LOCUS       DAJMZY010000001        98829 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.001, whole genome shotgun sequence.
ACCESSION   DAJMZY010000001 DAJMZY010000000
VERSION     DAJMZY010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 98829)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 98829)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..98829
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.001"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            37..153
                     /gene="rrf"
                     /locus_tag="OE968_000001"
     rRNA            37..153
                     /gene="rrf"
                     /locus_tag="OE968_000001"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            273..464
                     /locus_tag="OE968_000002"
     CDS             273..464
                     /locus_tag="OE968_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HCP7217319.1"
                     /translation="MKKVALILAIIGALNWGAIGILGTDLIGSIFGGTYEMVSRIIYF
                     IVGLAGLYLIPSLMSDDRE"
     gene            619..2028
                     /locus_tag="OE968_000003"
     CDS             619..2028
                     /locus_tag="OE968_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HCP7217320.1"
                     /translation="MFIINELNKIVNEEVISFHMPGHKKGQVYKKLGYKDILKNLYKM
                     DTTEILGTDNLHFPEGIIKNSQKKASRVFKSDYTCYLVNGSSCGIQSAIMSVCSPKSK
                     IITNRDCHQSVINGCILGDIDIEYVPCEISEETNILKGISISNVIDIIDKNLDAKAVL
                     LTYPTYYGMTYDLEYICNYAHSKKMVVIVDEAHGAHLGLSERLPKTALEQGADIVVQS
                     THKTLPAFTQSSMIHIQGDRVDIDKILNMLRITESSSPSYLLLSSLELAVDIYENKGK
                     ELMEELLNNIITFKNKVDSNINIYDTNDKTKIFISSKNMGLTGYELENILRNKYNIQV
                     ELSNYYGVLLICTIGNTAEDFSSLETALNNVVKEDFKFEKLENKKYPVVIPKKILTPR
                     EAFYKTKKSVKIYDSIGKVCGECIVPYPPGISVISPGEVISKEIIDYLMFCHSKGMIV
                     SGLKDVDLNFIQVIDLEDI"
     gene            2159..2848
                     /locus_tag="OE968_000004"
     CDS             2159..2848
                     /locus_tag="OE968_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate kinase"
                     /protein_id="HCP7217321.1"
                     /translation="MKGKLIIIESGSDASGKATQTEILYERLKKEGYMIKKVEYPNYE
                     SPSSALVKMYLKGDFGKNASDVDPYIASTFFTADRYASFKTDWEEFYNEGGIIIADRY
                     TTSNMVHQASKMDICDREEYLNWLADYEFNLFKIPQPDCVIFLDVPIEFSKKLMENRK
                     NKITGEEKKDIHESDIEYLEKSYNNALYIADKYDWKKINCVLDNKLRSIESIHNEIYK
                     IVLDSIKPMER"
     gene            2851..3786
                     /locus_tag="OE968_000005"
     CDS             2851..3786
                     /locus_tag="OE968_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HCP7217322.1"
                     /translation="MYFENIIGQDFAKKYLTNSIKKNKLNNAYMFEGMDGIGKKKFAD
                     ELSKLLLDYENLENSPDYVLIKPDGNSIKIAQIRNLQSDIVIRPHKDYKIYIINNAEK
                     MTVEAQNALLKTLEEPPNYAIIILVTNNKESLLETIKSRCDIIKFSPIPIEDLKRYLI
                     NTGIEEERAQLLAIFSRGSIENALNLSQSSEFSMMREDIQQYIQIMLDKNIVEILNIP
                     NNMEKYRGKIIALLDMMINYFRDIILLKENVNKNMLINVDKLVFIQNMNGKISYSQLS
                     KIIDIIEDAKSKIKSNCNFNISIQVMSLNIYEVIK"
     gene            3783..4676
                     /locus_tag="OE968_000006"
     CDS             3783..4676
                     /locus_tag="OE968_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HCP7217323.1"
                     /translation="MIKIVGIRFKSAGKIYYFDPVDFNIEQDMDVVVETARGLEYGKV
                     VVGPKDMDESELVSPLKPIIRIATEEDKKVYLENKEKAKETFELCQQKIKEHELTMFL
                     IDCEYTFDRNKLIFYFTAEGRIDFRELVKDLAAIFKTRIELRQIGVRDEAKSIGGLGP
                     CGRKLCCSSWLGDFQPVSIKMAKDQSLSLNPTKISGICGRLFCCLKYEHDVYSEAIEK
                     MPVVGALVQSDDGKGKVVEVNPLLEQIKVEFQDKTVKIYTREDIKILREPKKCDGCGG
                     KCKDNDGLDEATLRELKKLED"
     gene            4754..5500
                     /locus_tag="OE968_000007"
     CDS             4754..5500
                     /locus_tag="OE968_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HCP7217324.1"
                     /translation="MQLKDSERIDDLQLKGLKIIQDTNGFCFGIDAVLLANFTKIKKD
                     AKVVDLGTGTGIIPILIAGKSEAKKIIGVEIQEDVYEMATRSIKLNGLEERVEIINED
                     IKYIDKVLDINGYHVVTSNPPYMHIDGIKNPNDKKAISRHEVRCNLEDVIRAASRLVM
                     PRGKFFMIHRPTRLVDIITLGRKYKLEPKVIQFVHPRPQKAPNLVLVQFVKDGRPELK
                     ILDPLYVYGEDGNYTKELKAIYNNKDIGEL"
     gene            5501..6334
                     /gene="rsmI"
                     /locus_tag="OE968_000008"
     CDS             5501..6334
                     /gene="rsmI"
                     /locus_tag="OE968_000008"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HCP7217325.1"
                     /translation="MSGKLYICPTPIGNLEDITYRTLRILKEVDLIAAEDTRHSIKLL
                     NHFEISKPLTSYHEHNKDSKGDYLINKLIDGENIALISDAGMPGISDPGEEIIKQAIQ
                     NNIEIEVLPGATAFVTALVGSGMDTHRFIFEGFLDRDKKVRKAQLEELKEESRTIIFY
                     ESPHRLKDTLKDMLKILGNRNISINRELTKKYQEIIRENIETTIKIFEEKEVRGEFVL
                     IVEGFHGEKSKKENYDGLTDREYVLKLIESGMNKKDAIKIVCKDRKLKKDVVYKQVLD
                     L"
     gene            6357..7061
                     /locus_tag="OE968_000009"
     CDS             6357..7061
                     /locus_tag="OE968_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing protein"
                     /protein_id="HCP7217326.1"
                     /translation="MEIGKIIIESLKREDTHKIFIELDNKHELEKIIPKISCMKSVGE
                     CKYHVVNCFEHSINALKELEIVLNDKDFFPIHLRKHVSNYLKTYIEEGINKLHVLKLG
                     TFLHDIGKPDSMTLDETGRVHFTNHEKIGAQIIDNMGIKLELSTETYRLISKYVRYHM
                     ILLSLYKKNDLSRKELINVFNLVDEDTIGVIMLGYADIVSTVKLLGKSGEVSVLKTYM
                     EYILTNYLYKSNYTHV"
     gene            complement(7249..7677)
                     /locus_tag="OE968_000010"
     CDS             complement(7249..7677)
                     /locus_tag="OE968_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007287587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HCP7217327.1"
                     /translation="MDVTDYRIIEILQDDGRISMKDLGKIVGLTSPAVSERVKRLEES
                     GVIEGYKAIVNPDSLGRVIKAFIHISLPSNGYTEFIESAAKDPRIVECHHITGDDCLL
                     LKVIVKDMYELENVIDTIKKIGSTKTSVILSTPIQAKSIL"
     gene            complement(7714..9144)
                     /locus_tag="OE968_000011"
     CDS             complement(7714..9144)
                     /locus_tag="OE968_000011"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HCP7217328.1"
                     /translation="MRNLTLLTDLYQLTMLNGYFEKNIHEDIVVFDMFFRKNACDGGY
                     TIVCGIDQVVEYIDNLHFSDEDLEYLKNLNLFSDKFLKFLKEFKFTGDIYAVEEGTIM
                     FPNEPLITVKAPLYQAQLIETALLTIVNFQSLIATKASRVCFAAQGDPVFEFGLRRAQ
                     GPDAGIYGARAAVVGGCAGTANVLAGKMFDIPIIGTQAHSWVQKFDNELEAFQAYADV
                     YPDKCLLLVDTYDVLNSGVPNAIKVFKNISEKGYKPMGIRLDSGDLAYLSKEAKKQLD
                     NAGFSDISITASNDLDEYTITSLKAEGATINSWGVGTKLITSFDSPSLGGVYKLAASC
                     EKGVLEPKIKISENPEKINNPGYKKVIRIYNEDNKAEADLIMLHDEVIDESKPLEIFH
                     PTYTWKTKVFTNYKVKELLKPLYIKGRCKYNKKAVLEIKNHVQYELSTIWEQYKRLSK
                     PHIYKVDLSRNLWYLKTQMIDSKKVL"
     gene            9276..9860
                     /locus_tag="OE968_000012"
     CDS             9276..9860
                     /locus_tag="OE968_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore maturation protein A"
                     /protein_id="HCP7217329.1"
                     /translation="MIIIGKIWFYMVSIGIIGSLISKNMGELNKVILSETSKGIEFAI
                     SLAGIMALWMGIMNIAKESGLIEKIGQKLNPIMRRLFPSIPKGHKAMSYIVMNIALNM
                     LGAGNGATAFGLKAMSELQTLNNKKDTATNDMIMFMVINISSIQIIPFTIIKLRMDMG
                     AQNPSEIIFTTLFATIISTAVAIITCKFFQRRYR"
     gene            9876..10397
                     /locus_tag="OE968_000013"
     CDS             9876..10397
                     /locus_tag="OE968_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore maturation protein"
                     /protein_id="HCP7217330.1"
                     /translation="MEIFSNLLIPIIILYIVVYGKYKKIDVYDSFVKGAIDGLKAAWD
                     ILPYIIGIFLAIGIFKTGKGLDMLEWLFTPIANMMSIPKELIGLISVKPLSGSGALGM
                     YSELANRVGIGSLVEKMGATIVGSSETIFYTMAIYYGSLKIKNTRHTLSCAMISHVAG
                     VIAAVFICYVIFV"
     misc_binding    10463..10709
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            10793..12730
                     /gene="metG"
                     /locus_tag="OE968_000014"
     CDS             10793..12730
                     /gene="metG"
                     /locus_tag="OE968_000014"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HCP7217331.1"
                     /translation="MSKPSFYVTTPIYYPSGGLHIGHTYSTVAADTIARFKRFCGYDV
                     KFLTGTDEHGEKIQKKAIEQGMSEIEYLDGMIKDIKALWNTMDISYDDFIRTTEKRHT
                     DIIQKIFTKLYEQGDIYKGEYEGRYCTPCESFWTESQLLEGNKCPDCGRETYLVKEES
                     YFFRLSKYEDRLKELFKDDSFCFPAARKNEMVANFLDKGLEDLSVTRTTFDWGIKVPF
                     DEKHVIYVWVDALCNYITALGYMTDNDEEFKKYWPANVQIVGKEIVRFHTIIWPALLM
                     ALGLEVPKQVFGHGWILFADDKMSKSKGNVVYPEPIIERYGIDTLKYFLLREFAFGQD
                     GSYTHRNFVTRINYDLANDLGNLISRTVAMVEKYNNGIIPTAKVSTNFDADLKEQAVS
                     TRENFEAEMDKMQFHEALESVWKLVRRTNKYIDETMPWALAKDETKKDELDTVLYNLC
                     ESIRIIATLINPIMNETANKIYEHIGIKGQDDITTWESTKTFGLIGENVKVFKGEPLF
                     PRLDVEKEIEELTKMFSGKPPVEEKPLEHKEEITIDDLDKIELRVGKIISCEKHPKAN
                     KLLVSQVKIGPETRQIVSGIAEYYKPEDLVGKEVTVVCNLKPVKLRGVESQGMILAAG
                     DDGDPYVLPFTQGAKDGCEVR"
     gene            12760..13530
                     /locus_tag="OE968_000015"
     CDS             12760..13530
                     /locus_tag="OE968_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HCP7217332.1"
                     /translation="MLFDSHAHLNDESFDEDRDELIGSLKDKGVDLVVNPGADIETSI
                     TAIELAKKYDFIYSAVGVHPHDVSKLDDTAIETLRKLATENEKVVAIGEIGLDYYYDY
                     SPREEQKEWFKKQIELANELKLPIIIHDRDAHGDTFEIIKNTKNPEIGCVLHCYSGNV
                     ELAREYVKMGCYISIPGTVTFKNNKKTREVVREIPLERLFIETDSPYMSPEPHRGKRN
                     NPSQVSFVADKIAQEKGISYEEVCRVTKENAKKFFNIK"
     gene            13867..14298
                     /gene="phnG"
                     /locus_tag="OE968_000016"
     CDS             13867..14298
                     /gene="phnG"
                     /locus_tag="OE968_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate C-P lyase system protein PhnG"
                     /protein_id="HCP7217333.1"
                     /translation="MYTVDSTKILINMNLEKLEKIYSMIKDTSSISIIKEPNLATVMV
                     RANESVKNTTFNLGEILVTECSVKVDESLGYGIVSENNNKKAIYLAVIDAVLHSNNSK
                     FDELKNYINKSVYEENLRYEQEIIDEFSLINKTKVQFNAMD"
     gene            14313..14888
                     /gene="phnH"
                     /locus_tag="OE968_000017"
     CDS             14313..14888
                     /gene="phnH"
                     /locus_tag="OE968_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate C-P lyase system protein PhnH"
                     /protein_id="HCP7217334.1"
                     /translation="MVNYTQEIYRKMLDSASFPGKLNNIDNINIENNTKLLNGAIGIA
                     ITLLDQEVTFYIENYTQKDIKNIRALTMSNQIDYRKSDYIFLDINSEVDILQIKIGSF
                     EYPDESATIVHQVNDLSTYSQTKYIKLDLSGPGIKSKNSIYINGIREEFIERLSSINK
                     DYPIGIDLILVDKKGEIAFIPRSSKLSWEVL"
     gene            14891..15976
                     /locus_tag="OE968_000018"
     CDS             14891..15976
                     /locus_tag="OE968_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-phosphorus lyase complex subunit PhnI"
                     /protein_id="HCP7217335.1"
                     /translation="MAYVAVKGGEEAILQAKNILEFYRVKGDSLPIDVKQIEEQMSYA
                     VDKVMSEGSLYNKELSALAIKQAQGDILEASFYVRALRSTMPRITYSEPINTEEMRIK
                     RRISATFKDIPGGQYLGATRDYENRILNVELLEEDEKKNRHFRDSFINELETVDEIPE
                     FTKISNIFRKENLLQEEVCENKLEEVIDDITRNSLRFPVSRSAKLQALTRGESGVVSG
                     FAYAIVRGFGDEHPYISELRTGNVFIKVKHPIYEDEEIIIGDMLVTECEIVSKASQNK
                     TENSKTNSEDKNKMSLGYGLCMGNNENKAISMAILDKSLEPNSEKLAQDEEFVLLHID
                     GIDSLGFISHFKLPHYVDFKADVERIK"
     gene            15996..16865
                     /locus_tag="OE968_000019"
     CDS             15996..16865
                     /locus_tag="OE968_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-D-ribose 1-methylphosphonate 5-phosphate
                     C-P-lyase PhnJ"
                     /protein_id="HCP7217336.1"
                     /translation="MIYNYGFLDENTKKEIRRKILKAISIPGYQVPFGSRELPIAKGW
                     GTGGLQLTLSLIGKNDVVKVIDQGSDDSTNACNIRSFIASVSNVETTKDTLEATLIQT
                     RHRIPEEKLKSNQILIFQVPIPETLRIVEPSEVETRRMHSEEDYSRMWVYLYEDIVRF
                     NDISIAVEYPCKVNDRYLMNPSPIPRFDIKKLNMSDNLFLFGAGREKRIYAIPPYTKV
                     EPLEFEDYKFEEEKFEGKYCSLCNSTNTFLDEVYDSDTNEKYYSCSDTSYCEKVRLKN
                     NSIDVTIGGTWNE"
     gene            16858..17724
                     /locus_tag="OE968_000020"
     CDS             16858..17724
                     /locus_tag="OE968_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCP7217337.1"
                     /translation="MSKINDSKRLENIDKQVLIGRNINLIYGDGCEKCFESTGYESNN
                     ICKYCGSIVACNNVNLELYEGEVLGIVGESGSGKSTLLKILFFQEHANSGEVYISHYN
                     KDTNILELSDQKKRYIKNHFMGIVYQNPHLGLNLDFSSGGNIAEKLLMANLYNVEKIR
                     DRGKELLIKTNIPVERIDHKPKYFSGGMQQRVQIAKALSNNPPILLLDEVTTGLDVSV
                     QAEVLDLIREIQRELKISMIVVSHDFDVIKMLADRTIVMKNGSVIESGLTDQIMEDPQ
                     HPYTQQLINSLL"
     gene            17765..18478
                     /locus_tag="OE968_000021"
     CDS             17765..18478
                     /locus_tag="OE968_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCP7217338.1"
                     /translation="MKETILEVNNFSKDFELHALNKTITACSNISFEVSKGEFLGIIG
                     KSGAGKSTILKSIYKTYIPTTGEIIFNSEIYGNVDLAKIGDREMINLRKKEIGYVSQF
                     LKTLPRITAIELVVHSLIESGFEKDCSYDMAKDILNQFEIKENLWDAYPNNFSGGEKL
                     RLNLAQAMVKKPRLLLLDEPTASLDNQSKIYVKEKMLELKSQGTTMIGIFHDIEFMET
                     VIDKTFTMTKGTISESGVA"
     gene            18479..19648
                     /locus_tag="OE968_000022"
     CDS             18479..19648
                     /locus_tag="OE968_000022"
                     /EC_number="3.6.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-D-ribose 1-methylphosphonate
                     5-triphosphate diphosphatase"
                     /protein_id="HCP7217339.1"
                     /translation="MIKLIHNANIVLEDMILENGHLIIEGDTIKKVSNDKIDYAFDFN
                     EIDEIIDAKNLYVIPGIIDIHSDAIEKEIEPRPSTLLPFNMAFYELDKKLPANGITTV
                     YHSISLGDGVGVRSIDNSLKMIKNIDSYKNIDSKSINHKVHLRYEVLYYEGLEKVLEL
                     LDENKIDYLSIMDHSPGQGQYTNPTFYKEYATKVWGVTENYVDTWLDDLVNLHDNLDW
                     NKIANIIGIAKTKNINVASHDDDTLEKMDFIKNIGINVSEFPITLEVAKHSKKLGVLT
                     CLGAPNIVRGKSHNNNLKAMDAILEDCCDIVCSDYLPSAMIKSMCIVAERINNLNKAV
                     SLFTSNPAKAVGIYDERGSIKENKKADLVLVDIDSEYPKVVNTIVNGKTVYKREV"
     gene            19652..20488
                     /locus_tag="OE968_000023"
     CDS             19652..20488
                     /locus_tag="OE968_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HCP7217340.1"
                     /translation="MLTELHCHTSISDNNFTTEEIIKKAAEKNINILAITNHDTLSGL
                     DEALVLGEHYGITIIPGIEISAYDYKNRKRVHILGYNIDLNSQEIKNLCNPMVCDRHK
                     ASVKMVNKIIDLGYKISLEDVKKYSSKTGIFKQHIMKALIDKGYTDNIYSNLYKELFH
                     RGNGKVYVSLKYVDYRDAIKAIKNSGGICVLAHPGQMDNFSAIEEMVKVGLDGIEVYH
                     PSHNKELEKESLSYAKKYNLVVTGGSDYHGFYSQHNYELGSKSLNKEDLFKFRLALGG
                     VL"
     gene            20489..21484
                     /locus_tag="OE968_000024"
     CDS             20489..21484
                     /locus_tag="OE968_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCP7217341.1"
                     /translation="MSFLQVKNVGKSYGQVKVLKDISIDIEKGEFICLLGPSGCGKST
                     LLRIIAGLEDKHGGKIIINDKDMTNSPPESRNFGIVFQSYALFPNMNVYKNIAFGLEN
                     KNISKSNIDKKVKEVLEVVELSGYEKKYPSQLSGGQQQRVALARAIALEPDFLLLDEP
                     LSALDAKVRLKLREQIRSLHRKLGITTIMVTHDQEEALCLADKMVVMNRGEIIQVGTP
                     KEVYKNPETPFVADFIGTINFIDDGINKIAIRPEDIKVESNRDSKDKDIKVGEILDIE
                     FRGFNYRITVEYRSKQMKLDVVSKVAEQMKLCIGSKINFKIPKEGIVQYKSEGCA"
     gene            21502..23190
                     /locus_tag="OE968_000025"
     CDS             21502..23190
                     /locus_tag="OE968_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     permease subunit"
                     /protein_id="HCP7217342.1"
                     /translation="MITSKNKRRISDSTIQKYFLIFSVIVLIVFILFPLVSLLKNAFM
                     DTSGNFIGISNFSKYVENPSLIASFKNSIFVSTVSSLISLCLAFIYSYAITRTNIKFK
                     DFFKTMGMFPLFAPTMLYGISLIYLFGNKGIFTTMGLEVPLYGPLGIIISQILFTFPQ
                     AFLILSVALSMADYRLYEAADSLGASEFKKFCKITIPGIKYSLLSSFFVSFILAFTDF
                     GAAKVVGGNYNVLATDIYKQVVGQFNIPMGATVSMVMLIPVLIAFTLDKMASKKQGMT
                     ITAKSMPYKIKENKFRDRVFLIVCSFITLLIFILIFVSVIGSVIKLWPYNLSFTMEHY
                     TFKGILGSGIKTYLSSLKISTLTAIFGTIFVFFSAYMIEKVDKFPKLRQTAYLLSMIP
                     MALPGLVLGISYITFFNSASNPLNFLYGSTAILVIVNVVHFYSVCFITSNSSLKMLDK
                     EYELVAKSINIPFYKVFFNITVPMSITSILEIVVYYFVNSMVTVSALIFLYTPQTQTA
                     SISILKLDEIGYIGTSAAMAVLVLLTNIIVRLLYEFVTKKLKNNTQKWQQKDVA"
     gene            23202..24269
                     /locus_tag="OE968_000026"
     CDS             23202..24269
                     /locus_tag="OE968_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="HCP7217343.1"
                     /translation="MKFKKLVSLGVLSTLLLSVITGCSTDSSGSDSKSDSKTKGDLTV
                     YTAIEEDSIEPYLATFKEKYPDIKLNIVRASTGDITARLLAEKDNPQADVVWGVAATS
                     LLVADDQGMLEPYAPKGSEEIESAFKDDKEVPSWVGIDAWMTGITVNTKELSDKNIPV
                     PSSYEDLIKPEYKGLISMPNPSSSGTGYLTVSALIQIMGEEKAWQYMDKLHENIGVYT
                     QSGSAPATSAASGEYPIGISFGYRGIKLKEEGYPVEVVFPKEGSGWDIEANALVKKDN
                     IKEASKVFLDWAISKDVMNEYSKNYAVTTISTGNPIPEGFPKKPLEQMIDNDLKSAAK
                     NREDILNKWISKYDGKTEKES"
     gene            24706..25701
                     /locus_tag="OE968_000027"
     CDS             24706..25701
                     /locus_tag="OE968_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCP7217344.1"
                     /translation="MSFLQVKNVGKSYGQVKVLKDISIDIEKGEFICLLGPSGCGKST
                     LLRIIAGLEDKHDGKIIINDKDMTNSPPESRNFGIVFQSYALFPNMNVYKNIAFGLEN
                     KNISKSDIDKKVRDILEVVELSGYDKKYPSQLSGGQQQRVALARAIALEPDFLLLDEP
                     LSALDAKVRLKLREQIKSLHRKLGITTIMVTHDQEEALCLADKMVVMNNGEVIQIGTP
                     KEVYKSPKTPFVADFIGTINFIDDDVNMIAIRPEDIKVEFNRDFKEIDVKVGEILDIE
                     FRGFNYRITVEYCSKQIKLDVVSKVVEQMKLCVGSKINFKIPKERTIQYKSEGCA"
     gene            25719..27407
                     /locus_tag="OE968_000028"
     CDS             25719..27407
                     /locus_tag="OE968_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     permease subunit"
                     /protein_id="HCP7217345.1"
                     /translation="MITIKNKRRISDSKIQKCFLVFLVIALVVFILFPLISLLKNAFM
                     DTSGSFVGISNFSKYIENPTLIASFKNSIFVSTISSLISLCLAFIYSYAITRTNIRFK
                     NFFKTMGIFPLFAPAMLYGISLIYLFGNKGIFTIIGIEVPLYGPLGIIICQILFTFPQ
                     AFLILSVALSMADYRLYEAADSLGASEFKKFFKITIPGIKYSLVSSFFVSFILAFTDF
                     GAAKIVGGNYNVLATDIYKQVVGQFNIPMGATVSMVMLIPVLIAFTVDKIASKKQGMT
                     ITAKSMPYKIKENKFRDRVFLIACSFITLLIFILIFVSVIGSVIKLWPYDLSFTMEHY
                     TFKGISGNGIKTYLSSLKISILTAIFGTIFVFFSAYMIEKVDKFPRLRQISYFLSMIP
                     MALPGLALGISYITFFNSASNPLNFLYGSTTIMVIANIVHFYSVCFITSNSSLKMLDR
                     EYELVAKSINIPFYKVFFYVTLPMSITSILEVAVYYFVNSMVTVSALIFLYIPQTQTA
                     SISILKLEEIGYIGPSAAMAVLVFLTNIIVKLLYELTTKKLKTKTQKWQQKEVA"
     gene            27419..28486
                     /locus_tag="OE968_000029"
     CDS             27419..28486
                     /locus_tag="OE968_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="HCP7217346.1"
                     /translation="MKFRKLVSLGILSTLLLSVITGCNNASSGSNLKSNNKIKGELTV
                     YTAIEEDSIDTYLTTFKEKYPDIKLNVLRLSVGDITARLLAEKDNPKADVLWGVAATS
                     LIILDDKEMLEPYAPKGFDKVNPVFKDDKKVPSWVGIDAWMTGITVNTKELSDKNIPV
                     PSSYEDLIKPEYKGLISMPNPASSGTGYLTVSELIQIMGEEKAWQYMDKLHKNIGVYT
                     QSGSAPAILAASGEYPIGISFGNRGIKLKGEGYPVEVVFPKEGSGWEIESNALVKKDN
                     IKEASKVFLDWAISKDAMNEYSKNFAVTTIDTGNPVPEGFPKNPLEQMIDNDLKSAAR
                     NREAILNKWIEKYDGKTEKES"
     gene            28678..29208
                     /gene="rnmV"
                     /locus_tag="OE968_000030"
     CDS             28678..29208
                     /gene="rnmV"
                     /locus_tag="OE968_000030"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HCP7217347.1"
                     /translation="MIKEIIVVEGRDDVTAVKRAIDAELITTGGFGFPKGVMERIKAA
                     NERRGVIIFTDPDFAGEKIRKKIASEVPGCKHAFLPREEAKKDGDIGIENATPQSIIA
                     ALNKVRTENTEKRDEFKQVDLIRNGLIGNEEASLRRDALGKILGIGYGNAKQFLNRLN
                     NYGVEREEFIDALKQI"
     gene            29379..30248
                     /gene="rsmA"
                     /locus_tag="OE968_000031"
     CDS             29379..30248
                     /gene="rsmA"
                     /locus_tag="OE968_000031"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HCP7217348.1"
                     /translation="MDRLSSHNATKEVVQKYNFKFSKSLGQNFLIDSNIIDKILSGAR
                     ITRGDNIIEVGPGIGTLTREMGKIAEKVVAIEIDRNLIPILKDTLSDLDNTEVVNQDI
                     LKVDIQELVKDKLNGGPVKLVANLPYYITTPIVMKFLEEDIPVTDIVVMVQKEVADRM
                     NAIPGTKDYGALSIAVQYYCDTEIVAKAPRHMFIPQPNVDSTVIGLHVRDKRKYDVHN
                     EDIFFKTVKASFGQRRKTLLNSLGGLGFLNKDEIREVLKEANIDEKRRGETLSIEEFS
                     VLSNIINTKVSSK"
     gene            30314..31579
                     /locus_tag="OE968_000032"
     CDS             30314..31579
                     /locus_tag="OE968_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7217349.1"
                     /translation="MGSKRKFKRDYIILEAKDINFRYKERVLPKAFAKVEVNDEKAII
                     ALYVENLKYVKDGYKAVAIKDDHGLIDLGNIILNEQGRGEFVLDLEDYDDEIKGIALL
                     YERNIPLIGFKGNKLENYEDILFQEVEEEEYEEYEELEEEDEEIEDNEESDRDEGSEE
                     EYIIEEYDEDEYEDYWEDDEDIDEGELKARTEVEDSGDEEIEEFNNYKEIENYNRVKV
                     QEEYIDIEYDEEEEEEEEVFEVNREEDRFVSSKPTKSKKVQKDQNNIEKIKRANGVSQ
                     GESGNKQTSTLLMPRQIKKGLKLFKEVKPFVTDYIDKTRWWKIEINPTTLCGYTMPYL
                     GYLNVLNYTMYSDAVLHSYKYRHYLFGVQYDEYNKRKHYIYAIPGNRNEQPDNGSTGF
                     LRYQACDNRTNSLGYWLCFIDSRQRNIVR"
     gene            31730..32845
                     /locus_tag="OE968_000033"
     CDS             31730..32845
                     /locus_tag="OE968_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HCP7217350.1"
                     /translation="MINEQRILNEFLELVQIDSLSLKEGNVAKVLVKKLEEIGCSVVI
                     DNAGEKANGETGNIIATLKGNKEGKKILFSSHMDTVTPGIGVKPIVDEANGIIKSDGT
                     TILGSDDKAGIAAILEGLRYINENNIEHTDIQVVFSICEECGLVGAKNLDYGKIDSEY
                     AFILDSGGSPGEIIVKAPAQDVINVKILGKTAHAGLEPEAGISAIMVAARAIENMNLL
                     RIDEETTANIGIINGGTATNIVTGEVNIIAEARSLKENKLDVQTKHMVETFEKAAKDF
                     GAQIEIDVNRAYTPIDVSEDSEIIKLAKKAFSNLGIEGHTESTGGGSDTNILSKNGIE
                     AITLGIGMKNAHTLSEHIAIKDLYDSAKMVVEIIKEA"
     gene            33031..33927
                     /locus_tag="OE968_000034"
     CDS             33031..33927
                     /locus_tag="OE968_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HCP7217351.1"
                     /translation="METRYEEANKITIQSILWNVVLTIIKVIAGVIGNSSAMIADGLH
                     SASDIISSIGVLIGNYVSSRPGDREHNYGHEKAETLVSFVLSILLIFVSITIGIEAIK
                     SLFNLDALSVPSILPLVVSVISILIKEYQYRITIKVAKKINSPALKADAWHHRSDALS
                     SVAAFIGIGGSILGFKPLDPIASVVVAIFVAKVGISILISSVNELMDVSVDEEEIKEL
                     KFIVADTEGVKNLGDIKTRKHGAMAYVDLTICVDENLTVKQGHDIATKLEKHIIKHME
                     FVKGITVHVEPCTNCQGNKCNN"
     gene            33997..34794
                     /locus_tag="OE968_000035"
     CDS             33997..34794
                     /locus_tag="OE968_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7217352.1"
                     /translation="MSKKRKLKKKAAILIGVVVFFIIYFISFRIGINMEKDKSEVPKK
                     VEKEEEDNRSLRTQIKEKKKVYISDKNIENIKIEEDMWDEIKLFFSDFKKVRNTTSSY
                     EAVYEGYSDDGVKFSTDLNFFRVYTVNKEEYYKVPVSSKDAFKKLLDESIYTSFDLLS
                     HYKDWKEVTITHGKEIKKVHRWKFDDLAHKMISKRVVGKVQPEKSKERSDYNFTINIK
                     GDNFDVKVDTMGKDYVKVTSKKNVSYYEVHTSLFDYLKNEIFEIGKK"
     gene            complement(34849..36201)
                     /locus_tag="OE968_000036"
     CDS             complement(34849..36201)
                     /locus_tag="OE968_000036"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HCP7217353.1"
                     /translation="MNIHFIGIGGISMSALAEICINKGYQVSGSDSNESYLLDKLRDQ
                     GATIYIGQKKDNISDDVNMVVYTAAVHPDNEELVAAKEKNKLVMNRATFLGQIMREYK
                     NSIAVSGTHGKTSTTSMLSTIFEYADLDPTILVGGNLSMIGGNVKIGNSNHFITEACE
                     YVDSFLNFNPKISIVLNVEEDHLDYFSGIDEIKASFNKFGKLLPPEGYFIINGDDENI
                     DDILYDVKATIIKYGRDSDNDAVIKDIHFDNSGHGIFRIEYEGRDLGEFELSVYGLHN
                     IYNASSAIMAALVSGIDLETIRKNIKIYKGVGRRFETKGYYKNALVVDDYAHHPTELK
                     ATLAAAKKLKKSTLWCIFQPHTYTRTKSLLGEFSEAFYAADKVIITDIYAAREKDPGD
                     IHSKDLVEKLYQNNVDAIYIKEFEDIVKYLRENVKDNDLVITAGAGPIYKVADLLVEK
                     "
     gene            36420..37298
                     /gene="purR"
                     /locus_tag="OE968_000037"
     CDS             36420..37298
                     /gene="purR"
                     /locus_tag="OE968_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HCP7217354.1"
                     /translation="MKFKRTERIGAIVKILSDNPNKIYTLSYFTNQFNAAKSTISEDL
                     LVVKNVFEKLHLGKVITISGAAGGVKYIPKTSIAENAEFLMELCERICDKSRILSGGF
                     LYLIDLIYDPTIAAKIGKIFASNIEYVDADYVVTMETKGIPMALMTAKAMNLPLVIIR
                     KDIKVSEGPTLSMTYVSGNSSKVESMSLPRKALKPDSKVIIIDDFMRGGGTIKGMVDL
                     MNEFGAEVIGTGVFISTTNPSEKMVKDYISLIQLDVNGDKIVVEPNLKTFKDEYRNED
                     LDEEEDSEFEFEIDED"
     gene            37454..37732
                     /gene="spoVG"
                     /locus_tag="OE968_000038"
     CDS             37454..37732
                     /gene="spoVG"
                     /locus_tag="OE968_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation regulator SpoVG"
                     /protein_id="HCP7217355.1"
                     /translation="MKITDVRVRKLTEEGKMKCIVSITFDNLFVVHDIKVIEGHNGLF
                     IAMPSRKVGEGNFRDIAHPINAEMRQVLEDAVLQAYHEALVQWEVAAE"
     gene            37945..39324
                     /gene="glmU"
                     /locus_tag="OE968_000039"
     CDS             37945..39324
                     /gene="glmU"
                     /locus_tag="OE968_000039"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HCP7217356.1"
                     /translation="MNFKAIILAAGKGTRMKSKYPKVIHKVCGKEMVNHIIDVSKKSG
                     VKDTVVILGHEADVVKEKLAEEIIIAMQTEQLGTGHAVKMAKEYINDEDTIVVLCGDT
                     PLIKEETLKRLFEYHIENKYHATVLTTRVGNPTGYGRIIRDKKGDLLKIVEQKDANSE
                     EKMISEINSGIYCFNGKSLREALDLLNNNNSQGEYYLTDTAKIMRDKGLKVGAFAGST
                     IEELMGVNSRVELSKAEEIMRRRINESHMVNGVTIIDTNSTYIESDVMIGNDTIIYPG
                     VMLQGKTRIGSDCIIGMNSSITNSEIGDGTEIKNSTIIDSKVGENSTVGPYAYLRPKS
                     DLGNNVKIGDFVEVKNAIIEDGSKASHLSYIGDAHVGKNVNIGCGVVFVNYDGKNKFK
                     SIVKDNAFIGSNSNLVAPVVVEEKGYIATGSTITHDVPDGALAIARERQVIKEGWVEK
                     KNQKDDQSK"
     gene            39419..40369
                     /locus_tag="OE968_000040"
     CDS             39419..40369
                     /locus_tag="OE968_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003361732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate pyrophosphokinase"
                     /protein_id="HCP7217357.1"
                     /translation="MNTSGSEIKIIAGNSSKELAQKIADYIGVSVLDCEVGTFSDGEI
                     CVNMNETVRGCDVFVVQSTNSPVNDNLMELLILIDALKRASAGRITAVIPYYGYARQD
                     RKAKARDPITAKLVANLITAAGADRVLTMDLHAAQIQGYFDIPLDHLLGGTILANYFN
                     EKKIEDLVVVSPDLGSVTRSRKFANTLNGEVPIAIIDKRRPKANVCEVMNLIGDVKGK
                     NVILLDDMIDTAGTIVNAANALKEFGAKDVYACCTHGVLSGPAIERIANSEISELIVL
                     DTIQLPEEKRIDKIKIKTVAPLFGDAIRMIFSNESVSKLF"
     regulatory      41213..41298
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
     gene            41460..41981
                     /locus_tag="OE968_000041"
     CDS             41460..41981
                     /locus_tag="OE968_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HCP7217358.1"
                     /translation="MKLKKNKKGFTLVELLVVIAIIGILAVVAVPALFSNINKAKVAS
                     VESDYSSVKSAALSYYSDTNKIPVTTTDKAGLTILETYMESLPDKADIGGKYKLIKVG
                     NKLVLQIGTDTEGVTLTEAQSAKLLSDIGKDKIYTGVTGDNFGDELTDTTKIDNKALY
                     IVLIDNTVMDSTK"
     gene            42133..43809
                     /locus_tag="OE968_000042"
     CDS             42133..43809
                     /locus_tag="OE968_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HCP7217359.1"
                     /translation="MAKKVRIGDKLVEKGYITEEQLKWALSEQKNSGKRLGEFLVQEG
                     LIDSNLLISVLKELLDIESIFLEGTEIDTLATKMVPENICKRYTVFPFKIDGNKICLA
                     MSDPQDREAVQDVRRMSGKDVEIFISSTEDINKAIGHAYAHSEINKAMTEYNKNRTGG
                     VRETVILEEDVNAAPIVRLVNNILENAVRMEASDIHIEQSENYMRVRFRIDGMLREYM
                     RMNSAPYKAVISRIKIMSDINISEKRIPQDGRIYLKVDNKPIDFRVSTMPTNRDEKIA
                     MRVLDKSNFMVSKEVLGIDEHGSKIYDELINTPYGLILVVGPTGSGKTTTLYSMLNQL
                     NTENRNLLTIEDPIEYELPGVNQSQINEKAGLTFASGLRAFMRQDPDIIMVGEIRDTE
                     TAEIAIRASLTGHLVLSTLHANTAVGAISRLLDMDVESFLITSSVLGVISQRLTRKIC
                     EHCKVSYEADIGEKKALGIDVNESVTIYRGKGCERCNNTGYKGRLGIFEMLEITPEIK
                     ELIDSSANQREILKMARKQGMVSLKEDIVKKVLNGKTTVEEMIRIILMTD"
     gene            43821..45029
                     /locus_tag="OE968_000043"
     CDS             43821..45029
                     /locus_tag="OE968_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HCP7217360.1"
                     /translation="MKSFKYTVIKEDGKKQTDVIEANDFNEARNLLRKRNLRVIEIKE
                     SKNKNIRLSSRKRKKDLGADQISHFCRQFAIIVSSGINSISGLETLARRSTNITLREE
                     INRIVAEIKVGSTIADSMLSSKSKFPKLLGAMVATGEATGKLDEVLKSMASFYASEHR
                     VKQKLRNAATYPLIVLISSFIMIFIFTTFMVPKMINSITTVGATLPLITRIVMGFGMF
                     MKKFWIIVLLVIILFIYQFKKYLKTSVGRAHKDRVINKIPVLGKGINCMVATRFSRAL
                     YLFVSTGYPLVQGLDYIIDSVNNTMAEKILASAKDGITRGEGLAENLERYTYFDSVLV
                     QMIAIGEQTGELENISRQMAEFYEYESEIYLNRMASMIEPVLIIAVGIIVAILVVSIF
                     MPMLSIYDAM"
     gene            45044..46756
                     /locus_tag="OE968_000044"
     CDS             45044..46756
                     /locus_tag="OE968_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PilN domain-containing protein"
                     /protein_id="HCP7217361.1"
                     /translation="MNKVYVSYYGDSISIVEGRYKHDKDKFYVKNFNVFSIEDIAQDF
                     SKEKYALLRYALENVKLKSRHVVFCLNTRDVILKPQKLPNMDKKDLDGFMKLEMDEMM
                     ALESDEYVFSYEVSSETPDNSDGDESSLNLIIGAIQKEEVNAIVEIMHEFDLVLDRID
                     TLSTAYLRMLKNLDYNDIMVTNISDNSTIINIYKKDTLFISDNIPIKITAKDMDMQLL
                     NVVEESKGLMNYYSSRNFGKVTDTILILGKRYSNKLIYETFSSAFSSYVSQGLTEIMD
                     ISDMITGDIDEDDINSIVELLGSMIEPKGKRDFENINFLPMDILRKQIKAKQMKNILK
                     IAPIVILILAIPYLCLIFSNNLANKELENVNGEIRNIESAYYQIGNIEKMIQSKSEEI
                     KVYDMLIGKKVKWENLLDDIDKNTPSKVELTSLSTTYQNLGTNNKADNSKSNKTTTDK
                     SSNNETKSSTKSDSNGDKTDNDLNEDKTTNVSEALTGNSETNSNNTDKDDKTPLYDKI
                     PNVINIEGNAKDSSYVGQFLYKLKGLYYFKDVKLHSIKSNAEDSNYTFSMTLYLKEGV
                     LTNE"
     gene            46749..47657
                     /gene="pilO"
                     /locus_tag="OE968_000045"
     CDS             46749..47657
                     /gene="pilO"
                     /locus_tag="OE968_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 4a pilus biogenesis protein PilO"
                     /protein_id="HCP7217362.1"
                     /translation="MNKDIFKKDIKDIFKMEVSLKGILIKVIILLAILSYGYFGLYPQ
                     YQKYIATKNSVKQATEKLNIYKEKTALMPKYEKQLEEVESELKEKSKNLLYDMQDGLF
                     LIGLDKKMKAYNIDLTSYDVGNVKEYEHFYGISTTISVRGDYRNVKKLMAYLEEQKNV
                     TQILDYTMTSYIEPEKEEEETTNNKDLIKNVNINKDTKIYWVEGENKWHLYKDCPLIK
                     EGEIIKNDKLLDRSTNYLCNTCVLRAATEKEAKKEVVAPKAEGVVDATFKFIMYTKEN
                     TTMILDTDNPSSWRPGKYNPFKSSAK"
     gene            47684..48250
                     /locus_tag="OE968_000046"
     CDS             47684..48250
                     /locus_tag="OE968_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HCP7217363.1"
                     /translation="MSLYKNNEKGLTLLEVIIAVFILTIVLSISYKVFNGITSAVKKQ
                     QIITDAQVNINLINKYLNRDLENCKELTKTGSGNNYEYNIEMPDNVVKYEVSIETKKN
                     TEVYSVTRIQNNTIDTENEVREEIIYNQPLVQNNKEMKETPFKIEKQTGKSIYTVSIY
                     YNESVQESHKNSNLNNKTYTFDVMSRIG"
     gene            48287..48814
                     /locus_tag="OE968_000047"
     CDS             48287..48814
                     /locus_tag="OE968_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HCP7217364.1"
                     /translation="MSKKNSERGFSLIEVLVAMAIMGIVLFAFFNIINTNNKANTKND
                     TDITSLNYVQSEIENLREKIKSGEFDFDSLDKLEDGTVVYEKLIDKSKKVVYDKVLSE
                     GDVSLYDTPYEKITTIKDEDGNLIDKGNITNKIKTIVEDKSGQIYKIAVTGKSMNDYS
                     SKKEVKIVTEIFKDK"
     gene            48835..50373
                     /locus_tag="OE968_000048"
     CDS             48835..50373
                     /locus_tag="OE968_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7217365.1"
                     /translation="MRKWNKFKSERGAALVLVLVVVALLSIVGLIFSNQIANRIKSTK
                     TTNEGIQAKYLAETCVENSIDKAYEKLYDELEKMDNEFKSENQEKSISRSKLRNISDE
                     DFNNQDEENIEAERLGYMNNINFYLNKASSDLEKASMELKKLYDLDMLDYRDIEYVDA
                     NIISHRNSILEICKNYTSGDISKINEYILKEDIDSTTLIEAKLVNNDILLKKFLEENK
                     IENEHLNSAFSHTYKALDNISLAMQNMIEYRHTFHIDEPKVEVSNGIPDSQQYYELIQ
                     NPIINSMEYSWNSKWDTLENLLEILPNQTQGFNSLRVHLRNNVRKFEKLSDNISSGKK
                     NTAKNFLKYKELLYEISDQCNQLKSMSYEKIPVKYDNMALITTFDYIQNELLAEIKCR
                     LKELKPQEIDKTEGITIKIPFYKADYDMTKEGWPKLKENGSGAELSLMVTGDKNGIKE
                     VEVTDGKKNIIGLGVEENSNSKYKVDAIVNFNLNIDTNVVGNYDIKDKILINHDISSY
                     KKVN"
     gene            50473..51555
                     /locus_tag="OE968_000049"
     CDS             50473..51555
                     /locus_tag="OE968_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV pilus twitching motility protein PilT"
                     /protein_id="HCP7217366.1"
                     /translation="MYIYDLLEQGIRLNASDIHITVGTNPVARVKGGFVKLSEQILTS
                     EVTMQMAKDIAGESMFKVIEEHGEADFSASLKTGERFRVNAYRQKGNYAIAIRTITAE
                     IPTFEKLGLPESIKSFTEKHKGLVLVTGPTGSGKSTTLASMINIINEKQQKHIITLED
                     PIEYVHHHKQSLVNQREVGTDTESFHSALRAILRQDPDVILIGEMRDPETVSIALTAA
                     ETGHLVFSTLHTVGAAKTIDRIVDMFQPSQQQQIKTQLSTVCEGVVSQQLLPTADGKG
                     RIAAIELMFATPAIKNLIREGKTYQIPNMIQTGVKVGMKTMDQDLMELYKNGKITKDM
                     ALSRCTDQEFMTRMIGGVNYNGYYNR"
     gene            51536..52318
                     /locus_tag="OE968_000050"
     CDS             51536..52318
                     /locus_tag="OE968_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HCP7217367.1"
                     /translation="MDIIIVNLYVFIVGIVFGSFFNVCIFRIPEGISISRPPSHCMSC
                     NTRLKPIDLIPVLSYLMSGRKCRYCYEKISSRYAIVELITGLLFLTVFMLYGISTSTI
                     YYLVLVSLLIIITFIDIDHFIIPDKILVFGAIFSMIFNLLFKEIPVKDSILGVFICGG
                     SVWIIVLLIEFVIKKECMGGGDIKLFAMLGFYMGVKNGLLTALLSVYVGAVYGICVII
                     ISRIKGKEYNSVIPYGPFISIGALITILSGKQLLELYFSMVI"
     gene            52420..53070
                     /locus_tag="OE968_000051"
     CDS             52420..53070
                     /locus_tag="OE968_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HCP7217368.1"
                     /translation="MEYIIIISLFFAHLINKSLCVFCDREKKNLYNTFFIYIITVVLS
                     VLIYLKFGISVECVQYMVLIPFLIIISIVDYYTIYVYDITIVSGIIVQGIIFLAFFNI
                     VQFDYINHIFGLLIGFIIPYIIAKLTKGLGYGDVGLYSLCCFALGNNYGFYVIVLSFI
                     LAFLFFIILYITKIFKDVDIRKQIPFTPFISLSTILIIFTEYNIFNFYYNLLYKFI"
     gene            53084..53644
                     /locus_tag="OE968_000052"
     CDS             53084..53644
                     /locus_tag="OE968_000052"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HCP7217369.1"
                     /translation="MYVVVGLGNPGKKYEKTRHNVGFDVIDILAKEYNISVTKIKHKA
                     LIGEGRVGTEKVLLVKPQTYMNLSGETLIDIYKYYKVDLSNIVVVYDDIDLEVGKIRI
                     RKKGSGGTHNGMKSITKCLGSNDFPRVRVGVSKPEAGQDLADFVLSRFRKEESDNINE
                     ALEKAADAIDSIIRENIDMSMNKYNG"
     gene            53661..57047
                     /gene="mfd"
                     /locus_tag="OE968_000053"
     CDS             53661..57047
                     /gene="mfd"
                     /locus_tag="OE968_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HCP7217370.1"
                     /translation="MNDVFLYPLQNSKEYKDIINCIKNTKGSLLVNGLLPVQKPHISY
                     SIFNDLSRQMIFITSSDLEAKKVYEDLSFYMEDKVEYLGFQDIYFYHLDAKDRNEEAK
                     KLKVLLKLANKEKIILVTSIEAVLRKYIPKQVLLDSVSHYKVGDSLDLEKLTEKLVSL
                     GYERVSKIEGFGQFSIRGGIIDVFSLEYTNPIRMELFDDEIDSIRTFDVYSQKSIDKL
                     QQFSITPSREFIYPEKTTDALVKLKKETTKNTDEGTFQNIDYISSKTYFEGVENYIDY
                     IYPEENKSIFTYLADDAIVFINDITRLKERCENYINEFRENYKLNLERGLAIKNQGKL
                     LYHYTDLEYLVKDKSVVLNSLLPKSINNFSIKSIINFESREVPTFNGKVDLLVEELNR
                     LKYNGYKIILATNTLERANKLGKDLLDKGLETTISKDRDIEIKSSQVIIVPAHINSGF
                     QYKSIKFVVITDNEMIGVYKRASKTSNKKVKKGKKIESFLDLSVGDYVVHENSGVGRY
                     TGIEQITVNAIKKDYMKIVYQGGDNLYVPIDQMDKVQKYIGAEVEKVKLNKLGTNEWT
                     KAKAKVKKEIEDMTKDLIELYAKREKIQGYKFSKDTPWQAEFESLFPYQETEDQLKAI
                     EETKKDMESSKVMDRLVCGDVGYGKTEVAIRSIFKACMDQKQVAVLVPTTILAQQHYN
                     TFKERFENYPLRVEVLSRFKTPKQQKQIIEDAKKGLVDILIGTHRIISKDINLPNLGL
                     VVIDEEQRFGVKHKEALKKIKSTVDVLTLSATPIPRTLHMSLSGIRDMSVIEEPPQER
                     HPVITYVTESKESVIQDEIERELSRGGQVFFVYNRVEHIEEMASMIQKLVPDARVAVA
                     HGRMTSKSLENIILGFLNKDYDVLVCTTIIETGMDISNANTMIIYDADKMGLAQLYQL
                     RGRVGRSSRQGYAYLLYEKDKTLSEIAEKRLKAIREFTEFGSGFKIAMRDLEIRGAGN
                     ILGSQQHGHMAVIGYDLYVKMLNDAIKKVKGEPIVEEIDVEIDLSVNAYIPDNYIKDE
                     LIKIEMYKKIASIENKEDMLDIQEELEDRFSDIPKPVQTLLTIAYIKSLCKILKIEKI
                     RQLKDEILLVPITKYRTKQKIGYNIVTELEELLEKMCKVK"
     gene            57078..58073
                     /locus_tag="OE968_000054"
     CDS             57078..58073
                     /locus_tag="OE968_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HCP7217371.1"
                     /translation="MKKVITLVIAMILVVSVTACSSSKGETVATVEGTKISSDEFKKT
                     IALYKDSMEQTYGKDIWDKEVEKGVKYKDKFKDLILDQLITTEVIYSQAKKDNLLPKK
                     EDVEKSFKELKDAMGKDEKYKEQLKKLGIDDEFLRDQQEKDLAMQNYQSNFAKKTKIS
                     DEEMKKYYDTHKDEFKKDEVEASHILLKTVDDNNKPLSDKEKAEAKKKAEEALKEVKS
                     GEDFAKVAKKYSQDTSASDGGKLGFFSRGQMVAEFEDAAFSMKKGEVSDLVETQYGYH
                     IIKVTDRINEQTSFEDAKETIKDQLLKNKYQEQIEKLTKEAKVEKDEKVINKITI"
     gene            58197..58736
                     /gene="spoVT"
                     /locus_tag="OE968_000055"
     CDS             58197..58736
                     /gene="spoVT"
                     /locus_tag="OE968_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein T"
                     /protein_id="HCP7217372.1"
                     /translation="MKATGIVRRIDDLGRVVIPKEIRKTLRIREGDPLEIFTAKDGEV
                     ILKKYSPIGELNEFSQEYAETLAEVLGYGVLITDLDSIIAVSKLPKKDYKEKSISDEL
                     EAIISERTVKYSKDKNILPLFKEDQKEYTSQVIMPIISASGDCIGSIVVVSKDKDTIA
                     ESEEKSLKIAANFLGKQVQ"
     gene            58856..60469
                     /locus_tag="OE968_000056"
     CDS             58856..60469
                     /locus_tag="OE968_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HCP7217373.1"
                     /translation="MNNNKNKDSFLKGALILGLAGVIVKIMGGFFRIPLGNMIGSEGM
                     GYYQAAYPVYTLFLTLATAGFPTAVAKLVSEKVAIGNFKGANKIFKVSHTVLFITGII
                     SFCILFFGADYIVTNVMKNPGALYSMKAIAPALLFVPAMSAYRGYFQGRQDMTKIAVS
                     QVAEQFFRVVLGLTLAYLLMKSLGQTFGAAGAISGATIGSIASMLYLVFAYMLGRKER
                     RAEIDASQRFKDERVSYIFKKLLTVAIPITIGASVMPLVNMIDNVIVIRRLMEAGFTY
                     KVANSMFGQLTGMAMATINLPAVITTAMSMSLVPAISKAYALGNKSKARKDTKSAVKV
                     TLLIVLPCAFGMASLAIPIMGLLFPHEPSSVGTILFTLTPCVLFLGLIQTLTGIIQGM
                     GKPIVPVIALCVGMLCKIVISYTLTGIPDINVLGSAFGTVTAYFVAAMINLLYVKKHM
                     NVNFSKKEFIIKPFITVMTMFIMVKLSYGALVGFLGNSISTIIAICVGGIVYVVVILG
                     IGGIKKEEILTMPKGDKLYKLLKKVKLIR"
     gene            60576..62024
                     /gene="mazG"
                     /locus_tag="OE968_000057"
     CDS             60576..62024
                     /gene="mazG"
                     /locus_tag="OE968_000057"
                     /EC_number="3.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside triphosphate pyrophosphohydrolase"
                     /protein_id="HCP7217374.1"
                     /translation="MGKISIVGLGPGDYSLISQGVLESLINSPKVFFRTEKHPIIDKL
                     KETIQYTSLDYFYEKEENFDNVYLKISEFIIEESAKGDLVYAVPGHPRVAEKTVSIIE
                     RLANEKHIAVEILPSMSFVDAMFNYLAIDPSEGFKLVDAFEIENSYIDLDTSMIITQV
                     YDKFIASNVKLKLMEHYDYNQEVCIVNGAGVKDLESKKFIKLCELDRNENFFDYLTSL
                     YIPKSSKKMYNTVHDLEIIVNTLRSPSGCEWDKKQTHQSLKNSVIEEAYELCNAIDNN
                     DIDEMVEELGDVLLQVIFHCQIGNEEGYFDLKEVVNGICKKLIHRHPHIFSGAKLDMS
                     KFEKTWEELKKEEKGESTITDGLRRIPKHLPALMKASKVQHKAALVGFDWDNVEDVFK
                     KIEEEYQELLDEHRVGNIKYIKEELGDLLFSIVNLARFLDIDSGEALNCTTEKFINRF
                     DFIEKSAMNLNKKLEDMTLEEMDEFWNQAKKQ"
     gene            62113..62391
                     /locus_tag="OE968_000058"
     CDS             62113..62391
                     /locus_tag="OE968_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003153447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HCP7217375.1"
                     /translation="MNKAELVSKMAEKSGLTKKEAEAALNAFMSSVQDALVNNEKVQL
                     VGFGTFETRERAARQGRNPRDPEQVIDIPASKAPVFKAGKGLKDIING"
     gene            62463..62705
                     /locus_tag="OE968_000059"
     CDS             62463..62705
                     /locus_tag="OE968_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HCP7217376.1"
                     /translation="MRLDKFLKVSRIIKRRTVAKDACDKGIVTINGKVAKSSSEVNIG
                     DTLEIQFGEKKMKFKINEVKEHVLKNDAKEMYKILE"
     gene            62767..63021
                     /locus_tag="OE968_000060"
     CDS             62767..63021
                     /locus_tag="OE968_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein YabP"
                     /protein_id="HCP7217377.1"
                     /translation="MEQNITLKDRSKLVISGVEHIYSFNDKRVELKTSVGEMVIEGEN
                     LDMSKLSIDENIISIDGTINSMVYAKPKKPQESFLKKVFR"
     gene            63022..63555
                     /locus_tag="OE968_000061"
     CDS             63022..63555
                     /locus_tag="OE968_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7217378.1"
                     /translation="MIPFTQDVSIFYATIYGGILIGVLFDFYRGLRGNFKFINYFAII
                     FDVLFWFLATVIIFVTINLTEFFDLRYYHFVALFIGFILYYNTISKIVLSIINKIIRF
                     VRNSFKKVTHYIVSFLNNLYYVIIYSLHLLFDIIFYIPNIFIATRKSIKRKSNKKLKN
                     KKKSKPKKKKNKTKKRV"
     gene            63561..63845
                     /locus_tag="OE968_000062"
     CDS             63561..63845
                     /locus_tag="OE968_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HCP7217379.1"
                     /translation="MNLRKKFSGQIIVISLFLGISIFSMMTGFVFEYTKAKEYKKEIA
                     SLNKQLKKTEIQINSLKKDEKSYEGDLEDIARKRLNMVKPNETVYVDINR"
     gene            63958..64878
                     /locus_tag="OE968_000063"
     CDS             63958..64878
                     /locus_tag="OE968_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ppx/GppA family phosphatase"
                     /protein_id="HCP7217380.1"
                     /translation="MKVGAIDIGTNSMRLLIADYRDGNFINRKKFVNTTRIGYGVDSK
                     GYIKEDAIKRNIKALKEFSDKCNDEKCEKIYCMGTSALRDSKNGDYFVKLAKEETGID
                     VDIVTGIEESNLGFKGVLEGIQGDDTIIVIDIGGGSTEFIVGDSEGIKFNKSENVGAL
                     RMTERFLKHDIIEDEEFEAMSSFIYDEIDKTLNHIKDRGLKTLIGIGGTITSLSAMNQ
                     ELEIYSMEKIHNSKIHKKEIEEILQKLIKMTLSDKKNLKGLQEKRADIITAGVKILNI
                     IMEKLEIEEITVSEYDNLEGLICQKSKKMY"
     gene            64968..67340
                     /gene="spoIIE"
                     /locus_tag="OE968_000064"
     CDS             64968..67340
                     /gene="spoIIE"
                     /locus_tag="OE968_000064"
                     /EC_number="3.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein E"
                     /protein_id="HCP7217381.1"
                     /translation="MQRSVAVVKNKTVKPNVIKLISGYIDFTTAAFAVMGFLLSRSII
                     VDSVAPLGIAFFICASKIDKYKIPVFISTLLGILLSSNDFGNVAKYAVCLTIFMAMNK
                     KLKLSDSIAKVAFIGAIILLPISMGQAFFSNRYVYGLLIAGVEAIIMFISIYVFSYGI
                     GLMANVNNRMSVRTEEAISISLLLTFSIMGIGDISLFGISIRTILSTVLILLTSIVGG
                     ATMGASSGVIIGVASILNNMTSAVYMGIYSFSGLISGAFNKINKYFCILGYILSWTII
                     YLYTSGITSNMMQLRDILLGCLIVLVLPERLFNKIEKLIKSNVASNEIVYDYIMRSKN
                     LTNSRLNSIYKTYDDLADTFDKIREKDKVLDQRDIANVIDMIHNDECKSCSMRRMCWE
                     SRFNHTYTMIYNILEKIEEKGELSLNDIPKNFRKECMKPESIVKISNHYYKMFVLDYD
                     WSVKFSESRKLIANQIRSISKSIKSLSQDLEGDIMLDIEKEKNIYEQLERYDITVDKV
                     SYLTKSNSEFEISIEKKTCHDGCMCEDKIVNIISDLVGENMSVRKIGCHCLGGKCKAT
                     FVKSQKYKAVTEVSAMSRDGHILCGDNYTYMEINDGKYMMAISDGMGKGKKAYEESSA
                     TIDILEKMIDAKIKDEIVIDTINNMLLLKSSEEMFSTLDLGILDLKRGCLETIKMGAC
                     STYIKREDGEVDLISSSSLPVGILSDVKIDRKNVKVKEGDYVIMVSDGIVDAGRNNNL
                     GDNWLIYFLKNIETTNPKEISNLILDRALELQALQIEDDMTVLVTKICTK"
     gene            67691..69583
                     /gene="pepF"
                     /locus_tag="OE968_000065"
     CDS             67691..69583
                     /gene="pepF"
                     /locus_tag="OE968_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HCP7217382.1"
                     /translation="MNRKLCKAIIPLFISIFCMLIISIKADQGYQKNNDRAITVMNNN
                     DTEDDAEKKQEIDYEKTCWNLQSLFKSDDQWKKELKSFDKDTKELKNYIGKVTKSPTH
                     LSFALNIKEKLDIRLNKLSAYVKLKQDTNKNSYKYLDMNDSMSKSYGNYMGICSDLEL
                     EILKLSNKDYKKIISNKNINRKYGAYLRDIRRNKVHYLDDKSEDILSKVSSISSLPSQ
                     VYELFRNMDRKTNLTPAQYASELESSDRENRKKAYQDELITYNDNINTIAGLITGQVK
                     KNIFYSQERGYESSLEMYLEADNVDEKVYNNLIRTVNSNMDSLHKYIDLRKKVLKLDK
                     VHSYDMFVPMVKAVDNNINYEKAQSIVYSALSPLGKEYNDVVYKAFNEKWIDVYSHEN
                     KVSGGYCLSVYENHPYILLNYNNSLGSVSTLSHELGHAVYEYLSSKNQNYFNSNPSIF
                     THEVASTTNEALLYEMLIKEAKGNDEKAYYITQYLDLIKDTLYTQTMYAEFEKTIHEL
                     VEKGKSVNALVLNDVWGQLLKKYYGQSYELDQLSKVGWARIPHFYNSFYVYKYATGCS
                     AGVSFAQDILKNGSDNYMSFLKKGSSDYPINLLKSSGINLTNTKPIENTIKKFDSLVA
                     ELEKLL"
     gene            69697..70662
                     /gene="galU"
                     /locus_tag="OE968_000066"
     CDS             69697..70662
                     /gene="galU"
                     /locus_tag="OE968_000066"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HCP7217383.1"
                     /translation="MQVKVKKAVIPAAGLGTRFLPATKAQPKEMLPIVDKPTLQYIIE
                     EAVASGIEEILIITGRNKKSIEDHFDKSVELELDLEKKGKKELLEVVQNISNMINIHY
                     IRQKEPKGLGDAIYCARHFIGDEPFAVMLGDDIVDNDVPCLKQLTDAYEEYRTTILGV
                     QKVNQEDTNKYGIIEAKNIEGRVYKVKDMVEKPESGKAPSNIAILGRYIITPEIFDIL
                     KDLPPGKGGEVQLTDALKILSKKEAMYAYNFEGKRYDVGDKLGFLEATVDFALKKEDL
                     KEDFIKYLKHVCSEFDKNNNVLYNNTDEKIDLIEVNEARELEIQK"
     gene            71162..72766
                     /gene="rho"
                     /locus_tag="OE968_000067"
     CDS             71162..72766
                     /gene="rho"
                     /locus_tag="OE968_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HCP7217384.1"
                     /translation="MRRIFLILDDKVLEGLGSKTLVELREIAKELKIKSITTYKKNEL
                     IEIINSKSKNEEKVNEETKEKNEDIKEDIKNRKENIERESIEKEVEYKSPTKSYNKKE
                     IDTQNISQNQEHRNQRNDYNKTTSVNDSNKSSNISNRMVRNNNKNYYMPKQVDESKIV
                     DEFNTSKEDEVVGVLEILPDGFGFLRGSNYLSTEGDVYVSPSQIRRFNMKTGDKIKGI
                     TRHPKSGEKFRALLYVQKINDENPDTAIQRNAFETLTPIFPEERLTLETNRNEIATRI
                     IDLISPIGKGQRGLIVAPPKAGKTVLLKSVANSIAKNHPNVELIVLLIDERPEEVTDM
                     KESIEGDVIYSTFDQVSSHHVKVAEMVLNRAQRLVEHGKDVVILLDSITRLARAYNLT
                     ISPTGRTLSGGIDPGALHGPKKFFGAARNIRQGGSLTILGTALVETGSRMDDVIFEEF
                     KGTGNMELHLDRKLAEKRIFPAIDIYKSGTRRDDLLLDDEEKTALWRLRREMSNNSVM
                     EITDKVIELIKRTKDNKEFVKSIKNL"
     gene            72919..73119
                     /gene="rpmE"
                     /locus_tag="OE968_000068"
     CDS             72919..73119
                     /gene="rpmE"
                     /locus_tag="OE968_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018591942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L31"
                     /protein_id="HCP7217385.1"
                     /translation="MQKEIQPKYNPVEVRCACGNTFVAGSTKDEIKVEICSECHPFYT
                     GKQKNIEKGGRIDKFKKRFKMD"
     gene            73264..74157
                     /locus_tag="OE968_000069"
     CDS             73264..74157
                     /locus_tag="OE968_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1385 domain-containing protein"
                     /protein_id="HCP7217386.1"
                     /translation="MAKQAVGGQAVIEGVMMQSKDKRAVAVRKSDGEIALKEDRIKSW
                     VRDKNIDKIPFVRGSFVMIDTMIQGIKSLNFSSEFFMEEAEEDKFDLFIKKIFKDKAN
                     DIIIIFSLVIAMLLSAGLFIFIPTLVGGAFSKVMPNDFMLNLIEGIIRIAILFAYIVL
                     ISRSKDIERVFQYHGAEHKSIYCYENDLELTVENARKFKRLHPRCGTNFLFIVMAVSI
                     ILFAFFGWPNPILRIFMRIICVPIVAGLSYEVIRVLGKYDNGFTKIIAYPGMMLQYFT
                     TKEPDDEQLEVALEALKAVVD"
     gene            74175..75023
                     /gene="prmC"
                     /locus_tag="OE968_000070"
     CDS             74175..75023
                     /gene="prmC"
                     /locus_tag="OE968_000070"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HCP7217387.1"
                     /translation="MTIKDIIIKYSDKLKDISDTPRLDTELLLQKTLGVDRLYIHLNL
                     NKELTEEQKTKFMGFAEERLNGRPIAYIVENREFMGLDFFVKEGVLIPRPDTETLVEE
                     IIEICREKKDVSILDIGTGSGAITISLAKYIENSKIMSFDISETALEIAKKNAIINEV
                     GEKIKYINSDLFTAISDSNIKFDIIVSNPPYIKKQDIETLHKQVKDYEPYNALEGGED
                     GLDFYRRITEQGKKYLNKCGILAYEVGHNQAEDVINIMKSNGYKKIYTKKDIQGIDRV
                     VIGYNI"
     gene            75067..76131
                     /gene="prfA"
                     /locus_tag="OE968_000071"
     CDS             75067..76131
                     /gene="prfA"
                     /locus_tag="OE968_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HCP7217388.1"
                     /translation="MLKKLEVLEDTYKDLSEKIGDPDVINDQKVWQKYIKEHADLEPI
                     VMKYREYKSVLDSIKESKEILQEESDEELRELAKMELAEMEEKVAPLEEEIKILLLPK
                     DPNDDKNVIVEIRGGAGGDEAALFAGDLFRMYSRYAERRRWKIELLSASDTGVGGYKE
                     VSFMIKGKGAYSRLKYESGVHRVQRIPSTESGGRIHTSTSTVAVLPEVEDVEVEINPN
                     DLRIDVFRSSGNGGQSVNTTDSAVRVTHIPTGEVVSCQDGKSQLKNKEQALKILKARL
                     YDKALAEQHKDIAAERKSQVGTGDRSERIRTYNFPQGRISDHRINLTLYKLDAFLDGD
                     IDEMIDALITVDQTEKMTAI"
     gene            76260..76940
                     /locus_tag="OE968_000072"
     CDS             76260..76940
                     /locus_tag="OE968_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HCP7217389.1"
                     /translation="MILKVTIIGLLAGVIGTGLGGVISAIFKREVDKYLSFFMGLSGG
                     IMLAVVVFDLMKESMDKMGIINTVIFTFVGALITMYIKTKLDVSGNMASGYLIFISIL
                     LHNLPEGLAIGSSFMSTESLGITLAIVIGLHNIPEGLAMALGLVCNKMKLSKVILFTV
                     IAGLPMGLGSFLGVYFGGVFTSLIGVFLATAGGTMMYVVLEEIFPHSKSVYCIIGFLL
                     GTMIVNYI"
     gene            76969..78009
                     /locus_tag="OE968_000073"
     CDS             76969..78009
                     /locus_tag="OE968_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HCP7217390.1"
                     /translation="MKTIISNIDINNIDYEEIKIQAKLLREGKTVIFPTETVYGLGAN
                     ALDENAVKKIYEAKGRPSDNPLIVHIYEKEEVYDLAKDISDKAKLVIEKLWPGPITII
                     LNKKDIIPYKTSGGLDTVAIRMPSNVIARAIIKEAGIPIAAPSANISGRPSPTKAKHV
                     YEEMNGRVDGIVLGGDSNFGLESTVLDLTEETPMILRPGSITKEVLEELLGEVKLDPS
                     LSKKEDNQKAKAPGMKYKHYSPNADVYIISGKRENVATKINDMIKSNRDKGLKTGVMC
                     ISRNREFYDGEVIDLGNSLEEVASNLFDALIEMDKKGVDVIYSEEFPKTGVGQAIMNR
                     LLKSAGYKVIKA"
     gene            78026..78475
                     /locus_tag="OE968_000074"
     CDS             78026..78475
                     /locus_tag="OE968_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight protein arginine
                     phosphatase"
                     /protein_id="HCP7217391.1"
                     /translation="MNILIVCTGNTCRSPMAEAILRKAIKESGRSIEEYSISSAGIST
                     ANGMGASENSIEVLKEIGIDLSNHRSKVITKKLIDESDIILTMTKSHKEILVQAVPKC
                     KEKVYTFKGFANKNEEDISDPFGGNLDIYRSTMREIMYSVNEIVKKI"
     gene            78492..78944
                     /gene="rpiB"
                     /locus_tag="OE968_000075"
     CDS             78492..78944
                     /gene="rpiB"
                     /locus_tag="OE968_000075"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose 5-phosphate isomerase B"
                     /protein_id="HCP7217392.1"
                     /translation="MKIGLGCDHGGYNLKKEIISYLESKGIECVDYGTNNATDSVDYP
                     VYGEIVANSVINKEVDYGILCCGTGIGISLAANKVPGIRCAVVSDVFSAKMSKAHNDA
                     NMLSLGERVLGKGLALEIVEAWINTDFEGDRHARRVNMIKSIEEKHNK"
     gene            78980..79609
                     /gene="upp"
                     /locus_tag="OE968_000076"
     CDS             78980..79609
                     /gene="upp"
                     /locus_tag="OE968_000076"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HCP7217393.1"
                     /translation="MSKVVETNHPLIQHKLTLMRDKNTGSKDFRELLTEIAMLMGYEI
                     TKDIPLKDVEIETPIQKTSSKVVAGKKLAIIPILRAGLGMVDGLVSLMPAAKVGHVGL
                     YRDPETLKPVEYYCKLPQDIGERDIIVVDPMLATGGSAVAAIDLLKSKGAKSIKLANL
                     VAAPEGIAEVQKYHDDVDIYVASVDERLNEHGYIIPGLGDAGDRLFGTK"
     gene            79910..80725
                     /locus_tag="OE968_000077"
     CDS             79910..80725
                     /locus_tag="OE968_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EF2563 family selenium-dependent molybdenum
                     hydroxylase system protein"
                     /protein_id="HCP7217394.1"
                     /translation="MKNCIVVRGAGDLATAVIHKLHNSGFKVVALEIEEPLAIRRQIS
                     FCEAVYEKKVTVEGVECIFCNTEKEIEEVLSQHKVALIIDPKGEKLSKLNPIVLVDGI
                     LAKKNLGTTKDMAPLTIALGPGFCAGEDVDVVIETMRGHNLGRIITNGRAEKNTGVPG
                     AIKGFSKERVMHSQYDGIMENVCKIGDIVEKGDLLCYINNYEKKHEVRATISGVLRGL
                     LKDGAKVNKNLKILDIDPRKEEVKNAFTISDKARCIAGGVLEAILNNGIYPQN"
     gene            80951..81388
                     /locus_tag="OE968_000078"
     CDS             80951..81388
                     /locus_tag="OE968_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dCMP deaminase"
                     /protein_id="HCP7217395.1"
                     /translation="MRPSWDEYFMEIAEVVKKRSTCIRRQVGAVIVRDKQILTTGYNG
                     SPRNLEHCENIGCKRQELNIPSGERHELCRALHAEQNAIIQAAHNGISVDGATLYVTT
                     RPCVLCAKMCINAGILKIVYEGDYPDDMSTELLKEAGIELIKF"
     gene            81573..81800
                     /locus_tag="OE968_000079"
     CDS             81573..81800
                     /locus_tag="OE968_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AtpZ/AtpI family protein"
                     /protein_id="HCP7217396.1"
                     /translation="MSKRNTHTEIAKLFSLISQIGLMIVISILGCTFLGKFLDSKLNT
                     TPVLTIIFLLLGVGGAFSGVYKTLIVYTRRK"
     gene            81805..82191
                     /locus_tag="OE968_000080"
     CDS             81805..82191
                     /locus_tag="OE968_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase subunit I"
                     /protein_id="HCP7217397.1"
                     /translation="MDIKLLNQVRSVTKGIVIFDVVLIVLMLITSTLSKPVLLGLIFG
                     SIIAMLNFRLLAISLEKSVTFPAGKAQAYASAQYAVRLFIMAVVLIASATVPHLNIIG
                     TALGLLSTKFVILSKNFINKLKRKEA"
     gene            82194..82898
                     /gene="atpB"
                     /locus_tag="OE968_000081"
     CDS             82194..82898
                     /gene="atpB"
                     /locus_tag="OE968_000081"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HCP7217398.1"
                     /translation="MNQAHYYLIGNFKISETILVSWGIMAFLAIASYFLTRNLKKVPT
                     SKVQIFLEFAVGGLAKMVTDVMGKNTVKRMPYMIPYIGSLFLFFACSNLSPLLGLRSP
                     TTDLDTTAAWAMITFFMIYFAGVKFKGLSYFKELAQPLAIMLPINIIGELARPISLSF
                     RPFGNILGGTIIMGLFYQLLGFISSLIPGLSIPIGEILIPVPLHLYFDLFAGLLQAYI
                     FIMLTMVFISSAGELD"
     gene            82967..83227
                     /gene="atpE"
                     /locus_tag="OE968_000082"
     CDS             82967..83227
                     /gene="atpE"
                     /locus_tag="OE968_000082"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HCP7217399.1"
                     /translation="METAIVAAASAIGAGIAVATGIGAGIGQGIAAAKAAEAVGNQPE
                     AKGDITSTLLLGVAIAESSAIYGLVISIILLFVNPFFKYLGM"
     gene            83350..83847
                     /gene="atpF"
                     /locus_tag="OE968_000083"
     CDS             83350..83847
                     /gene="atpF"
                     /locus_tag="OE968_000083"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HCP7217400.1"
                     /translation="MEKALVGITWEFVFQIVNTFIIFLLLRKLLFKPVLNIIESREND
                     IKSDLVEGEKAKNEGLALKKEYESKINFAKDEGQEIIKQATIRAEQKSDDIVNTAKKD
                     ALDIKEKANKDIEQERQKVINEIKNDISNIALLAASKVIEKDLDKSKHEELIENFIKE
                     VGEAK"
     gene            83844..84389
                     /locus_tag="OE968_000084"
     CDS             83844..84389
                     /locus_tag="OE968_000084"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HCP7217401.1"
                     /translation="MINVIANRYAEALFQLGEEENSTDVLFKELEKVVDMMTKVSKDF
                     YKVLKSPLVSKSEKKNLVEIIFSKEVSSNIKNFLKVLVDKDRISYLEDIELAYKELLN
                     KKNNVIDGVAISAIPMSETDIKELEVKLSNKYNKNVTIENVVDKTILGGVLVRIGNEQ
                     IDGTVKTRLDKMKEKLSEVIS"
     gene            84406..85908
                     /locus_tag="OE968_000085"
     CDS             84406..85908
                     /locus_tag="OE968_000085"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003405060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HCP7217402.1"
                     /translation="MNLKPEEISSIIKQQIKNYENKVELTDTGSVLTVGDGIASVYGL
                     EKAMSGELLEFPGEIYGMALNLEEEVVGAVILGDDSEIKEGDIVKRTGRIVEVPVGEA
                     LIGRVVNSLGQPIDGKGPIAYTKTRPVESEAPGIIDRRSVYEPLQTGIKSIDSMIPIG
                     RGQRELIIGDRQTGKTSIVIDTILNQKGKDVICIYVAIGQKRSTIAQLVSSLEKGGAL
                     DYTIVVSATASESAPLQYIAPYAGAAMGEEFMYNGKHVLIVYDDLSKQAVAYREMSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDELGGGSMTALPIIETQAGDVSAYIPTNV
                     ISITDGQIYLQPELFYSGVRPAVDPGISVSRVGGSAQIKAMKKVAGTLKLAYSQYREL
                     AAFSQFGSDLDEDTKKRLAQGERIVEILKQGEHQPIKVENQVMIIYAVINNHLEDIPI
                     DNIARFESELYAFVDNNYPEISRKILGGEDFTHDLTDAINEFKEKFVVEV"
     gene            85936..86814
                     /gene="atpG"
                     /locus_tag="OE968_000086"
     CDS             85936..86814
                     /gene="atpG"
                     /locus_tag="OE968_000086"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F1 subunit gamma"
                     /protein_id="HCP7217403.1"
                     /translation="MAGAGIKAIKTRMGTVESTKQITKAMELVASSKLRKAKEKAEDS
                     REYFNTLYNTVKDIAQTTRGIRNEFLKEREVKNKCYVVVAGDRGLAGGYNSNVLKESV
                     SHMKGKKETVITVGKKAHEFFSKRNYNIAKDINSVEACGYEDATEISQTIIDLYKKGE
                     VDEVYIAYTKFKSALSQEVEILKLLPLVFEKDTDEQGMAVKEEKQNRSKVQYIPSAEA
                     VLSYIVPQFISGTVYGGILESFASEQGARRTAMESATDNANEMLSNLELSYNRARQSA
                     VTQEITEIVGGVEALK"
     gene            86827..88221
                     /gene="atpD"
                     /locus_tag="OE968_000087"
     CDS             86827..88221
                     /gene="atpD"
                     /locus_tag="OE968_000087"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HCP7217404.1"
                     /translation="MANVGKVVQIVGAVLDVKFDSEQSLPNLLNALVIKLGDKEIVAE
                     VAQHIGDDTVRCIAMSATDGLVRGMEVVDTGGPISVPVGDETLGRIFNVLGKPVDGKP
                     APKSAPKLPIHRPAPAYDELETTAEILETGIKVVDLLAPYLKGGKIGLFGGAGVGKTV
                     LIQELINNIAKQHGGISVFSGVGERTREGNDLYGEMSESGVINKTALVFGQMNEPPGA
                     RMRVALTGLTMAEHFRDEQGQDVLLFVDNIFRFTQAGSEVSALLGRMPSAVGYQPTLA
                     TEMGALQERITSTKKGSITSVQAVYVPADDLTDPAPATTFSHLDAKTVLSRQISSLGI
                     YPAVDPLESTSRILDPSIVGKEHYEVARGVQSILQRYKELQDIIAILGMDELSDEDKL
                     IVARARKIQRFLSQSFTVAEQFTGNPGQYVPVKETVRGFKEILEGKHDDLPESAFLFV
                     GTIEDAVRKAKGSM"
     gene            88224..88484
                     /gene="atpC"
                     /locus_tag="OE968_000088"
     CDS             88224..88484
                     /gene="atpC"
                     /locus_tag="OE968_000088"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F1 subunit epsilon"
                     /protein_id="HCP7217405.1"
                     /translation="MASEFSLKVVTPSNTFYDGDVEMIVVRTTKGDKGVLKGHIPFVS
                     GIPVGTLKIKKEGSFKEAKIAEGFINVTQDKTVILTESAEWI"
     gene            88946..89326
                     /locus_tag="OE968_000089"
     CDS             88946..89326
                     /locus_tag="OE968_000089"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HCP7217406.1"
                     /translation="MNIFDIGVDIIEIDRIRKAVDKNNRFLEKIFTDREIEYFNSKNF
                     KAESIAGNFAAKEAISKSIGTGIRVFNFKDIEVLRDEMGKPIVKTYNNLAKMCIDYNV
                     LEIKVSISHSKDYAIANAITIIKD"
     gene            89341..89802
                     /locus_tag="OE968_000090"
     CDS             89341..89802
                     /locus_tag="OE968_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HCP7217407.1"
                     /translation="MMDKTAKEIMTTDVIVAKQDDSIADVANMLIAEKIGGLPVVDSE
                     NRVVGIISETDILKKEKYIEAPLYINLLQGLIFLDDLKKVEKDIKQVAAYKVGELMSK
                     DIIKVHEDDKFDDVANVMIKKSINRVPVVDDDNKLKGIICRYDIIKALYNE"
     gene            89823..90413
                     /locus_tag="OE968_000091"
     CDS             89823..90413
                     /locus_tag="OE968_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7217408.1"
                     /translation="MRKKWTIVCIMFLALVIIVIGCQKRQSTKEEVYKDFQKQISDMN
                     YYSCKAEVEVVGNKSPHNYVLIHTYKKTDNYKLEVISPKHLKGKSIEYQGDKILVKNP
                     KISDVVELPNTGKNNQYLFVGDFIKNYLQNEEMKVKLSKGHLVLETFIPGDNKYFNKQ
                     VLYVNADTKNPEKMEVLDKEGVPRFTVKYKDFEYRN"
     gene            90428..91585
                     /gene="alr"
                     /locus_tag="OE968_000092"
     CDS             90428..91585
                     /gene="alr"
                     /locus_tag="OE968_000092"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HCP7217409.1"
                     /translation="MQKITVPTWAEINLDNLRFNLNNIKNLLEEDIKICGVIKADAYG
                     HGAVEVAKLLEKEKVDYLAVARTAEGIELRQNGITLPILNLGYTPDEAFEDSIKNKIT
                     MTVYSLETAQKINEIAKSLGEKACVHVKIDSGMTRIGFQPNEESVQEIIELNKLEYID
                     LEGMFTHFATADEVSKEYTYKQANNYKFMSDKLDEAGVKIAIKHVSNSAAIMDCPDLR
                     LNMVRAGIILYGHYPSDDVFKDRLELRPAMKLKSKIGHIKQVEPGVGISYGLKYTTTG
                     KETIATVPIGYADGFTRIQKNPKVLIKGEVFDVVGRICMDQIMVRIDKDIDIKVGDEV
                     ILFGEGEVTAERIAKDLGTINYEVLCMISRRVDRVYMENNELVQINSYLLK"
     gene            91618..91905
                     /locus_tag="OE968_000093"
     CDS             91618..91905
                     /locus_tag="OE968_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribbon-helix-helix protein, CopG family"
                     /protein_id="HCP7217410.1"
                     /translation="MYDKSKEKIEVTLPDSLISEVDSIVQMENSNREDFAKAAFQFYI
                     TQKKKIHIKESMKTGYREMGQINLSLAELGMTVEEVSSDDKNEGKIAQGEY"
     gene            91874..92257
                     /locus_tag="OE968_000094"
     CDS             91874..92257
                     /locus_tag="OE968_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HCP7217411.1"
                     /translation="MKGRLPKVSTNCEIKRGDLYYADLSPVVGSEQGGVRPVLIIQND
                     VGNKYSPTVIVSAITSQINKAKLPTHVEISSNEYGLNKDSVILLEQIRTIDKKRLREK
                     IGCLDENMMIKVDDGLQISLGLFTF"
     gene            92428..93255
                     /locus_tag="OE968_000095"
     CDS             92428..93255
                     /locus_tag="OE968_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HCP7217412.1"
                     /translation="MRDHKGLNEIARIIRRDIVSMIHRAKSGHPGGSLSVVEILTALY
                     FDEMNVDSSNPKMEDRDRFVLSKGHAAPALYATLAEKGYFDKEELNGLRKIGRMLQGH
                     PDMKGTPGVEISTGSLGQGFSVACGMAMASKLDNAPWNVYTLLGDGEVQEGIVWEAAM
                     SAAHYKLDNLIAFLDNNGLQIDGDIESVMSLGSIVDKFKAFGWNVIEIDGHDFDQIFA
                     ALDIAKSTVKKPTMIVAKTIKGKGISFMENQAGWHGTAPSDEELEKALLELGGADNE"
     gene            93248..94189
                     /locus_tag="OE968_000096"
     CDS             93248..94189
                     /locus_tag="OE968_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HCP7217413.1"
                     /translation="MSKMATREAYGKALVKLGQINDNVVVLDADLSKSTKTHDFYKSF
                     PDRFFNMGIAEQNLIGAACGLSTAGKIPFASTFAMFATGRAFEIIRNSVCYPKLNVKI
                     CATHAGLTVGEDGASHESVEDIAIMRAIPNMTVLVPADGVETEKIIFEIAKYNGPVYV
                     RLGRSSVPVLFDEDYKFEIGKGTVLREGKDVSIIACGIMVNEALLAQEKLQEEGISAR
                     VINMSSIKPIDKDLILESAKETNAIVTVEEHSIIGGLGSAVSEVVGESCPTIVKKVGI
                     KDTFGESGTPNELLKKYELTCDDIIKTVKEAIIAKRM"
     gene            94612..95706
                     /locus_tag="OE968_000097"
     CDS             94612..95706
                     /locus_tag="OE968_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7217414.1"
                     /translation="MSEKVNVKTVISFAGAYVATVIGSGFATGQEIMQFFSFYGFAGI
                     IGGIISMVLFSWMGASVMSKGKELQLKEPIKIYRVYCGKYLGIFFEWFGPLFLFGVFV
                     VMISGAGATLTEYYGLNPFVGRVGMAVVALLTVSLGLDKLSKILGGIGPIIIIFTLLV
                     GGISLAKNIGNIGEAAQVLSTVKIAKPVPNAYLSGVIYTTYNTIVVMAFLTGLGASAA
                     NKKEAICGGILGGVALMAAAIMMHLAILSDIGNLYSKAIPSLFLADKISPVIGVLFSI
                     ILILGIYTTAVPLLWSVTNRFVDDKHPKFKLITLIAAILGLIGGFLPFDKLVGILYPY
                     TGYMGVIILVCVLYRQITKTSGYQEGISDK"
     gene            95932..96348
                     /locus_tag="OE968_000098"
     CDS             95932..96348
                     /locus_tag="OE968_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7217415.1"
                     /translation="MNVKFNIKGIIYGVIALVFVIGGFIFIPSMFVEKSKPIDYTVLQ
                     RNSIPEKILDVMDKYTNEERALAAKIDNKIYIIVTRGNNKYGIEMDKIESVVEEGKDV
                     LRVKIKYKDKEDSFPYIVVETNMSELPDRIELNATK"
     gene            complement(96530..97099)
                     /locus_tag="OE968_000099"
     CDS             complement(96530..97099)
                     /locus_tag="OE968_000099"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HCP7217416.1"
                     /translation="MKKEFRKKVIESRKNKNANFVLSNSNLITEKLLQMEDIRNATNI
                     MLYLNFNNEVQTDNLIKKLLSLKKIVSSPITIKENHTLIPTQITDLKEGLRIGAYGIR
                     EPNEKSPTIDIKALDVVIVPAVAYDIHCYRLGYGGGFYDRFLENLRKDAITIGIAFDF
                     QIFDSIPKETHDAQLDYIVTETRIITPNS"
     gene            97253..98410
                     /locus_tag="OE968_000100"
     CDS             97253..98410
                     /locus_tag="OE968_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S41 family peptidase"
                     /protein_id="HCP7217417.1"
                     /translation="MYLVISKKKAIFLGVILVIITAMVTSAFQLTLGNKVVISKELYE
                     DYKKYDKLLGLESIIKQDFYKKVSDTDLVNGAAKGLFLGTNDKYSGYYTKDEMENLIN
                     DSEGSYVGVGMYIGASKDGGLVVVPMKDSPAEKAGVKSGDKLVKVNGKSVSYKNSDEA
                     VRMMKGKKGKTVELTILREDKQLNFKVKTDQIIEKSIESKVIDNDLGYIEITQFISST
                     YTDFDKALKELKAKNIKGLVIDLRNNPGGMLDICKEVADELIGEGTIVYTKDNKGNTE
                     YLKSDKEKLGLPIVVLTNGESASAAEILTAAIVDNKEGISVGTTTFGKGLVQSVVRLK
                     DGTGYKLTTAQYFTPNGDYINEKGIKPTIEEKDENKQLDVATKWLREQIDK"
BASE COUNT        39574 a        10666 c        18137 g        30452 t
ORIGIN      
        1 ttaaaaactt aatagaaata ttaagcataa agattatgtg gttacaatag cagagaggat
       61 acacctgttc ccattccgaa cacagaagtt aagctctcta gcgctgatgg tacttggtgg
      121 gaaactgcct gggagagtag gacgtagcca cgtaattttt tttatttttt gtcaaaaaaa
      181 acaaaaaata cgtatttctt ttttcatttc gggaaaacta aacacaggaa ttatggactt
      241 tataaaaatt taattcttga ggagtgatat aagtgaaaaa agttgcttta attttagcta
      301 taataggtgc gcttaactgg ggtgcaattg gtattctagg tacagactta ataggtagta
      361 tctttggtgg aacatatgaa atggtaagta gaataatata cttcattgta ggtttagctg
      421 gattatactt aataccaagt ttaatgtctg atgatagaga ataatttatg cttttatgtt
      481 aaatacctca ttctaaatgt ttagaatgag gtatttaatt ttataaaaat attaatttgt
      541 ttctttttta atggtaaaat agataagaat tgaagtttta aaaagaagta ttatgtaaaa
      601 aaggagtact attaatatat gtttattatt aatgaattaa ataagattgt aaatgaagaa
      661 gtaatatctt ttcatatgcc tggtcataaa aagggacagg tttataaaaa gttaggatat
      721 aaagatatac taaaaaattt gtataaaatg gatacaactg agatattagg aacagataat
      781 ttacactttc cggaaggaat tataaaaaat tcacaaaaaa aagcatcaag agtatttaaa
      841 agtgattata cttgctattt agtaaatggt agtagctgtg gaatacaatc tgcaataatg
      901 tcagtatgta gtcctaaaag taaaataata acaaatagag actgtcatca gtctgttata
      961 aatggatgta ttttaggaga tatagatata gagtatgtgc cttgtgagat aagtgaagag
     1021 acaaatatct taaaagggat atctataagt aatgtgattg atataataga taaaaacttg
     1081 gatgcaaaag cagtactgct tacttatcct acatattatg gaatgacata tgatttagaa
     1141 tacatatgta attatgcaca tagcaaaaag atggtagtga tagtagatga agcacatggt
     1201 gcgcatttag ggcttagtga gaggcttcct aaaacagctc ttgagcaagg tgcagatata
     1261 gttgtacaga gtacacataa aactcttcca gcatttacac aatcgtcaat gatacatata
     1321 cagggagacc gagttgatat agataaaata ttgaacatgt taagaattac agaatcttca
     1381 agcccttcat atttattatt atcttctctg gaattagcag tagatatata tgaaaataaa
     1441 ggaaaagaat taatggaaga gcttttaaat aatattataa ctttcaaaaa taaagttgat
     1501 tcaaatatta atatatacga cacaaatgat aaaacaaaaa tatttatatc atctaaaaac
     1561 atgggtttaa caggttatga actagaaaat attttgagaa ataaatataa catacaagtg
     1621 gagttatcta attattatgg agttctttta atatgtacaa taggaaatac tgctgaggat
     1681 ttctctagtt tagaaacagc attaaacaat gttgtaaagg aagactttaa atttgaaaag
     1741 ttagaaaata aaaaataccc tgttgttatt ccaaagaaaa tattaacacc tagagaagca
     1801 ttttataaaa ctaaaaaaag tgttaaaata tatgacagta taggtaaagt ttgtggtgaa
     1861 tgtatagttc catacccacc tggaataagt gtaatatctc ctggtgaagt aataagtaaa
     1921 gaaataatag actatctaat gttttgtcat tctaaaggca tgattgtgag tggattgaaa
     1981 gatgtagatt taaattttat acaagtaata gatttagaag acatttaaaa attatgatat
     2041 aaaagtagat agaagtagat agtttaaaat tgtgaagaga aataaataga ctgcttatat
     2101 agagatatct aataaaagta ctaaaaaagt aaaaagtgtt tgtatggagg atatgaaaat
     2161 gaaaggtaag ttaataatta tagagagtgg ttcagatgca agtggaaagg ctactcagac
     2221 agaaatatta tatgaaagat taaaaaaaga aggctatatg attaaaaagg tagaatatcc
     2281 aaattatgaa tctccatcat ctgccttggt gaaaatgtac ctaaaaggag actttggtaa
     2341 aaatgcatca gatgtagacc catatatagc atcaactttt tttacagctg ataggtatgc
     2401 atcatttaaa accgattggg aggagtttta caatgaaggt ggaataatta tcgcagatag
     2461 atatacaacc tctaatatgg tacatcaggc ctctaaaatg gatatttgtg atagagaaga
     2521 gtatttaaat tggttagctg attatgaatt taatttattt aagataccac aacctgattg
     2581 tgttatattt ttagatgtgc ctattgaatt tagtaaaaag cttatggaga atagaaaaaa
     2641 taaaattaca ggggaagaaa aaaaggatat tcatgaaagt gacatagagt atttagagaa
     2701 atcttacaac aatgctttat atatagcaga taaatatgat tggaaaaaaa taaattgtgt
     2761 tttagataac aaattaagaa gtattgaaag tatacataat gaaatttata aaatagttct
     2821 tgattcaata aaacctatgg agagataaat atgtattttg aaaatattat agggcaagat
     2881 tttgcaaaga aatatttaac aaattctata aagaaaaata aacttaataa tgcgtatatg
     2941 tttgaaggaa tggatggaat aggaaaaaag aaatttgcag atgaattatc aaaactatta
     3001 cttgattatg aaaatctcga aaatagtcca gactatgtac tcataaaacc agatggaaat
     3061 agtataaaaa tagctcaaat cagaaattta caatcagata tagtaataag acctcataaa
     3121 gactataaaa tatatataat caataatgct gaaaaaatga ctgtggaagc tcaaaatgca
     3181 cttttaaaga cgctagagga acctccaaac tatgctataa taatcttagt tacaaacaac
     3241 aaggaatctt tattagaaac tataaaatct agatgtgata taataaagtt ctcacctata
     3301 ccaattgaag acttaaaacg ttatttgata aatacaggta tagaagaaga aagagctcaa
     3361 ttattggcta ttttttcgag aggaagtatt gagaatgctc taaatctatc tcagtcttct
     3421 gagttttcaa tgatgagaga agatatacaa cagtatattc agataatgtt agataaaaac
     3481 atagtggaga ttttaaatat accaaataat atggaaaaat atagaggtaa gattatagct
     3541 ttattagata tgatgataaa ctattttcga gatatcatcc tattaaaaga aaatgtaaac
     3601 aagaacatgt taataaatgt agataagcta gttttcattc aaaatatgaa tggaaaaatt
     3661 agttattctc aattgtccaa gattattgat ataatagaag atgcaaagag taaaataaaa
     3721 agcaattgca atttcaatat aagcatacaa gttatgtctt taaatatata cgaggtgatt
     3781 aaatgataaa gatagtaggt ataaggttta aaagtgctgg gaaaatatat tattttgacc
     3841 ctgttgattt taatatagag caagatatgg atgtagttgt agaaactgca agaggcttgg
     3901 agtatgggaa agtagtcgtt ggtccaaaag atatggatga aagcgaatta gtttctcctt
     3961 tgaagccaat tataagaata gctacagaag aagataaaaa agtatatcta gaaaataagg
     4021 aaaaggcaaa agaaactttt gagttgtgcc aacaaaaaat aaaagaacat gagttaacaa
     4081 tgtttttaat agattgtgag tatacatttg ataggaataa gttgattttt tactttacag
     4141 cagaaggaag aatagatttt agagaattgg taaaagactt agctgctata tttaaaacta
     4201 gaatagaact tagacaaata ggtgtcagag atgaagctaa atctatagga ggtctagggc
     4261 cttgtggtag aaaactttgt tgttcatctt ggttaggtga ttttcaacca gtttcaataa
     4321 aaatggcaaa agaccaaagt ctatctctaa atccaacaaa aatatctgga atatgtggga
     4381 gattattctg ttgcttaaaa tatgagcatg atgtatatag tgaagcaata gaaaaaatgc
     4441 ctgttgtagg tgcattggtg caatcagatg atggaaaagg aaaagttgta gaagtgaatc
     4501 ctttattaga acaaattaaa gtggaatttc aagacaagac agtaaagata tacacaagag
     4561 aagatataaa aatacttaga gagcctaaaa aatgtgatgg ctgtggtggt aaatgtaagg
     4621 ataatgatgg attagatgaa gccacactaa gagagctaaa gaaattagaa gattaaattt
     4681 aaggtagggc ttttcctacc ttttttaaag caattaatgc ttaaagttat taatatttga
     4741 ggagaattta tatatgcaat taaaagattc agaaagaata gatgatttac aattaaaagg
     4801 ccttaaaatt atacaagata ctaatggttt ttgttttggt atagatgcag ttttattagc
     4861 caattttact aaaataaaaa aagatgccaa agtagtagat ttgggtactg gaactggcat
     4921 tatacctatt ttgatagctg gaaaaagtga agctaaaaaa attattggcg tggaaataca
     4981 agaagatgta tatgaaatgg caactcgttc tataaaatta aatggattag aagaaagagt
     5041 tgagattata aatgaagata taaaatacat agacaaagtc ttagacataa atggttacca
     5101 tgtagtcaca tcaaatcctc catatatgca tattgatgga ataaaaaatc caaatgataa
     5161 aaaagcaata tcaagacatg aagtaaggtg caatttggaa gatgtaatta gagctgcatc
     5221 cagattggtt atgcctagag gaaaattctt catgatacat agaccaacaa gattggttga
     5281 tataataact ttagggagaa aatataaatt agaaccaaag gttattcaat ttgtgcatcc
     5341 aagacctcaa aaagcaccga acttagtttt ggttcaattt gtaaaagatg gaaggccaga
     5401 gcttaaaata ttggacccat tgtatgttta tggagaagat gggaattata caaaagaatt
     5461 aaaagcaata tataataata aagatatagg agagttgtaa atgagcggga aattgtacat
     5521 atgtccaaca ccaataggaa acctagaaga tataacatat agaactttaa gaatattaaa
     5581 agaagtagac ttgattgcag cagaagatac aagacatagt ataaaacttt taaatcattt
     5641 tgaaatctca aaaccactaa ctagttatca tgaacataat aaggattcaa agggagatta
     5701 tttgataaat aaactaattg atggtgaaaa tatagctctg ataagtgatg caggtatgcc
     5761 tggtatatct gacccaggag aagagataat aaaacaagct atacaaaata acatagagat
     5821 agaagtattg ccaggtgcaa cagcctttgt aacggcttta gttggctctg gtatggacac
     5881 acatagattt atttttgagg gctttttaga tagagataaa aaagttagga aagcacaatt
     5941 ggaagaatta aaggaagaaa gtagaactat aattttctat gaatcaccac atagattgaa
     6001 ggatacacta aaagatatgc ttaaaattct tggtaatagg aatatttcta taaatagaga
     6061 acttacaaaa aaatatcaag aaataataag agaaaatata gaaactacca taaaaatatt
     6121 tgaggaaaaa gaagtaagag gagagtttgt attaatagta gagggttttc atggtgagaa
     6181 gtcaaagaaa gaaaattatg atgggcttac agatagggaa tatgttttaa aactaattga
     6241 aagtggtatg aacaaaaaag atgcaataaa aatagtttgt aaagatagaa agttaaagaa
     6301 agatgtggtt tataaacaag ttttagattt ataaaacctg aatctgaggt gattttatgg
     6361 aaatagggaa aattataata gagagtttaa agagggaaga tacacataaa atatttatag
     6421 aattagataa taagcatgaa ttagaaaaaa taattcctaa aataagctgt atgaagtctg
     6481 taggtgaatg taaatatcat gtagtaaatt gttttgaaca ttctataaat gcattaaaag
     6541 aattagaaat agtattaaat gataaggatt tttttccaat acatctaaga aaacatgtgt
     6601 caaactattt aaaaacatat attgaagaag gaataaataa gttacatgta ttaaagctgg
     6661 gaacattttt acatgatata ggtaagcctg acagtatgac cttagatgaa accggaagag
     6721 ttcatttcac aaatcatgaa aaaataggtg ctcaaataat tgacaatatg ggaataaagt
     6781 tagagttatc aacagagaca tatagactta taagtaaata tgtaagatat catatgatac
     6841 ttttgtctct atataagaaa aatgatttga gtaggaaaga attaattaat gtatttaact
     6901 tagtagatga ggacactata ggtgtaataa tgcttgggta tgcagatata gtgtctacag
     6961 taaaattatt gggcaagagt ggagaagtca gtgtgttaaa gacatatatg gaatatattt
     7021 taacaaatta cttgtataag agtaattata cacatgtata aatttagtta atataattga
     7081 gttttagatg attaattgaa gtttgaaata tacggatttc aaaaacataa aagaagttgt
     7141 ctttgttgta aaattatgaa agacaacttt ttttatatca aaaattgaaa ttttattaag
     7201 gatacttaat ggtctattaa ttaataaacc attagtattt aatttatatt acaatattga
     7261 ttttgcttgt attggcgttg atagtataac agaggtctta gtagaaccaa ttttctttat
     7321 agtatcaatc acattttcta gctcgtacat atcttttaca attactttta aaagtaagca
     7381 atcatcacct gttatatggt gacattctac aatcctaggg tcctttgcag ctgactcaat
     7441 aaattctgta tatccattgc ttggaagaga aatatgaata aatgccttta taactctgcc
     7501 taatgaatct gggttgacaa tagctttata tccttctata acaccagact cttctaatct
     7561 tttgactctt tctgaaactg caggagaagt taaaccaact atttttccta agtccttcat
     7621 agaaattctc ccatcatcct gtaaaatttc tatgattctg taatctgtaa catccataaa
     7681 taaacagtcc cccttaaata aaaataatta atgctataaa acttttttag aatctatcat
     7741 ttgtgttttt aaataccaaa gatttctaga taaatcaacc ttataaatgt gtggttttga
     7801 aagtcttttg tattgttccc agatagtact taattcatat tgtacatgat tttttatttc
     7861 aagaacagct tttttattat atttgcatct gccttttata tacaatggtt taagaagctc
     7921 tttaactttg taatttgtaa ataccttcgt tttccatgta taagtaggat ggaagatttc
     7981 taaaggttta gactcatcta taacttcatc atgtaacata atcaaatctg cctctgcctt
     8041 attgtcttcg ttatatattc ttataacttt cttgtaacca ggattattta ttttttctgg
     8101 attctcagaa atctttatct taggttcaag aactcctttt tcacaagatg cagctaattt
     8161 ataaactcct ccaagagaag gtgaatcgaa agatgtaatg agctttgtac ctactcccca
     8221 tgaatttata gtagctcctt ctgctttaag tgatgttatg gtatattcgt ctaggtcatt
     8281 agatgcagtt atgctgatat ctgaaaagcc agcattatct aattgttttt tagcttcttt
     8341 agataaataa gctaaatctc cagagtcaag tcttataccc ataggtttgt atcctttttc
     8401 agaaatattt ttgaatactt ttattgcatt aggaactcca ctgtttaata catcataagt
     8461 atctacaagt agtaggcatt tatctggata aacatcagca tatgcttgga atgcttcaag
     8521 ttcattatca aatttttgta cccaactgtg agcttgtgta ccaattatag gtatatcaaa
     8581 cattttccct gctagtacgt ttgcagttcc agcacaacca ccaactacgg cagccctagc
     8641 cccatatatc cctgcatctg gaccttgtgc acgacgtaat ccaaattcaa atacagggtc
     8701 tccttgagct gcaaagcaaa ctctagatgc tttagtagca ataagagact gaaaattaac
     8761 tattgttaac aatgctgttt caataagttg agcttgatat aaaggtgcct taacagtaat
     8821 taatggctca ttagggaaca tgatagttcc ttcctcaaca gcatatatat ctcctgtgaa
     8881 tttaaattct tttaaaaatt ttaagaactt gtcagaaaat aaatttaagt tttttaagta
     8941 ctctaaatct tcatctgaaa aatgaagatt atctatgtat tcaacaacct gatcaatacc
     9001 acaaactata gtataccctc catcacaagc gttttttcta aaaaacatat caaatacaac
     9061 aatgtcttca tgaatattct tttcaaaata gccatttaac atagtaagct gatataaatc
     9121 agtaagaagt gttagatttc tcattatttc tctccttaat tattattaaa tattaaaaat
     9181 tgtaaaaact cccacactta tactaaaaca taatatagta caactttcaa gtataaagta
     9241 ttacctaact atcataaaat tatttaaaga ggaggatgat tataatagga aaaatatggt
     9301 tttatatggt atcgatagga ataataggaa gcttgatttc taaaaatatg ggtgaattaa
     9361 ataaagttat attaagtgaa acatcaaaag gtatagagtt tgcaataagt ctagctggta
     9421 tcatggcact ctggatgggg ataatgaata tcgcaaaaga atcaggttta attgaaaaga
     9481 taggtcaaaa actaaatcct ataatgagaa gattatttcc ttctattcca aaaggtcata
     9541 aagcaatgtc ttatatagtt atgaatattg ctttaaatat gttgggtgct ggaaatggtg
     9601 caacagcatt tggtttaaaa gcaatgagtg agcttcaaac tttgaataac aagaaagata
     9661 cagccactaa tgatatgatt atgtttatgg taatcaatat atcatctata caaataattc
     9721 catttactat aatcaaacta aggatggata tgggggctca aaatccaagt gaaataattt
     9781 ttacgacttt atttgcaacc ataatatcta cagcagtagc aataataaca tgtaaatttt
     9841 ttcaaagaag atatagataa aggggatgta gatacatgga gatattttca aacttactta
     9901 taccaataat aattctgtac atagtagttt atggtaaata taaaaaaata gatgtgtatg
     9961 atagttttgt aaaaggagca attgatgggt taaaagcagc atgggatatc ctaccatata
    10021 taataggtat atttttggca ataggaatat tcaaaactgg taaaggtctt gatatgttag
    10081 aatggctatt tacaccaata gcaaatatga tgagtatacc aaaagaatta ataggtctaa
    10141 taagtgtaaa acctttatct ggaagtggtg ctttagggat gtacagtgaa cttgcaaata
    10201 gagttggaat aggaagttta gtagaaaaaa tgggtgctac gattgtaggt tcttctgaga
    10261 ctatttttta cacaatggca atatactatg gaagtctgaa gataaaaaat actagacata
    10321 cattatcatg tgctatgatt agccatgttg caggtgtcat agcagctgtt tttatttgct
    10381 atgtaatatt tgtataattt gttgacaata tgggaaaaat tttataatat agtgattata
    10441 tagaaacaaa tagtaataca aattacaagc tatgaaaaga agagtaaata aaggtttttt
    10501 ctatcagaga gctaggttag gtgaaagcta gtgtcaaaag ctttattgaa gatggtcttg
    10561 gagcttttta tctgagcaag tgtgctaggg taaaacggtt ggacacgtta tagtctacta
    10621 aggtatctat aaaatgtttc tacatttcat gtgaaacata actattatag atgaattagg
    10681 gtggtaccgt gaataatctc gcccctatgt taactcatag gaggcgattt tttattattt
    10741 aaatgaaaga atcatatgat tacgaacgat aaaaaattag gaggtaaata acatgagcaa
    10801 accgagtttt tatgtaacaa caccaatata ctatccaagt ggaggattac acataggaca
    10861 tacttattca acagtagctg cagatacaat agctagattc aagcgtttct gtggatatga
    10921 tgtaaagttc ttaacaggaa cagatgagca tggtgaaaaa attcaaaaga aagccataga
    10981 acaaggaatg tcagagatag agtatcttga tggaatgata aaagatataa aggccttatg
    11041 gaatactatg gatatatctt atgatgattt tataagaact acagaaaaaa gacatacaga
    11101 cataatacaa aagatattta ctaaactata tgagcaaggt gatatatata aaggtgaata
    11161 tgaaggtaga tactgtactc cttgtgagag tttctggaca gaatctcaat tactagaagg
    11221 aaataaatgc cctgactgtg gaagagaaac atatttagta aaagaagaat cttatttctt
    11281 tagattatct aaatatgaag acagattaaa agagttattt aaagatgata gtttctgttt
    11341 tcctgctgct agaaaaaatg aaatggtggc aaacttttta gacaaaggat tagaagattt
    11401 aagcgtaact agaacgactt ttgactgggg tataaaagtt ccttttgatg aaaaacatgt
    11461 aatttatgtg tgggtagatg ctttatgtaa ctatataaca gcattaggtt atatgactga
    11521 taatgatgaa gaatttaaaa aatattggcc tgccaatgtt caaatagtag gtaaagaaat
    11581 agtgagattc catacaataa tatggccagc gcttttaatg gctttaggtc tagaagttcc
    11641 aaaacaagta tttggacatg gatggatact atttgctgat gataaaatga gtaaatcaaa
    11701 aggtaatgtg gtttatccag aacctataat agaaagatat ggaatagaca cacttaagta
    11761 cttcttatta agagagtttg catttgggca agatggaagt tatactcata gaaattttgt
    11821 aacgagaata aattatgatt tagcaaatga tttaggaaac ttaataagta gaactgtagc
    11881 tatggttgaa aaatacaata atggtataat accaacagca aaagtttcaa ctaattttga
    11941 tgctgactta aaagaacaag ctgtttcaac tagagaaaac tttgaagctg aaatggataa
    12001 aatgcaattc catgaagcat tagagagtgt atggaaatta gttagaagaa ctaacaaata
    12061 tatagatgaa actatgcctt gggcactagc taaagatgaa actaagaaag atgaattaga
    12121 cacagtttta tataatttat gtgaatctat aagaataatc gcaacactaa taaatcctat
    12181 aatgaatgag actgctaata aaatatatga acatatagga ataaaaggtc aagatgatat
    12241 aactacatgg gaaagtacaa aaacatttgg tcttattgga gaaaatgtaa aagtatttaa
    12301 aggtgaacct ttattcccaa gattagatgt agaaaaagag atagaagaat taactaaaat
    12361 gttctctggg aaacctccag tagaagaaaa acctttagag cataaagaag aaattactat
    12421 tgatgattta gacaaaatag agcttagagt agggaaaata ataagctgtg aaaaacatcc
    12481 aaaagcgaat aaattattag tatcacaagt taagattgga ccagaaacaa gacaaatagt
    12541 atcaggaata gctgaatact ataagccaga ggatttagta ggaaaagagg ttacagtggt
    12601 atgtaactta aaaccagtta aattaagagg tgtagaatct caaggtatga tattagcagc
    12661 aggtgatgat ggagacccat atgttttacc atttacacaa ggggctaaag atggatgtga
    12721 ggttcgttag taggtaatta aatagtaagg agattaaaga tgttatttga ctcacatgca
    12781 catttaaatg atgaaagttt tgatgaagat agagatgaac ttattggttc attaaaagat
    12841 aaaggtgtag atttggttgt aaatccagga gcagatatag agacgtcgat aacagcaatt
    12901 gaacttgcga aaaaatacga ctttatatat tcagcagttg gggtacatcc acatgatgta
    12961 tcaaaactag atgatacagc aatagaaact ctaagaaaac ttgcaactga gaatgaaaaa
    13021 gttgtagcta ttggagagat tggattagat tattattatg attattctcc aagagaagaa
    13081 caaaaagagt ggtttaagaa gcaaattgaa ttagctaatg agctaaaact tccaataata
    13141 atacatgata gagatgcaca tggagatact tttgagataa taaagaatac taaaaatcct
    13201 gaaataggat gtgtacttca ttgttatagt gggaatgtag agttagctag agaatatgtt
    13261 aagatgggtt gttatatatc aattccaggt acggttactt ttaagaataa taaaaaaact
    13321 agagaagtag taagagaaat acctctagaa agattattca tagagactga ttcaccatat
    13381 atgtcaccag agccacatag aggaaagaga aacaatcctt ctcaagtatc ttttgttgct
    13441 gataagatag cccaggaaaa agggatatct tatgaagaag tatgtagagt tacaaaagaa
    13501 aatgcaaaga aattttttaa tataaaatag acaaattaaa tcttataatg atatatataa
    13561 taagtcatta taagtatagg atgagagtgc ctcaaaatga gttttttagt ttatgaggca
    13621 ctctttttgt atgaaatcaa atatattttc atcatttcaa caatgaaaaa gaagtttatc
    13681 atattttgag atagtttgtt tttatttatt taattcatat tttaaaatat attttcttaa
    13741 cattgttaaa aaagaattta caagatattc attagaatta actcaactct aatattcact
    13801 taacttaagt tgtttattat attattaaag agaagtaaac gaaaagtaga ttaaggaggt
    13861 tgaattttgt atacagttga tagtactaag atattgataa atatgaactt agagaaacta
    13921 gaaaagatat actcaatgat aaaagataca tcaagtattt ctataattaa agaacctaac
    13981 ttggctacag taatggtaag agctaatgaa agtgtaaaaa acacaacatt taatttagga
    14041 gagatattag ttactgaatg tagtgtaaag gtagatgaaa gcttgggtta cggaatagtt
    14101 tcagaaaaca ataataagaa agccatttat ttagcagtta tagatgcagt tttacatagc
    14161 aataacagta aatttgatga gttaaagaat tacataaata aaagtgtata tgaagagaac
    14221 ttaaggtatg aacaagagat tattgatgaa tttagcttga ttaataaaac gaaagttcaa
    14281 ttcaatgcta tggattaaat aggaggagaa tcatggtaaa ttatacacaa gaaatatata
    14341 gaaagatgct agatagtgct tcatttcctg ggaaattaaa taatatagat aatataaata
    14401 tagaaaataa tacaaaacta ttgaatggag caattggtat agcaatcact ttattagacc
    14461 aagaagttac cttctatata gaaaattata ctcaaaaaga tataaaaaat ataagagcac
    14521 ttacaatgtc aaatcaaata gattatagaa aatcagatta tatattttta gatattaatt
    14581 cagaagtgga tatattacag attaaaatag gttcttttga atatcctgat gaaagtgcaa
    14641 ctatagtaca tcaagtaaat gatttatcaa cgtactctca aactaagtat ataaagcttg
    14701 atttgagtgg tcctggtata aaatctaaaa atagtatata tataaatgga attagagaag
    14761 aatttataga aagattatct agcataaata aagattatcc aataggaata gatttgattt
    14821 tagtagataa aaaaggagaa attgcattta taccaaggtc atcaaaatta agttgggagg
    14881 tattatagaa atggcttatg tagcagttaa aggtggagaa gaagccatat tacaggctaa
    14941 aaatatactt gagttttata gggtaaaagg agatagcttg cctatagatg taaagcagat
    15001 tgaggaacaa atgtcttatg ctgtagacaa agtaatgtct gaaggaagtt tatacaacaa
    15061 ggaactatca gcattggcta taaaacaagc tcaaggtgat atattagaag cctctttcta
    15121 tgtaagagct ttaaggtcaa caatgcctag aattacatat tcagaaccca taaatacaga
    15181 agaaatgaga ataaaaagaa gaatatcagc tacttttaaa gatataccag gaggtcagta
    15241 tcttggggca actagagact atgaaaatag aatattgaat gtagaattat tagaagaaga
    15301 tgaaaaaaag aatagacatt ttagagatag ttttataaat gaattagaaa cagtagatga
    15361 aatccctgaa tttacaaaaa tatctaatat atttagaaaa gaaaatttat tacaagaaga
    15421 agtttgtgaa aacaaattgg aagaagttat tgatgatatt acaagaaata gtttaagatt
    15481 tccagtttct aggtcagcaa agttacaggc attaactaga ggtgaaagtg gagtagtgtc
    15541 aggttttgct tatgctattg taagaggttt tggtgatgaa catccatata taagtgaact
    15601 tagaactggt aatgtattta taaaagtaaa acatcccatc tatgaagatg aagaaataat
    15661 aataggggat atgctggtta ctgaatgtga aatagtttca aaagcatcac aaaataagac
    15721 tgaaaattct aaaactaatt cggaagataa aaataagatg tctttaggat atggtctttg
    15781 tatggggaat aatgagaata aggctatatc tatggccata ctagacaaat ctttggagcc
    15841 aaatagtgaa aaactagcac aagatgaaga atttgtattg cttcatatag atggaataga
    15901 ttcattagga tttatatctc actttaagct tcctcactat gtagatttta aagcggatgt
    15961 agaaagaata aaatagtttg aggaggtaag tttaggtgat atataactat ggttttttag
    16021 acgaaaacac aaaaaaagaa ataagaagaa agatattaaa agcaatatca atacctggtt
    16081 atcaagttcc ctttggttca agagagttgc ctatagctaa gggatggggt actggaggtt
    16141 tacaattaac actatcatta attggtaaaa atgatgtagt aaaagtaatt gaccaaggaa
    16201 gtgatgattc tacaaatgct tgtaatataa ggagctttat tgcaagtgta agtaatgtag
    16261 aaaccacaaa agatacatta gaagctacat tgattcaaac gagacataga ataccagaag
    16321 aaaaacttaa atctaatcaa atactaatat ttcaagtacc aataccagaa acccttagaa
    16381 tagtagaacc tagtgaagta gaaacaagaa gaatgcattc agaagaagat tatagtagga
    16441 tgtgggtata tctttatgaa gatatagtta gatttaatga tatatctata gcagttgaat
    16501 atccatgtaa agtaaatgat agatatttaa tgaatccatc acctatacct agatttgata
    16561 taaaaaaatt aaatatgtca gacaatttat tcttgtttgg tgcaggtaga gaaaaaagaa
    16621 tttatgctat tcctccatat acaaaggtag aacctttaga gtttgaggat tataagtttg
    16681 aagaggaaaa gtttgaagga aaatactgta gtttatgtaa cagtacaaat acatttttag
    16741 atgaagtata tgacagtgac actaatgaaa agtactatag ttgctcagat acaagttatt
    16801 gtgaaaaagt tagattaaaa aataacagta tagatgtgac aataggaggt acttggaatg
    16861 agtaaaataa atgactctaa aagattagaa aatatagaca agcaagtatt aataggaaga
    16921 aatatcaatc ttatttatgg agatgggtgt gaaaagtgtt ttgaaagcac aggatatgaa
    16981 agcaataata tatgtaagta ttgtggttct atagttgcat gtaataatgt aaatttagaa
    17041 ctttatgaag gagaagtcct tggaattgta ggtgaatctg gttcaggaaa aagcacttta
    17101 ttaaaaatac tgtttttcca agaacatgca aatagtggag aagtatatat atcccattac
    17161 aataaagaca caaatatact agagctttca gaccaaaaaa agagatacat aaagaatcat
    17221 tttatgggta ttgtgtatca aaatccccac cttggtttaa atttagactt tagtagtggt
    17281 ggtaatatag cagaaaaatt attgatggca aatttatata atgttgaaaa aataagagat
    17341 agaggcaaag aacttttaat aaaaactaat atacctgtag aaagaataga ccataaacca
    17401 aaatacttta gtgggggaat gcaacaacga gttcaaatag caaaagctct ttcaaataac
    17461 cctccaatat tgctattaga tgaggttaca acaggtttag atgtttctgt gcaagcggaa
    17521 gtattggatt taataagaga aatccaaaga gaacttaaga tttctatgat agttgtatcc
    17581 catgactttg atgttataaa gatgcttgct gataggacaa ttgtaatgaa aaatggaagt
    17641 gtaattgagt ctggtcttac agaccaaata atggaggacc cacaacaccc atatactcag
    17701 caacttataa attcattgct ataaatatcg tttgtaaata agcaaaatgg gggtttttaa
    17761 taaaatgaaa gaaactatac ttgaagtaaa taattttagt aaagactttg agttacatgc
    17821 attgaacaag actataacgg catgtagtaa tataagtttt gaagtttcaa aaggtgagtt
    17881 tttaggaata ataggtaaat ctggagcagg taagtctacc atattaaaaa gtatctataa
    17941 aacatatata ccaacaactg gagaaataat ttttaattca gaaatatatg gtaatgtaga
    18001 cctggctaaa attggagacc gagaaatgat aaatcttaga aagaaagaaa taggatatgt
    18061 atcacagttt ttaaagacac ttccacgaat aactgcaatt gaactggtag tacattcttt
    18121 aattgagagt gggtttgaaa aagattgttc gtatgatatg gcaaaagata tacttaacca
    18181 atttgaaata aaggaaaatt tatgggatgc gtatccaaat aatttttctg gtggagaaaa
    18241 attaagatta aatttagctc aagctatggt taaaaagcct agacttttgt tacttgatga
    18301 accaactgca tcacttgata atcaatctaa aatatatgta aaagaaaaaa tgttggagct
    18361 taaaagtcaa ggaactacaa tgataggaat ttttcatgat atagagttta tggaaactgt
    18421 tatagataag acctttacta tgacaaaagg gactataagt gaaagtgggg tagcctagat
    18481 gataaaacta attcataatg caaatattgt attagaagat atgattttag aaaatggtca
    18541 tttaatcata gagggagata caataaaaaa agtatcaaat gataagattg attacgcatt
    18601 tgactttaat gagatagatg aaataataga tgcaaaaaac ttatatgtaa tacctggtat
    18661 tatagatatt cacagtgatg ccattgaaaa ggaaatagag ccgagaccaa gtacattatt
    18721 accatttaat atggcatttt atgaactaga taaaaaacta cctgcaaatg gaataactac
    18781 agtttatcat tctatatctt taggggatgg agtaggagtt agaagtattg ataactcttt
    18841 aaagatgatt aaaaatattg attcatataa aaatatagat agtaagagca taaatcataa
    18901 agttcattta agatatgaag tgttgtatta tgaaggttta gaaaaggttt tagaactatt
    18961 agatgaaaat aaaatagact acttatcaat aatggaccat tctccaggac aaggtcagta
    19021 tacaaatcca acattttata aagagtatgc tactaaagtg tggggagtta cagaaaatta
    19081 tgtagataca tggttagatg atttagtaaa tctgcatgat aatttagatt ggaataaaat
    19141 agctaatatt ataggtatag ccaaaactaa aaatataaat gttgcatcac atgatgatga
    19201 tacattagaa aaaatggatt tcataaaaaa tataggcata aatgtatctg aatttcctat
    19261 aactcttgaa gttgcaaaac attcaaagaa attgggtgtt ctaacttgtt taggtgcacc
    19321 gaatattgta agaggtaaat ctcataataa caatttaaaa gcaatggatg ctatattgga
    19381 agattgttgt gacattgtgt gttcggatta tcttccatca gctatgataa agtctatgtg
    19441 tatagttgca gaaagaataa ataatttaaa taaagcagtc agtttattta cctcaaatcc
    19501 tgctaaagca gttggtatat atgatgaaag aggtagtata aaagaaaata aaaaagcaga
    19561 tttagtttta gtagatattg atagtgaata tccaaaggtt gtaaatacta ttgtaaatgg
    19621 aaaaacagtt tataaaaggg aggtataaag attgctaaca gagttacatt gtcatacaag
    19681 tatatcagat aataatttta ctactgaaga aataataaaa aaagcagcag aaaagaatat
    19741 aaatatctta gcaataacaa atcatgacac attatctgga ttggatgaag ctcttgtgct
    19801 tggagagcat tatggaataa caataatacc aggtatagaa atttcagcct atgattataa
    19861 aaatagaaaa agagttcata ttcttggata taacatagat ttaaacagtc aagaaataaa
    19921 aaatttgtgc aatccaatgg tatgtgacag acataaagca tctgttaaga tggtaaataa
    19981 aattatagat ttaggataca aaatatctct ggaagatgta aagaaatatt catcaaagac
    20041 tggaatattt aaacaacata taatgaaagc tcttatagat aaaggatata cagataatat
    20101 atattcaaat ctatataaag aattgtttca tagaggaaac ggcaaggtat atgtatcttt
    20161 aaaatatgtg gattacagag atgcaataaa agctataaaa aattctggtg gaatttgtgt
    20221 gttagctcac ccgggtcaaa tggataattt tagcgctatt gaagagatgg taaaagtagg
    20281 attagatgga atagaagtat atcatccatc tcacaacaaa gaactagaaa aagagtcgct
    20341 ttcttatgct aagaagtata atctagtggt cacaggaggt tcagattacc acggatttta
    20401 ttctcaacat aattatgaac ttggaagcaa gagcttaaat aaagaagatt tatttaagtt
    20461 taggttagct ttaggagggg tattataaat gtctttttta caagtaaaaa atgtaggtaa
    20521 aagttatgga caagttaagg tgttaaaaga catatctatt gatattgaaa aaggagagtt
    20581 tatttgttta ctaggtccaa gtggttgtgg aaagagtaca ctacttagaa taattgcagg
    20641 gcttgaggat aaacatggtg gaaaaataat aataaatgat aaggatatga ctaattcacc
    20701 acctgaaagt agaaattttg gtatagtttt tcaatcatat gcattatttc caaatatgaa
    20761 tgtttacaaa aacatagcct ttggactaga aaataaaaac ataagtaaat ctaatattga
    20821 taaaaaagtt aaagaagttc tagaagttgt agaattaagt ggatatgaga aaaaatatcc
    20881 atcacaatta tcaggtggac aacaacaaag ggttgcatta gctcgtgcga ttgctttaga
    20941 gccagacttt ttacttcttg atgaaccttt atctgcatta gatgcaaaag taagacttaa
    21001 acttagggag cagattagaa gtttacatag aaaactaggc attacaacta taatggtaac
    21061 gcatgaccaa gaagaagctc tttgtttagc tgataagatg gttgttatga atagaggaga
    21121 aataatacaa gttggaacgc caaaggaggt atataaaaat ccagaaacac cttttgtagc
    21181 tgattttata ggaacaataa attttataga tgatggtatt aataagatag ctattagacc
    21241 agaagatata aaagtagagt ctaatagaga ttctaaagat aaggatataa aagtgggaga
    21301 aattttagat atcgaattta gaggatttaa ctatagaatt acagttgagt atcgttctaa
    21361 gcaaatgaaa ttagatgtag tttccaaagt tgcagaacaa atgaaactgt gcataggttc
    21421 taaaataaac tttaagatac ctaaagaagg aattgtacaa tataaatcag agggatgtgc
    21481 ttaatagcta ggggtgaata aatgataaca tcaaaaaata aaagaagaat aagtgatagc
    21541 acaatacaaa aatatttctt gattttttcg gtaattgtac taatagtatt tatattattt
    21601 ccattagtat cattattaaa aaatgcattt atggatacaa gtggaaattt tataggaatt
    21661 tcaaacttta gtaaatatgt tgaaaatcca agtcttatag catcatttaa aaattcaatt
    21721 tttgtatcta cagtctcatc tttaatatca ctatgtttag catttatata ttcatacgca
    21781 ataacaagaa caaacataaa gtttaaagat ttttttaaaa ctatgggaat gtttccactt
    21841 tttgcaccaa ctatgttata tggtatttca cttatatacc tttttggaaa taagggaatc
    21901 tttacaacca tgggtctgga agtaccacta tatggtccat taggaataat tatttctcag
    21961 attctattta catttccaca agctttttta atattatctg tagcactttc gatggctgat
    22021 tatagacttt atgaagcagc agatagcttg ggtgctagtg aatttaagaa attttgcaaa
    22081 ataacaattc ctggtataaa gtactcatta cttagttcat tctttgtatc ctttatactt
    22141 gcatttacag attttggagc agctaaggta gtcggaggaa actacaatgt actggctact
    22201 gacatatata aacaagtagt tggacaattt aacataccaa tgggagctac tgtttctatg
    22261 gtaatgttaa ttcctgtact aatagcattt acattagata agatggcaag taagaaacaa
    22321 ggtatgacca taactgcaaa gtctatgcca tataagatta aggaaaataa gtttagagat
    22381 agagtatttt taatagtatg tagttttata acattgctaa tttttatttt aatattcgtt
    22441 tcagttatag gttcagttat aaagttatgg ccatataatt taagctttac aatggaacac
    22501 tatacattta aaggtatttt gggaagtgga ataaaaacat acttaagcag tttgaaaata
    22561 tcaactttaa cagcaatatt tggaactata tttgtatttt ttagtgctta tatgatagaa
    22621 aaggtggata agtttcctaa attaagacaa acagcttacc ttttatcaat gataccaatg
    22681 gccttacctg gcttagtttt aggtatatca tatataactt tttttaactc agcaagtaat
    22741 ccattaaatt ttttatatgg aagtacagca atattagtta tagtaaatgt agttcatttt
    22801 tattcagttt gttttataac ctcaaattca tctttaaaaa tgttggataa agagtatgaa
    22861 ttagttgcaa aatccataaa tattccattc tataaagtat tttttaatat aacagttcca
    22921 atgtctataa catcaatact tgaaatagta gtatattatt ttgtaaattc aatggttact
    22981 gtttcagcat taatattttt atatacacct caaactcaga ctgcatcaat atcaatacta
    23041 aagttagatg agataggata tataggaaca tcagctgcta tggcagtatt agtgctttta
    23101 acaaatataa tagtaagact tttgtacgaa tttgtaacaa agaaattaaa aaataacaca
    23161 caaaaatggc agcaaaaaga tgttgcatag gggaggtaaa aatgaaattt aagaagctag
    23221 tttctttagg agtattatca acacttttat taagtgtaat aacaggatgt agtactgatt
    23281 catcaggttc agattcaaag tctgatagta agacaaaagg ggatttaaca gtttacacag
    23341 caattgaaga agatagtata gagccatatt tagctacatt taaagagaaa tatccagata
    23401 ttaaattaaa tattgttagg gcatcaacag gagatataac agcaagatta ttagcagaaa
    23461 aggataatcc tcaagcagat gttgtatggg gagttgcagc cacaagctta ttggttgcag
    23521 atgaccaggg gatgttagaa ccatatgctc caaaaggttc tgaagaaata gagtctgcat
    23581 ttaaagatga taaagaagtt ccttcttggg ttgggataga tgcttggatg acaggtataa
    23641 cagtaaacac taaagaatta agtgataaga acatcccagt tcctagttct tacgaagatt
    23701 taataaagcc agaatataaa ggtcttatat ctatgcctaa tccatcttct tctggtacag
    23761 ggtacttaac agtatcagcc cttatacaaa ttatgggtga agaaaaagca tggcagtata
    23821 tggataaatt gcatgagaat attggtgtat acactcaatc tggttcagct ccagctacat
    23881 cagcagcttc aggagaatat cctattggta tatcttttgg atatagaggt ataaagttaa
    23941 aagaggaagg ctatccagta gaagtagtat ttccaaaaga aggttctgga tgggatatag
    24001 aagcaaatgc tcttgtgaaa aaagataata taaaagaagc atcaaaagta tttttagatt
    24061 gggctataag taaagatgta atgaacgaat actctaagaa ctatgcagtt actactattt
    24121 ctacaggaaa tccaatacca gaaggattcc ctaaaaagcc attagagcaa atgatagata
    24181 atgatttaaa atcagcagca aaaaatagag aagatatact aaataaatgg atatcaaaat
    24241 atgatggtaa gacagaaaaa gagagttaag taaaactata caaatggagt aaaaagaaag
    24301 aattttttta agtagatttt attataataa tataagttga gaataatata ggtcaagaaa
    24361 agtgaatatt ctataaaaat gtatagagta agtataccat tcagtttgaa tggtatattt
    24421 tttattttta gagattaatt tagaaataga tatactacag tttaaaatag tatattttaa
    24481 tttcattatt aaagtataga tattatatat aaagtaaata aattattgag cgattattaa
    24541 taagatatgt ataaatttta atttgggaac ttgtgttata tatcatgaaa aaagagaaaa
    24601 aataaaaggt aaattgtttc ttgataactt gaaattggaa gtgagaatat ttaactagag
    24661 aagaattatt taagtttaag tcagctttag gaggaggaat tataaatgtc ttttttacaa
    24721 gtaaaaaatg taggtaaaag ttatggacaa gttaaggtgc taaaagacat atctattgat
    24781 attgaaaaag gggagtttat ttgcttatta ggtccaagtg gttgtggtaa aagtacattg
    24841 cttagaataa ttgcaggact tgaggataaa catgatggaa aaataataat aaatgataag
    24901 gatatgacta actcaccacc tgaaagtaga aactttggta ttgttttcca atcatatgca
    24961 ctatttccaa atatgaatgt atataaaaat atagcctttg gattagaaaa taaaaatata
    25021 agtaaatctg atatagataa gaaggttaga gatattttag aagttgtaga attaagtgga
    25081 tatgataaaa aatatccatc acaattatca ggtggacaac aacaaagggt tgcactagct
    25141 cgtgcgattg ctttagagcc agactttttg cttcttgatg aacctttatc tgcattagat
    25201 gcaaaagtaa gacttaaact tagggaacag attaaaagtt tacatagaaa actaggcatc
    25261 acaactataa tggtaacaca tgaccaagag gaagctcttt gtttagctga taaaatggtt
    25321 gttatgaata atggagaggt aatacagatt ggaactccta aagaagtcta taaaagtcca
    25381 aaaacacctt ttgtagctga ttttatagga acaataaatt ttatagatga tgatgtgaat
    25441 atgatagcaa ttagaccaga agatataaag gtagaattta atagagactt taaagaaatt
    25501 gatgtaaaag taggagagat tttggatata gaatttagag gattcaacta tagaattaca
    25561 gttgaatatt gttctaagca aataaagttg gacgtagttt caaaggtagt ggaacaaatg
    25621 aaactatgtg taggttctaa aataaacttc aagataccta aagaaagaac catacaatat
    25681 aaatcagagg gatgtgctta atagctagag gtggataaat gataacaata aaaaataaaa
    25741 gaagaataag tgatagtaag atacaaaaat gttttttagt ttttttagtg attgcattag
    25801 tagtatttat attatttcca ttaatatcac tattaaaaaa tgcatttatg gatacaagtg
    25861 gaagttttgt aggaatttca aactttagta aatatattga aaatcccact cttatagcat
    25921 catttaaaaa ctcaattttt gtatctacaa tttcatcctt aatatcatta tgtttagcgt
    25981 ttatatattc atatgcaata acaagaacga atataaggtt taaaaacttt tttaaaacta
    26041 tgggcatatt tccgcttttc gcaccagcta tgctatatgg tatttcactt atataccttt
    26101 ttggaaacaa gggaatcttt acaattatag gcatagaagt accactatat ggtccattag
    26161 gaataattat ttgtcaaata ctgtttacat ttccacaggc ctttttaata ttatctgtag
    26221 cactttcgat ggctgattat agactttatg aagcagcaga tagcttaggg gctagtgaat
    26281 ttaagaagtt cttcaaaata acaattcctg gtataaagta ttcattagtt agttcgttct
    26341 ttgtatcttt tatacttgca tttacagatt ttggagcagc aaagatagtt ggaggaaact
    26401 acaatgtatt ggctactgac atatataaac aagtggtagg tcaatttaac ataccaatgg
    26461 gagctactgt ctctatggta atgttaattc ctgtactaat agcatttaca gtagataaga
    26521 tagcaagtaa aaagcaaggg atgactataa ctgcaaagtc tatgccatat aagattaagg
    26581 aaaataagtt tagagataga gtatttttaa tagcatgtag ttttataact ttattaatct
    26641 ttattttgat atttgtttca gttataggct cagttataaa attatggcca tatgatttaa
    26701 gctttacaat ggaacactat acgtttaaag gtatatcagg aaatggaatc aaaacatatt
    26761 taagcagttt aaaaatatca attttaacag caatatttgg aactatattt gtatttttta
    26821 gtgcttatat gatagaaaaa gtggataagt ttcctagact gagacaaata tcttattttt
    26881 tatcaatgat accaatggca ttacctggtt tggctttagg tatatcgtat ataacttttt
    26941 tcaattcagc aagtaatcca ttaaattttt tatatggaag tacaacaata atggttatag
    27001 ccaatatagt tcatttttat tcagtttgct ttataacttc aaattcatct ttaaaaatgt
    27061 tggatagaga gtatgaatta gttgcaaaat ctataaatat tccattttat aaggtgtttt
    27121 tttatgtaac acttccaatg tccataacat caatacttga agtggctgta tattacttcg
    27181 taaattcaat ggttactgtt tcagcattaa tatttttata tatacctcaa actcaaactg
    27241 catcaatatc gatactaaag ttagaagaga tagggtatat agggccatca gctgctatgg
    27301 cagtattagt gtttttaaca aatataatag taaaactttt gtatgaattg acaacaaaga
    27361 aattaaaaac taagacacaa aaatggcaac aaaaagaagt tgcatagagg aggtaaaaat
    27421 gaaatttagg aaattagtct ctttaggaat attatcaaca cttttattga gtgtaataac
    27481 tggatgtaat aatgcttcat caggttcaaa tttaaagtct aataataaga taaaaggaga
    27541 gttaacagtt tatacagcaa ttgaagaaga tagtatagat acatatttaa ctacatttaa
    27601 agagaaatat ccagatatta aattgaatgt acttagatta tcagtaggag atataacagc
    27661 aagattatta gcagaaaaag ataatcctaa agcagatgtg ttatgggggg ttgcagctac
    27721 aagtttgata attttagatg acaaagaaat gctagagcca tacgctccga aaggctttga
    27781 taaggtaaat cctgtattta aagatgataa gaaagttcct tcttgggttg gaatagatgc
    27841 ttggatgact ggtataacag taaatactaa agaattaagt gataagaaca taccagttcc
    27901 tagttcttat gaagatttaa taaagccaga atataaaggt cttatatcta tgcctaatcc
    27961 agcttcttct ggaacaggat atttaacagt atcagaactt atacaaatta tgggtgaaga
    28021 aaaagcatgg cagtatatgg ataaattgca taaaaatatt ggtgtataca ctcagtctgg
    28081 ttcagcgcca gctatattag cagcttcagg agaatatccc attggtatat cttttggaaa
    28141 tagaggtata aagttaaaag gtgaaggtta tccagtagaa gtagtatttc caaaagaagg
    28201 ttctggatgg gagatagaat caaatgcact tgtgaaaaaa gataatataa aagaagcatc
    28261 aaaagtattt ttagattggg ctataagtaa agatgcaatg aatgagtatt ctaagaattt
    28321 tgcagttact acaattgaca cgggaaatcc ggtgccagaa ggatttccaa agaatccatt
    28381 agaacagatg atagataatg atttaaaatc agcagcaaga aatagagagg ctatactaaa
    28441 taaatggata gaaaaatatg atggaaagac agaaaaagag agctaagcct tgcaataaaa
    28501 tttagtacaa aaagcgccta gaatataagt tttatatcta ggctcttttg atatatttat
    28561 ttaaaatgca tatttctata taaaaataaa tagtttagta ccttgattaa attaaataaa
    28621 aaccttaaaa taaagagatg taaagaaaaa ctaaaaacga ataaaaggtg aatttatatg
    28681 ataaaagaaa taatagtagt agagggtaga gatgacgtta cagcagttaa gagagcaata
    28741 gatgcagaac ttataactac aggtggattt ggatttccaa aaggtgtaat ggagcgtata
    28801 aaagctgcta atgaaagacg tggtgttata atatttacag acccagattt tgcaggtgaa
    28861 aaaataagaa aaaaaatagc atcagaagtt ccaggatgta aacatgcatt tctaccgaga
    28921 gaggaagcta aaaaggatgg agatataggt attgagaatg ctactcctca aagtataata
    28981 gcagctctga ataaagttag aactgaaaat acagaaaaaa gagatgaatt taagcaagtt
    29041 gacttaatta gaaatggtct tataggtaat gaagaagcat cacttagaag agatgcactt
    29101 ggaaaaatac ttggaattgg atatggaaat gcaaaacaat ttttaaatag attgaataat
    29161 tatggagttg aaagagaaga atttatagat gcattaaaac aaatctaaac gtaatgttta
    29221 atgtatgaaa aatatgtata taaaataaat tgtggaatta cggttaattt aagatgaatt
    29281 atttataata tacaccttat tttaaatcaa tgtaaataca tataaataag tataattaat
    29341 aaaattaaat atcaaaataa gttaaaaagg agtaaataat ggatagacta tcttcacata
    29401 atgcaacaaa ggaagtagta caaaaatata attttaaatt ttcaaagtct ttaggtcaaa
    29461 atttcttgat agatagtaat ataattgata aaatcttatc tggagctaga atcacaagag
    29521 gagataatat catagaagta ggacctggta taggaactct tactcgtgag atgggtaaaa
    29581 tagcagaaaa agtagtggct atagaaatcg atagaaattt aattcctata ttgaaagata
    29641 ccttgtcaga tttagataat acagaggttg taaatcaaga tatactaaaa gtagacatac
    29701 aggaattagt aaaagataaa ttaaatggtg ggccagttaa gcttgtagca aatcttccat
    29761 attatataac tactccaata gttatgaaat ttttagagga agacatacct gtaacagaca
    29821 tagtagtcat ggttcaaaaa gaagttgcag atagaatgaa tgctattccg ggtactaaag
    29881 attatggggc attatctata gctgttcaat actattgtga tacagagatt gtggcaaaag
    29941 ctccaagaca tatgtttata ccacaaccaa atgtagattc cacagttata ggtctacatg
    30001 taagagataa aagaaaatat gatgttcata atgaagacat attttttaaa acagtaaaag
    30061 catcctttgg acaaagaaga aaaactcttc ttaattcgtt gggaggtctt ggttttctta
    30121 ataaagatga aataagagaa gtattaaaag aagctaatat agacgaaaaa agaaggggtg
    30181 aaactcttag tatagaagag ttttcagttc tttcaaatat aataaataca aaagtatctt
    30241 ctaaatagaa ggtacttttt ttaattttgt taacatatat tgtttagaga aactgtgtta
    30301 aggggggatt gcagtgggtt ctaaaagaaa gtttaaaaga gactatataa tactagaagc
    30361 taaagacata aactttagat acaaagaacg agtactgcca aaagcttttg caaaagttga
    30421 agtaaatgat gaaaaagcaa ttattgcatt atatgtagaa aatctaaaat atgttaaaga
    30481 tgggtataaa gcagtagcaa taaaagatga ccatggatta atagacttag gaaatataat
    30541 tttaaatgaa caaggaagag gtgaatttgt tttagattta gaagattatg atgatgagat
    30601 aaaaggtatt gcattattgt atgaaagaaa tataccttta attggattta aaggaaataa
    30661 gcttgaaaat tatgaggaca tattatttca agaggtagag gaagaagaat atgaagaata
    30721 tgaagagttg gaagaagaag acgaagagat agaggataat gaggaaagtg atagagacga
    30781 aggtagtgaa gaagaatata ttatagaaga atatgatgaa gatgagtatg aagactattg
    30841 ggaagatgat gaagatattg acgaaggaga gttaaaagca agaacggaag tagaagattc
    30901 tggtgatgag gaaatagaag agttcaataa ttataaggaa atagaaaatt ataatagggt
    30961 taaagtacag gaagaatata tagacataga atatgatgag gaagaagagg aagaagaaga
    31021 agtttttgaa gtaaatagag aagaagatag gtttgtttcc tcaaaaccta ctaaatcaaa
    31081 gaaagttcaa aaagatcaga ataatattga aaaaataaaa agagctaatg gagtaagtca
    31141 aggagagagt ggaaataaac aaaccagtac attacttatg ccaagacaaa taaaaaaagg
    31201 tttgaaatta tttaaagaag taaaaccttt tgtaacagat tatatagata agacaagatg
    31261 gtggaaaata gagataaatc ctacaacatt gtgtggatat acaatgcctt atttaggata
    31321 tttaaacgtg ttgaattaca ccatgtatag tgatgcagtt ttacattcat ataaatacag
    31381 acactattta tttggagtcc agtatgatga atataataag agaaaacatt atatttatgc
    31441 tatcccagga aatagaaatg aacagccaga caatggaagc acaggatttt taagatatca
    31501 agcttgtgat aatagaacaa atagtttagg atattggcta tgttttatag attctagaca
    31561 aagaaatata gttaggtaaa aataataaaa atgaaaaaat ttagactcaa ttcttatttt
    31621 actgaaaaaa ttaatgaaat gtagtacaaa actttaaaaa ctattgataa tatttaaata
    31681 ttacactaca atatatcttg aaatacctat tatattatgg aggaaaatta tgataaacga
    31741 gcaaagaatt ttaaatgagt ttcttgaatt agtacagata gatagtttat ctttaaaaga
    31801 ggggaatgtt gctaaagtat tagttaaaaa attagaagaa ataggttgtt cagtagtaat
    31861 agacaatgct ggtgaaaaag caaatggaga aactggtaat ataatagcta cattaaaagg
    31921 aaataaagaa ggaaagaaaa tattatttag ttcacatatg gatacagtaa ctccaggtat
    31981 aggggtaaaa cctatagtgg atgaagcaaa tggaataata aaaagtgatg gtactacaat
    32041 attaggttct gatgataaag caggtatagc agctatatta gaaggcttaa gatatataaa
    32101 tgaaaataat atagaacata ctgatataca agttgtattc tctatatgtg aggaatgtgg
    32161 attagttgga gctaaaaatt tagactatgg aaaaatagat tctgaatatg catttatatt
    32221 agatagtggt ggttctccag gtgaaataat agtaaaagct cctgcacaag atgtaataaa
    32281 tgttaagata ttaggaaaga ctgctcatgc aggtcttgaa cctgaagctg gaataagtgc
    32341 tataatggta gctgccagag caatagaaaa tatgaattta cttagaatag acgaagaaac
    32401 aactgctaac ataggaatta taaacggtgg aacagctaca aatatagtaa caggagaagt
    32461 taatataatt gcagaagcca gaagtctaaa agaaaataaa ttagatgttc aaactaaaca
    32521 catggtagag acttttgaaa aagctgcaaa agattttgga gctcaaattg agatagatgt
    32581 caatagagca tatacaccaa tagatgttag tgaggattct gaaataataa aacttgcaaa
    32641 gaaggctttt tcaaacttag gtatagaagg tcatactgaa tctacaggag gaggtagtga
    32701 tacaaatata ttaagtaaga atggtattga agctataact ttaggaattg gtatgaaaaa
    32761 tgctcataca ctaagtgaac atatagctat aaaagactta tatgattctg ctaaaatggt
    32821 agtggagata ataaaggaag cataaattta aataatagtg tataatatat atatcgccta
    32881 gcttaagcta ggtgattttt cattttatag aagattgata atctctattg aaagtaaaga
    32941 gtatacattt gcatataaga gagtgtttaa tttatgttca aatgtaggtt cttaataata
    33001 tttagattgt ttcataaggg aggaataaat atggaaacaa ggtatgaaga agcaaataaa
    33061 ataacaatac aatcaatact ttggaatgta gtattaacaa taattaaggt tatagctggt
    33121 gttattggta attctagcgc tatgattgcg gatggattac attcagcatc agatattata
    33181 agttctatag gagtactaat aggcaattat gtatcttcta gacctggaga tagagagcat
    33241 aattatggtc atgagaaagc agagacatta gtatcatttg tgttatcaat attgcttatt
    33301 ttcgtttcta taacaatagg tatagaggca attaaatctt tatttaactt agatgcatta
    33361 agtgttccat caatattacc attagtagta tcagttattt caatcctgat aaaagagtat
    33421 caatatagaa taacaataaa agttgctaaa aagataaatt caccagccct aaaagctgat
    33481 gcttggcatc ataggtcaga tgctttatct tcagtagctg cttttatagg tataggtggt
    33541 tctattttag ggtttaaacc attagaccca attgcgtcag ttgtagtggc tatatttgta
    33601 gctaaagtag gaattagtat acttataagt tctgttaatg aattgatgga tgtttcagtt
    33661 gatgaagaag agataaaaga attaaaattt attgtagcag atacagaagg tgttaaaaat
    33721 cttggtgata taaagactag aaaacatgga gctatggcat atgtagattt gactatatgt
    33781 gtggatgaaa atttgacagt taagcaaggt catgatattg ctaccaagct tgaaaaacat
    33841 ataataaaac atatggaatt tgtaaaaggc ataacagttc acgttgaacc atgtactaat
    33901 tgccaaggaa ataagtgtaa taattaatta aaacttaaaa aaaagtgtaa aaagttatat
    33961 aattgtttta tgattataaa ctctaggggt ggttaaatga gcaagaaaag aaaactaaag
    34021 aaaaaagctg caatattaat aggagtagtt gttttcttta taatatactt tatatccttt
    34081 agaataggaa taaatatgga aaaggataaa agtgaagtgc caaagaaggt agaaaaagaa
    34141 gaagaagata ataggtcttt aaggactcaa ataaaagaga agaagaaggt ttatatatca
    34201 gataaaaata tagaaaacat aaaaattgaa gaagatatgt gggatgaaat aaagttattt
    34261 ttctcagatt ttaagaaagt aagaaatact acttcttctt acgaagcagt ttatgaaggt
    34321 tattctgatg atggagttaa attttctact gaccttaact tttttagagt atatactgta
    34381 aataaagaag aatattataa agtaccagtt agttctaagg atgcttttaa gaaactttta
    34441 gatgagagca tatatacttc gtttgacctt ttaagtcatt ataaagattg gaaagaggtt
    34501 actataactc atggaaaaga aattaaaaaa gttcatagat ggaaatttga tgatttagca
    34561 cataagatga tttcaaagag ggttgtagga aaagttcaac ctgagaaaag taaggaaaga
    34621 agtgactata attttactat aaatataaaa ggtgataatt ttgatgtaaa agttgataca
    34681 atgggaaaag attatgtaaa agttacttct aagaaaaatg tatcttacta tgaggttcat
    34741 acaagtttat ttgattacct taaaaatgag atatttgaaa ttggaaagaa ataagacttt
    34801 aagaaggcta tcaaattaga tatttgatag cctaaattat tttatatatt atttttcaac
    34861 caacaagtct gcaaccttat aaattggacc agcaccagca gttattacta aatcattatc
    34921 cttaacattt tcacgtaagt attttactat atcttcaaat tcttttatat agatggcatc
    34981 tacattgttt tgatataatt tctcaaccaa gtccttagaa tgtatatctc ctgggtcttt
    35041 ttccctagca gcatatatat ctgttatgat aactttatca gcagcataga atgcctctga
    35101 aaattcacct aaaagagatt ttgttctagt ataagtatgt ggctggaaga tacaccataa
    35161 agttgatttt tttaattttt tggcagcagc taaagttgct tttaactcag ttggatgatg
    35221 tgcataatca tctactacta aagcattctt ataataccct ttagtttcaa atcttcttcc
    35281 gacaccttta taaattttta tattttttct tatagtctct aagtcaatac cagaaacaag
    35341 agctgccatt atggcagaag aagcattgta tatgttatga agaccatata cagaaagttc
    35401 aaattctcct aaatctcttc cttcatattc tattctaaat attccatgac cactattgtc
    35461 aaagtgaata tcttttatta cagcatcatt gtcagaatct ctgccgtatt ttataatagt
    35521 agctttaaca tcatacaata tgtcatcaat attttcatca tcgccattta ttatgaaata
    35581 gccttctggg ggtaataatt ttccaaattt gttaaaagaa gctttgattt catctattcc
    35641 agagaaataa tcaagatggt cttcttcaac atttaaaact atagatatct ttgggttaaa
    35701 attaaggaaa ctatctacat attcacatgc ttcagttata aagtggttgg aattacctat
    35761 cttaacatta ccacctatca tacttaagtt accaccaact agtatagttg ggtctaagtc
    35821 tgcatattca aagattgtag ataacataga tgttgtagaa gtttttccat gtgttccaga
    35881 aactgctata gaatttttat attccctcat gatttggcct aaaaaagtcg ctctgttcat
    35941 taccaattta tttttttctt tagcagccac aagttcttca ttgtctggat gaactgctgc
    36001 tgtataaaca accatattta catcatctga tatattatct tttttctgac caatataaat
    36061 agttgcccct tggtccctaa gtttgtctaa taggtatgat tcgtttgaat ccgaacctga
    36121 aacttgataa cctttattga tacatatttc agctaatgca ctcatgctga taccgccaat
    36181 tcctataaag tgtatattca taataaaacc acctttcttt ttaattaagt cctacaatat
    36241 gaactatttc tgtggtataa taatataatg ttcaatattt tataattaat atgcatataa
    36301 tattatatgt attttatttt tgaatataat aaaacataag taatattata ccacaataag
    36361 aattgttatg cattagttag tttaacgtta tataaaggta cttgtaggag gaaataataa
    36421 tgaaatttaa aagaacagag agaattggag caatagttaa aatactgtct gataatccaa
    36481 ataaaatata tactttaagt tattttacaa atcaatttaa tgcagcaaaa tcaacaataa
    36541 gtgaagattt attagttgta aaaaatgtat ttgagaagct acatttaggt aaagttataa
    36601 ctatttcagg agcagcagga ggagtaaaat atatacctaa aacttctata gcagaaaatg
    36661 cagagttctt aatggaatta tgcgagagaa tatgtgacaa gtctagaata ctatctggtg
    36721 gttttttata cttgattgac ctaatttacg accctacaat agctgctaag ataggaaaga
    36781 tattcgcatc aaatattgag tatgtagatg cagattatgt tgtgacaatg gaaacaaaag
    36841 gtatacctat ggcacttatg actgcaaaag ctatgaattt acctctagtt ataataagaa
    36901 aagatataaa ggtatcagaa ggtcctacac ttagcatgac atatgtgagt ggaaacagtt
    36961 ctaaagttga aagtatgagt ttgccaagaa aagctcttaa accagatagt aaagttataa
    37021 ttatagatga tttcatgagg ggtggaggta ctataaaagg aatggtagac cttatgaatg
    37081 aatttggtgc agaggttata ggtactggag tattcatatc tacaacgaat ccttcagaaa
    37141 aaatggtaaa agattatatt tcgttgattc aattggatgt taatggagat aaaatagtag
    37201 tagaaccaaa cttaaagact tttaaagatg aatatagaaa tgaagattta gacgaagaag
    37261 aagattcaga atttgaattt gagatagatg aagattaata aaaaaaatat ttagaaaaat
    37321 atgtaaaaat aaaaagagga tatccctagt tgttcataga attatttaaa aaacagttta
    37381 tattaattta ttccagcgat aataatttta atataaatta atttctgtca aaatcaaagg
    37441 gggatatttt ggtatgaaga taactgacgt aagagtaaga aaattaacag aagaaggtaa
    37501 gatgaaatgt atagtttcaa taactttcga taatttgttt gtagtgcatg atataaaagt
    37561 tatagaaggc cataatgggc tatttatagc aatgcctagc agaaaagtag gcgaaggaaa
    37621 tttcagagat atagctcatc caataaatgc agaaatgaga caagttttag aagatgcagt
    37681 tttacaagcg tatcatgaag cattagttca atgggaagta gctgctgaat aataataaat
    37741 atataaaatg gagagagccc gaacatttag gctcttttta aatgtagaat ttctattaaa
    37801 atatgtactt tttagtaaaa aagtgctata ttattagtga taatgtatat gttgtataca
    37861 aattgttaga taaatgtatt ataatgtata ttgattaaga gaataatacg aataaaatta
    37921 aattagattg aatggagtgt atcaatgaac tttaaagcta taatccttgc tgctggcaaa
    37981 ggaacaagaa tgaagtctaa atacccaaaa gttatacata aagtatgtgg aaaagaaatg
    38041 gttaaccata ttatagatgt ttcaaaaaaa tcaggggtaa aagatactgt cgtgatttta
    38101 ggacatgaag ctgatgtagt taaagaaaag cttgcagaag aaattataat agccatgcaa
    38161 acagaacaac ttgggacagg acatgctgta aagatggcta aagaatatat taatgatgaa
    38221 gatacaatag ttgtactttg tggagatact ccacttataa aagaagagac actaaagaga
    38281 ctatttgaat atcatataga aaataaatat catgctacag ttcttacaac aagagttgga
    38341 aatccaacag gttatggtag aataataaga gataagaagg gtgaccttct taaaatagtg
    38401 gaacaaaaag atgcaaattc agaagaaaag atgataagtg agataaactc tggaatttat
    38461 tgttttaatg gaaagagtct tagagaagca ctagatttgc taaataataa caattcacaa
    38521 ggtgaatatt atttaactga tactgctaaa ataatgagag ataaaggatt aaaagttggt
    38581 gcatttgcag gttcaactat tgaagaactt atgggcgtta actcaagagt agaattatca
    38641 aaggcagaag aaattatgag acgaagaata aatgaatctc atatggtaaa tggagtaact
    38701 ataatagaca ctaactctac ctatatagaa tctgatgtta tgataggcaa tgatactata
    38761 atatatccag gtgttatgtt acaaggaaaa acaaggatag gttcagattg tataattgga
    38821 atgaattcat ctataacaaa ttcagaaata ggtgatggta cagaaataaa aaattcaact
    38881 ataattgata gtaaggttgg agaaaattct actgttgggc catatgcata cttaagacca
    38941 aagagtgact taggaaataa tgtaaaaata ggcgattttg tagaagtaaa aaatgctatt
    39001 atagaagatg gctcaaaagc atctcacctt tcttatatag gagatgcaca tgtcggtaaa
    39061 aatgtaaata ttggatgtgg agtagtattt gtaaactatg atggtaaaaa taaatttaaa
    39121 tcaatagtaa aagacaatgc gtttataggt tcaaattcta atttagttgc accagtagtt
    39181 gtagaagaaa aaggatatat agcaacaggt tcaacaataa cacatgatgt cccagatggt
    39241 gctttggcaa tagcaagaga aagacaagtt atcaaagaag gatgggtaga aaaaaagaat
    39301 caaaaagacg accaaagtaa gtaattatgt agtttattat tttggctaaa aaatttagct
    39361 cgaaattatt ataaattata ttcattagta ttttaaaatt ttcaggaggg ttacataaat
    39421 gaatactagc ggaagcgaga ttaaaattat tgcaggtaat tcatcgaaag agttagcaca
    39481 aaaaatagct gactatatag gtgtatcagt actagattgt gaagtaggta catttagtga
    39541 tggtgaaata tgtgtaaaca tgaatgagac agtaagaggt tgtgatgtgt ttgtagtgca
    39601 atctactaac agcccagtaa atgataactt aatggagtta ttaatcttaa ttgatgcgtt
    39661 aaagagagca tcagcaggta gaataacagc agttattcct tactatggat atgcaagaca
    39721 agacagaaag gctaaggcaa gagatccaat cactgctaaa ttagttgcaa atttaataac
    39781 tgctgctgga gcagatagag tattaacaat ggatttacat gcagctcaaa tacaaggata
    39841 ttttgatata ccattagacc acttactagg tggaacaata ttagcaaatt attttaatga
    39901 aaagaaaata gaagatttag tagtagtatc tcctgactta ggaagtgtta ctagatcaag
    39961 aaaatttgct aatactttaa atggagaagt tccaatagct ataatagata aaagaagacc
    40021 gaaagctaat gtatgcgaag ttatgaactt aataggtgat gttaaaggta aaaatgttat
    40081 actattagac gatatgatag atacagcagg aacaatagtt aatgctgcaa atgcacttaa
    40141 agagtttgga gcaaaagatg tttatgcttg ttgtactcat ggtgtgttat caggtccagc
    40201 tattgaaaga attgctaatt cagaaataag tgagttaata gttcttgata ctatacaact
    40261 tcctgaagag aaaagaatag ataagataaa gataaaaaca gtagctcctt tatttggaga
    40321 tgctataaga atgatattct ctaatgaatc agtaagtaaa ttattctaat ttattgtatt
    40381 tatgagagtt gtttaaaagg atataaacct tttgagcaac tcttttttga ttttataatt
    40441 atggaatgtt atttttttct tgttagaaag gtatatatta ttgtaaaaag agattatagt
    40501 ttaaaattat gtatatttaa gtaaaataaa cttaataaag ggcatattat tcaaaatatt
    40561 atgaatataa aaaatattac aaaaaagtat tgaaaaaatt cagattatgt agtattatgt
    40621 aaatataaat aaagaaagaa agaggtgttt ccaatgggaa ggttagaaga tgaaccccta
    40681 ataattaaat gattcagtca caatctaaag tgaatataaa aatctattga aagtttattt
    40741 ataagaattg aaaatagtat ctattctatc tttagtgttt gtgagagggt tctggattat
    40801 ataagattac tgtaaagaag taattttgca caataagcat atctgtaaat gaagagtttc
    40861 gtttatataa tgattgtggc tgaatcataa ctataataga tagaatgttt ataatagatg
    40921 attttataaa atactatatt gtaatagctt ttagctttca aataaatatt agcaaaggat
    40981 ggaaatgaca atgataaaac taaatgataa tttataaata tctccttacg atatataata
    41041 attgtaggga gatgtttctt ttttttgtag agtataattt ttctagaaat tctgtttcaa
    41101 tatgtaaaaa gttggtatat ataaatagta taaacagtgt tgctaaaata tggtagatat
    41161 tatataatat aaatggatat gtatatacat tatgagttat ataatttgaa tttaataaaa
    41221 tagaaacgtt gatttatgtt ctgtaatgtg ggcaccttgg agcatattga gttagtggtg
    41281 caaccggcta tgaaattgta tttatttata aatactatta ttttcatagc tttttttatt
    41341 taaaaaatgg ttatatgtta gaaataaatt tggttagtac gtttaaataa ttttacttag
    41401 atttttaacc agatatatta taagtaagta ttaattaaaa aatttaaggg ggaataaaaa
    41461 tgaagttaaa aaagaataaa aaaggtttca ctttagtgga attattggta gtaattgcaa
    41521 ttataggtat attagcagta gtggcagttc cagctttatt tagtaatata aacaaggcta
    41581 aggtagcaag tgttgagtct gattatagct cagttaagag tgcagcatta tcttattatt
    41641 cagatactaa taagatacca gttacaacaa ctgataaagc tggtttaact attttagaga
    41701 cttatatgga gtctttgcct gataaagctg atataggtgg aaaatataaa ttgattaaag
    41761 ttggtaataa attggtatta cagataggta cagatactga aggagttaca ttaacagaag
    41821 cacaatcagc aaaattattg agtgatatag gtaaagataa aatatataca ggtgttacag
    41881 gagataattt tggagacgaa ttaacagata ctacaaaaat agataataaa gctctatata
    41941 tagtacttat agataatact gtgatggact caacaaaata attaaaacta tatttttata
    42001 aagaatattg taaatttaat gaaaaatata atataaaaga caggaagaaa atcttcctgt
    42061 ttttttatac tattttcttt aatgttcaat tatgaatgat gatataattg agatagtaaa
    42121 ggagtgaaac ctgtggctaa aaaagttaga ataggagaca aactggtcga aaaaggatat
    42181 ataacagaag aacagcttaa atgggcacta tcagaacaaa aaaacagtgg aaaaagacta
    42241 ggagaatttc tagtacaaga agggcttata gatagtaact tactaataag tgtattaaaa
    42301 gaactcttgg atatagaaag tatattttta gaagggacag aaatagacac tttagctaca
    42361 aaaatggttc cagaaaatat atgcaaaaga tatactgtat ttccatttaa aattgatgga
    42421 aataaaatat gtctagccat gtcagaccca caagatagag aagcagttca agatgtaagg
    42481 cgtatgtctg gtaaagacgt agagatattt atatcaagta cagaagatat aaacaaagca
    42541 ataggtcatg cttatgcaca ttcagaaata aataaggcaa tgactgagta caacaaaaat
    42601 agaactggtg gagtaagaga aacagtaata cttgaagaag atgtaaatgc tgctccaata
    42661 gtacgattag taaataacat actagaaaat gctgttagaa tggaagcaag tgatatacat
    42721 atagaacaaa gtgaaaatta catgcgtgtt aggtttagga tagatggaat gttaagagaa
    42781 tatatgagga tgaactcagc accatataag gcagtaatca gccgtatcaa gataatgtca
    42841 gatataaata tatctgaaaa gagaatacca caggatggta gaatctattt aaaagtggat
    42901 aataaaccca tagattttag ggtttctaca atgccaacta acagggatga aaagatagct
    42961 atgagggttc ttgataagag taattttatg gttagtaaag aagtactagg aatagacgaa
    43021 catggctcta agatatatga tgaattgata aacactcctt atggtcttat attggttgtt
    43081 ggccctactg gaagtgggaa aaccactaca ttgtattcaa tgttaaatca actaaataca
    43141 gaaaatagaa atctattaac aatagaagac cctatagagt atgaattacc tggtgtaaat
    43201 caatctcaaa taaatgaaaa ggcagggctt actttcgcca gcggacttag agcttttatg
    43261 cgtcaagacc cagatataat aatggttgga gagataagag atactgagac agcagaaata
    43321 gcaattagag cttctcttac aggacattta gttttaagta cattacatgc aaatacagca
    43381 gttggagcaa tttcacgtct tttagatatg gatgtggaaa gttttttaat aacttcatct
    43441 gttttaggtg taatatctca aagacttaca cgaaaaatat gtgagcattg taaggtttca
    43501 tatgaagcag atattggaga aaaaaaggct cttggtattg atgtaaatga atcagtaact
    43561 atttatagag gaaaaggttg tgaaaggtgt aataatactg gatataaagg acgtctaggt
    43621 atatttgaaa tgcttgaaat tactccagaa ataaaagagt taatagattc atctgcaaat
    43681 caaagagaaa ttttaaagat ggctagaaaa caaggtatgg ttagcttaaa agaggatata
    43741 gttaaaaaag ttttaaatgg aaagacaaca gtagaagaaa tgattagaat aattttgatg
    43801 actgattaaa ggatgatatt atgaaaagtt ttaaatacac agtaataaaa gaggacggaa
    43861 aaaagcaaac tgatgtgatt gaagccaacg attttaatga agctagaaat cttcttagaa
    43921 agagaaatct tagagttatt gaaatcaaag aaagcaaaaa taaaaatata agattatcta
    43981 gtagaaagag aaaaaaagac ttaggagctg accagataag ccacttttgt agacaatttg
    44041 ctattatagt atcttctggt ataaatagta tttctggatt agaaacatta gctagaaggt
    44101 caactaacat tacattaaga gaagaaatta atcgtatagt agcagaaata aaagtaggtt
    44161 ctactattgc agattcaatg ctttcatcaa aatcaaagtt tccaaagtta cttggtgcta
    44221 tggtagctac aggtgaagct acaggtaaat tagatgaagt attaaaaagt atggcttcat
    44281 tttatgcaag tgaacacagg gttaaacaaa agcttagaaa tgctgcaaca tatccattaa
    44341 tagttttgat ttcttcattt ataatgattt ttatatttac aacatttatg gtgcctaaga
    44401 tgattaattc aattacaaca gtaggagcaa ctcttccact tataacaaga attgttatgg
    44461 ggtttggtat gtttatgaag aagttttgga taatagtact tttagttatt atattattta
    44521 tctatcagtt taaaaaatat ctaaaaacgt cagttggaag ggctcataaa gatagagtta
    44581 taaataagat acctgtttta ggaaaaggaa taaattgtat ggtagctaca cgattttcaa
    44641 gagcattgta tctatttgta tcaacaggat acccattagt tcaagggctt gattatatta
    44701 tagatagtgt aaataacact atggcagaga agattttagc atcagctaaa gatggaataa
    44761 caagaggaga aggcttagca gaaaatttag agagatatac gtattttgac tctgtgttgg
    44821 tacagatgat agctataggg gagcagacag gggaattaga gaatataagt agacagatgg
    44881 cagaatttta tgagtatgaa tccgagattt atttaaatag gatggcctca atgatagagc
    44941 ctgttttaat aattgcagtt ggtattatag ttgcgatact ggttgtatca atattcatgc
    45001 caatgcttag tatatatgat gccatgtagg agggaaagga caaatgaaca aggtttatgt
    45061 atcatattat ggcgattcta tttccatagt tgagggcaga tataaacacg ataaggataa
    45121 gttttatgta aaaaatttta atgtgttttc aatagaggat attgcacaag atttttctaa
    45181 ggaaaagtat gctctattga gatacgcatt agaaaatgtt aagttaaaat caagacatgt
    45241 agttttttgt ttaaatacaa gagatgtaat tttaaaaccc caaaaacttc ctaatatgga
    45301 caaaaaggat ttagacggat ttatgaagct agagatggac gaaatgatgg ctttggagtc
    45361 agatgaatat gtattttcgt atgaagtatc tagtgaaaca cctgataatt cagatggcga
    45421 tgaatcaagc ttaaatctta ttattggagc tatacaaaag gaagaggtaa atgcaattgt
    45481 agagataatg catgaatttg atttagtatt agatagaata gatacattat caacagctta
    45541 cttaagaatg cttaaaaatt tagactacaa tgatataatg gtaaccaata taagtgacaa
    45601 tagcacaatt ataaatatat ataagaaaga tactttattt attagtgata atatacctat
    45661 aaagataact gctaaagata tggacatgca attattaaat gtagtagaag aatcaaaagg
    45721 tcttatgaat tactattcgt caagaaactt tggtaaggtt acggatacta tattaatatt
    45781 aggaaaaaga tattccaata aattaattta tgaaactttt agctctgcat tttcaagcta
    45841 tgtttctcaa ggccttactg agataatgga tatatctgat atgataactg gagatataga
    45901 tgaagatgat ataaattcaa ttgtagagct tttaggaagt atgatagaac ctaaagggaa
    45961 aagagatttt gaaaatataa actttttacc aatggatata cttagaaaac agataaaagc
    46021 taaacaaatg aaaaacatac tgaaaattgc tccaatagtt attttgattc ttgctatacc
    46081 ttatttatgt ttaatttttt caaataattt agcaaataag gaacttgaaa atgttaatgg
    46141 tgaaataaga aatattgaat ctgcatatta tcagattgga aatatagaaa aaatgataca
    46201 gagtaaaagc gaagaaataa aggtatatga tatgttaatt gggaaaaagg taaagtggga
    46261 aaatttattg gatgatatag ataaaaatac tccaagtaaa gttgaactaa caagtttatc
    46321 aacaacttat caaaatcttg gaactaataa taaagctgat aattcaaaaa gtaataagac
    46381 tacaacagat aaatcaagta acaatgaaac aaaatcaagt acgaaaagtg atagtaatgg
    46441 agataaaaca gataatgatt taaatgaaga taagactaca aatgtgtcag aagcattaac
    46501 tggaaatagt gagactaata gtaataacac ggataaagat gataaaactc cattgtatga
    46561 taagatacca aatgttataa atatagaagg aaatgctaaa gattcctctt atgtaggtca
    46621 atttttatat aaattaaagg gattatacta tttcaaggat gttaaattac atagcataaa
    46681 aagtaatgca gaagattcta actatacatt tagtatgaca ttatacctga aagaaggtgt
    46741 attaactaat gaataaagat atatttaaaa aagatataaa agatatattt aaaatggaag
    46801 ttagtctaaa agggattctt ataaaggtta taattttatt agctatttta tcatatggtt
    46861 attttggact ttaccctcaa tatcagaaat atattgctac aaaaaattct gtaaaacagg
    46921 ctactgaaaa attaaatata tataaagaga aaactgcact tatgccaaaa tatgaaaaac
    46981 aacttgagga agttgaaagt gaattaaaag aaaaaagcaa aaatctttta tatgatatgc
    47041 aagatggtct ttttttaata ggtttagata aaaaaatgaa ggcttataat attgacttaa
    47101 ccagttatga cgttggaaat gttaaagaat acgaacattt ttatggtata tcaacaacaa
    47161 taagtgttag aggtgattat agaaatgtca aaaaattaat ggcttattta gaagaacaaa
    47221 aaaatgttac tcaaatacta gattatacaa tgacttcata tatagaacca gaaaaagaag
    47281 aggaagaaac aacaaacaat aaggatttaa ttaaaaatgt gaacataaat aaagatacaa
    47341 aaatatactg ggtggaaggc gaaaataagt ggcatttata taaggattgt ccattgataa
    47401 aagagggaga gattataaaa aatgacaaac ttttagatag gtctactaat tatctatgta
    47461 atacttgtgt acttagagct gcaacagaaa aagaagcaaa aaaagaagtc gtagctccaa
    47521 aggcagaagg tgtagtagat gctacattta aatttataat gtacactaaa gagaatacta
    47581 caatgatact tgatacagat aatccatctt catggagacc aggaaaatat aatccattta
    47641 agtctagtgc gaaataaagc taagtaagct ttaaagatag gtgatgagtt tgtacaaaaa
    47701 taatgaaaaa ggtcttactt tattagaagt aataatagct gtttttatac tgacaatagt
    47761 tttaagtatt tcttataaag tgttcaatgg tataacatca gcagtaaaaa agcaacagat
    47821 tattacagat gctcaagtaa atattaatct aattaataag tatctaaata gagatttgga
    47881 aaactgtaaa gagctaacta aaactggttc aggtaataat tatgaataca atatagagat
    47941 gccagataat gttgtaaaat atgaagtttc tatagaaact aaaaaaaata cagaggtata
    48001 ttctgtaacg agaatccaaa acaatacaat tgatacagaa aatgaagtta gagaagagat
    48061 aatctataat caaccactag ttcaaaataa taaagaaatg aaggaaacac catttaaaat
    48121 agaaaagcaa actggtaaat ctatttatac tgtaagtata tactataatg aatcggtgca
    48181 agaaagtcat aaaaatagca atttaaataa caaaacttat acatttgatg ttatgtcaag
    48241 aatagggtaa taagaattta ttaaaaaata agtaggttga taaaatatga gtaaaaagaa
    48301 tagtgaaaga ggattttcct taattgaagt gttagtagct atggctatta tgggaattgt
    48361 actatttgca ttttttaata ttatcaatac taataacaaa gcaaacacta aaaatgacac
    48421 agatataact tccttaaact atgtccaaag tgaaatagaa aatctaagag aaaagataaa
    48481 aagtggagaa tttgattttg atagtttaga taaactagaa gatggaactg tcgtatatga
    48541 aaaattaata gataaatcaa aaaaagttgt atatgataaa gttcttagtg aaggtgatgt
    48601 gagcttatat gatactccat atgaaaagat tacaacaata aaagatgaag atggtaattt
    48661 aatcgacaaa ggaaatatta caaataagat aaagactatt gtagaagata aaagtggtca
    48721 gatatataaa atagctgtaa ctgggaaaag catgaatgac tattcaagta aaaaagaggt
    48781 taaaattgta actgaaatat ttaaagataa ataattttac ttgggggtga gattttgagg
    48841 aagtggaata aatttaaaag tgaaagaggg gcagctttag ttttagtttt ggttgtagta
    48901 gcattgcttt ctattgttgg attgatattt tcaaatcaga tagctaatag aataaaatct
    48961 acaaagacta ctaatgaagg tatacaagca aagtatttag cagagacatg tgtggaaaat
    49021 agtattgata aagcatatga aaaattgtat gatgagcttg agaaaatgga taatgagttt
    49081 aaaagtgaaa atcaagaaaa atccatatct aggtcaaaat taagaaatat atcagatgaa
    49141 gattttaata atcaagatga ggaaaatatt gaagcagaaa gacttggata tatgaataat
    49201 ataaatttct atttaaataa agcttcttca gacttggaaa aagctagtat ggaattgaaa
    49261 aagctatatg atttagatat gttggactat agagacattg aatatgtaga tgcaaatatt
    49321 atttcacata gaaattctat cttagaaatt tgcaagaatt atacttctgg agatattagt
    49381 aaaataaatg aatatattct gaaagaagat atagactcaa ctacattgat tgaggcaaag
    49441 ttagtgaata atgatattct tttaaaaaag tttttagaag aaaataaaat tgaaaatgaa
    49501 catttaaatt cagccttttc acatacttat aaggcattag ataacatttc tttggcgatg
    49561 caaaatatga ttgagtatag acatacgttt catatagatg agccaaaagt agaagtatct
    49621 aatgggattc cagactctca acaatattat gaactaatac aaaatcctat aataaatagt
    49681 atggagtata gctggaatag taaatgggat acattagaaa acctattgga aattttacca
    49741 aatcaaactc aaggatttaa ttctttaaga gttcatttga gaaataatgt aagaaaattt
    49801 gagaagttaa gcgataatat atctagtggt aaaaaaaata cagcaaaaaa tttcttaaag
    49861 tataaagagt tattgtatga aatatcagac caatgtaatc aactaaaaag tatgtcttat
    49921 gagaaaatac ctgttaaata tgataacatg gctttgataa caacttttga ctatatacaa
    49981 aatgagcttt tagcagagat aaaatgcaga ttaaaagaat taaaaccaca agaaattgat
    50041 aaaacagaag gtattactat aaaaatacct ttttataagg ctgactacga catgacaaaa
    50101 gaaggatggc ctaaattaaa agaaaatggt tcaggggcgg agttaagctt aatggtaact
    50161 ggtgataaaa atggaataaa agaagtagaa gttacagatg gtaaaaaaaa tattattggt
    50221 ttaggtgttg aagaaaattc aaattcaaag tataaggttg acgccattgt aaactttaat
    50281 ctaaatatag atacaaatgt agttggaaat tatgatataa aagataaaat tttgattaat
    50341 catgatataa gttcatacaa aaaagtaaac taaatataag aagcaactta gtataaataa
    50401 ataataaaat aattttatta tttactacta aaaaaataag taaactaata gaagatatgg
    50461 agagtaaata ttatgtatat ttatgattta ttagagcaag gtataagact aaacgcatca
    50521 gatatacaca taacagttgg aacaaatcct gtagctagag taaaaggtgg atttgtaaaa
    50581 ctaagtgaac aaatattgac atcagaagta acaatgcaaa tggcaaaaga catagcaggg
    50641 gaatctatgt ttaaagtaat agaagaacat ggagaagctg atttttcagc ttctctaaaa
    50701 acaggagaaa gatttagggt aaatgcatat aggcaaaaag gaaattacgc aatagcaata
    50761 aggactataa cagcagaaat tccaacattt gaaaaattag gccttccaga gagtataaaa
    50821 tcttttactg aaaagcataa aggattagtt ttagttacag gtccaacagg aagtggtaaa
    50881 agtacaacac ttgcaagtat gataaatata ataaatgaaa aacaacaaaa acatataatt
    50941 acacttgaag acccgataga atatgtacat catcataaac aaagtttagt aaatcaaaga
    51001 gaagtaggaa ctgatacaga aagttttcat tcagccctta gagctatttt gcgtcaggac
    51061 ccagatgtaa tactaatagg agagatgaga gaccctgaaa ctgtttcaat agcattaaca
    51121 gcagcagaaa caggtcattt agtattttca acactacata cagtaggggc agctaagaca
    51181 attgatagaa tagtagacat gtttcaacca tcccaacagc aacaaataaa aacacagtta
    51241 tctacagttt gtgaaggtgt ggtatcacag cagttacttc ctacagcaga tgggaaaggc
    51301 agaatagcag caattgaatt gatgtttgct actccagcaa taaaaaacct gataagagaa
    51361 ggcaaaacat atcaaattcc aaacatgata caaactggag ttaaagtagg tatgaaaact
    51421 atggaccaag atttaatgga actttataaa aatggaaaga ttacaaaaga tatggcactt
    51481 agtaggtgta ctgaccaaga gtttatgaca agaatgatag gtggagtaaa ctacaatgga
    51541 tattataatc gttaatctat atgtatttat agtgggtata gtgtttggaa gtttctttaa
    51601 cgtctgtatt tttaggattc cagaaggtat atctatttct agaccacctt ctcattgtat
    51661 gagttgtaat actagactaa agccaataga cttaatacca gtgctaagct atttaatgag
    51721 tggcagaaag tgtagatatt gttatgagaa aatttctagt agatatgcta tagtggaatt
    51781 aattacagga cttttatttt taacagtatt tatgttatat ggaatatcta catcaactat
    51841 ttattatttg gttcttgtgt ctttactgat tataattaca tttatagata ttgaccactt
    51901 tataatacca gataaaatat tggtttttgg agctatattt tctatgattt ttaacctttt
    51961 atttaaagaa attccagtta aggattcaat tctaggtgtt tttatttgtg gaggaagtgt
    52021 ctggattata gttcttttga ttgaatttgt aataaaaaaa gagtgtatgg gtggaggaga
    52081 tatcaaacta tttgcaatgc taggttttta catgggtgtt aaaaatggtc ttttgacagc
    52141 cttactaagc gtttatgtgg gagcagtcta tggaatctgt gtaataatta taagtagaat
    52201 aaaaggaaag gaatataatt ctgttatacc atatggacct tttatatcta ttggagcatt
    52261 aataacaatc ttatctggaa agcaattact tgaactttat ttttctatgg ttatatagat
    52321 gatagtcaag ttaaataaag ttttaattta aaaaaatgaa ttaaagtatt taataaggac
    52381 aatattatta ttaaccctat tactaaagtg ctacaaacta tggagtatat aataataatt
    52441 tccttatttt ttgcacattt gataaataaa tctctatgtg ttttttgtga tagagaaaag
    52501 aaaaatttat ataatacgtt ttttatttac ataataactg tagttttatc tgtattaata
    52561 tatctaaaat ttgggattag tgtagaatgt gtacaatata tggttttaat tccattttta
    52621 ataattatat ccattgtaga ttactacaca atatatgtat atgatataac aatagttagt
    52681 ggtataatag ttcaaggtat aatttttttg gcctttttca atatagttca atttgattat
    52741 ataaatcata tatttggact attgataggc tttattatac cttatattat tgctaaacta
    52801 acaaaaggat taggctatgg agatgtaggt ctctatagct tatgttgctt tgcattggga
    52861 aataattatg ggttttatgt gatagtttta tcatttattt tagcgttttt gttttttatt
    52921 attttataca taactaaaat atttaaagat gtagatataa gaaagcaaat tccttttaca
    52981 ccttttattt ccttgtcaac aattttaata atatttacag agtataatat atttaatttt
    53041 tattataatt tgttatacaa atttatataa caggaggtaa gaaatgtacg tagtagtagg
    53101 gttaggtaat ccaggaaaga agtatgagaa gactagacat aacgttggat ttgatgttat
    53161 agatattctt gctaaagaat acaatattag tgttactaaa ataaagcata aagctttgat
    53221 tggtgaaggg agagtaggta ctgaaaaagt attattagtt aaaccacaaa cttatatgaa
    53281 tttaagtgga gaaacattaa tagatatata taaatattat aaggttgatt taagtaatat
    53341 agtagtagta tatgatgata tagatttaga agttggaaag atacgtataa gaaaaaaagg
    53401 aagtggagga actcataatg gcatgaaatc tataactaag tgcctaggtt caaatgactt
    53461 tccaagagtg agagtaggtg tatctaaacc agaagctggt caagacttag cagactttgt
    53521 actttctaga tttagaaaag aagaatctga taacataaat gaagcattag aaaaagcggc
    53581 agatgctatt gactcaataa taagagaaaa tatagatatg tctatgaaca aatataatgg
    53641 atagtgagag ggagatttaa atgaatgatg tttttttata tcctttgcaa aattcaaaag
    53701 agtataaaga tataataaac tgtataaaaa atacaaaagg ctcattattg gttaatggac
    53761 ttttaccagt acaaaaacct catatatcgt attctatatt taatgattta tcacgacaaa
    53821 tgatttttat aacgagtagt gatttagaag caaagaaagt atacgaagat ttaagttttt
    53881 atatggaaga taaagttgaa tatttaggtt ttcaagatat ttatttttat cacttggatg
    53941 caaaggacag aaacgaagaa gcgaagaaat taaaagtatt gttaaaacta gcaaataaag
    54001 aaaaaatcat tttagtaact tctattgagg cagttttaag aaaatacata ccaaaacaag
    54061 ttttgctcga tagtgtatct cattataagg tgggagatag cttagactta gaaaagttaa
    54121 ctgagaaatt agtttcattg ggatatgaaa gagtttcaaa aatagagggg tttggtcaat
    54181 ttagtataag aggtggaatt attgatgtat tttcacttga atatacaaat ccaattcgta
    54241 tggaattatt tgatgatgag atagattcca tacgaacttt tgacgtatat tcacaaaaat
    54301 caattgataa attgcaacaa ttctctataa ctccatctag ggaatttatt tatcccgaaa
    54361 aaactacaga tgcattagtt aaattaaaaa aagaaacaac taaaaatact gatgaaggta
    54421 catttcaaaa tatagattat atatcaagta agacttattt tgaaggtgta gagaactata
    54481 tagattatat ttatccagaa gaaaacaaaa gtatatttac ttatttagca gatgatgcaa
    54541 tagtatttat taatgatata acgagactta aagaaagatg cgaaaattat ataaatgagt
    54601 ttagagaaaa ttataaatta aatcttgaaa gaggtctggc tattaaaaac caaggtaaat
    54661 tgttatatca ctatacagat ttagagtact tagtaaaaga caagtctgtg gtattaaact
    54721 cgctattgcc aaagtctata aataactttt ctataaaatc tataataaat tttgaaagta
    54781 gagaagttcc tacatttaat ggaaaggtag atttgcttgt agaagaatta aatcggctga
    54841 aatataatgg atacaaaata attttagcaa caaatacctt agaaagagca aataaattag
    54901 gaaaagattt attggacaaa ggcttagaaa cgaccatttc taaagataga gatattgaaa
    54961 ttaaatcttc acaagttata attgtacctg cacacataaa cagtggtttt cagtataaat
    55021 ctataaagtt tgttgttata acagataacg aaatgatagg tgtttataaa agagcgtcta
    55081 agactagcaa taaaaaagtt aaaaagggaa agaaaataga atccttttta gatttaagtg
    55141 ttggagacta tgtagtccat gaaaatagtg gtgtaggtag atacacagga attgaacaaa
    55201 ttacagtcaa tgctattaaa aaagattata tgaaaatagt atatcaaggt ggagataatc
    55261 tatatgtgcc aatagaccag atggacaaag tacaaaaata tattggtgca gaagtagaaa
    55321 aagttaagtt aaataagctt ggaacaaatg agtggacgaa agcaaaagca aaagttaaaa
    55381 aagaaattga agatatgaca aaagacttga ttgagcttta tgcaaaacgt gaaaaaatac
    55441 aagggtataa gttttcaaaa gatacacctt ggcaggcaga gtttgaatcg ttgtttccat
    55501 atcaagaaac agaagaccaa ttaaaggcta tagaagaaac taaaaaagat atggaatcaa
    55561 gtaaggtaat ggataggcta gtatgtggag atgttggtta tggaaaaaca gaggtagcta
    55621 ttagaagtat ttttaaagct tgtatggacc aaaaacaagt tgctgtattg gttccaacaa
    55681 caatattggc ccaacaacat tataatacat tcaaagagag gtttgaaaat tatcctttga
    55741 gagtagaagt tttaagtagg tttaaaacac caaaacaaca aaaacagatt attgaagatg
    55801 ctaaaaaagg attagtagat attttaattg gaacacatag aataatatcc aaagatataa
    55861 atttaccaaa cttaggtctt gtagtcattg atgaagaaca aagatttgga gtaaaacata
    55921 aagaagcttt aaagaaaatt aaatctacag tagatgtact tacactttca gcaactccta
    55981 taccaagaac attacatatg tctttaagtg gaataagaga catgagtgtt atagaggaac
    56041 ctccacaaga aagacatcct gtaataacat atgttacaga gagtaaggaa agcgtaattc
    56101 aagatgagat agagagagaa ttaagtagag gtggacaggt attttttgta tacaatagag
    56161 ttgaacacat tgaagaaatg gcaagtatga ttcaaaaact cgtaccagat gctagagtgg
    56221 ctgttgcaca tggaagaatg acttctaaat cattagaaaa tataatccta ggatttttaa
    56281 ataaagatta tgatgtacta gtctgtacta caataattga aactggtatg gacatatcaa
    56341 atgcaaatac aatgattata tatgatgcag ataaaatggg attggctcaa ctttaccaat
    56401 tgagaggtag ggttggaaga agttcaagac aaggatatgc atatcttttg tatgaaaaag
    56461 ataaaacttt aagtgagata gcggagaaga gattaaaagc tatcagagaa tttacagagt
    56521 ttggttctgg ttttaaaata gcaatgagag accttgaaat aagaggagca ggaaatattt
    56581 taggttctca acaacatggt catatggcag ttataggtta tgatttgtac gttaaaatgc
    56641 ttaatgatgc aattaaaaaa gtcaaaggtg aacctattgt ggaggaaatt gatgttgaaa
    56701 tagatttaag tgtaaatgca tacattccag ataattatat caaagatgag ttgattaaaa
    56761 ttgaaatgta taagaaaata gcttctattg aaaacaaaga agacatgttg gatatacaag
    56821 aagaacttga ggatagattc tctgatatac ctaaaccagt ccagacactt cttacaatag
    56881 cttatataaa atcgttatgt aagatattaa aaatagaaaa gataagacaa ttaaaagatg
    56941 aaatattatt agttccaata acaaagtata gaactaaaca gaaaataggt tataatatag
    57001 ttacagaatt agaagaatta ttagaaaaga tgtgcaaggt aaaataactt gtaaatttaa
    57061 gaagggatgt tttaaatttg aaaaaggtaa taacattggt aatagctatg attttggtag
    57121 tatctgtgac tgcttgcagt tctagtaaag gagaaactgt ggcaacagtt gaaggtacaa
    57181 agatatcatc agatgaattt aaaaaaacta tagctcttta taaagattct atggaacaaa
    57241 cttatggaaa agatatatgg gataaggaag ttgaaaaggg tgtaaaatac aaggacaagt
    57301 ttaaagattt aattcttgac caacttataa ctacagaagt aatatattct caagctaaaa
    57361 aagataactt acttcctaaa aaagaggatg ttgaaaaaag ctttaaagaa ttaaaagacg
    57421 ctatgggtaa agatgaaaaa tataaagaac aacttaagaa attaggtata gatgatgagt
    57481 ttttaagaga ccaacaagag aaagatttag caatgcaaaa ctatcaaagt aactttgcta
    57541 aaaagactaa aatatcagat gaagaaatga aaaaatacta tgatacacat aaagatgaat
    57601 ttaaaaaaga tgaggtagaa gcttctcata ttttattgaa aacagtagat gataataaca
    57661 agccactttc agataaggaa aaagctgaag ctaagaaaaa ggctgaagag gctcttaaag
    57721 aagttaaatc aggtgaggat tttgcaaaag tagcaaaaaa atattcacaa gatacttcag
    57781 caagtgatgg tggtaaatta ggattctttt caaggggtca aatggttgct gaatttgaag
    57841 atgctgcttt ttctatgaaa aagggtgaag tatctgattt agttgaaact caatatggat
    57901 accacataat taaagtgaca gacagaataa atgagcaaac atcatttgaa gatgctaaag
    57961 aaactataaa agaccaactg ttgaaaaata aatatcaaga acaaatagaa aaattaacta
    58021 aagaagctaa ggtagaaaaa gatgaaaaag taataaataa aatcacaatc taagacttaa
    58081 aaaaagagta atatgcttaa aaaagctata tctggataag atatagcttt ttttgtatat
    58141 ttttcttaac aatggtaaaa ataaacttaa agtaatttat ggagggatta aaaaatatga
    58201 aagcaacagg tatagttaga agaatagatg atcttggaag ggtagttatc ccaaaagaga
    58261 taagaaagac attaagaatt agagaaggag accctttaga gatattcaca gcaaaagatg
    58321 gagaagtcat acttaaaaaa tactctccaa taggtgaatt aaatgaattt tcgcaagaat
    58381 atgctgaaac attagctgaa gtactaggat atggagtgtt gataacagac ttagattcta
    58441 taatagctgt gtctaagctt cctaaaaaag attataaaga aaaaagtata agtgatgagt
    58501 tagaagcaat aataagtgaa agaacagtaa aatattcaaa agataaaaac attttaccat
    58561 tattcaagga agaccaaaaa gaatatacta gtcaagttat catgcctata attagtgcat
    58621 ctggtgactg tataggttca attgtagttg tttcaaagga taaagataca attgcagaaa
    58681 gtgaagaaaa atctttaaaa attgctgcta actttttagg aaaacaagtt caataatttt
    58741 atcataaaga ccttttacat gaaggtcttt tgaagttttt gtgtaaaata ttgaatatag
    58801 cattaaaaat atggtatatt aaagtttgtt atataaacag tatggaggtt atgttatgaa
    58861 caataacaaa aataaagact cctttctaaa aggagccctt atacttgggc tagcaggtgt
    58921 aatcgtaaaa ataatgggtg gattttttag gattcccctt ggaaacatga ttggttcaga
    58981 aggaatggga tactatcagg ctgcttatcc tgtgtatact ctatttttaa cattagctac
    59041 tgctggattt ccaacagctg tggcaaaatt ggtttcggaa aaagttgcaa ttggaaattt
    59101 taaaggtgca aataagatat ttaaggtatc acatacagtt ttattcatta ccggtataat
    59161 atcattttgt atattatttt ttggagccga ctacatagta acaaacgtaa tgaaaaatcc
    59221 aggtgcgtta tactctatga aagccattgc tccagcatta ctatttgttc ctgcaatgtc
    59281 tgcatataga ggatattttc aagggagaca agatatgact aagattgctg tgtctcaagt
    59341 tgcagagcaa ttttttagag ttgtattagg tcttactttg gcttacttgc ttatgaagag
    59401 tctaggtcag acttttggtg cagcaggtgc tatatcaggg gctacaatag gttcaatagc
    59461 atctatgctt tatttggtgt ttgcttatat gctagggaga aaagagcgta gagcagagat
    59521 agatgcaagc caaagattta aagatgaaag agtgtcttat atttttaaaa agcttttaac
    59581 tgttgccatt cctataacaa taggagcatc agtaatgcca cttgtaaata tgatagataa
    59641 tgttattgta ataagaagac ttatggaagc aggctttaca tacaaagtgg caaattccat
    59701 gtttggtcaa ttaacaggta tggcaatggc cacaataaat ttaccagcag tcataacaac
    59761 tgcaatgagt atgagcttag ttccagcaat ttctaaagca tatgcattag gaaataagtc
    59821 aaaagctaga aaagatacta agagtgcagt taaggtaact ttacttatag tattgccttg
    59881 tgcgtttggt atggcttctt tagcaatacc aataatgggt cttttatttc cacatgaacc
    59941 atcttctgta ggaactattt tgtttactct tactccatgt gtattatttt taggattaat
    60001 acagacattg actggtataa ttcagggaat gggaaaacca atagtacctg taattgcttt
    60061 atgtgttggt atgctatgta aaattgtaat aagttatact ttaacaggta taccagatat
    60121 taatgtactg ggttcagcat ttggtacagt tacagcatac tttgtggcag ccatgattaa
    60181 cttactatat gttaaaaaac acatgaatgt aaacttttct aaaaaagaat ttataataaa
    60241 gccatttata acagttatga caatgtttat aatggttaag ttgagttatg gtgctttagt
    60301 tggattctta ggaaacagca tatctacaat aattgcaata tgtgttggtg gaattgtata
    60361 tgtagtagta atacttggaa taggtggaat taaaaaagaa gagattctaa ctatgccaaa
    60421 aggtgataaa ttatataaat tgttaaaaaa agttaaactt ataagataat ataggaatat
    60481 atatgcaaat aaaggaaata ctatacaaat agtaaatctc cttatttgta taataatata
    60541 aaaataaagt gaaatttgct aataggagtg atgttatggg taagataagt attgtaggtc
    60601 ttggaccagg agactattct cttataagcc aaggtgtgtt agaatcttta ataaatagcc
    60661 ctaaagtttt ttttagaaca gagaaacatc caataattga taaacttaaa gaaactatac
    60721 aatacacttc tttagactac ttttatgaaa aagaggaaaa ttttgataat gtttatttga
    60781 aaatatctga atttatcata gaagaatcag caaagggtga cctagtgtat gctgttcctg
    60841 gtcatccaag agttgcagag aagactgtaa gtataataga gagattagcc aatgaaaagc
    60901 acatagcagt agaaatattg ccttctatga gctttgtaga cgctatgttt aactatttgg
    60961 ctatagaccc atctgaggga tttaaactgg tagatgcttt tgaaatagaa aattcatata
    61021 tagacttgga tacaagtatg ataataactc aggtatatga taaatttata gcatctaatg
    61081 taaagttaaa acttatggaa cattatgact ataatcaaga agtatgtata gtaaatggag
    61141 ctggtgtcaa agatttagaa agtaaaaagt ttataaagct ttgtgaatta gacagaaatg
    61201 aaaacttttt tgactattta actagcttat atatacccaa aagttctaaa aagatgtata
    61261 atacagtaca tgacttagaa ataatagtta atacacttag aagtccatct ggatgtgaat
    61321 gggataaaaa acaaacacat caatcattaa aaaattctgt tatagaggaa gcatatgaac
    61381 tttgtaatgc aattgataat aatgatatag atgaaatggt agaagagtta ggtgatgttc
    61441 ttttacaggt tatattccat tgtcagatag gaaatgagga gggctacttt gatttaaaag
    61501 aagtagtaaa tggcatatgt aaaaaattaa ttcatagaca tcctcatata tttagtggtg
    61561 caaaattaga tatgtctaag tttgagaaaa cttgggaaga attaaagaaa gaagagaaag
    61621 gcgaaagtac tataacagat ggccttagaa ggataccaaa acatttacca gctcttatga
    61681 aggctagtaa agttcaacat aaagcagcac ttgtcggctt tgattgggac aatgtagaag
    61741 atgtatttaa aaaaattgaa gaagaatatc aggaattact tgacgaacac agggtcggga
    61801 atataaaata cataaaggaa gagctaggcg atttattatt ttcgatagta aatctagcta
    61861 gatttttaga catagactca ggagaagcct tgaactgtac tacagaaaaa ttcataaata
    61921 gatttgactt tatagaaaaa agtgcaatga acttgaataa aaaattagaa gacatgacac
    61981 ttgaagagat ggatgagttt tggaatcagg ctaaaaaaca ataaaattgt ggaaggaaat
    62041 ttgtcaaaaa tctagaactt ttatcacaaa gatagaagtc tatattataa acatttttag
    62101 gaggtaaata tcgtgaataa agctgaatta gtatcaaaga tggcagaaaa aagtggatta
    62161 acaaagaagg aagcagaagc tgcgttaaac gcatttatga gttctgttca agatgcacta
    62221 gtaaataatg aaaaagttca attagttgga tttggaacat ttgagacaag agaaagagct
    62281 gctagacaag gaagaaatcc aagagatcca gagcaagtta tagatatacc agcttctaaa
    62341 gcaccagttt tcaaagctgg aaaaggatta aaggatataa taaatggata attagaaatc
    62401 ttgtgaaaaa gtgtggataa atttgccaca ctttttctat agaaccaagg aaggtgataa
    62461 ttatgagatt agataaattt ttaaaagtat ctaggattat aaaaagaaga actgttgcta
    62521 aagatgcatg tgataaaggg attgtcacta taaatggaaa agttgctaaa tcttcttcag
    62581 aggtgaatat tggagataca ttagaaatac aatttggaga gaagaagatg aagtttaaga
    62641 taaatgaagt aaaagagcat gtattaaaaa atgatgcaaa agaaatgtac aaaattttag
    62701 aataaaatta atagtcctct agtatattaa tagtagtatt attgaaatat ttactggggg
    62761 gatattatgg aacagaacat aactttgaaa gatagatcaa agctggttat ttcgggagtc
    62821 gagcacatat actcttttaa tgacaaaaga gtagagctca aaacttctgt aggcgagatg
    62881 gtaattgaag gcgaaaacct agatatgagc aagctaagta tagacgaaaa tataattagc
    62941 atagatggaa ctataaattc tatggtatat gcaaagccta aaaagccaca agagagtttc
    63001 ttgaaaaagg tatttagata gatgatacct tttactcaag atgtaagcat tttttatgct
    63061 actatttatg gtggaatact cataggggtg ttgtttgatt tttatagagg gctaagaggg
    63121 aattttaaat tcatcaatta ttttgctata atctttgatg tattgttttg gtttctagct
    63181 acggttataa tattcgtaac aataaacctt acagaatttt ttgatttaag atattatcat
    63241 tttgtggctt tgtttattgg ttttatttta tactataaca ccataagtaa aattgtttta
    63301 tcaattatca ataaaataat tcgttttgtg agaaattctt ttaaaaaagt tacacattac
    63361 atagtcagtt ttttaaataa tttgtattac gttataatct attcactaca cctactattt
    63421 gatattatat tttatatacc aaacatattt atagcaacaa gaaaaagtat aaaaagaaaa
    63481 tcaaataaaa aattaaagaa caagaaaaaa tcaaaaccta agaagaaaaa aaataaaact
    63541 aaaaaaaggg tgtaggaaaa atgaacttaa gaaaaaaatt ttcaggacag attattgtta
    63601 tcagtttatt tttaggaata tcaattttta gtatgatgac aggatttgta tttgagtata
    63661 caaaagctaa ggaatataaa aaagaaatag caagtctaaa taaacaatta aaaaagactg
    63721 aaatacaaat aaacagctta aagaaagatg aaaaatcata tgaaggagac ttagaggata
    63781 tagcaagaaa aagattgaat atggtaaaac caaatgaaac agtttatgta gacataaatc
    63841 gttgattaaa acttgctaat aagtttacag atgtattgat tttaaaattt aagatttaat
    63901 aaaaaagtca ttcagttaag gatggctttt tgtttttatt gaggagggaa tttcataatg
    63961 aaagtaggag ctatagatat tgggacaaac tcaatgagat tattgatagc agattataga
    64021 gatgggaatt ttataaacag aaaaaaattt gttaatacaa ctagaattgg ttatggtgtg
    64081 gatagtaaag gatatataaa agaagatgct atcaaaagaa atataaaagc attaaaagaa
    64141 ttttctgata agtgtaatga tgaaaagtgt gaaaaaattt attgtatggg gacatctgct
    64201 cttagagaca gtaaaaatgg agattacttt gttaaattag ctaaagaaga aactggaata
    64261 gatgttgata tagttacggg aatagaagaa tcaaatttgg gctttaaggg tgttttagaa
    64321 ggaatacaag gtgatgatac tattattgtt atagatattg gaggaggttc aacagaattt
    64381 attgtaggtg attcagaagg aattaaattt aataaaagtg agaatgtagg tgctcttagg
    64441 atgacagaga ggtttttgaa gcacgatatt attgaagatg aagagtttga agctatgagt
    64501 tcatttatat atgatgagat tgacaaaacg ttaaatcata taaaagacag aggattaaaa
    64561 actcttatag gtataggagg tacgattaca tcattatcag caatgaatca agaattagag
    64621 atttactcta tggaaaaaat acataatagt aaaatacaca aaaaagaaat agaagaaatt
    64681 ctacaaaaat taataaagat gacattaagt gataaaaaga acttaaaagg gctacaagaa
    64741 aaacgtgcgg atattataac tgctggtgta aaaatattga atataataat ggaaaaatta
    64801 gaaatagaag aaataaccgt aagtgaatac gataatttgg aaggcttaat atgtcaaaag
    64861 tcaaaaaaaa tgtattaata ttttttgatt tttaaaaccg attatgacaa aaaaaattac
    64921 tcctctttgt tacaattctt aatataaaca aaagaggagg tttttttatg caaagaagtg
    64981 tagcagttgt gaagaataag actgtaaaac caaatgtcat aaaattaata agcggatata
    65041 ttgattttac tacggcggca ttcgctgtga tgggattttt acttagtagg tctattatag
    65101 tagactctgt agctccttta ggaattgcct tttttatatg tgcatcaaag attgataagt
    65161 acaagatacc tgtattcata tcaacattat taggaatatt gttatcatct aatgattttg
    65221 gaaatgtagc aaaatatgct gtgtgcctta caatatttat ggctatgaat aaaaaattaa
    65281 aattatcaga ttcaattgct aaggttgcat ttataggtgc aataatacta cttccaatct
    65341 ccatgggaca agctttcttt tcaaataggt atgtatatgg tcttcttata gcaggagtag
    65401 aagcaataat aatgtttata tctatatatg tgttttctta tgggataggt ttaatggcca
    65461 atgtcaacaa taggatgtct gtacggacag aagaagccat atcaataagt ttactgctaa
    65521 cctttagcat aatgggaata ggagatatat ctctgtttgg aatatcaata aggaccattt
    65581 tatcgaccgt attgatattg ctgacctcaa tagtaggtgg agctaccatg ggagcatcta
    65641 gtggtgtaat tattggtgta gcatccattt taaataatat gacatcagct gtttatatgg
    65701 ggatatattc tttttcagga ttaataagtg gagcatttaa taaaataaat aaatatttct
    65761 gtatactagg atatattcta agttggacaa taatatacct atatacttct ggtattactt
    65821 ctaatatgat gcaattaaga gatatactat taggttgttt gatagtacta gtattgccag
    65881 agagattatt taataagatt gaaaaattaa taaaaagtaa tgtggcttca aatgaaatcg
    65941 tatacgatta tattatgaga agcaaaaacc taactaatag cagattgaac agtatttata
    66001 aaacttatga tgaccttgca gatacatttg ataagataag agaaaaagac aaagtgctag
    66061 accaaagaga catagctaat gtaatagata tgattcataa tgatgaatgt aaaagttgta
    66121 gtatgagaag aatgtgctgg gagtcaagat ttaatcatac atacactatg atatataaca
    66181 ttcttgaaaa aattgaggag aaaggggagt taagtctaaa cgatatacct aaaaatttta
    66241 gaaaggaatg tatgaaacca gagtcaatag tgaaaatatc aaatcactat tacaaaatgt
    66301 ttgtattaga ttatgattgg agtgtgaagt tttcagaaag tagaaagtta atagcaaatc
    66361 agataagaag tatttcaaaa tccattaaat ccttatctca agatttagaa ggcgacataa
    66421 tgctagatat agaaaaggaa aaaaatatat atgaacagtt agaaagatat gatataacag
    66481 ttgataaagt aagttactta acaaaaagta acagtgagtt tgaaatatca atagaaaaga
    66541 aaacttgcca tgatggatgt atgtgtgaag ataaaattgt aaatataatt tcagacctag
    66601 taggggaaaa tatgtctgtt agaaaaatag gatgtcactg tttaggaggt aaatgcaagg
    66661 caacattcgt taaatctcaa aaatataagg ctgttacaga agtttcagca atgtcaaggg
    66721 atgggcatat cctttgtgga gacaattaca catacatgga gataaatgat ggtaaataca
    66781 tgatggctat aagtgatggt atgggaaagg gtaaaaaagc atatgaagaa tcttctgcca
    66841 ctattgatat actggaaaaa atgatagatg caaaaattaa agatgagata gtcattgata
    66901 ctataaacaa tatgttgttg ttaaaatctt cagaagagat gttttcaact ctggatttgg
    66961 gaattttaga tttaaaacga ggttgtttag aaactataaa gatgggagcg tgttctactt
    67021 atataaaaag agaggatgga gaagttgact taatatcatc atcatcatta cctgtgggta
    67081 tattatcaga tgtaaaaatt gatagaaaaa atgtaaaagt taaggaagga gactatgtta
    67141 taatggtttc tgatggaatt gtagatgcag gaagaaataa caatttagga gacaattggt
    67201 taatatactt cttaaagaat atagagacta caaatccaaa ggaaatttca aatttaatat
    67261 tggatagagc attagagtta caagcgttac aaatcgaaga tgacatgact gttttagtta
    67321 cgaaaatatg tacaaaataa ggtttacaag attatgtgta taagatgtgg ataacttgtg
    67381 tataatatgt taatagactt ttgaaaaaag tatagttatt aacaaaaata acatataaat
    67441 caacaaaatt tgttgataag tatggcagaa atgttaataa aatgtaaaaa aagaaaaaac
    67501 aaaagctatt atcaaaagag attcatgttg aaataactaa atttctaagt aaagaaaacc
    67561 tgtgaatatg ttgattatta tgtggataac tattaattcg atatttattt atatagtatg
    67621 aataattgaa taatatatct aaaaaaagcc atcctattat taagtaaact tattgaaagg
    67681 atggcttttt atgaatagaa aattgtgcaa agcaataata cctttattta tttctatttt
    67741 ttgcatgtta ataataagta taaaagctga ccaaggatat caaaagaata atgacagagc
    67801 aattactgtc atgaataata atgatactga agatgatgct gaaaaaaaac aagaaataga
    67861 ctatgaaaaa acatgttgga atttgcaatc tttgtttaaa agtgatgacc aatggaaaaa
    67921 agaacttaag agttttgata aagatactaa agagttgaaa aattacatag gtaaagtaac
    67981 aaaatcgcca acacatttgt cttttgcctt gaacattaaa gaaaaacttg atataagact
    68041 aaataaactt tctgcctatg taaaattaaa acaagatact aataaaaatt cgtataagta
    68101 cttagatatg aatgatagta tgagtaaatc ctatgggaat tatatgggga tttgttcaga
    68161 tttagagtta gaaatactaa aattatcaaa caaagattac aagaaaatta tttcaaataa
    68221 aaatataaat aggaaatatg gtgcatattt aagagatata agaaggaata aagtacatta
    68281 tttggatgat aaatcagaag atattctaag caaagtatct tcaataagta gtcttccaag
    68341 tcaagtgtat gaattattta gaaatatgga tagaaaaact aatttaacac cagctcaata
    68401 tgcgagtgaa ttagagtcat cagatagaga aaatagaaaa aaagcttatc aagatgaact
    68461 tataacttac aatgataata taaatacaat tgcaggttta attactggtc aagttaaaaa
    68521 gaatattttt tattctcagg aaagaggtta tgagtcttct ttagaaatgt acctggaagc
    68581 tgataatgta gatgaaaaag tatacaataa tttgataagg actgtaaata gtaatatgga
    68641 cagtctacac aaatatatag atttaagaaa aaaagtatta aaattagata aggttcattc
    68701 atatgatatg tttgtgccta tggttaaggc tgttgataat aatattaatt atgaaaaggc
    68761 acaaagtata gtatattcag cgttgtcacc tttaggaaaa gaatacaatg atgtagtata
    68821 taaagctttc aatgaaaaat ggatagatgt ttattcacat gaaaataaag taagtggtgg
    68881 atactgctta tctgtttatg aaaatcatcc atatatactt ttaaattata ataattcatt
    68941 aggttcagtt tcgactttat cacatgagct tggacatgct gtatatgaat acttaagttc
    69001 taagaatcag aattatttta attcaaatcc gtctatattt actcacgaag ttgcatctac
    69061 aacgaatgaa gcattacttt acgagatgct tataaaagaa gctaaaggca atgatgaaaa
    69121 agcttattat ataacacagt atttagactt gataaaagat actctttata cacaaactat
    69181 gtatgctgaa tttgaaaaaa ctatacacga gttagtagaa aaaggaaaaa gtgtaaacgc
    69241 attagtatta aatgatgttt ggggacaact tcttaaaaaa tattatggac aaagctatga
    69301 attagaccaa ttatctaagg tcggatgggc tagaatccca catttttata atagtttcta
    69361 tgtctataaa tatgctacag gttgtagtgc aggagtaagt tttgcccaag acatcctaaa
    69421 gaatggttca gataactata tgagctttct taaaaaggga agttcagatt atccaataaa
    69481 cttgttaaaa tcaagtggca taaatttaac taatacaaaa cccatagaaa atacaatcaa
    69541 aaaatttgat agtttagtag cagaacttga aaagctatta taaacattat tgtaatccac
    69601 atggtaaata tatcgaatta atgataaaat atactaaaag tttaaagtcc tatcaagata
    69661 ggacttttta tttattaatt agtgggagat gattctatgc aagttaaagt taaaaaggct
    69721 gtaataccag cagcaggttt aggaactaga tttttgccag ctacaaaggc acaaccaaaa
    69781 gagatgttac caatagttga taagccaact ctacaataca taatagaaga agctgtggcc
    69841 tcaggaatag aggaaatact aataataaca ggtagaaata aaaaatctat tgaggaccac
    69901 tttgataaat ctgtagaatt ggaacttgat ttagagaaaa aaggtaagaa agaattgttg
    69961 gaggtagtac aaaacatatc taacatgatt aacatacatt atataagaca aaaagagcca
    70021 aaagggttgg gagatgcaat ttattgtgcg aggcatttta taggtgatga gccgtttgca
    70081 gtaatgttag gggatgatat tgtagataat gatgtacctt gtctaaaaca actaacagat
    70141 gcatatgagg aatatagaac tacaatattg ggtgttcaaa aggtaaatca agaagatact
    70201 aataaatatg ggataataga agcaaaaaat atagaaggta gagtttacaa ggtaaaagac
    70261 atggtagaaa agccagagtc aggaaaagct ccttcaaata ttgctatttt aggtagatat
    70321 ataataactc ctgaaatctt tgatattctt aaggatttac caccaggtaa aggtggagag
    70381 gtacaactta cagatgcttt aaaaatatta tctaagaaag aagctatgta tgcatacaat
    70441 tttgaaggca agagatatga tgttggggac aagctaggat ttttagaagc tactgttgac
    70501 tttgctctaa agaaagaaga ccttaaggaa gattttataa aatatttgaa acatgtatgt
    70561 agtgaatttg ataaaaataa caatgtgtta tacaataata cagatgaaaa aatagattta
    70621 attgaagtca atgaagctag agaacttgaa attcaaaaat aattaatgaa aggtgatgta
    70681 tggtggcaaa atcaagtcag aaaagaatta atagaataat agctgttggg attgtgggaa
    70741 tcctcgtaat aacgagtata acagctgttt tgagtatgat tgcaactatg taataagata
    70801 aatgacagca gttgatatac ataaatataa aaaccatata taacttgatg tagtcaaaaa
    70861 cttacaatat tttagttata tatggttttt agaatttata aatgtaaaaa aaaattttta
    70921 taatagttgc atattttaaa ggaaaatatt attataagat ataaatatag tgataaattt
    70981 ataaaaacgt gctaagattg gacttgaaat acagtaatat agtaggtaat aatgttttaa
    71041 attttattta ttgaccataa tatataaata atgatattat tagacttaac tgtttaaata
    71101 aaacttttct ttttcatgcc ttcaatttcc aaaataagta tgtatataaa tgaatatata
    71161 gatgaggagg atttttttga ttttagatga taaagtatta gaaggattag gtagtaagac
    71221 cttagttgag ctacgagaga tagctaaaga attaaaaata aaatcaatta ctacatataa
    71281 gaaaaatgag ttaattgaga ttataaattc caaaagtaaa aatgaggaaa aagtaaacga
    71341 agagactaaa gaaaaaaatg aagatattaa agaagacata aagaatagaa aagaaaatat
    71401 agagcgtgaa agtatagaaa aagaagttga atataagagc cctaccaaat catacaacaa
    71461 gaaagaaata gatacccaaa atatttccca aaaccaagaa catagaaatc aaagaaatga
    71521 ctataataag acaacgagtg taaatgatag taataagtca tcaaatatat ctaatagaat
    71581 ggtcagaaat aataataaaa actattatat gcctaaacaa gttgatgaat ctaagatagt
    71641 agatgaattt aacacatcaa aagaggatga agtagtaggt gtacttgaaa ttctgccaga
    71701 tggatttggt tttttaagag gttcaaatta tttgtctact gaaggagatg tttacgtttc
    71761 accatctcaa ataagaagat ttaatatgaa aacaggagac aagattaagg gaataactag
    71821 acatccaaaa agtggagaga aatttagagc acttttatat gttcaaaaaa taaatgatga
    71881 aaaccctgac acagctatac aaagaaatgc gtttgagaca ttaacaccaa tatttccaga
    71941 agaacgactt acactggaaa ctaatagaaa tgaaatagct acaagaatta tagatttaat
    72001 ttcacctata ggaaaaggac aaagaggatt gatagtagca cctccaaaag ctgggaaaac
    72061 agttctttta aaaagcgttg caaatagcat agctaaaaat catccaaatg ttgaacttat
    72121 agtactcctt atagatgaaa gaccagagga agttactgat atgaaagaat ctattgaagg
    72181 agacgttata tattctactt ttgaccaagt atcaagtcat catgtcaagg ttgcagagat
    72241 ggtgttaaat agagctcaaa gattagttga acatggtaaa gatgtagtaa ttttactaga
    72301 tagtataact agattggcaa gggcatataa tcttacaata tctcctacag gtagaacttt
    72361 atctggaggt attgaccctg gtgcacttca tggacctaaa aagttctttg gtgcagcaag
    72421 gaatattaga cagggtggtt ctttgacaat attaggaaca gcattggttg aaactggttc
    72481 taggatggat gatgtaatat ttgaggaatt taaaggtaca ggaaatatgg agctacattt
    72541 agatagaaaa ttagcagaaa aaagaatatt ccctgcaata gatatttaca agtctggtac
    72601 aagaagagat gatttattgc ttgatgatga agaaaagact gctctttgga gattaagaag
    72661 agaaatgagt aataattcag taatggaaat tacagataaa gtcattgaac ttataaagag
    72721 aactaaggac aataaagagt ttgtaaaatc aataaagaat ttgtaaaatc aataatacaa
    72781 atgcaaatat ggattatata aactaataga aaaatcactt gaatggcata ataagttgtg
    72841 ctataataat gtagttgata atgtaaaaag aaagttaata taattaattt ttttaaataa
    72901 agagaagagg tgactataat gcaaaaggaa atacaaccaa aatacaatcc agttgaagtg
    72961 cgttgtgctt gtgggaacac atttgttgct ggttcaacta aggacgaaat aaaagttgaa
    73021 atatgttcag agtgccatcc attctataca ggaaaacaaa agaacataga aaaaggtgga
    73081 agaatcgaca aattcaagaa aagattcaaa atggactaat ttttataaaa gtggagttgg
    73141 aggaagccaa ctcctatttt attacaaaaa aacattcata ttctacttta aattgtcttt
    73201 ttgtattata ataataaata tgtaaaattg agtattctaa atacaataaa atgaggtgag
    73261 tggatggcaa aacaagctgt aggtgggcaa gctgttattg aaggtgtaat gatgcagtca
    73321 aaagacaaaa gagcggtagc tgttagaaaa agtgacggag aaatagcact aaaagaagat
    73381 agaataaaaa gttgggtaag agataagaat atagataaga taccttttgt tagaggttct
    73441 tttgttatga tagatacaat gattcaaggc ataaaaagct taaacttttc ttcagagttt
    73501 tttatggaag aagctgaaga ggataaattt gatttattta taaagaaaat ttttaaagat
    73561 aaggcaaatg atataattat aatattttca ttggtcatag caatgttact ttctgctgga
    73621 ttattcattt ttatacctac attggtagga ggagcttttt ctaaagtaat gcctaatgat
    73681 tttatgctta atttaataga aggaatcata aggatagcta tattatttgc atatatagta
    73741 ttgatttcac gaagtaagga tatagaaaga gtctttcaat atcatggagc agaacataaa
    73801 tctatatatt gctatgaaaa tgatttagaa cttacagtag agaatgctag aaaatttaaa
    73861 agattacatc ctagatgtgg tacaaatttc ctatttatag ttatggctgt atcaataata
    73921 ttgtttgcat tttttggttg gccaaatcca attcttagaa tatttatgag aattatatgt
    73981 gtgcctatag tagcaggttt atcttatgag gtaattagag ttcttgggaa atatgataat
    74041 ggatttacta aaattattgc atatccagga atgatgttgc aatattttac aacaaaagag
    74101 cctgatgatg agcaattaga agttgctttg gaagcattga aagcagtagt agattagaga
    74161 aaaggatatt tgttatgacg ataaaagata taattattaa atattcagat aaactaaaag
    74221 atataagtga tactccaaga ttagatacag agttattgtt acaaaaaaca ttgggtgttg
    74281 atagattata tattcactta aatctgaata aagagctaac tgaagaacaa aaaacaaaat
    74341 ttatgggttt tgcagaagaa agattaaatg gaagaccaat agcatatata gttgaaaata
    74401 gggagtttat gggattagat ttttttgtta aggaaggcgt attgattcca agaccagata
    74461 cagaaacttt agtagaagaa ataattgaaa tatgtagaga aaaaaaagat gtaagtatat
    74521 tagatatagg aactggttct ggagctatta caataagttt agcaaagtac attgaaaatt
    74581 ctaaaatcat gtcttttgat atatcagaga cagcattaga aatagctaaa aaaaatgcta
    74641 ttataaatga agttggtgaa aaaataaagt atattaattc tgatttattt acagcaataa
    74701 gtgatagtaa cataaaattc gatatcatag tttcaaatcc accatatatt aaaaaacaag
    74761 atatagaaac tctgcacaaa caagttaaag attatgaacc atataatgct cttgaaggtg
    74821 gagaagatgg attagacttt tatagaagaa taacagaaca aggtaagaaa tatttaaata
    74881 agtgtggaat attagcatat gaagttggtc ataatcaagc tgaagatgta ataaatatta
    74941 tgaaaagtaa tggatataaa aaaatataca caaagaagga tattcaaggc attgatagag
    75001 ttgttatagg ttacaatata tgatataatc aacaattgat atgttacatt taatcgaggt
    75061 gaaagtatgt taaaaaaatt agaggtattg gaagatacat ataaagactt aagtgaaaaa
    75121 ataggtgatc cggatgtaat aaatgatcaa aaagtttggc agaaatatat aaaagaacat
    75181 gctgacttgg aacctattgt tatgaaatac agagagtata aaagcgtttt agatagtata
    75241 aaagaatcaa aagaaatttt acaagaagag tcagatgaag aattaagaga attagctaaa
    75301 atggagttag ctgagatgga agaaaaagta gcacctctgg aggaagaaat aaaaatacta
    75361 ttattgccta aagaccctaa tgatgataag aacgttatag ttgaaattag aggtggagct
    75421 ggaggagatg aagcagctct atttgctggt gatttattta gaatgtactc aaggtatgct
    75481 gaaagaagaa gatggaaaat agaattattg agtgcaagtg atactggagt tggtggatat
    75541 aaagaagtat cttttatgat aaaaggtaaa ggtgcttatt caagattaaa gtatgaatct
    75601 ggagttcata gagttcaaag aataccatca actgaatctg gtggaagaat acacacatca
    75661 acttctactg ttgcagtatt accagaagtt gaagatgtag aggttgaaat aaatccaaat
    75721 gatttaagaa tagatgtttt ccgttcttca ggtaatggag gacaaagtgt caatactact
    75781 gactctgctg ttagggtaac acatatacct acaggtgaag tagtatcttg tcaagatgga
    75841 aaatcacaat taaaaaataa agagcaagct ttaaaaatat taaaagctag actttacgat
    75901 aaagcattgg cagaacaaca caaagatata gcagcagaaa gaaaaagcca agtcggaaca
    75961 ggagacaggt cagaaagaat aagaacatat aatttccctc aaggtagaat aagtgaccat
    76021 agaataaatt taactttata taagttagat gcattcttag atggagatat agatgaaatg
    76081 atagatgctt taattactgt tgaccaaaca gaaaaaatga ctgcaatata agtaatgttt
    76141 taaagaagct gtttcttcct agaaattatt ttctattttg aaacagctat tttgcatttt
    76201 aggtcatgtt atcatattct attgtatata attgttatat acaagtatag gagggttata
    76261 tgatactaaa agtaacaata attgggcttt tggcaggtgt tatagggaca ggattaggag
    76321 gagtaatatc agccattttt aaaagagagg tcgataaata tctaagtttt tttatgggat
    76381 tatctggtgg aataatgttg gctgtagtgg tgtttgattt aatgaaagaa tccatggaca
    76441 aaatggggat aatcaataca gttatattta cgtttgttgg agctctcata actatgtaca
    76501 taaaaacaaa attagatgtg tctggaaata tggcatctgg atatcttata ttcataagta
    76561 tattactaca taatttacca gaaggactag ccattggttc ttcttttatg tcaactgaaa
    76621 gtttaggtat tacacttgct atagttatag gtctacataa tataccagaa gggttagcta
    76681 tggcattagg cttagtttgc aataaaatga aactaagtaa agttattttg tttactgtaa
    76741 tagctggatt acctatgggt ctaggaagtt ttttaggtgt ttattttgga ggagtattta
    76801 cttctcttat aggagtattt cttgctacag caggaggtac tatgatgtat gttgtattgg
    76861 aagaaatttt tccacattca aaaagtgtgt attgtataat tggtttcttg ttaggtacaa
    76921 tgattgtaaa ttatatataa aattaaaatg aaagcaggca tacaaaagat gaaaactatt
    76981 ataagtaata ttgatataaa taatattgat tatgaggaaa taaaaataca agcaaaactt
    77041 cttagagaag gtaaaacagt tatttttcca actgagacag tatatgggtt gggtgcaaat
    77101 gcattagatg aaaatgcagt aaagaagatt tatgaagcta aaggaagacc tagtgacaat
    77161 ccattgatag tccatatata tgaaaaagaa gaagtatatg acttagccaa agatataagt
    77221 gataaagcta aacttgttat agaaaagctt tggccaggac ctataacaat tatattaaat
    77281 aaaaaagata taattccata caaaactagt ggagggcttg atacagttgc aataaggatg
    77341 ccttctaatg ttattgccag ggcaataata aaagaagctg gtatacctat tgcagctcct
    77401 tctgcaaata tctcaggtcg cccatctcca acaaaagcaa aacatgtata tgaagagatg
    77461 aatggaagag tggatggaat agttttagga ggagacagta attttggatt ggagtcaact
    77521 gtattggatt taacagaaga gactcctatg atactgagac caggaagtat aactaaagaa
    77581 gttttagagg aacttcttgg agaagtaaag cttgacccat cattaagtaa aaaagaagat
    77641 aatcaaaaag ctaaagctcc tggaatgaaa tataaacatt attctccaaa tgcagatgta
    77701 tatataatat ctggaaaaag agaaaatgta gcaacaaaga ttaatgatat gataaaatct
    77761 aatagagaca aaggtctaaa gacaggtgta atgtgtatta gtagaaaccg agagttttat
    77821 gatggagaag taatcgattt aggaaactct cttgaagaag ttgcaagtaa tctgtttgat
    77881 gctcttatag aaatggacaa aaagggtgtt gatgtcatat attcagaaga gttccctaag
    77941 actggagttg gacaagcaat tatgaataga ctactgaagt cagcaggata caaagtgata
    78001 aaggcttaag agggagttgt aaaatatgaa tatacttatt gtgtgtacag gtaatacttg
    78061 tagaagtcct atggctgagg ctatactaag gaaagcaatt aaagaatctg gaagaagtat
    78121 tgaagaatat tctatatcat cagcaggtat atctacagca aatggaatgg gtgcttctga
    78181 aaattctata gaagtactaa aagaaatcgg tatagactta tcaaatcata gaagtaaagt
    78241 aattactaaa aaattaattg atgaatcaga tataatacta acaatgacta aatctcataa
    78301 agaaatttta gtacaagcag ttccaaaatg caaagaaaaa gtgtatactt ttaaagggtt
    78361 tgcaaataaa aatgaggaag atatatctga cccatttggt ggaaatttgg atatttatag
    78421 aagcactatg agagaaataa tgtattctgt caacgaaata gtaaaaaaaa tatgaaacgg
    78481 aggataaaca aatgaagata ggattaggct gtgaccatgg aggatataat ttaaaaaaag
    78541 aaataataag ctatttagaa agtaaaggca tagaatgtgt agattatgga actaataatg
    78601 ctacagattc tgttgattat cctgtttatg gagaaatagt tgcaaattca gttataaata
    78661 aagaagtaga ttatggaata ttatgttgtg gtacagggat aggaatatct ttagctgcta
    78721 ataaggttcc tgggataaga tgtgcagttg tatcagatgt attttctgca aaaatgtcaa
    78781 aagcacataa tgatgcaaat atgttatcat taggcgaaag agttttagga aaaggtctag
    78841 cacttgagat agttgaagca tggattaata cggattttga aggtgataga catgctagaa
    78901 gagtaaacat gattaaatca atagaagaaa aacataataa ataataaaaa ttacagtttt
    78961 atcaggagga attatcaaaa tgagcaaagt ggtagagaca aaccatccat taatacaaca
    79021 taaattaact ttaatgagag ataaaaatac tggttctaaa gactttagag agcttttaac
    79081 tgaaattgca atgttaatgg ggtatgaaat aacaaaagat ataccattaa aagatgtaga
    79141 aatagaaact cctattcaaa aaacatcatc taaagtagtt gcaggtaaaa aattagcaat
    79201 aattccaatt ttaagagcag gtcttggaat ggtagatgga ttagtgagct taatgccagc
    79261 agcaaaagtt ggacatgtag gactatatag agacccagaa acattaaaac cagttgaata
    79321 ttattgtaag cttcctcaag acataggaga aagagatata atagtagttg accctatgct
    79381 tgcaacaggg ggttctgctg tagcagctat agatttactt aagtctaaag gagctaaaag
    79441 tataaaatta gctaatttag tagctgcacc agaaggtata gcagaagtgc aaaaatatca
    79501 tgatgatgtt gatatatatg ttgcatcagt tgacgaaaga ttaaatgaac atggatatat
    79561 aattcctggt cttggtgatg ctggagatag attgtttgga actaaataaa aataaataac
    79621 tataaatatt tattagggac tttcttatat agtgtatata attttatgta agaaggttct
    79681 tttttatata ttttttctca aaataggaat tattgaattg ataaatttct cgaattgaga
    79741 ataaaaagtt tttaccaatt aaaaaagatt gcttatttta caaggtttta tagaatagta
    79801 gtctatttta atgtggcatg ttagttgctt acgattaaga ttataggtat taagtgtatt
    79861 agttaaattg agaattgaat attaataata ttattgggag tggtaataca tgaagaattg
    79921 tatagtagta agaggggctg gagatttagc aacagcagtt attcataaat tacacaacag
    79981 tggttttaaa gtagttgcgt tagaaataga agagccatta gctataagaa ggcaaatttc
    80041 tttttgtgag gctgtttatg aaaaaaaagt aactgttgaa ggtgtagaat gtatattttg
    80101 caatactgaa aaagaaatag aagaagtttt atctcaacat aaagtagcct tgattataga
    80161 cccaaaagga gaaaaattat ctaaattaaa tccaatcgtt ttggttgatg gaatactcgc
    80221 taagaaaaac ttaggtacaa ctaaagatat ggcaccactt acaatagctt taggtcctgg
    80281 attttgtgca ggagaagatg tagatgttgt tatagagaca atgagaggtc ataatctagg
    80341 aagaataata actaatggta gagcagaaaa aaatacagga gtaccaggag caataaaagg
    80401 tttttctaaa gagagagtta tgcattcaca gtatgatggc ataatggaaa atgtatgtaa
    80461 gataggtgat atagttgaaa agggagacct actttgctat attaataatt atgaaaaaaa
    80521 acatgaagtt agagcaacaa tatctggagt ccttagaggt ttattaaagg atggagcaaa
    80581 ggtaaacaaa aatttaaaaa tactagacat agaccctaga aaagaagaag ttaagaatgc
    80641 ttttacaata tcagataaag ctagatgtat agctggaggg gttttagaag ccatactaaa
    80701 caatgggatt tatccccaaa attaatttat attagataaa gctattaata ttttattaag
    80761 atgatataat aaatttaata gattaaagag agcatatgac gggtatttaa aatttaaatg
    80821 gtaaaaatgc tcttttttta ttggacattc aattaacatg tgtatataat ataaaaataa
    80881 gtatttattt aggttgaaat ctaataaata tataatacca gtacataagc aaagaggaga
    80941 aaagtaaatt atgagaccat catgggatga atacttcatg gaaattgcag aagtagtgaa
    81001 aaagcgttca acttgtatta gaagacaagt aggagctgta attgtaagag acaaacaaat
    81061 attaacaact ggatataatg gttctccgag aaatcttgaa cactgtgaaa atattggatg
    81121 taagaggcag gaattaaata ttccctcagg agaaaggcat gaattatgca gagcattaca
    81181 tgctgaacaa aatgcgataa tacaagctgc tcataatggt attagtgtag atggggcaac
    81241 tttgtatgtt actacaagac cttgtgtttt gtgtgcaaaa atgtgcataa atgcaggtat
    81301 attgaaaatt gtttatgaag gtgattatcc agatgatatg tctacagaat tattaaaaga
    81361 agcaggaata gaactcataa aattttagtg gataaaattt atatgacaat aaatgtcaaa
    81421 ttatgacact gaaatacaat ggtatcaaat gattaaaaga aagtatttga aaaatcatca
    81481 gattagtagt aagatatatt ttataattaa ataaatttat gagatagatt aattacatgt
    81541 tatttatttt ataataatga gggatactat ttatgagtaa aagaaataca catacagaaa
    81601 ttgcaaagtt gtttagttta ataagccaaa taggattgat gattgtaata tcaatattag
    81661 gatgtacttt cttaggaaaa tttttagata gtaaattgaa tactactcca gttctgacaa
    81721 taatattttt attgttgggt gttggaggtg cttttagtgg tgtttataaa actctaatag
    81781 tatatacacg aaggaagtga tatattggat ataaaattac ttaaccaggt aaggtcagta
    81841 acaaaaggta tagtaatatt tgatgtagtt ttaattgtgc taatgttgat aacatcaaca
    81901 ttaagtaaac cagtattatt aggacttata tttggctcta taatagctat gttaaatttt
    81961 agattattgg cgatatcact ggaaaaatca gtgacatttc ctgctgggaa ggcacaagct
    82021 tatgcatcag cacaatatgc tgttagatta tttataatgg cagttgttct aattgcatca
    82081 gctacagtac cacatttaaa tataatcgga acagcattgg gattattgag cacaaagttt
    82141 gtcatattat caaaaaactt tataaataaa ttaaagagga aggaggcata agtatgaatc
    82201 aagcgcatta ttatctcata ggaaacttta agattagtga aacaatacta gtaagttggg
    82261 gaataatggc ctttttagcg atagcatctt attttttgac tagaaactta aaaaaagttc
    82321 caactagtaa agttcaaata ttcttagaat ttgcagtagg tggtcttgct aaaatggtta
    82381 cagatgttat gggtaaaaat acagtaaaaa gaatgccata tatgatacca tacataggaa
    82441 gcttgttttt atttttcgca tgttcaaatt taagcccatt acttggatta aggtcaccaa
    82501 caaccgactt agatacaact gctgcatggg caatgattac attttttatg atttattttg
    82561 caggagttaa atttaagggg ttatcatact ttaaagaatt ggctcaacca cttgccataa
    82621 tgttaccaat caatattata ggtgagttag ctagaccaat atcattaagt ttccgtccat
    82681 ttgggaatat tttaggtgga acaataataa tgggtctgtt ttatcaactt ttaggtttta
    82741 tttctagttt aataccagga ttatcaatac caattggaga aatattaata ccagtcccat
    82801 tacacttgta ctttgactta tttgcaggat tgttacaagc atatatattt ataatgttaa
    82861 caatggtatt tatatcaagt gcaggagagt tagattaaga aatcaactta tattaagata
    82921 aaaataaaat aatttaaaaa attaaagttt taaggaggaa ataattatgg aaacagcaat
    82981 agtagcggca gcatcagcaa taggagcagg gatagcagtt gcaacaggta taggtgcagg
    83041 tataggtcaa ggtatagcag cagctaaagc tgcagaagca gtaggaaacc agccagaagc
    83101 taaaggtgat ataacatcaa ctttattact aggagttgct atagcagagt cttcagcaat
    83161 atatggtttg gttatatcaa taatacttct attcgtaaat ccattcttta aatacttagg
    83221 aatgtagatt tagtccttaa atattttgag ataggtttat aggtaaatca tctcaaactt
    83281 ataatcatga gatgaacttt atcatctcgt gattataagt agttatgatt tatggaaagg
    83341 aggataatta tggaaaaagc actagtaggt ataacgtggg aatttgtgtt ccaaattgtt
    83401 aatactttta taatattttt acttctgaga aagcttttat tcaagccagt attaaatata
    83461 attgaatcaa gagaaaatga tattaaaagt gatttggtag aaggcgaaaa agcaaaaaat
    83521 gaaggtttag ctctgaaaaa agaatatgag tcaaaaatca attttgccaa agatgaaggt
    83581 caagaaatca taaaacaagc aactataaga gcagagcaga aatcagatga tatagtaaat
    83641 actgcaaaga aagatgctct tgatataaaa gaaaaagcaa acaaagatat agaacaagaa
    83701 agacaaaagg ttataaatga aatcaaaaat gatatatcta acatagcact acttgcagca
    83761 tctaaagtta ttgaaaaaga tttagataaa tctaaacatg aagaattgat agaaaacttt
    83821 ataaaagagg taggggaagc taaatgataa atgtaatagc aaatagatat gccgaagccc
    83881 tatttcaatt aggagaagaa gaaaattcaa ctgatgtctt attcaaagaa ctagaaaaag
    83941 tagtagatat gatgactaaa gttagtaaag atttctacaa agttttaaaa tcaccattag
    84001 tttcaaaatc agaaaagaaa aacttggtag aaattatttt tagtaaagaa gtaagttcta
    84061 acataaaaaa ctttttaaaa gttttagtag ataaagatag aatatcatat ttagaagata
    84121 tcgaattagc ttataaagaa ttattaaata agaaaaacaa tgtaattgat ggagtagcaa
    84181 taagtgctat tccaatgagt gaaacagata ttaaagaact tgaagtcaaa ctttcaaata
    84241 aatacaacaa aaatgttact atagaaaatg ttgttgacaa gactatacta gggggagttc
    84301 tagttagaat tggaaatgaa caaatagatg gcactgtgaa aactcgtctt gataagatga
    84361 aagaaaagct atctgaagta atatcttaag aatggcggtg aacccatgaa cttaaaacct
    84421 gaagaaataa gttctataat taaacagcaa ataaaaaatt atgagaataa agttgagttg
    84481 acagatacag gtagtgtttt aacagttggg gatggtatag cgagtgtata tggattagaa
    84541 aaagctatgt ctggtgagtt gctagagttc ccaggtgaaa tatatggtat ggcacttaac
    84601 ttggaagaag aagtagttgg agctgttatc cttggagatg acagtgaaat aaaagaaggc
    84661 gatatagtta agagaactgg aagaatagtt gaagttccag ttggagaagc tttaataggt
    84721 agagttgtaa actcactagg tcagccaata gatggaaaag gacctatagc gtacacaaaa
    84781 actagaccag ttgaatctga ggcacctggt ataatagata gaaggtctgt ttatgaacca
    84841 ttacaaacag gaatcaaatc aatagattca atgataccaa ttggtagagg tcaaagagag
    84901 ttaataatag gtgacagaca aactggtaaa acatctatag ttattgacac tatactaaat
    84961 caaaaaggaa aagatgttat ctgtatatat gtagcaattg gacaaaaacg ttctactata
    85021 gctcaattag ttagctcttt agaaaaaggt ggagctttgg attatacaat agtagtttca
    85081 gcaacagcat ctgaatcagc accacttcaa tatatagcac catatgctgg agcagctatg
    85141 ggtgaagaat ttatgtacaa tgggaaacat gtacttatag tgtatgatga tttaagtaaa
    85201 caagctgttg catatagaga aatgtcattg ttacttagaa gaccaccagg acgtgaggca
    85261 tatcctggag atgtattcta tttacattca agattacttg aaagagcagc taagttatct
    85321 gatgaattgg gtggaggttc aatgactgcc ttgcctataa tagaaactca agctggtgac
    85381 gtttctgcat atataccaac aaatgttata tctataacag atggtcaaat atacttacaa
    85441 ccagagttat tctattcagg tgtaagacca gcagttgacc ctggtatatc agtatcaagg
    85501 gttggtggtt ctgcgcaaat taaagcaatg aaaaaagttg caggaacatt aaaacttgca
    85561 tattcacaat atagagaact tgcagcattc tcacagtttg gttctgactt agatgaagat
    85621 actaaaaaga gacttgctca aggtgaaaga atcgttgaga tattaaaaca aggtgagcat
    85681 caaccaataa aagttgaaaa tcaagttatg ataatatatg ctgttataaa taatcattta
    85741 gaggatattc cgatagataa tatagctaga tttgaatcag aattgtatgc atttgtagat
    85801 aataattatc cggaaatatc aagaaaaata ttaggtggag aagacttcac tcatgattta
    85861 acagatgcaa taaatgaatt taaagaaaag tttgttgttg aagtataatc ctttttaaaa
    85921 aaggaggtaa attaattggc aggagctgga atcaaagcaa tcaaaacacg tatgggaact
    85981 gttgaaagta caaagcaaat aactaaagca atggaattag ttgcatcttc taagcttaga
    86041 aaagcaaaag aaaaggctga agattcaaga gaatatttta atactttata caatacagta
    86101 aaagatattg cccaaacaac acgtggaatt agaaatgaat ttttaaaaga aagagaagta
    86161 aaaaataaat gctatgtagt agtagctgga gacagaggac ttgcaggtgg atacaattct
    86221 aatgtattaa aggaatctgt ctctcatatg aaaggtaaaa aggaaacagt gattactgtt
    86281 ggaaagaaag cacatgaatt tttttctaaa agaaactaca atatagcaaa agatataaat
    86341 agtgttgaag cttgtggata tgaagatgcg acagaaattt cacaaactat tattgacctg
    86401 tataaaaaag gtgaagtaga tgaagtttat attgcttata caaaatttaa atctgcttta
    86461 tcacaagaag ttgaaatttt gaaattgctt ccattagtct ttgaaaaaga tacagacgaa
    86521 caaggaatgg cagtaaaaga agaaaaacaa aatagatcaa aagtacaata tataccatca
    86581 gcagaagcag ttttaagtta tattgtacct cagtttatat caggtacagt atatggtgga
    86641 attttggaat cttttgcatc agagcaaggt gctagaagaa ctgcaatgga atcagccaca
    86701 gacaatgcga atgaaatgct atctaattta gagttaagtt ataacagagc aagacagtca
    86761 gctgtaactc aagaaataac agagatagtt ggtggagttg aagctctaaa atagggaggt
    86821 taggaaatgg caaatgtagg taaagtagta cagattgtag gagctgtact agatgttaag
    86881 tttgatagtg aacaaagcct acctaactta ttaaatgcgt tagtaataaa gttaggagat
    86941 aaagaaatag ttgcagaagt tgctcaacat ataggtgatg atactgtaag atgtatagct
    87001 atgagtgcaa cagacggact tgtaagaggt atggaagttg tagatacagg agggccaata
    87061 agtgttcctg ttggagatga aactttaggt agaatattca atgttcttgg aaaaccagtt
    87121 gatgggaaac cagctccaaa atctgcacct aaattaccta tacatagacc agcaccggcg
    87181 tatgatgaac tagaaactac agcagagata ctagaaactg gtattaaggt agttgactta
    87241 ctagctccat atctaaaagg tggaaaaata ggtctatttg gaggagcagg agtaggaaag
    87301 acagttctaa tacaagagct tataaacaat attgctaagc aacatggtgg tatttctgta
    87361 ttttcaggag taggagaaag aacaagagaa ggtaacgacc tttatggcga aatgagtgag
    87421 tctggagtta taaataaaac agctctagta tttggtcaaa tgaatgaacc acctggagcg
    87481 agaatgagag ttgctttaac tggacttaca atggcagaac attttagaga tgagcaagga
    87541 caagacgttt tacttttcgt tgataatata ttccgtttca cacaagctgg ttcagaagtt
    87601 tcagcacttc taggacgtat gccatcagct gttggttatc agccaacatt agctactgaa
    87661 atgggtgcac ttcaagagag aataacatca actaagaaag gttcaataac atctgttcaa
    87721 gcagtatatg taccagcaga tgacttaact gacccagcac cagctacaac attctctcac
    87781 ttagatgcaa aaacagtttt atcaagacaa atatcatcac tgggtatata tccagcagtt
    87841 gaccctcttg aatctacatc aaggattctt gaccctagta tagtaggaaa agaacattat
    87901 gaagtagcta gaggtgtaca atcaatactt caaagatata aagaacttca agatataatt
    87961 gctatacttg gtatggatga attatctgat gaagataagt taatagttgc acgtgctaga
    88021 aagatacaaa gattcttatc tcaatcattc acagttgctg agcaatttac aggaaatcca
    88081 ggtcaatatg ttcctgttaa agagactgta agaggattta aagaaattct tgaagggaaa
    88141 catgatgact taccagagtc agcattctta tttgtaggaa caatagaaga cgctgttaga
    88201 aaagcgaagg gaagtatgta gtcatggcca gtgaattttc attgaaagtt gtaactccaa
    88261 gtaatacttt ttatgatgga gatgttgaaa tgatagtagt tagaactaca aaaggagaca
    88321 aaggggtgtt gaaaggtcat ataccatttg tttcaggtat acctgtagga actttaaaga
    88381 taaaaaaaga gggaagtttt aaagaggcga aaatagcaga aggattcatt aatgtaactc
    88441 aagataaaac tgtcatattg acagaatctg ctgagtggat ttaataaatt aatttagagt
    88501 ataaaaagtc attttgacca aaaaaacttt tgggtaaaat ggcttttttg tgttttggtg
    88561 ttaataaaat aacgataaaa ttgtaagttt ttagtgataa taaattcaca aaatgtttaa
    88621 atttactgcc aaattatgtt gtaattaata agataaagaa gatttagata gcttttatgt
    88681 aagtgaaaaa gtcttcatat aagaaataca tataaaattt ttataaaatt taaaaaattt
    88741 gcttagttgt gtagtataat aaataatata atagatttgt atataatatt cattacaaat
    88801 aattttaaaa gttacagttt tattataatg attattaaat taagataagt aacataaact
    88861 aaataataat gtgtattatc gatagtaaat ttataaattc attattaatt attgaaagaa
    88921 gtattataaa ttttctggag gaacaatgaa tatatttgat attggcgtag atataattga
    88981 aattgataga ataagaaagg ctgtagacaa aaataatagg tttttggaga agatatttac
    89041 agatagagaa atagagtatt ttaattctaa gaattttaaa gcagaaagta tagcaggtaa
    89101 tttcgcagcc aaggaagcta taagtaaatc tataggtaca ggaattagag tgtttaattt
    89161 taaagatata gaagttctca gagatgaaat gggaaaacca atagtaaaaa cttataataa
    89221 tctagcaaaa atgtgcatag attataatgt tttagaaata aaagtttcaa tatcacattc
    89281 aaaagattat gctatagcaa atgcgataac cataattaag gactaaggag tgattacatt
    89341 atgatggata aaacagcaaa agaaataatg acaacagatg taatagtagc aaaacaagat
    89401 gatagtatag cagatgtagc taatatgcta attgcagaaa aaataggagg tctgccagtt
    89461 gtagattcag agaatagagt tgttggaata atttctgaaa cagatattct taaaaaagaa
    89521 aaatatatag aagcacctct ctatataaat ctattacaag gattgatttt cttagatgac
    89581 ttaaaaaaag ttgaaaaaga tataaaacaa gtagctgctt ataaggttgg agaacttatg
    89641 tctaaagata taataaaggt tcatgaagat gataagtttg atgatgtagc taatgtaatg
    89701 attaaaaaat caataaacag agttcctgta gtagatgatg acaacaaact taaaggtata
    89761 atttgtagat atgatataat aaaagcttta tacaatgaat aaactgaagt aggaggtgtg
    89821 atgtgagaaa aaagtggacc atagtatgta ttatgttctt ggcactggtt ataattgtaa
    89881 taggatgcca aaaacgacag tccacaaaag aagaagtata caaagatttt caaaagcaga
    89941 tttctgatat gaattattac agttgtaaag ctgaagtaga agtagttgga aataaaagtc
    90001 cacacaatta tgttttaatt catacttata aaaaaaccga taactataaa ttagaagtaa
    90061 tttccccaaa acatttaaaa gggaaaagta tagaatatca aggtgataaa atattagtta
    90121 aaaatccaaa gattagtgat gtagtggagt tacctaatac aggaaaaaat aatcaatatc
    90181 tttttgtagg agactttata aaaaactatc ttcaaaatga ggagatgaaa gtaaagttat
    90241 ccaaaggaca tttggtttta gagactttta ttcctgggga taataaatat tttaacaagc
    90301 aagtattata tgtaaatgct gacacaaaaa atcctgaaaa aatggaagtg ttagataaag
    90361 agggagtgcc aagatttaca gtaaaataca aagattttga atacagaaac taagggggac
    90421 taaagacatg caaaaaataa cagtgcctac atgggcagag ataaatctag ataacttaag
    90481 atttaactta aataatatta aaaatttatt agaagaagat attaagattt gtggagtaat
    90541 aaaagctgat gcatatggac atggtgcagt agaagttgca aaattgctag aaaaagaaaa
    90601 agtagattac ttagcagtag caagaactgc tgaaggaatt gaacttagac aaaatggcat
    90661 aacacttcct attttgaact tgggatatac tccagacgaa gcttttgaag attctataaa
    90721 aaataaaata actatgacag tttattcttt agaaacagca caaaagataa atgaaattgc
    90781 aaaatcttta ggagaaaaag cctgtgttca tgttaaaata gactcaggga tgactagaat
    90841 aggtttccaa cctaatgagg agtcagtaca ggaaataata gaattaaata aattagaata
    90901 tatagattta gaaggtatgt ttactcattt tgctacagct gatgaagtaa gtaaagagta
    90961 cacttataaa caagctaata attataaatt tatgtctgat aaattagatg aggctggtgt
    91021 aaaaatagct ataaaacatg tatcaaacag tgcagctatt atggattgcc ctgatttaag
    91081 attaaatatg gtaagagcag gaataatatt atatggtcat tatccatctg atgatgtatt
    91141 taaagataga ttagaattaa gaccagccat gaaattaaaa tcaaaaatcg gacatataaa
    91201 acaagttgaa ccaggtgtag gaataagtta tggactaaaa tacacaacta caggtaaaga
    91261 aacaatagct acagttccaa taggatacgc agatggattt actagaatcc aaaaaaatcc
    91321 aaaggttctt attaagggag aagtgtttga tgtagttggt agaatatgta tggatcaaat
    91381 aatggttaga attgacaaag atatagacat aaaagttgga gatgaggtta tactatttgg
    91441 agaaggcgaa gttacagctg agcgtatagc taaagactta ggaactataa actatgaagt
    91501 gttatgtatg atatcaagaa gagttgaccg tgtttatatg gaaaataatg agcttgtaca
    91561 aataaacagt tatttgctaa aataaaacca tgatattata atctgggagg cgattttgtg
    91621 tacgataaga gtaaagaaaa aatagaagtt actttacctg actctctgat ttctgaagtt
    91681 gatagtatag ttcagatgga gaacagtaac agagaagatt ttgcaaaagc tgcttttcag
    91741 ttctatataa ctcagaaaaa gaaaattcat attaaagaat ctatgaaaac gggttataga
    91801 gaaatgggtc aaattaatct gtcactagct gaattaggta tgacagttga agaagtatct
    91861 tctgatgata aaaatgaagg gaagattgcc caaggtgagt actaattgtg aaataaagcg
    91921 tggtgattta tattacgctg atttaagtcc agttgttggt tcagagcagg gaggcgttag
    91981 acctgttctg ataatacaaa atgatgtagg taataaatat agtcctacag ttatagtatc
    92041 agctataaca tctcagatta ataaagccaa gttacctact catgtagaga taagttccaa
    92101 tgaatatggg cttaataaag actcagtaat tcttttagag caaattagaa ctatcgataa
    92161 aaagagactg agggaaaaaa ttggttgtct agatgaaaat atgatgataa aagtagatga
    92221 tggacttcaa ataagtttag gattgtttac tttttaaaga gggatttgtc ttttattaga
    92281 caatcccttt tttcttttaa atatctctta aggtttaatt ttaatgtact atgttaataa
    92341 aattaaaaat aacgcaaaaa aatagcataa aagtgatata ataatatgga attgatataa
    92401 aattacgaac tcaagggagg taattgcatg agagaccata aaggattaaa tgagattgcg
    92461 cgtatcataa gaagagatat agtttcaatg atacatagag ccaaatctgg acatccagga
    92521 gggtcattat cagtagttga aatacttact gcgttatact ttgatgaaat gaatgtggat
    92581 tcttcaaatc ctaaaatgga ggatagagat agatttgtat tatcaaaagg acatgctgca
    92641 ccagcattat atgctacatt ggctgaaaaa ggttattttg ataaggaaga actgaatgga
    92701 ttaaggaaga taggaaggat gttacaaggt catccagaca tgaaaggcac gccaggtgtg
    92761 gaaatatcta ctggttcttt aggtcaaggt ttttcagttg catgtggtat ggctatggca
    92821 tcaaagttgg ataatgctcc gtggaatgtg tatactttgc ttggtgatgg tgaggttcaa
    92881 gaaggaattg tttgggaagc tgctatgagt gctgcacatt ataaacttga taatttaatt
    92941 gcttttttag ataataatgg acttcaaata gatggagata tagaaagcgt aatgagttta
    93001 ggttcaatag ttgataaatt taaagctttt ggttggaatg taattgagat agatggacat
    93061 gattttgacc aaatatttgc ggctcttgat atagctaaat caacagttaa aaaacctaca
    93121 atgatagttg caaaaactat aaaaggcaaa ggaatatctt ttatggaaaa tcaagcagga
    93181 tggcatggga cagctccaag tgatgaggag ctagaaaaag ccttgcttga attaggaggt
    93241 gctgacaatg agtaaaatgg cgacgagaga agcatatggt aaagcattag taaaattggg
    93301 tcaaataaat gacaatgttg tagtattaga tgcagattta tcaaagtcta caaaaacaca
    93361 tgatttttac aagtcatttc cagatagatt ttttaatatg ggtatagctg aacaaaattt
    93421 aataggcgct gcttgtggat tatcaactgc tggtaaaata ccttttgcaa gcacttttgc
    93481 tatgtttgct acgggaaggg cttttgagat tataagaaat tcagtttgtt atccaaagct
    93541 aaatgtaaaa atatgtgcta ctcatgcagg tcttactgtt ggagaggatg gagcatctca
    93601 tgaaagtgtg gaagatattg ctataatgag agctatacca aatatgacag ttcttgttcc
    93661 agctgatgga gttgaaacag aaaaaattat ttttgaaata gctaagtata atggacctgt
    93721 ttatgttaga ttagggagaa gttcagtacc agttttattt gatgaagatt ataaatttga
    93781 aataggaaaa ggtacagtct taagagaagg aaaggatgta tcaattatag cttgtggaat
    93841 tatggtaaat gaagctctat tagcacaaga aaagttgcaa gaagaaggta taagtgctag
    93901 agttataaac atgtcctcga taaaacctat agacaaagat ttaatattag aatcagcaaa
    93961 agaaacgaat gctattgtaa ctgtagaaga acatagcata attgggggat taggttctgc
    94021 tgtaagtgag gtagtaggag agtcttgtcc aaccattgta aagaaagttg gaattaaaga
    94081 tacatttgga gaatctggta ctccaaatga attgttaaaa aaatatgaat taacttgtga
    94141 tgacataata aagactgtta aagaagctat tattgcaaaa agaatgtaag agatataaat
    94201 tattcatgtt tgttaataat ataatatatt taaaagagag gtataaagtg ttatattaat
    94261 ttatatctct ctttttttta tatgatatca atatatcaaa aatgtaataa aatattcaaa
    94321 tttttacaaa aatagagaaa atattcaaat atatattgac tattcagaaa aatatgacta
    94381 atatataatt tatagagaaa ctaattttat atataatgac tacttagata aaagaatcta
    94441 aaaaaattat gagaggagga gtagggtata aaatcagatt ataagtttta agttattata
    94501 ctaaaaagct ataaaacagt tatcatgtat tttatgttaa aggaaattgt aggtagttta
    94561 tcgaattgtt taatcagaag aaaaaatttc acatggggag gtaactgaga tatgtcagaa
    94621 aaagtaaatg ttaaaacagt catcagtttc gcaggtgcgt atgtagcaac agtaatcggt
    94681 tctggatttg caacaggaca ggaaataatg caattcttct ctttttatgg ttttgcaggt
    94741 attattggtg ggataatttc aatggtatta ttctcatgga tgggtgcttc agttatgtca
    94801 aaaggtaaag agcttcaact taaagaacct atcaaaattt atcgtgttta ttgtggtaag
    94861 tatttaggaa tattctttga atggtttgga cctttattct tatttggtgt tttcgtagta
    94921 atgatttcag gagcaggagc aactttaact gaatactatg gattaaatcc atttgtaggt
    94981 agagtaggta tggcagtagt agcattatta actgtttcac taggtcttga taaattatca
    95041 aagatactag gtggaatagg gcctataata ataatcttta cacttttagt tggtggtata
    95101 agtttagcta aaaacatagg taatatagga gaagctgcac aagttcttag cactgtaaag
    95161 atagctaaac cagttccaaa tgcctatcta tctggtgtaa tatatactac ttataacaca
    95221 attgttgtta tggcattctt aactggatta ggagcaagtg ctgctaacaa aaaagaagct
    95281 atttgtggtg gtatattagg tggagtagca cttatggctg cagctataat gatgcactta
    95341 gctattcttt ctgatatagg aaacttatat tcaaaagcaa taccatcatt attcttagca
    95401 gataagattt caccagtaat tggagtttta ttctcaataa ttcttatatt aggtatatat
    95461 acaacagctg tacctttatt atggtcagta actaatagat ttgtagatga caaacatcct
    95521 aagtttaaat taataacttt aatagcagct atattaggtc ttataggtgg cttcctacca
    95581 tttgataagc tggttggtat tttatatcca tatactggat atatgggcgt cataatactg
    95641 gtttgtgttc tttatagaca gattacaaaa acatctggat atcaagaagg aatcagtgac
    95701 aaataagtat tttttaatat tgtaaactca agagctatat gaaaacaatg aaaatgtttt
    95761 catatagctc tttttatttt ttagctcgtt tattatgaaa tagaaaaaac atgtttttta
    95821 gttacattac atatatttat aattatgtat aaatatatac taatcaataa tttagagtct
    95881 aagataagtt tataaatcat atatttagaa tatatgggag gagtgataag attgaatgta
    95941 aagtttaata ttaaaggtat aatttatgga gttatagctc ttgtattcgt tataggggga
    96001 tttatattca taccaagtat gtttgtagag aaatctaaac ccatagatta tacagtatta
    96061 caaagaaatt caataccaga aaagatatta gatgtgatgg ataagtatac aaatgaagaa
    96121 agagcattag cggctaaaat cgataacaaa atatacatta tagtgactag aggaaataat
    96181 aaatatggta tagaaatgga caaaatagaa agtgtggttg aggaaggaaa ggatgttttg
    96241 agagtcaaga taaagtataa agataaggaa gattcttttc catacatagt tgttgaaaca
    96301 aatatgagtg aacttccaga tagaatagaa ttaaatgcga cgaaataaga aggtatttta
    96361 taattaaata actgcatatt gtacaataaa gtcatggttt ttattaatgt aagtaaattg
    96421 tgtatggttc ttattgttgt aaaagccatg acttaaaatg cttataaagt aagatattaa
    96481 cagtagtatt tattactaca ttaaatgggg tctggaaata cttaatattc taactatttg
    96541 gagtgataat tctagtttca gtaactatgt agtctaattg tgcatcatga gtttcttttg
    96601 gaatagaatc gaatatctgg aagtcaaatg ctatgccgat agttatagca tcttttctta
    96661 agttttctaa aaatctatca taaaatcctc caccatatcc taatctatag caatgtatat
    96721 catatgctac agctggtaca attacaacat ctaaggcctt aatatcaatt gtaggtgatt
    96781 tttcgttagg ttctcttatt ccatatgctc caattctcaa tccctctttt aaatctgtta
    96841 tttgagtagg gattaatgta tgattttctt ttattgtgat gggacttgat actattttct
    96901 ttagagacaa aagttttttg attaaattat ctgtttgaac ttcattgtta aaatttagat
    96961 aaagcattat attagttgca tttcttatat cttccatttg aagtaatttt tcagttatta
    97021 aatttgaatt actaagtaca aagtttgcat tcttattttt tcttgattca ataacttttt
    97081 ttctaaattc ttttttcata aaataattcc tcccttaata tgttataatg tgtacagcaa
    97141 ttgtatttaa tataaatttt agtataattt attgtaataa agcaatatat ttgggtaaat
    97201 gtaataaaaa taacagctag tcatataata ataatagttt atgtaaaagg agatgtatct
    97261 tgtgatttca aagaagaaag ctattttttt aggggtgatt ttagtaatta taacagctat
    97321 ggttacatca gcatttcagt tgacattggg gaataaagtt gtaatatcga aagaactcta
    97381 tgaagactat aaaaaatatg ataagttgtt aggactagaa tctattataa aacaagattt
    97441 ttataaaaaa gtatcagata ctgatttggt aaatggagca gcaaaaggtc tatttctagg
    97501 aacaaatgat aagtattctg gttattatac taaagatgaa atggagaatc taattaatga
    97561 tagtgaaggt tcttatgttg gtgtaggtat gtatataggg gcatcaaaag atggtggctt
    97621 agtagtagtt cccatgaaag attctccagc agagaaagcc ggtgtaaaat caggggataa
    97681 attagtaaaa gtcaatggaa aatctgtctc atataaaaat tcagatgaag ctgttcgtat
    97741 gatgaagggt aaaaaaggta aaacagttga actgactata ttaagagaag ataaacaatt
    97801 gaactttaaa gtaaaaacag accagataat tgagaagagt atagaaagta aagtaattga
    97861 taatgattta ggatatatag aaattaccca atttatatca agtacatata ctgactttga
    97921 taaagcttta aaagaattaa aagcaaaaaa tatcaaggga ttagtaatag accttagaaa
    97981 taatcctggt ggaatgctag atatatgtaa agaagttgct gatgagttaa ttggtgaagg
    98041 aactatagta tatacaaaag ataataaggg aaatactgag tacttgaaat ctgataaaga
    98101 aaaattggga cttccaatag tagtgttaac taatggagaa agtgcttctg ctgctgaaat
    98161 attaacagct gcaatcgttg ataataaaga aggtatttct gtagggacta caacttttgg
    98221 taaagggttg gtacaatcag ttgtaagatt gaaggatgga acaggataca agctaactac
    98281 tgctcaatat tttacaccta atggggatta tatcaatgaa aaaggtataa agcctactat
    98341 tgaagagaaa gatgaaaata aacagttaga tgtagcaact aagtggctta gagaacagat
    98401 tgataaatag gatttaattt ttataaactt atactataaa ataaagaaca ttataaaaga
    98461 gatgtctcaa aatgaacttt ttagttcatg agggagtctg gaaatattta tgtgtattct
    98521 ttaaataaaa atttattttt taagtgataa ttaaattttt acagacaggg ctatggtttt
    98581 aaaaatcata gccttatttt gatatttttt aaaaacatat tgcaacccag ttgttccaaa
    98641 tattatatca tttactttta aaatatcgca aactgcatat tatatattca ttataatata
    98701 atttatctaa ctagaacctc agtttactaa ttaaattaga tgcatagaat aactttttta
    98761 aacattgaaa ataaattaaa ctctaaacac atttaaatat aaatttatat atcattttga
    98821 cttggttaa
//
LOCUS       DAJMZY010000002        76554 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.002, whole genome shotgun sequence.
ACCESSION   DAJMZY010000002 DAJMZY010000000
VERSION     DAJMZY010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 76554)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 76554)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..76554
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.002"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            <1..1074
                     /locus_tag="OE968_000101"
     CDS             <1..1074
                     /locus_tag="OE968_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HCP7217418.1"
                     /translation="AKALKEELTEGEVYARLSSDYFAIFCDYKNGRNKIIRKLDNIRS
                     NIESNLSIVFEISLCVGIYFVEEGEVDIQKAVNKANMARSVAKGKNINYAIYNEDVRN
                     KLSEESMILDDIKIALVKNQFEVYYQPKFSLVTGEMIGSEALIRWNHPEHGFISPAVF
                     IPIAEKSKLILKIGRFVFERVCNDLYEWKKQGKKIVPVSVNLSRVELYQPDIVKFINK
                     TIKMYNLSSDFIEIEITETVAINELNILKNVLNELRTYGFSISMDDFGTGYSSISCLR
                     DMPIDILKLDKSFLGGIEHDERSRNIAKSIVSLAKSLDLVVIIEGVESKEQAELMKQF
                     GCDLVQGFYFARPMPAKNFLDLL"
     gene            1328..1990
                     /locus_tag="OE968_000102"
     CDS             1328..1990
                     /locus_tag="OE968_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-binding protein"
                     /protein_id="HCP7217419.1"
                     /translation="MIDISIDDKLKERWPNAKLGCIQAKVAVNKSSEKLINEINEFCD
                     TINQSLKVEDITKLDKIKDARNAYKELGKNPSRYRTSSEALVRRIIQGKGLYTINNIV
                     EINNLISIKSLYPVGTYNVSKLHSPVCFTVGDEGEQYKGIGKELINIENLPILSDSVG
                     KFGSPTSDSERAMITEDANEILICIFSFSQESDIEEYFGYAKELLKEYADGKDIETKI
                     IK"
     gene            2361..3770
                     /locus_tag="OE968_000103"
     CDS             2361..3770
                     /locus_tag="OE968_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase/peptidoglycan binding
                     protein"
                     /protein_id="HCP7217420.1"
                     /translation="MIDGKEVKQESGQKNLKFKIAIVVGVLFVAYIGMAIFFRNHFYF
                     GTTINGVKASGKTVEQVNDLLASSTNSYTLNLEERNNKKEQIKAKDIDLKFTPDDKVQ
                     KIKDSQSAIGWIGGIFKSKEYNNMITLSYNKDLLEKRFNALSCFDSKNVVEPKSAYPK
                     YDSTKNAYVIVPEVLGNKVKKDDFYKLVQNSINSGNTSISLDESKVYEAPNNTKDSEK
                     LKQAIKTLDKYVGVVVTYDFSDRKETLDGSEINKWLKVDSEKNYDITFDNDAMVEYTR
                     GLSKKYSTFGDSRPFKTATGKDITISGGIYGWLIDKKKEAEALVDVVKAGKNVTREPI
                     YIQKAVSRNKDDIGNTYVEISLSGQHMWFFKNGEMLVSTDVVTGDLARGFATPSGIYP
                     LNYKARNVSLTGQGYSSPVSYWLPFNGNIGIHDATWRNSFGGSIYKSSGSHGCVNTPF
                     SKAKKIYENIEPGTPIILY"
     gene            3885..4160
                     /locus_tag="OE968_000104"
     CDS             3885..4160
                     /locus_tag="OE968_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif11-like leader peptide family natural product
                     precursor"
                     /protein_id="HCP7217421.1"
                     /translation="MNEKLTKILEEAKNDDEFRKELIKTREQRDVMDSFCKVVTSRGY
                     DMTVGELFSMGEEYTSNLLKSVNGGAAYPIEDWSDWYEDFFIMLSNI"
     gene            4790..5101
                     /locus_tag="OE968_000105"
     CDS             4790..5101
                     /locus_tag="OE968_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7217422.1"
                     /translation="MAFEIIKSIVEAEQTADSIKVKAVTDAESIRADAVNKCESIFAD
                     VKKQAKLMEETLIEKAVTDSRAEVDKILANAKSECLKIEKTAEERKSKAIEAVIGKVV
                     R"
     gene            5103..7028
                     /locus_tag="OE968_000106"
     CDS             5103..7028
                     /locus_tag="OE968_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HCP7217423.1"
                     /translation="MAIVNMNKISIVGLEAQKSQILKLLMNRGFVQIDDSAFLTEEEE
                     LKNYLVKDSEESEVIMLEQKMSHVNQAINIVSSLVKQKKSLLAPKREFNKIDSEKEGQ
                     VYAEALELNNLHKEIGTIRSNINLLNNNKSMLEPWVNFDIPIENMETKYTKTILGTVP
                     ISANIDALRVKLEDEIPESVIGIVNSDKLMNYVYLITLKETFDDVLEVLKEFNFSVVS
                     LPNEEGTPLQAIKKYNEMIIRQENVSKDKTEEIKRHADSIHMLENLYDFYTIERDQKK
                     IIERLVKTKTTFCLNGWLPSKRADELIKEITEKFDCCVQTEEGSKEEGFPILLENNKL
                     VTPFESVTNMYSYPSTKDIDPNTILTFFFVIFFGMMLSDAAYGLIIAVVCGFVVYKLK
                     IQKGEGNLIKLIGICGVSTTVWGLIFGGILGDLIPIKALINPLEDVMTLMGMSLLFGI
                     IHIYVGLGIKAYTLIRSGKVIDAIFDIGFWYLCITGVCLLIIPFVAGDIGVFSEVGKY
                     LAIIGAIGLVLTQGRSFKGIPVKLFKGFSSLYGITSYFADILSYTRIMALCLTTGVIA
                     QVINLLGAIAGPILAVVIGVVGHTINLLINALGAYVHTSRLQYVEFFNKFYEGGGVPF
                     VPFKYKTKYTSINKKEM"
     gene            7031..7522
                     /locus_tag="OE968_000107"
     CDS             7031..7522
                     /locus_tag="OE968_000107"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HCP7217424.1"
                     /translation="MEFLNALGNGQFLAISGAAIAALFAGMGSAKGTSIAGQAAAGVV
                     TEDPSKFGQLLVLQLLPGTQGLYGFIIAFLILSKAGIIGGDAIPTSAQGLQLLMAGLP
                     IGLVGLVSGIAQGKAAAAGVGIVAKRPEELGKAITFAAIVETYALLGLLVSFLAYNGI
                     AIG"
     gene            7574..8137
                     /locus_tag="OE968_000108"
     CDS             7574..8137
                     /locus_tag="OE968_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit E"
                     /protein_id="HCP7217425.1"
                     /translation="MGNEQKMIDRIIADAKQEAQEILDKAKSEADLKVNSANEKAEKE
                     MASYTKLAEAEAEKAASKEISGAYMEAKKQILSKKQEILEEVILEAKNKLLNLKDNEY
                     EEIILNMIEKSNCTDDSEIVLSKKDKKTLKDVLSKKGIKVSDETRDITGGFIVKKGDI
                     EYNYSFEAIIAVEHEYIEQIAAEILFN"
     gene            8152..9129
                     /locus_tag="OE968_000109"
     CDS             8152..9129
                     /locus_tag="OE968_000109"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit C"
                     /protein_id="HCP7217426.1"
                     /translation="MAEEKTYPYAVARIRVLEKQLLNRQMFIQMAEAKSPEDSLRIIA
                     EAGYADTSNNNIHNFENILTQELSKTYEILKSLAPEEKFVDVFLYKNDYHNLKVLIKE
                     EISGVDGEKYLIDGGTIPLIKLRESLANRSFSDLPKIMSSAILEAFDVYNKTQNGQMV
                     DIVLDKATFTSMKETAKESQNKFVIDYVMKVCDLTNLKSFIRVKNMKKDFDMFMNVFV
                     SGGSLDKEKFLEAFSSDTPASCFKSTSYSDVCKNGMDSGFTVFEKLCDDYLMEYVRGA
                     KFKPLTLEPLIAYLYAKESEIKTIRIILTSKLNNIDADTIKERLRDAYV"
     gene            9116..9439
                     /locus_tag="OE968_000110"
     CDS             9116..9439
                     /locus_tag="OE968_000110"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HCP7217427.1"
                     /translation="MLMYKVGVVGDKDSIMGFLALGIDIFPAYDSDEIKKSIHKLVED
                     EYAIIYITEQASLLAKESIAKYKDYQLPAIIVIPGIGGSMGLGMNEVRESSKRAIGAD
                     ILFKE"
     gene            9556..11334
                     /locus_tag="OE968_000111"
     CDS             9556..11334
                     /locus_tag="OE968_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HCP7217428.1"
                     /translation="MKTGTIVKVSGPLVVAEGMRDANMFDVVRVSDKHLIGEIIEMHG
                     DKASIQVYEETSGLGPGEEVVSLGMPMSVELGPGLISTIYDGIQRPLEKMYDISGTNI
                     TKGVEVSSLDRTTKWEFKPKKSVGDKVVAGDIIGGVQETAVVECKIMVPYGVKGTIKE
                     IYSGEFTVEDTVCVITDEKGNDIPVTMMQKWPVRKERPYREKKTPDSLLVTGQRVIDT
                     FFPITKGGVAAIPGPFGSGKTVTQHQLAKWADADIVVYIGCGERGNEMTDVLLEFPEL
                     KDPRTGESLMQRTVLIANTSDMPVAAREASIYTGITIAEYFRDMGYSVALMADSTSRW
                     AEALREMSGRLEEMPGEEGYPAYLGSRLAQFYERAGKVNCLGMDEREGTLTAIGAVSP
                     PGGDTSEPVSQATLRIVKVFWGLDASLAYKRHFPAINWLTSYSLYQEKVDVWADKNVN
                     DNFSAQRAQAMKLLQVESELQEIVQLVGVDSLSDGDRLILEVTRSIREDFLHQNSFHE
                     VDTYTSLHKQYRMMGLILKFYKSAQDAIKQNVTINDIIKLSVLEKIGRAKYVEEGDID
                     AAYDSIEDEIDNELADLIKKRGAEEL"
     gene            11331..12704
                     /locus_tag="OE968_000112"
     CDS             11331..12704
                     /locus_tag="OE968_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HCP7217429.1"
                     /translation="MIKEYKSIQEVAGPLMLINGVEGVKFDELGEIELSNGEIRRCKV
                     LEVNGDTALVQLFESSTGINLAESKVRFLGKSLDFGVSPDILGRVFSGMGRPIDGGPE
                     IIPDKRLDINGAPINPAARDYPAEFIQTGVSAIDGLNTLVRGQKLPIFSGSGLPHANL
                     AVQIARQAKVRGTDSKFAVVFAAVGITFEDAEFFISDFKATGAIDRSVVFVNLANDPA
                     VERVSTPRMALTAAEYLAFEQDMHVLVIITDITNYAEALREVSAAKKEVPGRRGYPGY
                     LYTDLATMYERAGKMKGHEGSITMIPILTMPEDDKTHPIPDLTGYITEGQIILSRELY
                     KKDIQPPIDVLPSLSRLKDKGIGKGKTREDHADTMNQLFAAYSRGKDAKELMAILGES
                     ALSEIDLMYAKFADEFEKEYVSQGFRTDRTIEQTLEIGWKLLSMLPKSELKRIRDEYF
                     EKYMPKE"
     gene            12710..13378
                     /locus_tag="OE968_000113"
     CDS             12710..13378
                     /locus_tag="OE968_000113"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HCP7217430.1"
                     /translation="MARLNINPTRMEMTRLKKLLKTATRGHKLLKDKLDELMKQFLEI
                     VRENKRLREEAENALDTAYKNFIIARAVMSQEYLGSALMMPKQSVSVDVSTRNIMSVD
                     VPVFDFKTENNQSDIYPYGLAFTSGELDSAMEAFSDAMQPLLRLAESEKSAQLLAQEI
                     EKTRRRVNALENVMIPNYIETIKYIAMKLEENERASTTRLMKVKDMVLKKALEEKKKN
                     DLVV"
     gene            13655..14704
                     /locus_tag="OE968_000114"
     CDS             13655..14704
                     /locus_tag="OE968_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="HCP7217431.1"
                     /translation="MKEFIFTCLCIVVITFMTSCISTTPQTTQGKGNNKLTIYAALEE
                     EQIAYYMEGFREEYPNIDVEIVMDSHGVIASKLLAEKDNPQADIIWGLSAMNMIELKK
                     DGALEAYKPKNYDKVDKKFKDTEDDVSWVGMSVPETAIVVNYKELKKLGIDIPKSYED
                     LIKPEYKGLITMPNPASSGTGYLTVSGLIQMMGEKDAYNYMDKLHKNIATYTHSGSKP
                     AKLAGSGEYPIGITLGYRATQQLSSGEPIEVVFPKEGSGWDLEANALVKKDNIKKEAK
                     LFLDWAISDSAMDRYAHEVAVTSIKTDNPVPKGYSKQPFEQLIKEVDLNSAAKNRSTV
                     LKTWESKYGSKSESK"
     gene            14800..15789
                     /locus_tag="OE968_000115"
     CDS             14800..15789
                     /locus_tag="OE968_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCP7217432.1"
                     /translation="MSYLKINNVFKSYDQKKVLNNISLDIEEGEFLCLLGPSGCGKTT
                     LLRIIAGLEDVNSGTIILQDKDITNLEPSKRGFGIVFQSYALFPNMTAYNNIAFPLKE
                     RKVSKEKIDNKVKEVLETVGLTNEAHKYPKALSGGQQQRIAIARALALEPKFLLLDEP
                     MSALDAKVRHKLRMDIKRLQKELNITTIMVTHDQEEAITMADKIAILNGGDIMQIGTP
                     EEIYQNPQNLFTAQFIGDTNCFDNGDSILTVRPEYVQIEKSTKENYQGIISNIEFRGN
                     LLRVEIKDKLNENFIISDVSIKEWVNLNLVEGDLVKISIDEKYYLKYPKVKGA"
     gene            15794..17512
                     /locus_tag="OE968_000116"
     CDS             15794..17512
                     /locus_tag="OE968_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     permease subunit"
                     /protein_id="HCP7217433.1"
                     /translation="MNNNAISSKSISLKSKMNLDIKKCMLTVLVMSLVIFLLAPIIYL
                     FVQAFLDKDGVFVGLQNFQEYLASESLLNSLKNTVFVSVISTVISLTLALVYAYALTR
                     TKIKFKGFFKSLAMFPMFAPTMMHAIGLVYLFGNQGLVTNLLGVHVPIYGAVGIILAQ
                     IIYVFPQSFQILYISLSSTDYRLYEASNTMGISKIREFISITIPSIKYSLISSAFVSF
                     TLCFTDFGAPKVIGGEFNVLSIDVYKQIIGQQNMPMGATVSILLLIPAIISFIVTKKI
                     EKNQNSYITSKSIPYKVKTNKLRDSILGGVVGIIAFGIIAVMLTVILSSLISVWPYDL
                     RLTLEHFSMKNSIDGIKPFINSIKMSLFTAILGTSFVFLFAYLNEKTEKAPYLKSFGY
                     FLSTLPMALPGLVLGIAYVLFFNKLEFNFMDTIYIKNLFNGLYGTLLIMVICNIVHFF
                     SVAFITATTAIKKVDKELDMVAKSMGINSASILKNVTIPLCLPAVLENFMYFFLNSMV
                     TISALVFIYTASSKVAAISIVQLDDKGSTAQAAALAVLILVTNILVKVIYEFIKNRLE
                     KRTNFN"
     gene            complement(17594..18748)
                     /locus_tag="OE968_000117"
     CDS             complement(17594..18748)
                     /locus_tag="OE968_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HCP7217434.1"
                     /translation="MKINKKFNRVDMQVSILTAIIVIISSSCVYFFNYTLTYKSMIYS
                     LSERSKHIYEYVERNIDKNTFTEINSKEDQSKKSYKSSKILLESVKNTTGVMYLYTAK
                     KTKDGSLVYVVDGLNSSRSDFRNAGDLIEKEIWGDLNKALDNHILLPKKIKSTSWGYI
                     FISYFPIHNDVGKVVGVIGIEFEAKHQYNTFKFISIVTPIIALLTCLISALIAVILFK
                     RISNPTYTDFANTDYLTGLKNRNAFEIDMNNLNNSNLKNLISIISIDLDGLKKINDKF
                     GHQTGDLYIKQASKIIQYVINKKYIVYRIGGDEYIIILKNLSHKEINNIINNINLKIV
                     EENSTNELKLSMSIGYAIFDEKVDVSLFDTYRRADSQMYDNKRKINKQYQ"
     gene            19247..20608
                     /locus_tag="OE968_000118"
     CDS             19247..20608
                     /locus_tag="OE968_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HCP7217435.1"
                     /translation="MKDRLNLTEGRITEKLLKLSLPIMGTSFIQMGYNMIDMIWVGKA
                     GSKAVAAVGTAGFFPWLAMAFIMISKVGGEIKVAQSIGANNISTTKSYMKSAIEINII
                     LAIIYTISLIVLNKQLIGFFRLGDLEVITMSRQYLIIVALGMVFYFINPVFTAIFNGL
                     GNSKTPFRINTVGLITNIILDPILIFGWGFAPKLGVAGAAIATVFAQIVVTTCFIYII
                     VKSKEEYFKLRLFKEIETKYYKVLYKLGLPIAIQSGMFTVFSMLLGVIVASWGPVAVA
                     VQKVGSQIEAISWMTAEGLSVALGSFVGQNYGAKKYSRINKGCKIAITVSSVLGIITT
                     LVLVFAGESIFSIFIDESEAIEKGAVYLKILGYSQFFMCLEIITTGAFKGLGRTYIPS
                     IIITILTGARVPLAYFISRPEMLGLNGVWWSITLSSILKGILMISLFISLLKLGKLYK
                     ISE"
     gene            20699..21403
                     /locus_tag="OE968_000119"
     CDS             20699..21403
                     /locus_tag="OE968_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCP7217436.1"
                     /translation="MKEPIYKVIENHVRELINSDSLKEGDLIPSEKQLSEEFNVTRMT
                     VRSALNNLVKEGYITRQRGVGSIVIANNIYDNISSVSGFTKEMESKGYKVSNILVSLE
                     IVQADENLSSKLNISLEENVWEIKRVRLANDARVSYMITYMPVKLFPNLNKTHCENSL
                     YNFVEEVCEYKIAMSEREVQAVISNEECMDNLKLEEPEPLLYISQICKLQNSEIFEYS
                     HTYHYGYTLTLNAVVE"
     gene            21603..21914
                     /locus_tag="OE968_000120"
     CDS             21603..21914
                     /locus_tag="OE968_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCP7217437.1"
                     /translation="MIKIMLACSAGMSTSLLVTKMEDAAKENGIEAKIWAISEVNLKN
                     EIENCDVLLLGPQVRYVLGKATEMAKPYNIPVEVINMMDYGRCNGKAVLDRAVELNSS
                     K"
     gene            21936..23249
                     /locus_tag="OE968_000121"
     CDS             21936..23249
                     /locus_tag="OE968_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCP7217438.1"
                     /translation="MEKFMSFMDKYIVPVAAKIGAQRHLVAVRDAFIVMIPITMVGAL
                     GTLINNLPLEAYKNLMASIFGENWTTFGGDLWWGAIGTMAVFLVIGVAYFLAKSYESD
                     GLQSGLIALSIFFIMAPQIGKIVPEGGTTVVEGWGMIQQTYLGTAALFSSILIGLLST
                     EIFVRLSKVKKLTIKMPDGVPPAVSRSFAKLIPGMLTIMIFTVIGIFIKMLSNGSFLT
                     DILNTYLGAPLSNVADSLGSTMLIAFIIHILWTVGLHGANIALPFTETILMKLGGENA
                     ALAQAGATEGYHVLAGAFFDAFVYLGGSGMVLGLIVALLIAGRRRKEMIVLGGPPAIF
                     NIGEPLIFGLPIVLNPIFMIPFVLAPVICSAVSYLAIDFGLVAPVILPKIPWVTPPIL
                     GGAMATGDWTGGALALFNLILSILIYIPFVIASEKMEANKLKINN"
     gene            23346..24656
                     /locus_tag="OE968_000122"
     CDS             23346..24656
                     /locus_tag="OE968_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HCP7217439.1"
                     /translation="MKKGLKIVTIGGGSSYTPELVEGFINRYEELPVKELWLVDIEAG
                     KEKLEIVGNLAKRMVKKAGVDMKINLTLDRREALRDADFVTTQLRVGLLDARIKDETI
                     PLSHGVMGQETNGAGGLFKALRTIPVIFDIIKDVEELCPNAWMVNFTNPTGIITEAVF
                     KYTNFRRYIGLCNVPIHLKNDVAKLFNVESDRISMDFAGLNHMVYGLNVSLDGEDVTK
                     EAIDKFVKADISMQNIKAIDFNAEFVKSLGAIPCPYHRYYYKTKEMLEDELREFKEGK
                     ARGQVVKELEEQLFELYKDEKLDVKPPQLEKRGGAYYSDAACNLISSIYNDKKDIQVV
                     NTLNKGSIRDFKDEQAVEVSSVITKNGPKPISIGYLPDSVHGLVSQIKSFEVLAAKAA
                     VYGDYESALLALCINPLIPSDDLAKTILDEMLEAHKDYLPRFNR"
     gene            24682..25413
                     /gene="chbG"
                     /locus_tag="OE968_000123"
     CDS             24682..25413
                     /gene="chbG"
                     /locus_tag="OE968_000123"
                     /EC_number="3.5.1.105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chitin disaccharide deacetylase"
                     /protein_id="HCP7217440.1"
                     /translation="MTKIIINADDFGYCEAVNYGIISAHNNGIVRSTSMMANMPGVEH
                     GVGLLKENKTLNCGVHMTLSCGRPLLSNLKTIVDKDGFFIRRITDEIIEKMDCDEIYR
                     ELCAQIDRVKGLGIDISHLDSHHHIHTLVSLKPVIEKIVTKYNLPIRGGFEYNLEYSK
                     VVPLIDSFYKENVSEEYFIKNIDEIMKYDVVDIMSHPAFLDDYILNSTSYAIDRTKEH
                     KILTSKKVKEFLEKNGLVISSYRDI"
     gene            25426..25743
                     /locus_tag="OE968_000124"
     CDS             25426..25743
                     /locus_tag="OE968_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HCP7217441.1"
                     /translation="MDEKMIEISFGIIGFAGDAKGLAFEAIKEAKSGNIDKARECIEK
                     SKESIHKAHKFQTELIQNEANGNKTEISVILIHAQDHLMTAMNFQQLAEEFIDVYERL
                     ESK"
     gene            complement(25855..26319)
                     /locus_tag="OE968_000125"
     CDS             complement(25855..26319)
                     /locus_tag="OE968_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016208838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7217442.1"
                     /translation="MVHLVYCDNAGKKGEKVLDKILDGTKTMVIRGAAGRKIPHSRVF
                     EDELLYFMEKGTAKISAKATVKKVENYVKLTEDEISKILNENQPKLNLSEKQKVRWHK
                     KCLCLVEFENVEEITPLDFDHQGNMDDWLIVEKIEDVVVGTSIPYNYEKSKF"
     gene            26589..27527
                     /locus_tag="OE968_000126"
     CDS             26589..27527
                     /locus_tag="OE968_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HCP7217443.1"
                     /translation="MKKIKSLAIFISIITTLVLVTACSDKNTEDKDKSETRVVQSVKG
                     EVKIPSNPKKIVDISGSSEELLLAGYKPVATANVDSYETDKLPSYIREELKGVKIVGH
                     SMMDTMDMEAILEVNPDLIIMSQRQEKIYDQLKEIAPVVMMKDYANDWRSKLTDVSKL
                     FDKEEEDKSWLQKYDEKATKLGKEVIEKNGEKTYLPVLASSGQFMVFSDGGIGTLIND
                     DMKLARPKNMPKQDGITLPMVSMEGLTDIDADHIVVIATEADKKDLENSAIWAQIRAV
                     KDGNVTILDAAPFFSQSYNPIGKELLLESVKNELTK"
     gene            27655..28668
                     /locus_tag="OE968_000127"
     CDS             27655..28668
                     /locus_tag="OE968_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HCP7217444.1"
                     /translation="MTKLSKKNITYLLILVSIVVLVFGIVLSITIGAKDMNLSTVIDS
                     LIKMEDGINMRIVKDVRLPRAIAAALVGGFLAVSGAIMQGITRNPIAEPSVIGITQGA
                     TFAISISLVLQKKLPQLIHGSFSVMMFAFIGASISGLFIYFISSKSRGRVNNVKLALA
                     GVALGTLLISLASAISMYFNLSQQLSFWISGGLVGVKWEGIKLLFVAGGIGFILAIIM
                     APRITILSLGEEVAIGLGQKTKFVRFICIVLVILMTGASVSVSGNIIFIGLIVPQIAK
                     GIVGSDYKYIIPSSLVLGAVLLVYTDILSRMINPPYETPVGSITALIGVPIFIYLVRK
                     GEK"
     gene            28674..29696
                     /locus_tag="OE968_000128"
     CDS             28674..29696
                     /locus_tag="OE968_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HCP7217445.1"
                     /translation="MKNIIKINSKTLLVISILMVLIFITFLLSLNMGSFSIEPMDVIK
                     TFLGQGQRNHEIAIFKLRLPRIVIALLVGSALSTAGVILQGVTKNDLADSGILGINSG
                     AALFVVVYIYLMNGNVYEGMSNLTVFTMPIVALIGALFGAFLIYSLAWKGGINSSRLL
                     LIGIGVNIAFTSILTIFQLKFTTQEFNRVMAWTSGSIWGTSWKYVIAVLPFIVIFMGI
                     TIYKSKYIDVLNLGDEVSISLGVDVEKQRRRLIIYAVILSGVSTAVAGSISFLGLIAP
                     HIGRKIIGPKHKRLIPVSALIGTLLLLIADTISRNLLAPIEIPVGIVVSIIGVPYFIY
                     LMLVND"
     gene            29711..30493
                     /locus_tag="OE968_000129"
     CDS             29711..30493
                     /locus_tag="OE968_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004460318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCP7217446.1"
                     /translation="MNCINTKNLNVSYGNTDIIKNLNLNIPKGKITTIIGANGCGKST
                     ILKTIGRIISPNSGKIYINGEDIYKKKSKEIAKDMAVLPQSPQAPSGLTVSELISYGR
                     FPHKSGFGNSSKEDREIVNWSLEVTGIAEFKDRNMEDLSGGQRQRAWIAMALAQETDI
                     LLLDEPTTYLDLAHQLEILKLLDELNKKQGRTIVMVIHELNNAARFADHMIGIKKGKI
                     VCEGDAYDVMTKDNLKELFNIDAEIATDPRTNKPICITYDMV"
     gene            30505..31845
                     /locus_tag="OE968_000130"
     CDS             30505..31845
                     /locus_tag="OE968_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HCP7217447.1"
                     /translation="MENQEALRHEKIWILLFRYSIPAIIAMMVTSLYNVVDRAFIGSM
                     EGIGSIAIAGLGVTMPVFTLIIAFGMLVSVGASTRLSIKLGERNREEAEKILGNALTL
                     SIIISLIITILGLVFLEEILFILGASKDSIFYAKDYMSVILVGSIFNLVAFSLNNAIR
                     AEGNPKLAARTMIVGCVLNLILDPIFIFVFNLGIKGAAIATVLCQIVVFFWVIHYFIR
                     GKSNLKLKKCNLKLNKDIVKKVFAIGMTPFAMEVAISITHMFTNNSLKVYGGDLAIGA
                     MTALTSILLMFMMPVFGLNQGMQTIISYNYGAKQYERAKKTLILSIIVSVVILSFGFL
                     VVQVFPEVFVGIFNKDSDLMDIAVRGISLNLITLPIMGISIVGPVYFQCISKVKHSMF
                     LTLLRQFILFIPLIIVLPIQFNLDGVWLAQPVADFIAMIIVLLFLKREFKTSRV"
     gene            complement(31940..34219)
                     /locus_tag="OE968_000131"
     CDS             complement(31940..34219)
                     /locus_tag="OE968_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HCP7217448.1"
                     /translation="MNFENTKNKKIIATLLLTLLLIVSLTCVTFIMNLNKVTHNETER
                     YLVEVSQGISTTINVKCKSIFRTLYSMGDTYFEINDSEKEVNRYLSKKLKLFEFDWLG
                     IIDSNGNFVSALKDTGNVKGQDFYRKALQGKETITPVKSQSGTYGILYSVPLYNGDKI
                     VGAVAAWNTIDTMRNLLSVESFHGEGFSQIIDQDGNFIVSSANKNAPKNVVNFFDMIK
                     HQGKQVDKNKLEEMKINLKKNKTGSMYYTLNDGISKAMHYLPLQEENLYLLSIVPTKT
                     ASAQFDLLLKKAIFINILIVILFLLLIILIMFINQKNRAQLIKIAYVDSVTKGYSKAR
                     FDIEAKKIIQSSSSESYSLVSINIQKFKLINDSFGSEAGDKTLKYIHDVISNYLEPGE
                     LLCRVSNDQFNVLIKTIPQKEILKYIENITNDINSFNKNEECKYFIALSIGVYKIDDP
                     NLPLVSIQDRANVARKNNKGNIGNHPLYTCVFYSDLERLKMIKEKEMENRMEEALNNN
                     EFIVYLQPKISLKDNTIVGAEALVRWQDPNKGLIPPDEFIPFFEKNGFITKLDHYVFE
                     KVCSMIRKWIDNGETPIPVSVNFSRANLNNIDFLEKYRMLRNKYNIPAKLLEIELTET
                     LVFENLQKLINIIDQIHEEGFQCSLDDFGSGYSSLNMLKEIKVDTLKLDRAFFSSPNA
                     DNIAENHVIESIVNLAKKLNMNSISEGVETILQMDYLKKINCDMIQGYVFSKPLPQEI
                     FEKMTFGKKLEETSMDSSV"
     gene            complement(34556..35719)
                     /locus_tag="OE968_000132"
     CDS             complement(34556..35719)
                     /locus_tag="OE968_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HCP7217449.1"
                     /translation="MKLMGYLRENGQFGIRNHVLIIPTSVCSSETATRIASLVPGAIA
                     IPHQHGCCQIGSDIELTAKTLIGFGKNPNVAAVLVVGLGCDGIQAKELASEIATTGKK
                     VDYVVIQECGGTLKTVSKGAEIVSKMAREVSKEVRVEFGMSEITLALECGGSDPTSGI
                     ASNPSIGVASNLLVDEGGSSILSETTEVIGAEHLLATRFEDEEMKDKFLKFVSDVEKR
                     AIAMGEDLRSGQPTPGNKTGGLSTIEEKSLGCMYKAGNKPFKGALEYADIVPPDKKGL
                     YFMDTPGQDIDSITGMVAGGAQIVIFSTGRGTPTGSPISPVIKITGNSDTYNKMPDNI
                     DINAGRIITDGAKIADIGQEIFNEIIEVCNGKHTKAESLGHREFGIYRISSTF"
     gene            complement(35732..36007)
                     /locus_tag="OE968_000133"
     CDS             complement(35732..36007)
                     /locus_tag="OE968_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HCP7217450.1"
                     /translation="MNAIIHANEKDNLVTCVRPLVKGEKVSIDGKSYIVNDNIPVFHK
                     MATEDVKKGDVVYKYGEIIGIATVDIKTGDYVHVHNIESTRGRGDKK"
     gene            complement(36028..37002)
                     /locus_tag="OE968_000134"
     CDS             complement(36028..37002)
                     /locus_tag="OE968_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-keto-3-deoxygluconate permease"
                     /protein_id="HCP7217451.1"
                     /translation="MHILKSVKKIPGGLMVCPLLLGALFNTVCPQALEIGGFTTSLFK
                     TGAMSILALFCLCNGAQINIRQAGKPLTKGIVLTATKFIIGAVLGIIVSKFIGPKGII
                     GITPLAIVATMTNSNGGLFAALAGEYGDSTDVGAISILSLNDGPFFTMLAFGVTGLAN
                     VPIIALFAALIPILLGFILGNLDEDIREFLAPGTTLLIPFFAFPLGAALNFNQIITAG
                     LPGVVLGLGVTIITGMGGYFVMKLIRAEHPAVGAATGTTAGNAAGTPEALAAIDPTLA
                     TIAAVSTVQVAAAIIVTAICCPMLVSYLDKREKKKKSIFKTNKNIEVN"
     gene            complement(37273..39186)
                     /locus_tag="OE968_000135"
     CDS             complement(37273..39186)
                     /locus_tag="OE968_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HCP7217452.1"
                     /translation="MKYGGIIMKEILVIAPTKGTYEKSIHIVKKNKYTNIDVVFGNLK
                     EGIPLAEKSINHGTRIIISRGGTYNMLKATYNIPIVEIKVDAYDIIKSYKEVKNSNEP
                     FGIIGFNNVIYGFDIIEEILNKKITMIEIEKEEEIYDAIEKYRKKGINTYIGDTTVAH
                     IVKRLNCKGILIESREENILRAIQQAEQILEATKDEQKRRLQIEAMTDFVHDGIITVD
                     KNFKITLFNKSAEKIFGIKKENALYHNVVDVIPNTVLPQVVETMEPQIGEIQNIGSTK
                     IITNRVPIIVDGQIQGAVSTFQDSKEISSFEHTIRRSLLSKGLSAKYTFDDIIHASEK
                     TKDCIELAKKYACYDTPMIITGESGVGKELFCQSIHNYSKRKNAPFVAVNCAAIPPSL
                     IESEFFGYEEGSFTGARKKGKAGVFELAHEGTIFLDEISEIPLELQGRLLRVLQEKQV
                     MRIGGDKVIPIDVKIICASNKDLKNMMRNGLFRQDLYFRINILTLYLPSLKERKEDII
                     KLSEFFIHKYSSKYNKTPLIITPNIKKALLEREYEGNIRELEGMMERAVIVESFDSIL
                     LEKVSNEYTNNIVDKDNSDFECSNLDLKTLEKKYIYKIYNENNRNTTKTCEILKITRS
                     TLWRKLKEIEDDV"
     gene            complement(39363..40577)
                     /locus_tag="OE968_000136"
     CDS             complement(39363..40577)
                     /locus_tag="OE968_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HCP7217453.1"
                     /translation="MNQEYVKGNPIFTNINKVPRQFPYLTDDIDTDVIIVGGGVTGCI
                     CAYYLAKNNIKSVILEKGRIAHGSTSVTTSLLQYELDDNLIDLTEVMTLKDALKAYNL
                     CTSALEELDTFIELYGNKCDYAKRDTLLYTANKLEVKAIKEEYNLRKENGFDVEYIDE
                     STNPFNFDLKSGLIAKNGGRELDPYKYSHHLIDVSLKNGLQVYENTEVKKVDLSNDKV
                     TAEVSYGYKVHGKKLIVATGYNTSLFTKRNFATKSNTFNIATKPLKNIASWKNNILIR
                     DNCDPYNYLRTTKDNRLIIGGEDVSFDDIENETLANEKYDILEQRLKSMFKDIKDIEV
                     EYKYCGCFASTLDNLGFIGPDNKNNNLWYCLGYGANGILFAILGGIMLSELYLGKQNK
                     NMKLFKVDRFDK"
     gene            40821..42203
                     /locus_tag="OE968_000137"
     CDS             40821..42203
                     /locus_tag="OE968_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011967718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TldD/PmbA family protein"
                     /protein_id="HCP7217454.1"
                     /translation="MLSKNIASKVLEKCLITGGDFAEIFEEDTINNSISLIDNKVENA
                     IGGRNYGIGIRIFKGLKSIYAYTSDNSLNSLLDVAYKAAVALGKLEDGKSVILNDSIK
                     INNIHNIKIYPNSIGNKDKVSVMKVAYKSAKEFSNDISQVSVSYLDKDQKILIANTEG
                     IYVEDRRIRTRLGISSIASKGNENQTGFEGPGGCKGFEIFEEIDPEYYAKESARVAHT
                     MLHAKNCPAGNMMVAIDNGFGGVIFHEACGHSLEATSVAKGNSVFADKLGQQIASTKI
                     TAIDDGTIPNYWGSMNIDDEGNPTQKNILIENGILKSYMIDKLNGRRMGMNPTGSSRR
                     QNYKFAPTSRMTNTYIAAGEDRPEDIIKSIPDGLYAKKMGGGSVNPVTGEFNFAVSEG
                     YLIKNGEIQEPVRGASLIGKGSDILMNIDMVGNNVKQAQGMCGSSSGSIPTNVGQPMI
                     RVKEITVGGR"
     gene            42215..43564
                     /locus_tag="OE968_000138"
     CDS             42215..43564
                     /locus_tag="OE968_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TldD/PmbA family protein"
                     /protein_id="HCP7217455.1"
                     /translation="MELKNFKDILFKKALSEGFEEYEIYYYTGENLSINIYEGEVEKY
                     NLDKSFGLSFRGKVNGKIGYSYTEILDDKAVDMLIKNVKDGVNTIENEDVQFIYEGDK
                     HYNDVKTYSKELENLEADKLIDLALEMERETKAYSDKVVNLSKCTISYSVSSNGISNT
                     KGLNLSNKTNMLIGFVVPIIEDNGQKYDGIGYNIANSIEEIKPCEIAKLGVDNALSKV
                     GGKSIPSGKYKTILLNEAMVSLLSTFSGIFNADSAQKGLSLLKNREGDMIASPIVTIV
                     DDPLLENGMASTPFDDEGVATFKKEVVLNGKLITLLHNLKTANKAGVKTTGNGIKSSY
                     SSPISIYPTNFYIEKGDKSLDEIIKDIDEGLMVTSFAGLHSGANSVTGDFSLAAKGFY
                     IKEGKKVFPVEQITVAGNYFDLLKDIEAIGEDLEFPMSSIGSPSVVIKELSVAGKDE"
     gene            43714..44247
                     /locus_tag="OE968_000139"
     CDS             43714..44247
                     /locus_tag="OE968_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HCP7217456.1"
                     /translation="MSDAHYDMHKRNGYSSDEPYPEIKVLGPNKYYAELLMDDYAGVS
                     SEFTSVNQYLYHNFDLDETHRELSEMWINISITEMLHMEILAKTIRLLGGNPVYRGST
                     SSCGAYWNGGFVCYGNSICNRLKLDLHLEHVAINNYYKDISLIEDPYIKAILNRIILD
                     EKLHVSLFEKAIEKYCK"
     gene            44331..45140
                     /locus_tag="OE968_000140"
     CDS             44331..45140
                     /locus_tag="OE968_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HCP7217457.1"
                     /translation="MYYVYVNDINIAVYDLNPSAKKTVLFIHGWPLGHKIFEYQTNIL
                     PKLGYRTVSIDLRGFGKSDATSGGYTYSQLADDIYKVVHAIGLKDFTLVGFSMGGAIV
                     LRYMSLFNGYGVSKLVLAAAAAPSFVQRPPEFPYGMTREDVNKLIAQACTDRPEMVTD
                     FGEKVFASNPPESFRRWFNDIGFSASGIGTIGTAVSLRDEELFNDLKCVRVPTGIFHG
                     KLDEICPYEFAVFMNEKIEDSILYTFEYSGHAIFYDELKLFNQKFLQFLEE"
     gene            45551..47596
                     /locus_tag="OE968_000141"
     CDS             45551..47596
                     /locus_tag="OE968_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HCP7217458.1"
                     /translation="MKKHNILFVSTDDKINIDISKQLENIFGEFCNIDNLVYVNRINI
                     ELSSYELVVCSDNDIKEYIHNNIDKNIPIVIVHRTINIENINQIISIENDSDVMVIDA
                     YKESADETAKIIRKLGLIHINLIPYYPGCDKSKCEIGIITGSRNSIPQNIKQIIDIGD
                     KVIDINTVIEIFTKLNISIDKLHIIKEKYNEDTVSGYRYYTTMNKTMKSFLEIIDEGI
                     ASVDKLGKFIYCNKVFSNLVGIDQNEIISNNFMDLFSDKVVKKIFFQEDEVNDEVVNL
                     NNKKLIINKVNVYENNERIKSIISIKNISAIQVLEDKIQNKLQSKGFVSKYTFESVVG
                     ESKIIKEKINIARKIATTDFSVLILGENGTGKEIFAQAIHNESLRKNKPFVAVNLSSL
                     SDTLIESELFGYDEGSFTGAIKGGKMGIFERAHTGTIFLDEIGDISLDVQQRLLRVLQ
                     EKEVMRMGGSKIIPIDVRIIAATNKDLKKKIKEGSFREDLYYRINVLHIEIPRLRERK
                     EDIPLISKYFLDEINSNKCFTEESMQALTLYEWPGNVRELKNLIYYIDTIVEEDRVDY
                     EHLPEQFRFEKNNTLVNENFDSIILDFKQSNFFEESICILTSIETWNNKNILLGRNKL
                     QEILKEKDIVLSVDQIRKRIDKLKSHGLLLSGVKKQGSFITDEGKNFISYVKIKGVI"
     gene            47857..49056
                     /locus_tag="OE968_000142"
     CDS             47857..49056
                     /locus_tag="OE968_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HCP7217459.1"
                     /translation="MKSAYKGYEAYSYLEKGKDISSIEMCKGDKRVKEYLIELDDIQE
                     AKVKSIVDEKIFISLHEHPVLFPEHLERDIFEYNREGKQRCAYEALSRGYYDAIFDNL
                     MDGVCTITSNSGWKWDDILIDLGMRLCDLAHQDFVIKCEKVEDIYRAKSEGKVALIPT
                     LEGAAPIENELDRIDILYGFGIRLMGITYSESNALGSGLKEEKDGGLTNFGKKAVERM
                     NKIGMAIDCSHVGVQTTLDVIEYSKDPIILSHVGARSLWNTKRLTPDEVLIACAKKGG
                     VIGVEAAPHTTITEKNKEHSIESFMEHFEYIKNLVGIDHVAFGPDTVYGDHVKLHSVL
                     AAKFDIKKITGTKEHPKVEYVKGLENPTETSKNIVRYLVKHGYSDEEIEKVLGGNILR
                     VLKQVWK"
     gene            49108..49803
                     /locus_tag="OE968_000143"
     CDS             49108..49803
                     /locus_tag="OE968_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5058 family protein"
                     /protein_id="HCP7217460.1"
                     /translation="MDYLKLANHPLLWIASTVAVSIVVVQSLIFAIKSCKVGKTMGIT
                     DKQIKSAVKSSAISAIGPSMTIFAGMVSLIVTMGGPIAWMRLSFIGSVIFESMSAGFG
                     TDALGITLGSPEMTKLAFTNAVWTMILGSLGWIIFTLLFGHKLDKITNVISSGKKSFI
                     PIISLGAMLGSFAYLNADRVLRFDNGTIACISGMAIMVILCMLEKKKNIKWLREWGLT
                     ISMFSGMIIASVI"
     gene            49816..50493
                     /locus_tag="OE968_000144"
     CDS             49816..50493
                     /locus_tag="OE968_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7217461.1"
                     /translation="MSKVKSIYNEEYLPFKIRYGRLTLSLGIIAALVPGIILSFGFGI
                     MPPISALLASTMAIVSMSAPNYIIEPVSYSPILGIPGTYMSFLSGNISNMRLPCSIAA
                     QKAAEVESGTEEGSIISTIGIAVSILVNISILTIGVILGGSVLSKIPAEVVEKLNLIL
                     PALFGSVFGQVFLQDKKLGLVAIVISVLTIILSKQGIIPQSLVVLICVFGTMLIARAM
                     YKDKLSD"
     gene            50604..52205
                     /locus_tag="OE968_000145"
     CDS             50604..52205
                     /locus_tag="OE968_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HCP7217462.1"
                     /translation="MIYDLILKNGFIIGGTGNPGFYGDIAIKDNLIAKIDSKINSNTN
                     KEIDCCGKVITPGFIDPHVHEEIVAILDGKFEKFLKQGVTTTINGNCGHSITPYSSEN
                     VYEYMYKNGLLLEEEKKYLIDKNKCWNNFTEYCDLISKSGISVNMGFLLGHGTIRWSV
                     MGGSKDRPPTEKEKNEITDIINDGMKSGAFGISTGLAYIPSKYADIDELVDIAKQIKE
                     HDGIYTSHIRDYIGRYNAVKEAIEVGQKSGARVQVSHLSPVEIEAFDEILKARYNGVE
                     IMVDTVPRSSGHCMKKKRVIQFIMAISSSLFELGINGVMDALRNEEGRTLILKEAFIL
                     GDRGSIILLNTKDINMEKKSIREIATQKGIDEDKLLLDLLLDGDEELIFCLGGMYRAD
                     FPDKLHDDKIIDNPFVMVGSDCLFSVGGDMSWFELQRRGAFPIFFNMYRKSGVRLEEI
                     VRRVTSLPARQFKIKNRGILKEGLIADIAVIDMDNYSYSRSEDIDFSKPQLLANGVEY
                     VIVNGKIALENGEITENKCGEVLKR"
     gene            52654..53943
                     /locus_tag="OE968_000146"
     CDS             52654..53943
                     /locus_tag="OE968_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HCP7217463.1"
                     /translation="MRELLKVTLIVMLVLINAFFVACEFAMVKLRSSRIDTMITEGNN
                     NAKRCKIIKDNLNSYLSACQLGITLCSLALGWMGESTVKELILPIVSVFNLSESIIYT
                     ISISISFLIITMMEVVIGELVPKALALYNTEKIMLSTSFLLVGFYKLTYPIIYFFNLS
                     TDLFLKPFGYSQADEVDEPHTGDEIRLLVEESYKSGLIDESEQRLVDNIFEFEEKKIR
                     EIMVPRTDMVCIYESDSEEKILAILKEEGVTRYPVCRKNKDDILGFVHIRDLYNQKIN
                     ENKIELEEILRDIIYISENLTIDKALERIRKEKLQLAIVVDEYGGTSGVVTIEDILEE
                     IVGEIQDEFDKEETHIKKIGAGSYLVDGTESINYINKYFGLDIEHDGFDSIGGWISYM
                     LGSNIKVNQSVTFENYNFTILELDKLRVVKLIIKSVI"
     gene            53972..54652
                     /locus_tag="OE968_000147"
     CDS             53972..54652
                     /locus_tag="OE968_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HCP7217464.1"
                     /translation="MQKVEGIIFDMDGVLFDSERISLEFWMETFEKYGYTMTKEIYTS
                     VMGRNRKGIIEGLTDIYDSSVPIIDLYDEKTKNMIEFMERKGAPIKLGVNELISFLKE
                     NGYKMAVATSTKRERAVKRLAKANLKDYFDAIVCGDDVVNSKPNPEIFLKAAKKINVN
                     PKNCIVIEDSPMGVEAAYNGGIRCINVPDLKEPDEQIKSQSHKILENLLEVREYLKSL
                     NSKECHNL"
     gene            54753..55292
                     /locus_tag="OE968_000148"
     CDS             54753..55292
                     /locus_tag="OE968_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative ABC transporter permease"
                     /protein_id="HCP7217465.1"
                     /translation="MDNVGSLLYFLFNFFLYGFIGWIIENLYSYYKQGHFQEDGFLNG
                     PFKPMYAIAMSIIIEVSRFIDPNNIFALLLLCLVVPTVVEYITGILMKVYFNKVYWDY
                     SDYKYNSRGIVCLKFSVYWTILTFIGVRYFQVYIVDSLYSLIIPYWPIVVTILLVTLF
                     VDEILTIKFLRGNKDIVER"
     gene            55468..56487
                     /locus_tag="OE968_000149"
     CDS             55468..56487
                     /locus_tag="OE968_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HCP7217466.1"
                     /translation="MMGKIRFGIVGTSNIANIFLRAASRVKDFELVAVYSRNLEKARE
                     FGTLYGASIFFDDLEQMAKSKDIDAVYIASPNALHSKQTITCLKHKKHVLCEKSLASN
                     LKEVKSMIKTAKDNNVLLMEAMRITCVPNFKAVKENLYKIGKIRRFFGSYCQYSSRYD
                     KYKNGIIENAFKKELSNGALMDIGVYCIHPMVNLFGAPKTVKAVSHILQTGVDGEGSA
                     VFQYDDMDAIIQYSKVADSYIPSEIQGEEGSIIIEKLNLFEKAIIKYRDGREEDISIP
                     KEKAEEKPREIEGMYYELVEFISLINNNKIESNINSHENSIIVMEIMDEIRRQSSIVY
                     PADSI"
     gene            56775..57965
                     /gene="dltD"
                     /locus_tag="OE968_000150"
     CDS             56775..57965
                     /gene="dltD"
                     /locus_tag="OE968_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HCP7217467.1"
                     /translation="MRKLIYFITPFIIGVVFLFGLDKFLDSKTDELLREKNLLPIMDD
                     TLSDIKDKGVTANNHFLREKDIMILGSSELSNSTKQHPKYYFNTNRSKNKVFAIGRAY
                     TQTLQDAAILGSMNPNIDNKKVVLLISMQWFMEKDGVTSHHYQSRFSPIQFYRFLDNP
                     KISKQNKIEYAKKSSKLLWGSDEYKAEALYAKLYEPKTFPEKAEKVLLEPYFQGRKYC
                     IALKEKGILYKRLIKLDKKRATKRKRPINWSYERKKAIEDAKKRVGKNPLNIDKYYYK
                     EHFKDGIEQYKGRDKDVNLLTSKEFENYKLMLNVCTDLGIKPVVVLIPSMDKFYNLTG
                     ISEKERNQYYDKAQKIAESKGFEVLNLKDKGSDKYYLRDVMHLGTKGWVDVCERLFKI
                     FKEQ"
     gene            58086..59600
                     /locus_tag="OE968_000151"
     CDS             58086..59600
                     /locus_tag="OE968_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase"
                     /protein_id="HCP7217468.1"
                     /translation="MKIIEGIKKYSNTDRTALMCNGDKLSYKDLNEYSDAISVFLKDV
                     YKEEDTPIVIYGNKENMIMACMIGALKSGRAYVPLDISFPIDRVFEVTKEIKPKVLFN
                     FSDERNFGDINVIDMDKLNYIINEYQGKSLDKENWVKDDENAYILFTSGSTGKPKGVQ
                     ISSNNLDSFSDWISPYLNIDGSEKVIMNQPAYSFDLSVTTIYPGLIHGATLFSISKDV
                     LADYKELFRQFSISDIAVWVSTPSFAGVCITEKEFNSKMLPNLESMIFIGEALSKNLT
                     KELMSRFPNTRIINGYGPTEATVGVSVNDMTQKAIDDEKSLPVGYPMSNCKIKILDED
                     GNELKENEKGEIIIIGPSVSKGYFNNKEKTDEVFFYDEIDGVKWRAYKTGDMGYLLDG
                     NIYYCGRKDFQIKLNGFRIEIEDIENNLRKVHNVKNAVVLPVYKDEKIAYLKGIVELN
                     EKNDLSNIKNGMIIKKELGKYIPSYMIPRNISIISEFPTNINGKIDRKKLMEEI"
     gene            59600..60748
                     /gene="dltB"
                     /locus_tag="OE968_000152"
     CDS             59600..60748
                     /gene="dltB"
                     /locus_tag="OE968_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HCP7217469.1"
                     /translation="MIFSQYGDYFYLYILLLTSIPAVILGLMGKNIKYYGMLASLFMI
                     FLIVGIDVQLKYLVIFIILEVIIVKGYEYVRRKTKNKYIYWGFLFASMLPIIINKISP
                     VTSFGIIGFIGISYLNFRTIQMVIEIYDGAIKEVKISKMLYFMLFFPTLSSGPIDRSR
                     RFEQDLEKQISRKEYIEEYLLPGIKNIVMGVGYKFVIAFLINTYWVSRIPKDMSFINI
                     LSYMYAYSLYLFFDFAGYSLFAIGTGYIFGIQVPINFDKPFISKDMKEFWTRWHISLS
                     RWFGDYIFSRFVMSSMRKKRFKKRTTAAHVAQMITMITMGFWHGLTWYYVAYGVYQGL
                     ALVLTDIYQRKSKFYKKHKKDKWFERVQIFITFHIVCFGLLIFSGYLA"
     gene            60767..60997
                     /gene="dltC"
                     /locus_tag="OE968_000153"
     CDS             60767..60997
                     /gene="dltC"
                     /locus_tag="OE968_000153"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HCP7217470.1"
                     /translation="MQETVIEIFEDVLGTDEIREDLDLNLFETELLDSLAIIEVLLEI
                     ENRLGIELQPTDLERKDMSTVNNLVKFLETRK"
     gene            61214..61999
                     /locus_tag="OE968_000154"
     CDS             61214..61999
                     /locus_tag="OE968_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HCP7217471.1"
                     /translation="MSLNSIDRKKEILKLLDSKGKVNTKELVKRLEVSSETIRRYLEE
                     LENENKLKKVYGGAIKINYGVIEPEHIKRNNTNLDKKQSIAKYAAKFVNDNESIIIDE
                     GTTNLQIVDYIISVNNLKIITNSYPVLSKLISYENQGLFDGEVIFIGGKVNLKHQRTA
                     CPISIDAMKNLYVDKAFISSEGILDSFGISSIDQNKALLSKAYIKNSKESFVLCDSSK
                     IGIASMYKIADLEELDFVICDVEPPNEWKDKLNEINITWIEAK"
     gene            62278..64188
                     /gene="phnW"
                     /locus_tag="OE968_000155"
     CDS             62278..64188
                     /gene="phnW"
                     /locus_tag="OE968_000155"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HCP7217472.1"
                     /translation="MKKIYGEKIKAVVFDWAGTTVDYGCFAPLNVFIEIFKRRGIDVT
                     MEEARKPMGKLKIDHIREMCEMDRIKNIWSDKFGKVPTEDDVNELYAEFEPMLFETLE
                     EYTTPIPHVVETIEKLRKNGLKIGSTTGYTREMMNIVEPNAAKKGYSPDFLVTPSEVS
                     QGRPYPWMCYKNAEALGVSPMSSMVKVGDTISDVKEGVNAGMWSVAVIKGSSELGLTQ
                     EEVENMDKEELKAKMSIVSKKFKEAGAHFVIETMAELEDILIKIENETIKSDFVPEND
                     YILLTPGPLSTTKSVRASMLKDWCTWDVEYNNLVQDVRRRLVSLATQNTDKYTSVLMQ
                     GSGTFSVEAIIGSTISKDGKLLVIANGAYGKRMKDICNYLNIQFVDCTFKDIEAVDLN
                     VVENLLKENKDITHISMVHCETTTGRLNPIQEVGKLAKEYNKIYIVDAMSSFGGIEID
                     VEDFNIDFLVSSSNKCIQGVPGFGFIIANKEKLSKCKGIAKSLSLDVYAQWETMEKNN
                     GKWRFTSPTHVVRAFYQALLELEEEGSVEKRYARYKENQFTIASRLKSLGFDTLVNDN
                     AQSPVITTFLYPKNAKFEFMEFYTYLKDNGFVIYPGKLTDIDTFRIGSIGEVYPTDME
                     RLADVIEKFINR"
     gene            64547..65368
                     /locus_tag="OE968_000156"
     CDS             64547..65368
                     /locus_tag="OE968_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7217473.1"
                     /translation="MNEELSSLRFDGVGKCKGGIFDNVNISGTGKIEGSVKCSKFDSS
                     GSAKVFGTTECNEFFTSGLSKVEGNILASKVEISGLLRCTGNINSVEIDTSGIINVEG
                     SIKSDIIHGEGYLKANENIDCENINLSGILECNGFLNCEEVNISLNGTSNFNEVGASS
                     INIKKGHGDYCKKFRMLEKKHINFEKVSSNLISLGLLSIRKYTESKLFANIIEADEIS
                     LENSEVKVVRGKNIKIGKGCYVESLEYSESIEIDEDSIVGEIKNISEKIKLKKDK"
     gene            65409..66176
                     /locus_tag="OE968_000157"
     CDS             65409..66176
                     /locus_tag="OE968_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polymer-forming cytoskeletal protein"
                     /protein_id="HCP7217474.1"
                     /translation="MEKGSIKILGEGFISSGEYENIKIVGSSKSKGNVKSNEVKVLGD
                     AKFEGDINIKNFVVNGKTIIRGNLKAERVRVNGQLNIEGDAEIDDLVITAQQKVDGKL
                     KCNNVTIRGQLSVNENMYAQDIKIYGEMRNKSNIECEDIKVYGAIKCDGLLNGENIYV
                     YSGGGSYCKEIGATNIKIGRSKDAFSLIKIINIFSGKFKCNLIEGDTIELEDASIKDI
                     RGKSISLVDNCDVGNIEYSDNLSVSDNSTVKNSIKVG"
     gene            66184..66804
                     /locus_tag="OE968_000158"
     CDS             66184..66804
                     /locus_tag="OE968_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhbD family protein"
                     /protein_id="HCP7217475.1"
                     /translation="MEELISKKDLLSKTNISYGQLYRWKRKNIIPEEWFIKKSAFTGQ
                     ETFFPRDKILERIELILSMKEETSLDDIANMFMKKDINKEFDIDFILSKEVICNYTKE
                     IFQNLYKKEQSIGKKELLILSIIEKFLVKSIITFEELKLIVNIIEENFTSIYNESGKI
                     YLFRKFGVPFVVGCLDYKKVKFEKDVVKIIEIDLTKEINDISIKLS"
     gene            complement(67104..67691)
                     /locus_tag="OE968_000159"
     CDS             complement(67104..67691)
                     /locus_tag="OE968_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rubrerythrin family protein"
                     /protein_id="HCP7217476.1"
                     /translation="MNLKDSKTKENLLRAFAGESQARNRYNISASVAKKEGLYIIESL
                     FNYTADQEKSHAKQFFSKLKEFAGENISISGAYPVDLYDKTAQHLKAAQHNELQEWDD
                     VYKNFGKTAREEGFESIAKLFENIAEIEKVHGDRFGRYATDLEEGTLFRRNEDIQWIC
                     THCGHIHIGKEAPKACPVCLHPQGYFLDFKNSLFE"
     gene            complement(67777..68214)
                     /locus_tag="OE968_000160"
     CDS             complement(67777..68214)
                     /locus_tag="OE968_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HCP7217477.1"
                     /translation="MEDKYIVHFISKTKASMIKFIENKLSKNGLGELIPTHGNILTAL
                     YENNGILTMKEIAAKIGKDKSTVTVLVNKLINLGYLERQKCTNDKRITYIKLTKKALL
                     IEDTFNSISTQVKETAYHNITENEKQEFLRILKKINDNFKNAD"
     gene            68318..69316
                     /locus_tag="OE968_000161"
     CDS             68318..69316
                     /locus_tag="OE968_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhdH/YhfP family quinone oxidoreductase"
                     /protein_id="HCP7217478.1"
                     /translation="MNKKFKSLYITEEEGNFRRNIVEREVDTLPEGEVLIKVKYSSLN
                     YKDALSANGNKGVTRKYPHTPGIDASGIVESSSCDDFKIGEEVLVTGYDLGMNTSGGF
                     SEYIRVPSSWVVKLPKNLSLKEAMDYGTAGFTAALSVYKFIDSVDKNMGDVLVTGGTG
                     GVAVIATKILIKLGYSVVVSTGKLEEQKEVLLNLGVKDVIHRSEVDDNSGRPLLRPRW
                     AGVIDTVGGNTLATAIKTTNYCGAVTTCGNAGGVDFTSSVYPFILKGITLYGIDSVDC
                     PMNLRLKIWDLLSNEWKLDDLDDMVNVVSLEELNDSIDSIMAGKHVGRTVVDLEKI"
     gene            complement(69436..70362)
                     /locus_tag="OE968_000162"
     CDS             complement(69436..70362)
                     /locus_tag="OE968_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-nitrogen hydrolase family protein"
                     /protein_id="HCP7217479.1"
                     /translation="MSKENKNVRIAVVQASPVIMDLEKTVEKALGLIKEAGRKGANIV
                     VFPEAFIPAYPRGLSFGFVVGSRTMEGREDWKRYYDNSVPVPSATTDLLGKAAQEAGV
                     YLSMGITERDGNDINCTLYCTNLFFSPEGKLIGKHRKLKPTGTERCIWGEGDGSTLTV
                     VDTPYGKMGSLICWENYMPLARTALYAKGVKLYIAPTADSREEWQATMKHIALEGRCF
                     VIGCNQYVEKNTYPTDLNYYKELDAEPEIMCPGGSCIVDPFGKYVAGPIFNKEEMLIA
                     DLDLEKIVLSRLDFDSEGHYSRPDVFELIVHE"
     gene            70748..72352
                     /locus_tag="OE968_000163"
     CDS             70748..72352
                     /locus_tag="OE968_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HCP7217480.1"
                     /translation="MKAKIYYNGNIITMEDSICGDAILIKDKIIKKIGTKEEVFALKN
                     KDTEIIDLQGKTLMPSFIDSHSHLIAFATTLKLVPLEDATSFKDIVKKIQDFKESNNI
                     KKGDWIIGFSYDNNFLEENKHPDKSVLDSASSENPILISHASGHMGVANTLGLKQLGV
                     TNETRDPEGGHIGRVEGSEEPNGYLEENAFFNVASKIKQPSSNEIFNSIEKAQNIYLS
                     YGITTAQEGLMEENQFNILKAMANQNKLKMDVVGYVNLKKSKSVADNNREFIKKYINR
                     FKIGGYKIFLDGSPQGKTAWLSRPYENSDDGYCGYPIYKDEEVEKFIDISLKEKMQLL
                     THCNGDAAADQLIDAFEKVLNLKEQSSENNIRPVMIHAQTVRADQIDDMKVINMIPSY
                     FVAHTYYWGDIHIKNLGEDRAFKISPLKTTIEKGLIYTLHQDTPVIAPNMLETVWCAV
                     NRITKKGIQIGENEKISPLDALKGVTINAAYQYFEEDKKGSIKEGKLANLIILDENPL
                     TIDPMKIKDIKVLQTIREGEVLYSLK"
     gene            73168..74439
                     /gene="serS"
                     /locus_tag="OE968_000164"
     CDS             73168..74439
                     /gene="serS"
                     /locus_tag="OE968_000164"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HCP7217481.1"
                     /translation="MLDIKRIRENLDCIKKAMERRGEKNFNLDEVVKLDDERRKTLQE
                     VEVMKNELNTASKNIPNLIKEGKDVENEKIKLKELSDKIKVIDQNLKEVEDKMEYLLM
                     RIPNVPHPEVPQGETDEDNVEVRTWGKTTTFDFESKAHWEIGTELGILDFETASKITG
                     SRFTLYKGLGARLERALLNFYLDTNTKVNGYTEVIPPFMANRNSFLGTGQLPKFEEDM
                     FKIEGMDYFMIPTSEVPLTNIHANEILKFEQLPINYTAYTPCFRSEAGSAGRDTRGLV
                     RQHQFNKVEMVKIVAPEESYNELEKLTNNAETMLQLLNLPYRVVKICTGDLGFTASFK
                     YDVEVWMPSYNRYVEISSCSNCEDFQARRAGIRFKRDKDSKAEYVHTLNGSGLAIGRS
                     VAAILENYQQEDGSVVVPEVLRPYMGVSVIK"
     gene            74807..76312
                     /locus_tag="OE968_000165"
     CDS             74807..76312
                     /locus_tag="OE968_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HCP7217482.1"
                     /translation="MKIQNTEWGYIEWKHTYDENNPKQAMNIYIAVTMPGKKHFNHVH
                     YGQEQMIYILEGEGLYIINGVWKPFYQGMIFYIESGSTHETINTGDREIKELIVSNNV
                     DDVGESEVIDINPNNYLKKTLINYSESTLNLYAAVESIRGQFIDPFKIPLIIYDDSWN
                     IVLKNPYFPLFCFEKCNPMKFPQNCDCMNQKSSNQFVCEYGITIYNIPILYKSNSIGV
                     IRGGYVLLSDLNLDTEHNNLYDIPEGAARSIKRLLKQISKNIINFCSFNDIRKDLQEK
                     EKTIARTYHYGEQLEMNLKVAQDMVTNLRINHHFLFNTLNSMASIALDDGSYDLYSAI
                     IDLSRMFRYTMRSDLRFVELESEILYIKNYLNLQKLRYGDALKVKYLIPEKLYNLSVP
                     FNFIQPIVENAFTHGFRDIDTEKRIEIIARLDSQYAIIEIHNNGTILDGNNIDKIKAG
                     IRSNNGHGLSLIYTKFTSAYGNNFDMDIKSSDNEGTYIMIKIPIENYKEYV"
     gene            76426..>76554
                     /locus_tag="OE968_000166"
     CDS             76426..>76554
                     /locus_tag="OE968_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator"
                     /protein_id="HCP7217483.1"
                     /translation="MRRALIIDDEEAVLKIITHFIEMKDMPIKIVGKATSGDEAVDK"
BASE COUNT        29112 a         8787 c        13299 g        25356 t
ORIGIN      
        1 gcaaaagctt taaaagaaga attaacagaa ggtgaggtat atgcacgact ttcaagtgat
       61 tattttgcaa ttttctgtga ttataaaaat ggaagaaata aaattataag aaaacttgat
      121 aatatacgaa gtaatattga aagtaatttg agtatagtct ttgaaatttc tctgtgtgtg
      181 ggtatttatt ttgttgaaga aggtgaagta gatattcaaa aggctgtaaa taaagcaaat
      241 atggctaggt ctgttgctaa aggtaaaaat ataaattatg ctatttataa tgaagatgtt
      301 aggaataagc ttagtgagga atcaatgatt ttagacgata taaaaatagc attggtaaaa
      361 aatcaatttg aagtgtatta tcaacctaag ttttcacttg taactggaga aatgataggg
      421 agtgaagcac taataagatg gaatcatcca gaacatggtt ttataagtcc cgcagtattt
      481 attccaatag cagagaaaag taagttgatt ttaaaaattg ggagatttgt atttgaaagg
      541 gtttgcaatg atttatatga atggaaaaag caaggtaaaa agatagttcc agtttcagta
      601 aatttatcta gggtcgagtt gtatcaacca gatattgtaa aatttatcaa taaaacaata
      661 aaaatgtata atttaagttc agatttcatt gaaatagaga taacagaaac tgtggctatt
      721 aatgagttaa atattttaaa gaatgtttta aatgagttga ggacgtatgg attttctatt
      781 tctatggatg actttggtac aggatattct tctattagtt gtttaagaga tatgccaatt
      841 gatatattga agctagataa gtcttttctt ggtggcattg aacatgatga gagaagtcgc
      901 aatatagcaa aatcaatagt gtctctagca aaatcactag atttagttgt aattatagaa
      961 ggtgttgaga gtaaagaaca agctgagtta atgaaacaat ttggatgtga tttagttcaa
     1021 ggattttatt ttgcacgacc aatgccagct aagaattttt tagatttact ttaaaacaaa
     1081 atttgatttt tatataaagc actattatga atgcttgatt ttaataaatc attgctaaat
     1141 aattagtgtt tttttatttt atcaatgtat tgtctaatat aaagcaaaaa ataattgtat
     1201 tttataaaaa ttatattaaa aataaattta ttttgctaat aaacatgtta ttaacaaaag
     1261 aatagtacta taatgtatag atgataaaaa ctttaataaa aatttagtgt ataggagttg
     1321 tttaagtatg atagatataa gtattgatga caaacttaag gaaagatggc ctaatgctaa
     1381 gctgggttgc attcaagcaa aagtagcagt aaataaaagc tcagaaaaat taattaatga
     1441 aataaatgag ttttgtgata ctataaatca aagtctaaaa gttgaagaca ttacgaaact
     1501 agataaaatt aaagatgcaa gaaatgctta taaagagctt ggaaaaaatc caagtagata
     1561 tagaacatct tcagaagcat tggttagaag aattattcaa gggaagggtc tttatacaat
     1621 aaataatata gtagaaataa acaatttaat atcaataaaa tcattatatc cagtaggtac
     1681 atataatgta agcaaattac attcaccagt atgttttact gtaggagatg aaggagaaca
     1741 gtataagggt attgggaaag aattaataaa tatagaaaat cttcctatat tgtctgattc
     1801 agtgggtaaa tttgggagtc caactagtga ttctgaaaga gcaatgataa cagaagatgc
     1861 aaatgaaata ttaatttgta tattttcttt tagtcaagaa tctgatattg aagaatattt
     1921 tggatatgct aaggaattac ttaaagaata tgcagatgga aaagatatag aaactaaaat
     1981 aattaaatag aatctatata acaacgttat gttaagctaa aattcaatat aaaaataagt
     2041 taagataaag aaactaacac aaaattagtt tcttttttaa aatagtagtt tagtgttaca
     2101 aaaatagata gatagtccca cgattattaa aagtatggta atatattaat atagcagaga
     2161 ttgtgtttaa gggattttga aaggggggat ttataataat cattttatct aaaagataaa
     2221 atggttttat agaaataact atatatttaa aaatataaat aatgatacag taatttgggt
     2281 atataaaata aggcatacat ggttttgttt aaaaaccaat aaggtacata ggtaattaca
     2341 atgtaaggaa ggatttaatt atgattgatg gaaaagaggt aaaacaagaa agtggacaaa
     2401 aaaatctaaa atttaagata gctatagtag taggtgtttt gtttgtagct tatataggaa
     2461 tggcaatctt ttttagaaat catttttact ttggaacgac tattaatggc gtaaaggctt
     2521 caggaaaaac agttgagcaa gtaaatgatt tgttagcatc tagtactaat tcctatactt
     2581 taaacttaga ggaaagaaac aataagaaag aacaaataaa agcaaaagat attgatttaa
     2641 aatttacacc agatgataaa gttcaaaaga taaaagatag tcagagcgct attggatgga
     2701 ttggtggaat atttaaatct aaagagtata ataatatgat aactctttca tataataaag
     2761 atttactaga aaaaaggttt aatgctttat cttgttttga tagtaaaaat gttgtagaac
     2821 ctaagagtgc ttatcctaag tatgatagca ctaaaaacgc ttatgttata gtaccagagg
     2881 tacttggaaa caaagtgaaa aaagatgatt tttataagtt agtacaaaac tcaattaatt
     2941 ctgggaatac ttctatttct ctggatgaaa gtaaagttta tgaagcacca aacaacacaa
     3001 aggattcaga aaagttgaaa caagctatta agacattaga taagtatgtt ggtgtagtcg
     3061 ttacatatga ttttagtgac cgtaaggaaa ctttagatgg ttctgaaatt aataaatggt
     3121 taaaagtaga ctcagaaaag aattatgaca taacttttga taatgatgct atggtagaat
     3181 atacaagagg tttaagtaaa aaatacagta cttttggtga ctcaagacca tttaaaactg
     3241 ccacaggtaa agatattaca atttcaggtg gaatttatgg ttggttgata gataaaaaga
     3301 aagaagctga agcattagtt gatgttgtaa aagctggtaa aaatgttaca agagaaccta
     3361 tttacataca aaaagctgta tctcgtaata aagatgatat tggaaataca tatgtagaga
     3421 ttagtctttc tggccaacat atgtggttct ttaaaaatgg agaaatgctt gtatcaacag
     3481 acgttgtaac aggtgattta gctagaggat ttgctacacc atcaggtata tatcctctta
     3541 attataaggc tagaaatgtt tcattaactg gtcaaggtta cagttcacct gtaagttatt
     3601 ggcttccatt taatgggaac ataggcattc atgatgctac ttggagaaat tcttttggtg
     3661 gaagtatata taagtcttca ggttcacatg gatgtgtaaa tacacctttt tctaaggcaa
     3721 agaaaatata tgaaaatata gaaccaggta caccaattat tttatactag taaatgtgtt
     3781 gctaacagtt aagcgaagtc atcctagttt atttaggatg gcttcctttt tatataaagc
     3841 ttattgaagt ttacagaaag actacttaaa aggagaaata cataatgaat gaaaaattaa
     3901 ctaaaatttt agaagaagct aagaatgatg atgaatttag aaaggaactt ataaaaacaa
     3961 gagaacaacg tgatgttatg gattcatttt gtaaggttgt tacatctaga ggttatgata
     4021 tgacagtagg ggaacttttt tctatgggag aagaatatac atccaatcta ctgaaaagtg
     4081 taaatggagg agcagcatat cctattgaag attggagtga ttggtacgag gattttttta
     4141 taatgttgtc gaatatatag agtaactaat gatattatct acttaagatt aatacattgc
     4201 cttaaaataa aactattaga actaggtgta agttttatca atctttaaaa atattgattt
     4261 atttctaact agatataaaa aaattagatt aaaaataagg tgacaaaaat cgatatagct
     4321 tgatgattta taaaagttag ataaaatagt gcgagatatt tctaaaaatt caaaaaaaac
     4381 aataaacttc aatggttaga ggttgaaaaa gaatataaaa aacttttata tgtaataaat
     4441 taaattaaaa ttataaaaaa aataaaataa aaatttaaaa tgtcgacata acgttaattt
     4501 taaaacaaaa taacgctatt gacaaactat atcgctttaa attataatta ttgaaaataa
     4561 tggtatttaa aaaccatact catgtcatag tctaaaagta agtcaaaaaa ggatgtaaat
     4621 ctaggcaagt actattctaa aatatgtttt attaagaaat aaacgttgaa aaatattaat
     4681 tattatataa aaatgctgtt tatactttaa caatgaggta gtaatctaat tagaataaaa
     4741 aaatctaatt ggttatatac atagtaaaaa ggtaagagag gtgatttgga tggcttttga
     4801 aataataaaa agcattgttg aggcagagca gacagcagac agtatcaaag taaaagctgt
     4861 tactgatgca gagtctatca gagctgatgc tgtaaacaaa tgtgaaagca tatttgctga
     4921 tgtaaaaaaa caagcaaagc ttatggaaga aactcttatt gagaaggcag tcaccgacag
     4981 tagagcagag gttgataaaa tcttagctaa tgctaaaagt gaatgtctga aaattgaaaa
     5041 aactgctgaa gaaagaaaaa gtaaggctat tgaagcggtt attggaaagg tagtgagata
     5101 atatggcaat agttaatatg aacaaaatat ctattgttgg cttagaagct caaaaaagcc
     5161 agattttaaa gctacttatg aaccgtgggt ttgttcagat tgatgatagt gcctttctta
     5221 ctgaggagga ggaattaaaa aattatcttg taaaagatag tgaagaatct gaagttataa
     5281 tgctagagca gaaaatgtct catgtaaacc aagcaattaa tattgtttct tcactagtga
     5341 aacaaaaaaa atccctactt gcaccaaaaa gagagtttaa caaaattgat agtgaaaaag
     5401 aagggcaagt ttatgctgaa gctctggagt taaacaattt gcacaaggag ataggtacaa
     5461 taaggtctaa cataaactta cttaacaaca ataaaagtat gttagaacca tgggtgaact
     5521 ttgatattcc tattgaaaat atggaaacta agtatacaaa aactatactt ggaactgtgc
     5581 ccataagcgc aaacattgat gctttaagag taaaattaga agatgaaata ccagaaagtg
     5641 ttattgggat tgtcaattct gacaagttaa tgaactatgt ttatttaatt actttaaaag
     5701 aaacttttga tgatgtttta gaagttttaa aagaatttaa tttttcagtg gtttcattac
     5761 caaatgaaga aggtacaccg ttacaagcta tcaagaaata caatgaaatg ataattagac
     5821 aggaaaacgt ttctaaggac aaaacagagg aaattaaaag acatgcagat agtatacaca
     5881 tgcttgaaaa cctatatgat ttttacacta tagaaagaga ccaaaaaaag attatagaga
     5941 gacttgtcaa aacaaaaaca acattctgtc ttaatggttg gttaccaagc aaaagggcag
     6001 atgaattaat taaagaaatt acagaaaagt ttgattgttg tgttcagact gaagaaggaa
     6061 gtaaagaaga aggcttccca attctgcttg aaaacaataa attagtaaca ccttttgaaa
     6121 gtgtaactaa catgtacagc tatccaagta caaaagatat tgacccaaat acaattttaa
     6181 ctttcttctt tgttatattc tttggaatga tgctaagtga cgccgcatat gggttaataa
     6241 ttgcagtagt ttgtggattt gttgtatata aattaaagat acaaaaaggt gaaggaaatt
     6301 taattaaact tattggtatc tgtggagttt caactactgt atggggtctt atattcgggg
     6361 gtattttggg ggatttaatt cctataaaag cattaattaa tcctttagag gatgttatga
     6421 cacttatggg aatgtcgtta ctgttcggta ttatccatat atatgtaggt ttgggaataa
     6481 aagcatatac attaataaga agtggaaagg taatagatgc aatctttgac ataggttttt
     6541 ggtatttgtg tataacaggt gtatgtctac ttataatacc ttttgttgca ggggacatag
     6601 gtgtattttc agaagtagga aaatatttag caattatagg tgctataggt cttgtactta
     6661 ctcaaggaag aagctttaaa ggtattcctg ttaagctttt taaaggattt tcaagtctct
     6721 atggtataac aagttatttt gctgatatat tatcttatac aagaattatg gcgctttgtt
     6781 taacaacagg agttatagca caagttatca accttttagg ggctatagct ggtccgatac
     6841 ttgcagttgt aattggtgtt gtaggacaca caataaacct tcttataaat gcactaggtg
     6901 catatgttca tacaagtagg ttacagtatg tagaattttt caataagttt tatgaaggcg
     6961 gaggagttcc ttttgttccg tttaagtata aaacaaaata tacaagcatt aataaaaagg
     7021 agatgtaaat atggaatttt taaacgcgtt aggaaatggt caatttttgg caatatcagg
     7081 agctgctata gcagcattat ttgcaggtat gggttctgct aaaggtactt caatagcagg
     7141 tcaagccgca gcaggtgttg taacagaaga ccctagtaaa ttcggtcaac ttctagtttt
     7201 acaacttctt cctggtacac aaggtctgta tggatttatc atagctttcc ttattttatc
     7261 aaaagcaggg attattggtg gagatgcaat accaacatca gctcaaggtt tacaacttct
     7321 tatggcagga cttccaattg gtttagttgg tttagtatca ggtatagcac aaggtaaagc
     7381 agcagcagca ggagttggaa tagttgcaaa aagacctgaa gaacttggta aagctataac
     7441 atttgcagca atagttgaaa catatgctct tttaggacta cttgtttctt tcttagctta
     7501 caatggaatt gcaattggtt aattataaat tataattcat aagtaaaaaa aatgaaaagg
     7561 aggaagcact cctatgggta atgaacaaaa aatgattgac agaattatag ctgatgccaa
     7621 acaagaagca caagaaatat tggataaagc taaaagtgaa gcagatttaa aagtaaattc
     7681 agctaatgaa aaagctgaaa aggaaatggc ttcctataca aagcttgcag aggcagaagc
     7741 agaaaaagcg gcttctaagg aaatatcagg agcttatatg gaggctaaaa agcaaatatt
     7801 atcaaaaaaa caagagattt tagaagaggt aattttagaa gctaaaaaca aacttttaaa
     7861 tcttaaagat aatgaatatg aagagattat actaaacatg attgaaaaat caaattgtac
     7921 agatgattca gagatagtat tatctaaaaa agataaaaaa acattaaaag atgtgctatc
     7981 aaaaaaaggc attaaagtgt ctgatgaaac tagagatatt actggaggtt tcatagttaa
     8041 aaaaggtgac attgagtaca attattcatt tgaagccata attgcagtag agcatgaata
     8101 tattgaacaa attgcagcag aaattttgtt taattaagga ggggttaaaa aatggcagaa
     8161 gaaaaaactt atccctatgc cgttgcacga ataagagtgc ttgaaaaaca gcttcttaac
     8221 agacaaatgt ttattcaaat ggcagaagcc aaaagccctg aagactcttt aagaattata
     8281 gctgaggcag gttatgctga tacatcaaat aataatatac ataattttga gaatattttg
     8341 actcaagaat tatcaaagac atatgaaatt cttaaaagtc tagctcctga agaaaaattt
     8401 gttgatgtat ttctttataa aaatgactat cacaatttaa aagtgctgat taaagaagaa
     8461 atttctggtg tagatggtga gaaatattta attgatggag gtacaattcc tcttattaag
     8521 cttagagaat ctttagcaaa tcgtagtttt agtgatttac ctaagataat gtcatcagct
     8581 atattagagg catttgatgt ttataataag acacaaaatg gccagatggt tgatattgtt
     8641 ctagataaag caacctttac cagtatgaaa gaaactgcta aagaaagcca aaacaaattt
     8701 gtaatagatt atgttatgaa agtttgtgat ttaacaaatc taaagagttt tataagagtc
     8761 aaaaatatga agaaagattt tgatatgttt atgaatgtgt ttgtttcagg tggctcactt
     8821 gataaggaaa aattcttaga agctttttcc tcagatactc cagcatcatg ttttaaatct
     8881 acttcttact ctgatgtctg taaaaatggc atggatagtg gttttactgt ctttgaaaaa
     8941 ctttgtgatg actatcttat ggaatatgtt agaggagcaa aatttaagcc tcttacatta
     9001 gaaccactaa ttgcatattt atatgctaaa gaatcagaga taaaaacaat tagaattatt
     9061 ttgactagta agcttaataa tatagacgca gatactataa aagaaaggct aagggatgct
     9121 tatgtataag gtaggagtag ttggagataa agatagcatc atgggatttt tagctcttgg
     9181 aatagatatc ttcccagcct atgatagtga cgaaattaaa aaaagtatac ataagttggt
     9241 tgaagatgaa tatgcgataa tttatattac agaacaggca tcattgcttg caaaagaatc
     9301 aatagcaaaa tacaaagatt accaacttcc tgccattata gttattccag gtattggagg
     9361 aagtatggga ttaggtatga atgaagtaag agaatctagt aaacgtgcta taggtgcaga
     9421 tatattattt aaagaataga tgaaagttga ataaaagaca atctcaaatt ttattggtgc
     9481 taaatatatg tgctaataaa atataggagg gaatatttaa attttgataa agtatatgat
     9541 tgcaggtgag agaatatgaa aacaggcaca attgtaaagg tgtcaggacc gcttgttgta
     9601 gcggagggca tgagagatgc gaatatgttt gacgtcgtaa gagtttcaga taaacatctt
     9661 ataggcgaga ttatagaaat gcatggagat aaagcttcta tacaggttta tgaggaaact
     9721 tccggtctag gaccagggga agaagtagtt tctcttggaa tgcctatgag tgttgaactt
     9781 ggaccaggtc ttatttcaac tatttatgat ggtattcaac gtccacttga aaaaatgtat
     9841 gatatttcag gtactaatat aactaaaggt gttgaagtat cttcacttga tagaacaact
     9901 aagtgggaat ttaaacctaa aaaatctgtt ggtgataagg ttgtagcagg agatataatt
     9961 ggtggcgttc aagaaacagc agtagtagaa tgtaaaatta tggttcctta tggagttaag
    10021 ggtactataa aagaaatata ttctggtgaa tttactgttg aagatacagt ttgtgttatt
    10081 acagatgaaa aaggtaatga tatacctgta actatgatgc aaaaatggcc agttagaaaa
    10141 gaaagaccat atagagaaaa gaaaacacca gattcacttc ttgttacagg tcaaagagtt
    10201 atagatacat ttttcccaat cacaaaaggt ggggtagcag ctataccggg accttttgga
    10261 agtggaaaaa ctgttacaca gcatcagctt gctaaatggg cagatgcaga tatagttgta
    10321 tatataggct gtggcgagcg tggaaatgaa atgacagatg ttcttcttga atttcctgaa
    10381 ttaaaagacc caagaacagg cgagtcactt atgcaaagaa ctgtgcttat agcaaacaca
    10441 tcagatatgc cggttgctgc acgtgaagct tctatataca ctggtattac aatagctgaa
    10501 tattttagag atatgggata tagtgttgca cttatggcag actctacatc aagatgggct
    10561 gaggctctta gagagatgag tggtcgttta gaggagatgc ctggtgaaga aggttatcct
    10621 gcatacttag gttcacgtct tgctcaattc tatgagagag caggaaaggt aaattgtcta
    10681 ggtatggatg aaagagaagg aacacttaca gcaattggtg cagtttctcc tcctggtggt
    10741 gatacatcag aacctgtcag ccaagcaacg cttcgtatag taaaagtatt ctggggtctt
    10801 gatgcatctt tagcatataa acgtcatttc ccagcaatta actggttgac tagttattca
    10861 ctctatcagg aaaaagttga tgtatgggca gataaaaatg taaatgataa tttctcagct
    10921 caaagagctc aagctatgaa acttttacaa gttgaatctg aacttcaaga aatagttcaa
    10981 ttggttgggg ttgattcact ttcagatgga gatagattga tactagaggt tactcgttct
    11041 ataagagaag acttccttca tcaaaactct ttccatgaag ttgatactta tacatcactt
    11101 cataaacaat atagaatgat gggacttata ttaaaattct ataagtcagc acaagatgct
    11161 atcaagcaaa atgttactat aaacgatatt atcaagcttt cagttcttga aaagattggt
    11221 cgtgctaagt atgtagaaga aggcgatata gatgcagctt acgattcaat tgaagatgaa
    11281 atagacaacg agcttgcaga ccttattaaa aagagggggg ctgaagaact atgataaagg
    11341 aatataagtc aatacaagag gtagccggtc ctcttatgtt aataaacggc gtagaaggtg
    11401 taaaatttga tgaacttgga gaaattgaac tttcaaatgg agaaattcgt cgttgcaaag
    11461 ttctagaggt aaatggagat actgcacttg ttcagctttt cgaaagctca acaggtataa
    11521 accttgctga aagtaaagtt cgttttttag gaaagagtct tgactttgga gtttcaccag
    11581 atatattagg tcgtgttttt agtggaatgg gtagacctat tgatggaggt ccagaaatta
    11641 taccagataa aagacttgat ataaatggag ctccaataaa tccagcagca cgtgattatc
    11701 cggccgagtt tatacaaact ggagtctctg ctatagatgg acttaataca ttggttagag
    11761 ggcaaaaact tcctatattc tcagggtctg gtttgccaca tgccaatctt gcagttcaga
    11821 ttgcaagaca ggcaaaagta cgtggaactg attctaagtt cgccgttgta tttgctgcag
    11881 ttggtataac ttttgaagat gctgaatttt ttataagcga ttttaaagca actggtgcaa
    11941 tcgaccgttc tgtagtgttt gtaaaccttg caaatgaccc agctgtagag cgtgtatcta
    12001 cacctagaat ggcacttaca gcagcagaat accttgcttt cgagcaagat atgcatgtac
    12061 ttgttataat aacggatatt acaaactatg cagaggcatt gcgtgaagtt tcagcagcta
    12121 aaaaagaagt tccaggacgt cgtggatatc caggatatct ttatactgac cttgctacta
    12181 tgtatgaaag agcaggaaaa atgaaagggc atgaagggtc tataactatg attccaatac
    12241 ttacaatgcc tgaggatgat aagacacatc caattcctga ccttacagga tacattacag
    12301 aagggcaaat tatacttagc cgtgaacttt ataaaaaaga tatacagcct cctatagatg
    12361 ttttaccatc actttctcgt ctaaaagata aaggtattgg taaaggtaag actcgtgaag
    12421 accatgcaga tacaatgaac cagctttttg cagcttattc aagaggtaag gatgcaaaag
    12481 aacttatggc tatacttggt gaatctgcac tttctgagat tgatttaatg tatgctaagt
    12541 ttgcagatga atttgagaaa gaatatgttt cacaaggatt tagaactgat agaactattg
    12601 agcagacatt agaaatcgga tggaagcttc ttagtatgtt accaaaaagt gaacttaaac
    12661 gtatccgtga tgaatatttt gaaaaatata tgcctaagga gtgatatctg tggctagatt
    12721 aaatataaat ccaacacgta tggaaatgac tagacttaag aaactcctta aaactgctac
    12781 aagaggtcat aagcttctta aagataaact tgatgaactt atgaaacaat ttcttgagat
    12841 tgtaagagaa aataagcgat tgcgtgaaga agcagaaaat gctcttgata ctgcttataa
    12901 aaactttata atcgcaagag cagttatgag tcaggagtat ctgggttcag cacttatgat
    12961 gccaaagcaa tcagtttcag tagatgtttc tacgagaaat ataatgagtg ttgatgttcc
    13021 tgtgtttgac tttaaaactg aaaacaatca aagtgatatt tatccttatg gtcttgcttt
    13081 tacatcaggt gaattagatt ctgctatgga agctttctca gatgctatgc aaccactttt
    13141 aagacttgca gaaagtgaaa aaagtgcaca gcttcttgca caagagatag aaaagacacg
    13201 tagacgtgtt aatgctcttg aaaatgtaat gataccaaat tacattgaga ctattaagta
    13261 tatagctatg aagcttgaag aaaatgagag agcaagtact actagactta tgaaggttaa
    13321 ggatatggtg cttaaaaaag cacttgaaga aaagaaaaaa aatgatttgg ttgtataatt
    13381 aaatacttat aaaaataagt ctaacattct actttataga ggttagactt attttttatg
    13441 tttaaattaa aatgtagata ctataaaaat taatatattg tttaaaaaca gactgtattt
    13501 aactaaaaat aatatattta acaaaaattt ctaaaaatta acgaactgtt aatttacact
    13561 taactttata ttaacaaatt aggtgtatta tataaacata agcaaaaaca ataaaaaaca
    13621 aataaaaaaa ggaaaaaaca caaaggggga agatatgaaa gaatttatat ttacttgtct
    13681 gtgcattgta gtgattacat ttatgacaag ttgcatatca acaacaccac aaactactca
    13741 aggaaaagga aataataaac ttacaatata tgcagcacta gaggaagagc agatagctta
    13801 ttatatggaa ggttttagag aagagtatcc caatatagat gtagagatag ttatggattc
    13861 tcatggtgta atagcttcaa aactattagc agaaaaagat aatccacaag cagatattat
    13921 atggggatta tcagcaatga acatgataga gctaaaaaaa gatggtgcac ttgaagcata
    13981 taagcctaaa aattatgata aagttgataa aaaatttaaa gatactgaag atgatgtatc
    14041 ttgggtagga atgagtgtcc cagagacagc aatagtagtt aattataagg aacttaagaa
    14101 actaggtata gatattccaa aaagttatga agatttaata aaaccagaat ataaaggact
    14161 tataacaatg ccaaatccag catcatctgg aacggggtat cttacagtat cagggcttat
    14221 tcaaatgatg ggtgaaaaag atgcttacaa ttacatggat aaattacata aaaatatagc
    14281 cacatataca cactcgggtt caaaacctgc gaagttagct ggctctggag agtatccaat
    14341 aggtattaca cttggatata gagctacaca acaattatct agtggagaac ctatagaggt
    14401 tgtatttcca aaggaaggtt caggttggga cttagaagca aatgccttag ttaaaaaaga
    14461 taatataaaa aaagaagcaa agctattttt agattgggca ataagtgatt cagctatgga
    14521 tagatatgca catgaagtag cagttacttc cataaagaca gataatccag ttccaaaagg
    14581 ttattctaaa caaccatttg aacagcttat aaaagaagtt gatttaaact ctgctgccaa
    14641 aaacagaagt acagtactta aaacttggga atcaaaatac ggttcaaaat ctgaaagtaa
    14701 gtaaagttta aattaataat ttagatgaaa gaattttaga agaaaaagta ggatataaaa
    14761 tttaaaataa aaaaataact atataaggag agataagata tgagttactt aaaaataaat
    14821 aatgtgttta aaagttatga ccaaaaaaag gttttaaata atattagttt ggatattgaa
    14881 gaaggggaat ttctatgttt actcggacct agtggatgtg gtaaaactac attacttaga
    14941 ataatagcag gtcttgaaga tgtaaatagt ggaactataa ttctccagga taaagatatt
    15001 acaaatttag agccatcaaa gagaggtttt ggtatagtat ttcaatcata tgcattattt
    15061 ccgaatatga ctgcttataa caatatagct tttccactaa aagagagaaa agtttcaaaa
    15121 gaaaaaatag ataataaagt taaggaagta cttgaaacag ttggattgac taatgaagct
    15181 cataaatacc ctaaagcatt atcaggtgga caacaacaga ggattgcaat agcaagagca
    15241 ttagctcttg aaccaaagtt tttactttta gatgaaccaa tgtctgcatt agatgcaaag
    15301 gttagacaca agcttagaat ggacattaaa agattacaaa aagaacttaa tataacgaca
    15361 ataatggtaa cacatgacca agaagaagct ataactatgg cagataaaat agctattcta
    15421 aatggaggag atataatgca aatagggact ccagaagaaa tataccaaaa tcctcaaaac
    15481 ctatttacag ctcaatttat aggagataca aactgttttg ataatggaga ttctatatta
    15541 actgtaagac cagaatatgt tcaaatagag aaatcgacaa aagaaaacta ccaagggata
    15601 atatcaaata tagagtttag agggaattta ttgagagttg aaataaaaga taaattaaat
    15661 gaaaatttca taataagtga tgtttctata aaagagtggg ttaatttaaa tttagtagaa
    15721 ggtgaccttg taaaaataag tatagacgaa aaatactatt taaagtatcc aaaagttaaa
    15781 ggagcataag tgtatgaata ataatgctat aagttctaaa agtataagtc ttaaatcaaa
    15841 aatgaattta gatataaaaa aatgtatgct tacagtatta gttatgtctt tagtaatatt
    15901 tttattagca cctataatat atctatttgt acaggctttt ttagataaag atggagtctt
    15961 tgtaggatta caaaactttc aagaatactt ggcttctgaa tctctattaa attctctaaa
    16021 aaatacagta tttgtatcag ttatatcaac tgtaatatca ctaacacttg cattagtata
    16081 tgcatatgca ttaactagaa caaagattaa atttaaaggt ttttttaaat cattagctat
    16141 gtttcctatg tttgctccaa caatgatgca tgcaataggt ctagtatatt tatttggaaa
    16201 tcaaggtttg gtaactaatt tacttggagt gcatgttcca atatatggag cagtgggaat
    16261 aatattggca caaattatat atgtatttcc tcaatcattt caaatacttt atatatctct
    16321 aagttcaacc gattatagac tatatgaagc tagtaatact atggggataa gcaagataag
    16381 agaatttata agcataacaa tcccaagtat aaaatactct ttaataagtt ctgcattcgt
    16441 atcgtttaca ttatgtttta cagattttgg agctccaaag gtgataggag gagagtttaa
    16501 tgtattatca atagatgtat ataagcaaat tatagggcaa cagaatatgc caatgggagc
    16561 aactgtatca atattacttt taatacctgc aataatatcg tttatagtaa ctaaaaaaat
    16621 tgaaaaaaat caaaattcat atataacttc aaagtcaatt ccatataagg ttaaaactaa
    16681 taagttaaga gatagtattt taggaggggt tgtaggaatt attgcatttg gtataatagc
    16741 tgtaatgtta actgtaatct tatcttcatt aatatcagtt tggccatatg atttaagact
    16801 gacactggaa catttttcta tgaaaaacag tattgatggg attaaaccat ttataaattc
    16861 aataaaaatg tcactattta cagctattct agggacgagc tttgttttct tatttgcata
    16921 tttgaatgaa aaaacagaaa aagctccata tttaaaatca tttgggtatt ttttaagtac
    16981 attgcctatg gcattgccag gattagtttt aggtatagct tatgtattat tttttaataa
    17041 attagagttt aattttatgg atacaatata cattaagaat ttgtttaatg gattatatgg
    17101 aacattactt ataatggtta tatgtaatat agttcatttc ttttcagtag catttataac
    17161 agctactact gctattaaga aagtagataa agaattagat atggtagcta aatcaatggg
    17221 aataaacagc gcatcaattc ttaagaacgt aactatacca ctttgtttgc cagcagtttt
    17281 agagaacttt atgtactttt tcctaaactc catggtgaca atatcagcat tagtttttat
    17341 atatactgca agttcaaaag tagctgcaat atcaattgta caactagatg ataaggggag
    17401 tactgcacag gcagcagcac tagctgtgtt aatattagtc acaaatatat tagtgaaagt
    17461 aatatatgaa tttataaaga atcgtttaga aaaaagaaca aactttaatt aaataattta
    17521 tcttataaaa acacaaattt aaaaaagtct attcttgtga tttattattt aaagaataga
    17581 ctttttaaat ttattattga tattgtttat taattttcct tttgttatca tacatttgag
    17641 aatctgcacg acgatatgta tcaaataaag aaacatctac tttttcatca aaaatagcat
    17701 atccaataga cattgataat tttaattcat tagttgagtt ttcttcaact atttttaaat
    17761 taatattatt tataatatta tttatttctt tgtgagataa attttttaga ataattatgt
    17821 attcatcacc tccaatacga taaactatat attttttatt tattacatat tgtataattt
    17881 tacttgcttg cttaatatat aagtctcctg tctgatggcc aaatttatca ttaatctttt
    17941 ttaaaccgtc taaatctatt gatatgatag atattagatt ctttagattt gaattgttta
    18001 agttattcat atctatttca aaagcatttc tattttttag gcctgttaaa taatctgtat
    18061 tagcaaaatc agtatatgta ggattagata ttcttttaaa tagaatcact gcaatcaatg
    18121 ctgatattag acaagttaat aatgctatta ttggtgtaac tatacttata aatttaaatg
    18181 tattgtattg atgttttgct tcaaattcaa ttcctattac tccaacaacc ttaccaacat
    18241 cattgtgaat aggaaaatac gatataaata tgtatcccca agatgttgat ttaatctttt
    18301 taggtaacaa tatatgatta tctaatgctt tgttaaggtc tccccaaatc tctttttcta
    18361 tcaaatcacc agcatttcta aaatcactcc tagatgaatt taaaccatca acaacatata
    18421 ctagtgatcc atcttttgtt tttttagcag tatatagata catgactcca gtagtatttt
    18481 ttacagattc taaaaggatt ttagaacttt tataagactt ttttgattgg tcttctttag
    18541 aattaatttc agtaaaggta tttttatcaa tatttctttc tacatattca tagatatgtt
    18601 ttgacctctc acttaaagag tatatcatgc tcttataagt tagtgtataa ttaaaaaaat
    18661 atacacatga ggaagatatt attacaataa ttgcagtaag tattgaaacc tgcatatcaa
    18721 ctctattgaa ttttttattt attttcatag cttaaatgtc ttgtgaaaag aacctcccac
    18781 aatctcccca taattaatat atatctataa atttcaccat aatatattca tatattatca
    18841 aatttgtgtg gaaattacaa ttagtaaaca tgcttaaagc attcaaatat agttttttta
    18901 ttattatagt atactatttt atgtataaat aaaattatat ataaatcatt gatattggtt
    18961 gtttattaat ggaagatacc gtataaaata ttctaattgg ttacgatatg tatacttaat
    19021 tgaagttaag ttaagggtta gaatatgtat tgatgaaatg gctagattta tattcataag
    19081 tattaatttt atcatagata ggtaaaatac tgtatcttaa acataagtat gattgagatg
    19141 caatcctgag atatgataat ataaattgaa ggatagtgaa ctcaatcaaa taaaatgatt
    19201 aatctagcta tataagcaaa taaatttaat ataaaagagg tggaaaatga aagacagact
    19261 taatttaaca gaaggaagaa ttacagaaaa attacttaag ctatcacttc caataatggg
    19321 gacttcattt atacagatgg ggtataacat gatagatatg atatgggttg gtaaagccgg
    19381 aagtaaagca gtagctgcag ttggaacagc tggttttttt ccatggcttg caatggcatt
    19441 tattatgatt tcaaaagtag gtggagagat aaaagtagca caaagtattg gtgcaaataa
    19501 tataagcact actaaatcat atatgaagtc agcaatagaa ataaatatta tactagcaat
    19561 aatatataca atttctttaa tagtacttaa taaacaattg ataggttttt ttagattagg
    19621 agacttagaa gttataacca tgtctagaca gtatttgata atagtagctc taggtatggt
    19681 attttatttt attaatccag tatttactgc aattttcaat ggtcttggaa atagtaaaac
    19741 tccttttcgt attaatacag taggattaat aactaatatt atacttgacc ctatattaat
    19801 ttttggatgg ggatttgctc caaaacttgg tgttgcagga gctgctattg caactgtatt
    19861 tgctcagata gtagttacta catgttttat atatataata gttaaaagta aagaagaata
    19921 ttttaaatta agactattta aagaaataga gactaaatat tataaagttc tgtataaatt
    19981 gggattacct atagcaatac aaagtggtat gtttacagta ttctcaatgc tattaggagt
    20041 aatagtagca tcatgggggc ctgtggctgt tgcagtacaa aaagtaggct cacaaataga
    20101 agcaatttcc tggatgacgg ctgaagggct atcagttgca ttaggcagtt ttgttggaca
    20161 aaattatggt gccaagaagt attctagaat aaataaaggt tgcaaaatag ctataactgt
    20221 atcttctgta cttggtataa taactacttt agtattagtg tttgcaggag agagtatatt
    20281 ttctattttt atagatgaaa gtgaggcaat agaaaaagga gcagtttatc ttaaaatatt
    20341 aggctattct caatttttta tgtgtttaga aataataaca acaggagctt tcaaaggatt
    20401 agggagaacc tatatacctt ctattataat tactatactg actggtgcaa gagtaccatt
    20461 ggcttacttt atatctagac cagaaatgtt gggtctaaat ggtgtatggt ggagtataac
    20521 cttatcaagt atattaaaag gtatattaat gataagtcta tttatatctt tattaaaact
    20581 cggaaagttg tacaagattt ctgaataaaa tttaaattat cttaaatgta tagacatttt
    20641 ctttgtttgt atataaaatt atcttattat ataaaagatt taataaggag tgaattaaat
    20701 gaaagagcca atttataaag ttatagaaaa tcatgttaga gagttaataa attcagacag
    20761 tttgaaagaa ggggatttaa tcccttctga aaaacagctg agtgaagaat ttaatgtaac
    20821 tagaatgact gtaaggtctg cacttaataa tctagttaaa gaaggctata taactagaca
    20881 aagaggtgta ggtagtatag ttattgcaaa taatatatat gataatatat cgtctgtaag
    20941 tggatttact aaagagatgg aaagtaaagg ctataaagta tctaatatat tggtatctct
    21001 tgaaatagtt caggcagatg aaaatttatc aagtaagttg aatataagtt tagaagaaaa
    21061 tgtttgggaa ataaaaagag taagattagc caatgatgca agagtttcat atatgattac
    21121 ttatatgcca gttaagttat ttccaaattt aaataagact cattgtgaaa attctcttta
    21181 taattttgtt gaagaagtgt gtgaatacaa gatagccatg tcagagagag aagtacaagc
    21241 tgtaatatcg aatgaagagt gtatggataa tctaaaatta gaagaaccag agccactttt
    21301 atatataagc caaatttgta agttacaaaa tagtgagatt tttgagtact cacacacata
    21361 tcactatgga tatacattaa ctttgaatgc tgttgtcgaa taaaatttaa ataaaatgaa
    21421 aaagttttct tgaaatgtat atacatttgg tatataataa tatcaagaat taaatgtata
    21481 tacatttaaa aataagatat atacattaag aaaaaattaa tagaaaaaca tattttaaat
    21541 gtatagttta aaaaacttat gacttaaaaa atatttaatg aatctaattt ggaggggaaa
    21601 aaatgataaa aataatgtta gcttgttcag caggaatgtc aactagttta ttagttacaa
    21661 aaatggagga tgcagcaaag gaaaacggta tagaagcaaa aatatgggct atatcagaag
    21721 tgaacttaaa aaatgaaata gaaaattgtg atgtcttact tttagggcct caagttagat
    21781 atgtattagg aaaagcaact gaaatggcaa aaccatataa tattccagta gaagttataa
    21841 atatgatgga ttatggaaga tgtaatggaa aagctgtgtt agatagagct gtagagttaa
    21901 atagttcaaa ataaagttgt actggaggat gtaaaatgga aaaattcatg tcatttatgg
    21961 ataaatatat agtgcctgta gctgctaaaa taggagctca aaggcactta gtagcagtaa
    22021 gagatgcatt tatagtaatg atacctataa ctatggtagg tgcattggga acattgataa
    22081 ataacttacc attggaagca tacaaaaatt tgatggcaag tatatttgga gaaaactgga
    22141 ccacatttgg aggcgacctt tggtggggag caataggtac aatggcagta ttcttagtaa
    22201 taggtgttgc ttattttcta gcaaaatctt atgagagtga tgggttacaa tctgggctta
    22261 tagctttatc tatctttttt ataatggctc cacaaattgg taaaatagtt cctgagggag
    22321 gaactacagt agttgaagga tggggaatga tacaacaaac ctacttaggt acagcagctt
    22381 tattctcttc tatattaata ggattattat caactgagat atttgtaaga ttatctaagg
    22441 taaagaaatt aactataaaa atgccagatg gagttccacc agcagtttca agatcatttg
    22501 caaagttaat accaggaatg ttaactataa tgatatttac tgtaatagga atatttataa
    22561 aaatgctttc taatggaagt ttcttaacag atattttaaa tacttattta ggagcaccac
    22621 tatcaaatgt agctgatagt ctaggttcta caatgcttat tgcatttata attcatatac
    22681 tttggactgt tggacttcat ggtgcaaata tagcacttcc ttttacagaa actatactta
    22741 tgaaattagg tggagaaaat gctgccttgg ctcaagcagg agcaacggaa ggataccatg
    22801 tacttgcagg tgcattcttt gatgcatttg tatatttagg tggttctgga atggtattgg
    22861 gattaatagt agctttatta atagctggaa gaagacgtaa agagatgata gtattaggtg
    22921 gtccacctgc aatatttaac ataggagaac cattgatatt tggacttcca atagttttaa
    22981 atcctatatt tatgattcca tttgtacttg caccagtaat atgtagtgct gtatcatact
    23041 tagcaataga ttttggatta gtagcaccag taattttacc taaaatacct tgggtaacac
    23101 ctcctatatt aggtggagca atggctacag gtgactggac tggcggagct ttagcactat
    23161 ttaatttaat attatcaata ttaatatata ttccatttgt catagcgtct gaaaaaatgg
    23221 aagctaataa attgaaaatt aacaactagg tagttttatt tcggtaaata aatgtataga
    23281 gttttaaata aatgtatggg gttttgtaga gtatattaaa ttataggtaa ggatggtata
    23341 atgagatgaa aaagggacta aaaatagtta caattggagg aggttcaagt tatactcctg
    23401 agcttgtaga gggttttata aatagatatg aagagttacc tgtaaaggaa ttatggcttg
    23461 tagatataga agctggaaaa gaaaaattag agatagttgg aaatctagct aagaggatgg
    23521 taaaaaaagc tggagtagat atgaaaataa atcttacttt agatagaaga gaagctctaa
    23581 gagatgcaga ctttgtgaca acacaactta gagtaggtct tttagatgcg agaataaaag
    23641 atgaaactat tcctttatct catggagtta tggggcagga aactaatggt gctggaggtt
    23701 tatttaaagc ccttcgcaca ataccagtta tatttgatat aataaaagat gtggaagaat
    23761 tatgtccaaa tgcatggatg gtgaatttta caaatccaac aggaataata acagaggctg
    23821 tattcaaata tactaatttt agaagatata taggtctatg caacgtgcca attcatttaa
    23881 aaaatgatgt tgccaaacta tttaatgtag aaagtgacag aataagtatg gattttgcag
    23941 gtcttaatca tatggtttat ggtctaaatg tatctttaga tggagaagat gttacaaaag
    24001 aagcaattga taaatttgtc aaagcagata taagtatgca aaatataaag gcaattgatt
    24061 ttaatgctga atttgtaaaa tctttgggtg caataccttg tccataccat agatactact
    24121 ataaaactaa agaaatgctt gaggatgagt tgagagagtt taaagaggga aaagctagag
    24181 gtcaagtagt taaagaattg gaagaacaat tatttgaatt atataaggat gaaaaattag
    24241 atgtaaaacc acctcaactt gaaaaaagag gaggggctta ctatagtgat gctgcttgta
    24301 atttaataag ttctatatac aatgacaaaa aagatatcca agtagttaat acattaaata
    24361 agggttctat aagagatttt aaagatgaac aagcagtaga agtaagtagt gtaataacaa
    24421 aaaatggtcc aaaaccaata agtataggat atttaccaga ttctgtgcat ggattagtaa
    24481 gtcaaatcaa atcatttgaa gtattggcag ctaaagcagc tgtatatggc gattatgaat
    24541 ctgctctttt ggcactttgt ataaacccat tgattccatc tgatgactta gcaaaaacta
    24601 tattagacga aatgttggaa gctcataaag attatcttcc tagatttaat agatagttgt
    24661 ctatagaaag taggttatgg tatgactaaa attataataa atgcagatga ttttggatat
    24721 tgtgaagctg tgaactatgg aataatttca gctcataata atggtatagt taggtctact
    24781 tctatgatgg caaatatgcc tggggtagaa catggagtag gcttacttaa agaaaataaa
    24841 actttaaatt gtggagttca tatgacttta agttgtggta gaccattatt atctaactta
    24901 aaaactattg ttgataaaga cggttttttt attaggagga ttacagacga aattattgaa
    24961 aaaatggatt gtgatgagat ttatagagaa ctttgtgctc aaatagatag ggtaaaaggg
    25021 cttggaatag atatatctca tttagatagt caccatcata tccatacttt agtaagttta
    25081 aagccagtaa tagagaagat tgtaaccaag tataatcttc caataagagg tggatttgaa
    25141 tataatttag agtattctaa agtagttcct ttaatagata gtttttataa ggaaaatgta
    25201 agtgaagaat attttataaa aaatatagac gaaataatga agtatgatgt agtggatatt
    25261 atgtctcacc cagctttttt agatgattat attttaaatt ctacatctta tgctattgat
    25321 agaacgaaag agcacaagat acttacatct aaaaaagtca aagaattttt agaaaagaat
    25381 ggattagtca tatcaagcta tagagatatt taggaggtcg aataaatgga tgagaagatg
    25441 atagagatat cttttggaat aattggattt gcaggtgatg cgaaagggct agcatttgaa
    25501 gcaataaaag aagcaaagag cgggaatata gataaagcta gagaatgtat tgaaaagtcg
    25561 aaagaatcaa ttcataaagc tcataaattc caaacagaat tgatacaaaa tgaagctaat
    25621 ggtaataaaa ctgaaataag tgttatactt attcatgcac aagaccattt aatgacagct
    25681 atgaattttc aacaattagc agaagaattt atagatgtat atgaaagatt agaaagtaag
    25741 taatttaaaa ttattattaa aaaagagtgt ataaaaataa tttttataat tattaaatgc
    25801 actctttttt tatttaagta gagtttagca atatagtatt atgttattga tactttagaa
    25861 tttagacttc tcataattgt aaggtatact agtaccaaca actacatctt caattttttc
    25921 aacaataagc caatcatcca tatttccttg atggtcaaaa tcaagaggtg ttatttcttc
    25981 aacattttca aattcaacta agcataaaca ttttttatgc caacgaactt tttgcttttc
    26041 agataaattt aattttggtt gattttcatt taaaatttta gaaatttcat cttctgttaa
    26101 tttaacatag ttttctacct ttttaacagt ggcttttgca gatatttttg cagttccttt
    26161 ttccataaaa taaagtaact catcttcaaa tactctacta tgtggtattt ttctaccagc
    26221 agcacctcta ataaccattg tttttgttcc atccaagatt ttatctaaga ccttttctcc
    26281 tttttttcct gcattatcac aatatactaa atgtaccatg ttttgaatcc tccctactaa
    26341 attccttatc tataaattgc attttatcat tgtttaactg aaaagtcatt gtatttgtgt
    26401 ccaattctta aaaaaaatac tgtttaatat aagaaaacct tatctaagct atatataatt
    26461 aagattaatt aggaattttt atccttttac aaaataatat tgactaaaaa tagaaaaatg
    26521 ctataataaa tatgtgctta tgataatcaa tatcatgtaa gtataataaa caagtaggag
    26581 aagtaatcat gaaaaaaata aaatcacttg caatatttat atctattata actacgttag
    26641 tacttgttac agcatgttca gataagaata cagaggataa agataaatca gagacaagag
    26701 ttgtacaatc tgttaaagga gaggttaaga taccatcaaa tcctaaaaaa atagttgata
    26761 tatcaggaag tagtgaagaa ctattattag caggttataa gcctgttgca acagcaaatg
    26821 tagactcata tgaaactgat aaattaccaa gttacataag agaagagctt aaaggtgtaa
    26881 agatagttgg gcactcaatg atggatacta tggatatgga agctatatta gaagtaaatc
    26941 ctgatttaat aataatgagt caaagacaag aaaaaatata tgaccaatta aaagaaatag
    27001 ctcctgtagt tatgatgaaa gattatgcaa atgactggag aagcaagtta actgatgttt
    27061 caaagttatt tgacaaagaa gaagaagata aaagttggct acagaagtat gatgaaaaag
    27121 ctacaaagtt aggtaaggaa gttatagaaa agaatggaga aaaaacttat ttaccagtgt
    27181 tggcaagttc aggtcaattt atggtattta gtgatggtgg aataggtact ctaatcaatg
    27241 atgatatgaa attagctaga cctaagaata tgccaaaaca ggatggaata acactaccaa
    27301 tggtaagtat ggaaggttta acagatatag atgcagacca tatagttgta attgctacag
    27361 aagcagataa aaaagattta gaaaatagtg ctatctgggc tcaaataaga gcagtaaaag
    27421 atggtaatgt aacaatactt gatgctgctc catttttcag tcaatcatac aatccaattg
    27481 gaaaagagtt attattagaa tcagttaaaa atgaattaac aaagtaattc ttaacttagt
    27541 aggtgtgaga taatgatatt catttttcac acctattttt aataaatctt aaaattaaaa
    27601 tacttaatag atgatattat actgacgatt aaaagggaaa aggaggtagg ataattgact
    27661 aagctgagta aaaaaaatat aacttatttg ttgatattag taagtatagt tgtacttgta
    27721 tttggaattg tattatccat aactattggg gcaaaagata tgaatctatc aactgttata
    27781 gatagtttga taaaaatgga agatggaata aatatgagaa tagtaaagga tgttagactt
    27841 ccaagggcaa tagcagctgc acttgttgga gggtttttag cagtttctgg ggcaataatg
    27901 caaggaataa cgagaaatcc tatagctgaa ccatctgtta taggaattac acaaggagct
    27961 acattcgcaa tttcgatatc actggtactt caaaaaaaac ttcctcaact tatacatgga
    28021 agttttagtg taatgatgtt tgcatttatt ggagcaagta taagtggatt atttatatat
    28081 tttataagtt ctaaatcaag aggaagagtt aataatgtaa aattagctct tgcaggagtc
    28141 gctcttggta cattgctaat ttctttggca tcagcaatat ctatgtattt taacctatct
    28201 caacaattaa gtttctggat atcaggaggg cttgtaggag tgaagtggga aggtataaaa
    28261 ttgctatttg tagctggtgg tattggattt attttagcta ttattatggc tccaagaata
    28321 actatattaa gtcttggaga agaagtggca ataggattag gacaaaaaac taagtttgtt
    28381 agatttatat gtatagtact tgtaatatta atgactggag catctgtgtc agtgtctggt
    28441 aatattattt ttataggtct tatagttcct caaatagcta aaggaatagt aggttcagat
    28501 tataagtata taataccgag ctctttagta ttaggagctg tattgcttgt atatacagat
    28561 atattaagta ggatgataaa tcctccatat gagacaccag taggttctat aacagcactt
    28621 ataggagtgc caatatttat ataccttgtt agaaaggggg agaaataggt actatgaaaa
    28681 atattataaa aataaattct aaaacattac ttgttatatc aattttaatg gtgcttattt
    28741 ttatcacttt tttattgagt ttaaatatgg gctcattttc tatagaacca atggatgtta
    28801 taaagacttt tttagggcag ggtcagcgta atcatgaaat tgcaatattt aaattaagat
    28861 taccaagaat agtaatagca cttttggttg gttctgcatt atcaacagca ggtgtaatac
    28921 ttcaaggagt tacaaagaat gatttagctg attctggaat tttgggaata aattcaggtg
    28981 ctgcattgtt tgtagtagtt tatatatacc ttatgaatgg taatgtatat gaaggtatga
    29041 gtaacttgac tgtatttaca atgcctattg ttgcacttat aggagcttta tttggagcat
    29101 ttcttatata ttctcttgca tggaaaggtg gtataaattc gtcaagatta ctacttattg
    29161 gtataggtgt aaacatagct tttacttcaa ttttgacgat attccaattg aaatttacaa
    29221 cacaagaatt taatagggtt atggcatgga catcaggaag catttgggga acaagttgga
    29281 aatatgtaat agctgtgctt ccatttatag tgatttttat gggtataact atttataaat
    29341 ctaaatatat agatgtttta aatttgggtg atgaagtatc tataagtctt ggtgtagatg
    29401 tagaaaaaca aagaagaaga cttataatat atgcagtaat tttatctggt gtatcgacag
    29461 cagtagcagg tagtatttca tttttaggtt taatagctcc acatataggt agaaaaataa
    29521 taggaccaaa gcataaaaga ttaataccag tatcagcatt gataggaaca ttattacttt
    29581 taatagcaga tactatatca agaaatcttc tagcacctat agaaatacca gtaggtatag
    29641 tagtttctat aataggagtg ccgtacttta tttatttaat gttggtaaat gattaggaaa
    29701 gggtgttgtt atgaactgta taaatactaa gaatctaaat gtatcatatg gaaacacaga
    29761 tattataaaa aatttaaatt taaatatacc aaaaggaaaa ataactacca tcataggggc
    29821 taatggttgt ggaaaatcga caatacttaa aactataggt agaattatta gccctaatag
    29881 tgggaaaata tatataaatg gagaggacat ctacaaaaag aagtctaaag aaatagcaaa
    29941 agatatggct gtacttccac aaagccctca agctcctagt ggtcttaccg tttcagaatt
    30001 aatttcttat ggaagatttc ctcataaaag tggatttggt aattctagta aagaagacag
    30061 agagattgta aattggagtt tagaagttac tggaattgca gaatttaagg atagaaatat
    30121 ggaagattta tcaggaggac aaagacaaag ggcatggata gctatggctt tggcacaaga
    30181 aactgatata ttattactgg atgaacctac aacatattta gatttggcac atcaattgga
    30241 gatactaaaa ttattagatg aactaaataa aaaacaagga agaactattg tcatggtaat
    30301 acatgaactt aataatgcag caagatttgc tgaccacatg ataggtatta agaaaggtaa
    30361 aatagtttgt gaaggtgatg catatgatgt tatgacgaag gataatctaa aagaattatt
    30421 taatattgat gcagaaatag caacagaccc aagaacaaat aaaccaattt gtataactta
    30481 tgacatggtg taaatggtga caacatggag aatcaagaag cattaagaca tgaaaaaata
    30541 tggattttat tatttaggta ttcgatacct gcaataatag caatgatggt aacttcactt
    30601 tataatgtag tagatagagc ttttattggt tctatggaag gtattggctc tatagctatt
    30661 gcaggtcttg gtgtaactat gccagtattt actctaataa tagcttttgg aatgttggta
    30721 tcagtaggtg ctagcacaag attgtctata aagttagggg aaagaaatag agaagaagca
    30781 gagaagatat taggtaatgc tttgacatta tctataatta tctctttaat tataactata
    30841 ttaggattag ttttcttaga agagatactt tttattttgg gtgcaagtaa agattcaata
    30901 ttttatgcaa aagactatat gagtgtcata ttggttggaa gtatatttaa tttagttgca
    30961 ttttctctta ataatgcaat tagggcagaa ggtaatccaa aattagcagc aaggacaatg
    31021 attgtaggat gtgtattaaa cctgatattg gaccctatat ttatatttgt atttaattta
    31081 ggtataaaag gagcagctat agcaacagta ctctgtcaaa tagtagtatt tttttgggta
    31141 atacattatt ttataagagg gaagtccaat ttaaaactaa aaaaatgtaa cttaaaattg
    31201 aataaagata tagtaaagaa ggtatttgca ataggaatga caccttttgc tatggaagta
    31261 gctataagta taactcacat gtttacaaat aattctctaa aggtttatgg tggagattta
    31321 gctattggag ctatgacagc acttacatct attttattga tgtttatgat gcctgtgttt
    31381 ggattgaatc aaggtatgca aactataata tcatacaatt atggtgcaaa acaatatgag
    31441 cgtgcaaaga aaactttaat attatctatc atagtgtcag ttgtcatatt gtcatttgga
    31501 tttttagtag tacaagtttt cccagaagta tttgtaggta tatttaataa agattcagat
    31561 ttgatggata tagcagtaag aggtataagc ctaaatctaa ttacattgcc tataatgggg
    31621 atttctattg taggacctgt gtattttcag tgtataagta aagttaaaca ttcaatgttt
    31681 ttaactcttt taagacaatt tattttattt ataccattaa tcattgtact tccaattcaa
    31741 tttaatttag atggtgtttg gttggcacag ccagttgcag attttattgc tatgataatc
    31801 gtattattat tcttaaaaag ggaatttaaa acaagccgag tgtaagaaat ttagaaaata
    31861 aaattaaatt ggaaaataaa aagacttgtc tttataaaat gattaaaatt attttataga
    31921 gacaagtttt ttattttatt taaacggaac tatccatact ggtttcttct agtttttttc
    31981 caaaagtcat tttctcaaat atttcttgag gtagaggttt tgaaaaaaca tatccttgta
    32041 tcatatcaca attaattttt ttaagataat ccatttgcaa gattgtttca acaccttctg
    32101 atatactatt catatttaat ttttttgcca aattaactat agattctatt acatgatttt
    32161 cagcaatatt atctgcatta ggtgagctaa aaaaagcacg gtcaagtttt aatgtgtcaa
    32221 cttttatttc ttttaacata ttgagtgaag agtatccact tccaaagtca tctagtgaac
    32281 attgaaaacc ttcttcatgg atttggtcta ttatattaat taatttttgg agattttcaa
    32341 atacaagtgt ttcagttaat tcaatttcta agagcttagc aggaatgttg tatttattac
    32401 gaagcattct gtatttttct aaaaaatcta tattatttaa attagcacgt gaaaaattaa
    32461 ctgaaacagg tattggagtt tctccattat ctatccattt tcttatcata ctacatactt
    32521 tttcaaaaac atagtggtcg agttttgtaa taaaaccatt tttttcaaag aaaggaataa
    32581 actcgtctgg tggtataagg cctttatttg ggtcttgcca tcttactaat gcttctgcac
    32641 ctacaatagt attatctttg aggcttattt taggctgaag atatactata aattcgttat
    32701 tatttaatgc ttcctccatt ctattttcca tttctttttc tttaatcatt tttaaacgct
    32761 ctaaatcact ataaaaaaca catgtataaa gtggatgatt tccaatgttt cctttattat
    32821 tttttcgtgc aacatttgca cggtcttgaa ttgaaactaa aggtagattt gggtcatcaa
    32881 ttttatatac acctatagat agagctataa aatatttaca ttcttcattt ttattgaaac
    32941 tattaatatc attggtgata ttttctatgt acttaagaat ttctttttga ggaatagttt
    33001 taataagtac attaaactgg tcattagaaa ctcgacaaag caattctcct ggttctagat
    33061 aattactaat gacatcatgt atgtacttta atgttttatc tcctgcttca ctaccaaaag
    33121 aatcattaat aagtttgaat ttctgaatat ttatagatac caatgaatag ctttctgatg
    33181 aagatgactg tataattttt ttagcttcaa tatcaaaacg tgctttactg taacctttag
    33241 ttacagagtc tacataggcg atttttataa gttgtgccct gtttttttga tttataaaca
    33301 taatcaatat aataagcaat aaaaatagta taacaattaa aatattgatg aagattgctt
    33361 tttttagaag taaatcaaac tgtgcacttg ctgtttttgt tggaacaatt gaaaggaggt
    33421 ataagttttc ttcttgtaat ggaagatagt gcattgcctt agaaatacca tcatttaatg
    33481 tataatacat agaaccagtt ttgttctttt ttaagtttat tttcatttct tcaagtttat
    33541 ttttatcaac ctgttttcct tggtgtttaa tcatgtcaaa aaaatttacc acattttttg
    33601 gagcattttt gtttgctgaa cttacaataa aatttccatc ttggtcgata atttgggaaa
    33661 atccttcacc atgaaagctt tctacactta ataaatttct catagtatca atagtattcc
    33721 aagcagcaac agctccaaca attttatcgc cattgtatag tggtacagaa tataaaattc
    33781 catatgtacc agattgtgat ttaacaggag taattgtttc tttgccttga agggcttttc
    33841 tataaaagtc ttgtccttta acattacctg tatctttaag ggcacttaca aaatttccat
    33901 tagaatctat aatacctaac caatcaaatt caaataattt taattttttt gataagtatc
    33961 tattgacttc tttttcacta tcattaatct caaaataagt atctcccata gaatatagtg
    34021 tcctaaatat acttttacat ttcacattaa ttgtagtgga aataccttgt gaaacttcta
    34081 caagatatcg ttctgtttca ttatgtgtta ctttatttag attcataata aaagtgacac
    34141 atgttaatga cacgattaaa agaagtgtca atagtaaagt agctattatt tttttatttt
    34201 ttgtgttttc aaagttcatt cttttgtttc atcctccatc ctttatttgt ttacaaataa
    34261 gaattctctc agacatatta taccaaatat cttttcatac aaagatatta aattttattt
    34321 atcccacttt acatttagct ttatttatgt cttcttagag attaatcaag atacgtttat
    34381 tgtttaaatc ttattttata atattttgag taaaagaggt taaaaaaaga actgttttca
    34441 aaataatttt gatacagttc cttttcagta tagaaaattt ttatagtatt agaaagaact
    34501 tttagcttat gtatctacat aagtattata tttataaaag atattttgtt acaatctaaa
    34561 atgtagatga aattctgtaa atgccaaatt ctctatgacc aagactttca gctttggtat
    34621 gtttaccatt acagacttct attatttcat taaatatttc ttgacctata tctgctattt
    34681 tagcaccatc tgttataatt ctacctgcat ttatatcgat attgtctggc attttgttgt
    34741 atgtatcact attcccagtg attttaataa ctggtgaaat agggcttcct gttggagtac
    34801 ctctaccagt tgaaaagatt acaatttgtg caccacctgc taccatacca gtgatagaat
    34861 ctatatcttg acctggagta tccataaaat ataatccttt tttatcagga ggtacaatat
    34921 cagcatattc aagagcacct ttgaatggct tattgcctgc cttatacata cacccaagtg
    34981 acttttcttc aattgttgaa agtccaccag ttttattgcc tggagtaggt tgaccactac
    35041 gtaaatcttc tcccatagca attgctcttt tttctacatc acttacaaat ttaagaaact
    35101 tatctttcat ttcttcatct tcaaaacggg tagccaacaa atgttctgca ccaattactt
    35161 ctgtagtttc acttagtatg ctacttccac cttcatctac aagaaggttt gatgcaacgc
    35221 ctattgaagg gtttgaagct attccacttg ttgggtcaga accaccacat tcaagtgcta
    35281 atgtaatttc actcatacca aattcaactc ttacttcttt tgatacttca cgagccattt
    35341 tacttactat ttcagctccc ttagaaactg tttttaatgt tccgccacat tcctgtataa
    35401 caacgtaatc tacctttttt cctgttgtag ctatttcaga tgctaattct tttgcttgaa
    35461 taccatcaca tccaagacca actactaaaa ctgcggcaac attaggattt tttccaaatc
    35521 ctattaatgt ctttgctgta agctctatat cagaaccaat ttgacaacat ccatgttgat
    35581 gagggattgc tattgctcca ggcacaagtg atgctattct tgtagctgtc tcacttgaac
    35641 atacagatgt tggaataatt aaaacatgat tacgaatacc aaactgacca ttttctctta
    35701 aataacccat taatttcatt ttaacttcct cctatttttt atctccacga ccacgtgtac
    35761 tttcaatgtt atgtacatga acatagtcac cagtttttat gtcaactgtt gcaattccta
    35821 taatttcacc gtatttgtat acaacatcac ctttttttac atcttctgta gccatcttat
    35881 gaaagactgg tatattatca tttactatgt aagattttcc atcaattgaa actttttcac
    35941 ctttaactaa aggtctgaca catgtaacta gattatcttt ttcatttgca tgaataattg
    36001 cattcattaa ttttacctcc ttaagtatta atttacttca atatttttat ttgttttaaa
    36061 aatagatttt ttcttttttt ctcttttatc tagataggaa actaacattg gacaacatat
    36121 tgctgtaaca ataatagcag cagcaacctg tactgttgaa acagctgcta ttgtagctag
    36181 agtagggtct atagctgcta aagcttcagg agtaccagct gcatttccgg ctgttgtacc
    36241 tgtagctgca cctactgctg gatgttctgc acgtataagt ttcattacaa agtacccacc
    36301 catacctgtt attatagtaa ctcctaaacc aagtacaact ccaggtagtc cagcagttat
    36361 aatttgatta aagtttaatg ctgctcctaa aggaaaagcg aagaaaggaa ttaataatgt
    36421 tgtaccaggt gcaagaaatt ctcgtatatc ttcatcaagg ttaccaagta taaatccaag
    36481 tagtattggt ataagtgctg caaatagtgc tattataggt acatttgcaa gtccagttac
    36541 tccaaaagca agcattgtaa aaaaaggacc atcatttaga gataagatag atattgctcc
    36601 aacatctgtg gagtctccat attcacctgc aagagcagca aatagacctc catttgaatt
    36661 agtcatggta gcaactatgg caagaggtgt aataccaatt atacctttag gtccaataaa
    36721 tttactaaca ataataccta atactgcacc aattataaat tttgttgctg taagtactat
    36781 acctttagtc aatggtttac cagcttgtct gatattgatt tgagctccat tgcatagaca
    36841 aaatagagca agtatactca ttgcaccagt tttaaataag gatgttgtga atcctccaat
    36901 ttcaagagct tgtggacata ctgtattaaa tagtgctccc aataacaagg gacagaccat
    36961 aagtcctcct ggtatctttt tcactgattt taagatgtgc atctagtatc actccctttc
    37021 atttttatat aggtattata aaagcaatta atatgccaat atatagagtt tgtatcttta
    37081 gttatcatga ttatttttaa taatcgattg aaatgctgta gattacttat aattaaaagt
    37141 acgattgacg agaatttcac ttacaaagat tctttttatc atataattgt attttttatt
    37201 gaaaacaaat aaacgtctta tgtattaaaa ttaaacataa aacgttttga tatatatagg
    37261 tatgtattat ttttaaacat catcttctat ttcttttaac ttacgccata gagtggagcg
    37321 agttatcttt agaatttcac aggtttttgt agtatttcta ttattttcgt tataaatttt
    37381 atagatatat tttttttcta aagtttttaa atctaaatta ctgcattcaa aatcactatt
    37441 atctttatca actatattat ttgtatattc attgctaacc ttttctaata aaatcgagtc
    37501 aaatgattcc acaataacag ccctttccat cataccttcc aattccctta tattaccttc
    37561 atattctcgt tcaagaagtg cctttttaat atttggagtg ataattaaag gcgttttatt
    37621 gtatttgctt gaatatttat gtataaaaaa ttctgataat tttataatat cttcttttct
    37681 ttcttttaat gaaggaagat ataatgttag tatatttatt ctaaaataaa ggtcttgtct
    37741 aaataaacca ttgcgcatca tattttttaa gtctttattt gaagcacaga taatttttac
    37801 atctatagga ataactttat caccaccaat tctcataact tgtttttcct gcaataccct
    37861 caataatcga ccttgaagtt caagagggat ttcacttatt tcatctagga agattgtacc
    37921 ttcatgtgct agttcgaata cacctgcttt accttttttt ctagcacctg taaatgaacc
    37981 ttcctcataa ccaaaaaact cactctctat tagagatgga ggtatggcag cacaatttac
    38041 agcaacaaaa ggtgcatttt tacgcttact atagttatgt atactttgac aaaatagttc
    38101 tttaccaact ccagattctc cagtaataat cataggagta tcataacaag catatttttt
    38161 tgcaagttct atacaatctt ttgtcttttc actagcatga attatatcat caaaagtgta
    38221 tttagcagat agacctttgc ttaataagct ccttcttatt gtatgttcaa aagaacttat
    38281 ctccttgcta tcttgaaatg ttgaaacagc cccttgaatc tgaccatcaa caatgattgg
    38341 aactctattt gtaataattt ttgtactccc tatattttgt atttcaccaa tttgaggttc
    38401 catagtctca actacttgtg gaagaactgt gtttgggata acatctacaa cattatgata
    38461 aagtgcattt tcttttttta taccaaatat tttttcagca ctcttattaa ataatgttat
    38521 tttaaaattt ttatcaactg ttattattcc atcatgtaca aaatctgtca tagcttctat
    38581 ctgtaatctt cttttttgtt catccttggt tgcttcgagt atttgttctg cttgttgaat
    38641 ggctctaagt atgttttctt ctctagattc gattaatatt cccttacaat taagtctctt
    38701 aacaatatgt gcaacagtgg tatctcctat atatgtgttt atacctttct ttctgtactt
    38761 ttctatagca tcataaattt cttcttcttt ttcaatttca atcatagtta ttttcttatt
    38821 caatatttct tctataatat cgaaaccgta gatgacatta ttaaatccaa ttattccaaa
    38881 tggttcgttg gaatttttta cctctttgta actttttata atatcataag catctacctt
    38941 aatttcaact ataggtatat tgtaagtagc ttttaacata ttgtaagttc cacctcggct
    39001 tatgataatt ctagtaccat gattaatact tttttcagca agaggtatac cttcttttag
    39061 attgccaaat acaacatcaa tatttgtata tttgtttttt ttaactatgt gaattgattt
    39121 ttcataggtt cctttagtgg gagcaataac gagtatttcc ttcataataa ttcctccata
    39181 tttcatcaaa taaacttaaa tattatctta tgactaaatt ttatcagtta tattttaaca
    39241 ttttacttta tatttaatta taaataaagt atttttaaaa ggaacattat aaaagactgt
    39301 atcaaagtta acttttagaa ttataaagtt tcatcttttt acagtctttt aatatataat
    39361 atctatttat caaatctatc tactttaaat aatttcatat ttttattttg tttgccaaga
    39421 tataattcac ttaacattat acctcctaat attgcaaaga gtataccatt tgctccataa
    39481 cctaagcaat accatagatt gttattttta ttatctggac caataaaacc taaattatct
    39541 aaagttgaag caaaacaacc acaatattta tattcaactt caatgtcttt tatatcctta
    39601 aacatacttt tcaatctttg ttctaaaata tcatactttt cattggctaa agtttcattt
    39661 tctatatcat caaaacttac atcttcacca cctataatta atcgattgtc tttagtagtt
    39721 cttagataat tatatgggtc acagttatct ctaattaaaa tgttgttttt ccaagaagct
    39781 atgtttttaa gtggtttcgt tgctatatta aaagtatttg acttagttgc aaaatttctt
    39841 tttgtaaata aacttgtatt gtaccctgta gctacaatta attttttacc atgaactttg
    39901 tatccatacg atacttcagc agtaacctta tcatttgata aatctacttt ttttacttct
    39961 gtattttcat atacttgaag accatttttt aaacttacat caatcaaatg gtgactatat
    40021 ttatatgggt ctaattctcg tcctccattc tttgctatca atcctgattt taaatcaaag
    40081 ttaaaagggt ttgtggattc atcaatatat tcaacatcaa atccattttc ttttcttaag
    40141 ttatattctt ctttgatagc cttaacttca agtttgttgg cagtataaag tagagtatct
    40201 cttttggcat aatcacactt atttccatat agctctataa atgtatctaa ttcttcaagt
    40261 gctgaagtac aaaggttata tgcttttaga gcatctttta gagtcataac ctctgttaaa
    40321 tctatcaaat tgtcatctaa ttcatactgt aatagagaag ttgtcacgct agtgcttcca
    40381 tgtgcaatcc ttcctttttc aagaatgaca gactttatat tgtttttagc tagatagtag
    40441 gcacaaatac atccagttac gccaccacca acaattataa catcagtatc aatatcatca
    40501 gtaaggtatg gaaattgtct tggaacttta ttaatattgg taaaaatagg atttcctttt
    40561 acatattctt gattcatata cttcactcct aaaatttatt atgtatgagt gtattatttt
    40621 ctatagcaaa taatattata cattttaatt atctagttat atgggtatgt atagataaaa
    40681 tgtgataaca ttttagtata aaacatatgt ataatatatt cataattacc ttattttaag
    40741 taatatagta tataatgttt gttaacaagt aaaaagattg aataaaagtt aattaaaaat
    40801 ttaaagtagg aggtaaattt atgctttcaa aaaatatagc ttctaaggta ttagaaaaat
    40861 gtctaattac tggaggagat tttgctgaga tttttgaaga agacactata aataattcta
    40921 ttagtttaat agataataaa gtagaaaatg caataggtgg aagaaattat ggtataggaa
    40981 taagaatatt taaaggattg aaaagtatat atgcttatac aagtgacaat tcattaaata
    41041 gtctgttgga tgtagcatac aaagctgctg ttgctttagg taaattggaa gatggaaaaa
    41101 gtgtaatatt aaatgacagt attaaaataa ataacataca taatataaaa atttatccaa
    41161 attcaatagg aaataaagat aaagtaagtg ttatgaaggt tgcatataag agtgcaaaag
    41221 aatttagtaa tgatatatct caagtaagtg ttagctattt ggataaagac caaaaaatat
    41281 taattgcaaa cactgaaggt atatatgttg aggatagaag aataagaacc agactaggga
    41341 taagttcaat tgcatctaag ggtaatgaaa atcaaactgg atttgaaggt cctgggggtt
    41401 gtaaagggtt tgaaatattt gaagaaatag acccagaata ttatgcaaaa gaatcagcta
    41461 gagtagcgca tactatgttg catgctaaaa attgtcctgc aggtaatatg atggtagcaa
    41521 tagataatgg atttggtgga gtaatatttc atgaagcttg tggacattct ttggaagcta
    41581 catcagttgc aaaggggaac tctgtatttg cagataaatt aggtcaacag attgcttcca
    41641 caaagattac agctatagat gatggtacaa taccaaacta ctggggttct atgaatatag
    41701 atgatgaagg aaatccaact caaaagaata tactgattga aaatggaatt ttgaagtctt
    41761 atatgataga taaacttaat ggtagacgaa tgggaatgaa tcctacagga agttctcgta
    41821 gacagaacta caaatttgca ccaacttcaa ggatgactaa cacttatatt gctgctggag
    41881 aagatagacc agaagatatt ataaagtcaa taccagatgg actttatgct aaaaaaatgg
    41941 gtggtggttc tgtaaatcct gtaacaggag agtttaattt tgcagtttca gaaggttact
    42001 taataaaaaa tggagaaata caagagccag ttagaggtgc tagtttaatt ggaaaaggta
    42061 gcgatatact tatgaatata gatatggttg ggaataacgt aaaacaagct caggggatgt
    42121 gtggctcatc atcaggaagt ataccaacta atgtaggcca acctatgata agggtaaaag
    42181 aaattactgt aggtggaaga taggagggat aattgtggaa cttaaaaatt ttaaagatat
    42241 attatttaaa aaggctctaa gtgaaggttt tgaagagtat gaaatatatt attatacagg
    42301 agaaaattta agtataaata tatatgaagg agaagttgag aaatacaatc ttgataaatc
    42361 ttttggttta tcttttagag gtaaggtaaa tggaaagata ggttattctt atacagaaat
    42421 tttagatgat aaagctgttg atatgttgat aaaaaatgta aaagatggag taaacactat
    42481 tgaaaatgaa gatgtacaat ttatatatga aggagataag cactataatg atgtaaagac
    42541 ttattctaaa gagctagaaa atttagaggc agataagttg attgatttag ctttagaaat
    42601 ggaaagagag actaaagctt attcagataa ggtggtaaat ttatctaaat gtactatatc
    42661 ttattctgta tcaagtaatg gtatatctaa tactaaaggt cttaatttaa gcaataaaac
    42721 taatatgctt atagggtttg tagttcctat catagaagac aatggacaaa aatatgatgg
    42781 aataggatat aatatagcaa attctattga agaaataaaa ccttgtgaga tagcaaaact
    42841 tggtgttgat aatgctttat ctaaagtagg tggtaagagt attccatcag gtaaatataa
    42901 aactatattg cttaatgaag ctatggtatc tttgcttagc acattttctg ggatatttaa
    42961 tgcagattca gctcaaaaag gattatcttt attgaaaaat agagaaggag acatgatagc
    43021 atctcctata gttacaatag ttgatgaccc acttttagaa aatggtatgg catctactcc
    43081 ttttgatgat gaaggagtag ctacatttaa aaaagaagtt gttttaaatg gaaagcttat
    43141 aactttactt cataacttaa aaacggctaa taaggcaggt gtaaagacta caggaaatgg
    43201 aataaaatct tcatattcat cacctataag catatatcca actaattttt atatagagaa
    43261 aggagataaa tctttagatg aaattataaa ggatatagat gaaggattga tggttactag
    43321 ctttgcagga cttcattcag gtgcaaattc agtaacagga gacttttctt tagctgccaa
    43381 aggcttttat atcaaagaag gaaaaaaagt atttccagta gagcaaatta cagtagcagg
    43441 aaactatttt gacctgttga aagatattga agctataggg gaagatttag aatttccaat
    43501 gagtagtata ggttcacctt cagttgttat taaagagcta tcagtagctg gaaaagatga
    43561 ataattaaaa agtaattttg tggataaaag gtcatgttaa ttttaattaa tatggctttt
    43621 tattatttaa gtagatttta ttatctaagt tatatgaaaa agtcgtgatg catacaatta
    43681 atatcatgta ttaaatttaa aggaggagat attatgagtg atgcacatta tgacatgcac
    43741 aagcgaaatg gatattcaag tgatgagcca tatccagaga taaaagtttt aggtccaaat
    43801 aagtattatg cagaattatt gatggatgac tatgccggag tatcaagtga atttacgagt
    43861 gtaaatcaat atctatacca taattttgat ttagatgaaa cgcatagaga gttaagtgaa
    43921 atgtggataa atatatctat aacagaaatg ttacatatgg agatattagc aaagactata
    43981 agattattgg gtggaaatcc tgtatataga ggttctacaa gttcttgtgg tgcatattgg
    44041 aatggtggtt ttgtatgtta tggaaattct atttgtaaca gattaaaact agatttgcat
    44101 ttggagcatg tggctattaa taattattat aaagatataa gtcttattga agacccttat
    44161 ataaaagcta tattaaatag aataatccta gatgaaaaac ttcatgtaag tttatttgaa
    44221 aaggcaatag agaagtattg taaataaatt tgaaaattta gttattcatc attttattca
    44281 tatatataaa ataaccatca tacattttct tgaagggagt tgctgttgat atgtattatg
    44341 tatatgtgaa tgatataaac atagcagtat atgatttgaa tccgagtgct aaaaaaactg
    44401 tactttttat acatggttgg cccttaggac ataagatatt tgaatatcaa acaaatatat
    44461 tgccaaaact cggatataga acagtttcaa ttgatttaag aggttttggt aaatctgatg
    44521 caacatcagg aggatatact tatagccaat tagcagacga tatttataag gtggtacatg
    44581 ctattggatt aaaagacttt acccttgttg gtttttcaat gggaggagca atcgtactta
    44641 ggtatatgag tttatttaat ggatatggag tgtcaaaatt ggtattagct gcagctgctg
    44701 caccatcatt tgtacaaaga cctccagaat ttccatatgg tatgacacgt gaagatgtaa
    44761 ataaattgat agcacaagca tgtactgata gaccagaaat ggtaaccgat tttggcgaaa
    44821 aagtatttgc atcaaatcca ccagaaagct ttagaagatg gtttaatgat attggtttta
    44881 gtgcatcagg tattggcact attggaactg ctgtatcttt aagagatgaa gaattattta
    44941 atgatttaaa atgtgtaaga gtgcctactg gtatatttca tgggaaatta gatgaaatat
    45001 gtccgtatga atttgcagtt tttatgaatg aaaaaataga agattcaatt ttatatactt
    45061 ttgagtatag tggtcatgct atattctatg atgagcttaa actatttaat cagaaatttt
    45121 tacagttttt agaggaatag ataaatttta ttatcactta gaaaaagagt aatattatgt
    45181 gaaaagattt aagctaaatt ttatgatgtt ttttacacta aacaaatagg gttttagaac
    45241 ttgtaactaa gttctgagac cctattatta tatattccta aaatttgtta taatttattc
    45301 cttgtcattc ttaaaaatgt attaatatat taacgaattt atattaaatt tttgtttata
    45361 ttccaataat gtcaaactaa ccgttttaga aattaaatta tatgtgaaaa aagatagctt
    45421 acattatttt attatggaaa ataatagtaa atggtacaaa atttgatttt taagatttaa
    45481 aactttttta aaaagtgcta caatagacca aattattact ttctatactc gttaaacagg
    45541 aggtgggact atgaaaaaac ataatatttt atttgtatca actgatgaca aaataaatat
    45601 agatatatca aaacaattgg aaaatatatt tggagaattt tgtaatatag ataacttggt
    45661 atatgtaaat aggataaata ttgaactgtc aagctatgag cttgtagtat gttcagacaa
    45721 tgatataaag gaatatatac ataataatat tgataaaaat atacctattg taatagtaca
    45781 tcgtactata aatattgaaa atataaatca gataataagt atagaaaatg attctgatgt
    45841 tatggttata gatgcttata aagaatcagc agatgaaact gccaagataa ttagaaaact
    45901 aggattaatt catattaatc taataccata ttatccaggt tgtgataaat ctaaatgtga
    45961 gattggaatt attacgggaa gcagaaacag cataccacaa aacataaagc aaataattga
    46021 cataggtgat aaggtaattg atataaatac agttatagaa atctttacaa aactaaatat
    46081 atctatagat aaactacata ttattaagga aaaatacaat gaagatacag taagtggata
    46141 taggtattat acaactatga ataaaaccat gaagagtttt ttggagatta tagatgaagg
    46201 tattgcttct gttgataaat taggaaaatt tatatattgc aacaaagtat tttctaatct
    46261 agttggaata gaccaaaatg aaattatatc taataacttt atggacttat ttagtgataa
    46321 ggttgtcaaa aaaatatttt ttcaagaaga tgaagttaat gatgaagtag taaatttaaa
    46381 taacaaaaaa ctgataatta ataaagtaaa tgtttatgaa aataatgaac gaataaagag
    46441 tattataagc attaaaaata taagtgcaat tcaagtgctt gaggacaaga ttcaaaataa
    46501 acttcagtca aaaggttttg tatcaaagta tacatttgag agtgttgtag gtgagagtaa
    46561 aataataaaa gaaaaaatta atattgcaag aaaaatagca actacagact tttctgtgtt
    46621 gatacttgga gaaaatggaa caggaaaaga aatatttgcc caggcaatac ataatgaatc
    46681 tctaagaaaa aacaagccat ttgttgcagt taatctatct tctttgtcag atacacttat
    46741 tgaaagtgaa ctttttggct atgatgaagg aagttttaca ggagcaataa aaggtggaaa
    46801 aatgggtata tttgaaagag cacatacagg aacaattttt ttagatgaga taggtgatat
    46861 atctttagat gtacagcaga gattgctaag agtattacag gaaaaagaag ttatgagaat
    46921 gggcggaagt aaaattatac caatagatgt tagaattata gctgcaacaa ataaagattt
    46981 aaagaaaaaa attaaagaag gttcttttag agaagatttg tattatagga ttaatgtatt
    47041 acatatagag atacctagac ttagagaacg taaggaagat atacctctta taagtaagta
    47101 ttttttagat gaaataaata gcaacaaatg ttttacagag gaatcaatgc aagctttaac
    47161 attgtatgaa tggccaggaa atgtaagaga gcttaaaaat ttaatttatt atattgatac
    47221 tatagttgag gaagatagag tagattacga gcatttgcca gaacaattta gatttgaaaa
    47281 aaacaatact ttagttaatg aaaatttcga ttcaattatc ttagatttca aacaatctaa
    47341 tttctttgag gaaagtatat gtatattgac cagtatagaa acttggaata ataaaaatat
    47401 attattagga agaaataaac tgcaagagat tttaaaagaa aaagatatag ttttaagtgt
    47461 agaccaaatt agaaaaagaa tagataagtt aaagagccat ggtttacttt tatctggagt
    47521 aaaaaaacaa ggtagtttta taactgatga aggaaagaac tttatatcat atgtaaaaat
    47581 taagggagtg atatagggga ctaaaaaggc aaaacaccct aaaaaaatcc ctataatgga
    47641 tagaaataaa taaaattatc tttaagatta agataattca aaaatattga ataaataatc
    47701 taagaagatt atttttaata aaacagtagt aaatatcaac cttactactg tttttatttt
    47761 ttgcaagatt tattatacaa ttaaaattta tattttggca catcaattgc tacataggaa
    47821 aaatataaaa aattgtagaa cttggaggat gttgttatga agtcagctta caaaggatat
    47881 gaagcctata gttatttaga aaaaggaaaa gatatttcat ctattgagat gtgtaaagga
    47941 gataaaagag ttaaagaata ccttattgaa ttagatgata ttcaagaagc taaggttaaa
    48001 agtatagtgg atgaaaaaat atttatatca ttacatgaac atccagtatt atttccagaa
    48061 cacctagaaa gagatatatt tgaatataat agggaaggta aacaaagatg tgcttatgaa
    48121 gcattatcaa gaggatatta tgatgctata tttgataatt taatggatgg tgtatgtacg
    48181 ataacatcaa attcagggtg gaaatgggat gatatattaa tagatttagg catgagacta
    48241 tgtgatttag ctcatcaaga ttttgttata aagtgcgaaa aagtagaaga tatatacaga
    48301 gctaaaagtg aaggtaaagt agcattgata ccaacattag aaggtgcagc accaatagaa
    48361 aatgaacttg atagaataga tatactgtat ggatttggta taaggttaat gggtataaca
    48421 tatagcgaat ccaatgcatt aggttcagga ctaaaagaag agaaagatgg aggtcttaca
    48481 aatttcggaa aaaaagctgt tgaaagaatg aataaaattg gaatggcaat agattgctct
    48541 cacgttggag ttcaaactac acttgatgta atagaatata gcaaggaccc aataatatta
    48601 agccatgttg gggcaagaag tttatggaac acaaagagac taactccaga tgaagtatta
    48661 atagcatgtg ctaaaaaagg aggggttata ggtgtagaag cagcacctca tactacaata
    48721 acagagaaga ataaagaaca ttcaatagag tcatttatgg aacattttga gtatattaaa
    48781 aatttagtag gaatagacca tgtagctttt ggaccagata cagtatatgg cgaccatgta
    48841 aaattacact cagtactagc tgctaaattt gatataaaaa aaataacagg aacaaaagaa
    48901 catcccaaag tagaatatgt aaaaggtctt gagaacccaa cagaaacttc aaaaaacatt
    48961 gttagatatt tagtaaagca tggatatagt gatgaggaaa tagagaaggt actaggtgga
    49021 aatatactta gagtactaaa acaggtttgg aaatagatat attagaaata ttaataaaat
    49081 ttgaggattt atagggaggt tttataaatg gattatttaa aattagctaa tcatccactt
    49141 ttgtggatag cgagtacagt agcagtatca atagtagtgg tacaatccct tatatttgct
    49201 ataaaatctt gcaaagttgg taaaacaatg ggaataacag ataaacaaat aaagtcagct
    49261 gttaagagta gtgctatttc agctattggg ccttcaatga ctatatttgc tggaatggta
    49321 tcgcttatag taactatggg tgggcctata gcatggatga gattatcatt tataggttct
    49381 gtaatttttg aatcaatgtc agccggattt ggaacagatg cattaggtat aactttaggt
    49441 tctcctgaaa tgacaaaact tgcatttaca aatgcagttt ggactatgat attaggttct
    49501 ttaggatgga taatattcac attactattt ggacataaac tagataagat aaccaatgtt
    49561 atatctagtg gcaagaaatc atttatacca ataatatctc taggagcaat gttgggttca
    49621 tttgcatatc taaatgctga tagggtgttg cgttttgata atggaacaat tgcatgtata
    49681 agtggaatgg ctataatggt aatattgtgt atgcttgaaa agaagaaaaa tataaaatgg
    49741 ttaagagagt gggggcttac aatatcaatg tttagcggaa tgataatagc ttcagtaata
    49801 taagggggga gttttatgag taaagtaaaa tctatataca atgaagaata tttacctttt
    49861 aagataaggt atggaagact aacactatct ttggggatta tagcagcatt agttcctgga
    49921 ataattttga gctttggatt tggtattatg cctccaatat cagcattatt agcaagtaca
    49981 atggcaattg tcagtatgag tgctccaaat tacataatag aaccagtttc ttattcacca
    50041 atcttaggta tcccaggaac ttatatgagt tttctttctg gtaatatatc taatatgagg
    50101 ctaccatgtt caatagcagc tcaaaaggca gcagaagttg aatcaggtac agaagaaggc
    50161 tcgataatat ctacaatagg aatagctgta tctattttag tgaatataag tatactaact
    50221 ataggggtaa ttttaggagg aagcgtacta tctaaaattc cagctgaagt agtagaaaaa
    50281 ttaaacttaa ttttaccagc tctatttggg tcagtttttg gacaagtatt tttacaagat
    50341 aaaaaattag gcctagtagc aattgtaata tctgtattga ctattatatt atcaaagcaa
    50401 ggtataatac cacagtctct agtagttctt atatgtgtat ttggtactat gttaattgca
    50461 agagctatgt ataaagataa gcttagtgac taattacaat gaaataatag tgaattttca
    50521 aatatgaaat ataataattt gattttcaaa tataaaaatt acattaagat tatttaaaaa
    50581 ttggttttta aggagggaat attttgatat atgatttaat cttaaaaaat ggatttataa
    50641 taggtggtac aggtaatcct ggtttttatg gagatatagc aattaaagac aacttaatag
    50701 caaaaataga ttctaagata aatagcaata caaataaaga gattgattgt tgtggaaaag
    50761 ttataacacc tggatttatt gaccctcatg ttcatgaaga aatagtagca atactagatg
    50821 gtaaatttga aaagtttcta aaacaaggag ttacaacaac tataaatggt aattgtggac
    50881 attctataac accatattct tctgaaaatg tatatgaata tatgtataaa aatggtctat
    50941 tacttgaaga agaaaaaaag tatcttatag ataaaaataa atgttggaat aattttacag
    51001 aatattgtga ccttatatct aaaagtggta tttctgtcaa tatgggattc ttgttggggc
    51061 atgggactat aagatggagt gttatgggag gttctaagga tagacctcct acagaaaagg
    51121 aaaaaaatga aattacagat ataataaatg atggaatgaa aagtggtgct tttggaatat
    51181 ctactggatt ggcatatata ccaagtaagt atgctgatat tgatgaactt gttgatattg
    51241 caaagcagat taaagagcat gatggtatat atacatctca tattagagat tacataggaa
    51301 gatataatgc agtaaaagaa gccatagagg ttgggcaaaa aagtggtgct agggttcaag
    51361 tatctcactt aagtccagtt gaaatagaag catttgatga gatattaaag gctaggtata
    51421 atggtgttga aataatggtt gacacagtac caagaagttc tgggcattgt atgaagaaaa
    51481 aaagagtaat tcaatttatt atggcaatat catctagtct atttgaatta ggtataaatg
    51541 gggtaatgga tgctcttaga aatgaagagg gaagaacact tatattaaaa gaagcattta
    51601 tacttggaga tagggggagt ataatacttc taaacactaa agatattaat atggaaaaga
    51661 aatcaatacg tgaaatagct acacaaaaag gaatagatga agacaagtta ttactcgatt
    51721 tacttttaga tggagacgaa gaacttatct tttgtttagg aggaatgtat agagctgatt
    51781 tcccagataa actacatgat gataaaataa ttgataatcc atttgttatg gttggttcag
    51841 attgtttgtt tagtgtgggt ggggatatgt catggtttga actacaaaga agaggagctt
    51901 ttccaatttt cttcaatatg tacagaaagt ctggtgttag attggaagag attgtaagaa
    51961 gagttacttc attaccagct aggcaattta aaataaaaaa tagaggtatt cttaaagaag
    52021 ggttgatagc tgatatagca gttattgaca tggataacta tagttattct aggtcagaag
    52081 atattgattt ttcaaagcca caattactag ccaatggtgt tgaatatgta attgtaaatg
    52141 gaaaaattgc gttggaaaat ggagagatta ctgagaataa atgtggtgaa gtattaaaaa
    52201 gataaggttt taaaaataat aggatttaga aagtaaataa atatctaagt aagtaaagac
    52261 gaagtttgag atttatttaa ataaaaatca tgcttcgttt ttatttatag tattaatatt
    52321 tattttaata atcagataat atttatactt tatagtgaaa aaattaatat ttttaatcat
    52381 taaattatgt aaagaattgg ataaatagat aactaaatca tttgagaaaa gatttttaga
    52441 aataaaaaat gataactaaa taaccccttt aatatttatc aaatagccag tcataaatat
    52501 taaaaggggt tatttagttt ataaaaatta tttgtaataa agtaggatat attaataaat
    52561 atgatagaat atatattata aattaaattt attaatataa ggggggaact ttgagttctt
    52621 atagatttct tacattataa gaacctatac tttatgcggg agttattaaa agtaacactt
    52681 atagtaatgc ttgttttgat aaatgctttt tttgtagctt gtgaatttgc tatggtaaaa
    52741 cttcgtagtt ctaggattga taccatgata actgaaggta ataataatgc aaaaagatgt
    52801 aaaataataa aagacaactt aaattcctat ctttctgcat gtcaacttgg tataacactt
    52861 tgttcacttg cattaggttg gatgggagaa tctacagtta aagagttaat tttaccaata
    52921 gtaagtgtat ttaatcttag tgaaagtatt atatatacta tatcaatttc catttctttt
    52981 ttaattataa caatgatgga ggttgtaata ggagagttgg ttcctaaagc tttagcactt
    53041 tataatacag aaaaaataat gttgagtaca tcttttttat tagtaggatt ttataagtta
    53101 acatatccaa taatatattt tttcaactta agtactgatt tatttcttaa accatttgga
    53161 tattcacaag ctgatgaggt tgatgaaccc catacaggtg acgaaataag actattagta
    53221 gaagaaagtt ataaaagtgg acttatagat gaatcagagc aaagattagt tgataatatt
    53281 tttgaatttg aagaaaagaa aattagagag ataatggttc ctagaactga tatggtatgt
    53341 atatatgaaa gtgattctga agaaaagata ttagctattt taaaagagga aggtgttaca
    53401 agatatccag tatgcagaaa aaataaagat gatatattag gttttgtaca tataagagat
    53461 ttatacaatc aaaagataaa tgaaaataaa attgaactag aagaaatatt gagagatatt
    53521 atatatatat ctgaaaattt aactatagat aaagctcttg agagaataag aaaggaaaaa
    53581 cttcaacttg ctatagttgt ggatgaatat ggtggtacat ctggtgtggt aacaatagaa
    53641 gatatactag aagagatagt tggagaaatt caagatgaat ttgataaaga agagactcat
    53701 attaagaaaa taggagcagg ttcttactta gttgatggaa ctgaatctat caactatatt
    53761 aataagtatt ttggacttga tatagagcat gatggatttg acagtatagg tggatggata
    53821 tcctatatgc ttggttcaaa tattaaagta aaccaaagtg taacttttga aaattacaat
    53881 tttacaatat tagaattgga taaattgagg gttgtaaaat taatcataaa aagtgtaata
    53941 taattatatc aaaaaatatt ggaggaattg tatgcaaaaa gtagaaggaa ttatttttga
    54001 catggatgga gttttgtttg actcagagag aatttctctt gaattttgga tggagacgtt
    54061 tgaaaagtat ggatatacta tgactaagga aatttataca tcagttatgg gaagaaatcg
    54121 taaaggaata atagaaggtc ttacagatat atacgatagt tctgtaccaa taatagattt
    54181 atatgacgaa aaaactaaaa atatgattga atttatggag aggaagggag ctcctatcaa
    54241 attaggagtc aatgaactaa tctctttttt aaaggaaaat ggatacaaaa tggctgttgc
    54301 aacatcaaca aagagagaaa gagcagtaaa gagattagct aaggcaaatt taaaagatta
    54361 ctttgatgct atagtttgtg gagatgatgt tgtaaactcg aaaccaaacc ctgagatatt
    54421 cctaaaagca gctaaaaaga taaatgttaa tcccaaaaat tgtattgtca tagaggattc
    54481 gcctatggga gttgaagctg catacaatgg tggtataaga tgtataaatg taccagattt
    54541 aaaagagcca gatgagcaaa ttaaatcaca atcacataag atacttgaaa atttactgga
    54601 agttagagaa tacctaaaaa gtttgaactc taaagaatgt cacaatctat aatataaagt
    54661 attaattaaa taaattaaat ataatttctt tgatttagaa taaatccatg aatatgagaa
    54721 aaaataagta taaacagcta ggaggaatat tcatggataa tgtaggttct ctattatatt
    54781 ttttatttaa ttttttcttg tatggtttta taggttggat aattgaaaac ttatatagtt
    54841 attataaaca agggcatttt caagaagatg gatttttaaa tggtccattt aaaccaatgt
    54901 atgcaattgc aatgtcgatt ataatagagg tctcaagatt tattgacccc aataatatat
    54961 ttgcattgct tttattatgt ctagtagtgc cgacagtagt agaatatatt acaggaatac
    55021 ttatgaaagt atattttaat aaggtctatt gggattattc agattataag tacaatagta
    55081 gaggaatagt atgtctaaag ttttctgtat attggactat attgacattt attggagtta
    55141 gatattttca agtgtatata gttgatagtt tatatagtct tataatacct tattggccaa
    55201 ttgttgtaac tatactttta gtaacattgt ttgtggatga aattcttact ataaaatttt
    55261 tgaggggaaa taaagatata gtagaaagat aactttaaaa atataagttg aatttagatt
    55321 gtagttaaaa gaaagctatg ttaaaatggt gaaatcattt aaaattagct ttctttttta
    55381 tttgataaaa ttattttata atatatctat aagttgtaaa gttttttatt aaaattaaaa
    55441 taaagtgtag aaaatgggga gtgatttatg atgggtaaaa taagatttgg tattgttggg
    55501 acaagcaata tagcaaatat atttctaaga gctgcatcta gggttaaaga ctttgaattg
    55561 gttgctgtat attctagaaa tttagaaaaa gctagagaat ttggaactct atatggagca
    55621 agtatttttt ttgatgattt agaacaaatg gctaaatcga aggatataga tgctgtatac
    55681 atagcttctc caaatgcatt acattcaaag caaaccatta cttgtttaaa acacaaaaaa
    55741 catgtgcttt gtgaaaagtc gttagcatct aatttaaaag aagtcaaatc aatgataaaa
    55801 acagccaaag ataataatgt attgcttatg gaagctatga gaattacatg tgttccaaac
    55861 tttaaagcag ttaaagaaaa cttgtataaa atagggaaaa taagaagatt ttttggaagc
    55921 tattgtcagt attcttcaag atatgataaa tataaaaatg gaattataga aaatgccttt
    55981 aaaaaagagt tgtcaaatgg agctttaatg gatataggag tgtattgtat acatcctatg
    56041 gtgaatttat ttggtgctcc aaaaactgta aaggcagttt ctcatatact tcaaactgga
    56101 gtggatggag aaggttcagc tgtatttcaa tatgatgata tggatgcgat aattcagtat
    56161 tctaaagtag ctgattctta tataccatct gaaatacagg gagaagaggg aagtataata
    56221 attgaaaagc ttaatctatt tgaaaaagct attattaaat acagagatgg aagagaagaa
    56281 gatatatcta ttccaaaaga aaaagcagag gaaaagccta gagaaataga aggaatgtat
    56341 tatgaacttg tagagtttat aagtcttata aataacaata aaatagaatc aaatataaat
    56401 tctcatgaaa attcaataat agtaatggaa attatggatg agataagaag acaaagtagt
    56461 attgtttatc cagctgatag tatatagttt atattagaaa atataagaat ttataatata
    56521 tattcttaaa taaatttaat tttaagttaa ggtaaggtgt atacttaacc aagtgttaaa
    56581 atgtcaaatt ataagtatga aaaagtgcta aaaagaaatt tatttttggc gtttttttct
    56641 ttttttttac aattttgtaa cagtatcaaa aaaagttttg acgattttat tacaattttg
    56701 tagttgaata tacatatcaa aactaatatg attaataata acataaattt gaatattttt
    56761 agaggagaga aaatatgaga aaattgatat actttattac accttttata ataggcgtag
    56821 tatttttatt tgggttagac aaatttcttg attctaaaac tgatgaactt ttgagggaga
    56881 aaaatctact tccaattatg gatgatactt taagtgatat aaaagataaa ggggttacag
    56941 caaataatca ttttttaaga gaaaaggata ttatgatttt ggggtcatca gaacttagta
    57001 attcaacaaa acaacatcca aagtactatt ttaatacaaa taggagtaaa aataaggtgt
    57061 ttgcaattgg gagagcctat actcagacat tacaagatgc tgcaatatta ggaagtatga
    57121 atcctaatat tgataataag aaagttgtct tgttaatttc tatgcaatgg tttatggaaa
    57181 aagacggagt cacaagtcac cattatcagt ctagattttc accaatacaa ttttatcgat
    57241 ttttagataa tccaaaaata tctaaacaaa ataagattga atatgcaaaa aaatcaagta
    57301 agttattatg gggaagtgac gagtataaag cagaagcatt atatgctaag ctatatgagc
    57361 ctaagacatt tcctgaaaaa gctgaaaagg tgcttttaga gccttatttt caaggaagaa
    57421 agtattgtat agctcttaaa gaaaagggta ttctttataa acgattaatt aagctagata
    57481 aaaagagagc aacaaaaaga aaaagaccaa taaattggtc atatgagaga aagaaagcca
    57541 ttgaagatgc taaaaaaaga gttggtaaaa atccactaaa tattgataag tactattata
    57601 aagagcattt taaagatggt atagagcaat acaaaggaag agacaaagat gtaaatttat
    57661 taacatctaa ggagtttgaa aattataaac tgatgctaaa tgtatgtact gacttaggta
    57721 ttaagccagt tgttgtatta atcccaagta tggataaatt ctataatttg actggtattt
    57781 ctgaaaaaga aagaaatcag tactacgata aagcacaaaa aatagcagaa agcaaaggct
    57841 ttgaagttct aaaccttaaa gataaagggt cagataagta ttatttaagg gatgtaatgc
    57901 atcttggtac gaaaggatgg gtagatgtct gtgagagatt atttaaaata tttaaagaac
    57961 aataaagatt tgttaactag tatttgttta actatggtta taatattggc gataggagtt
    58021 ctaacattta ctccatttaa agaattgcca tttatttata acggatttta aaggagcatt
    58081 cttatatgaa aattattgaa ggaataaaaa aatattcaaa tacagataga acagcactaa
    58141 tgtgtaatgg agataaactt tcttataaag atttaaatga atattcagat gctatatcag
    58201 tatttctaaa ggatgtatac aaagaagaag atactcctat agtaatttat ggaaataaag
    58261 aaaacatgat aatggcatgt atgataggag ctttaaaatc aggtagagcg tatgtgcctc
    58321 ttgatattag ttttccaatt gatagagttt ttgaagtcac taaagagata aaaccaaagg
    58381 tattatttaa ctttagtgat gaaagaaatt ttggagatat caatgtaatt gatatggata
    58441 aattaaatta tataataaat gaatatcagg gaaaatcatt agataaagaa aactgggtaa
    58501 aagatgatga aaatgcatat atactattta cttcaggaag tacaggaaag ccaaaagggg
    58561 ttcaaataag ttcaaacaat ttagatagct tttcagattg gataagccca tatctaaaca
    58621 tagatggaag tgaaaaagta ataatgaacc aaccagcata ttcttttgac ctttcagtta
    58681 caacaatata ccctggtctt atccatggag ctacattatt ttcaatatca aaagatgtat
    58741 tagcagacta taaagaacta tttagacaat ttagtatctc agatatagct gtatgggtgt
    58801 caactccttc ttttgcagga gtatgtataa ctgaaaaaga gtttaatagt aaaatgcttc
    58861 ctaaccttga gtcaatgata ttcataggag aagcactttc aaaaaatctt actaaagaac
    58921 ttatgagtag atttccaaac acaagaatta tcaatggata tggaccaacc gaggctactg
    58981 ttggtgtaag tgtaaatgat atgactcaaa aggctataga tgatgaaaaa agtcttccag
    59041 ttggataccc tatgtcaaat tgtaaaataa aaatacttga tgaagatgga aatgagctta
    59101 aagaaaatga aaagggtgaa attataataa ttggaccatc agtttctaaa ggttacttca
    59161 ataataaaga aaagactgat gaagtatttt tctatgatga aatagatggt gtaaagtgga
    59221 gagcttataa aactggagat atgggatatc ttttagatgg aaatatatat tattgtggaa
    59281 gaaaagattt tcagattaaa ttaaatggat ttagaattga aatagaagat atagaaaata
    59341 atttgagaaa agtacataat gtaaaaaatg cagtagtttt accagtatat aaggacgaaa
    59401 aaattgctta cttaaaaggt attgttgagt taaatgaaaa gaatgattta agtaatatta
    59461 aaaatgggat gataataaaa aaggaacttg gaaagtatat accttcatat atgattccaa
    59521 gaaatatttc aataatctct gagtttccaa caaatatcaa tggtaaaata gacagaaaga
    59581 aacttatgga ggaaatttaa tgattttttc acaatatgga gattattttt atctttatat
    59641 attattatta acatcaatac cagcagtaat tttaggtcta atgggcaaga atataaagta
    59701 ttatggtatg ttggcaagtt tgtttatgat attcttaata gtaggaattg atgtccaact
    59761 aaagtacttg gtaatattta ttattcttga agtaataata gttaaaggat atgaatatgt
    59821 aagaagaaaa actaaaaata aatacatata ttggggattc ttgtttgcat caatgctccc
    59881 aataataata aataaaatat ctccagttac ttcttttgga ataattggat ttattggaat
    59941 atcatactta aatttcagaa ctatacaaat ggttattgaa atttatgatg gagctataaa
    60001 agaagttaaa atttcaaaga tgctttattt tatgttattt tttccaactt taagttctgg
    60061 acctattgat aggtcaagaa gatttgaaca ggacttggaa aaacaaatct ctagaaaaga
    60121 gtatatagaa gaatacttac tgccaggaat aaaaaatatt gtcatgggag taggttataa
    60181 gtttgttata gcatttttga taaatacata ttgggtatca agaataccta aagatatgag
    60241 ttttataaat attttaagtt atatgtacgc atatagttta tacctgttct ttgattttgc
    60301 aggatatagt ttatttgcta taggtacagg gtacatattt ggaatacaag tacctataaa
    60361 ctttgacaag ccatttatca gcaaagatat gaaagagttc tggacaagat ggcatataag
    60421 tctttcaaga tggtttggag attatatttt ttctagattt gttatgtcat caatgagaaa
    60481 gaaaagattt aagaaaagga ctactgctgc tcatgtggct cagatgataa ccatgataac
    60541 aatgggattt tggcatggtc taacttggta ttatgttgct tatggtgtat accaaggatt
    60601 ggcacttgtg ttaactgata tatatcagcg aaaatctaaa ttttataaaa aacataaaaa
    60661 agataaatgg ttcgagagag tgcagatttt cattacattc catattgtgt gttttggatt
    60721 gctgatattc tcaggttatt tagcttaatt ttaaggagga aaatttatgc aagaaacagt
    60781 tatagaaata tttgaagatg tattagggac tgatgagata agagaagatt tagaccttaa
    60841 tttatttgag acggaacttt tagactcatt agctataatt gaagttttac ttgaaattga
    60901 aaatagatta gggatagagc ttcaaccaac tgatttagag agaaaagata tgtctactgt
    60961 aaataattta gtaaaattct tggagacaag aaaataaatt agtagttaga ctttaaatat
    61021 taatttataa aataaaattt tacaaagtcc atctgatact aatatttgat ggactttttt
    61081 aatgataata caaagtcttt tgaaaataac tttaattaag taaaaaattt aatacataaa
    61141 tatgatttca taaatcttag gtatcattgt aatattatag gagaaaaata tattatattt
    61201 aggaggaaaa tgaatgtctt taaattcgat agatagaaaa aaagaaatac ttaaattact
    61261 agattcaaaa gggaaggtaa acactaaaga attagtaaaa agattagaag tatcatcaga
    61321 aacaataaga agatatttgg aagaattaga aaatgaaaat aaattaaaaa aggtatatgg
    61381 tggtgctata aaaataaatt atggagtgat tgaaccagaa catataaaga gaaacaatac
    61441 taacctagat aaaaagcaaa gtattgctaa atatgcagct aagtttgtaa atgacaatga
    61501 gtcaattatc atagatgaag gtactaccaa tttgcagatt gtagattata taatatctgt
    61561 aaacaattta aaaattatta caaactctta tccagttctg tcaaaattga tttcttacga
    61621 gaatcaaggt ttgtttgatg gagaagttat atttattggt ggaaaagtaa atttaaaaca
    61681 ccaaaggaca gcatgtccaa tatcaataga tgctatgaaa aacttatacg tagataaagc
    61741 ttttatatct agtgaaggta tacttgatag ttttggaatt agtagtatag accaaaataa
    61801 ggcattgttg tcaaaagcat atataaaaaa ttcaaaggaa agttttgtat tatgtgatag
    61861 ttctaaaata ggaattgcta gtatgtataa gatagcagat ttagaggaat tagattttgt
    61921 tatttgtgat gtagaacctc cgaatgaatg gaaggataag ttaaatgaga taaatataac
    61981 atggatagaa gcaaaataaa cccttagttt tatataatac aactatgctc aatacaacta
    62041 aattcataaa atatagtcag ttcatagatt aagattagaa agtaaatttt agattgtaac
    62101 ttaggatttt atgggaatat gatacaaaat aaaaacaact aaatacaact aaaaacagaa
    62161 atttaatata tatttaacct aaatatgatg tataattaac atatgaaagt tatactttaa
    62221 aagtaaaaac aattaaaaac acaaaaattc taaaaagaat ctatggaggc tataaatatg
    62281 aaaaagatat atggagaaaa aataaaagca gtagtattcg attgggctgg aacaacagta
    62341 gattatggat gttttgcacc tcttaatgta tttatagaga tatttaaaag aagaggtata
    62401 gatgtaacaa tggaagaagc aagaaaacct atgggaaaat taaaaataga ccatataaga
    62461 gaaatgtgtg aaatggatag aataaagaat atttggtcag ataagtttgg taaagtgcca
    62521 actgaagatg atgtaaatga actttatgct gaatttgagc caatgttatt tgagacatta
    62581 gaagagtata cgactccaat tcctcatgtt gttgaaacta ttgaaaagtt gagaaaaaat
    62641 ggattaaaaa taggttctac aacgggttat acaagagaga tgatgaacat agttgaacca
    62701 aatgcagcaa agaaaggata ctcacccgat tttcttgtaa caccatcaga agtatctcaa
    62761 ggaagaccat atccttggat gtgctataaa aatgctgaag ctttaggggt gtctcctatg
    62821 agttctatgg taaaagtagg agatacaata agtgatgtaa aagaaggcgt aaatgcagga
    62881 atgtggagtg ttgctgtaat aaaaggttca agtgagttag ggcttacaca agaagaagta
    62941 gagaacatgg ataaggaaga attaaaagct aagatgagta tagtttcaaa gaaatttaaa
    63001 gaggcaggag cacattttgt aatagaaact atggctgagt tagaagatat actaataaaa
    63061 atagagaatg aaactattaa atcagatttt gtaccagaaa atgattacat attacttaca
    63121 ccaggaccac tatctactac taaatcagta agagcatcta tgttaaaaga ttggtgtact
    63181 tgggatgttg aatataataa cctagtacaa gatgttagaa gaagattagt atctctagca
    63241 acccaaaata cagataaata cacaagtgta ttaatgcaag gaagtgggac tttttcagta
    63301 gaagctataa taggaagtac tatttcaaaa gatggtaaac ttcttgtaat tgcaaatgga
    63361 gcatacggaa agagaatgaa agatatatgt aattatctta acatacaatt tgttgactgc
    63421 acttttaaag atatagaagc agtggattta aatgtagtag aaaatttatt aaaagaaaac
    63481 aaggatataa cacatatatc aatggttcac tgtgaaacta ctacaggtag attaaatcct
    63541 atacaagagg tagggaaact tgcaaaagaa tataacaaaa tttatatagt tgatgctatg
    63601 agtagttttg ggggaattga gattgatgtt gaagatttta atatagattt tttagttagt
    63661 agttctaaca aatgtataca aggagtacct ggatttggtt ttataatagc taataaagag
    63721 aaattatcta aatgtaaagg tatagctaaa tcattatctc ttgatgtgta tgcgcaatgg
    63781 gagactatgg agaaaaataa tggtaaatgg agatttacct cacctacaca tgttgtaaga
    63841 gctttttatc aagctttatt agaattggaa gaagaaggtt ctgttgaaaa aagatatgct
    63901 agatataaag aaaatcagtt tacaatagct tcaagattaa aatctttagg atttgatact
    63961 ttggtgaatg ataatgctca atcacctgta ataacaactt tcttatatcc taaaaatgca
    64021 aagtttgaat ttatggaatt ttatacttat ttaaaagata atggatttgt tatctatcca
    64081 ggtaaattga ctgatataga tacatttaga ataggtagca taggtgaagt ttatccaact
    64141 gatatggaga gactagctga tgtaatagaa aaatttatca atagatagaa gaagatagtg
    64201 tcttgtaggt tacagaatag tgtggaaagc ccactccttt aggtgtgtga gatgatagca
    64261 caaacagtgt ataaaaagta ttgacagtag aatttaaaga cttatatttt agaagtttat
    64321 acaatgaata tataaagatt gagtaatagg gatatatttt atttaaacca caatctaaga
    64381 aattagattt atagtttaaa taaagcattt ccctattatt tttatgccta tttatagaaa
    64441 ataaatgata gttgctttat taagtattat tatcatactt gacaacgtaa caatgttttg
    64501 ttatattagg tttaaagata aaatacggta aagaaaggat atcattatga atgaagaatt
    64561 aagttcacta agatttgatg gtgttggaaa atgtaaaggt ggaatttttg ataatgttaa
    64621 tatatcagga acaggcaaaa tagaaggaag tgtaaaatgt agtaaatttg attcttctgg
    64681 ttcagcaaaa gtttttggga caacagaatg taatgaattt tttacatctg gtttaagtaa
    64741 agtagaagga aacatactgg catcaaaagt tgagatatcg ggacttctta gatgtacagg
    64801 aaatattaat tctgttgaaa ttgatactag tggaattatt aatgtagaag gaagtataaa
    64861 atctgatatt attcatggag aaggatattt aaaagcaaat gagaatatag attgtgaaaa
    64921 tatcaattta agtggaatct tggagtgtaa tggatttttg aattgtgaag aagttaatat
    64981 tagtttaaat ggaacttcta attttaatga agttggagca agtagtataa atataaaaaa
    65041 ggggcatgga gattattgca aaaaatttcg tatgctagaa aaaaagcata tcaactttga
    65101 aaaagtgtct tcaaatttga taagtttagg tctattatca attagaaagt atacagaaag
    65161 taaattgttt gcaaatatta tagaagcaga tgaaataagc ttagaaaata gtgaagtcaa
    65221 agttgtaaga ggaaaaaata ttaaaatagg caagggatgt tatgtagaaa gtttggagta
    65281 cagtgaaagt atagagattg atgaagattc aatagttggt gaaataaaga atataagtga
    65341 aaaaataaaa ttaaagaagg ataagtaata agtaggttta aaaataaaat ttaaaatgag
    65401 gtaataatat ggaaaaaggg tctataaaaa tacttggaga aggctttata agtagtggtg
    65461 agtatgaaaa tataaaaatc gtgggaagct ctaaatcaaa aggaaatgtt aaaagtaacg
    65521 aagtaaaagt tcttggagat gcaaaatttg aaggtgacat caatataaaa aattttgttg
    65581 ttaacggaaa aactattata agaggcaatc ttaaagcaga gcgtgtaaga gtgaatggtc
    65641 aacttaatat agagggagat gcagaaatag atgacttagt tataactgct caacagaaag
    65701 tggatggcaa acttaaatgt aataatgtta caataagagg acaattaagt gtaaatgaaa
    65761 atatgtatgc acaagatata aaaatctatg gcgaaatgag aaataaatca aatatagaat
    65821 gtgaagatat aaaggtatat ggagcaataa aatgtgatgg tcttttaaat ggagaaaata
    65881 tatatgttta ttcaggagga ggttcttatt gtaaagagat aggggcaact aatataaaaa
    65941 taggaagaag caaagatgct ttttcattaa ttaaaatcat taatattttt tcaggaaagt
    66001 ttaaatgtaa tttgatagag ggagatacta ttgaattaga agatgcatca ataaaagata
    66061 tacgaggtaa aagcatatct ctagtagata attgtgatgt tggaaatatt gaatacagtg
    66121 ataatttatc agtttcagat aattctactg taaaaaacag tataaaggtg ggctagaaaa
    66181 gttatggaag aattaatatc taagaaagat ttattgagca aaactaatat atcttatggt
    66241 caattatata gatggaaaag aaaaaacata ataccagagg aatggtttat aaaaaaatca
    66301 gcttttacag gtcaagagac tttctttcca agagataaaa tactagaaag aatagagtta
    66361 atattgtcta tgaaagaaga gacttctctt gatgatattg caaatatgtt tatgaaaaag
    66421 gatattaata aagaatttga cattgatttt attctcagta aagaagttat atgtaattat
    66481 accaaagaaa tatttcaaaa tttatataaa aaagagcaaa gcataggtaa aaaagaactg
    66541 cttatattga gcataataga gaagttttta gttaaatcta taataacttt tgaagagtta
    66601 aaattgatag tgaatataat agaagaaaat tttacatcaa tatacaatga aagtggaaag
    66661 atttatttgt ttagaaagtt tggagttcca ttcgtagtag gatgtctgga ttataaaaaa
    66721 gtaaagtttg aaaaagatgt agttaagatt attgagattg acttgacaaa agaaataaat
    66781 gatataagta taaagttatc atagtgtatt atcttatata atgtattata ataatatact
    66841 taaaatacac tttatttaaa tatttagttt aaagataaga ttttatgtga gtatgtaaaa
    66901 gttaaagata gatttaagta ggttataggg attagtaaac aataaaatga accatgatga
    66961 attactataa attgtattta aactacattt tctacttata gtaatatcaa tggttcattt
    67021 tattgttatt aagataatac agtatttata aaaatacttg atataaatat agtaaattgt
    67081 ttaaatagaa ttattgcctt aatttattca aataatgagt ttttaaaatc taagaaatat
    67141 ccttgtggat gaagacatac aggacaagct tttggagctt ctttacctat atgtatatgg
    67201 ccacaatgtg tacatatcca ttgtatatct tcatttcttc tgaataaagt accttcttct
    67261 aaatcagtag catatctacc aaatctatca ccatgaactt tttctatttc agctatattt
    67321 tcaaataact tagctataga ttcaaatcct tcttcacgtg ctgtttttcc aaagttttta
    67381 tatacatcat cccactcttg aagctcatta tgttgtgcag ctttaaggtg ttgtgctgtc
    67441 ttgtcatata aatctacagg gtatgctcct gatatactta tattttcacc agcaaattct
    67501 tttaatttag aaaagaattg ttttgcatgt gatttttctt ggtcagcagt gtaattaaat
    67561 aaagactcta ttatatataa tccttctttt tttgctacag atgcagaaat attgtatcta
    67621 tttctagctt gactctcacc tgcaaaagct cttaataaat tttctttagt tttactatct
    67681 tttaaattca tattctacct ctctatcaca ataaattttt acaatatttg attcttttta
    67741 tttattattc caataggaga tataattatg ctcaatttag tcagcatttt taaaattatc
    67801 attaattttt tttaaaattc taagaaattc ttgtttctca ttttctgtaa tattatgata
    67861 tgccgtctct ttaacttgtg ttgagatgct attaaaagta tcttctataa gcagtgcctt
    67921 ttttgtaagc tttatatacg tgatacgttt gtcatttgta catttttgtc tttctaaata
    67981 tcctaggttt ataagtttat taaccaacac tgtaacagtg gatttatctt ttcctatttt
    68041 agctgcaatt tctttcattg taagtattcc attattttca taaagtgcag ttaaaatatt
    68101 tccatgagta ggtattaact cacctaaacc atttttactg agtttatttt caatgaattt
    68161 aatcatacta gcctttgttt tacttatgaa atgtacaata tatttatctt ccataaatta
    68221 ttctccaatc tttaatctat ttaaattagt ttgacataaa actatttata aactataatt
    68281 agtttaacat aaaactaaat gtattgggag gaaatttatg aataaaaaat ttaaatcact
    68341 atatattaca gaagaagaag gaaattttag aagaaatata gttgaaagag aagtggatac
    68401 attgccagaa ggcgaagttt taataaaagt aaaatattct tctttaaatt acaaggatgc
    68461 actttctgca aatggtaata agggtgttac gagaaagtat cctcatacac caggaattga
    68521 tgcatctggt atagtagaat ctagtagttg tgatgatttt aaaattggag aagaagtttt
    68581 agtaacaggt tatgacttgg gaatgaatac ttctggtggt ttttcagaat acataagagt
    68641 tccttctagt tgggtagtta aacttcctaa aaatctttca ctaaaagaag caatggatta
    68701 tggtacagca gggtttacag cagctttatc tgtgtataaa tttatagatt ctgtagacaa
    68761 gaatatggga gatgtattag tcactggtgg tactggagga gttgctgtaa ttgcaactaa
    68821 aatattgatt aaattaggtt attcagttgt agtttcaaca ggaaaattag aagaacaaaa
    68881 agaagtatta ctaaacttag gtgttaaaga tgttatacat aggtcagaag tggatgataa
    68941 ctcaggaaga cctctgctta gaccaagatg ggctggagta atagatacag taggaggaaa
    69001 tactctagca acagcaataa agacaactaa ttattgtgga gcagtaacaa cttgtggtaa
    69061 tgcaggagga gttgatttta caagttcagt atatccattt atcttaaagg gaattacttt
    69121 atatggtata gattctgtgg attgcccaat gaacttaaga ttaaaaatat gggatttatt
    69181 atcaaatgaa tggaaattag atgatttaga tgatatggta aatgtagtat cattggaaga
    69241 gttaaatgat agtatagatt caataatggc aggaaaacat gttggaagaa cagtagttga
    69301 tttagaaaaa atataggtga ataaatttat aattaggatt ataggtttta agcaaaaatg
    69361 agatacttga aatttactta tgagtatctc atttttttat gtaaaaagat ttatgtagat
    69421 gtttgtgtaa aaagattatt catgaacaat taattcaaat acatctggtc ttgaatagtg
    69481 accttctgaa tcaaaatcta gtctactaag tactattttt tctaggtcta aatcagctat
    69541 tagcatttct tctttattga aaataggacc tgctacatat tttccaaaag ggtcaactat
    69601 acaacttcct cctggacaca taatttctgg ttctgcatct agctccttat agtagttaag
    69661 gtcagttggg tacgtatttt tttcaacata ttgattgcat ccaattacaa aacatcttcc
    69721 ttctaaagca atatgtttca tagttgcttg ccactcttct cttgaatctg cagtaggggc
    69781 tatgtaaagt tttacaccct tagcataaag agctgttcta gctaatggca tataattttc
    69841 ccaacaaatc aacgaaccca tttttccata tggagtatca actactgtaa gagtacttcc
    69901 atctccttct ccccaaatac atctttctgt tcctgtaggt ttaagttttc tgtgtttacc
    69961 aattagctta ccttctggag agaaaaataa gtttgtgcaa taaagggtac aatttatatc
    70021 attaccatct ctttctgtta tacccattga tagatatact cctgcttctt gtgctgcttt
    70081 tcctaataaa tctgttgtag cactaggaac tggtacagaa ttatcatagt atcttttcca
    70141 atcttctcta ccttccattg ttctacttcc aacaacaaat ccaaatgaaa gacctcttgg
    70201 atatgcaggt atgaatgctt cagggaaaac tacgatattt gccccttttc taccagcttc
    70261 tttaattaat cctaatgctt tttcaacagt tttttctaaa tccattatga ctggtgacgc
    70321 ctggacaaca gcaattctta catttttatt ttccttgctc ataaaaaacc tcctaaaaaa
    70381 tatttaaatt ttttgcattg aatagattac atgagatgtt atttgagaac taagatactt
    70441 atattgtgaa taataatgta actgtatatt taaaataata catcatgatt taaaaaatta
    70501 caattgtaca gatataattg agtttagata tttaaattta acaacttata atattttttc
    70561 aattagtata aagcctatta atttgtctta tttacaatga atagtattta cttcttggca
    70621 aacaataatt aaaaataaaa cttttatatg attaaactct aaagaaaaag tttataaaga
    70681 agataatata attaagcaga aaataatgaa aaaaatttat taaagtagac aacgtaagga
    70741 gaattttatg aaagcaaaaa tttattacaa tggaaatatc atcacaatgg aagattcaat
    70801 atgtggagat gctattctta taaaagacaa aataataaaa aagataggaa caaaagaaga
    70861 agtatttgct ttgaaaaata aagatacaga aattatagat ttacaaggta agacattgat
    70921 gccatctttt atagattcac atagtcactt gatagctttt gctactactc taaagctagt
    70981 tcctttagaa gatgcaacca gttttaaaga catagtaaaa aaaatacagg atttcaaaga
    71041 gtcgaataat ataaaaaaag gagactggat aattggattt tcatatgata ataatttttt
    71101 agaagaaaat aagcatccag ataagagtgt actcgatagt gcatcttcag aaaatccaat
    71161 actaatttca catgcttctg gtcatatggg agttgcaaat acattggggt taaaacagct
    71221 tggtgttacc aatgaaacac gtgacccaga aggtggacat ataggtagag tagaaggcag
    71281 tgaagaacca aatggatatt tagaagaaaa tgcatttttt aatgtagcat ctaaaataaa
    71341 acaaccatca tcaaatgaga tttttaattc aattgaaaaa gcacagaaca tatatctaag
    71401 ctatggtatt acaacagctc aagaaggttt aatggaagaa aatcaattta acattttaaa
    71461 agcaatggca aatcaaaata aattaaaaat ggatgttgta ggatatgtaa atttgaaaaa
    71521 aagtaagtct gtagcagata ataataggga gtttataaaa aaatatataa atagatttaa
    71581 aataggaggt tataagattt tcttagatgg ttctccacaa ggtaagacag catggttgag
    71641 tagaccatat gaaaattcag atgatggtta ttgtggatat cctatataca aagatgaaga
    71701 agtagaaaag tttatagata tttcactaaa agaaaagatg caactcttaa ctcattgtaa
    71761 tggagatgca gcagcagacc agttgataga tgcgtttgag aaagttttaa acttaaaaga
    71821 gcaaagtagt gaaaataata taagaccagt tatgatacat gctcaaacag taagagcaga
    71881 ccagattgat gatatgaaag taataaatat gataccttca tattttgtag ctcacacata
    71941 ttattggggt gatattcata tcaaaaacct tggagaagat agagcgttta agattagccc
    72001 acttaaaaca actatagaaa agggattaat ttacactctt catcaggata caccagtaat
    72061 agcacctaat atgctggaaa cagtatggtg tgctgtcaat agaattacaa aaaaaggtat
    72121 acaaatagga gaaaatgaaa agataagccc attagatgct ttaaagggtg ttactataaa
    72181 tgcagcatat caatattttg aagaagataa aaaaggttca attaaagaag ggaaattagc
    72241 taatttgata atattagatg aaaacccact tacaatcgac cctatgaaaa taaaagatat
    72301 taaagtattg cagactataa gagaaggaga agtattgtat tctttgaagt agatgaaagt
    72361 tagatatttt ataatctata aaaaatagtt ttatataata agttaggtag aattaaataa
    72421 gattacagtt aaatcaacaa ttatattttt attaaatttt aattattgta ttgaagattt
    72481 ataagtataa ttttattgat tctacctttt taaataactg tagatttatt aaagttatct
    72541 atgtactata ttaaacaatt aagtagttat taattgcact tattagttta ttaaaaaact
    72601 atgtatatta ctttgcagta agactttgga actaaatcta taatagcaaa tttaaattta
    72661 ttaaatagat taacttataa catttcatat aaaatatatt gtgaatctga gaaaattact
    72721 atttttcttt gagtattttt tgtaagcagt tctaaaagat tcaatttcat acctattact
    72781 tgaatcattc atcaaaataa ttctaattta aaaaataatt ctatccaaat aatagatata
    72841 taggactatg ttataatata aaaaaattta tataaaagtt aataactata caagattgat
    72901 aaagaaaaag tcaaaataga taattgatta gcaaaataga tataattata atgaagttaa
    72961 atctagcaat attctcctaa aattaaattt catttattta attaaatata atttgacaat
    73021 gggcaaaaaa gtgagtaaaa tataaataaa ataaaaataa caggttcgga taaagaaaaa
    73081 ggtttcttaa cctcaagcat aaagtatatt atctaagtta tttgagatta agagataaat
    73141 ccaatcttag gtactgagga ggaaaaaatg cttgatataa aaagaataag agaaaattta
    73201 gattgtataa aaaaagcaat ggaaagaagg ggcgaaaaaa actttaacct tgatgaagta
    73261 gttaagttag atgatgaaag aagaaagact cttcaagaag ttgaagttat gaaaaatgaa
    73321 ttaaatacag catctaaaaa tataccaaat cttataaaag aaggtaaaga tgtagaaaat
    73381 gaaaagatta aattaaaaga gttatctgat aaaattaagg taatagacca aaatcttaaa
    73441 gaagtagaag ataagatgga atacctatta atgagaatac caaatgtacc acatccagaa
    73501 gtaccacaag gtgaaactga tgaagataat gttgaagtaa gaacttgggg aaagactact
    73561 acctttgatt ttgaatctaa ggctcattgg gaaattggaa cagaattagg tatacttgat
    73621 tttgaaacag ctagtaaaat aactggttca agatttactc tttacaaagg attaggtgct
    73681 agattagaga gagcattatt aaatttttac ttagacacga atacaaaagt aaatggatat
    73741 acagaagtta ttccaccatt tatggcaaat agaaatagtt ttttaggtac aggacagtta
    73801 cctaagtttg aagaagatat gtttaaaata gaaggtatgg actattttat gattccaaca
    73861 tcagaagttc ctttaactaa tatacatgct aatgaaatac ttaaatttga acaattaccg
    73921 ataaattata cagcttatac tccatgtttt aggtcagaag ctggttctgc tggaagagat
    73981 acaagaggtt tagtaagaca gcatcagttt aacaaagtag aaatggttaa aatagttgca
    74041 ccagaagaat cttacaatga gttagaaaag cttactaaca atgcggaaac tatgctacaa
    74101 ttattgaatc tgccttatag agtagtaaag atatgtacag gtgatttagg atttacggct
    74161 tcttttaaat atgatgtaga agtttggatg ccaagttaca ataggtatgt tgagatttca
    74221 tcttgttcaa actgcgaaga tttccaagct agaagagcag gaataagatt taaaagagat
    74281 aaagattcta aagctgaata tgtacacaca ttaaatggct ctgggttagc tattggaaga
    74341 agtgttgcag ctatattaga aaattatcaa caagaagatg gttctgtggt tgttcctgaa
    74401 gttttaagac catatatggg agtttctgtt attaaataag agttaaatta tgtattttta
    74461 agtaatacaa taatatagag gtaataaaaa ataattaata taaaagtgat acaataatat
    74521 agaagtaata aaaaaatagt taatataaaa gtgatacaat aatatagaag taataaaaaa
    74581 tagttaatgt aaaagtgata caataatata gaagtaataa aaaaatagtt aatataaaag
    74641 cgatacaata ataatagaag taataaaaaa aaataattaa tataaaaatg tgtacaaact
    74701 aatgaatatt gatatagtaa gctatcatat gaaagagtat gtacacattt tttttactaa
    74761 tttttcacaa tatgaacata aataatttac aggaaaggaa tcttttatga aaattcaaaa
    74821 tactgagtgg ggatatattg aatggaaaca tacttatgat gaaaataatc caaaacaagc
    74881 tatgaatata tacattgcag taactatgcc tggtaagaaa cattttaatc atgttcatta
    74941 tggtcaagag cagatgatat atattttaga gggagagggt ttgtatatta taaatggagt
    75001 ttggaagcca ttttatcaag gtatgatttt ttatatagaa tctggtagca cacatgaaac
    75061 tataaataca ggcgatagag aaataaaaga acttattgtt tcaaataatg tagatgatgt
    75121 aggagagagt gaagttatag atattaatcc taataattat ttaaagaaga ccttgataaa
    75181 ttatagtgaa agtacattaa atttgtatgc agcagtagaa tcaattcgtg gtcaatttat
    75241 agacccgttt aaaattccat taattatata tgatgattca tggaatatag ttttaaaaaa
    75301 tccttatttt ccactttttt gttttgaaaa atgtaatcct atgaaatttc ctcaaaattg
    75361 tgattgtatg aatcaaaaaa gtagcaatca atttgtatgt gaatatggga taactatata
    75421 taatatacca atactgtaca aaagcaatag cataggtgtt ataagaggag ggtatgtact
    75481 attatctgat ttgaatttag atacagagca taataattta tatgatattc cagagggagc
    75541 tgctagaagt ataaaacgcc tcttgaaaca aatatctaaa aatataataa atttttgctc
    75601 ttttaatgat ataagaaagg atttacaaga aaaagagaag actatagcaa gaacatatca
    75661 ttatggagag caacttgaaa tgaatttaaa agtagctcaa gatatggtta ctaatttaag
    75721 aataaatcat cactttttat ttaatacatt aaattcaatg gcaagcatag cactagatga
    75781 tggtagttat gatttgtata gtgcaataat agatttatca agaatgttta gatatacaat
    75841 gaggtctgat ttaagatttg tagaattaga atctgaaata ttatacatta aaaattattt
    75901 gaatttacag aaattacgtt atggagatgc acttaaagta aaatatctta ttccagagaa
    75961 gttatataac ctttctgtgc cttttaactt tattcaacct attgtagaga atgcatttac
    76021 acatggattt agagatattg acacagaaaa gcgaattgaa ataattgcaa gattagattc
    76081 tcagtatgcc attatagaga ttcataataa tggaactatc ttagatggaa ataatataga
    76141 caaaataaag gcaggtattc gtagtaataa tggtcatggt ttgtctttaa tatatacaaa
    76201 attcacatct gcttatggaa ataattttga tatggatata aagtcgagtg ataatgaagg
    76261 aacttacata atgattaaaa ttcctattga aaattataag gagtatgtat agaacttgtg
    76321 aaaaattaat aagttttata aatgttaaga aatatattag atgtttttat gttgttttat
    76381 atatcttact tttttatatt attaagctaa aagggaggta ttctcatgag aagagcacta
    76441 ataatagatg atgaagaagc tgttctaaaa ataataacac attttataga aatgaaagat
    76501 atgccaataa aaattgttgg taaagcaaca tctggtgatg aagcagtaga taaa
//
LOCUS       DAJMZY010000003        74762 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.003, whole genome shotgun sequence.
ACCESSION   DAJMZY010000003 DAJMZY010000000
VERSION     DAJMZY010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 74762)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 74762)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..74762
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.003"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            <1..781
                     /locus_tag="OE968_000167"
     CDS             <1..781
                     /locus_tag="OE968_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HCP7217484.1"
                     /translation="SKIYGIGRDSLMYYEEIGILRPVRDINGYRMYNISDIWKLNLIK
                     EFRSLNFPMKKIKEYLDDRSIESTKNILNEELDLIDKKIAEFISHKENIIKRLSSIES
                     VIQNTKIDEIEVVYIEKRKALELNADIKRDEDFDFLIQKLQKEYEDRFNILGNNNIGS
                     AFSTEAINKGIFNEFKSVFCFLESNEKVYNIVFDEGYYVTLNYTGSNSNNKIYMEKVF
                     KFIEENNYKIIADPIEIYKIDIHETGIVEEFVTEIQVPITK"
     gene            915..1154
                     /locus_tag="OE968_000168"
     CDS             915..1154
                     /locus_tag="OE968_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7217485.1"
                     /translation="MKCSNCGSVNIEKGILTTGGIYAETIGLKYRGDGKLDKVINKTF
                     PVQSTIYSDLCLDCGEIVRTYIKDNTDRNWCKDKK"
     gene            complement(1342..1518)
                     /locus_tag="OE968_000169"
     CDS             complement(1342..1518)
                     /locus_tag="OE968_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7217486.1"
                     /translation="MFRDEMDKCTHMLTAYISSLYDYCDFIDTQLDDFILEYGENVVE
                     SCLHQVMVLVSKYN"
     regulatory      complement(1572..1668)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            complement(2023..2697)
                     /locus_tag="OE968_000170"
     CDS             complement(2023..2697)
                     /locus_tag="OE968_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HCP7217487.1"
                     /translation="MNHHILIQFEYIARIITAGFCGALIGYERKNRLKEAGIRTHFIV
                     ALASALIIIVSKYGFNDIVGTPGIGLDPARVAAQVVSGIGFLGAGLIFIRNQSVSGLT
                     TAAGIWATAGTGLAIGSGLYLVGIVSSIIIVIVQITLHRDRKWMKLPTAEQVSLKISN
                     STDSIEYIEGKFKKSNIEIINMNIKRLDGDWLEVVIYTKLPKGYKKTNLLKLFSDNPL
                     IETLEI"
     gene            complement(2917..3471)
                     /locus_tag="OE968_000171"
     CDS             complement(2917..3471)
                     /locus_tag="OE968_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HCP7217488.1"
                     /translation="MSIALILIDIQNDYFKNGKCELFQSEETAENAKKILLFFRKNNL
                     PVIHIQHISTDKTASFFLPNTHGSEINKIVFPLDNEEIITKHTPDSFFETDLQSILEK
                     KNITNLVICGMMSHMCIDTSVRTAKKLRYDITLISDACTTKNLSWNNIEINANTVHQV
                     FMASLQNSFADVKNTDKFLSNYHK"
     gene            complement(3549..3914)
                     /locus_tag="OE968_000172"
     CDS             complement(3549..3914)
                     /locus_tag="OE968_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCP7217489.1"
                     /translation="MKIRAEYTCLLEIVHDIIKGKWKTILIFELRQSNKTFSELQHNI
                     YGINQKMLIQQLKELRDFGIIDKISSAGYPLHVEYFLTNRGKKMLKAVEIMQEIGIEY
                     MLEHGQQEILDNKGICYNK"
     gene            4379..5164
                     /locus_tag="OE968_000173"
     CDS             4379..5164
                     /locus_tag="OE968_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCP7217490.1"
                     /translation="MIVKIDNTLEKEFWQYVSHEESLNLFIIGYVENYGFSSQYQDIW
                     SQVEDGNITSIILKNKSTLIIYSFKNNFNIGEMKNHIKDLDVESISGKKCVIDRLISK
                     YKDFYEKLDNKFCVLKEIKEIDFSNMKEYKIENAQEKDIDEIGKLLNRSDYKVSKNYI
                     EERKVHLKEGNVRAYFIRNDDTMISTVSTGMETSFLAMVVSVSTDKRYRGKGLASYMV
                     YNLSKELLLEGKVPCLFYNNDVAGKIYHNIGYKEINEWTILFK"
     gene            complement(5261..6085)
                     /gene="pdaA"
                     /locus_tag="OE968_000174"
     CDS             complement(5261..6085)
                     /gene="pdaA"
                     /locus_tag="OE968_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="delta-lactam-biosynthetic de-N-acetylase"
                     /protein_id="HCP7217491.1"
                     /translation="MKKDSLKKYIMIGAFALILFGIASINFKSLDKTKTQISSPTLDT
                     HEYDWYFNPREDGKQPSPIKEADFFKKYGAYYVGNPNEKVIYLSFDAGYESGNTPKLL
                     DTLKKHNAKAQFFVVESYIKSNPELIKRMEKEGHLVCNHSKSHPSMAGITDFEKFKEE
                     ITSVEKAYKDVTGKEMPKYFRPPMGKFSEQSLKYTQDLGYKSIFWSFAYVDWYEKKQP
                     THEFAKNKIYSRTHPGAIVLLHPNSSTNTEILDEVLTHWEKEGYKLKTLDYLNNKK"
     gene            6306..9425
                     /locus_tag="OE968_000175"
     CDS             6306..9425
                     /locus_tag="OE968_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HCP7217492.1"
                     /translation="MDNIISVLNDVVFLDIEVSGLDCLNSEILEVGAVKVKDWKIYTY
                     ESLIKNKFEVPVEVFSVCKNLDKNDLEIANEIELVEDRLVNFVEDSFIICHDLSLKKK
                     FLEYHMPKLKNKFIDLIELAVILEPYHKDYSLEYLKNTLTNCNSKVENRALSDAIDII
                     NIVNCLLVKFNNYEKTTLEPLSFKINSYLKKFNLPTWEWSKFLEEANYDLSNNINIKK
                     EYNIFDSKEEKKKERETLKILNEEEKNYEELLKYKTIWENKEGFTYEYRPGQYELTKT
                     IRELFRNSEDEEKIACIEAPTGIGKSVGYLLPAILEARINKKRLLISTDTKELQIQLI
                     NKDIPNVLDSLGLNGKVSYGYIKGKNNYICIDRLEAYIDDYESQNPTKGEILSLIFLK
                     RLVEGGKYGDIEEINYLVFDNFKEISTHLRNVSCDPNMCRPKKCKKDCLYKNRIEELK
                     EEHITVVNHSLLAKWPYKDEKPLENIIVDEAHNLTEKGYDFFSSIINSKSLRYLLQEI
                     YPYEFIQNSSFIYKKYSRNMRKIKAFDKFYNVLKIGREDKQKIARSINLIIEEIDSIL
                     KFGNCNEYNNVSNYNLRWELNLQIDEIVGKLKKDGIDTEISYRAYSEKIKLSCEKIIK
                     NLVSIIIIIYRNIDDDSIDKEADIYKFGKAKTRDLEDIKIIFEIFLEYDEKDDYARIV
                     EIDKNYNDFEFRVVPLKIADLFEENILSQLEKGIFLSATLSLSESMSYFKNTLGIDRV
                     KNVEKIIEPIFDYKNRVSVVGFSDICEYRNSEFPNEMSKIISNISKITEGHTLALFNS
                     KDRQEKTYEILKKYLHSFNLEIYADKKGIRHLNDLNRKCVVLGSKGCFEGVDIPGDGL
                     VCVTLDKLPNLNPKDPLYFTIMKKYGIDYYTINYPQMTIKVKQAMGRILRSKYDYGCF
                     VIFDVGTNISVLKRLEKDLHDCKISKVNSNEFYTYIRRHLNKYRSLILKSVIFDTIKA
                     LNVDAKMDNNDVDKDIIKKDINENIRQRAVKGEVYHIDIIKKDMKVKYFDRNYLINLD
                     IFMREEDKN"
     gene            9443..10042
                     /locus_tag="OE968_000176"
     CDS             9443..10042
                     /locus_tag="OE968_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease H family protein"
                     /protein_id="HCP7217493.1"
                     /translation="MAKQKFYAVKKGKNIGVYNTWDECKKQVNGFSGAEYKSFSTFQE
                     AKEYIDGSEKLSFQEDKEFIEAYVDGSYEHSVKMYGSGVVILKNNEVIKTYSEKGKEK
                     TLVSMRNVAGEIEASKIAMQYCIDNNVQNLILYFDYEGIEKWCTGVWKTNKEGTIAYK
                     NFYDSIKNKLNVKFTKVKAHSGNKYNEEADKLAKKAIGV"
     gene            complement(10299..12428)
                     /locus_tag="OE968_000177"
     CDS             complement(10299..12428)
                     /locus_tag="OE968_000177"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HCP7217494.1"
                     /translation="MPNLPSLGSKAPDFKANTTNGPIRLSDYKGNWIVLFSHPGDFTP
                     VCTTEFLCFAKYYDEFKKRNTELIGLSVDSNSSHLAWMYNISLLTGVEIPFPIIEDRD
                     MRIAKLYGMISKPMSDTSTVRSVFIIDNNQILRTILYYPLTTGRNIPEILRIVDALQT
                     SDRDNIVTPANWFPGMPVILPYPKNYKELKNRVNSCNKKYSCMDWYLCFVPDNYNDEE
                     VSKKIDNTCSWKKEHTKNIENECNCEHEHHDYLNKALDCKQEHKTDIKDDCNHEKKHT
                     KNTNKVHNSKQDKFKDKSCDEMNFNYDKDESCDKINSSYNKEDSSYEDFYKHNYKNYD
                     YTSEKNTKKIAMKTLKDSKKLVRPQITDPYNPIVENANCPDINPIVAEYVLGNPTNVD
                     AQLLDAVIFAFAEIDQSGNLFIPYPRFLNQLLALKGEKPSLKVIVAIGGWGAEGFSDA
                     ALTPTSRYNFARQVNQMINEYALDGIDIDWEYPGSSASGITSRPQDRENFTLLLTAIR
                     DVIGDDKWLSVAGTGDRGYINSSAEIDKIAPIIDYFNLMSYDFTAGETGPNGRKHQAN
                     LFDSDLSLPGYSVDAMVRNLENAGMPSEKILLGIPFYGRLGATITRTYDELRRDYINK
                     NGYEYRFDNTAQVPYLVKDGDFAMSYDDALSIFLKTQYVLRNCLGGVFSWTSTYDQAN
                     ILARTMSIGINDPEVLKEELEGIYGQF"
     gene            12694..12942
                     /locus_tag="OE968_000178"
     CDS             12694..12942
                     /locus_tag="OE968_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7217495.1"
                     /translation="MMICFAMTFALVLINSVMGVHIGLDYYFLMGSVLTVCLTIGIVL
                     CNARKIFDSKAIHKTRTKTVSNNKKQKSHSRDIKRKIS"
     gene            13108..14499
                     /locus_tag="OE968_000179"
     CDS             13108..14499
                     /locus_tag="OE968_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HCP7217496.1"
                     /translation="MNFRDLFEKAVDFIDEKRKSIVAISLSTLGVIALIIVFFLSSNE
                     FSVGNEANELLKIIEKRQYSIAVDYYTSIEKKFSDSKMERFNKSVSKKINKLLLNSGD
                     KYLDGDISQESFIGLINTVKELNKISIDVDDLLAQADRVREMYKEENTTYDIAINYIS
                     TVSILNGMGSNLDVYKQNIETIKESRDVYDSAVKDQKAYKYYEAIEKYNKVLKEDEKY
                     YSMAQNGKEQCIEEMYDYYISRAEEANTSGDYERALQYIEYLKDDYSDDEKVQSLEKK
                     YKKNLSLYTLTSDDIINVIAKKSGKDKANLSINSLPQMIKNNKYYYAEVYEYDKLINE
                     VLVSAKTKDLYSYKDGKKDYKVDYGDGYFRILEDGSYQFGITKDKAKFVLTNTLDEKE
                     NKYKKIEILDIEKADRYVKSKKSLEELFGKYKNIYYYAVVNKGLFRGKEVYAINIYNE
                     KIYAISENGLNEY"
     gene            14614..16083
                     /locus_tag="OE968_000180"
     CDS             14614..16083
                     /locus_tag="OE968_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanW family protein"
                     /protein_id="HCP7217497.1"
                     /translation="MSNVNKKLVIAIGAVALVVIIFIGIMCMQFKGEKIAKNTYVNGV
                     NIGKLTKSQAKQELAKKYKLENVDFNYNDKSWKVKSKDLNLSTDLDKTVENAYNLNRK
                     SAFFGNLSKTISANFGKKSNLVVAINYDKNKLKAEMEKIAKEIDVDVKDATLDISGEK
                     VKVIPDSDGLKMDISKSMENFDNQTKKGNYKNELVVKATPAKVKKEQLANIDTNLGTY
                     STTFKTSQINRSINIKLATDNISNVLLMPGETFSFNKHTGKRSKENGYKSAPVIMEGE
                     MEEDYGGGVCQVSSTLYNSVLYAGLEIVNVKNHTIPSSYVPKGRDATVADSGIDFLFK
                     NNLKHPVYIKNYVSGNQIVCNIYGSAEDKQNITISTKLDGVSQTTMKRVNDPTMPKGK
                     EKVDKSGRNAYSVSTYRTFNDANGKKIKTEKIANSYYPKKEGIILVGTMEPKPEEKPN
                     TDENKNNQNTNNQNPNNQQKPETPPTDNKPNETQPQPQA"
     gene            16148..16741
                     /locus_tag="OE968_000181"
     CDS             16148..16741
                     /locus_tag="OE968_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fis family transcriptional regulator"
                     /protein_id="HCP7217498.1"
                     /translation="MNLNNITNYVQSICENISNVLDVDVTLVTKDLTRIAGTGIFRGK
                     IGETISEKSVYSLVLKDGKSYVINKEIEENCNKCANRENCKELADICTPVKMGEHILG
                     ILGIAAFNEEQKEKILSKDKELTAFVRSMSDLISFKLDELYKQEVKTIDDLEREAIEN
                     AIKKYGSNTEGMKKVAEALNIGIATLYRKVKKFNIKS"
     gene            16923..18269
                     /locus_tag="OE968_000182"
     CDS             16923..18269
                     /locus_tag="OE968_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HCP7217499.1"
                     /translation="MPRKILDISLIEDNKSDLTFFNIEEEDGDETLKALKQSYVTTNY
                     KEETLLNLQGALNSKSDTTSKELKLESYKRYNNALDLAYKNYITSAINMVNKALEINP
                     KDIDILNLRGLLKLLKCDFAKSFESFYTALCYENNHISRKYVNLISSEDFKTFLGRYN
                     HSIRFINEELNYESIHILENIIEEEPELIEPYVILSLLYDKLGNVKKREGYLDKLKEL
                     DKDNPVFEKNEEEKEDTSKKEEIKKVKRKKSILPYIIVGCVLIGMGIYLIQSKKRIEN
                     LNNQISSKEEKLSETDKKLGETSKKLEKTNKELNEVKNKEPEREITVADEEDLYYQAL
                     NLKKNKEYEKAIDNFKSVVSSGKTKKYISESIYQLAITNKLLGNKDEAIKYYKKYINT
                     YTKNDQYYDDSYYELGMFYYDNGDLKNAQQTFYSLRSEVPDSMYNNSKIKEILSEK"
     gene            18451..18822
                     /locus_tag="OE968_000183"
     CDS             18451..18822
                     /locus_tag="OE968_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HCP7217500.1"
                     /translation="MKVFNQLVIILSIWVIGEYISSFIQGIILIPGSIVGMLLLFLLL
                     QFKVLDLSSIENVSGFFLDNMAIFFIPAGVSLIKSLDLIRENVLVLLLVICLSTLIVM
                     YTTGIIVEKMIKKKEEGQKNV"
     gene            18815..19504
                     /locus_tag="OE968_000184"
     CDS             18815..19504
                     /locus_tag="OE968_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HCP7217501.1"
                     /translation="MYNVLQTPVFGIIVTIVFFNLGRYIQRKTSNPICNPLLIAIVGI
                     ILFLSISKIPYENYKIGADSLNFFLGPVTVVLAVPLYKQFELFKKHMFEIIVGIGCGI
                     VISFVSVLIIGKIANSDVSIINSLIPKSITTPMGISLANSLNGVESITVVAIIFTGIF
                     GGMVASTVFKLGNINHPVAKGIALGTSAHALGTTKAFELGEIEGAMSGVSIGVSGTIT
                     VILIPIIMNFI"
     gene            20024..20890
                     /locus_tag="OE968_000185"
     CDS             20024..20890
                     /locus_tag="OE968_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HCP7217502.1"
                     /translation="MSEVKNTLQKHPVLRYSTMLFGMLMTSIGINGFLRPAHLLSGGA
                     TGIATSINYLTNINVGLLTFLINIPIFILGFIYLEKEFCISSLVNMIVFSLLLGATQE
                     ISNIIPIHDILLQSVYGGILSGLGVGVVFRTRSSQGGTDIIAAILKIKKNIEMKDTAL
                     AINGLIVLTGSFLFGLDLALYTLIGLFLNAYSMSFIKDAMNYQKSVMVMSNEVDLIAE
                     DIMKSLVRGVTFLDAEGAYTHQKKKIIYTIVSSNEIPKIKDIALKYDKKAFISVNDVT
                     EVKGRGFKAKDL"
     gene            21132..21941
                     /locus_tag="OE968_000186"
     CDS             21132..21941
                     /locus_tag="OE968_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7217503.1"
                     /translation="MNLSKEYVNLYDNYLKYINEVNKEIRSIKNMKKRVLKRGDFAPE
                     NEVLELEGKTIRDIDDVDTKKPKNKIYKFSNGDVYVGKFLEGKMEGKGSYTFFVDEGT
                     VMEYIGEFKEDKKNGKGNFIFSNGNEYIGYFEEDMMSGIGNMLYSSKDEYIGTWKNGK
                     KDGKGIYKWSDGCIYAGEFKGGKMEGYGICYNSKGEVLYEGEWKNNLIHGKGTYIWEK
                     GKKYIGEFMHGKKHGQGTFYLNNELVYEGTWKFDKPSIFDRTLDEIFSLRL"
     gene            22085..23149
                     /locus_tag="OE968_000187"
     CDS             22085..23149
                     /locus_tag="OE968_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HCP7217504.1"
                     /translation="MKRLIALVLVVLIVLFYSPELLKEGYDLKEKFFQSEIWNEFLDK
                     ININDNSKKDKKEKSQNLQSNNTEGENLGESDIKNFEKISLGDNLSYVLSSIGKPGRI
                     DISEYGFDWYVYNQYGKEFAMVGLENDEVVALYSNSINSCENQDIKLNQDRQTVRTKI
                     TPLKYKRKGNTRYIINSENQYDIISKEGKYITIFYDIHEENRVCSYLIIDKSTEDEFK
                     NLYPDDSEELKKCFELEVIDLVNSVRNQRGLNSLRYSEQATLSSRKHSEDMRDNNFFD
                     HVNKKNETPFDRMKREGIVYTSAGENIAAGQINAIYAHEAWMNSEGHRKNILGNYNNI
                     GVGVIFGGSYKTYYTQNFYK"
     gene            23177..23896
                     /locus_tag="OE968_000188"
     CDS             23177..23896
                     /locus_tag="OE968_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HCP7217505.1"
                     /translation="MTSWKKKTVYKCLIAVALFCGIVLISNFSKVSALMMDTNGNVLI
                     KHGSREKKLIAITFDDGPHPKETSQVLDVLKKYNVKATFFIAGKHAKWYKEPLVRASK
                     EGHEIGNHTFNHPDISNLSSSQIEEEIVKCEDILKEVTGKKPTLFRPPFGSYREKDLI
                     EIAKKHDYKVVLWTGVDVKDWKNPGANSIADKIINKVQNGDIILLHDYATNDTVEALD
                     MFIPKMIEKGFKFVTVSELIK"
     gene            23920..24504
                     /locus_tag="OE968_000189"
     CDS             23920..24504
                     /locus_tag="OE968_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HCP7217506.1"
                     /translation="MILMIDNYDSFVYNLVQYIEELGEAVVVKRNNEIKISDIEELNP
                     EVIVLSPGPCSPKEAGICIDIVEHFKGKKPILGICLGHQTIGHVFGGDIIKAQQPVHG
                     KVYSINHTNKGVFRGLKNPLNVTRYHSLIVDSNTVPKELEITAITDKGEIMGIRHKKY
                     LIEGVQFHPEAILSEYGHEMLKNFITEARERVHM"
     gene            24506..25855
                     /gene="pabB"
                     /locus_tag="OE968_000190"
     CDS             24506..25855
                     /gene="pabB"
                     /locus_tag="OE968_000190"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HCP7217507.1"
                     /translation="MIREINTKLNSFEIFTIFRNEHDSFILDSAMDKEKLGRYSFISS
                     QPFKVLKYKDTDENPLEVLKEELHKYRVVNDTNLPFVGGAVGYLSYDLGNYIENLPRT
                     AVDDIEMPDMYFGFYNHVIVIDHLVQKTYIATPNIDIELEEKIIDDIEQRILKEEKKG
                     IDSICYEEKEVTPIRLKSNFTKEEFKNAVQSVREYIRQGDIYQANLTQRFSGETELTS
                     FELYRDLRRFSPAPFGAFLNFEDAHILSNSPERFIRCVNKRIETRPIKGTRPRGKDKE
                     EDLRLQQELRNSEKDRAELLMIVDLERNDIGRISKTGSVKVPELFVIEPYANVNHLVS
                     TVVGELKDDKDATDVIKATFPGGSITGAPKIRAMEIIDELEPTQRNVYTGSIGYIGFN
                     GDMDFNIAIRTIIKNDKKVYFQVGGGMTWDSDPDEEYQETLDKAKSIMKALRGYYEE"
     gene            25845..26588
                     /locus_tag="OE968_000191"
     CDS             25845..26588
                     /locus_tag="OE968_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class IV"
                     /protein_id="HCP7217508.1"
                     /translation="MKNNVGFDSSLSKFGIGLFETIRVKNGIAVDLDIHIERMLSSIN
                     CLDLDINYKKDFLINEIVTYIKKENVINKALRITVFDEGYNISIRDIPYNQETYEKGF
                     KLAISPIVRGNSLIHRHKTTNYFENIYTKNIANKTGYNDGIFLNSEGVILECSMSNIF
                     FIKGERVYTPSDRLPILNGIIKKRIIEICDELHIELIENEINISEISSFDFVFVTNSL
                     MGAIKVTEIDKIKFNKENVVFDKIVKLLE"
     gene            26622..27323
                     /locus_tag="OE968_000192"
     CDS             26622..27323
                     /locus_tag="OE968_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7217509.1"
                     /translation="MIGCIYEVYNEEMTKIIENQNTLAVYLVGSSKDVDFTLYDVVIN
                     DIDVFVFVKEGEKQERILFKKKGIEFDVNYFSKDGVKKLLSNREYFFVKEMKDAKVLF
                     DRENISHIIKDISRDIYLEGPSKMSLEEKSFIKQDIGAKILNLKNKEKFDVFEYHFLT
                     NLYLKDIIIGYFNINDKWVPKDKKLLKVLKKENNELFELVSKVSENYDYQRLLDVYNY
                     IFKEIETKEVIKLIF"
     gene            27349..27921
                     /gene="folE"
                     /locus_tag="OE968_000193"
     CDS             27349..27921
                     /gene="folE"
                     /locus_tag="OE968_000193"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HCP7217510.1"
                     /translation="MNKVDKEKIQHAVREILEAIGEDPDREGLIETPNRVARMYEEIF
                     SGLSEEPRDHLKVLFADEKHEELVLVKDIPFYSCCEHHLVPFFGKAHIAYLPKGGRLT
                     GLSKLARVIDTLAKRPQLQERITKNAADIIMEELQPYGVLVVVEAEHMCMTMRGVKKP
                     GSKTVTSAVRGIFEKDIASRAEAMSLITMK"
     gene            27985..28776
                     /gene="folP"
                     /locus_tag="OE968_000194"
     CDS             27985..28776
                     /gene="folP"
                     /locus_tag="OE968_000194"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HCP7217511.1"
                     /translation="MFDYGKRTYIMGILNVTPDSFSDGGDFNNLDIAIQHAKDMVDQG
                     ADIIDLGGESTRPGHSYVDSDEELRRVIPVIKKLKQELDIPISIDTYKADVAEEALKL
                     GVTMVNDVWGLRKDKNMASVIGKYDAEVCIMHNQDGTNYDKDIMESIKDFFKVSIEMA
                     MSCGVKKEKIVLDPGVGFGKDFEQNIEVLRRLNELKDLGYPILLGTSRKSVIGKVLPV
                     EPKKRLEGTIATTVLGIRDGVDIVRVHDVYENLMAARMTDAIYRK"
     gene            28787..29152
                     /gene="folB"
                     /locus_tag="OE968_000195"
     CDS             28787..29152
                     /gene="folB"
                     /locus_tag="OE968_000195"
                     /EC_number="4.1.2.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroneopterin aldolase"
                     /protein_id="HCP7217512.1"
                     /translation="MDKILLSNLGFYGYHGVLKEENFLGQKFFVDMELYIDSREAGLS
                     DDINKSVSYAEVYNVVKDITENKQFNLLEALAENIAEEVLNKFILINGVMVRVRKPEA
                     PVNGIYDYFGVEIRRTRDE"
     gene            29145..29651
                     /gene="folK"
                     /locus_tag="OE968_000196"
     CDS             29145..29651
                     /gene="folK"
                     /locus_tag="OE968_000196"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HCP7217513.1"
                     /translation="MNKAYLGIGTNMGDRFDNLSRACELLKNSDSIYKVKESSLYETK
                     PWGYTEQADFLNMCVEIETEFEPYELLEYCQEIERELHRERIVHWGPRTIDVDVLFFN
                     DVVSTDERLTIPHPRIQDRAFVLIPLMDLNEELIINEKTIKEHLNLLSAEEREEVKEL
                     VGYERKPI"
     gene            29632..30417
                     /gene="aroF"
                     /locus_tag="OE968_000197"
     CDS             29632..30417
                     /gene="aroF"
                     /locus_tag="OE968_000197"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HCP7217514.1"
                     /translation="MKENLFNNNSKIEINTNNKKITVKKDKLIIAGPCAIESYEQLLE
                     TAKFVKSQGANILRGGAYKPRTSPNSFQGLKKEGLEILKAVKDEVGMAVITELMDVRD
                     MDELYSISDIIQIGSRNMQNFTLLSEVGKQNKPVMLKRGIASTITEWIGASEYIAIEG
                     NSNIIMCERGIRTYNDYTRNTLDLAAVPIIQKETGLPVVVDPSHATGVRYLVKPMSLA
                     SFACGADGIMVEVHPDPENALSDGAQSLCFNEFEDLMKSINNY"
     gene            30672..32462
                     /locus_tag="OE968_000198"
     CDS             30672..32462
                     /locus_tag="OE968_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HCP7217515.1"
                     /translation="MNDIKDIIEEIKARCDIASIISEYMNIKQSGANYKGLCPFHGEK
                     TPSFYINTSKQIYKCFGCGEGGDVINFVMKMENLDFMDAVKILANKCGIEINTNMNEE
                     TRIKIEKSKKFQDIHTEAARFYLSNLLGSKNLGYEYLRIRGLDDKIIKKFGLGFSLDS
                     WNSLMNTLISKGYKKQDLLECGLIAKNRDGTNCYDKFRNRVMFPIFDYRGNIIGFGGR
                     VLDDSLPKYLNSPDTLIFNKKQNLYGLNFARKNLESKTIVLVEGYMDLISLYQYGIKN
                     VVATLGTALTEQQGILIKRYADTAIISYDSDEAGIKATLRAIDILTKLGINVKVLDLK
                     DAKDPDEFVRKYGLSDYKKAMDVSTHYIKYKIDHLKKEFNIQKDEERVKFAKEASKII
                     KQLTSPVEIDFYTKYLSNQIDINVESIKREVYGKNYNKPYNNKNQKKIEEKVIEKVEV
                     RQDGKQLVEETLIKIMLEDKKIREIALLKVEESDFLLKESKEILNYMIKNQELDKITI
                     DKLKSLNISEEYLKELNSISLNSINLENTKEIEGIITNIRKNSLEEQINSLLREQQEL
                     ENNNDMKEVDGRVMEIALKIVEINKILKSL"
     gene            32480..33646
                     /gene="rpoD"
                     /locus_tag="OE968_000199"
     CDS             32480..33646
                     /gene="rpoD"
                     /locus_tag="OE968_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HCP7217516.1"
                     /translation="MENKSNKKELKKVTAKTLIEKGKKQGSLTLAEIMEAFSETELDK
                     DQVENLYETLGNLGIEITETKNYKADIDFSVADDDLSIGHLDEDAEAISHDDSSAIEI
                     ETVDLSLPKGISIDDPVRMYLKEIGKIPLLKPHEEVEFARRMHEGDEIAKQRLVEANL
                     RLVVSIAKRYVGRGMLFLDLIQEGNLGLIKAVEKFDYTKGYKFSTYATWWIRQAITRA
                     IADQARTIRIPVHMVETINKLIRVSRQLLQELGRDPKPEEIAKEMEMTEDKVREIMKI
                     AQDPVSLETPIGEEEDSHLGDFIPDDDAPAPAEAAAYSLLKEQIEDVLGSLNDREQKV
                     LKLRFGLEDGRARTLEEVGKEFDVTRERIRQIEAKALRKLRHPSRSKKLRDYLD"
     gene            33811..34500
                     /locus_tag="OE968_000200"
     CDS             33811..34500
                     /locus_tag="OE968_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase"
                     /protein_id="HCP7217517.1"
                     /translation="MKLTDRLLKIASLVSDGKKIADIGTDHGYIPVYLLKEGKVPFAV
                     LADVNKGPLDNAHKEVIQNNLLDKVDLRLGSGIEILEIGEVEEVIIAGMGGILISELL
                     EAKKEVAHNVEKLILQPMQAQEELRYYLLNNGYEILEEVLVREDFRIYEIIVAKYTGK
                     NTIIEDEIYYEVGIKLLENKDSLFNDFIEKKIKTYSSIVNKLEGKNGEAIDKKRKESE
                     VAIKKLENLIK"
     gene            34514..35611
                     /locus_tag="OE968_000201"
     CDS             34514..35611
                     /locus_tag="OE968_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HCP7217518.1"
                     /translation="MLLKSLTRKIEKKYPLNLAEDWDNVGLIVGDFDMDVKKVLVSLE
                     ANEDVIDEAISKNIDLIVTHHPFIFGKINKINSGDLKGRLIQKLIKNDISLYSMHTNF
                     DIAFDGLNDYFMEIMEFGNSKVLDITKSENLYKLAVYVPHNYSDELRKVLSNSGAGHI
                     GNYSDCTFSIEGEGQFKPLEGSNPFLGSVNDIETVNEVKIETVVPQKLLGGVISSMLD
                     AHPYEEVAYDLYKLENKGEIFGLGRISKLDKSMTLESLSRKIKEKLNMKHIRVVGNLS
                     TDITKVAVVTGAGSEFVKKAKRQGAEVLITGDVKYHEAQDALDIGMCIVDCGHFDTED
                     IFKNVMKRFLDEFSEIEVIKSNVYLNPFSTI"
     gene            35674..36246
                     /locus_tag="OE968_000202"
     CDS             35674..36246
                     /locus_tag="OE968_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HCP7217519.1"
                     /translation="MKVAVIFHSVCGSTYLLAREYKEALEEMNIEVDIFRVSDEVAKT
                     LPQYYLINSKEYKDEFESINVIKSGKEILDYDAIFMGSPTYYGNVSGPMKMFMDSFSD
                     IWVGTPLSGKIFGCFATAGSQHGGGELALQAMNIFAQHMGMTLLSVPCSVRGGYPAYG
                     ILHIAGDNSDIRPNDDAKIGIRDYLKRLNI"
     gene            complement(36306..36773)
                     /locus_tag="OE968_000203"
     CDS             complement(36306..36773)
                     /locus_tag="OE968_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HCP7217520.1"
                     /translation="MFKEMRLKKREMTKEDTVEVLKNGEFGTFSTISENGYPYGVAVN
                     YVYFNDSIYFHCARNGHKLDNISKNNKVSFLVVANESVIPDKFSTTYSSAIVFGKACT
                     VENEEKKNALVEIIKKYSKGFFEEGMKYIEKDMNLTTVVKIEIDHISGKASRL"
     gene            complement(37159..37635)
                     /locus_tag="OE968_000204"
     CDS             complement(37159..37635)
                     /locus_tag="OE968_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HCP7217521.1"
                     /translation="MLSKAEIKYFNECASEILSSEKVQLMRTFPHHGNVSCLEHSLSV
                     AYYSYLLCKKLHLSVDIQSVIRGALLHDFFLYDWHYKGDRKGLHGFTHPREALKNATL
                     FFQINEKETDIILKHMWPLTVKPPRYKEAFIVCLLDKFCCLVETLKIHSLLSPYHV"
     gene            complement(37755..38846)
                     /locus_tag="OE968_000205"
     CDS             complement(37755..38846)
                     /locus_tag="OE968_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1648 domain-containing protein"
                     /protein_id="HCP7217522.1"
                     /translation="MSKIECLFTIFPVLILMYATFYFMPYFVGKKHIYGVSIDQEHKN
                     YNYFIKLDKEFKKLLSLGFIIDFILVFILVFTFNKLELSYFIGIIGFLLYESILYIHT
                     HKKAKKLKSEIYSKLGHIDIDSKLIVDMDFINKKNKIIKKFKIIYLIPILFTLGMSIF
                     IAFNYNQLPDSIATHWNINGSPDVFIDKSFLNVFKLIGTDFCLMVLLYITSIGSIKSR
                     IKIDTNRIEESRVENIKYLNKIGYLFLILMIIMTTQFFTTLLSIKTKLSTAMNITTLL
                     VIIYLIATYINSPNLKFNSSYSPEEDEKYWIAGIMYNNPNDPSLMVNKRFGIGWTINF
                     GNPLGKILYIAIALLLIFSLFSLIKSLLL"
     gene            complement(38839..39228)
                     /locus_tag="OE968_000206"
     CDS             complement(38839..39228)
                     /locus_tag="OE968_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCP7217523.1"
                     /translation="MVLNLDFNSDKSIYVQIKEEITKAIASGELKINESLPSVRSMAE
                     NIGVNLHTVNKSYNELKEEGFLNIDRRKGAIVAQLPMKIDNTTRQKNKLDLELLVAKS
                     YLSGISKEEFLSLSSSLFDKYEVKYYE"
     gene            39420..39866
                     /locus_tag="OE968_000207"
     CDS             39420..39866
                     /locus_tag="OE968_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7217524.1"
                     /translation="MLTYLMKRQMHKKDDGMSKPMMITGAVITGVGAYAVYKMVKSHK
                     SNSQMVNTNYYGNSDYDDYKYDEFDYDCDCRDTKQDYEYEELKKKVKEFNSRRINCEN
                     CPHVSQEEMMQYVNSVKDVKEEIDLHEDAKKDNIYKEDEYKKYEEE"
     gene            40130..40855
                     /locus_tag="OE968_000208"
     CDS             40130..40855
                     /locus_tag="OE968_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCP7217525.1"
                     /translation="MKRKEIVMLKLLIVEDDSTISFGIKYALEQEGFSIDISKDLSSG
                     KEMISSNEYSMILLDVTLPDGTGYELCQYIRGFSQVPIIFLTACDEEVNIVMGLDIGG
                     DDYITKPFRIRELISRIKAVLRRKGNTSEENKKILKFGDLSIYTLEARVYKNDKEIFL
                     TSVEYKLLLILIQNKNTVLSRTQILEKLWDVTYDFVNDNTLTVYIKRLREKIGDDLCE
                     PIYIETVRGIGYKWIGSENSVSI"
     gene            40842..42086
                     /locus_tag="OE968_000209"
     CDS             40842..42086
                     /locus_tag="OE968_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HCP7217526.1"
                     /translation="MFLYNPEVKKFLSKYVTLMFIVIIISIGFSIINVSLTKEMVVRN
                     NQAIIGTLSSKYPNLESQIVDIITQGKSMENIDYGQKILIKYNYDKSIRINSEPIISK
                     LVLETIKINIILVCIIFILIFVLVVRYFKSIYNDLSDMTKYVYYSSEGKPFDMKNKNQ
                     EGQIGLLKTELLKMTTILNEKVELLKREKIFLNNTISDISHQLKTPMTSLIMLNDLLY
                     NDVPYEVKIDFLNKIKNQLNRMDWLIKSMLKLSKVEAKVINFKKDKVKFSELIHRAML
                     SMKIPMEIKNQKLTIEGNDNVSYIGDIDWSVEALVNIIKNCVEHTPEFGNIIITYKEN
                     PLFSELIIKDEGEGIDKKDIPHVFKRFYRGRSSSKEDSVGIGLAMSKSIIESQNGDIY
                     VNSEKGQGTEFHIIFHKMYDSD"
     gene            42166..42843
                     /locus_tag="OE968_000210"
     CDS             42166..42843
                     /locus_tag="OE968_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003517588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCP7217527.1"
                     /translation="MEILRVENLTKSYGKNETKVDAIKNVSLSVEKGTFIAITGPSGS
                     GKSTLLHLLGGVDRPTSGKVYINDVDIYNLKTKDLAIFRRRNIGLIYQFYNLIPVLNV
                     KENILLPAELDNRDIDREYFDDLMKTLGLIDREKHLPNQLSGGQQQRTSIGRALINRP
                     SIILADEPTGNLDSKNSKEILELLKLSVKKYNQTLIMITHDKNMALQADRIISIEDGI
                     IKSDEVM"
     gene            42844..45405
                     /locus_tag="OE968_000211"
     CDS             42844..45405
                     /locus_tag="OE968_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCP7217528.1"
                     /translation="MNLYTLLTIRYLKQNKRRTIVTIIGIILSTALICGIGNIFESFM
                     DYQMRETIKNDGSFHVTFYDVNRKNVEYVTKSAEIEKHAFTKQLGYSKLENSENAILS
                     IKQYDKNAINGYKVSIKEGRFPAKEGEIVLSESIINLIDDKLKIGDKITLKVGDMFDS
                     SKKKIDSMTFHEGDYIANEKDRTFKVVGIIEKPGFERYNGIATAIAYFNPMNNYNDTI
                     NVSVAVRNPKDVYKISNKISKNIYSNKDKEAVSDMIKYNEHLLRLQGASKYSNINNSI
                     KSIIIAVTILVIICTIATVYNSFSISINERKKQFGILNSIGATSSQIKRLVFIEGIII
                     SLIGIPIGLISGTVAIDLLFKIINKYFTESVVTKMSLQIVYNPIITIVSIIIVLLTIF
                     ISILLPAISASNISHLNVIKNTGEYKVGKIKSSRLIKMIFKTEGVLAYKNIRRNRKKF
                     IITLFSLMVSIIIFISFSGFTLLLLRGEEIRNSQRKYDLYLTAKNTARSVEDTISELE
                     DIDGIKNFELATGQYVSIRVSENKINKSKEDLIRKYYQKYKIGDSYEYDFSNNELIFP
                     GDFAVKNKINNLVQGSFNKERAIEENGVILVRKSAFEENGKKGVVELTNYKVGDTVNC
                     EYLDENALSKKVKVKILAITDEERLGLGYQNMGLQFITYDEVAKNLNLKLSKSLIFID
                     SGGSIKTKKEIEALANKNNFNFYDESASNESEKQDLKVIKIFVYGFIVVISLVSVTNI
                     LNTVSTSINLRKRELAVIQSIGVTPKGFRKMIYLESFIYGILSLLFGIPISIGIILIM
                     NKLISGVIEFSPIIPWTAIVICIVSVFIITFIAGYIPMSKLNKENIIDNIRRESI"
     gene            45596..46870
                     /locus_tag="OE968_000212"
     CDS             45596..46870
                     /locus_tag="OE968_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HCP7217529.1"
                     /translation="MITISHITAKNMYKSLEERINKFPQGAPPSDTLYKILNVLYTEQ
                     EAKLVAQLPIKPFRVKTAAKIWSVSESEAYRVLDKLASKALILDIEDNKGKKYIMPPP
                     MAGFFEFAMMRTRHDIDQKLLAELYYQYMNVEEDFIKDLFYSTETKLGRVYVQEEVLT
                     NDNEVSILDYERATHIIDESTHIGISMCYCRHRMQHVGKACDAPMDICMTFDNVANSL
                     INNKFARRVDKIECKELLHQAYEHNLVQCGENVRKGVTFICNCCGCCCEAMVAAKRFG
                     NLHPVQTTSFIPNINHENCVKCGKCITACPIDAISKVKEDGKEYIKIDEDRCLGCGVC
                     VRNCHKNSIMLLKRDEKIITPANSVHRAVLMAIEKGQLQNLIFDNNALASHRAMGAIL
                     SAILKLEPAKKILASKQLKSVYLDKLLSMNDK"
     gene            complement(47031..50072)
                     /locus_tag="OE968_000213"
     CDS             complement(47031..50072)
                     /locus_tag="OE968_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp20"
                     /protein_id="HCP7217530.1"
                     /translation="MFKQRLSKLLSSTLVLSMLFTAAPNITFADNTKDNSEKYQSSDI
                     ELHDYSKNAESYTKTKALAKEKIQTLLSKYGAVSAQYALIDNGKIEISGNGGVYSKQD
                     NKNLNKDNMYSIASISKMFTTTAVMKLVDDGKLNLDTPVVKYIPEFKMADDRYKEITP
                     RMLLNHSSGLMGSSFKNTILLADNDSYGHDNFLKELQKQRLKAKPGAFSVYCNDGFTL
                     AEILVERVSGMSFTNFLDKYINNPLNLQNTKTPENSFDSSKLAKAYVPYWEDAVPQDN
                     LNAIGAGGLYSSAENLCTFAQTFMKNSNGILSPASVKAMENKEYLNGLWPEGEDSILG
                     YGLGWDCVNTYPFNQYNLKALTKGGDSLLFHSNLIVLPDENMAVAVLSSGGSSQLNEI
                     IGQEILLSALKEKGKIKEIKPDKTFSKPQQVKMPSSLKENSGLYASSNMIKVDVNDNG
                     TLTVSSPYIENGPEDKYVYIGQDRFVSEKGNSCLKFVKEKNNITYLNMSSYDDVPGLG
                     QTASLYYVAQKVDDNNISNSVKEVWKKRSGKGYYLVDEKYTSQSYMFGSVKASFSLSD
                     ETPGYIVNTKIMDENNSNAFIEIPGVIGRDLSDIKLHKENGTEYLSFGTLTYVSEDSI
                     TNLPAEKSFTCELESNGYAKWYKIGDDIANKKIEVNLPQNSAFAVYDDKGVPVNYSLV
                     TKNNRVRLPKGGVIVFLGSPNARFEVTYQDEVNASALTGTDRYETSIKISQAGWENAE
                     NAVLINDSAIADALAATPFAYKKNAPILLTGSSQINEKTLAELKRLKVKNVYVVGGEA
                     SINEKSLDTIKSNNISVSRISGSDRYQTSMNIAKELNNISNISKISVVNGEKGLADAV
                     SIGAVSAQNDMPIILTNENSNITEINNLFKNKKIDKSYVIGGEYTVSKNIESKLQNPQ
                     RISGSTRNETNAKVIKEFYKDSKIDNLYVAKNGMNKQDDLIDGLSVGVLAGKTKSPVM
                     LVGNSLDYNQKELFKTMRFKSVTQIGGNGNENSFKQIKEIA"
     gene            50279..50578
                     /locus_tag="OE968_000214"
     CDS             50279..50578
                     /locus_tag="OE968_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HCP7217531.1"
                     /translation="MYKNINKKQLKEMMKNEKDVLLLDVRTKDEFKEYKIENAINISL
                     QELINNIDEIYDYKDKKVVVYCRSGHRSVTACNLLAEEGFEHLYNLNSGIIDYMS"
     gene            complement(50816..53044)
                     /locus_tag="OE968_000215"
     CDS             complement(50816..53044)
                     /locus_tag="OE968_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HCP7217532.1"
                     /translation="MRHLKKTNSLKEILNWNNIKNLRPSKGLKNILEIFKSDLKDIRG
                     NYAVLVIVLGLAFLPSLYAWFNIKASWDPYGSTANMLVAVTNEDKGNEIAGQKINVGD
                     QLIEQLKDNKSLGWQFVDEKTALEGVKKGTYYASLKIPKNFTKDLTSLITDDVKKGEI
                     IYTVNEKINAVAPKITDKGASTIQLQVNQTIVKTVSEIVLGISNGVGAGIEHSLPKLT
                     KVENSLIDLQKRFDHINKTVDLASDATSKLSDTVKDIKSDLPTIKKTLNDTKLLSSDL
                     KKFLEDTNDNLDELSPLIKSDLNLMVDLSSSASSLTLNLIDAVNSGSEDVPKLIDNLS
                     EKLSNLQSLNDTLVDFLTKLNQLTSNNRLDDVIDNLEDSSNKIDSSISTLNDIKNKVI
                     SGQQPSISALNNVLSLSNGIGRINLNILNNFDSKISKPINSIFANSIKVANDIITVLD
                     KAEAKLPKVEEILTTSLKLSGNAQESISLIRERLPLAKGMLDDLIDTLSKISNGEDMK
                     KLVSLLESDILTKSNFLKEPVEVKTEKLYPIENYGSAMTPFYSVLSTWVGILLISALL
                     STSVHGNYKPYEIYFGRGLTFLSIALVQGFIIGTGDILLLGVTAKHPILLIVLLMFTS
                     MVFNFIVYSLVSVFGNVGKAIAIVLLVVQIGSSGGTFPIQVTPTFFQRINPIMPFTYA
                     IGATREAVGGIYAPNLTKDILVLLLFMILSICLNVLLKGPINRVIKPFNDKFGDSNLT
                     GH"
     gene            53337..55112
                     /locus_tag="OE968_000216"
     CDS             53337..55112
                     /locus_tag="OE968_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCP7217533.1"
                     /translation="MRYFKKYIKKYIVLFLTAVFFLTLEAFCDLAQPTIMAKIIDIGV
                     SNKNLDYILSTGAIMIGITFLGAIFAIIRSVISARVSQHFSYDLRQDVFEKINTYSLK
                     QIDKFGRASLITRITNDINQMQQFVNGMMRVFIKSPIMCIGSLIIAIKLNLKMSIIIL
                     IAVLIIFIIILLNMKIGYRLFKNVQESTDKVNSKLRQFLSGIKVVKLFCRYDYENQSF
                     EELNDELFKNSRKATTMMSFFRPTITIIINVSIIIILLIGRHLIYSGEIKIGIIVAYV
                     NYMTRILTSLIMISHVFNVFVRAKASYERISEVLVDENEEVIEREESLDVGEKDLKFV
                     NCDIIFENVDFSYNKNTDEKILKNVSFKIEEGQNIGVIGQTGSGKTSLVNLIQKLYII
                     DKGDIKIGGRSIYSISEESLRARIGVVFQNSSVFGKSILENVVMGNRDICKEDVVKSC
                     EIANANQFITKLENTYDEVLFQRGKNLSGGQRQRITIARAIAKKPQILILDDCFSAMD
                     INTETIIRKNIKEYISNLREKESKKCTVITISQKISSIIDCDKILVLDEGEVVGFATH
                     EDLLVSSPIYKKIFALQNLVSEDVN"
     gene            55125..56948
                     /locus_tag="OE968_000217"
     CDS             55125..56948
                     /locus_tag="OE968_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCP7217534.1"
                     /translation="MNLSTGNQKVSRLKKKEKPKDFKKTFKRIFMYFKKDKKITRFIF
                     LLVIIDSIISTVIPYTIGKVVDIIDIDTYSKSIFLKGIIILLSFYIIEFSVKLSKGIC
                     TARLSQSIVREMRSNLFLKFKNLPITFFDKSSTGDIMSRVTNDVDNISTGISNSLVQL
                     ITGILNILMTFIMMFVLSPILTFCSVILIPIVMFVSNFIAKRTRVFFKQQQVELGKLN
                     AHIEEMISNINVVKSFNYERKSVNDFKEVNDRLLNISLKSQIYTSLLMPIMNVISNIG
                     FATICIIGGILASKDIITIGVIASFLSYVRQFTRPLNELANLFNTLLSAIAGCERVFE
                     IIDEQEEQEVHNMFKSEINDNKDGNLNSHFVKGEIELKDVSFSYDSKKKILDNINLKI
                     KSGTSNAIIGETGSGKTTIINLITNFYHIDEGSIFLDGKDIYSINRNYLRTCFGVVPQ
                     EGYIFNDTVMENIRYGNLEATDEEVIYASKIANAHKFIVKMREGYSTVLSDRGEDLSE
                     GQKQLISIARAVLKNAPILILDEATSNIDIATEAKIQEAINNLTYGKTSIIIAHRLST
                     ISNCDNIIVLENGRIVESGNHKELIKLKGHYYRNILLTQGK"
     gene            57066..57611
                     /locus_tag="OE968_000218"
     CDS             57066..57611
                     /locus_tag="OE968_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH peroxidase"
                     /protein_id="HCP7217535.1"
                     /translation="MKKFVCTVCGYIHEGDAAPAQCPVCKVGADKFEEMKGEKNWADE
                     HRIGVAQGVDEEIIEGLRANFVGECTEVGMYLAMSRQADREGYPEVGEAYKRIALEEA
                     EHAAKFAELLGEVVVADTKENLRVRVDAEYGATDGKLKLAKKAKELGLDAIHDTVHEM
                     CKDEARHGKAFLGLLNRYFGK"
     gene            57871..58479
                     /locus_tag="OE968_000219"
     CDS             57871..58479
                     /locus_tag="OE968_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dienelactone hydrolase family protein"
                     /protein_id="HCP7217536.1"
                     /translation="MVDNLIKYIHKSYVAIVVLHEIYGINSFIEDVCQKYYKYGYDVF
                     CPELLGEKRVFPYSKVQEAYDFFINNVGFDIYKKVEKLINDLKSEYKYVFVAGYSVGA
                     TIAWRCSEDSFCDGIICCYGSRIRDYMDVIPKCPTLLVFAKHDSFDVDSISYQLSRKQ
                     NIQIEILDANHGFIDRYSNNYSDIQTKVFTIKEKSFLSKYLA"
     gene            58806..61703
                     /locus_tag="OE968_000220"
     CDS             58806..61703
                     /locus_tag="OE968_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HCP7217537.1"
                     /translation="MKAFKKHFLILSLIFLLIISCFNNILCFADESENSKKIRVGYCD
                     DYGIISSSKEHSYTGYGYDYLREISKYTRWEYEFVKGSWEECLDRLEKGEIDLLGPLQ
                     KNDERNKLFNFPKLNSGYEYSVLYTKDSNNNMFYEDISSFKGMRVAVLRGNFHNIAFE
                     KYREENNFSVEYIYCNSIDELIESVNEKKADAFVCGSIINAKGMKIVSKFSVEPFYFA
                     TAKYKPNLVKELDYALKELKINDMYYELELYKKYFKREVNNSIAFTRQEMNFIKANPK
                     LTMVYDSEWSPVEYYDKESNSFKGISSNLMSIISKKCGIKFEYIKTKNYNESLDYIKS
                     GKANMLCGSINENDKAKRFNMKLTNPYINIPMIMVGKLDTNLNNDLNIALTSSYKSID
                     SYIEKSFENAKTTSYKSIESCLNAINEGKANLMILSSYQFDELLREGKSENLSVISVL
                     DTSYGMRIGVSNKTDPILVSILNKSIDKITEEELSDCIYSNTIDKPYKVPFGVIFKEY
                     SIQIISFVCILFLIAIKYIIYNKKKKEDYLKKIAYTDPLTGADSIDKFKINSNKLFAK
                     NNPEEYALFYIDVDKFKYINDMFGYDMGNDTLIHISNTIASELKEDEIFARVSADHFV
                     LLIKYKTDDDIKTRLNNIYNKVQILSNPKINYYKLILDCGIYKISKSDNDINTIMDRA
                     NTARKTIKGGHKNSFAFYDKEMHKKILKEKEIENSMVDALNNGEFIVYFQPKYSLSDY
                     QIIGAEALVRWDNPQKGLIPPIEFIPVFERNGFIVNIDFYVFEEVCKKIREWMDEGQK
                     VVPISVNLSRMHFVNSNFIEKFKLIVDKYKIPTRLIELELTETAVLDNIEGLLDTMNN
                     LKEKGFVISMDDFGTGYSSLNLLKELPVDILKLDRAFFTEKDESNNEKIVISNVIKMA
                     KELKMKVISEGVETISQVEFLKQIGCDMVQGYLFSKPMPVKEFEKIAFKKE"
     gene            62024..62236
                     /locus_tag="OE968_000221"
     CDS             62024..62236
                     /locus_tag="OE968_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HCP7217538.1"
                     /translation="MMPLILSNTGEEVVIKKISGSDKTRTFLNSIGFVVGTNVKIVSK
                     IDGNLIIDVKDTRVALDKKMASRIII"
     gene            62249..62470
                     /locus_tag="OE968_000222"
     CDS             62249..62470
                     /locus_tag="OE968_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HCP7217539.1"
                     /translation="MNRLKDIKCGETVKVKKLEGEGATRRRIMDMGITRGVNIFIRKV
                     APLGDPIEVTVRDYELSIRKSDAEKIIVE"
     gene            62570..64726
                     /gene="feoB"
                     /locus_tag="OE968_000223"
     CDS             62570..64726
                     /gene="feoB"
                     /locus_tag="OE968_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HCP7217540.1"
                     /translation="MSIKIGLIGNPNCGKTTMFNGLTGSSQYVGNWPGVTVEKKGGKL
                     KGNKDVEIVDLPGIYSLSPYTLEEVVTRNFMLDDKPDAVINIVDASNIERNLYLTTQV
                     LELGIPTVIALNMMDIVNKNGDKINIKELSEVIGCPVVEVTAVKGQGIMEAAEKAVEL
                     ASSNNKLNFKLPFVDESKDAIEKIEKIIEEKTPYIDVETRWLAIKLFERDENVIQKLD
                     ISKTILNSIEEITRNCEDELDDDSESIITANRYEFISSIISSIIKKNRKGKETVSDKI
                     DKIVTNRILALPIFALIMWGVYYIAVSSLGTIATDWTNDVLFGEIIQGNVSNFLASLN
                     VAEWLQGLVVDGLIGGVGAVLGFVPQIMLLFLLLSILEDCGYMSRVAFIMDRIFRKFG
                     LSGKSFIPMLISSGCGVPGVMSTRTIENDRDRKMTIMLTTFIPCGAKIPIIALFAGAL
                     FGGASWVAPSMYFLGIAMIIICGIILKKTSLFAGEPSPFVMELPQYHIPSAKGVLIHM
                     WDRGKAFIIKAGTIIFVACGVIWFLQSFNWSLQMVDAGDSILASLGNIVAPIFAPLGF
                     GNWQSSVATVTGLVAKENVVGTFGVLFGISDATEQDPTLLASVASMFTVASAFAFMAF
                     NMLCAPCFAAIGAIKREMGSWKWTWITLGFQTLTAYIIALLINQVGSLVLGTGGSIAG
                     AIISIFIAVAVVFVVLTYSNKNMKKEKMGKLSYMKN"
     gene            64752..64904
                     /locus_tag="OE968_000224"
     CDS             64752..64904
                     /locus_tag="OE968_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HCP7217541.1"
                     /translation="MATFIIAAIVVVLMALAVMYMVKNSKKNGSSCGCGCSGCSSSKS
                     CHSAKR"
     gene            65084..65794
                     /locus_tag="OE968_000225"
     CDS             65084..65794
                     /locus_tag="OE968_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AIM24 family protein"
                     /protein_id="HCP7217542.1"
                     /translation="MFKFDVTNELMCIARGSGKFFAKKGAMVAFKGNFNFEKLLLGPS
                     NGGGLGRALLGHVQRSLTGEQMPIMVVEGEGEIYLAQNAYHVDVISIDPGDSIYVESE
                     NLLAFSEQLNYSVKLIGSGVISQKGLFTTHLVNKTGQNQDVAIITDGNPLILEGPCCV
                     DPDALVAWTGREPYPKVSKLSWKTFIGQTSGESYHMEFVEPGQIVIIQPSERLSGLKT
                     DSTPSDRMSSGGLRLGID"
     gene            65879..66649
                     /locus_tag="OE968_000226"
     CDS             65879..66649
                     /locus_tag="OE968_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCP7217543.1"
                     /translation="MFEKIHKRLKGYYIFLIILILWKIVCVLGIWSSYILPPPEIVLD
                     TFIKMIYDGSIFLNVYASVRRILIGFLISSLMAIPLGVLFGVNKKMYEYFKPLFEFMR
                     STPPLALVPMLILWFGIGEESKIIIIILASFFPIFLNTLKGIKNCDNKLIEVGKSFNL
                     SKKRIFYKIIIPNSMLDIVVGLSLGLGYSFRAIIGAELIAASSGLGYLISDGKDMSRT
                     DVVLVGIFVIGFLGILSDYLFSKIITKFSKGKQVDLNG"
     gene            66642..67373
                     /locus_tag="OE968_000227"
     CDS             66642..67373
                     /locus_tag="OE968_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCP7217544.1"
                     /translation="MVRSGFLLENIYKKYLVDNKEHLVLDNISLNISSEEITVILGES
                     GCGKTTLLRILAGLENATSGNIYFFNNDKKCTPKVGMVFQESRLMPWLNVSENILLHT
                     EKDNRNKVDLDKYLKMMKLEKFKNSYPNELSGGMAHRVSIARALSFNPDILLMDEPFA
                     ALDYFTRRKMQKEVVNIHKNTKKGVVFVTHNIEEAMEIAKKIIVFSKNKRIKQFSVED
                     EYNRDLTKNYYINLKKEILRELGEF"
     gene            67407..68366
                     /locus_tag="OE968_000228"
     CDS             67407..68366
                     /locus_tag="OE968_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NrtA/SsuA/CpmA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HCP7217545.1"
                     /translation="MTSLIMVLVGTVGCSTTNDKKDEPAKKEASLPKEINLTYVKSPL
                     NVPSILEKKDDLFGKEFKKDNIKVNFHELTTGPEQTQALAAGELDFLHALGGTSAIIA
                     ASNGVGLKITNIYSRSPKGYMLITNNDNIKSIKDLKGKKIVGPKGTILHQLLIAALAK
                     EGYTIDDVEYVNMDIPSAASALESKSADVAMLAGPVALKTINSGAKMIVNGEGLVSGI
                     IVTAVSDDFAEKYPELVKRFMKVHEETLKYMNENKDEVMDVVSKEVGLSLDETKEMYS
                     WYDFSSKITDKDIKELEDTQEFLMSNGMQQKKINIKDMLYNQN"
     gene            complement(68464..69060)
                     /locus_tag="OE968_000229"
     CDS             complement(68464..69060)
                     /locus_tag="OE968_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3793 family protein"
                     /protein_id="HCP7217546.1"
                     /translation="MSCCNSQFCCKNKIESSYIKWLLEVLGPVFLGSKPAEIINISFT
                     DVNREEKINDIYKYLYKCKKIDFIVIDKEKKGLKILFVNKKALSEKLKCKKTVNFLKF
                     LGYKQNTNVNAYLEHLVDKLKSDVFPDEIGIFLGYPLKDVIGFMGYSNYEVSMIKYWK
                     VYGDTKQSEDTYSKFLLHRKKMRKLLDYISVDKIVSCF"
     gene            69306..69905
                     /locus_tag="OE968_000230"
     CDS             69306..69905
                     /locus_tag="OE968_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7217547.1"
                     /translation="MKLKRTLFVGLALVLAIGITACTKNNEKPSENTGKNPNESVNNN
                     EGYMNYYSTSYNDYIAGLNRYSIYDTPESINNQFKDKEYPGNEKYLSDVKAAYKDSRD
                     KIQSFVTSLKKDGKTEDTELKKMNDDLIAEGERLVKDIDKRIEKLDKVSDEDMKKGQN
                     DFIKLVHGTEDVGNDIGSGFRKMIKDMNDRLGITGNNKK"
     gene            complement(70075..70542)
                     /locus_tag="OE968_000231"
     CDS             complement(70075..70542)
                     /locus_tag="OE968_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7217548.1"
                     /translation="MENNTIKADDIINYCLSNLDDVLLMNSWGERAIYYNPNGILKRG
                     VYVLTIKEKDSNHDKGSLVSRPNVYRVNIGLKKETFIEMFGYIPKRPGVGQIVDMDFD
                     FTKLDTIMPHPIYSWMGWICVLSPTEKTFENFKTLIGESYNFAKQKFKKRKNK"
     gene            70653..71597
                     /locus_tag="OE968_000232"
     CDS             70653..71597
                     /locus_tag="OE968_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YafY family transcriptional regulator"
                     /protein_id="HCP7217549.1"
                     /translation="MSRAERLIELMITINAKRSFTAGELAEEFSVSKRTILRDLQVLE
                     SIGFPLYSKVGAAGGYHVLKERILPPIAFSESEVKSIFFAYQSLEYYNDLPFEQETIS
                     VLKKFLNCIPNDIQYNIENIRRKFVFWTPDRHCSTPLLKELFNIVMNESTIKIEYSSK
                     QKNSVRTIVPIGLYAMNGLWYCPAYCIKSASIKEFRVDRIVKILSIENLSSKKYKVLS
                     SIHDYLKNMEVGTDYHIKINLTDEGVKRCETEFLLARGLKILSKGGYIDMYIPKSTLN
                     WVAEYFLTFGKNATIIEPIELKHLVKSKVLELYNHHCI"
     regulatory      71887..71993
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            72099..73064
                     /locus_tag="OE968_000233"
     CDS             72099..73064
                     /locus_tag="OE968_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HCP7217550.1"
                     /translation="MISIKNVNKYYGKIQVLKDVSIEIESGEIFGIIGHSGAGKSTLL
                     RCINGLEEYQEGSVLVSDKEVKSLNEKQMRDLRKELGMIFQHFSLLERKTVFDNVALP
                     LECFGYSKAEIKKRVLELLEVVGISEKKNDKPRNLSGGQKQRVAIARALALNPQVLLC
                     DEATSALDPNTTKSILSLLEDINKNLGITIIVVTHQMEVIKQICGRVAIMENGEVLEV
                     GDTEEIFLRNTKGLRKLIGEESIILPKGTNIKILFPKDISNEAIITTMARELNIDVSI
                     IFGKLEQFKDDILGSLIINISDKSGEQVKQYLTSKGIRWEEMINE"
     gene            73057..73713
                     /locus_tag="OE968_000234"
     CDS             73057..73713
                     /locus_tag="OE968_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCP7217551.1"
                     /translation="MNSLIDFLTTLFPNALLQTLYMVIVPTIVATILGFILAIILVVT
                     KPDGLKPNSTINSALGFIVNIFRSFPFMILIVAMIPITRLIVGTSIGETAAIVPITIG
                     AAPFIARIIESSLNEVDKGLIEAAKSFGATKRQIVFKVMIKEAMPSIVSGITLSIISI
                     LGYTAMAGAVGAGGLGNIALIYGYQRFDTAVMVYTVIALIILVQIIQGVGNLAYKKLK
                     "
     gene            73749..74540
                     /locus_tag="OE968_000235"
     CDS             73749..74540
                     /locus_tag="OE968_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011987989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HCP7217552.1"
                     /translation="MKLKKLLSVALVSAIAISAVGCSNKEDKKILVGASSNPHAKILE
                     VAKPLLKEKGYDLEVKIFDDYVLPNTALDEGSLDANFFQHIPFLEETVKEKGYKLTYT
                     SKVHIEPMGFYSEKVKSLDELKDGAVIAVPNDATNGARALKLLAKNKLIEVKDGELIT
                     KKDITKNPKNIVIKEMNAEQLPTVLKDVDGAVINSNYALTANLNPTKDAIVIESSDSP
                     YVNIIACRENNKDSDKIKALSEAMNSKEVKKFIQDEYKGSIVPAF"
BASE COUNT        29658 a         7908 c        12502 g        24694 t
ORIGIN      
        1 atctaaaata tatggaatag gtagagattc attaatgtat tatgaagaaa taggcattct
       61 aagaccagtt agagatataa atggatatag aatgtataat atatcagata tatggaaatt
      121 aaatttaata aaagaattta gaagcttgaa ctttccaatg aagaaaataa aagaatacct
      181 agatgacaga agtatagagt ctacgaaaaa tattttaaat gaagaactcg atttaattga
      241 taaaaaaata gctgaattta taagccataa ggaaaatatt ataaaaagat tgagttcaat
      301 tgaaagtgta attcaaaata caaaaataga tgagatagag gttgtatata tagaaaaaag
      361 aaaagcttta gaattaaatg ctgatataaa gagggatgaa gacttcgatt ttttaattca
      421 aaaacttcag aaagaatatg aagatagatt taatatactt ggaaacaaca atattggttc
      481 tgccttttct actgaagcaa ttaataaagg tatatttaat gagtttaaat ctgtattttg
      541 ttttctggaa agtaatgaga aagtatataa tatagttttt gatgaaggat attatgtaac
      601 tttaaattat actgggagta attctaataa taagatatat atggagaagg tgtttaaatt
      661 tatagaagaa aataattata agataattgc tgaccctata gaaatctata agatagatat
      721 acatgagact ggaattgtag aggagtttgt aacggaaatt caagttccta taactaaata
      781 gctatatttc aatggattag atggtaaata gaatgaaaaa atgttgattt gccactgtgt
      841 tataaaatcg gtagcaaatt atattttaaa ttataagata gcatgaaaaa ataattgttt
      901 agggggttat aaatgtgaaa tgttctaatt gtggaagtgt aaatattgaa aagggaattt
      961 taacaactgg tggcatatat gctgaaacta ttggattaaa atatagagga gatggaaaat
     1021 tagataaagt tataaataaa acttttccag tacaatctac tatatattca gatttatgtt
     1081 tagattgtgg agaaatagtt agaacctata taaaggataa tactgatagg aattggtgta
     1141 aagataagaa atagaataat ttttgaagta tattaatatt tgaagttgaa ttttattaaa
     1201 gatacaagtg aaaaagtata aatgggaaga aattgttata tggaagaaaa ctttgcatat
     1261 aggggagatt agttttttaa tataataaca tttttaaatg tagataaaac taaaaagggt
     1321 tctctagaaa acaatttcta tttaattata cttacttacc aataccatca cttgatgtaa
     1381 acaagattct actacatttt ctccgtactc tagtataaaa tcatctagct gtgtatctat
     1441 aaaatcacaa taatcatata aactactgat ataagcagtt aacatgtgtg tacatttatc
     1501 catttcatct ctaaacatat atattactat ccccctaaaa aactttcata aaacaaaaag
     1561 aacaatatct ttttggcaac tggctgacat aactcatagt ttattttata agcgttagtc
     1621 cctatagctt tgcgtcacta aatttctcta gttttgccga tttagtttta ttctacaact
     1681 aaaataatac actaggataa gttattgttc aacatacttg tcagaaaatt gaaatattta
     1741 acagtatctt aacaatatga aatctatttt tcactcaaga aataaactat acatgtagaa
     1801 tatttaataa aaattatatt tagttttgta ttgaagtttt tgtattaaaa agtttagttc
     1861 acaagagtta cttggctaga taatagatga acaaaaatat cttgaaaaaa tatatatgaa
     1921 tggcaaaaaa caagggatga attttatata gactcatccc gtaattattt atatattgac
     1981 cttgattaaa tatattatta tttttaagct tcaattttta tattatattt ctaaagtttc
     2041 tataagagga ttatcgctaa ataattttaa taaatttgtt tttttatatc ctttaggtaa
     2101 cttagtatat ataactactt ctaaccaatc cccatcaagg cgtttaatat tcatgtttat
     2161 aatttcaata ttagattttt taaatttacc ttcaatatat tctatggaat cagtgctgtt
     2221 agaaatttta agagaaactt gctctgctgt agggagtttc atccatttcc tatctctatg
     2281 aagtgttatc tgtacaataa caataatgat acttgaaaca ataccaacta agtataatcc
     2341 agagccaatg gcaagacctg taccagctgt tgcccatata ccagcagctg tagtaagacc
     2401 acttactgat tgatttctaa taaatattaa tccagcacct aaaaaaccta taccactgac
     2461 aacttgtgct gcaacgcggg ctgggtctag accaatacct ggagtaccca ctatatcatt
     2521 aaatccatac ttggaaacaa tgattataag tgctgaagct aatgccacta taaaatgagt
     2581 gcgtattcca gcttctttta gtctattctt tctctcatat ccaattaaag ccccacagaa
     2641 accagcagta atgattcttg ctatatattc aaattgaatc aatatatgat ggttcattta
     2701 tctagcaccc ccttctatat aatattatat atactataat actacatttt ttatgtgaat
     2761 atagtaaagt ttaaaattta tataatagtt atatatgaat ataaaatgta taaacgtata
     2821 ttatgtatat aaaaatgata gaaagcatct aattttaaat gattaaagag caagcttaaa
     2881 taaatcaaac ttgctctttt aacatagtgt atgtttttat ttgtgatagt tagataaaaa
     2941 tttatctgtg ttttttacat ctgcaaaact gttctgtagt gatgccatga atacttgatg
     3001 tacagtattt gcattaattt ctatattatt ccaagataaa ttcttcgttg tacatgcatc
     3061 gcttattaga gttatgtcgt atcgaagttt ctttgctgtt cttacacttg tatcaataca
     3121 catatggctc atcattccac agattactag attagtaata ttttttttct caaggatact
     3181 ttgcaaatct gtttcaaaga aactatctgg tgtgtgttta gttataattt cttcattatc
     3241 tagtggaaaa acaattttat ttatttctga accatgagta ttaggaagaa aaaaagaagc
     3301 tgttttatct gttgatatat gctgtatatg aataactggt aaattgtttt ttctaaaaaa
     3361 cagtagtatt tttttagcat tttcagcagt ttcttctgat tgaaataatt cacattttcc
     3421 atttttaaaa taatcatttt gaatatcaat caatattaaa gctatagaca tgattatacc
     3481 tcctatttat ttttattata atactattgt aaaaaatgta aattacttac tttttggtat
     3541 gtataggatt acttattgta gcaaattcct ttattatcta gaatttcttg ttgaccatgt
     3601 tcaagcatat attcgattcc tatttcttgc attatttcca ctgcttttaa cattttttta
     3661 ccacgattag taagaaaata ttcaacatgt aatggatatc cagcagaact tattttatca
     3721 ataatcccaa aatcacgtaa ctcttttaat tgttgaatca acattttttg atttattcca
     3781 taaatattat gttgcaattc agaaaatgtt ttattagatt gtcttaattc aaatataagg
     3841 atagttttcc attttccttt gattatgtca tgtacaattt caagaagaca tgtatattca
     3901 gctcttattt tcatagcata tcacccccag taaaatgata ataaattata tcacttgtct
     3961 tgtgatatga caaatatata tgaactgtat ataaatttta tgttttatta agttctaaat
     4021 ttcttctatt gtagttcata tttagtacat aaataattag taagatataa gtaaataaat
     4081 atataacatg actatagaaa tttaacttta aaataactta tgataattta gaggaggaat
     4141 atatatgaat atatcaagaa aagctatgaa aataatagaa ttagcacaaa aaattgcaaa
     4201 taagagaggt atttcagtag aagaagcttg gagtgaagca gtaacagaat ataaaaataa
     4261 atacgaacat attgcataga tatttaaaaa tttagaatat ttggtagaat ataatgattt
     4321 taaatgatac tataaattat aaggtatatc attattaaca tagaaggagg atatctgctt
     4381 gattgtaaaa atagataata ctttagaaaa agaattttgg caatatgtat cacatgaaga
     4441 aagtttaaat ttattcataa ttggatacgt tgagaattat ggatttagct ctcaatatca
     4501 agatatatgg tctcaggtag aagatggaaa tataacctct ataatattaa aaaataagtc
     4561 aacacttata atttatagtt ttaaaaataa ttttaatata ggagaaatga agaatcatat
     4621 aaaagattta gatgtagaaa gcataagtgg aaaaaaatgt gtaatagata gactaataag
     4681 taaatacaaa gatttttatg aaaaactaga taataaattt tgtgtattaa aagaaataaa
     4741 agaaatagat ttttccaaca tgaaggagta taaaatagaa aatgctcagg aaaaagatat
     4801 tgatgaaata ggaaaacttt taaataggtc agactataaa gtaagtaaaa attacataga
     4861 agaaagaaaa gttcatttaa aagagggaaa tgtaagagca tattttatta gaaatgatga
     4921 tactatgatt agcactgtgt caactggtat ggaaactagt tttttggcaa tggtggtctc
     4981 tgtaagtaca gataaaagat ataggggaaa aggacttgca agttatatgg tttacaattt
     5041 gagtaaagaa ttgttgttag aaggaaaagt tccatgtctt ttttataata atgatgtagc
     5101 aggtaaaata tatcataata taggatacaa agagataaat gaatggacaa ttctttttaa
     5161 atagctataa aaaataaaaa actctatcga gaattaaagt atttataaat aactatattt
     5221 ttactataat tcatgataga gtttttttaa atttatgata ctatttttta ttatttaaat
     5281 aatcaagtgt tttaagttta taaccttctt tttcccaatg tgtaagaacc tcatctaata
     5341 tctcagtatt tgttgatgaa tttggatgca gtaaaactat tgcaccagga tgagttcttg
     5401 aataaatttt gtttttggca aattcatgag taggttgttt cttttcatac caatctacat
     5461 aagcaaaact ccaaaatatt gatttatatc ctaaatcttg tgtatatttt aaagattgtt
     5521 cgctaaattt acccattgga ggtctaaaat acttaggcat ttcttttcca gtaacatctt
     5581 tgtatgcttt ttctacactt gtaatttctt ctttgaattt ttcaaaatct gtaatacctg
     5641 ccattgatgg atggcttttt gaatgattac aaactaaatg tccttctttt tccatacgct
     5701 ttattaactc tggattgctt tttatataac tttcaactac gaaaaattga gctttagcat
     5761 tgtgtttttt aagcgtatct aataattttg gagtgtttcc actttcatat ccagcatcaa
     5821 atgatagata tataactttt tcattgggat ttcctacata ataagctccg tattttttaa
     5881 aaaaatcagc ttcttttata ggtgatggct gtttaccatc ctccctaggg ttaaaatacc
     5941 aatcatattc atgtgtgtcg agtgttggac tagaaatttg agtttttgtt ttatctaatg
     6001 atttaaaatt tatactagca attccaaaaa gtattagagc aaatgctcct atcataatgt
     6061 atttttttag gctatctttt ttcacaattt cacctcttat ttaaaattta aagtatattt
     6121 cttataatat agtttgaata tttatagtta aaaatattca catatacaaa taataaatga
     6181 aagaagttta ctgtaagata taaagttgat attaattatc ttaaataaag tgtatataaa
     6241 tgataaaata taaagagaaa tgattgtaaa taagttaggc tggtttaact tgaagggata
     6301 taaaaatgga taatataata agtgtattga atgatgttgt ttttttagat atagaagtta
     6361 gtggattaga ttgtttaaat tcagaaattt tagaagttgg agctgtcaag gttaaagact
     6421 ggaaaatata tacctatgaa tcattaataa aaaacaaatt tgaggtacct gtagaagtat
     6481 tctcagtatg taaaaattta gataaaaatg atttagaaat agctaatgaa atagaactgg
     6541 tggaagatag acttgtaaat tttgtagaag atagtttcat tatatgtcat gatttaagtc
     6601 tgaaaaaaaa gtttcttgag tatcatatgc caaagttaaa aaacaaattt attgatttaa
     6661 ttgaattagc agttatttta gaaccatatc ataaagatta tagcttagaa tacttaaaaa
     6721 atactttaac aaattgtaat tctaaagtgg aaaatagagc tttatcagat gctattgata
     6781 taataaatat tgtaaattgc cttttagtaa aatttaataa ctatgaaaaa actactttgg
     6841 agccattgag ttttaaaata aattcatatc ttaaaaaatt taatcttcca acatgggaat
     6901 ggagcaaatt tttagaagag gcaaattatg atttatcaaa taatataaat ataaaaaaag
     6961 aatataatat atttgactca aaagaagaaa agaagaagga aagagaaacc ttaaaaattt
     7021 taaatgaaga agaaaaaaat tatgaagaat tattaaaata caaaactatt tgggagaata
     7081 aagaaggatt tacatatgaa tatagacctg gtcaatatga gcttactaaa acaataagag
     7141 agttgtttag aaatagcgaa gatgaagaaa aaattgcatg tatagaggca ccaactggta
     7201 taggtaaaag tgtaggatat ttattgcctg caatattaga ggctagaatt aataaaaaaa
     7261 gattattaat ttctactgac acaaaggaat tgcagataca attaataaat aaagatattc
     7321 caaatgtgtt agattctttg ggtctaaatg gaaaagtaag ttacggatat ataaagggaa
     7381 aaaataacta tatttgtata gatagactgg aagcatatat agatgattat gagtctcaaa
     7441 accctactaa aggagaaatt ttatctttaa tatttttgaa gagattagtt gaaggtggca
     7501 agtatggaga tatagaagaa ataaattatt tagtgtttga caacttcaag gaaataagta
     7561 ctcacttaag aaatgtaagt tgtgacccaa atatgtgcag acctaaaaaa tgcaaaaaag
     7621 attgtttata taaaaacaga atagaagaat taaaagaaga acatataaca gtagtaaatc
     7681 attcactatt agctaaatgg ccatataagg atgaaaaacc tttagaaaat ataatagtag
     7741 atgaagcaca taatttgact gaaaaaggat atgatttctt ttcaagcatt ataaattcaa
     7801 agtctttaag gtatttatta caagaaattt atccttacga gtttattcaa aatagtagct
     7861 ttatatataa aaaatatagt agaaatatga gaaaaataaa ggcttttgat aaattttata
     7921 atgtattaaa aattggaaga gaagataaac aaaaaattgc tagaagtata aatctcatta
     7981 ttgaagagat agattcaata ttaaagtttg gtaattgtaa tgaatataat aatgtaagta
     8041 attataattt aagatgggaa ctgaatttgc aaatagacga aattgtggga aaactaaaaa
     8101 aggatggtat agatactgaa ataagttata gagcctatag tgaaaagata aagttgagtt
     8161 gtgagaaaat aataaaaaat ttagtttcaa taataataat aatttatagg aatattgatg
     8221 atgatagtat agataaagaa gcagatatat ataaatttgg aaaggcaaag acaagagatt
     8281 tagaggatat aaagattata tttgaaatct ttttagagta tgatgaaaag gatgattatg
     8341 caaggatagt tgaaattgat aagaattata atgactttga atttcgagta gtgccattaa
     8401 aaatagcaga tttatttgaa gaaaatattt tatctcaatt agaaaaagga atatttttat
     8461 cagcaacttt gagtttatct gaaagtatgt cttattttaa aaatacatta ggaatagaca
     8521 gagttaagaa tgtggaaaag attatagaac caatttttga ttataaaaat agagtctctg
     8581 tagttggatt ttctgatatt tgtgagtaca gaaattctga atttccaaat gagatgagta
     8641 aaattatatc taatatatca aagattacag aaggtcatac attagctctt tttaatagta
     8701 aagatagaca agaaaaaact tatgaaatat tgaaaaaata cttacatagt tttaacttag
     8761 aaatttatgc tgataaaaag gggattagac accttaacga tttaaataga aaatgtgtag
     8821 tacttggctc aaaaggatgt tttgaaggcg tagacattcc aggggatggt ttggtttgtg
     8881 taactttaga caagcttccg aatctaaatc caaaagaccc tttgtatttt actataatga
     8941 agaagtatgg tatagactac tatactataa attatcctca aatgaccata aaggtaaagc
     9001 aagctatggg gagaatttta agaagcaaat atgactatgg atgttttgtg atttttgatg
     9061 taggaactaa tataagtgtg ttaaagagat tagagaaaga tttacacgat tgtaaaattt
     9121 caaaggttaa tagcaatgag ttttatactt atataaggcg acatttaaat aaatatagaa
     9181 gtttaatact aaaatctgtt atatttgata ctataaaagc gttgaatgtt gatgctaaaa
     9241 tggataacaa tgatgttgat aaggatatta taaaaaaaga tataaatgaa aatataagac
     9301 aaagagctgt aaaaggagaa gtgtaccata ttgatattat aaaaaaagat atgaaagtaa
     9361 aatattttga tagaaactat cttataaatt tagatatatt tatgagagaa gaagataaaa
     9421 attaagagtg ggagtgatat atttggcaaa acaaaagttt tatgctgtga aaaaaggtaa
     9481 aaatataggt gtatataata catgggatga gtgcaaaaaa caagtaaatg gattctcagg
     9541 agctgaatat aagagttttt ctacttttca agaagctaaa gaatatattg atgggtcaga
     9601 aaaattgagt tttcaagaag ataaggagtt tatagaagca tatgtagatg gaagttatga
     9661 acattcagta aaaatgtatg gttcgggtgt tgtgatttta aaaaataatg aagttataaa
     9721 aacttatagt gaaaaaggaa aagagaaaac tttagtaagt atgagaaatg tagctggaga
     9781 gatagaggct tctaaaattg caatgcagta ctgtattgac aataatgttc aaaacttgat
     9841 tttatacttt gactatgaag ggattgaaaa gtggtgtact ggagtttgga aaacaaataa
     9901 agaaggaact atagcatata aaaatttcta tgacagtatt aagaataagc ttaatgtaaa
     9961 atttacaaag gttaaagctc attctggaaa taagtataat gaggaagcag ataaattagc
    10021 taaaaaagct attggtgtat aataaaaaaa tatttataca taattacatg gtataagagt
    10081 atatctaaat tcctacttta taattaaaca acttgtaatt aaacaacttg taattaaaca
    10141 acttataatt aaataaattt tgattaaaaa agcagattgt attatgaaaa aataagtatc
    10201 taatttataa acaattaata atagtattaa ttagatacaa cttatttaat ataataaaat
    10261 ctgcttttta tataactata aaattttcct acattctatt agaattgccc ataaatacct
    10321 tcaagttctt cttttaatac ttcagggtca tttataccaa tagacatggt tctagccagt
    10381 atatttgctt ggtcataagt tgatgtccat gagaatacac cacctagaca atttctaaga
    10441 acatattgag tttttaagaa tattgataaa gcatcatcat atgacattgc aaaatctcca
    10501 tccttaacta aatatggaac ttgagcagta ttatcaaatc tatattcata tccattttta
    10561 tttatataat cccttctaag ctcatcataa gttcttgtta tagtagcacc taatcttcca
    10621 taaaatggta taccaagaag gattttttca gaaggcattc cagcattctc aagatttctt
    10681 accattgcat caacactata tcctggcaaa gataagtctg aatcaaaaag atttgcttga
    10741 tgttttctac catttgggcc tgtttcacct gctgtaaaat cataactcat aagattaaaa
    10801 taatctatta taggagctat tttatctatt tcagcacttg aatttatata tcctctatct
    10861 cctgttccag ctacactaag ccatttatca tctcctataa catctcttat ggcagttagt
    10921 aagagtgtaa agttttctct atcttgaggt cttgatgtta ttccagatgc actacttcca
    10981 ggatattccc agtctatatc tattccatct aaagcatatt catttatcat ctgattgacc
    11041 tgtcttgcaa aattatatct agatgtaggt gttaatgctg catcagagaa tccttcagct
    11101 ccccaacctc caatagctac aattactttt aagctaggtt tttcaccttt aagagcaagt
    11161 aattgattta aaaatctagg ataaggaata aacaaatttc cagactggtc tatctcagca
    11221 aaagcaaata taactgcatc taatagttga gcatctacat tagttggatt tccaagaaca
    11281 tattctgcta caattggatt tatatctgga cagtttgcat tttcaactat tggattgtat
    11341 gggtctgtta tttgtggtct aactaatttt ttagaatctt ttaaagtttt catagctatt
    11401 tttttagtat ttttttcgct agtataatcg tagtttttat aattatgttt atagaaatct
    11461 tcataactac tatcttcttt gttatagcta gaatttattt tgtcacaaga ttcatcttta
    11521 tcatagttaa aattcatttc atcacaagac ttatctttaa acttatcttg tttggagttg
    11581 tgaactttgt tagtattttt agtatgtttt ttctcatgat tgcaatcatc tttaatatca
    11641 gtcttgtgtt cttgtttaca gtcaagagct ttgttcaggt agtcatgatg ttcatgttca
    11701 cagttacatt cattttcaat gtttttagta tgttcttttt tccagctaca agtattatca
    11761 attttcttgc tcacttcttc atcattataa ttatctggta caaaacataa gtaccagtcc
    11821 atacatgaat atttcttatt acaactgtta actctatttt ttaattcctt atagttttta
    11881 ggataaggta aaatcactgg cattccagga aaccagtttg caggagtaac tatattatct
    11941 ctatcactag tctgaagtgc atctactatt ctaagtattt ctggaatatt tcttcctgta
    12001 gttagtggat aataaagaat cgttcttaga atttgattat tatctataat aaatacagag
    12061 cgaacagttg atgtatcact cattggtttt gatatcatgc cgtataactt ggcaattctc
    12121 atatctctat cttctataat aggaaatgga atttctacac ctgtaagtaa agaaatatta
    12181 tacatccaag ctaaatgtga actgttacta tcaacactta gaccaattag ttctgtattt
    12241 ctttttttaa attcgtcata atatttagca aaacataaaa attctgtagt acaaactggt
    12301 gtaaaatcac caggatgtga aaataaaaca atccaattac ccttatagtc agagagtcta
    12361 ataggaccat ttgttgtatt ggctttaaaa tcaggagcct ttgaccctaa acttggcaaa
    12421 tttggcatgt aaatcacccc tcaataaatt atcatttatt ttattctatt aattaataca
    12481 tattagtgtt actattttat taaaagttaa gtaatcctta tgtcaaaaaa agatatttat
    12541 taaaaagatt taatattttc ctaatataaa tgacaatagt aattgctatt tttttactaa
    12601 tttggtatag taatggataa ggggtagtgt caattttagt gattatacga ggtgagtgga
    12661 ttgaaaaaaa ttctaagaat tttagttatc tccatgatga tatgttttgc aatgactttt
    12721 gcattagtgt taataaattc agttatggga gtacatatag gattggatta ttactttttg
    12781 atgggaagtg tgcttacagt ttgtttaaca attggaattg ttttatgcaa tgctagaaaa
    12841 atatttgata gcaaagctat acacaagaca agaacgaaaa ctgtcagtaa taataaaaaa
    12901 caaaagagtc attctaggga tataaaaaga aagatatcat aatttatgta aaggaaatat
    12961 ttatgtataa aataatgatt gataggtaaa ataaaaacac gatttaactt gtgtttttat
    13021 tttttttcaa gaattatgat ataataacca ataagaaatt tagtttacca taaaatataa
    13081 agattattaa atggagaggg aactataatg aattttagag atttatttga gaaggctgta
    13141 gattttattg atgaaaaaag gaaatctata gttgcgattt cattatcaac attaggtgta
    13201 attgctttga taatagtatt tttcttaagt agtaacgagt ttagtgtagg aaatgaagct
    13261 aatgagttgt taaagattat agagaaaaga cagtattcta tagctgttga ttactacaca
    13321 agtatagaaa aaaagttttc tgattcaaaa atggaaaggt ttaataagtc tgtttctaaa
    13381 aaaataaata aattgctatt aaatagtggt gataaatatt tagatggaga cataagtcaa
    13441 gaaagtttta ttggattaat aaataccgtg aaagaattaa acaaaataag tatagatgtg
    13501 gatgacttat tagctcaagc tgatagagtt agagaaatgt ataaagaaga aaatactact
    13561 tatgatattg ccattaacta cataagtact gtttcaatat taaatggtat gggtagtaac
    13621 ctagatgtat acaaacagaa tatagaaaca atcaaagagt ctagagatgt ttatgactca
    13681 gcagtaaaag accaaaaagc atataagtat tatgaagcta ttgaaaagta taataaagta
    13741 ttaaaagaag atgaaaagta ttacagtatg gctcaaaatg ggaaagaaca atgtattgaa
    13801 gaaatgtatg attactatat aagtagagct gaagaggcaa atacttctgg agattatgaa
    13861 agagcattac aatatattga gtatttaaaa gacgattatt cagatgatga aaaggtacag
    13921 agtttagaaa aaaaatataa aaagaattta tcattgtata ctttaacatc tgatgacatt
    13981 ataaatgtaa tagctaaaaa aagtggcaaa gacaaggcaa atctatctat aaattcactt
    14041 ccacaaatga taaaaaataa taaatactat tatgctgaag tatatgagta tgataaatta
    14101 ataaatgaag ttttggtaag tgcaaaaact aaagatttat attcatataa agatggtaaa
    14161 aaagattaca aagtagatta tggtgatgga tactttagaa tattagaaga tggaagttat
    14221 caatttggta ttacaaaaga taaagctaag tttgtgttaa ctaatactct tgatgaaaaa
    14281 gaaaataagt ataaaaagat tgagatatta gatatagaga aagcagatag atatgtaaaa
    14341 agtaaaaaga gtttagaaga attgtttgga aaatataaaa atatttatta ttatgctgta
    14401 gtaaataaag gcttatttag aggcaaagaa gtttatgcta ttaatattta caatgaaaaa
    14461 atatatgcca tatcagaaaa tggactaaat gaatattaat taataatatt aaattaatat
    14521 ataattaaaa agtttttggg gttttaaggc gcattatgta gtaatataat aatagggata
    14581 tataaataat tttattgtaa ggagaagtat gggatgagta atgtgaacaa aaagctagtt
    14641 atagctattg gagctgtagc attagtagta ataattttta taggcataat gtgcatgcaa
    14701 tttaaagggg agaaaatagc aaaaaacaca tatgttaatg gagtaaatat tggaaaatta
    14761 actaaatcac aagcaaaaca ggaattagct aaaaaataca aattagagaa tgttgatttt
    14821 aattacaatg ataaaagctg gaaagtaaag agcaaagatt taaatttatc tactgacctg
    14881 gataaaacag tagaaaacgc atataattta aatagaaaga gtgctttctt tggcaatcta
    14941 tcaaaaacta tttcagcaaa ttttggcaaa aaaagcaact tagtagttgc gataaattat
    15001 gataaaaata aattaaaagc agaaatggaa aagatagcta aagaaataga tgtagatgta
    15061 aaagatgcta cacttgatat aagtggtgaa aaagtcaagg ttataccaga ttctgatggt
    15121 cttaaaatgg atatttctaa gagtatggag aattttgata atcaaactaa aaaaggtaac
    15181 tataaaaatg agttagtagt aaaagctact ccagcaaaag taaaaaaaga gcaacttgct
    15241 aatatagata caaatttagg tacgtattca acaacattta aaacttctca aataaataga
    15301 agtataaaca taaaattagc aacagataat ataagtaatg tattacttat gccaggagaa
    15361 actttctcat ttaataaaca tacagggaaa agaagtaagg aaaatggata taaaagtgca
    15421 cctgtaataa tggaaggtga gatggaagaa gattatggtg gaggagtttg tcaagtttca
    15481 tctacgttat acaattctgt gctatacgca ggtttagaaa ttgttaatgt aaaaaatcat
    15541 actataccat caagttatgt tccaaaagga agagatgcaa ctgttgcaga tagtggaata
    15601 gatttcttat ttaaaaataa tctaaagcat ccagtttaca taaaaaatta cgtttcagga
    15661 aatcaaattg tttgcaatat atatggaagt gcagaagata aacaaaatat aacaatatca
    15721 acaaaattag atggcgtttc acaaactaca atgaaaagag ttaatgaccc tacaatgcct
    15781 aaaggtaaag aaaaagtaga caaaagtgga agaaatgcat attctgtatc aacatataga
    15841 acatttaatg atgcaaatgg taaaaaaatt aaaactgaaa aaatagctaa ttcatattat
    15901 cctaagaagg aaggtattat attagttggg actatggaac caaaaccaga ggaaaaacca
    15961 aatacagacg aaaataagaa taatcaaaat acaaacaatc aaaacccaaa taatcaacaa
    16021 aaaccagaaa caccaccaac tgataataag cctaatgaga cacaaccaca accgcaagct
    16081 taaagttctc aagaatagga tttatgtaga gtaataaaaa atataaatct aaataggagg
    16141 gattactttg aatttaaata atataacgaa ttacgttcaa agtatttgcg agaatatttc
    16201 taatgtcttg gatgtagatg ttactttagt tacaaaagat ttaactagga tagcaggtac
    16261 aggaatattc agaggtaaaa taggagagac aatatcagag aagtcagtgt actctcttgt
    16321 tttaaaagat gggaaatcct atgttataaa taaagaaata gaagagaact gtaataaatg
    16381 tgcaaataga gaaaattgta aagagttagc tgatatatgt actcccgtta aaatgggaga
    16441 gcatatactt ggaatcttgg gtatagctgc gtttaatgaa gaacaaaaag aaaagatact
    16501 ttcaaaagat aaggagttaa ctgcttttgt aaggagtatg tctgatttaa tatcttttaa
    16561 actagatgaa ctttataaac aagaagttaa gactatagat gaccttgaga gggaagctat
    16621 agaaaatgcc ataaagaaat atggaagtaa tacagaaggt atgaaaaaag tagctgaggc
    16681 attaaatata ggtatagcta cactctatag aaaagtaaaa aaattcaaca ttaaaagtta
    16741 atagtattga aaaagaggta acctttttat gaaaagaaga ggattacctt ttttattatg
    16801 agaatggtgg aaaaatatgt atagttttga cttgacatat taaatatgtt atcttaaata
    16861 tatattttag agtggaggtg agtattattt tagttaaaga tataaaacaa gacatagaaa
    16921 gcatgcctag aaaaatttta gatatatctt tgatagaaga taataaaagt gatttgactt
    16981 tttttaatat agaagaagaa gacggtgatg aaacattaaa agcattaaaa cagagttatg
    17041 tgactacaaa ttataaagaa gaaactctat taaacttgca aggagcttta aattcaaagt
    17101 cagatacaac gtctaaggag ttaaaattag aatcatataa aagatataac aatgcattgg
    17161 atttagcata taaaaattat ataactagtg ccattaatat ggttaataaa gctctggaga
    17221 taaatcctaa agacattgat atactaaatc ttagaggtct tttaaaatta ttaaaatgtg
    17281 attttgctaa atcatttgag agtttttata ctgctttatg ttatgaaaat aatcatatat
    17341 ctagaaaata tgtaaatcta atttcatctg aagattttaa aactttttta ggaagataca
    17401 atcattctat aagatttata aatgaagaat taaattatga gtcaatacat attttagaga
    17461 acataattga agaagaacct gaactaatag agccatatgt aattttatct ttgttatatg
    17521 ataaactagg taatgtaaaa aagagagaag gatatttaga caaacttaaa gagctagata
    17581 aagataatcc tgtatttgaa aaaaatgaag aagaaaaaga agatacaagt aaaaaggaag
    17641 aaataaaaaa agtaaaaaga aagaaaagta ttttgccata tattatagtt ggctgtgttt
    17701 taataggtat ggggatatat ttgattcaaa gcaaaaagag aatagaaaac ttgaataacc
    17761 aaataagtag taaagaggaa aagttaagtg aaactgataa aaagttagga gaaacgagta
    17821 aaaaattaga aaaaacgaat aaggaattaa atgaggttaa aaataaagaa ccagaaagag
    17881 agataactgt agctgatgag gaagatttat attatcaagc tctaaattta aagaaaaaca
    17941 aagaatatga aaaagccata gataatttta aaagtgtagt ttcttctggt aaaactaaaa
    18001 aatatatttc tgagtcaata tatcaattag caataacaaa taaattatta ggaaataagg
    18061 atgaagctat aaaatattac aaaaaatata taaatactta tactaaaaat gaccagtatt
    18121 atgatgattc atattacgag ttgggtatgt tttattatga taatggcgat ttaaaaaatg
    18181 cacaacagac tttttatagt ttgagaagtg aagttccaga cagtatgtat aacaattcaa
    18241 aaataaaaga aattttaagt gaaaaatagg tttatatagt taagtttttt gaaacaacca
    18301 agtatgtatt ttattaaatt aaaataaaaa taaatttaaa aagagattgt gtcaaattat
    18361 aactttctat tttaaagaaa gatatttgct tgttgataaa actacaaata tatgatttga
    18421 agcaatctct ttaatttttg gaggtggaaa atgaaagttt tcaatcaatt ggtaataatt
    18481 ttatctatct gggtaatagg agagtatata agttccttta tacaaggaat tatacttatt
    18541 cctgggagta tagttggtat gctattatta tttctactac tacaatttaa agttttagac
    18601 ttgagtagta tagaaaatgt aagtggattt ttcctcgata atatggctat attttttatt
    18661 ccagcaggtg tatcacttat aaagtcatta gacctaataa gggaaaatgt attagtgctt
    18721 ttattagtca tatgtttaag tacactaata gtaatgtata ctactggaat tattgtggag
    18781 aaaatgataa aaaagaagga agaaggacaa aaaaatgtat aatgtattac agacaccagt
    18841 atttggtata atagtaacaa tagttttttt caatttagga agatacattc aacgaaaaac
    18901 aagtaatcct atatgtaacc ctttattaat tgcaatcgta ggaataatat tgtttttaag
    18961 catatctaaa atcccttatg agaattacaa gataggagct gatagtctaa atttcttttt
    19021 aggtcctgtc acagtagtac ttgcagttcc actttataaa caatttgaat tatttaaaaa
    19081 gcatatgttt gagattattg taggaatagg ttgtggtata gtgatttctt ttgtatctgt
    19141 attgataatt ggcaaaatag ctaattcaga tgtaagtata ataaattcac taattccaaa
    19201 atctataaca acaccaatgg gaatatcttt agcaaattct ttaaatggtg tagaatcaat
    19261 aacagttgta gccataattt ttacaggtat ttttggtggt atggttgctt ctacagtatt
    19321 caaactgggg aatataaatc atccagttgc taaaggaatt gctcttggaa catctgcaca
    19381 tgctttagga actacaaagg cttttgaact tggagaaata gaaggagcta tgagtggtgt
    19441 ttctattgga gtctctggta caattacagt aatactaatt ccaattataa tgaattttat
    19501 ataaaaaata aaattaagat gagtaccttg aatacttaaa acaaaataaa ataaaaaaaa
    19561 tttaaaataa aaactgaacg aaaaaaatgc aaataatgaa ataaaaaaat catgtactga
    19621 aattataaaa agaaaaattt catttaggaa ttaattataa agagacaatt actaaacttg
    19681 aatttgctaa aataaaataa attactgcta aaatagatat ttagaaaaaa atactataaa
    19741 tttactatat tgcaagttaa ataataagca gtatcatatt atgctagaaa aagtttcatt
    19801 taaggcataa atgagatgat ttgaacgttt ttaaagatta gaatataaaa gattgcacta
    19861 gacatatatg aaaaagataa tataatagat gatgtaatag atgacagttc aagaaattat
    19921 aaaaaaaatt tatttgaaat attatctatt acatcaggaa taatatatgt aagagtaagc
    19981 ttttaaaatt ctaaagattt agaaagattg aagggagaaa gaaatgagtg aagttaagaa
    20041 taccctacaa aaacatccag ttttaagata ttcaacaatg ctatttggga tgttgatgac
    20101 atctatagga ataaatgggt tcttaagacc agcacatctg cttagtggag gtgctacagg
    20161 tatagcaaca tctataaact atttgacaaa tataaatgta ggtttattaa catttttaat
    20221 caatattcca atatttatct tagggttcat ataccttgaa aaagagtttt gtatttcaag
    20281 tttggtaaat atgattgtat tttcattatt attaggagca actcaggaaa taagtaatat
    20341 tatacctata catgatatat tgcttcaaag tgtatatggt ggtatattat ctggtttagg
    20401 agtcggagtt gtatttagaa ctaggtcttc tcaaggtggt acagatataa tagctgcaat
    20461 actaaaaatt aagaagaata tagaaatgaa agacactgct ttagcaataa atggcttgat
    20521 agtacttaca ggaagttttt tatttgggtt ggatttagca ttatacactc ttataggtct
    20581 atttctaaat gcgtattcaa tgagttttat taaagatgca atgaattacc aaaaatctgt
    20641 tatggtaatg tcaaatgaag tcgatttaat agcagaagat ataatgaaga gtttagttag
    20701 aggtgtaact tttttagatg cagaaggtgc atacactcat caaaaaaaga agattatata
    20761 tacaatagtt tcatcaaatg agataccaaa gataaaagat atagctttga agtatgataa
    20821 aaaggccttt atatctgtaa atgatgttac agaagtaaag ggaagagggt ttaaagcaaa
    20881 agatttatag aaaattttac aagctgggag tttataatgt aaatttgtat attatatctc
    20941 tcagcttatt taaatttagt atacgaaaat aaaggtttta ttaatgattt gtgtatcact
    21001 ttaaaagata tcattttaaa attaaaattg aaaaaattac ttaatatgta gaaaacatga
    21061 ccactattag gatataataa atttaataga tttagtaaaa tacctaggaa taacgttgga
    21121 ggaatggcat tatgaattta tctaaagaat atgttaattt gtatgataat tatttgaaat
    21181 atataaatga agtaaacaaa gagattagaa gtataaagaa catgaagaaa cgtgttttaa
    21241 aaaggggcga ttttgctccg gaaaatgaag tattagaatt ggaaggaaaa acaatacgcg
    21301 atatagatga tgtcgataca aaaaaaccaa aaaataaaat ctataaattt tcaaatgggg
    21361 atgtatatgt agggaaattc ttagagggaa agatggaggg gaaaggctca tatacttttt
    21421 ttgtagatga aggaacagtt atggagtaca taggagaatt taaagaagat aaaaaaaatg
    21481 gaaaaggaaa ctttatattt tcaaatggaa atgaatatat aggttatttt gaggaagata
    21541 tgatgagcgg tattggaaat atgttatata gtagtaaaga tgaatatatt ggaacttgga
    21601 aaaacggaaa aaaagatgga aaaggtattt ataagtggag tgatggatgt atatatgcag
    21661 gtgaatttaa aggtggaaag atggaagggt acggtatttg ctataatagt aaaggggaag
    21721 tactttatga aggagaatgg aagaataatt tgattcatgg taagggaact tatatatggg
    21781 aaaaaggtaa aaagtatata ggtgaattta tgcatggtaa aaaacatggg caaggaactt
    21841 tttatctaaa taatgaattg gtttatgaag ggacttggaa atttgataag ccatctatat
    21901 ttgatagaac attagatgaa atattttcct tgagactgta gctttatcta attagtagat
    21961 aaagcttttt tctaatactt actgtaaata ggtatgaatg atattgatta gtatacacta
    22021 tcaatattaa cttaataaat gcaatattaa aaaattttga ttgattttaa gaaggagaga
    22081 tatattgaag agattaattg ctttagtgtt agtagtactt attgttttat tttatagtcc
    22141 tgaattatta aaagaaggat atgatttaaa agaaaagttt tttcaaagtg aaatatggaa
    22201 tgaattttta gacaaaataa atataaatga taattctaag aaagataaaa aagaaaaaag
    22261 tcaaaattta caatcaaata atactgaagg ggagaactta ggagagtcag atataaagaa
    22321 ttttgaaaaa ataagcttag gagataattt aagctatgtt ttatcaagta tcggcaaacc
    22381 tggtagaatt gatattagtg aatatggttt tgattggtat gtatataatc aatatggaaa
    22441 agaatttgca atggttggac ttgaaaatga tgaagtagta gcactttata gtaattctat
    22501 taattcatgt gaaaatcaag atataaaact aaatcaagat agacaaacag tgagaactaa
    22561 gattacacca ttaaaatata agagaaaagg aaataccaga tatataataa actcagaaaa
    22621 tcaatatgat ataataagta aggaaggtaa gtatattaca attttctacg atattcatga
    22681 agaaaataga gtttgttcat atttaataat tgataaaagc actgaagatg agtttaaaaa
    22741 tttatatcca gatgatagcg aagaacttaa aaaatgtttt gaacttgaag ttatagacct
    22801 tgtaaatagt gttagaaatc aaagagggtt aaactcattg agatacagtg aacaggcaac
    22861 tttgagttca agaaaacata gtgaagatat gagagataat aatttttttg accatgtaaa
    22921 taagaagaat gaaactccat ttgacagaat gaaaagagaa ggtatagtat atacttcagc
    22981 tggagaaaac atagcagcag gacagattaa tgcaatatat gcgcatgaag cttggatgaa
    23041 ctctgaagga catagaaaaa atattttggg gaactataat aatattggag ttggagtaat
    23101 atttggagga agctataaaa catattacac tcaaaatttt tataaataac taaaatattt
    23161 gaaaggaagt taaaaaatga catcatggaa aaaaaagaca gtatataagt gcttaatagc
    23221 agtagccttg ttttgtggaa tagtgttaat atctaatttt agtaaagttt ctgctttgat
    23281 gatggatact aatggaaatg ttttgattaa acatggttca agggaaaaaa agctaatagc
    23341 aattaccttt gatgatggtc ctcatcctaa agaaactagt caagttttag atgtattaaa
    23401 gaaatacaat gtaaaagcta ctttttttat agctggaaaa catgcaaaat ggtataaaga
    23461 accattagta agagcaagta aagaaggtca cgagatagga aatcatactt tcaatcatcc
    23521 tgatataagt aatttaagtt ctagtcagat agaagaggag attgttaagt gtgaagacat
    23581 tttgaaggaa gtaactggga aaaaacctac attatttaga ccaccattcg gaagttatag
    23641 agaaaaagac ttaatagaaa ttgcaaaaaa gcatgactat aaagttgttt tatggacagg
    23701 tgtagatgtg aaagattgga aaaatccagg agctaatagc attgcagata aaataattaa
    23761 taaagtacaa aatggagata taatactttt gcatgattat gcaactaatg atacagttga
    23821 agctttagat atgtttattc caaaaatgat tgaaaaaggt tttaaatttg taacagtttc
    23881 tgagttgata aaataatttt taggggggag atttacagta tgattcttat gatagacaat
    23941 tatgattctt ttgtatacaa cctagtccaa tatatagaag aattagggga agcagttgta
    24001 gtaaaaagaa ataatgaaat caaaataagt gacattgaag aactaaatcc agaggtaatt
    24061 gtgttatctc caggaccgtg ttctccaaaa gaagctggta tttgcataga tattgttgag
    24121 cattttaagg ggaaaaaacc tatactagga atttgtttag gtcaccaaac tattggacat
    24181 gtttttggag gagatattat aaaagcacaa cagcctgtgc atggaaaagt atatagtatc
    24241 aaccatacta ataaaggagt ttttagggga cttaaaaatc ctttaaatgt cactaggtat
    24301 cattcactaa tagttgactc caatacagtt ccaaaagaat tagaaattac agcaattact
    24361 gataaagggg aaataatggg aattaggcat aagaaatatt taatagaagg agtacagttt
    24421 catccagaag ctattttgtc agagtatggt catgaaatgc ttaaaaattt tataacagaa
    24481 gctagagaaa gggtacatat gtaatatgat aagagagata aatactaaat taaattcttt
    24541 tgagatattt actattttta gaaatgaaca tgacagtttt atattagata gtgctatgga
    24601 taaagaaaaa ttgggaagat attcttttat aagtagccaa ccatttaagg tattaaagta
    24661 taaagatact gatgaaaatc ctttagaagt tttaaaagaa gaactacata agtatagggt
    24721 tgtaaatgat actaatcttc catttgtagg aggtgctgtg ggatatttat cttatgattt
    24781 aggtaattac atagaaaatt tacctagaac tgctgtagat gatattgaga tgcctgatat
    24841 gtattttgga ttttataatc atgtaatagt tatagaccat cttgtgcaaa aaacttatat
    24901 agctactcca aacatagata tcgaattaga agaaaagata atagatgata tagaacaaag
    24961 aatattaaaa gaagagaaaa aaggtataga tagcatatgt tatgaagaaa aagaagtaac
    25021 acctataaga cttaaatcta attttacaaa ggaagaattt aaaaatgcag ttcaaagtgt
    25081 tagagagtac ataagacaag gagatatata tcaagctaat ttaacacaaa ggttcagtgg
    25141 agaaacagaa cttacaagct ttgaattgta tagggactta agaagattta gcccagcacc
    25201 atttggggca ttcttaaact ttgaagatgc acatatatta tcaaattctc cagaaagatt
    25261 tataagatgt gttaataaga gaatagaaac tagaccaata aaaggtactc gtccaagagg
    25321 gaaagataaa gaagaagatt taagacttca acaagaactt agaaatagtg aaaaagatag
    25381 agctgaacta cttatgatag tagatttaga aagaaatgat attgggagaa tatctaaaac
    25441 tggaagtgtt aaagttccag agctatttgt aattgaacca tatgcaaatg taaatcactt
    25501 agtttccaca gttgtaggtg agttaaaaga tgataaagat gctactgatg taataaaagc
    25561 aacttttcca ggggggtcta taacaggagc acctaagatt agagcaatgg aaattataga
    25621 cgaattagag ccaacgcaaa gaaatgtata tactggttca ataggttata taggttttaa
    25681 tggtgatatg gattttaata tagcaattag aacaataatc aaaaatgaca aaaaagtcta
    25741 ctttcaagtt ggaggaggaa tgacttggga ttctgaccca gatgaagaat atcaagaaac
    25801 acttgataaa gctaaatcca taatgaaggc tttgagggga tattatgaag aataatgtag
    25861 gttttgatag tagtttaagt aaatttggaa ttggtttgtt tgaaactatt agagttaaaa
    25921 atggaatagc agtagattta gatatccata tagaaagaat gctaagctca ataaattgtt
    25981 tggatttaga tataaactat aaaaaagatt tcttgataaa tgaaattgtt acatatataa
    26041 aaaaagaaaa tgtcattaat aaagcactta gaattactgt ttttgatgaa ggttataata
    26101 tatctattag ggatattcca tataatcaag agacgtatga gaaggggttt aaattagcta
    26161 tatctccaat agttaggggg aatagtttaa ttcatagaca taagactact aattattttg
    26221 aaaacatata taccaaaaat atcgcaaata agactggtta taatgatggt atatttttaa
    26281 attcagaagg tgtaatatta gaatgttcta tgagcaatat tttctttata aaaggagaaa
    26341 gagtgtacac tcctagtgat agattaccga tattaaatgg aataataaaa aaaaggatta
    26401 tagagatttg tgacgaatta catatagagt tgatagaaaa tgaaattaat atatcagaaa
    26461 ttagtagttt tgattttgtt tttgtcacaa atagtcttat gggcgctata aaggttacag
    26521 aaattgacaa aataaaattt aataaagaaa atgttgtttt tgataaaata gtgaagttat
    26581 tagaataaat taaaatatta acaatttgtt ggagacaaaa gatgataggt tgtatttatg
    26641 aagtatacaa tgaagagatg actaaaataa tagaaaacca aaacactttg gctgtatatt
    26701 tagtgggttc tagtaaagat gtagatttta ctctttatga tgtagtgata aacgatattg
    26761 atgtgttcgt ttttgtaaaa gaaggggaaa aacaagagag aatactgttt aaaaaaaagg
    26821 gaatagaatt tgatgtaaat tacttttcaa aagatggtgt aaaaaaatta ttatcaaata
    26881 gggaatattt ctttgtgaaa gaaatgaaag atgctaaagt actgtttgat agggagaata
    26941 tatcacatat tataaaagat ataagtagag atatttactt agaaggacct agtaaaatgt
    27001 cattagagga aaagtctttt ataaagcaag atattggagc aaaaatattg aatttaaaaa
    27061 ataaagaaaa atttgatgtt tttgaatatc attttttgac gaatttatat ttaaaagata
    27121 taataattgg gtactttaat ataaatgata aatgggtacc aaaagacaaa aaattgctaa
    27181 aagttttaaa aaaagaaaat aatgagcttt ttgaactagt gtcaaaagta agtgaaaatt
    27241 atgactatca aagactttta gatgtttata attatatttt taaagaaatt gagacaaaag
    27301 aggttataaa actaatcttc tagtcacaaa tcaatggggg gagtttaaat gaataaagtt
    27361 gataaagaaa agatacaaca tgcagtaaga gaaatactag aggcaattgg ggaagaccca
    27421 gatagagaag gtctaatcga aactccaaat agagttgcta ggatgtatga agagatattc
    27481 tctggtctta gtgaagaacc aagagaccat ttaaaagttc tttttgcaga tgaaaaacat
    27541 gaagagttag tattggtaaa agatattcca ttttattcat gttgtgagca tcatctagtt
    27601 cctttctttg gaaaagctca tattgcttat ttaccaaaag gaggaagact tacagggctt
    27661 tctaaacttg ctagagtaat agatacattg gcaaaaagac cacaattaca agaaagaatc
    27721 actaaaaatg ctgcagatat aataatggaa gaattacaac cttatggtgt cttagtagta
    27781 gtagaagctg aacatatgtg catgacaatg agaggcgtaa aaaaaccagg ttcaaaaact
    27841 gttacatcag cagtgagagg aatatttgaa aaggacattg cgtctagagc cgaggctatg
    27901 agtttgatta ctatgaagta gtaatttatt atagatataa tcatttattg agataaaatt
    27961 taatttaagg gagtgtcatt aattgtgttt gattatggta aaagaactta tataatggga
    28021 atattaaatg taactccaga tagtttttct gatggaggag attttaataa cttggacata
    28081 gcaatacaac atgcaaaaga tatggttgac caaggtgcag atataataga cctaggagga
    28141 gagtctacac gcccaggtca tagctatgta gactcagacg aagagctaag aagagtaatc
    28201 cctgtaataa aaaaacttaa acaggaattg gatataccaa tatcaataga cacttataag
    28261 gcagatgttg cagaagaagc attaaaatta ggtgtcacta tggtaaatga tgtttggggt
    28321 cttagaaaag ataaaaatat ggcttctgta ataggaaaat atgatgcaga agtgtgtata
    28381 atgcataatc aagatgggac aaactatgac aaagatataa tggagtcaat aaaagacttt
    28441 tttaaggtaa gtatagaaat ggcaatgagt tgtggtgtaa aaaaagaaaa aatagtactt
    28501 gacccaggtg taggatttgg caaggatttt gaacaaaata ttgaagtatt gagaagatta
    28561 aatgaattaa aagatttagg gtatcctatt ttgcttggga catccagaaa atcagtaata
    28621 ggaaaagtac ttccagttga gcctaaaaaa agattagaag gtacaatagc tactactgtt
    28681 cttggtataa gagatggcgt agatatagtt agagtacatg atgtttatga aaatttaatg
    28741 gcagctagaa tgactgatgc aatatataga aagtaggtat aatataatgg ataaaatatt
    28801 acttagtaat ctaggattct atggatatca tggtgttctt aaagaagaaa attttctagg
    28861 tcagaaattc tttgtcgaca tggaacttta tattgattca agagaagcag gtcttagtga
    28921 cgatataaat aaatctgtaa gctatgccga ggtttacaat gttgttaaag atattactga
    28981 aaataaacaa tttaatcttt tggaggcttt agcggaaaat attgctgaag aagtcttgaa
    29041 taaatttata cttataaatg gagttatggt cagagttaga aagcctgagg ctcctgtaaa
    29101 tggtatttat gactattttg gtgttgagat aaggagaaca agagatgaat aaggcttatt
    29161 tgggaatagg tactaacatg ggtgatagat ttgataattt atcaagagca tgtgaacttt
    29221 tgaaaaatag tgattctata tataaagtaa aagaatcaag cttatacgaa acaaaaccat
    29281 ggggatatac agaacaagca gattttctaa atatgtgtgt agaaatagaa acagagtttg
    29341 aaccttatga gttgttagaa tattgtcaag aaatagagag agaactacac agagagagaa
    29401 tagttcattg gggaccaaga actatagatg tagacgtact attttttaat gatgtagttt
    29461 ccactgatga aagactaaca atacctcatc caaggattca agatagagct ttcgttttga
    29521 taccacttat ggatttaaat gaagaactta taataaatga aaaaacaata aaagaacatt
    29581 taaacctcct atctgctgaa gaaagagaag aagtaaagga gcttgtaggt tatgaaagaa
    29641 aacctattta ataataattc aaagatagag ataaatacaa ataacaaaaa gataactgta
    29701 aaaaaagata aacttataat agctggacca tgtgcaatag agagttatga gcaacttttg
    29761 gagactgcta aatttgtaaa aagtcaggga gcaaatattt taagaggtgg agcatacaag
    29821 ccaagaacat ctccaaattc atttcaagga ttaaaaaaag aaggtcttga aatattaaaa
    29881 gcggttaaag acgaagttgg tatggctgtt attacagaac ttatggatgt aagagatatg
    29941 gacgaactgt atagtataag tgatataatt caaattgggt caagaaatat gcaaaacttt
    30001 actcttttaa gtgaagtggg aaaacaaaat aaacctgtta tgttaaaaag aggaatagct
    30061 tccacaatta ctgaatggat aggtgcttct gaatatatag caatagaagg aaatagtaat
    30121 attataatgt gtgagagagg tataagaacg tataatgatt atactagaaa tacattagat
    30181 ttagctgcag tacccattat tcaaaaggaa acaggtcttc ctgttgtggt agacccaagc
    30241 catgccactg gagttagata tttggtaaaa cctatgtcac tggcatcttt tgcatgtgga
    30301 gcagatggaa taatggtaga agtacatcct gacccagaaa atgctttgtc agatggtgct
    30361 caatctcttt gctttaatga atttgaagat ttaatgaaat caattaataa ttattaaaag
    30421 aggcaagagc ctctttttta ttcgtaatcg ttgctaaggt aaatttataa gttataattt
    30481 gatagttaga ttatttaata taaataaaga tttaatattg atagaattaa tataaaaaat
    30541 aaaaattttt tgattaataa gaaggatatc aataaaaaaa gtcgaattgt gtatattgag
    30601 tgattgacaa atttagaata tagtgtagaa tagaaatgtt aacacaaaaa attacaccag
    30661 aaggtgataa tatgaatgat ataaaagaca ttattgaaga aataaaagct agatgcgata
    30721 tagcaagtat aatatctgaa tatatgaata taaaacaatc tggagctaat tacaaaggat
    30781 tatgtccatt tcatggcgaa aagacacctt ctttttatat aaatacgtca aaacagattt
    30841 ataagtgttt tggttgtggt gaaggtggag acgtaataaa ttttgtcatg aaaatggaaa
    30901 atttggattt tatggatgct gtaaaaattt tagcaaataa atgcggtata gaaattaaca
    30961 ctaacatgaa tgaagaaact aggattaaaa tagaaaaatc taagaaattt caagatattc
    31021 atacggaagc agctagattt tatctttcaa acttattggg aagcaaaaat cttgggtatg
    31081 aatatttaag aataagagga ctagatgata aaattattaa gaaatttggt ttaggatttt
    31141 ctttggattc atggaattca cttatgaata ctctaatcag taaaggatat aaaaaacaag
    31201 acttattgga gtgcggtcta attgcaaaaa atagagatgg aactaattgc tatgataaat
    31261 ttagaaatag agttatgttt cctatattcg attatagagg aaatataata ggatttgggg
    31321 gaagagtatt agacgattct ttgccaaaat acttaaattc tccagacacg ttaattttta
    31381 ataaaaaaca gaacttatac ggattaaatt ttgctagaaa aaatttagaa agtaaaacta
    31441 tagtcttagt tgaaggatat atggatttaa tttcgcttta tcagtatggt ataaaaaatg
    31501 tagtagcaac ccttggaaca gccttgactg aacaacaagg cattttaata aagagatatg
    31561 cggacactgc tattatatct tatgattctg atgaagcagg aataaaagcg actttaagag
    31621 ctatagatat acttactaaa ttaggtatca atgtaaaagt gttagactta aaagatgcta
    31681 aagacccaga tgaatttgta agaaaatacg gacttagtga ttataaaaaa gctatggatg
    31741 tttctactca ctacataaaa tataaaatag atcatcttaa aaaagaattt aacattcaaa
    31801 aagatgaaga acgagtgaag ttcgcaaaag aagcttctaa aattataaaa caattgacaa
    31861 gtcctgttga aattgatttt tatacaaagt atttaagcaa tcaaatagat attaatgtcg
    31921 agtctataaa gagagaagtt tatggtaaaa attacaataa gccatataat aacaaaaatc
    31981 aaaagaaaat agaagaaaaa gtaattgaaa aagtcgaagt cagacaagac ggaaaacaat
    32041 tagttgaaga aactctaata aaaataatgt tagaagacaa aaaaattaga gaaatagcgt
    32101 tacttaaagt agaagaaagt gattttttat tgaaagaaag taaagaaatt ttaaattaca
    32161 tgattaaaaa tcaagaattg gacaaaataa ctattgacaa attgaaaagt ttaaacatat
    32221 ccgaagaata cttaaaagaa ttaaattcaa tttctttgaa tagtataaac ttagagaaca
    32281 caaaagaaat agaaggaata ataacaaata tcagaaaaaa ctcattagaa gagcaaatta
    32341 atagcttgtt gagagaacaa caagaattag aaaataataa tgatatgaaa gaggtagatg
    32401 gtagagttat ggaaattgct ttaaaaatag ttgagataaa taaaatttta aagagcttgt
    32461 agagaaagga ggtttgagtg tggaaaataa atcgaataaa aaagagttaa aaaaggttac
    32521 tgctaagaca ttaatagaaa aaggaaaaaa gcaaggttct ctgacacttg cagagataat
    32581 ggaagctttt tcggagactg aacttgataa ggatcaagta gaaaatcttt atgagacttt
    32641 aggaaatttg ggaatagaaa taacagaaac aaaaaactat aaagctgata tagatttttc
    32701 ggttgctgat gacgatttaa gtataggcca cttagatgaa gatgcagagg caatttcaca
    32761 tgatgactct tctgcaatag aaatagaaac tgtggattta tctttaccaa aagggataag
    32821 tatagatgac cctgtaagaa tgtacttaaa agaaatagga aaaattcctc tacttaaacc
    32881 acatgaagaa gtagaatttg ctagaaggat gcacgaaggt gatgagatag caaaacaaag
    32941 gttagttgaa gcaaacttaa gactagttgt aagtatagca aaaagatatg taggaagagg
    33001 tatgcttttc ttggatttaa tacaagaggg aaatttaggt cttataaaag cagtcgaaaa
    33061 atttgactat acaaaaggat ataagtttag tacttatgca acatggtgga taagacaagc
    33121 tataacacgt gctattgcag accaagctag aactataaga ataccagttc atatggtaga
    33181 gactataaat aagctaataa gagtatcaag acaactactt caagaacttg gaagagatcc
    33241 aaaaccagaa gaaattgcaa aagaaatgga aatgacagaa gataaagtaa gagaaataat
    33301 gaaaatagct caagaccctg tgtctttaga aacaccaata ggagaagaag aagatagcca
    33361 tttaggtgac tttattccag atgatgatgc tccagcccca gcagaggcag cagcatattc
    33421 tttattaaaa gaacaaatag aagatgtact tggttcatta aatgatagag aacaaaaagt
    33481 attaaagctt agatttggtc ttgaggatgg tagagccaga actcttgagg aagttggaaa
    33541 agagtttgat gtaactagag agagaataag acagatagaa gcaaaagcac taagaaaact
    33601 aagacatcca agtagatcaa aaaaacttag agattattta gactaaaaag atacatcatt
    33661 gatgtttttg tgataaatgc catgagataa gtgatatctc atggctattt tgtagtaaag
    33721 atttaatttt atttttgtag ttatttcagt ctaatatcta taacttggat taaatcctat
    33781 aaataaaggg aattgaaagg agaattatat ttgaaattaa cagatagatt attgaaaata
    33841 gcatcattag tgtcagatgg taaaaaaata gctgatatag ggacggacca cggatacata
    33901 ccagtatatt tgttaaaaga gggaaaagta ccatttgcag tgctagcgga tgttaataaa
    33961 ggacctcttg acaatgcaca taaagaagtc atacagaaca atcttttaga taaagttgat
    34021 ttacgattgg gttctggtat agagatactt gaaatagggg aagtagaaga agtgataatt
    34081 gctggtatgg gtggaatctt gataagtgag cttctcgagg ctaaaaaaga agtagcacat
    34141 aatgtagaaa aattaatatt acagccaatg caagcacaag aagaacttag atattacctt
    34201 ttaaacaacg gatatgaaat tttagaagaa gttttagtga gagaagattt tagaatatat
    34261 gagataattg ttgccaaata tacaggtaaa aatactataa tagaagatga gatatattat
    34321 gaggttggaa taaagctttt agaaaacaaa gattctcttt ttaatgattt tatagaaaaa
    34381 aagataaaga catatagttc tatagttaat aaattagaag ggaaaaatgg ggaagctata
    34441 gataagaaga gaaaggaaag cgaagttgca ataaaaaaac ttgaaaattt aataaaataa
    34501 ataggaggta tatatgctat taaagagtct aactagaaaa attgaaaaaa agtatcctct
    34561 aaacttagca gaggattggg ataatgtagg tcttatagtt ggagattttg atatggatgt
    34621 aaaaaaggta ttggtatctt tagaagctaa tgaagatgtt attgatgaag ctatatccaa
    34681 aaatatagat ttaattgtga cacatcatcc ttttatattt gggaaaatta ataaaattaa
    34741 tagtggagat ttaaaaggca gacttatcca aaaacttatt aaaaatgata tatcacttta
    34801 ttctatgcat acgaattttg atatagcatt tgatggtcta aatgactatt ttatggaaat
    34861 tatggaattt ggtaattcaa aggttttaga tataactaaa agcgaaaatt tgtataaatt
    34921 agcagtatac gttccacata actattcaga tgaacttaga aaggttttaa gtaattcagg
    34981 agcaggtcat atagggaatt atagtgattg tacgttttca atagaaggtg aaggacaatt
    35041 taagccatta gaaggctcta atccgtttct tggaagtgta aatgatatag aaactgtaaa
    35101 tgaagttaaa attgaaactg tagtaccaca gaagctttta ggtggggtaa taagttctat
    35161 gttagatgca catccttatg aagaagttgc atatgatttg tacaagttag aaaataaagg
    35221 tgagatattt ggactaggta gaataagtaa acttgataaa agtatgacat tagaaagtct
    35281 ttcaaggaaa ataaaagaga aattaaatat gaaacacata agagtagttg gaaaccttag
    35341 tacagacata acgaaagtag ccgttgtaac aggagctggt tcagaatttg taaaaaaagc
    35401 taagagacaa ggtgcagaag tactaattac gggtgatgta aagtatcatg aggcacaaga
    35461 tgcacttgat attggaatgt gtatagtgga ttgtggtcat tttgatacag aagatatatt
    35521 caaaaatgtt atgaagagat ttttagatga atttagtgaa attgaagtaa taaaaagtaa
    35581 tgtatatttg aatccattta gtactattta gcagtgtttg ataataaaaa tactatataa
    35641 aaaataaatt tgagtttaat tagggggata atgatgaaag tagcagtaat ttttcatagt
    35701 gtttgtggga gtacatattt attagctaga gaatataaag aagcgcttga agaaatgaat
    35761 atcgaggtag atatatttag agtaagtgac gaagttgcaa aaacacttcc tcaatattat
    35821 ttgataaatt ccaaagaata caaagacgaa tttgaaagta taaatgtaat taaatctgga
    35881 aaagaaatat tagattatga tgctatattt atgggttcac caacatatta tggaaatgta
    35941 tctggaccaa tgaagatgtt tatggatagt ttttctgata tttgggtagg tactcctttg
    36001 agtggtaaaa tatttggttg ttttgctaca gcaggttcac aacatggagg aggagaatta
    36061 gctttgcaag ctatgaatat atttgcccaa catatgggaa tgactctttt gtcagttcca
    36121 tgttcagtaa gaggaggtta tccagcgtat ggaatacttc atatagcagg agataattct
    36181 gatataagac caaatgatga tgccaagata ggtataagag attacctaaa aagacttaac
    36241 atataagaat atcatataaa aatacctaaa agcgactgta tatactttta ggtattttta
    36301 cttaattata aacgtgaagc tttaccagaa atatggtcaa tttctatttt aacaacagtt
    36361 gttaagttca tatccttctc tatgtacttc atgccttctt caaagaatcc tttagaatat
    36421 ttttttatta tttctacaag agcatttttc ttttcttcat tttctacagt gcaagctttt
    36481 ccaaaaacta tagcactaga ataagtagta ctaaatttat ctggaataac actttcatta
    36541 gcaactacta aaaaagaaac tttgttgttt ttcgatatat tatctaactt atgcccattt
    36601 cttgcacaat gaaagtaaat agaatcatta aagtatacat aatttacagc aactccataa
    36661 ggataaccat tttcagatat agtggaaaaa gtaccaaatt caccattttt taatacttca
    36721 acagtatctt cttttgtcat ttctcttttt ttcaatctca tttctttaaa cataatatca
    36781 tcctttctaa ttttgatgct taaattaaat tttagaacat ttataaagat tatgctatgt
    36841 tttttacaaa ttttaagaaa aaaatatagt ttaagataaa aggtagtgaa agagaagcta
    36901 tttggaggtt tatttatgat attattgtta gagtagtata aacaatacta ataaatttaa
    36961 tagctggttt cttgttattt aagatagtaa gcatgtctat aagaagggga agttatcgag
    37021 ggtagaagtt gttatttata actatattat aaagaaaata ttattatata aaataataaa
    37081 tagtaaagag gtatcaagtt gaatataata cttaatacct cttcaaaatt aagttataaa
    37141 agtgttgtgg gaattgtcct atacatggta aggagataat aaagaatgta tctttaaagt
    37201 ctcaactaaa cagcaaaatt tatccaacaa acatacaata aatgcttctt tgtatctagg
    37261 tggcttaaca gtaagtggcc acatgtgttt taaaattatg tccgtttctt tttcatttat
    37321 ttgaaaaaat aaagttgcat tttttaatgc ttctctaggg tgagtaaatc catgtaatcc
    37381 ttttctatca cctttgtaat gccaatcata aagaaaaaag tcgtgtagta aagctcctct
    37441 aataacactt tgaatatcaa cacttaagtg caatttttta cataatagat aactataata
    37501 tgctactgac aaactatgtt caagacatga aacattgcca tgatgaggaa atgttctcat
    37561 aagttgaact ttttcagaag aaagtatctc agaagcacat tcattaaaat atttgatttc
    37621 agcttttgac aacattatga aaatctccat tcttagtaat atataaatac tatacttcaa
    37681 cgataatatg aaatatttct tatcctacaa aatataatac ccaataatac aagtaagata
    37741 ccttttatgg tattttaaag taagagagat tttattaggc taaacaatga aaaaattaaa
    37801 agtaaagcta tagcaatata tagtattttt ccaagaggat tgccaaaatt tatagtccat
    37861 ccaataccaa accttttatt aaccattaat gatgggtcat ttggattatt atacatgatg
    37921 cctgctatcc aatacttctc atcttcttct ggagaataag atgagttgaa ttttaaattt
    37981 ggggaattaa tatatgttgc tattaaataa attataacta aaagcgttgt aatattcata
    38041 gcagttgata gttttgtttt tattgataaa agagtagtaa aaaactgtgt tgtcattata
    38101 atcatcaata ttaaaaacaa ataaccaatt ttatttaaat atttaatgtt ttcaactcta
    38161 ctttcttcaa ttctatttgt atctatctta atccttgact ttatggatcc aatggaagtt
    38221 atatataata aaaccattaa acaaaagtca gtaccgatta atttaaatac attaagaaat
    38281 gatttatcta taaaaacatc aggagaccca tttatgttcc aatgagtggc aattgagtct
    38341 ggcaattgat tataattaaa tgctataaaa atactcattc ccaaagtaaa tagtatcggt
    38401 attaaataga ttattttaaa tttttttatt attttatttt tcttatttat aaaatccata
    38461 tctactatta attttgaatc tatatctata tgacctaatt tagaataaat ttctgattta
    38521 agcttcttag cttttttatg tgtatgaata tatagtatac tttcatataa taaaaaacct
    38581 ataataccaa taaaatagga aagttccaat ttattaaatg taaagaccag aataaaaact
    38641 aatataaagt ctataataaa acctaaagat aatagttttt taaattcttt atctaacttt
    38701 ataaagtaat tataattttt atgctcttgg tctatagaaa ctccatagat gtgtttttta
    38761 cctacaaaat agggcataaa ataaaatgta gcatacatca aaattagaac tggaaatatt
    38821 gtaaatagac attcaatctt actcataata tttcacctca tacttgtcaa ataaacttga
    38881 acttagtgac aaaaattctt ctttactaat acctgataaa taagattttg ccaccaataa
    38941 ttccaagtca agtttatttt tttgacgagt tgtattatct attttcattg gtagttgagc
    39001 tacaatagca ccttttcttc tatcaatatt taagaatccc tcttctttta attcattgta
    39061 ggatttgttc actgtatgta aatttacacc aatattttca gccatacttc ttacagatgg
    39121 aagtgattca tttattttca attctcctga agctatagcc ttagttattt cttctttaat
    39181 ttgtacataa atagatttat cactattaaa atctaaattt aaaaccataa aaaacctcca
    39241 ttatgcttta taaatgaaaa cgattgttat atacatagta taacataaaa aataataaca
    39301 aacacaaaat ataagtttat attttgtaaa aattgtaatt taaaaaataa cataattttt
    39361 attaaaataa tacagatact atttatagat agaaataaaa attagaaagg agaaaaaata
    39421 tgttaacata tttaatgaaa agacaaatgc ataaaaaaga tgatggaatg agtaaaccaa
    39481 tgatgattac aggagctgta attacaggtg taggagcata tgctgtatat aaaatggtaa
    39541 aaagccataa atctaattct caaatggtca atacaaatta ttatggaaat agcgattatg
    39601 atgattataa atatgacgaa tttgattatg actgtgattg tagagacaca aaacaagatt
    39661 atgaatatga agaattaaaa aaaaaagtaa aagaatttaa ttcaagaaga ataaattgtg
    39721 aaaattgtcc acatgtttct caagaagaaa tgatgcaata tgtaaatagt gttaaagatg
    39781 taaaggaaga gattgattta catgaagatg ctaaaaaaga taatatttac aaagaagatg
    39841 aatacaaaaa atatgaagaa gaataagtaa tattttgtat aactgaacaa atagtaatgt
    39901 caaattattt aatatctagt tttaatatgt aagttgtaac ttaacttgaa agaatcagta
    39961 tcattcttta gatagttaag taacaactta cattttattt ttataaattt taatagttct
    40021 ttgtgactat tttgtaattt tagaaatatt ttagtatcca gggtaattgt gtataataaa
    40081 acttgtatag atagatagta tgaaattaag cagatagttt aaaattaaaa tgaaaagaaa
    40141 ggaaatagtt atgttaaagt tgttgatagt tgaagatgat agtactatat cttttggaat
    40201 aaagtatgct ttagaacaag aaggatttag tatagatata tcaaaggatt tatctagtgg
    40261 aaaagaaatg atttcttcta atgaatatag catgatactg ttggatgtta cattgccaga
    40321 tggaactggt tatgagcttt gtcaatatat aagaggattc tctcaggttc ctataatatt
    40381 cttgactgct tgtgatgaag aagtaaatat tgtaatgggt ctcgatatag gtggagatga
    40441 ttatataaca aaacctttta gaattagaga attaatatcc agaataaaag ctgttttaag
    40501 aagaaaaggt aatacttcag aagaaaataa gaaaatactt aaatttggag atttaagtat
    40561 atatacatta gaagctagag tatataaaaa tgataaagaa atatttctga catcagttga
    40621 atataaactt cttttaattc ttatacagaa taaaaatact gttttaagta gaactcaaat
    40681 attggaaaaa ctttgggatg taacttatga ttttgtaaac gacaatactc taactgttta
    40741 tataaaaagg cttagagaaa aaataggtga tgatttatgt gaaccaatct acatagaaac
    40801 tgtaaggggg attggttata aatggatagg aagtgaaaat agtgtttcta tataatccag
    40861 aagtgaagaa gtttttaagt aagtatgtta ctttgatgtt tattgttatc ataatatcta
    40921 ttggatttag cataatcaac gtgtccttaa ctaaagagat ggttgtaaga aataatcagg
    40981 ctataatagg aactttatca agcaagtatc caaacttgga aagtcagata gtagacataa
    41041 taactcaagg gaagtctatg gagaacatag attatggtca gaaaatatta attaagtata
    41101 attatgataa atctattagg ataaactctg agcctattat ttctaaatta gttttagaga
    41161 ctatcaaaat aaatataata ttagtatgta taatatttat tttgatattt gtgttggttg
    41221 ttagatattt taagtcaatt tacaatgatt tatcagatat gactaagtat gtttactata
    41281 gttcagaggg taagccattt gatatgaaaa acaagaatca agaagggcag ataggtcttc
    41341 taaaaactga actcttaaag atgacaacaa ttcttaatga aaaggttgaa cttttaaaaa
    41401 gagaaaagat atttttaaac aatacaattt ccgatatatc acatcaatta aaaactccta
    41461 tgacttcttt aataatgttg aatgatttat tatataatga tgtaccatac gaagtaaaaa
    41521 tcgatttttt aaataagata aaaaatcaat taaatagaat ggattggttg attaaaagca
    41581 tgcttaaatt atcaaaggta gaagcaaaag tgataaattt taaaaaagat aaggtaaaat
    41641 ttagtgaact catacataga gcaatgctat ctatgaaaat acctatggag attaaaaatc
    41701 aaaaactgac tatagaggga aatgataatg tatcttatat tggtgatatt gattggtccg
    41761 tggaagcatt agtgaatata atcaaaaatt gtgtagaaca tactcctgaa tttggaaata
    41821 taattataac ctataaagaa aatccattat tttctgaact aataataaaa gatgagggtg
    41881 aaggtataga taaaaaagat ataccacatg tatttaaacg attctataga ggaagaagta
    41941 gttcaaaaga agatagtgta ggaataggtc ttgcaatgtc aaaatctata atagaaagcc
    42001 aaaatggcga tatatatgta aacagcgaaa aaggtcaggg tacagaattt catataatat
    42061 ttcataaaat gtatgatagt gactaatctg taatatttaa ttcactttat agtaatagcc
    42121 aaaacctaat atatgaagta tagaatataa atattggagg tagttatgga aattttaaga
    42181 gtagaaaatc taactaaaag ttatggtaaa aatgaaacaa aagttgatgc tataaaaaat
    42241 gtaagtttat cagttgaaaa aggaacgttt atagcaataa caggtccaag tggaagtggt
    42301 aaaagtacct tattacattt attaggagga gttgacagac caactagtgg taaggtttat
    42361 ataaatgatg ttgatatata taatttaaaa actaaggatt tggcgatatt tagaagaaga
    42421 aatataggtc ttatatatca attttacaac ttaattccag tcttaaatgt gaaggaaaac
    42481 atattgcttc cagcagagct tgacaataga gatattgata gagaatattt tgatgattta
    42541 atgaaaacat taggtctaat tgatagagaa aagcaccttc caaaccaatt atcaggaggt
    42601 caacaacaga gaacctctat aggacgtgca ttaattaata gaccttctat aatattagca
    42661 gatgagccaa caggtaattt agatagtaaa aattcaaagg aaatattaga attgttaaaa
    42721 ttgtcagtaa aaaaatacaa ccagacacta ataatgataa ctcatgacaa aaatatggca
    42781 cttcaagctg atagaattat aagcatagaa gatggaatca taaaaagtga tgaggtgatg
    42841 tagatgaatt tatatacatt actaaccatt agatacttaa aacaaaataa aagaagaacc
    42901 attgtaacca taatcggtat aatactttca acagctttaa tttgtggtat aggaaatata
    42961 tttgaaagtt ttatggatta tcaaatgaga gaaactataa agaatgatgg aagtttccat
    43021 gttacatttt atgatgtaaa tagaaaaaat gtggaatatg taacgaaatc agctgaaata
    43081 gaaaaacatg catttaccaa acaacttgga tattctaaat tagaaaatag tgaaaatgct
    43141 atattaagta taaagcaata tgataaaaat gcaataaatg gatataaagt ttctataaaa
    43201 gaaggtagat ttccagctaa ggaaggagaa attgttctaa gtgaaagtat tattaatctt
    43261 atagatgata agttaaaaat aggagataag ataactttaa aagtagggga tatgtttgac
    43321 tcaagcaaga aaaagattga tagtatgaca tttcatgaag gtgattatat agcaaatgaa
    43381 aaagatagaa cttttaaagt tgttggtata attgaaaaac ctgggtttga acgttataat
    43441 ggaattgcaa cagctatagc ctactttaat cctatgaata attacaatga tacaattaat
    43501 gtatcagtag cagtaagaaa tcctaaagat gtgtataaga taagtaataa aataagtaaa
    43561 aatatatatt caaataaaga taaagaagca gtttctgata tgataaaata caatgaacat
    43621 ttattgaggt tacaaggtgc tagtaagtat tcaaatataa ataactctat aaagtctata
    43681 attatagcag taactatttt agtaatcata tgtacaattg ctacagtgta caattccttt
    43741 agtatttcta taaatgaacg aaaaaaacag tttgggatat taaattctat aggtgctaca
    43801 tctagtcaaa ttaaaagatt agtttttata gaaggtatta taattagttt aattggtata
    43861 ccaataggac taatatctgg aacagtagct atagacctat tgtttaaaat tataaataag
    43921 tattttactg aatcggttgt tactaagatg agtttgcaga tagtgtataa tccaataata
    43981 actattgtta gtataataat agttttgctt acaatcttta tatcaattct actacctgca
    44041 atatcggctt ctaatatttc tcaccttaat gtgattaaaa atactggaga gtataaagtg
    44101 ggcaaaatca aaagctcaag acttattaaa atgattttta aaactgaagg agtacttgca
    44161 tataaaaata ttaggagaaa tagaaaaaaa tttataataa ctcttttttc tttaatggta
    44221 agtataataa tatttatatc ttttagtggc tttacattac ttttactaag aggtgaagaa
    44281 attagaaatt ctcaaagaaa atatgatttg tatttaactg caaagaacac agctaggtct
    44341 gtagaggata ctataagtga actagaagat attgatggga taaaaaactt tgaattggca
    44401 acaggacaat atgtgtctat aagagtaagt gaaaataaaa taaataaatc caaggaagat
    44461 ttaatcagga aatattatca aaaatataag attggagata gttatgaata tgatttcagt
    44521 aataatgaat taatttttcc aggagatttt gcagtaaaaa acaaaataaa taacttagta
    44581 cagggctctt ttaataaaga gagagcaatt gaagaaaatg gtgttatatt agttagaaaa
    44641 agtgcatttg aagaaaatgg gaagaaaggt gtagtagaac ttaccaacta taaagtagga
    44701 gatacagtaa attgtgaata tcttgatgaa aatgccttaa gtaaaaaagt aaaggtcaag
    44761 attcttgcta taactgacga agaacgtcta ggtcttggtt atcaaaatat ggggttacaa
    44821 tttataactt atgatgaagt tgctaaaaat ttaaatttaa aattaagtaa aagccttata
    44881 tttattgatt caggaggaag cattaagact aagaaggaaa tagaagcttt ggcaaataaa
    44941 aataatttta acttttatga tgaaagtgca agcaatgaaa gtgaaaaaca agatttaaag
    45001 gttattaaaa tatttgtata tggttttata gtagtgatat ctttagtgag tgttacaaat
    45061 attctaaata cagtaagtac aagtataaat ctaagaaaaa gagaacttgc agtaatacaa
    45121 tctatagggg ttactcctaa aggatttagg aaaatgatat atttagaaag ttttatatat
    45181 ggtatactgt cattgttgtt tggaatacca attagtattg gtataattct aattatgaat
    45241 aaacttattt caggtgtaat tgaattttct ccgattatac cgtggacagc catagttatc
    45301 tgtatagtaa gtgtttttat aataactttt atagcagggt atataccaat gagtaaatta
    45361 aataaagaaa atataataga taatataaga agagaaagta tatagatata aaaataattc
    45421 ttaactatat aaaatattat tatatcactt aaatgatttt ttatttatat aagaaatcta
    45481 ataataaatt actagaggta tttaactatt tagaaagaat tggtattata taaagtaaga
    45541 gaatatataa taagaaagaa tatttgattt tattggaaaa caaaagaaaa agaaggtgat
    45601 tactatttct catataactg cgaagaatat gtataaaagt ttagaggaaa gaataaacaa
    45661 gtttccacaa ggtgctccac catctgatac attatacaaa atactaaatg tactatatac
    45721 agaacaagaa gcgaagttag ttgctcagct tccaataaag cctttcagag taaaaacagc
    45781 agctaaaatt tggagtgtaa gtgaaagtga agcatataga gtattggata aacttgctag
    45841 taaggctctg atactagata tagaagataa taaagggaag aaatatataa tgcctcctcc
    45901 aatggctggt ttttttgagt ttgccatgat gagaacgaga cacgatatag accaaaaact
    45961 tttggcagag ctttactatc aatatatgaa tgtagaagaa gattttatca aagatttatt
    46021 ttattcaaca gaaacgaagc ttggaagagt atacgttcaa gaggaagttt taactaatga
    46081 taatgaggtt agtattttag attatgaaag ggctactcat ataattgatg aatcaactca
    46141 tataggtata agtatgtgtt actgtagaca tagaatgcaa catgttggaa aagcttgtga
    46201 tgctcctatg gatatatgta tgacgtttga caatgtagca aattctttaa taaataataa
    46261 atttgcaaga cgtgtggata aaatagaatg taaagaacta cttcatcaag catatgaaca
    46321 taacttagtt caatgtggag aaaatgttag gaaaggggtt acgtttatat gtaattgctg
    46381 tggatgttgc tgtgaagcaa tggtagcagc taaaagattt ggaaatcttc atccagtaca
    46441 gacaacaagt tttataccaa atataaacca tgaaaattgt gtaaagtgtg gtaaatgtat
    46501 aactgcatgt ccaatagatg cgataagcaa ggttaaggaa gatggtaaag aatatataaa
    46561 aattgatgag gatagatgtc taggttgtgg agtttgtgtt agaaattgcc ataaaaatag
    46621 cattatgtta ttaaagagag atgaaaaaat aataactcca gcaaattcag tacatagagc
    46681 agttcttatg gcaattgaaa aagggcagtt acaaaattta atttttgata ataatgctct
    46741 ggctagtcat agagctatgg gagctatact gtcagctata ttaaagcttg aaccagctaa
    46801 aaagatttta gccagtaaac aattaaagtc agtatattta gataaattgt taagtatgaa
    46861 tgataaatag aaactaactt aaaaaaggca aagttttaga cttatctata tcttaataaa
    46921 cttatcattt aatatttaaa tttaattttt acacatataa aacttataac ttaaataaaa
    46981 aaaggctata ttcaattaat attacttgaa tacagccttt tttagttatg ttaagctatt
    47041 tcttttattt gcttaaatga gttttcattt ccatttccac caatttgtgt tacagattta
    47101 aatctcatag ttttaaatag ttctttttga ttataatcta gtgagtttcc tactagcatt
    47161 acaggagatt tagtttttcc agccaaaact ccaacagata atccgtctat taaatcatct
    47221 tgtttattca ttccattttt agcaacatat aaattgtcta tcttagaatc cttgtaaaat
    47281 tcttttatta cttttgcatt agtttcattt ctagtgctac ctgatattct ctgtggattt
    47341 tgaagtttac tttctatatt tttagaaact gtatattctc caccgattac ataagattta
    47401 tcaatctttt tgtttttaaa caagttattt atttcagtta tattactatt ttcattagta
    47461 agtattatag gcatatcatt ttgagctgat acagctccaa tgcttactgc atcggctaat
    47521 cctttttcgc cattaactac tgaaatcttt gatatattgc taatattgtt caattcttta
    47581 gcaatgttca tagaagtttg atatctatca cttcctgaaa ttctagatac agagatattg
    47641 tttgatttta tagtatctaa agatttttca tttatagaag cttctccacc aactacatat
    47701 acatttttaa cttttaatct ctttaattca gccaaagttt tttcatttat ttgagagctt
    47761 ccagtcaata atataggagc gtttttcttg tatgcaaatg gtgttgcagc caaagcatct
    47821 gcaattgctg aatcgtttat taaaactgca ttttcagcat tttcccaacc tgcttgactt
    47881 atcttaatag aagtttcata tctatcagtt cctgtaagtg cacttgcatt tacttcatct
    47941 tgatatgtaa cctcaaatct agcatttgga cttcctaaga aaacaattac gcctcctttt
    48001 ggcaatctaa ctctattgtt ctttgtaact aaagaatagt ttacaggaac acctttatca
    48061 tcataaacag caaaagctga attttgagga agattaactt ctattttttt atttgcgata
    48121 tcgtcaccaa tcttatacca ttttgcataa ccattggatt ctagttcaca agtaaaagat
    48181 ttttctgctg gcaaattagt tatagaatct tcactaacat acgttagtgt tccaaaagat
    48241 aaatactctg taccattttc tttatgaagt ttaatgtcgg ataaatcacg acctattaca
    48301 ccaggtattt ctataaaagc atttgagtta ttctcatcca ttattttagt gttaactata
    48361 taacctggag tttcatcaga aagactaaaa cttgctttta cagagccaaa catatagctt
    48421 tgagaagtat atttttcatc cactagatag taacctttgc cacttctttt tttccacact
    48481 tctttgacac tatttgatat attgttgtca tctacttttt gagctacata gtataaactt
    48541 gctgtctgac ctaatccagg gacatcatca taagagctca tatttaaata tgtgatatta
    48601 tttttttctt ttacaaattt taaacaacta ttaccttttt cagatacaaa tctatcttga
    48661 cctatgtata cgtatttatc ttcaggtcca ttttctatat aaggagaaga tactgttaaa
    48721 gtaccattat cattaacatc tacttttatc atatttgaag aagcataaag accactattt
    48781 tcttttaaag agctaggcat tttaacttgt tgtggcttac taaatgtttt atcaggtttt
    48841 atttctttaa ttttaccttt ttcttttaat gcagatagta agatttcttg tccaattatt
    48901 tcattaagtt gactacttcc accagaagaa agaactgcaa ctgccatatt ttcatctgga
    48961 agaactataa gattactgtg gaataataaa gaatctccac cttttgtaag agcttttaaa
    49021 ttatactgat taaatggata agtgttgaca caatcccacc ctaaaccata tccaagtata
    49081 gagtcttctc cttcaggcca tagaccattt aaatattctt tgttttccat agcttttact
    49141 gaagcaggag aaagaatacc atttgaattt ttcataaatg tttgtgcaaa tgtacataga
    49201 ttttctgcac ttgaatataa accacctgca cctatagcat taaggttatc ttgtggaact
    49261 gcatcttccc aataaggtac atatgctttt gctagttttg aactatcaaa actattttct
    49321 ggagtttttg tattttgtaa gttaagtgga ttatttatgt atttatcaag aaaattagta
    49381 aatgacatac cagatactct ttctactaaa atttcagcta aagtaaatcc atcattacaa
    49441 taaacagaaa aagctcctgg tttagctttt aatctttgtt tttgtaattc ttttaagaaa
    49501 ttatcatgac cataagaatc attgtctgct aataaaatag tgtttttaaa actacttccc
    49561 atcaaccctg atgagtgatt taataacatt cttggagtga tttccttgta tctatcatca
    49621 gccattttaa attcaggtat atactttaca acaggagtat ctaaatttaa ttttccatca
    49681 tcaaccaact tcataacagc tgttgtagta aacattttac tgatagatgc gatactatac
    49741 atattatcct tatttaagtt tttgttatcc tgtttgctgt aaactccacc attaccagaa
    49801 atctcaattt tgccattatc aatcaaagca tattgagcac ttacagcacc atactttgat
    49861 agcaaagttt ggattttctc tttagcaaga gctttagttt ttgtgtaaga ttccgcgttt
    49921 ttactataat catgtaattc tatatcagaa ctttgatatt tttcggaatt atcttttgta
    49981 ttatcagcaa aagtaatatt tggagcagca gtaaataaca tactcaatac taatgtacta
    50041 gataataatt tagagagcct ttgcttaaac atattacatt acctctttcc ctttttaata
    50101 atttataatt agcataacat tcttaattat tttaatcaac agattattat caataaaaaa
    50161 agcttttata agtatagctt tttatataac agagaaaaat ataaaaataa tatttgttgt
    50221 tgtataaaga ataaagggta taggtaatat ataaataaaa tggaggaatt ttagacatat
    50281 gtataagaat ataaataaga agcaacttaa agaaatgatg aaaaatgaaa aggatgtttt
    50341 attattagat gtaagaacta aagatgaatt taaggaatat aaaatagaaa atgctataaa
    50401 tatatcttta caagagttaa tcaataatat agatgaaatt tacgattata aagataagaa
    50461 agtagtagtt tattgcagaa gtggtcatag aagtgttact gcatgtaatt tgttagctga
    50521 agaaggtttt gagcatttat ataatttaaa ttcaggaata attgattata tgagttaaat
    50581 aatgtaagtt atacattaaa tactatgtat agctctgctt attaagtagg aatatatcta
    50641 aatatttata agataaattt aggaaagaac gaattttttc gtttttttct atgacagttt
    50701 ttgtagtaaa tattagtttt taagttggaa aaaggtagta gctttttagc tactaccttt
    50761 taatatgaac ttagaatatt attaaaaaaa tatatttaaa gacagaatta attttttaat
    50821 gaccagttaa attactatcg ccgaatttat cattaaatgg ttttataact ctatttatag
    50881 gtccttttag aagtacattt aaacaaatag acagaatcat aaatagtaat agaactagta
    50941 tatctttagt tagatttgga gcatatatac caccaactgc ttcccttgta gcacctattg
    51001 cataggtaaa tggcattata gggtttattc tttggaagaa tgtaggtgta acttgtatag
    51061 ggaatgtacc accagaagaa ccaatctgaa cgactaatag tactattgca attgcttttc
    51121 ctacatttcc aaatacagaa actaaagaat acactataaa gttaaatacc atactagtaa
    51181 acataagcag aactatcaat aaaattggat gttttgctgt tactcctaac aataatatat
    51241 ctccagttcc tattataaaa ccttggacaa gagctatact taaaaaagta aggcctcttc
    51301 caaagtaaat ttcataaggt ttatagtttc catgtacaga tgtagacaat agtgctgaaa
    51361 taagtaatat accaacccat gtagaaagaa cactataaaa tggtgtcatt gcagaaccat
    51421 aattttcaat tggatataat ttctctgttt tcacctcaac aggttctttt aagaaattag
    51481 actttgtcaa tatatcactt tcaagcaagc tgactaattt tttcatatct tcaccattac
    51541 taattttgct taaagtatca atcaaatcat ccaacattcc ttttgctaaa ggaagtcttt
    51601 ctcttatcaa tgatatactt tcctgtgcat ttcctgaaag ttttagagaa gtagtaagta
    51661 tttcttcaac ctttggaagt tttgcttctg ccttatctaa aacagtaatt atatcatttg
    51721 ctacttttat actgtttgca aatatactat ttataggttt tgatattttt gagtcaaaat
    51781 tatttaaaat atttaaatta attcttccaa taccatttga tagacttaaa acattattca
    51841 aagcacttat agatggttgt tgtccagata taactttgtt tttaatatca tttaatgttg
    51901 atatagatga atctatttta ttgctagagt cttcaagatt atctatgaca tcatccaatc
    51961 tattatttga tgtaagttgg tttaatttag ttaaaaaatc caccaaagta tcatttaaag
    52021 attgcaaatt agaaagtttt tctgataaat tatctatcaa cttaggtaca tcttcactgc
    52081 cactatttac tgcatcaatt aaatttaatg taagagaaga agcagaagat gaaaggtcaa
    52141 ccattaaatt taagtcagac ttaataagag gagaaagttc gtctaaatta tcatttgtat
    52201 cctctaagaa tttttttaag tcacttgata atagttttgt atcattcaga gtctttttaa
    52261 ttgtaggtaa atcagattta atatctttaa ctgtatcaga taattttgaa gtagcatcag
    52321 aagctaaatc aacagtctta tttatatggt caaatctctt ttgaaggtca ataagggaat
    52381 tttcaacttt tgtcaatttt ggaagactgt gttcaattcc tgcaccaact ccgtttgata
    52441 taccaagaac gatttcacta actgttttta ctatagtctg attaacctgt agttgtattg
    52501 tagaagcacc tttatctgta atctttggtg caactgcatt tattttttca ttaacagtat
    52561 agataatttc gcctttttta acatcatctg taattaaaga tgtcaaatct tttgtaaaat
    52621 tttttggaat cttaagtgat gcataataag tacctttttt aacaccttca agagcagttt
    52681 tttcatctac aaactgccaa cctaaactct tgttatcttt gagttgttca attaattggt
    52741 ctcctacatt aatcttttgt cctgctattt catttccttt atcttcattt gttactgcta
    52801 caagcatatt agcagtgctt ccataagggt cccaagatgc ctttatattg aaccaagcat
    52861 acagagatgg taaaaaagca agacctaaaa ctattacaag tacggcataa ttgccacgta
    52921 tatcttttag gtcactttta aaaatttcta atatattttt taaacccttt gaaggtctta
    52981 aattcttgat attattccag tttaaaattt cttttaaact attagttttt ttcaaatgtc
    53041 tcacctccta aaatattttg ataaagaaaa aagttagatt tataatcaat tttaaattat
    53101 attacttttt acacaaatag taaagttaaa attttgtctt aattttaata catatatatt
    53161 atatataata gtatgctata aatatatata aatataggaa ataaaaacaa ataatttata
    53221 aaatatatgg tataaaaatt aataataaat caaatattta taattgatat aatcaattaa
    53281 attagccatt atgatatact tttggtaatg agaaaattct atgaagggat gattgaatga
    53341 ggtattttaa aaaatacata aaaaaatata tagtattatt tctaacagca gtattttttt
    53401 taacattgga agctttttgt gatttagctc aaccaactat aatggcaaaa ataatagata
    53461 taggggtttc aaataagaac ttagactaca tactatcaac aggagctata atgataggta
    53521 taactttttt aggtgcaata tttgcaataa taagaagtgt aatctcggca agagtttctc
    53581 agcatttttc ttatgattta agacaggatg tatttgaaaa gataaataca tactcattaa
    53641 aacaaataga taaatttggt agagcttcat taataacaag aattactaat gatatcaatc
    53701 aaatgcaaca attcgttaat ggaatgatga gagtttttat aaagtcacca ataatgtgta
    53761 taggaagttt aattatagct ataaaattaa atttaaagat gtcaataatt attctaattg
    53821 cagttttaat tatatttatt ataatattgc ttaatatgaa gatagggtat agattattta
    53881 aaaatgtaca agaaagtaca gataaagtaa attcaaaatt aagacagttt ttaagtggaa
    53941 taaaagtagt taaactattt tgtagatacg attatgagaa ccaaagcttt gaagagttaa
    54001 atgatgaact ttttaaaaat agtagaaaag ctacaactat gatgtcattt tttagaccga
    54061 caattacaat aatcattaat gtttccataa taataatatt actgattgga aggcatttaa
    54121 tttattcagg agaaattaaa attgggatta tagttgctta tgtaaactat atgactagaa
    54181 tattaacatc tcttataatg atttcacatg tttttaatgt ttttgttagg gcaaaagcat
    54241 cttatgagag aataagtgag gttttggttg atgagaatga agaagtaatt gagagagaag
    54301 aaagtttaga tgttggagaa aaagatttaa agtttgtaaa ctgtgatata atttttgaaa
    54361 atgtagattt ttcgtataac aaaaatacag atgaaaaaat attaaaaaac gtatccttta
    54421 aaatagaaga aggtcaaaat attggtgtga ttggtcaaac tggttcagga aagacttctt
    54481 tagtaaattt aattcaaaaa ttatatataa ttgataaagg tgatattaag attggaggac
    54541 gtagtatata cagtatttct gaagaaagtt taagggcaag aataggtgta gtatttcaaa
    54601 atagtagtgt gtttggaaaa agtatattgg agaatgtagt tatgggaaat agagatatat
    54661 gcaaagagga tgttgtaaaa tcatgtgaaa tagcaaatgc aaatcaattt ataacaaaac
    54721 tcgaaaatac ttatgatgaa gttttattcc aaaggggtaa aaatttatca ggaggacaga
    54781 gacaaagaat tactatagct agagctatag ccaaaaaacc acaaatatta attcttgatg
    54841 attgttttag tgcaatggat attaatacag agacaattat aagaaagaat ataaaagagt
    54901 atataagtaa tttaagagaa aaggaaagta agaaatgtac tgtaataact atttcacaaa
    54961 agattagttc tataattgac tgtgataaga ttttagtctt ggatgagggt gaggtggttg
    55021 gatttgctac acatgaagat ttactggtta gttctccaat ttataaaaaa atttttgcgt
    55081 tgcaaaattt agtaagtgaa gatgtaaatt aaggaggaag tatattgaat ttaagtactg
    55141 gaaatcagaa ggtcagtaga ttaaagaaaa aagaaaagcc taaagatttt aaaaaaacgt
    55201 ttaaaagaat ttttatgtac tttaaaaaag ataagaagat tactagattt atttttttgc
    55261 tagtaataat tgattcaatt atatcaactg taataccata tactattgga aaggtagttg
    55321 acataataga tatcgatact tattcaaaat ccattttctt aaaaggaata attattttac
    55381 tttcatttta tataattgag ttttcagtta aactgtctaa gggaatatgt acagctagat
    55441 tatctcaaag tatagtcaga gaaatgagaa gtaatttatt tttaaaattt aaaaatctac
    55501 caataacctt ttttgataaa agttctactg gagatattat gagtagagtg acaaatgatg
    55561 tcgataatat cagtacagga atatcaaatt cattagtaca gttaattaca ggaatcttaa
    55621 acatattgat gacttttatt atgatgtttg tattaagccc aattttaacc ttttgcagtg
    55681 taatattaat accgatagta atgtttgtga gtaattttat tgcaaagaga actagagttt
    55741 tttttaagca acaacaagtt gagttgggaa aactaaatgc acatattgaa gaaatgatat
    55801 caaacataaa tgtagtaaaa tcttttaatt atgaaagaaa atctgtaaat gattttaaag
    55861 aagtcaatga tagacttcta aatatttccc ttaaatcgca aatttacact tctcttttaa
    55921 tgcctattat gaatgtgatt agtaatatag gatttgcaac tatatgtatt ataggaggca
    55981 ttcttgcatc taaagatatt ataaccatag gggttatagc tagtttttta agttatgtaa
    56041 gacaattcac aagaccttta aatgaattag caaatctatt taatacatta ctttcagcca
    56101 tagctggatg tgaaagagtt tttgaaatta tagatgaaca agaagagcaa gaagtgcata
    56161 acatgtttaa aagtgagatt aacgataata aagatggtaa tttaaactct cattttgtaa
    56221 agggagaaat tgagcttaaa gatgtaagtt tttcttatga ttcaaaaaag aaaattttag
    56281 ataatataaa cctaaaaatc aaatctggca catcaaatgc catcatagga gagacgggaa
    56341 gtggaaaaac aactattata aatctaatta caaattttta tcatatagat gaaggaagta
    56401 tatttttaga tggtaaggat atatactcta ttaacagaaa ctatttgaga acttgttttg
    56461 gagtagttcc acaagaaggt tatatattca atgatacagt tatggaaaat ataaggtatg
    56521 gaaatctgga ggctactgat gaagaagtta tatatgctag taaaatagca aatgcacata
    56581 aatttatagt taaaatgcgt gaaggatata gtactgtatt atcggatagg ggtgaagatt
    56641 taagtgaagg tcaaaaacaa ttaataagta ttgctagagc agtattaaaa aatgctccaa
    56701 tacttatttt ggatgaggct acaagtaaca tagatatagc aacagaagct aaaattcaag
    56761 aagcaataaa taatttaact tatggaaaga caagtataat tatagctcat agattaagta
    56821 ccatatcaaa ttgtgataat ataatagttt tagaaaatgg tagaattgtg gaatcaggaa
    56881 atcataaaga attgataaaa ttaaagggac attattatag aaacatatta ttgacacagg
    56941 gaaaataagt atttagaaaa aacttttaaa aaaattgttt aaaggtatat ggtgcgggta
    57001 tatatagact aacttaataa ataaaaaatt taatttgata tataaaattt aggaggaaag
    57061 taattatgaa gaaatttgtt tgtacagtat gtggatatat acatgaagga gatgctgcac
    57121 cagcacaatg tccagtatgt aaagttggag ctgataaatt tgaagaaatg aaaggcgaaa
    57181 aaaattgggc tgatgagcac agaataggag tagctcaagg tgtagatgaa gaaataatcg
    57241 aaggattaag agctaacttt gttggtgagt gtacagaagt aggaatgtat ttagcaatga
    57301 gtagacaagc tgatagagaa ggttatccag aagtaggaga agcttataag agaatagctc
    57361 ttgaagaagc tgaacatgct gctaaatttg cagaacttct tggagaagtt gtagttgcag
    57421 atacaaaaga aaacttaaga gttagagttg atgctgagta tggtgcaact gatggaaaat
    57481 taaaattagc taagaaagca aaagaattag gattagatgc tatacatgat acagtacatg
    57541 aaatgtgtaa agatgaagct agacatggta aagcattctt aggattatta aatagatatt
    57601 ttggaaaata aatttaatat aaagtagatt ttaggagtat ctcacttaca atttttaaag
    57661 ttatgagtga gatatttttt aattatttgt actttatttt ttatttctaa cgattatatt
    57721 tttaataata gagaataatt taatagtaat aatgcacaac ttttaaaaat aaatgattaa
    57781 tccaaaaata aatttgattt tagaaaagta aattgacatg taaagaagaa tatattaaac
    57841 taagtataaa aaatttgctg ttttgtaaag gtggtggata atctgataaa gtatatacat
    57901 aaaagttatg tagctattgt tgttttacat gaaatctatg ggattaatag ctttatagaa
    57961 gatgtttgtc aaaagtatta taaatatgga tatgatgtat tttgtcctga acttctggga
    58021 gaaaaaagag tttttccata ttcaaaagtc caagaggcat atgatttttt tataaataat
    58081 gttggttttg atatttataa aaaagttgaa aagcttataa atgatttaaa atcagagtat
    58141 aaatatgtat ttgttgctgg gtatagtgtg ggagcaacta ttgcatggag atgcagtgaa
    58201 gattcttttt gtgatggcat aatttgttgt tatggctctc ggattcgaga ttacatggat
    58261 gtaattccaa aatgtcctac cttattagta tttgcaaagc acgattcatt tgatgttgat
    58321 tctatttctt accaactttc taggaaacaa aatatccaaa ttgagatttt agatgcaaat
    58381 catggtttta tagatagata ttcaaataat tattctgata ttcaaacaaa agtatttact
    58441 attaaagaaa aaagttttct gtctaaatat ttagcatgat ttagattatt ataaaatata
    58501 tagaaagatt taattaatct gaaaagtttt tatgacacta ttgatattta aaatattagt
    58561 agtgttatta tattttttga aataaaatta atcactagaa ttatagtgtt agttgtgctt
    58621 ttatgactta taagaaacta atattagata gtgtatttaa atagataata ataaattcat
    58681 tatagttgaa taagaatatt atatgagaat attgcaattt gatatattta ccattacaat
    58741 aaaagtagtt acaactagaa aaccaaataa gttaaagtaa gttggcaaat tggaggtttt
    58801 taaatatgaa agcatttaaa aagcacttct tgatactttc tttgatattt ttacttatta
    58861 tatcatgttt taacaatata ctatgctttg ctgatgagtc tgaaaattca aaaaaaataa
    58921 gagttggata ttgtgatgac tacggaataa tatcctcatc aaaagagcat tcttatacag
    58981 gatatggtta tgattatcta agagaaatct caaaatatac aagatgggaa tatgaatttg
    59041 taaaagggtc ttgggaagaa tgtttagaca gactagaaaa aggtgaaata gacttacttg
    59101 gacctttaca gaagaatgat gaaagaaata aactatttaa ttttcctaaa ctaaattcag
    59161 gatatgaata tagtgtacta tatacaaaag atagtaacaa taatatgttt tatgaagata
    59221 taagttcctt taagggaatg agagtagctg tacttagagg aaactttcat aatattgcat
    59281 ttgagaagta tagagaagaa aataattttt cagttgaata tatctactgt aattctattg
    59341 atgaattaat tgagtctgtc aatgaaaaaa aggcagatgc atttgtctgt ggaagtatta
    59401 taaatgctaa aggaatgaaa atagttagca aattttcagt agagcctttt tattttgcta
    59461 ctgcaaaata taaacctaat ttggtaaaag aattagatta tgctttaaaa gaattaaaaa
    59521 taaatgatat gtattatgag ttggaattat ataaaaaata tttcaaaaga gaggtcaata
    59581 attccatagc atttactcgg caagaaatga attttattaa agcaaaccca aaacttacta
    59641 tggtatatga ttcagagtgg tctcctgtag agtattatga taaggaaagc aattcgttta
    59701 aaggtataag ttccaattta atgtcaatta tatcaaaaaa atgtggtata aaatttgaat
    59761 atattaaaac aaaaaattat aatgagagtc ttgattacat aaaaagtggt aaggcaaata
    59821 tgctatgtgg ctcaatcaat gaaaatgata aggcaaaacg atttaatatg aaattgacaa
    59881 atccatacat aaatattcca atgattatgg taggaaaact ggataccaat ctcaataatg
    59941 atttaaatat tgctttaacg agtagttata agtctatcga ttcttatata gaaaaaagtt
    60001 ttgaaaatgc taagacaaca tcttataaga gtatagaaag ttgtctaaac gctataaatg
    60061 aaggtaaagc aaacttaatg atacttagtt cttatcagtt tgatgaactt ttaagagaag
    60121 gaaagagtga gaatttatct gttatatctg ttttagatac aagctatggg atgcgtatag
    60181 gggtatcaaa taaaactgac cctatattag tatctatttt aaataaatca atagacaaaa
    60241 ttactgaaga agaattaagt gattgtatat attctaatac tattgacaaa ccttataaag
    60301 taccatttgg tgtgattttt aaagaatatt caatacaaat tatttctttt gtatgtattt
    60361 tattcttaat tgctattaaa tatataattt ataataaaaa gaagaaagag gattatctaa
    60421 agaagatagc atatacagac ccattgacag gagcagatag tatagataaa tttaaaataa
    60481 attcgaataa actgtttgct aaaaataatc cagaagaata tgcattgttt tatatagatg
    60541 ttgacaaatt taaatatata aatgatatgt ttggatatga tatgggaaat gatactttga
    60601 tacatatatc aaatactatt gcaagtgaat taaaggaaga tgaaattttt gcaagagttt
    60661 ctgctgacca ttttgttctt cttattaagt ataagacaga tgatgatatt aaaacaaggt
    60721 taaacaatat ttacaataag gttcaaatac ttagtaatcc taaaataaac tattataaat
    60781 tgattttaga ttgtggtata tataaaataa gtaaaagtga taatgacata aatactatta
    60841 tggatagagc taatactgca agaaaaacta taaaaggtgg tcataaaaat tcatttgctt
    60901 tttacgataa ggaaatgcat aaaaaaatat taaaagagaa agaaattgaa aattcaatgg
    60961 tagatgctct taataatgga gaatttattg tttattttca acctaaatat agtctttcag
    61021 attatcaaat tataggggca gaggctcttg ttcgatggga taatccacaa aaaggtctaa
    61081 taccaccaat agaatttatt cctgtatttg agaggaatgg ttttattgta aatattgatt
    61141 tctatgtatt tgaggaagtg tgtaaaaaga ttagagaatg gatggatgaa ggacaaaaag
    61201 tagtacctat atctgtaaac ttgtctcgaa tgcattttgt aaatagtaat tttatagaga
    61261 agtttaaatt aattgtagat aaatacaaaa ttccgacaag acttatagaa ttagagctaa
    61321 cagaaacagc agtattagat aatatagaag ggttacttga tacaatgaac aatttgaaag
    61381 aaaagggatt tgtaatctct atggatgatt ttggtacggg atattcctct cttaatcttt
    61441 taaaagaatt gcctgttgac atattaaaac tagatagagc attttttaca gaaaaagatg
    61501 agagtaataa tgaaaaaatt gttatatcta atgtcattaa aatggcaaag gaattgaaaa
    61561 tgaaagtaat atcagaaggt gtagagacta tttcgcaagt agaatttcta aagcaaattg
    61621 ggtgtgacat ggtacaagga tatttgtttt ctaagccaat gcctgtaaaa gagtttgaaa
    61681 aaattgcttt taaaaaagaa taaagcaatg tgtaagtaat gatatatata ataaaggtgc
    61741 tttaatatta gttgagtata ctattttaga gcatctttat ttttgtatta atttttacga
    61801 ttttattaat aaaataaatc aaatgagaaa aaaaatcaaa agaatacaat aatcacttgc
    61861 aaaaaatata ctattgtgat agacttaaat caaaattagg aattgtaaaa agaaggaaaa
    61921 aataggatat tattttaata gattaagatt taaggtattg taatttatat ataagataac
    61981 gattgcttgt agatttaaat tagtttaaga ggagggatat tatatgatgc cattgatact
    62041 atcaaataca ggtgaagaag tagttataaa gaaaatttca ggaagtgata agacgaggac
    62101 ttttttaaat agtataggtt ttgtagtagg tacaaatgtt aaaatagttt ctaagataga
    62161 tggtaactta ataatagacg taaaagatac tagagttgca ttagataaaa aaatggcaag
    62221 tagaataata atatagggag gtaatgacat gaacagactg aaggatatta agtgtggaga
    62281 gactgtaaaa gtcaaaaagt tagaaggaga aggagctaca cgaagacgta taatggatat
    62341 ggggattaca agaggcgtta atatatttat aagaaaagta gctcctcttg gtgacccaat
    62401 tgaggtaaca gtcagagatt atgaactatc aattcgtaag tcagatgcag aaaaaattat
    62461 tgtggaataa taaagattaa ttagagtaga gttaatgtaa ttatataatg agaatgattt
    62521 tctatatcat gaatagtgat gtatttaaat aataatggag ggaatggaaa tgtcaataaa
    62581 aataggtctc ataggaaatc ctaactgtgg taagacaaca atgttcaatg ggcttacagg
    62641 ctcatcacaa tatgttggta actggccagg agtaacagtt gaaaaaaaag gtggaaaatt
    62701 aaaaggaaat aaagatgtgg aaatagtaga tttaccaggt atttattctt tatctccata
    62761 tacattagaa gaagtagtta cacgtaattt tatgctagat gataagccgg atgcagtaat
    62821 aaatattgta gatgcatcaa atatagagag aaatttatat cttacaactc aagttttaga
    62881 gctaggtata ccgaccgtta tagctcttaa tatgatggat attgtaaata agaatggtga
    62941 taagataaat attaaagaac tatctgaagt tataggttgc ccagtggtag aagtaacagc
    63001 agttaaaggt caaggaatta tggaggctgc tgaaaaggca gttgaacttg caagtagtaa
    63061 caataaatta aatttcaaat taccctttgt tgatgaaagt aaggatgcaa tagaaaaaat
    63121 tgaaaaaata atagaagaaa agactccata tatagatgta gaaacacgct ggttagctat
    63181 aaagctattt gagagagatg aaaatgttat acaaaaactt gatatttcta aaacaatatt
    63241 gaatagtatt gaagaaataa ctagaaattg tgaagatgaa ttggatgatg atagtgaaag
    63301 tataataaca gccaatcgtt atgaatttat tagttcaata atttcaagta taataaagaa
    63361 gaatcgaaaa ggtaaggaaa ctgtatcaga taagatagat aagattgtaa caaatcgtat
    63421 actagcatta cctatttttg cacttataat gtggggagtt tactatatag cagtaagttc
    63481 attgggtact atagcaactg attggacaaa tgatgtactg tttggagaaa ttattcaagg
    63541 caatgtaagt aattttctag cttctttaaa tgtagcagag tggttacaag gacttgtagt
    63601 tgatggtcta attggtggag ttggagcagt actaggattt gtaccacaaa tcatgctttt
    63661 attcttatta ttatcaatat tagaagattg tgggtacatg tcacgtgtag cttttataat
    63721 ggatagaatt ttccgtaagt ttggtctttc aggaaaatca tttataccaa tgcttataag
    63781 ttcaggttgt ggagttccag gagttatgtc aactcgtact atagagaatg atagagatag
    63841 aaaaatgact attatgttaa ctacattcat tccatgtgga gctaagattc caataatagc
    63901 attatttgca ggggcattat ttggaggtgc ttcatgggta gctccatcaa tgtatttctt
    63961 aggtattgca atgataatca tttgtggaat tatattaaag aaaactagtt tatttgcagg
    64021 agaaccatct ccatttgtta tggaattacc tcaatatcat attccaagtg caaaaggtgt
    64081 tttaatacat atgtgggata gaggaaaagc atttataatc aaagcaggaa caattatatt
    64141 tgttgcttgt ggagtaatct ggttcttaca atcatttaat tggtcattac aaatggtaga
    64201 tgctggagat agtatattag ctagcttagg aaatatagtt gcaccaatat ttgctcctct
    64261 tggatttgga aattggcaat catcagtagc aacagttaca ggtctagtag ctaaggaaaa
    64321 tgtagttgga acatttggag ttttatttgg tatatcagat gcaacagagc aagacccaac
    64381 acttcttgct tcagttgcaa gcatgtttac agtagctagt gcgtttgcat ttatggcatt
    64441 taatatgctt tgtgcacctt gttttgcagc tattggagcc ataaaaagag aaatgggttc
    64501 atggaaatgg acatggatta cattaggatt ccaaacttta acagcgtata taattgctct
    64561 tcttataaat caagttggaa gtttagtttt aggtactgga ggaagtattg ctggggcaat
    64621 aatatctata tttatagcag tagcagtagt ctttgtagtt ttaacttatt caaataaaaa
    64681 tatgaaaaaa gaaaaaatgg gtaaattaag ttatatgaaa aattaattca tataaataag
    64741 gagtgatgaa tatggctaca tttattatag cagctattgt agtagtatta atggcactag
    64801 ctgtaatgta tatggttaaa aattcaaaaa agaatggtag cagttgtgga tgtggttgtt
    64861 ctggatgctc aagtagtaag agttgtcata gcgctaagag ataaatagga taagagcctg
    64921 ataaaaagtt aaattgcttt attatcaggt tcttattttt tgtataaata acaaatttca
    64981 tatttgaagt aggttagact atgctgtaat tttactgtat aattatatat aaatatatga
    65041 ttaggaggga ttattgctaa attaagcaat ataagtgaat attatgttta aatttgatgt
    65101 tacaaacgag cttatgtgta tagcaagggg aagtggtaaa ttttttgcaa aaaaaggtgc
    65161 tatggtagcc tttaaaggaa attttaattt tgaaaaattg ctgttaggtc caagtaatgg
    65221 cggtggattg ggaagagcat tattaggtca tgttcagagg tcattgacag gagaacaaat
    65281 gccaataatg gtggttgaag gtgaaggtga aatttaccta gctcaaaatg cttaccatgt
    65341 agatgtaata tcaattgacc caggtgattc catttatgtt gagagtgaaa acttattggc
    65401 attttctgaa caattaaatt acagtgtaaa attgattggt tcaggggtaa tatctcaaaa
    65461 aggtcttttt actacacatt tagtaaataa aacaggtcaa aatcaagatg ttgctataat
    65521 aacagatggt aatcctctaa ttcttgaagg accttgttgt gttgacccag atgcattagt
    65581 agcttggact ggaagagaac catatcctaa agtatcaaaa ctatcatgga agacttttat
    65641 tggtcagact tcaggagaat cttatcatat ggaatttgtt gaacctggac aaatagtcat
    65701 tatacaacca tctgaaagat tgtctggctt aaaaacagat tctacacctt ctgatagaat
    65761 gagttcaggt ggattaagac ttggcataga ttaaatctta tgatatagct taattattat
    65821 ttaagatatt aaaaaataaa aagggtagca gggatagata tgttaaaagg agttttatat
    65881 gtttgagaaa attcataaaa ggcttaaagg atattatatt tttttaataa ttttaatttt
    65941 atggaagata gtatgtgttt tgggtatatg gagtagctat attctgcctc ctcctgaaat
    66001 agtcttagat acttttataa aaatgatata tgacggttct attttcttaa atgtttatgc
    66061 cagtgtaaga aggatattaa taggtttttt aataagttca ttgatggcta taccacttgg
    66121 agttttattt ggagtaaata aaaaaatgta tgaatatttc aaaccactat ttgaatttat
    66181 gcgaagtaca cctccactag ctttggtgcc aatgcttatt ttatggtttg gtataggtga
    66241 agaatctaaa attataatta ttattttggc atcctttttt ccaatatttt taaatacatt
    66301 gaaaggtata aaaaattgtg acaataaatt aatagaagta ggtaaatctt ttaatttatc
    66361 taaaaagaga attttttata aaataataat ccctaattct atgctggata ttgttgttgg
    66421 acttagttta gggcttgggt atagttttag ggctataatt ggagcagagc ttattgcagc
    66481 ttcttcagga ctaggatatt tgatttctga tggaaaagat atgtctagaa ctgatgttgt
    66541 attggtagga atttttgtta ttggattttt aggtatactt tcagattatc tattttcaaa
    66601 gataataaca aaatttagca aagggaagca ggttgattta aatggttaga agtggatttt
    66661 tgctagagaa tatatataag aaatatttag ttgataataa agagcattta gttcttgata
    66721 atatatcttt aaatatatct agtgaagaga taactgttat attaggtgaa agtggatgtg
    66781 ggaaaacaac gctacttaga attttagcag ggcttgaaaa tgctactagt ggaaacatat
    66841 atttttttaa taatgataaa aagtgtactc caaaagtagg aatggtattt caagaaagta
    66901 gacttatgcc atggctgaat gtaagtgaaa atatactttt acatactgaa aaagataata
    66961 gaaataaagt tgatttagac aagtatttaa aaatgatgaa gcttgaaaag tttaaaaact
    67021 catatccaaa tgaattatca ggaggaatgg ctcacagagt aagtatagca agagcacttt
    67081 ccttcaatcc cgatattttg ctgatggacg aaccatttgc agcactagat tacttcacaa
    67141 gaagaaaaat gcaaaaagaa gttgtaaata tccataaaaa tactaaaaaa ggtgtagtat
    67201 ttgtaactca caatattgaa gaagctatgg aaatagcaaa gaaaataatt gtttttagta
    67261 aaaataaaag gattaaacaa tttagtgtcg aagatgaata taatagagat ttaactaaaa
    67321 actattatat aaacttgaaa aaagaaatat taagggaatt gggggagttt taattgatta
    67381 aaagaaacaa aaagatttta gcagtaatga catctttaat aatggtgttg gttgggactg
    67441 taggatgttc aacaacaaat gataagaaag atgaacctgc aaaaaaagag gctagtttac
    67501 ctaaggaaat aaatttaact tatgtaaaat caccacttaa tgttcctagt atattagaaa
    67561 aaaaggatga tttatttgga aaggaattta aaaaggacaa tataaaagtc aatttccatg
    67621 aattgacaac aggaccagag caaactcaag cattagcagc aggtgagcta gactttttac
    67681 atgcattagg aggaacgtct gcaataatag ctgcatcaaa tggtgttggt cttaaaatta
    67741 cgaatattta tagccgttca ccaaaaggat atatgcttat aactaataat gataatatta
    67801 aatctataaa agacttaaaa ggtaaaaaaa ttgtaggtcc aaaagggact atacttcatc
    67861 aactgttgat tgctgcactt gctaaagaag gctatactat agatgatgtt gaatatgtaa
    67921 atatggatat tcctagtgct gcttctgcat tagaaagtaa aagtgctgat gtagcaatgc
    67981 ttgcaggtcc agtggcattg aaaacgataa attcaggtgc caaaatgatt gtaaatggag
    68041 aaggattagt aagtggaata atagttactg ctgtaagtga tgactttgct gaaaaatatc
    68101 ctgaattagt aaaaagattt atgaaggttc atgaagaaac tttaaaatat atgaatgaaa
    68161 acaaggatga agtgatggat gttgtatcta aagaagttgg tttatcttta gatgaaacaa
    68221 aagaaatgta ttcttggtat gactttagtt ctaaaataac ggacaaggat ataaaagaat
    68281 tagaagatac acaggaattt ttaatgtcta atggaatgca acaaaagaaa ataaatatta
    68341 aagatatgtt gtacaatcaa aattagaata ctttaaaata ttaaagtgga aaatacaccc
    68401 ttatttatta tggaaactat atggtaaaag agggtgtatt tttattatta tacaaaaata
    68461 caattaaaaa cagcttacta ttttatctac acttatgtag tctagtaatt ttctcatttt
    68521 cttacggtga agtaaaaact tcgaatatgt gtcctcggat tgttttgtgt caccataaac
    68581 tttccaatat ttaatcatag aaacttcata attactatat cccataaatc caatcacatc
    68641 tttaagagga tatcctaaaa aaatacctat ttcatcagga aaaacatcac tcttaagttt
    68701 atctactaaa tgctctaaat aagcattaac attcgtattt tgtttgtatc ctaaaaactt
    68761 taaaaagttt actgtttttt tacattttaa tttttctgat aatgcttttt tatttacaaa
    68821 taagattttt aatccctttt tttctttatc aataactata aaatctattt tcttacattt
    68881 atatagatat ttataaatat cattaatttt ttcctctcta tttacatcag taaacgaaat
    68941 atttattatt tcagcaggtt tagagcctaa aaagactgga cctaaaactt ctaaaagcca
    69001 ttttatatat gatgattcaa ttttattttt acaacaaaat tgtgaattac aacaagacat
    69061 aaaagataac ctccttcaaa tgaaaattaa tatcaagtaa ttagattata ctatgaatga
    69121 taatcaatat caataataaa attataattt ttttatttaa ttatttattc attatgattt
    69181 ccaaaaaaat aaattataac ttgtttaatt ttagtaaata aaatataaaa atatagaaat
    69241 actaaattaa gaaagaaaat tattaaaatt ttttatagta taaaacatct aggagggtaa
    69301 taaaaatgaa attaaaaaga actttatttg taggattagc actagtatta gctataggta
    69361 taactgcatg tactaaaaat aatgaaaaac caagtgaaaa tacaggaaaa aatcctaatg
    69421 aatctgtaaa taataatgaa ggatatatga attattattc aacaagctat aatgattata
    69481 tagcaggtct aaatagatat tctatttatg atactccaga aagtataaat aatcagttta
    69541 aagataaaga atatccagga aatgaaaaat atctaagtga tgtaaaggct gcatataaag
    69601 atagtagaga taaaatacaa tcatttgtaa catctcttaa aaaagatggt aaaacagaag
    69661 atacagagtt aaagaaaatg aatgatgacc taatcgctga aggggaaaga ttagtaaaag
    69721 acatagataa gagaatagaa aaattagata aggtatctga tgaagatatg aaaaaaggtc
    69781 aaaatgactt tataaaatta gttcatggaa ctgaagatgt tggaaatgat ataggtagtg
    69841 gttttagaaa aatgataaaa gatatgaatg atagattagg aataacagga aataataaga
    69901 aataatagaa taaatagttt tgaaatttga aataaattat ttgagatata gcgaagcctt
    69961 ataaataata cattttttgg cttcgctttt ttgcatgtta ttaagatatt aatttttatc
    70021 ttgtaacctt aatattttta ttataattta tttagggatt attttcatac gtttttactt
    70081 gttttttctc tttttaaatt tttgttttgc aaaattgtaa gattctccta ttaaagtttt
    70141 aaagttctca aatgtctttt cagtagggct taggacgcat atccatccca tccatgagta
    70201 gataggatgt ggcatgattg tgtccaattt tgtaaaatca aaatccatat caactatttg
    70261 acctacacct ggacgttttg gaatatatcc aaacatttca ataaaagttt ctttttttaa
    70321 tcctatattc acacggtata catttgggcg actaaccaac gaacctttat catgattact
    70381 gtctttttct ttaatggtaa gaacatatac tcctcgcttt aaaataccat taggattgta
    70441 gtaaattgct cgttcccccc aactattcat taataaaaca tcatctaagt ttgatagaca
    70501 ataattgata atatcatcag ccttaatagt attattttcc ataaagtatc agtcccttct
    70561 ttctttacta ttattattgc tttaaatgta agaatatctt atcatataat agtgacaatt
    70621 attgtcacta tatttaaatt aggagtataa atatgtcaag agctgagcgt ttaattgaac
    70681 tgatgataac aataaatgca aaaagaagtt ttacagcagg agaattagca gaagaatttt
    70741 ctgtatcaaa acgtactata ttaagagact tacaggtgct ggagagtatt ggatttccat
    70801 tatattcaaa agttggagcg gctggtggat atcatgtact taaagagcgt atacttccac
    70861 cgattgcatt ttcagaaagt gaggtaaaat ctatattctt tgcatatcag tcactagaat
    70921 attataatga tttgccattt gagcaagaaa ctatttctgt tttaaaaaaa tttttaaatt
    70981 gtataccaaa tgatattcaa tataatattg agaatataag gcgtaaattt gttttttgga
    71041 caccagatag gcactgttca acaccattat tgaaagaatt gtttaatata gtaatgaatg
    71101 aatctacaat taaaattgaa tattcatcaa agcaaaaaaa tagtgtacgt accattgttc
    71161 ctattggttt gtatgccatg aatggacttt ggtattgtcc agcttactgt ataaaatcag
    71221 catctattaa ggaatttcgt gtagacagaa ttgtgaagat tttgagtata gaaaacttat
    71281 caagtaagaa atataaggtt ttatcttcta tacatgatta tcttaagaat atggaagtag
    71341 gtacagatta tcatattaaa attaatttga cagatgaggg agtaaaacgt tgtgaaacag
    71401 aatttttgtt ggcaagaggg ttgaaaatct tgtctaaagg tggatacata gatatgtata
    71461 taccaaaatc tacacttaac tgggtggctg aatatttttt aacttttggg aaaaatgcta
    71521 caataataga acctatagaa cttaaacatt tggtaaagtc taaagtacta gagctatata
    71581 atcatcattg tatttaaatt attttattta atagtaggat agagtttgga taaaatgtta
    71641 attttcttaa tttactttac agatgattta gatagattga tgttatttaa tttatttctt
    71701 ataatgatgt tctatagtta tatagacatt aaaatataaa gtgttaggag ctagaaaact
    71761 aattaaaaat agttaattaa cgataataaa aaataaaaaa tttaaataaa tttattgaca
    71821 aatactatta atgaatatat catatataac atagcaacaa atgataatag aattaaatta
    71881 aataacgtct tatcaagagt ggtggaggga ctggcccttt gaaacccggc aaccagtata
    71941 ttttatatac attggtgcta aatcctgcaa ctaatatagt tgatagatga gtataaatag
    72001 ctttctaagc ctgagtttat actcgggctt ttattttgtt gtaatacata agagaggata
    72061 aacataaaaa ctgagcagaa tatatgggag gaaattttat gattagcata aaaaatgtta
    72121 ataagtatta tggaaagatt caagtgctta aagatgtaag tattgaaata gaatctggag
    72181 aaatttttgg aataataggt catagtggtg cagggaaatc aacactactg agatgtataa
    72241 acggattaga agaataccaa gaaggcagtg tacttgtttc tgataaagaa gtaaagtcat
    72301 tgaatgaaaa gcaaatgaga gatttaagaa aagagttagg aatgattttt caacactttt
    72361 cattgcttga aagaaaaact gtatttgata atgtagcatt gccattagaa tgttttggat
    72421 actcaaaggc agaaattaaa aaaagagttt tagagttatt agaagtagtt ggaatatctg
    72481 aaaagaaaaa tgataaaccc agaaatctaa gtggcggaca aaaacaaagg gttgcaattg
    72541 ctagagcttt agcactaaat ccacaagtac ttctttgtga tgaagcaact tcagcattag
    72601 acccaaatac tacaaagtca attctttcat tgcttgaaga tataaataaa aatttgggaa
    72661 taacaataat agttgtaact catcaaatgg aagttataaa gcagatttgt ggaagagtag
    72721 caataatgga aaatggagaa gtattagagg taggagatac agaagaaata ttcttaagaa
    72781 atactaaagg acttagaaaa ttaataggtg aagaaagtat aatattgcca aaaggaacaa
    72841 atataaagat actattccct aaagatattt ctaatgaagc tattattacg actatggcaa
    72901 gagaactaaa tatagatgtg tctataatat ttgggaaatt agaacaattt aaagatgata
    72961 ttttaggttc acttattata aacatttcag ataaaagtgg agagcaagta aaacaatatc
    73021 taactagtaa gggcataaga tgggaggaaa tgataaatga atagtttaat tgacttttta
    73081 acaacactat ttccaaatgc attgttacaa actttgtata tggttatagt accaactata
    73141 gtggcaacaa tattaggatt tatattagca atcatattag tagttacaaa accagatgga
    73201 ttaaaaccaa atagcacaat aaatagtgca ttaggattta tagtaaatat atttagaagt
    73261 ttcccattta tgatacttat agttgcaatg attccaataa ctagattaat cgttggaaca
    73321 agtatagggg aaactgctgc aatagtgcca ataactattg gggcagcacc gtttatcgct
    73381 agaattatag aaagctcatt aaatgaagtt gataaaggat tgatagaagc agcaaaatct
    73441 tttggagcta caaaaagaca aatagtattt aaagttatga taaaggaagc tatgccttca
    73501 atagtatctg gaattacatt atcaataata tctatacttg gttatacagc tatggcaggt
    73561 gcagtaggag ctggaggatt aggtaatata gcacttattt atggatatca aagatttgat
    73621 acagcagtaa tggtatatac tgtaatagca cttataatat tagttcagat aatccaggga
    73681 gtaggaaatc tggcttataa gaaactaaaa taaattaatt ataaacattt taaagagggg
    73741 gagtaaaaat gaaattaaag aaattattat cagtagcatt ggtgtcagca atagcaatat
    73801 cagcagtagg ttgttcaaac aaagaggata aaaaaatact agtaggagct tcatcaaatc
    73861 cacatgcaaa gatattggaa gttgcaaaac ctttgttaaa agaaaaagga tatgatttag
    73921 aagtaaaaat atttgatgat tatgtacttc caaatacagc tttagatgaa gggtctttgg
    73981 atgctaactt ctttcaacat attccatttt tagaggaaac tgtgaaggag aaaggatata
    74041 aacttactta tacatctaaa gttcatatag agccaatggg attctattca gaaaaagtta
    74101 agtcattaga tgaattaaaa gatggagctg ttatagctgt gccaaatgat gcaactaatg
    74161 gagctagagc acttaaatta ttagcaaaaa ataaattgat agaagtaaaa gatggagagc
    74221 ttataactaa aaaagatata actaaaaatc ctaaaaatat agtaataaaa gaaatgaatg
    74281 cagagcaatt accaacagta ttaaaagatg ttgacggagc agtaataaat tctaattatg
    74341 ctttaacagc taacttaaat cctactaagg atgcaatagt aatagaatca agtgattctc
    74401 catatgtaaa tataatagct tgtagagaaa ataataaaga tagtgataag attaaggctt
    74461 tatcagaggc tatgaatagt aaagaagtta aaaaatttat acaagatgaa tataaaggaa
    74521 gtatagttcc agctttttaa actgaatata caaaatctac aaaatgagta aaattaaaaa
    74581 tatttactca ttttttttta taactagaaa gtgacaaatt ttttggaaga attgtggtaa
    74641 catatttata ggtaaaacta tataaaaatg aagaagtggt ggggaatatg gaatctaaag
    74701 gaactttaag taagaataag gtctatatac tagctaatgg gttatttttg gttattgcac
    74761 tt
//
LOCUS       DAJMZY010000004        72807 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.004, whole genome shotgun sequence.
ACCESSION   DAJMZY010000004 DAJMZY010000000
VERSION     DAJMZY010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 72807)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 72807)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..72807
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.004"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            36..1232
                     /locus_tag="OE968_000236"
     CDS             36..1232
                     /locus_tag="OE968_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HCP7217553.1"
                     /translation="MKILVLNCGSSSLKYQLIDMNNEEVLCIGLVERIGIEGSILKHE
                     KAGRDDKYVVEQPMKDHKDAIALVLEAVAHPEFGAVKEMKEIDAVGHRVVHAGEKFAT
                     SVVITPEVEEALKECIDLAPLHNPANIMGIDACKAILPDVPMVGVFDTAFHQTMPKSS
                     YLYGLPHELYTKYGVRRYGFHGTSHNYVSQRAAEILGKDIKDLKIVTCHLGNGASIAA
                     VDGGKCVDTSMGFTPLEGLIMGTRCGDIDPAILPFLMRKEGLDADGLDKLMNKESGVY
                     GMTGISSDFRDIEDAAKNGDERAQATLEAYVKKVQKYIGAYAAEMNGLDVVVFTAGVG
                     ENGKAIRADIASNMEFLGMKLDKEANDVRGKETVISTADSKVKMLLIPTNEELMIARD
                     TLRLVK"
     gene            1325..1849
                     /locus_tag="OE968_000237"
     CDS             1325..1849
                     /locus_tag="OE968_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HCP7217554.1"
                     /translation="MKVSIEKINRKETDKIDLNFCEKIDTISYCDEIYKLVSPVNLKG
                     KVSKTNKGLYLDIDVNFTIVDNCSRCLKEVEIPLEYSIQGFLVKEEDYDEDEFEEFDP
                     FIFDGEEIDLIDIIEQTLDFNVPHKVLCSENCKGLCQVCGANLNEEECSCSEITNDEE
                     YIDPRFAKLKDLFN"
     gene            1874..2050
                     /gene="rpmF"
                     /locus_tag="OE968_000238"
     CDS             1874..2050
                     /gene="rpmF"
                     /locus_tag="OE968_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HCP7217555.1"
                     /translation="MAVPKRKTSKSNTKMRRAANSKMEATGFVSCPQCHEPKLPHRVC
                     PDCGYYKGKEVVSK"
     gene            2257..2814
                     /gene="fapR"
                     /locus_tag="OE968_000239"
     CDS             2257..2814
                     /gene="fapR"
                     /locus_tag="OE968_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription factor FapR"
                     /protein_id="HCP7217556.1"
                     /translation="MKKKSKAQRQKELIDMLKTDPFYTDEELSSLFDVSIQTIRLDRM
                     SLNIPELRERVKSIAETQSSKVKTLGVKEITGEIIDLSVGRLGISMLEVTQDMIYSKT
                     NTLKDTYIFSLADSLAMAIIDAPKVIMRVANVKSFKLIEQQDRLIAKAEVYRNIDKKH
                     YVKVVINNKAQEQIFRGKFIFEELD"
     gene            2825..3847
                     /gene="plsX"
                     /locus_tag="OE968_000240"
     CDS             2825..3847
                     /gene="plsX"
                     /locus_tag="OE968_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HCP7217557.1"
                     /translation="MKIVIDGMGGDNAPKSNVEGAVNAIKEYQVDLIITGDKDLLEKE
                     FSNYEFDRNKLEIVHTTEIIENEDKPVKAIRSKKDSSMVVALNLVKEGKADAIISAGN
                     TGALLAGGLFVVGRIKGIDRPCLCSAIPNVKRGMTLIADCGANADCKPKNLVEFAAMS
                     NIYSRKVLGLENPKVALANVGLEEGKGNDLVKRSYEEIKKLDLNFIGNVEAREVINAY
                     TDIIICDGFTGNILLKSAEGVALSVMSLIKETFMASTKSKIGALLIKDDLRKLKSFID
                     YSEYGGAPLLGLNGGVIKAHGSSDAKAIKNAINQGIKFSKGKVVEDINQFISKYNEEN
                     KNNEDE"
     gene            3873..4859
                     /locus_tag="OE968_000241"
     CDS             3873..4859
                     /locus_tag="OE968_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HCP7217558.1"
                     /translation="MNTKAGILGVGSYLPEQSYDNFHFEKIMDTSDEWISTRTGIKER
                     RFAKESEATSDLASKAALKAIECAKLNVEDIELIILATITPDMSLPSTACIVQDAIGA
                     VNATAFDISAACSGFVYGVTIAKQFVETGCYKNVLVIGAETCSKFLNYDDRTTAVLFG
                     DGAGAAVIGPVNEGGILSTHMGSDGKGKDCLKVPAGGSRLKASKETVEANLHTIEMAG
                     SDVFKFAVRKMAETSLRALEKANLNTTDIDYLVPHQANIRIIQASSKRLELDMKKVYV
                     NIDKYGNMSAASIPVALDEAYREGKIKKGDNVVLVGFGGGLTWGASVVKWTL"
     gene            4968..5897
                     /gene="fabK"
                     /locus_tag="OE968_000242"
     CDS             4968..5897
                     /gene="fabK"
                     /locus_tag="OE968_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HCP7217559.1"
                     /translation="MNKICKILNIKYPVIQGGMAWVATASLASAVSNAGGLGIIAAGN
                     APKEAIKKEIVECKKLTDKPFGVNVMLMSPFVDDIIDLIIEEKVQVITTGAGNPAKYM
                     DRLKEAGTKVIPVVPTIALAQRMEKLGATAVIAEGTEGGGHIGELTTMVLVPQVADAV
                     NIPVIAAGGIVDGRGIAASFALGASAVQVGTRFICSEECSVHSNYKNLVLKAKDRDAI
                     VTGRSTGHPVRTLKNKLSKEFLKMEQNGATPEELDKKGTGALRFATVDGDIEKGSFMA
                     GQSAAMVKEITPCKEIIEAMVNQAREIMPAIEL"
     gene            5913..6863
                     /gene="fabD"
                     /locus_tag="OE968_000243"
     CDS             5913..6863
                     /gene="fabD"
                     /locus_tag="OE968_000243"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HCP7217560.1"
                     /translation="MGKVALVFPGQGAQYVGMAKDLYENNTVAKSVIDEASDALNMDL
                     KNLMFNGNEEELSKTENTQPAMVTHSVAVLKAVQAQVDLKYSACLGLSLGEYSALVAA
                     DAIDFKDAVCLVKKRGKFMQDTVPTGVGAMAAILGLDRSILENVVKDIQGGIVEVANY
                     NSPGQIVISGENEKIEEAMVKCKEAGAKRAVKLNVSGPFHSSMLREAGVKLASELEKV
                     NITKPKVDVVANVNADYYKNEGKDLLIKQVSSSVLWEDSIERLLNDGYDTFIEMGPGK
                     TLKAFIKKIASNKKANVNIYNIDGIDSLNEFVQNYRNGEI"
     gene            6863..7612
                     /gene="fabG"
                     /locus_tag="OE968_000244"
     CDS             6863..7612
                     /gene="fabG"
                     /locus_tag="OE968_000244"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HCP7217561.1"
                     /translation="MINLTGQVAVVTGGSRGIGKEIAKKLASFGADVVINYTSKEDEA
                     LKTKNEIESMGVKCTSIKCDVSKFDEVNQMIDSVVSEFGKIDILVNNAGITKDGLLMR
                     MKEEDFDRVIDINLKGVFNCTKAVTKPMMKKKYGRIINMTSVVGIMGNAGQTNYCASK
                     AGVIGFTKASARELASRNININAVAPGFIETDMTKVLSDDVKESTLANIPKKSYGKPE
                     DVANAVAFLVSDMSSYITGQVINVDGGMVMQ"
     gene            7666..7890
                     /gene="acpP"
                     /locus_tag="OE968_000245"
     CDS             7666..7890
                     /gene="acpP"
                     /locus_tag="OE968_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HCP7217562.1"
                     /translation="MFNKVVEIIIEQLGVEDKEITMETSLMKDLEADSLDAVEIIMAL
                     EDEFGIEIPDTEAENFKSIGDIVKYIEANK"
     gene            7919..9157
                     /gene="fabF"
                     /locus_tag="OE968_000246"
     CDS             7919..9157
                     /gene="fabF"
                     /locus_tag="OE968_000246"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HCP7217563.1"
                     /translation="MNKRVVITGLGCVTPLGTGKEEFWSNIKSGVSGIDKITNFDAST
                     YQTQIAGEVKNFHPEEYISKKELKRLDKFAQFAIVSAKLAVEDANLDLDKVDRERFGV
                     IIGSGIGGVEAIETQHKILLEKGNKRVSSLFVPMMIGNMAAGQVSIFLGAKGPNTNVC
                     TACASGTHSIGDAFKVIQRGDADIMVAGGSEAAVTGLAFAGFCNMKAMSTRNDDPKTA
                     SRPFDKDRDGFVMGEGAGIVILEDLEHALARGAKIYAEVVGYGLTADAYHMTTPAENG
                     EGAARSMNMALKDGNVPLEEVDYINAHGTSTYYNDLYETMAIKTVFGEKAYDLCVSST
                     KSMTGHLLGASGAIEAVVCAMSIEDSFVPPTINIQEVGEDLDLDYVPNQGKEKNIRYA
                     LSNSLGFGGHNATIVLKKYV"
     gene            9383..11101
                     /locus_tag="OE968_000247"
     CDS             9383..11101
                     /locus_tag="OE968_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HCP7217564.1"
                     /translation="MNFRLPKKRLPKKIIFICIILISIILFIKHDQNGLKEREIINKG
                     KYMSESLVADKEYDEAKKVVKTSFESIPEKKYNKVYNEVWDMLKTISYVPDGTKIVID
                     SLEKMRESDVKLSDECRFNIEKRLASVYIMDNNYSKAVDLTVKSIKLAEKLGNNYEKA
                     RLDVDLASIFLKIGGYETGEKLIKDSFKIDIDEGEKNGMVRLYAIINLAEIYVEEGEY
                     DKAIEISSRIKDYKKFVNTDNYNDFDIMASIMQSNAYVGKNNIQKAKTFLEKADYLIK
                     SDRTVYILDKDMYYYMAMGNLEYKSENYNSAIDNYKKSLEISTKRKLTQEKIKNLNKI
                     LNIYEKQGNIESLNEYQKMLINEYKENKSIRDSETSFYIIDKVSNESKLFEKTKKEIK
                     YYKILFTVILIAILGSTFLYNRLKYFKAQNLHDGLTNVYNRKSFDIMYEKYREKDDNF
                     ALVMIDIDNFKLINDNYGHKFGDTVIKGITNTICVMLEQDDKVFRYGGEEFSVLIRNK
                     SGDEVADIIDSIRVAIANKKWNDDVTVTISAGVAHVSDSKDVLEEADKNLYKAKQLGR
                     NKVVYK"
     gene            11132..13132
                     /locus_tag="OE968_000248"
     CDS             11132..13132
                     /locus_tag="OE968_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HCP7217565.1"
                     /translation="MKQSIAIVTDKITKLSSFLEENIRLVLGNYIDINHYYLEVLKEN
                     DKIQGDFVLVMNDDRLNSMRKHLVQDSKIIVIRRTLKENEIYGLFSIPNGTEVLVVND
                     TKETTLETISLFYKIGVKNLKFTPYIEGKIYKNIDIAITPGVKGKVPSYINKVIDLGN
                     RYIDISTFIEIINGLRIDVKEIRKNLMAYSESLISLDNGVKDNYRQLFLKIEEQDVIL
                     NLSKDGIIFTSADGIINTFNKEALKILGINENPQGKNIEDIISEDLNILLEDKEIIDE
                     VVFTNKKYINVNKKSIFSMGNKAGIYYNLQEITYIKKLEQNLTNKLREQGQIARYTFK
                     DIKTKNKNMVKCVELAKKISKSELSVLIIGESGTGKELLSQSIHNASNRSNQPFIAVN
                     CAAVPDSLLESQLFGYEKGSFTGALREGKKGLFELANNGTIFLDEIGDMPPLLQTKLL
                     RVLQEKQVMPIGSHNVINIDVRVIAATNKNLLKMIREGKFREDLYYRLNVLPIDVPSL
                     RNRKEDIITLMNFFLKNNIRLSPEVITILEKYNWPGNIRELQNVASYVSLMCDSMVFR
                     DDLPPYIRVECANNYEDGFGYTRKEFEEILRILYERRESSSGIGRGFIIEKLIQEGIE
                     ISESKVRKVLSYLSECGYISSKSGRGGSQITSEGIKLYNNIN"
     gene            13483..13728
                     /locus_tag="OE968_000249"
     CDS             13483..13728
                     /locus_tag="OE968_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03905 family TSCPD domain-containing
                     protein"
                     /protein_id="HCP7217566.1"
                     /translation="MKYKTTGTCATEIEFEVKENKVTNVNFIGGCDGNLKGLKVLVEG
                     MNIEDVIQKLKGIECKTKPTSCPDQLSLALENYMNIK"
     gene            13763..14488
                     /locus_tag="OE968_000250"
     CDS             13763..14488
                     /locus_tag="OE968_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HCP7217567.1"
                     /translation="MKPIIGILGNLIIMENGMFPGLERSYVNNDYINAVLKGGGSPVI
                     IPVNTDKEVIKKQIEMVDGVLISGGWDINPQLYGEETREETTFIYPEVDEFDLIAISI
                     ALELKKPILGVCRGLQILNVSLGGTLYQDNNLIEGSYIKHTQSSKRHVATHKVDVKEG
                     SILEGILGKQLLTNSYHHQSVNQLGKGLKAIAYSKDGIIEAIEKEDENFVVGVQWHPE
                     MMVDYCDKMEKLFKYFINICSNL"
     gene            14510..15823
                     /locus_tag="OE968_000251"
     CDS             14510..15823
                     /locus_tag="OE968_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCP7217568.1"
                     /translation="MNEKNKMGLISIILLGINAVVGAGVFLLPGDAMKSFGVASIFVY
                     IFDMLLVLSMAFCFAEVAGKFNKNGAAYVYTKEAFGDFCGFEVGLMKWVIGCISWGAL
                     IVGFPTSLSAVWAPAGEPHIQKIIIVVMIVGLTIINLLGVSLSKIVQNVITVGKLIPL
                     ILFIGIGIFFIKGVNFTSSTMVPPGAGATEFGAAALLMFYSFTGFESIAVAAEDMENP
                     QKNIPIAIISVIVIASIIYILNQVVCVGILGDSLSSTSTPVADAARICFGNMGAGLVT
                     FGTLVSVGGICMCGAFVNPRSCVALADDKMLPRIFARKDKKGTPYVAIIATMLITIPI
                     ALSGSFAELAAISAVARFIQYIPTSLSVLVFRKKRPELVGTFKTPFGAVIPLIAVCVG
                     TWLLFQASMHQLIMGLGALAIGVPLYFIMKSYNRKVYDENLKKIV"
     gene            16029..16568
                     /locus_tag="OE968_000252"
     CDS             16029..16568
                     /locus_tag="OE968_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCP7217569.1"
                     /translation="MPTITLKNGVDVLIREGVREDAQSIIDFYNEVGGETHFLSFGKD
                     EYKISLEEQENAIESAKASDNSVKLIAFIDGEIVGIATIDSNQKAKGKHVGVLGIVVK
                     EKYWGIGLGKRLMLDLIEWCKSNGITKKITLVTNEENYNAIGLYKKVGFEVESILKKE
                     CYYNGVYTDLIGMSLLLGI"
     gene            16657..18642
                     /locus_tag="OE968_000253"
     CDS             16657..18642
                     /locus_tag="OE968_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-1,6-bisphosphatase"
                     /protein_id="HCP7217570.1"
                     /translation="MKNLCKISDDYLNSKLKYLKLLSKQYPSISKASTEIINLEAILN
                     LPKGTEHFITDVHGEYEPFVHVLKNGSGVIKRKIEELFSNTIRDSEKKMLATLVYYPE
                     QKLDLIIKQEENIDDFYRINIYRLIELCKYASSKYTRSKVRKLLPENFKYIIEELLHE
                     HVKSEHKEEYYKSIVETIVDIGIAKEFIIAISTVIQKLVVDRLHVIGDIYDRGPRPDI
                     IVDKLIEHHCVDIQWGNHDILWMGAASGEKTCIANALRISARYANLDIVEDIYGINLL
                     PLATFAIEMYKDDPCKEFIPKVNDQSVTTTEKSLMAKMHKAISIIQFKLEGEVIRRRP
                     EFEMEHRLLLNMINYDEGTINLKGKTYKLKDTYLPTIDKKDPYKLTMEERNVIDKLVS
                     SFRGSEKLQKHVSFLFSKGSIYLKANSNLLIHGCVPLNEDGSFMSMNIMGKEYKGKAL
                     MDKMESLAREGFFFKDKAEEKLYGMDIMWYLWTGKCSSLFGKDDMTTFERYFIAEKET
                     HKENKNPYFKLRENEMACKRLFEEFDLELDESHIINGHVPVESKNGESPIKANGKILV
                     IDGGFSRAYQKTTGIAGYTLIYNSRTLQLVSHEPFNSAEEAIANESDILSTTVVVEHK
                     AKRKMVRDTDEGVKIQEEIEDLKLLLMAYKKGLIKEM"
     gene            18866..19834
                     /gene="spoIIIAA"
                     /locus_tag="OE968_000254"
     CDS             18866..19834
                     /gene="spoIIIAA"
                     /locus_tag="OE968_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AA"
                     /protein_id="HCP7217571.1"
                     /translation="MNKLSDEIINSLSTTIREKVEKVSNNNLNIEEIRLRSQKPLILN
                     ANSKDYFYNQKTMTLDLNQQNSYVVTREDVEQTFQIICKYSIHSFMDDIKKGFITLRG
                     GHRVGLVGKAIVEDGQVKNIKHISSLNIRVSREIIGCSDKILSHIIKGKNQINNTLII
                     SPPQCGKTTLIRDIVRNLSNGNEDYGFKGLKVALVDERNEIAGAYLGVPQMDVGIRTD
                     IIETCPKDLGITMLLRSMSPNVIVTDEIGSEKEIKALYTALNGGIGLITTVHGDSIED
                     IQNRKELNRLLDKELFKKVIILSAKRGAGTIEKIYDLEEKRWYFAN"
     gene            19824..20345
                     /locus_tag="OE968_000255"
     CDS             19824..20345
                     /locus_tag="OE968_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AB"
                     /protein_id="HCP7217572.1"
                     /translation="MQIKIIIIAFLIGSSYLIGEQIYKTYTRRHKQLNDLIRVLEILR
                     MDLSFGLYTLEEIFNRIGGNKEFCFWKFFYQISEGLHNEQSKTLEIIISENIDVLSKE
                     TYLGNKEIEELKNLILTLGKSDIESQQRMIDLSIENLKKQTYETKEDINKKGVLYKKL
                     VTFIGIGICIILI"
     gene            20362..20559
                     /gene="spoIIIAC"
                     /locus_tag="OE968_000256"
     CDS             20362..20559
                     /gene="spoIIIAC"
                     /locus_tag="OE968_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018589775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AC"
                     /protein_id="HCP7217573.1"
                     /translation="MEISLILKVAGVGILISVLNMILEKTDRKDWAGLTTLAGVIIVL
                     GMVITEISDLFNTVRTMFQLY"
     gene            20575..20961
                     /gene="spoIIIAD"
                     /locus_tag="OE968_000257"
     CDS             20575..20961
                     /gene="spoIIIAD"
                     /locus_tag="OE968_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AD"
                     /protein_id="HCP7217574.1"
                     /translation="MEIMQLIGIAIISTTLCLVIKKDRPEIANFIAIITGVIILLSVM
                     FKLNFIVDSIQDLANKANIPTMYISLIIKLIGIAYLMEFAIQLCKDCGEGNIASKLEF
                     GGKIIVMSMSFPILLSIVEMVVNIIP"
     gene            21046..22251
                     /gene="spoIIIAE"
                     /locus_tag="OE968_000258"
     CDS             21046..22251
                     /gene="spoIIIAE"
                     /locus_tag="OE968_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AE"
                     /protein_id="HCP7217575.1"
                     /translation="MKKRFLPMIIGFLFTFFFVNIFAIMIFANEVPSSEDKEYGETKN
                     SIDKYIDGQLDKLDINEIQDYINKEIVINDVNLKSFVKDLISGEKNILDLFNKDGLKI
                     LMFDEFKASLKVVAVILVLALLSSILKSLENSFSSGAVSQIATYIIFITMVSLTLIGF
                     KDVLQICYDAIDHTVGLMQVIMPILITFLLLIGFPITSTTLNPIFIGGVTFINVFFKN
                     FLFVSITVAFGILIINNLSKNIRLKRFFSFVKQINYVSIGAMFTVYLGLVSIQGLYVT
                     SFDKFSVKTAKFAIGNFIPVVGGFVSDSVDILLSSSQLIKNIFGGIGLILLVGICLLP
                     VIKILSVIVVYKLAAIIVEPVGEDGISNFLNEVANLMIIMLASVIAITVMFFVTVAIL
                     TSISVVSQG"
     gene            22311..22928
                     /locus_tag="OE968_000259"
     CDS             22311..22928
                     /locus_tag="OE968_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AF"
                     /protein_id="HCP7217576.1"
                     /translation="MLEGIKAWIVSVLIGAFIVNIVDMILPSSKIKPYVNLVLNFMFV
                     FIVITPVVGFFSKDMSLEDRILKSMGNYNKQYVDSTNALAKETGNNSLSKGYEDGLKE
                     VLKLKLDEYGYDLEDIELNGANINNIKIKEKNNSAKSNNSSNEENKNNSTKREEENIN
                     SNDKENSKQVFKKGTEYGLNLNEEKLKNDLIKVLDVSIEDIQIDK"
     gene            22940..23494
                     /locus_tag="OE968_000260"
     CDS             22940..23494
                     /locus_tag="OE968_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AG"
                     /protein_id="HCP7217577.1"
                     /translation="MLKNLNDKDKRKVYSLITIAGICVVSLVLLSCFPSSKSDKQVGK
                     TETNKNAEKQVTKEQEKDDLESKLTAILSKIDGAGDVDVMVTFESSEEIQPAFNSNNT
                     TETTEEKDAQGGERTVTTSSENKTMITSNSSDPVVIKTTEPKIKGVIVVASGASDPSV
                     KETLYSAVQTSLQVAGHQVEIYSK"
     gene            23521..24210
                     /locus_tag="OE968_000261"
     CDS             23521..24210
                     /locus_tag="OE968_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpoIIIAH-like family protein"
                     /protein_id="HCP7217578.1"
                     /translation="MKFNYKGRGFVIITLTAMLVVVGTVNYQLSKKSLLETSKEFKAY
                     EEAQLQKNTDDSYSSKTEDSSNVDKQGGKESADIDIVDSKASKVKEKATETSKEIKAQ
                     LSSEKNMKKASYILDMKMNREKQRNELVQDLNEMINNPSTTEESRKEASNMKLNIVKI
                     QEKELQIENLLSTKGYEEALVYISDNKVNVVVNEAKLEKKDAAKIFDLVAEQANVKYE
                     NIKLTNNNSNK"
     gene            24320..24682
                     /locus_tag="OE968_000262"
     CDS             24320..24682
                     /locus_tag="OE968_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HCP7217579.1"
                     /translation="MEDNKFGQVKISNDVIATIAGLAALEVEGIETTATLTDKLLKNN
                     GVKIQIEEEDVNLDVMVTIKYGMSIPDTAFKVQENVKNTVETMTGLKVSQVNIHIQGI
                     SFKKDKVDKEEAKATKKN"
     gene            24767..25273
                     /gene="nusB"
                     /locus_tag="OE968_000263"
     CDS             24767..25273
                     /gene="nusB"
                     /locus_tag="OE968_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HCP7217580.1"
                     /translation="MKKDRAQKSTTREYIMKLIYQININKEDFETLEDKVDNFLKDNS
                     EHIINRYKELALQYSKNTNLKLEDTEIEDVIDKKYINTVCKALKENHDKIDELINKHA
                     KNWTVDRMPKVDVSILRLSVCEILYLDTPNKVSINEAVELAKIYCDDKSPKFINGILG
                     SVVDEIGK"
     gene            25257..26327
                     /locus_tag="OE968_000264"
     CDS             25257..26327
                     /locus_tag="OE968_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-sialoglycoprotein endopeptidase"
                     /protein_id="HCP7217581.1"
                     /translation="MKLGNNIIIGIDTSCYTTSIAAISLDKKVIFNEKIMLEVRDNSK
                     GLRQSEAVFQHINNLGILSDRIKSFKDKFNVEGVCSSKKPRPVENSYMPVFNVGHNFG
                     KLLSSIYGCRFYETTHQENHIEASLLNSKLKNNNKFISVHMSGGTTEILLTSKQDSHH
                     NVCDTNLGKIAKISIKKDDKSKLYNNFGYNIDIIGGSKDISFGQLIDRVGIKLGYKFP
                     SGKYLDENALNCNLKIESGLKTSVRDGYMNLSGLENQVNKIINDNGDNTNQKEYISKL
                     VLDSVVRNMFKSLVYLCETYNVNEVVFAGGVSASKYILRELSMKLRKKHIEAYFTEPQ
                     YSTDNAVGCAIIGLNNFLGERV"
     gene            26324..27529
                     /locus_tag="OE968_000265"
     CDS             26324..27529
                     /locus_tag="OE968_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HCP7217582.1"
                     /translation="MKLRALDISEANSYIKRILINDPILSNLKVKGEISNFKVHSSGN
                     VYLSLKDETSKLNCVIFKSNFNRNLKLDNGVKIIANGYISVYERDGAYQLYINEIEIE
                     GIGNLHIEFNRLKEKLNKEGLFDPKYKIPIPKMPNSIGVITSPTGAVIRDIINVIKRR
                     YPKVNIKLYPVTVQGDKSAEEICEAIRFFNHMKNVDTLIVGRGGGSIEELWSFNDEMV
                     AREVFNSQIPIISAVGHETDFTICDFVSDMRAPTPSAAAEIATPSLDDINYKLGNIKS
                     RMSKSLTNQIELDQYRLETVFNKINNYLDSYTIKDKVIQLDKIYDKIIFGIENNLKLE
                     DEKLVKIGALLHNLSPLATMDRGYSITQKNGKVINSIKGLKIKDSIDIVLKDGNLECM
                     IDKIENKEG"
     gene            27531..27746
                     /gene="xseB"
                     /locus_tag="OE968_000266"
     CDS             27531..27746
                     /gene="xseB"
                     /locus_tag="OE968_000266"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HCP7217583.1"
                     /translation="MNLTYEEAYKRLESILSELESKNASLDESLSLYEEGISLYKHCN
                     KLLDDAKLKISKFNQLGIEEDFKIEEE"
     gene            27749..28636
                     /locus_tag="OE968_000267"
     CDS             27749..28636
                     /locus_tag="OE968_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HCP7217584.1"
                     /translation="MEFKQCLKEKASFVEKVLKEYMPKEEGYQKTVIEAMNYSLSAGG
                     KRLRPILTLEACKIVGGNEDEAIPFAIAIEMIHTYSLIHDDLPALDNDDLRRGRPTNH
                     KVYGEAMGILAGDALLNYAFEVMLAGSINKENPEKYLKAINEIAKGAGIYGMIGGQVV
                     DVESENKQIEKEKLDYIHMNKTAAMMVGCMRAGATIGGANSEQMEEITKYAKNIGLSF
                     QIVDDILDIVGDEAKLGKKVGSDIENHKSTYPSLLGLDKSKEIAHNLIDEAKKSIEKL
                     SDDVDFLKGLAEYIIDREY"
     gene            28666..29103
                     /locus_tag="OE968_000268"
     CDS             28666..29103
                     /locus_tag="OE968_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divergent PAP2 family protein"
                     /protein_id="HCP7217585.1"
                     /translation="MDFFSEIFNNGALGISLIACFLAQFIKIFTGKEKRIELSRILIS
                     GGMPSSHSSFVTSLATVVGIEKGFNSTDFAIITVLALIIMYDAAGVRRAVGKQATILN
                     QMVADIQHGKHIEQKKLKELIGHTPLEVWFGALLGIVTALILM"
     gene            29137..31002
                     /locus_tag="OE968_000269"
     CDS             29137..31002
                     /locus_tag="OE968_000269"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HCP7217586.1"
                     /translation="MYKYLDKVNSPKDIKNMSIEEMDLLAKDIRKFLVKSVSKTGGHL
                     ASNLGVVELTLALHKVFDSPKDKIVWDVGHQSYVHKIVTGRKDCFVSLRQFNGLSGFP
                     KENESPHDIFDTGHSSTSISIATGIACARDIKKENYSVISVIGDGSITGGMALEALNQ
                     LGYIDTNMIVILNDNEMSIDKNVGGMSKYLSSIIRNSTVEKMTDEVDKILNVTQTGEI
                     LSKTAHRFKDKLMYSFSPQDCSFFDSLGIRYYGPIDGHNTKELIDILRKAKHKKGPVL
                     LHVITKKGKGYRFAEEQPDKYHGVSKFDIKTGVTSAKVKSMSISVGEKLVDMANSNEN
                     IVAITAAMPSGTGLNLFESAYPKRYYDVGIAEQHATGFAAGLAKNGMKPYFAVYSSFL
                     QRAYDQVIHDVCITKKPVTFLIDRAGLVGNDGETHHGMFDLSYLNSIPNIVVMAPKDT
                     REMELMMDLSLKLDCPLAIRYPRGSSYYLDKGEYGEIVLGKYEVLDDGQDTVILCIGS
                     MVKHALEAKEILSREGINPTIVNARFLKPIDEGMLKALLKNHKNVVTIEDNIVTGGFG
                     SRINKFIIDNEYNVNILNIAIPEEFVKHGNIDELYDFVGLSPKSIADKIRKLVIE"
     gene            31135..31947
                     /locus_tag="OE968_000270"
     CDS             31135..31947
                     /locus_tag="OE968_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family rRNA
                     (cytidine-2'-O)-methyltransferase"
                     /protein_id="HCP7217587.1"
                     /translation="MKKRIDLLLVEQGYFESRERAKKAIMAGLVFVDNQRCDKAGTEV
                     KEDCSIEVKGNPIPYVSRGGLKLEKAMKNFDLTIDGKVCMDIGASTGGFTDCMLKNGA
                     IKVFSIDVGYGQLAWKLRQDDRVVCMERTNIRNVTIEDTKQFADFASIDVSFISLKLV
                     LPKAKELVRHDGEVVALIKPQFEAGREKVGKKGVVREKSTHIEVIKMISDFSVENGFE
                     ILGLDFSPIKGPEGNIEYLIHLRNGNEGYEFDGETYNNKIVEVVEASHNLDK"
     gene            31967..33646
                     /gene="recN"
                     /locus_tag="OE968_000271"
     CDS             31967..33646
                     /gene="recN"
                     /locus_tag="OE968_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HCP7217588.1"
                     /translation="MILELYMKNCALVEELRLNIDKNLNILTGETGSGKSIIIDALGL
                     CLGDKYDRSFLRKGTDKGLVEAVFFSDNRYLKKILEENDISMEDDNLLVITRLIYSDG
                     KSTARVNGRTVKVSLLKEIASTLIDIHGQHQNQALFNKDTHLKFLDLFGENELEEFKI
                     AYKNVYHKYSEVKKALNCLTENKDEMQIQREIDLLRFQINEIEAANLNKNEYEDLLKQ
                     REVYRNSEKIYNNLNSSYSKLHNGEYNVIDLIGLASKELNDISKYDSVLSEYSDTVER
                     IMYELQDISGEIRNYKDNIDFEPYELEQIELRIDEINNLRRKYGDSIDDIFEYYGKIK
                     DRLDEILNRDERVEQLRSKLMNIEEDLKIKASKLTKARIEVATTLEKILLDELKSLNM
                     KNVMFKVNFEKGPFTLDGVDDIEFMISFNLGEDIKPIYKVASGGEMSRFMLAFKTILA
                     DIDDIDTLVFDEIDTGISGIAAQIVGEKLSDIAKKKQIICITHLPQIAANADTHYCIE
                     KDTSNNRTFTNVSKLNESQRKNEIARLIAGNNITEKTIEHASEIIELAKKC"
     gene            33861..34727
                     /locus_tag="OE968_000272"
     CDS             33861..34727
                     /locus_tag="OE968_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7217589.1"
                     /translation="MNKKDTMHLIFIIVIFILLWYIVVAVSEINKNIESCSNKLDYLS
                     QELMSTKSDISNTINEEMSKSYITKSIDLKVKKIEKKECIIDIDVQLSKLGKNGKVFF
                     MYKEDSDKWNETEMTKHGELSYACEIKINTGSEYDYKVVTSGAISESSDVQKLTKSDY
                     MPEQPIFNSGIRDNREYFIEIVENSNLFNHESEKSKNKVYDNIRLEKVDIIVNEGKKD
                     TIYKAKLAEGLDDGKTNNSNRNQVNYEVSFPKRDIDDIIYIKAKLTYNNGVEYTKDIT
                     EDITMGLQDLEK"
     gene            complement(34820..35311)
                     /locus_tag="OE968_000273"
     CDS             complement(34820..35311)
                     /locus_tag="OE968_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCP7217590.1"
                     /translation="MADKMAQNITLQFVEEKDLENLENVKLLFTEYSNSLNIDLCFQD
                     FNNELKTLPGKYKKPSGSLILAFVDENLAGCVALKKLEGKICELKRLYVRNQFRGLKI
                     GKILLEEIIEEAKKFGYTHMRLDTLPSMKSAQGLYEKFGFYDIEPYTYNPIEGARYME
                     LKL"
     gene            complement(35372..35812)
                     /locus_tag="OE968_000274"
     CDS             complement(35372..35812)
                     /locus_tag="OE968_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCP7217591.1"
                     /translation="MKLNVRIADINNWHDLVSLSVDKSQLDYIESNALSIAESKFITA
                     WVPVGIYDENSLIGFAMYGRLEDDRVWLDRFMIDSKYQGKGYGKASLDFLVNHLKNEY
                     NCDELYLSIFEDNKMAIKLYKDFGFEFNGELDYGGEKVMVLKSN"
     gene            35973..37031
                     /locus_tag="OE968_000275"
     CDS             35973..37031
                     /locus_tag="OE968_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S55"
                     /protein_id="HCP7217592.1"
                     /translation="MNKINKNFKNIWIILGAVSIFTMVIIFNKNCNVNKETQIEAFTI
                     KNHDKKFVYPMGNIIGVKANTDGVLVLGYEEEDVDYIGGIQIGDNIVKIDNKRIKNSQ
                     DVSEILNKIKKSKVEVTFERKNKYKTEVIETKKENGKYKLGLWVRDKISGIGTMTFYD
                     PSMEKFKAIGHAIKDSDTNELLKIKQGYIYKPEQLKIVKASNEKVGKIKGDFNDSNLM
                     GNFSNNSELGISGNITENHNKEFNVANKEKQLIEVGRPQDVKIGGAVILFEDKNKNIT
                     SYDIKIESIVYDKGNYRDMVIKVVDDKLLEYTGGIVQGMSGAPIIQNNKIIGAITHVF
                     RDNPKKGYGIFIDEMIKL"
     gene            37173..37997
                     /gene="spo0A"
                     /locus_tag="OE968_000276"
     CDS             37173..37997
                     /gene="spo0A"
                     /locus_tag="OE968_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation transcription factor Spo0A"
                     /protein_id="HCP7217593.1"
                     /translation="MGGFLVEKIKIVLADDNKDFCQVLKEYLSNEDDIDILGIAKDGI
                     EALDLVKKTQPDLLILDVIMPHLDGLGVIEKLNTMDIPKMPKIIVLSAVGQDKITQSA
                     INLGADYYIVKPFDFVVFINRIRELVSNRVTQVEPKPRPVQETQMTRSDFVKNVGNIE
                     TEITNIIHEIGVPAHIKGYLYLREAIKMVIDNVELLGAVTKELYPSIAKKFNTTPSRV
                     ERAIRHAIEVAWSRGKVDTINQLFGYTVHNTKGKPTNSEFIAMIADKLRLEHSMVK"
     gene            38410..39531
                     /locus_tag="OE968_000277"
     CDS             38410..39531
                     /locus_tag="OE968_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7217594.1"
                     /translation="MRVEAPIKVDRKTKKLAKRVESGEIAVINHIDIDEVAANSLVEA
                     KIKLVINAAPSISGRYPNKGPGILTENNILIIDNVGEELFEELKEGETIEVVDGKIYR
                     KGKFLGAGEVLDKYEVSHQIKAAYENLAVELDRFIDNTIDYAKKEKGFILGEVEIPKV
                     KTNYANKHVLIVVRGQDYKEDLSTMLSYIEEVKPVLVGVDGGADALIEFGYTPDVIVG
                     DMDSVSDEALKKASEIVVHAYTDGRAPGLKRVEELGLDAVVFPAPGTSEDIAMLIAYE
                     YKAELIVAVGTHSNMIDFLEKGRKGMASTFLVRLKIGSKLIDAKGVNLLYRSKLKIKY
                     IWALIATALFPVLVVASLSPGVQQFIQLMQLKFRVLLQM"
     gene            39549..40424
                     /locus_tag="OE968_000278"
     CDS             39549..40424
                     /locus_tag="OE968_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper transporter"
                     /protein_id="HCP7217595.1"
                     /translation="MHINMKYYIVTIGAIFIALGIGMLVGFNLNNNQQLSEQQANIIN
                     DLDDKFDILKEKNDKLDSDLASVNRDYEEAVNFINKNVDKILAGSLNGKSIGIISANE
                     NDDYTKNIEDIINKSNGSIAFNIILKENITNPEKLKEMSTKLGTDVKNANDAVNYIID
                     TLKKEDASDILTYLQELDVIKFNFIGDTYLKYDSVVIAGGNDAKDSTKQFEKIEKFVV
                     SKLKSENKYLVEVQNTGVKTSYVELYSKNKVATIDNIDEGIGSISLAILLQQGNIVGN
                     FGRLDTATSLLPSIK"
     gene            40448..41140
                     /locus_tag="OE968_000279"
     CDS             40448..41140
                     /locus_tag="OE968_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HCP7217596.1"
                     /translation="MDSYISIIIPAYNEESRIKYTLESILDIKQINEIIVVDDGSIDN
                     TAKVVSELENEKIKFFKLDKNRGKGYALNYGIKLAMKNADIIGFLDGDLGSSAKEVEK
                     LIVPILNGEADVTIAKFPPAKRKGGLGFVKGLAKNSVFEMTGVELDATLSGQRIFKRE
                     VLEKFDEIPFGYGVEVGMTIDILKYGFKIKEVLVNMTHNETGRNLKGFIHRGKQYYHI
                     KKVLGQKKKEWR"
     gene            41148..41972
                     /locus_tag="OE968_000280"
     CDS             41148..41972
                     /locus_tag="OE968_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HCP7217597.1"
                     /translation="MKDYILYTILLLTGLFGTYAVIPLFKNLLINGNVLRPNYKKDMI
                     PVSMGIVFLPMIVINGIILAFFTTEFKDLAYIFMFMFGMISMFFAGILDDVIGNRDVS
                     GLKGHFKSLFKGSLTTGGFKALFGGFVGLIVSVAISKDIIDIIVNTLIIALSTNLMNL
                     LDLRPGRAIKAYLFIMVIIFLTLTGFVQVLPLLIVPNVLAYFNYDLKARAMMGDTGSN
                     VLGISIGMLISFGYPFNIRLGWLIFVVIMHIFTEKYSLTKIIEKNKLLNFIDKLGR"
     gene            41977..43044
                     /locus_tag="OE968_000281"
     CDS             41977..43044
                     /locus_tag="OE968_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3866 family protein"
                     /protein_id="HCP7217598.1"
                     /translation="MISKRVGIVESIVSQTETLDDIRVNINGEIQRAYNYPKISGTIN
                     IGDEVVLNTTAVELSLGTGGYHFVITNLNNIESTLTEGGHIMKLRYTPLQIKVDSVEE
                     QESIYHDKFANFKGLEGLSVVVGTLHSMLTPFAASFKRNNPNKKLVYIMTDGASLPIY
                     LSKNVDTLKEKKLIDSTITIGNAFGGDYECINIYTALITAKEILKADAVFVSMGPGIA
                     GTGTKYGFTGIEQGSILDAVKKLEGRAIAIPRISFADKRERHQGISHHSMTVFKEIVN
                     VNVDIPITIYDDEKLNFIKEQINLNGLDKKHNIIYIDNNKTKEDLDYFNLKVKSMGRN
                     YEQDEAFFKAASTAAYYLMEV"
     gene            43046..43582
                     /locus_tag="OE968_000282"
     CDS             43046..43582
                     /locus_tag="OE968_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HCP7217599.1"
                     /translation="MVLEEKTISSDRVYTGKVITLKVDTVEIPGQGYQKRELVEVGGA
                     VGIVAITDDNKVVLVKQFRKPIEKPIFEIPAGKLEKNESPKECAERELKEETGYSAKN
                     IKLIHKFFTSAGFSNEIMFVYLATGLTPGENNLDADEFLDVYEIELEEAYNMVLKNDV
                     EDAKTSIGLLLVKDMFKN"
     gene            43650..44255
                     /locus_tag="OE968_000283"
     CDS             43650..44255
                     /locus_tag="OE968_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein M"
                     /protein_id="HCP7217600.1"
                     /translation="MRRTYRKNDFRELNRQIIIIGLLFMMSIVVGSYINKILPGSSNN
                     ILNNINPAVEYYNLNISIKDTVIQNLKSDAIFMGSIALLSLFVVTIPAVLVAFVLKGM
                     SIGYTINSCILALKFKSIKMILIILFKNLIIIPCAIILALISLSYFKEMVYEFKKKNR
                     KNMQFLIKRYILNIIIIIALSLGLQLILNTASIGIIKFLAK"
     gene            44267..45181
                     /locus_tag="OE968_000284"
     CDS             44267..45181
                     /locus_tag="OE968_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HCP7217601.1"
                     /translation="MDIIEGYIDYIKDKKKLSENTVASYFMDIKKYMEYINQKSIKLV
                     DIVENDIISYLIKLEKDNVSIATIARMISSIKSFHDYLFLNHICTNNPAKDIKKPKIK
                     KENINILTEEEIERLLNFPKLTTPKLIRDKAIFEVLYGTGIKVSELVEMNIEDIDLDI
                     DYIYCNSCCKNQRVIPLCDITKLYLEKYLKEARPKMAVEGEKSLFVSSLGQRFTRQGL
                     WKVIKKYSNLANIDKNINPTMLRHSFAIHLLNEGANIAVVSKILGNVNLSSLQVYLNH
                     IDKNVRREIKEKHPRNDVDVELQKAEAK"
     gene            45223..46395
                     /locus_tag="OE968_000285"
     CDS             45223..46395
                     /locus_tag="OE968_000285"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HCP7217602.1"
                     /translation="MSRVIWIVIDSVGIGALPDAEKFGDSKDVSTLGNIFKEYPDIQI
                     PNMRNLGIGNIDGIDFFESIKEPIGCFGKCKEMSQGKDTTTGHWEMTGIIVDKPFKTF
                     EHGFSKEIIEEFEKKTGRKVVGNKPASGTVIIDEYGEHQIKTGDVIVYTSADSVFQIA
                     ANEEVIPLEELYNMCKIAREIMMGDNAVARVIARPFIGKKKGEFVRTSNRRDYSLDPF
                     EPTVLDNIKESGLDVLAVGKIEDIFNGKGITDAIHTKSNMDGVDETLNYMKQDNKGLI
                     YSNLVDFDSKYGHRRDPEGYKKALEEFDSRLPEIMANMREDDILIINADHGNDPTYKG
                     TDHTREYIPVMIYGNKIKKGFNLGVKDTFADIGATVADILNVKLPKHGSSFKEDLF"
     gene            46442..47254
                     /locus_tag="OE968_000286"
     CDS             46442..47254
                     /locus_tag="OE968_000286"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HCP7217603.1"
                     /translation="MFEKIAQSSKFINSKSDIKPKIGLILGSGLGDLANDIEDPVAIK
                     YSEIPNFPVSTVAGHAGQLVIGKLEGKEVIAMQGRFHYYEGYSQKEATFPVRVMKELG
                     VEILIVTNAAGGVNKEFKAGDLMLIRDHINFSGSNPLVGKNDDRFGARFPDMSDAYSS
                     KYVDVVKNCAKECNIDVKEGVYMFFSGPNYETPAEVRMAQILGADAVGMSTVPEVIVA
                     SHSNIGVIGISCITNMAAGILNQPLSHEEVIETTQKVKSEFMNLVKTTVKNL"
     gene            47458..48783
                     /locus_tag="OE968_000287"
     CDS             47458..48783
                     /locus_tag="OE968_000287"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HCP7217604.1"
                     /translation="MRMYDIIKKKRDNLELSKKEINYFIENYSKGDIPDYQASALLMS
                     IYLNKMNKQETVHLTEAMMNSGDMINLSEIDGIKVDKHSTGGVGDKTTIALIPLVASC
                     GAPVAKMSGRGLGHTGGTIDKLESIPGFSTEMEISKFIDSVNKSKIAVCGQSAKVAIA
                     DKKIYALRDVTATVDNISLISSSVMSKKLASGADAIVLDVKTGDGAFMKTLEESFELA
                     KSMVDIGTGMNRDTIGIVTDMDEPLGFAVGNSLEVIEAIETLKGNGPKDLVELCEVLG
                     AYMLVLSKVAHDFEDGVEKIRESIKSGTAIQKLKEFIENQGGNKDVVDDYSLFKKSKY
                     KYPVKSTKSGYISKIKAEDVGVSAMILGAGRETKDDILDLSAGIILEKKVGDYVNEGE
                     VLAYMYYNDEQKLSLAKGRFIDSYSIVDSKIEKNKLIYGIVTKEEIKKF"
     gene            48996..50075
                     /gene="mltG"
                     /locus_tag="OE968_000288"
     CDS             48996..50075
                     /gene="mltG"
                     /locus_tag="OE968_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HCP7217605.1"
                     /translation="MNFKENRLKIAVLIIVILIILAGIFVFIQIGPYDKNNKKDVIID
                     VPSGASVGKISDILYENKLIKNELLFKLLVKVSNKAPSIKSGTYLLNQSYSNNDIISL
                     LVSGKIYQDGIKVTIPEGATSKEIIAMLVSKNLGDKATFENLIKKPQEFYDKFPYLKE
                     DGITSLEGFLYPETYYFNSKKQSEEDILSEMLKVFDSKYTDKFKKKQKELNMTLQEVM
                     EMASIIEKEAVLDKDRPIIASVFYNRLKVGMPLQSDATIQYIFEERKKIVTYDDLKID
                     SPYNSYKNKGLPPTPISNPGIKSIEAALYPEKTDYLYFVAKIDGGNNYSTNYQDHLKY
                     VKEYKEARDKQSKDTKATNKENTKK"
     gene            50247..50921
                     /locus_tag="OE968_000289"
     CDS             50247..50921
                     /locus_tag="OE968_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HCP7217606.1"
                     /translation="MSNIVNDLVEDYIRVTLKEKEGFLKDLEIYAEENSVPIIHKEVS
                     DLLKVLLKVQKPKRILEVGCAIGYSSIFFATIIGKDADIITVERNEKMIEKAKENIKL
                     AGFDNNITILEGDAEEKLSQVQGEFDLIFIDAAKGQYKLFFDLVIDKLKDGGLLVSDN
                     ILYKGMVAHDDFVVRRKKTIVKRMRNYLDYICNCDYLSTSLVPIGDGVALSYKESKRG
                     DVDGIK"
     gene            50908..52155
                     /locus_tag="OE968_000290"
     CDS             50908..52155
                     /locus_tag="OE968_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HCP7217607.1"
                     /translation="MELNKVELLAPAGDLERLKIAITYGADAVYIGGEIFGMRSAAKN
                     FSKEDMAEGVAFAHERGKKVFVTVNIIPHNEDFLQLEDYLLELEEIGIDAVIIADPGV
                     LSVIKKVIPNMEIHLSTQANTTNYLSANFWYEHGIKRVVVARELSFDEISEIRAKTPL
                     DMDIEAFMHGAMCISYSGRCLISNYMTGRDANKGSCAQSCRWQYHLVEEKRPGEYFPI
                     YEDERGTFFFNSKDLCMIEYIPELIKSGITSLKIEGRMKTAYYVATVVRAYRMAIDEF
                     YRDPENWKFNPMWMEELKKGSHRHFTSGFYLNKPTTEDQNYQSASYVRNYDFIGIVRE
                     TEDEDGLIVVEQRNKMCVGDEIEVMGPYKETMFTKIEEMYNEEGEAIESAPHPRQIVK
                     LKLSVKVGKDYMLRKVIEEKVEE"
     gene            52227..53891
                     /locus_tag="OE968_000291"
     CDS             52227..53891
                     /locus_tag="OE968_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HCP7217608.1"
                     /translation="MSKKKTPFLKKVGKRSWCIFTIILIIYSVLIYRLVDIQVLKGDK
                     YKQSVESQSVEKVELNSGRGIIYDRNNKKLTDTSKSQVLIVEKEKLNNNYKILELIKK
                     ATKMNDLDIYKAVQEQLTRPIIQIQTKNIDKSMKKELEKNGIMVEEKTMRYAKDGLLS
                     HTIGYIKEDDKSGQSGIEKSMDSVLRNSNEKYISAFKAGDAGNEKSLNILKGSVKTVD
                     NKDKDRHLKTTIDYNIQKKLEQILNKEENPTAAIISEASTGEILAMCSRPNFDQNDIS
                     KSLKGKNGEFENRVIKATYPPGSVFKMVVLFSALENGVIDENYTYNCTGKTKVGNTNE
                     ILRCNKRDGHGFQNLRQAFSNSCNPAFLDIAMKLGKEKILKSAEKLHLFEKVDIGLDE
                     EKIREAPKNISIRNLAIGQENIEFTPLQINQMTQIIANNGTFKPLYLYKSLVDNNMNT
                     IKTYKSSKKEELISPYVCTQVKEYMKSVSRIGTAKDLKDIEGGCGVKTGTAQSSLNKK
                     AIDHGWITGFYPEERPKYVITVLVEGTQKGNKSATPIFKEICESIK"
     gene            complement(53988..54629)
                     /gene="sigK"
                     /locus_tag="OE968_000292"
     CDS             complement(53988..54629)
                     /gene="sigK"
                     /locus_tag="OE968_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018589741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigK"
                     /protein_id="HCP7217609.1"
                     /translation="MAALKSFEKPLTPEEEIEYLTKFKIENDKSAKDTLIERNMRLVA
                     YIAKKYNNSTEDQDDLISIGTIGLIKAIETYNIDKGTRLATYASRCIENEILMNIRSN
                     KKNKTQVSLQDPIGTDKEGNEISLLDILGTEANYVLDEVELKVQVGKLYEQLNKILTP
                     REREIVQLRYGLTPYGYKTQREIAQKLDISRSYVSRIEKKALKKLEKELVQES"
     gene            55196..55558
                     /locus_tag="OE968_000293"
     CDS             55196..55558
                     /locus_tag="OE968_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7217610.1"
                     /translation="MKIRKSGFISIECIISIAILYVAVYLVSTSLYNCYSFISRNISD
                     REMLSTAKKYIEDEKYRIQNSKYELIEDKIEKNYINGYEINSRIEQILDYYQCYEINI
                     EIKNEFKKLRFNSYVTRK"
     gene            55542..56249
                     /locus_tag="OE968_000294"
     CDS             55542..56249
                     /locus_tag="OE968_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7217611.1"
                     /translation="MLLENKGSILIITLIIFSIISTVCIMCIGLIYTHNNMFELGYKD
                     IQLKEISLSGIEISVSNVLSCVEEAIDISNNEDEFREYFLGNNMIECIKKIKDTSYSS
                     LEELSLKVENNTIYDRGDFFEFDIESNVREKEFLKAIKVRVKIKNPWIGIDIEDYMDK
                     SNNNKIDDKTFNNYKASENNEIINQFKNESENIRNQEVVEFTEEDEEELKQNIIENIK
                     KNFDEKNLVQVYKYRGV"
     gene            56269..56688
                     /locus_tag="OE968_000295"
     CDS             56269..56688
                     /locus_tag="OE968_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7217612.1"
                     /translation="MTVIELIVSISIILLIVTLSFPKDNLENHKINLFARQLCSDIRY
                     VRRINMFSNYNTYIYYINQGKHEGYVLRKDGKNIKSIMLPKNAKIARSIEIIKFKSDG
                     SPQKASTIEVYNNRLRKTITITPVSGRVLLKEGKYET"
     gene            56678..57202
                     /locus_tag="OE968_000296"
     CDS             56678..57202
                     /locus_tag="OE968_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7217613.1"
                     /translation="MKHKYGYLLLESVVSLSSMVIIILVLYSIFLSTINLKLKVEDKI
                     ELQQQSLEIIKSMEGIISNSMGIMNVSNYEETFKKTTSIKCRYLDENNNEEGISNKEI
                     ILNERRNKLFVNSLNGESSQAGGYEIGDYVDEMYVSITNNGQYVNIKLKLSKCSQKYE
                     TDFKIKVWNFSESI"
     gene            57514..58071
                     /gene="efp"
                     /locus_tag="OE968_000297"
     CDS             57514..58071
                     /gene="efp"
                     /locus_tag="OE968_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HCP7217614.1"
                     /translation="MVSAGDFRKGVTFEKDGQPCLVVDFQHVKPGKGAAFVRTKYKNL
                     KTGAIREESFNPSEKFPKAVIDTRQMQYLYNDGELYYFMDQENFEQIPLNYEQVEDAI
                     KFLKENEVATIRFYQGQPFQVEAPNFAELEVTDTEPGIKGDTASNVTKAATVETGAVV
                     QVPLFINTGDKVKIDTRTGEYLSRV"
     gene            58163..58618
                     /locus_tag="OE968_000298"
     CDS             58163..58618
                     /locus_tag="OE968_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HCP7217615.1"
                     /translation="MKHLYEEVAYLKGLAEGLEISAESKEGKMIHKIVDALEVFADAI
                     VTLDEEQEELQDFVESIDEDLADLEEDIADMEEDLYEEDDDEDDEDFSYIEMECPNCG
                     ELVEIDEDLLYDDEVDVVCPDCKAVILSSEDDCDDDCTCGGCSSCDDRE"
     gene            58781..59491
                     /locus_tag="OE968_000299"
     CDS             58781..59491
                     /locus_tag="OE968_000299"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HCP7217616.1"
                     /translation="MKISKKLLDNIQRFENVINYKFKNKEYILEALTHSSYSNENKKY
                     NFNERLEFLGDSVLGIVISDYLFNEEANLPEGELTKLRANIVCEDSLSEVANDINLGI
                     HMLLGRGEEATGGRHRTSILADAFEAVIAAIYLDGGFESARQFILHHMENIIYDSRKG
                     NIFRDYKTHLQEVLQGNGENNIWYRLIEEKGPDHNKRFVMEVGINDDVLGIGEGKSKK
                     EAEQLAAKIALKKKLWEK"
     gene            59545..60615
                     /locus_tag="OE968_000300"
     CDS             59545..60615
                     /locus_tag="OE968_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HCP7217617.1"
                     /translation="MKKRIIPIFVPHKGCPHDCIFCNQKKITGVSTDVTSEDARNIIE
                     ECLETIDKDADVEIAFFGGSFTAIDIDIQKSLLSVAKEYVEKGLVKDIRMSTRPDCID
                     EDILSMLKEYKTSIIELGVQSLDEKVLLDSIRGHQSEIVYKSSKMIKNSGIKLGLQMM
                     IGLPADTEEKCIFTAKKFVELKPDCVRVYPTLVVKDTGLEKLMEQNKYNPFTLEESVN
                     IVKKVLVLFYVNNINVIRVGLQATDDIQIGKAVLAGPYHPAFRELVEADMIKDYLEFV
                     ILQNKNIKQMLVKSNKKNISKIIGNKKTNVKYMEEKFGVLLKTQESDLDINQLEIVLD
                     GKSLISANMRDIHRKLYDIYDL"
     gene            60643..64197
                     /gene="smc"
                     /locus_tag="OE968_000301"
     CDS             60643..64197
                     /gene="smc"
                     /locus_tag="OE968_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HCP7217618.1"
                     /translation="MYLKRLELKGFKSFPVKTDIIFKEGITAIVGPNGSGKSNISDAV
                     RWVLGEQSIKSLRGDKLEDVIFAGTDTKKPMNYCEVALTIDNSENQLELDFTEVTIRR
                     RAYRNGESEFFLNNKSCRLKDIKEVFLDTGIGKDGYSIIEQGKVDEILSNNPLSRRKV
                     FDEACGISKYRYKKQEAERNLSNTKENLERIDDVYIEIENQLKPLFNQQTKAKKYLEI
                     SEKLKTLEVNSFIREIEGIEKELSEVNEHRKVIEKELNEKEEQKNVVEKKQEDINKEV
                     EVLQDVIEKSVDYINSIKGVISKKESQINLIKERIRNFTNEISRKNLEINDIKEKLNE
                     NKQYIKELESNKLSGSEELSTLQENIKVLEASKDKQKIKLESLNNEIELLKESIIDIL
                     NKKQEFSNKLSTLNANKENMNIRDENINSEITELNKNIEIKSSELDTINKEFNMQNEN
                     LKNVNNRHKELSTNLQDSISEHNKLEDEIQKSKYNLNGYNSKLNVYIDMENHYEGFNR
                     GVKEVLKNKNLKGVHGALGQIINVPEKYEKSIEAALGAYMQNIITDNEFSAKSAINYL
                     KQNNLGRVTFLPLNIIKSNKISLGNLKANTKFIGIASDLITFDEKYRNIIENILGRTI
                     LINNIDEGIKFAKETGHRFKIVTLDGEILNPGGSLTGGSLKTNGNILSRKRYINEYTE
                     KISNIKNEISHLELKRESLDKDVKNIKNEIDSHESKIKDLEKSIIIKSTSIKNVESEI
                     ESLKGSITKLENEKNDLNSNLNYTLEKSDDVRKDMEELDDLYNKNKEKIDALNEEIKR
                     YNDLYDKEKSEFDELNLSLVKKTEVYNSIVRDIKRISGENCELEEKNKQLEESLNYEE
                     HEIIKLQDSILTEEKEKENLTKQLGDSNRNLETRKIAKDDLKNSFDEINKELKTIDRQ
                     HIELKESLFKVGGRLERLKTSQDTYINKLFEQYDMTLVQALEIKDEDLDIDRKFLESL
                     KREIRSLGNINIDSIKEYEEIKERYDFYSEQKQDLEESMEEIEKLIHTLEENMKSEFE
                     IKFEEISKNFKYVYKRLFGGGCGELTILDKENLLESDILITAQPPGKKMKNLNLLSGG
                     EKALTAISILFAILITKPTPFCILDEIEAPLDDANIFRFGEFLKDLSKETQFISVTHR
                     RGTMEAADYIYGVTMQEKAISKVISLKLKEAQEITDII"
     gene            64224..65504
                     /gene="ftsY"
                     /locus_tag="OE968_000302"
     CDS             64224..65504
                     /gene="ftsY"
                     /locus_tag="OE968_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HCP7217619.1"
                     /translation="MLKKLFGFGKDKEKEIEKKDAEEEIEVEDSVDNLENLEETIFSG
                     LEEEVIDKVEDVEEKNEESVNNEGTEEIENFEKIEVEMDSNGKEVENISNNDSQEEII
                     EELENYDEIESKEIEDKEDKKVNLFERLKQGLTKAKQGITDRIDEVLKSYTKIDEELL
                     EDLEEILITADVGVNTTMDIIERLRDKIKQKGITEPIKVREELKSIVEDILTNENSTL
                     DIEPVPCIILMVGVNGVGKTTTIGKLANRYKKDGKKVLLAAADTFRAAATEQLEIWAN
                     RTNVDIIKHQEGADPGAVVFDAIKAAKARKTDVLICDTAGRLHNKANLMNELGKVFKI
                     VDREFPEAKREVLLVVDATTGQNAVVQAKTFKEVADITGIVLTKLDGTAKGGVVLAVK
                     SEVDVPVKLIGVGESVEDLQDFNAKSFSDALFGN"
     gene            65607..65975
                     /locus_tag="OE968_000303"
     CDS             65607..65975
                     /locus_tag="OE968_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HCP7217620.1"
                     /translation="MNIEKMVEIGLLFEQYKELLTDKQKEIVALYYEEDYSLGEISEN
                     LNVSRQGVYDTLKRSEKILRDYEEKLHLVSKIQEQEKNIKIIKDKIIDIKEDLLHNRD
                     CANLIPKLENIEDVCREMIK"
     gene            65972..67324
                     /gene="ffh"
                     /locus_tag="OE968_000304"
     CDS             65972..67324
                     /gene="ffh"
                     /locus_tag="OE968_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HCP7217621.1"
                     /translation="MIFEGLSDKLQGAFSKLKSKGKLTEVDVKNAMREVKLALLEADV
                     NFKVVKDFIKKVQERCVGQEVMQSLTPAQHVIKIVNEELTSLMGDVQSKVMISSKPPT
                     ILMMVGLQGAGKTTTAGKLGGYFKKQGKKPLLVACDIYRPAAIKQLQVVGEKLDIPVF
                     NMGDKENPVNIAKAGLSHAIKNANDLVIIDTAGRLHIDEVLMDELKSIKSEVKPHEIL
                     LVVDSMTGQDAVNVAESFNEALGVDGVVLTKLDGDTRGGAALSIRAVTQKPIKFMGMG
                     EKLDDIEPFHPDRMASRILGMGDVLSLIEKAQENIDLEKAKELEQKIKKQELDFEDFL
                     QQMEQIQNMGPLDKILGMIPGMGNVKDQLGDVDLNGKEMKRTKAIIQSMTTYERRNPG
                     VLNASRKKRIAKGSGTSVQDVNRLIKQLNEMKKMMKMFAGSQKSMKKRGGLGGLPFFK
                     "
     gene            67362..67634
                     /gene="rpsP"
                     /locus_tag="OE968_000305"
     CDS             67362..67634
                     /gene="rpsP"
                     /locus_tag="OE968_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HCP7217622.1"
                     /translation="MAVKIRLKRMGANKKPFYRIVVADSRAPRDGKFIEEIGYYNPIS
                     EPKQVRINDEKAIKWLATGAQPTEVVKKLLVKNGVIEKFEASKQAK"
     gene            67699..67926
                     /locus_tag="OE968_000306"
     CDS             67699..67926
                     /locus_tag="OE968_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HCP7217623.1"
                     /translation="MKELVVDIAKALVDNPDSVVVEEFEDNDGIVLKLTVAQEDMGKV
                     IGKQGRIAKAIRTVVRSVANRENIKVSLEIV"
     gene            68034..68549
                     /gene="rimM"
                     /locus_tag="OE968_000307"
     CDS             68034..68549
                     /gene="rimM"
                     /locus_tag="OE968_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA processing protein RimM"
                     /protein_id="HCP7217624.1"
                     /translation="MKEKLTHFKVGQIVNTQGLKGEVRVYPLTDDIERFDELKDFYLG
                     KDLNNKLAVEKVRYKGSMVIMKIKGIDSIEKAEKLKNKFMYVSREDSRELEEGEFFIA
                     DMIGMEVLTVDGKYVGILEDVLQYSANDVYVVKGEEDKEFMIPAIKKFVPTIDIDERK
                     MIIDPIKGMID"
     gene            68558..69253
                     /gene="trmD"
                     /locus_tag="OE968_000308"
     CDS             68558..69253
                     /gene="trmD"
                     /locus_tag="OE968_000308"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HCP7217625.1"
                     /translation="MRFHIMTLFPEIFNSYMDESIMKRAVEKGIIEVHIYNIRDFSNN
                     KHKKVDDYPFGGGAGMVMTPQPIYDTYKHIITTHNINNPSVIYLTPKGKVYNQSMAKQ
                     MSLKEDIILLCGHYEGIDERIIDLIVTDEISIGDYVLTGGELPALIMIDSISRLIPGV
                     LNQEESFEEESFKDNLLEYPHYTRPRDFEGLKVPEVLLSGNHKKIDEWRREESIRITK
                     ERRFDLYKKSNEK"
     gene            69438..69788
                     /gene="rplS"
                     /locus_tag="OE968_000309"
     CDS             69438..69788
                     /gene="rplS"
                     /locus_tag="OE968_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HCP7217626.1"
                     /translation="MNEMLRAIEQEQLKNEVPNFGPGDTVKVHVRIIEGKRERIQVFE
                     GVVLKRQGGGARETFTVRKMSFNVGVERTFPVHSPKIEKIEVTRKGKVRRAKLNYLRG
                     RVGKAAKIKEARNK"
     gene            70109..71005
                     /gene="ylqF"
                     /locus_tag="OE968_000310"
     CDS             70109..71005
                     /gene="ylqF"
                     /locus_tag="OE968_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HCP7217627.1"
                     /translation="MSNEYEEYLMDDNLHINWYPGHMKKTKELVKNNLKLIDVVIELL
                     DARIPFSSKNPDIDRLVGDKPRVVVLNKSDMADRDKLNQWIEYYKKINIKAIPVDTIK
                     GVGINKIIEECKNVTREKMSSLKDKGRKERAIRIMIVGVPNVGKSSLINKLTGRKSTQ
                     TGDKPGVTKGKQWVRLKGNLELLDTPGILWPKFEDQEVALNLAFSRAIKDEILDTETL
                     ALRLIEKLMKIEPEKLKARYKLDCLGETPIETMDMIGHKRGFITGKKELDYTRIATTV
                     LNEFRDGKIGNITLEVPENVKR"
     gene            71394..72686
                     /gene="brnQ"
                     /locus_tag="OE968_000311"
     CDS             71394..72686
                     /gene="brnQ"
                     /locus_tag="OE968_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HCP7217628.1"
                     /translation="MGKTKDVIVFGFALFAMFFGAGNLIFPPYLGIITGPEWLIAFLG
                     FTFADAGLALLAVMATAKFDGNVVEMFKRCGMKLGILIGCADILCIGPFLAIPRTGAT
                     TYEMGIMPLFGTSIPVLLFCILFFALSYVLTIRPSKVVDIVGQFLTPALLIALAFIII
                     KGIISPLGDIVDKPMIPNVFAEGIGQGYQTMDAFAAIALASVLIVSLNDKGYSTISDK
                     LKMIGKAGVLACGGLALVYGGLCFLGATVSTMYGTDAVQSQVIVNITEGLLGNVGKAI
                     LAVVVSLACLTTSIGLTSATGQYFSRLTKGKLSYEKIVLAVSVFSAVVASFGVGTIIK
                     IASPILSIVYPPSIVLIILAFFNEKIKNDNVYKGAVYMSLLVSILTVISSYGVAVPVV
                     NSLPLNSLGFNWVVPVIIAGIIGNFIPSKSQSNTLGTN"
BASE COUNT        29837 a         7246 c        13553 g        22171 t
ORIGIN      
        1 tattatttat aaaaaaatct aaggaggaaa taataatgaa aatattagta ttaaactgtg
       61 ggagttcttc attaaaatat caattaatag atatgaataa tgaagaagtt ttatgtatag
      121 gattggttga aagaatagga atagaaggtt ctatattaaa acatgaaaaa gcaggtagag
      181 atgataaata cgttgttgaa caaccaatga aggaccacaa agatgcaata gcattagttt
      241 tagaagctgt tgctcatcca gaatttggtg cagttaaaga aatgaaagaa atagatgcag
      301 taggacatag agttgtacat gctggagaaa aatttgcaac ttcagtagta ataactccag
      361 aagtagaaga agctttaaaa gaatgtatag atttagctcc acttcataat ccagcaaaca
      421 taatgggaat agatgcttgt aaagctatac ttccagatgt accaatggta ggtgtatttg
      481 atactgcttt ccatcaaaca atgcctaaat cttcatactt atatggttta cctcatgagc
      541 tatatactaa atatggggta agaagatatg gattccacgg aacttctcat aattatgtat
      601 ctcagagagc agcagagata ttaggaaaag atataaaaga tttaaaaata gtaacttgtc
      661 acttaggaaa tggtgcttct atagctgctg ttgatggtgg aaaatgtgta gatacatcta
      721 tgggattcac tccattagaa ggattaataa tgggaactag atgtggagat atagacccag
      781 ctatattacc attcttaatg agaaaagaag gtttagatgc tgatggattg gataaattaa
      841 tgaataaaga atctggagta tatggaatga ctggaatttc tagtgacttc agagatatag
      901 aagatgcagc taaaaatgga gacgaaagag ctcaagctac attagaagcg tatgttaaaa
      961 aagtacaaaa atatataggc gcttatgctg ctgaaatgaa tggattggat gttgtagtat
     1021 ttactgcagg cgttggtgaa aatggaaagg ctataagagc agatattgct tctaacatgg
     1081 agtttttagg aatgaaatta gataaagaag ctaatgatgt tagaggaaaa gaaacagtaa
     1141 tatctactgc tgattctaaa gtaaaaatgc ttttaatacc aactaatgaa gaattaatga
     1201 tagctagaga tacattaaga ttggtaaaat aattaaatta aacctatgcc tatcaagtaa
     1261 aaatacttga caaacaaatg ctagatttgt ataataaatt tggtgatatg ttgaggtgaa
     1321 cttaatgaaa gttagcatag aaaaaataaa tagaaaagaa actgacaaaa tagacttgaa
     1381 tttttgtgaa aaaattgata ctattagtta ttgtgatgag atttacaaat tagtatcacc
     1441 tgtaaattta aaagggaaag tgtcaaagac taataaaggt ttgtatctag atatagatgt
     1501 caattttaca attgttgaca attgttcaag atgtcttaaa gaagtagaaa taccactaga
     1561 gtattctata caaggttttt tagtaaaaga agaagattat gatgaagatg agtttgagga
     1621 atttgatcct tttatattcg atggtgaaga aatcgacctt attgatataa tagaacagac
     1681 attagatttt aatgtacctc ataaagttct ttgtagtgaa aactgtaaag gtctttgtca
     1741 agtatgcggg gcaaacttaa atgaagaaga gtgttcttgc agtgaaatta caaacgatga
     1801 ggaatacata gatcctcgtt ttgctaaatt aaaagattta tttaattaaa ttttgactaa
     1861 ggaggtggcg taaatggcag taccaaagcg taaaacgtct aaatcaaaca caaaaatgag
     1921 aagagcagct aactcaaaga tggaagcaac aggatttgta agttgcccac aatgtcatga
     1981 gccaaaatta ccacatagag tgtgtccaga ctgtggatat tataaaggta aagaagttgt
     2041 gtctaagtaa tagcttctaa aaagcatgta gagtatactc tacatgtttt ttttgtacat
     2101 ataaaaaaat aagatgattt actagagaaa ataagtggat tttatgcata ttaaaaaata
     2161 gaaaaataat aatataagta ttgaaaattt ttgtgtgtta ctatatacta ctattagtag
     2221 ctggtactaa ttacagctat aaaatttgga gggaacatga aaaagaaaag taaagcccaa
     2281 agacaaaaag agcttataga tatgctaaag acagatcctt tttatactga tgaagaatta
     2341 tcaagtctgt ttgatgtaag tatacagacc ataagattag atagaatgag tctaaacata
     2401 ccagagctaa gagaaagagt caaatcaata gcagaaactc agagttcaaa agtaaagact
     2461 ttaggagtaa aggaaattac aggagaaatc attgatttat ctgtagggcg attaggtata
     2521 tctatgttag aagttacaca ggacatgatt tactctaaga ctaatacttt aaaagatacg
     2581 tatatttttt ctctagcaga ttcattggca atggctataa tagatgcacc taaggttatt
     2641 atgagagttg caaatgtaaa aagttttaag ttgatagaac aacaagatag acttatagca
     2701 aaagcagaag tgtatagaaa tatagataaa aagcattatg taaaagttgt tatcaacaat
     2761 aaagcccaag agcaaatatt tagaggaaag tttatctttg aagaattaga ttaggaggga
     2821 aattatgaaa atagtaattg atggaatggg tggagataat gcacctaaat ctaatgtaga
     2881 aggcgcagta aatgctataa aagaatatca ggttgattta ataatcacag gagataaaga
     2941 tttacttgaa aaggaatttt caaattatga atttgataga aataaattag agatagttca
     3001 tactactgag attatagaaa acgaagataa accagtaaag gctataagaa gtaaaaaaga
     3061 ttcatctatg gtagtagcat taaatcttgt aaaagaagga aaggcagatg ctataatatc
     3121 agctggaaat acaggagcct tacttgctgg tggattattt gttgttggta gaataaaagg
     3181 aatcgataga ccttgcttat gttcagcaat accaaatgta aagcgaggaa tgacacttat
     3241 agcagactgt ggcgcaaatg cagattgtaa acctaagaat ctagttgaat ttgcagctat
     3301 gagtaatatt tattcaagaa aagttttagg tcttgaaaat cctaaggtag cattagcaaa
     3361 tgttggacta gaagaaggca aaggcaatga tttagtcaaa aggtcatatg aagaaattaa
     3421 aaaattagat ttaaatttta tagggaatgt agaagctaga gaagttataa atgcatacac
     3481 agatataatc atatgtgatg gatttacagg taatatatta cttaaatctg ctgaaggtgt
     3541 agcactttca gttatgagtc ttataaagga aacttttatg gccagtacaa aaagtaaaat
     3601 aggagcatta cttataaagg atgatttaag aaaattaaaa agttttatag attattctga
     3661 gtatggggga gctccacttt taggtctaaa tggaggagtt ataaaagctc atggtagttc
     3721 tgatgctaaa gctataaaaa atgctataaa tcaaggaata aaattttcaa agggaaaagt
     3781 cgttgaagat attaaccaat ttataagcaa atacaatgaa gaaaataaaa ataacgaaga
     3841 tgaataaact cgttttggag gtttaatata taatgaatac aaaggctgga atattaggag
     3901 taggaagtta tctacctgag caatcatatg ataattttca cttcgaaaaa ataatggata
     3961 catcagatga gtggataagt actagaactg gtattaagga aagaagattt gccaaagagt
     4021 ctgaagcaac ttctgactta gcatctaaag ctgccttaaa agctatagaa tgtgcaaagt
     4081 taaacgtaga ggatatagag ctgattatat tagctacaat tactcctgat atgtctttgc
     4141 cttcaactgc atgtatagta caagatgcaa taggagcagt aaatgctact gcatttgata
     4201 tatcagcagc ttgttctgga tttgtatatg gagtaactat tgcaaagcaa tttgtggaaa
     4261 caggttgcta taaaaatgtg cttgtaatag gagcagaaac ttgttctaag tttttaaatt
     4321 atgatgatag aacaacagca gtattgtttg gagatggagc tggagcagct gttattggcc
     4381 ctgtaaatga gggtggaata ctgtctacac atatgggctc tgatggtaaa ggaaaagatt
     4441 gtttaaaagt acctgctgga ggttcaagac ttaaggcaag taaagagact gtagaagcta
     4501 atctacatac aatagaaatg gcaggtagtg atgtgtttaa atttgcagtt agaaagatgg
     4561 cagaaacttc tttaagagct cttgaaaaag caaatctaaa tacaactgat atagactact
     4621 tagtgccaca tcaagctaat ataagaatca tacaagcttc ttctaagaga ttagagcttg
     4681 atatgaaaaa agtttatgta aatatagaca aatatggaaa tatgtctgct gcatctatac
     4741 cagtagcatt agatgaagct tatagagaag gtaaaattaa aaagggtgat aatgtagttt
     4801 tagttggctt tggtggaggt ctaacttggg gggcttcagt tgtcaagtgg actttatagt
     4861 ataaaatatc taaaatgatt taattaacaa aattaaactt atacacaaaa taaagttgat
     4921 taataataaa aagtttactt ttatgatttc aagtgaagga gaattgtatg aataaaattt
     4981 gcaaaatatt aaatataaaa tacccagtta tccaaggggg aatggcatgg gtagctactg
     5041 catcattagc aagtgctgta tctaatgcag gaggacttgg cataatagca gcaggaaacg
     5101 caccaaaaga agctataaag aaagaaattg ttgagtgtaa aaaattaaca gataaacctt
     5161 ttggagtaaa tgtaatgctt atgtcgccat ttgttgatga tataattgat ttgattatag
     5221 aagaaaaagt tcaagttatt actactggtg ctggaaatcc tgcaaagtat atggatagat
     5281 taaaggaagc tggaacaaag gttattcctg tagtacctac aatagctttg gcacaaagaa
     5341 tggaaaagct aggagctaca gcagtaatag cagaaggtac tgaaggtgga ggacatatag
     5401 gagaacttac tactatggtc ttagttccac aagttgctga tgctgtaaac atacctgtaa
     5461 tagctgctgg aggaattgta gatggtagag gaattgcagc atcatttgca ttaggtgcca
     5521 gtgcagttca agtaggaact agatttattt gcagtgaaga gtgttctgtc cattcaaact
     5581 ataaaaactt agtactaaaa gcaaaagata gagatgcaat tgtaacagga agaagtactg
     5641 gtcatccagt aagaacatta aaaaataaac tatcaaaaga atttttaaag atggaacaaa
     5701 atggagctac tcctgaagaa ctggataaaa aaggtacagg agctttaaga tttgcaacag
     5761 tagatggaga catagaaaaa ggttcattta tggcaggtca aagtgctgct atggtaaaag
     5821 aaataacacc ttgtaaggaa attatagagg ctatggtaaa tcaagcaaga gagattatgc
     5881 cagcaataga actgtaaatc aggaggagca agatgggaaa agttgcacta gtattccctg
     5941 gtcaaggagc tcaatatgta ggtatggcca aggatttata tgaaaataat actgttgcta
     6001 aaagtgtaat agatgaggct agtgatgcct taaatatgga tttaaaaaac cttatgttta
     6061 atggaaatga agaagaactt tctaaaactg aaaacactca acctgctatg gttacacata
     6121 gtgtagctgt attaaaagca gtacaagccc aagtagattt aaaatatagt gcatgtttag
     6181 gtttatcttt aggagagtat agtgcattgg ttgcagcaga tgcaattgac tttaaagatg
     6241 ctgtatgctt ggtcaaaaaa agaggtaagt ttatgcagga tacagttcca acaggtgttg
     6301 gagctatggc agcaatttta ggtctagata gaagtatatt agaaaatgta gttaaagata
     6361 tacaaggagg tattgtggaa gtagcaaatt ataattctcc tggtcaaata gttatatctg
     6421 gtgaaaatga aaagatagaa gaagcaatgg tgaaatgcaa agaagcagga gcaaaaagag
     6481 ctgttaaatt aaatgtaagt ggaccttttc actcatcaat gctaagagaa gctggtgtaa
     6541 aattggccag tgaattagaa aaagttaaca taactaaacc taaagttgat gtggtggcaa
     6601 atgtaaatgc agattactat aaaaacgaag gtaaagacct gcttataaaa caagtaagtt
     6661 catctgttct ttgggaagat tctatagaaa gacttttaaa tgatggatat gatactttta
     6721 tagaaatggg acctggaaaa actttaaaag catttattaa gaaaatagct tccaataaaa
     6781 aagcaaatgt caatatttat aatatagatg gtatagattc tcttaatgaa tttgtacaaa
     6841 attatagaaa tggagagata taatgataaa tcttacagga caagtagcag ttgttactgg
     6901 tggctctagg ggtataggaa aagaaatagc aaaaaaacta gcatcttttg gagctgatgt
     6961 agtaatcaat tatacttcta aagaagatga agcactaaaa actaaaaatg aaatagaaag
     7021 tatgggggta aagtgtacct ctataaaatg tgatgtgtct aaatttgatg aagtgaatca
     7081 aatgatagat tctgttgtaa gcgaatttgg aaaaattgat atattggtta ataatgcagg
     7141 cataactaaa gatggtctgc ttatgagaat gaaagaagaa gattttgata gagttataga
     7201 tataaactta aaaggtgtct ttaattgtac aaaagcagtt actaaaccta tgatgaaaaa
     7261 gaagtatgga agaataataa atatgacttc agtagttgga attatgggta atgcagggca
     7321 aactaattat tgtgcatcaa aagcaggtgt aattggattt acaaaagctt ctgcaagaga
     7381 gttagcatca agaaacataa atataaatgc agtagcacct ggatttatag aaacagatat
     7441 gactaaagta ctaagtgatg atgtaaaaga atcaacacta gcaaacatac caaagaaatc
     7501 ttatggtaaa ccagaagatg tagccaatgc cgtagcattt ttagttagtg acatgtcaag
     7561 ttatataaca ggacaagtaa taaatgtaga tggtggaatg gtaatgcaat aataatttaa
     7621 aaagtagaga aatctattaa aataaaaaat tttaggaggt acacaatgtt taataaagtt
     7681 gtagaaataa taatagagca attaggagta gaagataaag aaataactat ggaaacatca
     7741 ttaatgaagg atttagaagc agattcatta gatgcagtag aaataataat ggcacttgaa
     7801 gatgaatttg gtatagaaat accagataca gaagcagaaa acttcaaatc tataggagat
     7861 atagttaagt atatagaagc taataaatag tcgagcttta aaaaagtgga ggtatccgat
     7921 gaataaaaga gtagtaataa caggacttgg atgtgttacg ccgttgggaa caggaaaaga
     7981 agagttctgg agtaatataa aatctggagt atctggtata gataaaataa ctaattttga
     8041 tgctagcaca tatcaaactc agatagcagg agaagttaag aattttcatc cagaagaata
     8101 tataagtaaa aaagaattga agagattaga taaatttgct caatttgcaa tagtatctgc
     8161 taaattagca gttgaagatg caaatcttga tttagataaa gttgatagag aacgttttgg
     8221 tgttataata ggttctggaa taggtggagt tgaagctata gaaactcaac ataaaattct
     8281 tttggaaaaa ggaaataaaa gagtaagttc actttttgta cctatgatga taggaaatat
     8341 ggcagctggt caagtttcaa tatttttagg agcaaaaggg cctaacacta atgtatgtac
     8401 agcttgtgca tcaggaactc attcaatagg tgatgctttt aaggtaattc aaagaggtga
     8461 tgcagacatc atggtagcag ggggttctga agctgctgta acaggtcttg cttttgctgg
     8521 attctgtaac atgaaggcta tgtcaactag aaatgatgac cctaaaactg catcaagacc
     8581 atttgataaa gacagagatg gttttgtaat gggagaagga gcaggtattg ttatcttaga
     8641 agacttagaa catgctttag caagaggcgc taaaatatat gcagaagtag ttggatatgg
     8701 tttaactgct gatgcatacc atatgacaac tccagctgaa aatggagagg gagcagctag
     8761 gtctatgaat atggctttga aagatggaaa tgttccatta gaagaagtag attatataaa
     8821 tgctcatgga acttcaactt attacaatga tttatatgaa actatggcta taaaaactgt
     8881 atttggagaa aaggcatatg acttatgtgt gtcatcaaca aaatctatga ctggtcactt
     8941 attaggagca tcaggtgcta tagaggctgt tgtttgtgct atgagtatag aagatagttt
     9001 tgtgcctcca actataaaca tacaagaagt tggtgaagat ttggatttag attatgttcc
     9061 aaatcaaggt aaagaaaaaa atattagata tgcactatca aattctttag gatttggtgg
     9121 gcataatgct acaatagtac taaaaaaata tgtataaata aatattaaat ataaaactaa
     9181 aaaacaagca cttgttttaa ctgtataaat ttatattagc ttaaatttaa agtctcctaa
     9241 attattttag gagacttttt tattaagatt taagtctagc atatgttgta aatcattttg
     9301 atatattgta ttattaatta ttaagaggtt atttatatat gtaagttttc attctacaat
     9361 atacaaaagg aggactaaaa ttttgaattt tagactacca aagaaaaggt tacccaaaaa
     9421 gataattttt atatgtataa tacttattag tattattttg tttataaagc atgaccaaaa
     9481 tggattgaaa gaaagagaaa ttataaataa gggaaaatat atgtctgaaa gccttgtggc
     9541 agataaggag tatgatgaag caaaaaaagt ggttaagact tctttcgaat ctattccaga
     9601 aaaaaaatac aataaagtat ataatgaagt ttgggatatg ttaaagacta tttcatatgt
     9661 tccagatgga acgaagatag tcattgattc tttagaaaag atgagagaat cagatgtgaa
     9721 attatctgat gaatgtagat ttaatataga aaaaagatta gcatcagtgt atataatgga
     9781 taataattat tctaaggcag tagatttaac tgtaaagtct ataaagttgg ctgagaaatt
     9841 ggggaataat tatgaaaaag caagactaga tgttgatttg gcgagcatat ttttaaagat
     9901 aggtggctat gaaacaggag agaaattaat aaaggattct tttaaaatag atattgatga
     9961 aggtgaaaaa aatggaatgg ttagattata tgctattata aatctagcag aaatatatgt
    10021 agaagagggc gaatatgata aagctattga aataagtagc aggataaaag attataaaaa
    10081 gtttgtaaat acggataatt acaatgattt tgatataatg gcctctataa tgcagtcaaa
    10141 tgcgtatgtg ggcaaaaata atatacaaaa ggcaaagact tttttagaaa aagctgatta
    10201 tcttataaaa tcagatagaa cagtttatat attagataaa gatatgtact attatatggc
    10261 aatgggaaac ttagaatata aaagcgaaaa ttataattct gcaatagata attataaaaa
    10321 aagtttagag atatctacta aaagaaagtt aacccaggag aaaataaaaa atttaaataa
    10381 gatattaaat atatatgaaa aacaaggaaa tatagaatct ttaaatgagt atcaaaagat
    10441 gttaataaat gaatataaag agaacaaaag tataagagat tcagagacta gtttctatat
    10501 aattgataaa gtatcaaacg aaagtaagct atttgaaaaa actaaaaaag aaataaaata
    10561 ttataaaata ttatttacag taattttaat tgctatatta gggtctactt ttttatacaa
    10621 ccgattgaag tattttaaag cacaaaattt acatgatggt cttacaaatg tttataatag
    10681 aaaaagtttt gatattatgt atgaaaagta cagagagaaa gatgataatt ttgcacttgt
    10741 gatgatagat attgataatt tcaagctcat aaatgataat tatggacata aatttggtga
    10801 cactgttata aagggaataa caaataccat ttgtgttatg ttagaacaag atgataaagt
    10861 ctttaggtac ggaggagaag aattttctgt attaataaga aataaatctg gtgatgaagt
    10921 agcagatata attgacagta taagggttgc aattgcaaat aaaaagtgga atgatgatgt
    10981 gactgtgact ataagtgcag gtgtagctca tgtttcagat agcaaagatg tactagaaga
    11041 agctgataaa aatttatata aagcaaaaca acttggtaga aataaagtag tatataagta
    11101 attatatact atataaataa gaggtataaa tatgaaacaa tcaatagcta tagtaactga
    11161 taaaataact aaactatcat ctttcttaga agaaaatata cgtttggttt taggtaatta
    11221 tattgatata aaccactatt atctggaagt tttaaaagag aatgataaaa tacaaggtga
    11281 ttttgtacta gtaatgaatg atgatagatt aaacagtatg agaaagcatt tagtacaaga
    11341 tagtaagatt atagtgataa ggagaacact taaagaaaat gaaatatatg gattattttc
    11401 aataccaaat ggaactgaag tattggttgt aaatgataca aaagaaacta ccttagaaac
    11461 gataagctta ttttacaaaa taggagtaaa aaatttaaag tttactccat atattgaagg
    11521 aaaaatttat aaaaatatag acatagctat aacgcctgga gtaaagggaa aagtaccaag
    11581 ttatataaat aaagtaatcg accttggaaa tagatatatt gatatatcta cctttataga
    11641 aataataaat ggtcttagaa tagatgttaa agaaatacgt aaaaatttaa tggcatattc
    11701 tgagagttta ataagtttag ataatggagt taaagataat tataggcaac tgtttttaaa
    11761 aatagaagaa caagatgtta tattgaatct atcaaaagat ggaataatat ttacttcagc
    11821 agatggtata ataaacacat ttaataaaga agctttaaaa attttaggta taaatgaaaa
    11881 tccacaaggc aaaaacatag aagatatcat ttctgaagat ttaaatattt tacttgaaga
    11941 caaagaaata attgatgaag tggtatttac aaataaaaaa tatataaatg taaataaaaa
    12001 aagtattttt tctatgggga ataaagctgg gatatattat aacttacaag aaataacgta
    12061 tataaaaaaa ttagaacaaa atcttactaa taaattaaga gaacaaggtc agatagcaag
    12121 atatacattt aaagatataa aaactaaaaa taaaaatatg gtaaagtgtg tagaattggc
    12181 taaaaaaata tctaaatcag aactttctgt attaataata ggagaaagtg gtactggtaa
    12241 agaattatta tcacaatcaa ttcataatgc ttccaataga agtaatcaac cgtttatagc
    12301 agttaattgt gcagcagttc cagatagtct attagaaagt caactgtttg gatatgaaaa
    12361 aggctctttt acaggagctt taagagaagg aaaaaagggt ctatttgaac ttgctaataa
    12421 tggaactata tttctggatg aaattggaga tatgcctcca ttgctacaga caaagttact
    12481 aagggtatta caagaaaagc aggttatgcc tataggttcc cataatgtta taaacataga
    12541 tgttagggtc atagcagcaa caaacaaaaa cttactaaag atgattagag aaggaaaatt
    12601 tagagaggac ctgtattata gactaaatgt attgccaata gatgtaccat cattgaggaa
    12661 tagaaaagaa gatataataa cacttatgaa tttctttttg aaaaacaata taagactttc
    12721 gccagaagtt ataactattt tagaaaaata taattggcca ggaaatataa gagagttaca
    12781 aaatgttgct tcttatgtaa gtctaatgtg tgatagtatg gtttttagag atgacttacc
    12841 accatatata agggtagaat gtgctaacaa ttatgaagat ggatttggtt atacaagaaa
    12901 agaatttgag gaaatactga ggattctata tgaaagaaga gagtcatcct ctggaattgg
    12961 aagagggttt ataatcgaaa agcttataca ggaaggtatt gagatttctg aaagcaaagt
    13021 tagaaaggtg ctatcttatt taagtgaatg tggatacata tcatctaaat ctggtagagg
    13081 aggaagtcaa ataacctcag aggggataaa actttataat aatataaatt aagctaagta
    13141 tttgatattg aaatcacata ttttgaattt agatatttaa ataataataa acttttatat
    13201 ttatagagat taatttatat tatgtcagaa agaatattgt aatttataat taaatattaa
    13261 taggttttta aaataggatt agataggtaa taggttaagt tagaataacc cattacctat
    13321 ttttatttgt aagaaaagtg tacatagaat tagaagtaaa aaatacaact aataaaacta
    13381 ttgaaaatac tagataaata ataaataaaa ataattatag attttggcat acatattgct
    13441 aattatagag ataagacgac aaaataattg ggaggtttaa tgatgaaata caaaacaaca
    13501 gggacttgtg ctacagaaat tgaatttgaa gtaaaagaaa ataaagttac aaatgtaaac
    13561 tttataggtg gatgtgatgg aaatttaaaa gggctaaaag tattagttga aggcatgaat
    13621 atagaagatg taatacaaaa gttaaaagga atagagtgta aaacaaagcc aacatcttgc
    13681 ccagaccaac tgtctctagc attggaaaat tatatgaata taaagtaata cataaaacaa
    13741 tcgattagtt aggagtttaa ttatgaaacc aataataggg attttaggaa atttaataat
    13801 aatggaaaat ggtatgtttc caggtcttga aaggtcatat gtaaataatg attatataaa
    13861 tgcagtgcta aaaggaggag gtagtccagt aataattcct gtaaatacag ataaagaagt
    13921 tataaaaaaa cagattgaaa tggttgatgg agtcttaata tctgggggat gggatatcaa
    13981 tcctcaactg tatggagaag aaacaagaga agaaacgaca tttatatatc cagaagtgga
    14041 tgaatttgat ttaattgcaa taagtatagc attagaactt aaaaagccta tattaggtgt
    14101 atgtagggga ctacaaattt taaatgtaag tttaggagga actttatatc aagataataa
    14161 tcttatagaa ggaagttata taaaacatac acaatcttct aaaagacatg tagctactca
    14221 taaagttgat gttaaagaag gaagtatttt agagggaatt ttaggaaaac aattacttac
    14281 aaatagttat catcatcaaa gtgtcaatca gcttggaaaa ggattaaaag ccatagcata
    14341 ctcaaaagat ggtataatag aagctattga gaaagaggat gaaaattttg tagtaggagt
    14401 acagtggcat ccagaaatga tggtagatta ctgtgataaa atggaaaaac tatttaaata
    14461 ttttataaat atttgttcaa atttataata taccttgggg ggattgaaca tgaacgaaaa
    14521 gaacaaaatg ggattaataa gtattatact tttaggtatt aatgcagtag taggagctgg
    14581 agtttttcta ttaccaggag atgcaatgaa atcatttggt gtagcaagta tatttgtata
    14641 tatatttgat atgttgttag ttttatctat ggcattctgt tttgctgagg ttgcaggtaa
    14701 attcaataaa aatggtgctg cctatgtata tacaaaagaa gcttttggag atttttgtgg
    14761 ttttgaagta ggtcttatga aatgggtaat aggatgtatt tcttggggag ctttaatagt
    14821 aggttttcct acatcattat cagcagtatg ggctccagca ggtgaaccac atatacaaaa
    14881 aattataatt gtagtcatga tagttgggct tacaattata aacttattag gtgtatctct
    14941 atcaaaaatt gtacaaaatg ttataactgt aggtaaacta attccattaa tactatttat
    15001 aggaataggt atatttttta taaaaggagt taattttact tcttcaacaa tggtacctcc
    15061 aggagctgga gcaacagagt ttggagcagc agcactttta atgttttatt catttacagg
    15121 atttgaatct atagcagttg cagcagaaga tatggagaat ccacaaaaaa atataccaat
    15181 agcaattata agtgtaatag taattgcatc aataatatat atattaaatc aagttgtatg
    15241 tgttggtata ctaggagatt cgttatctag tacatctaca ccagtggcag atgctgcaag
    15301 aatatgcttt ggaaatatgg gagctggatt ggttaccttt ggaaccttgg tttctgttgg
    15361 tggaatttgt atgtgtggtg cttttgtaaa tccaagaagc tgtgtagctt tagctgatga
    15421 taaaatgtta ccgagaatat ttgcaagaaa agataaaaaa ggtacaccat atgtagcgat
    15481 aatagctact atgctaatca ctataccaat agctctatct ggaagttttg ctgaattagc
    15541 agcaataagt gcagttgcta gattcataca atacatacca acatctttat ccgtattagt
    15601 gtttagaaag aaaagaccag aattagtagg tacttttaaa actccttttg gagcagtgat
    15661 tcctctaatt gctgtatgtg ttggaacatg gttattattc caagcatcta tgcatcaatt
    15721 aattatggga ttaggagctt tggcaattgg agtaccatta tactttataa tgaagtctta
    15781 taatagaaaa gtctatgatg aaaatttaaa gaaaatagtt taattatgtt ataacaattt
    15841 attgagttaa aattagacat tggcataaaa ttaaatacaa ataagtatct acaaggctat
    15901 attaaaatat tattaatttt ttattttaat atagccttat attgttatca ataaatgaaa
    15961 aatattgtaa caatagaaga acaatagtat tatgtttata gacaaaaaac ttattaggag
    16021 gtaaatttat gccaacaata acattaaaaa atggtgtaga cgtacttatt agagaaggtg
    16081 taagagaaga tgctcaaagc attatagatt tttataatga agtgggtgga gaaactcatt
    16141 ttctgtcatt tggaaaggat gaatataaaa tatctttgga ggaacaagaa aatgctatag
    16201 aatcagcaaa agcatccgat aattctgtta aactgattgc atttatagat ggtgaaatag
    16261 ttgggattgc aacgattgat tctaatcaaa aagcaaaagg aaagcatgtt ggagtattag
    16321 gaattgttgt aaaagaaaaa tattggggaa ttggattggg taaaaggctt atgttagacc
    16381 ttatagaatg gtgtaaatca aatggaataa ccaagaagat aactcttgtc actaatgaag
    16441 aaaattataa tgctatagga ttatacaaaa aagttggatt tgaagtagaa agcatactaa
    16501 agaaagaatg ttattataat ggtgtttata ctgatttaat aggaatgtca cttttattgg
    16561 gaatataatt agtgtacatt ttatctcgaa aaaagtatat taagtatggt ataattaaaa
    16621 aagaatataa cttaatataa ttttggagga cgaattatga aaaatctgtg taaaatatca
    16681 gatgattatt taaacagcaa gcttaagtat ttaaagttat tatcaaaaca atatccaagt
    16741 atatcaaaag caagtacaga aataataaat ttagaggcta tattaaatct tccaaaggga
    16801 acagagcatt ttataacaga tgtacatggt gaatatgaac catttgtaca tgtattaaaa
    16861 aatggttctg gtgtaataaa gagaaaaata gaagaattgt tttcaaatac aataagagac
    16921 agcgaaaaaa aaatgttagc aactcttgta tattatcctg aacaaaagtt agacctaata
    16981 attaagcaag aggaaaatat agatgatttt tatagaataa atatttatag acttatagaa
    17041 ctttgtaaat atgcttctag caaatatact aggtctaaag ttagaaaact gttaccagaa
    17101 aattttaaat acataataga agaacttttg catgagcatg ttaaaagtga acataaagaa
    17161 gagtattata aaagtatagt tgaaacaata gttgacatag gaatagctaa ggagtttata
    17221 attgctattt ctacagttat acaaaaattg gttgtagata gacttcatgt aataggagat
    17281 atttatgata gaggtccaag accagatata attgtcgata agcttattga acatcattgt
    17341 gtagatattc aatggggaaa tcatgatata ttgtggatgg gtgcagcctc aggtgaaaaa
    17401 acttgtatag caaatgcact gaggatatca gctagatatg cgaatttaga cattgtagaa
    17461 gacatatatg gaataaatct attgccttta gccacttttg ctatagaaat gtataaagat
    17521 gacccttgta aagaatttat tccaaaggtt aatgaccaaa gtgtaacaac aacagaaaag
    17581 tctttaatgg caaaaatgca caaagcaata agtataattc aatttaagct tgaaggtgag
    17641 gttatcagac gaagacctga atttgaaatg gaacatagac tcttgcttaa tatgataaac
    17701 tatgatgaag gtacgattaa tttaaaaggt aaaacatata aattaaaaga tacttattta
    17761 cctacaatag acaaaaaaga cccatataaa ttaactatgg aagaaagaaa tgttattgat
    17821 aaattagtat cttcatttag aggtagtgaa aaattacaaa aacatgtttc atttttgttt
    17881 tctaaaggaa gtatatattt aaaggctaac tcaaatttac tgattcatgg atgtgtaccg
    17941 ttaaatgaag atggaagctt tatgtctatg aatataatgg gaaaagagta taaaggtaag
    18001 gctcttatgg ataagatgga gtctctagca agagaaggat ttttctttaa agataaggca
    18061 gaagaaaaac tgtatggcat ggatattatg tggtatttat ggactgggaa atgttcatca
    18121 ttatttggta aagatgatat gactacattt gaaagatact ttatagctga aaaagagact
    18181 cataaagaaa ataagaaccc atattttaaa cttagagaaa atgagatggc ttgtaaaaga
    18241 ttatttgaag aatttgattt agaacttgat gaatctcata taataaatgg tcatgttcct
    18301 gtggagagta aaaatggaga gagcccaata aaagctaatg gtaaaattct cgttatagat
    18361 ggtggttttt ctagggctta ccaaaaaact actggtatag ctggatacac tttgatatac
    18421 aattctagaa ctttgcaatt agtatcgcat gaaccattta attctgctga agaagccatt
    18481 gcaaatgaaa gtgatatctt atcgacaact gttgtagtag agcataaggc aaagagaaaa
    18541 atggtgagag atactgatga aggagtaaag atacaagagg aaatagaaga tttaaaacta
    18601 cttttaatgg cttataagaa agggctaata aaagaaatgt agatgttata gaggcacttc
    18661 atgattgaag tgtctttttg ttaatactta ttaaatatat tataaagatt aataatagta
    18721 gtttatatta tacttactaa gtgaatccaa gataaatggg ttcacttttt ttatttataa
    18781 acattattaa aaaaatatag atgttttggt tatattcctt gtcctttata aatagaatta
    18841 tataaacaaa ggaggaggac aagagatgaa taaactttct gatgaaataa taaactctct
    18901 ttctacaact ataagagaaa aggtagaaaa agtctcaaac aataatctga acatagaaga
    18961 aattaggtta cgctcacaaa aaccattgat actaaatgca aactctaaag attattttta
    19021 caatcaaaaa actatgacac ttgatttaaa tcaacaaaac tcatatgtag taacaagaga
    19081 agatgtagag caaacttttc aaataatatg taaatattca atacattcat ttatggatga
    19141 cataaaaaaa ggattcataa ctttgagagg aggtcataga gtagggttag ttggaaaagc
    19201 aatagtagaa gatggacaag tcaaaaatat aaagcatata tcatctttaa atataagggt
    19261 atcaagggaa attattggat gctcggataa gattttaagt catatcataa agggaaaaaa
    19321 tcagattaat aatactttga taatatcacc acctcaatgt ggaaaaacaa ctttaataag
    19381 agatatagta agaaatttaa gtaatggtaa tgaagattat ggatttaaag gtttaaaagt
    19441 ggctttagta gatgagcgta atgagatagc aggagcttat ctaggtgttc cacaaatgga
    19501 tgtgggaata aggactgata taatagaaac ttgcccaaaa gacttgggta ttacaatgct
    19561 tttaaggtct atgtcaccaa atgttattgt gacagatgaa attggaagtg aaaaagaaat
    19621 aaaggcatta tacacagcat taaatggagg tataggatta ataactactg tgcatggaga
    19681 ttcaatagag gatatacaaa atagaaaaga attaaataga cttctggata aagagttatt
    19741 taaaaaggtt ataattcttt ctgcaaaaag aggagcagga acaattgaaa aaatttatga
    19801 tttagaagaa aagagatggt attttgcaaa ttaaaataat tattatagct ttcttgatag
    19861 gaagtagtta tttgataggt gaacaaatat acaaaactta tactcgtaga cataaacaat
    19921 taaacgattt aataagagtt ttagaaattt tgaggatgga tttatctttt ggactttata
    19981 cattagaaga aatctttaat aggataggtg gaaataaaga gttttgtttt tggaaatttt
    20041 tctatcaaat atcagaagga cttcacaatg aacaaagtaa aactttggaa ataataatat
    20101 cagaaaatat tgatgtctta agtaaagaaa cttatctagg caataaagaa attgaggaac
    20161 tgaaaaatct aatacttact ttagggaaaa gcgatataga gtcacaacaa agaatgatag
    20221 atttatctat agaaaatttg aaaaaacaaa cctatgagac aaaggaagat ataaacaaaa
    20281 aaggcgtatt gtataaaaaa ttagtgacat tcataggtat aggtatatgt attatattga
    20341 tttaatatgg ggaggtttat tatggaaata tcattgatat taaaggttgc aggtgtcggt
    20401 attctaatat cagtattgaa tatgatattg gaaaaaacag atagaaaaga ttgggcaggt
    20461 cttactacat tagcaggtgt aataatcgta ttgggtatgg taataacaga aataagtgac
    20521 ttgtttaata ctgtaagaac aatgtttcaa ctttactaaa gaggagggag taatttggaa
    20581 ataatgcaat taataggaat tgcaatcatt tcaactacac tctgtttagt aattaaaaaa
    20641 gatagaccag agatagcaaa tttcatagct ataataactg gagtaataat actattgtca
    20701 gttatgttta agctaaattt tatagtagat agtatacaag atttggctaa caaggctaac
    20761 atcccgacta tgtatatatc attaataata aaattaattg ggatagcata cttaatggaa
    20821 tttgcgatac aactttgtaa agattgtggg gaaggaaaca ttgcttcaaa actagaattt
    20881 ggaggtaaaa taatagttat gtcaatgtct ttccctatac ttttgtccat tgtagaaatg
    20941 gtggtgaata taattccata gatgtgtatc ttggaatgaa tataagtata ttagagagct
    21001 tttgttgtat tgaggtttat agagtgaaga gaggcatggt tgcttatgaa aaaaagattt
    21061 ttaccaatga ttataggttt tttatttact ttcttttttg taaatatctt tgctattatg
    21121 atatttgcta atgaagtacc aagtagtgaa gataaagaat atggtgaaac aaaaaatagc
    21181 atagataagt atatagatgg tcaattagac aagctagata taaatgagat tcaagactat
    21241 ataaataaag aaatagttat taatgatgtt aatttaaaat catttgtaaa agatttaatt
    21301 agtggagaaa aaaatatctt agatttattc aataaagatg gattgaagat attgatgttt
    21361 gatgaattta aagcaagttt aaaggtagta gcagtaattt tggtactggc tctgttatca
    21421 tctattttaa agagtctgga aaactctttt tcatcaggtg cagtaagtca aatagcaaca
    21481 tatataatat ttatcacaat ggtatcactt acacttattg gttttaaaga tgtattacag
    21541 atttgctatg atgcaataga ccatactgta ggtcttatgc aagttataat gccaatatta
    21601 ataacatttt tacttttaat tggattccca ataacgtcga ctactttgaa tcctatcttc
    21661 ataggaggag taacatttat aaatgtattt tttaaaaatt ttctatttgt atctattact
    21721 gttgcatttg gaattttaat aataaacaat ttatcaaaaa atataaggct aaagagattt
    21781 ttctcctttg taaaacaaat aaattatgtt tctattggag ctatgtttac tgtttactta
    21841 ggtcttgtat ccatacaagg attgtatgta accagttttg ataaattcag tgtaaagact
    21901 gctaaatttg ctataggtaa ttttattcct gttgtaggtg gatttgtatc tgactctgtg
    21961 gatattttat tatcttcatc tcagcttata aaaaatatat ttggaggaat agggcttatc
    22021 ttacttgttg gaatttgctt acttccagta ataaaaattt tatcagtaat agtagtgtac
    22081 aaattagcag caataattgt agagcctgtt ggagaggatg gaatatctaa ttttttaaat
    22141 gaagtggcaa atttaatgat aataatgcta gcatcagtaa ttgctataac agtaatgttc
    22201 tttgtaactg tagctatctt gacctcgata agtgtcgtaa gtcaagggta atttatatat
    22261 cagtgaaaaa taattacatt taatctaatg tttttagaga ggaggatgct atgttagagg
    22321 gcataaaggc atggatagtt agtgttttga taggagcatt tatagtaaat atagtagata
    22381 tgattttacc aagttctaag ataaaacctt atgtcaacct agttttaaac tttatgtttg
    22441 tatttattgt aataactcca gtagtaggat ttttttcaaa agatatgagt ttagaagata
    22501 gaatattaaa atctatggga aactacaaca agcagtatgt agatagtaca aatgctttgg
    22561 caaaagagac tggaaataat agtctatcca agggatatga ggatgggtta aaagaagtac
    22621 ttaaattaaa acttgatgaa tatggttatg atttagaaga tatagagctt aatggggcaa
    22681 atataaataa tataaaaata aaagaaaaga ataatagtgc aaaaagtaat aacagttcca
    22741 atgaagaaaa taaaaataat agtactaaaa gagaggaaga aaacataaac tctaatgaca
    22801 aagaaaattc taaacaagtc ttcaaaaaag gtacagagta tgggttgaac ctaaatgaag
    22861 aaaaattaaa aaacgactta ataaaggtgc tggatgtttc tatagaagat atacaaattg
    22921 ataaatagga gttgggagaa tgttgaaaaa cttaaatgac aaagataaga gaaaggtata
    22981 ttcactaata actatagcag gaatatgtgt ggtttcatta gtattattat cttgttttcc
    23041 tagtagcaaa agcgataaac aagttggaaa aacagagact aataaaaatg ctgaaaagca
    23101 agtcactaaa gaacaagaaa aagatgattt agagtcaaaa ttaacagcaa tactatctaa
    23161 aattgatggt gcaggagacg ttgatgtaat ggttacattt gaatcaagtg aagaaataca
    23221 acctgctttt aattcaaata atacaacaga aacaacagag gaaaaagatg cacaaggtgg
    23281 agaaagaaca gttacgactt ctagtgaaaa taaaacaatg ataacttcaa attcaagtga
    23341 ccctgtagtt ataaaaacta cagagccaaa gataaaggga gtgatagtgg tagcaagtgg
    23401 agcaagtgac ccaagtgtta aagagacact ttatagtgca gtacaaacat cattacaagt
    23461 agctggtcat caagtagaaa tatattctaa ataaatacat ataaccgggg ggataaatga
    23521 atgaagttta attataaggg aagaggattt gtaataataa ctttaactgc aatgttagtg
    23581 gtagtaggaa cagtgaatta tcaactaagt aagaaatctt tattagaaac atcaaaagag
    23641 tttaaggcat atgaagaagc acagttgcaa aaaaatactg atgatagtta tagtagtaag
    23701 acagaggatt ctagtaatgt agataaacaa ggtggtaagg aaagtgctga tattgatata
    23761 gtcgatagca aagctagtaa agtaaaagaa aaggcaactg agacaagtaa ggaaataaaa
    23821 gctcaattat catcagagaa aaatatgaaa aaggcatctt atattttaga tatgaaaatg
    23881 aatagagaaa aacaaagaaa tgagttagtt caagatttaa atgaaatgat aaataatcca
    23941 tctacaacag aagaatctag aaaagaagct tctaatatga aattaaatat agttaaaatt
    24001 caagaaaaag aacttcaaat agaaaacctt ttgagtacaa aaggatatga agaagcgtta
    24061 gtttatataa gcgataacaa agttaatgta gttgtaaatg aagctaaatt agaaaagaaa
    24121 gatgcagcaa aaatatttga tttagttgca gaacaagcca atgtgaagta tgaaaatatt
    24181 aaacttacaa ataataatag taataagtaa agtataaacc tcagaattaa ctgaggttat
    24241 tttcttgcaa agtagacttg tatttggtat tattatactt ataaaaatag ttccttaaaa
    24301 tcaggaggta agttttaata tggaagataa taaatttgga caagtaaaaa tatctaatga
    24361 tgtaatagct acaatagctg gtttagcagc attagaagtt gaaggcatag aaactacagc
    24421 aacattaaca gataagttgt taaaaaataa tggagtaaaa atacaaatcg aagaagagga
    24481 tgttaattta gatgtaatgg ttacgataaa gtatggaatg tcaataccag atacagcttt
    24541 taaagttcaa gaaaatgtaa aaaatactgt tgagacaatg acaggactga aggtttctca
    24601 agtaaatata cacattcaag gaatcagctt taagaaggat aaagttgata aagaagaagc
    24661 aaaagcaact aagaaaaatt aatattagcc ctctgaaaag tcagagggtt ttttgctggt
    24721 aattgatttt atatggataa ttaaacttaa aggagaattt tgattgatga aaaaagatag
    24781 ggcacaaaag agtacaacaa gagaatatat aatgaaactt atataccaaa taaatattaa
    24841 taaagaagat tttgaaactt tagaagataa agtagataat tttttaaaag ataattcaga
    24901 acatattata aatagatata aagaacttgc acttcaatac tcaaaaaata caaatttaaa
    24961 gttagaagat actgaaattg aagatgttat agacaaaaaa tatataaata cagtatgcaa
    25021 agcattgaaa gaaaatcatg acaaaataga tgagttaata aataagcatg ctaaaaactg
    25081 gacagtagat agaatgccaa aggtagatgt ttctatactt agattgtctg tgtgtgaaat
    25141 actttattta gacactccta ataaagtatc aataaatgaa gcagtagaac ttgcaaaaat
    25201 atattgtgat gataagtctc ctaaatttat aaatggtata ttgggaagtg ttgttgatga
    25261 aattgggaaa taatataata attggaattg atactagctg ctatactact tctatagcag
    25321 ctatctcttt agataagaaa gttatattca atgaaaaaat aatgttagaa gtaagggata
    25381 attcaaaagg tttaaggcaa agtgaagctg tatttcaaca tatcaataat ttagggattc
    25441 ttagtgatag gataaaatct tttaaagata agtttaatgt agaaggagtt tgctcatcaa
    25501 aaaaaccgag acctgttgaa aactcatata tgcctgtatt caatgtaggt cataattttg
    25561 gaaaattatt gtctagtata tatggttgta gattttatga gactactcat caagagaatc
    25621 atattgaagc aagtttatta aatagtaaat taaaaaataa taataaattt atttctgttc
    25681 atatgtctgg tggtactaca gagatacttt taacaagcaa acaagatagt catcacaatg
    25741 tatgtgatac taatttaggt aaaattgcca aaataagtat taaaaaagat gataaaagta
    25801 agttatacaa taattttgga tataatatag atataattgg aggaagtaaa gatattagct
    25861 ttggtcaact tatagataga gtaggaatta agcttggata taaatttcct tcaggaaagt
    25921 atttggatga aaatgcttta aattgtaatc ttaaaataga aagtggtctg aaaacttctg
    25981 taagagatgg gtatatgaat ttatcaggat tagaaaatca ggtaaataag attataaatg
    26041 ataatggaga taatactaat caaaaagaat atatatctaa attagtatta gattcagtag
    26101 ttagaaatat gtttaaatct ctagtgtatt tatgtgaaac ttataatgta aatgaagtag
    26161 tatttgctgg tggagtttct gcaagtaagt atattcttag agaattaagc atgaagttaa
    26221 gaaaaaagca tatagaagct tattttacag aaccacaata ttcaactgat aatgctgtcg
    26281 ggtgtgctat aataggattg aataactttt taggagaaag agtatgaaac taagagcttt
    26341 agatataagt gaagcaaact catatattaa aagaatttta ataaacgacc caatactttc
    26401 taatcttaaa gttaaaggag aaatttctaa ttttaaggtt catagtagtg ggaatgtata
    26461 tttatcactt aaagatgaaa catcaaagtt aaactgtgta atttttaaaa gtaattttaa
    26521 tcgcaattta aaattagata atggtgtaaa aattatagct aatggatata tatcagtcta
    26581 tgaaagagat ggtgcgtatc aattatacat taatgaaatt gaaatagagg gaataggaaa
    26641 tttgcacata gagtttaata gattaaagga aaaacttaat aaagaaggat tatttgaccc
    26701 taaatacaag atacctatac ctaaaatgcc aaactcaatt ggcgttataa catctccaac
    26761 aggtgctgtt ataagagata taataaatgt aataaaaaga agatatccga aagttaatat
    26821 aaagctttat ccagtaacgg ttcaaggaga taaatcagct gaagaaatct gtgaagcaat
    26881 tagatttttc aatcatatga agaatgttga tacacttata gttggtagag gtgggggttc
    26941 aatagaagaa ctttggtctt ttaatgatga aatggtagca agagaggttt ttaattctca
    27001 aattccgata atatcagcag ttgggcatga aacggatttt actatttgtg actttgtgtc
    27061 tgatatgaga gccccaacgc catcagcagc agctgagatt gctactccat cattggatga
    27121 tataaactat aaacttggaa acataaaaag taggatgagt aagtctctta caaatcaaat
    27181 agagctagac caatataggt tagaaacagt atttaataag ataaataact atttagattc
    27241 gtacacaata aaagataaag ttatacaatt agacaaaata tatgataaaa taatttttgg
    27301 aatagaaaat aatttaaaat tagaagatga aaaattagta aaaattggag cattactcca
    27361 taatttaagt ccattagcta ctatggatag aggttatagt ataactcaaa aaaatggaaa
    27421 agtaataaat agtataaaag gattaaaaat aaaggatagt atagatatag tattaaaaga
    27481 tggaaattta gaatgtatga tagataaaat tgaaaataaa gagggatagt atgaatttaa
    27541 cctacgaaga agcttataaa agattagaaa gtattttaag tgaattagaa tctaaaaatg
    27601 ctagcttgga tgaatcttta agcctatatg aagaaggtat aagcctttat aaacattgta
    27661 ataagctttt agatgatgct aaattgaaaa taagtaaatt taatcaattg ggaatagaag
    27721 aagactttaa aatagaggag gaataaaatt ggaatttaaa caatgtctaa aagaaaaagc
    27781 aagttttgta gaaaaagtac ttaaagaata tatgcctaaa gaagaagggt atcaaaaaac
    27841 tgttattgaa gctatgaact atagcttaag tgctggaggt aaaagattaa gaccaatact
    27901 tacattggag gcttgtaaaa tagttggagg taatgaagat gaagctattc cttttgctat
    27961 tgcaattgaa atgatacata catattcact aatacatgat gatttgccag ctcttgataa
    28021 tgatgattta agaagaggaa gaccaacaaa tcataaagta tatggagaag ctatggggat
    28081 tttagcagga gatgctttgt taaactatgc ttttgaagta atgcttgcag gctcaatcaa
    28141 taaagaaaat ccagaaaagt atctaaaagc tataaatgaa attgccaaag gtgctggtat
    28201 atatggaatg ataggtggtc aagtagtaga tgtagaaagc gaaaataaac aaattgaaaa
    28261 agaaaaatta gattatatac atatgaataa aactgctgca atgatggtag gctgtatgag
    28321 agcaggagct actataggtg gagcaaattc tgaacaaatg gaagaaataa ctaaatatgc
    28381 aaaaaatatc ggattatcat tccagatagt agatgatata ctagacatag taggagatga
    28441 agctaagtta ggtaaaaagg ttggaagtga tatagaaaat cataagtcaa catacccatc
    28501 tcttttaggt ttagataaat ctaaagaaat tgcacataat ttgattgatg aagcaaagaa
    28561 aagtatagaa aaattatctg atgatgtaga ttttttaaag ggattggctg aatatataat
    28621 agatagagaa tactaaaata tacagctaaa atcgaggagg gaaaaatgga ttttttttcg
    28681 gagattttta acaatggggc tttgggaata agtctgattg cttgtttctt agcacaattt
    28741 ataaaaatat ttactggtaa ggaaaaaaga attgagttat caagaatact tatttcagga
    28801 ggtatgccta gttcccatag ttcttttgtt acaagtttag ctacagtggt aggtattgaa
    28861 aaagggttta attctactga ttttgctata attaccgtgc ttgccttaat tataatgtat
    28921 gatgcagcag gtgttagacg ggctgttggt aaacaagcta ctatattaaa tcaaatggtg
    28981 gcagatatac agcatggaaa gcatatagag cagaagaaat taaaagaatt aataggtcat
    29041 acaccactag aagtttggtt tggagcttta cttggaatag taacagcttt aatattgatg
    29101 taaattgaaa atttacagaa taaaggtgag gataatatgt ataaatattt agataaagta
    29161 aattctccaa aggatataaa aaatatgagt atagaagaaa tggatttact tgcaaaggat
    29221 ataagaaagt tcttagtaaa atctgtttca aagacaggag gacacttagc ttctaatcta
    29281 ggagtggttg agttaacatt agcacttcat aaagtatttg atagccctaa agataagatt
    29341 gtatgggatg tagggcatca atcttatgtt cataaaatag ttactggaag aaaagattgt
    29401 tttgtatctt tgagacagtt taatggacta agtggttttc caaaggagaa tgaaagtcct
    29461 catgatattt ttgatacagg acatagcagt acatctattt ctatagctac aggtattgcc
    29521 tgtgctaggg atataaaaaa agaaaactat agtgttatat ctgtgatagg agatggttct
    29581 ataacaggag gtatggcact tgaagcttta aatcaattag gatatataga taccaatatg
    29641 atagtaatcc ttaatgataa tgagatgtcc atagataaaa atgttggagg aatgtctaaa
    29701 tatctgtcaa gtattataag aaactcaaca gttgagaaaa tgacagatga agttgataaa
    29761 attttaaatg ttacacaaac aggtgaaatt ttatctaaga ctgcacatag atttaaagat
    29821 aaactaatgt atagcttttc tcctcaggac tgttcatttt ttgattcatt aggtataaga
    29881 tattatggac ctatagatgg ccataatact aaagaactaa tagatatatt gagaaaagct
    29941 aaacacaaaa aagggcctgt tcttttacat gtaattacga aaaaaggaaa agggtacaga
    30001 tttgcagaag aacaacctga taaatatcat ggagtatcaa agtttgatat aaagacaggt
    30061 gttacatctg caaaagttaa gtctatgtca attagtgttg gagaaaaact tgttgatatg
    30121 gctaatagta atgaaaatat agtagcaata acagctgcaa tgccatctgg tacagggtta
    30181 aacctgtttg aaagtgcata tccaaaaaga tattatgatg ttggtatagc tgaacaacat
    30241 gcaacaggat ttgcagcagg tcttgcaaaa aatggtatga aaccttactt tgctgtgtac
    30301 tcatcatttt tgcaaagggc atatgaccaa gttattcatg atgtatgcat aacaaaaaag
    30361 ccagttactt ttcttataga tagagctgga ttagttggaa atgatggaga aactcatcat
    30421 ggtatgtttg atttaagtta cttaaattct attccaaata ttgtagtaat ggctccaaaa
    30481 gacacaagag agatggagct tatgatggat ttgtcattaa aattagattg tccactagca
    30541 attagatacc caagaggaag tagttattac ctagataagg gagagtatgg agagattgta
    30601 ctgggtaaat atgaggtatt agatgacggt caagatacag tcatactttg tattggaagt
    30661 atggtaaaac atgctttaga ggctaaagaa atattatcaa gagaaggaat aaatccgaca
    30721 atagttaatg ctagattctt aaagccaatt gatgaaggta tgttaaaagc attattaaaa
    30781 aatcataaaa atgtagttac tatagaggat aatattgtaa ctggaggatt tggaagtaga
    30841 ataaataagt ttattataga taatgaatat aacgtaaata tacttaatat agcaatacca
    30901 gaagaatttg taaaacatgg caatatagat gaattatatg actttgtagg attatcgcca
    30961 aaaagtattg ctgataagat aaggaaatta gttattgagt aaaaatctaa tgtagatatt
    31021 gtaaattaaa atttatataa aatatagaat ttatcaatta gaataaatat caagtgtgtt
    31081 acttcaagct actttagtta tcattaaagt agcttttaac agaaaggtaa ttgtatgaaa
    31141 aaaagaatag atttattatt agtagaacaa gggtactttg aaagtagaga aagagccaaa
    31201 aaagcaataa tggctggatt ggtttttgtt gataatcaaa ggtgtgataa ggctggtaca
    31261 gaagtaaaag aagattgtag tatagaagta aaaggaaatc caataccata tgtcagtaga
    31321 ggtggtttaa agcttgaaaa agcaatgaaa aactttgatt tgactattga tggaaaggta
    31381 tgtatggata taggggcatc cacaggtggt tttacagatt gtatgctcaa aaatggagca
    31441 ataaaagtat tttctataga tgttggttat ggtcaacttg catggaaatt gagacaagat
    31501 gatagggttg tgtgtatgga aagaaccaat ataagaaatg tgacaataga agatacaaag
    31561 cagtttgctg attttgcgtc aattgatgtg tcttttatat cgttaaagtt agtacttcca
    31621 aaggcaaagg agttagtacg tcatgatggg gaagttgtcg ctttaattaa acctcaattt
    31681 gaagcaggaa gagaaaaagt aggtaaaaaa ggagtagtta gagaaaaatc tacacatata
    31741 gaagttataa aaatgatttc tgatttctca gtcgaaaatg gatttgagat tttagggtta
    31801 gatttttctc ctattaaagg tcctgaaggt aatatagaat atctaattca tttgagaaat
    31861 ggaaatgaag gatatgaatt tgatggtgag acatacaata acaaaatagt agaagttgtt
    31921 gaagcttctc ataatttaga caaataggtt aaaagggggc ttagatttga tcctcgaatt
    31981 atatatgaaa aattgtgcct tagttgaaga actaaggttg aatattgata aaaacttaaa
    32041 tatacttaca ggtgaaactg gttcaggaaa atctataata atagatgcac ttggactttg
    32101 tttaggtgat aaatatgata ggtctttttt aagaaaagga acagataagg gacttgttga
    32161 ggctgtattt ttttcagaca atagatatct taaaaaaata ttagaagaaa atgatataag
    32221 tatggaagat gataatttat tggtaataac taggttgata tactcagatg gtaagagtac
    32281 tgctagagta aatggaagga ctgttaaagt gtctcttctt aaagaaattg catctacact
    32341 tatagatata catggtcaac atcaaaatca agctttgttt aataaagata ctcatttaaa
    32401 atttctagac ctttttggag aaaatgaatt ggaagagttt aaaattgctt ataaaaatgt
    32461 gtaccataag tatagtgaag taaaaaaagc tttaaattgc ttgacagaaa ataaagatga
    32521 gatgcaaatt caacgagaaa tagatttatt aagatttcaa ataaatgaaa ttgaagctgc
    32581 aaatctaaat aagaatgaat atgaagattt attaaaacaa agagaagttt atagaaatag
    32641 tgaaaagata tataataatc taaattcgag ttatagcaag ttacataatg gtgagtataa
    32701 tgttattgac ctaataggtc ttgcatctaa ggaacttaat gacatatcta aatatgacag
    32761 tgttttaagt gaatatagtg atactgtaga aagaatcatg tatgagttac aagacatatc
    32821 tggtgagata agaaattaca aagataatat agactttgaa ccttatgagc tagagcagat
    32881 tgagcttaga atcgacgaga ttaataactt aagaagaaaa tatggagaca gtatagatga
    32941 tatatttgag tattatggaa aaattaaaga tagattagat gaaatattaa acagagatga
    33001 aagagttgaa cagttaagaa gcaaactgat gaatatagaa gaagatttaa aaataaaagc
    33061 cagtaaattg actaaagcaa gaatagaagt agcaactact ttagaaaaaa tacttcttga
    33121 tgaattaaaa agcttaaata tgaaaaatgt aatgttcaag gttaattttg aaaaaggtcc
    33181 atttacttta gatggagtag atgatattga atttatgata tcttttaact taggagaaga
    33241 tattaagcct atatataaag ttgcatcagg tggtgagatg tccagattta tgttagcgtt
    33301 taaaaccata ttggctgata tagatgatat tgatacatta gtgtttgacg agatagatac
    33361 tggaataagt gggatagcag cacagatagt tggtgagaaa ttgagtgata tagcaaagaa
    33421 aaaacagata atatgtataa ctcatttacc tcaaattgct gcaaatgcag acactcatta
    33481 ttgtatagag aaagatactt caaataatag gacgtttacc aatgttagta agttaaatga
    33541 atctcaacga aaaaatgaaa ttgccagact tatagcaggt aacaatataa cagaaaaaac
    33601 tattgaacat gcaagtgaaa ttattgagtt ggctaaaaaa tgttagtgaa aaacaagcat
    33661 tttaataggt gtaaagaatt tttatagaaa tgctttacat ctatttttta tgatgaaatt
    33721 attttaaaat atctagtgcc tatattgaag aaaagtaggt ttgaaaatgg aatgaacttt
    33781 gtataaattt gtaactttga aatttctaaa tgcttaagta taatattatt tattaaggta
    33841 gtagtgaggg gaggcataaa atgaataaaa aagatactat gcacttaatt tttataattg
    33901 taatttttat tttattatgg tatattgtgg tagcagtaag tgagattaat aaaaatattg
    33961 aaagttgtag taacaaatta gattatttgt cacaagagct tatgagtact aagtcggata
    34021 ttagtaatac tataaatgaa gaaatgtcaa aaagctatat aacaaaaagt attgacttaa
    34081 aagtgaaaaa aatcgagaaa aaagaatgta ttattgatat agatgttcaa ttaagtaaac
    34141 ttggaaaaaa tggaaaagta ttttttatgt ataaagaaga tagtgataaa tggaatgaaa
    34201 ctgagatgac aaaacatgga gaattatcat atgcatgtga aattaagata aatacaggaa
    34261 gtgaatatga ctataaagta gttacaagtg gagctatatc tgaaagttct gatgtgcaaa
    34321 aattgactaa atctgattat atgcctgaac aacccatatt taattctggg ataagagata
    34381 atagagaata ctttattgaa atagtagaaa atagtaatct tttcaatcat gagagtgaaa
    34441 agtcaaaaaa taaagtttat gataatatta gattagaaaa agtagatatt attgtaaatg
    34501 aaggaaaaaa agacactata tacaaagcca aattagctga aggcttagat gatggcaaaa
    34561 ctaataattc aaatagaaat caagtgaatt atgaagtaag ttttcctaaa agggatattg
    34621 atgacataat ttatattaaa gctaaactta catacaataa tggagtagaa tatacaaagg
    34681 atataactga agatataact atgggattac aagatttaga aaaataaata catatttaaa
    34741 taaatattca aatagatttg ttcaataaaa tagagtataa ataaaactgt agtagtttta
    34801 cttatactct attaaaaaat tataatttta attccatata tctagcccct tcaattggat
    34861 tataagtata aggttctata tcataaaaac caaacttttc gtataatcct tgtgcacttt
    34921 tcatgcttgg aagagtatct aatctcatgt gtgtatatcc aaatttttta gcttcttcaa
    34981 tgatttcttc caatagtatt tttcctattt ttaatcctct aaattgattt cttacatata
    35041 atctttttaa ttcacatatt ttaccttcaa gtttttttaa agcaacacaa cctgccaaat
    35101 tttcatcaac aaatgccaat atcaatgagc ctgaaggttt tttatatttt cctggaagtg
    35161 tttttaattc attattaaag tcttgaaaac ataagtctat atttagagaa tttgaatatt
    35221 cagtaaatag aagttttacg ttttcaaggt tttctaaatc tttttcttca acaaattgta
    35281 aagttatatt ttgagccatt ttatccgcca ttatatacac atgtttatat aatgacttca
    35341 cctccttgat atatgtatat ttttcttaat atcaattaga ttttaatacc attacttttt
    35401 caccaccata gtcaagctct ccattaaact caaatccaaa atctttataa agcttaatag
    35461 ccattttatt gtcttcgaat atactaagat atagttcatc acagttatat tcatttttaa
    35521 gatgatttac aagaaaatct aatgatgctt ttccatatcc tttaccttga tattttgaat
    35581 caatcataaa tctatcaagc caaactctat catcttctaa acgaccatac atagcaaatc
    35641 ctattaaaga attttcatca tatattccaa caggtaccca agctgttata aatttagatt
    35701 cagcaataga aagtgcattg ctttctatat aatctaactg acttttatct acagacaaac
    35761 taactaaatc atgccaatta tttatgtctg caattcttac atttaatttc aagatattac
    35821 cgcccttcaa actttttgtt acaatctaat actatcatat tatgtattaa aaatcactta
    35881 ttaagatttt aaataaactt tttaaatgaa taaattctca ggaaaaagga attataaata
    35941 cataataata cagcatagga gtagatggat atatgaacaa aataaataaa aatttcaaaa
    36001 atatttggat aatattagga gctgtatcga tttttaccat ggttataatt tttaataaaa
    36061 attgtaatgt taataaagag actcaaatag aagcttttac aattaagaat catgataaaa
    36121 aatttgtata tcctatggga aatataattg gagtaaaagc aaatacagat ggtgtattgg
    36181 tcttaggata tgaggaagag gatgtagact atattggagg catacaaatc ggtgataata
    36241 tagtaaaaat agataataaa aggataaaaa atagtcaaga tgtatcagag attttgaata
    36301 agattaaaaa aagtaaagtt gaagtgactt ttgagagaaa aaataagtat aaaacagaag
    36361 taatagagac taaaaaagaa aatggcaagt ataaacttgg attatgggta agagataaaa
    36421 tatctggaat tggaactatg actttttacg accctagtat ggaaaagttc aaagcaattg
    36481 gtcatgccat aaaagattcg gatactaatg aactattaaa gataaagcaa ggatatatat
    36541 ataagccaga acaattaaaa atagtaaaag ctagtaatga aaaagtaggt aaaataaaag
    36601 gagattttaa tgacagcaat ttaatgggta atttctcaaa taattcagag ttaggtataa
    36661 gtggtaatat tacagaaaac cataataaag agtttaatgt agcaaataaa gaaaagcaat
    36721 taatagaagt tggaagaccg caagatgtaa aaataggagg tgcagtaatt ctttttgagg
    36781 ataaaaacaa aaatataaca agctatgata taaaaataga aagtatagta tatgataaag
    36841 gaaattatag agatatggta ataaaagtag tagatgacaa gttattggaa tacacaggag
    36901 gtatcgtaca ggggatgagt ggagctccaa taatacaaaa taataaaatt attggtgcaa
    36961 taactcatgt ttttagagat aatccgaaaa aaggatatgg tatttttata gatgaaatga
    37021 taaaattgta ggtgaggcat taaaaaattt tattatttta tcaattatct aggaggaata
    37081 taattttgga gtgtcgaata tgctttagag tagataatta ggaagcaatt gtgtaaaaag
    37141 tttagttttc tgtaataaga agatgttttt taatgggggg atttttagtg gaaaaaatca
    37201 aaatagtttt agcagatgac aataaggatt tttgtcaggt attaaaagag tatttgtcta
    37261 atgaagatga tatcgatata ttaggcatag ctaaggatgg aattgaagca ttagacttag
    37321 taaaaaagac acaaccggac ttattaatac tagatgtaat aatgccacat ctagatggat
    37381 taggtgtaat tgaaaaattg aatactatgg atatacctaa aatgccaaaa ataatagtac
    37441 tatcagcagt aggtcaagat aagataactc aaagcgcaat aaatctagga gcagattact
    37501 acatagtaaa gccatttgat tttgttgtgt ttataaacag aattagagag ctagtttcta
    37561 atagagttac acaagttgag ccaaaaccta gaccagttca agagactcaa atgactagaa
    37621 gtgattttgt taagaatgta ggaaatatag agacagaaat cacaaatata atacatgaaa
    37681 taggagtacc agctcatata aaaggatatt tatatttaag agaagcaata aaaatggtta
    37741 ttgataatgt tgagctttta ggtgcagtaa caaaagagtt atatccaagt atagctaaaa
    37801 aattcaatac aacaccaagt agagttgaaa gagcaataag acatgcaata gaggttgcat
    37861 ggagtagagg aaaagttgac acaataaatc aattatttgg atatacggta cacaatacta
    37921 aaggaaaacc aactaattca gaatttatag caatgattgc tgataaatta agactagaac
    37981 atagtatggt taaataaaca agacataaaa agtaaggctt tttaattaag gcattggcta
    38041 taaatgcgta ttacaagcag cgaaacggta taaccactag ggttataccg tttcgctatt
    38101 ttaataaata taaaaatttt atttattatt tgcttactat atcaatataa taattttatt
    38161 atactatgga tatagtatgt gtctttacaa gttgtaaact gacagtggtt tattttttaa
    38221 tataaatatt gactttgatg caggtaaact ttgtattttt aagcgtatta tggaatatgt
    38281 taaataaaaa aatgatgaaa tatagtattg taaatgccaa agatgcaaaa caaacttaaa
    38341 acatttattt tattgttaag taatgctata atataatgtg attttaataa tgatagtgga
    38401 ggtttaaata tgagagtcga ggcccctata aaagtagatc gaaaaaccaa aaaacttgct
    38461 aaaagagttg aaagtgggga aatagcagtt ataaatcata tagacataga tgaagttgct
    38521 gcaaactctt tagtagaagc taaaataaaa cttgtcataa atgcggctcc ttctataagt
    38581 ggtaggtatc ccaataaagg tccagggata ttaactgaaa ataatatact aataattgat
    38641 aatgttggag aagagttatt tgaagaatta aaagaaggag aaactataga agttgtagat
    38701 ggaaagatat atagaaaagg aaaattttta ggtgcaggag aagttttaga caagtatgag
    38761 gtttcacacc aaataaaggc tgcctatgag aatttagctg tagaattgga tagatttata
    38821 gataatacta tagattatgc taaaaaagaa aaaggattta tacttggaga agtagaaatt
    38881 ccaaaagtga aaactaatta tgctaataaa catgtattga tagttgtaag aggtcaggac
    38941 tacaaagaag atttaagtac tatgctttct tatatagaag aggtaaagcc agtattggtt
    39001 ggtgttgatg gaggagcaga cgctttaatt gagtttggat atactccaga tgtgattgta
    39061 ggtgatatgg atagtgtaag tgatgaagct ttaaaaaagg ctagtgaaat agtagtacat
    39121 gcttatacag atggaagagc accaggtctt aaaagggttg aggaattagg cttagatgca
    39181 gttgtatttc ctgcaccagg aactagtgaa gatatagcta tgcttatcgc ttatgagtat
    39241 aaggctgagt taatagtagc agttggtaca cattcaaata tgattgattt tcttgaaaaa
    39301 ggaagaaaag gtatggcaag tactttttta gttagactaa aaataggttc aaagcttata
    39361 gatgctaaag gcgttaattt gttatacaga agtaaattaa aaataaagta catatgggca
    39421 ttaatagcaa cagcattatt tcctgtgttg gtagttgcat cattgtcacc aggagttcaa
    39481 cagttcatac aactaatgca attaaagttt agagtattat tacagatgta aattttagga
    39541 ggataaatat gcatattaat atgaaatatt atatagtcac tataggggct atatttatag
    39601 ctttgggtat aggcatgtta gtaggattta atttaaataa taatcaacaa ttaagtgaac
    39661 aacaagcaaa cataataaat gatttggatg ataagtttga tatcttaaaa gaaaaaaatg
    39721 ataaacttga cagtgactta gcaagtgtaa atagagatta tgaagaggca gttaatttta
    39781 taaataaaaa tgtagataag attttagctg gttcgctgaa tggtaaaagt ataggaataa
    39841 tatctgctaa tgaaaatgac gattatacaa aaaatataga agacataata aataaatcta
    39901 atggaagcat tgcatttaat ataatattaa aagaaaacat aacaaatcca gaaaagttaa
    39961 aggaaatgtc aactaaacta ggtacagatg taaaaaatgc aaatgatgca gttaattata
    40021 taattgacac tcttaaaaag gaagatgcaa gtgacatttt aacatatctt caagaactag
    40081 atgtaataaa gtttaatttt attggagata catatctaaa atatgattcc gttgtaatag
    40141 ctggtggaaa tgatgcaaaa gacagtacaa aacagtttga aaaaatagaa aaatttgtag
    40201 tttcaaaact taaatcagag aataaatatt tagtagaagt tcaaaataca ggagttaaaa
    40261 cttcttatgt agaactatat tctaaaaaca aagttgcaac tatagacaat attgatgaag
    40321 gtataggaag tatatctcta gctattcttc tacaacaagg taatatagtt ggtaattttg
    40381 gtagattgga tactgcaact tcattgttgc catctattaa atagaaataa ttttaaggag
    40441 agaaaaaatg gattcttata taagtataat aataccagct tataatgaag aaagtagaat
    40501 aaaatataca ttagaaagca tattggacat taagcaaata aatgaaataa tagttgtgga
    40561 tgatggttca attgacaata ctgctaaggt tgtatctgag ctagaaaatg aaaagattaa
    40621 attttttaag ttagataaaa atagaggtaa aggatatgct ttaaattatg gtatcaaatt
    40681 agcaatgaaa aatgcagata ttataggttt tctggatgga gatttaggaa gttctgctaa
    40741 agaagttgaa aaattaatag tacctatatt aaatggtgag gcggatgtta caatagccaa
    40801 gtttcctcct gcaaagagaa aaggaggttt gggatttgta aaaggtttag ctaaaaattc
    40861 tgtgtttgag atgactggtg ttgagttaga tgcaacttta tcaggtcaaa gaatatttaa
    40921 aagagaagtt ttagaaaagt ttgatgaaat accttttgga tatggagtag aagttggaat
    40981 gaccattgat atattaaagt atggatttaa aattaaagaa gtattagtaa atatgactca
    41041 taatgaaaca ggaagaaatt taaaaggttt tattcataga gggaaacagt attatcacat
    41101 aaaaaaggtt ttaggacaaa aaaagaaaga atggaggtaa tatcttagtg aaagattata
    41161 tactttatac cattttatta ttaactggat tatttggaac ctatgctgta attccactat
    41221 ttaaaaattt attgataaat ggaaatgtac ttagaccaaa ctataaaaaa gatatgatac
    41281 cagtaagtat gggaattgta tttttgccta tgattgtaat caatggaata atacttgctt
    41341 tctttactac agaatttaag gatttagcgt atatatttat gtttatgttt ggtatgatat
    41401 ccatgttttt tgcagggata ctagatgatg tcattggaaa tagagatgta agtggtttaa
    41461 aggggcattt taaaagttta tttaaaggaa gtcttacaac aggaggtttt aaagctttat
    41521 ttggtggatt tgtagggctt atagtttctg ttgctatatc aaaagacata attgatataa
    41581 tagtaaatac actaataata gctctatcaa ctaatttaat gaatcttttg gatttaagac
    41641 caggaagggc aataaaagca tatttattca taatggtaat tatattttta acattgacag
    41701 gatttgttca agttcttcca ttacttatag taccaaatgt acttgcatac tttaattatg
    41761 atttaaaagc aagggctatg atgggagata ctggttcaaa cgtccttgga atatctattg
    41821 gaatgctcat ttcttttggg tatccattta acattagatt aggatggtta atatttgtag
    41881 ttattatgca tatattcact gagaaatact cattaactaa gataatagaa aaaaataaac
    41941 tattaaattt tatagataaa ttgggaaggt agtattatga taagcaaaag agtggggatt
    42001 gttgaatcaa tagtaagtca aactgaaaca ctagatgata taagagtaaa tataaatgga
    42061 gaaatacaaa gggcatataa ttatcccaaa atatctggaa ctataaatat aggtgacgaa
    42121 gtggttttaa atacaacagc agtagaactg agcttaggta caggtggata ccattttgta
    42181 ataactaatt taaataatat agaatctact ttaactgaag gtggacatat aatgaaactt
    42241 agatatacgc ctcttcaaat aaaagtggat tctgttgagg aacaagaaag tatttatcat
    42301 gataaatttg cgaattttaa aggattagaa ggtctttctg ttgtagtagg gactcttcat
    42361 agtatgttaa ctccatttgc agcttcattt aaaagaaata atccaaataa aaaattagtg
    42421 tatataatga ctgatggagc atctcttcca atttatttaa gtaaaaatgt ggatacttta
    42481 aaagaaaaaa aattaataga tagtacaata actataggaa atgcgtttgg tggagattat
    42541 gaatgtataa atatatatac tgcattaatt acagcaaaag aaatactaaa agcggatgca
    42601 gtatttgtca gtatgggacc tggaattgct gggacaggaa caaaatatgg atttacaggg
    42661 attgaacaag gctctattct tgatgctgta aaaaaacttg aaggaagagc aattgcaatt
    42721 ccaagaatta gttttgctga caaacgagaa agacatcaag gtatttcaca tcatagtatg
    42781 actgtattta aagaaattgt aaatgtaaat gtagacatac caataactat atatgatgat
    42841 gaaaaattga actttataaa agagcaaatc aatttaaatg gtttagacaa aaagcataat
    42901 ataatttata tagataataa taaaacgaaa gaggatttag actattttaa tctaaaagta
    42961 aagagtatgg gaagaaatta tgaacaagat gaggcatttt tcaaagctgc aagcacagca
    43021 gcatattact taatggaggt ttaagatggt attagaagaa aaaactatta gtagtgatag
    43081 ggtttataca ggtaaagtaa ttactttaaa ggttgatact gttgaaattc cagggcaagg
    43141 atatcaaaaa agggagttag tagaagttgg tggagcagta ggaatagttg caatcacaga
    43201 tgataataaa gttgtgttag ttaagcaatt tagaaaacct atagaaaagc caatctttga
    43261 aattccagct ggtaaactag aaaaaaatga aagtccaaaa gaatgtgctg aaagagaatt
    43321 aaaagaagaa acagggtata gtgcaaaaaa tattaagcta atacataaat ttttcacttc
    43381 agcaggtttt tctaatgaga taatgtttgt atatttagca acaggtctta ctccaggaga
    43441 gaataattta gatgcagatg agtttttaga tgtctatgaa attgagcttg aagaagcata
    43501 taacatggta ttaaaaaatg acgttgaaga tgcaaaaaca tctattggat tattattagt
    43561 aaaagatatg tttaaaaatt aatatttata aaatgaataa ccctttgtcc taaagcatat
    43621 tattttataa aggacaaggg ggaattaaat tgagaagaac atatagaaaa aatgatttta
    43681 gagaattaaa tagacaaata attattatag gattgttgtt tatgatgtct attgttgttg
    43741 ggtcttacat aaataaaata ttgccaggtt ctagtaacaa tatattaaac aatataaatc
    43801 ctgctgtaga gtattataat ctaaatataa gcataaaaga tacagtgata caaaatttaa
    43861 aatcagatgc aatctttatg ggctcaatag ctctattaag tctatttgta gtaacaattc
    43921 cagcagtgtt ggtagctttt gtattaaaag ggatgtcaat tggttataca ataaatagtt
    43981 gtatattggc attaaaattt aaaagtataa aaatgatttt aataatatta tttaaaaatt
    44041 tgattattat tccatgtgca atcatattag cattaattag tttaagttat tttaaagaaa
    44101 tggtttatga atttaaaaag aaaaatagaa aaaatatgca atttttaatt aagaggtata
    44161 tactaaatat tataattata atagcactat cattggggtt gcaattaata ttaaatactg
    44221 caagtattgg tattattaag ttcctagcta aataaaggag tttataatgg atattataga
    44281 gggatatata gattacataa aagataaaaa aaaattatca gagaatacag tggcatcata
    44341 ctttatggat ataaaaaaat atatggaata tataaatcaa aaaagcatta aactagtaga
    44401 tatagtagaa aatgatatta taagttactt aataaagttg gaaaaagata atgtatcaat
    44461 agctacaata gcgaggatga tatcctctat aaaatctttt catgattatt tatttttaaa
    44521 tcatatatgt acaaataatc ctgcaaagga tataaaaaaa cctaaaataa aaaaagaaaa
    44581 tataaatata cttacagaag aagaaattga aagactatta aattttccaa agttaacaac
    44641 acctaaattg attagggaca aggctatttt tgaagtatta tatggtactg gtataaaagt
    44701 atctgaatta gtagagatga atatagagga tattgaccta gatattgatt atatatattg
    44761 taattcatgt tgtaaaaatc aaagagtgat accactttgt gatattacaa aactttactt
    44821 agaaaagtat ctaaaagaag caagacctaa aatggctgta gaaggtgaaa aatcattatt
    44881 cgtaagttca ttaggtcaaa ggtttacacg acaaggtctt tggaaagtca taaaaaaata
    44941 ttctaatcta gccaatatag ataaaaatat aaatcctaca atgcttagac attcatttgc
    45001 tattcatttg ttaaatgaag gtgctaacat tgctgttgta agtaaaattt taggaaatgt
    45061 taatttatct agtttgcaag tatatttaaa tcatatagat aaaaacgtga gaagagaaat
    45121 aaaggagaaa catcctagaa atgatgttga tgtagaatta caaaaagcag aagctaaata
    45181 gactatatag caaattttat aatttagaag gagcatattt atatgagcag agtaatttgg
    45241 attgtaattg atagtgttgg gataggagca ttgcctgatg ctgaaaaatt tggtgatagt
    45301 aaggatgtaa gtacccttgg aaatatattt aaggaatatc cagatattca gattcctaat
    45361 atgagaaatt taggtatagg aaacatagat ggtatagatt tttttgaaag tataaaagaa
    45421 ccaataggtt gttttggaaa gtgtaaggaa atgtctcagg gaaaagatac tactacaggt
    45481 cattgggaaa tgactggtat aatagttgac aaaccattta agacatttga acatggattc
    45541 tctaaggaga taatagaaga gtttgagaaa aaaactggaa gaaaagtagt aggaaataaa
    45601 ccagcttcag gaactgtaat aatagatgag tatggagaac atcaaataaa aactggagat
    45661 gtaatagtat atacatcagc tgatagtgta tttcagattg ctgctaatga agaagtaatt
    45721 cccctagaag aactctataa tatgtgcaaa atcgctaggg aaataatgat gggggataat
    45781 gcagtagcta gagtaattgc tagaccattc ataggtaaga aaaaaggtga gtttgtgagg
    45841 acttcaaata gaagagatta ttcactagac ccatttgaac caacagttct tgataatata
    45901 aaagaatcag gacttgatgt tttagcagtt ggaaaaatag aagatatttt taatggaaaa
    45961 ggaattacag atgctatcca cactaaaagc aatatggatg gagtggatga aactttaaat
    46021 tatatgaaac aagataataa aggtctaata tattcaaatc tcgttgattt tgattctaaa
    46081 tatggtcata ggagagaccc agaaggatat aagaaagctc ttgaagagtt tgatagtaga
    46141 cttcctgaaa taatggctaa tatgagagaa gatgatattt taataatcaa tgcagaccat
    46201 ggaaatgacc caacatataa aggtacagac catacaagag aatatatacc tgttatgatt
    46261 tatggcaata agattaaaaa aggttttaat ttaggagtaa aagatacttt tgctgatatt
    46321 ggagcaactg ttgcagatat actaaatgta aagttgccta aacatgggtc aagctttaaa
    46381 gaagatttat tttaaactat aaaatgataa aaacttagct taataggatg gagagattgg
    46441 aatgtttgaa aagatagcac aaagtagtaa atttataaat tctaaaagtg atataaaacc
    46501 taagattggt ttgatattag gttctggact aggtgattta gcaaatgata tagaagaccc
    46561 tgtcgcaatt aaatatagtg aaattccaaa cttccctgta tcaacagtag caggacatgc
    46621 tggacaactt gtaattggaa aacttgaagg aaaagaagtt attgctatgc aaggtagatt
    46681 tcattactat gaaggatatt ctcagaaaga agctactttt ccagtaaggg ttatgaaaga
    46741 attaggagtc gagattctta tagtaactaa cgctgctgga ggcgtaaata aagaatttaa
    46801 agcaggagat ttgatgctta taagagacca tataaacttt agtggaagta atccattagt
    46861 aggaaaaaat gatgacagat ttggtgctag atttccagat atgtcagatg catattcttc
    46921 taaatatgta gatgtagtta aaaactgcgc taaagaatgc aatatagatg tcaaagaagg
    46981 cgtttatatg ttttttagtg gtccaaacta tgaaacacca gcagaagtga gaatggcaca
    47041 aattttggga gctgatgctg taggtatgtc tactgttcca gaagtcatag tagcttctca
    47101 ctctaatata ggagttattg gtatatcttg tataacaaat atggctgctg gcatcttaaa
    47161 tcaaccacta agtcatgagg aagtaataga aactactcaa aaagttaaat cagaatttat
    47221 gaatttagtt aaaacaacgg ttaaaaattt ataagttaaa gcttattata gattttttga
    47281 ggaagtttat aataaaatag ttaatgttta atttgaaaag aattaataaa aagctgtctt
    47341 gatatagaaa gttatttcta ataaaggaca gtttttttat aatactacaa catttgaaag
    47401 tgttttaaag tttaatattt atttaaatta ttataggtta gaatggagat ttcaattatg
    47461 agaatgtatg atattataaa aaaaaagaga gataacctag agcttagtaa aaaagagata
    47521 aactacttta tagaaaacta ttcaaaggga gatatacctg actatcaagc ttctgcacta
    47581 ttaatgtcga tttatttaaa taagatgaat aaacaggaaa ctgtacatct tacagaagca
    47641 atgatgaact ctggagacat gataaaccta tctgagatag atggaataaa ggtagataag
    47701 catagtactg gtggtgttgg agataagact accatagctc ttataccttt ggttgcttca
    47761 tgtggagcac cagttgcaaa gatgtcaggt agaggtcttg gtcatactgg tggtactatt
    47821 gataaattgg agtctatacc aggtttttcg acagaaatgg agataagtaa atttattgat
    47881 tctgtaaata agtctaaaat agcagtttgt ggtcaaagtg caaaggtagc aattgcagat
    47941 aagaaaatat atgctcttag agatgttaca gcaactgttg ataatatatc attgatatca
    48001 tcaagtgtaa tgtctaagaa gttagcttca ggagctgatg caattgtgct agatgtaaaa
    48061 actggtgatg gagcatttat gaagacatta gaagagtctt ttgagttagc taaatctatg
    48121 gttgatatag gtactggtat gaatagagat acaataggga ttgtaacaga tatggatgaa
    48181 cctttaggtt ttgcagtggg aaactcttta gaagttatag aagcaattga gacattaaaa
    48241 ggaaatggac ctaaagacct tgttgagcta tgcgaagtat taggagcata tatgttggtt
    48301 ttatcaaagg tagcacatga ttttgaagat ggtgttgaaa aaataagaga atcaataaaa
    48361 tctggtactg ctatacaaaa actcaaagag tttatagaga atcaaggtgg taataaagat
    48421 gtagtagatg attattcttt attcaaaaaa tcaaagtata aatatccagt taaatcaact
    48481 aaatcaggtt atataagcaa aattaaagct gaagatgttg gtgtatcggc tatgattctt
    48541 ggagcaggta gagaaactaa agatgatatt ttagatttat cagcagggat aattttagaa
    48601 aagaaagtag gagattatgt aaatgaaggt gaagttttag cttacatgta ttataatgat
    48661 gaacaaaagc tttcattggc aaagggaaga tttattgatt cctactctat tgtagattca
    48721 aaaatagaaa aaaataaatt aatatatggt attgtaacta aagaagagat taaaaagttt
    48781 tagaaaattt tagaaaagtg attataaaag gcctaacatg tcaaaaataa tgttaggttt
    48841 tttatttttt gatagactat aaattatacc aaaaatatat attttaaaac attttttaca
    48901 atataaataa gtttattcta caagatgatt gaaaattaaa gtatctagtt ttataataga
    48961 aaatggataa atatacataa ggagtagatt atattatgaa ctttaaagaa aatagattga
    49021 aaatagcagt attaataatt gttattttga ttatcttagc aggtatattt gtgtttatac
    49081 aaataggtcc ttatgataaa aataacaaaa aagatgtaat tatcgacgtt ccaagtggag
    49141 catctgttgg aaaaatatct gacatattat atgaaaataa attaataaag aatgaactat
    49201 tatttaaact tttggtaaag gttagcaata aagctccgtc tataaaatca ggaacatact
    49261 tacttaatca atcgtattca aacaatgata taataagtct tttagtttca ggtaaaatat
    49321 atcaggatgg tataaaagtg actattccag agggagctac atctaaagaa attatagcaa
    49381 tgttagtaag taaaaattta ggagataaag ctacttttga aaatttaata aaaaaacctc
    49441 aagaatttta tgataaattt ccatatttga aggaagatgg aataacctct ttagaagggt
    49501 tcttgtatcc agaaacttat tattttaatt caaagaaaca atcagaagaa gatattttaa
    49561 gcgaaatgtt aaaagtattt gacagtaaat acacggacaa gtttaaaaag aaacaaaaag
    49621 aattaaatat gactcttcaa gaagtaatgg aaatggcatc aataattgag aaagaagctg
    49681 ttcttgacaa agacagacct ataatagcaa gtgtgtttta taatagactt aaggtaggta
    49741 tgcctcttca atcagatgct acaatacaat atatatttga agagagaaag aaaattgtaa
    49801 catatgatga tttaaaaatt gattcaccat ataatagtta taaaaataag ggattacctc
    49861 ctacaccaat atcaaatcct ggtataaaat ctattgaagc agcattatat ccagagaaaa
    49921 cagactattt atattttgta gctaagattg atggtggaaa taattatagt acaaactatc
    49981 aagaccattt aaaatacgtt aaagaatata aagaagcaag ggataaacaa tcaaaagata
    50041 caaaagcaac aaataaagaa aatacaaaaa aataaaccat gattataaaa agtctaacag
    50101 ggtaagaata atgttgggct tttttattga aaattgttat tcttagattt ataataaaga
    50161 aagtgtaaat atatataaca atatgaattt aaaaaataat aaattaatat aaaacttgaa
    50221 tatttattat tttagggagt gtttttatga gtaatatagt taatgatttg gttgaagatt
    50281 atataagagt gacattaaaa gaaaaagaag gatttttaaa agatttagaa atttatgcag
    50341 aggaaaatag tgttcctata atacataaag aagtttcaga tttattaaaa gtcttgttaa
    50401 aggttcaaaa accaaagaga attttagaag taggatgtgc aattggttat tcttctattt
    50461 tttttgcaac tattatagga aaagatgcag atataataac tgttgagaga aatgaaaaaa
    50521 tgatagaaaa agcaaaagaa aacataaaat tagctggatt tgacaataac ataactatac
    50581 tagaaggaga tgcagaagaa aaacttagtc aagtccaagg tgaatttgac cttatattta
    50641 tagatgcagc caaaggtcaa tataagctat tttttgattt agttatagat aaattaaaag
    50701 atgggggact tttagtatct gataatattt tgtataaagg tatggttgct catgatgatt
    50761 ttgttgtaag aagaaaaaag actatagtta aaagaatgag aaattattta gattatatat
    50821 gtaattgtga ctatttaagc acatcattgg taccaatagg tgatggtgta gcactaagtt
    50881 ataaagaaag taaaagaggt gatgtagatg gaattaaata aagtagaact tttagctcca
    50941 gctggtgatt tggagagatt gaaaatagct ataacatatg gagcagatgc cgtttatata
    51001 ggtggagaaa tttttggaat gaggtctgca gcgaagaatt ttagtaagga agatatggca
    51061 gagggagtag cttttgcaca tgaaagaggc aagaaagtat tcgtaacagt aaatataata
    51121 cctcataatg aagattttct acaattagaa gactatttgt tggaactaga agagatagga
    51181 atagatgcag ttataatagc tgacccagga gtgcttagtg tcattaaaaa agtaattccg
    51241 aatatggaaa tacatttaag tacacaagca aatacaacca attatctaag tgcaaacttc
    51301 tggtacgagc atggaataaa aagagttgta gtggcaagag aattatcttt tgatgaaata
    51361 tctgagataa gagcaaaaac acctttagat atggatatag aagcgtttat gcatggtgct
    51421 atgtgtattt cttattctgg cagatgttta ataagcaact atatgactgg aagagatgca
    51481 aacaaaggtt cttgtgctca atcttgtaga tggcaatatc atttggtgga agaaaaaaga
    51541 cctggtgagt attttccaat atacgaagat gaaaggggta cattcttctt taactcaaaa
    51601 gatttatgta tgatagagta tataccagag ttaatcaaat ctggtataac aagtttaaaa
    51661 atagaaggta gaatgaagac tgcatactat gtagctactg ttgtaagagc atacagaatg
    51721 gcaatagatg aattttacag agacccagaa aactggaagt tcaatccaat gtggatggaa
    51781 gaactaaaaa aaggtagtca tagacatttt acatcaggtt tttacttgaa taaaccaaca
    51841 acagaagacc aaaattatca atcagcatca tatgttagaa actatgattt tataggtata
    51901 gttagagaaa cagaagatga agatggtctt attgttgttg agcaaagaaa taaaatgtgt
    51961 gttggtgatg aaatagaagt tatgggacca tataaagaaa ctatgtttac taaaattgaa
    52021 gaaatgtaca atgaagaagg agaagctata gaatcagctc ctcatcctag acaaatagtg
    52081 aagttaaagc tatcagtaaa agttggtaaa gattatatgc ttagaaaagt tatagaagaa
    52141 aaggttgaag aataataaaa aattgataaa aatagtatta gccccttaga aattgtcaat
    52201 aatgaaatta tctaaggggt gatttcatgt caaaaaagaa gactccattt ttgaaaaaag
    52261 tgggaaagag aagctggtgt atatttacta taattttaat aatttatagt gttttaattt
    52321 ataggctagt tgatatacaa gtattaaaag gtgataaata caaacaaagt gttgaatcac
    52381 aaagcgttga gaaagtcgag ttaaatagtg gaagaggaat aatctatgat agaaacaaca
    52441 agaagcttac agatacaagt aaatctcagg tattaattgt tgaaaaagaa aaattaaata
    52501 ataactataa aattttggag cttattaaga aagctactaa gatgaatgat ttagatatat
    52561 ataaagctgt acaagagcaa ttgacacgcc ctataataca gattcagact aaaaatatcg
    52621 ataagagtat gaaaaaagaa cttgagaaaa atggaataat ggtagaagaa aaaactatga
    52681 ggtacgcaaa agatggttta ttatcacata caataggata tataaaagaa gatgataaat
    52741 caggtcaatc aggaattgaa aagagtatgg atagtgtact tagaaattca aatgaaaagt
    52801 atataagtgc ttttaaagct ggagatgcag gaaatgaaaa atctctaaac atactaaagg
    52861 gaagtgtaaa aactgttgat aataaggata aagatagaca tctaaaaact actattgatt
    52921 ataacattca aaaaaaatta gaacaaatac taaataaaga agaaaatcct acagcagcaa
    52981 taatctcgga agcatctaca ggtgaaattc ttgcaatgtg ctctagacct aattttgacc
    53041 aaaatgacat atcaaaaagt ttaaaaggaa aaaatggaga atttgaaaat agagttataa
    53101 aagcgacata tccaccaggg tctgtattta agatggtagt tttattttct gcacttgaaa
    53161 atggtgttat agatgagaac tatacttaca actgtacagg taagactaaa gttgggaata
    53221 ctaatgaaat actgcgatgt aataaaagag atggtcatgg tttccaaaac ttaagacaag
    53281 ctttttctaa ttcatgcaat cctgcatttt tagatatagc tatgaaactt ggaaaagaaa
    53341 agatactcaa atctgctgaa aaattacatt tatttgaaaa ggttgatatt ggtcttgatg
    53401 aagaaaaaat tagagaagct ccaaaaaaca tatcaataag aaatttagct ataggtcaag
    53461 aaaatataga atttacacca cttcaaataa atcaaatgac tcaaataata gctaataatg
    53521 gaacattcaa accactatac ttatataaaa gtcttgtgga caataatatg aatacaataa
    53581 aaacttataa gtcttcaaaa aaagaagaac ttatttctcc ttatgtgtgt acacaagtta
    53641 aagaatatat gaagtctgta tctaggattg gtacagctaa agacctaaaa gatattgaag
    53701 gtggttgtgg agttaaaact ggtacagctc aaagtagttt aaataaaaaa gctatagacc
    53761 atggatggat aacaggattt tatcctgaag aaagacctaa gtatgtaata actgtgttag
    53821 tagaaggaac tcaaaaagga aataaatctg caacacctat atttaaggaa atatgtgaaa
    53881 gtataaaata aattatgtac tataaaattt aaggatatat cgtaactttg attttagata
    53941 gaaaattttg tctaatgatg tacgatatat ccttttaaaa tatagtatta actttcttga
    54001 acaagctctt tttctagttt tttaagagct tttttttcga ttctagatac atatgacctt
    54061 gatatatcga gtttttgtgc aatttctctt tgtgtcttat agccataagg agttaaccca
    54121 tatcttaact ggacaatttc tctttctcta ggagtaagaa ttttgtttag ttgttcgtaa
    54181 agttttccaa cttgaacttt tagttcaact tcatcaagaa catagttagc ctctgtacca
    54241 agtatatcta aaagacttat ttcattacct tctttatctg ttccgatagg gtcttgtaga
    54301 gatacttgag ttttattttt tttgttagat ctaatattca ttaaaatctc attttcaata
    54361 catctagaag catatgttgc taatcgagtt cctttatcta tgttataagt ttctatagct
    54421 ttaattaatc ctattgtacc tatggatatt aaatcatcct gatcttccgt tgaattatta
    54481 tatttctttg ctatataagc tactaatctc atgtttcttt caattaatgt atcttttgca
    54541 cttttatcgt tttctatttt aaatttagtt aaatactcaa tctcttcttc aggggttaag
    54601 ggtttttcaa aagatttaag agctgccaat aggtcacccc cttttcaacg gtcactttaa
    54661 attatatgaa ggagacttat ccaagttgac tgttatctaa taaaataata tgcatatttt
    54721 tagaatttaa aacatatatt tgcaaacttt tgaatggaat atgacataaa gagtgggaat
    54781 ttaaatttaa gtttttgttg tatatatatg aaacaaggcg aagaaattat tgatttataa
    54841 agtataaatt ggaattgagg tgtcaataaa tataaaagga aatagtattt atatatgttt
    54901 tggtgttgaa gtaaaagatt aatgcaaagc attagagtct ataaaaatat gaatatagga
    54961 ggtgtaattt tacaatactt aaaaaagtaa atgtaattaa ttgtttgtat aaagttgatt
    55021 acaagcaaaa gtatcagtca tagttaatac tgttaaggat gaaggtggtg tgttaattta
    55081 tatatgtatg ggaagaaatt ttgattacaa tgaaaaaact tacaaaagat atttacgaaa
    55141 aaacttatag ttaaatgttt atatataaaa tattatttag gggttgtttt tattattgaa
    55201 aataagaaag agtggtttta tatcaattga atgtataata agtattgcta tattatatgt
    55261 ggctgtttat ttagtttcta catcattgta taattgttat agttttatca gtagaaatat
    55321 atctgacaga gaaatgttaa gtacagcaaa aaaatatata gaagatgaga agtatagaat
    55381 acaaaatagt aagtatgagt taattgaaga taagatagaa aaaaattaca taaatggata
    55441 tgaaattaac agtagaatag agcaaatttt agattattat caatgctatg aaataaatat
    55501 agagataaaa aatgaattta aaaaactgag gtttaatagc tatgttacta gaaaataaag
    55561 gctctatatt aataataaca ttgataatat tttctattat aagtactgtg tgcattatgt
    55621 gtataggttt aatttataca cataataata tgtttgagtt aggatacaaa gacattcaac
    55681 taaaagaaat ttctttaagt ggaatagaaa tatcagtaag taatgtactt tcttgtgttg
    55741 aggaagctat tgatatatct aataatgaag acgaatttag agaatatttc ttaggaaata
    55801 atatgattga atgtataaaa aaaataaaag atacatctta tagtagttta gaagaacttt
    55861 ctttaaaagt agaaaataat actatttatg acagaggaga tttttttgaa tttgatatag
    55921 aaagtaatgt tagagaaaaa gaatttttaa aagcaataaa agtaagagtg aaaatcaaaa
    55981 atccatggat aggaattgat attgaagatt atatggataa atctaataac aataaaattg
    56041 atgacaaaac attcaataat tataaagcat ctgaaaataa tgaaattata aatcaattta
    56101 aaaatgaaag tgaaaatata aggaatcaag aggttgttga atttacagaa gaagatgaag
    56161 aagaacttaa acaaaacata attgaaaata taaagaagaa ttttgatgaa aaaaacctag
    56221 tacaggtata taagtatagg ggtgtataac tttgaaaaaa gaaggaatgt gactgtaata
    56281 gaattaatag tatctatcag tataatactc ttgatagtta cattatcttt tccaaaagat
    56341 aatcttgaaa atcataaaat aaatttattt gcacgtcaac tttgttcaga tataaggtat
    56401 gttaggcgaa ttaatatgtt tagcaactac aatacatata tatattatat aaatcaaggt
    56461 aaacacgaag gttatgtatt gagaaaagat ggtaaaaaca ttaaatcaat aatgctacct
    56521 aaaaatgcaa aaatagctag gagtattgaa ataataaagt ttaaatctga tgggtcgcct
    56581 caaaaggcgt ctacaataga ggtatataat aatagattaa gaaaaactat aacaataaca
    56641 cctgtaagtg gaagagtact tctgaaagag ggaaaatatg aaacataaat atggttactt
    56701 gcttttggaa agtgtcgtat cattgtcttc aatggtgata attatactag ttttatattc
    56761 tatatttttg tctacaataa acttaaagtt aaaagtagaa gataagatag aactacaaca
    56821 acaaagtctt gaaatcataa aatctatgga aggaattatt agcaattcta tgggaataat
    56881 gaatgtatct aattatgaag aaacatttaa aaagacaaca tctataaaat gtagatattt
    56941 agatgaaaat aataatgaag aaggcataag taataaagaa attatattga atgaaagacg
    57001 aaataagtta tttgtaaatt ctttaaatgg cgaaagtagt caagcaggtg gttatgaaat
    57061 tggagattat gtagatgaaa tgtatgtatc aattactaat aatggtcaat acgttaatat
    57121 taaattgaaa ttatcaaaat gtagtcaaaa atatgagact gatttcaaaa taaaagtatg
    57181 gaattttagt gaaagtatat aaaaatacat aaatttaaga gaaagaaatg acatcaataa
    57241 gtcatataaa atataattat tgagaactat ataactaaat aatatcaata tgtaaagtgt
    57301 atagattaag aatatagagg ataataataa aaatatagaa taagtaattt gccaaatact
    57361 tgtttatatt gtataactta tgatattatg atattagtaa aaatttgtaa tcctgacttg
    57421 acagaattca agtaagagat ataattttaa aggcatagta atgtaaaatt tactaaaaaa
    57481 taagaaattt attttaatat ggaggaacaa aaaatggtat cagcaggtga ttttagaaaa
    57541 ggtgttacat ttgaaaaaga tggacaacca tgtttagtag ttgattttca acacgttaag
    57601 ccaggtaaag gagctgcttt cgttagaact aaatacaaaa acttaaaaac aggagctata
    57661 agagaagaaa gtttcaatcc aagtgaaaaa ttccctaaag ctgttataga tacaagacaa
    57721 atgcaatatc tatacaatga tggtgagtta tattatttta tggatcaaga aaattttgaa
    57781 caaataccat taaactatga gcaagttgaa gatgcaatta agttcttaaa agaaaatgaa
    57841 gttgctacaa taagatttta ccaaggacaa ccattccaag tggaagcgcc aaactttgca
    57901 gagctagaag ttacagatac agagccaggc ataaaaggtg atacagcaag taatgtaact
    57961 aaagcagcta cagttgaaac tggagcagtt gttcaagttc cattatttat aaatactgga
    58021 gataaagtaa agatagatac tagaacaggt gaatatttat caagagtata aaaatttatg
    58081 tatataaaag cttatatgtc ttaataatat aagatatatg agcttttagt ttatatataa
    58141 aaaagaaagc gaggggtgtt acatgaaaca tttatatgaa gaagttgcat acttaaaagg
    58201 cctagcagaa ggactagaaa taagtgctga aagtaaagaa gggaaaatga tacataaaat
    58261 agttgatgca ttagaagtat ttgcagatgc tattgtaaca ttggatgaag aacaagaaga
    58321 acttcaagat tttgttgaat ctatagatga agatttagca gatttagaag aagatattgc
    58381 tgacatggaa gaagatcttt atgaagaaga tgacgatgag gatgatgagg acttcagcta
    58441 tatagaaatg gaatgcccaa attgtggaga gttagtagaa atagacgaag atttgttata
    58501 tgatgatgaa gtagatgttg tttgtcctga ttgtaaggct gtgatattat catcagaaga
    58561 tgattgtgat gatgattgta catgtggtgg ttgttcaagt tgtgatgata gagagtaaaa
    58621 attcataaga attaaaactg cctatgatgc ctatgagata ttttgcttca taggtagttt
    58681 tatttttatg aggaagggta ttatgtattt tggttttgca atacttggac aaaaatagta
    58741 cactagaatt tatagaatag gattttggag ggatgtaaat atgaaaataa gtaaaaaatt
    58801 actagataat atacaaagat ttgaaaatgt tataaattat aaatttaaaa ataaagaata
    58861 tatactagaa gctcttactc atagttcata ttctaatgaa aataaaaaat ataattttaa
    58921 cgaaagattg gaatttttag gggattcggt tttaggcata gtgataagtg attatttatt
    58981 taatgaagaa gctaatctgc ccgaagggga actaactaaa cttagagcaa atatagtctg
    59041 tgaagattca ttaagtgaag tagctaatga tataaattta ggtattcaca tgttattagg
    59101 tagaggagaa gaagcaacag gaggaagaca taggacttca atattagcag acgcatttga
    59161 agctgtaata gctgctatat atcttgatgg aggttttgaa agtgcaagac agtttatact
    59221 tcatcatatg gaaaatataa tttatgattc aagaaaagga aatatattta gagactacaa
    59281 aacgcatctt caagaggtgt tacaagggaa tggagaaaat aatatctggt acaggcttat
    59341 agaagaaaaa ggaccagacc ataataaaag atttgtaatg gaagttggaa ttaatgacga
    59401 tgtacttggt ataggagaag gcaagagtaa aaaagaagct gaacagttag ctgctaaaat
    59461 agctttaaag aaaaaattat gggaaaaata aatataatat gtaaaaatat aaaaagaaat
    59521 atttatatta gaaggatgtt gtagatgaaa aagagaatta tacctatatt tgttcctcac
    59581 aaaggatgtc ctcatgattg catattttgt aatcaaaaaa aaataacagg tgtgagtact
    59641 gatgttacta gtgaagatgc aagaaatata attgaggaat gtttagagac tatagataaa
    59701 gatgcagatg tagaaatagc attttttggt ggtagcttta ctgctataga tattgatata
    59761 caaaaaagtt tattatcagt tgctaaagaa tatgtagaaa aaggtcttgt aaaagatatt
    59821 agaatgtcta caagaccaga ttgtattgat gaagatatat taagtatgtt aaaagaatat
    59881 aagacaagta taattgaact aggagtacaa tccttagatg aaaaagtatt attagatagt
    59941 ataagaggtc atcaatctga aattgtatac aagagttcaa agatgataaa aaatagtgga
    60001 atcaaacttg gattacagat gatgattggt cttccagctg acacagaaga aaagtgtata
    60061 tttacagcaa aaaaatttgt agagctaaaa ccagattgtg ttagagtcta tccaactttg
    60121 gtagtaaaag atacaggtct tgaaaagtta atggaacaaa ataaatataa tccatttacc
    60181 cttgaagaga gtgtaaatat agtaaaaaaa gttcttgtac tgttttatgt taataatatc
    60241 aatgtaataa gagttgggct tcaagctact gatgatatac aaattggaaa agctgtttta
    60301 gcaggaccat atcatcctgc atttagagag ttggtagaag cagatatgat aaaagattat
    60361 ttagaatttg ttattttgca aaataaaaat ataaagcaaa tgttggtcaa atctaataaa
    60421 aagaatattt ctaaaatcat aggaaataaa aaaacaaatg ttaaatatat ggaagaaaaa
    60481 tttggtgtgc ttttaaaaac acaagaatca gatttagata taaatcaatt agaaattgtg
    60541 ttagatggga aaagtttaat tagtgctaat atgagagaca ttcatagaaa attgtatgac
    60601 atttatgacc tttagtttta ataatgaagg gagagaaaag atttgtattt aaaaagacta
    60661 gagttaaagg gatttaaatc ctttccagta aaaacagata ttatttttaa agaaggaata
    60721 acagccatag taggaccaaa tgggagtgga aaaagtaata tatctgatgc tgtaagatgg
    60781 gtattaggag aacagagtat taagagtctt agaggtgata aactcgaaga tgtaatattt
    60841 gcaggtacag atacaaaaaa acctatgaat tattgtgaag tggctcttac tattgataat
    60901 tctgaaaatc aattggaatt agattttaca gaagtaacta taagaagaag ggcttataga
    60961 aatggtgaaa gtgaattttt tctaaataat aaaagttgta gattaaaaga tataaaagaa
    61021 gtctttttag atactggtat tggaaaagat ggttattcaa tcatagaaca aggaaaagta
    61081 gatgaaatat taagtaataa tcctttaagc agaagaaaag tttttgatga agcttgtggc
    61141 atatcaaaat atagatataa aaaacaggaa gcagaaagga atttaagtaa tacaaaggaa
    61201 aatttagaaa gaatagatga tgtatatata gaaattgaaa atcaattaaa gcctcttttt
    61261 aatcaacaga caaaggcaaa aaagtacttg gaaataagtg aaaaattaaa gacacttgaa
    61321 gtaaatagct ttataagaga aattgaagga atagaaaaag aattaagtga ggttaatgaa
    61381 catcgtaagg ttattgaaaa ggagctcaat gaaaaagaag aacaaaaaaa tgttgtagag
    61441 aaaaagcaag aagatattaa taaagaggta gaggtattac aagatgtaat tgaaaaatct
    61501 gtagattata taaattcaat taaaggagtt atatcaaaaa aagagtccca aataaattta
    61561 attaaggaaa gaataagaaa ttttacgaat gaaattagta gaaaaaattt agaaataaat
    61621 gatataaaag agaagctaaa tgaaaataag caatacataa aagaattaga aagcaataaa
    61681 ttatcaggta gtgaagaact atctaccttg caggaaaata taaaagtatt ggaagcaagt
    61741 aaagataaac aaaaaattaa gttagaatcc ctaaataatg agatagaatt attgaaagaa
    61801 agtataattg atatattaaa taaaaaacaa gagtttagta ataagctgtc cactttaaac
    61861 gcaaataaag aaaatatgaa tatcagagat gaaaatataa attcagagat aacagagtta
    61921 aacaaaaata ttgaaataaa atcatctgaa ttagatacta taaataaaga atttaatatg
    61981 caaaatgaaa atttaaagaa tgtaaataat agacataaag aattatcaac taatttgcag
    62041 gattcaatta gtgaacacaa taaactagaa gatgaaatac agaaaagtaa atataattta
    62101 aatggatata attcaaagtt aaatgtctat atagatatgg aaaatcatta tgaaggattt
    62161 aatagaggag taaaagaagt actaaaaaat aaaaatttaa aaggagttca tggagcatta
    62221 ggacagatta taaatgtacc tgaaaaatat gagaaatcta tagaagcagc tcttggtgct
    62281 tatatgcaaa atataataac tgataatgag tttagtgcta agtctgcaat aaactatcta
    62341 aaacagaata atttaggtag agtaacattt cttccattaa atataattaa atcaaataaa
    62401 ataagtctag gaaatttaaa agcaaatact aagttcatag gaatagcaag tgatttaatt
    62461 acatttgatg aaaagtatag aaatataatt gaaaatatac ttggaagaac aatacttata
    62521 aataatatag atgagggcat aaaatttgca aaagaaactg gtcataggtt taaaatagta
    62581 actttagatg gtgaaatctt aaatccagga ggttctttga ctgggggaag tctaaaaact
    62641 aatgggaata tactatccag aaaaagatac attaatgaat atacagaaaa gataagtaat
    62701 atcaagaatg aaatttcaca tctagaatta aaaagagaat ctttagacaa agatgtgaaa
    62761 aatatcaaaa atgaaattga ttcacatgaa agtaaaataa aagatttaga aaaaagtata
    62821 ataataaaaa gtacaagtat aaagaatgtt gagtctgaaa ttgaatcgtt aaaaggtagt
    62881 attactaaat tagaaaatga gaagaatgat ttaaattcta acctaaatta tacacttgaa
    62941 aaaagtgatg atgttagaaa agatatggaa gagttagatg atttatacaa taaaaataaa
    63001 gaaaaaattg atgcattgaa tgaggaaata aaaagataca atgatttata tgataaagaa
    63061 aaatctgaat ttgatgaatt gaacttaagt ttagtgaaga aaacagaagt ttacaatagt
    63121 atagttagag atataaaaag aatatctggt gaaaattgtg agctagaaga aaaaaataaa
    63181 caattagaag agtcattaaa ttatgaagaa catgaaataa ttaaattaca agattctata
    63241 ctcactgaag aaaaagaaaa agaaaattta acaaaacaac taggggatag taatagaaat
    63301 cttgaaacta gaaaaatagc aaaagatgat ttaaaaaata gttttgatga aattaataaa
    63361 gaattaaaaa ctatagatag acagcatata gaacttaaag aaagtttatt taaagttggt
    63421 ggaagattag aaagattaaa aactagtcaa gacacatata taaataagtt gtttgagcaa
    63481 tatgatatga ccttagtaca agcattggaa attaaagatg aagatttgga tatagataga
    63541 aaattcttag aaagtctaaa gagagaaata agaagtcttg gaaatataaa tatagactct
    63601 ataaaggaat atgaggaaat aaaagaaaga tacgattttt atagcgaaca aaagcaagat
    63661 ttagaagagt ctatggaaga gatagaaaaa cttatacata ctttagaaga aaatatgaaa
    63721 tctgaatttg aaattaagtt tgaagaaata agtaaaaatt ttaaatatgt atataagaga
    63781 ttatttggtg gaggttgtgg agaattaact attttagata aagaaaattt attagaaagt
    63841 gatatactaa taacagctca acccccaggt aaaaaaatga aaaatttaaa cctattatct
    63901 ggtggagaga aagctttaac ggcaataagt atattatttg ctatattgat tacaaagcca
    63961 acaccatttt gtatattaga tgagattgaa gcgccacttg atgacgcaaa tatatttaga
    64021 tttggagaat ttttgaagga tttatctaaa gagactcaat ttatatcagt aactcatagg
    64081 agaggaacta tggaagctgc tgattatatc tacggagtta caatgcaaga aaaagccatt
    64141 tcaaaagtta ttagtttaaa attaaaagaa gctcaggaaa taacagatat tatataactt
    64201 agattgacat aggaggaata acagtgttaa aaaaattatt tggttttgga aaagacaagg
    64261 aaaaggaaat agaaaaaaaa gatgctgaag aagaaataga agttgaagac agtgttgata
    64321 atttagaaaa cttggaagaa actatttttt caggacttga agaagaagtg atagataaag
    64381 tggaagatgt tgaagaaaaa aatgaggaaa gtgtcaataa tgaaggcact gaagaaatcg
    64441 aaaactttga aaaaatagaa gttgagatgg atagtaatgg aaaagaagta gaaaatattt
    64501 caaataatga ttctcaagaa gagataatcg aagaattaga aaattatgat gaaattgagt
    64561 ctaaagagat agaagataaa gaagataaga aagttaactt gtttgaaaga ctaaaacaag
    64621 gattgacaaa agcaaagcaa ggaataactg atagaataga tgaagtttta aaatcatata
    64681 caaagataga tgaagaatta cttgaagatt tagaggaaat tttaataaca gcagatgttg
    64741 gtgtaaatac aactatggat ataattgaaa gactaagaga taaaataaag caaaaaggta
    64801 ttactgaacc aataaaggta agagaagaac ttaaatctat agttgaagat attcttacaa
    64861 atgaaaactc tacactagat atagaaccag taccatgtat aatattaatg gtgggtgtaa
    64921 atggggtcgg taagactact acaataggta aactagcaaa tagatacaaa aaagatggta
    64981 aaaaagtttt attagcagca gcagatacat ttagagcagc agcaacagag caattagaaa
    65041 tttgggcaaa tagaaccaat gtagacataa taaaacatca agagggagca gaccctggag
    65101 ctgtagtatt tgatgctata aaagctgcaa aagctagaaa aacagatgta ttaatatgtg
    65161 atacagcagg aagattacac aataaggcta atcttatgaa tgaacttgga aaagtattta
    65221 aaatagtaga tagagaattt ccagaagcaa aacgagaagt acttcttgtg gtggatgcta
    65281 caacaggtca aaatgcagtt gttcaagcaa agacatttaa agaagttgca gatataacag
    65341 gtatagtact tacaaaactt gatggaactg caaaaggtgg agtagtcctt gcggtaaaat
    65401 cagaagtaga tgtacctgta aaacttattg gagttggaga aagtgtagaa gacctacaag
    65461 atttcaatgc aaaatcattt tcagatgcat tatttggtaa ctaatgttct tttaaaaata
    65521 atggttgaca agagtgttgt tatgatataa aatacaatag tgtaaagtaa ataaccttta
    65581 cagtatactg ctaggaagtg taagatatga atatagaaaa aatggtcgaa attggattgt
    65641 tatttgaaca gtataaagaa ttattaactg acaagcagaa agaaatagtt gctctatact
    65701 atgaagaaga ttattcttta ggtgaaatta gtgaaaatct gaatgtatca agacaaggtg
    65761 tttatgatac cttaaagcgt tcagaaaaaa tactaagaga ttatgaagaa aagttacact
    65821 tagtatcaaa gattcaagag caggaaaaaa atattaagat tataaaagat aaaattattg
    65881 acattaaaga agatttattg cacaatagag attgtgctaa tttaatccct aagctagaaa
    65941 atatagaaga tgtatgtagg gagatgataa aatgatattt gaaggattgt ctgataaact
    66001 acaaggggca tttagtaagt taaaatctaa aggaaaactt acagaagtag atgtaaaaaa
    66061 tgctatgaga gaagttaaac ttgctcttct tgaggcagat gttaacttta aagtagttaa
    66121 agatttcata aaaaaagttc aagagagatg tgttgggcaa gaagttatgc aaagcttaac
    66181 tccagctcag catgtaatca aaattgtaaa tgaagagctt acaagtttaa tgggagatgt
    66241 acaaagtaaa gtaatgattt cctcaaagcc tcctacaatt ttaatgatgg ttggattgca
    66301 aggtgcaggt aagactacta cagcaggaaa acttggagga tattttaaaa agcaaggtaa
    66361 aaaacctcta ttagtagctt gtgatattta tagaccagca gctataaagc aacttcaagt
    66421 tgttggagaa aaattggata tacctgtatt caatatggga gataaagaaa atccagtaaa
    66481 tattgcgaaa gcaggtttaa gccatgcgat taaaaatgct aatgatttag ttattataga
    66541 tacagctggt agacttcata tagatgaagt acttatggat gagttaaagt ctattaaatc
    66601 agaagttaag ccacatgaga tacttttggt tgtagattct atgacaggtc aagatgctgt
    66661 aaatgttgca gaaagcttca atgaggcact tggtgttgat ggagtagtat taactaaatt
    66721 ggatggagat actagaggag gtgctgcact ttcaataaga gcagttacac aaaagcctat
    66781 aaaatttatg gggatgggag aaaagctaga tgatatagaa cctttccacc cagatagaat
    66841 ggcatcaaga atattaggta tgggagatgt cttaagttta atagaaaaag cacaagaaaa
    66901 tatagattta gagaaagcta aagaattaga gcaaaaaatt aaaaaacaag agcttgattt
    66961 tgaagatttc ttacaacaaa tggaacaaat acaaaatatg ggacctcttg acaagatact
    67021 tggtatgata cctggtatgg gaaatgtaaa agaccaactt ggagatgtag atttgaatgg
    67081 caaagaaatg aagagaacaa aagccataat tcagtcaatg actacatatg agagaagaaa
    67141 cccaggagta ttaaatgctt caagaaagaa aagaatagct aaaggcagtg gaactagtgt
    67201 acaagatgta aatagactta taaaacaact taatgaaatg aaaaaaatga tgaagatgtt
    67261 tgctggttca caaaagagta tgaagaaaag gggcggctta ggcggtttac ctttttttaa
    67321 ataaaatata aaaaagtaaa aattattcgg aggtgactgt aatggcagtt aaaataagat
    67381 taaaaagaat gggagctaac aaaaaacctt tctacagaat agtagtagct gattcaagag
    67441 ctccaagaga tggaaaattt atagaagaaa taggatacta taatccaatt tctgaaccta
    67501 aacaagtaag aataaatgat gaaaaagcta taaaatggtt agctactggt gctcagccaa
    67561 cagaagtagt taaaaaatta cttgtaaaaa acggagtaat agaaaaattc gaagcttcta
    67621 aacaagcaaa ataatttttt cttggcaatt agtttaagta agggctcatt gctaaggtta
    67681 ctttaggaga tgaaatatat gaaagagcta gttgtagata tagctaaggc tctagttgat
    67741 aatcctgact cagttgttgt tgaggaattt gaagataatg atggtatcgt cttaaagctt
    67801 acagttgctc aagaggatat gggtaaggtt attgggaagc agggaagaat agctaaagct
    67861 ataagaactg tcgtaagatc tgttgcaaat agagaaaata taaaagtttc tcttgagata
    67921 gtataaaata ggaggattag gtataatgcc tagtcctttt tatataaatg cgtagtttaa
    67981 gattttatga tgatatgacc acataagatt aaatttttta agaaggtgat aacatgaaag
    68041 aaaaattaac tcattttaag gtaggtcaaa tagtaaatac acaaggttta aaaggtgaag
    68101 taagagttta tccgcttact gatgatatag agaggtttga tgaattaaaa gatttctatc
    68161 tgggaaaaga tttaaataat aaattggctg ttgaaaaagt aagatacaaa ggttctatgg
    68221 ttataatgaa gataaaaggc atagacagca tagagaaagc agaaaaacta aaaaataaat
    68281 ttatgtatgt atctagagaa gatagcagag agcttgaaga aggcgaattt tttatagcag
    68341 atatgattgg aatggaagtt ttaactgtag atggaaaata tgtaggaata ctagaagatg
    68401 ttcttcaata ctcagcaaat gatgtctatg tagtaaaagg tgaggaagat aaagaattta
    68461 tgataccagc tataaaaaaa tttgtaccta caatagatat tgatgaaaga aaaatgatta
    68521 tagaccctat taagggaatg atagattagg tggtaatatg agatttcata taatgacact
    68581 ttttccagaa atatttaatt cgtacatgga tgaaagtata atgaagagag cagttgaaaa
    68641 aggtataatt gaggttcata tatataatat aagggatttt tctaataata aacataaaaa
    68701 agtagatgat tatccatttg gaggaggagc ggggatggta atgactcctc aacctatata
    68761 tgacacatat aagcatataa taacaactca taatataaat aacccaagtg taatttatct
    68821 tactccaaaa ggtaaggtat acaatcaatc tatggcaaag cagatgtctt taaaagaaga
    68881 tataatacta ctatgtggtc attatgaagg aatagatgag agaatcattg atttaatagt
    68941 tactgatgaa atttcaattg gagattatgt attaactggg ggagagctcc cagcacttat
    69001 aatgatagat tctatatcga gattaatacc aggtgtatta aaccaagaag aatcatttga
    69061 agaagaatca tttaaagaca acttattgga atatcctcat tacactagac ctagagattt
    69121 tgaaggatta aaagtaccag aagtgctttt atcagggaat cataagaaga tagatgagtg
    69181 gagaagagaa gaatctataa ggataaccaa agaaagacga tttgatttat ataaaaagtc
    69241 taatgaaaaa taaaaatata atgaaaaatt aatatatatg tatacaataa agtacctata
    69301 aatggaatta aaaacataaa agtgcttgta ataactattg aagtatagta taatataaaa
    69361 tgttgaaaat acgggcgttc ctctgtttac actggtcggg tagttaagaa cgtctatgat
    69421 atctaggagg aagaaagatg aatgaaatgc taagagcaat tgagcaagaa caattaaaaa
    69481 atgaagttcc taattttgga cctggggaca cagttaaagt acacgttaga attatagaag
    69541 gaaaaagaga aagaatacaa gtattcgaag gtgtagtatt aaagagacaa ggtggaggag
    69601 caagagaaac tttcacagtt agaaaaatgt ctttcaatgt tggtgtagaa agaactttcc
    69661 cagttcactc tccaaaaata gaaaaaatag aagttactag aaaaggtaaa gtaagaagag
    69721 ctaaactaaa ctacttaaga ggtagagtag gtaaagctgc taagataaaa gaagctagaa
    69781 ataaataatt aaaaacttta cttataaatg gggggctgat ttatcagtcc tctttctatt
    69841 ttaatgaaaa ttacaacaaa taattatact agaaataaat agaaatattt gttgaaaata
    69901 tagattattt atctatgaat ttatagcttt taaaatgaaa aataaaattg gtaaatattg
    69961 cattatattt tgtaacgata ttaaaaataa gagaacagta ttatgtaaag tatgacgtta
    70021 aaaagatgac aatattatag tttgtgaaga tatatttttt aagtggaatt aggatataat
    70081 aatataatat taataaggag tgatacatgt gtcaaatgaa tacgaagagt atcttatgga
    70141 tgacaatcta catataaact ggtatccagg tcatatgaaa aaaactaagg agttagtaaa
    70201 aaataactta aaattgattg atgtagtaat tgaacttttg gatgctagaa tcccgtttag
    70261 tagtaaaaat ccagacatag acaggcttgt aggagataag ccaagagttg tcgtacttaa
    70321 taagagtgat atggcagata gggataaatt gaatcaatgg attgaatact ataagaaaat
    70381 taatatcaaa gctataccag tagatacaat aaaaggtgtt ggtataaata agataatcga
    70441 agaatgtaaa aatgtaacta gagaaaaaat gagttcttta aaagacaaag ggagaaaaga
    70501 aagagctata cgaataatga tagttggcgt tccaaatgtt ggtaaatcgt ctcttataaa
    70561 caaattaaca ggtagaaaaa gcactcaaac tggagataag ccaggagtaa cgaaagggaa
    70621 acaatgggtt agattaaagg gaaatcttga acttttagat acgcctggaa tactttggcc
    70681 taagtttgaa gaccaagaag ttgcattaaa tttagcattt agtagagcta taaaggatga
    70741 gattttagat actgaaactt tggctttaag acttatagaa aaacttatga aaatagaacc
    70801 tgagaagttg aaagccagat ataagttaga ttgtctagga gaaactccaa ttgaaactat
    70861 ggatatgatt ggtcataaaa gaggatttat aacaggtaaa aaagaactag attatacacg
    70921 catagccaca actgtattaa atgaatttag agatggaaaa ataggaaata taacattgga
    70981 agttccagaa aacgttaaaa gatagatttt aaaacaaaat caaaaattta atgttaaaaa
    71041 tttaaaaaag ccttttagca aaggcttttt tatttttttg aaatatagac aaatatctcc
    71101 atataaaagt ataaattagg ttagaaagcc tttaaaaata ttaatttaag acaaatatac
    71161 ctaatatttt gaaaattaaa atgagtgtga ttattaaaaa ttttagcata ttgacttgct
    71221 tgtttcgtat aatatataat aagcacaaat aaatacaata tattaaaaat ttaatttatt
    71281 taattttatt aatttaataa taagttctta ttgtttaatt caacttactt atgcaagcgt
    71341 aaacaatcga gacattttat taatttaata aggttaaaaa gggggatttt ataatgggta
    71401 agaccaagga tgttatagta tttggatttg cgttatttgc aatgttcttt ggagcaggta
    71461 acttaatatt tccaccttac ttgggaataa ttacaggtcc agaatggtta attgccttct
    71521 taggatttac gtttgctgat gctggattgg cacttctagc agtaatggct acagctaaat
    71581 tcgatggaaa cgtagttgaa atgtttaaaa gatgtggtat gaagttaggg attcttatag
    71641 gttgtgcaga tattttatgt ataggaccat tcttagctat accaagaaca ggtgcaacaa
    71701 cttatgaaat gggtataatg cctttatttg gaacttcaat tccagtgtta ttattctgta
    71761 tacttttttt tgcgctttca tatgtactaa caataagacc ttctaaggtc gtagatatag
    71821 ttggacagtt tttaactcca gctcttttaa tagctttagc atttataatt ataaaaggta
    71881 ttatatcacc tcttggagat atagtagata aacctatgat acctaatgta tttgcagaag
    71941 gtataggtca aggatatcag acaatggatg cttttgcagc aatagcactt gcatcagttc
    72001 taatagtatc tttaaatgat aaaggatatt ctactattag tgacaagtta aaaatgattg
    72061 gtaaggcggg tgttcttgct tgtggaggat tagctctagt ttatggagga ttatgtttcc
    72121 ttggagcaac tgtatcaaca atgtatggaa cagatgcagt acaatcacaa gtaatagtaa
    72181 atataactga aggattgctt ggaaatgttg ggaaagcgat tttagcagta gtagtatcat
    72241 tagcatgttt aactacatct ataggtctta catctgccac aggtcaatat ttctctagac
    72301 ttacaaaagg taagttgagt tatgaaaaaa tagtattagc tgtatctgta ttcagtgcag
    72361 tagtagcatc ttttggtgtt ggaactataa taaagatagc atctcctata ttaagtatag
    72421 tttatccacc atcaattgtt ttaataattt tagctttctt caatgaaaaa attaagaatg
    72481 ataatgtgta caaaggagca gtatatatgt cattgcttgt aagtatacta acagttatat
    72541 ctagttatgg agtagctgtt ccagtagtaa actctttacc tcttaattca ttaggattta
    72601 actgggtggt gcctgttata atagctggaa taattggcaa ttttatacca tcaaagagtc
    72661 aatctaatac acttggaaca aactaagttt tatttaatta aaatataatc aattgtaaat
    72721 aaatgagtta actaaaagta aaaggagtta tttgtacaaa taactccttt tatttttaga
    72781 ttctatactt aattatttgt atttaat
//
LOCUS       DAJMZY010000005        71912 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.005, whole genome shotgun sequence.
ACCESSION   DAJMZY010000005 DAJMZY010000000
VERSION     DAJMZY010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 71912)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 71912)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..71912
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.005"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            <1..364
                     /locus_tag="OE968_000312"
     CDS             <1..364
                     /locus_tag="OE968_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCP7217629.1"
                     /translation="LDELGARVSAHLRREKRKSNQTKIKFYNDLTIDYEKRLICIDNN
                     QISLSKKEFDIVELLSMNPGQVFDKEKIYDRVWGYNSNGNSDVIMEHIRKIRIKLSKH
                     TLENYIETVWGVGYKWIK"
     gene            352..1512
                     /locus_tag="OE968_000313"
     CDS             352..1512
                     /locus_tag="OE968_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HCP7217630.1"
                     /translation="MDKINNMSLKKAFFVLTLSSLIIASTLTTFSYILLNNLYNSIQD
                     KYLKTPINTGFITIVQNNVNQFSDYDKTLLNIINILQLVLPLIFFIGLLLLADIIFYK
                     VKLKTPIEILNKGAMEISNNNLDFCLEYNNNDELGNLCNAFEKMRSELNKNNIKMWTM
                     INDRKQLNAAFSHDLRNPLTVLKGYSNYLTKYIPTGKLSDEKILSTTQLMSEHINRIE
                     YYVENMSNAQRLEDLVVSKSMSNINKFIENLDENISIIAKQEGKSFTLKSQINNINLF
                     FDENIILRVVENIISNAFRYARNNVSILIYLEQELLTFVIEDDGIGFSKESLKLALRP
                     FYRDKTLNDSNAHFGMGLYISKILCEKHGGSISIENNSTNSAKITAKFSTRN"
     gene            1783..2256
                     /locus_tag="OE968_000314"
     CDS             1783..2256
                     /locus_tag="OE968_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HCP7217631.1"
                     /translation="MLSFTFCSLPFWICYFWCGISDIFDGLIARKLRQQSGIGAKLDS
                     IADFIFSVTILVTVGKNIALPMYLWWCIVAIALLRLISYSIGFFKYRTFSSLHTLMNK
                     ITGISIFAFPLLYICFGLDVAGIMICIVAFLSSFEEIAIMIKSKELNRDIKSIFM"
     gene            2542..3210
                     /locus_tag="OE968_000315"
     CDS             2542..3210
                     /locus_tag="OE968_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCP7217632.1"
                     /translation="MIIKAKQLSKIYGSNNNKVIALNNVNLEINSGEFVSVIGPSGSG
                     KSTLLHILSGLDNPTSGQVLLDDKDIYKHTEKELSALRRKSFGFVFQQFNLLPVLTAS
                     ENISMPVLLDKKQPDKEYLNEISSLLGIADRLNHLPHELSGGQQQRVAIARALIAKPD
                     IIFADEPTGNLDSKSGSEVMNLLIKTSKQFGKTLVVITHDDRIAKLADRKISIIDGVL
                     MEVK"
     gene            3213..5681
                     /locus_tag="OE968_000316"
     CDS             3213..5681
                     /locus_tag="OE968_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCP7217633.1"
                     /translation="MKNYLSLSIKELKSQKLMTTFIIIAIVLSTIMTTVVGQSIGILQ
                     NLRIEQARSFNGDRHVSFHQLTKNQVDDIKKDDRVYQAGTSITLGSSKIKDSGISVLV
                     KEYDKTGLSNYPKLMKLKSGNLPKDKNEIALDENTLKLMGIKPRLGVTIPMNLDISLL
                     NDTIPPYNYTANFKLSGILEDDYTGYVSGIVNGIVGKGASENLLPKRYILSSLDFKIK
                     QQEKFQEIVNQLAKKINLSHNSIQYNWIYLNALKIQFEKDENSSNSDGISMIILVSLF
                     VALLVLLASGLVIYNILKISVTKKIKEYGCLRAIGAEPNQIYKIVILQILILCTIAIP
                     IGAVIGIISSKGITGMVTNILNPDILLANDNKEITELIHKNTTAYIFPLVLSTSISLI
                     FSLISALPSAIYASHVSPKIAMAGSTTKIKRKIKREKTIKNFERHLAWLNLKRNKGRT
                     IITILSLFMSITVFVALSEFSNVLDVSRSVSNLKEGDFSLTNEISGFDKSILDKIDKM
                     KNVNRTSFIKYSEYKQGEIDTDINFENSGEMLKIIGIDEQTLKDLMPSITDSILEDFK
                     NGSICFIKNPIAISTPGVKTRHTNLKPKDNITINKKQLDIYSTVDKMFFLQGNGWING
                     VDVIVYDSVYNTLTNKNKFNQINIYAKDKSKLEQIRLSIEQICENNPGSHWISYIESD
                     KQLKESFKQIEFLAWAVILFVGLIGTLNIINTTHTNINTRTNEIGVKRAIGMSNSSLY
                     KMFLWEGVYYGIFATIFGSIAGYVSAIIINMATIEKLDFTNIPITSILQATIISILAC
                     IIATLIPLRKVKKMNIIDCIDVNL"
     gene            complement(5920..7344)
                     /locus_tag="OE968_000317"
     CDS             complement(5920..7344)
                     /locus_tag="OE968_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HCP7217634.1"
                     /translation="MKNQSLITQFRHTFIFIIIASIVATVITYVFALYLYIHSLNKDI
                     YPPNYYERQVPRIEKYINEKNITLLSQSNEEGLKRTIRGDDMLYQVVDNNGNILYGTN
                     PKKLFKTKEELFNNFINKTVRKGGYIHTVPIKGDNGKIEGAVILFYQVKITFANIRGR
                     FVFAVIIMALFSPFLYIVGFTRWLSKRFVKNINQPLHLLIDASKKIKEKDLDFEIDYY
                     SDNELGKLCSAFSEMKDELKGSLSAQWKMEQERVEMVEALAHDLKSPLSIILGYTDAL
                     IGNNTDDNEKLHRYLTVIRENTEKSAALVQKMQYTSDLEKSNIQLNLVPINLPEFLRQ
                     KVQDYELQAHQKEVELILKMQGNIQSPIQIDVDRLTRIFDNIISNSLQYTPSGGNISI
                     TVKDEKNCISYEICDSGRGFSSKDLKKALDKFYRGDEARQTKGGHSGLGLYIVKQLVE
                     QLGGSVKIENSKSGGACVKFWHSI"
     gene            complement(7363..8055)
                     /locus_tag="OE968_000318"
     CDS             complement(7363..8055)
                     /locus_tag="OE968_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCP7217635.1"
                     /translation="MSKILIIDDEMDLVMLLEDELKAKGHEVLIAYDGQAGIELSKQE
                     PDLIILDIMMPKMNGFEVCQAIRDDVLCPIIFLSAKQSETDKIKGLTFGGDDYVTKPF
                     GLRELMARIEANLRREKRSQYINEENKRSTLYFGKLCLYMKERAIKIDGKNIDLTKIE
                     YDIVELLALHAGQVFSREQIYEKVWGCDSEGDSSTVVERVKKIRAKFSAVTPEKEYIS
                     TVWGIGYKWNKM"
     gene            complement(8110..8886)
                     /locus_tag="OE968_000319"
     CDS             complement(8110..8886)
                     /locus_tag="OE968_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutG family
                     permease subunit"
                     /protein_id="HCP7217636.1"
                     /translation="MIKLLSSEWLRAKRTAVQWLTLFMPIIFSLCVVFYLTTKSGSTQ
                     EFAFEGFFTVWTVFIIPIGVGILAGFIVQEEELAGNFNGFLCVGISRVRLYLGKFLFL
                     LFCLTICTFIATLILCIGMSIAVPSGATIWLFLSAAGLVVIGTLPLLAIHLWVSFAWG
                     MGASIGISIGGILMAAILGLTSVGEKVWAFVPWTWPVKLGMLPGIYFIKEAGTISTEA
                     FYSKVMQTASIELIVVAIGLIIFLIGGVIWFKMWEGRKSY"
     gene            complement(8883..9653)
                     /locus_tag="OE968_000320"
     CDS             complement(8883..9653)
                     /locus_tag="OE968_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutE/EpiE
                     family permease subunit"
                     /protein_id="HCP7217637.1"
                     /translation="MNALQSELLKYKRTFMGKLIVFFPVSFAAYAFIMQSTLMQNPLS
                     QTTSWAWQSLLALIFNWWSFLFLPIGFALFATLVAFQEKKAGNYRALRTHNVSPMTLW
                     INKVIAMAVYSFISTLVLIVVTIITGLILKAGPVPFGQIIGASIVCWVVSLAILPLQL
                     WLATWKGMFLSMGVGALGMIFGVLAATKPFWIAVPWSWAVRMVCPIINIHPNGTILEA
                     GDPLLNTSVIPIGIVVSLVVFIVLTALTAAWFNRRDDK"
     gene            complement(9650..10354)
                     /locus_tag="OE968_000321"
     CDS             complement(9650..10354)
                     /locus_tag="OE968_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014466355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic protection ABC transporter
                     ATP-binding protein"
                     /protein_id="HCP7217638.1"
                     /translation="MKDLILETKNLSKRYGEQMAVNNVSLQIERNSIYGLLGPNGAGK
                     STTLKMLVGLLRPTNGRIIFDRKPWKRESLAKIGSLIESPALYGNLTAEENLLVHTKI
                     LGIPKDKIYEVLEIVNLKNTGKKRASQFSMGMKQRLGIAIALLSDPELLILDEPTNGL
                     DPFGIQELRELIASFPKKGITVILSSHILSEVAQVVDNIGIINGGRLLFQGMPDPNEN
                     LEEFFTDVILKGGQNR"
     gene            complement(10609..11121)
                     /locus_tag="OE968_000322"
     CDS             complement(10609..11121)
                     /locus_tag="OE968_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7217639.1"
                     /translation="MKKISQEKISTHIQEVPQEKIEQWKSLYEKYKSILKVNSKSVLE
                     IIEFLKRKYVIVEETSEEFKHVVINNIKLNKPFSQKISSDKELKPIVFTIPNEGNAKK
                     LYDTQEEIYSGCKIIVGMEFETGYVFVEGSDELNDEITSFKGLDKYDINNYYLVANYI
                     RCLKKYKLID"
     gene            11447..11704
                     /locus_tag="OE968_000323"
     CDS             11447..11704
                     /locus_tag="OE968_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7217640.1"
                     /translation="MILNRAELFRGYSLNRFNEICNILSVNKIKYKYKVKNNAYSKKP
                     FFNEITLGNLGQKEDFSYEYLIYVHKDDYEQAESLINSKLR"
     gene            11847..12473
                     /locus_tag="OE968_000324"
     CDS             11847..12473
                     /locus_tag="OE968_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HCP7217641.1"
                     /translation="MKINIKSKLSEFIKQNNLFDDSRIISYLPNITIETDKIKTIMIN
                     EVVPTNTNDDFYSVDKDADYLKTTIPLFDSAGIKVSNINDILDMGIYITNAVKLPKSE
                     YTITRDTIKLHMPILEEEIKLFKNLEVVMLMGDVAKKSFNMITKKHIKKNVIPSISTY
                     KLRNNELYYDNLRVFPSYIMTGGNILIEKSKFEMASEDIKKMFEIING"
     gene            complement(12720..13499)
                     /locus_tag="OE968_000325"
     CDS             complement(12720..13499)
                     /locus_tag="OE968_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901940.1"
                     /note="N-terminal region resembles flavodoxins. C-terminal
                     ferrodoxin region binds two 4Fe-4S clusters; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EFR1 family ferrodoxin"
                     /protein_id="HCP7217642.1"
                     /translation="MNSKIYYFSGTGNSLVVSNILKETLNGSKEVIPLAIHRKENNID
                     INEDILVIVFPVYFADVPDIVKSFVEKLNFNINTHIYAIATCNGVAGHSLFTIDKLLK
                     KRGKKLSAGFLINMPGNALITPPDVEEERLKNQTNRVAEIAKCINNLEIGNIEGKNNL
                     KSHIDSVVLRLVGKNMQIATTKFFAENKCNRCGTCKRVCPVENISIVDKKPKWGNECE
                     RCLACFHWCPKEAINVKKSFLTNRKKYHHPDITVKDIFLDK"
     gene            complement(13567..14028)
                     /locus_tag="OE968_000326"
     CDS             complement(13567..14028)
                     /locus_tag="OE968_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HCP7217643.1"
                     /translation="MGGARDYLNGGKMKDFEKLYEATTKLVSTSLKVKDDLKKMFKQN
                     GYDITTDHYALLRFLWEQDGISQIDLCEKSCKDKSNTTRILDVMKNKGLIVRKVDVKD
                     RRKFQIFLTDLGRELEEPLNEIASIYATETFKSISDEELPLFTDILDRIGK"
     gene            complement(14004..14681)
                     /locus_tag="OE968_000327"
     CDS             complement(14004..14681)
                     /locus_tag="OE968_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HCP7217644.1"
                     /translation="MIITVINGSPRKNGATSKVLTYLYKDIERLIPDVKINYFDLSEV
                     NPSYCIGCLNCYKMGKCINQNDKVEYIHDIITKSDGVIFGSPTYGSSVTGLFKVFTDR
                     AHMMLERLLYRKPCIAVTTYENARGSKAISFIKSMVLDSGGYVCGSLSIKTGFNQNPI
                     TEKVESKIQKVSKKFIYCIEEKKNPPVLSQIYNFIAINAVLKPMAFKDIEQYKGIIDR
                     WEEQGII"
     gene            14914..15300
                     /locus_tag="OE968_000328"
     CDS             14914..15300
                     /locus_tag="OE968_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HCP7217645.1"
                     /translation="MKKLPHISEAEYQVMKIIWKYAPISTTEVIEKLVETSTWSPKTI
                     QTMLLRLVKKGALTYEKNSRVFVYTPLVKEEEYVATESSSFLNRFYNGTLNSMVLNFL
                     ENDKLSEDDIEELREILNKRTTKGDK"
     gene            15303..17102
                     /locus_tag="OE968_000329"
     CDS             15303..17102
                     /locus_tag="OE968_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaR1 family beta-lactam sensor/signal
                     transducer"
                     /protein_id="HCP7217646.1"
                     /translation="MYAPFFIRFLLSTLTLSILIVVILLAKKVFKKHISAKYQYNIGF
                     ILLIMLIIPFVPLKYINLGNVFNYLYTFNQLGSSTNRTSMIKNSSNSVINNSNALNDF
                     SVSLNQVNFDSLNILLLISWIIGILIMIAITIHCNIKIKNMKKSIQILKDEEIVFIFE
                     KCKKDIGINKDFILCKSPIINTPITFGYFKPHIILPDKSISKLSLKDIKYILLHELQH
                     FKNKDILINYIMCFLQILYWFNPLVWYAFKEMRIDREIACDISVLKKLNKDSHIEYGQ
                     TLINFVDNISRPSNLTLTSDIGGSKKQIKKRLLKIMDFHNESNTLKFKSILIFTLIAL
                     IVFGNIPKLSIMADINEKYRPTNEQTVYEDLSQYFKGFDGSFVMYDLKSKQYHIYNKE
                     KSKTRISPNSTYKIYSALLGLENGIITRNNSHIPWDGKHHSNSSWNEDQDLFSAMENS
                     VNWYFQTLDKKTGLKNIQTYLRQIGYGNYDVSGGISNFWLESSLKISPIEQVELLESF
                     YTNKFKFEDKNIETVKDSLLISKKDGVSLFGKTGTANINGKDVNGWFIGYVEKNENTY
                     FFATNIQSKDYSNGSSASKITLSILNDKKIYNP"
     gene            complement(17457..19331)
                     /locus_tag="OE968_000330"
     CDS             complement(17457..19331)
                     /locus_tag="OE968_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HCP7217647.1"
                     /translation="MNKYNKIANELIKIIGEDNIISITHCATRLRVMVKDREIINDKK
                     VEKVDEVKGVFFTSGQYQIILGTGIVNKVYAEVEKMGLKTLSKKEQDELVKNNETGFK
                     KVMRTLADIFVPIIPVIAATGLFLGLKGCLFNDNVLGLFGMSSANIPLYIQTLVSVLT
                     ETAFAFLPAIIVWSAFKVFGGTPVIGLVIGLMLVSPILPNAYSVADPSNEIEAIMAFG
                     FIPIVGCQGSVLTAIVTAFIGANLEKWFRKHMPNVLDLIFTPFFVMLITMLVILLGVG
                     PIMHTIELKMVDIISLLIDLPLGIGGFIIGFTYPLAVITGLHHTYVMIETSLLANTGF
                     NALITLCAMYGFANIGTCLAFMKKSKNNQVKQTAVGAMLSQLFGISEPVLFGIQLRYN
                     LKPLIIMCASSGLGAAILSILHIQSNSYGLAVLPSYLMYIYDGYNLITYLLVSIFVVA
                     FCFIVTCLFGVPKEAINEDEDEELVFNENNENFVSPAKGKIVALENVPDETFSKKMLG
                     DGFAIDIIDGKIVSPISGKLETVVSSGHAFGIKGTNGEVLIHVGIDTVALNGDGFDVA
                     VKQGDMVKQGDVLVNVDLKRIHELGKSTLTMVLFPDGKKVNILDINKDVKIGQRICVE
                     "
     gene            complement(19336..21000)
                     /locus_tag="OE968_000331"
     CDS             complement(19336..21000)
                     /locus_tag="OE968_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HCP7217648.1"
                     /translation="MEKKWWQKEIVYQIYPRSFQDSNNDGIGDLQGIISRLDYLKNLG
                     ITSLWLCPIFKSPMDDNGYDISDYLDIASEFGSMEDLKELIKESKDRGIKIILDLVLN
                     HTSDEHPWFQEALKNPESPYHDYYIFKKGNDLPNNWRSVFGGSVWEKVENRDEYYFHS
                     FGKKQPDLNWENPILRSELYQMINTWSQMGVAGFRVDAITFIKKNLSFQSLESDGVDG
                     LVKCTKTVRNQPGIEKMLYELKENTFKKYDCMTVAEAAGISYDQLGDFIGEDGFFSMV
                     FDFKHADLDVASGSEWFKRISWTIPDLRKCILDSQMYVQEHGWAANFIENHDQPRATT
                     KYLLQYERNDDAVKMLGAMYFFLRGTPFIYQGQELGMTNFKRDTINDFNDLSSIDQYY
                     RSIDESYSEEEALEFVNLRSRDNARTPFPWADKENAGFSDTTPWLKVIENYKDINAQS
                     QINNSESILEFYKKMIKLRQDSEYSDCLIYGSIEPIDIESDDIIAYRRQLDLVVIDCY
                     YNFSDKPVEIRVEEKYDIVFQNLDDINLLNKTVRLKPFHAVLLKVR"
     gene            complement(21014..21835)
                     /locus_tag="OE968_000332"
     CDS             complement(21014..21835)
                     /locus_tag="OE968_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HCP7217649.1"
                     /translation="MKLYKLLILDIDGTLRDEVYGIPESAKHAIRLCQKNHCSVVICT
                     GRSMGTIQDDVLSLGVDGYIAGGGNYIQYHGELLYNQSFNQRLIKEVVCLLKKREVAF
                     SIESQEKVFMNQKAKEIFETMNQLKGTNSCINKQHIQEKITYENNIEEYKSQDIHKIC
                     LWSNEKVFDEVKNILQDKMELAQRDISSQYYEIIQKDFHKGKAIKRLQERLGVTQKET
                     ICFGDGQNDVVMFQASDVTIAMKNSHQQLKDIATSICEDIFDNGIYKELKRRNII"
     gene            complement(21934..22698)
                     /locus_tag="OE968_000333"
     CDS             complement(21934..22698)
                     /locus_tag="OE968_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HCP7217650.1"
                     /translation="MKIEGLFNKYYNSFTANDKYICECILNHKEDCIKLSIDEFADKY
                     HISTSALSRFAQKLQLPGYSELRVIIRLNETEVEYKNQSKHQLMDCYNKVIDDIEKKD
                     CSIMFERMKKANRIIVFGEGYSQERVAKEMKRIFLPTGKIIYDVYGYDMIQALNHFIK
                     TDDMIFFISLNGDASTIIDFAKEMRMKGIYMVSITKMISNPLARLCDENLYIQSISIS
                     VDKQLDYDVTTPYFILIELLYIKYKMYLESEHIPRK"
     gene            complement(22695..23444)
                     /locus_tag="OE968_000334"
     CDS             complement(22695..23444)
                     /locus_tag="OE968_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HCP7217651.1"
                     /translation="MRLESLVNQNYDNLNENDKIIIKQILICQREYRNFSCEKIANEC
                     NVSRATLLRLCRKIGLDSFSDLKYLLKNNQLEFVNNDNNFHDVCENYRLLMNELQKIS
                     FQDICKIIYDAETIYIYGTGNEQKSLAQEIKRIFLSVGKCVIDLFDIGEIEFMRESFQ
                     KNDLFIIISLSGETKAGIEIAKFINNHIHTISLTRLDNNTIATLCEYNLYVETQKLDT
                     LQAISYEVVGAFYALLDLLHMNYIEYRRRKE"
     gene            complement(23948..24553)
                     /locus_tag="OE968_000335"
     CDS             complement(23948..24553)
                     /locus_tag="OE968_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HCP7217652.1"
                     /translation="MKIKENVLMLDSTRGSNCFIVFDKEIILIDTGLPFMGKNIIKEL
                     KTLGIKLTDIKHILLTHHDVDHISNIKLLKEKTGAKVWAHVEDIPFIIGEKDRPGFKK
                     FIGKAISRRLIKDVEPYGENMQIGNIKIIHTPGHTPGHVCMIFEAVLFAGDLVKNKNG
                     NIVPYPNPWNWDYKKMVKSIRELDNLKYEWICMSHGTPCIK"
     gene            24732..25370
                     /locus_tag="OE968_000336"
     CDS             24732..25370
                     /locus_tag="OE968_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCP7217653.1"
                     /translation="MSELSKRDKEKIQRENEIIDKAEKLFCLNGFDNTTMNELAKEVE
                     YTKRTIYKYFSCKEDLFFAVVLRGYKRLWDNVKIESAKGKTGFEKIKLSYFAFHKFYS
                     VEPSLLCLMGMIGIVNSEKSDTDMLFKEKFFSFNKFMFDEIQGMFEIGKNDRSIRHDI
                     EIPTLMYSSIFTLTGFFNLLSVTGKSYLNNFNIDEEKFIETTLALLIDSIKA"
     gene            25502..26164
                     /locus_tag="OE968_000337"
     CDS             25502..26164
                     /locus_tag="OE968_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCP7217654.1"
                     /translation="MAKILLLEDDDTITFGIKTSLEKKNHTVCCYNTIAEAKKNFDKT
                     IDLILLDLNLPDGIGYEFCQYVKSIEDTPVIFLTVRDDEKDIIRGLDMGADDYVVKPF
                     LLSVLQSRINAVLRRTHSNTNNTITCENISLNKVEVKAYLDNVEVPLTAGEYKLLLSL
                     MENKNRAMTRTKLLEMLWDVDGNFVNDNTLTVTIKRLREKLKNPPCIKTLRGIGYRME
                     DS"
     gene            26164..27345
                     /locus_tag="OE968_000338"
     CDS             26164..27345
                     /locus_tag="OE968_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HCP7217655.1"
                     /translation="MKTPRNINSTVVFIIFCLIVTFLLSVILTTITSFNEYNVLSKAL
                     GASYEYNPKSTESILKSLKNSSDKDFKTGNEILSKHGYSKSTFWSKNFFYFLVISFGI
                     ISTMATVIYIIKHRTNKQKLSRINNLTQYLEEVNLGKESVLLRCEDEFSHLEDEIYKT
                     VGELRCSKEFALKERQTLSDNLADIAHQLKTPITSMSLMAQLLSENCPDEEIDYINRL
                     TNQISRLERLVSSLLTLSKLDASTLIFESKLIDVHSLLTYAIEPIEGSLREKHQTFTI
                     EASPSVEFEIDINWTLEALLNILKNCSEHIEDGGYIVAYYSQNPLYVEIIIEDNGKGF
                     AQEELPYIFNRFYRGKNASKDSIGIGLALSKSIIERQNGTLHAENCHNGGARFIIKFY
                     T"
     gene            complement(27526..30186)
                     /locus_tag="OE968_000339"
     CDS             complement(27526..30186)
                     /locus_tag="OE968_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCP7217656.1"
                     /translation="MNILQEYTLDFVRRNKRSSIAIMLAILLTTTMMSSLCGLLYTMW
                     TDFIRLSIEKEGNWHGELFDYTYGSDLPLIENFSSVDDVMVKGQWYVGKINDEKRDYI
                     IYRNATSEYWNSMPEKDTIIEGRRPNNANEIALSKQYFENNPSVKIGDKITLPIGYRI
                     LNGKPLEPIAPKSKGESFKKISEATLTIVGKVDVSTSSVIPAYTALGYLDKTSIKPND
                     SITVYLRFKNIRDTYKELPKLAKSLGWKTNEYGKYNLKYNSNYLLKMLVFSPEQKASM
                     SSISKFSTPIMYLTIAIFTVAVFVMVIYNAFSLSANARLTQLGILSSVGASPKQIKRS
                     VVFEGFLLTIIPLPIGLFLGWLLCNRLIVYVNSVNYHTDVPEVVFTYGIPAFLPAVLL
                     TIVTVWISALIPARKVSKISPIEAIRQGDSVKIKKSHKYSLGKIFGIEGELASNALRA
                     RKKSYRTATISLTLSFLLLTCFLHIIANQEGAKAVYGSDNYKDQRDIAVYLENSEPIE
                     SAFIEKLDNTEGVKSSLYYQKMSASTWLTEKDASKELAKNGGFKSIVSSKKYSPIERD
                     GKFRIISNIIGLDDKSFTEYCRQISVDPKLFYNTKNPTSIVYNKEEDINRSTRRNKVY
                     IDYLNLSIGDNIKLNEKVYDEDKGDYTYNMKVGAITSTLPKIVDTSSKYTLMQIVPMS
                     MVQEISKNYDEVSRLRSNRLIGVFKVNNREDIPRVREKLESIYNKDYGSGDYSIEDVL
                     ESEKQKASGIKTMNLIVGFITGLLAMIGLSNVLATVSGNIRSRRQEFAMLRSVGLSPE
                     GIKKMLILEGLFLGITPLLLSIPVQIGIVYAFLRINEIYFIEYLPFAPISTIIGFTIL
                     ILFIVIASYMTGYKQLKNENIVESIKNETI"
     gene            complement(30183..30866)
                     /locus_tag="OE968_000340"
     CDS             complement(30183..30866)
                     /locus_tag="OE968_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCP7217657.1"
                     /translation="MEILKCENLTKIYGSNQTRVTALNNVNLSVQKGDFVSIVGASGS
                     GKSTLLHLLGGVDRPTSGKIYVEDTEISSLKEEALAVFRRRKVGLIYQFYNLIPTLDV
                     RKNILLPMLLDKRKVDEDRFSEIVSILGLSDRLNHLPSQLSGGQQQRVSIARSLIYRP
                     AILLADEPTGNLDRKNSEEIVDLLNLSNKRFNQTILLITHDEKIALEANRIVTMEDGV
                     IVSEKVVKK"
     gene            complement(31210..32163)
                     /gene="blaCDD"
                     /locus_tag="OE968_000341"
     CDS             complement(31210..32163)
                     /gene="blaCDD"
                     /locus_tag="OE968_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDD family class D beta-lactamase"
                     /protein_id="HCP7217658.1"
                     /translation="MKRKKNFIWIAILLVGVVMVMYYVGKKHNDINQKTDKNYIKSEL
                     NKSELNKSKIENNDKNKKEKINMVDYSDCFEGISGGAIFYNTKNKEYNIYNKELIETR
                     RSPCSTFKIVSTLIGLEKGVINSKESVMGYDGTEYPNKNWNKNLSLEEAFKESCVWYY
                     KKLIDKVDAKSVQNILDDLKYGNCDISEWEGDLKNGKGHLNGFWLESSLQISPKEQVQ
                     TMAKIFEGDTNFKKEHINILRDIMKIDINDKNINVYGKTGTGFDEKNKRVDAWFVGML
                     EREGDTYYFAIKSDDSNKEITGPKVKEIAINIIKKYYSVRE"
     gene            complement(32704..34818)
                     /locus_tag="OE968_000342"
     CDS             complement(32704..34818)
                     /locus_tag="OE968_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding domain-containing protein"
                     /protein_id="HCP7217659.1"
                     /translation="MSENKQVVNCDIIASNSKHNMCEYDAELLTFFPDEIAHLIEINN
                     KLDNAFKKAENLVDKLDKDYMDAKMYMVKNRGEIDPHEMFQNEQGLKQIDNYGAFMVK
                     VRDKINKIKDSPYFARIDFRLKDMDDESKYYIGRFAFDYEDELIILDWRSPIASMFYD
                     YEIGKAGYDAPIGWVDGEITRKRQFKIKNGKLEYALESSINIQDDILQKELSHTSDEK
                     MKSIISTIQKEQNQIIRNDKADTLIIQGVAGSGKTSIALHRIAFLLYRFKDKISANNV
                     IILSPNKVFGDYISNVLPELGEEPLCELSFENIAEVQLDRVINFESEKDPLEINDAKW
                     SERVRFKSTLDFVKLIDDYIKQMPNKIFIPKDYTFGSFTAKSDWIQSRFEAYNRYPVK
                     KRLEKVAEDIHYKFESDNIMEEDLPKVKSILKSLNGMLTIKNTLTLYKDFFKQMNISN
                     MFVMAEKKTLEWSDVYPFIYIHAAYEGIQEDKIIRHIVIDEMQDYTPIQYAVINLLFK
                     CKKTILGDFGQLVNPNHTHTLDDMKQLYNDGELVMLNKSYRSTFEIINFAKKIQDISS
                     LEPIERHGEEPALLKCNNEQDEINKIKIEIEEFKKSDNATLGIILKTDNDAKAVYDAL
                     REEYSVHLISSESSSFTKGVSITSIKMSKGLEFDEVIVPSVNNKTYYSDYDRSLLYIA
                     CTRAMHKLKLTYTCELTQLIDM"
     gene            complement(34902..35738)
                     /locus_tag="OE968_000343"
     CDS             complement(34902..35738)
                     /locus_tag="OE968_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCP7217660.1"
                     /translation="MSYKVINVITAIDYIEEHLSEKLDLDIVANAVHYSKYHLHRTFT
                     TSVGLTMHDYIKRRKLTEAAKLLVFSKKPIIEIALIAGYESQQAFTSIFKAMYKKSPN
                     KYRKEQEFYPLQLRFVLKKDNLFSKNVLELEKEIKLASMSDIPLWMNLVRLVIDGFPN
                     LQEEEYIYQLEQYILEERALILKLNNVAIANMVFNRETRSIDFFGIHPQYRNSDIAQV
                     FLKKVIEDFLIDTDISITTFREGDKADTGHRDMIKKLGFAEAELLVEFGYPTQKFILP
                     LS"
     gene            complement(36322..36684)
                     /locus_tag="OE968_000344"
     CDS             complement(36322..36684)
                     /locus_tag="OE968_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HCP7217661.1"
                     /translation="MKIYDILTRFYIQDIEKAIPFYENLLKEKCSLRFSYKEVGLELA
                     QIGNVLLLSGSDDALKPFIETKSTFMVDSVDEWRSYLLDNGAVVVRDKKKVPTGYNMT
                     LRHPDGTIIEYVQHTKQD"
     gene            complement(36918..37382)
                     /locus_tag="OE968_000345"
     CDS             complement(36918..37382)
                     /locus_tag="OE968_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HCP7217662.1"
                     /translation="MTRISNITIAEQSEYCFLAIRKTIDFMVEFSEFSKQSFEKISKY
                     LEERGILSSGAPIVCFHNMDLVKLDVEVGFPVATYIDGKNEILQKIVPAQKIITAIDL
                     GLYELQDPTLEDLFSWANSNGYKLHGDIYYQYLNDINRPASEYLTKMMLPII"
     gene            complement(37811..39232)
                     /gene="nhaC"
                     /locus_tag="OE968_000346"
     CDS             complement(37811..39232)
                     /gene="nhaC"
                     /locus_tag="OE968_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HCP7217663.1"
                     /translation="MKERECRKASLFDAMIPITCLILFLSLGVLVYGSSPHVPLIGAA
                     AVAGLVAVYRLGFKWKELELSMFNSIKMAMQAILIIIIIGVLIGTWIVSGVVPCMIYW
                     GLKILSPNIFLVASTLVCAIVSLATGSSWSTMGTVGVALLGIGQSLGMPIGLIVGSII
                     SGAYFGDKLSPLSETTNLAPAMAGTDLFTHIKYMLYSTIPSLLICLVIYGVIGMKYSG
                     QALDIKQIELIRSTLDSTFNTLSPVLLLAPAIVIGLVVFKVPAIPGLIVGAVLGVLFA
                     VVFQGESMNTILDAAQNGYVSSTQIQEVDALLSKGGIMNMMSTVSLTICALSLGGILE
                     KTGMLEVVASSLLRLAKGVFGTVLCTMVTCTITNIIAGEQYLSIVIPGRMYNKEYKKR
                     GIHPKMLSRALEDSGTLTSPLVPWNTCGAYITATLGVSALTYGPYALLNIINPIVSLV
                     LIACKFKIARIEDEPETCLNFDV"
     gene            complement(39262..40326)
                     /locus_tag="OE968_000347"
     CDS             complement(39262..40326)
                     /locus_tag="OE968_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine/ornithine racemase family PLP-dependent
                     enzyme"
                     /protein_id="HCP7217664.1"
                     /translation="MYPRLEIDIEKLKHNAKLISQMCHERNIKISFVTKSFCAQKEIV
                     EEICSEGIDHIADSRIQNLKNLQDINLPKILIRIPMLSELEEVINYCDISFNSELGTI
                     KKLNELCESKNIIHKIVLMFDLGDLREGYFYEEDFFNNVREIVRLKNIEIIGIATNLT
                     CYGAIIPSRENIGRLVSIAKRMEEKFGINLEIVSGGNSSSIHLLINNNMPEGITNLRI
                     GESILLGRETAYGENINGTYQDAFKLICQVVECKEKPSVPIGEIGVDAFRNKPVYEDK
                     GILKRAIIAIGKQDINIDSLIPIDTDIKILGASSDHMILDVSNTKYDYKLGDNLEFLL
                     TYGGIMSSSTSKYVSKKIIV"
     gene            complement(40311..41720)
                     /locus_tag="OE968_000348"
     CDS             complement(40311..41720)
                     /locus_tag="OE968_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate mutase L"
                     /protein_id="HCP7217665.1"
                     /translation="MENSKVSLKIDVLVAEIGSTTTVVNAFHDINTNNPIFLGQGQAP
                     TTVFEGGDVRNGLSGAIKDLANKLSVDDIEYNDMFATSSAAGGLKMTVHGLVYDMTVK
                     AAKEAALGAGAVIRQITSGRIKRTDLNKIKEINPNIILIAGGVDYGERDTAIYNAEMI
                     ASMNLGIPVIYAGNVENQEEIRLIFEDTNYKLYITENVYPKIDLLNIEPTRRIIQSVF
                     EEHITTAPGMKYIKEMVNENITPTPGAVMEASKLLYKNIGDLLTLDVGGATTDVHSVT
                     DGSDYINKILVNPEPTAKRSVEGDLGVYVNMKNIVEVIGKENLQSELSIDIDAVIENY
                     PPIPKSKEEILFVERLTKEAVVKAMLRHSGKIRNIYGTTGKVKIAEGKDLTEVRYIVG
                     TGGALTRLPSRIEILDNMLKYNKNNELLFPKEKTKILIDNDYIMASMGVLSKKYEEAS
                     LKLLLKSLNFEEERLCILG"
     gene            complement(41720..43924)
                     /locus_tag="OE968_000349"
     CDS             complement(41720..43924)
                     /locus_tag="OE968_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892628.1"
                     /note="Presence of a B(12) (cobalamin)-binding domain
                     implies dependence on cobalamin itself, in one of its
                     several forms, or in some unusual lineages, dependence on
                     a cobalamin-like analog; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin-dependent protein"
                     /protein_id="HCP7217666.1"
                     /translation="MLKENKKLDIDYILKDLDKYKPKRRGWVWREHLENLEMGPFKYK
                     DCTKPLKKSVGLPSSKYFNNIDPQPSPVITTEIASGRFEDDIRRMRMAAHHGADHLMV
                     IRTAGQSHFDGLIEGTPQGIGGVPITRKQVRAQRKALDFIEEEVGRPINYHSYVSGVA
                     GPEVAVMFAEEGVNGAHQDPQYNVLYRNINMVRSFVDACEAKKIMAFANIAQIDGAHN
                     ANATAREAWKVMPELMVQHALNSIFSEKIGIDKSNICLSTVPPTAPPAPCLKIDLPYA
                     VALRELFSDYKMRAQMNTKYMESSTREATVTHVLNLLTSVLTRADIQSTITPDEGRNV
                     PWHIYNIEACDTAKQALVGMDGLMDMIELKDVGELRDKARELKERAVLYMEEISEVGG
                     YFESVEQGFFVDSGNYPERNGDGISRKIKGGVGEGTVYEREEDYLAPVTAHFGYNNVA
                     QYDENAIDNPSMLIDGCTFENPDKIIYIDELDDFDNVENRLKESYEYRNGTKIKPEME
                     WCADGIIMITMMLPTDKRTAEFAALEFVKKMNLQEIEVISREVMHESEGTRIEVKGRV
                     PFDIDLNNLVIPEEPKVLTDEEIRADIEEKPMKIVSATVGEDEHSVGLREIIDIKHGG
                     IEKYGIECHYLGTSVPVEKLVDAAIELNADAILASTIISHDDIHYKNMKKLHDYCVEK
                     GIRDKVMIACGGTQVTPEIAVEQGIDAGFGRNSKGIHVATFLVEKRREMSNK"
     gene            complement(43918..44292)
                     /locus_tag="OE968_000350"
     CDS             complement(43918..44292)
                     /locus_tag="OE968_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine aminomutase subunit alpha"
                     /protein_id="HCP7217667.1"
                     /translation="MKKREDDFEVRRKHLQELSDDELKERFWSLATQIVEPMIELGKK
                     NTTPSIERSVLLRMGFSSLEVKPILEGVMERGLIGKGAGHVVYKLAKSKNITVREAGL
                     LLVKGEYWDEVTCLFREGVESC"
     gene            complement(44370..45800)
                     /locus_tag="OE968_000351"
     CDS             complement(44370..45800)
                     /locus_tag="OE968_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent lyase/thiolase"
                     /protein_id="HCP7217668.1"
                     /translation="MNNSTSMKDMSYQAVMGRNNEIMKNAIGLDYSSFEQEGIGFDYE
                     KMMSETGYTLQDIEAIQSQYAVGNTPLIELKNLTKLARKCAKEGKGARIFVKDEAMNA
                     SGSFKARRAATAVYHAKQMGYKGVIAATSGNYGAAVASQAAMQGLKCIIVQECYDSNG
                     VGQPEIIEKARKCEAYGAEVVQLTVGPELFYTFLVLLEETGYFNASLYSPFGIAGVET
                     LGYELAIQFREKYKKDPDIVVCTNAGGGNLTGTARGLIKAGSINTKVVGASVDLKGLH
                     MASDNQFNKKSFTTGHTGFGIPYCTWPDRSDVPRSAARPLRYMDRYVLVKQGEVFYTT
                     ELLAQLEGIERGPAGNTSLAAAFSLAQELDEDKAIVVQETEYTGAGKHICPQLTFARE
                     NGIDIKFGNPREEIAGVNLILPERPELLKCVDIDMNKIRKSFIKNCISNNHIDNIDKL
                     SNRDIEFLMEEVKSSRDFVVDVLNNL"
     gene            complement(45793..46101)
                     /locus_tag="OE968_000352"
     CDS             complement(45793..46101)
                     /locus_tag="OE968_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-ketopentanoate thiolase"
                     /protein_id="HCP7217669.1"
                     /translation="MDAKINDWVIIHNIVLTPEERAPQVPEDTKKVSLEMWVKGFIQS
                     DASIGDLVEVKTITGRLVKGNLLKINPYYTHDYGKCIPELLQIGIQAKEILFGGVYNE
                     "
     gene            complement(46222..47289)
                     /locus_tag="OE968_000353"
     CDS             complement(46222..47289)
                     /locus_tag="OE968_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-binding protein"
                     /protein_id="HCP7217670.1"
                     /translation="MRKVRVGIWGFGAMGIGMANMILKKEGIEIVSVCSRSTSGKSMY
                     DVLGIERGERPEVIINKNYEEVFREKSVDVVLLATDSFTKKAFDKINFLLNRKINVIS
                     TAEQMAYPQADDADLAKKMDEVAKENGVSILGTGINPGFVLDLLVLALSGTCEEVTSI
                     KAKRVNDLSPFGKSVMVEQGVGVTREEFIKGVEDKTIAGHVGFVESINMIADGLGWKL
                     DKIEQTKEPIMTTVDRKSKYGEALAGNVAGCRQCGYGYVNGEVLIEMEHPQQIIPEAE
                     GIKTGDYVSIKGIPNIDLQINPEIPGGVGTYAMIVNSIPLIINARPGLKTMLDIPVPR
                     AIMGDIRNQIEVELEEESKAN"
     gene            complement(47545..48918)
                     /locus_tag="OE968_000354"
     CDS             complement(47545..48918)
                     /locus_tag="OE968_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HCP7217671.1"
                     /translation="MNEILENIDEGVHFVNKDGKTIIYNNSVQKMEKMNRHDILTNSF
                     FDIVNKMKINRSTLLEVLEKREVIKDNIQKYLDKNGKEITAINTTIPIDIKGEFVGAL
                     EISKNMTTIENLLNRNYKKNLVNKVSIRQKKGYEFDDILGESNLIKEAIAKSKKACKS
                     DASVFIYGETGTGKELFSQSIHYGSNRRNYPFIAQNCAALPESLFEGILFGTSKGGFT
                     GAIDRPGLFEQANKGTLLLDEINSMPIMLQAKLLRVLQEGYVRRVGGTKDIPIDVRII
                     ATTNESPKVILNEHKMRKDLYYRLNIIHIKIPPLRDRKEDIPLLCKKFISKYNKKLNK
                     KVVGISDEAIKILKNYDWQGNIRELENIIYCTMSMMEDEVQIETSMINLNDYYTLKEN
                     KESNNYSLNDLEDKTLSKIISEIEEKYIYESLEKASYNITKAASILGMNRQNLQYKIK
                     KYNIKIL"
     gene            complement(49893..50033)
                     /locus_tag="OE968_000355"
     CDS             complement(49893..50033)
                     /locus_tag="OE968_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7217672.1"
                     /translation="MENLMMSIITGVIASYIYDKLKSHSERPTKSGWELNIKFQKSKS
                     SK"
     gene            complement(50291..51451)
                     /locus_tag="OE968_000356"
     CDS             complement(50291..51451)
                     /locus_tag="OE968_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp27"
                     /protein_id="HCP7217673.1"
                     /translation="MKLNKTLLAIGMSVSLLIASCPTSNALSSINSIKGTNKYETAGL
                     IADKQNYDIAILINSENGLSDGLSASGLSGAKNAPILLTKKDTIPSETLKRLEKVKEV
                     YLIGGKNSIGASVQKILSDKKISINRISGTDRIDTSHKVAKEIGSVSAVKKVILTNAF
                     KGEPDAMSVASIAVRDKSPIVLTDGNTTSFATDGLETYAIGGKVSISDKLINETKATR
                     IGGVDRYDTNKQIINKFYNGSKEFYIASGTDLVYSLVGSTIAQKTPIVLVGNGSNKSI
                     LKNASKITAIGNIDDVVIKQCLNITNNVGDSNTGIVKDTNSNNTNKPSNEPSSNNPGL
                     TDKSTVYVTPNGKSYHLTKNCSTLKRSKTINKVTLKQAKSQGKIDPCNVCVK"
     gene            complement(51622..51825)
                     /locus_tag="OE968_000357"
     CDS             complement(51622..51825)
                     /locus_tag="OE968_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4236 domain-containing protein"
                     /protein_id="HCP7217674.1"
                     /translation="MGFNFRKSINLGGGLKLNLGKKSVGISAGVKGARVSVNSKGRKS
                     ATLSIPGTGISYTKTSTKKRKPK"
     gene            complement(51912..52946)
                     /locus_tag="OE968_000358"
     CDS             complement(51912..52946)
                     /locus_tag="OE968_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YHYH domain-containing protein"
                     /protein_id="HCP7217675.1"
                     /translation="MFKKKLIAVAMSITMISVGSFSYAHSGRTDSSGGHRDNKNKSGL
                     GSYHYHCGGYPAHLHNNGGCPYTGGGSSSGTATSVNNEEKQKRSVGEKGYNQGYEDGY
                     KGNYSSSNYSGDYSDTYESKYSEGYEKGKAKLEEEEKEAKETGYNLGLTGAKSNNTYE
                     KEVLKNAYDTGYSTGYNEYKTKKIEEYKAKGIEDSNKDKEKMTFEENIDSKFIDAYNN
                     AYDEIQEQLKNDYTTQGFESAIKGERFDTSTIGNVKYANWFKEGYDNGKVKLPKAKES
                     VYNQGYNEEDFSIPDEMKSIETKLKGVYDEGLEKREEEKSRNATYGVGAGTAAVVAGV
                     VYKKKKRKKI"
     gene            complement(53468..54829)
                     /gene="rlmD"
                     /locus_tag="OE968_000359"
     CDS             complement(53468..54829)
                     /gene="rlmD"
                     /locus_tag="OE968_000359"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HCP7217676.1"
                     /translation="MSVKKKDVIEFEVDKMEFGGTSLSQVGDRVIHMKGGISGQKVRA
                     GVKKVRSKKAEVKMIELLENSPLETEETCKHFRECGGCTLLSVPYEKQLEIKEKQVMD
                     LFLKQDLFGFQFLGIEGSPENKYYRNKMEYTFGDEVKNGPLTLGLHKKGKHIDIQTVE
                     ECMLVDEDFSKILVSSVEFFNEKKLPYYRTMNHKGYLRHLVVRKGIHTNEIIVNIVTS
                     SQEDFDMYEFKDMLLGIDLKAELVGVLHTINDGLADAVQCDELRVLYGRDYIQEEILG
                     LKFKISPFSFFQTNTKGAEVLYSIARDFIGDYNDKVVFDLYSGTGSIGQVMAGAAKKV
                     YGIEIVEEAVVAANENAKLNGLTNCEFIAGDVAKVVKDLKDKPDLIIVDPPRPGIHKD
                     AIRDICGFGAKEIVYISCNPKSLVVDLVDFKGYGYEIKMVKCMDMFPNTPHCETVVKL
                     IRE"
     gene            complement(54856..55578)
                     /locus_tag="OE968_000360"
     CDS             complement(54856..55578)
                     /locus_tag="OE968_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HCP7217677.1"
                     /translation="MAKKQRIDKILSNLGYGSRSEIKKYCKQGSVVVNGSEVSNPGTQ
                     VDTENDEILFNGEEVIYREYIYLMMNKPDGYISATTDKYDPTVLDLIDLSYLAFEPFP
                     VGRLDKDTEGLLVLTNDGKLSHRVLSPKKHVPKTYYAKIDGVVTEEDVEAFLEGVVLD
                     DGYKTMPSQLNILKSDDESEIELTIHEGKFHQVKRMFESVGKKVVYLKRLSMGNLKLD
                     ESLELGEYRELTDEEVKLIEER"
     gene            complement(55578..55907)
                     /locus_tag="OE968_000361"
     CDS             complement(55578..55907)
                     /locus_tag="OE968_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1904 domain-containing protein"
                     /protein_id="HCP7217678.1"
                     /translation="MPQIKIRGINENDICKISEKMINDLVEAVKCPRDYFEIECIKSV
                     AIRDGKIADVYPFVEVAWFDRGQEVQDIVARIITDSIRNNLDVESMDLAFTVFEKEKY
                     YENGEHF"
     gene            56237..57163
                     /gene="fba"
                     /locus_tag="OE968_000362"
     CDS             56237..57163
                     /gene="fba"
                     /locus_tag="OE968_000362"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-1,6-bisphosphate aldolase"
                     /protein_id="HCP7217679.1"
                     /translation="MALITTKEMFKKAYEGGFAIGAFNISDLEQLQGVLKAAKAKNSY
                     VMIQASMSAVKYAGPHTLVEMVKAASDEIGVDVALHLDHGPNMDAIKTCIDAGFSSVM
                     IDGSHFDFEENVRITKEAVEYAHSKGVVVEAELGVLAGTEDDVTSDVHKYTQPAEAVE
                     FVERTGVDSLAIAIGTSHGAFKFKGEAKLRFDILEEIQSKLPGFPIVLHGASAVDQNA
                     VATCNEFGGNIAGAKGVPVDMLRKASSMAVCKINMDTDLRLAMTAAIRKFLAENPKEF
                     DPRKYIGAGRDAIQAVVESKIDDVLGSANSIN"
     gene            complement(57298..58929)
                     /locus_tag="OE968_000363"
     CDS             complement(57298..58929)
                     /locus_tag="OE968_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HCP7217680.1"
                     /translation="MDNNLIGLIEHVENPAILCKESGEIIYCNHLIDSIFSFLDIKKP
                     RNINELDSNFDKTEILTDSKKKIAFRELRMTAHIYNMKDNNNENNIVYLFEKSLISDK
                     VIEDIIEHIDEVVVVFNKDGVIEKMNTVSDEILPFKRTEVLGRNITDLVRQGLVEEPI
                     ILNMLKVKKKIYRNIVYPDGKLIAYTAVPRWDSKGKLTGGVLTGRDISRVIKLESQIK
                     YSDISEDTEYISQSKIMDNIKKVVKRAAASDSSIFINGESGVGKEIIARTIYKYSSRR
                     DKPFIAINCGAIPNELLESEFFGYEEGSFTGAKKKGKKGLFEEANGGTIFLDEIGELP
                     MQMQKKLLRVIQENTITRIGGSKPIKIDVRYISATNISHEDLRNNLKFRQDLYYRLSV
                     IPVKIPPLRERKEDIVPLVNYFLKLYNEKYNREVEVSPKVIELLEEYSWPGNIRELKN
                     IIERFVVLSAKNVIGEDEFNMLINLDMIDNETDDLSPIVVNGIMNLNDAYKIVDQIMI
                     SKAINKYGSITKAAEVIGIYPSTIHRKIKSGHIHV"
     gene            complement(59412..60449)
                     /locus_tag="OE968_000364"
     CDS             complement(59412..60449)
                     /locus_tag="OE968_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HCP7217681.1"
                     /translation="MNDIKDLSSYKNVWIFAEQREGKIAPVVIELLGEGRKLAKEVDA
                     ELCAILLGKDVDGLAKELITFGADKVYVADDALLEKYTTDAYTKVIKDAIDEIKPEIM
                     LFGATHIGRDLAPRIASRVGTGLTADCTKLEIDPEDKKIKQTRPAFGGNIMATIICPN
                     HRPQMSTVRPGVMDKAEKDETRTGEVIALDYKITQDDIRTTVLETVKTKKDLVSLTDA
                     NVIVSGGLGLGGPEGFEMLKKLADKLGGVVGSSRAAVDAGWIDHSHQVGQTGTTVKPN
                     LYIACGISGAIQHLAGMQSSDFIIAINKNPAAPILEIADYGVVGDLHEIVPMLIEKLD
                     SVDDLLEAIKA"
     gene            complement(60468..61253)
                     /locus_tag="OE968_000365"
     CDS             complement(60468..61253)
                     /locus_tag="OE968_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012703997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HCP7217682.1"
                     /translation="MKILVCVKQVPDTNEVRINKETGTLIRDGVPSILNPDDANALEE
                     ALKIKDEHDDVTITVITMGPPQADFMLRECLAMGADDAILLSDRAFGGADTWATSNTI
                     AAGISKVGDYDIIFAGRQAIDGDTAQVGPQIAEKLDIPQVTYVQDFKIEGKDIIVQRQ
                     LEDGYELIKVSTPVLLTAVKELNTPRYMSVDKIVKAYKHDVKVWTIDDLDVNKEEVGL
                     KASPTKVFRSFTPEPRGKGEILEGKADEIASKIIIGLKQKHII"
     gene            complement(61286..62419)
                     /locus_tag="OE968_000366"
     CDS             complement(61286..62419)
                     /locus_tag="OE968_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003483287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="HCP7217683.1"
                     /translation="MLYNKEQELLRKAVRDFVSKELDTLPAEMDKTGVMPKELIKKLA
                     DAKFISSNIPEEYGGGGAGYVSYAIVMEEIARRCASTATFVTAGSSLASLPILYNGTE
                     EQKQKYLKGIATGELIGAFGLTEPGAGSDAGGQQTTAELVGDHYILNGRKTFITNGPF
                     CDVAIVIAVTDRSKGLRGTSAFIVESKWDGFSTGAHEDKMGIRGTETSDLIFENVKVP
                     KENLLGKEGQGFKIAMGTLEVGRIGVAALALGIAQGALDEAVKYTKQRVQFGKPIAKF
                     QNTQFTIADMETKVCAARGLVYDAAQKRDAGMRVAQESAMAKYYASEIANEVAYKALQ
                     LHGGYGFIKDYEIERMYRDARIVSIYEGTSEVQKMVISSNVLK"
     gene            complement(62467..63594)
                     /gene="hadC"
                     /locus_tag="OE968_000367"
     CDS             complement(62467..63594)
                     /gene="hadC"
                     /locus_tag="OE968_000367"
                     /EC_number="4.2.1.157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(R)-2-hydroxyisocaproyl-CoA dehydratase subunit
                     beta"
                     /protein_id="HCP7217684.1"
                     /translation="MEAILSKMKEVVENPNAAVKKYKSETGKKAIGCFPVYCPEEIIH
                     AAGMLPVGIWGGQTELDLAKQYFPAFACSIMQSCLEYGLKGAYDELSGVIIPGMCDTL
                     ICLGQNWKSAVPHIKYISLVHPQNRKLEAGVKYLISEYKGVKRELEEICGYEIEEAKI
                     HESIEVYNEHRKTMRDFVEVAYKHSNTIKPSIRSLVIKSGFFMRKEEHTELVKDLIAK
                     LNAMPEEVCSGKKVLLTGILADSKDILDILEDNNISVVADDLAQETRQFRTDVPAGDD
                     ALERLARQWSNIEGCSLAYDPKKKRGSLIVDEVKKKDIDGVIFCMMKFCDPEEYDYPL
                     VRKDIEDSGIPTLYVEIDQQTQNNEQARTRIQTFAEMMSLA"
     gene            complement(63594..64820)
                     /gene="hadB"
                     /locus_tag="OE968_000368"
     CDS             complement(63594..64820)
                     /gene="hadB"
                     /locus_tag="OE968_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(R)-2-hydroxyisocaproyl-CoA dehydratase subunit
                     HadB"
                     /protein_id="HCP7217685.1"
                     /translation="MSEKKEARVVINDLLAEQYANAFKAKEEGRPVGWSTSVFPQELA
                     EVFDLNVLYPENQAAGVAAKKGSLELCEIAESKGYSIDLCAYARTNFGLLENGGCEAL
                     DMPAPDFLLCCNNICNQVIKWYENISRELDIPLIMIDTTFNNEDEVTQSRIDYIKAQF
                     EEAIKQLEIISGKKFDPKKFEEVMKISAENGRLWKYSMSLPADSSPSPMNGFDLFTYM
                     AVIVCARGKKETTEAFKLLIEELEDNMKTGKSSFRGEEKYRIMMEGIPCWPYIGYKMK
                     TLAKFGVNMTGSVYPHAWALQYEVNDLDGMAVAYSTMFNNVNLDRMTKYRVDSLVEGK
                     CDGAFYHMNRSCKLMSLIQYEMQRRAAEETGLPYAGFDGDQADPRAFTNAQFETRIQG
                     LVEVMEERKKLNRGEI"
     gene            complement(64835..65635)
                     /gene="hadI"
                     /locus_tag="OE968_000369"
     CDS             complement(64835..65635)
                     /gene="hadI"
                     /locus_tag="OE968_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyisocaproyl-CoA dehydratase activator
                     HadI"
                     /protein_id="HCP7217686.1"
                     /translation="MYTMGLDIGSTASKGVILKNGEDIVASETISSGTGTTGPSRVLE
                     KLYGKTGLAREDIKKVVVTGYGRMNYSDADKQISELSCHARGVNFIIPETRTIIDIGG
                     QDAKVLKLDNNGRLLNFLMNDKCAAGTGRFLDVMAKIIEVDVSELGSISMNSQNEVSI
                     SSTCTVFAESEVISHLSENAKIEDIVAGIHTSVAKRVSSLVKRIGVQRNVVMVGGVAR
                     NSGIVRAMAREINTEIIVPDIPQLTGALGAALYAFDEAKESQKEVKNI"
     gene            complement(65674..66873)
                     /gene="hadA"
                     /locus_tag="OE968_000370"
     CDS             complement(65674..66873)
                     /gene="hadA"
                     /locus_tag="OE968_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isocaprenoyl-CoA:2-hydroxyisocaproate
                     CoA-transferase HadA"
                     /protein_id="HCP7217687.1"
                     /translation="MLLEGVKVVELSSFIAAPCCAKMLGDWGAEVIKIEPIEGDGIRV
                     MGGTFKSPASDDENPMFELENGNKKGVSINVKSKEGVEILHKLLSEADIFVTNVRVQA
                     LEKMGIAYDQIKDKYPGLIFSQILGYGEKGPLKDKPGFDYTAYFARGGVSQSVMEKGT
                     SPANTAAGFGDHYAGLALAAGSLAALHKKAQTGKGERVTVSLFHTAIYGMGTMITTAQ
                     YGNEMPLSRENPNSPLMTTYKCKDGRWIQLALIQYNKWLGKFCKVINREYILEDDRYN
                     NIDSMVNHVEDLVKIVGEAMLEKTLDEWSALLEEADLPFEKIQSCEDLLDDEQAWAND
                     FLFKKTYDSGNTGVLVNTPVMFRNEGIKEYTPAPKVGQHTVEVLKSLGYDEEKINNFK
                     DSKVVRY"
     gene            67550..68548
                     /locus_tag="OE968_000371"
     CDS             67550..68548
                     /locus_tag="OE968_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-2-hydroxyacid dehydrogenase"
                     /protein_id="HCP7217688.1"
                     /translation="MKILVFGARDYEEPVIKKWSEEHKDVQVDIYPENMTEENVVKAK
                     GYDGISIQQTNYIDNPYIYETLKDAGVKVIASRTAGVDMIHFDLVNENGLIVTNVPSY
                     SPNAIAELAVTQAMNLLRKTPLVKKKVCEGDYRWIAELLGTEVRSITVGVIGTGKIGA
                     TSAKLFKGLGANVIAFDQYPNSDLNDILTYKDSLEDLLKEADLITLHTPLLEGTKHMI
                     NKDTLAIMKDGAYIVNTGRGGLINTGDLIEALESGKIRAAALDTFETEGLFLNKKMNP
                     GELTDPEINKLLSMEQVIFTHHLGFFTSTAIENIVYSSLSSAVEVIKTGTATNRVN"
     gene            68910..69437
                     /locus_tag="OE968_000372"
     CDS             68910..69437
                     /locus_tag="OE968_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04002 family protein"
                     /protein_id="HCP7217689.1"
                     /translation="MEKMNKVTSKKTTYIVTSALFASIICLTIAYILHIPVGGNNGYV
                     HIGDAFIYLAATILPTNYAIAASAIGAGLADLSTGAAIWVIPTIIIKPILVLFFTSKS
                     DKIINKRNIVASVVAGIVGLVLYMFAEGIIIGSFTSAFVMSLLGLLQPIGSFIVFIIL
                     GMALDKLDFKKRYFN"
     gene            69464..70060
                     /locus_tag="OE968_000373"
     CDS             69464..70060
                     /locus_tag="OE968_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04100 family radical SAM protein"
                     /protein_id="HCP7217690.1"
                     /translation="MNILYTIENSIYVNITNTCPCSCVFCIRNEKDEVANSGSLWLEH
                     EPSVDEVKEAFNKYNLDDYDEIVFCGYGEPLMRINELIEVAKFIKEKSSIKIRINTNG
                     LSDLIHNKKTAILLKNVIDAVSISLNAPNKEAYNRVTQPKFGEKSFDYMLDFARDCKK
                     YIKEVAFSVVDEISPEEIEESKQLAKKLDIPLRVRHKN"
     gene            complement(70125..71708)
                     /gene="asnB"
                     /locus_tag="OE968_000374"
     CDS             complement(70125..71708)
                     /gene="asnB"
                     /locus_tag="OE968_000374"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HCP7217691.1"
                     /translation="MINLEEKYLTRKDTYMIKILEYNGHIRNWKVLCEELGIDSSLCR
                     DERERAILVEAYKTWGYDMANHMHGMFAFALWDTVEKKLFCLRDQFGVKPFYYYETEN
                     GKLLYGSSIRKIMEQPGFVKELNEDMLQIYMSFTYVAGENTFFRGVKKLMPGHYLVYQ
                     NKTVCIGRYWKPEFHPDHSKSIEEWTDEIHTTLQKIMPEVKSENETAELFLSGGVDSS
                     YILAMSDIEKTGSCGYEEERFDESKLAQQTANILGCKNSRYIITPEEYFASVPYVMYH
                     MEQPTGDASAIVFAIGCKAAAENTNICYSGEGADEFFGGYNIYHKAECYGENLKTFYI
                     GNTNIMNEGEKRKILKKYNPDVLPIEVVKGIYEETEELDTLTNMSNVDIQIWLEGDIY
                     FNIDKMSTAVGLEVRMPLTDTRIFDIASRIPSEYKVKGKENKIAFRTAASKTLPEEIA
                     FRNKLGFIVPIRIWMADDQYNKDIRDKFNSEIADKFFNIDEINEIFNDYISGNSDNWR
                     KIWMIYTFLVWYEIYFVKC"
BASE COUNT        23741 a        12400 c         8546 g        27225 t
ORIGIN      
        1 tttagacgaa cttggagcta gagtatctgc tcatttaaga cgtgaaaaaa ggaagtcaaa
       61 tcaaactaaa attaaatttt ataatgattt aacgatagat tacgaaaaaa ggttaatttg
      121 tatagataat aatcagattt cactttcaaa aaaggaattt gatatagtag aacttctctc
      181 tatgaatcct ggacaagtat ttgataaaga aaaaatctat gatagagtct ggggatacaa
      241 tagcaatgga aatagtgatg ttataatgga acacattaga aagatacgaa tcaaactatc
      301 aaaacatact ctggaaaatt atatagaaac agtctgggga gttggttata aatggataaa
      361 ataaataata tgtcattaaa aaaagctttc tttgttctta ctttatcttc actaattata
      421 gcatcaacac ttactacttt ctcatacatt ttgcttaata atctatataa ttctatacaa
      481 gataagtatt taaaaacacc tataaatacg ggttttataa ccatagttca aaacaatgtg
      541 aaccaattta gtgattatga taaaacgtta cttaatataa tcaacatact tcagcttgta
      601 cttccactta tattttttat aggactttta ttattagctg atataatttt ttacaaggta
      661 aaattaaaaa cacccataga aatactcaat aaaggtgcaa tggaaatatc caacaacaat
      721 ttagactttt gcttagagta taataataat gatgaattag gtaatctatg taatgctttt
      781 gaaaaaatga ggtctgaact aaataaaaac aacataaaga tgtggactat gattaatgat
      841 agaaaacaac ttaatgctgc tttttctcat gatttaagaa atcccctaac agttctaaaa
      901 ggttactcaa actatttaac aaaatacata ccaacaggta agcttagtga tgagaagatt
      961 ttatcaacca cacaacttat gtctgagcat attaacagaa ttgaatacta tgtagaaaat
     1021 atgagtaatg ctcaacgatt agaagattta gttgtttcaa aatctatgtc gaatataaac
     1081 aagtttatag aaaacttaga tgaaaatata tctatcattg ctaaacaaga aggaaaatct
     1141 tttacactta aaagtcaaat aaataatata aatctatttt ttgatgaaaa tatcattctt
     1201 agagtcgtcg aaaatataat atcgaatgct tttagatatg ctagaaataa tgtatccata
     1261 cttatatatc ttgaacaaga actccttacc tttgtaattg aagatgatgg tataggattt
     1321 agtaaggaat ctctaaaatt agctttaaga cctttctata gagataagac tttaaatgac
     1381 agcaatgcac actttggtat gggtctttat atctcaaaaa tattatgtga aaaacatggt
     1441 ggctctattt ctattgaaaa taattctact aacagtgcta aaattactgc taaattctca
     1501 acaagaaatt aaaatgattt tgtaagcttt cactgctatt atataaaatt tgttagttta
     1561 gaatttataa aatgtatttc aatttataac caatatatat actattttgt agaaattgta
     1621 agagttgctt caattataat attttggcaa aaggcatttg aaacaataat agaaatatat
     1681 atttaaatat gtagaatagt atgaaattag aattttggag gtgattatat taaaagtttt
     1741 gctaataata ttacattctc tcgtattgtg tttgcattgc taatgcttag ttttacattc
     1801 tgttcactgc ctttctggat atgttatttt tggtgtggaa ttagtgatat atttgatggt
     1861 cttattgccc gaaagttgag acaacaaagt ggaataggtg caaagttaga tagtattgct
     1921 gatttcattt tttcggttac aattttggtt actgtcggaa aaaatattgc tcttcccatg
     1981 tatctatggt ggtgtattgt tgcaatagca ttgttacggt tgattagtta cagtattggt
     2041 ttttttaagt atcgcacatt ttcatcgctt catactttga tgaataaaat cactggaatt
     2101 tctatctttg cgtttccatt actctatatt tgctttggtc ttgatgttgc aggaattatg
     2161 atatgtatcg tggcttttct ttcttctttt gaagaaatag caattatgat aaaatcaaaa
     2221 gaattaaatc gtgatataaa aagtatattt atgtgaaaac ttagaatttg tgacaaaaat
     2281 aatttatata ataatgagga agtaaaacat aaaaaattat ccacaagttt atgtgtaaaa
     2341 tagttttaaa gcaatagagt tgtattgtaa agcctttagt gcataaatta cattttaaat
     2401 taaaaatgat actgaaactg cttatcagca ctgcgaatta tccgcaaata gtgaagactt
     2461 tttagattta agctaaaagt tgggaaaaaa ttgagtttta aaacttacac tcttcttata
     2521 tagaaaagga gagtgttttt tatgattata aaagcaaaac aattatcaaa aatatatggt
     2581 tctaataaca ataaagttat cgcacttaat aatgtaaatt tagaaataaa ctcaggtgaa
     2641 tttgtttctg taattggacc ttctggaagt ggaaaaagca cacttttaca tattttaagt
     2701 ggattagata atcctacctc tggacaagtg ttacttgatg ataaagatat atataaacac
     2761 actgaaaaag aactatctgc acttagaaga aaatcctttg gattcgtctt tcaacaattt
     2821 aatcttttac ctgttctgac agcatctgaa aatatttcaa tgcctgtact tctagataaa
     2881 aaacaacctg ataaagaata tttaaatgaa atctcatcat tacttggaat tgcagataga
     2941 ctcaatcatc ttccccatga actttcaggt ggtcaacaac aaagagttgc aattgctaga
     3001 gcacttattg caaaaccaga tataatattt gctgatgagc ctacaggaaa cttggacagt
     3061 aaaagtggca gtgaagttat gaatcttctt ataaaaactt caaaacagtt tggaaagact
     3121 ttagtggtaa ttactcatga tgatagaatt gcaaaacttg ctgatagaaa aatttcaatt
     3181 attgatggtg ttcttatgga ggtgaaatag aaatgaagaa ttacctttca ctttcaataa
     3241 aagaattaaa aagccagaaa cttatgacta cattcatcat tatagcaata gtactatcaa
     3301 ctattatgac aactgtggtt ggacagtcaa ttggtatcct acaaaattta agaattgaac
     3361 aagcccgttc ttttaacggt gatagacatg tatcctttca ccaacttact aaaaatcaag
     3421 ttgatgacat aaagaaagat gatagagttt atcaagctgg tacttcaata actcttggca
     3481 gtagtaaaat aaaggattct ggtatctctg tacttgtaaa agagtatgat aaaacaggac
     3541 tttccaacta ccccaaatta atgaaattaa aatctggaaa tttgcctaaa gataaaaacg
     3601 aaatagcctt agatgaaaac acactaaagc ttatgggtat aaaaccaaga ctaggagtga
     3661 ctatacctat gaatttagat atttcacttt taaatgatac aataccacca tataattaca
     3721 cagctaactt taaattgagt ggtattttag aggatgatta tacaggatat gtaagtggta
     3781 tagtaaacgg tattgtaggc aaaggtgcat cagaaaatct attacctaag agatatattt
     3841 tatcctcttt ggattttaaa ataaaacagc aagagaagtt tcaagaaata gtaaatcaat
     3901 tagctaaaaa aataaatctt tctcacaatt caattcaata taattggatt tacttaaatg
     3961 ctcttaaaat acagtttgaa aaagatgaaa atagttctaa tagtgatggt atatctatga
     4021 ttatattggt atctttattt gttgccttat tggttttact ggcttctgga cttgtaatct
     4081 acaatatttt aaaaatctct gttacaaaga aaattaagga gtatggatgt ttaagagcaa
     4141 taggagctga accaaaccag atatataaga tagttatttt acaaatctta attttatgta
     4201 ctattgccat acctattgga gctgtaattg gaattatatc ttctaaaggc ataactggaa
     4261 tggtcactaa tatcttaaat ccagatatac ttctagcaaa tgataataaa gaaattactg
     4321 agcttataca taaaaacaca acagcatata tattcccatt agtattaagc actagtatat
     4381 ctttgatttt ttcacttatt tcagcattac catcagcaat atatgcttca catgtctctc
     4441 ccaaaattgc tatggctggc agtactacca aaatcaaaag aaaaattaaa cgagaaaaaa
     4501 caataaaaaa ctttgaaaga catctagcct ggctaaactt aaaaagaaat aaaggaagaa
     4561 ctataataac catactatca ttatttatga gtataacagt attcgttgca ctgagtgagt
     4621 tctctaatgt attagatgta tctaggtcag taagtaattt aaaagaagga gatttttcct
     4681 taacaaatga aatatctggt tttgataagt caatactaga taaaatagat aaaatgaaaa
     4741 acgtcaatcg cacttccttt ataaagtact ctgaatacaa acagggcgaa atagatacag
     4801 atataaattt tgaaaatagt ggtgagatgt taaaaatcat tggaattgat gagcaaactt
     4861 taaaagactt aatgccttct attacagatt ctatactaga agactttaaa aatggttcta
     4921 tctgttttat aaaaaatccg attgctattt ctacaccagg tgtaaaaact agacatacaa
     4981 atttaaaacc taaagataat atcacaatta acaaaaaaca actagatata tatagtacag
     5041 tagataaaat gttcttttta caaggtaatg gctggataaa tggtgttgat gttattgtat
     5101 atgattctgt ttataacacc ttgacaaata aaaacaagtt caaccagata aatatttatg
     5161 ctaaagataa atcaaaatta gaacaaataa gattgtctat tgaacagatt tgtgaaaata
     5221 atcctggctc tcattggata tcatatattg aatcagataa acaacttaaa gagagtttta
     5281 aacaaataga atttctagca tgggcagtta tattatttgt gggattgatt ggtactttaa
     5341 acatcattaa cacaactcat acaaatataa atactaggac taatgagatt ggagttaaaa
     5401 gagctattgg tatgagtaat agtagcttat ataagatgtt tttatgggaa ggtgtttatt
     5461 atggaatttt tgctactata tttggttcaa ttgctgggta tgtcagtgct attattataa
     5521 acatggcaac tatagaaaag cttgatttta ctaatatacc aattacttca attttacaag
     5581 ctactattat ttctatactt gcatgtatta tagctactct tattccgtta agaaaagtta
     5641 aaaagatgaa tataattgac tgtatagatg tcaatttata actattttac agataataaa
     5701 taaattaaat tatcaatgac tgtctctatt ttcttttaaa tctaactaat aaatcttttt
     5761 aactataata taagctttaa aaaaggcctg tctcaaaata gagataagcc ttttttcatt
     5821 gtcgaaataa tgaaaatata tttaacttca caaaaaaaga gtgcctcacg aattaaaaat
     5881 ttcgctttga gacactcccc tttaatttaa aatatatagt taaatgctat gccaaaattt
     5941 cacacatgct ccacctgatt ttgaattttc tattttaaca gaacctccaa gctgttccac
     6001 taattgtttt acaatgtaaa gcccaagacc agaatgtcct cctttagtct gcctagcttc
     6061 atctcctcga taaaacttat caagagcctt ttttaaatct ttagagctaa accctctacc
     6121 agaatcacaa atctcataag aaatacaatt tttttcatcc tttacagtaa tactaatatt
     6181 accacctgat ggagtgtatt gcagactgtt ggatatgata ttatcaaaaa ttcgtgtcaa
     6241 cctatccacg tcgatttgaa ttggggattg tatattcccc tgcattttca atataagttc
     6301 aacttccttt tgatgagcct gtaattcata gtcttgtacc ttttgcctca aaaattcagg
     6361 taaatttata ggaacaagat ttaattgtat atttgacttt tctaagtcag acgtatattg
     6421 catcttttgg acaagagcag cacttttttc tgtattttct cttatcactg taagatacct
     6481 atgaagtttt tcattgtcat ctgtattatt accaataagt gcatctgtat atcccaaaat
     6541 aatagaaaga ggagatttta aatcatgtgc tagagcttcc accatttcaa cacgttcctg
     6601 ctccatcttc cactgtgcag ataaagagcc ttttaattcg tctttcattt cagaaaatgc
     6661 actacaaagt ttaccgagtt cattatctga ataatagtcg atttcaaaat caaggtcctt
     6721 ttcttttatc ttcttggacg catcaatcaa tagatgtaat ggttgattga tattctttac
     6781 aaagcgctta gaaagccatc tagtaaaacc cacgatatat agaaatggag aaaacagagc
     6841 cattataata actgcaaata caaatctccc tctaatattt gcaaaggtga ttttcacttg
     6901 gtagaataga ataacagctc cctcaatctt tccattatcc cctttgattg gaacagtatg
     6961 gatataacca cctttacgaa cagttttatt gataaaatta ttaaataatt cttcttttgt
     7021 tttaaatagt tttttggggt tagtaccata taaaatattg ccattattat ccacaacttg
     7081 atatagcata tcatccccac gaatcgttct ttttaaacct tcttcattcg attgtgataa
     7141 caaagttatg tttttttcat tgatgtattt ttcaattcta ggaacttgtc gctcataata
     7201 gtttggtgga tagatatcct tatttaagga atgaatatac aaatagagag caaatacata
     7261 agtaatcact gtggcaacta tactggctat tataataaaa ataaaagtat gtctaaattg
     7321 ggtaataagg gattgatttt tcatttaata acctctctct ctttacattt tattccactt
     7381 atacccaata ccccaaactg tggaaatata ttctttttct ggtgtcacag cagaaaactt
     7441 agctcgtatt ttttttactc gttcaacaac agttgaggaa tcaccttcag aatcacaccc
     7501 ccatactttt tcatagattt gttctcttga gaaaacttgt cctgcatgga gtgctagtaa
     7561 ttcaacaata tcatactcta tttttgttaa atcaatattc ttaccatcaa ttttaattgc
     7621 acgttccttc atatataagc ataacttccc aaaatacaaa gtagatctct tgttctcttc
     7681 attgatatac tgtgaacgct tttccctacg cagattagct tcaatccttg ccataagttc
     7741 acgcagtcca aatggctttg ttacataatc atcccctcca aaggtcaacc ctttgatttt
     7801 gtcggtttct gattgctttg cacttaaaaa tataattggg cataaaacat catctctaat
     7861 tgcctgacat acctcaaatc cattcatttt aggcatcata atatccagta taataaggtc
     7921 aggctcctgt tttgataact ctatacctgc ctgaccatca taagctatca acacttcatg
     7981 tccttttgcc ttcaattcat cctcaagtag cattactagg tccatttcat catcaataat
     8041 caatatttta ctcaatataa caccaccttt ctcttatggg aaggtcagta ttaaaacaat
     8101 attcgtctac taataacttt tccttccctc ccacatttta aaccaaataa cgcctcctat
     8161 caagaatata atcaaaccta ttgctactac tataagctct atactagctg tttgcatcac
     8221 tttagagtaa aatgcctcag ttgaaatagt tccagcttct ttaataaaat aaattcctgg
     8281 aagcatacct agttttactg gccatgtcca tggaacaaat gcccatactt tttcaccaac
     8341 gctagttaat ccaagtattg ctgccatcaa aattccaccg atactaatac caatagatgc
     8401 acccataccc catgcaaaac tcacccaaag atgaatagct aatagtggaa gtgtcccaat
     8461 caccacaagt cctgctgctg acaggaataa ccatattgtt gctccagatg gcactgcaat
     8521 actcattcct atgcaaagta tcaacgtagc aataaatgtg catatagtta ggcaaaacag
     8581 aagaaaaaga aattttccca gatataatct aacacgagaa atacctacac ataaaaaacc
     8641 attaaaattt ccagcaagct cttcctcctg cactataaat cctgctaaaa tacctactcc
     8701 aataggaatg atgaatacag tccatactgt aaaaaatcct tcaaaagcaa attcttgtgt
     8761 acttccagat ttagttgtga gataaaaaac cacacataat gaaaaaataa taggcataaa
     8821 aagagtaagc cactggacag ctgtcctctt tgctcgaagc cattctgatg ataatagctt
     8881 tatcatttgt catccctcct attgaaccaa gctgcagtaa gtgctgttaa tactataaac
     8941 acaaccaaag aaacaacaat cccaatagga atcactgaag tattcaaaag tgggtctcca
     9001 gcttctaata tagtaccgtt aggatgtatg ttgatgattg ggcataccat tctaactgcc
     9061 caactccaag gtactgcaat ccaaaatggt tttgtcgcag caaggacacc aaatatcata
     9121 cctaaagctc caactcccat acttaggaac atacctttcc atgtagctag ccatagctga
     9181 agtggaagta tagcaagaga aacaacccag catacaatac ttgcccctat aatctgtcca
     9241 aaaggaactg gaccagcttt caatattaaa ccagttataa ttgttacgac tattaaaact
     9301 agcgttgaaa taaaactgta gactgccata gctataactt tattaatcca aagtgtcata
     9361 ggagacacat tgtgtgtacg taaagcacga taatttccag cttttttttc ctggaaagct
     9421 accaaagtag caaacaatgc aaatccaata ggcagaaata aaaatgacca ccagttaaaa
     9481 attaatgcta aaagactttg ccacgcccaa gaagttgttt gagataatgg attttgcatg
     9541 agtgttgatt gcattataaa tgcatatgct gcaaaagaca ctgggaaaaa aacaataagt
     9601 ttacccataa atgttctttt atactttaaa agttctgatt gtaaagcatt catctgtttt
     9661 gtcctccttt aagaataaca tctgtaaaaa attcttctag attttcatta gggtcaggca
     9721 ttccttgaaa taatagtcgt cctccattta taattcctat attatctaca acttgagcaa
     9781 cctctgatag aatatggcta gaaagaatta cagttatacc tttttttgga aaagaagcaa
     9841 tcaattcacg caattcttga atgccaaagg ggtcaagacc attggttggt tcatctagta
     9901 ttaacaactc tgggtcactc aaaagtgcaa tagctattcc taacctttgt ttcataccca
     9961 tagaaaattg tgaagctctc tttttacctg tatttttcaa atttactatt tccaacactt
    10021 cataaatttt atctttaggt attcccaata tttttgtatg tactaacaaa ttttcctctg
    10081 ctgtaaggtt tccatacaat gcaggggatt ctattaaaga acctattttt gcaagagatt
    10141 ctcgtttcca aggctttcta tcaaaaataa tacgaccatt tgttgggcga agaagaccaa
    10201 caagcatttt aagtgttgtg gactttcctg ctccatttgg tcctaaaagt ccatatatac
    10261 tatttcgttc aatttgtaga gaaacattgt taactgccat ttgttctcca tatctttttg
    10321 ataagttttt tgtttcaaga attaaatctt tcatattaat ttctcccttc ttgtaatacc
    10381 ttaaatctgt tactaagaga atactaacat gaaaaaataa caattctata acacctacta
    10441 attttaataa aatttaaaat aaaaaataga gttaccaatt ttattttggc aactctattt
    10501 aagtttatgt tttacagtta tattagattt aagcttagtt tcattatcac actaacttca
    10561 aatttactct ataatcctta aatcaaacac taatttatta atcaaacact aatctattaa
    10621 tttatatttc tttagacatc taatatagtt tgctactaaa taataattat ttatatcata
    10681 tttatctaat cctttaaaag aagttatttc atcattaagc tcatcactac cttctacaaa
    10741 aacataacct gtttcaaatt ccatacctac aataatctta cagccactat aaatttcctc
    10801 ttgagtatcg tacaattttt ttgcatttcc ttcatttgga attgtaaata caataggttt
    10861 taattcttta tcactggaaa tcttttgtga aaaaggcttg tttaacttaa tattattgat
    10921 aactacatgt ttaaattcct ctgaagtttc ttctactatt acatattttc gctttaaaaa
    10981 ctctattatt tctaaaacag acttagaatt tacttttaaa atacttttat atttttcata
    11041 taaagatttc cactgttcaa ttttttcctg tggtacttct tggatatgtg tacttatttt
    11101 ttcttgagat atttttttca attaaactct cctttcaata cttaaatatc cttataaatc
    11161 tcacatgact aaagttacaa ggttcctact taatagaatt ttgcatactt aaatatgtct
    11221 tattaattct ctacaggata tctccgtagt tcctacgatt cttacataag ttacttattt
    11281 taaattgtta ttagttagat tataaaaatt atttatttta tcactaatat aatactctta
    11341 aaaactttac aaatcaattt aaatttgcta ccttttattt ataacaactt atagtacatt
    11401 tctcctatgc ttttcaatat attactttta aaaggaggtt ttcattatga ttttaaatag
    11461 agctgagctt ttccgaggat attctttaaa tagatttaac gagatatgca atatattatc
    11521 agtaaataaa attaaatata agtataaagt gaaaaataat gcttactcta aaaaaccttt
    11581 ttttaatgaa ataacacttg gcaatttagg ccaaaaggaa gatttctctt atgagtactt
    11641 aatttatgtt cataaagacg attatgaaca ggcagagtct ctaataaatt ctaagttgcg
    11701 atagattatc tataaaacat gacattctgt tgtcatgttt tatatgttat tatactttca
    11761 aatatgctac tatattttca aaattgtgtg ctttaaaact agcttttttt agtaatttaa
    11821 agcttaaaac taaggagact cgttatatga aaataaatat aaaatcaaag ttaagtgaat
    11881 ttattaaaca gaacaatctt tttgatgaca gcagaataat atcctatctt cctaatataa
    11941 caatagaaac agacaaaata aaaactataa tgattaatga ggttgtccca actaacacca
    12001 atgacgattt ttatagtgta gataaagatg ctgattattt aaaaactact attcctttat
    12061 ttgacagtgc aggaataaaa gtatctaaca taaatgatat cctagatatg ggtatctata
    12121 taactaatgc agtaaaactt cctaaatcag aatatacaat aactcgtgat acaattaaat
    12181 tacatatgcc tattttagaa gaagaaatta aattatttaa aaacctagag gtagtaatgt
    12241 taatgggaga tgttgcaaaa aaatctttta atatgattac taaaaagcat ataaaaaaga
    12301 atgtcatccc ttccatttca acatataaac ttcgtaataa tgaactttat tatgataatt
    12361 taagagtatt tccatcatat attatgactg gtggaaacat actgattgaa aaatcaaaat
    12421 ttgaaatggc atcagaagat ataaaaaaaa tgttcgagat tataaacggt tgatattaca
    12481 aaataataaa aactaatata aaataaaaag tgcctcaaaa acttctattt atgaggcact
    12541 tttattttat attagtgtaa ctatatacta ttaacataat ttattattta tattgttcct
    12601 tttaatctct attccattta gtctaggtaa cattactctt tacaagatta ctttatattt
    12661 cttttatatc tctaacgttt ttatttaata aaacaattat taatacaagt caaatatatc
    12721 tatttatcta aaaatatatc ttttacagta atatctggat ggtgatactt cttcctattc
    12781 gttaaaaaag atttttttac attaatagcc tcttttggac accagtgaaa acaagctagg
    12841 catctttcac actcattacc ccactttggc tttttatcaa ctatacttat attctctaca
    12901 ggacaaaccc ttttacatgt cccacatcta ttacatttat tttctgcaaa aaatttagta
    12961 gttgcaattt gcatattctt acctactaaa cgaagtacaa cactatctat atgtgacttt
    13021 aaattgtttt ttccttctat atttccaatc tccaagttat tgatacattt tgcaatctca
    13081 gctaccctat tagtctgatt tttcaatctt tcttcttcaa catctggagg tgttatcaaa
    13141 gcatttccag gcatattgat taaaaaacca gcagataatt ttttccccct ttttttaagt
    13201 aacttatcta tagtaaataa actatgtcca gctaccccat tacaagtggc aatggcatat
    13261 atatgagtat taatattaaa atttaatttc tctacaaaag actttactat atcaggaaca
    13321 tcagcaaaat aaacaggaaa aacaattacc aatatatctt catttatgtc tatattattt
    13381 tcttttctat gtatagctaa gggtataact tctttacttc catttaacgt ttcttttaaa
    13441 atatttgaaa ctactagcga atttcctgtt ccagaaaaat aataaatctt actattcatt
    13501 cttatccctc tttctatatt tctacatcat caatagttaa aaagtctctt aaaataggat
    13561 ttatatttac tttccaattc tatccaaaat atcagtaaac aaaggcaatt cttcatcaga
    13621 gatagattta aatgtctctg ttgcatatat acttgcaatt tcatttaatg gttcttctaa
    13681 ttctctacct aaatctgtta ggaatatttg aaacttacgt ctatctttaa catctacttt
    13741 acggacaatt aatcccttat ttttcataac atctaagatt cttgtcgtat tagatttatc
    13801 cttacatgat ttttcacata aatctatctg agaaattcca tcttgctccc atagaaacct
    13861 taataacgca taatggtcag ttgttatatc atatccattt tgtttaaaca tcttttttaa
    13921 atcatctttt acttttaacg aagtacttac taacttagtt gtagcttcat atagtttctc
    13981 aaaatctttc attttacctc catttaaata atcccttgct cctcccatct atcaattatt
    14041 cccttatatt gctcaatatc tttaaaagcc attggcttta aaacagcatt tatagcaata
    14101 aaattataga tttgagaaag cacaggtgga tttttctttt cctctatgca ataaataaat
    14161 tttttagata ccttttgtat ctttgattct actttttcag ttataggatt ttgattaaat
    14221 ccagttttta tagataaact accacaaaca taacctcccg aatctaagac catggatttt
    14281 ataaaagaaa ttgcttttga accacgtgca ttttcatatg tagtaactgc tatacatggc
    14341 ttacgataca ataatctttc aagcatcata tgtgctctat ctgtaaacac cttgaaaagt
    14401 ccagttacac tacttccata agttgggcta ccaaatataa caccatcact cttagtaatt
    14461 atatcatgaa tatactctac tttatcattt tgattgatac acttgcccat tttataacaa
    14521 tttaaacaac caatacaata tgatggattg acctcactta aatcaaaata attaattttt
    14581 acatctggta ttaatctttc tatatcttta tacaagtaag tcaaaacttt tgatgtagct
    14641 ccattttttc tagggcttcc atttataact gtaattatca tttctatatc tcctttttag
    14701 ttgttatatc aacaataagt atatcaacta tatttttagc tgtcaatata aaccatttat
    14761 ttaaagctat acttacacag cttaaataaa agttttattt aactacatgt gcttatttaa
    14821 tcaactataa atgaattatt tttaataatt gacaaactaa attaatgata atatacttta
    14881 tgtattacaa atgtaagtag aaggaggtat agtatgaaaa agttaccaca tatttcagaa
    14941 gcagaatatc aagttatgaa aattatttgg aaatatgctc ctatcagcac tactgaagta
    15001 attgaaaagt tggtagaaac aagtacatgg agtcctaaaa caattcaaac aatgttattg
    15061 agattagtta aaaaaggagc tttaacatat gaaaaaaata gcagagtatt cgtttatact
    15121 ccacttgtta aagaagaaga atacgtagct acagaaagta gttctttttt aaatcgtttt
    15181 tataatggta ctcttaattc tatggtacta aactttttag aaaatgataa actatctgaa
    15241 gatgatattg aggaactgag agaaatctta aataaaagga cgactaaggg ggataaataa
    15301 atatgtatgc cccattcttt atacgatttt tactcagtac attaacctta tcaatattaa
    15361 ttgttgtaat tttacttgcc aaaaaagtat ttaaaaaaca tatttctgca aagtaccaat
    15421 acaatattgg atttatattg cttataatgt taataattcc atttgtccct cttaaatata
    15481 ttaatcttgg aaatgtattt aactatttat atacttttaa tcaacttgga agcagtacta
    15541 ataggacttc tatgataaaa aatagttcaa attctgtaat taataactca aatgcattaa
    15601 acgatttttc agtatcccta aatcaagtta attttgatag tttaaatatt ttattactaa
    15661 tatcatggat aattggaatt ttaatcatga tagctattac tattcattgc aacattaaaa
    15721 taaaaaatat gaaaaaatca atacaaattt taaaagatga ggagatagta tttatatttg
    15781 aaaagtgtaa aaaagatatt ggtataaata aggattttat actatgcaaa tcacctatta
    15841 taaatacacc tattacattt ggatacttta aaccacacat tatattacca gataagtcta
    15901 tatctaaatt atctttaaaa gatataaaat atatcttact tcatgaatta caacatttta
    15961 aaaataaaga tatactgata aattatataa tgtgctttct tcaaatatta tattggttta
    16021 atcctcttgt atggtatgca tttaaagaaa tgcgtataga ccgtgaaatt gcatgtgata
    16081 tttcagtttt aaaaaagctt aataaagata gtcatataga atatggacaa actctaataa
    16141 actttgtgga taatatttca agaccatcaa atcttacact tacatcagat attggtggtt
    16201 caaaaaaaca aataaaaaag cgactattga agataatgga ttttcataat gaatcaaata
    16261 cgttaaaatt caaaagcatt ttaattttta cattgatagc tttaattgta tttggaaata
    16321 ttcccaaact atctattatg gcagatatca acgaaaaata tagacctaca aatgaacaaa
    16381 ctgtgtacga ggacttaagt cagtatttta aaggttttga tggaagtttt gttatgtatg
    16441 atttaaaatc caagcaatat catatttaca ataaagaaaa aagtaaaaca agaatttctc
    16501 caaattctac ttataagatt tatagtgcct tattgggatt ggaaaatggg ataataacaa
    16561 gaaataattc acatatccct tgggatggaa agcatcattc taatagttct tggaatgaag
    16621 accaagactt attttctgct atggaaaact ccgtaaactg gtactttcag actctagata
    16681 aaaaaacagg gctaaaaaac atacaaactt atcttaggca aattggatat ggcaattatg
    16741 atgtttcagg tggtatctca aacttttggc tagaatcttc attaaaaata tcacctattg
    16801 aacaggtaga attacttgaa agtttttata caaataagtt taaatttgaa gataaaaata
    16861 tagaaacagt aaaagattca ttgttaatat caaaaaagga tggggtatca ctttttggta
    16921 aaacaggcac tgccaatata aatggaaaag atgtaaatgg ttggtttata ggttatgtgg
    16981 aaaaaaatga aaatacttat ttctttgcta caaatattca aagcaaagat tattctaatg
    17041 gtagttcagc atctaagata acattatcca tattaaatga caaaaaaatc tataatcctt
    17101 aatatattta ctgtacattc taaaaaattc acataatttt catattaatt atcaattaaa
    17161 ttcatataca aggcttatta tataaacata gaagatagta aaactagctt aaaaacataa
    17221 tataataccc tatacaaata gtggcaactc tccctcacat cctcaattgt tgccactatt
    17281 taattttttg tatgaagtta aatatatttt catcatttca acaatttggg tgcaatacaa
    17341 tctctatttt gaaacaacct ctttaattgt tttagagttt atgaattatt tctcatactt
    17401 taaaaagatt gaattactct tgataatctt cttttgtagt cattacatat cacctactac
    17461 tcaacacata ttctttgacc tatttttaca tccttgttta tatccaaaat atttaccttc
    17521 ttaccatctg gaaacaatac cattgtcaaa gtagactttc ctaattcatg tattctcttt
    17581 aaatcaacat taacaagaac gtctccctgt ttaaccatat ctccttgttt aacagcaaca
    17641 tcaaagccat ctccatttaa tgcaactgta tcaattccaa catgaattaa tacttctcca
    17701 ttagttcctt taatcccaaa tgcatgtcca cttgaaacca ctgtttctaa tttacctgaa
    17761 ataggagaaa caatttttcc atctataata tcaatagcaa aaccatcacc taacattttt
    17821 ttagaaaatg tttcatctgg tacattttct aatgcaacaa ttttcccctt agctggagac
    17881 acaaagtttt cattattttc attaaacact aattcttcgt cttcatcttc atttatagct
    17941 tctttaggca ctccaaataa acatgttaca ataaagcaga atgcaaccac aaatattgat
    18001 actaataagt atgtgattaa attatatcca tcatagatat acattaaata agaaggtaaa
    18061 actgctaatc catatgaatt agattgaata tgtaaaattg ataatattgc tgctcctaaa
    18121 cctgaagatg cacacataat aatcaaaggc tttaaattat atcgaagctg aatcccaaat
    18181 aaaacaggct cacttatacc aaaaagttga gatagcattg ctccaaccgc agtttgttta
    18241 acttgattat ttttagattt tttcataaat gctagacatg ttccaatatt cgcaaatcca
    18301 tacattgcac aaagagtaat aagggcatta aatcctgtat ttgctaatag tgatgtttca
    18361 atcattacat aagtatgatg taagccagta ataacagcta atggatatgt aaatccaata
    18421 ataaatcctc caattcctaa aggcaaatca atcaataagc tgatgatatc aaccattttt
    18481 aattctattg tatgcattat agggcctaca cctaacaaaa taactaacat tgttattagc
    18541 ataacaaaaa atggtgtgaa aataaggtct aatacattag gcatatgttt acggaaccat
    18601 ttttcaagat tagctccaat aaatgctgta acaatagctg ttaaaacact tccttgacaa
    18661 cctacaatag gaataaatcc aaatgccata attgcttcaa tttcatttga tgggtcagca
    18721 acagaatatg cattaggaag tattggggaa actaacataa gtccaataac aagtccaata
    18781 acaggtgttc ctccaaatac tttaaatgct gaccatacaa taattgctgg taaaaaagca
    18841 aatgctgttt ctgtaagaac cgaaacaagt gtctgaatat acaatggaat atttgcagaa
    18901 gacattccaa ataatccaag tacattatca ttaaacaaac aaccctttaa tcccaagaat
    18961 aatcctgttg ctgcaataac tggaataata ggaacaaata tatctgctag agttctcata
    19021 actttcttaa atccagtttc attattttta actaattcat cttgttcttt ttttgataaa
    19081 gtttttaatc ccattttttc aacttctgca taaactttat taactattcc tgttcctaaa
    19141 ataatttgat actgtccaga agtaaagaaa acccctttaa cctcatcaac tttttcaact
    19201 ttcttatcat taataatttc tctatcttta accatcactc ttaatcttgt ggcacaatgt
    19261 gtaatagaaa taatattatc ttcaccaata attttaataa gctcatttgc tattttatta
    19321 tatttattca tttttctacc tcactttcaa taatactgca tgaaatggtt tcaaacgcac
    19381 tgttttattt aatagattta tatcatctaa attttggaat acaatatcat atttttcttc
    19441 tactcttatt tctacaggtt tatcagaaaa attataataa caatcaataa ctaccaaatc
    19501 taattgcctt ctatacgcaa taatatcatc actttctata tcaataggtt ctattgaacc
    19561 ataaatcaaa caatcagaat actcactatc ttgtctcaac tttatcatct ttttataaaa
    19621 ttctaaaata ctctctgaat tgttaatctg actctgtgca ttaatatctt tataattttc
    19681 aataaccttt aaccatggtg ttgtatctga aaaacctgca ttttctttat ctgcccatgg
    19741 aaatggcgtt cttgcattat ctcggcttct taaattcaca aattctaacg cttcttcttc
    19801 tgagtaactt tcatctattg aacgatagta ttggtcaatg ctagataaat cattaaaatc
    19861 atttatggta tctcttttaa aatttgtcat tcctaattcc tgtccctgat aaataaatgg
    19921 ggttcctctt aaaaagaaat acattgctcc caacattttt actgcatcat cattcctttc
    19981 gtattgcaaa agatactttg ttgtagctct tggttggtca tgattttcaa taaaattagc
    20041 tgcccatcca tgttcctgaa catacatttg actatctaaa atgcattttc ttaaatctgg
    20101 aattgtccat gaaattcttt taaaccactc actaccagaa gcaacatcta agtcagcatg
    20161 tttaaagtca aagaccattg aaaagaaacc atcttctcca ataaaatcac ctagctggtc
    20221 atagctaata cctgctgctt cagcaacagt catacaatca tattttttaa acgtattttc
    20281 ttttaattca taaagcattt tttctattcc aggctgattt ctaactgttt ttgtacattt
    20341 aacaagacca tcaacaccat cactttctaa actttgaaaa cttaaattct ttttgatgaa
    20401 tgtaatagca tcaactctaa atcctgccac tcccatttga gaccaggtat taatcatttg
    20461 gtaaagttca cttcttaata ttggattttc ccaattaagg tcaggttgtt ttttaccaaa
    20521 agaatgaaaa taatattcgt ctctattctc taccttttcc caaacacttc caccaaaaac
    20581 agacctccag ttatttggta aatcgtttcc ttttttaaaa atataataat catgataagg
    20641 actttctgga ttttttaatg cttcttgaaa ccaaggatgt tcatcacttg tatgattaag
    20701 aactaaatct aatataattt tgattcctct atctttactt tctttaatta actcttttaa
    20761 atcttccata cttccaaatt cacttgcaat atccaaataa tcactaatat catacccatt
    20821 atcgtccata ggtgatttaa aaattggaca taaccacaat gatgtaatac ctaaattttt
    20881 taaataatct aaacgagaaa taattccctg taaatctcca attccatcat tattactatc
    20941 ttgaaagctt cttggataaa tttgataaac gatttctttt tgccaccatt tcttttccat
    21001 aaattactcc tttttatatg atatttcttc tttttaattc tttataaatt ccattatcga
    21061 atatgtcctc acatatagat gtcgctatat ctttaagttg ttgatgacta tttttcattg
    21121 caattgtaac gtctgatgct tgaaacatga caacatcgtt ttgaccatca ccaaaacata
    21181 tggtttcttt ttgagttact cctaatcttt cttgtaatct cttaattgct ttgcccttat
    21241 gaaaatcttt ttgaataatt tcataatact gactagaaat atctctctgt gctaattcca
    21301 ttttatcttg tagtatattt ttcacttcgt caaatacctt ttcatttgac cataaacaaa
    21361 ttttatgtat atcttgtgac ttatactctt caatgttatt ttcatatgtt attttttctt
    21421 ggatatgttg tttatttata caagaattag ttcctttcaa ctgattcatt gtttcaaata
    21481 tttctttggc tttttgattc atgaaaactt tttcctgact ctcaatcgaa aaagcaactt
    21541 ctctcttttt taataaacaa acaacttcct ttatcaatct ttgattaaaa gattgattat
    21601 aaagtaattc accatgatat tgaatgtaat tacctcctcc tgcaatatat ccatcaactc
    21661 ctaatgataa aacatcatct tgtattgtac ccatacttct tccagtacaa ataacaacac
    21721 tgcaatgatt cttttgacat aaacgtatag catgctttgc agattctggg attccatata
    21781 cctcatctct aagcgtacca tctatatcaa gtattaataa tttgtacaat ttcatcttcc
    21841 tttcttacta tcaaaatcat aatagcattc aaaaaaaaag atatcaatat tttgatatct
    21901 tttaaaaaat atgttcattt ttagcacaaa ttttcatttt cggggaatat gttcactttc
    21961 taaatacatc ttgtatttaa tataaagcag ttcaattaaa ataaaataag gtgttgttac
    22021 atcgtagtcc agttgtttat ctacagaaat agatatagat tgaatataca ggttttcatc
    22081 acataatctt gctaaaggat tacttatcat ttttgtaata gaaaccatat aaattccttt
    22141 cattctcatt tctttagcaa aatcaataat tgtagatgca tctccattca atgaaataaa
    22201 gaaaatcata tcatctgttt ttataaaatg attaagtgcc tgaatcatat cataaccata
    22261 aacatcatat ataattttcc ctgttggtaa gaaaatcctt ttcatctctt tagcaactct
    22321 ttcctgagaa taaccttctc caaagacgat tatacgattt gcctttttca ttctttcaaa
    22381 cataatcgaa caatccttct tctctatatc atctatcacc ttattataac aatccattaa
    22441 ttggtgttta ctttgatttt tatattctac ttctgtttca tttaagcgta taataactct
    22501 taattcacta tatccaggta attgtagttt ttgagcaaaa cgagaaagtg cacttgtaga
    22561 tatatggtat ttgtctgcaa attcatctat agaaagttta atacaatctt ctttatgatt
    22621 aagaatacac tcacagatat acttatcatt tgctgtaaat gaattataat atttattgaa
    22681 aagtccttca attttcattc ttttctcctt ctatactcta tgtaattcat atgaagcaaa
    22741 tctaatagag cataaaatgc tcctacgact tcataagata tagcttgtaa tgtatcaagt
    22801 ttttgcgttt caacatacag attatactca caaagtgttg caattgtatt attatcaagc
    22861 ctagttaaag aaatcgtatg tatatgattg ttgataaatt ttgcaatttc aattcctgct
    22921 tttgtttctc cagacaaaga aatgataata aataaatcat ttttttgaaa tgattctctc
    22981 ataaattcaa tttcacctat atcaaataag tcaataacac atttacctac tgaaagaaat
    23041 attctcttta tttcttgagc taaacttttc tgttcattac ctgtcccata aatataaatt
    23101 gtttctgcat catatattat tttacaaata tcttgaaatg atattttttg taattcattc
    23161 attaatagtc gataattctc gcaaacatca tgaaaattat tatcattatt aacaaattct
    23221 agttgattat ttttaagtaa atactttaaa tcagagaatg aatctaatcc aatttttcta
    23281 caaagcctta ataaagtagc tctagaaaca ttacattcat ttgcaatttt ttcacacgaa
    23341 aaattacggt attctctttg acaaatcaat atttgtttaa taataatttt atcattttca
    23401 tttaaattat cataattttg gttaactaac gattctaatc tcattttttc cactccctaa
    23461 atattatttt aatatacatt agttgctttt tctagggaag agttttaaat aataaggata
    23521 aaataatcat ttgattttat ttttattaaa ataaaaataa cctgctaaaa gcaggcacca
    23581 aaaagtactt atcctttcga acatgtactt tagatattgc tttcttcgga agcttcatct
    23641 cttcatactc taaaatatag ttttttctaa ctcaaaagta ttttccatgg tagaaattac
    23701 tttaattcat ctgccattta ctttttatct tatttaataa ttactattac ttgaatattt
    23761 acttctttaa gtaaatttca tagttaacaa agctaaaact attattatag atgttaaaat
    23821 acaaaattgt aagtattgtt ataaatatgc ttacagctac aaatatacat gatatattaa
    23881 aaagaagctg taaattatta tcatacatac aagcaactat gcctctatta atccatgtta
    23941 atttttatta tttaatacaa ggagttccat gagacataca tatccattca tattttaaat
    24001 tatccaattc tcttatagat ttcaccatct ttttataatc ccaattccat ggattaggat
    24061 aaggaactat atttccattc ttatttttga ctaaatcacc tgcaaataat acagcttcaa
    24121 aaatcatgca gacatgccct ggagtatgac caggagtatg gataattttt atattcccaa
    24181 tctgcatatt ctctccataa ggttcaacat ccttaatgag ccttctggaa attgcctttc
    24241 caataaactt cttaaaccca ggtctatcct tctctcctat aataaaaggt atatcctcta
    24301 catgagccca tacttttgct cctgtttttt ctttcaataa tttaatatta gatatatggt
    24361 caacatcatg atgagttaat aaaatatgct taatatctgt aagtttaatg ccaagtgttt
    24421 ttaattcttt aattatattt ttccccataa aaggaagacc tgtgtctata agaataattt
    24481 ctttatcaaa cacaataaaa caatttgagc cacgagtact atctaacatt aatacatttt
    24541 cttttatctt cataaataaa ttccccttat ttggtatttt acctatataa ttaattaata
    24601 aagttataaa tagttataat acttgatatt aattttattt tttattaaag tatactatag
    24661 gtatacaagt attatattta cataagtata ccatcagtat acttttttat caatagaaag
    24721 gaataattta tatgtcagaa ttatcaaaaa gagataaaga aaaaatacaa agagaaaatg
    24781 agattattga taaagcagaa aaattatttt gtcttaatgg atttgataat acaactatga
    24841 atgaattagc aaaagaagtt gaatatacta aacgcaccat atacaagtac ttttcatgta
    24901 aagaagattt attctttgct gttgtcttaa gaggatataa aagactttgg gataatgtta
    24961 aaatagaaag tgcaaaaggc aaaacagggt ttgaaaaaat aaaactttca tactttgctt
    25021 ttcataaatt ttactctgta gaaccttctc tattatgcct tatgggaatg attggtattg
    25081 taaactctga aaaatcggat actgatatgc tgtttaaaga aaagtttttt tcttttaata
    25141 aatttatgtt tgatgaaata caaggaatgt ttgaaattgg aaaaaatgat agaagtatta
    25201 ggcatgatat tgaaatacct actcttatgt attcatcaat atttacactt acaggatttt
    25261 ttaatttact atctgtaaca ggaaaatcat acctgaacaa ctttaatata gatgaggaaa
    25321 aatttattga aacaactctt gctcttttaa tagattcaat taaagcataa acctaagttt
    25381 ataaattaaa gtttatatac ttaaatgata attttttcta tctctaatat aaaaaatatt
    25441 aaacataaaa ctaataactt agttaatgga ataactaaat tactgaaagg attaaaagta
    25501 aatggctaaa atacttcttt tagaagatga tgatacaatt acatttggaa taaaaacttc
    25561 ccttgaaaag aaaaatcaca ctgtatgttg ttataatacg attgctgaag ctaaaaaaaa
    25621 ttttgataaa actattgatt taattctgct tgatttaaat ctacctgatg gtattggata
    25681 cgagttttgc caatatgtta aaagtataga agatactcca gtgatatttt tgacagtccg
    25741 tgatgatgaa aaagacatta tacgtggatt agatatgggt gcagatgact atgtggttaa
    25801 accgtttttg ctctcagtac ttcagtccag aattaatgca gttcttagaa gaactcattc
    25861 aaatactaac aatactatta catgtgaaaa tataagcttg aataaggttg aagtcaaagc
    25921 atatttagat aatgttgaag tacctttgac agcaggagaa tataaacttc ttctaagtct
    25981 tatggaaaat aaaaatagag ctatgactcg tacaaagtta ctagaaatgc tctgggatgt
    26041 agatggtaat ttcgtaaatg ataacactct tactgttaca ataaaacgtc ttagagaaaa
    26101 attaaaaaat ccaccttgta taaaaacgtt aagaggcata ggatatagaa tggaggacag
    26161 ctagtgaaaa ctccaagaaa tatcaacagt acagttgttt ttataatatt ctgcttaatt
    26221 gtaacttttt tattgagtgt aattctaaca actataactt cttttaatga atacaatgta
    26281 ctgtctaagg ctcttggtgc atcatatgag tacaatccta agtctacaga aagtatacta
    26341 aaatcactga aaaattctag tgataaggat tttaaaacag gaaatgaaat tttatcaaaa
    26401 catggatatt ctaaaagtac attttggagt aaaaactttt tttattttct agtgatatcg
    26461 tttggtataa tttcaacaat ggctacagtt atatatataa tcaaacatag aacaaataag
    26521 caaaaactga gtagaataaa caatcttact caatacttag aagaagtgaa tttaggaaaa
    26581 gagtctgtac ttttacgatg tgaagatgaa ttttctcacc ttgaagatga gatatataaa
    26641 acagttgggg aacttcgttg ttcaaaagaa tttgctttaa aagaaagaca aactctttca
    26701 gataatcttg cagatattgc tcatcaactt aagactccaa ttacttctat gtcacttatg
    26761 gcacaattac tttcagaaaa ttgtccagat gaagaaatag attatattaa cagacttaca
    26821 aatcaaatct caagacttga gagactagtt tcatctttac ttacattatc aaaattggat
    26881 gcaagtactt taatatttga aagcaaactt atagatgtac attctcttct tacttatgca
    26941 attgagccta tagaaggttc tttaagagaa aaacatcaga catttactat cgaggcttct
    27001 ccttcggtag aatttgaaat cgatattaat tggactttag aagctctttt aaatattctt
    27061 aaaaattgta gtgagcatat agaagatggt ggatatatag ttgcttatta tagtcaaaat
    27121 cctctatatg ttgagattat catagaagat aatggtaagg ggtttgctca ggaagaactt
    27181 ccatatattt ttaatagatt ttatcgtggt aaaaatgcta gtaaggacag tattggtata
    27241 gggcttgctc tatcaaagtc tattatagaa cgtcaaaatg gtactctaca tgcagaaaat
    27301 tgccataatg gtggtgcaag attcataatt aaattttaca cataaaatgc tggattatag
    27361 gtaaaatacc tataatccag ctatatctat attctatgtt atctattgtt ttagtaatat
    27421 acttctattt acatttaagg ttttattaaa caaacaactt aactatccct atacttgtaa
    27481 gtagtcttaa atcgaaacct ttaaataagt tcaaatagat tttgtttata ttgtttcatt
    27541 ttttatagat tctactatat tttcattctt caactgcttg tatcctgtca tatatgatgc
    27601 tattacaata aaaagtatca atatagtaaa acctattatt gtagatatag gtgcaaatgg
    27661 taaatactct ataaaatata tttcatttat acgtagaaaa gcatacacta ttcctatttg
    27721 cacaggaata ctaagtagta atggtgtaat tcctaagaat aaaccttcca aaataagcat
    27781 cttttttatg ccttctggag ataatccaac agaacgcaac atagcaaact cttgtcgtct
    27841 acttctaata tttcctgaca ctgtagcaag tacatttgat aatccaatca tagccaataa
    27901 acctgtaata aagcctacta ttaaattcat ggtctttatt ccactagcct tttgtttttc
    27961 actttctaaa acatcctcaa tactataatc tcctgaacca tagtctttat tataaatgga
    28021 ctctaatttt tctcttactc taggaatgtc ctcacgatta tttactttaa atactcctat
    28081 cagcctattt gaacgtaacc tacttacttc atcataattt ttagatattt cctgtaccat
    28141 agacattgga actatttgca ttaatgtata ctttgaacta gtatctacta ttttaggaag
    28201 tgtgcttgta atagctccca ctttcatgtt gtaagtataa tcccctttat cttcgtcata
    28261 tactttttca tttaatttaa tgttatctcc tattgaaaga tttaaataat ctatatatac
    28321 tttatttcta cgtgtactac gattaatatc ttcctcctta ttatatacaa ttgaggttgg
    28381 attttttgta ttataaaata actttgggtc tacagaaatt tgcctacaat attctgtaaa
    28441 actcttatca tcaagcccaa ttatatttga aattatacga aacttgccat cacgttctat
    28501 aggagagtat tttttagatg aaactatact tttaaatcct ccatttttcg caagttcttt
    28561 tgatgcatct ttttcagtca gccaagtgga agcagacatt ttttgataat atagtgaact
    28621 ttttacacct tctgtattat ctaatttttc aatgaaagca gactctatag gttcactatt
    28681 ttccaaataa actgctatat ctctttggtc cttataatta tcacttccat aaacagcttt
    28741 tgctccttct tgatttgcaa ttatatgcaa aaaacatgta agtaataaaa aagataatgt
    28801 taaagatatt gttgcagtac gataagattt tttacgagca cgtagtgcgt ttgatgcaag
    28861 ttctccttct attccaaata tctttcctaa tgaatattta tgcgactttt tgattttaac
    28921 actatctcct tgtcgtattg cttctatagg agatatcttt gatacttttc gtgctggtat
    28981 aagtgcagaa atccagactg ttactattgt aagtaaaact gctggcagaa aagcaggaat
    29041 accataagta aataccactt ctggaacatc agtatgataa ttaactgaat taacataaac
    29101 tataagccta ttacacaata accatcctaa aaataaacct attggtaatg gtataattgt
    29161 cagtaaaaag ccttcaaaca ctacagacct tttaatttgt tttggtgatg caccaacact
    29221 agataatatc cctaactgag taagtctagc atttgcagac agtgaaaacg cgttgtaaat
    29281 caccattaca aacacggcta ctgtaaaaat tgctattgta agatacataa taggagttga
    29341 aaattttgat atactactca tagatgcttt ctgttctggt gaaaagacta acatctttaa
    29401 aagataatta ctattgtatt taagattgta ttttccatat tcattagtct tccatcccaa
    29461 tgatttagca agttttggaa gttccttata cgtgtctctt atatttttaa atcgcaagta
    29521 cacagttata ctatcattag gttttatact tgttttatca agatatccaa gagctgtata
    29581 tgcaggtatt actgatgaag tagaaacatc tacctttcct actattgtca atgtagcctc
    29641 tgaaattttt ttaaaacttt cccctttcga ttttggggct atgggttcaa gaggctttcc
    29701 atttaagatt ctatatccta ttgggagagt aattttatca ccaattttta cacttggatt
    29761 attctcaaaa tattgttttg ataatgcaat ttcattagca ttatttggtc gacgaccctc
    29821 tattatagta tccttttctg gcatagaatt ccaatactct gatgtagcat ttctataaat
    29881 tatataatct cttttctcat cattaatttt gcctacatac cattgtcctt ttaccattac
    29941 atcatcaact gaagaaaaat tttcaattaa tggtaagtca cttccataag tatagtcaaa
    30001 caattcacca tgccagttac cttctttctc aattgaaagt cttataaaat ctgtccacat
    30061 ggtatacaac agtccacaca aagaagacat catggttgta gtaagtaata tagctaacat
    30121 tatagctata ctactacgtt tattgcgtcg tacaaagtct aaggtgtatt cttgaagaat
    30181 attcatttct tcaccacctt ttcagagaca atcactccat cttccatagt tacaatacga
    30241 tttgcctcta gtgctatttt ctcatcatga gtaataagaa gtattgtctg attaaatcgt
    30301 ttatttgata agtttaacaa gtctacaatt tcttctgaat tttttctatc aagattacca
    30361 gttggctcat ctgctaataa aatagctggt ctatagatta aacttctagc tatagatacc
    30421 ctttgttgtt gtccacctga aagttgactt ggaagatggt ttaatctatc agataatccc
    30481 aatatagata caatctcaga gaatctatcc tcatccacct ttcttttatc aagtaacatg
    30541 ggtaataata tattttttct aacatcaagg gtaggtataa gattataaaa ttgataaata
    30601 agacctactt ttctacgtct aaaaactgca agagcttctt cctttaaact tgatatttct
    30661 gtatcttcaa cataaatctt tccagatgta ggtctatcta ctcccccaag cagatgtaac
    30721 aatgtagatt tgccagaacc agatgctcct acaatggata caaaatcacc tttttgaact
    30781 gataaattta cattattaag ggctgtcact ctggtttgat ttgaaccata tatttttgtg
    30841 agattttcac attttaatat ttccatatac aatcatctcc tttatggtta aattttagca
    30901 acctaaaatg acattatagt gacatgaata caaatataaa ttactattaa aaatattgtt
    30961 tagtttttgc acattattta aaattataat ataaaacaaa aactatgcaa tatattttat
    31021 ttatactttt aatatattac atagtcttta aaaggtatta actttaaatc tataggtatt
    31081 caatttaata atcaatagca agtattttat gtactaaagg agttttgctc tatatagact
    31141 caatttagta aaattattta ataaatatta cagactatag gtaaataata tttacaaata
    31201 aaattaagtt tattccctta cactataata tttcttaatt atattaattg caatttcctt
    31261 tacctttggc cctgtaattt ctttattgga atcatctgat ttaatagcaa aataataggt
    31321 gtcaccttca cgctctagca taccaacaaa ccatgcatcc acacgtttat ttttttcatc
    31381 aaatcctgtt ccagtttttc catatacatt tatgttttta tcatttatat ctattttcat
    31441 aatatctctt aaaatattaa tatgctcttt tttaaagttt gtatctccct caaatatttt
    31501 tgccattgtt tgcacttgtt cttttggaga tatttgtaat gaagattcta accaaaatcc
    31561 atttaaatgt ccctttccat tttttaaatc gccttcccat tcgctaatat cgcaattccc
    31621 atactttaaa tcatctaaaa tgttttggac agatttagca tcaactttat ctatcaattt
    31681 tttgtaatac caaacacaag actccttaaa tgcctcttct aaactaagat ttttattcca
    31741 atttttattt ggatactctg taccatcata tcccataact gattcttttg agtttattac
    31801 ccctttttct aaaccaatta aagttgaaac tattttaaaa gtagaacatg gtgaccttct
    31861 tgtttcaatt aattctttgt tatatatatt atattcttta tttttagtat tataaaaaat
    31921 agctcctcca ctaatacctt caaaacaatc actatagtca accatattaa ttttttcttt
    31981 tttgttttta tcattgtttt caattttgga tttatttaat tcagacttat ttaattcaga
    32041 ttttatataa ttcttatcag ttttttgatt tatatcgtta tgttttttcc ctacataata
    32101 cattaccata actacaccaa ccaataagat agctatccaa ataaaattct tttttctttt
    32161 cataatttat atcatctccc atatttaaat ttataaccta ctattaaaat agtagacatt
    32221 atttgtaata tactccaatc taggttctac ttataagaaa caagactaaa tgaatagctg
    32281 tatctcttat attttcttca cctagtacaa ttatgttgat taaacctatt gcgaagataa
    32341 ttaggtaact attaataaca tcctgtcctc cttttaattt gtgatataat aattgattcc
    32401 acatttaaaa cttactattg taatatttaa atattacaat agtaagtttt aaatgtcaag
    32461 ttagtttagg aaagttattt taattgtata attgttatta catttataaa atatggcatg
    32521 tttaaaatta ttttgctatt gggaggatta agataagcag tattataaaa gctataaatt
    32581 ataaaattta atatataatt tatagctttt acttttacaa atattgtttt tattgattta
    32641 ttaatgaatt ttattgacag gttatattta tataagtaaa cacttacata ataagtatat
    32701 aatctacata tctataagtt gagtcaattc acaagtatat gtcaacttaa gtttatgcat
    32761 agctcgtgta caggcaatat ataacaaact gcggtcataa tcactataat atgttttatt
    32821 atttactgaa ggtacaataa cttcatcaaa ctctaaacct tttgacattt taatagaagt
    32881 tatggatact ccttttgtaa agctagaact ttcagaagat attaagtgaa cactatattc
    32941 ttctcttaac gcatcatata cagctttagc gtcattatct gtctttaata taataccaag
    33001 agtcgcatta tcactctttt taaattcttc aatttctatt tttatcttat ttatttcatc
    33061 ttgctcgtta ttacatttta ataaagctgg ttcttcacca tgtcgttcaa taggctctaa
    33121 tgaagatatg tcttgaatct ttttggcgaa attaataatc tcaaaagtag aacggtaact
    33181 cttgttcaac ataactaatt ccccatcatt atatagctgt ttcatatcat ctagtgtatg
    33241 agtatgatta ggattaacca attgtccaaa atctccaaga atagtctttt tacacttaaa
    33301 aagtaagttt attacagcat attgaatagg tgtatagtcc tgcatttcat caataacaat
    33361 atgccttata atcttatctt cttgtatacc ttcatatgca gcatgaatat atataaatgg
    33421 gtatacatct gaccattcaa gtgttttctt ttctgccatc acaaacatgt ttgatatatt
    33481 catttgttta aagaaatcct tatatagtgt aagagtattt tttattgtca acattccatt
    33541 caaactttta agtatacttt ttacctttgg taaatcttct tccataatat tatctgattc
    33601 aaatttataa tgaatgtctt cagctacctt ctctaatctc ttcttaactg gatatctgtt
    33661 atatgcctca aatctactct gtatccagtc acttttagct gtaaaacttc caaaagtgta
    33721 gtcttttgga ataaaaatct tatttggcat ttgttttata taatcatcaa taagttttac
    33781 aaaatcaagt gtagatttaa aacgcactct ttcagaccat ttagcatcat ttatttctaa
    33841 tgggtctttc tcactttcaa aattaataac tctatctaat tgtacctctg ctatattttc
    33901 aaaacttaat tcacataatg gctcttctcc aagctcagga aggacattgg aaatatagtc
    33961 tccaaagact ttattaggtg ataggataat tacattattt gctgatattt tatctttaaa
    34021 tcgataaaga agaaaagcaa ttctgtgtaa tgctatagat gttttcccag aaccagctac
    34081 cccttgaata atcagtgtat cagctttatc atttctaata atttgatttt gttccttttg
    34141 tattgttgaa atgattgact tcattttttc atctgaagtg tgactaagtt ctttttgaag
    34201 aatatcatct tgtatattaa tggaactttc tagtgcatat tctaattttc catttttaat
    34261 tttaaattgt cgttttcttg ttatttctcc atccacccat cctattggag catcatatcc
    34321 agcttttccg atttcataat cataaaacat actggcaatt ggagaacgcc agtcaagtat
    34381 tataagctca tcttcataat caaatgcaaa tctaccaata taatacttag attcatcatc
    34441 catatctttc aacctaaaat ctattctagc aaagtatgga gaatctttga ttttattaat
    34501 cttatctcga acttttacca taaaagcccc atagttatct atttgtttta gtccttgttc
    34561 attttgaaac atttcatgtg ggtctatttc accacgattt tttaccatat acattttagc
    34621 atccatataa tccttatcaa gcttgtcaac aagattttca gctttcttaa aagcattgtc
    34681 tagcttgtta tttatctcta ttagatgtgc aatctcatct ggaaaaaaag ttaataactc
    34741 tgcatcatat tcacacatat tatgtttaga attagatgca ataatatcgc aatttactac
    34801 ttgtttattt tcagacattt aaatcctcct ttgttaatta agtacttaca ctgaatcatt
    34861 atacttaatt gtgttttgga gtttttaatc attcttgcta tttaacttaa aggaagaata
    34921 aatttttgag taggatatcc aaattccaca agcaattctg cttctgcaaa gcccaacttc
    34981 tttatcatat ctctatgtcc tgtatcagct ttgtcaccct ctcgaaaggt agtaattgaa
    35041 atatctgtat ctatcaagaa atcttcaata actttcttca aaaacacttg tgcaatgtct
    35101 gaattacgat actgtggatg tattccaaaa aaatcaatac ttctagtttc tctattaaac
    35161 accatatttg caatagcgac attattaagt tttaatatta aagctctttc ttctaaaata
    35221 tactgttcta attgatatat atattcttcc tcttgcaaat tgggaaatcc atctatgact
    35281 aatctcacta aattcatcca taatggtatg tcagacatac ttgcaagttt aatttctttt
    35341 tccaactcta gtacattctt tgaaaatagg ttatcttttt tcaaaacaaa tcttagctgc
    35401 aaaggataaa attcttgttc tttcctatat ttatttggag attttttata catagcttta
    35461 aatatagaag tgaatgcctg ttgactttca tatccagcta tcaatgcaat ttcaataatt
    35521 ggtttctttg aaaataccaa taattttgct gcttctgtca actttctccg ctttatgtaa
    35581 tcatgcattg ttaggccaac agaagttgtg aaagttctat gcaggtgata ttttgagtaa
    35641 tgaacagcat tagcaactat atctaaatcc agcttttctg ataaatgctc ctctatatag
    35701 tcaatagcag ttatgacatt aattactttg taagacattg cagcttccct ccttttatcc
    35761 atgcaacatt atatcaatta ttacttagtt atatttaatg aatcttgcta ttttataaac
    35821 aaatttgttg tttaagtttt caattcataa atttaatata ttacttttta ctttctgatt
    35881 aaagactcta atcctttaat tttcaataac ttttcattta gtaaatctaa aaagttattt
    35941 attattttct tcttattaga ttccttaatt aaatgataaa tatttatatt atacgactaa
    36001 aaacagcttt ttacaattat ttaatatgat tacaaactta ccctatctta aagtttaatg
    36061 gggtcctgtt atgaatcttt ttattttaat ttaagctctt catcagttta ttttatatat
    36121 tgatgtattt gatttcatac aaaaaagagt gcttcatgaa ctaaaaagtt catttttaaa
    36181 cactctcttt tatgtaaata aatttctatt ctattttgaa atattataat ttgacttata
    36241 atctattaat accaaaaata ataaattgta cgtctaagaa tagattctaa ttagttgctc
    36301 agtagtaaaa tctgttttta actaatcctg ctttgtatgt tgaacatatt ctataattgt
    36361 accatctgga tgtctcaatg tcatattata tcctgtagga acttttttct tatctcttac
    36421 tacaactgct ccattatcca atagataact tctccattca tcaacagaat caaccataaa
    36481 agtagatttt gtttctataa atggtttaag agcatcatca gaaccagata atagtaaaac
    36541 atttcctatt tgcgctaatt ccaacccaac ttctttatag gaaaaacgca aagaacattt
    36601 ttcttttaaa agattctcat aaaaaggtat ggctttttct atatcttgaa tataaaaacg
    36661 tgttaatata tcatatattt tcatattttc cccctatata tctatataat attacctcta
    36721 aattatacca ctctacaaat tatataacaa taaattaagc atagcctttt gagcatctta
    36781 agtagacctt aacaatatat tggggttaca ttagaataca taaattaaat caccttgata
    36841 ttatttagga taaaatttat gtagtagcag taaatgttct tctaattatc aactaacaaa
    36901 cgataatctt taactttcta tataatgggt aacatcattt tcgtaagata ttcactagct
    36961 ggacgattga tatcatttaa atactggtaa tatatatcgc catgaagttt atatccattg
    37021 ctatttgccc atgaaaataa gtcttctaaa gtagggtctt gtaattcata aagtcctaaa
    37081 tcaattgcag ttattatttt ctgtgcagga acaatctttt gtagaatctc atttttccca
    37141 tctatataag tggctacagg aaaccctact tcaacatcca attttactaa atccatgtta
    37201 tgaaaacata caatcggtgc tcctgaagat aaaattcctc tctcctccag atatttagaa
    37261 attttttcaa aactttgttt tgaaaactct gaaaattcta ccataaagtc aattgttttt
    37321 cgtattgcca aaaaacagta ctcagattgt tcagctattg ttatattgga tattctagtc
    37381 attttattcc tccattactt tattttcatt tctaatcttt ttataccaaa ttatacgaaa
    37441 attcactgtg taactaatta tttcatatga atataaaaca taacctcctt ccatttctta
    37501 tatcgaaagt atagcaaaaa taatctcatc attcttgtca cacagtgctc ttataatcag
    37561 aacatactta aaagacttgc ctaattttta ggcaagtcta aaagaaatct ttttctataa
    37621 aaaatttata caaacaatta aaatatcaaa atatagacta atataaaact ataaatttac
    37681 taatctgaac ctcccatggc taaagtcaca agattactga tttatagaat ttcgcacact
    37741 aaaatatgtc ttactaattc cccacaggct acccccctag ttcctacgtt cttacataag
    37801 ttatctatta tcaaacatca aaatttaaac aagtttcagg ttcatcttct attcttgcta
    37861 ttttaaactt acatgcaatt aatactaaag atactattgg atttataata tttaataaag
    37921 cgtatggacc atatgttagt gcagatacac ctaatgttgc tgttatatac gccccgcatg
    37981 tattccatgg tactaatgga gaagttaaag ttccactatc ttctaaagct ctcgacaaca
    38041 tcttaggatg tatacctctc tttttatatt ccttattata cattcttcct ggtataacta
    38101 tagatagata ttgttcacct gctattatat tggtaattgt acaagttacc atagtacata
    38161 atactgttcc aaatacaccc tttgctaatc ttagtaaaga agatgctact acttcaagca
    38221 tacctgtttt ttctaaaata cctccaagag ataaagcgca tattgttaag gatacagtgg
    38281 acatcatatt cataatccca cctttagata ataaagcatc tacctcctgt atttgtgttg
    38341 acgaaacata tccattttgt gctgcatcta atatcgtatt catagattct ccttgaaaaa
    38401 ctactgcaaa caatactccc aatacagcac ctactataag ccctggtata gcaggaactt
    38461 taaatacaac caatccaatt actattgctg gagctaataa taatactggt gataaagtat
    38521 taaatgtaga atctaatgta gacctaatta attctatttg ttttatatct agtgcttgac
    38581 ctgaatactt cattccaatt acaccataaa ttactaaaca aattaataat gatggtatag
    38641 tcgaatatag catatatttt atatgtgtaa acaaatctgt tcctgccatt gctggagcta
    38701 agttagtcgt ttcagataaa ggtgatagtt tatctccaaa gtaagctcca gatattatag
    38761 aacctacgat taatccaatt ggcataccta aactttgacc aattcctaaa agagctactc
    38821 ctactgtacc cattgtgctc caagatgaac ctgtcgcaag agatactatt gcacagacta
    38881 atgttgatgc tactaaaaaa atatttggtg ataaaatttt tagtccccag taaatcatac
    38941 atggaactac tccacttact atccaagttc ctataagtac gcctattata attatgatta
    39001 agattgcttg cattgccatc tttatactat taaacatact taattctaac tctttccatt
    39061 taaatccaag tctatataca gccacaagtc ctgctactgc tgctgctcct attagtggta
    39121 catgaggtga tgaaccatac actaatactc ctagacttaa aaataatatc aaacaagtaa
    39181 ttggtatcat tgcatcaaac agacttgctt ttctacattc tcgctctttc ataaaatagt
    39241 ttcctcctaa ttatttaaac actacactat aatttttttt gaaacatatt tgctcgtact
    39301 agatgacatg atacccccat aagttaataa aaattctaaa ttgtcaccta atttataatc
    39361 atattttgtg ttacttacat ctagtatcat gtggtctgaa cttgccccta atatttttat
    39421 atcagtgtct attggaatta aagagtcaat atttatatct tgtttaccta tagctatgat
    39481 tgcccttttt aagattccct tatcttcata aacaggttta tttctaaagg catcaactcc
    39541 tatttctcca ataggaactg atggtttttc tttacattca actacttggc atattaattt
    39601 aaatgcatct tgatatgttc catttatatt ttcaccgtat gccgtttctc taccaagtag
    39661 aatggactcg cctattctca aattagtaat accttctggc atattattat ttatcaacag
    39721 atgaatagaa cttgaattac ctccagatac tatttctaga tttattccaa atttttcttc
    39781 cattcttttt gctatactta ccagtctgcc tatattttcc ctagatggta taatagctcc
    39841 ataacaggtt aagtttgtag ctataccaat tatttcaata ttttttaatc ttactatctc
    39901 tcttacatta ttaaaaaagt cttcttcata aaagtatcct tctcgtaaat cgcctaagtc
    39961 aaacataaga actatcttat gaataatatt tttactttca cataattcat ttaatttctt
    40021 tattgttcct aattctgagt taaaactaat atcgcaataa ttgataactt cttctaattc
    40081 acttaacatt gggattctaa tcaatatctt aggtagattt atatcttgta aattttttaa
    40141 gttttgtatt cttgaatctg ctatatggtc tattccttca ctacatattt cttctactat
    40201 ttctttttgt gcacaaaatg atttagtaac aaaagatatc ttaatatttc tttcatgaca
    40261 catctgcgaa attaattttg cattatgctt taacttttct atatctattt ctaacctagg
    40321 atacataatc tttcctcctc aaaattcaaa ctttttaaca ggagcttaag agatgcttct
    40381 tcatattttt tagataaaac acccatagat gccataatat agtcattatc tattaatatc
    40441 tttgtttttt cctttggaaa tagtaattca ttatttttat tgtatttgag catattatct
    40501 aatatttcaa ttctactagg gagcctagta agtgctcccc ctgtaccaac tatatatctt
    40561 acttctgtta aatctttccc ttctgcaatt ttgacttttc cagttgttcc atagatattt
    40621 cttatttttc ctgaatgtct tagcatagct ttaacaacag cttcttttgt caatctttca
    40681 acaaataata tttcttcttt tgattttggt attggaggat aattctctat tactgcatca
    40741 atatctatag atagttcact ttgtaagttt tctttaccta taacttctac tatattcttc
    40801 atatttacat atacacctaa atccccctca acacttctct ttgcagtagg ttcaggatta
    40861 accaaaattt tattaatata gtcacttcca tctgtaacag aatgtacatc agtagttgct
    40921 ccacctacat ccagagttaa taaatctcca atatttttat ataaaagttt agaagcttcc
    40981 attacagctc ctggggttgg agtaatattt tcattaacca tttctttaat gtatttcatt
    41041 cctggtgctg tagttatgtg ttcttcaaat acactttgaa tgattcttct tgtaggttct
    41101 atattcaata aatctatttt agggtataca ttttcagtta tataaagctt ataattagta
    41161 tcttcaaata ttaaccttat ttcctcttga ttttcaacat taccagcata tataactggt
    41221 atgcctagat tcatagaagc tatcatttct gcattataaa tagctgtatc tctttctcca
    41281 taatcgactc caccagctat taaaattatg tttgggttta tttcttttat tttatttaaa
    41341 tcagttcttt taattctacc tgatgttatt tgacgaataa cagctccagc ccctaaagct
    41401 gcttctttag ctgcttttac tgtcatatca tagactaatc catgaacagt catttttaat
    41461 ccaccagctg cactagaagt tgcaaacata tcattatact ctatatcatc tacagataat
    41521 ttattagcta aatctttaat agcacctgat aagccatttc ttacatcgcc accttcaaac
    41581 actgttgttg gagcttgacc ttgacccaaa aatataggat tgttagtatt aatatcgtgg
    41641 aaagcgttta ccactgtagt agtacttcca atttcagcta ccaacacatc tatttttaaa
    41701 gaaaccttgc tattttccat tatttattac tcatttctct tcttttttca actaagaaag
    41761 tggctacatg tatgccttta ctgtttcttc caaatccagc atctatgcct tgttcaacag
    41821 ctatttcagg tgttacttgt gttcctccac acgcaatcat tactttatct cttatacctt
    41881 tttctacaca ataatcgtgt aattttttca tgtttttata gtgaatatca tcatgactta
    41941 ttattgtaga tgcaagtatt gcatctgcat tcagttcaat cgctgcatct accaattttt
    42001 ctacaggtac agaagtccct agatagtggc attctatgcc atatttttca atacctccat
    42061 gttttatatc tattatttct cttaaaccaa ctgaatgttc atcttctcca accgtagctg
    42121 aaactatttt cataggtttt tcttctatat ctgctcttat ttcttcatca gttagtacct
    42181 taggttcttc tggtattact aaattgttta aatctatatc aaacggaact cttcctttca
    42241 cttctattct agtcccttca gattcatgca taacttctct acttatgacc tcaatttctt
    42301 gtaagttcat ttttttgaca aattccaaag ctgcaaactc tgctgttctt ttatcagtag
    42361 gaagcatcat tgttatcatt ataattccat ctgcacacca ttccatttca ggcttaattt
    42421 tagttccatt tctgtactca tatgattctt ttagtctatt ttctacatta tcaaaatcgt
    42481 caagctcatc aatatatatt attttgtctg gattttcaaa tgtacatcca tctattaaca
    42541 ttgatggatt atctatagca ttttcatcat attgagctac attattgtat ccaaagtgag
    42601 cagttacagg tgctaaataa tcttcttctc tttcataaac agtaccttca ccaactccac
    42661 cttttatttt tctagatatt ccatcaccat ttctttctgg ataatttcca gaatcaacaa
    42721 aaaatccttg ttccacagat tcaaaatatc caccaacttc agatatttct tccatatata
    42781 atacagctct ttctttaagt tctcttgctt tgtctcttaa ttcaccgaca tctttaagtt
    42841 ctatcatatc cataagccca tccataccaa ctaaagcttg ctttgctgta tcacatgctt
    42901 ctatattgta tatatgccaa ggtacatttc taccttcatc aggtgttata gttgattgta
    42961 tgtcagctct agttaatact gatgttaata agtttaatac atgagtaact gttgcttctc
    43021 tagttgatga ttccatatat ttagtattca tttgagctct catcttataa tcactaaata
    43081 actctctaag tgcaacagcg taaggtaagt ctatttttaa acatggtgct ggaggtgctg
    43141 ttggtggaac tgttgataag catatattac ttttatctat acctattttt tctgagaata
    43201 tagagtttaa agcgtgttga accataagtt caggcattac cttccatgct tctctagcag
    43261 tagcattagc attatgtgct ccatcaattt gagctatatt ggcaaaagcc attattttct
    43321 ttgcctcaca agcatctaca aaagacctta ccatgtttat attcctatac agaacattat
    43381 attgtgggtc ttgatgtgct ccattaactc cttcctcagc aaacattact gctacttcag
    43441 gaccagcaac accacttaca tatgaatgat aattaatagg tctaccaact tcttcttcta
    43501 taaaatcaag agccttcctt tgagctctta cttgttttct tgttattgga actccaccta
    43561 taccttgtgg ggttccttct ataagcccat caaaatgtga ttgtccagca gttctgataa
    43621 ccattagatg gtcagctcca tgatgagctg ccattctcat tcttcttata tcatcctcaa
    43681 atctaccaga agctatttca gtagtaataa ctggacttgg ttgagggtct atattattga
    43741 aatacttaga tgatggtagc cctacactct tctttaaagg ttttgtacag tctttatatt
    43801 taaaaggtcc catttcaaga ttttccaagt gttctctcca aacccaacct cttcgttttg
    43861 gtttatattt atccaaatct tttaatatat agtctatatc caatttttta ttttccttta
    43921 acatgattct accccttctc taaataaaca tgtaacttca tcccaatatt cacccttaac
    43981 taataacaaa cctgcttctc taaccgttat atttttagat ttagccaatt tataaactac
    44041 atgccctgct cctttaccta taagacctct ttccataacc ccttctaaaa taggttttac
    44101 ttcaagagaa gaaaatccca ttctcaacaa gacagacctt tctattgatg gtgttgtatt
    44161 ctttttacca agttctatca ttggttctac tatctgggta gctaaactcc aaaacctttc
    44221 ttttaactca tcatcactca gttcttgaag atgttttctt ctaacttcaa aatcatcctc
    44281 tctttttttc atgaacattc ctccattcgt attgatttaa tcgaattttc tgaattttta
    44341 ttttatatta aattaaaaaa caataattac tataaattat ttaatacatc aacaacaaaa
    44401 tctcttgaac tttttacttc ttccattaaa aattctatat ctcgattact tagcttatca
    44461 atattatcaa tgtgattatt agatatacaa ttttttataa atgactttct tattttattc
    44521 atatcaatat caacacattt caataattct ggtctttctg gtaatattaa gtttactcct
    44581 gcaatttctt ctcttggatt tccaaatttt atatctattc cattttctct tgcaaaggta
    44641 agttgtggac atatatgttt acctgcaccc gtatattctg tttcttgtac cactatagct
    44701 ttatcctcat ctagctcttg agctaaagag aatgctgctg ctaaagatgt atttcctgct
    44761 ggacctcttt ctataccttc tagctgtgcc aataattcag ttgtataaaa aacttctcct
    44821 tgttttacta atacatatct atccatatat ctaagtggtc tagctgcaga cctaggtaca
    44881 tctgacctat caggccatgt acagtatggt atcccaaaac ctgtatgtcc tgttgtaaat
    44941 gattttttat taaattgatt atcactagcc atgtgtaatc cttttaaatc tacacttgct
    45001 cctactactt tagtattaat agaaccagct tttatcaatc ctcttgcagt tccagtaaga
    45061 ttaccaccac ctgcatttgt acaaacaact atatcagggt cttttttata cttttctcta
    45121 aattggatag ctaactcata acctaaagtt tctacacctg caattccaaa tggtgaatat
    45181 aatgatgcgt taaaatagcc tgtttcttct aataaaacta agaacgtata aaataactct
    45241 ggtccaacag ttaactgaac aacttctgct ccatatgcct cacattttcg cgctttttct
    45301 atgatttcag gttgacctac accattagaa tcataacatt cttgaactat tatacatttt
    45361 aatccctgca ttgccgcttg tgatgctaca gctgcaccat agttaccact ggtagctgct
    45421 attacacctt tatatcccat ttgtttggca tgatatactg cagtagctgc tcttcttgct
    45481 ttaaaactac cagatgcatt cattgcttca tcttttacaa atattctagc tcctttacct
    45541 tctttagcac attttctagc taatttagtc aaatttttaa gctctattaa aggagtattt
    45601 ccaacagcat actgtgattg aattgcttca atatcttgta atgtatatcc tgtttcactc
    45661 atcattttct cataatcaaa ccctattccc tcttgttcaa aagaagaata atccaatccg
    45721 attgcatttt tcattatttc gttatttctt cccataacag cttgataact catatctttc
    45781 attgatgttg aattattcat tatatacacc tccaaataat atttctttag cttggattcc
    45841 tatttggagt aactctggta tacatttacc ataatcatga gtataatatg gatttatttt
    45901 aagtaaatta ccttttacaa gtctgcctgt aattgtttta acttctacta agtcgcctat
    45961 agaagcatca ctttgtataa aacctttaac ccacatttct aaggatactt tcttagtatc
    46021 ctctggaact tgtggagctc tttcttctgg agtcaatact atattgtgta taataaccca
    46081 atcattaatt ttagcatcca ttttttcatc cccttattaa ttgactattg ccttactaat
    46141 taatttactg ttattttaaa ttaaacatta ttttaccaat tagctaactg ttatcttact
    46201 aattagctag ttgctatctt actaattagc ctttgattct tcttccaatt caacttctat
    46261 ctgatttctt atatctccca ttattgctct aggtactggt atatccaaca tagttttaag
    46321 acctggtcta gcatttatta ttaatggaat agagtttact atcattgcat aagtacctac
    46381 tcctccaggt atttcaggat ttatttgtaa atcaatgttt ggtatacctt ttattgatac
    46441 atagtctcct gttttaatac cttctgcttc tggtattatc tgttgtggat gctccatttc
    46501 aattaaaact tctccattta catatccata tccacattgt ctacaaccag caacatttcc
    46561 agccaatgcc tctccgtact tagattttct atctactgta gtcattattg gctcttttgt
    46621 ttgttctatc ttatctaatt tccaacctaa tccatcagct atcatattta ttgattctac
    46681 aaaacctaca tgacctgcta tagtcttatc ttctacacct tttataaatt cttcccttgt
    46741 tactccaaca ccttgttcca ccataacaga ctttccaaat ggagataaat catttactct
    46801 cttagctttt atactagtaa cttcttcaca agtacctgaa agtgccaata ctagtaaatc
    46861 taatacaaat cctggattta ttcctgttcc aagtatactt actccatttt cctttgcaac
    46921 ttcatccatt tttttagcta aatctgcatc atcagcttgt ggatatgcca tttgttctgc
    46981 tgttgatata acatttattt ttctatttaa taagaaattt attttatcaa aagccttttt
    47041 agtaaatgaa tcagttgcta acaaaacaac atctacactt ttttctctaa aaacttcttc
    47101 ataattttta ttgataataa cttctggtct ttctcctctt tcaattccta aaacatcata
    47161 catacttttc cctgaagtac ttctactaca aacagatact atttctatac cttctttctt
    47221 tagaatcata ttagccatac ctattcccat agctccaaat ccccatattc ctactcttac
    47281 ttttctcata tatacaccct cctaaaaatt tatatattct caataattag ttaaagcata
    47341 aatcgtgcca actttaaaat taaagtaaat atttattgga acgttgaaac tataattatt
    47401 ttattatgta ttttcataaa taaaaaataa tatttcttat gagaaataaa aaaaagagca
    47461 aaatattttg ctcttttata ataattttgc tcctctattt tgctttttta ttttactttg
    47521 attttgtttt tttatcttgc ttatttataa tattttgata ttatattttt ttattttata
    47581 ctgtaaattt tgcctattca tacctaaaat tgatgcagct ttagttatat tgtaagatgc
    47641 cttttctaat gattcatata tatacttttc ttctatctca ctgataatct tactaagtgt
    47701 tttgtcctcc aaatcgttta aagaataatt gttactctct ttattctctt taagagtgta
    47761 atagtcgttt agattaatca tacttgtttc tatttgtacc tcatcttcca tcatactcat
    47821 agtacaataa attatgtttt ctagctctct tatgttacct tgccaatcgt aattttttaa
    47881 aattttaata gcttcatctg aaattcctac cactttttta tttaactttt tattatactt
    47941 tgaaataaat tttttgcaca atagaggtat gtcctctttt ctatctctaa gaggaggaat
    48001 ttttatatga attatgttaa gcctataata taaatctttt cgcattttat gctcgtttaa
    48061 aattaccttt ggactttcat ttgtcgttgc aataattctt acatctatag gtatatcctt
    48121 agttcctcca acccttctta cataaccttc ttgtaaaacc cttaatagtt tagcctgtaa
    48181 cataataggc atggaattta tctcatccaa taacaatgtc cctttgttag cttgttcaaa
    48241 taagcctggc ctatctattg ctcctgtaaa tcctcccttg ctagttccaa aaagaatacc
    48301 ttcgaatagt gattccggca aagctgcaca attttgtgct ataaatggat agtttctcct
    48361 attacttcca tagtgaatgg actggctaaa taactcttta cccgttccag tttcaccgta
    48421 tataaatact gaagcatcag acttgcaagc tttcttagat ttagctattg cttctttaat
    48481 caaattactt tcccctaaaa tatcatcaaa ttcataaccc tttttttgtc taatactaac
    48541 tttattgact aaattttttt tataatttct atttagtaaa ttttctatcg ttgtcatatt
    48601 ctttgatatt tcaagtgccc ctacaaactc gcctttaata tcaattggta ttgtagtatt
    48661 aattgctgtt atctcttttc catttttatc cagatatttt tgaatattgt ctttgataac
    48721 ttcccttttt tccaaaactt ctaatagtgt actcctgttt attttcattt tgttgactat
    48781 atcaaaaaat gaattggtta aaatatcgtg tctgttcatt ttttccattt tttgtacaga
    48841 attattgtag attatagttt tcccgtcttt attaacaaaa tgtacccctt catcaatatt
    48901 ttccaatatt tcattcatta ttttaaaaaa tatctcttgg ttcaactata tcaccccagt
    48961 acctaaatat ataaaaaccc aaaaaattaa taaaatgttg ctattgtatt tatcttatca
    49021 tatatttatg atatttttta tgtacattat attaatatat ttttaagtat atttaaaatt
    49081 ttatttatat atctttcatt atggttatat acaatatttg aattgtcatt aaatatgcca
    49141 atagttttat atattattga ttttattaaa aaaagagata tacaaactaa taagttgtaa
    49201 tctctcaaat ataaaaaaac aataaattag ctcattggat tttttagtcc ataatataat
    49261 tatagattat tcaccaaaca atctatagaa attgtggtat taatgtttaa ataaccaact
    49321 ttttctaaaa taacctttat aggaatatat gagttcataa gtaaagatag cgaaataaga
    49381 aaccagtttg gtatgtaaaa tctagatttt taattaaatt atcaagatta tatattatag
    49441 tatcaaaaat agaaaattaa aattaaattt tttataataa attgtataca ttataaatta
    49501 tattaaattt ttaatttaag taatagtata tgtaatcttt agtcatcttc ttaccagttt
    49561 tttatccact tttctaatga agttattttt tcatatgtta attcctcttg aaataatgat
    49621 actaaaagac tttttataaa attataactt aaaagtttat gtattttttt gatatgaatt
    49681 tatagtactt atcttcttta attgagattg tgtatattta actaaacatt acaacaataa
    49741 ttctatgaaa tcaaatcaat tatttacata tttttttaga acaataataa gtatatattc
    49801 acaaaatttt gtgttaatat ttttaatttg tgatataata aaagcaagga aacatatttt
    49861 acttaacttt gagtgatgtt tccttcaaca aattattttg aagatttact tttctggaac
    49921 tttatattaa gttcccagcc actcttagtt ggtcgctcag agtggctctt taatttatcg
    49981 taaatgtaac tggctataac accagttata atactcatca ttagattttc catagttttc
    50041 acctcctctc ataagaaagt gaagaaactt ccatggaaac accactcata gctttttcaa
    50101 atatttattc cttgccatat taattatatc ataaatattg gaaacataaa attttaatac
    50161 ttatcgtctt tattattatt ttttataatt aataattttt tttaataata cataatataa
    50221 atttatattt cttcaataaa aaagacaatc ttaattaatt gtctttttta atatatattt
    50281 ggctaataca ttattttaca caaacattac aagggtctat tttaccttgt gacttagctt
    50341 gttttaatgt tactttattt attgttttac ttctttttag tgtagaacaa ttttttgtta
    50401 gatgatatga ttttccatta ggagttacat atactgtact tttatcagtt aatccaggat
    50461 tattagagct aggctcatta cttggtttgt tcgtattatt tgaattagta tcttttacaa
    50521 tgcctgtatt tgaatcccca acattattag ttatatttaa acattgtttt ataacaacat
    50581 catcaatatt tccaatagca gttattttac ttgcattttt taatatactc ttattacttc
    50641 catttccaac taacactata ggtgtttttt gtgcaattgt agaaccaact aaagaataaa
    50701 ctaaatcagt cccacttgct atgtaaaatt cttttgagcc attataaaat ttatttatta
    50761 tttgtttatt tgtatcgtat ctatctactc cacctattct tgttgcttta gtttcattta
    50821 ttaacttatc actaatactg acttttccac caattgcata agtttctaat ccatctgtag
    50881 caaaacttgt agtgtttcca tcagttaata ctattggaga tttatctcta actgctatag
    50941 aagcaacact catagcatct ggttcacctt taaaagcatt agttaatatt acttttttaa
    51001 cagcacttac acttcctatt tcttttgcaa ctttatgact tgtatctatt ctatcagttc
    51061 cacttattct atttatgctt atttttttat cacttaatat tttctgaact gatgctccta
    51121 tcgaattttt tcctccgatt agatatactt cttttacctt ttctaatctt tttaatgttt
    51181 ctgaagggat tgtatctttc ttagttaaca atattggggc atttttagct cctgacaatc
    51241 cacttgctga caatccatca gataatccat tttcagaatt aataagtatt gcaatatcat
    51301 aattttgttt atctgctatt aaacctgctg tttcatactt atttgtacct tttattgaat
    51361 taatagaact aagagcgttt gatgttggac aactagcaat caataatgaa acagacatcc
    51421 ctattgccaa tagtgttttg tttaatttca taatgaaatc ctcctataaa ttttataata
    51481 ttacttaaat attataattc tacataaaag aatattttcc tttatgaaat tagtttatat
    51541 ttcaaaattt tgtcactttt taaatctata tactaaaaaa tagactattt gtaacagtct
    51601 atttcttagt atatcaaata tttatttagg tttacgtttc tttgtactag tttttgtata
    51661 tgatattcca gttccaggta tactcaatgt agctgatttt cttccttttg aattaactga
    51721 cactctagca cctttaacac cagcacttat acctacactc ttcttaccta aatttaattt
    51781 gagtcctcct cctagattta tgcttttcct aaagttaaat cccatagata taaccttccc
    51841 ttctatattt taaatattta tacttaaaat tatatttgtt atacacttgc catcattggt
    51901 atatctagca tctatatctt tttacgtttt ttcttcttat atactactcc agcaactaca
    51961 gctgctgttc cagctccaac cccataagta gcatttctac ttttctcttc ttctcttttt
    52021 tctaaacctt catcatatac accttttaac ttagtttcaa tagacttcat ttcatctggt
    52081 atactaaaat cttcttcatt gtaaccttga ttatatacac tttcttttgc tttaggtaac
    52141 ttaaccttac cattatcata tccttcttta aaccaattag catatttaac attacctata
    52201 gttgatgtgt caaatctttc tcctttgata gcactctcaa atccttgagt agtgtaatca
    52261 ttttttaatt gttcttgtat ttcgtcataa gcattattat aagcatctat aaatttagaa
    52321 tctatgtttt cttcaaatgt cattttttct ttatctttat tgctatcctc tatcccttta
    52381 gctttatatt cttctatctt tttagtctta tattcattgt atccagttga atatccggta
    52441 tcataagcat tttttaaaac ttctttttca tatgtattat tagatttagc acctgtaagc
    52501 cctagattat atccagtctc tttagcctcc ttttcttcct cttctaattt agccttacct
    52561 ttttcatatc cttctgagta ctttgattca tatgtatcac tataatctcc actataattt
    52621 gatgaactat aatttccttt atacccatct tcataccctt gattatatcc tttttctcca
    52681 acagacctct tttgcttttc ttcattatta accgaagttg ctgttccaga actgcttcct
    52741 cctccagtat aaggacaacc accattatta tgtaaatgag ctggataacc accacaatga
    52801 tagtgataac ttcctaatcc agatttattt ttattatcac gatgacctcc tgatgaatca
    52861 gttcttcctg aatgagcata cgaaaagctc cctacactaa tcatagttat actcattgca
    52921 acagctatta actttttctt aaacataatc tatttccccc taaaatattc tatgatttta
    52981 ttatatcagt caatatatta tgtttaaacc gttaaaattc gacaatgtaa atatttgatg
    53041 aattgtattt gtaaataaat cttttagcat atcttgaata tctgtagttg ttttgacatc
    53101 atattcttca ataagttttt taatatttcg tttttgttaa acataaaaag cgtgcacttt
    53161 tctttgtata gtgatatttg atattttaat tatcactact ttagaagaat acacacttta
    53221 ttttaaaaac cctgatacta tgttattaga aaatggtact aatataaaag atatccagca
    53281 tatactcgga catgctaaaa cttcaacaac tatggataca tatttacatg taactaacaa
    53341 catgagaaac cagacggtaa atatttttga aatcattgta gaataaattt gccacccaaa
    53401 aataattatg gtggcaaata ggtggcaaat ctacttttaa gacacactat aaaagtctga
    53461 aaccctgtta ttctctaata agtttaacta cagtctcaca atgtggcgta tttgggaaca
    53521 tatccataca cttaaccatc ttaatctcat aaccataccc cttaaaatca accaaatcaa
    53581 caaccaaaga cttaggatta caagaaatat aaacaatctc cttagcacca aatccacaaa
    53641 tatccctaat agcatcctta tgaatgcctg gtctaggagg gtcaacaata atcaaatcag
    53701 gcttgtcctt taaatcctta acaaccttag ccacatcccc agcaataaac tcacaattag
    53761 taagtccatt caacttagca ttctcattag cagcaacaac agcttcctca actatctcaa
    53821 taccatacac tttcttagca gcaccagcca taacctgtcc aatagaccca gtaccactat
    53881 acaagtcaaa tacaacttta tcattgtaat ctccaataaa atccctagca atactataaa
    53941 gaacctcagc tcccttagta ttggtttgga aaaacgaaaa tggtgaaatc ttaaacttaa
    54001 gacctaaaat ttcttcttgt atataatctc ttccatacaa tactcttaac tcatcacatt
    54061 ggactgcatc tgctaaacca tcattaatag tatgaagtac acctactaac tcagctttta
    54121 aatcaatccc taaaagcata tctttaaact catacatatc aaaatcttct tgagaagaag
    54181 ttactatatt aactataatc tcattagtgt gaatcccttt tctaactaca agatgtctca
    54241 aatatccttt gtgattcatt gttctataat aaggaagctt tttttcattg aaaaactcta
    54301 cactagaaac taatatcttt gagaagtctt catcaaccaa catacactcc tcaacagttt
    54361 gtatatctat atgctttcct tttttatgaa gacctaatgt caaaggtcca ttttttactt
    54421 catctccaaa agtatattcc atcttatttc tataatattt gttttctgga cttccttcta
    54481 tccctaaaaa ctgaaatcca aataaatctt gctttaaaaa taaatccata acttgttttt
    54541 cttttatttc taattgtttt tcatatggca cagacaatag tgtacatcct ccacactctc
    54601 taaagtgctt gcaagtttct tcagtttcaa gtggtgagtt ctctaataat tctatcatct
    54661 taacttcagc tttcttactt ctaacttttt taactccagc tctcaccttt tgaccactta
    54721 ttccaccctt catatggata actctatctc caacttggct taaagatgta ccaccaaatt
    54781 ccattttatc tacttcaaat tctataacat cttttttctt cacagacatt cctccaattt
    54841 actatagtat ctttattatc tttcttcaat caattttact tcttcatctg ttaactctct
    54901 atactcacct aactctaaac tttcatccaa ttttaaattg cccatagaca atctttttaa
    54961 gtatactact tttttgccta cgctttcaaa cattcttttt acttggtgaa acttaccttc
    55021 atgtattgta agctctattt ctgattcatc atcacttttt aatatattta actgtgatgg
    55081 catagtttta tatccgtcat caagcactac accttctaaa aaagcttcta catcttcttc
    55141 agtaactact ccatcaattt ttgcataata agtcttaggc acatgcttct taggagataa
    55201 aactctatga gaaagctttc catcattagt taaaactaat aatccctctg tgtctttatc
    55261 taaccttcca acaggaaatg gttcaaaagc taagtatgat aaatcaatta aatctaatac
    55321 tgttgggtca tatttatctg tagttgctga tatatatcca tcaggtttat tcatcatcaa
    55381 atatatatat tctctatata taacttcttc tccattaaat aatatctcat cattttcagt
    55441 gtctacttga gttcctggat ttgaaacttc acttccattt actactacag acccttgttt
    55501 acaatacttc tttatttcac ttctgcttcc ataacctaaa tttgaaagaa ttttatctat
    55561 acgttgcttt ttagccatta aaaatgctct ccattctcat aatatttttc tttttcaaat
    55621 actgtaaatg ctaaatccat actttctaca tctaaattat ttcttatact atcagttatt
    55681 attcttgcta ctatatcttg tacttcttgt cctctatcaa accaagctac ttcaacaaaa
    55741 ggatatacat ctgctatttt accatctctt attgcaactg actttataca ttctatttca
    55801 aagtagtctc ttggacattt tacagcttca actaaatcat ttatcatttt ttcacttatt
    55861 ttacatatat cattttcatt aattcctctt atttttatct gtggcatagt ttatctcctt
    55921 tattttaaat ttttagtgaa ttatcatcca cttaattccc ttcgataacg tttgaagtgg
    55981 taacttcttg gtcaagacaa ctattgttat cagtatctcc aaactaataa ggtagttcct
    56041 acccttatag ttagcattat atagctaatt ttcctaaatt gtttatattc tttattattt
    56101 tatttaatcc tattgtcttc tatttaacat tatacttgta atttatagtt attacaattt
    56161 actatatact ttttttgatt taacgttata atataagtga tgggtaaatt ttaaaagtta
    56221 ataggaggag tttaaaatgg cattaattac tacaaaagaa atgtttaaaa aagcttacga
    56281 aggtggattt gctataggtg catttaacat aagtgactta gaacaattac aaggtgtttt
    56341 aaaagctgct aaagctaaaa attcttatgt tatgatacaa gcttctatgt cagctgttaa
    56401 atatgctgga cctcatacat tagttgaaat ggttaaggct gcttctgatg aaataggtgt
    56461 agatgtagct cttcacttag accatggtcc aaatatggat gctattaaaa cttgtattga
    56521 tgctggtttc tcttcagtta tgatagatgg ttctcatttt gactttgaag aaaatgttag
    56581 aataactaaa gaagctgttg aatatgcaca ctctaaaggt gttgttgttg aagcagaact
    56641 tggtgttcta gctggaacag aagatgatgt tacttctgat gttcacaagt atactcaacc
    56701 agctgaggca gttgagttcg ttgaaagaac aggtgttgat tcattagcaa tagctattgg
    56761 aacttctcat ggtgctttca aattcaaagg agaagctaaa ttaagattcg atatactaga
    56821 agaaatccaa agcaaattac caggtttccc aatagttctt catggtgcat ctgctgttga
    56881 ccaaaacgct gttgctacat gtaatgaatt tggtggaaat atagctggtg ctaaaggtgt
    56941 acctgtagat atgttaagaa aagcatcttc tatggctgtt tgtaaaataa acatggatac
    57001 tgacttaaga ctagctatga ctgctgctat cagaaaattc ttagctgaaa atccaaaaga
    57061 atttgaccca agaaaataca ttggtgctgg tagagatgct atacaagctg tagttgaaag
    57121 caagatagat gatgttttag gttctgctaa ctctataaac taatataact tttaaatatt
    57181 tataaaagaa aagagatgac ttaaagtaat taaatttatt tttaagccat ctcttttaag
    57241 ttgtataaat tatgtatctt ataatatttt aattatattg tctttttaaa ctgacagcta
    57301 aacgtgaata tgtccactct ttatctttct atggatggta gaaggatata tacctataac
    57361 ttcagcagcc tttgttattg aaccatactt atttatagcc ttacttatca ttatttggtc
    57421 cactatttta tatgcatcat taagattcat aattccattt accactattg gtgataaatc
    57481 atctgtttca ttatcaatca tatctaaatt tatcagcatg ttaaattcat cttctccaat
    57541 tacattttta gctgataata ctacaaatct ttcaatgatg ttttttaatt ctcttatgtt
    57601 tcctggccaa gaatattctt ctaataactc aataacttta ggcgaaactt ctacttctct
    57661 attgtacttt tcattgtaaa gttttaagaa ataatttact aatggtacta tatcctcttt
    57721 tctttctcta agaggaggta tttttactgg aataacactt aatctatagt acaaatcttg
    57781 tctaaattta aggttatttc taaggtcttc atgagaaata ttagtagcac ttatatatct
    57841 aacatctatt tttataggct tactaccacc tattctagta atagtatttt cttgtataac
    57901 cctaagtaat tttttttgca tctgcattgg taactcacct atctcatcca agaaaatagt
    57961 tccaccattc gcctcttcaa aaagtccctt tttacctttt ttcttagctc cagtaaaaga
    58021 accttcttca tatccaaaaa actctgactc taataattca tttggtatag ctccacagtt
    58081 tatagctata aagggtttgt ctctccttga actatactta tatattgttc ttgctattat
    58141 ttcttttcct acacctgatt ctccatttat aaatatagaa gaatctgagg ctgcagctct
    58201 cttaacaact ttttttatat tgtccataat cttactttga cttatatact ctgtgtcttc
    58261 tgatatatca ctatatttta tctgagattc aagcttaata acccttgaaa tatctctccc
    58321 tgttagtact cctcctgtaa gctttccctt agaatcccat cttggaactg ccgtatatgc
    58381 aataagcttc ccatctgggt aaacgatatt tctataaatc tttttcttca ctttaagcat
    58441 gtttaatatt attggttctt caactaatcc ttgtctcaca aggtctgtta tatttctacc
    58501 aagtacctca gttcttttaa aaggtaatat ctcatcactg acagtgttca tcttttcaat
    58561 taccccatct ttgttaaaca caacaacaac ttcatctata tgctctatta tatcttcaat
    58621 tactttatca gatattagag acttctcaaa taaataaact atattatttt cattattatt
    58681 atctttcata ttgtatatat gtgcagtcat ccttaactct ctgaaagcta ttttcttttt
    58741 actatctgtc agtatttctg ttttgtcaaa atttgaatct aattcattta tatttctagg
    58801 cttttttata tctagaaaac taaaaatact atctattaga tgattacagt atattatttc
    58861 gcctgattct ttacataaaa tggctggatt ttctacatgt tctataagcc ctattaaatt
    58921 attatccatt aatattcgca cctttcatta agtaatttat tgaactacat acaaaattta
    58981 ttgtttgctt acaataaata ccatcagcac atataatcaa ctccttataa tattcgtctt
    59041 ttcaagtagt ttatttcatt aaaacgtaac taagatataa ttttaatgat tatagtttgt
    59101 taaaaatttc attttgcttt taattgtatt ttatcacata tttagtaatt atttgtctat
    59161 ttaatacaat ttaattaaat ttaagattta tttaaaaaaa caaagataat ccttacagaa
    59221 tataactcac aatttgtaag caatatacat ataaggatta tccagattat cttgtattat
    59281 aaaattttat tcaaacagac tttttaataa ctgacaaata cacactagca ataacttatc
    59341 aaagggttaa taattatgtt actaactaat aagacttatt caatcagtaa tatttatata
    59401 gtttgtatct attaagcttt tatagcttct aataaatcat caacgctatc taatttttct
    59461 ataagcattg gaactatttc atgtaagtct ccaactactc catagtcagc gatttctaaa
    59521 attggagctg ctgggttttt gtttatagca attatgaaat ctgatgattg catacctgct
    59581 aaatgttgta ttgctcctga tataccacaa gctatatata ggtttggttt aacagtagtt
    59641 cctgtttgac ctacttggtg agaatggtct atccatccag catcaacagc cgcacgagaa
    59701 gaaccaacta ctccacctaa tttgtcagct aatttcttaa gcatttcaaa tccttctggt
    59761 ccacctaatc ctaaaccacc tgatactata acatttgcat ctgtaagaga tactaaatct
    59821 ttcttagttt taactgtttc taaaacagta gttcttatat catcttgagt tattttgtag
    59881 tctaatgcta taacttcacc agttcttgtt tcgtcttttt cagctttatc cataacacca
    59941 ggtctaactg tagacatttg aggtctatgg tttggacaaa tgattgtagc cattatgttt
    60001 ccaccaaatg ctggacgagt ttgttttatt ttcttatctt ctgggtctat ttctaactta
    60061 gtacagtcag ctgttaatcc agttccaact cttgaagcta ttctaggtgc taagtctcta
    60121 cctatatgag ttgctccgaa aagcattatt tctggtttta tttcatctat tgcatctttt
    60181 attacttttg tatatgcatc agttgtatat ttttctaaaa gagcatcatc tgcaacataa
    60241 actttgtcag ctccaaaagt gattaattct ttagctaatc catcaacatc ttttcctaat
    60301 aatattgcac aaagttctgc atctacttct ttagctaatt ttcttccttc tcctaataat
    60361 tctataacta ctggagctat ttttccttct ctttgttctg caaatatcca tacgttttta
    60421 taagaactta aatcttttat atcattcata gtttgtactc ctccaactta tataatgtgc
    60481 ttttgtttta gaccgattat tattttacta gctatttcat cagctttacc ttctaagatt
    60541 tctccttttc ctcttggttc aggagtaaat gatctaaata ctttagttgg tgatgctttt
    60601 aaaccaactt cttctttatt tacatctaaa tcatcaattg tccaaacttt tacatcatgt
    60661 ttatatgctt ttactatttt atcaacagac atgtatctag gtgtatttaa ctcttttact
    60721 gctgttaaaa gtacaggtgt acttactttt attaattcgt atccatcttc taattgtctt
    60781 tgaactatta tatcttttcc ttctattttg aaatcttgta catatgtaac ttgaggaatg
    60841 tctaatttct ctgcaatttg tggtccaact tgtgcagtat ctccatctat tgcttgtctt
    60901 cctgcaaata ttatgtcata gtcacctact ttagatattc ccgctgcaat agtatttgat
    60961 gtagcccaag tatcagctcc tccaaatgct ctatcactta ataatattgc atcatcagca
    61021 cccatagcta aacactctct tagcataaag tctgcttgag gaggtcccat tgttataact
    61081 gttatagtta catcatcatg ctcatcttta atttttaaag cttcctctaa tgcatttgca
    61141 tcatctgggt ttaatatact tggaactcca tctcttataa gagtacctgt ttctttattt
    61201 attcttactt cgttagtatc tggaacttgt tttacgcaaa ctaatatttt caaagtctat
    61261 acctccaatt tcattagatt atttattatt ttaatacgtt tgatgaaatt accatttttt
    61321 gaacttctga tgttccttcg tatattgata cgattctagc atctctgtac attctttcga
    61381 tttcataatc ttttataaat ccatatccac cgtgaagttg taatgcttta taagcaactt
    61441 catttgcaat ttctgatgca tagtatttag ccatagcaga ttcttgagca actctcattc
    61501 ctgcatctct cttttgtgct gcatcataaa ctaatcctct agctgcacaa acttttgttt
    61561 ccatgtcagc tatagtaaat tgagtatttt ggaatttagc tataggctta ccaaattgaa
    61621 ctctttgttt tgtatattta acagcttcat ctaaagcacc ttgagctatt cctagagcta
    61681 aggcagcaac acctattcta ccaacttcta gagtacccat tgctatctta aatccttgac
    61741 cttcttttcc aagtaagttt tcttttggaa ctttaacgtt ttcaaatatt aagtcagaag
    61801 tttcagttcc tcttataccc atcttatctt catgagctcc tgttgagaaa ccatcccatt
    61861 tactttctac tataaacgct gatgttcctc taagtccttt acttctatct gtaactgcta
    61921 ttactatagc tacatcacag aatggtccat tagttatgaa agtttttcta ccatttaata
    61981 tatagtggtc tccaactaat tctgctgttg tttgttgtcc acctgcatca gaaccagctc
    62041 ctggctcagt taaaccaaat gctcctatta attcacctgt tgctatacct tttaagtatt
    62101 tttgtttttg ctcttcagta ccattgtaaa gtattggtaa tgaagcaaga gaagaaccag
    62161 ctgtaacaaa agtagctgtt gaagcacatc ttctagctat ttcttccatt actatagcgt
    62221 aagaaacata tcctgctccc ccaccaccat attcttctgg gatattactg cttataaatt
    62281 ttgcatcagc taattttttg attaattcct taggcattac acctgtttta tccatttctg
    62341 ctggtaaagt atctaattct ttactaacaa aatctcttac tgcttttctt aaaagttctt
    62401 gttctttgtt atataacata gcttcctcca attttcatat tttatagtaa atttatttta
    62461 atgaacttac gctaaactca tcatctcagc aaaagtttga atacgagttc tggcttgttc
    62521 attattctga gtttgttggt cgatttcaac atataaagta ggtattccac tatcttctat
    62581 atcttttcta actaaaggat aatcgtattc ttctgggtca cagaatttca tcatacagaa
    62641 gataacacca tctatatctt tctttttaac ttcatctact ataagtgacc cacgtttttt
    62701 cttagggtca taagctaatg aacatccttc tatgtttgac cattgtcttg ctaatctctc
    62761 taacgcatca tcacctgctg gtacatctgt tctgaattgt cttgtttctt gtgctaagtc
    62821 gtcagctaca actgatatat tgttgtcttc taaaatgtct aatatatctt tagaatcagc
    62881 taatatacct gttaataaaa ctttctttcc agaacagact tcttctggca tagcatttaa
    62941 ttttgctatt aaatctttca ctagctcagt atgttcttct tttctcataa agaacccact
    63001 cttaattact aagcttctta ttgatggttt tatagtatta gaatgtttat aagctacttc
    63061 aacaaagtct ctcatagttt ttctatgttc attgtaaact tctatacttt catgaatttt
    63121 tgcttcttct atttcatatc cacaaatttc ttcaagttct ctttttacac ctttgtactc
    63181 actgattaag tattttacac cagcttcaag ttttctattt tgtgggtgta ctaatgatat
    63241 atattttata tgaggtactg ctgatttcca gttttgtcct aaacaaatta gtgtatcaca
    63301 catacctggt ataataactc cagataattc atcataagca ccttttaatc catattctaa
    63361 acatgattgc attattgaac atgcaaatgc agggaaatat tgtttagcta aatctaattc
    63421 tgtttgtcct ccccatatac caactggaag cattccagct gcatgtataa tttcttctgg
    63481 gcaataaact gggaaacaac ctatagcttt tttaccagtt tcacttttat atttttttac
    63541 agccgcattt ggattttcaa ctacttcttt cattttagat aaaatagctt ccattatatc
    63601 tcacctctat taagtttttt tctttcttcc attacttcaa ctaaaccttg aattcttgtt
    63661 tcaaattgag cattagtgaa agctctaggg tctgcttggt caccatcaaa tccagcatat
    63721 ggtaatccag tttcttcagc tgctcttctt tgcatttcat attgtattaa actcataagt
    63781 ttacagcttc tgttcatatg atagaatgct ccatcacatt taccctctac taaagaatca
    63841 actctatatt ttgtcatacg gtctaggttt acattgttaa acatagtact atatgctact
    63901 gccattccat ctaaatcatt aacttcatat tgtaatgccc aagcatgtgg gtaaacacta
    63961 cctgtcatgt taactccaaa tttagctaat gttttcatct tgtatcctat atatggccaa
    64021 caaggtatac cttccatcat tattctgtat ttttcttccc ctctgaaaga agatttacca
    64081 gttttcatgt tgtcctctaa ttcttctata agtaacttaa atgcttctgt agtttctttt
    64141 ttacctctag cacaaactat tacagccatg taagtaaata agtcaaatcc attcattgga
    64201 gaaggagaag aatctgctgg taaactcata gaatacttcc atagtcttcc gttttcagct
    64261 gatattttca ttacttcttc aaacttctta gggtcaaatt tctttcctga tataatttct
    64321 agttgtttta tagcttcttc aaattgagct ttaatataat ctattcttga ttgagtaact
    64381 tcgtcttcat tattgaaagt tgtatcaatc attattaaag gtatatctaa ttctcttgaa
    64441 atattttcat accattttat aacttggtta catatattgt tacagcaaag taggaaatct
    64501 ggagccggca tatccaaagc ttcacatcca ccattttcta aaagaccaaa atttgttctt
    64561 gcatatgcac ataggtcaat agaatatcct ttagattcag ctatttcaca taattctaaa
    64621 gaaccttttt tagctgctac tccagctgct tggttttctg gatataatac gtttaagtca
    64681 aatacttctg ctaactcttg aggaaatact gatgttgacc aacctacagg tcttccttct
    64741 tctttagctt taaatgcatt tgcatattgt tcagctaata aatcattaat tactactcta
    64801 gcttcttttt tttcagacat tttcatccct ctttttatat atttttcact tctttttgtg
    64861 attcttttgc ttcatcaaaa gcatataacg ctgctcctaa agcaccagtt aattgaggta
    64921 tatcaggtac aataatttct gtgttgattt ctcttgccat agctcttaca ataccactat
    64981 ttctagcaac tccaccaacc ataactacat ttctttgtac tcctattctt tttactaggc
    65041 tagaaactct ctttgctact gaagtatgaa tacctgccac tatatcttca atttttgcat
    65101 tttcagataa atgtgatata acctcagact ctgcaaatac tgtacatgta ctgcttattg
    65161 atacttcatt ttgagaattc atagatatac ttccgagttc agatacatca acctctatta
    65221 tttttgccat tacatctaaa aatcttcctg tacctgcagc acatttgtca ttcataagaa
    65281 agtttaatag tcttccatta ttatctaatt ttaatacctt tgcatcttga ccacctatgt
    65341 caataatggt tcttgtctct ggaattatga aatttacccc tctagcatga cagcttaatt
    65401 cacttatttg cttatcagca tctgaatagt tcattcttcc atatcctgta actacaactt
    65461 ttttaatatc ttctcttgca agacctgtct tgccatataa tttttctaaa actcttgatg
    65521 gtccagtagt cccagtacca gaggatattg tttcagaagc tacaatatct tccccattct
    65581 ttaagattac tccctttgat gcagttgaac ctatatctaa tcccattgtg tacatcttta
    65641 gcattctcct tttaaaaaat ctagaattac taattaatat cttacaactt tactatcttt
    65701 aaagttattt attttctctt catcgtagcc taaagatttt aatacttcta cagtatgttg
    65761 acctactttt ggtgctggtg tatattcttt aattccttca tttctaaaca taactggagt
    65821 attaactaag acacctgtat ttccgctatc gtatgttttc ttaaataaga agtcatttgc
    65881 ccaagcttgt tcgtcatcta ataaatcttc acagctttga attttttcaa atggtaagtc
    65941 tgcttcttct aataaagctg accactcgtc taatgttttt tctaacatag cttctccaac
    66001 tatcttaact aaatcttcaa catgattaac cattgaatct atgttattat atctatcgtc
    66061 ttctaatata tattctctat ttataacctt acagaatttg cctaaccact tgttgtattg
    66121 tattaaagct aattgaatcc atcttccatc tttacattta tatgtagtca ttaatgggct
    66181 gtttggattt tctcttgata aaggcatttc atttccgtat tgtgctgttg ttatcattgt
    66241 tcccattcca tatatagctg tatggaaaag acttactgtt actctctcac ctttaccagt
    66301 ttgagctttt ttatgtaatg ctgctaaact tcctgctgct agtgctagac ctgcatagtg
    66361 gtcaccaaat cctgctgctg tatttgctgg agatgttcct ttttccataa cagattggct
    66421 aactcctcct cttgcgaagt atgcagtata gtcaaatcct ggtttatctt ttaaaggtcc
    66481 tttttcacca tatcctaata tttgagagaa tattaatcct ggatacttat cttttatttg
    66541 gtcataagct atacccattt tttctaatgc ttgaactcta acattagtta caaatatgtc
    66601 tgcttctgat aataatttat gtaatatttc tactccttct tttgatttta cattaatact
    66661 tacacccttt ttatttccat tttctaattc aaacataggg ttttcatcat ctgatgctgg
    66721 agatttaaat gttccaccca taactcttat tccatcacct tctataggtt caatcttaat
    66781 aacctctgca ccccagtcac ctaacatttt tgcacaacat ggtgctgcga tgaaacttga
    66841 aagttctact actttaactc cttctaaaag cataacgttt tcctccttaa tagtatcaat
    66901 tataaaattt cgattaaatc actcataaaa tacttttttc tgatattaac tgtctgatgt
    66961 caaagttcct aatcttatct aaaataactt aaaaattatt aaaattattt tttattgttt
    67021 tattgtctta cacctatatt gttaagcatt tatcgtgcca actttatatt taatcaaaat
    67081 atcgcttgat ttgaatgttt tttaacaata tgcaattgaa taatcttttt catatcgtgg
    67141 catcttgcca ctatccattg cattttgcta ttctttctat gcttataaaa gtttttttta
    67201 tatatttttt tatgaaaaag cttgacattt caaaaaaagt tttcattgct aaactcaaaa
    67261 acacatgtta tcattgtaat taatcagcaa gttagttaac taatttcaaa cttagataat
    67321 tttttaataa tatttaatct aaaaaataac aatttctttg ataaatttta gagtaattat
    67381 tacattaaat aaaaaattac taaatatcaa aataacacag ggaaaacaat ttcaaaacta
    67441 aatttttaac cttaaaaatt ttgtataaaa aatataacct tatatgctac atattatttc
    67501 taaatgaaaa attaccataa taatttaata attacaggag ggtattgata tgaaaatact
    67561 agtatttgga gcacgcgatt atgaagaacc agtaataaaa aaatggtctg aagaacataa
    67621 ggatgttcaa gtggatattt atcctgaaaa catgactgaa gaaaatgtag ttaaagctaa
    67681 agggtatgat ggtatatcta tacaacaaac taactatata gataatcctt atatttatga
    67741 aactttaaaa gatgctgggg ttaaagttat agcttcaaga actgcagggg ttgacatgat
    67801 acattttgat ttagttaatg aaaatggact tatcgttaca aacgttcctt cttattcacc
    67861 taatgcaata gctgaattag ctgttactca agctatgaac cttttaagaa agactcctct
    67921 agtaaagaaa aaagtctgtg aaggtgatta ccgttggata gctgaacttc ttggaacaga
    67981 agttagatct attacagttg gtgttatagg tacaggaaaa ataggtgcta cttctgcaaa
    68041 attattcaaa ggcctaggag ctaatgtaat tgcatttgac caatatccaa atagtgattt
    68101 aaatgatata ttaacttaca aagattcttt agaagacctt ctaaaagaag ctgaccttat
    68161 aacattacat actcctttac ttgaaggaac aaaacatatg ataaataaag atactctagc
    68221 tataatgaag gatggagctt acatagtaaa tactggccgt ggtggtttaa ttaatacagg
    68281 ggatttaata gaagcactag agtcaggaaa aattagagct gctgcccttg atacatttga
    68341 aactgaagga ttgttcttaa acaaaaaaat gaatcctgga gaattaactg acccagaaat
    68401 aaataaactt ctttctatgg aacaagttat attcactcat caccttggtt tcttcactag
    68461 tacagcgatt gaaaatatag tttattctag tttaagtagt gctgtagaag ttataaaaac
    68521 aggaactgct actaatagag taaattagta ttttataaat atattttttc attaattagc
    68581 tattatctaa caaaatagcc tttaatttcc caaatataag agagtcagct cagtatatat
    68641 tgagtagact ctcttatatt attttttata ttaaacttgt actcttctta ttcataccaa
    68701 attaaattta tattaactta ctctaactac tcctactcta tacattttac ctatttttac
    68761 ttttctaatt atatacattt gaatgggtac aatctgtatt ttacaaaaaa aacacctaac
    68821 aaactatgaa aattgtatga ttaatattaa tatatttata agaaaacata acaattatgt
    68881 tagctctgga tttttaggga gggagtatat tggaaaaaat gaataaagtt acttctaaaa
    68941 aaactaccta tattgttact tcagcattat ttgcatccat aatatgcctg acaatagcat
    69001 atatattaca tattccagtt ggtggaaaca atggatatgt tcatatagga gatgctttta
    69061 tttatctagc tgcaactatt ttgccaacaa actatgctat agctgcttct gcaattggtg
    69121 ctggtctagc tgatttatct acaggtgctg ctatctgggt aataccaact ataatcataa
    69181 aaccaatact tgtattattt ttcacttcta aaagtgacaa gataataaat aagagaaata
    69241 tagttgcttc ggttgtagca ggtatagtag gattagtttt atacatgttt gctgaaggta
    69301 taattattgg aagttttaca agtgcatttg taatgagctt acttggctta ttacagccaa
    69361 taggaagttt tattgttttt ataatcttag gtatggcact tgataaactt gattttaaaa
    69421 aacgttattt taattaagaa tttaaattta tggagggaaa attatgaata tcttatatac
    69481 aattgaaaat agtatctatg taaatataac taatacatgt ccatgtagtt gtgttttttg
    69541 tataagaaac gaaaaagatg aagttgcaaa tagtggtagt ttatggttgg agcatgagcc
    69601 aagtgtagat gaagtaaaag aagccttcaa taaatacaat ttagacgact atgatgaaat
    69661 cgtattttgt ggatatggcg aaccattaat gagaataaat gaattgatag aggtagcaaa
    69721 gtttataaaa gaaaaaagta gcataaagat aagaataaat acaaatggtc taagtgattt
    69781 aatacataac aaaaaaacag ctattctgtt aaaaaatgtt atagatgcag tatcaataag
    69841 tcttaatgcc ccaaataaag aagcttataa tagagttact caaccaaagt ttggagaaaa
    69901 atcatttgat tatatgttag attttgcaag agattgcaaa aaatatataa aagaagtagc
    69961 tttttcagta gtagatgaaa tatctccaga agaaatagaa gaatctaaac aactggcaaa
    70021 aaaacttgat ataccattaa gggttagaca taagaattag caagtaaaat tataaaacat
    70081 taagaatcac ctgaatggtc tttcaggtga ttcttcctct tgtattaaca ttttacaaaa
    70141 tagatttcat accacactag gaatgtgtaa atcatccaaa tctttctcca attatcagag
    70201 tttccactaa tgtagtcatt aaaaatctca ttaatctcat ctatgttaaa gaatttatct
    70261 gctatctcac tattgaattt atctcggata tccttattat attggtcatc agccatccat
    70321 atacgaattg gcacaataaa tcctaattta tttctaaaag caatctcttc tggtaatgtt
    70381 tttgatgcag ctgtacgaaa ggcaatttta ttctcttttc ctttcacttt atattctgat
    70441 ggtattctgg atgcaatatc aaatattctt gtatctgtaa gaggcattct gacttccaat
    70501 cctactgcag tactcatttt atctatatta aaataaatat ctccttccaa ccatatttga
    70561 atatctacat ttgacatgtt agtaagtgta tctagttctt ctgtttcttc ataaattcct
    70621 tttaccactt caataggaag cacatcagga ttgtatttct taagaatttt tcttttctca
    70681 ccctcattca taatgtttgt atttccaata taaaatgtct tcaaattctc tccataacac
    70741 tctgccttat ggtatatatt atatccacca aaaaactcat ctgctccttc tccagagtaa
    70801 cagatatttg tgttttcagc tgctgccttg catccaatag caaaaacgat agcagatgca
    70861 tctccagttg gttgctccat atggtacatt acataaggta ctgacgcaaa atactcttca
    70921 ggtgtaatta tatatctcga atttttacac ccaagaatat tagctgtctg ttgtgctaat
    70981 tttgattcat caaaacgctc ttcctcataa ccacatgaac ctgttttttc tatatctgac
    71041 attgccaata tataagatga atcaacacct cctgatagga ataactctgc agtttcattc
    71101 tctgatttta cctctggcat aattttctga agtgttgtat gaatttcatc cgtccattcc
    71161 tcaatagact tgctgtggtc aggatgaaat tcaggtttcc aataacgacc aatacatact
    71221 gttttattct gatagacaag gtaatgtcct ggcataagct tctttactcc acggaagaat
    71281 gtattttcac ctgctacata tgtgaaagac atataaatct gtaacatgtc ttcatttaac
    71341 tctttcacaa atcctggttg ctccataatc ttacgaatag atgaaccata gagaagcttc
    71401 ccattttcag tctcataata atagaaaggt tttaccccaa actggtctct taggcagaag
    71461 agtttctttt ccacagtatc ccataatgca aaagcaaaca ttccatgcat gtgatttgcc
    71521 atatcatatc cccatgtctt atatgcttcc actaaaattg ctcgttcacg ctcatctcta
    71581 cataatgaag aatcgattcc aagttcttca caaagaactt tccagtttcg aatatgccca
    71641 ttgtattcta gaatttttat catatatgtg tcttttcgtg ttaaatactt ttcttctaaa
    71701 tttatcatat gtgtatcctt tcgtattaaa acatttaact tctaaattta ttaaatgttt
    71761 atatatattt attcacttat aatcactgaa aaatcgactt ttttcaaagt aaattctttt
    71821 tgaattagta ctaatctgct ctttattaat ggcataaata tgattatcaa gtattatcag
    71881 tgttataaca ttgaattttt tattcttcat aa
//
LOCUS       DAJMZY010000006        63642 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.006, whole genome shotgun sequence.
ACCESSION   DAJMZY010000006 DAJMZY010000000
VERSION     DAJMZY010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 63642)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 63642)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..63642
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.006"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            complement(130..324)
                     /locus_tag="OE968_000375"
     CDS             complement(130..324)
                     /locus_tag="OE968_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7217692.1"
                     /translation="MFQVINFLCLFCVGFLVLDVMIYFCKDAMDIFEGTTNVNKVKSI
                     NVWADRVRANSYSYENKIAK"
     gene            complement(633..2162)
                     /gene="lysS"
                     /locus_tag="OE968_000376"
     CDS             complement(633..2162)
                     /gene="lysS"
                     /locus_tag="OE968_000376"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HCP7217693.1"
                     /translation="MKNNQQSNEEAQIQEDLSEVLQVRRDKLKKLQESGRDPFKESRY
                     DRTHYSMDIKDNFDSLEGKTTKIAGRIMSKRIQGKAGFIDIQDQEGRIQSYVRLDAIG
                     EEEYSVFSTYDIGDIVGIEGEIFKTKKGEISVKAKSVVLLCKSLQVLPEKYHGLKDQE
                     LRYRQRYVDLIVNPEVKNAFLIRTKALKALRAYLDDRGFLEVETPILNTIAGGANARP
                     FITNHNTLHIPMYLRIANELYLKRLIVGGFDKVYEMGRMFRNEGMDLKHNPEYTAIEL
                     YQAYADYTDMMEITENVIAHMAEVATGSMIVNYQGTEINFTPPWKRMSMEDCVKEYSG
                     VDFSTINTDEEALEVAREKGIEIKPGMRRGEVINAFFEEFGEDKLIQPTFITHHPVEV
                     SPLSKRNVEDPRRTDRFEAFANKWELANAFSELNDPIDQKGRFIDQLRKRELGDDEAF
                     EMDEDFLKALEVGLPPTGGLGIGIDRVIMLLTNSPSIRDVLLFPTMKPIDNNPNKEEE
                     N"
     gene            complement(2177..2656)
                     /gene="greA"
                     /locus_tag="OE968_000377"
     CDS             complement(2177..2656)
                     /gene="greA"
                     /locus_tag="OE968_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003514606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HCP7217694.1"
                     /translation="MEENKEFLLTQEGYDKLEEELENLKVVKRKEVAERIKVAISFGD
                     LSENAEYDEAKKEQAQVEERILKLENMVRKAVIIDESKIDLNVVTIGSIVKVKDLEFD
                     EEVEYTIVGSTEADPYDGKISNESPVGKALLGRAAKEVVEVQVPDGVAKFEILEIRR"
     gene            complement(2765..3733)
                     /gene="dusB"
                     /locus_tag="OE968_000378"
     CDS             complement(2765..3733)
                     /gene="dusB"
                     /locus_tag="OE968_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HCP7217695.1"
                     /translation="MKIGNLELKNKVFLSPMAGVTDLPFRLICKEQGCGLLYTEMING
                     KALCYDDENTKKMLKIEEEEHPVAVQIFGSEPEFMGRAAEIMNDYSNEILDINMGCPA
                     PKVVKNGDGSALMKNPKLAEEVLRAVVKNSKKPVTLKIRKGWDDNSVNAVEIAKIAED
                     CGISALAIHGRTREQFYTGKADWDIIAEIKKNLSIPVIGNGDVFTIEDSINMLDKTGC
                     DAIMIGRGAQGNPWIFKRINHYMNTGEILPEPTLNEKISTAIKHLKLAVEEHGEYVAV
                     REMRKHIAWYLKGLRNSAKLRDEINKIEDYQEVVSKLEYYMEDSLT"
     gene            complement(3870..4640)
                     /locus_tag="OE968_000379"
     CDS             complement(3870..4640)
                     /locus_tag="OE968_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III pantothenate kinase"
                     /protein_id="HCP7217696.1"
                     /translation="MLLVFDVGNTNMVLGIYKGDKLVNYWRIKTDREKTSDEYGILIS
                     NLFDYDNVNISDIDDVIISSVVPNVMHSLENFCIKYCKKQPLIVGPGIKTGLNIKYDN
                     PKQVGADRIVNAVAGIEKYGAPSILVDFGTATTFCAISEKGEYLGGTIAPGIKISSEA
                     LFQSASKLPRVELAKPGMTICKSTVSAMQSGIIYGYVGLVDKIISMMKKELNCDDVKV
                     IATGGLAKLIASETKSIDYVDGFLTLEGLRIIYEKNQE"
     gene            complement(4659..5249)
                     /locus_tag="OE968_000380"
     CDS             complement(4659..5249)
                     /locus_tag="OE968_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HCP7217697.1"
                     /translation="MMNTSASVRKVNVRKMTIIGVLSAISIMLSMTPLGFIPVGPTKA
                     TIMHIPVIIGAIMEGPIVGAAIGFIFGISSLLNAITNPTVTSFVFINPLVSILPRVMI
                     GVLAYYVYQLIIKATNKVYISGLITGAIGSLLNTAGVLGMIYVLYADKYLHAMGKSGS
                     AGKVIMALAAANGVPEAIVGALVVAAVATVLKKSKK"
     gene            complement(5433..6401)
                     /locus_tag="OE968_000381"
     CDS             complement(5433..6401)
                     /locus_tag="OE968_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P1 family peptidase"
                     /protein_id="HCP7217698.1"
                     /translation="MYNNILDIEGLKVGQVEDRNGLTGCTVVICEEGATCGVDVRGSA
                     PGTRETDLLDPVNMVQKVHAVVLAGGSAYGLESTCGVSRYLEEKGIGFDVGVGKVPIV
                     VGAVLFDLGVGSFKCRPDLKMGYRACEVANTDILNQGNYGAGCGATVGKIRGQEYAMK
                     GGIGSYSIKLDNGLIVSALIAVNALGDVYENGKVIAGALNDKKTETIDTYKLMKQGES
                     KGGFSVDNTTIGIIATNAKLTKAGCKKISQMGHDGYAKSIFPIHTPHDGDTIFTISTG
                     EIEADITLVGSLAVEVVEKSIINAVKKADSVENIMAYKDIVKKREI"
     gene            complement(6394..7371)
                     /locus_tag="OE968_000382"
     CDS             complement(6394..7371)
                     /locus_tag="OE968_000382"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HCP7217699.1"
                     /translation="MRDKIIEIILNNKSEFISGEELSKQLGVSRAAIWKHMKALKEEG
                     YNIESVNKKGYRLAENPTDLLSPQNIYYKLDTEFIGKNIEHLDTIDSTNEHAKRIAIN
                     SVDGTVILSEHQDMGKGRLGRRWDSKPHEGIWMSIILKPDMEPFKAPFITLIAGASVT
                     KALNNLGANTLIKWPNDVILNGKKICGILTELSAEIERTNYVVLGIGINVKIMDFEQE
                     IADKATSLYKEGYMLSRVDIVRNVLTEFEKLYLDYTVNNSKEKTLKICRDYSAIIDKN
                     IYVLKGDNRELVKCLDINEEGNLLVQRSDGSIKEIISGEVSIRGEKGYV"
     gene            complement(7686..9656)
                     /gene="ftsH"
                     /locus_tag="OE968_000383"
     CDS             complement(7686..9656)
                     /gene="ftsH"
                     /locus_tag="OE968_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HCP7217700.1"
                     /translation="MNKLLKGAGFYLLVFIIIVGIVQFSGKPTEKIKDLKFSEVYREL
                     TDENISRLYFVNQTSVEGTIKDTNTKFKSYVPTEVMGNKLADEVLDQAKAGKLTFGGE
                     AKPSTPWFVEMLPTLLLIFFMVIIWFVFMNQSQGGGGKVMSFGKSKAKVHKDDEKTRV
                     TFKDVAGLDEEKEDLQEVVDFLKNPKKYIELGARIPKGMLMVGPPGTGKTYLSRAVAG
                     EAGVPFFSISGSDFVEMFVGVGASRVRDLFEQAKKSAPAIIFIDEIDAVGRKRGAGLG
                     GGHDEREQTLNQLLVEMDGFGVNQGIIIMAATNRPDILDPALLRPGRFDRQVVVGTPD
                     VKGREAIFKVHSRNKPLSDDVKMDVLARRTPGFTPADIENLMNEAAILTARKREKKIK
                     METIEEAITKVIAGVAKKSKVISEKERRLTAYHEGGHAVCAHVLEEVSPVHQVTIVPR
                     GRAGGFTMQLPVEDKFYATKNEMKENIVVLLGGRVAEELVLKDVSTGASNDLERVTAT
                     ARSMVTKYGMSSKLGPMSFDSDDEVFLGNSFSSKRNYSEEVAFEIDQETKRIVDGAYD
                     KTRSILQENMDRLEYVAQALLIYETLDAEQFVKAFNKELPLNEIENAVTEENSSKEVE
                     EQLTIKLEKDEEERNNVIDINKNLEDKSDKDK"
     gene            complement(9690..11078)
                     /gene="tilS"
                     /locus_tag="OE968_000384"
     CDS             complement(9690..11078)
                     /gene="tilS"
                     /locus_tag="OE968_000384"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HCP7217701.1"
                     /translation="MIFDKVLSTINKHNLIQKGDKIVLGLSGGPDSVCLLHVLNRLKK
                     DFNIEIYAAHLNHQIRGIEAQKDALYVSKLCEDMGIIFFVKSINVPKYCENEGLSLEE
                     GARKLRYEMFYEIKDKIKANKIAIGHNLNDQAETVMMRIMRGTGLKGLKGIDYIRDNC
                     IIRPILDVERNEIEEYCEAYNLNPRIDKTNLENIYTRNKIRLDLLPYMKDNFNSNVIE
                     SIVRMSNSLKSDNDYIEKEAEAKFREVSNIKEKGFVEINLDDFVCLHDAIKVRVLRNS
                     IKHILGDTNFVDQRHIEDIMSLEDNSKVNKMLTLPRNIFVYRKKDSIILTNEEIVNEE
                     IEFYYNVPSNGFIKIKELKQIIETQVMSIDRYKSMKLDNSSKGFDFNKVKGGIVIRSR
                     RQGDKIKLAMGSKKVKDLFIDLKIPREERCKIPIITDSEGIICVGDYKISENYKIDEN
                     TKEVLKINFNKL"
     gene            complement(11261..11689)
                     /locus_tag="OE968_000385"
     CDS             complement(11261..11689)
                     /locus_tag="OE968_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HCP7217702.1"
                     /translation="MEEKSLSVKISINTRQYDEKGNMDTIEMTAFGKIFYKNDGIYVI
                     YKEKEEDIEITNTIKILKNQVSIKKFGAINSTMLFKCGESSTTKYVTPQGTLLIDIDT
                     RELDINIQEGEHIKLKIDYNIKVQDLFLGRNKIDIYIGTK"
     gene            complement(11706..12512)
                     /locus_tag="OE968_000386"
     CDS             complement(11706..12512)
                     /locus_tag="OE968_000386"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HCP7217703.1"
                     /translation="MNNKPIGVFDSGLGGLTVLKEIMKILPNEDIIYFGDTARIPYGS
                     RSKETIIKYTFQAINFLKTKGVKAIVIACNTATARSLKEAQEKYDIPIIGVIEAGART
                     AVSSTKNKIVGIIGTEGTISSKAYNLEISKIDESIEIVNKACPLFVPIVEEGWANTEV
                     AKLTAKIYLQELKEKNIDSLVLGCTHYPILKRTIGEEVGEHIKLVNPAKETAKDLKKI
                     LEVQNIINNTEIHGTYQYYVSDIPEKFSDIAREFLKKKIDKIQKVEIQKY"
     gene            complement(12714..13199)
                     /locus_tag="OE968_000387"
     CDS             complement(12714..13199)
                     /locus_tag="OE968_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase"
                     /protein_id="HCP7217704.1"
                     /translation="MATLLALTFIFMPIKEVFAYEPTENIKKVNKQEKNIAKKEVINL
                     SDNDLMLLSKLVAGEARGESYEGQVAVAAVVINRVLDPRFPDTIEEVIYQKNAFSVVL
                     DGSIKMAPTDSARKAAQEALYGTDPTNKAVYFWNPEIATCKWINRLNPYMRIGNHVFA
                     K"
     gene            complement(13250..13909)
                     /gene="spoIIR"
                     /locus_tag="OE968_000388"
     CDS             complement(13250..13909)
                     /gene="spoIIR"
                     /locus_tag="OE968_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein R"
                     /protein_id="HCP7217705.1"
                     /translation="MRKIKIRLGLLILSLISVISIMTIVINGEVKKVDNISKDYKDKL
                     IRFHVIANSNTDEDQELKLKVRDEVIKYLQPKLQNSKSIKESEAIIKKEYSSLEEISK
                     NIILKNGYNYSVKVGIQYSNFPTKQYSNIVLPAGEYKALKIIIGKGEGKNWWCVMFPP
                     LCFVDESNGVIDKSTDDKLKEVLTDKEYKLIKQDTPKKTSRVKIKFKVLEVVKDLEKK
                     F"
     gene            complement(14054..14734)
                     /locus_tag="OE968_000389"
     CDS             complement(14054..14734)
                     /locus_tag="OE968_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCP7217706.1"
                     /translation="MENLTKLNLDNYKPLRDVVFENLREAILEGKLKPGQRLMEVQLA
                     EQLGVSRTPVREAIRKLELEGLVVMLPRKGAYVANMSLKDIMDVLEVRASLEGLAAYL
                     AAERISDEDIKKLKDISEEFKKSTLESDVDALLKLDVEFHECIFKATNNKKLIQLINS
                     LWEQVYRFRVTYMSAYDTSHNIVEEHKYLLDAIIKGDSELSKKYATEHIEKAEQFMID
                     KAMISKDL"
     gene            complement(14718..15608)
                     /locus_tag="OE968_000390"
     CDS             complement(14718..15608)
                     /locus_tag="OE968_000390"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HCP7217707.1"
                     /translation="MDFIRLKSRAKINLSIDVLGKRQDGYHFVEMIMQTIDLYDIVKI
                     KELDEDEIKVKSTSLDIPLDEDNIVYKAAKILKNKFYIKKGVEIFIEKNIPVAAGMAG
                     GSSNAAAVLVGLNHLWELRLSEDELKEIGLNLGADVPFCISGRPALAQGIGEKLTNIK
                     GLPCDTNILICKPDLFVSTKEVYQGLDLNNIKKRPNNKYLIECLKSEDIKAVSESMVN
                     ILENVTIGKHKEISDIKQVMMKNNALGSMMSGSGPTVFGLFKNKEDALIGKKELLKKY
                     KQVYVVNSSQKGVEICGEFN"
     gene            complement(15726..17276)
                     /locus_tag="OE968_000391"
     CDS             complement(15726..17276)
                     /locus_tag="OE968_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3794 domain-containing protein"
                     /protein_id="HCP7217708.1"
                     /translation="MELIKDVIKVDNRIDFGKFQTFIEAEAVVPDKKLDVYEIVKTEG
                     YISLKKIEMADGKILCRGSFNYNVIYIADDKNTISNVDGKVDINEVIEKDNVVQDMEY
                     MLFSEVEHMDCTIMNERKIKVGALMNIRGSLFEKQRLDIVKDVAQVEGIQKHRKEICF
                     QDIVGIEKAESSIRDTITINTEEIQSIISLNPCVKVKESRVTDNKVIIGGVLEINPLA
                     CTYEGELVELDRVGIEFTQFVEVPGVSDGMTEEVLLSMSDFNHIFKQNSESNTGLLEI
                     DCMACCKVKVTDEVTREVLQDAYSPQKIIKFDHKPIQLNKTLRRSEETFMVREGIRND
                     NDDIQIKDIVSVCPTMSIENSYIEGNKSIIQGIIKVEILFVPVEGLKLVYKISEEIPF
                     EHDIEMDNLTDTASVFNTACIDKVEVDLNRDQIDLIIKIKRFTEALDKKAENFIIKGE
                     DQGVYDLSKAPSIIVYICKEGDTFWNIAKKYNTTENEIAELNDIKLDEPIKPGKCLIL
                     EKKVVLVD"
     gene            complement(17370..17636)
                     /locus_tag="OE968_000392"
     CDS             complement(17370..17636)
                     /locus_tag="OE968_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HCP7217709.1"
                     /translation="MATVQTLDKIRVSLERHIGKKILLKANKGRKQIITKEGILEKVY
                     PSVFVIKLDDESNGYPRVSYSYSDLLTSNVKLQVFRDQDKLQIS"
     gene            complement(17784..18644)
                     /gene="yabG"
                     /locus_tag="OE968_000393"
     CDS             complement(17784..18644)
                     /gene="yabG"
                     /locus_tag="OE968_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation peptidase YabG"
                     /protein_id="HCP7217710.1"
                     /translation="MKVGDIVARKSHNKDIVFKIVSFGVDENNEKIAILKGIAFRVIA
                     DAYIDDLELVKAPDIKDILIDKNVENLLYKSVRKAKERQKRMTRAVPKLQLNPNTYGM
                     PGKVLQIDGDKEYLKICLDVYAQLGIPAVGVAVSEQNQYKEVRALLEKYNPDILVITG
                     HDAMTIKRGDIEDMSNYRNSSNFVKTVKEARKWQPNLDNLVIFAGACQSNYEKIISAG
                     ANYASSPGRIMIHALDPVFIVEKIACSRIDVVVPIDEVIEQTITGVKGIGGSETRGKF
                     RWAMPKTILH"
     gene            complement(18728..19666)
                     /locus_tag="OE968_000394"
     CDS             complement(18728..19666)
                     /locus_tag="OE968_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HCP7217711.1"
                     /translation="MKFIDLHCDTIAKLMENVETSELKSNKYSVDIDRLKKGDSLAQT
                     FALFVDTEEVKHPFDYCMSMANKFHEEMKKNSDEIALATNYEEIMKNQSEGKLTALLS
                     IEEGAVLEGKLENLKKFYDLGVRMMTISWNHVNELSFPHNKVEYREKGLTDFGREVVH
                     KMNELGMLVDVSHISDGGFYEIAKISSKPIIATHSNSRAMMNHSRNLTDDMIKVLANK
                     GGVTGINFFHLFLSDKSESKLEDMVRHIKHIVNVGGIDVVSLGSDFDGIDSKVEIEDI
                     SQMGKLYEPLKKEGFSEDDIEKIYYKNALRVIKEVL"
     gene            complement(19776..19937)
                     /locus_tag="OE968_000395"
     CDS             complement(19776..19937)
                     /locus_tag="OE968_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7217712.1"
                     /translation="MFILRFADDDDNLSVKDFTSLTDLKKYISENNIDKTWHQIEEVK
                     KVIPNLKEE"
     gene            complement(19947..20444)
                     /locus_tag="OE968_000396"
     CDS             complement(19947..20444)
                     /locus_tag="OE968_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SEC-C domain-containing protein"
                     /protein_id="HCP7217713.1"
                     /translation="MSLYTEWRNLSDNHESQEAEVKFWEEYLKVEAGIYNEILNNKMD
                     VVEGKVSELAEKFGTTNEFFMGFIDGISESLKEDIVLEEVEADKEVSIKIDWEKLYNN
                     MVTVEAHWLYNLQGWEDILPADQRKEIIKAYKKSKTIVKEAKIGRNDSCPCGSGKKYK
                     KCCGK"
     gene            complement(20559..21269)
                     /locus_tag="OE968_000397"
     CDS             complement(20559..21269)
                     /locus_tag="OE968_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0489 family protein"
                     /protein_id="HCP7217714.1"
                     /translation="MENYEYSGFYIEKPVGNNVFSYDKRENKSIYVPKLINGTLNDVR
                     LGNEVVFNEVDENKEIKAKGLENMVEYVLGNKKIYVFDNHNHAFYFWAKSLLKGEFTK
                     GCKLVHVDQHKDTREPENYDVDVNNLKDVFRYTNEVLNVGSFIKPALKYNIFSELIII
                     DSLYGFDLEVESEFVLDIDLDIFSSDMDYIPFELKFYKIKNLIKKAKVITIATSPYFI
                     NQEYAIKVLKELFNYDII"
     gene            complement(21445..21975)
                     /locus_tag="OE968_000398"
     CDS             complement(21445..21975)
                     /locus_tag="OE968_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7217715.1"
                     /translation="MDIRALPIRITKEEAIEIAKSGKNSLFSKLILKNKYAHEVRLHY
                     IEFKIITLKIHKTKSIFKNRRYSNDINELKILVNGSTGSGSIVQDFPTYEVVKNVDCN
                     IVQYSDKDERRVKAKANKMAMRLTHRFMGGIPEIEIVKIESIFRPYWVVFFGKVELNR
                     RVSYLPIEADGFVIGM"
     gene            complement(21992..22222)
                     /locus_tag="OE968_000399"
     CDS             complement(21992..22222)
                     /locus_tag="OE968_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7217716.1"
                     /translation="MSKLVSKVKKDLEIKWLGIDGFLVLLYFLITGFIFYGILTRNDI
                     IVGKIIPYGVMSVVIVIFFDYIYRVLKMTRKK"
     gene            complement(22237..23631)
                     /locus_tag="OE968_000400"
     CDS             complement(22237..23631)
                     /locus_tag="OE968_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter family protein"
                     /protein_id="HCP7217717.1"
                     /translation="MLTFWENGIIVIFAFILLGIGYYFSRNVKDMESYYLGNRSLPWS
                     LIVGTLVASWYGGVGTVGSVEYAAIYGISAWAVWSIAAHIGRMPLALWVGPRIHIRTN
                     ITVPDLLESFYGKHVAIIGAILMFIYCAQLGEITAMGTIGNVAWKIDKELIGLIMVGV
                     VVVLTVLGGLMGVAITDMVLFFCMVFGLTMVMPGQFEQIGGFQGLTEALKDAPQLMHP
                     TKGMSAMKALMLIVYSFGAYSDPTFYQRFSAADSPKVGRRALLTCFSLWICFDMVLTM
                     TGLIVRATYPEMAPAAGYITLVLDTLPQGIRVIFIIGILGSIISTLDSYYLAAGATLA
                     NDIYGRITKKELSQKQLVKFTRIGVCLAAVMGLSVAFRFENVYDACIFVGSIWMGSAF
                     VPIVGGLLGNGRRTSMGGILGMIVGGVTFGYFKIFPVQSFELEPLVIAIPFSFIAWMI
                     GNRIGENLNTQNNL"
     gene            complement(23757..25010)
                     /locus_tag="OE968_000401"
     CDS             complement(23757..25010)
                     /locus_tag="OE968_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCP7217718.1"
                     /translation="MESKNNVKRFLIIFILAFGTTAMYSLPYMKSSFYDPMQQALALS
                     HTQIGNLLSLYGLVGMVSYFIGGWFADRFSVRKLITFSLIASGILGFYFSTFPSYSMI
                     LLIFVLWGFTTILTFFSASVKVVRMQGSESEQGRIFGFYEGLSGVSGTLISFIGLYFF
                     GKFAEITVGFKYVVWLYSAASIICGILLFFLVEEKKDSGASDEGLSIKSLLKVVTMPK
                     AWLIGLIIFSTYLVFSSLTYLSPYLSEVYVMPMTLVSALSIIRTYVIKMGASPVAGVI
                     TDKVGSSIRVMFVGFILMTVSTAAYLVIPKSTGFIWIAVINMIILSVILFGFRGIYFA
                     SVSESNISLETTGAVVGFASFIGFSPDAFYYTIAGNWLDKYGQTGYTYIFILSVVCAV
                     IGIFATYALNKINKRENKGLNNKIA"
     gene            complement(25061..26215)
                     /locus_tag="OE968_000402"
     CDS             complement(25061..26215)
                     /locus_tag="OE968_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HCP7217719.1"
                     /translation="MSNNINQDLETKIIHWGHSADPTTGALATPICQTATFAAKTVEH
                     FEELCMTWGYVYTRECNPTLTELEAKLAMLENAESAISSTSGMGAITSTILALVKSGD
                     HIVSSDGIFSHTKLFMSELLSKFGVEVTFVDAVNPQNVKEAMRPNTKIVYIESPLNPS
                     LDLVDIKTIAEIAHENKSLAIVDSTFGTPIVQRPIDLGADLVIHSLTKFINGHGDTLG
                     GAVAGSKELIDLVRWPSLCCFTGASLPPMSAWMILRGMKTLDMRMKKHCENGLAVAEF
                     LEEEENVELVKYPALKSHPQYELCKTQMNGLGGGVVSFKLKDGINGLTRDQASRRLMN
                     SLELATIATSLGEEHTLVQMNGENLIRIAVGLESSNDIINDFKQAIEKLK"
     gene            complement(26775..27344)
                     /locus_tag="OE968_000403"
     CDS             complement(26775..27344)
                     /locus_tag="OE968_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HCP7217720.1"
                     /translation="MIIIYGYCRVSTKNQTDNNSLYQQQQEILNKYNDAKIIKETYTG
                     TTTNRPKFEKIISSLKKGDLLVATKLDRLARSTSEGIQLIEGLFAKEVSVHILNIGLL
                     ENTSMGKFFLTTLLAVAELERNMIIERTQLGKEFAKKKKDFKDGRPKKYSNQQIQYAL
                     GLLNSKPYREVVKMTGISKSTLIRAKKSI"
     gene            27547..27774
                     /locus_tag="OE968_000404"
     CDS             27547..27774
                     /locus_tag="OE968_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HCP7217721.1"
                     /translation="MNSLLKEAIDELKNIHCGEVFLLKELFKGYEWNRLEMNIRLKLG
                     KLFLYEVVTNPNLNVEVINKNSAYQQMYKKK"
     gene            complement(27993..28736)
                     /locus_tag="OE968_000405"
     CDS             complement(27993..28736)
                     /locus_tag="OE968_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HCP7217722.1"
                     /translation="MENYQSTNTCTYNILYVQFNEDFERSKYFSYDVKYPVIYNIRNQ
                     STYVNPVILNNINNAVRMTVNNFKNGLQEEEREYNNATSQNSLPKQSYWVSTSYAVTF
                     NKNYVLSMILNLMGFANNYGPKYNTLNNYNIDLTTGKELLLNDIFRDGVDYINIITDY
                     IKSQINENREMYYSNVELVIPEDQAFYLTDNGIIIYFGVDEIAPESFGIPKFELKFSD
                     FGNFINLRFYCISPDIYVQSRGRAKHFMG"
     gene            28904..29776
                     /locus_tag="OE968_000406"
     CDS             28904..29776
                     /locus_tag="OE968_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HCP7217723.1"
                     /translation="MLLLADKWKDYELIDMGNGEKLERWGSYVLRRPDPQVVWPMESE
                     WALWKNPHGHYHRSNKGGGQWEHKKRYPEQWTINYKNLKFHIKPTGFKHTGLFPEQAA
                     NWDWMIEKIKKANRPIKVLNLFAYTGGATVACASAGAEVCHVDAAKGMVNWAKENIEL
                     SGLKNQTVRFIVDDVVKFVEREIRRGKKYDAIIMDPPSYGRGPKGEVWQIEEKLYSFV
                     DLCMGVLSDNPLFFLINSYTTGFSPIVLENVLSTTIGKKTNTGDIYGGELGIPASRDG
                     KILPCGIFGRWEKK"
     gene            29776..30441
                     /locus_tag="OE968_000407"
     CDS             29776..30441
                     /locus_tag="OE968_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HCP7217724.1"
                     /translation="MIKVIYEDNHLLVVEKPVNILSQGDNTNDKDMVNLLKDYIKKKY
                     NKPGNVYIGLIHRLDRPVGGVMVFAKTSKAASRLSEQVRSKTFKKTYLAVVHGKIKSN
                     SDILKDFLYKNKKTNMVTVVKKSHKDAKEAELNYNVLDFKENLSLVQVNLKTGRSHQI
                     RVQFASRKHPLYGDQRYGKEINKIGQQISLWSNKIEICHPTTKEKMEFTCHPPDKYPW
                     NIF"
     gene            30462..31319
                     /locus_tag="OE968_000408"
     CDS             30462..31319
                     /locus_tag="OE968_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HCP7217725.1"
                     /translation="MSKKFSIGEMSKLHKISIQTLRYYDQIDLFKPVHVDQESNYRYY
                     SIDQFSQLDIIKYLKYLGMPLKEIKSKLDENNEEILKLLTNKINIVDEKIKELELIKK
                     VLSTKKETMEKGMKVDEVGKIVRKHIPRRSILSIEYEEGLSSEETMELSRRQIANILE
                     DNISVFYGGVSGLVSIDKFLKEDKVIYDNSFVTVERDLFDIKSQKHITEISSGDFICM
                     TYKGPYKENYTAFKKLVDYVEYKRIPIENYIYEIPIIDPLSTNNEEELLTEIQIQVKK
                     REIDLRCLV"
     gene            complement(31475..34021)
                     /locus_tag="OE968_000409"
     CDS             complement(31475..34021)
                     /locus_tag="OE968_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HCP7217726.1"
                     /translation="MNIFNKVALQGLKKNRTRTLVTIIGVVLSAAMITAVTTFGVSLM
                     NYMTNGAIIKYGDWHVQFLDVDSSFVQEQRVNDEVANTATFENIGYATLEGNRNPDKP
                     YLFIAGFSKEAFDTLPITLISGRLPENSREILVSSKVATDGGVKFAVGDTISLDVGKR
                     MSENEKLGQSDPYTAGSEVFVPQDKKTYTVVGICRKPVFEESSAPGYTLITKEDKQVK
                     TDSLSLFVTLKNPHQIRSYISSTKDHASIFNDNVLRFIGVSDNNLFNMFLYSVGGIVL
                     AIIMLGSIFLIYNSFNMSLNERTHQFGILSSVGATAKQLRNSVLFEGICIGAIGIPIG
                     VAIGIVSIGLVISVIAKNFANILYVNVPLTLTLSIPAIIVAAVVSMVTILISAYIPAR
                     KAANTPVMECIRQTNEVKIESKSVKTSKLTQRVYGLEGVLAMKNFKRNKKRYRSIVLS
                     LVLSIVLFISTSALVADLKQMSNQRSEVTDQDIIFSTQGMKDNEMLKLYDKLKTANGV
                     YEGLYQKLMTYSCVAKVSELTDDYLNYEGSHSMSEMLELPVDMQFLDDRTYLNIIKSL
                     GLPAEEYTGQNAKLIAVSMVTKDNNIIDIFNSSSMNVSLTPETNGKLEIPERQNVNIS
                     FVKVVPPDSPPGIRSSDVKKASFRVLAPYSAKDKFEIPGVSTGIESLSFQSKNPTQSV
                     AEMEQIIESEGVTNEYNLYNMYGMMDENRNYIFIANVFAYTFIIMISLISIANVFNTI
                     STNIKLRRRELAMLRSVGMSEHDFQKMMNFECAFYGMRALFFGLPIAVISSWLIHKVM
                     VTDDIDFVIPWFSIGISIFSVLFIVFITMLYTINKIKKENIIDALRDDMA"
     gene            complement(34021..34707)
                     /locus_tag="OE968_000410"
     CDS             complement(34021..34707)
                     /locus_tag="OE968_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCP7217727.1"
                     /translation="MAFLKIEDLCKVYGKNENKVTALDHVSLTIEKGEFTAIIGSSGS
                     GKSTLLHSIAGVDVPTSGKIYLEGQDVYGQSNEKLAIFRRRQVGLIYQFHNLIPTLNV
                     VENITLPILMDKRKVNQERLNDLLELLGLKERKTHLPNQLSGGQQQRVAIGRALMNAP
                     AVMLADEPTGSLDSKNGQEIIQLLKESHSKYHQTLIIVTHDENIALQADRIICISDGK
                     VVRDERKVNR"
     gene            complement(34790..35779)
                     /locus_tag="OE968_000411"
     CDS             complement(34790..35779)
                     /locus_tag="OE968_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HCP7217728.1"
                     /translation="MFRNREFRKFAILFLLITILTVALGFAISIMTGILSIVSATTFG
                     IAFFVFTKNRYKSIAQISEQINLVLHNANHLYIAESDEGELSILQSEITKMTLRIREQ
                     NYALKKEKEHLADSLADIAHQLRTPLTSVTLILSLLENTSDEDERKELIRETEELLIR
                     MDWLITSLLKLSRLDAGIVVFQKEQIDVNNLISSALHQLLIPMELHNITLHIDIPKGV
                     RILGDLNWLSEAIQNIFKNCMESVGDNGKIDIICEDNFLFTQLTIHDNGAGFKKEDLP
                     CLFNRFYRGKNSSTAGYGIGLALCKTIIMRQGGTITAQNHPQGGAIFVIRFPK"
     gene            complement(35766..36452)
                     /locus_tag="OE968_000412"
     CDS             complement(35766..36452)
                     /locus_tag="OE968_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCP7217729.1"
                     /translation="MKRIFLVEDDKAIAKNLILLLNSEGFIVTHVSTRSEALVEIAKN
                     KFDLALIDISLPDGNGFTICTEIKEKQDIPVIFLTASGDESSVVTGLNMGADDYITKP
                     FRPRELIARIRTALRKSGRFGSTFEICGLYVDTATGVVKKNGNEVFLSALEYRLLLVF
                     ISNPKSIITRVRLLDELWDAAGEFVNDNTLTVYIKRLREKIEDDPSSPQIILTVRGTG
                     YRLGGSYVSK"
     gene            complement(36952..40158)
                     /gene="carB"
                     /locus_tag="OE968_000413"
     CDS             complement(36952..40158)
                     /gene="carB"
                     /locus_tag="OE968_000413"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HCP7217730.1"
                     /translation="MPKLDSIKKTLVLGSGPIIIGQAAEFDYSGTQACQALKEEGIEV
                     VLVNSNPATIMTDKEIADKIYIEPLTIEFIEKIIEKEKPDSLLAGMGGQTGLNLAVEL
                     HDAGILDKYNVKVIGTSIESIKKGEDRDLFREVMKEINQPVIVSDIVTNLEAGLEFAN
                     KIGYPVVVRPAYTLGGTGGGIADTEEELREILSHGLQLSPVGQVLLEKSIKGWKEIEY
                     EVMRDGNGNCITVCNMENVDPVGVHTGDSIVVAPSQTLSDEEYQLLRKASIDIINAIE
                     VQGGCNVQIALNPHSLEYAIIEINPRVSRSSALASKATGYPIAKVAAKIALGYTLDEI
                     ENAVTKKTYACFEPTLDYVVVKIPKWPFDKFRHANRKLGTKMMATGEIMSIGSNFEAA
                     ILKGIRSLETGKYSLVHAPSEGRTLEELKARVVVPDDERLFDLAEMIRRGYKVEMISE
                     ITGVDKWFINKFKWIVEQEEKLKVLKIEDLDKEYLHELKKKGFSDKGISDLMKISPEK
                     LYELRSLYNIQPVYKMVDTCGGEFEALSPYYYSTYEQYDEVVVSDKRKVVVLGSGPIR
                     IGQGIEFDYCSVHCVKSLRKMGIETIIVNNNPETVSTDFDTSDKLYFEPLTEEEVLNI
                     IEKEKPEGVILQFGGQTAIKLAKFLHEKNIPILGTDFRDIDAAEDREKFDDLLERLDI
                     NRPKGKGVWTTNEGVEIAKELGYPVLVRPSYVLGGQGMEITYNEEKLIQYLDDAFDRD
                     HKNPVLIDKYLTGREIEVDAICDKEDILIPGIMEHLERAGVHSGDSTTMYPSQNISDE
                     IKEKIVEYTKKIALDLNVLGMVNIQFIEFQNELYIIEVNPRASRTVPYISKVSGVPIV
                     DLATKCMLGAKLKDLGYSTGVYKEPKLVSVKVPVFSMSKLSKVEVSLGPEMKSTGEVL
                     GVGENLEEALYKGFLAAGRHMSDERGVVLATVNNHDKDEFIEIAKDMKELGYTFVATE
                     GTAKSLRENGIEADIVNRIEEPRPNILDAIRNKQVDIVINTPTKGNDSTRDGFKMRRT
                     AIEFSTEIMTSLDTLKALVEVKKKHLNKDKLKVYNIAE"
     gene            complement(40351..41400)
                     /gene="carA"
                     /locus_tag="OE968_000414"
     CDS             complement(40351..41400)
                     /gene="carA"
                     /locus_tag="OE968_000414"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002845470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HCP7217731.1"
                     /translation="MKARLILEDGTVFIGKAFGYLEESVGEVVFNTSMIGYGEVLTDP
                     SYYGQIVTMTYPLVGNYGINLSSAESEKVQVKGFIVREKSDSPSNFRCEIDIDQYLKQ
                     NKVIGLEGIDTRALTKILRNNGTMKGIITLEDSKLEDVKHKLDKFSNTEAVRTVTRKE
                     VEHIKGNGPKVAVMDFGVKRNILRSFIARGCDITIFPATTSPEDVLSINPDLIFLSNG
                     PGDPEDLEDVIENIKALIGKKPIVGICLGHQLLALALGGKTAKLKFGHRGGNHPVKDL
                     EEGKVFITSQNHGYYVSEVPEQMKVTHINLNDNTVEGMRHEKLDVYSVQYHPEACPGP
                     KDNDYIFDKFLELVK"
     gene            complement(41657..44863)
                     /gene="carB"
                     /locus_tag="OE968_000415"
     CDS             complement(41657..44863)
                     /gene="carB"
                     /locus_tag="OE968_000415"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HCP7217732.1"
                     /translation="MPKLDSIKKTLVLGSGPIIIGQAAEFDYSGTQACQSLKEEGIEV
                     VLINSNPATIMTDKEVADKIYIEPLTIEFIEKIIEKERPDSLLAGMGGQTGLNLAVEL
                     YEKGILDKYGVKIIGTSVESIKKGEDRDIFREVMKEINQPVIVSDIVTDLQAGLDYAL
                     TIGYPVVVRPAYTLGGTGGGIADNEEELREILSHGLQLSPVGQVLIEKSIKGWKEIEY
                     EVIRDSKGNCIVVCNMENIDPVGVHTGDSIVVAPTQTLSNKECAMLKKASLDILNAVE
                     VQGGCNVQFALNPHSFEYAVIEINPRVSRSSALASKATGYPIAKVSSKIALGYTLDEI
                     ENAVTKKTYACFEPTIDYVVAKIPKWPFDKFKKANRKLGTKMMATGEIMSIGSNFEAA
                     ILKGIRSLETGKYSLVHTPSEERSIEELKKRVVVPDDERLFDLAEMIRRGYKVEMIEQ
                     ITGIDKWFINKFKWIVEQEEKLKVMKIEDLTKDYLLELKKKGFSDKGISDLMKISPEK
                     LYELRSLYNIKPAYKMVDTCAGEIDAISPYYYSTYEQYDEVVVSDKKKVIVLGSGPIR
                     IGQGIEFDYCSVHCVKSLRKMDIETIIINNNPETVSTDFDTSDKLYFEPLTEEEVLSI
                     IEKEKPEGVILQFGGQTAIKLAKFLHEKNIPILGTDFDDIDAAEDREKFDDLLERLDI
                     NRPKGKGVWSLNEGIEVANELGYPVLVRPSYVLGGQGMEITYNEEKLSQYLQDAFDRD
                     HKNPVLIDKYLTGREIEVDAICDKEDILIPGIMEHLERAGVHSGDSTTMYPSQNISDE
                     IKEKIVEYTKKIALDLNVLGMVNIQFIEFQNELYIIEVNPRASRTVPYISKVSGVPIV
                     DLATKCMLGAKLKDLGYGTGVYKEPKLVSVKVPVFSMSKLSKVEVSLGPEMKSTGEVL
                     GVGENLEEALYKGFLAAGRHMSDERGVVLATVNNHDKDEFIEIAKDMKELGYTFVATE
                     GTANSLRENGIEADIVNRVEESRPNILDAIRNKQVDIVINTPTKGNDSTRDGFKIRRT
                     AIEFSTEIMTSLDTLKALVEVKKKHLNKDELKVYNIAE"
     gene            complement(44916..45959)
                     /gene="carA"
                     /locus_tag="OE968_000416"
     CDS             complement(44916..45959)
                     /gene="carA"
                     /locus_tag="OE968_000416"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HCP7217733.1"
                     /translation="MKGKLILEDGTVFEGKAFGYLKEAIGEVVFNTSMAGYGELLTDA
                     TYYGQIVTMTYPLIGNYGINLEDVESNKVQVKGLIVREKSDNPNNFRCEMDIDTYLKQ
                     NKVIGLEGIDTRALTKIIRNNGTKRGIITLENVSLQDVQSKLEEHCNKDSVKNVTRKE
                     IENIKGTGAKVVVIDFGVKNSVLESLKACNCDITIVPAMTTVEEILNINPDLILLSNG
                     PGNPEDINDIVENIKKLIGKKPLTGIGLGHQILALALGGKTSKLVFGHRGGNHPVKCL
                     ETGKVFITSQNHGYNVSEMPENTEVTHINLNDNTIEGMRHKELPIYSVQYIPEYTTKE
                     DLDCIFNKFLALI"
     gene            complement(45985..46701)
                     /gene="pyrF"
                     /locus_tag="OE968_000417"
     CDS             complement(45985..46701)
                     /gene="pyrF"
                     /locus_tag="OE968_000417"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HCP7217734.1"
                     /translation="MINGKEKLIVAIDTDEFDKAKELIDRLEDSVDIFKVGLEQYVAT
                     KGKTIDYLKEKGKKIFLDLKFHDIPNTMKSAVKAAVRDNVWLMTIHVSDMEGMRQCAL
                     IAREEAERLNIEKPLVVGVTVLTSLSNQDLQDIGCNMTTEELAIKRAKLAKESGIDGV
                     VCSAQEVDKIVEACGTDFITVCPGIRPKSAEVGDQKRVVTPSDAIKKGAHYLVVGRPI
                     TKAENPRESAINIVREIENA"
     gene            complement(47077..47712)
                     /locus_tag="OE968_000418"
     CDS             complement(47077..47712)
                     /locus_tag="OE968_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1847 domain-containing protein"
                     /protein_id="HCP7217735.1"
                     /translation="MYKCGKCNLRGCSNGNMDKLMKICPTREIELQQKAKQLYEEEEN
                     RKIAYNAGLVEAEGYCQYTRLKEIIEFAKKCGYKKIGIAFCIGLKREMQTVQKIFEHH
                     GFEVFSVICKNGAMPKSTIGLEASQTISKCSDEVMCNPIGQALFLNEAKVDLNVILGL
                     CVGHDTLAMKYMEAPITTLVVKDRVTGHNPVAAIYNAESYFEKKLFDKDEE"
     gene            complement(47736..48650)
                     /locus_tag="OE968_000419"
     CDS             complement(47736..48650)
                     /locus_tag="OE968_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7217736.1"
                     /translation="MELYEAIFYRKSVRNFSSKKIKKPLMEEIKRSCKNLEYLNEDLN
                     IKAHVVDRGHIIHFLMGKECKVKAPHYIVVTSDKGEDYLQNIGFATEGVVLRLTTLGI
                     ATCWLEGNLKREDILEFVDIGNKNFEEDEEDDLDYLAGIKTEEDDENKIENPYIIIAF
                     GYPAKNEELFRTRYARPDRKPVKDMINKINRNRKWKDILELTRRAPSVKNSQPWYFHK
                     DERGLHLFEKRPKKHCEDMNKVSLGVALRHFDIACIKNKIDVSYEKLPIRNKIGKSYF
                     ITVVEHVKPEEETQEENVTLEKEESQDE"
     gene            49251..50480
                     /locus_tag="OE968_000420"
     CDS             49251..50480
                     /locus_tag="OE968_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HCP7217737.1"
                     /translation="MNLNRNLEKYAELAIKVGVNIQPGQILLIKSPIECADFARNALK
                     EAYKCGAKNVYIEWSDEESTLIKYLYAPDEAFHEFPKWTAEQYVDIAKEGGAFLSVYA
                     QNPDLLKDVDPERVANFQKASGKALKEWRSYTLTDKCKWNIVSVPTKDWAKKVFPNLS
                     EDKAIEKLWDAIFKCSRVDGQDPIKAWEEHNENLKSKMDFLNKNNFKTLKYKSSKTDL
                     TLDLPKGHVWLSGASKDPNGISFNPNIPTEEIFGMPHKFKVNGTVYSTKPLVYGGNII
                     DNFFLTFKDGKIIDFSAEKGLDTLEKLIETDEGSHYLGEVALVPYNSPISNTDIIFYN
                     TLYDENASCHFAIGSAYKTCLEGGNNLKDEELDEHGVNDSLTHVDFMIGSADMDIIGE
                     TYDGKQIQIFKNGNWAF"
     gene            complement(50685..53066)
                     /locus_tag="OE968_000421"
     CDS             complement(50685..53066)
                     /locus_tag="OE968_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homocysteine S-methyltransferase family protein"
                     /protein_id="HCP7217738.1"
                     /translation="MEIRQYLKNNILIFDGAMGTMLQQKGLKLGENPEVFGLQNPDKL
                     IEIHTAYLEAGSNVILTNTFGCNELKLDSKYTVEEVIDNAVLVARKAIENVDNTKPRY
                     VALDIGPIGEMLEPMGTLSFDKAYEIFKRQVLQGVKSGVDVIVIETMMDLYEAKVAVL
                     AAKENSDLPIFCTMTFDEGGRSFTGCMPECMVATIEGLGVDAIGVNCSLGPKQLLPIV
                     EKIASRATVPVMVQANAGLPNIVDGEAIYDVDAKEFFEGVKKFVEVGATIIGGCCGTN
                     PSFIKEISENINSVTKGCIEKIDKCVVCSPSKFVEVQSPTVVGERLNPTGRKSLQEAL
                     KNENVDYAINLGLEQVNAGAQILGVNVGLPEIDEKKLMPKLIREIQAVVDTPLQVDSS
                     NVEALEQGLRYYNGRTIVNSVNGKEESLESILPIVKKYGSCVVGLTLDEKGIPKKAEE
                     RFEIAKRIVNRAVSYGIKPKDIFIDCLSLTVSAQQEEAIETIKAITMVKTLGVKTILG
                     VSNISFGLPNRKALNASFLTLALGAGLDLAIINPNEYSMMEAINSFKILNNTDKGCIN
                     YINQYSNINNSKKSDSSTKIDKDLPLDILVERGLKDEAKNVTLNLLKEKDENYILDEI
                     LIPALDKVGKRYDSGDIFLPQLIQSAETVKVSLNTIKETLLSKSSNNVSKGKIIVATV
                     KGDIHDIGKNIVKIMLENYGYEVIDLGKDVPIEEVVEVAKKRNIKLVGLSALMTTTVQ
                     SMKDTIQALRDNEINAKVFVGGAVLTEEYAEEMGADYYSKDAKSAVEIAKLNF"
     gene            complement(53038..53763)
                     /locus_tag="OE968_000422"
     CDS             complement(53038..53763)
                     /locus_tag="OE968_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Vitamin B12 dependent methionine synthase,
                     activation domain protein"
                     /protein_id="HCP7217739.1"
                     /translation="MENNLIGREDISINQSEVLRYLQYRGQEIDKDLKYTIDECVAIT
                     KNKINPRYLSRIYPIRINKDNVVELEGTNLTLESKYVYELLKECNECVIMAATIGIDI
                     EKEIRRHSYSNLTKGLIIDSCGTTAIEEVCDIVQNNLEKVFLKQDKFITMRYSPGYGD
                     LPIEKNIDILNVLNAQKQIGLTITSNGIMIPRKSVVAIIGISNTRINKSKKEKSCENC
                     KNYRNCTYRKGANSCGNKTISEK"
     gene            complement(53753..54208)
                     /locus_tag="OE968_000423"
     CDS             complement(53753..54208)
                     /locus_tag="OE968_000423"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HCP7217740.1"
                     /translation="MEKVESFKLDHTKVKAPFVRKCSVLDGVKGDKVTKFDLRFLQPN
                     VESFGTAAMHGLEHLLATYLRDTLDGVIDLSPMGCRTGFYLILWGDVDAKTVKIGLEE
                     ALKKVLESDKMPAATAIECGNYRDLSLFGAKEYAKDVLDKGFSLNIYGE"
     gene            complement(54490..55671)
                     /locus_tag="OE968_000424"
     CDS             complement(54490..55671)
                     /locus_tag="OE968_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HCP7217741.1"
                     /translation="MKNKSLLNHMFRPILDLIISCALTSMLILTSMYIIKSLYVNSDM
                     SVVNQLVYQARDFRSLIGYDLFYPFLFTITSLAIYSIISYKRNKQIVDFIRKTNRKNQ
                     KLEIIKSAVNLMDEGNLEKSIDIEYDLDILKDKEKDDIDELAHKINNIVHQLRNITIE
                     ERQAQQTKTDLITNVSHDLRTPLTSIMGYLGVIEEGKYKDEVQMMYYVDIAYEKSKNL
                     NVLINDLFELTKMQNNTIKLNKIEINLVELLSQVVSQFEIYFKQEFMVSRINFNEEKL
                     IVKADPNKLVRAFENLITNAVKYGKDGHYVDIVTEKKEDMAVVKVINYGEPIPVLDLP
                     NIFDRFYRVEKSRNRNVGGSGLGLAITKNIVNLHDGEITVSSDKYQTVFEVQLPIIQS
                     A"
     gene            complement(55661..56353)
                     /locus_tag="OE968_000425"
     CDS             complement(55661..56353)
                     /locus_tag="OE968_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011948339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCP7217742.1"
                     /translation="MNNTVLVVDDEKEIRDLIEIYLLNSGYNVIKAEDGKEALDILKK
                     ENIHLMILDIMMPKMDGIEVCRKVRESLNIPILMLSAKSEDMDKIQGIMTGADDYLTK
                     PFNPLELTVRVKSLIRRAYYFSGANNEDKDVIKVGVVIIDKEKHSVTVAGNEIILTSR
                     EFDILYLLANNKGRVYSTEEIFEKVWKEKYYQSNNTVMVHMSRIRDKIEKYTDGEKII
                     HTVWGVGYKIEK"
     gene            complement(56487..57203)
                     /locus_tag="OE968_000426"
     CDS             complement(56487..57203)
                     /locus_tag="OE968_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HCP7217743.1"
                     /translation="MKKFKLIGAIILVVFISVFISKDRLLKKDKDPIVAAQHDSEQDV
                     EANSQNKNHSNSISNILLVNKTNGISKNYTPENITKVNIPFVEEATEEEKQMAGEPAK
                     AVEDLVKQANSEGIQFLGSSAYRSYDTQLDTYTRRVKSQGREKADAYVAKPGYSEHQT
                     GLCIDLTNPERWFVGSTKEAKWLAENAHKFGFIIRYPEGKEDITGTAYEPWHIRYVGK
                     DAAEEIYSKGLTLEEYLQNK"
     gene            57328..58062
                     /locus_tag="OE968_000427"
     CDS             57328..58062
                     /locus_tag="OE968_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiocytidine(32) synthetase TtcA"
                     /protein_id="HCP7217744.1"
                     /translation="MSIQKLLSKARKAIQDFDMIQENDKIAVGLSGGKDSLTLLHILK
                     SYQRFSPQNFELIAITLNTGGVDNSPLDKLCKEINVPFYEFQTDIKEIVFDIRQEKNP
                     CALCANLRRGALNDNAKKLGCNKVALGHHKDDAIETFLMSMFYEGRVNCFSPKTYLDR
                     QDLTVIRPMVYIEEYMTKKISKDSNYPIITNPCPANGHTRREYIKNLIANLNKEMPDF
                     KRNVFGALNNSEKLFIWDKEKIKNFK"
     gene            complement(58347..59198)
                     /locus_tag="OE968_000428"
     CDS             complement(58347..59198)
                     /locus_tag="OE968_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HCP7217745.1"
                     /translation="MNSKIKYFLKFFILIFILIFIYSVAIEPSLLIVKKYNISENGTL
                     IKSDTIESKSERIKVVQISDTQIGSFYSTKNLKKVANKINTLNPDIIVFTGDLIDYSN
                     KNPSVDEITTILSSMNARLGKFSVFGNHDYMYKLPRYYRQIMKNSNFNLLVNENKKIK
                     LKDDKYINILGVDEILNGNPNIKYLESQIDNKNFNLLLAHEPDLVDMLSKDTMNLVLS
                     GHSHGGQIRLPIKGALVTPPYGRKYTKGFYDINGNHLYVSSGLGSTKLPFRFFNIPEI
                     IEFNIII"
     gene            complement(59224..60162)
                     /locus_tag="OE968_000429"
     CDS             complement(59224..60162)
                     /locus_tag="OE968_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HCP7217746.1"
                     /translation="MKSILIMGGSDFIGSALAKRLIKCGYQIDILTNGKKEIDYNGFK
                     EHLICDRKVRKDMENIITGRKYDYIYDMTAYTKEDVSNLIDFISMDNLKKYIVLSAGA
                     VYKDSGRNIKEENEKGENENWGKYGLNKKEAEDFIINSPIPYIIIRPTYIYGENNNLY
                     REYYFFEKIEKNEKIPVPKGKQVSNQFIYIGDLVKVLESIMKNPHVREAYNVTNPQLI
                     SWDDLIYTCGEIIGKEPIIKYVDMEKVEFRERTYFPFRNIDFNLDINKLIEHGLYIPN
                     VLLKEGLTATYKWFSANKPKMHDRKMNKVESVMQIV"
     gene            complement(60265..60915)
                     /locus_tag="OE968_000430"
     CDS             complement(60265..60915)
                     /locus_tag="OE968_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HCP7217747.1"
                     /translation="MKKNYEIVLFDLDGTLTDPKEGITKSIQYSLNSFGIKEDLENLD
                     QFIGPPLHDTFKEYYKFEDKKTKEAVEKYREYFADKGIFENKIYENIKEILEMLYKNG
                     KILLVATSKPTVFAETILRYFDIDRYFKYIAGSNLDGTRVNKNEVIQYVLDLCNVKDK
                     DKVIMVGDRKYDIIGAKKIGIDSIGVLYGYGSFEELSESEPTYIVENVESIKDILL"
     gene            complement(61065..61253)
                     /locus_tag="OE968_000431"
     CDS             complement(61065..61253)
                     /locus_tag="OE968_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HCP7217748.1"
                     /translation="MKAFVDKDVCVACGACIGTCPDVFSMSDEGHSVAIEGEIPADLQ
                     DLCKEAEEGCPVSAITVK"
     gene            complement(61360..62544)
                     /locus_tag="OE968_000432"
     CDS             complement(61360..62544)
                     /locus_tag="OE968_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HCP7217749.1"
                     /translation="MKNLLIRNGTIISPTDGIKFEKRDILVLHGKIYAIGLNLKEKIR
                     KEKLLTNKEFEIINADNMYISPGFIDVHTHCYKRKLPTGMDSDSIGIEKGSTVIFDAG
                     TAGPLNYYDFKKKYMDECKTEVYSFLNVTNEGLNILNESTSLDVINFDKVESVVEKNI
                     EKIKGIKVKASKFQSNESGIDIIKKSKQVAKKLNLPLVVYIGEYPSYIDEVMNILGKG
                     DVVTPVYGNSTNGILKESGTLRKSVINAKNRGVLFDVCHGLNQFDFKVFKKAIKQGLE
                     PDLISTDMHIKNMKDVNYSLLSVINKIMELGISLEKCIEKVTEYPTKIFDLHGNKGRI
                     KIGGEGDFTIFTMEECNDIIKDYNNNELVLNKKLRLQYTVKSWMKSSEVYRHGYENTI
                     IN"
     gene            complement(62686..63603)
                     /locus_tag="OE968_000433"
     CDS             complement(62686..63603)
                     /locus_tag="OE968_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SufD family Fe-S cluster assembly protein"
                     /protein_id="HCP7217750.1"
                     /translation="MNKIDLNLLEKVAELRGTPLGAYNIRKNGQGVERHSTENVTIIP
                     KTDKPGIDIIVKPNTKGENVHIPVIVTETGVQDMVYNDFEIGENADVVIIAGCGIHNC
                     GCDDSEHNGIHRFFLRKGARLKYVEKHYGEGDGEGKRILNPVTIVNMDEDSYCEMETI
                     QIKGVDSTKREMDANLGKGAKIVVFEKLLTHGNQVAESNMKVILEGENSSAQVVSRTV
                     GQDNSKQKFNPCVIGDSLCSAHVQCDSIIMGNSQISAIPEIAANHPDALLVHEAAIGK
                     IAGDQILKMMTLGLTEEEAEQQILNCFLK"
BASE COUNT        19947 a        11740 c         6948 g        25007 t
ORIGIN      
        1 tttcgtcaat actttttttg ttttttattt taaaaaaggt tataactttt gtttttttta
       61 ataaatataa ttaaaactaa tagatataac ccttgatatt acaaacaata catgcatata
      121 taattttacc tattttgcaa ttttattttc ataagaatat gaattagctc tcactctatc
      181 tgcccaaaca tttatactct taactttatt aacattagtt gtaccctcaa aaatatccat
      241 tgcatcctta caaaaatata tcataacatc aagaaccaaa aatccaacac aaaataaaca
      301 taaaaaatta attacttgaa acatcagaca ttcccccaat aattttttat atatagtatt
      361 ctcataaatt attcttttta ccttctcata aattattcta aatattttca taataaatta
      421 ctttcaatca tattttctaa atataaagtc tcaatcaaca aaaactaata tcaatttcta
      481 acgtttgttg gtaatttata aattaaatat ctaaaagaat ctttgaagca tataaaaagc
      541 attctacact gacattttaa ataaaattta gctatttatt gataatttaa tagctaaact
      601 ttatttaaaa cttagtagaa tgctaatatt tcttagtttt cttcttcttt atttggattg
      661 ttatcaatag gtttcatagt cgggaataat aatacatctc ttatagatgg agagttagtt
      721 aataacataa ttactctatc tatacctatt cctagtcctc ctgtaggagg tagacctacc
      781 tctaatgctt ttaagaaatc ttcatccatt tcaaaagctt catcatcacc taattctctt
      841 tttcttaatt ggtctataaa tcttcctttt tggtcaatag ggtcattaag ttcagaaaat
      901 gcattagcta actcccactt attagcaaat gcctcaaatc tatcagttct tcttgggtct
      961 tcaacatttc tcttagataa tggagatact tcaactggat gatgagttat aaatgttggt
     1021 tggattaatt tatcttctcc aaattcttca aagaaagcat ttattacttc tcctcttctc
     1081 attccaggtt ttatctctat acctttttct ctagcaactt ctagtgcctc ttcatctgta
     1141 tttatagtag aaaaatctac accagaatat tctttaacac aatcttccat actcattctt
     1201 ttccaaggtg gtgtaaagtt tatttctgtt ccttgatagt taactatcat acttcctgta
     1261 gcaacttcag ccatatgtgc aataacattt tctgttattt ccatcatatc agtatagtct
     1321 gcatatgctt gatataattc tattgcagta tattcaggat tatgttttaa atccatacct
     1381 tcatttctaa acattcttcc catttcataa actttatcaa atccaccaac aataagtctt
     1441 tttaaataca attcattcgc tattcttaaa tacattggta tatgtaaagt attatgatta
     1501 gttataaatg gtctagcatt tgccccacct gctatagtat ttaatattgg agtctcaact
     1561 tctaaaaatc ctctatcatc taagtatgct cttaatgctt ttaatgcttt tgttctaatt
     1621 aaaaaagcat tttttacttc tggatttact attaagtcaa catatctttg tctatatctt
     1681 agttcttggt cttttaatcc atgatatttt tctggtaaaa cttgtaaaga tttacatagt
     1741 aatactacag atttagcctt tacagatatt tcaccttttt tagttttaaa gatttctcct
     1801 tcaattccaa ctatatctcc aatatcatat gttgaaaata cactatattc ttcctctcct
     1861 atagcatcta gtcttacata agattggatt cttccctctt ggtcttgaat atctataaag
     1921 ccagctttcc cttgtattct cttgctcatt atacgtcctg ctatttttgt agttttaccc
     1981 tcaagagaat caaagttatc ttttatatcc atagaataat gagttctatc atatctactt
     2041 tctttaaaag gatctctacc tgattcttgt aattttttta gtttatctct tcttacttga
     2101 agtacttcac taaggtcttc ttgaatttgc gcttcttcat tgctttgttg attatttttc
     2161 atttttttcc tccaaattat cttcttattt ctaatatttc aaacttagca actccatcag
     2221 gaacttgcac ttccacaact tctttcgcag ctctacctaa aagtgctttc cctacaggag
     2281 attcgtttga tattttacca tcatatgggt ctgcttctgt cgaaccaact atagtatatt
     2341 caacctcttc atcaaattct aaatccttaa ctttaactat tgatcctatt gtaacaacat
     2401 taaggtctat tttgctttca tctatgataa cagcttttct aaccatattt tctaatttta
     2461 aaattctttc ttcaacttgt gcttgttcct ttttagcttc atcatactca gcattttcag
     2521 ataaatcacc aaaagatata gcaactttta ttctctctgc aacttctttt ctctttacaa
     2581 cctttaagtt ttctaattct tcttctaatt tatcatatcc ctcttgtgtc aataaaaact
     2641 ctttattttc ttccattata aatacaactc cttcacaaat ttcttaggaa ttttcctaat
     2701 tatattttaa aaattttata atcttttttt aatttatgcg ctatattata agtcactatt
     2761 atttttatgt caaggagtct tccatatagt actccaattt cgacacaact tcttgatagt
     2821 cttctatttt gttaatttca tcccttaatt ttgcagagtt tctaagtcct tttaaatacc
     2881 aagcgatgtg ttttctcatt tcccttacag ctacatactc tccatgttct tctactgcaa
     2941 gttttaaatg cttaatggca gtacttattt tttcgttaag agttggctct ggcaaaatct
     3001 cgcctgtatt catataatgg tttattcttt taaatatcca agggttacct tgagcacccc
     3061 tacctatcat tatagcatca caaccagttt tgtctaacat atttattgaa tcttctattg
     3121 taaatacatc accatttcct ataacaggta tactcaaatt tttcttaatc tctgcaatta
     3181 tatcccagtc tgctttgcct gtataaaact gttctctagt tcttccatgt attgctaaag
     3241 cacttattcc acaatcctct gctatctttg ctatttcaac agcatttaca ctattatcat
     3301 cccagccttt tcgaatcttt aaagtcactg gcttttttga gttcttcact actgccctca
     3361 atacctcttc tgcaagctta ggatttttca taagtgctga accatctcca tttttaacta
     3421 cttttggagc tggacacccc atatttatat cgagaatctc atttgaataa tcattcatta
     3481 tctctgctgc tcttcccata aactctggtt ctgaaccgaa tatctgaact gctacaggat
     3541 gttcttcctc ttctatctta agcatttttt tagtattttc atcatcatag caaagtgcct
     3601 taccatttat catttctgta tataaaagcc cacatccttg ttctttacaa attaatctaa
     3661 atggaaggtc tgttacacct gccataggtg atagaaaaac tttatttttc aattctaaat
     3721 ttcctatttt cattgttttt ctcctatttt tgcctttatt ttgtgattta actttaaatt
     3781 cttatttcct cattataata taccacatat agctagaaat ctatcataaa aagggaattg
     3841 gatatataac ccaattccct gtatattaat tattcttggt ttttttcata tattattctc
     3901 aatccttcta gtgttaaaaa accatctaca taatctatac ttttcgtctc tgaagcaatc
     3961 agtttagcta acccacctgt agctataacc ttaacatcat cacaattcaa ttctttcttc
     4021 atcatactta ttattttgtc aactaaacca acatatccat aaattattcc agattgcatg
     4081 gctgatacag tactcttaca aatagtcata cctggcttag ctaattctac tctaggtaat
     4141 ttagacgcac tttgaaataa cgcctcacta gatattttta ttcctggtgc tattgttcca
     4201 cccaaatatt cacctttttc agagatagca caaaatgtag ttgctgttcc aaaatcaaca
     4261 agtatacttg gtgctccata cttttctatc cctgctacag cattaactat tctatctgcc
     4321 ccaacttgtt ttggattatc atattttata tttagacctg tttttatgcc tggacctact
     4381 attaatggct gttttttaca gtactttata caaaagtttt caagagaatg cataacattc
     4441 ggaactacag atgatattat aacatcatca atatcactta tattcacatt atcataatca
     4501 aataggttac ttattaggat tccatattca tcagacgttt tttctctatc tgttttaatt
     4561 ctccagtaat taactaattt gtcaccttta tatataccta aaaccatatt agtatttcca
     4621 acatcaaata ctagaagcat atgtcattaa ccttctttct attttttgct tttcttaagt
     4681 acagtggcaa cagcagctac tactaaagcc cctactattg cttctggcac cccatttgct
     4741 gcggcaagag ccattattac ttttcctgct gaaccacttt tacccattgc atgaagatac
     4801 ttgtcagcat ataagacata tatcattcct aaaactccag ctgtatttaa cagagaacct
     4861 attgcccctg taattaaacc tgatatgtat accttatttg tagccttaat tattaactga
     4921 tatacataat aagctaatac acctatcata actcttggta atattgaaac taatggattt
     4981 ataaaaacaa aagatgttac tgttgggttt gttatagcat ttaagagact tgatatccca
     5041 aatataaatc ctattgctgc cccaactatt ggtccttcca taatagctcc aataataact
     5101 ggtatgtgca ttatagttgc ttttgtaggt ccaactggaa taaatcccaa tggagtcata
     5161 gatagcataa tagaaatagc tgatagtact cctattatag tcatctttct tacatttact
     5221 tttcttactg atgcacttgt gttcatcata aaaaatacac ctccgttcca gctcattaag
     5281 atgccggact acttaatttt ttaatttttt tcgttttttt cttataacta tgagtcaagc
     5341 taccattgta ggatgcccgc tctaacaaga ataattttat caagatgagt tgccattgtc
     5401 aacaatttga caagaaaaat atgctaattt catcatattt ctcgtttttt tactatatct
     5461 ttatatgcca ttatattttc tacactatcc gcttttttta ctgcatttat tatacttttt
     5521 tccacaacct ctacagccaa tgaacctact aatgttatat ctgcttctat ttctcctgtt
     5581 gatattgtga atattgtatc tccatcatga ggtgtatgga taggaaaaat agacttagca
     5641 tatccatcat gtcccatttg agatatcttt ttacatccag ctttggttaa cttagcattt
     5701 gttgcaatta tcccaattgt agtattatct acactaaatc cacctttact ttcaccttgt
     5761 ttcattaatt tatatgtatc aattgtttct gtctttttat catttaaagc accagctata
     5821 accttaccat tttcataaac atctccaaga gcatttacag caattaatgc agatacaatt
     5881 agaccattat ctaattttat agaatagcta cctattccgc ctttcatagc atattcctga
     5941 cctcttatct ttccaacagt ggctccacaa cctgctccat aatttccttg atttaaaata
     6001 tcagtatttg caacttcaca agctctataa cccatcttta aatctggtct acatttaaag
     6061 ctccctactc ctaaatcaaa taaaactgct cctacaacta taggcacttt acctacacct
     6121 acatcaaatc caattccttt ttcttctaag tatctactta caccacaagt ggattcaaga
     6181 ccatatgcag aacctccagc caaaactact gcatgaactt tttgaaccat atttacaggg
     6241 tctaataaat cggtttctct agtacctgga gcagagcccc ttacatcaac accgcaagta
     6301 gctccttctt cacatattac tactgtgcac ccagtaagac catttctatc ctcaacctgc
     6361 ccaaccttta agccttctat atccaaaata ttattataca tatccttttt ctcctcttat
     6421 agaaacttca cctgaaataa tttcttttat acttccatca cttctttgaa ctaataaatt
     6481 tccctcttca tttatgtcta aacatttcac tagttctcta ttatctcctt ttaatacata
     6541 tatattttta tctataattg cagaataatc tctacatatt tttaaggttt tttctttgga
     6601 attatttaca gtataatcta aatataattt ttcaaattca gtcaatacat tcctaacaat
     6661 atctactctg gataacatat acccttcttt atacaatgat gtggctttgt cagctatttc
     6721 ttgttcaaaa tccattattt taacatttat tccaattcca agaacaacat aatttgttct
     6781 ttcaatttca gcagataact ctgttaatat accacatatt ttttttccat ttaaaataac
     6841 atcatttggc cattttatta atgtatttgc tcctagattg tttaaagctt tcgttacact
     6901 tgctcctgct attaaagtta taaatggggc tttgaatggt tccatatctg gttttaatat
     6961 aatactcatc cagattcctt catgaggttt tgaatcccat cttcttccca atcgtccttt
     7021 ccccatatct tgatgttcac ttaaaatcac agtcccatct acactattta tagctatcct
     7081 tttagcatgt tcatttgttg aatctatagt gtcaagatgt tcaatatttt ttccaataaa
     7141 ctctgtatct aatttatagt aaatattctg tgggcttaat aaatcagttg gattttccgc
     7201 taatcgatac ccttttttat ttacagattc tatattatat ccctcttctt ttaaggcttt
     7261 catatgtttc catatagctg cacgtgacac ccctaattgt tttgataatt cttctcctga
     7321 aataaattca gatttattat ttaatataat ctctattatt ttatctctca tatttcacct
     7381 ctaatatgac ataatttcat gacttatttt cttctaataa ataattatac attattaata
     7441 tacttttaat actattaatt ttaaatttcc tttttaatta ttataatggt tgttttatat
     7501 tttatattga tgatttatat aattttacat tttatttaaa taattttaaa ataataaaaa
     7561 aactgaaagt atcaattaaa ttaatacatg caaatataat ttgcttatta atttaatatt
     7621 atactttcag ttttagtatt taatccacat cagataataa tcttaaaatg accaaggtct
     7681 taaaactatt tatctttatc agatttatct tctaaatttt tatttatatc aataacattg
     7741 tttctttctt cttcatcttt ttctaatttt atagttaatt gttcttcaac ttctttagaa
     7801 gaattttcct ctgtaactgc attttcaatt tcattcagag gtaactcttt attaaatgct
     7861 tttacaaatt gttctgcatc taaagtttca tatataagta aagcttgtgc tacatactct
     7921 aatctatcca tattttcttg taatatactt cttgtcttat catatgcacc atcaactata
     7981 cgctttgttt cttggtctat ctcaaaagca acttcttcag aataatttct cttacttgaa
     8041 aaactattac ctaggaatac ttcatcatca ctgtcaaatg acattggacc aagtttagaa
     8101 ctcattccat actttgttac catacttctt gcagtagctg taactctttc taagtcattt
     8161 gaagcacctg tagatacatc cttaagtact agctcttctg ctactctacc accaagtaaa
     8221 actacaatat tttctttcat ttcatttttt gtagcataga acttatcttc aacaggaagt
     8281 tgcattgtaa accctccagc tcttcctctt ggaactattg taacttgatg aacaggactt
     8341 acttcttcaa gtacatgggc acaaactgca tgccctcctt catggtatgc tgtaagtctt
     8401 ctttctttct cacttattac tttcgatttt ttagccacac ctgctataac ctttgttata
     8461 gcttcttcta tagtttccat cttaattttc ttttctcttt ttctagctgt taatattgca
     8521 gcctcattca ttaagttctc tatatcagca ggagtaaatc ctggtgttct tctagccaag
     8581 acatccattt ttacatcatc acttaatggt ttatttcttg agtgaacttt aaatatagcc
     8641 tctctacctt ttacatctgg tgtaccaaca acaacttgtc tgtcaaatct tcctggtcta
     8701 agtaaagctg ggtcaagtat atctggtcta tttgtagctg ccatgattat tataccttga
     8761 tttaccccaa atccatccat ttcaactaga agttgattaa gagtttgctc tctttcatca
     8821 tgacctccac caagacctgc acctcttttt ctaccaactg catcaatttc atctatgaat
     8881 atgatagctg gagcactttt cttagcctgt tcaaataaat ctcttactct tgaagcacca
     8941 accccaacaa acatctcaac gaaatcagaa ccacttatac tgaaaaaggg aactcctgct
     9001 tctcctgcaa ctgctcttga tagatatgtt ttaccagttc caggaggtcc taccataagc
     9061 attccttttg gtattcttgc acccaattca atatatttct taggattctt taagaaatct
     9121 actacctcct gcaaatcttc tttttcctca tctagtccag ctacatcttt aaatgtaact
     9181 ctagtttttt catcatcttt atgaacctta gcttttgatt tgccaaaact cataaccttt
     9241 ccgcctccac cttgagactg attcataaac acgaaccaaa taatcaccat gaagaatatt
     9301 aacagtaatg taggcaacat ttcgacaaac caaggtgtag atggcttagc ttcaccacca
     9361 aaagttagtt tcccagcctt agcttggtct aacacctcat ctgcaagttt atttcccatc
     9421 acttctgttg gaacatatga cttaaacttt gtatttgtat cttttatagt accttctaca
     9481 gaagtttgat ttacaaagta taatcttgat atattctcat ctgttaattc tctatatact
     9541 tcagagaatt ttaaatcttt tattttttct gtaggcttac ctgagaattg aactatacct
     9601 actataatta taaaaacaag tagataaaaa cctgcccctt ttagcaactt attcaatata
     9661 gaagccctcc tttcatacat tgctttgccc tataatttgt taaaattaat ttttaatact
     9721 tcttttgtgt tttcatcaat tttataattt tcactgattt tataatctcc aacacatatt
     9781 attccttcac tatctgtgat tataggaatt ttacatcttt cttctcttgg gatttttaaa
     9841 tctatgaata aatctttcac ttttttactt cccatagcaa gctttatctt atcaccttgc
     9901 cttctgcttc ttattactat accccctttt accttattaa aatcaaaccc tttagatgaa
     9961 ttgtctaatt tcatactctt atacctatct atgctcatta cttgggtctc aataatttgt
    10021 tttaattctt ttattttaat aaacccatta ctaggtacat tgtaataaaa ttcaatttcc
    10081 tcattaacaa tttcctcatt cgttaatatt atactgtctt tttttctata aacaaatata
    10141 tttcttggaa gagttaacat tttatttact tttgaattat cttctaaaga cattatatct
    10201 tctatatgtc tttggtcaac aaaattagta tctcctagta tatgttttat ggaatttcta
    10261 agaactctaa ctttgatagc atcatgtaag caaacaaaat cgtctaaatt tatctctaca
    10321 aagccttttt cttttatatt tgaaacttct ctaaatttag cttctgcctc tttctcaata
    10381 taatcgttat cactttttaa actattgctc atcctcacta tagattctat tacatttgaa
    10441 ttaaaattat ccttcatata tggtaaaagg tctaacctta tcttatttct agtgtatata
    10501 ttttctaaat ttgttttatc tatcctcgga tttaaattat aagcttcaca atactcctct
    10561 atctcatttc tttccacgtc taatatgggt ctaattatgc aattatctct aatataatca
    10621 attcccttta agccttttaa acctgttcct ctcatgatac gcatcataac cgtttcggct
    10681 tggtcattga gattatgacc tattgctatt ttattggctt taatcttatc cttaatttca
    10741 taaaacattt catatcttag cttccttgct ccttcttcta atgataatcc ctcattttca
    10801 caatattttg gtacattaat agactttaca aagaatataa ttcccatatc ctcacaaagt
    10861 ttagatacat ataatgcatc tttttgagct tctatccctc ttatttgatg gtttaaatgt
    10921 gctgcatata tttctatatt aaaatctttt tttaatctat ttagtacatg caataaacaa
    10981 actgaatcag gtcctccaga aagacctaaa actattttat cgcctttttg tattaaatta
    11041 tgtttattta tagtacttag taccttatca aatatcatat ttatccctct tacacttagt
    11101 tttattcact tttaagtata ctttctataa aaaaacgcta aacccttgta tcaattttaa
    11161 gaaattaaag tttaatataa atataataat accaaataaa ttaaataaaa ggtagttttt
    11221 tcactacctt tataaaattt ctggaaaata gccatagtta ttatttagta cctatgtata
    11281 tatctatttt attcctacct aaaaataaat cttgtacctt tatattatag tctattttca
    11341 attttatgtg ttccccttct tgtatattta tatctaattc tcttgtatca atatcaatta
    11401 ataaagtacc ttgtggggtc acatactttg tagtactact ttctccacat ttaaacagca
    11461 ttgttgagtt aatagcacca aactttttga tactaacttg atttttaagt atctttatag
    11521 tattagttat ttctatatct tcttcttttt ccttgtaaat aacatatatt ccatcatttt
    11581 tataaaaaat tttaccaaag gcagtcatct ctatggtgtc catatttcct ttttcatcat
    11641 attgtctagt atttatactt atttttacac tcaacgattt ttcctccata gattcttcat
    11701 ataaactagt atttttgtat ttctactttt tgaatcttat caattttttt ctttaagaac
    11761 tctcttgcta tatctgaaaa tttttcaggt atatctgata cataatattg ataagttcca
    11821 tgaatttctg tattgtttat aatattttgc acctctaaaa tcttttttaa atcctttgca
    11881 gtctctttag ctggattaac aagttttata tgctctccaa cttcttcacc tattgttctc
    11941 tttaaaatag gataatgagt acatcctaac actaaagaat ctatattttt ttctttcaat
    12001 tcttgtaaat atatctttgc tgtcagttta gccacttctg tatttgccca tccttcttca
    12061 acaataggca caaataaagg acatgcttta ttaacaattt ctatactctc atctatttta
    12121 gatatttcca agttgtatgc ttttgaactt atagttcctt cagttcctat tattcctaca
    12181 attttgtttt ttgtagaact tacagctgtt ctagctcctg cttctataac tccaattatc
    12241 ggtatatcat atttttcttg agcttctttt aagcttcttg cagtagcagt gttacatgct
    12301 ataactatag cttttacacc ttttgttttt aaaaagttta tagcttgaaa agtatattta
    12361 attatagttt ctttggatct tgaaccatat ggtattctgg cagtatctcc aaagtatatt
    12421 atatcctcat ttggtaatat cttcattatc tcttttagaa ctgttaatcc acctaatccc
    12481 gaatcaaaaa ctcctattgg tttattgttc atctttatac aacacctact ttacattttt
    12541 gtgtttaaca acaacttatt tatcgctaaa atttatattt atattcataa ttaatatatt
    12601 attacctaaa tgattattat agtttatttt acacaaaaaa taaaggagct atcttaaatt
    12661 agaaaataat ttctacaaaa agacaactcc tttcactact taaaaattta aatttatttt
    12721 gcaaacacat gatttcctat tctcatataa ggattcaatc tatttatcca tttgcaagtg
    12781 gctatttctg gattccaaaa atatactgct ttattagttg ggtcagttcc ataaagagct
    12841 tcctgagctg ctttacgtgc tgagtctgtt ggtgccatct ttattgaacc atcaagcaca
    12901 actgagaaag catttttttg atatatgact tcttctattg tgtctggaaa tctagggtcc
    12961 aatactctat ttattactac agctgctaca gcaacctgtc cctcatagct ttctcctcta
    13021 gcttctcctg caaccaactt agataataac atcaagtcat tatcagataa atttattact
    13081 tctttctttg ctatattttt ttcttgtttg tttactttct taatattttc tgttggttca
    13141 tatgcaaata cctctttaat aggcataaat ataaaagtca aagctaatag tgtagccatc
    13201 agtttactcc acctgtccat gattaaaacc actccttaca ttcttatttt taaaattttt
    13261 tctctaaatc cttgactact tcaagtactt taaatttaat ttttactcta cttgtttttt
    13321 ttggtgtatc ttgttttatt aacttatatt ctttatcagt taaaacttcc ttcaacttat
    13381 catctgtaga tttatctatc actccattag attcatcaac aaaacatagt ggagggaaca
    13441 taacacacca ccagtttttt ccttcacctt tcccaatgat aatctttaat gctttatatt
    13501 caccagctgg aagaactata ttagaatatt gtttagtagg gaaattgcta tattgtatac
    13561 ctacctttac actgtaatta tatccatttt taagaataat atttttactt atttcttcca
    13621 aactactata ttcctttttt ataatagctt cactttcttt tatacttttt gaattttgaa
    13681 gctttggctg taaatatttt attacttcat ctctaacttt tagtttaagt tcttggtctt
    13741 catctgtatt gctgtttgct ataacatgaa atcttattaa tttatcttta taatcttttg
    13801 atatattgtc tacttttttt acctcaccat ttattactat tgtcattatt gatatgactg
    13861 atataagact taatattaat agtcccaatc taatcttaat ttttctcatt gaaaattccc
    13921 cctcaagata aatttatatc atcaattatg tccaattaaa tttaatttat tcataatatt
    13981 ttttaatact aataaaaaaa gctatcttaa aatgattaca atcattttaa aatagctttt
    14041 taaaccttat attttataag tctttactaa tcatagcctt atctatcata aactgctctg
    14101 ctttttctat atgctctgta gcatacttct tggatagctc actatcacct ttaattatag
    14161 catcaagtaa atatttatgc tcttcaacaa tattatgtga tgtatcataa gcagacatat
    14221 aggtaactct aaatctatat acttgttccc acaatgagtt tattaattgg attaattttt
    14281 tattattagt tgctttaaat atacattcat gaaattctac atcaagtttt aataacgcat
    14341 ctacatcgga ttccaaagtg ctttttttaa attcttctga tatatcttta agctttttaa
    14401 tatcttcatc actaattctt tcagcggcaa gatatgctgc taagccttct aggcttgctc
    14461 ttacttctaa tacatccata atatccttta atgacatatt tgccacatac gcaccttttc
    14521 taggcaacat aacgactaaa ccttctaatt caagctttct tattgcctct ctcactggag
    14581 tcctacttac tcctaattgt tctgctagtt gcacttccat tagcctttga ccaggcttta
    14641 attttccttc taagattgct tctcttaaat tctcaaagac tacatctctt aatggcttgt
    14701 aattatccaa gttcagttta gttaaattct ccacaaattt caaccccttt ttgactgcta
    14761 ttaacaacat acacctgttt atattttttt aataattctt tttttccaat tagagcatct
    14821 tctttatttt taaatagtcc aaaaactgta ggaccacttc cactcatcat agaacctaaa
    14881 gcattatttt tcatcattac ttgttttata tcacttattt ctttgtgttt acctatagta
    14941 acattttcaa gaatatttac catgctttct gatacagctt ttatatcttc agattttaaa
    15001 cactctatca aatatttatt atttggtctt tttttaatat tattcaaatc taatccttga
    15061 taaacttctt tagtagaaac gaataagtct ggtttgcata tcaatatatt tgtatcacat
    15121 ggtaaacctt tgatgtttgt tagcttttct ccaatacctt gagctaaggc aggtcttcct
    15181 gatatacaaa aaggaacatc tgcgcccaaa ttaagtccta tttcttttaa ttcatcttca
    15241 gataatctaa gttcccatag gtgatttaaa cctactaata ctgcggctgc attagaactt
    15301 cctccagcca tccctgctgc tacaggaata tttttttcta tgaatatttc tacacctttt
    15361 tttatataaa atttattttt aagtattttg gcagctttat aaacaatatt atcttcatct
    15421 aaaggaatat ctaaactagt gctttttacc tttatttcat cttcgtctaa ttcttttatc
    15481 tttactatat cgtataaatc tatcgtttgc attatcattt caacaaaatg ataaccgtct
    15541 tgcctttttc ccaagacatc aatggataaa tttatttttg ctctactctt tagtcttata
    15601 aaatccattc tatcctcctt gtttaaagaa taatgcatca ctaacaataa tattatacta
    15661 caaaaaataa aataataggg tattataata ccctattata cttaattact ttaaattttt
    15721 taatattaat ctactaatac gacttttttt tctaaaataa gacacttacc aggcttaatt
    15781 ggttcatcaa gttttatatc attaagttct gcaatttcat tttctgttgt attgtatttt
    15841 tttgctatat tccagaaagt atctccttct ttgcatatat atacgattat gctaggagct
    15901 ttagataaat catatacacc ttggtcttct cccttgataa taaaattttc tgctttctta
    15961 tctaatgctt cagtaaatct cttaattttg ataatcaagt ctatctggtc cctattcaaa
    16021 tcaacttcga ctttatcaat acatgctgta ttaaacacag atgctgtatc agttagatta
    16081 tccatttcta tatcatgttc aaatggaatt tcctcactaa ttttataaac caattttaaa
    16141 ccttcaactg ggacaaataa aatttcaact tttatgattc cttgtataat gcttttattt
    16201 ccttcaatat aactattttc tatagacatg gttggacaaa cgcttacaat atcttttatt
    16261 tgtatatcat cattatcatt tcttatgcct tctctaacca taaatgtttc ttcactacgt
    16321 cttaaagtct tatttaattg aataggtttg tggtcaaatt ttattatctt ttgaggcgaa
    16381 tatgcatctt gtaatacttc tcttgtaact tcatctgtaa cttttacctt acaacaagcc
    16441 atacaatcta tttctaaaag acctgtgttg ctttcactat tttgcttgaa aatatgatta
    16501 aaatctgaca tagacaacaa tacttcttca gtcataccat cactaactcc agggacttct
    16561 acaaattgag taaactcaat acctactcta tccaactcta caagttcacc ctcatatgta
    16621 caagctaacg gatttatttc taatactcca ccaataataa ctttattgtc agtcactcta
    16681 ctttctttta ctttaacaca tggatttaaa cttattatag attgaatttc ctctgtgttt
    16741 attgttatag tatctcttat agaactttct gctttttcta ttccaactat atcttgaaaa
    16801 caaatttcct ttctgtgctt ttgtatgcct tccacttgcg ccacatcttt tacaatgtct
    16861 aacctttgct tttcaaacaa acttcccctt atattcataa gagctcctac tttaatcttt
    16921 ctctcattca ttatagtaca atccatatgc tctacttctg aaaataacat gtattccata
    16981 tcttgaacaa cattgtcttt ttctattact tcgtttatat ctacttttcc gtctacatta
    17041 gaaatagtat ttttatcatc tgcaatatag attacattat aattaaaact acctctgcaa
    17101 agtatcttcc catctgccat ttcaattttt ttaagtgata tgtatccttc tgtttttaca
    17161 atttcatata catctaattt tttgtctggt acaactgcct ccgcttcaat gaatgtttga
    17221 aattttccaa agtctattct attgtcaact ttaattacat ctttaattaa ttccatagtc
    17281 tacctcctta agtattataa aaatatcaca ctatatttat atttaaggag caaaaaaaaa
    17341 attacaccta tttttaaata ggtataattt taacttattt gtaatttatc ttgatctcta
    17401 aaaacttgca actttacatt agatgttaat aaatctgagt aactataaga tactctagga
    17461 tatccattac tttcatcatc taactttata acaaacacgc ttggataaac tttttctagt
    17521 ataccctctt ttgtaataat ctgctttctt cctttattag ctttcaacaa tattttcttt
    17581 cctatatgtc tctctaagct tactcttatc ttatctagag tttgaacagt agccacaata
    17641 tcaccttctt taacgtttat atgtttacat aatatcacat ataaacattt ttgtcaaatg
    17701 tttaaactaa ttattttata tattttttgc aaaaatgtca atactatttt tgaagatata
    17761 cagtataatt atgttaattt ttgctaatgt aatattgttt ttggcattgc ccatctaaat
    17821 tttcctctgg tttcagaacc accaattccc ttaacacctg taatagtctg ctctataacc
    17881 tcatcaatag gaactactac atcaattctt gaacaagcaa ttttctccac tataaaaaca
    17941 gggtctaatg catgtatcat tatccttcca ggcgaacttg catagtttgc tcctgcactt
    18001 attatttttt cataatttga ttggcatgct cctgcgaata tgacaagatt atccaaattt
    18061 ggttgccatt tacgtgcttc ttttactgtt ttaacaaaat ttgaagagtt tctatagtta
    18121 ctcatatctt ctatatctcc tctttttatt gtcattgcat catgacctgt tattactagt
    18181 atatccggat tatatttttc tagtagtgct cttacttctt tatactgatt ttgctctgaa
    18241 acagctacac ctactgcagg tattccaagt tgagcatata catccaagca aatttttaaa
    18301 tattctttat ctccatctat ctgtagtact tttccaggca ttccatatgt gttaggattt
    18361 aattgaagtt ttggaactgc tctagtcatt cttttttgtc tttctttagc ttttcttact
    18421 gacttatata ataaattttc tacattttta tctattaata tatcttttat atcaggtgct
    18481 tttactaatt ctaggtcatc aatataagca tctgctatta ctctaaatgc aattcccttt
    18541 agtatagcta ttttctcatt attttcatct acaccaaaag agactatttt aaatactata
    18601 tctttgttat gtgactttct agctacaatg tctcctacct tcatagttaa acctccaata
    18661 aatttttatc ttagtttata ctatgttcga tataaaactt tgtttcctaa tgtcaaaaaa
    18721 acatttctta taatacttct tttatcactc ttaaagcatt tttatagtat atcttttcta
    18781 tatcatcttc actaaaccct tcttttttta gaggttcata cagtttaccc atctgagata
    18841 tatcttcaat ctcaactttt gaatctattc catcaaaatc tgaccctaga gatacaacat
    18901 ctattcctcc aacatttaca atatgtttta tgtgtctaac catatcttca agtttacttt
    18961 cacttttatc acttaaaaat aagtggaaga agtttatacc tgtaactcca cctttatttg
    19021 ctaatacttt aatcatatca tcagttaaat ttctagaatg attcatcatt gctcttgaat
    19081 tagaatgtgt agcaattatt ggtttagaag aaatctttgc aatttcataa aatccaccat
    19141 ctgaaatatg agaaacatca accaacattc ccaattcatt catcttatgt accacttctc
    19201 ttccaaaatc agtaagccct ttttctctat attctacttt attatgagga aagctcaatt
    19261 cattcacatg attccaactt attgtcatca ttctaacccc taagtcgtaa aatttcttta
    19321 aattttctaa tttaccttca agtactgcac cttcctcaat agataaaaga gctgtaagtt
    19381 taccttctga ttggtttttc ataatttctt catagttagt agctaaagct atttcatcac
    19441 tatttttttt catttcctca tgaaatttat ttgccatact catgcaataa tcaaaaggat
    19501 gttttacttc ttcagtatca acaaaaagag caaatgtttg agctaatgaa tccccctttt
    19561 tcaatctgtc tatatcaaca gaatatttat tagacttaag ttcacttgtt tctacatttt
    19621 ccattaattt tgctatagta tcacaatgta aatcaataaa tttcatattt ataccccctg
    19681 tatattttat atttatatct aaaaatagaa atagttgtcc ttatagacaa ctattgacaa
    19741 ctatttttta atattctttt taatattact taatcttatt cttcttttaa gttaggtatt
    19801 acttttttaa cttcttcaat ttgatgccat gttttatcta tattattttc actaatatat
    19861 ttttttaaat cagttaaaga tgtaaaatct ttaactgata aattgtcatc atcatctgca
    19921 aatcttaaaa taaacatgag actcccttac tttccacaac atttcttata tttttttccg
    19981 cttccacatg ggcatgaatc atttcttcct atttttgctt ctttaactat tgttttagac
    20041 ttcttataag cctttattat ttcttttctt tggtctgctg gtagtatatc ttcccaacct
    20101 tgtaaattat atagccaatg agcctcaaca gttaccatat tgttatataa tttttcccaa
    20161 tctattttta tagaaacttc tttatcagct tctacttctt ctaaaactat atcttctttt
    20221 aagctttcac ttattccatc tatgaatccc atgaaaaatt cattagtagt tccaaatttt
    20281 tcagccaatt cacttacttt accttcaaca acatccattt tattatttaa tatttcattg
    20341 tatattccag cttcaacttt caaatattct tcccagaatt ttacttctgc ttcttgactt
    20401 tcatgattat cacttaaatt tctccattca gtatataaac tcatactttt tcctcctaag
    20461 tatacctata tttttatagt ttttatagta taaaatcttt tagttagatt ggaagtttct
    20521 tctttttgat tataccatat tctatttaaa gttaactctt atattatatc ataattaaac
    20581 aattctttta atacttttat agcatactct tggtttataa aataagggct tgtcgcaatt
    20641 gttattactt tggctttttt aattaagttt tttatcttgt aaaatttgag ttcaaatggt
    20701 atatagtcca tatcacttga aaatatatcc aaatctatgt caagaacaaa ctctgattct
    20761 acttctaaat caaatccata tagactatct attattatta attctgaaaa tatgttatat
    20821 tttaaagcag gttttataaa acttcccaca tttaaaactt catttgtata tctaaataca
    20881 tcttttagat tatttacatc tacatcatag ttctcaggtt ctctagtatc cttatgttgg
    20941 tctacatgca ctaacttgca tccttttgta aactcaccct ttaacaaaga ctttgcccaa
    21001 aaataaaatg catggttatg attgtcaaac acatatatct ttttatttcc caggacatat
    21061 tcgaccatat tctccaatcc ttttgctttt atttccttat tttcatctac ttcattaaat
    21121 actacctcat tgcctaacct tacatcattt aatgtaccat ttataagttt tggaacgtat
    21181 atgctcttat tttctctttt atcatatgaa aatacattat ttcctactgg tttttctata
    21241 taaaatccac tatattcata attttccata aaactttatt tcctccattg ttatataaat
    21301 atataagtta taattttaaa aattaaaatg cacttattgt aaatcatatc atctattata
    21361 gaaaacatct tatataacta aatataatat cttctctcaa tatgtattat acaataagtg
    21421 taaaatatat ttatataaaa tatactacat tcctataaca aaaccatcag cttcaattgg
    21481 aagataacta actcttctat tcaactccac ctttccaaaa aatactaccc aatatggtct
    21541 aaaaatactt tcaattttaa ctatttcaat ctctgggatt cctcccataa acctatgagt
    21601 taatctcata gccattttat ttgcctttgc ttttactctt cgttcgtcct tatcactata
    21661 ctgcacaata ttacaatcca cattttttac aacttcatat gtaggaaaat cttgtactat
    21721 actaccagaa cctgtagaac cattcactaa aatttttaat tcatttatat cattagaata
    21781 tctcctattc ttgaaaatgg atttcgtttt gtgaatttta agtgtgataa ttttaaactc
    21841 tatataatga agtctaactt catgagcata tttgttcttt aatattagct tactaaataa
    21901 agaatttttt ccacttttag ctatctctat agcttcttct tttgtaattc ttataggtaa
    21961 cgctcttata tccataaaat cattctcttt cttatttttt tcttgtcatt tttaaaactc
    22021 tatatatata atcaaaaaat attacaatta caactgacat aactccatat ggaattattt
    22081 ttccaactat aatatcattt ctagtcaata taccataaaa tataaatcct gttattaaaa
    22141 agtacaataa tactagaaaa ccgtctattc caagccattt tatttctaaa tcttttttta
    22201 ccttagacac taatttagac atagcagttt ctccttttat agattatttt gtgtatttaa
    22261 attttcacct attctattac caatcatcca tgcaataaat gaaaaaggta tagctatcac
    22321 aagaggctct aactcaaagc tctgaactgg aaatatttta aaataaccaa aagtcactcc
    22381 accaacaatc attcctaaaa taccacccat agatgttctt cttccatttc caagaagccc
    22441 acctactata ggtacaaatg ccgaacccat ccaaatactt cctacaaata tacatgcatc
    22501 atatacattt tcaaatctaa atgctacgct aagccccata actgctgcta aacatacacc
    22561 tattctagta aactttacta attgtttctg agataactct ttttttgtaa ttcttccata
    22621 tatatcattt gctaatgtag ccccagctgc tagataatag ctatccaatg ttgatattat
    22681 agaacctaaa attcctatta taaatattac tcttattcct tgtggtaatg tatctaaaac
    22741 taaagttata tatccagcag ctggagccat ttctggataa gtagctctta ctataagtcc
    22801 tgtcatagtt aacaccatgt caaaacatat ccatagtgaa aaacaggtta ataaggctct
    22861 tcttccaacc ttaggagaat ctgctgctga aaatctttga taaaaagttg ggtctgaata
    22921 agctccaaaa gaatatacaa ttaacatcaa tgctttcata gctgacatac cctttgtagg
    22981 gtgcataagc tgtggtgcat ctttgagtgc ttctgtaaga ccttgaaacc ctcctatttg
    23041 ttcaaattga cctggcataa ccatagttaa accaaatacc atacaaaaaa acaataccat
    23101 atctgtaatg gcaactccca taagcccacc aagtactgta agtacaacga ctactcctac
    23161 cattattaat cctattaatt ctttatctat tttccatgct acgttaccta tagttcccat
    23221 agcagttatt tctccaagtt gtgcacaata tataaacatc aaaattgccc caattatagc
    23281 aacatgcttg ccataaaaac tttccagtaa atcaggaact gttatattgg ttcttatatg
    23341 aatccttgga ccaacccaca atgctaaagg cattctccca atatgtgcag ctattgacca
    23401 aactgcccat gcagatattc catatatagc cgcatactct acactaccta ctgtaccaac
    23461 tcctccatac catgatgcaa ccaaagttcc tactattaag gaccatggta aacttcgatt
    23521 tcctaggtaa taactttcca tatcttttac atttctagaa aaataataac ctattcctaa
    23581 taatataaat gcaaatataa ctataatccc attttcccaa aatgttaaca tatctaatct
    23641 ccacattctt atattttaat ttttaacttt aatatctaaa tatgaacaac tctacccatt
    23701 tccataaaaa taggtagagt tatataataa ttataagtat ttaagtaatc ttgttattaa
    23761 gcaattttat tgtttaaacc tttattttct cttttattta ttttatttaa agcataagta
    23821 gcaaatatcc ctataactgc acatactaca gataaaataa atatatatgt atatcctgtt
    23881 tgtccatatt tatctaacca attacctgca atagtgtaat aaaacgcatc tggagaaaat
    23941 cctataaatg aagcaaatcc aactactgct cctgtagttt ctaaagatat attagactct
    24001 gaaacagatg caaagtatat acctctaaat ccaaataaaa ttacacttag tattatcatg
    24061 tttattacag ctatccatat aaatcctgta ctcttaggaa taaccaagta agcagctgta
    24121 cttactgtca ttaatataaa tcctacaaac attactctta tagatgaacc aactttatct
    24181 gttataacac cagcaactgg agatgctccc atttttataa cataagttct tattattgat
    24241 aaagcagaaa ctagagtcat tggcattaca taaacttctg ataagtatgg acttaaataa
    24301 gttaaacttg agaatactaa ataagttgaa aatattataa gaccaattag ccaagccttt
    24361 ggcattgtaa ctacttttaa caatgactta atacttaatc cttcatctga tgctccacta
    24421 tcttttttct cttccactaa gaaaaataga agtataccac atattataga tgctgcagaa
    24481 tataaccata ctacatattt gaatcctact gttatttcag caaatttacc aaagaagtaa
    24541 agacctataa aagaaattaa tgtacctgat acacctgata acccttcata aaaaccaaat
    24601 attcttcctt gctctgactc acttccttgc attctaacaa ccttaacaga ggctgagaag
    24661 aaagttaata ttgttgtaaa tccccataat acaaatatta aaagtatcat actatatgat
    24721 gggaatgtag agaaataaaa tccaagtatt cctgaagcaa ttaaagaaaa agttattaat
    24781 tttctaactg agaatctatc tgcaaaccat cctcctataa aataagatac cattcctact
    24841 aatccatata aactcaataa gttccctatt tgtgtatgac ttaatgctaa agcttgttgc
    24901 attgggtcat aaaatgatga tttcatatat ggtaaactat acatagctgt tgttccaaat
    24961 gccaatatga atattatcaa aaatctttta acattatttt tgctttccat tgattctctc
    25021 tccttaaaat tttattgttt ataatctcat tcatataatt ttattttaat ttttctattg
    25081 cttgtttaaa atcatttatt atatcatttg aagattctaa tcctacagct attcttatta
    25141 gattttcccc attcatttga actaatgtat gctcttcccc taagcttgtt gctattgttg
    25201 caagctctaa agaattcatt aatcttctac tagcttggtc tcttgtcaat ccattgatac
    25261 catccttaag tttaaatgaa actacacctc cacctaaacc attcatttga gttttacaaa
    25321 gctcatattg aggatgagat tttaatgctg gatactttac caattccaca ttctcttctt
    25381 cctctaaaaa ttctgctact gctaatccat tttcacaatg ctttttcatc ctcatatcta
    25441 acgttttcat accccttaaa atcatccatg cactcattgg tggtaaagat gctcctgtaa
    25501 aacaacataa acttggccat ctaactaaat ctattaattc ttttgaacct gctactgctc
    25561 cccctaaagt atccccatgt ccatttataa acttagtaag actatgtatt actaaatctg
    25621 cacctaaatc tattggtctt tgtacaattg gtgtcccaaa agtactatca actatagcta
    25681 agcttttatt ttcatgagca atttctgcta ttgtttttat atctactaag tctaatgatg
    25741 gatttaaagg actttctata taaactattt tagtatttgg tctcattgct tcttttacat
    25801 tttgtggatt tactgcatct acaaatgtaa cttcaactcc aaatttagat aacaactcag
    25861 acatgaataa tttagtgtgt gaaaatattc catctgaact aactatatgg tcaccacttt
    25921 ttaccaatgc taatatagta gatgttattg cccccatccc tgatgtacta gatatggcac
    25981 tttctgcatt ttcaagcata gccaacttag cttctaactc tgtaagagta ggattacact
    26041 ctcttgtata cacatatccc catgtcatac acaactcttc aaaatgctct actgtctttg
    26101 cagcaaatgt tgctgtttga catattggtg tagccaatgc acctgttgtt gggtctgcac
    26161 tatgtcccca atgtattatt tttgtctcta aatcttgatt aatattgtta ctcattttga
    26221 tttcctccca ttttgactta tttatacaac gttttcccta ccaaatttca tcaatttagc
    26281 ttagtcttaa tacatttttt caagtatact tttttatttg ttataatttc taaaaatatg
    26341 acacttattt tgttttttta cagttctaat tataaactct atagtaacta tagagtcaat
    26401 atgtttttga tatttttttt acaatgttta aaatagtcag tacaaaaata ggtatatctt
    26461 agaataacta aagtcatcct aagatatacc tatttttata tcacaatata aataattaca
    26521 tataagcatt agttttttta tcataaatag atttttcaag atttatcatc ttttcataaa
    26581 tatattatag ttaaatattt taatattacc taacatctac aataaaatat actcttaaaa
    26641 taaaattata taattaaaaa tactctataa aagctaaaaa gtttttctat tcgctacatc
    26701 taaaaataat tagatagagg tataaatgta tttagtttat ttatacctct agtcttttat
    26761 aaattatatc tctactaaat tgatttttta gcacgaataa gtgtgctctt ggagatacca
    26821 gtcatcttca caacctctct atatggctta gaatttaata accccaatgc atattgtatc
    26881 tgttgattgc tgtatttctt tggcctacca tctttaaagt cctttttctt tttagcaaat
    26941 tcttttccta attgagtacg ttctattatc atatttctct caagttctgc aactgcaagt
    27001 aatgtagtca aaaagaattt acccattgaa gtattttcta aaaggcctat atttaaaata
    27061 tgaacactta cttctttagc aaataaacct tctattagtt gtattccttc tgatgtactt
    27121 ctagctagtc tatccagctt agttgcaaca agtaagtctc ccttttttag agatgatata
    27181 attttttcaa atttaggcct gtttgtagta gtgcctgtat aagtttcctt tattatttta
    27241 gcatcattat atttattcaa aatttcttgc tgttgctgat acaaactgtt gttgtctgtt
    27301 tgattttttg tacttacacg gcaatatcca tatataataa tcatcacttc ctaacataaa
    27361 gattttgtac agaagttacc cagaagcttg tttttactta tctttatcca ttttactaaa
    27421 acgatttttg ggtgtcaata ctgttaactt ttgacaccat aataattcct ttataatttg
    27481 tttgactatg tcaaaaatta ccaatataat gaaattaatg agtttataca aattggagga
    27541 aataatatga atagtctgtt aaaagaagca atagatgaat taaaaaacat ccattgcggg
    27601 gaagtttttt tattaaaaga attgttcaaa ggctatgaat ggaacaggtt ggagatgaat
    27661 atcagattga aattaggaaa actttttttg tatgaagtgg taactaatcc caatttaaat
    27721 gtagaggtca tcaataaaaa ttctgcttat cagcaaatgt ataaaaaaaa atagtgactt
    27781 aaatgtatat aatagtataa tcttcttatt gattcaaaag ttaaaacttt taatacaaaa
    27841 caatcattct attttaacat ttatcaatat gtctaaattt atataattaa cacatacgaa
    27901 tagtattgtt taaatcacat tatttaagat agataaatct taaccctact ccagcataaa
    27961 tactaaaata gggcttagaa ttatctatat ttttatccca taaaatgctt agctcttcct
    28021 cttgattgaa catatatatc tggggaaata caatagaagc gtaaatttat aaaatttcca
    28081 aagtcagaaa acttcagttc aaacttaggt ataccaaaac tttcaggtgc tatttcgtca
    28141 acgccaaaat agatgataat tccattatct gtaagataaa atgcttggtc ttcaggtata
    28201 actaactcaa cattagaata atacatttct ctattttcat ttatttgaga tttaatgtaa
    28261 tcagtaatta tattaatata atcaactcca tctctaaaaa tgtcattaag taaaagttct
    28321 tttccagttg tcaaatctat attgtaatta ttcaatgtat tgtatttagg cccatagtta
    28381 ttagcaaacc ccataaggtt taatatcata ctcagtacat aatttttatt aaaagtaact
    28441 gcgtaactgg tagataccca atagctttgt tttggaagtg aattttgaga agttgcgtta
    28501 ttatattctc gttcttcttc ctgtaagcca tttttaaaat tatttacagt cattcttaca
    28561 gcattgttta tgttatttaa aataactggg tttacatacg tggattgatt tctaatattg
    28621 tatataacag gatactttac atcatatgaa aaatacttac ttctttcaaa atcttcatta
    28681 aattgtacat ataatatatt atatgtacag gtatttgtag attgataatt ttccattaaa
    28741 atcctccccc ttttataaaa aaatcagata caatataata tgcttaaaac agtaataatg
    28801 ttaatggtaa atgtaaagaa tagaaagtat ctaaaacagc aaaaaatgac taattttgtg
    28861 gtataataca taggattgag agttatttta taggaggaaa aatatgttat tattagcaga
    28921 taaatggaaa gattatgaac ttatagatat gggaaatgga gaaaaattag aacgttgggg
    28981 aagttatgta cttagaagac cagacccaca ggttgtatgg ccaatggaat ctgaatgggc
    29041 tttatggaaa aaccctcatg gacattatca cagaagcaat aaaggtggag gtcaatggga
    29101 acacaaaaaa agatatccag aacaatggac tataaattat aaaaacttaa agtttcacat
    29161 taaaccaact ggctttaaac atactggatt attcccagag caagcagcta actgggattg
    29221 gatgatagag aaaataaaga aagctaacag acctataaaa gtgttgaatc tttttgcata
    29281 tacaggtgga gctactgtag catgtgcatc tgctggtgca gaagtatgtc atgttgatgc
    29341 tgcaaaaggt atggttaatt gggcaaaaga aaatatagaa ttatcaggtc ttaaaaatca
    29401 aacagtaaga tttatagtgg atgatgttgt aaagtttgtt gaaagagaaa taagaagagg
    29461 taaaaaatat gatgcaataa taatggaccc tccttcttat ggaagaggtc ctaaaggaga
    29521 agtatggcaa atagaagaaa agttatacag ttttgtagat ttatgtatgg gagttttatc
    29581 agataaccct ttatttttct taattaattc ttatacaaca ggattttctc caatagttct
    29641 tgaaaatgta ttgtctacaa caataggtaa aaagacaaat acaggagata tatacggtgg
    29701 ggaattagga ataccagctt ccagagatgg taagatactt ccttgtggta tatttggaag
    29761 atgggagaaa aaataatgat aaaagtcata tatgaagata accatttatt agttgtagaa
    29821 aaaccagtta acatattgtc tcaaggagat aatactaatg ataaagatat ggtaaatctt
    29881 ttaaaagact atattaaaaa aaagtataac aaacctggaa atgtatatat tggtttaata
    29941 catagattgg atagaccagt aggtggagtt atggtgtttg caaaaacatc aaaagcagca
    30001 tctagattgt ctgagcaggt aagaagtaag actttcaaaa aaacttatct agctgttgtt
    30061 catggcaaga taaaatctaa ctcagatata ctaaaagatt ttttatataa aaataaaaaa
    30121 actaatatgg taactgtagt gaaaaaaagc cataaagatg ccaaagaagc tgaacttaac
    30181 tataatgtat tagattttaa agaaaatcta agtttagttc aagttaattt aaagactggt
    30241 cgttctcatc aaataagagt tcaatttgca agcagaaaac atccattata cggagaccaa
    30301 agatatggca aagaaataaa taagattgga caacaaatat ctctttggtc caataagata
    30361 gaaatttgcc atcctactac aaaagaaaaa atggaattta catgtcatcc acctgacaaa
    30421 tatccatgga atatatttta aatctcaaat gaggtgatta tatgagtaaa aaattttcaa
    30481 taggagaaat gtctaaactt cataaaataa gcatacagac actaaggtac tatgaccaaa
    30541 tagatttatt taaacctgtt catgttgacc aagaaagcaa ttacagatat tactcaattg
    30601 accaattttc acaattagat attataaaat atttaaaata tttaggtatg cctttaaaag
    30661 aaattaagtc aaagcttgat gaaaataatg aagaaattct aaaattacta acaaataaaa
    30721 ttaatatagt ggatgaaaaa attaaagaat tagagcttat aaagaaggta ctaagcacaa
    30781 agaaagaaac tatggaaaaa ggtatgaaag tagatgaagt tggtaaaata gtgagaaaac
    30841 atattccacg aagaagtatc ttatctatag agtatgaaga aggattaagt agtgaagaaa
    30901 ctatggaact ttccagaaga caaatagcaa atatattaga agataatata tctgtgttct
    30961 atggtggagt aagtggactt gtatctatag ataaattttt aaaagaagat aaagttattt
    31021 atgacaatag ttttgttact gttgaaagag acttatttga tataaaatca caaaaacata
    31081 taacagaaat ttcatctggt gattttattt gtatgacata taaagggcct tacaaagaaa
    31141 attataccgc ttttaagaaa ctggttgatt atgttgaata taaaagaata cctattgaaa
    31201 attatatata tgaaatacct ataatagacc ctctgtctac aaacaacgaa gaggaacttc
    31261 taacagaaat tcaaatacaa gttaaaaaga gagaaattga cttaagatgt ctagtgtagt
    31321 aatctagttt acttacacat cttaatatag ttgtctatta tcaacatatg atttttctag
    31381 atagtgattc ctaacagtga gattttcaaa aaataggagg aaatatggct aatgctaatt
    31441 ccctcctatt tttaattaag ccatatcatt ttaattaagc catgtcatca cgaagtgcat
    31501 caataatatt ttcttttttt atcttattaa tagtatacaa cattgtaata aatactataa
    31561 ataaaacact aaatatacta attccaatac taaaccatgg aatcacaaaa tcaatatcat
    31621 ctgtaaccat tactttatga attagccatg aagaaattac tgctatagga agtccaaaga
    31681 acaatgctct catgccataa aaggcacact caaaattcat catcttttgg aaatcatgct
    31741 cagacattcc tacagagcga agcatggcaa gttctctacg acgtaactta atattagttg
    31801 aaattgtatt aaacacattg gcaatcgaaa tcagagaaat cataattatg aaagtataag
    31861 caaaaacatt ggcaataaaa atgtaattac ggttctcatc catcattcca tacatattgt
    31921 acagattgta ctcattcgta actccctcac tctcaataat ttgctccatt tctgcaactg
    31981 actgagtagg atttttcgat tgaaagctta aactttcaat tcctgtagaa acaccaggaa
    32041 tctcaaactt atctttggct gaataaggag ccaatactct gaagcttgct ttcttcacat
    32101 ctgaacttct gattcctgga ggagaatcag gtggcactac tttgacaaat gaaatattca
    32161 cattttgtct ctcaggtatc tccaacttgc cattagtttc aggagtgagg ctaacattca
    32221 tagaagaact gttgaaaata tcaataatat tattatcctt tgttaccata gaaacagcaa
    32281 tcagttttgc attttgtcca gtatattctt ctgctggtaa tccaagactt ttaataatat
    32341 tcagataagt tctatcatca agaaattgca tatctactgg taattcaagc atttcactca
    32401 tagaatgtga accctcatag ttcaaataat cgtctgtaag ctcacttact ttggcaacac
    32461 atgaataggt cataagtttc tgatacaaac cttcgtaaac accatttgca gtttttagct
    32521 tatcgtaaag cttcaacatt tcgttgtctt tcataccttg tgtagaaaaa ataatatcct
    32581 ggtcagtaac ctctgacctc tgatttgaca tctgttttag gtctgctact aaagcacttg
    32641 tagatataaa tagaactatg cttaaaacaa gcgacaatac aatacttcga taacgtttct
    32701 tgtttctttt aaagtttttc atagcaagaa ctccctcaag accataaact cgctgtgtta
    32761 gttttgatgt cttcacagat ttagattcaa tttttacctc atttgtctga cgaatacact
    32821 ccatcactgg tgtgttggca gcctttcttg ctggtatgta agcagaaatt aagattgtaa
    32881 ccatacttac cactgctgca acgatgattg cagggataga caatgttaat gtcaacggaa
    32941 cgtttacata gagaatattt gcaaagtttt tagctatgac agaaatcaca agtccaatac
    33001 tgactatacc gattgcaaca ccaattggta taccaatcgc accaatgcaa attccttcaa
    33061 atagcaccga atttcgtaac tgttttgctg tagctccaac agatgaaagt attccaaatt
    33121 gatgtgttcg ctcgttcaat gacatgttaa atgaattata tattagaaaa attgagccta
    33181 gcatgattat ggcaagcaca atgccaccaa ccgagtacaa aaacatattg aacaaattgt
    33241 tatcagaaac acctatgaag cgcaacacat tgtcattgaa aatggaagca tggtctttag
    33301 tgctacttat gtaagagcga atctgatgtg gatttttcaa tgtgacaaaa aggctaagac
    33361 tgtcagtctt gacttgttta tcttctttgg ttatcaaggt atatcctggt gcagaagatt
    33421 cttcaaatac gggctttcta cagataccca caactgtata agttttctta tcctgtggca
    33481 caaaaacttc actcccagca gtgtatgggt cactctgacc aagcttttca ttttcactca
    33541 ttcgtttccc tacatccaaa gaaatagtat cacctactgc aaatttgaca ccaccatctg
    33601 tcgcaacttt acttgaaaca agaatctctc tactattttc aggtaatctt ccagaaatta
    33661 aagttatagg caaagtatca aaagcttctt tgctaaatcc agcaataaaa agatatggtt
    33721 tatctggatt tctgttacct tcaagtgttg catagccaat attttcaaat gttgcagtat
    33781 ttgcaacttc atcattgact ctttgttcct gtacaaaaga agaatccaca tccaaaaact
    33841 ggacatgcca atcaccatat tttataatag ctccatttgt catatagttc atcaaagaaa
    33901 ctccaaaggt agtaactgct gtaatcatag cagctgacag aacaactcct ataattgtta
    33961 caagagttcg agtgcgattc tttttcaatc cttgcagagc aactttgtta aaaatgttca
    34021 ttaacgattc accttcctct catcacgcac tacttttcca tctgaaatac agataattct
    34081 atctgcctgt aaagcaatgt tttcatcatg tgtgacaata atgagagttt ggtgatattt
    34141 actatggctc tctttcagta actggataat ctcttgtcca tttttactgt ctaagctacc
    34201 tgtaggctca tcagcaagca taactgctgg tgcattcatc aatgcacgac caatggcaac
    34261 acgttgctgt tggccaccag aaagttgatt tggtaaatgt gtttttcgtt cttttaaacc
    34321 aagcaattct aacaagtcat ttaaccgttc ttgattgacc ttacgcttat ccataagtat
    34381 aggcaatgtg atattttcta ctacatttaa tgtgggtatc agattgtgaa actgataaat
    34441 caatccaact tgtcgcctac gaaaaatagc aagtttttca ttgctttggc catatacatc
    34501 ttgcccctcc agatatatct ttccacttgt tggtacgtct actcctgcaa tggaatgtag
    34561 tagtgtagat ttaccagaac cagaagaacc aatgattgca gtaaactctc ctttttcaat
    34621 agtaagtgag acatggtcaa gtgcagtaac cttattttca ttcttaccat aaaccttaca
    34681 taaatcttca atctttaaaa acgccattat ataagtctcc tttcatattt tataaatata
    34741 tcataggact ttcaacttac atttaagtga catttaaatg agagattcgt cactttggaa
    34801 aacgaataac aaatattgca ccaccttgtg ggtgattttg tgcagtaatt gttcctcctt
    34861 gtctcataat aatcgtctta caaagtgcca atcctattcc ataaccggct gtgcttgaat
    34921 ttttcccacg ataaaatctg ttaaatagac atggtaaatc ttctttttta aagcctgctc
    34981 cgttgtcatg aatagtaagt tgagtaaaca aaaagttgtc ctcacaaatg atatcaattt
    35041 ttccattatc acccacactc tccatgcagt ttttaaatat attttgaatt gcttctgaaa
    35101 gccaatttaa atcacccaaa atccttactc cttttggtat atcaatatgt aaagtgatat
    35161 tgtgcagttc catgggaatc aaaagttgat gaagtgcaga actaatcaaa ttattcacat
    35221 caatttgttc tttttgaaag actacaatac ctgcatctaa acgtgataat tttaaaaggg
    35281 aagtaatcag ccagtccatt cgtataagta attcctctgt ttctcgtatc aactcttttc
    35341 tctcatcttc atcagaagta ttctctaaca gtgacaaaat aagagttact gatgtaagag
    35401 gagtgcgaag ctggtgggct atgtcagcta gtgagtcagc aaggtgttct ttttcttttt
    35461 tcaatgcgta attttgctct ctaatacgta acgtcatttt agttatttca ctttgcagaa
    35521 tagaaagttc accctcatct gattcagcaa tatacagatg gttagcatta tgaagcacaa
    35581 gattaatttg ttctgaaatc tgtgcaatac ttttgtatcg atttttagta aacacaaaaa
    35641 atgctattcc aaaggtagtg gcagaaacaa tagaaagtat tccagtcata atactgattg
    35701 caaatcccag ggctacagtg agaatagtaa ttaataagaa taaaatagca aattttcgaa
    35761 actctctatt tcgaaacata acttcccccc aatctatacc ctgtcccacg aacagtcaaa
    35821 attatttgtg gacttgaagg gtcatcttct atcttctctc gcaagcgttt gatgtacaca
    35881 gtcaatgtgt tgtcattaac aaactcacct gccgcatccc acaattcatc aagtaatctt
    35941 accctcgtaa taatactttt aggattgcta ataaacacca ataacaaacg gtattctaaa
    36001 gctgaaagaa aaacctcatt gccattcttt ttcacaacac cggttgccgt atctacataa
    36061 agcccacaaa tttcaaaagt tgacccaaaa cgcccacttt ttcgtagtgc tgttctaatt
    36121 cgcgcaatca gttcacgtgg acgaaaaggt ttagtaatat aatcatctgc acccatattc
    36181 agtccagtaa caacacttga ttcatcaccg gaagctgtca aaaagataac aggaatgtct
    36241 tgcttttctt tgatttctgt gcaaatcgta aacccatttc catcaggtaa agaaatatca
    36301 ataagtgcca aatcaaattt attcttagca atctctacaa gtgcttcact tcttgtggat
    36361 acatgggtta ctataaatcc ttctgaatta agcaaaagaa taagattttt ggcaattgct
    36421 ttatcatcct caactaaaaa tatccgtttc atttactttc atcctccttt attttattag
    36481 ttttatatat tccagcagag caatagtaca ctactatttt acttatcatt acacaatttt
    36541 cagtagtttc ttttgttctt atataatcca tgcataatac ctccattgat ttattatatt
    36601 tcttataaca taaatacaca agataagaca aaaaacataa tgtaagtgca agttttttaa
    36661 ctcactaact tataaacata cactcctact aacactactt tcttgatgac acatcttaca
    36721 agcttatatt catacatcaa tgaaaaatta aatttatcca tttattaaaa taaaaggcaa
    36781 tagcttctat agctaatgcc ctttatctta aaatgattta aatactatac aatttttata
    36841 aatggctata aataaactcg tatagaatat aaaatttatc tacagtcttt tgttatacaa
    36901 aatttataac ctcttataga acaaatttac cactttgcaa acttatcact tttactcagc
    36961 tatattataa acttttaatt tatctttgtt taaatgtttc ttcttaactt ctactaaagc
    37021 ttttagcgta tccaaagatg tcattatttc agtagaaaat tcaatggctg ttcttctcat
    37081 cttaaatcca tctcttgtag agtcatttcc tttagttggt gtatttatta ctatatcaac
    37141 ttgtttattt cttatagcat ctaatatgtt tggtctaggc tcttcaattc tatttactat
    37201 atcagcctct attccatttt ctcttaaact cttcgctgtt ccttctgtag caacaaaagt
    37261 atatcctaat tctttcatat cttttgctat ctctataaac tcatctttat catgattatt
    37321 tacagtagca agtactactc ctctttcatc agacatatgt ctacctgctg ccaagaaccc
    37381 tttatataag gcttcttcta aattttctcc tacacctaga acttctcctg tagacttcat
    37441 ttcaggtcct agacttactt caactttaga taatttagac attgagaata ctggtacttt
    37501 tactgatact aattttggct ctttgtaaac tcctgtacta tatcctaaat cctttaattt
    37561 agctcctaac atacacttag tagccaagtc aactattggt actccactta ctttacttat
    37621 atatggaact gttctactag ctctagggtt aacctcaatt atatataatt cattttgaaa
    37681 ttctataaat tgtatattaa ccataccaag cacattaagg tctaaagcta tttttttagt
    37741 gtattctact attttttctt ttatttcatc agatatattt tgacttggat acattgttgt
    37801 actatctcca gagtgaactc cagctctttc taaatgctcc attataccag gtatcaatat
    37861 atcttcttta tcacatatag catctacttc tatttctcta ccagttagat atttatctat
    37921 aagtactgga tttttatggt ctctatcaaa tgcatcatcc aaatactgaa ttagtttttc
    37981 ttcgttataa gttatttcca taccttgacc accaagtaca taagatggtc taactaatac
    38041 tggataacct aactccttag caatttcaac accttcatta gttgtccata caccttttcc
    38101 ttttggtcta tttatatcta gtctctctag taaatcatca aatttttctc tatcttctgc
    38161 tgcatctata tctctaaagt ctgttcccag tataggtata tttttttcat gtaaaaactt
    38221 agccaatttt atagctgttt gtccaccaaa ctgtagtatt acaccttctg gtttttcttt
    38281 ttctattata tttaaaactt cttcttctgt taatggttca aaatacaact tatcagatgt
    38341 atcaaaatcc gtacttacag tttcagggtt attgtttaca attatagttt ctattcccat
    38401 ttttcttaaa gattttacac agtgaactga acaatagtca aattctattc cttgacctat
    38461 tcttattgga ccagaaccca atactacaac ttttctctta tcactaacta ctacctcatc
    38521 atattgttca taagttgaat agtaataagg tgatagagct tcaaattctc ctccacatgt
    38581 atcaaccatt ttataaactg gttgtatatt atataaactt ctcaattcat ataatttttc
    38641 tgggcttatc ttcattaagt cagatatacc tttatcagaa aatccctttt tctttaattc
    38701 atgtaaatat tctttatcta agtcttctat ttttagaact tttaactttt cttcttgttc
    38761 tactatccat ttaaatttat ttataaacca cttatcaaca ccagttattt ctgatatcat
    38821 ttctacttta tagcctcttc ttatcatttc agctaagtca aatagtctct catcatcagg
    38881 tactactact ctagccttta attcttctaa tgttctacct tctgatggag catgaaccaa
    38941 tgaatatttt cctgtttcaa gtgatcttat acctttaaga atagcagcct caaagttact
    39001 tcctatactc atgatttcac cagttgccat catcttagtt cctaattttc tattggcatg
    39061 tctaaattta tcaaatggcc actttggtat ttttactacc acataatcta atgttggctc
    39121 aaaacaagca taagtttttt tagttactgc attttctatc tcatccaaag tataacctaa
    39181 agctatctta gctgctactt ttgctattgg gtatcctgta gcttttgatg ctagggctga
    39241 tgacctacta actcttggat ttatttctat tatcgcatat tctaaactat gtgggtttaa
    39301 agctatttga acgttacatc caccttgaac ctctattgca tttattatgt ctattgatgc
    39361 ctttctaagt agttgatact cttcatcact tagagtttga cttggagcaa caactatact
    39421 gtctcccgta tgaactccaa ctgggtctac attttccata ttacatacag ttatacagtt
    39481 tccatttcca tccctcatta cttcgtattc tatttctttc caacctttta tactcttttc
    39541 aagaagaact tgtccaacag gacttagctg tagtccatgt gaaagtattt ctcttaattc
    39601 ttcctcagta tcagctatac ctccaccagt tccacctagc gtatatgctg gtcttacaac
    39661 tactggatat cctatcttat tggcaaactc aagacctgct tctaaatttg taactatatc
    39721 actaactatt actggttgat ttatttcttt cattacttct ctaaataaat ctctatcttc
    39781 gccctttttt atagattcta tagatgttcc tataactttt acattatatt tatctaatat
    39841 accagcatca tgtaattcta cagctaagtt taatcctgtc tgaccaccca tacctgcaag
    39901 taaactatct ggtttttctt tttctattat tttttctata aattctattg ttaatggttc
    39961 tatatatatt ttatctgcaa tttctttatc agtcattata gtagctgggt tactatttac
    40021 taatacaact tcaattccct cttcttttaa tgcttggcag gcctgtgttc ctgaatagtc
    40081 aaactctgca gcttgaccta ttattattgg ccctgaccct aatactaaag ttttctttat
    40141 actatctaat ttaggcataa ctctttctcc ttatctaaac aattttcaca gttcttatct
    40201 tcatcatcta tacaatcaac tttaattact ttattttatc ttaaattcaa atttactcat
    40261 caatacatct atttaataca tctatgttaa ttaaaccaaa ctttttgatt taagttattc
    40321 ttgtttttta gttagctatt ctaatgttat ttattttact aattctaaaa atttatcaaa
    40381 aatatagtca ttatcttttg gtcctgggca agcttcagga tggtattgaa cactgtatac
    40441 atctagtttc tcatgtctca ttccttcaac agtattatca tttaaattta tatgtgtcac
    40501 tttcatttgt tcaggaactt ctgaaacata ataaccatga ttttgagaag ttataaatac
    40561 ttttccttct tctaaatctt taactggatg atttccacct ctatgcccaa atttaagttt
    40621 agcagttttt cctccaagag ctaaagctaa aagttgatgt cctaagcata ttccaactat
    40681 aggtttttta ccaataagag cttttatatt ttctataaca tcttctaggt cttctgggtc
    40741 tccaggtcca tttgacaaga atattaagtc agggtttata ctcaatacat cttctggaga
    40801 tgttgtagct ggaaatattg ttatatcaca tccacgagct ataaatgatc ttaatatatt
    40861 tctttttact ccaaaatcca taacagccac ttttggacca tttcccttta tatgctctac
    40921 ttcttttctt gtaacagttc taactgcttc tgtatttgaa aacttatcca atttatgttt
    40981 aacatcttct aatttactgt cttctaatgt aattatacct ttcatggttc cattatttct
    41041 aagtatctta gtcaaagctc ttgtatctat tccttcaagt ccgataactt tattttgctt
    41101 taaatattgg tctatatcaa tttcacatct aaaattactt ggagaatcac ttttctccct
    41161 tactatgaat ccctttactt gaactttttc agactctgct gatgataaat ttataccata
    41221 atttcctaca agaggataag tcatagtaac tatttgacca tagtaagaag ggtctgttaa
    41281 aacttcacca tatcctatca ttgaagtatt aaatactact tctcctacac tttcttctaa
    41341 atatccaaat gcctttccta taaaaactgt tccatcttct aatattaacc ttgctttcat
    41401 actacagtac ctcctataat tctctttaga caaactaaag aacattaact aaatataagc
    41461 ttttaaatat ctatatctat ttttcacttt tacattctag ttttatactt atttacattt
    41521 attttttatc tttttctatt atactacaaa tttcttaaaa aaaagaagtt atctcaaaag
    41581 taaaaactcc tagaaaaaat aacctctttt ttttatttaa taattaaatt cttaaactat
    41641 acaatcaact taatttctat tcagctatat tgtaaacttt taactcatct ttatttaaat
    41701 gtttcttctt aacttctact aaagctttta gtgtatccaa agatgtcatt atttcagtag
    41761 aaaattcaat agctgttctt cttatcttaa atccatctct tgtagagtca tttcctttag
    41821 ttggtgtatt tattactata tcaacttgtt tatttcttat agcatctaat atgtttggtc
    41881 tagattcttc tactctattt actatatcag cctctattcc attttctctt aagctattag
    41941 ctgttccttc tgtagcaaca aaagtatatc ctaattcttt catatctttt gctatctcta
    42001 taaactcatc tttatcatga ttatttacag tagcaagtac tactcctctt tcatcagaca
    42061 tatgtctacc tgctgccaag aaccctttat ataaggcttc ttctaaattt tctcctacac
    42121 ctaggacttc tcctgtagac ttcatttcag gtcctagact tacttcaact ttagataatt
    42181 tagacattga gaatactggt acttttactg atactaattt tggctctttg taaactcctg
    42241 taccatatcc taaatccttt aatttagctc ctaacataca cttagtagcc aagtcaacta
    42301 ttggtactcc acttacttta cttatatacg gaactgttct actagctcta gggttaacct
    42361 caattatata taattcattt tgaaattcta taaactgtat attaaccata ccaagcacat
    42421 taaggtctaa agctattttt ttagtgtatt ctactatctt ttcttttatt tcatcagata
    42481 tattttgact tggatacatt gttgtactat ctccagagtg aactccagct ctttctaaat
    42541 gttccattat accaggtatc aatatatctt ccttatcaca tatagcatct acttctattt
    42601 ctctaccagt tagatattta tctataagta ctggattttt atggtctcta tcaaatgcat
    42661 cttgtaggta ttgagataat ttttcttcgt tataagttat ttccatacct tgaccaccaa
    42721 gtacataaga tggtctaact aatactggat aacctaactc attagcaact tcaatacctt
    42781 cgttaagtga ccatacaccc tttccttttg gtctatttat atctagtctc tctagtaaat
    42841 catcaaattt ttctctatct tctgctgcat ctatatcatc aaaatcagtt cccagtatag
    42901 gtatattttt ttcatgtaaa aatttagcca attttatagc tgtttgtcca ccaaactgta
    42961 gtattacacc ttctggtttt tctttttcta ttatacttaa aacttcttct tctgttaatg
    43021 gttcaaaata cagcttatct gatgtatcaa agtctgtact tacagtttca gggttattgt
    43081 ttatgattat agtttctatg tccatttttc ttaaagattt tacacagtga actgaacaat
    43141 agtcaaattc tataccttga cctattctta ttggaccaga acctaatact atcacctttt
    43201 tcttatcact aacaactacc tcatcatatt gctcataagt tgaataatag taaggagata
    43261 tagcatctat ctcacctgca caagtatcaa ccattttata tgctggtttg atattgtata
    43321 gacttctcaa ttcatataat ttttctggac ttatcttcat taggtcagat atacctttat
    43381 cagagaatcc ctttttcttt aattcaagaa gatagtcttt agttaaatct tcaattttca
    43441 taacttttaa tttttcttct tgctctacta tccatttaaa tttatttata aaccatttat
    43501 ctatacctgt aatttgttct atcatttcta ctttatagcc tcttcttatc atttcagcta
    43561 aatcaaatag tctctcatca tcaggtacta caactctttt ctttaattcc tcaatgcttc
    43621 tctcctcaga tggtgtgtga actaatgaat attttcctgt ttcaagtgat cttatccctt
    43681 taagaatagc agcctcaaaa ttacttccta tactcataat ttcaccagtt gccatcatct
    43741 tagttcctaa ttttctattt gcttttttaa atttatcaaa aggccatttt ggtatttttg
    43801 ccaccacata atctatagtt ggttcaaaac aagcataagt ttttttagtt actgcatttt
    43861 ctatctcatc taaagtataa cctaaagcta tttttgatga aactttagct attggatatc
    43921 ctgtagcttt tgatgctaaa gctgatgacc tactaactct tggatttatc tctataactg
    43981 catattcaaa actatgtgga ttaagtgcaa attgaacgtt acaaccacct tgaacttcta
    44041 ctgcatttaa tatatctaaa gatgcttttt taagcattgc acattctttg ttacttaaag
    44101 tttgagttgg agcaacaact atactgtctc ctgtatgaac tccgactggg tctatatttt
    44161 ccatgttaca tacaactata caatttccct ttgaatctct tattacctca tattctattt
    44221 ctttccaacc ttttatactc ttttcaatta atacttgtcc aacaggactt aattgtagac
    44281 catgtgaaag tatttctctt aattcttcct cattatcagc tataccccca ccagttccac
    44341 ctagtgtgta tgctggtctt acaactactg gataaccaat tgtaagtgca taatcaagac
    44401 ctgcttgtaa atctgtaact atatcactaa ctattacagg ctgatttatt tctttcatta
    44461 cttctctaaa tatatctcta tcttcacctt ttttgataga ttctactgaa gtacctatta
    44521 tttttactcc atatttatct agtatgcctt tttcataaag ttcaactgct aggtttagcc
    44581 ctgtttgtcc acccatacct gcaagtaaac tgtctggtct ttctttttct attatttttt
    44641 ctataaattc tattgttaat ggttctatat atattttatc tgccacttct ttatcagtca
    44701 ttatagtggc tggattacta tttattaata caacttcaat cccttcctct ttcaaagact
    44761 ggcaagcttg tgttcctgaa tagtcaaact ctgcagcttg acctattatt attggtcctg
    44821 accctaatac taaagttttc tttatactat ctaatttagg cataaatttt tctccttatc
    44881 taaatggttt ttactatctg taaataatac taaatctata ttaatgctaa gaatttatta
    44941 aatatacaat ctaaatcttc ttttgttgtg tattctggaa tgtactgaac actatatatt
    45001 ggtaattcct tatgtctcat tccttctata gtattgtcat ttaaatttat gtgagttact
    45061 tctgtatttt ctggcatttc tgaaacatta tatccatgat tttgagaagt tataaatacc
    45121 tttccagttt ctaaacattt aactgggtga ttacctcctc tatgtccaaa tacaagcttt
    45181 gaagtctttc ctcctaatgc caatgctaaa atttgatgtc ctaaacctat tcctgtcaat
    45241 ggctttttgc ctattaattt ttttatattt tcaactatat catttatatc ctctggattt
    45301 cctgggccat tagataataa gattaagtca ggatttatat ttaaaatttc ttctactgta
    45361 gtcattgctg gtactatagt tatatcacag ttacaagcct taagagactc tagtacacta
    45421 tttttaacac caaagtctat aactacaact ttagctccag taccttttat attttcaatt
    45481 tcttttcttg taacattttt tactgaatct ttgttacaat gctcttctaa tttagactga
    45541 acatcttgta atgatacatt ttctaaagtt ataattcctc tcttagttcc attgtttcta
    45601 ataattttag ttaatgctct tgtatctatt ccttcaagtc ctattacctt attttgcttt
    45661 agatatgtgt ctatatccat ttcacatcta aaattatttg ggttatcact tttttctctt
    45721 acaataagtc cttttacttg caccttattt gattcaacat cttctaaatt tattccatag
    45781 tttcctataa gtggataagt catagtaact atttgtccat aataagttgc atctgtcaat
    45841 agttctccat acccagccat tgaagtatta aatacaactt ctccaatagc ttcctttaga
    45901 tatccaaatg cttttccttc aaatactgtt ccatcttcta aaattaattt ccccttcatg
    45961 taagctacct cccaaatatt ttatctaagc attttctatt tctcttacaa tattaatagc
    46021 tgattctctt ggattttctg cttttgttat aggtcttcca acaactaaat aatgagcacc
    46081 tttttttatt gcatctgatg gagttacaac tcttttttgg tctccaacct ctgctgattt
    46141 aggtcttatt cctgggcaaa ctgttataaa atcagttcca catgcttcta ctattttatc
    46201 tacttcttgc gctgaacaaa caaccccatc tattcctgat tcttttgcca gtttagctct
    46261 ctttatagct aactcttctg ttgtcatatt acatcctatg tcctgtaaat cttggttgct
    46321 taatgaagtt aaaactgtta ctccaactac taatggcttt tctatattta atctttctgc
    46381 ttcttcccta gcaattagtg cacattgtct cattccttcc atatctgata catgtattgt
    46441 cattaaccaa acattatctc tcactgcagc tttcactgca cttttcatag tatttggtat
    46501 atcatggaat ttaaggtcta aaaatatttt tttacctttt tctttaagat aatctattgt
    46561 tttacctttt gtggcaacgt attgctctag ccctacctta aatatgtcta cactatcttc
    46621 taatctgtct attagttctt tagctttatc aaattcgtca gtatcaattg caactatcaa
    46681 tttttcttta ccatttatca tttttacatc tcctttttaa taaagcctaa ataatcataa
    46741 aaaaatcctc acaccaaaag aggcataagg attttatcta tacataactc tattcattag
    46801 ctatgagata tctttcccag tctctctgga ctagtttaaa agactttatt atatttaaat
    46861 ttttatttta tactcatcaa aaacctctag aagatttact agaggttata tactaacatt
    46921 atctataacc ctttagtctc tctggactac tttaaggaat ttagctgtaa tatttttctt
    46981 tatttatata actttatgta tctataggat aatttaaagt tttatctttt ttataattaa
    47041 accactaatt gctttttatg tcaataagtc tttgaattat tcttcatctt tatcaaacaa
    47101 ttttttctca aaatatgatt ctgcattata tattgcagca actggattat gcccagttac
    47161 tctatctttg acaactaaag ttgttatagg agcttccata tatttcatgg ctaaagtatc
    47221 gtgaccaaca cataatccaa gaattacatt aaggtcaacc ttagcttcat ttaaaaataa
    47281 agcttgtcct attggattgc acattacctc atctgaacac tttgatattg tttgagatgc
    47341 ttctagtcca attgtactct taggcattgc cccattttta catataacag aaaatacttc
    47401 aaacccatga tgttcaaata ttttttgcac tgtttgcatt tctcttttta gtccaataca
    47461 aaatgctatg ccaatctttt tataaccaca ctttttagca aactctataa tctcttttag
    47521 tctagtatat tgacaatacc cctctgcttc aactaatcca gcattataag ctatttttct
    47581 attctcttct tcttcataaa gttgctttgc tttttgttgt agttcaattt ctctagttgg
    47641 acatatcttc attaatttat ccatatttcc attagaacag cctctaagat tacattttcc
    47701 acacttatac atatccaata tccccttcca aaattttatt catcttgcga ttcttctttt
    47761 tctagagtta cattttcttc ttgggtttct tcttctggtt tcacatgctc gactacagtt
    47821 ataaaatatg attttcctat tttattcctt ataggaagtt tttcatatga aacatctatt
    47881 ttatttttta tacaagctat atcaaaatgt cttaaggcta cacctaagct aaccttattc
    47941 atatcttcac agtgtttctt aggtctcttt tcaaataaat gaagacctcg ttcatcctta
    48001 tggaaatacc acggttgaga attttttaca gatggagctc ttcttgtcaa ttctaagata
    48061 tctttccact ttctattcct atttatctta tttatcatat cttttactgg ctttctatca
    48121 ggtctagcat atctcgtcct aaacaactct tcattttttg ctggatatcc aaatgctatt
    48181 attatataag gattttctat tttgttttca tcatcttctt ctgtttttat tccagctaga
    48241 taatctaaat catcttcctc atcttcttca aaattcttat tcccaatatc tacaaattcc
    48301 aagatatctt ctctctttaa gtttccttcc aaccagcaag tagctattcc caatgttgta
    48361 aggcgcaaaa ctacaccttc tgtagcaaat cctatattct gtaaatagtc ctcacctttg
    48421 tctgatgtaa ctactatata atgaggtgcc tttactttac attccttacc catcaaaaaa
    48481 tgtattatat gacctctatc aacaacatgt gctttaatat ttaaatcttc atttaagtat
    48541 tctaaatttt tacaacttct ttttatttct tccatcaatg gcttttttat cttcttactg
    48601 gaaaaatttc ttacagattt tctataaaaa atggcttcat aaagctccat ttatgccctc
    48661 ctaactgaaa tcttctgacg tataaactct ataaatttat ataaatactt tatatttttt
    48721 atagttttat ttcctttttc ctcctgccct attttgaaat tcataagaat atctactcta
    48781 gtttaatata gcattcaaaa ggcttaaatt ctaccttatc aatgtctata cattagcata
    48841 atttttttat ttgattttct atgctaattt aaataacaac actagctatt acctttttaa
    48901 ttaagctttg ccagaaaaat tttttttcat ttataaatat ctatctcatt attatattat
    48961 aagttttttt cggtattctt gtatagcttt tcactaaaaa agtattttta tttctacttt
    49021 aatattatta tcaacaaaaa acatactgct taaataagtt tgttatcctc ataatttgtt
    49081 ttaattaaaa tatttttttt atttctcaat ctataaagta taaatatttt gaatatgacc
    49141 caaaatctaa gtaaagttat aatattttat aagttgttca atattaaaaa cataagtaat
    49201 gttataatac tttataagtt attcaatatt aaaaatatag gaggataaat atgaatttaa
    49261 atagaaattt agaaaaatac gctgaattag caataaaagt tggagttaac atacagccag
    49321 gtcaaattct acttataaag tcaccaatag aatgtgctga ttttgcaaga aatgcactta
    49381 aagaagcata taaatgtggt gctaaaaatg tttatataga gtggtctgat gaagaaagta
    49441 ctcttattaa atacttatat gctccagatg aagcatttca tgagttcccc aaatggacag
    49501 cagaacaata tgtagatata gcaaaagaag gtggggcatt tttatcagtc tatgcccaaa
    49561 atccagattt attaaaagat gttgaccctg aaagagttgc aaattttcag aaggcatctg
    49621 gaaaagcttt aaaagaatgg cgttcttaca ctctaactga taaatgtaaa tggaatatag
    49681 tctctgtgcc aacaaaagat tgggcaaaaa aagtgtttcc aaatttatca gaagataaag
    49741 caatagaaaa actgtgggat gctatattta aatgttcaag agtagatggt caggacccta
    49801 taaaagcatg ggaagaacat aatgaaaatc ttaaatctaa aatggacttt ctaaataaaa
    49861 ataactttaa aactttaaaa tataaatcct caaaaactga tttgactcta gacttgccaa
    49921 agggtcatgt ttggctaagt ggagcatcca aagaccctaa tggaataagt tttaatccga
    49981 atattccaac tgaagagatt tttggaatgc cacataagtt taaagtaaat ggaactgttt
    50041 atagtacaaa acctcttgtt tatggtggaa acataattga caatttcttc ttaacattta
    50101 aagatggtaa aataatagat ttctctgctg aaaagggact agatacacta gaaaaactta
    50161 ttgaaacgga tgaaggctct cattatttag gagaagtcgc tcttgttcca tacaactcac
    50221 caatatccaa tacggatata attttttata atactctata tgatgaaaat gcttcttgcc
    50281 actttgcaat tggttctgct tataagactt gtctggaagg tggaaataat ttaaaagatg
    50341 aagaattgga tgaacatggt gtaaatgaca gtttaacaca tgtagatttt atgattggtt
    50401 ctgctgatat ggatattatt ggtgagactt atgatggaaa gcaaatacag atttttaaaa
    50461 atggtaattg ggctttttaa catatgattt taactaaaaa gggctgatgg aagttatacc
    50521 agacttccca gcccttttta atgttgatga taaatatttt ttatattaat taatctcatt
    50581 attatagatt aattcctatt gttttaaaca taagtatcta aaacttatat ttatattata
    50641 tataaaatat cctatttagt aaaaccttta ttttaattta tatgctaaaa atttaacttt
    50701 gctatttcaa cagcagactt tgcatccttt gaataataat cagcacccat ttcttcagcg
    50761 tattcttctg tcaaaactgc acctcctaca aatacctttg catttatctc attatctctc
    50821 agtgcctgaa ttgtatcttt catactttga acagtcgtag tcataagtgc acttaatcct
    50881 actaatttta tatttctctt tttagcaact tccactactt cttcaatagg gacatcttta
    50941 cctaaatcta taacttcata tccataattt tctagcatta tttttactat atttttccca
    51001 atatcatgga tatcaccttt tactgtagca actattattt ttcctttgga tacattattg
    51061 ctacttttac ttaataaagt ttcctttatt gtatttaatg aaacttttac cgtttctgct
    51121 gattgaatca attgtggtaa aaatatatct ccactatcat atctttttcc tactttatca
    51181 agagcaggaa ttaaaatctc atctaatata taattttcat ccttctcttt taaaagattc
    51241 agtgttacat tttttgcttc atcttttaat cctctttcaa ctaaaatatc caagggcaaa
    51301 tctttatcaa tctttgtaga tgaatccgat ttttttgaat tatttatatt gctatattga
    51361 tttatatagt ttatacatcc tttatctgtg ttatttaata ttttaaaaga attgatagct
    51421 tccatcatac tatattcatt tggatttata attgctaaat caagccctgc ccctaaagct
    51481 aatgttagaa aagaagcatt aagtgctttc ctatttggaa gaccaaatga aatatttgaa
    51541 acacctaata tagtttttac tcctagtgtc tttaccattg ttatagcttt tatagtttct
    51601 attgcttctt cttgttgtgc tgaaacagtt aatgataaac agtctataaa tatatctttt
    51661 ggttttatcc cataagaaac tgctctatta actatccttt ttgctatttc aaatctttct
    51721 tcagcctttt taggtatccc cttttcatca agtgtaagtc caaccacaca tgaaccatac
    51781 tttttaacta ttggtaatat actttctaaa gactcctctt tgccatttac agagtttact
    51841 attgttctac cattataata tctaagtcct tgctctaagg cctctacatt ggaagaatca
    51901 acttgtaaag gtgtatctac tactgcttga atctctctta ttaattttgg cattagtttt
    51961 ttttcatcaa tctctggaag accaacattt actccaagta tttgtgctcc agcatttact
    52021 tgctctaaac ctaaatttat agcataatca acattttcat tttttaatgc ttcttgtaga
    52081 gattttctac ctgtgggatt caatctttct ccaacaactg taggcgattg tacttccaca
    52141 aattttgatg gtgaacagac tacacattta tcaattttct cgatacatcc ctttgtaaca
    52201 gaatttatat tctcagatat ttcttttata aaacttggat tcgtaccaca acatccacct
    52261 attatagtag caccaacttc aacgaacttt ttaacccctt caaaaaattc ttttgcatcg
    52321 acatcatata tagcctctcc atcaactata tttggaagac ctgcatttgc ttgaaccata
    52381 acagggactg tagctcttga tgctattttt tcaactattg gtaaaagttg tttaggtcct
    52441 aatgaacaat taactcctat tgcatctaca cctagacctt ctatagtagc caccatacat
    52501 tctggcatac atccagtaaa acttcttcca ccttcatcaa atgtcatagt acagaaaata
    52561 ggtaaatcag agttttcttt tgctgctaat acagctactt tagcttcata taaatccatc
    52621 atagtctcta ttactattac atcaactcca gatttaacgc cttgtagtac ttgtctttta
    52681 aatatttcat atgctttatc aaaacttaaa gtacccatag gctctagcat ttctcctata
    52741 ggaccaatat ctaaagctac atatcttggt ttagtattat ctacattttc tatagctttt
    52801 ctagccacca aaacagcatt gtcaatcact tcttctacag tatacttact atctaatttt
    52861 agttcattac atccaaaagt atttgtaaga attacattcg aacctgcctc taagtatgct
    52921 gtatgtattt ctataagttt atctggattt tgaagaccaa atacttctgg attttcacct
    52981 aactttaacc ctttttgttg aagcattgtt cccattgcac catcaaatat taatatatta
    53041 tttttcagat attgtcttat ttccacaaga gttcgctccc tttctatatg tacagtttct
    53101 atagttttta caattttcac acgacttttc tttcttagat ttatttattc ttgtattaga
    53161 aatacctata atagccacta ctgactttct cggtatcata attccattag aagtaattgt
    53221 tagacctatt tgtttttgag cattcaaaac gtttaatata tctatatttt tttctattgg
    53281 taaatctcca tatcctgggc tatatcgcat agttataaat ttatcttgct ttaaaaaaac
    53341 cttttctaaa ttattttgaa caatgtcaca cacttcttct attgctgttg ttccacatga
    53401 atcaattatt agtccttttg ttaaatttga ataagagtgt cgtcttattt ctttttctat
    53461 atctatccct atagtagctg ccataattac acactcatta cattctttta aaagttcata
    53521 tacatattta ctctctaatg ttaaatttgt tccctctaat tctacaacat tatctttatt
    53581 tattctaata ggataaatcc tagataaata tctaggattt attttatttt tagttatagc
    53641 tacacattca tcaatagtat atttaaggtc tttatctatc tcttgacctc tgtattgtaa
    53701 atatcttaaa acttcacttt gatttatgct tatatcttct cttccaatta aattattctc
    53761 catatatatt taaagaaaat cctttatcta aaacatcttt tgcatattcc tttgccccaa
    53821 ataaagataa gtctctgtag tttccacatt ctatagctgt agctgctggc attttatctg
    53881 attcaagaac tttttttaat gcttcttcta aaccaatctt aactgttttg gcatctacat
    53941 ctccccatag tattaaataa aatcctgttc tacatcccat tggagataag tctattacac
    54001 catctaatgt atctcttaaa taagtagcta aaagatgctc taaaccgtgc atagcagcag
    54061 ttccaaaact ttctacattt ggctgtaaaa atctcaagtc aaatttagtt actttatctc
    54121 cctttactcc atcaagtaca ctacactttc ttacaaaagg agcttttact tttgtatggt
    54181 ctagcttaaa actttctact ttttccatta tttaatcctc cattatactt taaaatttgt
    54241 tacattaatt ctaaaaaaaa ctcttcctat ctattattga taagaagagt atattatttc
    54301 aagtcatctc atcgttgtta gcaggaccac ctgataaaag gttggtatag gatcactgag
    54361 ctaactctct cccctaactc ttgataagta tcttattaaa ctgacttaaa ttatatatta
    54421 cttttttatt tttgtaaaca ctttattgtt ataatattta tatcacataa tcgtactttt
    54481 attttataac taagctgatt gtattattgg cagttgtact tcaaacacag tttgatattt
    54541 atcgcttgaa acagtaattt ctccatcatg taaatttaca atattttttg taatcgcaag
    54601 acccaatcca gaacctccaa catttctatt tctcgatttt tcaactctat aaaatctatc
    54661 aaatatattt ggtaaatcta acactggaat tggttcccca taatttatca cttttacaac
    54721 cgccatatct tcctttttct ctgtgactat atctacataa tgcccatctt ttccatattt
    54781 cacagcatta gttataagat tttcaaatgc tcttaccaat ttatttggat cagcttttac
    54841 aattaatttt tcttcattaa aattaattct actaaccata aattcttgtt taaaataaat
    54901 ttcaaattga gatactactt gacttaataa ctctactaaa tttatttcta ttttgtttaa
    54961 ttttattgta ttattttgca ttttagtcaa ttcaaacaaa tcatttataa gaacatttaa
    55021 atttttcgat ttttcatatg caatatcaac atagtacatc atctgaactt catctttata
    55081 cttaccttct tctatcactc ctaaataacc cattatggat gtcaaaggtg ttcttaagtc
    55141 atgtgacaca tttgttatta aatctgtttt tgtctgctga gcttgtctct cttcaatagt
    55201 tatatttcta agttgatgga ctatattatt gattttatgt gctagttcat caatatcatc
    55261 cttttcttta tcctttaata tatctaaatc atactcaata tctatacttt tttctaagtt
    55321 accttcatcc attaaattta cagcactttt aatgatttct aatttttgat tttttctatt
    55381 agtctttctt ataaaatcta caatttgctt atttctcttg tacgatataa tggaataaat
    55441 tgctaatgat gtgattgtaa ataaaaatgg ataaaataaa tcatacccta taagacttct
    55501 gaaatctctt gcttgatata caagttgatt aactacagac atatcactat tgacatataa
    55561 tgattttatt atatacatac ttgttaaaat aagcattgaa gttaaagcac agcttattat
    55621 aagatctaat atgggtcgaa acatatgatt taataaactt ttatttttca attttatatc
    55681 ctactcccca tacagtatga attatttttt ctccatctgt atatttttca attttatccc
    55741 ttattctgct catatgaacc attacagtat tattagattg gtaatatttc tctttccata
    55801 ccttttcaaa tatttcttct gtactatata ctctgccttt attatttgct agtaaatata
    55861 atatatcaaa ttctcttgat gtcaaaatta tttcatttcc agccactgtt acactatgtt
    55921 tttccttatc tataattact actccaacct ttatgacatc tttatcttca ttattagcac
    55981 cactaaaata atatgctctt ctaatcagcg acttcactct cacagtaagt tcaagtgggt
    56041 taaatggttt tgtcaaatag tcatctgcac cagtcattat cccttgtatt ttatccatgt
    56101 cttctgattt tgcacttaac ataagtattg gtatattcaa actttctcta acttttctac
    56161 aaacttctat cccatccatt ttaggcatca ttatatccaa tatcattaaa tgaatatttt
    56221 ccttttttaa aatatctaga gcctcttttc catcttcagc tttaattaca ttatatccac
    56281 tatttaaaag atatatctct ataaggtctc ttatttcctt ttcatcatcc acaacaagaa
    56341 ctgtattatt catttttaca catcctaact taatctttgt atatagcttt attcatataa
    56401 aattatacta tattttagtt agtgtaatct ataaatttat taatttctaa atttccaata
    56461 taatacaaat tatttacaca tttatattat ttattttgta aatattcttc taaagttaat
    56521 ccttttgaat aaatttcctc agcagcatcc ttaccaacat atctaatatg ccatggttca
    56581 tatgctgtac ctgttatatc ttctttacct tcaggatatc ttattataaa tccaaacttg
    56641 tgagcatttt ctgccaacca tttagcttct tttgtacttc caacaaacca tctttctgga
    56701 tttgttaaat caatacaaag tccagtttgg tgctcactgt aaccaggctt tgctacatat
    56761 gcatctgcct tttctcgccc ctgagatttt acccttcttg tataagtatc cagttgagta
    56821 tcataagatc tgtatgctga agaccctaaa aactgtattc cttctgaatt agcttgctta
    56881 actaaatctt caactgcctt tgcaggttct cctgccattt gtttttcttc ctctgttgct
    56941 tcttcaacaa aaggtatgtt taccttagta atattttcag gagtatagtt tttgctaatt
    57001 ccatttgtct tgtttaccaa taatatattt gatatactat ttgagtgatt tttattttga
    57061 gaatttgcct caacatcttg ttctgaatca tgttgagcag ctactattgg atctttatct
    57121 ttcttaagta atctatcttt agatataaat acacttataa atactactaa aataatggct
    57181 cctattaatt taaatttttt cataattaaa tcttctcctt tttgttatgt ttgctataat
    57241 gttaatttta gagtataaga cttaagtatt ttataagtaa atcttaaata aatcttaaat
    57301 ttaatatttt taaaggatgg tgataaaatg tctatacaaa aacttctaag taaagctcgt
    57361 aaggctatac aagattttga tatgatacaa gaaaatgata aaattgcggt tggactttct
    57421 ggtggaaaag atagtttaac tctacttcat atacttaaaa gttatcaaag attttctcca
    57481 caaaactttg aattgatagc cataacatta aatactggag gtgttgataa ttctccacta
    57541 gataaattgt gtaaagaaat aaatgttcct ttttatgaat ttcaaactga cataaaagaa
    57601 attgtatttg atataagaca agaaaagaat ccttgtgcat tgtgtgctaa tttaagaaga
    57661 ggtgctttga acgataatgc taaaaaactt ggatgtaata aagtagctct tggtcatcat
    57721 aaagatgatg caattgagac atttttaatg tctatgtttt atgagggtag agtaaattgt
    57781 ttttccccaa agacatacct agacagacag gatttaacag ttataagacc tatggtttac
    57841 atagaagagt atatgactaa gaaaatttca aaagattcta actatcctat tatcacaaat
    57901 ccctgccctg caaatggtca tactaggaga gagtacataa aaaatcttat tgctaattta
    57961 aataaagaga tgcctgattt taaaagaaat gtatttggtg ctttaaataa ttctgagaaa
    58021 ttgtttatat gggataaaga gaagataaaa aattttaaat aataattaaa atttttaaat
    58081 aaaaaagcaa gattgtatta attgtaaata atctttatat aatctacaca atcttacttt
    58141 tttatttatt atatgttatt atctttaatc tatattttaa tagttcttaa tagtatttat
    58201 tttgtctaat acattaatta taacttaaat attttatata ttaatttaat ctattaattc
    58261 attcaatcta ctggtttaat ccatttttac agtatataca tctacatatt ataaaaagca
    58321 aaattatatt ttctaaatat tttatgttag attataatat taaattctat tatctctggt
    58381 atattaaaaa atctaaatgg taactttgta cttccaagac ccgaactcac atataaatga
    58441 tttccattta tatcataaaa ccctttagta tatttccttc catatggagg agtaactaat
    58501 gctcccttaa taggtaatct tatttgacca ccatgactat gcccagatag aactaaattc
    58561 attgtatctt tactaagcat atctactaaa tctggttcat gtgctaacaa taaattaaaa
    58621 ttcttattat ctatttgact ctccagatat tttatattag gatttccatt taatatttca
    58681 tcaacaccta atatattaat atatttatca tcttttaatt ttattttttt attttcattt
    58741 actaaaagat tgaagttgga atttttcata atctgcctat aatacctagg aagtttatac
    58801 atataatcat gattgccaaa tactgaaaat tttcccaacc tagcattcat acttgataaa
    58861 atagttgtaa tttcatctac acttggattt ttattggagt aatcaattaa atcaccagta
    58921 aatactatta tatctggatt caaagtgtta atcttattag ctactttttt gagattctta
    58981 gttgaataaa aactacctat ttgagtatct gaaatttgaa ctacttttat cctttcagat
    59041 ttactctcaa ttgtatcact ttttatcaat gttccatttt cacttatatt atattttttc
    59101 acaattaata gactcggctc tatcgcaact gagtatataa aaatcaaaat aaatattaag
    59161 ataaaaaatt ttaaaaaata cttaattttt gagttcaaaa tatctaccta cttatttatt
    59221 tttttaaact atttgcatta cagactcaac tttgttcatt tttctgtcat gcatttttgg
    59281 cttatttgct gaaaaccatt tatatgttgc tgtaagacct tcttttagta acacatttgg
    59341 tatataaagc ccatgttcaa taagcttatt tatatcaaga ttaaagtcta tatttctaaa
    59401 tgggaaatac gttctttctc taaactctac tttttccata tctacatatt ttattatagg
    59461 ttctttgcca ataatttctc cacatgtata tataaggtca tcccaagaaa ttaactgtgg
    59521 atttgtcaca ttataggcct ctcttacatg aggatttttc attatgcttt ccaatacctt
    59581 taccaaatcc ccaatatata taaattgatt actaacttgt tttccttttg gtactggtat
    59641 cttttcattt ttttctattt tttcaaagaa ataatactct ctatataaat tattattttc
    59701 accatatata taagttggtc taataattat atatggtata gggctattta taataaaatc
    59761 ttcagcctct tttttattta acccatattt tccccagttt tcattttcac ctttctcatt
    59821 ttcttctttt atatttcttc cactatcttt atatactgct cctgctgaca atactatata
    59881 cttttttaag ttatccatac ttataaaatc aatcagatta cttacatctt cttttgtata
    59941 tgctgtcata tcatatatgt aatcatattt tcttcctgtg ataatgtttt ccatatcttt
    60001 tcgaactttt ctatcacaaa ttagatgttc tttaaaacca ttataatcta tttccttttt
    60061 accatttgta agtatatcaa tttgataccc acatttaatc aagcgcttag caagtgcaga
    60121 acctatgaag tcgcttccac ccataattaa aatagatttc attttaagtg catcctcctc
    60181 ttttttaaat gacttcctta actataatat catattttta aatatgcgac accattttgt
    60241 aatatttttg tctataaaag atatttataa caaaatatct tttatagact ctacattttc
    60301 gacaatataa gtaggttcac tttcactaag ttcttcaaaa gaaccatacc catacaacac
    60361 tccaatagaa tctataccta tttttttggc tccaattatg tcatactttc tatctccaac
    60421 cataataact ttatctttat cttttacatt acataggtct agtacatatt gtataacttc
    60481 atttttattc actcttgtac catcaagatt gctacctgct atatatttaa aatatctatc
    60541 tatatcaaaa tatctaagta tagtttctgc aaaaactgtt ggcttagaag ttgctactaa
    60601 taatatttta ccatttttat agagcatttc taatatctct tttatattct catagatttt
    60661 attttcaaat atccctttat cagcaaaata ttctctatac ttttcaacag cttctttagt
    60721 ttttttatct tcaaatttat aatactcctt aaaagtatca tgtaatggtg gtcctataaa
    60781 ttggtctaag ttttccaaat cttcttttat gccaaagcta tttaaagaat actgaataga
    60841 ctttgttatt ccttctttag ggtctgtaag tgttccatct aaatcgaata atactatttc
    60901 ataatttttt ttcatatttc agtcctccat atttgtaaaa agtaatatct tatatattaa
    60961 gtttatctat tttaaaaagc tatagtaata gaaatttcta atactatagc ttaagtaccc
    61021 aattaaatct tatatattta ttttaaaaat aaatttaaac agctctattt aactgttata
    61081 gctgaaactg gacatccttc ttcggcttct ttacataaat cttgtaagtc tgctggtatt
    61141 tctccttcaa ttgctactga atgcccttca tcgctcatac taaaaacgtc tggacatgtt
    61201 cctatacatg ctccacaagc tacacataca tccttatcaa caaatgcttt catactaaaa
    61261 tacctcccct aaaattatta ttttttaatt gttgtttcct tagatattta tccaatatat
    61321 accaatttaa acatatattt attattttat cactattgtt tagtttatta tagtattttc
    61381 gtatccatgt ctataaactt cactgctttt catccatgat tttacagtat attgcaatct
    61441 taatttttta tttaaaacaa gttcattatt attgtagtct tttataatat cattacactc
    61501 ctccattgtg aatattgtaa aatcaccttc tccaccaatc tttattctgc ctttatttcc
    61561 atgtaaatcg aaaatctttg ttgggtattc agttactttt tctatacact tttctaagga
    61621 tatcccaagt tccataattt tatttataac acttaaaaga gaatagttta cgtctttcat
    61681 gttttttata tgcatatcag tacttattag gtctggctct aaaccttgct ttattgcttt
    61741 tttaaaaact ttaaaatcaa attggttcaa tccatgacat acatcaaaca atactcctct
    61801 gttctttgca tttattactg attttcttaa tgtgccagat tctttaagga ttccatttgt
    61861 actatttcca tatactggtg taaccacatc tccttttccc aaaatattca ttacttcatc
    61921 tatatatgat ggatactctc ctatatatac cactaagggt aaatttaatt ttttggcaac
    61981 ttgctttgat ttcttaatta tatctatacc actttcatta gattgaaatt tactcgcttt
    62041 tacttttata ccctttatct tttctatatt tttttctaca actgactcaa ccttgtcaaa
    62101 atttataaca tctaaagaag ttgattcatt caatatattt agtccctcat ttgtaacatt
    62161 taaaaaagaa tatacttctg ttttacactc atccatatac ttttttttaa aatcatagta
    62221 gtttaaagga ccagctgtac ctgcatcaaa tataactgta gaaccttttt caattccaat
    62281 tgaatcagaa tccatacctg taggtaattt tctcttataa caatgggtgt gaacatctat
    62341 aaatcctggg gaaatataca tattatcggc atttattatc tcgaactctt tatttgtaag
    62401 taatttttct tttcttattt tctctttaag gttcaatcca atagcatata ttttcccatg
    62461 taaaaccaag atatctcttt tttcaaattt gataccatct gttggagata ttattgtccc
    62521 atttcttata agcaaatttt tcatttattc cacatcctaa ttacaatata atttctctaa
    62581 tagcttttct tacataaaga aaataagcct aaaaataaaa atattttaga cttattcact
    62641 atattatact atattaatta tattaaatta aataaaatct ttaatttact ttaagaagca
    62701 attaagtatc tgttgttcgg cttcttcttc agtaagacct aatgtcatca tctttagtat
    62761 ttgatctcct gcaatctttc caatagctgc ttcatgtact aaaagagcat ctggatgatt
    62821 tgcagcaatt tcaggtatag cactaatttg agaatttccc ataattattg aatcacattg
    62881 aacatgtgca gaacaaaggg aatccccaat aacacaagga ttaaactttt gcttagaatt
    62941 atcttgccca actgtacgag aaactacttg agcagaagag ttttccccct ctaagataac
    63001 cttcatatta gattctgcaa cttgattacc atgagttaat aatttctcaa atacaactat
    63061 tttagctcct ttacctaggt ttgcatccat ttctctttta gttgaatcta cacccttaat
    63121 ttgaattgtt tccatttcac aatatgaatc ctcatccata ttgacaatag taactggatt
    63181 taaaattctc tttccttctc catcaccttc accataatgt ttttctacat attttaggcg
    63241 agctccttta cgtaagaaaa atctatgtat accattatgt tcactatcat cacaaccaca
    63301 gttatgtata ccacacccag caattataac aacatctgca ttttctccaa tttcaaaatc
    63361 attatatacc atatcctgta caccagtctc tgttactatt actggtatat gtacattttc
    63421 tccttttgta tttggcttta ctataatatc tattccaggt ttatcagttt taggaattat
    63481 agttacattt tcagttgaat gtctctctac tccttgccca tttttacgta tattgtatgc
    63541 tcctaatgga gttccacgaa gttcagcaac tttttctaaa agatttaaat ctattttgtt
    63601 catttaattt gccttccttt ctaattaatt catgtctttc at
//
LOCUS       DAJMZY010000007        62434 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.007, whole genome shotgun sequence.
ACCESSION   DAJMZY010000007 DAJMZY010000000
VERSION     DAJMZY010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 62434)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 62434)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..62434
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.007"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            219..1067
                     /locus_tag="OE968_000434"
     CDS             219..1067
                     /locus_tag="OE968_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HCP7217751.1"
                     /translation="MNNQKNLNIPITISSYTLGTEVSFRDRVRIAKEAGFDGIGLRAE
                     NYIDAKNAGVTDEEMIAILNEYDMKVTEVEYITQWGREEDRTEAQREKEQNVYHMAHL
                     FNVKHINCGLLEMIPEEQIITALGELCDRAGELIIGLEFMPYSGVPDLATAWRVVKGC
                     NRENAMLILDTWHWARAKQTAEDLAPVPADKIVSIQVCDVLETPYEKLRDESLHDRLA
                     PGEGYGNTEEFVKIIKEHNISPRVIGAEVISDSLISKGLSTAAETVFNATKKVLDKAW
                     SEVSPK"
     gene            1131..3053
                     /locus_tag="OE968_000435"
     CDS             1131..3053
                     /locus_tag="OE968_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HCP7217752.1"
                     /translation="MKISSMFTPIRIGSMTVPNRFVVPPMGNNFANTDGTLSETSKAY
                     YLERALGGFGLITIESSVVDKKAKGGPRKPCLYDDSTIDSFKNVIDACHDAGSKVSIQ
                     LQHAGSEGNEKVAGHPLKAASAIPASNGRNTPLAITTEEIYELIESYGDAALRAQKAG
                     ADAVEVHCAHGYLVSSFISQRTNKRVDEFGGCFENRMRLPRLIIENIRKKVGNSLAIL
                     CRINSTDDVPGGIDVHDSSVIAAYLEDCGIDGLHVSRSIHIHDEYMWAPTTLHAGFSA
                     ELVTEIKKAVSIPVITVGRYTEPQFAELMVRQGRCDLVAFGRQSLADPEMPNKAKNGK
                     LDEMIPCIACLQGCVPNMFQGKPIACLANPILGHEAELKPAEISKEVLVVGGGVGGML
                     AAWVCAKRGHNVTLVEKSEVLGGQMRLAAYPPGKGDITNLVRSYISKCNQYGVKICTN
                     TEATVELIKEKSPDVVIIATGATPLVLPIPGINDSGLIHAVDLLDGKKSCGKKVLVVG
                     GGMVGCEVAAFLGEQEHEVTVIELREEVGADVISEHRKFLMNDFENYNIHTITGAKVS
                     KFYDDGVDYLLTDGTEHDLKGFDSVVLAMGSRNYDPLSEVIKEVVKETYIVGDAVKAR
                     RALDATKEAFEVALNI"
     gene            3135..3998
                     /gene="aroE"
                     /locus_tag="OE968_000436"
     CDS             3135..3998
                     /gene="aroE"
                     /locus_tag="OE968_000436"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HCP7217753.1"
                     /translation="MEISGRTGLFALIGTPVGHSKSPVMYNYSFKKLDLDYRYLAFDI
                     TVDKVKEALLAIKTFNIKGANVTMPCKSAVTEYMDELSPAARIIGACNTIVNDNGKLV
                     GHITDGVGYVRNLKENGVEVKGKKITIMGAGGAATAIQVQCALDGAREISIFNPKDDF
                     YKRAEQTVENIKKDVPECVVNLYDLEDTNKLYEEIQSSDILTNATLIGMKPYDNETNI
                     KDTSVLRKDLVVTDVVYNPKKTKMIEDAEANGCKAIGGLGMLLYQGAEAFNLYTGLEM
                     PVEEVNELCFK"
     gene            4198..5415
                     /locus_tag="OE968_000437"
     CDS             4198..5415
                     /locus_tag="OE968_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCP7217754.1"
                     /translation="MNNKKYYPTAIALYFSYFLLGIGISILGQYKPEFSSMWGAKTLS
                     DGTLDVSIVLAVIAALGLGRLISYPFAGPISDKYGRKVSGLIGNFLHAIFFVGIVFSP
                     NFYIAYVFAIIGGAANSFLDTCVTPSCMEIFASLGTIANMFTKFTIALAQFLLPFIIG
                     FVAANSISFKVIFIVTAILIVVDAFLIAVLPFPPANNVIDNKGKTVKSEKMKFTPTSI
                     ALVCIGFTCTSTFVLWLNCNQELGKLYGMADPTKIQSFYSMGVICAVLITSLLIKKYI
                     KPIRILVIYPIIALLMLLVVYFVQTPTICMLGGFVIGYSAAGGVLQLTTSTANEMFPT
                     NKGKITSIVMIASSIANYVILNIAGIITKSGGVNGPKYVVLFNVAITFVGILLALFVN
                     MRYEKEKVYDYDV"
     gene            5651..7516
                     /locus_tag="OE968_000438"
     CDS             5651..7516
                     /locus_tag="OE968_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIRAN domain-containing protein"
                     /protein_id="HCP7217755.1"
                     /translation="MENVFKRLQEFNGYDGYKESFEMNYLCIYESIPLREQVELANNL
                     VDEILNMYKSESNEIYLLEGSNSKSLICYFEIFMKKINTLVKEMIIDEKWLYKLTKEL
                     IYKSKKVEYVKLGLVLSEKYLNVENLREVVDTFSKSGEYVFYLSNTIKKLEFYNTYLF
                     NLSKKATGSIKVFAIVNMENLDSKINSYLIEDGYKDTKYERLLMNYIISIVDLNEYLE
                     KRDLDKEKINNLARLICNYLLSVEFKYIGNKLELVNRFLPTVVNYGTNFESLYSIFLI
                     AINVLKDENIECNKIEFEKEINGILLSEKWKNIYFEALRDASGKTEDIIKMSEIYDVN
                     LSFDDLLPYLNRDIRDFEVYWHISKKGTTSSRLKLLNFFEETFKIDDLIGKMKDIEKD
                     KLTQEYYDDMLFFIVLKGSKSLYPEGKNISLKGIFGNINEVRKESINILKRYREKLSL
                     EELKIVKEAYEKEKNVILKDELRRVLYESNNLKKEFVNIEKIKVDEHGKDIYLTSIAV
                     AGSRFRNREYLEKELEKSKIYYLTREKDNLYDEKAIKIVGETGYVIGYVPRKENYILS
                     NLLDGGKLLYCRVTEYNLYEDCIYANVYLSYKDVIETVENSLKMVLDKSRIKLIN"
     gene            complement(7694..9058)
                     /locus_tag="OE968_000439"
     CDS             complement(7694..9058)
                     /locus_tag="OE968_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HCP7217756.1"
                     /translation="MSQLLIKNAYLITMNADREVYENGSILIENNIIKEVGKFDINIV
                     DKDAEIYDAKGKILMPGLVNTHVHLSQQLGRGLADDVVLLTWLRERIWPYESSFNYED
                     SLISSTACCVELIKSGVTTFLESGGQYVDAMVEAVDKTGLRACLAKSVMDTGDGLPEA
                     WQKTTDEEINTQLDLFHKFNNTSNERIKIWFALRTIFNTTEELLVRTKELADKYNTGI
                     HMHIAEIADEISFVKQNNGVGTVEYLDKLGVLGPNLLAAHTVWLTHKEIDLFRLHDVK
                     VSHDPGSAMKVVLGFASIPEMLEKGIPVSIGTDGAPSNNRMDLMRDMYLTSLIHKGRT
                     LNPTVVPAEEVLEMATINGAKCALLEKEIGSLEVGKKADMIILNPDTIHCLPMHNPIG
                     NIVYSMTSENVDSTICDGKWLMKERKVLVVDESELLNKVKKQASKIKDKAEVKIPSKF
                     KIIK"
     gene            complement(9237..10580)
                     /locus_tag="OE968_000440"
     CDS             complement(9237..10580)
                     /locus_tag="OE968_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HCP7217757.1"
                     /translation="MVPNTNNVQPGGNNSSLSFLDKMFKFSERGSSLKTEVIGGVTTF
                     LTMAYIVFVNPAILSEAGMDKAALITVTILATAIGTLIFAILGNAPFALAPGMGLNAF
                     FTYSLVIGAGIPWQTGLGVVFLSGCVFFTLAVTGLRKTIADAIPRELAVASSAGIGLF
                     LAFVGLKNMGVIIANPDTIVSLADFTPTVLIALFALILMAILEYKKVKGGILISIVVA
                     TIISVIFGFVELPTAIISTPPSIAPVAFKLDIVGALKFSLIGPIFSFMFIDMFDSLAF
                     LITCCKQMGLEDENGEIKDLGRMLYADVSSTLIGSFLGTSTVTTFGESASGIAAGART
                     GLASIVTAALFLATLIFTPLLGIVPTYAAAPALVMVGVFMFESIKQIDFADSKIAVPA
                     FVTVLLMPLTYSISIGLCFGFISYIIMHVVAKETDKISITLWIIGLLAVVNLVLS"
     regulatory      complement(10653..10754)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            11083..11736
                     /locus_tag="OE968_000441"
     CDS             11083..11736
                     /locus_tag="OE968_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HCP7217758.1"
                     /translation="MTKIIKVQKPKFTGELEIIENLEDILEDIFNDEKIFNKIIENEV
                     ISDLDSVRVSFESCIFRNVSFENCNLKKIDLLDVVFENCNLSNTFFDGGSIYRVEFKN
                     SKLIGVRFDDCILKNVLFKDVLGKYSNFSFSKFKIVSILDSNFENSVFQEVKGDNLVF
                     EYTNLKKANFNGTKLSGIDFTTNNIEGIEIGIDDIRGAIFDVSQAIDLTKLMGIIIK"
     gene            11877..13148
                     /gene="brnQ"
                     /locus_tag="OE968_000442"
     CDS             11877..13148
                     /gene="brnQ"
                     /locus_tag="OE968_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HCP7217759.1"
                     /translation="MRDIFIVGFALFSMFFGAGNLMFPPFLGMESGKDWLIPLIGFVV
                     ADAGIAMLVIIATARCKGSMDDVLRRAGKGLARVMSVAALACLALLVIPRTCATTYEM
                     GIMPIFGDHGPVAKAVFSIIFFGLTLAFTIRSSKVIDIIGKYLTPALLLVLFVLIVKG
                     IISPAGPMSPEHMIDKNLFGEGISQGYQTMDALGAASMATIMLMSIIAKGYTSDKDQI
                     GMTIKAGFVACVFLAVVYGGLTYLGATVSTLYDTSIPQASLLVEITSILLYGQVGKVI
                     LGVIVALACLTTSTGLTASISTYFEGISKASYKQLVIGICVASMLISNLGVDSIIAIS
                     VPILQTIYPVLLAIVVMELAGKHIKNDNAFKGAAYVTLVISLLSAINGMTGAVPFIQS
                     LPLAGLGFNWVIPAILGGIVGNFIKSNKQVA"
     gene            13350..14537
                     /locus_tag="OE968_000443"
     CDS             13350..14537
                     /locus_tag="OE968_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3798 domain-containing protein"
                     /protein_id="HCP7217760.1"
                     /translation="MLRKITAFMLSICLIIGLTGCSLLVGKKDKEKIIDDFKVAVVTQ
                     PLSENKVQYNMVEEMAKEYEEENKIDKDKDGQTKVKQTIKHVVLPENFTSNIDSAINK
                     IVKLADDKEVQAIVVSTDQAGLLPALQKVKEKRPEIITISAPMGDDKNQLSQFVDVNL
                     GVSAEERGKVLAERSKEMGAKAFIHYASTDDLKDVNIAKRLEMIKETCKNIGLPFVQV
                     NTPNINTEEDKNKVKQFLNEDIEKQVKKYGKDINVFGVNEYMDEVILTKALELKYIVA
                     EQSNPSPIQTYPSVMGLKISEKDAQNYDKINDMISEKAKAFGMSNRLGGYPMPMDAFL
                     PSVAIYLATEMVKQDLTQEDVCDPDYLEAFTELRFGIGSEFTPLTEVLYNYQSVILSQ
                     LIY"
     gene            complement(14767..16791)
                     /locus_tag="OE968_000444"
     CDS             complement(14767..16791)
                     /locus_tag="OE968_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HCP7217761.1"
                     /translation="MDKKKLILITHDKLNSDHYKEELTNFFGDEIIIETQNILDGIKE
                     NLEGDVVLSLSPLTSNFLIKHFKEDIEIIHGTKALSKLGYEKMMKLPPGTKSLLMTTN
                     KTSAFEMATYLYKIGINHIDFVPTYPDCDEIYDLDTAITPGQIRFIPKYIKNIVDLGW
                     RKISLDTYMSLLVVLKLKNEKFIEKLYKLSKETLSHDFLNTSLDNISKLKTILYMTID
                     EIGDGLIFFNTFNKVTFVNKSLLNMLGLDEKLIKSPSLMEYMPNSFLDKITKNLNIDN
                     MIIYIDEIDKKFILSKKPFYLYKNIEGCLITLKDVNNIEILEQKIRSDSVKRGYVAKY
                     KFNNIIGNSSIIKDCIKKAKKMALTDNPILITGETGTGKEAFTQSIHNHSNRKNKPFV
                     AINCASLPSELLESELFGYEDGSFTGAKKGGKKGLFELAHTGTIFLDEIGDMPHDLQV
                     KLLRVLQEKEIRKIGGTSIIPIDVRILAATNKDLEKLIIENKFRMDLFYRISMFTLDL
                     PPLRKRLEDIPLLLESFLKELPYKNIKLDKSLLEALNSYTWMGNIRELRNCIEYMAYM
                     GSNYLTINDLPQNISSKLNNNHMSSNMSIFNDLNQYDKNICISILKSLHMKPMGRTKL
                     MKFMEYNVTEYEVRNMLEYLTRNGYLISSKGRKGSSITEKGIKIIENNII"
     gene            17181..17849
                     /locus_tag="OE968_000445"
     CDS             17181..17849
                     /locus_tag="OE968_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7217762.1"
                     /translation="MSKLESTTEKVEVKWYGYVALILGALFFSGIFKDAPGPLKVLDF
                     NNVLGSFGTLGTINDGVGTLAANFRGDGGTGPRDGWLYALTLIPSVMFALGVVRVIDH
                     LDGMKAAQKLLSPLLKPLLGLPGFAGLTLIASLQSTDAAASMTKELKDDGYIDEKQKA
                     VFCAFQFSGASAITNFFASGAALFPFIGDVPIFIPLALILIMKFVGANLLRLYLNKFD
                     KGEA"
     gene            17851..18336
                     /locus_tag="OE968_000446"
     CDS             17851..18336
                     /locus_tag="OE968_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjiG family protein"
                     /protein_id="HCP7217763.1"
                     /translation="MSEVAKKEVKVKKGNVIDAFIGGARNGFQISTNSMAPNVIFGFA
                     IISVFNLTGLLDVIGTIFTPVMSIFGLPGVAATAIMTIFISMGGASGVIAGLFTAGQI
                     SQAHVAILLPMLLLSGAQIQFMGRLLGTAELKTKYYPHMFVIATLNGCIAMLIMNYFV
                     V"
     gene            18397..19518
                     /locus_tag="OE968_000447"
     CDS             18397..19518
                     /locus_tag="OE968_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 peptidase aminoacylase family protein"
                     /protein_id="HCP7217764.1"
                     /translation="METNKDYIEYVHKVYDYLHTIPEKGFEEYKTSEFVLKELEKMGF
                     ENINKGIAGTGIIVTIDSKKEGPVFAIRADMDALEFIIDGEKKMIHACGHDGHTSMLL
                     TAAKLIKERNLVKRGKLKILFQPGEEKLYGALRVIDSGLLDDVEEMVGMHLRPGQDCR
                     LGKAIPAMYHCASCIMEFTIKGITCHGSKPHLGVNAVDAVCLAVNAINAIRVNPAIPN
                     SIKVTNISVKGETYNNIPDEAFMALDIRAESNDIIEELKEKAIHAVKTAVSSINAEAV
                     LISKDGVPAAEFDEELVNLAEETIKDVLGADASIGIFKNSGGEDFHYYTQKLKCKTTY
                     IGLGADATPGFHNPNVTFDTKALEYGVDIWCRLVEKRLG"
     gene            19799..20989
                     /locus_tag="OE968_000448"
     CDS             19799..20989
                     /locus_tag="OE968_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HCP7217765.1"
                     /translation="MSKYNFDRVIDRVGTDCVKWDFRTNCSTKAQKDGLPFWIADMDF
                     ECAEPIIEALRKKVEHKIFGYSSNDSDKYFNAVCDWYKRRFNWEINRKDIIFSPGVVP
                     AVAILVRILTNSNEGVIVQKPVYYPFEAKIKSNNRDVVNNPLIYENGTYRMDYDDLEE
                     KAKCSNNKVLILCSPHNPVGRVWREDELKKVVEICKKYDLWIIADEIHSDLIRKGFKH
                     TPLQSLCPEYKDKIVTCIAPSKTFNLAGMQLSNIIVNNDELKKKYQEEVTAVGVATSP
                     NPFAIVATIAAYNESEDWLNELNDYLDNNIQFIDEYLKENLPKVKLVYPEGTYLAWLD
                     FTAYGLNEVELEDLMFKKANVLFDEGYIFGKEGIGFERINVACPQSLLKECMDRLKTI
                     FENL"
     misc_binding    21123..21378
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            21437..22438
                     /locus_tag="OE968_000449"
     CDS             21437..22438
                     /locus_tag="OE968_000449"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HCP7217766.1"
                     /translation="MSTIIPKDYKSSLNVIDTQIAIKKLKDFFEMRLSNELNLIRVSS
                     PLFVLPETGANDNLNGEKAVSFDIPFMNKNAEIVQSLAKWKRLALKKYGFEVGSGLYT
                     DMNAIRKNEELDNIHSLYVDQWDWELVIDKSSRNEKTLKDVVKRLYGVFKDTEIFVCS
                     MYEGIKEILPEEITFITSQELEDMYPELSPKEREDKIVKEKKAVFITQIGKTLISGEK
                     HDGRSPDYDDWELNGDILFYNPVLDSALELSSMGIRVDEESLDRQLKLAGCEERKEFD
                     YHKMLLNGELPYTIGGGIGQSRICMYFLQKAHIGEVQVGVWPQDMIQNCSSAGIELL"
     gene            22542..22931
                     /locus_tag="OE968_000450"
     CDS             22542..22931
                     /locus_tag="OE968_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1232 domain-containing protein"
                     /protein_id="HCP7217767.1"
                     /translation="MEFLKIIINIVLDILKKILVRFKNAKFGLVFVFDLLKLPDFMTD
                     KRINIVDKIKVISVLIFTISYFVSGVDIIPEMIAGAFGFIDDAIVLIWSIGIVNEEIN
                     KYRVIAKKDKHSNIIENVEFSIKDEEE"
     gene            23092..24300
                     /locus_tag="OE968_000451"
     CDS             23092..24300
                     /locus_tag="OE968_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dicarboxylate/amino acid:cation symporter"
                     /protein_id="HCP7217768.1"
                     /translation="MKKKIGLVPKLIIGIIVGILIGSYAPEIIVQILVTVSTLFSAFL
                     KFVIPFIIIGFVTAGIADLATGAGKLLGITTGIAYGSTLIAGLLSFAVSTLIFPNFID
                     ASVASQIGDPEAGMLAPIFTIPLEPMVDVTAAIVFAFVMGLGISALRNHGKGETLFNF
                     FQEFQGIVTKTLSTVIIPLLPLYIAGTFANITIAGEVWTILGVFWKVYLVVIPLHFVY
                     MACQFTAAGVFSGKNPVRMLKNQVPGYLTAIGTQSSAATIPVNVGCAEKNGVSKQIRE
                     FVVPLCATIHLSGSMISITGFTTAVLMMNGMPHGIGVLFPYIAMLGIAMVAAPGAPGG
                     AIMSALPFLPMVGIPSDGGLASLMIALYLTQDSFGTACNVSGDNAIAVVVDKINDGMS
                     KKGNKEEQSA"
     gene            complement(24386..25462)
                     /locus_tag="OE968_000452"
     CDS             complement(24386..25462)
                     /locus_tag="OE968_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003415975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HCP7217769.1"
                     /translation="MSTNHGANLYSLSSKYGFSKEEFMDFSSNINPFGTSSLAKQYIV
                     NNIDMVSMYPDPDYIDLKTSISNYCKCSIDNIVLGSGATELISSFIHTINPKQALLLS
                     PAYSEYEKELSKINCSIEKYFAKEEDNFHINLENLIKTINAKDYDLVVICNPSNPTGF
                     AFTKVEVREILKNTDSFLMIDETYVEFTDTDTYSCTQLVDDYSNLFVIRGTSKFFSTP
                     GIRLGYGLISNTNVKNEINKNLDLWNINIIASKMGEIMFSDLDFISNTISLMNTERDY
                     LLKELKNIKSLDIYNTKGNFILCKIKTKELTAKSLREQLLPQKIIIRDCCSFEGLDEY
                     FFRVCILKPNENKLLISSLKAIFK"
     gene            25691..26218
                     /gene="hpt"
                     /locus_tag="OE968_000453"
     CDS             25691..26218
                     /gene="hpt"
                     /locus_tag="OE968_000453"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HCP7217770.1"
                     /translation="MYKVTGKMLTEEQIKEKVYELGKKIEEDFKGEDLLVVGILKGAS
                     VFVSDLIRCIDLDVNIDFMSVTSYGNSTESSGTVKILKDLDVDIEGKNVLIVEDIIDS
                     GLTLSNLVAALKTRNPKSLKLCTLLDKPQRRKANIPVDYVGFVIEDKFIVGYGIDYAE
                     KYRNLPYIGIVEDVE"
     gene            26307..27239
                     /locus_tag="OE968_000454"
     CDS             26307..27239
                     /locus_tag="OE968_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HCP7217771.1"
                     /translation="MDIQLNILLFFQNLRNPILNFIFLVFTISTEAPLLILITTIIYW
                     CINKKCGQKILFAIIGNFVVNLGIKEFVKAPRPIGIKGLESLRVSTAGGYSFPSAHTQ
                     TATTFWVSIMTIFKKRYLHLIGAVMVLGVGLSRLYLAVHWPIDVIAGWILGIFFTVVF
                     VKIFDYIDDNKNYILLVVLLIPFIIVAIFLNSPEYFEKFGIIVGFVFGYMVEDRFVKF
                     NTDNNNKKINFSNKNKGSKNIIFSRICRFLVGIVTIGMLYIGIKLFISMLIVTLNISD
                     STMSIIFMNFIKNTVVVFYGIAGAPALFKLLKLN"
     gene            27301..28527
                     /locus_tag="OE968_000455"
     CDS             27301..28527
                     /locus_tag="OE968_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HCP7217772.1"
                     /translation="MKKVVIIGGGPAGMIAASTACEKGYDVTLIEKNHKLGKKLAITG
                     KGRCNITNACEIEELIENVPTNGKFLYSAFYTFTNDDVISMFNNLGVKTKTERGKRVF
                     PESDKAFDIVNALERQLKSKKVNILLNSKVEKIISKNNKIEKVILNDKKEIKCDSVVV
                     ATGGLSYPLTGSTGDGYKFAISQGHTIIDTKPSLIGIEVQESFTKDLEKLSLRNVEIR
                     VFNSKQKKVYSDFGELEFTKFGLDGPIIKSASCRMKDTRKENYTILLDLKPALDEEKL
                     DKRVQKDFQKYTNKKFEKALDDLLPKKLIPIIINLSEINPNTVVHQISREQRKNLVHL
                     LKNLKFTVKRYRPIEEAIITSGGVKVNEINSSTMESKLVEGLFFAGEVIDIDAYTGGF
                     NLQIAFSTGYLAGFNC"
     gene            28611..28832
                     /locus_tag="OE968_000456"
     CDS             28611..28832
                     /locus_tag="OE968_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000002841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta-type small acid-soluble spore
                     protein"
                     /protein_id="HCP7217773.1"
                     /translation="MASNNNNNRTVVPGAKEALNQMKLEIANELGMSNYQQVDKGNLT
                     ARENGYVGGYMTKKLVEMAEQQMAGKSNR"
     gene            29021..29191
                     /locus_tag="OE968_000457"
     CDS             29021..29191
                     /locus_tag="OE968_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7217774.1"
                     /translation="MSSVNFEDLKNKFINSDLDEKIRIYTTTEGLSVEQFKELLKYYP
                     IQHLSKLEKALG"
     gene            complement(29284..29745)
                     /locus_tag="OE968_000458"
     CDS             complement(29284..29745)
                     /locus_tag="OE968_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7217775.1"
                     /translation="MQIEQLDLETRNKIYCYTKKILRKYQKGITSGKLTADKFADNIL
                     SQDFISSILNEKIVNETNFKISYRNYIETLINIQNENLSNLRKKSTKTAKCFNISQIT
                     QLKNLLSNTGYNLLIPYKYLTARDIEGIVTLINTGSIELGNERIYNYISKA"
     gene            29928..30395
                     /locus_tag="OE968_000459"
     CDS             29928..30395
                     /locus_tag="OE968_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7217776.1"
                     /translation="MKMLNGIIKLFYSEIVKTKINNLDSSGYSLRDECKEIRNITLKI
                     DSVFFKLLKLAFGSILLMVAFNLNMVLGIGVFLVGVVYILYKRNMEEQVKEHINNVKN
                     NIDISKITFMDEKGRTGLNALITLLLIGLLTGFNWILVASFVVVFVFTIKNVC"
     gene            30438..32201
                     /locus_tag="OE968_000460"
     CDS             30438..32201
                     /locus_tag="OE968_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpoIIE family protein phosphatase"
                     /protein_id="HCP7217777.1"
                     /translation="MTNGSYKMKNLVEISAMVTESTDFFNIKDDIIEKMLEVVHPTKA
                     CVNLFYKNDSKYAYLVCSQTLEYVPQIFPINSLKGAKIDFDTYPEYIHEAVNEKKIIY
                     VENVFEDSRAEGERDLAKAEGYIGRIVFPFIINNVVVGFMTCFLKEDDYITEQDIDFI
                     SSVASLLSLSIEITNKNNNVQILIDKLRGSISAINEATKKLYLNKSIDGFLENLSKQA
                     CNITNSKEALIIINSHHNKDAIVSCYNVEQKKKTNLYPMIDMFLKKESLGGYLNNLKP
                     CSKKGINLESYIYYKLQDKNETIGCIVCANSKNYTSDDLNILSILSKQVSVGMQLYEH
                     NEKEVKHKVLENELNILNKQQQLIMDKGKMDCNDEKELYFYHKPARVVGGDFYYATKV
                     DDEHIVYIVADVMGHGMVSNYVVAMIKGAFKVLCNQYNTPREIMTNLNRMLYDEFDKM
                     GVFTTCLIGIIDTKENMITVSNAGHYSPVVVKKDGTIENNLNCKKGIPIGIMEDATYE
                     NNTLSMEDYAMVCMYTDGILEIKNSSKEEYGINRLENFLKENFRLNQQLIVENLKLDL
                     KNFSSKDNYDDDILIVMLKDR"
     gene            32209..32817
                     /locus_tag="OE968_000461"
     CDS             32209..32817
                     /locus_tag="OE968_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HCP7217778.1"
                     /translation="MDSNDKKGLKSPEIIIINGSPRINKNCSFIANEVKAMLEECGLS
                     CKIFNIYNMDIEYCTACGFCEKTGYCKFNDDMKPLYKMFDDSKGTIVISPVHFDSISA
                     KLKTVVDRTQAIYASKYVLNKPSIDRSKKRIGMYIAVGGSKSYDSQFKGGQIVMDFFF
                     KSINTKLLHNIYLNNTDDVSYIDNQEFKDIIYKNLKIYIDSI"
     gene            32889..33458
                     /locus_tag="OE968_000462"
     CDS             32889..33458
                     /locus_tag="OE968_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate propanoyltransferase"
                     /protein_id="HCP7217779.1"
                     /translation="MKLPIALSNKHVHLSQADIDVLFGAGHELTKFKPLSQPGQYACE
                     EKVDLVGPKGTLKGVRVLGPARAHTQVEISLADGFPLGVKAPIKESGDIAGTPGVKLV
                     GPAGEVEMKEGVIVASRHIHMSNEDAAKFGVTDKQIVKVKTSGPRALVFENVLVRASD
                     SFNLEMHVDMEEGNAAGVKNGDLVELIVD"
     gene            33976..37515
                     /gene="nifJ"
                     /locus_tag="OE968_000463"
     CDS             33976..37515
                     /gene="nifJ"
                     /locus_tag="OE968_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HCP7217780.1"
                     /translation="MAKFMKTLDGNTAAAHVAYAFTDVAAIYPITPSSTMAEVVDEWA
                     SQGRKNIFGQTVNVVEMQSEAGASGTFHGSLQGGALTSTFTASQGLLLMIPNMYKVAG
                     ELLPGVFHVSARALASQALSIFGDHQDVMAARQTGCVLLASGSVQEVADIAPVAHLAA
                     IEGRLPFIHFFDGFRTSHEIQKVELLENEDYASLLNFEAVQAFRDNALSPNHPVARGT
                     AQNPDIYFQTREASNKYYQNIVGIVEKYMEKMSNLTGRKHSLFDYYGAEDAKYVLIAM
                     GSVTETIEETIDYLNAKGEKYGLVKVHLYRPFSMKHFLDAMPSTVERICVLDRTKEPG
                     STGEPLYLDVRDVFYGKENAPMIIGGRYGLGSKDTTPSDIKTVFDNLVSEQPKNGFTV
                     GIVDDVTNTSLTPSEPIKIASKGTIRCKFWGLGSDGTVGANKQAIKIIGDHTEKYAQA
                     YFDYDSKKSGGITMSHLRFGDTPIRATYLIDEADYIACHKQSYVYQYDLLKGLKKGGT
                     FVLNTIWDQAGLEEHLPAHMKQYIAKNDIKFYTVNAVKLGQEIGLGNRINMIMQSAFF
                     KLAEIIPEEDAVKYLKDSIVKAYGKKGEKIVNMNYAAVDAGINALVKVEVPASWENAV
                     DADKGEVKEPEFIKNILRPMTAQEGNNLPVSTFNGIEDGTFPCGTAAYEKRGIAVDVP
                     EWIIDNCIQCNQCSFICPHSCIRPVLVTEEELANAPEGFEAKKALGKGLEGLKYRMQL
                     SPLDCTGCGNCADICPAKEKALVMKPIDTQLDTELDNWAFAVNPDEVAPKGDVMPANT
                     VKGSQFRQPLMEFSGACAGCGETAYIKVVTQLYGDRMMIANATGCSSIWGASAPSIPY
                     TCNHEGKGPSWANSLFEDNAEYGFGMYTAVKQIRNKIVDAMTELVSMDICEDAKAVFT
                     EWLDSRNDGEASKVASAKVVELLEKPACDCTDEKAKELVKAIKDRKDYLVKRSQWILG
                     GDGWAYDIGYGGLDHVLASGEDVNVLVFDTEVYSNTGGQASKATPAAAMAKFAASGKK
                     SRKKDLGMMAMTYGNVYVAQVAMGADKNQFIKAVIEAEKHDGPSLIIAYAPCINHGLK
                     EGMGRTVANEAQAVACGYWHLYRFNPEVKAEGKNPFTLDSKEPTASFKDFILAQVRYS
                     AIAKQFPEEADGLFAKAEADAKERYEGYKKLAE"
     gene            complement(37907..38803)
                     /locus_tag="OE968_000464"
     CDS             complement(37907..38803)
                     /locus_tag="OE968_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein"
                     /protein_id="HCP7217781.1"
                     /translation="MMRRNIPTKLKTILALGVLTLATASSAVTASASSLENNVNISNK
                     SLVYSNTKYKFSAKPNCSVKPELKPDKDNSCKDKNHNDKNCNNTNKPEDNNNSDSTNK
                     PGNNKPESNKPEDNNNSGSTNKPDNNKPESNKPEDNNNSGSTDKPEDNNNSDSTNKPD
                     DNNNSGSTSESFSAYQKEVVDLVNIERAKAGLNPLTLDSSISNVATKKSQDMIDNNYF
                     SHNSPTYGSPFDMLKKFGISYKTAGENIAMGQKTPKEVVNAWMNSEGHRKNIMNPNFS
                     KIGVGVAQKSGGSIYWTQIFVG"
     gene            complement(39299..40633)
                     /locus_tag="OE968_000465"
     CDS             complement(39299..40633)
                     /locus_tag="OE968_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HCP7217782.1"
                     /translation="MSIIAPIGIIIGIIAIIYFSVKEIHITIAAPIATLIVVILNKMD
                     VVTSMLGADKNNYMGALGNYIMSYFAIFLLGSILAKFMEESGATVSIADFILNKFGSN
                     HPYRVLVAIFIVSFILTYGGISLFVVMFAVIPLARTLFKKLDISWNLIQIPLWLGIAT
                     ITMTIIPGTPAIQNVIPIQYLNTSLTAATIPSIVGSIGCATFGLVYMKYALNKSIRKG
                     ETYATYTSELEEESLDRELPGFFASIFPLLALVIIAITGSTFGSEFMKKNVIYIALIV
                     AILLSAFLFHKFLSSKIQTLSIGASGSIGPIFATSSAVAFGAVIMAAPGFDVFSKLIM
                     SIPGSPLISLTVLTSTMSAITGSSSGALGIVMPNFADYYLSTGLNPELIHRVATIASN
                     ILTIVPQSGVFLTFLSLSKLTHKTGFKETFIVVAVGSLIAEIIVITLGLLMY"
     gene            complement(40695..41471)
                     /locus_tag="OE968_000466"
     CDS             complement(40695..41471)
                     /locus_tag="OE968_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxybutyrate dehydrogenase"
                     /protein_id="HCP7217783.1"
                     /translation="MVKDKVVFVTGAASGIGKQIAESFLKNGAKVMFSDINQEALNNT
                     ITELQKKGYDCMSVKCDVTKEEEINHAIDKTVEKYGRLDILINNAGLQHVSMIEDFPT
                     DKFEFMIKIMLTAPFIATKKAFPIMKKQGFGRIINMASINGVIGFAGKAAYNSAKHGL
                     IGLTKVAALEAADSGITVNALCPGYVDTPLVRGQFNDLSKTRNIPLENVLEEVLYPLV
                     PQKRLLDVQEIADYAMFLASDNAKGITGQACLLDGGYTAQ"
     gene            complement(41576..42241)
                     /locus_tag="OE968_000467"
     CDS             complement(41576..42241)
                     /locus_tag="OE968_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacid CoA-transferase subunit B"
                     /protein_id="HCP7217784.1"
                     /translation="MDKLEMQEYIANRVSKELKDGAVVNLGIGLPTKVANYIPDNVNV
                     ILQSENGFLGLGSAEDGNSSDETIVNAGGQPVTILPGGCFFDSATSFGIIRGGHVDIT
                     VLGALQVDKYGNIANYMIPGKMVPGMGGAMDLVTGAKKVIVAMEHTSKGSAKILNNCT
                     LPLTATNAVDLIVTEMGVMEVTSDGILLKEINPAFTLDDVISATEAPLILSDSLNGKI
                     SVV"
     gene            complement(42241..42897)
                     /locus_tag="OE968_000468"
     CDS             complement(42241..42897)
                     /locus_tag="OE968_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase subunit A"
                     /protein_id="HCP7217785.1"
                     /translation="MNKIVSIDEALSHVKDGDTIMVGGFMANGSPENLIDYLCSKNIK
                     DLTLICNDTGFIDKGVGKMVVNKQFKKIIASHVGLNKETGRQMNNNETDVELVPQGTL
                     AEQIRAAGYGLGGILTPTGIGTLVEEGKQKIVVDSKEYLLEKPIYADVALLFASKVDK
                     AGNLVYKGSMNNFNNLMASAAKITIVEADEIVEIGDIDPNEVNTPGIFVNYIIEGGNL
                     "
     gene            complement(42906..44084)
                     /locus_tag="OE968_000469"
     CDS             complement(42906..44084)
                     /locus_tag="OE968_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000786547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HCP7217786.1"
                     /translation="MKDVVIVSAVRTPIGSFGGVFKNTSAVQLGTITVKEAISRVGLN
                     LSEIDEVIIGNVLQTGLGQNVARQIAINAGIPNSVPSYTVNKLCGSGLKSVQLAAQSI
                     TSGENDVVIAGGTENMSQAPYIVPTARFGSKMGDITMVDSMLTDGLIDAFNQYHMGIT
                     AENIATKFEFTREMQDKLALESQSKAENAIKNNRFKEEIVPVDVLIRRGKIETIDKDE
                     YPKLGMTFEGLAKLKPAFKKDGTVTAGNASGINDGAAMLILMSQQKADELGIRPLAKI
                     KSYASAGVEPEVMGTGPIPATRKALKKAGLSINDIDLIEANEAFAAQALAVKNELQID
                     SSKLNVNGGAIALGHPIGASGARILVTLIYEMQKRKVETGLATLCIGGGQGISMVVSR
                     "
     gene            44439..45341
                     /locus_tag="OE968_000470"
     CDS             44439..45341
                     /locus_tag="OE968_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCP7217787.1"
                     /translation="MDIKQLKYFVEIVKSGFNLSIASKTLHISQPALSQIIKNFEESE
                     DVYLFERYKGRLNGLTPAGERFYVNAEHIINEYKNMMEDLREDSVQFKGKVRIGIPPL
                     ILGIAFSDVVAQLVANNPDIEFDIVEKGAYDLNRMLILQELDYAVLLHPHKIDKSVVT
                     EHVLQEDELTAFLNINHPLAKKDKIDWNDLNEQLLAIFNPTFMIHHKLMQKFTDENVK
                     LKRYIMSGSWDFLLLSTTNSDFITILPSPVHDFFENSKIIEKPFNHPITWKVILCRPK
                     KERYSHVDQHVFKFIIDFFSKKNS"
     gene            complement(45557..46369)
                     /locus_tag="OE968_000471"
     CDS             complement(45557..46369)
                     /locus_tag="OE968_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCP7217788.1"
                     /translation="MFTSILKKLKKDKSFAFACITLSIIIILIIASFILNIDSNAIDT
                     TSKLQEPSLKHIFGTDELGRDYFSRALYGGRISLSVGILSMLISVVFGTAVGVISGYI
                     GGKLDQFLMRLIDMLMSIPSFLVLIVLNTYLTPKVSTIILIIGFLSWMEVSRIVRGET
                     LKIKENEYCLAAKATGIKTRNILLRHIVLNLKETIVVAGSLNIANAILTESALSFLGL
                     GIQLPLASWGNMLQDAQRHIFDKLYLAVFPGLLIFLTVMSLTIISKKFSSNT"
     gene            complement(46372..47331)
                     /locus_tag="OE968_000472"
     CDS             complement(46372..47331)
                     /locus_tag="OE968_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCP7217789.1"
                     /translation="MLKLILNRVKVLIPMLILISILSFGLLELAPGDPADAYINPLMS
                     SQDIENIRVNMGLDKPVYIRYLNWLKNTLSGNLGISYINHMPVTEQIMEKMGNTFILM
                     GTSLIFSILVAIPLGIFLAVNKNSITSKVSSVFNYIGVSIPSFWIGMILISIFSVKLN
                     IFPSGGMHTIGNDSIGDLVKHLVLPVITLGLYNTAIFTNYVEASVNEQLKKQYVITAR
                     AKGLSEKVILFKHVLKNSLTSLVTILGMSIQKLVTGAFVTEVVFSWPGMGRLMIDSIF
                     SRDYTVIMAITMLSALFLILGNLVADILYLLIDPKIKSSKGGF"
     gene            complement(47437..48996)
                     /locus_tag="OE968_000473"
     CDS             complement(47437..48996)
                     /locus_tag="OE968_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HCP7217790.1"
                     /translation="MKFKKLASLILVSSLMLTFTACASNDKDKSSGSKSGGTVVIPMA
                     SDPDIINGAFANVKEDSLASNIVYAPLYTYEKGNLVNYLAEKVDFKDSKELTIKLKSN
                     LKWHDGKPITAEDVLFTFNTVLDEKQNSPSRQYLLVGEKPVKVEKIDDLTVKITLPTA
                     SESFLYGISKISPIPKHVFEGESNIAKSEKNNNPVGSGAFKFKEWKKGESIVFEKNAD
                     YFGGEPKADSIALKIIPNEASQEAALNNGEISLMKTSAEGYEKAKSNSNLQTYTYSEE
                     RLNYIVFNQNISNMANKEVRQALSYALNRNEMIESAYGKEGSVPAKSILVPEADFYTE
                     EGVEGYDQDTNKAKDLLDKSGVKIDKLKIGYNTGRFGHKNYALVAQQELKKIGIEAEI
                     VPYESKAFFNILFSNSTECDMYVNGYAWGLEPNPYRGMFETGQYCNQTKYSNAEIDAL
                     WEKGFTELNKEKREEIYKQIQQDISKDAPIYTIDYEQNLMAAQKNLKGIKDAKPSPAI
                     LFEDWSKLYVE"
     gene            49215..50192
                     /locus_tag="OE968_000474"
     CDS             49215..50192
                     /locus_tag="OE968_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCP7217791.1"
                     /translation="MSKALIEVKDLKVYFHTDKGIVKSVNEVSFNINEGETIGIVGES
                     GCGKSVTAMSLMKLLPTSKIEGGEIIFRGKDILKMNEDELMGIRGNEISMIFQEPMTS
                     LNPAFTVGSQIIEGIMIHQDLSKEEAKKKVIDMIKLVEIPRAEEIYNSYPHELSGGMR
                     QRIMIAMALSCNPKLLIADEPTTALDVTIQAQILDIMKNIKEKLNTSIMMITHDLGVV
                     AEMCDKVLVMYAGKIIEVAEVVELFKNPKHPYTIGLLKSKPALGKNKDKRLYSIPGQV
                     PNPIGMPDSCYFSDRCEKVCDKCRTQIPPLIELNSGHSIACWLYKKEEI"
     gene            50193..51164
                     /locus_tag="OE968_000475"
     CDS             50193..51164
                     /locus_tag="OE968_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide ABC transporter ATP-binding protein"
                     /protein_id="HCP7217792.1"
                     /translation="MKKEESLLKVEGLKKYFEVKSGLFDKKIKSVKAVDGISFDLKKG
                     ETLAIVGESGCGKSTAGRTILRLIEKTEGKVEFNGVDIYKLEKEELRKLRPKMQMIFQ
                     DPYSSLNPRLNVEQIISEAVIEHNLVPKNEIKDNILNVVESCGLSKYHLNRKPGEFSG
                     GQRQRIGIARALALNPEFIVCDEPVSALDVSIQSQIINLLMDLQDKYKLSYLFISHDL
                     SVVNHIAHRVCVMYLGSIIEIATKGELYLHSQHPYTKALMSAVPIQDPTIKKNRIILK
                     GDIPSPTNPPSGCKFHTRCPYCKEICKKEIPVLKEISRNHFVACHLV"
     gene            51316..53358
                     /locus_tag="OE968_000476"
     CDS             51316..53358
                     /locus_tag="OE968_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HCP7217793.1"
                     /translation="MSILVTLLGLLVCTTISTVFSKKWSNIPLAIYQIVLGIILSILP
                     FKFSFSFNPEIFVICIIAPLLFSEGQNVSRKELLELRKPILLLAFGLVLITVFAGGIF
                     IHFLIPGMPLSVSFALAAVISPTDLVAVKSITQGLNFPKNIMSILEGESLLNDAAGVV
                     AFKVAVLATVTGVFSIEEAGIQFMITAFGGIIVGSILGYIIIKIRLSLHKWNLEEIPM
                     VIVIQIMTPLFVYFVAEEIGVSGILAVVMAGIAHGIEKEHLQNTTTKLRIISDNTWYV
                     LEYVLNGFVFTLLGFLLPSIYTGLSSKNENMALELTFISTLIVLILFVIRFIWVYLWH
                     NSFIKPKKNPLNNFFVGFLGFKDEEVIKESISKCKYSLIVATCGVHGTFTLATALSIP
                     FYLADKDVFPMRDTVLFISSEVILISLVLATILLPRLLKNNVQESEPLLSDKEAYKLI
                     LKEAILKLSNEKAQEVQPVIHDLNEQLVDSEKGILNTPDNKLISMMIAEADQQGLLAV
                     LKLLEDGKISDRAFKLYRFYITKSRKSVQKSIFKIVKLKISMWIINRKVKKEVKEKIT
                     KIVSENKEIIKEFHHAYALSTKTAISFINKNTDEDNRHEALIAIRFYNRYLNWITRKI
                     QNDDKFEARVEYYRVMAIQSQRDSVQQLVETKQISREVAKELLENILYDEMMMIES"
     gene            53619..54461
                     /locus_tag="OE968_000477"
     CDS             53619..54461
                     /locus_tag="OE968_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HCP7217794.1"
                     /translation="MIIQQIYNNNVVLVLDENIKKELILTGCGIGFQKKKGQEIDKSK
                     IERTFVIQDESFLDKISKLASQVDEKFFEVSTEIIAYAEENLNTKLYEYIYVALTDHI
                     AFAIKRYHENITIKNDLLHEIKRIHKKEYEIGKWAVDYINKEFDVKFPVDEAGFIAMH
                     IVNSNYKGSSKESLLITKIVKDILNIIRYYYRVEFKEDDINYDRLLTHLKFFAKRLVK
                     KEKINDTNNEIIDIIKVKYEKDYDCAYKIKTHVEKNYDYYVSQDELLYLTLHIKRVIS
                     VLNL"
     gene            54764..56836
                     /locus_tag="OE968_000478"
     CDS             54764..56836
                     /locus_tag="OE968_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HCP7217795.1"
                     /translation="MKKVFGVLQKVGKSLMLPVALLPAAGILLGVSNALAGDALLAHF
                     PALANPTFQLIISIMESSGQIIFNNLPLIFAVGVAVGLTEGEGVAALAAIVGFLILNT
                     SMGVMAGVTEDMVDNSMYANIVGIPTIQTGVFGGIIIGIVAAYLYKKFYKIELPQYLG
                     FFAGKRFVPIVTSLVAIAIGIILSFIWPPIQEGLLSFSKNVIEANQTLAAFMEGSLER
                     LLIPFGLHHVFHNPFWYQFGEYVNKAGELVMGDQKIFFAQLKDGVNFTAGTFMTGAFP
                     FMMFGLPAAALAMVHEAKPEKKKFVAGIMASAALTSFLTGITEPIEFAFLFVAPVLFA
                     IHCLFSGLSYAIMQLLGVKIGFTFSGGLIDFLLFGVLPNRTPWYLAILVGIGFAVLYY
                     SVFRFMIRKFNLKTPGREDESETNAEVIEMSKNELASEILIALGNKDNLKSLDACITR
                     LRLVVNDINKVDKEKLKSLGAAGVMVIGNNVQAIFGPKSDSIKSDIKDIIEGKTKVES
                     TVTKNVDKNKVKKNMEVANMENALVEKIDSLTNGEILDIEEVPDSVFSSKLMGDGFAI
                     KSSDGLIYSPVDGTIGVIFPTKHAIIIKSQKSGVEILIHLGIETVNLEGNGFEVFVNV
                     GDEVKAGEKLVKMDLEYIEKNGLSTISPVVFTNLEQNQKLSIKKGVSTAKEENRVSIL
                     RDDIEKIG"
     gene            complement(57049..57918)
                     /locus_tag="OE968_000479"
     CDS             complement(57049..57918)
                     /locus_tag="OE968_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCP7217796.1"
                     /translation="MDNKIGYLNDNFKIFNIRDKKDIQFEYHNHDFNKIIIFINGNVT
                     YFVDGIPYKLKPWDILFISNNEIHKPVIDSNVFYERIAIWISPEFMKKNSDASSDLEK
                     CFKIATENKCNRLRLNIHDIESIKSFIEQINISESNTEFGNEILRNALFIQLMIFLNR
                     IFLKNENMESTEDVFYDETIKKVLNYINSNIDDKLSIDSISSEFFISKYYLMRKFKSH
                     TGTSIHNYIVQKRLILAKSLITNGHLMSEVCNKCGFNDYSSFVRAFKKNYGVSPKNYI
                     NNKNPLDITLLDE"
     gene            58082..59536
                     /locus_tag="OE968_000480"
     CDS             58082..59536
                     /locus_tag="OE968_000480"
                     /EC_number="6.3.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HCP7217797.1"
                     /translation="MKLNDIIQGLDIINIKGELNIDINNVQYDSRKVTKGTLFICIKG
                     FVSDGHKYIKDAIEKGASAFLVEEDVEIKGCTFIKVKDTRKDMAKVADNFYNHPSQKF
                     NVIGVTGTNGKTSITTILNEILTLNKNKVGLIGTIKIFDGEKDIVSNSTTPESIDLQY
                     HFNNMLDNGCDYCAMEVSSHSLALNRVDETDFKLGIFTNLTPDHLDFHKDLEDYRKAK
                     EKLFFKTTMANIINIDDEGGKKIYENIKGINVPCYTYGVDTKADFMARDIKSDSDGVS
                     YRLITPSYEEVIFIPVPGMFTVYNTLAVIAACYVLGIPKPIYKEGLRLSNGVSGRFET
                     VPNDKGISVIVDYAHTPDALENVLKTTQQFAEGKIISVFGCGGDRDTEKRPLMGAIGQ
                     KYSDLCIITSDNPRTEEPEAIIKDILEGIDKKKENYHVVVDREQAIAEAISMAKKDDV
                     VIITGKGHETYQIIGKVKHHFDDKEVANECLSKM"
     gene            59807..62086
                     /locus_tag="OE968_000481"
     CDS             59807..62086
                     /locus_tag="OE968_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HCP7217798.1"
                     /translation="MLSDAKNNRYGLSIIAVISILVITISCLIYGSRLNKTLGEETNQ
                     YLSEIANQSVNVLKKQINGDIKLLESISIFIEGEESFEVDNILSILKRQAINSSFKRM
                     GVILPNGTAYTTDGYIEDFSKRDYFLKSMQGEVVITGKLKDVIEDDKNTNSNINVYSV
                     PIYKDNEVKGVIFATHSTKLYEKILSVPTFNGKGYSYITRSNGDIVLNPSSKNANSTK
                     ENLFSYIGRSDSISKSSINNMKSNIKNFKSGSLSYSMFGKGYYLSYAPIGINDWYLFS
                     EVPKTAISEKSYAIIKLTLSACVVLIIIFTALTIYILFIHKKSKEKLEEFAFKDNVTG
                     IGNSNKFNLEGGKFLSSHEKKNLVLIYFDIDKFKLVNDRFGYEEGDRVLKEIAEIIKN
                     IFKEQSVFSRISNDNFAIIFEKKNNRESIIEICELIRKKLSMIKTSLGVELNLIPSIG
                     VYFVEEGETNISTCLDKAMIAKTTVKRKYLKVYEIYAENLKETLIEERDIEQEMHDAL
                     KNEQFKVYLQPKVDLSTTKIVGAEALVRWQHPKKGLISPGVFIPIFEKNGFITELDMF
                     VFTQVCKNFKRWENENFPTFPISINLSRVHLENPGFISELERITKEYEIEPNLIEIEL
                     TESAIFDNTKILFKIMQTLKSVGFKISMDDFGSGYSSLNMLKDMPIDVLKLDRQFFIT
                     VGNAKKSQIVVSSIVQMAKQLDIKVVSEGVETVEQAEFLRFIGCDMAQGFLFARPMPI
                     EEYEKLILDRYSLNRKETN"
BASE COUNT        23279 a         7527 c        10297 g        21331 t
ORIGIN      
        1 aaataaaatc tataaacaaa atctatgaat taataggaaa ttatcaattt gttattagta
       61 aagtctcgtg atacaataaa tttataaaat ctagataaat agaaatcaaa aaatactttt
      121 atttttaagg taaaataata ctactagtag gataaataaa aatataaaat caaaaatact
      181 attaattata aagaaaataa agggggcaaa tttaagctat gaataatcaa aaaaatctta
      241 atattccaat tacaattagt tcttatacat tgggaacaga agtttcattc cgtgatagag
      301 ttcgtattgc aaaagaagct gggtttgatg gtattggatt gcgtgctgaa aattatattg
      361 atgcaaaaaa tgcaggtgtt acagatgaag aaatgattgc aattcttaat gaatatgata
      421 tgaaagttac agaagtagaa tatataactc aatggggaag agaagaagat agaacggaag
      481 ctcaaagaga aaaagagcaa aatgtttatc atatggctca cttatttaat gttaaacata
      541 taaattgtgg attattagag atgataccag aagaacaaat tataactgca ttgggagaat
      601 tatgtgacag agcaggtgaa cttattatag gtcttgagtt tatgccatat agtggtgtac
      661 cagatttggc tactgcatgg cgtgttgtga aaggatgtaa tcgtgaaaat gcaatgctta
      721 tattagatac ttggcactgg gctagagcaa agcagacagc agaggacctt gcacctgttc
      781 cagcagataa gatagtatca attcaagtgt gtgatgtttt agaaactcct tatgaaaaac
      841 ttagggatga atcactacat gaccgtttgg ctccaggtga aggatatgga aacacagagg
      901 aatttgtgaa aataataaaa gaacacaata tatcaccaag agtcataggg gcagaagtaa
      961 tatctgattc tctaatatct aaagggttat ccactgctgc tgaaactgta tttaatgcaa
     1021 ctaaaaaagt tttggataaa gcatggtctg aagtatctcc aaaataaact tatataatat
     1081 aaaaatatac agagtattat aatataaaac ttgaaaggaa ggaaaacctt atgaagatta
     1141 gttctatgtt tacacctata agaattggtt caatgacagt tccaaatcgt tttgtagttc
     1201 cccctatggg aaacaatttt gcaaacacag atggtacttt aagtgaaact tctaaggctt
     1261 attatcttga gcgtgcttta ggtggttttg gattaataac tatagaatct agtgttgtag
     1321 acaaaaaagc aaaaggaggt cctcgtaagc cttgtttata tgatgatagc acaatagata
     1381 gttttaaaaa tgtaatagat gcttgtcatg atgcaggttc gaaggtatct atacaattac
     1441 aacatgctgg ttctgaagga aatgaaaaag tagcaggaca tccattaaaa gctgcttctg
     1501 caatacctgc atcaaatggt cgtaatacac cactagcaat aacaacagaa gaaatatatg
     1561 aacttataga atcttatgga gatgctgcat tacgtgcaca aaaagctggt gcagatgctg
     1621 ttgaagttca ctgcgctcat ggatatctgg ttagtagttt tatatcacaa agaacaaata
     1681 agcgtgtaga tgagtttggt ggatgttttg aaaatagaat gagattacct cgtcttatca
     1741 ttgaaaatat acgtaaaaaa gtaggaaatt ctctagcaat attatgtcgt ataaacagca
     1801 ctgatgatgt tccaggagga attgatgtac acgatagttc agtaatagca gcatatctag
     1861 aagattgtgg aatagatgga cttcatgttt cacgtagtat acatatacat gatgaatata
     1921 tgtgggctcc tacgacttta catgctggat tcagtgcaga attagttact gaaataaaaa
     1981 aagctgttag tataccagta ataacagttg gacgttatac agagccacag tttgctgagt
     2041 taatggtcag acaaggaaga tgtgatttag tagcattcgg tagacaaagc ttggctgacc
     2101 cagaaatgcc taataaagct aaaaatggaa aactagacga aatgatacca tgtattgcat
     2161 gcttacaagg atgtgtacca aatatgttcc aaggcaaacc tatagcctgt cttgcaaatc
     2221 ctatattagg acatgaagca gagcttaagc cagctgaaat tagcaaagaa gttcttgttg
     2281 ttggtggagg tgttggaggt atgcttgcag catgggtatg tgctaaaaga ggacataatg
     2341 taactttagt tgaaaaatct gaagttcttg gtgggcaaat gcgtttagct gcatatcctc
     2401 cagggaaagg agatattact aacttagtta gaagttatat ttcaaaatgt aatcaatatg
     2461 gtgtaaaaat atgtactaat acagaagcta cagtagaact tataaaggag aaatcacctg
     2521 atgtagttat tatagctact ggagcaactc cacttgtact tcctatacca ggaatcaatg
     2581 attcaggatt aattcatgct gtagaccttc ttgatggtaa aaaatcttgt gggaaaaaag
     2641 tacttgttgt tggaggtgga atggttggat gtgaagtggc agccttcctt ggagaacaag
     2701 aacatgaggt tactgttatt gagcttagag aagaagttgg tgcagatgta atttcagaac
     2761 accgtaaatt ccttatgaat gattttgaaa attataatat acataccatt actggtgcaa
     2821 aagtttctaa attttatgat gatggtgtcg actatttact tacagatggc acagagcatg
     2881 atttaaaagg ttttgattca gtagtacttg ctatgggttc tcgtaattac gacccattaa
     2941 gtgaagttat aaaagaagtt gtaaaagaaa cttatattgt tggtgatgca gtaaaagctc
     3001 gtagggcatt agatgcaaca aaagaagctt ttgaagtagc attaaatata taaataataa
     3061 ataaattttt ctttgtaaat aactgaatag gttatttgca aagaaaatga taatattgag
     3121 aggagattat agttatggaa atttcaggta gaacaggatt atttgcatta ataggtacac
     3181 cggttggtca ctctaaatca ccagtgatgt ataattatag ttttaagaaa ttagatttag
     3241 attatagata tttagccttt gatatcacag tagataaggt aaaagaggca cttttagcaa
     3301 taaaaacttt taatataaaa ggagccaatg ttactatgcc atgtaaatct gctgttacag
     3361 aatatatgga tgaactttct ccagcagctc gtataattgg agcatgtaat acaattgtaa
     3421 atgacaatgg aaagttagtt ggtcatataa cagatggagt aggctatgtt cgtaatttaa
     3481 aagaaaatgg ggtagaagtt aaaggtaaaa agattacaat tatgggtgct ggtggtgcag
     3541 caactgctat acaagtacaa tgtgctttag atggagcaag agaaatatct atctttaatc
     3601 ctaaggatga tttttataaa agagcagagc aaacagttga gaatataaaa aaagatgtac
     3661 cagaatgtgt tgttaatcta tatgatttag aagatacaaa caaactttat gaggagatac
     3721 aatcaagtga tatattgaca aatgcaactc ttattggtat gaagccttat gacaatgaaa
     3781 caaatataaa agatactagt gttttaagaa aagatttagt agtaacagat gtcgtttata
     3841 atcctaagaa aacaaaaatg attgaagatg ctgaagctaa tggatgtaag gctattggtg
     3901 gattaggaat gttattatac caaggagcag aagcttttaa tctatatact ggattagaaa
     3961 tgcctgtaga agaagttaat gaattatgct ttaaatagat aagagtaata tcttaaacaa
     4021 tgaaaaaaca tacgtatttc aatattttta ataataaatt acaaattgtc atagtgggtt
     4081 ttgcctcata gtccagttaa atttgaagtt ttaactgact atactttaaa tccattatgg
     4141 ggatgagttt attgtacaca aaaatgttaa taaattaaca agaatgggag aaaaattatg
     4201 aacaataaaa aatattatcc tactgccata gcgttgtatt tttcatattt tttacttggt
     4261 attggaattt caattttagg acaatacaaa ccagaatttt catcaatgtg gggggctaaa
     4321 acattatcag atggaacatt ggatgtaagt attgttttag ctgttattgc tgcactagga
     4381 ttagggagac ttatatctta tccatttgca ggacctattt cagataagta tggaagaaaa
     4441 gtaagtggtc ttataggaaa ctttctacat gcaattttct ttgttggaat tgtattttca
     4501 ccaaattttt atatagcata tgtatttgca ataattggag gggcagcaaa ttcattctta
     4561 gatacctgtg taactccttc ttgtatggag atatttgcta gtttaggaac aatagcaaat
     4621 atgtttacta aatttacaat agctttagca caatttttgc ttccttttat aattggattt
     4681 gttgcagcaa attcaatatc atttaaagtt atttttatag taacagcgat tcttattgta
     4741 gtagatgcct ttttgatagc tgtgttacca tttccaccag ctaataatgt tattgataac
     4801 aaaggcaaaa cagttaaatc agagaagatg aaatttacac caacaagtat agctcttgtt
     4861 tgtattggat ttacatgtac atctacattt gtattatggt taaattgtaa tcaggaattg
     4921 ggtaaattgt atgggatggc tgaccctaca aaaattcaat ccttttactc aatgggagta
     4981 atatgtgcag tattaataac ttctttactt attaaaaaat atattaaacc aataagaata
     5041 ttagttatat atcctataat agctttactt atgctattag ttgtatattt tgttcaaact
     5101 ccaactattt gtatgttagg gggatttgta ataggttatt cagcagcagg aggtgttctt
     5161 cagttaacaa cgtcaactgc aaatgaaatg tttccaacta ataaaggaaa aataacatct
     5221 atagttatga ttgcatctag tatagcaaac tatgttattt taaatatagc aggtattatt
     5281 acaaaatcag ggggagttaa tggaccaaaa tatgttgtat tgtttaatgt ggcaataaca
     5341 tttgttggaa ttttacttgc attgtttgta aacatgagat atgaaaaaga aaaagtgtat
     5401 gattatgatg tctaatatta gtataatata tgcatagaga agtctaaatc taggatagat
     5461 ttttattaaa agtaattaaa attaataagg atattattta cagttataag atagggtatt
     5521 tacataatta ataataagga tattactaga atttcaattt ctagtaatat ttttttgcgt
     5581 ataaatgtaa acttgatgaa ataagtagta taatcaatat aaattacatc atgtaaagga
     5641 ggataatttg gtggagaatg tttttaagcg attgcaggaa tttaatggtt atgatggata
     5701 caaagaatca tttgaaatga attacctatg tatatatgaa agtataccgt taagagaaca
     5761 agtagagctt gcaaataatc tagtagatga aattttaaat atgtataaaa gtgaatctaa
     5821 tgaaatttat ttattggagg gtagtaattc taagtcttta atttgttatt tcgaaatttt
     5881 tatgaaaaag ataaatactt tggtaaaaga aatgattatt gatgagaaat ggttatataa
     5941 attaactaaa gaattaatat ataagagtaa aaaagttgag tatgtaaaac tagggttagt
     6001 tttaagtgag aaatatctaa atgtagaaaa cttaagagaa gttgtagata cattttctaa
     6061 atctggagaa tacgtatttt atctgagtaa tactattaaa aaacttgaat tttacaatac
     6121 atatttattt aatttatcta aaaaggctac aggttcaata aaagtatttg ctattgttaa
     6181 tatggaaaat ttagattcta aaataaattc ctatctaatt gaagatggtt ataaggatac
     6241 aaagtacgaa cgattattga tgaactatat tatttcaatt gtagatttga atgaatatct
     6301 tgaaaaacga gatttagata aagaaaagat aaataattta gcacgtctta tatgcaatta
     6361 cttgctaagt gtagaattta aatatatagg taataaatta gaattagtga atcgattttt
     6421 acctactgta gtaaattatg ggactaactt tgaaagttta tattcaattt tcctaatagc
     6481 tataaacgtc ttaaaagatg aaaatataga gtgcaataag attgaatttg aaaaagaaat
     6541 aaatggtatc ttgctcagtg aaaaatggaa aaatatatat tttgaagcat taagagatgc
     6601 tagtggaaaa acagaagata ttataaaaat gtcagaaatt tatgatgtaa acttatcttt
     6661 tgatgacttg ttgccatatc taaatagaga tattagagat tttgaggtat attggcatat
     6721 atctaaaaag ggaacgacaa gttctagatt aaaattatta aatttttttg aagagacgtt
     6781 taaaatagat gatttaattg gaaaaatgaa agatatagaa aaagataaat tgactcaaga
     6841 atattatgat gatatgttat tttttattgt gcttaaagga agtaaatcac tatatcctga
     6901 aggaaagaat atatctttaa aaggaatatt tggaaatata aatgaagtaa gaaaagaatc
     6961 cataaatatc ttaaaaagat acagagagaa actatctctt gaagaattaa aaattgttaa
     7021 agaagcgtat gaaaaagaaa aaaatgttat attgaaggat gaattaagaa gagtattata
     7081 tgaaagtaat aatttaaaaa aagaatttgt aaatattgaa aaaataaaag tagatgaaca
     7141 tggtaaggat atctatttga cttcaatagc tgttgctggt tcaaggttta gaaatagaga
     7201 atatcttgaa aaagaattgg agaaaagtaa gatatactat ttaactagag agaaagataa
     7261 tctatatgat gaaaaagcta ttaaaatagt tggtgaaact ggatatgtga taggctatgt
     7321 cccaagaaaa gaaaactata ttttgagcaa tttattagat ggaggaaaac tgctgtattg
     7381 tagagtaact gaatataatt tatatgaaga ttgtatctac gcaaatgtgt acttgagtta
     7441 taaagatgta attgaaacag ttgaaaactc tttaaagatg gttttagata agagtagaat
     7501 aaaacttata aactaagacg tttatatatt gcttagatga tgtaatccta actgattggt
     7561 tattttttct ggaattatgg tgtattttat gagcaatgct aatgaatata aaataaaaaa
     7621 acaattgttt tgtatatatg atgtatataa atatatttat atattcatat ttacaaaaca
     7681 attgaaattt atgttatttt ataattttaa atttagatgg aattttaact tctgctttat
     7741 cttttatttt agaagcttgt tttttaactt tatttaataa ttcagattca tctacaacta
     7801 atacttttct ttccttcatc aaccatttac catcacaaat agtagagtct acattttcac
     7861 tagtcataga ataaactata tttccaattg gattatgcat tggtaaacaa tgaattgtat
     7921 ctggatttag aataatcata tcagcttttt ttcctacttc aagactacca atttcttttt
     7981 ctagtaaagc acattttgct ccatttatag tagccatttc taagacttct tcagctggta
     8041 cgacagttgg gtttaaagtt cttcctttat gtattagtga tgtaagatac atgtccctca
     8101 taaggtccat tctattattt gaaggagctc catcagtacc aattgaaaca ggtattcctt
     8161 tttctaacat ttcaggaatt gatgcaaacc ctagaaccac tttcatagct gaacctgggt
     8221 catgagaaac ttttacatca tgtaatctaa ataaatcaat ttccttatga gtaagccaaa
     8281 ctgtatgagc agctaaaaga tttggtccta atacacctag tttatcaagg tattcaactg
     8341 ttccaactcc attgttttgc tttacaaatg aaatttcatc agctatttca gcaatatgca
     8401 tatgtatacc tgtattgtat ttatcagcta gttctttagt tctaacaagt aattcttcag
     8461 ttgtattaaa aatagttctt aatgcaaacc atattttaat tctctcatta gatgtattat
     8521 taaacttatg gaataagtct aattgagtgt tgatttcctc atcagtagtt ttttgccatg
     8581 cctcaggaag accatctcct gtatccataa ctgatttagc taaacaggct ctaagtccag
     8641 ttttatcaac agcttcaacc atagcatcta catattgacc accagattct aaaaatgtag
     8701 tgacaccaga ttttatcaat tcaacacaac atgcagtaga tgaaatcaag gaatcttcat
     8761 aattgaagct actttcgtat ggccaaattc tttctctaag ccaagttaaa agtacaacat
     8821 catctgcaag accacgtcct aattgttgag ataagtgaac atgagtattg actagccctg
     8881 gcattagtat ttttccttta gcatcatata tctctgcatc tttatctaca atattaatat
     8941 caaacttacc aacctctttt ataatattat tttcaataag tatgcttcca ttttcatata
     9001 cctctctatc tgcattcata gtaattagat atgcattttt tataagtaat tgtgacataa
     9061 acaccactcc ttttctatat atttttatat ctatatatta tgataataaa ttttctatac
     9121 aaagttaata gcaaaatcaa tttacatata aagtgatttt gctatttata aatttaaaat
     9181 aaataagatt ttattctata taatttaaaa tattgaccta gaactattta aaaatattaa
     9241 cttagaacta agtttacaac tgcaagtaaa cctataatcc aaagtgtaat actgatttta
     9301 tcagtttctt tagctactac atgcattatt atatatgaaa taaatccaaa gcataaacca
     9361 atacttatac tataagttaa aggcatcaat aaaactgtaa caaaagcagg tacagctatt
     9421 ttgctatcag caaaatcaat ctgttttatg ctttcaaaca tgaatacacc aaccattaca
     9481 agtgcaggag ctgcagcgta agtaggaact ataccaagta atggtgtaaa tataagtgta
     9541 gctaagaata atgctgctgt tactattgaa gcaagtcctg ttcttgcacc tgctgcaata
     9601 ccagaagcag attctccaaa tgttgtaaca gtactagttc ctaagaatga gcctattaaa
     9661 gtagaagaaa catctgcata taacattctt cctaaatctt ttatttcacc attctcatct
     9721 tcaagaccca tttgtttaca acaagtaata agaaatgcta atgaatcaaa catgtctata
     9781 aacatgaaag agaatatagg tccaattaat gagaatttca atgcacctac aatatctaat
     9841 ttaaaagcaa ctggtgctat actaggaggt gtcgagatta ttgctgttgg caactccaca
     9901 aatccaaata taacagatat tattgttgca actactatac ttatcaatat tccaccttta
     9961 acttttttat attctagtat tgccattaag ataagagcaa aaagagctat taaaactgtt
    10021 ggtgtaaaat ctgcaagtga aactatagta tctggattag ctattataac acccatattt
    10081 tttaaaccaa caaaagcaag gaaaagacct atacctgctg aagatgctac tgccaattct
    10141 ctaggaattg cgtctgcaat tgtctttcga agacctgtta ctgcgagtgt aaagaagaca
    10201 catccagata gaaaaactac cccaagacct gtttgccatg ggattcctgc acctataacc
    10261 aaagagtatg tgaagaatgc atttaatccc ataccaggag ctagagcaaa tggtgcattt
    10321 cctaaaatcg caaatataag tgtaccaatg gctgtagcta gtatggtaac tgttataagg
    10381 gcggctttat ccattccagc ttcagataat attgctggat ttacgaaaac tatgtatgcc
    10441 attgttaaaa atgtagtaac tccacctatt acctctgttt taaggctaga gccacgttcg
    10501 ctaaatttaa acattttgtc taaaaagctt aatgatgaat tatttccacc tggttgtaca
    10561 ttgttagtgt ttggtaccat ttttacctcc aaaaaacttt aagatataaa caaaaaaata
    10621 tatattcata tagatagaat agaacatata ttcagagttg acattctatt catagaaaac
    10681 ccatttaagg tgagtttgta gaaactatta gaccgtatta ctaatattat atgaacattt
    10741 tctatttgtt tttctgttgt attatatcgt aatattgtat tatttacaat aaatataata
    10801 aaattattcg tttttttgtc gattttataa aaaattaagg ttatttattg aaaaaaatta
    10861 ctttttccaa taattgaata tgtatgaata taatgtcaat tattctaact tgttttatac
    10921 tattaatgga agtttattat aaatgagttt gtgatataat tataaaagta ctgaatacat
    10981 ggatatttcg taaaaacttt ttaatatatc aaatatgtat attaagttaa tatattaaaa
    11041 aaaataatat caaaaataat ataatttata gtggagggga aaatgactaa aattattaaa
    11101 gtgcaaaaac ctaaatttac aggagaatta gaaattattg aaaatcttga agatatactt
    11161 gaagatatat ttaatgatga aaaaatattt aataaaatta tagaaaatga agttataagt
    11221 gatttagatt ctgtaagagt tagctttgaa tcttgtatat ttagaaatgt gtcttttgaa
    11281 aattgtaatt taaaaaagat tgatttactt gatgtggtat ttgaaaactg caatttatca
    11341 aatacatttt ttgatggagg aagtatatac agagttgaat ttaaaaatag taaattgata
    11401 ggagttagat ttgatgattg tatacttaaa aacgttttgt tcaaggatgt tttaggtaag
    11461 tattctaact tttcattctc taaatttaag atagtttcta tcttagattc aaattttgaa
    11521 aattctgtat ttcaagaagt aaaaggtgac aatctagtat ttgagtatac aaatttaaaa
    11581 aaagcaaact ttaatggaac taaactttct ggcatagatt ttactactaa taatattgag
    11641 ggaattgaga ttggtataga tgatattaga ggagcaattt ttgatgtgtc acaagcaatt
    11701 gatttaacga aattgatggg aattatcata aaatgaaaaa aatattcata aaataaattg
    11761 ggaaaacgtt aacaatgtgt gaatttttac cagattgaca tttttctgaa aataaagtaa
    11821 gattatctta atattcaaaa tattttcaaa gggggtaatt tagtgtgagt aagcagatga
    11881 gagatatttt tatagttggt tttgctttat tttctatgtt ctttggtgca ggaaatctta
    11941 tgtttcctcc atttttaggg atggaatccg gcaaagactg gttaattcct cttattggat
    12001 ttgttgttgc agatgctggt atagcaatgc ttgttattat agcaacagca agatgtaagg
    12061 gaagcatgga tgatgtactt aggagagctg gtaaagggtt agcaagagta atgagtgtag
    12121 ctgctctagc atgtttagca cttcttgtaa taccaagaac ttgcgcaaca acatatgaaa
    12181 tgggtattat gcctatattt ggagaccatg gtccagtagc taaagctgta ttttcaataa
    12241 tcttctttgg gctaacttta gcatttacta ttaggtcttc taaggttata gacataatag
    12301 gtaagtattt aactccagcg ttattattag tattatttgt tttaatagta aagggtataa
    12361 tttctccagc aggacctatg agtcctgagc atatgataga taaaaatcta tttggtgaag
    12421 gtatatcaca aggttatcaa acaatggacg ctctaggtgc agcatctatg gcaactataa
    12481 tgttgatgtc tataatagct aaaggatata catcagataa agaccaaata ggaatgacta
    12541 ttaaagctgg ttttgtagcc tgtgtatttc tagcagtagt atatggtggt cttacttatt
    12601 taggtgcaac agtttcaact ttatatgata ctagtatacc tcaagcatct ttattagttg
    12661 aaataactag tatattgtta tatggtcaag taggaaaggt aattttaggt gtaattgtgg
    12721 cacttgcctg tctgactact tctacaggtt taacagcatc aatatcaact tattttgaag
    12781 gaataagtaa ggcgagttat aaacaactgg ttataggtat atgtgtagct agtatgctta
    12841 tatcaaattt aggtgttgat tctataatag ccatatcagt tccaatccta caaactatat
    12901 atcctgtttt attagcaata gttgttatgg agttggctgg taaacatata aagaatgata
    12961 atgcttttaa aggtgcagca tatgttacat tagtgattag tttattatca gctataaatg
    13021 gaatgacagg agctgttcca tttatacaaa gcttgccact tgcaggtttg ggctttaact
    13081 gggtaatacc agctatattg ggtggaatag ttggtaactt tataaaaagc aacaaacaag
    13141 tagcataata atttgtaatt aatttaattt tataatatat taatttttag tactatgggt
    13201 aggtttaatc taaacctaat ctacccatag tactttttag attggattat aatagcatgt
    13261 atataatttt ttataatata atttttcttt gaagtatgat aaaattagta atagtgataa
    13321 gaatgtacaa atttaggagg ttttaattaa tgcttagaaa aataacagca tttatgctat
    13381 ccatatgttt aattattgga cttacaggtt gtagtttact tgtaggcaag aaagataaag
    13441 agaaaattat agatgatttt aaagttgcag tggtaactca accattatct gaaaataaag
    13501 tacaatacaa tatggtggaa gagatggcaa aagaatatga ggaagagaat aaaattgata
    13561 aagacaaaga tggtcaaact aaagttaaac aaactataaa gcatgttgta ttgccagaga
    13621 attttacttc taatatagac agtgctatta ataagatagt aaagttggct gacgataaag
    13681 aagttcaggc tattgtagtt tcaactgacc aagcagggct tttacctgct ttacaaaagg
    13741 taaaggaaaa gcgtccagaa ataataacta tttctgcccc tatgggagat gataaaaacc
    13801 aattaagcca atttgttgat gtgaatctag gggttagtgc agaggaaaga ggaaaagtat
    13861 tagctgaacg ttcaaaagaa atgggagcaa aagcttttat tcattatgcc tctacagatg
    13921 atttgaaaga tgttaatata gccaaaagat tagaaatgat taaagagact tgcaaaaata
    13981 taggattgcc atttgtacaa gttaatactc caaatataaa tactgaagaa gacaaaaaca
    14041 aagttaagca gtttttaaat gaagatattg aaaaacaagt taaaaaatat ggaaaagata
    14101 taaatgtatt tggtgtaaat gagtatatgg atgaagttat attgactaag gctttagaat
    14161 taaagtatat agttgcagag caaagcaatc catcaccaat acaaacatat cctagtgtta
    14221 tgggtctaaa aatatctgaa aaagatgctc aaaattatga taaaataaac gacatgataa
    14281 gtgaaaaggc taaggctttt ggcatgtcaa atagacttgg tggatatcct atgccaatgg
    14341 atgcttttct accatcagta gcaatttatc ttgctactga aatggtgaaa caagatttaa
    14401 cacaagaaga tgtatgtgac ccagattatt tagaggcgtt tacagaatta agatttggaa
    14461 tcggttcaga atttactcct ttaacagagg tactttataa ttatcaatca gtaattttaa
    14521 gccaattaat ttattaatat taaggaagtg tctcaaaatg aactttttag tttatgaggc
    14581 actctttttc tattaaatca aatatatttt tatcttttta acaattaaaa agaagcttat
    14641 ccctatattg agatagcttc gtttttaata taaataagtt ttattatttt ataaaaaatt
    14701 tatagaaaaa taaaaaatta taattatata taaattttga taaagtaaag atgaattact
    14761 ataggtttaa attatattat tttctattat ttttatgcct ttctcagtta ttgatgagcc
    14821 ttttcttcct ttactagaaa ttaagtatcc attgcgtgtc aaatattcta gcatatttct
    14881 tacttcgtat tctgtgacat tatattccat aaatttcatt aactttgtcc tccccattgg
    14941 tttcatgtgc aatgatttta ggatagaaat gcatatgttt ttgtcatatt ggtttaaatc
    15001 attgaatatg gacatattac ttgacatatg attattattt aattttgaag atatgttttg
    15061 aggtaaatca tttattgtaa gataattgga acccatgtaa gccatatatt caatacaatt
    15121 tctcagttct ctaatattcc ccatccaagt gtatgaattt aaagcttcta aaagactctt
    15181 atcgagtttt atgtttttat agggaagttc ttttaaaaat gattctaaaa gaagaggtat
    15241 atcttctaat ctctttctaa gaggaggtaa atctaaagtg aacatactta tcctataaaa
    15301 taaatccatc ctaaatttat tttctataat taatttctct aaatctttat ttgtggcagc
    15361 taatattctc acatcaattg gaataatact tgtaccacca atttttctaa tttctttttc
    15421 ttgtaagact cttaaaagtt taacctgtaa atcatgtggc atatctccta tctcatctaa
    15481 aaatatagtg ccagtgtgag ctaattcgaa taatcctttt tttccacctt tttttgctcc
    15541 agtaaaagaa ccatcttcat atccaaatag ttcactttca agtaattcac ttggtaatga
    15601 agcacaattt attgctacaa aaggtttatt ttttctattt gaatgattgt gtattgactg
    15661 agtaaaggct tctttacctg ttcctgtttc acctgttatt aatataggat tatctgtaag
    15721 agccattttt tttgcctttt taatacaatc ttttataata gaactatttc caataatatt
    15781 attaaattta tatttagcta cataacctct tttgacagaa tcacttctta ttttttgttc
    15841 taatatttct atattgttta catctttcaa tgtaattaag caaccctcta tatttttata
    15901 aagataaaat ggttttttag aaagtatgaa ttttttatct atttcgtcta tgtatataat
    15961 catattatcg atatttaagt tctttgtaat tttatctaag aaactatttg gcatatattc
    16021 cattaaggaa ggtgatttta taagtttttc atctagtccc aacatattaa gtaaagactt
    16081 atttacaaaa gtaaccttgt taaaggtgtt gaaaaatatt agaccatcac ctatttcatc
    16141 aatggtcatg taaagtatag tttttaattt agatatatta tctaatgatg tatttaagaa
    16201 atcatgactt agtgtctctt tggacaattt gtatagtttt tctataaatt tctcattttt
    16261 tagttttaat actactaata atgacatata tgtatctaat gagatttttc tccaacctaa
    16321 atcaacaata ttttttatgt attttggtat aaatctaatc tgacctggtg ttatagctgt
    16381 atctaaatca tatatttcat cacaatctgg atatgtcggt acaaaatcta tatgatttat
    16441 accaatttta tatagataag tagccatctc aaatgctgaa gttttattgg ttgtcataag
    16501 taacgatttt gtacctggag gtagtttcat cattttttca tatccaagtt ttgaaagtgc
    16561 tttcgttcca tgaataattt caatatcttc cttaaaatgt tttattaaaa aattactagt
    16621 taaaggtgat agagaaagca ctacatctcc ctctaaattt tcttttattc catcaagtat
    16681 attttgtgtt tctatgatta tttcgtctcc aaaaaagttt gttaattctt ctttgtagtg
    16741 gtcactattc aatttatcat gtgttataag gattaacttc tttttatcca ttttatttct
    16801 cctaacaaaa tagtatttat ttttaaagta tttaaagtat aaggcaagtt atattataca
    16861 acaaatagta gtataaattt atatatttga ttaaataata ggttttttta ggattttatc
    16921 ctataaaaac ctattttaaa attatttttg caagataagg aaaatagctt tttatattgt
    16981 aatgtatatt ttaaataatt aataaaaaaa tattatattt ttaaacttga aaagtaagta
    17041 attataagct atttaatcac tggaataaat ttacaataaa aaaataaata caaaggcttt
    17101 atcattaagg tattggcata agttttgctt attaaacaag tatactaata aaattcattt
    17161 aaacaggagg gagaatttat atgagtaaat tagaatcaac aacagaaaaa gttgaggtaa
    17221 aatggtatgg gtatgtagca ttaatattgg gagcattatt tttttcagga atatttaaag
    17281 atgcaccagg accattaaaa gtattggatt ttaacaatgt attaggttct tttggaacat
    17341 tgggaacaat taatgatggt gtaggtacat tagctgcaaa ctttagaggt gatggaggta
    17401 ctggccctcg agatggatgg ctatatgcat tgacattaat accatcagtt atgtttgcac
    17461 ttggagtagt tagagttata gaccacttag atggaatgaa ggcagctcaa aagcttctta
    17521 gtccactatt aaagccatta ttagggttac ctggatttgc aggactaact ttgatagcta
    17581 gtttacagtc tacagatgca gctgcatcta tgactaaaga acttaaagat gatgggtata
    17641 tagatgaaaa acaaaaagct gtattttgtg catttcaatt ttcaggtgcg tctgcaatta
    17701 cgaatttctt tgcttctgga gcagcactat ttccatttat aggagatgta ccaatattta
    17761 taccacttgc tttaatatta attatgaagt ttgttggggc gaacttactt agattatatt
    17821 taaataaatt tgacaagggg gaagcttaac atgagtgagg tagcaaaaaa agaagtaaaa
    17881 gttaaaaaag gaaatgtgat agatgcgttt attggaggag ctagaaatgg attccaaata
    17941 agtacaaatt caatggctcc aaatgtcatc ttcggttttg ctataatttc tgtgttcaat
    18001 ttaacaggtc ttttggatgt aatagggaca atatttacac ctgtaatgag tatctttgga
    18061 cttccaggtg ttgcagcaac agctataatg acaatattta tatcaatggg aggagcatct
    18121 ggagtaatcg caggtttatt tacagcaggt caaataagtc aagcacatgt tgcaattcta
    18181 ttgccaatgt tattgctttc aggagcgcag atacaattta tggggagact tttaggaaca
    18241 gctgagttaa aaactaaata ttatccacat atgtttgtta tagcaacttt aaatggttgt
    18301 attgcaatgc ttataatgaa ttatttcgta gtataggtaa ttataataaa gatttaatat
    18361 aaatggaaag tttaaatttt aaggaggagc tagattatgg aaactaacaa agactatatt
    18421 gagtatgtac ataaagtgta tgattatcta cacactatac cagaaaaagg atttgaagaa
    18481 tataagacat cagagtttgt tttaaaagag cttgaaaaaa tggggtttga aaatattaat
    18541 aaaggaattg caggaactgg tattatagta actatagatt ctaaaaaaga aggaccagta
    18601 tttgctataa gagcagatat ggatgcattg gaatttatca tagatggaga aaagaaaatg
    18661 atacatgctt gtggtcatga tggtcatact tctatgcttt taacagctgc aaagttaata
    18721 aaagagagaa atttagtaaa aagaggtaag ttaaaaatac tttttcaacc aggtgaagaa
    18781 aaattatatg gagcattaag agtaattgat tctggtttgt tggatgatgt agaagaaatg
    18841 gtagggatgc atttaagacc tggacaagat tgtaggttgg gaaaggcgat acctgcaatg
    18901 taccattgtg ctagctgtat aatggaattt acgattaaag gtatcacttg tcatggttct
    18961 aaaccacatt taggagtaaa tgcagtagat gctgtctgtt tagcagtgaa tgcaataaat
    19021 gcaataagag taaatccagc tataccaaat tctataaaag taacaaatat atcagttaag
    19081 ggagaaactt ataataatat accagatgaa gcatttatgg ctttagatat aagggcagaa
    19141 agtaatgata taatagaaga attaaaagaa aaagcaatac atgctgtaaa aactgctgta
    19201 agttctataa atgcagaagc tgtactaatt tccaaagatg gagtaccagc agcagaattt
    19261 gatgaagaac ttgtaaactt ggctgaagaa actataaaag atgtattggg agctgatgca
    19321 tctataggta tatttaaaaa ttctggtgga gaagatttcc attattatac acaaaaacta
    19381 aaatgtaaaa ctacatatat tggattagga gctgatgcta caccaggatt tcataatcca
    19441 aatgtaacat ttgatacgaa agctttagaa tatggtgtag atatatggtg tagattggtt
    19501 gaaaagagat tgggataaca tccaaactaa taattctaca tttaaaatta taattataga
    19561 agttatagaa aaagattgct tatgttaatt agaaaataat taatatgagc aatcttattt
    19621 tgatataatg aaactgattt tggaatattg aaaaaatatg atggaaaagt aattatattt
    19681 taaatctatt ggacaaaaaa gtgatattat tataatatta agaattgtaa aataatacca
    19741 aagtgcatct agtaatagac ttaacaatta taaaaatttt attcttagga gggaaaaaat
    19801 gagtaagtat aattttgaca gagtaataga tagagtagga acagattgtg taaaatggga
    19861 ttttagaact aattgttcaa caaaagcaca aaaagatggt ttgccttttt ggattgctga
    19921 tatggatttt gaatgtgcag aaccaataat agaagcatta cgtaaaaaag ttgaacataa
    19981 aatatttgga tatagttcaa atgatagtga taaatacttt aatgcagttt gtgattggta
    20041 taaaaggaga tttaactggg aaataaatag aaaagatatt atttttagtc ctggtgttgt
    20101 acctgctgtt gctattttag taagaatatt aactaattct aatgaaggtg taatagtcca
    20161 aaaaccagtg tattacccat ttgaagctaa gataaagagc aataataggg atgttgtaaa
    20221 caatcctctg atatatgaga atggtactta taggatggat tatgatgatt tagaagaaaa
    20281 agctaagtgt agcaacaata aagtactgat actttgtagt cctcacaacc ctgttggaag
    20341 agtttggaga gaagatgaat taaaaaaggt tgtagaaata tgtaaaaaat atgacctatg
    20401 gataatagct gatgagatac attctgattt aattagaaaa ggatttaaac atactccttt
    20461 acagtcatta tgcccagagt acaaggataa aatagttaca tgtatagctc caagtaaaac
    20521 atttaatctg gcaggaatgc agttgtctaa tataatagtg aataatgatg aactaaaaaa
    20581 gaaatatcaa gaagaggtta cagctgttgg agttgcaact tcaccaaatc cctttgctat
    20641 tgtagctaca atagcagcat ataatgaaag tgaagactgg cttaatgaat taaatgatta
    20701 cttagataat aatatacaat ttattgatga atacttaaaa gaaaacctac caaaagtaaa
    20761 acttgtttat ccagaaggaa catatctagc atggttagat tttactgctt atggattaaa
    20821 tgaagtagaa cttgaagatt taatgtttaa aaaagctaat gtattatttg atgaaggtta
    20881 tatatttgga aaagaaggaa taggatttga aagaataaat gtagcttgtc cacagtcttt
    20941 attaaaagaa tgtatggaca gattaaagac tatatttgaa aatttataaa gtataggtaa
    21001 aaatttataa agtgtttaaa aataaaaaaa taataaactt gacaaatttt aactaatcac
    21061 ttatcatact attatgaata aatagaaaac ataagagagc taaattttat tgaattaaac
    21121 tcttaaagac tttgaaagga agagtagtta tagaatgtaa ttaaagcgag ttggtgatgg
    21181 tgtgagacca atatgaagtc tataatgaag aacatcctgg agttgctaac cgaaatttta
    21241 aaagagtagg cttagtcgga accaaaccgt tatcatattg gggtgtatcg agtaatatct
    21301 gtacattgtg agctgggttt gaatttattt caaactaatc agggtggtac cgcggaaaag
    21361 caacctttcg tcccttttat atagggatga agggtttttt taatggaaaa atatataaat
    21421 atagggagtg aatgatatga gcacaataat accaaaggat tataaaagta gtttgaacgt
    21481 aattgataca caaatagcta taaaaaaatt aaaagatttt tttgaaatga gactaagtaa
    21541 tgaattaaat cttataagag tttcttctcc gttatttgta ttgccagaaa caggtgcaaa
    21601 tgataattta aatggagaaa aggctgtaag ctttgatata ccatttatga ataaaaatgc
    21661 agaaattgtt caatcacttg caaaatggaa aagattagcc cttaaaaaat atgggtttga
    21721 agttggtagt ggtttatata cagatatgaa tgcaataaga aaaaatgaag aattagacaa
    21781 tatacattct ctttatgtag accaatggga ttgggaattg gttatagata aaagtagtag
    21841 aaatgaaaag actctaaaag atgttgtaaa aagattgtat ggagtattta aagatactga
    21901 aatttttgta tgtagtatgt atgaaggtat aaaagaaata ttaccagaag aaataacttt
    21961 tataacatca caagagttag aagatatgta tccagaatta tcaccaaagg aaagagaaga
    22021 taaaattgta aaagagaaga aagcagtatt tataactcaa ataggaaaaa cattaatatc
    22081 aggagaaaaa catgatggaa gaagccctga ttatgatgat tgggaattga atggggatat
    22141 attattttac aatcctgttt tagattcagc attagaatta tcttcaatgg gaattagagt
    22201 tgatgaagaa tctcttgata gacaattgaa acttgctgga tgtgaagaga gaaaagagtt
    22261 tgactatcat aagatgcttt taaatggcga acttccgtat acaattggtg gaggaattgg
    22321 tcagtcaaga atatgtatgt atttcttaca aaaagctcat ataggagaag tacaagttgg
    22381 agtatggcca caggatatga ttcaaaattg tagtagtgca ggaattgaat tattataatt
    22441 taaatataaa ctaattgata aaatttatat ctaatatgtt catcaaatta attatatcgg
    22501 ttataatgta gaataaccta taattataag aggtgataaa tatggagttt ttaaaaataa
    22561 tcattaatat agttttagat attttaaaaa aaattttggt cagatttaaa aatgctaaat
    22621 ttggtttggt ttttgtattt gatttactta aactacctga ttttatgaca gataaaagaa
    22681 tcaatatagt tgataaaata aaggtaattt ctgtattaat ttttactata tcctactttg
    22741 tatctggggt tgatataatt ccagagatga ttgcaggggc atttggtttt atagatgatg
    22801 ctatagtttt aatttggagt ataggtatag tgaatgaaga aattaataag tatagagtta
    22861 tcgcaaaaaa agataaacat tcaaatataa ttgaaaatgt agaattttct ataaaagatg
    22921 aagaagaata acaatttata tatgttattc ttttttttat taacaaaaaa tggttaaatt
    22981 gttgacggag aggtaaaact ctattatcat aataagtgga tatccaatat ttaactaagt
    23041 attcaatgtg caagaatgct taatttaaaa aagttatgga gggtaaatat tatgaagaaa
    23101 aaaataggtt tagtgcccaa actaatcatc ggtatcatag tcggtatttt aatcggaagt
    23161 tatgcaccag aaataatagt acaaatatta gtaacagtta gtactttatt ctcagcattc
    23221 ctaaaatttg ttataccatt tataattata ggttttgtaa cagcaggtat agctgattta
    23281 gcaacaggtg caggaaagtt attggggata actacgggaa tagcatatgg ttctacctta
    23341 atagcaggat tattatcatt tgcagtatct acattaatct tcccaaattt tattgatgca
    23401 agtgttgcaa gtcaaattgg agacccagag gcaggaatgt tagctccaat attcacaatt
    23461 ccattagagc ctatggtaga tgtaacagct gcaatcgtat ttgcatttgt aatgggactt
    23521 ggaatatcag ctttaagaaa tcatggaaaa ggagagactt tatttaattt cttccaagaa
    23581 tttcaaggaa tcgtaacgaa aacgttgtca acagtgatta tacctttatt acctttatac
    23641 atagcaggaa cttttgcaaa tataactata gcaggggaag tatggacaat attaggggta
    23701 ttctggaaag tatacttagt agtaatacct ttacattttg tatatatggc atgtcaattc
    23761 acagcagcag gtgtattttc aggaaaaaat ccagtaagaa tgttaaaaaa tcaagtacct
    23821 ggatatttaa cagctatagg aactcaatct tcagcagcaa ctataccagt taatgttggt
    23881 tgtgcagaaa aaaatggagt aagtaagcaa ataagagaat ttgttgtacc tctttgtgca
    23941 acaatacatt tatcaggtag tatgatatca ataacaggat ttacaactgc agttttaatg
    24001 atgaatggta tgccacatgg aataggtgta ttattccctt atattgcaat gttaggtata
    24061 gcaatggttg cagcaccagg agcaccaggt ggggctataa tgagtgcact tcctttccta
    24121 ccaatggttg gaataccatc agatggtggg cttgcaagtt taatgatagc tttatactta
    24181 actcaagaca gttttggtac agcatgtaat gtatcaggag ataatgcaat agcagtagta
    24241 gtagataaaa taaatgatgg aatgagtaaa aaaggaaata aagaagagca aagtgcttag
    24301 ttttttaata atcaaaaatg agttatctca aatagagata gctcattttt tatggtataa
    24361 aaaattataa aataaagtga tttttttatt taaaaattgc tttaagagat gatattaata
    24421 atttattttc attaggtttt aatatacata ctctaaagaa atactcatct agaccttcaa
    24481 atgaacaaca atctcttatt attatttttt gtggaagcaa ttgttctcga agagatttag
    24541 cagtcaattc ctttgtcttg attttacaca atatgaaatt gcctttagta ttgtatatat
    24601 ctaagctttt tatattctta agctctttaa gcaggtaatc tctttcagtg ttcattaagg
    24661 aaatagtatt tgatataaaa tctaaatcac taaacatgat ttcacccatt ttagaagcta
    24721 ttatgtttat attccataaa tctagatttt tatttatttc atttttgaca ttagtgttag
    24781 atataagacc atatccaagc cttattccag gcgttgaaaa aaattttgat gtacctctta
    24841 taacgaataa attagaataa tcatcaacta attgagtaca agagtatgta tctgtatcag
    24901 taaactctac ataagtctca tcaatcatta aaaatgagtc tgtatttttt aaaatttctc
    24961 tcacttctac tttagtaaat gcaaatccag ttggattact aggattacag attactacca
    25021 aatcataatc tttagcattg atagttttta taagattttc taaatttata tgaaaattat
    25081 cttcttcttt tgcaaagtat ttttctatag aacaattaat tttagataac tctttttcat
    25141 actctgaata ggctggagag agtaaaagag cctgtttagg gttaattgta tgtataaatg
    25201 atgaaattag ttctgtagct ccactgccaa gtactatatt atctatagaa catttgcagt
    25261 aattggatat agaagttttt aagtctatgt aatcagggtc aggatacata gataccatat
    25321 ctatattgtt tacaatgtat tgtttggcta aacttgatgt accaaaagga tttatatttg
    25381 agctaaaatc cataaattct tcctttgaaa agccatactt actagataaa ctatataaat
    25441 tagctccatg gtttgtgctc ataaaagtac ctccaaaaat aaaattatat aatcgataaa
    25501 aataactgat taatatatgt acatatagat tataatacaa aggaatcgtt attccaaatt
    25561 tttaatggaa aaagcaaaaa agtatggata agctgttaat ttaggtttaa aaatgatgaa
    25621 aaagatttta attgatattt tggtatgcta taatatataa gttaatagaa ggaaagcggg
    25681 aggatacaaa atgtacaaag ttacaggaaa aatgttgaca gaagaacaaa taaaagaaaa
    25741 agtttatgaa ttaggaaaaa agatagaaga agactttaaa ggcgaagatt tactagtggt
    25801 aggtatactt aaaggagcta gtgtatttgt ttcagattta ataagatgta tagatttgga
    25861 tgtaaatata gattttatga gtgttacaag ttatggaaac tcaacagagt cttctggaac
    25921 agttaaaata ttaaaagatt tagatgtaga tattgaagga aagaatgtgt tgattgtaga
    25981 ggatataata gattctggtt taacattaag taatctagtt gcagctttaa aaactagaaa
    26041 tccaaaatct ttaaaactat gtactctact tgacaaacct cagagaagaa aagctaatat
    26101 acctgtagac tatgttggat ttgttataga agacaaattt attgttggtt atggaataga
    26161 ctatgctgaa aagtatagaa atttacctta tataggtata gttgaggatg tagaatagat
    26221 ttaaatgtga atcaaaagca ctaatttcta agggagttag tgctttttag ttaattatat
    26281 aaaattttag taaaggagac atctatatgg atattcagtt aaatatatta ttatttttcc
    26341 aaaatttaag aaatccaatt ttgaacttta tatttcttgt ctttacaata agcacagaag
    26401 caccgttatt aatattaatt acaacaatta tatactggtg tataaataaa aaatgtggac
    26461 agaaaatact gtttgctata attggaaatt ttgttgtaaa tttaggcatc aaagagtttg
    26521 taaaagctcc cagaccaata ggaataaaag gtcttgaatc attgagagtt tctactgctg
    26581 gtggttattc ttttccaagt gctcatactc aaactgcaac aacattttgg gttagtatta
    26641 tgactatatt taaaaagaga tatcttcatt taataggtgc agttatggtt ttaggagtag
    26701 gattgtctag gctgtattta gctgttcatt ggccaataga tgtgatagcg ggttggatat
    26761 taggaatatt ttttacagtt gtatttgtaa aaatatttga ctatattgat gataataaaa
    26821 attatatttt acttgtagtt ttacttatac catttataat agtggctata tttctaaata
    26881 gccctgaata ttttgaaaaa tttggtataa tagtaggatt tgtatttgga tatatggttg
    26941 aggatagatt tgttaaattt aatacagata ataataacaa aaaaataaat tttagtaata
    27001 aaaataaggg gagtaaaaat ataatttttt caagaatatg taggtttttg gttgggatag
    27061 taacaatagg aatgttatat attggcatta agttgtttat ttcaatgtta atagtcactt
    27121 taaatataag tgactctact atgagtataa tttttatgaa ttttattaag aatacagtag
    27181 ttgtttttta tggaatagca ggagctccag cattatttaa acttttaaaa ttaaattgat
    27241 tttaaggtat agagtcaata gtttaaatta aaaaaattaa gggtagaaaa gagtgattat
    27301 ttgaagaagg tagtaataat aggtggtgga ccagcaggga tgatagccgc atcaactgca
    27361 tgtgagaaag gctatgatgt aacattaatt gagaaaaatc ataaattagg aaaaaaactt
    27421 gcaataacag gaaaaggtag atgtaatatt actaacgctt gtgaaataga ggaattaata
    27481 gaaaatgtac ctacaaatgg aaaatttctt tatagtgctt tttatacttt tacaaatgat
    27541 gatgtaataa gtatgtttaa taatcttgga gtaaagacta aaacagaaag aggaaaaagg
    27601 gtttttccag agagtgataa agcatttgat attgtaaatg ctcttgaaag acaacttaaa
    27661 agtaagaaag taaatatatt attaaattcg aaagtagaaa aaataatatc taaaaataat
    27721 aaaattgaaa aagtaatttt aaacgataaa aaagaaatta agtgtgattc agttgtagta
    27781 gcaactggtg gattaagtta tccacttact ggttctactg gtgatggata taaatttgca
    27841 atttcacagg ggcacacaat tatagataca aaaccatctt taattggtat agaagtacaa
    27901 gaaagtttta caaaagattt agaaaaatta tcattgagaa atgttgaaat aagggtgttt
    27961 aatagcaaac aaaagaaagt ttatagtgat tttggagaac ttgaatttac taaatttggt
    28021 ttagatggac ctataatcaa gtctgcaagt tgtagaatga aagatacaag gaaagaaaat
    28081 tacactatat tattagattt aaaacctgca ttagatgagg aaaaattgga taaaagagtt
    28141 caaaaagatt ttcagaagta tacaaataaa aaatttgaaa aagcattaga tgatttactt
    28201 ccaaaaaaac taatacctat aataataaac ttaagtgaaa ttaatccaaa tacggttgtt
    28261 caccaaattt ctagagagca gagaaaaaac ttagtccatt tattaaaaaa tttaaagttt
    28321 acagtaaaga gatacagacc tattgaagaa gctataataa cttctggtgg tgtaaaagta
    28381 aacgaaataa attcaagtac aatggaatca aaattagtag aaggtttatt ttttgctgga
    28441 gaagtaatag atatagatgc atatacaggt ggattcaatt tgcaaatagc tttttctact
    28501 ggatatttgg caggttttaa ttgctaaaaa ttacctgaat taaaaatgtt taaaatcaca
    28561 taatattatc agcaacacaa aataaattaa acagaaggaa ggtaatcaac atggcaagta
    28621 acaataacaa caacagaaca gtagtaccag gagcaaaaga ggctttaaac caaatgaaat
    28681 tagaaatagc taatgaactt ggtatgagta attatcaaca agttgataaa ggaaacctta
    28741 ctgcaagaga aaatggttat gtaggtggat acatgactaa aaaattagtt gaaatggctg
    28801 aacaacaaat ggctggaaaa agcaacagat agttataaat aattatttat aactattggc
    28861 tattagttta gctagagcta tctcaaatat agaaagtaat ttctaaattg agatagcttt
    28921 tttttattaa attattaaat agatatattt ttatgtaata aattttatgt atttggataa
    28981 aataatacaa atgaatatgt tacataagga gtgatgtaaa atgagtagtg taaattttga
    29041 ggatttaaaa aacaaattta ttaatagtga cttagatgaa aaaataagaa tatatacaac
    29101 aacagaaggt ttatcagtag aacaatttaa agagctacta aaatattatc caatacaaca
    29161 tttatctaaa ctagaaaaag cacttggata gcagtattta atccaaaatt aaaaaggcaa
    29221 tttatttaat attaaaaata ttttttatta aataaattgc ctttttataa taggtttaaa
    29281 ttattatgct tttgatatat aattatagat tctctcattt ccaagttcaa tagacccagt
    29341 attaataaga gtaactattc cttctatatc tctagcagtt aagtatttat atggaattaa
    29401 taaattataa ccagtattac ttagtaagtt ttttaattgg gttatttgag agatattgaa
    29461 acattttgca gttttagtag atttttttct taagttagat aaattttcat tttgaatatt
    29521 tattaaagtt tctatatagt ttctataaga tatcttaaag tttgtctcat tgactatttt
    29581 ttcattaagt atactactga taaaatcttg agacaatata ttatctgcaa atttatctgc
    29641 tgttaatttt ccagatgtta tgcctttttg atattttcta agaatttttt tagtatagca
    29701 gtatatttta tttctcgttt ctaaatcgag ttgttctatt tgcacaaaac cacttccttc
    29761 taattataaa aatatttatt aaaaatctat acttaactaa taaagcttca ataacttatt
    29821 tacaataaat actaaatcat aaaatatttg ttatttttta ttattaccaa gtataaaaaa
    29881 tattataatt gtaaaactta caaatatatg taaaatattt aggagtgatg aaaatgttaa
    29941 atgggataat aaagcttttt tattctgaaa ttgtaaaaac aaagattaat aacttagatt
    30001 caagtggata ttctttaaga gatgaatgta aagaaatcag aaatataact ctaaagatag
    30061 atagtgtatt ttttaagctt ttaaagttag cttttggttc aatattgctt atggtagctt
    30121 ttaatttaaa catggtttta ggtataggag tgtttttagt tggtgtagtt tatatactat
    30181 ataaaagaaa tatggaagaa caagtaaaag agcatataaa taatgtgaaa aataatatcg
    30241 acatctctaa aataactttt atggatgaaa aagggagaac aggtctaaat gcattaatta
    30301 cattacttct tataggatta ttgacaggat ttaactggat attagttgct agttttgtcg
    30361 ttgtttttgt ttttactata aagaatgtat gttaaaatac taataaatag tttaatatat
    30421 agggggagaa attgagtatg actaatggca gttataaaat gaagaattta gtggaaatat
    30481 ccgctatggt gactgaatct acagattttt ttaatataaa agatgacata atagaaaaaa
    30541 tgttagaagt tgttcaccct acaaaggcat gtgtgaatct attttataaa aatgattcta
    30601 aatatgccta cttagtatgt tcgcaaacct tagaatatgt acctcaaatt tttccaataa
    30661 atagtcttaa aggtgcaaaa attgattttg acacatatcc agagtatata catgaggctg
    30721 taaatgaaaa aaaaataata tatgtggaaa atgtatttga agattctaga gcagaaggtg
    30781 aacgagattt agcaaaagct gaaggttata ttgggagaat agtttttcct tttataataa
    30841 ataacgtagt tgttggattt atgacttgtt ttttaaaaga ggatgattat ataacagaac
    30901 aagatataga ttttatatca tctgttgcat cactcttaag tttatcaata gaaataacta
    30961 ataaaaataa taatgtacaa attttaattg ataaactaag aggctcaata agtgccataa
    31021 atgaagctac taaaaaacta taccttaata agagtattga tggatttttg gaaaatttaa
    31081 gtaaacaagc gtgtaatatt actaatagta aagaagcttt aataattata aatagtcatc
    31141 ataataagga tgctatagtt agttgttata atgttgagca aaaaaagaaa acaaatttat
    31201 atcctatgat tgatatgttt ttaaagaaag agtcattggg ggggtattta aataatttaa
    31261 aaccatgctc aaaaaaggga ataaatttgg aaagttatat atattacaaa cttcaggata
    31321 aaaatgagac tataggatgt atagtttgtg caaatagcaa aaactatact agtgatgatt
    31381 taaatattct tagtatattg tccaaacaag tttctgttgg tatgcaatta tatgaacata
    31441 atgaaaagga agtaaaacac aaagttcttg aaaacgagtt gaacatatta aataaacaac
    31501 aacagcttat tatggataaa ggtaaaatgg attgtaatga tgagaaagaa ctttattttt
    31561 accataaacc agcaagggta gtaggtggag atttttatta tgctacaaaa gtggatgatg
    31621 aacatatagt ttatattgtt gctgatgtaa tgggacatgg aatggtatca aattatgttg
    31681 ttgcaatgat aaaaggtgct tttaaagtat tatgcaatca atacaataca ccaagagaaa
    31741 taatgacaaa tttaaatagg atgttatatg atgaatttga caagatggga gtatttacaa
    31801 cttgtttgat aggtattata gatactaaag aaaatatgat tactgtgtct aatgcaggtc
    31861 actatagtcc tgtagttgta aagaaagatg gcacaataga aaataattta aattgtaaaa
    31921 agggcatacc tattggaata atggaagatg ctacttatga aaataatact ctttcaatgg
    31981 aagattatgc aatggtatgt atgtacactg atggaatttt agagataaaa aattcatcaa
    32041 aagaagagta tggtataaac agattagaaa actttctaaa agaaaatttt agattaaatc
    32101 aacagttaat agtagaaaat ctaaaattgg atttaaagaa cttctcatca aaagataatt
    32161 atgatgatga tattttaata gttatgttaa aggataggta gattgattat ggattcaaac
    32221 gataaaaaag gacttaaaag tccagagatt ataataataa atggaagtcc aagaattaat
    32281 aaaaattgca gttttatagc aaatgaagta aaagctatgc tagaagagtg tggattaagt
    32341 tgtaaaatat ttaatatcta caatatggat attgaatatt gcacagcatg tggattttgt
    32401 gaaaaaacag ggtattgcaa gtttaatgat gatatgaagc cattatataa aatgtttgat
    32461 gattcaaaag gaactatagt aataagtcct gtacattttg attcaatatc agctaaatta
    32521 aagactgttg ttgatagaac tcaagctata tatgcaagta aatatgtatt aaataaacct
    32581 tcaattgata gaagtaagaa acggatagga atgtatattg cagtgggagg gagtaaatca
    32641 tatgattcac agtttaaagg tggacagatt gttatggatt ttttctttaa gagtataaat
    32701 actaaacttt tacacaatat atatttaaac aatacagatg atgtatctta tatagataat
    32761 caagaattta aagatataat atataaaaat ttaaagatat atattgattc aatataattt
    32821 gattttgtag gtaatattat gtataattgt attgcaataa tttaaataat taaaaggagg
    32881 gaatttcaat gaaattacca atagcattat ctaataaaca tgttcatttg agtcaagctg
    32941 atatagacgt attatttgga gcaggtcatg agttaactaa atttaaacca ttatctcaac
    33001 cagggcaata tgcctgtgaa gaaaaagtgg atttagtagg accaaaagga actttaaaag
    33061 gagttagagt actaggacca gctagagctc atactcaagt tgaaatatct ttagcagatg
    33121 gtttcccatt aggagtaaaa gcaccaataa aagaatctgg tgatatagct ggaactccag
    33181 gtgttaaatt agtaggacct gctggagaag ttgaaatgaa agaaggagtt atagttgctt
    33241 ctagacatat acatatgagc aatgaagatg ctgctaaatt tggtgtaact gataagcaaa
    33301 tagtaaaagt taaaacatct ggaccaagag cattagtatt tgaaaatgta ttagtaagag
    33361 ctagtgacag ctttaatcta gaaatgcatg ttgatatgga agagggaaat gcagcaggcg
    33421 ttaaaaatgg agatttagta gaattaatag ttgattaata ttataaatag actttatgct
    33481 agtagatatt ttatttgcta gcatattttt aaatgtaata aatttctata ggataaattt
    33541 aatcaattag attaatttat aaaataaagg ggtattataa aaaatgtaat aaaaacttac
    33601 aaaaatatga tgtaatatgg taaaattata tatataaaaa tttacatgta ataaggataa
    33661 gcattttact ttttatacta atatgaacaa atagataaaa aagtttgaaa aatctaactt
    33721 aatttattat atattgtata caaaattatg aaaaaaactt aacatattta attttaaaaa
    33781 aaatctactt aaatatgtaa ttaatttaca attttcaaag gaattttatc taatctgtag
    33841 tattatatta gaagatagag tatttgcgcg actatatgtg tgtttatagt tttgttgtgt
    33901 aaattatatg taaatataaa aaaatagact tgttataaac aagtacaatt gtagctatca
    33961 aggaggatac atattatggc taagtttatg aaaacacttg atggaaatac agctgcagct
    34021 catgttgcct atgcgtttac agatgtagca gctatatatc caatcacacc atcttcaact
    34081 atggctgaag tagttgatga gtgggcatca caaggaagaa aaaatatatt tggacaaaca
    34141 gttaatgttg ttgaaatgca gtcagaagca ggtgcatcag gaacattcca cggttcttta
    34201 caaggaggag ctttaacttc tacttttaca gcatctcaag gtttattatt aatgatacct
    34261 aacatgtata aagttgcagg agagttgtta ccaggagtat tccatgtaag tgctcgtgct
    34321 ttagcatctc aagctttatc aatatttggg gatcaccaag acgttatggc tgctagacaa
    34381 actggatgtg tattattagc ttctggttca gttcaagaag tagctgatat agcacctgtt
    34441 gcacatttag ctgcaataga aggtagatta ccatttatac atttctttga tggattcaga
    34501 acttcacatg aaatccaaaa agttgaatta ctagaaaatg aagattatgc aagtttatta
    34561 aactttgaag cagttcaagc atttagagat aatgctttat ctccaaatca tccagttgct
    34621 cgtggtactg ctcaaaaccc agatatatat ttccaaacta gagaagcttc taataaatac
    34681 tatcaaaata tagtaggtat agttgaaaaa tacatggaaa aaatgagtaa tttaacaggt
    34741 agaaaacata gtttatttga ttactatgga gcagaagatg ctaaatacgt attaatagct
    34801 atgggttcag taacagaaac aatagaagaa actatagatt acttaaatgc taagggagaa
    34861 aaatatggtt tagttaaagt tcatttatat agaccattct caatgaaaca tttcttagat
    34921 gctatgccat ctactgttga aagaatatgt gtacttgata gaactaaaga gccaggttca
    34981 actggtgaac cattatactt agatgtacgt gatgtattct atggaaaaga aaatgctcct
    35041 atgataatag gtggaagata cggattaggt tcaaaagata ctactccttc agatataaaa
    35101 actgtttttg ataacttagt ttcagaacaa cctaaaaatg gatttacagt aggtatagtt
    35161 gatgatgtaa ctaatacttc tttaactcca tctgagccaa taaaaatagc ttctaaagga
    35221 actataagat gtaagttctg gggattaggt tctgacggta ctgttggagc taataaacaa
    35281 gctatcaaaa taatcggtga ccatactgaa aaatatgctc aagcttactt tgattatgac
    35341 tctaaaaaat ctggtggtat aactatgtct cacttaagat ttggtgatac tccaataaga
    35401 gctacttatt taatagatga agctgattat attgcctgtc ataaacaatc atatgtttat
    35461 caatatgatt tattaaaagg tcttaaaaaa ggtggtacat ttgtacttaa cactatatgg
    35521 gaccaagcag gacttgaaga acatttacca gctcatatga aacaatatat agctaaaaat
    35581 gatataaaat tctatacagt taacgctgtt aaactaggac aagaaatagg tcttggaaac
    35641 agaataaaca tgataatgca atctgcattc tttaaattag ctgaaataat accagaagaa
    35701 gatgctgtta aatacttaaa agattctata gttaaagctt atggtaaaaa aggtgaaaaa
    35761 atagttaaca tgaactatgc tgctgttgat gcaggaataa atgctttagt taaagttgaa
    35821 gttccagctt cttgggaaaa tgctgttgat gcagataaag gagaagttaa agaaccagaa
    35881 tttataaaaa atatactaag accaatgact gcacaagaag gaaacaactt accagtaagt
    35941 acattcaatg gtatagaaga tggaacattc ccttgtggta ctgcagctta tgaaaaacgt
    36001 ggtatagctg ttgatgttcc tgaatggata atagataact gtattcaatg taaccaatgt
    36061 tcttttatat gtcctcattc atgtataaga ccagtattag ttactgaaga agaattagct
    36121 aatgctccag aaggatttga agctaaaaaa gcattaggta aaggattaga aggattaaaa
    36181 tatagaatgc aacttagtcc acttgactgt acaggatgtg gaaactgtgc tgacatatgt
    36241 ccagctaaag aaaaagcttt agttatgaag ccaatagata ctcaacttga tacagagtta
    36301 gataattggg catttgcagt aaatcctgat gaggtagctc caaaaggtga tgttatgcct
    36361 gcaaacactg ttaaaggaag tcaatttaga caaccattaa tggagttttc aggagcatgt
    36421 gctggatgtg gagaaactgc atacattaaa gtagttacac aattatatgg agatagaatg
    36481 atgatagcta atgctactgg atgttcttct atatggggag cttctgcacc atcaattcct
    36541 tatacttgta accatgaagg taaaggtcca tcttgggcaa actctttatt cgaggataat
    36601 gctgaatatg gatttggtat gtacacagct gttaagcaaa taagaaataa aatagtagat
    36661 gctatgacag agttagtttc tatggatatc tgtgaagatg ctaaagcggt atttacagag
    36721 tggttagatt ctagaaatga tggagaagct tctaaagtag caagtgctaa ggttgttgaa
    36781 ttattagaaa aaccagcttg tgattgtaca gatgaaaaag ctaaagagtt agtaaaagct
    36841 ataaaagata gaaaagatta tctagttaag agatctcaat ggatactagg tggagacggt
    36901 tgggcatatg atatcggtta cggtggatta gaccatgttc ttgcatctgg tgaagatgta
    36961 aacgtacttg tatttgatac agaagtatat tcaaatacag gaggtcaagc ttctaaagct
    37021 actccagctg ctgctatggc taagtttgct gcttcaggta aaaaatctag aaagaaagat
    37081 ttaggaatga tggctatgac atatggaaac gtatatgtag ctcaagttgc tatgggtgct
    37141 gataaaaacc aatttatcaa agccgttata gaagctgaaa aacatgatgg gccatcttta
    37201 ataatagctt atgctccatg tataaaccat ggattaaaag aaggtatggg aagaactgta
    37261 gctaacgaag cacaagctgt tgcttgcgga tactggcatt tatacagatt caatccagaa
    37321 gtaaaagctg aaggtaaaaa cccattcact ttagattcaa aagaaccaac tgcaagcttc
    37381 aaagatttca tacttgcaca agtaagatat tctgctatag ctaaacaatt cccagaggaa
    37441 gctgatggat tatttgctaa agctgaagct gatgctaaag aaagatatga aggatacaaa
    37501 aaattagctg aataatatta aagtattata atgcttatat agaattgata aaagagagtg
    37561 tctcaaagtg agctttttag ttcatgaggc actctttttg tatgaaatca aatatatttt
    37621 aatcatttca acaatgaaaa aggccttatc tctattttga gacagccttt ttttatgaag
    37681 atattaagat cctgttttta cctattaaat atctttttaa gttttccatt ttcatcttgc
    37741 caatactttt tatatattgc tctacacact aaaattaaga gaacaaataa tatttatagt
    37801 atgtatattt ggatttgata attttaaaat agatacaaaa gagtatctca tttgtgtttt
    37861 ttatcactta gagataatct tttgatatgt atggaaaaag attattttat cctacaaaga
    37921 tttgtgtcca ataaattgaa ccaccacttt tttgtgctac tccaacacct attttactga
    37981 aatttggatt cattatattt tttctgtgac cttcagaatt catccatgca tttacaactt
    38041 ctttaggagt tttttgaccc atagctatat tttcacctgc tgtcttatag cttattccaa
    38101 attttttcaa catgtcaaat ggagaaccat aagttggaga attgtgtgaa aaatagttgt
    38161 tatcaatcat atcttgagat ttttttgtag caacatttga tatagaagaa tcaagagtaa
    38221 gaggatttaa tccagcttta gctctttcta tatttactaa gtcaacaact tctttttggt
    38281 aagctgaaaa actttcactt gtagagcctg agttgttatt atcatcaggt ttgttagtag
    38341 agtctgaatt attgttgtct tcaggtttat cagtagagcc tgaattattg ttgtcttcag
    38401 gtttattaga ctcaggttta ttattatcag gtttattagt agagcctgaa ttattgttgt
    38461 cttcaggttt attagactca ggtttattgt taccaggctt attagtagag tctgaattat
    38521 tgttgtcctc aggtttatta gtgttgttgc aattcttgtc attatgattc ttatccttac
    38581 aagagttatc tttatcaggc ttaagttctg gttttacaga acaatttggt tttgcagaaa
    38641 acttgtattt agtattacta tatactaaac ttttgttact tatatttaca ttattttcaa
    38701 gtgatgaagc acttgcagta acagcacttg aagctgttgc taaagttaac actcctaaag
    38761 ctaatatagt ttttaatttt gttggtatat ttcttctcat cattaaacac ctcttaatct
    38821 aaaaattcta aaaatgttac tgatttgtaa cctttagtgt agggggttac ccgtgaatct
    38881 atactaacat aagattaaga ctttttttac tgtaaagata tgtaaaaaag atatatatgg
    38941 aataaatagg tatatttcag tgtgtttgac aatttgtatt aaaagcctgt atagtatgga
    39001 attacttagt tagagaaaat aatattttta taataattcc ataacgtaaa tttatagtta
    39061 tgataaattt ttttttattt ggttaaattt attcagtaga tgctttcgta ttagcaacaa
    39121 attataatta tttaaatctt taagaaataa aaagggtctg tctcaaaata gagataaggc
    39181 cttttttatt gtttaaatga taggcatatg ttatttcata taaaaagagt gtctcattaa
    39241 gtaaaaagtt cactttgaga caccaccttt catattatga attttaattt gttttatatt
    39301 aatacattag taatcctaat gtaattacaa taatttctgc tattagtgaa ccaactgcaa
    39361 ctacaatgaa agtttcttta aatccagttt tatgtgttaa cttagataag cttaagaatg
    39421 taagaaaaac accactttgt ggaactatag ttagtatatt tgaagctatt gtagcaacac
    39481 ggtgaattaa ttctggattt agaccagtac ttaaataata atctgcaaag tttggcatta
    39541 ctattcctaa tgcaccagaa gaggaccctg ttattgctga cattgttgaa gtcaaaacag
    39601 taagacttat aagtggacta cctggtattg acattataag tttgctaaat acatcaaaac
    39661 caggtgcagc cattattact gctccaaatg caactgcaga agatgtagca aatataggac
    39721 ctatagaacc actagcacct atgctcaatg tctgtatctt agatgataga aatttatgga
    39781 ataaaaaagc agataaaaga attgcaacta ttaaagctat gtaaattaca ttttttttca
    39841 taaattctga accaaaagta cttccagtta tagctataat tacgagtgct aatagaggaa
    39901 aaatacttgc aaaaaatcct ggtaattctc tatctaaaga ttcttcttct aattctgaag
    39961 tataagttgc ataagtttca ccttttctaa tacttttgtt tagagcatat ttcatataga
    40021 caagtccaaa cgtagcacaa cctatactac ctacaatact tggtatagta gctgcagtaa
    40081 gagacgtatt tagatattga ataggtataa cattttgaat ggctggtgtt ccaggaatta
    40141 tagtcatagt aattgttgca ataccaagcc aaagtggtat ctgaataagg ttccaagaaa
    40201 tatcaagttt tttaaataga gttcttgcaa gtggaatgac cgcaaacata actacaaata
    40261 agcttatacc accatacgtt aatataaaac ttactataaa tatagcaact aaaactctat
    40321 aaggatgatt agagccaaat ttatttaaaa taaaatcagc tattgataca gtagctccac
    40381 tttcttccat aaatttagca agtattgagc ctaataagaa tattgcaaaa taactcatta
    40441 tatagtttcc aagtgcaccc atataattgt ttttgtcagc acctagcatt gatgttacaa
    40501 catccatttt atttaaaata acaactatta aagttgctat tggagcagct atagttatat
    40561 gaatttcttt aactgaaaaa tatataatag ctatgatacc aataattata ccaattggtg
    40621 cgataatact cataaatatc cctccttagt agaaggacct gaagaatact ttcttcaagc
    40681 cctaaatata ataactattg tgcagtatat cctccatcta gtaagcaagc ttgtcctgta
    40741 atacccttag cattatcact tgctaagaac atagcatagt cggcaatttc ttgaacatct
    40801 aataggcgtt tttgtggtac aagtgggtat aaaacttcct ctaagacatt ttccaatggt
    40861 atattacgag tttttgaaag gtcattgaac tgacctctga caagtggagt atctacatat
    40921 ccagggcata aagcattaac tgttatacca gaatcggcag cttcaagagc agcaactttt
    40981 gttagtccaa taagtccatg ttttgctgag ttataagcag cctttccagc aaatcctatt
    41041 acaccattga ttgaggccat atttattata cgaccaaagc cttgtttttt cattatagga
    41101 aatgcttttt tagtagctat aaaaggtgct gtcagcatta tttttatcat aaattcaaat
    41161 ttatcagttg ggaaatcttc tatcatagaa acatgttgaa gtccagcatt gtttattaat
    41221 atatctaatc tgccatactt ttcaacagtt ttgtctatag cgtggttaat ttcttcttcc
    41281 ttagttacat cacactttac actcatgcaa tcataacctt ttttttgtaa ctctgttatg
    41341 gtattattta aagcttcttg atttatatca gagaacatta ctttagcacc attttttaag
    41401 aacgattcag ctatttgttt acctattcca cttgcagctc ctgttacgaa tacaacttta
    41461 tctttaacca ttttcatttc ctccaatttt attttatttt tatattaata ttttaagcaa
    41521 tacaaattta tatgtaatac gtctaagaga tttttatttt ctagttttaa ttattttaaa
    41581 caacagatat ttttccattt aatgaatctg acaatattaa aggagcctca gtagcagaaa
    41641 taacatcatc taatgtgaaa gctggattta tttctttaag taaaattcca tctgatgtta
    41701 cttccataac tcccatttca gtaactatca aatctacagc atttgttgca gtaagtggaa
    41761 gagtacaatt atttaatatt tttgcagaac cttttgaagt atgttccatt gctacaataa
    41821 cttttttagc tccagttact aggtccatag ctccacccat acctggaacc atcttacctg
    41881 gaatcatata gtttgctata ttaccatatt tgtcaacctg aagtgcgcca agaacagtta
    41941 tatcaacatg acctcctctg attattccaa aagaagtagc actatcaaag aaacatcctc
    42001 caggaagtat agtaactggt tgaccacctg catttacaat agtttcatca cttgaatttc
    42061 catcttcggc tgaacctaaa cctaaaaagc cattttcaga ttgtaagata acgtttacat
    42121 tatccggaat ataatttgct actttggttg gtagacctat tccaaggttt acaacggctc
    42181 cgtcttttaa ttctttagat actctatttg caatatattc ttgcatttct aatttatcca
    42241 ttataaatta cctccttcaa tgatgtaatt cacaaaaata cctggtgtat taacttcatt
    42301 tgggtcaata tcaccaattt caacgatttc atctgcttca actattgtaa ttttggcagc
    42361 agatgccatt aaattattaa aattgttcat agagccttta taaactagat tacctgcttt
    42421 atcgaccttt gatgcaaata gaagagcaac atctgcataa attggttttt caagaaggta
    42481 ttctttgcta tcgacaacaa ttttttgctt tccctcctca acaagagtac caataccagt
    42541 cggtgtgagt atacctccta gaccataacc agctgcacgt atttgttcag caagagttcc
    42601 ctgaggaact aactcaacat ctgtttcatt gttattcatt tgtcttccag tttctttatt
    42661 taatcctaca tgagaagcaa ttatcttttt aaattgctta tttacaacca ttttgccaac
    42721 tcctttgtca ataaagccag tatcattgca aattagtgtc aaatctttta tatttttact
    42781 acataaataa tcaattaaat tttctggtga accattggcc atgaatccac caaccattat
    42841 tgtatctcca tcttttacat gagatagagc ttcatcaatg ctaactattt tattcatatt
    42901 tcctcctatc gtgaaaccac cattgatatt ccttgaccac caccaataca aagtgttgca
    42961 agtccagttt caactttacg tttttgcatt tcataaatta aggtaacaag tattctagct
    43021 ccacttgctc ctattggatg tcctaatgct attgcaccac cattaacatt taactttgat
    43081 gaatctattt gaagttcatt tttaacagct aatgcttggg cagcaaacgc ttcatttgct
    43141 tctattaagt ctatatcatt gatgctaagt ccagcttttt tcagtgcttt tctagttgca
    43201 gggattggac cagtacccat gacttcaggt tcaacaccag ctgaagcata ggattttatt
    43261 ttagcaagtg gtctaatacc tagttcgtct gctttttgtt ggctcattag tattaacata
    43321 gccgcaccat cattaatacc tgaggcattt ccagctgtta cagtaccatc ttttttgaat
    43381 gcaggtttaa gtttagctaa accttcaaat gtcataccta atttaggata ttcatcttta
    43441 tcaatagttt ctatttttcc tcgacgtatt aaaacatcta ctggaacgat ttcttcttta
    43501 aagcggttgt tttttatagc attctcagcc ttactttgac tttctaatgc caatttatct
    43561 tgcatttctc tagtaaattc aaatttagtt gcaatatttt ctgcagttat tcccatatga
    43621 tactgattga aagcatcaat aaggccatct gttagcatac tatctaccat ggttatgtca
    43681 cccattttac taccaaagcg agcagttgga acgatataag gagcttggct catattttca
    43741 gtaccacctg caattaccac atcattttca ccagatgtga ttgattgggc agctagctgg
    43801 acacttttaa gccctgaacc acataattta tttactgtgt agcttggaac agaatttggt
    43861 atacctgcat ttatagcaat ttgtctagca acattctgtc caagccctgt ttgaagaaca
    43921 tttccaatta ttacttcatc tatttcagat aaattaagtc ctacacgtga tatcgcttct
    43981 ttaacagtga tagttccaag ttgaacagct gaagtatttt taaatacacc tccaaaactt
    44041 cctataggtg ttctgactgc tgatacgatt actacatctt tcatatctaa tagttacctt
    44101 tcttgaatga taattaaaaa ttttctgaat aaagaaatta ggaaacacta taataaagta
    44161 cttttttaat acaagcttgt ttttaagtat ttcaattact tttattccta atgctttagg
    44221 ttttcctgtt tctaattata gattacggcg aaaaaagcgt tttgtctaag tctaattttt
    44281 tatatagtgt ataagaaaaa tttataggat aaaaatttat agtagattta gaaaaatatt
    44341 ttgttaaaat attaatgaaa ttatgttgat tttcctataa aatatcatta gaagaaaaaa
    44401 tataatctaa attatacttt tggggaaggg ggtttaaaat ggatataaaa cagttgaaat
    44461 attttgttga aatagtgaaa tctggtttta atttatcaat agcatctaag acacttcaca
    44521 tatctcaacc agcattaagt caaattataa aaaattttga agaaagtgaa gatgtatatt
    44581 tatttgaaag gtataaaggc aggttaaatg ggttaacacc agcaggagaa agattttatg
    44641 taaatgcaga acatatcata aatgaataca aaaatatgat ggaagattta agagaagatt
    44701 cagttcaatt taaaggaaaa gttagaatag gaatacctcc acttatactt ggaatagcat
    44761 tttcagatgt agttgcacag ttagttgcaa ataatccaga tatagaattt gatatagtag
    44821 agaagggtgc atatgactta aatagaatgc ttatcttaca ggaattagat tatgcagtat
    44881 tgttacatcc acataaaatt gataaaagtg tagtaactga acatgtgctt caagaagatg
    44941 aacttacagc atttttaaat ataaatcatc cacttgctaa gaaggataag atagattgga
    45001 acgatttgaa tgagcagtta cttgcaatat ttaatcctac ttttatgata catcataagc
    45061 taatgcaaaa atttactgat gaaaatgtta agttaaaaag atatataatg tctggttcat
    45121 gggatttttt gttgctatca accacaaatt ctgattttat aacaattcta ccatcaccag
    45181 ttcatgattt ttttgaaaat agcaaaatta tagaaaagcc ttttaatcat cctattacat
    45241 ggaaagttat attatgtaga cctaaaaaag aacgttatag ccatgtagac caacatgtat
    45301 ttaaatttat tatagatttc tttagtaaaa agaactctta aaaatgttat taaaataaca
    45361 aataaataaa tcaattttta ttataataaa ctattagttt ttcatctata tgtttgagag
    45421 caataatagg ttttacataa catggtagag tagtatttaa agttataata tacaaaatat
    45481 gtattttttt aaacgaaaaa taaaaacagt gtatatcttt agataatcac tgtttttatt
    45541 ttctatataa aatttgttaa gtattactag aaaatttttt gcttattata gtcaaactca
    45601 tgactgttaa aaatataagt aatcctggaa atacagctaa atataacttg tcaaaaatat
    45661 gtctttgagc atcttgaagc atattacccc atgatgcaag aggcaattgg attccaagac
    45721 ctaaaaaact aagagcagat tcagttaaga tagcattagc aatatttaac gaaccagcaa
    45781 ctacaatagt ctcttttaag tttaaaacta tatgtcttaa tagtatattt ctagtcttga
    45841 taccagtagc tttagcagct agacagtatt cattttcctt tatttttaat gtttcgccac
    45901 gtacaattct tgaaacttcc atccaactta agaatccaat aattagtata atagtggaaa
    45961 ctttaggtgt tagataagta tttaatacaa tcaaaactaa gaaacttggt atactcataa
    46021 gcatatctat taatctcatc aagaattggt ctagcttacc tccaatatat ccactaataa
    46081 cacctacagc agtaccaaat actacagaaa taagcattga taaaatacca acactaagtg
    46141 aaatccttcc accataaaga gctctagaga agtaatctct accaagttcg tctgtaccaa
    46201 agatatgctt taagctaggt tcttgaagtt tagaagtagt atcaattgca ttagagtcta
    46261 tatttaatat aaaagaagct ataattaata tgattattat gctaagagta atacatgcaa
    46321 aagcaaagga tttatctttt tttaattttt ttaagatact tgtaaacaca actagaatcc
    46381 tcctttgcta gattttattt tagggtcaat taataagtat agtatatcag caactaaatt
    46441 acctaaaatt aaaaatagtg ctgataacat agttattgcc ataattacag tataatctct
    46501 tgaaaaaatt gaatcaatca ttaatcttcc catacctggc caagagaaaa ctacttctgt
    46561 aacaaatgca ccagtgacta atttttgtat actcatgcct aggattgtaa ccaatgatgt
    46621 cagtgaattt ttcaagacat gtttaaatag tatgactttt tctgataatc cttttgctct
    46681 tgctgtaata acatattgtt tttttaattg ttcatttaca ctagcttcta cataatttgt
    46741 aaaaatagca gtattatata gacctaaagt tattacaggc aaaactaaat gttttactaa
    46801 gtctccaata ctatcatttc caatagtatg catacctcct gatgggaaaa tgttaagttt
    46861 aactgaaaaa attgaaatga gtatcatacc tatccaaaaa gaaggtatag aaacacctat
    46921 ataattaaaa acagatgata ctttactagt tattgaattt ttatttacag ctaaaaatat
    46981 tccaagaggt atagctacca atattgaaaa tatcaaagaa gtacccataa gaataaatgt
    47041 atttcccatt ttttccataa tttgttctgt aacgggcata tggtttatat aagaaatacc
    47101 taagtttcca cttaaagtgt ttttcaacca gtttaaatat cttatatata ctggtttatc
    47161 aagccccata ttaaccctta tattttcaat atcctgtgaa gacattaaag gatttatata
    47221 tgcatctgct gggtcaccag gagctaattc taaaagtcca aatgataata tagatattaa
    47281 gattaacata ggtattaaaa cttttactct attcaatatt aattttaaca taagtaaatt
    47341 ctcctaatta aaagagatgt ctcgttttaa aataataaaa caatattatt tttagacatc
    47401 tccttttcta attaataata taaaatttta catcaattat tctacataca gtttagacca
    47461 atcttcaaat aatattgcag gagatggttt agcatctttt attcctttta gatttttttg
    47521 agctgccatt aaattttgtt cataatctat agtgtaaata ggcgcatcct tagatatatc
    47581 ctgttgtatt tgcttatata tttcttcacg tttttccttg tttaactcag taaatccttt
    47641 ttcccataaa gcatctattt cagcattaga atatttagtt tggttgcaat attgaccagt
    47701 ttcaaacata cctctatatg ggtttggttc taatccccaa gcataaccat ttacatacat
    47761 atcacattca gtgctattac taaatagtat attgaagaat gccttacttt cataaggaac
    47821 tatttcagct tctataccaa tttttttcaa ctcttgttga gctactaagg catagttttt
    47881 atgcccaaat ctacctgtgt tataacctat ttttaattta tcaattttaa caccactttt
    47941 atccaataag tctttagcct tatttgtatc ttggtcatat ccttcaacac cttcttctgt
    48001 atagaagtct gcttctggaa ctaatataga tttagcaggt acagaacctt cttttccata
    48061 tgctgattct atcatttcat ttctatttaa ggcatatgat aaggcttgtc ttacttcttt
    48121 gttagccatg tttgatatat tttggttaaa tacaatgtag tttaatcttt cttcactata
    48181 agtataagtt tgtaagtttg agtttgattt tgccttttca tatccttcag cagatgtctt
    48241 cataagtgaa atttcgccat tatttaaagc tgcttcttga gatgcttcat taggaattat
    48301 ttttagcgct atagaatctg ccttaggttc tccaccaaaa taatctgcat tcttttcaaa
    48361 tactatgctt tcaccttttt tccattcctt aaacttgaat gcaccagaac caactggatt
    48421 attatttttt tctgacttag ctatatttga ttctccttca aacacatgtt ttggtattgg
    48481 agaaatttta gatataccat ataagaaaga ttcacttgca gttggtaaag taatcttaac
    48541 tgttaaatca tcaatttttt ctactttaac tggtttctca cccaccaata agtattgtct
    48601 tgatggtgaa ttttgttttt cgtctaaaac tgtattaaat gtaaataaga catcttcagc
    48661 agttattggc tttccatcat gccattttaa attggatttt aattttatag ttaattcctt
    48721 actatcttta aaatctactt tttctgctaa ataatttact aaatttcctt tttcataagt
    48781 ataaagagga gcataaacta tatttgatgc aagagagtct tctttaacgt ttgcaaaagc
    48841 tccattgatt atatctgggt cacttgccat aggtattaca acagttccac cagatttgct
    48901 tccactagac ttgtctttat cattggaagc acaggctgta aatgtaagca ttaatgatga
    48961 aactaagatt aatgatgcca attttttaaa tttcatattc ttataaaacc tccataaaat
    49021 aatatttaac acatattttt tattgtataa tagtaatcat tattaaatca atatatatag
    49081 aaattaacta ttatattatt ataattaata gaaaaaaata ataaaatgta agaaaatgtt
    49141 gtaatttaaa tttttataaa atacaatcaa aaggtgtatg ttatcttaag taattttgct
    49201 gagaggagaa aataatgagt aaagcactaa ttgaggttaa agatttaaaa gtttattttc
    49261 atacagataa agggattgta aagagtgtaa atgaagtaag ttttaatata aatgaaggtg
    49321 aaactattgg aatagttgga gaatcaggat gtggtaagtc tgtaacagcc atgtctttga
    49381 tgaagttact tccaacatca aaaatagaag gtggagaaat aatctttcga ggcaaagaca
    49441 ttttaaagat gaatgaagat gaacttatgg gaataagagg gaatgagata tcaatgattt
    49501 ttcaagaacc aatgacatct ttaaacccag cgtttactgt tggaagtcaa atcattgaag
    49561 gtattatgat acatcaagat ttatcaaagg aagaagctaa gaaaaaggta atcgatatga
    49621 taaaactggt agaaatacca agagctgaag aaatatataa ttcatatcca catgaattat
    49681 caggtggtat gagacaacga ataatgatag ctatggcttt atcatgtaat ccaaaattac
    49741 ttatagctga tgaaccaaca acagctttag atgttactat tcaagctcag attttagata
    49801 taatgaaaaa tataaaagaa aaattaaaca catctataat gatgattaca catgatttgg
    49861 gagtagttgc agaaatgtgt gacaaagtat tagtgatgta tgctggcaaa attatagaag
    49921 tggcagaggt tgttgaatta tttaaaaatc caaaacatcc ttatactatt ggacttctaa
    49981 aatcaaagcc tgctcttgga aaaaacaaag ataaaagatt gtattcgatt ccaggacaag
    50041 taccaaatcc aattggaatg ccagattcat gttattttag tgatagatgt gaaaaagtat
    50101 gtgataaatg tagaactcag atacctcctt taatagaatt gaatagtggt catagtattg
    50161 catgttggtt atataaaaag gaggagatat aattgaaaaa agaagagagt ttattaaaag
    50221 tagaaggtct taaaaagtac tttgaagtta aatctggatt atttgataag aaaattaaat
    50281 ctgtaaaggc agtagatgga atttcttttg atttaaaaaa aggagaaact ttggctatag
    50341 ttggagaatc gggatgtgga aaatcaactg caggaagaac cattcttaga ttaattgaaa
    50401 aaactgaagg taaagttgaa tttaatggtg tagatatata taagttagag aaggaagaac
    50461 ttagaaagtt aagacccaaa atgcaaatga tatttcaaga cccatatagt tcattaaatc
    50521 caagattaaa tgtggaacaa ataatatccg aggcagttat agaacataat ttagtgccaa
    50581 agaatgaaat aaaagataat atattaaatg ttgtagaaag ttgtggtctt tctaagtacc
    50641 atttaaatag aaaaccaggt gagttttctg gaggtcaaag acagagaata ggtatagcaa
    50701 gagcattagc attaaatcca gaatttatag tttgtgatga acctgtttct gcactagatg
    50761 tttctattca atctcaaatt ataaatttac ttatggattt acaggataaa tataaacttt
    50821 catatttatt tatatctcat gatttgagtg tagtaaatca tattgcacat agagtttgtg
    50881 ttatgtatct aggttctata atagaaattg caactaaagg agaactttac ttacattctc
    50941 aacatccata tacaaaagca cttatgagcg cagtaccaat acaagaccct acaattaaga
    51001 aaaatagaat tatattaaaa ggagacatac catctccaac aaatccacca agtggatgta
    51061 agtttcatac aagatgccct tattgtaagg aaatatgcaa aaaagagatt ccagttttaa
    51121 aagaaatatc aagaaatcat tttgttgcat gtcatctagt atagatattt caaaaattaa
    51181 atttgatgta tataataaga ataatagaat aaactgaaaa tttttttgat taagatggga
    51241 tttcatgctg ttaatattaa gttagttgat atataagttt aatctataat attattattg
    51301 aaaagagagg tagttatgtc aattttagta acattgttgg gattattggt ttgtacaacg
    51361 atttcaactg tatttagcaa aaagtggagt aatattcctc ttgcaatata tcaaattgta
    51421 ctagggatta tattgtctat tttgccattt aaattctcat tttcatttaa tccagaaata
    51481 tttgtaatat gtatcatagc tccattacta ttcagtgaag gacaaaatgt atcgagaaaa
    51541 gagctattag agcttagaaa accaattttg cttcttgcat ttggtttagt tttaataacc
    51601 gtgtttgcag gtggaatctt tatacatttt cttattcctg ggatgccatt atctgtttca
    51661 tttgctttgg cagcagtaat atctccaact gatttagtag cagtaaaatc aattacacaa
    51721 ggattaaatt ttcctaaaaa tataatgagt atacttgaag gtgaatcttt attaaatgat
    51781 gctgctggag tagtagcatt taaggttgca gtacttgcta cagttacagg agttttttca
    51841 atagaagagg cagggattca atttatgatt acagcttttg gaggaataat agtaggaagt
    51901 attttaggat acataattat aaaaataaga cttagtttac acaagtggaa tttggaagaa
    51961 attccaatgg taatagttat acaaataatg actccacttt ttgtatattt tgtagcagaa
    52021 gaaataggag tatctggaat cctagctgtt gtaatggcag ggatagctca tggaattgaa
    52081 aaagagcatt tacaaaatac aactactaaa ttaaggataa tatcagacaa tacttggtat
    52141 gttttggagt atgtattgaa tggatttgtc tttacactgc ttggtttttt gttaccaagt
    52201 atatatacag gacttagtag taaaaatgaa aatatggcat tggaattgac ttttatttct
    52261 actttaattg tacttatttt atttgttata agatttatat gggtatattt atggcataat
    52321 tcttttataa aacctaaaaa gaatccttta aataattttt ttgtaggttt tttaggtttt
    52381 aaggatgaag aagttataaa agagagtatt tctaaatgta aatactcact aatagttgct
    52441 acttgtggtg ttcatggtac atttacacta gcaactgcct tatctatacc tttttatttg
    52501 gctgataaag atgtatttcc aatgagagat actgttttat ttatatcatc agaagttatt
    52561 cttataagtt tagtattggc aacaatttta ctgccaagat tattaaaaaa taacgtacaa
    52621 gagtcagaac ctttattatc tgataaagag gcatataaac taattttgaa agaagccatt
    52681 ttaaaactta gtaatgaaaa agcacaagaa gtacaaccag ttatacatga tttaaatgaa
    52741 cagttggtag actcagaaaa aggaatacta aatactccag ataataaact tataagtatg
    52801 atgattgcag aagcagacca acagggatta ttagctgttt tgaaactatt agaagatggt
    52861 aaaatttctg atagagcctt taaattgtat agattttata ttacaaaatc aagaaaatct
    52921 gttcaaaaat ctatatttaa aattgtaaaa ttaaaaataa gcatgtggat tataaataga
    52981 aaagtaaaga aagaagtaaa agaaaaaatt acaaaaatag tatctgagaa taaagaaata
    53041 atcaaagagt ttcaccatgc atatgcactt tctactaaaa ctgctatatc atttataaat
    53101 aaaaatactg atgaagataa cagacatgag gccttaatag caatcagatt ctataatcgt
    53161 tatttgaatt ggattactag aaagattcaa aatgatgata agtttgaggc aagagtagaa
    53221 tactacagag taatggcgat acaaagtcaa agagacagtg ttcaacaatt agttgaaact
    53281 aagcaaatat caagagaagt ggctaaagag ttattggaaa atattctcta tgatgaaatg
    53341 atgatgatag aatcataaat ataatggaat aaaatttgat ttttgatgtt aaaattaata
    53401 ctaaaaaata ggaaatagtt ttcaataatt tacttgacat atatatttat ttataataga
    53461 ataaaaccat aaattgaata caatatataa gcattaacaa gctggattgt tactggtaag
    53521 caggcaatac ctaggttaag gtatacaggt gaattgtatc ttaatttagg tattttttta
    53581 tgaataaggg aaattgtatt ttgggagaga tattgattat gattattcaa caaatttata
    53641 ataataatgt tgtattagtt ttagatgaaa atataaaaaa agaattaata ttaacaggat
    53701 gtggaattgg gtttcaaaaa aagaaaggtc aagaaataga taaaagtaaa attgaaagaa
    53761 cttttgtaat acaagatgaa agctttttag ataaaattag taaactagca agccaggttg
    53821 atgagaaatt ttttgaggtt agtactgaaa taattgctta tgcagaggag aacttgaata
    53881 ctaagcttta tgaatatatt tatgtagcac ttactgacca tattgcattt gcaattaaaa
    53941 gatatcatga aaacataact ataaagaatg atttactaca tgagataaaa agaatacata
    54001 aaaaagaata tgagattggg aaatgggctg tagattatat aaataaagaa tttgatgtga
    54061 aatttccagt agatgaagct ggttttatag caatgcatat agtaaattca aactataagg
    54121 gaagttcaaa ggaatcacta ttaattacta aaattgtaaa agacatacta aatattataa
    54181 gatattatta tagagttgaa tttaaagaag atgatataaa ttatgatagg cttctgactc
    54241 atttaaaatt ctttgcaaaa cgattagtaa aaaaagaaaa aatcaatgat acaaataatg
    54301 aaattataga tataattaaa gtaaagtatg aaaaggatta tgattgtgca tataaaataa
    54361 aaactcatgt agaaaagaat tatgattact atgtaagtca agatgaacta ctttatttaa
    54421 cattacatat caaaagagtt atatctgtac tgaatttata ataaagagta gtttaataca
    54481 gaatgtatag atttaatata ttatgtttaa ttttaatata ttatttaaaa tttaatataa
    54541 aataataatt ttaaaacatt aagattgtta ctgataatgc aggcaagact tatgtttata
    54601 aaaaaattat aatagtttat ttttaattct gaaattaggt taatataggt ttatttatat
    54661 taacataagt ttaattttag aattaagtat actaatgtaa ctttttataa acttaagtct
    54721 tttttattta aaaaaatata aaataataag gagagaaaag taaatgaaaa aagtatttgg
    54781 tgttttacaa aaagtaggaa aatctctaat gctaccagtt gcattacttc ctgcagcagg
    54841 tatattactt ggcgtgagta atgctttagc aggagacgca ttgttggctc attttccagc
    54901 tttggcgaat cctacatttc aacttataat aagtataatg gaaagttcag gtcaaattat
    54961 atttaataac ttaccactta tatttgcagt tggggtagct gttggtttaa ctgaaggaga
    55021 aggtgttgca gcattggcag ccatagtagg ttttttaatt ctcaatacat ctatgggtgt
    55081 tatggcaggt gttacagaag atatggtaga caattctatg tatgcaaata ttgttggaat
    55141 accaacaatt caaacagggg tatttggtgg cattattata gggatagtgg ctgcttatct
    55201 ttataaaaag ttttataaaa ttgaattacc tcagtatcta ggtttttttg caggtaaaag
    55261 atttgtacca atcgttactt cattagttgc tatagcaata ggaattatat tgtcttttat
    55321 ttggcctcca atacaagagg gattacttag tttctcaaaa aatgttatag aagcaaatca
    55381 aacactagca gcatttatgg aaggttcttt ggaaagacta ttaataccat ttggtttgca
    55441 tcatgttttc cataatccat tttggtatca atttggagaa tatgtaaata aagctggtga
    55501 gcttgtaatg ggtgaccaaa agatattctt tgctcaactt aaagatggag taaatttcac
    55561 agcaggtact tttatgacag gtgcatttcc atttatgatg tttggtcttc cagcagcagc
    55621 tcttgctatg gtgcatgaag caaagccaga aaagaaaaaa tttgtagcag gtataatggc
    55681 atcagcagca ttaacctctt ttttaacagg aataaccgag ccaatagagt ttgcgttttt
    55741 atttgttgca ccagtattat ttgcaataca ttgtttattt tcaggtttat catacgcaat
    55801 tatgcaatta ttaggagtta aaattggatt cacattttca ggaggattaa tagatttctt
    55861 attatttggt gttcttccta atagaactcc atggtacttg gctatcttgg taggtattgg
    55921 ttttgcagta ttatactata gtgtatttag atttatgata agaaaattta atttaaagac
    55981 accaggaaga gaagatgagt cagaaactaa cgctgaagtc attgaaatgt ctaagaatga
    56041 attagcatca gagattttga ttgctttagg aaataaagac aatttaaaga gcctagatgc
    56101 gtgtataaca agacttagat tggttgtaaa tgatataaat aaagtagata aagaaaaatt
    56161 gaaatcactt ggagcagcag gtgttatggt tattggcaac aatgttcaag ctatatttgg
    56221 accaaaatcg gattcaataa agtctgatat aaaagatata atagagggaa aaacaaaggt
    56281 tgaaagtact gttactaaaa atgttgataa aaataaagtg aaaaaaaata tggaagttgc
    56341 aaatatggaa aatgctttag tagaaaagat tgattcatta acaaatggag agatattaga
    56401 tatagaagaa gtgccagatt ctgtattttc aagtaaactg atgggggatg gatttgcaat
    56461 taaatctagt gatggattga tttattcacc agttgatgga actattggag ttatatttcc
    56521 aactaagcat gcaataataa taaaatccca aaaaagtgga gtagaaatac ttatacattt
    56581 agggatagaa actgtaaatt tagaaggaaa tggatttgaa gtatttgtga atgtagggga
    56641 tgaagtaaaa gcgggagaaa aattagttaa aatggactta gaatatattg aaaaaaatgg
    56701 tctatcaaca ataagtcctg tagtatttac gaatttagaa caaaatcaga aattaagcat
    56761 taaaaaagga gtaagcacag caaaagagga gaatagagta agtatattaa gagatgatat
    56821 tgaaaaaata ggatagctat atgatagtgt aactaaaagt tatgtgggat ttaataaata
    56881 tataaatagg ttcagttaac atgcaattta tttaatatat attttaagta atagaaatat
    56941 atatcattat attttgatat attttaaaac attaaaaaac ttgaggtatt agtaagataa
    57001 atacactaat acttcaagtt ttattaaaat aaaatttaca taaattatct attcatctaa
    57061 aagagtaata tccaaaggat ttttattgtt tatataattt ttaggagata ccccgtagtt
    57121 ttttttaaat gcccttacaa aactagaata atcgttgaat ccacatttat tacaaacttc
    57181 actcataagg tgaccattgg ttattagtga ctttgccaaa attaatcttt tttgaactat
    57241 ataattgtgt atagacgttc cagtatgaga tttaaatttt ctcataagat aatacttact
    57301 tataaaaaat tcagacgata tgctatctat tgaaagctta tcatctatat ttgaatttat
    57361 atagtttaat actttcttaa tagtttcatc ataaaaaaca tcttctgttg attccatatt
    57421 ttcatttttt aggaaaattc tgtttaagaa tatcataagt tgtataaata atgcatttct
    57481 caatatttca tttccaaatt cagtattgga ttcggaaata tttatttgct caataaaact
    57541 cttaatagat tcaatatcat gtatatttaa acgcaatcta ttgcatttat tctctgtagc
    57601 tattttaaaa catttttcta agtcactact agcatcacta ttttttttca taaattctgg
    57661 gctaatccat attgcaattc tctcataaaa gacatttgaa tctataactg gtttatgtat
    57721 ttcattattg ctgataaaga gtatatccca aggctttagt ttatagggaa taccatcaac
    57781 aaaataagtt acatttccat ttataaatat aattatctta ttaaaatcat gattatggta
    57841 ttcaaattgt atatcttttt tatctctaat attaaatatt ttaaagttat cgtttaagta
    57901 cccgatttta ttatccatag tttttataga agacctttcc tcagttatat tatagaaaat
    57961 tatagagcat tttttgcaat gtttcaagca tttttaacca ttcacatagt aaaaaattct
    58021 taatataata ttatatgtag tgtaatttta gcagaaagag tttaaaggga ggaaagcatt
    58081 tatgaaatta aatgatatta tacaggggtt ggatataatc aatatcaagg gtgaattaaa
    58141 tatagatatt aataatgtac aatatgattc aagaaaggtt acaaaaggta cattatttat
    58201 atgtataaaa ggatttgtgt cagatggtca taagtatata aaagatgcca tagaaaaggg
    58261 agcaagtgca tttcttgttg aagaagatgt agaaataaaa ggatgtacat ttataaaggt
    58321 aaaagataca agaaaagata tggcaaaagt agctgataat ttttacaatc atccatctca
    58381 aaaatttaac gttataggag ttacaggtac taatggaaaa actagtataa ctactatact
    58441 aaatgagata ttaactttaa ataagaataa agttggactt ataggaacta taaaaatttt
    58501 tgatggagaa aaagacattg tttccaattc aacaactcca gaaagtatag atttacaata
    58561 tcattttaat aatatgttgg ataatggatg tgactactgt gcgatggaag tttcatcaca
    58621 ttcattggca ttaaatagag ttgatgaaac agactttaaa ctaggcatat ttacaaattt
    58681 aacaccagac catttagatt ttcataaaga tttagaggat tatagaaaag caaaagaaaa
    58741 attatttttt aagactacta tggcaaatat aataaacata gatgatgaag gtggaaaaaa
    58801 gatatatgaa aatataaaag gtataaatgt accttgttac acttatggtg ttgatactaa
    58861 ggctgatttt atggctagag atataaaatc agattcggat ggagtatctt atagattaat
    58921 aacaccttca tatgaagaag taatatttat accagttcca ggaatgttta cagtatataa
    58981 tactttagca gttatagctg cttgctatgt acttggcata cctaaaccaa tatataaaga
    59041 aggccttaga ctttctaatg gagtatcagg aaggtttgaa acagttccaa atgataaagg
    59101 tataagcgta attgtagact atgctcatac tcctgacgca cttgaaaatg tactaaagac
    59161 aactcaacaa tttgcagaag gaaaaataat ttctgtgttt gggtgtggtg gagatagaga
    59221 tactgaaaag agacctttga tgggagcaat tggacaaaaa tattctgatt tatgtattat
    59281 aacttctgat aatccaagaa ctgaagaacc agaggcaata ataaaagata tacttgaagg
    59341 aattgacaag aaaaaagaaa attaccatgt tgttgttgat agggaacaag ctatagcaga
    59401 agctataagt atggcaaaaa aggatgatgt tgtaattata acaggtaagg gacatgaaac
    59461 ttatcaaatt ataggtaaag ttaagcatca ttttgatgat aaagaagttg caaatgagtg
    59521 tttaagtaag atgtagcata aaaattaaac aaaatacaag aacaaaaatg taatatcaag
    59581 cttcactttg atattacatt tttttatatg taaataattg taaaatagat aatgcaataa
    59641 tataaacact aatatctata ttaattaatt tattgttgta ataaagttta taattttgta
    59701 taattacagt aaatatggaa aaataagtat tattataaaa tgtttacaat aattgtcata
    59761 agataatgat tatacataca tagattcgag aaaggcagga agcataatgt taagtgatgc
    59821 aaaaaataat aggtatggtt tgtccataat tgctgtcata agtatcttag taattacaat
    59881 ttcctgtttg atttatggtt caaggttgaa taagacatta ggtgaagaaa cgaatcaata
    59941 tctttcagaa atagcaaatc aaagtgtcaa tgtgttaaaa aaacaaatta atggagatat
    60001 aaagttacta gagtcaattt caatatttat tgaaggagaa gagtcttttg aagtagataa
    60061 tatcctttct atactaaaaa gacaagctat taatagttca tttaaaagaa tgggagttat
    60121 tttaccaaat ggtacagcat acactacaga tggttatata gaagacttct ctaaaagaga
    60181 ttatttctta aaatcaatgc aaggagaagt ggttataaca ggcaaattaa aagatgtaat
    60241 agaagatgat aaaaatacca atagtaatat taatgtatat tctgtaccaa tttataaaga
    60301 taatgaggtt aaaggagtta tatttgccac acatagtacg aagttgtatg aaaaaatact
    60361 ttctgtacct acatttaatg gaaaaggata ttcttatata actagaagta atggtgatat
    60421 tgttttaaat ccaagcagta aaaacgccaa ctctactaaa gaaaatttat tttcttacat
    60481 tggcagaagt gattcaatat caaaatctag tatcaacaat atgaagtcaa atataaaaaa
    60541 ctttaaatca ggttcattaa gttatagtat gtttggaaaa ggatattatt taagttatgc
    60601 cccaatagga atcaatgatt ggtatctttt ttctgaagtt cctaaaactg ctatatctga
    60661 gaaatcatat gctattataa aacttacatt atcagcatgt gtagtcttga ttataatctt
    60721 tacggcatta acaatttata tactatttat acataaaaag agtaaggaaa aattggaaga
    60781 atttgctttt aaagataacg ttacaggtat tggcaattca aataaattta atcttgaagg
    60841 gggaaaattt ttatcctctc atgagaaaaa gaatctagtt ttaatttatt ttgatataga
    60901 taagtttaag ctagtaaatg ataggtttgg gtatgaagaa ggagatagag tattaaagga
    60961 aatagcagag ataattaaga atatatttaa agagcaatct gtattttcaa gaatttcaaa
    61021 tgacaatttt gctataatat ttgaaaagaa aaataataga gagtcaatta tagaaatatg
    61081 tgaacttata cgtaaaaaat tgtcaatgat aaaaacaagt ttgggagtag aactcaattt
    61141 aattccatcc ataggtgtat attttgttga agagggagaa acaaatattt ctacctgtct
    61201 tgacaaagct atgattgcaa aaactacagt aaaaagaaaa tatttaaaag tttatgagat
    61261 ttatgctgaa aatttaaaag aaactctcat agaagaacgt gatattgaac aagaaatgca
    61321 tgatgcttta aaaaatgaac aatttaaagt ttatttacag cctaaggttg atttatcaac
    61381 tactaaaatt gtaggtgctg aagcacttgt acgttggcaa catcctaaaa aaggtctaat
    61441 aagtccaggt gtatttattc ctatttttga gaaaaatggc tttataacag aattggatat
    61501 gtttgtattt acccaagttt gtaaaaattt taaacgttgg gaaaatgaaa atttccccac
    61561 atttcctata tcaataaact tatcaagagt acatcttgag aatccaggct ttatttctga
    61621 gcttgaaaga ataacaaaag aatatgaaat tgaaccaaat ttaattgaga ttgaattgac
    61681 agaaagtgca atatttgaca atacaaaaat attatttaaa ataatgcaaa ctttgaaatc
    61741 tgttggattt aaaatttcta tggatgattt tggttctggt tattcttctt taaatatgct
    61801 taaagatatg ccaattgatg tattgaaatt agataggcaa ttctttataa cagtgggaaa
    61861 tgcaaaaaag agtcaaattg tagtttcaag tattgttcaa atggcaaagc aacttgatat
    61921 aaaagttgtt tcagaaggtg ttgaaactgt agagcaagca gagtttttaa ggtttatagg
    61981 ttgtgatatg gcccaaggat ttttatttgc tagaccaatg ccaatagaag aatatgaaaa
    62041 attaatatta gatagatata gtttaaatag aaaagaaaca aattaaataa aattgtgaat
    62101 tataacataa aaatttataa aaaagtgaac tttgttaatc aatgttcact tttttatgta
    62161 aaaatatact attataaaaa cataaatcat tgttaggata ttattttagg aattattggg
    62221 caaagtttat taatatgtag tattttttac atttgaatgt ttttgaggta agagtatatg
    62281 ggattatagc aaaatacttt agatagtaat aatagtaatt tctataggtg tgttatacat
    62341 attttaaaaa ataaaaatat aatttataaa tttaaatgtt atatatgtaa gtaattttat
    62401 tatatcaaaa aaagagtttt tcataatcat ttat
//
LOCUS       DAJMZY010000008        60710 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.008, whole genome shotgun sequence.
ACCESSION   DAJMZY010000008 DAJMZY010000000
VERSION     DAJMZY010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 60710)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 60710)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..60710
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.008"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            <1..606
                     /locus_tag="OE968_000482"
     CDS             <1..606
                     /locus_tag="OE968_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HCP7217799.1"
                     /translation="ISGYLTKKLQDLNVDTIRTDILTSPTVTDVIVWNIEQSGTDTFS
                     ATYEVDQQIKEGEQTTTVKATYTVKVHVDADRDMVIIQNPTLAPAIEKSDYEPKTPEA
                     DASVDADTVNDATAFLETFFKLYPTATAKELAYYVFGNVLEPIGRDYLYSELVNPVLT
                     KDGDNMKVKVAVKFLDNQTKATQVLQYELILHKDSNWKIIM"
     gene            819..1676
                     /locus_tag="OE968_000483"
     CDS             819..1676
                     /locus_tag="OE968_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002585362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HCP7217800.1"
                     /translation="MYKEVGISSNNVPITLSIWYTERSSPTIVFLPGTMSHPLMYENF
                     LCGLSERGFNIIGIHYLSHGKSPKIKKNYTMEDLLHNVYDATTYGIENFGENIAVMGS
                     SQGGILAAMAAGRDTRLKAVFPHNIMLTTLKETMSLTKYPTWSHRFMGLIQWGFRVGG
                     KLLPNYKVPGDAYLDYDRVFYSEQAKQDCLNDPMLLPYYPLRFVTSLFNADLSCLENG
                     AIQCPVILITAKGDPLFSFDYTNKVFDLIHVPQKELLALELNRHMIFNEDTDTTINAL
                     EATLHKYLG"
     gene            1754..2335
                     /locus_tag="OE968_000484"
     CDS             1754..2335
                     /locus_tag="OE968_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCP7217801.1"
                     /translation="MPRFTEQEKEIINSKLLIEGEKLFALHGLKKVTVDDLVAAVNIS
                     KGSFYAFYPSKEHLYVEINFRLQKELFTSIETTIKKKKYKNHRDLAKDVIMLSLTGVI
                     TSPILSQIDLSLMDYLQRKISSDIFENHMYSDIRILEILEDLGVVFLVPHTVIIKSLY
                     SVLSCLEQFKEDEELNMIQNLLVNGIIQQVVAE"
     gene            2439..3284
                     /locus_tag="OE968_000485"
     CDS             2439..3284
                     /locus_tag="OE968_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCP7217802.1"
                     /translation="MIDVKKLYFSYTDKPFVENVSFHVGRGEIFGFLGPSGAGKSTIQ
                     KVLTGLNTRYKGSVKVAGTEIREHTNQFYENIGVDFEFSTCYEKFTARQNLAYFASLY
                     EKQPRSIDELLHMVGLENDGDKKVADFSKGMRSRLNFIKALVHDPDILFLDEPTSGLD
                     PTNSRLMKDIILAEKKRGKTIIITTHNMFDATELCDQVAFIVAGKVSALDSPHNLIMS
                     RGAAKIQYTYYDKGEKTGECLLDRTTEDKLLKSLISENRLLSIHSSEPTLNDIFVDIT
                     GRTLQ"
     gene            3281..3964
                     /locus_tag="OE968_000486"
     CDS             3281..3964
                     /locus_tag="OE968_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016295773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCP7217803.1"
                     /translation="MRLGRLICGDIHFQWKYGFYFIYFILTVLYVCGIAALPEHWKTD
                     IASIMIYSDPAAMGLFFMGAIVLLEKSQKVLNAMVVSPVKISEYILSKTVALIAISTV
                     IALILGVVSGSNHLLGIAVGTALTSAIFTMLGIIAATKISNLNQFLIVIMPIEIICFV
                     PPIVGLFVKLPYLFRFFPFTACMNLITGKSVLLSFDMVLVIATLIILYIVARHTVEHM
                     WKSLGGVKL"
     gene            3961..4659
                     /locus_tag="OE968_000487"
     CDS             3961..4659
                     /locus_tag="OE968_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002583502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCP7217804.1"
                     /translation="MKKILSSTIQIFKQIKSDPMMFAACFSPFIMGTLIKFGIPFLER
                     ITKFSLQAYYPIFDLLLSIMAPVLLCFAFAMITLEEIDDKVSRYFSITPLGKSGYLFT
                     RLGVPSIISAVIAFIVLLLFSLEKLSIGMTICLALLGSVQAIIVSLMIITLSSNKLEG
                     MAVTKLAALTLLGIPAPFFIDSYYQFAVGFLPSFWVAKAMQNEAVLYFSIGLVVALVW
                     YYFLTKRLFRKLAG"
     gene            4671..5582
                     /locus_tag="OE968_000488"
     CDS             4671..5582
                     /locus_tag="OE968_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HCP7217805.1"
                     /translation="MEKGRLLQNKNMNKAIQVSKITLIINLSLSLLKFAAGYIGKSSA
                     MLSDAVHSASDVVSTIVVMVGIKISEKQPDREHPYGHERMECVASIILSVALAITGAG
                     IGYSGIKKIFSGQYNTLSVPSGIALTAAVLSIVIKEWMYWFTRSAAKHTNSDALMADA
                     WHHRSDALSSVGSLIGILGARLGYAILDPIASVVICGCILKAALNIFKESINKMVDHS
                     CDNATETRIREVVLQQQGVDGIDELKTRMFGAKMYVDIEILADGNLALYDAHRIAEGV
                     HQTIENNFPQCKHCMVHVNTNELLYSA"
     gene            5634..5774
                     /locus_tag="OE968_000489"
     CDS             5634..5774
                     /locus_tag="OE968_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016295776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7217806.1"
                     /translation="MEQYWWIIIVVVLIVVGLLKIVIMKKYNQRRNSNNRSKDSEDDK
                     MY"
     gene            6065..6691
                     /locus_tag="OE968_000490"
     CDS             6065..6691
                     /locus_tag="OE968_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCP7217807.1"
                     /translation="MSDTKENILKIALHLFAVNGYEAVSVSMIAEALGMTKGALYKHY
                     KNKQDIFDCIVERMYQIDNKRAKDYQVPESTIEVTPNAYRNTTIGSLITFTLAQYDFW
                     VTDEFASNFRKMLILEQYRNLKMNMLYQKCLVNGPISYIEDIFNEMIEKGVLQECDTK
                     QLAIEYYAPLFLLISVADAVENCWDLKTQLTTHVKQFVKKYIINEKVK"
     gene            6813..7529
                     /locus_tag="OE968_000491"
     CDS             6813..7529
                     /locus_tag="OE968_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HCP7217808.1"
                     /translation="MEYIRSKKYFTPDLQTKIMGPNPIKLQEELLQNHKIPSGSYVCD
                     LGSGQGLTSVFLAKEYGFVVFAVDLWSEPKENEEFFKKMGLSSAQIKSVKADANELKF
                     EKEFFDAVVSTDSYNYFGRDPIYLDEKLLPFVKKGGFVYITVPGMKKDCHEKLPEELL
                     LSWTPEELDYIHDITYWSNIISHCKKADLISIYEMESNSEVWSDWIKQNNEYAINDRK
                     AIEAGGGDYLNFIAIILQKK"
     gene            7679..8275
                     /locus_tag="OE968_000492"
     CDS             7679..8275
                     /locus_tag="OE968_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015541496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HCP7217809.1"
                     /translation="MKILWIIIIMADNLLPLLLARFYPNYKHKEMALSVLGSRQSPVK
                     WIYNVWCIISGVVFCIAPYALYQENDSGWAIAIWMLLAIYGIGCEIISGVCPLNENRQ
                     DEDIITKIHGGTSAIGFMALLVVPLLFAILQFQTTKVVLGAISLVCFTIAFIFFCFFI
                     MGEKEKFANTVLRYGGLWQRLVLISCYIPLFVWSVSNQ"
     gene            8362..8553
                     /locus_tag="OE968_000493"
     CDS             8362..8553
                     /locus_tag="OE968_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003064779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4177 domain-containing protein"
                     /protein_id="HCP7217810.1"
                     /translation="MKKYEYVEINYNAKGVVFLCTDKHKEIIDSYAKTGYHYAGFVPT
                     EIDAKGCMRKIDLIFEKED"
     gene            8577..8807
                     /locus_tag="OE968_000494"
     CDS             8577..8807
                     /locus_tag="OE968_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7217811.1"
                     /translation="MIGLKRRDMNYIMKVGAKAQGVSVSEFRAMLQDTIDKTMESTDP
                     DVQANFKRYFGNKRPTPEEYIYTITKKTKVKV"
     gene            9074..9493
                     /locus_tag="OE968_000495"
     CDS             9074..9493
                     /locus_tag="OE968_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009261829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HCP7217812.1"
                     /translation="MKPSDFQKTIQCQFECKLKKVVKGIIWNYRKELKRRKNKEISFS
                     ELPDITVESLATWDDYETNYTIFNVCGIDIKVLDDELAEALKQLPEKKRNNVLMYYFL
                     EMSDTEIADIMNYTRGAVFKHRHRALETMKEILKEKK"
     gene            9496..9750
                     /locus_tag="OE968_000496"
     CDS             9496..9750
                     /locus_tag="OE968_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCP7217813.1"
                     /translation="MKKKYKHPSYYLISSAMDGDETAIEKLLAFYDPYISKCCLRPLY
                     DEYGNVYIVVDMELKGRIREALIKMILDFEIDIDIETEEE"
     gene            10125..10328
                     /locus_tag="OE968_000497"
     CDS             10125..10328
                     /locus_tag="OE968_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HCP7217814.1"
                     /translation="MNNTDVPIWEKYTLSIEEASRYFRIGEKKLRKLAEENLDSGWVI
                     VNGNRIQIKRKQFEKIIDTLDEI"
     gene            10406..11596
                     /locus_tag="OE968_000498"
     CDS             10406..11596
                     /locus_tag="OE968_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006354938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HCP7217815.1"
                     /translation="MSKMKRQDSKGRNLRLGESQRKDGRYVYKYTDIFGKPQFVYAWK
                     LVPTDKTPTGKRDDKSLREKEKQIKKDLDDGIDTIGGKMTVCQLYAKKNNQKKNIKRN
                     TEIGRQYLMNALENDPLGMRAIDTVKQSDAKEWAIRMNDKGYSYKTIDNYKRSLKASF
                     YMAIQDDCIRKNPFHFKLSDVLEDDTEPKVILTPEQEEKLLSFMETDNVYSKYRDEVI
                     LLLETGLRISELCGLTTHIDMLNRVINIDHQLLRDTEVGYYISTPKTKNGKRELPLTE
                     RAYQALERILKNRGKAQPLVVDGYSNFLFLNREGLPKVAGNYESMVRGLIKKYNKTHE
                     DKLPNITPHSFRHTYCTNMANKGMNPNTLQYIMGHANITMTLGYYAHGTFQSAKAELE
                     RLAS"
     gene            complement(11853..12653)
                     /locus_tag="OE968_000499"
     CDS             complement(11853..12653)
                     /locus_tag="OE968_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCP7217816.1"
                     /translation="MRLNKRSEGYINYVKGVKREKRNVLFYQLLILIGFIVIWELLAD
                     LNVINTFLFSKPSDIYNLFIQYAFSGQLFKHIGISVYETVLGLVIGTVLGILVAIALW
                     WSEKLSKILDPFLVVLNALPKTALAPIIIVWVGAGIEGIVVTAVTISVVVTILSAYNY
                     FMNIDEEKIKMLKSFGATKSQILFKLILPANTGNLINLTKINIGMAWVGVIVGEFLVS
                     RYGIGYLIVYGSQVFKLDLVMMGVFVLAICAWAMYAVVNIIEKIYNSR"
     gene            complement(12848..14446)
                     /locus_tag="OE968_000500"
     CDS             complement(12848..14446)
                     /locus_tag="OE968_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HCP7217817.1"
                     /translation="MKAAIYSRKSRFTGKGDSIENQIQLCIDYAKSIGVKDFLIYEDE
                     GFSGSNIDRPQFKKMMQDAKDKKFSYLVCYRLDRISRNVSDFSTLIEKLNELSISFIS
                     IKEQFDTSTPMGRAMMFISSVFAQLERETIAERIKDNMYELARSGRWLGGNTPHGFNS
                     EKITFLDENLKERSMYKLQVNDEQMEIVKLIYNKYLELRSLSKLYKYVYNNGIRGPRG
                     GKFDPSSLSRILRNPAYVKANDEILDYLKNSGMDVVGTPDRKCGILTYAKNTSNSIAA
                     IAKHHGVIEPEIWLEVQNQLDKNRDKTPRISTGKTALLSGLIKCGKCGSNMRITYKGK
                     KTDKDLKYYYICGTKKTLGSDSCNCKNLNGPLVESLVIDKIKNCKEESIISAFNSNNI
                     KTDNVFNIFKSETNLLKNQILDKERLIKNLVIELAKNTGSTASDYIVSQIESLNNEIS
                     ILKDKINILESSNINISSDSINIDIIVSNLKRFNDEVDNASLDDKRLLLSTIINSIVW
                     DSSLGNLNIVYMGAEVDNSVSLSN"
     gene            14774..14950
                     /locus_tag="OE968_000501"
     CDS             14774..14950
                     /locus_tag="OE968_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7217818.1"
                     /translation="MEINVIEIFPKDKAKLNKIEMDKASWFVNIISKKYPKEALNEAF
                     STLEKELNISKANT"
     gene            15124..16254
                     /locus_tag="OE968_000502"
     CDS             15124..16254
                     /locus_tag="OE968_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003462216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HCP7217819.1"
                     /translation="MNNFEIKTRIKFGEGSLKALQELKNKNVLIITDPFMVKSKTIDK
                     ITSNLINSTYQVFEEIVPDPPIEVVVAGIEAFKSINPDVIIALGGGSAIDAAKSIMDF
                     SKKILKINEVEFIAIPTTSGTGSEVTSFAVITDSQKKCKYPLVSDDLLPDMAILDPEL
                     VKTVPNFITADTGMDVLTHAIEAYVSTNSNDFSDALAEKAIKLVFKYLIKAYKDGNDI
                     EAREKMHNASCLAGMAFNQASLGINHSIAHVLGGKFHIPHGRTNSILLPHVIEYNSSI
                     VGYTNTTYSATAKKYAQIAELVGLGSANIRISVRNLVNEIKKLQKEMNMPTKLTQCKL
                     SLEDITNEEREIAKLAIKDTCTLTNPKVPTEDDIINILKNIK"
     gene            16495..16845
                     /locus_tag="OE968_000503"
     CDS             16495..16845
                     /locus_tag="OE968_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003453843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMC domain-containing protein"
                     /protein_id="HCP7217820.1"
                     /translation="MTEESKQRVIQEYVPGKQVTLAHIIANPNEDIYKKLGLVLDKKD
                     AIGILTITPSEASIIAADVATKASNVSLGFIDRFSGSVVISGDVSSVESALNDVLEVL
                     GNMLNFSSTKITRT"
     gene            16853..17302
                     /locus_tag="OE968_000504"
     CDS             16853..17302
                     /locus_tag="OE968_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EutP/PduV family microcompartment system
                     protein"
                     /protein_id="HCP7217821.1"
                     /translation="MKNIIFMGKTGSGKTTLCQKLDQLELKYKKTQSVELYNNAIDTP
                     GEYMENRNLYNALITTSADAKIIAIVYDATQEENYIAPGFASMFCKDVIGIITKINKA
                     TENEVNIAYERLSLAGASQIFKIDTVDNIGLEKLFKYLEKYKNIDEV"
     gene            17404..17979
                     /locus_tag="OE968_000505"
     CDS             17404..17979
                     /locus_tag="OE968_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HCP7217822.1"
                     /translation="MGKKILLVDDEPLLRMDTKDILESHGYEIIGEASDGFEAVEMCK
                     KHKPDLVIMDIEMPILDGIKAGKIICKENIAGGVLLLTSFEDKEYVEKAKSIGAYGYL
                     VKTASEKSLIPTIEMCLNKVNEFEKMKKDLEKVNSKLNERKLVERAKGILIREFKISE
                     DEAYTRIRKLSMDKRTTMMEIAKMIIIGYDD"
     gene            17972..19381
                     /locus_tag="OE968_000506"
     CDS             17972..19381
                     /locus_tag="OE968_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase N-terminal domain-containing
                     protein"
                     /protein_id="HCP7217823.1"
                     /translation="MTNTIKKISTAQTYLNNNEIEKIIEVSKSLDLMASFYEADVFID
                     VLSKFDDEAIVVAHGRPKEKSMYCENVIGKKALIENEPGVIKCLKTGERVRDIKALTQ
                     EYKLVKQNIQPITLDDKVLAVLIVEKDISSEVKNEFNASEDEENKNLHQFIKLIGNND
                     FLVDNLNSAILIFDKNGKLKIKNRIATEIYKNLGFGYDIQDMHYNDLDIETNTFENIL
                     MDENYDETNEVSIGNMFFKIKTIYIKDDEFKVCKIVQDISDLKRKEEELVLKTVAIRE
                     AHHRVKNNLHTVISIIKKQSRLSQNDEVKQCLDNIINRVFAILSTHYLLSKEVDNNIS
                     IREGINLLVSNIQGGYLFSKDIDIRITGEDFKISGEKATAILLVINEILQNCYDHAFS
                     DREHGTIQILINKDNDYRNIAIIDDGIGFDSNNINKNSLGTYIIDSYITQMLKGNIER
                     KSSENGTEVLITIPTQINI"
     gene            19565..20998
                     /gene="eutA"
                     /locus_tag="OE968_000507"
     CDS             19565..20998
                     /gene="eutA"
                     /locus_tag="OE968_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004458698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase reactivating factor
                     EutA"
                     /protein_id="HCP7217824.1"
                     /translation="MREELLSVGIDIGTSTTQLIFSKLIVENTESNFSVPRISIVDKE
                     IIYKSKVYFTPLISNNEINGQQIKDIVENEYKKANISKEDIHTGAVIITGETARKENA
                     NDVLHTLSGFAGDFVVATAGPDLESIISGKGAGAHIYSKEHSTTIVNIDIGGGTSNIA
                     SFKRGEVTDTGCLDIGGRLVKIDKISKKITYISPKIDKIIKDNNLNLQVGTMATVENT
                     KPIVDIMVDLLMESIGLKKQTPLFDFIITNKSISIDENIKNVSFSGGVADYIYYDGEI
                     KDYFEYGDLGILLGQAIKNCEYLKKVNVVKSMETIRATVVGAGSHTTEVSGSTITYTS
                     EKFPLKNLPVLKLSIDEETGTSKQISEAIKNKLNWFKLENDLQKVAIAMIGKKNPTFL
                     DIQEYAKGFVDGMQQIIENDLPFIVIVENDMAKVLGQAIYALLNYEKEIVCIDSVKVE
                     NGDYIDIGKPIVEGKVLPVVIKTLVFN"
     gene            21016..22380
                     /locus_tag="OE968_000508"
     CDS             21016..22380
                     /locus_tag="OE968_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003454054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase subunit EutB"
                     /protein_id="HCP7217825.1"
                     /translation="MILNTKLFGRTYQFKGLYDVMAKANEEKSGDKLAGLAAESAEER
                     IAAKVVLSHIKLEDIRNNPAVAYEEDEVTRIIQDAVNEKVYEEIKNWTVSELREWLLD
                     SNTTSLDIRRISRGLTSEMIAAVAKLMSNMDLVYAAKKIKVTAHCNTTIGEQGTLSAR
                     LQPNHPTDDPDGILASLLEGLTFGIGDAVLGLNPVDDSVESVTKVLKRFEEVKQKYQI
                     PTQTCVLAHVTTQMEAIRNGAPADLIFQSIAGSEKGNEAFGFNGDTIEEARQLALKHG
                     TATGPNVMYFETGQGSELSSEAHHGIDQVTMEARCYGFAKKYEPFLVNTVVGFIGPEY
                     LYDAREVVRAGLEDHFMGKLHGLPMGVDVCYTNHMKADQNDMENLAILLTTAGCTYFM
                     GIPHGDDVMLNYQTTGYHETASLREMFGLTAIKEFDAWMEKMGFSKDGKLTELAGDAS
                     VLLG"
     gene            22393..23274
                     /gene="eutC"
                     /locus_tag="OE968_000509"
     CDS             22393..23274
                     /gene="eutC"
                     /locus_tag="OE968_000509"
                     /EC_number="4.3.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014952556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase subunit EutC"
                     /protein_id="HCP7217826.1"
                     /translation="MNEKDLKALVEQLVGQMLGELDTNVVSETVKKATEVVVDNNACI
                     DDITEVDIRKQLLVKNPKDAEAYLDMKAKTPARLGIGRAGTRYKTETVLRFRADHAAA
                     QDAVFSYVDEEFIKENNMFAVETLCKDKDEYLTRPDLGRKFSPETINNIKSKFGTNQK
                     VLILVGDGLSSAAIEANLKDCVPAIKQGLKMYGIDSSEILFVKHCRVGAMDHLGEELG
                     CEVICMLVGERPGLVTAESMSAYIAYKPYIGMAEAKRTVISNIHKGGTTAVEAGAHIA
                     ELIKTMLDKKASGIDLK"
     gene            23294..23947
                     /gene="eutL"
                     /locus_tag="OE968_000510"
     CDS             23294..23947
                     /gene="eutL"
                     /locus_tag="OE968_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003761789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutL"
                     /protein_id="HCP7217827.1"
                     /translation="MKNDVIRPNILGIKIISNISPEMAQKLELKSHHKSLGLITADCD
                     DVTYTALDEATKASEVDVVYAKSMYAGAANASTKLAGEVLGIIAGPSPAEVRSGLNAV
                     VDFLEYGATFISANDDDSIAYYAHCVSRTGTYLSEVAGIREGEALAYLVAPPLEAMYA
                     LDAAMKAADVKMCELFAPPTETNFGGALLTGSQSACKAACDAFAEAVKSVADNPTGF"
     gene            23958..24659
                     /locus_tag="OE968_000511"
     CDS             23958..24659
                     /locus_tag="OE968_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMC domain-containing protein"
                     /protein_id="HCP7217828.1"
                     /translation="MDAIGLIEVIGYVAAIEASDACLKSANVNIVRVDKVGAGIVTLT
                     ICGDVGAVKAALEAGEIAASRVGTLRTSHIIPRIHNEVTNALFKTKEPKVCEVSEDKE
                     KNFEITLEIADNVSKNLSEKENVILDVNENSGDTENLYSDIDKTNKKIETVDDSLTEA
                     NEEKIENTNDKEVLEQVKIENSDFDRDDLSKNSVKKLKAMAKKLDSSITYKDLNVLKK
                     EELINLVKKLSRRDR"
     gene            24662..26131
                     /locus_tag="OE968_000512"
     CDS             24662..26131
                     /locus_tag="OE968_000512"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetaldehyde dehydrogenase (acetylating)"
                     /protein_id="HCP7217829.1"
                     /translation="MTLLDKDLVSIQEVRTLVRRSKVAQEKLSKMSQEQIDKIVKAVV
                     DAAFNNATKLAKMANEETGFGKWEDKVIKNTFASMGVYETLKNTKTIGIIGEDKEANT
                     IDIATPVGVVAGLIPSTNPTSTVIYKTIISLKAGNTIVFSPHPNAKNCILETVNIISE
                     AAIKAGAPEDSILCITNPSIVGTNELMKHKDTNLILATGGEAMVRAAYSSGTPAIGVG
                     PGNGPAFIDKSANVKLAIKRIIDSKTFDNGVICASEQSIVIEKSMEETVLKELKNQGA
                     YVLNEEESERLAKFILRANGTMNPQIVGKSVEVIANLADLTNVPKNTKVLVARENKVG
                     HNVAYSREKLTPILAFYVEENVEAIMNRCREILLNEGAGHTFSMHVNDEELVKRFALN
                     MPVSRILVNTPSALGGIGASTNLVPALTLGCGAIGGSSTSNNIGPLDLINVKRVAYGI
                     KEIEELGRDKSQVEKSMFDSMDKEELINLLVQKLVKELA"
     gene            26227..26514
                     /locus_tag="OE968_000513"
     CDS             26227..26514
                     /locus_tag="OE968_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMC domain-containing protein"
                     /protein_id="HCP7217830.1"
                     /translation="MASANALGMIETKGLVGAIEAADAMVKAANVQLVGKEQVGGGLV
                     TVMVRGDVGAVKAATDAGATAAERVGELISVHVIPRPHFEVDAILPKVSAE"
     gene            26641..27402
                     /locus_tag="OE968_000514"
     CDS             26641..27402
                     /locus_tag="OE968_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin adenosyltransferase"
                     /protein_id="HCP7217831.1"
                     /translation="MGVLTENEVKRKIGKNKNNITEFYIEKGQIITPSAKSYLAERSI
                     ELKYVDKLSDVNNEPKEVVKEVVKEKKYKYTTVFGAKLDEKPEHMTQLNGNLLVFKDH
                     KRIILRGKIDSLESEILKVQILCQKLDMPKLVKELQEVLDFVRNIMRCEVLDEKLGDF
                     KLLGLTPQELREQSHYPKKYFGIGHEFPSYEMGEVVVAINSIRSNTREVELAAYEAFK
                     GEYGNVHREDLIKALNRLSSVFWIMIYKVRTNKYK"
     gene            27415..28044
                     /locus_tag="OE968_000515"
     CDS             27415..28044
                     /locus_tag="OE968_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate propanoyltransferase"
                     /protein_id="HCP7217832.1"
                     /translation="MENLLNEIVEEVITRVKKEAFIEVEASGRHVHLSREDVDKLFGE
                     GYTLTKLKDLSQPGQYACKERVTITGPKGSIKNVVVLGPCRNETQVEISLTDGSTLGL
                     KAPIKQSGDLEGTLSIKISTQYGEVELDKGLMVAKRHIHMTPKDAEKFNVCDKEIVEA
                     KVMGQRPLTFDDVVIRVSDSFKTYMHIDYDEANACGYSKGTVAKIIKKA"
     gene            28086..28811
                     /locus_tag="OE968_000516"
     CDS             28086..28811
                     /locus_tag="OE968_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02536 family ethanolamine utilization
                     protein"
                     /protein_id="HCP7217833.1"
                     /translation="MNYDNLVDLITEEIYKKINSNEIKISNKPKAVIVFEQDNNKFNL
                     LKDGFEIVEFDKSIRECEIVIVSRLCMRGLSNIALGNSTSDEERFILKMIMNGKKVYV
                     LDEGIEYKKYKDTAPKALYKKFMSFEDEICKFGVEIIKDLNVITKNKLNIKKELESTR
                     GSKKEDTKVLDKDILNLTSVESVKIDNEFSLDLRNKKLISEADLRKPTINGVKNILVN
                     KKSIITPLAVDFMRIHHLKLKKL"
     gene            28824..29096
                     /locus_tag="OE968_000517"
     CDS             28824..29096
                     /locus_tag="OE968_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EutN/CcmL family microcompartment protein"
                     /protein_id="HCP7217834.1"
                     /translation="MDIGKVVGNVWATRKDEKLCGQKLLVVKILKTKDTYKEGFMVAA
                     DNAGAGNGDLVLISKGSSARESIEKSHVPVDATIVGVVDSFEVFDE"
     gene            29089..29640
                     /locus_tag="OE968_000518"
     CDS             29089..29640
                     /locus_tag="OE968_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMC domain-containing protein"
                     /protein_id="HCP7217835.1"
                     /translation="MNKSIGAIEFKSIAKGIEVSNEMIKKSSVDVLYLKSICPGKFLI
                     IVGGETSYINECVDYGIKLGEGYIVDNFVINAISQEILDGFKNKYQKLDSIVSIGVVE
                     SSKICAGIKMLDKTLKSGDLVLVKLQLSFAIGGKLVYIVAGDLSSLEYALKESENVVR
                     EKEVIYKTVIPSVDSQIIKSLIK"
     gene            29652..30743
                     /gene="eutH"
                     /locus_tag="OE968_000519"
     CDS             29652..30743
                     /gene="eutH"
                     /locus_tag="OE968_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization protein EutH"
                     /protein_id="HCP7217836.1"
                     /translation="MSINEIIIYVMVVFMVLGAIDKCIGNKFGLGEQFEEGIMAMGSL
                     AVAMVGVICLAPVLADVLRPIVVPVFNILGADPAMFAGSLLANDMGGAPLALELAKDP
                     NAGLFGGLIVGAMMGPTIVFIIPVALGIIEKEDQKFLATGILAGIITIPIGAFVGGLV
                     AGFEVMMVLRNLVPIIIFAVVIALGLLKFENAMIKGFTYFGKGVVIVITLGLAAAIVE
                     ALTGIVVIPGMKPISEGIEIVGDIAIVLAGAFPLVFVITKVFNKPLMALGKVLGMNDV
                     SAAGLVASLANCIPMFGMMKDMDNRGKIINVAFSVSAAFVFGDHLGFTAGFNSNMITP
                     MIVAKLVGGITAVLLAMVIANKTLKKENV"
     gene            30745..31218
                     /locus_tag="OE968_000520"
     CDS             30745..31218
                     /locus_tag="OE968_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF861 domain-containing protein"
                     /protein_id="HCP7217837.1"
                     /translation="MDISNIDKNLIETLVRQIIEEKISGTKDTVDFVRNKDISGITSI
                     KLPTVKVSESDRLDTGNPSDVVYTKDLFTLEESPRLGCGMMEMKETTFDWTLNYDEID
                     YVIDGTLDIIIDGRKVSASSGELIFIPKGSKIQFSVPDYARFIYVTYPADWASQN"
     gene            31731..32252
                     /locus_tag="OE968_000521"
     CDS             31731..32252
                     /locus_tag="OE968_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HCP7217838.1"
                     /translation="MEEIVKKEQASMNDIFLYLKAKSNSLYKFVILYNEFINKPKDYG
                     TGELINMVEVHMLTAIEENPGISPTQLAKIWNRTKGAISQTISKLEKKGYITKEKKEG
                     NAKTILLYPTTSGVELSKAHKLYDTIDVTRTFEYLIKECTLEEIDSFYKVIDLFINLL
                     EESPQENNDSEKV"
     gene            32631..33806
                     /locus_tag="OE968_000522"
     CDS             32631..33806
                     /locus_tag="OE968_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HCP7217839.1"
                     /translation="MNLKQLSEKYEEYVIQMRREFHKYPELSFKEIRTTQRIREELQK
                     IGVPFVSIEPNIVIATIQGKNEGKTIAIRGDIDALPMQEDSDVEYKSEYDGIMHSCGH
                     DAHGAMLLGLAHMLNDIRKDLKGRVLLVFQAAEEVGGGHKEIIQYFKENGGPDRLIAT
                     HVWSDIEAGKISVEPGPRMAGGSGWRIDITGRGGHGSRPDQSIDPIKPACDIVLKVSS
                     IPVNHISVLEQCVVHACAIHGGTTIGNVIPNNAEVIGGYRYFTEESGKKVFDIIKQMS
                     NGVGQVYGVDVKVTHTGGIGPVINDEEAVKMAKEIVSNIDGLELDSYEPICASDCYGE
                     ILKEYSGFYCYLGVGNKEKGIIYAQHHPKYNIDEDILKLGCEFMAKYAVEFLNKNNN"
     gene            33840..35378
                     /locus_tag="OE968_000523"
     CDS             33840..35378
                     /locus_tag="OE968_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbgT family transporter"
                     /protein_id="HCP7217840.1"
                     /translation="MQGALKENKKKSGGGFLGWIEKVGNKMPHPLALFTYITLIVVAL
                     SAIASFLGFSATSPATGKLIKVMNLISAKGLVLFMQEFVKNFQNFPVLGVVLVMAVAT
                     GVCEKTGFFSTAIKMSLSKVKGNAVVFIIAFIGVFANQAGDAAFVLVPTLAGAIFYGL
                     NRNPLAGIFCGFASVGGGFATAVIPGGWDVTLTPITVSAAQTIQPAFDMTLLASYYAL
                     FVSAFIVATVSTIVTVKFIEPKLGKYTGKPEGIDDNQGFEVTKEQAKAAKLAGFTVLA
                     YVALLIALCIPANSFLRSPEGSLIFGAPLMSCLQFFIVILFFLPGIVYGMRVGKIKTV
                     KDLNDILCQSMAAMAPFIVLAIVIGQFLTLFSVSNLAQVLAIKGGALLNSLPLPPQAI
                     ILLFLVLVAFINIFVISGSTKWMIFGPVFVPMLMQLNIHPAFTQFVYRLGDSVTNHLS
                     PLNAFFIILLATVQKYDKNAGMGTIFSAMIPYTIGYFVVLAVLVVVWMTIGIPVGIGG
                     QVWL"
     gene            35410..36612
                     /locus_tag="OE968_000524"
     CDS             35410..36612
                     /locus_tag="OE968_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HCP7217841.1"
                     /translation="METTEIRYNFDEVIDRSGTNCLKYDLKSQFMPESPEDALPLWVA
                     DMDFACAPEIINAMHERIDRKIFGYSSQQTDDYYEAVCGWFKRRFDWKIEKENIFFSP
                     GVVPALGFFTQILTQKGDGIIIEKPVYYPFEDKITNNERKVVNSPLKFEDGHYSMDYD
                     GFEELAKDENNKVFILCSPHNPVGRVWKKEELRKIVDICKKYDLWIISDEIHCDIIRK
                     GEKHIPLEVACPDYKDRIITCTAPSKSFNLAGMQLSNIVINNKELQEKWMLETDSKLA
                     IFLPNPFAIVATKVAYNDCEDWMNQVNEYIDGNIKYVEDFVNEYMPKVKIIKSQGTYL
                     VWLDFRGYGLDAKQLEYVMLNKAKVLLDEGYIFGEEGAGFERINVASPRTIIEECMNR
                     IKCAFEGL"
     gene            complement(36779..37378)
                     /locus_tag="OE968_000525"
     CDS             complement(36779..37378)
                     /locus_tag="OE968_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCP7217842.1"
                     /translation="MNDNIVEVKNINMNFYTKEGELEVLKDVNFNLKEGEILTLLGPS
                     GSGKSTILNILTNLLKPTSGDIKITGNIGYMFQKDNLLEWRNIMDNITIGLEIQGKKD
                     KKSLDRVESLLKTYGLWDFRSMYPKELSGGMRQRVALIRTLSVNPDILLLDEPFSALD
                     YQTRLLVCDDVYSIIKNENKSTILVTHDIGEARCIKVQL"
     gene            37548..38906
                     /locus_tag="OE968_000526"
     CDS             37548..38906
                     /locus_tag="OE968_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7217843.1"
                     /translation="MSNIITNLIESIFTNPITILFLLAITVYSVFKIIENNRVYSFVS
                     SKLDEINRDYKTSEFYKKVRDDYYTYSKENPYADVNITSFIEEVVSDLKHNNLPLLEK
                     IRSIKNSSSISILLGVLGTFVGLSTMLLCVDTKDIINSLPSTISSMQTAFTTSIFGVV
                     FSLIIGYFTKIKDCEHVLIQIMLKSENLLTSEITHFKSERMDLKVEEVKNTIKQISKS
                     IEAIEKFDKISKDLNDFNDEFISGIEALKSLLEGSQSSIKTFDQSVRKLDKQFNILNI
                     KFVKLFDKYDNQDNINKEILFDIKESSKNIYNATESQFKIRDYIKNINAGFALYERSA
                     QDLLTKLMTHENKISQNQKILLDEKFTLDDSIKNLSSIIENFSNDLQVKLDMMFENSL
                     DIQDKLDVMFNNSFMNDEVPLDSEELFKDDVNNVFNPFSEEIYEIEDKEIKVIGEDEL
                     NE"
     gene            38899..39531
                     /locus_tag="OE968_000527"
     CDS             38899..39531
                     /locus_tag="OE968_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HCP7217844.1"
                     /translation="MNNKYRRTVNREFEKSSFWPTFTDLLSTVLMVVILILFSSESIS
                     GSVEQDLAKNVNASVEETFKKSGIPVKVDKSNGQVTFGEKTMFDVDSDVLKPEAKEML
                     KMFVPKYIETIYKDYGDYISKIVIEGHTDDVGSYIYNLDLSQRRAYSVAKFIVGDEIG
                     DYKYKDKVTKHIIAIGRSKAELIKNGDNSVNRDASRRVELKYEININQNK"
     gene            39860..41017
                     /locus_tag="OE968_000528"
     CDS             39860..41017
                     /locus_tag="OE968_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HCP7217845.1"
                     /translation="MIEISIKNKKNSKIKTLILLLIVSISIYLTGCTTLDNGNNQSNN
                     NDSLSSSISSDKNVKIHFIDTGNSDAILIQDGKTFILIDGGDNDDEGLMVDYLNNQGV
                     KDIKYLIATHSHADHLGGLDSVVKNFNIENVFVSNGSAETKSYRDFINALANKGLSPS
                     VPLENNKFYLEDSYFEVLNTNGGDTTNEQSLVLVYTNGNDKVLFTGDAEEGTEKEILP
                     KLEKVDLLKVAHHGSRSSSSQEFLDKVNPEYAVLLVGKGNSYGHPHQETMNKLKKMGV
                     KVHRSDECSDIIFESTGDGVFTSCKDGSYNKGVREDGNSGKSNSNTSKNDSFKNKQNT
                     SNSEEIVYFTPKGKSYHSTKNCSGLSRSKKILSGTIAESKKNDPCDICYGK"
     gene            complement(41164..41799)
                     /gene="lexA"
                     /locus_tag="OE968_000529"
     CDS             complement(41164..41799)
                     /gene="lexA"
                     /locus_tag="OE968_000529"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HCP7217846.1"
                     /translation="MYLDLTEKQVLILEFIKSQIILKGYPPAVREICTAVGLRSTSTV
                     HSHLNKLEKLGYIRKDPTKPRAIEVLERSKVNDVSGANQEIIELPLVGQITAGEPILA
                     QQNIEEYIPFPASLVKGSNNFVLRVKGESMINAGILDEDYVVVDKKNTALNSQIVVAL
                     INGESATVKRFFKEGNLIRLQPENDFMEPIMLNDSEVEIVGIVTGVFRVIK"
     gene            complement(41903..43030)
                     /locus_tag="OE968_000530"
     CDS             complement(41903..43030)
                     /locus_tag="OE968_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HCP7217847.1"
                     /translation="MNNDKKIIKVHNKSDKPDNIVIKENELIEKCLLLENKLPVFMKD
                     YFIYLKGSVAVSTRLAYLEDINFFCSYLIETKELTNADCVKDITEDDFNTIKSRDINL
                     FLGDYCSRYYKNTEKNTLIFENNNRALARKKSSISTLFKFLYRNSQIDNNITDGFNPI
                     KLPKPQPDAIKRLEIDEVAKMLESVETGEGLTEKEKVYWRKTKLRDKAILALFVTYGL
                     RLNELRELNISSFNFSRGEFKIYRKRGKEVLMPINHTCEHVIKDYLQNERTRDELLND
                     EEKDALFLSLQNKRITAKAIRTLVKKYTSIPLDTTRDNGYSPHKLRATAATSLIQTGF
                     SIYDVQNLLDHDNVTTTQLYAAHKKNVKRDIVKNFEWIEDD"
     gene            complement(43351..44196)
                     /locus_tag="OE968_000531"
     CDS             complement(43351..44196)
                     /locus_tag="OE968_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7217848.1"
                     /translation="MIYIIEILKISVINIFCFIGIFIVFGLIFSITENLNNKFIFSSF
                     GKTGIIVTGAIGTFVHELSHLIMCLIFMHKINSVKFFRPIESKNDGILGYVSHSYKKD
                     NLYQSIGNFFIGIAPIIGGTIMIILIFKILLPDSYMKVTQNIDLKLYVSMINNLNING
                     FIHIILGDISNFIRIMLLTPSVYSLKYFIFMFLMYSISTHMSLSSADLKNSLNGLSFI
                     VIVIFVISSITYLFGFDNLNISSLIVKYNIFISFFMAIGFIFSIVTLIISYILSLVSP
                     FKNFS"
     gene            complement(44226..44597)
                     /locus_tag="OE968_000532"
     CDS             complement(44226..44597)
                     /locus_tag="OE968_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HCP7217849.1"
                     /translation="MKLKLLVEEYAVCRLNNDSKIPTWIDTEKFYSITRTDDELSVVC
                     LNNNIPSDVKSEKEWRILKILGPLDFSLVGILSKLSSLLADNKISIFAISTYDTDYIL
                     VKEKDIENACKILSCNGYEVE"
     gene            complement(44750..45010)
                     /locus_tag="OE968_000533"
     CDS             complement(44750..45010)
                     /locus_tag="OE968_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003866776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein S"
                     /protein_id="HCP7217850.1"
                     /translation="MEVLKVSSKSNPNSVAGALAGVLRERGVAEIQAIGAGALNQAIK
                     SIAIARGFVAPSGMDLVCIPAFTDIEIEGDKKTAIKLIIEPR"
     gene            complement(45199..46143)
                     /locus_tag="OE968_000534"
     CDS             complement(45199..46143)
                     /locus_tag="OE968_000534"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit alpha"
                     /protein_id="HCP7217851.1"
                     /translation="MIENNSEKIKVLENDIKQLITISKANNIDLSDKINSLNEKLEKL
                     KEDAFSHLSAYEKVTLSRDIKRPTTLEYIEHICSNFLELHGDRLFKDDPSMVGGIGQI
                     GKFNVTIVGHQKGRDTKENIKRNFGMPHPEGYRKALRLMKQAEKFNRPIITFIDTSGA
                     FCGLEAEERGQGEAIARNLLEMSKLSVPVITFVIGEGGSGGALGIGVGNDVCMLEHSV
                     YSVISPEGLSSILFKDSSKAKEACDVMKLTSNDLYDLKIIDKIIKEPLGGAQKDVEAV
                     SKEIKAYILERLNHYKDMDKEEIIAQRYKKFRNIGKCL"
     gene            complement(46164..47018)
                     /locus_tag="OE968_000535"
     CDS             complement(46164..47018)
                     /locus_tag="OE968_000535"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HCP7217852.1"
                     /translation="MIKKFLSSKESKYVTISLDDNFKKNSVDDKFWTYCKGCDSHVFR
                     KDIEENSFVCPKCSRHYGLRARKRINLLIDKGTFMEFNSDVEFQNPLNFPKYKEKVDS
                     YKEKTKESEAVVTGYGRINGIKTVICVMNPDFMMGSMGSIVGEKITYSIEYAAENNLP
                     IIICSASGGARMQEGMVSLMQMAKTSQALSKLEEKLLPYISVLTDPTTGGVTASFAML
                     GDIIISEPNTLIGFAGPRVIEQTINQKLPEGFQTSEFLLEKGFIDMIVDRRKMKEVLY
                     QILAMHKK"
     gene            complement(47033..48394)
                     /gene="accC"
                     /locus_tag="OE968_000536"
     CDS             complement(47033..48394)
                     /gene="accC"
                     /locus_tag="OE968_000536"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HCP7217853.1"
                     /translation="MIKKILVANRGDIAVRIIRTCKELGIKTVAIYSEIDKDCFHRYI
                     ADESICIGPNNISKSYNNIENIIYLALKLKCDAIHPGFGFLSENPEFAKQCEDNNIIF
                     IGPTREQMILMGDKSRARETMMELNIPVVPGSESVLKTKEEALEVAREIGYPVMIKAS
                     SGGGGKGMRIVRKEEELFSNFDMASSEALAAFSNSDLYMEKFIENPRHIEVQVFGDKH
                     SNAIHLGDRDCSMQRRNQKVIEESLSPYLSDEERQKLHKIAVDIVKGVGYIGAGTIEF
                     IVDKDKNFYFIEMNTRIQVEHPVTEMVTNLDLIKLQISIANGDKIPFKQEDITFRGHA
                     IECRINAEDSSKNFAPSPGKIESLNLPGGFGVRFDTFVYAGYTIPPLYDSMIGKLICW
                     AETREECISRIYRALDEIIVEGINTNVEFQKALVTSEEFREDTHHTKFIEDVFMKKEF
                     ATL"
     gene            complement(48410..48862)
                     /gene="accB"
                     /locus_tag="OE968_000537"
     CDS             complement(48410..48862)
                     /gene="accB"
                     /locus_tag="OE968_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HCP7217854.1"
                     /translation="MNINEIKELLKAIDSTNLEYVKLESSDLRLEVSKKAQSTSSPVL
                     SVQQESVVDLSLEKPVVNDTPVTSNENLSVVVAPLMGTFYDSPSPDADSFVKVGDVVE
                     EGDTLCILEAMKLMNEITSEIKGEIIEVLVSNEELVEYNQPLFKIKPL"
     gene            complement(49132..49578)
                     /locus_tag="OE968_000538"
     CDS             complement(49132..49578)
                     /locus_tag="OE968_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7217855.1"
                     /translation="MESKFFNWYTQSLGGTFGIISCICAYLNGYMFVYTNSASKYFES
                     IGFLGIISSYTLLPLCMLTLIFGVIYSYTPETSDKSIFNIPFFTLNKRLILITVVFGF
                     IGARVYFIIPAILITFNLYSNVLIAKLKYILCKNKENDTNLKESEV"
     gene            49853..50131
                     /locus_tag="OE968_000539"
     CDS             49853..50131
                     /locus_tag="OE968_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7217856.1"
                     /translation="MVDTLEFGLKILFFILSIIWMGKIMILRTDKQIVINPLLIGISA
                     VLVMLHTSQSNIEFFGLDVQYIRIVLYIIYSLIILIGIWATNRRNGIF"
     gene            complement(50260..51006)
                     /locus_tag="OE968_000540"
     CDS             complement(50260..51006)
                     /locus_tag="OE968_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7217857.1"
                     /translation="MWEGTMNLANLIPFIISAAALSPINSNDKVLSENQLKDIFPDAN
                     LRAVVKRYINPDEMTISNIKALDGEFYATGESISNLKGISYLENVDNFIFWNNNIKEI
                     PKEALSLKDMDSINLANNYLIDDDVVNSLSHNGVDVNCDLNFIDTKDNQYKLDSKYHN
                     VDIAKGESIDLRKIITKKIDSYYKYWEVTDNLPKDLNFIVSVSDKSVLSCEDMIIKGN
                     KTGQAVVKVILSDKNDLNTSQEVLITVNVK"
     gene            complement(51135..51779)
                     /gene="trmB"
                     /locus_tag="OE968_000541"
     CDS             complement(51135..51779)
                     /gene="trmB"
                     /locus_tag="OE968_000541"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HCP7217858.1"
                     /translation="MRRRRKKGADEKLLSYTKYVLRDDIDKLKGKWNLKFRNDNPIHV
                     EFGTGKGKFITTLAKQNPDINYIAMELKEEVLLKAVEKADASNLNNILFLWGDVSNIL
                     DYFEAKELSRIYINFCDPWPKNRWSKRRLTHSGFLEMYNRVLEDDGEIHFKTDNEKLF
                     EFSLNEIAANNWLLKNISLDLGNSEYENNVTTEYEDKFMSQGMRIFRCEAKKRN"
     gene            complement(51917..52237)
                     /locus_tag="OE968_000542"
     CDS             complement(51917..52237)
                     /locus_tag="OE968_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein HesB"
                     /protein_id="HCP7217859.1"
                     /translation="MKITLPETAIDTLKSILKDNQDKPNNIRVYFAGVGCGGPSFGLA
                     LDEKKEDDLTYEVGELQFVMSSDEYSQYGDIIIEDTGFGFRVIPENMKDQGGGGCSGC
                     SGCH"
     gene            complement(52690..52938)
                     /locus_tag="OE968_000543"
     CDS             complement(52690..52938)
                     /locus_tag="OE968_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HCP7217860.1"
                     /translation="MQKTKAWGIIEPEKPESQQQMAHMDFAVNDLEEAVQYAIHCGAT
                     IAEEQFTDDWRVMIDPAGHPFCLCQMKSIMESSHFSLL"
     gene            complement(52969..53430)
                     /locus_tag="OE968_000544"
     CDS             complement(52969..53430)
                     /locus_tag="OE968_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase/bleomycin resistance/dioxygenase
                     family protein"
                     /protein_id="HCP7217861.1"
                     /translation="MKFGGVLLIVKDINKSKKFYEDVMEQKITLDLGEHVSFENGFGL
                     QSNYKAIIGYDLPIYQQSNNFQLYFEVNDIKQWESKINRIGNIEFLHYIKEYPWGQRT
                     FRFYDFDKNIIEISESMESVIKRLLKQGLALEEISKRTMYPVEFITQFQQL"
     gene            complement(53468..54301)
                     /locus_tag="OE968_000545"
     CDS             complement(53468..54301)
                     /locus_tag="OE968_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCP7217862.1"
                     /translation="MLKKESIHFINKNRSLIVCEDNFVYLLPCIQLRNWISNFTISFP
                     NQTIISDNYTIIPHGSVTLVFFYDATGLHSLLFGPTTKPKTVGNIANRCDVILIIEFQ
                     PAGFFPLIGIQQSELIDKVVPFSIINTSLDLEIKKIFNESLSIDKLILKLEELLISNI
                     KIEYSYEFILAIQLIIQNSGNISSQEISKKVFYSSRHLNRLFNQYLGLSMKSFSRLVR
                     INKSIKLLNNNKTSLMSICNELGFYDIPHFIKDFKIVCGITPQKYRANMSDFYSEIAK
                     F"
     gene            complement(54575..55261)
                     /locus_tag="OE968_000546"
     CDS             complement(54575..55261)
                     /locus_tag="OE968_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCP7217863.1"
                     /translation="MKITHNSLAVEAKNIIKEYKIGNTTTRVLKEVSLQVMKGEFVSI
                     MGQSGSGKSTLLYILGGLDTPTSGKVYMNGADISHFNDEKMSIIRRRNIGFVFQFYNL
                     IPNLNVEENIMLPLLLDGKNLKDYKNQLDEILDIVGLTDRRKHTPRELSGGQQQRVAI
                     ARALIGKPEILFADEPTGNLDSKTGIEIIDLLNKINRDNGQTIIMVTHSPEAAKSSSR
                     TITVSDGLIV"
     gene            complement(55276..57753)
                     /locus_tag="OE968_000547"
     CDS             complement(55276..57753)
                     /locus_tag="OE968_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HCP7217864.1"
                     /translation="MKIILKYIFTNIKERKIRTAVMLLSIVLSTVLLFVSFSIGLSYE
                     SAQRKMAKGMYGTATISVQSKNPDILTNLEDIPDLNAIKSKVGVLESSAIYNKGGYYE
                     EFSLISADLSQLNKINKPRLENGDSITDFSGDKIILPNRFTSKYKIKKGDSITLQIYG
                     KSYTFQVSDIASYDTVFLRNTRGVNALLPKETLSKIINKGSGYTRVLIESEEEITENL
                     VNKLSKELSTEKYMVSNTINETKIISDARQKTMPFFLISFFALTLSIFIIYSSYKVIT
                     LERLPFIGTFRSIGANEKTVTRILMLESILYGSIGGLIAIPIGVVVLNLMLHGLGNSL
                     EQGISIPVVISPIGVIISVIVAIIVSSFSAYIPVKKASHLPIKNIVLGTVEEKNVSNR
                     SILFIGSIMFILSILLPRISPENTLYLAGGFSLLGLIVATIVLIPLITDIMSIVFEFV
                     YKNILGNEGKLAARNMKNNKNIIQNITLLFISISAVIAISVVGNFVKTYITDVFRDAE
                     LQGFADGKMNEEFIEDVRHMDGIKKILPLYVMNNEISGNGVTLSRLEGTDNIKLYNSM
                     FGINYTNFEIKKQVIEAFNDKRSVILNEDTLKKVGLSIGDTITLSNDKYDFSYKIVGS
                     FKSRANDVEAVIPSHYAVNDFDKTNYGFLVYTAVNPDAVMIQIRYLFGDTYNWSRTVE
                     EFNNDSLNTISSFLSPMNKMTYFIFLLATVGIINNLLINYIQKRRSIAMYKSIGLSNK
                     QNIKVTLIEGFTSGLLGAVIGIVISILEIQTIFIVAGPKISMKPDLDFKTFIIVGLLG
                     IIVTLIGSIVPIIKGKKMKLIEEIKFE"
     gene            complement(57972..59375)
                     /locus_tag="OE968_000548"
     CDS             complement(57972..59375)
                     /locus_tag="OE968_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HCP7217865.1"
                     /translation="MHKPSYKTVFHSYIIFFMIFICLILTVIGIFLSLITIQKPNGEF
                     IRSDWPKKFTENFNEQIVFIDNKPQVKQSGLEKLRENQLWLQILDSSGNRVYGFLEPK
                     EHKDYYSNSELLALANQNNSSNGTVYFNTIKNNKNDYIYIIYFPLNISKVNMFFDGGK
                     FIGGKSIVFSIIGIIFLIILVSGIAYGYWVTKCISNITSAVSDISKRSYLPVNIKGVF
                     ADIYNSLNILNEEIHRSDEIQNKTDIMREEWISNITHDLKTPLSPIKGYAELLTDSST
                     NYSPEKVYKYASIMLKNIEYTNTLINDLKLTYQLKNGIIPLNKNNYDLVRFLKELSID
                     ILNYPEYESNIVEFKSNIDNINFDFDCTLLKRAFSNLIVNAFTYGDKNTKVCVHITLN
                     ERIEIIISDNGKGMSREEASNLFNRYYRGSNTKQKIEGTGLGLAITKQIIEVHGGNIS
                     VESIPGLGSSFYITFPI"
     gene            59868..>60710
                     /locus_tag="OE968_000549"
     CDS             59868..>60710
                     /locus_tag="OE968_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HCP7217866.1"
                     /translation="MKKQKSPILLEMLGLFFGCISMSIGINMFLKPHTIAPGGLSGLS
                     LVLNKVTGLPVSAIMLIIGVPLVILAFRIMGTKNSLKTLFGTVVFSAIVQLTDPLSKL
                     RFTNDLLLSSIAGGILVGIGLGIMFKSDASTGGTDLIALILSKKFPGIKATKFMSCLD
                     GMVVISSGIVNRSLETALYSGIALCVLIKIADMIMEGFDHSKAFFIISDEPESLRQAI
                     TEELDRGLTILDGKGGYTRENKEVLLVVVSKKQELYLKRLVKRTDPTAFVIVTDVHEV
                     LGEGF"
BASE COUNT        22365 a         8475 c         9626 g        20244 t
ORIGIN      
        1 atcagcggtt atctaacaaa gaaattgcag gacttgaatg ttgatactat tagaaccgat
       61 atactgacta gccccacagt tacagatgta attgtgtgga atatcgaaca gtcgggaacg
      121 gacacttttt ctgctaccta cgaagtagat cagcagataa aagagggaga acagacaaca
      181 acagtcaagg caacctatac ggtaaaagtc catgtagacg ctgacaggga tatggtaatt
      241 attcagaacc ctacccttgc accagcaatc gaaaaatcgg actatgagcc aaagacacca
      301 gaagcagacg caagtgtaga cgctgatacc gtgaatgacg ctaccgcatt tctggaaaca
      361 ttctttaagc tgtacccgac agccacagca aaagagcttg cctattatgt atttggaaat
      421 gtgcttgaac ctatcggcag ggactacctt tattcagaat tggtaaaccc agtacttaca
      481 aaggacgggg ataatatgaa agtcaaggta gctgtaaaat tccttgataa tcagacaaag
      541 gcgacgcagg tattgcagta tgagcttatt ctacataagg atagtaactg gaaaattatt
      601 atgtaagaca ttttgttggc aggatctatt ttcggatata gtctgccttt tctgtagcaa
      661 atgtactgca ctgacaagct atttcattgt attttaagca attaaacctt tcttgacaat
      721 tttatcttaa atcatatatt tatggatatt gactttctgc ttgcaataag ctataatatg
      781 actataaaat caaatcagtc atataggagg tatgtggtat gtataaagaa gttggtattt
      841 cttcaaataa tgttccgata acactttcta tctggtatac agaaagaagt agtcctacca
      901 ttgttttttt gccgggtact atgtcacacc ctctcatgta tgagaatttt ctatgtggtt
      961 tgagtgaaag aggatttaat ataataggca ttcactatct ttcacacgga aaaagcccta
     1021 aaatcaaaaa aaattataca atggaagatt tgctgcataa tgtatatgac gcaacaactt
     1081 acggaataga aaatttcggt gaaaacatag ctgtcatggg ttccagtcaa ggcgggattt
     1141 tagctgcaat ggcggcaggt agggacacaa ggttaaaagc cgtttttcca cataatatca
     1201 tgctgaccac attaaaagaa actatgagct taacaaaata tcccacatgg tcgcaccgtt
     1261 ttatggggct gatacagtgg ggctttcgtg taggtggaaa attgctgcct aactacaagg
     1321 ttccaggaga cgcttattta gactatgaca gagtatttta tagtgaacag gcaaaacaag
     1381 attgcttaaa tgaccctatg cttttaccct attatccttt aagatttgtc accagcttat
     1441 ttaatgctga cttatcgtgc ctggagaatg gggctataca atgtcctgtt attttaatta
     1501 ctgccaaagg cgacccgctt tttagctttg attataccaa caaagtattt gatttaattc
     1561 atgtaccgca aaaggaatta cttgctttag agcttaatcg tcacatgatt tttaatgagg
     1621 acacggacac tacaataaac gcattggaag ctaccttgca taaatatctt ggatagcata
     1681 ttgattatat aatcagtaaa tgttatactt ttcatgacga tataaatatt ttagtcataa
     1741 ggaggttatg agtttgccac gatttacgga acaagaaaaa gaaatcataa acagtaaact
     1801 tttgatagag ggagaaaagc tgtttgcatt acacggctta aaaaaagtaa cagttgatga
     1861 tttagtagct gctgtaaaca tatcaaaagg ttctttctat gctttttatc ccagtaaaga
     1921 acatctatat gttgaaatca attttcgctt acaaaaagag ttatttacaa gtatagaaac
     1981 aaccattaaa aagaaaaagt ataagaacca tagagattta gcaaaggacg ttatcatgct
     2041 aagtttaacg ggggtgatta cttcgcctat tctttcacag attgatttat ctttaatgga
     2101 ctatctgcaa agaaaaatat cgtcagatat ttttgaaaat catatgtaca gtgatattcg
     2161 tatattggag atattggaag atttaggggt tgtatttttg gttccgcata cggttattat
     2221 aaaatccctg tattctgtct tatcctgttt ggaacaattc aaagaggacg aagaactgaa
     2281 tatgatacaa aatcttttag tgaatggtat tattcagcaa gtagtagcag agtaacaatt
     2341 ttgtttggtt atttgacagg caggtagcca aacaaatttt ttacagttta tatgactata
     2401 tatctataaa cgtcataaag ttaaaggagg aatgaataat gattgatgta aaaaaactgt
     2461 attttagcta tactgacaaa ccgtttgtgg agaatgtaag tttccatgtt gggagaggag
     2521 aaatttttgg ttttttagga ccctctggtg ctggaaaatc aactattcaa aaagttttaa
     2581 ctgggcttaa tacaagatat aaaggcagtg taaaagttgc aggtacagaa ataagggagc
     2641 atacaaatca gttttatgaa aatattgggg tagactttga attttcaacc tgctacgaga
     2701 aattcacagc acgacaaaat ctcgcctatt ttgcttctct atatgaaaag caacctcggt
     2761 ctattgatga attattgcat atggtaggct tggaaaatga cggggacaaa aaagttgctg
     2821 acttttccaa aggtatgcgt tctcgcttga atttcattaa agcgttagtc catgaccctg
     2881 atatattatt ccttgatgaa cctacaagcg gtcttgaccc tacaaatagt cgtttaatga
     2941 aagatattat tcttgcggaa aagaaacgcg gaaaaacgat tatcattact actcacaata
     3001 tgtttgacgc aacagagcta tgtgaccaag tagcctttat cgttgccgga aaagtcagtg
     3061 cattggatag cccgcataat ttgattatgt caaggggagc tgccaaaata caatatacct
     3121 actatgataa aggcgagaaa accggagaat gtctgcttga tagaaccaca gaagataagt
     3181 tgttaaaaag tttaatttcc gaaaaccgtt tgctttctat tcatagtagt gagcctacat
     3241 taaatgatat ttttgttgat attacaggga ggacacttca atgagattgg gacgtttaat
     3301 ttgtggtgat atacatttcc aatggaaata tggtttctat tttatctact ttatattaac
     3361 agttttatat gtgtgcggga ttgccgcttt gccggaacat tggaaaacgg atattgcttc
     3421 tattatgatc tactctgacc cggcagcaat gggattattt tttatgggag cgattgtcct
     3481 cttagaaaaa agtcaaaagg tgttaaatgc tatggtggta tcccctgtaa aaatatcgga
     3541 atatatactt tcaaaaacag ttgcgttgat tgctatttct acggtaatcg cattgatatt
     3601 aggggtagtt tccggcagca atcatttact gggtatcgca gttggtacgg ctttgacctc
     3661 agcaatcttt actatgcttg gaattattgc agctacaaaa atttcaaact tgaaccaatt
     3721 tctcattgtg attatgccga tagaaattat ttgctttgta ccacctattg ttggtctgtt
     3781 tgtgaagtta ccatatctgt tccgcttttt tccattcaca gcttgcatga accttataac
     3841 tggaaaaagt gttttactat cgtttgatat ggtacttgta attgctacgt tgattatcct
     3901 ctacatagtt gctcgacata cagttgagca tatgtggaaa agtttgggag gtgtaaagct
     3961 atgaaaaaga tattatccag caccatacag atatttaagc aaatcaaaag tgaccctatg
     4021 atgtttgcgg cttgcttctc cccttttatt atggggactt taattaagtt tggtattcca
     4081 tttcttgaaa gaataacgaa gttttcttta caagcgtatt atccgatttt tgatttatta
     4141 ctttctatca tggctcctgt attgctctgc tttgcatttg caatgattac attggaggaa
     4201 atcgacgata aagtgtcacg gtacttttcg attacccctc ttggtaagtc ggggtatctc
     4261 tttacaaggt tgggagtacc ctcaattatt tcggcggtca tcgcttttat tgtactgtta
     4321 cttttttcat tagaaaagtt gtccattgga atgacaatat gtttggcgct tctcggctca
     4381 gtacaggcaa ttattgtttc acttatgatt atcacattat caagcaataa attagagggt
     4441 atggcagtta caaaactagc tgcacttaca ttgctcggaa taccagcccc cttttttatt
     4501 gatagttact accagttcgc ggttggcttc cttccatcat tttgggtagc gaaagccatg
     4561 cagaatgaag cggttcttta tttctccata ggattggtgg tagctttagt ctggtactac
     4621 ttccttacaa aacgtctgtt tcggaagctg gcaggataag gaggcatatt atggaaaaag
     4681 gtagacttct gcaaaacaaa aatatgaata aggctattca ggtttccaaa attacactaa
     4741 tcatcaatct gagtttatcg ctacttaaat ttgctgccgg atatatagga aagtcaagtg
     4801 ccatgctgtc ggacgctgta cattcggctt ctgatgtagt aagcacaatc gttgtgatgg
     4861 ttggaattaa aatatcagaa aaacagcctg atagagaaca tccttatggg catgaacgta
     4921 tggaatgtgt ggcttccatt attctctctg ttgcattggc tataacgggt gctggaatag
     4981 gatattcagg tatcaagaaa atcttttcag gacagtacaa tacgctttct gtccctagtg
     5041 gaatcgcact tacggcagca gtcttatcta ttgttataaa agagtggatg tactggttta
     5101 caagaagtgc tgcaaagcat acaaattctg acgcacttat ggctgacgca tggcaccacc
     5161 gctctgatgc actctcgtcg gttggttcct taattggcat tttaggagcg cgtttaggct
     5221 atgctattct cgatcctatt gcaagcgttg tgatttgcgg ttgtatctta aaagctgctt
     5281 tgaacatttt caaagaaagc attaacaaaa tggtagacca tagttgtgac aatgctactg
     5341 aaacaaggat tagggaagtt gtgcttcagc agcaaggggt tgatggtatt gatgaattaa
     5401 aaacccgcat gtttggagcg aaaatgtatg tagatattga aatattagct gatggtaatt
     5461 tagctcttta tgacgctcat agaattgctg agggagtcca tcaaacgatt gaaaacaact
     5521 ttccacaatg taagcattgt atggtacatg ttaatacgaa tgaacttctc tattctgcat
     5581 aggacaggga agatgattta aggctattga aagggaaagg agggaagtag gttatggaac
     5641 aatactggtg gattatcatt gttgtggttt tgattgtcgt tggcttactt aaaattgtaa
     5701 ttatgaagaa gtataaccaa aggagaaatt ctaacaatcg ttcaaaagat agcgaggacg
     5761 acaagatgta ttaaggttta ttgaaatctg ttatgttgta gaatgatgtt tttagatact
     5821 agaaagtgct ttaagggggg ctaacgttaa ggaaagcttt gagtacaatt ctttacaatc
     5881 aacagtcttt tgcatagaga aatgtatgta ggaaatatgg tgcaaggcac aaaacaccag
     5941 caattgagaa atcaacctat gaaccaaagg cacactacat tttatactac ttgacaagta
     6001 aacgaacatt tactttaatg gtttaaagaa gtaaacgttc gtttactaaa gaaggaggtt
     6061 gtaaatgtct gacacaaaag aaaatatatt aaaaattgca ctacacttat ttgcagtgaa
     6121 tggttatgag gctgtttctg ttagtatgat tgcggaagcc ttgggaatga caaaaggagc
     6181 attatataaa cattataaaa ataagcaaga tatttttgac tgtatcgtag aacgtatgta
     6241 tcaaattgat aataagcgag ctaaggatta tcaagtacca gaaagcacaa tagaggtaac
     6301 cccaaatgca tacagaaata caactattgg aagtctaata acatttactc ttgcacaata
     6361 cgatttttgg gtgactgatg aatttgcgtc taattttcgc aaaatgttaa tactagagca
     6421 atatagaaat ttaaaaatga atatgcttta tcaaaaatgt cttgtaaatg gtcctatcag
     6481 ttatatagaa gatatattta atgaaatgat tgaaaaaggt gttcttcaag agtgtgatac
     6541 aaaacagctt gctattgaat attatgcgcc attatttcta ttgataagtg tagcagacgc
     6601 agttgaaaat tgttgggatt taaaaactca attaactaca cacgttaaac aatttgtcaa
     6661 gaaatatatt ataaatgaga aagtaaaata atcctttatt ctgtcctaaa tataaaccta
     6721 actttttaat ttcagcagag aaactcaaaa tgaatattgt tataagtcac aaatattaac
     6781 tattaaaata ttacaataac ggagatgaga aaatggaata tattcgcagt aaaaaatatt
     6841 ttacacccga cttacagaca aaaattatgg ggccgaatcc tataaaatta caagaggaac
     6901 tattacaaaa tcataaaatc ccgtctggta gctatgtctg tgaccttgga agtggacaag
     6961 gtttaacttc tgtatttctt gcaaaagaat atggatttgt tgtttttgca gttgacttat
     7021 ggagtgagcc aaaagaaaat gaagaatttt tcaaaaaaat gggattatct tctgcacaaa
     7081 ttaaatctgt aaaagctgac gccaatgaac ttaaatttga gaaagagttt tttgatgctg
     7141 tagtaagtac agattcatat aattattttg gacgtgaccc tatatattta gatgaaaaat
     7201 tgcttccatt tgttaagaaa ggtgggtttg tttatatcac agttcctggc atgaagaaag
     7261 attgccatga gaaacttcca gaagagttat tgttatcatg gacaccagaa gaacttgatt
     7321 atatacatga tataacatat tggtctaaca taattagtca ttgtaaaaag gcagatttaa
     7381 tttcaatata tgaaatggaa agtaattcgg aagtttggtc ggattggata aagcaaaata
     7441 atgaatatgc aataaatgac cgtaaggcaa tagaagctgg cggtggagat tatctgaatt
     7501 ttattgctat aattctacaa aaaaaataaa ttctttagaa ccaaacacta taatttgcgt
     7561 tctaatatgt ttaccgattg acatcaataa ttttatcttt gagggtaatg atttgaaaat
     7621 agaagaatac aagaagatac gaaattgata aattagaatt tgatgggatg gtgatattat
     7681 gaaaatatta tggatcatta ttattatggc agataatctg ctgccgttac tgcttgctcg
     7741 tttctatcca aactataagc ataaagaaat ggcactatct gtccttggct ctcgtcaaag
     7801 cccggtgaaa tggatatata atgtgtggtg cattatatca ggtgtggtat tttgtatcgc
     7861 tccatatgcg ttgtatcaag agaacgatag cggatgggca atcgctatat ggatgcttct
     7921 tgctatatac ggcatcgggt gtgaaatcat ttccggagtg tgcccgttaa atgaaaatag
     7981 acaagacgaa gatataatta caaaaattca cggcggcaca tcggcaatcg gatttatggc
     8041 cttgcttgtc gttcctttgc tctttgcaat tctgcaattc caaacaacaa aagtagtgtt
     8101 aggcgcaatt tcactggtgt gctttacaat agcattcata ttcttctgct tttttattat
     8161 gggtgagaag gaaaagtttg caaatactgt tttgagatat ggcggtcttt ggcaaaggct
     8221 tgttttaata agttgttata taccgttatt tgtttggtct gtttctaatc aataaaattt
     8281 agtttatagg aataacaaat tccagtttgt aaaagtcaat aaatccaaag ataaatttgt
     8341 atttgaaagg agttttgaag aatgaaaaaa tatgagtatg tagaaattaa ctataatgcg
     8401 aaaggagttg tattcctttg tactgataaa cacaaagaaa ttattgacag ttacgcaaaa
     8461 acggggtatc actacgcagg gtttgtaccc acagaaattg acgcaaaagg ctgtatgcga
     8521 aagatagatt taatttttga aaaagaagat taacttattt tagggagttg gttctaatga
     8581 taggacttaa aagacgagat atgaattata ttatgaaagt tggtgctaaa gctcaaggtg
     8641 tttctgtatc tgaatttagg gctatgctac aagataccat agacaaaact atggaaagta
     8701 cagacccaga cgtgcaggca aattttaaac gatactttgg aaataagcgc ccaacaccag
     8761 aggaatatat ttatacgatt accaaaaaga caaaggttaa ggtttaaatg ttgtaaaggg
     8821 ggcttgccgt atgaaacgct ttatgtacaa ttcagtatat tcaagcccaa tttaacagca
     8881 tactatttac aattaaatac gctataccag tagctcgtac aaaatttata ttttgtgcgg
     8941 gcttttttaa tacccgaaaa gtttttttaa ttattttcat ttttttggaa gcaaatcaca
     9001 ccttgctgta cagatatggt gcggaaagag ggataaacac ttttcaattc atagctggaa
     9061 aggaggtgag attatgaaac cgtctgactt ccaaaaaaca attcagtgtc agtttgaatg
     9121 taagctgaaa aaagttgtca aaggtattat ctggaactac cgtaaagaat taaaacgaag
     9181 aaaaaacaag gaaatatctt ttagcgaatt accagacatt acggtagaaa gtctggcaac
     9241 atgggacgac tacgaaacaa actacacaat ttttaatgtg tgtggcatag atattaaagt
     9301 ccttgatgat gaacttgcag aagctctcaa acagctaccc gaaaaaaaac gtaacaatgt
     9361 attgatgtat tacttcttgg aaatgagtga tacagagatt gcagatatta tgaattatac
     9421 cagaggggct gtgttcaaac acagacaccg tgcactagaa actatgaaag agatactaaa
     9481 ggagaagaaa tagaaatgaa gaaaaagtac aagcacccgt cttattattt gatttcatca
     9541 gctatggatg gggatgaaac tgcgattgag aaattactgg cattctatga cccgtacata
     9601 tcaaagtgtt gtttacgtcc tttatatgat gaatacggca atgtttatat tgttgttgat
     9661 atggaattaa agggacgtat tcgagaagcc ttaatcaaaa tgattttaga ctttgagatt
     9721 gatatagata tagaaaccga agaagaataa gcaaatacca gcagggcgtg attggttaaa
     9781 ttcccttctt tcctgccctg ctcctgcttt tatacatgga agcctacggc tttcgccgat
     9841 tgttctttga caactgaata aagcagacag atacgtttgt gatacagcga gccacgggga
     9901 ctgtacgcca tgacctttcc gacaagaaag cgagcgaccc acgcagttga tccgagagcg
     9961 acttgtggaa tggtcgtttt gccatgacct gctatcacag aataatgata cgtccgcatg
    10021 gtgcggttct gcccacaaga atgggaatag ttgagatact aacggagctt tccaaagccg
    10081 tctgtctgct tatgataaga cacacagaaa ggagttgttg caacatgaac aatactgatg
    10141 tgccgatttg ggaaaaatac acccttagta tagaagaagc gtcccgatat tttcgtatcg
    10201 gggaaaagaa gttgcgtaaa cttgccgagg aaaatctgga ctctggttgg gttatcgtta
    10261 atggaaaccg tattcagata aagcgaaaac agtttgaaaa aattattgat acactggacg
    10321 aaatctgatg tcttagagcc gtagatatgg tataatatta gtagcgtatc acggctcatt
    10381 ccatgacgga aaggagcttt acactatgtc aaaaatgaaa agacaagaca gtaaaggacg
    10441 caatttgcgt cttggagaga gccagagaaa agacggaaga tacgtttata aatataccga
    10501 tatattcggg aagccacagt ttgtatatgc ttggaaactt gtaccgacag acaaaacacc
    10561 tactggaaaa cgtgatgata aatcattgag ggaaaaagaa aagcagataa aaaaagacct
    10621 tgacgacggt atcgacacta tcggcggtaa aatgacagtc tgccagcttt atgcaaagaa
    10681 gaacaaccag aaaaagaaca tcaagagaaa cacggaaata ggacgacagt atcttatgaa
    10741 cgcactagaa aatgacccat taggtatgag ggcgattgat acagtcaaac agtccgacgc
    10801 taaagaatgg gctatcagaa tgaatgacaa aggttattcc tataagacaa tagataacta
    10861 taagcgttcc ttaaaggctt cattctatat ggcgatacaa gacgactgta tcagaaaaaa
    10921 tccttttcat ttcaagctaa gtgatgttct ggaagatgat acagagccta aagttatctt
    10981 gacaccagag caggaagaaa aacttctttc ctttatggaa acggataatg tttacagcaa
    11041 gtatcgtgat gaagttattc ttctgctgga aacgggactt cgtatctctg aattatgcgg
    11101 actgacaaca cacattgata tgcttaatcg tgtgattaac atagaccacc agctattacg
    11161 tgatacagag gtgggctact atatttccac acctaagaca aaaaacggca agcgagagct
    11221 tccattgaca gaaagagcat atcaggcact tgaacgaatt ttaaagaacc gaggaaaagc
    11281 tcaaccgctt gttgtagacg gttatagcaa tttcttgttc ttgaaccgtg agggcttgcc
    11341 aaaggtagca ggaaattatg aaagtatggt gcgtgggctg attaagaagt acaacaagac
    11401 ccatgaggac aagttgccga acatcacgcc ccactcattc agacatacct actgtacgaa
    11461 catggcaaat aagggaatga accctaacac cctgcaatac atcatgggac acgcaaacat
    11521 aaccatgaca ttagggtatt atgctcacgg tactttccag tctgcaaagg cagagttgga
    11581 aaggctggct tcttaatatc gaaaatgtat cttactactt atttactact tttggttgca
    11641 ttttcatgct ggtaaatgcc agcttatgcg aggtatcttc caaaaagaaa atgcccatac
    11701 agcccgaaaa tacgggatat atcggcattt accaacttat gaaaagataa tcagaaatta
    11761 gtaagttttt atatcaaaaa aatgattact gtaaagaaat cattttttat tataatcact
    11821 gatacatcaa atattctaaa taaaattttt atttatctgg aattgtatat tttttctata
    11881 atattaacta cagcgtacat tgcccaagca cagatagcca atacaaatac tcccatcatt
    11941 actaaatcta atttaaatac ttgagaacca tatactatca agtagcctat tccatatctt
    12001 gaaactaaaa attctccaac tattacacct acccatgcca taccaatatt aattttagtt
    12061 aaatttatta aatttcctgt gtttgcaggt aatatgagtt taaataatat ttgagattta
    12121 gtagctccaa aactttttaa catcttaatt ttttcttcat ctatattcat aaaataatta
    12181 taagctgaaa gtatagtaac aacaacagaa atcgttacag ctgttacgac gattccttct
    12241 attccagcac ctacccaaac tataattata ggagctaaag cagtcttagg aagagcattt
    12301 aaaactacca aaaatgggtc taatattttt gataattttt ctgaccacca aagagcaatt
    12361 gctaccaaaa tacctaatac agtacctata acaagaccaa gaacagtttc atatacagat
    12421 attccaatat gtttaaataa ttgaccacta aatgcatatt gaataaataa attgtaaata
    12481 tcacttggtt tgctaaatag aaatgtattt ataacattta agtcagctaa aagttcccag
    12541 attacaataa aaccaattaa aattaatagc tggtagaata atacatttct tttttctctt
    12601 tttacacctt taacatagtt tatatatcct tcagatcttt tattaagcct catgtgtatc
    12661 tagctccttc cataatatgt cgaaatactt ttgaaaatca ggaactttac gtgttttgag
    12721 aggcgttttt gttccatcca tgttaagttc aatatcgtaa atatttttta tggtagctgg
    12781 tcttttagat agtattgcaa ccttatctga tatgcttatt gcttctgcta tagctaaaaa
    12841 agtgcaacta attgcttaaa gaaacagaat tatcaacttc agcacccata taaacaatat
    12901 taagatttcc taaactgcta tcccaaacga tactattaat aatagtagat aataacaatc
    12961 tcttatcatc taaactggca ttatcaactt catcattaaa tctcttcaaa ttactaacaa
    13021 taatatcaat attaatactg tcactactaa tattgatgtt actagattcc aaaatattaa
    13081 tcttatcctt taaaatacta atctcattat ttaggctctc aatctgggaa actatataat
    13141 cagaagcagt actaccagta ttttttgcaa gctctataac taaattttta ataagtcttt
    13201 ccttatctaa aatttgattt ttaagtaaat tagtctcaga tttaaaaata ttaaaaacat
    13261 tatcagtctt aatgttatta ctattgaatg cacttataat agactcttct ttacaattct
    13321 taattttatc tataactaaa ctttcaacta atggaccatt aagattttta cagttgcaac
    13381 tatcagaccc aagtgttttt ttagtaccac aaatataata atactttaaa tccttgtcag
    13441 tttttttgcc tttataggta attctcatat tagaaccaca tttaccacat tttataagac
    13501 cagataaaag agcagttttt ccagttgata tccttggagt tttatcacga tttttatcta
    13561 attgattttg tacttcaagc catatttcag gttctatgac tccatggtgt tttgcaattg
    13621 ctgctattga gttagatgta tttttagcat aggtaaggat tccacatttt ctatctggag
    13681 tacctacaac atccatacca ctatttttaa ggtaatctaa aatttcatca ttagctttta
    13741 catatgctgg atttctaagt attctagata aagaactagg gtcaaatttg ccaccacgag
    13801 gaccccttat tccattatta tagacatatt tatataactt agataaggac ctaagttcta
    13861 aatatttatt gtatattagc tttacaatct ccatttgttc atcatttact tgaagcttat
    13921 acatacttct ttcttttaga ttttcatcta agaatgtgat tttttcactg ttgaatccat
    13981 gaggtgtatt gcctccaagc catctaccac tacgggctaa ttcatacata ttgtctttta
    14041 tacgttctgc tattgtttct ctttctaatt gagcaaatac acttgatata aacatcatag
    14101 ctcttcccat tggagttgaa gtatcaaatt gttctttgat agatataaat gatatgctta
    14161 gttcatttaa tttttctatt aaagtagaga agtcagatac atttctcgat atcctatcta
    14221 atctataaca aactaggtaa ctaaatttct tatctttggc atcctgcatc attttcttaa
    14281 attgtggtct atctatattg ctaccactaa atccctcatc ttcatatatc aaaaaatctt
    14341 ttacaccaat agactttgca taatcaatac ataattgtat ttgattttct atagaatcac
    14401 cttttccagt aaatcttgat tttcttgaat aaattgcagc tttcaaaatt aaaaccccct
    14461 ataagttagg atatatattt gaaactattt atctacaacc ttttaagtaa acttattaga
    14521 atgaatttat taattaggta aatttatata attctacttt ttataatata tgactattta
    14581 ttttatttct ttactattca agttctaaat caataataaa ttttgatatt taattgtatc
    14641 aggacaaatc tctaatttca tagattatta atataaaatc ataggttagt gtgaaaaagt
    14701 tgaaatttaa atattttaaa agataatttt tttgaactaa taggtataac aaaaatttat
    14761 agggggattg catatggaaa tcaatgttat agaaattttc cctaaagata aagctaaact
    14821 taataaaata gaaatggata aagctagttg gtttgtaaat ataataagta aaaaatatcc
    14881 taaagaagct ttaaatgaag catttagtac tttagaaaaa gaattaaata taagtaaagc
    14941 taatacataa gctttgatta ttgattttat atactattgg ttttatacgc tatgacttga
    15001 cattatatta atcaaatagt atatttttaa atatagcaca atgaagtgtt aaaagagcaa
    15061 tggagctcca tagataaagt ctatggagct tttttgcgta tttaacttaa ggaggatagg
    15121 actttgaata actttgagat taaaactaga ataaaatttg gagaaggctc actaaaagct
    15181 ttgcaagaat taaaaaacaa aaatgtacta ataataacag acccttttat ggtgaaatca
    15241 aaaacaatag ataaaataac atctaattta ataaactcaa catatcaagt ttttgaagaa
    15301 atagtaccag acccaccaat agaagtagta gtagcaggaa tagaagcatt taaatctata
    15361 aatccagacg taataatagc attaggtggt ggttctgcaa tagatgcagc aaaatctata
    15421 atggactttt ctaaaaaaat attaaaaatt aacgaagtag agtttatagc aataccaaca
    15481 acaagtggaa caggttcaga agtaacatca tttgctgtaa taacagatag tcaaaaaaaa
    15541 tgtaagtatc cattagtgag tgatgattta cttccagata tggcaatact agacccagaa
    15601 cttgtaaaaa ctgtaccaaa ttttataaca gcagatacag ggatggatgt attgacacat
    15661 gctatagaag cttacgtatc tacaaattct aatgactttt cagatgcact agctgaaaaa
    15721 gctataaagt tagtatttaa atacttaata aaagcatata aagatggaaa tgacatagaa
    15781 gctagagaaa aaatgcacaa tgcatcttgt ttagcaggta tggcatttaa ccaagcatca
    15841 cttggcataa atcattctat tgcacatgta ttaggtggaa aattccatat accacatgga
    15901 agaacaaact ctatattact tcctcatgta atagaatata attcatcaat agtaggatat
    15961 actaacacaa cttactctgc tacagctaaa aaatatgcac aaatagcaga attagtagga
    16021 cttgggagtg ctaatataag aatatctgtt agaaatttag taaatgaaat aaagaaacta
    16081 caaaaagaaa tgaatatgcc aactaaattg acacaatgca aattaagttt agaagatata
    16141 actaatgaag aaagagaaat agcaaaactt gctataaaag atacttgtac attaactaat
    16201 cctaaggtac caactgaaga tgatataata aacatattaa agaacattaa ataactacat
    16261 tttattacat gtaaatataa tattatacaa atagggaaaa tgtttttaaa aatataaatt
    16321 atatattgac aaatataaaa cataaaacta taatgaaagt atcacaaagg cgtgatactt
    16381 tagtagaaag caatggagct tcttaggaat attaatatta ttcttatgga gctcctttta
    16441 ttttaatcaa atagcttttt aataaactat attcaaagaa agcagggaat aaatttgact
    16501 gaagaatcta agcaaagagt tattcaagaa tatgttcctg gaaaacaggt tacattagca
    16561 catatcatag ctaaccctaa tgaagatata tataagaagt taggattagt acttgataaa
    16621 aaagatgcaa taggaatact tacaataaca ccaagtgaag cgtcaataat agcagcagat
    16681 gttgctacaa aggcttcaaa tgtatcttta ggttttatag atagatttag tggttcagta
    16741 gtaatatcag gtgatgtaag ttctgtagaa tcagcgttaa atgatgtttt agaagtctta
    16801 ggaaatatgt taaacttctc atctacaaaa atcacaagga cataataata caatgaagaa
    16861 tataatattt atgggaaaga caggtagtgg taaaactacc ttatgtcaaa aactagacca
    16921 gttagaatta aagtataaaa aaactcaatc agtggaactt tataataatg caatagacac
    16981 tcctggtgag tatatggaaa atagaaacct atataatgcc ttaataacaa catcagcaga
    17041 tgctaaaatt atagcaatag tgtatgatgc cacacaagaa gaaaattata tagcaccagg
    17101 ttttgccagt atgttttgca aagacgtaat aggaattata actaaaataa ataaagctac
    17161 tgaaaacgaa gtcaatatag cttatgaaag actatcacta gcaggagcaa gtcaaatctt
    17221 taaaatagac acagttgata atattggact tgaaaaatta tttaaatatc tagaaaaata
    17281 taaaaatata gatgaagttt aaggggaaat atttttttat tcaaaaatat tattaaagta
    17341 tgataaaata aaaaaatgta taaactattt taagaagatt taatctttaa gcgaggtagg
    17401 aacatgggga aaaaaatact attggttgat gatgaaccac tgttaaggat ggatacaaaa
    17461 gatatattag aaagtcatgg ctatgaaata ataggcgaag caagtgatgg atttgaagct
    17521 gttgaaatgt gtaaaaaaca caaacctgat ttagttataa tggatataga gatgccaata
    17581 cttgatggta taaaggcagg caaaataata tgtaaagaaa atatagctgg tggagtactt
    17641 ttattaactt catttgaaga taaagaatac gtagaaaagg ctaaaagtat aggtgcttat
    17701 ggatatttag taaaaacagc aagtgaaaaa tcacttatcc caaccataga aatgtgttta
    17761 aataaggtaa atgaatttga aaaaatgaaa aaagatttag aaaaagtaaa ttctaaattg
    17821 aatgaaagaa aattagtaga aagagcaaaa ggtatactta taagagagtt taagatttct
    17881 gaggatgaag catacactag aataagaaaa ttaagtatgg ataaaagaac tacaatgatg
    17941 gaaattgcca aaatgattat aataggatac gatgactaat acgataaaaa aaatatcaac
    18001 tgcacaaaca tacttaaata ataacgaaat tgaaaaaatt atagaagtat caaaatcctt
    18061 agatttaatg gcttcttttt atgaagctga tgtttttata gatgtactaa gtaaatttga
    18121 tgatgaagca attgttgtgg cacatggtag acctaaagaa aagtcaatgt actgtgaaaa
    18181 tgttataggt aaaaaggctt taattgaaaa tgaaccagga gttataaagt gcttaaaaac
    18241 aggagaaaga gtaagagata ttaaagcttt aacacaggaa tataaactgg tcaaacaaaa
    18301 tattcagcca ataacactag atgacaaagt tttagcagta ctaatagttg aaaaagatat
    18361 aagtagtgaa gttaagaatg agtttaatgc tagtgaagac gaagaaaata aaaatttaca
    18421 tcagtttata aaacttattg gaaataatga ctttttagtt gataatttaa attcagccat
    18481 attaatattt gataaaaatg gaaaattaaa aattaaaaat cgtattgcaa ctgagatata
    18541 caaaaatctt gggtttggat atgatataca agatatgcat tacaatgatt tagatataga
    18601 aaccaacacc tttgaaaata tattaatgga tgaaaattat gatgagacaa atgaagtttc
    18661 aataggtaat atgtttttta aaataaagac catatacatc aaagatgatg aatttaaggt
    18721 ttgcaaaata gtacaagata taagtgattt aaagagaaaa gaagaagaat tagttttgaa
    18781 aacagtggct ataagagaag ctcatcatag agtaaaaaat aatcttcata cagtaatatc
    18841 tataataaaa aaacaaagta gattatctca aaatgatgaa gtaaagcagt gtttagataa
    18901 cataataaat agggtatttg caatactttc gactcattat ttactatcta aagaagttga
    18961 taataatata tctatacgag aaggtatcaa tttattagtg tcaaatattc aaggtggcta
    19021 tttatttagt aaggatatag atatacgtat aactggtgaa gattttaaaa ttagtggaga
    19081 aaaagcaaca gcaatacttt tggttataaa tgaaatacta caaaattgtt atgaccatgc
    19141 attttcggat agagaacatg gtactataca aatattaata aataaagata acgactatag
    19201 aaatattgct attatagatg atggaattgg atttgatagt aataatataa ataaaaatag
    19261 cttagggaca tatataatag atagttatat aacacagatg ttaaaaggaa atatagagag
    19321 aaaaagtagt gagaatggta cagaagtatt aattactata cctacacaaa ttaatattta
    19381 aataataact catctacaaa gtagtagttt taattgagca aagaggctta aggttattaa
    19441 tagattaagt taattgaatg tatttataaa aattataagt atatattcaa tttaacaggt
    19501 atttattata actttaagcc tctttgcttg tttaagacat acttaaattt taggaggtga
    19561 gaaaatgaga gaagagttat taagtgttgg tattgacatt ggaacaagta ctactcagtt
    19621 aattttttct aaattaatag tagaaaatac tgaatcaaat ttttcggtac ctagaataag
    19681 tatagtagac aaagaaatta tttataaaag caaagtttat ttcacccctc ttatttcaaa
    19741 taatgaaata aatggtcaac aaataaaaga tatagttgaa aatgaatata aaaaagcaaa
    19801 tatatctaaa gaagatatac atacaggagc agtaataata actggtgaaa cagctagaaa
    19861 agaaaatgca aatgatgtac ttcatacttt gagtggattt gctggggact tcgttgttgc
    19921 aacagcagga cctgatttag aaagtataat atcaggaaaa ggagctggag ctcatattta
    19981 ttcaaaagaa cattcaacta caattgtaaa tatagacata ggtgggggaa ctagtaacat
    20041 agcctcattt aaaaggggag aagtaaccga tactgggtgt ttggatatag gtggaaggct
    20101 tgtaaagata gataaaataa gtaaaaaaat aacttatata tcacctaaaa tagataaaat
    20161 cataaaagat aataatttaa atcttcaagt aggtacaatg gctactgtag aaaatacaaa
    20221 gccaatagtg gatataatgg ttgacttatt aatggaaagc ataggactaa agaaacagac
    20281 acctttgttt gattttataa taaccaataa atcaataagt atagatgaaa atattaaaaa
    20341 tgtttcattc tctggtggag tagctgatta tatttactat gatggagaaa taaaagatta
    20401 ttttgaatat ggtgacttgg gaattttact tgggcaagca ataaaaaatt gtgaatacct
    20461 taaaaaagta aatgtagtta aatctatgga aacaataaga gccacagtgg ttggagcagg
    20521 ttctcatact actgaagtaa gtggaagtac aataacttac actagcgaaa agtttccact
    20581 taagaacttg ccagttttaa aattatcaat tgatgaagaa acaggtactt caaaacaaat
    20641 cagtgaagct ataaaaaata aacttaattg gtttaaacta gaaaatgatt tacagaaagt
    20701 tgctatagcc atgataggaa agaaaaatcc aaccttttta gatatacaag agtatgctaa
    20761 agggtttgta gatggaatgc aacaaatcat agaaaatgat ttacctttta tagtaattgt
    20821 tgaaaatgat atggcaaaag tgttaggtca agcaatatat gcattattaa attatgaaaa
    20881 agaaattgtt tgtatagaca gtgtcaaggt tgaaaatgga gactatatcg acattggaaa
    20941 acctatagtt gaaggtaaag ttttacctgt ggtaataaaa acattagttt ttaattaata
    21001 gaaggaggta agtaaatgat tttaaataca aaattatttg gacgtactta tcagtttaaa
    21061 ggcttatatg atgtaatggc taaagctaat gaagaaaaat caggagataa attagcaggt
    21121 cttgcagcag aatcagctga agaaagaata gcagcaaaag ttgttttatc acacataaaa
    21181 ttggaggata taagaaataa tcctgcagtg gcatatgaag aagatgaagt aacaagaata
    21241 atacaagatg ctgtaaatga aaaagtttat gaagaaataa aaaattggac agtgtctgaa
    21301 cttagagaat ggctattgga ttcaaatact acaagtcttg atataagaag aatatcaaga
    21361 ggattaactt ctgaaatgat agcagcagtt gcaaaattaa tgtcaaatat ggacttagtt
    21421 tatgcagcta aaaagataaa ggttactgct cactgtaata caactatagg agaacaagga
    21481 acattatcag caagacttca acctaatcat ccaacagacg acccagatgg aatacttgca
    21541 tcacttcttg aaggtttaac ttttggtata ggagatgcag tacttggatt aaatccagtt
    21601 gatgactctg ttgagagtgt tactaaagta ttaaaaagat ttgaagaagt aaaacaaaaa
    21661 tatcaaatac caactcaaac atgtgtattg gcacacgtta ctacacaaat ggaagcaata
    21721 agaaatggtg ctcctgcaga tttaatattc caatctatag caggttctga aaaaggaaat
    21781 gaagcatttg gatttaatgg cgacactata gaagaagcta gacagttagc cttaaaacac
    21841 ggtacagcta caggacctaa cgttatgtat tttgaaactg gacaaggttc agaattatct
    21901 tcagaagcac atcatggaat agaccaagtt actatggaag ctagatgcta tggatttgct
    21961 aaaaagtatg aaccattctt agtaaataca gttgttgggt ttataggacc tgagtactta
    22021 tatgatgcta gagaagttgt aagagcagga cttgaagacc actttatggg taaactacat
    22081 ggcttaccaa tgggtgttga tgtttgttac actaaccata tgaaggctga ccaaaatgat
    22141 atggaaaact tagccatact attaacaaca gcaggatgta cgtattttat gggaatacct
    22201 catggagatg atgttatgct taactatcaa acaacaggat accatgaaac agcatcactt
    22261 agagaaatgt ttggactaac agcaataaaa gaatttgatg cttggatgga aaagatggga
    22321 ttctctaaag atggtaagtt aacagagttg gcgggagacg catctgtatt attaggatag
    22381 gaggtattta atatgaatga gaaggattta aaagcattgg tagaacaatt agttggacaa
    22441 atgcttggag aattagatac taatgttgtg tctgagactg ttaaaaaggc aactgaagtt
    22501 gtagtagaca acaatgcttg tatagatgat ataacagaag ttgatataag aaagcaatta
    22561 ctagtaaaaa atcctaagga tgcagaagct tatttagata tgaaagcaaa aacacctgca
    22621 agattaggta taggaagagc tggtactaga tataaaacag aaacagtttt aagatttaga
    22681 gcagaccatg ctgctgcaca agatgctgta ttctcttatg tagatgaaga atttataaaa
    22741 gaaaataata tgtttgcagt ggaaacttta tgtaaagata aagatgaata cttaacaaga
    22801 ccagatttgg gaagaaaatt ttctccagaa actataaata atataaaatc taaatttggt
    22861 acaaatcaaa aggttttaat attagttgga gatgggctta gctcagctgc aatagaggca
    22921 aatttaaaag actgtgtgcc agctataaaa cagggtctaa aaatgtatgg tatagattca
    22981 agtgaaattt tatttgttaa acattgtaga gttggtgcta tggaccactt aggtgaagaa
    23041 ttaggttgtg aagttatatg tatgttggtt ggagaaagac caggattagt tactgctgaa
    23101 tcaatgtcag catatatagc ttataagcca tatataggaa tggcagaagc aaaaagaaca
    23161 gttatatcaa acattcacaa aggtggaaca actgcagttg aagcaggtgc tcatatagct
    23221 gaacttataa aaactatgtt agataaaaaa gcttcaggaa tagaccttaa ataaagtcga
    23281 gggagtgtag aatatgaaaa atgatgtaat tcgtcctaat atactaggaa ttaaaataat
    23341 ttcaaatata agtccagaaa tggcacaaaa actagaatta aaatcacatc acaaaagctt
    23401 aggtttaata actgcagact gtgatgatgt tacgtataca gctcttgacg aagcaactaa
    23461 agcttcagaa gttgatgttg tatatgcaaa atcaatgtat gcaggtgctg caaatgcttc
    23521 aacaaaactt gctggtgaag tattaggaat aatagcaggt ccaagcccag cagaagtaag
    23581 aagtggtcta aatgcagtag ttgattttct agagtatgga gcaactttta taagtgcaaa
    23641 tgatgatgat tcaatagcat actatgctca ctgcgtatca agaacaggta catacctttc
    23701 agaggtagca ggaataagag aaggtgaagc attagcttat ttagtagcac caccacttga
    23761 agcaatgtat gcactagatg cagcaatgaa agctgcagat gttaagatgt gtgaattatt
    23821 tgcacctcca actgaaacaa actttggtgg agcattactt acaggttctc aatcggcttg
    23881 taaagcagca tgtgatgcat ttgcagaagc agtaaaatca gttgcagaca atccaacagg
    23941 attttaagga tagttagatg gatgctatag gcttaataga agtaatagga tatgttgctg
    24001 caatagaagc ttctgatgct tgtttaaaat ctgcaaatgt taatattgta agagttgata
    24061 aggttggggc aggtattgtt actttaacaa tatgtggaga tgtcggtgct gtaaaagctg
    24121 ctttagaagc gggtgaaata gcagcttcca gagttggtac attaagaaca tcacatatta
    24181 taccgagaat ccataatgaa gtaacaaatg ctttattcaa aactaaagaa cctaaagtct
    24241 gtgaagtttc agaagataaa gaaaaaaact ttgagattac attggaaata gctgataatg
    24301 tatcgaaaaa tttatcagaa aaagaaaatg taattttaga tgtcaatgaa aacagtggag
    24361 atactgaaaa tttatatagt gatatagata aaacaaacaa aaaaattgaa acagttgatg
    24421 atagtttaac agaagctaat gaggaaaaaa tagaaaacac taatgataaa gaagtattgg
    24481 aacaagttaa aatagaaaat tccgattttg atagagatga cctatcaaag aacagtgtaa
    24541 aaaaacttaa agctatggct aaaaaattag attcttcaat aacttataaa gacttaaatg
    24601 ttcttaaaaa agaagaatta ataaacttag ttaaaaagct tagcagaagg gatagatagt
    24661 tatgacactt ttagataaag atttagtatc tatacaagaa gtaagaactc ttgtaagaag
    24721 atctaaagtg gctcaagaga aactttctaa aatgagtcaa gagcaaatag ataaaatagt
    24781 aaaagctgtt gtagatgcag catttaataa tgctactaaa ttagctaaaa tggcaaatga
    24841 agaaactgga tttggaaaat gggaagataa agtaattaaa aatacttttg catctatggg
    24901 agtttatgaa actttaaaga acacaaaaac tattggaata attggtgaag ataaagaagc
    24961 caatacgata gatatagcta caccagttgg agttgttgca ggtcttatac cttcaacaaa
    25021 cccaacatca acagtaatat acaaaactat aatatctcta aaagcaggaa atactatagt
    25081 tttctctcca catccaaatg caaaaaactg catacttgaa acagttaata taataagtga
    25141 ggctgctata aaggctggag ctccagagga ttcaatatta tgtataacta atccaagtat
    25201 agttggaacc aatgaattga tgaaacataa agatacaaac ttaatactag caactggagg
    25261 agaagcaatg gttagagctg cttactcttc aggaacacca gctattggag ttggaccagg
    25321 aaatggacca gcatttatag ataaatcagc aaatgttaaa ttagcaatca aaagaataat
    25381 agattctaaa acttttgata atggtgttat atgtgcatca gaacaatcta tagtaataga
    25441 aaaatctatg gaagaaactg ttttaaaaga gcttaaaaat caaggtgcat atgttttaaa
    25501 tgaagaggaa agtgaaagat tagcaaaatt catattaaga gctaatggta ctatgaatcc
    25561 acaaatagtt ggtaaaagtg ttgaggtaat agcaaattta gcagacttaa caaatgtacc
    25621 taaaaataca aaagttctag ttgcaagaga aaataaagtt ggtcacaatg tagcctattc
    25681 aagagaaaaa cttacaccaa tactagcgtt ctatgttgaa gaaaatgtag aagctattat
    25741 gaacagatgc agagaaatat tgttaaatga aggtgcaggt catacattct caatgcatgt
    25801 aaatgatgaa gaattggtaa aaagatttgc ccttaatatg ccagtatcaa gaatacttgt
    25861 gaatactcct tcagcacttg gaggaatagg tgcatcaaca aaccttgtac cagcactaac
    25921 acttggttgt ggtgcaatag gtggaagttc aacttcaaac aatataggac cacttgattt
    25981 aataaatgtt aaaagagtag cttatggaat caaagaaata gaagaacttg gaagagataa
    26041 atctcaagtt gaaaaatcaa tgtttgactc aatggataaa gaagaattaa taaatcttct
    26101 tgttcaaaaa ctagtcaaag aactagcata actaaaataa acaatgaaac ttatggctat
    26161 cgctataaat ttctaaaaat ataaactata aaaaactata aaattaaatt tttggaggat
    26221 aagattatgg caagtgcaaa cgcattagga atgatagaaa ctaaaggatt agtaggagca
    26281 atagaagcag cagatgcaat ggttaaagct gcaaatgtac aattagtagg aaaagagcaa
    26341 gtaggtggag gattagttac tgtaatggta agaggagatg ttggagctgt taaagctgct
    26401 acagatgcag gagctacagc tgccgagaga gttggagaac taatatcagt tcatgttata
    26461 ccaagaccac actttgaagt agatgctata ttaccaaagg tatcagctga gtaatataag
    26521 aataattata aaatttaaat tttgattgaa aaagaggcta tctcaaaaat gagtcttact
    26581 aataaactca atgtattttg aggtagtctt ttttatacat ctaataggag atgtgataaa
    26641 atgggtgttt taacagaaaa cgaagtaaaa agaaaaattg gaaaaaacaa aaataatata
    26701 actgaatttt atatagaaaa aggtcaaata ataactcctt ctgcaaaatc ttatttagct
    26761 gagagaagta ttgagcttaa atatgttgat aaactttcag atgtaaacaa tgaacctaaa
    26821 gaagttgtaa aagaagtagt taaagagaaa aaatataaat atactactgt atttggcgcc
    26881 aaattggatg aaaaaccaga acatatgact caattaaatg gaaatctttt agtttttaaa
    26941 gaccataaaa gaataatatt gagaggaaaa atagattctc ttgaatcaga aatactaaag
    27001 gtacagatac tttgtcagaa actagatatg ccaaagcttg ttaaggaatt gcaagaagta
    27061 ttagactttg taagaaatat aatgagatgt gaagttttag atgaaaagct aggggacttt
    27121 aaacttttag gattaactcc tcaagaactt agagaacaat ctcactatcc taaaaaatac
    27181 tttggtatag gacatgagtt cccaagttat gaaatgggag aagtagtagt agctataaat
    27241 agtataagaa gtaatacacg agaggttgaa cttgcagcct atgaagcatt taagggtgag
    27301 tatggaaatg ttcacagaga agatttaata aaggcactta atagattatc gtcagtattt
    27361 tggataatga tatataaggt tagaactaat aagtataagt agttggagga cataatggag
    27421 aatctattaa atgaaatagt ggaagaagta ataactagag ttaaaaaaga agcatttata
    27481 gaagttgaag catcaggaag acacgttcac ttaagtagag aagatgtcga taaattattt
    27541 ggagaaggat atactcttac aaaactaaaa gacctatctc aaccaggtca atatgcatgt
    27601 aaggaaagag ttacaataac tggtcctaaa ggaagtataa aaaatgtagt tgtacttgga
    27661 ccatgtagaa atgaaactca ggtagaaata tctttaacag atggttcaac tcttggacta
    27721 aaagctccta taaaacaaag tggagactta gaaggtactt taagtattaa aatatcaaca
    27781 caatatggtg aagttgaact tgataagggg ctaatggttg ctaaaagaca tatacacatg
    27841 actcctaaag atgctgaaaa attcaatgta tgtgataaag agatagttga agctaaggtg
    27901 atgggtcaaa gacctttaac atttgatgat gtagtaataa gagtgagtga cagttttaaa
    27961 acttatatgc atatagacta tgatgaagcc aatgcatgtg gttattcaaa aggaactgtt
    28021 gctaaaataa taaagaaagc ataaatttaa cctactatat aaattacctc tagggaggat
    28081 ttaatatgaa ttatgataac cttgtagatt taataacgga agaaatctat aaaaaaataa
    28141 atagtaatga aataaaaata tctaataaac ctaaagctgt gattgtattt gaacaagata
    28201 acaataaatt taacttatta aaagatggat ttgaaatagt agaatttgat aaaagtataa
    28261 gggaatgtga aatagtgata gtttcaagac tttgtatgag ggggctatcg aatatagcac
    28321 ttggaaattc aacaagtgat gaagaaagat ttatactaaa aatgattatg aatggcaaaa
    28381 aagtatatgt cctagatgaa ggaattgaat acaaaaaata taaggatact gcaccaaaag
    28441 cactatataa gaaatttatg tcatttgaag atgaaatatg taaatttggt gtagaaatta
    28501 taaaagactt aaatgttata actaaaaata agttaaatat aaagaaagaa ctagaaagta
    28561 ctagaggttc taaaaaagaa gatacaaaag ttttagataa agatatttta aatttaacca
    28621 gtgtagaaag tgtaaaaata gataatgaat ttagtttgga tttaaggaat aaaaaactta
    28681 tatcggaagc tgacttaaga aaaccaacta taaatggagt taaaaacata ttagttaata
    28741 aaaaaagtat aataacacca ttagctgtag attttatgag aatacaccat ctcaaactaa
    28801 agaaactgta aggaggtaat tttatggata taggaaaagt tgtaggtaat gtttgggcta
    28861 caagaaaaga tgaaaaatta tgtggccaaa aacttttagt tgtaaaaatt ttaaaaacta
    28921 aagacacata caaggaaggc ttcatggttg cagccgataa tgcaggagca ggaaatggag
    28981 acttagttct tatatccaaa ggttcctcag ctagagagtc gattgaaaaa tctcatgttc
    29041 cagtagatgc aactatagtt ggagtagtcg attcgtttga ggtgtttgat gaataaaagt
    29101 ataggagcta tagagtttaa aagcattgct aaaggtatag aagtatccaa tgaaatgata
    29161 aagaaatctt cagttgatgt attgtactta aaaagtattt gcccaggtaa atttctaata
    29221 atagtaggtg gagaaacttc ttatataaat gaatgtgtag attatggaat aaaacttgga
    29281 gaaggatata ttgtagataa cttcgtaata aatgcaattt cacaagaaat attagatgga
    29341 tttaaaaata agtatcaaaa gctagatagt atagtctcta taggcgttgt tgaaagtagt
    29401 aaaatatgcg ctggaataaa aatgcttgat aagactttaa aatctggcga cttagtatta
    29461 gtaaaacttc aattatcttt tgctataggt ggcaaattag tatatatagt agcaggagat
    29521 ttaagtagtt tagaatatgc attaaaagaa agtgaaaatg tagtaagaga aaaagaagta
    29581 atatataaga ctgtaatacc atcagtagac agtcaaataa taaaaagtct aataaaataa
    29641 tggggggaat tatgagtata aacgaaatta taatctatgt aatggtagtc ttcatggtac
    29701 ttggagctat agataaatgt ataggtaaca aatttggtct tggagaacaa tttgaggaag
    29761 gtataatggc aatggggtca cttgcagttg caatggttgg tgttatatgt ttagcaccag
    29821 ttcttgctga tgtattaaga ccaattgtag taccagtatt taatatactt ggagctgacc
    29881 cagctatgtt tgctggaagt ttattagcta atgatatggg tggtgcgcca cttgcacttg
    29941 aacttgcgaa agaccctaat gctgggttat ttggtggatt aatagtaggg gctatgatgg
    30001 gacctacaat agtatttata ataccagttg cgcttggaat aattgaaaaa gaagaccaaa
    30061 aattcttagc aacaggaata cttgcaggta taataacaat acctattgga gcattcgttg
    30121 gtggattagt tgcaggattc gaggtaatga tggttcttag aaacttagtg ccaataataa
    30181 tatttgcagt agttatagca cttggattat taaaattcga aaatgctatg ataaaaggat
    30241 tcacatactt tggaaaaggt gtagtaatag ttataacttt aggacttgct gctgccatag
    30301 ttgaagcttt aacaggaata gttgtaatac ctggaatgaa accaatcagt gaaggtatag
    30361 aaatagttgg agatatagca atagttttag caggagcatt cccattagtg tttgttataa
    30421 caaaggtatt taataaacca ttaatggctt taggaaaagt tcttggaatg aatgatgtat
    30481 cagcagcagg ccttgttgca agtttagcta actgtatacc aatgtttggt atgatgaaag
    30541 atatggacaa tagaggaaaa ataataaatg tagcattctc tgtatcagca gcattcgtat
    30601 ttggagacca cttaggattt acggcaggat ttaattctaa tatgataaca ccaatgatag
    30661 ttgctaaatt agttggtggt ataacagcag tattgttagc tatggttatc gcaaataaga
    30721 cactaaagaa ggagaatgta taagatggat atatcaaata tagataaaaa tttaattgaa
    30781 acattagtaa gacaaataat agaagaaaaa ataagtggaa ctaaagacac agtagatttt
    30841 gttagaaata aagacattag tggaataact tctataaagt taccaactgt aaaagttagt
    30901 gaatctgata gattagatac agggaatcca agtgatgtag tttacacaaa agatttattt
    30961 acattagagg aaagcccaag attaggttgt ggtatgatgg aaatgaaaga aacaactttt
    31021 gattggactc taaattatga tgaaatagat tatgtaatag atggaacttt agatataata
    31081 atagatggaa gaaaggtttc tgcttcttca ggtgaattaa tattcatacc aaaaggaagt
    31141 aagatacaat tttctgtacc tgattatgct agatttatat atgtaacata tccggcagat
    31201 tgggcatctc aaaattaata aaaatcaagt taagttaata atcaaataaa taatttaaaa
    31261 tacaaactct taaataagca cgcatattta aaaaagctat gaattaaaat tcatagcttt
    31321 ttttataaag aatgttatat tttagacgta ttttttctat atttactggg agatatatta
    31381 tattttttat taaataatct aataaaatgc tctacatttg gataaccaat actattttac
    31441 tgataatctt ttccttatca ctaatcttac attttaaaat attattttta ctcgtaatat
    31501 tatcataaga atttgtttct tatttaaaac taattagaat tataaagttt attgccatgt
    31561 tattaataaa ataaatccag ttaaatcgag tgctagttaa agtaataaga aacttttaca
    31621 atggtttcct ttatcgattg aaataaaagt taatatggta taatatctaa agagagaatc
    31681 ttatcaatta gaatatgcat agaaacaagt ggcttaaaag gagacgttat atggaagaga
    31741 tagtaaagaa ggaacaagca agtatgaatg atattttttt gtatcttaaa gctaaatcaa
    31801 actcattata taaatttgta atattatata atgagtttat caataaacct aaagattatg
    31861 gaactgggga acttataaac atggttgaag tacatatgct aacagcgatt gaagaaaatc
    31921 caggaataag tccaactcag ttagctaaaa tatggaacag aactaaaggt gcaatatctc
    31981 aaactatatc taaattggag aaaaagggtt atataactaa agaaaagaaa gaaggaaatg
    32041 caaaaactat attactatat ccaaccacat caggagtaga gttaagtaag gcacataaac
    32101 tatatgacac catagatgtt acaagaacat ttgaatactt aatcaaggag tgtacattag
    32161 aggagataga tagtttttat aaagtaattg atttgtttat taatttatta gaagaatctc
    32221 cgcaggaaaa taatgattct gaaaaagtgt agctgagatt gaagttgaat aaagagaaat
    32281 agatattata gaagtagtac ttaagtacac attatataaa aatataatag gtataggatt
    32341 aaaaagttta gtggtttaaa gtttaaccac taaacttttt taatgtctat aatctactat
    32401 tatttaattt actaaaaata aaaaaactca ttatattaag atagaaatag aaaaataact
    32461 agaaaaatac tataatatat cagcttaata cagaaaaaag ttaaaaaatt tgagaaaaat
    32521 aaaaatgaaa acgttttata ttgacataga gaaaaagtag tgataccatt taaatatagt
    32581 ttagtagcta aactatattt aaattataat aactatttta gggggatgtt atgaatttaa
    32641 aacaattaag tgaaaaatac gaagaatatg taattcaaat gagaagagaa tttcataagt
    32701 atccagaatt atcttttaaa gaaataagaa caacccaaag aataagggaa gaattacaaa
    32761 aaataggggt cccttttgta tctattgaac caaatatcgt aatagctact atacaaggca
    32821 aaaatgaagg taagacaatt gcaattagag gagatataga tgcgcttcca atgcaagaag
    32881 attcagatgt tgaatacaaa tcagaatatg atggaataat gcattcttgt ggacatgatg
    32941 ctcatggagc tatgttacta ggacttgcac atatgctaaa tgatataaga aaagatttaa
    33001 aaggtagagt attattagtt tttcaagcag ctgaagaagt tggtggtgga cacaaggaga
    33061 taatacagta ctttaaggaa aatggaggac cggatagatt aatagctact catgtttggt
    33121 ccgatattga agctggtaaa atttctgttg aaccaggacc tcgtatggct ggtgggtctg
    33181 gttggagaat agacataaca ggtagaggag gtcatggttc tagaccagat caaagcatag
    33241 atcctataaa gccagcttgt gatatagttt taaaagtatc ttctatacca gttaatcata
    33301 taagtgtact agaacaatgt gttgtacatg catgtgcaat acatggagga actacaatag
    33361 gaaatgttat tccaaacaat gcagaggtaa taggtggata tagatatttt actgaagaat
    33421 caggcaaaaa agtgtttgac attataaagc aaatgagtaa tggtgttgga caagtttatg
    33481 gagtggatgt gaaggttact catactggag gcataggacc tgttatcaat gatgaagaag
    33541 cagttaagat ggctaaagaa atagtttcta atatagatgg attggagtta gattcttatg
    33601 agccaatatg tgcatcagat tgttatggtg aaatattaaa agagtattct ggcttttatt
    33661 gttatctagg ggtaggtaac aaagaaaaag gaataatata tgcacaacac catcctaagt
    33721 acaatataga tgaagatata ttaaagttag gttgcgaatt tatggctaaa tatgcagttg
    33781 aatttttaaa taaaaataat aactaaaata aatctaattt tataaatggg gggatgaaaa
    33841 tgcaaggtgc attaaaggaa aataagaaaa aaagtggtgg aggattttta ggatggattg
    33901 aaaaagttgg gaataaaatg ccacatcctc tagcattatt tacatatatt acactgatag
    33961 tagtagcatt atctgcaata gcaagctttt taggtttttc agcaacaagt cctgctacag
    34021 gaaagttaat aaaagttatg aacttaataa gtgcaaaagg tttagtacta tttatgcaag
    34081 agtttgttaa gaacttccaa aacttccctg tgcttggagt agttttagtt atggcagttg
    34141 ccacaggagt ttgtgaaaag acaggatttt tttcaactgc cataaaaatg agtttatcaa
    34201 aagttaaggg gaatgcggtt gtatttataa tagcttttat aggagtattt gctaatcaag
    34261 ctggtgatgc tgcttttgta ttagtaccaa ctcttgcagg agcaatattt tatggattaa
    34321 atagaaatcc attagctggt atattctgtg gatttgcatc agttggtggt ggatttgcaa
    34381 cagctgtaat tcctggggga tgggacgtta cgctaacgcc aataactgta tcagctgctc
    34441 aaactattca acctgcattt gatatgacat tattagctag ttattatgca ctatttgtat
    34501 ctgcgtttat agtagctaca gtatcaacaa tagtaacggt taaatttata gaacctaaat
    34561 taggtaagta tactggtaaa ccagaaggta tagatgataa tcaaggtttt gaggtcacaa
    34621 aagaacaagc aaaagcagca aagttagcag gttttacagt tttagcttat gtagcgttat
    34681 taattgcttt gtgtatacca gctaatagtt ttttaagaag tccagaaggt tctttaatat
    34741 ttggagcacc acttatgtct tgcttacagt tttttatagt aatactattc ttcttgccag
    34801 ggattgtgta tggaatgagg gttggtaaaa tcaagactgt aaaagactta aatgatatat
    34861 tatgtcaatc aatggcagca atggcaccgt ttatcgtact tgcaatagtt ataggtcaat
    34921 tcttaacgct attctcagtg tctaatttag cacaggtact agctataaaa ggtggagcat
    34981 tactcaactc attgccacta ccaccacaag ctataatact gctattctta gtactagtag
    35041 cgtttataaa tatatttgtt ataagcggaa gtacaaaatg gatgatattt ggaccagtat
    35101 ttgttccaat gttaatgcaa ttaaacatac atccagcatt tactcagttt gtatatagat
    35161 taggagattc tgtaaccaat catttatcac cattaaatgc attctttata atacttttag
    35221 caacagtcca aaaatacgat aaaaatgcag gtatgggaac tatattctca gctatgatac
    35281 cttacactat aggttacttt gtagtacttg cagttttagt agtagtttgg atgacaatag
    35341 gtataccagt aggaataggt ggacaagttt ggttataaaa catatttaat aattttggga
    35401 ggaaaaaaaa tggaaacaac tgaaataaga tacaattttg atgaagtaat agatagaagt
    35461 ggaacaaact gtcttaaata tgatcttaag agtcaattta tgccagaatc tccagaagat
    35521 gcactaccac tatgggtagc agatatggat tttgcatgtg cccctgagat aattaatgca
    35581 atgcatgaaa gaatagacag aaaaatattt ggatatagct ctcaacaaac tgatgattat
    35641 tatgaagctg tatgtggatg gtttaagaga agatttgatt ggaaaataga aaaagagaat
    35701 atattcttta gcccaggggt tgtgcctgcg ttaggatttt tcacacaaat attaacacaa
    35761 aagggtgatg gtatcataat agaaaagcct gtatactatc cttttgaaga taaaataact
    35821 aacaatgaaa gaaaagtagt taatagtcct ttaaagtttg aagatggtca ttattctatg
    35881 gattatgatg gatttgaaga attagctaaa gatgaaaata ataaggtgtt tatattatgt
    35941 agtcctcata atccagttgg tagagtatgg aaaaaagaag agcttagaaa aatagtagac
    36001 atatgtaaga aatatgattt gtggataata tctgatgaaa tacattgtga tattattcgt
    36061 aaaggtgaaa agcatatacc attagaagta gcatgtcctg attataaaga tagaataata
    36121 acttgtacag ctccaagtaa gagttttaac ttagctggta tgcaattatc aaatatagta
    36181 atcaataata aggaattaca agaaaaatgg atgcttgaaa cagattctaa attagctata
    36241 ttcctaccta atccattcgc aatagttgct actaaagttg cttataatga ttgtgaagat
    36301 tggatgaatc aagtaaatga gtatatagat ggtaatatta aatatgtaga agattttgtt
    36361 aatgagtata tgcctaaagt aaagataata aaatctcaag gaacttactt agtttggtta
    36421 gactttagag ggtatggatt agatgcaaaa cagcttgaat atgtaatgct taacaaggcg
    36481 aaggtattgc tagatgaagg atacatattc ggagaagaag gagcaggatt tgaaagaata
    36541 aatgttgctt cacctagaac aattatagaa gagtgtatga atagaataaa atgtgcattt
    36601 gaaggattat aatagtaata tctaaataat atatttgtgt attttaaaaa aagactatgc
    36661 taaaaaaata tttcaaagca tagtctttta aagttttatg atgagtttaa aaaatttcaa
    36721 aacgttacta ttcacttata tgtttatatt agaaataatt ccacaatata ctcattttct
    36781 aaagttgcac ttttatacac cttgcttcac caatatcatg tgtaaccaaa atagtagact
    36841 tattctcatt cttaataata ctataaacat catcacaaac taataatcta gtctgataat
    36901 caagagctga aaaaggttca tctaaaagta gaatatctgg atttacagaa agtgttctaa
    36961 taagcgcaac tctttgtctc atacctccag ataattcttt tggatacata cttctaaaat
    37021 cccataatcc ataagtcttt aaaaggcttt caactctatc taaagatttt ttatcttttt
    37081 tgccttgaat ttccaatcca atagttatat tatccattat atttctccat tcaagcaaat
    37141 tatctttttg aaacatatat ccaatatttc cagtaatctt tatatcacca ctagttggtt
    37201 ttaaaagatt agtaagaata tttaatattg tagatttacc acttccagaa ggaccaagca
    37261 aagttaatat ttctccttct ttcaagttaa aattgacatc ctttaatact tcaagctcgc
    37321 cttccttagt gtagaagttc atatttatat ttttaacttc tactatgttg tcattcatta
    37381 tgccaccccc tataactttt agctcgtata tattatgtta ttaacaatat gacctatttg
    37441 taccattttt cataaatata atataaatat tttgtttatt tacgtatttt cttagtaact
    37501 tgtacgtata aattatagat aaataaatta taaggtaggg gataaatttg agtaacataa
    37561 taacgaattt aatagagtca atatttacta atccaataac tatattgttt ttacttgcaa
    37621 taactgtgta ttctgttttt aaaataatag aaaataacag agtatattca tttgtaagtt
    37681 caaaattaga cgaaatcaat agagactata agacaagtga gttttataaa aaggtaaggg
    37741 atgactacta tacatatagt aaagaaaatc cttatgcaga cgtaaatata acttcattta
    37801 tagaggaagt tgtatctgat ttaaagcata ataatttgcc attgttagaa aaaattagaa
    37861 gtataaaaaa ttcatcttca ataagtatat tacttggggt tttaggtacg tttgttggtc
    37921 tttctacaat gcttttatgt gttgatacta aagacattat aaattcactt ccttcaacta
    37981 ttagtagtat gcaaactgca tttacaacta gtatatttgg agttgtattt tctctaatta
    38041 taggttattt tactaagata aaagattgtg aacatgtttt gatacaaata atgttaaaat
    38101 ctgaaaattt actaacatct gaaataactc attttaagtc agaaagaatg gatttaaaag
    38161 tagaagaggt aaaaaataca ataaaacaaa taagtaagtc tatagaagct attgaaaaat
    38221 ttgataaaat atctaaagat ttaaatgact ttaatgatga atttatcagt ggtatagaag
    38281 ctttaaaaag ccttttagaa ggttctcaaa gttctattaa gacatttgac cagagcgtaa
    38341 gaaaattaga taaacagttt aatattttaa atataaaatt tgtaaagctt tttgataaat
    38401 atgataatca agataatata aataaagaga ttttatttga tataaaagaa tcttcaaaaa
    38461 atatatacaa tgccactgaa agccaattca aaattagaga ttatataaaa aatataaatg
    38521 caggatttgc tctatatgaa agaagtgctc aagatttatt aactaaatta atgacccatg
    38581 aaaataaaat ctctcaaaat caaaaaatcc ttttagatga aaagtttacc ttagatgact
    38641 caataaaaaa tctctcaagt attattgaaa acttttctaa tgacctacaa gttaaactgg
    38701 atatgatgtt tgaaaattct ttagatattc aagataagtt agatgttatg tttaataact
    38761 cttttatgaa tgatgaagtt cctcttgata gtgaagaatt atttaaggat gatgttaata
    38821 atgtatttaa tccttttagt gaagaaattt atgagataga ggataaagaa ataaaggtca
    38881 taggtgagga tgagttaaat gaataataaa tatagaagaa ctgttaacag agaatttgaa
    38941 aagagtagct tttggccaac atttacagat ttattatcta ctgtattgat ggttgtaatt
    39001 cttatcttat ttagctcaga aagtatttca ggttctgttg aacaagattt agctaagaat
    39061 gtcaatgctt ctgttgaaga aacttttaaa aaaagtggaa tacctgtgaa ggtagataaa
    39121 tctaatgggc aagtaacttt tggtgaaaaa accatgtttg atgtagatag tgatgtttta
    39181 aaaccagagg ctaaagaaat gctaaaaatg tttgttccaa agtacataga gactatttat
    39241 aaagattatg gtgactatat atccaaaata gttatagaag gtcatacaga tgatgtggga
    39301 agttatatat acaacttaga tttatcgcaa agaagagcat atagcgttgc taaatttata
    39361 gtgggagatg aaataggtga ctataaatac aaagataaag tgactaagca tattattgca
    39421 ataggaaggt caaaagctga actcatcaaa aatggtgaca atagcgtgaa tagagatgca
    39481 tctagaagag tagaactaaa atacgaaata aatattaatc aaaataaata attaaatttt
    39541 tataaaaaaa aagaaggcag ttggtgtgag ctttaagcct tctttaagga aaaagtttat
    39601 ttatttttgt tgatacttaa catattatag tttttagaag cagtttgcaa tatattaaac
    39661 gtaaatggtc gtttaaaatg cataactgga tactactgat gtaaaatatt tcattttata
    39721 taatataaaa attatacagt atcaattttc tatattattg tactataatc tattatttaa
    39781 aatattatgt aaaaaaatat cataaaaacg catatcatgt tataattact agagtattat
    39841 gaatatggag gcgtagtttg tgatagaaat aagtataaaa aataaaaaaa attctaaaat
    39901 taaaactttg atacttttat tgatagtatc tatatcaatt tatttaactg gttgtactac
    39961 attagataat ggaaataatc aatcaaataa taatgattct ttgtctagta gtatatcaag
    40021 tgataagaat gtaaaaattc attttattga cactggaaat agtgatgcaa tattgattca
    40081 agatggtaaa acttttatat tgatagatgg gggagataat gatgatgagg gattaatggt
    40141 agattaccta aacaatcaag gtgtaaaaga tattaaatat cttatagcta cccattctca
    40201 tgcagaccat ttaggtggac ttgattctgt tgtcaaaaac tttaatatag aaaatgtttt
    40261 tgtatcgaat ggttcagcag aaacaaagag ttatagggac tttataaatg ctttagcaaa
    40321 taagggttta tccccaagtg taccgcttga aaataataag ttctatttag aagattctta
    40381 ttttgaagtt ctaaatacaa atgggggaga tactactaat gaacaatctc tagtccttgt
    40441 atatactaat gggaatgata aagttttatt tacaggtgat gctgaagaag gtaccgaaaa
    40501 agaaatactc cctaagcttg agaaagtaga ccttttaaaa gtagctcatc atggttctcg
    40561 tagtagttca tctcaagagt ttttagataa agtaaatcct gaatatgcgg ttcttttagt
    40621 aggcaagggt aattcatatg gtcatccaca tcaggagaca atgaataaat taaaaaaaat
    40681 gggagtaaaa gtacatagaa gtgatgagtg ttcagatata atatttgaat caacaggtga
    40741 tggagtattt acaagttgta aagatggaag ttataataaa ggcgttagag aagatggaaa
    40801 ctctggaaaa tcaaacagta atacaagtaa aaatgattct tttaaaaata aacaaaatac
    40861 atccaattca gaagaaatag tgtattttac tccaaaaggt aagagttatc actctacaaa
    40921 aaattgtagt gggctttcaa gaagtaaaaa aatattatca ggcacaattg cagaaagtaa
    40981 gaaaaatgac ccatgtgata tatgttatgg aaaataacaa aaaaacaacc aatttatcta
    41041 taaagcttct gaactttaaa tcatttaaaa aataaaataa atgcataaaa aaataagcta
    41101 taatcaatag ataacacatt ttatctatac gaatagctta tttttttaag tattttttaa
    41161 tagctattta ataactctaa atacaccagt tacaatacct acaatttcaa cttctgagtc
    41221 attgagcata attggttcca taaaatcatt ttctggctga agtcttatta aatttccttc
    41281 tttaaaaaac ctcttaactg tagcagattc accatttata agtgcaacta ctatctgaga
    41341 atttaaggct gtattttttt tgtctactac aacgtaatct tcatctaaaa ttcctgcatt
    41401 aatcatactt tcgcctttta ctcttaatac aaaattgtta ctgcccttta ctaaactggc
    41461 agggaatgga atgtattcct ctatgttttg ttgagctaaa atgggttctc cagctgttat
    41521 ttgacctact aaaggaagct ctattatttc ttgattagct ccagaaacat catttacttt
    41581 actacgttct aaaacttcaa tagctcttgg tttagtaggg tcctttctta tgtatcccag
    41641 tttttcaagt ttatttagat gagagtgcac agttgaagta gatcttaacc ctacagcagt
    41701 acatatttct cttacagcag gtggataacc ttttaatatg atttgagact ttataaattc
    41761 caatatcaag acttgctttt cagttagatc taaatacata acatcactca tttccaaaca
    41821 tattttgttt ttatttccat acactttata tttttaatta taacataatc catttatatc
    41881 tgcaaacatt tgttcctgat ttttaatcgt cctcaatcca ttcaaaattc ttgactatat
    41941 cacgttttac atttttctta tgagctgcat aaagctgagt agttgtgaca ttatcatggt
    42001 caagtaagtt ttgaacatca tatatagaaa atcctgtttg gattagagaa gttgcagccg
    42061 ttgctcttaa tttatgggga ctatatccat tgtctctagt agtatcaagt ggaatagatg
    42121 tatatttttt taccagtgtt cttatagcct ttgctgtaat tctcttattt tgaagagaca
    42181 aaaataaagc atctttttct tcatcattta atagttcatc tcttgttctt tcgttttgca
    42241 aataatcttt tattacatgt tcacaagtat gatttatagg cattaaaact tctttcccac
    42301 gttttctata tattttaaat tcacctcttg aaaaattaaa agaggagata ttgagttctc
    42361 taagctcatt taatctaagc ccgtatgtaa caaataatgc tagtatagct ttgtcacgta
    42421 atttagtttt tctccaatat accttttctt tctctgtaag cccttcacct gtttctactg
    42481 attcaagcat cttagcaact tcatctatct caaggcgctt aatagcatct ggctgaggtt
    42541 taggaagttt tattggattg aatccatcag ttatattatt atctatctga gagtttctgt
    42601 ataagaattt aaatagagta gagatggatg atttttttct tgctaaagct ctattgttat
    42661 tttcaaaaat caatgtgttt ttttctgtat ttttgtaata tctactgcaa taatcaccta
    42721 agaataaatt tatatctctt gattttattg tattaaaatc atcttctgta atatctttta
    42781 cacaatctgc atttgttaat tctttggttt caatcaaata tgaacaaaaa aaattaatat
    42841 cttctaaata agcaagtcgt gtagaaactg caacagaacc ttttaaatat ataaaataat
    42901 ccttcataaa tacaggaagt ttattttcca aaagtagaca tttttctatg agttcatttt
    42961 ctttgataac aatattatca ggtttatctg atttattatg tacttttata attttcttat
    43021 cattattcaa aattaaacct cctaaaacta aaatataaat cttttatatt attttttgat
    43081 atttatacca agtgagtata aatatttaat ttaatcattt tttacatttt taagagatta
    43141 gcagtgcttt agatgaaatt atcactaact attccctaaa tccacattta aagactagtt
    43201 gaatttaagt actctttttt atttctcaat atatttatag aaatatttta aaatatattg
    43261 agaaattttt tatgctctac taaaatcttt tttatataat atttttatat gtttctaacg
    43321 aaaccaaata ttagtaaaat atgtatttat ttaactaaag tttttaaatg ggctgactaa
    43381 gcttaaaata taggatatta tgagagttac tattgaaaaa ataaacccta ttgccataaa
    43441 gaaacttata aatatgttat acttaactat taaactggat atattcaagt tatcaaatcc
    43501 aaataagtat gtaattgaac ttattacaaa aataactata actataaagc tcagaccatt
    43561 taagctattt tttaaatcag cactactaag tgacatatgt gtagatatag aatacattaa
    43621 aaacataaat ataaaatact tcaatgaata tacactaggt gttaacaaca ttattcttat
    43681 aaaattggaa atatcaccta aaataatgtg tataaaccca tttatattta aattattaat
    43741 catacttaca tataacttta aatctatatt ttgagtcact ttcatataac tatctggcag
    43801 taatatctta aaaattaaaa taatcattat tgttccacct ataataggtg caattcctat
    43861 aaagaaattt cctatacttt gataaagatt atctttttta tagctatgac ttacatatcc
    43921 tagtatacca tcatttttac tttctattgg tctgaaaaac ttaactgaat ttattttatg
    43981 catgaaaatt aaacacatta tcaaatgact caattcatga acaaacgttc ctatagctcc
    44041 agttacaata attccagttt ttccaaaaga tgaaaatata aatttattat ttagattttc
    44101 tgtaatgcta aaaatcaatc caaatacaat aaatattcct atgaaacaaa aaatatttat
    44161 tacacttatt tttaaaattt cgattatata aatcataagt taagtcctca tgtaaaagta
    44221 tttaactact ctacttcata tccattacag cttaaaattt tacaagcatt ttctatatct
    44281 ttttctttta ctaagatata gtctgtatca taagtagaaa ttgcaaatat gcttattttg
    44341 ttgtctgcta acaaactact taacttagat aaaattccta caagtgaaaa gtctaaagga
    44401 cctagtatct taagtattct ccactccttt tctgacttga catcagaagg aatattatta
    44461 tttaaacata caacacttaa ttcatcatca gttctagtta tagagtaaaa cttctctgta
    44521 tctatccatg ttggtatttt actgtcatta tttaatctac atactgcata ctcttctacc
    44581 aataatttta atttcataat gtatatttcc tccaatctta tttgtttact taagattata
    44641 cattaaaagt tacataaaat aaaacatata aagtaaaaaa ggttcactat agtgtcctat
    44701 ttctatagcc aacctttaaa acttaattaa attctaataa agagatatat tatctaggtt
    44761 caattataag tttaatggct gttttcttat caccttcgat ttctatatca gtaaatgcgg
    44821 gaatgcaaac taaatccatt ccactaggtg caacaaaacc tcttgctatt gcaattgatt
    44881 ttatcgcttg atttagagct ccagctccta tagcttgtat ttctgcaacg cctcgttctc
    44941 ttagtactcc agccaaggct ccagctacag aattaggatt agattttgat gaaactttta
    45001 gtacctccat ttcaacatct ccttgttaat ttgttaaagt atccattacc taaagtacta
    45061 aatcataatt gccatttact aattacaatc atcatttaaa gtatactttt ataaaaatat
    45121 acttctataa tcgttttaag aaaaccttta ttttttttaa ccattttatt atgaaaaaac
    45181 tacaaatttc tttatattct ataagcattt tccaatattt ctaaattttt tatatctttg
    45241 agctataatt tcctctttat ccatatcttt gtaatgattt aatctttcta aaatataagc
    45301 ttttatttct tttgaaacag cttctacatc tttttgtgct cctccaagag gttcttttat
    45361 aatcttatct attattttta aatcatataa atcattactt gtaagcttca taacatcaca
    45421 agcttcttta gctttagatg aatctttaaa tagaatacta gaaagtcctt ctggagaaat
    45481 tacagaataa actgaatgtt ctaacataca tacatcattt cctactccga tacctaaagc
    45541 tcctccacta ccaccttcac caattacaaa agtgattact ggaacagaaa gtttactcat
    45601 ttcaagtaag tttcttgcaa tagcttctcc ttgtcctctt tcttctgctt ctagaccaca
    45661 aaaagctcct gatgtatcaa taaacgttat tataggtcta ttaaattttt cagcttgttt
    45721 cataagtctt aatgcttttc tgtatccttc tggatgaggc attccaaaat ttctttttat
    45781 attttctttt gtatctcttc ctttttggtg tccaactata gtaacattaa actttcctat
    45841 ctgaccaatt cctccaacca tagaagggtc atctttaaaa agcctatctc catgaagttc
    45901 taaaaaatta gaacaaatat gttctatgta ttccaatgtc gtaggtctct ttatatctct
    45961 acttaatgtt accttttcat atgctgatag atgtgaaaaa gcatcttcct taagcttttc
    46021 caatttctca ttaagtgaat ttattttatc acttaaatct atattatttg ccttagaaat
    46081 agttattaat tgtttaatat cattttctaa gacttttatt ttttcactat tattttcaat
    46141 caaaacagtt cctcctttat gccctatttc ttgtgcatag caagaatttg atataatact
    46201 tccttcattt ttcttctatc tactatcatg tcaataaaac ctttttcaag taaaaactca
    46261 gaagtttgaa atccttcagg aagtttttga tttattgttt gctctattac tcttggacct
    46321 gcaaaaccta tcaacgtatt tggctcagaa attataatat caccaagcat agcaaaacta
    46381 gcagttactc ctccagtagt agggtcagtt agaactgata tatatggcaa taatttttct
    46441 tcaagcttag aaagtgcttg agaagtcttt gccatctgca taagagatac cataccttct
    46501 tgcattctag ctcctcctga agcagaacaa ataattatag gtaaattatt ttcagcagca
    46561 tactctattg aataagttat tttttcccca acaatagaac ccatacttcc catcataaaa
    46621 tcaggattca ttacacaaat aactgtttta attccattta ttcttccata acctgtgaca
    46681 acagcttctg actcttttgt tttttcctta taagagtcta ctttttcttt gtatttagga
    46741 aaatttagtg gattttgaaa ttctacatca gaattaaact ccataaaagt tcctttatca
    46801 atcaataaat ttattctttt tcttgctctt aagccataat gtcttgaaca ttttggacat
    46861 acaaatgaat tttcttctat gtcctttcta aatacatgac tatcacaacc tttgcaatag
    46921 gtccaaaatt tatcatctac actattcttt ttaaagttgt catctaaaga aatcgtaaca
    46981 tacttagatt cttttgatga taaaaatttt tttatcataa tctatttact ccttataatg
    47041 tagcaaattc tttcttcata aagacatctt ctataaattt ggtatgatga gtatcttctc
    47101 taaactcctc acttgttaca agtgcctttt gaaattctac atttgtatta ataccttcta
    47161 caataatttc gtctagagct ctatatattc tacttataca ttcttctcta gtttcagccc
    47221 aacatattaa cttacctatc atagaatcat ataaaggtgg tatagtatat cctgcatata
    47281 caaaagtatc aaatctaaca ccaaaacctc caggtaaatt taatgattct atcttacctg
    47341 gtgatggagc aaaattcttt gatgaatctt ctgcatttat tctacattca atagcatgac
    47401 ctctaaaagt aatatcttct tgtttaaaag gaattttatc cccattagct atagatattt
    47461 gaagttttat aaggtcaaga tttgttacca tctctgtaac tggatgttca acttgtattc
    47521 ttgtattcat ctctataaaa taaaagtttt tatctttgtc aactataaac tcaatagtac
    47581 ctgcaccgat ataacctact ccttttacta tatctactgc aattttatga agtttttgtc
    47641 tttcttcatc tgaaaggtat ggacttaaag attcttctat tactttttga tttcgccttt
    47701 gcatagaaca atctctatca cctaaatgta ttgcatttga atgtttatct ccaaatactt
    47761 gtacttctat atgtctagga ttttctataa acttttccat atataaatca ctattagaaa
    47821 atgctgctag agcttctgaa cttgccatat caaaatttga aaaaagttct tcttcttttc
    47881 taacgattct catacctttt ccaccgcctc cacttgaggc ttttatcata acaggatatc
    47941 caatttctct tgcaacttct aaagcttctt ccttagtttt caaaacagat tctgaaccag
    48001 gaacaacagg gatattcaat tccatcatag tttctcttgc tctagattta tctcccatca
    48061 aaatcatttg ttctcttgtt ggacctataa aaataatatt attatcttca cattgctttg
    48121 caaattcagg attctctgat aaaaatccaa agcctggatg aatagcatca cactttaatt
    48181 taagagcaag atagattata ttttctatat tattataact cttacttata ttatttggtc
    48241 ctatacaaat agattcatca gctatatatc tatgaaaaca atctttatct atttcagaat
    48301 agatagcaac agtttttata cctagttctt tacatgttct gatgattcta actgctatat
    48361 cgcctctatt tgcaactagt atttttttta tcaacttaaa tacctcctac tacaatggtt
    48421 ttatcttaaa taaaggttga ttatattcta ctagttcttc attactaact aatacttcaa
    48481 ttatttcacc tttaatttca cttgttatct cattcataag cttcattgct tctaatatac
    48541 ataaagtgtc gccttcttca actacatcgc caactttaac aaagctatct gcatctggac
    48601 ttggagaatc atagaatgtt cccatcaaag gagctactac tactgataga ttctcattag
    48661 atgtgacagg tgtatcgttt acaactggct tttctaaaga aagatccact actgattctt
    48721 gttgtacact taaaacaggt gaacttgtag attgagcttt tttagatact tctaatctta
    48781 aatcgctact ttcaagtttt acatattcta agttagttga gtctatggcc tttaataatt
    48841 ccttaatttc attgatgttc attttgttac ccccttgtat tattacctgg tgctaatatt
    48901 atatcacaaa aaacaaattt ataaaagaaa aagtgctgac tagagaatca acacatcaat
    48961 atatctttta attttaaatt aacaaccagt aacttatatt tgttttaatt ttccattatt
    49021 aatataaatt ataagtataa aatgaataaa attcaatatt ttttgcaaaa tacaagagaa
    49081 tacaaattaa tacctcggga atttttaaga caaataccaa tattatgcaa tttagacttc
    49141 gctttctttc aaattagtat cattttcttt atttttacat aggatgtact ttaatttagc
    49201 tatcaaaaca ttgctatata ggttaaaagt tattagaatt gcaggaatta taaagtaaac
    49261 tctagcacct ataaaaccaa aaactactgt aataagtatt aatcttttat ttaaagtaaa
    49321 aaaaggtata ttaaaaatac ttttgtcgga tgtttctgga gtataagaat atataactcc
    49381 aaaaatcaaa gtaagcatac aaagtggaag tagtgtataa cttgaaatta ttcccagaaa
    49441 tcctatactt tcaaaatatt tgctagcact atttgtataa acaaacatgt atccatttaa
    49501 atatgcgcat atacatgata taatgccaaa agttccccct aaggattgag tgtaccaatt
    49561 aaaaaattta gattccatat acctcacctc ctaaaactgt atatataatg atatgcattt
    49621 aaatagtaaa atatatcttt atatgtttct gaataaaatt ttgttaattt cattaattta
    49681 tgtttaagaa atttgaagta tagtgtagta tatattaatg tagatgaagt tttatagtac
    49741 ttatttcata gtgcttaatc aagttatctt attatggatt caaaagttgt ttgtagggtt
    49801 ttatattttg ttgagctgaa aaatttatta taaatgaagg gatgttttcg ctttggtaga
    49861 tacattagaa tttggtctta aaattttatt ttttatatta tcaataattt ggatgggtaa
    49921 aataatgatt ttaagaactg ataagcaaat agtaatcaat cctttgctta ttggtatatc
    49981 tgcagtcctt gtgatgttgc atacctcaca gagtaacatt gaattttttg gattagatgt
    50041 ccaatatata agaatagttt tgtatataat atattcactg ataattttaa taggaatatg
    50101 ggctactaac agaagaaatg gaatttttta gataatctat ttctataaaa tttaaaggtt
    50161 gctagtaaca aagcactaat attagcgttc tgttactaac aacctttatt ttgattatac
    50221 acttaaattg aaaatagaat gattgaataa gttgacagat tattttacat tgacagtaat
    50281 tagaacttct tgagatgtat ttaaatcatt tttgtcgctt agtataactt ttaccactgc
    50341 ttgacctgtt ttattacctt taattatcat atcttcacat gaaagtacac tcttatcact
    50401 tacagataca ataaaattta aatcttttgg aaggttatca gtaacttccc agtatttata
    50461 ataactatca attttcttcg taattatttt tctcaaatca atactttcac cttttgctat
    50521 atcaacgtta tgatatttag agtccagttt atactgatta tcttttgtat caataaaatt
    50581 taaatcgcaa tttacatcca caccattatg agaaagagaa tttactacat cgtcatcaat
    50641 caaataatta ttggcaagat ttattgaatc catatctttt agacttaaag cttccttagg
    50701 aatctctttt atattattat tccaaaaaat aaaattgtct acattttcaa gatatgatat
    50761 accttttaaa tttgaaatgc tctcaccagt tgcataaaat tctccatcta aagcctttat
    50821 attgcttata gtcatctcat ctggatttat atatcttttt acaactgctc ttaaatttgc
    50881 atcaggaaaa atatctttaa gttgattttc gctcaaaacc ttatcatttg aatttattgg
    50941 acttaaagct gctgcagaaa taataaatgg tattaaatta gctaaattca tagtaccctc
    51001 ccacataaat tttttattat aataatttaa tttctatgag agggttctgt ttccttgtta
    51061 tatataccta ctttcgtaca ctttattaat ataaattaaa ataaatttct actattaaac
    51121 ttataaacat attactagtt acgtttttta gcttcacatc taaatattcg cataccttgt
    51181 gacataaatt tgtcttcata ctctgttgta acattatttt catactcact atttcctaaa
    51241 tcaagagaaa tattctttaa tagccaatta tttgcagcaa tttcatttaa actaaactcg
    51301 aataattttt cattatctgt tttaaagtga atttcgccat catcttccaa aaccctattg
    51361 tacatttcta aaaatccaga atgagtgagt cttcttttac tccatctatt tttaggccat
    51421 gggtcacaga aatttatata aattctcgat aattctttag cttcaaagta atccaaaata
    51481 ttgcttacat ctccccataa aaatagtata ttattcaaat tagaagcatc tgctttttca
    51541 acagccttta aaagaacttc ttccttaagt tccatggcaa tataatttat gtcagggttc
    51601 tgcttagcta aagttgttat aaacttacct tttccagtcc caaattcaac atgtattgga
    51661 ttatcatttc taaactttaa attccacttg ccttttaatt tgtctatatc gtctcttaaa
    51721 acatattttg tataacttaa aagcttttca tctgcacctt tttttcgtct tcttctcaca
    51781 ataattctcc ttacatataa aaaattagta aaatacattt ttattataca ttatctcacc
    51841 aaaaaataaa aagaactctc ttaaaataga aatttatttc tataaagaga gttctaaact
    51901 tactaaaaac ttaatcttag tggcaccctg aacaaccaga gcatcctcct ccaccttgat
    51961 ctttcatatt ttcaggaata actctaaatc caaatcctgt atcttctatt attatatctc
    52021 catactgact atattcatca gagctcatta caaattgtaa ttctccaact tcataagtta
    52081 agtcatcttc ttttttctca tctaaagcta atccaaaaga aggacctcca caaccaacac
    52141 ctgcaaagta tactcttata ttattaggtt tatcttgatt gtcttttaag atacttttta
    52201 aagtatcaat agctgtttct ggtaaagtaa ttttcatcaa atcattccct ttcaaatatt
    52261 ttattaaaac aatatctatt atatacccat acaaggtaca taatcaatta gtttttgcat
    52321 attttactaa aacttctacc taatattacc taaggcttta aaatatttta tataatattt
    52381 tattacctta aataaatacc ctatcataaa cttagtaaac aaataaaatt attattctaa
    52441 aaaatataat aattttattt gttgttttaa tattataaca catttgataa tgtccaattc
    52501 atatatgcaa aatttatata ctttaaaata tctaagaaat tattcaataa aaaaatacta
    52561 ttttttaaaa attatcatta ttgataaagc tctactattt atatttttta gtgtattcat
    52621 gtataataag taaaagcaca acggtatata ctgttgtgct tttttgtaat taataaacaa
    52681 tattttggtc tataacaatg aaaaatggct actttccata attgatttca tctgacataa
    52741 gcaaaaaggg tgtccagctg ggtcaatcat aactctccag tcatcagtaa attgctcctc
    52801 tgcgattgta gctccacaat gaattgcata ttgaactgct tcttctaaat cattaacagc
    52861 gaaatccata tgagccattt gctgttgaga ttcaggtttt tctggttcta ttatgcccca
    52921 agcctttgtt ttttgcaata taaagaaaaa attatatatt ttaatatttt ataattgttg
    52981 aaattgtgta ataaattcaa ctggatacat agtgcgtttt gaaatttctt ctaaagctaa
    53041 accttgtttt aaaagcctct ttatgacgct ttccatactt tctgaaattt ctataatatt
    53101 tttatcaaaa tcataaaacc taaaagttct ttgaccccat gggtattctt ttatataatg
    53161 caaaaattca atatttccta ttctatttat cttactttcc cattgtttga tgtcattaac
    53221 ctcaaaatac aactgaaagt tatttgattg ttgatatatt ggtaaatcat atccaattat
    53281 agctttataa ttactttgta atccaaatcc attttcaaat gatacatgtt ctcctaaatc
    53341 taatgtgatt ttttgctcca taacatcttc ataaaacttt tttgatttat ttatgtcttt
    53401 gacaattagc aatactcctc caaatttcat cttatcacta tcctttcttt gttataagta
    53461 ttataactta aaattttgca atttcactgt aaaaatcaga catattagct cggtattttt
    53521 gaggagttat tccacagaca attttaaaat ctttaataaa atgtggtata tcatagaatc
    53581 ctaattcatt acatatagac atcaatgaag ttttattatt gtttagaagt tttatagatt
    53641 tattaatacg taccaaacga gaaaatgact tcatactcaa ccctaggtac tgattaaaga
    53701 gtctgtttaa atgcctagaa ctataaaata cttttttaga aatttcttgt gaagatatat
    53761 ttccagagtt ttgaataatc aactgaattg ccaaaataaa ctcatatgag tattcaattt
    53821 taatattaga aatcaataat tcttccaact ttaaaatcaa tttatctata gataaagatt
    53881 cattaaatat ttttttaatt tctaaatcta atgaagtatt aattatagaa aatggaacaa
    53941 ctttatcaat aagttcactt tgctgtatac ctataagcgg gaaaaaacca gcaggttgaa
    54001 attctataat tagtataaca tcacatctat tagcaatatt tcctactgtt tttggtttag
    54061 tagttggacc aaataataga ctatgtaacc ctgtggcatc ataaaaaaac accaaagtta
    54121 cacttccatg aggaataatc gtgtaattat cagaaattat tgtttgattt ggaaacgata
    54181 tagtaaaatt cgatatccaa tttcttaatt gtatacaagg caagagataa acaaaattgt
    54241 cttcacaaac tataagtgac ctatttttat ttataaaatg aatactttct ttttttaaca
    54301 tatattatat cctgtcctat cgtgaatatt tattaaagta agaagaatcc atattatctc
    54361 tatatatcat taactgcttt taataataga gatagtatga atactcatta gatatttaat
    54421 aaacaaataa aattaaaata atcaataaaa aatatagtac ttttatctgt tattttaata
    54481 ttatagcaca tttatagtat ttaacttata tccactttac atatgtctaa tttatataat
    54541 taaaaatgct tatctcaaat acaataatta gtccttatac aattaaacca tctgaaactg
    54601 taatagtacg actactactt ttggctgctt ctggtgagtg agttaccata attatagttt
    54661 gtccattgtc tctgtttatt ttattcagta aatctattat ttctatccct gttttactat
    54721 ctaaatttcc agtaggctca tcagcaaata gaatctctgg ttttccaatt aaagctcgag
    54781 ctatagcaac acgttgttgc tgaccaccag ataactctcg tggtgtatgt ttacgtctat
    54841 cagttaaacc aactatatct aagatttcat ctaattgatt tttataatct tttaaatttt
    54901 taccatctaa taacaaagga agcattatat tttcctccac atttaaattt ggtattaagt
    54961 tataaaattg aaatacgaat cctatatttc tacgacgtat tatgctcatt ttctcatcat
    55021 taaaatgtga tatatcagct ccattcatat acacttttcc gctcgttgga gtatctaaac
    55081 cacctaaaat atataaaaga gtacttttgc cagaaccaga ttgacccatg atagaaacaa
    55141 attcaccttt cattacttgt aaagatacct cttttaacac tcgagttgtt gtatttccaa
    55201 ttttatattc tttgataata ttttttgctt ctacagctaa actattatgt gtaattttca
    55261 tattaacctc cataattatt caaacttaat ttcttctatc agtttcattt tcttcccttt
    55321 tataataggc actatcgaac ctattaaagt tactataatt cccaataacc caacaataat
    55381 aaatgtttta aaatctaaat ctggtttcat tgaaattttt ggtcctgcaa ctataaagat
    55441 agtttgaatc tcaagtatag atatcacaat accaataaca gctccaagta aacctgaagt
    55501 aaacccttca atcaatgtca cttttatatt ttgtttatta cttagtccta tagatttata
    55561 catagctata gaacgtcttt tttgaatata attaatcagt agattattaa taatacctac
    55621 tgtagcaaga agaaaaatga aataggtcat cttattcata ggagacaaaa aactacttat
    55681 agtatttaaa gaatcattat taaattcttc aactgtacga ctccaattat atgtatctcc
    55741 aaataaatat cttatctgaa tcataacagc atctggattg actgctgtat atactaaaaa
    55801 accataatta gttttatcaa aatcattaac tgcataatgt gatggtataa cagcttctac
    55861 atcatttgcg cgggatttaa aactacctac tattttataa gaaaaatcat acttatcatt
    55921 agatagagtt attgtatctc ctatagataa gcctactttt tttagagtat cttcattcaa
    55981 aataacagaa cgtttatcat taaaagcttc tattacttgt ttttttatct caaaatttgt
    56041 ataattgatt ccaaacatag agttatatag ttttatatta tctgtaccct ctagtcttga
    56101 taatgttaca ccattaccag aaatctcatt attcataaca taaagaggta atattttttt
    56161 aattccatcc atatgtctaa catcttcaat aaactcttca ttcatctttc catctgcaaa
    56221 accttgtaat tctgcgtcac gaaacacatc tgttatataa gttttgacaa agttaccaac
    56281 aacacttatt gcaataactg cagaaatact tataaatagt aaagtgatat tctgtattat
    56341 atttttgtta tttttcatat ttctagcagc taatttaccc tcattcccta aaatattttt
    56401 ataaacaaac tcaaaaacta tagacatgat atcagtaata agaggaatca acacaatagt
    56461 agctacaatt aatcccagta atgaaaatcc accagctaga tacaatgtat tttcagggga
    56521 tattcttgga agtaaaatag ataaaataaa cattatactt cctataaaaa gtatagaacg
    56581 atttgaaaca ttcttttctt ctactgttcc tagtacaata ttttttatcg gcaaatggct
    56641 agctttttta acaggtatat atgcactaaa tgaagaaacg attattgcta ctataacaga
    56701 tataatcact ccaatgggtg atattactac tggaattgat attccttgtt cgagagaatt
    56761 tcctaaccca tgaagcatta aatttaaaac aactacacca ataggaatag caattaatcc
    56821 tcctatactt ccgtataata tactttcaag catcaatata cgagttacag ttttttcatt
    56881 ggcaccaata cttctaaatg ttccaataaa aggaagacgt tctaatgtaa taaccttata
    56941 actgctgtat attataaata tactaagggt taatgcaaaa aaacttatta aaaagaaagg
    57001 cattgtcttt tgtctagcat ctgaaattat cttagtttca tttatagtat ttgataccat
    57061 atatttttca gtagaaagtt ctttggataa tttatttact agattttctg taatttcttc
    57121 ttctgactct ataagaactc ttgtatatcc actgccttta tttataattt ttgatagagt
    57181 ctctttgggt agcagtgcat ttacacctct tgtgttcctc aaaaatactg tatcataaga
    57241 tgcaatatca ctaacttgaa aagtataaga ctttccataa atctgcaaag taatagaatc
    57301 accttttttt attttatatt ttgatgtaaa gcgatttgga agaataattt tatcaccaga
    57361 aaaatcagta atactatcgc cattttctaa tcgtggcttg ttgattttat ttagttgact
    57421 taagtctgct gatataagac taaattcttc atagtatccc cctttattat aaatagcaga
    57481 gctttccaat acaccaacct ttgattttat agcatttaaa tcaggtatgt cttctaaatt
    57541 ggttaatata tctggatttt tactttggac agatatagtc gctgtaccat acataccttt
    57601 tgccattttt ctttgtgcac tttcataaga taatccaatt gagaatgaaa caaaaagtaa
    57661 aactgttgat aaaactatgg acaataacat aactgctgtt ctaatttttc gttctttaat
    57721 atttgtgaaa atatacttta atataatttt caaatttaca ccttctttcc ttatctaaga
    57781 tatttcaatc taatattttt atactttaat ctaaattaaa tctctaatag actcctccat
    57841 acttttatca ttctatttat aatattttta atcaaatcac cccttaaata aaaaagattg
    57901 ataaactact atataaatat aataatctat caaccttaat atatttttta tttgacctta
    57961 attaacctta attaaatagg aaaggtgata taaaatgagc tacctaatcc aggtatactt
    58021 tcaacagata tattccctcc atgaacttca ataatttgct tcgttattgc tagtcctaaa
    58081 ccagttcctt ctattttttg ttttgtattg cttcctctat aataacgatt aaacaaattt
    58141 gatgcttctt ctcttgacat cccttttcca ttatcagata taatgatttc aattctttca
    58201 tttaatgtta tatgtacaca aactttagta tttttatctc catatgtaaa agcattgaca
    58261 ataagattac taaaagctcg ttttaatagt gtacaatcaa aatcaaagtt aatattatct
    58321 atattactct taaattcaac tatatttgat tcatattctg gatagtttaa aatatcaatg
    58381 gataattctt tcaaaaatct tactaaatca taattatttt tatttaaagg gattattcca
    58441 ttttttaatt gataggttaa ttttaaatcg tttataagtg tatttgtata ttctatattc
    58501 tttaacatga ttgaagcata tttatatact ttttcaggtg aataattagt actactatct
    58561 gtaagaagct ctgcataccc ttttattggt gaaagtggag tttttaaatc atgagttata
    58621 tttgaaatcc actcttctct cataatatca gttttatttt gtatctcatc acttctatga
    58681 atttcttcat ttaaaatatt taaactatta tatatatcag caaaaacacc tttaatatta
    58741 actggaagat agcttcgttt tgaaatatcg ctaacagcag atgtaatatt tgatatgcac
    58801 tttgttaccc agtaaccata agcaattcca gaaaccaaaa ttattaaaaa tataatccct
    58861 atgattgaaa atacaattga cttaccacct ataaatttac ctccatcaaa aaacatattc
    58921 actttagata tatttaatgg aaaatatata atataaatat agtcattttt attattttta
    58981 attgtattaa agtatacagt tccattactt gaattatttt ggttagctaa tgctaataat
    59041 tcagaattag aataataatc tttatgctct tttggttcta aaaacccata aactctattt
    59101 ccactagaat ctaaaatttg caaccacaat tgattttctc gaagtttttc taatccagac
    59161 tgttttactt gtggcttatt atctataaat acgatttgtt cattaaagtt ttctgtaaat
    59221 tttttcggcc agtcactacg aataaattcc ccatttggtt tctgaatagt aataagtgat
    59281 aagaaaatac ctattactgt caggattaag caaataaaaa tcatgaaaaa aataatgtat
    59341 gaatgaaata ctgttttata actaggttta tgcatttaat caactctttt cttaaacttt
    59401 tattttgatt attgcttata taaaatagac aataattatt gatatgtaaa aatttattta
    59461 aaaatacaac tatctacata aattatattt atataattat atgttatcaa gctatctgtt
    59521 gtatttaata aatccttttg ataacatata aaagtaagat aaatttttcc attaaatacc
    59581 ttataattat acacaaaatc tctatatacg ttaaacagta tagagaaaat tttcatagaa
    59641 ccatctttat aggggatact ttataaaaga ataaaaaaat tataatatat aaaaacttca
    59701 taggagagta acaacatcag taaaaatatg aaaacactat ataaaaattc aaaaatatta
    59761 agaataatga aatacttgaa attgcttata tcaagaaatt ttatataata taaactggtc
    59821 aaatatgtta taatattaaa ttgtgacaag ttcatggagg tgtttatatg aaaaaacaaa
    59881 agtcgccaat tttacttgaa atgcttggac tattttttgg ttgtatatca atgagtattg
    59941 gtataaatat gtttttaaaa ccacatacaa ttgctcctgg aggacttagt ggtctatcat
    60001 tagtactaaa caaggttaca ggacttccag tatcagctat catgttaatt ataggtgtcc
    60061 cattagtaat acttgctttt agaattatgg gtacaaaaaa ttcattaaaa actttatttg
    60121 gaacagttgt attttcagct atagttcaat taacagaccc attatcaaaa ctaagattta
    60181 ctaatgactt attattgtct tctattgcag gaggaatcct agttggtata ggtttaggaa
    60241 taatgtttaa atcagatgct tctactggag gaacagactt aattgcactc atacttagta
    60301 agaaattccc aggaataaaa gctacaaaat tcatgtcatg cctagatgga atggttgtta
    60361 tatcttctgg tatagtaaat cgtagtttag aaactgctct ttactctggt atagcacttt
    60421 gtgtattaat aaaaatagca gatatgataa tggaaggatt tgaccattca aaagcatttt
    60481 ttattatctc tgatgagcct gaaagtttaa gacaagctat aactgaagaa cttgatagag
    60541 gtcttactat tcttgatggt aaaggtggat acactagaga aaataaagaa gttctattag
    60601 tcgtagtttc taaaaaacaa gaactttatc taaagagatt agttaaaaga actgacccta
    60661 ctgcatttgt tattgttaca gatgtacatg aggttcttgg agaaggattt
//
LOCUS       DAJMZY010000009        59623 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.009, whole genome shotgun sequence.
ACCESSION   DAJMZY010000009 DAJMZY010000000
VERSION     DAJMZY010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 59623)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59623)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59623
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.009"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            58..1878
                     /locus_tag="OE968_000550"
     CDS             58..1878
                     /locus_tag="OE968_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HCP7217867.1"
                     /translation="MTLKYKCYDMPLDTTLNYNQSTESYEGTINYNKDPEYLNVWELQ
                     GITINSKNNPKTLNKQELEKMGLNLKDYNVTQECIIEDITSRKDVNKYLRKTSAPITE
                     LTGSDRYETAVKISKEGWKNGSDKVVIINGDVSIDGIISTPLATTYNAPILLVEKNNV
                     PNSVKSELKRLNPRDVIIIGDENAISKTTANQIKSTVNASQTRLKGSNRYETSLLIAK
                     EIDKNHDVEKVYITNANGGEVDALTIAAKAGQDKQPIILTDKNSITDNTYKWLKSEDL
                     QNAYFIGGPQMISTNVINKVNDITKDNVTNNRVYGADRHETNANVIKKFYTDDELEAV
                     LVAKSDVLVDALAAGPLAANLKSPILITPKTYVSAYHKENLEAKSANKVYKIGGGLTS
                     KVMNSIASSLSKHNTTPTEPGNSGGKTVMIDPGHGGSDTGTTGKPLGGIKEKDYTLNT
                     SLATTEYLRSKGFNVIMTRDTDKTLSLGNRTALSNSLRPDLFTSIHYNASDTTGNGVE
                     VFYKLKDKDGGTTKTVATNILNRILEKFNLKNRGAKTRTLSTDPTKDYLYVLRNNDMP
                     AVLVECAFLDNEKDMSLLNTSNKVKEMGTQIGKGIEDSLK"
     gene            2386..4398
                     /locus_tag="OE968_000551"
     CDS             2386..4398
                     /locus_tag="OE968_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HCP7217868.1"
                     /translation="MRRNTKLLTTGILSMAIVAPTMAFATESNAMENNADLNINLEKK
                     SIVLGSKSKVSVKFKEKPDADSITLKYKCYDMPLDTTLNYNQSTGAYEGTINYNQDPE
                     YLNVWELQGITINSKNNPKTLNRQDLEKLGLNLKDYNVTQECIIEDITSRKDVNKYLR
                     KTSSPITELTGSDRYETAVKISKEGWKNGSDKVVIINGDVSIDGIISTPLATTYNAPI
                     LLVEKNNVPNSVKSELKRLNPKDIIIIGDENAISKTTANQIKSTVNASQTRLNGSNRY
                     ETSLLIAKEIDKNHDVEKIYITNANGGEVDALTIAAKAGQDKQPIILTDKDSITDNTY
                     KWLKSEDLQNAYFIGGPQMISTNVINKVNGITKDSVTNNRVYGADRHETNANVIKKFY
                     TDDELEAVLVAKSDVLVDALAAGPLAANLKSPILITPKTYVSAYHKDNLEAKSANKVY
                     KIGGGLTSKVMSSIASSLSKHNTTPTEPGNSGGKTVMIDPGHGGSAPGNSSGGMIEKD
                     YNLNTSLATTEYLRSKGFNVIMTRDTDKTLSLGNRTALSNSLKPDLFTSIHYNGSTNK
                     QGHGVEVFYKLKDKNGGTTKTVATNILNRILEKFKLTNRGIKTRVLPSDSTKDYLYVL
                     RSNDMPAVLVECAFLDNENDMSLINSSAKVKEMGTQIGKGIEDSLK"
     gene            4640..6553
                     /locus_tag="OE968_000552"
     CDS             4640..6553
                     /locus_tag="OE968_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7217869.1"
                     /translation="MEYLFEKSSLKEYGNEALDKYRELLDKTGNNSRCILLLVPNNNT
                     KIRYERALRLNYSEELKVTTYISFVKKELVKYWPLIIEKCDGISTKVVSPTFISNSLS
                     EYLIVQKVKEKRIQEGYFEDITGTNKSIANSIMTNINKSAFNLIDFDFIGEKIYSSKK
                     NKDSIYRFSYTQMDEIISYYINSLLSNSILDNALSIYLYNQYLLNDDFYLKNLFTEVR
                     YIIVDSLESSSNAEVDFITEALDNTLQSYIYFDYSRDYSVFNNVDIDYINEKIISKIK
                     PKEENIKKKEIRIEDLYLLPANIELNQSSQLYNEMLDLISEKVISLIEEDVSPRDIAI
                     ISPINNSILEHQIRDSLIEKNIDVFSTKKDKKAVDYPYGNALVVATCIFYGYLDFIKD
                     DEYLSFLETLLEINRIKAFKIFNETRHLSIDNIDEHSQYRDILQYIEEKKKSDIKIHE
                     FLTQFYIDKMLNLKEGKKNVGLCKKIIAESESFSESLSLLGMKKEKIFVEALKSTIND
                     YYSVVDIEELKSKDKIVITTPYSYISSNIDRSIQIWVDIGSNAWNMKIEKDISNLIVL
                     RKSFEEKKIYTNEMEEYYKKYYLYNTVYNLLLNAKKIYAFKSEYAINGYIQESILYSI
                     LLKISHKGDKNYD"
     gene            6546..8765
                     /locus_tag="OE968_000553"
     CDS             6546..8765
                     /locus_tag="OE968_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HCP7217870.1"
                     /translation="MININYREDQIPIINYDNGTMAVPAVPGAGKTFIITNLVAKLLL
                     EQKHKSGKILILTYMNSAVNNFKGRIRKILEENKIDDTNSYEVMTIHSLAVKIIKEKP
                     EVVMLSEDFNIADDLQKSIILNECISRFRFEGGERAFRWFLKEQKDERWKEITLEAWE
                     RGFFEFAGNAISELKYKGISPDKLEEILSRGHKGMLKIILPIYKLYDRKLKQNGLLDY
                     DDILILAEKTLSLDEGLRKKFQTRYKYIFEDECQDSNEIQGNIIKIISSENKNLVRVG
                     DINQSITGTFSSSDPKFFKEFINSADFCYRMDMSNRSSKDILDLANTLVKYVTKEFRQ
                     EECRHALEDMQIKTVPNGMGYKENPNPEHYNINVKWYESWKIEIEQTARYVKGIKNKY
                     PDKSIGILVPFNEQVTQVAKELRENNLTFEELGPNSLNKRKVINNIAYIIDFMLHCDD
                     VEKLIVVLNKVFIDTDNEEEIKYFLEELKNYSTEEIIYNFEFSKLDNDLIEFKEESDI
                     YLSFKRGIDIIKQILEYPIIRLDLLVLFIGKKLSLEKEDKAVLDYISFYIKYLVSENI
                     NMDLEDVYNLLFDVKNRVFNHIIDVVYEINGYEPEPGSITLCNYHKSKGMEWDCVFLL
                     GLVEYNFPDNINQKFQSDKWYLKEKYKNPMAIIKSEVEAILKGSISTDYAHKTKIDSI
                     NEKIRLLYVGITRAKEMLVLSGSAYRDESDIGNKRKEQKPCIYLSRLNQHIIEKRSN"
     gene            8874..9704
                     /locus_tag="OE968_000554"
     CDS             8874..9704
                     /locus_tag="OE968_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
                     /protein_id="HCP7217871.1"
                     /translation="MNDKLKYFSYSQNSINTYKSCPLKFKYKYIDRINWKNDDVGSRE
                     YYETLKTGRDFHLICERYFSNIPLGIYFNEDDKNSKKFLKWMENIKKVVPIEKGKTYL
                     PEYEVRMTLNGDIIQAKYDLVVIGNNNIEIWDWKTESKKIDYKHVENRIQTIVYMFLA
                     KEVIPKVLKMDINVKDINMRYYQPEFDDLPITILYDEEKHEANRNKIQNYISMIKNTN
                     YEEHTYEDNLYNDIEKVYNKEERMCYRNKKHCKYCEFNKLCNGKEIDYSILEAEIYGT
                     "
     gene            9694..13161
                     /gene="addB"
                     /locus_tag="OE968_000555"
     CDS             9694..13161
                     /gene="addB"
                     /locus_tag="OE968_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddB"
                     /protein_id="HCP7217872.1"
                     /translation="MGLRFVLGRSGSGKSTYILDEIKKEAQKNETTSIILLVPEQYTF
                     EAENRVSKLFLGKEKDKYLRVRVLSFKTLSNIVFSQVGGLTDVNINSSGKAMMVYRAI
                     EDVSEELNVFSKSKSQSGFVSSITDMISEMKQYNISPEMLENISGELDNETLSLKLKD
                     ISKIYNSFEGKLHENYVDAQDMLTSLASKIELSSYLDGACVYIDEFTGFTPNQYNVIK
                     SILNKSKSVNISLTVDDINYIGYSKSDMFSRTKFTYSKLTQLCNEEGIKILPQVNLNT
                     GVIKRFEKVKELQHLERFYNAYPYKIYSNQTENIKIKEFNNLYSEVEEIAREIVHLVR
                     DKNVRYRDITIATRDLNRYDFLVHSIFNEYNIPNFIDKKREAKSNPIVILIISALEMK
                     NRRYGYETMFRYLKSGLIGIDNDDINLLENYVLANGIKGKKWFDEKWDYRITQSLSGQ
                     ESEFELELKEKINEIKNRVLEPIVILQEKLRGKNRVKEICRYIYEFLLDINMPETIES
                     LIINFKDKGELDVANQYSQVWDIVVDILDQMVELMGDEIISLEKFIKLITLGFDEYEL
                     GLVPPSIDQVLVSSVDRMKNPDTKYLYLVGTTDGVFPLITKDSGILSDNDRESLGNKG
                     IEVDIDSKTRSFEEQFLVYKALTSTSKNLTITYPISDHEGKTLRPSIIISRLKKIFPN
                     IENKSYLVEENKSTDKDILKKITVKSPTFNELINVIKNYDSDGYNTEEINSIWLDIYR
                     YYLKDEIYSSITKKVIKGLSYTNQVHKIEEKKIRSLYKSNSLSISRLEKYAECPFAYF
                     IQYGLKAKKRKEYSFTPPDLGTFIHNILDRFSKELLQDNLTWRDIDEKYIELKIGIIV
                     DEIILKIPGYILNSSERYKYLAYRLKNMLTTAITIISQQIKQGSFEPIDYEVKFGNNG
                     KYPPIKMVLENGQEVSLIGQIDRVDEFEEGENKYIRIIDYKSGNKSISLTEIYYGLQL
                     QLLVYLDAILESAKDEDININPAAILYCRINNPIAKFNEDKDDEEIQEAILKELRMKG
                     LVVKDSHIVKEMDKSLIDGERKNSLVIPVGLTKDGNVGKSTSAISYEDFKLLRKYVRH
                     AIKDLCEEMLSGEIRIAPYKHKDGTSCDFCDYSAICQFDSTIKDNKYKNLNNKSNEEI
                     IKMMKGDVN"
     gene            13161..16988
                     /gene="addA"
                     /locus_tag="OE968_000556"
     CDS             13161..16988
                     /gene="addA"
                     /locus_tag="OE968_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HCP7217873.1"
                     /translation="MSSPKWTKEQLEVIESRECNLLVAAAAGSGKTAVLVERIIQMIT
                     SRENPIDIDKLLVVTFTNAAASEMRERIGDAIGKALDENPENKHLQNQLVLLNKSSIT
                     TIHSFCLDVIKSNFHRINLDPNFRIGDQTECAILKQEAIEEVFEDLYEERDEGFLNLV
                     ESYAERGGDKEVQDIILGIYSFAMASPEPKKWLIDSAERFNIDENFDFSQSIWARAIL
                     DTVKIEINGLCLNMERALKEVESIEELETFAEKLSVEYKKIADISQACNKSWDEAYKK
                     MASMSFENYVKGVKRISKDAPSYIKESKEKAKTIRDKTKKSLESIVSATFNKDNDSIR
                     EEIKYLYNIVKPISSVVLRFEEEYSNKKREKGIIDFNDIEHFALNILTDVDEKGNIVP
                     SDIAVGYRNKFYEIFIDEYQDSNLVQEVLLKAVANTETPNRFMVGDVKQSIYRFRQAK
                     PELFLQKYNNYNDKKGSSHRKIMLYKNFRSREEVVDAVNYIFENIMNENIGEIEYTEK
                     ERLNLGANFNVDTDEKSIIGGATEIHLIQKDNKLDDDIINDKDDRINNKENEIEEEEK
                     LDNIQLEARMVGNIIKDLMKVNEDGKIQKVYDKGIDGYRPVEFRDIVILLRATSAWAP
                     VFADELMNMDIPTYADVGVGYFDTIEIKTILSLLQIIDNPMQDIPLISVLKSPIFGFT
                     PEDLIDIRVQSKDKIFYEVLKSTAEYDGFTDSQNENESEFIPSEECINKSKDFLIKLK
                     EFKEKSMYMSTDEFIWYLYTRTGYYAYVGALPGGSQRQANLKVLFERAKQFEETSLKG
                     IFNFVNFIEKLKKSSSDMGSAKTLGENANVVRIMSIHKSKGLEFPVVICSAMGKNFNT
                     QDFKKSILYHHNLGYGPQFVDYERRISFPSIAKEALKSKINIENLSEEMRVLYVAFTR
                     AKEKLIITGSTRNIQDSIKRWSNGIESLDTISQYEILKGKNFLDWIMPCVLRHRDLSN
                     LLEEVGLDAVFNVEHNSKWYGKLWNKSDILVEKKSDEEKESIEEILEKIDVDNPDSDY
                     YSEIEEKLNYIYPYEFSTRKPATISVTEIKKIQNNYEEELINTIFEQKVILKKPLFIQ
                     NEEEREKISGTERGTIVHLVMEVLDLKNVSSVNDIKSQIRGFVSKGIITEKQASIVNP
                     YKIYKFFASNIGKRMLNAEIINREKSIYAQVNMKDIYIYEKLINNDDKKLYDNESVML
                     RGIVDAYFEEDNQIVLVDYKTDFVNEENINQIIEKYKKQLDLYADIIETLTGKSVKEK
                     CIYLFGVDEAVCY"
     gene            17034..18245
                     /locus_tag="OE968_000557"
     CDS             17034..18245
                     /locus_tag="OE968_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HCP7217874.1"
                     /translation="MRFIHTSDWHLGKSLEGHSRIEEQAKFCEEFIKIVESNEIDMVI
                     IAGDVYDTSNPPAQAEKLFYQTVSRLANNGQRCVLIISGNHDNPERLSAITPLAHEQG
                     ILIYGYPLSATIEAKYKGFEITYATQGCTKLNINGENIVVATLPYPSEKRLNEVFSSE
                     DEFEKQKNYSEKVGDIFRSLEENFRSDTINIAVSHIFVIGGESTESERPIQLGGSFLV
                     ERKDLPEKAQYTALGHLHKQQKASERLNAYYSGSPLQYSKDERAYTKGAYIVDIKAGE
                     KPIIEDVYFNNYKPIEVFKCNGIEEALDICEQNQDREIWSYFEINTDEIISQNEIKKM
                     KELLKDIIEIKPIITSCYEQESVDIKEKSMAELFREFYSFSKGVEPKGELMDLFLDII
                     SEEGESADETN"
     gene            18232..21759
                     /locus_tag="OE968_000558"
     CDS             18232..21759
                     /locus_tag="OE968_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HCP7217875.1"
                     /translation="MRPIRLELTGLNSYIDKQVIDFEKLIERGLFGIFGTTGSGKSTI
                     LDAITIAMYGNISRNTKEYINSVCDKAIISYEFEIGSKNTRRRYIVDRTIARSKTGTK
                     TSNARLIEVLNDNTQNVLADKVVEVNEKVAQVVGLTANDFTRSVVLPQDKFNEFLRLS
                     RADRRDMLERIFNLEKYGRSLGEKVKKRKNIQLQNLKDLKSKLSQYDGITEEVYNNIN
                     QELIELKNLEKDKNNALDLAQKSYEESKTVYEEQLKLEKNELRKNELDLKNSEIKEKI
                     ALVENDSNAKKVDPYISSVQNLEKKIDEDSFAVSNLEKKLAILNQELEVTKNRYEKIN
                     KIKNEEIPKLSEEKIRLQQAIKLEEELVLLDRELKELKESGINLNKTKVELEKVKQVS
                     ESRKDAVTKSIKEVEGKIDKVNISAELKQKIFLAYEYEKDYNNVLEEKNQKLNKLEEI
                     LKETENINLKVRYIDKDKNDVNRNLENLSLHLDVLLKKCPGKSADLLLKSEYVTELRN
                     KANNTKENEIKKSSIQDELKIILESKFNTEREVNLLNEKLENNRKNRDDLEKELEELK
                     YLNLASELRRELKENMPCPVCGSKHHENHDITKYDENISFVKEKLEKLEKEKISIRNN
                     IEELNAKVSGYLSIEKMKTKELEDVKGKLGGIPSSQLLKKLDEEQRKLALLKSNIQEW
                     EKEKESTENKVTLAKEEKNKIEKEELKIRESLNNYKKLTRDLNIEIEGLENKCKKLKQ
                     EYLGLKTITKVSNLLSKVKEIRENEKELELLSTGHSNLLKNRDSLDIKIRENESKLHE
                     IEIELIKARELYVEKKLSRDNKYKEVISITKGDLAKNLLHNVEENICKILEQEESSKK
                     KLEEQRLEYEKNIAEKHNIDGRLKTAKEQYKDQKSTLNKLLAENKFESIYAVKRALLD
                     TDAVKKLIEEILEHEEEQKLLSFKIKSSKEKLNGRSIKKEYFEQLKDEIYNLKVEIGN
                     ISKDIGANQNQLITLKDSLDKINDFNKQLKVVEHNVDLLEELDKCVQGNKFVEYVSTN
                     QLKYIALEASKRLDGITKGRYALEIDSTLNFVMRDNFNGGERRSIDTLSGGETFLTSL
                     SLALALSSQIQLKGSAPLEFFFLDEGFGSLDSELLEIVIESLERLHSNNLSVGIISHV
                     EELKNRVPVKLLVSSSEAGIGSKVKIEYS"
     gene            21890..23143
                     /locus_tag="OE968_000559"
     CDS             21890..23143
                     /locus_tag="OE968_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HCP7217876.1"
                     /translation="MLESPNNLIQIIFLIVLLIGSAFFSASETALMSLSKIRIRYMQD
                     EGVKGAKLVSSLIENPNKLLSSILVGNNVVNIAATSISTSLFIGLMGEKGVALATAVM
                     TVLVLIFGEITPKTIAANNSEKVSLLVSKPIKAIIFILRPIVWIFNIITNIIFKLFGI
                     TNKGAKSFITEEELKTMVNVSHEEGVLEMEEREIINNVFEFGDMQAKNAMVQRIDMVA
                     IDMEDSYDEIIQVFKTEKLSRMPVYEETIDDIVGILNIKDIIFLSDEEIESFDIKNYM
                     REPFFTYEFKKITQLLEEMKLEKSQMAIVVDEYGGTSGLLTIEDLVEVIVGDIEDEYD
                     EEEDEIQVIKEDEYIVDGSTKIGDVNELIGVNLESEEFDSIGGFIIGHLSRLPEENEV
                     IEVDNIRFCIESIEKNRIKKIRIYT"
     gene            23292..24344
                     /gene="ytvI"
                     /locus_tag="OE968_000560"
     CDS             23292..24344
                     /gene="ytvI"
                     /locus_tag="OE968_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation integral membrane protein YtvI"
                     /protein_id="HCP7217877.1"
                     /translation="MSILENNFLYKLKNNTIFFCIYTLLFIFIYKAFPYIAPFFLGAI
                     IALMINPISQKLENKFHINKGISTLVLSFLAVAIVSTVTTIIVINSMKELMGFLNNIS
                     ANPEDISNTIMYFLNKINDFMKSFQEIANFDVEQLVNKFSGEVMQITKNLLTSILGLA
                     TSIPYIIIFIITLFIATYFIAKDLDKIENSFYNMFTVDVRKKVKNVKKEAGLSLVGYI
                     RAYTILMAITFFAIWGSFALFGLKYGLIVGFVGALMDLIPFLGIITIYLPVIVYYFLI
                     KNYFIAISMTVIFFVLSLIREILEPKLVSVNVGLNPLATLAAIFIGIQVKGIIGVIFC
                     LGLVCMHDILKKVDIF"
     gene            24434..25660
                     /gene="pepT"
                     /locus_tag="OE968_000561"
     CDS             24434..25660
                     /gene="pepT"
                     /locus_tag="OE968_000561"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HCP7217878.1"
                     /translation="MKQKVVERFLKYVSFDTTSNSQCENCPSSEGQRVLAKYIVEELK
                     TMGVDDVSLDENSYIMATLKGNTDGVDTIGFISHLDTIEDVSGKDIKPKIIENYDGKD
                     IVLNEALNVITYVKDSPELEEFKGDDLIVTDGTTLLGSDDKAGIAEIVTAIEYLINHP
                     EIKHGDIKIGFTPDEEIGRGADLFDVEKFGAKYAYTLDGGIVGELECENFNAANATIT
                     IHGRNVHPGSAKNKMVNAIHIAAEISEMFPADERPETTEGYEGFWHLNSIGGNVENVS
                     MAYIIRDHCKEKFENRKSIMIENIEKINKKYDNRVELDLKDSYYNMKEKIEPVMFIVD
                     IAKEAMEELGIKPRLVPVRGGTDGARLSFNGLPCPNIFTGGLNFHGKNECIPVSSMEK
                     ATKLIVRIAEKYAERV"
     gene            25867..26919
                     /locus_tag="OE968_000562"
     CDS             25867..26919
                     /locus_tag="OE968_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp18"
                     /protein_id="HCP7217879.1"
                     /translation="MKIKSKKIIAFALSLGIMLPSCVYADNISKNQNAQVDMNNYLQG
                     RKSPKEEKLIGEDRFDTAIKISQSGWNNGSERVFLVNSNSLPDALASTPLASKLDAPI
                     LLTNKNSIPYNVTEEIKRLNPAEVILIGSEGAISSSVKESLEDMEVLVSRIGGADREE
                     TSLLLTRQLDDTGDLGVSKVAVVNGYNGLADATSISSPAASDNTAIIYTGKDSIRSEA
                     KNFITQNSTKTYIVGGEYSISKKLEGQLVNSERLAGTDRKDTNAKVLEKFYGKSSKVN
                     NMYFAKDGSGREADLVDGLAAGVLASKTKSPVVLASGSLSSAQKSFIKKVKADKFVQV
                     GGGKNSKPYAEALALQ"
     gene            complement(27337..27906)
                     /gene="yfcE"
                     /locus_tag="OE968_000563"
     CDS             complement(27337..27906)
                     /gene="yfcE"
                     /locus_tag="OE968_000563"
                     /EC_number="3.1.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphodiesterase"
                     /protein_id="HCP7217880.1"
                     /translation="MKIGIMSDTHGSLLYFEKALNVLSDCDVLLHGGDVLYHGPRNDI
                     PEGYNPKKFIETLNKLENIVIVKGNCDADVDQMVIEHPIQSPYVMSQFGEIRIILNHG
                     YIESEEEIIDKAKKMGGDILVLGHTHVKKLYMDDNLIVINPGSTSIPKDGSHSVAIID
                     IIKTDDEDELELDINLIDINTGNIININD"
     gene            complement(27931..28731)
                     /locus_tag="OE968_000564"
     CDS             complement(27931..28731)
                     /locus_tag="OE968_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(+)/NADH kinase"
                     /protein_id="HCP7217881.1"
                     /translation="MKRIITINTNQLNKSLETKELLTRKLINAGFEVYSDIYPDTELI
                     ISIGGDGSFLRTVRDFDFPEIPIMGINTGHLGFFPDILPDKIDSFIEAYTKKDYIIQE
                     MSLLNAEVYTTTSGSNMLAVNEVVIRGDKSRTIHLNLSLDNKHIQNFSGDGMIISTST
                     GSTAYNYSAGGSIVDINLELMQITPLHPINTNAYRCFTSSIICSNESVIKIAPEYRFE
                     DSVLIVVDGVEHRFRQIENIKVSISDAKIKLLRMSNYEFWHRVSEKFL"
     gene            28866..29726
                     /locus_tag="OE968_000565"
     CDS             28866..29726
                     /locus_tag="OE968_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCP7217882.1"
                     /translation="MFSIRNITKKLGKFKLNNINLELKEGDIVGIIGPNGSGKTTLIK
                     IIMGIIDADEGEIELCNETIENSPISFKNNIGFVYDSLQFYPHLKVKEFRKIVSLFYK
                     NFDRERFDEYLNKFDIEENMHIENLSKGQSEKLMLSSALSHNAKLLILDEPTAGIDPI
                     VRTEIMQYLQDFVKNGSSSVIISTHNTDNLIKIADYLVFINRGNQIFTVKKELIEQEY
                     KIIRANKAELEAIKESIVGVKEYKYYNEALVKVGDSLKVKSLLIEIDKHKVKNPTIEE
                     LMYYYVNEVR"
     gene            29726..30412
                     /locus_tag="OE968_000566"
     CDS             29726..30412
                     /locus_tag="OE968_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 transporter permease"
                     /protein_id="HCP7217883.1"
                     /translation="MFNLIRKDLIIGISSDGIRNLKYILLFFVFYFFLNSISYYTVSI
                     VVSYLIFINTFECDYENDSRIFIRSMPVSIEDIVYSKYLLGVGLIISVTIIVSLLSKL
                     TSLVFFRNMVLNDVFFSVNIFLAILTILLPLIFKFGYGKMKVCGFIVSILIYFVYGSL
                     LKMISMIVYQVKHFNYSKVGGVYLSNYVTDIANTKYINLYSMTFLTIIIFIISMYFSI
                     KISKKNKFNY"
     gene            30464..31006
                     /locus_tag="OE968_000567"
     CDS             30464..31006
                     /locus_tag="OE968_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7217884.1"
                     /translation="MKKFIKVSFFILGIFTLFIAINKLVYRDMVSVKDYEINHLEEIV
                     FDFDSRRSRDVGTIVRFKISNNSKYSYKLNSAKMKFENCVENKKGMNKCSAYVNVDLF
                     NEKNSITERTLKYGIKPNNQGYVDFVIPKGLNFDYRYFNESGMSVEYKGEYIVNIPMA
                     KGLYLVVGKNNDTWNANIME"
     gene            31085..31552
                     /locus_tag="OE968_000568"
     CDS             31085..31552
                     /locus_tag="OE968_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaK/EbsC family protein"
                     /protein_id="HCP7217885.1"
                     /translation="MSISNVREYFKQFGKEDSILEFEQSSATVELAAEAAGVIPARIA
                     KTLSFKIGDDAILIVTAGDAKIDNKKYKAEFNCKAKMLTPEEVLEFTGHAIGGVCPFG
                     LKNSIKVYLDDSMKRFDTVFPACGSSNSAIELTCEEMEKFSKCEKWVDVCKNW"
     gene            32261..33397
                     /locus_tag="OE968_000569"
     CDS             32261..33397
                     /locus_tag="OE968_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase"
                     /protein_id="HCP7217886.1"
                     /translation="MDLNSKKYQMLKELYVSFAENEVKPLATELDEEERFPYETVEKM
                     AKAGMMGIPYPKEYGGEGGDTVGYIMAVEELSRVCGTTGVILSAHTSLGSWPIYQYGN
                     EEQKQKFLRPLASGEKLGAFGLTEPNAGTDASGQQTTAVLDGDEYILNGSKIFITNAI
                     AGDIYVVMAMTDKSKGNKGISAFIVEKGTPGFSFGVKEKKMGIRGSATSELIFEDCRI
                     PKENLLGKEGQGFKIAMSTLDGGRIGIAAQALGLAQGALDETVKYVKERVQFGRPLSK
                     FQNTQFQLADMEVKVQAARHLVYQAAINKDLGKPYGVEAAMAKLFAAETAMEVTTKAV
                     QLHGGYGYTRDYPVERMMRDAKITEIYEGTSEVQRMVISGKLLK"
     gene            33456..34238
                     /locus_tag="OE968_000570"
     CDS             33456..34238
                     /locus_tag="OE968_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009524639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HCP7217887.1"
                     /translation="MNIVVCIKQVPDTTEVKLDPNTGTLIRDGVPSIINPDDKAGLEE
                     AIKLKEEMGAHVTVITMGPPQADMALKEALAMGADRGILLTDRAFAGADTWATSSALA
                     GALKNIDFDIIIAGRQAIDGDTAQVGPQIAEHLNLPSITYAEEIKTEGEYVLVKRQFE
                     DCCHDLKVKMPCLITTLKDMNTPRYMKVGRIYDAFENDVVETWTVKDIEVDPSNLGLK
                     GSPTSVFKSFTKSVKPAGTIYNEDAKTSAGIIIDKLKEKYII"
     gene            34257..35267
                     /locus_tag="OE968_000571"
     CDS             34257..35267
                     /locus_tag="OE968_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HCP7217888.1"
                     /translation="MGNVLVVIEQRENVIQTVSLELLGKATEIAKDYDTKVSALLLGS
                     KVEGLIDTLAHYGADEVIVVDDEALAVYTTEPYTKAAYEAIKAADPIVVLFGATSIGR
                     DLAPRVSARIHTGLTADCTGLAVAEDTKLLLMTRPAFGGNIMATIVCKDFRPQMSTVR
                     PGVMKKNEPDETKEAVINRFKVEFNDADKLVQVVQVIKEAKKQVKIEDAKILVSAGRG
                     MGGKENLDILYELAEIIGGEVSGSRATIDAGWLDKARQVGQTGKTVRPDLYIACGISG
                     AIQHIAGMEDAEFIVAINKNPEAPIFKYADVGIVGDVHKVLPELISQLSVAKEKGEVL
                     AN"
     gene            35286..36083
                     /locus_tag="OE968_000572"
     CDS             35286..36083
                     /locus_tag="OE968_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase/isomerase family protein"
                     /protein_id="HCP7217889.1"
                     /translation="MSTSDVKVYENVAVEVDGNICTVKMNRPKALNAINSKTLEELYE
                     VFVDINNDETIDVVILTGEGKAFVAGADIAYMKDLDAVAAKDFSILGAKAFGEIENSK
                     KVVIAAVNGFALGGGCELAMACDIRIASAKAKFGQPEVTLGITPGYGGTQRLTRLVGM
                     AKAKELIFTGQVIKADEAEKIGLVNRVVEPDILIEEVEKLAKIIAKNAQLAVRYSKEA
                     IQLGAQTDINTGIDIESNLFGLCFSTKDQKEGMSAFVEKREANFIKG"
     gene            36181..37026
                     /locus_tag="OE968_000573"
     CDS             36181..37026
                     /locus_tag="OE968_000573"
                     /EC_number="1.1.1.157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxybutyryl-CoA dehydrogenase"
                     /protein_id="HCP7217890.1"
                     /translation="MKLAVIGSGTMGSGIVQTFASCGHDVCLKSRTQGAIDKCLALLD
                     KNLTKLVTKGKMDEATKAEILSHVSSTTNYEDLKDMDLIIEASVEDMNIKKDVFKLLD
                     ELCKEDTILATNTSSLSITEIASSTKRPDKVIGMHFFNPVPMMKLVEVISGQLTSKVT
                     FDTVFELSKSINKVPVDVSESPGFVVNRILIPMINEAVGIYADGVASKEEIDEAMKLG
                     ANHPMGPLALGDLIGLDVVLAIMNVLYTEFGDTKYRPHPLLAKMVRANQLGRKTKIGF
                     YDYNK"
     gene            37113..38288
                     /locus_tag="OE968_000574"
     CDS             37113..38288
                     /locus_tag="OE968_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000786547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HCP7217891.1"
                     /translation="MREVVIASAARTAVGSFGGAFKSVSAVELGVTAAKEAIKRANIT
                     PDMIDESLLGGVLTAGLGQNIARQIALGAGIPVEKPAMTINIVCGSGLRSVSMASQLI
                     ALGDADIMLVGGAENMSMSPYLVPSARYGARMGDAAFVDSMIKDGLSDIFNNYHMGIT
                     AENIAEQWNITREEQDELALASQNKAEKAQAEGKFDEEIVPVVIKGRKGDTVVDKDEY
                     IKPGTTMEKLAKLRPAFKKDGTVTAGNASGINDGAAMLVVMAKEKAEELGIEPLATIV
                     SYGTAGVDPKIMGYGPVPATKKALEAANMTIEDIDLVEANEAFAAQSVAVIRDLNIDM
                     NKVNVNGGAIAIGHPIGCSGARILTTLLYEMKRRDAKTGLATLCIGGGMGTTLIVKR"
     gene            38484..39386
                     /locus_tag="OE968_000575"
     CDS             38484..39386
                     /locus_tag="OE968_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HCP7217892.1"
                     /translation="MFKKENQRYNLISYTNEEEMTLKEVLLDKLNFSVRSLSKMKREK
                     SVLVNGVYKKPSLKVYSGDLIEVKIDEEKANFEPQDLNLQIIYDDFDIIMVNKPPFMV
                     VHPTKSHYDKTIANGISYYIDNQKENVKIRFVNRLDMNTSGLVIVAKNAYAHHTLSTA
                     MSENKVEKKYITVVDGIIKENEGTIDEPIYRPTEDSIKRIIDERGQSSVTHYKVIERL
                     ENATVLEVSLETGRTHQIRVHMAHIGHGIIGDELYGYVDEDLINRQALHAYKLEFEQP
                     RTKEKLKFKADIPEDMKELISKLR"
     gene            39400..40404
                     /locus_tag="OE968_000576"
     CDS             39400..40404
                     /locus_tag="OE968_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HCP7217893.1"
                     /translation="MIIHKFIIHVLDKNSDVPILNDFEGKVNQEVDGFFQKAIKRIAK
                     DEDLRKGVFKDYNDNLIKNCCEQIIYDESTFLKNSKEIASYLFDVMKINAALESCDLA
                     ICLYTIKDEKSVAILKLDYKKLYTHSIEFVDDKFNIQMVSNEIGIPETLRQKQGALIS
                     LSGINDEFHLRLLDKDAEKEGSESKFVTEFLNAKKIDDDKYKTKVFKNTAENWITNAL
                     SNDIKQAEDVRSILNYTLKEKHEVDINDFVDNSIKDDELKDSFKEHMEEKGLDESFSI
                     DKKWVEKKLKKRSIKTDNGFDIKGNLTDFEDPMKYTVKQNQDGTIDIIIKNVTFYEEK
                     "
     gene            complement(40548..40775)
                     /gene="acpP"
                     /locus_tag="OE968_000577"
     CDS             complement(40548..40775)
                     /gene="acpP"
                     /locus_tag="OE968_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HCP7217894.1"
                     /translation="MFEKIKEIIAEQLGVDNLDEITMEASLMDDLEADSLDAVEIIMA
                     LEDEFGIEIPDEEAENFKCIGDICKYIEENK"
     gene            40947..41372
                     /locus_tag="OE968_000578"
     CDS             40947..41372
                     /locus_tag="OE968_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7217895.1"
                     /translation="MKYVGLLLTSVGMFLLIAVNFYYNSITLDMQRIEDYVMETNLIL
                     EDVAEKESYVSNEKEDYISRLMHVKKGIENSKTSFLIERYKEYKIKSIESLIYTISEE
                     KKDYLDEVDRYNKLGEKEINKLINKNFLEVTYLSITTYI"
     gene            41420..41626
                     /locus_tag="OE968_000579"
     CDS             41420..41626
                     /locus_tag="OE968_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7217896.1"
                     /translation="MTKLEDNMERFFGGCEGFFGNKMLIIIVIVFLLLCTDILEDLLC
                     DDNIWIWVILIVLLLFNFDDGCCC"
     gene            41808..41987
                     /locus_tag="OE968_000580"
     CDS             41808..41987
                     /locus_tag="OE968_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7217897.1"
                     /translation="MLDRFFGEEGCFGGGGWWIIVLFFLFLAFGDSWAEFDIMAWIPF
                     LIVLLILCCCGGCLE"
     gene            42021..42221
                     /locus_tag="OE968_000581"
     CDS             42021..42221
                     /locus_tag="OE968_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7217898.1"
                     /translation="MLDRFFGEEGCFGGGGWWIIVLFFLFLAFEDCWRDIDIMSWIPF
                     LILLLITCSCGGFFDGEVGCGC"
     gene            42474..43490
                     /gene="ccpA"
                     /locus_tag="OE968_000582"
     CDS             42474..43490
                     /gene="ccpA"
                     /locus_tag="OE968_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator CcpA"
                     /protein_id="HCP7217899.1"
                     /translation="MKGNITIKDVAKQAGVSISTVSRVINDSKPVTDEVKQKVLEVIK
                     ETGYIPNPLARSLVTKKSQLIGVIVPEVSDSFVNEVLNGIEEVAKMYDYDILLANTYS
                     DKEQELKSINLLRAKQVEGIVMISWIVEQEHINYIQNCGIPATYISKTARNYDIYTVS
                     TSNEEATFDMTEHLIKKGHEKIAFIMTSKDDTVLEMERLAGYEKALSNNNIELDKSLI
                     KYGGTDYESGYNSMKELLDDGIIPHAAFVTGDEAAIGAINAICDAGYKVPEDISVAGF
                     NDVKIARMYRPKLTTVYQPLYDMGAVAIRMVIKLINKELIENKKIELPYRIVDRESVT
                     ERKK"
     gene            complement(43613..44011)
                     /locus_tag="OE968_000583"
     CDS             complement(43613..44011)
                     /locus_tag="OE968_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7217900.1"
                     /translation="MKKLDTESLEKMAKQKNIDKDKIEKMADSYKGKSENELMEELIK
                     IGKNLDGRDEVVSKFKAFLDENQRKKLDNIMEKISDAENQRDTKPAKTKKAKPTKGKS
                     NSPAPKNTPGSQQKKSKSLFKKTKKSNPHE"
     gene            44223..45128
                     /locus_tag="OE968_000584"
     CDS             44223..45128
                     /locus_tag="OE968_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7217901.1"
                     /translation="MNNLLFLIGVIALSNGNISIFDDKNKSKGNNRVRKNKKNANDKL
                     SQSTHGNLRFDANDIKRGLRLMDLSEEDLEMGMEIITRTKKYMSRDERKILIKIESVL
                     DLVRGIKKLNNIDMVDTEDETDFFRKMDSDDKKNMMIKEIIDVFPEKRKNSVEKAIGM
                     KKKIDLFAELFLPDDFGEGGFSLSSLANINNLGSMNNLKLLGSLLRGDDSNNDDEDNN
                     DELNYEDEELDCEDKELDDDELTDEGEMEDNEDELVEDKNTGYENIENDEDIVYDEEL
                     YNINEQESEYNYNEKNTKTRAKKKR"
     gene            45243..45423
                     /gene="ssrS"
                     /locus_tag="OE968_000585"
     ncRNA           45243..45423
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="OE968_000585"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            45606..46823
                     /gene="cdeC"
                     /locus_tag="OE968_000586"
     CDS             45606..46823
                     /gene="cdeC"
                     /locus_tag="OE968_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exosporium morphogenetic protein CdeC"
                     /protein_id="HCP7217902.1"
                     /translation="MQDYKKNKRRMMNQPMSTMNEEEVYTDEINSEDMRGFKKSHHHN
                     GCNTDNKCECHDDCNPCNPCNPCKPNPCNPCKPNPCDDNCGCHDNCKCDCEPCEMDSD
                     ECFENKCGPECCNPISPRNFSVSNAVPFAIEANRIFDTMQFQTFTDATGPNGEPLTFE
                     TEVVEVFGSVPSAGQASVTIEKICLSNDGIVIDTGMTTLEDFDLDPLGDIVGRNCETT
                     FEFAVCGERNSECCRQGKGKSVAYKQRGLTVAVRNLVLELRGRCGCTEFVALAFPAVR
                     AGGGCKRRVDYVEFTFNTLSAPICLPADGRAVTLRQEYQTNLTVDCIGKSILKLECNE
                     CCEPFYELIIPNDIDLVLCLQETVSTLISEQIVVLASPNPIQPRLVDTFSKVCDFSQC
                     GPNHGSGKPSCHR"
     gene            complement(46923..48245)
                     /locus_tag="OE968_000587"
     CDS             complement(46923..48245)
                     /locus_tag="OE968_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HCP7217903.1"
                     /translation="MKVPYLVLSTVILFISNFIVRIFGFLYKIFLSRALGETGLGIYH
                     MIFNFLMICLAVTTTGIPTALSCLVAKRKALNDRHNTNALFISTLYISFFVALIISIV
                     ASFNSSFLSLKFLKDAKLNLFILAVCPAIVIITLSNVLRGYYYGIKNVKIPAIGQIIE
                     QIGKILFVFLLVMYINNKSMNCYIALLGISIGELSNIIFMLICLWRDSSFDNRYIISI
                     KDFYNSSMETLKMSIPITCNRMSNILLQSISSMMIPSRLALSGMTYQQSLSMYGIVSG
                     MVMPFIFLPFTVGSALIVNLIPTISQEMALRKRKSVIKKIKYSILLTLFVGILSSIFF
                     YFFGKDLCILVFKNTLAGEYLKAMFLVPLFMSLNQTLSGILHSIRKELASSINTITGM
                     LIQLIALYVFLPIPGLNIYAYIYTMTIVSIFTCLLHTIVLFKSLKSIR"
     gene            complement(48296..49090)
                     /locus_tag="OE968_000588"
     CDS             complement(48296..49090)
                     /locus_tag="OE968_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphatase HisJ family protein"
                     /protein_id="HCP7217904.1"
                     /translation="MFYDYHMHSSFSTDGKSTMEEMVKKSIELGLEEICFTDHVDYDV
                     YADDSFSIVYEDYFKSLETLQSKYKDKISIKKGIEFGVQTQLMDTYKKEAHQYPLDFI
                     ICSIHAIDTMDLYLGNYFKDKTQHEVYENYYLYLYNIVKNYKDYSVLGHLDLIKRYAP
                     YDTILDDRLFSDIIEETLKQAIYDGKGIEINTSCYRYNLPDLTPSKYILQMYKDLGGE
                     IITTGSDSHHISQVACEFDYIYSLLKNMGFKYVSKFNKLKPEFIKL"
     gene            49200..50645
                     /locus_tag="OE968_000589"
     CDS             49200..50645
                     /locus_tag="OE968_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HCP7217905.1"
                     /translation="MEKYRIDLNEKKSTKYIQIFNHIKELIINKELVEHEKLPPIRKL
                     SNFLQVNNTTIVKVYELLENEGYVYKIIGSGTFVSSLNSYKSGIDNRKNKIIVQREDL
                     IHFDNGNPSNDMFPIDSFKNAVNMALSKDGSSIFEYDEGLGSEELREKMVEYLSDGNI
                     KTTKENIQIISGAQQGIDIVCKGLISYSDVVFMEEPSYNGAIEVFKSRGAKIISIPML
                     DDGIDIGILKLKLEKIKPRLIYIMPNFQNPTGISYSTYKKKKLIELAEEHDFYIIEDD
                     FISDFVFESKDNRTIRSYDDKNRVVYIKSFSKILMPGLRIGIVEMPNELLKKVLWAKY
                     SSDISTPGLIQKSMYYYMNNFDWKNYLSHIEKIYTDKYKLAKNLINDKLSGKLKVRKS
                     CGGINFFLELPRGYTSQAFTNFMLNKGVSMLPGTYFFDNLVDDRFFRINIARPSMEEL
                     EKGISIISDNIDEFFCEYKNKLDIKSNKLFY"
     gene            50674..50883
                     /locus_tag="OE968_000590"
     CDS             50674..50883
                     /locus_tag="OE968_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 domain-containing protein"
                     /protein_id="HCP7217906.1"
                     /translation="MFDKKKLDRINELAKKNKEGILSADEIKEREILRKEYLENFRAH
                     FRSRLDSVKVVSPEEYEQYMKNNKN"
     gene            50903..52297
                     /locus_tag="OE968_000591"
     CDS             50903..52297
                     /locus_tag="OE968_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HCP7217907.1"
                     /translation="MNLKYEFKNAWDFERKENTIEQIMQYSSNYMEFLSKSKTERLSV
                     KEIIKLAKENNYISIDEAMEKGSISCGDKIYVINKEKAVALFVIGKNYIEKGMKIIGS
                     HIDSPRLDLKPNPLYQESNLGFFKTHYYGGIKKYQWTAIPLALHGIVILNDGTKVDIS
                     IGEEDSDPVFCVTDLLIHLAGDQMQKKLSEGISGEALNILIGNMPLEDEEKEPITANI
                     LKILNEKYNIVEEDLLSAEIEVVPAGKARDLGLDRSMVLGYGHDDRVCSYAAVKAILE
                     TEQPEFTSVALCVDKEEIGSKGNTGMHSKFFENTVAELIALEGDYCDIKVRRALANSK
                     VLSADVSAGYDPNFGEAYEKRNSAYMGNGVVLTKYTGSRGKSGCNDANAEFMSEVKRI
                     FNKGNVVWQTAELGKVDQGGGGTIAHILANQGAEVIDCGVGVLNMHAPHEIVSKVDIY
                     EMYKGYKAFFNINL"
     gene            52537..52722
                     /locus_tag="OE968_000592"
                     /pseudo
     CDS             52537..52722
                     /locus_tag="OE968_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896033.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
     gene            complement(52831..53997)
                     /locus_tag="OE968_000593"
     CDS             complement(52831..53997)
                     /locus_tag="OE968_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017752472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HCP7217908.1"
                     /translation="MKGGVRKRGKKWYYYFDAGIVDGKRKKVERVGGNTKKEAEKSLR
                     DAINEYENAGIVFDETNMSLSDYLNFWYKEYVLLNCKYNTQESYRNLIENHIEPRLGK
                     CKLKSINPAIIQEFLNNKSKETYTQNGEEKHYTKGVLKAIYVVLNAALKSAVYPYKLI
                     KENPVQYASIPKNVLKVKNESDNKTITLDEFNKILEIYPKNTNIYIPLLIGFHTGMRK
                     GEILGLCWDNVDLDNNIIKVRKNLIKRKVSEFELASPKTKTSIRDIKIGDTLSRILKE
                     EKLNQKKQKIKIGKWYKETEYDWVCRKKDGSFVNHNNIDAAIRTINKKLNINFNFHCL
                     RHTHATLLLENGANVKYIQQRLGHSQLSTTMDTYSHVTSKMESETIDILEGILQ"
     gene            complement(54135..54341)
                     /locus_tag="OE968_000594"
     CDS             complement(54135..54341)
                     /locus_tag="OE968_000594"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7217909.1"
                     /translation="MNLSFNKKKKFELSKEELELIENWLGNKYAGDMTIPAIVDFSLE
                     TDIEYEKIVVYLAEKVLESRDKKH"
     gene            complement(54400..54621)
                     /locus_tag="OE968_000595"
     CDS             complement(54400..54621)
                     /locus_tag="OE968_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCP7217910.1"
                     /translation="MLKELRKKKKLTQIELAKRVGCHRSQISRLENNEDKDLTIPILI
                     ELEIALGLEEKYLVNYFADEYIKKRKLHK"
     gene            54905..55042
                     /locus_tag="OE968_000596"
     CDS             54905..55042
                     /locus_tag="OE968_000596"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7217911.1"
                     /translation="MNKTKYYDILKLNLLMKKLKELDKNKINEYKIKVKEIHKINKKE
                     E"
     gene            complement(55079..55474)
                     /locus_tag="OE968_000597"
     CDS             complement(55079..55474)
                     /locus_tag="OE968_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCP7217912.1"
                     /translation="MNRIKELREEKGISLDKLSEDLHINKSTLSRIENGLREPKKSTI
                     EEYANYFDVSTDYLLGRTDVRNSLFINKNEKDYDAENFKTEKELIENMYLDEDMKEVF
                     NIFSELSPDAREKALKVAELFLLDEKNKK"
     gene            55653..55916
                     /locus_tag="OE968_000598"
     CDS             55653..55916
                     /locus_tag="OE968_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HCP7217913.1"
                     /translation="MYLNRLEGLMKENRHTQKNVADILGLSSYGFRLKLKGKNEFKAS
                     EIKKISKLYNVSADYFFSDEVAKIAIKEERGNNNEESNHNQAK"
     gene            55885..56673
                     /locus_tag="OE968_000599"
     CDS             55885..56673
                     /locus_tag="OE968_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor KilAC domain-containing
                     protein"
                     /protein_id="HCP7217914.1"
                     /translation="MKNLTIIKQNNQFLVESREVAELIEKKHDNLLRDIRGYKKILED
                     SSNLRSQDFFIESTYINTQNKIQPCYLLTKKGCDMVANKMTGEKGIIFTAIYVTKFEE
                     MEQELKEQQPKLPTTYKEALQQLLIEVEEKEQLQLENQEKDKVIQLQQPKVLFADSVA
                     SSDNSILVGELAKLLRQNGIDTGQNRLFDWLRNNGYLIKRKGEDYNTPTQKSVDLGVI
                     ETKEGTRVHPDGHTSITKTPKITGKGQIYFINKFKSSKQLSMLS"
     gene            complement(56830..57000)
                     /locus_tag="OE968_000600"
     CDS             complement(56830..57000)
                     /locus_tag="OE968_000600"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7217915.1"
                     /translation="MSNKDIYTREEDKRFTLRINKLLFEKIEQLAQKDKRSIGREIEF
                     ILEKYFEDNPLE"
     gene            57143..57310
                     /locus_tag="OE968_000601"
     CDS             57143..57310
                     /locus_tag="OE968_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Arc family DNA-binding protein"
                     /protein_id="HCP7217916.1"
                     /translation="MTNERVRFTFRLPAPLLEKIKNRASIEGSSMNSLILHILWNYIQ
                     EIENEEVGKYE"
     gene            57303..57953
                     /locus_tag="OE968_000602"
     CDS             57303..57953
                     /locus_tag="OE968_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7217917.1"
                     /translation="MNNIQIFKNYNFGEIRTIEIDGKPYFVATDIAKALGYSNTRDAV
                     KKHCKWVAKCDIPHPQSDSKALKVNVIPEGDMYRLITNSELPNAEKFESWVFDEVLPT
                     IRQTGQYQAQQHVITELTGTIGDLKGTIKEYKKLCKITCSKKQQYSKYIKNRLDIDKA
                     NKEYNQVKARLFLILGVEKWEDIDFDTSNNLIQIIDDCIRVIKSERPYKQLSYFEN"
     gene            57988..58185
                     /locus_tag="OE968_000603"
     CDS             57988..58185
                     /locus_tag="OE968_000603"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7217918.1"
                     /translation="MKISFESVVNNVNNETELILSKEELQIAKRILNTLNENEQSILS
                     SKDILDFCKEALKYNLVPTFV"
     gene            58425..58622
                     /locus_tag="OE968_000604"
     CDS             58425..58622
                     /locus_tag="OE968_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCP7217919.1"
                     /translation="MAINDNINKILKDRDLKAWKLAKEIGVDSGNLYAILRGENKNPT
                     IDTLIKIADYLDITLDELVGR"
     gene            58652..59095
                     /locus_tag="OE968_000605"
     CDS             58652..59095
                     /locus_tag="OE968_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCP7217920.1"
                     /translation="MSKLGNISNFNLDKQEDKSFNDLDNISICFSEGIRKVVEMNLNN
                     YKNKISKYLNETSKIELLEPKELTIVISKGYPDYLMSVEEASKRLKIDKVFGYELIKN
                     GLLKSVDIGATKVSSYELDDFITRNQGKNIKEMLREMKEIREGVI"
     gene            59096..59242
                     /locus_tag="OE968_000606"
     CDS             59096..59242
                     /locus_tag="OE968_000606"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7217921.1"
                     /translation="MNVRVLIAYVQFCNDKQIKASFEGLRKYNRDIELVNLYLPSKLK
                     IKGD"
     gene            59245..59562
                     /locus_tag="OE968_000607"
     CDS             59245..59562
                     /locus_tag="OE968_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7217922.1"
                     /translation="MKSLTIVRNAVEQQLNRANLEINKNEELYTKLRKKEKRDVLDEI
                     ELSNALREKSVNERLKIFAESLLKIIDTQIEIKEYEESEDYKIFELISEEIERDRPID
                     IQI"
BASE COUNT        24326 a         6335 c        10304 g        18658 t
ORIGIN      
        1 ttaggtagta cctcaaaagt cagtgttaag tttaaagaaa aaccagatgc agatagcatt
       61 acattaaagt ataaatgcta tgatatgcca ttggatacaa ctttaaacta caatcaatca
      121 actgagtcat atgaaggaac tatcaattat aataaagacc cagaatatct aaatgtttgg
      181 gaactacaag ggataacaat aaacagcaaa aataatccta aaactttaaa caaacaagaa
      241 ctagaaaaga tgggattaaa tttaaaagac tataatgtaa cacaggaatg tataattgaa
      301 gatataactt ctagaaaaga tgtaaataaa tatttaagaa aaacttctgc acctattaca
      361 gaacttacag gaagtgatag atacgaaaca gcagttaaaa taagtaaaga aggctggaaa
      421 aatggttcag ataaggtagt tataataaat ggggatgtaa gtatagatgg cattatatca
      481 actccactag caactacata taatgcgcca atacttttgg ttgaaaaaaa caatgtacct
      541 aatagtgtaa aatcagaatt aaagcgttta aatcctaggg atgtaattat aattggagat
      601 gagaatgcta tttctaaaac tactgctaat caaattaaat cgactgtaaa tgctagtcaa
      661 acacgtctaa agggctctaa tagatatgag acatctttat tgatagcaaa ggaaatagat
      721 aaaaatcatg atgtggaaaa agtgtacata acaaatgcta atggcggaga agtggatgca
      781 cttactatag cagcaaaagc aggtcaagac aagcaaccaa ttatattaac tgataaaaat
      841 agtattacag acaacacata taaatggtta aagagtgagg atttacaaaa tgcttatttt
      901 ataggtggcc ctcaaatgat atcaacaaat gttataaata aggtaaatga tataactaaa
      961 gataatgtta ctaataatag agtatatgga gcagatagac acgaaacaaa tgcaaacgta
     1021 ataaaaaaat tctatacaga tgatgagcta gaggctgttt tagtagctaa atcagatgta
     1081 cttgttgatg ctttagcagc aggtccattg gctgccaact taaaatctcc aatacttata
     1141 acaccaaaga cgtatgtatc tgcataccat aaagaaaact tagaagctaa atcggctaat
     1201 aaggtatata aaataggagg aggattgact tctaaggtaa tgaactctat agcatcatca
     1261 ttatctaaac acaatacgac tccaacagaa ccaggaaata gtgggggtaa gacagttatg
     1321 attgacccag gacatggtgg ttcggacact ggaacaacag gtaaaccatt agggggtatt
     1381 aaagaaaaag actatacatt aaatacttca cttgcgacaa ctgaatattt acgttcaaag
     1441 ggattcaatg taataatgac aagagataca gataagactt tatctcttgg aaatagaact
     1501 gctttatcta actctttgag accagattta tttacgagta tacactataa tgcatctgat
     1561 acaactggga atggtgtaga agtattttat aagcttaaag ataaagatgg aggaactact
     1621 aagactgtag ctacaaatat attaaataga atcttagaga aatttaatct aaaaaataga
     1681 ggtgcaaaaa caagaacact atcaactgac cctacaaaag attatttata tgttttaaga
     1741 aataatgata tgccagctgt acttgtagaa tgtgcatttt tggataatga gaaagatatg
     1801 agtttactta atacatcaaa taaagtaaaa gaaatgggta cacaaatagg taaaggcata
     1861 gaagattcat taaaatagtc tacaatgaga gcatagaaaa atttaaaata aattaatcta
     1921 taattttaaa tttaaactaa agctataaga taagaatgta attataatag taataaagac
     1981 tgtatataca ttgtgcatat aaatgcgaaa tgaggtatat acagtctttt tataattaat
     2041 tgtaaaatga tttatgttat atgaaaaatt tacatatatt aaggctacag ttaattgtca
     2101 agagctggag tattcatttg taatacacaa tataagctta attactatat tttattgtgt
     2161 gttttttgtg gatttttatg tcaataaatg atatagtata gataattaaa tgtattaaat
     2221 atatttaatt tttttatttt ttgagtttta taagtttatt tttatatatt acttatatat
     2281 tacttatata ttatttatat tttgggttag atacactttg acatattttc aaaagttaaa
     2341 agattaaaaa taaagtagaa atttatgtta agtaaggaga ttaatatgag aagaaataca
     2401 aaattattaa caacagggat tctttcaatg gcaatcgtcg cacctacaat ggcatttgct
     2461 actgaatcta atgctatgga aaataacgct gatttaaata taaacttaga gaaaaaaagt
     2521 atcgttttag gtagcaaatc aaaagttagt gtcaaattta aagaaaaacc agatgcagat
     2581 agcattacat taaagtataa atgctatgac atgccattgg atacaactct aaattacaat
     2641 caatcaactg gggcatatga aggaactatc aattataacc aagacccaga atatctaaat
     2701 gtttgggaac tacaagggat aacaataaac agcaaaaata atcctaaaac tttaaacaga
     2761 caagacctag aaaagctggg attaaattta aaagactata atgtaacaca ggaatgtata
     2821 attgaagaca taacttctag aaaagatgta aataaatatt tgagaaaaac ttcttcacct
     2881 attacagaac ttacaggaag tgatagatat gaaacagcag ttaaaataag taaagagggt
     2941 tggaaaaatg gttcagataa agtagttata ataaatgggg atgtaagtat agatggcatt
     3001 atatcaactc cactggcaac cacatataat gctccaatac ttttggttga aaaaaacaat
     3061 gtgcctaata gtgtaaaatc agaattaaag cgcctaaacc ctaaagatat aattataatt
     3121 ggagatgaga atgctatttc taaaactact gctaatcaaa ttaaatcaac tgtaaatgct
     3181 agtcaaacac gtttaaatgg ttctaataga tatgagacat ctttattgat agcaaaggaa
     3241 atagataaaa atcatgatgt ggaaaaaata tacataacaa atgctaatgg cggagaagtg
     3301 gatgcactta ctatagcagc aaaagcaggt caagacaagc aaccaattat attaactgat
     3361 aaagatagta ttacagacaa tacatataaa tggttaaaga gtgaggattt acaaaatgct
     3421 tattttatag gtggtcctca aatgatatca acaaatgtta taaataaggt aaatggaata
     3481 actaaggata gtgttactaa taatagagta tacggagcag atagacacga aacaaatgca
     3541 aacgtaataa aaaaattcta tacagatgat gagttagagg ctgttttagt agctaaatca
     3601 gatgtacttg ttgatgcttt agcagcaggt ccattggctg cgaacttaaa atctccaata
     3661 cttataacac caaagacgta tgtatctgca taccataaag ataatttaga agctaaatca
     3721 gctaataaag tatacaaaat aggaggagga ttgacttcta aggtaatgag ctctatagca
     3781 tcatcattat ctaaacacaa tacgactcca acagaaccag gaaatagtgg gggcaagaca
     3841 gttatgattg acccagggca tggtggttca gcacctggaa attcatctgg aggaatgatt
     3901 gaaaaagatt acaatttaaa tacttcactt gcaacaactg aatatttacg ttcaaaggga
     3961 ttcaatgtaa taatgacaag agacacagat aagactttat ctcttggaaa tagaactgct
     4021 ctatctaatt cattgaaacc agatttattt acaagtatac attataatgg ctcaactaat
     4081 aaacaaggtc atggtgtaga agtattttat aagcttaaag ataaaaatgg agggactact
     4141 aaaactgtag ctaccaatat attaaataga attttagaga aatttaaact tacaaataga
     4201 ggtataaaaa caagagtact tcctagtgat tctacaaaag attatttata cgttttaaga
     4261 agtaatgata tgccagctgt acttgtagaa tgtgcatttt tggataatga aaatgatatg
     4321 agtttaataa actcatctgc aaaagtaaaa gaaatgggta cacaaatagg taaaggaata
     4381 gaagattcat taaaataaat ggaaataaaa atatttaaaa acttaatgta aatttatagt
     4441 tgtaaattta tactaaagtc aaaaaatgaa atataagtgt atcaatagta agactgtatg
     4501 tacatttgca catgtgaatg caagtatata tacagtcttt ttttgtagtt aaatgcaata
     4561 atttgattgt gttttgtaaa atacacaata tgatataatt agataatata cacttaattt
     4621 aattgaggaa ggtgattata tggaatattt atttgaaaaa agtagtttaa aagaatatgg
     4681 aaatgaagct ttagataaat atagagaatt attagataaa actggtaata attcaaggtg
     4741 tattcttttg ttagtaccaa acaataacac aaagatacga tatgaaaggg ctctaagatt
     4801 aaattatagt gaagaactga aagtaacaac atatataagt tttgtgaaga aagaattagt
     4861 taaatactgg ccactaataa tagaaaaatg tgatggaata agtacaaagg ttgtatctcc
     4921 aacatttata tcaaatagtt taagtgaata tttaatagtg caaaaagtta aggaaaaaag
     4981 gatacaagaa ggatattttg aagatattac aggaaccaat aaatccatag caaatagtat
     5041 aatgactaac ataaataagt ctgcatttaa tttaattgat tttgatttta ttggagaaaa
     5101 aatatattca tcaaagaaaa ataaagatag tatatataga ttttcataca ctcaaatgga
     5161 tgaaattata tcatattata taaattcctt actatcaaat tcaattttag ataatgcatt
     5221 aagcatatat ttatacaatc aatacctact taatgatgat ttttatttaa aaaacttatt
     5281 tacagaagtg agatatataa ttgtggatag ccttgaaagc tcaagtaatg cagaagttga
     5341 ttttataaca gaagcattgg ataatacatt acaaagttat atatattttg attatagtag
     5401 ggattattct gtatttaata atgtggatat agactatata aatgagaaaa taatatcaaa
     5461 aattaagcct aaagaagaaa atattaaaaa gaaggagatt agaatagaag atttatactt
     5521 attacctgca aatatagaat taaatcaatc aagtcaatta tataatgaaa tgttagattt
     5581 aataagtgaa aaagttatat ctcttataga agaagatgta tctccaagag atatagcaat
     5641 tatatctcct ataaacaata gtatattgga gcatcaaatt agagattctt tgatagaaaa
     5701 aaatatagat gtttttagta ctaagaagga taaaaaagct gtggattatc catatgggaa
     5761 tgcattggta gtggctacat gtatattcta tggatattta gattttataa aagatgatga
     5821 atacttaagc tttttagaaa ctcttttaga aataaatagg ataaaagcat ttaagatttt
     5881 taatgaaaca agacatttaa gtattgataa tatagatgaa catagtcagt atcgtgatat
     5941 tttacagtat attgaagaaa aaaagaagag tgatataaaa atacatgaat ttttaactca
     6001 attttacata gataaaatgt taaatttaaa agaaggtaaa aagaatgttg ggttatgtaa
     6061 aaagataata gctgaaagtg agtcttttag tgaaagttta agtctacttg ggatgaaaaa
     6121 agaaaagata tttgtagaag ctttaaaaag tacaataaac gattattact ctgttgtcga
     6181 tatagaagag ttgaaatcca aagacaaaat agtaataact actccttatt catatatatc
     6241 atcaaatata gatagaagta tacaaatatg ggtagatata ggaagtaatg cttggaatat
     6301 gaaaatagaa aaagatataa gtaatttaat tgtacttaga aaatcttttg aagaaaaaaa
     6361 gatttataca aatgaaatgg aagaatatta taaaaaatat tatctataca atacagtata
     6421 taatttgtta ttaaatgcaa agaaaatcta tgcatttaaa agtgaatatg cgattaatgg
     6481 ttatatccaa gagagtatat tatatagtat acttttaaaa atctcacata aaggagataa
     6541 aaattatgat taatataaat tatagagaag accagatacc aataataaat tacgataatg
     6601 gtactatggc agtaccagca gtaccaggtg ctggaaaaac atttataata acaaatttag
     6661 tagctaaact attacttgaa cagaaacata agagtggtaa aatattaatt cttacatata
     6721 tgaatagtgc tgtaaataat tttaaaggta gaataagaaa gattcttgaa gagaataaaa
     6781 tagatgatac taattcgtat gaagtaatga ctatacacag tttggctgta aaaataataa
     6841 aggaaaagcc agaagttgta atgttaagtg aggattttaa catagctgac gatttgcaaa
     6901 aaagtattat attaaatgaa tgtataagta gatttagatt tgaaggtgga gaaagagctt
     6961 ttagatggtt tttaaaggag caaaaagatg aacgctggaa agaaataact cttgaagcct
     7021 gggaaagagg tttttttgaa tttgcaggaa atgcaataag tgaacttaag tataagggaa
     7081 tttctccaga taaacttgaa gaaatattgt caagaggaca caaaggaatg cttaaaatta
     7141 ttttaccaat atataaattg tatgatagaa aattaaagca aaatggattg ctagattatg
     7201 atgatatatt aattttagca gaaaaaactt taagcttaga cgaagggctt agaaagaagt
     7261 ttcaaactag atacaaatat atatttgaag atgagtgtca ggactcaaat gaaattcaag
     7321 gtaatataat aaaaattata tctagcgaaa ataaaaacct agttagagtt ggagatataa
     7381 atcagagtat aacaggaaca ttttcatcat cagaccctaa attttttaaa gaatttataa
     7441 atagtgcaga tttctgttat aggatggata tgtcaaatcg aagttcaaaa gatatacttg
     7501 atttagcaaa cactcttgtc aagtatgtta caaaggaatt tagacaagaa gaatgtagac
     7561 atgctcttga agatatgcaa ataaaaactg tgccaaatgg aatgggatat aaagaaaacc
     7621 ctaatccaga acattataat ataaatgtaa agtggtatga gagttggaaa attgaaatag
     7681 agcaaactgc tagatacgtt aagggtataa aaaataaata tccagataaa agtataggta
     7741 tattggttcc atttaatgaa caagtgacac aagttgctaa agaacttaga gagaataatc
     7801 taacctttga agaattagga ccaaattctt tgaataaaag gaaggttata aacaacatag
     7861 catatattat tgattttatg ttacattgtg atgatgtaga aaagttaata gttgtactta
     7921 ataaagtttt tatagatact gataatgaag aagaaataaa gtatttttta gaagaattaa
     7981 aaaactattc taccgaagaa attatttata attttgaatt tagtaagtta gataatgatt
     8041 taatagaatt taaagaagaa agtgatatat acttaagttt taaaagagga atagatatta
     8101 taaaacagat attagaatat ccaataataa ggttagacct cttagttttg tttattggga
     8161 aaaaacttag tttagaaaaa gaagataaag ctgtactgga ttatatatct ttttatataa
     8221 agtatctagt atcagaaaat ataaatatgg atttagaaga tgtatataat ttattgtttg
     8281 atgtaaagaa cagggtgttt aatcatataa tagatgtggt atatgagata aatggatatg
     8341 aaccagagcc tggtagtata acactatgta actatcataa atcaaagggg atggaatggg
     8401 attgtgtgtt tttactaggt cttgttgaat ataatttccc tgacaatatt aatcaaaagt
     8461 ttcagagtga taaatggtat ctaaaagaaa aatataaaaa ccctatggca attattaaat
     8521 cagaagttga agctatatta aaaggaagta tttcaacaga ttatgctcat aaaacgaaga
     8581 ttgattctat aaatgaaaag attagacttt tatatgtagg gattactaga gcaaaggaaa
     8641 tgttagtact ttcaggaagt gcttatagag atgaaagtga tatagggaat aagagaaaag
     8701 agcaaaaacc atgtatatat ttaagcagac ttaatcaaca tattattgaa aaaaggtcaa
     8761 attaatatat aataagttat taaaagattg tttgaaatat atctaaaaga ggataaaaca
     8821 atatgtacag taagtaacta ctaaaaaata aagttaagag agaagtgata tgagtgaacg
     8881 ataaattaaa atatttttct tatagtcaaa attcaattaa cacatataaa tcatgtccat
     8941 tgaaatttaa atataaatat attgatagaa taaattggaa aaatgatgat gttggtagta
     9001 gagagtatta tgaaacttta aaaacaggaa gagattttca tttgatttgt gaaagatatt
     9061 ttagcaatat acctcttgga atctatttta atgaggatga taaaaatagt aaaaagtttt
     9121 taaagtggat ggaaaatata aaaaaagttg ttcctattga aaaaggaaaa acgtatttgc
     9181 cagaatatga agtaaggatg acattaaatg gggatataat acaggcaaag tatgatttag
     9241 ttgtaattgg aaataacaat atagaaatat gggattggaa aaccgagtct aaaaagattg
     9301 actataaaca cgtagaaaat agaatacaaa ctattgttta tatgttttta gcaaaagaag
     9361 taatacctaa agttttaaaa atggacataa atgttaaaga tataaatatg agatattatc
     9421 aacctgaatt tgatgactta ccaattacca ttttatatga tgaagaaaaa catgaagcaa
     9481 atagaaataa aattcaaaat tatataagta tgataaaaaa cactaattat gaagaacata
     9541 catacgaaga caatctatac aatgatatag aaaaggtata taataaagaa gaacgtatgt
     9601 gctatagaaa taaaaagcat tgcaagtatt gtgaatttaa taagttatgt aatggcaaag
     9661 aaatagatta tagtattttg gaggcggaaa tttatgggac ttaggtttgt attaggtaga
     9721 agtggaagtg gaaaatccac ctatatacta gatgagatta aaaaagaagc tcaaaaaaat
     9781 gaaacgacat caattatact tttagttcca gaacagtaca catttgaggc tgaaaataga
     9841 gtaagtaaac tatttttagg aaaagaaaaa gataagtatc taagagttag ggtacttagc
     9901 tttaagacac taagtaatat agttttttca caagtaggag gattgacaga tgtaaatata
     9961 aattctagtg gaaaagcaat gatggtatat agagctattg aagatgtaag tgaagaatta
    10021 aatgtatttt caaaatcaaa atcgcagtct ggttttgtaa gctcaattac agatatgata
    10081 tcagaaatga aacaatacaa tataagccct gaaatgttag aaaatatatc tggagaattg
    10141 gataatgaaa ctttaagttt aaaattaaaa gatataagta aaatatataa ttcttttgaa
    10201 gggaaattgc atgaaaatta tgtagatgct caagatatgt taacttcatt ggcaagtaaa
    10261 attgaattaa gcagttattt agatggagct tgtgtttata tagatgaatt tacaggtttt
    10321 acaccaaatc agtacaatgt cataaagagt atattaaata agtctaaaag tgttaatatc
    10381 tctttgactg tagatgatat caactatatt gggtacagta aatctgatat gttttccaga
    10441 acgaaattta cttattcaaa attgactcaa ttgtgcaacg aagaaggcat aaaaatattg
    10501 ccacaagtaa atttaaacac aggtgttata aaaagatttg aaaaagttaa ggaattacag
    10561 cacttagaaa gattttataa tgcttatcca tataaaatat attcaaatca aactgaaaat
    10621 ataaagataa aagagtttaa caatttatat tcagaggtgg aagagatagc cagagaaatt
    10681 gtacatttag ttagagataa gaatgtcaga tatagagata taaccattgc tacaagagat
    10741 ttaaatagat atgatttttt agtacactct atatttaatg aatataatat accaaacttt
    10801 atagataaga agagagaggc aaaaagtaat ccaatagtta ttttaattat ttcagcttta
    10861 gaaatgaaga atagacgata tgggtatgaa actatgttta ggtatttaaa aagtggactt
    10921 ataggaattg ataatgatga tataaattta ctagaaaatt atgtgttggc taatgggatt
    10981 aaaggtaaaa aatggtttga tgaaaaatgg gattatagaa taacccaaag tctttcaggt
    11041 caagaaagtg aatttgaact ggaattaaaa gagaaaataa atgaaataaa aaatagagta
    11101 ttagagccta tagtaatttt acaagaaaaa ttaagaggaa aaaatagagt aaaagaaatc
    11161 tgtagatata tatatgaatt tttattagat ataaatatgc cagaaactat agaaagttta
    11221 ataataaatt ttaaggataa aggggaactt gatgttgcaa atcaatactc acaagtttgg
    11281 gacatagtag tggacatatt agaccaaatg gtggaactta tgggtgatga aataatttct
    11341 ttagaaaaat ttataaaatt aataacctta ggttttgatg aatatgaatt aggactggtt
    11401 cctcctagta tagaccaggt acttgtaagt agtgtggata gaatgaaaaa tccagacacg
    11461 aaatatttat acctagttgg aactactgat ggtgtgtttc cgctgattac aaaggatagt
    11521 ggaatattga gtgataatga tagggaaagt cttggaaaca aaggaatcga agttgatatt
    11581 gatagtaaga ctaggagttt tgaagaacag tttcttgtat ataaagctct tacttcgaca
    11641 tctaagaatt taaccataac atatccaata tcagaccatg aaggtaaaac gcttagacca
    11701 tcaataatta tatcaagact taagaagata tttccaaata tagaaaataa aagttattta
    11761 gtggaagaaa ataaaagcac tgataaagat atacttaaaa aaataacggt taaatcccct
    11821 acatttaatg aacttataaa cgtaataaaa aattatgaca gtgatggtta caatacagaa
    11881 gagattaata gtatttggtt agatatatat aggtactatt taaaagatga aatctacagt
    11941 tctataacaa aaaaagttat aaaaggtctt agttatacta atcaagttca taagattgaa
    12001 gagaaaaaaa taaggtcatt gtataaaagt aattctctta gcatatctag gcttgaaaaa
    12061 tatgctgaat gtccatttgc ttattttata caatatggtc taaaagcaaa aaagcgtaaa
    12121 gagtattcat ttacaccacc agatttagga acttttattc ataatatttt agataggttt
    12181 tcaaaagaac ttttacaaga taatttaact tggagagata ttgatgaaaa atatatagaa
    12241 ttaaagatag gtataatagt tgatgaaata attttaaaga taccaggata tatattaaat
    12301 agttctgaga ggtataaata ccttgcatat agattaaaga atatgttgac aactgctata
    12361 actataatta gtcagcaaat aaaacaaggt tcatttgaac caatagatta tgaagttaaa
    12421 tttggcaaca atggaaaata tccacctata aaaatggtgt tagaaaatgg acaagaagta
    12481 agtttaattg gacaaataga tagagttgat gaatttgaag aaggagaaaa taaatatata
    12541 agaataatag attataagtc aggcaataag tccataagtc taacagaaat atattatggt
    12601 ctacaattac aattacttgt gtatttagat gcaatccttg aaagtgcaaa ggatgaagat
    12661 ataaatataa atccagctgc aatactatat tgtagaataa ataatccaat agcaaaattt
    12721 aatgaagata aagatgatga agaaatacaa gaagcaatat taaaagaact tagaatgaag
    12781 gggcttgtag taaaagactc tcacatagtt aaagagatgg ataaatcatt aatagatgga
    12841 gaaaggaaaa actctttagt aataccagta ggtcttacta aggatggaaa tgtaggtaaa
    12901 agtacttcag caataagcta tgaggatttc aaactgctta gaaaatatgt aaggcatgct
    12961 ataaaggatt tatgtgaaga aatgttaagt ggagaaatac gtatagctcc atataaacat
    13021 aaagatggaa catcatgtga cttttgtgat tactctgcta tatgtcagtt tgattcaact
    13081 ataaaagata acaagtataa aaatttaaat aataagagta atgaagagat aataaaaatg
    13141 atgaaaggag atgttaatta gtgagttctc ctaaatggac aaaagagcaa ttagaagtta
    13201 tagaaagtag agaatgcaat ttattggttg ctgctgctgc tggttcagga aaaacagccg
    13261 ttctagttga gcgtataatt caaatgataa caagtagaga aaatccaatt gatatagata
    13321 agttattagt tgttacattt actaatgctg ctgcgtcaga aatgagagag aggatagggg
    13381 atgctatagg aaaagcctta gatgaaaacc cagaaaataa acatttacaa aaccaacttg
    13441 ttttattaaa taaatctagt attacaacaa tacactcatt ctgtttggat gttataaaat
    13501 caaactttca tagaataaac ttagacccta atttcagaat aggagaccaa actgaatgtg
    13561 ctattttgaa acaagaagca atagaggaag tatttgaaga tttatatgaa gaaagagatg
    13621 aggggttttt aaatttagtt gaaagttatg cagaaagagg aggagataaa gaagtacaag
    13681 atattatctt gggaatatat tcatttgcaa tggcttctcc tgaacctaaa aaatggttga
    13741 ttgactcagc agaacgattt aatattgatg aaaattttga tttttcacag tctatttggg
    13801 ctagagctat attagatact gtaaaaatag agattaatgg tctttgtcta aatatggaaa
    13861 gggcattaaa agaagtggaa tcaatagaag aattagaaac ttttgcagaa aagttatccg
    13921 ttgaatataa aaaaattgct gacatttcac aagcatgtaa taaatcttgg gatgaggcat
    13981 ataaaaagat ggcaagtatg tcctttgaaa attatgtaaa aggagtaaaa agaatttcaa
    14041 aagatgctcc ttcgtatata aaagaatcaa aagaaaaggc aaaaactata agagataaga
    14101 ctaagaagtc tttagaaagt atagtaagtg ctacattcaa taaagataat gattctatta
    14161 gagaagaaat aaaatatctt tataacatag ttaaaccaat atctagtgtt gtactgagat
    14221 ttgaagagga atatagcaat aagaaaagag aaaaaggaat aatagatttt aacgatatag
    14281 agcattttgc attaaatata cttacagatg tagatgaaaa aggtaatatt gtaccttctg
    14341 atatagcagt tggatataga aacaagtttt atgaaatatt tatagatgaa tatcaggata
    14401 gtaatctagt gcaggaagta ctgcttaaag ctgttgcaaa tacagaaact ccaaatagat
    14461 ttatggttgg tgatgtaaaa cagagtatat atagatttag acaagcaaag ccagaattat
    14521 ttttgcaaaa atataataac tataatgata aaaagggaag ctcccataga aaaataatgc
    14581 tttacaaaaa ctttagaagt agagaagaag ttgtagatgc tgtaaattat atatttgaaa
    14641 atataatgaa tgagaatata ggagaaattg aatatacaga aaaagaaaga ctaaatttag
    14701 gtgcaaattt taatgtggat acagacgaga aatctattat tggtggagca acggagatac
    14761 acctaataca aaaagataat aaacttgatg atgatattat aaatgataaa gacgatagaa
    14821 ttaataacaa agaaaatgaa atagaggaag aagaaaaatt agataatata caacttgagg
    14881 ctagaatggt tggaaacatt atcaaagatt taatgaaagt caatgaagat ggaaaaattc
    14941 aaaaggtcta tgataaggga atagatggat atagacctgt ggaatttaga gatatagtta
    15001 ttcttttaag agctacatct gcatgggctc cagtgtttgc agatgaattg atgaatatgg
    15061 atataccaac gtatgctgat gttggagtgg ggtattttga tacgattgaa ataaaaacaa
    15121 tattgtcatt acttcaaata atagataatc caatgcaaga tatacctctt atatctgtat
    15181 taaaatcacc tatatttgga tttacaccag aggatttgat tgatattaga gttcagagta
    15241 aagataaaat tttttatgag gttttaaaaa gtacagcaga gtatgatgga tttacagatt
    15301 ctcaaaatga aaatgagtct gagtttatac caagtgaaga atgcataaac aaaagtaaag
    15361 attttttaat taagctaaag gaatttaaag aaaagtcaat gtacatgagt acagatgaat
    15421 ttatatggta cttgtacaca aggactggat actatgccta tgttggagca ttgccaggtg
    15481 gaagtcaaag acaagctaat ttaaaagtat tgtttgagag agcaaaacaa tttgaagaaa
    15541 ccagtcttaa aggaatattc aactttgtaa attttataga gaaattaaaa aaatctagtt
    15601 ctgatatggg aagtgcaaaa acacttggtg agaatgcaaa tgttgttaga ataatgagta
    15661 ttcataaaag taaaggtcta gaatttccag tagtcatatg ctctgcaatg ggtaaaaatt
    15721 tcaatactca agattttaaa aagagtattt tatatcatca taatttaggg tatggacctc
    15781 aatttgtaga ctatgagaga aggatttctt ttccaagtat agccaaagaa gcattaaaaa
    15841 gcaaaataaa tatagaaaat ttatcagaag agatgagagt tttatatgtt gcatttacaa
    15901 gagctaaaga aaaattgatt ataactggtt ctactagaaa tatacaagat agtataaaga
    15961 gatggtcaaa tggaattgaa agtttagata caatatcaca atacgagata ttaaaaggta
    16021 aaaatttttt agattggata atgccttgtg tattaagaca tagggattta tctaatctac
    16081 tagaagaagt aggattagac gcagttttta atgttgaaca taattcaaaa tggtatggaa
    16141 agttgtggaa taagagtgat attttagtgg aaaagaagag tgatgaagaa aaagaaagta
    16201 ttgaagaaat tcttgaaaaa atagatgtag ataatcctga tagtgattat tacagtgaaa
    16261 tagaagaaaa attaaactat atatatccat atgaatttag tacaagaaaa cctgctacta
    16321 tatctgttac agaaataaaa aagatacaaa ataattatga agaagagtta ataaatacta
    16381 tatttgaaca aaaagtaata ttaaaaaagc ctctatttat tcaaaatgaa gaagaaagag
    16441 aaaaaataag tggaacagaa agaggtacaa tagtccattt agttatggag gttttagact
    16501 taaaaaatgt aagtagtgta aatgatataa aatcacaaat aagaggtttt gtttcaaaag
    16561 gtataataac agaaaaacaa gctagtatag taaatccata taaaatatat aaattttttg
    16621 cctctaacat aggaaaaaga atgttgaatg ctgaaattat aaatagagaa aaatcaattt
    16681 atgcacaagt aaatatgaaa gacatatata tttatgaaaa gcttataaac aatgacgata
    16741 aaaaacttta tgataatgaa agtgtcatgt taagaggtat agttgatgct tattttgaag
    16801 aagacaatca aatagttttg gtggattata aaacagattt tgtaaatgag gaaaatataa
    16861 atcaaataat agagaaatat aaaaaacagt tggatttata tgcagatatt attgaaactt
    16921 taactggtaa gtcagtaaaa gagaaatgta tatatttatt tggagttgat gaagctgttt
    16981 gttattagtt tttatatata aattaaacct aaaagataga ggaaggggaa aaaatgagat
    17041 ttattcatac atcagattgg catctaggga agtccctaga aggccattct agaattgagg
    17101 aacaagcaaa gttttgtgag gaatttataa aaatagtaga atcaaatgaa atagatatgg
    17161 ttataattgc tggagatgta tatgatactt ctaatccacc agcacaagca gaaaaactat
    17221 tttatcagac tgtatcaaga cttgccaata atggtcagag gtgtgtatta ataatttcag
    17281 gaaatcatga taatccagag agactctctg caataacacc tctagcacat gaacagggga
    17341 tacttatata tggttatcca ttaagtgcta cgatagaagc taagtataaa gggtttgaaa
    17401 taacatatgc aactcaggga tgtacaaaac tgaatataaa tggagaaaat attgtggttg
    17461 ctacattacc ttatccaagt gaaaaaagat taaatgaagt tttttcaagt gaagatgagt
    17521 ttgagaaaca aaaaaattat tctgaaaagg taggagatat atttagaagt ttagaagaaa
    17581 attttagaag tgatactata aatatagccg tatcacatat atttgtaata ggtggagaga
    17641 gtactgaatc agaaagacct atacaattag gtggaagttt tttagttgaa agaaaagatt
    17701 tgccagaaaa ggctcaatat actgcactag gtcatttaca taaacaacaa aaagcttccg
    17761 aacgtttaaa tgcatactat tctggttctc cacttcaata tagcaaggat gaaagagcgt
    17821 ataccaaagg ggcatacata gtggatataa aagctggtga aaaaccaata attgaagatg
    17881 tatattttaa taattacaaa cctatagaag tatttaaatg taatggaata gaagaagcac
    17941 tagatatatg tgagcaaaat caagatagag agatttggtc atattttgaa ataaatactg
    18001 atgagataat atcacagaat gaaattaaaa aaatgaagga actattaaaa gacataatag
    18061 aaataaaacc aataataaca tcttgttatg aacaagaaag tgtagatata aaagaaaagt
    18121 ctatggcaga gttgtttaga gagttctatt cttttagtaa aggtgtagag ccaaaaggag
    18181 aacttatgga tttatttcta gatataataa gtgaagaagg tgaatcagca gatgagacca
    18241 attagattag aacttacagg gcttaatagc tatattgata aacaagttat agactttgaa
    18301 aaattaattg aaagaggttt gtttgggata tttggaacta ctggaagtgg aaaatctaca
    18361 atcttagatg caataactat tgctatgtat ggaaatatat ccagaaatac aaaagaatat
    18421 ataaacagtg tgtgcgataa ggcaattata tcatacgagt ttgagatagg aagcaaaaac
    18481 actagaagaa gatacattgt agatagaacc attgctagaa gcaaaacagg aacaaagacc
    18541 tctaatgcta gattaataga agtattgaat gacaataccc aaaatgtttt agctgataaa
    18601 gttgtggaag taaatgaaaa agtagcgcag gtcgtaggat taacggcaaa tgattttact
    18661 aggtcagtag ttttaccaca agacaaattt aatgagtttc taagattatc acgtgcagat
    18721 agaagagaca tgttagagag aatttttaat cttgagaaat atggaagaag tcttggcgaa
    18781 aaagtgaaaa agagaaaaaa tatacagtta caaaatttaa aagatttgaa atcaaaatta
    18841 agtcaatatg atggaattac agaggaagta tataacaata taaaccaaga attaatagag
    18901 ttaaaaaatt tggaaaaaga taagaataat gctttagacc tagctcaaaa atcttatgaa
    18961 gaaagtaaaa cagtatatga agaacaatta aagttagaaa aaaatgaact tagaaaaaat
    19021 gagcttgatt taaaaaatag tgagataaaa gaaaagattg ctcttgtaga aaatgatagt
    19081 aacgctaaaa aggtagaccc atacataagt tcagttcaaa atctagaaaa aaagatagat
    19141 gaagatagct tcgcagtaag taatttagaa aagaaattag caatattaaa tcaggagctt
    19201 gaagttacaa aaaatagata tgaaaaaata aacaaaatta agaatgaaga aatccctaaa
    19261 ttgagtgaag aaaaaataag attgcaacaa gcaataaaat tagaagaaga gttagtttta
    19321 ttagatagag agttaaaaga gctaaaagaa agtggaatta atttaaataa gactaaagtt
    19381 gaattagaaa aagtaaagca ggtgtcagag tccagaaaag atgcagttac taaatctata
    19441 aaagaagttg aaggaaagat tgataaagta aatataagtg cagaattaaa acaaaaaata
    19501 tttctagcat atgaatacga gaaagattac aacaacgtat tggaagaaaa aaatcaaaag
    19561 ctaaataaac tagaagaaat actcaaagag acagaaaata taaatttaaa agttagatat
    19621 attgataaag ataagaatga tgtaaatcgt aatttagaaa atttatcact tcacttggat
    19681 gttcttctta aaaaatgtcc tggtaagagt gctgatttac ttttaaaatc tgaatatgtt
    19741 actgaattaa gaaataaagc aaataatact aaagaaaatg aaattaagaa aagcagtata
    19801 caagatgaat taaagataat acttgaaagt aagtttaata ctgaaaggga agtaaattta
    19861 ctaaatgaaa aacttgaaaa taatagaaag aacagagatg acttagaaaa agaattagaa
    19921 gaactaaagt atttaaattt agcctctgaa cttagacgtg aattaaaaga aaatatgcct
    19981 tgtccagttt gtgggtcaaa acatcatgaa aatcatgata taactaagta tgatgaaaat
    20041 atatcttttg tcaaagaaaa actggagaaa ttagaaaaag aaaaaataag tataagaaac
    20101 aatatagagg aattaaatgc taaagtaagt gggtatttat ctatagaaaa aatgaagact
    20161 aaagaacttg aagatgtaaa aggaaaacta ggggggattc catctagtca attattaaaa
    20221 aaacttgatg aagaacaaag aaaacttgca ttgttaaaat ctaatattca ggagtgggag
    20281 aaagaaaaag agagtactga aaataaagta acattagcta aagaagaaaa aaataaaatt
    20341 gaaaaagaag aattaaaaat aagagagagt ctgaataatt ataagaaatt aacaagagat
    20401 ttaaacatag aaatagaagg tttagaaaat aaatgtaaaa aacttaaaca ggaataccta
    20461 ggattaaaga cgattactaa agtctctaat ctattgtcaa aagtaaaaga aataagggag
    20521 aatgaaaaag aattagaatt actaagtact gggcattcaa atttattaaa aaatagagac
    20581 tcactagata ttaaaataag agaaaatgag agtaaactac atgaaataga gatagaatta
    20641 ataaaggcta gagaattata tgtagaaaag aaattgagta gagataataa gtataaagaa
    20701 gttattagca taacgaaagg tgatttagct aaaaatcttt tacataatgt tgaagaaaat
    20761 atatgtaaga tattagaaca agaagaatca agtaagaaaa aattggaaga gcaaagatta
    20821 gaatatgaaa aaaacattgc tgaaaagcac aatatagatg gtagacttaa aactgctaag
    20881 gaacaatata aagaccaaaa atcaacacta aataaactat tggcagaaaa taaatttgaa
    20941 agtatatatg cagtaaaaag agctttatta gatactgatg cagtaaaaaa attgattgaa
    21001 gaaatactag agcatgaaga agaacaaaag ttattatcat ttaaaataaa atcatcaaaa
    21061 gaaaaattaa atggaagaag cataaagaag gagtactttg aacagttaaa agatgaaatt
    21121 tataatttga aagtagaaat aggaaatata tccaaagata ttggagctaa tcaaaatcag
    21181 ttaataacat taaaagactc tttagataag ataaatgatt ttaataaaca acttaaggta
    21241 gttgaacaca atgtggactt attggaagaa ttagataaat gtgtacaagg aaataaattt
    21301 gtagaatatg tttctacaaa ccaattaaaa tatatagcgt tggaagcatc aaaacgattg
    21361 gatggaataa caaaaggaag atatgcactt gaaattgact caacactaaa ctttgtaatg
    21421 agagataact ttaatggagg agaaagaaga agcattgata ctctatctgg tggagagaca
    21481 ttcttgacat ctctatcatt agcacttgct ctttcatctc aaatacaatt aaagggaagt
    21541 gcaccattag aatttttctt tttagatgaa ggttttggtt cattagatag tgaactttta
    21601 gaaattgtta tagaatcctt ggaaagattg catagtaata atctaagtgt gggtataata
    21661 agtcatgtcg aggaacttaa aaatagagtt cctgttaagc tattagtttc atctagtgag
    21721 gctggaatag gttcaaaagt aaaaattgaa tatagttaga aaatatatgt taattgaata
    21781 tattatctaa tatttccaaa taatatgtaa ttgtgatata ataaaaacta atattaaagt
    21841 tatttataat taatattaat ataaaaacat gtaagtagga gtgtggtaag tgttggaatc
    21901 gcccaataat ttgattcaga ttattttttt aatagtatta cttatagggt ctgcattttt
    21961 ctcagcatct gaaacggcct taatgtcgtt gagtaaaatc agaatcagat atatgcaaga
    22021 tgaaggagtt aaaggagcta agttagtaag ttcattaata gaaaatccaa ataagctttt
    22081 aagttctata ttggttggaa ataacgtcgt aaatatagca gcaacatcca tatcaacatc
    22141 tttgtttata ggattaatgg gagaaaaagg agtggcactt gctacagctg ttatgacagt
    22201 attagtatta atatttggtg agattactcc aaaaacaata gcagcaaata attcagaaaa
    22261 ggtttctcta ttagtatcta aacctataaa agcaattata tttatattaa gaccaatagt
    22321 atggatattt aatataatta caaatattat atttaaatta tttggtataa caaataaagg
    22381 agctaaatca ttcataactg aagaagagct aaaaactatg gtaaatgtaa gtcatgaaga
    22441 aggcgtcctt gaaatggaag agagagaaat cataaataat gtttttgaat ttggagatat
    22501 gcaagctaaa aatgcaatgg tacaaagaat agatatggta gctatagata tggaagatag
    22561 ttatgatgag ataatacagg tatttaaaac tgaaaaatta agtagaatgc ctgtgtatga
    22621 agaaactata gatgatattg taggaatact taatataaaa gatattatat ttttatctga
    22681 tgaagaaata gagtcatttg atattaaaaa ttatatgaga gaaccttttt tcacgtatga
    22741 gttcaaaaag ataacacaac ttcttgaaga gatgaaactt gaaaaaagtc agatggctat
    22801 agttgtagat gagtatggtg gaacatctgg acttttaact atagaagatt tagtagaagt
    22861 cattgttgga gatatagagg atgaatatga tgaagaagag gatgaaatac aagttataaa
    22921 agaagatgag tatattgtag atggaagtac taaaattggt gatgttaatg aacttattgg
    22981 tgtaaacttg gaatctgagg agtttgattc cataggaggt tttataattg gacacctaag
    23041 cagattgcca gaagaaaatg aagtaattga agttgataat ataagatttt gtatagaaag
    23101 tatagaaaaa aatagaatta aaaaaataag aatatataca taatgtaata atgttcttaa
    23161 atttattaga agtgtataaa tataaaagat atcttttata tttatacact tctttttatt
    23221 ttgtattcaa ataaaactag tatgaaatgg acaaaataaa aatataaatt agaagaaagg
    23281 agatttttaa gatgagcata ctagaaaata attttttata caaattaaaa aacaacacta
    23341 tctttttttg tatatataca ttgttattta tttttattta caaagcgttt ccatacatag
    23401 ctccattttt tctaggtgct ataatagcac ttatgattaa tcctatatca caaaagttag
    23461 aaaataagtt tcatataaat aaaggtatct ctactcttgt tctaagtttt cttgcagtgg
    23521 ctatagtcag tacagttact acaataatag taataaattc aatgaaagaa ttaatgggat
    23581 ttttaaataa tatatctgct aatcctgagg atataagtaa tactattatg tattttttaa
    23641 ataaaataaa tgactttatg aaatcatttc aagaaatagc caattttgat gtagaacaat
    23701 tagtaaacaa attcagtggt gaagtaatgc aaattacaaa aaatcttctt actagtatac
    23761 ttggattggc tacttctatt ccatatatta taatatttat aattaccttg tttattgcta
    23821 cgtattttat agcaaaagac cttgataaga ttgaaaatag tttttataat atgtttactg
    23881 ttgatgttag aaagaaggta aaaaacgtaa agaaagaggc agggctttca cttgttggat
    23941 atataagggc ctatacaata cttatggcta taacattttt tgcaatctgg ggaagttttg
    24001 ctttatttgg attgaaatac ggtctaatag tagggtttgt aggagcttta atggatttaa
    24061 ttccattcct aggtataata acaatatatc ttccagtaat tgtttattat tttcttataa
    24121 aaaattattt tatagctata agtatgactg tgatattttt tgttttgtct ttgattagag
    24181 aaatacttga acctaaacta gtatcagtaa atgttggact aaatccatta gctaccctag
    24241 cagcgatttt tattggaatc caagtaaaag gaataattgg agtaattttt tgtttgggtt
    24301 tggtatgtat gcatgatata cttaagaagg tggatatttt ttaattataa taattgatag
    24361 attttttaaa aataaaattt tattcacagg taaataaaaa aatattaatc ttattaagaa
    24421 agagggtata tacgtgaaac aaaaagtagt ggaaagattt ttaaaatatg tatcatttga
    24481 tacaacatct aattctcagt gtgagaactg tccatcttca gaaggtcaaa gagttttagc
    24541 taagtatata gttgaagagc taaaaacaat gggtgttgat gatgtgagtt tagatgaaaa
    24601 tagttatata atggctactt taaaaggaaa tactgatggt gtggatacta taggattcat
    24661 atcacattta gatacaattg aagatgttag tggaaaagat attaaaccaa aaataataga
    24721 aaattatgac ggaaaagaca tagttttaaa tgaagcgtta aatgttatta cgtatgtaaa
    24781 ggattctcca gagttggaag aatttaaagg tgacgattta atagtcactg atggaacaac
    24841 tctacttggg tctgatgata aagctggtat agctgagata gtgactgcaa tagagtatct
    24901 aataaatcat ccagaaatta aacatggaga tataaaaata ggatttacac cagatgaaga
    24961 aattggtaga ggtgctgatt tatttgatgt tgaaaaattt ggagcaaaat atgcatatac
    25021 tttagatgga ggaatagttg gagaacttga atgtgaaaat tttaatgctg caaatgcaac
    25081 tattactata catggtagaa atgttcatcc aggttcagct aaaaataaaa tggtaaatgc
    25141 tatacatata gctgctgaaa tatcagaaat gttcccagca gatgaaagac cagaaacaac
    25201 agaaggatat gaaggatttt ggcatttaaa ttctataggt ggaaatgtcg agaatgtaag
    25261 tatggcttat attattagag accattgtaa agaaaaattt gaaaatagaa aatctattat
    25321 gatagagaat atagaaaaaa taaataagaa atacgataat agagtggaat tggatttaaa
    25381 agactcttat tacaatatga aagaaaagat tgagccagtt atgtttatag ttgatatagc
    25441 taaagaagct atggaggaat taggtataaa accacgttta gttcctgtaa gaggtggtac
    25501 tgatggagca agattatctt ttaatggatt accttgtcca aatatattta ctggtggatt
    25561 aaacttccat gggaaaaatg agtgtatacc agttagttct atggagaaag ctactaaact
    25621 aattgtaaga atagctgaaa aatatgctga aagagtttag ttaaaaagta tttaaaaatt
    25681 aagcatttaa agttataata gctatatcat tctttataag tcaagctgat tataagcttg
    25741 tgttgtactt aaaatggtat agctattttt gtaattattt ttataaaaga taattatttt
    25801 tagtttaggg tatcaataaa aagtatgaat atcaataggt attaacattt aaaaggggga
    25861 attgtattga aaattaaatc taaaaaaata atagcatttg cactttcact tgggattatg
    25921 ttgccaagtt gtgtatatgc agacaatatt agtaaaaatc aaaatgcaca ggtagatatg
    25981 aacaattatc ttcaaggtag aaaatctcca aaggaggaaa aacttattgg tgaagataga
    26041 tttgatacag cgataaaaat atctcaaagt ggttggaata atggttcaga aagggtgttt
    26101 ctagttaact caaattcatt gccagatgca ttggcttcaa ctcctttggc aagtaaattg
    26161 gatgcaccaa tactgcttac aaataaaaat agtataccat ataatgtaac agaggaaata
    26221 aaaaggctta atccagcaga agttatttta attggaagtg aaggagctat ttcatcaagt
    26281 gtaaaagaat ctcttgaaga tatggaagta ttagtcagta gaatcggtgg agcagataga
    26341 gaagaaacat ctttacttct tactagacag ctagatgata ctggtgattt aggtgtctca
    26401 aaagtggcag tggttaatgg gtataatgga ctggcagatg caacttcaat atcaagccca
    26461 gctgcaagtg ataatacagc tataatatat acaggtaagg atagcataag aagtgaggca
    26521 aagaatttta ttacacaaaa ctcaactaag acatacatag taggtgggga gtacagtata
    26581 agtaaaaaac ttgaaggaca gttagtaaac tcagaaagac tagcagggac agatagaaaa
    26641 gatactaatg cgaaagtttt agaaaagttt tatggaaaat caagtaaggt taataatatg
    26701 tattttgcaa aagatggaag tggtagagaa gctgatttag ttgatgggct tgctgctgga
    26761 gtattagcat caaaaacaaa gtcacctgta gtacttgcaa gtggaagttt aagtagtgca
    26821 cagaaaagtt ttataaaaaa agtaaaggct gataaatttg tacaagttgg tggaggtaaa
    26881 aatagtaaac catatgcaga agcattagcc ttacagtaat attgtgtaaa tcaaaattaa
    26941 tatataataa tagcaagtaa accaagttgc actttaatat atataataaa ataagtaaac
    27001 taagttatat ttcagtataa tatataataa aataagtaaa ctaagttata tttcagtata
    27061 atatataatg aaataagtaa actaagttat atttcagtat aatatataat gaaataagta
    27121 aactaaatta tactccaata taatatataa tagaaacaag taaactaagt tatatttcaa
    27181 tatagcatat aataaaacaa gtaaaccaga ttctatttaa ttagaagttt aaggtattgt
    27241 acttaaactt ctaattgaga tagaaataaa atggtttact tgtctttatt atgaatttaa
    27301 taaattaaag cttattttat ttttattaaa aatttactaa tcattgatat ttattatatt
    27361 tccagtattg atgtcaatta agtttatatc aagttcaagc tcatcctcat catcagtttt
    27421 tatgatatct ataattgcga cagaatggct tccatctttt gggatagaag tacttcctgg
    27481 atttattact attaaattat catccatgta tagttttttt acatgagtat gtcctaaaac
    27541 taatatgtca ccacccattt tctttgcttt gtcaataatt tcttcttctg attctatata
    27601 accatgattc aatataattc taatttcacc aaattggctc atgacataag gactctgaat
    27661 aggatgttct ataaccatct ggtcaacatc tgcatcacag ttccctttta caatcacaat
    27721 gttttctaat ttatttaatg tctcaataaa ttttttagga ttatatcctt ctggaatatc
    27781 atttctaggt ccatgatata agacatctcc accatgtaat aaaacatcac aatcagataa
    27841 tacatttaac gctttttcaa agtaaagtaa gctaccatga gtatcactca ttattcctat
    27901 tttcatatta aaaatcctcc taagtacagt ctataaaaat ttttcagata ctctatgcca
    27961 aaactcatag tttgacattc taagtaattt tatttttgca tcagatatac taacttttat
    28021 attttcgatt tgtctaaatc tgtgctcaac tccatcaacg acaatcaata cagaatcttc
    28081 aaatctatat tctggtgcaa tctttataac agattcattt gaacatatta tacttgatgt
    28141 aaagcaccta tatgcattgg tatttatcgg atgtaaaggt gtaatctgca taagttcaag
    28201 atttatatca acaatactac ctccagcaga atagttatag gctgttgaac ctgtggaagt
    28261 agaaataatc ataccatctc cactaaaatt ttgtatatgt ttattatcaa ggcttaaatt
    28321 taggtgtata gtcctagact tgtctcctct tataacaacc tcatttacag caagcatatt
    28381 agaaccacta gtagttgtat atacttccgc attaagaagt gacatttctt gaataatata
    28441 atcttttttt gtataagctt caataaagct atcaatctta tctggtaaaa tatcaggaaa
    28501 aaaccccaga tgacctgtat ttattcccat tatgggaatc tcaggaaaat cgaaatctct
    28561 aactgttctt aaaaaagagc catcaccacc aattgatata ataagctctg tgtctggata
    28621 aatatctgaa tacacttcaa agccagcatt gataagtttt ctagttaaga gttctttagt
    28681 ctcaagggac ttatttaatt ggtttgtatt tatagttata attcttttca tatattcacc
    28741 tcttcatact ttgtattata acatagtttt ataattctta atttataaat ttataaatga
    28801 cctttgtagt gaatgtgtta aaatatgtat aggtgggtat aaaaaaatgc ataagaggtg
    28861 aagatgtgtt tagcataagg aatatcacaa aaaaattagg aaaattcaag ttaaataata
    28921 taaacttaga gttaaaggaa ggggatattg ttgggattat aggaccaaat ggttcgggaa
    28981 aaacgacttt aataaaaatt ataatgggga ttattgatgc agatgaaggt gaaattgaac
    29041 tttgtaatga aactattgaa aattctccaa taagctttaa aaacaatatt ggttttgtat
    29101 atgattcttt acaattttat ccgcatttaa aggttaagga atttagaaaa atagtttctt
    29161 tattttataa gaattttgat agagaaaggt ttgatgaata ccttaataag tttgatatag
    29221 aagaaaatat gcatattgaa aatttatcta aaggtcaatc tgaaaagctt atgttatcaa
    29281 gtgcacttag tcacaatgct aagttattga ttttggatga accaactgct gggatagacc
    29341 caattgtaag aactgaaata atgcagtact tacaagattt tgtgaaaaat ggaagtagta
    29401 gtgtaataat ttctactcat aatactgata atttaattaa aattgctgat tatcttgttt
    29461 ttataaatag aggaaatcag atttttactg ttaagaaaga attaatagaa caagaatata
    29521 agataattag ggcaaataaa gcagagttag aagcaattaa agaaagcata gttggtgtga
    29581 aagagtataa atattataat gaggcacttg ttaaagttgg agatagcttg aaagtaaaaa
    29641 gcctattgat agaaattgat aagcataagg tcaaaaatcc tactatagaa gaactaatgt
    29701 attattatgt aaatgaggtg agatgatgtt caatttaata agaaaagatt taataatagg
    29761 gattagttca gatggtatcc gtaatttaaa gtacatattg ctattttttg tgttttattt
    29821 tttccttaat tcaatttcat attatacagt aagtattgtt gttagttatt tgatatttat
    29881 aaatacgttt gagtgtgatt atgaaaatga ttcaaggatt tttataagga gtatgccagt
    29941 tagtatagaa gatatagttt actcaaaata tttattaggt gtaggattaa taatttctgt
    30001 aacaataatt gtgtccttac taagtaaatt gacatcacta gtgttcttta gaaatatggt
    30061 tttaaatgat gtattttttt ctgtaaatat atttttagca attttgacga ttttactgcc
    30121 tttaattttt aagtttggat atggaaaaat gaaagtttgt ggttttatag taagtatttt
    30181 aatttacttt gtatatggaa gtcttttgaa gatgattagt atgattgtat atcaagtaaa
    30241 gcattttaat tatagtaaag ttggaggagt atatctttca aattatgtaa ctgatatagc
    30301 taatactaag tatataaatt tatatagtat gacattttta acaataataa tttttataat
    30361 atcaatgtat ttttctatta agatttcaaa aaagaataag tttaattatt aaaattttga
    30421 ttaatattat agcacaatag cacaaaatat aaggagacta aaaatgaaga agtttataaa
    30481 agtttcattt tttattttgg ggatttttac actattcata gctataaata aattagtata
    30541 tagagatatg gtaagtgtca aagattatga aataaatcat ttagaggaaa ttgtttttga
    30601 ttttgatagc aggagaagta gagatgttgg tactattgta agatttaaaa taagcaataa
    30661 tagtaaatat agttataaat taaacagtgc taaaatgaag tttgaaaatt gtgtggaaaa
    30721 taaaaaggga atgaataagt gttctgcata tgtaaatgta gatttattta atgaaaaaaa
    30781 ttctataact gaaagaactc tgaaatatgg aataaaacca aataatcaag gttatgttga
    30841 ttttgtaatt ccaaaaggac taaattttga ttataggtac tttaatgaat ctggtatgag
    30901 tgtagagtat aaaggagaat atattgtcaa tattccaatg gcaaaaggac tttatctagt
    30961 agttggaaaa aataatgata catggaatgc taatatcatg gaataatttg aaaaataaat
    31021 caattataga tataattaag aataatatga aatttataaa agttcagact aggagggata
    31081 tttaatgtca ataagtaatg taagagagta ttttaaacaa tttggcaagg aagacagtat
    31141 attagaattt gaacaatcta gtgctactgt ggaacttgca gctgaagcag ctggggttat
    31201 tccagcaaga atagctaaga cactctcatt taaaatagga gatgatgcaa ttttaattgt
    31261 gacagctggt gatgctaaga ttgataataa gaagtataag gctgaattta attgtaaggc
    31321 taaaatgttg acaccagaag aagtcttgga gtttactgga catgctattg gtggagtctg
    31381 tccatttggt ttaaaaaatt ctataaaagt ctatttagat gattcaatga aaagatttga
    31441 tacagtattt cctgcatgtg gcagtagtaa ctctgcaata gaacttacat gtgaagaaat
    31501 ggagaagttt tctaagtgtg aaaaatgggt agatgtttgt aagaattggt aaaaaaatat
    31561 agtaaactat agtaggaatt agtaaaaaac tacctctgta tacaatctat acagaggtag
    31621 tttttttgtg taaatattta taaatctaag aggaaaatct aatttaaact aataatccaa
    31681 aataaagtta aaaaattctg attttttttc gaaacaataa aaaaatgaca aaaaagtgga
    31741 aaaaatgtaa taaatattgt taaaaaaata attagaaatt attgaaaaat tatcctttga
    31801 gtgatactat tatagatgta agatatttaa aaataaaaaa tagtcagata aaaatacgat
    31861 tatttagctc tattaaaata atttttatac gataaaaatc ttctgtacat ggctaaaaaa
    31921 cagatgtaca gacaatattt aatgtttaat ataccctaat ataaatatcg taaacaaatt
    31981 attttatctg taaccagtgt gaaagaaatc ttattctaac ttgaaatttc acaaaattcc
    32041 aaaaagcgag atttttttta agtatagttg attttaaatt aacaatttat gattaaatta
    32101 atgtcataat tggttagtat aatcacatat aaatatagag cgtagtttga ttaaggttat
    32161 aaatttctcg acgtatattc aaatacctta ttatagatgt tgccgagatt ttaattaata
    32221 aatgaaaata aaatatttat aaaatactga ggaggctatt atggatttaa attctaaaaa
    32281 atatcagatg cttaaagagc tatatgtaag cttcgctgaa aatgaagtta aacctttagc
    32341 aacagaactt gatgaagaag aaagatttcc ttatgaaaca gtggaaaaaa tggcaaaagc
    32401 aggaatgatg ggtataccat atccaaaaga atatggtgga gaaggtggag acactgtagg
    32461 atatataatg gcagttgaag aattgtctag agtttgtggt actacaggag ttatattatc
    32521 agctcataca tctcttggct catggcctat atatcaatat ggtaatgaag aacaaaaaca
    32581 aaaattctta agaccactag caagtggaga aaaattagga gcatttggtc ttactgagcc
    32641 taatgctggt acagatgcgt ctggccaaca aacaactgct gttttagacg gggatgaata
    32701 catacttaat ggctcaaaaa tatttataac aaacgcaata gctggtgaca tatatgtagt
    32761 aatggcaatg actgataaat ctaaggggaa caaaggaata tcagcattta tagttgaaaa
    32821 aggaactcct gggtttagct ttggagttaa agaaaagaaa atgggtataa gaggttcagc
    32881 tacgagtgaa ttaatatttg aggattgcag aatacctaaa gaaaatttac ttggaaaaga
    32941 aggtcaagga tttaagatag caatgtctac tcttgatggt ggtagaattg gtatagctgc
    33001 acaagcttta ggtttagcac aaggtgctct tgatgaaact gttaaatatg taaaagaaag
    33061 agtacaattt ggtagaccat tatcaaaatt ccaaaataca caattccaat tagctgatat
    33121 ggaagttaag gtacaagcgg ctagacacct tgtatatcaa gcagctataa ataaagactt
    33181 aggaaaacct tatggagtag aagcagcaat ggcaaaatta tttgcagctg aaacagctat
    33241 ggaagttact acaaaagctg tacaacttca tggaggatat ggatacactc gtgactatcc
    33301 agtagaaaga atgatgagag atgctaagat aactgaaata tatgaaggaa ctagtgaagt
    33361 tcaaagaatg gttatttcag gaaaattatt aaaatagata aatattaaaa tatacacaat
    33421 aggtcgatat taaaatagat atggaggaag gatttatgaa tatagtcgtt tgtataaaac
    33481 aagttccaga tacaacagaa gttaaactag atcctaatac aggtacttta attagagatg
    33541 gagtaccaag tataataaac cctgatgata aagcaggttt agaagaagct ataaaattaa
    33601 aagaagaaat gggtgctcat gtaactgtta taacaatggg acctcctcaa gcagatatgg
    33661 ctttaaaaga agctttagca atgggtgcag atagaggtat attattaaca gatagagcat
    33721 ttgcaggtgc tgatacttgg gcaacttcat cagcattagc aggagcatta aaaaatatag
    33781 attttgatat tataatagct ggaagacagg cgatagatgg agatactgca caagttggac
    33841 ctcaaatagc tgaacattta aatcttccat caataacata tgctgaagaa ataaaaactg
    33901 aaggtgaata tgtattagta aaaagacaat ttgaagattg ttgccatgac ttaaaagtta
    33961 aaatgccatg ccttataaca actcttaaag atatgaacac accaagatac atgaaagttg
    34021 gaagaatata tgatgctttc gaaaatgatg tagtagaaac atggactgta aaagatatag
    34081 aagttgaccc ttctaattta ggtcttaaag gttctccaac tagtgtattt aaatcattta
    34141 caaaatcagt taaaccagct ggtacaatat acaatgaaga tgcgaaaaca tcagctggaa
    34201 ttatcataga taaattaaaa gagaagtata tcatataatt taagggggga taaagaatgg
    34261 gtaacgtttt agtagtaata gaacaaagag aaaatgtaat tcaaactgtt tctttagaat
    34321 tactaggaaa ggctacagaa atagcaaaag attatgatac aaaagtttct gcattacttt
    34381 taggtagtaa ggtagaaggt ttaatagata cattagcaca ctatggtgca gatgaggtaa
    34441 tagtagtaga tgatgaagct ttagcagtgt atacaactga accatataca aaagcagctt
    34501 atgaagcaat aaaagcagct gaccctatag ttgtattatt tggtgcaact tcaataggta
    34561 gagatttagc gcctagagtt tctgctagaa tacatacagg tcttactgct gactgtacag
    34621 gtcttgcagt agctgaagat acaaaattat tattaatgac aagacctgcc tttggtggaa
    34681 atataatggc aacaatagtt tgtaaagatt tcagacctca aatgtctaca gttagaccag
    34741 gggttatgaa gaaaaatgaa cctgatgaaa ctaaagaagc tgtaattaac cgtttcaagg
    34801 tagaatttaa tgatgctgat aaattagttc aagttgtaca agtaataaaa gaagctaaaa
    34861 aacaagttaa aatagaagat gctaagatat tagtttctgc tggacgtgga atgggtggaa
    34921 aagaaaactt agacatactt tatgaattag ctgaaattat aggtggagaa gtttctggct
    34981 ctcgtgccac tatagatgca ggttggttag ataaagcaag acaagttggt caaactggta
    35041 aaactgtaag accagacctt tatatagcat gtggtatatc tggagcaata caacatatag
    35101 ctggtatgga agatgctgag tttatagttg ctataaataa aaatccagaa gctccaatat
    35161 ttaaatatgc tgatgttggt atagttggag atgttcataa agtgcttcca gaacttatca
    35221 gtcagttaag tgttgcaaaa gaaaaaggtg aagttttagc taactaattt cttggggagg
    35281 gtattatgag tacaagtgat gttaaagttt atgagaatgt agctgttgaa gtagatggaa
    35341 atatatgtac agtgaaaatg aatagaccta aagcccttaa tgcaataaat tcaaagactt
    35401 tagaagaact ttatgaagta tttgtagata ttaataatga tgaaactatt gatgttgtaa
    35461 tattgacagg ggaaggaaag gcatttgtag ctggagcaga tattgcatac atgaaagatt
    35521 tagatgctgt agctgctaaa gattttagta tcttaggagc aaaagctttt ggagaaatag
    35581 aaaatagtaa aaaagtagtg atagctgctg taaacggatt tgctttaggt ggaggatgtg
    35641 aacttgcaat ggcatgtgat ataagaattg catctgctaa agctaaattt ggtcagccag
    35701 aagtaactct tggaataact ccaggatatg gaggaactca aaggcttaca agattggttg
    35761 gaatggcaaa agcaaaagaa ttaatcttta caggtcaagt tataaaagct gatgaagctg
    35821 aaaaaatagg gctagtaaat agagtcgttg agccagacat tttaatagaa gaagttgaga
    35881 aattagctaa gataatagct aaaaatgctc agcttgcagt tagatactct aaagaagcaa
    35941 tacaacttgg tgctcaaact gatataaata ctggaataga tatagaatct aatttatttg
    36001 gtctttgttt ttcaactaaa gaccaaaaag aaggaatgtc agctttcgtt gaaaagagag
    36061 aagctaactt tataaaaggg taaaaatcta attaaaaata tatttgctgt taactagatt
    36121 aaatagtatt ttaatctagt taacagaata taaatactaa aataacagga ggttataact
    36181 atgaaattag ctgtaatagg tagtggaact atgggaagtg gtattgtaca aacttttgca
    36241 agttgtggac atgatgtatg tttaaagagt agaactcaag gtgctataga taaatgttta
    36301 gctttattag ataaaaattt aactaagtta gttactaagg gaaaaatgga tgaagctaca
    36361 aaagcagaaa tattaagtca tgttagttca actactaact atgaagattt aaaagatatg
    36421 gatttaataa tagaagcatc tgtagaagac atgaatataa agaaagatgt tttcaagtta
    36481 ctagatgaat tatgtaaaga agatactatc ttggcaacaa atacttcatc attatctata
    36541 acagaaatag cttcttctac taagagacca gataaagtta taggaatgca tttctttaat
    36601 ccagttccta tgatgaaatt agttgaagtt ataagtggtc agttaacatc aaaagttact
    36661 tttgatacag tatttgaatt atctaagagt atcaataaag taccagtaga tgtatctgaa
    36721 tctcctggat ttgtagtaaa tagaatactt atacctatga taaatgaagc tgttggtata
    36781 tatgcagatg gtgttgcaag taaagaagaa atagatgaag ctatgaaatt aggagcaaac
    36841 catccaatgg gaccactagc attaggtgat ttaattggat tagatgttgt tttagctata
    36901 atgaacgttt tatatactga gtttggagat actaaatata gacctcatcc acttttagct
    36961 aaaatggtta gagctaatca attaggaaga aaaactaaga taggattcta tgattataat
    37021 aaataagaat ttgggaatta aaagtttaaa taaaattgtt taaaaaacaa tttcggatat
    37081 atgaaaaatc taatttaatg ggggtaatga atatgagaga agtagtaatt gccagtgcag
    37141 ctagaacagc agtaggaagt tttggaggag catttaaatc agtttcagcg gtagagttag
    37201 gggtaacagc agctaaagaa gctataaaaa gagctaacat aactccagat atgatagatg
    37261 aatctctttt agggggagta cttacagcag gtcttggaca aaatatagca agacaaatag
    37321 cattaggagc aggaatacca gtagaaaaac cagctatgac tataaatata gtttgtggtt
    37381 ctggattaag atctgtttca atggcatctc aacttatagc attaggtgat gctgatataa
    37441 tgttagttgg tggagctgaa aacatgagta tgtctcctta tttagtacca agtgcgagat
    37501 atggtgcaag aatgggtgat gctgcttttg ttgattcaat gataaaagat ggattatcag
    37561 acatatttaa taactatcac atgggtatta ctgctgaaaa catagcagag caatggaata
    37621 taactagaga agaacaagat gaattagctc ttgcaagtca aaataaagct gaaaaagctc
    37681 aagctgaagg aaaatttgat gaagaaatag ttcctgttgt tataaaagga agaaaaggtg
    37741 acactgtagt agataaagat gaatatatta agcctggcac tacaatggag aaacttgcta
    37801 agttaagacc tgcatttaaa aaagatggaa cagttactgc tggtaatgca tcaggaataa
    37861 atgatggtgc tgctatgcta gtagtaatgg ctaaagaaaa agctgaagaa ctaggaatag
    37921 agcctcttgc aactatagtt tcttatggaa cagctggtgt tgaccctaaa ataatgggat
    37981 atggaccagt tccagcaact aaaaaagctt tagaagctgc taatatgact attgaagata
    38041 tagatttagt tgaagctaat gaggcatttg ctgcccaatc tgtagctgta ataagagact
    38101 taaatataga tatgaacaaa gttaatgtta atggtggagc aatagctata ggacatccaa
    38161 taggatgctc aggagcaaga atacttacta cacttttata tgaaatgaag agaagagatg
    38221 ctaaaactgg tcttgctaca ctttgtatag gtggaggaat gggaactact ttaatagtta
    38281 agagatagtt ttagattata atatttacaa attaaatatt taattatgaa tttaacctgt
    38341 aagaataact atttgttatt cttacaggtt tttatagtta aaaataatta ttatctatta
    38401 aacaaaaata gtgtaaaata tataatatca tgattttgaa gatataaaaa agtaggaaga
    38461 tataaaagaa agtaggtaaa agtttgttta aaaaagagaa tcaaagatat aatcttatat
    38521 cgtatacaaa tgaagaagaa atgactttaa aagaagtttt attggacaag ctaaatttct
    38581 cagttaggtc attatcaaaa atgaagaggg aaaagagtgt tttagtaaat ggagtatata
    38641 aaaaaccgag tttaaaggtg tatagtggtg atttaataga agtaaaaata gacgaggaaa
    38701 aagcaaattt tgaacctcaa gatttaaatt tacagataat ttatgatgat tttgatataa
    38761 ttatggtgaa taaacctccg tttatggtag ttcacccaac aaaaagccac tatgataaaa
    38821 caatagcaaa tggtattagt tactatatag ataatcaaaa agaaaatgta aaaataagat
    38881 ttgtaaatag gttagatatg aatacttcag ggttagttat agtagcaaaa aatgcttatg
    38941 cacatcatac tttgtctaca gcaatgagtg aaaataaagt tgaaaaaaag tatataacag
    39001 tagttgatgg aattataaaa gaaaatgagg gaactataga tgagccaatt tatagaccta
    39061 cagaagattc aataaagagg ataatagatg aaagaggaca gtcatctgtt actcactata
    39121 aagtaataga aagactagaa aatgcaactg tattagaagt aagcttagaa actggtagaa
    39181 cacatcaaat aagagtacat atggctcata taggtcatgg aataataggt gatgagttgt
    39241 atggttatgt agatgaagat ctaataaata ggcaagcact tcatgcatat aagctagagt
    39301 ttgaacaacc aagaacaaaa gaaaaattga aatttaaagc agatatacca gaggatatga
    39361 aagagttaat atcgaaatta agataatggg gtgatatata tgataataca taaatttata
    39421 atacatgttt tggacaaaaa tagtgatgtt ccaatattaa atgactttga aggcaaagtt
    39481 aatcaagaag tagatggttt tttccagaaa gctataaaaa gaattgcaaa agatgaggat
    39541 ttaagaaaag gtgtttttaa agattataat gacaatttaa ttaaaaactg ttgtgaacaa
    39601 ataatatatg atgaaagtac ttttttgaaa aattctaaag aaattgcatc ttacttgttt
    39661 gatgttatga aaattaatgc tgcactagaa tcttgtgatt tggcaatttg cttatacact
    39721 attaaagatg aaaagagtgt agcaatactg aaattagatt ataaaaagtt gtacactcat
    39781 tcaattgaat ttgtggatga taaatttaat attcaaatgg tttcaaatga aattggtatc
    39841 ccagagactt taagacaaaa gcaaggagct ttgattagtc taagtggtat aaatgatgag
    39901 tttcatctaa ggcttttaga taaggatgct gaaaaagaag ggtcagaatc taagtttgta
    39961 acagaatttt taaatgctaa aaaaatagat gatgataagt acaagaccaa ggtatttaaa
    40021 aatacagctg aaaattggat aaccaatgct cttagtaatg atataaagca agctgaagat
    40081 gtaagaagta tattaaatta tacactgaag gaaaaacatg aagttgatat aaatgacttt
    40141 gttgataatt caattaaaga tgatgagtta aaggatagct ttaaagagca tatggaagaa
    40201 aaaggtcttg acgaaagttt tagtatagat aaaaaatggg ttgagaaaaa gcttaaaaaa
    40261 agaagtataa aaacggataa tggttttgac ataaaaggga atctaactga ttttgaagac
    40321 ccaatgaagt atactgtaaa acaaaatcaa gatggaacta tagatataat aataaagaat
    40381 gttacgtttt atgaagaaaa gtaatttata tacttagtat ataaattaaa tataagagcg
    40441 tgtattttat atattgtaaa taaatgtaat ctagtctgtg cgaactctaa tataatttat
    40501 tatgtagaag tttacacaga ctatttatat ttgtagacaa aacgatacta tttgttttct
    40561 tcgatatatt tacatatatc accaatacat ttaaagtttt cagcttcctc gtctggtatt
    40621 tctattccaa attcatcttc aagggccatt ataatttcaa cagcatctaa tgaatcagct
    40681 tctaagtcgt ccattaaaga tgcttccata gttatctcat ctaaattgtc tacccctaat
    40741 tgttctgcta ttatttcttt tattttctca aacattttaa gcctcctaaa gcagttttaa
    40801 ttaattttaa tgttagttta atataatatc aagaattttt caatatggaa tctataaaaa
    40861 ataataaaat tttataaatg tagtaataaa gtattatttg atgaataaac tttattgata
    40921 acaaatataa cttaggagga aatgctatga aatatgtagg actattacta acttcagtag
    40981 gaatgttttt acttatagca gtaaattttt attataattc aataacttta gatatgcaac
    41041 gtatagagga ttatgtaatg gagaccaatt taatccttga agatgtagct gaaaaggaga
    41101 gttatgtatc taatgaaaaa gaagattaca tatcaaggtt aatgcatgta aagaaaggaa
    41161 tagaaaattc aaaaacatcc ttcttgatag aaagatataa ggagtacaaa ataaaatcaa
    41221 tagaaagttt aatctatact atatcagagg agaaaaaaga ttatctggat gaagttgata
    41281 gatacaataa acttggtgaa aaagaaataa ataaactaat caataaaaac tttttagaag
    41341 taacttatct gtctattact acatatattt aattaaagag acaaaactta gtctcttaat
    41401 gattcaagga ggattagtta tgacaaaatt agaagacaat atggaacgtt tctttggagg
    41461 atgcgaagga ttttttggga ataaaatgtt gataataata gttatagtat tcttactatt
    41521 atgcacagac attttagaag acttattatg cgatgacaat atatggatat gggttatatt
    41581 aatagtattg ttattattta acttcgatga tggttgttgt tgctaaaaaa tattgattat
    41641 taaataggta aaaccagtaa cttatacaag ttatggtttt acctttttta gttcaaatta
    41701 aaaaatttaa aaaaatagta aaaatacatt agcaaaatgg aaaccaaatg catagtatat
    41761 gttaggagcg aaaagctcaa caaaatatca acaggaggta acgtataatg ttagatagat
    41821 tctttggaga agaaggatgt tttggtggag gaggatggtg gataatagta ctattcttcc
    41881 tattcttagc ttttggagat agctgggcag aatttgacat aatggcatgg ataccattcc
    41941 taatagtttt attaatactt tgctgctgtg gtggatgctt agaataagaa cacagttatt
    42001 aaaaaaagga gggctttgtt atgttagata gattttttgg agaagaagga tgctttggtg
    42061 gaggaggatg gtggataata gtactattct tcctattctt agcttttgaa gattgctgga
    42121 gagacattga cataatgtca tggatacctt tcttaatatt attgctaata acttgttcat
    42181 gtggtggatt ctttgatggt gaagtaggtt gcggctgcta atacttaaat cattagaata
    42241 aaaaaatgct ggtattttat accagcattt ttttatttta ttttttaata tgatttaaat
    42301 taagaatgaa tattattaaa tttgttgaat atagggtata atataaaata taatgtattt
    42361 aaatgtactt gcttttatgg taaaataaaa acttatataa atgtagttaa aataggaacc
    42421 ttcaaaaatt tggttcagtt ttagataaat ttagtaaaat aaggaggatg aagatgaaag
    42481 gcaatataac gataaaagat gttgctaaac aagcaggagt gtcaatatct actgtatcta
    42541 gagttataaa tgattcaaaa cctgtaactg atgaagtcaa acaaaaagtt ttagaggtta
    42601 taaaagagac tggatatata ccaaatccac ttgctagaag cttagtaaca aagaagagtc
    42661 aattaatagg ggtaatagtt ccagaagttt cagattcttt tgttaatgag gtgttaaatg
    42721 ggatagaaga ggttgctaaa atgtatgact atgatattct tttagcgaat acatactctg
    42781 ataaggaaca agaacttaag agtataaatc tattgagagc aaaacaagtg gaaggtatag
    42841 ttatgatttc atggatagtt gaacaagaac atatcaacta tatacaaaat tgtggaatac
    42901 cagcgacata tataagtaaa actgctagaa attatgatat atatacagta agtactagca
    42961 acgaagaagc tacttttgat atgacagagc atcttataaa gaaaggtcat gaaaagatag
    43021 cttttataat gactagtaaa gatgatactg ttttagaaat ggaaagactt gctggttatg
    43081 agaaagcact ttcaaataac aatatagaat tagacaagag tttgattaag tatggtggaa
    43141 ctgattatga gagtggatac aatagtatga aagaactatt agatgatgga ataatacctc
    43201 atgcggcttt tgtaacaggt gatgaggctg ccataggtgc tataaatgct atatgtgatg
    43261 ctggatataa ggttccagaa gacatatcag ttgcaggatt taatgatgtt aagatagcta
    43321 gaatgtatag acctaaactt actacagtat atcaacctct atacgatatg ggagcagtag
    43381 caataagaat ggttataaaa ttaataaata aggaattaat tgaaaataag aaaatagagt
    43441 taccttatag aattgttgat agagaaagtg ttacagaaag aaaaaaataa aactattaaa
    43501 atcaatcagg tagtgcctta ggcactacct gattttttat gtcaataata tcaaatttaa
    43561 taatagatta actaaaaata attatctaat tgcttaaata gtttattttt atctattcat
    43621 gaggattaga ctttttagtt ttcttaaata aacttttaga ttttttttgt tgactacctg
    43681 gtgtattttt tggtgcaggt gaatttgact tacctttagt aggtttagcc ttcttagttt
    43741 tagctggttt agtatctctt tggttttctg catctgagat tttttccatt atattatcca
    43801 gttttttgcg ttgattttca tctaaaaatg ctttgaattt tgatactact tcatctctgc
    43861 catctagatt cttacctatt tttataagtt cctccataag ttcattttct gattttcctt
    43921 tgtaactatc agccatcttt tctattttat ccttgtcaat atttttttgt ttagccattt
    43981 tttctaatga ctctgtatct aattttttca taaaaaaacc cctttctata aatatatatt
    44041 gaattatatt catactattt atatatagaa ataatattga agtggtgaat tgtgagtgat
    44101 atataatata aataaaaatt cttatagata atatatatgc actgagcttt aaaaatggaa
    44161 cattaaaata tgaaaaacat actttaatat agggcaatta tataatataa gggggaattg
    44221 tcttgaataa cttactattt ttgattggag tgattgcatt gagtaatggt aatatctcta
    44281 tatttgatga taaaaataaa tcaaaaggaa ataatagagt tagaaaaaac aaaaaaaatg
    44341 caaatgataa actttcacag tctacacatg gcaatttaag gtttgatgca aatgatataa
    44401 aaagaggttt aaggctcatg gatttaagtg aagaagattt agaaatggga atggaaataa
    44461 taacaagaac taaaaaatac atgtcaagag atgaaagaaa aatactaata aaaatagaaa
    44521 gtgttttaga tttagttaga ggaataaaaa aattaaataa tatagatatg gtagatacag
    44581 aagatgaaac ggattttttc agaaaaatgg atagtgatga taaaaagaat atgatgataa
    44641 aggaaattat agatgtattc ccagaaaaaa gaaaaaattc agttgaaaaa gctataggaa
    44701 tgaaaaagaa gatagattta tttgcagaat tatttttacc agatgacttt ggtgaaggtg
    44761 gatttagttt gagctctttg gcaaatataa acaatcttgg tagtatgaat aatctcaaat
    44821 tgttaggaag tcttttaaga ggtgatgata gtaataatga tgatgaagac aataatgatg
    44881 agttaaatta tgaagacgaa gaattagatt gtgaagacaa agaattggat gatgatgagt
    44941 taacagatga aggtgaaatg gaggataatg aagatgaatt agtagaagat aagaacacag
    45001 gctatgaaaa tatagaaaat gatgaagata tagtatacga tgaggaacta tacaacatta
    45061 atgagcaaga atccgaatac aattataatg aaaaaaatac taaaactaga gctaagaaaa
    45121 aacgataatt aactaaatac ataaagaaaa aaggaagaaa aagtaatgat agaataagat
    45181 tatctcaatt actatataaa accactttaa aaaattcaaa atttattata taataataat
    45241 atgaaatcct gaaacatacg ataaggcttt tttaaattca acctacaaat gaaatacggg
    45301 agaccgtgtc tggtaaatta taacatgcct agttagtttg gacgttaaag gttactggca
    45361 agtcacccac ctgggagtgc ctagggtgtg aatttactta gccaccggtg tttcgggaca
    45421 aaaaaagtgc tactatttca aatagtagta ctttttttat taatatgcat ttttctacta
    45481 aatacgccta attattgata aattcaaaaa gcaagtaaca attaagatta taaaagcata
    45541 gtattaatta ggcttcaaaa agccaaagac ttaataagaa tcgcttacag ggagggcaat
    45601 gaaaaatgca agattataaa aaaaataaaa gaagaatgat gaatcagcca atgtctacaa
    45661 tgaatgaaga agaagtgtat acagatgaaa taaattcaga agacatgaga ggttttaaaa
    45721 aatcacacca tcataatgga tgtaatactg ataataagtg tgagtgccat gatgattgca
    45781 atccatgcaa cccatgtaat ccatgtaaac ctaacccatg caatccatgc aaacctaatc
    45841 catgtgatga caattgtgga tgccatgaca attgtaaatg tgattgtgaa ccatgtgaaa
    45901 tggattcaga tgaatgtttt gaaaacaaat gtggaccaga atgctgtaat cctatatctc
    45961 caagaaactt ctctgtatca aatgcagtgc catttgcaat agaggctaat agaatatttg
    46021 atactatgca attccaaaca tttacagatg caacaggacc aaatggagag ccattaactt
    46081 ttgaaacaga agtagtagaa gtatttggtt cagttccaag tgcaggtcaa gcaagtgtaa
    46141 ctatagaaaa aatatgctta agtaatgatg gaatcgttat agacacagga atgacaactt
    46201 tagaagattt cgatttagac ccattaggag atatagtagg aagaaactgt gaaacaactt
    46261 ttgaatttgc agtttgtgga gaaagaaact ctgagtgctg tagacaagga aaaggcaaat
    46321 cagtagctta taaacaaaga ggattaactg tagcagttcg taatttagta ctagagctaa
    46381 gaggtagatg tggatgtaca gagttcgttg cattagcttt cccagcagtt agagcaggag
    46441 gtggatgtaa gagaagagtt gattatgtag aatttacttt taacacactt tcagcaccaa
    46501 tatgcttgcc agctgacgga agagctgtta ctttaagaca agaatatcaa actaacttaa
    46561 ctgtagattg tataggaaaa tctatattaa aattagaatg caacgaatgt tgtgaacctt
    46621 tctatgaatt aattatacca aatgatatag atttagtact ttgcttacaa gaaacagtta
    46681 gcacattaat aagtgaacaa atagtagttt tagcatcacc aaatccaatc caaccaagac
    46741 ttgttgatac tttctctaaa gtatgtgatt tttcgcaatg tggacctaat catggaagtg
    46801 gaaagccaag ttgccacaga tagataggta gatatataga cagtttaaat tataaataaa
    46861 aatcatctaa ggaaggctac caaagtgtat aatttacatt ggtagccttc acgtttttat
    46921 aactagcgta tagattttag tgatttaaaa agcactatag tatgtaatag acaagtaaag
    46981 attgatacta tcgtcattgt gtatatgtat gcataaatat taagtcctgg aattggaaga
    47041 aatacatata aagctattag ttgaattaac atgccagtaa tagtatttat acttgaagct
    47101 aattcttttc ttattgaatg taaaatgcca gatagagttt gatttaggga cataaatagt
    47161 ggaactaaaa acatagcttt tagatattct cctgcaagtg tatttttaaa tactaatata
    47221 cataaatctt ttccaaagaa ataaaaaaat attgatgata gtatgcctac aaataaagta
    47281 agaagtatgg agtatttgat ttttttaatt acactcttac gctttcttag agccatttct
    47341 tgtgaaatag ttggtattaa atttacaata agcgctgaac caacagtaaa aggtaaaaat
    47401 ataaaaggca ttaccatccc actgacaata ccatacatac ttaaagattg ttgataagtc
    47461 attcctgata atgctaatct tgatggtatc atcatagaac ttatagattg caaaagtatg
    47521 tttgacattc tattacaagt tatgggaata gacattttta atgtttccat agaagaatta
    47581 taaaaatctt ttatgcttat aatataccta ttgtcaaatg atgaatctcg ccataagcaa
    47641 ataagcataa atataatatt actcaactca ccaatcgata tacctaatag agctatataa
    47701 caattcatag atttattatt tatgtacata acaagtaaaa aaacaaataa tattttacca
    47761 atttgttcaa tgatttgtcc aatagcaggg atttttacat tctttatgcc atagtaatat
    47821 cctcttagta cgtttgaaag agttattata actatagcag gacaaacagc tagtataaat
    47881 agatttaatt tagcatcttt taaaaattta agtgataaaa aagaactatt gaaagatgca
    47941 actatagata taattagtgc tacgaaaaat gatatatata aagttgatat aaataaagca
    48001 ttagtattgt gtctatcgtt taaagctttt ctctttgcaa ctagacaact aagtgcagta
    48061 ggtatacctg ttgttgtaac agctaagcaa atcatcaaaa agttaaaaat catatgatag
    48121 atacctaaac ctgtttcacc tagtgctctt gataagaata ttttatataa aaaaccaaat
    48181 attcttacaa taaaattgga tataaataaa ataactgttg atagtactaa ataaggtact
    48241 ttcaaaaaaa tcacctcctt atcttttaaa tatattcaca aggaggtgta aaaatttata
    48301 attttataaa ttctggtttc aatttattaa atttagatac atatttaaat cccatatttt
    48361 ttagtaatga atatatgtag tcaaactcac atgcaacttg acttatatga tgtgaatctg
    48421 aacctgtggt tatgatttcc cctcccaagt ctttgtacat ttgaagtata tacttagatg
    48481 gggttaggtc tggaagatta tatctataac aagaggtatt tatctcgata cctttgccat
    48541 cataaatagc ttgtttaaga gtttcttcaa ttatatcaga aaatagtcta tcatctaaaa
    48601 tagtgtcata aggtgcatac cttttaatca aatctaaatg acctaagaca gagtaatctt
    48661 tataattctt aacaatatta tataaataaa gatagtaatt ttcataaact tcatgttgag
    48721 ttttatcttt aaaataatta ccaaggtata agtccattgt atctatagca tggatagaac
    48781 atattataaa gtccaatgga tattgatgtg cttccttttt gtatgtatcc attaattgag
    48841 tttgaactcc aaattcaatt ccttttttta ttgatatttt atctttatat ttgctttgaa
    48901 gagtctctaa actcttaaaa taatcttcgt agacaattga aaaagaatca tcagcatata
    48961 catcatagtc aacatggtct gtgaaacaaa tttcctccaa accgagttca atagattttt
    49021 ttaccatttc ttccattgta gattttccgt ctgtagagaa acttgagtgc atgtgatagt
    49081 cgtaaaacat aaatatttcc cctttttata aaaattttgg tattatatat acatactaaa
    49141 taatatcaaa tatacataaa agcatcaata aaatataaat acaatgagcg gtgataaatt
    49201 tggaaaaata cagaatagat ttaaatgaga aaaaatcaac taaatatata cagatattta
    49261 atcatataaa agaattgata ataaataaag agttagtaga acatgaaaaa ttgcctccaa
    49321 taagaaaact atcaaatttt ttacaagtaa ataacactac tatagttaag gtatacgagc
    49381 ttttagaaaa tgaaggatat gtatataaaa ttatagggag tggtactttt gtatcaagtt
    49441 taaattctta taaaagcggt atagataaca ggaaaaataa gattattgtg caaagagaag
    49501 atttaattca ttttgacaat gggaatccat ctaatgatat gtttcctatc gattcattta
    49561 aaaatgctgt aaatatggca ttatctaaag atggtagttc aatatttgaa tatgatgaag
    49621 gtcttggctc tgaagaatta agagaaaaaa tggtagagta tctaagtgat ggaaatataa
    49681 aaactactaa ggaaaatatt caaataatat caggtgctca acaaggtata gatatagttt
    49741 gtaaaggact tataagttat tcagatgttg tttttatgga agaaccttct tacaatggag
    49801 caattgaagt gtttaaaagt agaggtgcaa aaataatatc tatacctatg ttagatgatg
    49861 gaattgatat aggtatttta aaattaaagt tggaaaaaat aaaaccaaga cttatataca
    49921 ttatgcctaa ttttcaaaat ccaactggaa tatcttactc aacatataaa aaaaagaaat
    49981 tgatagaatt ggcagaagaa catgattttt atataataga agatgatttt ataagtgatt
    50041 ttgtttttga atcaaaggac aatagaacaa ttagaagtta tgatgataaa aatagagtag
    50101 tatatataaa aagcttttca aaaatactta tgccaggtct taggatagga attgtagaaa
    50161 tgccaaatga gttgttaaaa aaagttttat gggctaaata ttcatcagat atatcaacac
    50221 caggtttaat tcaaaaatca atgtattact atatgaataa ttttgattgg aagaattatt
    50281 tgagtcatat agagaagata tatactgata agtataaatt ggcaaaaaac ttgattaatg
    50341 acaaattgag tggtaaatta aaagttagaa aatcttgtgg aggaataaac ttttttttag
    50401 aattaccaag aggatataca tctcaagcat ttacaaattt tatgttaaac aaaggagtgt
    50461 caatgcttcc agggacttat ttttttgaca atctagtgga tgatagattc tttaggataa
    50521 atatagctcg tccaagcatg gaagaactag aaaagggaat atctataata agtgataata
    50581 tagatgagtt tttttgtgaa tataaaaaca agttagatat aaaaagcaat aaattatttt
    50641 attaaataaa tagaggtttt ttaggaggaa aaaatgtttg acaagaagaa attagatagg
    50701 attaatgaat tagcaaagaa aaataaagag ggaatccttt ctgctgatga aatcaaagaa
    50761 agagaaattt taaggaaaga atatttagaa aactttagag cccactttag atcaagacta
    50821 gatagtgtca aagtagtttc accagaagaa tatgagcaat acatgaaaaa caataaaaat
    50881 tagaacttag taggaggaaa atatgaactt aaagtacgaa tttaagaatg cttgggattt
    50941 tgaaagaaaa gaaaatacta ttgaacaaat tatgcaatat tctagcaatt atatggagtt
    51001 tttaagtaag tcaaagactg aaagactttc agtaaaagaa attataaaat tggctaaaga
    51061 aaataactat atttcaatag atgaagctat ggaaaaagga agcataagtt gtggtgataa
    51121 aatttatgtt ataaataaag agaaggcagt agcacttttt gtaataggta aaaattatat
    51181 agaaaaaggt atgaagatta taggaagcca tatagattcg ccaagattag atttaaaacc
    51241 aaatccactg tatcaagaga gtaatctagg tttttttaag actcattatt atggtggaat
    51301 aaaaaaatac caatggacgg ctattccact tgctttacat ggtatagtta tattaaatga
    51361 tggaacaaaa gtggacatat ctattgggga agaagatagt gacccagtat tttgtgtaac
    51421 tgatttattg attcatttgg ctggagacca aatgcaaaag aaactatcag aaggaattag
    51481 tggagaagct ttaaatatat taattgggaa tatgccttta gaagatgaag aaaaagaacc
    51541 tataacagca aatatattaa agattttaaa tgagaaatac aatatagttg aagaagattt
    51601 attaagtgct gaaattgaag tagttccagc tggtaaggct agagatttag ggcttgatag
    51661 gtctatggtg ttgggatatg ggcatgatga tagggtatgt tcatatgctg ctgtaaaagc
    51721 tatactagaa actgaacaac cagaatttac ttcagttgca ttatgtgtag ataaagaaga
    51781 aattggttct aaagggaata caggtatgca ctcaaagttt tttgaaaata ctgtggctga
    51841 actgattgct ttagaaggag attattgtga tattaaagta agaagagctt tagcaaatag
    51901 taaggtatta tcagctgatg tttctgctgg atatgaccca aattttggag aagcatatga
    51961 aaagagaaat tcggcatata tgggaaatgg agtagtttta actaagtata caggttcaag
    52021 aggaaagagt ggatgtaatg atgctaatgc tgaatttatg tcagaagtaa agagaatttt
    52081 taataaagga aatgtagtat ggcaaactgc tgaacttgga aaagtagacc aaggaggagg
    52141 cggaactata gcccatatat tggcaaatca aggtgcagag gttatagact gtggtgttgg
    52201 agttttaaat atgcatgcac cacatgagat tgtctctaaa gtagacatat atgaaatgta
    52261 taagggatat aaggcatttt ttaatataaa tttataagta aaaatataaa tgtaataagt
    52321 gaataaaggc tgttgtataa acaatttaat ctgttgtaca acagtcttat ttttatgtaa
    52381 aaatagcaat ttgtcacact agagaaaata aaagaaaata ctgtcaaatt aaaaattatt
    52441 ttaaaaaaaa ttgacaacga tttcatcttg ttataatatg taataaagaa cttgttatat
    52501 aatgttataa aaatgttaca tagggaggtg agcaaaatgg atgaaaagag acaaaaaaaa
    52561 gaaatggatt tagaagtaaa ttcctttgtt cctttatatc aacaactata tgacaacata
    52621 aaaaaacaaa tagcatctgg catatataaa ccaggagata aacttccatc tgaaggagac
    52681 ttatgtaaag aatttaatat aagtcgtata actgtgagaa atacgacttt tttatataaa
    52741 atagcaaaat aacagtgttt gagcaaaaaa aaagaatgtt ttttatcgtt ttgccacctg
    52801 tttgccacca taactttttt cggtggcaaa ttattgtaaa atgccctcca aaatatctat
    52861 tgtttcactt tccattttac ttgtaacatg tgaatatgta tccatagtgg ttgataattg
    52921 actatgacct aatctttgtt gtatatattt tacattagct ccattttcta ataataatgt
    52981 ggcatgtgta tgtcgcaagc aatgaaaatt aaagttaata tttagtttct tgttaatagt
    53041 tcttatagca gcgtcaatat tgttgtgatt tacaaatgag ccatcttttt ttctacaaac
    53101 ccaatcatac tcagtttctt tataccattt tccaatttta attttttgtt ttttttgatt
    53161 caatttttcc tcttttaata ttctagacaa agtatcacct attttaatat ctcttattga
    53221 tgtttttgtc ttaggtgatg ctaattcaaa ttctgaaact tttctcttta ttaaattttt
    53281 tctaactttg attatattat tatctaaatc aacattatcc caacaaagac ctaatatttc
    53341 tccttttctc atgcctgtat gaaaccctat aagtagagga atatagatat ttgtattttt
    53401 aggatatatt tctagtattt tattgaactc atctagtgtt atagtcttgt tatctgactc
    53461 attttttacc tttaaaacat tttttggtat actggcatat tgaacaggat tttccttaat
    53521 gagtttgtaa gggtaaacag cagattttaa agcagcattt aatacaacat aaatcgcttt
    53581 taaaactcct tttgtgtagt gtttttcttc tccgttttgt gtgtatgtct cttttgattt
    53641 attatttaaa aattcttgaa taatagctgg atttatagat tttagcttac atttaccaag
    53701 tctaggttct atatgatttt caattaaatt tctataactt tcctgagtat tgtatttgca
    53761 attaagaagt acatactctt tgtaccaaaa gttaagatag tctgataaac tcatatttgt
    53821 ttcatcaaac actataccag cattttcata ttcatttatt gcatcacgga gcgatttttc
    53881 agcttctttc ttagtgtttc caccaactct ttctaccttt tttctcttgc catctactat
    53941 acctgcatca aagtagtaat accacttctt tccacgtttt cttacgccgc ctttcataaa
    54001 atttctcctc tcaaaagctt tttttatgta attatataat aacatatatc aatttaaata
    54061 aaataaataa aaaagactat aagaaacaaa gttttatgtt tataattaat agtctttttt
    54121 atttagatac atatttaatg ttttttatca cgtgattcca gcactttttc tgccaaataa
    54181 acaactattt tttcatactc aatatcagtt tctaaagaaa agtcaacaat agcaggtatc
    54241 gtcatatctc ctgcatattt attacctaac caattttcaa ttaattccaa ttcttctttg
    54301 cttaattcaa attttttctt tttattaaaa cttaagttca atttattcac ctcaaataat
    54361 attatatatt aaaaatagta tttgatagaa acattcgaat tatttatgta attttctttt
    54421 tttaatatat tcatcagcaa aataatttac taaatatttt tcttccaatc ctaaagctat
    54481 ttctaattca ataagaatag ggatagttaa atctttatcc tcattatttt ccaacctaga
    54541 aatttgactt ctgtggcaac caactctttt tgctaactct atttgtgtta atttcttctt
    54601 ttttcgtaac tcttttaaca tatatttaac ctacctttta gataatttta tatatgttag
    54661 tttgtgtaat ttcttgtaat aaatgtgcaa tattcgcaca ctttttgttg gaaatttgtg
    54721 ctagaatgta gttaagaaat aactttatct agataaagca aaaataatag aagctataaa
    54781 atataataat attttacagt tattttatag ttttaagctt tgaaaaagag gtggttgtaa
    54841 ctatttttaa gaacgtatgt ttcgtggaat taataaataa aatattttat aggggatgat
    54901 atatttgaat aagacgaaat attatgatat tttaaagtta aacttattaa tgaaaaagtt
    54961 gaaagaattg gataaaaata aaatcaatga atataaaata aaagtgaaag aaatacataa
    55021 aatcaataaa aaagaggaat gattcctctt ttttattata ttcattttca gaaataaact
    55081 attttttatt tttttcgtct agtaaaaata attctgcaac ttttaatgct ttttctcttg
    55141 cgtctgggct tagctcgcta aatatattaa aaacttcttt catatcttcg tcaagataca
    55201 tattctcaat aagctccttt tctgttttaa aattttcagc atcataatct ttttcgtttt
    55261 tatttataaa taagctattt ctaacatcag ttcttcctaa taaataatct gtagacacat
    55321 caaaatagtt tgcatattct tctattgtac ttttcttagg ttctcttaaa ccattttcta
    55381 tccttgatag tgtagatttg tttatatgta aatcctcgct taatttgtct agcgagatgc
    55441 ctttttcttc tctcaattct tttatcctat tcaatttgca caaccccttt ttatattaat
    55501 tccaaaatag caacttttat ttatattata gcaacaaaat taattattac aatttttttt
    55561 gctaaaaaag caacaaaagt attgactata atcacaaaac ttgatattat ataaatatga
    55621 agttgccaaa atagcaaaaa ggaagtgatt taatgtactt aaatagatta gaaggattga
    55681 tgaaggaaaa tagacacacc caaaaaaatg tggcagatat attaggtctt agctcatatg
    55741 gttttagatt aaaattaaaa ggaaaaaacg aatttaaagc aagtgaaata aaaaagatat
    55801 ctaaattata taatgtatct gcggattatt ttttttcaga tgaagttgct aaaatagcaa
    55861 taaaagaaga aaggggcaat aataatgaag aatctaacca taatcaagca aaataatcaa
    55921 tttttagttg aaagtagaga agtagcagaa ttaatagaaa agaagcacga taatttatta
    55981 agagatataa gaggatacaa gaagatttta gaggactcat caaatttgag gagtcaagat
    56041 ttctttatag aaagtactta tataaatact caaaataaaa tccaaccttg ctacttatta
    56101 actaaaaaag gttgcgatat ggtagctaat aaaatgacag gagaaaaagg gattatattt
    56161 acagcaattt atgtaactaa gtttgaagaa atggagcaag agttaaaaga acaacaacct
    56221 aaattaccaa ctacatataa agaagcactg caacagttat taatcgaagt tgaagaaaaa
    56281 gaacaactac aattagaaaa tcaagaaaag gataaggtaa tccagttaca acaaccaaaa
    56341 gtactgtttg ctgattcggt agcgtcttct gacaattcaa tcctagttgg agaattagca
    56401 aaattgctta gacaaaatgg aattgataca ggacaaaata gattatttga ctggttaaga
    56461 aataatggtt acttaataaa acgtaaaggt gaggattaca atacaccaac tcaaaaaagt
    56521 gtagatttag gagttataga aacaaaagaa ggtacaagag tacatccaga tggtcataca
    56581 agtattacta aaacacctaa gattactggt aagggacaaa tatacttcat taataaattt
    56641 aaaagtagca aacaattatc aatgttaagt taaaacatga cagtaccttg aaaactaaat
    56701 acagaatatt caaaagaggt gattagatgc aaagagagca aacaacaata cgcctgccta
    56761 gagaacttaa agacaagctt ctaaaacagg caaaagttaa aggatataca ttaaaagata
    56821 tggtgatttt tattctaaag gattatcttc aaaatacttc tcaagaataa attcaatttc
    56881 tctacctata gaacgtttat ctttttgtgc aagttgttca attttttcaa aaagaagttt
    56941 attaattctt aatgtaaatc ttttatcctc ttcacgagta taaatatctt tattagacat
    57001 atttatcatt ccttacataa aatttgacgt ctttatgaca ctttaataat aaaataatta
    57061 atacagaaag tcaataaaaa tgcttgacgt caaatgtatg acatgttatt attaaaacaa
    57121 gaaaggagtt gacgtcaaat atatgacaaa cgaaagagtt agatttacat ttagattacc
    57181 agcaccattg cttgaaaaaa ttaaaaatag agcatcaata gaaggaagct ctatgaactc
    57241 attaatacta cacatacttt ggaattatat acaagaaatt gaaaacgagg aggttggtaa
    57301 gtatgaataa tatacaaata tttaaaaatt ataatttcgg agagataaga actatcgaaa
    57361 ttgatggtaa accgtatttt gtagcaacag atatagcaaa agctcttggt tactctaata
    57421 ctagggatgc agttaagaaa cattgtaagt gggtagcgaa atgcgacata cctcatccgc
    57481 aaagcgattc taaagcttta aaggtaaatg taataccaga aggtgatatg tatagattaa
    57541 ttacaaatag tgaattacca aacgcagaaa aatttgagag ttgggtattt gatgaagtgc
    57601 ttccaactat tcgacaaact ggtcaatacc aagcacaaca gcacgtaata acagaactta
    57661 caggaactat aggagattta aaaggaacaa taaaagaata taaaaagttg tgtaagataa
    57721 cttgttctaa gaaacaacag tattctaaat acataaagaa tagactggat atagacaaag
    57781 ctaataaaga atacaaccaa gtgaaagcga gattatttct aattcttgga gttgagaagt
    57841 gggaagatat agattttgat acatctaata atttaataca gattatagat gattgcataa
    57901 gagttataaa gtcagagaga ccatacaagc aattaagtta ctttgaaaac taaatacaga
    57961 atattttaaa aaggagtgtg taattaaatg aaaatttcat ttgaaagtgt agtgaacaat
    58021 gtaaataatg aaacggaatt aatattatca aaagaagagt tacaaatagc taaaaggata
    58081 cttaatacat tgaatgaaaa tgaacaaagt atcctttcct caaaagatat tttagatttt
    58141 tgcaaagaag ctcttaaata taatttagta cctacatttg tttaaagaca ctgaggccat
    58201 cgcctttaga aaaactatta ttgacttctg aaagtttcaa aaagatttca tggtaatgtt
    58261 ttaaaagttc ctcttcagaa gaacttttaa aatcatattt ttccttaaga atttctaaag
    58321 taagagtatg taatatatct ttactgaact gcataatatc accaactttc ataaaaagat
    58381 ataggatata tcctacaaat atagtatatc aaaggaggaa aataatggca attaatgaca
    58441 acataaataa aattttaaaa gatagagatt taaaagcatg gaaattagca aaagaaatag
    58501 gtgtagattc agggaattta tatgcaattt taagaggaga aaataaaaat ccaactatag
    58561 atacattaat aaaaatagcc gactatttag acattacatt agatgaacta gttggaagat
    58621 aaaaattaaa tacagaatat tttgaaaagg agtgagtaaa ttgggcaata tatctaattt
    58681 caatttagat aaacaagaag ataaaagttt taatgaccta gataatatat caatttgttt
    58741 ttcagaaggt atccgtaaag ttgtagaaat gaatttaaac aactataaaa ataaaatctc
    58801 aaagtactta aatgaaactt cgaaaataga attattagaa ccaaaagaac taacaattgt
    58861 tataagtaaa ggttatcccg attatcttat gtctgttgaa gaagcaagta aaagattgaa
    58921 aatagataaa gtatttggat atgagttaat aaaaaatggg cttttgaagt cagttgatat
    58981 aggggcaact aaagtttcta gttatgaatt agatgatttt ataactagaa atcaaggaaa
    59041 aaacatcaaa gaaatgctta gagaaatgaa agaaattaga gagggggtga tttagttgaa
    59101 tgtaagagta ctaatagctt atgtacagtt ttgcaatgat aagcaaataa aagcaagttt
    59161 tgaaggtctt agaaaataca acagagatat agagttagtt aacttgtatt taccaagtaa
    59221 attaaaaatt aagggggatt aatcatgaaa agtttaacta tagtaagaaa tgcagtagag
    59281 caacaactaa atagagctaa tttagaaata aataaaaatg aggaacttta tacaaaactt
    59341 agaaaaaaag aaaaaagaga tgtattagat gaaatagagt taagtaatgc tttaagagaa
    59401 aaaagtgtaa atgaaagatt aaaaatattt gctgagtcat tactaaaaat tatagataca
    59461 caaattgaaa taaaagaata tgaagaaagc gaggattaca agatatttga attaatttca
    59521 gaagaaattg aaagagatag acctatagat attcagatat agaaaagagc cattaggagt
    59581 ggctcgattc caaaataata taaaatataa gctaattata gca
//
LOCUS       DAJMZY010000010        58753 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.010, whole genome shotgun sequence.
ACCESSION   DAJMZY010000010 DAJMZY010000000
VERSION     DAJMZY010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 58753)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 58753)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..58753
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.010"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            200..835
                     /locus_tag="OE968_000608"
     CDS             200..835
                     /locus_tag="OE968_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HCP7217923.1"
                     /translation="MIAVKDENNVVNLRGELDNKLEFSHEIFGEKFYNMKIKINRLSD
                     SFDILPMTVSERLLQDIDLDKQNLVNVVGQLRSYNKTLNNKNRLVLTVFVREIKSIDE
                     ENKDPNSIFLDGYVCKEPVYRKTPLGREITDLLVAINRPYNKSDYIPSIVWGRNAKFA
                     KNLKVGDRIQLWGRVQSREYEKKIDENNVVKKMAYEVSISKIKKLDENNNE"
     gene            1019..1588
                     /locus_tag="OE968_000609"
     CDS             1019..1588
                     /locus_tag="OE968_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HCP7217924.1"
                     /translation="MKSILCQINKQPVKAKYTSDELECFLDTIEYNVGDKILLVGHIG
                     NLGKRLRGLGTSVTILENSNYEDVCYSLVYNENCNVVKGKLEFLPFDDNQFNKIIIVD
                     QFNVITDCEKASSEIQRVLKGNGEVILEDLNLKNLKVKLNYLKHKFCGSVAKIHYPHE
                     VFNIFSRLNFDGMIKESNKLKYIYVGKRR"
     gene            1666..1803
                     /locus_tag="OE968_000610"
     CDS             1666..1803
                     /locus_tag="OE968_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7217925.1"
                     /translation="MEINYELIIIVMLFVILMSIQFTLNKIYLILKEIRQILMLKKNK
                     E"
     gene            1800..3575
                     /locus_tag="OE968_000611"
     CDS             1800..3575
                     /locus_tag="OE968_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HCP7217926.1"
                     /translation="MMIMIGLEYIKSDIQNIAEAIVSVLNIDVTIVNKELFRIAGTGV
                     YIDKIGEKVDKYTAFKKSLTEQITILIDDPKSSDICRECYKSGACVEFAEVCCPIICD
                     GVSHGVIGLIAFTKEQAQIIENNKSGLINFLGKMADLISNKLKAQIKTYELELEKKKL
                     ETLLNNMDKAVVSIDVDGKIDKYNSKFKELFNIKDSITGKNIFVELDFIKKPSINNFK
                     KDKSCSFFYKRYGYDSKGIYNINKIVLKNELKGYVIDFIDKRDAIKNYNKMNKDYRIK
                     LENIIGESVAIRNSKKEALIASKSTSTVLITGESGTGKELFARAIHNHSNRVDNPFIA
                     VNCAAIPDNLLESELFGYEEGAFTGAKKGGKLGMFEVAHKGSIFLDEIGDMSLHLQSK
                     LLRVLQEKELNKIGSKSNVSIDVRIIAATNKDLEKMVQNGTFREDLYYRLNVIPIKLP
                     SLRERKEDIPLIIKHMVKEYSKKLDKNVIDIDSRVVDAMMEYKWPGNIRELQNIIEYS
                     VNMSSSSIITMNVIPQKIKNTSVEELEVKSDRIIPLDELEKIEIIKALNKYKDYKKDK
                     ELTAKALGISRATLYRKIEKYNIIS"
     gene            4000..5307
                     /locus_tag="OE968_000612"
     CDS             4000..5307
                     /locus_tag="OE968_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine dehydratase subunit alpha family protein"
                     /protein_id="HCP7217927.1"
                     /translation="MRDIRKELVEMLKAEVKPAVGCTEPVALALACAKAKELLGEEIV
                     ENRMLVSPSIYKNGMCVGIPGTERLGLKIAAALGIVGGHSENGLSVLETLTKEEVKIA
                     EDYMDNTPLSITPADTREKVFIEVVLKGKNHIAKVRIRTKHDNFTFLEKDGEVLLDNE
                     PKVSASNDAAEKAESLMDTVTIQELIKNVEGIDFKDIEFLLDGVKMNEEMAEYGLKQK
                     TGIGVGYGIKKSIEEGLLGNDVINYAMMLTAGASDARMAGVKMPVMSSNGSGNHGLTA
                     ILPIVAYNKKFPQSDERLAKALAISHLVTGYIKNYTGRLSAVCGCGVAASTGATAGIS
                     WLMNGTEKQIEGAIENMIADLSGMICDGAKAGCALKLSSAASAAIQSAIIAKQDCFVP
                     PLNGIVGSSVEQSIQNLGRVSDKGMSITDEIILNVMNDMNKVD"
     gene            5635..6174
                     /gene="hpt"
                     /locus_tag="OE968_000613"
     CDS             5635..6174
                     /gene="hpt"
                     /locus_tag="OE968_000613"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HCP7217928.1"
                     /translation="MDIETKKWEVLYSEEKIKDKLRELGAIIEKDYKDKNLMVVSLLK
                     GSFIFCADLVRNINLPLRVNFMTTSSYGNNEESTGKVKVVSDVTTDIAGYDVLVVDDI
                     TDSALTMDFVLKHLKAKNPASLKCCVLLDKPSRRKVDLVPDYCGFEIEDKFVVGYGFD
                     FGDYYRNVPYIFNVTDEDR"
     gene            6552..8228
                     /gene="bclA2"
                     /locus_tag="OE968_000614"
     CDS             6552..8228
                     /gene="bclA2"
                     /locus_tag="OE968_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like exosporium glycoprotein BclA2"
                     /protein_id="HCP7217929.1"
                     /translation="MSDISGPSLYQDVGPTGPTGATGPTGPTGPRGVTGATGANGITG
                     PTGNTGATGANGITGPTGNMGATGPNGTTGSTGPTGNTGATGANGITGPTGNTGATGA
                     NGITGPTGNKGATGANGITGSTGPTGNTGATGANGITGPTGNTGATGATGPTGLTGAT
                     GATGANGITGPTGNTGATGANGVTGATGPTGNTGATGPTGSIGATGATGTTGATGPIG
                     ATGATGADGEVGPTGAVGATGPDGLVGPTGPTGPTGATGANGLVGPTGPTGATGANGL
                     VGPTGATGATGVAGAIGPTGAVGATGPTGADGAVGPTGATGATGANGATGPTGAVGAT
                     GANGVAGPIGPTGPTGENGVAGATGATGATGANGATGPTGAVGATGANGVAGAIGPTG
                     PTGANGATGATGATGATGANGATGPTGATGATGVLAANNAQFTVSSSSLVNNTLVTFN
                     SSFINGTNITFPTSSTINLAVGGIYNVSFGIRATLSLAGFMSITTNFNGVTQNNFIAK
                     AVNTLTSSDVSVSLSFLVDARAAAVTLSFTFGSGTTGTSAAGYVSVYRIQ"
     gene            complement(8582..9337)
                     /locus_tag="OE968_000615"
     CDS             complement(8582..9337)
                     /locus_tag="OE968_000615"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HCP7217930.1"
                     /translation="MLKVIISGYNGTMGRVLAECVKKDNELELVCGVARSADEKGHHS
                     DTKLYKTMTDVTEKTDVIIDFSHHDTLEPILSYALKNNTPVVLATTGYDENDLNKIEE
                     ASKNIPILLSSNTSLGVNILIKLVKDASKMLEGFDIEIIEKHHNRKEDAPSGTATMIA
                     NAIREVLPESENTHGRYGRDCKRKPNEIGIHSIRGGNIISDHDVVFAGDNEVLTLSHH
                     SQSDEVFANGSIVAAKFLIGKQSGLYKMSDILG"
     gene            9777..10766
                     /locus_tag="OE968_000616"
     CDS             9777..10766
                     /locus_tag="OE968_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HCP7217931.1"
                     /translation="MLKEEKTYQEKDAKVFNGVAALIMILLFLVVSIGIMVFGIVKLD
                     SGFTGIGSLMLILGLVFIVVDFILFFGLKMINPKEAIVLVLFGNYYGTIKKEGYYWVN
                     PFCSAINPAVSRINVSKSSSDEKVDISTNSRGKKVSLKTMTLNNEKQKVNDLLGNPII
                     IGVVVIWKVIDATKAVFNVDNYNTFLSIQCDSTIRNVSRLYPYDVSEDGDEKSLRGSS
                     QEIADRLKDELQSRVDIAGIEVCEVRITHLSYAPEIAAAMLQRQQAEAIIAARKKIVE
                     GAVSMVEMALTNLSENNVVTLDEERKAAMVSNLLVVLCGNKDAQPVVNSSSIY"
     gene            complement(11218..11934)
                     /gene="dapD"
                     /locus_tag="OE968_000617"
     CDS             complement(11218..11934)
                     /gene="dapD"
                     /locus_tag="OE968_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HCP7217932.1"
                     /translation="MVNLNDAYEIARYIKEVKKKTPVKVYVNTNSLHFQSTDKFKVFG
                     SNGSYIFVGDYEDIMEVLDKHGNDITDTHVEYDRRNSAIPLKNTLSEHARIEPGAIIR
                     DMVTIEKNAVVMMGAVINIGAVIGEGSMVDMNAVIGARGTLGKNVHLGAGAVVAGVLE
                     PPSATPVIVEDDVLIGANAVILEGVRIGKGAVVAAGAVVTTDVEAGAVVAGSPAKVIK
                     MKDEKTADKTKLMEDLRNLD"
     gene            complement(12158..12907)
                     /locus_tag="OE968_000618"
     CDS             complement(12158..12907)
                     /locus_tag="OE968_000618"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HCP7217933.1"
                     /translation="MLKVIATGYDGKMGKILADTIREDNELELVCVAARGLDSYEGDL
                     KIYEDMSTIVEEADVVIDFSHHSNLDNILSYVLKTKTPLVIATTGYNDDEMNKIREAA
                     KVIPVFQSYNMSLGVNVLVKLVKDAAKLLEGFDIEIIEKHHNRKVDAPSGTAVMIANA
                     IKEVLPNVENNYGRYGRSAKRQPNEVGIHAIRGGNIVGEHDALFAGDNEVLTISHQAQ
                     SRGIFASGSIAAAKYLVKQKPGFYNMDSMLG"
     gene            complement(12974..13861)
                     /locus_tag="OE968_000619"
     CDS             complement(12974..13861)
                     /locus_tag="OE968_000619"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HCP7217934.1"
                     /translation="MIFKGSAVALVTPFTKDNKVDFDKLGELVEYQIANGTDAIVSCG
                     TTGEANTMTDEEQLATIKYVVEKVNKRVPVIAGSGSNDTMHSVNLSQEAEKLGVDALL
                     IITPYYNKANKAGLKRHFETIANSVKLPIILYNVPGRTCVNISPSLIVELAKIDNIVA
                     VKEASGDLGQVAEIASLVPDDFAIYSGNDDTILPLLSLGGQGVISVLANVCPQETHDL
                     VAKFFEGDIEGSRKLQLGMDALIAALFIEVNPIPVKTAMNLLGFNVGDLRLPLAEMDP
                     ANLEVLKKELVNFGLKVNA"
     gene            complement(13978..14979)
                     /locus_tag="OE968_000620"
     CDS             complement(13978..14979)
                     /locus_tag="OE968_000620"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HCP7217935.1"
                     /translation="MKKVNVAIIGATGMVGRTFLKVLEERNFPIENLFLFSSSKSAGS
                     KVMFCGKEYIVEELKETSFTDRGIQIALFSAGGSISEKYAPIAASNGILVVDNSSQWR
                     MNPDVPLVVPEVNPEAIKNHKGIIANPNCSTIQAMVPLKALDDKYKIKRVVYSTYQAV
                     SGSGVKGVEDLEKGMNGNPTGFYPHQISYNCLPHIDSFTENGYTKEEMKMVNETMKIL
                     DNYDLKITATTVRVPVKNGHSESINVEFNNPFELDDLVKTLEEAPGVVVVDNPAKNEY
                     PTAVEFDDRDEVFVGRIRRDFSVDNGVNLWVVADNIRKGAATNAIQIAEMALSYDLV"
     gene            complement(15404..16285)
                     /locus_tag="OE968_000621"
     CDS             complement(15404..16285)
                     /locus_tag="OE968_000621"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HCP7217936.1"
                     /translation="MLFKGSAVALVTPFTEDNNVNFEKLGELIEYHIENGTDALVVCG
                     TTGEATTMSESEIFAVIKYTVEKVNKRIPVIAGTGSNNTMLSVHMSQEAEKLGVDGLL
                     IITPYYNKTNEKGLKLHFETIANSVKLPIILYNVPGRTKVNIKPSVVAELAKIDNIVA
                     VKEASGDLAQVAEIAKLVPKDFAIYSGNDDTILPLLSLGGSGIISVLANICPKETHDL
                     VTKFFEGDIEGSKKLQLDMDALIAALFIEVNPVPVKTAMNILGFNVGDLRLPLAEMEE
                     TNLNVLKQELTNFGFKF"
     gene            16608..17801
                     /locus_tag="OE968_000622"
     CDS             16608..17801
                     /locus_tag="OE968_000622"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase"
                     /protein_id="HCP7217937.1"
                     /translation="MDTLKELFKIGSGPSSSHTMGPQRAAERFKNENPDAESFRAILY
                     GSLAATGKGHLTDYIIEKTIAPKKVEIVWEEDIIKDFHPNGMKFEALDKDKNVTAEWT
                     VYSVGGGTIAEEGQRNSKSNSIYHLDTMDEIVKWCKENNKTLVDFVLECEPKDIKDYI
                     KTIKDAMRKSIDDGLSTDEIIPGKLLLKRRASTFYNAYKKDKSFSTLVYAYALAASEQ
                     NASGNIIVTAPTCGSAGVIPGIFFAMQDFYNYDDEKIIEALLVAGIIGNIIKTNASIS
                     GAEVGCQGEVGAACSMAAAAVAYLKGGTIDHIEYAAEIALEHHLGMTCDPVYGYVQIP
                     CIERNAMAAQRAYDAANYALLTDGSHSVSLDQVVETMKETGIDMMDKYKETAKGGLAK
                     HFFSC"
     gene            18007..19125
                     /locus_tag="OE968_000623"
     CDS             18007..19125
                     /locus_tag="OE968_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HCP7217938.1"
                     /translation="MREASYLQEQLYKHRKSLNPIAEIGRKEYKTSKYIRDYLDKLGI
                     EYEVYLETGIVGVIEGKRPKKDIAFRADIDGLHSEEGVKHLCGHDGHATILLGLIEYL
                     NDNKEDLNDNIVFIFQPAEEGPGGAKALIDEGVLRKYNIDEIYGLHIYPELPEGYVGT
                     REGYFMAQIGDIDIEIVSKSGHGAMPQNGIDGIVIASNFVSSLQTIVSRNISPIDNAV
                     LTIGRIEGGARRNIIAENIKMEGTMRCFSPEVYEKMKLRVRELARGFELAYNCKVNIN
                     IIDDYIAVKNDKDLYQEFVEAIGSDTVVELEPLMISEDFSYYQKEVPGLFFMLGSRNE
                     EKGFVNGLHNINFNFDEKICVNALNVYSKLLKYKEAID"
     gene            19256..19501
                     /locus_tag="OE968_000624"
     CDS             19256..19501
                     /locus_tag="OE968_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small, acid-soluble spore protein, alpha/beta
                     type"
                     /protein_id="HCP7217939.1"
                     /translation="MKEKVQREKKITNGKNTKILTNDDIMKYEIASELGLMDKVGERG
                     WAGLTAKEAGRIGGMLTSRKKRLKKIVEEQNKKDESI"
     gene            19488..20234
                     /locus_tag="OE968_000625"
     CDS             19488..20234
                     /locus_tag="OE968_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HCP7217940.1"
                     /translation="MSQYSDFAFVYDELMNEVDYNGWVKYIEDIIDSEGVKVKNILEL
                     ACGTGNLTIPLTKKNYDIAGIDISDEMLSVAREKSEKEGVELVLLQQDISELDFEISD
                     LDCVLCACDGFNYITYDDDLENVFSKTYELLKKDGIFIFDISSFYKLANILGNNMYGE
                     NREDIAYMWQNYFDEEENLIEMELTFFIKDECGKFERFEEIHQQRAYTEDEIVDMLEK
                     SGFKDIKYYGDFTFDKPSEESQRIFFVCKK"
     gene            20519..21394
                     /gene="hslO"
                     /locus_tag="OE968_000626"
     CDS             20519..21394
                     /gene="hslO"
                     /locus_tag="OE968_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HCP7217941.1"
                     /translation="MRDYVLRATSGNGQVRAFVATTRNTVEEARRLHETTKVATAALG
                     RTLTATSIMGLMMKNDSDKLTVIIKGGGPIGTIIATSDSKGMVKGYVGNPQVEVEDYP
                     NGKLNVAAAVGTEGVVKVIKDLGLREPYNGTYPLVSGEIAEDFTYYFAVSEQTPSVVA
                     LGVLTKEDEVEFAGGFIVQLMPDAEEETIAKLEENVAKLPSITNMLKEGKSPEDILNI
                     VLDGLEPKILDTCEVGFMCECSKERVKTALVAIGKKSLAQIIEEDKKAEVGCQFCNKK
                     YMYSEEELLEILKEM"
     gene            21785..22585
                     /locus_tag="OE968_000627"
     CDS             21785..22585
                     /locus_tag="OE968_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HCP7217942.1"
                     /translation="MESKTKYIGISILILLMIFLIAKNFNGKLEIPIPESNSRKFKSA
                     AVFYPQHQDDEVLWGGSAIVDAIKQCGVDNVYVVLVSDGSGVNVFKANTKFRNLTRKQ
                     KEELRNNEFKSALRELGVKPQNVIILADIDKKEGTHYELMEKTILDFEHKFKGNVTHI
                     AHHYKYDDHIMHRKNGEVLKKLKREGKIKDDLYFVKPKYVKYIPRNERAIYKAMDFDD
                     YNKVKSACYEYKVVNSKRKMYGIGYISAHSYFEHLLNDPELTSVLSED"
     gene            23112..25352
                     /locus_tag="OE968_000628"
     CDS             23112..25352
                     /locus_tag="OE968_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HCP7217943.1"
                     /translation="MNNEFIILKGCKENNLNNISLKIPKRKITIFTGVSGSGKSSIVF
                     ETIAKESQRQLNERFSTFVRSFLPKYGEVKADCIENLSTPIIIDQSRLGGNSRSTLGT
                     ITDVNSFLRALYSRFGSEYIGNANMFSFNNIDGMCPHCHGLGKKLVPNMNQILDMNKS
                     LNEGAILLSGFGVGSWHWNIFAESGFFDINKRICDYSEVELEKFLHGKAEKIKIENAG
                     QTNMTYEGLMVKFNRLYLSREGEISEATKKKLSKLLIEDRCPICDGRRLNERVYRSLI
                     NGYNIADLTSMQIDELAEVIKSIDEPEAQPLIKGIIEKLNSIIDIGLGYLTLDRETSS
                     LSGGESQRIKMVKYLNSNLVDLMYIFDEPSVGLHPKDVYKLNNLLKKLRDKGNTIIVV
                     EHDPDVIKIADHIVDVGPKAGKYGGEVVYEGSYENLLTSGTLTGNALSKFLPIKESVR
                     EHSGYLEVKNCNKNNLKNVSIKIPKGVLTLVTGVAGAGKSTLIKDEFLKQNPSAVLID
                     QSPVSANSRSSLATYSGIMNNIRSIFSKTNGVNASLFSSNSEGACDNCKGSGIVEMNL
                     AFMESIKSTCNVCEGKKFKKEVLEYRFQGKNIIEVLEMSVLEAIEFFNLKQIKTKLQC
                     IEKMGIGYLTLGQTLDTLSGGECQRLKLASELNKESSVYILDEPTTGLHMADIENFIS
                     IIEEIVDNGNTVIIIEHNIDVIKRADWIIELGPEGGTKGGRVIFEGIPKQLCNNKISL
                     TAKYIV"
     gene            25766..27301
                     /locus_tag="OE968_000629"
     CDS             25766..27301
                     /locus_tag="OE968_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HCP7217944.1"
                     /translation="MINDILTLLSERSDFFIKLSIEHLMISIISIIIAIVLGGIIGII
                     VSEFHNSSKPILGTINFLYTIPSISMLGFLIPFSGIGNTTAVIALTIYALLPMVRNTY
                     TGITNVDKNILEAARGMGSTDFQILYKIKLPLALPVIMSGIRNMVIMTIALAGIASFI
                     GAGGLGVAIYRGITTNNTIMTITGSILIALLALIFDFILGLVEKFFQRKRKKKNRKKV
                     FAILGSLILIATIFTSYLFNPSKTQTIHIATKPMTEQYILGEMLDILIEKNTGLNVEI
                     TQGVGGGTSNIQPAMENGEFDIYPEYTGTGWNMVLKKNELYTESMFSKLQSEYKTKLK
                     MQWTGMYGFSNSYALAVRKEVADKYNLKNITDLKDVSSKLTFGAEYDFYEREDGYTPL
                     CNTYGLNFKDTVDLDIGLKYQAINEGKIDVMPIFTTDGQYSVSDVVVLKDDKNFYPSY
                     QCGNVVRLEVLEENPELSKVFKMVGDILTDKEMAKMNYDVENNNLEPREVAREFLNKK
                     GLL"
     gene            27317..28078
                     /locus_tag="OE968_000630"
     CDS             27317..28078
                     /locus_tag="OE968_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCP7217945.1"
                     /translation="MTPIIQFKNIKKQYNDKTIIDNLNLDIEKGEFLTVIGSSGSGKT
                     TLLKMINGLILPDGGNILINQTDIKNEDLIKLRRRIGYCVQGSVLFPHMTVEENISYV
                     PNLLSKKNKLEVKSAVNKWMEIVGLPNDMKVRYPSELSGGQQQRVGIARALASSPEIL
                     LMDEPFGAVDEITRKQLQKEIKEIHKKTGVTIIFITHDIYEALILGTKTLVLNHGVVQ
                     QYDTPENILNTPANQFVDQLLNIRKSIIDDDNLKE"
     gene            28416..29285
                     /locus_tag="OE968_000631"
     CDS             28416..29285
                     /locus_tag="OE968_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HCP7217946.1"
                     /translation="MDNNLITIEKTLDYIEKHLLDEMLDLNVISKEIGYSKYHLHRMF
                     TSVVGFSVHNYIQRRRLTEAARMLIFTEKPIIEIALISGYDTQRSFSRGFKKMFKRSP
                     NFFRRHQDFLPLQLKFDIHNRKKLRGDMVLDVKKVNCADINIVGYSGKVRKGFHIIGK
                     CWRDLHKNKEMIENKVDLGFLIGVSDYSNFKEIENTPTFTYIAGAQVATFGKLPNGME
                     KFVLPKSNYIVFTFIGKNEDSMQNVVEYIYQEWFPNSSCQFNENNLYDFVKYGEKTDE
                     NGLSEIQFWVPII"
     gene            29614..29865
                     /locus_tag="OE968_000632"
     CDS             29614..29865
                     /locus_tag="OE968_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3781 domain-containing protein"
                     /protein_id="HCP7217947.1"
                     /translation="MNVENELLKNLDRLHTTELGVVRIKKNLSLETNDVVNWCKTKIE
                     SPNAIINRKGKNWYISVYDCIITVNAHSYTIITAHKEKK"
     gene            29977..30756
                     /locus_tag="OE968_000633"
     CDS             29977..30756
                     /locus_tag="OE968_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HCP7217948.1"
                     /translation="MNDTVKEKLAESLTSDTTDILPYLPYLLQDFWELGSSPEQMLQL
                     FRKHIPFNEDTKVLDLACGKGAVSVKLAKELNIHIKGIDLIPEFIDYARRKAIEYKVD
                     ALCDFEMNDANSSVKIEHDYDCVIFGAVGDILGNYKETISKLLPTIKSKGFILIDDAY
                     VVDKSTNEQLNFERVYPTYNEWCILFKELGLKLIECIPCLELENDVEEEMNWIITRAN
                     ELIKKYPSQKDMFEQYVISQKNEYTDLQQDLVGATWILQKE"
     gene            complement(30891..31541)
                     /locus_tag="OE968_000634"
     CDS             complement(30891..31541)
                     /locus_tag="OE968_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7217949.1"
                     /translation="MNIVMINGSPKVNKNNSQYFLSELKQLIQNDNKVFTFKVDNTSK
                     YPDALNAILNCDRLIIASPLYVDGIPSHLLHFLEKCEKFLKTQNKKPIPVYAIVNCGF
                     NEGEHNHLAIQMIEHWCKKINFTWVQGIGIGAGEMFGSLESVPLGKGPKKDLGIALKE
                     LSKNILSDNIHIDDSNKSTIFISPNFPRFLYKLMGNHQWNTQAKSNGLTKSDILKK"
     gene            complement(31538..32041)
                     /locus_tag="OE968_000635"
     CDS             complement(31538..32041)
                     /locus_tag="OE968_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HCP7217950.1"
                     /translation="MRLLIHDLTDKELEKLLPKLDDNIKILPNTKEIHKCIGCFGCWI
                     KTPSECVVKDYYSNMGKLINDSDGIIIISRCCYGGFSPFVKNVLDKSINYILPYFVIK
                     DNMMRHKSRYDKQINLKAIFYGDCITEAEKETATKLVNGNAINFNIKEHSVCFYENIQ
                     DIRGESI"
     gene            complement(32090..32605)
                     /locus_tag="OE968_000636"
     CDS             complement(32090..32605)
                     /locus_tag="OE968_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HCP7217951.1"
                     /translation="MLEYIILGFLMEKELSGYDLKQIMSESTSYFFDASFGSIYPALK
                     RLETKGYIHYHEVIDGNKLKKLYSITNTGKEVFLEWLKKPINFSKTKQDHLVNIFFYK
                     YLPKEIIETNLKMLITEVELLLNKLSKQKNDAEENHCVDQYTYMYATMIYGVDYYNFV
                     INWCKDLLKNL"
     gene            32885..33409
                     /locus_tag="OE968_000637"
     CDS             32885..33409
                     /locus_tag="OE968_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HCP7217952.1"
                     /translation="MHEQIDCCERKKRTIDIKGENMRELLKWVSIINRYNTNYIDRKL
                     ADIGINNSQYFYVLHICNNPGITQDTIFEKILVNPSNITRALANLEKEGFITREPGVK
                     DKRTWHLYPTEKSLGCYDEILKITNGYVEELLSSFEKEEQELFMSMLKKVAFLAIDMN
                     EEAKLEAKENGRKI"
     gene            33393..34796
                     /locus_tag="OE968_000638"
     CDS             33393..34796
                     /locus_tag="OE968_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HCP7217953.1"
                     /translation="MEEKYKEPLEYEKVSKLLTKYAIPSIIAMLVSALYNIVDQIFIG
                     QGVGVLGNAATNVTFPLTTICTAIALLLGIGGASKCSLELGAKNSEKATKAAGNSICL
                     MAVFGISLFIVVSIFLTPLLKFFGSTSEILPYAHTYTKITSIGLPFLIMSTGMSKLIL
                     ADGRPKASMFCMLIGAVINTILNPLFIFVFNMGIAGSALATVIGQLISFGISVHYIKN
                     FQHIKLHKKSFKLDSIIYKHIFALGSSSCFNQLAMTVTQIVMNNTLAYYGARSVYGSE
                     IPLACVGIIIKVNMIFISIIIGISQGMQPIIGYNYGAEKYNRVKEAYKFAVGSATIIS
                     VIAFLCFQLFPRQITSIFGNGNETYFIFAEHYFRTFLFLTFINGVQIVSSTFFTSIGK
                     SVLGLFTSLTRQILFLIPLIVILPMFMGIDGVMFAGPIADAAAAMVCIYFAVHEMKSL
                     TIKQNNLMSNHNKIAEV"
     gene            complement(35360..35671)
                     /locus_tag="OE968_000639"
     CDS             complement(35360..35671)
                     /locus_tag="OE968_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7217954.1"
                     /translation="MKKIIKSFTFWFFLIALFEIYMHQIGQDSKSIVLIGLNPILSII
                     SRVDSFFVFMDSGMQIPCRTITGSISIYWYIASILSFLIYGIILDLIRIVISKIGNKT
                     K"
     gene            complement(35727..36320)
                     /locus_tag="OE968_000640"
     CDS             complement(35727..36320)
                     /locus_tag="OE968_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HCP7217955.1"
                     /translation="MISDSISKRRSIRKYKNQSISHETIEKIIEAGINAPSSKNRQPW
                     RFVVITEKEKESMLKAMSKGIQNEINDNGLLPGSRQHIAGANYTVEIMKQAPVTIFIL
                     NILGKSPLEKLSPEERFYEMANMQSIGAAIQNMSLTAVELGLGSLWICDVYFAYRELC
                     EWLNTDSQLVAAISLGYPDEEPSRRPRLQLSDVTEWR"
     gene            37171..37821
                     /locus_tag="OE968_000641"
     CDS             37171..37821
                     /locus_tag="OE968_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HCP7217956.1"
                     /translation="MDFISSILQGLLSILFNFTGDFGISIVLITLIVKLVLMPLSLKQ
                     RFSVKKQQELAEKMEYIKEKYKNDTKELEKQIQVSSVESMKSMLGCLIVLVQMPVVYA
                     LYHVCLDMTKEFTTIIIPWIANLGTFDNLFILPCIYTLIMLASNLVNYIPYLKINSQV
                     KFNKQMAVVTTITSLILTVRTPVAIGLYFITSAIYSLIEDICFRIYFNRKNRIVTK"
     gene            38024..38695
                     /locus_tag="OE968_000642"
     CDS             38024..38695
                     /locus_tag="OE968_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCP7217957.1"
                     /translation="MAKILVVEDEKRMQNIIVEYMQKGGYTCITADDGVEALTILKSN
                     NIDLMILDIMMPYLDGFSVCRVSREMTNIPIIILTAKGEEEDKLKGYEYGADDYITKP
                     FSPKVLLAKVNALLRRYTTDIPKNSLSLGKIFIMVASRQVYVEDKLIDLTYKEFELLR
                     LFMENPNQVFSREKLLNCIWGYDFEGNTRTVDTHIKTLRKKLGSEGHHIVTLIRSGYK
                     FEVKE"
     gene            38692..39822
                     /locus_tag="OE968_000643"
     CDS             38692..39822
                     /locus_tag="OE968_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HCP7217958.1"
                     /translation="MNSLRKIIEKLKNVDISNWIKQNFGLYSVRKKVFLLSKLSGALI
                     ILFYLVVEEFSINSKFEFWIWFIILVIFIMSIDFLLGKFISEPITSINKSAKSMSQLD
                     FSNPCTVNTNDEFGELSRSLNTMSTNLQQALSDLESANIQLEKDVNKERMLLEQRKEL
                     VDTISHEMKTPLGIIRAYTEGLIDEVDEEKKKNYMNVIIEETDRMNNMIVSLLDLSAL
                     EAGVSKLNPERFDFIEFVETVAGRLLIDIPDANFYFTYDLPEYEVFVVADKMRMEQVV
                     ENLVINAKKHVVYNGNLDLSITCENGLLLFEIYNDGRFIEQDEISKIWSKFYRSVQSQ
                     RTGGSGLGLAIVSQILTMQGLEYGVNNRDRGVEFYFMIPIDE"
     gene            40253..41098
                     /locus_tag="OE968_000644"
     CDS             40253..41098
                     /locus_tag="OE968_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCP7217959.1"
                     /translation="MIKVRELKFSYGKDKQILHGLNFEVKEGEIFGFLGPNGSGKSTT
                     QKILNGVLKGYNGHVSIFGKEVKAYTESLYQKIGVLFEFPYLYTNLSAIDNLEYFSSF
                     YPKNQRRDIYELLDLLEFKKEFINKPVSSYSKGMKQRISMARALVSNPKLLFLDEPTS
                     GLDPSGAVLFRKIIEEERKKGTTIFLTTHNMLDADLMCNNVAFIADGKIMVIDKPKNL
                     KMKNSNNKVEVEFVYNGNRDIEIVDIQELESGITFKYDEILSVHSKEPTLEEVFIKYT
                     GRMLV"
     gene            41098..42126
                     /locus_tag="OE968_000645"
     CDS             41098..42126
                     /locus_tag="OE968_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCP7217960.1"
                     /translation="MYSKFFTLVKKDFWMMIYGKFFVLTLGSLILYSCYINFGYVKFM
                     DEDSYHNNVYLYNPENISMSASPLINQVSSIGELKAKLDEDTSAVCIDMSSSKPKVIL
                     HESIKGVDNYRADYALSLLSSEKDHNSKISDNNAIIQINDKDTSEIKQRKDMTCEILF
                     FEIVAIGFLGIASLLFKEKQMGVMRITGILPVKRSLFILSKIFAFFICDLCFTVLLVV
                     FNIGFLEGIKILPQVLVQASILSIIMSLIGIGCSMLLRDFKQFSLIYLVVAVFITTPI
                     FLSANTSFEIDWIKYHPFYHVYSQLKNAFFMNFSKELVYFVVCSLTIIVLFLLVKYIF
                     NKELVREG"
     gene            42129..43142
                     /locus_tag="OE968_000646"
     CDS             42129..43142
                     /locus_tag="OE968_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCP7217961.1"
                     /translation="MIGLRYQLKSIKKDKMCIISFFLPVVMAILINFMGTIDISSLGE
                     IRFGIVKDTLPVQTEQWLKKYGMVSVYDTKMHLIREIKDIKTDTIGVVRDGKGIKTVF
                     YGNEINAIKNVGKTLPEMFRLKGDLKDVEVTILPKDSILKEFQNVFIAMILITAMFMG
                     CTFNAMNIISEKEDGISFINEVLPQSRSQYIIQKVFLGLLCGCLSSMITVFICLDISI
                     LDMIMMLLLVVFSAFISSLIGLFIGKLSEGLMVGIVYIKIVMILFIGTPLLIYLLGVN
                     TSGIGNLCYIMPSVATFNGIMEIINGNVIIIKDIVILAVHCVVWFMIYIILDKKRKLS
                     FSR"
     gene            complement(43659..44909)
                     /gene="cme"
                     /locus_tag="OE968_000647"
     CDS             complement(43659..44909)
                     /gene="cme"
                     /locus_tag="OE968_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter Cme"
                     /protein_id="HCP7217962.1"
                     /translation="MENKNTNSTWKKKVILFLASQYISLFGSSLVQMAMIWYVTLQTS
                     SGVWVTVLTVCSFIPQMIISFFAGVWADYYNRKVLIIVSDSTIAISTLVLILFMMSSN
                     GTTSELIAISVISVIRSLGSGVQTPAVNAMIPQLVPEEHLMRFNGINSSLQSIVQFIV
                     PIVAAAILGFGNKINQVLLIDVFTAIIAIVLLIFIKIPKHDIPKQTEKVSFFADMVSG
                     IKYCFSDKFIRKVLFTYGAFMLLCVPSGFLIGLLIERTFGKGYIYLSIIEMIGFLGMV
                     LGGLIIGVFGGFKNRNKTFFLAILSYAIFSIILGLVTQAWQFFIFMFFTNFSIPIIQA
                     SAMTMLQEHVAPQMLGRVLSLPIIIYTGFIPLGMMIFGPMADVISINNLIIIAGIILL
                     FFALAIPYSKQFYKQGISKSNESE"
     gene            complement(44995..45741)
                     /locus_tag="OE968_000648"
     CDS             complement(44995..45741)
                     /locus_tag="OE968_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HCP7217963.1"
                     /translation="MDTYTTSEVADLIGVHPNTVRLYEELNLIPKPKRNTNGYRIFND
                     FHIEQFRFARTALKIEVVQRGLRKDALEIVRTSANRDFDKAISLVNQYLQQLEIEKSN
                     AEEALTIVAQILNGNTPETNKLFLTRKETAEHLNVTIDTLRNWEMNGLLKVKRKQNGY
                     RVYTDEDIKRLKIISALRCANYSLSAILRMLNALSSSPNTNIKTVLDTPKDDDEIISV
                     CDKLITSLKEAEHNAKTMKSHLQIMKKQFS"
     gene            complement(45894..46916)
                     /locus_tag="OE968_000649"
     CDS             complement(45894..46916)
                     /locus_tag="OE968_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HCP7217964.1"
                     /translation="MNKNNCLDLIFEKVDPSSVGMSSEKLSQLEPLIISQYSNINGII
                     IARKGKIVFEKYYNGYNADDTFHVASVTKSIISALIGIAIDKGYIKDVDQKVVDFFPE
                     YTCSPSEICKKAVTIRHLLTMTAPYPFKNMTESLERLCKQKDWIKYTLNQLGQKGEIG
                     TFKYSSAGTHLLSAIITKTTGKSAREFANEYLFKPIGMKVIPDYDMKDFGFEDFFGKN
                     LKGWAKDRQGYSIGGWGLTLSARDMLRFGFLYLNDGIWNNKRIISKSWIEESVKMNSN
                     EYGYLWWLCKKDGVLWYSAMGTGGNAICCIPQYDLVIAIPSKIVFKPRDRWEFIEKYI
                     LTSIID"
     gene            complement(46916..49336)
                     /locus_tag="OE968_000650"
     CDS             complement(46916..49336)
                     /locus_tag="OE968_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HCP7217965.1"
                     /translation="MKEIKINGAKIHNLKNIDVSIPKDKLVVATGVSGSGKSSLMFDI
                     VFEEGRKQYLQSLGILAGIDSEDKFDNIQGLAPTIAVQQNIIRQSNPRSTVGTRTNIL
                     NMLTLLYSVEGQIMCTMCDTPVSDNLICNNCGYEEERLRPSYFSYNSSDGMCMKCSGH
                     GAYFEINIEKLVLDKHDTLKQVLDRAKITPGYLRVFSKKFNDYLDIQFLQLPEEIRNE
                     VLYGHYENGKKSSSLSKVFHNRYKRGEDLNGVYTMTACSDCNGFKIGEEARRVLLNGK
                     HIGELGKMTILEIDDFLKLLINQGNLNTFGTNLVNDILSKTQHLIESRLGHLSLYREM
                     STLSGGEMQRLFLNSHLDSEMDSLIYVLDEPTAGLHESEKIDILKSLKKLKDLGNTVI
                     VVEHDKNTIEMAEHIIDIGPKAGVEGGQLVYQGDLEGLLQSDKSLTGQYLSGKYPMPN
                     RTSNKNITHTDKIPCITIQNANTNNLKNVTVSLPLGAMVGISGKSGSGKSSLISDTLL
                     PLLRSQFNNHTINNQINSSESEIGEEDDYAVVETIADRLIGTKHISGYSEISQSPIGK
                     NMNSTPASYIGIWDKIRTLFAGQPESLEQGFTAGHFSFNSKGACPKCSGSGYEKVWLG
                     NNLSIDHICSECQGKRFNDESLSIKYKNKNIHDILNMSVSESVHFFKDIPNIVSHLNV
                     LEQIGMGYIKLGQPTPTLSGGESQRIKLAKEIGKKRNGNILYVLDEPTTGLSLYDTSK
                     LIQLLDELVENGNSVIVVEHDIDVLNVCDWIVELGPEGGDKGGYIIAEGSPKTLKENP
                     KSITGRYL"
     gene            complement(49422..50342)
                     /locus_tag="OE968_000651"
     CDS             complement(49422..50342)
                     /locus_tag="OE968_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HCP7217966.1"
                     /translation="MTNAKSKKEYLNRICKVQDYIEEHLHEPLSLDELSNIAGFSKFH
                     FHRIFKAIEKETLAQYVNRLKLENATAFLIHRTDMTVTDIAHYFGFTDSAVFSRAFKN
                     YYKISPIKYRNNYSKNCKEPYKISQYNRSISKPKCKNTREVKGEIEILELDNMNTIYT
                     RYTGSYGNLTSTFPKLLERLFTYASEQNLLGLENTQILAIYHDNPQFTQEHQLRTSIC
                     MTIPDNIVVKENDNLGNMIIPSGKYLVGHFDISKSEYSDAWDFMYNEWLSNGNYKLRA
                     SFPFEVYLNNPHNHPQNRHLVDIYLPIEPF"
     gene            50932..51858
                     /locus_tag="OE968_000652"
     CDS             50932..51858
                     /locus_tag="OE968_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conserved phage C-terminal domain-containing
                     protein"
                     /protein_id="HCP7217967.1"
                     /translation="MSNSFYQLNSAVLYFNEKRDVNRIRFNHYVMRKENIQRLKGTLP
                     RGQFMMTVRKAASDLDVSISTISRLVNEFIDLGILRLISRGVKGNCCSVYSYVCSESS
                     NAEIVTKNGDIFKNIEKYIDATINNNQKTMKYKHRNELFKNSNTNIYSRINQESIDKD
                     YDLIIHTGYETENETKKKELLKNNLNKKNLNKNTFENSDEDLTEDSTYKNPESIHEII
                     IRKLNSESGKNFKADLSITKALIDKRLKEGYSLEDFYKVIEAKVRRWRYTDMEIYIEP
                     TILFGYEFESYLNEESSLSACNYGDMCYEDMY"
     gene            complement(52241..53893)
                     /locus_tag="OE968_000653"
     CDS             complement(52241..53893)
                     /locus_tag="OE968_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp21"
                     /protein_id="HCP7217968.1"
                     /translation="MNKKNLAILISGMMFFSSSSAIFADNTTKQERLIGKTRYETAVE
                     VSKLGWVQSKTAIIVNGNSIQSALCANPFAKLKNAPILLVNNNSIENSTKAELKRLGV
                     DNVYIVDSGNSISSKVENEIKSLNIKINKIVGNNIYEMSTNVLKEIDKIKKIENVAVV
                     NGLKGLSDAVSIASPAAIHNMPIILVSDENSNDSSINFLNNRSIKKSYIVGGNKILSD
                     NTVKKYPNRERISGSDRNNTNAKIIDKFYKDKKINNVFVAKDGINQENALVDSLSIGV
                     LAAKENSPIMISNGSLVNSQKEFIKNKDIDEITQVGGGYNQKAFEDILKLKNVNIRNK
                     TKKISLIQAKEILKQALPGSNILVCYYDEDDNEYDCKVIKDNILYEIEIDAYSGKIIE
                     IEKDDDLNDNNLGTQNISLDKAKSIALDAIPNGNLIYCKYDAEDNEYEAKVIKNKKTY
                     ELEISAFDGRIVDIDMDNDSDDDFDDNDKNNSNTNDNSSIISAEKAKSIMLDKVPGGK
                     IVKFKYDEDDKEYEGEIIKGKTEYEITINAITGKILEFEIDD"
     gene            54492..55613
                     /locus_tag="OE968_000654"
     CDS             54492..55613
                     /locus_tag="OE968_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HCP7217969.1"
                     /translation="MEAKKLGFGLMRLPIKDENDVTTIDMEHLNKMVDTFLERGFTYF
                     DTAYVYHMGKSEIALRESLVKRHKRESFTIATKLPLMALKKKEEQETIFNEQLEKCGV
                     DYFDYYLLHNIGVSHYEVAKKFDSFKFIEEKKKEGKIKNIGFSFHDSAELLDKVLSEH
                     PEVDFVQLQINYLDWDNESIQSRKCYEVAEKHNKPVIVMEPVKGGTLAKIPEKAEKLL
                     NDYNPDMSISSWAIRFAASKDNVMMVLSGMSNMEQLLDNTGYMQNFKPFVQEEYNIID
                     EAVEIINESILIPCTACQYCVEGCPKNIAIPNYFALYNAEKQALNTGFSTQMVYYNNY
                     TKTYGKASDCIECKQCEESCPQHIKIIDALKNVAETFEK"
     gene            55649..56062
                     /locus_tag="OE968_000655"
     CDS             55649..56062
                     /locus_tag="OE968_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HCP7217970.1"
                     /translation="MTISEVSKKYELSADTLRYYERIGLIPPVNRNKSGIRSFTEEDC
                     EWVNFIKCMRGAGLSIETLIEYVAMFQQGSSTIKARKELLIEQRNQLAKRIEEMQKTL
                     ERLNFKIDRYEEGIIEKEKVLKSSRNKKMEAVSYE"
     gene            56055..56594
                     /locus_tag="OE968_000656"
     CDS             56055..56594
                     /locus_tag="OE968_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HCP7217971.1"
                     /translation="MSKNVLIVSASPRKGGNSDLLCDQFIQGVLESKNQVEKIFLKDK
                     DINYCTGCGACYEKEANCSQTDDMGEILEKMIGADVIVLATPVYFYTMNAQMKTMIDR
                     TCSRYTEICDKDFYFIVTAADENVADMERTIEGFRGFTSCLNGSKEKGIVYGVGAWNV
                     GDIKGSKAMKQAYEMGKLA"
     gene            complement(56794..57279)
                     /locus_tag="OE968_000657"
     CDS             complement(56794..57279)
                     /locus_tag="OE968_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7217972.1"
                     /translation="MSKSELTAETTEEMLEVLSGKDYDIACHLHELGKSLDCKIEPKT
                     GARSYKIVYSTKKPKRSLFTIECNEKKWRVKANLFHLNTYKDAVEECSKTIKDSITKT
                     RTCKKCNSKCIGGSSFELDGKSYLTCIGSGHYFANMEEMDWKNLEKLITKENNIMQES
                     V"
     gene            58184..58561
                     /locus_tag="OE968_000658"
     CDS             58184..58561
                     /locus_tag="OE968_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003483933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HCP7217973.1"
                     /translation="MSKVVIATEKAPGAIGPYSQAIQVGNIVSTSGQLPIDMKTGELV
                     SDPKEATKASLDNVKAILEQAGTSMDKIFKTTVFVKDLKDFNDINEVYATYFKENPPA
                     RSCVQVAQLPKDAVLEIEAMAVL"
BASE COUNT        21860 a         7168 c         9678 g        20047 t
ORIGIN      
        1 tagtttaatt agtatatgtg gtacaaaaag ataataattt tataattata aaagtgaaat
       61 attaaatgaa atttataact aaataaaaac ttttaaacag caatcaaaga tttgtaataa
      121 aatacatccc ttataaatat atttattata taagctgata ccagaaatat aagaattaac
      181 aattgtggag ggataaaata tgatagctgt taaagatgag aataacgtag taaacttaag
      241 aggggagtta gacaataagc tagaatttag ccatgagata tttggagaaa aattttataa
      301 tatgaaaata aaaataaaca gactaagcga ttcttttgat atacttccaa tgactgtatc
      361 agaaagactt ctccaagata ttgaccttga taaacaaaat ttagtcaatg tcgtaggcca
      421 attaagatca tataacaaaa cattaaataa taaaaataga ttagtgctta cagtgtttgt
      481 cagagaaata aaaagcatag acgaggaaaa taaagaccct aatagtatat ttttagatgg
      541 atatgtatgt aaggaacctg tgtataggaa gacaccttta ggaagggaaa taaccgattt
      601 attagttgct ataaacagac cttataataa atctgattat ataccatcaa tagtttgggg
      661 tagaaatgct aaatttgcaa agaatctaaa ggttggtgat agaatacagc tttggggtag
      721 ggttcaaagt agagaatatg agaaaaaaat agatgaaaat aatgtggtca aaaaaatggc
      781 atatgaagta tccatatcga aaataaaaaa attggatgaa aataacaatg aataaacata
      841 aaaaatagac tgatttttat gaataaaatc ctaataaatt tggtataata tcatattaaa
      901 atgtataaag attgtttaaa aaaatactaa tgaaatatct cttgaatagt tgctcgccat
      961 ttattataat gtaatctgta cataatttat aattgaggaa atgaagaggt gaagcattgt
     1021 gaaaagcata ttatgtcaga taaataaaca gccggttaaa gctaaatata catctgatga
     1081 attagaatgt tttttggata caattgagta taatgtaggt gataaaatat tgcttgttgg
     1141 tcatatagga aacctaggca agagattgag aggtcttgga acttctgtaa ctatactgga
     1201 gaatagtaat tatgaagatg tctgttattc tctagtgtat aatgaaaatt gcaatgtagt
     1261 taaaggtaag ttagagtttc taccatttga tgataatcag ttcaacaaga taataatagt
     1321 tgaccaattt aatgttatta cagattgtga aaaagcttca tctgaaatac aaagagtgtt
     1381 aaagggcaat ggagaggtta tattagagga tttaaattta aagaatttaa aagttaagtt
     1441 aaactatctt aaacataaat tttgtggttc tgttgcaaag attcactatc cacatgaagt
     1501 atttaatata ttttcaagat taaactttga tggtatgatt aaagagtcaa ataaattaaa
     1561 atatatttat gtgggaaaaa gaagataaat gagttaaaat ataaatatgg atataatata
     1621 aaagactagg ttaagcctag tcttttgtta taaggagatg tttagatgga aataaattat
     1681 gagttaataa taattgttat gctctttgta atcctgatgt caatccaatt tactttaaat
     1741 aagatatact tgattcttaa agaaataaga caaatactta tgttaaagaa aaataaggaa
     1801 tgatgattat gataggttta gaatatataa aatctgatat tcaaaatata gctgaagcta
     1861 tagtatcagt actcaatata gatgtaacta tagtaaataa ggagttattt aggattgcag
     1921 gtacaggagt atatatagac aaaataggtg agaaagtaga taaatatacg gcttttaaaa
     1981 aatcacttac agagcagatt acaatactaa ttgatgaccc aaagagtagt gatatatgta
     2041 gggaatgcta taaaagtggg gcttgtgtag agtttgcaga ggtgtgttgt cccattatat
     2101 gtgatggagt ctctcatggt gttataggcc ttatagcctt tacaaaggaa caagcacaga
     2161 ttatagaaaa taataaaagt ggtcttataa actttttagg caaaatggca gacttaatat
     2221 ctaataaatt aaaagctcaa attaaaactt atgagcttga attagaaaag aaaaaattag
     2281 agacactgtt aaacaatatg gacaaagctg ttgtgtctat tgatgtggat ggaaaaattg
     2341 ataaatataa ttcaaaattt aaagagcttt tcaatataaa ggatagtata actggcaaaa
     2401 acatatttgt cgaattagat tttataaaga aaccttctat aaataacttt aagaaagaca
     2461 aatcctgtag ttttttttat aaaagatacg gatatgattc gaagggaata tacaacatca
     2521 ataaaatagt attaaaaaat gagttaaagg gatatgttat tgattttata gataaaagag
     2581 atgctataaa aaactacaat aagatgaata aagattatag aataaaattg gaaaacataa
     2641 ttggagaaag tgtagctata agaaattcta aaaaggaagc cctaatagct tctaaatcaa
     2701 catcaacagt acttattact ggggaaagtg gaacgggtaa ggagctattt gcaagagcca
     2761 tacacaacca tagcaataga gtagataatc cttttatagc tgtaaactgt gctgctatac
     2821 cagacaattt attagaaagt gaattatttg gatatgaaga gggagctttt actggagcta
     2881 aaaaaggtgg aaagcttgga atgtttgaag tagctcataa gggaagtata tttttagatg
     2941 aaataggaga tatgagtttg catttacagt caaagttatt gagagtatta caagaaaagg
     3001 aacttaataa aattggaagt aaatcaaatg tttcaataga tgtaagaatt attgctgcta
     3061 caaataaaga tttagaaaaa atggttcaaa atggcacttt tagagaagat ttatactata
     3121 gattaaatgt tatacctata aaattaccaa gtttaagaga gagaaaagaa gatatcccac
     3181 ttataatcaa gcatatggtt aaagagtatt caaaaaaatt agataaaaat gttattgaca
     3241 tagatagcag ggttgttgat gctatgatgg aatataagtg gccagggaat ataagagagt
     3301 tgcagaatat tattgaatat agtgtgaata tgtcttcttc ttcaataatt acaatgaatg
     3361 taattcctca aaaaattaag aatacctctg tagaagagtt agaagttaaa agcgatagga
     3421 taattccact tgatgaacta gagaagattg agataataaa agctttaaat aagtacaaag
     3481 attataaaaa agataaagaa ttaacagcta aagcacttgg aatatcaaga gctacattat
     3541 atagaaaaat tgaaaaatac aatataattt catagtaata taataaaaag ctatataaaa
     3601 tttaaatttt tctaaattca taactttaaa gaaagcttta aacttatact ataagtgttt
     3661 tgcagaatct ttttttatga attaaaaaat ggtttttata agttaaaaaa taatatattt
     3721 gagccgtctc aaaatgatat agaatctcat tttgagactt ttttttgtct ttttgcgaaa
     3781 ttgtcatatg tttctccatt ttaaagaata taaatactct atacaaataa aaaaaataca
     3841 taaatagagg cagtcatacc aatggttata gaatataaga ctaaaaatat aaaaagatat
     3901 aaaaaatatg gcatgtattt tgctataaat atagataaga aattatttaa ttaattattt
     3961 gagtactaaa tctaaactta attgggaggt ttatatataa tgagagatat aagaaaagaa
     4021 ttagtggaaa tgttaaaggc agaagttaaa ccagcagtag ggtgtactga accagtagcc
     4081 ttagctctag catgtgcaaa ggcaaaggaa ttattaggag aagaaatagt tgaaaatcgt
     4141 atgttagtta gtcctagtat ttataaaaat ggtatgtgcg taggtatacc aggtactgaa
     4201 agattaggat taaaaattgc agcagctcta ggtatagtag gtggacattc tgaaaatgga
     4261 ttaagtgtgt tagaaactct aacaaaagag gaagttaaaa tagctgagga ttatatggat
     4321 aatactccac tatcaataac acctgctgat acaagagaga aagtatttat agaagttgtg
     4381 ttaaaaggaa aaaatcatat tgctaaagtg agaataagaa ctaaacatga taattttacg
     4441 ttcttagaaa aagatggaga agtattatta gacaatgaac caaaagtatc agcttcaaat
     4501 gatgcggcag aaaaagctga aagtttaatg gatacagtaa ctatacaaga attaataaaa
     4561 aatgtagaag gaattgattt taaagatata gaatttttac tagatggagt aaaaatgaat
     4621 gaagagatgg ctgaatatgg attaaaacaa aaaactggta ttggtgtagg atatggaatt
     4681 aaaaagtcta tagaagaagg tcttttaggt aatgatgtta taaattatgc aatgatgtta
     4741 actgctggag cttcagatgc aagaatggca ggggtaaaaa tgcctgttat gagttcaaat
     4801 ggaagtggaa atcatggatt aacagcaatt cttccaatcg ttgcttataa taaaaaattc
     4861 ccacaatctg atgaaagact agcaaaagct ttagctatat ctcatctagt aactggttat
     4921 attaagaact atacaggaag attatctgct gtatgtggat gtggtgttgc tgcttctact
     4981 ggagcaactg ctggtatctc ttggcttatg aatggtactg aaaagcaaat agaaggagct
     5041 atagaaaata tgatagctga cttaagtgga atgatatgtg acggtgcgaa agctggttgt
     5101 gcattaaaat tatcttctgc agcatctgca gctatacaaa gtgctataat agctaagcaa
     5161 gattgttttg taccaccact aaatggtata gttggttcaa gtgttgagca aagtatacaa
     5221 aacttaggta gagtaagtga caaaggtatg tctataacag atgagataat cttaaatgta
     5281 atgaatgata tgaataaagt tgactagtac tttataatat gttttgtatt atgaggtata
     5341 acaaaaatag cataaataaa tttaattagt accctctaat aaaatatgat tatgtataaa
     5401 tttatgtata atagaaaaaa cttgttaatg caagtttttt ctttttttgt ctaaaatata
     5461 tagtatgtaa tttagtgtgg atatatgaac tacttaaaat ataagataca ttgttaataa
     5521 ttgttgaatg aacataaaaa ctcaataata ttgactaata ttgaataaga gtattgaaaa
     5581 agtgagcaat ctcttataaa attaagaagg attattacaa ttggaggtct ttttatggat
     5641 atagaaacaa aaaaatggga agtattgtat tcagaagaaa aaattaaaga taaattaagg
     5701 gaattaggag caattataga aaaagattat aaagataaaa atcttatggt agtttctcta
     5761 ttaaaaggta gctttatatt ttgtgcagac ttagttagaa atataaactt accacttaga
     5821 gttaatttta tgactacatc tagttatgga aacaatgaag aaagtactgg aaaggttaaa
     5881 gtagtttcag atgtgactac tgatatagca ggatatgatg ttttggttgt agacgatatt
     5941 actgattctg cacttactat ggattttgtg ttaaaacatc taaaagctaa aaatcctgct
     6001 agtttaaaat gctgtgttct tttggataaa ccaagcagaa gaaaagtcga tttagtgcca
     6061 gattattgtg gatttgaaat agaagataag tttgtggttg gatatgggtt tgattttggt
     6121 gattattata gaaatgttcc ttatatattc aatgttactg atgaagatag ataagcaatt
     6181 atataatttt gtggatgcct taatatgatt tttattaatc gtgttgaggt ttttttattt
     6241 aaaaagtaat taaagtagta ttaaattaat tttatgcaat ttaattatct attttttata
     6301 gcataataaa aaaattttaa ataattgatg ggaaatgagt tttttaattg tattaataat
     6361 tgtaaaagag tactaataat tgtaaaagat tttacaaaaa agtaatgaaa tttaagaatc
     6421 aaagcatata tgttgatata agcaaataga tacattatca cataagaaat tgtcgattca
     6481 tataattata tagagtaata ctcaatattt atagagtatt actctaactt taaaaaagga
     6541 ggattaatta tatgagtgat atttcaggtc caagtttata tcaagatgta ggtccaacag
     6601 ggccaacagg tgctactggt ccaacaggac cgacggggcc tagaggtgta actggagcga
     6661 ccggagcaaa tggaataaca ggaccaacag gaaatacagg agcaactgga gcgaatggaa
     6721 taacgggtcc aacaggaaat atgggagcga ctggaccaaa tggaacaaca ggttctacag
     6781 gaccaacagg aaatacagga gcgactggag cgaatggaat aacaggtccg acagggaata
     6841 caggagcaac cggagcaaat ggaataacag gaccaacagg aaacaaagga gcaaccggag
     6901 caaatggaat aacaggttct acaggaccaa caggaaatac aggagcgact ggagcaaatg
     6961 gaataacagg tccaacaggg aatacaggag caacaggagc aacaggacca accggactaa
     7021 ctggagcaac aggagcaacc ggagcaaatg gaataacagg accaacagga aatacaggag
     7081 caaccggagc aaatggagta acaggtgcta caggcccaac aggaaataca ggagcaacag
     7141 gtccaacagg aagtatagga gcgactggag caacaggaac aactggggca acaggcccaa
     7201 taggagcaac aggagcaaca ggagcagatg gagaggtagg tccaacagga gcagtaggag
     7261 caacaggtcc agatggtttg gtaggtccaa caggcccaac aggcccaacc ggagcaaccg
     7321 gagcaaatgg tttggtaggc ccaacaggcc caaccggagc aaccggagca aatggtttgg
     7381 taggtccaac aggagcgaca ggagcaacag gagtagctgg ggcaataggt ccaacgggag
     7441 cagtaggagc aacaggccca acgggagcag atggagcagt aggtccaaca ggagcgacag
     7501 gagcaacagg ggcaaatgga gcaacaggcc caacgggagc agtaggagca acgggagcga
     7561 atggagtagc aggtccaata ggtccaacag gtccaacggg agaaaatgga gtagcaggag
     7621 caacaggagc gacaggagca acaggggcaa atggagcaac aggcccaaca ggagcagtag
     7681 gagcaacggg agcaaatgga gtagcaggag cgataggacc aacaggccca accggagcaa
     7741 atggagcgac aggagcaaca ggggcgacag gagcaaccgg agcaaatgga gcaacaggtc
     7801 caaccggagc gacaggagca acaggagtgt tagcagcaaa caatgcacaa tttacagtgt
     7861 cctcttcaag tttagtgaat aatacattag tgacatttaa ttcatcattt ataaatggaa
     7921 ctaatataac ttttccaaca agtagtacta taaatcttgc agttggaggg atatacaatg
     7981 tatctttcgg tatacgtgcc acactttcac ttgcaggatt tatgtcaatt actactaact
     8041 ttaatggagt aactcaaaat aactttattg caaaagcagt aaatacactt acttcatcag
     8101 atgtaagtgt aagtttaagc tttttagttg atgctagagc agcagctgtt actttaagtt
     8161 ttacatttgg ttcaggcacg acaggtactt ctgcagctgg atatgtatca gtttatagaa
     8221 tacaatagtt tatatgatga aaagattata aaataataaa caatatgatt tcatatacca
     8281 ataaatagaa taatatttaa taggtttata tgatgaaaag actataaaat aataaacaat
     8341 atgatttcat ataccaataa ataggataat atttaatagg tttatatgat gaaaagacta
     8401 taaaataata aacaatatga tttcatatac caataaataa gataatattt aagaaaaatg
     8461 attatattta aaaggtaagc ataaaattta taaactttta gaatagaaat ctcaatcaat
     8521 tagatattca aattgatgaa tatgaatacc taaatagatt gagatttatt atgtacaaaa
     8581 cttatcctaa tatatctgac attttataaa gcccagattg cttaccaatt aaaaatttag
     8641 ctgcaactat agagccgttt gcaaatactt catcagattg agaatgatgg cttaatgtaa
     8701 gaacttcatt atcacctgca aatacaacat catggtcgct gattatattg ccacctctta
     8761 tagagtgtat tccaatttca tttggttttc ttttacaatc tctaccatat ctaccatgtg
     8821 tattttcact ttcaggcaag acttctctaa ttgcattagc tatcatagta gcagttccac
     8881 taggggcgtc ttcttttcta ttgtgatgtt tttctatgat ttcaatatca aaaccttcta
     8941 acatctttga agcatcctta actaatttta ttaatatatt tactccaaga gatgtatttg
     9001 atgataataa tataggaatg ttttttgatg cttcttctat tttatttaag tcattttcgt
     9061 catatccagt agtagctaat actacaggtg tattattttt tagagcatat gacaatattg
     9121 gctctaaagt atcatgatgt gaaaagtcta taattacatc agttttttca gttacatcag
     9181 tcattgtttt gtaaagcttt gtatcactat gatgaccttt ttcatcagca gacctagcta
     9241 caccacaaac caactctaat tcattatctt tttttacaca ttctgctaaa actcttccca
     9301 ttgttccatt atagccacta attataactt tcaacataaa ttcctcctat gaaattaata
     9361 aaaatttgtt atatttctat aagtttattt tatcactaat ataatttata taaaataata
     9421 ttagtgataa taagcttaca atttatctta cattaaaaaa tttaagtgga tttttcaaaa
     9481 tatagataaa tttctttttc attgtttaaa tgataaaaat atatttgact tcataccaaa
     9541 aagagtgccc catgaactaa aaagttaatt ttgaaatacc atattcatat atcatatgat
     9601 ttatttggaa attaatatta atacattaaa ataactaaat acatgtatgc ataaagatgt
     9661 ataaaaaata tataaacata tagtattaat tttaaattca acaatttaat tgttaaaagt
     9721 gttattatta aattagaaat atcttaactt aatatactga gatgggagtg atagatatgt
     9781 taaaagaaga aaaaacttat caagagaaag acgcaaaagt attcaatgga gtggcagctt
     9841 tgataatgat tttattattt ttagtagttt caataggtat catggttttt gggatagtaa
     9901 aacttgatag tggatttact ggaataggtt cacttatgtt aattttggga cttgtattta
     9961 tagtagtaga ttttatccta ttttttgggc taaaaatgat taatcctaaa gaagctatag
    10021 ttctagtttt gtttggtaac tattatggaa ctataaaaaa agaagggtac tattgggtga
    10081 atccattttg ttcagcaata aacccagcag tatcaagaat taatgtatcg aaatcttcat
    10141 ctgatgaaaa ggtagatata tcaactaatt caaggggcaa aaaagtatct ttaaaaacaa
    10201 tgactcttaa taatgaaaag cagaaagtca atgatttatt gggaaatcca attataatag
    10261 gagtggttgt aatttggaag gttatagatg caacaaaggc agtatttaat gtggataatt
    10321 ataatacatt cttatctatt cagtgtgatt ctactattcg caatgtttca agactttatc
    10381 catatgatgt atctgaagat ggagatgaaa aatctcttcg tggtagtagt caggaaatag
    10441 cagatagatt aaaagatgaa ttacaatcaa gggttgacat tgcaggaatt gaagtgtgtg
    10501 aagtgagaat tactcatctt tcttatgcac cagagattgc agcagcaatg ttacaacgtc
    10561 aacaagcaga ggctataata gcagcacgta aaaagattgt tgagggggct gtaagtatgg
    10621 tagagatggc attgactaat ttaagtgaaa ataatgttgt gactttggac gaagaacgta
    10681 aagcagctat ggtaagtaat ctgttagttg tgctttgtgg caataaagat gcacaaccag
    10741 tggtaaacag cagttctatt tattaaatta taaaaagttt aatagtttat tttattgata
    10801 tatagaaaat ttagtagttc attttattaa attatataaa gattaatggt ttgctttatt
    10861 gaattataaa aagtttaata atttattcta ttgatatata gaaaatttag tagttcattt
    10921 tattaaatta tataaagatt aatggttttc actttattaa attataaaaa gtttaatagt
    10981 ttattacatt gatatattga aaaattgaag gaaataaaaa tacttgtcag caagaaataa
    11041 aaatgatata agaatgaata agagaattgt aaaaaaataa aatgattata aataaaagat
    11101 aaaaatattg taaaaaagag ggtgcctctg gtgaattaaa ttcacacaga gacacctttt
    11161 taattaattt tttaaattag tatattattg tttaattaat agcatagtac tatttaatta
    11221 atctaaattt ctaaggtctt ccataagctt agttttgtca gccgtttttt catctttcat
    11281 ttttataact ttagcaggag aaccagcaac aacggcacca gcttctacat cagtagttac
    11341 aacagcacca gctgcaacaa cagcaccttt accgattcta acaccttcaa gaataactgc
    11401 attagctcct attaaaacat catcttcaac tataacagga gtagcagaag gtggctctaa
    11461 aacaccagca acaacagcac cagcacctaa gtgaacattt ttaccaagag ttcctctagc
    11521 tccaataaca gcattcatat ctaccataga accttcacca ataacagctc ctatatttat
    11581 aacagctccc atcattacaa cagcattttt ttctatagta accatgtctc ttattattgc
    11641 acctggctca attcttgcat gttcacttaa agtatttttt agaggaatag cagaatttct
    11701 tctatcatat tctacatgag tatctgttat atcatttcca tgtttatcta atacttccat
    11761 tatatcctca tagtcaccta caaatatata agaaccatta cttccaaata ccttaaattt
    11821 atcagttgat tggaagtgta aagagttagt atttacatat accttaacag gtgttttctt
    11881 tttaacttct tttatatacc ttgctatttc ataagcatcg tttaaattta ccatttgtta
    11941 attctccttg tatttcatta tatttctttt attatatact tatttgtcaa ttttagtata
    12001 tacttacttc ttattattta tattttattt tagttagctt ttattgtata gacatagtat
    12061 taaataaatt tattatatat gtttgatttg tattgcatat tattatatat atattgtata
    12121 tgtttaattt atattgtgta ttattatatt tatactatta tcccaacatg ctgtccatat
    12181 tataaaatcc tggtttttgc ttaactaagt atttggcagc agctatagaa ccacttgcaa
    12241 agataccacg agattgagct tgatggctta ttgtaagaac ctcattgtct ccagcaaata
    12301 gagcatcatg ttcgccaaca atatttccac ctcttatagc atgaatacca acttcatttg
    12361 gttgtctttt tgcactacga ccatatctac cataattatt ttcaacgttt ggcaaaacct
    12421 cttttatagc gttagcaatc ataacagctg tgccacttgg ggcatctact tttctgttgt
    12481 gatgtttttc tattatttct atatcaaatc cttctagtaa tttagctgca tctttaacca
    12541 attttactaa tacatttaca ccaagagaca tattatatga ttggaataca ggaataactt
    12601 tagccgcttc acgtattttg ttcatttcgt catcattata tccagtagta gcaattacta
    12661 aaggtgtttt agtctttaaa acgtaagata agatattatc taaattagag tgatgagaaa
    12721 aatctataac tacatcagct tcctcaacta tagtactcat atcttcataa attttaaggt
    12781 cgccttcata gctatccaga cctctagctg caacacaaac caattctaat tcattatctt
    12841 ctcttatagt atcggctaaa atcttaccca tttttccatc ataaccagtt gctataactt
    12901 ttaacataat ttcctcctat gattaagggc taacttttga ccaaacttac tttttaccat
    12961 gcattaatct ttactatgca ttaactttta gtccaaagtt aactaattct ttctttaata
    13021 cttctaaatt tgctgggtcc atttctgcta gaggtaatct taaatctcca acattgaatc
    13081 ccaataaatt cattgcagtc ttaactggta taggatttac ttctataaat aaagctgcga
    13141 ttagagcatc cataccaagt tgtaattttc tagaaccttc aatatcgcct tcaaagaatt
    13201 tagctaccaa atcgtgagtt tcttgagggc aaacattagc aagtactgat ataactcctt
    13261 gacctcctaa agataataaa ggaagtatag tatcatcatt accagagtag atagcaaagt
    13321 catctggaac taaactagct atttctgcaa cctgtcctag gtctccacta gcttctttta
    13381 cagcaactat gttatcaatt ttagcaagtt caactataag gctaggactt atatttacac
    13441 aagttcttcc agggacattg taaagtataa ttggaagttt aacactgtta gctattgttt
    13501 caaaatgacg cttaagtcca gctttattag ctttattgta ataaggtgtt attattaata
    13561 gagcatctac tcctaatttt tcagcttctt gacttaagtt aactgagtgc atagtatcat
    13621 tagaaccact tccagctata acaggaactc ttttattaac tttttcaaca acatacttaa
    13681 tagtagcaag ttgttcttca tcagtcatag tattagcttc accagtagta ccacaagata
    13741 ctatagcatc agtaccatta gctatttggt attcaactaa ttcacctaat ttgtcaaaat
    13801 caactttgtt atcctttgta aatggtgtaa ctagagcaac agcagaacct ttaaatatca
    13861 tataaaatca atcccctctt ttttattttt gtgttttata ttacagttac ttctaatgct
    13921 tgtttttgag ttactattaa tattttacaa aattatatat ttatacaagt ttgtatatta
    13981 tactaaatcg tatgataaag ccatttcagc tatttgaatt gcgttagttg cagcaccttt
    14041 tcttatatta tcagcaacaa cccaaagatt tacaccatta tcaacactaa aatctcttct
    14101 tattcttcca acaaatactt catctctatc atcaaattct acagcagttg gatattcgtt
    14161 tttagcagga ttatcaacta ctacaacacc tggagcttct tcaagtgttt ttactaaatc
    14221 atctaactca aatggattgt taaactcaac atttatagat tcactatgac cattttttac
    14281 tggaactctt acagtagttg cagttatttt taaatcgtag ttatcaagta ttttcatagt
    14341 ttcatttacc attttcattt cttctttagt gtatccattt tcagtgaatg aatctatatg
    14401 aggaagacag ttgtaagaga tttgatgagg gtagaatcca gtaggattac cgttcattcc
    14461 tttctctaaa tcttcaacac ctttaacacc agaaccagat acagcttggt aagtagagta
    14521 aacaactctc ttaattttgt atttatcatc aagagcttta aggggaacca tagcttgtat
    14581 agtagagcag ttaggattag ctattatacc cttatgattt tttatggctt ctggattaac
    14641 ctcaggaact actaaaggca catctggatt cattctccat tgactagagt tatctactac
    14701 taagattcca tttgaagcag ctattggagc atacttttca ctaatacttc caccagcaga
    14761 gaataatgct atttgtatgc ctctatcagt aaatgaagtt tcctttaatt cttctactat
    14821 atattcttta ccacaaaaca ttactttaga accagctgat ttagaagaag agaataaaaa
    14881 tagattttct attggaaaat ttctttcttc taatactttt aaaaatgttc tacctaccat
    14941 tccagtagca ccaattattg ctacatttac ttttttcata taaattcacc ccaattttaa
    15001 attattaaaa cattatttta ttttagttat acaagtaaga tatgttaata tttttatata
    15061 tccaaaaact ttaatattat attaacaact ttaattatat acaaaaaacg tacaaaggta
    15121 tactttgtac gtctaattta tcactcaaag taaaccctgt agctcatcac ctacaaaaat
    15181 aagtgacagt attacacatg ttatgtgcaa tcccagaaaa tattattgca agaaatattt
    15241 tcttcggctg taaatccttt ttccaatcat taacacctgc cagctactat tggatactct
    15301 tagttacagc tacctctacc ctaggttaat aggatattaa aatttgatta ttctaataat
    15361 aatacatatt taagaaaaaa tcaacttatt tatataaata ttgctaaaat ttaaatccaa
    15421 aatttgtcaa ttcttgtttt aacacattaa gattagtttc ttccatttca gctagaggaa
    15481 gtcttaaatc accaacatta aaacctaaaa tgttcatggc agttttaaca ggaactggat
    15541 ttacttctat aaataaagca gcaattaaag catccatatc aagttgtaat ttttttgagc
    15601 cttcaatatc accttcaaag aatttagtta ctaaatcatg tgtttcttta ggacatatgt
    15661 tagcaagtac agagataata ccacttccac ctaatgataa tagtggtagt atagtatcat
    15721 cattaccgga gtatatagca aagtctttag gtactaattt agctatttct gcaacttgag
    15781 ctaagtctcc acttgcttcc ttcacagcaa ctatattatc tattttagca agttcagcca
    15841 caacagatgg ctttatattc actttagttc ttcctggtac gttgtataaa ataattggca
    15901 acttaacgct atttgctatt gtttcaaagt gaagtttaag acctttctca ttagtcttat
    15961 tatagtaagg agttattatt aaaagaccat ccacccctaa tttttcagct tcttgactca
    16021 tatgaacaga caacatagta ttgtttgaac cagtacctgc tataacaggt attctcttat
    16081 taactttttc aactgtatat tttattacag caaaaatttc agattcactc atagtagtcg
    16141 cctcacctgt tgttccacaa acaactagtg catctgtgcc attctcaatg tgatattcga
    16201 ttaattcacc taatttttca aagttgacat tattatcctc tgtaaatggg gtaactaaag
    16261 caacagcaga acctttaaat aacatataat caaatctcct tttttatcta aatttaattt
    16321 tttaagtaca ataataatta tagtacaaat taattaattt taataggtat agttaatatc
    16381 ttaactgttt aaataagata tttatattat attaatatta gaaaaatttt aaataaatgt
    16441 tttattctca aaatatgcat attaatttaa taaaatatac caaaatggaa ataaaaaata
    16501 aattttatga gaatttaata actaataatt aatatattta ggttataata aatatgtgcg
    16561 taaaatctaa caataagcaa taataccgta aatttaggag gaataatatg gatactttaa
    16621 aggaactttt taaaatagga agtggacctt caagttctca tactatggga ccacaaagag
    16681 cagcagagag atttaagaat gaaaacccag atgcagaaag ttttagagca atattatatg
    16741 gtagtttggc agctacaggg aaaggtcact taactgacta tataattgaa aaaactatag
    16801 cacctaaaaa agtcgaaatt gtttgggaag aagatattat aaaagatttt cacccaaatg
    16861 ggatgaagtt tgaagcttta gataaagata aaaatgtaac agctgaatgg actgtatatt
    16921 ctgtaggtgg aggaactata gcagaagaag gtcaaagaaa cagtaaaagc aatagtatat
    16981 atcacttaga tactatggat gagatagtaa aatggtgcaa agaaaataat aagactttgg
    17041 tagattttgt gttggaatgt gaaccaaaag acataaaaga ttatataaaa actataaaag
    17101 atgctatgag aaaatctatt gatgatggac taagtacaga tgaaataata ccaggcaagt
    17161 tattattaaa aagaagagca agtacatttt ataatgcata taaaaaagat aagagcttct
    17221 caacacttgt atatgcatat gcactagcag cttcagagca aaacgcttct ggtaatataa
    17281 tagttacagc accaacttgt ggttctgctg gagtaatacc aggaatattc tttgcaatgc
    17341 aggatttcta taattatgat gacgaaaaaa taattgaagc actacttgta gctggaataa
    17401 taggtaatat aataaaaact aacgcttcaa tatctggagc agaggtaggg tgtcaaggtg
    17461 aagttggagc cgcttgttct atggcagcag cagcagtagc atacttaaaa ggtggaacta
    17521 tagaccatat tgaatatgcg gcagaaatag cacttgaaca tcatttagga atgacttgtg
    17581 accctgtata tggatatgtt caaattccat gtatagaaag aaatgcaatg gcagctcaaa
    17641 gagcttatga tgcagctaat tatgcattat taactgatgg ctcacattct gtctccttag
    17701 accaagttgt tgaaacaatg aaagaaactg gtatagatat gatggataag tacaaagaaa
    17761 cagctaaggg tggacttgct aaacatttct tctcttgcta aaaataaaat tttccaataa
    17821 taattcctct gttttgattt atgaaacagg ggaattatta ttaatggtga attatttaat
    17881 aatgcaaaat atttttatat tcaatttagc tttttatttt taattagtat aacatgctat
    17941 ataatatttt aattataaag aaatatagaa atatttttta ataaattaga aattggagga
    18001 gattacatga gagaggcatc atatttacaa gaacaacttt ataaacatag gaagtcatta
    18061 aatcctattg cagagattgg gagaaaagag tataagactt caaaatatat aagagattat
    18121 cttgataaat taggaattga gtatgaagtt tatttagaaa caggtatagt aggtgtaata
    18181 gaaggtaaaa gacctaaaaa agatattgct tttagagctg acatagatgg tcttcatagt
    18241 gaagaagggg taaaacattt atgtggtcat gatggacatg ctactatctt acttggatta
    18301 attgagtatt taaatgataa taaagaagac ttaaatgata atatagtatt tatattccaa
    18361 ccggcagaag aaggtcctgg gggagcaaaa gctttaatag atgaaggagt gcttagaaaa
    18421 tacaatattg atgaaatata tgggcttcat atatatccag agttaccaga aggttatgta
    18481 ggtacaagag agggctattt tatggctcaa ataggagata ttgacataga aatagtgtct
    18541 aaaagtggac atggggctat gccacaaaat ggtattgatg gtatagtgat agcttcaaac
    18601 tttgtaagct cacttcaaac tatagtgtct agaaatataa gcccaataga caatgcagtg
    18661 ttgactattg gcagaattga agggggagct agaagaaata taatagctga aaatataaag
    18721 atggaaggta ctatgagatg tttcagccca gaagtgtatg agaaaatgaa gcttagagtt
    18781 agagaacttg ctagagggtt tgaattggct tataactgta aggttaatat aaatattata
    18841 gatgattata tcgctgttaa aaatgacaag gatttgtatc aagagtttgt agaggctatt
    18901 ggaagtgata ctgttgtaga gttagagcca cttatgatat cagaagattt ttcttattat
    18961 caaaaagaag ttccaggatt attttttatg ttgggttcaa gaaacgaaga aaaaggattt
    19021 gtaaatggtc ttcataatat aaactttaat tttgatgaaa agatatgtgt aaatgcattg
    19081 aatgtttatt caaaattatt aaaatacaaa gaagcaatag attaggaaga taagttataa
    19141 agattaaaaa gcataaatac ctaaatttaa aaaaagtgta ttaataaata ccccttacat
    19201 atttgtataa atttatttta attgacaaaa atacaaataa gaaggggtga tttttttgaa
    19261 agaaaaagta caaagagaaa agaagataac taatggcaag aatactaaaa tattgacaaa
    19321 tgatgatata atgaaatatg agatagcctc agaactaggt cttatggata aagttggtga
    19381 acgtggatgg gcaggactta cagctaagga agcaggaaga attggaggta tgcttacatc
    19441 acgcaaaaag aggcttaaaa agattgtgga ggagcagaat aaaaaggatg agtcaatata
    19501 gtgattttgc gtttgtatat gatgaactta tgaatgaagt tgattataat ggttgggtta
    19561 aatatataga agatataata gatagtgaag gtgtaaaagt aaaaaatata ttggaattgg
    19621 catgtggcac gggtaatctt acaattccat tgactaaaaa aaattacgat atagctggta
    19681 tagatatatc tgatgagatg cttagtgtag caagagaaaa gtcagaaaaa gaaggagtag
    19741 aattagtttt acttcaacaa gatatatcag agcttgattt tgaaatatct gatttggact
    19801 gtgtactttg tgcttgtgat ggattcaatt atataactta tgatgatgat ttggaaaatg
    19861 tattttcaaa gacatatgaa ttattaaaga aagatggaat attcatattt gatataagtt
    19921 ctttttataa attagccaac atattgggaa ataacatgta tggagaaaat agagaagata
    19981 tagcgtatat gtggcaaaat tactttgatg aagaagagaa tctaattgaa atggaactta
    20041 cattctttat taaagatgaa tgtggaaaat ttgaaagatt tgaagagata caccaacaaa
    20101 gagcatatac tgaagatgag atagttgata tgcttgaaaa atctggattt aaggatataa
    20161 aatattatgg ggattttaca tttgacaaac ctagtgaaga aagtcaaaga atcttctttg
    20221 tatgtaaaaa ataagatatt tttgactata taagataatt attaaaaata accatgatat
    20281 aaaaatatag aaaatgcagt tttatagatt aaaagtaaag tgatgatact ttatgacttt
    20341 tattttttaa taattataaa gttctataga taaaaattaa aatataataa ctattgctta
    20401 gtaaaattaa aataaaatgg gttttgccca aggttaagat agataagtat ttatagatta
    20461 aaattaaggt agtaatataa taaaaataag acaattaacg ggacatggag gaatattaat
    20521 gagagattat gtactaagag cgacatcagg aaatggtcaa gttagagcat ttgtcgcaac
    20581 tactagaaat acagtagaag aagctagaag attacatgaa actacaaaag tagcaacagc
    20641 agcacttgga agaacattaa cagccacatc tataatggga ttaatgatga aaaatgatag
    20701 tgataaattg actgtaataa taaaaggtgg aggtccaatt ggaactatta tcgccacatc
    20761 agactctaag ggaatggtaa aaggatatgt aggaaatcca caagtagagg ttgaagacta
    20821 tccaaatgga aagttaaatg tagcagcagc agtaggtaca gaaggtgttg taaaagttat
    20881 aaaagactta ggtcttagag aaccatataa tgggacttat ccattggtaa gtggagaaat
    20941 tgcagaagac tttacttatt attttgctgt atcagagcag actccatcag tagtagcttt
    21001 aggtgttctt acaaaagaag atgaagtaga gtttgctgga ggatttatag ttcaattaat
    21061 gccagatgca gaagaagaga ctattgctaa gttagaggaa aatgtagcta aattaccttc
    21121 tataactaac atgttaaaag aaggaaaatc accagaggat atattaaata ttgttttgga
    21181 tggtttggaa cctaaaatac ttgatacctg tgaagttggg tttatgtgtg aatgttcaaa
    21241 agaaagagta aaaactgctt tggttgcaat tggtaaaaaa tcattggctc aaataataga
    21301 agaagataaa aaagcagaag ttggttgcca gttctgtaat aagaaatata tgtatagtga
    21361 agaagagttg cttgaaattt taaaggaaat gtagactata aaaatagttg tattgatata
    21421 agtaatgtta tagtgatata gtaaagtcgt attgatatag taattaaagt ataatttatt
    21481 aataatagac atatttatat taaaaaataa gtttaataaa tttttaagct taataaattt
    21541 taagaattaa gaagctttct ggctgtaatg tttgcaatgt tgcagttaga aggctttttt
    21601 attttattat agttcgtgtc aaagattgta tgaaacaata aaatattgta aaataatttg
    21661 tatatttaga cctgattggc acaaaggttt ataaggtatt tgagttgatt atgcgaaatt
    21721 ctatgaagta gtaaccctgt gactttaatc atgggaggtt cagaagaagg agaaaatttt
    21781 aaatatggaa agtaaaacga agtacatagg aataagtata ttaatattat tgatgatatt
    21841 tttaattgca aaaaatttta acggaaaact tgaaatacct attcctgaga gtaatagtag
    21901 aaaatttaaa tcagcagcag tgttttatcc tcaacatcaa gatgatgagg ttttatgggg
    21961 aggaagtgcc attgtagatg ctataaaaca gtgtggtgtt gataatgtat atgtggtatt
    22021 agtatcagat ggttctggag ttaacgtttt caaagctaac acaaaattta gaaatttaac
    22081 taggaagcaa aaggaagaac ttagaaataa cgagtttaaa tcagctttga gagagcttgg
    22141 agtgaaacct caaaatgtga ttatacttgc agatatagat aaaaaggaag gcacacatta
    22201 tgaattaatg gaaaagacta tattggattt tgaacataag tttaaaggca atgtgaccca
    22261 tatagcccat cactataagt atgatgacca tataatgcat agaaagaatg gggaagtttt
    22321 aaagaaactt aaacgtgaag gtaagataaa agatgacttg tattttgtta agccaaaata
    22381 tgtaaagtat ataccaagaa atgaaagagc tatctataaa gcaatggatt ttgatgacta
    22441 caataaggtt aagagtgctt gttatgaata taaggttgta aattcaaagc gtaaaatgta
    22501 tggtatagga tatatttcgg cacatagtta ttttgaacat cttctaaatg accctgaact
    22561 tacgtctgta ttaagtgaag attaatttct tataagtagt aagttatgtt tgataagttg
    22621 attggaattt tctatagttt tgaaggtatt ggaaatttag ttttatttaa agatttaaag
    22681 atagaggttt ttagtgttta aaattttaaa gttaagttga ataattgtat agaattattt
    22741 gtgaaagaag aaacagtgta aaacatagta tcttatttat ggttttaaaa tcataggcaa
    22801 gatacttttt ttatgtaact aataccattt tgagattatt aacttaagaa ttttatataa
    22861 tttaacactc atatataatg atgatattta ggtagaatag atgcaattac gcttaaataa
    22921 aataactgta ttttttataa aaatcaaacc ctacactata ctaccagata aaatctacat
    22981 gctataattt gacctgtgtt tataaaaaaa ggagtaatct aataaaatag tatttcactt
    23041 atgtataact aacaactatt attacgattt tctctaaata atttaaagaa aaataatgca
    23101 ggaggtaaaa tatgaacaat gaatttataa ttttaaaagg ttgcaaagag aacaatttga
    23161 acaatatttc cttaaaaata ccaaaaagaa aaataaccat attcacaggg gtgtcgggtt
    23221 ctggaaagtc atctattgta tttgagacaa ttgcaaaaga atcacaacgc caactaaatg
    23281 aaaggtttag tacatttgta agaagttttt tacctaagta tggagaggtt aaagctgatt
    23341 gtatagaaaa tttgtcaaca ccaattatca tagaccaaag tagacttggt ggaaattcaa
    23401 ggtcaaccct aggtactatt acagatgtaa attccttttt aagagcttta tattcaaggt
    23461 ttggtagtga gtatataggt aatgctaata tgttttcttt taataatatt gatggtatgt
    23521 gcccacactg tcatgggctt ggaaaaaagc tagttcctaa tatgaaccaa attcttgata
    23581 tgaataaatc attaaatgaa ggtgctatat tgctttcagg gtttggagtg ggttcttggc
    23641 attggaatat attcgctgaa tcaggatttt ttgatattaa taagaggata tgtgattatt
    23701 cagaagtaga attggaaaag tttttgcatg gtaaagcaga aaagattaag atagaaaatg
    23761 ctggtcaaac taacatgaca tatgagggat taatggttaa atttaatcgc ctatacttaa
    23821 gtagagaggg agaaatatct gaagctacta agaaaaaatt gagtaaactt cttatagaag
    23881 atagatgtcc tatatgtgat ggaagaagac ttaatgaaag agtatatagg tctttaatta
    23941 atggttataa tatagcagat ttaactagta tgcaaattga tgaattggct gaagttatta
    24001 aaagtataga tgagccagaa gcacaacctt taattaaagg aataatagaa aagttaaaca
    24061 gtatcataga tataggtctt ggatatttaa cactggatag agagacatct tctctatcag
    24121 gaggggaatc tcagcgtata aagatggtta agtatttaaa tagtaatctt gttgatttaa
    24181 tgtatatttt tgatgaacca agtgtaggac ttcatccaaa agatgtgtat aaattaaata
    24241 atcttttaaa aaaattgcgt gataaaggga atacaattat agttgttgaa catgacccag
    24301 atgttattaa gattgcagac catattgtag atgtaggacc aaaggcaggt aagtatggtg
    24361 gagaagttgt gtatgaaggc agttatgaaa atctacttac aagtggtact ttgacaggga
    24421 atgctttaag taaatttctt cctattaaag aaagtgtaag agaacatagt ggatatttag
    24481 aagttaaaaa ttgtaataaa aacaatttaa aaaatgtatc gattaagata cctaaaggtg
    24541 tattgactct agttactgga gtagcaggag caggtaaaag tacgttgatt aaggatgaat
    24601 ttttaaagca aaatcctagt gctgtactta tagaccaaag ccctgtttca gcaaattcaa
    24661 ggtcgagttt ggcaacatat agtggaatta tgaacaacat aagaagcata ttttcaaaaa
    24721 caaatggcgt aaatgcttct ttattcagtt caaattcaga aggagcttgt gataactgta
    24781 agggttctgg aatagtagaa atgaatcttg cttttatgga gagtataaag agtacctgca
    24841 atgtttgtga aggtaaaaaa tttaaaaaag aagttttaga atataggttt caagggaaga
    24901 atataattga agttcttgaa atgtctgttt tagaggcaat tgagtttttt aatttaaaac
    24961 agattaaaac gaaattacaa tgtattgaaa aaatgggtat tggatacctt actttaggac
    25021 aaactcttga tactttgtct ggaggagagt gtcaaagatt aaagcttgct agtgaattaa
    25081 ataaggaaag ttcagtgtat atattagatg aaccaacaac aggtcttcat atggctgata
    25141 ttgagaattt tataagtata attgaagaga ttgtagataa tggaaatacg gtcataataa
    25201 ttgaacacaa tatagatgta attaaaagag ctgattggat tattgagctg ggacctgaag
    25261 gaggaacaaa aggcgggaga gtaatatttg aaggtattcc aaaacaatta tgtaacaata
    25321 aaatatcatt aacagcaaaa tatatagtat aataaataaa atataataaa attataatga
    25381 tattttaata aatataatgg gtatataaaa tgataattaa acttaacagt aataaataat
    25441 gtgagaaata ttcaaattta attaaataaa gtgtcagaaa tttgtttaaa ttttagtatt
    25501 ttaacggttc tgaccttttt tcttattttt atggagaata tcgaggatgg agtctctaat
    25561 agttactttt ttgtgtctac ttgcaagttt gattaaaaaa tggctataca cacttgtgac
    25621 ttcagtcatg ggaggttcag attataatct taatatataa tttgtgaaat aatttgatga
    25681 cgatttgctg atgtataaac aataaagatt aactacatta aaatttaaat cttgttaagt
    25741 aaaacttata aaaggagaga gatggatgat aaatgatatt ctaaccttat tatctgaaag
    25801 aagtgatttt tttataaagc tatccataga acatttgatg atttctatta tttctataat
    25861 aattgcgatt gttttgggtg gtataattgg tattattgta agtgaatttc ataattcttc
    25921 taaacctata ttgggaacta tcaattttct atacaccatt ccatctattt ctatgctagg
    25981 atttctgata ccattttccg gaattggaaa tactactgct gttattgcac ttaccattta
    26041 tgcattattg ccaatggtta gaaatacata tactggaatt actaatgtgg ataaaaatat
    26101 tcttgaagca gctaggggaa tgggaagtac agattttcag atattgtata aaataaaact
    26161 tccgttagcc ctacctgtta ttatgtctgg tattagaaat atggtgatta tgacaattgc
    26221 attagctggt atcgcttcat ttataggtgc tggaggtcta ggtgtagcca tatatagagg
    26281 aatcacgaca aataacacaa taatgacaat tactggaagt atacttattg ctctattagc
    26341 tttaatattt gattttattt tagggctggt agaaaaattt tttcaacgaa aaagaaaaaa
    26401 gaaaaatagg aaaaaagttt ttgccattct aggaagcctt attcttatag caactatctt
    26461 tacgtcttat ttatttaatc cttcaaagac tcaaactatt catattgcta ctaaacctat
    26521 gactgaacaa tatattcttg gtgagatgtt ggatatttta attgaaaaaa acacaggtct
    26581 aaacgtggaa attacacaag gtgtaggagg gggaacatct aatatccagc cagctatgga
    26641 gaatggagaa tttgacattt atccagagta tacaggtaca ggctggaata tggtacttaa
    26701 gaaaaatgaa ttatatactg aaagtatgtt tagtaaacta cagtcggaat acaaaactaa
    26761 acttaaaatg caatggactg gtatgtatgg tttttctaat agctatgcat tagcagttag
    26821 aaaagaagtt gcagataaat acaatttaaa aaatataacg gacttaaaag atgtatcttc
    26881 taaattgaca tttggagctg aatatgactt ttatgagaga gaggatggat atactccatt
    26941 gtgtaataca tatggactga actttaaaga tacagttgat ttagatattg gattaaaata
    27001 ccaagctatc aatgaaggta agattgacgt aatgcctata tttacaactg atggtcagta
    27061 tagtgtttca gatgttgtag ttctaaaaga tgataaaaat ttctacccat cttatcaatg
    27121 tggaaatgtt gttcgtttgg aagtattaga ggaaaatcca gaactatcaa aggtatttaa
    27181 gatggttgga gatattttga ctgataaaga aatggctaaa atgaattatg acgtagaaaa
    27241 caacaattta gaacctagag aagttgctcg tgagtttctg aataagaaag gtcttttata
    27301 aattggagga aatataatga cacctattat acaatttaaa aatattaaaa aacaatataa
    27361 tgataaaact ataatagata atcttaattt agatatagaa aaaggagagt ttttgactgt
    27421 aattggttcg tctggttctg gtaagacaac actcttaaaa atgattaatg gtctgatttt
    27481 gccagatgga ggaaatattt tgataaacca aacagatatc aaaaacgagg acttaattaa
    27541 attaagaaga agaataggat attgtgtaca gggaagtgtt ctttttcctc atatgactgt
    27601 tgaagaaaat atttcatatg taccaaatct cctaagtaaa aagaataaat tagaagtaaa
    27661 aagtgctgta aacaagtgga tggaaatagt gggattgcca aatgatatga aagtgcgtta
    27721 cccatcagaa ttgtcaggtg gtcagcaaca acgtgtaggg attgcaagag ctttagcttc
    27781 ttctccagaa attttattaa tggatgaacc ttttggtgca gttgatgaga ttacacgaaa
    27841 gcaattacaa aaagagataa aagaaattca taaaaaaaca ggagttacaa ttatctttat
    27901 tacgcatgat atttatgaag ctttgatttt gggaacaaag actttggtat taaatcatgg
    27961 agttgttcaa cagtatgata ctcctgagaa tattttaaat actcctgcta accaatttgt
    28021 agaccagtta ttgaatataa gaaaatctat aatagatgat gataatttaa aagaataaat
    28081 ttaaatttaa aatcaaattg ttgtgataaa aactattgat ttagagctaa cttcaagttg
    28141 tatacttgaa gtggaaaagt tagattaagg tatagaaggg catttagcag ttggctgtag
    28201 acgaggtaac tgctgaaggt gctttcaata aatggctaga acctgtatct gttgaagatt
    28261 ataataaatt gaaataagaa gctcaatata cagagtagat aggcacttca aatagaagtg
    28321 tcttttgtgt gccataaaat aaatcaaaat attagcaaag aatgtgaaaa acaaaataaa
    28381 ataatatgct atctttaaaa taggagggat gctatatgga taacaatttg attaccattg
    28441 aaaaaacttt agattatata gaaaaacatc ttttagatga gatgttagat ttaaatgtaa
    28501 tttctaaaga gataggctat tcaaaatacc atttacatag aatgtttaca tcagttgtcg
    28561 gatttagtgt acataattat atacaaagac gtagacttac tgaagcagcg agaatgctaa
    28621 tttttacaga aaaaccaatt attgagattg ctttaatctc ggggtatgat acacaacgct
    28681 ctttttcaag agggtttaaa aaaatgttta aacgtagtcc taattttttt agaagacatc
    28741 aagatttttt accactacaa ttaaaatttg atattcataa tagaaaaaaa ttacgtggag
    28801 atatggtttt agatgttaaa aaagttaatt gtgcagatat aaatattgtt ggctattctg
    28861 gtaaagtaag aaaaggattt catattattg gaaaatgctg gagggatttg cataaaaata
    28921 aagagatgat agaaaataag gtagatttag gttttttaat tggagttagt gattatagca
    28981 attttaaaga gattgagaat actcctacat ttacatacat tgcaggtgct caagtagcta
    29041 cttttggcaa attacctaat ggaatggaaa aattcgtatt accgaaaagt aattatattg
    29101 tttttacttt tattgggaaa aatgaggata gtatgcaaaa tgttgtagaa tatatctatc
    29161 aagaatggtt ccctaattca agttgccagt ttaatgaaaa taatttatat gactttgtaa
    29221 aatatggaga aaaaactgat gagaatggtt tgagtgaaat tcagttttgg gttccaatca
    29281 tttaaaagaa ggtattatgt ataaagtaga tggatttata taggcaaagt tttacagcag
    29341 tatgtattta taaataattt atagtttgta ggaaagaaat aattttacta taagattatg
    29401 ataaaataca caatactatg acaaaatagt gttaaataat agatttaatt ttgcatagga
    29461 aaagttctat aatggtgtgt attcataaat aatttataat ctgtaggaaa gaaatagttt
    29521 tactataaga ttatgataaa atacacaata ctatgataaa atagtactaa ataatagatt
    29581 taattttgca aaggataagg tgttttaata aaaatgaatg tagaaaacga attacttaaa
    29641 aacctagata gattgcatac aacagagtta ggcgttgtaa gaattaagaa aaatctttct
    29701 ttggagacaa atgatgtagt gaactggtgt aaaactaaaa tagaatctcc aaatgccatt
    29761 attaatagaa agggaaaaaa ctggtatata agtgtatatg attgtattat aacagtaaac
    29821 gctcacagtt atacaattat tacagctcat aaagaaaaga aatgaattgc aaaatacaaa
    29881 ggtcaaaagc attttccact gtttgtagta cctatgaaga agtatataaa ataatattac
    29941 ttttgaataa taatttaaat tttggaggtt gaaaaaatga atgatactgt aaaagaaaaa
    30001 ttggcagagt cactaacttc tgatactact gatattttac cttatttgcc ttatttatta
    30061 caagattttt gggaattagg aagttcacca gaacaaatgt tacaattatt tagaaagcat
    30121 atacctttta atgaggatac aaaagttttg gatttagctt gtggaaaagg tgctgtatct
    30181 gtgaagcttg caaaagagtt gaatatacat atcaaaggta ttgatttgat acctgaattt
    30241 attgattatg ctagaagaaa ggctattgaa tataaggttg atgctttgtg tgattttgaa
    30301 atgaatgatg ctaatagttc tgtaaaaatt gagcatgatt atgattgtgt gatttttgga
    30361 gctgtagggg atattttagg taattataaa gaaactataa gtaagctatt acctacaata
    30421 aaaagtaagg ggttcatttt aattgatgat gcatatgtag tagataaatc tacaaatgaa
    30481 cagcttaatt ttgagagggt gtatcccact tacaatgagt ggtgtatatt gttcaaagaa
    30541 ttaggtctga agctaattga atgtatacca tgtttagaac ttgaaaatga tgttgaagag
    30601 gaaatgaatt ggattataac tcgtgcaaat gagctaatta aaaaatatcc ttctcaaaaa
    30661 gatatgtttg aacaatatgt tattagccaa aaaaatgaat atactgattt acagcaggac
    30721 cttgttggag caacttggat tttacaaaaa gaataagata aatattagac tagataatca
    30781 atgttatagt gaattatccc atgtctagtg aatataaata acataaaaaa ccgtcaagat
    30841 gaatagttta ttcgtgcttg acggttttta gtatttgttg aagtaaaatt ttatttcttt
    30901 agtatatcac ttttagtcaa tccatttgat ttagcttgag tattccattg atgattcccc
    30961 ataagtttat ataggaatct agggaagtta ggtgaaataa aaatagtact tttgttggaa
    31021 tcatctatat gtatattatc actaagtata ttttttgaaa gttcttttaa tgcaattcct
    31081 aaatcttttt taggtccttt acccaaaggt acggattcta gtgaaccaaa catctcccca
    31141 gctccaattc caataccttg aacccatgta aagttgattt ttttacacca atgctctatc
    31201 atttgaattg ccaaatgatt atgttcacct tcattgaatc cacagttaac tattgcatac
    31261 actggaatag gttttttatt ttgtgttttt aaaaattttt cacatttctc taaaaaatga
    31321 agtaaatgag atggaatacc atctacataa agaggagatg cgattattaa tctatcacaa
    31381 ttaagtatgg cattaagagc gtcaggatac ttagatgtgt tatctacttt aaatgtaaaa
    31441 actttattat cattttgaat aagttgtttt aattcagata aaaaatactg tgaattattt
    31501 ttatttactt ttggactacc atttatcatt actatattca tatggattca cctcttatat
    31561 cttgtatatt ttcatagaaa caaacagagt gttcttttat attgaaattt atagcatttc
    31621 catttactaa tttcgtagca gtttcttttt cagcttctgt aatacaatct ccatagaata
    31681 tagcttttaa atttatctgt ttatcatatc tgcttttatg acgcatcata ttatctttta
    31741 ttacaaagta tggaagaata taattaatgc ttttatcaag tacgtttttg acaaaagggc
    31801 taaaccctcc gtaacagcat ctgcttatta taataattcc atcagagtca tttataagtt
    31861 tacccatgtt gctgtaataa tcttttacaa cacattcaga aggagtttta atccagcaac
    31921 caaaacaacc aatacatttg tggatttctt ttgtgtttgg aagtattttt atattgtcat
    31981 caagtttggg taataacttt tctaattctt tgtcagttaa atcatgtatt aaaagcctca
    32041 taaagtccat ctccttttat tatgtatgtt tacttctaaa aattatatct tatagatttt
    32101 tcagtaaatc tttacaccaa ttaataacaa aattataata gtcaactcca taaatcattg
    32161 ttgcatacat atatgtatat tggtcaacac aatgattttc ttctgcatca tttttttgtt
    32221 tacttaattt atttagaagt aattctactt cagttattaa catttttaag tttgtttcaa
    32281 ttatttcttt gggtagatac ttgtaaaaga atatattaac aaggtggtct tgctttgttt
    32341 tagaaaaatt tataggtttc tttaaccatt caagaaatac ttctttacca gtattagtta
    32401 tggaatatag tttttttaat ttgttaccat ctataacttc gtgatagtgt atatatcctt
    32461 ttgtttctaa tcttttaagt gcaggataga tacttccaaa gctggcgtca aaaaagtacg
    32521 aggtactttc tgacattatt tgttttaagt cgtatccact taattctttt tccattaaaa
    32581 atcctaaaat aatgtattct aacatattac ctcctggtat caattagata tatatcgatt
    32641 cgatatattt attattacag ataataaatc ttacgtcaag atgcttttta agataagcta
    32701 aaaagaatta ggagttattg ataaatatgc aaaaaaatta atataaaagg taattaaata
    32761 tcaataaaga tttaaaaata gttaaatcaa agtaagagtc taatatataa aatttatagt
    32821 aactttatgg tttaaatata aacttgtgtg ctattgacaa agtataaaat tagcagtaga
    32881 ataattgcat gagcaaatag attgttgcga acgcaaaaaa aggacaatag atattaaagg
    32941 agagaatatg agagagctat taaaatgggt ttccattata aatagataca atacaaatta
    33001 tattgacagg aaattggcgg atattggaat caataatagc caatattttt atgtattaca
    33061 catatgtaat aatccaggta ttacacagga cactatattt gagaaaattc ttgtgaatcc
    33121 tagtaatata acaagagctt tggcaaattt agaaaaagaa ggctttataa caagagaacc
    33181 aggtgtaaag gataaaagaa catggcattt atatcctaca gaaaaatctt taggatgtta
    33241 tgatgaaata ctaaaaataa caaatgggta tgttgaggag ttgttgagtt catttgagaa
    33301 agaagagcaa gagttgttta tgtcaatgtt aaagaaagtt gcatttttgg ctattgatat
    33361 gaatgaagaa gcaaaattgg aggcgaagga aaatggaaga aaaatataag gagccattgg
    33421 aatatgaaaa ggtttcaaag ttattaacta agtacgcaat tcctagtatt atagcaatgt
    33481 tagtaagtgc tttatataac attgttgacc aaatatttat tgggcaaggt gttggtgtat
    33541 tgggcaatgc tgctacaaat gtcacttttc cactaacaac aatatgtact gcaattgcat
    33601 tattgttagg aattggagga gcgtctaagt gttcattgga attaggtgct aaaaattcag
    33661 aaaaagctac aaaagcagca ggaaattcta tatgcttgat ggctgttttt ggaataagtt
    33721 tatttatagt agtatcaata tttttaacac cactattaaa attctttggc tctacatcag
    33781 aaatactacc ttatgcacac acatatacaa aaattacatc aattggatta ccatttctta
    33841 taatgtccac tggaatgagt aagttgatac ttgcagatgg gagaccgaaa gcttctatgt
    33901 tttgtatgtt aataggagca gttattaata caattttgaa tccattattc atttttgttt
    33961 ttaatatggg aattgctggg tctgctttag caactgttat tgggcaactt atatcttttg
    34021 gaataagtgt tcattatata aagaattttc aacatattaa attacataag aaaagtttta
    34081 aattagatag tataatttat aaacatatat ttgcgctagg ttcaagctca tgttttaatc
    34141 aattagcaat gactgtaaca cagatagtta tgaataatac attggcatat tatggggcta
    34201 ggtcagttta tggaagtgag attccacttg cttgtgtcgg tatcattatt aaagtaaata
    34261 tgatttttat atctataatt attggtatat cacaaggtat gcaaccaatt atagggtata
    34321 attatggggc tgaaaagtat aatcgtgtaa aagaagcata taagtttgca gtgggaagtg
    34381 caactattat atctgttatt gcattcttat gtttccaatt attcccaaga caaattacgt
    34441 ctatatttgg taacggaaat gagacttatt ttatatttgc agaacattat tttagaactt
    34501 tcttgttctt aacatttata aatggtgttc aaatagtatc atcaactttc tttacatcaa
    34561 ttgggaaatc agtgttggga ctttttactt ctttgactcg tcaaatttta tttttaattc
    34621 cattgatagt aattttacca atgtttatgg gaattgatgg agtaatgttt gcaggaccaa
    34681 tagcagatgc agcagcggca atggtatgta tatactttgc agttcatgaa atgaaatcat
    34741 tgactataaa gcaaaataat ttgatgagta accataataa gattgcagag gtataagaca
    34801 atatttaaga agtatagaaa attaatttaa agaagtataa taaactaatt taggaagtat
    34861 agaaaattaa tctaaagaag tataataaac taatttagaa agtatagaaa attaatctaa
    34921 agaagtgtaa taaactaatt taggaagtat agaaaattaa tctaaagaag tgtaataaac
    34981 taatttagga agtatagaaa attaatttaa agaagtataa taaactaatt taggaagtat
    35041 agaaaattaa tttaaagaag tataataaac taattcagga agtatagaaa gctaatctaa
    35101 agaagtatag taaactaatt taggaagtat agaaaattaa tctaaagaag tataataaac
    35161 taatttaaga aatatagaaa attaatttaa agaaatacaa tacattaatt tttaagtaac
    35221 attaaattaa tgtaagtaaa ataatgttca tatgaagatt taaaggtgca ttttctgaag
    35281 ctaagtatat gttgtagagt gttaggtctc tctatcctgt gaagtttaat agctcaagaa
    35341 aatgcactat ttatgatgat tattttgttt tatttccaat tttggaaata actattctaa
    35401 ttaaatctaa aattatacca taaataagaa aagaaagtat agatgctatg taccaataaa
    35461 tcgaaattga ccctgtaatt gttctacatg ggatttgcat acctgaatcc ataaaaacaa
    35521 aaaaactatc aactctggaa ataatagaca aaataggatt taaacctatt agaacaatac
    35581 tttttgagtc ttgaccaatt tgatgcatat aaatctcaaa taatgcaatt aaaaaaaacc
    35641 aaaatgtaaa agatttaata atttttttca tcaaaatacc tcacataata taaattctgt
    35701 ttgcactatt tgcttactac aactatttat ctccattcag tcacatcact taattgtaat
    35761 ctaggtcttc ttgatggttc ttcatcagga taacccaaag atattgctgc cactaattga
    35821 ctatctgtat ttaaccattc acataattca cgatatgcaa agtatacatc acaaatccaa
    35881 agactaccta gacctaattc cacagctgta agcgacatat tctgaattgc agctccaatt
    35941 gattgcatgt ttgccatttc atagaatcgt tcttcagggg atagcttttc taaaggtgat
    36001 ttacctaata tatttaaaat aaaaattgtt actggagctt gtttcatgat ttcaactgtg
    36061 taatttgcac cagcgatatg ttgacgactt cctggaagaa gcccattatc attaatttca
    36121 ttttgaatac ctttgctcat ggctttaagc atagattctt tttccttttc agtgatgaca
    36181 acaaaacgcc atggttgcct gtttttagat gaaggtgcat ttattccagc ttcaattatt
    36241 ttctctatag tttcatgtga aatgctttga tttttatatt ttctgatact tcgtcttttt
    36301 gatatagaat cacttatcat tttaagtaac ctccgtttat tttttggaaa aatctattta
    36361 atttttattt tctattttaa ttattttagc attaatcaga aaaaaagtca ttgattttag
    36421 tatacaatta ttaatgatta tattaagaat tgtatcaaaa agtatgtgat tatactaagg
    36481 gattatatta aacattatat ttaaaattgt atgaaaggtt gtatttaata ttatattgag
    36541 agatatatat attaggattt atatatattc agatttatta ttatattgag ccttatatta
    36601 aattaaggac tataatttga aaataagcta taaaaactta atattgtttt gttcagagat
    36661 aaaaaaagaa tactttaggt gatttttatt aaaaattaag agtgataaaa ttatatactt
    36721 tataaatgta aatatgacga ataaaaatga taaatataat aatatatata tttacattag
    36781 gagttttcta tactataatt atttaaaact aaatataaat gttggaatta tttaggactt
    36841 gaaattgtct aaaaataaat acaagtgatg aagaggtgat gtgatgagat tagatatgga
    36901 tagtatgtta tatgtactaa tttatatgac attattggta tctatcattg gaagtatatt
    36961 ttatttttgt aaagacctct taaatcataa aattaagtat gttttaataa gagacatatt
    37021 tgtaaataga attacatatt ctgaagaacg actgcctaaa cagtatatag tttttcagaa
    37081 atatgatatt tggaggtatt gtagtttgtt ttaatttgaa atgaatctat tataaattct
    37141 aaagtttaaa aataaaaagg agagaataaa atggatttca tttcaagtat attgcaagga
    37201 ttattaagta tattatttaa ttttacaggt gattttggaa tttctattgt acttataact
    37261 ttaatagtta aattagtact tatgccacta tcattaaaac aaagattttc tgtaaaaaaa
    37321 cagcaagaat tagctgaaaa aatggaatat ataaaagaaa agtataagaa tgatactaaa
    37381 gaattggaaa agcaaataca agtaagttct gtagaaagta tgaagagtat gctgggatgt
    37441 cttatagttt tggttcaaat gccagtagta tatgctttat atcatgtatg tttagatatg
    37501 acaaaggaat ttacaacaat tataattcca tggattgcta atttaggtac atttgataat
    37561 ttgtttatat taccttgtat atatacatta attatgttag cttcaaattt agtgaattat
    37621 ataccatatt taaaaataaa ttctcaagta aagtttaaca aacaaatggc tgtggtgact
    37681 accataacaa gtcttatact aactgttaga actccagtag ccataggtct gtactttata
    37741 acaagtgcaa tttattcatt aattgaagat atttgcttta gaatatattt taatcgaaaa
    37801 aatagaatag tgacaaaata atataattat tattagaaat attttagcct gctaacatag
    37861 aaaaagttag taggctattt ttatctatga tatcaattcc attaagaata gtctaaaaaa
    37921 tactatcaaa atgctataaa aaatactata aaaaaatagt tgaaaaataa ataaattaat
    37981 ataaactaaa ataaagccta caaaaaagag gtgataaata gaaatggcta aaatactagt
    38041 tgtagaagat gaaaaaagaa tgcaaaatat tattgtagaa tatatgcaaa agggaggata
    38101 tacttgtata actgctgatg atggagtcga ggcacttaca atattaaaga gcaacaatat
    38161 agatttaatg atattggata ttatgatgcc gtatttagat ggattttcag tgtgtagagt
    38221 ttcacgtgaa atgactaata tacctattat tatattgaca gctaaaggtg aagaggagga
    38281 taaattaaag ggttatgaat atggcgcaga tgattatata acaaaaccat ttagcccaaa
    38341 agtactttta gcaaaagtta atgctttgtt acgtagatac actactgata ttcccaaaaa
    38401 ttcattgagt ttaggaaaga tttttattat ggtagcatca agacaagtgt atgtagaaga
    38461 taaattgatt gatttaacat ataaagaatt tgaattattg cgtttattta tggaaaaccc
    38521 taatcaagtt ttttccagag agaaactttt aaattgtata tggggatatg attttgaagg
    38581 aaacacacga actgtagata cacatataaa aaccttacgc aaaaagcttg gtagtgaagg
    38641 acaccatata gttacattaa ttcgttcagg atataagttt gaggttaagg aatgaatagt
    38701 ttaagaaaga ttatagaaaa actgaaaaat gtagatattt caaattggat taaacaaaat
    38761 tttggactat attcagttag aaaaaaagtg tttttacttt ctaaattatc aggagcgtta
    38821 attatattat tttatctggt tgttgaagaa ttttcgataa actctaaatt tgaattttgg
    38881 atttggttta taatactggt tatatttatt atgagtattg atttcttatt gggaaaattt
    38941 atttcagaac caatcacatc tataaataaa tctgcaaaaa gtatgtccca acttgatttt
    39001 tctaatccat gtactgtaaa tactaatgat gaatttggag aactttctag gagcctgaat
    39061 acaatgtcta caaatctaca acaggcatta tcagacctag aaagtgcaaa tattcaactt
    39121 gaaaaggatg taaataagga aagaatgcta ttggaacaaa gaaaggagtt ggtagataca
    39181 atttcacatg aaatgaagac tccacttggc attatacgtg cgtatacaga ggggcttata
    39241 gatgaagttg atgaagaaaa aaagaaaaat tatatgaatg ttataataga agaaactgat
    39301 agaatgaaca atatgattgt atcattatta gacttatctg cattggaagc aggagtttct
    39361 aaacttaacc cagagcgttt tgattttata gagtttgttg aaactgtggc aggtcgtctt
    39421 ttaattgata taccagatgc caatttttat tttacatatg atttgccaga gtatgaagtt
    39481 tttgtagtgg cagataaaat gagaatggaa caagtagtag agaatctagt tattaatgca
    39541 aagaagcatg ttgtatataa tggtaattta gatttatcga ttacatgtga aaatggcttg
    39601 cttttatttg aaatttataa tgatggtagg tttatagagc aagatgagat ttcaaagatt
    39661 tggtctaagt tttatcgtag tgttcaatct cagcgtacag gaggttcagg tctagggctt
    39721 gcaattgttt cacaaatact tacaatgcaa gggttagaat atggagtgaa taatcgtgat
    39781 agaggagtag agttttattt tatgattcca attgatgaat aatttagtat taatttataa
    39841 attataagta tctgatgtaa aatattttta tttgtatacg taagtattta aagagaataa
    39901 aataaaaaaa cttaatgaaa aagcttaatg aaaaagtcta ataaaaagct taatgaaaag
    39961 cttaataaaa agtcttgttt tcctgatgaa aacaagattt tttattaagc tttttattat
    40021 ttcacttcga tttcacaaga gagacactct gatttcacca aatagaaata aaataggtta
    40081 aataaattaa aaaatagaag cgtaattaaa taaggttaca agggggagta cttatgaaat
    40141 ggtatacatg gttgactatt atattgataa tattgctttc tattccgctt aaaattaaat
    40201 ttataaaatg gtgggataga cgacaaaaaa atgataaagg aggttatgat agatgataaa
    40261 agtaagagag ttaaaatttt cttatggaaa agataaacag atattgcatg gacttaattt
    40321 tgaagtaaaa gaaggagaaa tctttggatt ccttggacct aatggttcag gaaaatccac
    40381 aacacagaaa atcttaaatg gtgttttaaa aggttacaat ggtcacgtat ccatttttgg
    40441 taaggaagtt aaagcataca cagaatcttt atatcaaaag attggtgttt tatttgaatt
    40501 tccttattta tataccaatt taagtgcaat tgataattta gaatattttt cgtcttttta
    40561 tcctaaaaat caaaggagag acatatatga actcttagat ttgttagagt ttaagaaaga
    40621 gtttataaat aagcctgtat catcctactc aaaaggtatg aagcaacgta ttagcatggc
    40681 aagagcattg gtaagtaatc caaagttgtt atttttagat gagcctacta gtggacttga
    40741 cccatctgga gctgtactat ttcgtaagat tattgaagaa gaacgaaaaa aaggaacaac
    40801 tatctttttg actactcata atatgctaga tgcagattta atgtgtaaca atgtggcttt
    40861 tattgcagat ggaaagatta tggtaataga taaacccaaa aatttaaaaa tgaaaaatag
    40921 caataataaa gttgaagtgg aatttgtata taatggaaat cgagatattg aaattgtaga
    40981 tatacaagag ttagaatctg gaataacttt taaatatgat gaaatcttaa gtgtacattc
    41041 aaaagaacct acactagaag aagtttttat taaatacaca ggaaggatgt tagtgtaatg
    41101 tattctaaat tttttacctt agtaaaaaaa gatttttgga tgatgattta tggtaaattt
    41161 tttgtgctga cacttggctc tctcatactt tattcgtgtt atattaattt tggttatgta
    41221 aagtttatgg atgaagatag ttatcacaat aatgtatatc tatataatcc agagaatata
    41281 agcatgagtg catctccatt aattaatcaa gtttcttcta taggtgaatt aaaagcaaaa
    41341 cttgatgaag atacaagtgc agtttgtatt gatatgagtt ccagtaagcc gaaagtaatt
    41401 ttacatgaaa gtattaaagg agttgacaat tatagagctg actatgcatt gtcattatta
    41461 tcatcagaaa aagaccataa tagcaaaata tcagacaaca atgcaataat tcaaattaat
    41521 gataaggata catctgagat aaaacaaaga aaagacatga cttgtgagat tttattcttt
    41581 gaaattgtag ctattggatt tttagggatt gcctctttat tatttaaaga aaagcagatg
    41641 ggagtaatgc gtattactgg tattttacct gtaaaaagaa gtctttttat attatcaaag
    41701 atatttgctt tttttatatg tgacctatgt tttacagttc ttttagtagt atttaatatt
    41761 ggatttttag aaggaataaa aatacttcca caagtattag ttcaagctag tattttatca
    41821 attattatgt ctttgattgg aataggatgc tcaatgttat tgagagattt taagcaattt
    41881 tctcttatat atcttgtggt tgctgtattc ataactacac ctatatttct atctgcaaat
    41941 acatcttttg aaatagattg gattaaatat catcccttct atcatgttta tagtcagctt
    42001 aaaaatgcgt ttttcatgaa tttttcaaaa gaattagttt attttgtagt gtgttctttg
    42061 acaataatag ttctattttt acttgtaaaa tatattttta ataaagaatt ggttagggag
    42121 ggataatctt gataggatta cgttaccagt taaagagtat aaaaaaagat aaaatgtgta
    42181 taatttcctt ctttttacca gttgttatgg cgattttaat aaattttatg ggaacaattg
    42241 atatatcttc attaggagag atacgttttg gtatagtgaa ggatacactt cctgtacaaa
    42301 cagagcagtg gttaaagaag tatggtatgg taagtgtata tgacacaaaa atgcatttaa
    42361 tacgtgaaat taaggatatt aaaacggaca caattggagt tgttagagat ggtaaaggaa
    42421 taaaaactgt gttttatgga aatgagatta atgctataaa aaatgttgga aagacattgc
    42481 cagagatgtt tagactaaag ggtgatttaa aagatgttga ggttacaata ttgcctaaag
    42541 atagtatttt aaaagagttt caaaatgttt ttattgctat gattttaatt actgctatgt
    42601 ttatgggatg cacctttaat gcaatgaata ttatatcgga aaaagaagat ggaatatcat
    42661 ttataaatga agttttgcca cagagtagaa gtcagtatat tatacaaaaa gtatttttgg
    42721 gtcttttatg tgggtgttta tcttcaatga taactgtatt tatatgtttg gatatttcaa
    42781 tattagatat gataatgatg ttgttactcg ttgtattttc agcatttatt tcatcactta
    42841 taggtttatt tattggaaag ttgtcagaag gtcttatggt aggaattgtt tatattaaaa
    42901 tagtaatgat tttatttata ggtactcctt tgttaatata tcttctaggg gttaatacca
    42961 gtggtatagg gaatttatgc tatataatgc cttcagttgc tacatttaat ggtattatgg
    43021 agattattaa tggtaatgtc attattatca aagatattgt aattttggct gtacattgtg
    43081 tagtatggtt tatgatatat attattttag ataaaaaaag aaagttatct tttagtagat
    43141 aactcagtat aattataatt gggacaattt aataggtgat ttaatatact ttgtatagtg
    43201 taatttatgt agtgcaattt gtatacttta atttatgtag tgtaatagtt agttttattt
    43261 tataattatt caatataatt tagtaagaag ttcagtacaa ttagagctac ttagtggaaa
    43321 acttaatagg tacttaaact atataaatac tttattttcc tccatttgta ctataaattt
    43381 aatttatgat ataaatggag gtattattat atgatttgat aaatttcatc attataacct
    43441 acaagtaaag gtattattat ataaagttaa taaagatagt atcaaaatat tatttgctat
    43501 aaagagaggg actcaaaata aagataaacc tatttttcaa tgttgaaatg ataaaatata
    43561 tttgatttca tataaaaaat tttcttcata aattaaaaag tccattttaa gccccttcat
    43621 ttttaaccag ataaatcgag ttaaactatt taaatatatt actcggattc atttgactta
    43681 gatattcctt gcttgtaaaa ttgttttgaa taggggatag ccaaagcaaa aaataaaagt
    43741 ataatccctg ctatgattat taaattatta atagaaatta catctgccat tggtccgaaa
    43801 atcatcatac caagaggaat aaaaccagta tatataataa taggtaagct aagaactcta
    43861 cctagcattt gtggtgctac atgctcttgc aacatagtca tagctgatgc ttgaatgatt
    43921 ggaattgaaa aattcgtaaa aaacataaat ataaaaaatt gccaagcttg tgttacaaga
    43981 cctagaataa ttgaaaaaat agcataggat aatattgcta gaaaaaaggt cttatttcta
    44041 tttttaaaac caccaaaaac tcctataatc aatccaccta aaaccatacc taaaaatcca
    44101 atcatttcaa taatagacag gtatatataa cccttgccaa atgttcgttc aataagaagt
    44161 cctataagaa atcctgatgg aacacaaaga agcatgaatg ctccataagt aaaaagcact
    44221 tttctaatga acttatctga aaaacagtac tttatccctg ataccatatc tgcaaaaaat
    44281 gagacttttt cagtttgttt tggtatatca tgtttaggaa ttttgatgaa tattaataat
    44341 acaatagcaa taattgcagt aaatacatca attaaaagaa cttgatttat tttattacca
    44401 aatccaagta ttgcagcagc tacaatagga actataaatt gtactataga ctgtagacta
    44461 ctatttatac cattaaaacg cattaaatgt tcttctggta caagttgagg aatcattgcg
    44521 tttacagcag gtgtttgtac accacttcct agtgaacgta taacagatat tactgatatg
    44581 gctattaatt cacttgttgt gccatttgat gacatcataa atagaattag aactaatgta
    44641 gatatagcaa ttgttgaatc tgatacaatt atgagtacct ttcgattgta gtagtctgcc
    44701 catacaccag caaaaaaaga aattatcatt tgaggtataa aggagcatac agttaaaact
    44761 gttacccata cacctgatga tgtctgaagt gtgacatacc atatcattgc catttgtaca
    44821 agtgatgagc caaataagga aatatattga cttgctaaaa aaagaatgac ttttttcttc
    44881 catgtagaat tagtattttt attttccatc ctattcctcc tttgatttgt gtgttgaatt
    44941 tttcttgctc ttaaggataa cacacaaatc aaagtctgga gttagagtgg agggctagga
    45001 aaattgtttt ttcataattt gaagatgaga tttcatggtt tttgcattat gttcagcttc
    45061 tttcaatgaa gttatcagtt tgtcacacac tgagataatt tcgtcatcat cttttggagt
    45121 gtcaaggaca gttttaatat tagtattagg actagaagat aaagcattta acattcgtaa
    45181 aatagctgaa agagaatagt ttgcacaacg aagtgcgctt ataattttaa gtcgttttat
    45241 atcttcatca gtatatacac gataaccatt ttgttttctt tttactttta acaaaccatt
    45301 catttcccaa tttcttaaag tatctattgt aacgtttaag tgttctgcag tttcttttct
    45361 agttaaaaag agtttatttg tttctggagt atttccattt aaaatctgtg caacaatagt
    45421 aagtgcttcc tcggcattag atttttctat ttctaattgt tgcaagtatt gatttacaag
    45481 actaatagcc ttatcaaagt ccctattcgc tgatgttctt acaatctcaa gggcatcttt
    45541 tcttaatccc ctttgtacca cttcaatttt caaggctgta cgagcaaatc taaattgttc
    45601 tatatgaaaa tcattaaaga tacgataacc attggtatta cgcttaggtt taggtattaa
    45661 gtttagttct tcatataaac gtactgtatt aggatgtaca ccaattaaat ctgctacctc
    45721 tgatgtcgtg taagtgtcca ttagtattca actcctttta gatatatagt attagtcata
    45781 ataacaccaa acaaaagtct ggtgttataa tggagggttt ggctatctaa gagtaattag
    45841 tttatgaaag agtaattagt ttatgaaaga gtaattagtt tatgaaagag taattaatct
    45901 attatagaag taagtatata tttttcaatg aactcccatc tatcacgagg tttaaacact
    45961 attttagatg gtatggctat tactaagtca tattgtggaa tacaacaaat agcatttcct
    46021 ccagttccca ttgctgaata ccacaaaaca ccatcttttt tacatagcca ccacagataa
    46081 ccgtattcat tactattcat tttaactgat tcttcaatcc acgatttaga tataatacgt
    46141 ttattattcc aaataccatc atttaaatac agaaaaccaa atcgcaacat atctctagca
    46201 ctcaatgtaa gtccccagcc acctatagaa taaccctgtc tatcttttgc ccaaccctta
    46261 agattttttc caaagaaatc ttcaaaacca aaatctttca tatcataatc tggtataact
    46321 ttcataccaa taggtttaaa taagtactca ttagcaaatt cacgagcaga ttttccagta
    46381 gtttttgtta taatagctga aagtaggtgc gttccagctg aagaatattt gaaagtacca
    46441 atttcgcctt tttgaccaag ttgattcaag gtatatttta tccaatcttt ttgtttgcaa
    46501 agtctttcta aagactcagt catattttta aaagggtatg gtgcagtcat tgtaagtagg
    46561 tgacgtatag ttactgcttt tttacatatt tcagaaggac tacaagtata ttcaggaaaa
    46621 aaatcaacaa ccttttggtc aacatctttt atatatcctt tatctattgc aatacctatt
    46681 aaggctgata taatactttt tgtaactgat gcaacatgaa aagtatcatc agcattatat
    46741 ccattatagt acttttcaaa gacaattttt ccttttcttg caataattat accatttata
    46801 ttgctatatt gtgagattat taaaggttca agttgtgaaa gcttttctga actcatacca
    46861 acacttgaag ggtctacttt ttcaaaaatt aagtctaagc aattgttttt attcattaaa
    46921 gatacctccc tgttatagat tttggatttt cttttagagt ttttggagaa ccttctgcaa
    46981 ttatataacc tcctttgtca ccaccttctg gaccaagctc aacaatccag tcacaaacat
    47041 ttaatacatc tatatcatgt tcaacaacaa ttacagaatt tccattttca accaattcat
    47101 ctaataattg aatcaactta gaagtatcat atagacttag accagtagtt ggctcatcca
    47161 atacataaag gatattacca tttcgttttt taccaatttc ttttgcaagt ttgattcttt
    47221 gggattcacc accacttaaa gtcggtgtag gttggcctaa ttttatatac cccataccta
    47281 tttgttctaa tacatttaag tgtgaaacaa tatttggaat atctttgaag aaatgtacag
    47341 attcagaaac actcatattt aaaatatcat gtatattttt atttttatat ttaatagata
    47401 aagattcatc attaaatctt tttccctgac attcactgca tatatggtct atacttagat
    47461 tatttcccaa ccagaccttt tcatatccac taccactaca tttaggacaa gcccctttgg
    47521 agttaaatga gaaatgacca gctgtaaatc cttgttctaa cgattctggc tgacctgcaa
    47581 atagtgtacg tatcttatcc catataccaa tataagaagc aggagttgag ttcatatttt
    47641 tgcctatagg agattgagat atctctgaat atccagaaat atgtttagta ccaatcagtc
    47701 tatctgcaat agtttcaaca actgcataat cgtcttcctc acctatttca ctctctgaag
    47761 aatttatttg attattgata gtatggttat taaattggct tctaagaaga ggaagtaggg
    47821 tgtctgatat aagtgaactc ttgccactac ctgattttcc agatattcca accatagcac
    47881 ccaaaggtaa tgatacagtt acatttttaa gattatttgt atttgcattt tgaatagtta
    47941 tacaaggtat tttatcagta tgtgtaatgt ttttattgct tgttctatta ggcattggat
    48001 attttccaga tagatactgt ccagtaagtg atttgtcgga ttgaagtaga ccttctaaat
    48061 ctccttgata tactaattga ccaccttcaa caccagcttt tggaccaata tcaataatat
    48121 gttctgccat ttcaattgtg tttttatcat gctcaactac tatgaccgta ttgcctaaat
    48181 ctttaagttt ctttagtgat tttaagatgt ctattttttc tgattcatgc aatccagctg
    48241 ttggttcatc aagcacataa attaatgagt ccatctctga atcgagatgt gaatttaaaa
    48301 atagtctttg catttcccca ccactcaaag ttgacatttc tcggtataag gatagatgac
    48361 ctaatcgtga ttctattaaa tgttgagttt tggataaaat atcatttaca agatttgtac
    48421 caaatgtgtt taaattacct tgatttatta agagtttaag gaaatcatca atttctaaaa
    48481 tcgtcatttt tccaagttct ccaatatgtt ttccgtttaa aagtactcta cgtgcttctt
    48541 caccaatttt aaaaccattg caatctgaac aggcagtcat agtataaact ccatttaaat
    48601 cttcgcccct tttgtaacga ttgtgaaata cctttgataa agaggaactt tttttaccat
    48661 tttcataatg accatagagt acttcatttc ttatttcttc aggtagttgt aagaattgta
    48721 tgtctaaata atcattgaat tttttagaaa atactctcaa atatccaggt gtaatctttg
    48781 ctctatctaa gacttgtttt agggtatcat gcttatcaag gactaatttt tcaatattaa
    48841 tctcaaaata tgcaccatgt ccagagcact tcatacacat tccatctgaa gagttgtatg
    48901 agaaataact tggtcttaat cgttcttcct catatccaca attattgcaa attagattat
    48961 cgcttacagg agtatcacac atagtacaca ttatttgacc ttccactgaa tacaatagtg
    49021 taagcatgtt gagaatattg gttcttgtgc ctactgttga acgaggattg ctctggcgaa
    49081 taatattttg ttgaacagct atagtgggag ctaaaccttg aatattatca aacttatctt
    49141 cactatcaat acctgcaagt atacctaaag attgcagata ttgtttacgc ccttcctcaa
    49201 atacaatgtc aaacataagg ctagacttac ctgagccact gacacctgtt gcaacaacaa
    49261 gcttatcttt tggaatagaa acatctatat ttttaagatt gtgtatcttt gctccattaa
    49321 tttttatttc tttcattggt tcacctcatt ttatcaattt tatcaaaccg taaaataggg
    49381 atatattaat ccttaataca agaatagatt aggtgaggtt attaaaaagg ttctataggt
    49441 aaatatatat cgaccaagtg tctattttga gggtgattgt gtgggttgtt aagatatact
    49501 tcaaaaggga aggaggcacg tagcttataa ttaccatttg atagccattc attatacata
    49561 aaatcccacg catcactata ttcagatttt gaaatatcaa aatgtcccac aagatatttt
    49621 ccagaaggta ttatcatatt gccaagattg tcattctctt tgacaacaat gttatctgga
    49681 atggtcatgc aaatactagt ccttaattga tgctcctgtg taaattgtgg attatcatga
    49741 taaatggcta atatttgtgt gttttcaagt ccaagtagat tctgctcact tgcatatgtg
    49801 aataaccgtt ctaaaagttt tgggaaagta ctggttagat taccatatga accagtatat
    49861 ctagtgtaaa tagtattcat attatcaagt tctagaattt caatttcacc tttaacctct
    49921 ctagtattct tacatttagg ttttgatatg cttctattgt actgagaaat tttatatggt
    49981 tctttgcaat tcttgctata attgtttcta tattttatag ggcttatttt atagtaattt
    50041 ttaaatgctc tcgagaaaac tgctgaatca gtaaagccga agtagtgtgc aatatcagta
    50101 acagtcatgt cagttctatg aataagaaaa gcagttgcat tttctagttt tagcctattt
    50161 acatattgtg ccaaagtttc tttttctatt gctttgaaga ttctatgaaa atgaaatttt
    50221 gaaaaacctg ctatattaga aagttcatca agagaaagag gttcatgtaa atgttcttct
    50281 atatagtctt gcactttgca aatacgattt agatattctt ttttactttt agcatttgtc
    50341 atatatagcc ctccttattg tgtaaaatgt gtatcaatta atttatagca atatagtaat
    50401 aaaattttat gtttttgtaa tttatgataa ataagatagc gtttaatttt ttataattga
    50461 taaaagatat aagatgcctt atatttgtct ttgcatataa gtatagtctt cgtaataatt
    50521 agtataccat agtgatttat ttttaattgt gtatttatat aaatacacaa cttatgatat
    50581 ggacgaatta ttatgcaaat aagctgtaat taaataaatt gcaatataaa ccagttgaaa
    50641 cataagttag ggaaatatta tcaaagttat tacttagcat aagagtatag atggaataaa
    50701 ataagattaa aaaattacat actaaattta ataaaatttt tatattaaaa ataatattaa
    50761 gtttattgtt taaataaaaa agttaaatct acactattaa cttattatac ttaaaacttt
    50821 aaaatgaaaa tatcaaagaa tactttttaa taaaaataat catttaataa gttatttaaa
    50881 aatctaaaaa ctttacaaca aattatatat ttaaattgga ggagtgggaa tatgagtaat
    50941 agtttttatc aattaaattc agcagtatta tattttaatg aaaaaagaga tgtaaataga
    51001 ataaggttta atcactatgt aatgagaaaa gaaaatatac aaagattaaa aggaactctg
    51061 ccaagaggac aatttatgat gacagtaagg aaagctgcat ctgaccttga tgtatctata
    51121 tctacaataa gtagacttgt aaatgaattt atagatttag gtatattgag attaataagt
    51181 aggggagtaa agggaaattg ttgttctgta tatagttatg tttgttctga aagtagtaat
    51241 gcagaaattg taacaaagaa tggtgatatt ttcaaaaata tagagaaata cattgatgca
    51301 actattaaca ataaccaaaa aacaatgaaa tataaacata gaaatgagtt gtttaagaac
    51361 agtaatacca acatatacag ccgtataaat caagagagta tagacaaaga ttatgatttg
    51421 ataattcata ctgggtatga aacagaaaat gagacaaaga aaaaagaatt attaaaaaat
    51481 aatttaaata aaaagaattt aaataaaaat acctttgaaa attcggatga agatttgact
    51541 gaagattcta cttacaaaaa tccagaaagc atacatgaaa ttattataag aaaattaaat
    51601 agtgaatcag gaaaaaattt taaagctgat ttgagtataa ctaaggcact tatagataaa
    51661 agattaaaag aagggtatag tttagaagat ttttacaagg ttatagaggc aaaggtaaga
    51721 agatggagat atacagatat ggaaatatat atagaaccaa caattctgtt tgggtatgaa
    51781 tttgagtcgt atttaaatga ggagagttct ttatctgctt gtaattatgg tgatatgtgt
    51841 tatgaagata tgtattgaga tatttattaa gatattagtt gctttttagt tgtttaaaat
    51901 atgtttatgt ataaatagtg tattaaaatg gagttgtctc aaaatagaga gaagtctctt
    51961 cttaattgtt taaatgatga aaatatattt gatttaatac aaaggagagt gctttatgag
    52021 ttagaagatt tattttgaga cactcacttt ttttaatata ctggagaaat ataacccatt
    52081 ttacaagagt gcatagatat atataatggc ataatgtgga tttaaattaa aaaaataaaa
    52141 taaagccata aatattgaaa atttcaatat ttatggcttt attgcttgta ataattaata
    52201 gaatatatat tttttattaa tcatctattt atatttttta ttaatcatct atttcaaatt
    52261 ctaatatttt accagtaatt gcattaattg ttatctcata ttcagttttt ccttttatta
    52321 tttcaccttc atattctttg tcatcttcat catacttaaa ttttactatt ttcccaccag
    52381 gcactttatc tagcattatt gatttagctt tttcagcact aataatagaa ctgttgtcat
    52441 tagtattaga gttattctta tcattatcat caaagtcatc atcagaatca ttgtccatgt
    52501 caatatctac aattcttcca tcaaatgcac ttatctctaa ttcatatgtt ttcttatttt
    52561 ttattacttt agcctcatat tcgttatctt cagcatcata tttacaatag attaaattac
    52621 cattaggaat agcatctaat gctatagact tagctttatc caatgatata ttttgtgtac
    52681 ctaaattatt atcatttaag tcatcatctt tttcaatttc tattatttta ccagagtagg
    52741 catcaatttc tatctcatat aggatattat cctttataac tttgcagtca tattcattat
    52801 catcttcatc ataataacaa actaaaatat tgcttcctgg aagagcttgt tttaatattt
    52861 ctttagcctg tattaaagat atttttttag ttttatttct tatgttcaca ttttttagtt
    52921 ttaaaatatc ttcaaatgct ttttgattat atcctcctcc tacttgtgtt atttcatcta
    52981 tatctttatt tttaataaat tctttttgac tatttacaag gctaccatta gatatcatta
    53041 taggagaatt ttctttagca gctagtactc ctattgataa tgaatctact aatgcatttt
    53101 cttggttaat accatcttta gctacaaata cattatttat ttttttatct ttataaaatt
    53161 tatcaataat ttttgcatta gtattgtttc tatctgaacc actgattctt tctctgtttg
    53221 gatatttctt tactgtattg tctgataaaa tcttatttcc tccaactatg taagattttt
    53281 ttatagacct attgtttaag aaatttatac tactatcatt gctgttttca tctgatacta
    53341 atattatagg catattatgt attgctgctg gagaagctat actaactgca tcagatagtc
    53401 cctttagtcc atttacaact gcaacatttt ctatcttttt tatcttatct atttctttaa
    53461 gtacatttgt agacatttca tatatattgt ttcctactat tttatttatt tttatgttaa
    53521 gtgattttat ttcattttct actttagaag aaatgctatt tccactatct acaatgtaca
    53581 cattatctac accaagcctt ttaagctcag ccttagttga attttcaata ctgttgttgt
    53641 ttactaaaag tataggtgca ttctttagct tagcaaatgg atttgcacaa agcgcacttt
    53701 gaatagaatt accattaact ataatggctg tttttgattg aacccatccc aatttactta
    53761 cttctactgc tgtttcatat cttgttttac ctattaatct ttcttgcttt gtagtattgt
    53821 ctgcaaaaat tgctgaagaa ctagaaaaaa acatcatacc tgatattaat atagctaaat
    53881 ttttcttatt catattttta cctcacaatc tttaaaaatt tgttatttag catacttaat
    53941 aaaatataat cttaaaatca aattgatact gagtttgaag ttacaaaatc aacaaataag
    54001 atttctttaa tacaaaattt tcctttttat atttaacatt gtatcacaaa tataaaaagg
    54061 aaaaaacttt ttaaaaaggg tatacactat tcatttttta tcttataaat aagtctttat
    54121 cactgtttta tatattttaa aatagacaca agacctattt ctaaatcttt tataaatatt
    54181 ttaggtgaaa tttcttttta aacatatcta aaaagtattt gtagtaatat taatggactg
    54241 aatttcttaa agtatatatt tctttacatg ttggagtttg tgaagtttga gaattggagg
    54301 gtgaaagaaa catgtaatgg attaatatta aagaactgta tttttataat atttgtctta
    54361 aaaataaaaa aatctattga cttgaagtta actccaagta gtaaagtata attatacaag
    54421 aattatatac ttgtaagaat agttaaagta gagagaaaaa acaaacaagt tttaaagggg
    54481 gaagtaaaac aatggaggca aaaaaattag gatttggatt aatgcgttta ccaataaaag
    54541 atgaaaatga tgttacaact attgatatgg aacatttaaa taaaatggta gacacttttt
    54601 tagaaagggg atttacatat tttgatacgg cctatgtgta tcacatggga aaaagtgaga
    54661 tagcacttag agaatctcta gtaaaaagac acaaaagaga gagttttact atagctacaa
    54721 aacttccatt aatggcttta aagaaaaaag aagagcaaga aaccattttt aatgagcaat
    54781 tagaaaaatg tggtgtagac tattttgact actatctttt acacaatata ggcgtgtcac
    54841 attatgaagt agctaaaaaa tttgatagct ttaagtttat tgaagaaaag aaaaaagaag
    54901 gaaaaataaa gaatattggt ttttcttttc atgatagtgc agaattattg gataaagtct
    54961 tgagtgagca tccagaagta gacttcgtgc aattacagat taattattta gattgggata
    55021 atgaaagcat acaatctaga aaatgctacg aggtggcaga gaagcataat aagcctgtaa
    55081 ttgttatgga gccagtaaaa ggaggtacac ttgcaaagat accagaaaaa gcagagaaat
    55141 tattgaatga ctacaatcca gatatgtcaa tttcatcttg ggcaatacgt tttgcagcaa
    55201 gtaaagataa tgttatgatg gtcttaagtg ggatgtcaaa tatggaacaa ttattagaca
    55261 atacaggata tatgcaaaat ttcaaaccat tcgtacaaga ggaatataat attatagatg
    55321 aagcagtaga gattatcaac gaatcaattt taattccttg tactgcctgt cagtattgtg
    55381 tagaaggctg tccaaaaaat atcgctattc caaactattt tgcgttgtac aatgcagaaa
    55441 aacaagctct taatactgga ttttcaacac agatggtcta ctataataat tatactaaaa
    55501 cttatggaaa ggcctcagat tgtattgaat gtaaacaatg tgaagaaagc tgtcctcaac
    55561 acattaaaat tatagatgct ttaaagaatg tagcagaaac ctttgagaaa taattcaatc
    55621 tatacaatat caagaggaga agatatgtat gacgatttca gaagttagta aaaaatacga
    55681 gctttcagcg gatactttac gatattatga acgaattggt ttaataccac ctgtaaatag
    55741 aaataaaagt ggaattaggt cttttacaga agaagattgt gagtgggtta atttcataaa
    55801 gtgtatgaga ggtgcaggtc tttctattga gacattaatt gagtatgtag ctatgtttca
    55861 acaagggagc agtactatca aagctagaaa agaactttta atagagcaga gaaaccaact
    55921 agcaaaaaga atagaagaaa tgcaaaaaac tttggaacga ttaaatttta agattgatag
    55981 atatgaagaa ggtattattg agaaagaaaa agtattaaag agcagtagaa ataagaaaat
    56041 ggaggcagta tcttatgagt aaaaatgtat taatagtatc agctagtcct agaaaaggtg
    56101 gaaattctga tttattgtgt gaccagttta tacaaggggt attagaatct aaaaatcaag
    56161 tggagaagat atttttaaaa gataaagata ttaactattg tactggatgt ggtgcttgtt
    56221 atgaaaaaga agcaaattgt tcacagacag atgacatggg agaaattctt gaaaaaatga
    56281 ttggggcaga tgtgattgtt ttagcgactc cagtttattt ttatactatg aatgcgcaaa
    56341 tgaaaactat gattgataga acttgctcta gatatactga aatttgtgat aaagatttct
    56401 attttatcgt tacagcagca gatgaaaatg tggctgatat ggaaagaaca atagaaggat
    56461 ttagaggatt tacatcatgt ctaaatggtt ctaaggaaaa aggtatagta tatggtgtag
    56521 gtgcttggaa tgtaggtgat attaagggaa gtaaggcaat gaaacaggca tatgaaatgg
    56581 gtaagttggc gtagtatgtt tgtataaaat tgtataaaat tgaatatatt cttatcattt
    56641 caacaataaa aagaggctta tctgtatttt gagacagcct ctttgtgcta tatcatttat
    56701 ttttattcta tatccttatt atacccttta tttttttatg cctatttaag tatctgttgt
    56761 tactcatata ttttaataat tacccttaaa aaactataca gattcctgca taatattatt
    56821 ttctttagta attaattttt ctaggttttt ccaatccatt tcttccatat ttgcaaaata
    56881 atgaccactt cctatgcaag tcaggtaaga ctttccatct aattcaaacg aagaacctcc
    56941 aatacacttt gaattacatt tcttacaagt acgagtttta gttatactat ctttaatagt
    57001 tttagagcat tcctccacag catctttata tgtatttaga tgaaaaagat ttgctttaac
    57061 tctccatttt ttttcattac attcaatagt aaataagcta cgttttggtt tcttagttga
    57121 atatactatt ttgtaagaac gagcacctgt ttttggttca attttacaat ctaatgattt
    57181 accaagttca tgtaaatgac atgcaatatc ataatcttta ccacttagta cttctaacat
    57241 ttcttctgtt gtttctgctg ttaattcact tttgctcata ttaaaaaaat ccccctatat
    57301 aaataataat ttcatatgaa aataattaat ataagtatat taaataaaac tattaaaatc
    57361 aataaaatta ctgcaatctt acattattgg gcatagaatg agagctaatg atttattaga
    57421 aataagactt aatagtatga aaatttactt agacgtggta caattctata aaagatttaa
    57481 aactaggaaa ggagaaagtt gttgagatac ggccaatata acaatttatt tataagttgt
    57541 aaatttatta tgagattaat tagattgtta agtaatacta tcaaaaggta gttttttgga
    57601 ttttcagcaa cagtggtaga tattgataat tttttggtta ttattatatt tagctgttat
    57661 attttcaata ggctctatga taactagggt aaataaggta tgggtaaagg ttttattatt
    57721 tataatagtg ggattgtcaa ctatagttct ttcatatgta ataacttgat tatgcaaaat
    57781 tctatgaagc aggaaccctg tgactttagt catgggaggt tcagaattta aggttaaaaa
    57841 ataactttaa tctgtaaatt ctcaaaacaa gaattctcat gttggtaaat ttctagatat
    57901 gagaaaaaaa ttgacatcat aaaaaagtaa ttttagagcg tttttttacg aaaaaattca
    57961 gaagtaacta ttttgaatga cttcacaaaa ttttatatat aaataaagtt tggcacgtta
    58021 attgctttaa taaaagttaa caagacacaa ataaacataa tcatctaagt attgattatt
    58081 tgaagtttta gatttgaagt ttaatctaaa ggttcgtatt aatattggtg tttaggaaat
    58141 tttattttcc tgtaaatata acttaataat aggaggtgaa gtcatgtcaa aagtagtaat
    58201 agctacagag aaagctccag gagcaattgg accatattct caagcaattc aagttggaaa
    58261 catagtttct acatcaggtc aacttccaat agatatgaag actggcgagt tagtatctga
    58321 cccaaaagaa gcaacaaaag cttctttaga taatgtaaaa gcaatattag aacaagctgg
    58381 tacaagtatg gataaaatat ttaagactac agtattcgta aaagatttaa aggattttaa
    58441 tgatattaat gaagtatatg ctacatattt taaagaaaat ccaccagcaa ggtcatgtgt
    58501 acaagttgct caattaccaa aagatgcagt tttagaaatt gaagcaatgg cagtattata
    58561 agtattataa caataaaacc aataacaaaa ctaataaaaa ttaaaaacta ataaaaaaag
    58621 tctacaatta aaaaagttta tattaaaaaa gtctatataa aaatctatct aaatatttaa
    58681 ctattgagct tttctcatat aatgtatatt tttatgtcaa aaatatattt gttatatgag
    58741 gaaagctttt ttt
//
LOCUS       DAJMZY010000011        56135 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.011, whole genome shotgun sequence.
ACCESSION   DAJMZY010000011 DAJMZY010000000
VERSION     DAJMZY010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 56135)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56135)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56135
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.011"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            34..732
                     /locus_tag="OE968_000659"
     CDS             34..732
                     /locus_tag="OE968_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7217974.1"
                     /translation="MKISSQYRSQYSFRYESNINNTRINESMVKKNETVGKDTYLSNI
                     MKQKQELNDRIRDLKYRQEVYTKKINDAIKNLCKSEIRETTNNFSNIEIGIKNSIIEE
                     KNKSTMLDENSTYLNTNDEKESLITKESNEKIEEEILNDEKLEELEQKKDYKEDSNKK
                     EKVSEDLSLVGKTREELENMLKNFINLTQEEIMKLESRIEKLDKNAEEYKQNSKTNIF
                     DKTDEQKKHINVLI"
     gene            910..1800
                     /locus_tag="OE968_000660"
     CDS             910..1800
                     /locus_tag="OE968_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7217975.1"
                     /translation="MKKNILTTMITMIIILMMSMTVMAEPYQEDETSSLKKQSANERN
                     QTNIGTMDGRVQTNAISKGANYDPKYPLKGMLTQLGLNTTGKEGWDLLYGGNPNGVEL
                     RADGKYYYINKGMEGLGFYAAALSGGSYQRIGFGKLDPIEVIADGNWISYKQAQDTLT
                     VIRNFLNSFDWRNASEMERANRAAKLVTEAKYADSKYCNIVYGNLVDKRGVCGSFASS
                     FHLLTRLMGMDSLSILNPSLNHAWNYIQIDGKWYRFDGSEISAFGGSLDFDYRKLKDA
                     TREMTTYYDAKALSILGFNQ"
     gene            complement(2193..3149)
                     /locus_tag="OE968_000661"
     CDS             complement(2193..3149)
                     /locus_tag="OE968_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HCP7217976.1"
                     /translation="MENNTIQKQLRDLSKKIWHIYILNPEEENLKFIISLLDDNLALI
                     GTGKHEFYETLEEFIIGLEKDQTESEQIDFEIIDEWYSCTKVTDEAFIVYGTLWVIEK
                     DYLEKDIYVEMDTRFTMVYRVTDDMIKLIHVHHSIPNFDQMKDEYYPKTITEKAQEAL
                     AMANEFKLKSEKDLMTGLYNRHFFEVHIKEMLKTVSHGYFYIFDLDNFKQVNDIFGHV
                     RGDEILIHFSNILTKVFVNDAIIGRLGGDEFAVFEYSNQSKENVENKAKKVLELCLES
                     NSCSIGISKLENNSDTFQSLYKQSDYALYYSKRNNKGNFSWF"
     gene            3852..4847
                     /locus_tag="OE968_000662"
     CDS             3852..4847
                     /locus_tag="OE968_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCP7217977.1"
                     /translation="MSIIELNELTKSYRRFEKKAGFMGSVKSLFNRKYTEKTAISSFD
                     LKIEEGEFVGLIGQNGAGKTTLIKMLTGIIAPSSGEISVMGYYPNKLENNFKKQYAVV
                     MGQKSQLFFELTPADTFLLFKELYDISNEEYKKNLDYFIELFEVSDYLNVQVRTLSLG
                     ERMKMELIVALLHNPKILFLDEPTIGLDAIAQKQIRYFLKEVNETKGTTIILTSHYME
                     DIKSLCSRSIVVENSRKIYDGSTEKLFNYFQKYKKITVSFSNETNIVFPKDCKVVEQT
                     NHKISVIVPKERGNETIKWIFDKYDVKDVMIEEEDIGSIVERIYKKGSDEYYEQL"
     gene            4825..5688
                     /locus_tag="OE968_000663"
     CDS             4825..5688
                     /locus_tag="OE968_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HCP7217978.1"
                     /translation="MSIMSNYNEASSNDSMFYKFKQSIRRYYEVAKINFKVQLIWRFD
                     VVVNMVFTIVKILFAYILWKAIFGENKIVSGFTFNSMLSYYIISSFLAGIDMSKSTSE
                     EICNRVKLGTFSKYMIIPINVQNYFIAKNFGMTCFYFVFNMISAFVWIFIFKIDFAFT
                     SNPVQILISILMIFLGFIFMMKLHFFIGILSFKFLEISFLKMIIENIVEFITGTMIPL
                     VLLPETIVTVMKVFPFYYTTYLPSMLLIGRNSNEAIQGLIILALWVLFFSVVNKVMYK
                     RMRTLFDGVGI"
     gene            5685..6479
                     /locus_tag="OE968_000664"
     CDS             5685..6479
                     /locus_tag="OE968_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HCP7217979.1"
                     /translation="MMKKNLKIIFMLLKMKLSKMMVFRFDFFGAFFVDSSLFILQLLM
                     FNSIYSHVDSIGGWQQGEMLIFIGTFSLINAINMTIFFFGIYDIPRKIQEGELDYYIT
                     KPLDPLFRLTFENINIGSSPLILASILIVLYGISELNSEITLVMIIIYIFMVLLMTLL
                     FYDVCIILRTVSFFVISSSAIMRLEDNLLPMNMKIPGVIYEGIFKVLFYLILPYGIMS
                     TIPTQILAGTITINGLIYSILIVFLFTLFMWRFWKLGMRHYKSASS"
     gene            6764..8143
                     /locus_tag="OE968_000665"
     CDS             6764..8143
                     /locus_tag="OE968_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HCP7217980.1"
                     /translation="MSDVYYSENHEQDNLYEQDNLLAQRFNLFTLLKFAFPTIFMMIF
                     MGLYTIVDTIFVSRFINTNALSAINIVCPIINLIVGIGTMLATGGSAIVARKMGNGDI
                     EGANKAFSLIVLSGVVIGVIITGIGIVFMDYIIIWLGASEVLIKYCRSYLFIILVFAS
                     ANILQVLFQCLFVTAGKPQFGLWLVLGAGCANIILDYVFIVLLQMGISGAALATGVGY
                     LIPTISGMVFFSKNKGLLKFCIPRLDKRILFEACFNGSSEMVGQLSTAVTTFLFNAMM
                     MKLIGEDGVAAITIIIYSQFLLTSLYIGFSMGVAPIISYNYGSENNTQLNHVFKICIL
                     FISVASLLVFIFSISCSPIIVEIFSQRGSRVYEIARSGFYIFSFSFIFCGYNIFTSSM
                     FTALSNGKVSAILSFLRTFGFITIGLLILPNILNINGIWLAVPSAEILTLFLTVFCIF
                     KYKNRYKYM"
     gene            8591..9304
                     /locus_tag="OE968_000666"
     CDS             8591..9304
                     /locus_tag="OE968_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCP7217981.1"
                     /translation="MDTCFNKKILLVDDEKDIVDLIEEVLINDGFKNIIKAYNGLDAI
                     SLCKIACPDVVILDIMLPDIDGIEVCKKIREFSYCSILFLSSKNDDIDKILGLSSGGD
                     DYITKPFSPREIAFRVKAQLRRQQYQSIVPSDSEVIKIGDITIDIEGNRVYKDRNEIE
                     LTGREYHLLSYMAQNVNKIIGKERLYEQVWGVYSSICDNTIMVHIRHIREKIEDNPSN
                     PKILITVKGLGYKLVNRID"
     gene            complement(9576..11114)
                     /locus_tag="OE968_000667"
     CDS             complement(9576..11114)
                     /locus_tag="OE968_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HCP7217982.1"
                     /translation="MSLLKVTNLSQCFMDKSLYEKANFDLFKGEHIGVVGQNGTGKST
                     LIKILLGEVVPDSGEIKWQPNINIGHLDQYAEINRDTTISLYLHTAFEELYKIEKEMN
                     LLYQKSAISENEQYLIKASDYQEQLIASNFYSIDNEINKIANGLGLDSIGMNRVVREL
                     SGGQRAKVILAKLLLSNHDVLLLDEPTNFLDKEHVEWLSNYLNTFNGAFIVVSHDFDF
                     LEKISTGILDIEFGMIKKYHGKYSEFLKQKSHLREDYIRRYQAQQKKIEKEETFIRKN
                     KAGVNSKIARGRQKQLDKIERIAPPSFTGKPNIQFSEIEISAQNALTITNLEVGYYYS
                     LLPKLNFSVDGGQKIVITGFNGIGKSTLLKTLVKDIPRISGDFQFSEQVKIGYYEQDL
                     KWENPDKTPLQIVADKYPKLNTKEIRRHLARCGVKEEHVSRSVSTLSGGEQSKVKLCC
                     MMLSPCNFLILDEPTNHFDAETKDALQNALKQFRGSIILVSHEEKFYKGWIDKVFNIE
                     KQLV"
     gene            11996..12451
                     /locus_tag="OE968_000668"
     CDS             11996..12451
                     /locus_tag="OE968_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HCP7217983.1"
                     /translation="MDEIDLKIINSLKKNSRASTSEISRQINLSVPAVSERIRKIEQS
                     NLIQKYTIQINREKTKYKLLAFIFINTDLSKSMKEFKKTILEYDTVLECHHISGEYDY
                     LIKVLAEDTSNLEEFISVTLKEIGGIQKANTTIVLSTIKEEFNTIKDIF"
     gene            12500..13084
                     /locus_tag="OE968_000669"
     CDS             12500..13084
                     /locus_tag="OE968_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HCP7217984.1"
                     /translation="MKVLVFLAKGFETMEFSVFVDVMGWARNDYGHDIDVVTCGFKKQ
                     VMSTFNIQVLVDKTIEEVCVDDYDALAIPGGFEEFGFYDEAYDSSFLNLIREFNSKEK
                     IIASICVAALPVGKSGVLKNRKATTYHLKNGKRQRQLSEFDVNVVNEPIVVDKNIITS
                     YCPETAPHVAFKLLEMLTSKEQMDEVKLAMGFKL"
     gene            complement(13089..13412)
                     /locus_tag="OE968_000670"
     CDS             complement(13089..13412)
                     /locus_tag="OE968_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCP7217985.1"
                     /translation="MKKCLDNYSCPIEATLALIGGKYKTLILWHLKDTILRFNELKKL
                     IPKATPKMLTQQLRELESDGLIIRVVYPVVPPKVEYSLSDFGKSIIPILDSMCDWGSD
                     YLENL"
     gene            13564..14082
                     /locus_tag="OE968_000671"
     CDS             13564..14082
                     /locus_tag="OE968_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HCP7217986.1"
                     /translation="MNFVELAKKRYSCRNYQDRKVEKEKLEKVLDVARIAPTGGNRQP
                     QRLIVIQEKEGINKLSKAANIYDAPLAILVCGDKDKVWTRPFDGKQLTDIDTSIVTDH
                     MMLQATELGLASVWVCYFNPDIIREEFSLPDNLEPINILLMGYESKIPESPERHEKTR
                     VPLSEIVSYETL"
     gene            complement(14258..14926)
                     /locus_tag="OE968_000672"
     CDS             complement(14258..14926)
                     /locus_tag="OE968_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-binding protein"
                     /protein_id="HCP7217987.1"
                     /translation="MLEVSHKVKEIYPNIKFGVMVINITHSKPNKENFLVLKNSTIKN
                     IIEQHPEYNRKEKIKTEPVSSYIKYYKKFKKTYPVLLQLESILLKSKGIPDVGVTIES
                     MFLAELKNLLLTAGHDLDKMELPLKIELANGSEHFYGIGGKEHILTKDDLFLSDNIGI
                     LSSILNGPDNRTAITKDTKNIMYFVYGPDKISEKQIQDHLNDIKHYISSAFPDLKVNS
                     IDIF"
     gene            15041..16456
                     /locus_tag="OE968_000673"
     CDS             15041..16456
                     /locus_tag="OE968_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HCP7217988.1"
                     /translation="MWITINRNSNISLSRQIYCEIKDMILDGSLKFEQKLPSSRTLSK
                     ELSVSRNTVLDAYNQLIAEGYLETRNGYGTIVAKGISGHKVDFKLNDTFRDEKDLHTN
                     KQKNYIDFRSGVPELKLFPRKELSKLYKQILYDLSDSDFRYGSTAGVWVLRVEISKYL
                     FRTRGIRCNPKNIMIVSGSTQGLSLISQLLYKSNKKVAVEDPIHKGLLKVISSIGYSV
                     VGIKVDDKGMNTNLIKSIKGISFVYTTPSHQYPLGGILPIQRRLELIKCATENDYYII
                     EDDYDSEFRYEGQPISSLYELSPNKVIYIGSFSKILSPAIRVGFMLLPDNILESYKTL
                     KMYSDVHTETILQHVLAEFIGNGGLEKYIFRMKKLYNRKRKYLIKVLNTEFKNEFKIK
                     GEAAGLHIVAHFYNVKFTESLIHKIFEAGIKVYPIQQYAIENILEYDYEIILGYAHLS
                     FDEIEKGVKILSKIIHMNQGT"
     gene            16679..17137
                     /locus_tag="OE968_000674"
     CDS             16679..17137
                     /locus_tag="OE968_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCP7217989.1"
                     /translation="MEIIDYIEENLTENLNLDKIAYIANYSKYHLHRMFTNVVGCTIH
                     QYIQRRRLTEAARQLIFTDKYIIDIAITVGYSTHQSFTLAFRNLYKESPQVYRNKDEF
                     YPIQQRFVLNLNHQIQSEKCISYANMNYKQRRDEINSYLNFNINCEVKVA"
     gene            17134..17718
                     /gene="clpP"
                     /locus_tag="OE968_000675"
     CDS             17134..17718
                     /gene="clpP"
                     /locus_tag="OE968_000675"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HCP7217990.1"
                     /translation="MSLVPHVIEQTGQGERSYDIYSKLLKDRIIFIGEEINDAIASLV
                     VAQLLFLESEDPDSDIIIYINSPGGSATSGFAIYDTMNYVRCDVSTICIGMAASMSAF
                     LLAGGTHGKRCALPNSEIMIHQPMGGAKGQATDVKIAVDNILKIKERLDKILSENTGK
                     SIEDIRRDTDRDNFMTALEAKEYGLIDYIMNRNE"
     gene            18030..19106
                     /locus_tag="OE968_000676"
     CDS             18030..19106
                     /locus_tag="OE968_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HCP7217991.1"
                     /translation="MITISLCMIVKNEEEVIGRCLECVKDIVDEIIIVDTGSTDSTKE
                     IVSKYTDMVYDFEWIDDFSAARNFSFSKASKDYTMWLDADDIILEADREKLLKIKESL
                     DTSIDIVMAKYNVSFDENGNPTLSYYRERLFKRSSNHKWVDPIHEVVPLFGEVFYSDI
                     AISHKKLHRQDPLRNLRIFEKMISEGKTLEPRHQFYYSRELYYNARYKEAIEGFTKFL
                     DSSRGWIEDCISACRDLATCYYLINDEKSALYSLFRSFEFDEPRAEICCDIGKHMFDR
                     QKYKEAIFWYKVALTRDKNDTNGGFKSNDCYGYIPSIQLSVCYDRLGESDKAIYYHEK
                     TKEIKPNDSAVLHNENYFSKFKNS"
     gene            19173..21245
                     /gene="bclA3"
                     /locus_tag="OE968_000677"
     CDS             19173..21245
                     /gene="bclA3"
                     /locus_tag="OE968_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like exosporium glycoprotein BclA3"
                     /protein_id="HCP7217992.1"
                     /translation="MLLIMSRNKYFGPFDDNDYNNGYDKYDDCNNGRDDYNSCDCHHC
                     CPPSCVGPTGPMGPRGRTGPTGPTGPTGPGVGATGPTGPTGPTGPTGNTGNTGATGLR
                     GPTGATGATGPTGATGAIGFGVTGPTGPTGATGATGADGVTGPTGPTGATGADGITGP
                     TGATGATGFGVTGPTGPTGATGVGVTGATGLIGPTGATGTPGATGPTGAIGATGIGIT
                     GPTGATGATGADGATGVTGPTGPTGATGADGVTGPTGATGATGIGITGPTGPTGATGI
                     GITGATGLIGPTGATGTPGATGPTGATGPTGVGVTGATGATGATGADGATGVTGPTGA
                     TGATGANGLVGPTGATGAAGTPGATGPTGATGPTGVGITGATGATGATGPTGADGATG
                     PTGATGNTGADGVAGPTGATGATGNTGADGATGPTGATGATGADGATGPTGATGATGV
                     AGATGATGPTGATGATGADGATGPTGATGATGADGATGPTGATGATGVTGATGPTGPT
                     GATGATGATGASAIIPFASGIPLSLTTIAGGLVGTPGFVGFGSSAPGLSIVGGVIDLT
                     NAAGTLTNFAFSMPRDGTITSISAYFSTTAALSLVGSTITITATLYQSTAPNNSFTAV
                     PGATVTLAPPLTGILSVGSISSGIVTGLNIAATAQTRFLLVFTATASGLSLVNTVAGY
                     ASAGIAIN"
     gene            21414..22175
                     /locus_tag="OE968_000678"
     CDS             21414..22175
                     /locus_tag="OE968_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase"
                     /protein_id="HCP7217993.1"
                     /translation="MKNKIEISMNNFVKNYHKSNNITTKWQELLFAYASAEDDMFQKL
                     KSVVGTSHAMPKDFLENGKTIITYFIPFDESVNNSNIGGFECSEIWARAYIETNMLIS
                     NLNDFLCEELEKIGANSYAIPGSYNFDSEKLVSDWSQRHVAFIAGLGTFGLNNMLITE
                     KGCCGRIGSIITSLELEPTKRPENEYCLYKHNNSCKKCVNKCVKEALKEDGFNRNKCY
                     EMCMINEKKYTYIGGCDICGKCIVGVPCSVINPSR"
     gene            22484..22762
                     /locus_tag="OE968_000679"
     CDS             22484..22762
                     /locus_tag="OE968_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7217994.1"
                     /translation="MSYKKAIHILPEELLELIQEYVDGECIYIPRKSNNKKEWGSNTP
                     TREELSIRNMQIYEDYQVGYDLQYLSEKYYLSLKSIQRIVLQEKRKDI"
     gene            23055..23630
                     /locus_tag="OE968_000680"
     CDS             23055..23630
                     /locus_tag="OE968_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1062 domain-containing protein"
                     /protein_id="HCP7217995.1"
                     /translation="MKKITWEVEYISQLPVIRYCKKCGKKTEYICSGLFRVNAQHKYL
                     DIWLIYKCSNCDSTWNSTIYSRVNPKSLNPEILEQFHTNDYNLVKQYAMNMELLHRNG
                     AEVGIPEYKIVGQEININDLTQVHIISKYPCQLKVSTLLREKLGLSRKVFDEMLDCGI
                     IRSNSGVDLKKGKLNYEIMLDIGKEKQKSSN"
     gene            complement(23736..24569)
                     /locus_tag="OE968_000681"
     CDS             complement(23736..24569)
                     /locus_tag="OE968_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prenyltransferase"
                     /protein_id="HCP7217996.1"
                     /translation="MNVENQSLSDIEIILSHRYDNGADYWTTPDKRLIKGSPFSTLDS
                     VLYLLELGVNPDDTLLKECADLIFSTWREDGRFKLYPNGGIYPCHTANAANVLCHMGY
                     ASDIRMQKTFQHFLDTQYTDGGWRCNKFSFGRGPETEYSNPLPTLNILNAFRFSNYLN
                     KESKLDKAVDFLLDHWTIKKPIGPCHYGIGTLFMQVEYPFRNYNLFLYVYVLSFYNRA
                     KKDKRFLEALKILESKMIGNKIVVERVVPKLSKLSFCKKGESSEIATTHYYEILKNLE
                     K"
     gene            complement(24637..25266)
                     /locus_tag="OE968_000682"
     CDS             complement(24637..25266)
                     /locus_tag="OE968_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3786 domain-containing protein"
                     /protein_id="HCP7217997.1"
                     /translation="MDEKITKNNYNVPFDYVRKKLKELDPHTISNLSNIPFNNDLNRF
                     TLNFFDRQYIIDYPSGEVWNSNGSLCNNFELKILIVRYLINAKGIPRTNKYVTFKEIP
                     GGNVYYPNFLNRTLYRLSEVFTSQIDKYKLVMEKIGAEKVNMGDLAYRFTYMGNTSMV
                     FILWFGDDEFPPNSNILFDSNIVYYFNAEDLAVVPDTAINAILNKINQL"
     gene            25577..26236
                     /gene="cprR"
                     /locus_tag="OE968_000683"
     CDS             25577..26236
                     /gene="cprR"
                     /locus_tag="OE968_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CprR"
                     /protein_id="HCP7217998.1"
                     /translation="MSKILVVDDELDMLKLIENVLKRDGHEVKVISDVEKAMNMDFNY
                     FNLIILDVMMPKMDGFEVCKTIRNKVDCPILFLTAKNMESDIMYGLGIGADDYITKPF
                     GVGELRARITAHLRRESREKKNLLTISNVQFNFLGKEVSIDGKKINFTKSEYLICEFL
                     AKNKGQVFSKERIYESVYGFDGESDISTITEHIKNIRSKLKQYDIYTIETVWGIGYKW
                     V"
     gene            26447..27505
                     /locus_tag="OE968_000684"
     CDS             26447..27505
                     /locus_tag="OE968_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HCP7217999.1"
                     /translation="MDRLKNIRKSLLQYTFLFLLIGITIYLVFKTLDIKMLSNVMVMV
                     DKKFLFIGALAIMCHIMLEGVVMKIIIESTHKVNIRFIGFKLAIMGFYYNLITPFASG
                     SQPVQIYVLKKCKMPLSKASAVVTNKSIIFQIVVTFYCTILVLMNFAMLEKQMKMIMP
                     LVFLGIAINSFVLIMIILVILNPKKIKYFMRITIKHLSKIKFLKFLDNKIESIESFID
                     DYSKAINFFAKNKKVLISTIIVTFIQLSAYFSVSFWIYKAFNLQGYSYIYILTLQAFL
                     YMAISPIPTPGNVGANELAFFTIFKSVFPQPLMGYAVFLYGGFMYYLILIGSGIFTVI
                     THYRMKNRIGRNIVLSEN"
     gene            27756..29900
                     /locus_tag="OE968_000685"
     CDS             27756..29900
                     /locus_tag="OE968_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:28170..28172,aa:Sec)
                     /transl_table=11
                     /product="formate dehydrogenase H subunit alpha,
                     selenocysteine-containing"
                     /protein_id="HCP7218000.1"
                     /translation="MEKKILTVCPYCGAGCQLYLVVKDNKILRAEPANGRTNQESLCL
                     KGRYGWDFLNDPKILTPRLKKPMIRKQGVLEEVEWDEAINYTASRLNEIKEKYGPDSI
                     MGTGSARGPGNEANYIMQKFMRATIGTNNVDHCARVUHAPSVAGLAYSLGSGAMSNSI
                     PEIENADVLFIFGYNGADSHPIVANRIVKAKKNGAKLIVTDPRVTESARIADIHLPIK
                     GGTNMVLVNAFGNVLIEEGLYNKEFVQNHTQGFDEYKEIVKPYTAKYAEKITGIPEEL
                     IRKAMREYAKGKKAMILYGMGVCQFGQAVDVVKGLASIALLTGNFGRESVGIGPVRGQ
                     NNVQGACDMGALPNVYPGYQNVTDDKIREKFEKAWGVKLSPNNGYSLTQVPNLVLKEK
                     KLKAYYIFGEDPVQSDPDASEVREALDELEFVIVQDIFMNKTALHADVILPATSWGEH
                     EGVYTCADRGFQLMRKAIEPQGDVKPDWQIISEISTAMGYPMNYKNTKEIWDELRQLC
                     PSFLGATYEKIETQGCVQWPCKSESMEDKGTMYLYEGQKFSTPNGKGNLFAAEWRPPM
                     EVEDDEYPFSLCTVREVGHYSVRTMTGNCRTLSSLEDEPGRVQINSNDAEKLGIEDDE
                     LVRISSRRGSVITRATVTDRVKEGATYMTYQWWVGACNELTIANLDPISKTPEYKYCA
                     VKLEKLEDQELAEKCVREEYQSLKDKMTATNI"
     gene            29949..30782
                     /gene="fdhD"
                     /locus_tag="OE968_000686"
     CDS             29949..30782
                     /gene="fdhD"
                     /locus_tag="OE968_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase accessory
                     sulfurtransferase FdhD"
                     /protein_id="HCP7218001.1"
                     /translation="MNNIYSKTKLQENSKDKVFENSYSLVDYKYLNSFNVEVSKINEH
                     EVSIDNEEIIAEYPLSFILNDKYINTFLCTPYNLEELIVGFLKTKGYIENKKSLLKFE
                     INESERFAKVTIQEKQKNQDEQIIFLNSLDYITCAPVKSNIKINYDTIYSIMDRNLNS
                     SELFKNTGGVHSVSVFNFDKKIVTCEDVARHNAMDKAIGFCVLNDITLKDKIVAVSGR
                     ISLEMILKAAMTQIPIVVSKSAPTNLSIELSKKLNITLIGFVRGRRMNIYANPQRVIK
                     K"
     gene            30793..30966
                     /locus_tag="OE968_000687"
     CDS             30793..30966
                     /locus_tag="OE968_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218002.1"
                     /translation="MCTKKEEQRYSKCEICGVLIDDTDKVYNNTYNLCKKCKRNISTE
                     KIVKYINIYDESK"
     gene            31024..31575
                     /locus_tag="OE968_000688"
     CDS             31024..31575
                     /locus_tag="OE968_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HCP7218003.1"
                     /translation="MKNKIGSFVIADPNKCTGCRACEVACFTMHNQHNNVGYTVGTVD
                     IPVIPRLYLVKGDNFCMPIQCRQCEDAPCLNSCPQKAIVKENNIMSVNEEKCIGCKTC
                     LLACPFGAIDLLPQYEDGKEVEQVILDENKKIAYKCDLCKDNEKIACISACPQEALKL
                     VTPIDDKKAKNRQAALSLLLTNK"
     gene            31600..32976
                     /locus_tag="OE968_000689"
     CDS             31600..32976
                     /locus_tag="OE968_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron hydrogenase small subunit"
                     /protein_id="HCP7218004.1"
                     /translation="MIINIDKDLCTGCRECSKVCPVNAIEGEEGKPQEINLDRCVMCG
                     QCVQTCKSYASVIDEGFEFLQEKKQEREIPESINEPIFAAYNVCDIDKVKKALSDPNV
                     FTMVQCAPAVRVALGEDFGYYLGYLGAGKMAAALRALNFDRVYDTNFAADLTIMEEGS
                     ELIKRVTEGGTLPMFTSCCPAWVKFMEKNYPKLTNHLSSCKSPQQMGGAIFKTYGAEI
                     NNVDASKIFSVSIMPCTCKKYECDREEMDSSGYRDVDVVLTTRELAYLIKDMGIDFKN
                     LREEKFDSPLGSYSGAGTIFGVTGGVMEAAIRTGYELITGESIPDVEVKQVRGENGFR
                     KSTIKIGDLDLRVGVVSGLKNVIPVLEDLEKGKLDVDFIEVMTCPVGCVSGGGQPKIL
                     LEEYKELAYENRTKATYVHDEHLAIRKSHENPDIKKLYDEYLVEPLGEKSHHLLHTTY
                     CIGKEVAK"
     gene            32976..33491
                     /locus_tag="OE968_000690"
     CDS             32976..33491
                     /locus_tag="OE968_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HCP7218005.1"
                     /translation="MNYFVIADPDKCIGCRTCMIGCVVAHSDEDIFYQNLDEINFNPK
                     LSVIKTKEVSAPIQCRHCEDAPCAKACPNGGIVRVGNTIKINEENCIGCKTCMLACPI
                     GAIDIVTLKDVDEGKLCFRERMTANKCDFCIESPEGPACVNVCPTKAFTIVKDEDIDS
                     KVKNKRKLAIL"
     gene            complement(33569..34852)
                     /locus_tag="OE968_000691"
     CDS             complement(33569..34852)
                     /locus_tag="OE968_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugated bile salt MFS transporter"
                     /protein_id="HCP7218006.1"
                     /translation="MNTLLNNKFSIKNFSNAWVIVLGCMLIQAVPFSIVASIQPQFIS
                     YVVEGEGFSLASFSLIFTIGTIASAIASPFIGVLFSKVNIKILYLLGCIISSIAFATF
                     SICTELWQFYTVSCIVQIGATIISAIGIPVLISAWFDEESKGKALGFAFAGGSIGSIF
                     LQPLAVRLLATQGYSRSYLIFGIIALIVGIPVILFILRMPKDINEKVKSKGKKEKASD
                     TISPSVWGYTLKEAKKIKYFWIMTIGFIFVGIYVSSLSVQYPTYLRNYLNPILIGTVG
                     STFALFALIGNLFGGLLFDKFGQTKPLIISFVLVLIATLSLLLVDKSSTFAFVFAILK
                     GLSVFAYMIGPAYLTGSFFGQKEFGSIYGIVQLIFAVGFALGSTLFGLLVDNFGYRFS
                     WSIIILSVIIAYTLLIITSIGMKKLNKERLDKLMQ"
     gene            35040..35462
                     /locus_tag="OE968_000692"
     CDS             35040..35462
                     /locus_tag="OE968_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3783 domain-containing protein"
                     /protein_id="HCP7218007.1"
                     /translation="MSFEKINNNNLDKIHNRKCIMLVNFNKKELSLIKNVSNFAGIRD
                     HIILSDKNGENIIRDILDGNISNECENGIKSKSVIFNNTPSTQVNAFLEGLKKVRINR
                     PFTAMVTETSIDWTLNNLIENLVQERNAMSLGKTIEHK"
     gene            35564..36502
                     /locus_tag="OE968_000693"
     CDS             35564..36502
                     /locus_tag="OE968_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HCP7218008.1"
                     /translation="MKVLFTINYGKEKFDKIRELGYDVIHYSEDSIENNEDVNTADVL
                     VTYNPFERLDISKMKNLQYIQTTSVGIDQLPKEEVLKRNIKIANNRGGYSVPIGESIV
                     LYILEIYKNSAKFFKQQQNKEWKMDFSVSELYGQRVGFLGTGTISSEAAKRLKAFGVE
                     IWGVNTDGSSKKYFDKCFATEDMNIVFEECDIVVVAMPSTKSTDGIVNKDMFKLMKDG
                     SVFINVGRGNTVNQKDLEECVEKFRGVALDVFESEPLNKDNKLWECENVIVTPHNSWV
                     SDKNKERTFNMVYNNLKHYIMENKPVDNVVDISRGY"
     gene            36688..38712
                     /gene="ligA"
                     /locus_tag="OE968_000694"
     CDS             36688..38712
                     /gene="ligA"
                     /locus_tag="OE968_000694"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HCP7218009.1"
                     /translation="MSVKDEINKLIETINYHNERYYNQDSPEISDYEYDKLMKELISL
                     EEEHPELKRIDSPTNRVGGKPLDKFNQIVHKTPMLSLSNAFSEQDLRDFDKRVQEYVG
                     ENVEYVVEFKIDGLSVGLTYNNGEFEKGATRGDGVVGEDISQNLMTVKSIPLKINDKK
                     ELIVRGEVYISKDNFRKVNEQQEEQEQPLFANPRNLAAGSLRQLDPKLTAKRPLDIFV
                     FNMENIEEYDLESHSESLEYLEKLGFSVSQSYKVCKSIDEVIEHIEYWTDNRGNLDYE
                     IDGMVIKVNNIKQRDEMGYTAKSPRWAIAYKFPAEKKKTKIVDIIVEVGRTGTITPSA
                     ILEPVRLAGTTVSRATLHNEDYIREKDIKINDTVLVQKAGDIIPQVLEVIKEERTGDE
                     IDFKMPEKCPVCSEPTIRLEGEAAVKCINMSCPAQIRRGIIHFVSRDAMNIDGLGESI
                     ITLLLNEKIIQDVSDLYYIKKEDVVDLERMGEKSADNLINSIEKSKENDLWRLINGLG
                     IKFIGVKAAKILAYNFKDLDEVISATSEQLEELEEFGSIMANSVVEFFKEDKNMNVIN
                     KLKNVGVNTKSLDNTGEKVEKIFEGMKIVLTGTLPTLKRNDAKDMIEKRGGKATSSVS
                     KSTTFVLAGEEAGSKLTKANDLGIKVIDEERFLELLKLSSKDEVKAVLES"
     gene            38872..40221
                     /gene="rph"
                     /locus_tag="OE968_000695"
     CDS             38872..40221
                     /gene="rph"
                     /locus_tag="OE968_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HCP7218010.1"
                     /translation="MTRSYDRSNEQIRPVKITRDYTKYAEGSVLIEMGETKVICTASV
                     EEKVPPFLRNSGTGWINAEYSMLPRATQQRKIRDASRGKIDGRTQEIQRLIGRAIRSV
                     VDLNKLGERTIWVDCDVIQADGGTRTASITGAFVAVAEAIYKLYKAKIIKEMPITNFV
                     SAISVGIVNGIHMLDLCYEEDSKAQVDMNIIMTDKCEFVEVQGTGEEKPFSRADLNLL
                     LELGEKGNKELIRLQREALGEISDEILGMDYGNEVVIATNNAHKLEEIGEILKDFEYK
                     VYSLKDVDLAGIEIVEDGKTFEHNALIKARTIAKKTKLIAISDDSGLEVDALGKKPGV
                     YSARYAGEHATDEENRKKLLKAMQNIPMSKRNARFVSAIAVVFPDGKEFVVRGICEGM
                     IGFEEKGKNGFGYDSLFIVKGYDKTFGEIPSVIKNSISHRANALKLMKQEFIKRVVK"
     gene            40221..40691
                     /locus_tag="OE968_000696"
     CDS             40221..40691
                     /locus_tag="OE968_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HCP7218011.1"
                     /translation="MKIGIVSDTHMMIKNMEKTIPYLKECDLIIHAGDNFTDSRYIHS
                     MTNVGIIAVKGNCDFDAVEEEVVFEVANKTIFLCHGDKYGVKYGTHMLEKKATEVDAD
                     IVIFGHTHTPFREIKDGVLYINPGSTSLPRGVSYKSFVIMDIEEDDIKIEEIRI"
     gene            40885..42171
                     /locus_tag="OE968_000697"
     CDS             40885..42171
                     /locus_tag="OE968_000697"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HCP7218012.1"
                     /translation="MKAELIKKEGNKVTLKITVDNNKFEAAVNKAYNKSRNKYNIPGF
                     RKGKAPRIVIETQYGKGIFYNDAIEILFPEVYPEAIKELDIDPIDNPDLDIEEISKDN
                     GLVMVLNVEVKPEFELGNYKGIEIAKVENTVSDENVDAKLQEMVEKNARLVSVEDKAL
                     EDGDTAIIDFEGFENGVAFDGGKGENYNLVIGSNTFIPGFEEQLVGKKAGEEVEVNVT
                     FPEEYHSQDLAGKPVVFNVKINDVKVKELSALDDEFAKDTSEFDSLDELKADVRAKLE
                     EEAKNRADAETRNSVVEKVAENTEIEIPEVMIQHQIDNMLNELNYQLQYQGFGLQQLL
                     EMTGRTMEELREERKEDAKKLVKSSLVLEAITKAEGIEATEEEFKAELEKMASAYNME
                     VEKIEASLRDADKEDIKGQIKIRKTIDLLVDNATIA"
     gene            42321..42905
                     /gene="clpP"
                     /locus_tag="OE968_000698"
     CDS             42321..42905
                     /gene="clpP"
                     /locus_tag="OE968_000698"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HCP7218013.1"
                     /translation="MALVPVVVEQTGRGERSYDIFSRLLKDRIIFLGDQVNDATAGLI
                     VAQLLFLEAEDPDKDIHLYINSPGGSITSGMAIYDTMQYIKPDVSTICIGMAASMGAF
                     LLAAGAKGKRLALPNSEIMIHQPLGGAQGQATDIEIHAKRILKIKETLNEILSERTGQ
                     PLEKIKMDTERDNFMSALEAKEYGLIDEVFTKRP"
     gene            42924..44174
                     /gene="clpX"
                     /locus_tag="OE968_000699"
     CDS             42924..44174
                     /gene="clpX"
                     /locus_tag="OE968_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HCP7218014.1"
                     /translation="MSKYEEKRQLKCSFCGKNQDQVRRLIAGPNVYICDECVELCDEI
                     IQEEIEDTIDEDTTSLPKPKEMMEILNDYVIGQEKAKKALSVAVYNHYKRIYSKKSSS
                     KDIEIQKSNILLLGPTGSGKTLLAQTLARTLNVPFAMADATSLTEAGYVGEDVENILL
                     KLIQAADFDIEKAERGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKILEGTVAN
                     VPPQGGRKHPHQEFLKIDTTNVLFILGGAFDGLEKIIQKRGGDKTLGFGAKIESKKEL
                     DLGKLYEKVLPEDLLKYGIIPEFIGRIPVLATLELLDEDALMQILQEPKNALVKQYKK
                     LLELDDVELEFEEGALRAIAKKAIERNTGARGLRSIVESVMMETMFEVPSRDNIKKVI
                     VTEKSVNEDSVNPIIVLKDQEESA"
     gene            complement(44245..44772)
                     /locus_tag="OE968_000700"
     CDS             complement(44245..44772)
                     /locus_tag="OE968_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HCP7218015.1"
                     /translation="MSEIILLFLIFLKIGAFSFGGGYAMLPFIQQEFISKYHFITNQE
                     FLDLLAISQSTPGPVAINSATFVGFKTAGFFGSLAATIGVTIFALIGLTIISKLFSKF
                     KNNKKVENLLTVLRPITLGFILSAAFSSAKEVNWDLYGIIAFIASFYLLYKGKIGSIA
                     IVFVFGILGILLTFL"
     gene            complement(44760..45272)
                     /locus_tag="OE968_000701"
     CDS             complement(44760..45272)
                     /locus_tag="OE968_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HCP7218016.1"
                     /translation="MLKLFLTFLKIGAFTFGGGYAMVPLIQDELVNKQKLLEQEEFID
                     YLSIAQSYPGVLAVNISVLLGYKLYGIPGVLICTLGSALPSFCIVLVLSYLYFKNSSS
                     KILDGFFKGVAPVVIALILYSFTSMFKKLPKSKTNILLLIIAVLSVGVFNISPIYLII
                     GGGVYSLCQK"
     gene            45452..47815
                     /gene="lon"
                     /locus_tag="OE968_000702"
     CDS             45452..47815
                     /gene="lon"
                     /locus_tag="OE968_000702"
                     /EC_number="3.4.21.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase La"
                     /protein_id="HCP7218017.1"
                     /translation="MEQNYTKIDHELPLIPLRGLAIFPYMILNFDIGREISLKALDQA
                     MMDEELIFLTSQKEAEVDEPGEEDFYHVGTICKVKQMIKLPGDTVRVLVEGVSRGRVK
                     KIEQEDGYFRAVIEEIVFDSDNLDSETEVEIEAFVRNVFDAFEEYINIGNRVSPEILI
                     SLADIEDVDRFIDTIAANIYLKSSQKQEILEEFDIRKRLELIYSILLEEIDILKIEKK
                     ITLRVKKQMNKVQKEYYLREQLKAIQKELGEEEDINSEADEYREKLKKIKAPKTTKEK
                     IEKEIDKFSKISSMSPDVSVSRNYLDTIFSLPWNKETKDKLDITKAKDILDEDHYGLE
                     KVKERILEYLAIRTLAKSLKGPIICLVGPPGTGKTSIVKSIARALNRKFVRISLGGVR
                     DEAEIRGHRRTYVGSIPGRIINGVKEAQTKNPVFLFDEIDKMAADYKGDPASAMLEVL
                     DPEQNKDFVDHYLEIPFDLSKILFVTTANSLSNIPRPLLDRMEVIEVSGYIEEEKLNI
                     AKKYLLPKQIKEHALKENFIKIDDETLRSIINHYTREAGVRTLERTIGKICRKVAKKY
                     VEDPTLEEVVINKSDLETYLGKDMFKYQLAEVNPQIGLVNGLAWTEVGGVTLEVEVNV
                     LKGKGEIVLTGKLGDVMKESAKTGISYIRSIVDKFDIDPEFYKTNDIHIHIPEGAVPK
                     DGPSAGITMALAVISALTKRPVPGNIAMTGEITLRGRVLAVGGVKEKLLAAHRAGITK
                     VLIPKECEADLDEIPENVKEKMEFVLVEHMDEVLEQALLKSGENNEN"
     gene            47805..48416
                     /locus_tag="OE968_000703"
     CDS             47805..48416
                     /locus_tag="OE968_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HCP7218018.1"
                     /translation="MKIRSSEITMSAVNKSQYPAEGIPEIALAGRSNVGKSSIINTLL
                     NRRNFARTSQTPGKTRTINFYLINNEFYFVDLPGYGYAKIAKSEKEKWGGIMERYLES
                     RQELCSIFLLVDIRHEPTADDKLMYEWIKHFGYNCVVIATKADKISRGQYQKHISIIR
                     KKLQMESSEKVIPVSSLKKTGVEELWEEIVNQYNQHGYEITVD"
     gene            complement(48682..50052)
                     /locus_tag="OE968_000704"
     CDS             complement(48682..50052)
                     /locus_tag="OE968_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCP7218019.1"
                     /translation="MKQKWIVLIIICIGVFMSTLDGSILNIANPTIAADFKINMSQIQ
                     WVVTAYMLVVTATMLFFGKLGDKVGSNRLYTLGFFIFTIGSFLCSMSNNLSTLISSRI
                     FQAVGASILMATGLGIVSNAFPANEKGKAIGITGAVVGIGNMSGPVIGGIILEHFGWP
                     SIFIINIPIGIIAVFLGIKFLPKPVLDEQNKSFDIPGLLLFASCTTLILLAMNEKGNT
                     RLYLGITALIIFLLLALREVKFEQSFIDLPLFKNRNFTVGNIIGVACYFPQMAVSFLL
                     PFYLEQLKNLSPMMAGYVMTVHPLIMVLIAPIAGSLSDKHGAKNILTASFSFMTISLV
                     GMALLKADSPLYLLIVCLVIFGLGLGAFSSPNNSSILADVPPQKQGYGGSFLATIRNL
                     SFALGTAFFSSFFAQSLTYNQKFKSHTSAYVIASNQSYWIAASVCFVGLILTVFFMRK
                     TDKSIS"
     regulatory      complement(50227..50342)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            50630..51709
                     /locus_tag="OE968_000705"
     CDS             50630..51709
                     /locus_tag="OE968_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HCP7218020.1"
                     /translation="MEGKVKKAFPGGNTSQGSYSFFDYIIPENVKRVFCLKGGPGVGK
                     SSLMKKIYKEFLHRGYDIDLYHCPSDPSSLDGLVIKKLGVVLMDATAPHTMDPKLPGA
                     LDEIINLGDYWNTEELEKNKQEISVYDKDISNSFKRAFKFLKSAEPIFRDIEEKYSDC
                     MDYGKVNLVTEEFIKRLFDGVKSTGNLKREKHLFGSAITPVGCLDYTENILKDVKKVY
                     YLDGEIGTGKTTLLNKVYKKAIEKGLNVEVYHYPLIPEKIETVLLTDLDIGITISTTF
                     KEEDTIDLNQFLNREKLLKYEEDIKFDEKVLDDLICWAVLNLKRAKSKHDIIESYYSP
                     NMRFDEVGKLRDKLIKRILKYEENL"
     gene            52101..52781
                     /locus_tag="OE968_000706"
     CDS             52101..52781
                     /locus_tag="OE968_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF881 domain-containing protein"
                     /protein_id="HCP7218021.1"
                     /translation="MKKQYVFIILASTILGILVGTIFRDYSNEETVYTSKDKSIRKEI
                     KMTRKSIKELTKEKDKLDKEINSMKQNQKNSEEISEIETLRDSLSYSDVKGSGIILSI
                     DAIDEKTGNIANSIDYNKILVKVINELKVNGGKYIEINGQRINQYSEVVLAGSHININ
                     GVPVAQPYEIKCIGDKEKLSNYVDKGSKYLDSIQTNYPMKISIKTEENISMKKMNIPN
                     KLKYIKGD"
     gene            52774..54153
                     /locus_tag="OE968_000707"
     CDS             52774..54153
                     /locus_tag="OE968_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HCP7218022.1"
                     /translation="MIKIILEESSLPMLIPEKLAKKYNVFPVEFQDDNLVVEIEDEDI
                     YALQDLRLATGKEIILKKEKKELISEKIEKYYNSFELDEDYAKKLFENLLEKAIKENA
                     SDIHIEPFKEHLIVRMRVDGELKEVSKFLVDVYPSLSTVIKLKASMDITEKRLPQDGR
                     VDIKLGGNLIDIRVSSIPTVYGEKIVLRILNRDTFLKDKLELGFSEEAIKSINRIINK
                     RAGILLVTGPTGSGKTTTVYSLLNDLKGINKNIMTIENPVEYKMDGISQIQVNSKVGL
                     SFDVGLRAILRQDPDIIMVGEIRDAETAKIAVRAAITGHLVISTLHTNDAVSSIARLL
                     EMQIPPYLLNASLIGVISQKLVRKVCNHCSHEIMIKDNFSGDVNTKVAVGCEKCNDKG
                     YFGRTAIYEILEINDDIKTCIRNMEDSSTIKDVAQNNGMITFEDSCKRLINEKITTLE
                     ECLVVNEMI"
     gene            54324..55409
                     /locus_tag="OE968_000708"
     CDS             54324..55409
                     /locus_tag="OE968_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HCP7218023.1"
                     /translation="MRLSKNIFYNLEKFYLVLNRISDKEIRVICKEIGILLESGCEIT
                     KIFEIIESQSSKKAKNLLSIVSNHIQKGNSIAESFQITGIFSKFFISMIKAGETSGNL
                     DIIMSDLSNYYDKEYKLKMKIITISIYPIILIILSILSMLFIFVFVIPNFQVVFTNNG
                     IEPPLITRVLMGISTVVTNNLAYIIFSFILFSIGSIYFFITNDNIKKLINSLKFKIPF
                     IKKINQLVATTRFSRALSVLISSGIQIVEAIDMSASVIDNEFIYERLKISNNYIKKGN
                     SIGKSLNLANVFPKLFISMANTGEESGKLDKSLNVINKFYENELNNKIEQIMKFIEPM
                     LIVFMGLIIGTFILAMVVPMFDAITNF"
     gene            55463..55822
                     /locus_tag="OE968_000709"
     CDS             55463..55822
                     /locus_tag="OE968_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HCP7218024.1"
                     /translation="MINLINKKRKGFTLVEMIVVVTILGVISSIALVKYSKVQESAKL
                     NADYTNAANIVTAASMAINDDEKTIDSLSVETLKEKGYLNTVPVPQSTSGKFELVIND
                     SGTDISVNINSKQFYPK"
     gene            55875..>56135
                     /locus_tag="OE968_000710"
     CDS             55875..>56135
                     /locus_tag="OE968_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pilus assembly protein PilM"
                     /protein_id="HCP7218025.1"
                     /translation="MAIIKKILNLEINDDYIRLVFLRKSHKKVFIDKSIIKEINFDIK
                     NDSNSIEKIKYIEDVVRFVKEEIGKSKILYKNLYFNIQIQDIV"
BASE COUNT        22026 a         6412 c         9763 g        17934 t
ORIGIN      
        1 taaacataaa tttattttaa ggaggtgaaa taaatgaaaa tatctagtca atatagaagt
       61 caatattcat ttagatatga aagtaatata aataatacaa gaataaatga aagtatggtt
      121 aagaaaaatg aaactgtagg aaaagacact tatttatcta atattatgaa acaaaagcaa
      181 gaacttaatg atagaattag agatttaaaa tatagacaag aggtttatac taaaaaaata
      241 aatgacgcaa ttaagaactt atgtaaatca gaaataagag aaacaactaa taatttttct
      301 aatatagaaa taggtattaa aaatagcatt atagaagaga aaaataaaag tacaatgtta
      361 gatgaaaatt caacttatct aaatacaaat gatgaaaaag aatctttaat cactaaagag
      421 tctaatgaaa aaattgaaga agaaatatta aatgatgaaa aattagaaga gttagaacaa
      481 aaaaaggatt ataaagagga ttctaataaa aaagagaaag tatctgagga cttatcttta
      541 gtaggtaaaa ctcgtgaaga gcttgaaaat atgcttaaaa attttataaa tttaacacaa
      601 gaagaaataa tgaaacttga gtcgagaata gaaaagttag ataaaaatgc tgaagaatac
      661 aaacaaaatt caaagactaa tatatttgat aaaacagatg aacaaaaaaa acatataaat
      721 gtactgattt aaacaatatg ttttaaaaaa ataagtttat tatataatga aaatataaag
      781 gtacaatttc aatacacttc tattaaacca ataatttatg aatcagattt aatttcaatt
      841 tactaataac catatattta tgagttaata attttatgtt ttaaaaagaa ttaaataagg
      901 gggagtagta tgaagaagaa tatattaact actatgatta ccatgattat tatattgatg
      961 atgagtatga cagtaatggc agagccatat caagaagatg aaacatctag cttgaaaaaa
     1021 cagagtgcaa atgaacgtaa tcagactaat ataggcacaa tggatggcag agtgcaaaca
     1081 aatgcaataa gtaaaggtgc taattatgac cctaaatatc ctcttaaagg aatgttaaca
     1141 caacttggtc ttaatacaac aggtaaagag ggatgggatt tactctatgg aggaaatccc
     1201 aatggagttg agcttcgagc agatggtaaa tattattata taaataaggg tatggaaggg
     1261 ctaggatttt atgcggcagc attgtcaggt ggctcatatc agagaatagg ctttggaaaa
     1321 cttgacccta tagaagtaat agctgatgga aattggattt cttacaaaca agctcaagat
     1381 acacttacag taatcaggaa ttttttaaat agctttgact ggagaaatgc atctgagatg
     1441 gaaagagcta atagagctgc aaaattggta accgaagcaa aatatgcaga ctctaaatat
     1501 tgtaacatag tctatggtaa tctggttgat aaacgtggtg tatgtggaag ttttgcaagt
     1561 agctttcatt tattaacaag gttaatggga atggattcac tatctatatt aaatccatca
     1621 ttaaatcatg cttggaacta tatacaaatt gatgggaaat ggtataggtt tgatgggtct
     1681 gaaatatcag cttttggtgg atcattagac tttgattacc gtaaattaaa ggatgcaaca
     1741 agagagatga ctacttacta tgatgctaag gcattgtcta tattaggatt taatcaataa
     1801 aaataggggg aggcttctta tagagccttt ttttattgat ttgaaattta ataaggaatt
     1861 ttatatgaaa atttaatcaa taaaagcaaa aaaggctctt tataaagcct ttctaagtgt
     1921 ttttttaagt aaaatttttt atatcaacat cagttttaat caaaacatat aacattttgg
     1981 acttactttt aaaaataaaa ttattaaaat ataatattaa tcatgttttt agtttattat
     2041 attctataat agtggtcatg ttgactattg tagttttatt aagaatagtt ggtttatata
     2101 aatatatgca aagatagctt gttgtttact ttacttatta gtatatagga caagatactc
     2161 taataaattt gcctatttta atatcttttg tactaaaacc aactaaagtt tcctttatta
     2221 tttcgttttg aataatacaa agcataatcc gattgtttgt ataaagactg gaaagtatca
     2281 gagttatttt ctaatttaga tatacctata gaacaagaat tactctctag gcataattct
     2341 aaaaccttct ttgccttatt ttcaacattc tcttttgatt gattactata ttcaaaaaca
     2401 gcaaattcat ctccaccaag tcttccaata atagcatcat ttacgaatac tttagtcaaa
     2461 atatttgaaa aatgtattag tatttcatct cctcgaacat gaccaaagat atcatttacc
     2521 tgtttaaaat tatctaaatc aaagatgtaa aagtatccat gtgaaacagt tttaagcatt
     2581 tcttttatgt gtacttcaaa aaaatgtcta ttgtatagtc cagtcataag gtctttttct
     2641 gattttagtt taaattcatt tgccattgct agtgcttctt gtgctttttc agttattgtt
     2701 ttagggtaat actcatcttt catttggtca aagtttggaa tagaatggtg aacatggata
     2761 agtttaatca tatcatctgt aactctgtat accatagtaa atcgagtatc catttctaca
     2821 tagatatctt tttctaggta atctttttct attacccaaa gagtaccata tactataaaa
     2881 gcttcgtctg taactttggt acatgaatac cactcatcta taatctcaaa gtctatttgc
     2941 tctgattctg tttggtcttt ttcaagacct ataataaatt cttctaatgt ttcgtaaaat
     3001 tcatgttttc ctgttccaat taatgcaagg ttgtcatcta ataaggaaat aataaattta
     3061 aggttttctt cttctggatt taaaatataa atatgccaaa ttttttttga taaatctctt
     3121 aattgttttt gtattgtatt attttccata gattaccccc ttaagattta cagtttatat
     3181 tttaatgtat tataagttga actcttatta caatattatt ataatataga actaaagaaa
     3241 ttacatcctg tataagtaaa agtatatctt ttataataaa aatattacag taaaataacc
     3301 agttttaata tacgtattat atttttaatt tataaacgaa tattataaat gaaatttaaa
     3361 ttcaaccctg aagaaataag ctaaatgtat tagtatataa atccatactt gaacataaat
     3421 aacctttatg atatgatatc aataataata ttatgagagg agtgccttga tgtcggagtt
     3481 atataatggt aaccaacaat taaatagttg gagacacata tattctgtat aatcagaaat
     3541 ttcaagtgta tttttaatac atttaatttt tgtgtcttat tctgccttta tagataactg
     3601 acatatgaca acaaatagta tttaaaatat atattacttt gttaaattat ggtgtagtag
     3661 gctttaatct gctacacttt tattaatttt gtatagtatt attttgataa ctattttgaa
     3721 atagagagca ttaatttttc tagtccacag gagttttctg tttttgtgct gttaaatata
     3781 agcacagaga aaggcagata tatacctgtg gacttttttt atataaatta tgaaatatgg
     3841 aggtagttaa aatgagtata attgaactta atgaactgac taaatcttat agaagatttg
     3901 agaaaaaggc aggatttatg gggagtgtaa agtctttatt taataggaaa tatacagaaa
     3961 aaacagctat atcgtcattt gatttaaaga tagaagaagg agaatttgtt ggattaatag
     4021 gtcaaaatgg agctggcaaa actactctta ttaagatgtt aactggtatt attgcaccgt
     4081 cttctggaga aatatctgta atgggttatt accctaacaa attagaaaat aattttaaaa
     4141 aacaatatgc tgttgttatg ggccaaaaaa gtcaactatt ctttgaattg acaccagcag
     4201 atacgtttct tttatttaaa gaattatatg atatatctaa tgaagaatat aagaaaaact
     4261 tggattactt tatcgaatta tttgaggtat ctgactattt aaatgttcaa gttaggacgc
     4321 tttctttagg agaaagaatg aaaatggaac taatagtagc ccttctacat aatccaaaaa
     4381 tattattttt ggatgaacca actataggct tagatgctat agcccaaaaa caaattaggt
     4441 atttcctaaa agaagtaaat gaaacaaaag gaactactat tatacttact tctcattaca
     4501 tggaagatat taagagtctc tgtagtagaa gtattgttgt agaaaatagc cgtaaaatat
     4561 atgatggttc tacagagaaa ctatttaatt attttcaaaa atataaaaaa ataacagtta
     4621 gtttttccaa tgaaactaac attgtatttc caaaagattg taaagttgtt gaacaaacaa
     4681 atcataagat atcagtaatt gtgccaaaag aaagaggaaa tgaaacgatt aaatggattt
     4741 ttgataaata tgatgttaaa gatgtaatga ttgaagaaga agatataggt agtattgtag
     4801 agaggatata taagaaagga agtgatgagt attatgagca actataatga agcaagttca
     4861 aatgattcaa tgttttataa atttaaacag agtattagaa ggtattatga agtagccaaa
     4921 attaacttta aagtgcaact tatctggaga tttgatgtgg tggttaatat ggtgtttacg
     4981 attgtaaaaa ttttatttgc ttatatttta tggaaagcaa tttttggtga aaataaaata
     5041 gtctctggtt ttacatttaa ctctatgtta tcttactata taataagctc atttttagca
     5101 ggtattgata tgtcaaagag taccagtgaa gagatatgta atcgtgtaaa attgggcacc
     5161 ttttcaaagt acatgattat tccaattaat gttcaaaatt attttattgc taaaaatttt
     5221 ggaatgacat gtttttattt tgtatttaat atgatttctg catttgtatg gatttttata
     5281 tttaaaatag attttgcctt tacatcaaat ccagttcaaa tattaatttc aattttgatg
     5341 atttttctag ggtttatttt tatgatgaaa ctccacttct ttattgggat tttgtcattt
     5401 aaatttcttg agattagttt tttaaaaatg ataattgaaa atattgttga atttattaca
     5461 ggaacaatga taccacttgt actcttacca gaaactatag taacagttat gaaggtattt
     5521 ccattttatt atacaacata tttgccatct atgttactaa taggtagaaa cagcaatgag
     5581 gcaatacaag gattaattat tctagcatta tgggttttat ttttttctgt agtaaataaa
     5641 gttatgtata aaagaatgag aacattattt gatggggtgg gtatatgatg aaaaaaaatt
     5701 tgaaaataat atttatgtta ttaaaaatga aattatcaaa gatgatggta tttagattcg
     5761 atttttttgg agcatttttt gtagatagtt cattatttat attacaactt ctaatgttta
     5821 atagtatata ttctcatgta gactcaatag ggggatggca acaaggagag atgttaatat
     5881 ttataggaac tttctcatta ataaatgcga taaatatgac gattttcttt tttggtattt
     5941 atgatattcc acgaaaaatc caagaaggag aattagacta ctatattaca aaaccattag
     6001 acccactatt taggttaaca tttgaaaata ttaatattgg ttcatcacca ttaattctag
     6061 caagtatact tattgtttta tatggaatat ctgagttaaa ctcagagata actttagtta
     6121 tgataataat atatattttc atggtgttat tgatgacatt acttttttat gatgtatgta
     6181 tcatacttag aacagtttca ttttttgtta tatcatcttc tgcgataatg agattagaag
     6241 ataatttatt gccaatgaat atgaaaattc ctggtgtaat atatgaaggt atttttaaag
     6301 tattattcta tttaatctta ccatatggaa ttatgtcgac aattccgact caaattttgg
     6361 ctgggacaat aacaattaat ggattaatat actcaatttt aattgtattt ttgtttacat
     6421 tgtttatgtg gagattttgg aagttaggta tgagacatta taaaagtgca agtagttaat
     6481 aaattagtaa aaatagacaa tgtataacta tatataaata cgtttcatat gacactaaac
     6541 tatgtgaaca agtatttgcg ctaaaggcac tgaaagctat aaaatgatta aagtaaggat
     6601 ttaaaagttt ctttagtaga aatataattg tgtaaaaaag caagattaat taaaactata
     6661 tccaaataat tagatataat tcttatgcag aaaggaggtc tgtaaatgtc taattgtttg
     6721 gaatatattt taaaaataat taatgtacag aaaaataaac aaaatgagtg atgtatatta
     6781 ttcagaaaat catgaacaag ataatcttta tgagcaagat aatttactgg cacaaagatt
     6841 taatttattt actctattga agtttgcatt tcctactatt tttatgatga tttttatggg
     6901 gttgtataca atcgtagata ctatatttgt atcaagattt attaatacaa atgctctatc
     6961 agcaattaat attgtatgtc caattattaa tcttatagtt ggaattggaa ctatgcttgc
     7021 cactggagga agtgctattg tagcacgtaa gatgggaaat ggtgatattg agggagcaaa
     7081 taaagctttt tctttaatcg tattatcagg agttgtaatt ggggtaataa ttactggtat
     7141 aggtattgta tttatggatt atatcattat atggttagga gcaagtgaag ttttaattaa
     7201 atattgtcgt tcatatcttt ttattatctt ggtttttgct tctgcaaata tactacaagt
     7261 attatttcaa tgtttatttg taacagctgg aaagcctcaa tttggattat ggctagtgtt
     7321 aggtgctggg tgtgctaata taattcttga ctatgtgttc attgttctgt tacaaatggg
     7381 tattagtgga gcagcacttg caactggagt aggataccta attcctacca tttcaggtat
     7441 ggttttcttt tcaaaaaata aagggttact taaattttgt atacctagac tagataaaag
     7501 aatattattt gaagcttgtt ttaatggttc atctgaaatg gtgggtcaac tatcaacagc
     7561 agttactact tttttattta atgctatgat gatgaaatta attggtgaag atggggttgc
     7621 agctattaca ataattattt attctcaatt tcttttaact tcgctttata taggtttctc
     7681 aatgggtgtt gcaccaataa taagttataa ctatggaagt gaaaataata cgcagttaaa
     7741 tcatgttttt aagatttgta tattatttat ttcagtagca tctttattgg tatttatctt
     7801 ttctatatca tgttcaccaa tcattgtaga gattttttct caaagaggaa gccgagttta
     7861 tgaaattgca aggtccggat tttatatatt ttcttttagt tttatttttt gtggatataa
     7921 tatttttacc tcatctatgt ttacagcatt atcaaatgga aaggtgtctg caatattatc
     7981 ttttctacgt acatttggat ttataactat aggtttattg atattgccaa atatattaaa
     8041 tataaatggg atatggttag cagtaccaag tgctgagatt ttaaccttat ttttaactgt
     8101 tttttgtata tttaagtata agaatagata taaatatatg tagatattaa ataaatagct
     8161 tagatagata ttttatgttt taataagtaa ttcaattagt ggtagatata tactattgaa
     8221 aattaaagtt ataattgata taaagaatta ataaaaataa catataaaag tttaaaaggg
     8281 agttgaactt aaagtttgat tagaaaaagt caattttaag acaactcctt ttattttact
     8341 attgtattaa tctgtatctg taagtgtatt agtctaatat tataaacttt ggatgaaatt
     8401 aattttctat aggttttaat gtatcataca ctttatttta aagaaactta tcttaatttt
     8461 catagtgatt gaatttgtct attagagatg ttactattag taatgtaaaa gcaagagtag
     8521 tgaatataaa aaacaagata gtgatactgc aagattagaa tataataaat ttttatggag
     8581 agatttcaat atggatacat gttttaataa aaaaatatta cttgttgatg atgaaaagga
     8641 tatagtagat ttaattgaag aagtactcat aaatgatggt tttaaaaaca ttattaaagc
     8701 ttataatggt ctagatgcta tttcgctgtg taagatagca tgtccagatg ttgtcattct
     8761 tgatataatg ttaccagata tagatggtat agaagtgtgt aaaaaaattc gagagttttc
     8821 atactgttct attctttttt tatcatcaaa aaatgatgat attgacaaaa tactaggtct
     8881 tagtagtggg ggagatgact atataacaaa gccattcagt ccaagagaaa ttgcttttcg
     8941 agttaaagcg caattacgta gacaacagta tcaaagcatt gtaccatcag atagtgaagt
     9001 tattaaaata ggagatatta ctattgatat agaaggaaac cgtgtatata aagatagaaa
     9061 tgagattgag ttaactggaa gggagtatca tcttttaagc tacatggctc aaaatgtaaa
     9121 taaaattata ggaaaagaaa gactctatga acaagtatgg ggagtatata gtagtatttg
     9181 tgacaataca attatggtgc atatacgaca tataagagaa aaaattgaag ataacccctc
     9241 aaatcctaaa atacttataa cagttaaagg actaggatat aaacttgtga atagaatcga
     9301 ttagaataga ttttaatatt aatgaagata tctcaagttg aatttttagt taatgaggca
     9361 ttcttttatg ggtgaaatca aatgtatttt cgttatctca acaatgaaga agaggtctat
     9421 ctctattttg agatagcctc attaagttta tatcctggta atgtacttta tgttctaata
     9481 aaattttttt agtttatttg cagtgaaaca ttaactagaa cattaaaatt tgcattgaaa
     9541 taccaattaa ataatattgt atattgtgta taaacttata ctaattgttt ttctatatta
     9601 aatactttat caatccaacc tttataaaat ttttcttcat gggaaactag gattatactt
     9661 cctctaaact gtttcaaagc attttgtaaa gcatcctttg tctctgcatc aaagtgattg
     9721 gttggttcat ccagaataag aaaattacaa ggagataaca tcatacaaca taatttaacc
     9781 ttagattgtt caccaccact taaagtagat acactccttg aaacatgctc ttccttcaca
     9841 ccacatctgg ctagatgacg tctaatctct tttgtattta attttggata tttatctgct
     9901 actatttgaa gtggggtttt atcaggattt tcccatttta aatcttgctc ataataacca
     9961 attttaactt gttctgaaaa ctggaaatct ccagatatac gaggaatatc tttgactaat
    10021 gtctttaaca aggtagattt accgattcca ttaaaaccag ttataactat tttttgacct
    10081 ccatcaacag agaaatttaa ttttggaagt aaagaatagt agtatccaac ttcaagattt
    10141 gttatagtaa gagcattttg agccgatatt tcaatttctg aaaattgaat atttggtttt
    10201 cctgtaaaac taggaggagc tattctttct attttatcca attgtttttg tcttcctctt
    10261 gcaatttttg aatttactcc agctttattt ttacgtataa atgtttcttc tttttctatt
    10321 ttcttttgtt gtgcttgata ccttctaata taatcttctc ttaaatgtga tttttgttta
    10381 aggaactctg aatattttcc atgatatttc ttaatcatgc caaattctat atcaagaata
    10441 cctgtagaaa ttttttctaa aaagtcaaaa tcgtgggaaa ctacaataaa tgccccatta
    10501 aatgtattta aataatttga gagccattca acatgctctt tatctaaaaa gtttgttggt
    10561 tcgtctaata atagaacatc atggttagaa agtagtaatt ttgctaaaat tacctttgcc
    10621 ctttgaccac cactaagctc tctaacaaca cgattcattc ctattgaatc taatccaaga
    10681 ccatttgcta ttttatttat ttcattatct atagaataga aattacttgc tattagttgt
    10741 tcctgataat ctgatgcttt gattagatat tgctcatttt cagatatagc acttttttga
    10801 tagagtaaat tcatttcctt ttctatttta taaagttctt caaatgcagt gtgtaaatag
    10861 agtgatattg ttgtatctct attgatttct gcatattggt ctaaatggcc tatattgata
    10921 ttaggttgcc acttgatttc tcctgaatct ggaacaactt ctcccaataa aattttaatt
    10981 aatgtacttt tacctgtacc attttggcca actacaccta tatgttcacc tttgaataaa
    11041 tcaaagttag ctttctcata cagtgattta tccataaaac attgtgataa attagttact
    11101 tttaataaac tcataattca aactcctttt cttttattaa aaaatttatg gaaataaaaa
    11161 aagcagagga atggcattgt aaaatgccga cctctgcttt tggaaaaaca aaaggtcata
    11221 gacaagcatt gttgtctatg accagaaaat ctatattatc tatcggcaaa taggtaattt
    11281 taaataagca tagccaaaaa actatactaa acctatattt gccgatgaag atagaaagct
    11341 ttaagctttc agattaacct ctacacaacg cttcatcgta tacatttgtg tagagttaag
    11401 ttttctaaca agtttaacta attctatata aatcataatt attcacatcc taatcttagt
    11461 attaattcta gtttatctgt atttaaattg tacttttgta ctttgtggat tatcttattt
    11521 atttaaaata tgttttatta attatagctt aagttatgtt atcataatac ttagttatag
    11581 tcaataagaa agttatattt actattatta tattaattta gtaaatctat cattacaaag
    11641 ttatttgaag actcgctatc aataaaattt tatagtctat aagaaaatta agattatgag
    11701 ttttataatt ttgatatagg gatactattt tcataaatat tacaacatgt agaagtatat
    11761 gtctattatt gttgaatttt caatgatata ttaaggttct aatatattat acaaaataaa
    11821 aacattaatt caacttaaat aattttaagt attatatgtg ttttgattaa agaaaactaa
    11881 aattttaagg aaaaataaca tatttgtatt aaattttatt gaaatgatta aatttattta
    11941 cttaatgtaa attattagct aaaattgtat taaataatta aggaggtgag tagctctgga
    12001 tgaaatagat ttaaaaataa ttaattctct aaaaaagaat agtagggctt caacctctga
    12061 aataagcaga caaattaatt tatcagtacc agcagtctca gagcgtataa ggaaaattga
    12121 gcagtcaaat ttaattcaaa agtacactat tcaaattaat cgggaaaaaa caaaatataa
    12181 gcttttggct tttatattta tcaatactga tttatctaaa agtatgaaag aatttaagaa
    12241 aactatattg gaatatgata ctgtattaga atgtcatcat atttcaggag agtatgatta
    12301 cttaataaaa gtattagcag aagatacaag taatcttgaa gagtttatat cagtgacttt
    12361 gaaggaaatt ggggggattc aaaaagctaa tacaaccatt gttttatcta caattaaaga
    12421 agaatttaat acaataaaag atatttttta aataatttac tagtaaagtg ttaattatat
    12481 tttaggagga aaatagaata tgaaagtttt agttttttta gcaaaaggtt ttgaaactat
    12541 ggaatttagt gtatttgtag atgttatggg atgggctcgt aacgattatg ggcatgatat
    12601 tgatgtagtg acttgtggat ttaaaaaaca agttatgagc acatttaata tacaagtatt
    12661 agttgataag acgatagaag aagtatgtgt tgatgattat gatgctctag ctattcctgg
    12721 aggatttgaa gaatttggat tttatgatga agcatatgat tcatcttttt taaatctaat
    12781 aagggagttt aattcaaaag aaaaaataat cgcttctatt tgtgtggcag cattgccagt
    12841 tggaaaaagt ggtgttttaa aaaatcgtaa agctactaca tatcatttga aaaatggtaa
    12901 aagacaaaga cagttaagtg agtttgatgt aaatgtagtt aatgaaccaa ttgttgtaga
    12961 taaaaatatt ataacctcat attgtccaga aacagctcca catgtagctt ttaagctttt
    13021 agaaatgttg acatctaaag aacaaatgga tgaagttaaa ttagcaatgg gatttaaact
    13081 gtaatggttt atagattttc taagtaatca gaaccccagt cacacatgga atctaaaatt
    13141 ggaataatac tctttccaaa atcagatagc gagtattcta cttttggagg aacaacagga
    13201 taaaccactc ttataattaa accatctgat tctaattcac gtaattgttg agttaacatc
    13261 ttaggcgttg ctttaggaat taattttttt aattcattga acctcaatat agtgtcttta
    13321 agatgccaaa gtataagtgt cttatattta ccaccaatca atgcaagtgt tgcttctatt
    13381 gggcaactgt aattatctaa acattttttc atttttgggc tcctttattt attttaaagt
    13441 atctttttag gtactatatt acaaaaaagt gcattattgt aatatagtac catagtgata
    13501 aaattatagc ataggttaaa taaatcatca acttagccta ataaaacaat agggggtaaa
    13561 taaatgaatt tcgttgaact tgcaaaaaaa agatattctt gccgtaatta tcaagataga
    13621 aaggttgaaa aagaaaaact tgagaaggtt ttagatgttg caagaatagc tccaactggt
    13681 ggtaatcgtc aacctcaaag attgattgtt attcaggaaa aagaaggtat aaataaactt
    13741 tctaaggctg ccaatatata tgatgcgcca ttagcaattc ttgtatgtgg agataaagac
    13801 aaagtttgga caagaccttt tgatgggaaa caacttacag atattgacac aagtatagtt
    13861 acagaccata tgatgttaca ggcaactgaa cttggattgg caagtgtttg ggtgtgctat
    13921 tttaatccag atataattag agaagagttt agtttgccag ataatctaga accaataaat
    13981 atattattga tgggatatga atctaagata ccagagagcc cagagagaca tgaaaaaact
    14041 cgtgttcctt taagtgaaat tgtttcttat gaaactcttt aattataaaa ttaagttatt
    14101 cataggataa atgtaataaa gtgtttgtta taaacaaaat tcaaaataaa taatatctac
    14161 atataattaa ttttagtgaa gtatatctag tttaactaga atgtatactt cactaattta
    14221 tttattcaaa atatttatga ggattttaat atattaacta aaatatatca attgaattaa
    14281 cttttaaatc tggaaaagca cttgaaatat agtgttttat atcatttaaa tggtcttgaa
    14341 tttgcttttc tgatatttta tcaggtccat atacaaaata cataatattt ttagtatctt
    14401 ttgttatagc tgttcgatta tcagggccat taagaatact agataatata ccaatattat
    14461 ctgataaaaa taaatcatct tttgttaaaa tatgttcttt accacctata ccataaaaat
    14521 gttcacttcc atttgctaat tctattttca aaggtaattc cattttatca aggtcatgac
    14581 ctgctgttag aagaagattt ttcaattctg ctaaaaacat tgactcaatt gttacaccta
    14641 catctgggat accttttgat tttaatagaa tagattctaa ttgaagcaat acagggtaag
    14701 ttttcttgaa ttttttataa tactttatat aacttgaaac aggctctgtt ttaatttttt
    14761 ctttgcgatt gtattctggg tgttgttcta taatattttt aattgtagag tttttaagaa
    14821 ctaaaaaatt ttctttatta ggttttgaat gtgtaatatt tataaccata actccaaatt
    14881 taatattggg ataaatttct ttaactttat gtgatacctc taacataata tagactcctt
    14941 tttattttat attttatgat ataatcttag caaattaaaa gtggatttta tagttccatt
    15001 tttatagtaa ttttatagaa ccacttttgg aggtattaga atgtggatta cgattaatag
    15061 aaatagtaat atatcattat caagacaaat ttattgtgag ataaaagata tgattctgga
    15121 tggaagctta aagtttgagc aaaaactgcc atcatctagg actttatcaa aagaactatc
    15181 tgtatctcgt aatacagttt tagatgcata taatcaatta attgcagaag gatatttgga
    15241 aacaaggaat ggatatggaa caattgtagc taaaggaata tcagggcata aagttgattt
    15301 taagttaaat gatactttta gagatgaaaa agatttacat actaataaac aaaaaaatta
    15361 tatagatttt cgttcaggag ttccagaatt aaaactattt ccacgcaaag aactttcaaa
    15421 gctatataaa caaatactgt atgatttatc agattcggat ttcagatatg gaagtacagc
    15481 tggtgtatgg gttttaagag tggaaatatc taagtattta tttcgtacta gaggaattag
    15541 atgtaatccc aaaaacatta tgattgtttc tggttcaaca caaggtttat ctttaatttc
    15601 acagctttta tacaaaagta ataaaaaggt tgctgtagaa gaccctattc ataaaggctt
    15661 attaaaggtt atttcatcta ttggatattc agttgttgga attaaagtag atgataaggg
    15721 aatgaatacc aacttaataa aatcaataaa ggggatttct tttgtttata ctacaccttc
    15781 tcatcaatac ccattaggag ggattttacc tattcaaaga agactagagc ttattaaatg
    15841 tgcaacagag aatgattact atataattga agatgattat gatagtgaat ttagatatga
    15901 gggtcaacca attagttctc tttatgaact tagcccaaat aaagtaattt acataggttc
    15961 ttttagtaaa atattatctc cagctattcg tgttggattt atgttattac cagacaatat
    16021 tttagaaagc tataaaacct taaaaatgta ctctgatgtt catacagaaa caatattgca
    16081 acatgtatta gctgaattta ttggaaatgg aggtttagag aagtacatat ttagaatgaa
    16141 gaagttgtac aatagaaaac gtaagtacct cataaaagtt ttaaacacgg aatttaaaaa
    16201 tgaatttaaa ataaaaggtg aagcagcagg gcttcatata gttgctcatt tctataatgt
    16261 taaatttacg gaaagtttaa ttcataaaat ttttgaagca ggtataaaag tttatcctat
    16321 acaacaatat gcaattgaga atatattaga atatgactat gaaattatac taggttatgc
    16381 tcatcttagt tttgatgaaa ttgaaaaagg tgtaaaaata ctcagcaaaa taatacatat
    16441 gaatcaaggt acatagataa aacatgtagc aatctacata taatagatgt aattaagttt
    16501 aaactttaaa agaaatatat attaatattt ttgtataaaa atacctgata tttttttatc
    16561 gatactttat tgctatacac taaattaaga tagcaattta tattaagaaa aaactttttg
    16621 cataggttat aatacttaaa aggagaggat agagttgaaa acaaatacag atgttattat
    16681 ggagataatt gattatatag aagaaaatct tacagaaaat ctaaatttag ataaaatagc
    16741 ttatattgct aattattcaa aataccattt acacagaatg tttacaaatg ttgtaggatg
    16801 tactatccat caatacatac agaggaggag acttactgaa gcagctagac aacttatatt
    16861 tacagacaaa tatattatag acatagctat tacagtagga tattctacac atcaatcttt
    16921 tacactagca tttagaaatt tatataaaga atctccacaa gtatatagaa ataaagatga
    16981 attttatcct attcaacaga gatttgtttt aaatctaaat catcaaattc aaagtgaaaa
    17041 atgtatttct tatgcaaata tgaattataa acaaagaaga gatgaaatca attcttatct
    17101 taactttaat attaattgtg aggtgaaagt agcatgagtt tagtgccaca tgtaattgaa
    17161 caaacaggtc aaggggaaag gtcttatgat atatattcaa aattattaaa agatagaatt
    17221 atatttatag gagaagaaat taatgatgct attgcaagtt tagtagtagc tcaattactg
    17281 tttttagaat cagaagaccc agattcagat ataattatat atataaatag ccctggtggc
    17341 tctgctacat caggatttgc tatatatgat actatgaatt atgtcagatg tgatgtatcg
    17401 actatttgta ttggtatggc tgcaagcatg agtgcttttt tacttgcagg aggaacacat
    17461 ggaaaaagat gtgctttacc taattcagag attatgattc atcagccaat gggaggagct
    17521 aaaggtcaag caacagatgt aaaaatagct gtagataata tattgaaaat aaaagaacga
    17581 ttagataaaa ttctttctga aaatacaggt aaatcaatag aagatattag gagagataca
    17641 gatagagata attttatgac tgcactagag gctaaagagt acgggctgat tgattatata
    17701 atgaatagga atgaataaag tatcaaagta tcatattaaa atgtctgttt tacaaatata
    17761 tatataatat taaataagag tgtctcaaaa tgaacttttt agtttatggg acactctttt
    17821 ttgtatgaaa ttaaatatgg ttttatcatt tcaacaatta ttaccaaatt tcaagtttaa
    17881 taaattctac tataaaaaat acataaaaga taaggttctt tagtaacttt ctgtcgtcaa
    17941 aagtttttat aaatttaata acaaaacaag agaaaatacc atatattact tatgtctgca
    18001 atatatagaa gacaaaggag ttgtacatta tgattacaat aagtttgtgc atgattgtta
    18061 agaatgagga agaagttata ggcagatgct tagaatgtgt aaaggatata gtagacgaaa
    18121 ttataattgt agatacaggt tctacagatt ccacaaaaga aatagtctca aaatatacag
    18181 acatggtgta cgatttcgaa tggatagatg atttctctgc tgcaagaaat ttttcatttt
    18241 ctaaagcttc taaagactat actatgtggc ttgatgcaga tgacataatt ttagaagctg
    18301 atagagaaaa attattaaag attaaagaaa gcttggatac ttccattgat attgttatgg
    18361 caaaatacaa tgtatccttt gatgaaaatg gtaacccaac tctctcgtat tatagagaac
    18421 gattgtttaa aagaagttct aatcataaat gggttgaccc tattcatgaa gtagtacctc
    18481 tttttggaga ggtattttat tctgacattg caatatctca taaaaagctt catagacagg
    18541 accctctaag aaatcttaga atttttgaaa aaatgatttc agaaggaaaa acattggagc
    18601 caagacacca attctattat tctagagagt tgtactataa tgctaggtat aaagaagcaa
    18661 tagaaggttt tactaagttt ttagactcat caagaggatg gattgaggat tgtatcagtg
    18721 cttgcagaga tttagccaca tgttattact taattaatga tgaaaaaagt gccttatatt
    18781 cattgtttag aagtttcgaa tttgatgagc caagagcaga aatttgttgt gacataggaa
    18841 agcatatgtt tgatagacaa aaatataaag aagccatttt ttggtataag gtagcattaa
    18901 caagagataa gaatgatact aatggaggtt ttaagtcaaa tgattgttat ggatatatac
    18961 catctataca attaagtgtc tgttatgaca ggttaggaga atcagataaa gctatttatt
    19021 atcatgaaaa aacaaaagaa atcaaaccta acgatagtgc tgttttgcac aatgaaaatt
    19081 attttagtaa atttaaaaat agttgatagg tcacaatcat actaaatttg acatattata
    19141 tatagagctt aaaagctcaa atatatcagg aggtgctttt aataatgagt agaaataaat
    19201 attttggacc atttgatgat aatgattaca acaatggcta tgataaatat gatgattgta
    19261 acaatggtcg tgatgattat aatagctgtg attgccatca ttgctgtcca ccatcatgtg
    19321 taggtccaac aggcccaatg ggtccaagag gtagaaccgg cccaacaggt ccaacgggtc
    19381 caacaggtcc aggagtaggg gcaacaggcc caacaggacc aaccggtccg actggtccaa
    19441 caggaaatac agggaataca ggagcaacag gattaagagg tccaacagga gcaacagggg
    19501 caacaggccc aacaggagcg acaggagcta tagggtttgg agtaacaggt ccaacaggcc
    19561 caacaggagc gacaggagca acaggagcag atggagtaac aggtccaaca ggtccaacgg
    19621 gagcaacagg agcagatgga ataacaggtc caacaggagc aacaggggca acaggatttg
    19681 gagtaacagg tccaacaggc ccaacaggag caacaggagt aggagtaaca ggagcaacag
    19741 gattaatagg tccaacagga gcgacaggaa cacctggagc aacaggtcca acaggggcaa
    19801 taggagcaac aggaatagga ataacaggtc caacaggagc aacaggagca acaggggcag
    19861 atggagcaac aggagtaaca ggcccaacag gcccaacagg ggcaacagga gcagatggag
    19921 taacaggccc aacaggagca acaggagcaa caggaatagg aataacaggc ccaacaggtc
    19981 caacaggagc aacaggaata gggataacag gggcaacggg attaataggt ccaacagggg
    20041 caacaggaac acctggagca acaggtccaa caggagcaac aggcccaaca ggagtaggag
    20101 taacaggagc aacaggagca acaggggcaa caggagcaga cggagcaaca ggagtaacag
    20161 gtccaacagg agcaacaggg gcaacaggag caaatggatt agtaggccca acaggagcca
    20221 caggagcagc aggaacacct ggagcaacag gtccaacagg agcaacaggc ccaacaggag
    20281 taggaataac aggagcaaca ggggcaacag gagcgacagg tccaacagga gcagatggag
    20341 caacaggtcc aacaggagca acaggaaata caggagcaga tggagtagca ggtccaacag
    20401 gagcaacagg agcaacagga aatacaggag cagatggagc aacaggtcca acaggagcaa
    20461 caggggcaac aggagcagat ggagcaacag gtccaacagg agcaacagga gcaacaggag
    20521 tggcaggagc aacaggagca acaggtccaa caggagcaac aggagcaaca ggagcagatg
    20581 gagcaacagg tccaacagga gcaacaggag caacaggggc agatggagca acaggtccaa
    20641 caggagcaac aggggcaaca ggagttacag gagcaacagg cccaacaggc ccaacaggag
    20701 caacaggagc aacaggagca acaggtgcta gtgcaataat accttttgca tcaggtatac
    20761 cactatcact tacaactata gctggaggat tagtaggtac acctggattt gttggatttg
    20821 gtagttcggc tccaggatta agtatagttg gtggagtaat agaccttaca aacgcagcag
    20881 gaacattgac taactttgca ttttcaatgc caagagatgg aacaataaca tctatttcag
    20941 catacttcag tacaacagca gcactttcac ttgttggttc aacaattaca attacagcaa
    21001 cactttacca atctactgca ccaaataact catttacagc tgtaccagga gcgacagtta
    21061 cactagctcc accacttaca ggtatattat cagttggttc aatttctagt ggaattgtaa
    21121 caggattaaa tatagcagca acagcacaaa ctcgattctt actagtattt actgcaacag
    21181 cttcaggtct ttcattagtt aatactgtag caggatatgc aagtgcagga attgcaataa
    21241 attagattag ataagaaaag gcttctaata tcgtattgat attaggagct tttttaagaa
    21301 tgattgatga acatagtttt aatattaatt agtgcgcata ttataaaata ctattatata
    21361 atataaaata ataacattaa attggaaata tagaattatc taggggtgat actatgaaaa
    21421 ataagattga aatatcaatg aacaactttg taaaaaatta tcataaatca aataatataa
    21481 ctacaaagtg gcaagaactt ttgtttgctt atgcatctgc tgaagatgat atgtttcaga
    21541 agctaaaaag tgttgtagga acatctcatg ctatgccaaa agattttctg gaaaatggaa
    21601 aaactataat tacatatttt ataccttttg atgaaagtgt aaataatagt aatattggag
    21661 ggtttgaatg ttctgaaata tgggcaagag cgtacataga aactaatatg ttgatttcaa
    21721 atttaaatga tttcttatgt gaagaactag agaagatagg ggctaattca tatgctattc
    21781 ctgggtcgta taattttgac agtgaaaaat tggtaagtga ctggtcacaa agacatgtag
    21841 cattcatagc aggtcttgga acttttggtt taaataatat gcttattaca gaaaaagggt
    21901 gttgtggaag aataggaagc ataatcacaa gtttagaatt agagccaact aaaagaccag
    21961 aaaatgaata ctgcttgtat aaacataata atagttgcaa aaaatgtgtc aataaatgcg
    22021 tgaaagaagc tttaaaagaa gatggattta ataggaataa gtgttatgaa atgtgtatga
    22081 taaatgaaaa aaaatacact tatataggtg gatgtgatat ttgtggaaag tgtatagttg
    22141 gagttccttg ttcagtaata aacccatcaa gataatggat ttaagttgac taataatttt
    22201 aaagatagtt tataatgaaa aaattttagt tatcaaaata aatataatat aaaaactaaa
    22261 taaatgtgtt taaaaaatgg ataaataatt tgtgttgatt gacaaccagt tatactgttg
    22321 atagacttat atgtatcgct gtgatatata aggagggttg agattttatg tttgatttaa
    22381 tctttatttt tgcatagcaa gggctattgc aactatgaaa tttaatatat aaatagccct
    22441 ttgctattcc taatgaaaaa ttactattta ataggagagc aaaatgagct ataaaaaagc
    22501 aatacatata ttaccagaag aattacttga attaatacag gaatatgtag atggtgaatg
    22561 tatctatatt cctagaaaat ctaataataa aaaagaatgg ggaagtaata cacctactcg
    22621 tgaggagttg tcaattagaa atatgcagat ttacgaagac tatcaagttg gatatgattt
    22681 gcaatattta tcggaaaagt attatttatc tttgaaaagt atccaaagaa ttgtattaca
    22741 agaaaaaaga aaagatatct aaggatgagc cagtatagtt ttataattat actggctcat
    22801 tttcttttga taaaagtgtt tgaggtatag tttcttttaa gtggatgata taatttaagt
    22861 aatttcaata acttatacag tagctaacaa agctggttgt aaagtatcta ataagaagta
    22921 gtagcttttt atatgtttga aattaaaatt tattaaaatt aggaggtctt gttttgaaaa
    22981 aaatacttga ttatattcca ccttttcata actttctatt aatttagtaa tcttatagaa
    23041 aggaaattgc atttatgaaa aaaattactt gggaggtgga atatatctcc cagttacctg
    23101 taattaggta ttgtaaaaaa tgtggaaaaa agactgaata tatttgttca ggtttattta
    23161 gggttaatgc tcaacataaa tatttggata tatggttaat atacaagtgt tcaaattgtg
    23221 attcaacatg gaactcaact atatattctc gtgttaatcc aaaaagctta aatccagaaa
    23281 tactagaaca attccataca aatgattata atcttgttaa gcaatatgct atgaatatgg
    23341 aacttttaca tagaaatgga gcagaagttg gtattccaga gtataaaata gtaggacaag
    23401 aaattaatat taatgacctt acacaagttc atattattag taaatatcca tgtcagttaa
    23461 aggtatcaac attattacgt gagaaactag gtttatctag gaaggtattt gacgaaatgt
    23521 tggattgtgg gattattaga agtaactcag gagttgattt aaagaaaggt aaattaaatt
    23581 atgaaattat gttagatata ggcaaggaga agcaaaagtc ttcaaattga ttagaataac
    23641 taacttaata tattttcagg aacatcattt aaaaaaatag tgactttaaa aaatttaaag
    23701 ccactatttt ttaatatgtt ttatctatat aactattatt tttctaggtt ttttaatatt
    23761 tcgtaatagt gtgttgtggc tatttcactt gactcgcctt ttttacaaaa agataattta
    23821 gatagttttg gaactacacg ttcaacgaca attttattac ctatcatttt agattcaagt
    23881 atcttcaatg cttctaaaaa tctcttatcc ttttttgcac gattataaaa tgataaaacg
    23941 tagacataaa ggaataggtt ataattacgg aaaggatatt caacttgcat aaataatgtg
    24001 ccaattccat agtgacaagg gccgattggt tttttaatag tccaatggtc aagtagaaaa
    24061 tctacagctt tgtcaagttt tgattcttta tttagataat tactaaaacg gaatgcattt
    24121 aatatattaa gagttggtag tggatttgag tattcagttt ctggacctcg accaaaacta
    24181 aatttattgc aacgccaccc accatcagta tactgtgtat ctaaaaaatg ttgaaacgtt
    24241 ttttgcattc taatgtcaga tgcatatccc atatgacaga gtacgttagc agcatttgca
    24301 gtatgacaag ggtaaatacc tccatttgga tatagtttga aacgtccatc ttctcgccat
    24361 gtgctaaata tcaggtcagc acattcttta agtaaagtat catcagggtt cacacctaat
    24421 tctaatagat aaagtacact atcaagagta gagaaaggag aaccttttat taaacgctta
    24481 tcaggtgtag tccaatagtc tgcaccatta tcatacctgt gtgataatat tatttcaata
    24541 tctgataaag attgattttc tacattcatt ttttactcca tttcatatta tattctatta
    24601 aatctatcaa aaactttatt ataatattat ttatatttat aattgattta ttttatttaa
    24661 aattgcattt atagctgtat caggaacaac tgctaaatct tctgcattga agtaataaac
    24721 tatattagaa tcaaataata tatttgaatt tggaggaaat tcatcatctc caaaccaaag
    24781 tataaatacc atagatgtat tacccatata tgtaaaccta taagctaaat ctcccatgtt
    24841 tactttttca gctccaattt tctccataac taacttatat ttgtctattt gagatgtaaa
    24901 aacttctgaa agcctatata gagtcctgtt taaaaaattt ggataataaa cattgcctcc
    24961 tggtatttct ttaaaagtta catatttatt agttctagga atacctttag cattgattaa
    25021 atatctaact atcaagattt taagctcaaa gttattgcaa aggctaccat tactattcca
    25081 aacttctcca cttggatagt ctataatata ttgtctatca aaaaaattga gtgtgaatct
    25141 atttaaatca ttattgaaag gtatattact taaattacta attgtatgag ggtctaattc
    25201 tttgagtttt tttcgaacat agtcaaatgg aacattataa ttattttttg ttatcttttc
    25261 atccataatt ttttcctcca atttaaacaa ttaaaagtat atttataaaa agttttctta
    25321 ttattaattt tattatatat tcaaaatatt acaataataa attgttaaat aaatttttat
    25381 atttaagtaa atacgtgtaa aatgaatata aagtttttga aatataaagt ttttgtatct
    25441 aaaatatttt atttgtaaaa tagtaattaa ttattgtaag ctataatatg agagtattat
    25501 ggttaatgtg aattttaaag atattattaa atatataaat tagaatacta ttaaacggat
    25561 aaatggagga gttattatgt ctaagatatt agtagtagat gatgagttag atatgttaaa
    25621 gttgattgaa aatgtgttga aaagagatgg acatgaagta aaggtaatta gtgatgtaga
    25681 aaaagctatg aacatggatt ttaattattt taatctaata atattagatg ttatgatgcc
    25741 taagatggat ggttttgaag tatgtaaaac tataagaaat aaggttgatt gtccaatact
    25801 gtttttgaca gcaaaaaata tggaaagtga tattatgtac ggtcttggta taggtgcaga
    25861 tgactatata accaaacctt ttggtgtagg agaattaagg gctaggataa ctgctcattt
    25921 aaggcgagaa agtagagaaa aaaagaattt attaactatc tcaaatgttc aatttaactt
    25981 tttaggcaaa gaagtttcaa ttgatggtaa aaaaattaat tttactaaaa gtgaatatct
    26041 aatatgtgaa tttctagcaa aaaataaggg acaagtattt tcaaaagaaa gaatatatga
    26101 gtcggtatat ggttttgatg gagaaagtga tataagtact atcacagagc atataaaaaa
    26161 tatacgaagc aaattaaaac aatatgatat ttatacaata gaaactgtat gggggatagg
    26221 gtataaatgg gtgtaataag tataagtgtt gtttagtgaa aatattatat atatctacaa
    26281 aatgtttgta aaatattaat ctatatatta aaatttaatt tatagattaa tattttttgt
    26341 aaatgacaaa attgtaaggt attttgttat aaaatattaa gattcatagt gtatactaat
    26401 aatatagtat ttagtataaa tcttgagcaa aggatggtta tttctaatgg atagactaaa
    26461 gaatattaga aagagtttac tacagtatac atttttattt ttgttaatag gtataacaat
    26521 ttacctagtg tttaaaacat tggatattaa aatgctatca aatgttatgg ttatggtaga
    26581 taagaagttt ttattcatag gtgctttggc aataatgtgt cacataatgc ttgaaggagt
    26641 agtaatgaag ataattatag aaagcactca caaagttaat attagattta ttggttttaa
    26701 gctagccatt atgggatttt attataattt aataactcct tttgcttcag gaagccaacc
    26761 agtacagata tatgtactta aaaaatgtaa aatgccactt agtaaggcaa gtgcagttgt
    26821 taccaataag tctattatct tccaaatagt agttactttt tattgtacaa tacttgtttt
    26881 aatgaatttt gctatgttag aaaaacaaat gaaaatgatt atgcctctag tgtttctagg
    26941 gatagccatt aattcatttg tcttaattat gataatatta gttattttaa atcctaaaaa
    27001 aataaaatat tttatgagaa ttactataaa gcatttatca aaaattaagt ttttaaaatt
    27061 tttagataat aagattgaat ccatagaaag ttttatagat gattatagta aagcaataaa
    27121 tttttttgca aagaataaaa aggtattaat ttcaactata atagtaactt ttattcaatt
    27181 aagtgcttac tttagtgttt cattttggat atataaagca tttaatttac aaggttatag
    27241 ctatatttat atactgacat tacaagcatt tttatatatg gcaatatctc caataccaac
    27301 acctgggaat gtaggagcta atgaattagc ctttttcact atattcaaat cagtattccc
    27361 tcaacctttg atgggatatg cagtattttt atatggtgga tttatgtact atttgattct
    27421 gattggaagt ggaatattta ctgtaattac tcactataga atgaaaaata gaattggcag
    27481 aaatattgtt ttaagtgaaa actaaataag tttaaagaat atatattgag tatattaaaa
    27541 aatatgtcat aagaactaga atattttaat taaatggttg aaatataaag attattatga
    27601 catatttttt ttgaaattta agaggaattg tgagaaaatt gttgaattta atagatagta
    27661 ttgcaaaata tttatgattt tgcatattat aaaaacactc attatcttta agataaattt
    27721 tacttatcag gggataaatc taagggggga attgtatgga gaaaaaaatt ttaacagttt
    27781 gtccatactg tggagctgga tgccaattat atctagtagt aaaagataat aagatattaa
    27841 gagctgaacc ggctaatggt agaacaaatc aagaaagttt gtgtttaaaa ggtcgttatg
    27901 gatgggattt tctaaatgac cctaaaattc taacacctag gctaaaaaag ccaatgataa
    27961 gaaaacaagg tgtactagaa gaggttgaat gggatgaggc tataaactat acagcttcaa
    28021 gactaaatga aattaaagaa aaatatggtc ctgattctat tatgggaaca ggttctgcaa
    28081 gaggacctgg taatgaagca aactatataa tgcaaaaatt tatgagagct acaataggaa
    28141 ctaataatgt tgaccattgt gctcgtgtct gacatgcacc atctgtagcc ggtctggctt
    28201 actcattagg tagtggtgca atgtctaatt ctataccaga gatagaaaat gcagatgttt
    28261 tatttatatt tggatataat ggagcagatt cacatccaat agtggcaaat agaatagtaa
    28321 aagctaaaaa aaatggtgct aaattaattg ttactgaccc tagagtaact gaatctgcaa
    28381 gaattgctga tatacatcta cctataaaag gtggaacaaa catggtttta gtaaatgctt
    28441 ttggaaatgt attaatagaa gaaggtcttt acaataaaga atttgttcaa aatcatacac
    28501 aaggatttga tgagtataaa gaaattgtta aaccatatac agctaaatat gctgaaaaga
    28561 ttacaggaat cccagaagag cttataagaa aagctatgag agaatatgca aaaggtaaaa
    28621 aagctatgat actttatgga atgggtgtct gtcaatttgg tcaagctgtt gatgtagtta
    28681 agggacttgc atcaattgct ctacttacag gtaattttgg tagagaaagc gttggaatag
    28741 gacctgtacg tggacaaaat aatgttcaag gagcttgtga tatgggagct cttcctaatg
    28801 tatatcctgg ctatcaaaat gtaactgatg ataagataag agaaaagttt gaaaaagctt
    28861 ggggggtaaa attatctcct aataatggtt atagtttaac tcaagttcca aatttagtac
    28921 taaaagagaa aaagcttaaa gcttattata tatttggaga agacccagtg caaagtgacc
    28981 cagatgcatc agaagttaga gaagcattag atgaattgga atttgtcatt gttcaagata
    29041 tatttatgaa taagacagca cttcacgctg atgttatact tccagctact tcttggggag
    29101 aacatgaggg agtatataca tgtgcagata gaggattcca attgatgaga aaagctatag
    29161 agccacaagg agatgtaaaa ccagactggc aaattataag cgaaatttct acagcaatgg
    29221 gatatcctat gaattataaa aatactaagg aaatatggga cgaacttaga caattatgtc
    29281 caagtttctt aggtgctact tatgaaaaga tagaaactca aggatgcgtt caatggcctt
    29341 gtaagagtga aagtatggaa gataaaggaa ctatgtatct gtatgaaggt caaaagtttt
    29401 ctactcctaa tggtaaaggt aatttgttcg ctgctgaatg gagaccccct atggaagttg
    29461 aagatgatga atacccattt agtttatgta ctgtaagaga agttggacac tattcagtaa
    29521 gaacaatgac tggtaattgt agaacactta gttcattaga agatgaacca ggacgtgttc
    29581 aaataaattc taatgatgct gaaaaattag gaattgaaga tgatgaatta gttagaatta
    29641 gttcaagaag aggaagtgta ataacaagag caacagttac tgatagagtt aaggaaggtg
    29701 caacatatat gacttatcag tggtgggttg gagcttgcaa tgaacttaca atagcaaatt
    29761 tagatcctat atctaaaaca ccagagtata aatattgtgc tgttaaactt gaaaaacttg
    29821 aagaccaaga attagcagaa aaatgtgtaa gagaagagta tcaaagtttg aaagacaaaa
    29881 tgacagctac aaatatctaa tgatttatta gatttaagat ttataaaagg cagaaaggct
    29941 aatattttat gaacaatata tactcaaaaa ctaaattaca agaaaatagt aaggataaag
    30001 tttttgaaaa tagttatagt ctagtggact acaaatattt aaattctttt aatgtagaag
    30061 taagcaaaat aaatgaacat gaagtatcaa tagataatga agaaataatt gcagaatatc
    30121 cacttagttt tattttaaat gataaatata taaatacatt tttatgtacc ccatataatt
    30181 tagaggaact tatagtagga ttcttgaaaa caaaaggata catagaaaac aaaaaaagct
    30241 tattaaaatt tgagataaat gagagtgaac gttttgcaaa agtaactatt caagagaaac
    30301 aaaaaaatca agatgagcaa attatatttt taaattcact agactatata acatgtgctc
    30361 ctgtaaagag caatataaaa ataaattatg atacgattta cagtataatg gatagaaatt
    30421 taaattcatc agaattattt aaaaatactg gtggggtaca tagcgtatct gtatttaatt
    30481 ttgataaaaa aatagtcact tgtgaagatg tagcaaggca taatgcaatg gataaggcta
    30541 ttggattttg tgttttaaat gacataacat taaaagataa aattgtggct gtaagtggaa
    30601 gaatatcatt ggaaatgata ttaaaagcag ctatgactca aattcctatt gtagtatcaa
    30661 aatcagcacc gactaattta tcaatagagc tttctaaaaa attaaatata acgcttattg
    30721 gatttgtaag aggaagacgg atgaatattt atgcaaatcc acagagagtt atcaaaaagt
    30781 gagaatgaat atatgtgtac taaaaaagaa gagcaaagat attcaaagtg tgaaatctgt
    30841 ggagtattaa ttgatgatac tgataaggtg tataataaca catacaattt gtgcaaaaaa
    30901 tgtaaacgaa atataagtac tgagaaaata gtgaaatata taaatatata tgatgaaagt
    30961 aagtagacat atgatgaaaa taactagagg gttggaaata tacaaattga aaggtgggat
    31021 aatatgaaaa ataaaatagg ctcttttgta atagcagacc caaacaaatg tacaggttgt
    31081 agagcttgtg aagtagcttg ttttacaatg cataatcagc ataataatgt gggttataca
    31141 gttggaacag ttgatatacc tgttatacct agactttact tagtaaaagg tgacaatttc
    31201 tgtatgccaa tacagtgtag acagtgtgaa gatgctcctt gtttaaactc atgtccacaa
    31261 aaagctatag ttaaagaaaa caatattatg tctgtaaatg aagaaaagtg tataggatgt
    31321 aaaacttgtc tgctagcatg tccttttgga gctatagact tacttccaca atatgaagat
    31381 ggtaaagaag tagaacaagt aattttagat gaaaataaga agatagctta taaatgtgac
    31441 ttatgtaaag acaatgaaaa aatagcttgt ataagtgcat gtcctcagga agcattaaaa
    31501 cttgttactc caatagatga caaaaaagct aagaatagac aagctgcact tagtttattg
    31561 ttaacaaata aataaaggat acaggggtag gtgacgttta tgataataaa tatagataag
    31621 gatttatgta ctggatgtag agaatgttca aaggtctgtc cagtaaatgc tattgaaggt
    31681 gaagagggaa agccacaaga gataaattta gatagatgtg ttatgtgcgg tcaatgtgtt
    31741 caaacttgta aatcttatgc ttcagttata gatgaaggat ttgagttttt acaagagaaa
    31801 aaacaagaaa gagagatacc agagtctata aatgaaccta tatttgcagc atacaatgta
    31861 tgtgatatag ataaggtgaa gaaagcttta agtgacccaa atgtattcac tatggtccaa
    31921 tgtgcaccag cagttagagt tgctttagga gaagatttcg gatattattt aggatactta
    31981 ggtgctggga aaatggcagc agcacttaga gctttaaatt ttgatagagt ctacgatact
    32041 aattttgcag cagatttaac tataatggaa gaaggtagtg aattaattaa aagagtgaca
    32101 gaaggtggaa ctcttccaat gtttacatct tgttgtccag cttgggtaaa attcatggaa
    32161 aaaaattatc ctaaattaac taatcattta tcttcttgta aatcacctca gcagatgggt
    32221 ggtgcaatat ttaaaactta tggtgcagag ataaataatg tagatgcatc aaagatattt
    32281 agtgtttcta taatgccatg tacatgtaaa aaatatgaat gtgatagaga agaaatggat
    32341 tctagtggat atagagatgt agatgtagta ttaactacta gagaactagc ttatttaata
    32401 aaagacatgg gaattgattt taaaaattta agagaagaaa aatttgatag tcctttaggt
    32461 agttatagtg gagctggaac tatctttggt gttactggtg gggttatgga agctgctata
    32521 agaacaggat atgagcttat aactggagaa agtattcctg atgtagaagt aaaacaagta
    32581 agaggagaaa atggttttag aaagtcaact attaaaatag gagacttaga cttaagagtt
    32641 ggagtagtaa gtggattaaa aaatgtaata ccagtgcttg aagacttgga aaaaggaaaa
    32701 ttagatgtag attttattga agttatgact tgtcctgttg ggtgtgtaag tggtggaggt
    32761 caaccaaaaa ttttactaga agaatataag gaattggctt atgaaaatag aacaaaagca
    32821 acatacgtgc atgatgaaca tttagcaatt agaaaatctc atgagaatcc tgatattaaa
    32881 aaactgtatg atgaatatct ggtagaacca ttaggagaaa aatctcatca tctattacac
    32941 actacatatt gtataggaaa ggaagtggct aagtgatgaa ctattttgtt atagcagacc
    33001 ctgataaatg cataggatgt agaacttgta tgataggatg tgtagttgca cattcagatg
    33061 aagatatttt ttaccaaaat ctagatgaaa taaattttaa tccaaaactt tctgtcataa
    33121 agacaaaaga agtaagtgct ccaatacagt gtagacattg tgaagatgct ccttgtgcaa
    33181 aggcatgtcc aaatggtggt atagttaggg ttgggaacac aataaaaata aatgaagaaa
    33241 attgtatagg atgtaagact tgtatgttag catgtcctat aggtgcaata gacatagtta
    33301 cattaaaaga tgtagatgaa ggaaagcttt gctttagaga aagaatgaca gcaaataagt
    33361 gtgatttttg tatagaatcg ccagaagggc ctgcatgtgt aaatgtttgt ccaactaagg
    33421 catttactat agttaaggat gaggatatag atagtaaagt taaaaataag agaaaattag
    33481 ctatattgta atataaaaaa gatggagttt tatttatgat taaaagctcc atctttttta
    33541 ttataatatt tatatatcta aaaatcaatt attgcattag tttatctaat ctttctttat
    33601 tcaatttttt cattcctata gaagttataa taagtaaagt ataggcaatt ataactgata
    33661 aaattataat agaccaagaa aatctgtatc caaaattatc aactaacaat ccaaataatg
    33721 ttgaacctaa tgcaaatccc actgcaaaaa ttaattgtac gattccatat atgctaccaa
    33781 actccttttg accaaagaaa gagccagtta aataagcagg accaatcata taagcaaata
    33841 cagaaagacc tttcaaaatg gcaaatacaa atgcaaaagt agaagattta tctaccaata
    33901 gtaatgataa agttgctata agaaccaata caaaagatat aataagtggc tttgtttgac
    33961 cgaatttatc aaacaataat cctccaaata aattaccaat gagagcaaat aaagcaaatg
    34021 tggagcctac tgttcctatt agaataggat ttagataatt tctaagataa gttggatatt
    34081 gtacggataa tgatgaaaca tatataccaa caaatataaa tccaatagtc ataatccaaa
    34141 aatatttaat ttttttagct tcttttaatg tataacccca tactgaagga gaaattgtat
    34201 cagatgcttt ctctttttta cctttagatt ttaccttttc attaatatct ttaggcatcc
    34261 tgagtatgaa taatattaca ggtataccaa ctattaatgc tataattcca aatattagat
    34321 aagaacgact gtatccttga gttgctaata agcgaactgc aagtggttgt agaaatatac
    34381 taccaataga accaccagca aaagcaaagc ccaaagcttt tcctttgctt tcttcatcaa
    34441 accaagcact tattaaaaca ggtattccta tagcagatat aattgtagcg ccaatttgaa
    34501 caatacatga tacagtgtaa aattgccata gttcagtaca tatagaaaaa gtagcaaaag
    34561 caatactaga aattatacaa cctaataaat atagtatctt aatattgact ttagaaaata
    34621 atacacctat aaaaggtgat gcaattgctg aggcaatagt accaatagtg aatattagag
    34681 aaaaagaagc taaactaaag ccttctcctt ctacaacata acttataaat tgaggctgta
    34741 tacttgctac aatactaaat ggaacagctt gtatcaacat acaaccaagt actataaccc
    34801 aagcatttga aaagttttta atgctaaatt tattgtttag taatgtattc atggtatctc
    34861 tcctttaggt tatgatttgt agatattaat ctaattattc taattttata tattagtttt
    34921 ggatagccca actatttaaa tataatttgg gtattaatat aaaaattaac tataaaaatt
    34981 gattatttta aatgtatggg gtaaattaaa gtatataaat aaatgaaagg atggataaaa
    35041 tgtcatttga aaaaataaat aataataacc tagataaaat acacaacagg aagtgtatta
    35101 tgcttgtaaa ctttaataaa aaagaattat cattaattaa aaacgtaagt aactttgctg
    35161 gaataagaga ccatatcatc ttaagtgata aaaatggaga gaatataata agagacattt
    35221 tagatggaaa tatatcaaat gaatgtgaaa atgggattaa gagtaagtct gtaatattta
    35281 ataacactcc aagcacacaa gtaaatgcat ttttagaagg gctaaaaaaa gtgagaataa
    35341 atagaccttt tacagctatg gtaacagaga catctattga ttggacattg aataatttaa
    35401 tagaaaattt agttcaagaa cgtaatgcta tgtctttagg aaaaacaatt gaacataagt
    35461 aaatttaaga tatcttatag taattttaac taatgtacat tgagtatcat attatatttt
    35521 agaatataaa attttaaatg tgggtagatg gaggagattt gagatgaaag ttttatttac
    35581 aataaattat ggaaaagaaa aatttgataa aataagagaa ttaggctatg atgtcataca
    35641 ttactctgaa gatagtattg aaaataatga ggatgtaaat acagcagatg tactagttac
    35701 atacaatcca tttgagagat tagatatttc taagatgaaa aatttacaat atatacagac
    35761 aactagtgta ggtatagacc aacttccaaa agaagaggta ttgaagagaa atattaagat
    35821 agctaataat agaggcggat atagtgtacc tattggtgaa agtattgtat tgtatatttt
    35881 agaaatatat aaaaatagtg caaaattttt taaacaacaa caaaataaag aatggaagat
    35941 ggatttttct gtatcagaat tgtatggaca aagagttgga tttttaggaa caggtactat
    36001 atcttcagaa gcagcaaaaa gattaaaagc ttttggtgta gaaatatggg gtgtcaatac
    36061 tgatggaagt agtaaaaaat actttgataa gtgttttgct actgaagata tgaatattgt
    36121 atttgaagaa tgtgatatag tagttgtagc aatgccttct acaaaaagta cagatggaat
    36181 agtaaacaaa gatatgttta aacttatgaa agatggttct gtatttataa atgtaggtag
    36241 aggaaataca gttaatcaga aagatttaga agaatgtgta gagaaattta gaggggtagc
    36301 attagacgta tttgaaagtg aacctttaaa caaggacaat aagttgtggg agtgcgaaaa
    36361 tgtcatagta actcctcata attcttgggt gtcagataaa aacaaagaga gaacatttaa
    36421 tatggtttat aataatttga aacactatat aatggagaat aaacctgtag ataatgttgt
    36481 agacatatca agaggctatt aaaaataaaa aattttgata aaaataaaaa ctcttattag
    36541 tcgtattaaa gatactaata agagtttttt ttgtaataaa tttaaagccc aaaaagtgat
    36601 atactaaaaa atatataaat aggagataat taattatagg gaaatttcaa aataatttaa
    36661 ttttaaaaat atgaagaggt gcaaaaagtg agcgtaaaag atgaaattaa taaacttata
    36721 gagacaataa actaccataa tgaaaggtat tataatcaag atagcccaga aatatcagat
    36781 tatgaatacg ataagttaat gaaggagtta atttctttag aagaagaaca tccagaacta
    36841 aagagaattg attctccaac aaatagggta ggaggtaagc cattagataa gttcaatcaa
    36901 attgtacata aaactcctat gttgagttta tcaaatgctt tttcagagca agatttgaga
    36961 gattttgata agagagttca agaatatgtg ggagaaaatg ttgaatatgt tgttgaattt
    37021 aaaatagatg gtctttctgt aggtctaact tataacaatg gagagtttga aaaaggagca
    37081 actagaggag atggagttgt aggagaagat atttctcaaa acttaatgac agtaaaaagc
    37141 atacctctta agataaatga taaaaaagaa ctaatagtta gaggagaagt atatatatca
    37201 aaagataatt ttagaaaagt aaatgaacaa caagaagaac aagaacagcc attatttgct
    37261 aatccaagga atcttgcagc tggttcattg agacaattag acccaaaact aacagcaaag
    37321 agaccattag atatatttgt atttaatatg gaaaatatag aagaatacga tttagaaagt
    37381 cacagtgaat cactagagta cttagaaaaa ctaggatttt cagtaagtca gagttataaa
    37441 gtttgtaaaa gtatagatga agttattgag catattgaat actggacaga taacaggggt
    37501 aatttagact acgaaataga tggtatggta ataaaagtaa acaatataaa acaaagagac
    37561 gaaatgggat atacagccaa aagtcctaga tgggcaattg catataaatt cccagcagaa
    37621 aagaagaaaa ctaaaatagt agatataata gtagaagttg ggagaactgg tacaataaca
    37681 ccttcagcaa ttcttgaacc agtcagactt gcaggtacta ctgtaagtag agctacactt
    37741 cacaatgaag attatataag agaaaaagat ataaaaataa atgatacagt attagttcaa
    37801 aaagcagggg acataatacc tcaagtttta gaagttataa aagaagaacg tactggagat
    37861 gaaatagatt ttaaaatgcc agaaaagtgt ccagtttgtt cagagccaac aataagatta
    37921 gaaggagaag ctgctgtaaa atgtatcaat atgtcttgcc cagcccaaat aagaagggga
    37981 attatacact ttgtgtcaag ggatgcaatg aatatagatg gattgggaga atctataatt
    38041 acactgctat taaatgaaaa aattattcaa gatgtatctg atttatatta tataaaaaag
    38101 gaagatgtag tcgacctaga gagaatgggc gaaaaatctg ctgacaattt aataaattca
    38161 attgaaaaat caaaagaaaa tgatttatgg agacttataa atggattagg tattaaattt
    38221 ataggagtta aagcagctaa gatacttgca tataacttta aggatttaga tgaagtaatt
    38281 tctgcaacta gtgagcaact agaagaatta gaggaatttg gaagtataat ggcaaacagc
    38341 gttgtcgagt tttttaagga agacaaaaat atgaacgtta taaacaagtt aaaaaatgta
    38401 ggagtaaata caaaatcatt ggataataca ggtgaaaaag tagaaaaaat atttgaaggg
    38461 atgaaaatcg tattgactgg tacacttcct acattaaaaa gaaatgatgc aaaagatatg
    38521 atagaaaaaa gaggtggaaa agctacatct agtgttagta aatcgacaac atttgttttg
    38581 gcaggtgaag aagctggttc taaacttact aaagcaaatg atttaggaat taaagttata
    38641 gatgaagaga gatttttaga attattaaag ttatcatcga aagatgaagt aaaagctgta
    38701 ttagagagtt aaaaagtcgc ttaatttagt agaaaactac tataattaat gatagaatag
    38761 ttcagtaagc taataagatt acgaaaaatg acaataatta atatttgaca aaattaaaaa
    38821 ttataaaaat aaatttataa aaaataaaaa atatgagaaa ggatataaaa aatgaccaga
    38881 agttatgata gaagtaacga acagataaga cctgtaaaga taactagaga ttatacaaag
    38941 tatgcagaag gttctgttct tatagaaatg ggagagacaa aggttatatg cactgcatca
    39001 gtggaagaaa aagttcctcc ttttttaaga aatagtggta ctggatggat aaatgctgaa
    39061 tattctatgc taccaagagc aacacaacaa agaaagataa gagatgcatc taggggaaaa
    39121 attgatggaa gaacacaaga aatacagagg ttaataggaa gagcaataag gtctgttgta
    39181 gacttgaata aattaggaga aagaactatt tgggtagatt gtgatgtgat tcaggcagat
    39241 ggtggaacta gaactgcatc tataacaggg gcatttgtag cagttgcaga agcaatatat
    39301 aaattatata aagcaaagat aataaaagag atgccaataa caaattttgt gtctgcaatt
    39361 agtgttggta ttgtaaatgg aatacacatg ctagatttat gttatgaaga agattctaaa
    39421 gcacaggtag atatgaatat aataatgact gataagtgtg agtttgtaga agtacagggg
    39481 acaggagaag agaaaccttt ttcgagagca gatttaaatt tattgttaga gttaggtgaa
    39541 aaagggaata aagaattaat aaggcttcaa agagaagctt taggtgaaat atcagatgag
    39601 atattgggta tggattatgg taatgaagta gtgattgcta ctaataatgc tcataagcta
    39661 gaagaaatag gtgaaatctt aaaagatttt gaatataaag tgtactcttt aaaagatgtt
    39721 gatttagcag gtatagagat agtagaagat ggaaaaacat ttgagcataa tgcgttgata
    39781 aaagctagaa caatagcaaa aaagactaaa cttatagcaa tatcagatga ttctggctta
    39841 gaagtagatg ctttaggcaa aaaacctggt gtttattcag ctagatatgc aggagaacat
    39901 gcaacagatg aagaaaatag aaaaaaactg ttaaaagcta tgcaaaatat accaatgagc
    39961 aaaagaaatg caagattcgt ctctgcaata gcagtagttt ttcctgatgg aaaagaattt
    40021 gtagtaagag gaatttgtga aggaatgata ggatttgaag aaaaaggtaa aaatggtttt
    40081 ggatatgata gcttatttat agtaaaagga tatgataaga cttttggtga aatacctagt
    40141 gttataaaaa attcaatcag tcatagagca aacgcactaa aacttatgaa acaagagttt
    40201 ataaaaaggg tagtgaagta atgaaaatag gcatagtaag cgacacacat atgatgatta
    40261 aaaatatgga aaaaacaata ccatatttga aagaatgtga cctaataatt catgcaggag
    40321 ataactttac tgattcaaga tatattcata gcatgactaa tgtaggtatt attgcagtta
    40381 aaggtaattg tgactttgat gctgttgagg aagaagttgt ctttgaagtg gcaaataaaa
    40441 ccatattctt atgccatgga gataagtatg gcgtaaaata tggaactcat atgttagaaa
    40501 aaaaggcaac tgaagttgat gctgatatag ttatatttgg ccatacccat accccattta
    40561 gagaaattaa agatggtgta ctttacataa atcctggaag cacttcactt ccaagaggag
    40621 tatcgtataa aagttttgtc attatggata tagaagaaga tgacataaaa attgaagaaa
    40681 tacgcatata aaggtgtatt tatctaaaaa aatggcaaaa aacgctcaaa aaattaaatt
    40741 ttatcaaata agtacaacga tattaatgga acacttgtaa ataaaaaaac ttatgtgata
    40801 taattaagtg gttgaattat aaatagaatg aattataata ccgttatcgg gtattacata
    40861 aatatcacta ggaggattag aaggatgaaa gcagaactaa ttaaaaaaga gggtaataaa
    40921 gttactttaa aaataacagt agataacaat aaatttgaag cagcagtaaa taaggcttat
    40981 aataaaagca gaaataaata caatatacct ggatttagaa aaggtaaagc tccaagaatt
    41041 gttatagaga ctcaatacgg aaaaggtata ttctacaatg atgctataga aatattattc
    41101 ccagaagttt atccagaagc tatcaaggaa ttagacatag acccaataga caatccagat
    41161 ttagatatag aagaaataag taaagacaat gggttggtta tggttcttaa tgtagaagtt
    41221 aaaccagagt ttgaattagg aaactacaag ggtatagaaa tagctaaggt tgagaatact
    41281 gtaagtgacg aaaatgttga tgctaaacta caagaaatgg ttgaaaaaaa tgccagatta
    41341 gtaagtgtag aagacaaagc tttagaagat ggagatacag ctataataga cttcgaaggt
    41401 tttgaaaatg gtgtagcttt tgatggtggt aaaggtgaaa attataactt agttataggt
    41461 tcaaacacat ttataccagg atttgaagaa caattagtag gtaaaaaagc tggtgaagaa
    41521 gtagaagtta atgttacttt cccagaagaa tatcactcac aagatttagc tggaaaacca
    41581 gttgtattta atgtaaaaat aaatgatgta aaagtaaaag aattatctgc acttgatgat
    41641 gaatttgcta aagatactag tgaatttgat tctttagatg aattaaaagc agatgtaaga
    41701 gctaagttag aagaagaagc taaaaataga gcagatgcag aaactagaaa ttcagtagta
    41761 gaaaaagttg ctgaaaatac agaaatagaa ataccagaag ttatgataca acatcaaata
    41821 gataatatgt taaatgaact taactaccaa ttacaatatc aaggatttgg attacaacaa
    41881 ttactagaga tgactggtag aactatggaa gaattaagag aagagagaaa agaagatgct
    41941 aaaaaattag ttaagtcttc tttagtatta gaagcaataa ctaaagctga aggaattgaa
    42001 gcaacagaag aagaatttaa ggctgagtta gaaaaaatgg cttctgctta caatatggaa
    42061 gtagaaaaaa tagaagcttc tttaagagat gccgacaaag aagatataaa aggtcaaata
    42121 aaaataagaa aaacaataga tttattagtt gataatgcaa caatagctta ataaaataaa
    42181 cgctaactaa tatagttgac gttatgaaat gtttagtata taatgatgtg caaatataat
    42241 ttagttaaat gcgtataata atttacagta gcttaaaaaa agctactgta aattatatag
    42301 aataaagggg gtatgaaacc atggcattag tacctgtagt tgttgaacaa acaggaagag
    42361 gagaaagatc ttatgatatt ttttctagac tattaaaaga cagaataatc ttcttaggag
    42421 atcaagttaa cgatgccaca gcagggctta tagtagcaca gctattattt ttagaagctg
    42481 aagacccaga caaagatata catttatata taaattctcc aggaggaagt ataacttctg
    42541 gaatggctat atatgatact atgcaataca tcaaaccaga tgtaagtact atatgtatag
    42601 gtatggctgc ttctatggga gcattcttgt tggcagcagg agcaaaagga aaaagactag
    42661 cactaccaaa tagtgaaata atgatacatc aaccattagg tggagctcaa ggtcaagcaa
    42721 cagatataga aattcatgca aagagaattt taaaaataaa agaaacttta aatgagatat
    42781 tatctgaaag aactggtcag ccattagaaa aaattaaaat ggatactgaa cgtgataact
    42841 tcatgagtgc actagaagcc aaagaatatg gtttaataga tgaagtattt acaaagagac
    42901 cgtagataga gagaggtgtt aatatgtcta aatatgaaga aaaacgacaa ttaaagtgtt
    42961 cattctgcgg taaaaatcaa gatcaagtaa gaagattaat tgcaggtcca aatgtatata
    43021 tttgtgacga gtgtgttgaa ctttgtgacg aaattattca agaagagata gaagatacta
    43081 tagatgagga tactacatct ttaccaaaac caaaggaaat gatggagatt ctaaatgatt
    43141 atgtaatagg tcaagaaaaa gctaaaaaag ctttatcagt tgcggtttat aatcattata
    43201 agagaatata cagtaaaaaa tctagtagta aggatataga aattcaaaag agtaatatac
    43261 ttttattagg acctacaggt tctggaaaga cattacttgc tcaaactcta gcaagaactc
    43321 taaatgtacc ttttgcaatg gcagatgcta catcattgac tgaagctgga tatgttggag
    43381 aagacgttga aaatatactt ttaaaactta ttcaagctgc tgattttgat atagaaaaag
    43441 ctgaaagagg tataatatat atagatgaga tagataagat tgcaagaaaa tctgaaaacc
    43501 catctataac tagagatgtt agtggtgaag gtgttcaaca agcacttcta aaaatattag
    43561 aaggtactgt tgcaaatgtt ccaccacaag gaggaagaaa acatcctcat caagaatttt
    43621 taaagataga tactactaat gtattattta tattaggtgg agcttttgat ggattagaga
    43681 agataattca aaaacgtggt ggagataaaa cactaggttt tggagctaaa atagaaagta
    43741 aaaaagaatt agatttaggg aagctatatg aaaaagtact tccagaggat ttattaaaat
    43801 atggtataat accagagttt ataggaagaa taccagtttt agctacttta gagttgttgg
    43861 atgaagatgc attaatgcag atattacagg aacctaaaaa tgctctagta aaacagtata
    43921 aaaagttatt ggagttagat gatgttgagc tagaatttga agaaggtgct cttcgtgcaa
    43981 tcgctaaaaa ggccatagaa agaaatacag gagctagagg acttagaagt atagttgaaa
    44041 gcgtaatgat ggaaactatg tttgaagtac catctagaga taatataaag aaggttatag
    44101 taacagagaa atctgtgaac gaagactcag taaatcctat catagtactt aaggatcaag
    44161 aggaaagtgc ataagatgat gaaaaggagc tttaaaagct ccttttttta tgttaatatg
    44221 ctaaatataa aataggtatc attattataa aaatgtgagt aatataccta gaataccaaa
    44281 gacgaataca attgcaatgg aaccaatttt tcctttatat aaaagataaa atgatgctat
    44341 aaatgcaatt attccatata aatcccaatt aacttctttg gcagatgaaa aagctgctga
    44401 taatatgaat cctagagtaa ttggtctaag aactgtcaat aagttttcta cctttttatt
    44461 atttttaaat ttagaaaata actttgatat aatagttaga cctattaatg caaaaattgt
    44521 aacaccaata gttgcggcta gagaaccaaa gaagccagca gtcttaaatc ctacaaatgt
    44581 agcactattt attgctacag gacctggtgt agattgtgat atagcaagta aatccaaaaa
    44641 ctcttgatta gttataaagt gatatttaga tataaattct tgctggataa atggtagcat
    44701 ggcataaccg ccaccaaaac taaatgcccc tattttaagg aatattaaga agagtagtat
    44761 tatttctgac atagactata tacacctcct ccaattatta aataaatagg gcttatattg
    44821 aatacaccaa cagataaaac tgctataatt aatagtagta tgttagtttt agactttggt
    44881 agtttcttga acatgctcgt aaaagaatac aatataagag ctattacaac aggcgcaact
    44941 cctttaaaaa atccatctaa aattttagat gatgaatttt taaagtatag atacgataag
    45001 actaagacta tacaaaatga tggtaaagca gagcctaagg tacatataag aactcctggt
    45061 ataccataaa gtttatatcc taataataca gatatattaa ctgccagtac tccaggataa
    45121 ctttgagcta tggataaata atcaataaat tcttcctgct ctaaaagttt ttgtttgttt
    45181 acaagttcat cttgtataag aggaaccata gcgtatccac caccaaatgt aaacgcacca
    45241 atttttaaaa aggttaaaaa caatttcaac ataatagaaa cctccaaaag ataaataaca
    45301 tctaagtata ctaatattaa tattatatca taataaaaag ataatatagt atgatagtat
    45361 tctaagaatt tatcattaat gttgaaaatt aacttgttca aatatataat attaaaagca
    45421 aagcaattag actagaaaag gagtaatgtt gatggaacaa aattatacta aaatagatca
    45481 tgaattacca ttaattcctc taagaggatt agctatattt ccatatatga tattaaattt
    45541 tgatataggt agagagatat ctcttaaagc tttagaccaa gctatgatgg atgaagaact
    45601 tatattttta acttctcaga aagaagcaga ggtagatgag ccaggagaag aggattttta
    45661 tcatgtggga acaatctgta aagttaagca aatgataaaa ttaccaggag atacagttcg
    45721 tgttttggtt gaaggtgtat caaggggtag agtaaagaaa atagaacaag aagatgggta
    45781 tttcagagca gtaatagaag aaatagtatt tgatagtgat aatttggata gtgaaacaga
    45841 agttgaaatt gaagcatttg taagaaatgt atttgatgcc tttgaagagt atataaatat
    45901 tggaaatagg gtatcaccag aaatattaat atctttagct gatatagaag atgtagatag
    45961 atttatagat acgatagctg caaacatata tctaaaatca agccaaaaac aagaaatatt
    46021 agaagaattt gatattagaa aaagacttga acttatttat tctatattat tagaggaaat
    46081 agatatatta aaaatagaaa agaaaataac tttaagagta aaaaaacaga tgaataaggt
    46141 tcaaaaagaa tattatctta gagaacaatt aaaagctata cagaaagaat taggtgaaga
    46201 agaagatata aactctgaag cagatgagta tagagaaaag cttaaaaaaa taaaagcacc
    46261 taagacaact aaagagaaaa tagaaaaaga gatagataaa ttttcaaaaa tatcttctat
    46321 gtctccagat gtatctgtaa gtagaaacta tttagatact atattctcat tgccatggaa
    46381 taaagagaca aaagataaat tagatataac taaggcaaaa gatatattag atgaagacca
    46441 ttatggatta gaaaaagtta aggagagaat actagagtat ctagctataa gaactcttgc
    46501 taagtcactt aaagggccta taatatgtct agttggtcct ccaggaacag gaaagacatc
    46561 tatagtaaaa tcaatcgcca gagcattaaa tagaaaattt gtaagaatat ctttgggtgg
    46621 agttagagat gaagcagaaa taagaggtca tagaagaact tatgtaggtt caattccagg
    46681 aagaataatt aatggggtaa aagaagccca aacaaaaaat cctgtattct tatttgatga
    46741 gatagataag atggcagcag attataaagg tgacccagct tcagcaatgc tagaagtatt
    46801 agacccagag caaaataagg attttgtgga ccattactta gaaatacctt ttgatttatc
    46861 aaaaatacta tttgttacaa cagcaaatag tctaagtaat ataccaagac cattattaga
    46921 tagaatggaa gtaatagaag tatctggata tatagaagaa gaaaaattaa atatagcaaa
    46981 aaaataccta cttccaaaac aaattaaaga acatgcttta aaagaaaact ttataaaaat
    47041 agatgatgaa actttaagaa gtataatcaa ccattataca agagaagctg gtgtaagaac
    47101 actagaaaga actattggta agatttgtag aaaggttgcc aaaaaatacg ttgaagaccc
    47161 aactcttgaa gaggttgtta taaataagtc tgacctagag acatatcttg gaaaagacat
    47221 gtttaagtat caacttgcag aagttaaccc tcaaatagga ttagtaaatg gtcttgcgtg
    47281 gacagaagtt ggtggagtta cacttgaagt agaagtaaac gtacttaaag gtaaaggcga
    47341 aattgtatta actggaaaat taggagatgt tatgaaggaa tctgcgaaga caggtatctc
    47401 ttatataagg tcaatagtgg acaagtttga tatagaccct gaattttata agacgaatga
    47461 tattcatata cacattccag aaggtgctgt tccaaaagat ggaccatcag ctggtataac
    47521 tatggctctt gcagtaatct cagcacttac taaaagacct gtgcctggaa atatagcaat
    47581 gacaggagag ataactttaa gaggtagagt cttagcagta ggaggagtta aagaaaagtt
    47641 attagcagct catagagctg gtataacaaa agtattaatt cctaaagaat gtgaagctga
    47701 tttagatgaa ataccagaaa atgtaaaaga aaaaatggag tttgtgcttg tagaacatat
    47761 ggatgaagta ttagaacaag ctttattaaa gagtggtgaa aataatgaaa attagaagtt
    47821 cagagataac tatgagtgct gtgaataaat cacagtatcc agcagaagga atcccagaga
    47881 tagcattggc tggtaggtca aatgttggaa aatcatcaat aataaataca ttgcttaaca
    47941 gaagaaactt tgctagaacc agtcaaacac caggaaaaac tagaactata aatttttatc
    48001 taataaataa tgaattttat tttgtagacc ttccaggcta tggatatgca aagatagcta
    48061 agtctgaaaa agaaaagtgg ggaggtataa tggaacgata tctagaaagt agacaagagt
    48121 tatgttctat attcctactt gtagatatta gacatgagcc tacagcagat gataagctta
    48181 tgtatgaatg gataaagcac tttggatata actgtgtagt tattgcaact aaggcagata
    48241 aaatatctag aggacaatat caaaaacaca taagtataat aagaaaaaaa ttgcaaatgg
    48301 aaagtagtga aaaagtaatt cctgtttctt cactaaaaaa gactggtgtt gaagaattat
    48361 gggaagagat tgtaaatcaa tacaatcaac atggatatga aataacagta gattaaattt
    48421 aaaatgttaa atattgacat aagatttatt tgaataataa atgtaataat agttagtttt
    48481 aattatatta atattaaagt aaaatatagg atgccttaaa atagttttaa tgaacttttt
    48541 tttggcatcc ttattgttta taaacaataa atatcagtaa ttttgctaaa tactaataaa
    48601 ttttagtaag gtatgggaaa attagtataa aatagttaaa ctaaaaaatt attgatttat
    48661 gtagtcagta ataaatagca tttaagaaat agatttatct gttttcctca taaagaaaac
    48721 agttagtata agccctacaa aacatactga tgctgcaatc caataagact gattgctagc
    48781 tataacatag gctgatgtgt gacttttaaa cttttgattg tatgtaagac tttgtgcaaa
    48841 aaaactacta aaaaatgctg ttccaagagc aaatgataaa ttacgaatag ttgcaagaaa
    48901 actgcctccg tacccctgtt tttgaggagg aacatctgct aaaatactac tattgtttgg
    48961 tgaactaaat gctcctagcc caagtccaaa aataactaaa catacaatta aaaggtacaa
    49021 tggagaatct gcttttaaaa gtgccattcc aactagtgag atggtcataa atgaaaaaga
    49081 tgctgttaga atgttttttg caccgtgttt atcagaaagt gaacctgcaa taggtgctat
    49141 aagtaccata ataagtggat gtacagtcat tacataacca gccatcatag gagataaatt
    49201 ttttaattgt tctaaataaa atggaagtag aaaagatact gccatttgag gaaaataaca
    49261 agctactcca atgatattgc ctacagtaaa gtttctattt ttaaatagag ggaggtcaat
    49321 aaagctttgt tcaaatttta cttctcttaa tgccaacaat aagaagatta taagtgctgt
    49381 tatacctaaa tacaatcttg tattaccctt ctcattcatt gcaagtaata taagcgtagt
    49441 gcaagatgcg aaaagtagaa gacctggaat atcaaagctc ttgttttgtt catccaaaac
    49501 aggtttaggc agaaatttaa tgccaagaaa gactgctata ataccaatag ggatattgat
    49561 aataaaaata gaaggccatc caaaatgttc taaaattata cctccaatta caggaccact
    49621 catatttcct ataccaacta cagctccagt gattcctata gcttttcctt tttcatttgc
    49681 tggaaatgca ttggaaacta taccaagccc agtagccatt aaaatacttg ctccaactgc
    49741 ctgaaagatt cttgaagaaa ttaatgttga taaattgttt gacatactac acagaaaaga
    49801 acctattgta aatataaaaa atcctaatgt gtatagacga tttgaaccta ctttatcgcc
    49861 aagttttccg aaaaataaca tagtagctgt tacaacaagc atataagctg ttacaaccca
    49921 ctgaatttgt gacatgttaa ttttaaagtc agcagcaatt gtaggatttg cgatatttag
    49981 tatacttcca tcaagagtag acataaatac accaatacag atgataatca atactatcca
    50041 tttttgtttc atgataacac tccaatctta atagatttta taagtacgat ataattgtaa
    50101 aataaacaac aaaaaaagca cctgtatatt aggtaccttg aatgtgtcta atttcatgaa
    50161 taaatacggt agttgaagga tttgtataga ttactcatgt aaaattacat aaaggtactc
    50221 atatactatt ttcttctacc atccagattt tactgtcggc tttggaatat gaccaaatta
    50281 tgccataagg ctcgcgggct tttaccgccg ataggtaatt tcacccgttt atgaagaaaa
    50341 acagatgtat tttgtaatat tattttaaca taaaattata atggaaacaa ttggatttaa
    50401 gtaatatcca gctgtattac aatacaaata tttcaatatg gacacttaaa ttgtatttat
    50461 agatagaata aggcacagta tgagaatcta taataattag ataaaattaa cctgttatta
    50521 gtattagatg gcaagtttta aatttgtcaa aatcagaaag ctgtaataaa attcttataa
    50581 tatgaatatc ttaattaaga gatattgtaa attatgagga ggcgctaata tggaaggaaa
    50641 ggtaaagaag gcattcccgg gtggaaatac atcacaaggc tcatattctt tttttgacta
    50701 tataattcct gaaaatgtaa aaagagtttt ttgtttaaag ggtggacctg gagtaggaaa
    50761 atcctcactt atgaaaaaaa tttataaaga gtttttgcat agaggatatg atattgattt
    50821 atatcattgt ccttctgacc caagttcgtt ggatggttta gttataaaga aattaggcgt
    50881 ggtacttatg gatgcaactg ccccacatac tatggaccca aagctacctg gagctttgga
    50941 tgagataatt aatttaggtg attactggaa tacagaagaa ttagaaaaga ataaacaaga
    51001 aatatcagtt tatgataaag atattagtaa ttcatttaaa agagcattta agtttttaaa
    51061 atcagcagaa ccaatcttta gagacataga agaaaaatat tctgattgta tggattatgg
    51121 caaagtaaat ttggtcacag aagaatttat aaaaaggtta tttgatggag ttaaaagcac
    51181 aggaaatcta aaaagagaaa agcatttatt tggttcagct ataactcctg tagggtgttt
    51241 agattataca gaaaacattt taaaagatgt aaagaaagtc tattatttag atggagaaat
    51301 aggaactggg aaaactacat tattaaacaa agtatataag aaagctattg aaaaaggttt
    51361 aaatgtagaa gtttatcatt atccacttat tccagagaaa attgaaactg tactattaac
    51421 tgatttagat ataggcataa ctataagtac gacttttaaa gaagaagata caattgattt
    51481 aaatcagttt ttaaatagag aaaaactact taaatatgaa gaagatatta aatttgatga
    51541 aaaagtttta gatgatttaa tttgttgggc agtactaaat cttaagagag ccaagtctaa
    51601 acatgatatt atagaaagtt actatagtcc taatatgaga tttgatgaag tagggaaatt
    51661 aagagataaa ttaattaaaa gaattttaaa atatgaggaa aacttataaa cgtatatgtt
    51721 taaaattaat gttaataatg atataatttt tagtaaattg gtgtagcttt gaggctatgc
    51781 cattttactt ttttttgcta aaaaatgata ttaataatct ccaaagcaat tatttgtttt
    51841 tcataattat tatttccttt cctaatttat gtttttttat aatatcaaaa caatgtttat
    51901 tgaaagttta tataatttta agaacatcta aaaatgcata cttgatattg gtaaattagt
    51961 gataggagtt caatgtatga tattatatac taaagatgaa ttttaatata taactttgat
    52021 ataataagca tatgtaaatg tttaatattt aattaaagaa aattatcata taaaaataaa
    52081 tttgtaagga gcaatacagt atgaaaaaac aatatgtgtt tataatacta gcaagtacta
    52141 ttttaggtat acttgttgga accatattta gagattatag caatgaagaa acagtttata
    52201 caagcaaaga caagtcaata agaaaagaaa taaaaatgac aagaaaatct ataaaagaat
    52261 taaccaaaga gaaagacaag ttagataaag aaattaattc aatgaaacaa aatcaaaaaa
    52321 attctgaaga aatatcagaa atagaaacac ttagagatag tctatcatat tcagatgtaa
    52381 agggtagtgg gataatatta agtatagatg ctatagatga aaaaacaggg aatatagcta
    52441 atagtataga ctataataag attcttgtaa aagttataaa tgaattaaaa gtaaacggag
    52501 gaaaatacat agaaataaat ggtcaaagaa ttaatcaata ttcagaagtt gtacttgcag
    52561 gaagccatat aaatataaat ggagttcctg tagcacaacc atatgaaata aagtgcattg
    52621 gagataagga gaaactatct aattatgtag ataaaggtag taaatattta gatagcatac
    52681 aaaccaatta tccaatgaaa ataagcataa aaactgaaga aaatatctct atgaaaaaaa
    52741 tgaatatacc taataaatta aagtatataa agggtgatta agattatatt agaggaaagc
    52801 agtttgccaa tgttaatacc agaaaaactt gcaaaaaaat ataatgtatt tccagttgag
    52861 tttcaagatg ataatttagt tgtagaaata gaagatgagg atatttatgc tctacaggac
    52921 ttgagattag ctacaggtaa agaaattata ttgaagaagg agaaaaaaga acttataagt
    52981 gaaaagattg aaaaatatta taatagcttt gaacttgatg aggattatgc aaaaaaatta
    53041 tttgaaaatc ttttagaaaa agctataaaa gaaaacgcaa gtgatataca tatagaacca
    53101 tttaaagaac atttaatagt gagaatgagg gtagatggag aactaaagga agtatcaaag
    53161 tttttagttg atgtctatcc atcattgtct acggttataa aattaaaggc atcaatggat
    53221 ataacagaaa aaaggcttcc tcaggatggt agggtggata taaagttagg tggaaattta
    53281 attgacatta gagtttcatc aataccaact gtctatggtg aaaaaatagt tttgaggata
    53341 cttaatagag atactttttt aaaagacaaa ttagaacttg gtttttcaga ggaagctata
    53401 aaatctataa atcgtataat aaataaaaga gcaggaatat tattagtgac aggtcctaca
    53461 ggtagtggaa agactacaac agtatattcc ttattaaatg atttaaaagg aataaataaa
    53521 aatattatga ctatagaaaa tcctgtagag tataagatgg atggcataag tcagattcaa
    53581 gtaaattcaa aagtagggtt gagctttgat gtaggtctta gagcgatatt aagacaagac
    53641 ccagatataa taatggtcgg agaaataaga gatgcagaaa cagctaagat agcagtaaga
    53701 gcagctataa caggtcattt agttataagt actttacata ctaatgatgc agtatcttcc
    53761 atagctagat tactagaaat gcaaatacca ccatatcttt taaatgcttc tcttataggt
    53821 gttatatctc aaaagttggt tagaaaagtc tgcaatcatt gtagccatga gattatgata
    53881 aaagataatt ttagtggaga tgtaaatact aaggtagctg tagggtgtga aaaatgtaat
    53941 gataaaggat actttggaag aacagcaatt tatgaaatct tagaaattaa tgatgatata
    54001 aagacatgta taagaaatat ggaggattct agtactatta aagatgtagc acaaaataat
    54061 ggaatgataa catttgaaga tagttgtaaa agactaataa atgaaaaaat aacgacatta
    54121 gaagagtgtt tagtagtaaa tgaaatgatt taactgaatt gtatagttaa acttcgtttg
    54181 gtcagttgtc tttatttaat ctattttaat taagatgttt gagtataaat tatatttaag
    54241 tgaaataaaa ttaaatgcat taaattagaa aatattaagt ttatttaatt gtaattaata
    54301 taatttggaa ggtattatag tacatgagat tatctaaaaa tatattttat aatttagaaa
    54361 agttttattt agtattaaat agaatcagtg ataaagaaat tagagtaatt tgcaaagaga
    54421 taggcatatt gctggaatct ggatgtgaaa ttacaaaaat atttgaaatc attgagagtc
    54481 agtcaagtaa aaaagcaaag aatttgctta gtatagtatc aaatcatatt caaaaaggta
    54541 actcaatagc agaatcattt caaataacag gtatattttc taaattcttt ataagtatga
    54601 taaaagcagg agaaactagt ggaaacttag atataataat gagtgattta tctaattatt
    54661 atgataaaga atacaaatta aaaatgaaaa taataactat ttcaatatat ccaataatac
    54721 ttataatatt atctatctta tcaatgttgt ttatattcgt atttgtaata cctaattttc
    54781 aggtggtttt taccaacaat ggaattgaac cacctttaat aactagagtt ttaatgggaa
    54841 tatctacagt ggttacaaat aacttagctt atataatatt tagttttata ttgttttcaa
    54901 taggaagcat ttatttcttt ataacaaatg ataatataaa aaaattgatt aattcgttaa
    54961 aattcaaaat accttttata aaaaaaatta atcagttagt agctacaaca agattttcaa
    55021 gggcattgtc cgttttaatt agcagtggaa tacaaattgt ggaagctata gacatgtcag
    55081 ctagtgttat agacaacgaa tttatttatg aaaggttaaa gatttccaat aattatataa
    55141 aaaaaggaaa tagcataggt aaatctttga atttagcaaa tgtttttcca aaattattta
    55201 tttcaatggc aaatacagga gaagaaagtg ggaaactaga taaaagtcta aatgtaataa
    55261 ataaatttta tgaaaatgaa ttaaataaca aaatagagca aataatgaaa tttatagaac
    55321 ctatgctaat tgtatttatg ggattaatta ttggtacttt tattttagca atggttgttc
    55381 ctatgtttga tgcaattact aatttttaga gagaaaaata aattttatta gatgaaactt
    55441 ttgaaaagga gagaatattt aattgataaa tttgataaat aaaaaacgaa aaggatttac
    55501 acttgttgaa atgattgtag tagtaactat tttaggcgtt atatctagta tagcattagt
    55561 taagtatagt aaggttcaag aaagtgccaa attaaatgca gactatacga atgctgctaa
    55621 tatagtaacc gcagctagca tggcaattaa tgatgatgaa aagacaatag actctctaag
    55681 tgtagagaca ttgaaggaaa agggatacct aaatactgtt ccagttcctc agagtacatc
    55741 aggtaaattc gaacttgtca taaatgatag cggaacagat ataagcgtaa atataaattc
    55801 taagcaattt tatccaaaat aatattttat attgattgct gtaagtttta aaattatttt
    55861 tatttaagaa ggagatggct ataattaaaa aaattctaaa cttagaaata aatgatgatt
    55921 atataaggct tgtattttta agaaaaagtc ataaaaaagt ttttatagat aaatcaatta
    55981 taaaagagat taactttgat ataaaaaatg atagtaattc gattgagaag attaaatata
    56041 tagaagatgt agttagattt gtaaaagagg agattggtaa atcaaaaata ttatataaaa
    56101 atttatactt taacattcaa attcaggata tagtc
//
LOCUS       DAJMZY010000012        55934 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.012, whole genome shotgun sequence.
ACCESSION   DAJMZY010000012 DAJMZY010000000
VERSION     DAJMZY010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 55934)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 55934)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..55934
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.012"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            complement(483..896)
                     /locus_tag="OE968_000711"
     CDS             complement(483..896)
                     /locus_tag="OE968_000711"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HCP7218026.1"
                     /translation="MNIALVAHDQMKNTMVGFCIGYESILKKYGLYATGTTGKRIMDE
                     TELNINRLASGPLGGDQQIGSLIVTQEIDLVIFLRDPLTSQAHETDIQALIRLCDVYH
                     VPIATNLASAEIFIKALDRGELSWREVRKSKSQRI"
     gene            complement(937..2067)
                     /gene="rodA"
                     /locus_tag="OE968_000712"
     CDS             complement(937..2067)
                     /gene="rodA"
                     /locus_tag="OE968_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein RodA"
                     /protein_id="HCP7218027.1"
                     /translation="MKKININYKSTIKLIKQLDWKLIVTVLAIFIFGLVILSSATHAN
                     STGSYNQLIKQGLAFVLGIGMIIVILFFDYNLLGRYYKALYIISLILLAIVLLPGIGT
                     VKGGARSWINLGPLDLQTSEIVKLTFVLSYAKILESKKDKLNTLKEVMPVVVYSLPFI
                     GLLIAQPDLGTGIVFCCMIFAMLFTAGLSSKLIKRGIIILLVSMPLMYLMMADHQKVR
                     IEAFLNPEDVTLKGNYQVMQSLIAIGSGGVTGKGLYNGSQNQEDFLPVQDSDFIFAVV
                     GEELGVIGMAVLIILFMIFLLRLLAIARDAKDFYGTLIVVGVMGMFGYQIIQNIGMTV
                     ALIPVTGVTLPFVSYGGSSLLTSLANLGLVLNVCMRRKKINF"
     gene            complement(2152..2436)
                     /gene="minE"
                     /locus_tag="OE968_000713"
     CDS             complement(2152..2436)
                     /gene="minE"
                     /locus_tag="OE968_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division topological specificity factor
                     MinE"
                     /protein_id="HCP7218028.1"
                     /translation="MLDLFRVFSNEAKTSKSVAKERLKLVLVHDRVDCSPQLLEMIKT
                     DILKVIANYAEIEDDGLEIKMSKCRGEHDDKPVSALVANIPLKNIKDRCM"
     gene            complement(2454..3251)
                     /gene="minD"
                     /locus_tag="OE968_000714"
     CDS             complement(2454..3251)
                     /gene="minD"
                     /locus_tag="OE968_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum site-determining protein MinD"
                     /protein_id="HCP7218029.1"
                     /translation="MSEVIVITSGKGGVGKTTTAANLGTALSLENKKTVVVDADIGLR
                     NLDVVMGLENRIVYDIVDVVEGTCRLKQALIKDKRFDNLYLLPAAQTRDKNAVSVEQM
                     IDLCEKLKESFEYIIIDCPAGIEQGFKNAVAGADRAIVVTNPEISAVRDADRIIGLLE
                     ANEIKEIRLVINRIRNDMVKRGDMMDKQDIIEILAIDLLGLVPDDESIIISTNKGEPA
                     ILDSKSLAGQAYKNIAKRILNEEVPLLDLEVEDGFFGRLKKMFSMAK"
     gene            complement(3275..3958)
                     /locus_tag="OE968_000715"
     CDS             complement(3275..3958)
                     /locus_tag="OE968_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum site-determining protein MinC"
                     /protein_id="HCP7218030.1"
                     /translation="MSLREICSQELVEFKGNKRGIIVNIKREAPFEEIQEKIINKLEA
                     YVGFFNGAKISKINSDCLTDMEILELKEGITSRFDVEFVEDQKIEENSNFPTKYVNTL
                     RSGENIEFEGDVVILNDMKPGSKVLSKSNTVVMGDINAGAKVVAGGNVFVMGKIEGFV
                     HAGAEGNEFAYVVAGNLNPKILQIADNIAEAPDDEENYESESEISPEIAFVSNGRIVI
                     ESYLSKLDK"
     gene            complement(4056..7034)
                     /locus_tag="OE968_000716"
     CDS             complement(4056..7034)
                     /locus_tag="OE968_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HCP7218031.1"
                     /translation="MEENKQVDRLKIIKIVMGVIFLAILVKIIYMTTFKYEYYNELAE
                     NKTYKKLAIEAPRGEIKDRYGRLLAGNKNLFTVQVSGNDINKKDANKHSRANEISLKL
                     INLLERNGEEYVDEFPIYVENGKYYYTYDRDIREYKSENGIPNDYNAKESFYYLVDKL
                     ISAGILSQEDKRLDATRLQAKLNENGYYPPILVSKWMFTAERDKRDWLASYKIKETKL
                     SAKEAFEKVRNSDALEIDKSLSDEDARKIMVVRDLIKSKGYSQYNPVTIAKDVGETTI
                     AQIEESAMDLVGVSIAVEPVRYYPNGSLASHMLGYVGKMPSTQIESYLQKGYETGDMV
                     GLAGVEKSNESRLRGTDGYKMVKVDALGRISKEIESKKPKSGDTVYLTLDKDLQEVSD
                     NALKQIIEVASKGGTFKSKFGDKPISAYAGKAQSAALIAIDVKNGEVLASSSYPNYDP
                     NKFAKGISTEDYKALQPKNPNDLLAGSPLLNLVTQGEFQPGSSFKMVTSMAALENGLD
                     PNFTINDPGVIMLGKKSFGDYVWNHGRGNHGMTNLYKAIQESCNIYMATIGTGKTWPD
                     GKSIGIDMNANKILEYAKLFGLDQNTGLQDEVEERAGKVPSTEDKLKSTQALLKSNLE
                     REMANDFVDITREKNPKEYEKRINEIVSWAAEKKTPGRVETMNRLKKLDVKEDRIEEV
                     ADLAVFSYFNFAKWSTADTFNLAIGQGENAYTPAQISRYVAAIANGGNLVELSVVDRA
                     VSSDYSSVKINDQKKVEKIPFKNPDNLKELTKGMKLVARQGTAKSAFADFPIDVAAKT
                     GTAEKSGKIPTDNEYEYLKSHMSSYNVNLNDAIKLADKMKAEKEKELSLAKEKEIKKK
                     LENKDLKDEERKKLEEELEDGVKVRLEDTDKVNSSYLRKAIKELNPKITDDQIDRFKQ
                     DYGSFTWTVAFAPADDPEIAVVCVIPQGDSSVFSLLPTREVIGTYMGLEPTNSKNDNK
                     TNDVNNSSDENINFESQINR"
     gene            complement(7046..7534)
                     /gene="mreD"
                     /locus_tag="OE968_000717"
     CDS             complement(7046..7534)
                     /gene="mreD"
                     /locus_tag="OE968_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HCP7218032.1"
                     /translation="MKKVLLCLLGIVLMTIENSITNYIDIFGISFNLVLIYVTIISLY
                     LDELEGGIIAAIIGLIKDITVGGIFGVNALILFIIAYAIGYMRDQLYKGSYIITFVLI
                     FIGSLIDSIVNIGTSSIIYQSYNISTLFVKGLLVAPIVNSLIGLVIYRLSKRAVLKLK
                     ED"
     gene            complement(7549..8442)
                     /gene="mreC"
                     /locus_tag="OE968_000718"
     CDS             complement(7549..8442)
                     /gene="mreC"
                     /locus_tag="OE968_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HCP7218033.1"
                     /translation="MALRFDKNKNEKKRINVKVIATGVVAITLIGIVGISIGKFSSGS
                     PVNLGVASDAITSVGKGINDGFSFIKNGFKDVANFKDNSKKVKKLEEENEKLKKNMIA
                     LNAKLDKTESLEELKKTLNFVQEEYKATSISASVVGKNDGNWYESFVIGAGKNSGVKK
                     ESIVMNGSGLVGIVYEVSNNYSKAISLLDSKASVSFKLAKDANAKGTITQNTTLDNKD
                     SYNSKGYLQGYMFDSSYNVIQGDIITTSGLGFFPDGIPIGEVEKVVDDKDKSLKYVVV
                     KPYVDFKNINDVVVIEPRNIG"
     gene            complement(8452..9462)
                     /locus_tag="OE968_000719"
     CDS             complement(8452..9462)
                     /locus_tag="OE968_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein"
                     /protein_id="HCP7218034.1"
                     /translation="MTKDMGIDLGTANTLVYIKGQGIVVREPSVVAIRDDSKEVLAVG
                     EEAKKMIGRTPGNIVAIRPMKDGVIADFDITQSMISYFIQKAADKKGVVSPRIAICVP
                     FGVTEVEKRAIEEAARQAGAKDAFLIEEPMAAAIGAGLKVEEPEGNMVVDIGGGTSEI
                     AVISLGGIVTAKSIRIGGDEFDESIVAYVKKEYNLMIGERTAENVKINIGSTFKDDEE
                     INMQIRGRDLISGLPKTIEICSTEVREALKEPVSSIVDAIKSTLERTPPELASDIMEN
                     GIMLTGGGALLRGLDKLITQETGMSVQIAETPLDCVALGTGKSVEDQEIFEKVLMMNT
                     KN"
     gene            complement(9583..10242)
                     /gene="radC"
                     /locus_tag="OE968_000720"
     CDS             complement(9583..10242)
                     /gene="radC"
                     /locus_tag="OE968_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HCP7218035.1"
                     /translation="MAPEERPREKMLAKGVKSLSNAELLAILLRTGNKNKNAIELANY
                     IINRDIQGIRHLEDMTIEELCNIDGIGLSKSTQIKAALELGSRVASFKPIKYKIRNPW
                     DIQRYYMDSLRYLKKEVFKAVLLNTKNEIISDVDVSIGTLSSSLVHPREVFKEAIRRS
                     ASKIIVMHNHPSGSVEPSREDKNITSRLIKCGEIIGIEIIDHIIIGDGLYFSFKENMI
                     I"
     gene            complement(10287..10871)
                     /gene="maf"
                     /locus_tag="OE968_000721"
     CDS             complement(10287..10871)
                     /gene="maf"
                     /locus_tag="OE968_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation inhibitor Maf"
                     /protein_id="HCP7218036.1"
                     /translation="MNIILASASPRRKEILENTNVRFDIIKNEIDEIILEGETPKHLV
                     MRLAFEKSMSVASEHNEDVVIGADTVVVLDNAILGKPKDESCARDMLKRLSGREHQVI
                     TGISLINLCEDKKVIDYVISNVKFKTLSEQDIEDYLKTNESFDKAGAYGIQGYGALLV
                     EEIRGDYFNIVGLPISRLGDLLKKYFSINLFYGV"
     gene            complement(11091..12062)
                     /locus_tag="OE968_000722"
     CDS             complement(11091..12062)
                     /locus_tag="OE968_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RnfABCDGE type electron transport complex
                     subunit B"
                     /protein_id="HCP7218037.1"
                     /translation="MVILTAVLVLGIMGLIFGIVLDFASKKFAVEVDERVEAILGVLP
                     GANCGGCGFPGCGGLANAIVEGNAPVNGCPVGGADVGAKVGEIMGISAEAGEKQVAKV
                     ICKGTCSSAKDKYEYEGISDCRAANVLNSGAKMCKFGCLGLGTCKDACKFDAISIVDG
                     IAVIDEEKCVNCGKCKEVCPKGIIITKPESQEVVVECNSKEFGKAVKEKCTAGCIGCG
                     MCVKACKFDAIIFEDKIAKIDPNKCVGCMQCVAKCPTKVISGDITKKKKVTIDQELCV
                     GCTVCKKQCKFDAIEGELKEKHKVDADKCVGCHLCMEKCPKKAIKIL"
     gene            complement(12078..12653)
                     /gene="rsxA"
                     /locus_tag="OE968_000723"
     CDS             complement(12078..12653)
                     /gene="rsxA"
                     /locus_tag="OE968_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxA"
                     /protein_id="HCP7218038.1"
                     /translation="MNLILLFLSIVLVNNVITSQFLGICPFLGVSKKVDTAVGMGVAV
                     TFVLTLASIITYFIQILLVKTGTGFLQTIAFILVIASIVQFVEMVIQKMSPSLYQALG
                     VYLPLITTNCAVLGIALVNVQKSYNLVETIINGFGAGAGFTLAIVIFAGIRERLELAD
                     IPEAFKGFPITLISAGLMSIAFLGFTGLIKL"
     gene            complement(12668..13261)
                     /locus_tag="OE968_000724"
     CDS             complement(12668..13261)
                     /locus_tag="OE968_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit E"
                     /protein_id="HCP7218039.1"
                     /translation="MNLAKVFKNGLIDENPTFVQVIGMCPTLAVTTSAINGIGMGLST
                     AAVLICANLVISLIRKITPDKIRIPIFIVVIATFVTIVGMLLKAYVPALDKALGIYIP
                     LIVVNCLILARAESFAFKTGAMPSIVDGVGQGLGFTVALTIIGAVRELLGNGSLFGMT
                     LFGASFQPVLIFILPPGAFLTLGFLFAGFNKLRSKKA"
     gene            complement(13274..13843)
                     /locus_tag="OE968_000725"
     CDS             complement(13274..13843)
                     /locus_tag="OE968_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RnfABCDGE type electron transport complex
                     subunit G"
                     /protein_id="HCP7218040.1"
                     /translation="MNSMVRLGGTLLAISAIAALALGATNQVTAPVIEQRNIQANNEL
                     RKAVLPEAKEFKEMKEDTYKGLGDGLIAEVYEGLDGSEVVGYTLKAKPSGYGGEIEVM
                     VGISSEGQVTGVDIGNMSETAGLGAKAKDDAFKGQYKGKTAEPLEVAKGSTTADNQIL
                     AISGATITSTAVTTGVNAAIDVFNSALNK"
     gene            complement(13843..14820)
                     /locus_tag="OE968_000726"
     CDS             complement(13843..14820)
                     /locus_tag="OE968_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RnfABCDGE type electron transport complex
                     subunit D"
                     /protein_id="HCP7218041.1"
                     /translation="MENKLIVSSSPHVRSNEDTSYIMKQVIIALLPAAVAGVYFFRLN
                     ALSAMFFCILGTVGTEFLYQKFTKQKSTIGDFSAVVTGLLLAFNVPASLPWWMCLVGG
                     IFAILVVKMVFGGIGCNFVNPALAARAFLLASFPVAMTAWTQPGVNWIGKNLDAVTTA
                     TPLSFLKNGAAGLADISSNGISLADMMIGNIGGCIGETSAILLLLGGVYLMYKGIINY
                     VIPVFYIATVFILTFLLGGFNITFAIYQLFAGGLMLGGFFMLTDYTTSPMTKKGQIIY
                     AVLAGLITTVIRMYGGYPEGVSYSILLVNCLAPLIDKFVRNRVFGEVAK"
     gene            complement(14843..16180)
                     /gene="rsxC"
                     /locus_tag="OE968_000727"
     CDS             complement(14843..16180)
                     /gene="rsxC"
                     /locus_tag="OE968_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxC"
                     /protein_id="HCP7218042.1"
                     /translation="MKLLTFKGGIHPPYRKEYSNTKALEKAQAPKIVYIPLQQHIGAP
                     AKPIVEVGDEVKFGQKIGEQQGFVSCNVHSSVSGKVIAIEQHEVPGGSAQCVVIENDF
                     KEELHESVQPKGQLEDLSKEDIVGIIKEAGIVGMGGATFPNHVKVSPPPDSKAEVVIL
                     NGAECEPYLTADHRLMVENPEDVVFGLRALMKVLDVKKGFIGIETNKPDAIEAIQNVA
                     KDYSEIEVVGLQVKYPQGAEKQLIYACTGKEVPSGGLPIAAGAVVDNVATAAQIAKSI
                     KTGMPLVERITTITGSCIKEPKNLITKVGTLVSEIIEQCGGFKEDKKIGKVIMGGPMM
                     GIAQYTTEIATNKGSSGILCLDEEESRTPDIQNCLRCGRCTDVCPSFLQPLFISAYSL
                     KDDYDTAEYHRAMDCIECGSCSFICPARRPLLQSIRSAKREIGAKRRKQAAQK"
     gene            complement(16396..17340)
                     /locus_tag="OE968_000728"
     CDS             complement(16396..17340)
                     /locus_tag="OE968_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218043.1"
                     /translation="MNRRKTIYRGFNNNRHKIDLRKYVITIACLCLIGYYSYTKIKDS
                     KILEYVSAKIPFLNNSSDITYKDISDELNSIKKGKKSKSQTNSDDKQETNPEKAVNNT
                     KEPEEVKLATIEGWDMYTIQVAAIDNNDDLKKIQTSLVNNDIPFSVMEKDGVKKIQTY
                     SSFDENDVRKQISSVRKVFPDAFLSHLDAPMLSLEYTSNYAYIESISKELNKLITNFK
                     EESSFWSNAENNVDMEKYNTILTNRKAISQNISKEAEKIDYSEMRLFKDNLIEYVKNV
                     NEKIDTASKAANEEKYSVSKSLLLSSMQEYSMFINSIK"
     gene            complement(17451..18725)
                     /locus_tag="OE968_000729"
     CDS             complement(17451..18725)
                     /locus_tag="OE968_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HCP7218044.1"
                     /translation="MKKAIAALGIGAVAVSVSSINASALEKGTVTASALNIRSGPSSD
                     CDKVAKLYKGKTVEILEKSNGWYKVRVSSSVVGWGSAKYISTSGSSEGTSSQNNPTSS
                     GTTISGNGKVNVSSRLNVRSGAGTNYSLVGKANNGDVVKLLEQSNGWYKIKLSNGVTG
                     WASSQYISKTSEDVGTNNSSNSNSTNNSDKKPSSEESIEGKNGKVTSAVSLNVRSGPG
                     TSYSIIGKLNGGDVVELKAKSNGWYKVKLSSGTIGWVSASYISETNEDTKEKPNSSSN
                     QNSQSNSNSKPSFTGNSDKSTAKGSTIVDFAYTLIGIPYQWGASGPDKFDCSGFTQYV
                     FKHSVGVSIPRVSREQANFGSAISMGNYAPGDLVYFDTDGDGTTNHVGIYVGNSKFIH
                     CSGTQTNPNKVKVDNLTSSYWSKVLLGARRFV"
     gene            complement(18857..19228)
                     /locus_tag="OE968_000730"
     CDS             complement(18857..19228)
                     /locus_tag="OE968_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HCP7218045.1"
                     /translation="MKFNFCHNNFNVTNLEKSLDFYKKALGLKEVKRKEAEDGSFILV
                     YLGDGITSHTLELTWLRDWDRPYNLGDNEFHLALEVEEFDEAKKLHKDLDCICFENES
                     MGIYFIADPDNYWIEILPKNH"
     gene            complement(19456..20055)
                     /locus_tag="OE968_000731"
     CDS             complement(19456..20055)
                     /locus_tag="OE968_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218046.1"
                     /translation="MESRGYKEDLKKMILDMAHKELESYVSQKGAKKYFEGNLDKIIN
                     NNIKKFNQSIGLNRVYLKMLKKCAYQESVTSISRTIKKEALFKSKKELFAFSEYLKLD
                     INKRLSYNQILRKISRYIYYNRSSYAQKYVVFKRGDEEYLLEPEKIKDELISSYRSKT
                     REDMRSIAKLLDIEVEDDYNAEDIRKKVINYIIKEKLKS"
     gene            complement(20256..20468)
                     /locus_tag="OE968_000732"
     CDS             complement(20256..20468)
                     /locus_tag="OE968_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy-metal-associated domain-containing
                     protein"
                     /protein_id="HCP7218047.1"
                     /translation="MKKKLLVEGMSCGHCVNHLKTALTEDIDGIEVLDVDLENKCASV
                     DMKDDVSIEKLKEVIAELGFELKGIE"
     gene            complement(20541..22256)
                     /locus_tag="OE968_000733"
     CDS             complement(20541..22256)
                     /locus_tag="OE968_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HCP7218048.1"
                     /translation="MKRIKVLTVVLAITLMVAGCSNTKTKQSSSDSSLQSQSSIDAKY
                     INLTMVTPKTINPITNTDKSVGYIMNLVYDSLFTIDENYNVIPQLVKEYNIAQDGMSI
                     DIKLKDAKWHDGKNITSNDVNYTIGLIQKSADSPYNEFTKNIASVNIKSDKDFTIKFK
                     ARYAFSIDSLIFPIVSQNHLDSKDVNDKNNNMIGNGKYKIESYTEREGMVLSVNKDYY
                     EEVPKTMKNIKVGMVPNEDARTSMVMALDSDITNVTLNDLSKFQEKEFNITKYQGRDY
                     ECVLFNYNNPFFKDVNFRKAIAHSIDKDRIISEGYMDDATPVNFPLNSKSKYYNSEMK
                     DLEFNKDKAIECLAKVEYANVNSVNQNDNKVKNQKKSAKKNSKKLTPEEEAKAKKAEE
                     DRIKKEAEEKKNREKEEVKKSLSEMNLKIIVNRDNSERIKTANIINENLKAIGINSTV
                     NQLSDKDMENALNSKNYDLALVGWKLSIIPDASSIIASSGYTDDKLNGYMSALTSSTS
                     EIETKKAYKDVQTYIKDNATFISLAVRNNYIVSNSRLKGKITPNDFDVYEGISNLDIK
                     SNESN"
     gene            complement(22256..22810)
                     /locus_tag="OE968_000734"
     CDS             complement(22256..22810)
                     /locus_tag="OE968_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing
                     protein"
                     /protein_id="HCP7218049.1"
                     /translation="MNSKKVLILSIFIILFGALLMESKVIHKFLYPKKYSEYVEKYSK
                     EFNLDENIVYSVIKAESKFNSSAVSKKEAKGLMQILDITRDWGAEELNLKNVDIFDPE
                     TNIRLGCWYLSKLYKEFGKLDLVIAAYNGGSGNVKKWLENNEYSKDGENLHDIPFKQT
                     SKYVEKVKNNYEHYNKIYGKKGKN"
     gene            complement(22803..23405)
                     /locus_tag="OE968_000735"
     CDS             complement(22803..23405)
                     /locus_tag="OE968_000735"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HCP7218050.1"
                     /translation="MLILGLTGGIGCGKSSLSNIFRNLNIPIVDADIISRKIFEDKLL
                     LEKVFVHFGQSIKNDDGTLNRKALGKIVFSDEEKLKELNNLTHPRIREKIISEIEKLR
                     KKGENIVVLDAAILVESGFLDMVDKLLVVTCKQEVQISRIQKRDNCSEQEALSRINSQ
                     MSQEEKSKYGDYIIDNSGTITELESKAHKFIEYMKENWRE"
     gene            complement(23414..26062)
                     /gene="polA"
                     /locus_tag="OE968_000736"
     CDS             complement(23414..26062)
                     /gene="polA"
                     /locus_tag="OE968_000736"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HCP7218051.1"
                     /translation="MEKKLIIIDGNSIINRAFYALPEMNNKEGLKTNAIYGFTTMLFK
                     MIDIYKPTHISVAFDRKAPTFRHLEYKDYKAGRKGMPDELAEQLQPLKDLLDKFRINR
                     LEIDGYEADDIIGTVSKKAEENGYKVYIVTGDKDAIQLASDNTTTLITKKGVGEVEEY
                     NFNSVIEKYEMTPTQFIDLKGLMGDKSDNIPGVPGIGEKTGIKLIKEFSSIENLIENT
                     DKLKGSVKKKIEENKEIAIQSKRLATIIRDVPIEVDLDSMIFGDYDKDELLDKFRYFG
                     FTSLLSRLVDLVDSDDTEHVEEKIEILKLKDIEKFIDEVNKKGQVILKTVRGQGNILE
                     KNIIYIFISVDGEKIYYVDSNEVSKLDSIFSNNEIKKYGYNLKDDYISLKPYNINLEN
                     MYFDITIAEYLIDSTSSTSYDCSAIAMKYLSKKVKSKEELLGKGVKSKNYEDLEFEDL
                     AEYMGQIICTVKETVPMMERSLMDMSMDGLFYHVEMPLVEVLGHMEYEGIKVDKSILD
                     ELSVEFKEIIATLEKEIYELSGEPFNINSPKQLGVILFEKLELPIIKKTKTGYSTNAD
                     VLEKLRDKHPIIDKITEYRQIVKLNSTYVEGLLNIINPESNRIHSSFNQTITTTGRIS
                     STEPNLQNIPIKMEMGRKIRKVFIADDNCKLVDADYSQVELRVLAHMSQDENMIEAFK
                     HHEDIHTKTASQVFNVPMEDVTSELRGAAKAVNFGIIYGKSDFGLADDLNIPVPKAKE
                     YIESYFAKYHKIKEFMDTTVEKASEDGYAVTILNRRRYIPEIKSSNFMERNRGKRFAM
                     NAPIQGSAADIIKIAMINVHKKLEENNLKSKLILQVHDELIVEAIDDEIDIVKKIVKE
                     EMENAVNMDVHLDVDLNVGSSWYETK"
     gene            26214..26301
                     /locus_tag="OE968_000737"
     tRNA            26214..26301
                     /locus_tag="OE968_000737"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:26248..26250,aa:Leu,seq:caa)
     gene            complement(26488..26931)
                     /locus_tag="OE968_000738"
     CDS             complement(26488..26931)
                     /locus_tag="OE968_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218052.1"
                     /translation="MKKNMLYVGIIYFICGILLVLLATFTEFSFEAFIWGLSGAALGP
                     GVCMILQYMYWSKPERAVDYEEKIKNQRIEMNDERRIMLRDKAGRITNQIMCYVLVIL
                     IFIVSILSVFSVMVISKWVLVVLGLLILFQFICSVVVYNKLDKRL"
     gene            complement(26934..27131)
                     /locus_tag="OE968_000739"
     CDS             complement(26934..27131)
                     /locus_tag="OE968_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004631111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCP7218053.1"
                     /translation="MKNRLEEIRKERGIKQEELASILQVSRQTIGSLENGRYNPSIIL
                     AFKIARYFDMSIEEIFIYEEE"
     gene            complement(27323..28189)
                     /locus_tag="OE968_000740"
     CDS             complement(27323..28189)
                     /locus_tag="OE968_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HCP7218054.1"
                     /translation="MEWINKLNQAITYIEENLESGVDYAEAAKIACCSTFHFQRMFSY
                     IAEVPLSEYIRRRRMTKAAFELQNSNIKILELSEKYGYDSPTSFNRAFQNIHNISPSA
                     ARAKGVVLKAYPKMTLSIYVKGNIEMQYRIVEKKGFRIVGIKESMNMIVEECFEKVPK
                     LWAKCIKNGTIDKLSELINNEPCGLLGVSVCTNSKGLDYYIAAPTDKPVLEDTHEYLI
                     PSGTWAVFECVSPMPNALAIQELQKRIITEWLPSSGYVYANLPDIELYPNGDINAPDY
                     TTEVWIPIQKPS"
     gene            complement(28415..29284)
                     /locus_tag="OE968_000741"
     CDS             complement(28415..29284)
                     /locus_tag="OE968_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HCP7218055.1"
                     /translation="MDYKTIILNRKSVREYKNTDIKEEYLSEIKKYSESCKKLVPEID
                     VDVRIMNRSEVFNNLDKVAGYKGNMIDSPSYIIILSDIKDNYIENSGYIGESIIFKVT
                     ELGIGSCWVTFEDGKKVKEKLGINSDKEVTGIIAIGYGENVSNAKVLNATKTGQNYSK
                     SDMQVVTDKGSTRLGVEDVVYMNEWGNVASIEILEERALLDAFHYARLAPSTLNRQPW
                     RFIVDGGTVVLAVRKDGHTNLYEEKIDIGIVMLYFATIISATMFDLKWNLGTPDKDYK
                     VPEDYKIVGYCNI"
     gene            complement(29790..30011)
                     /locus_tag="OE968_000742"
     CDS             complement(29790..30011)
                     /locus_tag="OE968_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218056.1"
                     /translation="MNVNNHKCPECGEHSKKFEIVEENEDCVIFECYTCGTISILKYC
                     ENCKEFVFVNIPNNVETYEYCCGKCNNKI"
     gene            complement(30513..31493)
                     /locus_tag="OE968_000743"
     CDS             complement(30513..31493)
                     /locus_tag="OE968_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218057.1"
                     /translation="MGDTSRFYESVKNKYPKLKDGTRVHLWPKENIIIGPIYDEEDGY
                     KKSIGNVDSLSWKQIVILAECDGKNTTDDIINILSNRYRNIHNMKEKVMEFFMFYENV
                     YLTFEDDIQTLSSVFEITGNKSYITPLYFTIEIDGDNNTNDYFSEITSLLNCMYEKGC
                     RFIEVIGEDILKNKSMREIFQYMLDHFDLIVVTKDSFTIDRSLIKELDNYRHKVIWKV
                     YSKNDDTRIKLKEDIKITSLIKRGHTVVRGDREKAIKIEDMRFKDTKERFSKYGAEWS
                     HLYISSDGSVKSYSFQKDKRIYLGNIFNNSVEEIFLEMQNKIDKLEIVYQ"
     gene            complement(31657..32529)
                     /locus_tag="OE968_000744"
     CDS             complement(31657..32529)
                     /locus_tag="OE968_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HCP7218058.1"
                     /translation="MIIKVSMTVLVLILLYILYKYETQHIETTEYTIFNKKIPKEFDN
                     FKIVQVSDLHNKVFDKNNKVLIDKIESLNPDVIFITGDLVDGENKNFQVALDLIDNLV
                     EKYEVYHIIGNHEQKSLIKKYKHLYKDYFKELYSKKIINMENESVRIYRGNSHLNLYG
                     LIIPLECYPYLFANNKKLELSDNFVEDNLGKVNENEYNILLAHTPFFFEKYAKWGADL
                     VLAGHVHGGIIRIPFVGGVLSPNREFFPKYDWGKYEKDNSTMILNKGLGGSKVLIRLN
                     CKPEIVKITFKYEK"
     gene            complement(32693..33244)
                     /locus_tag="OE968_000745"
     CDS             complement(32693..33244)
                     /locus_tag="OE968_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCP7218059.1"
                     /translation="MDNKFPNVGENLRLLRQEMGISLDKASKMTGVSKAMLGQIERGE
                     SSPTVSTLWKISSGFKINFTTLLNENTNTYEVIKKEEVEPIVEQKGNMKLYPIYPFSP
                     QRRFELFIIELEENCTHVSSTHSHVLEEYVLVIEGKLDLNVDGKTYILESGHSIRFDG
                     TLEHIYKNLNKGKTIFHNIEVYR"
     gene            complement(33264..34166)
                     /locus_tag="OE968_000746"
     CDS             complement(33264..34166)
                     /locus_tag="OE968_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HCP7218060.1"
                     /translation="MSKKGRVVKVQHFSVNDGDGIRTTIFLEGCKLKCKWCSNPDSWS
                     NIVKLGVMKDKCVSCNRCIDVCPQNISSLFDRAQINNKCDLCGECIKVCLKDAICIMT
                     EEMSVEEIVEEVEKDFIFFFESNGGITFSGGEPTLQIDFLRELVDIFYDKGINIAIET
                     CGYFDWNKVNDVFEKIDHIFVDIKSMDDNIHKEYTGVSNKIILDNICRLSKLNKSMVI
                     RVPIIYGVNDSEENIRNTALFVKQNVPGGKMELLPYHKFGIDKYKALGLEDYIYEFDD
                     ICNNHMLKLKEIVELTGVKIIEYK"
     gene            complement(34181..36553)
                     /locus_tag="OE968_000747"
     CDS             complement(34181..36553)
                     /locus_tag="OE968_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase/glycerol dehydratase
                     family glycyl radical enzyme"
                     /protein_id="HCP7218061.1"
                     /translation="MSQTNRIEAFRQEYINSKPMICCERARIFTESHKKTEGEAICIR
                     RAKAFLETCKELPIKIFENELIVGTAGKFRRTGILTPEFSWQWVDKEMDTFDKRTQDP
                     YVISKEQIEFIRKEIFPYWKGKSLEEVFLARIPEDTAKILVDTGIIDNDSKWRQAVGE
                     VTPDYQDILFVKGYKGIKEDADKKIKELDISVSENIEKIDFYKSVSIVAQGIMTLAQR
                     YSNLAKEMSKQETDEKRKLELIKISEICMNVPANPPTNFYEAIQFVWFVQLGGILSEN
                     PLALNLGRFDQYMYPYYENDAREGKITESEAQELIEALWIKLSEWVWTISANTANYFA
                     GYNQFQNLTVGGKKRNGTDGTNDISYMCLKATESVKTHQPGLSVRVSQGAPDNFVMAV
                     AKLVKQGTGFPAIHSDSAGAQMLLQDGYDAEDARDWSNCGCVVPHFRKTGQWTSAVNI
                     NFAAALEYAMNEGKSRLTGEKMGLDTKNITEFTSFEELKDEFLKQLAYLVKSSVIGTT
                     VAQQIHKEMVPRPFLSTCVDGCLDKGVDLSKGGAKYNIGPVLTGIGLGVVSNSLAAIK
                     KLVFEDKVTTLEELTKALNNDWEGYEELRKLALDVPKYGNDNDYVDSLAIEVSDFYYT
                     ETRKYKDIFGSKFNSAFMGISNYVPTGKIVGATPCGRKATKPLTEGVSPFVGTDTTSP
                     LAAMKSASKINHDVHTGGTLLNLRLNQDLVETERGLRNLTSMIKSYFALGGFHVQFNT
                     ISNDTLLKAQENPEEYKDLLVRVAGYSTQFVNLSREMQDAIIARNSHSNF"
     gene            complement(36774..37463)
                     /locus_tag="OE968_000748"
     CDS             complement(36774..37463)
                     /locus_tag="OE968_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218062.1"
                     /translation="MKVKRNINRVAIIVALNLSLALMVGCMSPVYDKNLSSSEQISKD
                     SLKEQVEDKKDESIELFNNYSQKINDAKGREEVKKDLSQRFSKAIIDSGYSITDSKSD
                     GSFVVSINGAEKPPEKNIRSLFYSMSEDDKEGKVTIDILCAKEYPEDDKLSESDKYIK
                     FIYNLFKSLTNTNLTEKEIFSMVEEDFNKGVGVVELPYMKDIHVEVNKVKQSTKVLKL
                     SLVYKFDISNH"
     gene            complement(37704..39083)
                     /locus_tag="OE968_000749"
     CDS             complement(37704..39083)
                     /locus_tag="OE968_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HCP7218063.1"
                     /translation="MLNFMTELLVVLSIFIQFSIMNGILIYKKDSKKNEKIVFYIVLF
                     LIYIIIQISRLFNGGNYFSNINYLFYILAFIAWGGYYNYFYKMGYIKYSIFFYLFSVY
                     YKCLDAVIYRILFFAITGNVISSKESLLVPHLESIKIQIYSNLIIILIYLIFSFFRKS
                     IKLISQDKRNYVYLLFALLVNTMNMLVNYVLKKLERFGSLHSEGYYFDNFVNPKLVGA
                     SSIFLILLFKEIIKENRLKSQAELIKNKLDMQYAHYLSIQESHMRVKKLYHDINNHIY
                     CIDNLRNNSKEINEYVNNLKDEIKTFKYIYNTGNMILDIIINEKSEICLKKGIKFTCS
                     INFSKVNFVKPIDVSSIFSNILDNAIEACDKIVDENVNKYIRIKGTMTRSFFVLKCEN
                     SKLNQLTFNKNILLTNKMDKFVHGIGIQSIKSSLQKYNGELLFENSIDKFILNIYIPL
                     DQDTDSWGD"
     gene            complement(39077..39790)
                     /gene="rgbR"
                     /locus_tag="OE968_000750"
     CDS             complement(39077..39790)
                     /gene="rgbR"
                     /locus_tag="OE968_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RgbR"
                     /protein_id="HCP7218064.1"
                     /translation="MIKIAVCEDEKETQLLIEDYLENILKDISIEYEIQKYISGEELL
                     ESNLKDIDILLLDIKMEKLNGMDTARKIREVDNEMEIIFVTSLIDYVQEGYEVRAYRY
                     LLKPIELEELKKHVLTCIKDIEINKESHITIKNKSNTYKIYLNEIKYIEVQKKDMLIH
                     TINKNFDIKYSLGKIEKELNPYKFIRCHKSFIVNLRYVENIKPNTAILESGEEVPISR
                     YRYKEVKEKFLKFLGDTIC"
     gene            complement(40040..40600)
                     /locus_tag="OE968_000751"
     CDS             complement(40040..40600)
                     /locus_tag="OE968_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HCP7218065.1"
                     /translation="MSAMEKKIKFKFDWYSSPDKIEKWLEDIEAKGYNLYKINKFGGI
                     FYFHKGSPRKIKYTVDYYYDVENNYFDEHKSNGWNLVFRSIGSFMGTSAWYIWSKEYK
                     DIPPKLYSDSDKKNKVKSILFMNMFIFFMLVVIFIYLLNIEIRNLYSGYGASVTAIVL
                     QIILLILYAVQLYRRLMYYLRLKKFK"
     gene            complement(40696..41499)
                     /gene="zupT"
                     /locus_tag="OE968_000752"
     CDS             complement(40696..41499)
                     /gene="zupT"
                     /locus_tag="OE968_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc transporter ZupT"
                     /protein_id="HCP7218066.1"
                     /translation="MNNVIFAFLITLLAGLSTGIGSCIAFFAKKTNTKFLSISLGFSA
                     GVMIYVSMIEIFPKAQDALTKSMGEKLGSWSTVIAFFIGMAIIAVIDKLIPQEENPHE
                     IKKMENIEEKNIKKNKSLLRTGIFTAMAIAIHNFPEGLATFISALDDVTIAIPIAIAI
                     AIHNIPEGISVSVPVYYATGDKKKAFYYSFLSGMSEPLGAIIGYVLLRNFLNDITLGI
                     VFAIVGGIMVFISLDELLPSAREYGEHHLSIYGLIAGMGVMAISLLLFK"
     gene            complement(41650..42813)
                     /locus_tag="OE968_000753"
     CDS             complement(41650..42813)
                     /locus_tag="OE968_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HCP7218067.1"
                     /translation="MDIKEITKSYKDYVIKLRREFHENPEKSMEEVRTSKRVKEELDK
                     IGIPYVSAGGTGVIATIKGANPGKTVALRGDMDALQVVECTDVEYKSKNEGLMHACGH
                     DGHTSMLLGAAKVLNDIKDSINGTVKLFFQPGEEVGKGARAMIQDGAMEGVDSVFGIH
                     LWTDVESGTISVEEGPRMASADFFKITVKGRGGHGSLPHQGVDAVLASSAIVMNLQSM
                     VSREVSPLEPLVVSVGVLNSGTRFNVIASEAVLEGTIRLFNPELRKQIPGILERIAKS
                     TAEAYRADAELEYGYLTPAVINDKECSKIATDAAIKLFGEDCITLFEKVTGAEDLAEF
                     MNIAPGALAFVGARNESKGACYPHHHGCFNIDEDALEIGTALYVQYAVDFLNK"
     gene            complement(42873..44060)
                     /locus_tag="OE968_000754"
     CDS             complement(42873..44060)
                     /locus_tag="OE968_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218068.1"
                     /translation="MEAITAFCLVLVSLTIGDIVSAKTKAFVPSVFVSAIIFIVGFWT
                     FFPENIVDLAALGTPLAQLGMLLLITHMGTMMSIKELAGQWKTIVIALAGIVGICVGA
                     LALGTVVFGWDTAVIATPPLTGGLVASIMMADAATAKGLASLSVLAILMYVAQGFAGY
                     PITALMLKKEGKRLLSDFRSGKVTVNTDEEKVKDLPEQKSRFKIIPDLPEKYDTTYMI
                     ILRLGFVAWLAVQFTNLTNEVVSRYVICLIFGVIASELGIVDRKPLNKSGSFGWLMTS
                     LMAFIFAGLAKATPAMLVEMAVPLVGIIIFGVIGMGIFSIIVGKLLGESKEMAFSVSL
                     TSLYGFPPNYILTEEAVKALAETPEEKEFLMDKMLPKMLVGGFTTVTIASVVIAGIFV
                     NLI"
     gene            complement(44423..46123)
                     /locus_tag="OE968_000755"
     CDS             complement(44423..46123)
                     /locus_tag="OE968_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCP7218069.1"
                     /translation="MIKQFVKYYKPYKKIFTLDLIAAFLFSLCDLVYPMITRNIMDDV
                     VPNKNLRMLVVFAVALILIFIAKAGLNYFMQYWGHVIGVDMQADMRNEVFTHLQRLPN
                     TYFDNNKSGVTMSRIVNDLMDITELAHHGPEDLFISIVMLVGSFFILIDINIPLTLII
                     FAILPFIIWFAIAKKDKMNIAFMKSRVTIGDVNATLENSIAGMKVTKSFCTEKEELNK
                     FVRSNKLFRRARQDSYKVMAEYYSGMNLYMDILEWVVVIAGGYFTYIGKITLGDFAAY
                     ILYVKMFIQPMKKLINFTEQYQNGMTGFKRFIEIMEQDHQKEAKNPIELENVKGDIEI
                     ENISFTYEDKTQVLDNLSLSIKAGKTIALVGPSGGGKTTLCNLLPRFYEFDKGDIKID
                     GKSIKDVSLKSLRKNIGIVQQDVFLFTGTIRDNILCGNPNATDEEMIAAAKKARIHDF
                     VETLPDGYDTYIGERGVKLSGGQKQRISISRIFLKNPPIIILDEATSALDNVTEREIQ
                     ESLEELSKDRTNLVVAHRLTTIKNADEIIVLTDKGIEERGTHEELVNKNGVYSRLHNN
                     "
     gene            complement(46378..46653)
                     /locus_tag="OE968_000756"
     CDS             complement(46378..46653)
                     /locus_tag="OE968_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCP7218070.1"
                     /translation="MKKILVACGAGIATSTIVCDRVERLVKENNIQAEVEQCKIAECS
                     TKQEGADLIVSTTILPTTYDIPTIKATGYITGINTTALDKKILNALK"
     gene            complement(46772..47344)
                     /gene="mobB"
                     /locus_tag="OE968_000757"
     CDS             complement(46772..47344)
                     /gene="mobB"
                     /locus_tag="OE968_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-guanine dinucleotide biosynthesis
                     protein B"
                     /protein_id="HCP7218071.1"
                     /translation="MLLLDSFMKGHNFMYNILSVVSYSGVGKTTLIEGIIKELNKKGY
                     RVGVIKHTCHDFDMDEEGKDTYKHRKSGARKVCIISDKRVAYIEELKEKNPLYKMIQL
                     YEDMDLIIIEGYKNYRFKRLEVTRKGKYEDILSNKSDLIGIVSDIEYKLNIEQFNLND
                     YKNISKYIESCIKNEILSISNVEIKNILKE"
     gene            complement(47328..48509)
                     /locus_tag="OE968_000758"
     CDS             complement(47328..48509)
                     /locus_tag="OE968_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin molybdotransferase MoeA"
                     /protein_id="HCP7218072.1"
                     /translation="MIELEDAIKIIEKNVLPINRVKIVNLIDAVNKVVAEDIYSTIDS
                     PPFDRSPYDGYAYNANSENRNLKVIGTLYAGDVFNRVLNKNEAVKIMTGGKIPQGANC
                     VIKKEDVTVIGDMITLNIKLKEYDNYIFKGEDIKKGQLIINKNQNIGYDGIGVLASLG
                     ISKVTVYDDLKVGILNTGTELQDINETLENGKIYDSNRYTLYSRLLKLGIQADTICNC
                     SDDILELEKKVKNMLQSVDFLITTGGVSVGDKDLIPDVFKKIGATELFWKINIKPGGA
                     CYVGTLGEKLLFGLSGNPHAAIVVFDNVIVPVIEYLTYKKGTHHIKAIFKGEFNKFSN
                     KDRFVSGKLYTSEGKLYVELNDKKDAKARLSATLRSNCMIKIKKNETIKENQLVDVVI
                     R"
     gene            complement(48720..49454)
                     /locus_tag="OE968_000759"
     CDS             complement(48720..49454)
                     /locus_tag="OE968_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218073.1"
                     /translation="MKLKRSLVCVTILGIILVGCHKENTKEKNQVASKATQQKTMTKV
                     QNDVNEIMNKDYKYIIKNMGIPYNTFYYIKPKVLKESNTMQDINTSSYMTLVYPKYTG
                     NDELDGSALYVDINENKVVNVETNSFSSQGISVIDAESSIVIEKSDHEKSAVSLENFR
                     HIDLGEYVGVEDSRINEIVGDANYDLTAYNHEGSKVVKSYRLKEDNKILKKEVLTISI
                     VDNKIKSIKTIESDKIVKIIKGTLLE"
     gene            49816..50721
                     /locus_tag="OE968_000760"
     CDS             49816..50721
                     /locus_tag="OE968_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCP7218074.1"
                     /translation="MDFKQLEVFVAVAKHQSFSKAARELFLTQPTVSAHIQNLERELE
                     TVLINRSNKVITLTKSGEILYEHAIYILNNCKRAIYDIKEYSGKIEGIIDIACSSIPE
                     TYILPDFMKSFSMSYPDVKFSISHYDSQYAISEILNERISFGLVGSKINNPQIEYLDL
                     LDDELVLITPSDFKIDNKNNCIDIGELAYLNFIMRKEGSGTRNLILNTLSKNNFPVSK
                     LNVIAHVESNEAIKEMVRLGLGVSFISYISAIDYLNAGKIKCYKIKDVDFTRKFFFIY
                     SKKKTFSPLEDKFLNRLCEYFEIII"
     gene            complement(50881..51723)
                     /locus_tag="OE968_000761"
     CDS             complement(50881..51723)
                     /locus_tag="OE968_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HCP7218075.1"
                     /translation="MTTSSKKLETISPDSKITRKDFWKCFRRSLTLDSSWNYERMQNI
                     AYAYMMAPIIRRLYKDDKEKKSKALKRHLEFMSVTPHISTLLVGISGAMEEENAKNKE
                     FDANSINAVKSSLMGPVSGIGDSFFWGTLKLIAAGVGIALASQGNIMGPILFLLIINV
                     PHFIIRYICLDKGFKYGTQFFKDVSGSSIVSKVMEAASMLGLMVIGGMTASNVMLKLS
                     VNVGSGEWAEPIQTYLDQIMPCMLPAMIFGIMYWLLGKKVKTTTILISVMIICIVLAA
                     IGVV"
     gene            complement(51707..52465)
                     /locus_tag="OE968_000762"
     CDS             complement(51707..52465)
                     /locus_tag="OE968_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCP7218076.1"
                     /translation="MEFTQVILITLIAFFAYMHSFVGSTMHNRPIVVAPLVGLALGNL
                     HTGIVIGSTLELVFMGAFPVGASNPPDFVSGSIIATAFVILTGQDVSAAVVLAVPIAT
                     LVLLIDNFLMTVVLTWGAHIADRYAEEGNIEGVERVQLLFGIGNKLILAIIVGIGFSL
                     GVPVIEKILSFIPSYVTHGMDVAAGVIPAIGFAMLARMMLNKKTVAFLLLGFILVAYL
                     NITVTGVALFGLAIALIYVNFVGEKEVIVDDNEF"
     gene            complement(52482..52952)
                     /locus_tag="OE968_000763"
     CDS             complement(52482..52952)
                     /locus_tag="OE968_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCP7218077.1"
                     /translation="MIKLVRVDHRLIHGQVAFTWTKFLSTDCILIASDDLLKDELRMA
                     GLKMAKPSNVKLVMKSIADSIKALNSGVTDKYNLLILCESVEDVYRLAKEVKAIKSIN
                     LGGTKSDDNRENISKAVHVSKDDIKMIKELDSEGVNVFVQLVPDDDATNVMKLI"
     gene            complement(52952..53695)
                     /locus_tag="OE968_000764"
     CDS             complement(52952..53695)
                     /locus_tag="OE968_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane biogenesis protein"
                     /protein_id="HCP7218078.1"
                     /translation="MKKKGILSVFKSKKPIIAMIHLKGDTPEDIFERAKKEITIFEEN
                     GVDGIMLENYYGNYYDLERILEYVSKANLSIPYGVNCLNVDTMGFELATKYNASYIQV
                     DSVVGHVKPRDEATLEEFFKLQRSKCPAYLIGGVRFKYQPVLSENDVEEDLKIGMTRC
                     DAIAVTENATGQETSMEKIELFRKNLGDFPLVIAAGVTLENAKKQLKLGDMAIIGSYF
                     KDNYKDFGDVSVEHVKTFMDEIKKIREEL"
     gene            complement(53699..54112)
                     /locus_tag="OE968_000765"
     CDS             complement(53699..54112)
                     /locus_tag="OE968_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HCP7218079.1"
                     /translation="MKKIILASHGDFSKGLLNAVKMIVGDLADCVSSYGLYPGQSASD
                     FALELEKTISEDKECEYIILSDLYGASVCTAMLRLTNLHNVRLFSGMNLNMVLELLTR
                     FSDELTVEDIDQLVEESRRGIQSVTLQIKEEEEVF"
     gene            complement(54138..54722)
                     /locus_tag="OE968_000766"
                     /pseudo
     CDS             complement(54138..54722)
                     /locus_tag="OE968_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896033.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
     gene            complement(54907..55290)
                     /locus_tag="OE968_000767"
     CDS             complement(54907..55290)
                     /locus_tag="OE968_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HCP7218080.1"
                     /translation="MKISKLPEAELKVMRYIWEANDVLTSKELVAAMEEKYEWNESTT
                     FTVLKRLERREFLSTEKIGKLTHYNAMVKEKKYLRFETKEFLKNIHKNSISSLISALH
                     SKDDEVDEDKLIELEEHFKNLKEKE"
     gene            complement(55400..55777)
                     /locus_tag="OE968_000768"
     CDS             complement(55400..55777)
                     /locus_tag="OE968_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HCP7218081.1"
                     /translation="MKEEILVEKLLRAELIVMEYLWKKDSLVTKKEIVKEMRQVYRWH
                     KSTIKILLKRLVDKGYLARDIIKFQSHYKIIIDNKEYYAFKKKVLKSSKSRKIMRSLT
                     TTHKSISKEKLDALEEYYRNLEE"
BASE COUNT        17643 a        10349 c         5794 g        22148 t
ORIGIN      
        1 tgtaccaccg ccttttcacc tactactcta taatgtatag tacttatatt tactataata
       61 ttacatagta ctctatattg caaggtttat attctacaat agacttaaaa ataataaata
      121 gctgtatatt aatatttaat ctataaatac taatatacag ctatttatca aattttaaaa
      181 ataaattttt gttttattaa tgttgtcata acaacattta cttggttgaa atagtattac
      241 ctataagttt aaatatatat aataatagac ttgattctat ttcatattat taaaatagag
      301 taatagttta aattctacta ctctatctat aatctatttc ctaattattt aatctcaaat
      361 ttagctcttc atcatttaaa tctttcataa gatttctaca ggtactagat ttattccaac
      421 agaaagacta gggcattaaa cacttatata tctgtttctt tagactgtaa tattaatatt
      481 ttttaaatac gttgactttt gctttttcta acttctctcc atgatagttc tcctctatca
      541 agagctttta taaatatttc tgctgaagct agatttgtag ctattggaac atgataaaca
      601 tcacaaagtc ttattaacgc ttgtatatct gtttcatgag cctgagatgt caatgggtct
      661 cttaaaaaaa taactaaatc tatttcttgt gttactatta aagaacctat ttgttggtct
      721 ccacctaaag gaccagatgc taatctattt atatttaatt cagtttcatc cattattctt
      781 tttcctgtag ttccagttgc atatagtcca tactttttta aaattgattc ataacctata
      841 caaaatccga ccatagtgtt tttcatttgg tcatgtgcta ctaatgctat attcatatat
      901 ctaatctcct caatttatgt ttagatgtat ttaaatttag aaatttattt tctttcttct
      961 catacacaca tttagtacta atcctaagtt tgctaaagat gtcaataacg aacttcctcc
     1021 ataacttaca aaaggtaatg ttactccagt tactggtatt aacgcaaccg tcatacctat
     1081 attttggatt atctggtaac caaacattcc cataacacca accactatga gggttccata
     1141 aaaatctttt gcatctcttg caattgctaa aagccttaat aggaatatca taaataagat
     1201 tatcaacact gccattccta ttacaccaag ttcttcacct acaacagcaa atataaaatc
     1261 actatcttgt acaggtaaaa aatcttcttg attttgactt ccattgtaaa gtcctttacc
     1321 agttacgcct ccagaaccaa ttgcaatcag agattgcata acttgatagt ttccttttag
     1381 agttacatct tctggattta gaaaagcttc tattcttacc ttttgatggt ctgccatcat
     1441 taaatacatc agtggcattg acactaatag tatgattatt cctcttttta tcaactttga
     1501 gctaagacct gctgtgaaca gcattgcaaa tatcatacaa caaaatacaa ttcctgttcc
     1561 caagtctggt tgtgcaatca ataatccgat aaatggaaga gaataaacta caacaggcat
     1621 aacttccttt aacgtattta atttatcctt tttggattca agtatctttg cataacttag
     1681 tacaaatgtt aatttgacta tttcagatgt ctgcaagtca agtggtccta agttaatcca
     1741 cgacctagct ccacctttta ctgtcccaat tccaggtaat aaaactatgg ctaacaaaat
     1801 aagacttatt atataaagcg ctttataata cctgcctaga aggttatagt caaaaaataa
     1861 tatgactata atcattccta tcccaagtac aaaagctaat ccttgtttaa tcaattgatt
     1921 atatgaacct gttgaattag catgtgttgc actactaagt ataacaagcc caaaaataaa
     1981 gatagctaat actgtaacta taagtttcca gtctaactgt tttatcaact taattgtcga
     2041 cttataatta atattgattt ttttcaaaga atcaccgtct ttctatcttt aaacatataa
     2101 ttaaataaaa ggggcatata ccaataagga tatccccctt ttaagcacta attacataca
     2161 tctatctttt atattcttta gtggtatatt agcaactaat gcagatacag gtttgtcatc
     2221 atgctcacct ctgcatttag acatttttat ttcaagacca tcatcttcta tttctgcata
     2281 attagctatt acttttaaaa tgtctgtttt tatcatctct aaaagttgtg gtgaacaatc
     2341 tactctatca tgaactaaaa ctagctttaa cctctcttta gcaacagatt tactagtttt
     2401 agcctcgtta gaaaaaactc taaataaatc taacacagat gtatcctcct ttgctactta
     2461 gccatgctaa acattttttt aagtctacca aagaatccat cttcaacttc aagatcaagt
     2521 agaggaactt cttcatttag tatccttttt gcgatatttt tgtatgcttg accagcaagt
     2581 gacttagaat caagtatagc tggctctcct ttatttgttg atataattat gctttcatca
     2641 tcaggaacaa gacctaacaa atctattgct aatatttcta ttatatcttg tttatccatc
     2701 atgtctccac gcttaaccat atcatttcta attctattta taactaatct tatctctttt
     2761 atttcatttg cttctaatag acctattatt ctatcagcat ctcttactgc tgatatttct
     2821 ggattagtaa ctacaatagc tctatctgcc ccagctactg catttttaaa gccttgctca
     2881 atacctgctg gacaatctat tattatatac tcgaaagatt cttttagttt ctcacacagg
     2941 tcaatcatct gctcaactga gacagcattt ttatctctag tttgtgctgc tggtaataaa
     3001 tatagattat caaatctttt gtcttttatt agagcttgct taagcctaca agttccttca
     3061 actacatcta ctatgtcata aactattcga ttttcaagac ccattactac atctaagttt
     3121 ctaagtccaa tatctgcatc cacaactact gtttttttat tttctaggct tagcgcagtt
     3181 cctaagtttg ctgcggtagt agtttttcca accccacctt taccagatgt tataactata
     3241 acttcgctca taatactacc ccctattttt ctttctattt gtctaacttt gacaaatagc
     3301 tttcgattac aattcttcca ttacttacaa aggctatttc tgggctaatt tctgattcac
     3361 tttcataatt ttcttcatca tctggagctt ctgcaatatt atctgctatt tgtaatattt
     3421 taggattaag atttccagca acaacatatg caaattcatt gccttctgca cctgcatgta
     3481 caaaaccttc tattttaccc attacaaaaa cattacctcc tgctacaacc ttagcaccag
     3541 catttatatc tcccataaca actgtatttg attttgaaag gacttttgaa ccaggtttca
     3601 tatcattcaa tataactaca tcaccttcaa attcaatatt ttcaccagat cttagggtat
     3661 tgacatattt tgttggaaaa ttactatttt cttcaatttt ttgatcttca acaaattcca
     3721 catcaaatct agaagtaatt ccttctttaa gttctagaat ctccatgtca gttaaacaat
     3781 cactattaat tttactaatt ttagccccat taaaaaagcc aacatatgct tccaatttgt
     3841 ttattatttt ttcctgtatt tcctcaaatg gagcttctct ttttatattt actattatcc
     3901 ctcttttatt acccttgaac tctactagtt cttgactaca aatttctctt aaagacataa
     3961 caacctccag agtgatatat catttatatt cttcaaatac gctttaaacc cttttatttt
     4021 ttctatataa agctaaagtt tatacataga ttgagctatc tattaatttg tgactcgaaa
     4081 tttatatttt cgtcagaaga attgttaaca tcattcgtct tgttgtcatt tttactatta
     4141 gttggctcta atcccatata agttccaata acttctctag ttggtaaaag tgagaataca
     4201 cttgaatcac cttgaggaat tacacataca acagctattt ctgggtcatc tgctggagca
     4261 aaagcaacag tccacgtaaa agaaccataa tcttgtttaa atctatctat ttggtcatct
     4321 gttatttttg gatttaattc ttttatagct tttcttagat atgaagaatt caccttatca
     4381 gtgtcctcta atctaacttt tactccatct tctaattctt cctctaattt ctttctttct
     4441 tcgtctttca aatctttatt ttctaatttc ttttttattt ccttttcctt agctaatgaa
     4501 agctcttttt ctttttctgc tttcatctta tcagctagtt taatcgcatc atttaggttg
     4561 acattataag atgacatatg actttttaaa tattcatact cgttatctgt aggtattttc
     4621 ccacttttct cagctgtacc agtttttgct gctacatcta ttggaaaatc agcaaaagca
     4681 ctcttcgctg taccttgtct tgcaaccaat ttcatacctt ttgttaattc ttttaagtta
     4741 tctggatttt taaaaggtat tttttcgact ttcttctggt cattaatttt aactgatgaa
     4801 taatcacttg aaacagctct atcaactaca gataattcta ctaaattacc tccatttgct
     4861 atagcagcta catatcttga tatttgagct ggtgtataag cattttcacc ttgtcctata
     4921 gctaagttga atgtatctgc agtactccat tttgcaaaat taaaataact aaatactgct
     4981 aaatctgcta cttcttcaat tctatcttct ttaacatcca atttttttag cctattcatt
     5041 gtttcaactc taccaggagt tttcttttct gctgcccagc ttacaatctc attgattctt
     5101 ttctcatatt ctttaggatt tttttctcta gttatatcaa caaaatcatt tgccatttct
     5161 ctttctaaat ttgactttag aagagcttgt gttgatttca atttatcttc tgtgctagga
     5221 actttacctg ctctttcttc tacttcatct tgaagccctg tattttggtc aagcccaaat
     5281 aattttgcat actcaagtat tttatttgca ttcatatcta taccaatgct ttttccatct
     5341 ggccatgttt tacctgtacc aattgttgcc atatatatat tacaagactc ttgtattgct
     5401 ttatataagt ttgtcatacc atggtttcct ctaccatggt tccatacata gtcaccaaaa
     5461 gattttttac ctaacattat aaccccaggg tcatttatag taaagtttgg atccagacca
     5521 ttttctaacg ctgccattga agttaccatc ttaaatgaag aacctggctg aaattcccct
     5581 tgtgtaacca agtttaaaag tggacttcct gctagtaagt catttggatt ttttggttga
     5641 agtgctttat aatcctctgt agaaatacct tttgcaaatt tatttgggtc ataattagga
     5701 taacttgatg aagctaatac ttctccattt ttaacatcaa tagctataag agctgctgac
     5761 tgtgcttttc ctgcatatgc actaattggt ttgtccccaa atttactttt aaaagtacct
     5821 cctttagaag caacttcgat tatctgtttt aatgcattat ctgaaacttc ttgtaaatct
     5881 ttatctagtg taagatacac agtatctcct gatttaggtt ttttagattc aatttcttta
     5941 ctgattctac ccaatgcatc aactttaacc attttataac catcagttcc tcttaatcta
     6001 ctttcattac tcttttctac tcctgcaaga cctaccatat ctccagtttc ataacctttt
     6061 tgaaggtatg attctatttg agtggatggc atttttccta catatcctaa catatgagaa
     6121 gctaatgacc cattaggata atatcttact ggttctactg ctattgaaac accaacaagg
     6181 tccatagcac tttcttcaat ttgagcaatc gtagtttctc ccacatcctt agcaatagtt
     6241 actggattat attgagaata tccttttgat tttatcaaat cccttacgac cattattttt
     6301 cttgcatctt catcactcaa acttttatca atttctaatg catcactatt tcttactttt
     6361 tcaaacgctt ctttggcact cagtttagtt tcttttatct tataactagc caaccaatct
     6421 ctcttatctc tttctgctgt gaacatccat ttactaacta aaataggtgg ataatatcca
     6481 ttttcattta gttttgcctg taatcttgtc gcatccaatc ttttatcttc ttgagataat
     6541 attccagctg atataagttt gtccaccaag taataaaaac tttccttagc attataatca
     6601 tttggaatac cattttctga tttatattcc ctaatatctc tgtcatatgt ataatagtac
     6661 tttccatttt ctacatatat aggaaactca tctacatatt cttcaccatt tctctccagc
     6721 aaatttataa gttttaatga tatttcattt gctcttgaat gcttatttgc atctttctta
     6781 ttaatatcgt tacctgaaac ttgaacagta aataagtttt tatttcctgc caacagtctt
     6841 ccatatctat cttttatttc tcctcttgga gcttctattg ccaacttttt atatgtttta
     6901 ttctcagcta actcattgta atattcatat ttaaatgtag tcatatagat tatttttact
     6961 aaaatagcta aaaatatcac gcccatgact atcttaatta tttttagtct atcaacttgt
     7021 ttattttctt ccatgaaatc accaactaat cttctttaag ttttaaaact gctcttttag
     7081 ataagcgata tattactaaa ccaattaaac tattcactat tggtgctact agtagacctt
     7141 ttacaaaaag tgttgatatg ttgtagcttt gataaattat actagatgta cctatattga
     7201 caattgaatc aattaaactg cctataaaaa ttaaaacgaa agtaataata taactacctt
     7261 tatatagctg atctctcatg tatccaattg catatgcaat aataaacaaa attaatgcat
     7321 ttacaccaaa aattccacca acggttatgt ctttaataag ccctattatt gctgctataa
     7381 tcccaccttc taattcatct aaataaagag agattatggt tacatatata agaactaaat
     7441 taaagcttat gccaaaaata tctatataat ttgttatact attttctata gtcataagca
     7501 caatccccaa cagacaaagt aaaacttttt tcattgtttt tatccccttt atcctatatt
     7561 tcttggttct atgactacaa cgtcatttat attcttaaaa tcaacataag gttttacaac
     7621 tacatatttt aatgacttat ctttatcatc aaccactttt tcaacttcgc caattggtat
     7681 accatctggg aagaatccaa gacctgatgt tgttattata tctccttgaa ttacattata
     7741 tgatgagtca aacatatatc cttgcaaata tcctttacta ttataactat ctttattatc
     7801 taaagtagta ttttgagtaa ttgtaccttt agcattggca tcctttgcta gtttaaagct
     7861 tacagatgcc ttagaatcca atagtgaaat tgccttacta taattgttgg aaacctcata
     7921 aactatgcca actaatccac taccattcat aactatactt tcttttttta cacctgaatt
     7981 ttttcctgca cctatgacaa aactctcata ccagtttcca tcatttttac caacaacact
     8041 tgctgaaata cttgtcgcct tatactcttc ttgtacaaag ttcagtgtct tttttaactc
     8101 ttctagcgat tctgttttat ctagtttggc atttaaagct atcatatttt ttttaagttt
     8161 ttcattttct tcttctaatt tttttacctt tttagaatta tctttaaaat ttgctacatc
     8221 tttaaaacca tttttgataa aagaaaatcc atcatttatt cccttaccta cacttgtaat
     8281 agcatctgaa gctactccta aatttactgg actaccacta gaaaatttac caattgatat
     8341 acccacaatt ccaattaaag tgatagcaac tacgcccgtt gctatcactt taacattaat
     8401 cctttttttc tcatttttgt tcttgtcaaa tctcaaggcc atcaccaact tctaattctt
     8461 agtattcatc attaatactt tttcaaagat ttcttggtct tcaacagatt tacctgttcc
     8521 aagtgcaaca caatcaagag gtgtttctgc tatttgtaca gacataccag tttcctgtgt
     8581 aataagctta tcaagacctc taagcaaagc gcctcctcct gttagcatta ttccgttttc
     8641 cattatatct gaggctaatt ctggtggagt tctttctagt gtagatttta ttgcatctac
     8701 tattgaactt acaggttctt ttaatgcttc tctaacttct gtagagcata tttctattgt
     8761 tttaggtaat cctgagatta aatctctacc tcttatttgc atatttattt cttcatcatc
     8821 tttaaatgta gaacctatgt taatttttac attttcagca gttctttcac ctatcataag
     8881 attatattct ttttttacat aagccactat agactcgtca aattcgtctc cacctattct
     8941 tatagattta gcagtaacga ttcctcctaa agatattaca gctatttctg aagtacctcc
     9001 accaatatca actaccatat taccttctgg ttcttcaact tttaatccag cccctatagc
     9061 cgctgccatt ggctcttcta taaggaatgc atctttagct cctgcttgtc ttgcagcctc
     9121 ttctatagct ctcttttcta cttctgtaac tccaaaagga acacatatag ctattcttgg
     9181 acttacaaca ccttttttat cagccgcttt ttgtataaaa tagctaatca ttgattgagt
     9241 tatgtcaaaa tcagctatta ctccatcttt cataggtctt atagctacta tatttcctgg
     9301 tgttctccct atcatttttt tggcttcttc acctactgct aatacctctt tactatcatc
     9361 tcttattgcg acaactgatg gttctctaac aacaatacct tgtcctttta tgtaaactaa
     9421 tgtatttgca gtccctaaat ctattcccat atcctttgtc atcttattaa aactaaaaaa
     9481 accttttttt tctttctttt tttccttagc catgatttta ctccttccta ctattaagaa
     9541 tcatgtttaa aacattctcc tattatttta tcacatataa agtcaaatta tcatattttc
     9601 tttaaagcta aagtataatc catctccaat aattatatgg tctattattt ctattccaat
     9661 tatttctcca catttaataa gtcttgatgt gatattttta tcttctcttg atggttctac
     9721 acttcctgaa gggtgattat gcatcactat tatcttactt gcacttcttc ttatagcttc
     9781 tttaaaaacc tctcttggat ggactaatga cgagcttaaa gtccctatag atacatctac
     9841 atcagatatt atctcatttt ttgtgtttaa aagaaccgct ttaaaaacct ctttttttaa
     9901 ataccttagg ctatccatat aatacctctg tatatcccaa ggattcctta ttttatactt
     9961 tataggttta aaactagcta ctctagagcc tagttctaaa gctgctttaa tttgggttga
    10021 ttttgataac ccaattccat ctatattaca cagctcctct attgtcatat cttctaaatg
    10081 tctaataccc tgaatatctc tatttattat atagttggct aattcaatag catttttatt
    10141 cttgttgcca gttcttaaaa gtatagccaa caactcagca tttgataagc tttttacgcc
    10201 tttggcaagc atcttttctc tgggtctttc ctctggtgcc atttctttta ccttaatggt
    10261 tgaattaaat gactttttca gataaatcac actccataaa aaagatttat actaaaatat
    10321 ttttttaata ggtcgcctaa ccttgaaatt ggaagaccaa ctatattaaa ataatctcct
    10381 ctaatttctt caactaacaa agctccataa ccctgtatac cataggctcc tgctttgtca
    10441 aatgactcat tagttttcag ataatcctca atatcctgct ctgataacgt tttaaatttc
    10501 acattgctga ttacatagtc aattaccttt ttatcttcgc acaagtttat taagctaata
    10561 cctgttatga cttgatgctc tcttccagat agtcttttta acatatctct tgcacaagac
    10621 tcatcttttg gttttcctaa aatagcattg tctaaaacaa caactgtatc agctccaata
    10681 acaacatctt cattatgttc agatgctaca gacatacttt tttcaaaagc taatctcata
    10741 actaaatgtt ttggtgtttc accttccaat ataatctcat caatttcatt tttaattata
    10801 tcaaatctta cattcgtatt ctctagaatt tctttccttc ttggagaggc tgatgccaag
    10861 attatattca tttattcacc tcatttgtac gtaatttgta cctatttagt ctatcactat
    10921 attgtaaaaa attcaacaga aatgtcgaac cttttttgtt acactattgt tatatttatt
    10981 accattagaa taaatataca taaaatagag gtatggaaat tattccatac ctctgtttta
    11041 tgtactcatt agagatatgg aaattattcc atatccttat tttgtccata ttacaaaatt
    11101 ttaatagctt tctttggaca tttttccata cataaatggc atcctacaca tttatctgca
    11161 tctaccttat gtttttcttt taattctccc tctattgcat caaacttaca ttgttttttg
    11221 cacactgtac atccaacaca aagttcttgg tcaatagtaa ctttcttttt cttagttatg
    11281 tcacctgata ttacttttgt agggcatttt gctacacatt gcatacaacc tacacactta
    11341 ttagggtcta tcttagctat tttgtcttca aatattattg catcaaattt acaagctttt
    11401 acacacattc cacagccaat acatccagca gtacattttt ctttaacagc tttaccaaac
    11461 tctttgctat tacactctac aactacttct tgactttctg gttttgtgat tattataccc
    11521 ttaggacaaa cttctttaca ttttccacaa tttacacact tttcttcatc tattactgct
    11581 attccatcaa ctatagaaat agcatcaaat ttacaagcat ctttacatgt tccaagacct
    11641 aaacatccaa atttacacat cttagcacct gagtttaaaa catttgctgc tctacaatct
    11701 gatattcctt catactcata tttatctttt gcacttgaac aagttccttt acaaataact
    11761 tttgctactt gtttctcacc tgcttcagca cttattccca ttatttctcc aacttttgca
    11821 ccaacatctg ctccacctac agggcaacca ttaactggtg cattgccttc aactatcgca
    11881 tttgcaagac ctccacaacc tggaaatcca caacctccac agttggctcc tggaagtact
    11941 cctagtatag cttccactct ctcgtctact tctacagcaa actttttaga tgcaaaatct
    12001 agtactatcc cgaagattaa gcccataatt cctaaaacta atacagctgt aagtatcacc
    12061 attttcaccc ctctttttta tagctttata agtcctgtaa atcctaagaa agctattgac
    12121 attaaacctg ctgatataag cgttataggg aaacctttaa atgcttctgg tatatcagct
    12181 aattctagtc tttctcttat acctgcgaat attactattg ctaaagtaaa tccagctccg
    12241 gctccaaatc cgtttattat tgtttctact aaattataac ttttttgaac attaactaga
    12301 gctataccaa gaactgcaca gtttgtagtt ataagaggta aataaactcc taatgcttga
    12361 tataaagatg gactcatctt ttgaattacc atttcaacga actgaactat agaagctata
    12421 accaatataa aagctattgt ttgtaagaat ccagttccag tttttactaa taaaatctgt
    12481 ataaaataag ttataattga agctagagtt aaaacgaacg taactgcaac tcccatccct
    12541 actgctgtat caaccttctt agaaactccc aagaaaggac atatacccaa gaattgagat
    12601 gttataacgt tattaacaag aacgatactt aaaaataaaa gtattaaatt catttattac
    12661 acctccacta tgctttttta cttcttaatt tattaaatcc tgcaaataag aatcctaatg
    12721 ttaagaatgc acctggtggt aatataaata ttaatactgg ttggaaagat gctccaaata
    12781 atgtcattcc aaataaacta ccatttccaa gtaattctct tactgcacct attattgtaa
    12841 gtgcaacagt aaatccaaga ccttgaccta caccatcaac tattgaaggc atagctcctg
    12901 ttttgaaagc aaaactttct gcacgagcta atattaaaca gttaacaact attaatggta
    12961 tatatatacc aagagcctta tcaagagcag gaacatatgc ttttaaaagc atacctacta
    13021 ttgtaacaaa tgtagctata actactataa atataggtat tcttatctta tctggtgtaa
    13081 tttttcttat taaagatata actaaatttg cacatattaa aactgctgct gttgaaagac
    13141 ccataccaat tccatttatt gctgaagttg taacggctag tgttggacac atacctataa
    13201 cttgaacaaa tgttgggttc tcatctatta gcccattttt aaatacttta gctaaattca
    13261 taattaaccc tccttattta ttaagagcac tattgaaaac atctatagca gcatttactc
    13321 ctgtagtaac tgctgtagat gtaatagttg cacctgatat tgctaatatt tgattatctg
    13381 ctgttgtact tccttttgct acttcaagag gctcagcagt ttttcctttg tattgaccct
    13441 taaatgcatc atccttagct tttgctccaa gacctgctgt ttctgacata ttaccaatgt
    13501 caacacctgt aacttgacct tcagatgata tacctaccat aacttcaatt tctccaccat
    13561 atccacttgg tttagctttt aaagtatatc caaccacttc agaaccatct aaaccttcat
    13621 acacttcagc tataagacca tctccaaggc ctttgtaagt atcttccttc atttctttaa
    13681 attcttttgc ttctggaagg actgcttttc taagttcatt atttgcttgt atatttcttt
    13741 gttctattac tggagctgta acctgattag tagctccaag agctaatgca gctattgcac
    13801 ttatagcaag taaagtacca cctaatctca ccatactgtt cattatttag ccacctcccc
    13861 aaatactcta tttctaacaa acttatctat aagtggagca agacagttca ctaatagtat
    13921 tgagtaagat acaccttctg gatatccacc atacattctt ataacagttg ttataagacc
    13981 agctaataca gcgtatatta tttgaccttt tttagtcata ggcgaagttg tataatccgt
    14041 aagcatgaag aatccaccta acataagtcc tccagcaaac agttgatata ttgcgaaagt
    14101 tatattaaat ccacctaaaa ggaatgttaa tataaataca gttgctatgt aaaatactgg
    14161 tataacataa tttattatgc ctttatacat taggtatact ccacctaata ataataatat
    14221 tgctgatgtc tcacctatac atccaccaat attccctatc atcatgtcag caagactaat
    14281 tccattgcta gaaatatctg ccagtcctgc tgctccattt ttcaaaaagc ttaatggagt
    14341 tgctgtagta actgcatcta aatttttacc tatccagtta acacctggtt gagtccaagc
    14401 agtcattgct actgggaatg atgctaataa aaatgctctt gcagcaagtg ctggattgac
    14461 aaagttacat ccaattccac caaataccat tttaactact aatattgcaa atattcctcc
    14521 tactagacac atccaccaag gaagtgatgc tggtacgtta aatgctaata ataatcctgt
    14581 tacaacagct gaaaaatctc ctatagtact tttttgcttc gtaaattttt gatataaaaa
    14641 ttcagtacct actgtaccaa gtatacaaaa aaacatagca ctcaaagcat taagtctaaa
    14701 gaagtatact cctgctactg ctgctggaag gagtgctata ataacttgtt tcattatata
    14761 tgaagtatct tcattacttc tcacatgagg agaagatgat actatcaact tattttccat
    14821 cgtttttccc ccttaacttt ctttatttct gagcagcttg ctttcttctc tttgctccta
    14881 tttctctctt tgctgatctt atagattgaa gtaatggtct tcttgctgga caaataaatg
    14941 agcaagaccc acattctata caatccattg ctctatgata ttcagctgtg tcatagtcat
    15001 cttttaaaga atatgcactt atgaaaagtg gttgtaagaa tgatggacat acatctgtac
    15061 atcttccaca tcttaaacag ttttgaatat ctggagtacg tgattcttcc tcatccaaac
    15121 ataaaattcc tgaagaacct ttgttagtcg ctatttcagt agtatattga gctattccca
    15181 tcataggtcc acccattata accttaccaa tcttcttatc ttctttaaat ccaccacatt
    15241 gttctattat ttctgaaact aatgttccaa cttttgttat taggttcttt ggctctttga
    15301 tgcaactacc tgttattgta gtgattcttt caaccaaagg catacctgtt ttaatagact
    15361 tagctatctg tgctgctgtg gcaacgttgt caacaactgc acctgctgct attggtaatc
    15421 caccagatgg aacttctttg cctgtacacg cataaataag ttgtttctct gctccttgtg
    15481 gatatttcac ttgaaggcca acaacttcga tttcgctata gtctttagct acattttgaa
    15541 ttgcttctat agcatctggt ttattcgttt caattcctat aaatcctttt ttgacatcta
    15601 ataccttcat taatgctctt aaaccaaaca caacatcttc tggattttca accattaatc
    15661 tgtggtctgc agttaagtat ggttcacatt ctgcaccatt taatataact acttctgcct
    15721 tgctatctgg tggaggagat acttttacat ggttagggaa tgtagctcca cccataccta
    15781 ctattcctgc ctcttttatg atacctacta tatcttcttt gctcaaatcc tctaactgac
    15841 cttttggttg aacactctca tgtaattctt ccttaaagtc attttcgata actacacatt
    15901 gagctgaacc tcctggtact tcatgttgtt caatagcaat aactttacct gatactgaag
    15961 aatgaacgtt acatgaaaca aaaccttgtt gttcacctat tttttgccca aactttactt
    16021 catcaccaac ttcaacaata ggtttagctg gtgcccctat atgttgctga agaggaatgt
    16081 aaactatctt tggagcttga gctttttcaa gtgcctttgt gttagagtac tcttttctat
    16141 atggaggatg tatccctccc ttaaaagtta agagtttcat tgttttaccc ccttatctat
    16201 aaaaaaacat tttttctgcc ttctataagt atactatata tattaaaaaa tcttaacaat
    16261 tgttaaaaaa atatccgtat ttttataatt tattttataa atcaacacct ctatattaag
    16321 tcaaattgag gaaaaggatt gcttaattaa acaatccttt tcatatagct ttctaaagtc
    16381 caaattttct gtattttatt ttatagaatt tataaacata gagtactcct gcatggatga
    16441 taaaagcaga cttttactta cactatattt ttcttcattt gctgcttttg aagctgtatc
    16501 aattttttca ttcacattct ttacatactc tattaaatta tctttaaata aacgcatttc
    16561 agaataatca atcttttcag cttcttttga tatattttgt gatattgcct ttctatttgt
    16621 caaaatagta ttatattttt ccatatctac attattttca gcattcgacc aaaaacttga
    16681 ttcttcttta aagtttgtta ttaatttatt taattcttta gatatactct ctatataagc
    16741 gtagttactt gtatactcta aagacaacat aggtgcatct aagtgtgata aaaatgcatc
    16801 tggaaacacc tttcttacac tgcttatctg ctttctaaca tcattttcat caaaagagga
    16861 ataggtctgt atttttttta ctccatcctt ctccataact gaaaaaggta tgtcattatt
    16921 aactaatgat gtctgtattt ttttcaaatc atcattatta tctattgcag caacttgaat
    16981 agtatacata tcccagcctt ctatagtagc taatttgact tcttctggct ctttagtgtt
    17041 atttaccgct ttttctggat tagtttcttg tttatcatct gaattggttt gtgatttaga
    17101 ttttttccct ttttttattg aatttaattc atcagatata tctttataag ttatatctga
    17161 tgaattattt agaaatggta ttttagccga tacatactcc aatatcttgc tatcttttat
    17221 ttttgtataa gaataatagc caattagaca caagcaagca atcgttataa catatttacg
    17281 taaatcaatc ttatgtctat tattattaaa tcctctgtat atcgtttttc ttctattcat
    17341 tagtttgtcc ctcccaaaat tatattatta ataaagtata tttttaagag tcacaattta
    17401 tgaatataaa taattatttc ttctaatttt ttaataagaa attgtactta ctaaacaaat
    17461 cttcttgcac caagtaatac tttagaccaa tatgaactag ttaaattatc cactttaacc
    17521 ttattaggat tagtctgagt accactacaa tggataaatt tactatttcc tacgtatata
    17581 cctacatgat tagttgttcc atcaccatca gtgtcaaaat aaactaaatc tcctggtgca
    17641 taatttccca tagaaattgc acttccaaaa ttagcctgtt ctctagaaac tctaggaata
    17701 gaaacgccta cagaatgttt aaaaacatac tgtgtaaatc cagaacagtc aaatttatca
    17761 ggtcctgaag ctccccattg atatggtatt ccaataagag tatatgcaaa atctacgatt
    17821 gttgaacctt ttgctgtaga tttatctgaa tttccagtaa atgatggctt tgagttacta
    17881 ttagattgag aattttggtt agatgatgaa tttggttttt cttttgtatc ctcattagtc
    17941 tcagaaatat aactggcact cacccatcca attgttccac tcgataactt taccttatac
    18001 caaccattac ttttagcttt taattcaaca acatctccac catttaattt tcctattata
    18061 gaatagcttg tcccaggacc acttcttaca tttaaactca cagcagatgt taccttacca
    18121 ttcttgcctt caattgattc ttcgctagat ggttttttat cagaattatt agtactattt
    18181 gaattactag aattgttcgt tccaacatct tctgatgttt tagaaatata ttggctacta
    18241 gcccatccag taactccatt tgatagtttt attttatacc atccattgct ttgttctagt
    18301 aactttacta catctccatt atttgcttta ccaactaatg aatagttagt acctgcacca
    18361 cttcttacat tcagtctaga actcacattt actttaccat ttccactaat agttgtccca
    18421 cttgaagttg gattattttg acttgatgta ccttcagacg aaccacttgt tgatatgtat
    18481 tttgcacttc cccatccaac aacagaactc gataccctta ctttatacca tccattagac
    18541 ttttctaaaa tctctacagt ttttcccttg tataattttg ctaccttatc gcaatcagaa
    18601 cttggtccac ttcttatatt caaggcactt gctgttactg ttcccttttc aagagcactt
    18661 gcatttatgg agctaacaga tactgctact gccccaattc ctaaagctgc tatagctttt
    18721 ttcactacta tcactccccc caacaaattt ttatagtcat aaattcataa cattattatc
    18781 catttttagt ccctacaatt taatgataac ttattttctt attaattgta aagaaattat
    18841 aaacatatcc ttaaaattag tgatttttag gaagtatttc aatccaataa ttatctgggt
    18901 ccgctataaa ataaattccc atactttcat tttcaaaaca tatgcaatct aaatctttat
    18961 gaagtttttt tgcctcatca aactcctcaa cttctaaagc cagatgaaat tcattgtctc
    19021 ctaaattata tggtctatcc caatctctaa gccaagttaa ttctaatgta tgactagtaa
    19081 tgccatctcc taaataaact aatataaaac ttccatcttc tgcttccttg cgctttacct
    19141 ctttaagccc taaagctttt ttataaaaat ctaaactttt ttctaaatta gtaacattga
    19201 aattgttatg acaaaaatta aacttcattt tgaaatcact ctccaatttt tatttttttt
    19261 atattatatc attattataa atttatttaa atcatattaa gttaaaaatt tgaatgatga
    19321 tgaccaatta ccaaatcatg gtaaattatt taaaagaata tgtcaaaaaa agaataagct
    19381 ctttcaaatg cataaaaaat ttatacccaa gttatactta atcatgcaaa ttggcagaac
    19441 ttattcttta aaactctaac ttttaagttt ttctttaata atataattta ttactttttt
    19501 tctaatatct tcagcattat aatcatcttc tacttctata tccaaaagtt ttgctattga
    19561 cctcatatct tctctagtct ttgacctata gcttgatatt aattcatctt ttattttctc
    19621 tggttctaaa agatattctt catctcctct tttgaaaaca acgtattttt gagcatatga
    19681 acttctattg tagtatatat atcttgatat ttttcttaaa atttgattat atgaaagtcg
    19741 cttgttaata tcaagtttta agtactctga aaaagcaaat agctcttttt ttgatttaaa
    19801 taatgcttct ttctttatag ttcttgatat tgaagttaca ctttcttgat atgcacactt
    19861 ttttaacatt tttaaatata ctctattaag accaatactt tgattgaatt tttttatatt
    19921 attattaata atcttatcca agttaccttc aaagtatttt tttgctcctt tttgtgatac
    19981 ataactctca agttctttgt gggccatatc aagtatcatt ttttttaaat cctctttata
    20041 tcccctagat tccatgatac tccctccctt agctatttat agtatattca aaaagctcaa
    20101 gaaatgtgag tcattacaaa atttttttac tttttatgta tatattaatt taaaagggga
    20161 gataatagta atgtaaaatc aaacatactc aatctccccc atttttagac ctctattact
    20221 cccccaatag aggtcttttt ttagtttatc aatttctatt caattccctt tagttcaaat
    20281 cctaattctg ctatcacttc ttttaatttt tcaatagata catcatcttt catatctaca
    20341 gatgcacact tattttctaa atctacatct aaaacttcaa taccatctat atcttctgtt
    20401 aatgcagttt taagatggtt tacacaatga ccacaactca taccttctac taatagtttc
    20461 ttcttcattt aattacctcc ttatacccta taagggtatt ctatcatata gtttatactt
    20521 tttaaataga aattaatcat ttaatttgat tcattcgatt ttatatctaa attagatatt
    20581 ccctcatata catcaaaatc atttggagta attttacctt ttaatctact attacttaca
    20641 atatagttgt ttctcacagc taaacttata aatgttgcat tatcttttat atatgtctgt
    20701 acatctttgt atgctttttt tgtttcaatt tcagacgtag aacttgtaag tgcagacata
    20761 tatccattta acttatcatc agtatatcca ctactcgcta taatactact tgcatctggt
    20821 ataattgata gtttccatcc aactaatgct aaatcataat ttttagaatt aagagcattt
    20881 tccatatcct tatctgacag ctgatttact gtactattta ttcctatagc ttttaagttt
    20941 tcatttatta tgtttgcagt ttttattctc tcactattat ctctgtttac tattatcttt
    21001 aagttcattt cagaaagact tttctttact tcctcttttt ctctattttt tttctcttca
    21061 gcttcttttt tgattctatc ttcttctgct tttttagctt ttgcttcttc ttctggcgta
    21121 agcttctttg agttcttttt agctgatttt ttctgatttt ttactttatt gtcattttga
    21181 tttactgagt ttacatttgc atattctacc ttagcaagac actctatcgc cttatcttta
    21241 ttaaactcta aatccttcat ttcactatta tagtattttg attttgaatt aagtggaaaa
    21301 ttaactggag tagcatcatc catataacct tcactaataa ttctatcttt atctatagag
    21361 tgtgcaattg cttttctaaa attaacatct ttgaaaaaag gattattata attaaataat
    21421 acacactcat aatctcttcc ttgatatttt gttatattaa actctttttc ttgaaactta
    21481 cttaaatcat ttaatgtaac attggttata tcactatcaa gagccataac catagatgtc
    21541 cttgcatctt cattaggcac catacctact tttatgttct tcatggtttt tggaacttct
    21601 tcatagtaat ctttgtttac agataaaacc attccttctc tttctgtata tgattctatt
    21661 ttatatttcc catttcctat catattatta ttcttgtcat ttacatcttt tgaatctaaa
    21721 tgattttgag atacaattgg aaaaattaaa ctatcaattg aaaaagcata tctagcttta
    21781 aattttattg taaaatcttt atctgattta atattcacag aagctatatt tttagtaaat
    21841 tcattatatg gactatctgc acttttttga attaaaccaa tagtatagtt tacatcattt
    21901 gaagtaatat tttttccatc atgccacttt gcatctttta gctttatatc tatactcatt
    21961 ccatcctgag ctatattata ctccttaact aattgaggaa ttacattgta gttctcatct
    22021 atagtaaata aactatcata aactaaattc attatataac caacagactt atcagtatta
    22081 gttataggat ttatagtttt tggagttacc attgttaagt ttatatactt agcatctata
    22141 gaactttgac tttgtaaact tgaatcacta ctactttgtt ttgttttagt attactacaa
    22201 ccagctacca taagagttat agctaaaacg actgttaaga cttttattct cttcattagt
    22261 tttttccttt cttgccatat atcttattat aatgttcgta attatttttt actttttcta
    22321 catattttga agtttgctta aaaggtatat catgtagatt ttcgccatct ttactatatt
    22381 cattattttc taaccatttt ttcacattac ctgaaccacc attatatgca gctatcacta
    22441 aatctaattt accaaattct ttgtataact tacttaaata ccaacagcca agtcttatat
    22501 tagtctctgg gtcgaaaata tccacatttt ttaaatttag ttcctctgct ccccaatctc
    22561 tagttatgtc taatatttgc attaatcctt ttgcttcctt ttttgaaaca gcagaactat
    22621 taaacttact ttcggcttta ataacactgt aaactatatt ttcatctaaa ttaaattctt
    22681 tcgaatactt ttctacatac tctgaatatt ttttaggata taaaaattta tgtattactt
    22741 tgctttccat taatagtgcc ccaaataaga ttataaaaat agatagaatc aatactttct
    22801 tactattcac gccaattctc cttcatgtac tcaataaatt tatgtgcttt actttctaat
    22861 tcagttattg ttcccgaatt atctattata taatcaccat atttggattt ttcttcctga
    22921 ctcatctgtg aatttatcct actaagtgct tcctgctcac tgcaattatc tctcttttgt
    22981 attctactaa tttgtacttc ttgtttacaa gtaactacta atagcttgtc aaccatatct
    23041 aaaaaaccac tttctaccaa tattgccgca tctaacacta ctatattttc gccttttttt
    23101 ctcaattttt ctatttcact tattattttt tctcttattc gtggatgagt caagttattt
    23161 aattccttaa gtttttcttc atcactaaaa actattttcc caagagcttt tctatttaga
    23221 gttccatcat cattttttat actttgccca aaatggacaa atactttttc caataacaac
    23281 ttatcctcaa atatcttcct ggatataata tcagcatcca ctataggaat gttaagattt
    23341 ctaaatatat ttgataggct gctttttcca cagcctattc ctcctgtaag tcctaatatc
    23401 aacataaaat cacctacttt gtctcatacc aagaactacc tacatttaaa tctacatcta
    23461 agtgaacatc catatttaca gcattttcca tttcttcttt tactattttc ttaactatat
    23521 ctatttcatc atcaattgct tcaactatca actcgtcgtg aacttgtagt ataagttttg
    23581 atttcaaatt gttctcttcc aattttttat gaacatttat catagcaatt tttattatat
    23641 ctgctgcact tccttgtatt ggtgcattca ttgcaaatct ctttcctcta tttctttcca
    23701 taaaattgct tgactttatt tctggtatat atcttcttct gtttaaaatt gttacagcat
    23761 atccatcctc actagccttt tctactgttg tgtccataaa ctcttttatt ttatggtatt
    23821 tagcaaaata actttcgata tattctttcg cctttggaac aggtatattt aaatcatcag
    23881 ctagaccaaa gtcactttta ccatatataa taccaaagtt tacagcttta gctgcacctc
    23941 tcaattcact agtaacatct tccataggaa cattaaaaac ttgtgaagct gttttggtat
    24001 gaatatcttc atgatgttta aatgcttcta tcatattttc atcctgactc atatgtgcaa
    24061 gaactcttag ctctacttgt gagtaatcgg catcaaccaa cttacagtta tcatctgcaa
    24121 taaacacttt tcttattttt ctacccattt ccatttttat aggtatattt tgaagatttg
    24181 gttctgtaga tgaaattctt cctgtagtcg ttatagtttg attaaatgat gaatgtattc
    24241 tattactttc tggatttatt atatttaaaa gtccttcaac gtaagtagaa tttaacttta
    24301 ctatttgtct atactcagtt atcttatcta ttattggatg cttatctctt aatttttcta
    24361 aaacatctgc attagttgaa tatccagttt tagttttttt aattattgga agctctaatt
    24421 tttcaaataa tataacaccc aattgttttg gtgaatttat attgaatggc tctcctgata
    24481 attcataaat ttccttttct aatgtagcta ttatttcttt aaattcaaca ctcaattcat
    24541 ccaatatact tttgtctact tttatacctt catactccat atgacctaag acttctacta
    24601 aaggcatctc tacatgataa aaaagaccat ccatactcat atccattaga cttctttcca
    24661 tcataggaac tgtttcttta actgtgcata ttatttgacc catatactct gctaaatcct
    24721 caaattctaa atcctcatag tttttagatt taacaccctt tcctaataat tcttcttttg
    24781 atttaacctt ttttgataaa tacttcatag ctattgcact acaatcatat gaggtagatg
    24841 aagttgaatc tattaagtac tcagctattg ttatatcaaa atacatattt tctaagttta
    24901 tattatatgg ttttaaagat atataatcat cttttaaatt atatccatac tttttaattt
    24961 cattatttga aaatatacta tctaactttg acacttcatt tgaatctaca taatatattt
    25021 tttctccatc tacacttata aaaatatata ttatattttt ttcaagtata ttaccttgtc
    25081 ctctaacagt ttttaaaata acttgtcctt ttttgtttac ttcatctata aatttttcta
    25141 tatcttttaa ttttaatatt tctatttttt cttctacgtg ttctgtgtca tctgaatcga
    25201 ccaaatcaac taatcttgat aagagacttg taaatccaaa gtatctaaat ttatctaaaa
    25261 gttcatcttt atcataatcg ccaaaaatca tactatctaa atccacttct attggcacat
    25321 ctcttataat tgttgcaagt cttttacttt gaatagctat ttctttgttt tcctctattt
    25381 tcttttttac actaccttta agcttatctg tattctctat tagattctct atactagaaa
    25441 actcttttat aagctttata cctgtttttt cacctattcc aggtactcca ggtatattat
    25501 cagacttgtc tcccataaga ccctttaaat cgataaattg tgttggagtc atctcatatt
    25561 tttcaattac agaattaaag ttgtattctt ctacttctcc aacccctttt ttcgttataa
    25621 gggtagttgt attatctgaa gcaagttgaa tagcatcttt atctccagtt actatgtata
    25681 ccttatatcc attttcttct gcttttttag aaacagtacc tataatatca tctgcctcat
    25741 aaccatctat ttctagtcta tttattctaa atttatctaa aaggtctttt aatggctgta
    25801 attgttctgc caattcatct ggcataccct ttcttccagc cttataatct ttatattcta
    25861 aatgcctaaa tgtaggtgct tttctgtcaa aagctacact tatatgtgtt ggtttatata
    25921 tatctatcat tttaaatagc attgtagtaa acccatatat agcattggtc tttaaccctt
    25981 ctttattatt catttctgga agagcataaa aagctctatt tattattgaa tttccatcta
    26041 ttataattaa ttttttttcc aaattatatc actcctaaaa attatctatt tttgtaacat
    26101 atatattata taccaatata gtgttattta atattcccat aataataata gtatattaaa
    26161 attaaatatg ttgcaaacaa tatatttttt tgctataata atatacatga catgcccgag
    26221 tggtggaatt ggtagacgca gtggactcaa aatccaccgg actaatactc cgtgccggtt
    26281 cgagtccggc ctcgggcacc attaaaaact cctaaagcta tttattcaat agattaggag
    26341 tttttttatt tttgatttaa attttaagtt attttttgaa attactgtgt ctttttaaaa
    26401 tttatataat tatataaatt tatcttctag cattaattta aaaactaatt tacttttata
    26461 taattttcta ttttatatca taacttatta caacctttta tctaatttat tgtatacaac
    26521 aacactacaa ataaattgaa ataaaataag caatccaaga acaactaaaa cccacttgct
    26581 tattaccatt acagaaaata cactcaatat agaaacaata aatataagaa ttacaagaac
    26641 atagcacatg atttgattag taatacgtcc agctttatca cgtaacataa ttcttctttc
    26701 atcattcatc tctatccttt gattttttat cttttcttca taatctactg ctctttcagg
    26761 tttactccaa tacatatatt gaagaatcat acatacacct ggacctaaag cagctccaga
    26821 taatccccaa ataaaagcct caaatgaaaa ctcagtaaat gtagccaata aaacaagtaa
    26881 aattccacaa ataaaatata taattccaac atataacata ttctttttca tttttactcc
    26941 tcctcataaa taaatatttc ttcaatactc atatcaaagt atctagctat cttaaaggct
    27001 aagatgatag aaggattata cctaccattt tctaatgaac ctatagtttg tcttgatact
    27061 tgcaaaatag aagcaagttc ttcttgtttt atgcctcttt cttttcttat ttcttctaat
    27121 ctatttttca catctatccc cctttaatat ctcaactacg gaaagtctac tttccataat
    27181 tatacaacta tattccattt atgtaaagct tactttccat atttacaaaa aaataacaga
    27241 ctattttcag cctgtaattt tagaatttca tgttgtttat taattttaat gttatttatt
    27301 aattccatat tatttattaa ttttaacttg gtttctgaat tggaatccaa acttctgtag
    27361 tataatcagg agcattgata tcgccattgg gataaagttc aatatctggt aaattagcat
    27421 acacataccc agaacttggt aaccactcag taataattct tttttgcaat tcctgtattg
    27481 ccagagcatt tggcattgga gaaacacatt caaatactgc ccatgtgcct gatggtatta
    27541 agtattcatg agtatcttct aatacaggct tatctgttgg agcagcaata taataatcta
    27601 aacccttact atttgtacac acactaactc caagcaatcc acaaggttca ttatttatta
    27661 actctgaaag tttatcaatt gttccatttt ttatgcattt agcccacaac ttaggaactt
    27721 tctcaaagca ctcttctaca atcatgttca tactttcttt tataccaaca atacgaaacc
    27781 ctttcttttc tacaatacga tattgcattt ctatatttcc ttttacataa atgcttaatg
    27841 tcatcttagg atatgctttt aaaacaacac cctttgctct agctgcagat ggagaaatgt
    27901 tatgtatatt ttgaaaagct ctattaaaag atgttggtga atcgtaacca tacttctcag
    27961 atagttctaa aattttgatg ttactgttct gaagttcaaa tgcagcctta gtcatacgtc
    28021 ttcgtctaat atattcagat aatggtactt ctgcaatata tgaaaacatt ctttgaaaat
    28081 gaaaggttga acaacatgca atttttgctg cttctgcata atccactcca ctttcgagat
    28141 tttcttcaat ataagtaata gcttgattta atttatttat ccattccatt tgatattacc
    28201 tccaagcaaa ttatacagtt taataaaata atatacctct ctattcatgc acaaaattgt
    28261 aagcatttaa atttataagc atttttcaat caatacaata aatataaaaa ttgtattata
    28321 caataaaaaa gttcaataac attatattgt aaaatgttat tgaacttttt ataaaaatta
    28381 atttaagtgt agttaaatta agtattacac tatcttatat attacaatat cctactatct
    28441 tatagtcttc tggcacttta taatctttgt ctggagtacc taaattccat tttaaatcaa
    28501 acatagttgc acttattatt gttgcaaaat aaagcataac tataccaatg tctatttttt
    28561 cttcatataa attagtatga ccatcttttc taacagctaa aactacagtg cctccatcaa
    28621 ctataaatct ccatggttgt ctatttaatg tagatggagc taatcttgca tagtgaaatg
    28681 catcaagaag tgctctttct tctaagattt ctatacttgc aacatttccc cattcgttca
    28741 tataaacaac atcttctaca cctagtctag tagacccctt atctgttaca acttgcatat
    28801 cagattttga ataattttgc ccagtttttg tagcatttaa tactttagca ttacttacat
    28861 tttctccata tccaatagct ataattcctg ttacctcttt atctgaatta attccaagtt
    28921 tttcttttac cttttttcca tcttcaaaag taacccaaca agaaccaatt ccaagttctg
    28981 ttactttaaa gattatactt tctcctatgt accctgaatt ttcaatgtaa ttatctttta
    29041 tgtcagataa tattataata taacttggag aatctatcat atttcctttg taccctgcta
    29101 ctttatctaa attattaaaa acttcacttc tattcataat tcttacatca acatctattt
    29161 ctggaactag tttcttacaa gattctgagt atttcttaat ttcactaaga tattcttctt
    29221 taatatctgt gttcttatat tctctaacag actttctatt taatatgatt gttttataat
    29281 ccataatttt atcctcccca aactagtatt gtcttaatta tatacccatt aatatattat
    29341 tttactcatt tatttaataa ataaagatta caattttgta attattattt attaataata
    29401 ttccactttt acattaataa tgaccagttg tgcaaaatcc attgccaacc accaaataaa
    29461 aacatattat aaaggtaata taaaataaca aacaaatctt aacaaaaaat taaacttttt
    29521 ttacacgaaa gaaggcttcc cgttgccttc tttattttta taaaaaaata agctgtttct
    29581 aaaatgattt cacatttttg aaacagccaa gttattctat aatgacaact ataatttgag
    29641 gatgtgaggg agagttgtca ttataaattt agggtaatta tattatgttt taagctagtt
    29701 ctttctatat ttatataata cattttatat atgaatttta tatgagattg gtataaatga
    29761 tatatgaaat tacatatgtt tatattatat taaattttat tattacattt tccacaacaa
    29821 tactcatatg tctccacatt atttggaata tttacaaata caaattcttt acagttctca
    29881 caatacttta atatagatat agttccacaa gtgtaacatt caaatattac acaatcctca
    29941 ttttcctcta ctatttcaaa ctttttacta tgttcaccac actctgggca cttgtgatta
    30001 tttacattca taaatactcc tccttattag tatagttaca tgtcaaaaac ttaattaatg
    30061 tattctatat tacttattat atattctata ataaatcata ttctaatata ataaaacaaa
    30121 ttaaataaaa aaaaaaccat aaattttaaa tttatggatt aattcttgta atgataactc
    30181 tatttgagga tgtgagggag ggttatcatt acaatagggt attatattat ggtttttaag
    30241 ctagtctttc tacacctcat atgatacata tgctatatga attttatatg atttttacat
    30301 aaatatttta tgaaatttaa attttttagt cattttgaaa tttgtaaaaa gttctctaaa
    30361 aatccacagc atcataaaca gccaaaattt aagtaaaaca tcataaaaaa atttgtccaa
    30421 taattttaac aagtaatctc acctcattat aattattgac acaaacttaa ataaacaatc
    30481 tataaatctt ctataaatct taaactttcc ccctattgat acacaatttc tagtttgtca
    30541 attttatttt gcatttctaa gaaaatttct tcaacagaat tgttaaatat attgcctaaa
    30601 tagattcttt tatctttttg aaatgaataa gattttacac taccatcaga agaaatatat
    30661 aaatgactcc actctgctcc atattttgaa aacctctcct ttgtatcttt aaacctcata
    30721 tcttctattt ttattgcttt ttctctgtct cctcttacta cagtgtgacc cctttttatt
    30781 aaactggtta tttttatatc ttcttttaat ttaatacgtg tatcatcatt ttttgaatat
    30841 actttccata tcactttatg acgataatta tctaattcct ttattaagct tctatcaata
    30901 gtaaaactat ctttagttac cacaattaaa tcaaaatggt ctaacatata ttgaaatatt
    30961 tctctcatac ttttattttt taaaatatcc tcaccaataa cctctataaa tctacagcct
    31021 ttctcataca tgcagttcaa taaacttgtg atttcagaaa aataatcatt tgtattatta
    31081 tctccatcta tttctatagt aaagtacaaa ggagtaatgt atgatttatt tcctgttatc
    31141 tcaaatacac ttgatagtgt ctgtatatca tcttcaaacg ttaagtacac attctcataa
    31201 aacataaaaa attccataac tttttctttc atattatgga tatttctata tctattggat
    31261 aatatattta ttatatcgtc agtagtattt ttcccatcac attcagccag tataacaatt
    31321 tgcttccaac ttaagctatc cacatttccg atactttttt tatatccatc ttcttcgtca
    31381 taaataggac caattataat gttttctttt ggccacagat gaaccctagt tccatctttt
    31441 aatttcggat atttattttt tacagactca taaaatctac ttgtatcacc catgattctt
    31501 tactaccccc catagtttaa atattctatg ctaaaaatag cactttattt ttattaattc
    31561 aacaattatt caaaattggt cattatatat gtttaaatgg atttaacatc aaccttattt
    31621 atatgttatt gatgtttata tatgttatat aaaatcttat ttctcatact taaatgtaat
    31681 cttaactatc tctggtttac aattaagcct aattaaaact tttgagcctc ctaagccttt
    31741 atttaaaatc atagtgctat tatctttttc atattttccc cagtcatact taggaaagaa
    31801 ctctctattt ggagataata cacctccaac aaaaggtatt cttattatac ctccatgaac
    31861 atgtcctgct aaaaccaaat ctgctcccca ttttgcatat ttttcaaaga aaaatggtgt
    31921 atgtgctaaa agaatgttat attcattttc attaacttta cctagattgt cttctacaaa
    31981 attgtcactt agttctaatt ttttgttatt agcaaataaa tatggatagc attccaatgg
    32041 tataattaaa ccatataaat taagatggct attacctcta tatattctta cagattcatt
    32101 ttccatattt attattttct ttgaatatag ttccttaaaa taatccttat atagatgttt
    32161 atactttttt attaaagatt tttgttcatg atttccaatt atatgatata cttcatattt
    32221 ttcaaccaaa ttatctatta aatctaatgc aacttgaaaa tttttatttt ctccatctac
    32281 taaatctcct gttataaata taacatctgg gtttaatgat tcaattttat ctatcaatac
    32341 cttattattt ttatcaaaca ccttattatg taaatcactc acttgaacta ttttaaagtt
    32401 atcaaattcc tttggaattt ttttgttgaa aatagtatat tctgtcgttt ctatatgctg
    32461 agtttcatac ttatacagaa tatacaataa tattaatact aatactgtca ttgaaacctt
    32521 tataatcata ttctcttcct ctttattcta ttttgttaat attattataa tgcttttatg
    32581 ttttttttaa aacaataaca tcatcacata catataaatc ttttcgacat tataaaaata
    32641 agttatcctt ttctaaaatt ttcatttatt ttagaaaagg ataactataa aattatctat
    32701 aaacctctat attgtgaaat atagtttttc ctttatttaa atttttatat atatgctcta
    32761 aagttccatc aaacctaata gaatgtccag actctaaaat ataagttttc ccatccacat
    32821 taaggtcaag tttaccttct attacgagca catattcttc taaaacatga ctatgtgtag
    32881 atgaaacatg agtacagttt tcctcaagct caattataaa aagttcaaac cttctttgag
    32941 ggctaaaagg gtatattgga tataacttca tgttcccttt ttgctcaaca ataggctcta
    33001 cttcttcttt ctttataacc tcataggtat ttgtattttc atttaatagt gtagtaaaat
    33061 ttattttaaa tccagatgaa attttccata aagtagatac tgtcggactt gattcacctc
    33121 tctcaatctg tccaagcatt gctttactga cacctgtcat ctttgaagct ttgtctaaac
    33181 ttatgcccat ttcttgtctc aataacctta aattttctcc cacattagga aatttattat
    33241 ccatgttaaa atcctcctga tagctatttg tattctatga tttttactcc tgtaagttct
    33301 actatctctt ttaattttaa catatgattg ttacaaatat catcaaattc atatatataa
    33361 tcttcaagcc ctaatgcctt atatttatcg attccaaatt tatgatatgg aagtaactcc
    33421 atcttgcctc ctggaacatt ttgtttgaca aataatgcag tatttcttat attttcttca
    33481 ctatcattta ctccataaat aattggcact cttataacca tagatttatt caactttgaa
    33541 agcctacata tattatctaa tataatttta ttacttactc ctgtatattc tttatgaata
    33601 ttatcatcca tagattttat atctacaaat atgtggtcta ttttctcaaa tacatcattt
    33661 accttattcc aatcaaaata tccacaagtt tcaattgcaa tatttatgcc tttatcataa
    33721 aaaatatcaa ctaattctct taaaaaatca atctgaagtg taggttcacc tccagaaaaa
    33781 gttatccctc cattagattc aaagaaaaat ataaaatctt tttcaacttc ctctactatt
    33841 tcttcaacac tcatttcttc ggtcattata caaatggcat ctttaagaca taccttgata
    33901 cactctccac ataaatcaca tttattattt atttgcgctc tatcaaatag tgaacttata
    33961 ttttgaggac aaacatctat acatctatta caggatacac atttatcttt cataacacct
    34021 aattttacta tgttactcca ggaatctgga ttagaacacc acttacattt taatttacat
    34081 ccttctaaaa atatagtagt ccttattcca tctccatcat ttactgaaaa atgttgtact
    34141 tttacaactc tacctttttt actcataatc tacctcataa ttaaaaattg ctatgtgaat
    34201 ttctagctat tatagcatct tgcatttctc ttgataaatt aacaaattga gtactatatc
    34261 cagcaaccct cactaataaa tctttatatt cttctggatt ttcttgagct tttaatagag
    34321 tatcatttga tatcgtatta aattgtacat ggaatcctcc taaagcaaaa tatgatttaa
    34381 tcatagatgt tagatttcta agtcctcttt cagtttccac caaatcttga ttcagtctta
    34441 aatttagaag tgttccacca gtatgaacat catgatttat ttttgatgca gatttcattg
    34501 ctgctagtgg acttgttgta tcagtaccaa caaatggaga aactccctct gtcaaaggtt
    34561 ttgtcgcttt tcttccacaa ggagttgcac ctactatttt tccagttggt acatagtttg
    34621 atatacccat aaatgcacta ttaaatttag agccaaaaat atccttgtat tttctagttt
    34681 cagtataata aaaatcagaa acttcaattg ctaatgaatc tacataatca ttatcatttc
    34741 catacttagg aacatccaac gcaagttttc ttaattcttc ataaccttcc caatcattat
    34801 ttagtgcttt tgttaattct tctaacgtag tcaccttatc ctcaaatact aattttttta
    34861 tagctgccaa tgaatttgaa actacaccta accctatacc agttaataca ggacctatat
    34921 tatattttgc tcctccttta cttaaatcaa ctcccttatc caaacatcca tctacacaag
    34981 tagataaaaa tggtcttggt accatttctt tatgaatttg ttgagcaaca gtagttccta
    35041 taacagaact ttttacaaga tatgctaatt gctttaaaaa ctcatcctta agttcttcaa
    35101 aagaagtaaa ttctgtgata ttttttgtat ctaaccccat tttttctcca gttaatctac
    35161 tcttaccttc attcatagca tattctaaag ctgctgcaaa attgatattt acggctgaag
    35221 tccactgtcc tgtttttcta aaatgaggaa ctacacaacc acagttactc caatctctag
    35281 catcttctgc atcatatcca tcttgtaata acatttgtgc ccctgcacta tcgctgtgta
    35341 tagcagggaa accagttcct tgttttacca atttagcaac tgccattacg aaattatctg
    35401 gtgctccttg actcactcta acacttaatc ctggttggtg agtttttaca ctttctgtag
    35461 cctttaaaca catatatgag atatcattcg ttccatcagt accatttctc tttttaccac
    35521 caacagtaag attttggaat tgattatatc ctgcaaagta atttgctgta tttgctgata
    35581 tagtccatac ccattctgat aacttaatcc aaagtgcttc tatcaattct tgagcttctg
    35641 attcagttat tttaccttct ctagcatcat tttcataata tggatacata tattggtcaa
    35701 atctacctaa atttaatgcc aatggatttt ctgatagaat accacctaat tgaacaaacc
    35761 atacaaattg tattgcttca taaaaattag ttggagggtt tgctggtaca ttcatacata
    35821 tctctgaaat ttttataagt tctaactttc tcttttcatc tgtttcttgc ttactcatct
    35881 cttttgcaag atttgaatat ctttgtgcca atgtcataat accctgtgca actatagaaa
    35941 cagatttgta aaaatctatc ttttcaatat tttctgaaac tgatatatct aattctttaa
    36001 tttttttatc tgcatcttcc ttaatccctt tatatccttt tacaaacaat atatcttgat
    36061 aatctggtgt tacttcacca actgcctgtc tccacttaga atcattatct attattcctg
    36121 tatctactaa tatcttagct gtatcttctg ggattcttgc taagaaaact tcttccaaag
    36181 attttccctt ccaatatgga aatatttctt ttcttataaa ttctatttgt tcttttgata
    36241 ttacatatgg gtcttgagtt cttttatcaa aagtatccat ttctttgtct acccattgcc
    36301 aagaaaactc tggtgtcaat atccctgttc ttctaaattt tcctgctgta cctactatta
    36361 attcattttc aaagattttt ataggaagtt ctttacatgt ctccaaaaaa gctttagctc
    36421 ttcttataca gatagcttct ccctcagttt ttttatgtga ttctgtaaaa attctagccc
    36481 tttcacaaca tatcataggt ttagaattaa tatattcttg tctaaatgct tctattctat
    36541 tagtttgact catttaaaat ccccctttgg ataatatata ctacattttt gtatgttata
    36601 acatacttta attatattat actgtccttt agcataaaat ggaagcaaaa taacttattt
    36661 tttttcatct accttgaaca cctatatatt aatacttttt ttgttaaatt tataaactct
    36721 aaaaaaattt tctatgatat attttctata ttgttatagt tatttctaat atactaatga
    36781 tttgaaatat caaatttgta tactagactt agttttaaaa ccttagttga ttgtttaact
    36841 ttgttaactt caacatgtat atccttcata taaggaagct ctacaacacc tactccctta
    36901 ttaaagtctt cttcaaccat agaaaaaatt tctttctcag ttaagttcgt attagtcaat
    36961 gacttaaata aattgtatat aaatttaata tatttatcac tctcagataa cttatcatct
    37021 tctggatact ctttagcaca gagaatatct attgttactt ttccttcttt atcgtcttca
    37081 gacatagaat agaataaact tcgaatattt ttttcaggtg gtttttcagc accatttata
    37141 gatactacaa agctaccatc tgattttgag tcagtaatac tataaccact gtctattata
    37201 gctttcgaaa atctttgaga taaatctttt tttacttctt ctctaccttt cgcatcatta
    37261 atcttttgtg agtaattatt aaaaagctcg atagattcat cttttttatc ttcaacttgt
    37321 tctttcaacg aatctttact aatttgttct gagctactta agttcttatc atatacagga
    37381 gacatacacc ctaccatcaa tgctaagcta agatttaaag ccacaatgat tgccactcta
    37441 tttatattcc tttttacttt catacacaat cctcccatca cactaaccgc tctaaagtat
    37501 tacttattgc actagaatat gtttatattt tctttatatt aaagatttat tattcaatac
    37561 atatcacctt cctatccaat tcttataact tactattagt aaaattataa gctccttaat
    37621 acagaaataa ggatgttatc ttttgttatt aaaagataac atccttattt ttttgtatca
    37681 atacatatgt cccaactggt aacttaatcg ccccaactgt cagtatcttg gtccaatggt
    37741 atatatatat ttagtataaa tttatcgata ctattttcaa ataataattc tccattatat
    37801 ttttgtaaag aagatttaat actctgaata cctattccat gtacaaactt atccattttg
    37861 tttgttaaca atatattttt attaaaagta agctgattta gtttactatt ttcacattta
    37921 agtacaaaaa atgaccttgt catagttcct ttaattctaa tatatttatt aacattttca
    37981 tccactattt tatcacatgc ttctattgca ttatccaaaa tattagaaaa tatgcttgac
    38041 acatctatag gttttacaaa atttactttt gaaaaattta tagagcaagt aaatttaatt
    38101 ccttttttta aacatatttc actcttttcg ttgattataa tgtctaatat catatttcct
    38161 gtattataga tatatttaaa tgtttttatt tcatctttta aattgttaac atattcatta
    38221 atttctttgc tattgtttct aaggttgtct atacaataaa tgtgattatt tatatcgtga
    38281 tatagtttct taactcgcat atgagattct tgaatactta aataatgcgc atattgcata
    38341 tctaacttat tttttattaa ttcagcttga gattttaatc tattctcttt tattatttct
    38401 ttaaacaata gtataagaaa tatactacta gctcctacca attttggatt aacaaaatta
    38461 tcaaaatagt atccttctga atgtaatgac ccaaaccgtt ctaatttttt taatacataa
    38521 tttacaagca tattcattgt attaactaat aaggcaaata ataaatatac ataatttctc
    38581 ttatcttggc taattaattt tatagacttc ctaaaaaagc taaatataag atatataaga
    38641 ataattatta aattactata tatctgaatt tttatagatt ctaagtgagg tactaataag
    38701 gattctttag atgaaataac attacctgta attgcaaaaa atagtattct atatataaca
    38761 gcatccaaac atttataata tacactaaat agataaaaga aaatggaata cttaatataa
    38821 cccatcttat aaaaataatt atagtatcct ccccaagcaa taaatgctaa tatataaaat
    38881 aaatagttta tattactaaa gtaatttcct ccattaaata atctacttat ctgaattata
    38941 atataaataa gaaacaagac aatatagaat actatttttt catttttttt actatccttt
    39001 ttataaatta aaattccgtt cattatagaa aactgtataa atatagataa aactactaat
    39061 agctcagtca taaagtttag catattgtat caccaagaaa ttttaagaat ttctccttaa
    39121 cttctttata tctatatcta ctaataggta cctcttctcc actttccagt attgcagtat
    39181 taggctttat attttcaaca tatcttaaat ttactataaa acttttatgg catcttataa
    39241 atttatatgg atttaattct ttttctattt tgcctaaact atattttata tcaaaattct
    39301 tgtttattgt gtgtattagc atatcttttt tttgaacttc tatatatttt atttcattta
    39361 aataaatctt atatgtatta gacttatttt ttattgtaat atgactttcc ttatttattt
    39421 caatatcttt gatacaagtt agcacatgtt tttttagttc ttccaactct attggcttta
    39481 gtaaatacct ataagctctt acctcataac cttcttgcac ataatctatt aatgaagtta
    39541 caaatattat ttccatttca ttgtctactt ctctaatctt tcttgcagta tccattccat
    39601 ttaatttttc catttttata tcaagaagta atatatctat atcttttaaa ttactttcca
    39661 gtaactcttc tccagatata tacttttgta tctcatattc tatacttata tcttttaata
    39721 tattctcaag gtaatcttct attaaaagtt gtgtttcttt ttcatcttca caaactgcta
    39781 tcttaatcat aaaatgcctc cttacataat ttctagttaa tacaattaaa atatttataa
    39841 tatatttaaa gataattttg tatatctgat actttaggat aacattttca aattattttt
    39901 atcaatactc aatcccatat aactattatt tgatatttca atttaaagac agaaattact
    39961 ataattaaaa acagtactta ctgataaaag aagatgtctt aaactattaa aaaaataatt
    40021 ttaggacacc ttcttttatt tatttaaact ttttaagcct taaataatac attaatctcc
    40081 tatataattg tactgcatat aaaatcaaca atataatctg tagtacaata gcagttacag
    40141 atgctccata accactatat aaatttctta tttcaatatt caataaatat ataaatatta
    40201 ctactaacat aaagaatata aacatattca taaataaaat tgactttact ttgttttttt
    40261 tatcagaatc actatataat ttaggaggta tgtctttgta ttctttcgac catatatacc
    40321 atgcagatgt acccataaaa ctaccaatac tcctaaatac aagattccag ccatttgatt
    40381 tatgttcatc aaaataatta ttctctacat catagtagta atcaacagtg tattttattt
    40441 ttcttggact tcccttatga aaataaaata ttcctccaaa tttatttatc ttatataaat
    40501 tatatccttt agcttcaata tcttctaacc atttctctat cttatcaggt gaactatacc
    40561 agtcaaattt gaattttatt ttcttttcca tagcactcat tctccaaaat gatattttta
    40621 aatagcttaa aaatctattt aaataattat atcattttga tactaatttt aggttacaat
    40681 catatattta aaaagctatt taaatagtaa taaactaata gccataacac ccattcctgc
    40741 aatcaatcca taaatagata aatgatgttc cccgtactct ctagctgatg gcaataattc
    40801 atctagtgat atgaatacca taattcctcc tacaattgca aatacaattc caagagttat
    40861 atcatttaaa aaatttctaa gaagtacata tccaataatc gctcctaaag gctcagacat
    40921 accagataaa aaggaataat aaaaagcttt ctttttatct cctgtggcat aataaactgg
    40981 tacagataca gatatacctt ctggtatatt gtgtattgca attgcaattg ctatcggaat
    41041 agctattgta acatcatcaa gagctgatat aaatgtagct aatccttcag gaaaattgtg
    41101 aattgctata gccattgctg taaatatacc tgttctcaaa agagacttat tttttttgat
    41161 attcttttct tctatattct ccattttctt tatttcatgt ggattttctt cttgtggaat
    41221 tagcttatca ataacagcaa tgatagccat acctataaaa aaagctatta cagttgacca
    41281 acttcctaat ttctctccca tagattttgt caaagcatct tgtgctttag gaaaaatttc
    41341 tatcatagaa acataaatca taacaccagc agaaaatcct aagcttatag aaagaaactt
    41401 agtatttgtt tttttagcaa aaaatgctat acaacttcct ataccagtag ataaaccagc
    41461 caataatgtt atcaaaaatg caaatattac attattcaaa taaatcacct tctttttaat
    41521 tgatattgat tatcattttc tttatgctat catatatatt ttatatagtc aatatttata
    41581 aaaaatatac acaataaaaa agcagagata taaacttagt ctctgctttt tctttatagt
    41641 atattaaaat tatttattta agaaatccac tgcatattgc acatataaag cagttccaat
    41701 ttctagagca tcttcatcta tattaaagca tccatgatga tgaggataac aagcaccttt
    41761 tgactcattt ctagctccta caaatgctag tgcaccaggt gctatattca taaactcagc
    41821 taaatcttct gctcctgtta ctttttcaaa tagtgttata cagtcttctc caaatagctt
    41881 aattgctgca tctgtagcta tctttgaaca ttctttgtca tttataactg ctggtgttaa
    41941 gtacccatac tctaattcag catctgctct atatgcttct gctgtagatt ttgctatacg
    42001 ttctaaaatt ccaggaattt gctttctaag ctctggatta aatagcctta ttgtaccttc
    42061 taagacagct tcactcgcaa ttacgttaaa tctagttcca gaatttaaaa ctccaacact
    42121 cacaactaat ggttccagag gacttacttc tctactaacc atagattgta gattcataac
    42181 tattgctgaa cttgcaagca ctgcatcaac accttgatga ggaagtgaac catgaccacc
    42241 tctacctttt acagtaattt taaagaaatc agcagaagcc attcttggtc cttcttctac
    42301 cgatatggtc ccagattcta catcagtcca aagatgtatt ccaaacacac tatctacacc
    42361 ttccatagca ccatcttgaa tcatagctct tgcaccttta ccaacttctt ctcctggctg
    42421 aaaaaataat tttacagttc cattgatact atccttaata tcatttaaca cttttgctgc
    42481 ccctagaagc attgatgtgt gaccatcatg accacaagca tgcataagtc cttcattttt
    42541 agatttgtat tctacatcag tgcattcaac aacttgtaga gcatccatat cacccctaag
    42601 tgctacagtc tttcctggat tagctccttt tatagttgca attacacctg tacctccagc
    42661 tgatacatat ggtatcccta ttttatcaag ttcttcttta actctctttg atgttctcac
    42721 ttcttccata cttttctcag gattttcatg aaattccctt ctaagcttaa ttacatagtc
    42781 tttataactc tttgttattt ctttaatatc cattccatac ctccaagtag tacacattct
    42841 tcttatttaa aatacttttt atcacttaaa tactatatta gatttacaaa gatacctgct
    42901 attactacag aagctattgt aactgtagta aatcctccaa caagcatctt tggaagcatc
    42961 ttatccatta aaaattcttt ttcttctggt gtttcagcca aagcctttac tgcctcttca
    43021 gttaatatat agtttggtgg aaaaccataa agtgatgtaa gcgaaactga aaaagccatt
    43081 tctttacttt cacctaaaag cttacctact ataatagaga atattcccat acctattaca
    43141 ccaaatatta tgattcctac aagaggaact gccatttcaa caagcattgc tggtgtagct
    43201 tttgctaacc ctgcaaatat aaaagccatc aatgatgtca ttaaccatcc aaatgaacca
    43261 gatttattaa gtggttttct atcaactatt ccaagttctg atgctattac accaaatatt
    43321 aaacatataa catatcttga tacaacttca tttgtaagat ttgtaaattg tactgctaac
    43381 catgctacaa atcctaatct aagtattatc atatatgtcg tatcatattt ttctggtaag
    43441 tctggtatta tcttaaatct gcttttttgt tcaggtaaat ccttaacttt ttcttcatct
    43501 gtatttacag ttacttttcc acttctaaag tctgataaaa gtctttttcc ttctttttta
    43561 agcattaatg ctgtaatagg ataacccgca aatccttgtg caacatacat caaaattgca
    43621 agtactgata aacttgcaag accttttgct gtagcagcat ctgccatcat tatagatgca
    43681 actagccctc cagtaagagg aggtgtagct attactgctg tatcccatcc aaatactact
    43741 gtccctaatg ccaaagcacc tacacatatt cctactattc ctgccaaggc tattactatt
    43801 gttttccatt gacctgctaa ttccttaata ctcatcatag ttcccatatg agttattaac
    43861 aaaagcatac ctaattgagc taatggtgtt cctaaagcgg ctaagtccac aatattttct
    43921 gggaaaaaag tccaaaatcc tactataaat ataattgctg atacaaaaac cgacggaaca
    43981 aaagctttag tttttgctga aactatatct cctatcgtca gtgatactaa aactagacaa
    44041 aaagctgtta ttgcctccat acaaaatccc ccctcataat aaatatattt ttataaaatg
    44101 tatgtatagt tatccattat tttactactt ttgaaaaaca tttcaagtca aaattcgatt
    44161 tttttcataa aattcgataa attccataaa ttaaagttag ttttctaaat tattcttttt
    44221 gtaaaaacgt tatcccgacc attggctatt taactctatt cttacaaaga gaattaaatg
    44281 taatttgcaa aaaataaaac ataggataca ttttattcat aaaacatctt ataaatataa
    44341 aatgaattgt ctttatgaat cttaatatat cctatgtttg taagtttaat gtgtatgtta
    44401 gctatggtgt aaaatttgta tactagttat tgtgtaacct actatatact ccatttttgt
    44461 ttactagctc ttcatgagta cctctttctt caattccttt atccgtcaat actatgattt
    44521 catcagcatt ttttatagta gtcaatctat gtgcaacaac taaatttgtt ctatctttac
    44581 ttaattcctc taaagactct tgaatttctc tttctgttac attgtctaaa gcagatgtag
    44641 cctcatccaa tattattatt ggaggattct ttaaaaagat tcttgaaatt gaaattcttt
    44701 gtttttgccc acctgataat tttacgcctc tttctcctat ataagtatca tatccatctg
    44761 gcaaagtctc tacaaagtca tgtattctag cttttttagc agcagctatc atttcttcat
    44821 ctgtggcatt agggttccca caaagaatat tatctcttat agttcctgta aataaaaata
    44881 catcttgttg aactatacct atattttttc tcaatgattt taaactaaca tcttttatac
    44941 tctttccatc aatttttata tcacccttat caaattcata aaatcttggc aataaattac
    45001 ataatgtagt ctttcctcct ccagaaggtc caactaatgc tatagtctta ccagctttta
    45061 tagataaact taaattatcc aaaacttgag tcttatcttc atatgtgaaa gatatatttt
    45121 ctatctcaat gtcacctttt acattttcaa gttcaatagg atttttagct tctttttgat
    45181 ggtcttgttc cattatctct atgaatcttt taaaacctgt cataccattt tgatattgct
    45241 ctgtaaagtt tattaatttt ttcataggtt gtataaacat ttttacatat agtatataag
    45301 cagcaaaatc acccaaagta atctttccta tataagtaaa ataaccacca gctattacaa
    45361 ctacccactc taagatatcc atgtataaat tcataccaga gtaatattct gccattacct
    45421 tataagaatc ttgtcttgct cttctaaata atttattgct tcttacaaac ttatttaact
    45481 cttctttctc agtacaaaaa gacttagtta ccttcatacc tgctatacta ttttctaaag
    45541 tagcatttac atcacctata gtaactctac tcttcataaa agcaatattc atcttatctt
    45601 ttttagctat tgcaaaccaa attataaacg gtaatatagc aaatattata agcgtaagag
    45661 gaatatttat atctataagt ataaagaatg aaccaaccaa cattactata gaaatgaata
    45721 aatcttcagg cccatgatgt gcaagttctg ttatatccat taaatcattt actattctag
    45781 acatagttac tccagatttg ttattatcaa aatacgtatt tggaagtctt tgtaagtgtg
    45841 taaatacctc atttctcata tcagcttgca tatctacacc aataacatgt ccccaatact
    45901 gcataaaata gttaagccct gcttttgcta taaatataag tataagtgct actgcaaaaa
    45961 ctactaacat tcttaagttt ttatttggaa caacgtcatc cattatattt ctagttatca
    46021 taggataaac taaatcacat aaggaaaata gaaaagctgc tataaggtct agtgtaaaaa
    46081 ttttcttata tggcttataa tatttgacaa attgttttat cataagtatt aaatccctcc
    46141 tttattagta cttctattag tacttctaaa aaatacccat aaattagtat aacataacaa
    46201 taactttaaa tcttttataa acttacaaag taataacaat ctttttcata aaattgaaga
    46261 tttatatcat atagttgtat acttgaaaca acataaaaag agctatatct ctatatttaa
    46321 aattttataa agatacaact ctatatttaa tactaaattt tttttataaa tacaaaacta
    46381 cttcaatgca tttaatatct ttttatctaa tgctgttgta tttatacctg ttatatatcc
    46441 tgttgccttt attgtaggta tatcataagt tgttggtagt atagtagtag atacgattaa
    46501 atcagcacct tcttgttttg ttgaacattc agcaatttta cattgctcaa cttctgcttg
    46561 tatattattt tctttaacca atctttctac tctgtcacaa actattgttg atgttgcgat
    46621 tcctgctcca caggctacta atattttttt catatattgt cctcctacaa tttctttaat
    46681 attttataac tcaaaataaa attgataaat ttcttatatc tttatttata taaataatta
    46741 tatcatttta tataagaaga acatcttaaa attattcttt taatatgttt tttatttcaa
    46801 cattgcttat acttaaaatt tcatttttta tacaagactc tatgtacttt gatatatttt
    46861 tataatcatt taaattaaac tgttcaatat tcaatttata ttctatatca ctaacaatac
    46921 ctatcaaatc agacttatta gataaaatat cctcatactt accttttcta gttacttcca
    46981 gtcttttaaa tctataattt ttatatcctt ctatgataat caagtccata tcttcatata
    47041 attgaatcat tttatataat ggattcttct cttttagttc ttcaatatat gctactcgtt
    47101 tatctgatat tatacagact tttctcgccc cagattttct atgtttataa gtatcttttc
    47161 cttcctcatc catatcaaaa tcatgacagg tatgtttaat aactccaaca cgataccctt
    47221 ttttatttaa ttcttttatt atgccttcaa tcaacgtagt tttacctact cctgaatatg
    47281 agacaactga caatatatta tacataaaat tgtgtccttt cataaaacta tctaataaca
    47341 acatccacta attgattttc ttttattgtc tcattctttt taatcttaat catacaatta
    47401 cttcttagag ttgcagatag tctagctttt gcatctttct tatcatttag ctctacatac
    47461 aatttacctt cacttgtata tagttttcca cttacaaatc tatctttatt tgaaaattta
    47521 ttaaattctc ctttaaatat agcttttata tgatgtgttc ccttcttata tgttaaatac
    47581 tcaataacag gaactatcac attatcaaat accactattg ctgcatgtgg attaccagaa
    47641 agaccaaata atagcttttc tcccaatgta cctacataac aagctccacc aggtttaatg
    47701 tttatcttcc aaaataattc tgttgcccct atttttttga atacatctgg aattaaatct
    47761 ttatctccaa cagaaacacc acctgtggta attaaaaaat ctacactctg taacatattc
    47821 tttacctttt tttctaactc caatatatca tcagaacaat tgcatattgt atctgcttgt
    47881 attccaagtt ttaataatct tgaatataag gtatatctat tactatcgta tattttacca
    47941 ttctctaaag tctcatttat atcttgtagt tctgtacctg tattcaaaat tccaactttt
    48001 aaatcatcat aaacagttac tttggatatt ccaagacttg ctaatactcc aataccatca
    48061 tatcctatat tctgattttt attaataatc aattgcccct tttttatatc ctcaccctta
    48121 aatatgtaat tatcgtattc ctttaatttt atatttaaag ttatcatatc acctataact
    48181 gttacatctt ctttttttat tacacaattt gcaccctgtg gtatctttcc accagtcatt
    48241 atcttcactg cttcattttt atttaatacc ctattaaata catctcctgc atacaaagtc
    48301 cctataacct ttaaatttct attttcagaa tttgcattat atgcataacc atcatagggt
    48361 gacctatcaa atggaggact atcaattgtt gaatatatat cttctgcaac taccttattt
    48421 actgcatcta taagatttac tatcttgacc ctgtttattg gtaaaacatt tttttcaata
    48481 atttttatgg catcttctaa ttctatcatt ttaaatactc cccaatatat tttttattta
    48541 agatatttct atgtaatata ttatagatta taaaagttgg aaatactttt atcttatatt
    48601 taattataac taatagttat ctataagtgc agttcaaatt ttataaatct aataaaaaaa
    48661 ctgttcccag ctagaaattt ccttctatct tgaaacagca tcatatgctt tagaatattt
    48721 tattctaata aagttccttt tattattttt acaattttat cactttcaat agtttttata
    48781 gattttattt tgttatccac aatacttatt gtaagtacct ctttttttaa tattttgtta
    48841 tcttctttca atctataact cttaactact ttactgcctt catgattata tgctgttaaa
    48901 tcataattcg catctcctac aatttcattt attctggaat cttcaacacc aacatactct
    48961 cccaggtcaa tatgtctaaa attttctagt gatacagccg atttttcatg gtcacttttt
    49021 tcaatcacta tactagattc agcatcaatg actgatatac cttgtgatga gaaagaattg
    49081 gtttcaacat tgacaacttt attttcgtta atatcaacat ataaagcact tccatctagt
    49141 tcatcatttc cagtatattt tggataaact aatgtcatat aacttgatgt atttatatct
    49201 tgcattgtat ttgattcttt taaaacttta ggttttatat aataaaatgt attataaggt
    49261 atacccatat tctttataat gtacttataa tctttattca taatttcatt aacatcattt
    49321 tgaacttttg tcatagtttt ttgctgtgtt gctttacttg ctacttgatt tttctcttta
    49381 gtattttctt tatgacatcc aacaagtata atacctaaaa tagttacaca aactaatgac
    49441 ctttttaact tcataaatca atcctccttt cttaaatttt atagtattta tctatatctc
    49501 aatttacagt tatctctttt ttcaataatt atatttatta tattataaaa taattatata
    49561 atatttattt gaatttaata agattaagaa gctaattgta atttttctgt aataaaaaac
    49621 actttaaagt tgaattttga aaattcaatt tacgatattt ttattgtaag taccttacaa
    49681 cattatacca aattattcct aaacaatcaa aaactccatg aatatttaaa ggttttctat
    49741 tttaaaaatc acctttgact attaatttat caaatatgtt ataatagttt tagataattt
    49801 aaggaggatt aaataatgga ttttaaacaa cttgaagtat ttgttgctgt tgcaaaacat
    49861 cagagttttt caaaggctgc aagagaactt tttttaactc aacctactgt aagcgcacac
    49921 atacagaatt tagagagaga gctagaaact gttcttataa atagaagcaa caaagttatt
    49981 acactcacaa aatctggtga aattctttat gaacatgcta tatatatatt gaataattgc
    50041 aaacgtgcaa tttatgatat aaaagaatat tcaggaaaaa tagaaggtat tatagatata
    50101 gcatgtagtt ccatacctga aacttatatt ttacctgatt ttatgaagag tttttctatg
    50161 agttatccag atgtaaaatt ttccataagc cattatgatt ctcaatatgc tatatcagaa
    50221 attttaaatg aacgaataag ctttggatta gttggttcta aaatcaataa tcctcaaata
    50281 gagtacctag acttattaga tgatgaactt gttcttatca ctccttcaga ttttaaaatt
    50341 gataataaaa ataattgtat cgatatagga gaattggctt atctaaattt tattatgaga
    50401 aaagaagggt caggtacaag aaacttaata ctaaacacac ttagtaaaaa taactttcca
    50461 gtaagtaaat taaatgtaat cgctcatgta gaatcaaatg aggctattaa ggaaatggtt
    50521 agattaggtc ttggagtgtc ctttatatcg tacatttcag ctatcgatta tctcaatgca
    50581 ggtaaaataa aatgttataa aataaaggat gttgatttta ctagaaagtt tttcttcatt
    50641 tactctaaaa agaaaacttt ttccccatta gaagataaat ttctaaacag attatgtgag
    50701 tatttcgaaa ttataatata ataactttaa taaagtagtg cttaattttg agtttataac
    50761 taattaataa gctaattata actatcacat aaatgcttat aaattattat gaaccatctt
    50821 tcttttttat ttaatttagt caaaaaatcc ctcgttcaaa tgaacttggg atttttttat
    50881 ttatactact ccaatagcag ccaatactat acaaataatc ataactgaaa ttaatatcgt
    50941 agttgtcttt accttttttc ctaataacca atacataata ccgaatatca tagctggaag
    51001 catacatggc attatttggt ctaagtaagt ttgaataggc tctgcccatt ctccactacc
    51061 tacattaaca ctaagtttta acattacatt agatgcagtc atacctccaa ttaccataag
    51121 ccctaacatt gaagctgctt ccataacttt tgaaactata cttgaaccac tcacatcttt
    51181 aaagaattga gttccatact taaatccttt atctagacat atatagcgta taataaaatg
    51241 aggaacattt attattaaaa ggaataaaat cggtcccatt atgttaccct gagaagctaa
    51301 agctatacca accccagctg ctataagctt taatgttccc cagaaaaatg aatctcctat
    51361 cccagaaact ggacccatta aacttgattt aacagcattt atactattag catcaaattc
    51421 tttattcttt gcattttctt cttccatagc tccagatata cctaccaaaa gagtacttat
    51481 atgaggagta actgacataa attctaaatg tctttttaaa gccttagatt tcttttcttt
    51541 atcatcttta tataatctac ggattattgg tgccatcatg tatgcatatg ctatattttg
    51601 catacgttcg tagttccaag atgaatctaa tgtcaatgac cttctaaaac atttccaaaa
    51661 gtctttcctc gttattttac tatctggtga aattgtctct aacttcttag aactcgttgt
    51721 catctactat tacctccttc tctcctacaa agttaacata tattaaagct attgctaatc
    51781 caaacaatgc aactcctgtt actgttatgt ttaggtaagc aaccaatata aatcctaata
    51841 ataaaaatgc tactgttttc ttattaagca tcattctagc taacatggca aaacctattg
    51901 ctggaatcac gcctgctgca acatccattc catgagttac atatgatggt ataaatgaaa
    51961 gtattttttc tattactgga acacctaatg aaaatcctat acctactatt attgctaata
    52021 ttaatttatt tcctatacca aataataatt gcacacgttc tacgccttca atattcccct
    52081 cttctgcata acggtcagca atatgagctc cccatgtaag tactactgtc attaagaagt
    52141 tatctataag caatactaga gttgctatag gaactgcaag tacaactgct gctgatacat
    52201 cttgacccgt taatattaca aacgctgtgg caataataga accagacaca aaatcaggag
    52261 gattacttgc cccaacagga aatgcaccca taaatactaa ttctaatgtt gaacctatta
    52321 ctatacctgt atgaagatta cctagtgcta aaccaacaag tggtgcaaca actataggtc
    52381 tattatgcat tgtagaacct acaaaactat gcatatatgc aaagaatgca attagagtta
    52441 tcaaaataac ttgtgtaaat tccattttca tccccctaaa attatattaa tttcattaca
    52501 tttgtagcat catcatcagg aactaattgt acaaatacat ttacgccttc tgaatctaac
    52561 tctttaatca tctttatatc atcttttgat acatgcactg ctttagatat attttcacga
    52621 ttatcatctg attttgttcc accaaggttt atagatttaa tagcttttac ctctttagca
    52681 agtctataaa catcttctac agattcacaa agtatcaata agttgtattt atcagtaaca
    52741 cctgagttaa gtgcttttat agaatctgct atgcttttca ttactaactt aacattagat
    52801 ggtttagcca ttttaagtcc tgccattctc aattcatctt ttaataagtc atcacttgct
    52861 atcaatatac agtctgtgct taaaaacttt gtccatgtaa atgctacttg tccatgtata
    52921 agtctgtggt ctactcttac taatttaatc attataattc ctccctaatt tttttgattt
    52981 catccatgaa tgtttttacg tgttctacac taacatcccc aaaatctttg taattatctt
    53041 taaagtaact tcctattatt gccatatctc ctaatttaag ctgttttttt gcattttcta
    53101 atgtaactcc agcagctata accaatggga agtctcctaa atttttacga aacagttcta
    53161 ttttttccat tgatgtttct tgacctgtag cattttctgt aactgctata gcatcacatc
    53221 ttgtcattcc tatttttaaa tcttcttcaa catcattttc tgataatact ggctgatatt
    53281 taaaacgtac gcctccaatt aaatacgctg ggcattttga acgttgtaat ttaaaaaact
    53341 cttctaaagt agcttcatct ctaggtttaa catgacctac tacagaatca acctgtatat
    53401 aactagcatt atattttgtt gccagttcaa atcccatagt atcaacattt aaacagttta
    53461 ctccatatgg tattgataaa ttagcttttg atacatattc aagtattctt tctaaatcat
    53521 aataattacc atagtaattt tctaacatta ttccatctac accattttct tcaaagattg
    53581 taatctcttt tttagctctt tcaaagatat cttctggagt atctcctttt aagtgtatca
    53641 ttgctataat tggtttttta cttttaaata ctgataatat tccctttttt ttcataaact
    53701 aaaatacctc ttcttcttct ttaatttgta atgtcacgct ttgtattcct cttctagatt
    53761 cttccactaa ttggtctata tcttcaacgg ttaattcatc agaaaacctt gtaagaagtt
    53821 ctaataccat attcaaattc attccagaaa ataacctaac attatgtaga ttagttaatc
    53881 ttaacattgc tgtacataca cttgctccat ataagtcaga taaaattata tattcacatt
    53941 ctttatcttc tgatattgtt ttttctaatt ctaaagcaaa atctgaagca ctttgtccag
    54001 ggtacaaacc atacgaactg acacaatctg ctaaatctcc tactatcatt tttactgcat
    54061 ttaaaagccc ttttgaaaag tctccatgag atgctaatat tatctttttc atactcatcc
    54121 tcctactaaa ttatagatta tatttctgct gatactgcat atttgtactt atcacttctt
    54181 ataaattgct cattgtaata taagacatca ttattttctg tatacaccga ttgtcttact
    54241 ttcaatagtg gcatattact tgcacattta agatggtcag aatattcttt gtttgaatgt
    54301 tttacttcaa atatattttc tactcgttta ggtaatgtgc ttatattatt agatataacc
    54361 tccattaaag atttatcttc taattcttct tttaataaaa acatgtaatc tattctaaaa
    54421 tagtcaactt caaaaataac aggtacttca tctattaatc taagtctttt aatacatatt
    54481 accttctctt ctagttcaat acttaaagct tcagctactt gcttatctgc tttttttatt
    54541 aaaacagaga ttattttggt acttggtttt gcattaatac gatgacaaga attagtaaaa
    54601 ctatttcctg cacatgttgc ttctattctc tctggtattg ttacataagt ccctttacca
    54661 cgttttttac ataatatatc ttcttttaca agttcattaa gtgcatttct cacagaaatt
    54721 cttatatttt atttatgttt atttatattt atttatgttt ttatgagtac atttatttac
    54781 aacctatcta aaacaatttc tttattctat tttatttata tttctttatt tgtattttat
    54841 tttattaaac tgtcatggtg gcaaaaaagg tggcaaaaat aatttgccac ctaaaataat
    54901 ctttatttat tctttctctt ttaaattttt aaaatgttct tcgagttcga ttaatttatc
    54961 ttcatccact tcatcatctt tactatgtaa cgctgatatt aaacttgaaa ttgaattctt
    55021 gtgtatgttc ttcaaaaatt cctttgtttc aaatcttaga tattttttct cttttaccat
    55081 tgcattatag tgtgtaagtt tacctatttt ctctgtactt aaaaactccc ttcgctctaa
    55141 cctttttaaa actgtgaatg tagttgattc attccattcg tatttttctt ccattgcggc
    55201 aactaattcc ttagaagtta atacatcgtt agcttcccaa atatatctca taacttttaa
    55261 ttctgcttct ggtaatttac taattttcat agtcacaccc ctttatcgaa ttatgtatat
    55321 gttaaattct atctcaataa agttttccaa acaagagaat cacactaaat attaccatcc
    55381 aattttttcc atctcgaaat tattcttcta aatttctata atattcttct aatgcgtcta
    55441 gtttttcttt acttatagac ttatgtgtag tagtaagaga acgcattatt tttctgcttt
    55501 tgctagattt taacactttt ttcttaaaag cataatattc tttgttatct attattattt
    55561 tataatgaga ttgaaacttt ataatatctc tggccaaata acctttgtca actagccttt
    55621 ttagtagtat ttttattgta cttttatgcc atctataaac ctgtctcatt tcttttacaa
    55681 tttctttttt agtcactaga gaatcttttt tccataaata ctccattact attaattctg
    55741 ctcttaataa tttttctact aatatttctt ctttcaactt atgtcactcc ttcgattgtt
    55801 ctagttcaag ttaataataa gagcttttta agacaaaaac tataggtaat ttttaccaaa
    55861 tattctactg ttttagtttg ttttcttaga agaaaaataa ctttcatatc tatagaatta
    55921 ttcaattttc aaac
//
LOCUS       DAJMZY010000013        54522 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.013, whole genome shotgun sequence.
ACCESSION   DAJMZY010000013 DAJMZY010000000
VERSION     DAJMZY010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 54522)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 54522)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54522
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.013"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            <1..1254
                     /locus_tag="OE968_000769"
     CDS             <1..1254
                     /locus_tag="OE968_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp5"
                     /protein_id="HCP7218082.1"
                     /translation="GGTAVLNKDIENKLKSNGLNVERINGKDRYETSLILANKLKDIK
                     DIKEVAVVNGEKGLSDAVSVGAPAAQNKMPIILSSPKDGVEAFDKFIRDEKVIKAYVI
                     GGTNSVSRAVEKSLPNAERVSGKDRNETNAKVIEKFYTDTNLSNLYVTKDGSKNENQL
                     IDSLAVGVLAAKNESPVVLVGNKLNTKQRDILSTKKLNTITQVGGNGNEEAFDEIKSL
                     QEKTVFEAKTVEELTDMINIASPNDIINFKPKENTVNEAFRMVTNKPITVNIKGDCSK
                     TLTVDMPNGEVNNYATLVNVIVRNIGEGGFNNHDTITILSVRDKNGRVIENTRNSDID
                     TLMILASANDTKLINDGYIGKLIDNSSNSDITNNGTIDKKVNQVEDLEAKVDSIEKAI
                     DSISQKVNKIQDILDKLGFLKKFLS"
     gene            1388..2737
                     /locus_tag="OE968_000770"
     CDS             1388..2737
                     /locus_tag="OE968_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5009 domain-containing protein"
                     /protein_id="HCP7218083.1"
                     /translation="MGIGIECNKKINKSIDKTRIKKNNLNSNSNSNSNSNSNSNSNSN
                     SNSNSNSNSNSNSNSNSNSNSNSNKISNNAVDSKLMNSRIKSIDIIRGLSIALMIVCN
                     NPGTWMRMYPQLRHAVWHGVTLADFAFPFFVISLGVTIPISINSKLKNNKSTLSIILS
                     IFKRSILLILFGFFLNYLGNPDLDTVRILGVLQRMGLVYFVTSLAYLLLKKLNVGSTA
                     TIITFLCIATFIIVGYYILAKPYGFELEGSLAQLVDLHFFKGHLYKPEFEPDGFLTSI
                     VAISSGMLGCTMGCVLLKENLGEYKKFFKILVMSIILLIGAFIFNQYFPFNKRLWSSS
                     FVLLMAGSYGILLSIFYFICDIKNKSKIFTPIIALGSSPIFTYMCLEILSHVFWNVPK
                     LTNKVDYPTTLVEWTTYELITPWAGTTWDSLIFSLLYVLFWVIVMSIMYKKKIFIKI"
     gene            2991..5015
                     /locus_tag="OE968_000771"
     CDS             2991..5015
                     /locus_tag="OE968_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HCP7218084.1"
                     /translation="MKKTTKLLATGMLSVAMVAPNVALAAENTTANTESNSDININLQ
                     RKSVVLGSKSNASVKFKEKLNADSITLNFMCYDMPLEATLNYNEKTDSYEGVINYNKD
                     PEYLNVWELQSIKINGKDEQKVLNKEDLESMGLNLKDYDVTQEFIISDANSTKAVNEY
                     MRKTSAPVKKLAGATRFETAVEISKQGWKDGSSKVVIVNGELAADGITATPLASTYDA
                     PILLANKDDIPESTKAELKRLNPSDVIIIGDDGSVSQKAVSQIKSAVNVNVTRIGGVD
                     RHETSLLIAKEIDKYHDVNKIYIANGYAGEYDALNISSKAGEDQQPIILANKDSVPQG
                     TYNWLSSQGLEEAYYIGGSQSLSSKIIDQISKIAKNGTSKNRVSGADRHETNANVIKT
                     FYPDKELSAMLVAKSDIIVDSITAGPLAAKLKAPILITPKTYVSAYHNTNLSEKTAET
                     VYQIGDGMKDSVINSIASSLSKHNAPTEPDNSGSAAGKTVVIDPGHGGSDSGATSGLN
                     GGAQEKKYTLNTALATTEYLRSKGINVVMTRDTDKTMALGERTALSNTIKPDLFTSIH
                     YNASNGAGNGVEIYYKVKDKNGGTTKTAASNILKRILEKFNMKNRGIKTRTLDNGKDY
                     LYVLRNNNYPAILVECAFIDNKSDMDKLNTAEKVKTMGTQIGIGIEDTVK"
     gene            5235..5921
                     /locus_tag="OE968_000772"
     CDS             5235..5921
                     /locus_tag="OE968_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HCP7218085.1"
                     /translation="MSGYTNDECEIPKIKSYPGADKEIASEIDYSIVKGTVLFDLYQR
                     IMDLVLSIIGLVIGLPLIAIFGILIKIEDKGPITYKQERLGKCGRRFYIYKLRSMRTD
                     AEKFGAQWAEKDDPRITKVGKFIRKTRIDEIPQLFNILKGDMGLIGPRPERPNFTVQF
                     NEEIPGFINRLAIKPGLTGWAQVNGGYEITPEEKLKEDIYYIKNRSILLDFKILFKTV
                     KVVLTGDGAR"
     gene            6016..7071
                     /locus_tag="OE968_000773"
     CDS             6016..7071
                     /locus_tag="OE968_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp7"
                     /protein_id="HCP7218086.1"
                     /translation="MIKKISTILSLVLLISISSTIGVFADANPKRELIEGSIPEISTE
                     LNKRAFKDSKEVILVNEESIVDSISATPLAYAKNAPIVVTKSKNLGRVTRNYLKELGP
                     EKVTIVGGLKAVSKDAERNIEKMGMKVERIRGKDRYDTSLKIAREMYRTVGFDEAFLL
                     SSTTGLENAISVYSYAAKSGMPIIWAKDEGFEEQIDFLKGKNLKKIYALGDSKEFIAE
                     IDSNLKNIEGIKQINKSSTNVDLIKKFYDEKDIKKIYTARLDFGSRSDVNEYISLGVV
                     SAKENMPILICSDNLSRAQDKFLKDSNINDVVEVGYTVGDYSLFKSIFNLTFLSCIVL
                     ILLLLLITFRALRYESK"
     gene            7186..8742
                     /gene="murJ"
                     /locus_tag="OE968_000774"
     CDS             7186..8742
                     /gene="murJ"
                     /locus_tag="OE968_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein biosynthesis integral membrane protein
                     MurJ"
                     /protein_id="HCP7218087.1"
                     /translation="MSKTAKAALWIMAATMFSKVLGFLRELVLANFYGTGMYADVFVL
                     TLNIPGLIIAVIGSAVATTYIPMYFETKKRLGDEGALKFTNNVLNICYIMAIVIAIIG
                     LLFTEQFVTVFAAGFRNDPAKFQAAILFTKIMISGVLFLSGSKIFSSFLQVNDSFVIP
                     GLIGIPYNIIIIAAIALSAGKNVWILPAGALLAMASQLLFQLPFAFKKSYKYKPYINL
                     KDESIKELVNLVLPMLVGVAVGQLNIFVDRLLATTLGDGKLSALNYANRLNEFVMALF
                     VTSIITVIYPKLAKMSGKDNKEGFISTIVKSSNCIILVVLPISIGAIILAEPLVRILF
                     QRGKFDALSTDLTSIALRLYSLGLLACGVRDVLYRAFYSLSDTKTPMINGSIALIINI
                     VLNLILIRPLGHAGIAISTSTSNIITVILLFISLKKKNGYFGGDKIIKTGLKSLVASG
                     VMAVATLLIYNNLYAFMGSGTIKEIISVGAGVLGGASVYTVLIVLFKVEEMDLAFEFL
                     RKGKQKLLRR"
     gene            8788..10494
                     /locus_tag="OE968_000775"
     CDS             8788..10494
                     /locus_tag="OE968_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HCP7218088.1"
                     /translation="MDYKNNYEMWLNSPYFDEQTKNELLSIKDDEKEIQDRFYKNLEF
                     GTGGLRGIIGAGTNRINIYTVRRATLGVLNYIMKTQGEEGKQKGIVIAHDSRYMSREF
                     CIEVAKTLSAYGVKAYIFEELKPTPELSFAVRYLKCAMGIVITASHNPKEYNGYKVYD
                     SDGGQICIDMANDIIAEVNKIDDYSTIKSIDFEEALSKNLITILDNEVDDEFIKAVKK
                     QVLRQNIIDEYGKKLKIIYTPIHGTGNKPVRKVLNECGFENVMVVKEQELPDSNFSTV
                     KYPNPEEKSVFNIAIEMAKNNGTDLIIGTDPDCDRVGIVVKDSSGEYVVLNGNQVGSL
                     LVRYILESLVEENKLPKNNPTIIKTIVTSELGAKIAKAYNVDCLNTLTGFKFIGEKIK
                     AFEESNDRSFIMGYEESYGYLIGTHARDKDGVVSSLMICEMAAYYSSKGMNLYEALID
                     TYNKFGYYKEDLKSVTLKGIDGIKKIKEMMLYFRSVKIDNVADVKVDKILDYKDGVDD
                     LPKSDVLKFLLEDGSWIAIRPSGTEPKIKFYFGANSDNQEDVEFKLNNLISYILNVVD
                     SI"
     gene            10516..11589
                     /locus_tag="OE968_000776"
     CDS             10516..11589
                     /locus_tag="OE968_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-1-phosphate guanylyltransferase"
                     /protein_id="HCP7218089.1"
                     /translation="MKVYNVIMAGGGGTRFWPLSRQEVPKQLINLSGEDALINETINR
                     IDSLAKKDDLFIVTNEKQLEALKDIVKDKCLDSNILPEPCARNTAAAIGFAAFNIMKK
                     YGDGVMCVYPADHYIKDEKEFKSILEKAIYIAENNDKLVTIGITPTFPSTGYGYINFN
                     RENTIEDVAYEVVEFVEKPNYEIAKEYVNSKKYVWNSGMFVWKVSKILEDFKRYLPKV
                     YEKLEDISKYLGTKEEMEKIKEIYPTIQSISIDYGIMERSNDVIVVPGDFGWNDVGSW
                     DSLGAIYPTDDEGNIKRGENITIDTKNSIIYSDDKLISTIGISDLIVVSTNDAVMVCR
                     KDKAQDVKKIVEQLKEEDRQEYM"
     gene            11601..12323
                     /locus_tag="OE968_000777"
     CDS             11601..12323
                     /locus_tag="OE968_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HCP7218090.1"
                     /translation="MIPKKIHYVWFGGPKGNIENICINSWKEKLPEYEIVEWNEKNFD
                     IEKEIKGNKFLEECYKRKLWAFISDYTRIKVLYEQGGVYMDTDMQILKDITPLLENNR
                     LVCGYEDDREYINGAIIGVEKGHPFLKDLLEYYEKEVLTSSLFTIPKIMTHLMEKNYK
                     KIDPNNYEEGIRVYDKEYFYPFGFKEDFTPECITENTFGIHWWGKSWAKKRNYFLESK
                     HLTGVNKIWKCCKIFASNTLRS"
     gene            12339..13496
                     /locus_tag="OE968_000778"
     CDS             12339..13496
                     /locus_tag="OE968_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide polymerase"
                     /protein_id="HCP7218091.1"
                     /translation="MKTLNDDRNIMIRKYLYIFVLFIILLRKYMISFIDPNMDIGMIK
                     SALFYSSIGILMLLFLFDKRKSITEMVLVGVCVLLYLLNREGAILLIVLLAVSAKQID
                     DKFIVKNYLIISACFLMVAILLFNLFPSLIFNQEVHYRYIEKIDMLVTRMDFGLGNPN
                     SVFYHMVTIYAAYIFLRYKDYNKWDRILLFGSAFFVYQTTYSRTGFFTILAGLIFVEI
                     IRWIDIKKIKGLPMLLKTLPVILTLFSVIIGTVFDKSTLLNRLLASRPKFWNVYLAEK
                     GNFLKPFGNSYSPAIKATNPLDSSYVYIISVLGVVACILFMYLMYKGIESFIEKDKKA
                     YLVALFIFLLYSFAENLLLEASFSFAVVLLIKEVILNDKREIDLWKMKSRR"
     gene            13499..14338
                     /locus_tag="OE968_000779"
     CDS             13499..14338
                     /locus_tag="OE968_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HCP7218092.1"
                     /translation="MLISLIMPTLNRYDDIYLLMDSLENQTYKNFELIVVDQNDNSKV
                     KEIVDKYIDKLDIKYIKSSKKGLSYNRNVGIDNAVGQIIGFPDDDCVYENDTLEKVIN
                     FFNKNKDYKIYSCKTMDSNKVDAFKKMYDGTCDITSSNVLDTITSITFFIDFEGKDYT
                     RFDEKLGVGGEFGAGEEIDYVLNLLSLGFKGKYFGNDIIYHPAKKHSKSKEKYQKDYN
                     YGRGFGALCKKEIVYRKNYKFAKVMVSKLVRNIGGLILSSNRDYHSATIKGRINGFRQ
                     YKL"
     gene            14353..15528
                     /locus_tag="OE968_000780"
     CDS             14353..15528
                     /locus_tag="OE968_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-glycerol glycerophosphotransferase family
                     protein"
                     /protein_id="HCP7218093.1"
                     /translation="MDKVKFLINMLLAFFIYPFNKHKFNGRDIWLIGGHSGDIYNDNS
                     KFFYEYMLKEHNDVETYWVVNKDSKVFDKIPGKKLIRGSVENYLYYYNSKAIVFSHAP
                     SADIAPYNFAVPVLNYFHKKTIKVFLNHGTISFKKRKPMNKKFKNIIDNLYKSYNIVT
                     ASSEFERNVMVNDWGMLDDSVYIIGNARYDNLPTNEVAQTRDILYTPTWRDWIKFSSG
                     KFTDTDYFKNIMNFLNDDKLNKILDEKDINVKIYMHHLMHEFIDDIKENITGKRIVFL
                     DKGVTLANEIRKSAANITDYSSVAIDFLYMNRPILFYQFDLDEYMEKVDSYIDLKSEM
                     FGSLAYNNDEAVNKLIDIIENNFEVMDNQKNERNKFFRYNDNKNCKRIYDCVLSKIK"
     gene            15557..16306
                     /locus_tag="OE968_000781"
     CDS             15557..16306
                     /locus_tag="OE968_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HCP7218094.1"
                     /translation="MKKNLVSIITPMYNSEKFIEATIKSVLNQTYQEWEMLIIDDCST
                     DNSPNIVKSYMQQDSRIKCIKTETNKGVSNARNLALSKATGQFIAFLDSDDQWNSSKL
                     EKQVNFMLENDYVISFTSYELMDENDKKLNKVIKVPPNVDYRRLLKGNILGCLTVVID
                     KSKLDFEIRMSGVRHEDYVLWLSILKKGHIAHGINEVLALYRKSSNSLSGNKIKAAMW
                     TWNIYRNIEKIPLYKAIYYFINYGINGIKKS"
     gene            16328..17236
                     /locus_tag="OE968_000782"
     CDS             16328..17236
                     /locus_tag="OE968_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HCP7218095.1"
                     /translation="MYKYKFTVFTPTYNRAHLLENLYNDLKAQTYDFNDFEWLIVDDG
                     SSDSTKELVEKFISENKLNIRYIYKENGGKHTAINLGVKNADGELFFIVDSDDGLIKD
                     SLEIANDEWDSLENKEGFSGVVGLCVYPSGDLIGTEMPEDKKICHFADLYFKYGVKGD
                     KSIVFVTDELIKFPFPERKEVRFLPESVVWNEMSKYYKVICVNKPMIIRDYLDDGLTK
                     NILSKNALRGRALEFLYLINQNTYPLSRYPYMWIKNYINLARYSLLSDSHYFGELRKV
                     SDKLLYLALFPLGYYKYIGQRKLVSK"
     gene            17284..18036
                     /locus_tag="OE968_000783"
     CDS             17284..18036
                     /locus_tag="OE968_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HCP7218096.1"
                     /translation="MNEPLVSIITPVYNSEEFLSETIKSIQNQTYKNWQLLLVDDCSK
                     DNSSEIIKSFRKEDARIKYIKLEKNSGAAVSRNVGIKNAEGRFIAFVDSDDLWDSRKL
                     EIQIEYMLKENVGFSFTSYRYMRQDGSKTNKVARAPKKIDYEGLLRNTIIGCSTVVID
                     KEIVGEFSMPLVRRGQDTATWLQLLKKEKYAYGIQEDLVNYRLVGNSISSNKIKALKR
                     TWNTYRNVENLSLPKSLYVFCFYVFNAIKKRV"
     gene            18014..19357
                     /locus_tag="OE968_000784"
     CDS             18014..19357
                     /locus_tag="OE968_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose/GDP-mannose dehydrogenase family
                     protein"
                     /protein_id="HCP7218097.1"
                     /translation="MPLKKEYKFYILGGKKMKIAIAGTGYVGLVTGVCLAEVGNENVV
                     CVDVDEQKVKSMKLGIAPIYEEGLEELMVKNYNRGRIDYTTDYKKAYEDVDVILIAVG
                     TPERSDGSANLDYIKVVAKQIAETVTKDTLVVIKSTVPIGTNEEIEDYINRNLKNDVK
                     VELASNPEFLSQGTAVKDTLHASRIVIGVESEWAREILEEIYKPFNQPIIVTNRNSAE
                     MIKYASNNFLALKISFMNDIANLCEIAGANIEDVALGMSYDDRIGSKFLKAGIGYGGS
                     CFPKDTKALHWLSEHNGYELKTVKAAIEVNESQKLKLVRKASKLVESFQDMKVAVLGL
                     TFKPDTDDIREAPSIPNIKYLLERGARVTVYDPIGVNNTKKIFGDSILYADSVDDAIE
                     DAEICFIMTEWKDVLNYDIHKYKEKMKNPLVLDGRNCYKIKDMEELGIEYYSIGR"
     gene            19363..20454
                     /locus_tag="OE968_000785"
     CDS             19363..20454
                     /locus_tag="OE968_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HCP7218098.1"
                     /translation="MKTVCYLADGSNPHTLKWCSFFKNKGYDIHVISLNGGHMEGIKI
                     YNFGSNVEELKNENISKKTGYLGSIKQIKKLVNEIKPDILHAQYASSYGFIGSLLGYH
                     PYIISVWGTDIYDFPNNGFIQKQIIKHNFRKADYIFSNSRDMAKEANKYTAKHVDVTF
                     FGVDMDRFKPMEVEKEDAFVIGIIKSLEKKYGIEYLIQAFKMLKDEYKDKKIILKIGG
                     SGSQMDNLINLAKELGIENDVQFLGRISPENVSKTFNSFDVTVFPSLREGFGVAAIES
                     EACEVPVIVTNVGGHPESVWENETGLIVEPKQPEEIKNAIIKLMENDELRLNMGKKGR
                     QFVRENYEVNLNFNDIEKIYDSIFDKYKK"
     gene            20538..22451
                     /locus_tag="OE968_000786"
     CDS             20538..22451
                     /locus_tag="OE968_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HCP7218099.1"
                     /translation="MRESIDLEKESFFNRLFKKYKFRHLTLLILDICSVLVAFRMSLS
                     LTGNLNAFTTNDIIISVCIYIVLHIVSFRLFKCYNTLWRYAGEEEIISIFVATLAYLI
                     PIYIINKLLGFDYPIMFYVLNTIFIIMFTSGARIAYRAIRIVMNKTYSRGKVSNILII
                     GAGDAGEMVIQELKRNPELKKVAVAIIDDDKNKIGRIIHNVKIVGTTSDIKDVVEKHN
                     VDEIIFSIANIEKRRKKEIIDVCKNTNCKIKTIPGIYEIIDGKVDIKQIREVEIEDLL
                     GREPIKTNLREISNYIEGKVILITGGGGSIGSELCRQIAGFNPKELIIVDNYENNAYS
                     IQQELLRKYKNKLDLKTVIASIREEKRMDEIFNKYKPEVVFHAAAHKHVPLMESSPGE
                     AIKNNIFGTLNIAGLSSKYRAKKFVLISTDKAVNPTNIMGATKRAAEMIIQTMNAESQ
                     TEFVAVRFGNVLGSNGSVIPLFKKQIEDGGPVTVTHPDIIRYFMTIPEAVGLVIQAGA
                     MAKGGEIFVLDMGEPVRILDLAKNLIKFSGFEPDVDIKIEFSGLRPGEKLYEELLMSE
                     EGLLDTEHKKIFIGRPIDVDREKITKYLKLLREITNNEEVEKIDGIMRELVPTYIKPE
                     DANIKEIATTREK"
     gene            22650..23357
                     /locus_tag="OE968_000787"
     CDS             22650..23357
                     /locus_tag="OE968_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HCP7218100.1"
                     /translation="MMNIKNKKHILKKFIAMVLIAGVVTVEAGAITASAAEPTNSPMS
                     ATVDQCDFLNVRSGASANDAVVGKINTGDKVEVLELHSNGWIKIKSVDNVTGWVNGDY
                     LTIQGGNVDAKVQNVLNLAFKQQGKPYRWGATGPNAFDCSGFTSYVYKNGAGVNLPRV
                     SRSQATVGKKVSRAELKPGDLVFFGSGGSINHVGLYVGDSKFIHSPQTGDVVKVTSMA
                     PGTNYARRLITATRVLQ"
     gene            23659..25770
                     /locus_tag="OE968_000788"
     CDS             23659..25770
                     /locus_tag="OE968_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding glycosyl-hydrolase Cwp19"
                     /protein_id="HCP7218101.1"
                     /translation="MKKISILVLSLIMTLTMCSVSSFADSSNDKEMRAAWISTVYNLD
                     WPKTKNNEAKQKKEYTDLLDKLKSVGINTAVVQVRPKSDALYKSNINPWSEYLTGTQG
                     KDPGYDPLPFLIEEAHKRGMEFHAWFNPYRITMADESIDKLPANHPAKKNPSWVVKHG
                     NKYYYDPGLPEVRKYIVDSIAEVVQNYDIDGVHFDDYFYPGVSFNDTATYQKYGKGQN
                     KDDWRRENVNTLLRDVKASIKSIKPNVVFGVSPAGIWRNKSSDPTGSDTSGNESYVGT
                     YADTRAWIKQGLIDYVVPQLYWPIGLKAADYSKLVAWWANEVKGTNVDLYIGQGIYKQ
                     GQSSYGGQNIAKEIVQQVTLNRKYSEIKGSMYFSAKDIANSTSIQKDLKSLYSSSEEP
                     VTPPSNVKVEKLRGDERYDTAVAISKKGWATNSDTVVLVNGYSIVDGITSTPLATSND
                     APILLVNKDNIPTSTKNELKRLNPSKVILIGGNNSIGDKVESEIKDTLSNVSINRVGG
                     SDRYSTSLMIAKELVKTNPVEKLYITSGTGEADSLSIASKAGEEKQPIVLVSKDNVSD
                     EVYNWISDLKVKDAYFIGGNLSISDSVINKLDKVITNDVSKNRIAGENREETNGKVIQ
                     KFYPNAEYSSMFVSKSNQLVDALTSGPLAAKLKSPVVMLGNSVTSAQKTALEPKKTTL
                     VYEAGDGINQNTLNTFLNLVK"
     gene            complement(25968..26933)
                     /locus_tag="OE968_000789"
     CDS             complement(25968..26933)
                     /locus_tag="OE968_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HCP7218102.1"
                     /translation="MSKLKKFVILLAFLVVIFPISVYGYFYYKLSAIHDSSISSDLLD
                     NNDHKNEDGIINILLMGTDARPNEDSSRSDAMMILTIDNKHNDIKLTSLARDSYVDIP
                     GHGKQKLTHAYAYGQADLLIQTIEENFNIDIQNYACVNFESFMYIIDAIGGVEVTVEK
                     GEIRELNKFIPETYKWSKSDDKGSIQYIRNSGKQTLNGYQALSFARIRHNDTAFARDG
                     RQRQIIQAIIKKTETLPVTKYPGLLDAVLPYVKTNMKPNAILSLGAQVLKMGDLNIKQ
                     FEFPIDDEIHSTGGIYGKAGWVLRFDPDTLDILHDFIFNDIEFKQ"
     gene            complement(27218..28174)
                     /locus_tag="OE968_000790"
     CDS             complement(27218..28174)
                     /locus_tag="OE968_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HCP7218103.1"
                     /translation="MSGLKKFVIFLALLVIAFPVSIYGYVFTKLKTIQDDSINTEALS
                     SNDYKNEENITNILLLGTDARPGEEVSRSDAMMILTIDNKNKSLKLTSLNRDTYVNIP
                     GHGEQKLTHAYVYGQANLLIETIEENFQLDIQNYAVVDFFSFMDIVDALGGVTVTVDK
                     SEIRELNKFIPETYKWNKNDNKGSLKYIRNSGEQKLNGYQTLAFSRIRKNDSTDERDR
                     RQRSVIQSLINGVKDLPVTKYPNLVNTILPYVKTNMNPNEIISLGKELLSIGNLNLKS
                     MEFPLSTENGRKIGNAGYVIPFEEYELDAMHDFIFKDIMVED"
     gene            28542..29330
                     /locus_tag="OE968_000791"
     CDS             28542..29330
                     /locus_tag="OE968_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HCP7218104.1"
                     /translation="MIKLIATDLDGTLLDEKSEINPEFYKVFKKLRERGIMFSAASGR
                     QYQNLIKKFEDIKDDMMFISENGTLVVYKGKEILSNPLNKELVNEIIETTRSIKGKKI
                     VMSGKKYAYIESKDEAFIQEVSTYYAKFKIVEDLTKVEGDILKIAVFDFKGAEHNNNI
                     YFEKFSDRAQVCISGVEWLDLTAKGANKGSAIKKVQKMLDIKYEETMVFGDQLNDVEM
                     MKSAYHSYAMENANEHLKQIARFRAKRNTENGVVDKIKEVIKIG"
     gene            complement(29453..29923)
                     /locus_tag="OE968_000792"
     CDS             complement(29453..29923)
                     /locus_tag="OE968_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4358 domain-containing protein"
                     /protein_id="HCP7218105.1"
                     /translation="MKKILILFFSIILSLGMVSCSSSGDYKNVSTSKIKKALKSSDLL
                     IKESKIFDAKDFNYFNDVEEDIIQGFVINSSEKLSLEDIIVIKTDEVDKIYKTLENYK
                     KDMIQAPFGEGHGEKINSEIANNTIIEKAGRYVYLISAENATQIENKILNIIKK"
     gene            30062..30706
                     /gene="uppS"
                     /locus_tag="OE968_000793"
     CDS             30062..30706
                     /gene="uppS"
                     /locus_tag="OE968_000793"
                     /EC_number="2.5.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="di-trans,poly-cis-decaprenylcistransferase"
                     /protein_id="HCP7218106.1"
                     /translation="MRIPKHVGIIPDGNRRWASQNGMTKDKGYESGIDPGLESYRLCR
                     DLGCEEVTFYGFTTDNTRRPSVQTKAFTKACIDAANILIDEGAALLVVGNTKSPMFPE
                     ELLPYTNRIKAKEGQIKANLLVNYGWYWDLNNISGVENVNKNNIQDYIQSFDVSRLDL
                     IIRWGGRRRLSGFLPVQSIYADFYVIDNYWPDFKSDDIKDAFSWYDTQDVTLGG"
     gene            30749..31654
                     /locus_tag="OE968_000794"
     CDS             30749..31654
                     /locus_tag="OE968_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HCP7218107.1"
                     /translation="MKKKLLDGKITLIICKSVKIYTKKGEEMSKGNNNNNSRNKSKKT
                     SHLNRKKRKLNKKKLAVLICFTVLFLFIAFKATQGVVALVKSMDKSNKTSQQQNVNSE
                     QFDLGNEEENKKKKYTVFIDPGHGGNDKGTESKTSNRYEKDLNLQIAKKLANKLSKQK
                     DIQVVVSRTDDTYISLKDRAILANNSSADVLVSIHLNAEKNGNTATGIETWYRNKATD
                     GSKELAQTVQSTIVSYVKVRDRGIVENNFEVLRESNMPAILIECGFLTTPSEEQKIIN
                     EKYQDQLAEGIVQGVLSYLDSKGNK"
     gene            31969..33516
                     /locus_tag="OE968_000795"
     CDS             31969..33516
                     /locus_tag="OE968_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HCP7218108.1"
                     /translation="MNKNSMTRIYSLNKIIFIIIGILGIVLLTRHIEVDIKVLILILL
                     TLFSINVFISYLKIKLYEDKINLGLINNSDKFINITKDENFLKHVQNYIISNEKENCV
                     MACFDLCRLKLINDIYGYELGDEGLNNILSNLKNYFGKEAIYGKLKSDVFVLIIKLEN
                     REQKIPYLVNLIKNKIVILSQIDSFKMDINIEASIGIYKFNNNEIDIKKAIDNADMAR
                     LKSKGLKHIEYVEFDNAMEEEIQSIMKIERDLFLAIKNKEFVIHYQPKVDSSTGNIIG
                     SEALIRWLHPSLGMVGPNKFIPIAEKNGLINNIGRWLIQEVFITINKWISEGINVLPV
                     SINLSRVELYKNDLVDFFKLMFNTYNIPKELIELEITETTALRDVKFISERLYEIKSL
                     GMNISLDDFGVGNSNFINLKGIPLDIIKIDRSLILDIVTNTKTKFMVKAIVNLSHDLN
                     VTVICEGVEDMHQVKVLSELGCNFIQGYVFFKPLDEMNYKKLLTDGSYINLKDTLLDK
                     CMTVEEE"
     gene            33519..33917
                     /locus_tag="OE968_000796"
     CDS             33519..33917
                     /locus_tag="OE968_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HCP7218109.1"
                     /translation="MISEDVDYSIRIIRAIFNNGEDKPIDAKMILKSEDIPILTLYRL
                     LRKLCANNILTFNKEDGKTYMLNVSLDTISLRTIVEVIDGKIYINKCTRYVSNCSNCL
                     KGCKVNRELLEIEKEIYKLLSRKSIRQILE"
     gene            33957..35690
                     /locus_tag="OE968_000797"
     CDS             33957..35690
                     /locus_tag="OE968_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
                     /protein_id="HCP7218110.1"
                     /translation="MDDISQDNFLLSKEYENSLDVDTKKASGIYYTPKIIVDYIVKKT
                     LKNHDIIKNPYPRILDISCGCGNFLLEVYDILYDLFEENIYELKKKYDENYWTVDNIH
                     RHILNYCIYGADIDEKAISILKDSLTNKKVVNDLDESDIKINLFCCDSLKKKWRYKFD
                     YIVGNPPYIGHKKLEKKYKKFLLEKYSEVYKDKADLYFCFYKKIIDILKQGGIGSVIT
                     PRYFLESLSGKDLREYIKSNVNVQEIVDFLGANIFKNIGVSSCILTFDKKKTKETYID
                     VFKIKNEDICINKFETLEELLKSSKFEHFNINQRLLSDEWILVNKDDETFYNKIQEKC
                     KYSLEDIAISFQGIITGCDKAFILSKDDVKLNLVDDKFLKCWIKSKNINKYIVDKSEY
                     RLIYSNDIDNENTNKRILDEIIGLYKTKLENRRECKSGIRKWYELQWGREKLFFERKK
                     IMYPYKSNENRFAIDYDNNFSSADVYSFFIKEEYLDKFSYEYLVGILNSSVYDKYFKI
                     TAKKMSKNIYDYYPNKVMKIRIFRDNNYEEIENLSKQIISILLNKSIDKGKVEKLQIK
                     MDNLIMDSLGI"
     gene            35922..37133
                     /locus_tag="OE968_000798"
     CDS             35922..37133
                     /locus_tag="OE968_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HCP7218111.1"
                     /translation="MKGLVLEGGGTKGAYQIGAYKALRELGIEFQGVTGTSIGALNGA
                     YIIQNDIEVMEDIWLNYDYTHFMNIDRETYERFKNVDFTTKNLNAVFELINKARKNEG
                     IDISPLRQLMETTLNEDIIRKSKKDFGLVTVWWDKKINPYPLYIEDIPKGRLIDYLIA
                     SSSLPIFQTNMMDDKLYLDGMFCDNMPIGLLEDKGYEDVVVIRLIDDFIGKMNLNRHQ
                     NINIKTIIPSEYLGGSLNKDRDNVEKNIRLGYLDTMKAYERCTGIKYYFDVEYKYNEE
                     YCFDKFRSMSNETIQYICNLLNIKRDASLRTVMESVIPKLGEVLGLPKDFSYKDLFYC
                     IYEKKLEENNINRIKLYDFNKVIDVVNTNIDSNRNLASNFEVRPKISIKKNKNTKLLT
                     NCIIKDIKNQS"
     gene            37326..37586
                     /locus_tag="OE968_000799"
     CDS             37326..37586
                     /locus_tag="OE968_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr family phosphocarrier protein"
                     /protein_id="HCP7218112.1"
                     /translation="MEKVVSIKNASGLHARPAGMFVKKAAEFKSTVEVVAKDKTVNAK
                     SIMGIMSLGLAQGEELKLVVNGEDEEVALAAMVELVESGFGE"
     gene            37940..39652
                     /gene="ptsP"
                     /locus_tag="OE968_000800"
     CDS             37940..39652
                     /gene="ptsP"
                     /locus_tag="OE968_000800"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HCP7218113.1"
                     /translation="MAYKGIGASPGVALGKALVVEHSELVIEKKSIDNVEAEIAKLED
                     AVAVSKEELVKVKEKASEELGAEEAEIFEAHLLVLEDPELIGSAIDKIKTESVNAEYA
                     LNEIKEMFVSMFESMDNEYMKERAADIKDVTNRILRHILGIKVVDLSALSEEVVLIAH
                     DLTPSDTATMNKKMVLGFLTDIGGRTSHTAIMSRTLEIAAIVGLNDITSKVKDGDFVV
                     FNGDTGEVIVNPDEETINKYTELKAKYEDERKALQLLKGKPSVTLDGKHVELAGNIGT
                     PNDIEGLIKNDAEGVGLYRTEFLYMDRDSFPTEEIQYEAYKAVLEGMDGKPIVIRTLD
                     IGGDKELSYLSMEPEMNPFLGYRAIRLCLDRKDIFKTQLRALYRASVHGRLRIMFPMI
                     SSLEELLQAKEVVKEVLAELDSEGVAYAKDVEIGMMIEVPSAAVISDVLAKHVDFFSI
                     GTNDLIQYTCAVDRMNQKISYLYNQFNPAVLRLIKTVIDNAHKEGKWAGMCGESAGDQ
                     KMIPILLGMGLDEFSMSPISILPARKLITSVKESDMKKLADDVLNMGTAEEIKSYIEK
                     TFNI"
     gene            39975..41525
                     /locus_tag="OE968_000801"
     CDS             39975..41525
                     /locus_tag="OE968_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HCP7218114.1"
                     /translation="MRYKKRNIDKSSELSFQSLAKYFITFYIVIILIILSMFCINTIW
                     VMKKDNQDLLSTTSNRIEDRVGETIKLLNSLSKDNYIIDNSVNGIDKSKELSMYSDEF
                     GYMMICFVDKNIIVWDEEGGNISLAGRDYMQKLFATKKYQVTDSFAAGADGKTLNYTI
                     ASPIIKNGNVDGCVFAAIYFDEIKDILKQGKGQQQQNFILFGSENQIMNLTSDETAYG
                     EKYMKLSQKTKYLGTNAKKVEKDMFNNKSGDYWAFENGKLYFMSYKPIKNTNWSLFCK
                     VNFLDIFALNLIPMGAILSVITLVFIILICMEKSFMKKRMEVIDMLLGSVQELEKRIY
                     QTERPSEVDFKEIIQLTSKGLTDGLTGVVTRTVFFDQIYNRVEMEENDKLSVISFVDL
                     DDLKCINDLYGHEIGDMVLKNVGYVLREYEIKYNGLIGRYGGDEFVMLLSGFTSREEV
                     EDLLDEIAIRLHTEVLTDDGIIQTHCSVGAVVCSVKDNKDIDNLLKQADEALYYVKRN
                     GKGNYHLV"
     gene            41551..44253
                     /locus_tag="OE968_000802"
     CDS             41551..44253
                     /locus_tag="OE968_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HCP7218115.1"
                     /translation="MKNVSKKFFVCTIIVLITFLCFSKFAIYVFDKQEKKETKVVENM
                     LNVYKNNIILNLTEKFNYSKDLTSVLVSNNYSIDKLKPIADEILKNNSCIYISVVEKY
                     NVAAFFSNSVKKDIINTPIQELNYSYSLANSIKGLVVEGPSKDQFSNGDVFLITNPIY
                     KNGEYWGEITVALDAKKVVDSFNLNKLKESGFEYELWRVHLDNGSKSTIEISTKDFNF
                     SKSHEIKFKLPTVWTLSIVYKNGWNNKNIDFIVFVILLIISILIGVMTFIYIEKKSIS
                     KELNQQSLKNLETGILNREGFLIKLQEHLNRKNNEIVLLYICITNYSKFAPVMSFEKR
                     QDYLTHIVKNLDNYIKSSHFIARISEEGFVLALEENCDKNELLNIEKGISLELLRKIK
                     VENKQVFLTIGYGSSRCVDDRKDAESLLLSAIEDYERRFPAMSPIHDFTKKCEDMLDE
                     KKQIVFGEYPDLEINKLSKVIYKYYKKVQRIMYKDYNIDIGNRRGYMRDVEVLIDYNS
                     ERMLYLFLIDICKFGKFNELFSIEIGDVILKEVSNKLKTIFSNYLYRINGDVFLGISI
                     DKESYLDTLHKVNEVFNSSLSVEDVLFDVKCNIGICQYPYHGENPYDLLEKVQIALEY
                     AKKDVKSNVKVYDKELTEEIYHENNIIKDLKKGLEEQTLEVWYQPIFNVSKNCYIKAE
                     ALIRLRNKEGGYYSAYEVITYAEKHGLIKDVGLYVLKKACDVTTKIKDKNIDFEQMQL
                     NLSAQQIVHKQCANDILSCIENCGLDKKYISVEVTEKVLMETFEIVNVTLDKLKKEGI
                     SIALDEFGSGFSSINYLANLPIENLKIDKELVEQITYSKKQFELLKTIVQITKINGMD
                     IVAEGVETKETLDLVVTSGVNLIQGHYFSEPLSEDKFIELMIEE"
     gene            complement(44759..45424)
                     /locus_tag="OE968_000803"
     CDS             complement(44759..45424)
                     /locus_tag="OE968_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218116.1"
                     /translation="MKGNIVQYNFADIEEEVYSLDYAIAWNTDEENVNIIPFTNKFCK
                     ESIESFCLGKINNFVEILNEGFVENHHYVHLDKMISVPKKKVNLVYQQDTHGYLLRDD
                     NDNLIPAKITSEQSKSISSKMELFCAGEEKCLINILLKADPSYILDVDSIKDKNILNL
                     GYESIDRYKEYNFDDDKILIFFINKKRYSVIMKKTNNSDNDLVSRNNAIKELFTNKAG
                     NLN"
     gene            45768..47198
                     /locus_tag="OE968_000804"
     CDS             45768..47198
                     /locus_tag="OE968_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4116 domain-containing protein"
                     /protein_id="HCP7218117.1"
                     /translation="MDIKNKIKSIFLPEKNDYLDDEEFEYDIENNEEDLKEDNKVHLN
                     DLSRVKYDYRELKDIENQTEEMCLLAVKQDGTIIEFVKDKTYKVCMEAVKQTYKSLKY
                     ITNQNEDICIEAVKQNYRALYYINNKTENVLIEAIKNASTYDVMEVFKFVEEQTEDVC
                     LAFIERASKNDVAEILKGIKEQTPAICLEAVKKDGKSLAYVKEQSNSICLEAVKENYS
                     ALSCVKEQTEEICIEAVKQNDFALYYVNEQTEKICMEAVKRSYMALQYVNKQTEEICL
                     EAVRIDGRALQYVKEQTEEICLESVRQNGKVLQYVKKQTENICIEAVRGSFEELEIKE
                     ILSYVKIPTERIFVEAVKQNGKILKYVENQTELICLEAVRENYNALAYVKEQTEKICL
                     EAVNQSYEALKYVKEQTEEVCLKAVKQDYRMLKYVNNQTEKICLEAVKQNYRALEFVD
                     NQTEKVCLEAVKQNRKALQYVKQKQS"
     gene            47566..48144
                     /locus_tag="OE968_000805"
     CDS             47566..48144
                     /locus_tag="OE968_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HCP7218118.1"
                     /translation="MFKRYAEKMTSVLICNNMIDNNESKVYSYGFEILIAFIVNITTM
                     LFIGFLFGKFTYVLFFLMCYCPIRQFSGGYHADNYFRCLLTFIFIILSTILIIENINI
                     DLFKNIIMIIASVSWVGICVLCPIEHRSNPISDREKLVYKKTAIFISTVVLLITILSL
                     SLSIFVDYFTYSAFAMFWIFVMLVLGKLKAKV"
     gene            48174..48320
                     /locus_tag="OE968_000806"
     CDS             48174..48320
                     /locus_tag="OE968_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic lactone autoinducer peptide"
                     /protein_id="HCP7218119.1"
                     /translation="MKKFIVRFMKFASSLALSTAILSANSTCPWIIHQPKVPKEISNL
                     KKTN"
     gene            48625..50004
                     /gene="scfB"
                     /locus_tag="OE968_000807"
     CDS             48625..50004
                     /gene="scfB"
                     /locus_tag="OE968_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioether cross-link-forming SCIFF peptide
                     maturase"
                     /protein_id="HCP7218120.1"
                     /translation="MSMIHKFSMNGYNIVLDVNGGAVHVLDDVAYDLLDFYKEKSKEE
                     ILEILKSKYQEEKINEAYEEILNLEKEGLLYTEDTYQYHPSFVHREPVVKALCLNVAH
                     DCNLKCKYCFAAQGDFGGEKELMSFEVGKAAIDYLIANSGSRKNLEIDFFGGEPLMNF
                     EVVKQLVDYGRSVEKDYNKNIRFTITTNGVLLNDEIIDYINENMHNVVLSLDGRKEVN
                     DNMRPTLNDKGSYDITLPRFKKLVEKRAKDKYYYIRGTFTRDNLDFSKDVMHFADLGF
                     KLTSVEPVVGDESNPYALREEDLPKIFEEYEKFAVEYADRQLQGDGFKFFHFMIDLNQ
                     GPCVIKRITGCGAGNEYLSVTPNGDIYPCHQFVGNEEFKMANIFDEEIVLPENLKNMF
                     REAHVYTKEECKQCWNKFYCSGGCHANAINFNNDISKPYELGCEMQRKRTECSIMIQA
                     KLMLEGATN"
     gene            50033..50530
                     /locus_tag="OE968_000808"
     CDS             50033..50530
                     /locus_tag="OE968_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HCP7218121.1"
                     /translation="MIRDYLEDKPLIDESVFVAKSADVIGNVKIGKDSSIWYNAVVRG
                     DEGPITIGENTNIQDCSIVHGDTETIIGNNVTVGHRSIVHGCKISDNVLIGMGSIILD
                     NAEIGEYTLIGAGTLITSNKKFPPGVLIMGSPGKVVRELTEEDKKYIDESYEWYLEAA
                     QNQKY"
     gene            50828..52492
                     /locus_tag="OE968_000809"
     CDS             50828..52492
                     /locus_tag="OE968_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/ABC1/UbiB kinase family protein"
                     /protein_id="HCP7218122.1"
                     /translation="MRISYRNLKRYREIGYVLIKYGFSFIVERLNIEGIAYKIPLFDP
                     PEEIKNMTTGERMKRVLEELGPTYIKIGQILSTRKDLLDQDIIDEISKLRDDVEKFDS
                     NIAIDIFKEEVGLSIEEIFLEFKEEPIAAASIGQVYEGVLKTGEEVIVKIQRPNIEKI
                     IKSDLEILRTIANTLKDLKKDFNLDLVQMIEEFQTQLMRELDYTFEAINATKFSRIFK
                     NSDEVYIPKVYSEYNTKKILVMEKVNGTKLSDVEKIRRLGYNTKTIVEIGVRSFFTQV
                     LSHGFFHADPHPGNIFVVAKNKIAYIDFGMIGIIDNKTLNQLNEIALAGVEKNVDKII
                     YLLIEMDALNGEADIKGLRQDLLYLIHYYYDISIEKINVTDILNELFRFFRQYKIVMP
                     AQFVTLAKTVITLEGTSRTLNTDFSFGSMGKEFMKHHYKSKFNPKNVVLSSRQNVEEI
                     LLDIKTIPKQLKAILKNIERNNIKMQIEDVKMTRLENCIIELTSQISLSLVLASIIVG
                     SSLIIASPNIENNIWIKFTAIAGFFISFIIGLCLVIRSIRSKYKKD"
     gene            52505..>54522
                     /gene="recJ"
                     /locus_tag="OE968_000810"
     CDS             52505..>54522
                     /gene="recJ"
                     /locus_tag="OE968_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HCP7218123.1"
                     /translation="MKKWILKYKGKIEESEFSKKLNISPEICQILKNRGICTEKDSEI
                     FMNPSLDYLRDPFLMKDMQKAVDRIKLAVEKNEKIWIYGDYDVDGVSSTSILCLYFKS
                     IGYNVDYYIPNRLEEGYGINEDAIKLISSRGCDLIISVDCGITSVSEVNTANDLGIDV
                     IITDHHECQSEIPSAFAVINPKQEDCNYPFDSLCGCGVAFKMIQALTPKEEFKTSMYN
                     YLEIVTLATICDIVPLIDENRIIVKNGLKSMKEGKNIGLRELIKVCGVESDKIGSSHI
                     GFAIGPRINASGRLGYSYLGVELFTTQSQEEAVEIASILEEKNNERQMIEAKMYHEAE
                     EMLKSNSRYNDDKVLVLAKEGWQHGIIGIVASKLTEKYYKPTILLGIENGEATGSARS
                     IKGFNIFEALIKCKDLMTKFGGHEQAAGLSLDSDNVEILANEINKFADYNLTEDDMIE
                     NVNVEFELQENVINLNLVEELHKLEPFGLNNPNPRFIVRNYILKDLKVIGKNQQHLKL
                     SIEKEKSYECIGFNMSHLKSMYKVGDKVDVLFQLDENNYMGNRKVQFLLKDIRLARPK
                     SASNDKLSLKLMSKIIPKDTQSLYNISVSDFELFDGNTDINIFDYFEKDTLIISNSIN
                     GFYRAMSDISLIDLDFNINYNIIEDDSKNTDKLELIFSPNIDKIDLKR"
BASE COUNT        21846 a         5532 c         9608 g        17536 t
ORIGIN      
        1 ggaggtactg ctgtacttaa taaagatata gagaacaagt taaaaagtaa tggacttaat
       61 gtagaaagaa ttaatggtaa ggatagatat gaaacttcac tgattttggc taataagctt
      121 aaggatataa aagatattaa ggaagttgct gtagtaaatg gtgaaaaagg attgagtgat
      181 gctgttagcg ttggggcacc agcagctcaa aataagatgc ctataatttt gtctagtcct
      241 aaggatggag tagaagcatt tgataaattt ataagggatg agaaagttat aaaagcatat
      301 gtaattggag gtacaaattc tgtttcaaga gctgtagaaa agagtcttcc taatgcagaa
      361 agagtgagtg ggaaagatag aaatgagact aatgctaaag ttatagaaaa gttttacact
      421 gatacaaatt taagtaattt atatgtaact aaggatggta gtaaaaatga gaatcaacta
      481 atagactcgt tagctgttgg cgtattggct gcaaaaaatg agtctcctgt tgttttggtt
      541 ggtaataaat taaacacaaa acaaagagat atacttagta ctaaaaaatt aaatactata
      601 acacaggtag gtggaaatgg aaatgaagaa gcttttgatg aaattaaaag tctacaagaa
      661 aaaactgtgt ttgaagcaaa aactgttgag gaattaactg atatgataaa tatagcaagt
      721 cctaatgata ttataaactt taaaccaaaa gagaatactg taaatgaagc ttttagaatg
      781 gtaacaaata aaccaataac tgtgaatata aagggtgatt gttcaaagac tcttacagta
      841 gatatgccta atggtgaagt gaataactat gctactttgg taaatgttat agttagaaat
      901 attggagaag gtggatttaa taatcatgat acaatcacta tattgtcagt tcgtgacaaa
      961 aatggtagag ttatagaaaa tactagaaat tcagatatag atacgttgat gatattagct
     1021 tctgctaatg atacaaaatt gattaatgat ggatatatag gaaaacttat agataattca
     1081 tctaatagtg atataactaa taatggtact atagataaaa aagttaatca ggttgaagat
     1141 ttagaggcta aagtagattc aattgaaaaa gctatagatt ctataagtca aaaagtcaat
     1201 aaaatacaag atatactaga taagcttgga tttctaaaga aatttcttag ctaagaatat
     1261 gtatatttaa gtgaagtgtg tgttgtaatt gttctaaagt tatgtagtta aacaggttta
     1321 tatacaaata gatttataga taaatatgta gtttagtata tatttgaata agctttgggg
     1381 aggtaacatg gggattggaa ttgaatgtaa caaaaaaata aataaaagta ttgacaaaac
     1441 tagaataaag aaaaataatc taaatagcaa tagcaatagc aatagcaata gcaatagcaa
     1501 tagcaatagc aatagcaata gcaatagcaa tagcaatagc aatagcaata gcaatagcaa
     1561 tagcaatagc aatagcaata gcaatagcaa taaaatttca aataatgctg tagattctaa
     1621 acttatgaat agtaggatta aatcaataga tataataaga gggctatcaa tagccctcat
     1681 gatagtctgc aataatcctg ggacttggat gagaatgtat cctcaattaa gacatgctgt
     1741 atggcatggt gtaacacttg cagattttgc atttcctttt tttgttatat ctttaggtgt
     1801 tacaattcca atatcaataa atagtaaact aaaaaataat aaatccacac tgagtataat
     1861 acttagtata ttcaagagaa gtatcttatt gatattattt ggatttttct taaattacct
     1921 aggaaatcct gatttagata ctgtaagaat acttggagta cttcaacgta tgggattagt
     1981 ctattttgtg actagtttag catatttact gctaaaaaaa ttaaatgttg gaagtactgc
     2041 tacaataatt acttttctat gtatagctac atttataata gttgggtact acatcttagc
     2101 aaaaccttat ggatttgagc tagaaggttc tcttgcacag ttagtggatt tacatttctt
     2161 caaaggacat ttgtacaagc cggaatttga accagatggt tttttaacta gtatagtagc
     2221 aatttcttca ggtatgttgg gatgcactat gggatgtgta cttttaaaag aaaacctagg
     2281 agaatataaa aaattcttta aaatactggt tatgagcata atcctgctaa taggtgcttt
     2341 tatctttaat cagtattttc catttaataa aagattatgg tctagctcat ttgtactttt
     2401 aatggctggc agttatggta tattactgtc aatattttat tttatatgcg acatcaaaaa
     2461 taaaagtaaa atatttaccc caataatagc acttggaagt agccccattt ttacatatat
     2521 gtgccttgag atattgagtc atgttttttg gaatgttcca aaacttacga acaaagtcga
     2581 ttatccaact accttggtag agtggactac atatgaactt ataacacctt gggcaggtac
     2641 aacttgggat tctcttatat tttctttatt gtatgtccta ttctgggtta tagtaatgtc
     2701 tataatgtac aagaaaaaaa tatttattaa aatttagtgc aatattttta gatgataaag
     2761 tctttgattt gttcaaatat acagaaacta tcaaatataa tcaaaatttc tcctcgataa
     2821 aatttaaaaa ccatgccata aaagattaca aaaagtttac aatttgtaat tttttgtgct
     2881 ataatgaaaa aagatttaca taatattgaa tttatgtaat ataaaacaag cttaagatgt
     2941 attaaaaaag atttaaagat ttaaagaacc aaaaaattag gggggatatg atgaaaaaaa
     3001 caacaaaatt attggcaaca ggaatgttgt ctgtagcaat ggtggcacca aatgtagctt
     3061 tagcggctga aaatactact gcaaatacag aatctaattc agatattaat ataaatttac
     3121 aaagaaaaag tgtagtgtta ggaagtaaat ctaatgcaag tgtaaaattt aaagaaaaat
     3181 taaatgctga ttcaataaca ttaaatttta tgtgttatga tatgccactt gaagctactt
     3241 taaattacaa tgaaaagaca gattcatatg aaggtgtaat aaactataac aaagacccag
     3301 aatacttaaa tgtatgggaa cttcaaagca taaaaataaa tggtaaagat gaacagaaag
     3361 ttttaaacaa agaagactta gagtctatgg gattaaatct taaggattat gatgttacac
     3421 aagagtttat aataagtgat gcaaattcaa caaaagcagt aaatgaatat atgagaaaaa
     3481 cttctgcacc agtaaaaaaa cttgctggag ctactagatt tgaaactgct gttgagataa
     3541 gtaaacaagg ttggaaagat gggtctagta aggttgtaat agttaatgga gaattagcag
     3601 cagatggaat tacagctact ccacttgcat ctacatatga cgcaccaata ttacttgcaa
     3661 ataaagatga tataccagaa agtacaaaag cagagttaaa acgtctaaat ccaagtgatg
     3721 taataattat aggtgatgat ggttcagttt cacaaaaggc agtgtctcaa attaaatctg
     3781 ctgtaaatgt aaatgtgact cgtattggtg gagttgatag acatgaaaca tctttactta
     3841 tagcaaaaga aatagataag tatcatgatg ttaataaaat atacatagca aatggatatg
     3901 ctggtgaata tgatgctctt aatatttcat caaaagctgg tgaagaccaa caacctataa
     3961 tattagctaa taaagattct gtaccacaag gtacatataa ttggttatct tcacaaggtt
     4021 tagaagaagc ttattacata ggtggtagtc aaagtttatc atcaaaaatt atagaccaaa
     4081 tatctaaaat agcaaaaaat ggtacttcaa aaaatagagt ttctggagca gatagacatg
     4141 aaacaaatgc aaatgtaatt aagactttct atccagataa agagttgagt gcaatgttag
     4201 ttgcaaaatc tgacataata gttgattcaa taacagcagg acctttagca gctaaattaa
     4261 aagctccaat acttataact ccaaaaactt atgtttctgc ataccataat acaaatttat
     4321 cagaaaaaac agcagaaaca gtatatcaaa ttggtgatgg aatgaaagat agtgttataa
     4381 attctatagc atctagttta tcaaaacaca atgcaccaac agaaccagat aattcaggtt
     4441 cagcagcagg aaaaactgta gtgatagacc caggtcatgg gggttctgat tcaggggcaa
     4501 caagtggatt aaatggtgga gcacaagaaa agaaatatac tcttaataca gcattagcaa
     4561 ctactgaata tttacgttca aaaggtataa atgttgttat gactagagat acagataaaa
     4621 caatggcttt aggagaaaga acagcattat caaatactat aaagccagat ttatttacaa
     4681 gtatacatta caatgcgtct aatggagctg gtaatggtgt ggaaatttat tacaaagtaa
     4741 aagataaaaa tggtggaaca actaagactg cagcatcaaa tatcttaaaa agaatactag
     4801 aaaaatttaa catgaaaaat agaggaatca agacaagaac acttgataat ggaaaagatt
     4861 acctatatgt gttaagaaat aacaattatc cagcaatact tgttgaatgt gcatttattg
     4921 acaataagag cgatatggat aagttaaata ctgcagaaaa agtaaaaaca atgggaactc
     4981 aaattggaat aggaatagaa gatacagtaa aataaaatag aaaatattaa agcaaaacat
     5041 atcatctcct gttataatgt aaaatataac aagagatgat atatttttgt aaagaatcaa
     5101 attgtttaca atgatgtttc ttgtattgat aatctgctca ttattgagta taatatagaa
     5161 ataagtcaaa aataagatag aaataagttg aaattaagaa ttaaaaaaat ttttattcca
     5221 atatggaggt aactatgtct ggatatacta atgatgagtg tgaaatacct aaaattaaaa
     5281 gctatccagg ggcagataaa gaaattgcaa gtgagattga ctatagcata gtaaaaggaa
     5341 cagttttatt cgacttgtac caaagaatta tggatttagt tttatctata ataggacttg
     5401 tgataggttt acctttaata gcaatatttg gaattcttat taaaatagag gacaaaggac
     5461 caataactta taagcaagaa agactaggaa aatgcgggag aagattctat atatataaat
     5521 tgagatctat gagaacagac gcagaaaaat ttggcgcaca atgggctgaa aaagatgatc
     5581 ctagaataac taaggttgga aagtttatta ggaaaactag aattgatgag attccacagc
     5641 tgtttaatat attaaagggg gacatgggct taataggtcc tagaccagag agaccgaact
     5701 ttactgttca atttaatgag gaaatacctg gatttatcaa caggctcgct ataaaacctg
     5761 ggcttacagg ttgggcacaa gtaaatggtg gatacgaaat cactcctgaa gaaaaactta
     5821 aagaagatat ttactatata aaaaatagga gtatattact tgactttaag atactcttta
     5881 aaactgttaa agtagtattg acaggagacg gagctagata attttaaaat attagattac
     5941 taatcaatga aaaagctctt taaaaagagc ttttttattg tcaaaaaata caaaaaagaa
     6001 aaggaatgag aacttatgat taaaaaaatt tctactatat tatcgttagt tttgttaatc
     6061 tctatttcta gtacgatagg agtatttgca gatgcaaatc ccaaaagaga attgatagaa
     6121 gggagtatac cagagatttc gacagaatta aataaaagag catttaagga ttctaaagaa
     6181 gtaattcttg taaatgaaga gtcaattgta gatagtataa gtgcaacacc tttagcatat
     6241 gcaaaaaatg ctccaatagt tgtaactaag agtaaaaatc ttggtagagt aacaagaaat
     6301 tatctaaaag aactaggtcc agagaaggtt acgatagtag gtggtttaaa ggcagtatct
     6361 aaagatgctg aacgtaatat agaaaaaatg ggaatgaaag tagaaagaat aagagggaaa
     6421 gacagatatg atacatcttt aaagatagct agagaaatgt atagaacagt aggatttgat
     6481 gaagcatttt tacttagctc aacaacagga ttagagaacg ccatatctgt atattcttat
     6541 gccgctaaaa gtggaatgcc aataatatgg gctaaagatg aagggtttga ggaacaaatt
     6601 gatttcttaa aaggcaaaaa tcttaaaaaa atatatgcat taggtgattc aaaagagttt
     6661 attgcagaga ttgattctaa cttaaaaaat atagaaggaa taaagcaaat aaataagtca
     6721 agtacaaatg ttgatttaat aaagaagttt tatgatgaaa aagatataaa gaaaatctat
     6781 actgctagat tagactttgg tagtagatct gatgtaaacg aatatatttc tttgggagta
     6841 gtatcagcaa aagaaaatat gccaatactg atttgtagtg ataacttaag tcgtgcacaa
     6901 gataaattct tgaaagatag caatataaat gatgtagttg aagttgggta tacagtaggt
     6961 gattatagtc tatttaagag catatttaat ctaacattct tatcttgtat agtattaata
     7021 ctattattac tattgattac atttagggca cttagatatg agtcgaaata gtttttgatt
     7081 tataaggaag cttttcatag gttaaattta cttaattaga ataatgttta taagcagttt
     7141 taaaagttct acttttagag tttaaattag ataaggagaa agaagatgtc aaaaacagct
     7201 aaagcagcat tgtggattat ggcagccact atgttttcaa aagtattagg tttccttaga
     7261 gaacttgtac ttgcaaattt ctatgggaca ggtatgtatg cagacgtatt tgtattaaca
     7321 ttaaatatac ctggtttaat catagcagtc ataggctctg cagttgctac aacttatata
     7381 cctatgtact ttgagacaaa gaaaagactc ggagatgaag gtgccttaaa atttactaat
     7441 aatgttttaa atatatgcta tataatggct atagtaatag ctattattgg tcttttattt
     7501 acagagcaat ttgttacagt atttgcagca ggatttagaa acgaccctgc taagttccaa
     7561 gcagcaatat tatttactaa aataatgatt tcaggagttt tattcctgag tggaagtaag
     7621 atatttagtt cgtttttaca ggtgaatgac agttttgtaa ttcctgggct tataggaatc
     7681 ccatataata ttataataat agcagcaata gcactaagtg caggtaaaaa tgtatggata
     7741 ctgccagcag gagcattatt ggctatggcg agtcagctat tgtttcaact gccatttgcg
     7801 tttaagaagt cctacaagta taagccatat ataaatttaa aggatgagtc tataaaagag
     7861 ttagtcaacc tagtattgcc tatgttggta ggagtagctg ttggacagtt aaatatattt
     7921 gttgaccgat tattggcaac cactttgggt gatggaaagt tgtctgctct taactatgca
     7981 aataggctaa atgagtttgt tatggcatta tttgttacat ctataataac agttatatat
     8041 cctaaactag caaaaatgtc tggtaaagat aataaagaag gatttataag cactattgta
     8101 aaatcttcaa attgtattat attggtggtg cttcctatat ctataggagc tattatatta
     8161 gcagagcctc ttgttagaat attattccaa aggggtaaat ttgatgcgtt atcaacagac
     8221 cttacatcta tagcgcttag attatattca ctaggtttat tggcttgtgg agtaagagat
     8281 gtcttatata gggcatttta ctctctttca gatacaaaaa caccaatgat aaatggaagt
     8341 atagctttaa taataaatat agttcttaat ttaatattga taagaccatt gggtcatgca
     8401 ggtattgcta tatcaactag tacatcaaac ataattacag ttatattatt atttatatct
     8461 cttaaaaaga aaaatggata ttttggaggg gataaaatta taaagactgg tctaaaaagt
     8521 ttggtagcat ctggtgtgat ggcagtagct actttattga tatataataa tctatatgca
     8581 tttatgggtt caggaacaat taaagaaatt atatcagttg gagctggagt attaggtgga
     8641 gcttctgtat atactgtatt gatagtttta tttaaggtag aagagatgga tttagctttt
     8701 gaatttttaa gaaaaggaaa acaaaaacta cttagaagat agataattac cttgaaattt
     8761 taaattagag tcagaaagga tgaaaatatg gattataaga ataattatga gatgtggtta
     8821 aattctcctt attttgatga acaaacgaaa aatgagctat taagtataaa agatgatgaa
     8881 aaagaaatac aagatagatt ttataaaaat ttagagtttg gaacaggtgg tttaagaggt
     8941 ataataggag cgggaactaa tagaatcaat atttatactg ttagacgtgc gacactgggc
     9001 gttttaaatt atatcatgaa aactcaagga gaagaaggta agcaaaaggg aatagttata
     9061 gcacatgata gtagatacat gtctagggag ttttgtatag aagtagcaaa gactttaagt
     9121 gcttatggtg taaaggctta tatttttgaa gaattaaagc ctacaccaga actttctttt
     9181 gctgttagat atttaaagtg tgctatggga atagtaataa cagcaagtca taatcctaaa
     9241 gaatacaatg gatataaagt atatgactca gatggtggtc aaatctgtat agatatggca
     9301 aatgatataa tagcagaagt taataagatt gatgattaca gtactattaa aagtatagat
     9361 tttgaagaag ctttatctaa aaatttaata actatattag ataatgaagt agatgatgag
     9421 tttataaaag ctgttaagaa acaagtttta agacaaaata taatagatga atacgggaaa
     9481 aaattaaaaa taatatatac acctattcat ggtacaggaa ataagccagt aagaaaagtc
     9541 ttaaatgaat gtggttttga aaatgtaatg gtagttaagg agcaagaatt gccagattct
     9601 aatttttcaa cagtaaagta tcctaatcct gaagaaaagt cagtgtttaa tatagctatt
     9661 gaaatggcaa agaataatgg cactgatttg ataataggaa cagaccctga ttgtgataga
     9721 gtaggtatcg ttgtaaaaga ttcaagtggt gaatatgtag tcttaaatgg aaatcaagtc
     9781 ggttcacttt tagttagata tatattagag agtttagttg aagaaaataa acttcctaaa
     9841 aacaatccta caataataaa aactatagtt acatcagaac taggtgcaaa aatagcaaag
     9901 gcttataatg tagattgttt aaatacttta acaggattta aatttatagg agaaaaaata
     9961 aaagcgtttg aagaaagcaa tgatagaagt tttataatgg gatatgagga aagctatggt
    10021 tacttaattg gaactcatgc tagagataag gatggtgttg tatcttcact tatgatatgt
    10081 gaaatggcag catactattc ttcaaaaggt atgaacttgt atgaagcttt gatagataca
    10141 tataataaat ttggatacta caaagaggac ttaaagtcag taactttaaa aggcatagat
    10201 ggaataaaaa aaataaaaga gatgatgctt tactttagaa gtgttaaaat agataatgtg
    10261 gctgatgtaa aagtagataa aattttagac tataaagatg gtgttgatga tttacctaag
    10321 tcagatgtac ttaaattttt acttgaagat ggctcttgga tagctataag accttcaggt
    10381 acagaaccta aaattaaatt ttactttgga gcaaattcag acaatcaaga agatgtagaa
    10441 tttaagttga acaatttaat atcttatata ttaaatgtag tggattctat ataaaaagct
    10501 aaggggagat aaacaatgaa agtatacaat gtcataatgg ctggaggagg aggaactcgt
    10561 ttctggccac ttagtagaca agaagtacct aaacagctta taaatttaag tggagaagat
    10621 gctttaataa acgaaactat aaacagaata gattctctag caaaaaaaga tgatttattt
    10681 atagtaacca atgagaagca attggaagct ttaaaggata tagtaaaaga taaatgtttg
    10741 gatagtaata tattgccaga gccatgtgcc agaaatacag cagcagctat aggctttgca
    10801 gcatttaaca taatgaaaaa atatggtgat ggtgttatgt gtgtatatcc agctgaccat
    10861 tatataaaag atgaaaaaga atttaaatct attttggaaa aagctatcta tatagcagaa
    10921 aataatgata aactagtaac tattgggata actcctacat ttccatcaac aggatatgga
    10981 tacataaatt ttaatagaga aaatactata gaagatgttg catatgaggt agtggagttt
    11041 gtagaaaaac caaactatga aattgctaaa gaatatgtaa actctaaaaa gtatgtatgg
    11101 aatagtggaa tgttcgtatg gaaggtatct aaaatactag aagattttaa gagatacttg
    11161 ccaaaagtat atgaaaaatt agaagatata agtaaatact taggaacaaa agaagaaatg
    11221 gaaaaaataa aagaaatata cccaactata caatcaatct ctatagatta tggtattatg
    11281 gaaagaagta atgatgttat agtagttcct ggtgattttg gatggaatga tgttggttct
    11341 tgggattctc taggtgcaat atatccaact gatgatgaag gtaatatcaa aagaggtgaa
    11401 aatattacta tagatactaa aaattcaatt atatattcag atgacaaatt aatatcaaca
    11461 ataggtatta gtgatttgat agtagtatct acaaatgatg cagttatggt ttgtagaaaa
    11521 gataaagctc aagatgtcaa aaaaatagta gagcagttaa aagaagaaga tagacaagaa
    11581 tatatgtagg aggtgttcat ttgattccta aaaaaataca ttatgtatgg tttggtggtc
    11641 caaaaggaaa tatagaaaat atatgtataa attcttggaa agaaaagctt ccagaatatg
    11701 agatagtaga gtggaatgaa aaaaactttg atatagagaa agaaataaaa ggaaataagt
    11761 ttttggaaga atgttataaa agaaaacttt gggcattcat atctgattat acaagaataa
    11821 aagtactcta tgaacaaggt ggagtttata tggatacaga tatgcaaata ttaaaggata
    11881 taactcctct tttagaaaat aataggctag tctgtgggta tgaagatgat agagagtata
    11941 taaatggtgc tataataggt gtagaaaaag gacatccttt tttaaaagac ttattggagt
    12001 attatgaaaa agaagtactt acttcttcat tgtttacaat accaaagata atgactcatc
    12061 ttatggaaaa gaattataag aagattgatc caaataatta tgaagaagga atacgtgttt
    12121 acgacaaaga atatttttat ccttttggat ttaaagaaga ctttacacca gaatgtataa
    12181 cagaaaacac ttttgggata cattggtggg gaaaaagttg ggctaaaaag agaaattatt
    12241 tcttagaaag caaacactta acaggtgtaa ataagatatg gaagtgttgt aaaatatttg
    12301 caagtaatac tttacgaagc taaaagggag aaagtaaaat gaagacttta aatgatgata
    12361 gaaatattat gattagaaaa tatctttata tatttgtttt gtttatcata ttacttagaa
    12421 agtatatgat atcatttatt gacccaaata tggatatagg gatgattaaa tcagcgttat
    12481 tttattcttc aataggaata ctaatgctac tttttttatt tgataagaga aaaagtataa
    12541 cagaaatggt actagttgga gtttgtgtct tactttattt attaaatagg gaaggagcta
    12601 tattattaat cgttttatta gctgtatcag ctaagcaaat agatgataaa tttatagtta
    12661 aaaattattt aataatatcg gcatgttttt taatggtagc tatattatta tttaatttat
    12721 ttccttcatt aatatttaat caggaagtcc actatagata tatagaaaaa atagatatgc
    12781 ttgttacaag aatggatttt ggacttggta atccaaatag tgtattttat catatggtta
    12841 ctatatatgc agcatatata ttcttaagat ataaagatta taataaatgg gatagaatac
    12901 ttttatttgg ttctgcattt tttgtttatc aaaccacata tagtagaact ggatttttca
    12961 ctatattagc aggattaata tttgtagaaa taataagatg gatagatata aaaaaaataa
    13021 aaggactacc aatgctccta aagacattac cggtaatact tactttattt agtgtaatta
    13081 ttggtacagt atttgataaa agcactttat taaatagatt attagcaagt agacctaagt
    13141 tctggaatgt atacttggct gaaaagggga actttctaaa accttttgga aattcatata
    13201 gtcctgctat aaaagcaact aatccattag atagttctta tgtatatata attagtgtac
    13261 taggagtagt tgcttgtata ttatttatgt atttgatgta taaaggaata gaaagcttta
    13321 tagaaaaaga taaaaaagca tatttagtag ctttatttat atttttacta tactcttttg
    13381 cagaaaattt attattagaa gcttcattta gttttgcagt agtattacta ataaaagaag
    13441 tgatattaaa tgataaaagg gaaatagatt tgtggaagat gaaaagtagg aggtagtaat
    13501 gttaatatca ttaataatgc caacattaaa tagatatgat gatatatact tacttatgga
    13561 cagcttagaa aatcaaactt acaaaaactt tgaacttata gtagtagacc aaaatgataa
    13621 tagcaaagtt aaagaaatag ttgataaata cattgataag ttagatataa agtatataaa
    13681 aagctctaaa aaaggattga gttataacag aaatgtaggc atagacaatg ctgtagggca
    13741 aattataggt ttccctgatg atgattgtgt ctacgaaaat gatacattag aaaaagttat
    13801 aaatttcttt aataaaaata aagattataa aatatacagt tgcaaaacta tggattcaaa
    13861 taaagttgat gcatttaaga aaatgtatga tggaacttgt gatatcacaa gttccaacgt
    13921 tttggatact ataacatcca taactttttt tattgatttt gaaggtaaag actatacaag
    13981 atttgatgaa aaattgggtg ttggtggaga gtttggtgct ggtgaagaga tagattatgt
    14041 tttaaactta ttgagtttag gttttaaagg aaaatacttt ggaaatgata taatttacca
    14101 tcctgcaaaa aaacattcta aatctaaaga aaagtatcaa aaagattata actatggaag
    14161 aggctttgga gcgctttgca aaaaggaaat agtctataga aaaaattata agtttgcaaa
    14221 agttatggta tcaaaacttg taagaaatat aggaggtctt atattgagtt ccaatagaga
    14281 ttatcatagt gccactataa aaggaagaat taatggattt agacagtaca agttataatg
    14341 aggatggtgt ttatggacaa ggttaaattt ttaataaata tgcttttggc tttttttata
    14401 tatccattta ataagcataa gtttaatggt agagatatct ggcttatagg tggacattca
    14461 ggggatatat acaatgataa ttcaaagttt ttttatgagt atatgctaaa agaacataat
    14521 gatgtagaaa cttattgggt agtaaataaa gacagtaaag tatttgataa aattccaggc
    14581 aaaaaattaa taagaggaag tgtagaaaac tatctgtatt attacaattc aaaagctata
    14641 gtattttcac atgcaccatc agcagatata gcaccataca attttgctgt acctgttctt
    14701 aattattttc ataaaaaaac gataaaagtg tttttaaatc atgggactat aagttttaaa
    14761 aaaagaaaac ctatgaacaa aaagttcaaa aatattatag ataacctata taaaagctat
    14821 aatatagtta cagcaagttc tgaatttgaa agaaatgtta tggtaaatga ttggggaatg
    14881 ttagatgact cagtttatat aattggaaat gcaagatatg acaatttacc aacaaatgaa
    14941 gttgcacaaa ctcgagatat attatatact cctacatgga gagattggat aaaatttagt
    15001 tcaggaaaat ttacggatac agattatttt aaaaatataa tgaatttttt aaatgatgac
    15061 aaattaaata aaatattaga tgagaaagat ataaatgtaa aaatttatat gcatcatctt
    15121 atgcatgagt ttatagatga tataaaagaa aatataacag gaaaacgaat tgtgttttta
    15181 gataaagggg taactctagc aaatgaaatc agaaaatcag ctgcaaatat aactgattat
    15241 tcaagtgtag ccatagactt tttgtatatg aatagaccta tcttgtttta ccaattcgat
    15301 ttggatgaat atatggaaaa agttgattca tatatagatt taaaaagtga aatgtttggg
    15361 tctttggctt ataataatga tgaagccgtg aataaactta ttgatattat tgaaaataat
    15421 tttgaggtta tggataacca aaaaaatgaa agaaataagt ttttcagata taatgataat
    15481 aagaactgca agaggatata tgattgtgta ttaagtaaaa ttaaataaat attttataaa
    15541 tgatgaggaa ggtaatatga agaagaattt agtatctata attactccca tgtataattc
    15601 tgaaaaattt attgaagcaa ccataaaatc agtattaaac caaacttatc aagaatggga
    15661 aatgttaatt attgatgatt gctcaacaga taatagtcct aatatagtca aatcttatat
    15721 gcaacaggat agtagaataa aatgtataaa gactgagact aataagggtg tctctaatgc
    15781 tagaaattta gcactaagta aggcaacagg acaatttata gcttttttag atagtgatga
    15841 ccaatggaat agtagtaagt tagaaaaaca agtaaatttt atgttagaaa atgactatgt
    15901 aatttcattt acttcatatg aactgatgga tgaaaatgat aaaaaattaa acaaagtaat
    15961 aaaagttcca cctaatgtag attatagaag attattaaaa ggaaatatct taggatgtct
    16021 tactgttgtg attgataagt ctaaattgga ttttgaaata agaatgagtg gtgtaagaca
    16081 tgaagattat gttttatggt tatcgatatt gaaaaaaggg catattgctc atggaataaa
    16141 tgaagttcta gcattatata gaaaatctag caattcccta agtggtaata aaataaaagc
    16201 tgctatgtgg acttggaata tatatagaaa tatagaaaaa atacctttat acaaagctat
    16261 atactacttt attaattatg gaataaacgg aatcaaaaaa agttagacag agaggaagat
    16321 ttaattaatg tataaatata aatttactgt atttactccg acgtataaca gagctcattt
    16381 acttgaaaat ttgtacaatg atttaaaagc tcaaacttat gatttcaatg attttgaatg
    16441 gttgattgtt gatgatggaa gtagcgacag tactaaagag ttagttgaaa aatttatatc
    16501 agaaaataaa ttaaatataa gatatatata caaagaaaat ggaggaaaac atactgcaat
    16561 aaatctaggt gtaaaaaatg cagatggaga gctatttttc attgtagata gtgatgatgg
    16621 tttaattaaa gattctcttg aaattgctaa tgatgagtgg gattctttag agaataaaga
    16681 aggatttagt ggagttgttg gactttgtgt atatccaagt ggagatttga tagggacaga
    16741 aatgcctgaa gataagaaaa tatgtcactt tgcagaccta tattttaagt atggcgttaa
    16801 gggagataaa agcatagtat ttgtaactga tgagcttata aaatttcctt ttccagaaag
    16861 aaaagaagtg agatttttac cagaaagtgt agtatggaat gaaatgtcta aatactataa
    16921 agttatatgt gtaaataaac ctatgataat aagagattat ttggatgatg gtttgactaa
    16981 gaatatatta agtaaaaatg cattaagagg tagagcatta gagtttttat atttaataaa
    17041 tcaaaataca tatccattaa gtagatatcc atatatgtgg ataaaaaatt acataaattt
    17101 agccagatac tcattgttgt ctgatagtca ttattttggt gaattaagaa aagtatctga
    17161 taaattgttg tatttagcat tattcccatt aggatattac aaatatattg gacaaagaaa
    17221 attagtatct aagtaaactt gttggtatag tactgctagt tgctatataa ggagagtaaa
    17281 aatatgaatg agcctttagt atcgataatt actcctgttt ataattcaga agagttttta
    17341 tcagagacga taaagtcaat ccaaaatcaa acttataaaa attggcagct tttattagtg
    17401 gatgattgtt ctaaggacaa ttcaagtgaa attataaaaa gttttcgaaa agaagatgct
    17461 agaataaaat atataaagct tgaaaaaaat tctggagctg cagtatctag aaatgttggt
    17521 attaagaatg cggaaggtcg atttattgca tttgtagata gtgatgattt atgggatagt
    17581 agaaaattag agattcagat agaatatatg ttaaaagaaa atgtaggttt ttcttttaca
    17641 tcttatagat atatgagaca agatgggtca aaaacgaata aggttgcaag agctcctaag
    17701 aaaattgact atgaaggatt acttagaaat actataatag gatgttctac agtggtcatt
    17761 gataaggaga ttgtaggaga gttcagcatg cctttggtaa gaagaggaca agatactgca
    17821 acctggttac agttacttaa aaaggaaaaa tatgcatatg ggattcaaga agatttagtg
    17881 aattacagat tagttggaaa ttctatatca agtaacaaga taaaagcatt aaaacgaact
    17941 tggaatactt atagaaatgt tgaaaattta agtttaccaa aaagtctata tgtattttgt
    18001 ttctatgttt ttaatgccat taaaaaaaga gtataagttt tatatacttg gaggtaaaaa
    18061 aatgaaaata gctatagctg ggacgggata tgtaggtttg gttacaggtg tttgtctagc
    18121 agaggtaggc aatgaaaatg tagtctgtgt tgatgtagat gaacaaaaag ttaaatcaat
    18181 gaaacttgga atagcaccta tatatgaaga aggcctagaa gaacttatgg ttaaaaatta
    18241 caacagagga agaatagatt acactacaga ctataaaaaa gcttatgaag atgtagatgt
    18301 aatattaata gctgtaggta cacctgagag aagtgatggt tcagccaacc tagattatat
    18361 aaaggtagtt gcaaagcaaa tagctgaaac tgtgacaaaa gatactctag tagtaataaa
    18421 atctacagtt ccaattggta caaatgaaga gatagaagat tatataaata gaaacctaaa
    18481 aaatgatgta aaagtagaac ttgcatctaa tccagagttt ttatcacaag gaacagcagt
    18541 aaaagatact ctacatgctt caagaatcgt tataggtgta gaaagtgaat gggctagaga
    18601 aatattagag gaaatctata agccttttaa tcaacctata atagttacaa atagaaatag
    18661 tgctgagatg ataaaatacg catcaaataa cttcttagct cttaaaatat catttatgaa
    18721 tgatattgca aatctttgtg aaatagcagg agctaacata gaagatgtag ctttaggaat
    18781 gagttatgat gatagaatag gaagtaagtt tttaaaggcg ggaataggat atggtggttc
    18841 ttgctttcca aaagacacaa aagctcttca ctggttatct gaacataatg gttatgaatt
    18901 aaaaacagta aaagctgcaa tagaagttaa tgaaagtcaa aaacttaaat tagttagaaa
    18961 ggcatctaag ttagtagaga gctttcaaga tatgaaggtt gctgttttag gtttgacttt
    19021 taagccagac actgatgata taagagaagc accatctata ccaaatataa aatatttgct
    19081 cgaaagaggg gcaagagtta ctgtatacga cccaattggt gtaaataata ctaagaaaat
    19141 atttggtgac tctatacttt atgctgattc tgtagatgat gcgatagaag atgcagagat
    19201 atgttttata atgacagaat ggaaagatgt attaaattat gatatacata agtataagga
    19261 aaagatgaaa aatcctttag tccttgatgg aagaaattgt tataaaatta aagatatgga
    19321 agagttagga attgagtatt attcgatagg aaggtaaata ttatgaagac tgtttgttat
    19381 ttagctgatg ggtcaaatcc tcatacttta aaatggtgta gtttttttaa aaataaagga
    19441 tatgacattc atgtaatctc tttaaatgga ggtcacatgg aaggaataaa aatttataat
    19501 tttggttcta atgtagaaga actaaaaaat gaaaatattt ctaaaaaaac gggatactta
    19561 ggttcaataa agcagataaa gaagctagta aatgaaataa agccagatat attgcatgca
    19621 cagtatgcaa gtagttatgg atttatagga agtctacttg ggtatcatcc atatattatt
    19681 tctgtttggg gtactgatat ttatgatttc cctaataatg gttttataca aaaacaaatt
    19741 ataaagcata actttagaaa agcagactat atcttttcaa atagtagaga tatggctaaa
    19801 gaggctaata aatatacagc taaacatgta gatgtaacct tttttggagt agatatggat
    19861 aggtttaagc ctatggaagt agaaaaagaa gacgcttttg taataggaat tataaagagt
    19921 ttagaaaaaa aatatggaat agaatattta atacaagcat ttaagatgct taaagatgaa
    19981 tataaagata agaaaataat tcttaaaata ggtggctctg gaagtcagat ggacaaccta
    20041 ataaatttag ctaaagaatt gggtatagaa aatgatgttc agtttttagg aagaatatct
    20101 ccagaaaatg taagcaagac ttttaattct tttgatgtaa ctgtatttcc ttctttaaga
    20161 gagggatttg gagtggcagc tatagaatca gaagcatgtg aagtacctgt tatagttaca
    20221 aatgtaggag gacatccaga atctgtatgg gaaaatgaaa ctggcttaat tgtagaacca
    20281 aaacaaccag aagaaataaa aaatgctata ataaaactaa tggaaaatga tgaacttaga
    20341 cttaatatgg gtaagaaagg gcgtcaattt gttagagaaa attatgaggt taatttaaac
    20401 tttaatgata tagaaaaaat ttatgattct atatttgata aatataaaaa ataaaatgaa
    20461 aaaatacagc aaaagataga tgttgttggc tatgcttagg tgcgtagctt ttgctgttta
    20521 aaggagggct tctagttatg cgagaaagta tagatttaga gaaagaaagc ttttttaata
    20581 ggctttttaa aaaatataaa tttagacatt taacactatt aattctagat atttgtagcg
    20641 tactagtagc gtttcgaatg tctttaagct tgacaggtaa tttaaatgca tttaccacta
    20701 atgatataat aatttcagtg tgtatatata tagtacttca tatagtatca tttagattgt
    20761 ttaagtgcta caacacatta tggagatatg caggagaaga agaaattata tctatttttg
    20821 tggcaacttt agcttattta attccgattt atataataaa taaattatta gggtttgatt
    20881 atcctataat gttttatgta ttaaatacaa tatttattat aatgtttaca agtggcgcaa
    20941 gaatagccta tagagctata agaatagtca tgaacaagac atattctaga ggaaaggttt
    21001 caaatatcct tataattggt gcaggagatg caggagaaat ggttatacag gaactaaaaa
    21061 gaaatccaga acttaagaaa gtagcagtgg ctataattga tgatgataaa aataaaattg
    21121 gaagaataat ccataatgtg aaaattgtag gaacaacttc agatataaaa gatgtggtag
    21181 aaaagcacaa tgtagatgag ataatctttt caatagcaaa catagagaaa cgtagaaaaa
    21241 aagagattat tgatgtatgt aaaaacacta actgtaaaat aaagacaata ccaggaattt
    21301 acgaaattat agatggaaaa gttgatataa aacagattag agaagtagag atagaagact
    21361 tgttgggtag agagcctata aaaacaaatt taagagagat aagtaattac attgagggaa
    21421 aagtaatcct aataactgga ggaggaggct caattggttc agagctttgt agacagattg
    21481 caggatttaa tcctaaagag cttattatag ttgataatta tgaaaataat gcttactcaa
    21541 tacaacaaga attacttaga aaatataaaa ataaattaga tttaaagaca gtaatagcat
    21601 caataagaga agaaaaaaga atggatgaaa tatttaataa atataaacca gaagtggtat
    21661 ttcatgcagc agcacataaa catgttcctc ttatggaatc gagccctggc gaagctataa
    21721 agaataatat atttggaact ttaaacatag ctggcttgtc ttcaaaatat agagctaaga
    21781 aatttgtcct tatatctaca gataaggctg taaaccctac taacataatg ggagctacta
    21841 aaagagctgc tgaaatgatt atacagacta tgaatgctga aagccagact gaatttgttg
    21901 ctgttagatt tggaaatgtg cttggtagta atggtagtgt aattccactt tttaagaagc
    21961 aaattgaaga tggcggacca gtgacagtta ctcatccaga tattattaga tattttatga
    22021 caataccaga agcagtaggc ttagtcatac aagctggggc tatggctaaa ggtggagaaa
    22081 tatttgtact tgatatggga gaacctgtaa gaatattgga tttagcaaaa aacttaatta
    22141 aattcagtgg atttgagcca gatgttgata taaaaattga attttctggt cttagaccag
    22201 gagaaaagtt atatgaagaa ctacttatgt cagaagaagg tctgttggat acagagcata
    22261 aaaagatttt tattggtaga ccaatagatg ttgatagaga aaaaataaca aaatacttaa
    22321 aacttttaag agaaattact aacaatgaag aggttgaaaa aatagatggt attatgaggg
    22381 aattagtgcc aacttatatt aaaccagaag atgctaatat caaagaaatt gcaacaacta
    22441 gagaaaagta gaatatattt ctaatttgta accaggggga gcaaaaagaa acaaatatat
    22501 actaaaaaga aacaaaagat tacaaaaaga ttacaaaaag attacaaaaa aggttgcaat
    22561 ttattttgat gtaagataga atgttaatta ggaattggaa acgaaggaac aaaatgttaa
    22621 attttcgaaa ggattaggta tttgagatta tgatgaatat taaaaataaa aaacatatat
    22681 tgaaaaaatt tatagctatg gtgttaatag caggagttgt cacagtagaa gcaggagcaa
    22741 taacggctag tgcagcagag ccaactaatt cacctatgag tgcaacagta gaccagtgtg
    22801 attttttaaa tgtaagaagt ggagctagtg caaatgatgc agtagtagga aagataaaca
    22861 caggagacaa agttgaagtt ttagaattac attcaaatgg atggattaaa ataaaaagtg
    22921 ttgacaatgt tacaggatgg gtaaatggag attatttaac tattcaaggt ggaaatgtag
    22981 atgcaaaggt acaaaatgtt ttaaacttag catttaagca acaaggtaag ccatatagat
    23041 ggggagcaac tggaccaaat gcttttgatt gttctgggtt cacttcttat gtctataaaa
    23101 atggagcagg agttaattta ccaagagtat caagatcaca agcaacagta ggaaagaaag
    23161 tatcaagagc agaattaaaa ccaggagatt tagttttctt tggttcaggt ggttcaataa
    23221 atcacgttgg attgtatgta ggagattcta aattcataca ttcaccacaa acaggagatg
    23281 tagtaaaagt tactagcatg gctccaggaa ctaattatgc aagaagactt ataactgcta
    23341 cacgtgtttt acaataataa tagatattga tttacatagg attgaatatt aacattaaat
    23401 atataattac atttaatgtt ttacatagag atttaagagt ttagtaatat taaaatagtg
    23461 atgaacgtta taaaaacagc aaagaagata aatttctttg ctgttttttt tataataaat
    23521 tatttcatat tataatcaaa tatcaaatat aaattttaac tatattattc aatatttgac
    23581 agataatatg aattttagat atacttaata agaagtatat tgtagaaaaa ataaatttaa
    23641 aaaattaagg gggatgaaat gaaaaaaata agtatattag tattatcatt gataatgaca
    23701 cttactatgt gtagtgtaag ttcatttgct gattcatcaa atgataaaga aatgagagct
    23761 gcttggatat ctacagttta taatttagac tggcctaaga ctaagaataa tgaagccaag
    23821 caaaaaaagg aatacacaga tttattggac aaattaaaaa gtgtaggaat aaatacagca
    23881 gtggttcaag taagaccaaa atcagatgct ttatataaat caaatataaa cccatggtct
    23941 gaatatctta ccggtacaca aggtaaagac cctggatatg acccattacc atttttaata
    24001 gaagaagcac ataaaagagg aatggaattt catgcatggt ttaatccata tagaataact
    24061 atggcagatg agagcataga taaattgcca gcaaaccatc cagcaaagaa aaatccaagc
    24121 tgggtagtta aacatggaaa taagtattac tacgacccag gtttaccaga agttagaaag
    24181 tacatagtgg atagtatagc agaagtagtt caaaattacg atatagatgg agttcatttt
    24241 gatgattact tctatccagg agtaagtttc aatgatactg caacatacca aaaatatgga
    24301 aaaggacaaa ataaggatga ttggagaaga gaaaatgtaa atactctact tagagatgta
    24361 aaagcgtcta taaagagtat aaagcctaat gttgtatttg gtgtaagccc agcaggtata
    24421 tggagaaata agagtagtga cccaacaggt tcagatacat caggtaatga aagttatgta
    24481 ggtacatatg cagatacaag agcatggata aaacaaggat tgattgacta tgtagttcca
    24541 caactttact ggccaattgg tcttaaagca gcagattatt ctaaattagt ggcatggtgg
    24601 gctaatgaag taaaaggaac aaatgtagac ttatacatag gacaaggtat atataagcaa
    24661 ggtcaatcga gttatggtgg acaaaatata gcaaaagaaa tagtacaaca agtaacatta
    24721 aatagaaagt atagtgaaat aaaaggtagt atgtatttct cagctaaaga tatagcaaat
    24781 agtacttcta tacaaaagga tttaaagagt ttatattcta gtagtgaaga accagttact
    24841 ccaccatcta atgttaaagt ggagaaatta agaggcgacg aaagatatga cacagcagta
    24901 gcaataagta aaaaaggttg ggctacaaat tcagatacag tagtattagt aaatgggtac
    24961 tctatagttg atggtataac atcaacacca cttgctacat caaatgatgc tcctatacta
    25021 ttggtaaata aggataatat acctacatcc actaagaatg agttaaaaag acttaatcca
    25081 agtaaagtta ttttaattgg aggaaataac tctattggag ataaagttga gagtgagata
    25141 aaagatacat tgtcaaatgt atcaataaat agagttggtg gttcagatag atatagtaca
    25201 tctttaatga tagcaaaaga attagtaaaa actaatccag tagaaaaact atatataaca
    25261 agtggtacag gtgaagcaga ttctctttct atagcttcaa aagcaggaga agaaaagcaa
    25321 ccaatagtat tagtatcaaa agataatgta agtgatgaag tttacaattg gatatcagat
    25381 ttaaaagtaa aagatgctta ttttataggt ggtaatctaa gtatatctga ttcagtaata
    25441 aataagctgg ataaggtcat tacaaatgat gtatctaaaa atagaatagc tggagaaaat
    25501 agagaagaaa caaatggaaa agtaatacaa aaattctatc caaatgctga atattcatca
    25561 atgtttgtaa gtaaaagtaa tcaattggta gatgcattaa catcaggtcc tttagcggct
    25621 aaattaaaat caccagtagt tatgcttgga aatagtgtaa catctgctca gaaaactgct
    25681 ttagagccta agaaaactac tctagtatac gaagctggag atggtataaa tcaaaacaca
    25741 ttaaacactt tcttaaactt agttaagtaa taaaaaagtt aatttaaaat acagagtatt
    25801 ttacaaatgt agattaaaat gaaaattatc atgataaatt agaaaataaa aaagaactat
    25861 atgcattttg taatcaagtg tacacagcaa cttgaaaata attatgcgat atagttcttt
    25921 tttagtaatt aatcttatac tttttaataa actttatgtt gaatttttta ttgtttaaac
    25981 tctatgtcat taaatataaa atcgtgtaat atgtctaaag tatctgggtc aaatctaaga
    26041 acccatccag cttttccata tataccacct gtactatgaa tttcatcatc aataggaaat
    26101 tcaaattgct taatatttaa gtcacccatt tttaaaactt gagctcctaa agaaagtatt
    26161 gcattaggct tcatgttagt tttaacatat ggaagaactg catctaataa acctggatat
    26221 ttagtaacag gtaaagtttc cgttttcttg attatagctt gtataatctg tctctgtctg
    26281 ccatctctag caaaggctgt atcgttgtgt ctgatacgtg caaaagatag tgcctgatat
    26341 ccatttagag tctgctttcc agagtttcta atgtattgta tgctaccttt atcatcactt
    26401 ttactccatt tataagtttc aggaataaat ttatttagtt ctcgtatttc tcctttttca
    26461 acagtaacct caacgccacc aatagcatca attatataca taaatgattc gaaattaaca
    26521 caagcataat tttgaatatc aatattaaaa ttctcttcaa ttgtttgtat taataaatca
    26581 gcttgtccat aagcataagc atgagtaagt ttttgtttac catgaccagg gatgtctaca
    26641 tagctatcac gagctaatga tgtaagtttg atatcattgt gtttgttatc aatagtaagt
    26701 atcatcatag catctgacct tgaagaatct tcatttggtc tagcatctgt tcccataagt
    26761 agtatgttaa ttatcccatc ttcattttta tggtcattgt tatccaataa atcactactt
    26821 atgctcgagt catgaatagc agataattta taataaaaat atccatagac acttataggg
    26881 aatattacta ccaagaaagc cagtagtata acaaatttct ttaattttga caaaagtacc
    26941 ccttctttct tctttttcct gtatattttt taatagcata cacttaatta tattaaagta
    27001 ttgagatata ttcaatactt gtttcagtta caaaaaaaag acaatgatat aatttataag
    27061 aaaatttatc gacctatata tatagttaaa agtatatata atatattttt taaaagtaat
    27121 ttatatttta aaataaaaac acaccccata aatacaaagt aatttgcatt taagaggtat
    27181 gtatttatca tcaaattatt ggtttgtttt ggaatttcta atcttcaacc ataatatctt
    27241 taaatatgaa atcatgcatt gcatctagtt catattcctc aaaaggtatt acatagcctg
    27301 cattacctat ttttctacca ttttcagtag aaagaggaaa ctccatagat ttcaaattta
    27361 aatttcctat acttaaaagt tcttttccta aagatattat ttcattagga ttcatattag
    27421 tttttacata cggaagtatt gtgttaacta gattaggata tttagtgact ggtaaatcct
    27481 taacaccatt tattaaactc tgtataacac ttctttgtct tctatctctt tcatctgtac
    27541 tatcattttt tcttatacga gaaaatgcaa gtgtctgata tccatttaat ttttgctcac
    27601 cagaatttct tatatattta agagaacctt tattgtcatt tttattccat ttataagttt
    27661 caggaataaa tttatttaat tctcttattt cactcttatc aacagtaaca gtaactccac
    27721 ctaaagcatc aactatatcc ataaaagaga aaaagtcaac tacggcgtag ttttgtatat
    27781 caagttggaa gttttcttct atagtttcta ttaataagtt agcttgtcca tatacgtagg
    27841 catgtgttaa tttttgttct ccatgtcctg gtatattaac ataagtatct ctatttaatg
    27901 aagttagctt aagactttta tttttattat caatagtaag tatcatcatg gcatcagaac
    27961 gagaaacttc ttctcctggt cttgcatctg tacctaacaa taatatgttt gtgatatttt
    28021 cttcgttttt atagtcatta ctactaagcg cctctgtatt tatactatca tcttgtatag
    28081 tttttaattt agtaaaaaca tatccatata tactaacagg aaatgctata actaaaaggg
    28141 ctagaaatat aacgaacttt ttgagtcctg acaataatat cccctacttt ctaaattttt
    28201 taattacaca tagttaatta tattaaaaat ttgttacata agcaataaaa aacacaataa
    28261 attagcataa gtttgtcata atataattat ttttatagca ttttatagaa gaaagtgtgt
    28321 agttattatt gattttattg gaatataatt gtatgaagac ttaaattttt ataaactaat
    28381 gtgtatattg aaaaaaatat tttcctgaat gtagttatag catcttatga aaggtgcaaa
    28441 ttgtaattta aaatttttag tgtataataa gaattgaaaa ttcaaaccga taaaaattaa
    28501 taaaaaataa ttataaatta ataatttggg ggaggaaatg tatgataaaa ttaatagcaa
    28561 cagatttaga tggaactttg ttagatgaaa agagcgaaat aaatccagag ttttataaag
    28621 tatttaaaaa attaagagag agagggataa tgttttctgc tgctagtggc aggcagtatc
    28681 aaaatctgat aaaaaaattt gaagatataa aagatgatat gatgtttata tcagaaaatg
    28741 gaacactagt agtatataaa ggaaaagaaa tattatcaaa tcctttaaat aaagaattag
    28801 taaatgaaat catagagaca acaagaagta taaaagggaa aaaaattgta atgagtggga
    28861 aaaaatacgc ttatatagaa agcaaagatg aagcgtttat acaagaggtt agtacttatt
    28921 atgcaaagtt taaaattgta gaagatttga cgaaagtaga gggagacata ttgaagatag
    28981 ctgtgtttga cttcaaaggt gcagaacata ataataatat ctactttgaa aagttttctg
    29041 atagagctca agtatgtatt tctggagtgg agtggcttga tttaactgca aaaggtgcaa
    29101 ataaagggag tgccataaaa aaagtacaaa aaatgttaga tataaaatat gaagaaacta
    29161 tggtatttgg tgaccagtta aatgatgtgg aaatgatgaa aagtgcctat catagttatg
    29221 ccatggaaaa tgcaaatgaa catttgaaac aaattgctag atttagagca aaaagaaata
    29281 ctgaaaatgg cgttgtagat aagataaaag aggttataaa aattggatag tcatatgtat
    29341 agatgaaaaa gattattttg aagaaatcaa aaaaatatca atgtaatttt gataaataag
    29401 tttatttatg cgaaaattac attgatattt aataaacatc aataatagat atttattttt
    29461 ttatgatatt cagtattttg ttttctattt gagttgcatt ttcagcagaa attaaataaa
    29521 catacctacc tgccttctca attatagtat tatttgctat ttcagaattg attttttctc
    29581 catgtccttc tccaaaaggt gcttgtatca tatctttttt ataattttct agagttttat
    29641 agattttatc tacctcgtca gtttttataa cgataatatc ttctagagat aatttttcag
    29701 aagaattaat tacaaaacct tgaattatgt cttcctctac atcattaaaa tagttaaaat
    29761 cctttgcatc aaagattttt gattccttta taagtaaatc agaagatttt aatgcttttt
    29821 ttatttttga tgtagaaacg tttttgtaat caccacttga agaacaacta accattccta
    29881 atgataagat tatcgaaaaa aacaatatta aaattttttt catgataaac ctccaagttt
    29941 tttaaactct gtcttaaatt agtttactac ataattatat aaaaataaat gtatttaatg
    30001 ttacagtttt gattaataat gtaatatttt gataataata cctattgaga ggtgattaga
    30061 aatgagaata ccaaaacatg taggaattat accggatgga aatagaaggt gggcaagtca
    30121 aaatggtatg acaaaagata aaggatatga aagtggaata gaccctggac tagagtctta
    30181 tagattatgt agagatttag gctgtgaaga ggtgactttt tatggattta caactgataa
    30241 tacaagacgt ccatcagtgc agacaaaagc ttttacaaaa gcatgtattg atgctgcaaa
    30301 tatattaata gatgaaggtg ctgctttatt agttgtagga aatacaaaat cgccaatgtt
    30361 tccagaagaa ttattaccat atactaatag aattaaagcc aaagaaggtc aaataaaagc
    30421 aaatcttctg gtaaattatg gttggtattg ggacttaaat aatatatcag gagtagaaaa
    30481 tgtaaataaa aataatatac aggattacat acagtcattt gatgtatcca gactagactt
    30541 gataatcaga tggggtggaa gaaggagatt aagtggtttc cttcctgtac aatcaattta
    30601 tgcagatttt tatgttatag ataattattg gccagatttt aagagtgacg atataaagga
    30661 cgcatttagt tggtatgata cacaagatgt cactttaggt ggataattaa aaatattctg
    30721 atttaaggtt gtagagtgtt ttaaattatt gaaaaaaaaa cttcttgatg gtaaaataac
    30781 actaataata tgtaaaagtg taaaaattta taccaagaag ggtgaagaaa tgtcaaaagg
    30841 caataataac aataattcaa gaaacaaatc taaaaagacc agtcatctga atagaaaaaa
    30901 gcgaaaatta aataagaaaa agttagcagt gttgatttgc tttacagttt tatttttatt
    30961 tattgcattt aaggctactc aaggtgtagt agctttggta aaaagtatgg ataaaagtaa
    31021 taaaactagt caacaacaaa atgttaactc agaacaattt gaccttggta atgaagagga
    31081 aaataaaaag aaaaaatata ctgtatttat agacccaggt catggaggca atgataaagg
    31141 aactgaaagc aagaccagta atagatatga aaaagaccta aatctacaaa ttgcaaaaaa
    31201 attagcaaat aaattatcta aacaaaagga tattcaagta gtagtatcca gaactgatga
    31261 tacatatata tcattaaagg atagagctat cttagcaaat aatagttctg ctgatgtgct
    31321 tgtttctatt catttaaatg cagagaaaaa tggtaataca gcaacaggta tagaaacttg
    31381 gtataggaat aaagctacag atggttcaaa agaacttgca cagacagtac aaagtactat
    31441 agtatcctat gttaaagtta gagatagggg aatagttgaa aataactttg aagtacttag
    31501 agaatcaaat atgcctgcta tattaataga gtgtggtttt ttaacaacac cttcagagga
    31561 acaaaaaata ataaatgaaa aatatcaaga ccaacttgcg gaaggaattg ttcaaggtgt
    31621 actttcatac ctagattcta aagggaataa gtaaattaac tttactttaa tgtgaggata
    31681 aatttaaaag tttaactgtg taaattgtat taactttatt tcgtaatgtt ggaaatattg
    31741 tttgaattta gaaactatga aattagaaat tattttatct atatctaatt tcatagtttt
    31801 ttttgcaaaa aatttatagt tataaaattt taaaaaataa atttagtata atgtaatgta
    31861 gttatttata tgtgatttta acttgcattg atttgctatc aattgtgctt tataattagt
    31921 atatataaag tttaactgta agataattta aaaaataggg gaatttatat gaataaaaat
    31981 agcatgacaa gaatttacag tttaaataaa ataattttta ttataattgg aattttagga
    32041 atagttttac tcacaagaca tattgaggta gatattaaag ttttaatttt aattttatta
    32101 accttgttta gtataaatgt atttatttca tatcttaaaa ttaagttgta tgaggataaa
    32161 attaatttag gattgataaa taattcagat aagtttataa atattactaa agatgagaac
    32221 ttcctaaaac atgttcaaaa ttatattatc agtaatgaaa aagaaaactg tgtaatggct
    32281 tgttttgatt tatgtagact caaacttata aatgatatat atggttatga gctaggggat
    32341 gaagggttaa ataatatttt aagtaactta aaaaattatt ttggaaaaga agctatttat
    32401 ggaaagttaa aaagtgatgt ttttgtatta ataataaagc ttgaaaatag ggaacagaag
    32461 attccttatt tagtaaatct tattaagaat aaaattgtga tactaagtca gattgacagt
    32521 tttaaaatgg atataaatat tgaggcttct attggaattt ataaatttaa caataatgaa
    32581 attgatataa aaaaagctat agataatgct gatatggcaa ggcttaaatc aaaaggacta
    32641 aagcacatag agtatgtaga atttgataat gctatggaag aagaaataca atcaattatg
    32701 aaaatagaga gagatttatt cttggctatt aaaaataaag agtttgtaat tcactatcaa
    32761 cctaaagttg attcaagtac aggtaacatt ataggttcag aggcattgat aagatggttg
    32821 cacccatcat taggcatggt tggaccaaat aagtttatac ctatagctga aaaaaatggt
    32881 ctgataaaca atattggtag atggctaatt caagaagttt ttattaccat taacaagtgg
    32941 atttcagaag gtataaatgt cttaccagtc tcaataaatc tttctagagt agaactatat
    33001 aaaaatgatt tagttgattt ttttaaactg atgtttaata catataatat tccaaaagaa
    33061 cttatagaat tagaaattac agaaacgaca gcactaagag atgtaaaatt tataagtgaa
    33121 aggctttatg agattaaatc tttaggtatg aatatatcat tagatgattt tggagtaggt
    33181 aattcaaatt ttatcaacct taaggggata ccactagata ttataaaaat tgataggtca
    33241 cttatattgg atatagttac aaatacaaaa acaaagttta tggtgaaagc aattgttaac
    33301 ctttcacatg atttaaacgt aactgttata tgtgaagggg tagaggatat gcatcaggtc
    33361 aaagtcttaa gtgaactggg atgtaatttc atacaaggtt atgtattttt taaacctttg
    33421 gatgagatga attataaaaa acttcttact gacggaagtt atataaatct gaaagatact
    33481 cttttagata aatgcatgac agttgaggag gagtaaggat gatttcagaa gatgtagatt
    33541 attcaataag aatcataaga gctatattta ataatggaga agataaacca atagatgcta
    33601 aaatgatatt aaaaagtgaa gatataccaa tactaacact atacagactg cttagaaagc
    33661 tttgtgcaaa caatattctt acttttaaca aagaagatgg caagacatac atgttaaatg
    33721 tgtcattgga tacaataagt ctaagaacta ttgtagaagt aattgatgga aaaatatata
    33781 taaataaatg tacgagatat gtatctaatt gcagtaattg cttaaaaggt tgtaaagtaa
    33841 atcgtgaatt gctagaaata gaaaaagaaa tttataaact tttatcgaga aaatctataa
    33901 gacaaatact agaataaaaa attttcagct atgataataa ttggaggttt tcggttatgg
    33961 atgatatatc tcaagataat tttctactgt ctaaagagta tgagaatagc ttagatgtag
    34021 atactaaaaa agcaagtgga atatattata ctcctaaaat aattgtagat tatattgtga
    34081 aaaaaacttt aaaaaatcac gatataatta aaaatccata tccacgaata cttgatattt
    34141 cctgtgggtg tggaaatttt cttttagaag tatatgatat tttatatgac ttatttgagg
    34201 aaaatatata tgaattgaaa aagaagtatg atgaaaatta ttggactgtt gataacatac
    34261 accgtcatat attaaactat tgtatatatg gtgctgatat tgatgaaaaa gctataagta
    34321 tattaaaaga tagcttaaca aataaaaagg tagtaaatga tttagatgaa tctgatataa
    34381 agattaatct attttgttgt gatagtctta aaaagaaatg gcgatataag tttgattaca
    34441 tagtgggtaa tccaccctat attggtcata aaaaacttga aaagaaatat aaaaaatttc
    34501 tcctagaaaa atatagtgaa gtttataagg ataaagctga cttatatttt tgtttttata
    34561 aaaagattat agatatttta aagcaaggag ggattggcag tgttataact ccaagatatt
    34621 ttttagaaag tctatcaggt aaagatttaa gagaatatat taaatcaaat gtcaatgttc
    34681 aagaaatagt ggatttttta ggtgcaaata tatttaaaaa tataggggta tctagttgta
    34741 ttctaacttt tgataagaaa aaaacaaaag agacatatat agatgtattt aaaatcaaaa
    34801 atgaggatat atgtataaat aaatttgaaa cattggaaga acttctaaag agtagcaaat
    34861 ttgaacattt taatataaat cagagattgc tatctgacga atggatactt gtaaataaag
    34921 atgatgaaac tttttataat aagatacaag aaaaatgtaa atatagcttg gaagatatag
    34981 caataagttt tcaaggaata attacagggt gtgataaagc gtttatttta agtaaagatg
    35041 atgtaaagtt gaaccttgta gatgataaat ttttaaaatg ttggataaaa agtaagaata
    35101 taaataaata tatagtagat aaaagtgaat ataggctaat atactcaaat gatatagata
    35161 atgagaatac aaataaaagg atactagatg aaattatagg gctatataaa acaaaattag
    35221 aaaacagaag agaatgtaaa agtggaataa ggaaatggta tgaacttcaa tggggtagag
    35281 aaaagctttt ctttgaaaga aaaaagataa tgtatcctta taaatcaaat gaaaatagat
    35341 ttgctataga ttatgataat aatttttcaa gtgcagacgt atattctttt tttataaaag
    35401 aagagtattt agataaattt tcatatgaat atctagttgg aattttaaat tccagtgttt
    35461 atgataaata ctttaaaata actgctaaaa aaatgagtaa aaatatatat gattactatc
    35521 ctaataaggt tatgaagata aggattttta gggataataa ttatgaagag atagagaatt
    35581 tatcaaagca aataatatca attttattaa ataagtctat agataaagga aaagtagaaa
    35641 aattgcagat aaaaatggat aacttgataa tggattcttt aggtatataa gcagttgtaa
    35701 gtattaaaaa attataatct tttaattgtt tatttaaatt tagaaataaa aagttagcca
    35761 tataaaaaat attaaaaata tatacttttc aatatttttt tgataaaata agaatgaatt
    35821 tgtgcaattt tatttttctc caataactaa aaatagtttt ttgaattaat atttgcttaa
    35881 gaataaaaat cagaaacgtt tttgatatag taggtgataa tatgaaagga ttagttttag
    35941 aaggtggagg aacaaaagga gcctaccaaa taggtgcata taaagcttta agagagcttg
    36001 gtatagagtt tcaaggagta actggcacat caattggtgc tttaaatgga gcatatataa
    36061 ttcaaaatga tattgaagta atggaagata tttggttaaa ttatgactat actcatttta
    36121 tgaatattga tagagaaacc tatgagaggt ttaaaaatgt agatttcact actaaaaatc
    36181 tcaatgcagt gtttgagctt ataaataaag ctagaaaaaa tgaaggtata gatataagcc
    36241 cattaagaca attaatggag acaacattaa atgaagacat aataaggaaa tcaaaaaaag
    36301 actttggact tgttacggtc tggtgggata aaaaaattaa tccatatcca ttgtatatcg
    36361 aagatatacc taaaggaaga ttgattgatt atttaattgc tagttccagt ttgcctattt
    36421 ttcaaacgaa catgatggat gataagttgt atcttgatgg aatgttttgt gataacatgc
    36481 caataggact cttggaagac aaaggttatg aagatgttgt tgtaattagg ttgattgatg
    36541 attttattgg gaaaatgaat ctaaatcgac atcaaaatat aaatataaaa actataatac
    36601 catcagaata tctaggaggt tctcttaata aagatagaga taatgtagaa aaaaacatcc
    36661 gactaggtta cttagatact atgaaagcat atgaaagatg cactggaatt aagtattatt
    36721 ttgatgtaga gtataaatat aatgaagaat attgttttga taaatttaga agtatgagca
    36781 atgaaacaat acaatatatc tgtaatttat tgaatataaa aagagatgct tcacttagaa
    36841 ctgttatgga aagtgtaata ccaaagcttg gtgaggtgct tggattgcca aaggattttt
    36901 catataaaga tttgttttac tgtatatatg aaaagaaact tgaagaaaat aatataaaca
    36961 ggataaaatt atatgatttt aacaaggtta tagatgttgt aaatacaaat attgattcta
    37021 atagaaattt agcttctaat tttgaagtta gacctaaaat tagtattaaa aagaacaaaa
    37081 acacaaaatt attgacaaat tgtattataa aagacataaa aaatcaaagt taaataaaaa
    37141 acaaaaaaaa atttgtaatt atactcgaaa aaagtgtata ttagtagtat aatatttttg
    37201 tagcactagt gggaacaaaa aatgaccata ggacaaaaaa gtaccactta gtaccattaa
    37261 agtaaaaaac aggaaaacaa ttttaaaaaa tataaaatgt aaagtttata ggaggattta
    37321 aaaaaatgga aaaagtagtt agtatcaaaa atgcaagtgg attacatgct agaccagcag
    37381 gaatgtttgt taagaaggca gctgaattta aatcaacagt agaggttgta gcaaaagaca
    37441 aaactgtaaa tgcaaaatca ataatgggaa taatgagttt aggtttagct caaggagaag
    37501 aattaaagtt agttgtaaat ggagaagatg aagaagtagc tttagctgca atggttgaat
    37561 tagttgaaag tggatttgga gaatagatat aataattttt taaaaatttg atatttagaa
    37621 tctaatatta cttaaagtaa agtaacagag aagtattaaa catatacaga ccaacatttg
    37681 tagatattta atttctttgt tactttcatg tttatttaat cagaagatta agactattgt
    37741 taattgggta taaaaatata aatattttag aaaatgaaat aagatatttt taatcataaa
    37801 ttcagagtaa aaatacagta acaaatagtt tataaaattt tataaaaaat tataagtaaa
    37861 taaaactata aaaatgtaaa ttatttatat aaatttataa agtttatgtg ctagatgata
    37921 ttttttagga ggtagagtta tggcttacaa aggaataggt gcttctcctg gtgttgcttt
    37981 agggaaagcg ttagtagttg aacatagtga attagtaatt gaaaaaaaat ctatagataa
    38041 tgttgaagct gaaattgcta aattagaaga tgcagttgca gtttctaaag aagaattagt
    38101 aaaagttaag gaaaaggctt ctgaagaatt aggagcagag gaagcagaaa tatttgaagc
    38161 acatttatta gttttagaag acccagagtt aattggttct gcaatagata aaattaaaac
    38221 tgaaagtgta aatgcagagt atgctttaaa tgaaataaaa gagatgtttg ttagcatgtt
    38281 tgagtctatg gacaatgagt acatgaaaga aagagcggca gatataaaag atgttacaaa
    38341 tagaatactt agacatatat taggaattaa agttgttgat ttatctgctt taagcgaaga
    38401 agttgtatta atagcacatg atttaactcc atcagacaca gcaactatga ataaaaaaat
    38461 ggttttagga tttttaactg atataggtgg aagaacttct catactgcta tcatgtctag
    38521 aactttagaa atagctgcaa tcgttggatt aaatgatata acttcaaaag ttaaggatgg
    38581 agattttgtg gttttcaatg gagacacagg tgaagtaatc gtgaatcctg atgaagagac
    38641 tataaataaa tatactgaat taaaagctaa gtatgaagat gagagaaaag cattacagct
    38701 attaaaagga aaaccatctg taactttaga cggaaaacat gtggaattag ctggtaatat
    38761 aggaacacct aacgatatag aaggtctaat aaagaatgat gctgaaggtg ttggtcttta
    38821 tagaacagaa tttttataca tggatagaga ttctttccca acagaagaaa tacaatatga
    38881 agcatacaaa gctgtattag aaggaatgga tggaaagcct atagttataa gaacattgga
    38941 tataggtgga gataaagaat taagttattt aagtatggaa cctgaaatga atccattctt
    39001 aggttacaga gcaataagac tttgcctaga tagaaaagat atatttaaga ctcaattaag
    39061 agctttatat agagctagtg ttcatggaag attaagaatc atgttcccaa tgatttcatc
    39121 tttagaagag ttgttacaag ctaaagaagt tgtaaaagaa gttttagcag aacttgattc
    39181 tgaaggtgtg gcttatgcta aagatgtaga aattggtatg atgatagaag ttccatctgc
    39241 tgctgtaata tctgatgtat tggctaaaca cgtagatttc ttctctatag gaactaatga
    39301 tttaattcaa tacacttgtg cagttgatag aatgaatcaa aagataagct atctttacaa
    39361 tcaatttaat ccagctgttt taagacttat aaagactgtt atagacaatg cacataaaga
    39421 aggcaaatgg gcaggtatgt gtggagaatc tgctggagac caaaaaatga taccaatact
    39481 tttaggtatg ggattagacg agttctctat gtctccaata tcaatacttc ctgctagaaa
    39541 gttaataact tcagttaaag agtcagatat gaaaaaatta gctgatgatg tacttaatat
    39601 gggtactgct gaagaaataa aaagctatat agaaaagact tttaatatat aattaatgtt
    39661 atatagttac taaaattcat ttttctaaat aacaaaatta tattttacga ataaaaaaac
    39721 tatagtatat catatatact atagtttttt tgttatataa attacgtatc aaaatttgta
    39781 aaatgaatag atataattac taaatatgtg atagtattgg ctataatagg atataaaaaa
    39841 taatattgta aaaaaaagtt tatatttagt aatgaaaatt taacgtttta cttgaaatta
    39901 tgtgttttgt aatgtattat taaggctcta ataggaacat tttcatcaat ttttctatag
    39961 tgggggtagg aattatgagg tacaaaaaaa gaaatataga taagtcaagt gaactttcat
    40021 ttcaatctct agcaaaatat tttataactt tctatatagt aattatatta attattcttt
    40081 ctatgttttg tataaataca atatgggtta tgaaaaaaga taatcaagat ttattatcta
    40141 caacatcaaa tcgtattgaa gatagggtag gagaaacaat taagctattg aactctttga
    40201 gtaaagataa ttacataata gataatagtg tgaatggcat agataaaagt aaagaacttt
    40261 caatgtatag tgatgaattt gggtatatga tgatatgttt tgttgataag aatataattg
    40321 tgtgggatga agaaggtggt aatattagtc tagctggtcg tgattatatg cagaaacttt
    40381 ttgcaacaaa aaaatatcaa gttacagata gttttgcagc aggggctgat ggaaaaactt
    40441 taaactacac tattgcatca cctataataa agaatggaaa tgtagatggt tgtgtatttg
    40501 cagcaattta ctttgatgag ataaaggata tactcaaaca aggaaaaggt caacagcaac
    40561 agaatttcat attatttgga agtgaaaatc aaataatgaa tttaacaagt gatgaaactg
    40621 catatggaga gaagtatatg aagttatcgc agaaaacaaa atatcttgga accaatgcaa
    40681 aaaaagtaga aaaggatatg tttaataata aatcaggtga ttattgggct tttgaaaatg
    40741 gaaaattata ctttatgtcc tataaaccaa ttaagaacac aaattggagt ttattttgta
    40801 aagttaattt cttagatatt tttgcattaa atttaattcc tatgggagct attctatctg
    40861 ttataacttt agtatttatt attttgattt gtatggagaa aagcttcatg aaaaaacgaa
    40921 tggaagttat tgatatgctt ttaggttctg ttcaagaatt agaaaaacgt atatatcaaa
    40981 cagaaagacc tagtgaagta gactttaaag aaattattca gctcacaagt aaaggtctga
    41041 ctgatggatt aactggtgtt gtaacacgta ctgtattttt tgaccaaatt tataatcgtg
    41101 ttgaaatgga ggaaaatgat aaattatctg taatttcatt tgttgattta gatgatttga
    41161 aatgtattaa cgacttatat ggacatgaaa ttggggatat ggttttgaaa aatgttggat
    41221 atgtacttcg tgaatatgag ataaaatata atggtttaat tgggcgctat ggtggagatg
    41281 aatttgttat gttgttatct ggttttacat cgagagaaga ggtggaggat ttattggatg
    41341 agattgctat tcgcttacat actgaagtac taacagatga tggtatcatt caaactcatt
    41401 gtagtgttgg agctgtagta tgtagtgtaa aagacaataa agatatagat aatttattaa
    41461 aacaggctga tgaagcttta tactatgtta aacgtaatgg aaaaggtaat tatcatttag
    41521 tttaatgtat gtggaaggag tttatatcat atgaaaaatg tatctaaaaa attttttgta
    41581 tgtactatta ttgtattaat aacattttta tgttttagta aatttgctat ttatgttttt
    41641 gacaaacaag aaaagaaaga aacaaaagta gtagaaaaca tgttaaatgt ctacaagaat
    41701 aacattattt taaatctgac tgaaaaattt aattatagca aagacttgac atcagtttta
    41761 gtttcaaaca attattctat agataaatta aaacctattg cagatgaaat tcttaaaaac
    41821 aattcttgca tatatatttc agttgtagaa aaatataatg tagctgcatt tttttctaat
    41881 tctgtcaaaa aagatattat caatactcca atacaggaac tgaattattc ttattcatta
    41941 gcaaattcta tcaaaggatt agtcgtagaa ggtccttcta aagaccagtt ttcaaatgga
    42001 gatgtgtttt taattactaa tcctatttat aaaaatggag agtactgggg agaaattaca
    42061 gtagctttag atgccaaaaa agttgtagat tcttttaact taaataaatt aaaagaatct
    42121 ggatttgagt atgaactttg gcgtgtacac ctagataatg gttcaaaatc tacaatagaa
    42181 atttctacta aagattttaa tttttccaaa tcacatgaaa ttaagtttaa acttccgact
    42241 gtttggactc ttagcattgt gtacaaaaat ggatggaata ataagaatat agattttatt
    42301 gtatttgtta tattgttaat tatttctata ttaataggtg tgatgacatt tatttacatt
    42361 gaaaagaagt cgattagtaa ggaattaaat caacagagtc ttaaaaattt agaaactggt
    42421 attttgaata gagaaggttt tttaattaag ttgcaagagc atctgaatag aaaaaataat
    42481 gaaatagtgt tgctgtatat atgtattact aattatagta aatttgctcc agttatgagc
    42541 tttgaaaaaa gacaagatta tcttacacat atagtaaaaa atctagataa ttacataaaa
    42601 agttctcatt ttattgctcg tataagtgag gaaggttttg ttctagcttt agaagaaaat
    42661 tgtgataaaa atgaattgct taacattgaa aaagggattt ccttagagct tttacgaaaa
    42721 attaaagtag aaaataaaca agtattttta acgattggtt atggctcatc taggtgtgtt
    42781 gatgatagaa aagatgcaga atctctgtta ctttcagcta ttgaagatta tgagagaaga
    42841 tttccagcaa tgtctcctat tcatgatttt actaaaaagt gtgaagatat gcttgatgaa
    42901 aagaaacaga ttgtatttgg tgaatatcca gatttagaaa taaacaagtt gtctaaagta
    42961 atatacaaat attataaaaa agtacagcgt attatgtata aagattataa tattgatatt
    43021 ggaaataggc gagggtatat gcgtgatgtc gaagtattaa ttgattataa ttctgagaga
    43081 atgttatact tatttttaat agacatatgc aagtttggaa aatttaatga actgttttct
    43141 attgaaatag gagatgttat tttaaaagaa gttagtaaca aattaaaaac aattttttct
    43201 aattatctat atcgtattaa tggagatgta tttttaggca tttcaataga taaagaatct
    43261 tacttagata ctttacataa ggttaatgaa gtatttaata gttctttaag tgtagaagat
    43321 gtactttttg atgtaaaatg taatattggt atttgtcaat atccatatca tggtgaaaat
    43381 ccatatgacc ttctggaaaa ggtacaaatt gcattggagt atgcaaaaaa ggatgtcaaa
    43441 agtaatgtta aagtttatga taaggaattg acagaagaga tttaccatga aaataatatt
    43501 attaaggatt taaaaaaagg tctggaagaa caaacactag aagtttggta tcagccaatt
    43561 tttaatgtta gtaaaaactg ttatataaaa gctgaggcac taattagatt gagaaataaa
    43621 gagggcggtt attattctgc ctatgaagtt attacttatg cagaaaagca tggacttatt
    43681 aaggatgtag gtctatatgt actaaaaaag gcttgtgatg taactacaaa aataaaagat
    43741 aaaaatatag actttgaaca aatgcaatta aatttatctg ctcagcagat tgtacataag
    43801 cagtgtgcaa atgacatatt atcatgtatt gagaattgtg gtctagataa aaagtatatt
    43861 tctgttgaag ttacagaaaa agtacttatg gaaacttttg aaattgtaaa tgttactctt
    43921 gataaactaa aaaaagaagg cattagcata gctttagatg agtttggttc tggatttagt
    43981 agtataaatt atctggcaaa tttacctatt gaaaatttaa aaatagataa ggaattagta
    44041 gaacaaatta cctattctaa aaaacaattt gaattattaa aaactatagt tcaaattact
    44101 aagattaatg gcatggatat tgtagcagaa ggtgttgaaa caaaagaaac tctggattta
    44161 gttgtaactt caggtgtgaa tttgattcaa ggtcattatt tttcagaacc tttaagtgaa
    44221 gataaattta ttgaacttat gattgaagaa taaaggttaa taaaataaag atttaaggta
    44281 ttgaaaaata attaaaagta tttaataata gaattaggga agaataagtt tataagtaaa
    44341 aacaattgat tagtagttaa taaaataaat gtgatatcca aataaatcct aaatctaatt
    44401 tgagttttaa tatagatagt ctaaagtttg attattaaag atttaattgt aagttgttac
    44461 agttgatgat attgattaga gattaaagtt tagagtagaa agttacctta aatttaaaaa
    44521 tgcaagataa cccaatctaa aaattataat cactcgatag gtttaaggat ttatttgttt
    44581 attataaata ggagggtgtc tcaaaatgaa ctttttagtt tatgaggcac tctcttttat
    44641 atagaattaa atatatttta ttatttcaac aatgaaaaag aagcttatct ctattttgag
    44701 acagcctctt tgtatactat tattaattta atcaataaca taatttaaaa ttataatact
    44761 agttaagatt tcctgcttta ttagtaaata attctttaat agcattgttt ctggaaacta
    44821 aatcgttatc agagttgttt gtttttttca taatcactga ataacgtttt ttatttataa
    44881 aaaatattaa aatcttatca tcatcaaaat tgtattcttt atatctgtcg atagactcat
    44941 aacctagatt tagaatgttt ttgtctttta tactatctac atctaaaata tatgatgggt
    45001 cagcctttag taatatatta attaaacatt tttcttcacc agcacagaat aactccatct
    45061 tacttgatat agatttagat tgctctgaag ttatttttgc aggaataagg ttgtcattat
    45121 catctcttag aagataacca tgtgtgtctt gttgatatac taaattaacc tttttcttag
    45181 gaacactaat cattttatct aaatgtacat aatgatgatt ttcaacaaaa ccttcattta
    45241 atatttcaac aaagttatta attttaccta ggcaaaaaga ttctatagat tctttacaga
    45301 atttatttgt aaatggtatt atgtttacgt tttcctcgtc tgtattccat gctatagcat
    45361 aatccaacga atatacttct tcctctatat ctgcaaaatt atattgtact atgtttcctt
    45421 tcaaaattac tcgacctcca tcttataata tatttaatat actttataaa acttatatta
    45481 tatttaaata atatcataaa ttgaataaat atgatatagt aaataagaaa aaatttgaaa
    45541 aaaatcacta taaatgagta ataaatataa atagtgtata ctaatgggat ggaaaatgtc
    45601 cactattaac tttattaccc cacatatata agataaaatt attaatataa aatataatct
    45661 atcgacaatg aatagacttt taaataaact taatataaaa ttaattaaat aagtgcttaa
    45721 aaacgattta ctttaatgat agaatcatat taaaggagga taattttatg gatataaaga
    45781 ataaaattaa atctatattt ttaccagaaa aaaatgacta tttagatgat gaagaatttg
    45841 agtatgatat agaaaataat gaagaagatt taaaggaaga taacaaagta catttaaatg
    45901 atttaagcag agtaaaatat gattacagag agttaaaaga catagaaaac caaacagaag
    45961 agatgtgtct gctagcagta aagcaggatg gtactataat tgagtttgta aaggacaaga
    46021 cttataaagt atgtatggaa gcagtaaaac agacatataa atctcttaag tatataacaa
    46081 atcaaaatga ggatatttgt atagaagcag taaaacagaa ctacagagct ttgtactaca
    46141 taaataataa gacagaaaat gtactaattg aggctataaa aaatgcatca acttatgatg
    46201 tcatggaagt atttaaattt gtggaagagc aaacagaaga tgtatgtcta gcatttatag
    46261 aaagggcatc taaaaatgat gttgcagaga tattaaaagg aataaaagag caaactccag
    46321 ccatatgttt agaagctgta aaaaaagatg gaaaatcttt agcttatgta aaggaacaaa
    46381 gtaatagtat atgtttagaa gctgtaaaag aaaactacag tgcactatct tgtgtaaaag
    46441 agcaaactga agaaatatgt atagaagcag taaaacagaa tgactttgca ttgtattatg
    46501 taaatgaaca gacagaaaaa atatgtatgg aagcagtaaa aagaagttat atggctctac
    46561 agtatgtaaa taagcaaaca gaagagattt gtttggaagc agtaagaatt gatggaagag
    46621 cattacagta cgtaaaagag caaacagaag aaatttgctt ggagtcagtt agacaaaatg
    46681 gaaaagtact gcaatatgta aaaaaacaga ctgaaaatat atgtatagaa gcagtaagag
    46741 gttcatttga agaacttgaa ataaaagaaa tattaagtta tgtaaagata ccaacagaaa
    46801 gaatatttgt agaagcagta aagcaaaatg gaaaaattct taaatatgta gaaaatcaga
    46861 cagaattaat atgtttagag gcagtaagag aaaactataa tgctttagct tatgtaaagg
    46921 aacaaacaga aaagatttgt ttagaagcag ttaatcaaag ttatgaagcg cttaaatatg
    46981 tgaaagaaca aacagaagaa gtttgtctaa aagcagtaaa acaagattat agaatgttga
    47041 aatatgtaaa taatcaaaca gaaaaaatat gtttagaagc agtaaagcaa aattatagag
    47101 ctttagaatt tgttgataat caaacagaaa aagtttgtct tgaagcagta aaacagaata
    47161 gaaaagcact acagtatgta aaacaaaaac aaagttaaaa ggctaaaata tatagaaaac
    47221 atatgcaaat aaataaaatt tgatattttg taataaataa aatgggtatc tcaaaaggaa
    47281 ctttttagtt tgtgaggtac tctttttata tgaaatgaaa tatattttta gccttttaac
    47341 aatggggaaa aggtttattt ctattttgac ataggctttt tatgcatata aagcttgata
    47401 aaattgtttt attataattg ttttgttata taaataataa gaagaaaatt atataggtct
    47461 ttttttgacc agttttacat ttttaacaac tagttttgta aagtatattg aattttctca
    47521 aaaaagaatg tactctatat atgtaaaatt tttttggagg taaaaatgtt taaaagatat
    47581 gctgaaaaaa tgacatctgt tttaatttgt aataatatga tagataataa tgaatctaaa
    47641 gtctattctt atggatttga aatattaata gctttcatag ttaatataac caccatgctg
    47701 tttataggtt ttttatttgg taaatttaca tatgtattat tttttttaat gtgttattgt
    47761 ccaataagac aattttcagg agggtatcat gcagacaatt attttagatg cttattaacc
    47821 tttattttta taattttatc tacaatctta attatagaaa atataaatat agacttattt
    47881 aaaaatatta ttatgattat tgcaagtgtt agttgggttg gaatttgtgt tctgtgccca
    47941 atagaacata ggagtaaccc tataagtgat agggaaaaat tggtttataa gaaaactgct
    48001 atatttatat ctacagtagt gttattgata acaattttaa gtctttcttt gagtatattt
    48061 gtagattatt tcacatatag cgcatttgcc atgttttgga tttttgtgat gttagtatta
    48121 ggtaagttaa aagctaaagt ataagtaaaa tatgtatgag ggagagttaa gttatgaaaa
    48181 agtttattgt aagatttatg aagtttgcta gctcattggc acttagcact gctattttgt
    48241 cagctaatag tacctgtcct tggattattc atcagcctaa agtacccaaa gaaatcagca
    48301 atctaaagaa gacaaattaa atacaagcac ttatttatac aaaattatca ggaaaaaaga
    48361 aattattata ttttaataag attaaaacaa tataaaatca gatacaaaat ttattttatt
    48421 tattttatag gagcctaata cctatttggt aatatattag tgcgccaatt tagggggata
    48481 tagtgtattt aatgaaatga cttacggaga gtaagtcatt tttgtattgt atgtatttta
    48541 tgtaaactta tgatataatg aagggtaaag tttaattaaa ataataaaaa actttagtat
    48601 agatagtaat ttaggaggta gggtatgagt atgatacata aattttctat gaatggatat
    48661 aatatcgttt tagatgtgaa tggtggagct gttcatgtgt tagatgatgt tgcatacgat
    48721 ttgttagatt tttataaaga aaaaagtaaa gaagaaatat tagagatatt aaaatcaaaa
    48781 tatcaagaag aaaaaataaa tgaagcatat gaagaaatat taaatttgga aaaagagggt
    48841 cttttatata cagaagatac atatcaatat catccaagct ttgtacatag agagcctgta
    48901 gtaaaagctt tatgtttaaa tgtagctcat gattgtaact taaaatgtaa atactgtttt
    48961 gcagctcaag gtgattttgg aggagaaaaa gaacttatga gttttgaagt tggtaaggca
    49021 gcaattgact atttgattgc taattcagga agtagaaaga acctagagat agatttcttt
    49081 ggtggagagc ctttgatgaa ctttgaggtt gtaaaacaac tggttgacta tggaagaagt
    49141 gtagaaaaag attataataa aaatataaga tttacaataa ctacaaatgg tgtactgcta
    49201 aatgatgaga ttatagatta tataaatgaa aatatgcata atgtagtttt aagtttagat
    49261 ggaagaaaag aagttaatga taatatgaga ccaactttaa atgataaagg aagttatgat
    49321 attacattac cacgatttaa gaaacttgtg gaaaaaagag caaaagataa gtattattat
    49381 ataagaggta cttttacaag agataattta gatttttcaa aagatgttat gcattttgca
    49441 gatttaggat ttaaattaac ctctgtagag ccagttgttg gagatgagag taatccatat
    49501 gcacttagag aagaagattt acctaagata tttgaagagt acgaaaaatt tgctgtagag
    49561 tatgcagata gacaattaca aggagatgga tttaaatttt tccattttat gatagaccta
    49621 aatcaaggtc catgtgtaat aaagagaata actggatgtg gagctggaaa tgagtatctt
    49681 tctgtaactc caaatggaga tatatatcca tgtcatcaat ttgttggaaa tgaagaattt
    49741 aaaatggcaa atatatttga tgaagaaata gtacttccag aaaatttaaa aaatatgttt
    49801 agagaagctc atgtatatac taaagaagag tgtaaacaat gttggaataa gttttactgt
    49861 tcaggtggat gtcatgcaaa tgcgataaac tttaataatg acatatcaaa accatatgaa
    49921 ttaggatgtg aaatgcaaag aaaacgtaca gagtgctcta taatgataca agctaagtta
    49981 atgttagaag gagcaaccaa ctaaatttat attttaaagg agttgtttat atatgattag
    50041 agattattta gaagataaac ctttaattga cgaaagtgta tttgtggcaa aatcagcaga
    50101 tgtaattgga aatgttaaaa taggcaaaga ttcaagtata tggtacaatg cagtagttag
    50161 gggtgatgaa ggaccaataa ctattggaga aaacactaat atacaagatt gttctatagt
    50221 gcatggagat acagaaacta taattggtaa caatgtaaca gttgggcata ggtctatagt
    50281 tcatggttgt aaaattagtg ataatgtgtt aattggtatg ggttcaataa tattggataa
    50341 tgctgaaata ggagaatata ctctgatagg agcaggtaca ctaattacat ctaataagaa
    50401 gtttccacca ggtgttttga taatgggttc tcctggtaag gttgttagag agcttacaga
    50461 agaagataaa aaatatattg atgaatctta tgaatggtat ttagaggcag cacaaaatca
    50521 aaaatattag tttaaagagt ggttgtttca aaacatattt aaatctgttt tgaggcaacc
    50581 actaatttat tttattagat tttgttgata ttttagtttt caaaaagtat ttgattaaac
    50641 cagatataaa atgtcaaaaa taaaaattaa ctgagttaaa taattttaat aaaattggta
    50701 gtatatgtga taaaattaaa tattaaagag gatataggat attagaatat caattggtga
    50761 aataatgtca tatacgataa attaaggtgt aagtttttgg gtatacctat cttaggagtg
    50821 aaaagatttg agaataagtt atagaaattt aaagcgatat agagaaattg gatatgtttt
    50881 aataaagtat ggttttagtt ttattgtaga aagactaaat atagaaggaa ttgcctataa
    50941 aataccacta tttgacccac cagaagaaat aaaaaatatg acaactggtg agagaatgaa
    51001 aagagtttta gaagaactag gacctacata tataaaaata ggacagatat tgagtacaag
    51061 aaaagacttg ttagaccagg atataattga tgaaatatca aaactcagag atgatgtaga
    51121 gaaatttgat tcaaatatag ctattgatat atttaaagaa gaagtgggtt taagtataga
    51181 agaaatattc ttagaattta aagaagaacc aatagcagca gcttcaattg gtcaagttta
    51241 tgaaggtgta cttaaaacgg gagaagaagt aatcgtaaaa attcaaagac caaatataga
    51301 gaaaataata aaatctgatt tagagattct tagaactatt gcaaatactt taaaagattt
    51361 aaaaaaggat tttaatttag atttagtaca gatgattgaa gaatttcaaa ctcaattaat
    51421 gagggaactt gattatacat ttgaagctat aaatgcaact aaattctcta ggatatttaa
    51481 aaatagtgat gaagtatata tacctaaagt atattcagaa tataatacta agaaaatttt
    51541 agtaatggag aaagttaatg gtacaaagtt aagtgatgta gaaaaaataa ggagactagg
    51601 ttataacaca aaaactattg ttgaaatagg agttaggtca ttttttacac aggtattatc
    51661 tcatggattt tttcatgcag acccacatcc aggtaatata ttcgtagttg ctaaaaataa
    51721 gatagcatat atagattttg gaatgattgg aattattgat aataaaactt taaaccaatt
    51781 aaatgaaatt gcattagcag gtgtagaaaa gaatgttgac aagataatat atctattgat
    51841 agaaatggat gcattaaatg gagaggctga tattaaggga cttagacagg atttacttta
    51901 tctaatacat tattactatg atatttctat agaaaaaata aatgtaacag atatattaaa
    51961 tgaactattt aggtttttta gacagtataa aatagtcatg cctgcacaat ttgtaactct
    52021 tgcaaagaca gttataacat tagaaggaac aagtagaact ttaaacacag atttttcttt
    52081 tggttctatg ggaaaagagt ttatgaaaca tcattataag agtaaattta accctaaaaa
    52141 tgttgtttta agttcaagac aaaatgtaga agaaatatta ctggacataa aaactattcc
    52201 aaagcaatta aaagcaattt taaaaaatat agaaagaaat aatataaaaa tgcaaattga
    52261 agatgttaaa atgacgaggt tagaaaattg tataatagag ctaacatctc aaatatcttt
    52321 gagtttagtg ttggcatcta ttatagtagg ttcttctctt ataattgcat ctccaaatat
    52381 agaaaataat atatggataa aatttactgc aatagcgggt ttctttatat cctttataat
    52441 aggcctttgc ttagttataa gaagtattag gtcaaaatac aaaaaagatt agggggaatt
    52501 aaatttgaaa aaatggatat tgaagtataa aggtaagata gaggaaagtg aatttagcaa
    52561 aaaacttaat atttccccgg aaatctgcca aattttaaaa aatagaggga tatgtactga
    52621 aaaagattca gaaatattta tgaatccatc tttagattat ttaagagacc cttttttaat
    52681 gaaagatatg caaaaagctg ttgatagaat aaagttagca gttgagaaga acgaaaaaat
    52741 ttggatttac ggagattatg atgttgatgg tgtatcatct acatctatct tgtgcttata
    52801 ttttaagagt ataggttaca atgttgatta ctatattcct aatagattag aagaagggta
    52861 tggtataaat gaagatgcta ttaagcttat aagctctagg ggatgtgact tgattataag
    52921 tgttgactgt ggaattacat cagtgtctga ggtcaataca gcgaatgatt tgggcataga
    52981 tgttataatt acagaccatc atgaatgtca aagtgaaatt ccatcagcct ttgcagtaat
    53041 aaatccaaaa caagaagatt gtaattatcc atttgattca ctatgtggat gtggtgtagc
    53101 atttaaaatg attcaagcct tgactccaaa agaagaattt aaaactagta tgtataatta
    53161 tttggaaata gtaacactag caactatttg tgatattgtt ccacttatag atgaaaatag
    53221 aataattgta aaaaatggtt taaaatcaat gaaagaaggc aaaaatattg gattaaggga
    53281 gcttataaaa gtttgtggtg tagaaagtga taagataggt tcttctcata taggttttgc
    53341 aataggtcct aggataaatg cttcaggtcg attgggatat tcttacttag gagtagagct
    53401 atttactact caatcacaag aagaggcagt agaaatagct agtatattgg aagaaaaaaa
    53461 taatgaaaga cagatgatag aagctaagat gtatcatgaa gctgaagaaa tgctaaagtc
    53521 taatagcaga tacaatgatg acaaggtgtt ggttttagct aaagagggtt ggcaacatgg
    53581 aataatagga attgtagcat caaagttaac tgaaaaatac tacaaaccaa caattcttct
    53641 aggtatagaa aatggggagg ctactggttc agcgaggtca ataaaaggat ttaatatatt
    53701 tgaagctctc ataaagtgca aagacttgat gactaagttt ggtggtcatg aacaagcagc
    53761 agggttatcc ttggattcag acaatgtaga aattttagca aatgaaataa ataaatttgc
    53821 agattataat ttaactgaag atgatatgat agagaatgta aatgttgagt ttgaattaca
    53881 agaaaatgta ataaatttaa atcttgtaga agaattacat aagttagaac cctttggatt
    53941 aaataatcct aatcctagat ttatagttag aaattatatt ttaaaagatt tgaaagttat
    54001 aggtaagaat caacaacatc tgaaattaag catagaaaaa gagaaaagct atgaatgtat
    54061 aggatttaat atgagtcatt taaaatcaat gtataaagta ggagacaagg tagatgtact
    54121 attccaatta gatgaaaata actatatggg aaataggaaa gtacaatttt tacttaaaga
    54181 tatacgattg gctcgaccta aaagtgcaag taatgacaaa ctttcattga aattaatgtc
    54241 aaaaataata ccaaaagata ctcaaagcct gtataatata tctgtgtctg attttgaatt
    54301 atttgatgga aatacagata taaatatatt tgattatttt gaaaaagata cactaataat
    54361 atctaattct ataaatggat tttatagagc aatgtcagat atatcactta tagatttgga
    54421 ttttaacata aattacaata ttattgaaga tgatagcaaa aatactgata aattagagct
    54481 tatattttct cctaatattg ataaaataga cttaaaaaga ta
//
LOCUS       DAJMZY010000014        54319 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.014, whole genome shotgun sequence.
ACCESSION   DAJMZY010000014 DAJMZY010000000
VERSION     DAJMZY010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 54319)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 54319)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54319
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.014"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            complement(310..1179)
                     /gene="gatY"
                     /locus_tag="OE968_000811"
     CDS             complement(310..1179)
                     /gene="gatY"
                     /locus_tag="OE968_000811"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase subunit GatY"
                     /protein_id="HCP7218124.1"
                     /translation="MALVTTKQILLDAQEGHYAVGAFNVENMEMVMAVIEAAEELKSP
                     VILQTTPSTIKYAGLDYYLANVKVASEKASVPVAMHLDHGSSFGLAMQALRVGYTSIM
                     IDGSHESYEDNISISKSVVDACMPSDIPVEAELGKVGGKEDDLDGGDGGAYTDPLEAK
                     EFVERTGVSSLAVAIGTAHGLYKGEPKLDLDRLSEIREVVSVPLVLHGGSGIPDEVIK
                     ESIKRGICKVNYATELRIAYSNGVKDVLNSDPEVIDPKKYGKKGLESVKDFVKSRMEV
                     CGCVGKAIEIVKC"
     gene            complement(1199..3115)
                     /locus_tag="OE968_000812"
     CDS             complement(1199..3115)
                     /locus_tag="OE968_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIABC"
                     /protein_id="HCP7218125.1"
                     /translation="MGKKMILGVTGCPTGIAHTFMAEEALKNSARELGCDIKVETNGA
                     IGVENKLTAKDIEMADAIIVACDKNVDMDRFNGKPVIEVPVKEGIHKANELIQRCIDG
                     KVAIRKGNLSSSKIAEEGNLSFGQKLYKDLMNGVSHMLPLVVAGGVLTAISFLWGIYS
                     FDPNSEQYNQIAATLKSVGGYSMNLMVPVLAAFIAQSISGRAGMLAGLVGGMISFDTG
                     SGFLGGIISGFLAGYLVKLFVHLLRKLPRQLEGLKSIFIIPIVSVGLVGVAMLLLGGP
                     CSALNNAMMNFLSGLQNSSPIILGIVIGCMSAFDMGGPVNKAAYVTGTMLLGQGNYLF
                     MAGVSAACITPPLVIAIASTLFKNRFTEEDRAAGLINYILGSTHITEGAIPFAAKNPL
                     KVLPVLMIASSISSILTYIMKIEVPAPHGGFLVLGLVNKPLLWVGCIFVGSLVGAVLY
                     MMVTPKVVNEKNTIENTNVTKDEHKNESAESENVSNNISLYSEETVILDVKGKNKTDV
                     IDEMIGILDKSSVLLDKKKFKEEILKREEISSTGFGMGIAIPHAKTDAVKVPRVAVGL
                     SKEGFDFESEDGSLAHIIFMIAATDNGDNLHLKTLSQLSSKLMNEEFLNELLNSKTSR
                     EIVSKLNNEEIKSV"
     gene            complement(3118..4038)
                     /locus_tag="OE968_000813"
     CDS             complement(3118..4038)
                     /locus_tag="OE968_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase family hexose kinase"
                     /protein_id="HCP7218126.1"
                     /translation="MIYTLTTNPAIDMNISTNGIKRKLVNRTSNAVYSPNGKGLNVTF
                     VLGHYGIESKILGFFGGFSGKYIVEESEKRGFDVLPTWVEDTTRINIFLNDGSDEFKF
                     VNSGSYVNEKQKLDMLDKIQSLEDISYLSISGSLPPGIDDNYYEDIFKICENKSIKTI
                     LDISSPKLKELLQYNPYLIKPNDEEIKDIFGIIVRDEEDIKDVLKLLHLKGAQNILLT
                     LGEKGSYFYNGKSIYYASAQPVTVVSSACAGDSALAAFLSIWLENPEHIEEALKRSAA
                     TGASVAESNGIGNLENVEDYIKNIRVRKVV"
     gene            complement(4140..4892)
                     /locus_tag="OE968_000814"
     CDS             complement(4140..4892)
                     /locus_tag="OE968_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HCP7218127.1"
                     /translation="MIIELNKSNSENLTKTELEIIKFINENESILPELSIVEIAHETY
                     SSPATVSRAIRKCGLNGFNELRYRLTVKDENDDIQNMGDIINKSFIEAQRVIEQISLT
                     TLINIIKTVNKSSKIYILARGLTEYVAKEFSLKLQLLDFNVVFINDPNIMKIKSKSIK
                     KDELIIIFSLNGNTIELVESAQNANLVGAKVITCCCSESAKLIKYSDLYIVGYKHEHI
                     SISEYEVSSRLPLYIISRIIIDYMVRYNNSEN"
     gene            complement(5284..6729)
                     /locus_tag="OE968_000815"
     CDS             complement(5284..6729)
                     /locus_tag="OE968_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HCP7218128.1"
                     /translation="MIKLGKFPKGFLWGGAVAANQLEGAWNEGGKGWCLADVHMYDKD
                     RDISKPYESDMTIERIKFAMKDNNGYYPKRSGIDFYHTYKEDLKLLKELGLKCFRFSI
                     NWARIFPNGDDLEPNEEGLKFYDNLINEVIDNGMEPIVTLLHYETPLNLVLKYKGWSN
                     RKVVDFFVRYAELILNRYKNKVKYWIVINQINLIHYESFNSVAFCVDQVDNVEETRYQ
                     AIHHQFIATALTKKLGKEINSDMMIGMMMADCTSYPEDCDPENVVFALKRNRLQYFFT
                     DVSFRGEYPVYIKRFFKENNINIVMEEGDDKILKENTMDFLALSYYYSTTVSASKNTM
                     NPTDNIKNPYLKANPWGWAIDPKGLYNTLSQYYDRYQKPIMIAENGFGMHDKFEDGKV
                     HDSYRIDYLGKHIEQIGEAIADGTEILAYCMWSPIDIVSCSSQEMEKRYGFIYVDIDN
                     NGNGSKKRYKKDSFYWYQNVIRTNGEELKEK"
     gene            complement(6751..7104)
                     /locus_tag="OE968_000816"
     CDS             complement(6751..7104)
                     /locus_tag="OE968_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HCP7218129.1"
                     /translation="MTIEEHIIDEELVEVAMQIILRAGEARTEIKHALNDLEKFDYRN
                     ADLKLAKAKGFMTEAHRAQTKIIQGEAGGEKRAHSLLFAHAQDTLMTIFSELNITMSL
                     VGIVKSIEYKVNNSK"
     gene            complement(7133..8380)
                     /locus_tag="OE968_000817"
     CDS             complement(7133..8380)
                     /locus_tag="OE968_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCP7218130.1"
                     /translation="MGRVFMNKFIDFLSEKFTPVVNNMTKNIWVQSVQSTIMKVLPMV
                     FVGSLVTIVSVLKNYISFLPDLSPINQYTFGLLGLFIAFLLPMEIMKNKKFESMSVVA
                     GLAGAGLMLMMIRPEITNEGAIFNFNRFGGEGMLVSLVAGLFSGLIMSLFGSFSFFGE
                     DSALPDFVSKWFDNMLPITVIMFVGWGLIYGLNFDMFEIIVRVFKPVSDIAQTLPGFV
                     LLNFLVVFIYSLGISGWVLSPITYSIQLGAIAANAAAVASGGVATNIYVYEVIQTGWI
                     TLGGLGATLPLVIMMCLSRVGRIKAIGRACIVPSIMNINEPVIFGAPVAWNPFLMLPM
                     WIGTVVISITTYLSMSMGFVTIPSKVFNLWYVPFGISTFTVNQDVRGLIVLAINIVLL
                     FMIWYPFFKAYEKEEIKLESQEV"
     gene            complement(8388..8705)
                     /locus_tag="OE968_000818"
     CDS             complement(8388..8705)
                     /locus_tag="OE968_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCP7218131.1"
                     /translation="MKNIRVLLACGSGASTGFMATSMRKSAKKKGIEADIKARSESEI
                     DKYLSEIDCLLLGPHLDYMKEEIQQKANEYNVPVACISKTAYGRLDGAKALEEALELI
                     SNK"
     gene            8947..10860
                     /locus_tag="OE968_000819"
     CDS             8947..10860
                     /locus_tag="OE968_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HCP7218132.1"
                     /translation="MKTSKKELFLNFIKTQHDWIDSSTLANYLNVSTRSIRKYVNEIN
                     SNGEFILSSKKGYKVNLNNNCQTKVDSSENISPDNRLNLILKELIVNSNGINIFDLSE
                     DLFVSPATIEGDIVKANKFIGSYNLKIKQSKFLLKLIGNESAKRKLMSSIIFKETGSD
                     FLSLFDVQKIYQEYNLTKLKENIIYILKKYNLFINEYAINNILLHLMITIDRIKKNNY
                     IESVEVVNYIDNNNDISISRDISNFLESEYNITLTSAELYYLVFQLTNKTTVLNYHEM
                     DTKSLPNYIDEHFVKLTKKIIKNVYDLYFIDLSDDEFVVKFTLHVKNLISRAKNNQVL
                     RNQIPQKLKDSYPLIYDISVYICNQIQILENIEIDEDEISYISLHVGSFFDRQKLLED
                     KILCALITPNYYDLQFKIVRDLEKRFNESIEIIQIFSDTHNLDFDNKVDMVITTLPIS
                     DRCPIPFVYVNPYLNRKDYDNIQSKFIQIKDRKNILTVQNHLEMYFSESLFMKNIYLD
                     SAKDYIRFMGNILYENKYVKPNYIDDVLIREKMSSTAFNNNVAIPHSMKMDALKTGVC
                     LIVNDKPVKWGEEKVQIIAMIPINEKEKEKFNYIFESFIEILSEWNNVKELTKADNYS
                     SFMNRIAYLIQNI"
     gene            complement(10983..12137)
                     /locus_tag="OE968_000820"
     CDS             complement(10983..12137)
                     /locus_tag="OE968_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HCP7218133.1"
                     /translation="MKILISIDSLKGSLSSIEAGNAIKKGILKVKEDAQVKILPLADG
                     GEGTVDALVQGMNGKKDTIEVTGPIAKKVDATYGLLKNTSTAIIEIAQASGLTLVPTE
                     LRNPLYTTTYGVGEIIKEAINKGYRNFIVGIGGSATNDAGIGMLQALGFEFYDENNKL
                     VGLGGKVLNEIRHIKIENRLKELDECKFKIACDVNNPLFGKNGAAYIYGSQKGATSEI
                     IEELDNGLRNFSKVVKNYLSKDVANVEGAGAAGGLGFAFLAFLNSKLESGIKIILEEI
                     KLEEELKDADFVITGEGRLDNQTAMGKAPIGVAKLAKKYGVKVIGLAGATTEDAVKCN
                     EEGIDAYFSIVNRAMTIEEAMDKATASENMTATTTQIFNLITSIQQSKNM"
     gene            complement(12397..15012)
                     /gene="mngB"
                     /locus_tag="OE968_000821"
     CDS             complement(12397..15012)
                     /gene="mngB"
                     /locus_tag="OE968_000821"
                     /EC_number="3.2.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosylglycerate hydrolase"
                     /protein_id="HCP7218134.1"
                     /translation="MKKNVHIVPHMHWDREWYFSTEESRILLVNNMEEIMDMLENNHN
                     YPYYVMDGQTAILEDYLAVKPECKERIKKLVQEGRLIIGPWYTQTDEMVVGGESILRN
                     LLYGIKDCDEFGEYMKIGYLPDSFGQSAQMPQILNGFDIKYSMFWRGCSERKGTNKTE
                     FNWKSDDGSSVLVQILPLGYAIGKYLPMNEDELRTRMDKYLPVLDKGATTDHIILPNG
                     HDQMPIQKNIFEVIYKLKECYPERKFFLSRYENIFKELEKNEDIDTIKGEFLDGKYMR
                     VHRSIFSTRMDIKSANARIESKITNILEPLASIAYSLGFEYHHGLIELIWKEIMKNHA
                     HDSIGCCCSDKVHHEIMNRFFLAEEKVDQLITFYKRRIVDAMSCEMALDKLVAFNLMP
                     YDRNEIVSAQVITKMKAFEIFDKDNNKLDFEVVHKEVIDAGLIDRQIVHYGNYDSFMV
                     YTINFKDKIPAMGYKAYMIKEVEHMLEKAYEVCDMVDNDFYTIQVNENGTLKIFDKKL
                     NKTFENVLLMENGGDEGDEYDFSPLPNEKLIFNDNIVANSTIKKNRFNNEIKINYRLK
                     VPKDIQARKNNRADSFIDFDIVINVPNDKAIIDVVFNINNQARDCRVRTYIPTNIASK
                     FSVSDNQFGHIKRSVYDDAMEVWQQEEWSERPDSIYPMLTFVGLSDKEHGVAVLTNST
                     REFEIVGEKFDTIAITLFRSVGFLGKEEMARRPGRPSGIKLPTPDSQMIGDIKIDLAI
                     VTHEKSTLEANVANMAKEYLTKIQTYNKMPYNAMKLNQSEIEVDYSYSLLKETNKDLV
                     LSVVKKAEKQEALVVRFYNSKEETKSANIVFNKNIKTAKWINLNEKELESISIDNNSV
                     NVECLMNQVKTILVK"
     gene            complement(15156..17081)
                     /gene="mngA"
                     /locus_tag="OE968_000822"
     CDS             complement(15156..17081)
                     /gene="mngA"
                     /locus_tag="OE968_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS 2-O-a-mannosyl-D-glycerate transporter
                     subunit IIABC"
                     /protein_id="HCP7218135.1"
                     /translation="MEFKKITNENLVFLKQKIKTKKDAIKFLARKLYDEGKLTSYEEY
                     LEAVMYRETLSPTGFERGLAIPHGKSKSVKEAAFAAMTLETPIENWESVDPNNKVEII
                     FLIAVPENEGGNTHIQILSELVTRLSNEDYMNMLLNSKTKKELFNNLDIKEKKEQIKE
                     EIRIQNESKKIILAITACPAGIAHTYMSAEALIKAGKEIGVDVYVEKQGANGMVDPHT
                     PDIIKRADAIIYATDVAPKNTERFEHLPNIKTSVAAPLKRAKEIIYEALEVAQKQGKG
                     DYIEKSSDISYCEKSSWKKDVKSAILTGVSHIIPLIVAGGMILAFAVLASQAFGLQEL
                     YNQEGSWLWQLRKLSGGMLGTLMVPVLSAYMSYSLAEKPGLGPGFAAGLAADLIGSGF
                     LGGMLGGLLAGYIVKFLKKNIPAKGTLAGFVSFWVYPVVGSLVVGLLMLFVVGKPVAA
                     LNNGLINWLNGMTGVNAILLGAIIGAMVSFDLGGPINKAAYTFAIGAIASGNFIPYAI
                     FASVKMVSAFGVTIATVLGRDLFSESEKEIGKQTWILGLAGITEGAIPFMIEDPIRVI
                     PSLVAGSAITGSIVAFFNIGLQVPGAGIFSLALLEGSMSGFIIASIWFFAAVLGAIIS
                     AVLLIITRKQKNQRKIH"
     gene            complement(17211..17936)
                     /locus_tag="OE968_000823"
     CDS             complement(17211..17936)
                     /locus_tag="OE968_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HCP7218136.1"
                     /translation="MEFYERAKKYEYKFTDTEDMIIEYMRKNKEEIVKLSIQSLADKF
                     FTVPNTIVRLCKKMEYDGFSQLKNNLKEELKNEDKEPKNGFESDIKKTLELIDYEKIN
                     KVADIIQKSRSIIVYGIGQNIPLCEILVKEIRGGHDNITYYSQRHEVLHDIGKLGEQD
                     MFFALSLSGETKEVIEVAKTAVNKGCKVVALTHICENQLQQIADISLYCYSTIKQVNG
                     YNISDKVPIMMIMRAIIEQYWLR"
     gene            complement(18199..18969)
                     /locus_tag="OE968_000824"
     CDS             complement(18199..18969)
                     /locus_tag="OE968_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ChbG/HpnK family deacetylase"
                     /protein_id="HCP7218137.1"
                     /translation="MKKLVVRADDIGYSEGVTLGIISSYKNGIVTSAGIMVNMPFSRQ
                     AIEMVKNDDVCFGLHVNLVIGEPCCKEHIKIKNLLDEGGKFVSSKIRRTQLLTGKEVF
                     NYEEVYEEVCAQIETYKLYMSKLPEYIDIHGIEEDVSISAMCDAAKEYGIPSCPYYLD
                     SCISMPSKYPQNDFYKLNKSFVKLFEEKYINLDKDITLMVTHPGFIDYSLIKSSSLIQ
                     ERVYEHAMLCDKEVKMWLKRNNIELVDFKDIFKSNNYI"
     gene            complement(18971..20398)
                     /locus_tag="OE968_000825"
     CDS             complement(18971..20398)
                     /locus_tag="OE968_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HCP7218138.1"
                     /translation="MMQQLSLLGKTMLVPIAVMPAAGILGLLFGPNMLNVPAISNISN
                     IVFSNVDYLFLLGAASAYSKSKDKTSVMVAAVVAYMIFKSNLELLNDTLNAGVFGGII
                     VGACIAWTYNKTYKVKVPAFLSFFAGEKCVITLSPVVALILSYIFSLLWIYPQAAMNQ
                     FGFWLGGAGAIGIFLFLFCNRALIPTGLHQVLNAYILFEMGEYTTSTGEVIRGEIPRF
                     MAGDPNAGFFWTGFYIIMMFSIPAISYAIYKTAQDKKKQEVKGAMTAGALTSFMATVT
                     EPIEFSFLFASPKLYIIHSFYSGLGGVVLYLLGVRLGSFNGASIIDYVLSFSYGDKAW
                     LVIPVGVVFFVLYYVTFKYIIIKDNVQTPGREVEIEIGDKVSEKEKNLKLSHGNFSYM
                     AKQIIKNCGGYENIVTLNNCMTRLRLEVKDATILNDDNIKKTGAKGVIKLSNTSVQII
                     IGTDVVKVKDEMEMQLDELRKQADA"
     gene            20789..21511
                     /locus_tag="OE968_000826"
     CDS             20789..21511
                     /locus_tag="OE968_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCP7218139.1"
                     /translation="MAKNKFSEIYEVLKEEILDGKYTSNMMLPTELQLIERFSCSRNT
                     VRRAISQLNTEGYVQSIKGKGVVVLENSCSNDFFLNMHNFKGVESIVEDKKVNTATSV
                     LHFSKILIDNKLSKKTGFKVGSEVYYLHRLRYIDNIPKILDINYFLCSIVKDLDVSIA
                     QGSIYKYIEECLGTKIVSSRKIFKIEKATELELKTLPLNDYNCVGVIKNSVYTDDGKL
                     FEYTESKHTPETFVFMDVTQRY"
     gene            21708..23375
                     /locus_tag="OE968_000827"
     CDS             21708..23375
                     /locus_tag="OE968_000827"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HCP7218140.1"
                     /translation="MKNWWKKATVYQIYPKSFKDSNNDGIGDINGIIEKLDYLYYLGV
                     DLLWLTPMYVSPQRDNGYDIEDYYNIDPKYGTMSDFEKLLKEAHKRDIKIMMDMVLNH
                     TSTEHKWFKESKKSKDNPYRDYYFWKDAKPDGSVPNNWISRFSGTAWKYDETTNQYYL
                     HLFEETQADLNWENEKVREECYKILEFWADKGIDGFRLDVVNLLSKTPGLPDDPITGP
                     KGDGRTHYADGPRIHEYLHNMNQKVFKPKNIVTVGEMSSTTPEECINYTRENREELSM
                     VFSFHHMKTDYKGGAKWTNEMFSLDKLKKAQSDFQYKMYEGKGWNALFYSNHDQPRAL
                     SRFGDDRFFRQESAKMLAITLFGLQGTTYIYQGEEIGMTNAYFTKIDEYDDAESKNAY
                     YHMIKSGIDEKEALLILQQKSRDNARTPMQWDNTIYKGFSNHKPWLKVNNDNISVENE
                     LNDSRSVFYTYQRLIKYRKQYDIFTEGTYRLLDENHKNLFVYEREYKNQNLLVISNFT
                     HDNVVYKLPETYLNKLNYTILETNYTRDIIENKMEIKPYESIMIYYK"
     gene            complement(23471..24790)
                     /locus_tag="OE968_000828"
     CDS             complement(23471..24790)
                     /locus_tag="OE968_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCP7218141.1"
                     /translation="MEKGIKLGFWSIVLLGINAIIGSGIFGLPGDAYTDIGPASILVL
                     VFCMLLAVSIALCFAEAGSWFDTDGGPYLYAKEAFGDFVGFEVGFMKWIVSMIAWATM
                     ANFFAVTLSSVWPQAAEPLIKNIIIGILVVGLGIINFMGMKQSKHLNNIMTIGKLLPI
                     VLFIAVGLFFIKGSNFTPFVIIQKGQSASSAFVAVSITLFYAFTGFESLAVAAKDMEN
                     PKKNVPKALVMVMFVVSVIYMLILGISIGVLGNGLAGSATPVADAAIKMLGPIGGYII
                     TIGTIVSVGGINIASSIFTPRSAAALVEQGLMPKSIRQTNKNGAPYIAIIVSVIGTLL
                     IAWSGSFTTLSQISVVSRFIQYIPTCLAVLILRKKYAGKDVNFRIPGGAIIPIFAVII
                     SILLLIKAGIDEPMKIVWGLGGMIIVVPIYFYMTKVYSKKYNDVEVK"
     gene            complement(24831..25577)
                     /locus_tag="OE968_000829"
     CDS             complement(24831..25577)
                     /locus_tag="OE968_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HCP7218142.1"
                     /translation="MKKLAKKKYPIIGISGNLLIDEGGMFPGYERAYVNNDYIQSVVM
                     CKAIPYIVPIVYDDEIIKEQVSNIDALILSGGQDVNPLIWKEEPHNKLGAISPKRDSF
                     DMKLLKHALDMKKPVLGICRGEQIINVTEGGSLYQDLSLIEGAYIKHNQQHLSNVPTH
                     TVQIKEGTKLYEILGEKEVLVNSFHHLVVNKVAPGYIVSATSKDGLIEAIEKEGSEFV
                     IGIQWHPEMMTRDYDNMKKIFMAIVKEASK"
     gene            complement(25821..27830)
                     /locus_tag="OE968_000830"
     CDS             complement(25821..27830)
                     /locus_tag="OE968_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HCP7218143.1"
                     /translation="MKTIAVVTDGLSKLECFLNKNLEMIFKDKVMIKNYYLNKITEKE
                     LIKDDIILVMIDDRVLKIKKYVEDVSKIITINRSIKQKDIYKLFSLPEGIDVLVVNDN
                     KHTVLETISNLYNIGINHLNFIPYNPNEEYRNIKIAITPGESSLVPKYIEEVIDLGHR
                     YIDSSTFIQIIAKLKLDDKEITERLIKYTDEIISLYSGINTKYKELTIKADELNSIIN
                     LSNLGMAMVSDKGNIIICNNSLRDILDIQSNIIGKNIDELENENIKKIFSLSKAHDEV
                     IKFNNKYLNVNKYNIESFGRVTGYYFCIQEITYIRKLEQNLSKKLREKGQVARYTFDD
                     IKTVSTKMERTKKLGMKIAESDYTILITGESGTGKELMAQSIHNASPRHSQPFIAINC
                     AAMPENLLESELFGYEEGAFTGALKGGKKGLFEQANNGTIFLDEIGDMPIYLQSKLLR
                     VLQENQVMRVGGENVIDIDVRVIAATNKNLLEMIKGDRFRADLYYRINVLPINIPPLR
                     ERKEDIEVMLKHFMKRKRAISQDVQDIINAYEWPGNIRELKNTAMYINIMSSEDVILI
                     NDLPHNLLNITEDFSKEISILKDRTSIEKVKLVMECLKNANNLNKNIGRNGIVNSINE
                     LGYNITEGEVRGILNMLKELDLIICESGRKGSELNRRGKNILNSI"
     gene            complement(28224..29657)
                     /locus_tag="OE968_000831"
     CDS             complement(28224..29657)
                     /locus_tag="OE968_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HCP7218144.1"
                     /translation="MALRKDFLWGGATAANQCEGAWNLDGKGPSCSDMCTGGSQKVSK
                     RITRVIEKGTFYPSHEAIDFYHRYKEDIALFAEMGFKVFRFSIAWTRIFPTGMEKEPN
                     EAGLKFYENVIDECLKYNIEPLITISHYEIPFAITEKYNGWVSRDVIDLYMNYCETIF
                     KRYKGKVKYWLTFNEINSATMPMGGYLSQGILNEGTTDFINQVDIPQLRFQGLHHQFV
                     ASAKAVKLAHEIDSNYQVGCMQIFATMYPYTCNPDDAVKTQRDSRVMNYFCGDVQVRG
                     EYPTYMNRYFGENNIEIKMEKGDLEILKEGCVDFYTFSYYMSTCVSSDSKEDNTSGNI
                     LGGVKNPYLKSSEWGWQIDPEGLRYALNEIYDRYRIPMMVVENGLGAYDKKESNGVIN
                     DDYRIEYLKAHIEQMKEAVEDGVDLFGYTPWGCIDLVSASTGEMAKRYGFIYVDKYDD
                     GSGDLSRIKKKSFDWYKQVIESNGERL"
     gene            complement(29744..31660)
                     /locus_tag="OE968_000832"
     CDS             complement(29744..31660)
                     /locus_tag="OE968_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HCP7218145.1"
                     /translation="MRKYEQLSKEIIANVGGKDNISSLSHCITRLRFKLKDESIANDD
                     VLKKMDGIVTVMKSAGQYQVVIGNHVPDVYEVVCDLAGLGGDTIDNSDSDAPKGLLNK
                     FIDIISGVFQPILGVLCAAGMIKGFNAVFTALGLYGETDGAYIMLNAIGDAMFQYMPI
                     ILGYTAAKKFKLKPFIGMLIGAVLCYSGIQLDTLASTGQPLYNLFTGTIFESPVYITF
                     LGLPVIAMNYTSTVVPVILIVLLAAKLEKVFAKIIPDVVKNFFVPMAVLLVSLPLGFM
                     VIGPIATYASNIVGNGFLALFNFSPILCGALTGLLWQVLVIFGLHWGLVPIAMSNLMT
                     MGFDTILVGVFVPSFAQTAVVAAMYFKLKDKKIKELCIPAVISGICGVTEPAIYGITL
                     PRKTPFIYSCVGGAVAGAVMGIMNVKSYVMGGLGIFGIPNYINPTTGDMKGVYATIIA
                     IIVAIVVGFVLTLFFWKDDAIVEISKDDNGQGVIEKNKREVVYSPIKGEVKALEQIQD
                     AAFSTGILGKGVAITPKEGKVVAPFDGTVMTLFPTKHAIGIISDNGCELLIHIGLNTI
                     QLEGKYFKSFVNQGDKIKKGQTLITFDIESISKEGYCLETPVVVTNYSDYVDIVENTQ
                     KHVNNSQKLITVLA"
     gene            complement(31734..32594)
                     /locus_tag="OE968_000833"
     CDS             complement(31734..32594)
                     /locus_tag="OE968_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HCP7218146.1"
                     /translation="MIIEKILNNNVIITTDENHKEIVVMGRGLAYKKRTGEHISKDKI
                     DKIFKLSDPNISDKFKELIADIPIRYMELSDEIILYAKEKLGKRLNDSIYISLTDHMY
                     TAIERAREGVSVKNVLLWDIKRFYKSEFKIGLEALDYIEKKFEIRLSEDEAGFIALHI
                     VNAQMDQSIKTIYEITQIIQEISNMVKYHYRIVFDEDSVYYHRFITHLKYFAERIVSN
                     NLHENNEDDLLNVIKVKYKNAYKFIEKLDEFIHKKYNYDLTDEEKLYLTIHVERVVSK
                     SIKSDINPNN"
     gene            complement(32945..34132)
                     /locus_tag="OE968_000834"
     CDS             complement(32945..34132)
                     /locus_tag="OE968_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HCP7218147.1"
                     /translation="MIESIKKRAYEIENELGKEIEEVCNFIFNNPELGEEEYISSKYL
                     VEKMKEYGFDTVYPYCNMETAFRAELGDNDGPTIAFLAEYDALPGYGENKEPAHACGH
                     NWIAASTLGACIVLSKLKENFKGKIVLIGTPAEETTGGKCDLVKAGAFDDVDVSYQMH
                     IEAFNNINCKALAIDSLEFSFEGVSAHAASHPHMGVNALDAVQLTFAGINALRQHVKS
                     DVRIHGIVSNGGEAPNIVPEKAACKFFVRAAERSYLDEVTKKVINCAKGAELMTGAKL
                     SYRYFENSFDNIINNKVLQKITKNNLIEAGITDILEGKDGPVGSTDIGNVSQVCPTMY
                     TEIALDISPMVYVHEKEFLNYANSEEAYDKLHKAVKAMVGCALEIYLEDGLLDEIKKN
                     HLN"
     gene            complement(34146..35537)
                     /locus_tag="OE968_000835"
     CDS             complement(34146..35537)
                     /locus_tag="OE968_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HCP7218148.1"
                     /translation="MSSLKKKKFTMPQTLTIIFLLIVLMAILTWIVPSGNFERVDIDG
                     RSVVVAGTYEKAPSNPQGITDVFTAPINGFIDAAEVVGFVLIVGGAFGIVNKTGAIEA
                     VIAHTVNKMKKFQFLIIPISMILFGLGGTTFGMSEETLPFYMIFIPLMTSMGYDSLTA
                     VATVFIGATAGFGAATTNPFSVGIAQALSQIAPGSGIEFRVVMFIIYMAISIGFVMMY
                     ANKVKKDPKKSLVHDISLNQESMVNSDTNIKEFTKREAMVIAIFTIGMAIMIYGVLKL
                     GWYITEIAMIFTAIGIISGIASGLKQDDIVNSFISGAGDLMTAGLCIAFARGIVIIAE
                     NGFIIDTILNSAANLLNGLPKTIFINLTFLIEGLIAFLIPSASGLASLTIPVLAPLGD
                     LVDVSRQMIVTAYQFGIGVTNLITPTSGVLMGALAVANIPWSKWVRFVIPLMVVLTIL
                     VMAFLTIGLYLGF"
     gene            complement(36132..37832)
                     /locus_tag="OE968_000836"
     CDS             complement(36132..37832)
                     /locus_tag="OE968_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HCP7218149.1"
                     /translation="MHYIAWHFNKNGGNNTMKDKLQVLSGAMMIPVILLVVAGVFIGL
                     GSAFANMENVSALGLSGLIKEGSFINVFFKVINDLGFMVMRYLPIFFVTGIAFGLSKK
                     EKGWGALGGIVLFIGMHTVISTLLAANGINSDTVTAEAFMASGLGEAEAYSRSSLYGS
                     FLGIFSYDCSIFGAIIAGFVASAVHNKFVDIELPSALSFFSGPRFSMIMMFIASIVLG
                     TAMYFIWPPVGLALSKLGNWIGSSGLLGTFTFGAMDKALLPFGIHHLIAFPIEYTRVG
                     GTMEVGGAIYEGVNNIRLAQMGDPDTLSYITRNFTTGRLLIHFAILPAAALAMYKLAD
                     NANKKKAISILIPAIVTAMLVGVTEPIEYTFLFVAPLLYFVAYVPLAGLTYVFTEMFN
                     VSIMGESFRNMFPNLLQPQKVDALPLLFLIPIFFIVTYIIFTWAIKKFDIKTPGRSSE
                     EVKLYSKKEYRERQSVDAGKTAYNNAVEEEVDDKDTKLVHSIIEGLGGSNNIKNVTNC
                     ATRLRVELNSIDGFYEDGFWVNELGASGVVKKKNSVQVIFGPRVITIASKLKAVLGVD
                     "
     gene            complement(37804..39207)
                     /locus_tag="OE968_000837"
     CDS             complement(37804..39207)
                     /locus_tag="OE968_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HCP7218150.1"
                     /translation="MIVNKELIIDYLKSNQENIINDIRSLVEIPSIRDESTTDINQPF
                     GIEIRNAFDKLIQIAKDKDFVVKDFDGYAIHIEYGEGEEVVGVLNHIDVVPIYNKELW
                     KSKPFKVCQKDNYLYGRGVNDNKGPLIGILYALLFLRELNEKPKRKIRLIVGGAEETT
                     WECMEHYFSVNEQPKFAFSPDGNFPIVNGEKGILYFNLRKKIDKDKFRNHNLVDIKSN
                     KEDGFVCDKIEAVFKTNDKKDLVESLAYYTEIEELEEGKVLVRYTGERALSRNPHRSY
                     NCAFSLAKDLEKIKKLNDKGVIIRDILNSYFTDDNHGKKLGIYKEDVDMGVSTICIMS
                     IFLEKNELNMKIDFRYPKGISWEFITNRINEIGKKENLIVDIYKDLKLLYVKPDSELI
                     NKLSNAYKQGFGKEAELFTKGAASYARVLKNGVAFGPTIEGDNPNSHQANENISIDTL
                     YKAIEVYIYALYSLAFQ"
     gene            complement(39471..39962)
                     /locus_tag="OE968_000838"
     CDS             complement(39471..39962)
                     /locus_tag="OE968_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HCP7218151.1"
                     /translation="MFNIFKKKENKIEKIYSPFKGNLVNLEDVPDAVFAQKMMGDGVA
                     IIPSEGKLYSPVDGEIVNVFDTKHAIMIKSNDNTNILIHVGLETMSLEGKPFDVKVKA
                     GDKVKAKDLIMEVDLDFITSNDLNIITPVVIMDDADSVKRTVKDRIEPGNVDINSIIM
                     EVE"
     gene            complement(39988..40800)
                     /locus_tag="OE968_000839"
     CDS             complement(39988..40800)
                     /locus_tag="OE968_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HCP7218152.1"
                     /translation="MRYKLICTDMDGTLMGKGFEVSEENIKALKEVMEKGIKVALVTG
                     RPYNAMKYFTSVLGDDIYIISTNGTYFKLLGYEYKKVLSKEALKKIYTIGEKYNLSKH
                     FKGCKIVISNNEIGEEHPYRLINSKNKEEDRIEIIENASCETLLEKADNEILKCILFS
                     ENVDSLREAKEEFKKQEDLEVVSSGKINFEVMSKGTSKGIAVKKFCDILGIDSKEVIC
                     IGDNENDISMIKFAGLGIAMGNATDEVKSMADFVTDTNVNDGVAKALRKILS"
     gene            complement(40813..41964)
                     /locus_tag="OE968_000840"
     CDS             complement(40813..41964)
                     /locus_tag="OE968_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HCP7218153.1"
                     /translation="MINFYQPSRINFGQGTLSELPRIIGKYGKKCLLVTTPNVEPLDK
                     LYKRVTLNLIEKGIEVVHFDRVEPNPTVELINEGFELAKKESVDVVLAVGGGSSIDTA
                     KVLALTFGLEKIDWDYMFSTYTNPFKIYDKVSEKELPLIAVSTTSGTGSQVTQAAVIS
                     RGSEKNTIFHQNCFSKECIVDPELMLTLPERITASTAFDAFTHAFESYINPNANDFTE
                     IMSEKSMELVINYLPKVMEDKNNIEYRTKLAVADTLGGSSLANAGAAAPHPLSEIIGG
                     VTHIPHGEALAIVFPKFAEKFYKDNIEKFAKVARMLNQELEKVEDDEAAKTLGNEIES
                     FLKRVGLKTKMSEFNVTKEQLEQITSCPVLGFLPFGKKEDLVEILEKSY"
     gene            42234..42875
                     /locus_tag="OE968_000841"
     CDS             42234..42875
                     /locus_tag="OE968_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldolase"
                     /protein_id="HCP7218154.1"
                     /translation="MKYLIDSANLDEIQKCLKYGFKGITANPSMYLKEKVNFHEFIET
                     CANLNPEILTAEVIGNNLYELINSCDKILNINKNTIIKINFSEVGLELINILNSKGVK
                     TACTLIFNVNQASLAINAGADYLFPFIGRNDENGNDGIKNLTEICNLISINGYNTKVV
                     AASIKNVFHLTQASLCGCDYAAVTYDLFKKASFNQLTIDGANTFERDWSKVNK"
     gene            42901..44445
                     /locus_tag="OE968_000842"
     CDS             42901..44445
                     /locus_tag="OE968_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HCP7218155.1"
                     /translation="MNKRLLDIAELLLNSSDYITVDTIAEELKVSNKTIRNDLVILDE
                     WLLEFNLSLDKKTGSGVIILGNEDIKLKVIRDINDKSNCIYAYSPEDRKRYILSKLFI
                     KNSKFRIRDICNELHVSRATVHKDLVVIQNFLQNFKVTLVRKTNNGVYLEGKEKDIRK
                     AIFELATVNKSYTELKEILFSKSNECKDTPSTKIFKELFNYDFEKLSQITLHTLQVEK
                     SNLSDEYYINFLIHIAICIKRISIKRYINLSEGFFRELLEHEYFEKSKILCANLSEAF
                     DVEFIDEEVCYILLHIEGLLKSIKKTTTLEPLKNEEITEYNLSEAIAVHWGSILNLNL
                     KDDLILIKSLANHLKSVLHRINYGFTITNPILNDIKRTFPYTYKAAKESNTVIKQLMN
                     YEVNDDEIGYLALYLISAIDRSKSPLNTILICHCSDGVSNLLVQKLSFEFNQINIVKS
                     IPLSSISFTNFDDVDLILTTAPVDFEHNAELININALLSKNDISRLSTIIKKLYSEKN
                     KILSYK"
     gene            complement(44645..45271)
                     /locus_tag="OE968_000843"
     CDS             complement(44645..45271)
                     /locus_tag="OE968_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HCP7218156.1"
                     /translation="MKKEMIKDYLLITISAFLMALAVNFFFAEHTLAPGGITGLSVVL
                     STFLSMPVENISLGISMPLLVMGLLFLGKGFGIKTLYITLMGPLFLKVIPQTHITDNL
                     LVAGVIGGLLVGTAIGIAIIRGCSTGGTDLVAMLINKVIKFLKLPVILFMLDGFIIVA
                     SGIISKNFMISIYSLISLLLIIKTIGFVTTKFGKNTEEINNINNACAQ"
     gene            complement(45406..46122)
                     /locus_tag="OE968_000844"
     CDS             complement(45406..46122)
                     /locus_tag="OE968_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentose-5-phosphate 3-epimerase"
                     /protein_id="HCP7218157.1"
                     /translation="MKHIKIAAGLAHVNYGHISAVVKEAMDAGVDYVHSDAADMHDLK
                     NMQLMGGHQIIEAIRPVTDKPIECHIYTRDCDRLFIEKIAAAGCNLLIIPAEHFLGAP
                     LAYIINYCREFGMKVGLTIGCYTPLCFVDEAIYDIDRLQIVVHGVDETDGKDNWGWRK
                     SAVDLVKRARKMIDEKNPKCELAIDGGLRADNMEPLIECNPDVVILSSAIFKDKDGIT
                     AGVKNCRKAIDKAATKFGLE"
     gene            46548..47762
                     /locus_tag="OE968_000845"
     CDS             46548..47762
                     /locus_tag="OE968_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HCP7218158.1"
                     /translation="MRNCIIAQSGGPTAVINASAVGIYEKNLETKYFDKVYFGINGIE
                     GILNKNIIDSDSLNKDNVLNLKQTPSSGLGSCRYKLADYKINSYDYDRVINILDEYEI
                     DTLFYIGGNDSMDTVMKFSQYCKNTTCKIKFIGIPKTIDNDLLGTDNCPGFGSAAKLI
                     STLIMETYLDFSIYKNNGIFIVETMGRDTGWLAASSSLARLNDTPLVDLIYLPEIDFY
                     EDKFIEDVRKIFKEKNKAYIVASEGIRDKYGNFICEQKTSAHDKFGHSQLGGVSNYLK
                     NLIVSSSITTRVKTLELGVIQRCAMHLASDTDLKQAAEVGAYGIELSKKGYTGVMAII
                     NRTCNNPYKYEVSHTDISKIANKTKYFPKEWINEECNYITDEALNYLYPLIQGKPDIK
                     YKNGLPYFSIIY"
     gene            48382..49710
                     /locus_tag="OE968_000846"
     CDS             48382..49710
                     /locus_tag="OE968_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218159.1"
                     /translation="MMKIAVITTEFLKEFVDNSIKKLNINAEIEIYIYRDFSHVGDLY
                     LEIEDRFDGFAVSGPIPKKAITKKAGTIKKPLVDFGTDLQSYYDMFLKLIFKYNTLDF
                     SRAYFDLTDWADNPKDISYYLSNGTFGDLMDSIDENASKMSLSDIAKLEKKIAKKHIN
                     LWNEGKIDFSTTRFSSIVPMLQNAGVNFHFIYPDIDLLKNTFNNLIKDIHLHRMKGNQ
                     PSVIYITVKDTNYDDSTLDQVYKILNSIKKDKLTDFIIEKNSNSFKIFTKCETIKSLT
                     KNFTACYIKESIENSTNIKVCVGYGIGNDIKQAMSSAISANKESKINHLNYSFLVNEN
                     YETIGPLLCDKLLTVSNKVTPHINTIAKSSKLSTLTIQKIISVTEILQRDEVTPKELS
                     SCLNVTVRTANRFLSSLLKSGNATILYEKQNSTKGRPERVYKLFISENKY"
     gene            complement(49838..51028)
                     /locus_tag="OE968_000847"
     CDS             complement(49838..51028)
                     /locus_tag="OE968_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HCP7218160.1"
                     /translation="MKNFFKEAQSIEGEIIRWRRYLHENPEIGCNLPKTVTFVTSTLE
                     KMGYSPKLTSNNGIVAVLDSKNGGKTLLLRADMDALPIMEETDLPFKSKNKDASHSCG
                     HDNHTAMLLGAAKILMDNKHLLKGRVKFVFEPDEETTRGAKSMIDDGILENPQVDAAM
                     AFHSMVGKFLNTGQVAYSRGPAMASADIFEITVEGKATHGASPEFGVDPINIMSHIQI
                     ALNTILSREKPQKEPVVLTIGMFNAGSVPNAIPNKASMSGTLRTFDQSVREKLKNRII
                     EISTGIAKSFGGNAKVEFKMGTPAVINDLDVGDEIVSYVKEVIGNENVIDFPSAMGSE
                     DFSEILLRVPGVFLWIGMGSISQGYNFGMHNPKAIFNEEGLVYGSALFAHCAVKWLEN
                     NFSR"
     gene            complement(51134..52513)
                     /locus_tag="OE968_000848"
     CDS             complement(51134..52513)
                     /locus_tag="OE968_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HCP7218161.1"
                     /translation="MIGSISINEIDKKRFKLDDLSKKIWENPEKAFKEFKACENTANF
                     LRSEGFDVEVGVGGLATAIRASFGSGKPVIGFMGEFDALPGLNQKVSTKQEAFELGAY
                     GHGCGHNLLCTAHVGAVVGLKREMIENNLSGTIVFYACPGEEQLTGKGFMARGGAFEG
                     LDLAINFHPNKISEATIGTSTAVNSVKFHFKGKTAHAGSDPQNGRSALDAVELTNVGA
                     NYLREHVTSDVRIHYTITDGGVAPNIVPDKASVWYYTRALSREAVESTYERLVKVAKG
                     AAMMTETEVEVEFLGGCYNTLNNHVLANLVSECMNEIKQEPWTREELDFAAELDRQSP
                     QQYKAMISKYNLPEGTHLYYGGGNVTNFNSYGSTDIGDVMHIVPTAYFFTGCTNLGAP
                     GHSWQFTSCAGSSIGEKGMIYASKIMAMFGAKILNNPEIAKKAKEEFDKSMNGKTYKC
                     PIPDDIPTP"
     gene            complement(52544..53752)
                     /locus_tag="OE968_000849"
     CDS             complement(52544..53752)
                     /locus_tag="OE968_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218162.1"
                     /translation="MENFWNPLTCFTVCVMIYAFSEFLSKKTKGAISTLLFVCIIFLL
                     GFWTNILPKDITGASGILAAMSNFGIALLITNLGTLINLEDLCHEWKTVVIALVGIVG
                     IGVGCLTVGSMLFGREYALIAAPPIAGSTVAGIIVTTVAEAANRPELAAFVILVLSFQ
                     KFFGIPITTYCINKELKFKRDNGDFLKDESKSNFKLPSMRIFKEDLGKKSSTLVYLAK
                     LSFVAMIGNFVGLATLIPGFTPANYYLNPNIACLLVGLIFTRIGFLEKGILDKSQSNG
                     IIMFGCMLMLPGGLAKVTPTALFGMIIPTIGILVVGSVFIILFTAIVGKLLGYSPRMS
                     AAIGVTCMLAYPATQIISNEGIDAMEGTEEEKQRATDYLLPKMIIGGFVTVTIASVAF
                     ASIIGPIIFG"
BASE COUNT        17867 a         9637 c         6139 g        20676 t
ORIGIN      
        1 tatcatatat ccatcataga agtcatctac ctggataact cttaccatat tataactttt
       61 taatattaat ttaaacttag aaagaaattt tttatttaat tatatcatct tccttatttc
      121 aaatttctca attacaatct taatcaaaaa ataaaataag atgctgtctc aaaatagata
      181 taatcttctt ttttattgtc ggaatgatga aaatatattt aatttcatac aaaaaagagt
      241 gcctcatgaa ctaaaagttc attttgagac accccttaat ttaatcttac ttattctttc
      301 cctttattat taacacttca ctatctctat tgcttttcct acacatccac aaacttccat
      361 cctactctta acaaaatctt taactgactc taaacctttt ttaccatatt ttttagggtc
      421 aattacctct gggtcagaat taagcacatc cttaacccca ttgctataag caatccttaa
      481 ttcagttgca taattaacct tgcaaatccc tctttttata gactccttaa taacctcatc
      541 tggtattcca gacccaccat gtaatactaa tggaactgat acaacctctc taatttcaga
      601 taatctatct aaatcaagtt ttggctctcc cttatatagc ccatgtgccg tacctattgc
      661 tactgctaaa gatgataccc ctgttctctc tacaaactct tttgcttcta atgggtctgt
      721 atatgctcca ccatcaccac catctaaatc gtcttcctta cctccaactt tacctaattc
      781 agcttcaaca ggtatatctg aaggcataca tgcatctaca acagatttag atattgaaat
      841 attatcttca taactttcat gagaaccatc aatcataata gaagtatatc caactctaag
      901 tgcctgcata gctagtccaa agcttgaacc atggtctaag tgcattgcta ctggaacact
      961 tgccttctct gatgctacct ttacattcgc taaataataa tctagtcctg catactttat
     1021 tgttgaaggt gttgtttgca atattactgg tgatttaagt tcttcagcag cctctattac
     1081 tgccataacc atctccatat tttcaacatt aaatgcacct actgcataat gcccttcttg
     1141 tgcatctaat aatatttgtt tagttgtcac taatgccata atttctcctc ctatatgttt
     1201 atactgattt aatttcttcg ttatttaatt ttgatactat ttctctactt gttttgctat
     1261 ttaataactc atttaaaaat tcttcattca ttaattttga agatagttga gataatgttt
     1321 ttaagtgtaa attatcacca ttatctgtag ctgctatcat aaatataata tgtgccaagc
     1381 ttccatcttc tgattcaaag tcaaaccctt cttttgatag acctactgct acacgtggta
     1441 cctttactgc atctgttttt gcatgtggta tcgctatccc cataccaaaa cctgtagatg
     1501 atatttcttc tcttttaagg atttcttctt taaacttctt tttatctaaa agaacactag
     1561 atttatcaag tattccaatc atttcatcaa ttacatctgt tttatttttt cccttaacat
     1621 ctaaaattac tgtttcttcg ctatataaag agatattatt agatacgttt tccgattctg
     1681 cactttcatt tttatgttca tcttttgtta catttgtatt ttctatagta tttttctcat
     1741 ttactacttt aggtgtaacc atcatataaa gtacagcacc tactaatgaa cctacaaata
     1801 tacaccctac ccataaaagt ggcttattga ctaatcctag aaccaaaaac cctccatgtg
     1861 gagctggtac ttctattttc attatataag ttaaaattga tgatattgat gatgcaatca
     1921 taagtactgg caacactttt aatggatttt ttgctgcaaa aggtattgcc ccctctgtta
     1981 tatgagtact acctagtata taattgatta atcctgctgc tctatcttct tctgtaaatc
     2041 tatttttaaa taaagtagat gctattgcta ttaccaatgg tggtgttata caagctgcag
     2101 atacacctgc cataaataaa taatttccct gtcctagaag catagttcca gttacatatg
     2161 ctgctttatt tactggacct cccatatcaa atgctgacat acatcctatt actattccca
     2221 aaattatagg gcttgaattt tgtaaccccg atagaaagtt catcatagca ttgttaagtg
     2281 ctgaacatgg cccaccaagt aacaacattg ctacacccac aagacctacg ctgacaatag
     2341 gaattataaa aatcgattta agaccttcta attgtcgtgg taattttctt aacaaatgta
     2401 caaatagttt aactaagtaa cctgctaaaa atcctgatat gattccacct aaaaaccccg
     2461 aacctgtatc aaatgatatc attcctccaa caagtcctgc caacatacca gctcttcccg
     2521 atatagattg agctataaat gctgccaata caggaaccat caagttcata gaatatccac
     2581 caacagattt taatgtagct gctatttgat tatattgttc tgaatttggg tcaaatgaat
     2641 aaatccccca taaaaatgat atagcagtaa gtactccacc tgctactact aaaggtaaca
     2701 tgtgagatac accattcatt aagtctttat acaacttttg accaaacgat aaatttcctt
     2761 cttctgcaat tttactgctt gataagtttc cttttctaat agctactttt ccatcaatac
     2821 atctttgtat aagttcatta gctttatgta taccttcttt gacaggtact tctattactg
     2881 gctttccatt gaatctgtcc atatcaacat ttttatcaca agcaactatt attgcatctg
     2941 ccatttcgat atcttttgct gttaacttat tttctacacc tatagctcca ttcgtttcaa
     3001 cttttatgtc acaccctaat tccctggctg aattttttaa tgcttcttct gccataaaag
     3061 tatgagctat tccagttgga caacctgtta cccctagaat cattttcttt cccattttta
     3121 taccaccttt ctgactctta tattttttat ataatcttcc acattctcca aattacctat
     3181 accattactt tcagccacac ttgctcctgt tgctgctgac ctttttaatg cttcttcaat
     3241 atgttctgga ttttccaacc atatacttaa aaaagcagct aatgcagaat caccagcaca
     3301 tgcagagctg actactgtaa ctggttgagc actagcataa taaattgatt ttccattata
     3361 aaaataagaa cctttttctc ctaaagttag caatatattt tgagcacctt ttaaatgtag
     3421 taatttaagt acatccttaa tatcttcttc atctcttaca ataattccaa atatatcttt
     3481 gatttcttca tcatttggtt ttatcaaata tggattatac tgtagtaact cctttaattt
     3541 tggtgaactt atatcgagta ttgtctttat acttttattt tcacaaattt taaatatatc
     3601 ctcatagtaa ttatcatcaa taccaggagg tagacttcca cttattgata agtaacttat
     3661 atcttctaat gactgtatct tatctagcat atctagtttt tgtttttcgt ttacatatga
     3721 cccagagttt acaaatttaa attcatcact tccatcattt aaaaatatat ttatacgagt
     3781 tgtatcttct acccaagtag gcaatacgtc aaatcctctc ttttcgcttt cttcaactat
     3841 atattttcct gaaaatcctc caaaaaatcc taatatctta gattctatac cataatgacc
     3901 tagtacaaaa gttacattta atccctttcc attaggagaa tatacagcat ttgatgtacg
     3961 atttactaat tttctcttta tcccattagt agatatattc atatctattg caggatttgt
     4021 agttaatgta tatatcattg tcttccccct tgcttgtgct gtgtatgttt tcattataat
     4081 aaaaaagtct atgaaaatct tttcacaaat agaaaatcga ttttcataga cttttcaatt
     4141 taattttcag aattattata tctgaccata taatctataa ttatcctaga tataatatac
     4201 aagggcaatc tggaagatac ttcatattca gaaattgata tatgttcatg tttgtatcct
     4261 acaatatata aatccgaata ctttataagt tttgcacttt cactacaaca gcaagttata
     4321 accttagctc caactaaatt ggcattctgt gctgattcta caagctctat tgtatttcca
     4381 ttcaatgaaa atataattat aagttcgtct ttttttattg atttagattt tattttcatt
     4441 atgttggggt catttataaa aacaacatta aaatcaagta attgcaattt aagactaaac
     4501 tcttttgcta catattcagt aagccctctt gctaaaatat atatcttact agatttattt
     4561 acagttttta ttatattgat tagtgtagtt aaagatattt gttctataac tctctgtgct
     4621 tctataaagg atttatttat tatatccccc atattttgta tatcatcatt ttcatctttt
     4681 actgttaatc tatacctaag ttcattgaat ccatttaaac cacattttct aattgctctt
     4741 gaaacggttg ctggagatga atatgtttca tgagcaatct ctactataga taattctggt
     4801 aatattgatt cattttcatt tataaattta attatttcaa gttccgtctt ggttagattt
     4861 tcagaattac ttttgtttag ctcaattatc atatgttatc tccccttata taagttttat
     4921 ttgtctaaat ttatcgagta atataatata ttacctctta actacttatt tttatataca
     4981 attaagattt agtcaatgtc tatatatgta aatttataat ataataattt tttgcttaaa
     5041 gtttattatg ttatcttata gcattttaaa ataaaaaaga attgtacctc taccaaaatt
     5101 tggatgaagt gcaatagata ttccttatac tgatatgttt atgattaaaa gtataaatat
     5161 aaatttcgct atgaatcata taattaataa atcattttat ttacaattat aacccccctt
     5221 ataaaactat attaataata tatacagtat ttataagggg ggttgtttat atttaaaaac
     5281 tatttacttt tcttttaatt cttctccatt agttcttatt acattttgat accaataaaa
     5341 actatctttt ttataacgtt ttttacttcc atttccattg ttatctatat ctacatatat
     5401 aaatccatat cttttttcca tttcttgaga tgaacaactt actatatcta ttggtgacca
     5461 catacaataa gctaatattt cggttccatc agctatagct tcacctattt gttctatatg
     5521 ttttcctaaa taatctattc tgtaactatc atgaactttt ccatcttcaa atttatcatg
     5581 cattccaaat ccattttcag ctatcattat tggcttttgg tatctatcat aatattgaga
     5641 taaagtattg tataatcctt ttgggtcaat tgcccacccc caaggatttg cttttaaata
     5701 tggattcttt atattgtcag ttggattcat ggtgttttta cttgctgata ctgttgtaga
     5761 ataatagtat gataaagcta gaaaatccat agtattttct tttaagattt tatcatcacc
     5821 ttcctccata actatattta tgttattttc tttgaaaaat ctcttaatat agactggata
     5881 ctctccccta aaacttacat cagtgaaaaa atattgtagc ctatttcttt ttaaagcaaa
     5941 tactacattt tcagggtcac aatcttctgg ataagatgta caatctgcca tcatcatacc
     6001 tatcatcata tctgaattta tttcttttcc aagcttctta gtcaaagctg tagctatgaa
     6061 ttgatgatga atagcttgat atctagtctc ttctacatta tctacttggt ctacacaaaa
     6121 tgcaactgaa ttaaatgatt cataatgtat taaatttatt tgatttataa ctatccaata
     6181 tttaacttta tttttatatc tatttagtat taattctgca tatctaacaa agaaatctac
     6241 cacttttcta ttagaccatc ctttatattt taatactaaa ttcaaaggag tctcatagtg
     6301 aagtagtgtt acaataggtt ccataccatt atctattact tcatttataa gattatcata
     6361 aaactttaat ccctcttcat taggctctaa atcatctcca tttggaaata ttctagccca
     6421 atttattgaa aatctaaaac actttaaccc tagctctttc aaaagcttta aatcttcttt
     6481 gtatgtatga taaaagtcta ttccactacg cttaggataa tatccattat tatctttcat
     6541 agcaaacttt attctttcta tagtcatatc agactcataa ggtttagata tatctctatc
     6601 tttatcatac atatgtacat cagctaaaca ccaacctttg ccaccttcat tccatgcacc
     6661 ttctaattga ttagctgcta cagctcctcc ccataaaaaa cctttaggaa acttacccaa
     6721 tttaatcact ccttatttta tttatttaaa tcatttacta ttatttacct tatattctat
     6781 agactttact attcctacta aagacatagt tatatttaac tcgctgaata tggtcataag
     6841 agtatcttga gcatgtgcaa ataacagcga atgtgctctt ttctctccac cagcttcccc
     6901 ttgtataatc ttggtttgag ctctatgtgc ttctgtcata aacccttttg ctttagctag
     6961 ttttaaatca gcatttctat aatcaaactt ttccaaatca ttaagagcat gtttaatttc
     7021 tgttctagcc tcacctgcac gaagtattat ttgcattgcc acctctacta attcttcatc
     7081 tattatatgt tcttcaattg tcatatttat aatttccttt caatttctaa atttaaacct
     7141 cttggctctc taattttatc tcttctttct cataagcttt aaaaaatgga taccatatca
     7201 taaatagcaa tactatattt attgctaaaa caataagacc tctaacatct tgatttaccg
     7261 taaaagtaga tataccaaaa ggaacatacc ataaattaaa caccttactt ggaattgtca
     7321 caaatcccat actcattgat aagtaagtag ttattgatat tactactgtt cctatccaca
     7381 taggtaacat taaaaatggg ttccatgcca ctggagctcc aaatattact ggttcattta
     7441 tattcattat agaagggaca atacatgctc ttcctattgc ttttattctt ccaactctgg
     7501 ataaacacat cattataact aatggtaatg tagcacccaa ccctcctaaa gttatccaac
     7561 ctgtttgaat aacttcgtaa acatatatat tagttgctac tcctcctgat gctactgctg
     7621 ctgcattagc tgcaattgca ccaagttgaa ttgaataagt tataggagat agtacccacc
     7681 cacttattcc taaagaatat ataaatacta ctaaaaagtt taagagtaca aatccaggta
     7741 atgtctgtgc tatatctgat actggtttaa atactctaac tattatttca aacatgtcaa
     7801 agttgagtcc ataaattaat ccccagccta caaacattat cactgttata ggtaacatat
     7861 tatcaaacca cttgcttaca aaatccggaa gtgctgaatc ttctccgaaa aatgaaaaag
     7921 aaccaaataa ggacattatt aatccagaga ataatcctgc aactagcgat acaagcattc
     7981 cttctcctcc aaacctgttg aagttaaata tagctccttc attcgtaatc tctggacgaa
     8041 tcatcattaa cattaatcca gcacctgcaa gaccagcgac tacactcata ctttcaaatt
     8101 tcttattctt cattatttcc ataggcaata aaaatgctat aaataatcct aaaagtccaa
     8161 atgtatattg atttattgga cttaaatcag gtaaaaagct tatgtaattc ttcaagacag
     8221 aaactatagt tactaatgag cctacaaata ccattggcaa aactttcatt atagttgatt
     8281 gaactgattg tacccatata ttcttagtca tattatttac aacaggagta aatttttcac
     8341 ttaaaaaatc tataaattta ttcataaaca ctctccccat aaatatttta tttgtttgat
     8401 attagttcta gtgcttcttc caaagccttt gccccatcta gtcttccata tgcagtttta
     8461 gatatacatg ctactggaac gttatattca ttagcctttt gttgaatttc ttccttcata
     8521 taatctaaat gtggtcctag taataaacaa tctatttctg ataaatactt atctatctct
     8581 gactcacttc tcgcttttat atctgcttct ataccttttt tctttgcact ctttctcata
     8641 ctagttgcca taaaacctgt acttgctcct gaaccacacg ccaaaagcac tcttatattt
     8701 ttcataatga tacctccaat atttttatcc atcaatttat ttcttaatga actttttatt
     8761 ttattatgtt tatattgtac ttaccaaata agttcatttc acataaatat atttcctaat
     8821 aataggaaat cagttactct taattaaaca tattaatata gtataatgta tcttataata
     8881 cgtacattca attatataat tatcatatca tccagatttt attttaaaac tatgcgaggg
     8941 aatctaatga aaacatctaa aaaagaacta tttttaaatt tcataaaaac acaacatgat
     9001 tggatagatt catctacatt ggctaattat cttaatgtct caacgcgttc aattagaaaa
     9061 tatgtaaacg aaattaattc caatggtgaa tttatattat cctctaaaaa aggatataaa
     9121 gtaaatctca ataataattg tcaaaccaag gttgatagtt cagaaaatat atcacctgat
     9181 aacaggttaa atttaatttt aaaagaactt atagttaata gtaatggaat taatatattt
     9241 gatttaagtg aagacttgtt tgttagtcca gctactattg aaggagatat agtcaaagct
     9301 aataaattta taggaagtta taatttaaag ataaagcaat cgaaattttt attgaaacta
     9361 attggaaatg agtctgcaaa gcgcaaatta atgagctcta taatatttaa agaaacggga
     9421 agtgattttt taagcttatt tgatgtacaa aaaatatatc aagagtataa tttgaccaaa
     9481 ctgaaagaaa atataatata tatattaaaa aaatacaatt tgtttataaa tgagtatgct
     9541 ataaataaca tacttcttca tttaatgata actatagaca gaataaaaaa gaataactac
     9601 atagaatctg tcgaagtagt aaactacata gataataata atgatataag catttcaaga
     9661 gatatatcaa attttttaga gtctgaatac aatataactt taactagtgc agaattatac
     9721 tacttagtat ttcagttaac aaacaaaacc acagtcttaa attatcatga aatggatact
     9781 aagtcattgc caaattatat agatgaacat tttgttaaat taactaaaaa aataattaaa
     9841 aatgtatatg acttatactt tatagattta tctgatgatg aatttgttgt aaaatttact
     9901 cttcatgtaa aaaatttaat cagtagggct aaaaataatc aagttttgag aaatcaaata
     9961 cctcagaagt taaaagattc ctaccctctg atatatgata tatctgttta tatttgtaat
    10021 cagattcaaa ttttagaaaa catagaaata gatgaagatg aaatatcgta tatatctctt
    10081 catgtaggtt cattttttga tagacaaaaa ttactagaag ataaaattct ctgtgcatta
    10141 attactccaa attactatga tttacaattc aaaatagtaa gagaccttga gaagagattt
    10201 aatgaatcca tagaaattat tcagattttt tcagatactc ataatcttga ttttgacaat
    10261 aaggtagaca tggttattac tactttacca attagcgata gatgccctat accttttgtt
    10321 tatgtaaatc cttacctaaa tagaaaggat tatgataata ttcaaagtaa atttattcag
    10381 attaaagata gaaaaaatat acttactgta caaaatcatt tagaaatgta ctttagtgaa
    10441 tctttgttta tgaaaaatat atatttagat agtgctaaag attatataag atttatggga
    10501 aatattctgt acgaaaataa atatgtcaaa cccaattata tagatgatgt tcttataaga
    10561 gaaaaaatgt cttcaactgc atttaataac aatgtagcaa ttcctcatag catgaaaatg
    10621 gatgctttaa aaaccggagt atgtttaatt gttaacgata aaccagttaa atggggtgag
    10681 gaaaaagttc aaattatagc tatgatacct ataaatgaaa aagaaaaaga aaagttcaat
    10741 tacatatttg aaagctttat tgaaatatta tctgagtgga ataatgttaa agaacttact
    10801 aaggcagata actatagtag ttttatgaat agaatagctt atcttattca aaatatctaa
    10861 atcaattaat ttatttccaa tatatgtttc ttaagttatt aacataaaat agataagctg
    10921 tcacactaaa aagtctaaat taatatgtga cagcttttta cctaatatac cttgttttaa
    10981 tactacatat tttttgactg ttgtatacta gttataagat tgaatatttg tgttgttgta
    11041 gctgtcatat tctcactagc agttgcttta tccattgctt cttctattgt catagctcta
    11101 tttactatag aaaaataagc atctataccc tcttcattac atttaactgc atcttctgtt
    11161 gtggctccag ccaaacctat tacttttacc ccatattttt ttgccagttt tgcaactcct
    11221 attggagcct tgcccatagc agtttgattg tccaatctac cttcaccagt tatgacaaaa
    11281 tctgcatctt ttaactcttc ctctaattta atttcttcta atattatttt tattccagat
    11341 tctaattttg aatttaaaaa tgctaaaaaa gcaaaaccta atcctcctgc tgctcctgct
    11401 ccttctacat tagctacatc tttacttaag taatttttaa ctactttgga aaaatttcta
    11461 agcccattat ctaactcctc aattatttct gatgttgcac ctttttgaga cccgtatatg
    11521 tatgcagctc catttttccc aaacagcgga ttatttacat cacaggctat tttaaactta
    11581 cattcatcta attcctttaa tctattttct atttttatat gtcttatttc atttaaaact
    11641 tttccaccta atcctactaa cttgttattt tcatcataaa actcaaaccc taaggcttga
    11701 agcataccta tcccagcatc attagtagca cttccaccta tcccaactat aaaatttcta
    11761 tagcctttat ttattgcttc ttttattatt tccccaacac cataagttgt agtgtataaa
    11821 ggatttctaa gttcagtcgg aaccaatgtt agtcctgatg cttgagctat ttctattatt
    11881 gctgtacttg tattttttaa taatccatat gttgcatcca cttttttagc tattggtcca
    11941 gtaacttcta tagtatcttt tttaccattc atcccttgaa ctaaggcatc tactgtccct
    12001 tcaccaccat cagcaagtgg caatatcttt acttgcgcat cttctttaac cttcaatatc
    12061 ccctttttta ttgcatttcc tgcctctatt gaagataagc ttcctttcaa agaatctata
    12121 gaaattaata ttttcatatt tatctactcc tttttattac tccttatttt aaacatataa
    12181 ttttataagc ttaatttatc ttttatttta tactctacat ctctctttgt atacaactta
    12241 taccattaat attcttttat cttataaaaa gggagtgtct caaaataaat ttcttagttc
    12301 atgagacact ctttttgtat aaaatcaaat atatgtttat tatttcaaca atgataagga
    12361 ggattatctc tattttaaga taattccttt ttagcactat ttaaccagta tagttttaac
    12421 ttggttcatt aagcactcta catttacaga gttattatct attgatatag attctaattc
    12481 tttttcattt aggttaatcc atttagctgt tttaatattt ttgttaaata ctatgttagc
    12541 tgattttgtt tcttctttag aattgtaaaa tctaactact aatgcctctt gtttttcagc
    12601 cttttttaca acacttaaca caaggtcctt attagtttcc ttaagtaaac tatatgaata
    12661 atctacttct atttctgatt gattcaattt catagcatta tatggcattt tattataagt
    12721 ttgtattttt gttaaatact ctttagccat atttgcaaca tttgcttcta gtgtagattt
    12781 ttcatgagta actattgcta agtctatttt tatatctcct atcatttgag aatctggagt
    12841 aggcaacttt attcctgatg gacgacctgg gcgtcttgcc atttcttctt tacctaggaa
    12901 tcctacactt ctaaataatg ttatagctat tgtgtcaaat ttttccccta ctatttcaaa
    12961 ctctcttgta ctgtttgtaa gaacagctac tccatgctct ttgtcagaca atccaacgaa
    13021 tgttagcatt ggatatatag aatctggtct ttcactccat tcttcctgtt gccaaacttc
    13081 catagcatca tcatacacac ttctctttat atgtccaaac tgattatcag acacagaaaa
    13141 ctttgaagct atatttgttg gtatataagt tctaacccta caatctcttg cttggttatt
    13201 tatgttgaat actacatcta ttatagcttt atcatttgga acatttataa ctatatcaaa
    13261 gtcaataaat gaatctgctc tattattttt tctagcttgt atatcttttg gtacttttaa
    13321 tctataattt atctttatct cattattaaa tctatttttc tttatagtgg aatttgctac
    13381 tatattatcg ttaaatatta atttctcatt tggaagtggt gaaaaatcat actcatctcc
    13441 ttcatctcct ccattttcca tcaataatac attttcaaaa gttttattta attttttatc
    13501 aaatatcttt aatgtcccgt tttcattaac ttgaatagta taaaagtcat tatctaccat
    13561 gtcacatact tcataagctt tttctaacat atgttcaact tcttttatca tatacgcctt
    13621 ataccccatt gcaggtattt tatctttaaa gtttattgta tataccataa atgaatcata
    13681 gtttccataa tgaacaattt gacggtctat taatcctgca tctattactt ctttatgtac
    13741 cacttcaaaa tccaacttat tattatcttt atcaaatatt tcaaatgctt tcattttagt
    13801 tataacttga gcgcttacta tttcattcct atcgtaaggc attaagttaa atgctactaa
    13861 cttatctaaa gccatttcac aactcattgc atcaactatt cttcttttgt aaaatgttat
    13921 taattggtct actttttcct cagctaagaa aaatctattc attatttcat ggtgaacttt
    13981 atctgaacaa caacatccaa tgctgtcatg agcatgattt ttcattattt ctttccaaat
    14041 taactctatt aatccatgat gatattcaaa tcctagagaa tatgcaatag aagctagtgg
    14101 ctccaatatg ttggttatct ttgattctat tctagcattt gctgatttta tatccattct
    14161 tgttgagaat atacttctat gaaccctcat atatttccca tctaaaaatt ccccttttat
    14221 tgtatctata tcctcatttt tttctagctc tttaaatatg ttttcatatc tacttaagaa
    14281 aaattttctc tctggataac attcttttaa tttatatata acttcaaata tattcttttg
    14341 aattggcatt tggtcatgtc catttggaag tattatatgg tcagtagttg cacccttatc
    14401 aagaaccggt aaatatttat ccattcttgt tcttagctca tcttcattca ttggtagata
    14461 ttttcctatt gcataaccta atggaagtat ttgaaccaaa acagaagacc catcatcact
    14521 cttccaatta aactctgttt tattagttcc ttttctttca gaacatcctc tccaaaacat
    14581 tgagtatttt atatcaaacc catttagtat ttgtggcatt tgagcacttt gaccaaatga
    14641 atctggtaaa tatcctattt tcatatattc tccaaattca tcacaatctt ttattccata
    14701 tagtaaattt ctaagtatgg attctccacc aactaccatt tcatcagttt gagtatacca
    14761 aggacctatt attagccttc cttcttgaac taattttttt attctctcct tacattcagg
    14821 cttaactgct aaataatctt ctaatatagc agtttgacca tccatcacat aatatggata
    14881 gttatgatta ttttctaaca tatccattat ttcttccata ttatttacaa gtaatattct
    14941 agattcctca gttgagaagt accattctct atcccaatgc atatgaggaa ctatgtgtac
    15001 attttttttc attgcttatc ctccaaaact tatctgataa tattttctgt ctaattaaaa
    15061 atccaataaa aatactactg agtttacaaa attttttaat atttatttta tcactataat
    15121 taaacctttg atttaaatat ctaataacgt atcttttaat gtatctttct ttgatttttt
    15181 tgtttcctag ttattattaa taatactgct gatattatag ctccaagtac tgccgcaaag
    15241 aaccatattg atgctataat aaatcctgac atacttccct ctaaaagcgc caatgagaat
    15301 atccccgctc caggcacttg aagacctata ttgaagaatg ctactataga cccagttatg
    15361 gctgaaccag ctaccaatga tggtataaca cggattgggt cctctatcat aaatggtatt
    15421 gcaccttcag ttattccagc caatcctaat atccaagttt gctttcctat ttccttttct
    15481 gattctgaaa ataaatctct gcctaaaaca gtagctattg taactccaaa agctgaaacc
    15541 atcttaactg atgcaaatat tgcataaggt ataaaatttc cacttgctat tgctcctatt
    15601 gcaaatgtat aggctgcttt atttattggt ccacctaagt caaatgaaac catagctcct
    15661 attattgcac ctagtagtat tgcatttact ccagtcatcc catttaacca atttataaga
    15721 ccattgttaa gtgctgctac aggctttcct actacaaata acatcaataa acctactacc
    15781 aaagaaccaa ctactggata tacccaaaaa cttacgaatc cagctaatgt gcctttggct
    15841 ggtatattct tctttaaaaa ttttactata taaccagcaa gtaaacctcc taacatacct
    15901 ccaagaaatc cactacctat taaatcagct gctagacctg ctgcaaatcc tggtccaaga
    15961 cctggttttt cagctagtga gtaagacata tatgctgata atactggaac catcaatgta
    16021 cctaacatac ctccagaaag ctttcttaat tgccataacc aagaaccttc ttgattgtat
    16081 agttcttgta gaccaaatgc ttgagatgct aatactgcaa atgcaagtat catacctcct
    16141 gccacaataa gtggtattat atgagatact cctgtaagta ttgctgattt tacatctttt
    16201 ttccatgatg atttttcaca atatgatata tcagatgatt tttctatata atcaccttta
    16261 ccttgttttt gtgctacttc taaagcttcg tatattattt cttttgctct ttttagtgga
    16321 gctgctactg acgtttttat gtttggcaaa tgttcaaatc tttctgtatt tttaggtgct
    16381 acatctgttg catatattat tgcatctgcc ctttttatta tatctggtgt atgagggtcc
    16441 accataccat tagctccttg cttttctaca tacacatcca caccgatttc tttaccagct
    16501 ttaattaatg cttctgctga catatatgta tgtgctatac ctgcagggca tgctgttatt
    16561 gctaatataa ttttttttga ttcattttga atcctaatct cttcttttat ttgttctttc
    16621 ttttctttta tatctaagtt attaaataac tctttcttag tttttgaatt taacaacata
    16681 ttcatataat cttcatttga cagtctagta actaactcag aaagtatttg tatgtgtgta
    16741 tttccacctt cattttctgg tactgctatt aaaaatatta tctctacttt attatttggg
    16801 tctacgcttt cccaattttc tattggtgtc tctaaggtca tagctgcaaa tgcagcttct
    16861 ttaactgact tagattttcc atgaggaatt gcaagccctc tttcaaaacc tgttggagat
    16921 aaagtttctc tgtacattac agcttctaaa tattcctcat aagatgttaa cttgccttca
    16981 tcatatagct ttcttgctaa gaactttatt gcgtctttct ttgtttttat tttttgtttt
    17041 aaaaaaacaa ggttttcatt tgtgattttc ttaaattcca aaattacgcc ctccttaaat
    17101 catttaatgc tatgaatata gcataaaata aattatgaaa atgttttttt gaaattatac
    17161 acacaatttc ttcttaaaaa ataaagattt gtgtatttat acacaaatct ctatcttaac
    17221 cagtattgct ctattattgc tctcataatc atcataattg gaaccttatc tgatatattg
    17281 tacccattta cttgtttaat tgttgaatag caatataaac ttatatctgc aatttgttgc
    17341 aattgatttt cacatatatg tgttagagct actaccttac aacccttatt aactgctgtc
    17401 tttgctactt ctataacttc tttcgtttct ccacttaaac taagtgcaaa aaacatatct
    17461 tgttcaccta attttcctat atcatgaagt acttcatgtc tttgactata gtaagttata
    17521 ttatcatgcc cacctctaat ttcttttact aatatctcac ataaaggaat gttttgacct
    17581 attccataaa ctataatact cctagatttt tgaattatat ctgctacttt atttattttt
    17641 tcataatcta ttagctctaa tgtctttttt atatctgatt caaaaccatt ttttggctct
    17701 ttatcctcat tttttaactc ttcttttaaa ttatttttta gttgagagaa accatcatac
    17761 tccatttttt tacatagcct aactatggta tttgggacag taaaaaattt atctgctaaa
    17821 gattgtattg ataattttac tatttcttct ttgttttttc tcatatattc aattatcatg
    17881 tcttctgtat ctgtaaattt atactcatat ttttttgctc tttcataaaa ttccatagtt
    17941 tctcctccat ctattttatt attcataagt aaaattcaaa aatattagct aaaattttcg
    18001 ttaatataat tataatttaa tatttttaat ttattaatgc atactactct ttttattata
    18061 cataaaaaat gtgtacttcc tatattgata gagatgattc aagtttttat tttgatacat
    18121 ctctatcaat atttttttag aaaatacaca tttttttcaa atacttattt ttaattaaaa
    18181 ctttaggtaa tctattcttt atatataatt attagacttg aaaatatctt taaaatcaac
    18241 caattcaata ttatttcttt ttaaccacat tttaacttcc ttatcacata gcattgcatg
    18301 ttcatatact ctctcttgaa taagagaaga tgattttata agactataat ctataaatcc
    18361 tggatgagta accatcaatg ttatatcttt atctaaattt atatattttt cttcaaataa
    18421 tttaacaaaa gatttattta acttgtaaaa atcattctga ggatatttac ttggcatgct
    18481 aatacatgaa tccaaataat agggacaact tggtataccg tattcttttg cagcatcaca
    18541 cattgctgat attgatacat cttcttctat accatgtata tcaatatact caggcaattt
    18601 actcatatac aacttgtaag tttcaatttg agcacaaact tcttcatata cttcttcata
    18661 attaaaaacc tctttacctg tcagtagttg cgttcttctt attttgctag aaacaaattt
    18721 tccaccttca tctaacaaat tctttatctt aatatgttct ttgcaacaag gttctcctat
    18781 tactaaatta acatgtaaac caaaacatac atcatcattt tttaccattt ctatagcttg
    18841 tcttgaaaaa ggcatattca ccatgattcc agcacttgta acaataccgt tcttataaga
    18901 agatattatc cctagtgtaa caccttctga atatcctata tcatctgccc taactactag
    18961 tttcttcatt ttatgcgtct gcctgctttc tcaactcatc aagttgcatt tccatctcat
    19021 cctttacttt aacaacatcc gttcctatga tgatttgaac tgatgtatta ctcaatttaa
    19081 ttaccccttt ggctcctgtt tttttaatat tatcatcatt caaaatagta gcatccttca
    19141 cttctaaacg taatctcgtc atacaattat taagagtcac tatattttca taaccaccac
    19201 aatttttaat tatctgttta gccatatatg aaaaattacc atgagaaagt tttaaattct
    19261 tttctttttc actaacttta tcacctatct ctatctcaac ttcacgtcct ggtgtttgca
    19321 cattatcttt tattattata tatttaaatg ttacataata taatacaaag aatacaactc
    19381 ctacaggtat aactaaccac gctttatctc cataactaaa acttaagaca tagtcaatta
    19441 tacttgctcc attaaatgaa cccaagcgaa cacccagtaa atatagtaca actccaccta
    19501 gaccagaata aaaagaatga attatatata actttggaga tgcaaataaa aacgaaaatt
    19561 ctattggttc agttactgtt gccataaaag aagtcaatgc tccagcggtc attgcacctt
    19621 ttacttcttg cttcttttta tcttgtgctg ttttatatat agcataagaa atagcaggta
    19681 ttgaaaacat cataattatg taaaatcctg tccagaagaa tcctgcattt gggtctcctg
    19741 ccataaatct aggaatttct cctcttataa cttctcctgt tgatgttgta tattcaccca
    19801 tttcaaataa tatgtaagca tttaaaactt gatgtaaccc agttggtatt agtgcacggt
    19861 tacagaataa aaacaagaat attcctattg caccagctcc tcccaaccaa aaaccaaatt
    19921 gattcattgc agcttgtgga tatatccata ataaactaaa tatatatgat aaaattaaag
    19981 caaccactgg tgatagtgta attacacatt tttctcctgc aaagaagctt aaaaatgctg
    20041 gaactttaac tttatatgtt ttattgtaag tccatgctat acaagctcca acaattatcc
    20101 caccaaatac acctgcattt aatgtatcat tcaataactc taaatttgac ttaaatatca
    20161 tatatgcaac tacggctgca accattacac ttgtcttgtc tttagacttt gagtaggcac
    20221 tagctgctcc taataaaaat aagtagtcca catttgaaaa tactatatta gatatattag
    20281 atatagctgg cacattgagc atatttggac caaataataa tcctaatata cctgctgctg
    20341 gcattacagc tattggcact agcatagtct ttcctaaaag tgacagttgt tgcatcattt
    20401 tgtttaagaa cctcttcata tccaatcccc tttctatttc ggtttaattt tttgtgaaaa
    20461 cgatttattc acattttata ttttaaatat tatatttgtt taaacaaatt gtcaatattt
    20521 tttattcatt ttatttttat catttagttt aacatataaa tccttttaag tgtattgcta
    20581 tatctagtct atttttttaa ttcatttttt ttattttaaa aatatgttta accatgtatt
    20641 tgaaacaacc cacaaaataa ttctattttg tcctttttat ggttgatatg attctatttt
    20701 cactatacat gtctaaacac atttgatata atttgttcat atcagttcaa taatattact
    20761 aaagaccttt aaggagggat aggggtatat ggctaaaaat aaattttcag agatatatga
    20821 agtattgaaa gaggaaatac ttgatggtaa atatacaagt aatatgatgc tgcctactga
    20881 acttcaactt attgaaaggt tttcatgtag cagaaacact gtacgtagag caatttctca
    20941 attaaacaca gaaggatatg ttcaaagtat aaaaggcaag ggtgttgtag tgttagaaaa
    21001 tagttgttct aatgattttt ttctaaatat gcacaatttc aaaggtgtag aatcgattgt
    21061 agaagataaa aaggttaata ctgctactag tgttctccac ttcagcaaaa tcttaattga
    21121 taataagtta tctaaaaaga caggttttaa agttggtagt gaagtatatt accttcacag
    21181 actaagatat attgataaca tacctaaaat tctcgacatt aactattttc tatgtagtat
    21241 agttaaagac cttgatgttt ctatagcaca aggctctatt tataaatata tagaagagtg
    21301 tctaggtaca aaaattgttt catccagaaa gatatttaaa attgaaaaag ctacagagct
    21361 tgagttaaaa acgctacctc taaatgatta taattgtgtt ggtgttatta aaaatagtgt
    21421 atatactgat gatggaaagc tttttgaata tactgaatca aagcatacac ctgaaacatt
    21481 tgtattcatg gatgttactc aaagatatta aaaaaattat gtttaattaa acataatttt
    21541 tttacgttta gacactttat cccatactaa cctcactatt ctatatacaa ttatgtgttt
    21601 atacaaataa ttatttattg tatattttag ctttaatatt agtttaatgc ttgacaattt
    21661 gtttaaacat attataatta acttataaat tacaggaggt atcaattatg aaaaattggt
    21721 ggaaaaaagc aactgtctat caaatatatc caaaaagttt caaagatagc aacaatgatg
    21781 gtataggtga tataaatggt attatagaaa aattagatta tctgtattat ttaggtgttg
    21841 atttattatg gttgactcct atgtacgttt ctcctcaaag agataatgga tatgatatag
    21901 aagattatta taatatagac ccaaaatatg ggacaatgag tgactttgaa aaactcttaa
    21961 aagaagctca taaaagagac ataaaaataa tgatggatat ggtcctaaac catacatcta
    22021 ctgaacataa atggtttaaa gaatctaaaa aaagcaaaga caatccatat cgtgattatt
    22081 atttctggaa agatgctaaa cctgatggtt ctgttcctaa taactggata tccagattta
    22141 gtggaactgc ttggaaatat gatgaaacca ctaaccaata ttatttacat ttatttgaag
    22201 aaactcaagc tgatttaaat tgggaaaatg aaaaggttcg tgaagaatgt tacaaaatac
    22261 tagaattttg ggctgataaa ggtattgatg gttttcgttt agatgtagtc aacctactct
    22321 ccaaaacacc tggattacct gatgacccta taacaggacc aaaaggagat ggaagaactc
    22381 actacgctga tggtcctcgt atacacgaat atttacataa tatgaatcaa aaagttttca
    22441 aacctaaaaa tatagttact gtaggtgaaa tgtcatctac tacacctgaa gagtgtatca
    22501 actatactag agaaaatcga gaagaactat ctatggtttt tagcttccat catatgaaaa
    22561 cagattataa aggaggcgca aaatggacta atgaaatgtt ctctctggat aaattaaaaa
    22621 aagcacaatc tgactttcaa tataaaatgt atgaaggaaa aggatggaat gctctatttt
    22681 actctaatca cgaccaacct agagctttat ctagatttgg agatgataga ttttttcgtc
    22741 aagaaagtgc taagatgtta gccataacac tatttggtct acaaggtact acatacatat
    22801 atcaaggtga agaaataggt atgacaaatg cctactttac taaaatagat gaatatgatg
    22861 atgctgaaag taagaatgca tactatcata tgattaaatc tggtattgat gaaaaggagg
    22921 cattgcttat acttcaacaa aaatccagag ataatgcccg tactcctatg caatgggata
    22981 atactattta taaggggttt tctaatcata aaccgtggtt aaaagttaat aatgacaata
    23041 ttagtgtaga aaatgagctt aatgattctc gttcagtatt ttatacttat caaagattaa
    23101 tcaaatatcg taaacaatat gatattttta cagaaggtac ttatagattg ttagatgaaa
    23161 atcataaaaa tctatttgtt tatgaaagag agtataaaaa ccaaaatctt cttgttataa
    23221 gtaatttcac tcatgataat gtagtatata aattacctga aacttatttg aataaattaa
    23281 actacacaat acttgaaacc aattacacta gagatataat tgaaaataaa atggaaataa
    23341 aaccttacga aagtataatg atatattata aataaagtta tttatgtaaa aataggtata
    23401 acaccctggt gttataccaa ttttactaaa ttcaaagtaa tgtttataga atatctatag
    23461 attacaataa ttatttgact tctacatcat tatatttctt tgaatatact ttagtcatat
    23521 agaaatatat aggaactaca attatcatcc cacctaatcc ccaaactatc ttcataggtt
    23581 catcaatacc tgcttttatc agtaataata tacttataat aactgcaaat attggtataa
    23641 ttgctcctcc aggtattcta aaatttacat ctttaccagc atacttcttt ctcaatatta
    23701 gtacagctaa acatgtagga atatattgaa taaatctaga tacaacactt atttgagata
    23761 atgttgtgaa tgaacccgac catgctatta gtaaagttcc tatgacagat actataattg
    23821 ctatataagg agctccattt ttattagttt gtcttataga cttaggcatt aatccttgtt
    23881 caaccaaagc agcagcagac cttggtgtaa atatggatga tgcaatattt atacctccaa
    23941 cagatactat agttcctatt gtaattatat acccacctat aggacctaac atcttaatgg
    24001 cagcatctgc aacaggagta gctgaccctg ctaagccatt acccaacacc cctatactta
    24061 ttcccagtat aagcatatat attactgata ctacaaacat taccattacc aatgctttag
    24121 gtacattttt cttagggttc tccatatctt ttgctgcaac agctaaagat tcaaatcctg
    24181 taaaagcata aaataaagtt atagatactg ctacaaaagc tgatgacgca ctttgacctt
    24241 tttgtattat tacaaatggg gtaaaattag aaccctttat aaagaataat cctacagcta
    24301 taaataaaac tattggtaat aattttccta tagtcatgat attatttaag tgcttagatt
    24361 gtttcattcc cataaaattt ataatcccaa gccctacaac taatatacca attattatat
    24421 ttttaataag tggttctgct gcttgtggcc atacagatga tagtgttaca gcaaagaaat
    24481 ttgccatagt agcccaagca atcatactaa ctatccactt cataaatcca acttcaaatc
    24541 caacaaaatc tccaaatgcc tcttttgcat aaagataggg ccctccatca gtatcaaacc
    24601 aactacctgc ttcagcaaaa cataaagcaa tagaaacagc taaaagcata caaaaaacta
    24661 atactaatat acttgctgga cctatatctg tataagcatc accaggtaac ccgaatatac
    24721 ctgaccctat tattgcattg attcctaata gtacaatact ccaaaaacct aacttaatgc
    24781 ctttttccat tgttattccc cccaaagcca acttaatata tttgtatttt ttatttagat
    24841 gcttctttaa ctattgccat aaatattttt ttcatattat cataatctct agtcatcatt
    24901 tctggatgcc attgtatccc tattacaaac tcacttcctt ccttttctat agcttcaatt
    24961 aaaccgtctt tagatgtagc tgaaacaata tatcccggtg ctactttgtt gacaactaag
    25021 tgatgaaaac tattaactaa aacttctttt tctcctagta tttcatataa ttttgtcccc
    25081 tcctttatct gtactgtatg tgtaggtaca ttagatagat gttgctgatt gtgtttaata
    25141 taagcacctt caattaaaga taaatcttga tacaaactac ctccttcagt tacatttata
    25201 atttgttctc ctctacatat acctaaaact ggttttttca tatctaaagc atgttttaat
    25261 aatttcatat caaaactatc tctctttggt gatattgccc ccaacttatt atgaggttct
    25321 tctttccata tgagtggatt tacatcttgt cccccagata gtataagcgc atctatatta
    25381 gatacctgct cctttataat ctcatcatca tatacaatcg gtacaatata tggtatagct
    25441 ttacacataa ctactgattg tatataatca ttatttacat aagccctttc atagccagga
    25501 aacattcctc cttcatcaat tagtaaatta cctgatattc ctattattgg atatttcttt
    25561 ttagccaatt tcttcacccc ttaacttatt tgtgaacaat aaaaaatgct acttctctta
    25621 aagagcaagt agcataccaa gattttattt atttgaacat tataatttat tttagaaata
    25681 ctttttttga atacgagtaa tataaataac tttatttact tatattttat tttaatcctg
    25741 tttagtttga cttttttaaa ttgttttaag tacaactaat aggtaaaata ggcatttaga
    25801 ttttcctttt tatcaaccta ttaaatactg tttaatatat tttttcccct tctatttaat
    25861 tcacttccct ttctaccaga ttcacatatt atcaaatcca gctcttttaa catattaagt
    25921 attcctctta cctcaccttc tgttatattg tagcctaatt catttattga attaacaata
    25981 ccatttctac ctatattttt attaagatta ttggcatttt ttaaacactc cattactaac
    26041 tttactttct ctatagatgt tctatccttt aatatgctta tttctttact aaaatcttca
    26101 gttatattta ataagttatg aggtaaatca tttattaaaa taacatcctc agaactcata
    26161 atgttaatat acatagcagt attttttaat tctcttatat tacctggcca ttcatatgca
    26221 ttaataatgt cttgaacatc ttgactaatt gctctcttcc ttttcataaa atgctttaac
    26281 ataacttcta tatcttcttt tcgctctctt aaaggtggta tatttatggg caatacattt
    26341 atcctatagt ataaatctgc tctaaatcta tctcctttta tcatttctaa taaattttta
    26401 tttgtagccg caattactct aacatctata tctattacat tttctcctcc aaccctcatt
    26461 acttgattct cttgtaatac tctaagtaat ttgctttgta agtatatagg catgtctcct
    26521 atttcatcca aaaatatagt tccattgtta gcctgttcaa ataatccttt tttacctcct
    26581 tttaaagctc ctgtaaaagc accttcttca tatccaaaaa gttcactttc aagtaaattt
    26641 tctggcatag ctgcacagtt tattgctata aatggctgac tatgtcttgg tgatgcatta
    26701 tgaatagact gagccatgag ttcttttcct gttccacttt ctcccgttat aagaattgta
    26761 taatcagatt cagctatttt catacctaat ttcttagttc tttccatctt cgttgaaact
    26821 gtttttatat catcaaaagt atatctagca acttgtccct tttctctaag cttctttgat
    26881 aggttttgct ccaattttct tatgtaagtt atttcttgaa tacaaaaata atatccagta
    26941 acccttccaa aactctctat attatactta tttacgttta agtacttatt attaaatttt
    27001 ataacttcat catgtgcctt actcaaacta aaaatctttt taatattctc attctctaat
    27061 tcatctatat ttttccctat aatattactt tgaatatcta gtatatccct taaactatta
    27121 ttacaaataa ttatgtttcc cttatctgat accattgcca tacctaagtt tgataaattt
    27181 attatggaat ttagttcatc tgcttttata gtaagttctt tgtatttagt atttattcct
    27241 gaatataaac taattatttc atctgtatac ttaattagcc tctcagtaat ttctttatca
    27301 tccagtttga gttttgctat tatttgaata aacgttgaac tatcaatata cctatggcct
    27361 aaatcaataa cttcttctat atattttgga actaaacttg actctcctgg cgttatagct
    27421 atcttaatat ttctatattc ttcattggga ttgtatggta taaaattcaa atgatttatt
    27481 cctatattgt ataaattaga tattgtttcc aatacagtat gcttattatc gtttactact
    27541 aatacatcta ttccttctgg caatgaaaat aacttatata tatccttttg ctttatgctc
    27601 ctatttatag ttattatctt tgagacatct tccacatatt tttttatttt taatactcta
    27661 tcatctatca ttaccaatat tatgtcatct tttattaatt ccttctctgt tattttattt
    27721 aaataataat tttttatcat tactttatct ttaaagatca tttctagatt tttatttaag
    27781 aaacattcta atttagacaa cccatcagtt actactgcta ttgttttcat ttgattactc
    27841 cttttaaaat atactctact cttttataat atacatttga ttttcacttt aataacacaa
    27901 aaaattgtac atttagtata ctaacatatt cctttattag ttttatgtcc ataaatatca
    27961 tagttgcaat atctatcata tttcttaaac ttctataaag caaaaattgt gccaaattaa
    28021 taattttctt aattttattc taaagttcct caatagtatt tacagactta gcacttatag
    28081 cttataagtc tttatattat taatctattt ttataggtta attgtacaaa tcatatatca
    28141 cttttaccta ttaaatgcat tataaaaaat tgtatttata aacactattt actactcttc
    28201 taagtacaaa cagtatctac atactataac ctttcaccat tagattctat tacttgttta
    28261 taccagtcaa aactcttttt cttaatccta gacaagtctc cacttccatc atcatactta
    28321 tccacgtata taaacccata tctcttggcc atctcaccag tagatgcact tactaaatct
    28381 atacatcccc atggagtata tccaaataaa tcaacgccat cttctacagc ttccttcatt
    28441 tgctctatat gtgcttttaa atactctata cgatagtcat catttatcac tccattagat
    28501 tcttttttat cataagctcc taaaccattt tcaactacca tcataggtat tctatatcta
    28561 tcataaattt catttagtgc atatctaagc ccttcagggt ctatttgcca tccccattca
    28621 ctagacttaa gatatggatt tttcactcca cctaatatgt tgccacttgt attatcttct
    28681 ttagaatcac tacttacaca tgtagacata taataactaa atgtataaaa atctacacaa
    28741 ccttctttta aaatttctaa atctcctttt tccattttta tttcaatatt attttctcca
    28801 aaatatctat tcatataagt tggatattcg ccacgcactt gtacatctcc acagaaataa
    28861 ttcattactc tactatctct ttgagtttta actgcatcat ctggattaca agtataagga
    28921 tacattgttg caaatatttg catacatcca acttgataat ttgaatctat ttcatgagct
    28981 aacttaacag ccttagcact tgctacaaat tgatgatgta acccttgaaa acgaagttga
    29041 ggtatatcta cttggtttat aaaatctgta gtcccttcat ttaatattcc ttgtgataag
    29101 tagcctccca taggcattgt agctgaattt atttcattaa atgtcagcca atattttact
    29161 tttcctttat atcttttaaa tattgtttca cagtaattca tatacaagtc tattacatct
    29221 cttgaaaccc atccattgta tttctctgtt attgcaaatg gtatttcata gtgagatatt
    29281 gttattaatg gttctatatt atattttaaa cattcatcta tcacattttc ataaaattta
    29341 agtcctgctt catttggttc tttctccatt ccagttggaa atattctagt ccatgctatt
    29401 gaaaatctaa ataccttaaa tcccatttct gcaaataaag ctatatcttc tttgtatctg
    29461 tgataaaaat ctattgcttc atgacttgga taaaatgttc ctttttctat aactctcgtt
    29521 attcttttac ttactttttg agaacctcca gtacacatat ctgaacaaga aggacctttc
    29581 ccatctaaat tccatgctcc ttcacattga tttgctgctg ttgctccacc ccataaaaaa
    29641 tcttttctaa gtgccataat tctacctcca ataatttatt tatagtaact ttattttaaa
    29701 ataaaaatac atatatataa ttcttaatta atagaactct cttttacgct aaaacagtta
    29761 tcaatttctg actattattt acatgctttt gtgtattttc tacaatatcc acataatcag
    29821 aataattagt aacaactact ggtgtttcta agcaatatcc ttcttttgaa atactttcta
    29881 tgtcaaaagt tattaatgtc tgaccttttt taatcttatc cccttgatta acaaaagatt
    29941 tgaaatattt accttccaac tgaatagtat ttaaccctat atgtatcaat agttcacaac
    30001 cattatcaga tataattcct attgcatgtt ttgttggaaa taaagtcatt acagtcccat
    30061 caaatggtgc cactactttt ccttctttag gtgttattgc tacacctttt cccaatatac
    30121 ctgttgaaaa cgctgcatct tgtatctgct ccaaagcctt tacttcacct tttattgggc
    30181 tatatactac ttctcttttg tttttttcta taacgccttg cccattatca tctttagaaa
    30241 tttctactat agcatcatct ttccaaaaaa ataatgttaa aacaaatcct actacaatag
    30301 ctactattat tgctattata gttgcataaa cacctttcat atctccagtt gttggattta
    30361 tataattagg tataccaaat attccaagtc cacccattac ataacttttt acattcatta
    30421 tccccattac agctcctgcc acagcaccac ctacacaact atatatgaat ggtgtttttc
    30481 ttggtaaagt tattccatat attgcaggct ctgttacacc acatatccct gaaataactg
    30541 caggtataca cagctctttt atcttcttat cttttaattt aaagtacatt gctgctacta
    30601 ctgctgtttg tgcaaaagat ggtacaaata ctcccactaa tattgtgtca aaccccatag
    30661 tcataaggtt tgacatagct attggtacta atccccaatg tagaccaaat attacaagca
    30721 cttgccacaa taaaccagtt aatgcaccac ataaaattgg tgaaaagtta aataaagcta
    30781 aaaatccatt tccaactata ttagaagcat aggtagctat aggccctata accataaatc
    30841 ccaatggtaa agaaactaat aaaactgcca ttggtacaaa gaaattcttt actacatctg
    30901 gtattatttt agcaaacact ttctccaact tagctgctaa taatactatt aaaattactg
    30961 gtactactgt tgaagtgtag ttcattgcta ttactggtaa tcctaagaaa gttatatata
    31021 ctggtgattc aaatattgtt ccagtaaata gattgtataa aggttgacct gtagatgcta
    31081 gagtatctaa ttgaatacct gaatagcata aaactgcacc tataagcatt ccaataaatg
    31141 gttttaattt gaatttctta gcagctgtat atccaagaat tattggcata tactggaaca
    31201 ttgcatctcc aattgcattt aacataatat atgcaccatc agtttctcca tacaaaccca
    31261 atgctgtaaa tactgcatta aatcctttta tcataccagc agcacacaga actcctaata
    31321 ttggttgaaa aactcctgat attatgtcta taaacttatt aagtaatcct tttggcgcat
    31381 ctgagtctga attatctatt gtatctcctc ctaatccagc caaatcgcac acaacttcat
    31441 aaacatctgg aacatgatta ccaataacta cttggtattg acctgcactt ttcattacag
    31501 taactatacc atccattttt tttagcacat catcatttgc tattgactca tcttttaatt
    31561 taaaacgtag cctcgttata cagtgagata aactgctaat attatccttt cctcctacat
    31621 tcgcaatgat ttcttttgat agttgttcat actttctcat tttttctcct ccattttctt
    31681 tttgaaatat gaaggtttgg ccaacttaat gtcaccaccc aatatatata aacctaatta
    31741 ttaggattta tatccgactt aatactttta cttaccactc tttcaacgtg aatagttaag
    31801 tataattttt cctcatctgt taaatcgtag ttgtattttt tatgtataaa ttcatccaac
    31861 ttttctatga atttataagc atttttatat ttaactttta ttacatttaa taaatcatct
    31921 tcattatttt catgtaaatt attactaaca attcgttctg caaaatactt taagtgagta
    31981 ataaatctat gataataaac tgaatcttca tcaaatacta ttctgtaatg gtatttaacc
    32041 atatttgaaa tttcttgtat tatttgtgta atctcatata tagtttttat actttgatcc
    32101 atttgtgcat taactatatg cagtgctata aatccagctt catcttctga tagtctaatt
    32161 tcaaattttt tttctatata atccaatgcc tctaacccta ttttaaattc actcttataa
    32221 aatcttttta tatcccaaag taatacattt tttacactta ctccttcacg agctctttct
    32281 attgcagtat acatatggtc tgttaaagaa atataaatac tatcatttaa tcttttccct
    32341 agtttttctt tagcatataa aattatttca tctgataatt ccatatatct tataggaata
    32401 tctgctatta gttctttaaa tttatcagat atatttgggt ctgaaagttt gaatatctta
    32461 tcaattttat cctttgatat atgctctcct gtacgttttt tataagctaa acctctcccc
    32521 ataactacta tttccttatg attttcatca gttgtaataa ttacattatt attgagtatt
    32581 ttttcaataa tcattgtgat gcccccttta ttagcattaa gttaaaataa atctttttta
    32641 attatttaga atatttaaaa tgtaatttat tacataaaaa aaaacctatt tattacacat
    32701 taaatagact cccatgagtc ctgagtaata aataggttta gcttgtattt aaacaatcac
    32761 tatccgtttg tattttattt taattattat ttattatatg ttagcaaatt tattttttag
    32821 tgtcaacttt ttctcaatat tttaatttta aataaattat ataaattgaa tcttcaaagt
    32881 actattttta tcaataaaca aaataaaaaa ggtattactt tctttaagta atacccattt
    32941 atttctaatt taagtggttt ttcttaatct catcaagtag tccatcttct aaataaattt
    33001 ctaatgcaca tcctaccatt gcctttactg ctttgtgaag tttatcataa gcttcctcag
    33061 aatttgcata atttagaaat tctttttcat gaacatatac cattggactt atatctaagg
    33121 ctatttctgt atacatagta gggcaaactt gacttacatt acctatatct gtagaaccta
    33181 ctggaccatc tttaccttct aatatatctg ttatacctgc ctcaatcaaa ttattctttg
    33241 ttatcttttg aagtactttg ttatttatta tgttgtcaaa agaattttca aagtatctat
    33301 aagaaagctt agctcctgtc attaactctg caccttttgc acagtttata acttttttag
    33361 ttacttcatc taaataactt ctttcagcag ctcttacgaa aaacttacaa gctgcttttt
    33421 ctggaactat atttggagcc tctcctccat ttgaaactat accatgtatt ctaacatctg
    33481 attttacatg ttgtcttagt gcatttatcc cagcaaaagt aagttgtact gcatctagtg
    33541 cattgactcc catatgaggg tgactagctg catgtgctga taccccttca aaactaaact
    33601 ctaatgaatc tatcgccaaa gccttacagt ttatattatt aaaagcttct atatgcattt
    33661 gataacttac atcaacatca tcaaaagctc ctgccttaac taaatcacat tttcctcctg
    33721 ttgtttcttc agctggtgtt cctattagta caatttttcc tttaaaattt tcttttaact
    33781 tacttaatac tatacaagct cctagtgtag atgctgcaat ccagttatgt ccacaagcat
    33841 gagctggttc tttattttct ccatatccag gaagtgcatc atactcagct aaaaatgcta
    33901 tggtaggtcc atcattatct cctaattcag ctctaaaagc agtctccata ttacaatatg
    33961 gataaactgt atcaaatcca tattccttca ttttttctac taagtatttt gatgatatgt
    34021 attcttcttc ccctaattca ggattgttaa atataaaatt acaaacttct tcaatttctt
    34081 ttccaagttc attctctatc tcataagctc tcttctttat actctctatc ataatttacc
    34141 tcctactaga atcctagata taatcctatt gtcaaaaatg ccattacaag aattgttaat
    34201 actaccatta aaggaattac gaatctaacc cactttgacc aaggaatatt ggctactgct
    34261 agtgctccca ttaaaacacc tgatgtaggt gttatcaagt tagttacacc tataccaaat
    34321 tgataagctg taactatcat ttgtcttgat acatctacta agtcgccaag tggtgcaagt
    34381 acaggtattg taagtgatgc aagccctgat gctgatggta ttaaaaatgc tattaatcct
    34441 tctattaaga aagttaaatt tataaatata gtttttggta atccatttaa taaatttgct
    34501 gcagaattta aaattgtatc tattataaat ccattttctg ctattattac aattccacgt
    34561 gcaaatgcta tacacaatcc tgctgtcatt aaatctcctg ctccacttat aaatgaatta
    34621 actatatcat cttgtttaag acctgatgct atacctgata ttatacctat agctgtaaat
    34681 atcattgcaa tttcagttat ataccatccc aactttaaaa ctccatatat cataatcgcc
    34741 atacctattg tgaaaattgc tattaccatg gcttctcttt ttgtaaattc ctttatattt
    34801 gtatcactat taaccattga ttcttgattt agtgatatat cgtgtactaa agatttttta
    34861 gggtcttttt taactttatt ggcatacatc ataacaaatc ctatagatat agccatatat
    34921 attataaaca taacaactct aaactctatt ccagaacctg gtgctatttg tgataatgct
    34981 tgtgctattc ctacagagaa aggattcgta gtagctgctc caaatccagc tgttgctcct
    35041 ataaatactg tggccactgc tgtcaatgaa tcatatccca tactggtcat aagtggaata
    35101 aatatcatat aaaaaggtag tgtctcttca ctcattccaa acgtcgtccc acctagtcca
    35161 aatagaatca ttgaaatcgg tattattaaa aattgaaact tcttcatttt atttacagta
    35221 tgagctataa cagcttctat agctcctgtt ttattaacta tcccaaaagc tcctccaact
    35281 attaaaacaa atccaactac ttcagcagca tctataaacc cgtttatagg tgctgtaaat
    35341 acatcagtaa ttccttgtgg atttgatggt gctttttcat aagttccagc tacaacaact
    35401 gaccttccgt ctatatctac tctttcaaaa tttccacttg gcactatcca agtaagaatt
    35461 gccattaaca ctattagcaa aaatattatt gtaagtgtct gtggcatagt aaactttttc
    35521 ttttttaaac tgctcatttt taatctcccc actttttaaa ttaaatattt tattattgca
    35581 tccctttatc ctattttgta tagatgtaaa aaagctcaac atggatacat gttgagctaa
    35641 atgtgctaaa tacaacatac ctgcatcttc cctttatctt gtttaagata gctctccatc
    35701 aaaattcggg ataattttga tgacagtact gtacctatta aatacagtcc cagcactagc
    35761 ttcggacact agcacttcgg cacttactcc ttttatattg cctcattggt ttccaacctc
    35821 ttcaatatta atcttagtaa atgcaacctc tacctcaatc tgtttgttag atgaggtaat
    35881 tcttattaat ttttattaat tcaaagtaat tgtagcataa tatgtcgaga ttgtaaatat
    35941 tttcagtata ataattctta ctttatgatt tcattccatt tttcacaaat aattttttct
    36001 ccatataatt taaatactgt agtatatttt aaatacacac aaactttcca caaattttaa
    36061 attattataa tacctttata ataaaaaata aaagctatgt aaacttatca atttacacag
    36121 ctttatatac attaatctac tccaagtaca gctttaagct ttgatgctat tgtaataact
    36181 cgtggaccaa atataacttg aactgagttt ttctttttaa caactccact tgcacccaat
    36241 tcatttaccc agaagccatc ttcatagaat ccatcaattg aatttagctc taccctaagt
    36301 ctagttgcac agtttgtaac attttttata ttattacttc ctcctaaacc ttctattata
    36361 gaatgtacaa gctttgtatc tttatcatct acttcctctt ctactgcatt gttgtatgct
    36421 gttttaccag catctacaga ttgtctttct ctatattctt tcttactata aagcttaact
    36481 tcttctgaac ttcttcctgg tgtttttata tcaaacttct tgattgccca tgtaaatatt
    36541 atataagtaa ctataaaaaa tattggtatc aaaaataata atggtaacgc atccactttt
    36601 tgtggttgta ataaattagg aaacatattt ctaaatgatt ctcccattat agaaacatta
    36661 aacatttctg taaatacata cgtcaatcct gccagtggta catatgctac aaaatacaat
    36721 aatggtgcaa caaataggaa tgtatactct attggttccg ttacccctac caacatggct
    36781 gttactattg ctggtatcaa tatacttatt gcttttttct tattagcatt atcagccaac
    36841 ttatacatag ctaaagctgc tgctggtaat attgcaaaat gtattaataa acgacctgtt
    36901 gtgaagttac gagttatata agatagtgta tctgggtctc ccatttgagc taatcttata
    36961 ttattaacac cctcgtaaat tgctccacct acttccattg ttccacctac tcttgtatat
    37021 tctataggga atgcaattaa gtgatgtata ccaaatggta ataatgcttt atccattgct
    37081 ccaaaagtaa atgttcctaa taatccacta gaacctatcc aattaccaag tttagataat
    37141 gccaacccta ctggtggcca tataaagtac attgctgtac ccaatactat tgatgctata
    37201 aacatcataa tcattgaaaa tcttggacct gagaaaaaag ataatgcact aggaagttct
    37261 atgtcaacaa atttgttatg tactgcacta gctacaaatc cagctattat agctccaaat
    37321 atactacaat catatgaaaa gattcctaag aaagaaccat ataaagaact tcgactatat
    37381 gcttctgcct ctcctaatcc agatgccata aacgcttctg ctgtaactgt atctgaattt
    37441 ataccatttg ctgctaacaa tgtacttata actgtgtgca ttcctataaa taaaacaatt
    37501 cctcctaatg caccccatcc tttttccttt ttagataatc caaaggctat acctgtaaca
    37561 aagaatattg gtaagtatct cattaccata aatcctaaat cgtttattac tttaaagaat
    37621 acatttataa atgacccttc ttttattagt ccgctaagcc ctaatgcaga aacgttttcc
    37681 atatttgcaa aagctgaccc tagtcctata aatactcctg ctacaacaag taatataaca
    37741 ggtatcatca ttgctccaga aagtacttgt aatttatcct tcatagtatt atttcctcca
    37801 tttttattga aatgccaggc tatataatgc atatatatat acttctattg ctttgtataa
    37861 tgtatctata cttatatttt catttgcctg atgtgaattt ggattatccc cctctattgt
    37921 gggtccaaat gcaactccat tttttaacac tcttgcataa gatgcagctc cttttgtaaa
    37981 aagttcggct tcttttccaa aaccttgttt atatgcattt gataatttat ttattaattc
    38041 actatctggt tttacataca gtaattttaa atccttatat atatcaacta ttaaattttc
    38101 tttttttcca atttcattaa ttctattagt tataaactcc caacttatac ccttaggata
    38161 tctaaagtct attttcatat tcaattcatt tttctctaag aagatactca ttatacatat
    38221 tgtagaaact cccatatcta catcttcttt atatatccct aatttttttc catgattatc
    38281 atctgtaaag tatgaattta aaatatccct tattataacg cctttatcat ttagtttttt
    38341 aattttctct aaatcttttg ctaaactaaa tgcacagtta tatgacctgt gtggatttct
    38401 cgataaagcc ctttctcctg tatatcttac taatacttta ccttcttcta gttcttctat
    38461 ctctgtataa taagctaatg attctactaa atctttctta tcattagttt taaaaacagc
    38521 ctcaattttg tcacatacaa atccatcttc tttgtttgac tttatatcaa ctaaattgtg
    38581 atttctaaat ttatctttat ctattttctt tcttagattg aagtataaaa tacctttttc
    38641 tccatttact attgggaagt ttccatctgg agaaaatgca aattttggct gttcattgac
    38701 actaaagtaa tgctccatac attcccaagt cgtctcttca gctccaccca ctatcaatct
    38761 aatctttctc ttcggctttt cattaagttc tcttaagaaa agtaatgcat ataaaatccc
    38821 tatcaaaggt cctttgttgt cattaactcc tctaccataa agatagttat ctttttgaca
    38881 tactttaaaa ggtttactct tccaaagttc tttattatat attggcacca catctatatg
    38941 attaagcacc cctactactt cttctccttc tccatattct atatgaattg catatccatc
    39001 aaagtctttt acaacaaaat ctttgtcttt tgctatttga ataagcttat cgaaggcatt
    39061 tcttatttct atcccaaatg gttgatttat atctgttgta ctttcatctc taattgaagg
    39121 tatttcaact aaacttctaa tatcatttat gatattttct tgattggatt ttaaataatc
    39181 aataattagt tctttgttta ctatcatctt aattatttat caccccttta tattaatttt
    39241 acaaagcatt tcagttcata tctacattat aaattttgaa tattattttt tcaatatttc
    39301 aaatacttct ctaagttacc ataatgatac ggtaaacaat caacagatta tgacaaaatc
    39361 atactatacc tattactaat attttaactt atctattacg tcttttttaa tgtaagttta
    39421 ttccaaaaat acataaaaaa agatgtagcc ttagctacac cttcttatat ctattcaact
    39481 tccattatta tgctattaat atctacattt ccaggttcta tcctatcttt tactgttctc
    39541 ttaacagaat cagcatcatc cattataact acaggagtta ttatatttaa atcatttgac
    39601 gttataaaat ctaaatctac ttccattatt aaatctttag cttttacctt atctcctgcc
    39661 tttaccttaa catcaaacgg ctttccttct agtgacattg tctctaaacc tacatgtatt
    39721 aatatatttg tattatcatt actcttaatc attattgcat gctttgtatc aaatacattg
    39781 actatttcac catcaacagg agaatataac ttaccttcac ttggtattat tgctactcca
    39841 tctcccatca tcttttgggc aaaaactgca tctggaacat cttctaagtt cactaaattt
    39901 cccttaaaag ggctatatat tttctcaatc ttattttctt ttttcttaaa tatattaaac
    39961 ataacacact ctccacatta taaaatttta tgataatatt tttcttaaag cttttgctac
    40021 accatcattt acattagtat cagttacaaa atctgccata gattttactt catctgtagc
    40081 atttcccata gcaataccaa gacctgcaaa tttaatcatg gatatatcat tttcattatc
    40141 acctatacaa ataacttctt tgctatctat acctaatata tcacaaaatt ttttaactgc
    40201 aatacctttt gaagtacctt tactcataac ttcaaagttt atctttccag aacttactac
    40261 ttctaaatct tcttgttttt taaattcttc ctttgcttct ctcaaagaat ctacgttttc
    40321 tgagaaaagt atacatttta aaatttcatt atcagctttt tctaataaag tttcacaact
    40381 tgcattttct attatttcaa ttctgtcttc ttctttattt ttactattta ttaatctata
    40441 tggatgttct tcacctattt cattgttgga tataactatt ttacagcctt taaaatgttt
    40501 gcttaaatta tacttttcac ctattgtata gattttcttt agagcttctt tgctcaaaac
    40561 cttcttatac tcatatccca gtaatttaaa atatgtccca ttagttgata taatatatat
    40621 atcatcccct aaaacacttg taaaatattt catagcatta taaggtcttc ccgtaactaa
    40681 ggctaccttg ataccctttt ccatgacttc ttttagtgct ttaatatttt cttctgatac
    40741 ttcaaatcct ttacccatca aagtaccatc catatcagta caaattaatt tatatcgcat
    40801 ttgtatcaca tcctagtaag atttttctaa tatttcaaca aggtcttctt tctttccaaa
    40861 aggtaaaaat cctaaaactg gacagcttgt tatttgttct aattgttcct ttgttacatt
    40921 aaactcagac atttttgtct taagtcccac tctctttaaa aaactttcta tttcatttcc
    40981 taaagtttta gctgcttcat catcttccac tttttctaat tcttggttta gcattctcgc
    41041 tactttggca aatttctcta tattatcctt atagaacttt tctgcaaatt ttgggaacac
    41101 tatagccaaa gcctcaccat gaggaatatg tgtaactcct cctattattt cacttagtgg
    41161 atgtggtgct gctgctccag catttgccag tgaacttcct cctaatgtat ctgctactgc
    41221 taactttgtt ctgtattcta tattattttt atcttccatt actttaggta gatagttaat
    41281 gactaattcc atagattttt cagacattat ctctgtaaaa tcattagcat ttggatttat
    41341 ataactttca aatgcatgag taaaagcatc aaatgctgtt gatgcagtaa ttctctctgg
    41401 cagagttaac ataagctctg ggtcaactat acattctttt gagaaacaat tttgatgaaa
    41461 tattgtattt ttctcgcttc ctctcgatat tactgctgct tgtgtaactt ggcttcctgt
    41521 tccagaagta gttgatacag ctattaatgg taattctttt tcacttacct tatcgtatat
    41581 tttaaatgga tttgtatatg tactaaacat ataatcccaa tctatctttt ctaaaccaaa
    41641 agtcaatgct aatacttttg cagtatctat acttgaacct cctccaacag ctaaaacaac
    41701 atctacagat tcttttttag ctaattcaaa cccttcattt attaattcta cagttgggtt
    41761 tggctctact ctatcaaagt gtacaacttc tatacctttt tctattaaat tcaatgtaac
    41821 tcttttatat aacttgtcta atggctctac atttggagta gtaactaaca aacatttctt
    41881 tccatatttt cctattattc taggtaattc acttaaagtt ccttgtccaa aatttattct
    41941 tgatggttga taaaagttaa tcatattttt cctcccttaa attattgcct tcatattcaa
    42001 attatacata tcataggatt tttaaggcaa taccttcact gttaactctt atttactaaa
    42061 gcttatggca attattagac aatcaatgtt ttattattac catatcatta tgtaaatttt
    42121 attaagtacc catgttataa ttttataatc aatcttattg tataattgac ttaataataa
    42181 aaatagagta tatacacttt tttatgacaa atagcttaaa ggagaattaa attatgaaat
    42241 atttgataga cagtgctaat cttgatgaaa ttcaaaagtg tttaaagtat ggatttaagg
    42301 gaataacagc taatccatct atgtatctta aagagaaagt aaacttccat gaatttattg
    42361 agacatgtgc taatttaaat ccagaaatat taactgctga agtcattgga aataatttat
    42421 acgaattaat taattcatgt gataagatat taaatataaa taaaaacact ataataaaaa
    42481 taaatttctc tgaagttggc ttagaactta taaacatatt aaatagtaaa ggtgtaaaaa
    42541 ctgcatgtac cttgattttc aatgtaaatc aagcatcatt agctataaat gcaggtgctg
    42601 attacctatt cccttttata ggtagaaatg atgaaaatgg gaatgatggt ataaaaaacc
    42661 ttacagaaat atgtaacctt atatcaataa atggatataa tactaaagtt gttgcagctt
    42721 ctattaaaaa tgtattccac ttaactcaag catctctttg tggatgtgat tatgcagctg
    42781 taacatatga tttatttaaa aaagcttctt ttaaccagct tacaatagat ggtgccaata
    42841 cttttgaaag agattggtcc aaggttaata aatagtaact aagatttagg agggtttgca
    42901 ttgaacaaaa gattattaga tattgctgaa ttattactca acagctcaga ctatattact
    42961 gtagatacta ttgccgaaga attaaaagtt agtaataaaa ctattcgtaa tgaccttgtt
    43021 attttagatg aatggctttt agagtttaat ttatccctag ataaaaaaac tggttcaggg
    43081 gttattattc taggtaatga agatataaaa cttaaagtta ttagagatat caatgataaa
    43141 tcaaattgta tatatgcata ctctcctgaa gatagaaaaa ggtatattct aagtaaatta
    43201 tttattaaaa attctaagtt taggattcgt gatatttgca atgaactaca tgttagtaga
    43261 gctactgtgc ataaagactt ggtagttatt caaaattttt tgcaaaactt taaagtgact
    43321 ctagttagaa aaaccaataa tggagtatat ttagagggaa aagagaaaga tattcgaaaa
    43381 gcaatttttg aacttgctac ggttaataaa agttatactg aacttaaaga aatattattc
    43441 tcgaaatcta atgaatgcaa agatacccct tcaacaaaaa tatttaagga gctatttaac
    43501 tatgattttg agaaattatc tcaaatcact ctacacacct tacaagtaga aaaaagtaac
    43561 cttagtgatg agtattatat aaacttctta atacatatag ctatatgtat taaaagaatt
    43621 tcaattaaaa gatatattaa cttatctgaa ggttttttta gagaattatt agaacatgaa
    43681 tactttgaaa aatcaaaaat tttatgtgct aacctaagtg aagcttttga cgtagaattt
    43741 attgatgaag aggtctgtta tatccttctt catatagaag gattacttaa atcaataaag
    43801 aaaactacta ctcttgaacc tcttaaaaat gaagaaatta cagagtataa tctatctgaa
    43861 gcaatagctg ttcattgggg aagtatacta aatttaaact taaaggatga tttaatatta
    43921 ataaagtctc ttgctaatca ccttaaatca gttctacaca gaataaacta tgggtttact
    43981 attacaaatc ccatattaaa tgatataaag agaacatttc cttatactta taaggctgct
    44041 aaagagtcta atactgttat caaacagttg atgaattatg aagtcaatga tgacgaaata
    44101 ggatatcttg ctttatattt aatatcagca atagatagaa gcaaatctcc ccttaatact
    44161 attttaatat gtcactgtag tgatggtgta tctaatttat tagtccaaaa gttaagtttt
    44221 gaatttaatc agattaatat agttaaatct atacctctat cttctatttc atttacgaac
    44281 tttgatgatg tggacttaat actaaccact gctcctgtag actttgaaca taatgctgaa
    44341 ctgataaata taaatgctct tttaagtaag aatgatattt ctagacttag tacaattata
    44401 aaaaaactat attctgaaaa aaataaaata ttatcttata aataaacaaa aataggcttg
    44461 tctcaacata gagataaacc tatttttcat tgtctaaatg ataaaaatat atttgatttc
    44521 atagaaaaag tgcctcatga actaaaaaat tcattttgag acacctccat tttttatatt
    44581 taagcttttt atttaagctt ttatattttt taaactttta tatttaaagt aaattttatt
    44641 atttttattg agcacaagca ttatttatat tattaatttc ttcagtattc ttaccaaact
    44701 ttgtagttac aaatcctatt gtttttatta tgagtaataa agatatcaat gaatatatag
    44761 atatcataaa attcttactt attattccag acgctactat tataaatcca tctagcataa
    44821 ataatataac tggcaacttc agaaacttaa ttaccttatt aataagcatt gcaactaaat
    44881 cagttccacc agtactacag ccccttatta ttgctatccc tatagcagtt cctaccaata
    44941 acccacctat cactcctgct actaatagat tgtcagttat gtgagtttgt ggtattactt
    45001 ttaagaataa tgggcccata agagttatat ataatgtttt tattccaaaa cctttcccta
    45061 aaaataataa tcccattact aaaagtggca tagatattcc taatgatata ttctcaacag
    45121 gcattgataa gaatgtgcta agtacgactg ataatcctgt tatccctcct ggagctaatg
    45181 tatgttctgc aaagaaaaaa ttaactgcta atgccattaa aaatgctgat attgttatca
    45241 gtaaataatc ttttatcatt tcttttttca tttaataacc tcctatgatt atattatttc
    45301 agtataaaaa atcaattaaa ttagtctagc ttcctgtagt ttttcataaa attaatgctt
    45361 ccttaaaaca ttaagaaagc atctctttta tcatagttta ttatcttatt ctaaaccaaa
    45421 ctttgtagct gctttatcta tagcttttct acaattctta acacctgctg ttataccatc
    45481 tttatccttg aatattgctg aagataatat tacaacgtct ggattacatt ctattaatgg
    45541 ctccatattg tctgctctta gtccaccatc tattgctaat tcacacttag gattcttttc
    45601 gtctatcatt tttctagctc tttttactaa atcaacagca ctctttctcc atccccagtt
    45661 atcttttcca tcagtttcat caacaccatg aacgactatt tgcaatctat ctatatcata
    45721 tatagcttca tcaacaaaac ataatggtgt gtaacatcca attgttaatc ctactttcat
    45781 accaaattct ctacagtaat ttattatgta tgcaagagga gcacctaaaa aatgttctgc
    45841 tggtattatc aacaagttac atcctgctgc tgctattttt tctataaata atctatcaca
    45901 atctcttgtg tatatatggc attctattgg tttatctgtc actggtctta ttgcttctat
    45961 tatttgatga ccacccataa gttgcatatt ttttaagtca tgcatatctg ctgcatctga
    46021 atgcacgtag tctacacctg catccattgc ttctttaact acggctgata tatgaccgta
    46081 atttacatgt gctaatcctg ctgctatttt tatgtgtttc atatttgtat acctccatat
    46141 tttactttaa ttagtattaa atattagttt ttgatatttt tttaatattt tttaatccag
    46201 tattactttt atttagcatt acttttattg ctgtatatat ttcttttatg aacttattct
    46261 gcttttgtta actgtgaact tattttgctt tgtaaattaa tattacactg atatattttt
    46321 tttcacaaca ctttgactac tccttaaaag tacctttata ttgtggtaaa ttatagacat
    46381 taattgtata taaaaagtta gttttttacc acattcttat ggcatttatt gtctatacta
    46441 actcaattga tatagctagt tcatttaata tataatcaga ctataaatat aaatttactc
    46501 gataaaaagt accattcata acaatattaa tgaaagggag atgtaaaatg agaaactgta
    46561 ttattgccca atctggaggc cctacagctg ttatcaatgc ttctgcagtt ggtatttatg
    46621 aaaaaaattt agaaactaaa tactttgata aagtatattt tggtatcaat gggattgaag
    46681 gtatattaaa caaaaatata atagattcag actccttaaa caaagataat gtattaaatt
    46741 taaagcaaac accttcgtct ggtcttggtt cttgtagata caaactggct gattataaaa
    46801 taaattctta tgattatgat agagttataa atatactaga tgaatatgaa atagatacat
    46861 tattttatat aggcggaaat gattctatgg acacagtgat gaaattttct caatactgca
    46921 aaaacactac ttgtaaaata aaatttatag gtattcctaa aacaatagat aatgatttat
    46981 taggaactga caactgtcct ggatttggtt ctgctgcaaa gcttatttct acactaataa
    47041 tggaaacata cttagatttt tctatataca aaaataatgg tatatttata gtagaaacta
    47101 tgggtagaga tactggatgg ttagcagctt cttcttcact agctagactt aatgatactc
    47161 cacttgttga tttaatatac cttccagaaa ttgatttcta tgaagataag tttatagaag
    47221 atgttagaaa aatatttaaa gaaaaaaata aggcttatat agttgcgtca gaaggtataa
    47281 gggataaata cggcaacttt atatgcgaac aaaaaacttc tgctcatgat aaatttggtc
    47341 attcccaatt aggtggagta agcaactatc taaagaatct tatagtatca tcatcaatta
    47401 caacaagagt aaaaacctta gaacttggtg taatacaaag atgtgctatg catttagctt
    47461 cagatactga tttaaaacaa gcagctgaag ttggtgcata tgggatagaa ctatctaaaa
    47521 aaggatatac aggagttatg gctatcatta atagaacatg caataatcct tataagtatg
    47581 aagttagtca tactgatatt tctaaaatag ctaacaagac aaaatatttt cctaaagagt
    47641 ggataaatga agaatgtaat tatataactg atgaagccct aaattatcta tatccactta
    47701 ttcaaggtaa accagatatc aaatataaaa atggactacc ttatttttca attatttact
    47761 aggaaattat tataatttga tatacactca attctatcgc tcttaaatac ctaagtggct
    47821 gttaaataaa attataaatt gttatatgac agtcacttaa tcgtttaatt atttaactgt
    47881 ttagtttttt aattttttaa tcttttttaa tactaatacg atttgttgta ataatatctc
    47941 acacccattt tcattttgga tagattataa ttagttagac aataaatatt ttgtcatgat
    48001 attattatat atagtgatac aaatagaaat acttttatca tggctagaaa aacaaagatt
    48061 acacaaagga tttaaaaatc aaacaacttc aattaaaata aatggttaaa ataacttcta
    48121 aatcaactac tataaacaat aaaagaacat aaagtagtta agtctacaat tataaaatta
    48181 gtaagactat aataacttaa ataaaattaa agttaacaaa gactattaaa gttagcaaat
    48241 attcctctac ctaaataatt gctttttata aagagttatt tattttaatt gaatttaatt
    48301 gaaatacgat tttaactaga acaatagatt aatgtaatat ttaatataaa ataattataa
    48361 taattgaaaa ggaagtaatc tatgatgaaa atagcagtca taacaaccga atttttaaaa
    48421 gagtttgtag ataattctat aaaaaagtta aatattaatg cagaaattga aatatatatc
    48481 tatagagatt tttctcatgt tggagattta tatttagaaa tagaagatag gtttgatgga
    48541 tttgcagtta gtggccccat ccccaaaaaa gctattacaa aaaaggctgg aactattaaa
    48601 aaacctctag ttgattttgg tactgactta caaagttact atgatatgtt tctaaagctt
    48661 atctttaaat ataatacatt agatttttct agagcgtact ttgacttaac agactgggca
    48721 gataatccaa aagatatatc atattattta tcaaatggca catttggaga cttaatggat
    48781 agtattgatg aaaatgcatc taaaatgagt ttatctgaca tagcaaaact tgaaaaaaag
    48841 attgcaaaaa aacatattaa tctatggaat gaagggaaaa tcgatttttc tactactcgt
    48901 tttagtagta ttgttcctat gttacaaaat gcaggagtaa actttcattt catataccct
    48961 gatatagatt tattaaaaaa tacttttaat aacttaataa aagatattca tttacataga
    49021 atgaagggaa atcaaccaag tgtaatatat ataacagtta aagatacaaa ttatgatgac
    49081 tctactctag accaagttta taaaatatta aatagtatta aaaaagataa attaaccgat
    49141 tttataattg aaaaaaatag taattctttt aaaattttca ctaaatgtga aacgattaaa
    49201 tcattaacta aaaattttac tgcatgttat ataaaagaat ctattgaaaa tagtacaaat
    49261 attaaagtat gtgttggata tggaattggt aatgatataa agcaagctat gtctagtgcc
    49321 ataagtgcta ataaggaatc taaaataaat catttaaatt acagtttctt agtcaacgaa
    49381 aattatgaga caataggacc tttactgtgt gataagttac ttactgtttc aaataaagta
    49441 actccacata taaatacaat tgccaaaagt tctaaattgt ctactcttac tattcaaaag
    49501 attatatctg ttactgaaat tctacaaaga gatgaagtta ctcctaagga attatcttca
    49561 tgtttaaatg taacagttag aactgctaat agatttctaa gtagtctctt aaagtctgga
    49621 aacgctacta tattatatga aaaacaaaac tcaacaaaag gtagacctga aagagtatac
    49681 aaattattta tatcagaaaa taaatattaa aatccaaaat gcataaaaat attttatcat
    49741 ctaatattaa gtaaaattat atatgacttt ctaaaaggta tatctttgca tctttttaag
    49801 atataccttt tataatattt aataatattt tatgttatta tctactaaaa ttattttcta
    49861 accattttac tgcacaatga gcaaataaag ctgaaccata aactaatccc tcttcattaa
    49921 aaattgcttt aggattatgc ataccaaaat tatatccctg actaatactt cccattccaa
    49981 tccataaaaa tactcctgga acccttagta aaatctctga aaaatcttct gaacccattg
    50041 cagatggaaa gtctattaca ttttcatttc ctataacttc tttaacataa gatacaatct
    50101 catctcctac atccaaatca tttataactg caggagtccc cattttaaat tccactttag
    50161 catttcctcc aaatgattta gctattcctg tagatatttc aataattcta ttttttaatt
    50221 tttctctaac agattggtca aatgttctta aagtacctga catagatgct ttatttggta
    50281 tagcatttgg tacgcttcct gcattaaaca taccaatagt taaaactaca ggctctttct
    50341 gaggtttttc tcttgaaagt atagtgttta atgctatttg tatatgtgac attatgttta
    50401 ttgggtccac tccaaattca gggcttgctc catgagttgc ttttccttct actgttattt
    50461 caaatatatc tgcagatgcc atagctggac cacgtgaata agctacttga cctgtgttaa
    50521 gaaatttacc caccatactg tgaaatgcca tagctgcatc gacctgagga ttttctaata
    50581 taccatcatc aatcattgat tttgcacctc tggtagtctc ttcatctggt tcaaatacaa
    50641 actttactct acctttaagt aagtgcttat tatccataag tattttagct gctcctaaga
    50701 gcattgctgt gtgattatcg tgtccacaac tatgagatgc atctttattc ttacttttaa
    50761 aaggtaaatc cgtctcctcc ataataggaa gtgcatccat atctgccctt aataataagg
    50821 tctttccacc atttttactg tctaaaacag ctactattcc attattagac gtcaatttcg
    50881 gagaatatcc cattttttct aaagtactgg taacaaaggt tactgttttc ggtagattgc
    50941 aaccaatttc gggattttca tgtaaatatc ttctccatct aataatttcc ccttctattg
    51001 actgcgcttc tttaaaaaaa tttttcatat tccttcctcc taatcagata gtcagcaaaa
    51061 tctcactttc ttttagtaat gaaatgatgc tgatataaaa attataattt tatatattaa
    51121 atttcatgtc tttttaagga gttggaatat catctggaat aggacattta tatgttttac
    51181 cattcataga tttatcaaat tcttcttttg cctttttagc tatctctgga ttatttaata
    51241 ttttagctcc aaacatagcc ataatctttg atgcatatat catacctttt tctcctatag
    51301 aacttcctgc acaagatgta aactgccagc tatgacctgg tgctcctaga ttcgtacacc
    51361 ctgtaaaaaa gtatgctgtc ggaactatat gcattacatc tccaatatca gtagagccat
    51421 aactattaaa gtttgtaaca tttcctccac cataatatag atgagttcct tctggcaaat
    51481 tatatttact tatcatagcc ttatattgtt gtgggctttg tctatctaat tcagctgcaa
    51541 aatccaattc ctctcgagtc caaggctctt gtttaatctc attcatacat tctgatacaa
    51601 gatttgctaa aacatgattg tttaaagtat tataacaccc tcctaaaaac tctacttcaa
    51661 cttcagtttc agtcatcatt gcagctcctt ttgctacctt tacaagtctt tcatatgtac
    51721 tttctacagc ttctctactt aaagctcttg tataatacca tactgatgct ttatcaggaa
    51781 ctatgttggg tgctactcct ccatctgtaa ttgtataatg aatccttaca tcagaagtaa
    51841 catgttctct caaataatta gctcccacat tagtaagttc cacagcatct agtgcacttc
    51901 ttccattttg agggtctgag cctgcatgtg cagtctttcc cttaaagtga aactttacag
    51961 agttaacagc tgttgaagta ccaattgtag cttcactaat tttatttgga tgaaaattta
    52021 tagctaagtc taacccttca aacgctccac ctctagccat aaatccttta cctgttaatt
    52081 gttcttctcc tggacatgca taaaatacta tagtcccact taagttattt tctatcatct
    52141 ctcttttaag ccctactact gcccctacat gtgctgtaca taataaatta tgcccacatc
    52201 catgaccata tgcacccaat tcaaatgctt cttgttttgt tgaaactttt tgatttaaac
    52261 caggtaatgc atcaaattct cccataaaac ctataactgg tttacctgaa ccaaaactag
    52321 ctctaatagc cgtggctaaa cctcctacac ctacttccac atcaaatcct tcacttctta
    52381 gaaagtttgc tgtattttca catgctttaa attctttaaa tgctttttct ggattttccc
    52441 atattttctt acttaaatca tcaagtttga atcttttttt atctatctca tttatagata
    52501 tacttcctat cattttctat tcctcctata aatctattta ctatcaacca aatataattg
    52561 gacctattat actagcaaat gccactgatg caatggttac agtaacaaat cctcctataa
    52621 tcatctttgg taataaataa tctgttgccc tttgtttttc ttcttcagtt ccttccatag
    52681 catcaatacc ttcattggaa attatctgtg ttgcaggata agctagcata caagttacac
    52741 caattgcagc tgacattctt ggagaatatc ccaatagttt tcctacaatt gcagtaaata
    52801 gtattataaa tacagagcct acaacaagta ttcctatagt tggaataatc atcccaaaca
    52861 atgctgttgg agttacctta gcaagtcctc caggtaacat caacatacaa ccaaacatta
    52921 taattccatt agattgagat ttatctaaaa ttcctttttc taaaaaacct attcgtgtaa
    52981 aaatcaaccc tactaacaaa catgctatgt tgggatttaa ataatagttt gcaggggtaa
    53041 atcctggtat taaagtagcc aatcctacaa aattaccaat catagcaaca aatgaaagct
    53101 ttgcaagata tactaaagta gatgattttt tacctaaatc ttctttaaaa attctcatac
    53161 ttggaagttt aaaattactt tttgactcat ctttcaaaaa atccccgtta tctcttttaa
    53221 attttaattc tttatttata caatatgtag ttatcggaat gccaaagaac ttttgaaatg
    53281 ataatactag aattacaaat gcagcaagtt caggtctatt tgcagcttct gcaacagttg
    53341 ttacgataat accagcaaca gtagaacccg ctattggagg tgctgctatt aaagcatact
    53401 ctctaccaaa taacatacta cccactgtta aacagccaac ccctattcct acaataccta
    53461 ctaatgcaat tacaaccgtt ttccattcat gacataagtc ttcaagattt ataagtgttc
    53521 ctaagttagt tattaataaa gctataccaa agttgctcat tgcagctaat atccctgatg
    53581 ctcctgtaat gtcttttggt aaaatatttg tccaaaatcc tagtaaaaat ataatacata
    53641 caaataacaa tgttgaaatt gcaccttttg ttttcttaga taaaaactca ctaaaagcat
    53701 aaatcattac acatacagta aagcaagtaa gtggattcca aaaattttcc attgttgttt
    53761 cctcctaaat ataataattt tttatcaata aaacaataat tataaaatgt atattatgca
    53821 gttattctta actacatatg gtatagcttg atattttttg atgatattat atacgtccta
    53881 aattattcct aaaatatcta aataaatata actagagtta actctctaaa tattaactat
    53941 agttatcaac ttactagatt tctttttgat ttttactttc tacataattt tacgagttag
    54001 aattgtactt caactattct ctatattagt atacatgttg gaagacttat atttatttaa
    54061 atattagata tagaatatat ttttataaac gtcttaaatt attcttaaaa tatctaaaac
    54121 gaaataataa tatacccatt aaaccaatat tatcagaata tacttcactt taagtcttct
    54181 ttatatagaa attttatcta ttagtgcatc ccctcccttg taaattagac tatttctaag
    54241 cgaatttaga tatcttattc ctagagacta ttactaaaaa caaaaattat ttattatatt
    54301 aaatcaatga taagccata
//
LOCUS       DAJMZY010000015        52905 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.015, whole genome shotgun sequence.
ACCESSION   DAJMZY010000015 DAJMZY010000000
VERSION     DAJMZY010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 52905)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52905)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52905
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.015"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            complement(<1..884)
                     /locus_tag="OE968_000850"
     CDS             complement(<1..884)
                     /locus_tag="OE968_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009243519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HCP7218163.1"
                     /translation="MKLKHIAIIGSLFPILFSLVLFFGVLISADSDDENSNFSSGITG
                     MNLSAEVLKHQTMVEKYARENGISEYVNVLLAIIQVESGGTAEDVMQSSESLGLPPSS
                     LDTESSIKQGCKYFASLLSSCKNQDIDDLNVAIQSYNYGGGYVGYVAGNGKKHTFNLA
                     ESFAREKSGGKKVTYTNPIAVAKNGGWRYGYGNMFYVELVNQYLTVPQVSGELAQKVM
                     NEALKYQGWKYVFGGSSPTTSFDCSGLTQWCYGKAGISLPRTAQAQYDATQHLPLSQA
                     KAGDLVFFHSTYNAGSYVT"
     gene            complement(881..3085)
                     /locus_tag="OE968_000851"
     CDS             complement(881..3085)
                     /locus_tag="OE968_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCP7218164.1"
                     /translation="MKERIQSAFTKRKILHFLKMALFVVALSLILLSLLGTVAHATGL
                     VDDTINAENLYSKYPLSNYQLDFFVDNSWSWLPWNWLDGIGKSVQYGLYCITNFVWTI
                     SLYLSNATGYVVQEAYKLDFINDMADSIGKSIQTLAGVTENGFSSTGFYVGFLLLIIL
                     VVGMYVAYTGLIKRETSKALHAVINFVVVFVLSASFIAYAPDYIKKINEFSSDISTAS
                     LDLGTKIMLPNSDSEGKDSVDLIRDSLFSIQVQQPWLLLQFGNSNAEEIGTDRVEALV
                     SASPEDEDGKTREEVVKTEIEDNDNNNLTIPQVVNRLGMVFFLLFFNLGITIFVFLLT
                     GMMLFSQILFIIFAMFLPISFLLSMIPSYESMAKQAIVRVFNTIMTRAGITLIVTVAF
                     SISSMFYNISTDYPFFMVAFLQIVCFAGIYMKLGDLMSMFSLNAGDSQSMGRRIFRRP
                     YLFMRHRARRMEHRIARAVSAGGISGGVAGAVAGSAVAGKRAERKNTASKENRGNTTS
                     SMGQRAGSKVGAVLDTKNKVKDKANAVKENIKDMPTQTAYAVYSAKEKAKSSVSDFKR
                     GMVQEQQSRQTGRLEKQEQHKKSIAVKRMELQKAQEARQAQRKADGSATTGATRPHER
                     PATASTVSKTGAEKMQEVKRPATTPTTKASEPVKTSGVKERPLSSSTPDGKATQSTYR
                     QNVEKVTVSKETRQNYTKDRRTKVQQTQTVQKNQQTTEKIRNLVTKKGQKKK"
     gene            complement(3085..5535)
                     /locus_tag="OE968_000852"
     CDS             complement(3085..5535)
                     /locus_tag="OE968_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HCP7218165.1"
                     /translation="MFPIKYIDNNLVWNKDNEVFAYYEMIPYNYSFLSAEQKFIVHDS
                     FRQLIAQSREGKIHALQIATESSIRSMQEQSKKLVTGKLREVAVQKIDEQTEALVSMI
                     GDNQVDYRFFLGFKLMVTEEQLNLKNIKKSAWLTFKEFLHEVNHTLMNDFVSMPNDEI
                     NRYMKMEKLLENKISRRFKVRRLEIHDFGYLMEHLYGRDGIAYEDYEYQLPKKKLKKE
                     TLIKYYDLIRPTRCVIEESQRYLRLEHEDKESYVSYFTVNVIVGELDFPSSEIFYFQQ
                     QQFTFPVDTSMNVEIVENRKALTTVRNKKKELKDLDNHAYQAGSETSSNVVDALDSVD
                     ELETDLDQSKESMYKLSYVIRVSAPDLDELKRRCDEVKDFYDDLNVKLVRPAGDMLGL
                     HSEFLPASKRYINDYVQYVKSDFLAGLGFGATQQLGENTGIYMGYSVDTGRNVYLQPS
                     LASQGVKGTVTNALASAFVGSLGGGKSFCNNLLVYYAVLFGGQALLLDPKSERGNWKE
                     TLPEIAHEINIVNLTSDKDNAGLLDPFVIMKNVKDAESLAIDILTFLTGISSRDGEKF
                     PVLRKAVRSVTQSENRGLLHVIEELRKEDTAISRNIADHIDSFTDYDFAHLLFSDGTV
                     ENAISLDNQLNIIQVADLVLPDKDTTFEEYTTIELLSVSMLIVISTFALDFIHSDRSI
                     FKIVDLDEAWAFLNVAQGETLSNKLVRAGRAMQAGVYFVTQSAYDVSKESLKNNIGLK
                     FAFRSTDINEIKQTLEFFGIDKDDENNQKRLRDLENGQCLLQDLYGRVGVVQIHPVFE
                     ELLHAFDTRPPVQRNEVE"
     gene            complement(5513..5911)
                     /locus_tag="OE968_000853"
     CDS             complement(5513..5911)
                     /locus_tag="OE968_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009274602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HCP7218166.1"
                     /translation="MKKIKSYTGIWNVEKVLYAINDFNLPFPVTFTQITWFVITEFII
                     ILFGDMPPLSMIEGAFLKYFGIPVALTWFMSQKTFDGKKPYSFLKSQITYALRPKITY
                     AGKAVKLHKQILNETITAVRSVNYVPDKIY"
     gene            complement(6029..6532)
                     /locus_tag="OE968_000854"
     CDS             complement(6029..6532)
                     /locus_tag="OE968_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004843360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HCP7218167.1"
                     /translation="MIDDMAVYIANLGRYNEGYLVGAWFTFPIDEEDVKEKIGLNEQY
                     EEYAVHDTDNFPIDIGEYVSIEELNEMYEMIEELPDYIVECLDEFISHYGTLEEVVEH
                     KDDIYFYPDCETMTDVAYYYIDELNALGDIPANLQNYIDYEAYGRDLDMGGRFIETSR
                     GICEIPY"
     gene            complement(6550..7053)
                     /locus_tag="OE968_000855"
     CDS             complement(6550..7053)
                     /locus_tag="OE968_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004843359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HCP7218168.1"
                     /translation="MQETRVLVETGRTNGEETTSYWFDLPIDVAEFEEKLGVGAESQD
                     YRIIEKVLPYADEVHEHTSVYQLNELDFMYRQLSADMQEEYVELLTVFENLEALYICR
                     NVITVYHDCKSMIDVARQKLMNDPTFKHLSEDCQAYYFDFEAYASHLLENKRYLVTEN
                     SIFELPE"
     gene            complement(6972..7268)
                     /locus_tag="OE968_000856"
     CDS             complement(6972..7268)
                     /locus_tag="OE968_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005339688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HCP7218169.1"
                     /translation="MNDIFKDMQAKVGCEYISDLPSYKRKVWHEMKRLNPADYEEKQL
                     KDFSKYVFGMSYQTLKDVMKQQKGREEQCRKQGYWWKREEQMAKKQHHTGLTYR"
     gene            complement(7367..8161)
                     /locus_tag="OE968_000857"
     CDS             complement(7367..8161)
                     /locus_tag="OE968_000857"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218170.1"
                     /translation="MGTINYFLKGIKVLMISDEMRVDILHAVFINKNFIKDEENCNYE
                     KYLLELVNKSIYFREKSNFAEYVPPKSENHGECDCNSPNYQMDFKLLESTTRLHASKE
                     LTGQIQKFCDGVIGKCPPRRPNTQMTVTRLFASLRDYDCESLHSCLTEKYEYGTIEFD
                     IQTYVKLLTFKKNLFFFFPYKFSFNTCYNFKYALDSIRIALEKDFRESNLFREKYYAE
                     YDTFLAYIYEDNLIISKFEQDGKLQMIDCIYLFKSQTYSKLYEYTW"
     gene            complement(8200..8421)
                     /locus_tag="OE968_000858"
     CDS             complement(8200..8421)
                     /locus_tag="OE968_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002570387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218171.1"
                     /translation="MNFGQNLYQWFLSNAQSLVLMAIVVIGIYLGFKREFSKLIGFLV
                     VALIAVGLVFNAGGVKDVLLELFNKIIGA"
     gene            complement(8422..8556)
                     /locus_tag="OE968_000859"
     CDS             complement(8422..8556)
                     /locus_tag="OE968_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017143882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HCP7218172.1"
                     /translation="MWELVKDFLLVSMGMGIGVVLMCILSISKEADYEMKQLEESEDN
                     "
     gene            complement(8569..9765)
                     /locus_tag="OE968_000860"
     CDS             complement(8569..9765)
                     /locus_tag="OE968_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HCP7218173.1"
                     /translation="MVLNEEQWIKELREKRIAYGISQGRLAVASGITREYLNKIESGK
                     MKPSKELLETLHKELARFNPEAPLTMLFDYVKIRFPTLDIQHIIKDILKLNINYMLHE
                     DYGHYSYTEHYSLGDIFIYTSADEEKGVLLELKGRGCRQFESYLLAQQRSWYDFLMDA
                     LIDGGIMKRIDLAINDHTGILDIPELAEKCRKREYIGKSRSYKYYQSGELIKHREDDR
                     EYMGSTLYLGSLKSDVYFCIYEKDYEQYVKLGTPLEEADIINRFEIRLRNERAYYAVR
                     DLLTYYDAEQTAFSIINQYVRFIDEEPDKRKNDWKLNDRWAWFIGDNRQSLKLTTKPE
                     PYTLDRTLRWVQRQVAPTLKMLKKIDKGNGTDYMETIEKQAILSEKHEMIIKQQTTPA
                     KDLVES"
     gene            complement(9950..11344)
                     /locus_tag="OE968_000861"
     CDS             complement(9950..11344)
                     /locus_tag="OE968_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008787614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HCP7218174.1"
                     /translation="MRMILNKGHRIRASDKNLVYRFSMGTLLFVFVAVILLLNTKQLM
                     RTDWEHFSLLDNGFTLSLYNFITILIATGVCALVAFLYYRFCYDSFKKLLHRQKLARM
                     ILENKWYEADTVQDSVFFTDLQSRSREKIVWFPKIYYQMEKGLLHIRCEITLGKYQDQ
                     LLRLEDKLESGLYCELTDKTLHDGYIEYTLLYDMIANRITIDEVRAENGCLRLMKNLV
                     WEYDALPHALIAGGTGGGKTYFLLTLIEALLHTNAVLYILDPKNADLADLGTVMGNVY
                     HTKEEMIDCVNAFYEGMVQRSEQMKRHPNYKTGENYAYLGLPPCFLIFDEYVAFFEML
                     GTKESVGLLSQLKKIVMLGRQAGYFLIVACQRPDAKYFSDGIRDNFNLRVGLGRISEL
                     GYGMLFGSDVKKQFFQKRIKGRGYCDVGTSVISEFYTPLVPKGHDFLQTIGFLAQARQ
                     DGTATCEAKGDGSD"
     gene            complement(11438..11875)
                     /locus_tag="OE968_000862"
     CDS             complement(11438..11875)
                     /locus_tag="OE968_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004056026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218175.1"
                     /translation="MCEECYSDENRITPLLNPLDCLENHTQYICGTCGRCICIEHDPN
                     RGLQRWNFPFKSLEIAKLYLRTADYTTKSSCGIYEIENSKGRVSYKIFAGNEDLHLFL
                     KKNKDKKCKQMTPVFNVGEYKEYPHTEVRKLTSDEIKQYMSER"
     gene            complement(11977..12360)
                     /locus_tag="OE968_000863"
     CDS             complement(11977..12360)
                     /locus_tag="OE968_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009588269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HCP7218176.1"
                     /translation="MRLSNGFVIDKEKTFGELKFTAVRDVFLQNEDGTPSTQLKKRIY
                     DLKCSLHGGIIPVSVPPEVPLREFPYNAVVELVNPVADTVSRKTYTGADVDWYVKAED
                     IVLKNKGNQNTGTSQNHTPQGQPKK"
     gene            complement(12376..12702)
                     /locus_tag="OE968_000864"
     CDS             complement(12376..12702)
                     /locus_tag="OE968_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HCP7218177.1"
                     /translation="MEMKYVVPDMAQSFGTLEFAGESEPIFERDKNNRKVIARRSYNL
                     YSDVQKGENVVVEIPVQAGEKHFKYEQKVKLVNPKLYGRGYAIGDVGHTDYVLVADDI
                     VAVEEK"
     gene            complement(12828..15872)
                     /locus_tag="OE968_000865"
     CDS             complement(12828..15872)
                     /locus_tag="OE968_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SrtB-anchored collagen-binding adhesin"
                     /protein_id="HCP7218178.1"
                     /translation="MKKILKRLCTGVLAFATVVTALPSTAVHAESKQYWTESEERVGI
                     VEKVMNDGSIGSTFNEGHLTVEGEDAYCIDINTDFKNGYKTRADASTRMSADQISDVA
                     LSLEYVKQYGEAHKELNYKQVYLLEQCVVWQRLSVHLGWQCDNVRASYDEIPKATQDE
                     VFAGAKAFVKENKGRYECGGYIYSGEGQELGQFWAKLNVGNAKLQKTSSNTSITDGNG
                     NYSIAGATYGVFSDKDCTKQLATLTTDKNGNTDVVEVKAGTVYIRELSAPAGYKVDTT
                     VYSLKVEAGKTATLNVSDTPKVTDTLIELFKIDMETQKDNPQGNASLEGAEFTWKYYA
                     GFYNKDNLPAEATRTWVTKTIAETDSDGTTHYITKLADAYKVSGDSFYMQDGKAILPL
                     GTLSVEETKAPNGYLLDGAYMQAGDKSEQIKGLYLTQITEDGDLAVLTGSNQFSVSDK
                     VIRGGVKIQKRDLETSDTKPQGSATLKDTAFDVISLNDNSVLVEGKLYKKNEVVKTIR
                     TDIEGVASTSADLLPYGKFRIVESEAPDGYLTDGAKPIDFAITENGKIVDLTDEAHSI
                     YNQIKRGDIEGVKIGAGTHKRLADVPFRITSKTTGESHVVVTDDNGQFSTSAEWTSHK
                     HNTNAGKTSEDGVWFGTSEADDSKGALPYDTYIIEEMRCDSNKGFELIPPFEIVVSRN
                     NLVIDLGTLTDEYEKEISIHTTATSKDSEKTILAGKEVTIVDTVKLDGLTKGTKYQLK
                     GWQMLKEENAELIIDGKRVENDYTFIADDEEMKVEISYTFNASELGGKNLVTFEELYD
                     LSNPDEPVKVAEHKDIEDDGQTVLITERIIKIHTTATDKDGNKEIEAGKDVTIIDTVT
                     LEGLEVGTQYKLVGWQMLKEENAELLINGKRVESDYTFTADSETMKAEVAFTFDATSL
                     DGKQLVTFEELYDLSNPDEPKKVTEHKDIEDEGQTITFNEKPEVPEKLETPQTPEKPN
                     RPSDSPKTGDSTNVMAFLVMLLTSAGGLAGTYLYKRRTMKKS"
     gene            complement(16115..17479)
                     /gene="rlmD"
                     /locus_tag="OE968_000866"
     CDS             complement(16115..17479)
                     /gene="rlmD"
                     /locus_tag="OE968_000866"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HCP7218179.1"
                     /translation="MLSKNEMYIVDIVDIGQGGVGVGKYNGITVFVEGGLIHDKVKVR
                     INKVKKNYAVGDIVEIIEKSPFRVKRVCSDNLRDCGGCQIQDLDYNKQLEMKTNEVKQ
                     VLSRIGKLEDVEVHDTIGMDNPYRYRNKAQFPIQKNNGIPIIGFYKKKTHDVISTEKC
                     VIQHEINDKIVKIIKTYIRAYKVSIYDEKTHTGLIRHLVTKIGFTTKEVMVVLVANGN
                     KLPYLKELASVLKENIPGFKTLVVNVNQKDTNAILGRENIVIYGDGKINDYIGDLVFE
                     ISPLSFFQVNPVQTKVLYDKALEYANLNDTDTVFDIYCGIGTISLFLAQKAKKVYGIE
                     IIDDAIKDAKINAKLNNIHNAEFYVGKAEEIVPKMYREGKTANVVVVDPPRKGCDEKV
                     LETIVSMNPERIVYVSCNPSTLARDLDYLNVHGFKCVEAQPVDMFPHSTHIETCVLLQ
                     RRTM"
     gene            complement(17654..19414)
                     /gene="pyk"
                     /locus_tag="OE968_000867"
     CDS             complement(17654..19414)
                     /gene="pyk"
                     /locus_tag="OE968_000867"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HCP7218180.1"
                     /translation="MLNNVKKTKIVCTLGPASQSEEVLTQLMQNGLNVCRFNFSHGSH
                     EEHKERIDMAKKVREKLNKPVAILLDTKGPEIRTGNFEDPEVFLEEGQKFTITMKDIM
                     GTKEMCTVSYKGLAEDVKSGDSILIDDGLVGLRVKEINGEDIVCVVENSGIVKNHKGV
                     NVPGVKINLPAITPKDISDIEFGISQGIDYIAASFVRKASDVLAIREVLENNNATDIQ
                     IISKIENQEGVENLDEILKVSDGIMVARGDLGVEIPTEEMPIVQKMMIKKCNELAKPV
                     VTATQMLDSMIRNPRPTRAEVTDVANAIYDGTDAIMLSGETAAGKYPVEAVKMMATIA
                     KRTEETLDYDRLLKENGTNNVTVTDAISHATCTTAVDLNASAIITSTSSGYTARMVSK
                     FRPKSPIIATTNNEKTMNKLALTWGVYPVKSSVAGNTDEVIEKAIEAARQADYIDNGE
                     LVVITAGVPVGVSGTTNLIKVHVISEEIVQGIGVGTQTVEGKVRIIKNGNACVDFNEG
                     DILVSTATDAEMNNYIEKAGAVVTENGGMTSHTAIVGINLDIPVIVSAADITNLVKDG
                     EVVTVDASRGVVYRGSTRVL"
     gene            complement(19466..20425)
                     /gene="pfkA"
                     /locus_tag="OE968_000868"
     CDS             complement(19466..20425)
                     /gene="pfkA"
                     /locus_tag="OE968_000868"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HCP7218181.1"
                     /translation="MKTIGLLTSGGDAPGMNAAIRAVVRSAIYYGCKVYGINRGYKGL
                     LEEDLTEMNLSSVGDIIHRGGTILKSSRCEEFKTEEGRLKAVKILKKYKIDCLVVIGG
                     DGSFAGAQKLSDLGFPAIGIPGTIDNDLAYTDYTIGFDTAMNTIIDAIGKIRDTSSSH
                     ERVNIVEVMGRHCGDLALYAGLAGGAETIIVPEVEITVDEVALRLKTTQKRGKRHSII
                     VLAEGVGSASDLEKELKKESGADLRVTVLGHVQRGGSPTVSDRILASRLGVRAVELLL
                     DGKSARVVGIKENKIIDLEISEALAQKKVFDKEAYEMAKILSI"
     gene            complement(20634..24203)
                     /locus_tag="OE968_000869"
     CDS             complement(20634..24203)
                     /locus_tag="OE968_000869"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HCP7218182.1"
                     /translation="MNKDFAHLHVHTEYSLLDGFSRVKKLIKRAKELNMSSIAITDHG
                     CMFGVIDFYKTAIKEGIKPIIGCEVYTAARGLRDKDPNYDKYQGHLVLLAKNMEGYKN
                     LIKIVSTSYVEGFYYKPRVDMEELKKHNKGIIALSACLAGDVARALMNRNYEKAKQFA
                     LDYRDIFGEENFFLEIQDHNLPEQKEVNSGLVKLSKETGIPLVATNDVHYVNKEDSKI
                     HDVLMCIQMGKTLNDPNRMRFGSDEFYLKSREEMEELFPYALEAIDNTVKIADMCNVE
                     FDFNTIHLPKYDVPEGYTPETYLRELCFNGLKERYDNPSNEILERLNYELDVIEKMGY
                     VEYFLIVWDFINFSKENNIIVGPGRGSAAGSIVAYTLKITDIDPIKYSLLFERFLNPE
                     RISMPDIDIDFCYERREEVIDYVKRKYGDDHVAQIITFGTMGAKAAIRDVGRVLDIGY
                     NKVDKVAKEIPFALGMTIDKALDTNPNLKELYDQDPETKEIINISKQIEGMLRHASTH
                     AAGVVISKNPVDEYVPLYKHQDAITTQFTMTTLEELGLLKMDFLGLRTLTVIRDTLDL
                     IEKNRVIKNYTEKIDFSKMDYDDPKVYEMLSSGNTLGVFQLESAGMRSFMKQLKPDNF
                     EDIVAGISLFRPGPMDSIPAYIKNKSNPKDVTYLHEKLKPIMEVTYGCLVYQEQVMQV
                     VRDLGGYSYGRSDLVRRAMSKKKMDVMEEERQYFIHGKFDEDGNIEIAGCIRNGVEEE
                     IANKIFDDMIDFARYAFNKSHAAAYGVLAYETAYLKTYYPVEFMAALITSVMGNTDKV
                     VEYIRECKALEIDVLPPDINKSFSKFSVEGDNIRFGLAAVKNVGVNIINNIIAERESN
                     GLFVDLVDLVKRLDQKDTNKRVIESLIKCGAFDNISENRASLMAGYESLLESVSMDRK
                     KNVQGQISLFDAFGDSEEDSDFQQIYSLPKRQEYEERERLNLEKEVLGMYVSGHPLSQ
                     FEKELQEKTSMDNGKLNSLKEEEESYLQMNETDVIMGGMIVTKTIKTTKRNEIMAFIE
                     LEDLYGAIEIIVFPQLLQKYNVILNEDNIIYVKGTLSIKEGENAKLIAREIKDINDDT
                     DFADRNYNSGRTRNVENIKPESGKKLYLKIDSMSDTDTTNNIVEIAKQYPGNDSIYLY
                     PMDENINGKRKAYKMTGALTCICDEFINNLEELLPKDNIKVKA"
     gene            complement(24360..25307)
                     /gene="whiA"
                     /locus_tag="OE968_000870"
     CDS             complement(24360..25307)
                     /gene="whiA"
                     /locus_tag="OE968_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HCP7218183.1"
                     /translation="MSFSTETKNELARVISGNECCNIAELSALVKSGGSIQIVGYKKL
                     NLKITTELNSIARKVFKLLKKNFNINTTISVNKNQMLKRNNSYVLMVTSEMGSEMLLK
                     KLGILEDKEGFFTINKISENLIKHEGCKRAFIRGAFLGGGSISDPEKNYHMEFVTNNE
                     EFADSLKELINSLGFNSKIVARKNNHVVYIKESEQISDLLSIIGGHHALLSLQNTKIV
                     KEMRNNVNRIVNCETANLSKTVNAAVRQVENIKLIQETIGISSLPENLQEIAKIRIEY
                     EDMTLKELGEMLEPPIGKSGVNHRLRKIEEIATDLKKKS"
     gene            complement(25324..25749)
                     /locus_tag="OE968_000871"
     CDS             complement(25324..25749)
                     /locus_tag="OE968_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HCP7218184.1"
                     /translation="MREEVSAGGVVLFGNTILLLRKFNGDWVLPKGKVEEGENNQEAA
                     LREVSEETGVKADILKYLGEIHYTFKENWDENRAVHKTVFWYLMQAKNMDTIPQKEEG
                     FIDAKFIHLDRVVDLARYDDEKEIIKVALQEIKKRLKKN"
     gene            complement(25818..26924)
                     /locus_tag="OE968_000872"
     CDS             complement(25818..26924)
                     /locus_tag="OE968_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HCP7218185.1"
                     /translation="MAKLLIIVGILGWIALIVSLFIYKKAKNEKVKLFQRSIVENREP
                     NVVVIGGGTGQSVFLRGLKHTTQNITAIVTVADDGGGSGVLREDLGMLPPGDIRNCLL
                     ALANIEPTMNEVMQYRFTEGLLKGQSFGNLFLAAMNGLYGNFEKAVYKLSEIFAITGR
                     VLPVTLEDVNLVAKLENGNIINGESSIPEESKIQKSSIDKIFLNPKDVKPLKDVIASI
                     YDADIIIMGPGSLYTSIIPNLLVEGIVDAIKSSVAPKVYIANIMTQPGETEGYNVLEH
                     VNAIVKHTDENLIDYVIANNEILPEEMLDLYKQDGAEQVLLDKKQKDKLKEMGIKTVE
                     KNLIEIKNNYIRHDAKYISNIVIELALNHNYNKS"
     gene            complement(26936..27793)
                     /gene="rapZ"
                     /locus_tag="OE968_000873"
     CDS             complement(26936..27793)
                     /gene="rapZ"
                     /locus_tag="OE968_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HCP7218186.1"
                     /translation="MKFVIVTGLSGSGKSETMRALEDMGFYCVDNLPPALITKFAELC
                     YQPNSSIDKVALGIDIRGRKFFEALHESLNYLEKENYEYEMVYLDCNDDVLLKRYKMT
                     RRNHPLAKDMQIPEGIKMERKIMEPLKELSTCIIDTTNMKPKDLKEEIKKIYSSGEDN
                     PNLTISVVSFGFKHGILADADLVFDVRFLPNPYYVEELRAKTGDDKEVRDYVMNSKIS
                     EEFYVKLLDMIHFLVPQYIEEGKQHLVIGVGCTGGRHRSVTITNLIAEDLSNKGYRVV
                     KKHRDSMLR"
     gene            complement(27824..28537)
                     /locus_tag="OE968_000874"
     CDS             complement(27824..28537)
                     /locus_tag="OE968_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HCP7218187.1"
                     /translation="MKILADYHTHTLYSHGKGTIEDNVKVAISKGIKTIGISDHSYKH
                     IAYGVKKKDILKMREEVDYLNDKYTDINILLGMECNILDDKGNIDMDDKFIRDFDYIM
                     AGYHFGSTPTSLRSLLNHCNNYIFKTEKAKEYNTKAVINAISNNDIFIITHPGDKGDV
                     YIEEVAKTAKKTNTRLEINSSHSFLNVNQLNKIKGLENKFIIGSDAHCPERVGDFELA
                     MKTISDSNLDISLVENIII"
     gene            complement(28541..29455)
                     /gene="murB"
                     /locus_tag="OE968_000875"
     CDS             complement(28541..29455)
                     /gene="murB"
                     /locus_tag="OE968_000875"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HCP7218188.1"
                     /translation="MNNQDIYINLLNILSKEDIKVDEPMKKHISFRVGGPADILVRPR
                     TEEQLKNVLKLVKEESIPYLIIGNGSNILIKDGGIRGVVIELADNFNSYEINDTRMTA
                     QSGALLSVLGKALQKQELKGFEFASGIPGTLGGALAMNAGAYGGEMKDIVKSVRLMDM
                     EGNIFELSNEQMEFGYRKSIISKNGYIALSAELELQEGNYDEIKSLMDDLATRRITKQ
                     PLNFASAGSTFKRPTGYFAGKLIEETGLRGLTLRGAQVSEKHCGFVVNQGEASAKDIL
                     DLIYVIKSAVYAKFGVMLEEEVKILGED"
     gene            complement(29728..30498)
                     /locus_tag="OE968_000876"
     CDS             complement(29728..30498)
                     /locus_tag="OE968_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HCP7218189.1"
                     /translation="MSKGFLTPGETAQATISAGIKKANISTQNAILLGLFGGAFIGFG
                     ALGSMIVSQTFGKIDPGVASFLSAMVFPVGLMLVVVAGAELFTGNTLMAIALMDKKIT
                     LGKMLRNWGLVYFANLVGSILLVALVFYSSTLTGDAATKAIAVAEAKVNSTIASMFLK
                     AILCNILVVLAVWMATASQDIMSKLASCWTVIMLFVLCGFQHSVANMFFIPMGMALGA
                     NITMVQFITNLVFVTLGNIVGGSIVVGGIYYLCYVKNS"
     gene            30816..32297
                     /gene="cls"
                     /locus_tag="OE968_000877"
     CDS             30816..32297
                     /gene="cls"
                     /locus_tag="OE968_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HCP7218190.1"
                     /translation="MFDISFFEMSIYEIAVTTIYIINFMVILNLIFREKRNINTTLTW
                     LLILVLIPALGFILYIAFGRNISKNNMFRLKEKDDKIIKSNILDTQVKLQSTSEIDSD
                     IHQHKDMIYALANSNNAHYTNNNDVWIYAESSQFFNSLLEELKKAKKYINIQFYIFKD
                     DKIGTEIIDILIDKAKEGVEVRLLFDAVGGRTLKNSTLSRLKESGVKVGSFFPSFLKI
                     VNFNLNYRNHRKIVVIDGKVGFVGGYNVGDEYLGRNPKFGLWRDTHTKLTGDCVIDLN
                     MRFILDWRYTTKEDLDLEKYFIEEDTNSNHPSENIGIQIVSSGPDISELDEIKYGYLK
                     MIQKARKYIYIQSPYLILDSTFIDTLKIACLSGVDVRVMIPSKPDHPFVYWASYSYAG
                     ELLKFGAKIYTYGQNAFLHAKTIVIDDSICSIGTANMDIRSFELNFEVNAFMYSSKKA
                     LEQRIIFENDILNSKEITLDIYNSRSTYIKIKESISRLLSAVL"
     gene            32615..33112
                     /locus_tag="OE968_000878"
     CDS             32615..33112
                     /locus_tag="OE968_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase subunit E"
                     /protein_id="HCP7218191.1"
                     /translation="MCDFISHNKQLFDELDIFIDSLATKEGALIQVLHEAQGIFGYLP
                     KEVQLHVARKLGVAPAKVYGVVTFYSYFTTEPVGKYKISVCLGTVCFVKGADKILSAF
                     EKQLGIKVGETTSDFKFSLEGLRCLGACGLAPVVTVNGKVYGKVKPDQVSEILDTYRE
                     LELNC"
     gene            33129..35015
                     /locus_tag="OE968_000879"
     CDS             33129..35015
                     /locus_tag="OE968_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoF"
                     /protein_id="HCP7218192.1"
                     /translation="MRKVNSFDELKVLADELKPNLSLRKNYSKENVLRRELLVCCDTG
                     CTSSNSLEIVSELENEIKKSGIQDKVSVRLTGCFGFCAQGPIVKVYPDNVFYVKVEPS
                     DAEKIVQSHLIRNTVVEELLYEEESLSKKVEEQEEMSFYKKQLRIALKNCGLIDPDSI
                     EEYIANDGYLALGKCLTSLTPQEVIAEVKTSGLRGRGGAGFPTGSKWEAASKNPAGPT
                     DKKFVVCNADEGDPGAFMDRSVLEGDPHSVLEAMAICGYAIGSDTGYIYIRAEYPKSI
                     ERLKVAIAQAEKYGLLGENILGTGFNFKLELKYGAGAFVCGEGTALMHSIEGRRGEPR
                     MKTYSSSKSGLWKSPTCLNNVETFANIPAIILKGGDWFANLGTEDSSGTKVFALGGKV
                     ENVGLVEVPMGTTLRDIVFEIGGGIPEGKKFKAVQTGGPSGGCIPTEHLDTPIDFGSL
                     SSIGSMMGSGGMLVLDESDCMVDIAKFFLEFTVEESCGKCTPCRIGTTRLLEILTKIT
                     EGNGTLQDLDDLENLAETIQTASLCGLGKAAPNPVLSTLQYFKDEYIAHVVDKKCPAG
                     KCQNLLSYFITDDCKGCTKCSRVCPAGCITGSVKEQHTIDTSKCLKCGACIDNCTFNA
                     IIKK"
     gene            35038..36819
                     /locus_tag="OE968_000880"
     CDS             35038..36819
                     /locus_tag="OE968_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron hydrogenase small subunit"
                     /protein_id="HCP7218193.1"
                     /translation="MSLVNLTINGKHVSAPSGTSILDAAKLINIKIHNLCHLHMNEID
                     KLDTCASCRVCMVETERGLVPACGTVIKEGMKVQTNSAKALNARRTIVELLLSDHPQD
                     CFVCEKNGDCELQTIAADLGVRKIRYQGSKSFAGKDTSTKSLVKDHSKCILCRRCETV
                     CNDIQTVGALSGVNRGFNTLVSTFFNSDMVETECTFCGQCISVCPTGALTEVDNVPKL
                     WDVLNKKEKTIVVQVAPAVRVAIGEEFGLEPGSISTGKMVAALKALGFEHVFDTNFGA
                     DFTIMEEATEFIERIQKGENLPILTSCCPAWVNFLEHNYPDKLNLASSCKSPQGMFGS
                     IAKNYYAPKILGINPEELYVVSVMPCVAKKYEASREELSESGILDVDLSITTRELAKM
                     IKEAAIDLPNLQDQDFDNPLGKSTGAASIFGASGGVLEAALRTSYEKITNKTLDNVNF
                     TNVRGLKGIREASIDVDGTTVNVCIVNTLKNARKIMDKVRSGECKYHIIEVMACPGGC
                     VGGAGQPYHHGNTEIVDRRANALYEIDRNKAIRKSHENPDLQAIYKDFFGEPNSDVAH
                     KYLHTHYFDKSCVYGECPQECACEEAK"
     gene            complement(36959..38755)
                     /locus_tag="OE968_000881"
     CDS             complement(36959..38755)
                     /locus_tag="OE968_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate oxidoreductase"
                     /protein_id="HCP7218194.1"
                     /translation="MGIEYFSKLLESSTEKELLLSKKSNNISTARLISFLIVIAGFAI
                     GFYNKNIVGIFVGVLSIIIFIALLVIHSKVKEEETYFKSKSEVLNKYIKRFGDGWKEF
                     KIDGKEYLKDENSQAKDLDLFGRASLYQYICVANTSYGKNFLAKYLWNENPDENVILE
                     RQRAIKELLSKDDFSIHIQTLSNIIGKEQKNNSDSSIESFIEYGENKNVYIPKWMHIF
                     TWGLPTATILSFIFCMLGFLPVLPVFLLFIIQLGFSGFGYPRLMQTLAPLFSFSRSIQ
                     VYEKMFEVLEKETFESAYLKELQDKLSKGSGVSRGVKQLNSIGNAVNLRYNQILYIIA
                     CGVLMWNYHCAEALERWKGIYGNQIRDWFESIGEFEALISLTVVSHVKENTCFPVIKY
                     EDTPRLKVEEVYHPLIAEKSVIANSIQLNSQTCIITGSNMSGKTTFLRSIGVNLVLAY
                     AGAPVCAKSFDATCMAIFTSMRIQDDVSQGISTFYAEILRIKSMIQYSLKELPMLVLV
                     DEIFKGTNSADRIIGASEAVKKLSKPWVISMVTTHDFELCDLSGSGDVEVVNYHFSEY
                     YVDDKIHFDYKIKDGRCKTTNAKQLMRMAGIL"
     gene            complement(38969..39898)
                     /locus_tag="OE968_000882"
     CDS             complement(38969..39898)
                     /locus_tag="OE968_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HCP7218195.1"
                     /translation="METSNKVSIREIIKELKLKVVYMPDDVDYYVYSQDINRPGLQFA
                     GYFDYFAYERIQIVGKTEYNFFGLMDSHIREEVLDRFFSYEIPALIISRDLEIKPDVI
                     EKAKKYKRILLSTNRNTTRLINRLSNYLDNKLAPHTTIHGVLVDIYGIGVLIKGESSI
                     GKSETALELIQRGNRLVADDAVEIRKLDESMLVGQSPELIRHFLEIRGIGIIDVRSLY
                     GVGAIKNSKMIDLVVHLEAWDETKYYDRLGLDKEYEEILGVNVEKLVVPVKPGRNTAM
                     ILEVAAMNFRQRGMGYDAAQEFTKKLSKLIDTK"
     gene            complement(39898..41715)
                     /gene="uvrC"
                     /locus_tag="OE968_000883"
     CDS             complement(39898..41715)
                     /gene="uvrC"
                     /locus_tag="OE968_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HCP7218196.1"
                     /translation="MFDIQEHLKKLPSEPGVYLMKDKYDHIIYVGKAISLKNRVRQYF
                     QSSKNHTSKVKSMVKNIYKFEYIITDSELEALILECNLIKRYRPKYNVVLRDDKTYPY
                     IKVTTNEDYPRILKVRRVLKDKAKYFGPYTNITAVNDTLELISSTYPIRSCKIDIDKA
                     IKNKTRPCLNLHINKCLGPCTGNVSKEEYGKMIEEIIMCLSGKEEKLMELLKEKMNES
                     SMNFRFEEAAVYRDKIKSLEEMIQKQKIDATVSDLNQDVVAMARAHNEACVQVFFIRN
                     GKIVGREHFILEGVMDSPRASILSSFVKQFYNEQEYIPKELIIEDEIEDSSILEEWLS
                     SKKGQKVTIRVPQKGEKKSLVEMVRKNAVEYLEKFSDMNKRKYEKSIGALEELKQILN
                     LEKLPIRIEAYDISNIQGVDSIGSMVVYTNAKKDKKEYRRYKIKTVIGPNDYDSMAEI
                     VDRRLKHGNLPDLILLDGGKGQVSAVKKVLELNDVDIPLWGMYKDDKHRTKGLICKEK
                     EIELDKTTNLYRFIASIQEEVHNYAITYHRSLRNKALTKSILDDIQGIGEKRKKSLLN
                     HFKDVDAIKKATMEELLEVDGMNKSIADNVYNFFRKEEN"
     gene            complement(41974..44799)
                     /gene="uvrA"
                     /locus_tag="OE968_000884"
     CDS             complement(41974..44799)
                     /gene="uvrA"
                     /locus_tag="OE968_000884"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HCP7218197.1"
                     /translation="MEDKIIIRGAKEHNLKNIDLELPRDKFIVFTGLSGSGKSSLAFD
                     TIYAEGQRRYVESLSAYARQFLGQMEKPNVEYIEGLSPAISIDQKTTSKNPRSTVGTV
                     TEIYDYLRLLFARVGDVYCPTCGEKISQMTIQEIVDKMLDFPDRTKLQILSPIVRGQK
                     GTHKKVFDNIKKEGFVRVRVNGENYEVSDDIILNKNQKHNIEVVVDRIVIKDGIESRL
                     ADSIETAVKLSDGLVIAQIIDGEEILFSTKFACPEHGIGIEELSPRMFSFNAPFGACD
                     VCNGLGESKEVDPELVVPNKDLSIKQGAVAAWGSTGVNDDTYYSKMIKSLAEHFNVSL
                     TTPFKDLPDDFVEELLYGKDNIIVEFTYESKFGGTRNYKSYFEGVIVNLERRYRETNS
                     DYMRDKIEEYMAERPCPKCKGMRLKKEVLSVLVDGKNIMEVTNLSVNELIDFMENINL
                     TEKQRFIAHEIIKEIKGRAMFLRDVGLDYLNLSRKAGTLSGGEAQRIRLATQIGSALV
                     GVLYVLDEPSIGLHQRDNDRLITTLRHLTDLGNTLIVVEHDEDTMREADYVIDIGPGA
                     GIHGGEIVAQGTLDEIIENENSITGQYLSGKKQILLPETTREGNGSFIEIVKASENNL
                     KNIDVKFPLGKFTCITGVSGSGKSTLINDILYKGVASKVNRLKQRAGKHKEIKGIESI
                     DKVINIDQSPIGRTPRSNPATYTGVFDFIRDIFASTNEAKARGYKKGRFSFNVKGGRC
                     EACKGDGIIKIEMHFLPDVYVPCEICKGERYNRETLQVKYKDKTISDILDMNVEEAVE
                     FFENIPNIKRKLETLMDVGLSYIKLGQPSTQLSGGEAQRIKLAAELSKRPTGKTLYIL
                     DEPTTGLHMADVDKLIQVLQRLADTGNTIIVIEHNLDVIKTCDYVIDLGPEGGDKGGT
                     IVATGTPKEVSKVDGSYTGQFLKKYFS"
     gene            complement(44818..46788)
                     /gene="uvrB"
                     /locus_tag="OE968_000885"
     CDS             complement(44818..46788)
                     /gene="uvrB"
                     /locus_tag="OE968_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HCP7218198.1"
                     /translation="MDFKIKSDFKPTGDQPEAIKSIVDSINRNEKFSTLLGVTGSGKT
                     FTMANIIQQVKKPTLIMAHNKTLAAQLYSEFKEFFPDNAVEYFVSYYDYYQPEAYVAH
                     SDTYIEKDASINDEIDKLRHSATASILERRDTIIISSVSCIYGLGDPKDYKELMLSIR
                     PGMQRDRDDVIKRLIEIQYERNDINFTRGTFRVRGDILEIFPASNDEKAIRIEFFGDE
                     VDRITEIDYVTGKIVGTRNHVVIFPASHYVTTPERIEKAIVEIENELQEQIKFFKEND
                     RLLEAQRIEQRTKYDIEMLKEIGFCQGIENYSRHITGRSEGERPYTLMDFFPDDYLII
                     VDEAHVTIPQVRGMYAGDRSRKTSLIENGFRLPSALDNRPLNFQEFEGNINQMLFVSA
                     TPGPYEIQHSETIAEQIIRPTGLLDPIVEVRPINNQIDDLVGEITKTIEKNERVLITT
                     LTKKMSEDLTNYLKEIGIKVKYLHSDIVTLERTEIIRDLRLGKFDVLVGINLLREGLD
                     IPEVSLIAILDADKEGFLRSETALIQTIGRAARNENGRVIMYADRITDSMQNAIDETK
                     RRRDIQNLYNEEHNIIPKTIQKNIRDSIEATKVAEEEVVYGISDTDDKDEIRANIDKL
                     KSEMMEAAQNLQFERAAELRDKVKQLEEKLEK"
     gene            complement(46975..48237)
                     /locus_tag="OE968_000886"
     CDS             complement(46975..48237)
                     /locus_tag="OE968_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline phosphatase family protein"
                     /protein_id="HCP7218199.1"
                     /translation="MTKVIVLSVDSLFEKDLEFVKNLPNFKSILENCSIVKNINCVYP
                     TLTYPCHTSMVTGVYPKKHGIYHNEKFDPNKENKDWYWYSKDIKAKTIIDVAKENNLT
                     TSSVLWPVMGANPNIDYNIAEIWAPSREDDPRETFERSSSKVIMDGIYNRHCHYIDWK
                     LEPNMDLFGVNCSVDIIKEYKPDLMLIHLATLDHTRHNYGLFNDEVDKALKMNDKWLG
                     DIIQATKDAGTYKDTNFIILGDHGHLRVDKVINPNVLLKSNGFIKVENGEVKDFDAYV
                     NSSGISAQIIVNNLDRLTELRELLEEFKEELFIENIFTKEEASNLGLEGDFEMVIEGL
                     EGISFGNDFEGSIIKDSDIKDYKFAVATHGHLPTKGNRPPFIAFGPNIKGGVVIEEGD
                     LRAHAATILKMFNLKLDGVEKEAFDFIM"
     gene            complement(48300..49604)
                     /locus_tag="OE968_000887"
     CDS             complement(48300..49604)
                     /locus_tag="OE968_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HCP7218200.1"
                     /translation="MKLKRKLATGLAITLLLGSLVGCSNSNDANASKGEKTDSNITKI
                     DFWAPLGGTNGETAQKMVDQFNSEHKDVQVNMLKQKDYYENATKLQAALTSKDQPDVT
                     LLEITQTGTFASAGALVDMSKYFDKTYQERFFSGLLTNSYYEDKFVGMPFNRSTPILY
                     INKDMATKAGLDPSGPKSWEELKDYASKMTNKSEDTYGFETPIDIWFYEAMVMQSGGE
                     ITNGKKVAFNNEAGQAPVKFWQDMMKAGIMKMPPGEDYNAWDVAKQDFVNGKVGMIFT
                     STADLAGLMQQTEGKFEISTAFLPKNQKYATPTGGANLVMLEGGTDKEKEASAEFIEW
                     MTQTDKIVQFSSSTGYLPTTEDATNSEKLQTLYKEKPQYKVATDQLQYAVALPMLNGY
                     KEATDKLMDEIKKGLTDLNANPKDVVSKGTSAMQAVIDKTNK"
     gene            complement(49635..50495)
                     /locus_tag="OE968_000888"
     CDS             complement(49635..50495)
                     /locus_tag="OE968_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HCP7218201.1"
                     /translation="MDIIQPIKKDKVDIKKIASKSIEILILLLLSAIFIFPFIWMLST
                     SFKNPQEMMQLPPTIIPNDIVLENYSTAWHSGPFFRYLLNSVFVTGSVLIVQFLVMVP
                     AAYAFSKIKFKGEKMLFGLLLVGLMIPPQVTFLPVYMMMSKFGFINTYVPLIIPFMTS
                     SFGIFLLRQNFMQISDEIIEAAKLDNASDLKIMFRIMVPMAKPAVITFILFNFIYHWN
                     NYFWPLVMTNTDAIRTLPIGVALLKSSEGITAWNVIMAGNIILILPIILVYIFANKKV
                     KEAFMYSGIK"
     gene            complement(50539..51408)
                     /locus_tag="OE968_000889"
     CDS             complement(50539..51408)
                     /locus_tag="OE968_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCP7218202.1"
                     /translation="MKKQFNKAYLYITPAIIGTLLFIVYPIIKTISLSFKSGSLLSST
                     FENVGLNNYTELLKNPEFIQTITNTAIYTFFMVTISISLAIVLAVWLNKNSIIHNLTQ
                     SIIFTPHVISLVSVAVLWLWIMEPQYGFLNWILSTLHLPTSKWLSSESSALMSLILIG
                     IWKTLGYNILIVLSGLKSIPNYIYEASKLDNANKITNFFKVTLPLLSPTIFFLMITTT
                     TASFQVFDEISIMTQGGPVGSTNMLSYYIYESGFIYYDIGQASAASMFLLAIVMIATY
                     ANFRLLSKKVHYQ"
     gene            complement(51392..52462)
                     /locus_tag="OE968_000890"
     CDS             complement(51392..52462)
                     /locus_tag="OE968_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCP7218203.1"
                     /translation="MADIRLENVTKSYNKKNTVIENLNLTIEDGSFTVLVGPSGCGKS
                     TTLRMIAGLEDITSGRLKIEENDVTKTDASKRDIAMVFQNYALYPHMTVRENIEFGLK
                     NKKVEKEKREKLITEVIDVVGLREYLNVKPGNLSGGQRQRVALARAMVKNPKVFLMDE
                     PLSNLDAKLRNQMRTELIQLHQKLKSTFVYVTHDQVEAMSMADKIVIMNKGKIMQIGS
                     PKKIYQNPKNLFVAQFIGSPCMNILDIKNDIKFGFRPEKATLESINIDGKNDDVFSLF
                     GKVVTKEVLGNETIYCLSVLNREIRVKTENDIFDIGRTLRISVLEKDLYYFDKNGERI
                     EDVKVCKSMYSKIKGDIYEKAI"
BASE COUNT        15508 a        10358 c         7532 g        19507 t
ORIGIN      
        1 gttacatacg aaccagcgtt ataggtggaa tggaaaaata ccaaatcgcc agcctttgcc
       61 tgcgagagtg gaagatgttg ggtagcgtca tactgggctt gtgccgttct cggtaaggag
      121 ataccagctt ttccatagca ccattgcgtc agtcccgaac agtcaaagga agtggttgga
      181 gaagaaccac caaacacata tttccaccct tgatatttca acgcttcatt cattaccttt
      241 tgtgccagct ctcccgatac ctgcggaaca gttaaatact gattgactaa ttccacatag
      301 aacatatttc catagccata ccgccagcct ccgttcttcg caacggctat cgggttggta
      361 taggttactt tctttccacc cgatttctca cgggcgaagc tctctgcaag attaaaagtg
      421 tgtttctttc cgtttcctgc cacatagccc acatagccac cgccatagtt ataggactgt
      481 atcgctacat tcaaatcgtc gatatcttga tttttgcagg aagaaagcag ggacgcaaaa
      541 tacttacacc cctgcttgat tgagctttcc gtatctaagg aactaggcgg taaaccaaga
      601 ctttctgaac tctgcataac atcttctgcc gtaccgccac tttctacttg aatgatagcc
      661 agtagtacat tgacgtactc ggagataccg ttttctctgg cgtatttttc taccatagtc
      721 tgatgtttca aaacttctgc ggataagttc atacccgtaa tgccagaaga aaagttgctg
      781 ttttcgtcgt cgctgtccgc actaatcagc accccaaaga aaagcaccag agaaaagaga
      841 ataggaaaca gacttccaat gatagcgata tgtttcagtt tcattttttc ttctgtcctt
      901 tcttcgttac aagattacgg attttctctg tggtctgctg gttcttctgg acagtctggg
      961 tctgctgaac ctttgtccta cggtctttgg tgtaattctg gcgtgtttcc tttgacacgg
     1021 taactttttc tacattctgc ctatatgtcg attgggtcgc tttcccgtca ggagtactag
     1081 aagatagcgg acgttctttg acaccgcttg tcttaactgg ttcgcttgct ttcgtagtcg
     1141 gagttgtggc agggcgtttg acttcctgca ttttttccgc acccgtcttt gaaacggttg
     1201 aagctgtggc tggtcgctca tggggacggg tagctcccgt tgtcgctgat ccgtcagcct
     1261 ttcgctgtgc ctgccttgct tcttgtgcct tttgaagctc catacgcttg acagcgatac
     1321 ttttcttatg ctgttcctgc ttttccaagc gtcccgtctg tctggactgc tgttcctgca
     1381 ccataccacg cttgaaatca gacacgctgg actttgcctt ttcctttgcg gaatacaccg
     1441 cataagcggt ctgtgtgggc atatccttga tattctcttt gacagcgttt gccttgtctt
     1501 tcactttatt tttcgtatct aagacagcac ccacctttga gcctgcacgc tgtcccatac
     1561 tggaagtggt attgccccga ttttctttag aagccgtatt ttttctttcg gctctcttgc
     1621 cagcaacggc acttccagct accgcaccag ccacaccgcc cgaaataccg ccagcactta
     1681 cagcccttgc aatacggtgt tccatacgcc tagcccgatg tcgcatgaac agatacggtc
     1741 tgcggaatat cctgcgtccc atgctttgac tgtcgccagc gttgagagaa aacatactca
     1801 ttaagtcgcc cagcttcata tagataccag cgaaacatac tatctgcaag aacgccacca
     1861 tgaaaaacgg atagtccgtg gatatgttat aaaacatact ggaaatgcta aacgcaaccg
     1921 ttacaatgag cgttattcct gcccgtgtca ttatggtatt aaataccctc acgattgcct
     1981 gctttgccat gctttcatag ctcggtatca tggaaagtag aaagctgata ggtaaaaaca
     2041 tagcgaagat aataaaaagt atctggctga acaacatcat acccgtaagc aagaatacaa
     2101 atatcgtaat accaagatta aagaacaaga ggaagaacac catacctaaa cggtttacca
     2161 cctgcggtat cgtcagattg ttgttgtcgt tgtcctcgat ttctgttttc acgacttctt
     2221 ctctggtctt tccgtcctcg tcctctggac ttgccgatac gagagcttcg acacggtctg
     2281 tcccgatttc ctctgcgttg ctgtttccaa actgtaagag tagccacggc tgttgtactt
     2341 gaatagaaaa taggctgtcc cgtatcaagt ctacgctgtc cttgccctcg ctgtcagagt
     2401 tggggagcat gatttttgtt cccaaatcaa gcgaagcggt actgatgtct gatgaaaatt
     2461 catttatctt cttgatgtag tcgggagcgt aggcaataaa cgaagcggac agcacgaaca
     2521 ccaccacaaa gttgataaca gcgtgaagtg ccttgctggt ttcccgtttt atcagtcccg
     2581 tataggcaac atacattccc accactaaga taataagaag caggaaacca acatagaagc
     2641 ccgtagaaga aaagccgttc tcggtaacgc ctgcaagggt ctgtatgctt tttccgatac
     2701 tgtctgccat atcgttaata aaatcaagtt tataggcttc ctgcaccaca tagccagttg
     2761 cattgcttaa ataaaggctt atcgtccaga caaagttggt aatgcagtaa agcccgtact
     2821 gtaccgattt tccgataccg tccagccagt tccacggaag ccacgaccag ctattatcga
     2881 cgaaaaaatc aagctggtag ttggaaagcg gatattttga atatagattt tctgcgttta
     2941 tggtatcgtc cacaagcccc gtcgcatgag ccaccgtccc cagaagtgaa agcaggataa
     3001 gggaaagtgc caccacgaac agagccattt tgagaaagtg aagtatcttc ctttttgtga
     3061 acgcactctg tatcctttct ttcatcactc cacctcattt ctctgtacgg gcggtctagt
     3121 atcaaaggcg tgtagtaatt cttcaaagac tgggtgtatc tgcaccacac cgacacgccc
     3181 gtataagtcc tgcaataaac attgtccgtt ctccaaatca cgcaagcgtt tctggttgtt
     3241 ttcgtcgtcc ttgtcgatac cgaaaaattc taaggtctgc tttatctcgt tgatgtcagt
     3301 agaacgaaat gcaaacttca aaccgatatt gtttttcaga ctttcctttg acacgtcata
     3361 ggcagactgg gtaacgaaat aaacgcctgc ctgcatagct cgtccagcac gaaccagctt
     3421 atttgatagg gtttcgcctt gtgccacatt taagaacgcc cacgcttcgt ccaaatctac
     3481 aatcttaaaa atgcttctgt ccgaatggat aaaatcaagg gcaaaggtac taatcacaat
     3541 cagcatagac accgacaata attcaatggt cgtgtattcc tcaaaagtgg tatctttatc
     3601 tggcagtaca aggtctgcta cttgaatgat attgagctgg ttatcaaggc ttatagcatt
     3661 ttctaccgtc ccgtctgaaa acagcaggtg tgcaaagtcg tagtccgtga agctgtcgat
     3721 atggtctgcg atattgcgtg agatagcggt atcttctttt ctcaattcct caataacgtg
     3781 taacagtcct ctattttcac tctgggtaac agaacgcacc gcttttcgta acacggggaa
     3841 tttttcgccg tccctagagg aaatacccgt aaggaatgtt aagatgtcga ttgccagact
     3901 ttcagcgtct ttcacattct tcataatcac aaatgggtca agaagtcctg cattgtcctt
     3961 gtcgctggta aggtttacga tattgatttc atgggctatc tctgggagcg tttctttcca
     4021 gttgccacgc tcacttttag ggtctaacag aagtgcttga ccgccaaaca gcaccgcata
     4081 atatacaagt agattgttgc agaatgactt tccaccgcca agacttccca caaaagcaga
     4141 agcaagggca ttagtaactg tgccttttac tccctgcgaa gctaaagacg gttgcaggta
     4201 cacatttctt cccgtatcaa cggaatagcc catatagata cccgtgtttt cccctaactg
     4261 ctgggtcgca ccaaaaccaa gcccagccaa gaagtctgac tttacatact gcacatagtc
     4321 attgatatat cgcttgctgg caggtaaaaa ttcagaatga agtcccaaca tatcgccagc
     4381 aggacgcacc agttttacat tgaggtcgtc gtaaaagtcc ttgacttcat cacaacggcg
     4441 tttcagctcg tcaagatcgg gtgcagacac ccgtatgacg tagcttaact tatacatact
     4501 ttctttgctc tggtctaaat cggtttccag ctcgtccacg ctgtctaaag cgtccaccac
     4561 atttgagctg gtttcacttc ctgcttgata ggcgtgatta tccaaatctt tcaattcctt
     4621 tttcttgttg cggactgtcg ttaatgcctt acggttctcc acgatttcta cattcataga
     4681 agtatcaacg gggaatgtga attgctgttg ctggaaatag aagatttcag aggacggaaa
     4741 atccaactcc ccgacaatta cattgacggt aaaataggac acatagcttt ccttgtcctc
     4801 atgttccaat cgtaaatacc gctggctttc ctcaatcaca caccttgtcg gacggataag
     4861 gtcgtagtat tttatcagcg tttctttctt caatttcttc tttggtagct ggtactcata
     4921 atcttcatag gcgataccgt ccctgccgta aagatgttcc atgagatacc caaaatcatg
     4981 gatttccaag cgacgcacct taaagcgacg ggagatttta ttttccagta acttttccat
     5041 tttcatgtaa cggttgattt catcattcgg catggaaaca aaatcattca tcagcgtgtg
     5101 gttcacttca tgaagaaatt ccttgaacgt cagccatgcc gattttttga tgttcttcag
     5161 attgagctgt tcttccgtaa ccatgagctt aaagccaaga aaaaagcggt agtccacttg
     5221 attgtcccca atcattgata ctaacgcttc ggtctgttcg tctatttttt ggactgccac
     5281 ctcacgaagt ttgcctgtta ccagtttctt tgactgctcc tgcatacttc taatggagct
     5341 ttctgtggca atctgcaacg catgaatttt tccctcacgg gactgtgcga ttagctgtcg
     5401 aaaactgtca tgcacgataa atttctgctc tgcggataga aaagaatagt tgtacggtat
     5461 catctcatag taggcgaaca cctcattgtc cttgttccag acaaggttat tgtcaatata
     5521 ttttatcggg aacatagttc acactcctta ctgccgtgat tgtttcattc aatatctgct
     5581 tatgcagttt tacggctttt cctgcataag tgattttagg tcgcaaggca taggttatct
     5641 gtgatttcaa aaagctgtac ggcttctttc cgtcaaaggt tttctgcgac ataaaccaag
     5701 tgagagcaac gggaataccg aagtatttga gaaatgctcc ctcaatcatg gaaagtgggg
     5761 gcatatcccc aaacagaatg atgataaatt ccgtaatcac aaaccatgta atctgtgtaa
     5821 aggtaacggg aaagggtaag ttaaagtcat tgattgcata taagactttt tccacgttcc
     5881 agatacccgt gtagctttta atctttttca agttctttca gcccctttcg taagttcttc
     5941 aaagagaaaa ggacagccat tttcagactg tcccttaaag agaaatacgc tgtcagtagc
     6001 aacaatgctt gttgctgatc ttccagcgtt aatatggtat ctcacagata cctcggcttg
     6061 tttcaatgaa tcgaccaccc atatccaaat ctcgcccgta ggcttcatag tcaatatagt
     6121 tctgtaagtt agctggaatg tccccaagtg cgttcaattc gtctatgtag tagtaggcaa
     6181 catctgtcat ggtttcacaa tcgggataaa aataaatatc gtccttatgt tccacgactt
     6241 cttccagcgt cccatagtgg ctgataaatt cgtccagaca ctctacgata tagtcgggaa
     6301 gttcctctat catttcatac atttcattga gttcttcaat ggaaacatat tcccctatgt
     6361 cgataggaaa gttgtcggta tcatggacag cgtattcttc gtactgttca ttcaagccga
     6421 ttttttcttt tacatcttcc tcgtcaatag ggaaagtgaa ccacgcaccg actaaatatc
     6481 cctcattgta tctgccaaga ttagcaatat aaaccgccat atcatcaatc ataagcacca
     6541 cctcatttcc tattctggca gttcaaagat actgttttcc gttacaagat agcgtttgtt
     6601 ttcaagtaag tgagaagcgt aggcttcaaa atcgaaatag tatgcttgac agtcctcgga
     6661 taaatgtttg aatgtcgggt cgttcatcag cttttgcctt gcaacatcta tcatgctttt
     6721 acagtcgtga taaacggtaa tcacgttcct gcaaatataa agtgcttcta agttctcaaa
     6781 cacggtaaga agttctacat attcttcctg catatcggct gatagctggc ggtacataaa
     6841 atctaattcg ttaagctggt acacgctggt gtgttcgtgg acttcatcag cataaggcaa
     6901 caccttttcg ataatgcggt aatcttgact ttctgcaccg acacctaact tttcttcaaa
     6961 ctctgcaaca tctatcggta agtcaaacca gtatgatgtt gtttcttcgc catttgttct
     7021 tcccgtttcc accagtaccc ttgtttcctg cattgttcct cacgtccttt ctgttgtttc
     7081 atcacatctt ttaaggtctg gtatgacata ccaaacacat atttagaaaa atctttcaac
     7141 tgtttttctt catagtcggc agggttcagc cgtttcattt catgccacac cttacgcttg
     7201 taagagggca ggtcggaaat gtattcacag ccgacttttg cctgcatatc tttaaaaata
     7261 tcgttcattt catcactcca atctgaaatt taggtaagaa aaaagcagtc aatcctaaga
     7321 ctaactgctt tgtgtgtaag tatgaatttg tttaagtgta actgatttac catgtgtact
     7381 cgtaaagttt actgtatgtt tgacttttaa ataaatatat acaatcaatc atttgtaact
     7441 tgccgtcttg ttcaaattta cttattatca gattatcttc atagatatat gctaagaaag
     7501 tatcatactc tgcatagtat ttttctctaa aaagatttga ctctctaaaa tctttttcta
     7561 aagcaattct tatactgtct aaagcatatt taaagttata acaagtatta aaactaaact
     7621 tgtatggaaa aaagaaaaat aagtttttct tgaaagtaag caatttcaca taggtttgta
     7681 tatcaaattc aatcgttcca tactcatatt tctctgtaag acaagaatgt aaactttcac
     7741 aatcataatc ccgcaacgaa gcaaataacc tagttacagt catttgtgta tttggtcttc
     7801 tcggtggaca cttaccaatt acaccatcac agaatttctg tatttgacca gtaagttctt
     7861 ttgaagcatg aagtcttgtt gtgctttcaa gtaatttaaa gtccatttga taattaggtg
     7921 agttacaatc acattctcca tgattttcag atttaggtgg tacatattct gcaaaatttg
     7981 atttttctct aaaatatatt gatttattaa ctaattccaa caagtatttt tcataattac
     8041 aattttcttc atctttaata aaatttttgt ttatgaatac tgcatgtaaa atatccactc
     8101 tcatttcatc tgaaatcata agcactttta ttcctttcaa aaaataattt atcgtaccca
     8161 cattataaca ttctcatatt acagcaacaa taaaattcgt tatgctccaa taatcttatt
     8221 gaacagctct aacagtacat ctttcacacc gccagcgttg aatactaagc cgacagcaat
     8281 aagggcaact accaagaagc caataagttt tgaaaactca cgcttgaacc ctaagtagat
     8341 accgataacc acaatcgcca taagcactaa gctctgtgca tttgataaaa accattgata
     8401 caaattttgt ccgaaattca tttaattgtc ctcgctttct tctaattgtt tcatttcata
     8461 gtcagcttct ttgctgatac tcaaaataca catcaagact acgccgatac ccattcccat
     8521 agataccagc aggaagtctt ttactaattc ccacattttt tatcactcct aactttccac
     8581 caaatctttt gcaggggtcg tctgctgttt gattatcatt tcatgctttt cactcaagat
     8641 tgcctgcttt tcaatcgttt ccatgtagtc tgtaccgttt cccttatcaa tctttttcag
     8701 cattttcaag gtcggtgcta cctgtctttg tacccaacgc aatgtgcggt ctaaggtgta
     8761 aggttctggt tttgtcgtca gtttcagact ttgccgatta tcgccaataa accaagccca
     8821 gcggtcattg agtttccagt catttttccg cttgtctggt tcttcatcaa taaaccgcac
     8881 atactggttg atgatagaaa aagcggtctg ctctgcgtca tagtaggtca gcaaatctcg
     8941 tactgcatag taagcacgtt catttctaag ccgtatctca aaacggttga taatgtcggc
     9001 ttcttccaga ggtgtaccta atttgacata ctgctcatag tccttttcat agatacagaa
     9061 atacacatct gatttcagcg aaccaagata aagggtactc cccatatatt ctctgtcgtc
     9121 ctctctgtgc ttgataagct cgcccgactg gtaatactta tagcttctgg actttccgat
     9181 atattcccgt ttcctgcatt tctccgcaag ctctggaata tccaaaatgc ccgtatggtc
     9241 gttgatagca aggtcgatac gcttcataat gcctccgtct atgagtgcgt ccataagaaa
     9301 gtcataccag cttctttgct gtgccagcag gtaactttca aactgcctgc aaccccgacc
     9361 ctttaactct aaaaggacac ctttttcttc gtcagccgac gtatagataa agatgtcccc
     9421 taatgaataa tgctccgtat aactgtaatg tccgtaatct tcatggagca tataattgat
     9481 attcagtttt aatatgtctt tgatgatgtg ctgtatatcc agcgtgggaa aacgaatttt
     9541 cacataatca aacagcatgg taagcggtgc ttctggattg aaccttgcca gttctttatg
     9601 caaagtttcc agaagttctt ttgacggctt catttttccg ctttctatct tgtttagata
     9661 ttcccttgtg ataccagaag ctaccgccag cctgccttgt gagataccgt aagcaatccg
     9721 cttctcccgt aattctttta tccattgttc ttcattcaga accatacccc caatctgtca
     9781 agtgtgaagt tttttaaggc gacttcacag ccgatttttg ctaggaaacc atgccagaag
     9841 ccttatgttt cctatgtttt tttgtctatt gtctatttgc aaacgtaccc ctctgttaga
     9901 taccgagggg ttttacctgc tggcgtggct tacgccacac cagcaacggc tagtccgagc
     9961 cgtcgccttt cgcttcgcac gtcgccgtcc cgtcctgcct tgcttgtgca agaaaaccga
    10021 ttgtctgcaa aaaatcatgt cctttcggga ctaaaggcgt gtaaaattca cttatgacgc
    10081 ttgttcccac atcacaatag ccacgccctt tgatacgctt ttggaaaaac tgctttttca
    10141 catctgaacc aaacagcata ccgtaaccta actcgctgat acgccccaat cccacacgta
    10201 aattgaagtt atctctgata ccgtccgaga aatattttgc gtctggacgc tggcaggcaa
    10261 cgataaggaa ataacctgct tgtcgtccta acatgacgat tttctttaac tggctaagta
    10321 agcccacact ttcttttgtc cccagcattt caaaaaacgc cacatattca tcaaagataa
    10381 gaaagcaggg tggcagtccc agataggcgt aattttcgcc cgtcttatag ttcgggtgtc
    10441 gtttcatttg ctcgcttcgc tgtaccatgc cctcataaaa agcattgaca cagtctatca
    10501 tttcttcttt ggtgtgatac acgtttccca tgactgttcc caagtctgct aagtccgcat
    10561 ttttcgggtc taagatgtaa aggacagcgt tggtatgcag tagggcttca atgagcgtca
    10621 gaagaaaata tgttttaccg ccaccagtcc caccagcaat cagagcgtga gggagtgcgt
    10681 catattccca gacaagattt ttcatcagtc taagacagcc gttctctgcc cgtacttcat
    10741 caatggtaat gcggttcgct atcatatcat aaagcagggt atattcgata tagccgtcat
    10801 gcagggtctt gtcggtcagc tcacaataca agccactttc caatttatcc tctaaccgta
    10861 aaagctggtc ttgatatttc cccagcgtaa tttcacagcg gatatgaagc agtccctttt
    10921 ccatttgata ataaatcttt ggaaaccaga cgattttttc ccttgatctg ctttgcaggt
    10981 cagtaaaaaa aacgctgtct tgtacggtat cagcttcata ccacttgttt tccagtatca
    11041 ttcgtgccag cttttgacgg tgcagtagct ttttgaaact gtcgtaacag aagcggtaat
    11101 acagaaaagc gaccaatgca caaacaccag tcgctatcag tatggttatg aagttgtaaa
    11161 gggaaagcgt aaagccattg tctaataagc tgaaatgttc ccagtcggta cgcatgagct
    11221 gttttgtatt taatagcagg ataaccgcta cgaacacaaa caggagtgtc cccattgaaa
    11281 agcgatagac aaggttctta tcgctggctc tgatacggtg tcctttgttt aaaatcattc
    11341 tcataaatca atcactcctt tctgggtatg aaaaaagcag tcaatcgtat agactaactg
    11401 ctttgtgtgc atggatatga agttgtcaaa ctggaattta acgttcactc atatattgtt
    11461 ttatttcatc agaagtcaat tttcgtactt ctgtatgtgg atattcttta tactctccaa
    11521 cattaaacac aggtgtcatt tgtttgcatt tcttgtcttt attctttttc aagaatagat
    11581 gtaaatcctc attcccggcg aatattttat aagatactct gcctttactg ttctctatct
    11641 cataaatacc acatgaactt ttcgttgtat aatcggctgt tcgtaaataa agttttgcaa
    11701 tttccaatga cttaaaagga aaattccatc tttgtaatcc tctgtttggg tcatgttcaa
    11761 tacaaatgca acgtccacaa gttccacaaa tatattgagt gtggttttct aagcagtcca
    11821 agggatttag taatggtgtt attctatttt catcagagta acattcttca cacatttttc
    11881 ttttcgctcc ttatcaaatt ctaatttgtc gctttcttca tacccatatt ataacagttc
    11941 cgtatatcct ctacaacgaa aatctattca gcaagtctat tttttcggtt gtccctgcgg
    12001 tgtatggttc tgtgaagtgc ctgtgttctg attgccttta ttcttcagta caatatcttc
    12061 tgcctttaca taccagtcca catctgcacc cgtataggtt tttcgtgata ccgtatcggc
    12121 tacgggattg acaagctcca cgactgcatt gtaaggaaat tcccttaacg gtacttctgg
    12181 cggtacggac acggggataa ttccaccatg cagactgcac ttcaaatcat agatacgctt
    12241 tttaagctgg gtactcggtg tcccgtcctc attttgcaag aacacatcac gcaccgctgt
    12301 aaattttaat tctccaaatg ttttctcttt gtcaatgaca aatccatttg ataatctcat
    12361 aaattcttca ctcctttact tttcttcaac tgctacaata tcatcagcta ctaatacata
    12421 atcggtatgt cccacatccc cgattgcgta ccctctgccg tataacttcg gattgacaag
    12481 ttttactttc tgttcatact tgaaatgctt ttcgccagcc tgcacgggaa tttccaccac
    12541 aacattttcg cctttctgta cgtcagaata aaggttatag cttcgtctgg ctatgacctt
    12601 gcggttgttt ttatcccttt caaagatagg ctcgctttcg cctgcaaatt caagagttcc
    12661 aaaagactgt gccatatctg gcacgacata tttcatttcc atattgtttt acctcgtttc
    12721 tttctatatt tgataagttt atgattgtaa ttttttattc tggcttgtct gccgtttgac
    12781 agtttcggcg gagaacgtga tttttctttc atcataccgt taccgcctta tgattttttc
    12841 attgtacggc gtttgtaaag atatgttcca gccagtccac cagcagatgt aagcaacatc
    12901 acaagaaatg ccatgacatt tgtactgtcg cccgttttag gactgtcgct aggtctgttt
    12961 ggcttttctg gtgtctgcgg tgtttcgagt ttctctggga cttctggttt ttcattaaaa
    13021 gtaatcgtct gtccctcgtc ctcaatatcc ttatgctcgg taactttctt cggctcgtct
    13081 ggattgctta aatcatacaa ttcttcaaaa gttacaagct gtttgccgtc aagggaagta
    13141 gcgtcaaagg taaaggcaac ttccgctttc atagtttcgc tgtcagcggt aaaggtgtaa
    13201 tcactttcca cacgtttccc attgataaga agttctgcat tttcttcttt caacatctgc
    13261 cagcctacaa gtttgtactg tgtaccgact tccaagccct ctaaggttac ggtatcaatg
    13321 attgtaacgt cttttccagc ttcaatctct ttgttgccgt ctttgtcggt agcagtcgta
    13381 tgtatcttga tgatacgttc tgtaatcaat acagtttgtc cgtcgtcctc aatgtctttg
    13441 tgttccgcaa ctttcacggg ttcgtctgga ttgcttaaat cgtataattc ctcgaatgtt
    13501 accagatttt taccgccaag ctcggacgca ttgaatgtat aagaaatttc cactttcatt
    13561 tcttcatcat cagcgataaa agtatagtca ttttccacac gttttccgtc aatgataagc
    13621 tctgcatttt cttcctttaa catctgccag cctttgagct gatattttgt accttttgta
    13681 agcccgtcta atttgacagt atcgacgatt gttacctctt ttcctgcaag gatagtcttt
    13741 tcgctgtctt tgctggtcgc tgtggtatgg atagagattt ctttttcgta ttcatcagtc
    13801 aaagtcccta aatcaatcac aaggttattt cttgatacca cgatttcaaa aggtgggata
    13861 agttcaaagc ctttgttact atcgcaacgc atttcttcaa tgatgtaagt atcataaggc
    13921 aatgcacctt tgctgtcgtc tgcttcagaa gttccaaacc acacaccgtc ctcgctggtc
    13981 ttgcctgcgt tagtattgtg cttatgagaa gtccattcag cagaagtgga gaattgcccg
    14041 ttatcatcag taactacaac atgactttct cccgtcgtct tgcttgtgat cctaaaggga
    14101 acatcagcaa gacgcttgtg tgtgcctgca ccgattttca ctccctcaat atccccacgc
    14161 ttaatctgat tgtagataga gtgggcttcg tcggttaagt ccacgatttt tccattctct
    14221 gtgattgcaa agtcaatcgg cttcgcaccg tctgtcaagt aaccgtcggg agcttcactc
    14281 tcaacgatac ggaatttccc ataaggtaaa aggtcagcag aagtagaagc cacaccctca
    14341 atatctgtac gaattgtctt taccacttca tttttcttat atagcttgcc ctcaaccaaa
    14401 acagaattgt catttaagga aatgacgtca aaagcagtat ctttcaaagt ggcacttcct
    14461 tgtggtttgg tatcgctcgt ttctaaatct cttttctgaa ttttcacacc gccacggata
    14521 accttgtctg atacggaaaa ctggttactt cccgtcaata cagcaaggtc gccgtcctct
    14581 gtaatttgtg taaggtataa gccttttatc tgttcagact tatcgccagc ctgcatatat
    14641 gcaccgtcca gcaagtagcc gtttggagct tttgtttcct caacagatag tgttcctaaa
    14701 ggaagaatcg ctttgccgtc ctgcatatag aagctgtcgc cagatacctt gtaagcgtcc
    14761 gctaattttg tgatgtagtg agttgtcccg tcactgtctg tttcagcgat tgtctttgta
    14821 acccatgtac gagtagcttc ggcagggaga ttgtctttgt tatagaagcc agcataatac
    14881 ttccatgtaa actctgcacc ctctaaagaa gcgtttccct gcggattgtc tttctgcgtt
    14941 tccatatcaa tcttgaaaag ctcaatcaag gtgtccgtta cttttggtgt atctgatacg
    15001 ttcaaggtcg ctgtctttcc agcttcaact tttaaggaat acacggttgt atcaacttta
    15061 tatcctgctg gtgcggataa ttccctaata tagactgtac ctgcttttac ctctacaaca
    15121 tctgtatttc cgtttttatc agtcgtaagg gtggcaagct gtttcgtgca gtccttatca
    15181 gaaaagacac cataggtcgc accagcgatt gagtaattcc cgttaccgtc tgtaatgctg
    15241 gtattactgg aagtcttttg cagttttgca tttccgacat ttaacttcgc ccagaattgt
    15301 cccaattcct gcccctcgcc agagtagata taaccgccac attcatagcg tcctttattt
    15361 tctttcacaa aggctttagc accagcgaaa acttcgtcct gagttgcttt tggtatttca
    15421 tcataagaag ctcgcacgtt gtcgcattgc cagccaagat gtacgctcaa tctctgccag
    15481 acaacacatt gttccaacag atagacttgc ttgtagttca attccttgtg tgcttcgcca
    15541 tactgtttga catactctaa ggataacgcc acatctgaaa tctggtcggc actcatacgg
    15601 gtgcttgcgt cagctctggt cttgtagcca ttcttaaaat ctgtattgat gtctatacag
    15661 taagcgtcct cgccctcaac agtcaaatgt ccctcgttaa aggtagaacc aatcgaaccg
    15721 tcattcatta ctttttctac gataccgaca cgttcctctg attccgtcca gtattgcttg
    15781 ctttctgcat ggacggcggt actcggtaaa gcagtaacga cagtcgcaaa ggcaagtact
    15841 cccgtacaca atcgtttcaa tatctttttc ataattctaa atgctccttt cattttgggt
    15901 aaaaaaatag acgctcaata ttgaacgtct tacattgaaa agggatactt tttacaagta
    15961 cccctcaaat ctaatattta attgtttgtg ttcccacact ctatatcaac aactactgaa
    16021 acattgatat agttttttat ctctttattt ctgattttat cgccctcgct cgtaaagact
    16081 atatgcttaa aaaagtgcct aaaattaagg atttctacat agttcgtctt tgtagcaaca
    16141 cacaagtctc tatatgtgta gaatgaggga acatatctac aggttgtgcc tcaacacatt
    16201 taaatccgtg aacatttaga taatctaaat cccttgctaa agtagaagga ttacaagaaa
    16261 catagacaat tctttccgga ttcattgaaa caatagtctc taataccttt tcgtcacatc
    16321 cctttctagg tgggtctaca acgactacat tggcagtctt accctctcta tacatcttag
    16381 gtacaatttc ctctgccttt ccaacataaa attcagcatt atgtatattg tttaatttag
    16441 catttatctt agcatctttt atggcatcat ctataatttc tattccataa acctttttag
    16501 ccttttgtgc caaaaataaa gatattgtac ctatcccaca gtaaatatca aaaacagtat
    16561 cagtatcatt taaatttgca tattcaagag ccttatcata caatacttta gtttggacag
    16621 ggtttacttg gaaaaatgat aatggtgaaa tctcaaacac taagtctcct atataatcgt
    16681 ttatttttcc atctccatat ataactatat tttctcttcc tagaatagca ttcgtatctt
    16741 tttgatttac atttacaacc aaagtcttaa atccaggtat attttcctta agcactgaag
    16801 ctaattcttt aagatatgga agtttgtttc catttgctac taatacaacc attacttctt
    16861 tagttgtaaa acctattttt gttactaaat gcctaatcaa ccccgtgtga gtcttttcat
    16921 catatatgct taccttatag gcccttatat atgtttttat tattttaaca attttatcat
    16981 ttatctcatg ttgtattacg catttttctg tcgatattac atcatgagtc ttctttttat
    17041 agaagccaat aattggaata ccattattct tttgtattgg aaattgtgct ttatttctat
    17101 atctatatgg attatccatt cctatagtgt catgaacttc tacatcctct aacttaccta
    17161 ttctcgaaag tacttgttta acttcatttg ttttcatttc aagttgttta ttataatcta
    17221 agtcttgtat ctgacaccct ccacaatccc taagattgtc actacacact cttttcaccc
    17281 tgaatggaga cttttctatt atctcaacaa tatctcccac agcataattt ttctttactt
    17341 tattaatcct aactttaact ttatcatgta ttaatccgcc ctctacaaaa actgtaatac
    17401 cattgtactt tcctactcct actccgcctt gaccaatgtc tactatatct acaatataca
    17461 tctcgttttt cgaaagcata aatcaccctc caatcaatct attatattta aatctttaca
    17521 aacttttttc tttaaattta tattaaaata ttgctattaa ttaaactata ttttttacta
    17581 agctacaata ttttatttta ccaaaaaaaa aggagcttat aaagcccctt agtaaataaa
    17641 tttattattt ttcttataaa actctagttg aacctctata taccacgcct cttgatgcat
    17701 ccacagttac aacttctcca tcttttacta gatttgttat atcagctgca gacacaataa
    17761 ctggtatatc taaatttata cctacaatag ctgtatgtga tgtcattcca ccattctcag
    17821 ttactacagc tcctgctttt tctatataat tgttcatttc agcatcagta gcagtagaaa
    17881 caagtatgtc gccttcatta aagtctacac aagcatttcc attctttatt atacgaactt
    17941 taccttctac tgtttgagta cctacaccta taccttgcac gatttcttcg cttattacat
    18001 gaacctttat taaattagta gttccactta ctcctactgg tactccagca gttataacta
    18061 ctaattcccc attatctata taatcagctt gtctagctgc ctcaattgcc ttttctataa
    18121 cttcatctgt atttcctgca acagaagact taactggata tactccccat gtaagagcta
    18181 atttattcat agtcttttca ttatttgtag tagctattat tggagatttt ggtctgaatt
    18241 tagataccat tctagcagta tatcctgaag aagtagatgt tattatagct gatgcattta
    18301 aatctactgc tgttgtacaa gttgcatggc ttattgcatc tgttacagta acattgttag
    18361 taccattttc ctttagtaat ctatcataat ctaaagtctc ttctgttctt tttgctattg
    18421 tagccatcat ttttactgcc tctacaggat attttccagc agcagtttct ccagataaca
    18481 ttatcgcatc tgttccatca tatatagcat tggcaacgtc tgtaacttct gctcttgttg
    18541 gtcttggatt tcttatcata gaatcaagca tttgagtggc agtaacaact ggctttgcta
    18601 attcattaca tttttttatc atcatttttt gaactattgg catctcttca gttggtatct
    18661 caacacctaa gtcacctcta gccaccatta taccatcaga aacttttaat atttcatcta
    18721 ggttctctac accttcttgg ttttctattt tagatattat ttgtatatca gttgcattat
    18781 tgttctctaa tacttctctt attgctagta catcagatgc ctttcttaca aaagaagcag
    18841 ctatataatc tattccttga cttattccaa actctatatc acttatatct ttaggagtta
    18901 ttgctggtaa atttatctta acaccaggta catttactcc tttatgattt ttaactattc
    18961 ctgaattttc aacaacacaa actatatctt ctccatttat ttcttttact cttaagccaa
    19021 ctaaaccatc atctattagt atagaatctc ctgatttaac gtcttcagca agacctttat
    19081 agcttactgt acacatttct ttagtcccca taatatcttt catagttata gtgaactttt
    19141 gcccttcttc taaaaatacc tctgggtctt caaagttacc tgttctaatt tctggacctt
    19201 tagtatctaa taatatagca actggcttat ttaatttttc tctaactttc tttgccatat
    19261 caattctttc tttatgttct tcatgcgaac cgtgagaaaa gttaaatcta cacacattta
    19321 gaccattttg cataagttga gttaaaactt cctcactttg tgatgctgga cctagtgtac
    19381 aaacaatttt tgtcttcttt acattattta acatatttgc tcctcctgag atattattcc
    19441 acagatttat ttttaatact aaaacttata tagataatat ttttgccatc tcataagctt
    19501 ctttatcaaa tactttcttt tgagctaaag cttcacttat ttctaaatca attattttgt
    19561 tttcttttat tcctacaact ctagctgatt ttccatctaa taataattct actgctctta
    19621 ctccaagtct acttgctagt attctatcag atacagttgg gcttcctcct ctttggacat
    19681 gccccaatac agtgactctt aaatctgctc ctgactcttt tttaagttcc ttttctaaat
    19741 cactagcact tccgactcct tctgctaaaa cgattatact atgtctctta cctctttttt
    19801 gagtagtctt taatcttaga gcaacttcat ctactgtaat ttctacttct ggtactatta
    19861 tagtttccgc tcctcctgca agacctgcat ataaagctaa atctccacag tgtcttccca
    19921 taacttctac tatgttaact ctttcatgag atgatgatgt atctcttatc ttacctatag
    19981 catctataat agtattcatt gcagtatcaa atcctatagt ataatctgta tatgctaaat
    20041 cgttatctat agttcctggt atgcctatag ctgggaatcc taagtcacta agtttttggg
    20101 ctcctgcaaa tgaaccatct ccaccaatta caactaagca atcaatttta tactttttaa
    20161 gaatttttac tgcttttaat ctaccttctt ctgttttaaa ttcttcacat ctggaagatt
    20221 ttaatatagt tcctcccctg tgtataatat ctccaacaga agataagttc atttcagtta
    20281 aatcttcttc tagtaatccc ttatatcctc tattgattcc atatactttg catccataat
    20341 atattgctga tcttacaacc gctctaatcg cagcattcat tcctggagca tctcctccac
    20401 ttgttagtaa tcctatagtt ttcatttttt acctccttgg attttatgtc aattttttat
    20461 tataatcatt gttattgtat tctaatggac tttttttgtc cctatatcac tttttaatcc
    20521 catcaagact aaaaaaatta aatgtcctta aatgtccatt ttgtgatatt atatcacaaa
    20581 acggacaata tttttcatat tattataata tatttagatt tttatataaa aaatcaagct
    20641 tttactttta tgttatcttt aggaagtaac tcttctaagt tatttataaa ttcatcacat
    20701 atacaagtca atgccccggt cattttatat gctttacgtt taccatttat attttcatcc
    20761 atagggtata agtatatact gtcattacct ggatattgtt tggctatttc tacaatatta
    20821 ttagttgtat cagtatcaga catactatct attttcaaat acaatttttt accactttct
    20881 ggcttaatat tttctacatt tctagttctt cctgaattgt agtttctatc tgcaaagtca
    20941 gtatcatcat ttatatcttt tatctctcta gctataagtt ttgcattttc gccttctttt
    21001 atacttaatg ttccttttac atatattata ttatcttcat tcaaaatgac attatacttt
    21061 tgtaataatt gaggaaaaac tattatttct atagcaccat acaaatcttc taattcaata
    21121 aatgccataa tttcatttcg ttttgttgtt ttaatagttt tagttacaat cattccaccc
    21181 attataacat ctgtttcatt catttgtagg tatgactctt cttcctcttt taatgaattt
    21241 aattttccat tatccataga tgttttttct tgtagttctt tttcaaattg tgataaagga
    21301 tgtccactta catacattcc caagacttct ttttcaaggt taagtctctc tctttcttcg
    21361 tactcttgcc ttttaggcaa actgtatatt tgttgaaaat cactatcttc ctcactatct
    21421 ccaaaagcat caaataaaga aatttgacct tgaacatttt tctttctatc catagataca
    21481 ctttctaata aactttcata accagccatc agactagctc tattttcact tatattatca
    21541 aaagctccac attttattag actttctatt actctcttat ttgtatcttt ttggtctaat
    21601 cttttgacta aatctactaa atctacaaat aatccattag attctctttc agcgattata
    21661 ttgtttatta tatttacgcc aacatttttt acggctgcta gaccaaatct tatattgtcg
    21721 ccttcaactg aaaactttga aaaacttttg tttatatctg gaggtaatac atctatttct
    21781 agtgctttac attctcttat atactcaact accttatcag tatttcccat tacactggtt
    21841 atcaatgctg ccataaattc aactggataa tatgttttta gataagctgt ctcatatgct
    21901 aaaaccccat atgcagctgc atgtgattta ttaaatgcat atctagcgaa gtctatcata
    21961 tcatcaaata ttttattagc tatttcctct tctacaccat ttctgataca ccctgcaatt
    22021 tctatattac catcttcatc aaatttacca tgaataaaat attgtctttc ttcttccatc
    22081 acgtccatct ttttcttact catggctctt ctaactaggt cacttcgtcc gtaactataa
    22141 ccacctaaat ctctaacgac ctgcataacc tgctcttgat ataccaaaca accatatgta
    22201 acttccatta taggctttaa tttttcatgt agatatgtta catcttttgg gttgctttta
    22261 ttttttatat atgcaggtat agaatccatt ggacctggtc taaataggga tattcccgct
    22321 acaatatctt caaaattgtc tggttttagc tgtttcataa aacttctcat gccagcactc
    22381 tccaattgaa acacccctag tgtatttcct gatgaaagca tttcatatac tttcgggtcg
    22441 tcataatcca tctttgaaaa gtctattttt tctgtgtaat tttttataac tctatttttt
    22501 tctattaaat caagagtatc tcttataact gtaagagttc ttagcccaag aaaatccatc
    22561 tttaaaagcc caagttcttc aagtgttgtc atagtaaact gtgttgtgat tgcatcttga
    22621 tgtttgtaca aaggtacata ttcatctacg ggattttttg atataacaac tcctgctgca
    22681 tgagtagaag catgtcttag cattccctct atctgttttg atatatttat tatttctttt
    22741 gtttccgggt cttggtcata caattcttta agattaggat ttgtatctag ggccttatct
    22801 attgtcattc ctaaagcaaa tggtatttcc ttggctacct tgtcaacttt attgtagcct
    22861 atatccaata cccttccaac atctcttatt gcagcttttg cacccattgt tccaaaagtt
    22921 attatctggg ctacatggtc atcaccatat tttctcttta cataatctat aacttcttct
    22981 cttctctcat aacaaaaatc tatatctata tctggcatgg atatacgttc tggatttaaa
    23041 aaacgctcaa ataatagaga gtactttatt gggtctatat cagttatttt aagtgtatat
    23101 gctactatcg aaccagccgc actacctcta cctggtccta ctataatatt attttcttta
    23161 gaaaaattta taaaatccca aacaattaaa aaatactcta cataacccat tttttcaatt
    23221 acatctaatt cataatttaa tctctctagt atctcattac taggattatc atatctctct
    23281 tttaatccat taaaacacaa ctcccttaaa taagtttctg gtgtatatcc ttctggaaca
    23341 tcatacttag gaagatgtat agtattaaaa tcaaactcca cattacacat atcagctatt
    23401 ttcacagtat tgtcaatagc ctctaatgca tatggaaata attcttccat ttcttctctt
    23461 gattttaaat aaaactcatc actaccaaat ctcattctat ttgggtcatt taatgttttt
    23521 cccatttgaa tacacataag tacatcatgt attttcgaat cttctttatt tacatagtga
    23581 acatcattag tagcaactag tggtatacca gtctcttttg ataattttac taaaccagag
    23641 tttacttctt tttgctcagg taaattgtga tcttgaatct ccaaaaagaa attttcttct
    23701 ccaaatatgt ctctgtagtc aagagcaaat tgttttgctt tttcataatt tctattcatt
    23761 aaagcacgtg ctacatctcc tgcaaggcat gcagaaagtg ctataatccc tttgttatgt
    23821 tttttaagtt cttccatgtc aactctaggc ttatagtaaa aaccttctac gtatgaagtt
    23881 gaaactattt ttattaaatt tttatatcct tccatattct tagctaacag aactaaatgt
    23941 ccttgatatt tgtcatagtt tgggtcttta tctctcaatc cacgtgcagc tgtatagact
    24001 tcacacccta taattggctt tattccttct tttatagctg ttttgtagaa atctataaca
    24061 ccaaacatac aaccatggtc agttatagct attgagctca tgtttagttc cttagccctt
    24121 tttataagtt ttttcaccct cgaaaaccca tcaagtaaac tatactcagt atgtacatga
    24181 agatgagcaa aatctttgtt cattaaatca cctcctgctt tataatttta attttaccac
    24241 aaatatatgt cctaaaacaa aaacagagac ttttatctca aaataggaat taacttcaac
    24301 atataccatt atatgttata aattaatgct tattctgaga ttgtcccctc aatttattgc
    24361 tatgattttt ttttcaaatc tgttgcaatt tcttctattt ttctaagtct atgattgact
    24421 ccagattttc ctattggtgg ttctaacatc tctccaagtt ctttgagagt catatcctca
    24481 tactcgattc taatcttagc tatctcttgt aaattttctg gcaaactgct aattcctata
    24541 gtctcttgta tgagcttaat attttctact tgtcttactg ctgcatttac tgttttagaa
    24601 aggttagctg tctcacaatt tactatcctg tttacattat ttctcatttc ttttactatt
    24661 ttagtatttt gaagacttaa aagagcgtgg tgtcctccta taatactcaa caaatctgat
    24721 atttgttcac tctctttgat ataaacaacg tgattatttt ttctagccac aattttacta
    24781 ttaaaaccta aagagtttat aagttctttt agagaatctg caaactcctc attattagtt
    24841 acaaattcca tatgatagtt cttttctggg tcgcttatag aacctccacc aagaaaagct
    24901 cctcttatga aagctctctt acatccttca tgcttaatta agttctctga aattttgttt
    24961 atagtaaaaa atccttcttt atcttcaagt atacctaact tttttaataa catttctgaa
    25021 cccatttcgc ttgttaccat taatacataa ctgttatttc tctttagcat ttgattctta
    25081 tttactgaga ttgtagtatt gatattaaaa ttctttttta ataatttaaa tactttacgg
    25141 gctattgaat ttaactctgt tgttatcttt agatttagct tcttatatcc aacaatttgt
    25201 atacttcccc ctgatttaac tagagctgac aattcagcta tattacaaca ttcattccca
    25261 gatataactc ttgctagttc atttttggtt tcagttgaaa aagacatatc tatcacctat
    25321 taactaattt ttctttaacc ttttttttat ttcttgtaag gcaaccttta ttatctcctt
    25381 ttcatcatca tacctagcta agtctactac tctatctagg tggataaatt tagcatcaat
    25441 aaagccttcc tctttttgtg gaatagtatc catattcttt gcttgcatca aataccaaaa
    25501 aactgtttta tgaactgctc tattttcatc ccagttttct ttgaatgtat agtgtatttc
    25561 acctaaatat ttcaatatat ctgcttttac tccagtttct tcacttactt cacgtaatgc
    25621 tgcctcttgg ttattttccc cttcttctac ttttcccttg ggtaacaccc aatctccatt
    25681 gaacttcctt agtaaaagaa tcgtattgcc aaacaggact acaccaccag cactaacctc
    25741 ttctctcatc gatgttcact ccttaaaact aacataatga taaggatttc tacacaattt
    25801 tttaaaatcc ttttttacta acttttgttg taattatgat ttagggctaa ctcaataact
    25861 atgttagata tatactttgc atcatgtctt atataattat tttttatttc aattaaattc
    25921 ttctctacag tttttatacc catctctttt aatttatctt tttgcttttt atctaacaag
    25981 acttgctctg ctccatcttg tttatataag tcaagcattt cttctggcaa tatctcatta
    26041 tttgcgatta cataatctat taaattctca tcagtgtgtt ttactatagc attaacatgc
    26101 tctaatacat tgtacccttc tgtctcacct ggttgagtca ttatatttgc tatatatact
    26161 tttggagcta cagacgattt aatagcgtct acaatcccct ctacaagtaa attgggtatt
    26221 atacttgtat ataaacttcc aggacccata attataatgt cagcatcata aatagatgca
    26281 ataacatcct ttaatggttt tacatctttt ggatttaaaa aaattttatc aatagagctt
    26341 ttttgaattt ttgactcttc aggtatacta gattctccat ttattatatt gccattttct
    26401 aatttggcaa ctaaatttac atcttccaaa gttactggta aaactcttcc tgttatagca
    26461 aaaatttcac ttaatttata tacagctttt tcaaagtttc catacaaccc attcatagca
    26521 gccaaaaaca aatttccaaa actctgacct tttaaaagcc cttctgtaaa cctatattgc
    26581 ataacttcat tcattgttgg ctctatattt gcaagtgcta ataaacagtt tcttatgtct
    26641 cctggtggga gcattcctaa gtcttctctc aatacacctg aacctccacc atcatcagca
    26701 acagttacaa ttgcagttat attttgcgta gtgtgtttaa gacctcttaa aaataccgat
    26761 tgaccagtac ctccacctat cacaaccaca tttggttctc tattttcaac aatagacctt
    26821 tgaaatagtt ttactttttc attttttgct tttttatata taaataacga tacaattaat
    26881 gcaatccaac ctaaaattcc tacaataata agtaatttag ccatgtttgc ctccattatc
    26941 gcaacataga gtctctatgt ttctttacaa ctctatatcc cttattagat aaatcctccg
    27001 ctataagatt tgttatagta actgacctat gtcttccacc tgtgcatcca acaccaatta
    27061 ctagatgttg ttttccttcc tctatatatt gaggtactaa aaaatgaatc atatctaaaa
    27121 gtttcacata aaattcttca ctgattttag aattcataac ataatctcta acttctttat
    27181 catcaccagt tttagctctt aactcttcaa cataataggg atttggaaga aatcttacat
    27241 caaatactaa atctgcatca gcaagtatac catgtttaaa tccaaaagat actacagaaa
    27301 tagttaggtt tggattatct tcacctgaag aatatatttt ctttatttct tccttaaggt
    27361 ctttaggttt catgttagtt gtatcaatta tacatgtaga taactccttt aaaggttcca
    27421 ttatctttct ttccattttt ataccttctg gaatctgcat atcttttgcc aatggatgat
    27481 ttcttcttgt cattttatat ctctttaaca atacatcatc attacaatcc aaatatacca
    27541 tttcatattc ataattttct ttttctaaat aatttaagct ttcatgaagc gcttcaaaaa
    27601 actttctccc tcttatatct atccctagag caactttatc aatacttgaa tttggttgat
    27661 aacataattc tgcaaattta gttatcaaag caggaggtag attatctaca caataaaatc
    27721 ccatatcctc taaagctctc attgtctcac tttttccaga tcctgaaaga cctgtaacta
    27781 taacaaattt cattgctaac tcctcccttt tatcttatgt ttattatatt ataatgtttt
    27841 ctactaacga tatatccaga ttagagtcag atatagtctt catagctagt tcaaaatcac
    27901 caactctttc tggacaatgt gcatctgagc ctattataaa tttattttct agccctttta
    27961 ttttatttaa ttgatttaca ttcaaaaaag aatggctact atttatctca agtctagtat
    28021 ttgtcttttt tgctgtcttt gctacttctt ctatatacac atcgccttta tctcctggat
    28081 gagtaattat aaaaatatca ttattactta tcgcatttat tacagctttt gtattatatt
    28141 cttttgcttt ttcagtttta aaaatatagt tattacaatg atttaataag cttcttaatg
    28201 atgttggagt agaaccaaaa tgatatccag ccataatata atcaaaatct ctaataaatt
    28261 tatcatccat atctatattt cctttatcat ctaatatgtt acactccata cctaaaagta
    28321 tatttatatc agtgtactta tcatttaaat aatctacttc ttctctcatt ttgagaatat
    28381 cttttttctt tacaccatat gcaatatgtt tataactatg gtcagatatt cctattgttt
    28441 ttattccttt agaaatggct acctttacat tatcctcaat agtccctttg ccatgactat
    28501 ataatgtatg tgtatgataa tcagccagta ttttcatttg ttaatcctct ccaagtattt
    28561 tgacttcttc ttccaacata accccaaact tggcatatac agcacttttt ataacatata
    28621 ttaaatccaa aatatcttta gcacttgctt ctccttgatt gactacaaat ccacaatgct
    28681 tctcagatac ttgtgctcct cttaaagtaa gacctctcaa tccagtttct tctattaatt
    28741 tacctgcaaa atatcctgtt ggtctcttaa atgtacttcc tgcactagca aaatttaatg
    28801 gctgtttagt tattcttctc gtcgctaaat catccattaa actttttatt tcatcataat
    28861 ttccttcttg taattccaat tctgctgata aagctatata tccgtttttc gatattatac
    28921 tttttctata cccaaattcc atctgttcat ttgataattc aaatatattg ccttccatat
    28981 ccatcagtct tactgacttc actatgtcct tcatttcacc accatatgct ccagcattca
    29041 tggctaatgc tcctcccaat gtgccaggta ttcctgatgc aaactcaaac ccttttaatt
    29101 cttgcttttg gagagctttc cctaaaactg ataataaagc tcctgactga gcagtcatcc
    29161 tagtatcatt tatctcataa gaattgaaat tatcagctag ttctattacc actcctctta
    29221 ttccaccatc tttaattaaa atgtttgaac catttccaat tattaaatac ggaatagatt
    29281 cttcttttac caacttaagt acatttttta attgttcttc agttctaggt ctaactaata
    29341 tatctgctgg tcctcctacc ctaaatgaaa tatgtttttt cataggttca tcgactttta
    29401 tatcctcttt acttaatata tttaataaat ttatatatat atcttgatta ttcattgtat
    29461 ttcctcccaa attatactga actttagctg tcattattat ttaaattaca ttagtatata
    29521 gtattaacta tattcaataa tatatgattt tgcttatcat atggatttta tattttaagc
    29581 ttcttaatta caaactatat tcaataaata tataataaag taaaaaaaaa aaaataacaa
    29641 catataaaag aatataaata atttaaaaaa agcatcaata tcactgatat caatgcttta
    29701 aaaggcaatt taattcgtat tatttatcta actatttttg acatagcaaa gataataaat
    29761 ccctccaact actatggaac ctccaacgat atttccaagc gttacaaata ccaaattagt
    29821 tataaattga accatagtta tatttgctcc taatgccatt cccattggta taaaaaacat
    29881 gtttgcaaca ctatgttgga atccacataa tacaaatagc attattactg tccaacatga
    29941 agccaatttt gacattatat cttgagatgc tgtagccatc catacagcta aaacgactag
    30001 aatattacaa agtattgctt ttaaaaacat tgatgctata gttgaattaa ccttagcttc
    30061 tgccacagct atagcttttg tagctgcatc tcctgtcaat gtagaagaat aaaacacaag
    30121 tgcaactagc aaaattgaac ctactaaatt tgcaaaataa accagtcccc agtttcttaa
    30181 catttttcct aatgttattt ttttgtccat aagtgcaata gccattaagg tgtttccagt
    30241 gaataattct gctcctgcca ctactacaag cataagacct actggaaaga ccatagcact
    30301 taaaaagcta gctacccctg ggtctatctt gccaaaagtt tgactaacta tcatactccc
    30361 caatgcccca aaacctataa atgctcctcc aaataaacct aatagaattg cgttttgtgt
    30421 cgaaatattt gcttttttaa tgcctgcact tatagttgct tgtgcagttt ccccaggtgt
    30481 caagaatcct ttactcataa atccttcccc cttaaaaatt atactttccc ttgtcttttt
    30541 atggcaataa ttatataata acaatatgat atataataaa ttttattaac ataaaaaata
    30601 tactatatac ttatatatac ttgtctcata taattatact atttattata taacaacttt
    30661 gttaatttcg aaataattta tattgaattt gaaaaattta ccttttgatt atttatttta
    30721 ctttttaatt attgaggtat tatatataat agatatatgt ttgtgttatt atatataatt
    30781 acttatttta ataaatattt gaaggaggga attttatgtt tgatatatca tttttcgaaa
    30841 tgtcaatata tgaaatagca gttactacaa tatatataat taatttcatg gttatactaa
    30901 accttatctt tagagaaaaa agaaacataa atacaacttt aacatggctt cttatattag
    30961 tattgattcc tgctcttgga ttcatacttt atatagcttt tggcagaaat atttcaaaaa
    31021 acaatatgtt tagattgaaa gaaaaggatg ataagataat caaaagtaat atactagata
    31081 ctcaggttaa actccaatct acatctgaaa ttgattcaga tatacatcaa cataaggata
    31141 tgatttatgc attggctaat tcaaataatg ctcattatac caataataac gatgtgtgga
    31201 tttatgctga atctagtcaa ttttttaaca gtcttcttga agaacttaaa aaagctaaaa
    31261 aatatataaa catacaattt tacattttca aagatgacaa aatcggaact gaaataatag
    31321 acattcttat agacaaagct aaagaaggtg ttgaagtaag acttttattt gatgcagttg
    31381 gtggtagaac actaaaaaat agtacacttt ccagacttaa agaaagtggt gttaaagttg
    31441 gaagcttctt cccatcattc ttgaaaattg taaactttaa cttaaactat agaaatcacc
    31501 gaaaaattgt tgtcattgat ggtaaggtag gatttgtagg tggatataat gttggtgatg
    31561 aatatttagg tagaaatcca aaatttggtc tatggagaga tacacatact aagcttactg
    31621 gtgattgcgt aattgaccta aatatgagat tcatccttga ttggagatat acaactaaag
    31681 aagacttaga tttagaaaag tactttatag aagaagatac aaattctaat catccttctg
    31741 aaaatattgg gattcagata gtatcaagtg gtccagatat atcagaactt gatgagatta
    31801 aatatggtta ccttaaaatg attcagaaag ctagaaagta tatatacata cagagtcctt
    31861 atttaatact tgactcaact tttatagata ctttaaaaat agcttgttta tctggtgttg
    31921 atgtgagagt tatgattcct tctaaacctg accatccctt tgtatactgg gcatcatatt
    31981 catatgctgg agaactttta aagtttggag ctaaaatcta tacttatggt caaaatgcat
    32041 ttttacatgc taagacaata gttatagatg actctatatg ctctatagga acagctaata
    32101 tggatatcag aagttttgag cttaatttcg aagttaatgc atttatgtac tcttcaaaaa
    32161 aagcattgga acaaagaatt atatttgaaa atgatatttt aaattctaag gaaataacat
    32221 tagatatata taattctagg tctacttata taaaaatcaa ggaatcaatt tcaagactat
    32281 tatcagcagt tttataaatc ttttatttta taaaaatttt acattttggt ttatttttta
    32341 aagtttttta tatgtattat ttttttttta ttgaatttag ctcatttttt ttattttttt
    32401 taactattct gaattatttt atattataat agactagtat agtttttatt tttaataggt
    32461 aacttttttg cattgttttt ataaataaag aaattgttgt atattattct ttctttattg
    32521 ttttggtttt gttcacccac ataatgttgg ggtcaactca tggttaatta ttttatgaaa
    32581 aataataact ttaaaaagaa aagggggatt tgttatgtgc gattttattt cacacaacaa
    32641 gcaattattt gacgaactag atatatttat tgactctctt gcaacaaagg aaggtgcgtt
    32701 aatacaagtt ctacatgaag cccaaggtat atttggatat cttccaaaag aagttcaact
    32761 tcatgttgct agaaaacttg gagtagctcc tgcaaaggta tatggggttg ttacattcta
    32821 ttcttatttt actacagaac ctgtaggtaa gtataaaatc agtgtctgtc taggaactgt
    32881 atgttttgta aaaggtgctg acaaaatctt aagtgctttt gaaaaacagc ttggcataaa
    32941 agttggagaa actactagtg attttaaatt ttctttagaa ggtttaagat gtttgggggc
    33001 atgtggttta gctccagttg ttactgtaaa tggtaaagtt tatggtaaag tgaaacctga
    33061 ccaagtaagc gaaatattag atacttatag agaattagaa ttgaattgtt aagaggggtg
    33121 aataaataat gcgtaaagta aattcatttg atgaattaaa agttttagct gatgagctga
    33181 aacctaatct tagcttaaga aaaaattatt ctaaggaaaa tgtattaaga agagaattac
    33241 ttgtttgttg tgatactgga tgtacatctt caaacagtct agaaatagtt agtgaattag
    33301 aaaatgaaat aaagaaatca ggaatccaag ataaagttag tgttcgtttg acaggttgtt
    33361 ttggtttctg tgctcaaggt cctattgtaa aagtttatcc tgataacgtt ttctacgtaa
    33421 aagttgagcc atctgatgct gaaaagatag ttcaaagcca cttaattaga aatacagttg
    33481 tcgaggaatt attatatgag gaagaatctt taagtaaaaa agttgaagaa caagaagaaa
    33541 tgtctttcta caaaaaacag ttacgtatag ctttaaaaaa ttgtggtctt atagacccag
    33601 atagtataga agaatatatt gccaatgatg gttatttagc tctaggcaaa tgtttaactt
    33661 ctcttactcc tcaagaagtt attgcagagg taaaaacttc tggccttcgt ggtagaggtg
    33721 gtgcaggttt ccctactggc tctaaatggg aagctgcttc aaaaaatcca gctggtccaa
    33781 cagataaaaa gtttgttgta tgtaatgctg atgaaggtga cccaggtgca tttatggata
    33841 gatctgtact tgaaggtgac cctcatagtg tactagaagc tatggcaata tgtggatacg
    33901 ctataggttc tgatacagga tacatataca taagagcaga atatccaaaa tctatagaaa
    33961 gattaaaagt agccatagct caagctgaaa aatacggttt acttggcgaa aatatcttag
    34021 gcactggatt taactttaaa ttagaattaa aatatggtgc aggtgctttc gtttgtggtg
    34081 aaggtacagc gctaatgcat tcaattgaag gtagacgtgg tgaacctaga atgaaaactt
    34141 atagttcttc taagagtggt ctatggaaat ctcctacttg cttaaataac gttgagactt
    34201 ttgctaacat acctgcaatt atacttaagg gtggagattg gtttgccaac ttaggtactg
    34261 aagattctag tggtactaaa gtctttgctc ttggtggaaa agtagaaaat gtaggacttg
    34321 ttgaagttcc aatgggtact actttaagag atattgtatt tgaaattggt gggggaatcc
    34381 ctgaaggtaa gaaatttaag gctgttcaaa caggtggacc atctggcgga tgtataccaa
    34441 ctgaacattt agacactcct atagactttg gttcattaag ttctatcggt tcaatgatgg
    34501 gctctggtgg tatgcttgtt cttgatgaat ctgactgtat ggtagatata gccaagttct
    34561 tccttgagtt tactgttgaa gaatcttgtg gtaaatgtac accttgtcgt ataggtacta
    34621 caagattatt agaaatatta actaaaatta cagaaggtaa tggtactcta caagatttag
    34681 atgacctaga aaaccttgct gaaactatac aaactgcttc attatgtggt cttggtaaag
    34741 ctgctccaaa ccctgtttta agtactcttc aatatttcaa agatgagtat atagctcatg
    34801 ttgtagataa gaaatgtcct gctggtaaat gtcagaactt actttcttac tttataacag
    34861 atgactgtaa gggttgtaca aaatgttcta gagtgtgtcc tgctggttgt ataacaggtt
    34921 ctgttaagga acaacataca atagatactt ctaagtgtct aaaatgtggt gcttgtatag
    34981 ataattgtac atttaacgct ataatcaaga aataacttat ttggaggagg aataacaatg
    35041 agtttagtta atttaactat taatggcaaa cacgtttcag cacctagtgg aacttctatc
    35101 ttagatgctg cgaaattaat aaatataaaa atacacaacc tttgtcattt acatatgaat
    35161 gaaatagata agcttgacac ttgtgcttct tgtcgtgttt gtatggttga gacagagaga
    35221 ggattagttc cagcttgtgg aacagttata aaggaaggta tgaaagttca gactaatagt
    35281 gctaaagcat taaatgctcg tagaactatt gttgaattat tgttatcaga ccatccacaa
    35341 gattgttttg tctgtgaaaa aaatggagat tgtgaattac agactatagc tgctgattta
    35401 ggagtaagaa aaataagata tcaaggttct aaatcttttg caggtaaaga tacttctact
    35461 aaatctttag ttaaagacca ttctaagtgt atattatgta gaagatgtga gactgtatgt
    35521 aatgacatac aaacagtagg agcattatct ggagttaatc gtggatttaa tactttagtt
    35581 agtacattct ttaactctga tatggttgaa acagagtgta cattctgtgg tcaatgtata
    35641 tctgtctgtc caactggagc attaacagaa gtagataatg tacctaaact ttgggatgtt
    35701 ttaaataaaa aagaaaagac tatagtagtg caagttgctc ctgctgtaag agttgctatt
    35761 ggtgaagagt ttggattaga accagggtca atctctacag ggaaaatggt agctgcttta
    35821 aaagcacttg gatttgaaca tgtatttgat acaaactttg gtgcagattt tactataatg
    35881 gaagaagcta ctgaatttat agaaagaatc caaaaaggtg aaaatcttcc tatattaaca
    35941 agttgttgtc ctgcatgggt aaacttctta gagcacaatt atccagacaa gttaaactta
    36001 gcatctagct gtaagtctcc tcaaggtatg tttggttcta tagctaaaaa ctactatgca
    36061 cctaaaatat taggaatcaa tcctgaagaa ctttatgttg tatctgtaat gccttgtgta
    36121 gctaaaaaat atgaagcttc aagagaagaa ttaagtgaat ctggaatact agatgttgac
    36181 ctttctataa ctactagaga gttagctaag atgataaaag aagctgcaat cgatttacct
    36241 aatcttcaag accaagattt tgataatcct ctaggaaaat ctacaggtgc tgcatctata
    36301 tttggagcaa gtggtggagt tttagaagct gccctacgta cttcatatga gaagataact
    36361 aataagactt tagataatgt aaacttcact aatgttagag gtcttaaagg aattagggaa
    36421 gcaagtatag atgttgatgg aactacagtt aatgtgtgta ttgtaaatac acttaaaaac
    36481 gctagaaaga ttatggataa ggtcagaagt ggagaatgta aataccatat catagaagtt
    36541 atggcatgtc ctggtggatg tgttggaggt gctggtcaac cttatcacca tggtaatact
    36601 gaaatagttg atagacgtgc aaatgcgtta tatgaaatag atagaaataa ggctattcgt
    36661 aaatctcatg agaatcctga tttacaagct atttataaag acttctttgg agaaccaaat
    36721 agtgatgtag cccataaata ccttcatact cattactttg ataagagttg tgtctatgga
    36781 gagtgtccac aagaatgtgc ttgtgaagaa gctaagtagt cataacaaaa tataaaattt
    36841 attcttaaaa aaggattgtc ttaaaatact tttacgtaat ttaagacaat ccttattaat
    36901 ttcacaaatt aaattatatt tctaaataga cttattcttt aattaaccta tctattaatt
    36961 aaagaatacc tgccattctc ataagttgtt ttgcatttgt agttttacat cttccatctt
    37021 ttatcttata gtcaaaatga attttatcgt ctacatagta ctctgagaaa tgatagttta
    37081 caacttcaac atctccacta cctgaaaggt cacatagctc aaagtcatgt gttgtcacca
    37141 tacttataac ccagggtttt gataatttct ttactgcctc acttgctcca ataattctat
    37201 cagcagagtt agttccctta aaaatttcat ctactagaac caacattggc agttctttta
    37261 aactatattg aatcattgat tttattctaa gaatctcagc atagaaagtt gatattcctt
    37321 gacttacatc atcttgtatt ctcatagaag taaatatagc catacaggtc gcatcaaaac
    37381 tcttagcgca tactggagca cctgcatatg ccagcactaa gtttacaccg atacttctta
    37441 aaaatgttgt ctttccagac atatttgaac ctgtgataat acaagtctga gaatttaatt
    37501 gtatcgaatt tgctatgaca cttttttctg ctattaatgg gtggtatacc tcttcaactt
    37561 tcaatcttgg agtatcttca tattttatta ctggaaaaca tgtattttcc tttacatgag
    37621 aaacaactgt taaacttatt agagcttcaa attctccaat agattcaaac caatctctaa
    37681 tttgatttcc atatatacct ttccatcgct ccaaagcttc tgcacaatga tagttccaca
    37741 tcaaaacacc acaggcaatt atatatagta tctgattata ccttaggttt acagcatttc
    37801 ctattgaatt taattgttta acacctcttg aaactccact tcccttagaa agtttatctt
    37861 gtaattcttt caaatatgca ctctcaaacg tctctttttc taaaacctca aacatttttt
    37921 catatacttg tatacttcta ctaaatgaaa ataatggagc aagagtttgc ataagtcttg
    37981 gatatccaaa accactaaac cctaactgga ttataaaaag taaaaaaaca ggtaaaacag
    38041 gtaaaaatcc taacatacaa aatataaaag ataagattgt tgcagttggt aaaccccaag
    38101 taaaaatatg catccatttt ggtatataca cattcttatt ttctccatat tctataaacg
    38161 attctatact actatctgaa ttgttttttt gctctttacc aattatatta ctgagtgttt
    38221 gaatatgaat agaaaaatca tcttttgata aaagttcttt tatagctctc tgtctttcta
    38281 agattacatt ctcatctgga ttttcattcc acaaatattt ggctaaaaaa tttttcccat
    38341 aagatgtatt agctacacag atatattgat acaatgatgc tcttccaaat aagtctaaat
    38401 cttttgcttg cgaattttca tcttttaagt attctttacc atctatttta aattccttcc
    38461 aaccatctcc aaatctctta atatacttat ttaatacttc gctcttactt ttaaaatatg
    38521 tttcttcttc ttttacttta ctatgaataa ctaagagtgc tataaatatt attattgata
    38581 aaactccaac aaaaatacct actatatttt tattgtaaaa tccaatagca aaccctgcta
    38641 tcactatcaa aaaagatatt aatcttgctg tacttatgtt atttgacttt ttacttaaga
    38701 gcaattcttt ttcagtacta ctttctaaaa gtttactaaa atattctatt cccataaaaa
    38761 attccaactt tcttgttata taatgaaact caaatataaa attaatctag tattattata
    38821 atctaacact gtactttaaa ttatccttat ataatatatc ttattaataa acattatata
    38881 tatacaactt gattttaatt tataaggtgt aggacataat cctaatcaat atttaattaa
    38941 atgatgtgta gttcactatt attcagtact acttagtatc gattaatttt gataattttt
    39001 tagtaaattc ttgagctgca tcgtatccca ttcctctttg tctaaaattc attgctgcta
    39061 cttctaatat catagcagta tttcttccag gtttaacagg tacaactaat ttctctacat
    39121 taacaccaag tatttcttca tattctttat ccagtcccag tctatcataa tacttagttt
    39181 catcccaagc ttctaaatga actactaaat ctatcatttt agaatttttg attgccccta
    39241 ctccatataa acttctaaca tctattattc ctattcctct tatctcaaga aaatgtctta
    39301 ttagttcagg tgactgaccc acaagcatac tttcatctaa ttttcttatt tctacagcat
    39361 catctgcaac taatctatta cccctttgaa tcaattctaa tgctgtttcc gactttccta
    39421 tactactttc accttttatc agtacaccta taccataaat atctactagc accccgtgaa
    39481 ttgttgtgtg tggtgctaac ttattatcca aatagtttga cagtctattt ataagtctag
    39541 tggtatttct atttgtgctc aaaagtattc ttttatattt tttagccttt tcaattacat
    39601 ctggcttgat ttccaagtct ctagaaatta ttaacgctgg tatttcatat gagaaaaatc
    39661 tatctagtac ttcttcccga atatgactat ccattaatcc aaaaaaatta tattctgtct
    39721 ttccaactat ttgtattctt tcatatgcaa aataatcaaa atatcctgca aactgtaatc
    39781 ctggtctatt tatatcttga gagtagacat aataatctac atcatcaggc atgtatacta
    39841 cttttaactt caactctttt attatctctc ttattgatac tttattgcta gtttccatta
    39901 attttcttcc tttctaaaaa aattataaac attatctgca atgcttttat tcattccatc
    39961 tacttctaaa agttcttcca tagtagcttt ttttatagca tctacatctt taaagtgatt
    40021 taataatgat ttctttcttt tttcacctat tccttgtata tcatctaaga tagattttgt
    40081 caaagcttta tttcttagac ttctatgata tgttattgca taattatgaa cttcttcttg
    40141 tatactagca ataaatctat ataaattagt tgttttatct agttctattt ctttttcttt
    40201 gcatatcaat cctttagttc tatgcttatc atctttgtac attccccaaa gaggtatatc
    40261 tacatcattg agttctagta ctttttttac tgcactaact tgtccttttc caccatccaa
    40321 caatatcaag tcaggtaaat ttccatgttt taatcttcta tctacaattt cagccataga
    40381 atcataatca ttaggtccaa taactgtctt tattttatat ctcctatatt ccttcttatc
    40441 ttttttagca ttcgtataca ctaccataga accaatcgaa tctacacctt gtatatttga
    40501 tatatcataa gcctctattc ttattggcaa cttttctaga tttaatattt gctttaattc
    40561 ttccaatgct ccaatacttt tttcatattt tcttttattc atatcagaaa atttttcaag
    40621 atattctaca gcatttttcc taaccatttc aactaagctt ttcttctctc ccttttgagg
    40681 aactcttatt gttacttttt gccccttttt agatgacagc cattcttcta atatagaact
    40741 atcttctatc tcatcttcta taattaattc tttaggtata tactcttgtt cattataaaa
    40801 ttgttttaca aatgaactta atatagaagc tcttggacta tccattaccc cttctaatat
    40861 aaaatgttcc ctacctacaa tcttaccatt tcttataaaa aatacctgga cacaagcttc
    40921 attatgagct cttgccattg caaccacatc ttggtttaag tcacttacag tagcatctat
    40981 tttttgtttc tgtatcatct cttcaaggct ctttatctta tccctatata cagcagcctc
    41041 ttcaaatcta aagttcatag aactctcatt cattttttcc tttaaaagtt ccatcaattt
    41101 ttcttcttta ccagataaac acattataat ctcttctatc atttttccat actcttcttt
    41161 agaaacattt cctgtacaag gtcctaaaca tttatttatg tgtagattta aacaaggtct
    41221 tgtcttattc tttattgctt tatctatatc tattttacag cttcttattg gatacgtact
    41281 acttataagc tccaaggtat cattcacagc agttatattg gtatagggcc caaaatactt
    41341 tgccttatct ttaagaactc ttctaacttt taagattctt ggataatctt cattcgtagt
    41401 tacttttata tatggataag ttttatcatc tctaagcact acattatact ttggtctgta
    41461 tctttttatt aaattacatt caagtattaa tgcctctaac tctgaatccg ttataatata
    41521 ctcaaactta tatatattct taaccataga ttttacttta gatgtatggt tttttgaaga
    41581 ttgaaaatac tgccttaccc tattttttag agatatggct tttcccacat atattatatg
    41641 gtcgtatttg tctttcatta aatatactcc gggctcagaa ggtaattttt ttaaatgctc
    41701 ttgtatatca aacatctcgc cctccaaaac attaaatttt atactaaaat tataccctaa
    41761 aatatgaatt ttaaaaagtt atacaatttc cagtgcttta aacaagttaa agcccatatt
    41821 cccttctata attgatttga aaacaatttt aaccatgaag agtaatatgg actttacttt
    41881 gtattactat ttacaactta tatttgacta atttacttat aacaaaacag tttatcgtat
    41941 atctgctcta aaatttttca caatttatat aacttaagaa aaatatttct ttaagaattg
    42001 acctgtataa gaaccatcaa ctttagatac ttcttttggt gttccagttg caactatagt
    42061 tccaccctta tctccgcctt ctggtcctaa gtctattaca taatcacaag tctttataac
    42121 atctaaatta tgttctatga ctataattgt atttcctgta tctgctagtc tttgtaatac
    42181 ttggattagc ttgtctacat ctgccatatg aagtccagta gtaggttcat ctaatatata
    42241 caaagtcttt cctgttggtc ttttactaag ttcagcagct aattttatac gttgtgcttc
    42301 tcctcctgat aattgagttg aaggctgtcc taatttaata tatgaaagtc ctacatccat
    42361 taaagtttct aattttcttt ttatatttgg tatattttcg aaaaactcaa cagcttcttc
    42421 cacattcata tctaatatat cagatatagt tttatctttg tattttactt gcaatgtttc
    42481 tctattgtat ctttcacctt tacaaatttc acaaggaaca tatacatctg gtaagaaatg
    42541 catttctatt tttattattc catcaccctt acaagcttca catctaccac cttttacatt
    42601 aaaactaaat ctaccttttt tataacctct tgctttagct tcattagtag atgcaaaaat
    42661 atctcttata aaatcaaata cacctgtata agtagcagga tttgaacgag gtgttcttcc
    42721 aataggactt tggtctatat ttataacttt atctatactt tcaattcctt ttatctcctt
    42781 atgcttacca gctctttgct taagtctatt cactttactt gcaacacctt tgtaaagtat
    42841 atcgtttatt aatgtacttt ttccagaacc tgaaacacct gttatgcatg taaacttacc
    42901 taatgggaac tttacatcaa tatttttcag attattttct gatgctttaa ctatttctat
    42961 aaaacttcca tttccttctc tagtagtctc aggaagcaat atttgttttt taccacttaa
    43021 atattgaccc gttattgagt tctcattttc aattatttca tctaaagtac cctgtgcaac
    43081 tatttcacca ccatgtatac ctgcacctgg accaatgtct ataacataat cagcttctct
    43141 cattgtgtct tcatcatgct ctacaacgat taaggtattt cctaaatctg ttagatgtct
    43201 aagagtagtt ataagcctat cattatctct ttggtgaagc cctatacttg gctcatcaag
    43261 tacatataaa actccaacca atgcagaacc tatttgagta gctaatctta tacgttgcgc
    43321 ttctcctcct gataaagttc cagcttttct tgataaattt aaataatcaa gacctacatc
    43381 tcttaagaac atagctcttc cttttatctc ttttataatc tcatgagcta taaatctctg
    43441 tttttctgta agatttatat tttccataaa gtcaatcaat tcatttacag ataagtttgt
    43501 aacttccatt atattttttc catcaactaa aacagataaa acttcctttt taagtctcat
    43561 ccctttacac tttggacatg gtctctctgc catgtattct tcaatcttat ctctcatgta
    43621 atctgaatta gtttctctat atcttctctc taagtttact attacacctt caaagtatga
    43681 tttataattt ctagttcctc caaattttga ctcataagta aactctacaa ttatattatc
    43741 tttaccataa agtaattcct ccacaaaatc atctggtaaa tctttaaacg gtgttgtcaa
    43801 agatacatta aaatgctctg ctaaactttt tatcatttta ctgtaataag tgtcatcatt
    43861 aacacctgtt gaaccccatg ctgccactgc accttgtttt attgataaat ctttgtttgg
    43921 tactactaat tctgggtcaa cttctttact ttccccaaga ccattacaaa catcacaagc
    43981 accaaaggga gcattaaatg aaaacattct tggagataat tcttctatgc caattccatg
    44041 ttctgggcat gcaaatttag ttgaaaaaag aatttcttct ccatctatta tttgggctat
    44101 tacaagacca tcagatagct taactgcagt ttcaattgaa tctgctagtc ttgattctat
    44161 tccatcttta attactattc tgtccactac aacttctata ttatgttttt gatttttatt
    44221 taagattata tcatcactaa cttcatagtt ttcaccatta actctaactc ttacaaatcc
    44281 ttcttttttg atattatcaa agactttttt atgtgtacct ttttgtcctc taacaattgg
    44341 tgaaagaatt tgtaatttcg ttctatctgg aaaatctagc attttatcaa ctatttcttg
    44401 aatagtcatc tgacttattt tttcaccaca tgtagggcaa tacacatctc ctactcttgc
    44461 aaataatagt ctcaaataat catatatttc tgttactgtt ccaaccgtag aacgtgggtt
    44521 ttttgaggta gtcttctggt caattgagat agctggtgat aaaccctcta tatattctac
    44581 atttggcttt tccatctgac ctaaaaattg tcttgcataa gcagatagac tttctacata
    44641 tcttctctgt ccttctgcat atattgtatc aaatgccaaa gaagacttcc cagaccctga
    44701 caaacctgta aaaacaataa atttatctct tggtaattct aaatctatat tttttaaatt
    44761 atgttctttt gctcctctta ttataatttt atcttccata atgttgtttt tacctttcta
    44821 tttttccaat ttttcttcta attgtttcac tttatctcta agttctgctg ctctttcaaa
    44881 ttgtaagttt tgagcagctt ccatcatctc tgattttaat ttatctatat tagctcttat
    44941 ttcgtcttta tcatctgtat cagatattcc atatacaact tcttcctctg caaccttagt
    45001 agcttctata ctatctctta tatttttctg tatagtttta ggaatgatat tgtgctcttc
    45061 attatataaa ttttgtatat ctcttcttct ctttgtttca tcaatagcat tttgcattga
    45121 gtcagttatc ctgtctgcat acataattac tcttccattt tcatttctag ctgcacgtcc
    45181 aatagtctgt attaaagctg tttcggaacg taagaaacct tctttgtctg catctaaaat
    45241 tgctataagt gaaacttctg gtatatccaa tccttctcta agtaagttta ttcctacaag
    45301 gacatcaaac ttccctaatc ttaaatctct tattatttct gttctttcta atgtaactat
    45361 atctgagtgt aaatatttaa cttttatccc tatttcttta agatagttag tcaagtcctc
    45421 actcattttt ttagttaaag tggttataag cactctttca tttttttcta tagttttagt
    45481 tatttctcct accaaatcat ctatttgatt atttataggt cttacttcta caattgggtc
    45541 taaaaggcca gttggtctta ttatctgttc tgctattgtc tctgagtgtt gaatttcata
    45601 aggccctggt gtagcactta caaacaacat ttgatttata tttccttcaa attcttgaaa
    45661 atttaatggt ctattgtcaa gtgcagaagg taatctaaaa ccattctcta taagtgatgt
    45721 ttttctagac ctgtctcctg catacatacc tcttacttgt ggtatagtga catgtgcctc
    45781 atctacaatt atcaaataat catctgggaa gaaatccatt aaagtatatg gtctttctcc
    45841 ttctgacctt cctgtaatat gtctagaata gttctctatc ccctgacaaa atcctatttc
    45901 ctttaacatt tctatatcat acttagttct ttgttcaatt ctttgtgctt ctaatagcct
    45961 atcattttcc ttgaaaaatt taatttgttc ttgaagctcg ttttctattt ctacaattgc
    46021 cttttcaatt ctttctggcg ttgttacata gtgagatgct gggaatataa caacatgatt
    46081 tctagtacca acaatcttcc ctgttacata atcaatttct gttattctat ctacctcatc
    46141 accaaaaaat tctattctta ttgctttttc atcattacta gctgggaata tttctagtat
    46201 atctcctcta actctaaagg tacctcgtgt aaagtttatg tcatttcttt cgtattgtat
    46261 ctctattaac ctttttatta catcatctct gtctctttgc atacctggtc ttatagataa
    46321 cataagttct ttatagtctt ttgggtcacc aagtccatat atacaagata cagatgatat
    46381 tattatagta tctcttctct ctaaaataga tgctgtagca gaatgtcgaa gtttatctat
    46441 ttcatcattt atgcttgcat ctttttctat ataagtgtca ctgtgagcta catatgcttc
    46501 tggttgataa taatcatagt aacttacaaa gtattcaact gcattgtctg ggaaaaattc
    46561 tttaaactca ctgtaaagtt gtgctgctag agttttatta tgagccatta ttagggtagg
    46621 tttcttaact tgttgaatga tatttgccat tgtgaatgtt tttcctgaac ccgttacacc
    46681 taataatgtc gaaaatttct catttctatt tatagaatcc actattgatt taatagcttc
    46741 tggttggtca cctgtaggtt tgaagtctga ttttatttta aaatccatag tatcactcct
    46801 tttttcgaac attagttcct gacatgtatt attatatcat acctttataa aattgtttaa
    46861 gttattttaa atattttacc catttaaatt ttacttaaat ctaaaacata aaaaaagact
    46921 tctatctttg caatagaagt ctataattca tggaaaataa atactttatt caacttacat
    46981 aataaaatca aatgcttctt tttcaactcc atctaatttt aaattaaaca tttttaatat
    47041 agttgctgca tgtgctctca ggtctccttc ttctataacc acaccacctt taatatttgg
    47101 tccaaaagct ataaatggag gtctattacc tttagtaggt aaatgaccat gtgtcgcaac
    47161 agcaaacttg taatctttta tatctgaatc ttttataata cttccttcga aatcatttcc
    47221 aaatgaaatt ccttcaagac cttcaattac catttcaaaa tcaccttcaa gaccaaggtt
    47281 agatgcttcc tctttggtaa aaatattctc tatgaataat tcttctttaa attcttcaag
    47341 cagttctctt aattctgtta acctatctaa gttatttact attatttgag ctgatattcc
    47401 agaagaattt acataggcat caaaatcctt aacttctcca ttttcaactt ttataaatcc
    47461 atttgattta agcaagacat ttggatttat aactttatca actctaagat gaccatggtc
    47521 cccaagtatt ataaaatttg tatctttgta tgtacctgca tcctttgtag cctgaataat
    47581 atctcctaac catttatcat tcatttttaa tgctttatct acttcgtcat taaataagcc
    47641 ataattgtgt cgtgtatggt ccaatgtagc taaatgtatt agcattaaat ctggtttata
    47701 ttcctttatt atatctactg aacagtttac tccaaataaa tccatgttgg gttctaattt
    47761 ccaatcgata taatgacaat gtctattgta aataccgtcc attataacct tactggaact
    47821 tcgttcaaaa gtttctcttg ggtcatcttc tctactagga gcccatattt ctgcaatatt
    47881 ataatctata tttggatttg ctcccattac aggccataat acactagagg tagttagatt
    47941 attttctttt gctacatcta taatagtttt tgcttttatg tcctttgagt accagtacca
    48001 gtctttattt tctttatttg ggtcaaattt ttcattatga tatataccat gttttttagg
    48061 atatactcct gtaaccatac tagtatgaca cggatatgtc agagtgggat aaacacaatt
    48121 tatatttttt actatggagc agttttctag tatagattta aagtttggta gattttttac
    48181 aaattccaag tctttttcaa ataaagaatc tactgataat actataacct ttgtcattta
    48241 cattacctct tcatttatat attattgaat acttttaatc aacttacaag tctatataat
    48301 tatttatttg ttttatctat tactgcttgc attgcagaag ttcctttgct tactacatct
    48361 tttggatttg catttaaatc agtaagcccc tttttaatct catccattag cttatcagtt
    48421 gcttccttgt atccatttaa cattggaagt gcaacagcat attgtaattg gtcagttgca
    48481 accttatatt gaggtttttc tttatataat gtttgtaact tttctgagtt tgttgcatct
    48541 tcagttgttg gtaagtatcc tgttgatgaa ctaaactgaa cgattttatc tgtttgtgtc
    48601 atccattcta taaattctgc acttgcttct ttttctttat ctgttccacc ttcaagcata
    48661 actagattag ctccacctgt aggagttgcg tatttttgat tttttggtaa gaatgctgtt
    48721 gatatttcaa acttaccttc tgtttgttgc ataagtcctg ctaaatctgc tgttgatgta
    48781 aatatcatac ctactttacc atttacaaaa tcttgttttg ctacgtccca ggcattataa
    48841 tcttctccag gaggcatttt cattattcca gctttcatca tatcttgcca gaacttaact
    48901 ggtgcttgtc ctgcctcatt attaaatgct acttttttac cattagttat ttctcctcca
    48961 ctttgcatta ccatagcttc atagaaccaa atatctattg gtgtttcaaa accataagta
    49021 tcttctgatt tatttgtcat tttactagca taatccttaa gctcttccca tgattttgga
    49081 cctgaagggt caagacctgc tttagttgcc atatctttat ttatgtataa tattggtgta
    49141 cttctattaa atggcatacc aacaaactta tcctcataat atgaatttgt taaaagacca
    49201 gaaaagaatc tttcttgata tgttttatca aaatatttac tcatatctac taaagcacct
    49261 gctgatgcga atgtacctgt ttgagttatt tctaataatg ttacatctgg ttggtcttta
    49321 gatgttaagg ctgcctgtag ttttgttgca ttttcatagt aatctttctg ttttaacata
    49381 tttacttgta catccttatg ttcactatta aattggtcaa ccattttttg agcagtttct
    49441 ccattagttc cacctaaagg agcccagaaa tctatcttcg taatattgct atcagtcttt
    49501 tctcctttag atgcatttgc atcattagaa tttgaacacc caactaaaga acctaataat
    49561 aatgttattg ctaatcctgt tgctaatttt cttttaagct tcattttcat cctccaaatt
    49621 tagtctttaa ttttttattt tattcctgaa tacataaaag cttcttttac ttttttattc
    49681 gcaaatatat aaacaagaat tattggtaaa attagaatta tatttcctgc cattattaca
    49741 ttccatgcag taattccttc tgaagattta aggagcgcaa ctcctattgg taaagttctt
    49801 attgcatctg tatttgtcat tactaagggc cagaaataat tattccaatg gtatataaaa
    49861 ttaaataata taaatgttat tactgctggt tttgccatag gaaccattat tctaaacatt
    49921 atttttaagt cagaagcatt atctagttta gctgcttcaa taatttcatc tgaaatctgc
    49981 ataaaattct gtctaagcag aaatatccca aatgaagatg tcataaatgg aattataagt
    50041 ggaacataag tatttataaa tccaaactta ctcatcatca tatagactgg tagaaaagtt
    50101 acttgtggtg gaatcataag tcctacaagc aaaagcccaa atagcatttt ttcaccttta
    50161 aatttaatct tagaaaatgc atatgctgct ggaaccataa ctaaaaattg tacaattaaa
    50221 acacttcctg ttacaaatac actgtttagc aaatatctaa aaaatggacc tgaatgccat
    50281 gctgtactat aattttctaa cactatatca tttggtataa tagtgggcgg taattgcatc
    50341 atttcttgtg gatttttaaa ggatgtagat agcatccata taaaagggaa tataaatatt
    50401 gcagataaaa gtaatagaat taatatttct attgattttg atgctatttt ttttatatca
    50461 actttgtctt ttttgatagg ttgtataata tccattgtct cctccttttg gataaacctt
    50521 ataatatcta ctttttcttt attgataatg aactttcttt gataagagtc taaagttagc
    50581 atatgtagca atcataacta tagctaacaa aaacatactc gctgcactcg cttgccctat
    50641 gtcatagtat ataaatccag actcatatat ataataagat aacatgttag ttgaacccac
    50701 tggcccacct tgtgtcatta tacttatctc atcaaatact tgaaaagatg cagttgttgt
    50761 tgttatcata agaaaaaata ttgttggtga taatagtggc aatgtcactt taaagaaatt
    50821 cgttattttg tttgcattat ctaatttaga tgcttcatat atatagtttg gtatggattt
    50881 aagacctgat aacactatta agatattata tccaagagtc ttccatattc ctattagaat
    50941 tagtgacatt aaagctgaac tttcacttga aagccacttt gatgttggta aatgtaatgt
    51001 cgatagtatc cagtttaaaa agccatattg tggctccata atccaaagcc acaatacagc
    51061 tacagatact agtgaaatta catgtggtgt aaagattata ctttgcgtta aattgtgtat
    51121 tatagaattt ttatttagcc aaacagcaag tactatggct agtgatatag atatagtcac
    51181 cataaaaaaa gtataaattg cagtgtttgt tatagtttgt ataaactctg gattctttaa
    51241 aagttctgta taattgttta agcctacatt ttcaaaggtt gaactaagaa gactaccaga
    51301 tttgaagctt agagatatcg tcttaattat tggatagact ataaacaata aagttcctat
    51361 aatagcaggt gttatatata aatatgcttt attaaattgc tttttcataa atatctcctt
    51421 taattttaga atacatactt ttacatactt ttacatcttc tattctttct ccatttttat
    51481 caaaataata taaatctttt tctaatacac ttattcttaa agttcttcca atatcaaata
    51541 tatcattttc tgttttgact cttatctctc tattaagaac agataaacaa tatatagttt
    51601 catttcccaa cacttcttta gttacaactt ttccaaatag actaaataca tcatcatttt
    51661 ttccatctat gtttatactc tctagtgttg ctttttctgg tctgaatcca aatttaatat
    51721 cattttttat atctagtatg ttcatacaag gactccctat aaattgagct acaaataaat
    51781 ttttaggatt ttgatatatc ttctttggag aacctatttg cattatcttt cctttgttca
    51841 ttataactat cttatctgcc attgacattg cctcaacctg gtcatgagtt acataaacaa
    51901 atgtagactt tagtttttga tgtaattgta ttaattctgt tctcatttga tttcttaatt
    51961 tagcatctaa atttgacaat ggttcatcca ttaaaaatac ctttggattt ttaaccatag
    52021 ctctagcaag tgccactctt tgtctttgac ctccagataa gttgcctggt ttcacattta
    52081 aatattctct caatcctact acatcaataa cttctgttat aagtttttct cttttttctt
    52141 tttctacttt tttgttttta agaccaaatt ctatgttttc tctaacagtc atatgtggat
    52201 ataatgcata attttgaaat accatagcta tatccctttt actagcatcc gtttttgtaa
    52261 catcattttc ttcaatcttc aacctacctg aagttatatc ttcaagacct gcaatcattc
    52321 ttaacgtagt agatttacca catccacttg ggcctaccaa tactgtaaaa gaaccatctt
    52381 ctatagtaag atttaaattt tctataactg tatttttttt attataagat tttgttacat
    52441 tttctagtct tatatctgcc atttttatcc tcccaaaata tttaatttaa ttctacgatt
    52501 tacttataga ttaataatac tcttaatttg taaaggatat attaagacaa agtgaatata
    52561 tggtaaactt attaaaataa aggttaaatt ataaacattt tttgttaaat atactgaggt
    52621 taagatgata tacagcttat gttagctata attttctata tttttcatat tcattgtttg
    52681 ctatcacaat gtaattttaa tttatgaaga gtcatataaa actatttatt ttttatataa
    52741 tttgatttga aagtaaaaaa gacctctatg ggggatagag gtctttaagt gggggagatt
    52801 gagtaattta tttttgctat attaagtttt acaattatat tatgtcccaa atttacaagg
    52861 tttaaacata aaaaataaaa attttttaat ttttataaat ttacc
//
LOCUS       DAJMZY010000016        52794 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.016, whole genome shotgun sequence.
ACCESSION   DAJMZY010000016 DAJMZY010000000
VERSION     DAJMZY010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 52794)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52794)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52794
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.016"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            complement(121..894)
                     /locus_tag="OE968_000891"
     CDS             complement(121..894)
                     /locus_tag="OE968_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SigB/SigF/SigG family RNA polymerase sigma
                     factor"
                     /protein_id="HCP7218204.1"
                     /translation="MKNVANATHYLNMDTKELFNLYNKNKNVDIRNILIERHLYLARL
                     LAKKYINKGVDFEDIYQVASLALIYAIDRYDVEKGFEFSSFATPTIVGEIKKYFRDKV
                     WTLRVPRRIQELSKKISDAKIKLEQENKKHPKVKDIADYIGVSEEDVLEAMEASYGYQ
                     PMSLDSSSNDDSEDKDITLIDKIGKEEGNFGSIEYEDFINKFIETLNELEVKIFKDRF
                     FFDKTQSSIAKELGISQMTVSRLEKKVVEKLKKEYEKNL"
     gene            complement(894..1280)
                     /locus_tag="OE968_000892"
     CDS             complement(894..1280)
                     /locus_tag="OE968_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HCP7218205.1"
                     /translation="MEITTNPDYVSIIRLTASGIANKMGFPIDDIEDIKVAVSEACTN
                     AIKHSKDDVFNIVFNILDNAINIEIQDNGKGYDVSSISTPDLENPKESGLGLFIIKTL
                     MDDVDIESEHNQGTKIKMTKYLGVDI"
     gene            complement(1305..1622)
                     /locus_tag="OE968_000893"
     CDS             complement(1305..1622)
                     /locus_tag="OE968_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="STAS domain-containing protein"
                     /protein_id="HCP7218206.1"
                     /translation="MSMNIDSNLDSQNKFWNVCLDGELDVSTADKLKEHLHALIEKNM
                     LDVKINLKDLDYIDSTGLGAMIGVLKKLKINEKEIYIVNPKSNVRKIFTITGLDKIFK
                     VEG"
     gene            complement(1634..1894)
                     /locus_tag="OE968_000894"
     CDS             complement(1634..1894)
                     /locus_tag="OE968_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HCP7218207.1"
                     /translation="MNAWGWQIGAVLVGSSALIVAIYLAKTLNSINKVVEKAYKIVDY
                     NERHIQDIVENASSISKGIDDIVYVINKILSIGNIFKIIKRK"
     gene            complement(1894..2190)
                     /locus_tag="OE968_000895"
     CDS             complement(1894..2190)
                     /locus_tag="OE968_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HCP7218208.1"
                     /translation="MCNKRSCKKGGFLLLGAILGFIFGMFFAPKKGSELRKETKEKFN
                     DVKENPKEVLHETFNDVKERIINLVDDDNNEEDIKISEEDIVISKSFDDEGDVN"
     gene            complement(2259..4685)
                     /gene="gyrA"
                     /locus_tag="OE968_000896"
     CDS             complement(2259..4685)
                     /gene="gyrA"
                     /locus_tag="OE968_000896"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HCP7218209.1"
                     /translation="MEENNKILPIEIAEEMKKSYIDYSMSVIAGRALPDVRDGLKPVH
                     RRILYSMSELNLTPDKPYRKSARIVGDVLGKYHPHGDTAVYYAMVRMAQDFSTRALLV
                     DGHGNFGSVDGDSPAAMRYTEAKMSKLSLELLRDIEKETVDFKPNFDESLKEPSVLPA
                     RYPNLLVNGSNGIAVGMATSIPPHNLAEVIDATVYLIDNPECSVDDLIKFVQGPDFPT
                     AAIIMGKESIAEAYRTGRGKVKVRSRAFIEELPKGKQQIIVTEIPYQVNKAKLVERIA
                     ELVKEKRIEGISDLRDESNRNGMRIVIELKRDANANIVLNNLYKHSQMEDTFSIIMLA
                     LVDGQPRVLNLKQILYHYIKHQEDVVTRRTKFELNKAEARAHILEGLKIALDNIDAVI
                     SLIRASKTGQEAKLGLIEKFKLTEIQAQAILDMRLQRLTGLERDKIEAEYEDLIKKIN
                     RLKEILADERLLLNVIKDEITIIKENYSDERRTEIRHAEGEIDMRDLISDEEIAITLT
                     HFGYIKRLPSDTYKSQKRGGRGISALTTREEDFVRHLVTTTTHSRLLFFTNKGRVFKL
                     NAYEIPEGKRQAKGTAIVNLLQLSADEKIATLIPIDGNDENEYLLLATKKGIVKKTKR
                     EEFKNINKSGLIAIGLRDDDELIGVELTDGKQEVLLVTKEGMSIRFDENDIRYMGRTA
                     MGVKGITLSKEDFVVSMNLCSKGTDVLVVSKNGFGKRTNIEEYRSQIRAGKGIKTYNI
                     SEKTGTIVGADMVNEDDEIMIINSDGVLIRIRVNEISLFGRVTSGVKLMKTNDEVNVV
                     SIAKINIEEE"
     gene            complement(4705..6606)
                     /gene="gyrB"
                     /locus_tag="OE968_000897"
     CDS             complement(4705..6606)
                     /gene="gyrB"
                     /locus_tag="OE968_000897"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003226808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HCP7218210.1"
                     /translation="MKQEYGASQIQVLEGLEAVRKRPGMYIGSTSPRGLHHLVYEVVD
                     NSIDEALQGYCSDIYVSINEDGSVLVKDNGRGIPVEIHPKTGKSTLETVLTNLHAGGK
                     FGGGGYKVSGGLHGVGVSVVNALSKWMVAEVYLNGKRYKQTYEKGLPTSKLEVVGESQ
                     DKGTMIQFMPDETIFDEIEFKYETLEYRLRELSFLNKGIKIVFEDKREGQEKRKEFHY
                     TGGLVEYIKYLNKSRTGIHDDIVYIDKKVDDCFVELAMQYTDGYTENIYSFANNINTH
                     EGGSHLSGFKAALTKTVNDYAKRNKFLKENDVNLLGEDIREGLTAVVSVKLPEPQFEG
                     QTKTKLGNSFMRGIVDSVTVDELGSFLEENPSTARIIVDKALRAQRAREAAKKARELT
                     RRKSVLESTSLPGKLADCAEKDPSKSEIFLVEGDSAGGSAKQGRDRNSQAILPLRGKI
                     LNVEKSRLDRILSSDEIKNMITAYGCGIGEDFDIDKARYHKIIIMTDADVDGAHIRTL
                     LLTFFFRYMRPLIDEGYVYAAQPPLYKVTKQKKEHYVYSDKELNILLDEIGRNGVELQ
                     RYKGLGEMNAEQLWETTMNPETRTLLQVTVEDAAIADEVFSMLMGDKVAPRKEFIEEN
                     ARFVRNLDI"
     gene            complement(6607..7722)
                     /gene="recF"
                     /locus_tag="OE968_000898"
     CDS             complement(6607..7722)
                     /gene="recF"
                     /locus_tag="OE968_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HCP7218211.1"
                     /translation="MKLKSLQLVNFRNYKKLHLEFNGKVNLLVGKNGQGKTNIVESIY
                     MLSFGKSFRTNKDKEMVRFNSENLYIGGSFSKYNKYSLIELIIGKDKKGIRINKVPLQ
                     KIQELLGNLNVVIFSPEDLRLVKEGPKERRAFIDKEISQIIPKYYKYLTNYNKTLSQR
                     SRVLKNIHVDEALLDVYDDTLAKYGSYIYILRRDFIKKIANISENMHMNLTNGVERLS
                     IRYKNQINITDEDTIDTVYNKFLAKLSSNRPNDIESKTTRYGIHKDDLNIFINDLDAR
                     LFGSQGQQRTASISLKLSEIELIKNEVEEYPVLILDDVFSELDEARQKLLVNNLSNVQ
                     MFITSAEVSHKKIFDEKNVTIFNIENGDVISIENGGN"
     gene            complement(7739..7945)
                     /gene="yaaA"
                     /locus_tag="OE968_000899"
     CDS             complement(7739..7945)
                     /gene="yaaA"
                     /locus_tag="OE968_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HCP7218212.1"
                     /translation="MTEITIESEYIKLDQFLKLAEIASTGGHAKFLIQEGLVTVNDEI
                     ELRRGKKIKSGDIVEIEGTKIKVL"
     gene            complement(8082..9188)
                     /locus_tag="OE968_000900"
     CDS             complement(8082..9188)
                     /locus_tag="OE968_000900"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HCP7218213.1"
                     /translation="MKIICNQKILANRIGIAQKAINGKTTIELLKGILISTEEGQLKL
                     TGYDAEIGIETYVQAEIIEKGDVVVDARLFGDIIRKLPDSFVEIETDSENNIYINCVN
                     SRFKIKGYAAKEFPKLPELNEEDLYSIPQEILKNMIKQTVFAISQDQTKPVLMGELLE
                     IVDRNLNLVAIDGYRLAVKSCSVDSLTENIKVIIPGKTLIDVNSLLSGEDNVKVGFNE
                     KNAIFIINDTKIITRLLEGDFIDYKKLLPREHNSRVKLNTKELLNSIERASLLSQSEK
                     NNLIKLSIRDKVMAITSNTEKGNVYEEVEIDLDGDYLDIAFNSRYFIEGLKNIDNEEI
                     FIEFTTNVNPCIIKPTDDVNYIYLLLPVRISSNI"
     gene            complement(9430..10752)
                     /gene="dnaA"
                     /locus_tag="OE968_000901"
     CDS             complement(9430..10752)
                     /gene="dnaA"
                     /locus_tag="OE968_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HCP7218214.1"
                     /translation="MMDIVSLWDKTLQLIKGDLTSVSFNTFFKNIVPLKIHLNDLILL
                     APSDFNKDILENRYLHLIEDAISQLSLKKYNIKFVLSEKEVADLNSDSTDLNYRVLYP
                     NLNPKYTFDTFVIGNSNRFAHAACVAVAESPAKAYNPLFLYGGVGLGKTHLMHAIGHH
                     IVSQKKDSKVVYVSSEKFTNELINSIKDDKNEEFRNKYRNVDVLLIDDIQFIAGKERT
                     QEEFFHTFNTLHEANKQIIISSDRPPKDIPTLEDRLRSRFEMGLITDIQAPDFETRIA
                     ILRKKAQLERIDVPNEVMSYIAKNIKSNIRELEGALTRVVAYSSLSNRVISFDLATEA
                     LKDIITTSKNEEINVLRIKEKVSSVFNLKMEDFNSKKRTRSIAYPRQIAMYLTRELTD
                     LSLPKIGEEFGGRDHTTVIHAHDKVSKDIEESEEIKTKIDKIISDLKG"
     gene            11408..11545
                     /gene="rpmH"
                     /locus_tag="OE968_000902"
     CDS             11408..11545
                     /gene="rpmH"
                     /locus_tag="OE968_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HCP7218215.1"
                     /translation="MSKRTYQPKKRQRSKEHGFRKRMKTSNGRNVLKRRRAKGRNRLT
                     H"
     gene            11623..11967
                     /gene="rnpA"
                     /locus_tag="OE968_000903"
     CDS             11623..11967
                     /gene="rnpA"
                     /locus_tag="OE968_000903"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HCP7218216.1"
                     /translation="MDFNRTKGLKKDSDFRKVYKHGKSFANKYLVIYILKNKSDYSRV
                     GISVSKKVGKAITRNRVRRLIKEAYRLNIDEKIKPGYDIVFIARVSSKDATFKDIDKS
                     IKNLVKRTDISI"
     gene            11999..12250
                     /gene="yidD"
                     /locus_tag="OE968_000904"
     CDS             11999..12250
                     /gene="yidD"
                     /locus_tag="OE968_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HCP7218217.1"
                     /translation="MNKIIYILKEISKHLSNLCIYLVRFYQKYISPLKGPTCRFYPTC
                     SQYSIEAFKKYGFVKGMYLTIRRLLKCHPFHPGGYDPLK"
     gene            12282..12989
                     /locus_tag="OE968_000905"
     CDS             12282..12989
                     /locus_tag="OE968_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HCP7218218.1"
                     /translation="MNIIGNFLGLILKVIFEFVNHYGISIILFTILVKIILLPLTIKQ
                     TKSTKAMQDIQPRIKEIQEKYKNKPEKQNEEIVKLYGEAKINPLSGCLPLLIQFPILI
                     GLFSVLREPVAHGVFANKAAFLAADNGFLWIKSLTSPDYVLAVFSGASAYVMQKVMTP
                     KDQLQGSMKVMTYVMAGMSFYWGFIFPAGLTLYWTVSNLFSIAQYYLIMNPLKAKLAA
                     NSKEEKVNEKKPKINKK"
     gene            12958..13587
                     /locus_tag="OE968_000906"
     CDS             12958..13587
                     /locus_tag="OE968_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HCP7218219.1"
                     /translation="MRKSLKLIKSKSKEEAISKAIAELNLKAEDIEVEILENPSKGFL
                     GFIGAKDGTYEIFVIEREVDVAKNFIEVMLKNANVDAKVNVSQKDNLIMVDIEGKEAA
                     SLIGRRGETLDSIQFLTGLALNKINKDSHTRVLVDIENYRSKREESLIRYANKVAREV
                     AKTRKTKKLDYMNPYERRIIHSALQNDKYVITYSEGTDPYRRLVIECKR"
     gene            13699..15078
                     /gene="mnmE"
                     /locus_tag="OE968_000907"
     CDS             13699..15078
                     /gene="mnmE"
                     /locus_tag="OE968_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HCP7218220.1"
                     /translation="MFIDDTIAAIATAPGEGGIGILRISGEKALKVAEEIFKSMSGKS
                     IEEYNKRTLIYGNIVDNENVIDEVLLAYMKGPNSYTGEDVIEINCHGGFISVKKILEL
                     ILSKDVRLAEAGEFTKRAFLNGRIDLSQAEAVIDVIKAKTDIAHEVAQNQLEGSLSKK
                     IRELRDKVTEILAHVEVAIDYPEEDIEHITYQTLKEKTDELKKDIKKLYDTAESGKIL
                     REGLKTVIVGKPNVGKSSLLNSILGENRAIVTDIPGTTRDVIEEFVNIKGIPLKIVDT
                     AGIRDTDDIVEKIGVEKSKESFTSADLIVMVLDASRKLSEEDIEILEKLKDKQTIVLL
                     NKNDLKQEIEEEKILKYVENNSIIKISALQQEGIEELQDKIESMVYKGSIKNNSSLVV
                     TNSRHKDALSKAYKSATDALIALEQSMPFDFVEVDLKNIWDYLGYINGDTVTEDLLDN
                     IFHNFCIGK"
     gene            15176..17068
                     /gene="mnmG"
                     /locus_tag="OE968_000908"
     CDS             15176..17068
                     /gene="mnmG"
                     /locus_tag="OE968_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012065747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HCP7218221.1"
                     /translation="MKFEAGKYDVIVVGAGHAGCEAALATARMGYKTLIITMSLDSIA
                     LMPCNPSIGGTGKGQLVKEIDALGGQMGLNIDKTYIQSRMLNTAKGPAVHSLRAQADK
                     FKYHEEMKKTLEDEPNLDIAMDEVVEILHEGNVVIGVGTKLGCSFKSKAVILATGVYL
                     NSKIYMGEVAFYEGPNALGYAKYLTDSLVELGLRMRRFKTGTPARVHRDSIDFSVMSL
                     QEGDEKVTPFSFMNENIEKKQEPCYLTRTTEETQKVILDNLKRSAMYSGVIESTGPRY
                     CPSIEDKVVRFSDKTSHQLFIEPEGLNTKEMYIQGISTSLPFEVQLDMYKTIKGLENC
                     KIMRPAYAIEYDCVDPTQLKISLEIKGVENLFSAGQFNGTSGYEEAAAQGLMAGINAV
                     RKIEGKEPFVLDRSEAYIGVLLDDLVTKGTNEPYRMMTSRAEYRLYLRQDNADMRLTQ
                     KGYDIGLVKKDRYERFLNKKAAVEKEFERLKNERVTPKEVNSLLEEKGATPIKVGISL
                     YEFLKRPEVTYELLEELGKGAGEDVSREVKEQCVIITKYEGYIEKQLKQIDQFKKLEN
                     KKLDEKINYSSIEGLRLEARQKLDDIKPISIGQASRISGVSPADISVLLIYLEQIRRT
                     RGGKGE"
     gene            17061..17780
                     /gene="rsmG"
                     /locus_tag="OE968_000909"
     CDS             17061..17780
                     /gene="rsmG"
                     /locus_tag="OE968_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HCP7218222.1"
                     /translation="MNNIELLKNGIEGFNIDTNDSMLEKFKIYREILVEWNKKMNLTG
                     IEDEKEVYIKHFLDSISAVKNGYIKNGMSIIDVGTGAGFPGIPLKICLDSLELTLLDS
                     LNKRINFLEEVSRVLELDNITFIHGRAEDFGKNEDYREKYDVATARAVAGLPILMEFC
                     VPFVKVGGYFICLKGPNANLELEESQKAIDVLGLEYIEKIDVELPEVDLNHNILVFKK
                     VMETPVKYPRKAGKPAKNPIK"
     gene            17943..18728
                     /gene="noc"
                     /locus_tag="OE968_000910"
     CDS             17943..18728
                     /gene="noc"
                     /locus_tag="OE968_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid occlusion protein"
                     /protein_id="HCP7218223.1"
                     /translation="MEDKRVMEIPIEDVVPNPYQPRKIFSQVSLEELSNSIKVYGIIQ
                     PITVRAKDGKYELIAGERRLRAAKLAELKTIPAIINNMNDESSAVLALLENLQREDLN
                     FIEEAIGYENLIKEHAFTQQQLAEKLGKNQSTVANKLRILKLPNDIKMKLIENNLTER
                     HARAFLKLPSEDLMQSVLDKVIKNELTVKKTEKLIQDVLEETKVQEEPDKKQNIKGAM
                     SIRIYINTIKQAFDAISNTGIDAKYNEIDKGDYMEVVVKIPKK"
     gene            18863..19636
                     /locus_tag="OE968_000911"
     CDS             18863..19636
                     /locus_tag="OE968_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HCP7218224.1"
                     /translation="MGKVIAVFNQKGGVGKTTTNVNLSASLGTLGKKILVLDLDPQGN
                     TTSGYGINKNEVENTIYEIMLDGLHIKEAIISTEFENVDVVPSATELSGAEIELTSKT
                     NREYILKNSIKAVIDEYDYIFLDCPPSLGMLTINCLTAVDSVLIPIQCEYYALEGVSQ
                     LMETIKLVKSRLNADIEIQGVVLSMFDGRANLSIQVVEEVKKYFKGSVYTTLIPRNVR
                     LAEAPSHGKPVIYYDKRCRGSVAYLELAEEFIDLEEEEW"
     gene            19638..20501
                     /locus_tag="OE968_000912"
     CDS             19638..20501
                     /locus_tag="OE968_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HCP7218225.1"
                     /translation="MENKSKRSNRLGRGLSALIPEIKGETSEKEIVNIDIDKIYPNEV
                     QPRKQFDEEKIKVLSDSIKNYGVLQPIVVKMDENNKYMIIAGERRFRASKLANKNQIP
                     AIIKDIDMKDIMEIALIENLQREDLNSIEEALAYKSLIEHYNVTQEEISEAVGKSRPH
                     ITNTLRLLNLGQDVIEMIDSGRITAGHGKALLRIADKDLQLQIAKKIEEEELSVREVE
                     NIAKKISENKQEEPKKSKPKDVFILDVEDKLRNIFGTKVNISKGKKKGKIEIEYYNDD
                     DLNSIVSMLLE"
     gene            20534..21676
                     /locus_tag="OE968_000913"
     CDS             20534..21676
                     /locus_tag="OE968_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HCP7218226.1"
                     /translation="MIYLDNAATTYPKPERVYNAVLDCMKNYCANPGRAGHKLAMRAA
                     REIYDTRENIAKLFNVSNPMNIVFTSNATDSLNLAIKGVLQEGDHVITTSMEHNSVIR
                     PIKALEKRGIENTVVKCDYEGFLDYEDLEKSIKNNTKLIVTTHASNVCGTLIDIKKVG
                     EIAKKHNILFLVDASQTAGVYDIDVNECNIDMLAMPGHKCLFGPQGTGILYVREGLNL
                     NILKEGGTGSKSEEIVQPELFPDKYESGTHNTPGIAGLNQGILFIFERGINNIRQHEE
                     ELCQYMIDKLEEVPDIKIYGPKDSKKRASVIALNIGDMDSGEVTFLLDSDYNIATRSG
                     IHCSPLAHTTLGTLKQGAVRFSIGYFNTKDEIDKAVEALKKISKNK"
     gene            complement(21810..22385)
                     /locus_tag="OE968_000914"
     CDS             complement(21810..22385)
                     /locus_tag="OE968_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GerMN domain-containing protein"
                     /protein_id="HCP7218227.1"
                     /translation="MKNKKIMLVLSILSISIFAVGCTNAQNGSDSSKKETKSNTNVEQ
                     PKEENNTEKEVPNNKAKPTPKEETKAQSATIYSFDVDKTDLIENKVDLNKIDENTLFE
                     ELQKLKVVPESAKLNSFTTKDIDGVKTGILDVSSDFTKSNLGSDAETLMLDSVARTYI
                     KNMNVEQIKITVDGSNYESGHIVLEEGDYLK"
     gene            22645..23937
                     /locus_tag="OE968_000915"
     CDS             22645..23937
                     /locus_tag="OE968_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HCP7218228.1"
                     /translation="MEILSLGEKIKKLRKEKNMTLKELAGDRITAAQISHIERDKSHT
                     SYELLEYLGDKLDVSVEYLLETKEMQSKKITDNLILQSEIYIKENELNKAEDQIKEVL
                     DICKRYDLMENYGRCNFLMANINLKKSNYNDAIENFEKALYFFIKNSDSENILKCYLN
                     IGKIYMQEDFYKGAISHFNFAEEILSESKFEDVNIHKELYSKMAYCYIKLDNPNMSLK
                     YIEKINEIDNRNDRKEDVDILVLKANNMLEIGKYEESRDYFKKALKILESEDNKTGLA
                     NVYLTICDVYRKIGETDRVLEYSQKVYDIKKNDEDEYMMSGLFKIIEAYIDKEDYDLA
                     RKYCKIALASSIKNKNKFNEYKALRFYANMYKNQNEVTLAIEYLIKCIKIVSDLGNNR
                     ILANLYIDLGQLYSNISKEKELEYYQKGVFMYKNLEIM"
     gene            24042..24644
                     /gene="yedF"
                     /locus_tag="OE968_000916"
     CDS             24042..24644
                     /gene="yedF"
                     /locus_tag="OE968_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase-like selenium metabolism
                     protein YedF"
                     /protein_id="HCP7218229.1"
                     /translation="MSIKIDARGLACPKPVINTKRELDNLEEGVVVTIVDNETAKENI
                     LKLAKSLSCEANIVDEKENFISIEIRKGKNILDKQNVVDNKESELDNTCIFISSDKMG
                     LGNDELGKVLIKGFIYTLTESKPYPKYVLLVNGGVKLSAENEETIENLKILENMGVEV
                     LSCGTCLDYYNLKDKLQVGTVTNMYTIVETLKNASNTISI"
     gene            24717..24980
                     /locus_tag="OE968_000917"
     CDS             24717..24980
                     /locus_tag="OE968_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3343 domain-containing protein"
                     /protein_id="HCP7218230.1"
                     /translation="MNQMYIVSFNSTHHAIRSEKLFGENSLKVMALPTPREITASCGI
                     SIKFSFEDMEKIKTILVENNVDIKGIYCISKLENGSKEVEKLD"
     gene            24995..25180
                     /locus_tag="OE968_000918"
     CDS             24995..25180
                     /locus_tag="OE968_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HCP7218231.1"
                     /translation="MPMDLKIGDIVELKKQHACGCKEFEIIRTGMDIKIKCTKCSRLI
                     MLDRETLEKRVKKLIKK"
     gene            25283..26479
                     /locus_tag="OE968_000919"
     CDS             25283..26479
                     /locus_tag="OE968_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HCP7218232.1"
                     /translation="MAVKYAKRMQGLQGSEIRELLKLTQQPQIISFAGGMPAPELFPV
                     EEMKKVSVAVLEENGRSAMQYTTTEGYEPLREKIAARMNDKNKTNVNKDDILVTSGSQ
                     QGLDFAGKVFIDEGDVILCESPSYIGAINAFKSYQPKFIDVPTDSDGMIMEELEKILE
                     TTDRIKMIYVIPDFQNPTGRTWPLERRKKFMEIVNKFEIPVIEDNPYGDLRFEGETLP
                     SLKSMDTKGLVIFLGTFSKIFCPGYRLGWTCASPEILSKFNFAKQGADLQASTISQME
                     VSKFMDMYDLDAHVDKIKAVYVKRRDVMLKTMEEEFPEGLVFTHPEGGLFTWVELPSN
                     LNAKELMPKCLDKNVAYVAGGGFFPNGGRENTFRLNYSNMPEEKIIEGIKNIAAVLKE
                     AMGVEA"
     gene            26693..26971
                     /locus_tag="OE968_000920"
     CDS             26693..26971
                     /locus_tag="OE968_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HCP7218233.1"
                     /translation="MRNYELVYVVKPNSDEEVREAILNKVKEVVATDGEIVKVDTWGT
                     KKLAYPIAKFTEGFYVLVNFKSAVDVPKEIDRNLKINENVIRHMIVVA"
     gene            27008..27442
                     /gene="ssb"
                     /locus_tag="OE968_000921"
     CDS             27008..27442
                     /gene="ssb"
                     /locus_tag="OE968_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HCP7218234.1"
                     /translation="MNQVVLVGRLTRDPELRYIPGTGTPVASFTIAIDRDYVKKDGSK
                     ETDFIPVEVMGKSAEFCANYITKGRLVALQGSIRVDNYQTQSGEKRTFTKVSTRSVQA
                     LDSKNKSENSYRESAPAFEPSFEPQGLDPQGFQAIDDDDIPF"
     gene            27461..27688
                     /locus_tag="OE968_000922"
     CDS             27461..27688
                     /locus_tag="OE968_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HCP7218235.1"
                     /translation="MMNKKRRKKKRVCQFCADKNAKIDYKSTQRLQKYITERGKILPR
                     RISGTCAKHQRELTVAIKRARNIALLPYTLD"
     gene            27831..28151
                     /locus_tag="OE968_000923"
     CDS             27831..28151
                     /locus_tag="OE968_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HCP7218236.1"
                     /translation="MKIDKGSEITRNIKIIEWMKTEILMSVSDLFNLLFKGVKPLDEA
                     IQDTLANIIMITYLLAKRLGISFRDVDYKVKEKIKIGIDEDHSVERWYGDLSNLKKHM
                     DNRE"
     gene            28159..29115
                     /locus_tag="OE968_000924"
     CDS             28159..29115
                     /locus_tag="OE968_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YybS family protein"
                     /protein_id="HCP7218237.1"
                     /translation="MNNKIRLSKAMSIIVLAIIIALVIAYIPMLGIFSMLAAVPYVII
                     GAITDRKYSLISILVTFCVLILFADISYALNICIMYSLPGIVIGKMLKRSFEQEDSNK
                     FEPIYGGTIIFVLSMLVYFFVLKTFLNVNLLDEVSKMISEIVNIQKNSFSATELKVFD
                     KMKPDEIVSYFTNMLPMMLFLQGLLSAFVTYYLSVFFIKRITKMNIRFPKFADFYLPG
                     NAILTTFLLYLLVLFIQIIGSKLYTELIMTNLQLVFNLMFVIQGIAVCIYFLKKWIRQ
                     GPNKIMFFSGIILCLFGFMGISFVGMVDSIIDFRKVRSYKST"
     gene            29126..31120
                     /locus_tag="OE968_000925"
     CDS             29126..31120
                     /locus_tag="OE968_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HCP7218238.1"
                     /translation="MSNKQTFKLNMPEINLYIIVIGISSIILLYYNLYVGCLFFCIFV
                     YMVFHNWRTTNIRRHEWTEYIQNLSLDIDETTKKAIINLPIPLCILEFDGNISWYNGK
                     FYDMIGQKDLLDKNIEDIVKNLNLRKVLNENKEMYTEINYKEKEYTIIYNVIKNDQEK
                     NPKYLMILYWIDKTEYLKVKQNYDDEKNAMMLIQVDGYDEVLKSAAEDKRALINVEVE
                     KILSALELNSNGALRRTSKDKFFLVMHKKELKKLEAEKFSILDTIRHIDYGNNLPVTI
                     SIGIGIDGDTLNENLKLATGALDLALGRGGDQAVVKTKDKFVFYGGKSKAVEKKTKVK
                     SRLIGHALREVIQQSDQVYIMGHKYPDMDAMGAAVGVYDICKSCNKTANIVLQSVNES
                     IEIFINKINENNYYKKLFIGKEEAIDNCTKNTLVVVVDTHRPNYTECEELLKLSEKVV
                     VIDHHRRGVEFINDAVLLFHEIYVSSTCEMVTELVQYMDEDVTINKLTAEGLLAGISL
                     DTKNFAFKTGVRTFEAASYLRKVGADTIEVKKFFNSDVKDFIIKAEIIQSTKIINNRI
                     CLAYSSTEIDSINVIIAQTADELLNIKEVEASFVLGEKDDTIFISARSLGQINVHVLM
                     EKLGGGGHIDIAGAQLKNVSLKEAYKMVNKIIEEYLEEEE"
     gene            31121..31570
                     /locus_tag="OE968_000926"
     CDS             31121..31570
                     /locus_tag="OE968_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HCP7218239.1"
                     /translation="MKVILLKDVKGTGKKGEMKEVSDGYARNFLFPKKMAVQADSVAI
                     KELNEKNKSKEIKAQKEYEEAVLLGKQMEEINIEIYSKAGEGGRLFGSITSKEIAEQL
                     KKQKDIDVDKRKILLDEPIRSLGSTFVEIKIHQKVTTKIRVDVKEKQ"
     gene            31589..32917
                     /gene="dnaB"
                     /locus_tag="OE968_000927"
     CDS             31589..32917
                     /gene="dnaB"
                     /locus_tag="OE968_000927"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HCP7218240.1"
                     /translation="MEDMTRIPPHSVESEQSILGSILLDKDAIITVTETIKPDDFYKE
                     AHKIIYECMITLSNKGEPIDLITLTEELRKQGHLNDIGGISYITSLSTIVPTTSNVKY
                     YADIVKEKSVLRKLIKASNEIINLGYSGATKIEDVLEQAEKSIFDISQEKTSDDFKSI
                     NLVLMDAYDMIEKLYTNKSDVTGITTGFKDLNKKINGLQRTDLILIAARPAMGKTAFS
                     LNLVQNAALKGDASVAVFSLEMSKEQLVQRMLSSQSSVELKKIKTGTLNDNDWPRIID
                     AMAVLSDAKIHIDDTPGIKISELRSKCRKLKIEKGLDLVLIDYLQLMEGEGNNESRQQ
                     EISKISRSLKILAKELNCPVVALSQLSRAPEQRADHRPMLSDLRESGAIEQDADIVMF
                     LYRDEYYHADSESKNIGEVIIAKNRHGETGSVELVWLGEVQRFGDKLRDL"
     gene            33122..33430
                     /locus_tag="OE968_000928"
     CDS             33122..33430
                     /locus_tag="OE968_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218241.1"
                     /translation="MEKISLKYIYPNIIKVLDEINLFRVIDNNLRESIVVYANNVDNQ
                     YHINMTNTNFGNIINICKLEKLLDVDKFMEKVIKYEKEIIEKEEFSKIEEYMLNIGEY
                     "
     gene            33512..34801
                     /locus_tag="OE968_000929"
     CDS             33512..34801
                     /locus_tag="OE968_000929"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HCP7218242.1"
                     /translation="MKTVAIVGSQWGDEGKGKVIDYLATQADVVVRGQGGNNAGHTLV
                     VEGKKYALHLIPSGVLNPNTVNIIGNGIVFDPKGFLEELEMFKTDNISTENIKISDRA
                     HVIFPYHKELDALSEEARGDLKIGTTKKGIGPCYMDKTERSGIRICDLMDKDKFAIKL
                     KAQIDAKNEIVKNIYGKEELFDFETIYNEYLGYAEQIRKYVADTSVIVYDAVRAGKKV
                     LFEGAQGTLLDLDLGTYPFVTSSHPTSGGFAIGAGIGPNMIKDVVGIVKAYTTRVGEG
                     PFVTEQINETGDKIREQGHEFGVTTGRPRRCGWFDAVIVKYAARVNGLTSISFMLLDV
                     LTGFDKIKVCTSYKMGDKIITDFPASLDDLAKCEPVYEELDGWNEDITQIDNFDDLPE
                     NAKKYVAKIEELVGVSVDMVSVGPNRAQTIIRRNIFA"
     gene            35127..35202
                     /locus_tag="OE968_000930"
     tRNA            35127..35202
                     /locus_tag="OE968_000930"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35160..35162,aa:Lys,seq:ttt)
     gene            35209..35283
                     /locus_tag="OE968_000931"
     tRNA            35209..35283
                     /locus_tag="OE968_000931"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35242..35244,aa:Glu,seq:ttc)
     gene            35288..35363
                     /locus_tag="OE968_000932"
     tRNA            35288..35363
                     /locus_tag="OE968_000932"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35321..35323,aa:Val,seq:tac)
     gene            35397..35471
                     /locus_tag="OE968_000933"
     tRNA            35397..35471
                     /locus_tag="OE968_000933"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35429..35431,aa:Thr,seq:tgt)
     gene            complement(35854..36846)
                     /locus_tag="OE968_000934"
     CDS             complement(35854..36846)
                     /locus_tag="OE968_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HCP7218243.1"
                     /translation="MNEDKIRKILAKYAKRRDDNELLLEHRKNEVYNRIPEIKSIDDE
                     ISKIGLSLAKIVLLNPKSKDEIVKKTKENIESLKVKKERLLAESNIPLDYLEIKFQCI
                     SCKDKGFLPNGEKCSCLKQEIVNEAYKMSNLDRILSQENFSNFNLNIFSPKKGSDGEI
                     SPRENMLNNLSICENFVHDFKKDNSENLLFYGSTGLGKTYMCNCIAKELLDKGNVVIY
                     QTSFRILDILEDYKFRRDTNNQISEDNYKNLFDCDLLIIDDLGTELNNSFTSGEIFNI
                     VNTRLVAGKKIIISTNLTPSQIGNTYTQRTLSRILDKFRILEFTGDDLRWERFK"
     gene            complement(36855..37913)
                     /locus_tag="OE968_000935"
     CDS             complement(36855..37913)
                     /locus_tag="OE968_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HCP7218244.1"
                     /translation="MFFKESNEIDLGEITIPNIFIDIFMPMADGLYVKVYLLGYRQAC
                     DITSNPKFDNNSIAKNLNIPLSDVLSAWKFWEEKKIIKIHDNEEYDNFNYSIEFLDLK
                     NFYIENILSNNSSIKSNTDKVVSTSENPSIRKMFNSINKIVGRYLDPSEKMSIMDIMN
                     KYNMSPDMILCAYEYVKDKTGTSKPVKYIEGIIRNWYDSNLYTPKDVEESFLVRSERY
                     ILYKTIFNELGFSRQPSKSEKELMDTWFDKFNMDIDLIINACSKSKNISNPSISYING
                     IIKNWNEKNIKNLNDLKQKEEERIVKENINKKQINTTQNNNTYKKTKFHNFNETFTQY
                     TSDELDEIIKKSQKEKFK"
     gene            38038..39501
                     /locus_tag="OE968_000936"
     CDS             38038..39501
                     /locus_tag="OE968_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HCP7218245.1"
                     /translation="MVIKFNQKVRRTLSVAILFMVLIIGCFIEKDDSLETYKEKTNSK
                     INQYNMDVIFDDETKRLMCNQNVDYINNTKSNIDKIYFHIYPNAFSKKDFAPFEKSEM
                     TRAYPNGFNEGYIDIKNILNNNSKMEYKIKGDKNDILEIELGKELKPNERMSLDIKYN
                     VKIPNSIGRFGYGENTINVTNWFPIACVNDERGWNLKSYETIGDPFYSETSDFHVKLL
                     IPNKYKIAHTGKLIDDKHDNKKMLYEIEAENVRDFAFILSSKFDVNKVDSKGVAINTY
                     NLNKKLSKKATEVAKDSINIFSELFGKYPYKEFSVVASDFFIGGMEYPMLVMIDQSLY
                     NEKNEFLLEYVIAHETAHQWWYSAVGNDEISEPWLDEALTEYSTIVYFEQKYGKDMAN
                     KLIKTMEIQTKSYLSENIFKPANEYKNSTEYSLNVYTKGAIAFNEIRKEVGDKVFFET
                     LNEYYNKYKHKNANGRAFVELWNSKGVDINKIISECK"
     gene            39603..40400
                     /locus_tag="OE968_000937"
     CDS             39603..40400
                     /locus_tag="OE968_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HCP7218246.1"
                     /translation="MLKYCSVGSGSSGNCHYIGYKNTNILVDAGLSGKRITTGLKDIG
                     VDADKLKGIFITHEHVDHIKGAGILSRKFDIPVFANIKTWCSMKDKLGDIKDKNMKVF
                     ENDKTYSLGDIIVRPFSIEHDASDPVGYNFYTESDEKMSIATDIGCITQNIKKHLYKS
                     KLVVLESNYDPNMLMMGSYTYALKKRVMSSTGHLSNEDAANFCVELINEGTESILLAH
                     LSKENNFPELAYETSKGVLASNDIVVGQDVKLDVLSRNDVSNVYEMK"
     gene            40413..42515
                     /locus_tag="OE968_000938"
     CDS             40413..42515
                     /locus_tag="OE968_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC/EAL
                     domain-containing protein"
                     /protein_id="HCP7218247.1"
                     /translation="MLKRNFENVEDNKILYSIKQGMILAIPAIMTGSTALVILNLPIK
                     AYQEYLSGLFNGEVTNILNFINDSTLGIISLIILLTISYSYGKIYGSKYTVLVPIVAM
                     CSFLVFSHGNELNSYIEIFKTKWLFTSIIVSMTSSVLFVKLTESFVTSVKFHTEGADA
                     DFNMVVSAIVPFIIVVFLFSIFRVVMISLIGSSNFQDIFYNLFSNVFNKMGTNLMSAL
                     LFIFLMHFMWFFGIHGSNVLDTVAKNLFENSMAININLVNNNQLPTEIFTKTFFDTMV
                     LLGGCGSLLCLVIAIFLSEKRINVRKLAKIASIPALFNINEMLVFGIPIVFNYIMFVP
                     FVITPIILTVTSYVAMSTGIVPCTVSAVEWTSPIFLSGYMSTGSIRGSLLQVFNLCVG
                     VMIYIPFIKMSQNRYTYMFKNNIENLTNLLKRYELTGEQPNLLNHNGKIGSISKMLAS
                     DLKFAMKRGEIELFYQPQVNYNGNVVGAEGLLRWKHSIGGFIYPPLVIILAKEEGFLD
                     ELGEYIINKACIDLKKSEKLLRNPVKFSVNISPDQLDDPKLPEQIKNIISSNDINPNM
                     LGIEITEQIALSGSQIIIERINAIHNLGIKLIMDDFGMGHSSLIYLQNNNFDIVKLDG
                     SLVKEILTNKRSSEIIMTIVNLSKNLDFDIVVEYVENIDQRDKLYGLGCEIYQGYYYS
                     KAIPFEEFVEYANQEREI"
     gene            42583..43062
                     /gene="rlmH"
                     /locus_tag="OE968_000939"
     CDS             42583..43062
                     /gene="rlmH"
                     /locus_tag="OE968_000939"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HCP7218248.1"
                     /translation="MNISIVVVGKIKEKYLKLGIDEFKKRLSKYCKLEIIELDDEKAP
                     ENLSVKEMEIIKDKEGKKILGKIKHNSYVIALAIDGKGLSSEELAKTMSDLAVRGNSS
                     LCFIIGGSLGLSDEVLGRADYRLSFSKMTFPHQMMRLILLEQIYRAYRINNGEPYHK"
     gene            43211..43522
                     /locus_tag="OE968_000940"
     CDS             43211..43522
                     /locus_tag="OE968_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCP7218249.1"
                     /translation="MIKIMLACSAGMSTSLLVTKMESAAKENGIESQIWAIPESTIQN
                     EIEKCDVLLLGPQVRYVLPKAQEIAKPYNIPVEVINMMHYGTVNGEAVLNRAIELNNT
                     K"
     gene            43570..43887
                     /locus_tag="OE968_000941"
     CDS             43570..43887
                     /locus_tag="OE968_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HCP7218250.1"
                     /translation="MDEKTIEISFNIIGYAGEGKGLAFEAIKEAKNGNIEKAKELLKE
                     SREVINKAHRYQTELIQNEASGNRTEISVILIHAQDHLMNGMNFQQLAEEIVDLHLKL
                     QDK"
     gene            44100..44801
                     /locus_tag="OE968_000942"
     CDS             44100..44801
                     /locus_tag="OE968_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCP7218251.1"
                     /translation="MLRNQPLYIQVVDILKQKILNNEYKIDENIPTERELEQEFGVSK
                     ITIRKAIEILESEGYVEKKSGKGTKVISNSLFNKLSKAESFSSILLSKGHKLSKKTIS
                     IEKIINDTNSQVFSIFGEKCSKITRMYYLDSKPYIFFTHYIPFDENLTVESFNNESSL
                     YMYLYRRNINITRFEDEFFIEESELEVSKALNLAKDILLGRKRKTYDENDNIVELSFA
                     RYNTEVQNYVIKYEI"
     gene            45025..46326
                     /locus_tag="OE968_000943"
     CDS             45025..46326
                     /locus_tag="OE968_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCP7218252.1"
                     /translation="MEKFASFLERKIMPVAAKISNQRHMRAVRAGIIATLPLTIVGSF
                     FTILLNIPIDAYMDFIAPFKAILDIPFRYTVGFLSLYATFGIASSLAKSYDLDTTGVG
                     MLAVMAFLVSTIVPTQVVEPVGGVIEAGRWMDMAKLNSPSLFGAIVTSLITVEIYRFM
                     KEKNITIKMPAGVPVEVSNSFTALLPTAVILMLFWVIRHILGFDISVALSAMLSPLKG
                     FLSGNSLGGGLLTVFLITLFWVLGIHGPAIMGPVIRPIWDMSIAENITAFTEGVSAHA
                     MPNIFTEQFLQWYVWIGGAGATLALVVMFMFSKSQYLKSLGRLGFLPGLFNINEPIIF
                     GAPIVMNPILGIPFIIGPIIMTILSYVLTITGVIPMMVARLPFAMPAPIAAVMSTNWS
                     ILAGILVLINFVISFAVYYPFFKVFEKQQLQREQEEMSENL"
     gene            46463..47557
                     /locus_tag="OE968_000944"
     CDS             46463..47557
                     /locus_tag="OE968_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HCP7218253.1"
                     /translation="MERRLGISVYPEHSNMEDDKAYIKMASKYGFKRIFMCMLSITRP
                     KEEVKKHFKEIITYARELGFEVILDIAPNIFDILQISYDDLTFFSELNASGIRLDYGY
                     DGSKEAMISFNPYDLKVELNMSNDVAYLDNIITYKPNVNNIYGCHNFYPQRGTGLPYD
                     FFVRCSNRFKKYGIRTAAFVNSKYATIGPWNINDGLCTLEMHRNLDIATATKHLFATG
                     LIDDVIVGNAYASEDELKRMSEVNKYQVVFNVVTEEKTSEVEKTIMANEQHFRRGDIT
                     NQVARSTEVRKKYAKENFPKHDNTTIFKRGDVVIGNDDFGKYKGELQLILQDCADERK
                     NKVGRIKEDEIMLLDFIEPWSKFKLILEGE"
     gene            47559..48692
                     /locus_tag="OE968_000945"
     CDS             47559..48692
                     /locus_tag="OE968_000945"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase/deacetylase family
                     metallohydrolase"
                     /protein_id="HCP7218254.1"
                     /translation="MKIDILIKGGKTVDKSIIDIAILDDKIIEVKNQIDDSKYQANQI
                     INLDGEKFISAGWIDIHTHCYERLDLYKDYPDEVGIKSGVTTVVDAGTTGALDIGKFY
                     EDTKKYKTNVYALINIAKQGITSQDELSSMMNIDEYELKRAVKKYKDFVVGIKARMSK
                     SVVISNDVEPLKVAKRIKNELNLPMMVHFGSSPPTIEDIFDYMEKGDILTHIYNGKPN
                     GILRGNEVKKEIIEARERGIILDVGHGTESFSMDIAMKSKDAGIFPDTISTDIYIKNR
                     INGPVYNLSTTMEKFIYMGYSLEDIIDKVTKNAADAISLKNKGLIKEGYDADLTIFDV
                     VNEEKELQDSLNKSVITSTSIKPRAVVVNGEYLNIGKSIGENE"
     gene            48710..49819
                     /locus_tag="OE968_000946"
     CDS             48710..49819
                     /locus_tag="OE968_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DgaE family pyridoxal phosphate-dependent
                     ammonia lyase"
                     /protein_id="HCP7218255.1"
                     /translation="MSSIFEKYSVRRVINASGKMTILGVSTVDKEVIEAIGEGCKNFF
                     IIEELINKTGEYIANLLGCESALIVSSASAGIAQSVGAMIAKDDMSLVYNVNNPKKQV
                     KREIIIPKGHNVDYGVPVEVMIRLGGGEVVEAGYANMCNKEHIIREINENTAAIMYIK
                     SHHCVQKSMLSVLDAVQVAKEYNLPLIVDAAAEEDLNVYYELGADLVIYSGAKAIEGP
                     SSGLVIGKKKYIDNVKLQSKGIGRAMKIGKENIVGLTCAIERYISNDKVTLKEMEDKL
                     NPFIDKINTIKGVSASITRDSAGREILRGEIDFNEDIINKSTQQIINELRSGEIAIYT
                     RDYKANEGKIEIDIRSVTGSDLDTIYNRIKNIVES"
     gene            49884..50624
                     /locus_tag="OE968_000947"
     CDS             49884..50624
                     /locus_tag="OE968_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KDGP aldolase family protein"
                     /protein_id="HCP7218256.1"
                     /translation="MNCIPQYYKNRVCLNVLAGSIKNAKEVYDACDGYVLIGVLSKNY
                     STVEAAIEDMKKYSKEIDNAISVGLGAGDPNQSNMVSQISKELQPQHINQVFTGVATS
                     RALLGQNDSIINGLVSPTGKPGFVKISTGPLSSKEKDGIVPIETAIAMMKDMGGSSIK
                     FFPMGGLKTKDEYIEVAKACAKHNFYLEPTGGIDLDNFKEIVQIALDAGVEKVIPHVY
                     TSIIDKETGETKVEDIGVLYKIMKELLG"
     gene            50629..51621
                     /locus_tag="OE968_000948"
     CDS             50629..51621
                     /locus_tag="OE968_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HCP7218257.1"
                     /translation="MNILAFGEIMMRLSVPDYKFLTQTNELNYIITGTGLNILSGLKN
                     FGYNTYMLTKLPNNNVGKASSANIRKLGVKDDFITYGGNHIGVYFLENGYGERPSEVT
                     YLNRLNSSFCESKLQDYDIDKCLEEMDIVLICGIAMQLTDSIKEIALELARKSYEKGI
                     KVFFDFNFRQSLNPERTYDDLVNDYKKILPYCHGLFASYRDINKILNIDSLNIKSSSE
                     LIKKEYDIGIVAGTMRRFDDMNNRFIKGYISNDDGYFESREYKLEIYDRVGAGDGYVA
                     GIIYSYLENMKSEDIVEFGVASSVLAHTTYGDNSLVSTGHVLRLMNNEKIDILR"
     gene            complement(51809..52690)
                     /locus_tag="OE968_000949"
     CDS             complement(51809..52690)
                     /locus_tag="OE968_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCP7218258.1"
                     /translation="MNTKQLEYFISVAENLSFTKTAEKFYISQTAVTQQIKALEEQIN
                     VTLFTRSKRHVELTPAGKVFLSEARTIIKNINDAIAKTQQFAHGFFGTLSIGTLIGYE
                     KNKLQQYLKEFSNTYPNISMDICTNEITELLNLVKNNSMDLAFVINPENQPLKDFEYK
                     TVERYSLVALLPPGHPLYNEDSIDLIELQHDKFIFVKETGDEYGQKSMIQNRYREAGF
                     VPNVVQRSNNLNTIESLVSSNMGISILPSFCVTDTMIERDIAIVPIKEVENRIEVVVV
                     WNKKNTNPALEKFISII"
BASE COUNT        20044 a         6469 c         8610 g        17671 t
ORIGIN      
        1 atataaatta acctactgtt taattttcaa tgttcgtgtt tatttcttgt tccttttttc
       61 aaggacaagt aatactatac catctttaaa acagtaggtc aatacttttt ttatattttt
      121 ttataaattt ttttcatatt cttttttcag cttctctact acctttttct ctagtctaga
      181 aacagtcatc tgtgatatcc ctagttcttt agctatacta gattgtgttt tatcaaagaa
      241 aaatctatct ttaaaaattt taacttctaa ttcatttaaa gtttcaataa acttattaat
      301 aaaatcttca tactctatac ttccaaagtt accttcttct tttccaatct tatcaataag
      361 agttatatct ttatcctctg aatcatcatt acttgatgaa tccaaagaca ttggttgata
      421 tccataagaa gcctccatag cctctaaaac atcttcttca ctaacgccta tataatcagc
      481 tatatctttt acctttggat gcttcttatt ttcttgttct aatttaatct tcgcatcact
      541 tatctttttg cttaattcct gtattcttct tgggactcta agtgtccata ctttatctct
      601 aaaatacttt tttatttctc ctactatagt tggtgttgca aagctggaga actcaaatcc
      661 tttctcaaca tcatatctat caatagcata aattaatgcc aatgaagcaa cttgatatat
      721 atcttcaaaa tcaacacctt tgtttatata cttcttagct aacaatcttg ctaaatacag
      781 atgtctttca ataagaatat ttctaatgtc tacattttta tttttattat ataaattaaa
      841 tagctctttt gtatccatat ttaggtaatg tgtagcatta gctacatttt tcattaaata
      901 tcaactccta aatatttagt catttttatt tttgtccctt gattatgttc tgattcaata
      961 tctacatcat ccattaaagt tttaattata aacaatccaa gaccactctc ttttggattc
     1021 tctaaatctg gtgtacttat tgagctaaca tcatatcctt ttccattatc ttgaatttct
     1081 atattaattg cattatctaa aatattaaat actatattaa atacatcatc tttactgtgt
     1141 tttattgcat ttgtacatgc ttcagatact gctaccttta tatcttctat atcatctatt
     1201 ggaaaaccca tcttattggc aattccagat gctgttaatc ttattatact aacataatct
     1261 ggatttgtag taatttccat ctttatagtc tcacaagcca aagtttatcc ctccacttta
     1321 aatattttat ctagacctgt tatagtaaaa atctttctta cgttactctt aggatttact
     1381 atgtatatct ctttttcatt tatttttaat ttttttaata cacctatcat agctcctaag
     1441 cctgttgagt ctatataatc taaatcttta agattaatct ttacatctaa catatttttt
     1501 tctattaaag catgtaaatg ttcctttagt ttatctgctg tagaaacatc aagttctcca
     1561 tcaagacaaa cattccaaaa tttattttgt gaatctaaat ttgaatcaat attcatagac
     1621 atgtaaaaac ctcctatttc cttttaataa ttttaaatat atttcctata ctcaatattt
     1681 tattaattac ataaactata tcatctattc cctttgatat tgatgatgca ttttcaacaa
     1741 tatcttgtat atgtctttca ttataatcta caatcttata tgccttttca acaaccttat
     1801 ttatgctgtt tagagtttta gctaaataaa ttgctactat aagagcagag cttcctacta
     1861 acactgctcc aatttgccac ccccatgcat tcattagtta acatctccct catcatcaaa
     1921 gcttttactt attactatat cttcttctga aatctttata tcttcttcat tattatcatc
     1981 atccactaaa tttattattc tctctttaac atcattaaat gtttcatgta gaacttcttt
     2041 tggattttct ttaacatcat taaacttctc ttttgtttct tttcttagtt cagaaccttt
     2101 tttaggtgca aaaaacatac caaatataaa ccctaaaata gctcctaata ataaaaatcc
     2161 acctttttta caacttcttt tattgcacat aacaattact cctttcaatt ttaaattttt
     2221 atctaactac attatacaaa aagaatagga tatttatcct attcttcttc aatatttatt
     2281 ttggcaatcg aaactacatt gacttcatca ttcgtcttca ttaatttaac accacttgta
     2341 actcttccaa acagtgatat ttcattgact cttattctaa taagaactcc atcagaattt
     2401 ataatcatta tctcatcatc ttcgttgacc atatctgcac ctacaattgt accagttttt
     2461 tcagatatat tataagtttt aattccttta ccagctctta tttgacttct atactcttct
     2521 atatttgttc tctttccaaa accattctta cttacaacta acacatctgt acctttactg
     2581 caaaggttca tagacacaac aaaatcttct ttacttaaag ttataccttt tacacccatt
     2641 gctgttctac ccatatatct tatatcattt tcatcaaatc ttatagacat accttcttta
     2701 gttactaaaa gtacttcttg ttttccatct gtaagttcta ctccaataag ctcatcatca
     2761 tctcttaaac ctatagcaat aagaccagat ttatttatat ttttgaactc ttctctctta
     2821 gtctttttaa caataccttt tttcgttgca agtaataaat attcattttc atcattacca
     2881 tcaataggta ttagagtagc aattttctca tctgctgaca attgaagtaa attcactata
     2941 gcagtacctt tagcctgtct cttaccttct ggtatttcat atgcatttaa tttaaatact
     3001 ctacctttat ttgtaaagaa taatagtcta ctatgagtag ttgtagttac caagtgcctt
     3061 acaaaatctt cttctctagt tgtaagtgct gaaatacctc ttccacccct tttttgactc
     3121 ttataagtat cagatggaag cctttttata tatccaaagt gagtaagagt tattgctatt
     3181 tcttcatcac ttataagatc tctcatatct atttcgcctt cagcatgtct tatttctgtt
     3241 cttctctcat cagagtaatt ttcttttatt attgtaattt catcctttat tacatttaaa
     3301 agtaatcttt catcagctaa aatctctttt aatctattta tcttcttgat taaatcttca
     3361 tattcagctt ctatcttatc tctttctaaa cctgtaagtc tttgaagtct catatctaat
     3421 atagcttgtg cttggatttc agttaatttg aatttttcta ttaaacctag cttagcttct
     3481 tgcccagtct ttgaagctct tatcaagctt ataacagcat ctatattatc taaagcaatc
     3541 tttaatcctt ctaaaatatg tgctcttgct tcagctttat ttagttcaaa tttagttctt
     3601 cttgtaacaa catcttcttg atgtttaata taatgatata atatttgttt aagatttaaa
     3661 actcttggct gaccatctac aagtgcaagc attattatac taaaagtatc ttccatttga
     3721 gaatgtttat acaaattatt taatactata ttagcattag catccctctt taattctata
     3781 acaattctca taccatttct attactttcg tctcttaggt ctgatatacc ttctattctc
     3841 ttttctttaa ctaactctgc tattctttca accagtttag ccttatttac ttgataaggt
     3901 atttctgtaa ctattatttg ctgttttcct tttggtagct cttctataaa agctctagac
     3961 ctaactttaa cttttcctct tccagttctg tatgcttctg ctatactttc ttttcccatt
     4021 ataattgcag ctgtagggaa atctggtcct tgaacaaatt ttattaaatc atctacacta
     4081 cactctggat tatctatcaa atatacagtt gcatcaatta cttctgctaa attatgtgga
     4141 ggtattgaag ttgccatacc aacagctata ccatttgagc catttactaa taaattagga
     4201 tatctagctg gcaatactga aggctctttt aacgactcat caaagtttgg tttaaagtct
     4261 acagtttcct tttcaatatc tctcagtagt tctaatgata atttactcat tttagcttct
     4321 gtataacgca tagcagctgg tgaatcccca tcaacagaac caaagttacc atgaccatct
     4381 actaaaagtg ctctagttga aaaatcttgt gccattctta ccatagcata ataaacagca
     4441 gtatctccat gaggatggta cttacctaaa acgtccccaa caatacgagc tgacttcctg
     4501 tatggtttat ctggagttaa atttaactca ctcattgaat ataatattct tctatgaact
     4561 ggctttaaac catctctaac atcaggaaga gcacgtccag ctataacact cattgaataa
     4621 tcaatatacg attttttcat ttcttccgct atttcaatag ggagtatttt gttattttct
     4681 tccatgtata ctaatcccct ctctctatat atctaagttt ctaacaaatc ttgcattttc
     4741 ttctataaat tcttttcttg gagcaacctt atcacccata agcattgaaa atacttcatc
     4801 tgcaattgca gcatcttcta cagtaacttg taataaagtt cttgtctcag gattcatagt
     4861 tgtttcccat aattgctctg cattcatctc tccaagacct ttgtaccttt gaagttcaac
     4921 accatttctt ccaatttcat ctaataagat atttaactct ttatctgagt aaacataatg
     4981 ttccttcttt tgctttgtca ctttatataa aggtggctgt gctgcataaa catacccctc
     5041 atctataaga ggtctcatat atctaaagaa gaatgttaat aataaagttc ttatatgggc
     5101 tccgtctaca tcagcatcgg tcataattat aattttatga tacctagcct tatctatatc
     5161 aaaatcttct ccaataccac aaccataagc tgttatcata ttttttattt catctgaaga
     5221 tagtatccta tctagtcttg atttctcaac attaagtatt ttccctctta atggaagtat
     5281 agcttgacta tttctatctc taccttgttt agctgaacct cccgctgaat ccccttcgac
     5341 taagaatatt tcacttttag atggatcttt ttctgcacaa tctgcaagtt ttccaggtaa
     5401 agatgtactt tctaatacac tttttctcct tgttaattct cttgcttttt ttgcagcttc
     5461 tctagctctt tgtgctctta aagctttatc aactatgatt cttgctgttg atgggttttc
     5521 ttctaggaaa gaccccagtt catcaactgt tacactatca actatacctc tcataaagct
     5581 attacctagc tttgttttag tttgaccttc aaattgaggt tctggtaatt taactgatac
     5641 tactgctgta agaccttctc ttatgtcttc accaagtagg ttaacatcat tttcctttaa
     5701 aaatttattt ctcttagcat aatcatttac agttttagta agagctgctt taaatccact
     5761 taaatgagaa ccaccttcat gtgtatttat attgtttgca aaagaatata tgttctctgt
     5821 ataaccatct gtatattgca tagctagttc aacaaaacaa tcatcaacct ttttatctat
     5881 ataaactatg tcatcatgta taccagttct agatttattt aaatacttaa tatattctac
     5941 caaaccacct gtatagtgaa attcttttct tttttcttgt ccttctcttt tatcttcaaa
     6001 tactattttt attcctttat tcaagaaaga aagttctcta agcctatact ccaatgtttc
     6061 atatttaaac tctatttcat caaatattgt ctcatctggc ataaattgaa tcattgttcc
     6121 tttatcttga gattctccaa ctacttcaag cttagatgtt ggcaatcctt tctcatatgt
     6181 ctgcttatat ctctttccgt ttaaataaac ctctgctacc atccattttg acaatgcatt
     6241 aactacagaa acaccaactc catgaagacc tccagatact ttatatcctc cgcctccaaa
     6301 ctttcctcct gcatgaagat tagttaatac tgtttctaaa gttgatttac cagttttagg
     6361 atgtatttca acaggtatac ctcttccgtt atcttttact aaaacactgc catcttcatt
     6421 aatagataca tatatgtctg aacaatatcc ttgtaaagcc tcatctatac tattatctac
     6481 aacttcataa actaagtgat gtaaacctct agggcttgta ctaccaatat acatacctgg
     6541 tctttttcta acggcttcta atccctctaa tacttgtatc tgacttgcac cgtattcttg
     6601 tttcatttaa tttcctccat tctctatgct aataacatcg ccattttcaa tattaaatat
     6661 tgtaacattt ttttcatcaa atattttttt atgtgaaact tcagcacttg ttataaacat
     6721 ttgaacattg cttaaattat ttactaaaag tttttgtctt gcttcatcta actcactaaa
     6781 aacatcatct aaaattaata ctggatattc ttcaacttca ttttttatta attctatctc
     6841 tgataacttt aatgatattg aagcagttct ttgttgacct tgtgaaccaa aaagtcttgc
     6901 atctaaatca tttatgaata tatttaagtc atctttgtgt ataccatatc tggtagtctt
     6961 agattctata tcattaggtc tattcgatga caacttggct aaaaatttat tatatactgt
     7021 atctatagta tcttcatcag ttatatttat ttgattttta tatcgaattg ataatctttc
     7081 aactccatta gtcaaattca tatgcatatt ttcagatata ttagctatct tttttataaa
     7141 gtctctacgc aaaatataaa tataacttcc atactttgct aacgtatcat catatacatc
     7201 taataaagct tcatcaacat gtatattttt aagcacccta ctcctttgag aaagtgtttt
     7261 attataattg gtaagatatt tataatattt aggtataatc tgactaatct ctttgtctat
     7321 aaatgccctt ctttctttag gaccctcttt aaccaacctt aaatcctcag gagaaaatat
     7381 aacaacattt aagttgccaa gtagttcttg tatcttttgt aaaggaactt tatttattct
     7441 tatccctttt ttatcttttc caataattag ctctattaga ctatatttat tatattttga
     7501 aaaacttcct ccaatatata agttttcact attaaatcta accatttctt tatctttgtt
     7561 agtcctaaat gattttccaa aagaaagcat ataaatagat tctactatat ttgtctttcc
     7621 ttgaccattt ttaccaacaa gtagatttac tttcccatta aattccagat gcaacttttt
     7681 ataatttcta aaattaacaa gttgcaaact tttaagtttc acaaaaagtt ctcctttttt
     7741 acaatacttt tattttagtt ccttctattt caactatatc tcctgatttt atcttttttc
     7801 ctcttcttaa ttctatttca tcatttactg tcactaaacc ttcttgaatt aaaaattttg
     7861 catgacctcc tgttgatgca atctctgcta atttaagaaa ttgatccaac tttatatatt
     7921 ctgattctat agttatttca gtcataatag ttcctccttg tcactatttt aaacaaattc
     7981 ctattgatac actaaaagta tattatacca taaatatgct tataaaagga gttgtctaag
     8041 attagaaaaa ttttctacaa aagacaactc cttcatgtct gctatatatt tgatgatatt
     8101 cttactggaa gcagtaagta aatataatta acatcatctg ttggtttaat tatacaagga
     8161 tttacatttg tagtaaattc tataaatatt tcctcattat ctatattttt caaaccttcg
     8221 ataaaatatc tagaattgaa agctatatct aggtaatctc catctaaatc tatttcaact
     8281 tcttcataca catttccttt ttctgtatta gaagtaattg ccattacttt atctcttata
     8341 gataacttta taagattatt tttttctgat tgagacaata aagacgctct ctctatacta
     8401 tttaaaagtt ccttagtatt taatttaact ctgctgttat gttctcttgg caataatttt
     8461 ttataatcaa taaaatctcc ttcaagcaat cttgtaataa ttttcgtatc attaattata
     8521 aaaatagcat ttttttcgtt aaatccaact ttaacattat cctctccaga aagcaaacta
     8581 tttacatcta taagtgtctt tccaggaatt atgactttta tattttcagt taaactatca
     8641 accgaacaac tttttacagc taatctatat ccatcaattg ctactaaatt taagtttcta
     8701 tctacaattt ctaaaagttc tcccattaaa acaggttttg tttggtcctg tgagatagca
     8761 aatacagttt gtttaatcat attttttagg atttcttgag gtatgctata taaatcttct
     8821 tcatttaatt ctggtaattt aggaaattct tttgctgcat aacctttaat tttaaatctt
     8881 gaatttacac aatttatgta aatattattt tctgaatcag tttctatctc aacaaaggaa
     8941 tctggtaatt ttctaattat atctccaaat agccttgcat ctacaacaac atcacctttt
     9001 tctatgattt ctgcttgtac ataagtttct attcctattt cagcatcata tccagtaagt
     9061 tttaattgac cttcttctgt agatataagt atacctttta ataattctat tgttgttttt
     9121 ccattaatag ctttttgagc aattccaatt ctatttgcta ggattttttg attacaaatt
     9181 attttcaatg tggataacct cctctggctt tttatatata aaaataagtt aaaatcatag
     9241 tagtaatagt agtaggtgtt gttgataatg ttaataagta tgtataacat tataaataca
     9301 aagatattaa catgtgtata agatgttaat atctttgtta ttttagactt gataatttgt
     9361 taataatttt tgttcaaaaa aagtattaac aggttattca agagatataa acatacaatt
     9421 gtgtataaat tatcccttca aatctgatat aattttgtct attttagtct taatttcttc
     9481 actttcttct atatccttag atactttgtc atgagcatga attactgttg tatggtctct
     9541 acccccaaac tcttcaccta ttttaggaag ggataaatca gtaagctcgc gcgttaaata
     9601 catagctatc tgtcttggat aagctattga acgtgttctt tttttagaat taaaatcttc
     9661 catctttaaa ttgaatacag aagatacttt ttcttttatt ctgagaacat ttatttcttc
     9721 atttttagaa gttgttataa tatcttttaa agcttctgta gcaagatcaa aagatattac
     9781 cctattgcta agagaagaat aagcaaccac tctagttaat gcaccttcta gttcccttat
     9841 gtttgactta atattttttg ctatatatga cataacctca tttggcacat ctatacgttc
     9901 tagttgagcc ttttttctaa gtatagcaat tcttgtctca aagtcaggtg cttgaatatc
     9961 agttataagt cccatttcaa atctcgatct tagcctatct tctagtgtag gtatgtcttt
    10021 tggcggtcta tcactagata taattatttg tttgtttgct tcatgaagag tattgaatgt
    10081 atggaaaaac tcttcttgag ttctttcttt tcctgctata aattgaatat cgtcgattag
    10141 taatacatct acgtttctat atttattcct aaattcttcg tttttatcgt cttttataga
    10201 gtttataagt tcattagtaa atttttctga agaaacgtaa actacttttg agtctttttt
    10261 ttgactaaca atatgatgac ctatagcatg cattaggtga gtcttaccta atccaactcc
    10321 tccatacaaa aaaagtgggt tataagcttt agctggagat tctgcaactg caacgcatgc
    10381 agcatgtgca aatctattac tattaccaat aacgaatgta tcaaatgtgt attttggatt
    10441 tagattgggg taaagaactc tataatttaa atctgtgcta tcagaattta aatcagcaac
    10501 ctctttttcg ctcaatacaa atttaatatt atattttttt aatgacagtt gactaatagc
    10561 atcttcaatt aaatgtaaat atctattctc taagatatct ttattaaaat cactaggagc
    10621 cagtaagatt aaatcattaa gatgtatttt taatggtacg atgtttttaa aaaaggtatt
    10681 aaaacttact gaagttaagt caccttttat taattgtagg gttttgtccc ataaagaaac
    10741 tatatccata atataaacct ccgaacagaa taattaatat tttccacaaa gttattaaca
    10801 gaaaagcaaa aatatatata aattttacag aataactaaa tttatggata atggtgttga
    10861 taaattaata atagtataaa ttattaaaaa aatatgaaaa gatataaaca atatgtagat
    10921 aaagttataa ataacataaa catacaataa atggtgatta taactagagt attgtcagta
    10981 atcttaaaag ttatacacaa aagtatccac aagctgtgaa taatttctaa taagttgata
    11041 acatttatgc acattatcaa caagtatatt tataatatca aaatatatgt caaacttcaa
    11101 tgatttgtaa ctaatttatc cacaatatta actaattgtt gataaaaata taaacatgtt
    11161 aaaattactt tatttgtgta tataattgaa aaaaataatt tagaataaaa ttaaatagat
    11221 ttttactagt attttcaata aaaaaaatac ataatatata tatggtagat tttgtgatat
    11281 aagcgtccca aaaactcgtt gacaacagta gtaaaagtat ttataattat atgtgttatg
    11341 tttactttga gggtaaagtt attattttta taaacggaaa ataaaatctg aaaggcggtg
    11401 caaaataatg agtaaaagaa cttatcaacc aaaaaagaga caaagaagta aagaacatgg
    11461 tttcagaaaa agaatgaaga cgtctaacgg aagaaacgtg ttaaagagaa gaagagctaa
    11521 aggaagaaat agattaactc attaattaca aaagggccgc tgcaaaggtg gcctttttgt
    11581 gtaaataatt acaattcata gctgtgttta tggaggttaa ctatggactt taataggact
    11641 aaagggttga aaaaagactc tgattttaga aaagtatata aacacggcaa atcttttgca
    11701 aacaaatatt tagtaatata tatacttaaa aataaatcag attatagtag agtaggtatt
    11761 tctgtttcaa aaaaagtagg aaaagctatt actaggaata gagtaagaag attaataaaa
    11821 gaagcctaca gattaaatat tgatgaaaaa attaagcctg gatatgatat agtatttata
    11881 gcaagggtat ctagtaagga tgctactttt aaagacatag acaagtctat aaaaaattta
    11941 gttaaaagaa cggatatttc tatttaattg tatgctataa atatggaggt taatgacttt
    12001 gaataaaata atttatatat taaaggaaat aagtaagcat ttatcgaatt tatgtattta
    12061 tttagtgaga ttttatcaaa agtatatatc tcccttaaag ggacctacct gtagatttta
    12121 tccaacttgc tcacaatatt caatagaggc gtttaagaaa tatggatttg taaaaggtat
    12181 gtatttaacg ataagaagac ttttaaaatg tcatcctttt catccaggag gttacgaccc
    12241 tctaaaataa aagagagtaa ctattaggag gtataaaaaa attgaatata ataggaaatt
    12301 tcttaggatt gattcttaag gtaatatttg aatttgttaa tcattatggt atttctataa
    12361 tactttttac gatacttgta aagattattt tattaccatt aacaattaag cagactaagt
    12421 caacaaaggc aatgcaagat atacaacctc gtataaaaga gatacaagaa aaatataaaa
    12481 ataagccaga aaaacaaaat gaagaaattg ttaagttata tggagaagct aaaattaatc
    12541 cactatctgg ttgtttacct ttattaatac agtttcctat attaatagga ttatttagcg
    12601 ttttgagaga accagttgct catggcgttt ttgcaaacaa agctgcattt ttagcagctg
    12661 acaatgggtt tttatggata aaaagcttaa catcaccaga ttatgtatta gcagtatttt
    12721 caggagcaag tgcatatgtc atgcaaaaag taatgacacc aaaagatcag ttacaaggct
    12781 ctatgaaagt aatgacatat gtaatggcag gtatgtcttt ctattgggga tttatattcc
    12841 cagcaggact tacattgtac tggacagtaa gtaacttatt ctcaatagct caatattact
    12901 taataatgaa tcctttaaaa gctaaactgg ctgctaactc taaggaggaa aaagttaatg
    12961 agaaaaagcc taaaattaat aaaaagtaag agtaaagagg aagctataag taaagctata
    13021 gcagagttga atttaaaagc agaggatata gaagtagaaa tacttgaaaa tccaagtaaa
    13081 gggtttttag gttttatagg tgctaaagat ggtacttatg aaatttttgt tatcgagagg
    13141 gaagtagatg tagctaaaaa ttttatagag gtaatgttga aaaatgcaaa tgttgatgcc
    13201 aaagtcaatg tatctcaaaa agataattta atcatggttg atattgaagg caaagaagct
    13261 gcaagtttaa ttggtagaag aggggaaact ttagattcta ttcaattttt gactggatta
    13321 gctcttaata aaataaataa agattctcat acaagagtac ttgtagatat agaaaattat
    13381 agatcaaaac gagaagaatc tttaataaga tatgctaata aagttgctag agaagtagcg
    13441 aaaacaagaa aaactaaaaa attagattat atgaatccat atgagagaag aataatacat
    13501 tcagctcttc aaaatgacaa atatgtaatt acatatagtg aaggaaccga tccatataga
    13561 agattagtaa ttgagtgtaa aagataaagt caacctccta aacattaggg ggttttattt
    13621 tttaatatta ttaaatcatt aatggttggt taaatgtaaa tctatatgta aaaaattatg
    13681 aattaagagg tgataaattt gtttatagat gatacaattg cagcaatagc tacagcacct
    13741 ggagaaggtg gtataggtat acttagaata agtggagaaa aagctttgaa ggttgcagaa
    13801 gaaatcttta aatctatgtc tggaaagagt attgaagaat acaataagag aacattaata
    13861 tatggaaata tagtggataa tgaaaatgta attgatgaag ttttattggc atatatgaaa
    13921 ggaccaaatt cctatacagg agaagatgtt atagaaatta attgccatgg tggatttatt
    13981 tcggtaaaga agatattaga attaatacta tcaaaagatg ttagattagc agaggctggt
    14041 gagtttacta aaagagcatt cttaaatgga agaatagatt tatctcaagc agaggctgta
    14101 attgatgtta taaaagccaa aactgatata gctcatgaag ttgctcaaaa tcaattagag
    14161 ggttctttat caaagaagat aagagaattg agagataaag tcactgagat attagctcat
    14221 gtagaagttg ctatagatta tcctgaggaa gatattgagc atataacata tcaaactctt
    14281 aaagaaaaaa ctgatgaact taaaaaagac attaaaaaat tatatgatac agctgaaagt
    14341 ggaaaaatac ttagagaagg cttaaagacg gtaattgttg ggaaaccaaa tgtaggtaaa
    14401 tcttcactac ttaattctat tttaggagag aatagagcaa tagttactga tataccagga
    14461 actactagag atgttataga agagtttgta aacataaaag gtataccttt aaaaattgtt
    14521 gacacagcag gtataagaga tactgatgat attgttgaaa aaataggtgt tgaaaagtct
    14581 aaagaatcat ttactagtgc agatttgata gtaatggttt tagatgcatc tagaaagttg
    14641 tcagaagaag atatagagat attagaaaaa cttaaggata aacaaacaat agtgctgtta
    14701 aataagaatg atttgaaaca agagattgaa gaagaaaaaa tacttaaata tgtagaaaat
    14761 aatagtataa taaaaatatc agctttacaa caagaaggaa tagaagaatt gcaagataaa
    14821 atagagtcta tggtatataa aggtagtatc aaaaataatt ctagtttagt agtaacaaat
    14881 tcaagacata aagatgcact tagtaaagca tataaatctg caacagatgc tttaattgct
    14941 ttggaacaaa gtatgccatt tgactttgta gaagtcgatt taaaaaatat atgggactat
    15001 cttggatata ttaatggtga tacagtaaca gaggatttac tagataatat attccataat
    15061 ttctgtattg gtaagtaatg tacaaaagta aacttgtttt tattatagag atttttaaaa
    15121 aatttgaagt gtttctcatg aaacattaat tttgaaaaga aaggaattat aaatgataaa
    15181 gtttgaagca ggaaaatatg atgttatagt agtcggagca ggacatgctg gatgtgaagc
    15241 tgctttggct actgcaagaa tgggatataa aactttgata ataacaatgt ctttggattc
    15301 catagcatta atgccttgta atccatcaat tggagggact ggtaaaggtc aattagttaa
    15361 agaaatagat gccttaggcg gtcagatggg attaaatata gacaagacat atatacaaag
    15421 tagaatgtta aatactgcca aaggtccagc ggtacactct ttaagagcac aagcagataa
    15481 atttaaatat catgaagaaa tgaaaaagac attagaagat gaaccaaatc ttgatatagc
    15541 tatggatgaa gttgtagaaa tacttcatga aggaaatgtt gtaataggag ttggaactaa
    15601 actaggatgt tcatttaaat ctaaagctgt aatattggcc actggagttt atctgaactc
    15661 aaagatatat atgggtgaag ttgcatttta tgaaggtcct aatgcattag ggtatgcaaa
    15721 atatcttaca gatagcttag ttgagcttgg ccttagaatg agaagattta agacgggaac
    15781 tccagcaaga gttcatagag atagtataga cttctctgta atgtctttac aagagggtga
    15841 tgaaaaagta actccattct catttatgaa tgaaaatata gaaaaaaaac aagaaccttg
    15901 ttatttaaca agaactacag aagaaactca aaaagttata ctggataatt taaaaaggtc
    15961 tgctatgtat agtggagtaa tagaaagtac tggtccaaga tactgtcctt ctatagaaga
    16021 taaagtagta agatttagtg ataaaacatc acatcaatta tttatagaac cagaagggtt
    16081 aaatactaaa gaaatgtata tacaaggaat ttcaactagt ttaccttttg aagttcaatt
    16141 agatatgtac aaaactataa aaggacttga aaattgtaag ataatgagac ctgcatatgc
    16201 tattgaatat gattgtgttg acccaactca actaaaaata agtttggaaa taaagggtgt
    16261 tgagaactta tttagtgcag ggcaatttaa tggaacttct ggatacgagg aagcagcagc
    16321 tcaagggctt atggctggta taaatgcagt tagaaagata gaaggaaaag agccatttgt
    16381 attagaccgt tcagaagctt atataggtgt cttattagat gaccttgtta ctaaaggaac
    16441 taacgagcct tacagaatga tgacatcaag agcagaatat cgactatatt taagacaaga
    16501 taatgcagat atgagattaa ctcaaaaagg ttatgatata ggattagtta aaaaagatag
    16561 atatgaaagg ttcctaaata aaaaggctgc tgtagagaaa gaatttgaaa gactaaaaaa
    16621 tgaaagagtt acaccaaaag aagtaaatag tttgttggaa gaaaaaggag caacaccaat
    16681 aaaggttgga atatctctat atgaattttt aaagagacca gaggttactt acgaattgct
    16741 tgaagaatta gggaaaggcg ctggagaaga tgtttcaaga gaagttaaag aacagtgtgt
    16801 aataataact aaatatgaag gttatataga gaaacaattg aaacaaatag accaatttaa
    16861 aaaacttgag aataaaaagt tggatgagaa aataaattat tcatctatag aaggtcttag
    16921 attagaagct agacagaaat tagatgatat aaaacctatt tcaatagggc aagcatctcg
    16981 tatatctggt gtttctccag ctgatatatc agttttactt atatacctag aacaaatcag
    17041 aagaactaga ggtggcaaag gtgaataata tagaacttct gaaaaacggg attgaaggtt
    17101 ttaatataga tacgaatgac agtatgttag aaaaatttaa aatctataga gagatattag
    17161 ttgaatggaa taaaaagatg aatcttactg gaatagaaga tgaaaaagaa gtgtatataa
    17221 aacatttttt agactctatt tcagctgtaa aaaatggata tataaaaaat gggatgtcta
    17281 taatagatgt tggtacaggt gctggttttc ctggaatacc attgaaaata tgtttagata
    17341 gcttagaact tactttgtta gattcgttaa ataaaagaat aaacttttta gaggaagtta
    17401 gtagagtact agagttagat aatattacat ttatacatgg aagagctgaa gattttggta
    17461 aaaatgaaga ctatagggaa aaatatgatg ttgctacggc aagagctgtt gctggattac
    17521 cgattcttat ggaattttgt gtaccatttg taaaagttgg agggtatttt atttgcttaa
    17581 aaggtccgaa tgctaattta gagctagaag aatcacaaaa ggctattgat gttttaggat
    17641 tggagtatat tgaaaaaata gatgtagagt taccagaggt agatttaaat cataatatat
    17701 tagtttttaa aaaagtgatg gaaacaccag ttaagtaccc tagaaaagct ggtaaaccag
    17761 ccaaaaatcc tattaagtaa tgaaaaattt attattggta agcttaatta tttctcagga
    17821 aataattaag cttactgtaa aaaaacaaaa ataaaggaat tattaaagta gatgcagaaa
    17881 taaatttgta tgtacatata gagaacaaaa ataatttata tctaaaataa gagaggtatg
    17941 ttatggaaga taaaagagtt atggagatac ctatagaaga tgtagttcca aatccatatc
    18001 aaccaagaaa aatattttca caagtttcat tggaggaatt gagcaattct ataaaggtat
    18061 atggtataat tcaacctata acagttagag caaaagatgg caaatatgaa ctaattgcag
    18121 gagaaagaag attaagagca gctaaattag cagagcttaa aaccatacca gcaattataa
    18181 ataatatgaa cgatgaatct tctgctgttc tagcgttatt agaaaatttg caacgagaag
    18241 acttaaattt cattgaagaa gcaattggtt atgaaaactt aataaaagaa catgctttta
    18301 ctcaacagca attagcagaa aaattgggca aaaatcaatc tactgtagca aataagctta
    18361 gaatattaaa gcttccaaac gatataaaaa tgaagctaat agagaataat ttaacagaaa
    18421 gacatgctag agcatttctt aaactaccaa gtgaagattt aatgcaaagt gtgttagaca
    18481 aagtcataaa aaatgaattg actgttaaaa aaacagaaaa attgatacaa gatgtattag
    18541 aagaaactaa agttcaagaa gagcctgata aaaaacagaa tataaagggt gctatgagta
    18601 taagaattta cataaatact ataaagcagg cctttgatgc tatatcaaat acaggaattg
    18661 atgctaagta taatgaaata gataagggag attatatgga agttgttgta aaaatcccta
    18721 aaaaatagag attactgctt accagtaatc tttttttgta atataagcct tgtaatataa
    18781 attgatttat agacattatt tatacttaaa aaacacctat tcaacattta aaattaattt
    18841 aattcttaaa ggggggaaca tcatgggcaa agttatagct gtattcaatc aaaagggtgg
    18901 agtcgggaaa actacaacaa atgtaaattt aagtgctagc ttaggaactt tgggaaagaa
    18961 aatattagta ttagatttag acccacaagg aaatacaact agtggatatg gtattaataa
    19021 aaacgaagta gaaaatacaa tctatgaaat tatgttagat gggttacata ttaaagaagc
    19081 aataataagt actgaatttg agaatgtaga tgtagttcca tcagctactg aactatcagg
    19141 tgcagagata gagcttacat ctaaaactaa tagagagtat attttaaaaa attccataaa
    19201 agcggtaata gatgaatatg attatatatt tttagattgt ccaccctcac tggggatgct
    19261 tacaataaat tgtttaactg ctgtagatag tgttttaatt ccaatacaat gtgaatatta
    19321 tgctttagaa ggtgttagtc aattaatgga gactataaaa ttagtaaaat caagattaaa
    19381 tgctgatata gaaattcaag gtgttgtttt aagtatgttt gatggaagag ctaatttatc
    19441 aatacaagta gttgaagaag ttaagaaata ctttaaaggt agtgtatata caactttaat
    19501 tccaagaaat gtaagacttg cagaagctcc aagtcatgga aaacctgtaa tttattatga
    19561 taaaagatgt agagggtctg tagcttattt ggaactagca gaagaattta tagatttaga
    19621 agaggaggaa tggtagtatg gagaataagt ctaaaagaag taatagatta ggtagaggtc
    19681 ttagtgcatt gataccagaa attaaaggag aaacttcaga aaaagaaata gtcaacatag
    19741 atatagacaa aatatatcca aacgaagttc aacctagaaa gcaatttgat gaagaaaaga
    19801 taaaagtatt gtcggattct ataaaaaatt atggtgtttt acagccaata gtggttaaaa
    19861 tggatgaaaa taataaatat atgataatag ctggagaaag aagatttaga gcatcaaaac
    19921 ttgcaaataa aaatcaaata cctgctataa ttaaagatat agatatgaaa gatataatgg
    19981 agatagcctt aattgaaaac ttacagaggg aagatttaaa ttcaatagaa gaggctctag
    20041 catataagag tttaatagag cattacaatg taactcagga agaaatatca gaagctgttg
    20101 ggaagagtag acctcatata actaatacac taagactttt aaatcttgga caagatgtta
    20161 tagaaatgat agacagtggt agaattacag caggccatgg taaggcttta ttgagaattg
    20221 cagataaaga tttgcaactt caaatagcga aaaaaataga agaagaagaa ctttctgtaa
    20281 gagaagtcga aaatatagct aaaaaaatat ctgaaaataa acaagaagaa cctaaaaaat
    20341 ctaaacctaa ggatgtattt attttagatg ttgaagataa acttagaaat atatttggaa
    20401 caaaggtgaa tatttctaaa ggaaagaaaa aaggtaaaat agagatagaa tactataatg
    20461 atgatgattt aaatagtatt gtatcaatgc ttcttgaata gaacaaaaat ataaaacaga
    20521 gaggaagatt gttatgattt atttagataa tgctgcaact acatatccaa aaccagaaag
    20581 agtgtataat gctgttttag attgtatgaa aaattattgt gcaaatccag gtagagcagg
    20641 ccataaactt gctatgagag ctgctaggga gatatatgat acaagagaga atatagctaa
    20701 gttgttcaat gtaagtaatc ctatgaatat agtatttaca tctaatgcaa cagattcttt
    20761 aaatttagcg ataaaaggtg tattacaaga aggagaccat gtaataacaa cgtctatgga
    20821 gcataattca gtaataagac ctataaaagc attggaaaaa aggggtattg aaaatactgt
    20881 agtaaaatgc gattatgagg gatttttaga ttatgaagat ttagaaaaat caataaagaa
    20941 taatactaaa ttgattgtaa caacacatgc gtctaatgta tgtggaactt taatagatat
    21001 aaaaaaagtt ggagaaatag ctaaaaaaca taatatacta tttttagtag atgcatcaca
    21061 aacagcaggt gtttatgata tagacgtaaa tgaatgtaat atagatatgt tggcaatgcc
    21121 aggtcataaa tgcttatttg gacctcaagg aacaggtata ttatatgtaa gagaagggtt
    21181 gaacttaaat atattaaaag aaggtggaac aggtagtaaa tcagaagaaa tagttcaacc
    21241 agagttattc ccagataaat atgaatcagg aactcataat actccaggta tagcaggtct
    21301 taaccaaggt atactattta tatttgaaag aggaatcaac aatataagac aacatgaaga
    21361 agaattatgt caatatatga tagacaaatt agaggaagta ccagatataa agatatatgg
    21421 accaaaggac agtaaaaaaa gagcatcagt aatagctcta aatataggag atatggattc
    21481 tggagaggtt actttcttat tagatagtga ttataatata gcgactagat caggaataca
    21541 ttgttcacca ctagcacata ccactttagg tactttaaaa caaggtgcag taaggttcag
    21601 tataggatat ttcaacacaa aagatgagat agataaagca gtggaagctt tgaaaaaaat
    21661 ttcaaaaaat aaatagcatg agatttaata atatagaaat aaaaaaaggg gatatttcaa
    21721 aataaaaatt tgaatcatct ccttttttgt acaaaaaaga aaaggggttc ctaagaacct
    21781 ctaatctatt tgataatagt ttcaagaaat tactttaagt aatctccttc ttcaagaact
    21841 atatgaccac tttcgtaatt agaaccatca acagtaattt ttatttgttc aacattcata
    21901 ttttttatgt aagtacgagc aactgaatca agcattaaag tttctgcatc actacctaag
    21961 tttgactttg taaagtcaga gctaacatct aatataccag tttttacacc atcaatgtct
    22021 tttgtagtaa atgaatttaa ttttgcagat tctggaacaa ctttaagttt ttgaagttct
    22081 tcaaataaag tgttctcatc aattttattt aaatcaactt tattttcaat taaatctgtc
    22141 ttatctacat caaaagagta aatagtagct gattgagctt tagtttcttc ttttggagta
    22201 ggtttagctt tgttattagg aacctctttt tcagtattgt tttcttcttt tggttgctca
    22261 acatttgtat tgctcttagt ttctttttta gatgaatcac ttccattttg agcattagta
    22321 caaccaactg cgaatataga tatagataat atacttaaca ctaacattat tttcttattt
    22381 ttcataaaaa tttctcctct cttaaaaact attcttatat ataattatag tcgttatgag
    22441 caaatatatg aatacaaaat agtaacaaat ttaaaaaatg atttatttaa attaataaaa
    22501 ctcaaaataa actaaatttt agtcattttt atgggaaatc atttaatgta cagtgaaaat
    22561 attgtaaaat aaaagtagtg tttttaaaat aaatataagt tataattata ttataaaaaa
    22621 atgtcttcaa aaggtgggaa tagtatggaa attttgagct taggagaaaa gattaaaaag
    22681 ttaagaaaag aaaaaaacat gacattgaaa gaattagctg gagataggat aacagcagca
    22741 caaataagcc atatagagag agataaatct catactagtt atgaactgtt ggaatatcta
    22801 ggcgataagc tagatgtaag tgtagaatac ttattagaga ccaaggaaat gcaatcaaaa
    22861 aagataactg ataatttaat actacagagc gaaatttata taaaagaaaa tgaattaaac
    22921 aaggctgagg accaaataaa agaagtttta gatatatgta agagatacga tttaatggag
    22981 aactatggca gatgtaattt tttaatggct aatattaatt tgaaaaaatc taattataat
    23041 gatgctatag aaaactttga aaaggcattg tacttcttta taaaaaatag tgatagtgaa
    23101 aatatactta agtgttattt aaacataggg aaaatatata tgcaggaaga cttttataaa
    23161 ggtgctataa gccactttaa ttttgcagag gaaattttgt cagagagtaa atttgaggat
    23221 gttaacatac acaaggaact atatagtaag atggcatatt gttacataaa actagataat
    23281 ccaaatatgt cattgaagta catagaaaag ataaatgaaa tagataatag aaatgataga
    23341 aaagaagatg tcgatatttt ggtgttaaaa gcaaataata tgcttgagat tggaaaatat
    23401 gaagaatcaa gagattactt taaaaaagca ctaaaaatac ttgagagtga ggataataaa
    23461 actggattag caaatgtgta tttaacaatt tgtgatgttt acagaaaaat aggtgaaaca
    23521 gatagagtac ttgaatattc acaaaaggta tatgacataa agaaaaatga tgaagatgaa
    23581 tacatgatgt caggattatt taagataata gaagcatata tagataaaga agattatgat
    23641 ttagctagaa aatattgtaa gatagcctta gcttcatcaa taaaaaataa aaataaattc
    23701 aatgaatata aagcattgag attctatgct aatatgtata aaaatcagaa tgaagtaact
    23761 cttgcaattg aatatctgat taaatgcata aaaatagtat cagatttagg caacaataga
    23821 atattggcca atttatatat agacttaggt caattatatt caaatatatc aaaagaaaaa
    23881 gagttagaat attatcaaaa aggtgtattt atgtacaaaa atttagaaat aatgtagggt
    23941 aaataaacct ataagggtat agaaacaatc tataacaagc aagataatat ctatgataaa
    24001 atataaattg tatgaatatt tttaaggaga tgaatcagac aatgagtata aaaatagatg
    24061 cgagagggct tgcttgtcct aaaccagtta taaatacaaa aagagaattg gataacctag
    24121 aagaaggtgt tgtagttaca atagttgata atgaaacagc taaggagaat atattaaaac
    24181 ttgctaaatc tttaagttgt gaagcaaata ttgttgacga aaaagagaat tttatatcta
    24241 tagaaattag aaaaggtaaa aatatactag ataaacaaaa tgttgtagat aataaagaaa
    24301 gtgaattaga caatacatgt atatttatat cttcagataa gatgggactt ggaaatgacg
    24361 aattaggaaa agtgttaata aaaggattta tatatacatt aacagaatct aaaccttatc
    24421 ctaagtatgt acttttagtt aatggaggag taaaattaag tgctgaaaat gaagaaacca
    24481 tagaaaatct aaaaatactt gagaatatgg gtgtagaagt tttatcttgt ggtacttgtt
    24541 tagattatta taatttaaaa gacaaattac aagtaggtac agttacaaat atgtatacta
    24601 tagttgagac attaaagaat gcatcaaata ccatttctat ataatgtatg tatgtttaat
    24661 aatataaaac taacaataaa gattaactca aatagatagt cagaaaggat taagtaatga
    24721 atcaaatgta tatagtgtca tttaattcga cacatcatgc gataagatca gaaaagttat
    24781 ttggtgaaaa tagtctaaaa gtaatggctc ttccaacacc aagagaaata acagcaagtt
    24841 gtggaatatc aattaaattt tcttttgaag atatggaaaa gataaaaact attttggttg
    24901 aaaataatgt agatataaaa ggaatttatt gtataagtaa attagaaaat ggttcaaaag
    24961 aagtagagaa gttagattag gaggctaatt atttatgcca atggatttaa aaataggtga
    25021 tattgttgaa ttaaaaaagc aacatgcatg tgggtgtaaa gagtttgaaa tcataagaac
    25081 gggaatggat ataaagataa aatgtactaa atgttcaagg ctaataatgc ttgatagaga
    25141 gaccttagaa aagagagtaa aaaagctaat aaaaaagtga taaaaattta acacttaaaa
    25201 aatgtcaaat accgtatatt aatatccaaa attttggtat aataagaatt gaagaaaaca
    25261 ttttcatggg ggtgctttaa ttatggcagt taaatatgca aaaagaatgc aaggattaca
    25321 aggatcagaa atacgtgagc ttttaaaact tactcaacaa ccacaaataa tatcttttgc
    25381 tggtggaatg ccggctccag agttatttcc agttgaggaa atgaaaaaag tatcagttgc
    25441 agtgcttgaa gaaaatggaa gatcagctat gcaatatact acaacagaag gatatgaacc
    25501 attaagagaa aaaatagcag ctagaatgaa tgataaaaac aaaactaatg taaacaaaga
    25561 tgatatatta gttacaagtg gttctcaaca aggtctagat tttgcaggaa aagtatttat
    25621 tgatgagggt gatgtaattt tatgtgaaag tccatcttac ataggagcta taaacgcatt
    25681 taaatcttat caacctaaat tcatagatgt tccaacagat tctgatggaa tgataatgga
    25741 agaattagaa aagatactag aaacaactga tagaataaaa atgatttatg taatacctga
    25801 cttccaaaat ccaacaggaa gaacttggcc acttgaaaga cgtaaaaaat tcatggaaat
    25861 agtaaataaa tttgaaatac cagtaataga agataatcca tatggagatt taagatttga
    25921 aggagagact ttaccatctt taaaatcaat ggatacaaaa ggattagtaa tattcttagg
    25981 aactttctct aaaatattct gcccaggata cagattagga tggacttgtg cttctccaga
    26041 aattttatct aagtttaact ttgcaaaaca aggtgcagac ttacaagcat caactatatc
    26101 tcaaatggaa gtaagcaaat ttatggatat gtatgaccta gatgcacatg ttgacaaaat
    26161 aaaagcagtt tatgttaaac gtagagatgt aatgcttaag actatggaag aagagttccc
    26221 agaaggatta gtatttactc atccagaagg tggattattt acatgggtag agcttccaag
    26281 taatttaaat gctaaagaat taatgccaaa atgtttagat aagaatgttg cttatgttgc
    26341 tggaggagga ttcttcccta atggtggtag agaaaatact ttcagactta actattcaaa
    26401 tatgccagaa gaaaaaataa tagaaggtat aaaaaatata gcagctgtat taaaagaagc
    26461 tatgggtgta gaagcttaat taaaaataat aacttatata taatacaagg gatggttgtt
    26521 gccatccctt gtttgtttga aaagtatata attcacctta tactaaactt tgtccaaaat
    26581 ttaaattgac agaaataaga ataaatgata aaatgtgtag gtatgagatt ttagtctcat
    26641 ttctctgctc taagagtgta gagccgttaa gtccaaaggg aggtgaatta tagtgagaaa
    26701 ttatgaatta gtttatgtgg taaagccaaa ctctgatgaa gaagtaagag aggctatact
    26761 aaacaaagtt aaggaagttg ttgcaactga cggagaaata gttaaagttg atacttgggg
    26821 aactaaaaaa ttagcttatc caatagctaa gtttacagaa ggtttctatg tattagttaa
    26881 cttcaaatca gcagtagacg ttcctaaaga gatagacaga aacttaaaga taaatgaaaa
    26941 cgtaataaga cacatgatag ttgttgctta ataactggtt ttattataaa aaataggtgg
    27001 tgtttttatg aatcaagttg tattagtggg aaggttgact agagaccctg aattaagata
    27061 catcccaggt acaggaacac cagtggcatc ctttacaata gccattgata gagactatgt
    27121 aaaaaaagat ggatctaaag aaactgattt tatacctgtt gaagtaatgg gtaaatctgc
    27181 tgaattttgt gctaactaca taactaaagg tagattagta gcacttcaag gatctataag
    27241 agtagacaat tatcagacac aatcaggtga aaagagaact tttacaaaag taagtactag
    27301 atcagtacaa gctttggata gtaagaataa atcggaaaat tcatatagag agagtgctcc
    27361 agcttttgag ccaagctttg aacctcaagg tttagaccca caaggtttcc aagctataga
    27421 tgatgacgat ataccatttt aaaaaggagg gaaaaaagtc atgatgaata aaaaaagacg
    27481 taagaaaaaa agagtttgtc aattttgtgc tgacaaaaac gctaaaatag attacaaaag
    27541 tactcaaaga ttacaaaagt atataactga aagaggaaag atattaccaa gaagaatatc
    27601 tggaacttgt gctaagcatc aaagagaatt aacagttgct ataaaaagag cgagaaatat
    27661 agcactttta ccatatacat tagactaaaa aaatgagcct tgtgctcatt ttttattata
    27721 tgtatttata tatctaaatg aggcgagcta taaagctcgt ttttttgttt atatacttaa
    27781 atatattatt atttatgata taatattata tattaaggag ggttgtaaac gtgaaaatag
    27841 ataaaggttc tgagataacg agaaacataa agataataga atggatgaaa acagaaatat
    27901 taatgagtgt aagtgatttg tttaatttat tgtttaaagg ggtaaaacca ttagatgaag
    27961 caattcaaga tactttagca aatataataa tgataacata tctcttagca aagagattag
    28021 gaattagttt tagagatgtg gattataaag tcaaggaaaa aataaaaatt ggtatagatg
    28081 aggaccatag cgttgaaaga tggtatggag atttatctaa tttaaaaaaa catatggata
    28141 atagggagtg atattaaatt gaataataaa attagactat ctaaggcaat gtctataata
    28201 gttttagcta taataatcgc tttagtaata gcctatattc caatgctagg aatatttagt
    28261 atgttagcag ctgttccata tgtaattata ggtgctatta ctgatagaaa gtattctctt
    28321 atatctattt tggttacatt ttgtgtactg attctatttg cagacatttc ttatgcatta
    28381 aatatatgta taatgtattc tttaccaggt atagtaatag gaaagatgct aaagagaagc
    28441 tttgaacaag aggacagtaa taaattcgaa ccgatatatg gtggaaccat aatatttgta
    28501 ctttcaatgc ttgtatattt ttttgtatta aagacatttt taaatgtgaa tctattagat
    28561 gaagtttcta agatgatatc agaaattgta aatattcaaa aaaatagttt ttctgcaact
    28621 gaacttaaag tgtttgataa aatgaagcca gatgagattg taagttattt tacaaatatg
    28681 ctaccaatga tgttattttt acaagggttg ttatcagcgt ttgtcacata ttatttgagt
    28741 gtatttttta taaaaaggat tacaaagatg aatataagat ttcctaagtt tgctgatttt
    28801 tatttaccgg gaaatgctat actcacaact ttcttacttt atttattagt cttatttatt
    28861 caaattattg gttcaaaatt atatacagaa ttaataatga ctaatttaca gctagttttt
    28921 aatttaatgt ttgtaattca aggtatagca gtttgcattt atttcttaaa gaaatggata
    28981 agacagggac caaataaaat tatgtttttt tcagggataa ttttatgttt atttggattt
    29041 atgggaatat cttttgttgg tatggtagat agtataattg actttagaaa ggtaagaagc
    29101 tataaatcca cttaggagga tagaaatgag taataaacaa acctttaaat taaatatgcc
    29161 agaaataaat ttatatataa ttgttattgg tatttctagt ataattttgc tttattacaa
    29221 cttgtatgta gggtgtttat ttttctgtat ttttgtatat atggtttttc acaattggag
    29281 aactactaat attagacgtc atgaatggac agagtatatt caaaatttat ctttagatat
    29341 agatgaaaca actaaaaaag ccataataaa tcttccaata ccattatgta ttttagaatt
    29401 tgatggaaat atatcctggt ataatggaaa gttttatgat atgattggtc aaaaagattt
    29461 acttgataaa aatatagagg atatagttaa aaatcttaat ttaagaaaag tattaaatga
    29521 aaataaagag atgtacacag aaataaacta taaagaaaaa gaatatacaa taatttataa
    29581 tgttataaaa aatgatcaag aaaaaaatcc taaatatttg atgatattat actggataga
    29641 caagactgaa tatttaaaag taaaacaaaa ttatgatgat gaaaaaaatg caatgatgct
    29701 aatacaagta gatggatatg atgaagtatt aaaaagtgca gcagaagata agagagcttt
    29761 aattaatgtt gaagtagaga aaatactttc tgctttagaa ttaaattcaa atggtgcatt
    29821 gagaagaact tcaaaagaca aattcttctt ggtaatgcat aaaaaagagt taaaaaaatt
    29881 ggaagctgag aagttttcta ttttagatac aataagacat attgattatg gaaataatct
    29941 tcctgttact ataagtatag gaattggtat agatggagat acattaaatg agaacctaaa
    30001 acttgctacg ggtgctctcg atttagcact tggtagaggt ggtgaccagg ctgttgtaaa
    30061 aacaaaagat aaatttgtgt tttatggagg aaaatctaaa gctgtagaaa agaaaaccaa
    30121 agtaaaatcc agattaatag gtcatgcttt aagagaggtt atacaacaaa gtgaccaagt
    30181 ttatataatg ggacataaat atcctgatat ggatgctatg ggagcagcag ttggtgttta
    30241 tgatatatgt aaatcctgta acaaaactgc aaacatagtt ttacaatctg taaatgaatc
    30301 tatagaaata tttataaata aaataaatga aaataattac tataaaaagt tgtttattgg
    30361 aaaagaggaa gctattgaca actgcactaa aaatacatta gttgtagtag ttgatactca
    30421 tagaccaaat tatactgaat gtgaagaact gttaaagcta tcagagaagg tagtagttat
    30481 agaccatcat agaagaggtg tagagtttat aaatgatgca gtgcttttat tccatgagat
    30541 atatgtatcc tcaacgtgtg aaatggttac agagttagtt cagtatatgg atgaagatgt
    30601 aacaataaat aaacttacag ctgaagggct tttagcaggt ataagtctag atactaaaaa
    30661 ctttgcattc aaaacaggtg ttagaacttt tgaagctgct tcttacctta gaaaagttgg
    30721 agcagatact atagaggtaa agaaattctt caattctgat gtaaaagatt tcataataaa
    30781 agctgaaata attcaaagta ctaaaataat taataataga atatgtttag catattcaag
    30841 tactgagata gatagtataa atgttataat agctcaaact gctgatgagt tattaaatat
    30901 caaagaagta gaagcttcct ttgtattagg tgaaaaagat gatactatat ttataagtgc
    30961 gaggtcttta ggacaaataa atgtacatgt acttatggaa aaattaggag gcgggggaca
    31021 catagatata gctggagcac agttaaaaaa tgtttctcta aaagaagctt ataagatggt
    31081 aaataaaata atagaggagt atttggagga ggaagaatag atgaaagtta tattattaaa
    31141 agacgtaaaa ggaactggta aaaagggaga aatgaaagaa gtaagtgatg gatatgcaag
    31201 aaatttctta tttcctaaaa agatggctgt gcaagcagat agtgtagcaa taaaagaatt
    31261 aaatgaaaag aataaatcta aagaaataaa agcacaaaaa gagtatgaag aagcagtttt
    31321 attaggtaag caaatggaag aaattaatat agaaatatat tcaaaagcag gagaaggtgg
    31381 aagattattt ggttcaataa cttctaaaga aattgctgag caattaaaga aacaaaaaga
    31441 catagatgta gataaaagaa aaatattatt agatgaacca ataagatctt taggttcaac
    31501 tttcgtagaa ataaaaatac atcaaaaagt aactactaaa ataagagtgg atgtaaaaga
    31561 aaaacagtaa taactagagg tgattaagat ggaagatatg acgagaattc ctcctcatag
    31621 tgtagaatca gaacaatcaa tattgggttc tatacttcta gataaagatg ctataataac
    31681 ggttacagaa actataaagc ctgatgattt ctataaagag gctcacaaaa taatatatga
    31741 atgtatgata actttaagta ataaaggtga gcctatagac ttgataacat taacagaaga
    31801 actaagaaaa caagggcatc ttaatgatat tggaggaatc agttatatta caagtctttc
    31861 tactatagta ccgacgactt caaatgtaaa atactatgct gatatagtaa aagaaaagtc
    31921 tgtacttaga aagcttataa aagcttctaa tgaaataata aatctaggat atagtggagc
    31981 aactaagatt gaagatgttt tagaacaagc tgaaaagagt atatttgata tatcacagga
    32041 gaaaactagt gatgatttta aatctataaa cttagttttg atggatgcct atgatatgat
    32101 agaaaaatta tacactaaca agagtgatgt cactggtata actactggtt ttaaagattt
    32161 aaacaaaaaa ataaatggtc ttcaaaggac tgatttaata ttaattgcag ctagaccagc
    32221 aatgggtaaa actgcctttt ctttaaactt ggttcaaaat gcagccttaa aaggtgatgc
    32281 ctctgtagct gtatttagtt tagagatgtc taaggaacaa ttagtacaac gtatgttatc
    32341 ttcacaatct agtgtagaat taaaaaaaat aaagactgga acacttaatg ataatgattg
    32401 gcctagaatt atagatgcta tggcagtatt atcagatgcc aaaatacaca tagatgatac
    32461 tcctggtata aaaatatcag aactaaggtc aaagtgtaga aagttaaaaa tagaaaaagg
    32521 actagattta gtgcttattg attatcttca acttatggaa ggtgaaggta ataatgaaag
    32581 cagacaacaa gagatatcta agatatcaag gtcactaaaa atattagcaa aagaattaaa
    32641 ctgtcctgta gtagcactat ctcagttatc acgtgcacca gaacaaagag cagaccatag
    32701 acctatgtta tctgatttaa gagagtctgg agcaatagaa caggatgcag atatagttat
    32761 gttcttatac agggacgaat attatcatgc tgattctgag agtaaaaata taggagaagt
    32821 aataatagca aaaaatagac acggtgaaac tggttctgtg gaacttgttt ggcttggtga
    32881 agttcaaaga tttggggata agttgagaga cctataatct aacgaatatc cacagaacgt
    32941 cctttctttc tacaggaaaa atgtggatac atgtcactaa atatgtccaa acattgaaat
    33001 ttagctaaaa aactatccac actatccaca gatggcctgt tgataagtgt gaataagtag
    33061 ataaagcaag cttttggctt gctttatctg tgtataaata ttaattatta ggaggaataa
    33121 tatggaaaaa ataagcttaa aatatatata tcccaatata attaaagtac ttgatgaaat
    33181 aaacttattt agagtaattg acaataattt aagagaatct attgttgttt atgctaataa
    33241 tgtggataat cagtatcata taaacatgac taatacaaac tttggaaata taattaacat
    33301 atgtaaatta gaaaaacttt tagatgtgga taaatttatg gaaaaagtta taaaatatga
    33361 aaaagaaata atagagaaag aagagttttc aaaaatagaa gaatatatgt taaatattgg
    33421 agaatactaa aaaagttgaa aaaaatacga atgtttgata gaataagtaa gtaaagtgtt
    33481 cgagagtata taaaatatag aggtgaatta catgaaaaca gttgcaattg ttggttctca
    33541 atggggagat gaaggtaaag gtaaagttat agattatctt gctactcaag cagatgtagt
    33601 agtaagaggg caaggtggaa ataatgcagg acatacatta gttgtagaag gtaaaaaata
    33661 cgcattacat ctaattccat ctggagtttt aaatccaaat acagtgaata taatcggaaa
    33721 tggaatagtg tttgacccta aaggattttt agaagaattg gaaatgttta aaacggataa
    33781 tataagtaca gaaaatataa aaataagtga tagagcacat gtcatattcc catatcataa
    33841 agaactagat gcattgtcag aagaagccag aggcgattta aagataggta caacaaaaaa
    33901 aggtattgga ccttgttata tggataaaac agagagatct ggtattagaa tatgtgactt
    33961 aatggataaa gataaatttg ctataaaatt aaaagctcaa atagatgcta aaaatgaaat
    34021 agttaaaaat atatatggaa aagaagaatt atttgatttt gaaactatat ataacgaata
    34081 tctaggatat gcagagcaaa taagaaaata tgtggcagat acgtctgtta ttgtatatga
    34141 tgcagtaaga gcaggtaaaa aagtattgtt tgaaggagca caagggactt tattagattt
    34201 agatttagga acttatccat ttgttacatc ttctcatcca acatctggtg gatttgcaat
    34261 tggtgcaggt atagggccaa atatgataaa agacgttgtt ggtatagtaa aagcatatac
    34321 tacaagagtt ggagaaggac cgtttgttac agagcaaata aatgaaactg gagataagat
    34381 aagagaacaa ggacatgaat ttggggtaac tactggtaga ccaagaagat gtgggtggtt
    34441 tgatgcagtt atagttaagt atgcagctag agttaatgga ttgactagta tttcatttat
    34501 gttacttgat gtattaactg gatttgataa gataaaagtt tgtacgtctt ataaaatggg
    34561 cgataagata ataacggatt tcccagcttc attagatgat ttagcaaaat gtgaacctgt
    34621 atatgaagaa ttagatggat ggaatgaaga tataactcaa atagataact ttgatgacct
    34681 tccagaaaat gcaaagaaat atgtagcaaa aatagaagaa ctagttggag taagtgtaga
    34741 tatggtttct gttggtccaa atagagctca aactataata agaagaaata tatttgctta
    34801 atattttatc aattaaataa tttaaaatag ttgaagaaga gtatctcaag ataatgttta
    34861 tagttattag agatgctctt ttatatttga cttacattga ttttttatta agttaaagct
    34921 acttatacat attctaactg aaattaaagt tgaatttatg tagatacata taggtttttt
    34981 aaaaagaatt ttgttgaaaa taaatggcta aagatgattt taattatatt ctaaaaaaag
    35041 taaaaaaaac tattgactaa aaattatata gacgctataa tataacttgt gagtgaaaga
    35101 aacgacgaaa aaagtcgaaa aaatgtggtc tattagctca gtcggtagag cacctgactt
    35161 ttaatcaggg tgtcccgcgt tcgagtcgcg gatagatcac caaaatatgg ctcgttggtc
    35221 aagaggttaa gacaccgccc tttcacggcg gtaacagggg ttcaattccc ctacgagtca
    35281 ccagtatggg actatagctc agctgggaga gcacctgcct tacaagcagg gggtcacagg
    35341 ttcgagccct gttagtccca ccaaattttg aattagagat aaatactaga ttatatgctg
    35401 gtgtggctca acggtagagc agctgacttg taatcagcag gttgtaggtt cgattcctat
    35461 caccagctcc acaaagtaca taaattcaaa ttaatataat tttctatgtt acaggatact
    35521 tttaagtatc tttttttaat ttcattttta ttgtattaaa aatgaaatta aacatacaac
    35581 aaaattttga attacttgca atgtgatagt tttaaatata aaatttagaa tcattctagc
    35641 ataatattat gtaatatagc aaatttaatt tatagtatca ataaatatag actactaaga
    35701 atgtaaatga tttgttagat taaggtacat tagatatgta aatagaaaaa taaaaagtat
    35761 gttttaattt atgtgatata agttttaaac agagaagcaa gtttgctctt acctctctat
    35821 ttaaaaataa aaaaatgttt tttaagggct attttattta aatctttccc atctcaaatc
    35881 atctccagta aattctaaaa tcctaaactt atctaatatt ctagagagag ttctttgagt
    35941 gtaagtattt cctatttgag atggtgttaa gttggttgaa ataatgattt ttttaccagc
    36001 aacaagtctt gtatttacaa tattgaagat ttctccacta gtaaaagaat tattaagttc
    36061 agttccaagg tcatctatta ttaataaatc acaatcaaac aagtttttat aattatcttc
    36121 acttatttga ttatttgtgt ctcttctaaa tttataatct tcaagaatat ctaaaattct
    36181 aaaagaagtt tgatagatta caacattgcc tttatctaac aattcctttg caatacaatt
    36241 gcacatatag gtctttccta gtccagtaga accataaaac agtagatttt cactattatc
    36301 cttcttaaaa tcatgaacaa aattttcgca gatacttaaa ttatttagca tattttctct
    36361 aggagatatt tcaccatcag agcctttctt aggagaaaat atattcaagt taaaattcga
    36421 aaaattttcc tgacttaaaa tcctatctaa attagacatt ttataagctt catttacaat
    36481 ttcttgtttg aggcaagaac atttttctcc attaggtaaa aatcctttat ctttacaaga
    36541 aatacattga aactttattt ccaagtaatc aagaggtatg ttactttcag ctaaaagtct
    36601 ttctttcttt acttttaaag attctatatt ctctttagtc ttctttacaa tttcatcttt
    36661 agacttagga tttaaaagta ctatcttagc taaactgaga cctattttag aaatttcatc
    36721 atctatagat tttatctcag ggattctatt atatacctca ttttttctat gttctaataa
    36781 gagttcatta tcatctcttc tcttagcata tttagcaagt atttttctta ttttatcctc
    36841 attcatttaa tcacctactt aaacttttct ttttgacttt ttttaataat ctcatcgagc
    36901 tcatcagagg tatactgagt gaatgtttcg ttgaaattat gaaacttagt ttttttgtaa
    36961 gtattgttgt tttgagtagt attaatctgc ttcttattaa tattctcctt aactatacgt
    37021 tcttcctctt tttgctttaa atcatttaaa ttttttatat ttttttcatt ccaattttta
    37081 attataccat ttatataaga tatacttggg tttgaaatat tcttagactt agaacatgca
    37141 tttattatca aatctatatc catattaaat ttatcaaacc aggtgtccat aagttctttt
    37201 tctgattttg atggttgtct tgaaaatccc aattcattga aaatcgtttt atataaaata
    37261 tatcgttcac ttcttaccaa aaagctttct tcaacatctt ttggcgtata taaatttgaa
    37321 tcataccaat ttctaataat gccttcaatg tatttaactg gctttgatgt accagtttta
    37381 tctttgacgt attcatatgc gcaaagtatc atatcggggc tcatattgta tttattcatt
    37441 atatccataa tactcatctt ttcacttggg tcgagatatc gcccaactat tttatttata
    37501 gaattaaaca tttttctaat acttggattt tcagaagtag atacaacttt atctgtatta
    37561 gattttatag atgaattatt gcttaatata ttctcaatat agaaattttt taaatctaaa
    37621 aattctattg aataattaaa attatcatat tcttcattgt catgtatttt tataatcttc
    37681 ttttcttccc agaatttcca agcagataac acatcagaca atggtatatt taggtttttg
    37741 gctattgaat tattgtcgaa cttaggatta gaagtaatat cacatgcttg tctatatcct
    37801 aaaagataaa cttttacgta taacccgtcc gccattggca taaatatatc tataaagata
    37861 ttgggaatag tgatttcacc taaatctatt tcattgcttt ctttaaaaaa cattttatca
    37921 cctcagatta aattatatca ttttttatat tatatttgtc tgtaaacaaa taaaaggtca
    37981 caagattagc atgtaaatat tttctaaaag tattcatttt gaaaaggagg agatattttg
    38041 gttataaaat tcaaccaaaa agtaagaaga acattatcag tagcgattct atttatggta
    38101 ttaataatag gttgctttat agaaaaggat gacagtttag aaacatacaa agaaaaaact
    38161 aattcaaaaa taaatcagta taatatggat gttatatttg atgatgagac taagaggtta
    38221 atgtgcaatc agaatgttga ctacataaat aatacaaaat caaacataga taaaatatat
    38281 ttccatatat atccgaatgc tttttccaag aaagattttg ctccttttga aaaaagtgaa
    38341 atgacaaggg cttatcctaa tggatttaac gaaggatata tagatataaa gaatatatta
    38401 aataataata gtaaaatgga gtataaaatt aaaggagaca aaaatgacat attagaaata
    38461 gaattaggga aagagttaaa accaaatgaa agaatgtcat tagatataaa atataacgta
    38521 aaaataccaa attcaattgg aagatttgga tatggagaaa atactataaa tgttactaat
    38581 tggtttccta tagcttgtgt aaatgatgaa aggggatgga atttaaagag ttatgaaact
    38641 attggcgacc cattttatag tgagactagc gattttcatg tgaaactatt gattccaaat
    38701 aaatataaaa ttgctcatac aggaaaactt attgatgata aacatgataa taagaaaatg
    38761 ctatatgaaa tagaagctga aaacgttaga gattttgcat ttatactaag tagtaaattt
    38821 gatgtaaaca aagtagattc aaagggagta gctatcaata catataattt aaataaaaag
    38881 ctttctaaaa aagcaactga agtggcaaaa gattcaataa atatatttag tgaattattt
    38941 ggaaagtatc cttacaaaga attttctgtt gtagcaagtg acttttttat aggggggatg
    39001 gaatacccta tgcttgttat gatagaccaa agtttatata atgaaaaaaa tgaattttta
    39061 ctagaatatg ttattgccca tgagacagca catcaatggt ggtattctgc tgttggaaat
    39121 gatgaaataa gtgaaccctg gttagatgaa gcacttactg aatattctac aatagtttat
    39181 tttgaacaaa agtatggtaa agatatggca aacaagctta taaaaactat ggagatacag
    39241 acaaaaagtt atttgagtga aaatatattt aagccagcaa atgagtataa aaattctact
    39301 gaatacagct tgaatgttta tacaaaaggc gcaatagcat ttaatgaaat aagaaaagaa
    39361 gttggagata aagtattctt tgagacttta aatgagtact ataataaata taagcataaa
    39421 aatgctaatg gaagagcttt tgtggaacta tggaatagta aaggtgtaga tataaataag
    39481 attataagtg aatgtaagta aatagtgaat gtaagtaaat tttgtgcaga gtattaaatt
    39541 ttatttaata ctctgttttt ttggtataat ataatttata aggcagaaaa agaggtgaag
    39601 gaatgctaaa gtattgttca gtagggagtg gtagtagtgg taattgccac tatatagggt
    39661 ataaaaatac taatatacta gtagatgcag gattaagtgg caagagaata actacaggtc
    39721 ttaaagacat tggtgtagat gcagataaat taaaaggaat atttataaca catgagcatg
    39781 ttgaccatat aaaaggagca ggtatattat caagaaagtt tgatatacca gtatttgcta
    39841 atataaaaac atggtgttct atgaaggaca aattaggtga catcaaagat aaaaatatga
    39901 aagtatttga aaatgataaa acctactcat taggtgatat catagtaaga cctttttcaa
    39961 tagaacatga tgcgtctgac ccagttggat ataattttta tacagagagt gatgaaaaaa
    40021 tgtctatagc tactgatata ggatgtataa ctcaaaatat aaaaaaacat ctatataaat
    40081 ctaaattagt agtattggaa tcaaattatg accctaatat gcttatgatg ggttcatata
    40141 catatgcttt aaagaaaaga gtaatgtcaa gtactggtca tttatccaat gaagatgcag
    40201 ctaatttctg cgttgaactt attaatgaag gtacagaatc tatattatta gcacatttaa
    40261 gcaaagaaaa taattttcct gagttagcgt atgagacttc aaaaggagta ttagcatcaa
    40321 atgatatagt agttggacaa gatgtaaaac tagatgtact atcacgaaat gatgtttcta
    40381 atgtttatga gatgaagtag aggtgaataa ctttgctaaa gagaaatttt gaaaatgttg
    40441 aggataataa aattttatac tctataaagc agggtatgat tttagcgata cctgctatta
    40501 tgactggttc aactgctctt gtaattttga atcttccaat aaaggcttat caagaatatt
    40561 tatcaggctt gtttaatgga gaggttacaa atattcttaa ctttataaat gattctactt
    40621 taggaattat ttcattaata atattattaa caataagcta tagttatgga aaaatatatg
    40681 ggagcaagta tacagtactt gttcctatag ttgcaatgtg ctctttttta gtattttcac
    40741 atggtaatga gcttaattct tatatagaaa tatttaaaac aaagtggtta tttacatcta
    40801 taattgtttc tatgacatct tctgtattgt ttgtaaaact tacagaatct tttgttacaa
    40861 gtgtaaagtt tcatacagaa ggggctgatg cagactttaa tatggtagtt tcggctatag
    40921 ttcctttcat aatagtagta tttttgtttt ctatttttag agtggtaatg ataagtctaa
    40981 ttggcagttc aaactttcaa gatatatttt ataatttatt ttcaaatgtt tttaataaaa
    41041 tgggaacaaa ccttatgagt gctctgttgt ttattttttt aatgcacttt atgtggtttt
    41101 ttgggattca tggtagtaat gtattagata ccgtcgcaaa aaatttattt gaaaatagta
    41161 tggcaattaa cataaattta gttaataata atcaattacc aacagaaatt tttactaaga
    41221 ccttttttga tacaatggtt ttattgggag gatgtggctc tttactatgt ttagtaattg
    41281 caatttttct tagtgaaaaa cgtataaatg taagaaagtt agctaaaatt gcttcaatac
    41341 cagctctttt taatatcaat gagatgctag ttttcgggat accaattgtt tttaactata
    41401 ttatgtttgt accttttgta attactccta taatcttaac cgttacaagt tatgtggcta
    41461 tgtctacagg tattgtacca tgtacagttt cagctgtaga atggacctca cctatatttt
    41521 taagtggata tatgtctaca ggttcaataa gaggtagttt gttgcaagta tttaatttat
    41581 gtgttggtgt tatgatttat attccgttta taaaaatgtc gcaaaataga tatacatata
    41641 tgtttaaaaa taatatagaa aatttaacaa acttattaaa aaggtatgaa ttaacaggtg
    41701 aacagcctaa tcttctaaac cataatggta aaataggttc aatttcaaaa atgttggcat
    41761 cagacttgaa gtttgctatg aaaagaggag aaatagagct tttttatcaa ccacaagtca
    41821 attataatgg aaatgttgtg ggagcagagg gattacttag atggaaacat tcaataggag
    41881 ggttcattta tccaccacta gttataattt tggctaaaga agaagggttc ttagatgagc
    41941 ttggagagta tattattaat aaagcatgta ttgatttaaa gaagagtgaa aagctattga
    42001 gaaatcctgt taagttctct gtaaatatat ctccagacca acttgatgac cctaagttac
    42061 cagagcaaat aaaaaatatc attagtagta atgatataaa tcctaatatg ttaggtatag
    42121 aaataacaga gcaaattgca ttatcaggtt cacaaataat tattgaacgt atcaatgcga
    42181 tacataactt gggaataaag ttaattatgg atgattttgg gatggggcat agctctctta
    42241 tatatcttca aaataataac tttgatatag ttaaattgga tggttcatta gttaaagaga
    42301 tacttacaaa taaaagaagt agtgaaatta taatgactat tgtaaatctt tcaaaaaatt
    42361 tagattttga tatagttgtt gagtatgttg aaaatataga ccaaagggat aagttatatg
    42421 gtttaggatg tgaaatatat caaggatatt attatagcaa agcaatacct tttgaagagt
    42481 ttgtagaata tgcaaatcaa gaaagagaga tataatttta taagagcttg taaattctag
    42541 taatgcatag atttgtaata aaattaagtt taggagaaat atatgaatat aagtatagta
    42601 gtagtaggta aaattaaaga aaaatattta aaattaggta ttgatgagtt taagaaaagg
    42661 ctttctaagt attgtaagtt agaaattata gagttggatg atgaaaaagc tccagagaat
    42721 ttgagtgtta aggaaatgga aattataaaa gacaaagaag gaaagaaaat tttagggaag
    42781 ataaagcata atagttatgt tatagccttg gctattgatg gtaagggttt atcctctgaa
    42841 gagcttgcta agactatgag tgatttagca gttagaggta atagtagtct ctgttttata
    42901 ataggaggtt ctttagggct ttctgatgag gttttaggaa gggctgatta taggttatcc
    42961 ttttctaaga tgacttttcc tcatcagatg atgagattga tattgttaga acagatttat
    43021 agggcttata ggataaataa tggagaaccg tatcataaat aaatgatacg gtttttgtta
    43081 atttgacact taataatatt aaaataacaa aaaagtattg aaagtatatt gcatttaagg
    43141 tagaattaaa taaaatatta taacattata atgtttatat ggttgttaat aaaaatttgg
    43201 aggaaaatat atgataaaaa taatgttggc ctgttcagca ggaatgtcta caagtttatt
    43261 agttactaaa atggaaagtg cagctaaaga aaatggtata gagtcgcaaa tttgggcaat
    43321 accagaatca actatacaaa atgaaataga aaaatgtgat gtattattac taggaccaca
    43381 agttagatat gtattaccta aggctcaaga aattgctaag ccatataata taccagtaga
    43441 agttataaat atgatgcact atggaacagt taatggagaa gctgttttaa atagagcgat
    43501 agaacttaac aacactaagt aatataaatt ataatgtatt tttaatatat aaattgggag
    43561 aatcaaagga tggatgaaaa gactatagaa atatctttta atataatagg ttatgcaggt
    43621 gaaggtaaag gattagcttt tgaagcaata aaagaggcta agaatggaaa tatagaaaaa
    43681 gcaaaagaat tattaaaaga gtccagggaa gttataaata aagcacatag atatcaaaca
    43741 gaattaatac aaaacgaagc tagtggaaac aggactgaaa taagtgtcat acttatacat
    43801 gcacaggacc acttaatgaa tggcatgaat tttcaacagt tagctgagga aatcgttgat
    43861 ttacatttga aattacaaga taaataaaaa ttaaagataa taaattaaga gagttcttaa
    43921 aagatacatt atgtgtagca cactaattgt tagattattg attcaatatt tagtgagtaa
    43981 tacattagga ttattttgag gactcttttt atatttagtt taaagttaat aaatatttat
    44041 tattaataat ataagattat atgttataat attataacat ataatttaag aggtgaatca
    44101 tgttaagaaa tcaaccatta tatatacaag ttgtagatat attaaagcaa aaaatattaa
    44161 ataacgaata taaaattgat gaaaatattc caacagaaag ggagttagag caagagtttg
    44221 gagtcagtaa aattactatt agaaaagcta ttgagatatt agaatcagaa gggtatgtag
    44281 agaaaaaaag tggaaaaggg acaaaagtaa taagtaatag tctttttaat aagctatcaa
    44341 aagcagagtc tttttcaagt atacttttat ctaaaggtca taagttatct aaaaagacta
    44401 tttcaattga aaaaataata aatgatacaa attcacaagt atttagtata tttggagaaa
    44461 aatgtagcaa gattactaga atgtattact tagatagtaa gccatatata ttttttactc
    44521 attatattcc ttttgatgaa aatctaactg ttgaaagttt taataatgaa agttctttat
    44581 atatgtactt atataggaga aatataaata taactagatt tgaagatgaa ttttttatag
    44641 aagaatcaga actagaggta tcaaaggctc taaatctagc taaagacata ttattaggaa
    44701 gaaaaagaaa gacctatgat gagaatgata atatagttga gctatcattt gcaagatata
    44761 atacagaagt acaaaactat gtaattaaat acgaaatata ataagaatcc tgagtttatt
    44821 gaaatgataa tatgctcagg atttttgttt agttgtaaaa ataaaaaata ttataacatt
    44881 ataatgttta caactaaaca ttataatgtt ataatatttt taataaacaa gtgatattat
    44941 caattacata aaaattagtt tatgttatga aatcgttatt gcattataaa taaaggataa
    45001 tatcaataat acagggggat aactatggaa aaattcgcaa gttttttaga gcgcaagatt
    45061 atgcctgtag cagcgaagat aagtaatcag agacatatga gagctgtaag agcaggtata
    45121 atagcaacat taccactaac aatagtgggg tcatttttca caatattatt aaacatacct
    45181 attgatgctt atatggattt tatagctcca tttaaagcaa tattagatat accatttaga
    45241 tatactgtag gatttttatc tctatatgct acttttggga tagcatcatc acttgctaaa
    45301 agctacgatt tagatacaac aggtgttggt atgcttgcag ttatggcatt tttagtttct
    45361 acaatagttc caactcaagt agttgaacca gtaggtggag ttatagaagc tggtagatgg
    45421 atggatatgg caaaacttaa ttcgccatca ttatttggag ctatcgtaac atcattaatt
    45481 acagttgaaa tatatcgttt tatgaaggaa aagaatatta caattaagat gccagcagga
    45541 gttccagtag aggtttcaaa ttcatttact gcattattac cgacagcagt aattttaatg
    45601 ttattctggg taataagaca tattttagga tttgatataa gtgttgcact aagcgctatg
    45661 ttatcacctt taaaaggatt cttatcagga aatagtttag gtggtgggtt actgacagta
    45721 ttcctaataa ctttattctg ggtacttgga atacatggtc cagctataat ggggccagta
    45781 ataagaccta tatgggacat gtctatagca gaaaatataa ctgcattcac agaaggagta
    45841 tcagctcatg caatgccaaa catatttaca gaacaatttt tacagtggta tgtatggata
    45901 gggggagcag gggctactct tgcattagtt gtaatgttta tgttttctaa gtcacaatat
    45961 ctaaaaagtt taggtagatt aggattttta ccagggttat tcaacataaa tgaacctata
    46021 atatttggag caccaatagt tatgaatcca atactaggga taccatttat aattggacct
    46081 ataataatga caattctatc atatgttctt actattacag gggttatacc tatgatggta
    46141 gcaagattac catttgcaat gccagcacca atagcagcag taatgagtac taactggagt
    46201 atattagcag gtatcttagt attaatcaac tttgtgatat catttgctgt ttattatcca
    46261 ttcttcaaag tttttgaaaa acaacaatta caaagagaac aagaagaaat gagtgaaaat
    46321 ttataaaaat acatagatat agaggttttg tactatataa aatatagaaa aaacttataa
    46381 gttattaagg gtgaaggtag gaggaatgac ctttgccttt aattttatat attttaaata
    46441 atgtaatttg aggaggagaa agatggaaag aagattagga atatcagtat atccagagca
    46501 tagtaacatg gaagatgata aggcatatat aaaaatggct tcaaaatacg gatttaaaag
    46561 aatatttatg tgcatgcttt caattacaag acctaaggaa gaagttaaaa aacattttaa
    46621 agagattata acctatgcaa gagaattagg atttgaagta atccttgata tagctccaaa
    46681 catatttgat atattacaaa tatcttatga tgatttaaca ttttttagtg agttaaatgc
    46741 tagtggaata aggcttgact atggatatga tggaagtaaa gaagctatga tttctttcaa
    46801 tccatatgat ttaaaagtgg aactaaatat gagtaatgat gtagcatact tggataatat
    46861 aattacttac aagccaaatg taaataatat atatggttgt cacaattttt atcctcaaag
    46921 gggtacaggc ttgccatatg atttttttgt aagatgttca aatagattta aaaagtatgg
    46981 aataagaact gctgcttttg ttaattcaaa atatgcaaca atcggacctt ggaatataaa
    47041 tgatggactg tgtacgcttg aaatgcatag aaacttagat attgctacag caactaagca
    47101 cttattcgca acaggattga ttgacgatgt aattgtaggg aatgcatatg caagtgaaga
    47161 tgaattaaaa agaatgtctg aagtaaataa atatcaagtt gtatttaatg tagtaactga
    47221 ggaaaaaact tctgaagtag aaaagacaat aatggcaaat gagcaacact ttagaagagg
    47281 ggatataacc aaccaagtag caaggtctac agaagtaaga aaaaaatatg ctaaagaaaa
    47341 tttccctaag catgataata cgaccatctt taaaagagga gatgtagtga ttggtaatga
    47401 tgactttgga aagtataaag gggaattaca gttgatactt caagattgtg cagatgaaag
    47461 aaaaaataag gtaggtagaa taaaggaaga cgaaataatg cttttagact ttattgaacc
    47521 ttggagtaaa tttaaactta ttttagaggg agagtaaagt gaagatagac atattaataa
    47581 aaggtggaaa aacagtagat aaaagtataa ttgatatagc tatattagac gataaaataa
    47641 tagaagtaaa aaatcagata gatgattcta agtatcaggc aaatcaaatt ataaacctag
    47701 atggagaaaa atttattagt gctggttgga tagatataca tacgcattgc tacgaaagac
    47761 tagaccttta taaggattat ccagatgagg ttggaataaa aagcggtgtt actactgtag
    47821 tagatgcagg aacaacagga gctttagata taggtaaatt ttatgaagat actaaaaaat
    47881 ataaaacaaa tgtatatgct ttaataaata ttgctaagca gggaataaca tctcaagatg
    47941 aactttcaag tatgatgaat attgatgaat atgaacttaa aagagcagtt aaaaaataca
    48001 aagattttgt tgttggaatc aaagctagaa tgagtaaaag tgttgtaatt tcaaatgatg
    48061 ttgaaccttt aaaagtagct aaaagaataa aaaatgaact taatctacct atgatggttc
    48121 actttgggag ttctcctcca acgatagagg atatatttga ctatatggaa aaaggagata
    48181 tattaaccca tatatataat ggaaagccaa atggaatact tagaggcaat gaggttaaaa
    48241 aagaaatcat agaagctaga gaaagaggta taatccttga tgtaggtcat ggaaccgaaa
    48301 gttttagtat ggatattgca atgaaatcta aggatgcagg aatttttcca gacactataa
    48361 gtacagatat atatattaaa aatagaataa atggtccagt gtataatcta tctacaacaa
    48421 tggaaaagtt tatatatatg ggctattcac ttgaagatat aatagataaa gttactaaaa
    48481 atgcagcaga tgcaataagt ttaaaaaata aaggtttaat aaaagaagga tatgatgctg
    48541 atttaactat atttgatgtg gttaatgaag aaaaagaact tcaagattct ttgaataagt
    48601 cagtaatcac aagtacgtct ataaagccaa gagcagtagt agtcaatgga gaatatttaa
    48661 atataggtaa gtctatagga gagaatgagt agaagggaga aactattgta tgagtagtat
    48721 atttgaaaaa tactctgtaa gacgtgttat aaatgcttca ggcaaaatga ctatactagg
    48781 agtatcaaca gtagataagg aagttattga agcaataggt gaagggtgta aaaatttctt
    48841 tataatagaa gaacttataa ataaaacagg tgaatatata gcaaatttat tagggtgtga
    48901 aagtgcacta atagtttcta gtgcatctgc tgggattgca cagagtgtgg gagcaatgat
    48961 agcaaaagat gatatgagtc tagtttacaa tgtaaataat cctaagaaac aagttaaaag
    49021 ggaaataata attccaaagg ggcataatgt tgattatgga gttccagtag aagtaatgat
    49081 aagacttgga ggaggagaag ttgttgaggc cggctatgct aatatgtgta acaaggaaca
    49141 tataataaga gagataaatg aaaatacagc agcaattatg tatattaaat ctcatcattg
    49201 tgttcaaaag agtatgctaa gtgtattaga tgcagtacaa gttgctaaag aatataattt
    49261 acctttgata gtagatgcag cagcagaaga agatttaaat gtatattatg aattgggagc
    49321 agacctagtg atatacagtg gtgctaaggc tatagagggt cctagctcag ggttagtaat
    49381 aggtaagaaa aaatacatag ataatgtaaa gcttcaatca aagggtatag gaagagctat
    49441 gaaaatagga aaagaaaata ttgtaggtct aacatgtgca attgagagat atataagtaa
    49501 tgataaagta actttaaaag aaatggagga caagctaaat ccatttatag acaagataaa
    49561 tactataaag ggagtgagtg ctagtataac tagagattca gcaggtagag aaatacttcg
    49621 tggagaaatt gactttaatg aagatataat aaataagtca acacaacaaa ttataaatga
    49681 acttagaagt ggagagatag ctatatacac tagagactat aaggctaatg aaggcaagat
    49741 tgagattgat ataagaagtg taactggaag tgatttagat actatttata ataggataaa
    49801 aaatatagta gaaagttaga gtgtagagta agtgacatta taatgattta ataaattaaa
    49861 ttttaccaat ggaggggata aatatgaatt gtataccaca atattataaa aatagagttt
    49921 gtttaaatgt tcttgcagga agcataaaaa atgctaaaga agtatatgat gcttgtgatg
    49981 ggtatgtatt gataggagta ctatcaaaga attacagtac tgtagaagca gctattgaag
    50041 atatgaaaaa atactcaaag gaaatagata atgcaatatc tgtggggctt ggagctggag
    50101 acccaaatca gtcaaatatg gtatctcaga tttctaaaga acttcagcca caacatataa
    50161 atcaagtgtt tacaggtgtg gctacgtcta gagcattgct tggtcaaaat gatagtataa
    50221 taaatggatt agtttctcca actggtaaac caggatttgt aaaaatatcc acaggtccat
    50281 taagttcaaa agaaaaagat ggtatagttc ctatagaaac agcaatagct atgatgaaag
    50341 atatgggagg aagctcaatt aagttttttc caatgggagg gcttaaaaca aaggatgaat
    50401 atatagaagt tgcaaaagct tgtgcaaagc ataattttta tttagaacca acagggggta
    50461 tagacttaga taacttcaaa gagatagttc aaattgcact tgatgctggt gtagaaaaag
    50521 ttatacctca tgtttataca tcaataattg ataaagaaac aggtgaaacg aaagtggaag
    50581 atataggagt actttataaa ataatgaaag aattattggg atagatttat gaatatatta
    50641 gcttttggtg aaataatgat gagactttca gtacctgact acaagttctt aacacaaacc
    50701 aatgaactaa attatataat tacaggcaca ggattaaata tattatctgg acttaaaaac
    50761 tttggataca atacctatat gttgacaaag ttgcctaata ataatgtagg taaagcatca
    50821 agtgcaaata taagaaagct tggagtaaaa gatgacttta tcacatatgg agggaatcat
    50881 ataggagtgt attttcttga aaatgggtat ggagaaagac cttctgaagt gacttatttg
    50941 aataggttaa atagttcatt ttgtgagagt aaattacaag attatgatat tgataaatgt
    51001 ttagaagaaa tggatatagt ccttatttgt ggtattgcta tgcaacttac agattcaatt
    51061 aaagagattg ctttagaact agctagaaaa tcttatgaaa aggggataaa agtattcttt
    51121 gattttaatt ttagacaatc attaaatcca gaaaggactt atgatgattt agtaaatgat
    51181 tataagaaaa tactaccata ttgtcatggt ctatttgcta gttatagaga tataaataag
    51241 atacttaata tagatagtct aaatataaaa tctagttcag aattgattaa aaaagagtat
    51301 gatataggta ttgtagctgg aactatgaga agatttgatg atatgaataa tagatttata
    51361 aagggatata tatcaaatga tgatggttat tttgaaagta gggagtataa gttagaaata
    51421 tatgacaggg ttggtgccgg agatggatat gtagcaggaa ttatatattc atatttggaa
    51481 aatatgaaga gtgaagatat agttgagttt ggggttgcta gttcggtgtt agctcataca
    51541 acttatgggg ataattcttt agtaagcaca ggtcatgtac ttagacttat gaacaatgaa
    51601 aaaatagata tattgagata atacatttgt atataataaa atttttatct tttttagaca
    51661 cacttttgac ttgtttatat ttgttaaaca gagttatttt taatgattat aaatattaaa
    51721 ttaaaagtta aataataaaa tagtagaaaa tagcattaac tatagaaaaa atggttaatg
    51781 ctatttttat cgttaatatt gattaatttt atattataga aatgaacttt tctaatgctg
    51841 gatttgtatt ttttttattc catacaacta caacttcaat tctattttct acttctttta
    51901 taggtactat tgcaatatca cgttctatca ttgtatctgt aacacaaaat gaaggtaaaa
    51961 tggatattcc catgttagaa gataccaatg attcaatagt attaagatta tttgaacgtt
    52021 gtaccacatt aggtacaaac cctgcttcac gatatctatt ctgtatcatt gacttttgtc
    52081 catactcatc ccctgtttct tttacaaaaa taaatttatc atgttgtaat tcaattaaat
    52141 cgatagaatc ctcattgtaa agtggatgac caggaggtaa aagagctacc aaagaatatc
    52201 tttctacagt tttatattca aaatctttta atggttgatt ttctggatta ataacaaaag
    52261 cgaggtccat agaattattt tttactaagt ttaaaagttc ggttatttca ttagtacaaa
    52321 tatccataga tatattaggg tatgtattag aaaattcttt taaatattgt tgaagtttgt
    52381 ttttttcata tcctattaag gttccaatgc tcaaagttcc aaaaaaacca tgtgcaaatt
    52441 gttgtgtttt tgcaatagca tcattgatat tttttattat agtacgtgcc tcagataaaa
    52501 aaacttttcc agctggtgtt agttcaacat gacgtttact tcttgtaaat agagttacat
    52561 ttatttgttc ttctaaagct tttatttgct gtgtaacagc agtttgagaa atataaaatt
    52621 tttctgctgt tttggtaaaa cttaaatttt ctgctacaga tataaaatat tctaattgtt
    52681 tagtattcaa ataatcaccc ctatttaaac ttgattgttt gtaaacctta tttatctata
    52741 attaaagctt attatagtat aagaaaattt acttttaaag aatattagaa aata
//
LOCUS       DAJMZY010000017        51929 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.017, whole genome shotgun sequence.
ACCESSION   DAJMZY010000017 DAJMZY010000000
VERSION     DAJMZY010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 51929)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51929)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51929
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.017"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            27..101
                     /locus_tag="OE968_000950"
     tRNA            27..101
                     /locus_tag="OE968_000950"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:59..61,aa:Thr,seq:tgt)
     gene            116..200
                     /locus_tag="OE968_000951"
     tRNA            116..200
                     /locus_tag="OE968_000951"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:150..152,aa:Tyr,seq:gta)
     gene            210..293
                     /locus_tag="OE968_000952"
     tRNA            210..293
                     /locus_tag="OE968_000952"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:244..246,aa:Leu,seq:tag)
     gene            317..391
                     /locus_tag="OE968_000953"
     tRNA            317..391
                     /locus_tag="OE968_000953"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:349..351,aa:Gly,seq:gcc)
     gene            416..492
                     /locus_tag="OE968_000954"
     tRNA            416..492
                     /locus_tag="OE968_000954"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:450..452,aa:Arg,seq:tct)
     gene            502..577
                     /locus_tag="OE968_000955"
     tRNA            502..577
                     /locus_tag="OE968_000955"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:535..537,aa:Gln,seq:ttg)
     gene            586..661
                     /locus_tag="OE968_000956"
     tRNA            586..661
                     /locus_tag="OE968_000956"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:619..621,aa:Lys,seq:ttt)
     gene            664..752
                     /locus_tag="OE968_000957"
     tRNA            664..752
                     /locus_tag="OE968_000957"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:698..700,aa:Ser,seq:tga)
     gene            756..831
                     /locus_tag="OE968_000958"
     tRNA            756..831
                     /locus_tag="OE968_000958"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:789..791,aa:Phe,seq:gaa)
     gene            838..911
                     /locus_tag="OE968_000959"
     tRNA            838..911
                     /locus_tag="OE968_000959"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:872..874,aa:Met,seq:cat)
     gene            926..1002
                     /locus_tag="OE968_000960"
     tRNA            926..1002
                     /locus_tag="OE968_000960"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:960..962,aa:Ile,seq:cat)
     gene            1020..1096
                     /locus_tag="OE968_000961"
     tRNA            1020..1096
                     /locus_tag="OE968_000961"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1054..1056,aa:His,seq:gtg)
     gene            1105..1180
                     /locus_tag="OE968_000962"
     tRNA            1105..1180
                     /locus_tag="OE968_000962"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1138..1140,aa:Lys,seq:ttt)
     gene            1188..1261
                     /locus_tag="OE968_000963"
     tRNA            1188..1261
                     /locus_tag="OE968_000963"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1220..1222,aa:Cys,seq:gca)
     gene            1269..1345
                     /locus_tag="OE968_000964"
     tRNA            1269..1345
                     /locus_tag="OE968_000964"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1303..1305,aa:Arg,seq:acg)
     gene            1358..1433
                     /locus_tag="OE968_000965"
     tRNA            1358..1433
                     /locus_tag="OE968_000965"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1391..1393,aa:Val,seq:tac)
     gene            1509..1922
                     /locus_tag="OE968_000966"
     CDS             1509..1922
                     /locus_tag="OE968_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218259.1"
                     /translation="MYIVIGNEIVDSEELKIIIDKNSEFKVEKDLSKSTKREDVIAYQ
                     LSIDLNYLDSLINEQCNLASLSDEEKFDEYMTLSDELALDLEELMPKYTIINARAYKL
                     DEVDGIVKIILAVAYADLGHLKLSDVVKRLSRQVD"
     gene            2231..5662
                     /locus_tag="OE968_000967"
     CDS             2231..5662
                     /locus_tag="OE968_000967"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HCP7218260.1"
                     /translation="MLKKFNKILVANRGEIAIRIFRACSELGIKSVGIYSKEDKYGLF
                     RTKADESYLIGEGKGPIDAYLDMDGIIDLAKRKKVDAIHPGYGFLAENAEFARKCEEN
                     GITFIGPSSKVMNMMGDKINSKKIAKEVNVQTIPGVEKAIRSTEEAKEVANKIGYPVM
                     IKASNGGGGRGMRIVHREEDLELEYETACSESRKAFGEDIIFIEKYIADPKHIEVQIL
                     GDNYGNIVHLYERDCSVQRRHQKIIEYAPAFSLDDKVRKEICEDAVKLSKHVGYSNAG
                     TLEFLVDANGGHYFIEMNTRVQVEHTVTEMVTGIDIVQSQILIAQGYSLDSEEINIKS
                     QDDVEIRGYSIQCRITTEDPKNKFMPDTGKIQVYRTGSGFGIRLDGGNGFTGANISPH
                     YDSLLVKTISWDRTFQGAINKTIRSIKELRVRGVKTNVGFLVNVLNNPIFSNGKCSTK
                     FIDENPDLFEITESKDRGTKLLQFIGDVIVNDNACKEKPLFDALHDPRMDKDGSKSEG
                     SKILFDKLGKSAYIEKIKNDKKLLLTDTTMRDAHQSLLATRIRTYDLLKAAKPTEKYQ
                     KDLFSLEMWGGATYDVAYRFLKESPWRRLQKLREEIPSIMFQMLLRASNGVGYKNYPD
                     NVIEEFTKESARQGIDVFRIFDSLNWVENMKPSINTALETGKIVEATMCYTGDILDKT
                     KTKYNLEYYIKMAQELESLGADIIAIKDMSGLLKPYSAYTLVKELKKNVKAPIHLHTH
                     DTSGNGVATCLMASEAGVDIIDAALESMAGLTSQPSLNAIVEALKNTERDTGIDLFGY
                     DELGKYYKDLRKVYNKFESDLTNSCAEIYNFEIPGGQYTNLKPQADSLGLVNRFDEVK
                     EKYKEANEVVGDIIKVTPSSKVVGDLAIFMTKNKLDKDNIIEEGKNLSFPDSVVDYCK
                     GMIGQPEGGIPKDLQEVVLKGEEAITVRPGSLLPAEDFDEIAKYLNEKYDINANIRNV
                     ISYALYPKVYEDYIKHLQHYNDISKLESDVFFYGLNKNEECEVEIEEGKVLTIRLVEI
                     GEVKENGFRTIGFELNGMVREVEIKDKNFSGKINNVEKADMNDPLQIGASIPGKVIKI
                     MVKEEDEVKANQPLIVIEAMKMETIIVAKTDGVIKSIKVKEDDMVEDKQLLMIMK"
     gene            5904..7832
                     /locus_tag="OE968_000968"
     CDS             5904..7832
                     /locus_tag="OE968_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HCP7218261.1"
                     /translation="MKVYDSKMLRNVAVLGHSGCGKTNLIETIAYTANTNKIPKLTDK
                     VNMTYSMGLIPIEYNDYKFNLLDTPGYFDFSGDVVSSLRASDAAIIVIDATAPIQVGT
                     EKSLELTESIPKIMFINKIDNEKARYKDAIAMLREKYNNKIVPMISPIYKDKNFVKLH
                     NVFENIDDLEGEFKEQAMSVKEALMELIAETDDQILDKYFNGEELTTEEIQKGIIIGI
                     QRGDIIPVICGSTINNIGTKEILDTISSYLEPIFTEESKPFRGLVFKTMVDPFVGKMS
                     YIKITEGVLSKDKDVFNINKNVKEKIANIYTLRNSELVEIEKAKAGDIVVITKVNSLK
                     TGDTISADKDAEALEKIDFPKPQIYYAVTPKNKGDEEKVASVLNKLVEEDPTLHWYRN
                     TETKQALLGGQGELHIKTIKNKMKDKFGVDVELNDLKVPYRETIKGTADVQGKHKKQS
                     GGHGQYGDVKIRFERCESDFEFTEEIFGGSVPKQYIPAVEKGLKDSMQKGILAGYPVT
                     NIKATLYDGSYHDVDSSEMAFKMAASAAFKKGMEEAHPILLEPIMKLKITVPEEYMGD
                     VMGDINKRRGKIFGMEPDDKGKQIIFAEAPQAETFKYAIDLRAMTQGRGYFEMELERY
                     GEVPSQFAEKIIGLATAK"
     gene            8285..8749
                     /locus_tag="OE968_000969"
     CDS             8285..8749
                     /locus_tag="OE968_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HCP7218262.1"
                     /translation="MATMTDIIEKFIKDLMEEDNSIQIQRNELANLFSCAPSQINYVL
                     TTRFTIDRGYYIESKKGGGGYVQIEKIRKSKDGHIRELLNEKIGSQISYKKAKELLEG
                     LKESDLINERELKLILYAIDDKSLCMPIYELKEKVRSNILKNIIIGLFSIEE"
     gene            8756..9250
                     /locus_tag="OE968_000970"
     CDS             8756..9250
                     /locus_tag="OE968_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UvrB/UvrC motif-containing protein"
                     /protein_id="HCP7218263.1"
                     /translation="MLCQKCNKNKASVYYNKIVNGEKTEMYLCSECAKENTEMNFNLD
                     MPFSMMDIFSNLGFQPKKELEEKLVCPKCNTTYSEFKNNGRFGCSECYNAFSSQVNPM
                     LQNIHGHIEHTGKAPKKSFYKISVENEIKELKEDLDRAIKNEEYELAAQFRDKIKYLK
                     GSID"
     gene            9266..10291
                     /locus_tag="OE968_000971"
     CDS             9266..10291
                     /locus_tag="OE968_000971"
                     /EC_number="2.7.14.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein arginine kinase"
                     /protein_id="HCP7218264.1"
                     /translation="MKENIVMKSRVRLARNLNNYPFPNKLDKECAMEIIEKVKNAFIN
                     SNLEQKEEFDFYKIEDLDQSKKMLMVEEHIISPDLAENDKSAVIVKKDKTISIMINEE
                     DHIRIQTICDDLNLEYAYSVANEIDDLLESSLEYAFNTKLGYLTSCPTNTGTGMRASV
                     MMHLPALSQLGYMDELYKISSQIGIAIRGIYGERTEALGNIYQISNQLTLGRTESNII
                     ENVSGLTKDAISKEIKAREILQKKLGIKLEDKIFRSIGTLENSRVMSSAEAMSHLSNI
                     KMGIEMNYIDKLDLRAIEQLMIGIQPAHQSIMYKSDDVENRDINRATYIRETLEKLRG
                     GMNCELQ"
     gene            10278..12725
                     /locus_tag="OE968_000972"
     CDS             10278..12725
                     /locus_tag="OE968_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HCP7218265.1"
                     /translation="MNFNRFTQRAKKAIDLAFESAKSLGHNIVGSEHILLGLLREEEG
                     IAAKVLSKVGFTEAYLEGKIVDMEGKGEEISEDIVLSPRSKQILELSGMFANKLKTNY
                     IGTEHILLAIIQEGEGIANKILNYAGVNDRTLAQLTIDMMGISDKNQYKAENSYTGNQ
                     NQAESKVLDKYGRNLTLYAKQNKIDPVIGREKEIQRVIQILSRRTKNNPVLIGDPGVG
                     KTAIAEGLATNIALGNVPETLKNKTLYSLEMGSLLAGAKYRGEFEERIKEVVDEVVKN
                     GNIILFIDEMHTIIGAGSTGEGSIDASNILKPALARGEIQVIGATTIDEYRKHVEKDS
                     ALERRFQPVMVDEPTKEDSIKILEGLRDKYEAHHKVKITDDAIKAAVELSTRYISDRY
                     LPDKAIDLIDEAASKVRLKENTPPSEIKKLELEIENIDKEKEEAVRCQDFEKAAKIRD
                     EQGLLKKQLEDVRERWNKSSKHSDLVDGEVIAEVVGLWTGIPVNKILEEEADRLLRLE
                     EILHNRVIGQEQAVKSISKAIRRSRAGLKDPNRPIGSFLFLGPTGVGKTELSKALAEV
                     QFGDENQIIRIDMSEYMEKHAVSRMIGSPPGYVGHDEGGQLTEKVRRNPYSVILFDEI
                     EKAHPDVFNILLQILDDGRLTDSKGRTVDFKNTIVIMTSNVGASTIGRQKTLGFSIAK
                     GDEEEKSQYEKMKENIMGELKQRFRPEFLNRIDDIIVFHSLNENHISKIVLLMAAKLQ
                     ERLKEMDIKLEMSDEAVKLISKSGFDLEYGARPLKRALQKELEDELSEAILKGNVKKG
                     SNVVAKVKDEKIVFETK"
     gene            12905..14278
                     /gene="radA"
                     /locus_tag="OE968_000973"
     CDS             12905..14278
                     /gene="radA"
                     /locus_tag="OE968_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HCP7218266.1"
                     /translation="MAKIKTKYVCQSCGYETAKWLGKCPECTKWNTFVEEIDQKSTKK
                     EVFIIDKSSSKPVSINSIESKEEERFTTDINELDRVLGGGIVKGSLVLVGGDPGIGKS
                     TLLIQVSSNVANLGKTVLYITGEESESQIKMRAKRLGINSENLYIFAENNLSIIESYL
                     ESVNPELIILDSIQTVFSPEISSAPGTVSQIKEGTSKFMKISKKMGISTFIVGHVTKE
                     GSLAGPKLLEHMVDTVLYFEGERYNTYRLVRAVKNRFGSTNELGVFEMRDLGLVELDN
                     PSKILISEKPKDVAGSVIISTVEGTRPMLLELQALVSPTSFGIPKRTSTGVDYNRVGM
                     LLAVLEKRVGLQIQNQDVYINIVGGIKINEPSIDLGIAISVASSFRNIPIDEDIAVTG
                     EVGLTGEVRAVSFIEKRIAECKKLGFKKIVVPRSNYDVVKETKGIEIWPVDNLRQAIN
                     IVLGRNQ"
     gene            14281..15351
                     /gene="disA"
                     /locus_tag="OE968_000974"
     CDS             14281..15351
                     /gene="disA"
                     /locus_tag="OE968_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA integrity scanning protein DisA"
                     /protein_id="HCP7218267.1"
                     /translation="MENFLDNKNMLYALKMISPGTPLRLGLNNVLRAKTGGLIVIATN
                     EDVMKIVDGGFAINAEYSPSYLYELAKMDGAIVLSGDVKKILFANAQLIPDYFIETSE
                     TGTRHRTAERVAKQTGAIVIGISQRRNVITVYRGNEKYVVEDISKIFTKANQAIQTLE
                     KYKTVLDQAVTNLNALEFNDLVTIYDVALVMQKMEMVMRVTSIIEKYVIELGDEGTLV
                     SMQLEELMGTTRIDQKLIFKDYNKENTEIKELMKKVKNLNSEELIELVNMAKLLGYSG
                     FSESMDMPIKTRGYRILSKIHRLPTAIIENLVNYFENFQQILDASIEELDEVEGIGEI
                     RATYIKNGLIKMKQLVLLDRHI"
     gene            15440..16534
                     /locus_tag="OE968_000975"
     CDS             15440..16534
                     /locus_tag="OE968_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HCP7218268.1"
                     /translation="MIRKVTRILFILLGFTIGITTYLTLMKDFEILTFGKETYGYIAA
                     VVAGIIIAILGYLIEPWVVNKVKEIAKIVDKELSKYPQTDILLGSMGLIVGFVIAYLL
                     SGLVNRIPIVGGILSLLLYLFLGYLGMKVALKSKNDLFNIGKLGRLANPIKDKDKDKE
                     NKKEVKAIPPKVLDTSVIIDGRIADICKTGFIEGKLIIPAFVLEELRHIADSSDDLKR
                     VRGRRGLDILNIIQKELNIEVEISERDFDDIAEVDSKLLKLAQVLNGKVVTNDYNLNK
                     VAQFQGVEVLNINELANAIKPVAIPGEDMVVQVVKEGKEAQQGVAYLDDGTMIVVDGG
                     RKYMNETIKVLVTSVLQTPAGRMIFAKPKN"
     gene            16663..18840
                     /locus_tag="OE968_000976"
     CDS             16663..18840
                     /locus_tag="OE968_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218269.1"
                     /translation="MRKKIISFLATFIIILTSASQYSFADDISTRGKVIFIDMNRTSM
                     SNMLRIKSLREELDNRGYIGLMNIRGDKGSDDRRSYASMGAGGRANVANEEDINFESS
                     SKDRNIVFESATGKSAKGINNLTINKSINENLNFGEYGSVLGSLGQSLSDNGLKASVL
                     GNSDIIENGQLIKNRNLCLTAMDEYGRIPNGNVDTINKKDLSMPYGISTDYDKLIVET
                     KETYKNNDVIFVELGDTYRLDLYKPNLNEKTYESMKDNIEKNIDIYLKNIFSMVEEND
                     TIYIASAFPSDLDYKNKRRLSPIIKLNGEGKGILSSSTTRREGIVTNLDVGVEILDNF
                     NIKNQNMVGRKYELINRDDNKEFLMDEYQKIVSISSIRSTILNGFVSIVFLSWIVAMI
                     AILFRKHISKNYKETTFFILKELLKIGIVMPLSFMITPIMNFKTPLAISLGIIIITLT
                     IYLISKVLIKNDLKNMLFFTGLTIVIMVIDAGFGSYLMKSNVMSYDCIIGARYYGVGN
                     EYQGVAIGSAIFTFAILLTYKNIPKWYIIVFSLVILITSASPIMGANVGSAISECVAF
                     LLFILLIYNVKIDFKKIVLLGIAVVFVLGVFVAIDMILGSNSHLGMFVKEIYFNGPGE
                     IIQTFSRKIEMNLKLAQTSAWVNILLTGIGVILVLMINQIRYFKQLMDEYPIVFKGFI
                     ASIAGCLVTLLVNDSGIVSSATAFIYVIVPMITLSINLTALKE"
     gene            complement(19026..19871)
                     /locus_tag="OE968_000977"
     CDS             complement(19026..19871)
                     /locus_tag="OE968_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCP7218270.1"
                     /translation="MNRNNFSHEIIEPIDNLDVNFKLFDDSGSYVANHWHNSLEIIYI
                     TSGDLQINMEGYTYNLKANECMFINSGIIHSTRCIYQNTSILLQVPLSFLNKYIPDFK
                     NCYFDFKVNANDNNYKKNSSKVKLILENMREIKLSSPPAANLLFTSLLFELLFELYTN
                     FKISVGNKNMKKTVLDLSKFEPVLEYTKINYKMPISINKIAKVAHLQPEYFCRKFKQY
                     MGQTYLEYLNDVRISHIYKDLINTNDTLCSILEAHGFTNTKLFYRIFKEKFKCTPKHI
                     RKKST"
     gene            20088..21254
                     /locus_tag="OE968_000978"
     CDS             20088..21254
                     /locus_tag="OE968_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulase family glycosylhydrolase"
                     /protein_id="HCP7218271.1"
                     /translation="MYIKGVNLGGWLVLEKWMTSSLFEGTEAEDEYYLPRQLSREAYE
                     SRIKTHRSEYITERDFATIKSMGFNSVRIPVPYFIFGDCEPFIGCVKELDKAFAWADK
                     YGLSILIDLHTVPGSQNGFDNGGISGICSWSQNPEYVAFTLNVLERLAKRYGMRHELY
                     GIQILNEPITERMWNIMNVPNRFKAVDKEMARGSKPNSLEFLRDFYIKAYRVMRPYMR
                     EENVIVFHDAFELKAWKDFMREEEFKNVVLDTHQYLMLAEADGCEQSIDSYLKYIREN
                     YAKDILQMQKYFPVICGEWSLFNSYVCGIDTNGGQSPLNGIESNIDKLSKDDKRELYR
                     KIAKAQLDAWRNGSGHYYWNYKLLLDTVNEEGWIGWDSWDLGKCVAQEWYPIEY"
     gene            21276..22922
                     /locus_tag="OE968_000979"
     CDS             21276..22922
                     /locus_tag="OE968_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HCP7218272.1"
                     /translation="MIKNPILPGFNPDPCICRKGDDYYLVVSSFEWFPGIPVYHSKDL
                     KNWELYTHILTDETKIDLKKLPSSKGIWAPCLTYCEEEDLFYIVYGIMNSMNARYFDV
                     DNYLITSKDIKGEWSEPVYLHSSGFDASIFHDDDGKKWIASLDWETREGYEKPGVICL
                     VEYCTKKKEIVGYPKRIWSGGTDRGCIEAPHITKRGDYYYIMCAEGGTGYGHSVTMGR
                     AKNIWGPYEKDSMNPIVTSIPGDFYERHDPDHLKPKYYNPESKLQKSGHGSYIETTSG
                     EVYLVHLTSRPFVPELRCTLGRETAIQKMKWTKDNWLRMEDESNLAKEYVSESKLEEH
                     LVSSIPSFDDFDSNELGLQYYAPRISPLSFADVKSRPGYVRIRGQESRTSLNKVSILA
                     RKLTSVYARITTKMEFYPEVHQHSAGLIMYYDNMNYINLRKYYSETLGQSALSIIHLE
                     NGEKTEFLNTRIPIKDIPIYLRLYIQGRKSYFEWSYDEKNYQRIGKVFDTTKFSDEYC
                     KYGEFTGTFIGLTCADRVKHKHYADFDFFEYIVDESKDVD"
     gene            23019..24392
                     /locus_tag="OE968_000980"
     CDS             23019..24392
                     /locus_tag="OE968_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCP7218273.1"
                     /translation="MNTEVNVKATTIRYEKISFFERISYGCGDLGCNIIYSAMSAFLL
                     FYYTNYADVSAAAVGSIMLVSRILDGFSDLTMGIIVDRTKSKYGKARPWILRMAIPFA
                     IAAVLLFSVPSNLGITSKLIYIFITYNLVSTVIYTAINVPYATLNSLITQNQYERGVL
                     SIFRMILATCGTLLINGLTLPLVEYFGNNLSAWTKTFFVFGIASIMVFFITFTGTKER
                     VKAVKQDRNEVIPFKIGIKSLFRNKYWIQITLCLVCIFIVFAINGGSSVYYAKFILGD
                     EKLFGPINMVSNISQIIAMFMVAPFIKKFGKRNVLIVGSIILISSNVMFIIVGQNHIG
                     VIFASAIKGIGSAGIASTMFAIVSDTIEYGEWKTGYRTEGLINSASSFGFKVGNGLGS
                     AILGAVLSIGGYVGTSATQSDLAIVSIKVCFIYLPIFITILQIIIMSFYKLDKEYSTI
                     LNELNTK"
     gene            24837..25790
                     /locus_tag="OE968_000981"
     CDS             24837..25790
                     /locus_tag="OE968_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HCP7218274.1"
                     /translation="MKKIGDLRLMMKCCSLYYEDNLNQQEIANQLGISRPTISRILKE
                     AFEQGIVKIQIVDVLKNDYQKIERSLERKYKLKEVIVVDDKQDALTQKQELARAVSEY
                     LTRVVKENDIIGVSIGTTLKEIPRYVEKSNCKNVTFIPLLGGIGDNEIDIHANQIAVS
                     LARAFGGDFKLLHAPAVMSDLSTKEKLCKDEKIKEVLDLIDKTTIAIVGIGNPMSLNS
                     TIMASGYMNEADIEDLKKYNSIGAICLQAFDKEGKTSILEFNQRVLGVKLEDLKKIKR
                     TIGVASGDEKIEAIKASLKAKFINSLAINHSLALKLLEDCD"
     gene            25828..26790
                     /locus_tag="OE968_000982"
     CDS             25828..26790
                     /locus_tag="OE968_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HCP7218275.1"
                     /translation="MSISKETLLEMYKRMNQARKFEEKVSWFFARGMVHGTTHLSVGQ
                     EASSVAAVMALEKGDLVSLTHRGHSQFIGMGIDLNKMMAELMGKETGFCKGKGGSMHI
                     ADIESGNLGANGVVGGGLTIAPGAALTQQYKKTGKIVLCSFGDGASNEGTFHEGINLS
                     SIWKLPIIFYCENNLYGMSTSIKRHMNIESIATRAASYGIEGISIDGYNPIEVYETVQ
                     KAAEKCRRGEGPVLIESRTYRWLGHSKSDANVYRTKEEIESWKAKDPIEFLKNYLIEN
                     NLSNEDELDKIQEFAKQSIEDAVEFAQNSPNPKIESLLEDVYAD"
     gene            26815..27801
                     /locus_tag="OE968_000983"
     CDS             26815..27801
                     /locus_tag="OE968_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HCP7218276.1"
                     /translation="MSTRELTYAQAIKEAMSEEMRRDENVIFMGEDIGIYGGAFGVSV
                     GMIDEFGPERVRDTPISEAAIAGAAAGAAATGLRPIMEVMFMDFVTISMDAIVNQAAK
                     MRYMFGGKAQVPMVVRCPGGSGTGSAEQHSQSLEAWFCHVPGVKVVAPSTPADAKGLL
                     KAAIRDNNPVIFVENKLLYRKKGFVPEDDYVIEIGKADIKREGTDVTVITYGRMLQSV
                     EEAAETLSKENINVEIIDLRTLYPLDKETIVKSVCKTGRVLICHEAAKTGGLGGEISA
                     LITESESFDYLDAPVKRICGKDVPIPYNPELEKAVVPRVDEIEEAIKSLIVR"
     gene            27814..28860
                     /locus_tag="OE968_000984"
     CDS             27814..28860
                     /locus_tag="OE968_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxo acid dehydrogenase subunit E2"
                     /protein_id="HCP7218277.1"
                     /translation="MVANKIKATPAARSQARKDNIKLDRLIGSGENGRIHLVDVLNYL
                     KDNKANTTPLARRIAEDLNIDLETIVGTGYNGKIRKCDVEKLTGKETIVSTNTSKSSE
                     KKELKIENENSRMFNTVEGIFEKPNPMRATVAKRMSESYFSAPVFTFNIEVDATELKV
                     LRAKLIDTVKESTGVKLTMTDLIVMAVSKILPNHQALNSAWTDEGIFRYKDVNIAIAV
                     GLDEGLYVPVVKNANKKSLKEIAKESKELAEKVKTGKLMPADQEGNTFTISNVGMYGI
                     TTFTPIINMPSSAILGVGATQDKFVPVNGEAKIKPIMNLSLTSDHRVIDGTVAAKFLK
                     DLKELLENPLSMLV"
     gene            29027..30757
                     /gene="lpdA"
                     /locus_tag="OE968_000985"
     CDS             29027..30757
                     /gene="lpdA"
                     /locus_tag="OE968_000985"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HCP7218278.1"
                     /translation="MSVEVIMPKAGVAMEEGTIVSWLKQEGEEVKIGEPILEITTDKV
                     NMEIESEGEGTLAVIIHKEEGEVLPVFTVIGVIAEKGENQEEVKAKYLSGNVSKEDIV
                     EENQNIEFKEEKINKKECNHDYDVVVIGGGPGGYLSALKAALLGGRVALVEENILGGT
                     CLNRGCIPTKTYIKTAEILEEIDQLSKRGVKVTVDKEQDIKKAIKYKNRVVKKLTAGV
                     GGLLKSRDVDVFNLKASVKEEHKVILSDGKVLDTENIIIATGSKVRILPIKGIESNLI
                     ITSTEALDLETVPEELVIIGGGVIGCEFAEIFNSRGSKVTIVEMEDRVIPRMDKELSE
                     SLKYSLSKKGINVLTKKKVSEFKEEGNNILVCIEGEEPIKADLCLYAIGREANLSGIE
                     DLDIKIDKGSIVVNSKMETSIPSIYAVGDVTGGVMLAHAAFKMGEVAASNALGVNKEV
                     DLGALPSCVYTIPEVASVGITEEDARKKYNVKVGKFNFAGNGRALASGQEQGYVKVVA
                     DAKYGEILGIHMFGCGVAELINHAASFKALEIPTDEASELIFGHPCTSEALMEALADV
                     NGECLHLPKK"
     gene            31175..34123
                     /locus_tag="OE968_000986"
     CDS             31175..34123
                     /locus_tag="OE968_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HCP7218279.1"
                     /translation="MRQRIKNLIENEDKKNPLTDEAISSRLNIRREDVTFLRNELKIE
                     DSRQRRKVVLIKAIKDILKEEKTINKNDITRRLNSIGFTVSRFTVIQYLKEIQDSGDL
                     KLDKESDDKKEEIINNRENKDIAFDKLIGSSGSLSTIIKLAKAAILYPPHGLHTIIMG
                     PTGVGKSELAECMYKFAVESSRFPKNAPFIVFNAADYSENPQLLLSQLFGHVKGAFTG
                     ADENKEGLVSKADGGILFIDEIHRLPHEGQEILFQLIDKGMVRKLGETRLTHKIDVMI
                     ISATSEPIDSHLLNTFKRRIPVTIEIPELVARPLNERFDIINNFFLIEAQRMGANIHI
                     KSDVLKALMLYDCIGNVGQLRSDIQVACARGLLNQLTNKLKEVNISISDVPGYVKQGL
                     IKIRNCRGKIENYVDGDLIIDSNLQGEIEKKNEDIYTFPDEIYKLTERRHIDLLEQGL
                     DFDVINRIIGGELESCIQKYIKQVKKVSISNNLPDISPIVGKYIVELTYEVIKIASQY
                     LSSLEPNLHLCLAVHLKAAFERLKEGKVISNAHLKEIIGNYPVEYSVAEKVAQYLKER
                     YNINLPKEEIGIIAIYFKMSSRRDMSEQKKIGVLLMAHGRVASSVCEVTNKLLGINHA
                     RYLDMPFEKKPEEMIEEATTIIKDIDEGRGVIILVDMGSLSYFGDIISGKTGINIRTI
                     SRFDTLLSIEVIRRAVLPDLTIDEIVDEVKGIEPQVKEKVSKCNNTKVDFRKPIILTL
                     CITGLGGACKIKKILEENIKSITEKVDIEPIGMIEYPSLDLEIKQISNDKNVIAIVGT
                     IDPQIANIPFFSLVDINDKAKLNQINNLIDTNQIGETNKKYELSDLIHKEDIFVDLQV
                     KSKEEVLKYMSKKLREKGYVTKNFYKKVVERDNLFPTELSDEIAIPHTDGIDVIRPAI
                     SIAILKKPIVWSKSKVKIILLLAVDQKCFNPLSTLLSFIETDEFKKIKNIKDRDFIRE
                     MILDGVNENN"
     gene            34101..34565
                     /locus_tag="OE968_000987"
     CDS             34101..34565
                     /locus_tag="OE968_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HCP7218280.1"
                     /translation="MESMKIISSNLIFKNIEVSNNEDALKFLGQRLFDEQYVKESYIQ
                     AVVAREKKYATGLPTEIYGVAIPHTDIVHVNEPGIAIGILNKPVKFIMMGTDDTEIDV
                     KVVFMLAVKEPQEQLQLLEKLMTIFQDKNILNNIVDLSEESVSDLLNSKLKN"
     gene            34678..34980
                     /locus_tag="OE968_000988"
     CDS             34678..34980
                     /locus_tag="OE968_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCP7218281.1"
                     /translation="MGVTNVAKKILVACGTGVCTSTIAINKLKKALQDIGKLDMVNIT
                     QCKVVEVASKAPDYDLIICTTQVSSSIKTPVINGLPFLTGVGMDKLINDVLEELEL"
     gene            35042..36406
                     /locus_tag="OE968_000989"
     CDS             35042..36406
                     /locus_tag="OE968_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425524.1"
                     /note="with GatAB forms a phosphoenolpyruvate-dependent
                     sugar phosphotransferase transporter for galactitol;
                     subunit IIC forms the translocation channel and contains
                     the substrate binding site; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HCP7218282.1"
                     /translation="MEGLYMEILNFIVGLGAQVMMPIIICIFGLILGTKLGKSLRAGL
                     TVGVGFIGLNTIIALLTDNLGPATQQMVKNLGLSLSIIDVGWPAASAIAFASTVGALI
                     IPIGLVVNIVMLITNTTQTVDVDIWDYWHFAFTGALVAGATQSVMWGVFASVANMVIV
                     LVMADLTAPGIEEYLGMPGISLPHGFTQAFVPIAIVVNKLLDLIPGINKIEINADTLQ
                     KKFGLFGEPLIMGSVIGVIIGIAAKYDIKGILQLGVTMGAVLILIPKMAALLMEGLLP
                     VSEAAQEFIEKRFKNRGKIYIGLDSAVGIGHPVTLSVALVLVPLTILIAAILPGNKVL
                     PFADLAVIPFALVLIVPITKGNVFRTLIIGIIIITSGLLIATNLAPLFTQMALNASFK
                     MPEGATMISSICDGANPLSWVFVKVMNYKVIGGVVFGVIALGMAIYNRNRIINENKKL
                     SIEE"
     gene            36441..36914
                     /locus_tag="OE968_000990"
     CDS             36441..36914
                     /locus_tag="OE968_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218283.1"
                     /translation="MKKYKYDSKRYLLSVTIPGFFMILILIYALFNNYTNFNLNIYSL
                     LIIVCTYGIFNTFISSSNPKKIIIDSKCIHFTSFMTTHKYEIKDIEKIRIREFYNKKI
                     YVKINDGNLFKGRYWIRTNMFNNSIALYSYFIELEECLYPDSLKFRNKKFENKNI"
     gene            37086..37736
                     /locus_tag="OE968_000991"
     CDS             37086..37736
                     /locus_tag="OE968_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HCP7218284.1"
                     /translation="MLLEKLRKEVLQASLDLLNYNLVTLTGGNVSGRDEQTGYIAITP
                     SGMDYRNLTPSDIVIVDVDGNIIDGKWKASVDLSDHLYIYKHREDINSIIHTHSTYSS
                     CFAILNEPIECASTTLANEVGGSVPVAKFSPPTSKKMGKCVIEAIGDKRACLLANHGV
                     IAVGPSVGHALTAAVMLEDSAKVYYLAKSIGTPVLLPDEEIQRARDVFFNVYGQDK"
     gene            37910..38842
                     /locus_tag="OE968_000992"
     CDS             37910..38842
                     /locus_tag="OE968_000992"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HCP7218285.1"
                     /translation="MYYLLNKSTNPYFNLALEEYLFLNDKYNDDIIIIWRNEESIFIG
                     KNQNPYQEVYHDVIEKGEIPILRRISGGGTVYHDLGNINMSFIQKDRQLHEIDFLEHT
                     KFMQKMLSTLGLDVSITERKDLFLNGKKISGSAQSIKRKNSLYHGTLLYDSDLNKLTK
                     YLNSNKATESNATKSVSSKVTNIKFLLEKDINYFLDYCVEYLKSNIKNIKELELDEED
                     IKSVYNIGEDKYKKIEWTYGKTPKFQVVLPFNNESKINIHVNRWKVSKFFISYDDNVI
                     NMDKLLDLNFFKEEIKESILENYPHYIDLINLIF"
     gene            39116..39829
                     /gene="ispD"
                     /locus_tag="OE968_000993"
     CDS             39116..39829
                     /gene="ispD"
                     /locus_tag="OE968_000993"
                     /EC_number="2.7.7.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HCP7218286.1"
                     /translation="MYSVIIVAAGSGRRMNLDINKQFIKLREKEIIAHTIQVFYENIN
                     IDEIVVCIKKEEEDFFKENIINKYNFKNIKIAYGGKERQDSIYNGLKKLDENCDIVLI
                     HDGARPFVDHRIINESIKVAKEKKAVVVGVPVSDTIKIVSDGTVQETPERNLLWAAQT
                     PQTFEYNLIIDAYEQAYKNNYYGTDDSMLVENIGQSVTMVMGSYENIKITSPEDLNIA
                     EQILNMEKRDEVNSRRRII"
     gene            39826..40311
                     /locus_tag="OE968_000994"
     CDS             39826..40311
                     /locus_tag="OE968_000994"
                     /EC_number="4.6.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 2,4-cyclodiphosphate
                     synthase"
                     /protein_id="HCP7218287.1"
                     /translation="MRIGLGYDVHKLTEDRKLIIGGVEIPHDKGLLGHSDADVLIHAI
                     MDSILGALALGDIGKHFPDTDEEYKGADSMKLLEHVYNLITSKGYKIGNIDSTIIAQS
                     PKMAPYIESMRSNISKVLNTDIDNINIKATTEEGLGFTGAKQGIASQSICLLLLTSQN
                     N"
     misc_binding    40406..40614
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            40678..42393
                     /locus_tag="OE968_000995"
     CDS             40678..42393
                     /locus_tag="OE968_000995"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HCP7218288.1"
                     /translation="MKMSKMFMPTLKEIPADAEITSHQLMVRSGMIKKMTSGVYNQLP
                     MGLRVFKKIEQIIREELNKKDCQEILCAALLPSELWKESGRWTAMGEEMFRLKDRTER
                     EYCLGPTHEEAFTDIIRQEITSYKQLPLNLYQIQVKYRDERRPRFGVMRTKTFTMKDA
                     YSFDVDDKGLDKSYQDMFDAYVSIFDRCGLENSPVQADSGAIGGSTSAEFMVKSEVGE
                     DEVVFCSGCDYAANVERAESCNLASQKEEMKELEEVHTPGAATIKELEEFLKTSPDKF
                     AKTLVYEADGKTVVVVVRGDREVNEIKVSNAIGSVIEFALATDDVVRKVTNAEVGFAG
                     PIGINADYVFIDKEIVEQRNIVVGANKTEYHIKNANYGRDFEGIVGDFRNVQEGDKCI
                     VCGKPLEIARGVEVGHIFKLGTKYSESMNANFIDKDGKSKPIVMGCYGIGVERTAAAI
                     IEQHNDEKGIIWPLSVAPYHVVIVPANMKNEEQISIAENIYNDLQAMGVEVLLDDRDE
                     RIGVKFNDSELIGIPMRITVGKNINEGKVEFKLRHKEDKEIIDIEEINEKVKAEFIRN
                     NVRLG"
     gene            42515..43960
                     /locus_tag="OE968_000996"
     CDS             42515..43960
                     /locus_tag="OE968_000996"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HCP7218289.1"
                     /translation="MAKNEKQFVEEITKMEDDFPQWYTDVITKTDLVDYAPVKGFMVV
                     KPYGYALWEKMQEFMDKKFKETGHKNCYFPLLIPESLLNKEAEHVEGFAPEVAWVTHG
                     GNKKLEERLCVRPTSETIICTMYAKWLKSYRELPYLYNQWCSVVRWEKSTRPFLRTSE
                     FLWQEGHTLHETAEEAQEETIQQLEVYKALCEELLAMPVVAGQKSESEKFAGGERTYT
                     IEAMMHDGKALQSGTSHFLGQHFTKAFDITFADREGNLANPYHTSWGASTRLIGGLIM
                     THSDNRGLVLPPRVAPIQVVIVPIAAKKGNVMETVDKIYADLKAKGVAVEVDDRDNYT
                     TGWKFNEWEMKGVPVRVEIGPKDIENNQAMVFRRDTLEKDSMPLEGLADAICDLFDVI
                     HNDMFEKARKHREDNTSIVENMDEFRKALEEKPGFIKTMWCGDAECEAKIKEETGATI
                     RCLPFEQENLGHKCVYCGKEADSMVVMAKAY"
     gene            44400..45881
                     /locus_tag="OE968_000997"
     CDS             44400..45881
                     /locus_tag="OE968_000997"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HCP7218290.1"
                     /translation="MNVRVRFAPSPTGFVHIGSLRTALYNYLFAKKMGGEYILRVEDT
                     DQSRLVEGAIENMLNAMKWAGVNHSEGVILDDSGKVVQKGEYGPYIQSQRLDIYQEYI
                     KQLLDSGKAYYCFCTKERLDEVRDAQRAAGETAKYDGHCKNLSKEEVEANIKAGIPYV
                     IRLRLPENHTIKFTDLVRGDMEFNTNDLDDQVLMKTDGFPTYHFAVVVDDYLMKITHV
                     IRGEEWVSSTPKHVYLYEAFGWEAPVFVHLPNILNKEKKKLSKRQGDVAVEDFKKKGY
                     LPEGLVNYVALVGWSPEDNQELFTMEELEKAFSVERVSKSGGVFDTEKLNWVNQHYIK
                     DGDDAYLTDLAIPFLIEDGFITEEEATNKYDFLKSMISVLKEKLQYVKEVTEHASIFF
                     GDKIEVETEEGREFLRLEHIPTLIDALREKIEKTEVLNAEFVQAMLKEIQKEYKIKGK
                     NLFMGSRIILTGQMHGPDLPKVMEVLGKETCLNRIAYVKNNIL"
     gene            46102..46257
                     /locus_tag="OE968_000998"
     CDS             46102..46257
                     /locus_tag="OE968_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218291.1"
                     /translation="MYSNIDDVKKELKELCLEYVTILEKLKDEKMITEETFEKCSSQK
                     KIFLEEQ"
     gene            46402..47799
                     /locus_tag="OE968_000999"
     CDS             46402..47799
                     /locus_tag="OE968_000999"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HCP7218292.1"
                     /translation="MKVYNTLTRTKEEFVPLEEGKVKMYVCGPTVYNYIHIGNARPFI
                     IFDTLRRYLEYRGYDVTYVQNFTDVDDKIINRSHEEGISPEEVAAKYIKEYFVDCDGL
                     GIKRATVHPQVTDNIQQIIEFIKELEDKGYAYAVNGDVYFDTNKFEGYGKLSGQKQED
                     LEAGARIEVNDQKRHPMDFVLWKAKKEGEPGWDSPWGEGRPGWHIECSVMSKRYLGET
                     IDIHAGGQDLTFPHHENEIAQSEARSGKTFSKYWMHNGYININDEKMSKSKGNFFTVR
                     DISKLYDLEIVRFFMLSAHYRNPVNFSDEMLNQAKAGLERLYNTKEKLEFTLSNLVES
                     PLTEKEVELVKELDDFRQKFIDAMDDDVNTADAVSVIFELAKLINSNVDENSSLEFAK
                     KCLDEFNELTGVLNIVNKKKDTVLDKDIEELIQKRTDAKKNKEFQLADDIRQQLLDMG
                     IVLEDTRQGVKWKRI"
     gene            47784..48197
                     /locus_tag="OE968_001000"
     CDS             47784..48197
                     /locus_tag="OE968_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HCP7218293.1"
                     /translation="MEKDIKMEKTELVTMSPLVLAYLGDTVYETYIREYLIRQNTQRK
                     VNDLHKLAIKYVKAKAQATIIHEIEIELTEEESKIYKRGRNQKSNTSPKNADIIDYKH
                     ATGFEALVGYLYLNNEIERLQYIINKGIKIIERDM"
     gene            48303..49061
                     /locus_tag="OE968_001001"
     CDS             48303..49061
                     /locus_tag="OE968_001001"
                     /EC_number="2.1.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent thymidylate synthase"
                     /protein_id="HCP7218294.1"
                     /translation="MKVKLISHTPEPEKVIAMAAKLCYSPVGTDEIEKDLTDESIEKF
                     LNMLLSIGHGSILEHASFTFSIEGISRACSHQIVRHRIASFSQQSQRYVKLEQFEYII
                     PPEIEKIEKAKELFIDSMKKDQENYDKLVEILFENHYNDLIKNGKNEKTAKRQAEKKA
                     IEDARYVFPNACETKMVFTINARSLFNFFEHRCCERAQWEIRNLAVEMLREVKKVAPI
                     LFKKTGPSCVNGSCPEGTMTCGDIVQVREKFKAL"
     gene            49074..49811
                     /gene="rlmB"
                     /locus_tag="OE968_001002"
     CDS             49074..49811
                     /gene="rlmB"
                     /locus_tag="OE968_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HCP7218295.1"
                     /translation="MASIEGRNPVIEAIKSDREIDKILIANSAKEGSIKKIIGMAKDK
                     NIIIQYVDKHKLDEVSTSHSHQGVIAYASEYKYYELDELIDLAKNKDEDPFFIILDEI
                     TDPHNLGSIIRTADAVGAHGVIIPKRRSVHITPVVAKASAGAVEYMPVCKVTNIVNTI
                     KRLKEEGLWIAAADMDGETFYKQNLTGPLGVVIGSEGFGISRLVKQNCDFIVKMPMIG
                     NVTSLNASVAGGILLYEIFRQRLDKSK"
     gene            49814..50341
                     /locus_tag="OE968_001003"
     CDS             49814..50341
                     /locus_tag="OE968_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HCP7218296.1"
                     /translation="MKKNINHYLIIDGYNIINAWDNLKELAKEDLEDSREKLIDDIIE
                     FSEFMGYKTIIVFDAYNVKNSREKVEKRKHITIVYTREHQTADSYIEKFITSLSKYDD
                     VKVATNDYAEQQMILGKGATRMSARELKLELDRSKNKMKEKNIGLRKKIQRNWLEERL
                     DKETLSKLENIRRKR"
     gene            50406..51053
                     /gene="sigH"
                     /locus_tag="OE968_001004"
     CDS             50406..51053
                     /gene="sigH"
                     /locus_tag="OE968_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigH"
                     /protein_id="HCP7218297.1"
                     /translation="MLVAKEKSYELVDNCQQDEYNIVLRASEGDKIALEYIITKYRNF
                     VKAKAKSYFLIGADKEDIIQEGMIGLYKAVRDFDGSKTNSFKCFAEICITRQIITAIK
                     TATRQKHIPLNSYVSLNKPIYDEESDRTLLDIIATSIVTDPEELIISKEELKNIESKM
                     NELLSDLELEVLELYLNGKSYQFIADKLKRDVKSIDNALQRVKRKLEKHLENRND"
     gene            51127..>51929
                     /locus_tag="OE968_001005"
     CDS             51127..>51929
                     /locus_tag="OE968_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HCP7218298.1"
                     /translation="MAKAKYERTKPHVNIGTIGHVDHGKTTLTAAITKTLYDRYQLGE
                     AVDFANIDKAPEERERGITISTAHVEYETPNRHYAHVDCPGHADYVKNMITGAAQMDG
                     AILVCSATDGPMPQTREHILLSRQVGVPYIVVFLNKCDMVDDEELLELVEMEVRDLLT
                     EYDFPGDDTPIVRGSALMALEDPKSEWGDKIVELFEQIDEYIPAPERDTDKPFLMPVE
                     DVFSITGRGTVATGRVERGVLKVQDEVELVGLTEAPRKVVVTGVEMFRK"
BASE COUNT        21134 a         5581 c         9861 g        15353 t
ORIGIN      
        1 ccccttccag gtcgccaaaa taaaatgctg gtgtggctca acggtagagc agctgacttg
       61 taatcagcag gttgtaggtt cgattcctat caccagctcc atataaaatt aatacggagg
      121 atttcccgag cggccaaagg gggcagactg taaatctgtt gtcatcgact tcggtggttc
      181 gaatccacca tcctccacca aaaaaatgcg cggatgtggc ggaattggca gacgcactag
      241 acttaggatc tagcgccatt ggcgtggggg ttcgactccc ttcatccgca ccatttttat
      301 ttaatttaat aaacgagcgg gaatagttca gtggtagagc gcaaccttgc caaggttgaa
      361 gtcgcgagtt cgaatctcgt ttcccgctcc aaattttatg tttatgttgt aatgtgggtg
      421 catagctcag ctggatagag caacgccctt ctaaggcgtg tgtccggggt tcgaatccct
      481 gtgcgctcac cacatatata ttggggatta gccaagtcgg taaggcacat gactttgact
      541 catgtatgcg taggttcgag tcctgcatcc ccagccaaac agtatggtct attagctcag
      601 tcggtagagc acctgacttt taatcagggt gtcccgcgtt cgagtcgcgg atagatcacc
      661 aatggagagg tgtccgagtg gtttaaggag ctggtcttga aaaccagtga cttcgaaagg
      721 ggccgtgggt tcgaatccca ccctctccgc caaatgccca gatagctcag tcggtagagc
      781 aggggactga aaatccccgt gtcggtggtt cgattccgcc tctgggcacc aaaatgtggc
      841 ggtatagctt agttggctag agcgttcggt tcatacccga aaggtcatag gttcgactcc
      901 tattaccgct actaaaattt aatgtgggcc attagctcag ttggttagag cgcccggctc
      961 ataaccggta ggtctggggt tcgagtccct gatggcccac cacattaaat taacttatgg
     1021 tgggtatagc tcagttggtt agagcgccag attgtggctc tggaggtcgt gagttcgact
     1081 ctcattatcc accccaactt atatggtcta ttagctcagt cggtagagca cctgactttt
     1141 aatcagggtg tcccgcgttc gagtcgcgga tagatcacca aaaaggcggc gacatagcca
     1201 agtggtaagg cagtggactg caactccttg atccccagtt cgaatctggg tgtcgcctcc
     1261 aataaaatgc gctcatagct caactggata gagtgtctga ctacgaatca gaaggttagg
     1321 ggttcgagtc cctttgggcg caccatatga atagcgaggg attatagctc agctgggaga
     1381 gcacctgcct tacaagcagg gggtcacagg ttcgagccct gttaatccca ccagtgcaaa
     1441 cctctagtaa aactactaga ggttttattt ttgattgaaa aagtttttat atttaggagg
     1501 taaaaaattt gtatatagta ataggaaatg aaatagttga tagtgaagaa cttaaaataa
     1561 ttatagataa aaatagtgaa tttaaagttg aaaaagattt aagtaaaagc acaaaaagag
     1621 aagatgtaat agcatatcag ttaagtatag atttaaatta cctagattct cttataaatg
     1681 agcaatgtaa tttagccagt ctatctgatg aagagaaatt tgatgaatat atgactttgt
     1741 ctgatgaact tgcactggat ttagaagagt taatgccaaa atatacaata ataaatgcta
     1801 gagcatataa attagacgag gtagatggaa ttgtaaaaat aatactagct gtagcgtatg
     1861 cagatttagg gcacttaaaa ctttctgatg tagtaaagag gctatctaga caagtagatt
     1921 aggatatgaa tatgaactat attaaaaaaa tgtataaaat cttacgtaaa gatgaaaata
     1981 attatgtaaa catagaaaaa aacagtataa aatcaagtca attgtagaaa ttttcacata
     2041 aattcatctg aaattctgta aaaaatgcct taattttaat gaggtaaatc gagtttacac
     2101 agtctaaaaa ttacttatat ttataaattt atcttattaa ttaaggaact ttcttaaaca
     2161 tcttcaaaaa taaagtattt tagtctataa tctttaatat tacacaaaca ataaaggaga
     2221 agaatagagt atgcttaaaa agtttaataa aatactagtg gctaatagag gcgaaatagc
     2281 tataagaata tttagagcct gttcagaatt ggggataaaa agtgttggta tatacagtaa
     2341 ggaagataag tatggattgt ttagaacaaa agcggatgaa tcatatttga taggagaagg
     2401 taaagggcca atagatgcat atttagatat ggatggaata atagacctag caaagagaaa
     2461 aaaagttgat gctatacatc caggatatgg ttttctagcg gagaatgcag aatttgctcg
     2521 taaatgtgaa gagaatggaa ttacttttat aggaccatca tctaaggtaa tgaatatgat
     2581 gggggataag attaactcta aaaaaatcgc aaaagaagtt aatgttcaaa ctataccagg
     2641 agtagaaaaa gcaataagaa gtactgaaga agcaaaggaa gttgcaaaca aaataggata
     2701 tcctgttatg ataaaagcat ctaatggcgg tggcggtaga ggtatgagaa ttgtacatcg
     2761 cgaagaagac ttagagcttg aatatgaaac tgcttgtagt gaatcaagaa aagcttttgg
     2821 agaagatatt atatttatag aaaaatatat agctgatcca aaacatatag aagttcaaat
     2881 attaggtgat aattatggaa atatagttca cttatatgaa agagattgtt cagttcaaag
     2941 aagacatcaa aaaataatag aatatgcacc agctttttcg ttagatgata aagtaagaaa
     3001 agagatatgt gaagatgcag ttaagttatc aaaacatgtg ggttattcta atgcgggaac
     3061 attagaattt ttagtagatg caaatggtgg gcattatttt atagagatga acacaagagt
     3121 acaggttgaa catactgtaa cagagatggt tacaggaata gatatagttc aaagtcaaat
     3181 actaatagcc caaggttaca gcttagatag tgaagaaatt aatataaaat cacaagatga
     3241 tgtggaaata agaggttact ctatccaatg tagaataact acagaagacc ctaagaataa
     3301 attcatgcct gatacaggta aaattcaagt ttatagaact ggttcaggat ttggtataag
     3361 actagatgga ggaaatggat ttacaggggc aaacataagt cctcattatg atagtttatt
     3421 ggttaagaca atatcttggg atagaacatt ccaaggagca ataaataaaa ctataagatc
     3481 tataaaagaa cttagagtta gaggtgttaa aactaatgta ggattcctag ttaatgtttt
     3541 aaataatcct atattctcaa atggtaaatg tagtactaag tttatagatg aaaatccaga
     3601 tttatttgaa ataacagaaa gtaaagacag aggaacaaaa ttacttcaat ttataggaga
     3661 tgtaattgta aatgataatg cttgtaaaga aaaaccatta tttgatgcat tacatgaccc
     3721 aagaatggat aaggatggtt caaaatcaga aggaagtaaa atacttttcg ataagttagg
     3781 taaatctgca tatatagaaa agataaaaaa tgataagaaa ttactattaa cagatacaac
     3841 aatgagagat gcacatcaat cattattagc aacaagaata agaacatatg acttattaaa
     3901 agctgctaag ccaacagaaa aatatcaaaa ggatttattc tcacttgaaa tgtggggagg
     3961 agctacttat gatgttgcat atagattttt aaaagaatct ccttggcgta gattacaaaa
     4021 gctaagagaa gaaataccaa gcataatgtt ccaaatgttg cttagagcat caaatggagt
     4081 tggatataaa aactatccag ataatgtaat agaagaattt acaaaagaat ctgctagaca
     4141 aggtatagat gtatttagaa tatttgattc attaaactgg gttgaaaata tgaaaccatc
     4201 tattaataca gctttagaaa ctggaaaaat tgttgaagca actatgtgtt atacaggtga
     4261 tatactagat aagactaaaa ctaaatacaa tctagaatat tatattaaaa tggcacaaga
     4321 attagaaagc ttgggagcag atataatagc aataaaagat atgtcaggtc ttcttaaacc
     4381 atattcagct tacacactag ttaaagagtt aaagaaaaat gtaaaagcac caatacattt
     4441 acacactcat gatacaagtg gaaatggtgt agcaacttgt ttaatggcgt cagaagctgg
     4501 agtagacata attgatgctg cattagaatc tatggcagga cttacaagtc agccatcact
     4561 taatgctata gtagaggcac ttaagaatac agagagagat acaggaatag atttatttgg
     4621 atatgatgag ttaggaaaat attataagga tttaagaaaa gtttataata aatttgaaag
     4681 tgatttaact aattcttgtg cagaaatata taattttgaa ataccaggag gccaatatac
     4741 aaacttaaaa cctcaagctg atagtttagg attagttaat agatttgatg aagttaaaga
     4801 aaaatataaa gaagctaatg aagttgtagg agatataata aaagtaactc catcttcaaa
     4861 agttgtagga gacttagcta tctttatgac taaaaataaa ttagataaag ataatataat
     4921 agaagaaggt aaaaatttat cattcccaga ttctgttgtg gattactgta aaggtatgat
     4981 tggtcaacca gaaggtggaa taccaaaaga tttacaagag gtagttctaa aaggtgaaga
     5041 agctataaca gtaagaccag gttcattatt accagcagaa gattttgatg aaatagctaa
     5101 atatctaaat gaaaagtatg atataaatgc taatataaga aatgttataa gttatgcttt
     5161 atatccaaaa gtatatgaag attatatcaa acatctacaa cattataatg atatatctaa
     5221 acttgaaagt gatgtattct tctatggatt aaataaaaat gaagaatgtg aagtagaaat
     5281 agaagaaggt aaggtattaa caataagatt agttgaaatt ggtgaagtta aggaaaatgg
     5341 atttagaact ataggatttg agttaaatgg aatggttaga gaagtagaaa taaaagataa
     5401 gaatttctct ggaaaaatta ataatgttga aaaagctgat atgaatgacc ctcttcaaat
     5461 tggagcaagc ataccaggaa aagttataaa aataatggtt aaagaagaag atgaagtaaa
     5521 agcaaatcaa ccattaatcg ttatagaggc tatgaagatg gaaactataa tagttgctaa
     5581 gactgatgga gtaattaagt caatcaaagt aaaagaagat gatatggttg aagataaaca
     5641 attattaatg ataatgaagt aatttaatta aaataaatta aaaagcactc tgaaatgttt
     5701 aataaaaaat gttttagagt gtttttattt attttaatta aatatttgtt aaaaaaaaga
     5761 ggacaattac ctccagatgt agaaataaag ctagtaagga aaatgttatc taaaaattct
     5821 aaatatagta aatattttcc ataatatttc ttaggaaata acagcaaaga taaaatacat
     5881 aaatttaaaa ggtgggtgct tatatgaagg tttatgatag taaaatgttg agaaatgtag
     5941 cggtattagg acatagcgga tgtggaaaaa caaatctaat cgaaactata gcttacacag
     6001 caaacactaa taagatacct aaattaacag acaaggtaaa tatgacttat agcatgggat
     6061 taatacctat agagtataat gattataagt ttaacttatt ggatacccca ggatattttg
     6121 actttagcgg agacgttgtg tcatctctta gagcaagtga tgcagcaata atagtaatag
     6181 atgcaacagc gcctattcaa gttggtacag agaaatcatt agaactaact gagagtattc
     6241 ctaagataat gtttataaat aaaatagata atgaaaaggc aagatacaaa gatgcaatag
     6301 caatgttaag agaaaaatac aataataaga tagttcctat gataagtcct atatacaaag
     6361 ataaaaactt tgtaaagtta cataatgttt ttgaaaacat agatgattta gaaggtgaat
     6421 ttaaggaaca agctatgagt gttaaagaag cattaatgga acttatagca gaaactgatg
     6481 accaaatatt agataaatat tttaatggag aagaactaac tacagaagag atacaaaaag
     6541 gtattattat aggtatacaa agaggtgata ttatacctgt aatatgtggt tcaactataa
     6601 ataatatagg cacaaaggaa atattagata caatatcaag ttatttagaa cctatcttta
     6661 cagaggaaag caaaccattt aggggattag tatttaaaac tatggttgac ccatttgttg
     6721 gaaagatgtc atatataaaa attactgagg gtgtactttc taaggataaa gatgttttta
     6781 atataaataa aaatgtaaaa gaaaaaatag ctaatatata tacattgaga aatagtgaat
     6841 tagtagaaat agaaaaagct aaagctggtg atatagtagt tataactaaa gttaattctc
     6901 taaaaacagg agacactata tctgcagata aagatgcaga agctttagaa aagatagatt
     6961 ttcctaaacc acaaatatat tatgcagtaa ctcctaagaa taaaggtgat gaagaaaaag
     7021 tagcatctgt attaaataaa ctagtagaag aggaccctac attacattgg tatagaaata
     7081 cagagacaaa acaagcactt ttaggaggtc aaggagaact tcatataaaa acaattaaaa
     7141 ataaaatgaa agataagttt ggtgttgatg ttgaattgaa tgaccttaaa gttccttata
     7201 gagaaactat aaaaggaaca gctgatgtac aaggaaaaca taaaaagcaa tcaggtggtc
     7261 atggtcaata tggagacgta aaaataagat ttgaaagatg tgaatctgat tttgaattta
     7321 cagaagaaat atttggtggt tctgtaccaa aacaatatat accagcagtt gaaaaaggtt
     7381 taaaagactc tatgcaaaaa ggtatattag caggatatcc tgttacaaac ataaaagcta
     7441 cgctttatga tggttcatac catgatgtag actcttctga aatggccttt aagatggcag
     7501 caagtgcagc ctttaaaaaa ggtatggaag aagcacaccc aatactacta gaacctataa
     7561 tgaaacttaa gataactgtt ccagaagaat atatgggaga tgtcatgggt gatataaata
     7621 agagaagagg aaaaatattt ggaatggaac cagatgacaa agggaaacaa ataatatttg
     7681 cagaagctcc acaagcagag acatttaaat atgcaataga tttaagagca atgacacaag
     7741 gtagaggata ctttgaaatg gaattagaga gatatggaga ggttccatca cagtttgcag
     7801 aaaaaataat tgggttagct actgcaaagt aatgaacaaa ataaatagaa aaataattaa
     7861 tatatattat taaaaatatt tttagggttt taactaggta taggtttatg ttaggtaaac
     7921 ttatacctag tttttataca tttttgatga ataaaaaaat atataatact ttcttaaata
     7981 ttttaataaa aagaaagtat ttttttatta ttatttttac aaatgtttag taataaagat
     8041 gagaaggtat atttaaaata taaagtattt aaagttctga aatctaatca tgaagcaaaa
     8101 aattagcatt tggttatcaa taaatataat aaataaaaac tcataattaa tgaaagaata
     8161 aattcatgtc taaatttcta taaaaaattt aaatttatac aatttagggc tttaaaaatt
     8221 taaataatag gtgtaaaata atagtcaaag aaagtcaaaa ataaaaaggt gtgtggtgat
     8281 attaatggca actatgacag atataattga aaaatttatt aaagatttga tggaagaaga
     8341 taatagcata caaattcaaa gaaatgaact agcaaacttg tttagttgtg caccatcaca
     8401 aataaattat gtcttaacaa caagatttac aatagataga ggatattaca ttgaaagtaa
     8461 aaaaggtggc ggaggatatg ttcaaataga aaaaatacga aaaagtaaag atgggcatat
     8521 tagagaacta ctaaatgaaa aaataggaag tcagatatcc tataaaaaag caaaagaatt
     8581 attagaaggt ttaaaagagt cggatttgat taacgaaaga gaattaaaat taatattata
     8641 tgcaatagat gataaatcat tgtgtatgcc aatatatgaa ttaaaagaga aggtaaggtc
     8701 taatatttta aagaatataa taataggatt atttagtata gaggagtgat aatttatgct
     8761 atgtcaaaaa tgcaataaga ataaagcatc tgtatattat aataagatag tcaatggaga
     8821 aaaaacagag atgtatttat gtagtgagtg tgcaaaagag aatacagaaa tgaattttaa
     8881 cttagatatg cctttttcaa tgatggatat attttctaat ttaggttttc aacctaaaaa
     8941 agaacttgag gaaaagctag tttgtcctaa atgcaataca acatatagtg agtttaagaa
     9001 taatgggaga tttggatgta gtgaatgtta taatgcattt agtagtcaag taaatccaat
     9061 gcttcaaaat atacatgggc atatagaaca tacaggaaaa gcacctaaaa aatcttttta
     9121 taagataagt gtagaaaatg agattaaaga actaaaagaa gatttagata gagctataaa
     9181 aaatgaagag tatgaattag cagctcaatt tagagataaa attaaatatt taaaaggttc
     9241 tattgactaa gattggagtg atattatgaa agagaacata gtcatgaaat caagagttag
     9301 gctagctaga aatttaaata actatccatt tccaaataaa ttagataaag aatgtgccat
     9361 ggaaataata gaaaaagtaa aaaatgcgtt tattaattct aacttagaac aaaaagaaga
     9421 atttgatttc tataaaattg aagatttaga ccaatctaaa aaaatgctta tggttgaaga
     9481 acatataata agcccagatt tagcagaaaa tgataaaagt gcagttatag taaaaaaaga
     9541 taaaactata agtataatga taaatgaaga agaccatata aggatacaaa ctatatgtga
     9601 tgatttaaac ttagaatatg catatagtgt agcaaatgaa atagatgatt tgttagaatc
     9661 aagtttagaa tatgccttta acacaaagct aggttatcta acatcttgtc caactaatac
     9721 aggaacagga atgagagctt ctgtaatgat gcatttacca gcattaagtc aactaggcta
     9781 tatggatgaa ctttataaaa tttcatcaca aataggtata gcaattagag ggatatatgg
     9841 agaacgaaca gaagcattgg gaaatatata tcaaatatct aatcaactta cacttggaag
     9901 aacagagtct aatattatag aaaatgtaag tggacttaca aaagatgcaa tttcaaaaga
     9961 aataaaagct agagaaatat tgcaaaaaaa attaggtata aaactagaag ataaaatatt
    10021 tagatcgata gggacacttg aaaattcaag agtaatgagt agcgcagagg caatgagcca
    10081 tctatcaaat ataaaaatgg gaatagaaat gaactatata gataaactag atttaagggc
    10141 tatagaacaa cttatgatag gtatacaacc agcgcatcag tcaataatgt ataagagtga
    10201 tgatgttgag aatagagata taaatagagc aacatatatt agagaaactt tggaaaaatt
    10261 aagaggaggg atgaattgtg aacttcaata gatttacaca aagagctaaa aaggcaattg
    10321 atttagcgtt tgaatctgct aaaagtctag gacacaatat tgtcggaagt gaacatatac
    10381 ttttaggtct tttaagagaa gaagaaggta tagctgctaa agttctaagt aaagttggat
    10441 ttacagaagc ttatttagaa ggcaaaatag ttgatatgga aggtaaggga gaagaaatct
    10501 cagaagatat agtattaagt ccaagaagta aacaaatact tgaattatca ggaatgtttg
    10561 caaataaatt aaaaacaaat tatattggga ctgagcatat attattagca attattcaag
    10621 aaggtgaagg aatagctaat aagattttaa attatgctgg agtaaatgat aggactttag
    10681 cccaattaac aattgatatg atgggtatta gtgataaaaa tcaatacaaa gcagaaaata
    10741 gttacacggg caaccagaat caagcagaat ctaaagtact tgataagtat ggaagaaatc
    10801 ttacactata tgcaaaacag aataaaatag accctgtaat aggtagagaa aaagaaatac
    10861 aaagagtaat acaaatatta agtagaagaa ctaaaaacaa tccagtgttg ataggagacc
    10921 caggtgtagg gaaaacagcc atagctgaag gtctggctac aaatatagcc ttaggaaatg
    10981 ttccagaaac actaaaaaac aaaactttat actctttaga gatgggttca ttattggctg
    11041 gggctaagta tagaggagaa tttgaagaaa gaattaaaga agttgtagat gaagttgtta
    11101 aaaatggaaa cataatctta tttatagatg agatgcacac aataataggg gctgggtcta
    11161 ctggagaagg ctctatagat gcttcaaata tattaaagcc agccttagca agaggagaaa
    11221 tacaagttat aggtgcaact acaattgatg aatatagaaa gcatgttgaa aaagattctg
    11281 ctctagaaag aagattccaa ccagttatgg tagatgaacc aactaaagag gactcaataa
    11341 aaatattaga aggattaaga gataaatatg aagctcatca taaagttaaa ataactgatg
    11401 atgctataaa ggcagctgta gaattatcaa ctagatatat atcagacaga tatctgccag
    11461 ataaagctat agacttgatt gatgaagctg catcaaaagt aagattaaaa gaaaatacac
    11521 ctccttcaga aataaaaaaa ttagaactag aaatagaaaa tatagataaa gaaaaagaag
    11581 aagcagtaag atgtcaagac tttgagaaag cagccaaaat aagagatgaa caaggtctac
    11641 ttaaaaaaca attagaagat gttagagaaa gatggaacaa gtcatctaaa cattcagatt
    11701 tagttgatgg agaagttatt gctgaagtag tgggcttatg gacaggaata ccagttaata
    11761 aaattcttga agaagaggct gatagacttt tgagacttga ggaaatactg cacaatagag
    11821 ttataggtca agaacaagca gtaaaatcta tttcaaaggc aatcagaagg tcaagagcag
    11881 gtcttaaaga ccctaataga ccaattggtt catttttatt tttaggtcca acaggagtag
    11941 gtaaaacaga attatctaag gcattagcag aagtgcaatt tggagatgaa aatcaaataa
    12001 ttagaataga tatgtctgaa tatatggaaa aacatgctgt gtcaagaatg ataggttcac
    12061 ctccaggtta tgtaggtcat gatgaaggtg gtcaattaac tgaaaaagta agaagaaatc
    12121 catattcagt tatattattt gatgagatag aaaaagctca tccagatgta tttaatattc
    12181 tgttacaaat tctagatgat ggtagactaa ctgattcaaa aggaagaact gtagatttta
    12241 agaatactat tgtaataatg acatcaaatg ttggagcatc tacaattggt agacaaaaaa
    12301 ctttaggatt tagtatagct aaaggagacg aagaagaaaa atctcaatat gaaaaaatga
    12361 aagaaaatat aatgggtgaa ttaaaacaaa gattcagacc agagttttta aacagaatag
    12421 atgatataat tgttttccac tcactaaatg aaaatcatat atcaaaaata gtacttttaa
    12481 tggcagcgaa actacaagag agattaaaag aaatggatat aaaattagaa atgagtgatg
    12541 aggctgttaa attaatttct aaatctggat ttgacttaga atatggagca agacctctta
    12601 aaagagcttt acaaaaagag ttggaagatg agctatctga agcaatctta aaaggtaatg
    12661 tgaaaaaggg aagtaatgta gtagcaaaag tcaaagatga aaaaatagtt tttgaaacta
    12721 aataatttaa tagagttgca ttttaaaata ttgcaaatat aagttttata atctaaacaa
    12781 aattttaagg gcaatgaatc tataataatt cattgtcctt aattatttta tttaatcttt
    12841 acatattgtc tttcagatat gctaaaatta tagtatagaa taaaaaatta aggatgataa
    12901 aagtatggca aaaataaaaa caaaatatgt atgtcaatct tgcggatatg aaacagctaa
    12961 atggcttggt aaatgtccag aatgtacaaa atggaataca tttgtagaag aaatagacca
    13021 aaaaagcacc aaaaaagagg tctttataat agataaatct tcatctaaac cagtcagtat
    13081 aaactcaata gaaagtaaag aagaagagcg gtttacaaca gatataaatg agttagatag
    13141 agtgcttgga ggaggtatag ttaaaggctc tttagtgctt gttggtggtg accctggtat
    13201 aggtaaatca acacttttaa tccaagtatc tagtaatgtt gccaatttag gaaaaactgt
    13261 tttatatata actggagaag aatcagaatc tcaaataaaa atgagagcta aaagattagg
    13321 tattaactca gaaaatttat atatatttgc tgaaaataat ttaagtataa ttgaatctta
    13381 tttagaaagt gtaaatccag aattaataat tctagactca attcaaactg tcttcagtcc
    13441 agaaatatcc tcggcaccag gaactgtcag ccaaattaaa gaaggtactt caaaattcat
    13501 gaaaatttct aaaaaaatgg gaatttcaac gttcatagtt gggcatgtta caaaagaagg
    13561 ttcactagca ggaccaaaat tattagagca tatggttgat actgttctat attttgaagg
    13621 agaaagatat aatacttata gattagtaag agctgttaaa aatcgatttg gttcaactaa
    13681 tgaacttgga gtatttgaaa tgagggattt aggattagta gaacttgata atccatctaa
    13741 aattttaatc tctgaaaaac caaaagatgt agcaggttca gtaataatat ctactgtaga
    13801 aggtacgaga ccaatgttac ttgaattgca agcattagtt tctcctacaa gttttggtat
    13861 accaaaaaga acatctacag gagtcgatta caatagagta ggtatgttat tagcagtatt
    13921 agaaaaacgt gttggtttgc aaatacaaaa tcaagatgtc tatataaaca tagttggagg
    13981 aataaagata aatgaaccct caattgattt agggatagcc atttctgtag catctagttt
    14041 tagaaatata ccgatagatg aagatatagc tgttacagga gaagtgggac ttacaggaga
    14101 agttagagca gtaagcttta tagaaaagag aatagctgag tgtaaaaaac ttggatttaa
    14161 aaagatagta gttcctagaa gtaattatga tgttgtaaaa gagaccaaag gcatagaaat
    14221 atggccagta gataacttaa gacaagctat aaatatagta cttgggagga atcaataaat
    14281 atggagaatt ttctagataa taaaaatatg ctatatgcat taaaaatgat atctcctgga
    14341 actccactta gattaggtct aaacaatgta ctaagagcta agactggtgg attaattgta
    14401 attgcaacaa acgaagatgt aatgaaaata gtagatggag gatttgctat aaatgcagaa
    14461 tattcaccat catatctata tgaattagct aaaatggatg gagctatagt tttaagtggt
    14521 gatgtaaaga aaatattatt tgctaatgca caacttatac ctgactattt tatagaaaca
    14581 tcagagacag gaacaagaca tagaacagca gaaagagtag caaaacaaac tggtgctata
    14641 gtcataggaa tttcacaaag aagaaatgtt ataacagttt atagaggaaa tgagaagtat
    14701 gtagtcgaag atatatctaa gatatttact aaggcaaatc aggctataca aactctggaa
    14761 aaatataaga cagtattgga ccaagctgta acaaatttaa atgccttaga gtttaatgat
    14821 ttggtaacta tttatgatgt tgcattagtc atgcaaaaga tggaaatggt aatgagagtt
    14881 acaagtataa ttgaaaaata tgtgatagaa ttgggtgatg aaggaacttt agtaagtatg
    14941 caattagaag aattaatggg tacaaccaga atagaccaga aattaatatt caaagattat
    15001 aataaagaaa acacagaaat aaaagaactt atgaaaaagg tcaaaaattt aaattcagaa
    15061 gaactaatag aattggtcaa tatggcaaaa ctattagggt atagtggttt ttcagaaagt
    15121 atggatatgc ctataaaaac aagaggttat aggattctta gcaaaataca tagactacca
    15181 acagcaataa tagaaaactt agtaaattat tttgaaaact ttcaacaaat tttagatgca
    15241 tctattgaag aattagatga ggttgaagga ataggtgaaa taagagcaac atatataaaa
    15301 aatggactca taaaaatgaa acaattagtc ttattagata gacacatatg atgaatttta
    15361 aatgaatttt actacttttt tcttgaatat aatatacact ttggtctata atagataagt
    15421 ataactaggg ggtgaagcat tgataaggaa agtaacaaga atattgttta ttttacttgg
    15481 atttacaata ggtataacaa cctatttaac attaatgaaa gattttgaaa tattaacatt
    15541 tggaaaagaa acatatggtt atatcgcagc tgtagtagca ggtataataa tagccatttt
    15601 aggatatctt atagaaccat gggttgtaaa taaagtaaaa gaaattgcta aaatagtgga
    15661 taaagaattg tcaaaatatc ctcagactga tatattgtta gggtctatgg gtcttatagt
    15721 aggatttgtt attgcgtatt tattaagtgg attagtaaat agaataccaa tagtaggtgg
    15781 aatactatcc ttactattat atttattcct aggatatctt ggaatgaaag ttgcgcttaa
    15841 aagtaaaaat gatttattta atattggaaa actaggaaga ttagcaaatc ctattaagga
    15901 taaagataag gataaagaaa ataaaaaaga agtaaaagcc attcctccaa aagtattaga
    15961 tacaagtgta ataattgatg gaagaatagc tgatatttgt aagactgggt ttatagaagg
    16021 aaaacttatt attcctgctt ttgttttgga ggaactaaga catattgcag attcttcaga
    16081 tgatttaaaa agagtaagag gtagaagagg tctggatata ttaaatataa ttcagaaaga
    16141 attaaatata gaagttgaaa taagtgagag agactttgat gatatagcag aagttgatag
    16201 taaattatta aagcttgctc aggttttaaa tggaaaagtt gttacaaatg attataactt
    16261 aaataaagtt gctcaattcc aaggtgttga agtattaaat ataaatgagt tagctaatgc
    16321 tataaaacca gttgctatac caggtgaaga tatggttgtt caagtggtta aagaaggaaa
    16381 agaggctcaa caaggtgttg catatctaga tgatggaact atgatagttg ttgatggagg
    16441 aagaaaatat atgaatgaga ctataaaagt actcgttact tctgttcttc aaactcctgc
    16501 aggtagaatg atatttgcaa aacctaaaaa ttaatatgtt caaagaaacc tataatttgg
    16561 gctgtttatt ttaaatagat ggtccaaatt tatttattta taacgataat gtttaatgta
    16621 ttcttaaaga tggggattta aatcagaaag cagggagaat ttatgagaaa aaagattata
    16681 tctttcttag caacatttat cataatatta acatcagcaa gtcagtatag ttttgcagat
    16741 gatatatcaa cacgtggaaa agtaatattt atagatatga atagaactag tatgagtaat
    16801 atgttaagaa taaaatcatt aagagaagaa ctagacaata gagggtatat tggcttgatg
    16861 aatataagag gcgataaagg aagtgatgat agaaggtcat atgctagtat gggtgctggt
    16921 ggtagagcta atgtggctaa tgaagaagat attaattttg aaagctcgag taaggataga
    16981 aatatagttt ttgaatcagc tacaggaaaa agtgcaaaag gtataaataa tttaactata
    17041 aataagtcta taaatgaaaa tttaaacttt ggagagtatg gttctgtatt agggtcatta
    17101 ggacaaagtt tatctgataa tggattaaaa gcatctgtat tgggtaattc agatataatt
    17161 gaaaatggtc aacttataaa aaatagaaac ttatgtctaa ctgcaatgga tgaatatgga
    17221 agaataccta atggaaatgt agatactata aataaaaaag acttatctat gccttatgga
    17281 atatcaactg attatgataa attgattgta gagactaaag aaacttacaa aaataatgat
    17341 gtgatttttg tggagcttgg agacacatat agattagatt tatataaacc aaatttaaat
    17401 gaaaaaacat atgagagtat gaaagataac atagaaaaaa atatagatat atatttaaaa
    17461 aatatatttt ctatggttga agaaaatgac actatctaca tagcaagtgc atttccaagt
    17521 gatttagatt ataaaaataa aagaagactt tctccaataa taaaattaaa tggagaaggg
    17581 aaaggtatat tatcatcttc aactactaga agagaaggta ttgtaacaaa tttagatgtt
    17641 ggggttgaaa tattagacaa ctttaatata aaaaatcaaa atatggttgg aagaaaatat
    17701 gaacttatta acagagatga taataaagaa tttttgatgg atgaatatca aaagatagta
    17761 tctatttcaa gcataaggtc tacaatactg aatggttttg taagtatagt tttcttgtca
    17821 tggatagttg ctatgattgc aattttattt agaaagcata tatcaaaaaa ttataaagaa
    17881 acaacatttt ttatattaaa ggaactttta aaaataggaa tagtaatgcc actgtcattt
    17941 atgataacac caataatgaa tttcaaaaca ccattagcaa tatctttagg aataattata
    18001 ataacactta ctatatatct tataagtaaa gttttaataa agaacgattt aaaaaacatg
    18061 ctgtttttta ctggattaac catagtaatt atggttattg atgctgggtt tggctcatat
    18121 ttaatgaaaa gcaatgttat gagttatgat tgtataattg gagctagata ttatggagta
    18181 ggaaatgagt atcaaggtgt ggcaatcggt agtgcaatat ttacatttgc aattttactt
    18241 acatataaaa atataccaaa gtggtatata atagtttttt ctttggttat cttaattaca
    18301 agtgcatctc caattatggg agcaaatgtt ggaagtgcta tttctgaatg tgttgcattt
    18361 ttactattta tactattgat atataatgta aagatagatt tcaaaaaaat cgtattatta
    18421 ggtatagcag tagtatttgt attaggagtt tttgtagcaa tagatatgat tttgggaagt
    18481 aattcacatt taggtatgtt tgtaaaagaa atttacttta atggaccagg agaaataata
    18541 caaacattta gtagaaagat agagatgaat ttaaagctag ctcaaaccag tgcatgggta
    18601 aatatactgt taactggaat aggtgtaatt ttagttctta tgattaatca gattagatac
    18661 tttaagcaac tgatggatga gtatccaatt gtatttaaag gatttatagc atcaatagca
    18721 ggatgtttag taactctttt agtgaatgac tctgggattg tgtcatcagc tacagccttt
    18781 atttatgtaa ttgtacctat gataacatta agtataaatc ttacagcatt aaaagaataa
    18841 gtactgtatg aataatatgt aaatattaat acattaattt aacttcttta tttacaaaat
    18901 aaagaagaaa gtttataaaa aataaattat aataaaaaag agtttatctc aaaattgatt
    18961 attctaatca aattttaaga taaacttttt ttattataaa gataaataac atataacctc
    19021 atattttagg tagatttttt tcttatatgt ttaggagtgc atttaaattt ttccttaaaa
    19081 attctgtaaa ataattttgt attagtaaat ccatgagctt ctaatatact gcataaggta
    19141 tcatttgtgt taattaaatc tttataaata tgagaaatac gcacatcatt taaatactct
    19201 aagtaagttt gtcccatata ctgtttaaat tttctacaaa aatattctgg ttgtaagtgt
    19261 gctaccttag cgattttgtt aatagaaata ggcattttgt aattaatctt tgtatattct
    19321 aaaactggtt caaattttga caaatcaagt actgtttttt tcatattttt attacctaca
    19381 gatattttaa agtttgtata taattcaaat aaaagttcaa ataataagct tgtaaagagc
    19441 agattagctg caggaggaga actaagttta atttctctca tgttttctaa tataagttta
    19501 actttacttg aatttttttt atagttattg tcattggcat taaccttaaa gtcaaaatag
    19561 caatttttaa aatcagggat atatttgttt agaaaagaca atggtacttg caataatata
    19621 gaggtatttt gataaataca tctagttgag tgaataattc cagaattaat gaacatacac
    19681 tcattagctt ttaaattata agtgtaaccc tccatgttaa tttgtaaatc accagaagtt
    19741 atataaatta tttctaatga gttatgccaa tgatttgcta cataactacc actatcatca
    19801 aatagtttga aattaacatc taaattatca ataggttcaa ttatttcatg tgaaaaatta
    19861 tttctgttca taataatatc ctccttataa ttttaaatta taaatagtaa atttataatg
    19921 ttcaatatta aaaagataat atagactaat aaattagata ataaacatac ttaagaaaac
    19981 ggataaaatc aaatataata actgtatatt aaaataactt aaaaaaatta ttttattata
    20041 agtgcaaaat atacctattt aaataagata agaggggagg attttatgtg tatataaaag
    20101 gtgtaaattt aggaggttgg ttagttttag aaaaatggat gacctcaagt ttatttgaag
    20161 gcacagaagc tgaagatgaa tactatttac caagacagct ttcaagagag gcatatgaat
    20221 ctagaattaa gactcatcgt agtgaataca tcacagagag agattttgca acgattaaat
    20281 ctatgggatt taattcagtt cgtataccag taccatactt tatttttgga gattgtgaac
    20341 cattcatagg atgtgttaaa gaacttgata aagcatttgc ttgggcagat aagtatgggc
    20401 ttagtatatt gatagactta catacagttc caggaagcca aaatggattt gataatggag
    20461 gaatatcagg tatatgtagc tggtcacaaa atccagaata tgtagcgttt acattaaatg
    20521 tattagaaag acttgcaaaa cgttatggga tgaggcatga attgtatgga atccaaattt
    20581 taaatgagcc tataacagaa agaatgtgga acataatgaa tgttccaaat cggtttaagg
    20641 ctgtagataa ggagatggca agggggagta aacctaattc attagagttt ttacgtgatt
    20701 tttatataaa agcatatagg gtaatgcgtc cttatatgag agaggaaaac gttatagtgt
    20761 ttcatgatgc atttgaatta aaagcatgga aagactttat gagagaggaa gaatttaaaa
    20821 atgttgttct agatacacac caatatttga tgttagctga agcagatgga tgtgaacaaa
    20881 gtattgatag ctatctcaaa tatattagag aaaattatgc taaagatatt ttacaaatgc
    20941 aaaaatattt tcctgttata tgtggggagt ggagcttatt taattcatat gtttgtggta
    21001 tagatacaaa tggaggtcaa tcacctctaa atgggattga atcaaatata gataaattat
    21061 caaaagacga taaaagagaa ttatatagga agatagcaaa agcacagctt gatgcatgga
    21121 gaaatggaag tggtcactac tattggaatt ataagttatt actagataca gttaatgaag
    21181 aaggttggat aggatgggat agttgggacc taggcaaatg tgtagctcaa gaatggtatc
    21241 ctatagaata ttaaactaaa attggaggaa aagatatgat taaaaaccct atacttccag
    21301 gttttaatcc agatccttgt atttgtagaa agggagatga ttattatctt gtagtttcat
    21361 cttttgaatg gtttccaggt atacctgttt atcactctaa agacttaaaa aattgggagt
    21421 tatatactca tattttgaca gatgaaacaa aaatagattt gaagaagctt ccttcatcta
    21481 aaggaatttg ggcaccctgt ttgacttatt gtgaagaaga agatttattt tacatagttt
    21541 atggaattat gaactctatg aatgcaagat attttgatgt tgataattat ttaattacat
    21601 caaaagatat aaagggagag tggagtgaac cagtatatct acactcatca ggttttgatg
    21661 cgtctatttt tcatgatgat gatggtaaaa agtggattgc atcattagac tgggagacta
    21721 gagaaggata tgaaaaacct ggtgttatat gtttagtgga atactgtaca aaaaagaaag
    21781 aaatagtagg atatccaaag agaatatggt cagggggaac tgatagaggt tgtattgaag
    21841 caccacatat aacaaagcgt ggagattact attatataat gtgtgcagaa ggtggaactg
    21901 gatatggtca tagtgtaact atgggaaggg ctaaaaatat atggggacct tatgaaaaag
    21961 attcaatgaa tccaattgta acttcaattc caggcgattt ttatgaaaga catgaccctg
    22021 accatctaaa gcctaaatac tataatccag aatcaaaact tcaaaaatct ggtcatggaa
    22081 gctatataga aacaacatca ggtgaagtat atttagttca tctaacatct agaccatttg
    22141 taccagagtt aaggtgtact ttaggtagag aaacagctat tcaaaaaatg aaatggacaa
    22201 aggataattg gcttcgaatg gaagatgaaa gtaatttggc aaaagaatac gtatcagaaa
    22261 gtaaactaga agaacattta gtttcatcta taccaagttt tgatgacttt gattcaaatg
    22321 aattaggttt acagtactat gctcctagga tttcaccatt atcatttgca gatgttaagt
    22381 ctagaccagg atatgtaagg attagaggac aagaatcaag aacatcatta aataaagtaa
    22441 gcatattggc aagaaaatta acttcagtat atgcaagaat aaccactaag atggagtttt
    22501 acccagaggt acatcagcat agtgcgggtt tgataatgta ttatgataat atgaattata
    22561 taaatttaag aaagtattat agtgaaacat tgggtcaaag tgcactatca ataatacatc
    22621 ttgaaaatgg agagaaaacg gaatttttaa atactaggat accaataaaa gatataccaa
    22681 tatatcttcg tctgtatata caaggtcgta agtcatattt tgaatggagt tatgatgaaa
    22741 aaaactacca gagaatagga aaggtatttg atacaactaa gttttcagat gagtactgta
    22801 aatatggaga atttacaggt acgtttatag gattaacttg tgcagatcgt gtaaagcata
    22861 aacactatgc tgattttgat ttttttgaat atatagtaga tgaatcaaaa gatgtcgatt
    22921 aataaaatca ttactaaaat tttcagagca aaggtaaatc ttatgctctg aaataagaaa
    22981 cattagaagg caaatcttac aaaaaggagt atggtattat gaatacagaa gttaatgtta
    23041 aagcaactac gattagatat gaaaagattt cattttttga aagaatttct tatggttgtg
    23101 gggatttggg gtgcaatatc atatactcag ctatgtcagc atttttgctg ttttattata
    23161 ctaattatgc agatgttagt gcagcagctg taggtagtat tatgcttgta tctaggatac
    23221 tggatgggtt tagtgactta acaatgggaa ttatagtgga tagaactaaa tccaaatacg
    23281 gtaaggctag gccttggatt ttgagaatgg cgattccttt tgctatagca gcagtattat
    23341 tattttctgt tccatcaaat cttggtatca cttctaaatt aatttatatt tttattacat
    23401 ataacttagt ttctactgtt atttatacag caatcaatgt accctatgca actctaaatt
    23461 cacttataac tcaaaaccag tatgaaagag gagtattaag tatatttaga atgatattag
    23521 ccacttgtgg taccttacta ataaatggac ttacactacc tctagttgaa tactttggaa
    23581 ataatttatc agcatggact aaaacattct ttgtatttgg aatagcatct ataatggtat
    23641 tttttataac atttactgga accaaggaaa gagtaaaagc agttaagcaa gataggaatg
    23701 aagtaatacc atttaaaata ggtattaaat ctttatttag aaataagtac tggatacaaa
    23761 taacattatg tttagtttgc atatttattg tatttgcgat aaatggtggt tcatccgtat
    23821 attatgcaaa gtttattttg ggagatgaaa aattatttgg tcctataaat atggtttcaa
    23881 atatatccca aattatagct atgtttatgg ttgctccttt tataaaaaaa tttggaaaaa
    23941 gaaatgtatt aatagtaggt tcaataatat taatatcgtc aaatgttatg tttataatag
    24001 ttggacaaaa tcatatagga gtaatatttg caagtgctat aaagggaata ggaagtgctg
    24061 gaatagcatc aacaatgttt gctattgttt cagatactat tgaatatgga gaatggaaga
    24121 ctggatatag aactgagggg cttataaata gtgcatctag ttttgggttt aaagtgggaa
    24181 atggattagg ttcagcaata ttaggtgcag tattatcaat tggtggttat gtaggaacat
    24241 cagctactca aagtgattta gctatagtat caataaaagt atgttttata tacctaccta
    24301 tatttataac aatattacaa attatcataa tgtcttttta taagcttgat aaagaatata
    24361 gtactatact taatgaatta aatactaaat aatgaaaaag tttcttataa agtcttaagt
    24421 ttaattaagg tctattgtaa atgttcccta taaaaactat tatatattta tgattattga
    24481 agaattttta gagaagcgaa taataaaaat ataagaagac tttaaatgat gaaatggttg
    24541 gttttttaga aatgatttaa taagttattg ttatttaaag cattataagt ggacaattaa
    24601 tttttaattt atggagatga tatttaacaa ttagaagtaa tatataatat gcactaagaa
    24661 gcaatttttc aactatttat gaaggtggtg gtacaagaaa agtatcacct tttttttgtt
    24721 atacaaaaaa acagttgact ttttatatga accccttcta taatgttact gaaattaagt
    24781 aaaatgattg aacaaatgta aagataattg aaaagcttga ttttggagga aagcaaatga
    24841 aaaaaattgg agacttaaga ttaatgatga agtgttgttc actttattac gaagataatt
    24901 tgaatcaaca ggaaatagca aatcaattgg gaatatcaag accaacaata tcaagaatat
    24961 taaaagaagc ttttgaacaa ggaatagtaa aaatacagat agttgatgtt ttgaaaaatg
    25021 attaccaaaa aatagagaga agtttggaga gaaaatataa attaaaagaa gtaatagtag
    25081 tagatgataa acaggatgca ctaacacaaa aacaagaact agcaagagct gtatctgaat
    25141 atttaactag agtagtaaag gaaaatgata taataggtgt ttcaatagga acaacactaa
    25201 aagaaatacc aagatatgtg gaaaaaagta actgtaaaaa tgttacattt atacctctat
    25261 taggagggat tggagacaat gaaatagata ttcatgcaaa tcaaatagcc gtaagtttag
    25321 cgagggcttt tggaggtgat tttaaattat tacatgctcc agctgttatg tctgacttgt
    25381 ctacaaaaga gaaactttgc aaagacgaaa aaattaaaga agtactagat ttaatagata
    25441 aaacaactat agcaattgtg ggtataggaa atcctatgag tttaaactca acaataatgg
    25501 cttctggata catgaatgaa gcagatatag aagatttaaa aaaatacaac tcaataggtg
    25561 caatttgttt acaagccttt gataaagaag gaaaaacttc tatacttgaa tttaatcaaa
    25621 gagtattagg agtgaaactg gaagatttaa aaaagataaa aagaacaata ggtgtcgctt
    25681 caggagatga aaaaatagag gcaataaagg catcattaaa agcgaaattt ataaatagtt
    25741 tagcaattaa tcacagttta gcacttaaat tattagaaga ttgtgactaa tagaaagata
    25801 gataaaagtt aacaggaggg aatgtatatg tcaatatcaa aagaaacatt gcttgaaatg
    25861 tataagagaa tgaatcaggc tagaaaattt gaagagaaag ttagttggtt ttttgcaaga
    25921 ggtatggttc atggaacaac tcacttatct gtaggtcaag aagcgtcaag tgtggcggct
    25981 gtaatggctt tagaaaaagg agatttagta tcattaactc atagaggaca tagtcaattt
    26041 ataggaatgg gaatagacct aaataaaatg atggctgaac ttatgggtaa agaaactgga
    26101 ttttgtaagg gaaaaggagg ctcaatgcat atagcagata ttgagtcagg taacttagga
    26161 gcaaatggag ttgtaggtgg aggtcttaca atagctccag gagctgcact tacacaacag
    26221 tataaaaaaa caggcaaaat agttttatgt agttttggtg atggagcatc aaatgaaggt
    26281 acttttcatg aaggaataaa tttatcttca atatggaaat tgccaataat attttactgt
    26341 gagaataatt tatacggtat gtcaacaagc ataaaacgtc atatgaatat agaaagtatt
    26401 gccactagag cagcttctta tggaatagaa ggaatatcaa tagatggata taacccaata
    26461 gaagtatacg aaacagtaca aaaagctgct gagaagtgta gaagaggaga aggacctgta
    26521 ttaattgaaa gtagaactta tagatggtta ggtcattcaa aatcagatgc aaatgtatat
    26581 agaacaaaag aagaaataga atcatggaaa gcaaaagacc ctattgaatt tttaaaaaat
    26641 tatcttatag aaaataatct atctaatgaa gatgaattag ataagattca agaatttgca
    26701 aagcaatcaa tagaagatgc agtagagttt gctcaaaata gcccaaatcc aaaaatagag
    26761 tctttattag aggatgtata tgcagactaa gaatggtaaa ggaggaaaat aaaaatgagt
    26821 acaagggaat taacatatgc acaagcaata aaggaagcaa tgtcagaaga aatgagaaga
    26881 gatgaaaatg taatatttat gggagaagat ataggaatat atggaggagc atttggtgta
    26941 tcagttggta tgatagatga atttggacca gaaagagtaa gggatactcc tatatcagaa
    27001 gcagctatag caggagcggc agcaggtgca gcagcaactg gcttaagacc tattatggaa
    27061 gtaatgttta tggactttgt aacaatttct atggatgcaa ttgtaaatca agcggcaaaa
    27121 atgagatata tgtttggagg aaaagcacaa gttccaatgg ttgttagatg cccaggaggt
    27181 tctggaactg gttcagcaga gcaacattca caaagtttag aagcttggtt ttgtcatgta
    27241 ccaggagtaa aagtagttgc accttctaca ccagcagatg ctaagggatt gttgaaagca
    27301 gctataagag ataataatcc agtcatattt gttgagaata aattgttata cagaaaaaaa
    27361 ggttttgtgc cagaagatga ttatgtaatt gaaattggaa aggcagatat taaaagagag
    27421 ggtactgatg ttacagtaat tacttatgga agaatgttac aaagtgttga agaagcagca
    27481 gagactctat caaaagaaaa tataaatgtt gaaattatag atttaagaac tttatatcca
    27541 ttagataaag agactatagt aaagagtgta tgtaaaactg ggagagtttt aatttgccat
    27601 gaagcagcta agactggtgg gctaggtgga gaaatatcag ccctgataac agaaagtgaa
    27661 tcatttgatt atttagatgc tccagtaaaa agaatttgtg gaaaagatgt gccaatacca
    27721 tataatccag agttagaaaa agcagttgtc ccaagagttg atgaaataga agaagcaata
    27781 aaatctttaa ttgttagata aggagggata gatatggtgg caaataaaat aaaagccaca
    27841 ccagcagcta gaagtcaggc aagaaaagac aatataaaat tagataggct gattggaagt
    27901 ggagaaaatg gaaggattca tttagtagat gtgttaaatt atttaaaaga taataaagca
    27961 aatactactc ctttagctag aagaatagca gaagatttaa atatagattt agaaactatt
    28021 gtaggtactg gatataatgg aaagataaga aagtgtgatg tggaaaaatt aactggaaaa
    28081 gaaactattg tatcaactaa tacatctaaa tctagtgaga aaaaagagct gaaaattgaa
    28141 aatgaaaatt caagaatgtt taacacagta gaaggaatat ttgaaaagcc aaatccaatg
    28201 agagctactg tagcaaaacg aatgtcagaa agttatttta gtgctcctgt atttacattc
    28261 aatatagaag tagatgctac agaattgaag gtacttagag caaagttaat cgacacagta
    28321 aaagaatcaa ctggagtaaa attaactatg acagatttaa tagtaatggc agtatctaaa
    28381 atacttccaa atcatcaagc cttaaattca gcatggacag atgagggtat atttagatat
    28441 aaagatgtaa atatagctat tgcagttggt ttagatgaag gcttatatgt tccggtagta
    28501 aaaaatgcaa acaaaaagtc tttaaaagaa atagcaaaag aaagcaaaga acttgcggaa
    28561 aaagtaaaga cagggaaact tatgccagca gaccaagaag gtaatacatt tacaataagt
    28621 aatgttggaa tgtatggtat aactacattt acacctataa taaatatgcc ttcaagtgca
    28681 atcttagggg taggtgctac acaagataag tttgttccag taaatggaga ggctaaaata
    28741 aaacctataa tgaacttatc attaacatca gaccatagag taatagatgg aacagtagct
    28801 gcaaaattct taaaagattt aaaagaattg ttagaaaatc ctttatcaat gcttgtatag
    28861 gttttgatat tttgttactg atataaatag tttgaataga ttatattatt ataattgttt
    28921 cagtaaattt aaagctttta tatattaaga attattttta acagtaacta tatgtgaata
    28981 tgatttgctt aattaaaata tatgaaaata aataggagga gagcctatgt cagtagaagt
    29041 aataatgcca aaagcaggag tagccatgga agaaggtact atagtatctt ggctaaagca
    29101 agaaggcgaa gaagtaaaga ttggagaacc tatactagaa ataacaacag ataaagttaa
    29161 tatggagata gagtcagaag gagaaggtac acttgctgta atcatacata aagaggaagg
    29221 tgaagtatta ccagtattta cagtaatagg tgtaatagca gaaaaagggg aaaatcaaga
    29281 ggaagtaaaa gctaaatatt tatctggaaa tgtttcaaaa gaagatatag ttgaagagaa
    29341 tcaaaatata gaatttaaag aagaaaaaat aaacaaaaaa gagtgtaatc atgattatga
    29401 tgtagtggta ataggaggag gacctggggg atatttatca gcattaaaag cagctctttt
    29461 aggtggaaga gttgctttag ttgaagaaaa tatactagga ggtacttgct taaatagagg
    29521 ttgtatccct acaaagactt atataaaaac agcagaaata ttagaagaaa ttgaccaatt
    29581 atcaaagaga ggtgtaaaag taactgtaga taaagaacag gacattaaga aggccataaa
    29641 atataaaaat agagtagtta aaaaacttac agctggtgtt ggcggattat taaaaagtag
    29701 agatgtagat gtgtttaatc ttaaagctag tgttaaagaa gagcataaag taattttatc
    29761 agatggaaaa gttttagata cagaaaatat aataattgct acaggttcca aagtaaggat
    29821 attacctata aaaggaatag aatcaaattt aataataact agtacagaag cattagattt
    29881 ggaaacagtg ccagaagaat tagtaataat tggtggtgga gtgattggtt gtgaatttgc
    29941 agagatattc aattcaagag gttctaaagt aactatagta gaaatggaag atagagtaat
    30001 cccaagaatg gataaagagt taagcgaatc tttaaaatat tctcttagta aaaaaggtat
    30061 aaatgtatta actaaaaaga aagtttctga atttaaagaa gaaggaaata acatattagt
    30121 gtgcattgaa ggtgaagagc caataaaagc agatttatgt ctatatgcta taggaagaga
    30181 agctaatctt tctggcatag aggacttaga tattaaaata gataaaggtt caatagttgt
    30241 aaatagtaaa atggaaacaa gtataccaag catatatgca gtaggtgatg ttactggagg
    30301 tgtaatgtta gctcatgctg cttttaaaat gggagaggta gcagcttcaa atgctctagg
    30361 tgtgaataaa gaagttgact taggtgcatt acctagttgt gtttatacaa ttccagaagt
    30421 agcatcagtt ggtattacag aagaggatgc tagaaaaaaa tataatgtaa aagttggtaa
    30481 gtttaatttt gctggaaatg gaagagcttt agcttctggt caagaacaag gatatgtgaa
    30541 ggtagtagca gatgctaaat atggagaaat tttaggtata catatgtttg gatgtggtgt
    30601 agcagaactt ataaatcatg cagcatcatt taaagcgtta gagataccta ctgatgaagc
    30661 aagtgagttg atatttggtc atccatgtac ttcagaagct ttaatggaag ctttggcaga
    30721 tgtaaatgga gaatgtttac acttacctaa aaaataaatc taaacataaa ttattaattt
    30781 aagtctatta ttaatattaa tttatatcat aaaattttaa aacacttact tagccatacc
    30841 ccttattatg caaataattt atttgcataa taaggggtat tttttatgga aaaatataga
    30901 atatagaatc cttgtagttt ttgttgtaca aaaaagatag taatataaaa taacattatc
    30961 attttagaat gatttcaatt gtaattagga aaagtgattt ttttgttttt aaaaaaagta
    31021 ttatttgtaa aatataaaaa aaaatttctt aatatttgaa taaaagaata gcttaattta
    31081 aatgttatta ctttataaaa aaataataag tacaaaaaaa acaatatatg gcatataagt
    31141 tgctatataa ataataagga gggaacaatt ataaatgagg caaagaataa aaaacttaat
    31201 tgaaaatgaa gataagaaaa atcctttaac agatgaagcg atttcaagta ggttaaatat
    31261 tcgaagagaa gatgttacct ttttgagaaa tgagttaaaa atagaagatt caagacaaag
    31321 aagaaaagtt gttttaatta aagctataaa agatatttta aaagaagaaa aaactataaa
    31381 taaaaatgat ataacaagaa gattaaacag cattgggttt acagtatcaa gatttacagt
    31441 catacaatac ttaaaagaga ttcaagattc tggtgaccta aaacttgata aagagagtga
    31501 tgataaaaaa gaagaaataa tcaataatag agaaaataaa gatatagcat ttgataaact
    31561 tataggtagt agtggtagct taagtacaat tataaaacta gccaaagcag caattcttta
    31621 tccacctcat ggtcttcata ctattattat ggggccaact ggtgttggaa agagtgagtt
    31681 agcagagtgt atgtataaat ttgcagtaga atcatccaga ttccctaaga atgcaccatt
    31741 tatagttttt aatgcagcag attattcaga gaatccacag cttttgctat cacagttatt
    31801 tggacacgtt aaaggtgctt ttacaggagc tgatgagaac aaagaaggat tagtatcaaa
    31861 ggcagatgga ggaatattgt ttatagatga aatacataga ttacctcatg aaggtcaaga
    31921 aatactattt caactgattg ataaaggtat ggtcagaaag ttaggagaaa caagactaac
    31981 acataaaata gatgtaatga ttatttcagc aacttctgag ccaatagatt ctcatttact
    32041 taatacattt aaaagacgta tacctgtaac aattgaaata ccagaattag ttgcaagacc
    32101 attaaatgag aggtttgaca ttataaataa tttcttctta atagaagctc aaagaatggg
    32161 agcaaacata catataaagt cagatgtatt aaaagctctt atgctttacg attgtatagg
    32221 taatgtaggt caacttagaa gtgatattca agtagcttgt gctaggggac tattaaacca
    32281 acttacaaac aaactaaaag aagtaaatat aagcatatca gatgtacctg gatatgtaaa
    32341 acaaggtctt ataaaaatca gaaattgtag agggaaaata gaaaattatg tagatgggga
    32401 tttaattata gactcaaatc ttcaaggtga gatagaaaag aaaaatgaag atatatatac
    32461 ttttccagat gaaatataca aacttactga aagaagacat attgatttat tggaacaagg
    32521 tttagatttt gatgttataa atagaatcat tggaggagaa ttagaaagtt gcattcaaaa
    32581 atacataaaa caagttaaaa aagtttctat tagtaacaat cttccagata taagtccaat
    32641 tgttggaaaa tatatcgtag agctaactta tgaagtaatc aaaatagcat cacaatacct
    32701 aagttcacta gaaccgaatc tacatttatg tttagcagtt cacctaaaag cagcttttga
    32761 gagattaaaa gaaggaaaag taatatcaaa tgctcatttg aaagaaataa taggaaatta
    32821 tccagtagaa tattctgtag cagaaaaggt agctcaatat ttaaaggaaa gatataacat
    32881 aaacttacca aaagaagaaa taggtataat agcaatatat tttaaaatga gtagtagaag
    32941 agatatgtct gaacaaaaaa agataggcgt acttcttatg gctcacggaa gagtagcatc
    33001 ttctgtatgt gaggttacaa ataaactatt aggaattaat cacgcaaggt atttagatat
    33061 gccatttgag aagaagccgg aagaaatgat tgaagaagct actacaataa taaaagatat
    33121 tgatgaaggt agaggtgtga ttatattagt agatatgggt tcactttcat attttggaga
    33181 tattatttct ggaaagactg gaattaatat aaggacaata tctagatttg atacattgct
    33241 ttctatagag gttatacgaa gagcagtttt accagattta acaatagacg agatagttga
    33301 tgaagttaaa ggtatagagc cacaagtaaa agaaaaggtt agtaaatgta acaatacaaa
    33361 agtagatttt agaaaaccta taattttaac attatgtatt actggattag ggggagcttg
    33421 taagataaaa aaaatcttag aggaaaatat taaaagtata actgaaaagg ttgatataga
    33481 acctataggt atgattgaat atccaagtct tgatttagag ataaaacaaa taagcaatga
    33541 taaaaatgta atcgccatag ttggaacaat tgaccctcag atagcaaata tccctttttt
    33601 tagtctagta gacataaatg ataaagcgaa gttaaatcaa ataaataacc taattgatac
    33661 aaatcaaatt ggtgaaacaa ataaaaaata tgaattatca gatttaatac ataaagaaga
    33721 tatatttgtg gatttacagg ttaaatcaaa agaagaagtt ctaaaatata tgagtaaaaa
    33781 acttagagag aaaggttatg tgacaaaaaa tttctataaa aaagtagtgg aaagagataa
    33841 cttatttcca actgaattat cagatgaaat agcaatacct cacacagatg gaatagatgt
    33901 aattaggcca gctataagta tagccatctt aaagaagcct attgtgtgga gtaaaagtaa
    33961 agtaaaaata atacttttat tagctgtaga ccaaaagtgt tttaatccat taagcactct
    34021 actctcattt atagaaacag atgaatttaa gaagataaaa aacattaaag atagagattt
    34081 tattagggag atgatattag atggagtcaa tgaaaataat tagtagcaat ttaattttta
    34141 aaaatattga agtgtctaac aatgaagatg cattaaagtt tttgggacaa cgtttgtttg
    34201 acgaacagta tgtaaaagaa agttacatac aagctgttgt agcaagagaa aaaaagtatg
    34261 ctacagggtt accaacagaa atatacggag tggcaatacc acatacagat atagtacatg
    34321 taaatgagcc aggaatagca attggaatac tgaataaacc tgtaaaattt ataatgatgg
    34381 gtacagacga tactgaaatt gatgtaaaag ttgtatttat gttagcagtg aaagagccac
    34441 aagaacaatt gcaactatta gaaaaactta tgactatatt tcaagataag aatatactaa
    34501 ataatattgt tgacttaagt gaagaaagtg tgagtgattt attaaactct aaattgaaaa
    34561 attaaacatg taaagtatat taaaaatgta aaattaaaca tgcaaagtat gttaaaaaat
    34621 ataaaaagat tattaaagat ttctaactat agatatcttt aaaataaaat aatttcaatg
    34681 ggggtgacta atgtggctaa aaagatatta gttgcatgtg gaacaggagt atgtacttca
    34741 acaattgcta taaacaaatt aaagaaagca cttcaagaca ttggtaaatt ggatatggtt
    34801 aatattacac aatgtaaagt agtagaagtt gcatcaaaag cacctgatta tgatttaata
    34861 atttgtacta cacaagtatc tagtagtata aaaacaccag tgataaatgg attacctttt
    34921 ttaactggtg tcggaatgga taaattaatc aatgatgtat tagaagagtt agaattataa
    34981 ttaaaaaaat taaggaacat ggtctctaaa atcataagtt ttagagactt aaaattaaat
    35041 aatggagggt ctttatatgg agatattaaa tttcattgtt ggtctaggtg cacaagtaat
    35101 gatgccaata ataatatgta tttttggttt gatattaggt acaaaactag gaaaatcttt
    35161 aagagctggt ttaactgtgg gagttgggtt tataggtctt aacactatta tagctttgct
    35221 aacagataat ttaggtccag ctacacaaca aatggttaag aatttagggc taagtttatc
    35281 aataatagat gtaggatggc cagcagcatc agctatagct tttgcatcaa cagtaggggc
    35341 tttaattatt ccaataggtc ttgtggtaaa tatagttatg ctaattacta atactactca
    35401 aactgttgat gtagacatat gggattactg gcattttgct tttacaggag ctttagtggc
    35461 aggtgctact caaagtgtaa tgtggggagt atttgcatca gtagcaaata tggtaattgt
    35521 attggtaatg gcagatttaa ctgctccagg tatagaggaa tatttaggta tgccaggtat
    35581 atctcttcct catggattta cacaggcatt tgttccaatt gctatagtag taaataaatt
    35641 attagaccta ataccaggta taaataagat tgagataaat gctgatacat tgcagaaaaa
    35701 atttggatta tttggagaac ctttaataat ggggtctgta ataggtgtaa taattggtat
    35761 tgctgcgaaa tatgatataa aaggaatatt acaattaggt gtaactatgg gagctgtatt
    35821 aatattaatt ccaaagatgg cagcattatt aatggaagga ttattaccag tatcagaagc
    35881 tgcacaggaa tttattgaga agagatttaa aaacagaggc aagatttata taggcttaga
    35941 ttcagcagta ggaataggtc atcctgttac attatcagtt gcactagtgt tggttccttt
    36001 gactatactt atagcagcta tattgccagg aaataaagtt ttaccatttg cagatttagc
    36061 agtaattcca tttgcacttg tattaatcgt accaattaca aagggaaatg tgtttagaac
    36121 attaataata ggaataatta taattacttc tggattatta atcgcaacta acttagctcc
    36181 attatttacc caaatggctt taaatgctag ttttaaaatg cctgaaggag caactatgat
    36241 ttcaagtatt tgtgatggtg cgaatccatt aagttgggta tttgtaaaag ttatgaacta
    36301 taaagttatt ggaggagtag tttttggagt tatagcttta ggaatggcta tttacaatag
    36361 gaatagaata ataaatgaaa ataaaaagct atctatagaa gaataaggtt aaaacaattt
    36421 tattaaggag tgtataggtt atgaaaaaat ataaatatga ttctaaaaga tacttactca
    36481 gtgttacaat accaggattt tttatgattt taatattgat ttatgcactg tttaataact
    36541 atacaaattt taatttgaat atatatagtt tgttaataat tgtctgtact tatggtatat
    36601 tcaatacttt tatatcatca agtaatccta aaaaaattat tattgatagc aaatgtatac
    36661 attttacctc atttatgact acacataagt atgaaattaa agatatagaa aagataagaa
    36721 taagagaatt ttataataaa aaaatttatg taaaaattaa tgatggaaac ctttttaaag
    36781 gtaggtattg gataagaaca aatatgttta ataatagtat agcattatat agctatttca
    36841 ttgagttgga agagtgctta tatccagatt cactaaaatt tagaaataaa aaatttgaga
    36901 ataagaacat ataaaaataa aaaattgaat tgaagcctag cttaatcttt tttgataaga
    36961 tataagtttg aactttatac taaattttta gaattttcaa tcaagacaat aacataatag
    37021 ctaagcaatt agaacacaat taagatgtat aaggcatgta tatgatgaat gggaggattt
    37081 aattaatgtt attagagaaa ttaagaaaag aagtattaca agcatcttta gaccttttaa
    37141 actataattt agtgacatta acaggaggaa atgtaagtgg gagagatgaa caaactggct
    37201 atatagcaat caccccaagt ggaatggatt atagaaatct tacaccaagt gatattgtta
    37261 tagtagatgt agatggaaat attatagatg gaaaatggaa agcatcagtg gatttatcag
    37321 accacttgta tatatataag catagagaag acataaatag tataattcat acacattcta
    37381 catactcaag ttgttttgct attttaaatg aacctataga atgtgcaagt acaactcttg
    37441 caaatgaagt agggggttca gtaccagttg caaaattttc accaccaaca tctaaaaaga
    37501 tgggaaaatg tgttattgaa gcaattggtg acaaaagagc atgtctttta gcaaatcatg
    37561 gcgtaattgc agttggtcca tctgtaggac atgctcttac agccgctgta atgttagaag
    37621 attcagcaaa agtatattac ttagcaaaat caattggcac accagtgcta ctgcctgatg
    37681 aagaaattca aagagcgaga gatgtatttt ttaatgtcta tggtcaggat aaataaatta
    37741 gataaaattt taaaagtaat atgaaaatat agatattcaa tgatattaag gagatttata
    37801 atgatataat aagtttaata gttaagaagt aaaatatgaa atgtaatagt atataaattc
    37861 atttaagact aaaaagaata agataaaata aaaaggagtc tgtatttcta tgtattactt
    37921 attaaacaaa agcacaaatc cttactttaa tttggcatta gaagaatatc tatttttaaa
    37981 tgataaatat aatgatgata ttataatcat atggagaaat gaagaatcca tttttatagg
    38041 taaaaatcaa aatccatatc aggaagtata tcatgatgtt attgaaaagg gagaaattcc
    38101 tattttaaga agaatatctg gaggaggaac tgtttatcat gacttaggta atatcaatat
    38161 gtcattcata caaaaagata ggcaacttca tgagatagat tttttggagc atactaagtt
    38221 tatgcaaaag atgctttcaa ccttaggact agatgtatct ataactgaaa gaaaagattt
    38281 atttttaaat gggaaaaaaa tttcaggctc tgcacagtct ataaaaagaa aaaattctct
    38341 ttatcatgga actcttcttt acgattcaga tttaaataaa ttaactaaat atttaaattc
    38401 aaataaagca actgaatcaa atgcaactaa atctgtttca agtaaagtta caaatattaa
    38461 gtttttactc gaaaaagata taaattactt tttagattat tgtgttgaat atttaaaatc
    38521 taatataaag aatataaaag aacttgaatt ggatgaagaa gatattaaaa gtgtatacaa
    38581 tataggagaa gataaatata aaaagataga gtggacatat ggtaaaacgc cgaaatttca
    38641 agtagtgcta ccatttaata atgaaagtaa aataaatata catgttaaca gatggaaagt
    38701 atcaaaattt tttatttctt atgatgataa tgtaattaat atggacaagt tgttagattt
    38761 gaatttcttt aaagaagaaa taaaagagag tattttagaa aattatccac attacataga
    38821 tttaatcaat ttaatatttt aatataaaac ctctaatttg ataaaattgt cttatatcaa
    38881 actagaggtt tttaatattc ttgcatatta acaaccatta caaaattgta aaattaaaaa
    38941 caacactatt gaaaaatcaa tatatattgt aataaatata tgtgtttttc attagcaaat
    39001 agacattaac tatttataca actgaaaatt taatatataa ttaatcagat ggttaaaata
    39061 aaaatattaa aagttttaat aaatgatggt taaaaataaa atacgaggtg ataccatgta
    39121 tagtgttata attgttgcag cgggaagcgg aaggagaatg aacttagata taaacaaaca
    39181 gttcataaaa ttaagagaaa aagaaattat tgctcataca attcaagttt tttatgaaaa
    39241 tataaatata gatgaaatag tggtatgtat aaaaaaagaa gaagaagatt tttttaaaga
    39301 aaatataata aataagtata actttaaaaa tataaaaata gcatatggcg gaaaagaaag
    39361 acaggactca atatataatg gtttaaaaaa attagatgaa aattgtgata tagtacttat
    39421 ccatgatgga gcaagaccat ttgtcgacca tagaataatc aatgaatcta taaaggtagc
    39481 taaagaaaaa aaggctgtgg ttgtaggtgt tccagtaagt gatactataa agatagtgtc
    39541 agatggaaca gtacaagaaa ctccagaaag aaatttgctg tgggcagcac aaacccctca
    39601 aacctttgaa tataatctca taatagatgc ttatgaacaa gcatataaga acaattatta
    39661 tggtactgat gattcaatgt tggtagaaaa tataggtcaa agtgtcacta tggtaatggg
    39721 ttcttatgaa aacataaaaa taactagtcc agaagattta aatatagcag aacaaatatt
    39781 aaatatggaa aaaagagatg aagttaacag tagaaggaga attatatgag aataggatta
    39841 ggatatgatg tacacaaatt aacagaggat agaaaactta taatcggtgg tgtagagata
    39901 ccacacgata aaggtttgtt gggtcattct gatgctgatg tattgataca tgcaataatg
    39961 gattctattt taggtgctct agcattagga gatataggga agcatttccc agatacagat
    40021 gaagaatata agggagcaga tagtatgaaa ttattagaac atgtgtataa tctaataaca
    40081 agtaaaggat ataaaattgg taatatagac agtactataa ttgctcaaag ccctaagatg
    40141 gctccatata ttgagagtat gagaagtaat atatcaaaag ttttaaacac agacattgat
    40201 aatataaaca taaaggcaac aacagaagaa ggtcttggtt ttacaggagc aaaacaggga
    40261 atagcttcac aaagtatttg tttattattg ttgacaagtc agaataatta atatattatt
    40321 agtaataagt ttaatggata tcaagtaata ggcctatata gaatatctat aatgtatgaa
    40381 tttaagtgaa attaatataa atataaaatt agctatgata aagaaatagt aaaatgatga
    40441 aatcttcaca gagagaaaac ggtggtgaga gttttcaaga ggaagtcttt gaacctgtct
    40501 tttagcttaa aggtataaaa atctttacgg taggaaccgt tatattccca aaagagagct
    40561 attcatatag ctaactagag tggtaccgcg gaaattaaac ctttcgtctc tatacttgta
    40621 tagagatgag aggtttttta tattttcagg aagttaatat tcaggaggaa tctattaatg
    40681 aaaatgtcaa aaatgtttat gccgacatta aaagaaatcc cagcagatgc tgagattaca
    40741 agccatcaat taatggttag gtcaggcatg ataaaaaaaa tgacttcagg tgtttataac
    40801 caattaccaa tggggttaag agtgttcaaa aaaattgaac aaataattag agaagaatta
    40861 aataaaaaag attgtcaaga aatactttgt gcagccttac ttccttctga attatggaaa
    40921 gagtctggaa ggtggactgc tatgggtgaa gaaatgttta gactaaaaga cagaacagaa
    40981 agagagtact gtcttgggcc aacacatgaa gaagcattca ctgatataat aagacaagaa
    41041 attacttcat ataaacaatt gccactaaac ttgtaccaaa tacaagtaaa atatagagac
    41101 gagagaagac caagatttgg tgttatgaga actaagactt ttacaatgaa ggatgcatat
    41161 agttttgatg tagatgataa aggtttagat aagtcatatc aagatatgtt tgatgcatat
    41221 gtaagtatat ttgatagatg tggattggag aatagccctg tacaggcaga ttcaggagct
    41281 ataggaggtt ctacatcagc cgaatttatg gttaagtcag aagttggtga agatgaagtt
    41341 gtattttgta gtggatgtga ttatgcagcc aatgtagaaa gagcagaatc ttgtaatcta
    41401 gcatcacaaa aagaagaaat gaaagaatta gaagaggttc atacaccagg agcagctaca
    41461 ataaaagagt tagaagaatt tttaaaaact tctccagata agtttgctaa aactttagta
    41521 tatgaggcag atggaaaaac agttgtagtc gttgtaagag gagatagaga agttaatgaa
    41581 atcaaagtat ctaatgccat aggttctgtt atagaatttg ctcttgctac agatgatgta
    41641 gtgagaaaag taactaatgc agaagtagga tttgcaggtc caataggtat aaatgctgac
    41701 tatgtattta tagataaaga aattgttgaa caaagaaaca tagttgttgg ggctaataaa
    41761 actgagtacc atataaaaaa tgctaactat ggaagagatt ttgaaggaat agttggagat
    41821 tttagaaatg ttcaagaagg cgacaagtgt atagtatgtg gtaagccact tgaaatagct
    41881 agaggtgttg aagtaggaca tatatttaaa ctaggaacta agtactcaga atctatgaat
    41941 gcaaacttca tagacaaaga tggaaaatca aagcctatag taatgggatg ttatggaata
    42001 ggtgttgaaa gaacagcagc agctataatt gaacaacata atgatgagaa aggtataata
    42061 tggcctttgt cagtagctcc ataccatgtt gtgatagttc cagcaaatat gaaaaatgaa
    42121 gaacaaatat caatagctga aaatatatat aatgatttgc aagctatggg tgtagaagtt
    42181 ttattagatg acagagatga aagaataggt gtcaaattca atgattcaga attaatagga
    42241 atacctatga ggattacagt aggtaaaaat attaatgaag gtaaagtaga atttaaactt
    42301 agacataaag aagataaaga gataattgac atagaagaaa taaatgaaaa agtaaaggca
    42361 gagtttatca ggaataatgt taggttagga taataactta aataagatat tgtatagata
    42421 atcaaagttg tactttatag acaccatttt atctatatat aaggatataa aatggtgttt
    42481 ttttataaaa caaataaatg aggaggtaat taaaatggca aaaaatgaaa aacaatttgt
    42541 tgaagaaata acaaagatgg aagatgattt tccacaatgg tacacagatg taataactaa
    42601 gactgactta gttgattatg caccagtaaa aggttttatg gttgtaaagc catatggata
    42661 tgcattatgg gaaaagatgc aagaatttat ggataaaaaa tttaaagaaa ctggacataa
    42721 aaactgttat tttccattat taataccaga gagtttatta aacaaagaag cagaacacgt
    42781 tgaaggtttt gctccagaag ttgcatgggt aacacatgga ggaaataaaa aattagaaga
    42841 aagattatgt gtaagaccta cttcagagac tataatatgt acaatgtatg cgaaatggtt
    42901 aaaatcatat agagaattac catatcttta taatcaatgg tgctcagttg ttagatggga
    42961 aaaatcaact agacctttct taagaacatc tgagttttta tggcaagaag gtcatacgtt
    43021 acatgaaaca gcagaagaag cacaagaaga aacaatacaa caattagaag tatataaagc
    43081 gctatgtgaa gaattacttg caatgccagt tgtagctggt caaaaaagtg aaagtgaaaa
    43141 atttgcaggt ggtgaaagaa catatactat agaagctatg atgcatgatg gtaaagcatt
    43201 acaatcaggt acaagtcact tcctaggtca acactttact aaggcttttg atattacttt
    43261 tgcagataga gaaggaaatt tagctaatcc atatcataca tcttggggag catctacaag
    43321 acttataggt ggacttataa tgactcatag tgataacaga ggtttagtat taccaccaag
    43381 agtagctcca attcaagttg ttatagttcc tatagctgct aaaaaaggaa atgtaatgga
    43441 gactgttgat aaaatatatg ctgatttaaa agctaaggga gtagctgtag aagttgatga
    43501 tagagataac tatacaactg gatggaaatt taatgagtgg gaaatgaaag gtgttccagt
    43561 aagagttgaa attggaccaa aagatataga aaataatcaa gctatggtat ttagaagaga
    43621 tactttagaa aaggattcta tgcctttaga aggattagct gatgctatat gtgatttatt
    43681 tgatgttata cacaatgata tgtttgaaaa agcaagaaaa catagagaag acaatacatc
    43741 tatagttgaa aatatggatg agtttagaaa agctttagaa gaaaagccag gattcataaa
    43801 gactatgtgg tgtggagatg cagaatgtga agctaagatt aaggaagaaa caggagcaac
    43861 tataagatgc ttaccttttg aacaagaaaa cttaggtcac aagtgtgtgt actgtggaaa
    43921 agaagcagat agtatggtag taatggcaaa agcttactaa aatacattta aataaaaact
    43981 ggggtagaaa gtatttaata ctttatccca gtttttttgt tttttatgag taataaaatg
    44041 tatttgtaac tatgtcataa gataagtcat agatacttat attaaaaaga atataataga
    44101 gaactatttt taataattac atattaatga aagcaaaata tttttgttat atagattttc
    44161 aataaagcaa acaataaata taaatgaata ttagtaagga gtgcttttaa tttttagaaa
    44221 ataaatgact taaaagaaag atttatgaaa ttaaaactag gattttctga tataataaac
    44281 atgtgtattt ttaaataaaa aggatattat tattagattt gattaaaaat aaacttgcaa
    44341 aacaatgtac tagtttaata ttatagttat attgaataaa atatcaggag gaagtaaaaa
    44401 tgaatgtaag agtaaggttt gcaccaagtc caacaggatt tgtacatata ggtagtttga
    44461 gaactgcttt atataactat ttatttgcaa aaaaaatggg cggagaatat atattaagag
    44521 tggaagatac agaccaaagt agattagtag aaggtgctat agagaatatg cttaatgcta
    44581 tgaaatgggc tggggtcaac catagtgaag gtgttatatt agatgatagt ggaaaagtag
    44641 tacaaaaagg agaatatggt ccatatattc aatctcaaag attagatata taccaagaat
    44701 atataaagca acttttagat agtggaaaag cttattactg tttctgtaca aaagaaagac
    44761 tggatgaagt aagagatgct caaagagcag caggagaaac agctaaatat gatggtcatt
    44821 gtaagaatct ttctaaagaa gaagtagaag cgaatataaa agcaggaata ccatatgtta
    44881 taagattaag attgccagag aatcatacaa ttaagtttac agacttagtt agaggagata
    44941 tggaatttaa tactaatgac ttagatgacc aagtattaat gaaaacagat ggatttccaa
    45001 cttatcattt tgcagtagtt gttgatgact atttgatgaa aattacacat gttataagag
    45061 gagaagaatg ggtatcatct actccaaaac atgtttattt atatgaagct tttggatggg
    45121 aagcacctgt atttgtgcat ttaccaaata tacttaataa agaaaagaaa aaattaagta
    45181 aaagacaagg tgatgtagct gttgaagact ttaagaaaaa aggatattta ccagagggat
    45241 tagtaaacta tgtagcatta gttggttggt ctcctgaaga taatcaagaa ttgtttacaa
    45301 tggaggaatt agaaaaagcc ttctctgtag aaagagtctc taaaagtggt ggagtatttg
    45361 atactgaaaa attaaattgg gttaatcagc attatataaa agatggtgat gatgcttatc
    45421 taacagactt agcaatacca tttttaatag aagatggatt tataacagaa gaagaagcta
    45481 ctaataaata tgatttctta aagagtatga tatcagtact taaagagaaa ttacaatatg
    45541 taaaagaagt tactgaacat gcaagtatat tttttggaga taaaatagag gtagaaactg
    45601 aagagggaag agagttctta agattagaac atatacctac tttaatagat gctttgagag
    45661 aaaaaataga aaaaacagag gtattaaatg ctgagtttgt tcaagctatg cttaaagaaa
    45721 tacaaaaaga gtacaaaata aaagggaaaa atttatttat gggctcaaga ataattttga
    45781 cagggcaaat gcatggtcca gatttaccaa aagtaatgga agttttagga aaagaaactt
    45841 gcttaaatag aatagcttat gtaaaaaata atatattata gtcataaaag tccgctaatt
    45901 tagaagcgga ctttttttgt gttagtattt ggtgaaaata tctgcttaag aaaatgaagg
    45961 tatttaaggt aataaattta atatataaaa agcaaagcaa aaatataaat aaaatatgaa
    46021 taataaacta ataaaatatt aagcatagaa gaagggaatc tattatttta gtttgattta
    46081 attattaagg gggtaattac tatgtatagt aatattgatg atgttaaaaa ggaattaaag
    46141 gagctatgct tagaatatgt tacaatttta gaaaaattaa aagatgaaaa aatgattaca
    46201 gaagaaactt ttgaaaagtg ctcttctcaa aaaaaaatat ttttagaaga acaatagagg
    46261 atggtaatag tattattatt atgtagtttg aaagatagta cgaaaaatga tagtaatact
    46321 attatttatt gcaattttca actataatat aatatataat gttaagaaga taatttataa
    46381 aaatacagtg aggtgatgag tgtgaaagtt tataatacat tgactagaac aaaagaagaa
    46441 tttgttccat tagaagaagg aaaggtaaaa atgtatgtgt gtggtccaac agtttataac
    46501 tatatacaca taggtaatgc aagaccattt ataatatttg atactctaag aaggtattta
    46561 gagtatagag gatatgatgt aacttatgta caaaacttta cagatgttga tgataagatt
    46621 ataaatagaa gtcatgagga gggaatatct cctgaagaag ttgcggctaa gtatataaaa
    46681 gaatattttg tagactgtga tgggctagga ataaaaagag ctactgttca tcctcaggtt
    46741 acagataata tacaacagat tatagagttt ataaaagagt tggaagataa gggatatgca
    46801 tatgcagtaa atggtgatgt atattttgat acaaataagt ttgaaggtta tggaaaactt
    46861 tcaggtcaaa aacaagaaga tttagaggca ggggctagaa ttgaggttaa tgaccaaaaa
    46921 agacatccta tggactttgt tctttggaag gcaaaaaaag aaggtgagcc aggatgggat
    46981 agcccttggg gagaaggtag accaggatgg catatagaat gttctgttat gtctaagaga
    47041 tatttaggtg aaacaattga tatacatgca ggtgggcaag atttaacatt cccacatcat
    47101 gaaaatgaaa tagctcaaag tgaagctaga agtggaaaaa cattctcaaa atactggatg
    47161 cataatggat atataaatat aaatgatgaa aagatgagta aatcaaaagg taatttcttt
    47221 acagtaagag atatatcaaa attatatgat ttagagatag taagattttt catgttatca
    47281 gcacattata gaaatccagt aaactttagt gatgagatgt taaatcaagc taaagcaggt
    47341 cttgaaagac tatataatac taaagaaaaa ttagaattta cgctaagtaa tttagtagaa
    47401 tctcctttaa cagaaaaaga agtagagctt gttaaagaat tagatgactt tagacaaaaa
    47461 ttcatagatg ctatggatga tgatgttaat acagcagacg cagtaagtgt aatatttgaa
    47521 ttagctaagt taataaattc taatgtagat gaaaattctt ctttggagtt tgctaaaaaa
    47581 tgcttagatg aatttaatga acttacagga gtattaaata ttgtaaataa gaaaaaagat
    47641 actgtattag ataaagacat tgaagaattg atacaaaaaa gaactgatgc aaagaaaaat
    47701 aaagagtttc aattagctga tgatattaga caacaattac tagatatggg aattgtatta
    47761 gaagacacaa gacaaggtgt taagtggaaa aggatataaa aatggaaaaa actgaattag
    47821 ttactatgtc accattagtt ttagcatact taggtgatac agtgtatgag acatatataa
    47881 gagaatattt aattagacag aatacacaaa gaaaagttaa tgatttgcat aaactagcta
    47941 taaagtatgt aaaagctaaa gctcaggcaa ctataattca tgaaattgaa attgagttaa
    48001 ctgaagaaga gagtaaaatt tataaaaggg gaagaaatca aaagtcaaat acttctccta
    48061 agaatgcaga tattatagac tacaaacatg caactgggtt tgaggcatta gtgggatatt
    48121 tgtatttaaa taatgaaata gagagacttc aatatattat caataaagga atcaaaatta
    48181 ttgaaagaga tatgtaaata ttaaagagtg ttgtcttaat aataagtaat aaggcaacac
    48241 tttttttata actaatgtat aataaatata tagaaattag taatgagaaa ggataaaaag
    48301 ttatgaaagt aaaattaata tcacatacac ctgaaccaga aaaagtaata gctatggcag
    48361 ctaagctatg ttattcacca gttgggacag acgaaataga aaaagactta acagatgaaa
    48421 gtatagagaa atttttaaat atgttattaa gtataggtca tgggtcaata ttagaacatg
    48481 cttcatttac attttcaata gaaggtattt caagggcttg ttcacatcaa attgttagac
    48541 atcgtatagc tagtttttca caacaaagtc aaagatatgt taaattagaa caatttgagt
    48601 acataattcc tccagaaata gaaaaaatag aaaaggcaaa agagttattt atagactcca
    48661 tgaaaaaaga ccaagagaat tatgataagt tagttgaaat attgtttgaa aatcattata
    48721 atgacctaat aaaaaacggt aaaaatgaga aaacagctaa aagacaagct gaaaagaaag
    48781 caatagaaga tgctagatac gtatttccaa atgcatgtga aacaaaaatg gtatttacta
    48841 taaatgctag aagtttgttt aatttctttg aacatagatg ctgtgaaaga gcacagtggg
    48901 aaataagaaa tttagctgtg gagatgttaa gagaggttaa aaaggttgct cctatattat
    48961 ttaaaaagac cggtccaagt tgtgtaaatg gaagttgtcc agaaggaact atgacttgtg
    49021 gagatatagt tcaagttaga gaaaaattta aggccttgta ggaggtgaat aatttggcga
    49081 gtatagaagg aagaaatccg gtaatagaag caataaaaag cgacagagaa atagataaaa
    49141 tattaattgc aaattcagct aaagaaggtt caattaagaa aataatagga atggctaaag
    49201 ataagaatat aattattcag tatgttgata aacataagct agatgaagta agtacaagtc
    49261 attcacatca aggtgtaata gcttatgcaa gtgagtataa gtattatgaa ttagatgagc
    49321 taatagattt agcaaagaat aaagatgaag acccattttt cattatatta gatgagataa
    49381 cagacccaca taatttgggt tcaataataa ggacagcaga tgcagtagga gcacatggag
    49441 ttatcattcc aaaaagaagg tctgtacaca taactcctgt agttgccaaa gcatctgctg
    49501 gagcagtaga atatatgcca gtttgcaagg taaccaatat agttaataca ataaaaagac
    49561 tcaaagaaga agggctgtgg attgctgcag ctgatatgga tggagaaact ttttataaac
    49621 aaaatcttac tggtcctctt ggtgtagtaa ttggaagtga aggttttgga atatctagat
    49681 tggttaaaca aaactgtgac tttatagtaa aaatgccaat gataggtaat gttacatctt
    49741 taaatgcatc tgtagcaggt ggaatacttt tatatgagat attcagacaa agactggata
    49801 aaagtaaata ggcatgaaaa aaaatataaa tcattactta ataatagatg gctacaatat
    49861 tataaatgcg tgggacaatt tgaaagaact ggctaaagag gacttagaag attctcgaga
    49921 aaagcttatt gatgacatta tagaattttc tgagtttatg ggttataaga ctataatagt
    49981 ttttgatgct tataatgtta aaaattctcg agaaaaagtt gaaaaaagaa aacacataac
    50041 aatagtttat acaagagaac accaaacagc agatagttat atagagaaat ttataacttc
    50101 tttatcaaag tatgatgatg taaaagtagc cactaatgac tatgcagaac agcaaatgat
    50161 tttaggaaaa ggtgctacta gaatgtctgc aagagaatta aagttagagt tagatcgttc
    50221 caagaataaa atgaaggaaa aaaatatcgg tttgaggaaa aaaattcagc gaaattggtt
    50281 ggaggaaagg ttagataaag aaacattgtc gaaacttgag aacattcgta gaaagcgttg
    50341 aaattactag gttctttaga ctataatata cctataaatt tgttttatat atgggggaga
    50401 tttacatgtt ggtagcaaaa gaaaaaagtt atgagttagt ggacaattgt cagcaggatg
    50461 agtataacat tgtattaaga gcaagtgaag gggataaaat agcactagag tacattatta
    50521 ctaaatacag aaattttgta aaggcaaaag caaagtcata ttttttaatt ggagcagata
    50581 aagaagatat aatacaagaa ggaatgatag gcctttataa ggcagttaga gattttgatg
    50641 gaagtaagac caattcattt aaatgttttg cggagatatg tataacaaga caaataataa
    50701 ctgctataaa aactgcaaca agacaaaaac atataccttt aaattcatat gtttctttga
    50761 ataaaccaat atatgatgaa gagtcagaca gaacactttt agatattata gctacaagta
    50821 tagtaacaga tccagaagag cttataatta gtaaagaaga gttaaaaaat atagaatcaa
    50881 aaatgaacga attgttaagt gacttggaat tagaagtact agaattatat ttaaatggaa
    50941 agtcatacca gtttatagcg gacaagctta aaagagatgt aaagtcaata gataacgctt
    51001 tacaaagggt taagagaaaa ttagaaaaac atcttgaaaa cagaaatgat taatagtaaa
    51061 atacttacca taagcttatt gtgagcaaaa ttaatttata tcgaaagata agggaggaaa
    51121 ttcaaaatgg ctaaagctaa atacgaaaga acaaaacctc atgttaatat agggacaata
    51181 ggacacgtag accacggtaa aactacatta acagcagcaa taacaaaaac attatatgac
    51241 agatatcaat taggagaagc agtagatttc gcaaacatag ataaagctcc agaagaaaga
    51301 gaaagaggaa tcacaatatc aacagcacac gttgagtatg aaacaccaaa tagacactat
    51361 gcacacgttg actgcccagg acatgctgac tacgttaaga acatgataac aggagcagca
    51421 caaatggatg gagcaatatt agtttgttca gcaacagatg gaccaatgcc acaaacaaga
    51481 gagcatatac tattatcaag acaagttgga gtaccatata tagtagtatt cttaaacaaa
    51541 tgtgacatgg tagatgatga agagttatta gagttagtag agatggaagt aagagattta
    51601 ttaacagaat atgatttccc aggagatgac actccaatag taagaggttc agcattaatg
    51661 gcattagaag atccaaagag tgagtgggga gataagatag tagaattatt cgagcaaata
    51721 gatgagtata taccagctcc agagagagat acagataaac cattcttaat gccagtagag
    51781 gacgtattct caatcacagg aagaggaaca gttgcaacag gaagagtgga aagaggagta
    51841 ctaaaagtac aagacgaagt agaattagta ggattaacag aagcaccaag aaaagtagta
    51901 gtaacaggag tagagatgtt cagaaaatt
//
LOCUS       DAJMZY010000018        51061 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.018, whole genome shotgun sequence.
ACCESSION   DAJMZY010000018 DAJMZY010000000
VERSION     DAJMZY010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 51061)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51061)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51061
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.018"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            <1..134
                     /locus_tag="OE968_001006"
     CDS             <1..134
                     /locus_tag="OE968_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HCP7218299.1"
                     /translation="RLNPGDSTFIKANVPHKIINPSKDTIARGYGVISPPIWPIKSK"
     gene            complement(329..1315)
                     /locus_tag="OE968_001007"
     CDS             complement(329..1315)
                     /locus_tag="OE968_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin-dependent carboxyltransferase"
                     /protein_id="HCP7218300.1"
                     /translation="MGFKVELGGFQTLIQDRGRVGYGQYGVSGCGAMDEYAHRVGNIL
                     VGNSEDEASLEVLMLGPTITFDEYTQIAVTGGDLGAKINGKEIQNWRSYQINPGDVLS
                     FRGVKSGARAYVSIAGGIDVPLAMGSKSTYTRAKIGGFEGRALKKGDYINTFIQEKDF
                     TINKKLSSKYIPTYSSEIVLRIVKGPQFDAFSNGEVEKFLSNKYKVTNEIDRMGCRLD
                     GESIKHLNGADIISDGISYGAIQVPGHGKPIIMLSDRQTSGGYTKIGNVISVDLYKLA
                     QAKPNDVVKFELVDIYEAHRLLREQEDKIQDIYKSMKNIRVVKAKVLNDIAV"
     gene            complement(1345..2040)
                     /gene="pxpB"
                     /locus_tag="OE968_001008"
     CDS             complement(1345..2040)
                     /gene="pxpB"
                     /locus_tag="OE968_001008"
                     /EC_number="3.5.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-oxoprolinase subunit PxpB"
                     /protein_id="HCP7218301.1"
                     /translation="METRYLISGDKAVVAEFGNEISEDINKKVISFMRAIEISNLKGI
                     VTEMVPTYRSLMISYNPLEIDFDSLIENLKKIEDNLESIVLPKPKIHEIPVCYDEVFG
                     IDIKNVASYNNLTVDEVIKIHTSREYLIYMLGFTPGFPYLGGMDERIATPRLEVPRTK
                     IYGGSVGIAGSQTGVYPIDSPGGWQIIGRTPLKLYDENREEQILLRAGDFIKFVPITL
                     DEFIEIEKNNLSI"
     gene            complement(2060..3280)
                     /locus_tag="OE968_001009"
     CDS             complement(2060..3280)
                     /locus_tag="OE968_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HCP7218302.1"
                     /translation="MSTKNITDKTKNKKDVGALIGAAFIMATSAIGPGFLTQTAQFTQ
                     DFGPNFSFVILITTILFIGAQVNVWRVIGVSGLRGQDIANKIIPGLGYLVAFLVALGG
                     LAFNIGNVGGAALGMNVMFNMNMTLGTVLSGLIAIFVFMSKNSNSLVDKITKFLALGM
                     IIIVGYVAISNHPPVGEAVSRMVKPENPKGLIFPIITLLGGSVGGYITFAGGHRLIDG
                     GITGEENIKEITKSSLLGILVATMMRVLLFLAILAVVSKGLQLDPENPAASAFKFSAG
                     AIGYKFFGLVLWSAAITSVIGAAYTSVSFLKTLNPFIDKYEKYFIIAFIAISTLIMAF
                     IGKPATLLILAGALNGLILPITLGIMLIASKRKDIVGDYKHPTWLLIFGLIVVLISAY
                     TGITSLSSLGALFA"
     gene            complement(3309..4100)
                     /locus_tag="OE968_001010"
     CDS             complement(3309..4100)
                     /locus_tag="OE968_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LamB/YcsF family protein"
                     /protein_id="HCP7218303.1"
                     /translation="MYKVDLNSDLGESFGTYKIGLDEEVLKYISSANIACGFHAGDPS
                     HMEKTVQLAKKNGVKIGAHPGFLDLIGFGRREMKITKQEAKDYTKYQLGALMAFASSN
                     GCNIQHVKPHGALYNMAAKDKELAMGICEAIYEVDKDIILLGLYNSEMINSAKEIGLR
                     FANEVFADRAYDNNGFLVPRNVEGAVIHDTKHAIDRVVRMVKEGTVETLTGEVIHIKA
                     DSICVHGDNPKAIEFVKEIRKRFELESIEVCPLENIEVCSSENIV"
     gene            4688..5317
                     /locus_tag="OE968_001011"
     CDS             4688..5317
                     /locus_tag="OE968_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCP7218304.1"
                     /translation="MDKNYTMPIYQKIALDIANKIYTGEIQEDSVLFGRSVLAGKYNV
                     SPETIRRSVKILEDIGVVKSIKGKGVIVLSPDKASSFIKKYRDITNISSYKSTLYNLI
                     DTKSNLENEILDTINKILDYSNRLEIINPLVPVQFTINSNCKYIGQTAAQTKFWQNTG
                     ATIVAIKRGEELIISPGPYIEFLEGDILLVVGDQHIYNSIPMFLYENEK"
     gene            complement(5431..6945)
                     /gene="glpK"
                     /locus_tag="OE968_001012"
     CDS             complement(5431..6945)
                     /gene="glpK"
                     /locus_tag="OE968_001012"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HCP7218305.1"
                     /translation="MEKKYVMALDQGTTSSRAILFNKKGEIVKIAQKEFNQIYPKAGW
                     VEHDPMEIWGSQSGVMREVIETAGIRPEEIASIGITNQRETTVVWSRYTGKPIYNAIV
                     WQCRRTSEICDELKNKGLEESIKEKTGLLIDAYFSATKVKWILDNVEGAREKAEQGEL
                     LFGTIDTWLIWNLTRGKVHVTDYSNASRTMMYNINDLEWDEDILRELDIPISMLPLVK
                     PSSYVYGHTDERMLSGAKIPIAGCAGDQQAALFGQNCVEEGTAKNTYGTGCFLLMNTG
                     SNIVKSKHGLLTTIAWGVDGKVTYALEGSIFIGGASVQWLRDELKIIESAKDSEMYAN
                     RVEDTNGVYVVPAFTGLGAPYWDMYARGSILGLTRGAKKEHIVRATLESIAYQTKDVL
                     EAMQNDSKLKLKSLKVDGGASNNNFLMQFQSDILNVDIDRPKIVETTALGAAYLAGLS
                     VGFYIGRNEITSKWSVEKEFNPNMSEEKRCKLYKGWKKAVSRALSWEKEDELDI"
     gene            7189..7731
                     /locus_tag="OE968_001013"
     CDS             7189..7731
                     /locus_tag="OE968_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCP7218306.1"
                     /translation="MPKILENVKEDILKVSRDMILEEDYSNISIRKIAQRCGISAGTV
                     YNYFNSKQEIIEYITKSEWDLLIRRIEYSNKNTEDYIKKLNIIFTEIRNFINKVHNIQ
                     YNDFLNTFETERFFEMKKHKDDFHEQLSNKVYEALEKESFFNNDKLVCNIIIKMFFSY
                     STYLHIEFEDLKPYIEKLIH"
     gene            7745..10237
                     /locus_tag="OE968_001014"
     CDS             7745..10237
                     /locus_tag="OE968_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCP7218307.1"
                     /translation="MNHNTSIKNKDSNPKIFLVLTLYLLGIFMGAIDTGIVSPARTII
                     QNSLGVNEKTGIWMITIYTLTYASVIPISGKLADKIGRKYVYLVSIFLFGSGSLICGL
                     SSLFSNFYILLIGRVIQAIGGGGIMPIATAEFGTTFPENKRGMALGLVGATYGIANIL
                     GSSIGSTILSIFGTQNWKWLFFVNLPICLIILIGGVFCIKNNKSESKEKIDKLGTLML
                     ICIIVSLLYGLMNIDFFNFKNSIQDISVYPYLLTFIVLIPIFIFIENRAKDPILSFEY
                     FLNPRILIVLILSLIVGIGMMGMVFVPQYAENALKINAGSGGYFVAILGLFAGIAAPL
                     SGRLIDKFGAKKILLLGFSVSMIGSLYLVLIALKTNTVFSVCVSLIFMGLGMGFTMGT
                     PLNYMMLSNTRLEESNSALATLSLIRSIGTSISPAIMIGFIAHAGLSVQDNIMDLVGK
                     PSTPKIVQLEELENMIDDLKSDPEMAKNLKNVSIPNMNDTSNINMDMTGGKLPKSLLN
                     KVQSADTTNITNITKEISTTMFDEKVPSIITKIQKNVQKGIDGTQSGINGIEDGENKL
                     NSGIKGVQTGIDNMVKARAGINQGIDGVKKGIAGVDKGIKGMEQGLEKQDEAIKELTT
                     AYNKIPTTEKTPTDNENNSNEQNQSNTSNSESDDTKNDSTENKNNNSSENKPNVNEQK
                     ESLNAQIQQLKKTRDDLNTKLQKNKTQKNELSKKLRSMESQKKELQSKLNNSISQKKD
                     MEKSLDTMQQQKKSLQAVLAKTQEVKTEIPKAFDKSKLDYINSIENNRTKIENTLQST
                     LNSGFKQMYITVFCVNLLAFIILLFYKENKTR"
     gene            10658..11056
                     /locus_tag="OE968_001015"
     CDS             10658..11056
                     /locus_tag="OE968_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCP7218308.1"
                     /translation="MDTLGKRIAYLRNSKKLTQRKLMDILKFENLGKYETGDRKPNCD
                     ILMSIADYFNVTTDWLLYGKEKVNVNSSVKEDKEDYLHVTNDEMTILNLYRQLNERDK
                     IKIEGILELKISEYKDLKKHSSNNNEDKMV"
     gene            complement(11273..11482)
                     /locus_tag="OE968_001016"
     CDS             complement(11273..11482)
                     /locus_tag="OE968_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218309.1"
                     /translation="MCKLDSDGVIECCRAIDDFITALSNIKSLNMERLNTLTKYSSTC
                     SILLKEGNYEGCTIVYRKMLEELKT"
     gene            complement(11514..11723)
                     /locus_tag="OE968_001017"
     CDS             complement(11514..11723)
                     /locus_tag="OE968_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCP7218310.1"
                     /translation="MDARKKWIPFLGVQVKQRLIELNMTQRELAKKIGVNENYLSAIL
                     NGRRTGKKYKSSIYQLLNIEYSEDD"
     gene            12022..12441
                     /locus_tag="OE968_001018"
     CDS             12022..12441
                     /locus_tag="OE968_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCP7218311.1"
                     /translation="MDTLGERIVYLRKAKNLKQYELEEMLGCDNLSKFERNIRKPNYE
                     ILKSIAEIFNVSVDWLLNGDNLSHKSDLICDSSSNYPLNSINSNEIKLLNNFRKLNDY
                     DKAKIEGMIELKLHEYEKEKDLGKIEYNKNKDEKIDK"
     gene            12669..13124
                     /locus_tag="OE968_001019"
     CDS             12669..13124
                     /locus_tag="OE968_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218312.1"
                     /translation="MGLRDKFAQSFARSKTMSGPEKKANEIMGKLLLKKAILPIVLMF
                     VIIIAGAMLKINSWVTLGINLVIAVGAFFYIRNSSKKYQNFKPYVGNLISLEKKGKKE
                     YVAIIKQGKLPVKLQIAYGGEDLEHVKKNQMVQISYNPDAKIAILVNRQ"
     gene            complement(13331..13591)
                     /locus_tag="OE968_001020"
     CDS             complement(13331..13591)
                     /locus_tag="OE968_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218313.1"
                     /translation="MDKLITELSSLGAIGILCALLFKNTMQEKKEDRDMYKKTVENFI
                     ELSTQQQEINKNILVQMGIMKTDVEEIKEDVTDIKGMLQNGV"
     gene            complement(13854..14207)
                     /locus_tag="OE968_001021"
     CDS             complement(13854..14207)
                     /locus_tag="OE968_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218314.1"
                     /translation="MFKFDKNKIEQIKQGRKVEMQYKDISDISIGQVKQDDDITNNFI
                     ANVEIYEMLLNQSSVNEASNISTFSVRKSGGESGMVEVYVALILRGKKTIEEVPAVIR
                     EQVRIRCKELEIPVE"
     gene            complement(14224..19545)
                     /locus_tag="OE968_001022"
     CDS             complement(14224..19545)
                     /locus_tag="OE968_001022"
                     /inference="COORDINATES: protein
                     motif:HMM:NF012632.1,HMM:NF024930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218315.1"
                     /translation="MKRTKLLQRGNFFGDKNMVVDEFDEGYDNYDFINFFTGCCNYTF
                     GLKNNNILYGCGDNSNFQLGLGEDNTTRKLFTKIPNISTNIKKVACGESHAVILTSDG
                     ELLVAGINTDGQMGLGLEKVGKTVSTFEKVPEIKGVKDIACGLQSTYLLYNDGTLYVA
                     GNNLYGQLGLGTNGASANVNTFTKVDVDNVKAVFSYNKSAFIIKNDNKCYSTGFNNQG
                     QLGLGDKNNRDLFSLVSINDVKTIACGSEHTVLMTYNNDIYGCGKEKCFGNALQSSLF
                     TKIEEVNIKTIACGHGNTMLIDNKGTLKVAGNNDIYQLGIANYSENIDNSFIDLKNIV
                     AKNIFIGLSHSILIDSNNDSYCTGDNTYGQLGSFFDDMHIVEFKKMDSEKYSYSNYIN
                     LIKSEDKLTLLKEEMEIKDIELPLDIHSVRDVVFSPYCTLVILGNGDVYGLGNNRYKG
                     MGSDLPSQLNELTKLSISNVKSIVASKNISGGIFYIKNDDTCYYSGPNSNSIAGVLPS
                     NSDVFKKISIDNVKKVVINTDLSNWFSLIVTNNKQIYTSGKSSSYVNGLSNALISQYT
                     EISLSNVTDAYSSYNATFIVVDEKKVYATGINTNYLLGFSTSDGSNVNLGLLSDWYYI
                     NISGSSYSRVSCTNNITKINNIIIYEYVTVFCTNIGSFLTGYHGTSWTKPTDSSYRVQ
                     YQGISYAGYLDSYIYNYYPTRCTQSSSSTTFAYLYNGESSSNLKNVNPDNLLISGGSS
                     YIHQYGRNYLNNQSSNNIAASNINSGPITSDKAIFLYKALLYLSSNTLYGFGNISESA
                     KELDVSDTQDGYNATNYKKVMKNIKNIFIPPYDLSRDKTRFAILTDKSLFICGYNSKG
                     THGISVNSSLNLNNKINYNKKNSSSEISSNIQEIYSHSKSTYLLTNNNMLYSVGLNDV
                     GQLGVGDEINRKVFTKINIDNIKSINVNRFTDNSKHAFAIKNDNTCYAVGLNNSGQLG
                     IGDNVNRNIFTKINVENVKYVAVYGNTSLLLTNDGLLYGAGNNGKGQLGLGDTTSRNI
                     FTRIPINGVRDVYLCNDVSIIVKNDNTCYVCGLVNGYFGFTEGSISTFTKINIENVKS
                     VVTAGSEATFFITNDNMIYTTGKKERVFFSTETNDIKGIRVINNIINAKKIVVNGYTS
                     AILTNDNKLFVGGLSGYGSIANNNNTNSVEDVKDVFVTANNTLYIDNNNNLISSGRDT
                     YGISDESYRDMSVPYYKVSIKKDVDTVFSSYNTIFIKDIYGKFYSSTGDNRYNHLGIH
                     HRYDNDKNEALEGSLHSYFKTDNTSDKIVFNKKNEKLVMFNDKYIKTNNKYINYKNIF
                     KDNFKYTSIILPFEVSDIDISKTHSLAVAKDGKLYGIGSNSYKEINQTLEDIELLTLT
                     EVNISDVKKVACGDNYSYIIKTDNTLWSYGKNTEYQLGVGHNNDVRELQKVTGLPSVK
                     DISIYNSMTLVLTNEGELYAQGYNTNGLFGLGESEKDKIIRTFTKVLTNVKEIKSHND
                     DHILVIKNDNSLWITGKNKSMYKISISITDLYEFTKIPIPEHLNDILDIELSDDTIYM
                     ITKVDTSKASIEIVEKSISQVRVVVQDPNNVIEKLEMFINDELISTKTNLEINSIIFE
                     IPQNKIVLGENKILIKASSPTGDLYSSMFIFKSETGLKVKKDSILMINNKVYSIINIT
                     ENNTDLIVTLNEGLKDDMMENNPIYQLINKTKVQVKINKSDLFKDMKLVEIKKSDSSY
                     QEIYELEEANIKSAQPKIIVEKGDKWTAIKRPSMIFRYDAENNEPQA"
     gene            complement(19562..20545)
                     /locus_tag="OE968_001023"
     CDS             complement(19562..20545)
                     /locus_tag="OE968_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HCP7218316.1"
                     /translation="MEEKFYIILTKIGREKIANATALGELVGLTKFQVGDSNGEYYEP
                     TEEQTALKNVVWEGNINSLRIDEKNPNWIVIETILPGTVGGFMIREAAVLDNENNIIA
                     IGKYPETYKPRAEDGSIKDLVVKMILQLSNTSNVTLEVDPTLVFVTQKDIQDLDDKFD
                     KNIKEIKVKIGEELLSTEAKNLSGAINEVVEKIKNISIDDVIGGQIQTELSVLKNSYN
                     KLSEKVLDILIYLELESEIDVDEAGYWYDTLTNAKNIIAIEGLKLDLNRKCITGELGS
                     VTFKNVVLPFNANRVRYIHEMDNNFVETKSNRAYSIGQTDITLNKYSYEIR"
     gene            complement(20546..21244)
                     /locus_tag="OE968_001024"
     CDS             complement(20546..21244)
                     /locus_tag="OE968_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2313 domain-containing protein"
                     /protein_id="HCP7218317.1"
                     /translation="MKLIDKLPSFDRNYIVEEIQGAYDTELNILKEDIDDTFNQLFVD
                     TATWGLDMWEDILCIEKKELDFDTRRSNIKAKMRSRGTSTIEVIKSICEAYTKSETDI
                     KVYSDEFTFVLSFIANNCDYKTLLDCSDMIERVKPAHLLHYLEPIILDKSMVYCGGGM
                     VCSEEVKVHPYFEPIIKCSAVVNCGAGMISREEIKVYPLSIKCIENNCKINIAIANDT
                     GVENVVVYPKSEVV"
     gene            complement(21241..22293)
                     /locus_tag="OE968_001025"
     CDS             complement(21241..22293)
                     /locus_tag="OE968_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate J/gp47 family protein"
                     /protein_id="HCP7218318.1"
                     /translation="MYSDQTYEVIKNRTLENINLDIYKGEGSFLNNMVSGNNLELSKI
                     YLELSKMHKMAFIQDTYNQFLDKRVNEFGVYRKLGTESNGEVEFIGEKGTVINNGTII
                     SYRDLLFVVIKDVTIGSEEGDNSPVQALEVGKKYNLPTNCEFKLVDNISGVTKITNTR
                     SFEGGTDIETDEELKERFYKIQRNQATSGNKAHYEEWALEVDGVYNVKVYPRWDGPGT
                     VKVLIFGKNNQAVDTETIERCQQHIDEEKPIGPTITVVTPLPIEISISAVMKLEDGYT
                     LDNVKESFLESINTYFRDIRGEIIYTKVMGILINTTGVHDLSNLLINGSTDNITINED
                     KIPSVTTVNFSEVENQ"
     gene            complement(22286..22714)
                     /locus_tag="OE968_001026"
     CDS             complement(22286..22714)
                     /locus_tag="OE968_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2634 domain-containing protein"
                     /protein_id="HCP7218319.1"
                     /translation="MSTIFPFIGVPEDYILPKTEELPIFREVAWDFEKDEPILEKGDF
                     KIIEKKEALKVWIYKCIKTNRYEHEIYSLEYGTELSELIGQKYTKGLTESEASRFIKE
                     ALLINPYILEVNVKSANFNRDILSANVKVSTIYGEVEINV"
     gene            complement(22714..23040)
                     /locus_tag="OE968_001027"
     CDS             complement(22714..23040)
                     /locus_tag="OE968_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2577 family protein"
                     /protein_id="HCP7218320.1"
                     /translation="MANPINEFIGIIREEGKYHNQPSFFIGKIKSKLPDLKIETNNII
                     LEKEDILIDSWMIDRQLETFDTETNQEHQHEVKNPFIDNFESGDMVIMFRIGEKFAVV
                     SKLVSL"
     gene            complement(23056..24585)
                     /locus_tag="OE968_001028"
     CDS             complement(23056..24585)
                     /locus_tag="OE968_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HCP7218321.1"
                     /translation="MIINRSKDSSSNEISFVSKDMGFLLTQSEVSYNFKDKLVEDIAK
                     QVFAENRLSVGIIAKTNVKYTKMFIGVNGYDTIMSAYTEASKKTKKKYMIEANLDKFN
                     VIEKGTVTLSVMFEEGFNIINTTFSESMENVKNKVIVVDQYGSKISEKIDNEIFKEVN
                     VIMQKVIQQQENQDVDIDSEFNGIEKSCSLKGYGDVSCITGRGVKVKDSYTKLVGLFY
                     IDTDKHTWQNGEYQIELELNFQNLMDEKSAGQDEPKEESNLGGEDYAGGKEFTAEFTA
                     YCPRKEEGGDTDCRKKKLDPSKKTCAAPMVGKYEQTYYTKEFLNKHPLLNYGDEIQVI
                     TGVSGRDGVYKVNDVGPAITIEKNGTYHIDILFGNVEEASKFGRRKGKIIIGGYSGNV
                     SDKAKIVISEAKKHLGKPYKWGGNGPSSFDCSGLMVYCFKKVNVSLPRTSNQQSKKGK
                     KVEQKNLQAGDLVFFHNPVSHVGLYIGNGEFLHAPQKGDVVKISKLSSRRDFNTARRV
                     L"
     gene            complement(24867..25289)
                     /locus_tag="OE968_001029"
     CDS             complement(24867..25289)
                     /locus_tag="OE968_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218322.1"
                     /translation="MEMWLRQAEDRFRFPVFPSSFSINGKAAVNSSSILKIGEIATFG
                     GVALKSISISSFFPNKDYTFCDYTGFPSPYDCVNKIEKWMKEGFILRFTITETNINME
                     VIIEGFSYEERDGTRDVYFTLDLKEYKRIKIPKVTPKQ"
     gene            complement(25289..27742)
                     /locus_tag="OE968_001030"
     CDS             complement(25289..27742)
                     /locus_tag="OE968_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218323.1"
                     /translation="MGNVREEGINMYLTDNYTPKMNQIISVTDNFRRATVAVSLSTNV
                     MASSIKNSIGSASNRVNSLNSSLRKVQTTASSVSSTMTKLSSSINAVSGVIGSLNGSI
                     MRLAITIAMIIDYFNKLIQKKNEFNSNIMIILIFKAKSDEVEKTKNKLLGNLKKIGGK
                     IWNIVIKAKDMTKRVISSILGKLKQVEKRPYQGSINLKDMVSSAMGRILPKLMLFKNT
                     FWSGVIAIKDMASGIISKVFPKLRLFAGKVWSGAIAVKDMASGILGSIKGKISDLTNG
                     ATIGVAVKKGVDLLGQEQNQKVVLESVMKRNTGKVNQIDVDDYYGSLVRMANDTPFDP
                     EDVVAMGTKAKMISNITGGKKEKDITQAMVDVRALNMNTSSEQDVSAAFLSAAKGNME
                     SLNTLVGENYKTFDEALEGISVKQMGLAKEMSNTIPGIISGAQTSINNGLKSIVKPFD
                     DILGQGLKKIKTFIESGLGNLAGLSEKMAGKIGNVMNGKIIIGNKYDQMQSRSVKNGK
                     EFSDSTQYRISNEAEKRKMMVENKQERFENHAATMIGNAPKAIVNAGSTLLQNIDFTA
                     LIDSLLPVVNLVNNLLDSINNKSPIAQGLISIFGTIVTTAFQLIGPVVEAVSPIITRI
                     FTFLGEYAPQINNFIETLGVIWKTVWETLGPLLETGWKIIEPILGAFFNILDKVCKIV
                     KDICKWWQTMINKIKNGSITGTVLNLVEKSKKNYKDNPYAGTKAGDSGKAYSGKKGNN
                     AFGLNYVPYNDYQTRLHEGEMVLTKQEANQYRSRKNGGNINIAKLADTIVIREEADIE
                     KITSKLVASIQLAQLGGVL"
     gene            complement(27742..27909)
                     /locus_tag="OE968_001031"
     CDS             complement(27742..27909)
                     /locus_tag="OE968_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218324.1"
                     /translation="MYYYWKKKGIRPSLFYAMDKGELKLIEAFFALEIEEEVEKMKHG
                     YGVCPLTGGGM"
     gene            complement(27936..28382)
                     /locus_tag="OE968_001032"
     CDS             complement(27936..28382)
                     /locus_tag="OE968_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HCP7218325.1"
                     /translation="MSENGLSKNINIVDLLLNSDTENLERPSTIVELKRLSTIFGQEF
                     KVMCRALTISKDEEIQNTCLKIDENMKTDIDLPEMQMLTIIEGVCDLDGKLLFKNKEL
                     MDKFKAPTPKELARKLLLPGEITNLYRILQDVMGYGKNAVIEEVKN"
     gene            complement(28496..28924)
                     /locus_tag="OE968_001033"
     CDS             complement(28496..28924)
                     /locus_tag="OE968_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tube protein"
                     /protein_id="HCP7218326.1"
                     /translation="MANMEARNVMSGTWGELWLDGNKVAEVKKFQAKMEFTKEDIIIA
                     GQMGTDTKYMGYKGKGSITLYHVSSRMHKLIGEKIKRGSEPRFVAISKLNDPDSYGAE
                     RIAVKNIAFDDLTLADWEVGVKGEIEAPFTFTEYDFLDII"
     gene            complement(28938..30002)
                     /locus_tag="OE968_001034"
     CDS             complement(28938..30002)
                     /locus_tag="OE968_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail sheath subtilisin-like
                     domain-containing protein"
                     /protein_id="HCP7218327.1"
                     /translation="MAIGLPSINISFKELATTVKERSARGIIAMVLKDAKALGLNEIH
                     EKEDIPVDLSAENKEYINLALMGNVNTPNKLLVYVIEGEADIQTALDFLETKEFNYLC
                     MPKAVEADKTAIKNWIIKLRDIDKVKVKAVLGKVVGNHEGIINFTTEDVLVGEKKYSV
                     DEFTSRVAGLIAGTPLSQSVTYTKLSDVVDIPKMTKVDAESRVNKGELILIKEAGAIR
                     IARGVNSLTELTAEKGEMFQKIKIVDTLDIIHSDIRKVIIDDYIGKVTNSYDNKCLLI
                     VAIKSYLEELEKSALIESDSTVEIDFEAQKSYLKSKGVDLSYMTLQEIKEANTGSKVF
                     LKAKIKVLDAMEDIDLSIEI"
     gene            complement(30007..30450)
                     /locus_tag="OE968_001035"
     CDS             complement(30007..30450)
                     /locus_tag="OE968_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218328.1"
                     /translation="MLKYKEILETIIEILKKNFTESIFIDDESVQGSEGSCFFVSILS
                     VICTPVMLNTNNKDIVISIKYLPKPQSKSIRMYEISDELNKLFNRNIKVTDRKLNITK
                     LEQSIKKEESIYVLNFTFTLNYLDSVYEEDVVYENMKEINLNLGE"
     gene            complement(30699..31139)
                     /locus_tag="OE968_001036"
     CDS             complement(30699..31139)
                     /locus_tag="OE968_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218329.1"
                     /translation="MENKKDILFKETDKRLHNYKYLDIKIKNINLDIKRCENEYSGCG
                     AMVYTEKTSNTYNISSSVENEVLKREERLRKLKMEKEDIEIEKEKIENALTCLNDIEM
                     EFFNLFYNSKTKNNMTYISMKLHLDRTSCYNLKKKMIFKLSEIL"
     gene            complement(31244..31441)
                     /locus_tag="OE968_001037"
     CDS             complement(31244..31441)
                     /locus_tag="OE968_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCP7218330.1"
                     /translation="MFKNNLKYYRKCKGMTQIQLARKAGITNDYISQIERGIKNPGLL
                     MAKKISSILEQNIEEVFFIQL"
     gene            31610..31930
                     /locus_tag="OE968_001038"
     CDS             31610..31930
                     /locus_tag="OE968_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HCP7218331.1"
                     /translation="MFAKRLRELRKEFGLTQRELGEKVGVSQRVLGYYETENRFPDEH
                     ILNKLADVFNVSVDYLLGRTLVKENIDTVAAHRKNPHEELPEEAQEQLNDYIEFLLNK
                     YKKK"
     gene            32012..32518
                     /locus_tag="OE968_001039"
     CDS             32012..32518
                     /locus_tag="OE968_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218332.1"
                     /translation="MNNLDKLFELASQEEIIIHYTTYIAGDLEGLYINKHGIKIISLL
                     SNLKQNSKKLTSILAEELGHHFTSLGYYVSSYNDYYTKIIIDKCENKALKWACEFLIT
                     EEDIINIINSGITCVYEMADILNVDITFFQKRLEFLSLKKQSLQLGNNKYLILTNLPY
                     FYIFDPIS"
     gene            33219..33974
                     /locus_tag="OE968_001040"
     CDS             33219..33974
                     /locus_tag="OE968_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HCP7218333.1"
                     /translation="MEKKVLATVGEKEITNIDIENALKSLDPYQAMQFKTEEGKKHLL
                     NDLVNQELFFLDAKEEKLDEEEIFKLEMKKIEENVLKQFAINKVLSSVNVTEDEKVKF
                     FEANKSSFSKPESATAKHILVDSDEKAKEILAQIKSEEISFEDAALKHSSCPSKDMGG
                     DLGTFGRGQMVPEFEEAVFSMAKGEVSEPVKTQFGYHIIKLEDLQESTESTFDEVKAE
                     VEKSLLYQKQNEVYGNKINALNAKYGNLVKYND"
     gene            complement(34117..34545)
                     /locus_tag="OE968_001041"
     CDS             complement(34117..34545)
                     /locus_tag="OE968_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HCP7218334.1"
                     /translation="MNILFFLTPKSEVAYIYEDYTIRQALEKMEYHKYSAIPIISKDG
                     KYVGTITEGDFLWTLKNDLNLDLKGLEDVPVTDINRKMDNSPVSINADIEDLVIKSLN
                     QNFIPVIDDQDTFIGIIKRRDVIGYCYEIIRGYKNLANDN"
     gene            complement(34966..35166)
                     /locus_tag="OE968_001042"
     CDS             complement(34966..35166)
                     /locus_tag="OE968_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HCP7218335.1"
                     /translation="MKTGVVKWFNNEKGFGFISVEGEGDVFVHFSAITGDGYKTLEEG
                     QSVEFEVVDGAKGPQAANVVRL"
     gene            complement(35349..36518)
                     /locus_tag="OE968_001043"
     CDS             complement(35349..36518)
                     /locus_tag="OE968_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase domain-containing protein"
                     /protein_id="HCP7218336.1"
                     /translation="MGGVALKILKNKNKYIKGIMAFVFLSLATTAGVFLINDLSMKNM
                     EEKVMESANVEGDDVKDQYKLLLENLFDYRNKAILEKNENILKGLYETDKKFGLWAYE
                     NEVKKMKYLENWSSKQGVKFKDIKTRVKIKKIKEKEKDLYGIICSVSTEYKYSYENQK
                     DKENAFRIGTYHYLNVKIIDNQYVITKEWYTDPFADSLNLENIKSDDIRNYIGQQDGV
                     ELQLTDEQKKAIDYAHKYCGAAADEEHGMKFNPNYRDYNPEGGDCANFASQIMFESGR
                     FKKNSIWNYSERAGTKAWVNAQAFKNYALYSGRGSLIAKGSYEEVYKEAYNLRPGDFV
                     GYEKKGRITHVSTVTGLDSRGYPLVTCHNTDRMLVPWDLGWSDKSIRFHIIKINY"
     gene            36754..37575
                     /locus_tag="OE968_001044"
     CDS             36754..37575
                     /locus_tag="OE968_001044"
                     /EC_number="2.7.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine kinase"
                     /protein_id="HCP7218337.1"
                     /translation="MQKKVAAINDLSGIGKCSLSVAIPILSALKVQCCPFPTAILSSQ
                     TGYPEFTFLDFTDEMVKYSNVWKNLKVNFDSIYSGFLGSKHQIEIVANFINDYPNAFI
                     VVDPVMGDNGVMYPIFTEEMRHEIKELVKHSDLTTPNLTEACFLTGNDYTKSDYNRDE
                     LIYIAKSVSDLGPSKVVITGILEDDNILNLAYDRDNDHVFFTSVKYNNCSYSGTGDIF
                     TSILCGMLVNKHDLGVAVNTATDFIYKTINYTSQFDTDRNDGVMFENFLSDLTNI"
     gene            complement(37651..39039)
                     /locus_tag="OE968_001045"
     CDS             complement(37651..39039)
                     /locus_tag="OE968_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase"
                     /protein_id="HCP7218338.1"
                     /translation="MLGGKKSNNKKVEKLRTIFIKYLSLFFIMTISIVLLLMLSFSVL
                     LSSGVILPANYAEKQFNKYKEQIISSEKVTEDIIPSIYEYGVYTLDGSLISGTFNKKE
                     SKEVWNLMRDIEERHAYSESYIKFFKKDEVFIIKYKIVSEYSSPILRAYLPKPETLGM
                     IIFSIIFFIEIVILSKVFGKKFNIEMELLKNTTEKIEQQDLDFVVESSKIYEINNVLF
                     SMDKMKLALKDSLEKQWMLEENRKEQISALAHDIKTPLTIIHGNTDLLIEINENPELL
                     EYMEYISKGVTQIEKYINTLIDISKTENGYILNKEAISMSEFIKDVLVQIEALASTKN
                     LDVEFYKQDNLPKNITIDRELLFRAIMNIISNAIDYSPSQSKLYISVSVRNKYLKFVV
                     TDCGSGFSKADLSKATEQFYTGDLSRNSKSHYGMGLYIVNNIVQKHNGILYIENSVKT
                     GGAMVTIEIPIV"
     gene            complement(39174..39932)
                     /locus_tag="OE968_001046"
     CDS             complement(39174..39932)
                     /locus_tag="OE968_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutG family
                     permease subunit"
                     /protein_id="HCP7218339.1"
                     /translation="MRQLIRIFCSDLIKLKRNFIILMHICIALMGMGLFLWYYKVSGA
                     DNILKIVAYLQVIAIAFPLLSGVVCSMFVEQEYYAGNYKHMLTTSNPKYLTLISKYII
                     LVCLGFVATLVSVLGFKFGISKAYFASSFYMISILILIGCNLFEYILHLFLSLRFGKG
                     TSIGVGIVEMLLSALLLTGLGSGIWQYFPCAWGVRFITIWSSFSSSKTVEYIKVESIK
                     AYQSTGLMCGFVTILAFVILCIWFSKWEGKKSEE"
     gene            complement(39934..40650)
                     /locus_tag="OE968_001047"
     CDS             complement(39934..40650)
                     /locus_tag="OE968_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutE/EpiE
                     family permease subunit"
                     /protein_id="HCP7218340.1"
                     /translation="MERFIRVEFQKMKGTFGMKLIWIVPVFCILLCGLGGGQNAAFNW
                     WYTTFLPGALTLISSLIVLKDEKSKYRGILPLPIEMKDVWTGKMIYCIICCFIASIIS
                     AIGVVFVGIIYKETISIGQNIIATILIILLFMWQIPLCMFLASKFGIFVTVLINMFFT
                     IVGVAVFSTTEMWYMFPYSIPSRLMAVVLHILPNGLPVPEGSEFLNNAVILPGVLISI
                     VLFVLFALATRVWFNNREVK"
     gene            complement(40652..41359)
                     /locus_tag="OE968_001048"
     CDS             complement(40652..41359)
                     /locus_tag="OE968_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic protection ABC transporter
                     ATP-binding protein"
                     /protein_id="HCP7218341.1"
                     /translation="MSNYILQVKGVSKKFKEQMAVDNISLAIKSNSIYGLLGPNGAGK
                     STLLKMITGILNPTSGKIMFEGHRWTRKDLSNIGSLIESPAIYENLTARENLKVHTTL
                     LGLPDSRIEEVLETVDLRDTFKKRSGQFSLGMKQRLGIAIALLNHPKLLILDEPTNGL
                     DPIGIEELRELIRSFPKQGITVILSSHILSEVEQVVDEIGIISNGVMGYQGEVSKEQN
                     LEKLFMKVVAENRKRGQ"
     gene            complement(41475..42011)
                     /locus_tag="OE968_001049"
     CDS             complement(41475..42011)
                     /locus_tag="OE968_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HCP7218342.1"
                     /translation="MNKIAVSFLIIATTLLSTACMDYSISAVELVDSKESAVVKKDED
                     AKEETTSKMINSKKTTKIPIEIISKDEKIVKYLQIDEESSLKDKLRLILDTLSNEYFN
                     GLDMEVEVKEKDNLVKINLIEPDKKSRVSWKDDYLNEQNIIYTINNIIKNVIQEEDNS
                     IWIEEVEIYYNGKLIELR"
     gene            complement(42113..43183)
                     /locus_tag="OE968_001050"
     CDS             complement(42113..43183)
                     /locus_tag="OE968_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HCP7218343.1"
                     /translation="MNKKLAIFAAVLLVIGIIGTTWSGILVMPSLINFGLEKEAEFKK
                     ENKLYQEKVNIDKLDIAVDNINVTIKKSSSEDVRVTTRGNNEFYKYNVTLKDKTLVVK
                     GERKYENKIKKIKNFDQLLNTSINSMFSHDYREIIIYVPNNVDINASSISSHLFVYDN
                     VASNTITYKTSYGGFSRAITENKVNRLENLNLISNNNLHLSTKSILGVKNVNIESESL
                     YISSENEDVFINNIEEYIPENVNIKEKIGRNSNYESEFYLYSDMPIAKFLDIEVPNSK
                     VRLDIPVNKYKFNCDIKSKEAIEEFNNDEEYDNDSYDYEHSEEHSNKYRNTREIKGLL
                     NKNLSNLEKEYTIKINSNSLEL"
     gene            complement(43176..44234)
                     /locus_tag="OE968_001051"
     CDS             complement(43176..44234)
                     /locus_tag="OE968_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HCP7218344.1"
                     /translation="MNLNKTEFLEILKDYLKKDFSESEVNDILRDYEEYFVDGLIEGK
                     SDMEIIASLGSPKSIAKELILQTKEKNIEEEKIINTDVLNDKFSKFKSDMKKGYSILK
                     DEAKEKYSKSKENIDGKIMNTDILNGKFSRFKSNVKKDYSILKDEAKEKYNKSKENIN
                     DKLTPSIEEGVGGLSRQVIKGLLVVLSLFLIVPAFAFVCAIVSATIALVCSLIAFVIL
                     IPFVIKFIAMVPDVMMFCIFATIAFVGLEILAWQILLFAIKLGKQLLNNYIHWIKRKN
                     IYIKANEKMEKRKKATLNDEDLNKDINEDSYNNDYYNREEESIKETDEYNDDSINFEA
                     IYKDLEDIENKKGEDKHE"
     gene            complement(44221..44553)
                     /locus_tag="OE968_001052"
     CDS             complement(44221..44553)
                     /locus_tag="OE968_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HCP7218345.1"
                     /translation="MNTQFRKGVLEICVLALISKKDMYGYEIVHNISKVIDVNEGTIY
                     PILRRLTKDLYFETYILESNEGPARKYYRITSLGKENLSNLMEEWREFVKAVEILISE
                     DEGGNELE"
     gene            44752..45873
                     /locus_tag="OE968_001053"
     CDS             44752..45873
                     /locus_tag="OE968_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactosyldiacylglycerol synthase"
                     /protein_id="HCP7218346.1"
                     /translation="MKDDKTILILTAQFGAGHISAAKAVKECIIEKYSNYNVVIQNFI
                     NASIPMMNKPMVKLYENNTKYTPGLYNYYYYFKKSFDSRHDLSHKLYTPKLSEYIADI
                     NPDLIISTFPLAAACVNNFKIKNPDINIPTLTVITDVVDSMEWVFENTDLYFVPSPEI
                     KNRFFQKGINPDSIKVTGVPVDKRFQIESKELCCDKYRLLLLGGGRGLFDIDEDFMHW
                     IDEFIEEHSNSIEITIVTGKNKKLYDNLTHKKPLKNIKVLGFVNDMYNLIRECDLMLT
                     KPGGATIFEAIQSQTPVLVKMPKVGQEIENAKFIIDKGLGMIYSDDLDLKNIFYKLVS
                     NEFDSIINFMKKNLKEFKTVIHPEKIADYISELIDNHYS"
     gene            complement(46001..47899)
                     /locus_tag="OE968_001054"
     CDS             complement(46001..47899)
                     /locus_tag="OE968_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HCP7218347.1"
                     /translation="MDSLLYVIEKDKHTNEELREILKSNKNIRFVSLMGVDLGGNATD
                     EKIPVELFLEDIDKFLESAIQTDGSSVELYNIATLNNAKVDLMPDKSCHWYVDYNMEY
                     IDEEVGLPVGTLKIPAFLIHDNKKVCSRGVLQKADKYFKKSMYEIFREYPHVINNIGI
                     DSVDDIEEIMLTAATELEFWVNTPEDKADLEKLYVSQSLKEQYWKRTHGIIRTCLEKS
                     LIILQKLGVNPEMAHKEVGGIQSSISIDGRTNHAMEQLEVSWKFSTPLQAADNELLVR
                     DVIEDVFTSHGLEVTFKAKPIHGVAGSGGHTHVGVSAKLKDGSIKNLFAPKDLKEDYL
                     SELGYGALMGLLYNYEVLNPIVTASNDGFNRLVPGFEAPVCIVTSLGHSYEIPSRNRS
                     VLVGLIRDMKNPKTVRFELRSPSPLSNTYLVIAGCYQTMLDGIKAAAKSGLSTKELEK
                     ELSKNVGEESFYLEKDRAYRDENDVFEHYSLEERNARFGIPPATVYENMKNLEIYASK
                     LKSLKQGDVFTDSIIESFKIGAIDKWQKKLKTRIIEAGIQKIRSIVKIHTKENMDALD
                     EVVWNSISDLKFNIMKDTLTRESLFTRVREAIENKDYQTASDLQIELKRSMEEIQQLY
                     MQYKKNIY"
     gene            48214..48990
                     /locus_tag="OE968_001055"
     CDS             48214..48990
                     /locus_tag="OE968_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease domain-containing protein"
                     /protein_id="HCP7218348.1"
                     /translation="MEYIIFDLEFNQGFDKKLNKTVSNEKCPFEIIQIGAIKLDSKFN
                     IIDTFNSYVKPTIYKDIHPFISRMTNIKNSDFNDSPTFPEVYNNFIKFISSQDPILCV
                     WGAGDLKELYRNINYHKLPSNSLPKSYINIQQHASKYFNNPAGKSIGLQNAISILELD
                     EKMSYHNALNDAYYTAKVFIKIYNPSIVPDIYLYTSIKPKTIRYSNKKRVDYDKLFDE
                     FRKILNRELTKDEKKIINLAYNMGKTNQFTLENVKQRKNK"
     gene            complement(49082..49834)
                     /gene="xth"
                     /locus_tag="OE968_001056"
     CDS             complement(49082..49834)
                     /gene="xth"
                     /locus_tag="OE968_001056"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HCP7218349.1"
                     /translation="MKFISWNVNGIRACVGKGFLDFFKEVDADIFCLQETKLQEGQIE
                     LDLPGYFQYWNYAERKGYSGTAIFTKKEPLKVMYGINIEEHDKEGRVITLEFEDFYFV
                     TVYTPNSQSELKRLEYRTRWEDDFIDYLTKLDNHKPVIVCGDMNVAHKEIDLKNPKNN
                     MKNAGFTKEEREKFSKLLDSGFIDTYRYFNPDKEGVYSWWSYRFNARKNNAGWRIDYF
                     CASKKLEDRLVSADIHTEILGSDHCPVELEIK"
     gene            complement(49995..50945)
                     /gene="galT"
                     /locus_tag="OE968_001057"
     CDS             complement(49995..50945)
                     /gene="galT"
                     /locus_tag="OE968_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-1-phosphate uridylyltransferase"
                     /protein_id="HCP7218350.1"
                     /translation="MKELRIDPITNDVVIFATDRLKRPLDTADIPNEDEETNEYDEEC
                     PFCKGNEAHATDALFEIESEEGWLVKSVYNKFPIIDDMARDVYGVHEVMIESDKHNRS
                     FYNMSQKEFEDVFFMYRNRFRDLSKDDKVEYVSIFKNFLRKAGASLMHPHAQILSMSF
                     IPPEITNELLVSKEYYDSNKSSLYDDLIENEISLDRRVVYNGEAFLVLIPYATKYSGE
                     VRIIFKDKIEFGELNDNNIQELSTIFEKLFKKLYNINGYMPFNLCIHTHPTKIETKSY
                     FNVHMHIIPRKYNFGGFELGTNMYVSSMSPEDLTKKLKID"
BASE COUNT        16921 a         8554 c         5626 g        19960 t
ORIGIN      
        1 ttagattaaa tccaggtgac tcaacattta taaaagctaa tgtaccacat aaaatcatca
       61 atccaagtaa agatacaata gctcgtggat atggagttat atcacctcca atttggccaa
      121 taaaatctaa ataaactcaa tatgacacac ctactttttg tagataatat aatagattta
      181 aatattgctt ttattttaaa tttaaaatat ttactcaaac taaaaaaata gctatttgac
      241 taatctaaac catcttaatt atggtaaata gtaaatagct atttgtaagt tatattataa
      301 attataataa aaattgtatt tgttaaaatt aaactgctat atcatttaat acttttgcct
      361 ttacaactct tatatttttc atactcttgt agatatcttg aatcttatct tcttgctctc
      421 tcaatagtct atgtgcttca tatatatcta caagttcaaa ttttactaca tcatttggct
      481 ttgcttgtgc taacttatac aaatctacac ttataacgtt ccctatctta gtatagccac
      541 cactagtctg tctatctgat aacattataa tcggttttcc atgaccaggt acttgtatag
      601 ctccataaga aataccatca gatataatat ctgctccatt aaggtgcttt atactctctc
      661 catctagtct acaacccatt ctatctattt cattcgtaac tttgtattta tttgataaaa
      721 atttctctac ttcaccgtta gaaaaagcat caaattgagg accttttaca attcttagta
      781 cgatttctga actataagtt ggaatatatt ttgaacttaa ttttttattt attgtaaaat
      841 ctttttcctg aataaaagta tttatataat ctcctttttt aagtgctcta ccttcaaatc
      901 caccaatttt agctcttgta taagttgact tacttcccat tgcaagtgga acatctattc
      961 caccagctat tgacacatag gctctagcac ctgatttcac acctctaaat gataatacat
     1021 cacctggatt tatttgatat gacctccagt tttgaatttc ttttccattt attttagccc
     1081 ctaaatctcc cccagttact gctatttgcg tatattcatc aaaggtaatt gtaggaccta
     1141 acattaaaac ttctaaagaa gcctcatctt cagaatttcc tactaatata tttcctactc
     1201 tatgtgcata ctcatccatt gctccacatc cagatacacc atattgacca tagccaactc
     1261 tacctctgtc ttgtattaat gtttggaaac ctcctaattc aactttgaat cccatatata
     1321 ccactccctg tactataacg atatttaaat acttaagtta tttttttcga tttctataaa
     1381 ttcatctaat gttattggaa caaattttat aaaatctcca gctctaagca aaatctgttc
     1441 ttctctattt tcatcatata attttaaagg tgtcctacca attatttgcc atccaccagg
     1501 actatcaata ggatatacac cagtctggga acctgctatt ccaacactcc caccataaat
     1561 tttagtcctt ggcacttcta atctaggtgt agctattctt tcatccatac cacctagata
     1621 tggaaatcca ggagtaaaac ctagcatata tatcaagtac tctctgcttg tgtgtatttt
     1681 tataacttca tctacagtga gattattgta gcttgcaacg tttttaatat ctataccaaa
     1741 aacctcatca taacatactg gaatctcatg tattttaggt tttggtaata ctatactttc
     1801 caaattatct tctatttttt ttaaattctc aatcaaacta tcaaaatcta tttctaatgg
     1861 attataactt atcataagtg acctatatgt tggtaccatt tctgttacaa tacctttaag
     1921 attcgatatt tctattgctc tcataaatga aattactttt ttgtttatat cttctgatat
     1981 ctcatttcca aattcagcaa ccactgcctt atcccctgat atcaagtatc tagtttccat
     2041 aaatgtcacc tcttctaaat taagcaaata aagcacctag gctgctaaga gaagttattc
     2101 ctgtatatgc agatattaaa actactatta atccaaatat taaaagccat gtaggatgct
     2161 tgtaatctcc aacaatatct tttcttttag atgctataag cataattcct aatgtgattg
     2221 gaagtatcaa tccatttaaa gctcctgcta aaattaataa agtagctggt tttcctataa
     2281 atgccattat aagtgttgat attgctataa atgctattat aaaatatttt tcatatttat
     2341 ctataaaagg atttagtgtc tttaagaaag aaactgatgt ataagcagct cctataactg
     2401 atgtaattgc agcagaccat aatacaagtc caaagaattt atatcctatt gctcctgcac
     2461 taaatttaaa agctgaagca gctggatttt ctgggtcaag ttgaagacct tttgaaacca
     2521 ctgccagtat tgctaaaaat aaaagaactc tcatcattgt ggcaactaat atacccaaaa
     2581 gagaagattt agttatttct tttatatttt cttctcctgt tattccaccg tctattaatc
     2641 tatgtcctcc agcaaaagtt atataacctc caacacttcc tccaagtaga gttattattg
     2701 ggaatatcag tccttttgga ttttctggtt ttaccattct tgatactgcc tctccaacag
     2761 gaggatgatt tgatattgct acatatccaa ctataattat cattcctaat gctaaaaatt
     2821 tagttatctt atcgactaga gaatttgaat tttttgacat aaatacaaat atggctatta
     2881 atccacttaa tacagttcct aatgtcatat tcatattaaa cattacattc ataccaagtg
     2941 cagctccacc aacatttcct atattaaaag ctaatcctcc aagagctact aaaaaagcta
     3001 ctaaataacc taatcctggt attattttat ttgctatatc ctgacctcta agtcctgata
     3061 caccaattac tctccataca tttacttgag cccctataaa aaggattgtt gtaattaaaa
     3121 ttacaaatga aaaattcggt ccaaaatctt gggtaaattg tgcagtctga gttaaaaacc
     3181 ctggtccaat tgctgatgtt gccattataa atgcagcccc tataagtgct ccgacatctt
     3241 ttttattttt agttttatct gtaatatttt ttgtactcat attttatctc cccctcatgt
     3301 tatcagtctt atactatgtt ctctgacgaa caaacttcta tgttttctaa tggacaaact
     3361 tctatacttt ctaattcaaa acgctttctt atttctttga caaactctat tgcttttgga
     3421 ttgtccccat gtacacatat agaatctgct ttgatatgta taacttcacc tgttaaagtt
     3481 tctacagttc cttcttttac catcctaaca accctatcta ttgcatgttt tgtatcatgt
     3541 ataactgctc cttctacatt tcttggaacc aaaaaaccat tattatcata agctctatct
     3601 gcaaatactt catttgcaaa cctaagtcca atttctttag cagaatttat catttcacta
     3661 ttatatagcc ccaacagtat aatatcttta tcgacttcat atatagcttc acaaatcccc
     3721 atagctaact ctttatcttt agctgccata ttgtataatg ctccatgtgg ttttacatgt
     3781 tgtatattac atccatttga acttgcaaat gccattaaag cacccaattg atattttgta
     3841 taatctttag cttcctgctt tgttattttc atctcacgtc ttccaaatcc tattaaatct
     3901 agaaaacctg gatgtgcgcc tattttcact ccattttttt tagctagctg tactgttttt
     3961 tccatatgac tagggtcacc tgcatgaaac ccacaagcta tattagctga tgaaatatat
     4021 tttaaaactt cttcatctaa accaatctta tacgttccaa aactttctcc taaatcacta
     4081 tttaaatcta ctttatacaa tttatgaccc ctccttgcta acattttgat agaataagta
     4141 gttttaattt ttaaattttg tttattttat atattgcatg aaatatttta tcacttgtat
     4201 tcaattttat ttttgcaact attctattgc atttaattaa tataatttta ccatttaagg
     4261 aatatttttg caattatttt aattgaacat tcatttgtat ttctttttca aaaaatcttt
     4321 ttaccatttt ttagttaata attaattatt ttcacttaaa ataagggctt taacctttat
     4381 ttttaaagta tttttcattt ttaatcactt tatatgcaag acagaatcat ttttcttcat
     4441 tcatttgttt ctttcatcta tataattatc attctttgta agtaaaatat ctttatattt
     4501 ttataattaa ttctttatat agttttaagt ataataaaat catgtatact aaatgcatgt
     4561 taaaatatta ttttaaaaca tgcacaatat ttgtacatat tgtagacata taaacctata
     4621 aattatacaa tagtattgtt aagattatat atttttttaa cataaatttt gtattggggg
     4681 aaaaacaatg gataaaaact atacgatgcc aatataccaa aaaatagcgt tggatattgc
     4741 aaataaaata tacacgggtg aaatacaaga ggattcagta ctatttggac gctctgtttt
     4801 ggctggtaaa tacaatgtat ctccagaaac gataagaaga tctgtcaaaa ttttagagga
     4861 cattggcgtt gttaaaagca taaagggtaa aggtgttatt gtactatctc cagacaaagc
     4921 ttcttctttt ataaaaaaat atagagatat tacaaatata tcatcatata aatcaacact
     4981 ttataattta atagatacta aatctaattt agaaaatgaa atattagata ctataaataa
     5041 aattttagac tattctaaca gacttgaaat aatcaatcct ttagtgcccg ttcagttcac
     5101 cataaattct aattgcaaat atattggtca aacagctgca caaactaaat tttggcaaaa
     5161 tacaggtgct acaatagttg caattaaaag aggtgaagaa cttataatat ctcctggacc
     5221 atatattgaa tttttagaag gagacattct cttagtagtt ggtgaccaac acatttacaa
     5281 ttctatacca atgtttttat atgaaaacga aaaataaatt atataattta gtatgattat
     5341 ataaaaatgc aaaattaaca acaaaaaaag agcttcatat tttacataaa gctcttttta
     5401 aattcaaata aatttaactt tgattaattt ttaaatatcc aattcatctt ctttttccca
     5461 gcttaaagct ctcgatacag cttttttcca tcctttatat aatttacatc tcttctcttc
     5521 actcatattt ggattaaact ctttttctac tgaccacttt gaagtaattt catttcttcc
     5581 aatatagaat ccaacagaca accctgctaa ataagcagct cctaaagctg tagtttctac
     5641 tattttgggt ctatctatat ctacatttaa tatatctgat tgaaattgca ttaaaaaatt
     5701 attattactt gctccaccat caacttttaa tgattttagt tttaattttg aatcgttttg
     5761 cattgcttct aaaacatcct ttgtctgata agcaattgat tccaatgtgg ctcttactat
     5821 atgttctttt tttgctcctc ttgtaagtcc taaaattgaa cccctagcat acatatccca
     5881 atatggagct ccaagacctg taaatgctgg cactacatat acaccattag tatcctctac
     5941 cctatttgca tacatttcac tatcttttgc agattcaatt atctttaatt catctctaag
     6001 ccattgaaca gatgctcctc caataaatat acttccttct aatgcatatg ttacttttcc
     6061 atcaactccc caagcaattg ttgtaagtaa cccatgctta gatttaacta tgttactgcc
     6121 tgtattcata agtaagaaac aacccgttcc ataagtattt tttgcagtac cttcttcaac
     6181 acaattttga ccaaataatg ctgcttgttg gtctccagca catcccgcaa taggtatttt
     6241 agctcctgat aacatgcgct catctgtatg accataaaca tagctagaag gttttactaa
     6301 tggcaacatg cttattggta tgtccaattc tcgtaatata tcctcatccc attctaaatc
     6361 atttatattg tacatcattg ttctagatgc atttgagtaa tctgttacat gtacttttcc
     6421 acgagttaaa ttccatatta accatgtatc tatagttcca aataataact ctccttgttc
     6481 tgctttttcc ctagctcctt ctacattatc taatatccat tttacttttg ttgctgaaaa
     6541 gtatgcatct attaaaagac ctgttttttc ttttattgat tcttccaatc ctttattttt
     6601 aagttcatca catatttctg acgttctcct acactgccat actattgcgt tataaatagg
     6661 tttaccagta tacctactcc aaacaaccgt agtctctctt tgattagtta tccctattga
     6721 agcaatttct tctggtctta tacctgctgt ttctataact tctctcatta ccccactttg
     6781 tgacccccat atttccatag ggtcatgctc tacccatcca gcttttggat aaatttgatt
     6841 gaactctttt tgtgcaattt tcactatttc gcctttttta ttaaatagta tagctcttga
     6901 actggttgtt ccttggtcta atgccattac atacttcttt tccatcacca tattctcctt
     6961 atcatataat atttaattta ttaaaaagaa aaatttaata tcacatattt caataaataa
     7021 tcatacttaa gtacaaattt aatataatag atatttagta agaagacact tattttctat
     7081 catatctata taataatatt atacattata gcttacatat tgattaataa attttaaagg
     7141 agtataataa acagtgttca taataatttt aataaaagag gtggtaatat gccaaagatt
     7201 ttagaaaatg taaaagaaga tatattaaaa gtgtctcggg atatgatttt agaagaagat
     7261 tactcgaata ttagcataag gaaaatagct caaaggtgtg gtataagtgc aggtacagtg
     7321 tataattact ttaattcaaa acaagaaata atagaatata tcacaaaatc tgaatgggat
     7381 ttattgataa ggcgaattga atactccaat aaaaacactg aagattacat aaaaaaacta
     7441 aacattattt ttactgaaat aagaaatttt ataaacaaag ttcataatat ccaatacaat
     7501 gactttttaa acacttttga aacagagaga ttttttgaaa tgaaaaaaca caaagacgac
     7561 tttcatgaac agctttcaaa taaagtatat gaagctttag aaaaagaaag tttttttaat
     7621 aatgacaaat tagtatgcaa tatcataata aaaatgtttt tttcatattc aacatatctt
     7681 catatagaat ttgaagattt aaaaccctat attgaaaaat taatacatta aggtggtgtt
     7741 taccttgaat cataatacta gtattaagaa caaggacagt aatccaaaaa tatttttagt
     7801 acttacactt tatctattag gtatatttat gggagctatt gatactggaa tagtatcacc
     7861 agcaagaacg attatacaaa atagccttgg agtaaatgaa aaaacgggaa tttggatgat
     7921 taccatatac acattaacat acgcttctgt aattcctatc tctggaaaat tagcagataa
     7981 aataggaaga aaatatgtgt atctagttag tatatttcta tttggtagtg gttcattaat
     8041 atgtggatta tcatcactat tttccaattt ctatatttta ttaattggtc gtgttattca
     8101 agcaattggt ggtggtggaa tcatgccaat tgctacagca gaatttggaa ctaccttccc
     8161 agaaaacaaa agaggcatgg ctttaggttt agttggggca acatatggta ttgccaatat
     8221 tttaggttca agcattggta gcacaattct aagtatattt ggaactcaaa attggaagtg
     8281 gctatttttt gtaaatcttc caatttgttt aatcatactt attggtggag ttttctgtat
     8341 taaaaacaat aagtctgaat ctaaagaaaa aatagataag cttggtacat tgatgttgat
     8401 atgtataatc gtatcactat tatatggtct tatgaatata gactttttta attttaaaaa
     8461 ttctatacaa gatatatcag tttatccata tttattgaca tttattgtac ttatacctat
     8521 tttcatattt attgaaaata gagctaaaga ccctatttta agctttgaat attttttaaa
     8581 tccgagaata ttgatagtac ttattttatc tttaattgtt ggtattggaa tgatgggtat
     8641 ggtattcgtt ccacagtatg ctgaaaatgc attaaagata aatgctggtt ctggtggata
     8701 ttttgtagct atattgggat tatttgcagg tattgctgct cctttaagcg gaagacttat
     8761 tgacaagttt ggggcaaaaa aaatactatt actaggattt tctgtatcta tgataggctc
     8821 tctttaccta gttttaattg ctctaaaaac caatactgta tttagtgtat gtgtaagttt
     8881 aatatttatg ggattaggaa tgggatttac tatgggaact cctctaaact atatgatgtt
     8941 atcaaataca agattagaag aatctaattc agcacttgca acattatcct tgatacgctc
     9001 aattggtact tcaatttctc cagctataat gattggattt atagcacatg caggattatc
     9061 tgtgcaagat aatattatgg acttagttgg aaagccctca actcctaaaa tagttcaact
     9121 tgaagaactt gaaaacatga tagatgactt aaaatcagac cctgaaatgg caaaaaattt
     9181 aaaaaatgtc tctatcccaa atatgaatga tacttcaaat ataaatatgg acatgacagg
     9241 tggcaaactt ccaaaatcct tacttaataa agttcagtca gcagatacaa ccaacattac
     9301 caatataaca aaagaaatat caacaacaat gtttgatgaa aaagttccat ctataattac
     9361 taaaatacag aaaaatgtac aaaaaggaat agatggaaca caaagtggaa taaacggtat
     9421 tgaagatggt gaaaataaac taaatagtgg tattaaagga gttcaaactg gtattgacaa
     9481 tatggtaaaa gctagagctg gtattaatca aggaatagat ggtgtaaaaa aaggtattgc
     9541 tggtgttgac aaaggtataa aaggtatgga acaaggtctt gaaaaacaag atgaggccat
     9601 caaggaactt acaactgctt ataataaaat acctactaca gaaaaaactc ctactgataa
     9661 cgaaaataac tcaaacgaac aaaaccagag taataccagt aattctgaat cagatgacac
     9721 taagaatgat tctacagaaa ataagaataa caattccagc gagaataaac caaatgtaaa
     9781 tgaacaaaaa gaaagtttaa atgctcaaat acagcaacta aaaaagacaa gagatgactt
     9841 aaatacaaag ttacaaaaaa ataaaactca aaagaacgaa ttaagtaaaa aactaagatc
     9901 aatggaatct caaaagaaag agctacaaag caagttaaat aattctataa gccaaaagaa
     9961 agacatggaa aaaagccttg atacaatgca acagcaaaaa aaatcactcc aagcagtttt
    10021 agcaaagaca caagaggtaa aaactgaaat accaaaggct tttgataaat caaaattgga
    10081 ttatataaat tccatagaaa ataatagaac aaaaatagaa aacacactac aatctactct
    10141 aaactcagga tttaaacaga tgtatataac agtattctgt gtaaatctac tagcatttat
    10201 aatattattg ttctataaag aaaataaaac tagataaaag agtgttatag tattatattg
    10261 taaatttatc ttattcttaa atattttatt ctaaagaata aattcataaa atttttgtaa
    10321 ttgattaata taaattacaa tataatacta tttttctctt aatctttttc tcttttacag
    10381 acaatcaaaa agcaatctta gtttatcgaa ataaatttat acaatctatt catacacccc
    10441 tttacattta tataacaatt aaacctattg ttatatatac aaatcaaaat aaaccatata
    10501 ttttcaacta taatatgtta aaatcatatt atgagcatat taatttaagc aaaatgtcat
    10561 ttagacttta atttagtagt tttatattat aaatttatat atttttaatt ttaaatgtca
    10621 tttagacatt actcataaaa agaaaggagt gtattttgtg gatactttag gaaaaagaat
    10681 tgcttatttg agaaactcca aaaaacttac tcagcgcaaa cttatggata ttttaaaatt
    10741 tgaaaactta ggcaagtatg aaacaggaga tagaaaacct aattgtgata tactaatgtc
    10801 aatagctgat tattttaatg ttacgactga ctggcttctc tatggtaaag agaaggtaaa
    10861 tgtcaatagt agtgtaaaag aagataaaga agattactta catgttacta atgatgaaat
    10921 gacgatatta aatctataca gacaactaaa cgaacgtgat aaaataaaaa tagaaggaat
    10981 acttgaactt aagatatctg aatataaaga cttaaaaaag cattcctcta ataataatga
    11041 agataaaatg gtttaaacat acataatttg atacgatttt acatcatcta ttaaccttct
    11101 ttttttgtag tatattacta aaatatggat attggattat ttaaaaacaa gtatagtcta
    11161 atttcaagca catttataat atttagatta tcttatccat attttagttt aagtactttg
    11221 aaaaatataa tacatctcta tgtataactt atattcctaa gaaatgcatt actcatgttt
    11281 ttaattcttc caacatcttt ctatacacaa ttgtacatcc ttcataattc ccctctttaa
    11341 gaaggattga acatgtacta gaatatttag ttaaagtatt taatctttcc atatttaagc
    11401 tttttatatt actgagtgct gtaataaaat catcaattgc tctacaacac tctataaccc
    11461 catctgaatc caatttacac acaagaatat tcacctactt tatatactat ttattaatca
    11521 tcttctgaat attctatatt aagtaattga taaattgatg atttatattt tttacctgtt
    11581 cttcttccat ttaaaatagc tgacaaatag ttttcattaa cacctatttt cttcgctaat
    11641 tccctttgag tcatatttaa ttcaataagt ctttgcttga cttgcactcc caaaaaaggt
    11701 atccattttt ttcgagcatc catttatcaa cttcctttct aagcgattta tatttacttt
    11761 tatattattt tagcttacgc accccctcta tttagtatat atttttaata tgtacacata
    11821 ttaagtatat aaatttattt aatactaaat aagatttttt gattactttg tgctaaaatt
    11881 aggatgtaaa ttcgtatcat taagttaatt ataaagtcat tttgacctta agtcaatggt
    11941 ttttatgtca ttttgacctt taatttgaaa ctatttacat cttaaaaagt ctttttgaca
    12001 ttaattgaat ggagagtgtt tatggatact ttaggagaaa gaattgttta tttgagaaaa
    12061 gcaaaaaacc ttaaacaata tgaactagaa gaaatgttgg gctgtgacaa cttaagtaaa
    12121 tttgagagaa acattagaaa accaaattat gaaatattaa aatctatagc tgagatattt
    12181 aatgtttcag tagactggct attaaatgga gataatctat cacataaatc agatttaatt
    12241 tgcgattcct cctcaaacta tccacttaat agcataaact ctaatgaaat aaagctttta
    12301 aacaatttta gaaaattaaa tgattatgat aaagctaaaa tagaaggtat gattgaatta
    12361 aaacttcatg aatatgaaaa agagaaggat ttaggaaaaa ttgagtataa caaaaataaa
    12421 gatgagaaaa tagataaata atttttatgt tgcttttgat acgattttac atcatttctt
    12481 tgttctaata tttttatttc atttattttc ttttttataa ttttatgata aaataattag
    12541 tatattttgc tttacttgaa tgtaattatt tatacaaaag tcaaacataa tataaatgta
    12601 gtaaattttt agtttcaagt aatatctcgt tattataact aaatatttat taaaattagg
    12661 aggataaaat gggcttaaga gacaaattcg cgcaatcatt tgctagatca aaaactatga
    12721 gtggccctga gaaaaaggct aatgaaataa tgggtaaatt gcttcttaag aaagctatat
    12781 tacctatcgt tttaatgttc gtgataataa tcgctggagc tatgcttaaa atcaattctt
    12841 gggttacact tggcataaat ttagttattg ctgttggtgc tttcttctac ataagaaatt
    12901 ctagtaaaaa gtatcagaac tttaaacctt atgttggcaa tttgattagt ttagagaaaa
    12961 aaggtaaaaa agagtacgtt gctattataa aacaaggtaa gttaccagtt aagttacaaa
    13021 tagcttatgg tggtgaagac cttgaacatg ttaagaaaaa tcaaatggtt caaataagtt
    13081 ataatccaga tgctaaaata gctattttgg ttaatagaca ataatttaat aaaaaaaagg
    13141 agttgtctta aaattgattt tttctaatca aatttaagct caactccttt tttaattttt
    13201 atatgttatt tttattactt tttttaatta atattttaaa tattaaatcc ttctcaataa
    13261 aatagtgaac tatctacaat actactttat cttttcctaa caatatataa tctggtgcta
    13321 ctctttcatg ttatacacca ttttgtaaca taccttttat atcagtaaca tcttccttaa
    13381 tttcctctac atctgttttc attataccca tttgaacaag tatatttttg tttatttctt
    13441 gttgttgtgt agataattct ataaaatttt ctacagtttt tttatacatg tctctatctt
    13501 cttttttctc ctgcatagta tttttaaata atagagcaca tagtatacct attgccccta
    13561 gactactcaa ttcggttatt aatttatcca ttatagcctc ctattgtcta aattttttat
    13621 acttatagct ttaatttttg ttgtattctt acatcatgca atattatatt ttcaggatta
    13681 tcaatttaat cttctgtact ttaaattgta ggtgtaattt atagattgaa taaataataa
    13741 atatatatac aagttctaat gtaacaaaaa ataagtacaa ggcttactta ttaaagttaa
    13801 gaccttgtac tttacataaa aaaaataact aatacatagt tattctaaat ttactattca
    13861 actggtattt ctaattcttt acatctaatt ctaacttgct ctctaattac tgctggtact
    13921 tcttctattg tttttttgcc tcttaaaatt aaagctacat atacttctac cattccactc
    13981 tcacctccag attttcttac actaaaagtg cttatattac ttgcttcatt gacagaactt
    14041 tgatttaaca acatctcata tatttctaca tttgctataa aattatttgt tatatcatca
    14101 tcttgcttta cttgacctat acttatgtct gaaatgtctt tatactgcat ttctactttt
    14161 ctaccttgtt tgatttgttc tattttattt ttatcgaatt taaacaattt tcacacctcc
    14221 attttaagct tgtggctcgt tgttttcagc atcatatcta aaaatcatag atggacgttt
    14281 tatagctgtc catttatctc ctttttctac tatgatttta ggctgagcac tttttatgtt
    14341 ggcttcttct aattcataga tttcttggta acttgagtct gattttttga tttcaactag
    14401 tttcatgtct ttgaataagt cagatttatt tatttttact tgaactttag ttttatttat
    14461 taattgatat ataggattgt tttccatcat atcatccttt aatccctcat ttaatgttac
    14521 tattaagtca gtgttatttt cagtaatgtt tatgattgaa tatactttat tgtttatcat
    14581 taaaatagaa tcctttttta ctttaagccc tgtttctgat ttaaatataa acatacttga
    14641 atataaatcg cctgtaggac tactggcttt aatcagtatc ttattttctc ctaatactat
    14701 tttattttgt ggtatctcaa atataatgct atttatttcc aaattagtct tagtagatat
    14761 taattcatca tttataaaca tttcaagttt ttctataaca ttattagggt cttgtactac
    14821 aactctcact tgagatattg atttttcaac tatttctata gatgctttac ttgtatctac
    14881 ttttgttatc atgtatattg tatcatctga aagctctata tctaaaatat catttagatg
    14941 ttcaggaatt ggtattttag taaattcata taaatcagta attgatatag atattttata
    15001 catagattta tttttaccag ttatccatag actattatca tttttaatta ctagtatgtg
    15061 gtcatcatta tgtgacttaa tttctttaac attagttaat actttagtaa aagttcttat
    15121 tatcttatct ttttcacttt ctcctagtcc aaataatcca tttgtattgt acccttgagc
    15181 gtacaactct ccctcattag ttaaaacaag tgtcattgag ttatatatac ttatatcttt
    15241 aacagaaggt aatccagtaa ccttttgtaa ctctcttaca tcattattgt ggccaactcc
    15301 caattggtac tcagtattct ttccatatga ccatagagta ttatctgtct taataatata
    15361 ggagtagtta tctccacaag caactttttt gacatctgat atatttactt cagtaagagt
    15421 taataattct atatcttcaa gggtttgatt aatttcttta tatgaattac ttcctattcc
    15481 atataacttg ccatccttag caacagccaa tgaatgtgtt tttgatatat caatatcaga
    15541 tacctcaaat ggcaatatta ttgaagtata cttaaaatta tctttaaata tgtttttata
    15601 atttatatac ttattatttg tttttatata cttatcatta aacattacta gcttttcatt
    15661 tttcttatta aaaactattt tatctgatgt gttatctgtt ttaaaatatg aatgtaggga
    15721 accttcaaga gcttcatttt tatcattatc atatctatgg tgaataccta aatgattata
    15781 tctattatct cctgttgaag aataaaattt tccatatata tctttaataa atatagtatt
    15841 gtaactagaa aatacagtat caacatcttt ctttatagat actttataat atggaactga
    15901 catatcccta taagattcat cagatatacc ataagtatct ctacctgatg atatcaaatt
    15961 gttattatta tctatataaa gtgtattatt agctgttaca aaaacatctt taacatcttc
    16021 cacactattt gtattattat tatttgctat acttccatat ccactaagac ctccaacaaa
    16081 tagtttattg tcatttgtta aaatggctga agtatatcca ttaactacta ttttttttgc
    16141 atttataata ttattaatta ctcgtatccc ctttatatca ttagtctctg ttgaaaagaa
    16201 taccctctct tttttccctg tagtataaat catattgtca tttgttataa aaaatgtagc
    16261 ttcacttcct gctgtcacaa cagattttac attctcaata tttatttttg taaatgtact
    16321 tatacttcct tcagtaaacc caaaatagcc atttacaagt ccacatacat agcatgtatt
    16381 atcattttta acaatgattg atacatcatt acatagatat acatctctaa caccatttat
    16441 aggtatacgt gtaaatatat tcctacttgt agtatcaccc aatcctaact gtccttttcc
    16501 attattacct gctccatata aaagaccatc attagttaat aatagagatg tgtttccata
    16561 tacagctaca tattttacat tttcaacatt tattttagta aatatatttc tatttacatt
    16621 atctcctatt cctaactgac cagaattatt taaaccaaca gcataacagg tattatcatt
    16681 ttttatcgca aatgcatgtt tactattgtc agtaaatcta tttacattta tagattttat
    16741 attatcaata tttattttag taaatacctt tctatttatc tcatctccca ctcctaattg
    16801 acctacatca tttaaaccaa cactgtaaag catattatta ttagttaata aatatgtaga
    16861 ctttgaatgg ctatatattt cttgtatatt agaagatatt tcactactgc tattcttttt
    16921 attgtaattt atcttattat ttaaatttaa actactatta actgatatac catgcgtacc
    16981 cttagagtta tatccacata taaataagct cttatcagtt aatattgcaa atctagtttt
    17041 atctctactt aaatcataag gaggtataaa tatatttttt atatttttca ttaccttttt
    17101 ataattagtg gcattatatc catcttgtgt atctgaaaca tctagttctt ttgcactttc
    17161 agatatattc ccaaaaccat atagcgtgtt agaagataaa tacaatagag ctttatataa
    17221 aaatatggct ttatcagagg taataggacc tgaatttata ttagatgctg caatattatt
    17281 agatgattga ttgttaagat aattccttcc atattgatgt atataagatg aacctccaga
    17341 aataagtaaa ttatctggat tgacattttt taaattactt gacgattccc cattatataa
    17401 ataagcaaaa gttgtagaag atgatgattg tgtacatctt gtaggataat aattatatat
    17461 ataagaatca agatatcctg catatgaaat tccctgatat tgaactctat agcttgaatc
    17521 agttggtttt gtccatgaag taccatggta tccagttaga aaagatccaa tgtttgtaca
    17581 aaatacagtt acatactcat atatgataat attattaatt ttagtaatat tattcgtgca
    17641 tgaaactcta ctataacttg accctgatat atttatataa taccaatcac ttaataaacc
    17701 tagatttaca ttagatccat cagaagtact aaaacctaac aggtaatttg tatttatacc
    17761 agttgcatat accttttttt catcaactac aataaatgtt gcattatatg aactataagc
    17821 atcagttaca ttactaaggc taatctcagt atattgactt attaatgcat tactaagtcc
    17881 attaacataa cttgaactct ttccagaagt gtatatttgc ttattattag ttacaattaa
    17941 tgaaaaccag tttgataaat cagtatttat aacaactttt tttacattat ctatagatat
    18001 tttcttaaat acatctgaat tagaaggaag aacacctgct attgagttac tatttggtcc
    18061 agaataataa caagtatcat catttttaat gtagaatatt cctccagaaa tattttttga
    18121 tgctactata gactttacat tagagatact taattttgtc aactcattta attgacttgg
    18181 taagtcagaa cccattcctt tgtatctatt atttcctaga ccatatacat ctccattccc
    18241 taaaataacc agagtacaat aaggactaaa aacgacatct cttacagaat gtatatctag
    18301 tggaagttca atatccttta tttccatttc ttcttttaat aaagttaatt tatcctcaga
    18361 tttaattaaa tttatataat tactataact atatttttca ctatccattt tcttaaattc
    18421 tacaatgtgc atatcatcaa aaaacgaacc taattgtcca taagtattat ctcctgtaca
    18481 atatgaatca ttatttgaat caattagtat gctatgtgat aaaccaatga aaatattctt
    18541 agctacaata ttttttaaat ctataaatga attatctata ttctcagagt aatttgctat
    18601 acctaactga tatatatcat tatttccagc aacctttaaa gtacctttgt tatctataag
    18661 catagtgtta ccatgaccac atgcaatagt ttttatattt acttcttcta tcttagtaaa
    18721 tagtgatgat tgaagtgcat ttccaaaaca tttttccttt ccacaaccat atatatcatt
    18781 attatacgtc attaacacag tgtgttcaga accacaagct atagtcttaa catcattaat
    18841 agaaactaaa ctaaataaat ctctattatt cttatctcct aaacctagtt gaccttgatt
    18901 attaaaacca gtagaatagc atttattgtc attctttatt ataaaagctg atttattata
    18961 tgaaaataca gcctttacat tgtcaacatc tacttttgta aatgtattta catttgcaga
    19021 tgctccatta gttcctagac ctaattgacc atacaaatta tttccagcaa catataaagt
    19081 tccatcattg tataaaagat atgttgattg aagtccacat gcaatatcct ttacgccttt
    19141 tatttctgga accttctcaa atgtagaaac tgttttccct actttttcta atcccaatcc
    19201 catttgacca tctgtattta tacctgcgac aagtaattct ccatctgaag taagtataac
    19261 tgcatgagat tctccacatg caactttttt aatattggta gatatatttg gtattttcgt
    19321 aaataatttt cttgttgtat tgtcttctcc caatccaagt tgaaagttac tattatctcc
    19381 acatccatac aagatattat tattttttag accaaatgta tagttacaac atccagtaaa
    19441 aaaattaata aagtcataat tatcataccc ttcatcaaat tcatcaacta ccatattttt
    19501 atcgccaaag aaattacctc tttgaagtag tttagttctt ttcattataa aaacctccta
    19561 attatcttat ttcatacgaa tatttattta aagttatatc tgtctgacca attgaatatg
    19621 ccctattaga ttttgtttca acaaagttat tatccatttc atgtatatat ctaactctat
    19681 ttgcattaaa tggtagcacc acattcttaa atgtaacact accaagttct ccagttatac
    19741 actttctatt taaatctaac ttaaggcctt ctatagctat tatgttttta gcattagtta
    19801 aggtatcata ccaatatcca gcttcatcta catctatttc tgactctaat tctaagtata
    19861 ttaagatatc taatactttt tcagataatt tattgtaact attttttaat acagatagtt
    19921 cagtttgtat ttgacctcct attacatcat caatagatat atttttaatt ttttctacta
    19981 cctcatttat agctcctgat aagtttttag cttctgtaga taagagttct tcgccaattt
    20041 ttacttttat ttcttttata tttttatcaa acttatcatc taaatcttga atatcctttt
    20101 gagttacaaa aaccaacgtc gggtctactt ctaatgtaac atttgaagta ttggacaatt
    20161 gtaaaatcat ttttacaacc aaatctttaa tactgccatc ttcagcacgt ggcttatacg
    20221 tctctggata cttacctata gctattatat tattctcatt atccagaaca gcagcttctc
    20281 ttatcataaa tccaccaact gttcctggta aaatagtctc tataactatc caattaggat
    20341 ttttttcatc aattcttaga gaatttatat ttccttccca aactacattc tttaaagcag
    20401 tttgttcctc tgttggctca taatattctc cattactatc tccaacttga aacttggtta
    20461 atccaacaag ctctcctagt gcagttgcat ttgctatttt ttctctacca attttggtta
    20521 atattatata aaatttttct tccaattata ccacctccga tttaggataa actactacat
    20581 tttctacacc tgtatcattt gcaatagcta tattaatctt acaattattt tcaatgcatt
    20641 taatgcttaa aggataaacc tttatttctt ctctacttat cattccagct ccacagttta
    20701 caacagcact acattttata attggttcaa agtatggatg aacttttacc tcttcactac
    20761 ataccatacc tccaccacaa tagaccatac ttttatctag tattattggt tctaaatagt
    20821 gtaataagtg agcaggtttt actctttcaa tcatatcgct acaatctaaa agagttttat
    20881 agtcacagtt atttgctata aaactcaata cgaatgtaaa ttcatcacta taaactttta
    20941 tatctgtttc tgattttgta tatgcctcac atatactttt tataacttca atagtactag
    21001 tacctctgct tctcatttta gcttttatat tgctacgtct tgtgtcaaaa tcaagttctt
    21061 ttttttcaat gcagagtatg tcttcccaca tatctaatcc ccatgttgca gtgtcaacaa
    21121 ataattggtt aaaggtatca tcaatatctt ctttaagaat atttaattct gtatcgtatg
    21181 caccttgtat ctcctctaca atgtaatttc tatcaaatga tggtagttta tcaattagct
    21241 tcattgattt tccacctcac taaaattaac agttgttaca ctaggtattt tatcttcatt
    21301 aatagttata ttatctgtac ttccatttat aagtaggtta cttaaatcgt gtacaccagt
    21361 agtatttata agtattccca ttacttttgt atagattatc tctcctctaa tatctctaaa
    21421 gtatgtattt atactttcta ggaaagattc ttttacattg tctaatgtat atccatcttc
    21481 tagtttcatt actgcactta tacttatttc tattggtaat ggtgtcacaa ctgttatagt
    21541 tggtccaata ggcttctctt catctatatg ttgctgacac ctttcaattg tttctgtatc
    21601 aacagcttga ttatttttcc caaatatcaa gaccttaact gttcccggac catcccatct
    21661 tggataaacc ttaacattat agactccatc tacttccaaa gcccattctt catagtgagc
    21721 tttatttcca cttgtagctt gatttctttg gattttataa aatctttctt ttagttcttc
    21781 atctgtctct atatctgtac caccttcaaa acttcttgtg ttagtaatct ttgttactcc
    21841 agatatatta tcaactagtt taaattcaca atttgtaggt aaattatatt tcttaccaac
    21901 ttccagagct tgaactgggc tattgtcacc ttcttcacta ccaatagtta catcttttat
    21961 tactacaaat agtaaatctc tatatgatat tattgtgcca ttatttatta cagtaccttt
    22021 ctctccaata aattcaactt ctccatttga ctctgtacct aactttctat atacaccaaa
    22081 ttcattgact cttttatcaa gaaactggtt atatgtgtct tgtataaaag ccattttatg
    22141 catctttgaa agttctagat atatcttcga aagttctaga ttatttccag ataccatgtt
    22201 gtttagaaaa gaaccttctc ctttataaat atcaagatta atattttcaa gagttctatt
    22261 ttttattact tcatatgtct ggtcactata catttatttc cacctcccca tagatagtgg
    22321 atacttttac atttgcactc aatatgtctc tgttaaagtt agcacttttt acgtttactt
    22381 ctaatatata tggatttatt agaagggcct cttttatgaa tctactagct tcactttctg
    22441 taagaccttt tgtatatttt tgtcctatta gttctgaaag ctctgtccca tattctaaag
    22501 agtatatctc atgttcatat ctatttgtct ttatacactt gtatatccaa acttttaagg
    22561 cttctttttt ttcaattatt ttaaagtcac ctttttctaa aataggttca tctttttcaa
    22621 aatcccatgc cacttcacga aagattggca attcttctgt tttaggtaag atataatcct
    22681 ctgggacacc tataaaagga aatattgtac tcattataag ctcaccaact tacttacaac
    22741 agcaaatttt tcgcctattc taaacattat taccatatcc ccagattcaa agttatctat
    22801 aaaaggattt tttacttcat gctggtgttc ttgatttgtt tctgtgtcaa atgtttctag
    22861 ctgtctatca atcatccaac tatctatcaa aatatcttct ttttctaata tgatgttatt
    22921 tgtctctatt tttaaatctg gtaatttact tttaattttt ccaataaaaa aagaaggttg
    22981 attatgatac tttccttctt ctcttattat tcctataaat tcatttattg gattagccat
    23041 tatatcacca tccttttata atactctcct agctgtgtta aaatctcttc tactacttaa
    23101 cttacttatt ttaactacat cacctttttg tggagcatgt aaaaattctc cattacctat
    23161 atataatcca acatggctga ctggattatg aaaaaatact aaatctcctg cttgaagatt
    23221 tttttgttct actttcttgc cttttttaga ttgttgattt gacgttcttg gcaaactaac
    23281 attaactttt ttaaaacaat agaccattaa accagaacag tcaaaactac ttggtccatt
    23341 tccaccccat ttataaggtt tacctagatg tttttttgct tctgatatta ctattttagc
    23401 tttatcagat acattaccag aataaccacc aataataatt tttccttttc ttcttccaaa
    23461 tttactagct tcttcaacat ttccaaataa aatatctata tggtatgttc cattcttttc
    23521 tatagttatt gcaggtccta cgtcatttac tttatagact ccatcacgac cagaaactcc
    23581 tgtaattacc tgtatttcat ctccatagtt taataaagga tgtttattta aaaactcttt
    23641 tgtataataa gtttgctcat atttaccaac cataggagca gcgcaagttt ttttagatgg
    23701 gtcaagtttt ttctttctac aatctgtatc tccaccttct tcttttctag gacagtaagc
    23761 tgtaaattct gctgtaaact cttttcctcc tgcataatct tctcccccta aattactttc
    23821 ttccttaggt tcatcctgtc ctgctgactt ttcatccata agattttgaa aattaagttc
    23881 aagctcaatt tgatattctc cattttgcca agtatgtttg tctgtatcta tataaaatag
    23941 tcctacaagc tttgtataag aatctttaac ttttactcct ctaccagtta tacaacttac
    24001 atctccataa cctttaagag aacagctttt ttctatccca ttaaactcgc tatcaatatc
    24061 tacatcttga ttttcttgtt gctgaattac tttttgcatt attacattta cttccttaaa
    24121 aatttcatta tctatttttt cgctaatctt gcttccatac tggtctacca ctattacttt
    24181 attttttaca ttttccatgc tctccgaaaa ggtggtattt ataatattaa atccctcttc
    24241 aaacataaca cttaatgtaa cagttccttt ttcaataaca ttaaacttat ctaaattggc
    24301 ctctatcata tactttttct ttgtcttttt acttgcttct gtatatgcac tcattattgt
    24361 gtcataacca tttactccta taaacatctt tgtatacttg acattggtct ttgctattat
    24421 tccaactgaa agcctatttt cagcaaatac ttgctttgct atgtcttcaa ctaacttatc
    24481 tttaaaattg tatgacactt cactttgtgt aagtaaaaat cccatatctt tagatacaaa
    24541 actaatttca ttactgcttg aatctttaga cctattaatt atcattcctc taaagagttc
    24601 tttctcatct acatagaaac agactgtact agctattggt atatcgattt gttggaaatt
    24661 tacatcaaat gatgattgta ttattgaaaa ctctagtgtc cttgatggag atttataatc
    24721 acctgaccat gataccttgt ctactatgtc agttatgtca tatatacttc cgttttttat
    24781 gtgtacccaa atcttaataa taaaaaatca cctgcctttt catttaattc tatcagcagt
    24841 tatttataac ttattatcta taatagttat tgttttggag ttacttttgg tatctttatt
    24901 cttttatact cttttaaatc taatgtaaaa tatacatctc gagtcccatc tctttcttca
    24961 taactaaacc cttcaattat gacttccata tttatatttg tttccgtaat tgtaaatctt
    25021 aatataaaac cttccttcat ccatttttct atcttattta cacaatcata tggtgatgga
    25081 aaacctgtat agtcacagaa agtatagtct ttatttggaa aaaaacttga tattgaaatg
    25141 cttttaagag ctacaccacc aaaagttgct atttcaccta ttttgagtat actagaagag
    25201 tttacagcag cttttccatt aatactaaag gaagatggaa atactggaaa tctaaatcta
    25261 tcttcagctt gtctaagcca catttccatt ataagacacc ccctaactgt gccaattgga
    25321 tacttgcaac taattttgat gttatctttt ctatatcagc ttcttctcta atcactattg
    25381 tatcagctaa cttagctatg tttatatttc caccattttt tctgcttcta tattgatttg
    25441 cttcttgttt agttaaaacc atttcacctt catggagtct ggtttgatag tcattataag
    25501 gaacatagtt caatccaaat gcattattac ctttcttacc tgaataagct ttaccagaat
    25561 caccagcctt tgttccagca tatggattat ctttgtaatt ttttttactc ttttccacta
    25621 gatttaaaac tgttcctgtg atgcttccat tttttatctt attaatcata gtttgccacc
    25681 atttacatat atctttaact attttacata ctttatctaa tatgttaaaa aaagctccca
    25741 atattggctc tataattttc catccagttt ccaacagagg tcctaaggtc tcccatacag
    25801 ttttccaaat aacacccagt gtctctataa aattgtttat ttgaggtgca tattcaccta
    25861 aaaaagtaaa aattcttgtg ataataggac taacagcttc aactacaggt ccgattagtt
    25921 ggaatgctgt agttactatt gtaccaaata tacttattaa tccttgtgca attggtgatt
    25981 tattgtttat actatctagt aaattattta ctaagtttac tactggaagt aatgaatcta
    26041 ttaatgctgt aaaatcgata ttttgtaata gtgtacttcc tgcgttaaca attgcttttg
    26101 gtgcattccc tatcattgtt gctgcatgat tttcaaaacg ttcttgctta ttttcaacca
    26161 tcattttacg cttttcagcc tcattagaaa ttcgatattg agtagaatca gaaaactctt
    26221 ttccattttt tacacttcta gattgcatct ggtcatattt gttgccaata attatcttac
    26281 cattcattac attgcctatt ttaccagcca ttttttcaga taagccagct aaattgccta
    26341 atccactttc tataaaagtt tttattttct ttagtccttg acctaaaata tcatcaaaag
    26401 gtttaacaat actcttcaag ccattgttaa tgcttgtttg agctcctgat attatacctg
    26461 gtattgtatt actcatttct ttagctaacc ccatctgctt tacacttatg ccttccaatg
    26521 cttcatcaaa agttttataa ttttctccta ccagagtatt aagagattcc atgtttcctt
    26581 ttgctgcact taagaaagct gctgatacat cttgttcact acttgtattc atatttaaag
    26641 ctctaacatc taccatagct tgagttatat ctttttcttt tttgccacca gtaatattac
    26701 taatcatttt agctttagtt cccattgcaa caacatcttc agggtcaaaa ggcgtatcat
    26761 ttgccattct tactaaactg ccataataat catcaacatc tatttgatta acttttccag
    26821 tatttctttt cattacactt tctagaacaa ctttctgatt ttgttcctga ccaagtaaat
    26881 caacaccctt tttcacagcg acacctatag tagcaccatt tgtcaaatca gatatcttcc
    26941 cttttatcga accaagtatt ccacttgcca tatcctttac agctattgca ccactccata
    27001 ccttacctgc aaataatctc aatttgggaa atactttact tataatgcca cttgccatat
    27061 cttttatagc tattacacca ctccaaaaag tatttttaaa caacattaac ttaggcaaaa
    27121 ttctacccat agcactactc accatatctt taagattaat acttccttga taaggacgtt
    27181 tctctacttg ttttaatttt cccaagatac tacttatcac tctcttagtc atatcttttg
    27241 cttttattac gatattccaa atcttgccac caatcttttt taaatttcca agtaatttat
    27301 ttttagtttt ttctacttca tcacttttag ctttaaatat taatataatc ataatatttg
    27361 aattaaactc atttttcttt tgaatcaact tattaaaata atcaataatc atagctatag
    27421 ttattgctag tctcataata cttccattta aacttccaat aactcctgaa acagcattta
    27481 tgctagaact taattttgtc atagttgaac ttacactact agcagtagtt tgaacttttc
    27541 ttaacgagga atttaaactg tttactctat tacttgcact tccaatagaa ttttttatgc
    27601 tactagccat tacattagtg gaaagtgaaa cagccacagt tgctctccta aaattatcag
    27661 ttactgatat aatttgattc atttttggtg tgtaattatc tgtaaggtac atatttatac
    27721 cttcttctct cacatttccc attacatacc acctcctgtc aaaggacaca ctccatatcc
    27781 atgtttcatt ttttcaactt cttcctcaat ttctaaggcg aaaaaagctt caataagctt
    27841 taattcgcct ttatccattg cataaaaaag ggacggtctt ataccttttt tcttccaata
    27901 atagtacatt attgtagtcc tggtatccgt ccctattagt tttttacctc ttctatcact
    27961 gcatttttac cataacccat aacatcttga agtattctat ataagttggt aatttcacct
    28021 ggtaataata attttcttgc taattctttt ggtgttggag ccttaaattt atccattagc
    28081 tccttatttt taaataaaag ctttccatcc aaatcacaaa caccttctat aattgtaagc
    28141 atctgcatct ccggtaagtc tatatccgtt ttcatatttt catcaatttt aagacaagta
    28201 ttttgtattt cttcatcttt acttattgtt aaagctctac acattacttt aaattcctgc
    28261 ccaaatatag ttgataatct cttaagttca actatagtac ttggtctttc taagttttct
    28321 gtatctgaat ttaaaagtaa atctactatg tttatatttt ttgataatcc attttcactc
    28381 attattattt gctcctttat caatcaaatt caatcaacta acttttttac ttattaacta
    28441 tctgaattta ttaagtatat acttactaaa tatcagtata aaactaaata taaaactaaa
    28501 ttatatcaag aaaatcatac tcagtaaatg tgaaaggagc ttctatctct ccttttactc
    28561 caacctccca atcagctaaa gttaaatcat caaatgctat attttttact gctattcttt
    28621 ctgctccata agaatctggg tcatttaatt ttgatatagc aacaaatcta ggttcagaac
    28681 ctctctttat cttttctcca attaacttgt gcattcttga actaacgtgg tatagagtta
    28741 ttgagccttt tcctttatat cccatatact ttgtatcagt acccatttga cctgctatta
    28801 taatatcttc ttttgtaaat tccatctttg cttgaaattt ctttacttct gctactttgt
    28861 ttccatcaag ccaaagttct ccccaagtac cactcattac atttctagct tccatatttg
    28921 ccatattaat aatcctccta tatttctatt gataaatcta tatcttccat agcatcaagt
    28981 acttttattt ttgcttttaa aaatacttta gaacctgtgt tagcttcttt tatttcttgt
    29041 aatgtcatat aagataaatc tactcctttt gattttaaat acgatttttg tgcttcaaaa
    29101 tctatttcaa cagtagaatc agattctata agtgctgatt tttctaattc ttctaaataa
    29161 ctttttatag ctactatcaa taaacatttg ttgtcataac tgttagtaac ctttcctata
    29221 tagtcatcta ttatcacctt tcttatgtca ctatgtataa tatctaaagt gtcaactatt
    29281 tttattttct ggaacatttc tcctttttct gctgttaatt cagttaaaga atttactcct
    29341 ctagcaattc ttatagctcc tgcttcttta ataagtataa gctctccttt attaaccctt
    29401 gattctgcat caactttcgt catcttaggt atatcgacta catcactaag tttagtataa
    29461 gttactgatt gacttaaagg tgtacctgct ataagtccag ccaccctgct tgtaaactca
    29521 tcaacactgt atttcttttc tccaactaac acatcttctg tagtaaaatt aattatccct
    29581 tcatgatttc ctacaacttt tcctaataca gctttaacct taaccttatc tatatctcta
    29641 agtttaatta tccaattttt tatagcagtc ttatcagctt ctactgcttt tggcatacat
    29701 agataattaa attccttagt ctctaaaaaa tctaatgcag tttgaatatc tgcttctcct
    29761 tctattacat aaactaataa tttatttgga gtgttaacat ttcccatcaa agctaaattt
    29821 atatattctt tattttcagc agataaatca actggtatat cctctttttc atgtatttca
    29881 ttaagaccta gtgccttagc atctttaagt accattgcaa ttattcctct agctgaacgt
    29941 tctttaacag ttgtagctag ctccttaaat gatatgttga tacttggtaa tcctatagcc
    30001 atactatcac tctcctaaat ttaaattgat ttctttcata ttttcatata ctacatcttc
    30061 ttcatataca ctatccagat agtttagtgt aaatgtaaag ttcaatacat aaattgactc
    30121 ttctttttta atactttgtt ctagctttgt tatatttaat tttctgtctg ttacctttat
    30181 atttctgtta aatagcttat ttaattcatc tgaaatttca tacattctaa tactctttga
    30241 ctgtggtttt ggtaagtatt ttatagagat aacaatatct ttgttattcg tatttaacat
    30301 tacaggtgta caaataactg atagtatact tacaaaaaaa caagaccctt cagagccttg
    30361 cacactttca tcatcaataa aaatactttc agtaaagttt tttttgagaa tctcaataat
    30421 tgtttctaat atttccttgt atttaagcaa ataatcacca cactatcact aaatattctt
    30481 gcttaatctg ataatcttac tataaatgat ataagtcatt tttaaatata tatctcattt
    30541 attcctgtca agtatcttct atatttttag gtaatattat tcttttcaat ctatcacctc
    30601 cttcaatatg gatttctttc acaataacat tatctcacat attttattgc ctattgttgc
    30661 aatggtgtat ataaagtgtt gtaaaattgt cctatttttt ataatatctc actcaattta
    30721 aatatcatct ttttctttaa attgtagcaa gatgttctat ctaagtgtag tttcatagaa
    30781 atatatgtca tattgttttt tgtcttacta ttataaaaaa gattaaaaaa ttccatttct
    30841 atatcattta gacacgttag agcattttct atcttctctt tttctatttc tatatcttct
    30901 ttttccattt ttaattttct taatctttcc tctcttttta acacctcatt ttccacagaa
    30961 gagcttatgt tatatgtgtt actagtcttt tctgtatata ccattgctcc acatccagag
    31021 tattcattct cacatctttt tatgtccaag ttaatattct ttatctttat atccaaatac
    31081 ttataattat gtaatctttt atctgtttct ttaaataata tatctttttt gttttccata
    31141 gtacttcccc ttttttatat acttattatt agcttcaaat ttacaataat ctctttagtg
    31201 cacagttttt tactaatctc acaactttca agaacatatt gttctataac tgtataaaaa
    31261 aaacttcttc tatattttgt tctaaaatac tagaaatctt cttagccata agaagtccag
    31321 gattttttat acctctttct atttgagata tataatcatt tgtaattcca gcctttctgg
    31381 caagttgaat ttgtgtcata cctttgcatt ttctataata tttcaagtta tttttaaaca
    31441 ttgttttata cctccattac tattaagaat attttgttct tcctcactta gattatatag
    31501 aattatttgt tctttatcaa tagattttag aaaaaaatat tcttttatat tttattagtt
    31561 ttatttttta gaacaatttg ttataatcta tacataaggt ggtgttataa tgtttgccaa
    31621 aagattaaga gaacttagaa aggaatttgg attgactcaa agagaacttg gagaaaaagt
    31681 aggcgtttcc caaagagtct tagggtacta tgaaacagaa aacagatttc ctgatgaaca
    31741 cattttaaat aaattggctg atgtatttaa tgtatcagtt gattaccttc ttggaagaac
    31801 cttagttaag gaaaatattg atacagtagc tgcacataga aaaaatccac atgaagagtt
    31861 acctgaagaa gcacaagaac aacttaatga ttatatagaa tttttactaa ataaatataa
    31921 aaaaaaataa accatatgat gagcagtcta tttttctgct cttttaatat aatttaaagg
    31981 caaacataca ttctatttta gggggatttt tatgaataat ttggataagc tttttgaatt
    32041 agcttctcaa gaagagataa taattcatta taccacttat attgcaggtg atttagaagg
    32101 actatatata aacaaacatg gtattaaaat tatatcatta ctcagtaatt taaaacaaaa
    32161 ctcaaaaaaa ttgacatcca tcttagctga agaacttgga catcatttca ctagccttgg
    32221 atactatgta tcctcttata acgattatta tacaaaaatt attatagata agtgcgaaaa
    32281 taaagcctta aaatgggctt gtgagttctt aattactgaa gaagatataa taaacataat
    32341 taactctggc atcacttgcg tttatgaaat ggcagacata cttaatgtgg atattacttt
    32401 ctttcaaaaa agattagaat ttctatcatt aaaaaaacag tctttacaac ttggaaataa
    32461 taaatattta atattaacta atttgccgta tttctacata tttgatccaa tttcataata
    32521 aaaatagtag taattttaac tggcttaaca gtaaaatcta tatatttatt ttaacaaatt
    32581 ttggtttcta taaattcaat attaatatat aataatgata tcatattatt taaaattcta
    32641 aaaacaaata tatgcttttg ttaagaaagg ttgtttgatg aatgtataaa gaaaagttgt
    32701 ttgataatta ttttaagttc ttagcactat tattttggcc aattatgtgg tataagtgga
    32761 tagtaatttc aaatggtact cttgaaaata tgttatttac catatatgca atcgtcgcaa
    32821 ttgttttcat cattttatat tcggtgttta tgataaaata taaagacatt acacaaatag
    32881 atttctttta caggataagt actctacttg cttttatatt tacacttttt agctttttaa
    32941 tatacccaaa gagtttattt ttcttgtatt taaagattat ttttactgga atataccttt
    33001 attattcaat agtaaaaact cttaaattta aagatgacga aggtgtagtg ggtattatga
    33061 gctcactttt attaattgta ataactttgt tctactaaat ttaattctat ttgacttaat
    33121 atggctttaa atattagaca tctacattat tttctgatat tatttaagat ggtagtctta
    33181 tattaataat gaaatacact atgaaggagt taactattat ggaaaaaaaa gttttagcaa
    33241 cagttggaga aaaagagata actaatattg atattgaaaa tgcattaaaa tcattagacc
    33301 cttatcaagc tatgcaattt aaaactgaag aaggaaaaaa acacttatta aatgatttag
    33361 tgaatcaaga attattcttc ttagatgcta aagaagaaaa attagatgaa gaagaaatat
    33421 ttaaattaga aatgaaaaag atagaagaaa atgtattaaa gcaatttgct ataaataaag
    33481 ttttatctag tgttaatgta acagaagatg aaaaagtaaa attctttgaa gctaataaga
    33541 gctctttctc taaaccagaa agtgcaactg ctaaacatat attagtagat agtgatgaaa
    33601 aagctaaaga aatacttgct caaataaaat cagaagaaat atcttttgaa gatgcagctc
    33661 ttaaacattc ttcttgccca tctaaagata tgggtggtga tttaggaaca ttcggtagag
    33721 gacaaatggt tcctgaattt gaagaagctg tgttctctat ggctaaaggt gaagtaagtg
    33781 aaccagttaa aactcaattt ggataccata taataaaatt agaagacctt caagaaagta
    33841 cagagtctac atttgatgaa gttaaggctg aagttgaaaa aagtttatta tatcaaaaac
    33901 aaaatgaagt ttatggaaat aagataaatg ctcttaatgc taagtacgga aaccttgtaa
    33961 aatacaacga ttaatcataa ggtcatatat aaaaaagctg tcttttcaca atatttatta
    34021 gaaaagacag ctttttatat taaagtttaa atattcagtt tcatattatc attcttttat
    34081 tgtaaagaac tcagcttaaa agtttaaata agatttttaa ttatcattag ctaaattttt
    34141 atatccacgt attatctcat aacagtaacc tattacatct cttcttttta ttatcccaat
    34201 aaatgtgtct tggtcatcta taacaggaat gaaattttga tttaaagatt ttataactaa
    34261 atcttcaata tctgcgttga tggaaacagg agaattatcc atttttctat ttatatctgt
    34321 cactggaaca tcttccaatc cctttaagtc cagatttaaa tcatttttta atgtccataa
    34381 aaaatcacct tctgttatag ttccaacata tttaccatcc ttacttatta ttggaattgc
    34441 agagtatttg tgatattcca ttttttctag ggcttgcctt atagtgtagt cttcatatat
    34501 atatgctact tcactttttg gtgttagaaa gaataatatg ttcattacac tacccaccgt
    34561 tactgaaaac ttataaatat tactcaatat ttataatgtt acttttttgc agtaactttc
    34621 tcctttctta ttttctaagt attcttaata ctatacgctg taacaagcgt ttttcctttg
    34681 ctcattttaa tcttattatg ctttattaat atttttatat ggtctatcag tatcacttat
    34741 tctcttttta gaaaatttac taaaaattaa ttgacttaaa cttagccata ataattttac
    34801 tctacactat taattttaac atatttatct cattattaat gattttattt taataatttt
    34861 aatttatttt gctattaatt ttatttacaa aaactgaaaa aaccgctaaa tgattagcgg
    34921 cttatctctc atattactag aacactaata tatatgaatt tttaattata atctaactac
    34981 gttagcagct tgaggacctt tagctccatc tactacttcg aactcaacgc tttgtccttc
    35041 ttctaatgtt ttgtatccat ctccagttat agctgagaaa tgtacgaaaa catctccttc
    35101 accttctaca gatatgaatc caaatccttt ttcgttgtta aaccatttaa ctacaccagt
    35161 tttcattaat aaatcctcct aaaaaaacac aaatatttag ctactctttt ctgtaacctt
    35221 attactactc tatcatatat agctatgttt gtcaattatt attattttta tacattaata
    35281 atcaattttt ttactttata attttaaatg attattatct tttacacttt atttttcttt
    35341 ataatttttt aataatttat ttttattata tggaatctta tggacttatc actccaacct
    35401 aaatcccatg gcaccaacat tctatcagta ttatgacaag ttaccaaagg ataccctctt
    35461 gagtctaatc ctgtcactgt cgaaacatgt gttattctgc ctttcttctc ataaccaaca
    35521 aaatcccctg gacgtaaatt ataagcttct ttgtatactt cttcatagga acctttagca
    35581 attaatgaac ctcttccact atacagtgca taatttttaa aagcttgtgc atttacccat
    35641 gcttttgtac ctgctctctc gctataattc caaattgagt tctttttgaa ccttccactt
    35701 tcaaacatta tctgtgatgc aaagtttgca caatctccac cttctggatt ataatcccta
    35761 tagtttggat taaatttcat accatgttct tcatcagctg cggctccaca gtatttatgt
    35821 gcataatcta tagccttttt ttgttcatct gtaagctgta actctacacc atcttgttga
    35881 ccaatataat ttcttatatc atcagatttt atattttcta aatttaaaga gtctgcaaaa
    35941 gggtctgtat accactcttt agttatgaca tattgattat ctataatttt tacatttaga
    36001 taatgatatg tacctattct aaaggcattt tctttgtcct tttgattttc atatgaatac
    36061 ttatattcag tcgatactga acagattata ccatagaggt ctttttcttt ttcttttatt
    36121 tttttaatct taacccttgt ctttatgtct ttaaatttta caccttgctt actagaccaa
    36181 ttttctaaat acttcatctt ttttacttca ttttcataag cccacagacc aaatttttta
    36241 tccgtctcat aaagaccttt taaaatgttt tcatttttct ctaatattgc cttatttctg
    36301 taatcaaata agttttcaag caatagttta tattggtctt ttacatcatc accttcaaca
    36361 tttgcagatt ccatgacttt ttcttccata tttttcatac ttaaatcatt gattaaaaat
    36421 acacctgctg tagtagctaa agacaaaaat acaaatgcca ttataccttt gatgtactta
    36481 ttcttatttt tcagtatttt caaagctaca cctcccaaat agtacacctt acaaatcaaa
    36541 ttacaaagaa tattctgtca catatagtaa ttttcatatt taataattct ctattttatt
    36601 atgtccaata ttaaaaatta attgtatcaa tacactgttt tttttacaat tttttatttt
    36661 ataatctact tttttctttt ttttatagta atatatatgt atataaatat tttggtatca
    36721 ttataattaa tacatactaa tggagggttt tttatgcaaa aaaaagtcgc agcaattaat
    36781 gacttatctg gaataggaaa atgctcatta tcggttgcta tacctatact ttcagcatta
    36841 aaggttcaat gttgtccatt tccaacggcc atactttcaa gtcaaactgg ttatcctgaa
    36901 tttacttttt tagactttac cgatgaaatg gtaaaatatt caaatgtttg gaaaaattta
    36961 aaagtcaatt ttgatagtat atatagtggt tttttgggtt caaagcatca aattgagata
    37021 gtggctaatt ttataaacga ttatcccaat gcttttatcg tagttgaccc tgtgatgggt
    37081 gataatggag ttatgtatcc aatattcaca gaagaaatga gacatgaaat taaagaatta
    37141 gttaaacatt cagatttaac tactcctaat ttaacagaag cttgtttctt aactggaaat
    37201 gattatacca aaagcgatta taatagagat gagcttatat atattgcaaa atctgtatct
    37261 gatttgggac ctagcaaagt cgttattact ggtatattag aagatgataa tatattaaat
    37321 ttggcttacg atagagataa tgaccatgta ttctttacat cagtcaaata taataattgt
    37381 tcttatagtg gaactggaga tatattcaca tctatacttt gtggtatgtt agtaaataaa
    37441 catgatttgg gagtagcggt taatactgca acagatttta tatataaaac tataaattac
    37501 acatctcaat ttgatactga tagaaatgat ggagttatgt ttgaaaactt tttatcagat
    37561 ttaactaata tataaagtca aaaaaactat ccattttata aatacctata aatcataaaa
    37621 tttaggtatt tacaaaatgg atattattta ctaaactatt ggtatttcaa ttgttaccat
    37681 agcaccacca gttttcacag aattttcaat atataaaatc ccattatgtt tttgtacaat
    37741 attatttaca atatagagtc ccattccata atgagattta gaatttctac tcaaatctcc
    37801 tgtataaaac tgttctgtag cttttgacaa atctgcttta gaaaaaccac ttccacaatc
    37861 tgtaactaca aattttaagt atttattacg tactgataca cttatgtata gtttactctg
    37921 gcttggtgaa taatctatag catttgaaat tatattcata atagctctga ataacagttc
    37981 tctatctata gttatatttt taggcaaatt atcttgttta taaaactcca catctaagtt
    38041 tttagtacta gctaatgctt ctatttgcac taagacatct tttataaact cactcatact
    38101 gattgcttct ttatttaata tatagccatt ctctgttttt gatatatcta ttaaagtatt
    38161 aatatatttt tctatttgag tgacaccctt tgagatatat tccatgtatt ctaataactc
    38221 aggattttca tttatttcaa ttaataagtc agtatttcca tgtataattg ttagtggtgt
    38281 ttttatatca tgtgccagtg cagatatctg ttcctttcta ttttcttcta gcatccattg
    38341 tttttctaaa gaatctttta acgccaactt cattttatcc atagaaaaaa ggacattatt
    38401 aatttcataa attttactag attctacaac aaaatctaaa tcctgttgtt ctattttttc
    38461 tgtagtattt tttaaaagct ccatttcaat attaaatttc ttgccaaata cttttgataa
    38521 tataacaatt tcaataaaaa atattatact aaaaataatc atacccaatg tctctggttt
    38581 tggtaaatat gctcttaaaa ttggagaact atactctgat actattttgt attttattat
    38641 aaaaacttca tctttcttaa aaaactttat ataactttct gaatatgcat gcctttcttc
    38701 aatatctctc attaaattcc atacttcttt tgattctttt ttattaaagg tccctgaaat
    38761 taaactccca tccaaagtat aaaccccata ctcatatata cttggaatta tatcttcagt
    38821 tactttttca cttgaaataa tctgttcttt atatttatta aattgttttt ctgcataatt
    38881 agctggtaaa attacacctg atgataataa tacagaaaat gataacatta aaaggagtac
    38941 aattgaaatt gtcataataa agaataaaga taaatatttt ataaaaatag ttcttaactt
    39001 ttcaactttt ttgttgttag attttttacc tccaagcatt tgtaccctgt cctccaatag
    39061 tttaattaat tcataattaa tatctaacca gttttttatt tgattatttt atatcttttt
    39121 attgctaagt tatattttaa cataataata taaataaaca gtcaattttt actctattct
    39181 tctgattttt taccttccca tttagaaaac caaatacata aaattacaaa tgctaaaatt
    39241 gttacaaaac cacacattaa acctgttgat tgatatgctt ttattgattc aacctttata
    39301 tattcaaccg ttttagaact cgaaaaagac gaccaaatag ttataaatct aacaccccat
    39361 gcacaaggaa aatactgcca aataccagaa cccaatccag ttaataataa tgctgaaagt
    39421 aacatttcaa ctatacctac tccaattgat gttccttttc cgaaccttaa acttaagaat
    39481 aaatgtaata tgtattcaaa taaattacac ccaattaaaa ttagaattga aatcatataa
    39541 aagcttgatg caaagtaagc cttagatata ccaaatttaa aacctaatac agacactaat
    39601 gttgctacaa aaccaagaca tactaagatt atatatttac ttataagagt aagatatttt
    39661 ggattagatg ttgttaacat atgtttataa ttccctgcat aatattcttg ttcaacaaac
    39721 attgaacaca caacacctga caataaagga aaagctattg ctataacttg taaatatgct
    39781 actatcttta gtatattatc agctcctgaa accttataat accataaaaa caatcccatc
    39841 cccattaaag caatgcaaat gtgcattagt attataaaat ttctctttaa ttttattaaa
    39901 tcagaacaaa atattcttat taactgtctc atattacttc acctctctat tattgaacca
    39961 aacccttgta gctaaagcaa ataatacaaa taaaacaata gatattaata ctcctggcaa
    40021 aataacagca ttatttaaaa attcacttcc ctctggtaca ggaagaccat ttggcagaat
    40081 atgcaataca acagccatta atcttgaagg aatcgaatat ggaaacatat accacatttc
    40141 tgtagttgag aaaacagcaa ctccaacaat agtaaagaac atatttatta gaactgtaac
    40201 aaatatacca aattttgaag ctaaaaacat acaaagagga atctgccaca taaatagtaa
    40261 aataattaat atagttgcaa tgatattttg acctattgaa atagtttctt tatagattat
    40321 cccaacaaaa actacaccta ttgcagaaat aattgatgct ataaaacaac aaataataca
    40381 gtaaatcatt tttccagtcc aaacgtcttt catttcaatt ggcaatggta aaataccacg
    40441 atatttactt ttttcatctt ttaatactat taaagaagat attaatgtta atgctcctgg
    40501 aagaaatgtc gtataccacc agttgaaagc agcattttgc cctccaccta gtccacataa
    40561 aagtatacaa aacactggaa ctatccatat caacttcatt ccaaaagttc ctttcatctt
    40621 ttgaaattcc actctaataa atctttccat attactgccc tctctttcta ttttcagcta
    40681 caactttcat aaaaagtttt tctaagtttt gttcttttga tacttctcct tgataaccca
    40741 ttactccatt agaaattatt cctatttcat ctacaacttg ttcaacttca gacaagatat
    40801 ggcttgataa aataactgta attccttgtt ttggaaaaga acgaatcaat tctctaagtt
    40861 cttcaatacc aatagggtca agaccatttg taggctcatc taagattaaa agttttgggt
    40921 gatttaataa tgcaatagca ataccaaggc gttgcttcat gcctagagag aattgacctg
    40981 aacgcttttt aaaggtatct cttaaatcta cagtctctaa aacttcttca atgcgagagt
    41041 caggaagacc aagtaaagta gtatggactt ttaaattttc tcgtgctgtt aaattctcat
    41101 atatagcagg agactcaata agagaaccaa tatttgataa atcctttcta gtccatctat
    41161 gtccctcaaa cattattttt cctgaagttg gatttaaaat cccagttatc atttttaata
    41221 aagtagattt cccagctcca tttggtccta ataatccata tatagaatta gatttaattg
    41281 ctagtgaaat gttatcaact gccatctgct ccttaaattt tttagaaact ccttttacct
    41341 gcaaaatata attactcata attttcatcc tttcttttgt caaacttatt tacaagaatc
    41401 attctaaatc ataaatataa ggattttata agaattaaaa aacaaaaaaa gatgtgttaa
    41461 aaacacatct ttttttatct taattctatt aattttccat tgtagtatat ctctacttct
    41521 tcaatccaaa tgctattatc ttcttcttgg atgacatttt taataatatt atttatagta
    41581 tatattatat tttgttcatt caaataatca tctttccaag aaactctact ttttttatct
    41641 ggttctatca agtttatttt aacaagatta tctttttcct taacttctac ttccatgtct
    41701 aaaccattaa aatactcatt tgataatgta tctaagatta atcgcagttt atccttaagt
    41761 gaactttctt catcaatctg taagtacttt actattttct catcctttga aattatctct
    41821 ataggtattt tagtagtttt tttagaatta atcattttac tagttgtttc ttcttttgca
    41881 tcttcatcct tctttacaac tgctgattct ttagaatcaa ctagctcaac tgcactgatg
    41941 ctataatcca tacatgccgt actcaataaa gtagtagcaa ttattaaaaa acttactgct
    42001 attttattca taagtatccc tctcctaatt ctctttcgat acttattata ccatagtata
    42061 gattatattt ttatactttt aaatcaattt ataaattatt atagtaaatt atttacaatt
    42121 ctaagctatt tgaatttatt tttatagtat attctttctc taaattcgac agatttttat
    42181 tcaaaagccc ttttatttct ctcgtatttc tatacttgtt gctatgttct tcactatgtt
    42241 cataatcata tgaatcattg tcatattctt catcattatt aaattcttca attgcttctt
    42301 ttgactttat atcacaatta aatttatact tatttactgg tatatcaagt cttaccttag
    42361 aatttggaac ttctatgtcc aggaacttag caattggcat atcagagtac aagtaaaatt
    42421 cactttcata atttgaattt ctacctattt tctcttttat atttacattt tcaggtatat
    42481 actcttctat attattgata aatacatctt cattctctga agatatatac aatgactctg
    42541 attctatgtt tacattttta acgcctaaaa ttgattttgt tgacaagtga agattgttat
    42601 tagatattaa gtttaggttt tctaatctat ttactttgtt ctctgttata gctctactaa
    42661 aacctccata agaagtttta tatgttatag tatttgaagc tacattatcg tatacaaata
    42721 agtgtgagct tatacttgat gcatttatgt ctacattatt tggtacatat attataattt
    42781 ctctataatc atgtgaaaac atactattta tagatgtatt taataattgg tcgaaatttt
    42841 taatcttttt aattttattt tcatattttc tttcaccttt tacaactaaa gtcttatctt
    42901 ttaaagttac attgtatttg taaaactcat tatttcctct tgttgttaca cgcacatctt
    42961 cacttgaact tttctttatt gtaacgttta tattgtcaac agctatatct aacttgtcaa
    43021 tatttacttt ttcttgataa agtttatttt cttttttaaa ttcagcttcc ttttctaaac
    43081 caaagtttat taggcttggc ataactaaaa tccctgacca tgttgtccct attataccta
    43141 ttaccaataa aaccgcagca aatatagcaa gttttttatt catgtttatc ttctcctttc
    43201 ttattttcta tatcttcaag gtccttatat atcgcctcaa aatttatact atcatcatta
    43261 tattcatcag tttcttttat gctttcttct tctctattgt agtaatcatt attatatgaa
    43321 tcttcattaa tgtctttatt caaatcttca tcatttaaag tagctttttt tcttttttcc
    43381 atcttttcat ttgcttttat ataaatattt tttctcttta tccaatgtat ataattattt
    43441 agtaattgtt tacctagttt tatggcaaat aataaaattt gccatgcaag tatctcaagc
    43501 cctacaaatg ctatggttgc gaaaatacaa aacatcataa catctggaac cattgctata
    43561 aatttaatca caaatggaat taatataaca aaagcaatta atgagcatac taatgcaata
    43621 gtagcagata caatagcaca tacaaacgca aatgctggaa caattagaaa taaagataac
    43681 actactaata acccctttat aacttgtctg gataatcctc ctacaccttc ttctatactt
    43741 ggtgtaagtt tatcatttat attttctttt gatttattgt acttttcctt agcttcatct
    43801 ttcaagatag aataatcctt ttttacattt gatttaaatc tactaaattt accatttaat
    43861 atgtctgtat tcattatttt tccatctata ttttcttttg atttactata cttttctttt
    43921 gcttcatctt ttaagataga gtaacctttt ttcatatctg atttaaattt actaaactta
    43981 tcattcaaaa catctgtatt tattattttt tcctcttcaa tatttttttc tttagtttgt
    44041 aagataagtt cttttgctat agattttggt gagccaagtg atgctattat ctccatatca
    44101 ctctttccct ctataagacc atctacaaaa tactcttcat aatctctcaa tatatcatta
    44161 acttcgctct cagaaaaatc tttttttaga taatccttta aaatttcaag aaactcagtt
    44221 ttattcaagt tcattacctc cctcatcttc acttattaaa atctcaacag cctttacaaa
    44281 ttctctccac tcttccatca gattggataa attctctttt cctagtgaag ttattctata
    44341 gtattttcta gcaggacctt cattagattc tagtatatat gtttcgaaat acaaatcttt
    44401 tgtaagtctt cttagaatag gatatattgt tccttcattt acatctatta ctttagagat
    44461 gttatgtact atctcatatc catacatatc tttcttagat atgagagcaa gtacacaaat
    44521 ttctaaaaca ccctttctaa attgtgtgtt catatactcc atcctttctt taaatacaca
    44581 gtattgtgtt ttacaaggta ctatgttaaa acttcttata tcctcataat aacacagtac
    44641 tatgttctgc acaatagtta tttttaaata ttcttgttga ttaaatcctt ctataaatgt
    44701 ataatactct aatcagatat attttatgaa agtggtgata aattggctaa aatgaaagat
    44761 gataaaacaa tattaatcct aactgctcaa tttggtgctg gacatataag tgctgcaaaa
    44821 gcagtcaaag aatgtattat tgaaaaatat agtaactata atgttgttat acaaaacttt
    44881 ataaatgcaa gtattcccat gatgaataag cctatggtaa aactttatga aaacaataca
    44941 aaatatactc ctggattata taattactat tattacttta agaaatcgtt tgattcaaga
    45001 catgatttat ctcataaatt atatacacct aaactttctg agtatattgc tgatataaat
    45061 ccagatttga ttatctctac atttccacta gctgctgctt gtgtaaataa ctttaagata
    45121 aaaaatcctg atataaatat acctacactt acagttataa cagatgttgt agatagtatg
    45181 gaatgggttt ttgaaaatac agatttgtat tttgttcctt ctcctgaaat aaaaaataga
    45241 ttttttcaga aaggaataaa tcctgactcc ataaaggtta ctggagttcc tgttgataag
    45301 agatttcaaa ttgaaagtaa agaactatgt tgtgataaat atagactatt acttctaggt
    45361 ggaggaagag gtctatttga tatagatgag gattttatgc attggataga tgaatttatt
    45421 gaagaacata gtaattctat agaaattaca atagttactg gtaaaaacaa aaaattatat
    45481 gacaatctaa ctcataaaaa acctctaaaa aatattaaag tacttggatt tgtaaacgac
    45541 atgtataatc taataagaga atgtgaccta atgctaacta agcctggagg agcaactata
    45601 tttgaagcta ttcaatcaca aactccagta ctcgtaaaaa tgccaaaagt tggacaagaa
    45661 attgaaaacg ctaaatttat aatagataag ggtcttggca tgatttatag tgatgaccta
    45721 gaccttaaaa acatatttta taaattagta tcaaatgaat ttgattctat aataaacttt
    45781 atgaaaaaaa atttaaaaga atttaaaaca gtcattcatc cagagaaaat tgctgattat
    45841 atatcagaat taatagataa tcattacagt taaattgtac tattaaaaaa tttcaaacat
    45901 aaaattaaag gcaatcaagt atgattttac acttgagaat ttactcatag tgtttaataa
    45961 tacttgattg cctttatcat atcaaaatca aattgttata ttagtatata tttttcttgt
    46021 actgcatata cagttgttgt atttcttcca tacttctctt taattctatt tgtaaatctg
    46081 aagcagtctg gtaatcctta ttttctatag cttctctcac tctagtgaat agtgattctc
    46141 tagttaaagt atccttcata atattgaact ttaaatccga tattgagttc caaactacct
    46201 catcaagcgc atccatattt tcttttgtgt gtatcttgac aatacttctt attttttgaa
    46261 tcccagcctc tattattcta gtttttaatt tcttttgcca cttatctata gctccaatct
    46321 taaatgattc tattatacta tcagtaaata catcaccttg ttttaaagat tttaattttg
    46381 aagcatatat ttctaagttt ttcatatttt cataaactgt agctggtggt attccaaatc
    46441 ttgcatttct ttcttccaaa ctataatgtt caaatacatc attttcatct ctatatgctc
    46501 tatctttttc taaatagaaa ctttcttcac ctacattttt agataactct ttttcaagtt
    46561 cttttgtact aagaccactc ttagctgctg cttttatacc atccaacatt gtttgataac
    46621 atcctgctat tactaaatac gtgttagata gagggcttgg tgaccttaat tcaaatctta
    46681 cagtctttgg atttttcata tctcttatta atccaacaag cactgaccta tttcttgatg
    46741 gaatctcata actatgccct aaagatgtaa ctatacatac aggagcttca aatccaggaa
    46801 ctaatctatt aaatccatca ttagaagctg ttacaattgg gtttaatact tcataattgt
    46861 aaagaagtcc cataagagcc ccatatccta gttcacttag ataatcttct tttaaatctt
    46921 ttggagcaaa tagatttttt atacttccat cctttaactt cgcacttact cctacatgtg
    46981 tatgtccacc acttcctgct actccatgaa ttggttttgc tttaaatgta acttctagtc
    47041 catgtgatgt aaatacatcc tctataacat ctcttactaa taattcattg tctgctgctt
    47101 gtaatggtgt agaaaacttc caagaaacct ctaattgctc catagcatgg tttgttcttc
    47161 catctatact aatagaactt tgtattcctc cgacctcttt gtgagccatt tcagggttta
    47221 cacctagctt ttgaagtata attaaacttt tctctaaaca agttcttata ataccatgag
    47281 ttcttttcca gtattgctct tttaggcttt gtgatacata taatttctct aagtcagctt
    47341 tatcctcagg agtattaacc cagaactcaa gttctgtagc tgctgttaac attatttcct
    47401 ctatatcatc tactgaatct attcctatgt tatttattac atgtggatat tctctaaata
    47461 tttcatacat tgacttttta aagtacttat ctgctttttg aagtactcct ctagaacata
    47521 cttttttatt atcatgtatt aaaaatgcag gtatctttaa tgttccaaca ggtagaccta
    47581 cttcttcgtc tatatattcc atattgtaat ctacatacca atgacaactt ttatctggca
    47641 ttaaatctac tttcgcatta tttaatgtag ctatattata aagctcaaca cttgaaccat
    47701 cagtctgtat agctgattcc aaaaatttat ctatatcctc caaaaataat tctacaggaa
    47761 tcttttcatc tgttgcattt cctcctaaat caacccccat taaggaaaca aatcttatat
    47821 ttttattgct ttttaggatt tctcttaatt cttcattagt gtgtttatct ttctctatta
    47881 cgtataatag actatccatt tttccactct cccataattt ttatgtatat tttattttgt
    47941 taaatacaag ataaatttca ttttccttac atttatgaat ttttcttgca aattattcgt
    48001 gttttattcg tgtttttatt tatattatta tatatcaagt ataaaaagtt cgcaatattt
    48061 tttattggaa aaaatattat acatacaata gtttaacatt tttacaaata tggggtatac
    48121 taaaataaaa gtatttttat ttgaaaattt aattttattt ataatataat ctatagtaaa
    48181 agaaataata aaaaaattta ggagataaac tttatggaat acataatttt cgatttggaa
    48241 tttaaccaag gatttgataa aaaactcaat aaaactgtat ccaatgaaaa gtgtcctttt
    48301 gaaattatac aaataggagc aattaaattg gattctaaat tcaatataat agatacgttt
    48361 aatagttatg taaaacctac aatttataaa gacatacatc cctttattag tcgtatgact
    48421 aatattaaaa attctgattt taatgattcg cctactttcc ctgaggtcta caacaatttt
    48481 ataaaattta tatcatcaca agaccctata ttatgtgttt ggggagctgg agatttaaag
    48541 gaattataca ggaatatcaa ctatcacaag ctaccatcaa attccttacc taaatcttat
    48601 attaatatac aacaacatgc atctaaatat ttcaataatc cagcaggaaa aagcattggc
    48661 ctacaaaatg ctatttctat attagaactt gatgaaaaaa tgtcttatca caatgcttta
    48721 aatgatgcat attatactgc taaagttttt attaagatat acaatccaag tatagtccca
    48781 gatatatatc tttatacaag tataaaacct aaaactataa gatattctaa caaaaaaaga
    48841 gttgattatg ataagttatt tgatgaattt aggaaaattt taaatcgtga attaactaaa
    48901 gacgagaaaa aaatcattaa cttagcttat aatatgggga aaacaaatca atttacatta
    48961 gaaaatgtta agcaaagaaa aaacaaatag agtttattta gataaaaaat aggcatgtag
    49021 attaaaaaac tagttaactt taaatttata tctacagccc aatttttatc ataattaatt
    49081 tttattttat ctctaattca actggacaat ggtctgaacc taatatttca gtgtgtatat
    49141 ccgcacttac taatctatct tctaattttt tggatgcaca aaaataatct attctccacc
    49201 ctgcattatt ttttcttgca ttaaatctat atgaccacca actataaaca ccttctttat
    49261 caggattaaa atatctatat gtgtctataa acccactgtc taataattta gaaaacttct
    49321 ctctttcttc tttagtaaaa cctgcatttt tcatattatt tttaggattt tttaaatcta
    49381 tttctttatg tgcaacgttc atatctccac acacaattac aggcttatga ttatctagtt
    49441 tggttaaata atctataaag tcgtcttccc atctagttct atattctagt ctctttaatt
    49501 cagattgaga atttggcgta tatactgtaa caaagtaaaa atcttcaaac tctagagtta
    49561 tcactctacc ctctttgtca tgttcttcta tatttattcc atacattact tttaaaggct
    49621 ctttttttgt aaatatagca gtacctgaat aaccctttct ctcagcataa ttccaatatt
    49681 gaaaatatcc tggtaaatct aactctattt gcccttcttg caatttagtt tcttgtaaac
    49741 aaaatatatc tgcatctact tctttgaaaa agtctaaaaa tcctttccca acacaagctc
    49801 ttattccatt aacattccat gatataaatt tcatacttat actcctcatc taaacattga
    49861 cacactcccc atagctaaag atgggggctt ttcaacaatt ttattgtaaa ttcttaattc
    49921 acttttattt taacaatgct atactataat ttcatctaaa attactattt acttaatacc
    49981 taaaaatata tgttttaatc aatttttaac ttttttgtta aatcttcagg gctcattgaa
    50041 gaaacataca tatttgttcc aagttcaaat cctccaaaat tatattttct tgggattatg
    50101 tgcatatgaa cattaaaata cgattttgtt tcaatctttg ttggatgagt gtgaatacat
    50161 aaattaaatg gcatatatcc attgatatta tataacttct taaacaactt ttcaaatatt
    50221 gtagaaagct cctgtatatt attatcattt aactcaccaa actctatttt atctttaaat
    50281 attattctta cttctccact atacttggtt gcatatggta taagtaccaa aaaagcttct
    50341 ccattataaa caactcttct atctaaactt atttcatttt ctattaaatc atcatacaaa
    50401 gagcttttat tgctgtcata atactccttt gaaaccaaca gttcattcgt aatttcaggt
    50461 ggaataaaag acatagacaa tatttgagca tgtggatgca tcaaagatgc tcctgccttt
    50521 ctcaagaagt ttttgaagat actaacatac tctactttat catctttcga caaatctcta
    50581 aatctatttc tatacataaa aaaaacatct tcaaattctt tttgactcat gttataaaaa
    50641 ctacgattat gtttatcgct ctctatcatt acttcatgaa caccatatac atctcttgcc
    50701 atatcatcaa ttataggaaa tttattgtag acagatttta caagccatcc ttcttcactt
    50761 tctatttcaa ataatgcatc agttgcatga gcttcatttc ctttgcaaaa tgggcattct
    50821 tcatcatatt cattagtttc ttcatcttca tttgggatat ctgctgtatc taaaggtctt
    50881 tttaacctat ctgtagcaaa tataacaaca tcattggtaa ttggatctat tcttaattct
    50941 ttcataatta acacctctta gttaatagcc tttaatataa ttatatgata tttatcgtat
    51001 ctgttaaata aatttataat attttttata attttgcata tttattatta tatattttgt
    51061 c
//
LOCUS       DAJMZY010000019        49619 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.019, whole genome shotgun sequence.
ACCESSION   DAJMZY010000019 DAJMZY010000000
VERSION     DAJMZY010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 49619)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49619)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49619
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.019"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            248..361
                     /locus_tag="OE968_001058"
     CDS             248..361
                     /locus_tag="OE968_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013483530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCP7218351.1"
                     /translation="MIMGRHLWNPSYFVATVLENTEEQIGKYINNQKKQVK"
     gene            363..1481
                     /locus_tag="OE968_001059"
     CDS             363..1481
                     /locus_tag="OE968_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCP7218352.1"
                     /translation="MIVVEKAYKFRMYPNKKQQELINKTFGCCRFVYNKYLAKRIEVY
                     KNDKETFTYKQCSSDLTNLKKELKWLKEPDKFSLQNVLKDLDNAYKKFFKEKAGFPKF
                     KSKKINRFSYKTNFTNGNIMYCGQHIKLPKLGMVKIRDKQVPQGRILNAAISKEPSGR
                     YYVSLCCTDVDIEAFENTNNQIGLDLGIKEFCISSCGEFIENPKYLKKSLNKLAKLQR
                     ELSRKTIGSLNRNKARLKVARLQEHIANQRNDFLQKLSTKLIKENDIICIEDLQVKNM
                     IRNSKLSRLISDVSWSEFIRQLEYKANWYGRQIVKVGKFFASSQICNKCGYKNEEVKD
                     LNIREWICPSCNETHDRDINASINILKEGLRLITIQNK"
     gene            1632..2849
                     /locus_tag="OE968_001060"
     CDS             1632..2849
                     /locus_tag="OE968_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HCP7218353.1"
                     /translation="MLIGLIAAFGLVLQKKKASDVIKGSLLAAFGIIIMETGTGMLVS
                     SIAPINGAFQSISGGAVTKGLSDVTFTASYGGIIGLAMFAGLAIHLMIARFTPIKTIF
                     LTGHMLYWFPFIFVASGVEAGLNGGVLITFAAVLSALYWSIMPWLLRKYVFDVIGDDS
                     FTLGHPSGCLALISGFVAKLVGNKEKSTEDINIPQSLSFFREISISGGMAVFLMFIVV
                     GIVIPGAFKDSNEFIGTYAIKQGLSFGAGLIIMLHGVRMLINQIMPAFQGISEKVVPN
                     ALPAFDCPILFNYKPNAVLIGFLVAMLTSTAMILIYNYFNVFNLLLIPLVITSFFECG
                     AAAVIGESQGGIRGAIIGTAIAAIFMVVLVGISAVIYSGTIQNWILIFGGNDLSLFGI
                     ISRFIGSLFGGIL"
     gene            2852..3592
                     /locus_tag="OE968_001061"
     CDS             2852..3592
                     /locus_tag="OE968_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HCP7218354.1"
                     /translation="MKFKYIDEIRRLIDIIENEEKVNMEKAVQIFVEAIESKNAIFSF
                     GASHAGILTEELFYRAGGCVLINPVFAKSLMLDTAPITHTSKMERLEGYGTALADKTP
                     IKKGDVVIVHSVSGRNPVSIEFAMKAKENKAIVICITNLSYSKSVSSRHSSGKKLYEV
                     CDLVIDNHGQKGDACVEIDGLNQKVSPTSTVIATTVMNSIIAQATQELVNKGLKNPPI
                     FYSANIDGGDELNKKIFDEYKSVIHYEY"
     gene            3915..5225
                     /locus_tag="OE968_001062"
     CDS             3915..5225
                     /locus_tag="OE968_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HCP7218355.1"
                     /translation="MKKENKMEGIKVGMLKKLCSLAMVAIMTTTLITGCSSGNGKDSK
                     KDGEKEKLVLWMPPVENNMKEVWDPILDKFEEKNNCEVDLQIIPWDNYSEKFATAISA
                     GEGPDVGYMYAEMYPQFIESGAVEDLTNYATKEDKEQSIYIKTSEMMGGMYGMPFQAA
                     NPGVLYYNKDILEKLGEKPPKTWEDFKRICKKATQDTDGDGKIDQWGLAQGWGAKTFG
                     NLNWNWYPYLWQAGGDIFNDDLKSVKFNDKSGLEAANFLKELQAYVPEDSLSKDSNEM
                     IESVFGPGKAAFTIMLSSAATSVFDESFPDLNWGFVTGLEDKKAATFGAVDHLSLMSS
                     AKNKELAYKLIQHMLSVESMTEFHKAIPRAPITKGEPYQGDERFKEMVENDKNVYRPL
                     VVGPHGVEIYEYLWKELQTMISGDKTPKQALDDAAKYSNDLLAQ"
     gene            5323..6240
                     /locus_tag="OE968_001063"
     CDS             5323..6240
                     /locus_tag="OE968_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCP7218356.1"
                     /translation="MENLVREFEENSKRKKTKLNIKPYMYILPLGIILVAFYVIPIIM
                     SIYFSFTKYNIISPATFIGLENYKKLFTDETLKVSIINTIKFTVVVVPCQTILSLILA
                     VWITGKGNSKIASFAKGAIFIPVLSSMVLIGMVWRALLNGEGSIIYQVLGAFGIESSK
                     LLGDSKTALPTLMFISMWKNIGYFMVIYISAIMNLPKHCYEVAKVDGATKLQEFIKIT
                     VPLLKPTTIMVVFLGSIWSLQVFDLIYTVTGGGPGISTMSIVMHAFNLNFKNFNSGYA
                     MTVANVLFLLIAVVSILQNKLVRRDNSDF"
     gene            6256..7065
                     /locus_tag="OE968_001064"
     CDS             6256..7065
                     /locus_tag="OE968_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HCP7218357.1"
                     /translation="MKTARRLLSDGLLLFIACASLVPFIYMLIISLKITYNSYSLDIS
                     FSTVTLQNYIDIFTKKGFAQYFFNTAIVSFSGVLLNLVFSTLAGYSFAKMDFKGSDKL
                     FLFMIMTLIIPSQVTMIPLYIIMKHLGWINSYLALIMPIPTAFGVFIMRQAILGVPKE
                     LLESAKIDGCSDFRILIQIVLPLIKPALITLAIFTFMGAWNEFMWPLIATTKDTMRTL
                     TVGLSTLKTFQITNYGQMMAGATITFLPPFIFYLILQSKFVEGVSLSGIKG"
     gene            7123..8871
                     /locus_tag="OE968_001065"
     CDS             7123..8871
                     /locus_tag="OE968_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4091 domain-containing protein"
                     /protein_id="HCP7218358.1"
                     /translation="MEISYVLKDCTFKHNKYSVVEAETWKDKDLDIVVAKGEKFAFQI
                     MLKATEEFNCTIDKSSAISWKGLGNRVRLALNMPNSLENNFSINILGYVQDDTKAFVN
                     DAILRDKDVLVEQYLPQTFWIEGQVPEDFEENNLDIGIDIFKSFGYEDEEKVCTIDVP
                     VKVRNVVLKPLDESKFFLDLWQHPSCLARMYKVELWSDIHFEIVDNYLKELASLGEKV
                     ATVIVSDYPWAGQSCYKVYKNPSNLYEYNMVSVSKGLDGKIKCNFESMDRYISIADKY
                     KMAKEIDLFGLLGNWCAGEFGNPVEGYKDPIRVRYFDEKDKVFKFINNTNDLKEYIGL
                     VLNHLIECGLWDRVRIIADEPNNPEVVKECIEFINSTVSTHQVKYKSATHDQNFLDRA
                     KDEIDDMSINLKLTIQNYKDIESLKKKINDKGGILTWFVCCFPEKPNSFLSSPFVENR
                     IIGWYTYYFGLDGFLRWDYNLWTEDPWKDSSYKFPIWKAGDMFFVYPGKDLKPVRSVR
                     MENLRFGIQDFELFTMLEKEKGREYIEVELMQELLNKKENAEIKGFGDIELGYSLDNW
                     GYDKVKKYVLELLDRV"
     gene            9133..10155
                     /locus_tag="OE968_001066"
     CDS             9133..10155
                     /locus_tag="OE968_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 5 protein"
                     /protein_id="HCP7218359.1"
                     /translation="MFGGINIKRIGIIIMFFLSISFIGFYLVIRDNSDTVKMQRGINI
                     GNALESPKDFPWDVKMSNKFFDDIKDAGFDTVRIPVRFSDYTSDSDNFKIDEEFFKKI
                     DKYVDYALDKDLIVVLDLHHFEEIMKEPRVHKEKFLKIWQQIANRYQKYDKKLVFELL
                     NEPKENLYSQLLNEYIEEAIKIIRKTNPKRTIIVGPYNFYQIDYLNELNIPKDSNIVV
                     SFHYYEPNDFAFQGNIYHKGFEHLSNITWEGTNEQMDYLKKRFDTVENWANKNKVKIF
                     LGEFGITKEAPEASRRAWIKAVREEAEKRNFSWAYWELASGFGIYNQIEGTWDRDILS
                     ALIEKR"
     gene            10160..12466
                     /locus_tag="OE968_001067"
     CDS             10160..12466
                     /locus_tag="OE968_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HCP7218360.1"
                     /translation="MKKNSKKILITLTIITNVIYILWRIFYTVPKEEGKFALICAIIL
                     LFVEIMGMMEMFVHYYGMSNIEYPEKPIISEELYPHVDVFIATYNESVDLVRKTVNGC
                     IHMQYPDKKKVHIYICDDGNREEMCILAEKMGVNYITRTEREGAKAGNLNNAMQHTNS
                     PLIATFDADMIPMHDFLIATVPYFLKNEQAKKDGEKEEYEKVGFVQTPQSFYNPDLFQ
                     FNLHSEGRIPNEQDYFYRDIQLARNRTNSVIYGGSNTVISREALEEVDGFYTYSITED
                     FATGILIQSKGYRCYAIPEVHASGLSPTDLKSLIKQRERWARGCIQTGRRLNILFRRG
                     LGFWQKISYISSITYWYASIKRFVYIMAPILFSVFNVIVVKCTLLQVLVFWLPMYILS
                     SLSLKIFSQNIRNTRWTNIYETIMFQSLMPAVILETFAISKNKFSVTNKSKLEENRMY
                     KFLQGIPYFIYMVLSIIGILKMFVAIFKMSSMTYSVVLFWLIGNLFNLVMATLFISGR
                     QQLRKSERYIAEIDFKLKQNSYVLSSKTIDISENGFAFLLENPEYISPEEEFEVEFRE
                     KSGNEMYIANMKAKIVNVVEVNSKWKYAAYITHIEDSEIDNWMCIVHDRIPTLPMTIS
                     NQLGFFDDLQINVKKRIEKTRTLSRRSPRINMNFQMDIKNTGKLRIVNFNYQYVLLNF
                     ENKSIYPKEIALEINENIVLECDLCEGKIDERGILYKVNNIDSIMQNFFLRDEMMDWI
                     LQNKKILDSKPSEKKEKSIDEFEPMEYI"
     gene            12438..13553
                     /locus_tag="OE968_001068"
     CDS             12438..13553
                     /locus_tag="OE968_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218361.1"
                     /translation="MSLNPWNIFRRDEMKTLKVFFCSTKYLILVFIFFINTTFISSAT
                     SDKILDLSFKKIETDLSSKITYEDTGVKIETDSSKSDKERYLYIYQNIKENWSMYNNF
                     YIEIQNKNKSSQRINLSIQSKNMLEFRLKEGSEVFLEGKNIIYSDKIKEGCIEVPGEF
                     EGKIYVNFNSLINEESNVVLDSNMLSNIVSWGITFIPSDEEHNIVIIKKISLLSEEKL
                     RFLNNIKIIGDEEVQIPVLGQSISQYEVLGLKSDSKIKYSLMGKQDNVSISQNGKLTL
                     SNKAKPGQIILQVNVDDKFKIGKKITLTESWSINKKDKDGVPYTLVSPEQSPTVQDMK
                     KINFMNNIITFVRILFVSLVIICFGIYLYWKKCSKTK"
     gene            13571..14989
                     /locus_tag="OE968_001069"
     CDS             13571..14989
                     /locus_tag="OE968_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBOAT family protein"
                     /protein_id="HCP7218362.1"
                     /translation="MLFSSLIFLFYFLPITLVLYYVFRFNRTIQNMILLAVSLFFYAW
                     GEPKFVVIMIVSIIMNYIFGLLVDRYRESKIKVKVFLVLMCAYNIGVLFIFKYLAFAL
                     RNISELISTELTIPNIILPIGISFFTFQGMSYVIDVYRRHGEVQKNPFYVGLYIAFFP
                     QLIAGPIVRYESVAEQILNRKETWNKFSIGTCRFITGLGKKVLISNNMAIVADYIYTM
                     NSQGEIAASLAWLGSIAYTLQIFFDFSAYSDMAIGLGLMFGFKFEENFNYPYISKSIS
                     EFWRRWHISLGMWFKSYIYFPLGGSRVANKDIMIRNMFIVWLFTGIWHGAEWTFVIWG
                     ILNFVFLIIERFIMFEKIENHNFIKHIYALLVVNFGWVLFRSPNLKEAYNYFKAMFGG
                     NGAIWSDYTYMFLKEYWVFFIFAFIFSVPIAKKINKFVVEQAKYSMIFNVFYPISAIL
                     LFFISVTYLVTGSYNPFIYFNF"
     gene            15004..16212
                     /locus_tag="OE968_001070"
     CDS             15004..16212
                     /locus_tag="OE968_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218363.1"
                     /translation="MNRFFKVRLITAIMFLIILFAFSIFNVCYSGKDTIQEIKNSIAE
                     KSSLKDTISSIDNTVNDKVIYKNTFIETYGYLQKLMGKNEFSKFSVVKDTSGKMHYTY
                     FAKAPNPVGVIADRVRKFSDEMEKQNTKLVYLMTPDKYIKGVTKFPKGIPYSYSNETA
                     DNFLNQLKKYNVDYIDFRENILKSGIPKDDLFFKTDHHWKVETSFWAFGELVEQLNKK
                     YNMNLDENHYYRDKDNYNSIVYPKSFLGSMGRKTGILYGGIDDFTLIYPKFKTNYTYY
                     TDSKSQKFELKGRFEESLILSYPFNADLDLMDGQSDKYFTYLLGNRPLVKIKNIENPD
                     GLKVLFVKDSLIVPTAAFFSSVCSSIDMIDPRYYDGDILEYAKSHDYDFVFISVYPQN
                     LTKEFFPFCE"
     gene            complement(16286..17674)
                     /locus_tag="OE968_001071"
     CDS             complement(16286..17674)
                     /locus_tag="OE968_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:dicarboxylase symporter family
                     transporter"
                     /protein_id="HCP7218364.1"
                     /translation="MESSFLSQFLMITDFKTIFFIILLLGTFFIVRQFEKKKIKFSLR
                     TIYATVLGLILGIIIQAFAGFPNDTTQVTWLQEVSKWYSLFGSGFMDLLKMLVVPLVF
                     LSIIKVIINMKDNNLGTLTFKSLGMLLATTAIAAIVGIIVANIMKLGVGANMPTLVEN
                     QELKEINSLVDTLRGLLPSNPVMAMANGNIVATIIFATFIATSIKRLSKKHFETIKPF
                     IDFIEASYKIIVSVSMTVIKFMPYAVVALLANTITSQGISSIVSVLQFILALYISVAI
                     LFIIHLIFITLNGLNPITYIKNSTEALLLAFTSRSSLGTLPVTIESLVQNHGVDEGVS
                     SFTASLGANMGMNGCAGIYPALMAVTLANMAGVNMDMSFYVMLLIVITISSFGIAGLP
                     GTATMAVSVVISGVGLGSYFPLVGGILAIDPILDMGRTMINVNGAMVSSITVGKSLGK
                     IDKEVFSKKNIS"
     gene            18015..19349
                     /locus_tag="OE968_001072"
     CDS             18015..19349
                     /locus_tag="OE968_001072"
                     /EC_number="1.8.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-disulfide reductase"
                     /protein_id="HCP7218365.1"
                     /translation="MRVIIIGGVAAGMSAAAKLKRIKPEYEVVVYEKTEIVSFGACGL
                     PYFVGGFFNDADELLARTPEKLREAGIDLNIFREVVEVDSESKKIKVKNIKTDEIYED
                     YYDKLMIATGARSIMPPIKNIKLKNVSTLKSLYDGEYLKKLLSNEDNKRVTIIGAGFI
                     GLEAVEACKKLGKDVDVIQLEDRILPQVFDKEMTDVLEEEINRHNVNLHLDEMVVELC
                     GEDKVEKVITNKGEIDTDVVIIATGVRPNTEFLSNTNIKMLKNGAIVVDEYGRTSVED
                     IYSAGDCATIKNIVSNENVYVPLATGANKLGRIVGENLAGREVSYQGSLSSSCIKIMD
                     MEAASTGITEKQAKDLGINVKSKFISDYNQTHYYPGRNKIYVKLIYDADTKVILGGQV
                     AGFKDAVQRANVLAAAIFGKMTTNQLGMLDLCYAPPFARTWDVLNVAGNVSK"
     gene            complement(19491..20408)
                     /locus_tag="OE968_001073"
     CDS             complement(19491..20408)
                     /locus_tag="OE968_001073"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011969064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HCP7218366.1"
                     /translation="MIDLTLLGCGGNVPMPNRFLSSVFINYKGRKILIDCGEGTQVSM
                     KLKKCGFKDIDLICITHLHGDHIFGLLGLLSTIGNSGRTSDLTIVGPVGIVDCIRSMR
                     NLVEYVPYTLKIIENPQGNFSLDNKVLRNLEISTISLEHSIECLGYSFNFRRNPKFDI
                     DKATKNEVPKILWNKLQEGQNIVLDSKQYTPDMVLGELRKGVKISLTTDTRPIESIPD
                     FIKDSDLFICEAMYGDDLDISKAVRNKHMTFREAANLAKLGNVKQLLLTHFSPSLDIP
                     SMYLENATNVFENTILGEDRLSLRLNFDE"
     gene            20616..21500
                     /locus_tag="OE968_001074"
     CDS             20616..21500
                     /locus_tag="OE968_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4846 domain-containing protein"
                     /protein_id="HCP7218367.1"
                     /translation="MKVLKKITILSLITLTLVGCSNGEDKKVVEGSKKIQNSKKDEQP
                     IIVHKDANILKDRYEPPKGFKRVDVEKGSFESFLRNTKLKNYGEKVKYYDGRTKESKG
                     IYDSVFDVDIGNRDLHQCADAIMLMRAEYLYQNKLYDEISFDFVDGFKAKYSKWAQGY
                     RISVKDSGSSWYKATEYSTSYESFRKFMDIVFAYSGTLSLEKELEPVKVEDMKIGDVF
                     IVGGSPGHASIIMDMAENEKTGEKVFMIAQSYMPAQQTQLLINRKNPNLSPWYSLDFE
                     GDLTIPQWTFKRDQLKRF"
     gene            21713..23554
                     /locus_tag="OE968_001075"
     CDS             21713..23554
                     /locus_tag="OE968_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-nucleotidase C-terminal domain-containing
                     protein"
                     /protein_id="HCP7218368.1"
                     /translation="MKIRRYLILVIIILITTSQSFISYGLERFEEITIFHTNDIHGRY
                     AEGDDHIQIGNLATLKKETPNSILVDAGDCLHGLPIVNMDRGKSAIELIKCAGYDYIT
                     PGNHDFNYGKDRLFELSKSANLGENTLKFLSSNIFENGKKVFDSNDIKEIDGIKIGFF
                     GLSTQETKSKTGFKNVEGLEFKNPIESATEQVNELKGKGANVIVAICHIGTNSLSKPN
                     SIDIANEVQGIDLIIDGHSHTKFENGKQVGDTLIVSAGQYLENIGEIKLTLDTNDVEN
                     IKIENKSVRLIGKEEALKYKLDSAVSKKVDEIKEQQEKILDKVIGVTTNTLDGSYENV
                     RTKETNLGNLISDILLDKTKADISLFNGGNIRDTIEKGNITRRDIVDVFPFSNTIVTK
                     ELTGAQIKDVLEHGVKLYPEKSSAFLQVGGISYYFNPKQKEGEKITNIQKEGKPLDLN
                     KKYVVATNDYIASGGDEFPCFSKEPVLKEFGNLESAVIEYIEYKKEISKNVDGRIGIK
                     SKDELISKNHESDLILSENEKNINDNEENLSNNIKSSDSDKNKSLDKTSARESSNLGI
                     SKREAKEKSPKTGDLGFSNSIIIFIVSSTLICLLNFNQKELKDKKSK"
     gene            23859..24566
                     /locus_tag="OE968_001076"
     CDS             23859..24566
                     /locus_tag="OE968_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCP7218369.1"
                     /translation="MNNILLLEDDKSLNRGISFKLKKEGYNVFSAFGIEEAKNIFAKE
                     EICLIISDIGLPDGSGFDFCEEIRKKSDVYIIMLTALDEEVDIVTGYDLGADDYITKP
                     FSLMVLISKVNALMKRVNTVKNYTLLVCDDLFFYYIENKLIIRTDDKEEEIILSKTET
                     KLLKYLMENSMQTLTKEQLLESLWDSSGNFVDDNTIAVNIRRLRQKVEKNPSEPKYIK
                     TVRGVGYMWGERSIKKC"
     gene            24560..25870
                     /locus_tag="OE968_001077"
     CDS             24560..25870
                     /locus_tag="OE968_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HCP7218370.1"
                     /translation="MLKNMNLKDGLSVKDDYIMRRVIVYSVLSVLIVTLVFILFEYSR
                     LHKLYEHQIKNTQNIAGILIEKYPNDEIDIVNSIYNSDYSKVSTGEKAFKKFGYGLEN
                     KMSNDKNFSLYLKSFFKESFFIFLMMFIVVIGIIYYFIRYINKRLSKIYFIVDKMSQE
                     NYLKDTTESEETGYLVEYNEYFKEGIFSKINNCLYELNRSLKIKFIKLEKEKESVKSL
                     VTDISHQLKTPLASLKLYNTLLIEEELEEDEANEFLLTNKASINKLENLINSLVNISR
                     LEISMINIKKEDNDIKNTILNAVKSVTPKAKSKSITLNLNEFNSRIIPHDKKWTEESI
                     FNVLDNAVKYTQVNGEINISVEETANFFKIIIEDNGIGIEKNEFNNIFKRFYRGSADE
                     IESVEGSGVGLYLSRKILEEQGGNIIVSSKVGIGSKFSLFLTTM"
     gene            25987..26670
                     /locus_tag="OE968_001078"
     CDS             25987..26670
                     /locus_tag="OE968_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCP7218371.1"
                     /translation="MKILYTENLSKHYGKGESLVRALDNVDLEINEGEFVAIIGKSGS
                     GKSTLLHMIGGLDIPTSGKVYIDNKNIFTLKEEELAVFRRRKIGFIFQSYNLIPSLNV
                     WENVVLPIGLDGREVDESFIKELLKSLGLENKHDVLPNTLSGGQQQRVAIARALATRP
                     AIILADEPTGNLDSKTSDEVMSILKSMSKKYSQTLVMITHDDSIAQMADRVIFIEDGR
                     VSKVGDKND"
     gene            26663..29050
                     /locus_tag="OE968_001079"
     CDS             26663..29050
                     /locus_tag="OE968_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HCP7218372.1"
                     /translation="MINTTKIAKSNLKQNKSKSILIIITIILSTLMLSSIGIYIVDAG
                     AYQKENTIKYSGNYQGILANVDEKQADILSNHADVELTGEMNGVGVEKLEDDSNISLA
                     YMNEDALKLNSFEFIKGKLPSKENEIVLDSGALKALGYKNKDLGEKIKISYDDYKNDK
                     KIEKEFIISGILKTSEISEAGKYYYAIISESYMRNTRDMSQEDFNIYVKFNDKSNLSI
                     EQAKEKLDKIANDIGLDTINTAVNENYINALKPDMETIMGGVFVGLVIVLSSILVIYN
                     IFYISIVTKVQEFGKLRAIGATKKQIKNIVFKEGFILAGIAIPIGIILGYVLANIIIK
                     SFMDIDVKSSRLPVILSVVVISFISVVLSLLKPMKVASKVSIVDAVRYTGNKISNKSK
                     RKGYKNINLKRLSHANLERNKKRTYMTLASLILSGTIFITVSTALESFDAEKMAREHF
                     PYDIEVRLSGYEMNSDKNPKDNLNILQMDNPLSKDFFNQIKNMEGIKRIESARSVKIG
                     MEDYDVEFKYDLLQSINENDVKSLNKNIIDGKINLERLQTGDEIVITHVDTAKEMGVK
                     AGDKIRLTLYDGDKKIKKEFKVQAIAMGVPSFGIGKDFIDRTLKYDSTSSLGIYTEEG
                     KYQEIKDSIKKIAKNNGFLETDFIDSRIESNKATISFIKIMGYTLTGIIGVIGFMNLV
                     NTMITSIVTRKKELGMLQAIGLTNKQLVKMLNSEAIYYTSGMMIGSILFGGILGYIAV
                     IFLKKTGLSYATYSLPIVPILLMIVCILIAQFITTYLIGRSFNKESLIDRVRYSE"
     gene            29330..30472
                     /locus_tag="OE968_001080"
     CDS             29330..30472
                     /locus_tag="OE968_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--glyoxylate aminotransferase family
                     protein"
                     /protein_id="HCP7218373.1"
                     /translation="MNKKINYAPGPTETRENVRLARAEKTTNPDIDIDFVEFYKKTCE
                     KFGNIIGTKNDVYILSGEGILGLEAACASLTEKGDRVLVIDNGIYGEGFKDFVTMYGG
                     EYVLFSSEYTKSIDIDELKAFLDEDSNFKYATVVHCDTPTGVLNDVSKICPLLKKYGI
                     LTVVDSVAGMVGERLSVDESKIDIILGGSQKAISAPAGLTIVGISQDAKNCIKNRKTD
                     VIGFYCNLNIWEGYYEKKYFPYTMPISDIMGLDKALDNILEEGIENVLNRHEKIAYSV
                     RKSIEEYGLELFLEEGYSNTVTAIKIPESIGALELTDYMLKNYNTLVATSLNQYMDTI
                     LRIGHMGENANLNKIEHVLNVLDKSLSALGFKGNGNLLNLFNKYYF"
     gene            30491..31015
                     /locus_tag="OE968_001081"
     CDS             30491..31015
                     /locus_tag="OE968_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HCP7218374.1"
                     /translation="MEVTAKQKFTTKDMVETSLLIALVFIATKFINIRLPISINGGLV
                     HLGTAMLFISAIVFGGKKGALSGAIGMSLFDLISGWTLWAPFTFIVRGVMGYLLGKIA
                     WANGNNGNNFLINVIGICVSSIWMLFGYYVTEVILYGNFIVPLTSIPGNLMQVLIGLI
                     IALPISKVLKKCIK"
     gene            31115..31933
                     /locus_tag="OE968_001082"
     CDS             31115..31933
                     /locus_tag="OE968_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HCP7218375.1"
                     /translation="MLSVTRYSIKNVRLKPWVKFIWYFETKSNILLNNKLLPTDSIDI
                     ILNLSDVMEYKIENQDYTASNMHFNGIRDKHGFIIQHGNIRVIGISFYPFGLYPFLKI
                     PISEFNRQIVDLEAVSQLFAKKLEESLNPTQSVEKIVLYLEEVLLSILEEDLISNKYV
                     KLLNSFIYVNRYSNIKAFCDDTNINIKTLERICLKYTGYTPKILKRIYRFKMASNQLI
                     YNYKDDELFDFIYENEYYDQAHFIKEFKKFSGTSPIKFIGENKTIKENIKYSYL"
     gene            32011..32322
                     /locus_tag="OE968_001083"
     CDS             32011..32322
                     /locus_tag="OE968_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HCP7218376.1"
                     /translation="MKIITEIVEFNVEENLSKEEFIEIVNDLELKFHSIQSGFIDTEL
                     LYDEKSQKWIMIQHWESIEDLKSASSKMFKDSSTEKFRKALKNQTVKMNIIPQIKSWK
                     L"
     gene            complement(32449..34452)
                     /locus_tag="OE968_001084"
     CDS             complement(32449..34452)
                     /locus_tag="OE968_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha amylase C-terminal domain-containing
                     protein"
                     /protein_id="HCP7218377.1"
                     /translation="MKSQKRFKILDIDVYLQPFESDIKKRMKHYENMKSKTLKNYKDF
                     SSFANAHLYYGFHQTNDGFFYREWAPNADSLSLIGDFNNWNRKSHPLRKIGSGNWEIF
                     IPGQNSLPHKSEVKVQVTANGKTFDRIPLYIKRVIQKDFGGFNGQIWQPKTPFIWTDN
                     DFDLKNITYPLIYECHIGMSTESESIGTYNEFTEKILPKIKKAGYNTIQLMAIMEHPY
                     YASFGYQVSNFYAISSRFGTPEDLKNLINTAHSMGIAVLLDLVHSHAVKNTLEGINEF
                     DGSEHQFFHSGSKGNHPAWGTKLFNYGKPEVIHFLLSNIKFWLNEYHFDGFRFDGVTS
                     MLYHNHGLGVSFDSYEKYFSMNTDIEAITYLQFANELIKEIKPNSISIAEDMSGMPGM
                     CIPIKDGGIGFDYRLAMGVPDFWIKTISNLSDEDWDLGKMWYELTTRRPGEKNIGYCE
                     SHDQALVGDKTIIFWLADKEMYWNMEINSNNHVINRAISLIKLIKLITFSLAGEGYLN
                     FMGNEFGHPEWIDFPREGNNWSYKYARRQWSLSEDNNLKYKQLLNFDKSMLELTKYSD
                     IFIQNSHELIHMDNDKKILVYSKGKYLFIFNFHPNLIQSVDISKFQNTNYKTILNTDM
                     VEFGGNTKKENLRDYDVYFSSTPPSSKMPIASRTAIVLLDSSI"
     gene            complement(34605..35243)
                     /gene="recX"
                     /locus_tag="OE968_001085"
     CDS             complement(34605..35243)
                     /gene="recX"
                     /locus_tag="OE968_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HCP7218378.1"
                     /translation="MGIITKIEQQKRNDDRVNIYVDDKFFIAIFKELVYTFNLKKGNE
                     INEEELKPILDDEMYIKAKNKALNILSHADQSEKKLKEKLSSEFDENIIERVIDFLKS
                     YNLVNDSVLAQKIVNTNVNLNKCGKNRIKQNLYNKGINRSTINEAVSELDKDTEFENA
                     MYLAKKRYERVKKEDKKKIYQKISQHLSYKGFDYDIIKRVLNKLLNFDEYDI"
     gene            35519..36208
                     /locus_tag="OE968_001086"
     CDS             35519..36208
                     /locus_tag="OE968_001086"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HCP7218379.1"
                     /translation="MRSENLVKMAELKNTEKLEKFNRHKGKIKIGILGGTFDPIHYAH
                     LATAEFIRDKYDIDKIIFIPSGNPPHKLCITTDKYDRYNMTLLATESNEDFLVSKVEI
                     ERKKRTYTIDTLKYLKKKYKNADIYFITGADAICSVEEWKDVKKNFELATFIAATRPG
                     ISLLRSQETIEKLTKKYNADIITVYVPSLDISSTYIREQLNEGKSIRYLVPENVENYL
                     YENKLYQYGDD"
     gene            36209..36781
                     /gene="yqeK"
                     /locus_tag="OE968_001087"
     CDS             36209..36781
                     /gene="yqeK"
                     /locus_tag="OE968_001087"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HCP7218380.1"
                     /translation="MNLENINQRLNQMLPVGRLSHSKNVAKCAEKLCEIYGCDKEKAY
                     LAGMIHDCAKYLSDKEIEDYVNKYEIYLDPIEDGNRSLSHSVIGAYICEYEFEVEDED
                     IINAIKYHTTGREDMSLLEKIIYIADLIEEGRKFPVVDTLRELAYGGKLDEALLTSFN
                     NTLMFVINKKEEIHPRTVMARNYLIKEKLL"
     gene            36898..37248
                     /gene="rsfS"
                     /locus_tag="OE968_001088"
     CDS             36898..37248
                     /gene="rsfS"
                     /locus_tag="OE968_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HCP7218381.1"
                     /translation="MTVEQMTKIAYDAIEDKLGQDTVIINIGKVSSLCDYFIITTASS
                     QRQVKAIADNVEDELAKLGLEPRGKEGQGTQTWVLLDYGDIMVHVFNEENRGFYNLEK
                     LWKDAPYIDIDTLA"
     gene            37602..40022
                     /locus_tag="OE968_001089"
     CDS             37602..40022
                     /locus_tag="OE968_001089"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HCP7218382.1"
                     /translation="MSVYNFKEVESKWQKIWKDNNQYKMDTAQTEKPNYYTLEMFPYP
                     SGKIHMGHVRNYSIGDVVARFKKMEGYNVLHPMGWDSFGLPAENAAIKHGIHPHKWTM
                     ENIEEMKEQLNLLGISYDWDKEVATSTPEYYRFTQEIFLKFLEHGLAYKKKSYVNWCP
                     SCETVLANEQVVQGACERCKATVLKKDLEQWYFKTTEFAEELLNDLDTLDGWPEKVKT
                     MQKNWIGKSTGADLVFDIDGTDKSMTVFTTRPDTTYGVTYMVLAPEHELVKELVAGTE
                     YEADVEAFVQKMHTMTEIERTAADVEKEGMFIGRYVINPLNGKKVPLWIANYVLVEYG
                     TGAIMAVPAHDERDRDFAEKYNLDIIDVITEDNKMINSEEFNGLDASEGFEGIIDKLE
                     KEGRGKRTINYRLRDWLVSRQRYWGCPIPVVYCDECGIVPVKKEDLPVLLPTDVEFTG
                     KGESPLTTSKQFMSTTCPHCGKPARREVDTMDTFVDSSWYFLRYVDSNNENEPFSKEL
                     VNRWHPVDQYIGGVEHAIMHLLYARWFVKAFKSMGMVDFNEPFKNLLTQGMVLMDGSK
                     MSKSKGNTVSPMDIIDEYGADTARLFVLFAAPPERDLDWSEQGVDGCFRFLNRVYRLV
                     DELADVVKKDVEFGELNSQDKDMRYTIHSTLKKVTADLSEKFGFNTAISALMELINDM
                     YKYKELDNINEAVIKEGVQTIVTIIAPFAPHLGEELWTMIGKEGSVFDIDWPKYDEKA
                     LVKDEIEVVVQVNGKVRGKLTVNSNISKDEMEKVALEDEKIKGLVEGKTIVKVVAVPK
                     KLVNIVVK"
     gene            40858..41526
                     /locus_tag="OE968_001090"
     CDS             40858..41526
                     /locus_tag="OE968_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HCP7218383.1"
                     /translation="METVTNNQSGVEIQLSLFEAIKDLLLINPIFLLGIILIGIFLVV
                     IFKKNSDIPKVKTSILSLAMYYYLCLTLSHIVGIPTFGEYIRLSQLGETFFNPNINLI
                     PFSDGFSLSFILNILLFVPLGFLCPLISKTFERLRNTFLIGFGLSLFIETIQLFTLHR
                     ATDIDDLLTNVIGTIIGYFCFKLIAKLRIVKLHSDDDSMEQDYTVCIPIAIIIVALIL
                     GFFS"
     gene            complement(41844..42116)
                     /locus_tag="OE968_001091"
     CDS             complement(41844..42116)
                     /locus_tag="OE968_001091"
                     /inference="COORDINATES: protein motif:HMM:NF012798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HCP7218384.1"
                     /translation="MSKHQFKSVSTFFTKKNVSQFYKKNNLKKIRIHDLRYTSATLLL
                     LGGTNMKVVSERLGHTDIKITMNRYSHVLKEMDKEASDNLSELLFK"
     gene            complement(42347..42768)
                     /locus_tag="OE968_001092"
                     /pseudo
     CDS             complement(42347..42768)
                     /locus_tag="OE968_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431042.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(42787..42885)
                     /locus_tag="OE968_001093"
                     /pseudo
     CDS             complement(42787..42885)
                     /locus_tag="OE968_001093"
                     /inference="COORDINATES: protein motif:HMM:NF026008.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Arm DNA-binding domain-containing protein"
     gene            43168..44538
                     /locus_tag="OE968_001094"
     CDS             43168..44538
                     /locus_tag="OE968_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp29"
                     /protein_id="HCP7218385.1"
                     /translation="MKLKKLLSLGLAVSMFAAGPISANALDTIYTIQGKDKYETAALI
                     ADEQNYTTAILINADSTMADGLSASGLAGATNAPIFLTKKNNIPNATLKRVEKAKKVY
                     IIGGESSIDKATETLLKDKGIEAKRLQGSDRIKTSYNVAKEINSINKVNKVILTNAFK
                     GEPDAMSAAPVAVRDKAAIVLTDGKSVPFNTTGVESYVIGGTSSMSDKLVNDTNSTRL
                     GGVDRYDTNKKIVNKFYNGAKEFYIASGTDLVYALVASPMAKNNPIVLVDIGSNKDIL
                     KNAAKVTGIGNLSDKIMLECENTINNISLPSSNKNIICGLKIDFDSKHIIWQDKGSYL
                     ECYDDNLEYYTEKYKDPTVPINIENTSTQNLDVTKLKVYGEANSTLYMGQYAKIKMDF
                     NSFGVLKPGEKCTIYLDIISLDPSRSMTLTFSYVGDKENYKYEQGLASRILFYNPDGE
                     DFFEYK"
     gene            44897..45055
                     /locus_tag="OE968_001095"
     CDS             44897..45055
                     /locus_tag="OE968_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218386.1"
                     /translation="MDNFLQGILASLSASLIVYIASKLFRKRKKPLKAATKSGWEFDL
                     KIRFHKTK"
     repeat_region   45341..45698
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=45341..45369
                     /rpt_unit_seq="gttttatattaactatatggaatgtaaat"
     regulatory      complement(45840..45937)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            46163..46546
                     /locus_tag="OE968_001096"
                     /pseudo
     CDS             46163..46546
                     /locus_tag="OE968_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431032.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
     gene            complement(46735..47730)
                     /locus_tag="OE968_001097"
     CDS             complement(46735..47730)
                     /locus_tag="OE968_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HCP7218387.1"
                     /translation="MSIKKKVAIVFTGGTISMTVDDKVGAAIPTLSGEQILSMVTNID
                     KVADVEVFNFDEIPGPHITPYRMMELKNYVNDLLARKDITGVVITHGTDSLEETAYFL
                     DLTIDNIKPVIVTGAMRSSSELGYDGSSNLSASVCTAVSKDAMGKGVLVVLNNEVLLA
                     SEATKTNTLSLNTFKSLTSGPLGIIDCNELVLTRDIVNRTIIDTDKVESKVALFKAYV
                     GENADFIRFAVDSGYKGIVIEAMGRGNIPPQMLSGVEYAREKGLPVVIVSRCHSGRVF
                     DSYGYFGSGRDLKNLGCIFGGDLPGQKARIKLILALGKTDNLDEIKDFFEKGIYC"
     gene            complement(47851..49479)
                     /gene="aspD"
                     /locus_tag="OE968_001098"
     CDS             complement(47851..49479)
                     /gene="aspD"
                     /locus_tag="OE968_001098"
                     /EC_number="4.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate 4-decarboxylase"
                     /protein_id="HCP7218388.1"
                     /translation="MKNHTYKEIKNIYGKISPFEFKDKLIDIAKYTAKENNRELLDAG
                     RGNPNWTCSTAREAFFTFGHFAITETRSNWDLGHLAGMPQKKGIKERFFKFINENIDM
                     PGAYLARDIINFGINELGFDGDEFVHELADGIIGDNYPLPDRMLPHMEKIVHDYLVQE
                     MKYDISGKYGDVEIFAVEGATAAMCYIFDSLMANELLKKGDTIALMTPIFTPYLEIPN
                     LPRYDFKVVNINANEVDEKGAHTWQYTKKELEKLRDKSIKALFVVNPNNPASIAMDET
                     SCNNLIDVIENYNKDLMIISDDVYGTFVEDFSSLMSKLPYNTVGVYSYSKYFGVTGWR
                     LGTFALHKKNVFDKKINDLTGELKKSVDKRYSDMSLNPSSLSFMERVVADSRLVALNH
                     TAGLSTPQQVQMAFFSAFALIDKVDAYKKLNMSICHRRQKLLFEALELPINENKNNAA
                     YYTQFDIEEWAKLNYGEDLFKFISKTASPVDVLYKLANDYSVVLLSGNGFYGPEWSIR
                     ISLANLYDEAYTKIGKAIREILNGYIVEWQKIKK"
BASE COUNT        19043 a         5640 c         8312 g        16624 t
ORIGIN      
        1 acgtgaaagt gtaagaagtt cataagagaa ctgcataggt agtagcgaac ttatgtgaac
       61 gacaacctca aaaatgataa aagttaagaa cttacggttc ttatatatgt tatttaaaaa
      121 taaatataaa aaaccttcaa aatacttgtt ttaagtaatt gcatatttta atattatgat
      181 aagtgatgaa aaatggaagt tactcatggt agaggatatg catatagtat gtcaaatata
      241 gacatccatt attatgggga gacatctttg gaatcctagt tatttcgttg ctactgtatt
      301 agaaaataca gaggagcaga taggaaaata tattaataat cagaaaaaac aagtaaagtg
      361 aggtgatagt agtggaaaaa gcttataagt ttagaatgta tccaaataaa aaacagcaag
      421 agttaattaa caaaactttt ggatgttgta gatttgtata taataagtat cttgctaaaa
      481 gaatagaagt ttataaaaac gataaagaaa cttttactta taaacagtgt agttctgatt
      541 tgaccaattt aaaaaaagaa ttaaagtggc ttaaagaacc tgacaaattt tcactacaaa
      601 acgtcttaaa agatttagat aatgcatata aaaaattctt taaagaaaaa gcaggatttc
      661 ctaaatttaa atcaaagaaa attaatagat tttcatataa aactaacttt acaaatggaa
      721 acattatgta ttgtggtcaa catataaaac tacctaaact tggtatggtt aagataaggg
      781 ataaacaagt acctcaaggt agaatactta atgctgctat atctaaagaa ccaagtggta
      841 gatattatgt atcattatgc tgtactgatg tagatattga agcatttgaa aatactaata
      901 atcagatagg tttagattta ggaattaaag aattttgtat ctcaagttgt ggagaattta
      961 tagaaaatcc taagtatctt aagaagtcat taaacaagct tgctaaatta caaagagaat
     1021 tatcgagaaa aacaatcggt agtttaaata gaaataaggc aagattaaaa gttgcaagac
     1081 ttcaagaaca tatagctaat caaagaaatg attttctaca aaaactatct actaaattaa
     1141 taaaagagaa tgatattatt tgcatagaag atttacaagt aaagaatatg attagaaata
     1201 gtaaactatc tcgcttaatt tcagatgtat catggtcaga atttattcgt caattagaat
     1261 acaaggctaa ttggtatggt agacaaattg taaaggtagg taaattcttt gctagttcac
     1321 aaatatgtaa taaatgtggg tataaaaacg aggaagttaa ggacttaaat ataagagaat
     1381 ggatttgtcc tagttgtaat gaaactcacg atagagatat aaatgcaagt ataaatatat
     1441 taaaagaagg attaagacta ataacgattc aaaataaata acatatgtaa gaaccgtagg
     1501 aactacgggg atagcctgtg gagaattagt aagacatatt ttagtatgca aaattctatg
     1561 aagcaggaac cctgtgactt tagtcatggg aggttcagtt tatttcaaat aatattttac
     1621 gtaatccatc tatgttaatt ggattaatag cagcatttgg tcttgtacta cagaagaaga
     1681 aagcatctga tgttataaag gggtcactac ttgcagcttt cggaattata attatggaga
     1741 ctggaacagg tatgttagtt agttcaatag caccaattaa tggagctttc caaagtataa
     1801 gtggtggtgc agtaacaaaa ggtttaagtg atgttacttt tactgcaagt tatggtggaa
     1861 ttataggttt agcaatgttt gcgggtttag ctattcacct aatgatagca agatttactc
     1921 ctattaagac aatcttctta acaggtcaca tgctttattg gttcccattc atatttgtag
     1981 cttcaggagt tgaagctgga ttaaatggtg gagtattaat aacttttgca gcagtattat
     2041 cagcactcta ttggtcaata atgccttggt tattaagaaa atatgtgttt gatgttatag
     2101 gagatgattc ttttacatta ggtcatccat ctggttgttt agcacttata tcaggatttg
     2161 ttgctaaatt agtaggaaat aaagaaaaat ctacagaaga tataaacata cctcaaagtt
     2221 tatcattttt tagagaaata tctataagtg gtggaatggc agtgttttta atgtttatag
     2281 ttgttgggat agtaatacca ggtgcgttta aagatagtaa tgagtttatt ggaacgtatg
     2341 caataaagca aggtctttct tttggagcag gtcttataat aatgcttcat ggggtaagaa
     2401 tgctaataaa tcaaataatg ccagcatttc aaggtatatc tgaaaaagtt gtgccaaatg
     2461 cactacctgc ttttgactgt ccaatattat ttaattataa accaaatgct gtattaatag
     2521 gattcttagt tgctatgcta acatctacag ctatgatttt aatatataac tactttaatg
     2581 tatttaattt gctacttata ccacttgtta taacttcatt ctttgagtgt ggagcagcag
     2641 cagtaatagg agaatcacaa ggtggtatac gtggagctat aataggtaca gctatagctg
     2701 caatatttat ggtagtttta gtaggaatat ctgctgtaat ttactcagga actattcaaa
     2761 attggatact aatatttgga ggtaatgacc tttcattatt tggtataatc agtaggttta
     2821 taggttcact atttggagga atattataga tatgaaattt aaatacatag atgagataag
     2881 aagattaatt gatataatag aaaacgaaga aaaagtcaat atggaaaaag cagtacaaat
     2941 ctttgttgaa gcaatagaaa gtaaaaatgc tatattttca tttggagctt cacatgcagg
     3001 aatattaaca gaagaattat tctatagagc aggtggctgt gttcttataa atccagtatt
     3061 tgcaaaatct ctaatgttag atacagcgcc tataactcac acaagtaaga tggaaagatt
     3121 agaaggatat ggtacagctc tagctgataa aactccaatt aaaaaaggag atgtagttat
     3181 agttcattca gtatctggta gaaatccagt aagtatagag tttgctatga aagctaagga
     3241 aaataaggca atagtaatat gtataactaa tttaagttac tcaaaaagtg tatcttcaag
     3301 acattcttca ggaaaaaaac tttatgaagt atgcgattta gtgatagata atcatggtca
     3361 aaagggagat gcctgtgtag agatagatgg attaaaccaa aaagttagtc caacttctac
     3421 tgtaatagca actactgtga tgaactctat tatagctcaa gctactcagg aattagttaa
     3481 taaagggcta aagaatcctc cgattttcta tagtgccaat attgatggtg gagatgagtt
     3541 aaataagaag atttttgatg aatataaaag tgtaattcat tatgaatatt aaggttaaaa
     3601 aaatatgtta atgaactttg aagtttatca acaaagaata ttaataatat ataataaatg
     3661 ctatcattta aaagctgtag gtaaaaatct acagcttttt attattgtag attaaaaaga
     3721 tgcgtaatta aattttaaat tggagaaaat aaattggaag gtatcaatta taaatattag
     3781 aaacgttgtc atagaaaaaa actatattaa aaaaaagtac atagaaaaaa ctgattagac
     3841 aataaataca tgctttgata atattttaaa tggaatgaaa atgtgtagaa ttataatgaa
     3901 aaaagaaaat aaaaatgaaa aaagaaaata aaatggaggg aataaaagtg ggtatgttaa
     3961 aaaaattatg ttcactagct atggtagcaa ttatgactac aacacttata acagggtgtt
     4021 caagtggaaa tggaaaagat tcaaaaaagg atggcgaaaa agaaaaacta gttctttgga
     4081 tgccaccagt agaaaataat atgaaggaag tttgggaccc tattttagat aaatttgagg
     4141 aaaaaaataa ctgtgaagta gatttacaga taattccttg ggataattat tctgaaaaat
     4201 ttgcaacagc tataagtgct ggcgaaggtc cagatgtagg atatatgtat gcagaaatgt
     4261 atccacagtt tatagaaagt ggagcagtag aagatttgac taactatgca actaaagagg
     4321 ataaagagca atctatttat ataaaaacat ctgaaatgat gggtggaatg tatggtatgc
     4381 cattccaagc agcaaatcca ggggtattat actataacaa ggatatttta gagaaactag
     4441 gagaaaaacc tcctaaaaca tgggaagatt ttaaaagaat ttgtaaaaaa gcaacgcaag
     4501 atactgatgg tgatggaaag atagaccaat ggggattagc tcagggatgg ggagctaaaa
     4561 cttttggtaa cttaaactgg aactggtatc cttatttatg gcaagctggt ggagatatat
     4621 ttaatgatga tttaaaatcg gttaaattta atgataagag tggtttagaa gcagctaatt
     4681 tcttaaaaga attacaagca tatgtgcctg aagattcttt atctaaagat agtaatgaaa
     4741 tgatagaaag cgtatttgga ccagggaaag cagcatttac aataatgtta tcttctgctg
     4801 caacaagtgt atttgatgaa tcattcccgg atttaaattg gggatttgta actggactag
     4861 aagataagaa agcagcaact tttggagcag tagaccattt atctttaatg tcatctgcta
     4921 aaaataaaga acttgcatac aagttaatac aacatatgtt aagtgttgaa tcaatgacag
     4981 aatttcataa agcaatacca agagcaccaa taacaaaagg tgaaccatat caaggtgatg
     5041 aaagattcaa agaaatggtg gaaaatgaca aaaatgtata tagaccatta gtagtaggac
     5101 ctcatggagt tgaaatatat gaatatttat ggaaagaact tcaaactatg atttcaggag
     5161 ataaaactcc aaaacaagcg ttagatgatg ctgcaaaata ttcaaatgat ttattagcac
     5221 aataaaagtt taaagctgta atatgttgta aaggacttta cagattaaaa ttagcattgt
     5281 atttataaat acaatgctaa tatttatatt ggagaggata aaatggaaaa cttagttaga
     5341 gagtttgaag aaaattcaaa aagaaaaaaa acaaaattaa atattaaacc atatatgtat
     5401 atattgccat tgggaataat tttagtggcg ttttatgtga taccaataat aatgtcaata
     5461 tactttagtt ttacaaagta taatattatt agtccagcta cttttatagg tttagaaaat
     5521 tataaaaaat tatttacaga tgaaacatta aaagtatcta ttataaatac tattaaattt
     5581 actgttgttg tagtaccttg ccaaactata ttatcattga ttttggctgt ttggattaca
     5641 ggaaaaggaa atagtaaaat agcttcattt gctaaaggtg ctatatttat accagtatta
     5701 tcatctatgg ttttgatagg tatggtatgg agggctttat tgaatggaga aggttctatt
     5761 atatatcagg tattaggtgc ctttggaata gaatcatcta aacttttagg agatagtaag
     5821 acagcattac ctacacttat gtttatatct atgtggaaaa atatagggta ttttatggta
     5881 atttatattt cagctataat gaatttacca aaacactgct atgaagtagc gaaggttgat
     5941 ggggctacaa aacttcaaga atttataaaa ataactgtac ctttattgaa accaactaca
     6001 ataatggttg tatttttagg gtcgatatgg tcattacaag tatttgactt aatttatact
     6061 gtgacaggtg gaggtccagg tatatctact atgagtatag ttatgcatgc atttaactta
     6121 aactttaaaa actttaattc tggatatgca atgactgtag caaacgtatt atttttgtta
     6181 atagcagtag tttcgatttt acaaaataag cttgtaagac gagacaattc agatttttag
     6241 aaaggtaggt ataatatgaa aacagcaaga agattattaa gtgatggttt gcttttattt
     6301 atagcgtgtg caagtttggt accttttata tacatgttga taatatcatt gaagataaca
     6361 tataactcat atagtttgga tatatctttt tcaacagtaa cccttcaaaa ctatatagat
     6421 atttttacta aaaaaggatt tgcacaatat ttttttaata cagcaatagt atctttttca
     6481 ggtgtattat taaatttagt atttagtaca ttagcaggat attcttttgc gaagatggat
     6541 tttaaaggta gtgataagtt atttttattt atgataatga ctttaattat accttcccaa
     6601 gttacaatga taccactata tataataatg aaacacttag gatggataaa tagttatctt
     6661 gcacttatta tgccaatacc aactgcattt ggcgtattta taatgagaca agctatttta
     6721 ggagtaccaa aagagttatt agaatcagca aagatagatg gttgttcgga ttttagaatt
     6781 ttaatacaaa tagtgttgcc tttaattaaa ccagcattaa ttacactagc aatatttact
     6841 tttatgggag catggaacga gtttatgtgg cctcttatag ctacaactaa agatacaatg
     6901 agaacattaa cagttggatt atctactctt aagacattcc agataactaa ttatggacag
     6961 atgatggcag gggctacaat aacattttta cctccattta ttttctattt gattttacag
     7021 agtaaatttg ttgaaggtgt gtctttgtct ggtataaaag gttaaatagt ctaatttaat
     7081 aatatataaa gaaacttata taaatatgga ggaatttaaa ctatggaaat ttcatatgta
     7141 ctgaaagatt gcacattcaa acacaataaa tactcagttg tagaagctga aacttggaaa
     7201 gataaggatt tggatattgt agtagctaaa ggtgaaaaat ttgcatttca aattatgtta
     7261 aaagcaacag aagaatttaa ttgtacaatt gataaaagta gtgctatatc atggaaaggc
     7321 ctgggaaata gagtaaggtt agcattaaat atgcctaata gtttagaaaa taattttagt
     7381 ataaatatat taggatatgt tcaagatgat acaaaggcat ttgtgaatga tgctatttta
     7441 agggataaag atgtgttagt agagcaatat ttgcctcaaa cattttggat tgaaggtcaa
     7501 gtaccagaag attttgaaga aaataacctt gatataggta ttgatatatt taaaagcttt
     7561 ggatatgaag acgaagaaaa agtttgtaca attgatgttc ctgtaaaagt aagaaatgtt
     7621 gtgctaaagc ctttagatga aagcaagttc tttttagatt tatggcaaca tccaagctgt
     7681 ttagctagaa tgtataaagt tgagttatgg tctgatatac attttgaaat agtcgataac
     7741 tatttaaaag aattagcatc tttaggagaa aaagttgcaa cagttatagt ttcagattat
     7801 ccatgggcag ggcaaagttg ttataaagtt tataaaaatc catcaaactt atatgaatat
     7861 aacatggtaa gtgtatcaaa aggattggat ggaaagatta aatgtaactt tgagagtatg
     7921 gataggtata taagcatagc tgataagtat aaaatggcta aggagataga tttatttggt
     7981 ctattaggta attggtgtgc tggtgagttt ggaaatcctg tagaaggtta taaggaccct
     8041 ataagagtaa gatattttga tgaaaaggat aaagtattta aatttataaa caatacaaat
     8101 gatttaaaag aatatatagg attagtatta aatcatttaa tagagtgtgg attatgggac
     8161 agagtaagga ttatagctga tgaaccaaat aatccagaag tagtcaaaga gtgtatagaa
     8221 tttataaatt ctactgtaag cactcatcaa gttaaatata aatcagcaac tcacgaccaa
     8281 aactttttag acagagctaa agatgaaatt gatgatatgt caataaattt aaaacttact
     8341 atacaaaatt ataaagatat agaaagtctt aagaaaaaaa tcaatgacaa gggtgggata
     8401 ttgacttggt ttgtatgctg ttttccagag aaaccaaata gttttttaag ttctcctttt
     8461 gtagaaaata gaataatagg atggtatact tattactttg gtcttgatgg atttttaaga
     8521 tgggactata atttatggac agaagaccct tggaaagatt caagttacaa attccctatt
     8581 tggaaagctg gagatatgtt ctttgtttat cctggaaaag atttaaagcc agttagaagt
     8641 gtcagaatgg agaatttaag atttggaata caggactttg agttatttac aatgttagaa
     8701 aaagaaaagg gaagagagta tatagaagtt gagcttatgc aagaattatt aaataaaaaa
     8761 gaaaatgctg aaattaaagg ttttggtgac atagaactag gatattcact tgataattgg
     8821 ggatatgata aagttaaaaa atatgtatta gagttgttag acagagtata aaaaatataa
     8881 gagtgtctca aaatgaactt tttagttcat gaggcactct ttttgtatga aatcaatata
     8941 gtttcattgt ttcaacaatg aaaaatagga ttatttctat tctaagacag ccctttagtt
     9001 ttttagttgt attcaatgtt ttaaaactaa ctataaacgc tataaagttt ataaatgaca
     9061 ataattatat ataacatgat gtactttaat ttgctataat agggattgaa taatattata
     9121 tggaagataa cattgtttgg ggggattaat ataaaaagaa taggtattat tataatgttt
     9181 tttttaagta tatcttttat tggattttat cttgtaataa gagataacag tgatacagtt
     9241 aagatgcaac gagggataaa tataggtaat gcactagaat cacctaagga ttttccgtgg
     9301 gatgtaaaaa tgtcaaataa gttttttgat gatataaaag atgcaggttt tgacacagta
     9361 cgtataccag taaggttttc tgattatacg tcagattctg ataattttaa aattgatgaa
     9421 gaatttttta aaaagattga taaatatgta gattatgcat tggataaaga cttaatagtt
     9481 gtgttggatt tacaccattt tgaagaaatt atgaaagaac caagagttca taaagaaaag
     9541 tttttaaaaa tatggcaaca gatagctaat aggtatcaaa aatatgataa aaaattggta
     9601 tttgaattat taaatgaacc taaagaaaat ttatattcac agttactaaa cgaatacatt
     9661 gaagaagcaa taaagataat tagaaaaact aaccctaaaa gaactattat agtaggacca
     9721 tataatttct atcaaattga ttatttgaat gaattaaata ttcctaaaga ttctaatata
     9781 gtagtttcct ttcactatta cgagccaaat gattttgcat ttcaaggaaa tatatatcat
     9841 aagggatttg agcacttaag caatattact tgggaaggaa caaacgaaca aatggattat
     9901 ttaaaaaaaa ggtttgatac tgtggaaaat tgggcaaata aaaataaggt aaaaatcttc
     9961 ttgggtgaat ttggaataac aaaagaggca ccagaagctt caagaagagc atggataaaa
    10021 gctgtaagag aagaagctga aaaacgaaac ttttcatggg cttattggga gcttgcatct
    10081 ggatttggta tatacaatca aattgaaggg acttgggata gagatatatt aagtgcatta
    10141 atagaaaaga ggtgatttta tgaagaaaaa ttcaaaaaag atacttataa ctttaactat
    10201 tattactaat gtcatatata tattgtggag aattttttac acagtaccta aagaagaagg
    10261 gaagtttgcc ttaatatgtg ccataatact tctttttgta gagataatgg gcatgatgga
    10321 aatgtttgtg cattattatg gtatgtcaaa tattgagtac cctgaaaaac caatcataag
    10381 tgaagaactt tatccacatg tagatgtatt cattgcaaca tataatgaat ctgttgattt
    10441 ggtgagaaaa actgtaaatg ggtgtattca tatgcagtat ccagataaga aaaaggtaca
    10501 tatatacata tgtgatgatg gaaatcgtga agaaatgtgt attctagcag aaaaaatggg
    10561 tgtaaattac ataactagaa ctgaaagaga aggagcaaaa gctggaaatt taaataatgc
    10621 aatgcaacat acaaattccc ctttgattgc tacatttgat gcagatatga taccaatgca
    10681 tgacttttta attgctacag taccatactt tttgaaaaat gagcaagcta aaaaagatgg
    10741 agaaaaagag gagtatgaaa aggttggttt tgtgcaaact ccacagagtt tttataatcc
    10801 agacttgttt caatttaatc tgcactctga aggaaggatt ccaaatgagc aagattattt
    10861 ttacagagac attcaattgg ctagaaatag gacaaattct gtaatttatg gtggtagtaa
    10921 tacagttatt tcaagggaag cacttgaaga agttgatgga ttttatactt attctattac
    10981 agaagatttt gcaacaggta tcttaattca aagtaagggg tatagatgtt atgctattcc
    11041 agaagtacat gcatcaggtt tatctcctac agatttaaaa agtcttatta agcaacgtga
    11101 aagatgggca cgtggatgta tacaaactgg tagacgtcta aatattttgt ttaggagagg
    11161 tttaggtttt tggcagaaaa taagttatat ttcttcaatt acttattggt atgcaagtat
    11221 aaaacgcttt gtatatataa tggcacctat tttattttct gtgtttaatg tgattgtagt
    11281 aaaatgtacg ttacttcaag tattggtatt ttggttgcca atgtatattt taagtagttt
    11341 atctcttaaa atattttctc aaaatataag aaatactaga tggaccaata tatatgaaac
    11401 tataatgttt cagtctttaa tgccagcagt aatacttgaa acgtttgcaa tatctaaaaa
    11461 taaattttca gtaacaaata agagtaaatt agaagaaaat agaatgtata agtttttaca
    11521 gggaatacct tattttattt acatggtctt atctatcata ggaattttaa aaatgtttgt
    11581 agcaatattt aaaatgagtt caatgacata ttcagttgta ttattttggt tgattggaaa
    11641 cctttttaac cttgttatgg ctacattatt tatatcaggg agacagcagt taagaaagtc
    11701 tgagcgttat attgctgaaa ttgattttaa gttaaagcaa aattcttatg ttctttcttc
    11761 aaaaacaatt gatatatcag aaaatgggtt tgcatttttg ctagaaaatc cagaatatat
    11821 ttccccagaa gaagagtttg aggtagagtt tagagaaaaa tctggaaatg aaatgtatat
    11881 agctaatatg aaagcaaaga ttgttaatgt tgtggaagta aattcaaagt ggaaatatgc
    11941 agcttatatt acacatattg aagatagtga aatagataat tggatgtgta ttgttcacga
    12001 tagaatacct actttaccaa tgacaatatc taatcaacta ggtttctttg atgatttgca
    12061 aattaatgta aaaaaacgta ttgaaaaaac tagaacatta tcacgaagaa gtccaagaat
    12121 caatatgaat tttcagatgg atataaaaaa tacaggtaaa ttaagaatag tgaattttaa
    12181 ttatcaatat gtattattaa attttgagaa taaaagtatt tatcctaaag aaatagcatt
    12241 ggaaattaat gaaaatattg tgttagaatg tgatttgtgt gagggtaaaa ttgatgaaag
    12301 aggtatctta tataaagtaa ataacattga cagcataatg caaaatttct ttttaagaga
    12361 tgaaatgatg gattggatat tacaaaataa gaaaattctt gattcaaagc ctagtgaaaa
    12421 gaaggaaaaa agtatagatg agtttgaacc catggaatat atttaggaga gatgaaatga
    12481 agactttaaa agtgtttttt tgttctacaa aatatcttat tttggtgttt atttttttta
    12541 taaatactac ttttataagt tcagcaacaa gtgataaaat tttagattta tcctttaaaa
    12601 agatagagac tgacttaagt tctaagatta catatgagga tacaggtgta aaaatagaaa
    12661 cggatagttc taaaagcgat aaggaacgtt atttatatat ttaccaaaat ataaaagaaa
    12721 attggagcat gtataataat ttttatattg aaattcaaaa taaaaataaa agttctcaga
    12781 gaataaattt aagcatacaa agtaaaaata tgcttgaatt tagattaaaa gaaggtagtg
    12841 aagtattttt agaaggtaaa aatataatat attcagataa aataaaagaa ggatgcatag
    12901 aagtaccagg tgaatttgaa ggcaaaattt atgtgaactt taatagcctt ataaatgagg
    12961 aaagtaatgt tgtgctggac tcaaatatgc tttcaaacat tgttagttgg ggaattacgt
    13021 ttattccatc tgatgaagaa cataatattg ttattataaa aaagatatct ttattgtctg
    13081 aagagaaatt aagattttta aataatatta aaataattgg cgatgaagaa gtacaaatac
    13141 cagtattggg tcaaagtata agtcagtatg aggtattagg tcttaaaagt gattctaaaa
    13201 ttaagtactc tcttatggga aaacaagata atgtgagtat atctcaaaac ggtaaattaa
    13261 cattaagtaa taaagccaaa cctggacaaa ttattttaca agttaatgtt gatgataagt
    13321 ttaaaattgg aaagaaaata acattaactg aatcttggag tattaataaa aaagataagg
    13381 atggtgttcc atatacatta gtatctcctg agcaatcacc aacagtacaa gatatgaaaa
    13441 aaataaattt tatgaataat atcataacgt ttgttcgaat tttatttgta tctctagtaa
    13501 taatatgctt tggaatatat ttatattgga aaaaatgttc aaaaactaag taaagagagg
    13561 aggttagatt gtgttatttt caagtttaat ttttttattt tattttttac ctataacttt
    13621 ggttttatat tatgtattta ggtttaaccg aacgatacag aacatgatat tgcttgctgt
    13681 tagtttattt ttttatgctt ggggagagcc aaaatttgtt gttatcatga tagtttccat
    13741 aataatgaac tatatatttg gtttactggt agatagatat agggaaagta aaataaaagt
    13801 aaaagttttt ttagttttga tgtgtgcata caatataggt gttttattta tatttaaata
    13861 tctagctttt gcgctaagaa atattagtga acttattagt actgaattga ctatacctaa
    13921 tattatttta cctataggaa tttcattttt tacatttcaa ggaatgtctt atgttataga
    13981 tgtatatcgt agacatggag aagtccaaaa gaatcctttt tatgtgggac tgtatatagc
    14041 atttttccca caattaatag caggtcctat agttagatat gagagtgtgg cagaacaaat
    14101 tctcaataga aaagaaactt ggaataaatt ttctattggt acttgcaggt tcataacagg
    14161 tctaggtaaa aaagtattaa tttcaaataa catggctata gtagcagact atatttacac
    14221 tatgaatagt caaggagaaa tagctgcatc acttgcatgg cttggttcaa tagcctatac
    14281 tctgcaaata ttctttgatt tttctgctta ttcagatatg gctataggct taggtcttat
    14341 gtttggtttt aaatttgaag agaactttaa ttatccatat atatcaaaat caattagtga
    14401 gttttggaga agatggcaca tttctttggg aatgtggttt aagagctata tatactttcc
    14461 gcttggaggt tctagagtag caaataaaga tattatgatt agaaatatgt ttatagtgtg
    14521 gttattcact ggaatatggc atggagcaga atggacattt gtaatttggg ggattttaaa
    14581 ctttgttttc ctaattatag agcgatttat aatgtttgaa aagattgaaa atcacaattt
    14641 tataaaacat atttatgctt tattagtagt taattttgga tgggtattgt ttaggtcacc
    14701 taatttaaaa gaagcatata attattttaa agctatgttt ggaggcaatg gagctatatg
    14761 gagtgattat acatatatgt ttttaaaaga atactgggtt ttctttatat ttgcatttat
    14821 ttttagtgta cctattgcaa agaaaatcaa taagtttgtt gttgaacaag ctaaatatag
    14881 tatgatattt aacgtatttt atccaatctc agctatttta ttgtttttta tttctgtgac
    14941 atatttagta actggaagct ataatccatt tatttatttt aatttttagt tgggaggaaa
    15001 agtatgaata gattttttaa agtaagatta ataactgcaa ttatgttctt aattatttta
    15061 ttcgctttct ctatctttaa tgtttgttat tctggaaaag atacgataca ggaaataaaa
    15121 aattcaatag ctgaaaaaag tagtttaaaa gatacaatat catctattga taatacagtg
    15181 aatgacaaag taatatacaa aaatacgttc attgaaactt atggctattt acaaaaatta
    15241 atgggtaaaa atgagttttc aaaatttagt gttgtaaaag atacttctgg aaagatgcat
    15301 tatacatatt ttgctaaagc tccaaatcca gttggtgtga tagcagatag ggtaagaaaa
    15361 ttttctgatg aaatggaaaa gcaaaacact aaattggttt acctaatgac tccagataag
    15421 tatataaaag gagtgacaaa atttccaaaa ggaatacctt attcttatag taatgagaca
    15481 gcagataatt ttttaaatca actaaaaaag tataatgtgg actatattga ttttagagaa
    15541 aatattttaa agagtggtat tccaaaagat gatttatttt ttaaaacaga ccatcactgg
    15601 aaagtagaaa cttctttttg ggcatttgga gaattagttg agcaacttaa taaaaaatac
    15661 aatatgaatt tagatgaaaa tcattattat agagataagg acaattataa ttcaattgta
    15721 tatcctaagt catttcttgg ttctatggga agaaagactg gtatcttata tggtggtata
    15781 gatgatttta cattaattta tcctaaattt aagactaatt atacttatta tacagattct
    15841 aaatctcaaa aatttgaatt aaaaggaagg tttgaagaga gtttaatatt atcatatcct
    15901 tttaatgcag accttgattt aatggatggt caatcagata agtattttac atatttattg
    15961 gggaacagac cattagttaa aataaaaaat atagaaaatc cagatggatt aaaagtgctg
    16021 tttgttaaag attctctaat tgtaccaaca gcagcatttt tttcctctgt ttgttcatct
    16081 atagatatga tagaccctag atattatgat ggagatatac tagaatatgc aaaatcccat
    16141 gactatgact ttgtttttat atctgtatat ccccaaaatc ttacaaaaga attttttccg
    16201 ttttgtgagt aaatttctaa aaaagttttc tgataaaata aatggctaac tggtaaaaag
    16261 ttagccattt attttgagtg ttattctaag aaatattttt tttactaaat acttctttat
    16321 ctatttttcc aagtgatttt cctacagtaa ttgatgatac catagcacca ttaacattta
    16381 tcatagtacg tcccatatct agtatagggt ctattgcaag tataccacca actaatggaa
    16441 aataagaacc aagaccaact ccagagataa caactgaaac ggccattgta gcagttcctg
    16501 gaagaccagc tattccaaac gaactaattg ttataacaat taacaacata acataaaagc
    16561 tcatatccat gtttactcca gccatattgg caagtgttac agccattaaa gcaggatata
    16621 tacctgcaca accattcata cccatatttg cacctaaact tgctgtaaag cttgatacac
    16681 cctcatcaac tccgtgattt tgtactagac tttctatcgt tacaggcaat gttcctaaac
    16741 tagaacgtga agtaaatgcc agaagtaaag cttcagttga attttttata taagtaatgg
    16801 gatttagacc atttaaagtt ataaaaatta aatgtataat aaataatatt gcaactgata
    16861 tataaagagc taatataaac tgtaaaacag atactattga actaatacct tgtgaagtta
    16921 ttgtatttgc aagcagagca accacagcat aaggcataaa tttaataaca gtcatagaca
    16981 cacttacaat tattttgtaa gatgcttcta taaaatctat aaatggtttt attgtctcaa
    17041 aatgtttttt acttaatctc tttattgagg tagctataaa tgtagcaaat attattgtag
    17101 ctacaatatt tccatttgcc atagccatta caggattaga tggtagtaat cctcttaaag
    17161 tatccacaag agagtttatt tctttaagtt cttgattttc aactaaagta ggcatattag
    17221 ctcctacacc taacttcatt atatttgcaa cgataattcc aacaattgca gctatagcag
    17281 tagtagcaag aagcatacct aaagatttaa atgtcagagt tccaagattg ttatctttca
    17341 tatttataat tacttttata atggataaga aaactaaagg tactactaac atttttaata
    17401 agtccataaa tccagaacca aataggctat accacttact tacttcttgt agccaagtga
    17461 cttgagttgt atcattagga aaaccagcaa aagcttgtat tatgattccc aatatgagtc
    17521 ctagtactgt agcatatatt gttctcaatg aaaattttat ttttttcttt tcaaattgtc
    17581 taacaataaa gaacgtacct agaagtaata ttatgaaaaa aattgtttta aaatctgtaa
    17641 tcataagaaa ttgtgataaa aatgaacttt ccaatatttt tctcctttta tttaaaaata
    17701 aatttttcta agtttaaatg atatcaatat attaaaaaaa tgtcaatatt atatcacaat
    17761 ttacttaaat agagtaaaac aagttgattt tgaaaaatgt gattaagtac agaaaaatag
    17821 ggtataataa atgtttaaag aatttgaatt gtggtaagaa aataaaaaat agcttttata
    17881 agatttgatt tcaaattaaa atatgttaaa taaataacta aaaattatta taaaaaatgt
    17941 tttcatagaa tatatatcaa atgaaaagct taaaataagt gaagaaatta actagacatc
    18001 aaaggagaga taaaatgaga gtaataataa ttggtggtgt tgcagctggt atgagtgctg
    18061 cagcaaaatt aaaaagaata aaacctgagt atgaagttgt tgtttatgaa aaaactgaaa
    18121 tagtatcttt tggtgcttgt ggattaccat actttgttgg tggatttttt aatgatgctg
    18181 atgaattatt agcaagaaca ccagagaaac ttagagaagc tggaattgat ttaaatatat
    18241 ttagagaagt cgttgaggtt gatagtgaat ctaagaaaat aaaagtaaaa aacataaaaa
    18301 cagatgaaat atatgaagat tactatgata aattgatgat agcaactgga gcaagaagta
    18361 ttatgcctcc tataaaaaac ataaaattga agaatgtttc tacattaaaa agtttatatg
    18421 atggagaata tctaaaaaaa cttttaagta atgaagataa taaaagagtg acaataatag
    18481 gagctggttt tatagggtta gaagcagttg aggcatgtaa gaaattaggt aaagatgtag
    18541 atgtaattca gttagaagat agaatattgc cacaagtatt tgataaggaa atgacggatg
    18601 tattagaaga agaaataaat agacataatg ttaatttgca cttagatgaa atggttgtag
    18661 aactttgtgg agaagataaa gtagaaaaag ttataacaaa caaaggggaa atagatacag
    18721 atgtagtaat aattgctact ggcgtgagac ctaataccga gtttttgtca aatactaata
    18781 taaaaatgct aaaaaatgga gctatagtag ttgatgagta tggaagaact tctgtagaag
    18841 atatatactc tgctggagat tgtgcaacta taaagaatat agtaagtaat gaaaatgtat
    18901 atgttccttt agctactgga gctaataaat tgggtaggat agtaggagaa aacctagcag
    18961 gaagagaagt atcttatcaa ggttcactat cttcaagctg tataaaaatt atggatatgg
    19021 aggcagcatc aactggaatt acagaaaagc aagctaaaga tttaggcata aatgtcaaat
    19081 ctaaatttat ttctgattat aatcaaactc attattatcc aggaagaaat aaaatatatg
    19141 taaagcttat ttatgatgca gatacaaaag ttattttagg cggacaagtg gctgggttta
    19201 aggatgctgt ccaaagagca aatgtattgg cagctgctat ctttggaaaa atgaccacaa
    19261 atcaacttgg aatgttagat ttatgttatg ctccaccatt tgcaagaaca tgggatgttt
    19321 taaatgtagc tggaaatgta tctaaataat atttagatta tagctaatat agttgacaag
    19381 caattaaggg aatgaattta cctaaactat ttttatcatg gtaaaattca ttcctaaatt
    19441 tttattccaa atttttattc caaattttta gaaataagga ttccattaaa ttattcatca
    19501 aaatttaaac gcaagcttaa tctatcttct ccaaggatag tattttcaaa aacattagta
    19561 gcattttcta aatacatact aggtatgtct aaagaaggac taaaatgagt cagtaaaagt
    19621 tgtttgacat ttccaagttt tgcaagatta gcagcttctc taaaagtcat atgtttgttt
    19681 ctaacagctt ttgatatatc taaatcatca ccatacatgg cttcacatat aaataaatca
    19741 ctatctttta tgaaatctgg tattgattct ataggtcttg tatcggttgt aagacttatc
    19801 ttaactccct ttctcaattc tcctaagacc atatctggag tgtattgttt tgaatctaaa
    19861 actatatttt gaccttcttg gagtttgttc cataatattt taggaacttc gtttttagtt
    19921 gccttatcta tatcaaattt agggtttctt ctaaaattaa aactgtatcc taaacactct
    19981 atagagtgtt ctaaactgat tgttgaaatt tctaaatttc ttaaaacttt attatctaaa
    20041 gaaaaattgc cttgagggtt ttctataatt tttaaagtgt atggtacata ttctactaaa
    20101 tttctcatag aacgtataca atcgactatt ccaactggac caactatagt taaatcactt
    20161 gtacgaccac tatttccaat tgttgataaa agtcctaaaa gtccaaatat atggtcacca
    20221 tgtaaatggg ttatacaaat caagtctata tctttaaagc cacatttttt tagcttcata
    20281 gatacctgag taccttcacc acagtcaatt agtatttttc tacctttata gtttataaat
    20341 acagaggata gaaatctgtt tggcataggt acatttccac cacatccaag taaagttaaa
    20401 tctatcattt tttccccttt ctaaaattaa cacaaatctg ttgtttgttt ttattatgat
    20461 atcctattat aattatttta acattaaata taacaataaa tgtgtatttg agtcaagaaa
    20521 tattgtcaaa taaagttttt atatagaaat gtataaaaat ttggaaaaca aaaagtgaaa
    20581 attatattta ggagcattta aaggaggaaa atttaatgaa agtattaaag aaaattacta
    20641 ttttgtcatt aattacatta accttagttg gttgtagtaa cggagaagat aaaaaagtgg
    20701 ttgaaggttc taagaaaatt caaaattcta aaaaagatga acagcctata atagtacata
    20761 aagatgcaaa tatattgaaa gataggtatg agccaccaaa aggatttaaa agagttgatg
    20821 tagaaaaagg tagttttgaa tcatttctta ggaatactaa gctaaaaaat tatggagaga
    20881 aagtaaagta ttatgatgga agaactaagg aatcaaaagg tatttatgat agtgtatttg
    20941 atgttgatat tggcaataga gatttgcatc aatgtgcaga tgcaattatg cttatgagag
    21001 cagaatactt gtatcagaat aaactatatg atgaaataag ttttgatttt gttgatggtt
    21061 ttaaggcgaa gtattcaaaa tgggcacaag gatatagaat ttcagtaaaa gatagtggtt
    21121 caagctggta taaagcaact gaatattcaa catcttatga gagttttaga aagtttatgg
    21181 atatagtgtt tgcatattca ggaacgttat ctcttgaaaa agaattggag cctgtaaaag
    21241 ttgaggatat gaaaatagga gatgtgttta tagttggtgg aagtccagga catgcaagta
    21301 taattatgga tatggcagaa aatgaaaaga ctggtgaaaa ggtatttatg atagcccaaa
    21361 gctatatgcc tgcacaacaa acgcaacttc ttattaatcg taaaaatcca aatttgagtc
    21421 cttggtatag tttagatttt gaaggtgatt tgacaatacc tcaatggact tttaaaagag
    21481 accagttgaa aagattttaa aataataatt ttatataata aaagaaaaat atagatgtga
    21541 aaaaatgtaa ttagattaaa actaattgga tatggacaaa attaaattga tagataaata
    21601 ttaaaaatta cactaattaa tcttactata gtttaatatt tatctaaaaa gttttatgta
    21661 aaatataaat tttatattaa agctaaaact aatttgagga ggctaattta tattgaagat
    21721 tagaaggtat ttaattttgg taattataat tctaattaca acaagtcaga gttttatttc
    21781 ttatgggcta gagcgatttg aagaaataac catttttcac actaatgata tacatggaag
    21841 atatgctgaa ggtgatgacc atatacaaat aggaaatcta gccacattga aaaaagaaac
    21901 tccaaactca attttagtag atgcaggaga ttgtttgcat ggacttccaa tagtaaatat
    21961 ggatagaggg aaaagtgcaa ttgaattaat taaatgtgct ggatatgact atattactcc
    22021 tggaaatcat gactttaatt atggaaaaga tagactgttt gagttatcta aaagtgctaa
    22081 tttaggagag aatactttaa aatttttatc atcaaatatt tttgaaaatg gaaaaaaagt
    22141 ttttgatagt aatgatataa aagaaataga tggaataaaa ataggatttt ttggactctc
    22201 aacccaggaa acaaagagca aaactggatt taaaaatgtg gaaggattag agtttaaaaa
    22261 tcctatagaa agtgcaacag aacaagtaaa tgaattaaaa ggaaagggtg ccaatgtaat
    22321 agttgcaata tgtcatattg gtacaaatag tttaagtaag ccaaatagta tagatatagc
    22381 aaatgaggtt caaggaattg atttgattat tgatggacac agccacacta agtttgaaaa
    22441 tggtaaacaa gtgggtgata cattgattgt aagtgcagga caatatttag aaaatattgg
    22501 cgagataaaa ctaactttgg atactaatga tgtagaaaat ataaaaatag aaaataaatc
    22561 agttagatta attggaaaag aagaagcatt aaagtataag cttgactccg ctgtaagtaa
    22621 aaaggttgat gaaataaaag aacaacaaga aaaaatatta gataaagtta taggggtaac
    22681 tacaaatact ctagatggtt catatgaaaa tgtaaggaca aaagaaacta atttgggtaa
    22741 tttaataagt gacattttac tagataaaac taaggctgat atttctttat ttaatggagg
    22801 gaatattcga gatacgatag aaaaaggcaa tataacaaga agagatattg tagatgtatt
    22861 tccttttagc aatactatag ttaccaaaga acttacagga gcacagatta aagatgtatt
    22921 ggagcatgga gtaaaacttt atccagaaaa aagttcagcc tttttgcaag tgggaggaat
    22981 ttcatattac tttaatccta aacaaaaaga aggcgaaaaa ataacaaata ttcaaaaaga
    23041 aggaaagcca ttagatttaa ataaaaagta tgtagttgca acgaatgatt atatagcatc
    23101 aggtggagat gaatttcctt gtttttcaaa agagccagta ctaaaggaat ttggaaattt
    23161 agagagtgca gtcattgaat atatagagta caaaaaagaa atatcaaaaa atgtagatgg
    23221 aagaattggt attaaatcta aagatgagtt aataagcaag aatcatgaga gtgatttgat
    23281 attaagtgaa aatgaaaaaa atatcaatga taatgaagag aatctatcta ataatataaa
    23341 aagctctgat agtgataaaa ataaaagctt agataaaaca agtgctagag aaagttctaa
    23401 tctaggaata tctaaaagag aagctaaaga aaaatctcct aaaacaggag atttaggttt
    23461 ttcaaatagt ataattatat ttatagtttc aagtacattg atatgtttat tgaattttaa
    23521 tcaaaaagag ttaaaggata aaaagtcaaa ataaaaatta atgagcaaaa attagtagat
    23581 agtaatttaa ttttagataa tagtaaacag caaaggaaat tagttatata aatactaatt
    23641 tcctttgttt tatgttttaa catgattact tttaaataaa attgtatttt atgaaaaata
    23701 attacactaa atggcatagt attatgggga tttttagttt ttattcaagt aaatgaaatc
    23761 atattaacaa cttctgatat atttacaaat tgataaaaaa atgattttat tagtatgata
    23821 taatttagct agtatatatg atgatggagg atatagggat gaataatata ttacttttgg
    23881 aagatgacaa atctttaaat agaggaatta gttttaaatt aaaaaaagaa ggatacaatg
    23941 tttttagtgc atttggtata gaagaagcaa aaaatatttt cgcaaaagaa gagatatgct
    24001 taattatttc cgatataggt ctacctgatg gtagtggttt tgacttttgt gaggagatta
    24061 gaaagaaaag tgatgtttac ataataatgt tgacagctct tgatgaagag gtggatattg
    24121 tcacaggata tgatttaggt gcagatgatt atatcacaaa gccttttagc ttgatggtat
    24181 taatatcaaa agtgaatgcg cttatgaaaa gagtaaatac agtaaaaaat tatactctat
    24241 tagtttgtga tgatttattc ttttattata tagaaaataa attaattata agaacagatg
    24301 ataaggaaga agagataatt ttaagtaaga cagagacaaa actattaaaa tatttgatgg
    24361 aaaattctat gcagacattg actaaagagc aactgttaga atctttatgg gatagtagtg
    24421 gtaattttgt agatgataat acgattgcag taaatataag aagacttaga caaaaggttg
    24481 aaaaaaatcc atctgaacct aaatatataa aaacagtaag aggggttgga tatatgtggg
    24541 gagaaaggag tataaaaaaa tgctaaaaaa tatgaacctc aaagatggtt taagtgtgaa
    24601 agatgattat ataatgagaa gagttattgt atattctgtt ttatctgtac taatagtaac
    24661 ccttgtattt atactttttg aatatagcag attacataaa ttgtatgaac atcaaataaa
    24721 aaacactcaa aatattgctg gaatattgat tgaaaaatat cctaatgatg aaatagatat
    24781 agtaaattct atttataatt ctgattatag taaggtgtct actggagaaa aggcatttaa
    24841 gaaatttggc tatggattgg aaaataaaat gtcaaatgat aaaaatttta gcttatactt
    24901 aaaatctttt tttaaggaat cattttttat ttttttaatg atgtttatag tagttatagg
    24961 tataatatat tattttataa gatacataaa taaaagattg agtaaaattt attttatagt
    25021 agataagatg tcacaagaaa actacttgaa ggacactact gagtcagaag aaactggtta
    25081 tctagtagaa tataatgaat actttaaaga aggcatattt agtaagataa ataactgtct
    25141 atatgagctt aatagaagtt taaagataaa gtttattaaa ttagaaaaag aaaaagaaag
    25201 tgtaaaatca ttagtaacag atatttccca tcaattaaaa actcctttag catccttaaa
    25261 attatacaat acattactta tagaagaaga attagaagaa gatgaagcca acgagttctt
    25321 attaaccaat aaggcttcta taaataaatt agaaaattta ataaattctt tagtgaacat
    25381 atcaaggtta gaaattagca tgataaacat aaaaaaagaa gataatgata taaaaaatac
    25441 tattctaaat gcagtaaaaa gtgttacccc taaggctaag agcaaaagta taacattaaa
    25501 tttaaatgaa tttaacagta gaattatacc acatgataaa aagtggactg aggagagtat
    25561 ttttaatgta ttagacaatg ctgtaaagta tacacaggta aatggagaaa taaatatatc
    25621 tgtagaagaa actgctaatt tctttaaaat tataatagag gataatggca tagggattga
    25681 aaaaaatgag tttaataata tatttaaacg tttttataga ggttctgctg atgaaattga
    25741 atctgtagaa ggtagtgggg taggattgta tttaagtaga aagattttag aagaacaagg
    25801 tggaaatatt atagtttctt caaaagtagg aatagggagc aagttttctt tgtttcttac
    25861 aactatgtaa tattaaatga aaggaaaatg taagcctcta catttattat ataagtataa
    25921 acagctccag aaataaaaaa ttaataaaat atggagtaat ataacttaga atgagaggat
    25981 aattttatga aaatactata tactgaaaat ttatcaaagc attatggaaa aggagaaagc
    26041 ttagtaagag ctttggacaa tgttgactta gaaataaatg aaggtgaatt tgttgcaata
    26101 ataggaaaat caggttctgg aaaaagtaca cttttgcata tgattggagg tcttgatata
    26161 cctacatctg ggaaggtgta tatagataat aaaaatatat ttacattaaa agaagaagaa
    26221 cttgctgtat ttagaagaag aaaaataggg tttatatttc aaagctataa tttaattcca
    26281 tctcttaatg tatgggaaaa tgtagtgttg ccaatcggtt tagatggtag agaagtagat
    26341 gaatctttta taaaagaact tttaaaatca ttaggacttg aaaataaaca cgacgtttta
    26401 ccaaatacat tatcaggtgg tcaacaacaa agggtggcaa tagcaagagc attagctaca
    26461 agaccagcta taatacttgc tgatgaacca actggaaacc tagattctaa aacgtctgat
    26521 gaggttatga gtatattaaa atctatgtct aagaagtaca gtcaaactct agttatgata
    26581 actcatgatg acagtatagc ccaaatggct gatagagtta tattcataga agatggcagg
    26641 gtgtcaaagg ttggtgataa aaatgattaa tactactaaa atagcaaaaa gtaatttaaa
    26701 gcaaaataaa tcaaaaagta ttctaataat aattactata atactttcaa ccttaatgct
    26761 ttcttctatt ggaatttata ttgttgatgc aggagcatat caaaaagaaa atactataaa
    26821 gtattcaggc aattatcaag gtatattagc aaatgtagat gaaaaacagg ctgatatatt
    26881 gagtaatcat gcagatgttg aattaactgg tgaaatgaat ggagtaggtg ttgaaaaact
    26941 ggaagatgat tcaaatattt ctctagcata catgaatgaa gatgctttga aattaaatag
    27001 ttttgaattt atcaaaggaa aattgccatc aaaagagaat gaaattgtgt tagatagtgg
    27061 agctttaaag gcacttggtt ataaaaataa agatttaggt gaaaagataa aaatatctta
    27121 tgatgactat aaaaatgata aaaaaattga aaaagagttc attataagtg gaatcttaaa
    27181 aactagcgaa atatctgaag caggtaaata ttattatgct attatatcag aatcatatat
    27241 gagaaatact agagatatgt cacaagaaga ttttaatatt tatgtgaaat ttaatgataa
    27301 aagtaattta tcaatagagc aagcaaaaga aaaattagat aaaattgcta atgatatagg
    27361 actggatact attaatactg ctgtaaatga aaattatata aatgctttaa aaccagatat
    27421 ggaaacgatt atgggtggag tttttgtagg gttagtaatt gtattatcta gtattttagt
    27481 aatatacaat atattttata tttcaatagt tacaaaggtt caagaatttg gaaaacttag
    27541 agcaattggt gcaactaaga aacaaataaa aaatatagtg tttaaagaag ggttcatatt
    27601 agccggaata gctataccaa taggaataat tttaggctat gtacttgcaa atattataat
    27661 aaaatcattt atggatatag atgtaaaatc atcacgatta ccagttatat tatcggttgt
    27721 ggtaataagc tttatatctg ttgttttatc acttttaaaa ccaatgaaag tagcatcaaa
    27781 agtatccatt gttgacgcag taagatatac aggaaataaa ataagtaata agagtaagag
    27841 aaaaggatat aaaaatataa atctaaagag attatcacat gccaatttag aaagaaataa
    27901 aaaacgtact tacatgacat tggcatcact tatacttagt ggaactatat ttataacagt
    27961 atcaactgcc ttagaaagtt ttgatgctga gaaaatggca agagaacact ttccttatga
    28021 tatagaagtt agactatctg gttatgaaat gaacagtgat aaaaatccta aagataattt
    28081 gaatatttta caaatggata atcctctaag taaagatttt tttaatcaaa taaagaacat
    28141 ggaaggaatt aaaagaatag aatctgcaag aagtgtaaaa attggtatgg aggactatga
    28201 tgttgaattt aagtatgacc ttttacaaag tataaatgaa aatgatgtaa aatcattaaa
    28261 caagaatata atagatggaa aaataaatct tgaaagactt caaactggag atgaaatagt
    28321 aattactcat gttgatacag caaaagaaat gggagtaaaa gcaggagata aaataagatt
    28381 aactttatat gatggagata aaaagataaa aaaagaattt aaagttcaag caatagctat
    28441 gggggttcca agttttggta tagggaaaga ttttatagat agaactttga aatacgattc
    28501 aactagtagc ttgggaatat atacagaaga aggaaagtat caagaaatca aagatagtat
    28561 caagaagatt gctaaaaata atggattttt agagactgat tttatagata gtagaattga
    28621 gtcaaataag gctactattt catttataaa gataatggga tacacgctaa caggcataat
    28681 aggtgtgatt ggatttatga atcttgtcaa cacaatgata actagcatag ttactagaaa
    28741 aaaagaactt ggtatgcttc aagctattgg tcttactaat aaacaattag tgaaaatgct
    28801 taattcagag gcaatatatt acacttctgg aatgatgata ggaagtattc tatttggagg
    28861 tatattaggg tatattgctg ttatatttct aaaaaagact ggattatctt atgcaacata
    28921 ttctttgcca atagtaccaa tcttgttgat gattgtgtgt attcttatag ctcaatttat
    28981 aacaacttat ttgataggac gaagttttaa taaagaatct cttattgata gagtaagata
    29041 cagtgaataa aatgcaaata tttatggtta gtttaactag caaaaaacat ataaaaaaat
    29101 atagttaaag agattcataa ttaaataggt taaagcatag tacagagcaa acaatttaaa
    29161 cagatgtttg ctctgtattt tattatgtaa tcaataatat atctaatata ctgatattat
    29221 tcatgttaga aaatgtaccg gtacaattct aaaaaagtat aaaattgtac catataaaat
    29281 gaaaattttg tataataatc gtatagaaaa taaataggag ctgatatata tgaataagaa
    29341 gattaattat gcaccaggac caactgaaac tagggaaaat gtaagattag caagagcaga
    29401 aaaaacaaca aatccagata tagatattga ttttgttgaa ttttataaaa agacatgcga
    29461 gaagtttggt aatataattg gaacaaaaaa cgatgtttac atattgagtg gtgaaggaat
    29521 attaggtctt gaagcagcat gtgcatcact tacagaaaaa ggagatagag tacttgtaat
    29581 tgacaatggt atatatggag aaggttttaa agattttgta acaatgtatg gtggggagta
    29641 tgtgcttttt tcaagtgagt atactaaaag tatagatatt gatgaattga aagcattttt
    29701 agatgaggat agtaatttta aatatgcaac agtagtgcat tgtgatactc caactggcgt
    29761 attaaatgat gtaagcaaaa tatgtccatt acttaaaaaa tatggaatat taactgtagt
    29821 tgattctgta gcaggtatgg taggagaaag attaagtgta gatgaatcta aaatagatat
    29881 aatattaggt ggttcacaaa aagctatttc tgcaccagca ggacttacta tagtcggaat
    29941 aagtcaagat gcaaaaaatt gtataaaaaa tagaaaaact gatgtaatag gtttttattg
    30001 taatttaaat atatgggaag gctattatga gaaaaaatac ttcccttata caatgccaat
    30061 aagtgacata atggggcttg ataaagcact tgataatata ttagaagaag gaatagaaaa
    30121 tgtattaaat agacatgaaa agatagctta tagtgttaga aaatctattg aggaatatgg
    30181 tctagaacta tttttagaag aaggatattc taatacagtc acagctataa aaattcctga
    30241 aagtatagga gctttagaac ttactgatta tatgcttaaa aattataata cacttgttgc
    30301 aacatcacta aatcaatata tggatactat tttaagaata ggtcatatgg gagagaatgc
    30361 aaatctaaat aaaatagaac atgtactaaa tgttttggat aaaagtttaa gtgcattagg
    30421 attcaaagga aatggaaatt tgttaaattt atttaataag tattattttt aatagatagg
    30481 gggatatagt atggaagtta cagctaagca aaaatttaca acgaaagaca tggtggaaac
    30541 ctcactatta atagcattag tatttattgc aactaaattt ataaacataa gattaccaat
    30601 atctataaat ggtgggcttg tgcatttagg aactgcaatg ttgttcatat cagcaatagt
    30661 atttggaggt aaaaaaggtg ctttatcagg ggctattggt atgtcacttt ttgatttgat
    30721 atctgggtgg actttatggg caccgtttac ctttatagtt agaggagtta tgggttattt
    30781 acttggaaag attgcatggg caaatggtaa taatgggaat aattttttaa tcaatgtaat
    30841 aggaatatgt gtttcatcaa tttggatgct atttggatat tatgtaacag aagttatact
    30901 ttatggtaat tttatagtac ctcttacttc aataccaggt aatttaatgc aagtattgat
    30961 aggtcttata atagcgcttc ctatttctaa ggtattgaaa aaatgtataa aataaatata
    31021 aagtgaacta aaatttatga tagcataaat tatactgtat aatattagga tggagtacat
    31081 aattaaaaaa ttttagtata gaggttagtt cacaatgtta tcagttacaa gatattcaat
    31141 caaaaatgtt cgtttaaagc cgtgggtaaa gtttatttgg tattttgaga caaaatcaaa
    31201 tatactgtta aataataagt tacttccgac agacagtata gatattattc tcaatctttc
    31261 tgatgttatg gaatataaaa ttgaaaatca agactatact gctagtaata tgcattttaa
    31321 tggaataagg gataaacatg gatttattat tcaacatgga aatatacgtg ttatagggat
    31381 ttctttttat ccatttggtc tctatccatt tttaaagata ccaatttcag agtttaacag
    31441 acaaattgtt gacctagaag cagtatcaca gctatttgca aaaaaattgg aagagtcatt
    31501 aaatccaaca caatcagtag aaaaaattgt tttatattta gaagaagtat tattatccat
    31561 attagaagaa gatttaattt caaataaata tgtaaagctt ctaaattcat ttatatatgt
    31621 taatagatat agcaatataa aagcattttg tgatgataca aatataaata ttaaaacatt
    31681 ggaaagaatc tgtttaaaat atacagggta tacacctaag attttaaaga gaatttacag
    31741 atttaaaatg gcaagcaatc aacttattta taattataaa gatgatgaac tttttgattt
    31801 tatttatgaa aatgagtact atgaccaagc acactttata aaagaattta aaaaattttc
    31861 agggacgtca ccaattaaat ttattggtga gaataagacg attaaagaaa atataaagta
    31921 cagctattta taattatact gtcgattttt tacaatacct ccaatttatt ttttgatatg
    31981 atataggaaa ataaattgga ggttttacat atgaaaatta ttacagaaat agttgagttt
    32041 aatgtggaag aaaatttatc aaaagaagag tttatagaaa ttgtaaatga cttagaatta
    32101 aaatttcatt ctattcaatc tggttttatt gatactgagc ttttatatga tgaaaagtct
    32161 caaaagtgga ttatgataca acattgggaa tctatagaag acctcaagag tgcttctagt
    32221 aaaatgttta aagattcttc aactgagaaa tttagaaaag ctttaaagaa tcaaactgtt
    32281 aagatgaata taataccaca aattaaaagt tggaaattat agaacttaat gtaaaagata
    32341 gttaaatagt atcaaactaa attagccaaa taacattttg tatttaaatt gttatttggc
    32401 ttttagtgtt tattttaata tgagtgttat atactagaaa aaccaacctt aaatactact
    32461 atctaaaagc actattgctg tacgagaggc aataggcatt ttagaagaag gaggagttga
    32521 gctaaagtat acatcataat ctcttaagtt ttcttttttt gtgtttcctc caaactctac
    32581 catatcagta tttaatatcg ttttgtagtt tgtattttga aactttgaaa tatcaactga
    32641 ttgtattaga ttagggtgga aattaaatat aaataaatat ttgcccttac tgtacaccaa
    32701 aatcttttta tcattatcca tatgtataag ttcatgacta ttttggataa aaatatcact
    32761 gtattttgta agttcgagca tagatttatc aaaatttaat aattgtttat actttaagtt
    32821 gttatcttct gaaaggctcc attgtcttct ggcatactta tagctccaat tgttgccttc
    32881 tcgtggaaaa tcaatccact caggatgtcc aaattcattt cccataaaat ttagatatcc
    32941 ttcacctgct agagaaaaag ttattaattt aattaattta ataagagata ttgctctatt
    33001 gataacatgg ttatttgagt ttatttccat attccagtac atttccttgt cagctagcca
    33061 aaaaataatt gttttatcgc caactaatgc ttggtcatgg gattcacaat atcctatatt
    33121 tttttctcca ggtcgtctag tagtaagttc ataccacatt tttcccaaat cccagtcttc
    33181 atcagataag ttagagatag tttttatcca aaaatcaggt actcccattg cgagtctata
    33241 gtcaaatcca attccgccgt cttttatagg gatacacata ccaggcattc cactcatatc
    33301 ttctgcaata cttatcgaat taggtttaat ttcttttatt aattcatttg caaattggag
    33361 atatgttata gcttcaatat ctgtattcat actaaaatat ttttcataac tatcaaatga
    33421 aactccaaga ccatggttat gatataacat tgaagtcaca ccatcaaacc taaagccatc
    33481 aaaatggtac tcatttaacc aaaattttat atttgaaagc aaaaaatgta ttacttcagg
    33541 tttaccatag ttaaaaagtt ttgtacccca agcaggatga tttccctttg aacctgagtg
    33601 gaaaaattga tgttcacttc catcaaactc atttattcct tctaaagtat tctttacagc
    33661 atgagaatga actaaatcca ataaaacagc aatccccatt gaatgagcag tgtttatgag
    33721 gttttttaag tcttcaggag taccaaacct agatgagatt gcataaaagt ttgaaacttg
    33781 gtatccaaaa gatgcataat atggatgttc cataatagcc ataagctgaa tggtattgta
    33841 tccagctttt tttatcttag gaagtatttt ttcagtaaat tcattataag ttccaataga
    33901 ttcgctttca gtagacatac ctatatgaca ttcatagatt agtggataag ttatgttttt
    33961 taagtcaaaa tcattgtcag tccagataaa tggagttttt ggttgccata tttgtccatt
    34021 aaatccacca aaatcttttt gaattactct ttttatatat aatggtatac ggtcaaatgt
    34081 ttttccattt gcagtaactt gtacctttac ctctgatttg tgaggtaagc tattttgacc
    34141 aggaataaat atttcccaat taccagaccc aatttttctt agaggatgag attttctatt
    34201 ccaattatta aagtcaccaa ttagtgacaa actatctgca tttggagccc attccctata
    34261 gaagaatcca tcatttgtct gatgaaatcc atagtaaaga tgagcatttg caaaagaact
    34321 aaaatcttta tagtttttca atgtttttga tttcatattc tcataatgtt tcattcgctt
    34381 ttttatatca gattcaaatg gttgtaggta tacatcaata tctaaaattt taaatctttt
    34441 ttgacttttc attgtatttc tcctccataa taaatattac atctaaaaaa taatatttat
    34501 ctcatactat cttctctata taattgatat atattatata atcctaataa aaagcttaag
    34561 ccaccaatga ttaatttcat aatttacctc cctagtattt atacttatat atcgtattca
    34621 tcaaaattta aaagtttgtt taaaactctt ttaataatat cataatcaaa gcctttatag
    34681 gaaagatgtt gagaaatttt ttgatatatt ttctttttat cttctttctt tactctttca
    34741 tacctttttt ttgctagata catagcattt tcaaattcag tgtccttgtc taattcagat
    34801 actgcttcat tgattgtact tctattgata cctttattat ataaattctg cttaattctg
    34861 tttttgccac atttatttag gttaacattt gtgttaacaa ttttttgagc taatacactg
    34921 tcatttacga gattataact tttaagaaaa tctatgaccc tctcaattat attttcatca
    34981 aattctgatg atagtttttc ttttaatttt ttttcagatt ggtcagcatg agataaaata
    35041 tttaatgctt tatttttagc ttttatatac atttcatcat ctaaaatagg ttttaattct
    35101 tcttcattta tttcattccc cttttttaaa ttaaatgtat aaacaagttc tttaaatata
    35161 gcaataaaaa atttatcatc tacataaata ttaactctat catcatttct tttttgttgt
    35221 tctatttttg taattatacc cataagtcct ccttttttat atgtaattat attaacaaaa
    35281 gcaactaata aaatttaaca aaaaacttat atttgtatgt tatattttat caaaattaag
    35341 acaaaatagt aaaaagttat ttttattaaa aagtaaagta gaatcatgtt aaataattat
    35401 ttttttaagt gttttttagc atataaatat aattatatac ccaaaaaaac aaattataag
    35461 ctttaagaaa taaaaaataa tggtacaata gtattataac attaaaagga gacaaaatat
    35521 gagaagtgaa aatctagtta agatggcaga gttgaaaaat actgaaaaac tagagaaatt
    35581 taatcgccat aaaggcaaaa tcaaaatagg tatattggga ggtacttttg accctataca
    35641 ctatgctcat ttagcaacag cagaatttat tagagacaag tatgacattg acaaaataat
    35701 ctttatacca tcaggaaatc caccacataa attatgtatc actacagata agtatgatag
    35761 atataatatg acacttctag caactgaaag caacgaagat tttttagttt caaaagtaga
    35821 aatcgaaaga aagaaaagga cttatacaat agatacatta aaatacttaa agaaaaaata
    35881 caaaaatgca gacatttatt ttataacagg tgcagatgca atttgtagtg ttgaagagtg
    35941 gaaagatgta aagaaaaact ttgagttagc tacttttata gccgcaacta gaccaggaat
    36001 tagtttgtta aggtcacaag agactataga aaaactaact aagaagtata atgctgacat
    36061 tataacagtt tatgttccat cactggatat atcgtccaca tatataaggg aacagctaaa
    36121 tgaaggcaag tcaatacgtt acttagtacc cgaaaatgta gaaaattatt tatatgaaaa
    36181 taaactatat caatatggag atgattaaat gaacttagaa aatattaacc aaagactaaa
    36241 tcaaatgcta ccagtgggga ggcttagcca ttcaaaaaat gttgcaaaat gtgctgaaaa
    36301 attatgtgag atttatggat gtgacaaaga aaaagcttac ttagcaggaa tgattcatga
    36361 ttgtgcaaag tatttaagtg acaaggaaat agaggattat gtaaataagt atgaaatata
    36421 tttagaccca atagaggatg gaaatcgttc cttgtctcat agcgtaattg gggcgtacat
    36481 atgcgagtat gaatttgaag tagaagatga agatattata aatgcaatca aatatcatac
    36541 aacagggaga gaggacatgt ctcttttaga aaaaataatt tacatagctg atttaattga
    36601 agaaggaaga aaattcccag ttgtagatac attaagagaa ttagcatatg gagggaagct
    36661 tgatgaagca cttttaactt cttttaataa tactttaatg tttgtcatca ataaaaaaga
    36721 agagatacat ccaagaacag ttatggcaag aaactatcta attaaagaaa agttattata
    36781 aaaaagctat ataaaggcaa acatattaat aaatttaaat ttgactatgt tacaaaatcg
    36841 tattaatatg ttacaataac taagtgtatt ttaattagga aagtgaggaa tttttatatg
    36901 acagtggaac aaatgacaaa aatagcatat gatgccatag aagataaact aggtcaagat
    36961 acagttataa taaatatagg aaaagtttct agtttgtgtg attattttat tattactaca
    37021 gcatcttctc agagacaggt aaaagctatt gctgacaatg tggaagatga attagcaaaa
    37081 ctaggattag agccaagagg taaagaagga caaggaactc aaacttgggt actccttgat
    37141 tatggagaca taatggttca tgtatttaat gaggaaaata gagggtttta taatttagaa
    37201 aaattatgga aagatgcacc ttatatagat attgacacat tagcataaac atgataatat
    37261 atgttattat aattagaaaa tttcaaaaat tatattaaat tgaatagact agagcagtaa
    37321 aagattatat tttttcagag agttagtgga aggtgagaac taatattata taactttgaa
    37381 cttactagat taaaatctat tctccatggc tggattaaaa gctatctaag agagtctata
    37441 tatgtagtag gctaattagg gtggtaccgc gaagatttat cctcgtccct aaacgtaagt
    37501 ttagtgacga ggatttttta ttttcaaaga attatttgga aattataagt aaataatact
    37561 aaataaggta gttatacaca attaaaaata ggaggcaaaa tatgagcgta tataatttta
    37621 aagaagtaga atcgaaatgg caaaaaatct ggaaagataa taatcagtat aaaatggata
    37681 ctgcacaaac tgaaaaacct aattattaca cattagaaat gttcccttat ccatctggaa
    37741 aaatacacat gggacatgtt agaaattatt ctataggtga tgttgtcgca agattcaaaa
    37801 aaatggaagg atataatgta cttcatccaa tgggatggga ttcttttgga ttaccagctg
    37861 aaaatgcagc tataaaacat ggaatacatc cgcataaatg gacaatggaa aatatagaag
    37921 aaatgaaaga gcaattaaat ttattaggga ttagttatga ttgggataaa gaagttgcaa
    37981 cttcaactcc agaatactat agatttacac aagaaatatt tttgaagttt ttagagcatg
    38041 ggcttgcata taagaaaaaa tcatatgtta actggtgtcc ttcttgtgag actgttcttg
    38101 caaatgagca agttgttcaa ggagcatgtg agagatgtaa agcaacagta ttaaagaaag
    38161 atttagaaca atggtatttt aagactactg agtttgcaga agaattactt aatgacttag
    38221 atacattaga tggatggcca gaaaaagtta aaacaatgca aaaaaattgg ataggtaaaa
    38281 gtacaggagc agatttagtt tttgatatag atggaactga taaatctatg acagtattta
    38341 caactagacc agacacaact tatggagtta cttatatggt acttgctcca gagcatgaat
    38401 tagttaaaga attggttgca gggactgaat atgaagcaga tgttgaagct tttgttcaaa
    38461 aaatgcatac tatgacagaa atagaaagaa cagcagctga tgtagaaaaa gaaggaatgt
    38521 ttataggtag atatgttata aaccctttaa atggcaagaa agttcctcta tggatagcta
    38581 actatgtatt agttgagtat ggaacgggtg ctataatggc agttccagca catgatgaaa
    38641 gagatagaga ttttgctgaa aaatataatt tagacataat tgatgtaata acagaagata
    38701 acaaaatgat aaattcagaa gaatttaatg gattagatgc ttcagaagga tttgaaggaa
    38761 taatcgataa gttagaaaaa gaaggtagag gaaagagaac aattaattat agacttagag
    38821 actggttagt ttcaagacaa agatactggg gttgtcctat acctgtggtt tattgtgatg
    38881 aatgtggaat agttccagtt aaaaaggaag atttaccagt tcttttacca acagatgttg
    38941 aatttactgg aaaaggggaa tctccactta cgacttcaaa gcaatttatg tcaacaactt
    39001 gtcctcactg tggaaaacca gctagaaggg aagttgatac tatggataca tttgttgatt
    39061 cttcttggta tttcttaaga tatgtggata gcaataatga aaatgaacca tttagtaagg
    39121 aattagttaa tagatggcat ccagtagacc aatatatagg tggagtagaa catgctataa
    39181 tgcatttact ttatgcaaga tggtttgtaa aggcatttaa gagtatggga atggtagact
    39241 tcaatgagcc atttaaaaac ttacttactc aaggaatggt acttatggat ggttctaaaa
    39301 tgagtaagtc taaagggaat acagtatctc ctatggatat aatagatgag tatggagcag
    39361 atactgcaag acttttcgta ttatttgcag caccaccaga aagagatttg gactggtcag
    39421 agcaaggtgt tgatggatgc tttagattct taaatagggt ttatagattg gttgacgagt
    39481 tagcagatgt ggttaaaaag gatgtagagt ttggagaatt aaattcccaa gataaggata
    39541 tgagatatac tatacactct acacttaaaa aagttactgc tgatttaagt gaaaaattcg
    39601 gatttaatac tgctatatca gctcttatgg aattaataaa tgatatgtat aaatataaag
    39661 agttagataa tataaacgaa gcagttataa aagaaggtgt acaaactata gtaactataa
    39721 ttgcaccatt tgcccctcat ttaggtgaag aactatggac tatgataggt aaagaaggaa
    39781 gtgtatttga tatagactgg cctaaatatg acgaaaaagc tttagtaaaa gatgaaatag
    39841 aagttgttgt acaagttaat ggaaaagtta gaggaaaatt aactgttaac tcaaatatat
    39901 ctaaagatga gatggaaaag gtagctttag aagatgaaaa aataaaagga ttagttgaag
    39961 gtaaaactat agttaaagtt gtagctgtac ctaaaaaatt agtaaatata gttgttaaat
    40021 aactcaaaaa tatgaacaaa aatataaatt tataaaataa atgaggctgt ctcaaaatag
    40081 agataagcct tttttcattg ttgaaattat aaaaatagat ttgattttat acaaaaaaat
    40141 gattaaagaa ctaaaaagtt cattcttata taccctagtt gttgttttaa atattattat
    40201 aattaatgtt aaatcgagtt aatgtattaa gtggtatgta aatcattcag tttccaaagt
    40261 gttgttcgtc aaggaactgc tctaagctta aacgaaaaaa atataattat tgtattttga
    40321 aatttttttc tatataatga aaacaggcaa aaaaggtgca tatctatgct ttatatgaaa
    40381 cacccagaca acgaaattca gattcatata atagctacca tgtttctaaa aaggaacttg
    40441 taaaaaagat agcgtttcaa cttcccagtt gattaaaatt atcagcagga aaacaagtat
    40501 ggtcagcagt ggtattctaa tgggtgttgt cgatatatcc aagttgggat tgtctgagga
    40561 tgttatcaaa taacttgtga taggtgcagt agatgtggag attcctgata cggatttatt
    40621 ctcaggggat ggttgcttcg ggagatatgg agcgtaacca gtttattgat atggtaacca
    40681 ttttttgtct aatttgatga aagaatccca agaataccat acagaagtaa gacaggaatt
    40741 aactggtggt ataaactgat aaaggcaaat ttaaaaattt tgataggatg attttaagat
    40801 ttatcttcta ttttgttttt tagaaataat tgaaatgtta tgaggaggta tgtacaaatg
    40861 gagactgtaa caaataatca atcaggtgta gaaattcaac tcagtctgtt tgaagctatc
    40921 aaagatttat tgttaattaa tcctattttc ttgttgggaa ttatcttgat tggtattttc
    40981 ttagttgtaa tattcaagaa aaatagtgat attccaaagg tcaaaacatc tattttatca
    41041 ctggcaatgt attactactt atgtttaaca ctatcgcata ttgttggtat acctacattc
    41101 ggtgaatata taagactgtc acagttaggg gaaacgttct ttaatccaaa cataaatctt
    41161 attcctttta gtgatggatt tagtttgagt tttattttga atattttact ttttgtccca
    41221 ttaggttttt tatgtccgct tataagcaaa acctttgaac gtttgagaaa tacattcttg
    41281 attggttttg gattatctct ttttatcgaa actattcagc tttttacgtt acacagagca
    41341 accgatatag acgacttact cacgaacgta attggaacaa taataggcta tttctgcttc
    41401 aaactgattg ctaaattgcg aattgtaaaa ctacattcag atgatgactc tatggaacag
    41461 gattacacag tatgtattcc gattgccatt ataatagttg cccttatatt aggatttttt
    41521 agttaagttc caaatagcta atttgggaat ccagacaata taacagatac tatgttacct
    41581 tttacaggag catactatct gttatattgt caacatccta ttttatggtt tgtgtgtagt
    41641 ttcctgtaaa ctgaactaaa taattaaata gaagctatta gaattaataa taacagatag
    41701 atattaataa gcataaacaa atagtaaaat gtgtagatat agacgttttt aagtgaaact
    41761 attataaaat aattgactga taatcaactg acaaaaccta tttttttagg tttaactgac
    41821 atttaactga cagtcagttt ttactattta aatagaagtt cgcttagatt gtcggaagct
    41881 tctttgtcca tttctttaag tacatgagaa tatctattca tagttatttt tatatctgta
    41941 tgacccaatc tttcagaaac aactttcata ttagttcccc ctaaaagcag cagagtggca
    42001 cttgtatatc ttaaatcatg tattctaatc ttttttaaat tatttttttt gtaaaattgt
    42061 gaaacgtttt tcttagtgaa gaaggtagaa acggatttaa attggtgttt agacaaacta
    42121 agttatttct gttttccagg ataccttaca attttaattt gctttgtctt agtttttcaa
    42181 ttttcaattt ttcaattaat tcttttggag ctgataaagc tctttttgat tttggtgttt
    42241 ttggctcttt aaaagatatt ttgccattag aatagacaag aatttgatta acatttatca
    42301 gattgttatc taagtcaaca tctgaccacc taagcccaat agcttctcac attcttaaac
    42361 ctagaagtaa cattaaaaga ataggtattt ctatattatt accaagtaac ttttctatta
    42421 gcaataatac ttcttctcta ttgtatattt catttgtaga atatttttct ttagaaggaa
    42481 gttttataaa atcacatgaa ttttcttgta tttctcttaa tctatacgct tcccttatta
    42541 cagaacttag aaagctatac cttactttag cactagtaaa ggtagaatta ttaaagttat
    42601 aatttacaaa agcttgtact gaactaggat ttacttctgt gagttttaga ttcttaaaaa
    42661 aggttctatg taatttttaa cccaagattt tgtatttgta acagtatatg gagaccaatt
    42721 atttttattc atgtctatat atttataaca tctttctaca aatgtcatac cttttggagc
    42781 aacaaactta ttattattta tagtagactt tatttcaatt aaatgttttt cagcatcctt
    42841 tttcttttta tagcttccat aacttttttg tttctttttg ccagtttctt attccacata
    42901 tacatagaat ttttcccatc tttttcttat aaaagctgat ttgatattca tatatgtacg
    42961 ctccctttat aagttagttt tataaaagaa cagttggact gctctaatta tgtcattatc
    43021 tttttaattc tttacagtta cattataaca cgtatttgta tacacttaaa ttaacaggaa
    43081 gataaatatc gttaaaggag gaaaagaaaa tttaatgtag aattatgtaa gatatatagt
    43141 atttcatata taaaaggggg agatattgtg aaattaaaga aattattatc actagggtta
    43201 gccgtgtcaa tgtttgctgc tggtcctata tcagctaatg cacttgatac aatttatact
    43261 attcaaggaa aagataaata tgaaacggct gctcttatag ctgatgaaca aaattatact
    43321 acagctatat taattaatgc agacagcaca atggctgatg gattaagtgc gagtggactt
    43381 gcaggagcaa caaatgcacc aattttttta actaagaaaa ataacatacc taatgcaact
    43441 cttaaaagag tagagaaagc taaaaaggta tacataatag gtggagaaag ttctattgat
    43501 aaagcaacag aaactcttct aaaagataaa ggaatagagg ctaaaagact tcaaggtagt
    43561 gatagaatta agacaagcta taatgttgca aaagaaataa actcaattaa caaagtaaat
    43621 aaagttatat tgactaatgc ttttaaagga gagcctgatg caatgagtgc tgcacctgta
    43681 gcagttagag ataaagcagc tatagtatta actgatggaa aaagtgttcc atttaataca
    43741 actggtgtag aaagttatgt aataggtggt acttcatcaa tgagtgacaa actagttaat
    43801 gatactaatt caactagatt aggtggagta gatagatatg atactaataa aaaaatagta
    43861 aataagttct ataatggcgc aaaagaattt tatatagcta gtggtactga tttagtttat
    43921 gctttagttg cttcaccaat ggctaaaaat aatcctattg tactagttga tattggaagt
    43981 aataaagata tacttaaaaa tgctgcaaaa gtgactggga taggaaatct aagtgataaa
    44041 attatgctag agtgtgaaaa taccatcaat aatattagtc ttccgtcttc aaataaaaat
    44101 ataatatgtg gattaaagat tgattttgat tcaaagcaca taatttggca agataaagga
    44161 agttatcttg aatgttatga tgataacctt gaatattata ctgaaaaata taaagaccca
    44221 acagttccta taaatataga aaatacaagt acacaaaatt tagatgtaac aaaattaaaa
    44281 gtttatggag aagctaattc aacattatat atggggcaat atgctaaaat aaaaatggat
    44341 tttaatagtt tcggtgtatt aaagccagga gaaaaatgta ctatttattt agatataatt
    44401 tcattagatc catcaagaag catgacatta acattttctt atgtaggtga taaagaaaat
    44461 tataaatatg aacaaggatt ggcaagtaga atattatttt ataacccaga tggagaagat
    44521 ttttttgaat ataaataact agtgggtatg taaattaata agggttttat aagtttaatt
    44581 tttttatttt cgttttatat taactatgtg gtatgtaaat gtctcgatat tgctcatatg
    44641 ttgagttatt atatttagtt tcatatgaac tatatggatt ttaaaattaa aaatacttaa
    44701 aaacatttac tttaatagta ggtgtttttt tgattaaaag aatattatta taatgtaaaa
    44761 agtaataaat aggtaaaata tgtaagaatt atatgttata atatttttag caagaagatg
    44821 taatctacaa tttatagagt ggagttcatg tatcaaaaaa ttatcctccc gacgctaaga
    44881 agggaggtga atatacatgg ataatttttt acaaggcata ctagcaagtc tatctgctag
    44941 cttaatagtt tatatagcta gcaaactatt tagaaagcgt aaaaaaccac tcaaagcggc
    45001 aactaagagt ggttgggaat ttgatttaaa aatcagattc cataaaacta agtaatttct
    45061 aaattatgaa ctccactcta cagcaaaata gattgtagtt cttcttgctt ttattatatc
    45121 acaaattggt acagatattc aaaaataata tttttatgat ataataaagt catagaaatt
    45181 ttgcagtgtt cgattttttg aagaaattaa ggcttaacag ttgaaatata aggcattgag
    45241 gacttgtgat aagtgttatc aattgcacta ctcatggttc actgcaaatt tgagagattt
    45301 gtatatgtgt aggcattgga aatactcaat ttattttggg gttttatatt aactatatgg
    45361 aatgtaaata ttttttttat atataaactt ctaaactttt acaaaagttt tatattaact
    45421 atatggaatg taaatacact tccaacaagc attgtagggt tgaagtctac aggttttata
    45481 ttaactatat ggaatgtaaa ttaaatcgta tttataatta tatctacact tagtaaatgt
    45541 tttatattaa ctatatggaa tgtaaatcca atagaccctc caataactcc agatattcct
    45601 tctggtttta tattaactat atggaatgta aataatgaac tatctaaacc aaggtcataa
    45661 tttaattgag ttttatatta actatatgga atgtaaattg tatccaaaaa attacaataa
    45721 tcatacgaat tgctaatata agcagtcaat atatgtgtac atttatccat tttatctcta
    45781 aacatataaa ttattatccc cctaaaaaac tttcataaaa acaaaaagaa caatatctct
    45841 ttggcaactg gctaacataa ctcataagat atttatataa gtcttagtcc ctatagcttt
    45901 gcgtcactag atttctctag ttttgccgat ttagttttat tctataacta aataatacaa
    45961 tagaattagt tattattcaa caagattgtt tgaaaattga ataaatttat aggtatgaac
    46021 gtaatttcac acttaaaaac agactaaata cgtagaatat atagaaaaat ttacctgtag
    46081 tttttgtgat aaaaagctcc tattattaat ttaagctaga taagtttgag gaagtgacat
    46141 aaattgaaag aaggaatata ttatgttgaa taaaaaatta ccagatgcag aattaaaaat
    46201 tatgaaatac atatggaata ctggttataa aactgtaata tcaaaagatg ttgcagatta
    46261 aatagaaaaa acatatgctt ggaagcatac aactacaatt acacttttag ctagattaac
    46321 taaaaaaggt tttttcatat cgcagagaat tgggaaacat gtacactata gagtattaat
    46381 aaaagagaaa gaatatctca aaatagaggg aaaaagaatt tttggaggtc tacataacaa
    46441 tccattatca gaactaattt caaaattaca tgatggagaa gaaataactg aagaaaaaat
    46501 aatagaaata ggaaattgga taaaaagctg gaaagatgaa gattaataaa taaaaggtag
    46561 ctactaatat aagtgctacc ttttttcttg tggataatat tggggataag ttgtggaaaa
    46621 tttgtgtaaa aattgtggat aaaatatttt gctgacattt aactgacata agtattagat
    46681 tttgatttaa aaatgttgaa atatcaataa ataattaaat agaagttatt agaattaaca
    46741 atagattcct ttttcaaaga agtctttgat ttcatcaagg ttatcagttt ttccaagtgc
    46801 taagataagt tttattctag ctttttgacc tggtaagtcc ccaccaaata tacaaccaag
    46861 attttttaaa tctctaccag aaccaaagta accataacta tcgaatactc tacctgaatg
    46921 acatctagaa actataacta caggaagtcc tttttctcta gcatattcaa ctccagaaag
    46981 catttgagga ggaatattac ctctgcccat tgcctcaata actatacctt tataaccact
    47041 atcaacagca aatcttataa agtcagcatt ttctcctaca tatgctttaa ataaggcaac
    47101 tttagattct accttatcag tatctataat tgttctattt acaatatctc ttgtaaggac
    47161 aagttcgttg cagtcaatta ttcctaatgg gccactagtt agagatttaa atgtatttag
    47221 agaaagagta tttgttttag tagcttcaga agctaataat acttcattgt ttaaaactac
    47281 aaggactcct tttcccatag catctttgga tactgcagta caaactgatg cagataaatt
    47341 acttgaacca tcatatccaa gttcagaact acttctcata gcacctgtga ctattacagg
    47401 tttgatgttg tcaattgtaa ggtctagaaa ataagctgtt tcctctaaac tatctgtacc
    47461 atgtgttatt acaacacctg taatatcttt tcttgctaat aaatcattta cataattttt
    47521 caattccatc attctataag gtgttatgtg aggtcctgga atttcatcaa aattaaaaac
    47581 ttcaacatct gcaactttat caatgttggt aaccattgat agtatttgtt cacctgataa
    47641 agttggtata gctgctccga ctttatcatc tactgtcata gatatagttc caccagtaaa
    47701 aactatggca acttttttct taatactcat actattctct gcctttcata aataaaattt
    47761 ataattccga taggattata tcaaaaaaag tagttaaggt ctacataaac tcttttattc
    47821 atataattta gatatttcag tgtaatataa ttatttctta attttttgcc attcaacgat
    47881 ataaccattt aatatctctc ttatggcttt tcctatctta gtataagctt catcatatag
    47941 atttgctaga gatattctaa ttgaccattc agggccatag aatccatttc cactaagtaa
    48001 aactactgaa tagtcattag ctaatttata aagaacatct actggagatg cagttttact
    48061 tataaattta aataagtctt ctccgtagtt taatttagcc cattcttcaa tatcaaattg
    48121 agtgtaatat gcagcattgt ttttgttttc attaattgga agctctaaag cttcaaataa
    48181 tagtttttga cgtctatggc agatactcat attaagtttt ttgtaggcat ctactttgtc
    48241 aatcaatgca aaagcagaga aaaacgccat ttgtacttgc tgtggagtag aaagaccagc
    48301 agtatggttg agagcaacaa gtctgctatc agcaacaact ctttccataa aggaaagact
    48361 agaagggtta agactcatat cactgtaacg cttatctact gattttttta attctccagt
    48421 taaatcattt attttcttat caaaaacatt tttcttatga agggcaaatg taccaagtct
    48481 ccatcctgta actccaaaat attttgaata agaatatact ccaacagtgt tgtaaggtag
    48541 ttttgacatt aaggatgaaa aatcttctac aaaagttcca tatacatcat ctgatattat
    48601 cattaaatct ttattataat tttcaattac atctattaga ttattacaag atgtttcatc
    48661 catagctata gaagcaggat tattaggatt aacaacgaat aaagctttaa tagatttgtc
    48721 acgaagtttc tctaattctt tttttgtata ttgccatgta tgagcacctt tttcatcaac
    48781 ttcattagca tttatattta ccactttaaa gtcgtaacga ggaaggttag gtatttcaag
    48841 ataaggtgta aatattggag tcattaaggc tatggtatct ccttttttta gaagttcatt
    48901 tgccattaat gaatcaaata tatagcacat agcagctgta gcaccttcaa cagcaaaaat
    48961 ttctacatca ccatatttac ctgatatatc atatttcatt tcttgaacta ggtaatcgtg
    49021 tactattttt tccatatgag gtaacattct atctggaagt ggatagttat caccaataat
    49081 tccatcagct agttcatgaa caaattcatc tccatcaaat ccaagttcat ttataccaaa
    49141 gtttataata tctctagcta aatatgctcc aggcatatct atattttcat ttataaattt
    49201 aaaaaatctt tctttaatac cctttttttg aggcattcca gccaaatgac ctaaatccca
    49261 attagaacga gtttcagtaa tagcgaaatg accaaaagta aaaaaggctt ctctagcagt
    49321 tgaacaagtc cagtttggat ttccacgacc tgcatcaagt aattctctgt tattttcttt
    49381 tgcagtgtat tttgcaatat ctattaattt gtccttaaat tcaaaagggc ttatttttcc
    49441 atatatgttt ttgatttctt tataagtatg atttttcatg ttaaattcct ccttatgtaa
    49501 taagtttcac atttttataa taaaataaac aagttgcaaa aatgattata ctttaattat
    49561 aataggttta tagaaaaagt aaagtatgaa attaaaataa taactctatt tagccttat
//
LOCUS       DAJMZY010000020        48757 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.020, whole genome shotgun sequence.
ACCESSION   DAJMZY010000020 DAJMZY010000000
VERSION     DAJMZY010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 48757)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48757)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48757
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.020"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            complement(105..965)
                     /locus_tag="OE968_001099"
     CDS             complement(105..965)
                     /locus_tag="OE968_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-ADP-ribose hydrolase"
                     /protein_id="HCP7218389.1"
                     /translation="MAMKWRDYADDVNLFEDFDKTIKPLTDEQRRKNINTLIAYFSKE
                     VPSKIYNLSNDEIKPRDILRGLLNVYPPKEIAPEILNMLHNLLLIECEERELVDVNDI
                     EEVEEGIAIWRGNITNLRADAIVNAANNKLLGCLQPLHLCVDNEIHSCAGPRLREDCD
                     KIIKKQGHLEYTGDAKITRGYCLPAKFVVHTVGPIVSGGQPSKEQEKQLLHCYKSCLN
                     TIKEIDEIKNIVFCGISTGVFGYPKKEAANLAVSRVRLWLKENPEKNLKVVFNVFTEE
                     EEEKYRRIFK"
     gene            complement(1282..2610)
                     /locus_tag="OE968_001100"
     CDS             complement(1282..2610)
                     /locus_tag="OE968_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010963854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-alpha-glucosidase"
                     /protein_id="HCP7218390.1"
                     /translation="MEKFSVVIAGGGSTYTPEIILMLLDNLDRLPLRAIKLYDNDEER
                     QNKVAKACEILIKEKDPNIEYLATTCPKEAYTDVDFCLAHIRVGKLEMRELDEKIPLK
                     HGVVGQETCGPGGIAYGMRSIEGVLENIDYMEKYSPNCWMLNYSNPASIIAEAVRRLR
                     PNSRVINICDMPIGMEHNIARIAGLKSRKHMDIRYFGLNHFGWYTSIKDKKGNELLPK
                     LVEHIKEYGFINGEEGMKNDKKDSWFETNLFTKEIVKTDLTTIPSSYLKYYLFPDYVV
                     NHSDVNYTRANEVIDGREKEVFGSCALIEKQGHSKGSGLKIGIHAEFIVDLATALAFN
                     TQERMLLIVQNNGAIENIQDDAMVEIPCIVGKDGYEPLSIGKIPTFQKGLIEQQLAVE
                     KLVVDAWIEKSYNKLWQALMLSKTVPSATVAKELLDDLIEANKNYWPKLN"
     gene            complement(2758..3087)
                     /locus_tag="OE968_001101"
     CDS             complement(2758..3087)
                     /locus_tag="OE968_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HCP7218391.1"
                     /translation="MVPEMEEKVFSIISEAGDAKSDVMMSLKEIKKGDYNKAKHLLNS
                     ASEKIQTASKHHLELLSNAMNSEDSGTDFLVVHSEDHYSNALFAHSLVSELVDIFEMM
                     DPRINKN"
     gene            complement(3111..4400)
                     /locus_tag="OE968_001102"
     CDS             complement(3111..4400)
                     /locus_tag="OE968_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCP7218392.1"
                     /translation="MEALQNNLRRFLLPIAQKIEKQRHLQAIKEGMISITPIIIVGSL
                     SMLFMALNNMLPEGSAKTLLSENMDTLLIPNKFTMSLLSIYSAFFIAQALAKKYNLNH
                     VEIGMTAVVAQLVVCGQVVDGVLDTSYLDAQGLFVSILVALLVVDITKFMNDKNLVIR
                     FPKEVPSVVNKSFRNLTPMIVCIMLFTAIAAITKNVSGQPLPAIIMNFLAPAISSVDN
                     VFAVTIILFITQLLWFFGLHGAAITSSIWMPIAATYMAENATLIAAGGDPKYVFTIGF
                     YYGFLQVTGSGITLGLVYLMSRSKCKSFNSMGKVVILPSLFGINEPVIFGTPIVMNPY
                     MFVPFVFGPVLVGALNFMALKVGLVGLPIAEPPGFLPPGVAAFLMTLDWKAIVLVFAS
                     IILMTLIYYPFFKIMEKEELNKNAELATTLDDDSFDF"
     gene            complement(4416..4742)
                     /locus_tag="OE968_001103"
     CDS             complement(4416..4742)
                     /locus_tag="OE968_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCP7218393.1"
                     /translation="MNILLVCANGASTGVLVEKMKSFCSEHEKLKTKTINIEATSFEN
                     LKSYIEANDTDVVLVAPQIRFKEDDVVEACKNYKIAVGLIDTKHYGRMDAPSVMKSAI
                     ELYKNR"
     gene            complement(4877..5506)
                     /locus_tag="OE968_001104"
     CDS             complement(4877..5506)
                     /locus_tag="OE968_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218394.1"
                     /translation="MQDKILRDKKANDPWARMTTRNGFSADEIISSFQKAIRRNMVEE
                     ACEFAYELYISSPELEDKLWRRILTISVEDIGMGDPSAVIIINNLNQVRKEYSYADGD
                     RPLFFIHAIRYLCACEKDRSSDLLKNIIIKGFAMGKVPEVMDVALDKHTYRGLEMGRD
                     SFHFLNEASIVIPEKEVDNDYKERYLKILEKYKQEEVIDTAFKFNHWQY"
     gene            complement(5722..8379)
                     /locus_tag="OE968_001105"
     CDS             complement(5722..8379)
                     /locus_tag="OE968_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HCP7218395.1"
                     /translation="MIYKKDKVMKVLESSYRENEKGITANQLSEKTGIARNNISTYLN
                     QLFNEGMVTKIKGRPVYYIPANLNLNKNELLDTQSELLGIKKGTKVENKIKKDSFETL
                     IGKEHSLRPIIEKCKVAMLYPTNGLHTIIYGETGVGKSMIARYMYDYSIDSGIRKNKA
                     PFVTFNCADYANNAQLLMGHIFGVEQGAYTGAESSRKGLLEIANGGILFLDEIHRLPA
                     EGQEMLFTFIDKGTFKRLGDATKERESKVLIICATTENPTSTLLDTFNRRIPMKIEIP
                     SLRDRTMIERMELVKNFFKEESKSISISIKVHKEIIKSLLLYDCKNNVGQLQNDIKLA
                     VANGYLRYKRDNKEPVYIEKKYFDKSINEVSDDYREKSIKADEVITHGIEYFVFTSLG
                     EEEVINYNDINIINAVNTNLNKSVEMNIADASLFNNVKFKSMCESIRQIIKEDEEIDI
                     SESIFKSMAIYIKSVLDKSSSTNNIDLNQIRRNNRSEFKTALKIVGIIENEFDLFLSI
                     ETVAYITLFIVQAKQDEQNKIVNNINIIVAMHGETTASSMVKAVGDIIGKCSAISFDM
                     KLDKSYDEVIVDFKNLINNIDNKDVLLFTDMGSLNSFDEIIKKEKKCGVRVIPMVTTL
                     TVLEAVQKANMGLPLNDVYNSITNTRKHYFGTNEIQNKENLSKTIIIASHVSEGVDNK
                     TRKILEEKMSRYLDGIDIISVPYKTEKDLSLNITKLKESSNIVAVINEQRINIRGIDY
                     ISKKDIDKDENINKLKNIIKISIGYDDVVEGLKTSLKSSNYNRIFKDIKYVSDELFLV
                     FNIEKKYDKVIGLMMHLAFMVDGLIGNTREIEKLDKEKTLDYHKSLSKIKDIVSQLDK
                     KYNIEINEKECYQILLILEYAEIIEKDYQ"
     gene            complement(8738..9682)
                     /locus_tag="OE968_001106"
     CDS             complement(8738..9682)
                     /locus_tag="OE968_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009527644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCP7218396.1"
                     /translation="MNREKILEIKNLKQYFHLDKSTTVKAVDDISFDIYKGEIFGLVG
                     ESGSGKSTTGKTIIRLHESTGGEVIYKGNCISDKKTYKFIKKDVNKSMQIIFQDSTSS
                     LNPRMTIADIISEPLKIQGICKNKTDRMNKVYEMLKLVGLDRSYANKYPSDFSGGQRQ
                     RIGIARALSVDPEFIIADEPIASLDVSIQAQIVNLFKKLQQEKNLTCLFIAHDLSMVR
                     HISDRIGVMYNGKLVELADSNELYNNPIHPYTKSLLSAIPVPDPRYAKSRNRIEYNSN
                     GYDCSNEKSLSWIEVSDGHFVYSSKSEINKYQQNLKVV"
     gene            complement(9675..10700)
                     /locus_tag="OE968_001107"
     CDS             complement(9675..10700)
                     /locus_tag="OE968_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCP7218397.1"
                     /translation="MEHLLEVNNLSVSFKVEEGEVQAVRNVSFNLKKGETLAIVGESG
                     CGKSVLCKSLMRILPYNGYIKNGEVLLKSSDLVKKSEKEMEDIRGKNISMIFQDPMTS
                     LNPTISIGKQIAEAVIIHQGISKSEAKKRAIELIELVGIDNPEKRFKQFPHHFSGGMR
                     QRIVIAIALACNPDVLIADEPTTALDVTIQAQIIDLIKDLQHKIGLSIIFITHDLGVV
                     ATIADRIAVMYAGKIVEIGTVEDIFYDPRHPYTWGLLGSLPTLDSQDDYLYNIPGMPP
                     NLLNPPKGDAFAIRNKNALKIDYEKEPPMFKINDTHSAATWLLHPDAPEVDVPVRVNC
                     GRVISNE"
     gene            complement(10775..12343)
                     /locus_tag="OE968_001108"
     CDS             complement(10775..12343)
                     /locus_tag="OE968_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HCP7218398.1"
                     /translation="MKLKKLKVLSLVMILSLMAGCSSGGDKDKKADTPKDGKVLVYGS
                     NDYTSINPALYEHGEINSLIFNGLTAHDENNKVVPCLAKDWKFDEATNTYTFNLRDDV
                     KWHDGEKFTANDVKFTIETIMNPDNASEIASNYEDITKIDVVNDNTIKITLKAPNTAM
                     LDYLTVGVLPKHALEGKDIATDEFNQKPIGTGPFKLEKWDKGQSITLVKNSDYFVKEP
                     GLDKVVFKIVPDDKAKAMQLKSGELDLAQITPKDMSNFEKDEKNFKVNIMKTADYRGI
                     LYNFNSKFFKDKKAKGLPNALSYAIDRKAIVDSVLLGHGVPAYSPLQMGPYNNPDIEK
                     FEYNPEKAKQEIEKLGWKLGSDGIYEKEGTKLAFEITAGESDQVRVDMAKICAQQLKE
                     IGVDAKAVVVTETDWANQDAHLIGWGSPFDPDDHTYKVFGTDKGANYSAYSNPTIDKI
                     LQKARETEDKDEKLKLYKQFQVEMTKDMPYTFIAYIDAIYVGKPNIKGLTPDTVLGHH
                     GVGVFWNIADWTIE"
     gene            complement(12456..13367)
                     /locus_tag="OE968_001109"
     CDS             complement(12456..13367)
                     /locus_tag="OE968_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCP7218399.1"
                     /translation="MKPQYSDFEIVGENYILVAEDEHIETKKTLSKKIKELPYISIII
                     LSIIVIGSVFSSFIMTHEPTYMDLASSNLAPNKTFLFGTDSMGRDIYSMIWYGGKISL
                     FIGLFSTVISTVIGIVYGSISGSASELVDDAMMRFTEIILSIPSILIIIFVQAILGNS
                     NPVSMSIVIGITSWMNISKIVRTEVRQIKNSEYILAAKSMGGGFFYVLKQHLLPNFVA
                     SIMFMVVTNIGAAIGTESTLSFLGIGLPIEIVSWGSMLSLSEEALLSNRWWIILIPGI
                     FLVTTLVCITNIGNYIRKNNNKKSSNL"
     gene            complement(13351..14337)
                     /locus_tag="OE968_001110"
     CDS             complement(13351..14337)
                     /locus_tag="OE968_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCP7218400.1"
                     /translation="MLKDILKKLLQFILVMFLLSFIVFYMARLAPGDPLISYYGDGVE
                     RMSTQEKENAMKKLGLDEPIYSQYIKWISNASKGEFGISFKYKQNVTSVINDVYINTI
                     ILGGSGYILTFVLALLLGIFCTLHEDKLIDRIICKLGTITNCIPSFWVALVLILIFSI
                     NLSILPSSGAYSMGEESSILSRISHLILPLTVLILSHLWYYTYMIRNKLLEEIREDYV
                     LLCKAKGLNNRTIVFKHCLRNIMPSYISIMAISIPHILGGTYVVEKVFSYPGLGTLCF
                     ESAKYHDYNMLLVLCLITGALVVFGNMLAQIINNKIDPRMKYDRGDTNEATI"
     gene            14697..15098
                     /locus_tag="OE968_001111"
     CDS             14697..15098
                     /locus_tag="OE968_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HCP7218401.1"
                     /translation="MLLKELYSKTMYTVEENFKENGLTHQQIIVIKLIAHNQELTISQ
                     LCDEMSLAKGTVSGIISRLEQIGYIEKFKKSNDKRNTYVKFTTTGFEFATNFKIKMQE
                     SFDDIFKNCDENELSDLVKNLRNILAKVKER"
     gene            15101..15499
                     /locus_tag="OE968_001112"
     CDS             15101..15499
                     /locus_tag="OE968_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03987 family protein"
                     /protein_id="HCP7218402.1"
                     /translation="MNYKLILAIVFITSALIFYTIGVFGERKAKILKKKHVIIFWLGF
                     IFDTLGTFTMSNIANSHTFEVKSALSQNLHSITGLLAIVLMLFHASWATFVLYKDDEE
                     KKKFFHKFSIVVWTIWLVPYFIGMFIGMAG"
     gene            complement(15949..16173)
                     /locus_tag="OE968_001113"
     CDS             complement(15949..16173)
                     /locus_tag="OE968_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NifU family protein"
                     /protein_id="HCP7218403.1"
                     /translation="MREKVEKVLEEKIKPVLQRDGGDVELIDVNENGVVLVRLQGACS
                     GCPGATMTIKAIIENVLVSEVPGVTQVLGV"
     gene            complement(16208..17575)
                     /locus_tag="OE968_001114"
     CDS             complement(16208..17575)
                     /locus_tag="OE968_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HCP7218404.1"
                     /translation="MKEYIINNVEEIREELIDLSKKIWENPELAFEEKYASSIQKEYL
                     KSKGFKIEEVENLPTGFIASFGEGKPVIGILGEYDALPELSQCVSAERKPLVEGKAGH
                     GCGHNLLGVAGVGAVVSIKKLIEENKFNGTIKYFGCPAEEEGGGKTAMCINGCFDDVD
                     CAFTWHPFDINAPWRGGSLANLSVKFKFKGITAHAAQAPHNGRSALDAVEIMNVGANY
                     LREHVIDSIRMHYVITNGGGRPNVVPGFAESWYFIRGKKAKDAEHVLDRLIKVAQGAA
                     MMTETEMEYKVTDGIYDYIPNQCLTDLVYDNMVFVGCPKNTPEEEEFAKKLCDTLTRE
                     ERLGVATSLQNDKSIVESYIHKEIVDGDKDKGLAGSTDVGDVSYVIPVAQFAMAAWPV
                     GIASHTWQSCSSAGSNIGFSAMINSAKVLACSAYDVFMDTKIIDEAKIEFDKSLDGQK
                     FKPLV"
     gene            complement(17659..19194)
                     /locus_tag="OE968_001115"
     CDS             complement(17659..19194)
                     /locus_tag="OE968_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218405.1"
                     /translation="MLNNLSNININENNLIKNQYSISLLKECLNCKVIDEREVYNIQQ
                     EISLILMDLIKKYTNGQSTSVKTEVAEKLLISIWYAIDAYINKLGDIEKRVVELTAKN
                     VKKVYLGGIEILEEELVRLKDFYKLMMSRKLDTNSIAYNDTLMELSSFFKSYIVKFEA
                     QDVPVSIDYPLALDDMDVKGIYYVKNYIESIDIENRFCNLFKKKDREKLFYDYGVTYK
                     IDCDAILVNLFELIINNCIFSTILGNEVTNLEISKYEYEFLEKQFKNMYNNITEDKVI
                     DSEESNIIELIEVDDSFNTEVDSNLDYNDFEEINREIRINKKITLLLMEAIEVLIKRL
                     SIEDEDVIRYIKKYEKIFIESVLSSIKSNTFKSMVTVSKNKKEHLEDYIVDDESKLDD
                     ESFREIFNEILDSTSIIEKIRIIKENINAKKDFIDILESECLFGEEYLMLFASLSELE
                     LAILGSVVFYEDIRMREINILEFMLNEKTETTLWKIEYIKFMKRQSEDKIYSIEEHMN
                     KIN"
     gene            complement(19217..19651)
                     /locus_tag="OE968_001116"
     CDS             complement(19217..19651)
                     /locus_tag="OE968_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218406.1"
                     /translation="MISPIILSSINQNLKEIERNELLETNIESGDYGLALSESDVKDI
                     INSRDNTLKGYGRIELDIKVTKQLIENIYTSQYTNVDNYLEAINDMQEIFYYLKNETD
                     DKICDDEIIEILGEFYEKFSGNMDNVRGEADEFAKKFKFGEV"
     gene            complement(19911..20822)
                     /locus_tag="OE968_001117"
     CDS             complement(19911..20822)
                     /locus_tag="OE968_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CGNR zinc finger domain-containing protein"
                     /protein_id="HCP7218407.1"
                     /translation="MNKKIELIGNFASDWIRYSDYEYKITEEDELYIVPTEDAVFTMY
                     NPFDVADDIIVDIIRIGQEALQDISKETKEMKLKKEVLEFVKKYGLLGLIYSSVYNRD
                     IVGEERVLMIEKNYITKENILSTDEYVNMFIPFASDEDVYFKKYRRGIDVSKREESPK
                     FFGKRPLILDLVFSKFYTEQLDWIVSFAKDMCKHFNQICVYKNTSNLLTESVTIMSGG
                     FNPQKIGFSISQLDKPIIAWEFDSLKTAIETIYAFAITSEPSSLNKCKYCGKIYIPTN
                     SKSQYCSPSCRNCSNVKKSRSRAKKDK"
     gene            21118..21471
                     /locus_tag="OE968_001118"
     CDS             21118..21471
                     /locus_tag="OE968_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HCP7218408.1"
                     /translation="MDRKRELKQLYKEMKFDTGVFIIKNDITKKIYLGKSNDIKSKFN
                     SLKFQLGAGSCMIKELNNEWKKYGEKAFTFEVLELIKHDDNKTEKDYLEELDILEMVW
                     LEKLKEDNTYEIYSI"
     gene            complement(21690..22631)
                     /locus_tag="OE968_001119"
     CDS             complement(21690..22631)
                     /locus_tag="OE968_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp25"
                     /protein_id="HCP7218409.1"
                     /translation="MRISKKVLALGISALLLSVSFPTSINALDKIENIQGVDKYETAG
                     LISDKQDFTTAVLINADSTMVDGIAASGLAGVNNAAILLTNKDDIPEATLQRLNRVTK
                     IYVIGGENSISKDVEKMLLMRRMQVIRIDGVDRVDTSYKIAGEIEKIKNSDKMFLVNG
                     FKDEADAVSVASVAYRDGAPIILTKDIPSAEEDTDLDPWFGVSPVPVYAIGGESTLSD
                     YIVSRYRATRIGGVDRYQTNKNVIEKFYNGAKEFYITSGDDLVYALVASPLAKNAPVV
                     LVSNKSDKSILSGASKVTAIGISDKSIIEQCLDAVKK"
     gene            complement(22732..23967)
                     /locus_tag="OE968_001120"
     CDS             complement(22732..23967)
                     /locus_tag="OE968_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HCP7218410.1"
                     /translation="MKILHIITQKPNSTGSGIYLSGMIKGFEKIGHKQAVIAGIDVND
                     DVNCFPSEVSFYPVKYNCGELNFPVVGMSDSMPYESTRYKDLNIDMINRLKYQFKVNI
                     DKAMNDFKPELIICHHLYLLTAFVREMVKDIKVMSICHGTCLRQLNTIDLEKEYIIAN
                     IRKLDLIFALHENQKYDIIKTFGVSQSKVVVIGSGYNDDIFYNKNYKIKDDKIKIVFA
                     GKICKSKGLIPFIKAISKLKYSKDLIEVNFAGTGSDIESYNEIVKLASKSPFKMNFLG
                     KLEQRDLAELFNRSQIFVLPSFYEGLPVVVLEALSCGTDVITTDILGVKEWIGSEINN
                     SGKIEYVSLPFMEKEGIPKDEELYDFENNLYNAIDSKIQSLLNNSNKKTSVDMSKKTW
                     DGLAYRINEVILMDELCLI"
     gene            complement(24011..24865)
                     /locus_tag="OE968_001121"
     CDS             complement(24011..24865)
                     /locus_tag="OE968_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218411.1"
                     /translation="MALNIRNYSLLCNQGTAKFNEDVVGINPFGAWVLDGATGLNGKN
                     LVSTESDARWYVQWWNRYLYKNINKEESLKSIINTGIIEVKKEYELRLNGFKVEKLDL
                     PSSSIVVVKFHENKVEYFLLGDCALFIKNGDSKVIKDRSICKFDNTVFDEMSKLSNLE
                     EMAFDEIRTSVMDTIVSNRLKKNTKEGYWILDFDEEAVENSIYGYIEIKKDFQLMLTS
                     DGFTSACDRYNLIKEEELIRIAEKFGIGYIHNKVRDFEDNDYKAVKVPRFKVKDDSSC
                     LYLDIYND"
     gene            complement(24993..26168)
                     /locus_tag="OE968_001122"
     CDS             complement(24993..26168)
                     /locus_tag="OE968_001122"
                     /EC_number="2.1.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolecarboxamide
                     formyltransferase"
                     /protein_id="HCP7218412.1"
                     /translation="MARELELKYGCNPNQKPSKIYMKNGELPIEVLNGKPGYINFLDA
                     FNSWQLVKELKEATGLPAATSFKHVSPAGAAVGVPLSDTLKQIYFVDDLELSPLACAY
                     AMARGADRMSSYGDFIALSDVCDKETATIIAREVSDGIIAPGYTDEALEILKGKRKGN
                     YNIVKIDENYTPEPIETKDVYGITFEQGRNEILINEDLLKDIPTDNKIFTDSAKRDLI
                     IALITLKYTQSNSVCYAKDGQVIGVGAGQQSRIHCTRLAGNKADTWYLRQHPKVLNLK
                     FKKDIGRPDRDNTIDVYLSDDYMDVLADGIWQNFFEEKPEPLTGEGKRAWLKTLTGVA
                     LGSDAFFPFGDNIERAKRSGVSFIAQPGGSIRDDNVILTCNKYNIVMAFTKNRLFHH"
     gene            complement(26267..27151)
                     /locus_tag="OE968_001123"
     CDS             complement(26267..27151)
                     /locus_tag="OE968_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarylacetoacetate hydrolase family protein"
                     /protein_id="HCP7218413.1"
                     /translation="MKFVTFCSSNEEKIGVFNSETNSIYEINSLGLSKLYTDMNDFIE
                     NVSTGDLEKIKNNSFENAKCYKLEEVKLCSPIVRPKKDIICLGLNYKDHVNEIPDGVI
                     KNVVMPDYPIYFSKRADKIIGVDDKISLHGDLVEKLDYESELAVIIGKEGINISKEDA
                     YEYIFGYTIVNDISERALQDKHVQWFRGKSLDTHTSMGPCIVHKEEFEHPLKLDISSV
                     VNGEVRQDSNTEYFIFDIPTIINDLSRGMTLKPGDIISTGTPAGVAMGMNPQVYLKHG
                     DIVECKVEGIGVLKNIVD"
     gene            complement(27383..28069)
                     /locus_tag="OE968_001124"
     CDS             complement(27383..28069)
                     /locus_tag="OE968_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HCP7218414.1"
                     /translation="MKYSYKKCIIDSILLMFIVQILRMILNYVLLSQFEFTLENFNII
                     NLISFTLVGLSLILFLKDNSLYNKVRNRKITEAFEENKNNILIEKCKLILFVVVLSLA
                     IIVTYCTKGYVLFNVTMMTLSVLIVPIFEELFFREYIWNYLSNFIKSKSKIICITSIL
                     SGIYNIGYIDVIRNYVILYNNSSYTFEVIISKIMIGTVFGIVLGLVKYRFRDVGFCIL
                     LRSLFAIFIR"
     gene            complement(28097..28408)
                     /locus_tag="OE968_001125"
     CDS             complement(28097..28408)
                     /locus_tag="OE968_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HCP7218415.1"
                     /translation="MGIFKTKMDEDWKVNYIKEFNEMRDSYESKLQKKQFEVDSLKSE
                     LDRLRSYKNSLKPKEKQITDDDINNIKSLRRDGLSYKEISNQTSWSKATVSRVLNGLY
                     D"
     gene            complement(28597..29118)
                     /locus_tag="OE968_001126"
     CDS             complement(28597..29118)
                     /locus_tag="OE968_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HCP7218416.1"
                     /translation="MIGFLKKRRSIRKYKDVEVEKEKLDKILKAALLAPSSKGLRTWE
                     FIVVDDKEKLINLSQCRTKGGGFFLKNAPLAIVIIADKEKNDVWIEDASIAASYIQLQ
                     AHELGLGSCWIQVRNRMHDDNIEADKYIREELKVPSKYSVECIISIGYPDEEKKAYGD
                     SDLDYKKVHFNNF"
     gene            complement(29215..29709)
                     /locus_tag="OE968_001127"
     CDS             complement(29215..29709)
                     /locus_tag="OE968_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCP7218417.1"
                     /translation="MIRKANMNDLESIMQIIKSTVEEMKTYNNTQWDENYPLEKDFVS
                     DIKKQDLYIYEVDGEVAGFICLNYEEPEEYLGLNWSSNKKAMVIHRMAVNPNFRKTGI
                     ASKLVDFAEKLAVENNVSYLKSDTYSINSKMNLLLTKCGFIKIGEMSFLGKEKSFYCY
                     DKIL"
     gene            complement(29743..30216)
                     /locus_tag="OE968_001128"
     CDS             complement(29743..30216)
                     /locus_tag="OE968_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HCP7218418.1"
                     /translation="MVVSVEVCLIKTLDSNILREVGTLSRAVNSINDIKYKELKLQKG
                     QFTFLTRICENPGINLVELSNMLKVDKATTTKAIQKLIKAGYVDKKQDKFDKRGYNLT
                     PTDKSLEVYELIIEEENRSIEICFDNFTDEEKQVVTKLLEKMSKNVENEWFKVKR"
     gene            complement(30542..31537)
                     /locus_tag="OE968_001129"
     CDS             complement(30542..31537)
                     /locus_tag="OE968_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isocitrate/isopropylmalate dehydrogenase family
                     protein"
                     /protein_id="HCP7218419.1"
                     /translation="MYKVTLIPGDGIGPEVAKAMKKVVEATGVEIEWEEVNAGEAVIE
                     EYGTPLPEYIIDSIKKNKIAIKGPITTPVGKGFRSVNVTLRQALDLYVNLRPIKSFKG
                     IKSRYEDVDLVVVRENTEDLYAGIEHKIGDYAAESIKIITRSASERIVDFACNYVKDN
                     KRKKVTAIHKANIMKMSDGLFLDVFREVASKHGVEYDDLIVDAAAMNLVLNPENYDVM
                     VMPNLYGDILSDLGAGLVGGLGIIPSANIGKDCAIFEAVHGSAPQIAGQNKANPTALI
                     QSSVMMLRYLGEYENAQKIETALEKVFLEGSKLTVDLGGSASTTEFADEVCKYIV"
     gene            complement(31559..33484)
                     /locus_tag="OE968_001130"
     CDS             complement(31559..33484)
                     /locus_tag="OE968_001130"
                     /EC_number="4.2.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aconitate hydratase"
                     /protein_id="HCP7218420.1"
                     /translation="MGDNIVYKIIKKHIVDGEAVAGSSIGIKIDQTLTQDSTGTMTYL
                     QLEAMGIDKVKTKRSVAFVDHNMLQQGFENADDHKYIQTVADKYGVYFSKPGNGICHQ
                     VFLERFSTPGDTLLGSDSHTPTAGGVGMMAIGAGGLDVALAMAGGAYYIKAPKVCKVN
                     LVGKLNNMVSSKDIILEVLRKQTVKGGVGKVYEYGGEGVKSLSVPQRATITNMGAELG
                     ATTSIFPSDEKTLEFFKSQGREEAWIELKPDADAVYDEEITINLDELKPLAAKPHSPD
                     NVDEVENIGKIKIDQVAIGSCTNSSYEDLMKVAQILKGNKVHKDVSLVIAPGSRQVME
                     MIARNGALADIISAGARILENSCGPCIGMGQSPGTDSVSLRTFNRNFYGRSGTLSAQV
                     YLVSPEVAAVSAIKGVLTDPREFDIKFTNLDVNEFLIDDSMIIKPADVGSDVEVVRGP
                     NIKPFPLNTELSQSIGGKVILKTEDNITTDHIMPSNAKLLPFRSNIPYLANYCFNTVD
                     TEFPQRAKDNNGGFIVGGDNYGQGSSREHAALAPLYLGVKGVIVKSFARIHKANLINS
                     GIIPMEFCDEKDYENISLLDNLEIPNILDNLGSGILEVKNTTKGTSFKVKVELSAKEV
                     DVLKAGGKLNYTKNQAN"
     gene            complement(33509..34702)
                     /gene="nifV"
                     /locus_tag="OE968_001131"
     CDS             complement(33509..34702)
                     /gene="nifV"
                     /locus_tag="OE968_001131"
                     /EC_number="2.3.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homocitrate synthase"
                     /protein_id="HCP7218421.1"
                     /translation="MCVISKDRAKEIKIVDTTLRDGEQTAGVVFANREKIMIAEMLSD
                     LGVDQIEVGIPTMGGDEKNVIKHICSRNLKSDIMAWNRAVIKDVEESISCGVDAVAIS
                     ISVSDIHIENKLRTSRGWVLENMAKTVEFAKKNGLYVSVNGEDASRADIDFLTEFINV
                     GKQAGADRFRYCDTVGVMNPFSIKNAIETLYERTNFDIEMHTHNDFGMATANALAGIA
                     AGANYVGVTVNGLGERAGNAALEEVLMALKCVYKCDLNNIDTRKFRGICEYVAQASGR
                     ILPTWKPVVGDNMFIHESGIHADGALKDPHNYEPFDPSEVNLERKIVIGKHSGRAAVV
                     NKLSEYEMYISPENATKLLNAIRATSIRLKRSLMDKEILQLYCDILAHEKGTTEEEAV
                     RGSYI"
     gene            35164..36273
                     /locus_tag="OE968_001132"
     CDS             35164..36273
                     /locus_tag="OE968_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HCP7218422.1"
                     /translation="MDFKSLGISENTINILKKSGITTPTPIQKESIKLIKEGKDVIAE
                     AQTGTGKTLAFLLPIFENISLDINDIQVLILSPTRELAIQITEEAMKLKESKDVSILA
                     AYGGKDIGSQIKKLKGNIHMIIATPGRLLDHLNRKTIDLSKLKTFVLDEADQMLLMGF
                     KNEVEAILKETSNKKQTLCFSATINSQVKKLAYRYTKNPVVVSIQKEEITLNNIKQEV
                     VETTDRKKLDALCKVLDEDNPFMAIIFCRTKRRVDNLEEALAIRGYNCQKLHSDIAQS
                     KRERIMKSFRNLDIQYLIATDVASRGLDISGVSHIYNYDLPETPEDYIHRIGRTGRAG
                     EEGYTCAFIDPKNERMLSEIETAIESKISRRIIEL"
     gene            complement(36650..37834)
                     /locus_tag="OE968_001133"
     CDS             complement(36650..37834)
                     /locus_tag="OE968_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218423.1"
                     /translation="MQKSVKKAKVTGSMLAIFGVASVLFSSHAGGGFATGNQETQYYV
                     QYGWTAPLMAILAMIILTATMREVIIMYNNNNCRNYKDLFCELWRPYPKLEIIWEIYY
                     YLMVLIAVSAVIAGAAAVFQSIGVNYFVAVFIIGVVLLVFTIFGAMLVSKAATAMTIA
                     ILVCTLTIFIVGIKAKVPEITEILSNRTSFTPGYIKPILNTFIYAGFQSVVIPTLAGC
                     SRPLLKNSKEATKAMIISFVMNAIALGLAVTMLMGWYREIIAAGQTTLPTLYVAGQSG
                     NHTIYIIYNVALFLCLMSTGVTTIFGLVNRFEDHKALSFLSSRMKRRVFTACAIMVVS
                     MLISLTGLSNIVKYGYGYCGYLGLFTIVIPFLTLGHYKNKKFAKENPEAKWPAELNEN
                     VN"
     gene            complement(38436..39251)
                     /locus_tag="OE968_001134"
     CDS             complement(38436..39251)
                     /locus_tag="OE968_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HCP7218424.1"
                     /translation="MERLKIQVLVDNNTYIDRYFVGEPAVSYYIEIDGNRILFDSGYS
                     DVFISNAEKLNIDLGNLTHVVFSHGHNDHTRGIQFLENRYDLSTVELISHPNCFIPRK
                     HGEKSIGAPFSAEEIKNIFMYNPKDKPFNLSKNCVFLGEIPSINDFEKRAKIGKCKIG
                     DLWEDDYVLDDSAIVCKTDKGIFIVTGCSHSGICNIVEYAKKVCGDDRVIGILGGFHL
                     FELNNRLDSTIQYLDKEEIRMLYPCHCVSFKVKAKMNEILNINEVGVGLTISI"
     gene            complement(39548..40990)
                     /locus_tag="OE968_001135"
     CDS             complement(39548..40990)
                     /locus_tag="OE968_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HCP7218425.1"
                     /translation="MSIYKCSVCGYIYDESKNDKTWDELSEDWECPVCTKGRSYFGKI
                     STVYYEEDEKIAEDIVEDESKLNTEKEGDLNYLSTYLRRDDEVEKHMDIIHEMAVTGK
                     SIIEPMRTKLPVISWDDILIMGAQLNPLPLNEHDEVNTTTIIGKKAKKPMIIENPVYI
                     SHMSFGALSKELKIALAKGAAQNKTAMCSGEGGILPEEKEASYKYIFEYVPNKYSVTE
                     ENLKNSDAIEIKIGQGTKPGMGGHLPGEKVTEEIAKVRNKPVGQDVISPSCFEEIQSK
                     EDLKKLVDELREVSEGRPIGVKISAGHIEKDMEFIAYAKPDFVTIDGRGGATGASPKL
                     LKDATSIPTIFALYRARKYIDTHGLDIDLVITGGLRISTDFAKAIAMGADAVAIASSA
                     LMAAACQQYRICGSGKCPVGVATQDEELRKRLHIENSANRVANFLNVSLEELKTFARI
                     SGHKDIHDLSVDDLYTVNSEISNYTNIQHV"
     gene            complement(41117..41503)
                     /locus_tag="OE968_001136"
     CDS             complement(41117..41503)
                     /locus_tag="OE968_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="desulfoferrodoxin"
                     /protein_id="HCP7218426.1"
                     /translation="MCSEQKFFICETCGNLVGMIQSGGVPIFCCGKPMKELVPNTTDA
                     AVEKHVPVIEVDGNNVTVKVSSTTHPMTKEHHIAWVYLMTEQGGQRKCLAVDGEPVVK
                     FALNDDDKVISAYAYCNLHGLWKAEL"
     gene            complement(41540..41929)
                     /locus_tag="OE968_001137"
     CDS             complement(41540..41929)
                     /locus_tag="OE968_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HCP7218427.1"
                     /translation="MKFSKQRELILNEILNNPVHPTADYLYENLKKDNPNLSLGTVYR
                     NLAQLTEHGFIRKVSIPGYPDRFDGRIDNHYHIICEVCGEVYDLESEVLNNLQELISE
                     ETDIKITSYNISFKGICNNCKRCSQVG"
     gene            complement(41961..42497)
                     /locus_tag="OE968_001138"
     CDS             complement(41961..42497)
                     /locus_tag="OE968_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rubrerythrin family protein"
                     /protein_id="HCP7218428.1"
                     /translation="MNLKGTKTEKNLMAGFAGESEARNKYTYYASKARKEGYNQIAAI
                     FEETANNEKEHAKLWFKLLHDGMPSTEENLKDAAAGENYEWTDMYAKFAKEAREEGFD
                     KIAYLFEAVGKIEKEHEERYLKLLENLNEGKIFKRDEEVVWQCQNCGHVYVGTEAPEK
                     CPVCDHPKAYFNIKAENY"
     gene            complement(42874..43656)
                     /locus_tag="OE968_001139"
     CDS             complement(42874..43656)
                     /locus_tag="OE968_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCP7218429.1"
                     /translation="MLDIITTEFQKIKRYNILWIGVVAVLFSALLAVFQVVSSHGSDP
                     LTYESFANGVIWNNFSLSFPFGITLIGGYLINREYTDQTLKNILTVPISLRKLLVGKL
                     IAVGGITVLLSLFSFLCTFILGLLFCNINISVILVVKSLVQILSVNLYCYVAVLPIIA
                     YFGRKQNAFLTGVGIAFVYGFCGVFVAGRNLTDFYPITAGLGLVGYNNGAGTVYQPLI
                     GAMTLIVILILTTILLVFTPNYDKVMTISKKKGIKHKKYSHK"
     gene            complement(43666..44436)
                     /locus_tag="OE968_001140"
     CDS             complement(43666..44436)
                     /locus_tag="OE968_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCP7218430.1"
                     /translation="MKELLDIISCEFSKLKRLKFILISILGACLFPIPATILIAKDNL
                     PFEQLFKLVVNFGYFLLLPIVLSIVASQLFFIERDNDVLKNLATVPVPKGKLALAKLA
                     VLLFISLFYSVAGLGATIIGGFIVGIVEGVAVKLGMSIAFGIMFFVTVLPVVVLIVYF
                     NRSYIFSIILSFVYAIFNFSISLNIINFEPNNPLLSVLPAPVIMRWWMAFWGDPTGEY
                     TVLRQPYLLSTPACVGILCLITIIAVLLICMIYKKQEN"
     gene            complement(44420..45343)
                     /locus_tag="OE968_001141"
     CDS             complement(44420..45343)
                     /locus_tag="OE968_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013273760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCP7218431.1"
                     /translation="MNNLIIETKNLTKQYGAQKSVSNLNIHVQKGRIYGLLGRNGAGK
                     TTTMKMLLGLTKPTTGEIKIFGQDIHNNEKKLLPRIGCLIESPGFYPNLTGTENLKIF
                     ARLRGIPKKNAVESALDVVGLPNNDKKLFSQYSLGMKQRLAIALAIMHDPQLLILDEP
                     INGLDPIGIAEVRTFIRDLCTERGKTILISSHILSEIALLADDIGIIDHGILLEEESL
                     AQLEEKNSKYIHFAVSDAAQAARLLETQLNLKNFKVADNYNIMLYDTDVSVAEINRAF
                     ILNNIEVSESHLCEDTLEDYFKKVTGGEGIA"
     gene            complement(45491..46426)
                     /locus_tag="OE968_001142"
     CDS             complement(45491..46426)
                     /locus_tag="OE968_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HCP7218432.1"
                     /translation="MKMDEQTIILFLLLLSIGLLFLSIFAFSKLGHIHKRLKDIEEIL
                     ADVQIGDENRKILIKPCDVMAPLVYQLNEIVYDYENKLLSLKKSDKASKQLMTSLSHD
                     VRTPLTTLIGYLDAVHSGIVIEQEREEYLEIARRRAYDLKDYIDVLFDWFRLNSDEFT
                     LSIESVEIAELSRNILKDWIPIFHEKKLNFEIDIPENRLMVNLDPDGYSRVVNNLVQN
                     VLAHSKARQIKITMSEDSRMVLLRVEDDGVGIARENLPHIFERLYKCDKGRSEKGSGL
                     GLSIVSQMVERMGGQVSVESEIGKYTVFTVSLPLI"
     gene            complement(46423..47115)
                     /locus_tag="OE968_001143"
     CDS             complement(46423..47115)
                     /locus_tag="OE968_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003020373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCP7218433.1"
                     /translation="MNKVLIIDDDKDLCILLKKSISIEQIEANYCHSGRDGLVELSKQ
                     DYQLVVLDVMMPGMDGFETMEQIRKYSSIPILMLTSKSDNYSKVHGLRAGADDYLTKP
                     FEITEFTARVLSLIRRYTRFNPKNEEPQQLSFKGLLIDLDQHTVTTNGEPMLLPPKEF
                     GVLLYCARHQGKILTKQQIYEAVWGEPYVYDDSNIMAIISRLRKKIELDPSSPIYLQT
                     IKGIGYQFNTEV"
     gene            complement(47617..48465)
                     /locus_tag="OE968_001144"
     CDS             complement(47617..48465)
                     /locus_tag="OE968_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HCP7218434.1"
                     /translation="MYITKVLNNSLLLAKDDNDEEIILMGKGIGHNYKAGSELNEKDI
                     EKIFVLHDENIKKSIIQLATEIDAEYFGIAQMIIAYGIEKYNLKLMNHIYLALTDHIA
                     FAVRRFKEGIMIENHYLFEIKEFNPKEYDIGKYAITVFKEVLGLDLPEEEIGNIAGHF
                     INAQQDNPYSDRNKRSAKIVNAILQIVHYHFSIVYNKESFYYRRFVMHLKAFSQRFLA
                     NEPSREKIDFIYEQVQKNCKEEYECVKKVGAYMYKEYSRELPRQEELYLMIHIHKILG
                     ELCENS"
     gene            complement(48493..>48757)
                     /locus_tag="OE968_001145"
     CDS             complement(48493..>48757)
                     /locus_tag="OE968_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HCP7218435.1"
                     /translation="KIHDDYRIDYLRSHINACKLAIEDGVEMIGYCPWSFTDLLSSSQ
                     GFNKRYGLVYINRTDHEILDLKRIKKDSFYWYKEVIENNGIVK"
BASE COUNT        15769 a         8822 c         5298 g        18868 t
ORIGIN      
        1 aaatacaaat tatattttat taatttttac tacttgtaaa ttattatctt atacaatgaa
       61 tttgtattat ataataagta tttttaggat tctgttacat aatattattt aaatattctt
      121 ctatatttct cttcttcttc ttcagtaaac acattaaata caacttttaa atttttttca
      181 ggattttctt ttagccatag tctaactcta cttacagcaa gattagctgc ctcttttttt
      241 ggataaccaa atacacctgt agaaattcca caaaaaacaa tattttttat ttcatcaatt
      301 tcttttattg tatttaaaca tgatttataa caatgaagca gttgcttttc ttgctcttta
      361 cttggctgac caccagatac aataggtcca acagtatgta ctacaaattt tgcaggtaaa
      421 caataacctc tagttatctt agcatctcca gtatattcta aatgcccttg tttttttatt
      481 attttgtcac aatcttctct aagtctagga cctgcgcatg aatgtatctc attatccacg
      541 catagatgta atggttgtaa acaccctaat aacttgttat ttgcagcatt tactattgca
      601 tctgctctta aattcgttat attacctctc catatggcaa tcccttcctc tacttcttct
      661 atatcattta catctactaa ctctctttct tcacattcaa tcaacaataa attatgtaac
      721 atattaagta tctctggagc aatttctttt ggtggatata cattcaaaag tcctctaagt
      781 atatctctag gcttaatttc atcatttgat aaattgtata ttttagaagg aacttctttt
      841 gaaaaatatg caattaaagt gtttatattt tttcttcttt gttcgtcagt tagaggcttg
      901 atagttttat caaaatcctc aaataaattt acatcatcag cataatctct ccacttcata
      961 gccatctctc cattcttgta ttttagactt aaaaataatt atgtatttat gtacatattt
     1021 atttatttct ataaacacct acataaatcc tgttaaaagt gtaaattttt tattatacaa
     1081 cttctctggt tatttctatt gattgatagt aaattattgt acctaaattt aatccaacta
     1141 acaagtaact aaacctactt tcctaactgc aaaatacact atgtttgcca cttgtatctc
     1201 atttgtagat aaataaagtc cctacaaata cattaactag gctatgtact aaactgtagg
     1261 aactttaaaa atatattatt cttaattaag ttttggccaa taatttttat ttgcttctat
     1321 taaatcatct agtaattctt ttgcaactgt tgcactagga actgtcttag atagcataag
     1381 tgcttgccac aatttattat aagacttctc aatccaagca tcaactacta atttttcaac
     1441 tgctaattgt tgttctatta aacctttttg gaatgttggt attttcccta ttgataatgg
     1501 ttcatacccg tcttttccaa ctatacatgg aatttcaacc atagcatcat cttgtatatt
     1561 ttctatagct ccattatttt gaactatcaa taacatacgc tcctgtgtat taaaagctag
     1621 agctgtagct aaatccacta taaactctgc atgtattcct atcttaagcc cactgccctt
     1681 agaatgtcct tgcttttcta tcaatgcaca tgaaccaaaa acttcttttt ctcttccatc
     1741 aataacttca ttggcacgag tataatttac atcagaatga tttacaacat aatctggaaa
     1801 tagatagtac tttaagtaac tacttggtat tgtagttaaa tctgttttta ctatttcttt
     1861 agtaaataaa ttagtttcaa accaactatc tttcttgtca tttttcattc cttcttcacc
     1921 atttataaaa ccatattctt ttatatgttc tactaatttt ggtaaaagtt catttccttt
     1981 tttatcttta attgaagtat accaaccaaa gtgatttaat ccaaagtatc ttatatccat
     2041 atgtttacga gatttgagtc ctgcaatcct tgctatatta tgttccatac ctattggcat
     2101 atcacaaata tttattaccc tagaattagg tctcaacctt ctaacagctt ccgctattat
     2161 tgatgctgga ttagaataat ttaacatcca acaatttgga gaatactttt ccatataatc
     2221 tatgttttca agaacacctt ctatagacct cattccataa gctattccac ctggtccaca
     2281 agtttcttga ccaactaccc catgttttag aggtatcttt tcatctagtt ctctcatttc
     2341 aagttttcca actcttatat gagctaaaca aaaatctaca tctgtataag cctctttagg
     2401 gcatgttgtt gctaaatact ctatattagg gtccttttcc tttattagta tttcacaagc
     2461 tttagctacc ttattttgtc tttcttcatc attatcatat aatttgattg ctcttaatgg
     2521 taacctatct aagttatcta gcaacattaa tatgatttct ggggtatatg tacttcctcc
     2581 tccagctatt actactgaaa atttttccat aataatatct ccttttctat ttaaaaattt
     2641 actgtattta taaataaatt tataaatact agtactttaa agtaaaaggg agttcattta
     2701 ttaaatctat tgatttaata aactatagcc aaacttcaag cactatttac aagaaattta
     2761 attcttatta attcttgggt ccatcatctc aaatatatct acaagttcag atactaaaga
     2821 atgagcaaat aatgcatttg aataatggtc ttcagagtgc acaactaaaa aatcagtccc
     2881 actatcttca ctattcatag catttgatag taattctaaa tgatgctttg atgctgtttg
     2941 tattttctct gaggctgaat ttaaaaggtg ttttgcttta ttgtagtcac ctttttttat
     3001 ttccttaaga gacatcatta catcactttt agcatctcct gcttctgata ttatactaaa
     3061 tactttttct tccatttcag gtaccatatc cttctccttc taatgacttg ttaaaaatca
     3121 aagctatcat catctaatgt tgtagctaat tctgcatttt tatttaattc ttccttctcc
     3181 attatcttaa agaatggata atatatcaag gtcataagta ttatacttgc aaatactaat
     3241 acgattgcct tccaatctaa tgtcatcaaa aatgctgcaa cccctggagg taaaaagcct
     3301 ggtggttctg caataggtaa tcctactaat cctactttta atgccataaa attaagtgct
     3361 ccaaccaata caggtccaaa tacaaatggt acaaacatat atgggttcat aactattggt
     3421 gttccaaata ttaccggctc atttattcca aatagtgatg gtaaaatcac aacttttccc
     3481 atactattaa aactcttaca cttacttctt gacataaggt acactaatcc caaagttatt
     3541 cctgaaccag ttacttgcaa gaaaccatag taaaatccta ttgtaaacac atattttggg
     3601 tctcctcctg ctgctatcag tgttgcattt tctgccatat atgtagctgc tattggcatc
     3661 catatacttg aagttattgc tgctccatga agcccaaaga accataataa ttgagttata
     3721 aatagtatta tagttactgc aaaaacatta tctacactgc ttatagctgg tgctaagaaa
     3781 ttcattataa tagctggtag tggttgacct gagacatttt tagttattgc tgctattgct
     3841 gtaaataaca ttatacatac tatcattgga gttaaatttc taaaactttt atttactaca
     3901 ctaggtactt cttttggaaa tctaattacg agatttttat cattcataaa cttagtaata
     3961 tcaactacta aaagtgctac taatatactt acaaataaac cttgtgcatc taaataactt
     4021 gtatctaata caccatctac tacttgtcca catacaacaa gttgtgcaac aactgctgtc
     4081 atgcctattt ctacatgatt aagattatat tttttagcta gtgcctgagc tataaaaaat
     4141 gctgaatata tagataataa actcatagta aatttattag ggataagtaa tgtatccata
     4201 ttttcagata ataatgtttt tgcacttcct tcaggtaaca tattgtttaa tgccataaat
     4261 aacatactta aagaaccaac aattattatt ggggtaatgc ttatcatacc ttcttttata
     4321 gcttgaagat gcctttgttt ttcaatcttt tgtgctattg gaagaagaaa tcttcttaaa
     4381 ttattttgaa gtgcttccat ttttattccc cccaattatc tatttttata taattcgatt
     4441 gccgacttca taacagaagg agcatccata cgaccataat gcttagtatc tattaaacca
     4501 actgctattt tgtaattctt acaagcttca actacatcat cttccttaaa cctaatttgt
     4561 ggtgctacaa gtactacatc tgtatcatta gcttcaatgt atgattttaa attttcaaat
     4621 gatgttgcct ctatatttat agttttagtt tttaactttt catgctcact acaaaaactt
     4681 ttcatctttt ccacaagtac acctgttgaa gctccatttg cacatactaa taaaatattc
     4741 ataattaccc tcctacaata tctaacctct tttattttct aattttttat cagccaattc
     4801 ttactctaat tcctatcagt ttttacttta attcttatta ttttatttta attcttatta
     4861 atatttactc taattcttag tactgccaat gattaaactt gaaagccgta tctataactt
     4921 cttcttgctt atatttttct aatattttta agtatctttc tttataatca ttatctactt
     4981 ctttttctgg tattactata ctagcttcat ttaaaaagtg gaatgaatcc cttcccattt
     5041 ctaatcctct atatgtatgc ttgtcaagtg ccacgtccat aacttctgga actttaccca
     5101 ttgcaaatcc ttttataatt atatttttta ataaatcact tgatctatct ttctcacatg
     5161 cacaaagata tcttattgca tgtatgaaaa ataaaggtct gtctccatct gcatatgaat
     5221 attcctttct tacttgattt aaattattta tgattattac agctgatgga tcccccattc
     5281 ctatatcttc aactgatatt gtaagtatcc ttctccatag cttatcttct aattctggtg
     5341 atgatatata tagttcataa gcaaattcac aagcttcttc caccatattt cttcttatag
     5401 ctttttgaaa tgacgatatt atttcgtctg cactaaatcc gtttcttgta gtcattcttg
     5461 cccatgggtc atttgccttt ttatctctta atattttatc ttgcatatta tttactcctt
     5521 tttatttaaa ttttaattat ttatattact catttaataa tataagcaag tattatgcca
     5581 gtttttttag acactttaaa acactgttat ttcaatcatt tttatcatca aaacttagat
     5641 actttgtcta agtatattta tatgtgtcta atattaatat tattttagac taaaaaaaaa
     5701 ttaccaaata agtttttata ctcattggta atctttttcg attatttctg catattctaa
     5761 tattaataat atttgatagc actctttttc attaatttct atattatatt ttttatctaa
     5821 ttgagatact atatctttta ttttgcttag actcttgtga taatcaagtg ttttttcttt
     5881 atcaagcttt tcaatttctc tagtatttcc aatcaaccca tctaccatga aagctaaatg
     5941 catcataagt ccaattactt tatcgtattt cttttctata ttaaatacta aaaacaattc
     6001 atcagacaca tattttatat ctttaaatat tctattataa ttagagcttt ttaaggatgt
     6061 ctttaaacct tcaactacat catcataacc tatacttatc tttataatat tttttaattt
     6121 attgatattt tcatccttat ctatatcttt tttgctaata tagtcaattc ctctaatatt
     6181 aattctttgt tcattgatta ctgcaacaat attactactt tctttaagtt tcgtaatatt
     6241 taaacttaaa tctttttctg ttttatatgg gacagatata atatctattc catctaagta
     6301 cctactcatc ttttcttcta atatttttct tgttttatta tctacacctt ctgaaacatg
     6361 tgatgctata ataattgttt tagacagatt ttctttattt tgaatttcat tagttccaaa
     6421 atagtgcttt ctcgtgttag tgatagagtt gtatacgtca tttaaaggta atcccatatt
     6481 ggccttctga actgcttcta acacagttaa tgtcgtcacc ataggaatta ctcttactcc
     6541 acactttttt tctttcttta taatttcatc aaaggagttt aatgaaccca tatctgtaaa
     6601 tagtaataca tctttattgt ctatattatt aattaaattt ttaaaatcta caataacttc
     6661 atcatagctt ttatctaact tcatatcgaa agaaatagca ctgcactttc caataatatc
     6721 accaactgct tttaccatac tacttgctgt agtttctcca tgcatagcaa ctataatatt
     6781 aatgttattc actattttat tttgttcatc ttgtttagct tgtactatga ataatgtaat
     6841 atatgctaca gtttctatag ataaaaataa atcaaattca ttttcaatta ttccaactat
     6901 ttttaatgct gttttaaatt cacttctgtt atttcttcta atttgattca aatctatgtt
     6961 gtttgtagag ctacttttat ccaatacgct ttttatataa attgccattg acttaaatat
     7021 tgattcactt atgtctattt cttcatcttc tttaataatt tgtcttattg attcacacat
     7081 gcttttaaac ttaacattat taaatagaga agcatctgct atattcattt ctacagattt
     7141 attaagatta gtatttactg cattaataat atttatatca ttgtagttaa taacttcttc
     7201 ttctcctaat gacgtaaata caaaatattc tattccatgt gttataactt catctgcttt
     7261 aatagacttc tctctataat catcactcac ttcatttata gatttatcaa aatatttttt
     7321 ctctatataa actggttctt tattatctct tttatatctt agatatccat ttgcaacagc
     7381 taattttata tcattttgaa gttgacctac attattttta caatcataaa gtaatagtga
     7441 tttaattatt tctttatgta cttttattga aatagaaata ctttttgatt cttccttgaa
     7501 aaaatttttg actaattcca ttctttcaat cattgtccta tctctcaatg atggtatttc
     7561 tattttcatt ggtattcttc tattgaatgt atctaatagt gttgatgtcg gattttctgt
     7621 agtagcacat attattaata ccttagactc tctttctttc gttgcatctc ctagtctttt
     7681 aaatgttccc ttatctataa aagtaaacaa catttcttga ccttctgctg gtagtctatg
     7741 aatttcatct aaaaatagta tccctccatt tgcaatttcc aaaagacctt ttctggaaga
     7801 ttctgcacct gtataagctc cttgttctac cccaaaaata tgtcccataa gtaattgtgc
     7861 attattagca taatcagcac aattaaatgt tacaaaagga gctttatttt ttctaattcc
     7921 actatctata gaataatcgt acatatatct agcaatcata ctctttccta ctcctgtttc
     7981 tccatagata atagtatgaa gtccatttgt aggatagagc attgcgacct tgcatttttc
     8041 tattataggt cttaaactat gttctttacc tattagtgtt tcaaaactat ctttttttat
     8101 tttgttttct acttttgttc ctttttttat gccaagcaac tcactttgtg tatcaagcaa
     8161 ttcattcttg ttaaggttaa gatttgcagg gatataatac acaggtcttc cttttatctt
     8221 cgtaaccata ccctcattga ataattggtt taaatatgta cttatattgt ttcttgcaat
     8281 tcctgtcttt tctgataatt ggttagctgt aatccctttt tcattttccc tatatgatga
     8341 ttctaaaact ttcattactt tatctttttt atatatcatt acaagctccc ctacattata
     8401 gtattttatt aactaaaacc cctatacaca ctttattttt taataaactc ttattcttta
     8461 actaaggtta taatttatca aactttcctt actttaaatt atagaaaatt attgtagaaa
     8521 aaataagatt attgctcatt ttttctacat tactattttt aattttatag tactttctta
     8581 acaacatact ttacttgttt ttaattttat tatatttgaa tttattatat ttgaaaagta
     8641 gaaataaaaa accctatttt ggagtagttt taaaatttct ccaaaaatag ggttttagtt
     8701 tgtatttcaa ataaatacct gttcaagtat ttttatacta aacaactttt aaattttgtt
     8761 gatatttatt tatttctgat ttagaagaat atacaaaatg tccatctgaa acctcaatcc
     8821 aacttaatga cttttcattt gaacaatcat atccattaga attatactct attctatttc
     8881 ttgacttagc atatctaggg tcaggaacag gaattgcaga aagtagtgat tttgtatatg
     8941 gatgaatagg attattatac aattcatttg aatctgccaa ttctactaat tttccattat
     9001 acataactcc tatacggtca ctaatatgtc tcaccataga taaatcatga gctataaata
     9061 aacaagttaa attcttttct tgttgcaatt ttttaaataa atttactatt tgtgcttgta
     9121 tagacacatc caaagaagct ataggctcat cagctattat aaattctggg tctactgaaa
     9181 gagctcgtgc tatgccaata cgctgtcttt gtccacctga aaaatcagat ggatacttat
     9241 ttgcataact tctatcaagt cctactagct ttagcatctc atatacttta ttcattctat
     9301 ctgttttatt tttacagata ccttgaattt ttagtggctc tgaaattata tctgcaattg
     9361 tcatacgtgg atttaatgat gaagtagaat cttgaaaaat aatctgcata cttttgttta
     9421 catctttttt tataaatttg tacgtttttt tatctgatat gcaatttcct ttgtaaatta
     9481 cttctccacc agtagattca tgtagtctta ttatagtttt accagttgta gattttcctg
     9541 aacccgactc tcctaccaat ccaaatatct cacccttata tatatcaaaa cttatatcat
     9601 caactgcttt tacagtagta cttttgtcca aatgaaaata ttgctttaag ttttttattt
     9661 ccagtatttt ttctctattc attagaaatc acccttccac aatttactct aactggtaca
     9721 tctacttcag gtgcatctgg gtgcaataac caagttgctg cactatgtgt atcattaatt
     9781 ttaaacattg gtggctcttt ttcataatct atcttaagtg catttttatt ccttattgca
     9841 aaagcatctc cttttggtgg gttcaataaa tttggaggca ttccaggtat attatataaa
     9901 tagtcatcct gcgaatctaa agtaggtaat gaacccaaca acccccaagt atatggatgt
     9961 ctagggtcat aaaatatatc ctctacagtt cctatttcta caatctttcc tgcatacata
    10021 actgctattc tatcagctat agttgcaact actcctaaat catgagttat aaatattatt
    10081 gacaaaccta ttttatgttg taaatccttt attaaatcaa ttatttgagc ttgtatagtt
    10141 acatctaaag cagttgtagg ttcatcagca atcaatacat ctggattaca agcaagtgct
    10201 atagctatta ctatacgttg tctcattcca cctgaaaaat gatgtggaaa ttgtttaaat
    10261 cttttctcag gattatcaat tccaaccaat tcaataagct ctatggctct cttttttgcc
    10321 tcacttttac ttataccttg atgaatgatt acagcttctg caatttgctt tcctattgat
    10381 atagttggat tgagagatgt catagggtct tgaaatatca ttgatatatt ctttcctctt
    10441 atatcttcca tctctttttc agacttctta accaaatcac ttgatttaag taaaacctct
    10501 ccatttttaa tatatccatt gtatgggagt atcctcatca aactcttaca cagtacagat
    10561 ttcccacaac cagattctcc aactatagcc aatgtctcac ctttttttag attaaaagat
    10621 acatttctta cagcctgaac ttctccttct tctactttaa aacttacaga tagattatta
    10681 acctccaata aatgttccaa aaaccatcaa cccctatgct attcaaacct tagggatata
    10741 tttttatccc taaggtttct aattaatttc agtattattc aattgtccag tcagctatgt
    10801 tccagaatac acctacacca tgatgaccta aaactgtatc aggtgttaat ccttttatgt
    10861 ttggttttcc aacatatatt gcatctatat aagcaataaa tgtataaggc atatccttag
    10921 tcatttctac ttggaattgt ttatataact ttaatttttc atctttatct tctgtttctc
    10981 ttgctttttg aagtatttta tctatagtag gattagagta agcactgtaa tttgcacctt
    11041 tatctgttcc aaatacttta tatgtatggt catctgggtc aaatggactt ccccaaccta
    11101 ttaaatgagc atcttgatta gcccaatctg tttcagttac aacaacagct ttagcatcaa
    11161 caccaatttc ttttaactgt tgtgcacata ttttagccat atcaactcta acttggtcac
    11221 tctcacctgc tgttatctcg aaagctaact tagtaccttc tttttcatag attccatcag
    11281 aacctaattt ccaacctagc ttttcaattt cttgtttagc tttttctgga ttatattcaa
    11341 acttttctat atcaggatta ttatatggtc ccatttgtaa aggtgaatat gctggtacac
    11401 catgtcctaa taatacactg tcaactattg cttttctatc tattgcatag cttaaagcat
    11461 ttggtaatcc tttagctttt ttatctttaa agaatttaga attaaaattg tataatatac
    11521 ctctatagtc ggctgttttc attatattta ctttaaaatt cttttcgtct ttttcaaagt
    11581 tagacatatc tttaggagtt atttgagcta ggtctaattc tcctgatttt aattgcattg
    11641 ccttagcctt atcatctgga acaatcttaa agactacttt atctaatcct ggttctttta
    11701 caaaataatc actattctta acaagtgtta tactttgacc tttgtcccat ttttcaagtt
    11761 taaatggtcc agtacctatt ggtttttgat taaattcatc agtagctata tccttaccct
    11821 ccaaagcatg ttttggtaat actcctactg ttaaataatc aagcattgct gtatttggag
    11881 cttttaaagt aatttttata gtattatcat taaccacatc aatttttgtt atatcttcat
    11941 aatttgatgc tatctcagaa gcattatctg gattcattat agtttctatt gtaaacttaa
    12001 catcatttgc tgtaaatttc tctccatcat gccacttaac atcatctctt aaattaaaag
    12061 tatatgtatt tgttgcctca tcaaatttcc agtcctttgc tagacaagga accaccttat
    12121 tattttcatc atgagctgtt aatccattaa atattaacga atttatttct ccatgttcat
    12181 atagtgcagg atttatactt gtatagtcat tacttccata aacaagcacc tttccatctt
    12241 taggcgtatc tgccttctta tctttgtctc ctccactaga acaacctgcc attagactaa
    12301 gtatcattac taaacttaaa acttttaact tctttaattt catgatgctc ccccttttgc
    12361 tttttataaa atatttttca aagctttgac cccatttatt taaatagata tttcaaatac
    12421 ctcagtattt gcttatttaa tactcaaatg ctgatttata aattactaga ttttttatta
    12481 ttattctttc ttatataatt acctatattt gttatacaca ccaatgtggt aaccaaaaat
    12541 atacccggaa tcagtataat ccaccatcta tttgaaagta atgcttcctc tgacaaagat
    12601 aacatacttc cccaagaaac aatttctatt ggtaaaccaa ttcctaaaaa gctaagtgtc
    12661 gattcagtac caatagctgc gcctatgttt gttacaacca tgaacattat tgatgccaca
    12721 aaatttggaa gtaaatgttg ctttaataca tagaagaatc ctcctcccat gctcttagct
    12781 gctagtatgt attcgctatt ttttatttgt ctaacttctg ttctcactat cttagatata
    12841 ttcatccaac ttgttatccc tattactatg gacatagata ctggatttga atttccaagt
    12901 atagcttgta caaatattat aattaatatt gaaggtatac taagtatgat ttctgtaaac
    12961 ctcatcattg catcatctac gagttcagat gccgaaccac ttatactacc ataaacaatt
    13021 cctataacag ttgatattac agtggaaaat agtcctataa ataaagatat ttttcctcca
    13081 taccatatca tagaatatat atctctaccc attgagtctg ttccaaataa aaaagtttta
    13141 tttggagcta aattagaact tgctaaatcc atgtatgttg gttcatgtgt cattataaaa
    13201 gatgagaata cacttccaat gactatgatt gataaaataa taattgatat atatggtaat
    13261 tctttaattt ttttagataa ggttttcttt gtttctatat gttcatcttc tgctactaaa
    13321 atataatttt ctcctacaat ttcaaaatca ctatattgtg gcttcattag tatcacctct
    13381 atcatatttc attctagggt ctattttatt gtttataatt tgagctaaca tattcccaaa
    13441 tactactaaa gcccctgtta ttaagcataa aactaataac atattataat catgatactt
    13501 tgcactttca aaacaaagtg ttcctaaccc aggataagaa aaaacttttt caactacata
    13561 agttcctcct agtatatgag gtatcgaaat ggccattata ctaatatatg atggcattat
    13621 atttctcagg caatgcttaa aaacaatagt tctattattt aaaccttttg ctttacataa
    13681 aagcacataa tcttctctta tttcctctag taatttattt cttatcatat atgtgtaata
    13741 ccatagatgg cttaatataa gtactgtaag aggtaagatt agatgtgata tcctacttaa
    13801 tatactggac tcttctccca ttgaataagc accactactt ggaagtatac ttaagtttat
    13861 actaaatata agtatgagta ctaaggcaac ccaaaatgat ggaatacagt tggttattgt
    13921 tcctaatttg catatgattc tatcaatgag cttatcttca tgtaatgtac aaaatattcc
    13981 taacaataag gctagcacaa aggtaagtat atatcctgaa ccacctaata ttatagtgtt
    14041 tatatagaca tcatttataa cagaagtaac attttgttta tatttaaatg aaattccaaa
    14101 ttcccctttt gatgcatttg aaatccattt tatatattga ctgtatattg gttcatccaa
    14161 accaagtttt ttcatagcat tttctttttc ttgtgtactc attctttcta ctccatcccc
    14221 atagtaagag attaatgggt ctcctggagc aagtcttgcc atgtaaaaaa caataaaaga
    14281 taataaaaac attactaaaa taaactgcaa caactttttc agtatatcct ttaacaaacc
    14341 ccaacccccc tttgttgcaa taaaaaaaac cacataaaag caaacgtaaa gtaacgttaa
    14401 aaccttcgtg gttccattat cattaaacaa aattaaattt tctatattta tctatgagtt
    14461 aattttagca tcatttatta actgtgtaaa caaacttttt aaaaattgtt aaaatttcat
    14521 caaattattt tatttatacc taaaataaaa tttttatatt ctattcttca ttattttcta
    14581 taaaattata aaattttagg ttgactatat aagaaaagta tattatatta gtttgtatgc
    14641 aaaccattta agaggtgatt ttattgaaaa gtaattatga ctgttttaga atagccatgc
    14701 tcttaaaaga actttattct aaaactatgt acacagtaga agaaaatttt aaagaaaatg
    14761 gattaacaca ccaacagatt atagttataa aactgatagc tcataatcaa gaacttacaa
    14821 tatcacaact atgtgatgaa atgtctttag ctaaaggtac ggtttcaggc ataatcagca
    14881 gattagaaca gattggatat atagaaaaat tcaagaaatc taatgataaa agaaatacat
    14941 acgttaagtt tacaacaaca ggatttgaat ttgccacaaa ttttaaaatt aaaatgcaag
    15001 aaagttttga tgatattttt aaaaattgtg atgaaaacga attgagtgac ttagtaaaaa
    15061 atcttagaaa tatattggca aaagtaaagg agagataatt atgaattata aattaatact
    15121 tgcaatagta tttataacat cagctttaat tttctacact ataggtgtat ttggagaaag
    15181 aaaggcaaaa attttaaaaa agaaacatgt aattatattt tggcttggtt ttatatttga
    15241 tactttagga acatttacaa tgagtaacat agccaacagc catacttttg aagtaaaatc
    15301 tgctttatca caaaaccttc atagtattac aggtcttctt gcaattgtgc ttatgctttt
    15361 tcatgcaagt tgggctactt ttgtcctata caaagatgat gaggaaaaga aaaaattctt
    15421 tcataagttt agtatagttg tatggactat atggttagtt ccatatttta taggtatgtt
    15481 tattggtatg gctggatagt aaaataaaaa gtgtgtaaga aatactgtag gtaaatttgt
    15541 ataagacaaa tttatctaca tccttctttc acacttttac atatttattt ataatactcc
    15601 attatttctt tcatgtttct taatacctat atagaatatt taattatttc tatagtattt
    15661 tattattttc tcacactttt tcatatatat attgttttac tatttcttca tatgtatata
    15721 tgaaatattc cattatttct ataaatgttt tattatcttt ctcatacttt ttcatatata
    15781 tattgcttca ctattttttc ttatttcttc atatacatat gaaatatttc attatttcta
    15841 taatgtttta ttatctttct catacttttt catatatatt gcttcactat tttttttact
    15901 tctttattaa atacttatgt ataacataca tttaataaac gctaactatt aaacacctaa
    15961 tacttgagtt actcctggaa cttcactcac caaaacattt tcaataatag ctttgattgt
    16021 catagtcgct cctggacacc cactacatgc cccttgtagt ctaactaaaa ccacaccatt
    16081 ttcatttaca tctataagct ctacatctcc accatctctt tgtaatactg gttttatctt
    16141 ttcctcaagc actttttcaa ctttttctct catagctatt ccccccagaa atattttatt
    16201 agcaaaatta taccaatggt ttaaattttt gtccatctaa tgatttatca aattcaattt
    16261 ttgcttcatc aataatttta gtatccataa atacatcata agcactacaa gccagtactt
    16321 tagctgaatt tatcatagca gaaaatccta tatttgaacc tgctgatgaa catgactgcc
    16381 atgtatgact tgcaattcca acaggccaag ctgccattgc aaattgagcc actggtatta
    16441 cataacttac atctccaaca tcagtagaac cagctagtcc tttatctttg tcaccgtcaa
    16501 ctatttcctt gtgtatatag ctttctacaa tagatttatc attttgtaat gatgttgcta
    16561 cacctaatct ttcttctcta gtaagagtat cacacaactt ttttgcaaat tcttcttctt
    16621 caggagtatt tttagggcaa ccaacaaaaa ccatattgtc ataaactaaa tcagtcaaac
    16681 attggtttgg tatatagtca tatattccat ctgtaacctt atactccatt tcagtttctg
    16741 tcatcattgc tgctccttga gctactttta ttaatctatc aagaacgtgt tctgcatcct
    16801 ttgctttttt acctctaata aagtaccaac tttcagcaaa tccaggaact acattaggtc
    16861 ttccaccacc attagttata acatagtgca ttcttataga gtcaataaca tgttctctca
    16921 aataattagc tccaacattc ataatttcaa cagcatcaag tgcgcttcta ccattatgag
    16981 gagcttgagc tgcatgggct gttatccctt taaatttaaa ttttacagat aagtttgcca
    17041 gacttccacc tctccaaggt gcatttatat caaaaggatg ccatgtaaat gcacaatcta
    17101 catcatcaaa acagccattt atacacatag ctgtctttcc tccaccttct tcttcagcag
    17161 gacaaccaaa atattttatt gttccattaa atttattttc ttctattaat ttttttatag
    17221 aaacaactgc tcctacacct gctacaccca acaggttgtg cccacatcca tgtccagctt
    17281 ttccttctac caatggcttt ctttctgcac ttacacattg tgatagctct ggtaaagcat
    17341 catattctcc aagtatgcca atcacaggtt taccctctcc aaaacttgct ataaatccag
    17401 taggtaaatt ttctacttct tcaattttaa atccttttga ctttaggtat tctttttgaa
    17461 tgctacttgc atacttttct tcaaaggcta attctggatt ttcccatatt ttcttagata
    17521 aatcaattaa ttcttctctt atttcttcaa cattatttat gatatactct ttcataattt
    17581 tcctccaaat atatgtattt ttgatatgct ttacagatta tattatatac taacattcta
    17641 tttattcaca attttttgtt aattaatttt attcatatgc tcttctatgg agtatatctt
    17701 atcttcactt tgcctcttca taaatttaat gtactctatc ttccataaag tagtttcagt
    17761 tttctcattt aacataaatt ctaatatatt aatttctctc attctaatat cttcataaaa
    17821 tactacacta cccaatattg ccaattctaa ttcacttaat gatgcaaaca acattaaata
    17881 ctcttctcca aataaacatt cagattcaag aatatcgata aagtcttttt tagcattgat
    17941 attttccttt attattctta ttttttcaat tatagatgta ctatctaata tctcattgaa
    18001 tatctctcta aacgattcat catccaattt actttcatca tcaacaatat aatcttctaa
    18061 gtgttccttt ttatttttac tcacagttac catactttta aaagtgttac tttttattga
    18121 gcttagcaca gattcaataa atatcttttc atatttttta atatatctta ttacatcttc
    18181 atcttctatg cttaatcttt ttattaatac ttcaattgct tccataagta gtaaagttat
    18241 ttttttattt attctaattt ctctgttaat ttcttcaaaa tcattataat ccaaattact
    18301 atctacttca gtgttaaaac tatcatctac ttcaatcaat tcaattatat tactttcttc
    18361 agagtctata actttatctt cagtaatatt attgtacata tttttaaatt gtttttctaa
    18421 aaattcatac tcatattttg aaatttctaa attagtcact tcatttccta aaatagtaga
    18481 aaaaatacaa ttatttataa taagttcaaa taaatttaca agtatagcat cacaatctat
    18541 tttataagtc accccatagt cataaaataa tttttctcta tcttttttct taaataggtt
    18601 acaaaatcta ttttctatat ctatactctc aatataattc ttcacataat aaataccctt
    18661 aacatccata tcatctagtg ccaatggata atctatactt actggaacgt cctgagcttc
    18721 aaattttaca atataacttt taaagaaact tgataactcc atcaaggtat cattatatgc
    18781 tattgaatta gtatccaatt ttctactcat cattagttta taaaaatctt ttagcctaac
    18841 taactcttcc tctaatattt caatgcctcc aaggtacact tttttaacat tcttagcagt
    18901 caactccaca actctttttt ctatatcccc aagcttattt atatatgcat caatagcata
    18961 ccatattgaa atcaacagtt tttcggcaac ttctgttttt actgatgtgc tttgaccatt
    19021 tgtatatttt ttaatcaaat ccataagtat tagagatatt tcttgttgta tattatatac
    19081 ttctctttca tctatcactt tacaatttag acattcctta agtagagata tggaatattg
    19141 gttctttatt aaattatttt cgtttatatt aatattactt aaattattta acatacaaaa
    19201 tctctcctat catatattaa acttctccaa atttaaattt ctttgcaaat tcgtctgctt
    19261 ctcctcttac attgtccata ttgcctgaaa atttttcata aaattcaccc agtatttcta
    19321 taatctcatc atcacatatc ttgtcatcag tttcattttt taaataataa aaaatttctt
    19381 gcatatcatt aatagcctct aaataattgt ccacatttgt atattgtgat gtatatatat
    19441 tttctattaa ctgttttgta acttttatat ctaattctat tcttccatac ccctttaaag
    19501 tattatctct cgaatttatt atatctttta catcagattc agaaagagct agaccataat
    19561 ctccagattc tatattagtt tcaagcagtt catttctttc tatttccttt aaattctgat
    19621 ttatagaact caaaataata ggtgatatca tttttaaatt ctcctttttt attttttcca
    19681 ttgacttttt ttgtttttta tgctatactt aaattaattt atattatttt accaaccact
    19741 tataatagta gtgttaaaag tggtttttgt caactcaaaa ttactatctc aattaaactt
    19801 ttcaattttc tcaacaaaaa aataccatca tttagatata taactttcta taacaacttt
    19861 taattcagta gttatttact aaaatctaaa caatgatata tttattaatt ttatttatct
    19921 tttttggctc tacttctact tttctttaca tttgagcaat ttctacaaga aggtgaacag
    19981 tattgagatt tagaatttgt aggaatataa attttaccac agtacttgca tttatttaaa
    20041 gaagaaggtt cacttgtaat tgcaaaggca tagatagtct caatagctgt tttcaaagaa
    20101 tcaaactccc atgcaataat tggtttatct aattggctta tagaaaatcc tatcttttga
    20161 ggattaaacc ctccagacat aatagtaaca ctttcagtta atagattaga tgtattttta
    20221 tatacacaaa tttgattaaa atgcttacac atatctttag caaaacttac aatccaatct
    20281 agttgttcag tgtagaactt tgaaaatact aaatctaaaa tcaatggtct ctttccaaaa
    20341 aactttggag attcttctct ctttgataca tctatacccc ttctatactt tttaaaatac
    20401 acatcttcat cacttgcaaa tggtataaac atgtttacat attcatctgt actcaatata
    20461 ttctcttttg taatataatt cttttcaatc atcagtactc tttcttctcc aactatatct
    20521 ctattatata cacttgaata tattaaaccc aataatccat acttttttac aaattcaagt
    20581 acttctttct ttagtttcat ttcttttgtc tcttttgata tatcttgtaa tgcctcttgt
    20641 cctatgcgaa ttatatctac tattatatca tctgctacat caaatgggtt atacatggta
    20701 aacacagcat cttctgttgg aactatatat aattcatctt cttcagtaat tttatattca
    20761 taatcactat acctaatcca atcacttgca aaattcccta ttaattctat ttttttattc
    20821 ataataatca ttcacacctt tcaatgtaat atataatttc atattactat tacactttta
    20881 gtttattcca tattttctac actgtcaact attcttttta tatttttagc atattaaaat
    20941 ttataatagc ctttataatg gatttctaga gctaaatttc ttgtttattg atgactaatt
    21001 cataattaaa tttataaaaa ctatttacat ataaaattaa tctctttata attgatatgt
    21061 aatatatttt tacacttaca tattacatat caattataaa gagaggtatc taaaatcatg
    21121 gatagaaaac gtgaattaaa acaattatac aaagaaatga aatttgacac aggtgtattc
    21181 ataataaaaa atgatattac taaaaagatt taccttggaa aaagtaatga cataaaaagc
    21241 aaatttaact ctctcaaatt tcagcttggt gctggctcat gtatgataaa agaattaaat
    21301 aatgaatgga aaaaatatgg tgaaaaagca tttacatttg aagttttaga acttataaaa
    21361 catgatgata acaaaacaga gaaagattat ttagaagaac tagatatttt agagatggtt
    21421 tggttagaaa aattaaagga agataatact tatgaaattt attccatata aaaaatcata
    21481 taatataaga aaaggagata gtatatcaaa atagacattt agttcataag atactttttt
    21541 atataaaata aagtatcttt tcataatttt aacaatgaaa aagaggctta tctccatttg
    21601 atagcctctt cccatatatt ttataccatt ataaaatgaa caatctacta attttcaatg
    21661 tgtatattca ttttactaat aacactccat tacttcttta cagcatccaa acattgctct
    21721 ataatactct tatcacttat acctattgct gttactttac tagctccact taatatactc
    21781 ttatcacttt tatttgaaac taaaacaaca ggagcatttt ttgcaagtgg tgatgcaact
    21841 aaagcataaa ctaaatcgtc tccacttgtt atatagaact cttttgctcc attatagaac
    21901 ttttcaataa catttttatt agtttgatat ctatcaacac caccaattct agttgctcta
    21961 tatctgctca ctatgtaatc acttaatgta gactctcctc caatagcata tactggaaca
    22021 ggagaaactc caaaccatgg gtctaagtct gtgtcttctt ctgctgaagg tatatctttt
    22081 gtcaatatta taggagctcc atctctataa gcaacagatg caacacttac tgcatcagct
    22141 tcatccttaa atccatttac taaaaacatc ttatcactgt ttttaatttt ttctatttca
    22201 cctgcaattt tataacttgt atctactcta tctacaccat caattcttat aacttgcatt
    22261 cttctcataa gtaacatttt ttctacatct ttacttatag aattttctcc acctattaca
    22321 tatatcttag taactctatt cagtctttga agcgttgctt ctggtatatc atccttatta
    22381 gttaataaaa tagctgcatt atttactcct gcaagaccac ttgcagcaat cccatctacc
    22441 attgtagaat ctgcattgat aagaactgct gttgtaaaat cttgcttatc tgaaataagc
    22501 ccagctgttt catatttatc tactccttga atattttcaa tcttatctag tgcgtttatt
    22561 gatgttggaa aactaacact taacagtaat gctgaaatac ctaacgccaa taccttttta
    22621 ctaatcctca taaattacct ccctaaaaca aatatattta gtattagtat aatataaaat
    22681 catttaaaaa tagtgtaaaa atagttacac ttttttataa tttaaataat tttagattaa
    22741 acacaattca tccattaaaa taacttcatt tattctatat gctaagccat cccacgtttt
    22801 ttttgacata tctacagatg ttttcttatt tgagttattc aataaagatt gtatcttaga
    22861 atctattgca ttatacaaat tattttcaaa atcatataac tcttcatctt ttggaatacc
    22921 ttctttctcc ataaaaggta gagaaacata ttctatcttt ccagaattat taatctcact
    22981 accaatccac tctttaacac caagaatatc agtagtgatt acatctgtgc cacaagataa
    23041 agcttctaaa actacaactg gtaatccctc ataaaatgat ggtaacacaa atatttgtga
    23101 cctgttgaat agctcagcta aatctctctg ttctaacttt cctaggaaat tcattttaaa
    23161 tggagactta cttgccagtt taactatctc attatatgat tcgatatcgc ttccagtacc
    23221 tgcaaaattg acttctatta aatctttact atattttaat ttagatatag cttttataaa
    23281 tggaatcagt ccctttgatt tacatatctt acctgcaaat actattttta ttttatcatc
    23341 ctttatttta taatttttat tataaaatat atcatcatta taaccactac caattacaac
    23401 tactttactt tgacttactc caaaagtctt tataatatca tatttctgat tttcatgaag
    23461 agcaaatatt aaatctaatt tccttatatt tgctattatg tattctttct ctaaatcaat
    23521 ggtatttaac tgtcttaaac aagttccatg acaaatagac ataaccttta tatcttttac
    23581 catttcccta acaaatgcag ttaaaaggta caaatgatga catattataa gttctggttt
    23641 aaaatcattc atagccttat ctatatttac tttaaattga tatttcaatc tatttatcat
    23701 gtctatattt aaatctttat atcttgtact ttcatatggc atagaatcac tcatacctac
    23761 aacaggaaaa tttaactccc cacaattata ctttactgga taaaaactta cttcacttgg
    23821 aaaacaattt acatcatcat ttacatctat acctgcaatt acagcttgct tatgaccgat
    23881 tttttcgaat ccttttatca taccagacaa atatatacca ctacctgtac tatttggttt
    23941 ttgtgttatt atatgaagaa ttttcacttt tcacttgcct cctttctaaa attaaatagt
    24001 tttatacagt ctaatcatta tatatatcta aatataaaca agatgaatca tcttttactt
    24061 taaatcttgg cactttaacc gctttatagt cattatcttc aaaatccctt actttattat
    24121 gtatatatcc tataccaaat ttttctgcta tacgtatcaa ttcttcttct tttattagat
    24181 tatatctatc acatgcactt gtaaaaccat cactcgttag catcaattga aaatcttttt
    24241 ttatttcaat gtatccatat atagaatttt ccacagcttc ctcatcaaaa tccaatatcc
    24301 aatagccctc ttttgtattt ttcttcaatc tattgcttac tattgtatcc ataacactag
    24361 ttctaatctc atcaaatgcc atctcttcca agttagaaag tttactcatt tcatcaaata
    24421 cagtattatc aaatttacaa atactcctat cttttataac tttggaatct ccatttttaa
    24481 taaacaaagc acaatctcct aataaaaaat actctacttt attttcatga aattttacaa
    24541 caactataga actagatggt aaatctaatt tttcaacctt aaacccattt aatcttagtt
    24601 catactcttt ttttacttct attattccag tattaataat actctttaat gattcttctt
    24661 tatttatatt tttatataaa tacctattcc accactgaac ataccacctt gcgtcacttt
    24721 cagttgacac taaatttttt ccattaagtc ctgtagcacc atctaaaacc catgccccaa
    24781 atggatttat accgactaca tcttcattaa atttagctgt tccttgatta cataataggc
    24841 tatagtttct tatatttaaa gccatatcaa cctccaaatt gaatatctaa aaataaagtt
    24901 ctatttaaaa ttatacagca aataaaaaaa tctacaacaa aacttgttgt agatttttac
    24961 ttaatctata ttatctttat actttcagta ttttaatgat ggaataatct attcttagta
    25021 aatgccatga ctatgttata cttattacaa gttaatataa cattatcatc acgaatagaa
    25081 ccacctggtt gtgctataaa acttacccca cttctttttg cacgttctat attatctcca
    25141 aatgggaaaa atgcatctga accaagtgct actcctgtta aagttttaag ccatgctctt
    25201 tttccttctc cagttagagg ctctggtttt tcttcaaaaa agttttgcca tatgccatca
    25261 gcaagcacat ccatataatc atcagaaaga tatacatcaa tagtgttatc tctatctgga
    25321 cgacctatat cctttttaaa ttttaagttt aatactttag gatgttgacg aagataccaa
    25381 gtatcagctt tgttacctgc aagtctagta caatgaatac gtgattgttg acctgcacct
    25441 acccctatta cttgtccatc tttagcataa caaacagaat ttgattgtgt atattttaat
    25501 gtaataagag ctataattaa atcacgtttt gcactatctg taaaaatttt attatcagtt
    25561 ggaatatctt ttaataggtc ttcatttatt aatatttcat ttctaccttg ttcaaaagta
    25621 attccataaa catcctttgt ttcaataggt tcaggagtat aattttcatc tatttttaca
    25681 atattatagt tgcctttacg ctttcctttt aatatttcaa gggcttcatc tgtatatcct
    25741 ggagctatta taccatcaga aacctctctt gctataatag ttgcagtctc cttatcacat
    25801 acatctgaaa gtgctataaa atcgccataa gaagacattc tatctgctcc tcttgccatt
    25861 gcataagcac aagctaatgg agaaagctct aaatcatcaa caaaatatat ttgctttaaa
    25921 gtatctgata aaggtacccc tactgctgct cctgctggac ttacatgttt aaatgaagtt
    25981 gctgctggaa gacctgtagc ttcttttaat tccttcacaa gttgccaact attaaatgca
    26041 tctaaaaaat ttatgtatcc aggttttcca tttaatacct ctataggaag ttctccattc
    26101 ttcatataaa tctttgatgg tttttgattt ggattacagc catactttaa ttctagttct
    26161 cttgccatat actcatccct ctctataata aattaatcat aagtttgatt aatcctatat
    26221 taattaaatt attcgtacta ataaaattat atggcatatt tatccattaa tcaactatat
    26281 tttttaaaac tcctattcct tcgactttac attcaactat atcgccatgc tttaaatata
    26341 cttgaggatt catccccata gcaacccctg ctggagttcc agttgaaatt atatctcctg
    26401 gctttagagt cattcctctt gataaatcat ttattatagt aggtatatca aatataaagt
    26461 actctgtatt agaatcttgt cttacttctc catttactac actacttata tctaatttta
    26521 aaggatgttc aaattcttct ttatgtacta tacaaggtcc catagatgta tgtgtgtcta
    26581 agctttttcc tctaaaccat tgaacatgtt tatcttgaag tgctctttca cttatatcat
    26641 ttactattgt atatccaaat atatattcat aagcatcttc ttttgatata tttatacctt
    26701 ctttacctat gattactgca agttctgatt catagtccaa cttctctacc aaatctccat
    26761 gtaagcttat cttatcatcc actccaatta ttttgtctgc tctcttagaa aaataaattg
    26821 gataatctgg cataactacg ttttttataa ctccatctgg gatttcattg acatggtctt
    26881 tatagtttag acctaaacat ataatatctt ttttaggtct tacaattggg gaacataatt
    26941 taacttcttc taacttataa cactttgcgt tttcaaatga attgtttttt attttttcta
    27001 aatctcctgt agatacgttt tcaataaaat cattcatatc agtatataat ttacttaatc
    27061 ctaaactatt aatttcatat atactatttg tttctgaatt aaatacacct attttttctt
    27121 cattgctact acaaaaagtc acaaatttca tttttattcc tccattcaat aagttgatta
    27181 atattattta atttttatta gtttatataa attgtaattc ataatattta tatgtcaata
    27241 catatttata tattttaaaa atattcaaat aatttttatt aaatttatta gttattaata
    27301 tataagtgct ttataaaaca caaataaaat aaggttgatt taaaattaaa tttaaaacaa
    27361 ccttataaac cgattatact atctacctaa taaatatagc aaataagctc ctcaataata
    27421 tacaaaaccc tacatctcta aacctatact taactaatcc aagtacaata ccaaaaacag
    27481 tacctatcat aatttttgaa ataataactt caaaggtgta gcttgaattg ttatacaata
    27541 ttacataatt tcttataaca tctatgtatc ctatattata aattccagat agtatagatg
    27601 ttatacagat aattttactc tttgacttta taaaattact tagatagttc catatatatt
    27661 ctctaaaaaa taactcttca aatattggga ctatcaatac agacaaagtc atcatagtta
    27721 cattaaaaag tacatatccc ttagtacaat aagttacaat tattgctaaa gataaaacca
    27781 caacaaaaag tatcagctta cacttttcaa taagtatatt gtttttattt tcttcaaaag
    27841 cttctgtgat ttttctattt ctaaccttgt tatacaaaga attatctttt aaaaataaaa
    27901 ttaacgataa accaactaat gtaaaagaaa ttaagtttat aatattaaaa ttttcaagag
    27961 taaattcaaa ttgacttaga agtacataat tcaaaatcat ccttaatatt tgaactataa
    28021 acatcaataa aatagaatct attatgcatt ttttgtaact atacttcatc ccaatttaaa
    28081 tcaccccatg tatatgctaa tcgtaaagtc catttaatac cctacttaca gttgctttgc
    28141 tccaacttgt ttgatttgaa atttctttat agcttaagcc atctcttctt aaactcttta
    28201 tattatttat atcatcatca gtaatttgtt tttcttttgg cttaaggcta tttttatagc
    28261 ttcttagtct atccaattct gatttcaaac tatctacctc aaactgtttt ttttgaagtt
    28321 tactctcata agaatctctc atttcattaa actctttaat gtagtttact ttccagtcct
    28381 catccatttt tgttttaaat atacccatac tttaacctcc ttaaattttg ttactcaagt
    28441 tatgtatcga ttataaacat taatttctat atttatcttt aaaatccttg tacataaccc
    28501 ctagataagt tagtaaaatt cagatatatt tttacaattt taagtatata ttaacaatag
    28561 aaaaaaatat aatgtcttaa tacaacatat tatatactaa aagttgttaa aatgaacctt
    28621 tttatagtct aaatcagagt caccgtatgc tttcttttct tcatcaggat atcctataga
    28681 aattatacat tctacactgt acttgctagg tacttttaat tcttctctaa tgtacttatc
    28741 agcttctata ttatcatcat gcattctatt tcttacttgt atccaacaag aacctaaacc
    28801 tagttcatga gcttgaagtt gtatgtatga agcagctata cttgcatcct ctatccaaac
    28861 atcatttttt tctttatctg caataattac aatagctaaa ggtgcatttt ttaagaaaaa
    28921 tccaccacct ttagttctac attgagataa attaattagc ttttctttat catctaccac
    28981 tataaattcc catgttctaa gcccctttga tgatggagct aaaagagcag cttttaatat
    29041 tttatctaat ttttcttttt ctacttcaac atccttgtat tttctaatac ttcttctttt
    29101 ctttagaaat ccaatcatat aaatcatccc tttcataata gcatacacta ggttatatta
    29161 tgcccttact aatgctgaaa atctattatt tatcccttgt attataaatg ctctttataa
    29221 tattttatca taacagtaga aagatttctc ctttcctaaa aaactcattt ctccgatttt
    29281 tataaaacca cactttgtaa gtaataaatt catttttgag tttattgaat atgtatcgct
    29341 ctttaagtat gatacattgt tttctacagc taatttttca gcaaaatcaa ctaacttaga
    29401 tgctattcct gtctttctaa agtttggatt tacagccatt ctatgtatta ccattgcttt
    29461 tttattagat gaccaattta agcctaaata ttcttctggc tcttcataat taagacatat
    29521 aaaccctgct acttctccat ccacttcata aatatataaa tcttgtttct taatatctga
    29581 aacaaagtct ttttctaatg gatagttttc atcccattgt gtattattat aagtcttcat
    29641 ttcttccact gtagatttta taatttgcat aatgctttct aaatcattca tattcgcttt
    29701 tctaatcata aaaatatctc cttaagttaa tgtatttatt tactatctct ttactttaaa
    29761 ccattcattt tctacgtttt tgctcatttt ttctaataac ttagttacca cttgtttttc
    29821 ttcatctgta aaattatcaa aacatatctc tatacttcta ttctcttctt caattatcaa
    29881 ctcataaact tccaaagatt tatcagttgg agttaaatta tatcctcttt tatcaaactt
    29941 atcctgcttt ttatctacat atcctgcctt tattaatttt tgtatagcct tggttgttgt
    30001 agccttgtct acctttaaca tatttgataa ttccacaaga tttataccag gattttcaca
    30061 gattcttgtc aaaaatgtaa attgtccttt ttgtaacttt aattccttgt acttaatatc
    30121 atttattgaa tttactgctc tagataaagt acctacttct cttaatatat tactatctaa
    30181 agtcttaatc aaacacacct ccactgaaac tactatggct aaagtcaaat agtttctgtt
    30241 ttataaaatt tcacataatc aatatattca tttttagttg aaagttcaac ttttttaaat
    30301 tttaccatat tttggttgaa agttcaatta aaaataataa atttatttaa tctttctttg
    30361 catattaatc aattaatttt aaaattaaaa tggatatccc aaaattaact ttttcgttta
    30421 tgaggaactc tcttttgtat aaaatcaaat atattttatc attccaataa aaaaggctta
    30481 tctctatttt gagaaagcct ctttccttca atctatattt tactttttcc ctaaataaaa
    30541 tctatacaat atacttacac acctcatccg caaactctgt agtagaagct gagccaccca
    30601 aatctacagt caatttactt ccttcaagaa atactttttc taaagctgtt tctatttttt
    30661 gtgcattttc atattcacct aagtatctaa gcatcattac tgatgattga ataagtgctg
    30721 ttggattagc cttattttga cctgctattt gtggagcact tccatgaaca gcttcaaata
    30781 tcgcacaatc tttaccaata tttgcacttg gaattatacc taaacctcca acaagcccag
    30841 cacctaaatc tgatagtata tctccataaa gatttggcat taccattaca tcataatttt
    30901 ctggatttaa aactaagttc atagctgctg catctacaat caaatcatca tattctacac
    30961 catgttttga tgcaacttct ctaaacacat ctaaaaacaa tccatcagac attttcatta
    31021 tatttgcctt atgtatagct gtaacttttt ttctcttatt atctttaaca tagttacatg
    31081 caaaatcaac gattctttca cttgcacttc ttgttattat ctttatactt tcagctgcat
    31141 aatcacctat tttatgttct attccagcat ataaatcttc tgtattttct cttacaacca
    31201 ctaaatcaac atcttcatat cttgatttta tccccttaaa acttttaata ggtcttaaat
    31261 tgacatacaa atctaatgcc tgtcttaaag ttacatttac actcctaaat cctttaccta
    31321 caggagtagt aattgggcct tttatagcta ttttgttctt ttttatacta tctataatat
    31381 attcaggaag tggagtacca tactcttcaa taactgcctc tcctgcatta acttcttccc
    31441 attctatttc tactccagta gcttctacta cctttttcat agctttcgca acttctggtc
    31501 ctattccatc tcctggtata agtgtcactt tatacattca atattccctc ttttcatatt
    31561 aattagcttg atttttagtg tagtttaatt ttccaccagc ttttaataca tcaacttctt
    31621 ttgctgacaa ttctactttg accttaaaag aagttccttt agttgtattc ttaacttcta
    31681 aaattccact acctagattg tctaaaatat ttggtatctc cagattatct aaaagagata
    31741 tattttcata atctttctca tcacaaaact ccattggaat tataccacta tttatcaagt
    31801 tagccttgtg gattcttgca aagctcttaa ctattacccc tttaacacct agatataatg
    31861 gtgctaaagc tgcatgttct ctacttgaac cttgaccata attatctcca ccaactataa
    31921 atccaccatt attgtctttt gctctctgag gaaattctgt atctacagta ttgaaacaat
    31981 agtttgcaag atacggtata ttacttctaa aaggaagtaa cttagcattt gatggcatta
    32041 tatggtcagt agttatatta tcttctgtct ttaatataac ttttccacct atagactgac
    32101 ttagctctgt attaagaggg aaaggtttta tattaggtcc tctaactact tctacatcac
    32161 ttcctacatc agcaggttta attatcatgc tatcatctat caaaaattca tttacatcta
    32221 aatttgtaaa tttaatatca aattctcttg ggtctgtaag cactcccttg attgcactta
    32281 ctgctgccac ttctggactt actaaatata cttgtgctga caaagtccca cttctaccat
    32341 agaaatttct attgaaagtt cttaaagaca cagagtcagt acctggagat tgacccatac
    32401 caatacatgg accacaagaa ttttctagta ttctagctcc agcacttatt atatctgcca
    32461 aagccccatt tctagcaatc atctccataa cttgtcttga acctggtgct attaccaaac
    32521 tcacatcctt atgtacttta tttcctttca ggatttgtgc tactttcatt aagtcttcat
    32581 aagaagaatt tgtacaactt cctattgcca cttggtctat tttaatcttg cctatatttt
    32641 caacttcatc tacattgtct gggctatgag gttttgcagc taatggtttt aattcatcca
    32701 agtttatagt aatctcttca tcataaactg catctgcatc tggttttagc tctatccatg
    32761 cctcttctct tccttgactc ttaaaaaatt ctagtgtttt ttcatcactt gggaagattg
    32821 aagtagttgc tccaagttca gcccccatat ttgttattgt agctctttgt ggaacagata
    32881 ggcttttgac accttctcca ccatattcat aaactttacc tactccacct tttacagttt
    32941 gttttcttaa cacttctaat attatatctt ttgatgatac catattattt aattttccaa
    33001 ctagattcac cttacagact tttggtgctt ttatatagta tgctcctcct gccatggcta
    33061 aagcaacatc taatccacca gctccaatag ccatcatgcc cacacctcca gcagtaggtg
    33121 tgtggctatc agaacctaaa agtgtatctc ctggtgttga aaatctttct aaaaatactt
    33181 gatgacaaat accatttcct ggcttagaga aataaactcc atatttatct gccactgttt
    33241 gtatatactt atggtcgtct gcattttcaa atccttgttg taacatatta tggtctacaa
    33301 atgccacact tcttttagtc tttactttat ctattcccat agcttctagt tgaagatatg
    33361 tcattgttcc agtagaatct tgtgttaaag tttggtctat ttttatacca attgaacttc
    33421 cagcaacagc ttctccatct actatatgtt ttttaattat tttataaact atattatctc
    33481 ccatattttc ctcctaaaca attatatctt aaatatatga acctctaact gcttcttctt
    33541 ctgttgtgcc tttctcatgt gctagtatat cacaatataa ttgaagaatt tctttatcca
    33601 ttaaacttct ttttaatctt atagatgtag ctcttatagc atttaatagc ttggtagcgt
    33661 tttctggaga aatatacatt tcatattcac tcaacttatt tacaactgca gctcttcctg
    33721 aatgtttacc tattactatt tttctttcaa gatttacttc acttgggtca aatggttcat
    33781 agttatgtgg gtcttttaaa gctccatctg catgtatacc agattcatgt ataaacatat
    33841 tatccccaac tactggtttc catgtaggaa gtattcttcc tgatgcctgt gctacatact
    33901 cacatattcc tctaaatttt ctagtatcta tattatttaa atcacattta taaacacact
    33961 taagtgccat taaaacttct tctaatgctg catttcctgc tctttcacct aatccattta
    34021 ctgtaacacc aacataattt gctcctgctg ctattcctgc aagtgcattt gcagttgcca
    34081 tcccaaagtc attatgtgta tgcatttcta tatcaaaatt agttctttca taaagagttt
    34141 ctattgcatt ctttatagaa aaaggattca taactcctac tgtatcacag tatctaaatc
    34201 tatctgcccc tgcttgtttt ccaacattta taaattcagt taagaagtct atatctgctc
    34261 ttgaagcatc ttctccattt actgaaacat ataatccatt tttctttgca aattcaactg
    34321 ttttagccat attttctaaa acccagcctc tagaagttct caatttattt tctatatgaa
    34381 tgtcagatac tgatattgat atagctactg catcaacacc acaagaaata gattcttcaa
    34441 catcttttat tactgctcta ttccaagcca ttatatctga ttttaaattt ctactacata
    34501 tgtgctttat tacatttttt tcatctccac ccatagtagg tataccaact tcaatttggt
    34561 caacacctag gtcacttaac atttcagcaa tcattatttt ttctctattt gcaaatacaa
    34621 ccccagctgt ttgctctcca tctcttaaag tagtatctac tatttttatt tcctttgctc
    34681 tatcttttga tataacgcac atattaatgc cccccttagt atacttttaa ttttaaaaca
    34741 ttaagtctta tttttcattg atacctctaa cttatgatta tttttttatt ttttattcat
    34801 tttaatttca tttgcaattt atttttttag cttttcatat cttgtaatct attatattac
    34861 tttgtatcat ttattgcact atattttttc ttttttgtga aaacttctta aaaatgaaag
    34921 ttattatgtt tttcttgcat tttaatttaa tttttaaata gatttatttt caaaaaacct
    34981 ttaaaaataa acctataaaa ttcctactaa aatttaattt aagttacatt ccattttaaa
    35041 gtatcttaat atatttttaa gctatataaa taataattaa aaaatttact aaaaatactt
    35101 ataaatatga tattattaat tggttaataa aaaagaaaat ttttcatgaa aggtaagata
    35161 acaatggatt tcaaaagctt agggattagt gaaaatacaa taaatattct aaaaaaatca
    35221 ggaataacaa cacctacacc tatacaaaaa gaaagtatta aactaataaa agaaggaaaa
    35281 gatgtaatag cagaagctca aactggaaca ggaaaaacac tagctttttt acttccgata
    35341 tttgaaaata tatcattaga tataaatgat atacaagtac ttatactttc tcctacaaga
    35401 gaactagcta ttcaaataac agaagaagct atgaaactta aagaatctaa agatgtaagt
    35461 attcttgcag catatggagg aaaagatatt ggttctcaaa taaagaaact aaaaggaaat
    35521 attcatatga ttatagctac accaggtagg cttttagacc atctaaatag aaaaacaata
    35581 gaccttagta agttaaagac ttttgtttta gatgaagcag accaaatgtt gcttatggga
    35641 tttaaaaatg aagtggaagc tattttaaaa gagacttcaa acaaaaagca aacactatgc
    35701 ttttctgcaa ctataaattc tcaagtaaaa aaattagctt atagatacac aaaaaatcct
    35761 gttgtagttt ctattcaaaa agaagaaatc actcttaata atataaaaca agaagtagta
    35821 gaaactacag atagaaaaaa attagatgcc ttatgtaagg tactagatga agataatcct
    35881 tttatggcaa taatattttg tagaactaag agaagggttg acaatcttga agaagctctt
    35941 gctataagag gatataattg tcaaaaactt catagtgata ttgctcaatc aaaacgagaa
    36001 agaataatga aatcatttag aaatttagat atacaatact taatagctac agatgtagct
    36061 tctcgtggtc ttgatatatc tggagtaagt catatatata attacgattt accagaaaca
    36121 ccagaagact acatccaccg tattggtaga actggtagag ctggtgaaga aggctataca
    36181 tgtgctttta ttgaccctaa aaatgaacga atgttaagtg aaatagagac ggctatagaa
    36241 tctaaaatta gtagaagaat tatagaatta taatttatag attgcttaaa ataccaatgc
    36301 cacacaaaca ctgtaatata tagaaagcta cagaaaacat gtatcaatct atactttgct
    36361 gttatactat tttatattaa agaaaaaaga ggctatccaa agtaggatta gtctctttta
    36421 ttgtcaaaat aatgaaaata tatttgactt catataaaaa agagtgcctt ataaactaaa
    36481 agtccatttt gagacaccct ctttttatct tttattctta gttttatatt gcttgtttat
    36541 agttgtttaa tattagattt tgcaaataat cttaataaac atgcagatat attatctata
    36601 gtattcttat ctatagtatt ctctttagca atattttttg ctactacatc taatttacat
    36661 tttcatttaa ttccgctggc catttagctt ctggattttc ctttgcaaac ttcttattct
    36721 tataatgtcc tagtgtaagg aatggaatta ctatagtgaa tagaccaaga taaccacaat
    36781 atccatatcc atatttaaca atattactta atcctgtaag tgatataagc attgacacta
    36841 ccattattgc acaagctgta aatacccttc ttttcattct tgaagaaagg aaagaaagtg
    36901 ctttatggtc ttcaaatcta tttacaagac caaatatagt agttactcct gtagacatta
    36961 aacaaaggaa taatgcaaca ttataaatta tgtatatagt atgatttcca gattgacctg
    37021 caacataaag agtagggagt gttgtttgcc cagcagcaat aatttctcta taccatccca
    37081 ttagcatagt tacagcaagt cctaatgcaa ttgcattcat aacaaatgaa attatcattg
    37141 ccttagtagc ttcttttgag ttcttaagaa gtggtcttga acatcctgca agtgtaggta
    37201 taacaaccga ttgaaaacct gcataaataa aagtattaag tattggcttg atatagccag
    37261 gtgtgaaact cgttctattt gataatattt cagttatttc tggtacttta gcttttatac
    37321 caacaataaa aatagtaaga gtacatacta gaatagctat tgtcattgct gtagctgctt
    37381 tagatacaag catagcacca aatatagtaa agacaagaag tacaactcca ataataaata
    37441 cagctacaaa ataatttact cctatacttt gaaatactgc tgctgcacct gctataacag
    37501 cacttacagc tattaaaacc attagatagt aatatatctc ccatattatt tcaagttttg
    37561 gatatggtct ccaaagctca caaaataaat ccttataatt cctacaattg ttattattat
    37621 acattatgat aacttctctc atggtagcag taagtataat cattgctaaa attgccataa
    37681 gtggtgctgt ccatccatac tgcacatagt actgagtttc ttgattccct gtagcaaatc
    37741 ctcctcctgc atgtgaacta aaaagaacgc ttgcaacacc aaaaatggct aacatagagc
    37801 ccgttacttt tgctttcttt acactttttt gcatgaaatc atcctcccta aaatgatatt
    37861 aaaagttttt attttaacac tttattgata aaacaataac atttttgctc attaaattca
    37921 actatatttt tccaatgact ttacattttc aacttatttc tacctttata ttaaatattt
    37981 tttatatatt tattttattt tttaaatagt attcaaattc actttgtttt ttaattttat
    38041 gaaatatctt ttttaatgtt aaatattata cattttttct ttattattat ataatttttt
    38101 ctttattatt ttataataat aatagtatag tataaaattc cttcttttat tacattcatt
    38161 ggaattatca aactttaaaa gaataaatca atatattttg tgaaaaaata tactgtaatg
    38221 taagtaactt tgatttattt atatttattc taacattatt aatacataat aaaattgttt
    38281 attaatgaaa atatattctc attaaaaata aattttttta caatatttca tataaaagta
    38341 tattgatttc tcttaaaata aacgtaacaa aaaagatatt ttctatagaa aatatctttt
    38401 taaccttcaa cttaaatctt atatactttc aaatactata tacttatggt cagccctact
    38461 ccaacttcat ttatattcaa tatttcattc atcttcgctt ttaccttaaa agaaacacag
    38521 tgacaagggt acaacattct tatttcttct ttatccaaat attgtattgt actatctaac
    38581 ctattattca attcaaaaag atgaaaacca cctagtatac caataactct atcatctcca
    38641 catacctttt tagcatactc tactatatta caaattccac tatgagaaca tcctgtaaca
    38701 ataaaaatac ctttatcagt tttacaaact atagcagaat catctaaaac ataatcatct
    38761 tcccacaaat ctcctatttt acatttacca attttagctc ttttttcaaa atcatttata
    38821 gaaggtattt cacctaaaaa cacacaattc ttgcttagat taaatggctt atccttagga
    38881 ttatacataa aaatattttt aatttcctca gcagaaaatg gagctcctat gcttttctct
    38941 ccatgttttc taggtataaa acagttagga tgtgaaataa gttcaactgt agataaatca
    39001 tacctatttt ctaaaaactg gatacctctt gtatggtcat tatgcccatg agaaaaaaca
    39061 acatgagtta aatttcctaa atctatattt aatttttcag cgtttgatat gaatacatct
    39121 gaataccctg agtcaaacaa aatcctattt ccatcaatct caatataata gcttactgct
    39181 ggttctccaa caaagtatct atcaatataa gtattattgt cgactaaaac ttgtatcttc
    39241 aatctttcca taataatcac tccttaaatt tttatttact ttaaagtaca gaatctttag
    39301 tttaatagta cgacatcaca gaatatttta caatttaata tctttaattt tcataaatag
    39361 aaggagtcta tctcaaaata aagagataag attctttttc attgctaaaa tgataaatat
    39421 atttggcttc atacaaaaaa gagtgactta tgaactaaaa agttcatttt aagacactct
    39481 cttttataaa atatatttat catttacttt tatagctgtc taaaatctaa tagtttcaaa
    39541 cttcaatcta tacatgctgt atgtttgtat aatttgatat ttcagagtta acagtatata
    39601 aatcatcaac acttaaatca tgtatatctt tatgaccaga aattctagca aaagtcttaa
    39661 gttcttctaa acttacattt aaaaagtttg ccactctatt agcactattt tctatatgta
    39721 atctttttct caattcctca tcctgagtag ctactcctac aggacactta ccagaaccac
    39781 atatacgata ttgttgacac gccgctgcca taagagcaga acttgcaata gcaactgcat
    39841 cagcccccat agcaattgcc ttagcaaaat cagtagatat acgaagccca cctgttataa
    39901 ccaaatctat atctaatcca tgtgtatcta tgtattttct agcacgataa agagcaaata
    39961 ttgttggaat tgaagttgca tctttaagca actttggact tgctccagta gctccaccac
    40021 gaccatcaat agttacaaaa tcaggtttag cataagctat aaattccata tctttttcaa
    40081 tatgacctgc tgaaatttta acacctattg gacgcccttc tgaaacttct ctaagttcat
    40141 ctacaagttt ctttaaatcc tctttggatt gtatttcctc aaaacaagat ggacttatta
    40201 catcttgacc tacaggctta tttcttactt ttgctatttc ttcagttact ttttcgccag
    40261 gaagatgacc tcccatacca ggttttgttc cttgaccaat ttttatctct atagcatcag
    40321 aatttttaag attttcttca gttacactat atttatttgg tacatactca aaaatatact
    40381 tgtatgaagc ttccttctct tctggtaata tacctccttc accactacac atagctgtct
    40441 tattttgggc tgcacccttt gctaaagcta tttttagttc tttagacaaa gctccaaatg
    40501 acatgtggga aatataaact ggattttcta taatcatagg tttctttgct ttttttccta
    40561 ttattgttgt tgtatttact tcatcatgct catttaaagg taatggattt aattgagcac
    40621 ccataattaa aatatcatcc caagaaatta ctggtagttt agttctcata ggttctatta
    40681 tagattttcc tgtaacagcc atttcgtgaa ttatatccat atgtttctca acttcatcat
    40741 ctcttcttaa atatgtactt aagtaattta aatctccctc tttttcagta tttaatttag
    40801 attcatcttc aactatgtct tctgctatct tttcatcttc ttcatagtaa acagtactta
    40861 tctttccaaa ataactacga ccttttgtac atacagggca ttcccaatct tcacttaatt
    40921 catcccatgt tttatcattc ttagattcat cataaatata tccacaaaca ctacatttat
    40981 aaattgacat attattttct ccttatatta tattgacatt aaacaaaatt aaaacttgaa
    41041 tttatataaa tttataggag gctatttgta tgaaaataca tttatagcct cctttttgac
    41101 tcaatttatt taaatattac agttcagcct tccataatcc atgtaaatta cagtaagcat
    41161 aggcagaaat cactttatca tcatcattca aagcaaattt aactacaggt tctccatcta
    41221 ctgctagaca tttgcgttga ccaccttgtt cagtcataag atacacccat gctatatgat
    41281 gttctttagt cattggatga gttgtgctac ttactttaac agtaacatta tttccatcca
    41341 cttcaattac aggtacatgt ttttcaactg ctgcatctgt tgtattagga acaagttcct
    41401 tcataggttt tccacaacag aaaataggta caccaccact ttgtatcatt cctacaaggt
    41461 ttccacaagt ctcacatata aaaaattttt gttcactaca cataaactca cctcattaat
    41521 tatttttaga atttgaaaac taacctactt ggctacacct tttacaatta ttacaaatcc
    41581 ctttaaaact tatgttataa gatgttattt ttatgtctgt ctcctcagat attaattctt
    41641 gtaaattatt aagaacttcg gattctaaat cgtatacctc tccacatact tcacatatga
    41701 tatgatagtg attatctatt cgaccatcaa atctatctgg ataccctgga atactaacct
    41761 ttcttataaa gccatgttcc gttagctgag ctaaatttct atacacagtt cctaagctta
    41821 aattcggatt atcttttttt aagttttcat ataggtaatc cgcagtagga tgaaccggat
    41881 tatttaatat ttcatttaaa atcagttctc gttgtttaga aaatttcata gttaacattc
    41941 ctttttaata atgataattt ttaataattt tcagctttta tattaaaata tgcttttgga
    42001 tggtcacata ctgggcattt ttctggtgct tcagtaccta catacacatg accacagttt
    42061 tgacattgcc aaacaacttc ttcatctctt ttaaatattt ttccttcatt taagttttct
    42121 aaaagcttta agtatctttc ttcatgctct ttctctattt ttccaacagc ttcaaataaa
    42181 taagctatct tgtcaaatcc ttcttctcta gcttctttag caaattttgc atacatatca
    42241 gtccattcat agttttcacc tgctgctgca tcctttaaat tttcctctgt tgaaggcata
    42301 ccatcatgta aaagtttaaa ccataattta gcatgttcct tttcattgtt agcagtttct
    42361 tcaaatatag cagctatttg attataacct tcttttcttg cttttgaagc gtagtatgta
    42421 tatttatttc ttgcttctga ctctcctgca aatcctgcca ttaaattctt ttctgtttta
    42481 gttcctttta agttcataat taattcctcc ctttttaata atagtaatga ttactatttc
    42541 tatatttata tagtatatca tttgccaatt tttgtcaact atatataata ttattttttt
    42601 tatttaaata ttcctatttt caaatatatt atttaaaaca tatattttag aatatactta
    42661 atgtaatata taaaacacat atgacagtac tctctcttgt tactatacct attgcaagta
    42721 ttatgatagt cgtgatttaa taaatacaaa aagaagctac agttatgaaa aatcaaaact
    42781 gtagcttctt gaatacatga gcatatagcc actgtacgac agattttttc ttttcactgt
    42841 ctagcaactt aaataataga aacaatattt atgttattta tgagaatact ttttatgctt
    42901 tatccctttt ttcttagata tggtcataac tttatcataa ttaggtgtaa atacaagtag
    42961 aatagttgtc aagattagaa ttacaatcaa agtcatagca ccgataagtg gctgataaac
    43021 agtaccagca ccattgttgt atccaactag accaagacct gctgtgattg gataaaagtc
    43081 tgtcagattt cttccagcaa caaacacacc acaaaaaccg tatacaaatg caatccctac
    43141 acccgtcaga aatgcatttt gtttacgacc aaaataagca ataatcggca aaacagcaac
    43201 ataacaatac agattaacag acaaaatctg aactaaggat tttacaacga gtataacaga
    43261 tatattgata ttgcaaaata acaaccccaa aataaatgtg cataagaagc tgaaaagact
    43321 taacaataca gtaattcctc caaccgcaat taattttccc actagcaatt tgcgtaatga
    43381 aataggaaca gttaggatgt tttttaaggt ttggtctgta tattcacggt taataagata
    43441 tcctccaata agtgtaatcc caaatggaaa actaagactg aaattattcc agataactcc
    43501 gtttgcaaag ctctcatacg ttagagggtc actgccgtgt gaacttacaa cctgaaaaac
    43561 tgccaatagt gctgaaaaca gaacagcaac aacaccaatc catagaatat tatatctttt
    43621 tattttttga aattctgtag taattatatc aagcatagat acctcctaat tctcctgctt
    43681 tttgtatatc atacaaatca gcaggactgc tataatggtt atcaaacata aaatacctac
    43741 acaagcagga gttgagagca aatatggctg tctaagtacc gtgtattcgc cagtgggatc
    43801 tccccaaaat gccatccacc aacgcattat aacaggagca ggtaatacgc ttaatagtgg
    43861 gttatttggt tcaaaattga taatatttaa ggatatacta aaattgaaaa tagcatatac
    43921 aaaagaaagt ataatagaaa aaatatagct gcgattgaaa tatacaatga gtaccacaac
    43981 aggaagtaca gtaacaaaaa acataattcc aaaagcaatg ctcattccta attttacagc
    44041 aaccccctct actattccaa caatgaaacc tccaatgata gtagctccta accctgcaac
    44101 agagtagaac aatgatataa acagcaacac agccaatttt gccagagcca gttttccttt
    44161 tggcactggc actgttgcaa gattttttaa tacatcatta tctctttcta taaaaaatag
    44221 ttggctagca acaatactta atacaattgg taatagcaag aaatatccaa aattgacaac
    44281 taatttgaac aattgctcaa agggcaagtt gtcctttgca atcaaaattg ttgcgggaat
    44341 tggaaataag caagcaccta aaatagaaat cagtataaat tttaaccgct tgagttttga
    44401 aaattcacat gaaattatat caagcaattc cttcaccccc tgttactttc ttgaagtaat
    44461 cttcaagagt atcttcgcat aaatgagatt ctgatacctc aatgttgttt agaatgaaag
    44521 cacgatttat ttctgcaaca gaaacatctg tatcatatag cataatattg taattatctg
    44581 ctactttgaa atttttcagg ttaagttggg tttccagaag ccttgctgcc tgtgctgcat
    44641 cagatacagc aaaatgtatg tatttactgt ttttttcttc taattgggca agactttctt
    44701 cctccaacaa aataccatgg tcaataatgc caatgtcatc tgccaacaag gcaatttcag
    44761 aaagaatgtg actggaaatc aaaatagttt tacctcgttc tgtgcagaga tcacgaataa
    44821 acgttcttac ttctgcaata ccaataggat caagtccatt gataggctcg tccaaaatca
    44881 acagttgtgg gtcatgcata atggcaagag caatcgccaa cctctgtttc ataccaagag
    44941 agtattgaga aaataacttt ttgtcattgt ttggcaaacc gactacatcc agtgctgatt
    45001 ctactgcatt tttttttggt attcctctaa gccttgcaaa gattttgaga ttttctgttc
    45061 ctgtcagatt aggataaaac cctggtgatt caatcaaaca tccaattcga ggaagaagct
    45121 tcttctcgtt attgtgaatg tcctgaccaa atattttaat ttctccagta gttggttttg
    45181 ttaggcccaa taacattttc atagttgtcg tcttacccgc accgtttctt cctagcaatc
    45241 cgtaaatgcg acctttctga acgtgaatat tcaaattaga aacgctcttt tgagcaccat
    45301 attgcttagt gagatttttt gtttcaataa ttaaattatt cataaataat aaaagcctcc
    45361 tttgtttatt aaagttatca taccacctca atcttacatt aaccttgcaa caaccttgta
    45421 ttaaccttgc aactttataa cttacaaaaa atccccctgt gtatacatgt cacatggggg
    45481 aaaaacaatt ttatattaat ggtaagctca ctgtaaatac ggtatacttt ccaatctcac
    45541 tttctacgga aacctgacca cccattcgct ccaccatttg actgacaata gatagaccaa
    45601 gaccacttcc tttttctgaa cgtcctttat cacacttata cagtcgctca aaaatatgtg
    45661 gtaaattttc tctggcaatc ccaacaccat catcctcaac acggagtaat accattctgg
    45721 aatcctcact catggtaatc ttgatttgcc gagccttact gtgagcaaga acattttgaa
    45781 ccagattatt gaccacacgg gaatatccat ctgggtcgag gtttaccatt agtcgatttt
    45841 ctggaatatc aatttcaaaa ttcagtttct tttcatggaa tataggaatc cagtctttca
    45901 aaatattgcg tgacaactct gcaatttcca cagattctat tgacagcgta aattcatcag
    45961 agttcaaccg aaaccagtca aaaagaacat caatgtaatc cttgaggtcg taggctctac
    46021 gcctagcgat ttcaaggtat tcctcccgct cttgttcgat aactatacca ctgtgtacag
    46081 catccagata accaatcaga gttgttaatg gtgtacgaac atcatgagat aaacttgtca
    46141 taagttgttt gctagcttta tccgactttt tcagagaaag taacttattt tcataatcgt
    46201 agacaatctc attaagctga taaaccaatg gagccataac atcacatggc ttaattagta
    46261 ttttacgatt ttcgtctcca atttgtacat cagcgagtat ctcctctata tcttttaagc
    46321 gtttgtgaat atgcccaagc ttggaaaaag caaatatgga aagaaaaagt agaccaatcg
    46381 acagcaagag taagaaaaga attatcgttt gttcatccat tttcatacct ccgtgttgaa
    46441 ttgataccca attcctttta ttgtttgcaa atagatggga gatgatgggt ctagttcaat
    46501 tttttttctt aggcgactga taatagccat gatattgctg tcatcatata catatggctc
    46561 accccacacg gcttcataaa tctgctgttt tgtcaaaatc ttaccctgat gccttgcaca
    46621 gtaaagaagt acaccaaatt ccttgggtgg aagcaacata ggttcgccat tggtagtaac
    46681 tgtatgctgg tcaaggtcaa tcaacaaacc tttgaaagaa agttgctgtg gctcctcatt
    46741 ttttggatta aaacgggtgt aacgtcggat taaagacagt acacgagcag taaattctgt
    46801 aatttcaaat ggtttggtta gatagtcatc tgcaccagct cgcaatccat gcactttgct
    46861 gtaattatca ctttttgatg tcagcattaa gataggaata ctgctatatt ttcgtatttg
    46921 ttccatagtt tcaaaaccat ccatacctgg catcatcaca tctagaacta ctaactgata
    46981 atcttgtttt gaaagttcaa ccagtccatc tctcccagaa tggcaatagt ttgcttcaat
    47041 ctgttcaatt gaaatactct tttttaacaa aatacaaaga tctttatcat catctataat
    47101 taaaacttta ttcatcttag ttcccctttc tacactcatt cgtagacttt tttatcacta
    47161 ggaatttagt catattgtag tatcttgaca tcacttagaa tatgttcctc aatgaaatag
    47221 tagtttatca tatgaggatt tatatctcat ttatcactta cttcttcaag tgtaatgcga
    47281 ttcttatacc tataacaccc attagtatat ttcatcattg tgaaaaaatc aagcgtatta
    47341 taagtgtgct tgaataaaac aaacatgata atacatttac tatatacaga atggtagatt
    47401 tgcatgttga gaaatgtaaa aagtagatat acatctgaag tacaggcgta taaacattaa
    47461 agttgtaatg atataaaggt ttaaaaaagg agttgagctt caaatttaat taaaaaaatc
    47521 aattttaaga caaccccctt aagtaatgca attattcata tttaaagtgc agttaatttt
    47581 taatttttta taatattact agcatattaa gatattctaa ctattttcgc ataattctcc
    47641 taaaatctta tgaatatgaa tcatcaaata taactcctct tgtcttggta attctctgga
    47701 gtattcctta tacatataag ctcctacctt tttcacacat tcatactctt ccttacaatt
    47761 tttttgaact tgctcatata taaaatctat tttttctctt gatggttcat tagccagaaa
    47821 tctttgtgaa aaggccttta gatgcattac aaatctccta taataaaatg actctttatt
    47881 atatacaata gaaaagtgat aatgaactat ttgcaaaata gcatttacaa ttttagcact
    47941 tctcttattt ctatcactat aaggattatc ttgttgtgca tttataaaat ggcctgctat
    48001 attaccaatc tcttcttctg gtaggtctaa accaagaacc tccttaaaaa cagtaatagc
    48061 atattttcct atatcatact cttttggatt aaattccttg atttcgaaca aatagtgatt
    48121 ttcaatcatt ataccttctt taaaacgtct cactgcaaag gcaatgtggt cagttaaggc
    48181 caaatatata tggttcataa gttttaagtt atatttttct attccatatg caattatcat
    48241 ttgagctata ccaaaatatt ctgcatctat ttctgttgcc aattgtataa tactcttttt
    48301 tatattttca tcatgaagaa caaaaatctt ttctatatct ttttcattta actcagaccc
    48361 ggccttataa ttatggccaa tgcctttccc catcaatatt atttcttcat cattatcatc
    48421 ctttgcaagt agcaacgaat tatttaatac ctttgtaatg tacatactaa aaccctcaat
    48481 atatatttat gtttatttta ctattccatt gttctctata acttctttat accagtaaaa
    48541 actatctttc ttgattcttt ttaaatctaa aatttcatgg tcagttctat ttatataaac
    48601 aagtccataa cgcttattaa aaccttgaga agaacttaaa aggtctgtaa atgaccatgg
    48661 acaatatcca atcatctcta caccatcttc aatagctagt ttacatgcat ttatatgact
    48721 tcttaaatag tctatacgat agtcatcatg aattttt
//
LOCUS       DAJMZY010000021        45960 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.021, whole genome shotgun sequence.
ACCESSION   DAJMZY010000021 DAJMZY010000000
VERSION     DAJMZY010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 45960)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45960)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45960
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.021"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            397..1614
                     /locus_tag="OE968_001146"
     CDS             397..1614
                     /locus_tag="OE968_001146"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase"
                     /protein_id="HCP7218436.1"
                     /translation="MMNVTLTDVKEARETIKNIVKRTDLLESVKLSEKTGANVFYKCE
                     NLQKTGSFKLRGACNKIASLTDEEKANGVIASSAGNHAQGVALGAKMTGIKSTIVMPA
                     TAPLAKVSATKGYGAEVVLNGAVYDDAYAKAVEIQKETGATFLHPFNDKYVIAGQGTI
                     SLEIFEQLDNKVDTILCPVGGGGIISGVAVAAKALNPNVKIVGVQTANIPSMKESIKN
                     GKVTTAFNDTTIADGIAVKTPGDLTFEIINELVDEIVVVEETEIAESILFMMESQKIV
                     SEGAGAVCTAAILSGKYVPAKDENVVCIISGGNIDINTLYRIIGVALAKEGRRYSFST
                     IMEDKPGNFAELTRIISENGGNILSANQGKLSAGEALGKQSAEFILETIDYDHIARIK
                     KAIEEKGFKIIEL"
     gene            1709..2089
                     /locus_tag="OE968_001147"
     CDS             1709..2089
                     /locus_tag="OE968_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HCP7218437.1"
                     /translation="MKHEVIHTNDAPAALGPYSQAIKAGNLLFVSGQVPLVPETMEVV
                     EGDVQAQTAQSLKNLKAILAESGADFSNVVKTTVFIKDMNEFGAINEVYAEYFGENKP
                     ARACVEVARLPKDVKVEIEVIAVL"
     gene            2373..2855
                     /locus_tag="OE968_001148"
     CDS             2373..2855
                     /locus_tag="OE968_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HCP7218438.1"
                     /translation="MLNFFKKNKSYKLHAVVSGNSINIEKVNDSVFSKKLMGDGVAII
                     PNSNVVVAPCNGKVTVLTESKHAFGMVSDEGVEILVHIGIDTVSLQGEGFKNEVSQGD
                     TVKKGSPIISFEREKINSQGIDCTTIIIVLNHSEFSEINCMVENEVVAGQDTVIEIMK
                     "
     gene            2876..3691
                     /locus_tag="OE968_001149"
     CDS             2876..3691
                     /locus_tag="OE968_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HCP7218439.1"
                     /translation="MRVVKIFNNNALSTVTNDRKEAILLGLGIGFNKRPGDKVNEDKI
                     EKIYYVQDHMQTKFLELLKNVSPEVMDASQQIISLIPGNEGKFNNKGILSLVEHISFA
                     IDRMKNNVFLPNLMLLDIKMMYSKEFELGVKALEIIYRVCHIHLPEDEAGYIALHFVN
                     LQSNDNLAYDTLKFVKGSIDLIKECYGLELDESSLSTLRFRTHLKFLAQRIFKNEICQ
                     DDKMIEMYDYLINNHPKNKEYLEKLNVYIEKEFRYKLDKPEKIYLLLHLTKIL"
     gene            3744..5294
                     /locus_tag="OE968_001150"
     CDS             3744..5294
                     /locus_tag="OE968_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HCP7218440.1"
                     /translation="MKEKLLGGLETFAKAMVQPLMYLSSAGILMVVGVLLTNDMLLGV
                     LPFFKWEPIQIFGSLIYNCIMAIINNLAVIFAIGIPAALAKKEKHKAALIGFMSYIIY
                     LTASNTMLTSLGQLAKESKMLGLIGTGQATILGIQVVDTSVFGGIILGYIAGYVFNRT
                     SNKTFKGALQIYSGANFSFICMFFVSILIGVVSNFIWPLAQQGIASLANVIKDTGTFG
                     LFLYGFLERILVPTGLHHLIYTPFQFSDLGGVLKVGADTVSGAYAIVMTEMNLPVERF
                     SDSIYYMATGFTKMFGYIGIGAAFIYTAYKQNKKKVKATIIPLIITAVLASVTEPLDF
                     MFVFCAPLLFFVHAVIAGLFIALLKIFDVTALCGGNLLVSVIMNTTVGVEKTHWPVMM
                     ILGLAQIIVYFVVFSFLIKKFNYKTPGREDESTATGEEQSKQLNLDAGIENIIDGLGG
                     KENINTVENCITRLRVNVKDESKINEDIINLTPNSGIVRKGKDIQIIFGLHVHEVRRA
                     VEDFLEAY"
     gene            5391..6743
                     /locus_tag="OE968_001151"
     CDS             5391..6743
                     /locus_tag="OE968_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-alpha-glucosidase"
                     /protein_id="HCP7218441.1"
                     /translation="MIITIVGGGSTFTPGIVKSIALREKELELEEIRLFDIDKKRQDK
                     VAVVVNWILKEDVKTDVKLTVTNCEKEAYTDATFIFAQMRVGKYEMREQDEKIPLKYG
                     CVGQETCGCGGMAYGLRTIQPMIKVIDDVEKYAKKDYWILNYSNPAAIVSEACRKLRP
                     NARIINICDMPIAIIDMIAGSLNINDVHNIRYDYFGLNHFGWFTSIDYKHRDLMEEIK
                     EYIKENKILLPKSYIENLNKSRSTGNRHAVSSWIHVWESVYTMLESFPKYLPNTYLTY
                     YLLSKETVEHSNINRTRANEVMESREKDLFEGVRHYLETGEISEKAFYAGSHGDWISD
                     LAVSIKNDTRSRFLVITENRGAIPNMPYDAMVEIPAYIGKDGPEVIARGPIPLFQQGL
                     MMQQLNSEKLIVEAYIENSYEKALQAFTLNKTIPSMNVAKEILDEMIEVNKEYWPELR
                     "
     gene            6874..7632
                     /locus_tag="OE968_001152"
     CDS             6874..7632
                     /locus_tag="OE968_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCP7218442.1"
                     /translation="MNIINKIFWQEDRIGMITNNLEADTHSHCMLQLFLGIEDSIEIT
                     VNEKLVKCNCIIVDKNISHSFSARKKVYYSAIIEPTSIYAEQLTSKMNDFGYWICDND
                     GLEKLRQQGTFLISNSSKEQYLRFMEMLNNYLNIPITLKHYDDRITELFNLLHTCNCD
                     NHTISSFADKVSLSASRLSHLFKEQIGIPLKSYILFHQMECAFRELLSGKNVTEASMT
                     AGFDTPSHFAGTVKRMMGMPVSLSLKDSEFLKVY"
     gene            7679..8398
                     /locus_tag="OE968_001153"
     CDS             7679..8398
                     /locus_tag="OE968_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
                     /protein_id="HCP7218443.1"
                     /translation="MNKEYLEETKMLNYNEPQLKLLVSSKNWLELDDFHKIKSIYEFV
                     QNDILFGYNASDMLSATQVLNDGMGQCNTKATLLMALLRAVNIPCRLHAFDVTKDFQR
                     GATSKLISLLAPKYILHTWVEVFYQDRWIALEGVITDKKYLEAIQKKFFNHGGTFKKY
                     AIATNDLKNTSIDWDGKDTFIQKEAIVYDYGIFPSPDVFFSTHSQHMSKLKNFIYVHL
                     IRKIMTKNVCKARNNYIDKNE"
     gene            complement(8522..9922)
                     /locus_tag="OE968_001154"
     CDS             complement(8522..9922)
                     /locus_tag="OE968_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HCP7218444.1"
                     /translation="METQSNNKKGNLIIAIVMTGAFISSLSQTLLSTALPNIMSDFKI
                     TADVGQWLTTIYLLIAGIIVPTTAYLINRFSTRKLFITSMSIFSIGCIIALFSNNFST
                     MLIARVLQAMGSGSLMPLLQVIILYLCPEEKRGAAMSLVGITVGFAPAIGPTLSGWLV
                     DSFGWHSLFLFLSPIAILDVILSFILLRNVGETQKLKLDIPSIVLSSLGFGGLLIGFT
                     NQGNYGWTNIATYLPILIGIMSLILFTLRQLKSKEPFLELRVFKNKPFLISTILIMIV
                     YASMMSATLMIPLYVQSVRGFSALSSGSLMLPGAILMVVLNPIAGRHLDKYGPHALSI
                     LGTGCLFLGTLSFAFLGRDTSLIHVSLMYCIRMIGISMVLMPLTTWGIKTLDRELISH
                     ATAINNTLRQISGAIGSAILITIMTSATKKAHMSSNMLSNIHGIDVAFSIAATLAFTG
                     LIVSICFIKRHQIIRS"
     gene            complement(9926..10834)
                     /locus_tag="OE968_001155"
     CDS             complement(9926..10834)
                     /locus_tag="OE968_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCP7218445.1"
                     /translation="MKGDNKVTEKQRLIITIAQKIFDQKGFQNTSISDVVKECKMSKA
                     TFYKHFETKESFICEIINYYDEKFLEIIHSINENNDIPASEKLNRKIIAVWKNIFSRT
                     TINTYIRENFSEEQRKATSKLQTKSRANLLNEYKLSLFDNYGDKIEKIIFDLVFLLDA
                     LIHQFIYIIHVQKREINVYFIAKFTIQILDLVVENMDNLNPLIEKSMFLHKQEDEVYF
                     SLHNKSLFFKMIQDIEELIKTDTSLLENPKLLEAIKKLYVEGKNQQYDSLIMDAMIAY
                     LEKEDTLRPKVLLLNSIKNQLKKETL"
     gene            11095..11742
                     /locus_tag="OE968_001156"
     CDS             11095..11742
                     /locus_tag="OE968_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HCP7218446.1"
                     /translation="MKKKICVAIIFALFIVFVEMFIDSSSEGSKIMTAELSKYRKGVN
                     VLSINNIIVANKKYSLPKDYSPQESSEARDAFYKMNKDAQKSGLNLKAFSTYRSYEYQ
                     DRLFKSYVKEHGEKEANRFSAKPGESEHQTGLAFDIGGDDQSCWANKKFNNTKEAKWL
                     YENAYKYGFILRYPEGKENITGYMYESWHYRYVGTEHSKNFAMNNLTLEEYLHIN"
     gene            12066..14705
                     /locus_tag="OE968_001157"
     CDS             12066..14705
                     /locus_tag="OE968_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HCP7218447.1"
                     /translation="MSYKSTYQEVIKNLDSSLSGLSKERAEELLEKNGANELKEADKV
                     PTYKLFLESFKDPLVIILLIAALVQIFLGETVESIIIFAVIIINSVLGVVQTKKAESS
                     LESLKNLSAPNAKVIRDNKKMTIPAKNLVVGDIVFLEAGDYIPADGRLIEAQSLKVVE
                     GMLTGESEPVLKHTEKISEDVSLGDQKNMVFSGAVVVYGRGSFVVTGTGMDTEMGKIA
                     GLLESAENKLTPLQQKIEDFSKKLGVGIVILALLIFIIQVARNYFMAGNGEMTQIILD
                     SFMFSVAVAVAAIPEALSSIVTIVLAVGTNSMAKKQAIIRKLPAVETLGSTSVICTDK
                     TGTLTQNKMTVVDYYMYGTNNDELDKEKVNYSYHAKLLTMVSTLCNDSHITSDGKEVG
                     DPTEVALINYSSKNDLDYDKLRSKYIRINEIPFDSDRKLMSTVNSIYGDYIMFTKGAP
                     DIVFSRCKYALKNGSKVDITDEIIEEYKHKNEEFSNRALRVLAFAIKDVPEEDFIPSI
                     DDEHDMTLVGIMAMIDPPREEVMDAVKEAKSAGIKTVMITGDHKTTAAAIAKEIGIME
                     EGDLALTGKELDALSEEQLYEKLENISVYARVSPENKIRIVKAWQHKNNITAMTGDGV
                     NDAPALKQADIGIGMGSGTDVAKDASAMVLVDDNFASIVNAVEVGRTVYSNIIKSITY
                     LFAGNLGAIVSIVFAVFAGWSNPFTALQLLFINLVNDSLPAIALGFEKSEKNIMNKPP
                     RHPDESILAGGTLKAVAIRGCIIGVVTIIAQYIGLQVSPELGVAMAFSTLILARIMQT
                     LPARSNNQTVIKLGFFSNKYVIGAVLVCLGLYSLTLIPVLRGIFSIPTTFGLYQLGIC
                     LGLALISSILMELNKLINRSEVK"
     gene            complement(14763..15866)
                     /locus_tag="OE968_001158"
     CDS             complement(14763..15866)
                     /locus_tag="OE968_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate aminotransferase family
                     protein"
                     /protein_id="HCP7218448.1"
                     /translation="MKLKINKAIEMQLKKSYAIESGHSEDVFEIDCGEGINTVSYSNK
                     AVEAFNALKFDMIRGYPHSIALKDNIVDYWKDFIALDTDRICLADGSIHVIYLLNRLF
                     IEKGDKVLGYSPQFSEYETDIKMHGATYDYVLLKKEDNFKFNEKEFIEKINPEYKVIY
                     IDNPNNPTGQIIHLSSIENIVKEAAKYDIAVMVDEAYGEYMPKENSAVKLLNNYDNVI
                     ALKTFSKGFGLAGLRAGYAVLPEQLVSPIKKISTPYEVSEISRSIAANLLDDVQFIEE
                     LKEKTKDIKNQLLIPWKNLNIAETSDTVSIMTVEHKNKDIDLQQEFAKLKIRVISGSD
                     FTGLDKNFIRFRMPEEKELPEVIKAFQIIDNIE"
     gene            16227..17048
                     /locus_tag="OE968_001159"
     CDS             16227..17048
                     /locus_tag="OE968_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HCP7218449.1"
                     /translation="MGYKLIVTDMDGTLLGNNHKVTDENKTALQKVIKSGINVTLATG
                     RAFDSAKCNVDFLKEDMPIIACNGSLIREQNGNIIYSNKIDTRTCLNILDVLDKYDIY
                     YQCNSIDSMLSKKIEGREDRLSVFLGSETEVIVKDDLREEIFKKDILKFVIIEEKNPS
                     ILDEIRKELRKVQGIKITSSWPNNIEVMNEGVDKGNAVKILAEKMNIDREDIIAFGDN
                     YNDIEMIKFAGLGVAMGNAEELIKQEADYVTDTNQDSGVAKAIYKFLELKESLSS"
     misc_binding    17127..17338
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            17425..18741
                     /gene="argH"
                     /locus_tag="OE968_001160"
     CDS             17425..18741
                     /gene="argH"
                     /locus_tag="OE968_001160"
                     /EC_number="4.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012101354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HCP7218450.1"
                     /translation="MKLWGGRFRKAENQLMEEFNKSFGYDCVLYKKDIEGSVAHVHMQ
                     VKCGLLTEEEGKSITEGLKGILEDVENGKLVLDGEYEDIHSFTEINLIQRIGDVGKKL
                     HTARSRNDQVAVDMRLYAKEKANDLVGLISEFKATIKDVADKNPVMMPGYTHLQRAQV
                     VTFKHHLMAYYSMFDRDEKRIKNAIEILDESPLGCGALAGTTHDIDRSITCEQLGFKK
                     VVDNFMDGVSDRDYLLELMSDFSIIMMHLSRLSEELILWSSQEFGFVEIDDLYTTGSS
                     IMPQKKNPDGAELIRGKTGRVYGNLFGLFTVMKGIPLAYNKDMQEDKEGFFDSVHTLE
                     MCIQIMDRMIATLKVNEDKMKQAVKNGFLNATEVADYLVKNNVAFRDAHGIVGSIVIY
                     CEDNKKAIEDLTLEELHKFSDAFKEDIYDFIDYESILNKGIKKNLK"
     gene            18990..19328
                     /locus_tag="OE968_001161"
     CDS             18990..19328
                     /locus_tag="OE968_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2325 domain-containing protein"
                     /protein_id="HCP7218451.1"
                     /translation="MNLLVIGGHERMEKDYMVMAKKKGYKTKVYTTMSSKLNNSIGRP
                     DAVVILTSTVSHKMSRTVESQAKKQDILIVRHKNSSKVAFNECLDMVDECLGNCSKCK
                     LKDKQKQKNI"
     gene            complement(19455..20744)
                     /locus_tag="OE968_001162"
     CDS             complement(19455..20744)
                     /locus_tag="OE968_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HCP7218452.1"
                     /translation="MKRNLSLLLICLLIFTSFLGSSNISFADNEPAIVAKHAVLMDYE
                     SGKILYNKDGNSKLYPASTTKVWTACLVLKEVKDLNQVIEIKDLPQIDGSSMYLKNGE
                     SFTVKQLLDALLVHSANDAAFVLARYVGGGNVQKFIDLMNSEAKKIGATNTHFNNPHG
                     LPDPNHYTTAHDMALIAREAMNNDTFRQIVKTKSLKFEATKAYPYERYFVNTNKFLTS
                     HDKITYKGQPINIKYDIVDGIKTGYTDAAGKCLLSSAVKDGRRVIVAVFNSTNADLYL
                     DSRILIDYGFDNFKCATIVDKEKYTDTKKVLFTKQHELIYEPKNSYRIFLEKDESQGN
                     YDTKTELNKIDLPIKKGAKVGTLNVYNNGKLENSIDLIAKNNLDSSLPFFTGNNILMT
                     FVKIIAGILVLLVLFIIASNIKKKKRKKARSKKNMKK"
     gene            20824..21528
                     /locus_tag="OE968_001163"
     CDS             20824..21528
                     /locus_tag="OE968_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HCP7218453.1"
                     /translation="MKKKVKFISFFVLFILIISSIIVYKSLIFKDDIYVVSKKNLPNE
                     KTHVVENEIKGEDNNHNKVTKDIDKNFQNNKITIYISGAVNRPGIVTIESDKRLYDAV
                     ELLGGTTKEADLNGVNLSVRLEDEQHYIIPKIGEATSVTSNDDSNKPNQRNESRGEPK
                     NKSNKNISNESKVNINVATIEELDSLPGVGEATANKILQHREENGQFSSIEEIKNVNG
                     IGDKKYENIKDLICVD"
     gene            21620..22666
                     /gene="selD"
                     /locus_tag="OE968_001164"
     CDS             21620..22666
                     /gene="selD"
                     /locus_tag="OE968_001164"
                     /EC_number="2.7.9.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015617929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:21668..21670,aa:Sec)
                     /transl_table=11
                     /product="selenide, water dikinase SelD"
                     /protein_id="HCP7218454.1"
                     /translation="MKKEQKKLTEMTTAGGUAAKIGPEVLASVLSQLPKNDNIENLLV
                     GLDTADDAAVYKLNDDMALIQTLDFFTPMVDDPYVFGQIAASNSLSDVYAMGGKPLVA
                     MNIVCFPSCHDMDVLAEILKGGFDKVKESGALLVGGHTVDDKEPKYGLSVSGIVSPNK
                     VLSNATAKPGDKLIITKPIGVGVLNTAMKEGMVEQHIADKVIEIMIHLNKYAAMSFEK
                     FDVNSVTDITGFGLLGHTLEMAKASEVSIEIESKHVPIIEGAIEMAQMGIIPAGMYKN
                     MHYVSKDVEVVGNIEVAVQDILYDPQTSGGLLISVKEELAEELVKDMKLNGAIEAKII
                     GSVVPKGEKYITVL"
     gene            22684..24096
                     /locus_tag="OE968_001165"
     CDS             22684..24096
                     /locus_tag="OE968_001165"
                     /EC_number="2.9.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-seryl-tRNA(Sec) selenium transferase"
                     /protein_id="HCP7218455.1"
                     /translation="MIVLSKRELFAMLPSVDEVLSDNRIVEIINEYPRSLVLESVREV
                     IDLKRQFILRLKEDASNSVTIEFGEIIESAIERVKLNYSLSLKKVINATGTVIHTNLG
                     RSLLSEDIKDELWCAASRYSNLEYDLDNGERGSRYSHLTSTIKRLTGAEDVLVVNNNA
                     AAVLLVLSTMAKGGEAIVSRGELVEVGGSFRIPSIMALSGAELVEVGSTNKTHLKDYK
                     EAITEDTNVLMKVHTSNYRIMGFTESVSIEELVNLGKKYKLPVIEDLGSGVFIDLSKY
                     GLSYEPTVLDSIRQGADVVTFSGDKMLGGPQAGIIVGKKEYIEKMKKNQLTRALRVDK
                     LTICALEATLRMYLDETKAIENIPTLKMLTYKIEELEVKANKLFEKITALNLNANINI
                     EDGFSQVGGGSMPLETISTKVISITPEHMNVSSLEKKLRLSEAHIIARVYDNKYVLDV
                     RTIFDDEFDVIVEELRKAFN"
     gene            24210..26093
                     /gene="selB"
                     /locus_tag="OE968_001166"
     CDS             24210..26093
                     /gene="selB"
                     /locus_tag="OE968_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="selenocysteine-specific translation elongation
                     factor"
                     /protein_id="HCP7218456.1"
                     /translation="MKNVVIGTAGHIDHGKTTLIKALTGRETDTLDEEKKRGISINLG
                     FTYFDLPNNRRAGIVDVPGHEKFIKNMLAGASGIDIVLLVVAADEGVMPQTVEHLDIL
                     SFLNIKNGIVVLTKSDTVDDEFRELVKEDICEKIKGTFLEDAEIIEVDSISKRGIDTL
                     IEKIDKMSDDIEDKNENSPARLNIDRVFSIKGFGTVITGTLIEGKISIEDDLVIYPQV
                     LKTKIRSIQVHGENKDTAYAGQRTAINISNVKVDDIKRGDVLAAPNSLEESMMLDVKL
                     SLVNHLDKGLKHWDRLRLYHGTREILCRAVPLDKELIESGESGYVQLRLEESIVSKKG
                     DTFVVRRYSPMETIGGGVIIDPSPKKHKKFDEKVIEALKIKEKGELKDIIEEYLKRNL
                     KNYPNIKEIMSYSGAHEEDVKRALETLISEDKVFIIGNMYMHINQYNKLKENTIKLLS
                     EYHKKYRLRKGILKEEVRSKIESNFKTREMDILLEKLSTENAIKIENNIVSLLDFEVI
                     LNDKQKEIAKKIEKRLKSCGVSSILTIDEVSEGNHNYAEVLESMIGNKVEKLDDLYIM
                     DKDIYENAKNILINYIKENKEITLGEYRDLIDSSRKNCMIILENFDRNKITKRVENKR
                     ILF"
     gene            26198..28936
                     /locus_tag="OE968_001167"
     CDS             26198..28936
                     /locus_tag="OE968_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation-associated two-component system
                     sensor histidine kinase"
                     /protein_id="HCP7218457.1"
                     /translation="MKNIIPDVKPDIKEREDMSLLFIIMGSVLLLFIIKDIEKYETLL
                     HAIYTIFLVATGVIIFNTTKFKVDSFSTFLGLIFIATGVLECIYLFNSLGIKTKSIME
                     INITISAITDLFPILGVYLSFKFVKDNKQIYSSVILFIATATLTITSLFIISGICDYL
                     GNGKSQYALGVIISIFIIIISIISGIELNSSSNKGKWEYDEKKIFNRIIVIIILSRVP
                     NLLHIVIDNRNVERILSQIIINVALYYLYNYIVSKNIKKTALELHDTNEELTKKTESL
                     KEKNKKLIYETEKIEELKGILMKRESRLQSTLDVAVNSIVVFSKDGEITYANKSFRNT
                     FGDYKEQDKLTDKIKNFNDLIESIHYVFVHEKNAEKLISTSDNKVYQAIFAPLIIASQ
                     TEGVLCVLEDKTKKKEYERKLIEANKRSKDFLESIGDGIVVLEGNNKIYVNNACREIF
                     KNNLESIDFSLVCKSEESIEKRYVIDGEVKYVEMSFSQYTNAGTNKTIIVIRDTTSRK
                     ISQIKLEESQSSYSRFIDILPDGICLLKEDLSINYANKSFLDMLAFTNIDDIKDSNIK
                     LLMNANTEEKMKFTDNMAKVLNENRSILLLEYELINSYDDIVEVELSALPFAIYNTRY
                     IMLIIKDLVHKKYSEQAEKELLERFKTDKIKTEFFANMSHELKTPLNVISSSNQLVDS
                     FYRNEKIKDYNNNIKSHVDLVRQSSYRLQRLINNIIDLTKMESGFYTLKLAKYNIVSV
                     IEDLFMNIEEYALRKDIKILFDTDLEEINVYIDKVEIERIMLNLLSNCIKFTDNGGWI
                     YVSIHYKIDKVIISVKDTGVGIPQDKLELIFEEFSQVDKTLSRNTEGSGIGLAIVKNL
                     VSLHGGDIEVVSEVNKGTEFLISLPMKGFSSEHYTEDKRIYNIQEKIKIEFSDIYY"
     gene            complement(29055..29999)
                     /gene="manA"
                     /locus_tag="OE968_001168"
     CDS             complement(29055..29999)
                     /gene="manA"
                     /locus_tag="OE968_001168"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HCP7218458.1"
                     /translation="MEPLFLKPIFMDRIWGGTALKDKFNYEIDSPTTGECWAISSHKN
                     GDCLIENGKYKGKKLSELWNKNRELFGNTPGDKFPLLTKILDANDNLSVQVHPNDEYA
                     KKNENGELGKTECWYVIDCSDDAEIIIGHNAKSHKEFVNMVNNNEWDKLLRKVNIKKG
                     DFFYVPSGTIHAICKGTLILETQQNSDTTYRVYDYDRTDNSGNKRELHVQKSIDVTNV
                     PHINFDTDYKIVSTSDFKCTTFVSNEFFSVYKLDVFGKCNFTHNTPFSLYSVLDGNGK
                     LIHNSVEYNLKKGMHFILPNDFGDFSFEGNLEIICSHI"
     gene            30172..31533
                     /locus_tag="OE968_001169"
     CDS             30172..31533
                     /locus_tag="OE968_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HCP7218459.1"
                     /translation="MELFKAESKKYKKEFLKLLEQWVSIPSFYDRKTVSKDMPFGKGV
                     YDALNWFENLGRENNFKVKNIDNHAVQIEYGNGKEYVDIFGHCDVVNPGEGWDSEPFK
                     LNIIGDKLVARGVSDNKGPMIVNFLALKMIKDLDINLKRKVRLIAGGNEESGFKCIKH
                     YYSKEPYGVCGFTPDAKFPVLNGEKGGAIIKLISNIDDKSLYISGGIEFNTIPDKVYI
                     KNVEKLGKDNICFDINNISINYDNGNYIVYGKGGHSSKPEKSINPILATIKLLSENID
                     EKWTKDLYKLINQDNINGNLFGLNIEGKCGILSMVPTIINIVDGKLEVVLSVRYPEIL
                     TIEDIIKKFNLYMEQNNINKFELIGENLKQANYIDRNSKLVRSLHDIYIKYSGDLKND
                     VRVTSAGSYASEMNNSVIFGCEFPDGSFGNVHSANEFASLDRFITAIGIYAEAIITLC
                     NKI"
     gene            31621..33510
                     /locus_tag="OE968_001170"
     CDS             31621..33510
                     /locus_tag="OE968_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HCP7218460.1"
                     /translation="MITKKHAIIVKSLSNKDGYMTSNELAIKLDVSTKTIKRYIADLN
                     SVLSKYDLVIASSRGIGYKLSGSKNNIARAVKEANKYIDGFLDDSEESRMSNIICMLI
                     NRNYMSIEAMAEELNLSIAAINKLSSKLKRKLEKYDLVIKSKPYYGSYIHGEEINIRQ
                     LITDYAIKLDEKSKVKVFLDDISENDIHCIESILEKHLREKDTIISDKDFNLLLSKII
                     VSVFRSKRGHSNNINLMDTSYRFHNYYFIENLMKEISDKIGFKLIEDEVIYISNYSGV
                     IAYKGTQGRKNTSEIEERISTVISSALQDIFLISGSDYTKDDEFMVAISDHIKRFLNR
                     ARANVKSNNPLLHQIKEKFPIAFNLAVFLSNKLETEFNLKLDEDELGYIAIHFAASNE
                     RMKKNTSKKICIVCHYGIGTGQLISEKLKQNISDLSVVGVYPVRYLDMAISQDVDLIV
                     STVELKGYEKPVLYIENIFDDSLIENVNKAFYEKEERRKIISNMFDEKAFFSIKASTK
                     EEVIISLSNKLKERDFIEESSIKSIIDRENISSTEIGNLVAIPHTIVKGDKKSIIGVG
                     ILENPIIWDKQEVQLVFMVFFNTKEKHNFSIFKYLYNFIKDEGGVRGIIKICDFNKLM
                     ALIGN"
     gene            33525..33980
                     /locus_tag="OE968_001171"
     CDS             33525..33980
                     /locus_tag="OE968_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HCP7218461.1"
                     /translation="MGTNIFNKEYVFLNVDAKSKVEVLKFISKKAKDLNLAEDESLVY
                     EGLMAREEQFTTNLGESIAIPHTKNDAIENPAVVVLKFNEDVVWNEGEDKVKLAISLL
                     MPGKSKENIHLKLLSSLSRKLINKEFKDSLLKSDNVEEISNLINEALGL"
     gene            34039..34356
                     /locus_tag="OE968_001172"
     CDS             34039..34356
                     /locus_tag="OE968_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HCP7218462.1"
                     /translation="MNKKLVALCACPMGLAHTFMAAEAIEQAAKALGYEAKVETQGAD
                     GVQNELTRDDILGATMIIHAVAITPEGMERFDGCEVYEVELQEAIKNAEGVIKEIEED
                     LGI"
     gene            34381..35643
                     /locus_tag="OE968_001173"
     CDS             34381..35643
                     /locus_tag="OE968_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HCP7218463.1"
                     /translation="MAIKKKVINSSGASTTGGNNVGKSTPSSPTQSKGNGKWKEISKH
                     IMTGISYMIPVLVMGGLIGALSQLIPYAILGLDPSVGIVDAMNSGEFTGFKLSLLNIA
                     QLMSNFGFTLFGFAIPLFAAFCANSIGGKTALIAGFIGGYIANKPVGVPQFVDGQWTE
                     VVPVASGFLGAILIAFIIGYFVKWLNKSIKVSHNWLAFKTTFLIPLIASLACMVLMIF
                     IITPFGGLINESMKNFLTAAGAAGEYVYATALAAATAFDLGGPINKAAGFVALGLTTE
                     NVLPITARTIAIVVPPIGLGLTTLLDKRLVGRRVYDRQFYQAGKTSIFLSFMGISEGA
                     IPFALERPGFVIPLNIVGSVIGAITGIILGAIQWFPESAIWAWPLVDNLFGYIIGIAV
                     GAIFIAVGNIFYRNKLIKDGKLVVDYID"
     gene            35748..36812
                     /locus_tag="OE968_001174"
     CDS             35748..36812
                     /locus_tag="OE968_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HCP7218464.1"
                     /translation="MDKIEKVREYFREYDIDGFLINSPTNKFYVGNLFSSSGYVFITK
                     ESQYIIVDFRYFEEIKRKSSLFNVVLMDKTRTHFDIINDICREQNIKEIGFEGNEVSF
                     DLYRSMSNKLSATLKSVDLSTLRETKNEDEIKYIKKACEIVDATFYHIVDFIKVGMTE
                     KQVENEIVRIIKDLGGQKESFDTIVASGLRGALPHGKASEKVIEYGDFVTFDFGAKYN
                     NYCSDITRTICMGTINKELEEIYNIVRKANEECIRVLRPGMTTGEIDKVARDIIGSYG
                     YANNFGHNLGHGVGIMVHEYPALAPESNEVLKEGMIVTIEPGIYVPSLGGVRIEDDVL
                     ITQDGCMRLTTSTKDLIVVS"
     gene            36866..38044
                     /locus_tag="OE968_001175"
     CDS             36866..38044
                     /locus_tag="OE968_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PatB family C-S lyase"
                     /protein_id="HCP7218465.1"
                     /translation="MYNFDDKPDRVSEKCRKWDLNIIRDKFGDIREDFIPMWIADMDF
                     KIPTEIENKFIEAVRRGVFGYTYCYDEFYDSVIGWQKNMHEVNVEKEWITLTYGTVST
                     LHYVVQAFCKKGDSIILNTPVYDPFESSAKKQGVNVICNTLDVVNDRYYINFDKLEVQ
                     IKENKPKLMMFCTPHNPSGRIWTIEEMTRVATICKENNVILVADEVHAEHIHYGTFNS
                     ILKIGKELLENVILLTSPNKGFNLGGLKTSYSIVINKDIRDKFRNKLKQNSITSPNVF
                     GIIGLITAYNECHEWLSGVNEYIKSNYELLETWVNKYNKIKLMKMESSYLAWMDISGL
                     GISASEFTDKLAIDTGVLLEDGSHFVKDGEKYVRINLGTQKENVIEALNRMDLFLKSL
                     "
     gene            complement(38235..39293)
                     /locus_tag="OE968_001176"
     CDS             complement(38235..39293)
                     /locus_tag="OE968_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HCP7218466.1"
                     /translation="MNKKKITFIFVILILALILFSFFRSSSQNTKYSKTSYYLGTVNE
                     VTVFNVKESKSDKILNECDSILRYIDNKMSTHIPGSDVSKINDNAGKKFVRVSDDTFF
                     VVKEAIQYSKLSDGYFDITIGPLSNLWAIGTDKAKVPSDSKIQKLLPLIDYKNIILDE
                     KNKSIKLTKENMKIDLGAIAKGYAADKIVAYLKSEDVKKGLVNLGGNIFTLENGKNDK
                     PFKIGIQDPTSKNGESIGNIETTNKSVVTSGIYERFIEKDGKIYHHMLNPFTGYPFEN
                     NLSSVTIISDKSINCDALSTSTFGLGLEKGMNLINKIDNVDAIFITKDKKVYLTKGIK
                     DNFKLTDKSFSIEKLNKQ"
     gene            39360..39731
                     /locus_tag="OE968_001177"
     CDS             39360..39731
                     /locus_tag="OE968_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HCP7218467.1"
                     /translation="MKKKDILLILGILVVITACYGIINVINSKNAGNIEIYVDNKLYK
                     TVSINAKEEFKIESRGGYNIVKIHDKGVEIVDASCPDKVCVHTGFINKPSQSIVCIPN
                     RVSIKINTNEKNDNQEDIISK"
     gene            39768..40442
                     /locus_tag="OE968_001178"
     CDS             39768..40442
                     /locus_tag="OE968_001178"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HCP7218468.1"
                     /translation="MVNLGNDWDELLKEEFEKDYYLNLRKFLIEEYKTRQIFPNMHNI
                     YEALKHTSYKDTKVLILGQDPYHGDNQAHGLAFSVQPQVKTPPSLLNMYKELKDDLGC
                     FIPNNGYLMPWADQGVLLLNTALTVRAHEANSHKNKGWEIFTDRVISILSEREDPVIF
                     VLWGSNARKKVELIDTSKHYILEAPHPSPLSASKGFFGCKHFSKINEILKKLGKEPIN
                     WQIENI"
     gene            40692..41531
                     /locus_tag="OE968_001179"
     CDS             40692..41531
                     /locus_tag="OE968_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HCP7218469.1"
                     /translation="MNFKKLSNAKVSVMAVVLSVGILSGYSALNKQVTLVVRGEERTI
                     STFSSNVGDLLESQNISYDSNDIVTLDENTKLSNGDKIEVIDVKEKTVVETKDIPFEV
                     TVVEDGSLLKGDSKVKEEGKSGKSELIYKETYHNGKKVEKEFVKKVVKAEPVNKVVSK
                     GTKVEMQVASSRGESSRRMASSSSSSSSSNNGKNMRVVATAYTGHSITATGTKPKWGT
                     IAVDPKVIPYGTKVYIPQFDMVFTAEDCGGAIKGNKIDIYMNDSKTVYNWGRKTIDIR
                     ILK"
     gene            41775..41871
                     /locus_tag="OE968_001180"
     tRNA            41775..41871
                     /locus_tag="OE968_001180"
                     /product="tRNA-Sec"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:41809..41811,aa:Sec,seq:tca)
     gene            42026..42733
                     /locus_tag="OE968_001181"
     CDS             42026..42733
                     /locus_tag="OE968_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA threonylcarbamoyladenosine dehydratase"
                     /protein_id="HCP7218470.1"
                     /translation="MENNFTTRTSFLVGDDGIKKLNNSNIIVFGVGGVGSFTVEALAR
                     AGVGNITIVDFDDVDITNINRQIPALHSTVGRYKVDVMEERILDINPNINIKKIRSLY
                     NKDTSDEILTERYDYVVDAIDMVSSKIHLIETCEKKGLKIISSMGMGNKLDPTKIVVT
                     DIHKTSTCPLAKVMRKELRDRGIKKLKVVYSTEQPIELKKKVMNGRKVTPGSVSFVPS
                     VGGLIIASVIVNELLGQ"
     gene            complement(42875..43711)
                     /locus_tag="OE968_001182"
     CDS             complement(42875..43711)
                     /locus_tag="OE968_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HCP7218471.1"
                     /translation="MRNKIFLSILIIISLLIGCDKKSLLSIHMIDVGQGDSILVQTPT
                     NKNILIDGGDEDSENIIISYLRQKRIKTIDIIIATHPDSDHIGSLDNIIKKFNVNSIY
                     MPEQSTDSKAYQNLINSCTDKNLSIQHLYKNDVLNIDNNINIYVLSPSYIQEESNLNS
                     IVFKLTFNDNSFLFMGDAEEENEKEILHSFKLNNINFIKIGHHGSNSSSSLEFIKKIS
                     PDIAAISCGYKNQYGHPHREVINNLKQNHVSIYRTDRIGDIVFYSDGEIIFTKYNYEI
                     DT"
     gene            43899..44804
                     /locus_tag="OE968_001183"
     CDS             43899..44804
                     /locus_tag="OE968_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2156 domain-containing protein"
                     /protein_id="HCP7218472.1"
                     /translation="MFFKDIELNSKKELDPYFDLVDYEACEYCFSTLYMWQHVYKTGY
                     YIGEDFAVLVGEYEGDSFSILPLAKKDKLPEVVDFVLEYFSKNNKKIYLRGITTEVVE
                     FLKEKYPGRFEYIEERDLFDYIYDAESLRTLAGKKNQKKRNHINYFLKEYAGRYEAKL
                     LDKENFDECLVLMKEWESNKEENNEFDESMDDELIGIKKIFNHYDILKDKVKVFGVYV
                     DGKLEAFSIGELLNPNMALIHIEKANPDIRGLYPFINQQFLVSEFKDVEFVNREEDLG
                     IEGLRKAKLSYHPCRFVEKYSVREA"
     gene            44813..>45960
                     /locus_tag="OE968_001184"
     CDS             44813..>45960
                     /locus_tag="OE968_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCP7218473.1"
                     /translation="MEIRYAKEEEIESIKDIWSYCFNDTESFMKYYFNDKYKSENTVV
                     ALDEGKIISSLQLNQYKLLLNSKVYNTSYVVGVSTLPEGRGAGYMNKVMKFTLNELYK
                     KGQLVSILMPIDYRLYRRFGYEHCYDQIEYTINTDDLKNFKSSGKMIKSNLSQIDDLI
                     QIDRTFLNEVNGNVLKDEHYYENLFKEIQSEDGFLYIHEGNEKDGYIVYFLQEDKMFV
                     RELFYKNIDALKSMLKFIYNHNTQCKIVTISTPTIDKIRFILDNPKDSDIKIKPFMMG
                     RVINVKKFIEDIDIEKDINSSFNLLIEDKFIDENNGLFKISIQNKKVSVEQLDKKGAE
                     KPQEDFDIKLDINTLTQLSFSYIDVNEAIFLNDIKDVSEETLETLNCI"
BASE COUNT        18044 a         4994 c         7907 g        15015 t
ORIGIN      
        1 aattttgaat aaaaataaag taaaactttc ttttatattg aagttgttta gtaagatatg
       61 tattttatta atttattaat cttaataatg ttaaataaaa tcaaaaaaat agattttggg
      121 taaataaaat aatataaaat ataaatttta ataaaaataa taaagtatat attattgctt
      181 taataagaat gtaaaaaata tttttaaatt atcatttaat gtaatttaaa tgaattgaag
      241 atatatgttt attgtatgca attgttgtat ttttaggttt tttgtgatta attaaaaaat
      301 tataaaaatc gtttacatgt tgatttttaa aaaaaaaaga tatagaatta tatagaaagt
      361 aataaacaaa aattggattt acgggagtgg aatgaaatga tgaatgttac cttaacagat
      421 gtaaaagagg ctagagagac cattaagaac atagtaaaaa gaactgactt acttgaaagt
      481 gttaaactta gcgaaaaaac aggagcaaat gtgttctata aatgtgagaa tcttcaaaaa
      541 acaggttctt ttaaattaag aggagcttgt aacaaaatag cgagtttaac agatgaagaa
      601 aaggcaaatg gagttatagc ttcaagtgca gggaatcatg ctcaaggagt tgcattggga
      661 gcaaaaatga ctggtataaa atctacaata gtaatgccag caactgcgcc tttagcaaaa
      721 gttagtgcaa ctaaaggtta tggagcagaa gtagttttaa atggtgcggt ttatgatgat
      781 gcatatgcaa aagctgttga aatacaaaaa gaaacaggag caactttctt acatccattc
      841 aatgataagt atgttatagc aggacaagga actatatctc ttgaaatttt cgaacaatta
      901 gacaataaag ttgatactat actatgccca gttggtggag gaggaatcat ctctggtgtt
      961 gctgttgcag caaaagcatt aaatcctaat gtaaaaatag tcggtgttca aactgcaaat
     1021 ataccttcaa tgaaagagtc aataaaaaat ggaaaagtaa caacagcatt taatgatact
     1081 acaatagctg atggtatagc tgttaaaact ccaggagatt taacttttga aataataaat
     1141 gaattggttg atgaaatagt agtggttgaa gagacagaaa ttgcagaatc aatattattt
     1201 atgatggaaa gtcaaaaaat agtttcagaa ggtgctggtg ctgtatgtac agctgctata
     1261 ttaagtggta agtatgtacc agcaaaagat gaaaatgtag tttgtataat atctggtggt
     1321 aatatagaca taaatacgtt atatagaata ataggtgttg ctttagctaa agaaggaaga
     1381 agatattcat ttagtacaat tatggaagat aagccaggaa actttgctga gttaactaga
     1441 ataataagtg agaatggtgg aaacatttta agtgctaatc aaggtaaatt atcagcaggg
     1501 gaagctctag gaaaacaaag tgcggaattt atattagaga caatagatta tgaccatata
     1561 gctagaataa agaaagctat agaagaaaaa ggttttaaaa ttatagaatt ataataaaaa
     1621 gtgtatataa tatacaagaa aaatagtata atagtgtatg aagatacatt ttatgtgtat
     1681 tagattaacg aattaggagg attttaaaat gaaacatgaa gtaatacata ctaatgatgc
     1741 accagcagct ttaggaccat attctcaagc tataaaagct ggaaacttgt tatttgtatc
     1801 tggacaagtt cctcttgtac cagagactat ggaagtagtt gaaggagatg tacaagctca
     1861 aactgctcaa tctttaaaaa atcttaaagc tatattagct gaaagtggag ctgatttttc
     1921 aaatgtagtt aagactacag tatttataaa agatatgaat gaatttgggg ctataaacga
     1981 agtttatgct gaatattttg gagaaaataa accagcaaga gcttgtgtag aagttgctag
     2041 attaccaaaa gacgttaaag ttgaaataga agtaatagct gtattataaa aatacaatat
     2101 ttttaatttg aaaaggctga aaaactatat tctagtgatt cagccttttt ataaaaaaat
     2161 aaatcacaat aaagaacatg ataaatattg tcgaattaaa aaataaaatt aaaataaata
     2221 ttgcaatatt tttgagaagg ttttataatg agtatataat ttgaaacgtg taactattaa
     2281 attaggcatg agttcttgga tatttttatc ctgaggattc atgccttttt tgtattgaaa
     2341 ttcaaaaatc tatttaataa ggaggaagta ctgtgttaaa ttttttcaag aaaaataaaa
     2401 gctataagtt acatgcagta gtgagtggta acagcattaa tattgagaaa gtaaacgatt
     2461 ctgtgttttc aaaaaagtta atgggagatg gagttgcaat tattcctaat agtaatgttg
     2521 ttgtagcccc ttgtaatggt aaagtaactg tgcttacaga atcaaagcat gcctttggta
     2581 tggtctcaga tgagggtgtt gaaatattag tccacatagg aattgataca gttagtttac
     2641 agggtgaggg gtttaaaaat gaagtgtctc aaggagatac tgttaaaaaa ggtagtccaa
     2701 taataagttt tgaaagagaa aaaataaatt ctcagggaat tgattgtaca acaataataa
     2761 ttgtattaaa tcatagcgaa ttttcagaaa taaattgcat ggtagaaaat gaagttgttg
     2821 cagggcaaga tactgttatt gaaattatga aataatagaa agggattaat tcaatatgag
     2881 agtagtaaaa atctttaata ataatgcatt atctacagta actaatgata ggaaagaagc
     2941 tattttacta ggtcttggta taggttttaa taaacgtcca ggagataaag ttaatgaaga
     3001 taaaatagaa aagatttatt atgttcaaga ccacatgcaa acaaaatttt tagaattatt
     3061 aaaaaatgtt agtccagaag tgatggatgc ttcacaacaa attataagtc ttataccagg
     3121 aaatgaggga aaatttaata ataaagggat attatcttta gtggaacata ttagttttgc
     3181 aatagataga atgaaaaata atgttttttt acctaattta atgcttttgg atataaagat
     3241 gatgtattca aaagagtttg aattaggagt aaaagcttta gaaattatat atagagtatg
     3301 tcatatccat ttgcctgaag atgaagcagg ttacatagct ttacattttg tcaatttaca
     3361 atcaaatgat aatttggcat atgatacttt aaaatttgta aaaggtagta ttgatttgat
     3421 taaagaatgt tatggattag aattagacga atcgagttta agtacattac gttttagaac
     3481 tcatcttaaa tttcttgctc aaagaatttt taagaatgaa atttgtcagg atgataaaat
     3541 gattgaaatg tatgattatt taattaacaa tcatcctaaa aataaagaat atttagaaaa
     3601 gttaaatgta tatattgaaa aggagtttag gtataaatta gataaacctg aaaaaattta
     3661 tctactacta cacctaacaa aaatcttata agaatgagat gaattagtaa tagaaatata
     3721 tataatttta gggggggata agattgaaag aaaaactact tggaggactg gaaacatttg
     3781 caaaggcaat ggttcagcca ttaatgtatt tatcgagtgc aggaatatta atggtggtag
     3841 gtgtactact tacaaatgat atgttattag gagtacttcc attttttaaa tgggagccaa
     3901 ttcaaatatt tggaagccta atttataact gtataatggc tattattaat aatcttgctg
     3961 ttatatttgc tataggtatt cctgctgcac tagcaaaaaa agagaagcac aaagcagcgt
     4021 taataggatt tatgagttat ataatatacc ttacagcttc caacactatg ttaacatcac
     4081 taggtcaact agcaaaagaa agcaagatgc ttggactgat agggactgga caagctacta
     4141 ttttaggtat tcaagttgta gatacaagtg tatttggtgg aattatttta gggtatatag
     4201 ctggatatgt atttaatcgt acaagcaaca aaacatttaa aggagcttta cagatatact
     4261 cgggagcaaa ttttagtttt atatgcatgt tctttgtatc cattttaatt ggagttgtga
     4321 gtaactttat atggccatta gctcaacaag gaatagcttc tcttgcaaat gtcatcaaag
     4381 atacaggtac atttggttta ttcttatatg gttttttaga gagaatatta gtaccaactg
     4441 gacttcatca tttaatttat acaccatttc agttttctga tttaggagga gtgcttaaag
     4501 ttggtgcaga tacagtttca ggagcctatg ctatagttat gacagaaatg aatttaccag
     4561 ttgagcgttt ctcagatagt atatactaca tggcaactgg atttacaaag atgtttggtt
     4621 atataggtat aggagctgcc tttatttata ctgcatataa gcaaaataag aagaaggtta
     4681 aggcaacgat tattccacta ataattacgg cagtattagc ctctgtaaca gaaccattag
     4741 actttatgtt tgtattctgt gcaccacttt tattctttgt acatgcagtt atagctggtc
     4801 tttttatagc tttattaaaa atatttgatg ttactgcatt atgtggaggg aacttattag
     4861 tatcagttat aatgaatact acagtaggcg tagaaaaaac acactggcca gtaatgatga
     4921 tattaggact tgcacaaatt attgtatatt ttgtagtatt tagtttttta attaagaaat
     4981 ttaattataa aactccaggt cgtgaagatg agagtacagc tacaggcgaa gaacaatcaa
     5041 aacaacttaa tttagatgca gggatagaaa atataattga tgggttaggc ggaaaagaaa
     5101 atattaatac agtagaaaat tgcatcacta gattacgtgt taatgtaaaa gatgaaagta
     5161 agattaatga agatataatt aatttaacgc caaatagcgg gattgtaagg aaaggaaaag
     5221 atatacaaat aatttttgga cttcatgtgc atgaggtaag acgtgcagta gaagattttt
     5281 tagaagctta ttaaagatat atatttatat agcaagggta aataacagct ttaagtgctg
     5341 tttactattt attaaagata catataattt atagaggagg aataattatt atgattatta
     5401 ctattgttgg tggaggaagc acatttactc caggtattgt taagtcaatt gcattaagag
     5461 aaaaagagtt agagcttgag gaaattcgtt tatttgatat tgataaaaaa cgtcaagata
     5521 aagtagctgt agttgtcaac tggatactaa aagaagatgt taaaacagat gttaaactaa
     5581 ctgtaactaa ttgtgaaaaa gaagcgtata cagatgctac atttatattt gcacaaatgc
     5641 gtgttggtaa atatgaaatg cgtgagcagg atgaaaaaat tccattgaaa tatggttgtg
     5701 taggtcaaga aacttgtggt tgtggaggga tggcatacgg actgcgtaca atacaaccaa
     5761 tgataaaggt tattgatgat gtagagaaat atgctaaaaa agattattgg atattaaatt
     5821 actctaatcc tgctgcaatc gtttctgaag cttgtcgtaa gttaagacca aatgcaagga
     5881 ttataaatat ctgtgatatg ccaatagcta ttatagatat gatagcgggg tcattaaata
     5941 tcaatgacgt tcataatata cgctatgatt attttggtct aaatcatttt ggctggttta
     6001 cttcaataga ttataaacat agagacttaa tggaagagat taaggaatac ataaaagaaa
     6061 ataaaatatt attaccaaaa tcttatatag aaaacttaaa taaaagtcgt agtacaggaa
     6121 atcgccatgc tgtaagtagc tggatacatg tttgggaatc tgtttataca atgttagaaa
     6181 gcttcccaaa atatctgcca aacacttatt taacatacta tcttttaagt aaagaaacag
     6241 tggaacattc aaacataaat cgtactcgtg caaatgaggt tatggaaagc cgtgaaaaag
     6301 acttatttga aggtgtgaga cattacttag aaactggaga aatttctgaa aaagcatttt
     6361 atgcaggttc acatggagat tggattagtg atttggcagt ttcaattaaa aatgatacac
     6421 gtagtcgttt tttagttata actgaaaatc gtggagctat accaaacatg ccatatgatg
     6481 caatggtaga aattccagca tatattggta aagatggtcc agaagttatt gctcgaggtc
     6541 caatacctct atttcaacaa ggattaatga tgcaacaact taacagtgaa aaattgatag
     6601 tagaagctta tatagaaaat agttatgaaa aagctttaca agcattcaca ttaaataaaa
     6661 ctattccaag tatgaatgtt gctaaagaaa ttttggatga aatgatagaa gttaataagg
     6721 aatactggcc agaattaaga tagtaggata aaagaaaggg tttttattta atcattagat
     6781 atgttttcag agtcttttat caaaatgtat tcacaaacat atggcaatat attaaaataa
     6841 agagtgatat ttttagaaga atggggtgat gcaatgaaca ttataaataa aattttttgg
     6901 caagaagata ggattggcat gattacaaat aatttagagg cagatacaca tagccactgt
     6961 atgttacaac tgttcttagg gatagaagac agcattgaaa taacagttaa tgaaaaatta
     7021 gttaaatgta attgtatcat agtagataaa aatatctctc attcattttc agcaagaaaa
     7081 aaagtttatt actctgctat tattgaacct acatctatat atgcagaaca gcttacctca
     7141 aaaatgaatg attttggcta ctggatatgt gacaatgatg gattagagaa attacgtcaa
     7201 caaggaactt ttttgatatc taactctagt aaagaacaat atttaagatt tatggaaatg
     7261 cttaataact atttgaatat acctataact ctcaaacatt atgatgacag aattactgaa
     7321 ttgttcaatt tattacatac ttgtaattgt gataatcata ctatttcaag ttttgcagat
     7381 aaagtgtctc tatcagcaag tagattatca catctgttta aagaacaaat agggatacct
     7441 ttaaaaagct atatcttatt tcatcaaatg gagtgtgctt ttagagaatt actttctgga
     7501 aaaaatgtta ccgaagcttc tatgactgct ggattcgata ctccatcaca ctttgcaggg
     7561 acagttaagc gaatgatggg aatgcctgtt tctttatctt tgaaagatag cgagtttttg
     7621 aaagtatatt aaatattctc gttatataat gaagttgtac taagaaaggg gctttgttat
     7681 gaataaagaa tatttagaag aaacaaaaat gttaaattat aatgaaccac aacttaagct
     7741 tttggtatca tcaaagaatt ggttggaatt agatgatttt cataaaataa aatctattta
     7801 tgagtttgta cagaatgata ttttatttgg atataatgct tctgatatgt taagcgcaac
     7861 acaggtatta aatgatggta tgggacaatg caatacaaaa gctactcttt taatggcatt
     7921 attacgtgca gtgaatatcc cttgtaggct tcatgctttt gatgtaacaa aagattttca
     7981 acgaggagct acatccaaat tgatttcact attagcacca aaatatattc ttcatacttg
     8041 ggtagaggta ttttatcaag ataggtggat tgctctggag ggtgtcataa ctgataaaaa
     8101 atatttagaa gcaattcaga agaaattttt taatcatggt ggaacgttta aaaagtatgc
     8161 aatagctaca aatgatttga aaaatacatc tattgattgg gatggtaaag atacttttat
     8221 ccaaaaagaa gctatcgtgt atgattatgg tatttttcca tcaccagacg tatttttttc
     8281 tactcattca caacatatgt caaaattaaa aaatttcata tatgtacatc ttatcagaaa
     8341 aataatgaca aaaaatgtat gtaaggctag aaacaattat attgataaaa atgaatgagt
     8401 gtttaagagg taactatata ggaaatatat agaataatta aaactgtact ggttaaaatg
     8461 aataaaaagg agttatcaca gagcaaactt aaattgttca taggataact ccttttctgt
     8521 attaacttct aataatttga tgtcttttta taaaacatat agatacaatt aaaccagtaa
     8581 atgcaagagt agctgctatt gaaaatgcaa catctattcc atgaatgtta gacagcatgt
     8641 ttgaactcat atgagctttc ttagtagcac ttgtcattat agtaataagt atagcagaac
     8701 ctatagctcc agatatctga cggagtgtgt tattaattgc tgtggcatga gatataagtt
     8761 ctctatctaa tgttttaatt ccccatgtag ttaatggcat taaaaccatt gaaataccaa
     8821 tcatacgaat acaatacatc aatgacacat gaattaaaga tgtatctctg cctaaaaaag
     8881 cgaaggataa agttcctaaa aacaaacatc ctgttcctaa tattgataga gcatgaggtc
     8941 catatttatc taaatgacgt cctgcaattg gattgagtac aaccatcaat atagcaccag
     9001 gtaacattaa tgaacctgaa gataatgcag aaaatcctct tacagattga acgtacagag
     9061 gaatcattaa tgtagcagac atcattgagg catatacaat cataattaat attgtagaaa
     9121 taagaaatgg tttattttta aaaaccctca attctaaaaa aggttcttta gattttaatt
     9181 gacgcaatgt aaataaaatt aatgacataa ttcctattaa tattggtaaa tatgtggcaa
     9241 tattagtcca cccataatta ccttgattag taaatccaat taataaacca ccaaaaccta
     9301 gagatgatag tactattgaa ggtatatcta attttagttt ttgagtttcc ccaacatttc
     9361 ttaataaaat aaatgatagt ataacatcta atatagcaat aggggaaaga aacagaaata
     9421 aactatgcca accaaatgaa tctactaacc atcctgataa agttggacct attgctggag
     9481 caaatcctac tgtaatacca actaaactca tagctgcacc acgtttttcc tcagggcata
     9541 aatagagtat aataacttgt aaaagtggca ttagagaacc agaacccatt gcctgcaaca
     9601 cacgagcaat caacatagtt gaaaaattat tagaaaaaag tgcaataata catcctatag
     9661 aaaagataga cattgatgta ataaataact ttctagtact aaatcgattt attaaataag
     9721 ctgttgtggg tacaataata cctgcaataa gtagataaat tgttgttaac cactgaccaa
     9781 catcagcagt aattttaaaa tctgacatta tattaggtaa tgctgttgac aatagtgttt
     9841 gactgagaga acttataaaa gcaccagtca ttacaattgc tattattaaa tttccttttt
     9901 tattgttact ttgggtttcc ataatttata acgtctcctt ttttaattga tttttaatgc
     9961 tgttcaataa aagtactttt ggtcttaaag tgtcttcttt ttctaaatat gcaatcattg
    10021 catccataat taaagaatca tattgttgat tttttccctc gacgtataat ttttttattg
    10081 cttctagtaa tttaggattt tcaaggagag aagtatcagt tttgattagt tcttctatat
    10141 cttgtatcat tttaaaaaat agcgatttat tatgaaggga aaagtaaact tcatcttctt
    10201 gtttatgtaa aaacattgat ttttcaatta aaggatttag attatccata ttttctacaa
    10261 ctaaatctag aatttgtata gtaaatttgg caataaagta tacatttatt tctctttttt
    10321 gtacatgaat aatgtatata aactgatgaa ttagagcatc caataagaaa actaaatcaa
    10381 atataatttt ttctatttta tcaccatagt tatcaaataa gcttaatttg tattcattca
    10441 ataagttagc tcgtgatttt gtttgcaatt tacttgtagc cttacgttgc tcttcagaaa
    10501 aattttctct tatataggta tttatggtag ttctagaaaa aatatttttc catacagcaa
    10561 ttatctttct gtttaacttt tctgatgctg gaatgtcatt attttcattt atggaatgta
    10621 taatttctaa aaacttttca tcataataat tgattatttc gcagataaaa ctttccttag
    10681 tttcaaaatg cttgtaaaaa gtagctttag acattttaca ctcttttaca acatccgata
    10741 ttgaagtatt ttgaaaaccc ttttggtcaa aaattttttg tgcaatagtt ataatgagcc
    10801 tttgtttttc tgtcacttta ttatctcctt tcacgcaaaa acgtttagta ctatagagta
    10861 cctacaagtt ttaataaata tattatacat catttggaaa aaaaatcaat atatagactg
    10921 taatatgaaa tttttgaaaa atttgttgtt atttttagtc gtataaaaaa gaaacttaag
    10981 agtttcttaa gaattgttta aagaagttgc aataaattag tggtatgatt atagtatgaa
    11041 agagaatgtc ttgaaatttt tctgtatcaa attccaatta tggaggtgta gtatatgaaa
    11101 aagaaaattt gtgtagcaat aatttttgct ctatttatag tttttgtaga aatgtttatt
    11161 gatagctcta gcgaaggaag taaaattatg acagctgaat taagtaaata caggaaaggc
    11221 gtaaatgtat tatcaataaa caatattata gtagcgaata aaaaatatag tttgcccaaa
    11281 gattattctc ctcaggaaag cagtgaagcg agagatgctt tttataaaat gaataaagat
    11341 gctcaaaagt caggattaaa tttaaaagct tttagtacat atagaagtta tgaatatcaa
    11401 gatagattat ttaagtcata tgtaaaagaa catggagaaa aagaagcaaa tagattttca
    11461 gctaaacctg gagagagtga gcatcaaact ggacttgctt ttgatattgg aggagatgac
    11521 cagtcttgtt gggcaaataa aaagttcaac aatacaaaag aagctaagtg gttgtatgaa
    11581 aatgcatata aatatggttt tatacttaga tatccagaag gtaaagagaa tataacagga
    11641 tatatgtatg aatcttggca ctatagatat gttggaactg aacatagcaa aaactttgca
    11701 atgaataatt tgactttaga agaatattta catataaatt aagagatggt ttgttaaaat
    11761 taggttaaaa taaaaaataa cctagactat tagctgtgta aagtgatata atgtaaatac
    11821 aatttagata actactcgaa ggggagtagc ttacacgaaa gtggtaatta atcgtcaaga
    11881 cagtagaaat actcggttaa ttagcaaggg attccttgat agcaagacct tcaaaataag
    11941 cattaggtat gtttgttttg gggtcttttt ttattcaagg aatttttatt taaaaaaatt
    12001 taaatttcaa gtatacataa gagcccccaa acataaaata aatttattga agaggagggc
    12061 aacaaatgtc ttacaaaagt acttatcaag aagtaattaa aaatttagac tcaagtttat
    12121 ctggtttgag taaagaaaga gcagaagagt tgttagaaaa aaatggagct aatgaattaa
    12181 aagaagcaga taaggttcct acttataagc ttttcctaga aagttttaaa gacccattag
    12241 taataattct attgatagct gctttagtac aaatattttt aggtgaaaca gtggagtcta
    12301 taataatttt tgcagttatt attataaact ctgttctggg tgttgtacaa acaaaaaaag
    12361 cagaaagttc attagaaagt ttgaaaaatt tatctgcacc aaacgcaaag gtaataagag
    12421 acaataaaaa aatgacaatt ccagcaaaaa atctagtagt tggagatatt gtattcttag
    12481 aagctggcga ttacatacca gcagatggaa ggcttataga agcacaatct ctcaaggttg
    12541 tagaagggat gttaactgga gaatcagaac cagttttaaa gcatacagaa aaaataagtg
    12601 aagatgtaag tttaggtgac cagaaaaata tggtatttag tggtgctgta gttgtttatg
    12661 gtagaggttc ttttgtagtg actggaacag gtatggatac tgaaatgggt aaaatagctg
    12721 ggcttttaga aagtgctgaa aataaactta caccattgca acaaaaaata gaggatttta
    12781 gtaaaaaact tggtgtaggt attgtaatac ttgctctttt aatatttata attcaagtag
    12841 caagaaatta ctttatggct ggaaatggag aaatgacaca aattatttta gattcattca
    12901 tgttctctgt agcagtagca gtagcagcta taccagaagc tctatcatca atagtcacta
    12961 tagtattggc tgttggaaca aatagtatgg caaaaaaaca agccataata agaaaattac
    13021 cagcagtaga aactttaggt tcaacaagtg taatatgtac tgataaaaca ggtactctta
    13081 cacaaaataa aatgacagta gttgattatt atatgtatgg aactaataat gatgagttag
    13141 ataaagaaaa agtaaactat tcttatcatg ctaaattatt gactatggtt tctacattgt
    13201 gtaatgactc tcatataact agtgatggta aagaagttgg tgacccaaca gaagtagctt
    13261 taataaatta ttcaagtaaa aatgatttag attatgataa attaagaagt aagtatatca
    13321 gaataaatga aataccattt gactcagaca gaaagcttat gtctactgta aatagtatat
    13381 atggagatta tataatgttt acaaaaggtg ctccagatat tgtgtttagt agatgtaaat
    13441 atgctttgaa aaatggttca aaagtagata taacagatga gataatagaa gaatataaac
    13501 ataaaaatga agagttttca aatagagcac ttagagtatt agcttttgca ataaaagatg
    13561 tcccagaaga agattttata ccttcaattg atgacgaaca tgacatgaca ttggttggaa
    13621 taatggcaat gatagaccca ccaagagaag aagtaatgga tgcagtaaaa gaggcaaaga
    13681 gtgctggtat aaaaactgtt atgataactg gtgaccataa aacaacagca gcagcaattg
    13741 caaaagagat tggtataatg gaagaaggag acttggctct tactggaaaa gagcttgatg
    13801 ctttgagtga agaacaacta tatgaaaaac tagaaaatat aagtgtatat gccagagtct
    13861 cgccagaaaa taaaattcgt atagtaaaag catggcaaca taagaataat ataacagcaa
    13921 tgactggtga tggtgttaat gatgcacctg cattaaaaca agcagatata ggaatcggta
    13981 tgggaagtgg tactgatgta gcaaaagatg cttctgctat ggtattggtt gatgataact
    14041 ttgcaagtat agtaaatgct gttgaagttg gtagaacagt atacagtaat ataataaaat
    14101 caattactta tctatttgca ggaaacttag gagctatagt atccatagta tttgcagtgt
    14161 ttgcaggttg gtcaaatcca tttacagctt tacaactttt gtttataaac ttagtaaatg
    14221 actctttacc agcaattgca ttagggtttg aaaagtcaga aaaaaatata atgaataaac
    14281 ctcctagaca cccggatgaa agtatactag caggaggaac attgaaggca gttgctataa
    14341 gaggttgtat aataggtgta gttacaataa ttgcacaata tataggatta caagtatctc
    14401 cagaacttgg agtagcaatg gcattttcaa cattgatatt agctagaata atgcaaacat
    14461 tacctgcacg ttctaataat caaacagtaa taaaattagg ttttttcagc aataaatacg
    14521 ttataggagc agttttagtc tgtcttgggc tttactcttt aacactaata ccagtgctaa
    14581 gaggaatatt ctctatacca acaacgtttg gattgtacca gttggggatt tgcctagggt
    14641 tagcattaat ttcatcaata ttaatggaac ttaacaaatt aataaataga agtgaagtaa
    14701 aataatcaaa aaattaaagg gcatattgat tttaacaata tgccttttat aaatagtcta
    14761 atttattcta tattatcgat tatttggaat gcttttataa cttcaggtaa ttctttttct
    14821 tcaggcattc taaatcttat gaaattttta tcaagtccag taaaatcact tccagatata
    14881 actcttattt ttaatttagc aaactcttgt tgtaaatcta tgtccttgtt tttatgttca
    14941 actgtcataa ttgatacagt atcactagtt tcagctatat taaggttttt ccatggaatt
    15001 aataattgat tttttatatc ttttgttttt tcttttaatt cttctataaa ttgaacatca
    15061 tctaataaat ttgctgcaat actacgagat atttcagaca cttcgtaagg agtagaaatc
    15121 tttttaatag ggctaacaag ttgttctgga agaactgcat atcctgctct tagtcctgct
    15181 aaaccgaatc cttttgaaaa tgtttttaaa gcaattacat tatcataatt atttagaagc
    15241 ttgacagctg aattttcttt tggcatgtat tcaccataag cttcatctac cataactgct
    15301 atatcatatt tagctgcttc ctttactata ttttcaattg atgataaatg tataatttgt
    15361 cctgtaggat tgtttggatt gtctatgtaa attactttat attctggatt tattttttca
    15421 ataaattctt tttcattaaa cttgaaatta tcctctttct ttaaaagaac ataatcataa
    15481 gttgcaccat gcatttttat atctgtctca tattctgaga actgaggtga atatcctaaa
    15541 actttatctc ccttttcaat aaatagtcta tttaaaaggt aaataacatg tatagaacca
    15601 tctgccaaac aaattctgtc agtatctaat gctataaaat ctttccaata atcgactata
    15661 ttatctttta aagcaattga atgaggatat cctcttatca tatcaaattt taaagcatta
    15721 aaagcttcta cagctttgtt tgagtaagac acggtattta taccttcacc acagtctatc
    15781 tcgaatacat cttctgaatg tccagattct attgcataac tttttttcaa ctgcatttca
    15841 atagctttgt taatttttag tttcatactt tatcactcct tatttagtca ataataaatg
    15901 ttataaaagt tgctagattt aaaatattat gaaaatatat aatagtaaaa aatgaatata
    15961 aatattataa tagctcactt tatttaatat gattatatat catatattgt aaaatttcta
    16021 gcattataag actataaatt gaaaatattc agaaaaatac tacaagaaac gatttatttt
    16081 gctcttaaaa taagttaaat gaatgttatt aattttgtaa attgaaatag tttaagtata
    16141 aagttatgat ataatctaat aagggtaatt ctttagatta tattaaggaa atataggtat
    16201 acaataaaaa gttatggagt tggattatgg gatataaatt aattgtaaca gatatggatg
    16261 gaactttatt aggcaataat cataaagtta cagatgaaaa taaaactgca ctacaaaaag
    16321 ttataaaaag cggtattaat gtaactttag caacaggaag agccttcgat tcagctaaat
    16381 gcaatgtaga ttttcttaaa gaggacatgc caataatagc ttgtaatggt tcattaataa
    16441 gagagcaaaa tggaaatata atatattcaa ataagattga tacaagaaca tgtttaaaca
    16501 ttttagatgt attagataaa tacgatattt actaccaatg taatagtata gattctatgc
    16561 tttcgaaaaa aatagaagga cgtgaagata gattaagtgt atttttaggc tctgaaacag
    16621 aagtaattgt aaaagatgat ttgagagaag aaatctttaa aaaagatata ctaaaatttg
    16681 taatcataga agaaaaaaat ccatctattt tagatgaaat aagaaaagaa ttgagaaaag
    16741 ttcaaggaat aaagataact tcttcatggc caaacaatat tgaagtcatg aatgaaggtg
    16801 ttgataaagg taatgcagtt aaaattttag ctgaaaaaat gaatatagac agagaagata
    16861 taattgcatt tggagacaat tacaatgaca tagaaatgat aaagtttgct ggtcttgggg
    16921 tagctatggg aaatgcagaa gaattgatta aacaagaagc tgattatgtt acagatacaa
    16981 atcaagacag tggagttgca aaggcaattt ataaattcct agagttaaaa gaatcactta
    17041 gctcttaaaa cagtatataa taggaaaaaa taggttgact attttgtaga tagtaattat
    17101 aatacaaata gataaaacat aaaaatttag attcagtgaa aaagagagta gatatagaga
    17161 aaatctcagc gaattggggg atggtgtgag cctaatgata acactttata ttgaaaagaa
    17221 ctttggagaa tactacttga aattcagtat ggtagtaggt aatctcgcct taagagaata
    17281 gagtgggtaa acattgttta ccaactagag tggtaacacg gaatatttcg tctcttggtc
    17341 tttttgacca agagattttt tagtttcatt gagttacaag acttataatt aaaatacaaa
    17401 aaattaaaat atgaggtgaa agttatgaaa ttatggggcg gacgctttag aaaagcggaa
    17461 aatcaactta tggaagaatt taataaatct tttggctatg attgtgtact gtacaaaaaa
    17521 gatatcgaag gaagtgtagc acatgttcat atgcaagtaa aatgtggact tttaacagaa
    17581 gaagaaggaa agtctataac agaaggttta aaagggatac ttgaagatgt agaaaatgga
    17641 aagttagtat tggatggaga gtatgaagat atacatagtt ttactgagat aaatttaatt
    17701 caaagaattg gagatgttgg caagaagctt catacagcac gtagtagaaa tgaccaagtt
    17761 gcagttgata tgagattgta tgctaaagaa aaagcaaatg atttggtggg tttaatatct
    17821 gaatttaaag ctactataaa agatgttgct gacaaaaacc cagtgatgat gccaggctat
    17881 actcatcttc aaagagctca agtagtgaca tttaagcatc acttaatggc atattatagt
    17941 atgtttgata gagatgagaa aagaataaaa aatgctatag aaatattaga tgaatcacct
    18001 ttaggctgtg gagctttagc aggaactacg catgatatag atagaagtat aacttgtgaa
    18061 caattaggat ttaaaaaagt agtagataat tttatggatg gagtaagtga tagagattat
    18121 ttactagagc taatgagtga tttttcaatt ataatgatgc acttaagtag attaagtgaa
    18181 gagttgatac tttggagttc tcaagaattt ggatttgttg agatagatga tttatataca
    18241 actggaagta gtataatgcc tcagaagaaa aatccagatg gtgcagagct tataagaggt
    18301 aagactggca gagtatatgg aaacttattt ggtcttttta cagtaatgaa aggaatacca
    18361 ttagcatata ataaagacat gcaagaagat aaagaaggtt ttttcgatag tgtacatact
    18421 cttgaaatgt gtatacaaat aatggataga atgatagcca cactaaaggt aaatgaggat
    18481 aaaatgaaac aagcagtaaa aaatggtttt ttaaatgcaa cagaagttgc ggattatttg
    18541 gttaaaaata atgttgcttt tagagatgca catggtatag taggaagtat cgttatatat
    18601 tgtgaagata ataaaaaagc aatagaagat ttaacattag aagaattaca taagttttca
    18661 gatgctttta aggaagatat ttatgatttt atcgactatg agagtatatt aaataaggga
    18721 ataaaaaaga atttaaaata atgtatttat ttttaaaagc tgtaaatttg aatgttatca
    18781 tttaaattta cagcttttta ttgtgtaaga ttttattata taaaagtaag aaacttaaaa
    18841 gtagtagtat ttaaaataaa tacaaataaa aaattgttat taaaatgata attaatatca
    18901 ataagtattg acaaaattat ttctaaatac tattatatat aatataaata ataatgaaaa
    18961 tcaatatcaa ataaatggga ggaaatctaa tgaacttatt agtgattggt ggtcatgaaa
    19021 gaatggaaaa agattatatg gttatggcca agaaaaaagg ttataagaca aaggtatata
    19081 ctaccatgtc atctaaatta aataattcta taggaagacc agatgcagtt gtcatactta
    19141 catcaactgt ttcacataag atgtctagaa cggttgagtc tcaagctaaa aaacaagata
    19201 tattaatcgt aaggcataaa aatagtagta aggtagcatt taatgaatgt ctagatatgg
    19261 ttgatgaatg tctgggaaat tgttcaaaat gtaagcttaa agacaaacaa aaacaaaaaa
    19321 atatataggt ataaaaaata cataaacata aaattaaaag tactgagata atagttataa
    19381 ttattatctc agtactttta gatttataag gataagtata ttataaattt tttattataa
    19441 tttccaacta cttgttactt tttcatattt tttttacttc tagctttttt tctttttttc
    19501 ttctttatat ttgaagctat tataaataaa actaaaagca ctagaatacc tgcaataatc
    19561 ttaacaaaag tcattaaaat attatttcca gtaaaaaatg gaagactgct atcaagatta
    19621 ttttttgcaa ttaagtctat actgttttct agtttaccat tattatatac atttaaagta
    19681 ccaaccttag cccctttttt tataggcaaa tcaattttat ttaactctgt tttggtatca
    19741 taattgcctt gagattcatc tttttctaag aatatcctat aactattttt tggttcataa
    19801 atcaattcat gttgttttgt aaacaatact tttttagtat ctgtgtattt ttctttatca
    19861 acaatagtag cacacttaaa gttatcaaat ccataatcaa tcagaatacg tgagtctaaa
    19921 tataaatcag cattagttga attaaataca gcaacgataa ctcttctgcc atcttttaca
    19981 gcactcgata aaagacattt accagcagca tcagtatatc cagtttttat accatcaact
    20041 atatcatatt ttatatttat aggttgacct ttgtatgtaa tcttatcatg tgatgtcaaa
    20101 aacttattag tgtttacaaa gtatctctca taaggatatg cttttgtagc ttcaaattta
    20161 agtgacttag tttttacaat ttgtctaaaa gtatcattat tcatagcttc tctagctatg
    20221 agagccatat catgagctgt tgtgtagtga tttgggtctg gtaatccatg aggattatta
    20281 aaatgagtat tagtagctcc aatttttttt gcctcagagt tcataaggtc aataaatttt
    20341 tgtacattgc caccaccaac atatctagct aatacaaaag cagcatcatt agcagaatga
    20401 accaaaagag catctagtaa ctgctttaca gtaaaagatt ccccattttt tagatacata
    20461 ctagagccat ctatttgagg taaatcttta atttctatta cttgatttaa atctttaacc
    20521 tcctttagaa ctaaacaagc tgtccatact ttagttgttg aagctggata aagcttagaa
    20581 tttccatcct tattatatag tattttgcca gactcatagt ccattaaaac tgcatgttta
    20641 gcaactatag ctggttcatt atctgcaaaa gagatattag agcttcctaa aaatgaagta
    20701 aatatcaata aacagattaa taaaagtgat aaatttcttt tcattgtgag cctccaaatt
    20761 ttaaattcat cttttagtat agcatatatt tgtcaataat taaaagaaag gagtgattaa
    20821 tatatgaaaa aaaaagtaaa atttatttcg ttttttgttt tatttatttt aataatatca
    20881 tcaataatcg tttataaatc gcttattttc aaagatgata tttatgttgt aagtaaaaaa
    20941 aatttaccta atgaaaaaac acatgttgta gagaatgaaa ttaaaggtga agataataat
    21001 cacaataaag taactaaaga catagataaa aattttcaaa ataataaaat aactatatac
    21061 ataagtggag cagtaaatag acctggaatt gtaactatag agtcagacaa gagactttat
    21121 gatgctgtag aattactagg aggaacgaca aaagaagcag atttaaatgg agtcaatcta
    21181 tcagtaagat tagaagatga acaacattac ataataccca aaataggtga agcaacatct
    21241 gttacaagta atgatgattc caataaacca aatcagagga atgagtcaag aggtgagcct
    21301 aaaaataaat ccaataaaaa tatatctaac gaatcaaaag taaatataaa tgtagcgact
    21361 atagaagagt tggattctct acctggggtt ggagaagcta cagccaataa aattttacaa
    21421 cacagagaag aaaatggaca gttcagttca attgaggaaa taaaaaatgt aaatggtatt
    21481 ggagataaaa agtatgaaaa tataaaagat ttaatttgtg tagactaaaa tataatacaa
    21541 aacttacata tagatatgtt attataaata tgtatgtata tgtgtgtaca tgtggaaatt
    21601 tagtaaagga ggcactttta tgaaaaaaga acaaaaaaaa cttacagaga tgacaacagc
    21661 aggtggttga gccgctaaaa tagggccaga ggttctggca tcagttttat ctcaattgcc
    21721 taaaaatgat aatatagaaa atttattagt aggactagat acagcagatg atgctgcagt
    21781 ttataaatta aatgatgata tggcacttat ccaaacttta gacttcttta caccaatggt
    21841 agatgaccca tacgtatttg gtcaaattgc tgcatcaaat tcactatcag atgtatatgc
    21901 tatgggaggc aaacctttgg ttgctatgaa tattgtttgt tttccatcat gccatgatat
    21961 ggatgtactt gcagaaatat taaaaggtgg gtttgataaa gtgaaagaaa gtggagcact
    22021 tttggttgga gggcatactg tagatgacaa agagcctaaa tatggtcttt cagtttctgg
    22081 gattgtaagt ccaaataaag ttttatcaaa tgctactgca aaacctggtg ataagttaat
    22141 tataacaaaa ccaattggag tgggtgtatt aaatacagcc atgaaagaag gtatggtaga
    22201 acaacatata gcagataaag taatagaaat aatgatacat ttaaataaat atgcagcaat
    22261 gagttttgag aaatttgatg taaattcggt tacagatata actggttttg gtctacttgg
    22321 tcatacttta gaaatggcca aagcttctga agtaagtatt gaaattgaat caaaacatgt
    22381 accaattatt gaaggtgcaa tagaaatggc acaaatggga attatacctg ctggtatgta
    22441 taaaaatatg cattatgtat ctaaagatgt agaagttgta ggaaatatag aagttgcagt
    22501 tcaagatatt ttatacgacc cacaaacatc aggagggttg ttaatttcag taaaagaaga
    22561 acttgcagag gaacttgtaa aagatatgaa attaaatgga gcaatagaag ctaaaattat
    22621 aggttctgta gttccaaaag gggaaaaata tattacagtt ttataaaata ttatagagaa
    22681 agagtgattg ttttgagcaa aagagaattg tttgcaatgt tgccttcagt tgatgaagta
    22741 ttaagtgata atagaattgt agaaataata aatgaatatc ctagaagttt agttttagaa
    22801 tctgtgagag aagtaataga tttaaaaaga caatttatat taagattaaa agaagatgca
    22861 tcaaactctg taacaataga gtttggtgaa ataatagaat ctgcaataga gagagttaag
    22921 ttaaattact cattatcttt aaaaaaagtt ataaatgcaa ctggtacagt tattcataca
    22981 aatttaggaa ggtctttact tagtgaagat ataaaagatg aattatggtg tgctgcttca
    23041 aggtattcaa acttagaata cgatttggat aatggagaaa gaggttcaag atactctcat
    23101 ttaactagta caataaaaag acttactgga gcagaagatg tactagttgt aaataataat
    23161 gcagcggcag tacttcttgt acttagcaca atggctaaag gaggagaagc aattgtatct
    23221 cgtggagaat tagttgaagt aggtggttca tttaggattc caagtataat ggctcttagt
    23281 ggtgcagaat tagttgaagt tggttcaact aataaaactc atttgaaaga ttacaaggag
    23341 gccattacag aagatacaaa tgtattgatg aaggttcata caagtaatta tagaataatg
    23401 ggattcacag agagtgtttc tatagaagaa ttggttaatt taggtaaaaa atataaacta
    23461 cctgtaatag aagacttagg aagtggagtt tttatagatt tatcaaaata tggtttatct
    23521 tatgaaccaa ctgtattgga ttctattcga caaggtgcag atgtagtaac ttttagtgga
    23581 gataagatgc ttggaggtcc gcaagcaggt attatagttg ggaaaaaaga gtatatagaa
    23641 aaaatgaaga aaaatcaact tactagagca cttagagttg ataagcttac aatatgtgct
    23701 cttgaagcaa cattgagaat gtatttagat gagacaaaag ctatagaaaa tatacctact
    23761 ttaaaaatgt tgacatataa aattgaagaa ttagaagtaa aagcaaataa actatttgaa
    23821 aaaataactg ctttaaactt aaatgcaaac ataaatatag aagatggatt ttcacaggtg
    23881 ggaggagggt ctatgcctct tgaaactata agtacaaagg taatatcaat aactcctgaa
    23941 catatgaatg tttcatcttt agaaaaaaaa ctaagactta gtgaagcaca tataatagcc
    24001 agagtgtatg ataataaata tgtactagat gtaagaacta tatttgatga tgaatttgat
    24061 gtaatagttg aggaattgag aaaagcattt aattaaataa atttgagtta ataaatatta
    24121 aatttagaag tataagtatg aagttttgat taaaaaatag ctacacacac ttgtgacttt
    24181 agtcatagca ggtttagagg gggcaaaaaa tgaaaaatgt agtaattgga acagcaggtc
    24241 atattgacca cggaaaaact actcttataa aagcattgac tggaagagag actgatacgt
    24301 tagatgaaga aaaaaagaga ggtatttcaa taaacttagg atttacttat tttgatttac
    24361 caaacaatag aagagctgga attgttgatg tcccaggaca cgaaaaattt ataaaaaaca
    24421 tgttagctgg agcatcagga attgatatag ttttacttgt tgtagcagca gatgaagggg
    24481 ttatgccaca gacagttgag catttagata ttctaagctt tttaaatatc aaaaatggaa
    24541 tagtggttct aactaagtct gatactgtag atgatgaatt tagagagcta gtaaaagaag
    24601 atatttgtga aaaaataaaa ggaacttttc ttgaagatgc tgaaataatt gaagttgatt
    24661 ctatatctaa aagaggtata gacactctta ttgaaaaaat agataaaatg agtgatgata
    24721 tagaagataa aaatgaaaac tctccagcaa gacttaatat agacagagta ttttcaataa
    24781 aagggtttgg tactgtaata acaggcactt taatagaagg aaagataagt atagaagatg
    24841 atttggttat atatccacag gtattaaaaa caaaaataag aagtatacaa gttcatggag
    24901 aaaataaaga tacagcttat gcaggtcaaa gaacagcaat caatatatca aatgtaaaag
    24961 tggatgatat aaaaagagga gatgttttag ctgcaccaaa ctcattggag gaatcaatga
    25021 tgttagatgt aaaattatca ttggtaaatc atttagataa aggattaaag cactgggata
    25081 gattaagatt gtatcatgga actagagaga tactttgtag agcagttcca ctagataaag
    25141 aattaattga aagtggagaa agtggctatg ttcagttgag acttgaagaa agcatagtat
    25201 ctaagaaagg tgatacgttt gtagtgagac gttattctcc aatggaaact ataggtggag
    25261 gtgtaataat tgacccatct cctaaaaaac ataagaaatt tgatgaaaaa gttatagaag
    25321 cattaaaaat aaaagaaaaa ggcgaactaa aagatataat agaagagtac ttaaaaagga
    25381 atttaaaaaa ttatccaaat ataaaagaaa taatgagcta tagtggtgct catgaagaag
    25441 atgtaaaaag agcgcttgaa acacttatat cagaagataa agtatttatt ataggaaata
    25501 tgtatatgca tataaatcaa tacaataaat taaaagaaaa tacaataaag cttttaagtg
    25561 agtaccataa gaagtatagg cttagaaaag ggatactaaa agaagaagta aggtctaaga
    25621 tagagagtaa ttttaagact agggagatgg atattttatt agaaaaattg tctacagaaa
    25681 atgctataaa aatagaaaat aatatagtat ctctattaga ttttgaggtt attttaaatg
    25741 ataagcaaaa agaaatagca aaaaaaatag aaaaaagatt aaaatcatgt ggagtttctt
    25801 ctatactgac aatagatgaa gtttctgaag gaaatcataa ctatgctgaa gtattggagt
    25861 caatgatagg taataaagta gagaaattag atgatttgta tataatggac aaagatattt
    25921 atgaaaatgc aaagaacatt ttgataaatt atataaaaga aaataaagaa ataacattag
    25981 gagaatacag agatttgatt gattctagca gaaagaattg catgattata ttggaaaact
    26041 tcgatagaaa caaaataact aaaagagtag aaaacaaaag aattttgttt tagcagaaaa
    26101 tgtctgtttt tgctttaagg tataaagaag gaattataat gtcgagtatc gtataattaa
    26161 ttagtataaa atattaatta agaggaagtg taaagtattg aagaatataa tacctgatgt
    26221 aaaaccagat ataaaagaaa gagaagacat gagcctttta tttataataa tgggctcagt
    26281 acttttatta tttattataa aagatataga gaaatatgaa actttattac atgccatata
    26341 tacgatattt ttagtagcta caggagtaat tatatttaat actacaaaat ttaaagtaga
    26401 ttcattttct acatttttag gattaatttt tatagctact ggagtattgg agtgtatata
    26461 tttatttaat tccttgggga ttaaaactaa gtctataatg gagattaaca tcacaatatc
    26521 agcaataaca gatttatttc ctatactggg tgtatactta agttttaaat ttgttaagga
    26581 taacaaacaa atttattcaa gtgtaatttt atttatagca actgctacat taacaataac
    26641 atctttattc ataatatcag gaatttgtga ctatctggga aatggtaaat cacaatatgc
    26701 tttaggagtt ataatatcta tattcataat aattatttct atcattagtg gaattgaatt
    26761 aaattcaagt tcaaataaag gtaaatggga atatgatgaa aaaaagattt ttaacagaat
    26821 aatagtaata ataatcttat caagagttcc aaatctattg catatagtta ttgataatag
    26881 aaatgtagag aggatattat cacaaataat aataaatgta gccttatatt atttatataa
    26941 ttacatagta tctaagaata ttaagaaaac agcactggaa ttgcatgata cgaatgaaga
    27001 attaacaaaa aaaacggaaa gtttaaaaga aaagaataaa aaattaatct atgagacaga
    27061 aaagatagag gaacttaagg gaatacttat gaaaagagaa tctaggctac aatctacatt
    27121 agatgtagca gtaaatagca tagtagtatt tagcaaagat ggagaaatta catatgcaaa
    27181 taagagcttt agaaatactt ttggagacta taaagaacaa gataaattga ctgataaaat
    27241 aaaaaacttc aatgatttga tagaaagcat tcattatgtg tttgttcatg agaagaatgc
    27301 agagaaactt attagtacaa gcgataataa agtttatcaa gctatatttg cacctttaat
    27361 tattgcttca caaacagaag gagtattgtg tgtactagaa gataagacta agaaaaagga
    27421 gtacgaacgc aaacttattg aagcaaataa gagaagtaaa gattttttag aaagtattgg
    27481 agatggcata gtagtgcttg aaggtaataa caaaatatat gttaataatg catgtaggga
    27541 aatttttaaa aataatttag agagtattga tttttcatta gtatgtaaaa gtgaagaaag
    27601 tatagaaaaa agatatgtaa tagatggtga agtaaagtat gtagagatga gtttttctca
    27661 gtatactaat gctggtacta ataaaactat tattgtaata cgtgatacaa cctctcgaaa
    27721 aatatctcaa ataaaacttg aggaaagtca atcatcatat tcaagattta tagatatatt
    27781 acctgatggc atatgcttat taaaagaaga tttaagtata aactatgcaa ataagtcgtt
    27841 tttagatatg ctagctttta caaacataga tgatataaaa gattctaata ttaaactatt
    27901 aatgaatgcg aatactgaag aaaaaatgaa atttacggat aatatggcta aagttttaaa
    27961 tgaaaataga agtatacttt tactggaata tgaattgata aatagttatg atgatatagt
    28021 agaagtagaa ttaagtgcat taccttttgc tatatacaat actagataca taatgcttat
    28081 tataaaagat ttagtacata agaaatattc cgagcaagca gaaaaagaac tgcttgaaag
    28141 atttaaaaca gataaaatca aaacggagtt ttttgcaaat atgtctcatg aactaaaaac
    28201 tccactaaat gttatatcta gttcaaatca actggtagat tctttctata gaaatgaaaa
    28261 gataaaagat tacaataaca atattaaatc tcatgtggat ttagttagac aaagttctta
    28321 taggcttcaa agattaataa ataacattat agatttaaca aagatggagt ctgggttcta
    28381 tacactaaaa cttgcgaaat acaatattgt atctgtaata gaagacttat ttatgaatat
    28441 agaagagtat gcacttagaa aagacataaa aattcttttt gatacagacc ttgaagaaat
    28501 taatgtttat atagacaagg ttgaaattga gagaattatg ttgaatctat tgtcaaactg
    28561 tattaagttt actgataatg gaggctggat atatgtaagt attcattata aaatagataa
    28621 agtaatcata agtgtaaaag acactggagt tggaatacca caagataaat tagagttgat
    28681 ttttgaagaa ttttcacaag ttgataagac tttatccaga aatactgaag gaagtggaat
    28741 agggcttgct atagttaaga atctagtaag tcttcatggt ggagatatag aagtagtaag
    28801 tgaagtgaat aaaggcacag agttcttaat ttcacttcca atgaagggat ttagtagtga
    28861 acattacaca gaagataaga gaatatataa tattcaagaa aaaataaaaa tagaattttc
    28921 tgatatatat tattaaaaat gattatgagc aaaaataaaa taaaaatact atttgtttaa
    28981 atatttaagt tgtaagaaat aggctatcat aaggtaaatt attatgatag cctattttta
    29041 gctaggtttt atatctatat gtgagaacat ataatctcta aattaccttc aaaactaaaa
    29101 tctccaaagt cgtttggtag tataaaatgc ataccctttt ttaaattgta ttctacagaa
    29161 ttgtgtataa gttttccatt tccatccaac acactgtata aagaaaaagg tgtattgtgt
    29221 gtaaaattac attttccaaa aacatctaat ttataaacac taaaaaattc gtttgacaca
    29281 aatgttgtgc atttaaagtc tgatgttgat acgattttat agtcagtatc gaaatttata
    29341 tgaggaacat tcgtaacatc tattgatttt tgaacatgaa gttcacgctt attacctgaa
    29401 ttgtcagttc tatcataatc atagactcta taagtagtat ctgagttttg ttgagtttct
    29461 aaaatcaatg ttcctttgca tatagcatgt atagtgccac ttggaacata gaaaaagtct
    29521 ccctttttta tattaacctt tctaagtagt ttgtcccatt cattattatt taccatattt
    29581 acaaattctt tatgagattt tgcattatga cctattataa tttctgcatc atcagaacaa
    29641 tctattacat accaacactc tgtcttacct aactctccat tttcattttt tttagcatat
    29701 tcatcatttg gatgaacttg aactgataaa ttatcatttg catccaatat ttttgtaagt
    29761 aaaggaaact tatcaccagg tgtgtttcca aataattctc tatttttatt ccacaattca
    29821 gatagttttt tacctttata ttttccattt tctattaagc aatctccatt tttatgagag
    29881 cttatagccc aacattcacc agttgttggc gaatctattt cataattaaa tttatcttta
    29941 agtgcagtac caccccatat tctatccata aaaataggtt ttaaaaataa tggttccata
    30001 atcctgttcc tcctatgata ttaaatttat cctacaaata attatatata aatagattat
    30061 aaaatcaata gtaaaaaagt tttgtccctt gaaatgacat aaagtataag gagttattaa
    30121 ataagataaa ctatgatata taatataaag ttctaaattg gagtgataat tatggagttg
    30181 tttaaggcag aaagcaaaaa atataaaaaa gaatttttaa aattattgga gcaatgggtt
    30241 agtatacctt cattttatga tagaaaaact gtatctaaag acatgccttt tggaaaagga
    30301 gtatatgatg cattaaactg gtttgaaaat ctaggtagag aaaacaattt caaagtaaaa
    30361 aatatagata atcatgctgt tcaaattgaa tatggaaatg gtaaagagta tgtagatata
    30421 tttggacatt gtgatgttgt aaatccaggt gaaggatggg atagtgaacc atttaaacta
    30481 aatattatag gtgataaatt agttgctaga ggtgtatctg ataataaagg gcctatgata
    30541 gtgaattttt tagcactaaa aatgataaag gatttagata ttaatttaaa aagaaaggtt
    30601 agattaatag ctgggggaaa tgaagagagt ggatttaaat gtataaagca ttattatagc
    30661 aaagagccat atggtgtatg tggatttact ccagatgcta aatttcctgt attaaatgga
    30721 gaaaaaggtg gagcaataat aaagttaatt tcaaatatag acgataaatc tttatatata
    30781 agtggtggaa tagagtttaa tacaatacca gataaagttt atataaagaa tgtagaaaaa
    30841 ttgggtaaag ataatatatg ttttgatatt aacaatatat cgataaatta tgataatggc
    30901 aattatattg tgtatggaaa aggtggtcat tcatctaaac ccgaaaaatc aataaatcct
    30961 atattagcta caattaaact tttgtcagaa aatattgatg aaaaatggac aaaagattta
    31021 tataagttga taaatcaaga taatataaat ggaaacttat ttggtttaaa tattgagggg
    31081 aaatgtggaa ttttatcaat ggtgccaaca ataataaata tagtagatgg aaaattagaa
    31141 gtagttttaa gcgttagata tccagaaata ttaaccattg aagatataat aaaaaaattt
    31201 aatttgtata tggagcaaaa taatattaat aaatttgagc ttattgggga aaatttaaag
    31261 caagcaaatt atatagatag aaattcaaaa cttgtaagaa gtttgcatga tatatatata
    31321 aagtattctg gagatttaaa aaatgatgtt agagtaacta gtgcaggaag ttatgcttct
    31381 gaaatgaata attcagtaat atttggttgt gaatttcctg atggtagctt tggcaatgtc
    31441 catagtgcga atgaatttgc tagcttagat agatttataa ctgcaatagg tatatatgca
    31501 gaggcaataa ttacattatg taataaaata taaatacaaa atgtccctta tatagacata
    31561 ttatatatac aattaaaatt ttacttgata tataattgaa atcaaagaga aggtgataca
    31621 atgataacta agaaacatgc aataatagta aagagtttaa gcaataaaga tggatatatg
    31681 acatcaaacg aattagctat caaattggat gtgtctacta aaactattaa aagatatata
    31741 gcagatttaa atagtgtttt aagcaaatat gatttggtaa tagcttcttc tagaggtata
    31801 ggatacaagt taagcggttc taaaaacaat atagccagag ctgttaaaga agcaaataaa
    31861 tatattgatg gttttttaga tgactctgaa gagtcaagaa tgtcaaatat aatatgtatg
    31921 cttattaata gaaattatat gagtatagaa gcaatggcag aagaattaaa tctaagtata
    31981 gccgctataa ataaattgtc tagtaagctt aaaagaaaac ttgaaaagta tgacttagtt
    32041 ataaaatcta aaccttacta tggaagctat atacatggtg aagaaattaa tataaggcaa
    32101 ttaattactg actatgcaat aaaattagat gaaaaaagta aagtgaaggt gtttttagat
    32161 gacattagtg aaaacgatat acactgtata gaaagtattt tagaaaagca cttaagagaa
    32221 aaagatacaa taatttcaga taaagatttt aatcttttgc tttcaaaaat aatcgtttct
    32281 gtatttagga gtaagagagg tcatagtaac aatataaact taatggatac aagttataga
    32341 tttcataact actactttat agaaaatcta atgaaagaaa tatctgataa aattggattt
    32401 aaacttattg aagatgaagt aatttatatt tcaaattatt ctggtgtaat agcctataaa
    32461 ggtacacaag gaagaaaaaa cacaagtgaa attgaggaac gaataagtac tgttataagt
    32521 agtgcacttc aagatatatt ccttatttca ggtagtgatt atacaaaaga tgatgagttt
    32581 atggttgcaa tctctgacca tataaagaga tttttaaata gagctagagc taatgtaaaa
    32641 tcaaataatc ctttacttca tcaaataaaa gagaagtttc ctatagcttt taatttagcc
    32701 gtgtttttat caaataaact agaaactgag tttaatttaa aacttgatga agatgagctt
    32761 ggatatatag ctatccactt tgctgcttca aatgaaagaa tgaaaaaaaa tactagtaag
    32821 aaaatttgta tagtttgtca ttatgggata ggaacaggac aacttatttc tgaaaagcta
    32881 aaacagaata taagtgattt aagtgttgtg ggtgtttatc cagttagata tctcgatatg
    32941 gctataagtc aagatgttga tttgatagta tctacagttg aattaaaagg atatgaaaaa
    33001 cctgtcttat atatagaaaa tatatttgat gatagcttaa ttgaaaacgt aaacaaagcc
    33061 ttttatgaaa aggaagaaag aagaaagata ataagtaaca tgtttgatga aaaagctttt
    33121 ttcagtataa aggctagtac taaagaagag gtcataattt cactttcaaa taaactaaaa
    33181 gaaagagatt ttatagagga aagttctata aaaagtataa tagatagaga aaatatttca
    33241 tcaactgaaa taggaaatct agtagcaata ccccacacaa tagtgaaggg agataaaaaa
    33301 tctataatag gagttggaat acttgaaaat ccaataattt gggataagca agaggttcag
    33361 ctagtattta tggtattttt taatactaaa gaaaaacata atttctcgat atttaaatac
    33421 ctttataatt ttataaaaga tgaaggagga gtaagaggaa ttattaaaat atgtgacttt
    33481 aataaattaa tggcacttat aggtaattaa ggaggaaatt aataatggga acaaacatat
    33541 ttaacaaaga atatgtattt ttaaatgttg atgctaagtc aaaggttgaa gttttaaaat
    33601 ttatatcaaa aaaagctaaa gacttaaact tggcagaaga tgagagctta gtatatgaag
    33661 gtttaatggc tagagaagaa caatttacta caaatttagg agaatctata gcaatacctc
    33721 acactaaaaa tgatgcaatt gaaaatccag cagtagtagt attgaagttt aatgaagatg
    33781 ttgtttggaa tgaaggtgag gataaggtta aattagcaat aagcttactt atgccaggaa
    33841 aaagtaaaga gaatattcat cttaaattat tatcatctct ttcaagaaaa ttaataaata
    33901 aagaatttaa agattctctt ttaaaaagtg ataatgttga agaaatatct aacttaataa
    33961 atgaagcttt aggtttataa ttaaacacta aggttataaa ataaaaaaat aattaactaa
    34021 aaataggagg aatttgaaat gaataaaaaa ttagtagcat tatgtgcttg tccaatggga
    34081 ctagctcaca ctttcatggc agcagaagca atagagcaag cagcaaaggc attaggttat
    34141 gaagcaaaag ttgaaactca aggtgctgat ggtgtacaaa atgagttaac aagagatgat
    34201 atattaggag caactatgat aatacatgca gtagcaataa caccagaagg tatggaaaga
    34261 tttgatggtt gtgaagttta tgaagttgaa ttacaagaag ctataaaaaa tgcagaaggt
    34321 gttataaaag aaatagaaga agatttagga atataataaa tttattgtgg aggaaataga
    34381 atggcaatta agaaaaaagt tataaacagt tcaggtgctt ctacaacagg aggaaataat
    34441 gtaggaaaat ctactccatc tagtccaact caatcaaagg gaaatggaaa atggaaagaa
    34501 ataagtaaac atataatgac aggtatatca tatatgatac cagttttagt aatgggtgga
    34561 cttatagggg ccttatctca attaatacca tatgctatat taggacttga cccatctgta
    34621 ggtatagttg atgctatgaa ctcaggagaa tttacagggt tcaagcttag tcttttaaat
    34681 atagcacaat taatgtcaaa tttcggattt actttgtttg gatttgcgat accactgttt
    34741 gcagcatttt gtgcaaactc tataggtgga aaaacagctt taattgcagg atttataggt
    34801 ggatatatag ctaataaacc tgtaggtgta ccacaattcg ttgatggaca atggactgaa
    34861 gttgttccag ttgcatcagg atttttaggt gcaatactaa tagcatttat aataggatat
    34921 tttgtaaaat ggttaaataa atctataaaa gtttctcata actggttagc ttttaaaaca
    34981 acatttttaa taccattaat agcgtcatta gcttgtatgg tattgatgat atttataata
    35041 actccatttg gtggattaat taatgaaagt atgaaaaact tcttaacagc agcaggagca
    35101 gctggagaat atgtatatgc aacagctttg gcagcagcta cagcattcga cttaggagga
    35161 ccaataaata aagcagcagg attcgttgca cttggtttaa ctacagagaa tgtacttcca
    35221 ataacagcaa gaacaatagc tatagttgtt cctccaattg gattaggatt aacaacatta
    35281 ttagataaaa gattagtagg aagaagagta tatgatagac aattctatca agcaggaaaa
    35341 acttctatat tcttatcatt tatgggtata tctgaaggag caataccatt tgcacttgag
    35401 agaccaggtt ttgttatacc tttaaacata gttggaagtg taataggagc tattacaggt
    35461 ataattctag gagcaattca atggttccca gagtcagcta tatgggcatg gcctctagta
    35521 gataacttat ttggatatat aataggtata gcagttggtg ctatattcat agcagtagga
    35581 aatatattct atagaaataa attaataaaa gatggtaaac ttgttgtaga ttatatcgac
    35641 tagtatttaa tttttactat ctataaataa ctttggctgg taatatggtt ttaatcaata
    35701 ttaccagcct tacctatatg attaattaaa ggcggtggag ataagatatg gataagatag
    35761 aaaaagtaag agagtatttt agagaatatg atatagatgg atttcttata aatagtccta
    35821 caaacaagtt ttatgttgga aatttattta gctcttcagg ttatgttttt ataactaaag
    35881 aatcacaata tataatagta gattttagat attttgaaga aattaaaaga aaatctagtt
    35941 tgtttaatgt agtattaatg gacaaaacta gaactcattt tgatataatt aatgatattt
    36001 gtagagagca gaatataaag gaaattggat ttgagggaaa tgaagtatct tttgatttat
    36061 atagaagtat gagtaataag ttaagtgcaa ccttaaaatc agttgattta tctacattaa
    36121 gggaaacaaa aaatgaagac gaaataaaat atataaaaaa agcttgtgaa atagttgatg
    36181 ctacatttta tcatatagta gactttataa aggttggtat gactgaaaag caagttgaaa
    36241 atgaaattgt tagaattata aaagatttag gtggtcaaaa agaatctttc gatacaatag
    36301 ttgcatctgg gcttagagga gcattacctc atggaaaagc aagtgaaaaa gttatagagt
    36361 atggagattt tgttaccttt gactttggtg ctaagtataa taattattgt tcagatatta
    36421 ccagaaccat ttgtatgggt actataaata aagagttaga agaaatatat aatatagtaa
    36481 gaaaagctaa tgaagagtgt ataagggttt taagaccggg aatgactact ggagagatag
    36541 ataaagttgc aagagacata attggttcat atggatatgc caataatttt ggtcataatc
    36601 tgggtcatgg tgtaggaatt atggttcatg aatatcctgc attagctcct gaatcaaatg
    36661 aagtattaaa agaaggaatg attgtaacta tagagcctgg tatatatgtt ccaagtcttg
    36721 gaggcgtaag aatagaagat gatgtactta taacacaaga tggatgtatg agattgacta
    36781 catctactaa ggatttaata gttgtaagct aaaaataaat tagataaata ttttataaca
    36841 ataagaaaag aagaggtaaa tttaaatgta taattttgat gataaaccag atagagtaag
    36901 tgaaaagtgt agaaaatggg atttaaatat tataagagat aaatttggag atattagaga
    36961 agattttata ccaatgtgga ttgctgatat ggattttaaa ataccaacag aaatagaaaa
    37021 caaatttatt gaagctgtaa gaagaggtgt atttggatat acatactgtt atgatgaatt
    37081 ttatgattca gttattggtt ggcaaaaaaa tatgcatgag gtaaatgtag aaaaagaatg
    37141 gattacatta acttatggaa ctgtatcaac acttcattat gtagtacaag ctttttgtaa
    37201 gaaaggtgat agtataatat taaatacacc agtttatgac ccctttgaat catcagcaaa
    37261 aaaacaaggt gtaaatgtaa tttgtaatac attagatgtt gtaaatgata gatattatat
    37321 aaattttgat aaattagaag ttcaaattaa agaaaataag cctaaattaa tgatgttttg
    37381 tacaccacat aatccatctg gaaggatatg gacaattgaa gaaatgacaa gggtagcaac
    37441 tatatgtaaa gaaaataatg ttattttggt tgcagatgaa gtacatgcag agcatattca
    37501 ttatggtaca tttaattcaa tacttaagat tggaaaagag cttttagaaa atgttattct
    37561 attgacatca ccaaataaag gatttaatct tggtggatta aagacttctt attcaatagt
    37621 tataaataag gatataaggg acaaatttag aaataaatta aagcaaaatt ctataacttc
    37681 tccaaatgtg tttggaataa taggattgat aaccgcttat aatgaatgtc atgagtggtt
    37741 aagtggtgta aatgaatata taaaatcaaa ttatgaactt ttagaaactt gggtaaataa
    37801 atataataag ataaaattga tgaaaatgga atcatcttac ttagcttgga tggatataag
    37861 tggattaggt attagtgcaa gtgagtttac agataaattg gctatagata caggagtatt
    37921 attagaagat ggaagtcatt ttgtaaaaga tggtgagaag tatgttagaa taaatttagg
    37981 aactcaaaag gaaaatgtaa ttgaagcctt aaatagaatg gatttatttt taaagtcttt
    38041 ataaaaattt ggttgaatta gtattttata taaatttaaa ctattaatat ggtatataca
    38101 taagtagaat ttgttttaga ttacttaagt atataccata ttttatataa aaattaaatt
    38161 tgcattagtc atgtgataac tatttaaatt catatgtatt ttgtatgtat aatagatata
    38221 attattattt aaacttattg tttatttaat ttttcaatag aaaaagattt atctgtaagt
    38281 ttaaaattat cttttatacc cttagttaag tatactttct tatccttagt tatgaatata
    38341 gcatctacat tatcaatttt attaattaaa ttcatacctt tttcaagacc aagaccaaat
    38401 gtagaagtgg ataaggcatc acaattaata gatttatcag agattattgt aacactactt
    38461 aaattgtttt caaaaggata ccctgtaaat ggatttaaca tatgatgata tatttttccg
    38521 tctttttcga taaatctttc ataaattcca gaagtaacaa cagacttatt tgtagtttct
    38581 atgtttccta tggattcacc atttttacta gttgggtctt gaatacctat tttaaaaggt
    38641 ttatcatttt taccattttc taaagtaaat atatttcctc ctaagtttac taaacctttt
    38701 tttacatcct ctgattttaa ataggctaca attttatcag cagcatatcc tttagctatg
    38761 gcacctaaat caattttcat attttctttg gttaatttta tagatttatt tttttcatcc
    38821 aatatgatgt tcttataatc aataagaggc agaagttttt gtatcttaga atcacttgga
    38881 actttagctt tatctgttcc aatagcccat aaatttgata atggaccaat tgttatgtca
    38941 aaatatccat ctgataattt ggaatattgt atagcttctt ttacgacgaa aaatgtatca
    39001 tcagaaactc tgacaaattt tttaccagca ttatcattta ttttagaaac atcacttcct
    39061 ggtatatgag tgctcatttt gttgtcaata tatcttaaaa ttgaatcaca ttcatttaag
    39121 attttatcac ttttggattc ttttacatta aatacagtaa cttcgtttac tgtaccaagg
    39181 tagtagctag ttttactata tttagtattc tggcttgaac tcctaaaaaa tgaaaataaa
    39241 attaatgcta aaatcaatat cacaaaaata aatgtgattt ttttcttatt catggtatat
    39301 tcctcctatg aaattgtgtt attattttat tataacataa tttcatagga ggacaaaaaa
    39361 tgaagaaaaa agacattctt cttattttag gcattttggt tgttattaca gcatgttatg
    39421 ggataataaa tgttataaat tctaaaaatg ctggaaatat tgagatttat gtagataata
    39481 aattgtataa aactgtttca ataaatgcca aagaagaatt taaaatagag agtagagggg
    39541 ggtataacat agtaaagatt catgataaag gggttgagat agtagatgct tcatgccctg
    39601 ataaggtttg cgtacatact ggatttataa acaagccaag tcaaagcata gtttgtatac
    39661 ctaatagagt gagcataaaa ataaatacaa atgaaaagaa tgataatcaa gaagatataa
    39721 tttctaaata aaataataaa aataattgaa aggaattggt gataattatg gttaacttag
    39781 gaaacgattg ggatgaatta ttgaaagaag aatttgaaaa agattactac ttaaacttaa
    39841 gaaaatttct tatagaagaa tataaaacac gccaaatttt cccaaatatg cacaatatat
    39901 atgaagcttt aaaacacact tcatacaaag acacaaaagt cttaatatta ggacaagacc
    39961 cttatcatgg agataatcaa gctcatggtt tagctttttc agttcaacca caagtgaaaa
    40021 ctccaccatc tttattaaat atgtataaag aattaaaaga tgatttaggt tgttttatac
    40081 ctaataatgg atatttaatg ccttgggcag accaaggagt gttactttta aatactgctc
    40141 ttactgttag agcgcatgaa gctaattctc ataagaacaa aggatgggaa attttcactg
    40201 atagagtaat atctatttta agtgagcgtg aagacccagt tatttttgta ctatggggaa
    40261 gtaatgcacg taaaaaagta gagttgattg atacaagtaa acattatatt ttggaagcac
    40321 ctcatccaag cccattgtca gcaagtaaag gcttttttgg atgtaaacac ttctctaaga
    40381 taaatgaaat tttgaaaaag ctaggaaaag aacctattaa ttggcagata gaaaatatat
    40441 aaaagtaaaa ggtaacaaaa tgataacaaa acaacaataa acaatgacat tgttgtaact
    40501 aatagaaata tgcttaaata gttgaaaata ctatgtatgc atatttctat tttttttgtc
    40561 aagttgacaa ctcttgaaaa aatagttaca atttagttac acaaaaaaca caaataaaaa
    40621 aagaaactta caaagcagaa ttttatgaag caaaatatat agtgtaaaaa atcttaggga
    40681 ggaaatttta tatgaatttt aaaaaattga gtaatgctaa agtctcggta atggcagttg
    40741 ttttatcagt tggaatatta tcgggatact ctgcgcttaa taaacaagta acattagtag
    40801 taaggggaga agaaagaact atatcaacat ttagttctaa tgtaggagac cttttagaat
    40861 ctcaaaacat tagctatgat tcaaatgata tagtaacttt agatgaaaat acaaagttat
    40921 ctaatggaga taaaatagaa gtaattgatg taaaggaaaa aacagttgta gaaactaaag
    40981 acattccatt tgaagttaca gttgttgaag atggctcttt attaaagggt gattctaagg
    41041 ttaaagaaga aggaaagtct ggtaaaagtg aattaatata taaagaaact tatcacaatg
    41101 gaaagaaagt agaaaaggaa tttgtgaaaa aggttgttaa agctgagcca gtaaataagg
    41161 ttgtaagcaa agggacaaag gtagaaatgc aagtagcctc atcaagggga gaaagttcaa
    41221 gaagaatggc ttcatcatca tctagtagca gtagtagtaa caatggtaaa aatatgagag
    41281 tggtagcaac tgcatatact ggtcacagta taactgcaac aggaacaaaa cctaagtggg
    41341 gaacaatagc tgtagaccct aaggttatac catatggaac taaagtttat atacctcaat
    41401 ttgacatggt gtttactgca gaagactgtg gtggagcaat aaaaggaaat aaaattgata
    41461 tctacatgaa tgattcaaaa acagtttata actggggaag aaaaactata gatatacgta
    41521 tattaaaata gttaaataat ttatattttt actggaaatt atattttgat tatatagaga
    41581 agaaactctt tatagattct aaaaatataa tttccagttt tttattttgg atatgtaata
    41641 aaacaggtaa attttaacca tgtatagata aaagctattt aaattataat ttactatcat
    41701 ataaatctat aaaaattgtt gcaaagagtc aaaatatatg atattataga tttcgttgag
    41761 aaggatttca ttatgggagt ggatgggtgc cggtgtgccc tctagtcttc aaaactagta
    41821 tgaggggtta agagcctctt aggtgggttc gattcccacg cattcccgcc aatatgtaaa
    41881 aggtatcttt taattaaaag ataccttttt aaatttattt taagataatt tatttttaat
    41941 aatatataat gttttgtatt atataatgta aattttctaa tacaaaacat tatatattta
    42001 gataaaaatc taggagtgtg gaaagatgga aaataatttt acaacgagaa ctagttttct
    42061 agttggagat gatgggataa aaaaacttaa taattcaaat ataatagtat ttggagttgg
    42121 aggagttggt agttttactg ttgaagcttt agcaagagct ggagtaggca atattactat
    42181 tgtagatttt gatgatgtag atataaccaa tataaataga caaataccag ccctacattc
    42241 aactgtagga agatacaaag ttgatgtcat ggaagaaaga atattagata taaatcctaa
    42301 tatcaatata aaaaaaataa gaagtcttta taataaagat actagtgacg aaatactaac
    42361 tgaaagatat gattatgttg tggatgcgat agacatggta agttccaaaa tacatctaat
    42421 tgaaacttgt gaaaaaaaag gattgaaaat aataagttct atgggtatgg gaaataaatt
    42481 agacccaact aaaatagtcg ttacagatat acacaaaaca agtacttgtc ctctagctaa
    42541 agttatgagg aaagaactta gggatagagg tatcaaaaag ttaaaagtag tatattctac
    42601 tgaacaacca atagaactta agaagaaagt aatgaatggt agaaaagtaa cacctggtag
    42661 tgtatcattt gtcccatctg taggaggttt aataatcgca tctgtaatag taaatgaact
    42721 attaggacaa taagttttaa atattttaat ttataaattt tatatacaaa tttgaaggct
    42781 agaagcatga atacaaagca attttatatt catactttta gcctaattat tttatattac
    42841 cttattttat gtagttgtag ttttattttt tagattatgt atctatttca taattatatt
    42901 ttgtaaatat aatttctcca tcactataaa aaacaatatc tcctattcta tctgttctat
    42961 aaattgatac atggttttgt tttagattat taataacctc cctatgtgga tgaccatatt
    43021 gatttttata tccacatgat attgcagcta tatctggact aatttttttt ataaattcta
    43081 aagatgaaga agaattactt ccatgatgac ctatttttat aaaattaata ttatttaatt
    43141 taaaagaatg taaaatttct ttttcatttt cttcttcagc atcacccata aataaaaaag
    43201 aattatcatt aaaagttaat ttgaaaacta tagaatttaa attagattct tcttgtatat
    43261 atgatggact taatacatat atatttatat tgttatctat gtttaaaaca tcatttttat
    43321 agagatgctg aatagataag tttttatccg tacaagaatt tattagattt tgataagcct
    43381 tactatcagt tgattgttca ggcatatata tggagtttac attaaatttt tttataatat
    43441 tatcaagact tcctatgtgg tctgaatctg gatgagttgc tattataata tcaatagttt
    43501 ttattctttt ttgtctaaga taactaataa ttatattttc gctatcttca tcacctccat
    43561 caattaatat attcttattt gtgggtgttt gaactaaaat actatcacct tgtccaacat
    43621 caatcatatg tatagatagt agagattttt tgtcacagcc gattaaaagt gatattataa
    43681 taagtattga taaaaaaatt ttatttctca ataaaaaatc actccattca ttacatgttt
    43741 atataaattt atgatgggta atataagata tatatgactt attatatttt atattttaaa
    43801 caatataaat gaaattaata ccataataaa attggagttt tttatatata caaaataaaa
    43861 tttttaaaat taagcaataa aaaaggtagg aggattttat gtttttcaaa gatattgaac
    43921 taaattcaaa aaaagagtta gacccatatt ttgatttagt agattatgaa gcttgtgagt
    43981 actgttttag tactttatat atgtggcaac atgtttataa gacaggatat tatataggtg
    44041 aagattttgc cgttttagtt ggggaatacg aaggagatag cttctcaata ttaccacttg
    44101 ctaaaaaaga taaacttcca gaagttgtag attttgtcct tgaatatttt tctaaaaata
    44161 ataaaaaaat atacttaaga ggtattacta ctgaagtagt agagttttta aaagaaaaat
    44221 atccaggtag atttgagtat atagaagaaa gagatttatt tgactatatt tatgatgcag
    44281 aaagtttaag aactctagct ggtaaaaaga atcaaaagaa gagaaaccat ataaactatt
    44341 tcttaaaaga gtatgcaggt agatatgaag ctaaattatt agataaagaa aactttgatg
    44401 agtgtttagt actaatgaag gaatgggaaa gtaataagga agaaaataat gaatttgatg
    44461 aaagtatgga tgatgaatta ataggtatca aaaagatatt taaccattat gacatattaa
    44521 aagataaggt aaaagtgttt ggtgtttatg tagatggaaa attagaagct tttagtatag
    44581 gagagctttt aaatccaaat atggcattga ttcatataga aaaagctaat cccgatataa
    44641 gaggtctgta tccatttata aatcaacaat ttttggtaag tgaatttaag gacgttgagt
    44701 ttgtaaatag agaagaagat ttaggtattg aaggattaag aaaagctaaa ctttcttatc
    44761 atccttgcag atttgttgaa aagtacagtg ttagggaggc ttaatagact atatggagat
    44821 taggtatgct aaagaagaag agatagaaag tataaaagat atttggagtt attgttttaa
    44881 cgatacggag agttttatga agtactattt taatgataaa tataaatctg aaaatactgt
    44941 agtagcttta gatgaaggaa aaattatttc ttctcttcag ctaaatcagt ataagttatt
    45001 actaaatagc aaggtatata atacatcata tgtggtagga gtttctacac ttccagaggg
    45061 aagaggagct ggatatatga acaaagtaat gaaatttact ttaaacgaat tgtataaaaa
    45121 agggcaatta gtttctatat tgatgcctat tgactataga ctttatagaa gatttggata
    45181 tgagcattgt tacgaccaga ttgaatatac tattaacaca gatgatttaa aaaattttaa
    45241 gtcaagtgga aaaatgataa agtctaattt atcacaaatt gatgatttga tacaaataga
    45301 tagaactttt ttaaatgagg ttaatggtaa tgtgttaaaa gatgaacatt attatgaaaa
    45361 cttatttaaa gagattcaaa gtgaagatgg atttttatac attcatgaag gaaatgaaaa
    45421 agatggatat atagtttatt ttcttcagga agataaaatg tttgtcagag agttatttta
    45481 taaaaatata gatgccctta aatcaatgct taaatttata tataatcaca atactcaatg
    45541 taagatagtt actatatcta ctcctacaat agataagata aggtttatat tagacaaccc
    45601 taaagatagt gatataaaaa taaaaccttt tatgatggga agagttataa atgtaaagaa
    45661 gtttattgaa gatatagata ttgagaagga tattaatagc tcatttaatt tattaataga
    45721 agacaagttt atagatgaaa ataatggtct atttaaaatt tctatacaga ataagaaggt
    45781 atctgtagag cagttagata aaaaaggtgc agaaaagcct caagaagatt ttgatattaa
    45841 attagatata aataccttaa cacagttatc attttcttat atagatgtaa atgaagctat
    45901 tttcttaaat gatataaaag atgtttcaga agaaacacta gaaacactta attgtatttt
//
LOCUS       DAJMZY010000022        42903 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.022, whole genome shotgun sequence.
ACCESSION   DAJMZY010000022 DAJMZY010000000
VERSION     DAJMZY010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 42903)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42903)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42903
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.022"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            <1..298
                     /locus_tag="OE968_001185"
     CDS             <1..298
                     /locus_tag="OE968_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HCP7218474.1"
                     /translation="EKGTPVIAIATQEKLFEKMVSNMEEVRARGAYVVAIAQSHNKDV
                     EKAADKIIYIPNSDDILSPILAVVPMQLLAYHVSVLRGCDVDKPRNLAKSVTVE"
     gene            749..2044
                     /locus_tag="OE968_001186"
     CDS             749..2044
                     /locus_tag="OE968_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiosulfate sulfurtransferase"
                     /protein_id="HCP7218475.1"
                     /translation="MTNDFKKEKKEDYFVNLKAISTEVLQEKVQDNAWVIVDTRLNDA
                     YNGWKLDGVKRGGHIKGAVDFSANWLSVYSDRKDEVLEQALKTKRIDLDKNIVLYDAN
                     GKDALVVADYLSKKGYKYLYKYDIKQWADNENLPMERYKNYQMIVPAFIIKDILDGKI
                     PETFEDSKNIKMIEASWGEESYTKGHIPTSVHVNTDIIEPPPTWMLDNDDNLIKFALD
                     YGLTKDDTVIVSSSTPMASYRLAVILRYIGVKDVRVLNGGTNSWLSAGYELEFTSNPK
                     HSCTNFGADIPVNSQLVVTTSELRQKLKEKNKFILVDNRTWDEHIGKVSGYTYYDKKG
                     RIPGALYGHSGSDSVSLEEYRNIDNTMRNKYEILEMWDKENIDVNRQLIFMCGSGWRA
                     AEVLTYANVIGVENTSLYSDGWMGWSLDNSNLIEVGEHK"
     gene            2494..3231
                     /locus_tag="OE968_001187"
     CDS             2494..3231
                     /locus_tag="OE968_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YwmB family TATA-box binding protein"
                     /protein_id="HCP7218476.1"
                     /translation="MKRVKLAISFFILMIIGMTISYADTSINTKYNRLSKALEISEAN
                     FKFYNVKINSVINHNLSNKEFHNIFIEIINNLKLDKKGINWNQKGSGDKIQLCATIKG
                     SDKEISIKGINKNNKESYIVVDILDNKVYKHKEVIYSNVENVLNKYSSQVDVSACIVG
                     EYTKRLQNNKYDDILQKILYNMSAKQIDEVKDVNFLSITAYSKVLNDYELEYLGEKIN
                     LNIGIKYNEDDGRTLIYIATPIIKLDY"
     gene            3252..4505
                     /gene="murA"
                     /locus_tag="OE968_001188"
     CDS             3252..4505
                     /gene="murA"
                     /locus_tag="OE968_001188"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HCP7218477.1"
                     /translation="MAKIIVKKSNPLKGSVKIDGAKNAVLPIIAATLLANGKSTLNGV
                     PNLRDVHVISDLLRHVGAEVEYKENTLTVDASNIKTCEAPYELVRKMRASFLVMGPLL
                     ARFNSTKISMPGGCAIGTRPIDLHLKGFKALGAKIEMDHGFVEAATEKLVGNKLYLDF
                     PSVGATENIMMAASLAEGTTIIENAAEEPEIVDLANFLNEMGADVKGAGTNTIKIKGV
                     KELKGAEHNVIPDRIEAATYMVAAAMTKGDITVENVLMEHLKPVVAKLREAGCEITEM
                     DNSVRVVGPKVLKPIDIKTLPHPGFPTDVQAQFMAMLTVANGTGVVIETVFENRFMHV
                     AEFNRMGANIKIDGRSAVVNGVDELHGAAVNATDLRAGAALILCGLIAEGETQIGEIY
                     HIQRGYVDIDKKITALGGQIEIVED"
     gene            4592..5656
                     /gene="spoIID"
                     /locus_tag="OE968_001189"
     CDS             4592..5656
                     /gene="spoIID"
                     /locus_tag="OE968_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein D"
                     /protein_id="HCP7218478.1"
                     /translation="MKNPLVVLLGFVTCSVLVPSLITLVSYKNVELTEKAESPVSINK
                     TIKKSDIEDKGNKEEKNTVNYETVNKKAPIINVYNHITGKTEKMDMENYLCGVLAGEM
                     SSEFDIEALKAQSVAARTYVVYKQEHGKSSKHKNAVVCTDYKHCQEYKSYDTLKKLNG
                     EEWIKNKYSKIQEAVRGTKGQIITYNDKAILPLYFSTSSGKTENSEEVFSAKYPYLKS
                     VESPYDKYSPKFASTLKISNTDFVKSLRRAYSTIVIDVNNLSKQVSITKRSDAGTVEK
                     IKLGNKELTGKDIRTVFKLNSANFDIKFGEGYIDFVVKGYGHGVGMSQWGAEGMAEEG
                     YKYYDILSHYYTDTKIKDIY"
     gene            5722..6390
                     /locus_tag="OE968_001190"
     CDS             5722..6390
                     /locus_tag="OE968_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M23 family metallopeptidase"
                     /protein_id="HCP7218479.1"
                     /translation="MKKKLLEKDGFYLSLFVCVCLLAVGGVWFTNNNVDKLASNKGIM
                     ENANKDSEEEIHLIEKDKKDAIPTATDSKQNLEKAKSKEENKSSTTKLNYIGDKVIRG
                     YSEKEPSYSKTLDVWETHKGVDISCTKGKEVKSLLNGIVVDVFNDEEYGQSVKIKSDN
                     NIVVVYSNLDKNVSVKKEQKVTEGQSLGTVGSTSQIESEEGIHVHLEAYSGEKSIDPM
                     SLIK"
     gene            6488..6748
                     /gene="spoIIID"
                     /locus_tag="OE968_001191"
     CDS             6488..6748
                     /gene="spoIIID"
                     /locus_tag="OE968_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation transcriptional regulator SpoIIID"
                     /protein_id="HCP7218480.1"
                     /translation="MRSHIEERAIVVAKYILEKNTTVRQTAKTFGVSKSTIHKDVTER
                     LKEINPSLAKEVKNVLDKNKSERHIRGGLATKLKYEKEHKKM"
     gene            6945..7964
                     /locus_tag="OE968_001192"
     CDS             6945..7964
                     /locus_tag="OE968_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein"
                     /protein_id="HCP7218481.1"
                     /translation="MAGADIGIDLGTANVLVYVSGKGIVLEEPSVVAIDNRTDSVLAV
                     GEEAKKMIGRTPGNIVAIRPLRDGVISDYDVTEKMLKSFIDKIVDKKGFGRFFMPRIM
                     VCVPTGVTEVEKRAVEDATRQAGAREVYIIEEPIAAAIGAGVDISQPNGNMIIDIGGG
                     TVDIAVISLGGAVVSESIKVGGDRFDDAIVKYMKKQHNLLIGERTAEKIKFEIGSAFK
                     REEEKYMKITGRNLITGLPSSITINSTEMLEALRECVEQIVVATHAVLEKTPPELAAD
                     IGDVGIIMTGGGSLLYGLDKIIEQRTGITVTIADEPLSCVAKGTGIALGSIDLLETGG
                     SFKRK"
     gene            7980..8408
                     /gene="fabZ"
                     /locus_tag="OE968_001193"
     CDS             7980..8408
                     /gene="fabZ"
                     /locus_tag="OE968_001193"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HCP7218482.1"
                     /translation="MLNIDEIKKLIPHRYPFLLVDKITELEVGKRAVGIKNVTVNEPF
                     FQGHFPEYPLMPGVLIVEALAQVCGVAMMSVEENKGKLGVFAGIDKVRIKREVRPGDT
                     LTMEVEMTTLRRNIAKADAKAYVGEELVCKGELMFALVEK"
     gene            complement(8519..9028)
                     /gene="yyaC"
                     /locus_tag="OE968_001194"
     CDS             complement(8519..9028)
                     /gene="yyaC"
                     /locus_tag="OE968_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore protease YyaC"
                     /protein_id="HCP7218483.1"
                     /translation="MYLAKVNYSDDDVIQMLSSVLKTIINENTIVVCIGTDRAIGDTL
                     GPLVGTILKNSNFKYPVYGTLDNPIHALNIYESLDTIKNTHIQGNFLAIDACLGSQSN
                     IGNIQIREGPILPGKGVGKKLPQIGNYSIVGIVDKIDENNKLSFNNIRLSFILDLAET
                     IALALLVST"
     regulatory      9217..9320
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            9456..10649
                     /locus_tag="OE968_001195"
     CDS             9456..10649
                     /locus_tag="OE968_001195"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HCP7218484.1"
                     /translation="MARHLFTSESVTEGHPDKICDQISDSILDALLEKDPQSRVACET
                     TVTTGLVLVAGEISTSAYVDIPKLVRETVREIGYTRAKYGFDCDTCAVITSIDEQSGD
                     IAMGVDEGLESKTGEEIEEEIEKVGAGDQGIMFGFACNETPELMPLPISLAHKLSRRL
                     TEVRKTGLVDYLRPDGKTQVTVEYEGSKAVRVHTVLISAQHCETVSNDKIREDLINHV
                     IKEVIPAELLDEDTKIYINPTGRFVIGGPQGDTGLTGRKIIIDTYGGYSRHGGGAFSG
                     KDPTKVDRSAAYAARYVAKNIVAAGLADKCEIELAYAIGIARPLSIFIDTFGTGKVSE
                     EKLVELVNKHFDLRPGAIIRDLDLRKPLYKKVAAYGHFGRTDIDLPWERTDKVEQLRK
                     DALGE"
     gene            10964..12061
                     /locus_tag="OE968_001196"
     CDS             10964..12061
                     /locus_tag="OE968_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218485.1"
                     /translation="MSGKVNIKTVISFAGAYVATVIGSGFATGQEILQFFTFYGYAGI
                     IGGIISMVLFSWFGAEVIDKGRELKLKEPIKIYQVYCGKYLGTFFEWFGPLFLFGTLV
                     IMIAGAGATLSEYYGLNPYVGRIGMTIVSLITVSLGLTRLSKILGNIGPIIIIFTLLV
                     GAISLFSNIDALSNAGNMVDSLNIKTATSNGYFSGVLYTCYNVIIVITFLTGMGASAV
                     NKKDAVWGGIVGGVALMAAAIMMNLALLSDIGNIYTKEIPALYLADKISPIIGILFSV
                     VLLLGIYTTAVPLLWSVTNRFVEDDHPKFKIITIVVSILACIGGLLPFDKLVGTLYPY
                     TGYMGILILLCMLYRRITKTEGYKENKSEIS"
     gene            12325..14544
                     /locus_tag="OE968_001197"
     CDS             12325..14544
                     /locus_tag="OE968_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HCP7218486.1"
                     /translation="MEKLEGMISEIVFKNEDNGYTIAHLVNENDEIVVVGCMPTLAIG
                     ESIEVEGKWVNHKIYGTQFEVNSFMPVTPSSLEGIYVYLSSGMIHGIGEKMAKRIIDK
                     FGVDTLEVIQNSPEKLQEVEGIGSKKVKQIVKSYEEDRELRNIIIQLSPFGITPNYCL
                     KIYKKYKSSAIEVINKNPYQLAEDIRGIGFKVADSIANKIGIDKNSKDRICQGILYTL
                     NKSLSNGHTYLPEHVLIQDSEKLLELNGEIIKECVMMLVYNQKIHVEKVNNENLIYLM
                     PYYLAENGVCSQIVKLSQYEFEDLKIDIDNEINVLEEDKKIKLAEKQILAVKESVNSG
                     VLIITGGPGTGKTTTINAIIDIFENNGKSVTLAAPTGRAAKRMSETSNKEAKTIHRLL
                     EMGFSTDDDLTFFKDEEDPINSDVIIVDEVSMVDIILMYNLLRAIKLGTRVILVGDSD
                     QLPSVGAGNVLKDMINSNIINVVKLNEIFRQAQESMIIVNAHKINNGEPLYLNTKGKD
                     FFFIRKSTNEEILNEIIGLVNERLPKFYKVDKLKDIQVLSSMRKGELGVTNLNIELQK
                     YLNKKEKFKVEESFSKRLFRVGDKVMQVKNNYTKKWETEDQKESGEGIYNGDIGYVYH
                     IDKDKKTIYILFDQTKIVSYLYDELDEIDHSFCTTIHKSQGSEFPVVVLPIAWAPPML
                     LSRNLLYTAVTRAKKLVVLVGDVKYLEYMIKNNRVNQRYSNLGYKLNKFKQEGLLIE"
     gene            14547..15329
                     /locus_tag="OE968_001198"
     CDS             14547..15329
                     /locus_tag="OE968_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HCP7218487.1"
                     /translation="MKICNDNFIKNFKNMINKCLDFIYPENISCIICDKSIKKTNTYS
                     ICKSCFKEMNFIQDGCMKCGKPIIRHSIEKEFIEECSYCFNKDFYFDKSISCIEYNDV
                     TKKIVLGLKYNQKTFMAKYIAQIMKEKLYLENIKFDYILFVPLHKKRLNKRGFNQAQK
                     IAFNLSKIVNIPLLDCISRKKYTRMLYKLNKKERKEELKNVFVVKDNVKLINNKNILL
                     IDDIFTTGLTTNEISKLLKLSGANKVFVLTLLTKANDNYIME"
     gene            15661..17574
                     /locus_tag="OE968_001199"
     CDS             15661..17574
                     /locus_tag="OE968_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HCP7218488.1"
                     /translation="MICLNKRQENLLTTLLLKEEFINVNKIANDFECSERTIRNDCKY
                     IDEWLSTFCNAYIKRKPNIGIKFSGDGTDKILVNQKLRGEVKRVNSELHKQVEILNLL
                     LCNNKKVTLNDLSNKLYINKNIVREEISKLSVALNNYNLNVSTKKGSGIYIGGDEKDI
                     RIMLVSFLFKYIDKYRLNIDEIEYFHIVDIIIVKNIMFTIEEDMDIRLTDISFKQLML
                     FLLINIIRIRLGNSLKVSNTKKELKLKMLILDIEDELKSNLSIVLNYEEKLFIESLIL
                     GMNKQINSSNIKKSLYLNEELASYTKKIINLVSEESGINFNNDILLYEQLICHLNVTM
                     HQMKSNVYLENPLLDNIKTKFCFLFTVISSSIEIELKGKQITEDEIGYLTLHFQTSLE
                     RKYSKRESNKKASIVCPFSFGVSMLLKVKIEKRFDNIKIIETLREEDLKRDNFNKTID
                     FIIAFQEYENIQKPIFITTPLFTDEDENKLKEFTNKIKEKDTSYKLMNRLMMSDYLIR
                     ELEHDDIYEAITYLTNLLIEKHYAEKEYLQSIITREKSYPTNVGKGILFPHGDMKYIK
                     QSVLCFARLKTPIRIRNGKDIKIILLLAYKKDDDRKVFRELFKEISNLTEDENMLDIL
                     SKCDIEKVKDILI"
     gene            17715..18023
                     /locus_tag="OE968_001200"
     CDS             17715..18023
                     /locus_tag="OE968_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HCP7218489.1"
                     /translation="MEEIVLKIIIHAGNAKSMLYEALDYAKENDFKKADELIENANEE
                     ILKAHKVQTELIQKEAGGDKSDISILLIHSQDHLMTCMSERNLIKEMIMLRKEIQKLK
                     "
     gene            18047..18373
                     /locus_tag="OE968_001201"
     CDS             18047..18373
                     /locus_tag="OE968_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCP7218490.1"
                     /translation="MKRKVYLFCSFGMSTSLLADKMQKVADEHNLPIEVEAFPIAEID
                     KIVEEKNPDCILLGPQVKYMLKELKPKFEAQGKLIDIINEVDYGTMNGEKVLKLAIKL
                     IKSKQA"
     gene            18412..19746
                     /gene="celB"
                     /locus_tag="OE968_001202"
     CDS             18412..19746
                     /gene="celB"
                     /locus_tag="OE968_001202"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HCP7218491.1"
                     /translation="MNRLERILMPLAEKIGKNKLLIAIRDGFLISSPLLIIGSLFLLV
                     ANFPIKGWNEFVGQIFGSDWAVKLQQPTVATFEVMTLLAVLGIGYSYAKQIDVDPIAS
                     AAVAIVAFFIITPFVIPYTPEGTESVYMVTGIPLGWMGSKGMFVGMITAITSVKLFAA
                     VVKKGWTLKMPDGVPPTVSKSFAALIPSAIVMVVFFLVKIAFEATPYGSIHEFIFKFL
                     QMPLLKLGNSLGAMAIAYIFLHLFWFFGINGSSVVGAVYNPILKILSAENLAAFQAGS
                     KIPNIITGQFQDMFATFGGAGSTLSLVIAMLLICKSKRIKSMGKLSILPGIFGINEPL
                     IFGLPIMLNPILLIPFAIVPTINIIIAYFCMSAGLVPLTNGVQLPWTTPIIFSGFLTT
                     GWQGAVLQVVLLILGIFMYIPFIKMLDKQYLREENATVEEEDDDISFDDLVL"
     gene            19757..20275
                     /locus_tag="OE968_001203"
     CDS             19757..20275
                     /locus_tag="OE968_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine/betaine/sarcosine/D-proline family
                     reductase selenoprotein B"
                     /protein_id="HCP7218492.1"
                     /translation="MKKIVMILDQIQAGAGGKEKSNIPPAGKSSPLGPGIMMEQFLNE
                     SKVIATLFCGDEFFVNNEEEVTSKMIAMVKKLNPDVVICGPSFNYENFSKMSAILSKN
                     INDKTDIPAFAAMSEENIDVINEYKNDICIVKTPKKGGIGLNDSLNNICKLAKAIANK
                     EDITLMKEEFCY"
     gene            20371..21330
                     /locus_tag="OE968_001204"
     CDS             20371..21330
                     /locus_tag="OE968_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase"
                     /protein_id="HCP7218493.1"
                     /translation="MWGMIATWRMALEGITEASEHLEKGMEAGDAVELAVRRVEDYPF
                     YKSVGYGGLPNENCEVELDAAFMDGNTLDIGAVAGIRDYSNPVSIARKLSYEKVNNFL
                     VGIGAEDYAHKNGFERKNMLTDRAKLHYKKRKKETLDKGLSPYAGHDTVGMISLDKTG
                     KMCAATSTSGLFMKKRGRIGDSALSGSGFYVDSSIGGATATGLGEDLMKGCISYEIVR
                     LMKEGKHPQEACDIAVNELDKQLIKRRGKAGDLSLVAMNNKGEWGVATNIADFTFSVV
                     TKEESPTVYISNRVDGKTIHKVISNEWMEAYEARIKAPIEVSE"
     gene            21379..22431
                     /locus_tag="OE968_001205"
     CDS             21379..22431
                     /locus_tag="OE968_001205"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sapep family Mn(2+)-dependent dipeptidase"
                     /protein_id="HCP7218494.1"
                     /translation="MNIISNKIDELKEDLLSDIIDIVKIPSVKGESENGFPFGEKVGE
                     ALNKALEISEKLGFKVRNLDNYIGYAEHGDSDDYVCVIGHVDVVHEGDGWKHQPYKGE
                     ETNGRIYGRGVLDNKGPIMSALYGLYAIKELNLKLDKRVRIIFGTNEESGFEDIPYYL
                     EKEKAPIMGFTPDCKYPVVYGEKGMAKIRIKSKINYEEDVYLGFIENMSENVLVTYKE
                     LNIENSDTILDIKVKYDFSYKLKDVLDEIKASFPNSIDIEVISNFNPVYFDKESNLVK
                     KLQLAYERVTSLDGTPVTTNGGTYAKVMPNIVPFGPSFPGQKGIAHNPDEYMDIEDII
                     LNAKIFANAIYELAKE"
     gene            22434..23108
                     /locus_tag="OE968_001206"
     CDS             22434..23108
                     /locus_tag="OE968_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HCP7218495.1"
                     /translation="MLEIIGMSVEDAKIIEDCGADRIELVSALTEGGLTPSFGLIESV
                     VNSVKIPVNVMIRHHAKSFVYSKEDISIMQKDISVVKEIGANGVVFGVLDKNNSIDEK
                     NLNVLLKCCDNLDVTFHRAIDESNTIDSVKILKDYDKITNILTSGGKGSIVDNIQMIK
                     NMMLSSNHIKILLGGGLNFNNIEKIKELTKASNFHFGTAIRINNSPFEDIDRQKLKQL
                     VNIISR"
     gene            23661..24212
                     /gene="raiA"
                     /locus_tag="OE968_001207"
     CDS             23661..24212
                     /gene="raiA"
                     /locus_tag="OE968_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HCP7218496.1"
                     /translation="MNIIISGKQIELTDAIKNKIETKLSKLDNYIHPDTDVKVTVSAR
                     KARQKIEVTIATVNGPIIRAEDMQENLYTAIDVVYDKLSKQLKKYKKRLQDKHKDNKS
                     IRFQDAEINLADEQEDYGDENQELVIQRRKKFSVKPMSEEEAVLQMELIGHDFYMFKN
                     IDSDEIAVVYKRNNGGYGIIEHE"
     gene            24344..27019
                     /gene="secA"
                     /locus_tag="OE968_001208"
     CDS             24344..27019
                     /gene="secA"
                     /locus_tag="OE968_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HCP7218497.1"
                     /translation="MSFMDNLFNMADKKELKKFNKTVDIIDSLEPKFESMADSELKNM
                     TNIFKERLANGESIDDILPEAFAVVREVSKRVLGLRHYRVQMIGGIVLHQGRIAEMKT
                     GEGKTLVATAPVYLNALTGKGVHVVTVNDYLAKRDRDQMAKIYEFLGMSVGVIIHGQN
                     PKVRKEQYDCDITYGTNNEYGFDYLKDNMVIHKEQRVQRGLNYAIVDEVDSILIDEAR
                     TPLIISGPGDKSTHLYSDANTFVLTLKPDDYELEEKDKAVSLTASGIQKAEVYFNVDN
                     ITDISHTELYHHINQALRAHVIMKKDVDYVAKDGEIVIVDEFTGRLMFGRRYSEGLHQ
                     AIEAKEGLKIQRESKTLATVTFQNYFRMYKKLSGMTGTAKTEEEEFKAIYKMDVFQVP
                     TNKLMIREDLPDCVYKSEIGKFNAVAQEIIERHKVNQPILVGTVSIEKSELLSQILKK
                     KGIKHEVLNAKHHDKEAEIIAQAGRLGAVTIATNMAGRGTDIVLGGNPDFLTKREMRR
                     NGFKEEIVNRVDTPIEGIPVKGNEILFEAREEYEKLFEKFKQQTQEEQKQVVEAGGLA
                     IIGTERHESRRIDNQLRGRAGRQGDPGSSRFYIGLDDDLMRLFGSDRISGIVDKIGLE
                     EDMPIEHRILSKSIEGAQKKVEGKNFGIRKHVLQYDDVMNKQREIIYAERKRVLEGED
                     LQEQIQSMTHSIIEEAVTLYTQDKGFDEEGFKEHMYNLFLPKGSIEIPEIEKLNPVEI
                     TEKVYEIAMKIYTSKEEQVGYERMREVERVILLQAVDNHWIDHIDAMDQLRQGIGLRA
                     VGQQDPVIAYKMEGFDMFDEMNKHIKEDTVRYLFNITIETPVERKAVVDVENLSSPSD
                     GTLPTSKTVKKDEKVGRNDLCPCGSGKKYKNCCGR"
     gene            27034..28141
                     /gene="prfB"
                     /locus_tag="OE968_001209"
     CDS             join(27034..27108,27110..28141)
                     /gene="prfB"
                     /locus_tag="OE968_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_153309863.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HCP7218498.1"
                     /translation="MLKLQEYRHSMEQMASNLEELRVSLDIASLMKNIQINEEKMNKQ
                     DFWNDNEVAQRVLQENKSLKETLEEYESLKSLLEDIEVLIEIGLEEDDDSVERDIEKS
                     IESMEEKLSEMKIKTLLNGEYDKNNAILSINAGTGGLDAQDWAQMLLRMYIRWSESKG
                     YKVKLLDIISDPEAGIKTATILVEGTNAYGYLKSEKGVHRLVRISPFDPSGKRHTSFA
                     SIDVTPELDENIEVEINPSDLKIDTYRASGAGGQHVNTTDSAVRITHIPTGVVVQCQN
                     ERSQHLNKDRAMRLLMAKLIELKELEQKEKIEDIQGKYSQITWGSQIRSYVFQPYKLV
                     KDHRTNAEFGNVDSVMNGNIDLFINEYLKMNKIV"
     gene            28285..30426
                     /locus_tag="OE968_001210"
     CDS             28285..30426
                     /locus_tag="OE968_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011010799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HCP7218499.1"
                     /translation="MDINQILKKEFNLRDEQINNTLKLIDEGNTIPFIARYRKEMTGE
                     MSDVTLREFYEKLMYLRNLQSRKDDVVRLIDEQGKLTDEITQNIEKAKTLQEVEDIYA
                     PYKQKKRTRATIAKEKGLEKLALSILENNLDNIEIEAKNYLDEEKEVLSIEDALKGAR
                     DIIAELVSDDAKIRKYIRELALREGMIVSKSATDEKSVYDMYYDYSEAVKSMPPHRVL
                     AINRGEKENFLKVKLEINNDKVLNYIINEYVNDKNFKNKEEIVSSIEDSYKRLIFPSI
                     EREIRNHLTEIAQERAISVFGKNVKSLLLQPPVKDKVVMGFDPAFRTGCKIAVVDKNG
                     KLLDYTTVYPTDPQNDVEGAKKVLKGLIEKYDIDIISIGNGTASRESETFVSEMIKEI
                     DNEVQYVIVSEAGASVYSASELANEEHPDINVSIRGAISIARRLQDPLAELVKIDPKS
                     IGVGQYQHDLNKKRLEEVLDGVVEDSVNSVGVDLNTASYSLLEHVAGISKTIAKNIIA
                     YREENGDFTSRAQLKKVKRLGPQAFTQCAGFMRILEGKNPLDNTGVHPESYDICKKMI
                     EIIGYSLDDVKNKNICEIDEKIKEIGLRELSEKLEVGQVTLKDIITEIKKPGRDPREE
                     GIKPILRTDVLKIEDIQEGMTLKGTIRNVVDFGAFVDIGIKNDGLVHKSEMSNSFVKD
                     PMSIVTVGDIVDVKVIGIDLNKKRVALSMKK"
     gene            30574..31740
                     /locus_tag="OE968_001211"
     CDS             30574..31740
                     /locus_tag="OE968_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HCP7218500.1"
                     /translation="MIFIKNGKINTITNGIIHGDILIDEGKIIEIGEDLIAPLDVEVI
                     DASNKLVFPGFIDAHTHLGLWEDGIGFEGADGNEETDPITPQLNPIDGINPMDRTFKE
                     AFEGGITSVCTTPGSANVMGGQCIAIKTCGKRIDKMVIKNPVASKIAFGENPKSCYGQ
                     DDKSPQTRMAIAALLRENLKKAEEYLEDIDMYESHDDEDCEKPEYDIKMESLIPVLRR
                     EIPFKAHAHRADDMFTAIRIAKEFNLKLTLDHCTEGHLIVDELVEEGFPVIVGPSLSE
                     RSKFELRNLTFNTAGILSNAGLDVCIMTDHPVIPVQYLPICAGIAVKHGMKEEKAIES
                     ITINPAKTLGIEDRVGSIEVGKDADLVIWDNSPLEIQSNVLYTIINGKVVYEKK"
     regulatory      31800..31917
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            32041..32646
                     /locus_tag="OE968_001212"
     CDS             32041..32646
                     /locus_tag="OE968_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HCP7218501.1"
                     /translation="MQNTAKRGNMISTRTLVVMSILSAISYLLMFIQAPIPGIFPDFL
                     KIDLSDIPAIFGGMSLGPFVGFGIVVVKNVLQAITATTTGGIGEFANILIGGSYVMIL
                     CYSYKRSGDLKGVLIGFVLGTISMTIIGSLVNYFVMLPLYGQLMGLDAIIGLGSAINP
                     QVHDLFTFVIWMIAPFNVLKAVILSLVTLPLYKKMGNVIKK"
     gene            32975..34015
                     /locus_tag="OE968_001213"
     CDS             32975..34015
                     /locus_tag="OE968_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4116 domain-containing protein"
                     /protein_id="HCP7218502.1"
                     /translation="MNLSKKIKKLFLDDKGYYFNSNWKDIHIGIYNTKLGDSLKYITN
                     EYIENLERVKYDYRELKNIENQTDGMCILAIRQNYKALEYVKNQTEELCLEAIKYNYK
                     ALEYVKEQTEYICLEAIKKDCNALKYVRNKTERLIIKVIRHSSNIDVVSILKALETQT
                     RRICLEAIKKDGRCLAYVREQSEELCIEAIKQNYKALKYVENQTEKMCIESVRQNGMA
                     LQYVNKQTDKICIEAVKQDGRSLQFVNNKTEEICINAIRYLNKKYNIKDVLSYIDKYT
                     EDICIEIVRQNGKMLMYIKNQTEKMCIEAVKENYKSLKYVKEQSERICKEALKQNHKA
                     KEYVKIAIDDCI"
     gene            34154..34606
                     /gene="tsaE"
                     /locus_tag="OE968_001214"
     CDS             34154..34606
                     /gene="tsaE"
                     /locus_tag="OE968_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HCP7218503.1"
                     /translation="MAKIYLENENKTREIGYKLGKLLKEGSVICLVGDLGAGKTTMTQ
                     SLADSLGIEDYITSPTFTIINEYEGKIPLYHFDVYRIGSSDEMYDIGYDEYVNSNGIC
                     IIEWANLIEDILPKEYLNIELRYKDDGREMILTPKGEFYKEIVEELIK"
     gene            34606..35322
                     /gene="tsaB"
                     /locus_tag="OE968_001215"
     CDS             34606..35322
                     /gene="tsaB"
                     /locus_tag="OE968_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HCP7218504.1"
                     /translation="MKILGMDTSSMAASVAVVEDDNLICEFTVNNKKTHSQKLMPMIE
                     NMLSMSDLSIKDMDLLAVCIGPGSFTGLRIGMATVKAMAHVNNIPIIAVNSLESLANN
                     INFCDRKICCILDAQKNQVYSAKYKFENGEMIELDGVDVVEFDALVDEIVSTNEEFII
                     VGEAVYKYKDKLENIKNIKIPSPANNVSNAGSLCSLALNKYNKNIDVHTCYTINPMYI
                     RKSQAEVQYDEKMKRLNNGR"
     gene            35312..35788
                     /gene="rimI"
                     /locus_tag="OE968_001216"
     CDS             35312..35788
                     /gene="rimI"
                     /locus_tag="OE968_001216"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HCP7218505.1"
                     /translation="MEDNTKLIVDDIKIEEMTTEDIDEVFEVEKNCFEDYWSKESFRK
                     ELSNEVARYIVAKLNGKIVGYVGIWLILDEGHINNVAVHSDYRGKKIGDKLIKGIVDL
                     CKDNNIASMTLEVRASNKIAQNLYRKYGFKMGGIRKEYYSDNKEDAIIMWNQLKEV"
     gene            35794..36810
                     /gene="tsaD"
                     /locus_tag="OE968_001217"
     CDS             35794..36810
                     /gene="tsaD"
                     /locus_tag="OE968_001217"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HCP7218506.1"
                     /translation="MSDIITLAIESSCDETAASVLKNGREVLSNIISTQIETHKKFGG
                     VVPEVASRKHVENIDIVVQEALDKANIGFNDIDHIAVTYGPGLVGALLVGLSYAKALA
                     YTLNIPLVGVNHIEGHLSANYIEHKDLKPPFITLIVSGGHTHLVEVKDYGKYEILGKT
                     RDDASGEAFDKISRAMNLGYPGGPIIDNLAKKGNKHAIEFPRAYLEEDSYDFSFSGLK
                     SSVLNYLNGKRMKNEEIVVEDVAASFQEAVVEVLSTKALKAVKEKGYNIITLSGGVAS
                     NSGLRAKITELAKDSGITVKYPPLILCTDNAAMIGCAGYYNFINGKTHDMSLNAVPNL
                     KINQ"
     gene            37107..39815
                     /gene="hpdB"
                     /locus_tag="OE968_001218"
     CDS             37107..39815
                     /gene="hpdB"
                     /locus_tag="OE968_001218"
                     /EC_number="4.1.1.83"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate decarboxylase large
                     subunit"
                     /protein_id="HCP7218507.1"
                     /translation="MSQSKEDKIRSILEAKNIKSNFQNKENLSEFNEKKASKRAEDLL
                     DVYYNTLSTADMEFPYWYNREYRKSDGDIPVVRRAKALKSAFSHMTPNIIPGEKIVMQ
                     KTRHYRGSFPMPWVSESFFVAQGEQMREEAKKLASNTADELTKFGSGGGNVTESFGNV
                     VSIAGKFGMRKEEVPVLVKMAKEWVGKSVEDLGFHYEKMMPDYDLKENLMSTLICMFD
                     SGYTLPQGREVINYFYPLNYGLDGIIEMAKECKKAVAGNASGDGLIGMDRLYFYEAVI
                     QVIEGLQTWILNYAKHAKYLESIETDLEAKKEYSDLVEILEHIAHKQPRTFREALQLT
                     YTIHIASVNEDAISGMSIGRFGQILYPWYEQDIEKGLITKEEVIELLELYRIKITCID
                     CFASAGVNGGVLSGNTFNTLSIGGLKEDGSTGANELEELLLEASMRCRTPQPSLTMLY
                     DEKLPEDFLMKAAECTKLGSGYPAWVNNSNGTTFMMKQFADEGMTVEEARAFALGGCL
                     ETSPGCWKQLTLNGKTYSIAGGAGQSAGSGVHFIANPKILELVLMNGKDHRMNIQVFE
                     PHNKPLDTYEEVIEVFKDYYKQAINVLERANNIELDIWRKFDTSIINSLLKPDCLDKG
                     QHIGNMGYRYNATLNVETCGTVTMVNSFAALKKLVYDDKAFTIEEMKDAILNNFGFKD
                     ALEVGNYSMADQVKVDKTGKYDAIYKACLDAPKYGNNDLYADNILKNYEVWLSKVCEE
                     AQSLYAKKMYPCQISVSTHGPQGAATLATADGRLSGTTYSDGSVSAYAGTDKNGVYAL
                     FESATIWDQAVVQNSQMNLKLHPTTIKGQQGTKKLLDLTRSYLRKGGFHIQYNVVDSE
                     TLKDAQKNPDNYRQLMVRVAGFTQYWCELGKPIQDEVIARTEYEGV"
     gene            39819..40076
                     /gene="hpdC"
                     /locus_tag="OE968_001219"
     CDS             39819..40076
                     /gene="hpdC"
                     /locus_tag="OE968_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate decarboxylase small
                     subunit"
                     /protein_id="HCP7218508.1"
                     /translation="MRKHSDCMNFCAVDATKGICRLSKQMINLDDAACPEIKVMPKCK
                     NCKNFVEANDEGIGKCVGLEKEDWVYSTLNAITCEGHVFNE"
     gene            40069..41019
                     /gene="hpdA"
                     /locus_tag="OE968_001220"
     CDS             40069..41019
                     /gene="hpdA"
                     /locus_tag="OE968_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate decarboxylase activase"
                     /protein_id="HCP7218509.1"
                     /translation="MSSQKQLEGMIFDVQSFSVHDGPGCRTTVFLNGCPLSCKWCANP
                     ESWTVRPHMMFSELSCQYENGCTVCHGKCKNGALSFNLDNKPVIDWNICKDCESFECV
                     NSCYYNAFKLCAKPYTVDELVQVIKRDSNNWRSNGGVTFSGGEPLLQHEFLHEVLLKC
                     HEVNIHTAIETSACVSNEVFNKIFNDIDFAFIDIKHMDREKHKEQTGVYNDLILENIS
                     NLANSDWNGRLVLRVPVISGFNDSDENISDIISFMHKNNLVEINLLPFHRLGESKWIQ
                     LGKEYEYSDKGDVDEGHLGELQDIFLDNGIACYVGHETAF"
     gene            41334..42296
                     /locus_tag="OE968_001221"
                     /pseudo
     CDS             41334..42296
                     /locus_tag="OE968_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112760.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
     gene            complement(42395..>42903)
                     /locus_tag="OE968_001222"
     CDS             complement(42395..>42903)
                     /locus_tag="OE968_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HCP7218510.1"
                     /translation="IVPTSFILILQGSQPNYSGIIKFIFTPITSLTTIYIFFSEEYAW
                     RGFLQNIFFNKFGKKLGVIILGICWSLWHLPLIFTLYTPETPILGLILRSIHIVGISI
                     FLGYLYIKTKNIWFCAIIHILNNSAFLITNSKESTITYHDILIVSMVVLIFYVPFLFT
                     KEYKNNLE"
BASE COUNT        17374 a         4479 c         8036 g        13014 t
ORIGIN      
        1 agaaaaagga actcctgtaa ttgccatagc tactcaagaa aagttatttg aaaaaatggt
       61 ttctaatatg gaagaagtaa gagcaagagg agcttatgta gtagcaatag ctcaaagcca
      121 taataaggat gttgagaaag ctgctgataa aataatctat ataccaaatt cagatgatat
      181 tttatcacca atattagcag ttgtaccaat gcaattactt gcttatcatg tctctgtact
      241 aagaggatgc gatgtagata agccaagaaa tctagctaaa tcagtaacag ttgaataaaa
      301 acagattaaa aattaaatag ataatattta ttgaaaagaa ctcatcctgt tatttgtatt
      361 ttataggatg agttttttaa ataaatatta aatttgtttt gtttttgcta taataaattt
      421 tataaaaaga ttgatattaa atcatctgta aaatgataaa tatatagacc ataccaggta
      481 tagggaacga taaatatagt tcatataaaa tatagtgagt acttaataaa catatagtca
      541 atatcagata aaaaaaataa tagcttatga gaaaaattaa aatacaaggt attagtaacc
      601 ttgtgataag ataaagtgag tagtttaaaa taagaatata aggaactatt tataaaagaa
      661 tataatgaag ctaataaagt ataagaaaat tactttattt tagtaaaata atttcaaata
      721 aaaatttttt aaattgggag tataaattat gacaaatgat tttaaaaaag aaaagaaaga
      781 agattatttt gttaatctta aggcaatatc tactgaagtt ttacaagaaa aagtgcaaga
      841 taacgcttgg gttatagttg atactcgctt aaatgatgct tataatggct ggaagttaga
      901 tggagtaaaa agaggtggac atataaaagg agcagtagat ttttctgcta attggttaag
      961 tgtatactca gatagaaaag atgaagtgct agaacaagca ttgaaaacta aaagaattga
     1021 tttagataaa aatatagtat tatatgatgc aaatggaaaa gatgctttgg ttgtagcaga
     1081 ttatttatct aaaaaaggat ataaatatct atataaatat gatattaaac aatgggcaga
     1141 caacgaaaat cttccaatgg aaagatataa aaattatcaa atgatagttc ctgcttttat
     1201 aataaaagat atattagatg gaaaaattcc tgagacattt gaagattcaa agaatataaa
     1261 aatgattgaa gcgagttggg gagaagaatc gtatacaaaa gggcatatac ctacaagtgt
     1321 tcatgtaaat accgatatta tagaacctcc tccaacatgg atgcttgata atgatgataa
     1381 cttaattaag tttgctttag actatggatt aacaaaggat gatactgtaa tagtttcaag
     1441 tagtacacct atggcatctt atagactagc tgttatattg agatatatag gagtaaaaga
     1501 tgtaagagtt ttgaatggtg gaacaaactc atggttatca gcaggatatg aattagaatt
     1561 tactagtaat ccaaaacatt catgtactaa ttttggagca gatataccag ttaactcaca
     1621 attagttgtt actacctctg aattaagaca aaaactaaaa gaaaaaaata agtttatact
     1681 agtagataac cgtacttggg atgaacatat aggaaaagta tctggatata catattatga
     1741 taaaaaaggg cgtataccag gagctttata tggacattca ggtagtgata gtgtttcact
     1801 agaagaatat cgtaatattg ataatacaat gagaaataaa tatgagattt tagaaatgtg
     1861 ggacaaggaa aatatagatg tgaatagaca gcttatattt atgtgtggaa gtggatggcg
     1921 tgctgctgaa gtattaacat acgcaaatgt cataggagtg gaaaatacct ccctttatag
     1981 tgatggatgg atgggctgga gtcttgataa ttcaaattta attgaagtgg gagaacacaa
     2041 ataaagtttt tgaaagtacg atagagttgt ttaaaacaaa ggtgtttttg atttattggg
     2101 aagagtgtgt aaattgtgtt ttgggaagtg tacttaggta tgttcatttg gagctatgga
     2161 aattgataaa aaagtattat ctgtttattt tgctggtaaa atgtgaatag attatagatt
     2221 atagattata gattatagat ttaagtatag actaagtaat ttatattaca gaagagaata
     2281 tataagaact agtgcaagat gtatttgata catataaaaa attggcaaat ccagaataag
     2341 gatagagaaa attgagattg aagagtttga aagagactta ttagatgaaa aatacaaaga
     2401 tgtataaaaa tacatattga gaaagtatat ctctcttaaa tttgttaata attctattat
     2461 acagaaaaac atatttaagg gggatttttt actatgaaaa gagtaaaatt agctataagc
     2521 ttttttatat taatgattat agggatgaca atatcttatg cagatacaag tataaatact
     2581 aaatacaata gattaagtaa agctcttgaa atttcagaag caaattttaa attttataat
     2641 gttaaaatta attctgttat aaatcataat ttatcaaata aagaatttca taatattttt
     2701 atagaaataa ttaacaatct aaagttggat aaaaaaggaa taaattggaa tcaaaaaggg
     2761 tctggcgata aaatacaatt atgtgctact ataaaaggta gcgataaaga aatttctata
     2821 aaaggaataa ataaaaataa caaagaaagt tacatagtag ttgacatatt ggataacaaa
     2881 gtatataaac ataaagaggt tatttatagt aacgtagaaa atgtgttaaa taaatattca
     2941 tctcaagtag atgtgtctgc ttgtattgtt ggagaataca caaaaaggtt acaaaacaac
     3001 aaatatgatg atattttaca aaaaatatta tataatatga gtgctaagca aatagatgaa
     3061 gtgaaagacg taaacttttt atctataaca gcatatagta aagtattaaa tgattatgaa
     3121 ttagaatatt taggggaaaa aattaattta aatataggaa ttaaatataa tgaggacgac
     3181 ggaagaacac tcatatatat tgccacacca attataaaat tagattatta attatgagga
     3241 gatcaaaaaa tatggctaag ataatagtaa aaaagagtaa tccacttaaa ggtagtgtta
     3301 aaatagatgg tgcaaaaaat gcagttttac caataatagc agcgacttta ttagcaaacg
     3361 ggaaatcaac attaaatgga gtaccaaatt taagagatgt tcatgttata tcagatttat
     3421 taagacatgt aggggcagaa gttgaatata aagaaaatac acttactgtt gatgcaagta
     3481 atataaaaac ttgtgaagct ccatatgagc ttgtaagaaa gatgagagct tcttttttgg
     3541 ttatggggcc attgcttgct agatttaata gtacgaaaat ttctatgcca ggaggatgcg
     3601 ctataggaac aagacctata gatttacatt taaaaggatt taaagcctta ggtgcaaaga
     3661 tagaaatgga ccatggtttt gttgaagcag caacagaaaa attagtagga aataaattat
     3721 atttagattt cccatctgtt ggagcaactg aaaacataat gatggcagct tctttagcag
     3781 aagggactac aataatagag aatgcagcag aagagccaga aatagtagat ttagcaaact
     3841 tcttgaacga aatgggagca gatgttaaag gtgcaggtac taatactata aaaataaaag
     3901 gtgttaaaga gttaaaagga gcagaacata atgtaattcc agacagaata gaagcagcaa
     3961 cttatatggt tgcagcagct atgacaaaag gtgatataac tgttgaaaat gttttaatgg
     4021 agcatttaaa accagttgta gctaaattaa gagaagctgg ttgtgaaata acagaaatgg
     4081 acaattctgt aagagttgta ggtccaaaag tattaaaacc aatagatata aaaactttac
     4141 cacatccagg atttcctaca gatgttcaag cacaatttat ggctatgctt actgtagcta
     4201 atggaactgg tgtagttata gaaactgttt ttgaaaacag atttatgcat gttgctgaat
     4261 ttaatagaat gggtgctaat ataaaaatag atggaagaag tgcggttgtt aatggtgtag
     4321 atgagctaca tggtgcagca gtaaacgcta ctgatttaag agcaggggca gcccttattt
     4381 tatgcggtct tatagcagaa ggagaaactc aaataggaga aatataccat atccaaagag
     4441 gctatgttga tatagataag aagataacag cattaggtgg tcaaatcgaa atagtagaag
     4501 attaataatt ggtttataga agaaagttat aaattaatag ggttgttcat atacttaaat
     4561 acaaggtttt aaaagctaag gaggagagta tatgaagaac ccattggttg ttttgttagg
     4621 atttgtgact tgctctgtgt tagttccatc acttataact ttagtttctt ataaaaatgt
     4681 agaattaact gaaaaagcag agagcccagt atctataaac aaaactatta aaaaaagtga
     4741 tattgaagac aaaggtaata aagaagaaaa aaatacagtg aactatgaaa ctgtaaataa
     4801 aaaagcacca attatcaatg tatataatca tataacaggg aaaaccgaaa agatggacat
     4861 ggagaactat ttatgtggag tactagctgg tgagatgtct tcagagtttg atatagaagc
     4921 cttaaaagct caatctgtag cagctagaac atatgtagta tataaacagg aacatggtaa
     4981 atctagtaaa cataaaaatg cagtagtatg tactgattat aaacattgtc aagaatataa
     5041 gagttatgat actcttaaaa aattaaatgg tgaagaatgg attaagaata aatattccaa
     5101 aatccaagaa gcagttagag gaactaaagg tcaaataata acttataacg ataaggcgat
     5161 acttcctctt tatttttcta catcttcagg aaaaacagaa aatagtgaag aagtattttc
     5221 tgcaaaatat ccttatttaa agtctgtgga aagtccttat gataagtatt cccctaaatt
     5281 tgcgtcaaca cttaaaataa gcaacacaga ttttgttaaa agtcttagaa gggcatatag
     5341 cactattgtg atagatgtga ataatttaag taaacaagtt tcaataacta aaagaagtga
     5401 tgccggaact gtagaaaaaa taaaattagg aaataaagaa ttgactggaa aagacattag
     5461 aactgttttt aaattgaact ctgcaaactt tgacataaaa tttggagaag gatacataga
     5521 tttcgtggta aaaggatatg gtcatggtgt tggtatgagc cagtggggag cagaaggaat
     5581 ggcagaagag ggctataaat attatgatat attatcacat tactatacag atacaaaaat
     5641 aaaagatata tactaataat tgtataaaat gccaaaaaca cgtcaataat ccaaatgtag
     5701 aaatatattt ggaggtgcaa aatgaagaaa aagctgttag aaaaagatgg tttttattta
     5761 tctttgtttg tatgtgtttg tttattagca gtaggtggag tttggtttac aaataataat
     5821 gtagataaat tggcttctaa taaaggaatt atggaaaatg ctaataaaga tagtgaagag
     5881 gaaatacatt taattgaaaa agacaagaaa gatgctatcc ctactgcaac ggattcaaaa
     5941 caaaacttag aaaaagctaa gtcaaaagag gaaaataaat cgagtacaac aaaattaaat
     6001 tacattggag ataaagtaat aagaggatat tcagaaaaag aacctagtta ttctaaaaca
     6061 cttgatgttt gggaaactca taaaggtgta gatattagtt gtactaaagg caaagaagta
     6121 aaatctctat taaacggaat agtagtagat gtatttaatg atgaagaata tgggcaatca
     6181 gtcaaaataa aaagtgacaa taacattgta gtagtatatt caaatctaga taaaaatgtt
     6241 agtgttaaga aagaacagaa ggtaacagaa ggacaatctc taggtactgt aggtagtact
     6301 tctcaaatag aaagtgaaga aggtatacat gttcatttag aggcgtatag tggagaaaaa
     6361 tctatagacc caatgagtct aattaagtaa aagtataaca agtttaatca tatttggtta
     6421 agcttgttat attttttggt gtttttacat atatatcatt aaagctatta tgtgaggggg
     6481 gtaatctttg agatctcata tagaggaaag ggccatagtg gtagcaaaat atatacttga
     6541 aaaaaacact acagtaagac aaaccgccaa gacatttgga gtaagtaaaa gtacaattca
     6601 taaggatgtt acagaaagat tgaaggaaat aaatccatcc cttgccaaag aagttaaaaa
     6661 tgtgctggac aaaaataaat cagagagaca tattagaggg ggattagcaa cgaaattaaa
     6721 atatgagaag gaacataaaa aaatgtaggt taaaaaccta ctttttttat ttaattaaat
     6781 tataaaaaga aatatattaa gtaattataa atagcaaaat aataatactc tcaaaagatt
     6841 tattttctct tgattaaagc gagatttttg tatatgcttt attataggag tattaaaata
     6901 ggcttataat ataatctaat attataaata aaggagttga aaaaatggct ggagctgata
     6961 taggcataga tttaggtact gcaaatgtgc ttgtttatgt tagtggtaag ggaatcgttt
     7021 tagaagaacc gtctgttgtg gcgatagaca acagaacaga ttctgtttta gctgtgggag
     7081 aagaagctaa aaagatgata gggagaacac caggtaatat agtcgctata agacctttaa
     7141 gagatggtgt aatttcagat tatgatgtaa ctgagaagat gttaaaatct tttatagata
     7201 agatagttga taaaaaggga tttggaagat tttttatgcc aagaattatg gtatgcgtac
     7261 caacaggtgt cacagaagtg gaaaagagag cagtagaaga tgctacgaga caagctggag
     7321 ctagagaagt atatataata gaagaaccaa tagcagcagc cataggagct ggtgtagaca
     7381 tatcacagcc taatggtaat atgattatag atattggtgg aggtactgta gatatagctg
     7441 taatatctct aggaggagct gttgtaagtg aatctataaa ggttggtgga gatagatttg
     7501 atgatgctat agttaaatat atgaaaaaac aacacaatct tcttatagga gaaagaacag
     7561 cagagaaaat caagtttgaa ataggttctg catttaagag agaagaagaa aaatatatga
     7621 agataacagg aagaaattta attacaggac ttcctagttc tataactata aattcaacag
     7681 aaatgttgga agcacttaga gaatgtgttg agcaaatagt agttgctact catgctgttt
     7741 tggaaaaaac gcctcctgag ttagcagcag atataggaga tgttggtata ataatgactg
     7801 gaggaggttc attattatat ggattagata aaataataga acagagaaca ggaataactg
     7861 ttacaatagc agatgaacca ttatcttgtg ttgcaaaagg tacaggaata gctttaggtt
     7921 caatagacct acttgaaact ggcgggtctt tcaaaagaaa ataattagga gagtttagaa
     7981 tgttaaatat agatgaaata aaaaaattaa taccacatag atatcctttt ttattagtgg
     8041 acaagattac agagctagaa gttgggaaaa gagctgttgg tataaagaat gtaacagtta
     8101 atgaaccatt tttccaaggt cactttccag aatatccttt aatgccagga gtattaatag
     8161 tagaagcttt agcacaagtg tgtggagtgg caatgatgtc tgtagaggaa aacaaaggaa
     8221 aactaggtgt atttgcaggt atagataaag ttagaatcaa gagagaagta agaccaggag
     8281 atacattaac tatggaagtt gaaatgacaa ctcttagaag aaatatagcc aaggcagatg
     8341 ctaaggcata tgttggtgaa gaacttgtct gtaaagggga attaatgttt gccttagtag
     8401 aaaaataaaa acttgaaata taaaagtaaa aaggtagata atttggagta tttaatcaga
     8461 tactctaaaa tatctacctt tttatataaa gaattttatc atttagttta tatttagatt
     8521 aggtggatac taataaagcc aaggctattg tttcagctaa gtctaatata aagctaagac
     8581 gtatattatt aaatgaaagt ttattatttt catcaatttt atctacaatt cctactatag
     8641 aataatttcc tatttgaggt agttttttgc caacaccttt tccgggcagg ataggtcctt
     8701 ctctaatctg tatattacct atgttactct gcgaccccaa gcaagcatct atagccaaga
     8761 agttaccttg tatatgtgta ttttttatag tatctaaaga ctcatatata tttaaggcgt
     8821 gaatagggtt atctagtgta ccgtaaacgg ggtatttaaa gttactgttc ttaagtattg
     8881 ttccaactaa agggcctaaa gtatcaccta tagccctgtc tgttcctatg caaacaacaa
     8941 tcgtattttc attaattata gtttttagaa ctgaacttag catctgtata acatcatcat
     9001 cgctgtaatt tactttagct aaatacaata ggaacacccc cttcaaaaaa atatatgaat
     9061 aaaaagcatt aaaaagacct aactttaaat ttcagataga tagaaaattt tatttgtctt
     9121 acaaaaaaag gaatagaaaa aatatgacta aaaatattga caaaatttta aaaaaatagt
     9181 aagctagtaa agtaaaacaa aacttaaatc ttgattacct tatcaagaga ggctgaggga
     9241 taggccctgt gaagcccagc aaccacccaa atgggaaaag gtgctaattc ctacaagaca
     9301 aaagtcttga aagatgaggt cagttaatta gtatgtaatt acgattatta acctcttctt
     9361 ataaaggaga ggttttttat tttgagtaaa tttctaaaat taaaaataag gtaaaaccta
     9421 taataaaaac taagaataaa taagggggaa taaaaatggc aagacattta tttacgtcag
     9481 aatcagttac agaaggacat cctgataaga tatgtgacca aatatcagat tcaatattag
     9541 atgcattatt agaaaaagac ccacaatcta gagtagcttg tgaaactaca gttactactg
     9601 gtttagtttt agtagcagga gaaataagta catctgctta tgtagacatt cctaaattag
     9661 taagagaaac agtaagagaa attggatata caagagcaaa atatggattt gattgtgata
     9721 cttgcgcagt tataacttct attgatgaac aatctggaga tatagctatg ggagttgatg
     9781 aaggcctaga aagtaagact ggagaagaga tagaagaaga aatagaaaaa gttggagctg
     9841 gagaccaagg tataatgttt ggatttgcat gtaatgagac tccagaatta atgcctcttc
     9901 caatatcttt ggcacacaaa ttatcaagaa gacttacaga ggttagaaag actggtctag
     9961 ttgattattt aagaccagat ggaaaaactc aagttactgt tgaatatgaa ggaagtaaag
    10021 ctgtaagagt acatacagtt cttatatcag ctcaacattg tgaaacagta tcaaatgata
    10081 aaataagaga agatttaatt aatcatgtta ttaaagaagt tataccagca gaattacttg
    10141 atgaagatac taaaatttat ataaatccaa caggaagatt cgttatagga ggaccacaag
    10201 gagatacagg tcttacagga agaaaaataa taatagatac ttatggtgga tattctagac
    10261 atggtggagg agctttctca ggaaaagacc ctacaaaggt tgatagatct gctgcttatg
    10321 cagctagata tgttgcaaaa aatattgttg cggctggtct tgcagacaaa tgtgagatag
    10381 aacttgcata tgctataggt atagctagac cattatctat atttatagat acttttggga
    10441 caggcaaagt ttcagaagaa aaacttgttg aattagtaaa taaacacttt gatttaagac
    10501 caggagccat aataagagac ttagatttaa gaaagcctct ttataaaaag gttgctgctt
    10561 atggtcactt tggtagaact gatatagatt taccttggga aagaactgac aaggttgagc
    10621 agttaagaaa agatgcttta ggtgaataat ttttaactaa aaagctgtta gaatgtaatt
    10681 ttacgattac tttctaacag cttttttatt atgagttaaa tatttttaat aaatgttaat
    10741 ttatcatcat ataatgaata aacagtattt aatctggtca atacatttta tataatacta
    10801 tactaaattt atgcatatta tgggatatat gttaaaggat ggttaagaat gtgttaacta
    10861 atgttaaata attaaaaata tattgaaata tcataataat gagtctaata taatcttaat
    10921 aaacttacac tttaaaaata attttaattg gggggagtag tgtatgtcag gcaaagtaaa
    10981 tattaaaacg gttataagtt ttgctggagc ttatgttgct actgtaatag gttctggatt
    11041 tgcaactggt caagaaatac tgcaattttt tacattttat ggatatgctg gtattatagg
    11101 tggaataatc tctatggtac tattttcatg gtttggagca gaggttatag ataagggaag
    11161 agaattgaaa cttaaggagc caataaaaat ttatcaagta tattgtggaa aatatcttgg
    11221 aacatttttt gaatggtttg gtccattgtt tttatttgga acattagtaa taatgattgc
    11281 aggagcagga gctacattat cagagtacta tggattaaat ccatatgtag gtaggattgg
    11341 tatgacaatc gtttccctaa taactgtttc attaggtttg acaaggcttt ctaaaatact
    11401 aggtaatata ggacctataa taataatatt tacactttta gtaggagcaa ttagtttatt
    11461 tagcaatatt gatgctttat caaatgctgg aaatatggtt gatagtttaa atattaaaac
    11521 tgctacatca aatggatatt tctcaggagt actttatact tgttataatg taataatagt
    11581 aataacattc ttgacaggaa tgggagcttc tgcagtaaat aagaaagatg ctgtgtgggg
    11641 tggtatagta ggtggagtag cacttatggc agcagctata atgatgaatt tggcattact
    11701 ttcagacata ggaaatatat acacaaaaga gataccagca ctttacttag ctgataagat
    11761 atctccaata ataggtattt tattctcagt agtactttta ctaggaatat acactacagc
    11821 tgtaccattg ttatggtcag taactaaccg atttgtagaa gatgaccacc ctaaatttaa
    11881 aattataaca atagtagtaa gtatattagc ttgtatagga ggtctactgc catttgataa
    11941 gttagtaggt acactatatc catatacagg ttacatggga attttaattt tactatgtat
    12001 gctttataga agaattacta aaactgaggg gtacaaggag aataaatctg aaataagcta
    12061 gtactgtaat atacttatga aatttaattt atactctaaa tatggagtaa ttaaaataaa
    12121 atagctattt aaatatggta cctgtatttc atggtaccat attttatgga tgcagatttt
    12181 ttttgtttct gataaaatgt ataatagttg gaaattacgt taagtataaa aatataaaac
    12241 ttttctacga ttatcatagt tttaatatat aaaattatac taacatttaa atggagcgat
    12301 tattagtatt tttaggagat aaaaatggaa aaattagaag gaatgataag tgaaatagtc
    12361 tttaaaaacg aagataatgg ttatacaata gctcatctgg taaatgaaaa tgatgaaatt
    12421 gtcgttgtag gatgtatgcc tactttggca attggagaaa gcatagaagt tgaaggaaag
    12481 tgggtaaacc ataagattta tgggactcaa tttgaagtga atagttttat gccagtaaca
    12541 ccatcatcct tagaaggaat ttatgtttac ttatcttctg gaatgataca tggtattggt
    12601 gaaaaaatgg ctaaaagaat aattgataag tttggtgtag atacgttaga ggtgatacaa
    12661 aattcaccag aaaaactaca agaagtagaa ggtataggga gtaaaaaagt aaaacaaata
    12721 gtaaaaagtt atgaagaaga cagagaattg agaaatataa taatacagct atctcctttt
    12781 ggaataacac caaattactg cctaaaaata tataaaaaat ataaaagcag tgcaatagaa
    12841 gttataaata aaaacccata ccaacttgct gaagatataa gaggaattgg atttaaagta
    12901 gctgatagta tagcaaataa aattggtata gataaaaatt ctaaggatag aatttgtcag
    12961 ggaatcttat acactttaaa taaatcttta agtaatgggc atacatattt accagagcat
    13021 gttctaatac aagattcgga aaaattattg gagctaaatg gagaaataat aaaagagtgt
    13081 gtaatgatgc tagtttataa tcaaaaaata catgtagaga aagtaaacaa tgaaaatctt
    13141 atatacctta tgccatacta tttagctgaa aatggagtat gtagtcaaat agtaaaatta
    13201 tcacagtatg aatttgaaga cttaaaaata gatatagata acgagattaa tgttttagaa
    13261 gaagataaga aaattaagtt agcagaaaaa caaattttag cagtcaaaga atctgttaat
    13321 agtggcgtat taattataac cggtggtcca ggaactggta aaacaactac cattaatgct
    13381 atcatagata tatttgaaaa taatggtaaa agcgtgactt tggcagctcc aacgggaaga
    13441 gcagcaaaga gaatgagtga aacttctaat aaagaagcaa aaactataca taggttgcta
    13501 gaaatgggat tttcaacaga tgatgattta acttttttta aggatgaaga agacccaata
    13561 aattcagatg taataattgt tgatgaggta tcaatggtag acattatctt aatgtacaat
    13621 ttacttagag ctataaagtt aggaacaaga gtaattttag ttggagatag tgaccaatta
    13681 ccttctgtag gtgctggaaa tgtacttaag gatatgatta attctaatat tataaatgta
    13741 gttaaattaa atgaaatatt tagacaagcg caagaaagta tgataattgt aaatgcccat
    13801 aagataaaca atggagaacc actttatcta aatacaaaag gtaaagattt cttttttata
    13861 agaaaatcaa ctaatgaaga aattttaaat gaaataatag gattggttaa tgaaagatta
    13921 cctaaatttt ataaagttga taaattaaaa gatatacaag ttttatcctc aatgagaaaa
    13981 ggtgaattgg gagttactaa tctcaatata gagttacaga agtatcttaa caaaaaagaa
    14041 aaatttaaag ttgaagaaag tttttctaaa agattattta gagttggcga taaggtaatg
    14101 caagtaaaaa ataattatac aaaaaaatgg gaaacagaag accaaaaaga aagtggagaa
    14161 ggtatctata atggagatat aggatatgtt tatcacatag ataaagataa aaaaactatt
    14221 tatatattat ttgaccagac taaaattgta tcatacctat atgatgaatt agatgaaatt
    14281 gaccatagtt tttgtacaac aatacataaa agccaaggaa gtgaatttcc agttgtagta
    14341 ttgccaatag cttgggctcc tcctatgtta cttagccgta atttattata tacagcagta
    14401 acaagagcaa aaaaattagt tgtattagtt ggagatgtga aatatcttga atatatgata
    14461 aaaaataata gagttaatca aaggtattca aatttaggat ataagctaaa taaatttaag
    14521 caagaagggc tgttgataga ataaatatga aaatatgcaa tgataatttt attaagaatt
    14581 ttaaaaatat gattaataaa tgtttggatt ttatatatcc tgagaatata agttgcataa
    14641 tttgtgataa atccataaag aaaacaaata cttattcaat atgtaaaagt tgttttaaag
    14701 aaatgaattt tatacaagat ggttgcatga agtgtggaaa accaataata cgtcattcaa
    14761 ttgaaaaaga atttattgaa gaatgtagtt attgttttaa taaagacttt tattttgata
    14821 aatcaatatc ttgtattgaa tacaatgatg tgacaaaaaa gatagtgcta gggctgaagt
    14881 ataaccaaaa aacctttatg gctaagtata tagctcaaat aatgaaagaa aaattatatt
    14941 tagaaaacat aaaatttgat tatatattat ttgttccact tcataaaaaa aggctaaata
    15001 aaagaggttt taatcaggca caaaaaatag catttaattt aagtaaaata gtaaatattc
    15061 cattattgga ttgtataagt agaaaaaaat atacaagaat gctatataaa ttgaataaga
    15121 aagaacgaaa agaagaatta aaaaatgtat ttgttgttaa agacaatgtt aaattaataa
    15181 ataataaaaa tatactttta atagatgata tatttactac tggtctaaca acaaacgaaa
    15241 tttctaaact tttaaagtta tcgggtgcta ataaggtttt tgtattgact ctacttacaa
    15301 aagcaaatga taattatatt atggaataat cttatatatt gacaatttta atttaaaata
    15361 ttaaaatgaa taagtgatat ttaggtctgt ggttgaaagt ccaagccagt cgcaggcaaa
    15421 gggatccacg taagttaaca ctaaaaattg ggttaatgat catggtgcgg cttagaagta
    15481 agacctaccg ataataaaat cgagagagag tagtagtgcg gcgaacccaa gcgaaccctc
    15541 cagtaggcga gtgtggggtc aaaaaccagg tcagctaaat atcgtattaa aagggagcta
    15601 gcataccttt atgtatagct cttttttata tataataaat ttaggttgag tcataaagag
    15661 gtgatatgtt tgaataaaag acaggaaaac ttattaacaa cgttgctatt aaaagaagag
    15721 tttataaatg ttaataagat tgccaatgat tttgagtgtt cagaaaggac aataagaaat
    15781 gattgcaaat atattgatga atggttatct actttttgta atgcttatat caaaagaaaa
    15841 cctaatattg gaattaaatt tagtggagat ggaacagaca aaatactggt aaatcagaag
    15901 ttgcgaggtg aagttaaaag agtaaatagt gagcttcata agcaagttga gatattaaat
    15961 ttactacttt gtaataataa aaaagttact ttaaatgatt tatctaataa gttgtacata
    16021 aataaaaata ttgtcagaga agaaataagt aaattatcag tggcattaaa taattataat
    16081 ttaaatgtct cgactaaaaa aggcagtggt atatatattg gaggggatga gaaagacata
    16141 agaataatgt tagtatcatt cttatttaaa tacatagata aatacagatt aaacatagat
    16201 gaaatagagt acttccatat agtagatata ataattgtaa aaaacataat gtttactata
    16261 gaggaggata tggatataag acttacagat atatcattca agcaattgat gctattttta
    16321 cttataaata taatacgaat aaggctagga aattctttaa aagtatcaaa tactaagaaa
    16381 gagcttaagc taaaaatgct gatattagat atagaagatg aattgaaatc taatttatcc
    16441 atagtattaa attatgaaga aaaattgttt atagagtctt taatattggg tatgaacaaa
    16501 caaataaata gtagtaatat taagaaatct ttatatctaa atgaagaatt agcaagttat
    16561 acaaaaaaaa ttataaattt agtatcagaa gaatccggaa taaattttaa taatgatata
    16621 ttactttatg aacaattaat atgtcatttg aatgttacaa tgcaccaaat gaaaagcaat
    16681 gtttacttag aaaatccact tttagataac ataaaaacta aattttgttt tttatttaca
    16741 gtaatatcaa gttcaataga aattgaatta aaaggaaaac aaataacaga agatgaaatt
    16801 ggttatctta cacttcactt tcaaacctct ctagaaagaa aatacagcaa aagggaatca
    16861 aataaaaagg caagtattgt atgtccattt agttttggag taagcatgct attaaaagta
    16921 aagatagaaa agagatttga taacataaaa attattgaaa cattaagaga ggaagattta
    16981 aaaagagata acttcaataa gactatagat tttataattg catttcaaga gtatgaaaat
    17041 atccaaaaac caatttttat aacaacacca ttatttactg atgaggatga gaataaactt
    17101 aaagagttca caaacaaaat aaaagaaaaa gacacttcat ataaacttat gaacagatta
    17161 atgatgtctg attatttaat aagagagtta gaacatgatg atatttatga agctataaca
    17221 tatttaacta atttattaat tgaaaaacat tatgcagaaa aagagtattt acaatctatt
    17281 ataacaagag aaaagtcata tccaaccaat gttggaaaag gaatattatt ccctcatgga
    17341 gatatgaaat atataaaaca atctgtttta tgttttgcaa ggttaaaaac accaataaga
    17401 attagaaatg gaaaggatat aaagattata cttttgttag catataaaaa agatgatgat
    17461 agaaaagtat ttagagaatt atttaaagaa atatctaatt taacagagga tgaaaatatg
    17521 ctagatattc taagtaaatg tgacattgaa aaagtaaaag atattcttat ataaaattca
    17581 tagtgaacta tggataagca caaaattttc catgtgatgg aaaaagttgt gcatgttttt
    17641 ttgtttttat aagatattat atgtttgtaa ggtataaata atctaaaagt agagaagcaa
    17701 cttaggagga aaaaatggaa gaaatagttt taaagattat aattcatgct ggaaatgcaa
    17761 aatctatgct ttatgaagca cttgactatg caaaggaaaa cgattttaaa aaagcagatg
    17821 aattaattga aaatgcaaat gaagaaattt taaaagcaca taaagtacaa actgaactta
    17881 tacaaaagga agctggggga gataaatcag atatatctat tttattgatt cactctcaag
    17941 accatttgat gacttgtatg agtgagagaa accttataaa agaaatgatt atgttaagaa
    18001 aagaaattca aaaattaaaa taaaaaaatt aagggggatt taaaaaatga aaagaaaagt
    18061 atatttattt tgtagctttg gtatgtcaac aagtttactt gcagataaaa tgcagaaggt
    18121 agcagatgaa cacaatttac caatagaagt agaggcattt ccgatagcag aaattgacaa
    18181 aatagttgaa gaaaaaaatc cagattgtat attactagga ccacaagtta aatacatgct
    18241 aaaggaatta aaaccaaagt ttgaagctca aggaaaactt atagatataa tcaatgaagt
    18301 tgattatgga actatgaatg gggaaaaagt attaaaactc gctataaagc taataaaatc
    18361 caaacaagcg tagaattata gtaaaaaata ataggaaatg agggtagata gatgaataga
    18421 ttggaaagaa tacttatgcc attggctgaa aaaataggta aaaataaatt attaattgca
    18481 attagagatg gttttttaat atcatcacca ttattaataa taggttcatt atttttatta
    18541 gtagcaaatt ttcctataaa aggatggaat gaatttgtag gtcaaatttt tggttcagat
    18601 tgggctgtaa aattgcaaca accaactgta gcaacatttg aagtaatgac tctacttgca
    18661 gttttaggaa ttggatattc ttatgcaaag caaatagatg tagacccaat agcatcagca
    18721 gcagttgcaa tagttgcctt ttttataata acaccatttg taataccata tacaccagaa
    18781 ggaacagaat cagtctacat ggtaacaggt ataccactag gttggatggg ctctaaggga
    18841 atgtttgtag gtatgataac agcaataacc tctgtaaaat tatttgctgc agttgtaaaa
    18901 aaaggatgga cattgaaaat gccagatgga gttcctccaa ccgtatcaaa atcatttgca
    18961 gcattaatac caagtgcaat agttatggta gttttctttt tagttaagat agcttttgaa
    19021 gctacaccat atggaagtat acatgaattt atatttaagt ttttacaaat gccattatta
    19081 aaattaggaa atagtttagg tgctatggca atcgcttata tattcttaca tttattctgg
    19141 ttctttggaa taaatggaag tagtgttgtt ggggctgtgt ataatccaat attaaaaatt
    19201 ctatcagctg aaaatttagc tgcttttcaa gctggttcaa aaataccaaa cataataaca
    19261 ggtcaattcc aagatatgtt tgcgacattt ggtggagcag gtagtacact atcattagtc
    19321 atagctatgt tattaatatg taaaagtaaa cgtataaagt caatgggaaa actatcaatt
    19381 ttaccaggaa tatttggtat aaatgagcca ttgatatttg gtctaccaat aatgcttaac
    19441 ccaatactat tgataccatt tgcaatagtt ccaacaataa atataataat agcttatttc
    19501 tgtatgtcag caggattagt gcctcttaca aatggagttc agttaccgtg gacaactcca
    19561 attatattct ctggtttttt aacaacagga tggcaaggtg cagtcttaca agtagtgctt
    19621 cttatactag gaatatttat gtatatacca tttataaaaa tgctagataa gcaatactta
    19681 agagaagaaa atgcaactgt tgaagaggaa gatgatgata tatcttttga tgatttagta
    19741 ttataggagg aagatgatga agaaaatagt tatgatattg gatcaaatac aagctggagc
    19801 tggaggaaaa gagaaaagta atatacctcc tgctggaaaa tcaagcccat taggaccagg
    19861 tataatgatg gagcaatttt taaatgaatc taaggtaata gctaccttat tttgtgggga
    19921 tgaatttttt gtaaataatg aagaagaagt aactagtaag atgatagcta tggtaaaaaa
    19981 attaaaccct gatgtagtaa tctgtggacc aagctttaat tacgaaaact tttctaagat
    20041 gtcagcaata ctgtctaaaa atataaatga taaaacagat ataccagctt ttgcagctat
    20101 gtcagaagaa aatatagatg tgataaacga atataaaaat gacatatgta tagttaagac
    20161 tccaaaaaaa ggtggaattg gtcttaatga ttcattaaat aacatatgta aattggcaaa
    20221 agcaatagca aataaagaag atataacttt gatgaaagaa gaattttgtt attaataaga
    20281 gtattaatta ttagtaagtt taaatattat actatttata ataagcatac attagtaaaa
    20341 tctatataat ttaaggaggg gaattttaac atgtggggaa tgatagcgac atggagaatg
    20401 gccctagaag gaataactga ggcatcagaa catttagaaa aaggcatgga agcaggtgat
    20461 gctgtagagc ttgctgtaag aagagttgaa gactatccat tctataaatc ggttggatat
    20521 ggtggacttc caaatgaaaa ttgtgaggta gaacttgacg ctgcatttat ggatggtaac
    20581 acattagata ttggagcagt tgctggtata agagattatt ctaatcctgt cagcatagct
    20641 aggaagttaa gttatgagaa ggtaaataat tttttagttg gaataggtgc tgaagattat
    20701 gctcataaaa atggatttga aagaaaaaat atgttgactg atagagcgaa gttacattat
    20761 aaaaagagaa aaaaagagac tttagacaaa ggattaagtc catatgctgg tcatgatact
    20821 gttggtatga tatctttaga caaaactgga aaaatgtgtg cagctacatc aacaagtgga
    20881 ttgtttatga agaaaagagg tagaatagga gattctgcac tatctggttc aggattctat
    20941 gttgatagta gtataggagg agctacagct actggtttgg gagaagattt aatgaaggga
    21001 tgtatatctt atgagatagt tagacttatg aaagaaggga agcatccaca agaagcatgt
    21061 gatattgcag taaatgaact tgataaacag cttatcaaaa gaaggggaaa agctggtgat
    21121 ttatcattag ttgccatgaa taataaaggt gaatggggag tagctacaaa tatagctgat
    21181 tttacttttt cagtagtaac taaagaagaa tctcctactg tatatatttc aaatagagta
    21241 gatggaaaga ctatacataa ggttatatca aatgagtgga tggaagcata tgaggctaga
    21301 ataaaagcac caatagaagt aagtgagtaa agtagtggtt acataattaa aatagagttt
    21361 tataataagg agatttttat gaatatcata agtaataaaa tagatgagtt aaaagaagat
    21421 ttattaagtg atattataga tattgtaaaa atacctagtg tcaaagggga gtcagaaaat
    21481 ggcttccctt ttggcgaaaa agtaggggag gcacttaata aagcattaga aatatcagaa
    21541 aaattgggat ttaaggttag aaacttggat aattatattg gttatgcaga gcatggagat
    21601 agtgatgatt atgtttgtgt aattggacat gtagatgttg tacatgaagg agatggttgg
    21661 aagcatcagc cttataaggg agaagaaact aatggaagaa tttatggacg aggagtacta
    21721 gacaataaag gacctataat gtctgcctta tatggattat atgctattaa agaattaaat
    21781 ttaaaattag ataagagagt tagaataata tttggtacaa atgaagaaag tggatttgaa
    21841 gatataccat attatttaga aaaagaaaaa gcacctatta tgggatttac accagattgt
    21901 aaatatcctg ttgtatatgg tgaaaaaggc atggcaaaga ttagaataaa aagtaaaatc
    21961 aattatgaag aagatgtata cttaggtttt atagaaaata tgtctgaaaa tgtgcttgtt
    22021 acatataaag aactgaatat agaaaatagt gatactatat tagatataaa ggtaaaatac
    22081 gattttagtt ataaattgaa agatgtattg gatgaaataa aagctagttt tccaaatagt
    22141 atcgatatag aggtaatttc taattttaat cctgtatatt ttgataaaga gagtaatctt
    22201 gttaaaaagc ttcagctagc ttatgaaagg gttacatcat tagatggaac tccagtaaca
    22261 actaatggag gtacgtatgc aaaagtaatg ccaaatatag ttccgtttgg accttcattt
    22321 ccaggacaaa aaggaatagc tcataatcct gatgaataca tggatataga agatataata
    22381 ttaaatgcaa agatatttgc aaatgcaata tatgaattag caaaggagta gttatgttag
    22441 aaataatagg aatgtcagta gaagacgcta aaattataga agattgtggt gcagatagaa
    22501 tagagttagt tagtgcttta actgaaggtg gattgacacc aagttttggt cttatagaaa
    22561 gtgttgttaa cagtgtaaag atacctgtga acgtaatgat aagacatcat gcgaaaagtt
    22621 ttgtatacag taaagaagat ataagtataa tgcaaaaaga tataagtgtg gttaaagaga
    22681 ttggtgctaa tggagttgta tttggtgtat tggataaaaa caatagtata gatgagaaaa
    22741 atctaaatgt tttattgaaa tgttgtgata atcttgatgt tacatttcat agagcaatag
    22801 atgaatcaaa tacaatagat agtgttaaaa ttttgaagga ttatgataaa attacgaata
    22861 tattaacatc aggagggaaa ggaagtatag ttgataacat acaaatgata aagaatatga
    22921 tgcttagttc taatcacata aaaattcttt taggtggagg tcttaatttt aataatatag
    22981 aaaagataaa ggaattaact aaggcaagta attttcattt tggtacagcg attagaataa
    23041 ataacagtcc ttttgaagat atagatagac aaaagcttaa acaactcgta aatataattt
    23101 caagatagta tatgaatata aaatacttag tttaaataaa gagagtaagt taattataat
    23161 ttgggtatat gaatgttaat aggtattaaa tatgaaatta ttgttgagta tgctttataa
    23221 cttttaagta gttttaaata taaataatga aagaaaagat agattatgga ggttttagag
    23281 ggtttatatt tattaaaaaa ttataaaggt atattggcat ataatacaca taatttccta
    23341 aaattaccat cttatgacat gaattcacat attaataaac aattaatgga gatttttgtg
    23401 gatagaaata ggagtaaaaa tagctttaaa taaacaaaaa caagagttat taacagtttt
    23461 atccacatta tccacaggtg tttgtaataa tattaatcca cataagtatc aatgtaacta
    23521 aaaatgataa ataattctat caattgaata gaaaaaatca taaaagtaaa taataaaaag
    23581 aggattatga gagttcgtgt agaatatatt attaaagtat aaattttctt atactggcat
    23641 aattgaaggg agatgtattt atgaacataa ttatatctgg aaaacaaatc gaattaactg
    23701 atgcaataaa aaataaaatc gaaactaaac taagtaagtt agataattac attcatccag
    23761 acactgatgt aaaagttaca gtaagtgcga gaaaagcaag acaaaaaata gaagtaacaa
    23821 tagctactgt aaatggtcct ataattagag cagaagatat gcaggaaaat ttatacacag
    23881 ctatagatgt tgtatatgat aaattaagta aacaattaaa aaaatataaa aagagattac
    23941 aagataaaca taaagacaac aagagtataa gattccaaga tgcagagata aatctagctg
    24001 atgaacaaga ggattatggg gatgaaaatc aagaattagt aattcaaaga cgtaagaaat
    24061 ttagtgttaa gccaatgagt gaagaagaag ctgtattaca gatggaatta ataggacatg
    24121 atttttatat gttcaagaac atagattcag atgaaatagc agtagtttat aagcgtaata
    24181 atggtggata tggtataata gaacatgaat aaagcaattt agatttaatc atattagcta
    24241 tcgataaata aattatcgat agctttttaa attaatatta aaagtatagt ttttatggta
    24301 aaatgaataa tagtacaata aagaacgagg agagatgtaa aatatgagct ttatggataa
    24361 tttattcaac atggcagata aaaaagaatt aaaaaagttc aataaaactg ttgatataat
    24421 agattcatta gaacctaaat ttgaatctat ggcagactcg gaacttaaaa atatgacaaa
    24481 tatatttaaa gaaagattag caaatggtga aagtatagat gatatacttc cagaagcttt
    24541 tgcagtagtt agagaagttt ctaagagagt gttaggactt agacactaca gagttcaaat
    24601 gattggaggt atagtactac atcaaggaag aatagcagaa atgaaaacag gtgaaggtaa
    24661 aactttggtt gcaactgctc ctgtttattt gaatgcgctt actggaaaag gtgtacatgt
    24721 tgtaacagta aatgattacc ttgcaaaacg tgatagagac caaatggcaa aaatctatga
    24781 gtttttagga atgagtgtag gcgttattat acacggtcaa aatccaaaag ttagaaaaga
    24841 acaatatgat tgtgatataa cttatggtac aaataatgaa tatggatttg actatctaaa
    24901 ggacaatatg gtaatacaca aagagcaaag agttcaaaga ggattaaatt atgctatagt
    24961 ggatgaggtt gactctatac taatagatga ggctagaaca ccacttatca tatctggacc
    25021 tggagacaaa tcaactcact tatattcaga tgcaaacaca tttgttttaa ccttaaaacc
    25081 agatgattat gaattagaag aaaaagataa ggctgtatct ctaacagcat cgggtataca
    25141 aaaagcagaa gtgtatttta atgttgataa tataacagat atatctcata cagaattata
    25201 ccatcatata aatcaagctt taagagcaca tgtaataatg aagaaagatg ttgattatgt
    25261 tgctaaagat ggagaaatag taatagtaga tgagttcaca ggtagactta tgtttggtag
    25321 aagatattca gaaggtttac atcaagcaat agaggctaaa gaaggtctta aaatacaaag
    25381 agaatctaaa acactagcta ctgtaacatt ccaaaattat tttagaatgt acaaaaaact
    25441 ttctggtatg actggtacag caaaaacaga agaagaagag tttaaagcaa tctacaaaat
    25501 ggatgttttc caagtaccta ctaataagct tatgataagg gaagacttac cagattgtgt
    25561 atacaaaagt gaaataggta aatttaatgc tgtagcacaa gaaataattg aaaggcacaa
    25621 agtcaatcaa ccaatacttg taggtacagt atcaatagaa aaatcagaat tattatcaca
    25681 aatactaaag aaaaagggca taaagcacga ggtattaaat gctaagcatc atgataaaga
    25741 ggcagaaata atagcacaag ctggtagact tggagctgtt acaatagcta ctaatatggc
    25801 tggtcgtggt acagatatag ttctaggtgg aaatccagac tttttaacta agagagaaat
    25861 gagaagaaat ggatttaaag aagaaatagt aaatagagta gatactccaa tagaaggtat
    25921 acctgtaaaa ggtaatgaaa ttctatttga agctagagaa gagtatgaaa aactatttga
    25981 aaagtttaag caacaaacac aagaagaaca aaaacaagtt gtagaagcag gtggacttgc
    26041 tataataggt acagaaagac acgaatctcg aagaatagat aaccagttga gaggtcgtgc
    26101 tggacgtcaa ggtgacccag ggagttcaag attctatata ggtcttgatg atgaccttat
    26161 gagattgttt ggtagtgata gaatatctgg tattgtagat aaaataggtc ttgaagaaga
    26221 tatgccgata gaacatagaa tattatctaa gtctattgaa ggagcacaaa agaaagtcga
    26281 aggtaaaaac tttggaataa gaaagcatgt acttcaatat gatgatgtta tgaataaaca
    26341 aagagaaata atatatgcag agagaaaacg tgtattagaa ggtgaagatt tacaagaaca
    26401 aatacaatca atgactcatt ctataataga agaagcagtt actctttata cacaagataa
    26461 aggatttgat gaagaaggat ttaaagaaca tatgtataat ctgttcttgc caaaaggtag
    26521 catagaaata ccagaaatag aaaaacttaa tccagttgaa ataacagaaa aagtttatga
    26581 aatagctatg aagatatata cttcaaagga agaacaagtt ggctatgaga gaatgagaga
    26641 agttgagaga gtaatcttac ttcaagctgt tgataaccat tggatagacc atatagatgc
    26701 tatggaccaa ttacgccaag gtattggtct tcgtgctgta ggtcagcaag acccagttat
    26761 tgcttataaa atggaaggtt ttgatatgtt tgatgaaatg aataaacata tcaaagaaga
    26821 tactgtaaga tatttattta atataacaat agaaactcca gtggaaagaa aagcagttgt
    26881 agatgttgaa aatctatctt ctccatcaga tggaacactt ccaacaagta aaactgttaa
    26941 aaaagatgaa aaggttggaa gaaatgactt atgcccttgt ggaagtggta aaaaatataa
    27001 aaactgttgt ggaagataat ctcggaggat taaatgttaa agttacaaga gtatagacat
    27061 agtatggagc agatggcttc aaatttagaa gaattgaggg tttctctttg acatagcttc
    27121 attgatgaaa aatatacaaa ttaatgaaga aaagatgaat aaacaagact tttggaatga
    27181 taatgaagtc gctcaaagag tacttcaaga aaataagtct ttaaaagaga cattagaaga
    27241 atatgaaagc ttaaaaagct tactagaaga tatagaagta ttaattgaaa taggtttaga
    27301 agaagatgat gattctgtag aaagagatat agaaaagtcc atagaatcaa tggaagaaaa
    27361 attatctgaa atgaaaataa agactcttct aaatggagag tatgataaaa ataatgctat
    27421 attatctata aatgcgggta ctggtggctt agatgctcaa gattgggctc aaatgctttt
    27481 gagaatgtat ataagatggt cagaaagtaa gggttataaa gttaagctct tagatataat
    27541 atcagaccct gaagcgggga taaaaacagc tacaattctt gtagaaggaa caaatgctta
    27601 tgggtattta aagagtgaaa aaggagttca tagattagtg agaatatctc catttgaccc
    27661 atcaggaaaa agacatactt catttgcatc tatagatgta acaccagagt tagatgaaaa
    27721 tatagaagta gaaattaatc catcagattt aaagatagac acatatagag cttctggagc
    27781 tggagggcaa catgtaaata caactgattc agcagttaga ataacacata tccctactgg
    27841 tgtagtagtt cagtgccaaa atgaaaggtc tcagcatcta aataaggaca gagctatgag
    27901 acttttaatg gcaaaattga tagaattaaa agagttagaa caaaaggaaa aaatagaaga
    27961 tatacaaggc aaatactcac aaataacttg gggtagtcaa attaggtcat atgtttttca
    28021 accatataaa ttggttaaag accatagaac aaatgctgag tttggaaatg tagatagtgt
    28081 aatgaatggg aatatagact tgtttattaa tgaatactta aaaatgaata aaatagttta
    28141 ataaatatgc actgtaatta agatatatgt ataagaaggt tagtgcttaa tatgcactta
    28201 cagcacttag gctgaggacg ataaccctca gccttcgttc tgttttgtta tacttatgaa
    28261 aaactaacat taggagtgaa taaattggat ataaatcaaa ttttaaaaaa agagtttaat
    28321 cttagagatg aacaaataaa taatacatta aaacttattg atgaaggaaa tacaatacca
    28381 tttatagcta gatatagaaa agaaatgact ggcgaaatga gtgatgttac actaagagaa
    28441 ttttatgaaa agttaatgta tttgagaaat cttcaaagta gaaaagatga tgtagttaga
    28501 ctaatagatg aacaaggtaa attaacagat gaaataacac aaaatataga aaaagcaaaa
    28561 acactacaag aagtagaaga tatatatgct ccatataaac aaaagaaaag aactagagca
    28621 acaatagcaa aagaaaaagg attagaaaaa ttagcattgt caatactaga gaataattta
    28681 gataatatag aaatagaggc aaagaattat cttgatgaag agaaagaagt tctttctatt
    28741 gaagatgctc taaaaggtgc tagagatata attgcagaac tagtctcaga tgatgctaag
    28801 attagaaagt atataagaga attagcttta agagaaggta tgatagttag taaaagtgcc
    28861 actgatgaga aatcggttta tgacatgtat tatgattata gtgaagcagt aaaaagtatg
    28921 cctccacata gagttttggc aataaacaga ggagaaaaag aaaacttcct aaaggttaag
    28981 ttagaaataa ataatgataa agttttaaat tacataataa acgaatatgt aaatgataaa
    29041 aatttcaaaa ataaagaaga aatcgtaagt tcaatagaag attcttataa aagattaatt
    29101 ttcccatcaa tagaaagaga aataagaaat catttaacag aaatagctca agaaagagct
    29161 ataagtgtat ttggaaagaa tgttaaaagt ttattgcttc aaccaccagt taaagacaaa
    29221 gtagttatgg gatttgaccc tgcatttaga actggatgta aaatagctgt agtagataaa
    29281 aatggtaaac tactagatta tacaacagta tatccaacag accctcaaaa tgatgtagag
    29341 ggagcaaaga aagttttaaa aggattgatt gaaaaatacg atatagatat aatttcaatt
    29401 ggaaatggta ctgcatctag agaatcagaa acttttgtat cagaaatgat aaaagaaata
    29461 gataacgaag tgcagtatgt gatagttagt gaagcaggag catctgttta ttcagcctct
    29521 gaacttgcaa atgaggaaca tccagatata aatgtatcaa taagaggagc tatatctata
    29581 gctagaagat tacaagaccc attagcagag cttgtaaaaa tagaccctaa aagtattggc
    29641 gttggtcaat atcagcatga tttaaacaaa aagagattag aagaagtact agatggagtt
    29701 gttgaagatt ctgtaaatag tgttggagta gatttaaata ctgcatcata ctccctacta
    29761 gaacatgttg caggaataag taaaactata gcaaaaaata taatagcata tagagaagaa
    29821 aatggagatt ttacgtcaag agcacaattg aaaaaagtaa agagactagg accacaagca
    29881 tttactcaat gtgctggatt tatgagaatc ttagagggta aaaatccact agataataca
    29941 ggtgtgcatc ctgaaagtta tgatatatgt aaaaaaatga ttgagataat tggatattct
    30001 ttagatgatg taaagaataa gaatatatgt gaaatagatg aaaaaataaa agaaattggc
    30061 ttgagagaat taagtgaaaa actggaagta gggcaagtta cgttaaaaga tatcataact
    30121 gaaatcaaaa aaccaggaag agacccaaga gaagaaggta taaaacctat acttagaact
    30181 gatgtcttaa aaattgaaga tatacaagag ggtatgactt taaaaggtac aataagaaat
    30241 gttgtagatt ttggtgcatt tgtagatatt ggaataaaaa atgacggatt agttcataaa
    30301 tcagaaatga gtaatagttt tgtgaaagac cctatgagta ttgttacagt aggtgatata
    30361 gtagatgtaa aagtcattgg aattgactta aacaaaaaaa gagttgcctt atcaatgaaa
    30421 aaatagataa gtttatgtat ggttatagta cttaaattct atgtttgtaa atgaggttac
    30481 tcgagtgtat aaatgttaaa aatttgtaaa agtatacagt aagaaaatat attaaaataa
    30541 gaacgatagt cttgaaaatc aggaggaaaa tgaatgattt ttataaaaaa tggtaaaata
    30601 aataccataa caaatgggat aattcatgga gatatactta tagatgaagg aaaaataata
    30661 gaaattggag aagatttgat agctccttta gatgtagagg taatagatgc tagtaataaa
    30721 cttgtgtttc ctggatttat agatgctcat actcatttag gtttgtggga agatggtata
    30781 gggtttgaag gagcagatgg aaatgaagag actgacccaa taacaccaca attaaatccc
    30841 atagatggaa ttaatccaat ggatagaact tttaaagaag cttttgaagg tggaataact
    30901 tctgtttgta caacccctgg aagtgcaaat gttatgggtg gtcaatgtat agctataaag
    30961 acatgtggaa aaagaattga taaaatggta ataaaaaatc cagttgcatc taaaatcgct
    31021 tttggagaaa atccaaagag ctgttatggt caggatgata aatctcctca aactagaatg
    31081 gctatagctg ctttacttag agaaaaccta aaaaaagcag aagaatattt agaggatatt
    31141 gatatgtatg agagtcatga tgatgaagac tgtgaaaaac ctgaatatga tataaaaatg
    31201 gaaagtttaa taccagtttt aagaagagaa attcctttta aggcacatgc tcatagagca
    31261 gatgatatgt ttacagcaat aagaattgca aaagaattta atttaaagct tacattagac
    31321 cattgtacag aaggtcatct tattgtagat gaattagtgg aagaagggtt tcctgtaata
    31381 gtagggccat ctttgtcaga aaggtctaaa tttgagctta gaaatttgac atttaataca
    31441 gcaggaatac tttcaaatgc aggtcttgat gtatgtataa tgacagacca tccagtaata
    31501 ccagttcaat atcttccaat atgtgcaggt attgcagtca aacatggtat gaaagaagaa
    31561 aaagcaatag aatcaattac gataaatcca gctaagactt taggaataga agatagagta
    31621 ggctctatag aagttggtaa agatgcagac ctagtaattt gggataattc tccactagag
    31681 attcaaagta atgtacttta cactataata aatggcaaag tagtgtatga gaaaaaataa
    31741 cttgacaatt attaaaaaat taactaatat aagagtgtaa ggaaaattaa aaaatcaaag
    31801 aagatcttcg gggcagggcg aaattcccta ccggcggtat agcccgcgaa ctacttaagt
    31861 ggttgatttg gtgagattcc aaagccgaca gtaaagtctg gatgagagaa gatatttatg
    31921 gaagataaat aagtttattt tagtttgttt aaactatatc cataaaaact cgaagatagg
    31981 gtcttcgagt tttttgtttt tcctaaaaaa tataaacata ttgattaggg ggaaataatt
    32041 atgcaaaaca cagccaaaag aggcaatatg atttcaacaa gaactttagt agtaatgtca
    32101 attttatctg caatatctta tttattaatg tttattcaag caccaatacc aggtatattt
    32161 ccagatttct taaaaattga cttatcagat attccagcaa tattcggagg aatgtctcta
    32221 ggaccatttg ttggatttgg aatagttgta gtaaaaaatg tgttacaagc aataacagca
    32281 acaacaactg gaggaatagg agaatttgca aatatattaa ttggtggttc ttatgtaatg
    32341 atactttgtt attcatataa gagaagtgga gatttaaaag gtgtattgat tggttttgta
    32401 ttaggaacaa tatctatgac tataattggt tcattagtaa attattttgt aatgttgcca
    32461 ctttatggtc aacttatggg actagatgct ataataggtt taggttcagc tataaatcct
    32521 caagttcatg atttattcac ttttgtaatt tggatgatag ctccatttaa tgtgctgaag
    32581 gctgttatac tatctttagt aacattgcca ctttataaaa aaatgggaaa tgtaataaag
    32641 aaataattag acaagaaaat ataaaattaa atgtattgaa tagccataat ttatttataa
    32701 cttcagtcct atattgtgat tgatatatta aatatattat ggctttatta atttatcaaa
    32761 aaatgtatat aaaataagaa atatttagac aaatttaaat tttaaaataa aggaagaatt
    32821 aaaacgatta actattaaaa tatgaaaaag gtatctgcaa tatacagagc gaatttataa
    32881 taaataaaaa ataaagttat tattaaaaaa atataaagat tagtaatcaa atttttaata
    32941 ataactaatt taataatgat gggagtgtat attcatgaac ttatctaaaa agataaaaaa
    33001 attattttta gatgataaag ggtattattt taatagtaat tggaaagata ttcatattgg
    33061 tatttataat acaaaattag gagattcttt aaagtatatc actaatgaat atattgaaaa
    33121 tctggaaagg gtaaaatatg actatcgtga attaaaaaat atagaaaatc aaactgatgg
    33181 tatgtgtatt ttagcaataa ggcagaatta caaggcatta gagtatgtaa aaaatcaaac
    33241 cgaagaatta tgtttagaag caataaagta taattataaa gcacttgaat atgtaaaaga
    33301 gcaaacagaa tatatatgtc ttgaggctat aaaaaaggat tgtaatgcac ttaagtatgt
    33361 acgaaataaa acagaaaggc ttattataaa agtaatacgt cattcttcca atatagatgt
    33421 tgtaagtata ctaaaggctt tagagactca aacaagaaga atatgtttag aagcaattaa
    33481 aaaagatggc aggtgtcttg catacgttag agaacagagt gaagaattat gtatagaggc
    33541 cattaaacaa aattataaag cattaaaata tgtagaaaat caaacggaaa aaatgtgtat
    33601 agaatccgta agacaaaatg gtatggcatt acaatatgta aataaacaaa ctgataaaat
    33661 atgtatagaa gctgtcaaac aagatggaag aagtctacaa tttgtcaata ataagacaga
    33721 agaaatatgt ataaatgcta taagatattt aaataaaaaa tataatatta aagatgtact
    33781 aagttacata gataagtata cagaagatat atgtatagag attgtaagac aaaatggaaa
    33841 aatgcttatg tatataaaaa atcaaacaga aaaaatgtgt attgaagcag taaaagagaa
    33901 ctataagtct cttaagtatg taaaagagca atctgagaga atatgtaaag aagcattgaa
    33961 gcaaaaccat aaagcaaaag agtatgtaaa aattgctatt gatgattgta tataaggtgt
    34021 agatacagcc atcaatagtg aaagataaaa aaagataaag acaagtactt tataataatc
    34081 taggcttata ctataattaa ttaagcagtg atataaattc acatgacgat tatatcaaaa
    34141 tggagatgaa ttgatggcaa aaatatattt agaaaatgaa aataaaacta gagaaatagg
    34201 atataaatta ggtaaacttt taaaagaagg cagtgttatc tgtttagtag gagatttagg
    34261 agctggtaaa actacaatga cacaaagctt ggcagattca ttagggatag aagattatat
    34321 aacaagtcct acttttacta taataaatga atatgaagga aaaatacctt tgtatcattt
    34381 tgatgtttat agaataggta gtagtgacga aatgtatgat attggttatg atgaatatgt
    34441 aaattcaaat ggaatctgta taatagaatg ggctaatcta atagaagata tacttccaaa
    34501 agaatatttg aatatagaat tgagatataa agatgacgga agagaaatga tattaactcc
    34561 aaaaggagag ttttataaag agatagttga ggagttgatt aaataatgaa aatactaggt
    34621 atggatacgt cttctatggc agcaagtgta gcagttgttg aagatgataa cttaatatgt
    34681 gagtttacag taaacaacaa aaaaactcat tcacaaaagc ttatgccaat gatagaaaat
    34741 atgttgagta tgagtgattt aagtataaaa gatatggatt tattagctgt atgtataggt
    34801 ccaggctcgt ttactggact tagaataggt atggccacag taaaagctat ggctcatgta
    34861 aataatatac caataatagc agtaaattct ttggaatctc tagcaaataa cataaatttc
    34921 tgtgatagaa agatatgttg tatattagat gcgcagaaaa atcaagttta ttcagctaaa
    34981 tacaagtttg aaaatggaga gatgatagaa ttagatggtg tagatgttgt agagtttgat
    35041 gctttagtag atgaaattgt atcaactaat gaagaattta taatagttgg agaagctgta
    35101 tacaaatata aagataagtt agagaatata aaaaatataa aaataccttc accagctaat
    35161 aatgtatcta acgcaggaag cttatgctct ttagcattaa ataaatataa taaaaatata
    35221 gatgtacata cttgttatac gataaatcct atgtatatca gaaaatctca agctgaagta
    35281 caatatgatg aaaaaatgaa gaggctaaat aatggaagat aatacaaaac taatagtaga
    35341 tgatataaaa atagaagaaa tgactacaga agatatagat gaagtttttg aagtagaaaa
    35401 aaattgtttt gaagattatt ggtcaaaaga gtcttttaga aaagagttgt ctaatgaagt
    35461 agcaaggtat atagtagcta agttaaatgg aaaaattgtc ggatatgtgg gaatttggct
    35521 tatacttgat gaagggcata taaataatgt ggctgttcat agtgactata gagggaaaaa
    35581 aataggggac aagttgataa aaggcatagt tgatttatgt aaagataata atattgcatc
    35641 tatgacatta gaagttagag catcaaataa aatagcacaa aatttatata gaaaatatgg
    35701 atttaaaatg ggtggaataa gaaaagaata ctacagtgat aataaagaag atgcaattat
    35761 aatgtggaac caattaaaag aggtgtagag tttatgagtg atataataac attagctata
    35821 gagagtagtt gtgacgaaac agctgcatca gttttaaaaa atggtagaga agtactttca
    35881 aacataatct ctactcaaat agagacacat aaaaaatttg gtggtgtagt tccagaagtg
    35941 gcttcaagaa aacatgtgga aaatattgat atagttgttc aagaagcttt agacaaagca
    36001 aatataggtt ttaatgatat agaccatatc gcagttacat atggacctgg actagtaggt
    36061 gctttattgg ttggtctatc ttatgctaaa gcacttgcat atactttgaa tattccactt
    36121 gtaggagtaa atcatataga agggcatcta agtgcaaact atatagagca taaggatttg
    36181 aaacctcctt ttataacatt aatagtatct ggaggtcata ctcacttggt tgaagtaaaa
    36241 gattatggca agtatgaaat tttaggaaaa acaagagatg atgcatctgg agaagcattc
    36301 gataaaattt caagagcaat gaatttaggt tatccaggag gacctattat tgataatcta
    36361 gccaagaagg gaaataaaca tgctatagag tttccaagag cctatttaga agaagatagt
    36421 tatgatttta gttttagtgg attaaaatct tctgtattga attatctaaa tgggaaaaga
    36481 atgaagaatg aagaaatagt agttgaagat gtagcagcat cttttcaaga ggctgtggta
    36541 gaggttttat ctactaaggc actaaaagca gtaaaagaaa aaggatacaa tatcataact
    36601 ctttctggtg gagttgcttc taattcgggg cttagagcta aaataacaga gcttgctaaa
    36661 gacagtggta ttactgttaa gtatcctcct ctaattttat gcacagataa tgcagctatg
    36721 atagggtgtg caggatatta taattttata aacgggaaaa cgcatgatat gagtttaaat
    36781 gcagttccaa atttaaagat aaatcagtag agttagataa atttgtaaat ataaaagtat
    36841 tgtttcaaaa aagtaagcag aagtgaaatt aaatataata aaaatcaata tagtatatat
    36901 taaaacttga agtaaaacta tttataatct ttatattcca atgaattgca acacatttta
    36961 ggatatacag gttgtctttg gcttagattt gcttcaagtt taattttttc tatagaaaga
    37021 ttattttaaa aagtgggtaa tatacccttt tttttcattc ttaaaaagtt ttatactaat
    37081 tatagaaaga ttaaggaggg gaagaaatga gtcaaagtaa agaagacaaa ataagaagta
    37141 ttttggaagc aaaaaatatc aaatcaaatt ttcaaaataa agaaaattta agtgaattta
    37201 atgaaaaaaa agcaagtaaa agagcagaag acttattaga tgtatattat aatacattat
    37261 ctactgcaga tatggaattt ccatattggt ataatagaga atatagaaaa tcagatggtg
    37321 atataccagt agttagaaga gctaaagctc ttaaatctgc tttttcacat atgacaccaa
    37381 atataatacc tggtgagaaa atagtaatgc aaaagacacg ccattataga ggttcttttc
    37441 caatgccatg ggtaagtgaa agtttctttg ttgctcaagg agaacaaatg agagaagagg
    37501 caaagaaatt agccagtaac acagctgatg aacttacaaa atttgggtct ggcggaggaa
    37561 atgttactga aagttttgga aatgtcgttt caatagctgg taaattcgga atgagaaaag
    37621 aagaagtacc tgtacttgta aaaatggcaa aagaatgggt tggaaagtct gttgaagatt
    37681 taggttttca ctatgaaaaa atgatgccag attatgattt aaaagaaaac ctaatgagta
    37741 cacttatatg tatgtttgat tcaggatata cacttcctca aggtagagaa gttataaatt
    37801 atttttatcc tttaaattat ggattagatg gaattataga aatggcaaaa gaatgtaaaa
    37861 aggcagttgc aggaaatgca tctggagatg ggcttattgg tatggaccgt ctatattttt
    37921 atgaggctgt tattcaagtt attgaaggat tacaaacttg gattttaaat tatgcaaaac
    37981 atgcaaaata tttagaaagt atagagacag atttagaagc taaaaaagaa tactcagatt
    38041 tagtggagat attagaacat attgcacata aacaacctcg tacatttagg gaagctcttc
    38101 agttgactta tacaattcat atagcatcag taaatgagga tgctatatct ggtatgtcta
    38161 taggccgttt tggtcaaatt ttatatcctt ggtatgaaca agatatagaa aaaggattaa
    38221 ttacaaaaga agaggttatc gaattattag agctttatag aataaaaatc acttgtattg
    38281 actgttttgc ttcagcgggc gtaaatggag gagtactatc aggaaataca tttaatactt
    38341 tatctatagg tggattaaaa gaagatggtt ctacaggagc taatgaacta gaggagttat
    38401 tattagaagc aagtatgaga tgtagaactc ctcaacctag tttaactatg ttatatgatg
    38461 aaaaacttcc agaagatttc ttaatgaaag ctgctgaatg tacaaagctt ggttctggtt
    38521 atccagcctg ggtaaacaac tcaaatggaa caacatttat gatgaaacaa tttgctgatg
    38581 aaggtatgac tgttgaagaa gcgagagcat ttgcattagg aggatgtttg gaaacgtctc
    38641 cagggtgctg gaaacagtta actttaaacg ggaagacata ctctattgca ggtggagcag
    38701 gtcaatctgc tggctctgga gttcacttta tagctaatcc caaaatttta gaacttgttc
    38761 ttatgaatgg taaagaccat cgtatgaata tacaagtatt tgagcctcat aataagccat
    38821 tagatactta tgaagaagtc atagaagtat ttaaagatta ttataaacaa gcaataaatg
    38881 ttttagaaag agcaaataac attgagttag atatatggag aaaatttgat acttctataa
    38941 taaattcact attaaagcca gactgtttag acaaaggtca acatatagga aatatgggat
    39001 atcgttataa tgcaacatta aacgtagaaa cttgtggtac tgttactatg gtcaattcat
    39061 ttgcagcact taagaaactt gtatatgatg acaaagcatt tacaatagag gaaatgaagg
    39121 atgccatatt aaataatttt ggatttaaag atgcattaga agtaggaaat tattctatgg
    39181 cagaccaagt aaaagtagat aagactggta aatatgatgc tatttataag gcctgtcttg
    39241 atgcacctaa atatggaaat aatgatttgt atgcagataa tattcttaaa aactatgagg
    39301 tatggttatc aaaagtatgt gaagaagcac aatctttata tgctaagaag atgtaccctt
    39361 gccaaatatc tgtttctaca catggaccac agggagctgc taccttggct actgcagatg
    39421 gtagactaag tggaacaaca tattcagatg gttcagtctc tgcatatgca ggaacagata
    39481 aaaatggggt atatgcatta tttgaatctg caactatttg ggaccaagca gtagttcaaa
    39541 attctcagat gaatttaaaa cttcatccaa caactataaa agggcaacaa ggaactaaaa
    39601 aattattaga tttaacaaga agttatttaa gaaaaggtgg gttccatatt caatataatg
    39661 ttgtagattc agaaacatta aaagatgcac aaaaaaatcc tgacaattat cgtcaattaa
    39721 tggtacgtgt tgctgggttt actcaatatt ggtgtgaatt aggtaaacca atacaagatg
    39781 aagtaattgc tagaacagag tatgaagggg tgtaaaatat gagaaagcat agtgattgta
    39841 tgaatttttg tgcagtagat gcaaccaaag gaatttgtag attatcaaaa caaatgatta
    39901 atttagatga tgcagcatgt ccagagataa aagtaatgcc aaaatgtaaa aattgtaaaa
    39961 attttgttga agctaatgat gaaggtatag gcaaatgtgt tggcctagag aaagaagact
    40021 gggtatattc aacattgaat gcaattactt gtgaaggaca tgtgtttaat gagtagtcaa
    40081 aagcaattag aaggcatgat tttcgatgta caaagctttt cagttcatga tggtccaggt
    40141 tgtagaacaa ctgtattttt aaatggatgt ccactgagtt gtaaatggtg tgcaaatcca
    40201 gaaagttgga ctgtaagacc acatatgatg tttagtgaat tatcttgtca atatgaaaat
    40261 ggatgtactg tatgtcatgg taagtgtaaa aatggtgcat tgagctttaa tcttgataat
    40321 aagccagtta tagattggaa catctgtaag gactgtgaaa gttttgaatg cgtcaactca
    40381 tgttattata atgcgtttaa attatgtgca aaaccttaca ctgtagatga acttgtgcag
    40441 gtaattaaac gtgattctaa caattggaga agtaatggag gagtaacatt tagtggaggt
    40501 gagccactac ttcagcatga atttttacat gaagtattat taaagtgtca tgaggtaaat
    40561 atacacactg ccattgaaac gagtgcatgt gtatcaaatg aagtttttaa taaaatattt
    40621 aacgatattg attttgcatt tattgatata aagcatatgg atagagaaaa acacaaagaa
    40681 caaacaggtg tgtataatga tttaatatta gaaaatatat caaaccttgc aaattctgat
    40741 tggaatggaa gattagtact tagagtacca gttatctctg ggtttaatga tagtgatgaa
    40801 aatataagtg atattatatc ttttatgcac aaaaataatt tggtagaaat taatctatta
    40861 ccatttcaca gattaggaga atcaaaatgg attcaattag gcaaggaata tgagtattct
    40921 gataagggtg atgttgatga aggtcatctt ggagaattac aagatatatt tttggataat
    40981 ggtatagctt gttatgttgg tcatgagaca gctttctaaa attaaataca agttttaatt
    41041 aaaaaaggat gttacactaa aagctagagt tacatccttt tttatgtggt ttttatgtag
    41101 aaataattaa gtaaagtttt atatatttta tatattgttt atattgcttt atgtccataa
    41161 atattgcttt aaatatactt tatatatttt ttatagttta aattacagtt agagaatata
    41221 ttacgtttac tttattgaag cagaagtttt gtggtaaaat actactatga aaaaatttaa
    41281 tagaatatat tttagaaaca actaaaaata atagttagga ggaagacatc tatatgaaca
    41341 aatcatggag caacttgatt attaagaata aagacaaaaa agtacgttca gggtggatta
    41401 ttatagctgt tatggctacc ttttacatat ttcagtatta tttaagcatg atacttgtgg
    41461 aaataataag aaaaatcctg gttgctacag gggacattaa tttaaaaaca aactattttt
    41521 cagaatatgc taattggtta aatgatgttg ggttacagat tgtatttcaa attctaacag
    41581 attcacttat gattattatt cctataattg tatggagatt tattatgaaa aatcctatta
    41641 gtgaaatggg attacattct tatagaatta agaaaaaaga aggatatgta ggaatgttat
    41701 taggaatatt taattgtaca gtaatcttta ttataacaat aacaattggt ggtggtcatg
    41761 ttacttcatg ggtaccaaaa atttcacctt taacagtttc ttgaatactt gtctttattt
    41821 tagttgcttt tgcagaagaa attttaaatc gtggtttttt tatggcagtt ttacgaagat
    41881 gtaaaaatat ttattttata atgattgttc catctgttat ttttgggttg attcatatat
    41941 ggaatcctga tgttactttt ttgtctgtaa ttaatattat aattattggg attctttttt
    42001 catatatgtt tataaagtcg tcgaatatat ggatgtgtat aggttatcat tttacatgga
    42061 atgtatttca ggggattata tatggtatgc ctgtaagtgg acttcaggtt ccagggatta
    42121 taactacaca aatcactcat ggtaatctat taaatggtgg tatgtttggt attgaaggtg
    42181 gaattttgac tacttttgtt aatctactta gttttatatt tgtatggtat tactatagag
    42241 attctaagta tgattttgtt agtgataaag taaatgtgac caatatcaag aattagttga
    42301 ttataataaa ttttaataat atcttctaag cttaaagtat tctgtaggat tgttggaaat
    42361 ttacaaaaat ataaaaataa cttggatatt ctatttactc caagttattt ttatattctt
    42421 ttgtaaatag aaatggaaca taaaaaatta aaacaaccat agatactatt agtatatcat
    42481 ggtaagtgat agttgattct ttagaatttg tgataagaaa agcactatta tttaaaatat
    42541 gaattatagc acaaaaccag atgttcttag tttttatata aagatatcct aaaaatattg
    42601 aaattccaac tatatgtatc gaacgtaata ttaatcctaa tattggtgtt tcaggtgtat
    42661 ataatgtaaa tattagtggt aagtgccaca aactccaaca aatacctaat attataactc
    42721 ctagtttttt accaaattta ttaaaaaaaa tattctgtaa aaaacctctc caggcatatt
    42781 cttcactaaa aaaaatataa atagtagtta atgatgttat tggagtaaat ataaatttta
    42841 tgataccact ataattaggt tgagaccctt gtagtattaa tataaatgat gttggaacaa
    42901 tta
//
LOCUS       DAJMZY010000023        42436 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.023, whole genome shotgun sequence.
ACCESSION   DAJMZY010000023 DAJMZY010000000
VERSION     DAJMZY010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 42436)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42436)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42436
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.023"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            142..810
                     /locus_tag="OE968_001223"
     CDS             142..810
                     /locus_tag="OE968_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YwaF family protein"
                     /protein_id="HCP7218511.1"
                     /translation="MFKIFLFSSEQFVSLFIFGLFLYYCPKLTKNILPYSYTVEKIIC
                     TLLVIIMALEQLLLISSGNYSTLNSLPIGINYICIYLCIAILIFKQYHLFNIFFSWSL
                     VCSVGELIFSKNLGYEFPSLIYFIFIFSKCLIIYADIYMVDVRKFRVNRYALRDNLAI
                     CFIYFSFIFLLNTFTNSRYYYGFLSHSTTAIFTFIFVTSIMYIPALLFNRDTFILEKK
                     KKSK"
     gene            complement(901..2352)
                     /locus_tag="OE968_001224"
     CDS             complement(901..2352)
                     /locus_tag="OE968_001224"
                     /EC_number="3.4.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucyl aminopeptidase"
                     /protein_id="HCP7218512.1"
                     /translation="MNIKYSKEILKSLENAITVVALFEGEDVSTTFDKINMISRNFNS
                     KENSIDTVTLIENNNLVNVCLVGFGKRELLNREKIRIIGGNLCKKLKNILKNEAYKSS
                     DVNVLNLNLNSDEIGSFVEGILLGNYKFDKYKTKIKDFERKEVDTITIFTEKEVECQI
                     EKAKILANSTIIARNLVNEPSNVIYPKTLAVETVKLGAEFGFNVDVYEEEKIKALGMD
                     AFFAVSRGSINKPRFIVMRYFGDKESTDILGLVGKGLTYDTGGYSLKSNASMLDMKTD
                     MAGAASVIGAMCAISQSKLKKNVIAVVAACENALSGGSYKPGDIISSMAKKTIEVLNT
                     DAEGRLTLADAIYYIINNEKVTKVVDVATLTGAALTLLGNVATPIVTNNDDFYCELEK
                     AATLSGERVWKMPIYDEFKDMIKGEEADLKNTGGKNAGCITAGAFIGEFVGNTPWIHM
                     DIAGTSTSSKSIGYKAKGATGEPVRTLYYLAEI"
     gene            complement(2368..2808)
                     /locus_tag="OE968_001225"
     CDS             complement(2368..2808)
                     /locus_tag="OE968_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HCP7218513.1"
                     /translation="MSDKELSILLLESMNNFHNLIKIINNERYKKDKVLTERQFFALV
                     KIRKHDKIELKNLSRDLHVSTSSLCILLNKLVEQEYVYREEDSRDRRNTFYGITKNGE
                     KILDNEILKFVSIISDKMDCLDIDNKDKLFTSLEESKNIIEQLF"
     gene            complement(3056..3484)
                     /gene="ytfJ"
                     /locus_tag="OE968_001226"
     CDS             complement(3056..3484)
                     /gene="ytfJ"
                     /locus_tag="OE968_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GerW family sporulation protein"
                     /protein_id="HCP7218514.1"
                     /translation="MRATGSIQSLMETTLETIKGSIDANTIIGDPIKTDTTVVVPISK
                     VTIGFGIGGGEYSKGYDDKDREIELKNEKSDTNFAGGSAGAISVQPVAFVVVESGETR
                     IMSLDSNINLVDNILSITPRVLEKIQNISQSNKNQDKNNM"
     gene            complement(3438..4067)
                     /locus_tag="OE968_001227"
     CDS             complement(3438..4067)
                     /locus_tag="OE968_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2953 domain-containing protein"
                     /protein_id="HCP7218515.1"
                     /translation="MELNELFNFKYLIIAVIFIISVTMLILISHINILIIADIKNKDI
                     CLKLNIKYMFNLININRQLYPAENSKNNDKKEGMKNNIDSSILLADDLLSIYRLLKKI
                     KIHELYSNINFGTGNIGLTSSVYVLINTLYGNLFNMIDAEKMYLNVNPDFTKDYVLGN
                     IRIHIRPRIKALFNIIIMINKIMNKNKGNKEGDSNESNRFDTESYGNNS"
     gene            complement(4229..4768)
                     /gene="scpB"
                     /locus_tag="OE968_001228"
     CDS             complement(4229..4768)
                     /gene="scpB"
                     /locus_tag="OE968_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HCP7218516.1"
                     /translation="MKREDIKYIIESVMFAYGEPISIKELNYIINKELSSKEIEIMLN
                     LLIEEYREQNRGIQIIKLENKYQMCTNKDYAEYIKKIIEPKKKKSLSQATLETLTIIA
                     YKQPITKVEIEDIRGVKCDKVLQTLFENELIREAGRLNKIGKPIIYKTTDEFLKLLNI
                     ESLEELPPIENYQEVATNE"
     gene            complement(4770..5489)
                     /locus_tag="OE968_001229"
     CDS             complement(4770..5489)
                     /locus_tag="OE968_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HCP7218517.1"
                     /translation="MKYNIQLQVYEGPLDLLYDLITKHKIDIKDISIIDITKQYLNYL
                     KMLDKMDLEITSEFITMASKLLEIKSKYLLYKQKDEEEDPRIELMEKLEEYRKFKVAS
                     QDIKENITYVNERFYRNKEEIIIDDNVDLEDISIEAIKNILPYIFKVKTSQIENANDE
                     KLDKIVRKKIISVEEKILYIRDIIKEKIEVTFTNIIKSYENDEIIATFLSILELIKEK
                     EIVVVQDIFFDDILIRKSSEC"
     gene            complement(5519..6115)
                     /locus_tag="OE968_001230"
     CDS             complement(5519..6115)
                     /locus_tag="OE968_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HCP7218518.1"
                     /translation="MLSMNIGEIVASLVGIAMAISIHEFGHAYSAHLLGDDTAKAYGR
                     MTLNPVRHVDPIGLLAMFILKIGWAKPVPVNPNNFKNYKIGNLIVSLAGVFCNVLTAI
                     LCVIINKYVHMYAINTIAEYVFLYSIGFAAFNLLPIPPLDGWGVISTFVPYKWNEYLY
                     KFESMSYIILLIALFTGMYRIILTPIYAVLLKIVYLFV"
     gene            6413..7249
                     /locus_tag="OE968_001231"
     CDS             6413..7249
                     /locus_tag="OE968_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HCP7218519.1"
                     /translation="MRQEERTVCFDRELKIEAYRFKGIMQKFPNHFHEHYVIGFIEKG
                     QRYLSCKNKEYTTSTGDLLLFNPFDSHTCEQIDDKVLDYRCINIKPEIMKKTVFEITG
                     KNYLPKFNQPVIFRSELVPLLQELHYIIMEEELDFKKEELFFFLIEQLIEEHTEPNLQ
                     SNLENTNIEIQAVCDYLENNYAEHIILDELSTIAGMNKYSLLRNFTKLKGITPYRYLE
                     NIRVNKAKKLLEKGVEPIDAAIQTGFVDQSHFTNFFKNFIGLTPKQYQNIFINDDSNN
                     FK"
     gene            7270..7692
                     /locus_tag="OE968_001232"
     CDS             7270..7692
                     /locus_tag="OE968_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2000 domain-containing protein"
                     /protein_id="HCP7218520.1"
                     /translation="MENKNSKCVMVIDENLPMGIISNTAAIMGITLGKHAPETVGPDV
                     IDKTGNSHLGIIDIPVPILKGNKEIIKDLRKKLYTLEFNDLTVVDFSDVAQSCNLYEE
                     FTQKIASVPEDELQYFGIAIYGNKKKVNKLTGSMPLLR"
     gene            complement(7903..9066)
                     /locus_tag="OE968_001233"
     CDS             complement(7903..9066)
                     /locus_tag="OE968_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HCP7218521.1"
                     /translation="MKKLASTALAILIALTPLSFSFANNKENADANQLNISSKSAILM
                     DVGSGQILYEKDAHKKLPPASVTKVMTMLLIVEALDSGKIKLDDEVQVSETASSMGGS
                     QIFLEPGETQKVDTLLKGIAVASANDACVAMAEHLAGSVEGFVDRMNAKAKELNMNDT
                     HFANTNGLPVANHYTSAHDIALMSRELLKHEMISKYLTTWMDKVVVGKKQVTVGLANT
                     NKLIKHYQGATGVKTGFTQEAKYCLSASAKRGNTHLVAATLGAETSPERFNDASSLLT
                     YGFANYESVKLCSKGDNIATLTLDKADENKVKLVAKEDLNALIKKGSSKEFEKKIEIV
                     KNPKMPIKKGTVLGKIKICKDKKVIGEVELINTKDINKASYLQMLQRIIDNMI"
     gene            complement(9120..9320)
                     /locus_tag="OE968_001234"
     CDS             complement(9120..9320)
                     /locus_tag="OE968_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore protein"
                     /protein_id="HCP7218522.1"
                     /translation="MDDVSRQNAIKALKQTKMEIAGEYGMNYEDAFEIIENASNKGVL
                     EGYFKKLEKKKNLGQGISRHLE"
     gene            complement(9528..11204)
                     /locus_tag="OE968_001235"
     CDS             complement(9528..11204)
                     /locus_tag="OE968_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HCP7218523.1"
                     /translation="MQLFKKNTNKIKVMALGGLNEVGKNMTVVEYKDEIIVIDAGLSF
                     PEDEMLGVDIVIPDITYLVKNRDKIKGIFITHGHEDHIGALPYILKKINVPVYGARLS
                     IGLIQVKLKEHKMNNVKLNVIGPRQVIKLDNMEVEFLKNNHSIPDAYSIAIHTDQGII
                     YHTGDFKIDLTPIDGDVMDMHRICELSKKGVLLMLADSTNAEKPGFTMSEKTVGVGLD
                     ELFAKGNGRRIIVATFASNIHRLQQIINTAEKFNRKVAISGRSMVNVVGVAKELGYLD
                     ISDDMLIDLNDICKYEDSELVIITTGSQGEPMSALARMAFSEHKKVEIKSGDLVIISA
                     HPIPGNEKLISRVINFLFEKGAEVVYSDIADIHVSGHACQEELKLIHALVRPKFFMPA
                     HGEYRMLKRHAEIAEQLGMDKENIFVMQTGDVLELDKNSAKVANRIQTGNILVDGLGV
                     GDVGNIVLRDRKHLSEDGLMIVVVTISKDEGKVLAGPDIISRGFVYVRESEDLMDGAK
                     DIIKNVLNECEEKNIKEWAYLKNNIKENLKEYLYQKTKRNPMILPIIMEV"
     gene            11421..12158
                     /locus_tag="OE968_001236"
     CDS             11421..12158
                     /locus_tag="OE968_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HCP7218524.1"
                     /translation="MRGKTHCAIGILTAIQTSLIFKIPISLVDILVSATFAVLPDLDK
                     SNSMVSNFILKNNVSKYIYRIFIYAVNIIIFFISININDNFYLSAIITFVAIIIIEAK
                     LTHTFLRKVFLSLIFILLAICLYIIEVEIYFTIFCLMLSIFPWLKHRSFSHSIFATII
                     VYFLLKQIELITNINNLSFYGTIGYASHMFLGDLFTKQGIPIFYPLSEKKISLGFLTV
                     GGPFSNFIEKSFIFVLIGLIIFSILKL"
     gene            complement(12275..12733)
                     /locus_tag="OE968_001237"
     CDS             complement(12275..12733)
                     /locus_tag="OE968_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HCP7218525.1"
                     /translation="MANTMDLLKDKLKETGFKITPQRRAIVEILLKHDHSHLSSEEIY
                     DLVRVDCPEIGLATVYRTMQLLDEIGLISKLNLDDGCIRYEISLHKEDCHNHHHLICK
                     NCGKIMEAKEDLLDNIEKEIQSLYKFKILDHDVKFYGLCDECNGVSDSEE"
     gene            complement(13015..13302)
                     /locus_tag="OE968_001238"
     CDS             complement(13015..13302)
                     /locus_tag="OE968_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HCP7218526.1"
                     /translation="MEENIINLIDENGVESQFEIILTLEAEGKEYAILMPLDDEEAEE
                     ALIFRIDEDEEGEILIPLESDEEYETVVAVYTAIMEEEGLNYDEDESNGLN"
     gene            complement(13380..13805)
                     /gene="ruvX"
                     /locus_tag="OE968_001239"
     CDS             complement(13380..13805)
                     /gene="ruvX"
                     /locus_tag="OE968_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HCP7218527.1"
                     /translation="MLDGRIMGLDVGDKTIGVAVSDLMGLTAQGVKTIKRVGKKKDIE
                     ELKAIIKEKQVNKIVSGLPKNMNGTLGPQGEKVIKFCELVKAETGIDVEFWDERLSTV
                     AAERSLLEADVSRQKRKKVIDMLAAVIILQGYLDFKINS"
     gene            complement(14011..16182)
                     /locus_tag="OE968_001240"
     CDS             complement(14011..16182)
                     /locus_tag="OE968_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218528.1"
                     /translation="MRKKIMSLFAIVIMIFVSTASYGFAEEKGKVIFIDMNRTNLGSM
                     MNIPILKNEIEKRGYVALMNIRGDQGTDDRRSCASMGAGTRASVTTEDYINFQKVDQD
                     TAKAFEVATGQKAKEINDLGINRSINENLEYGEYGANLGSLGKTLSENGLKTSVIGNA
                     DIIENNQLVKNRNLCLVAMDQYGRIDSGNIDNINKKDSKMPFGISTDYDKLLDETKKS
                     YKNSDAIFVELGDTYRLDMYRLNLNDNTYDTMKKNIVKNINKYLEQVFSMVGENDTVY
                     IASAFPSDLDYKNKRRLSPIIKFSGEGKGLLESATTRKAGIVANLDVGVDILGTFGLE
                     NKEMVGRSYTLVNKEDNISYLKSLYERIVSISSIRSTIINGFVGVISASWVIAMFAIF
                     FRNYMPHKERVFKVLKEFIKLGIIMPLSFMLAPLMNFKTPISISLGIFATTLILYLLG
                     RKLFKDNDIKHMGFFATLTILVIVIDSVFGTYLMQNNIMSYDAVIGARYYGVGNEYEG
                     VTIASAVFGLAVLLHYKKVSKLLVVIFSLIILITSAYPSMGANVGGAISECVAYLLFI
                     MLIYDIKIDFKKAVLLAVSAVVVVFAFAALDILSGSESHLGMFVQRIFLNGPGEILQT
                     FGRKIQMNMQLAQTSVWVNILLVGIGVIAVLIFKPSRHFRKIMNNFPILFKGFIASMV
                     GCIITLLVNDSGIVAASTASIYILIPLIIISINMIIFEKNN"
     gene            complement(16192..16449)
                     /locus_tag="OE968_001241"
     CDS             complement(16192..16449)
                     /locus_tag="OE968_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HCP7218529.1"
                     /translation="MEKDLDYTMKFEGIPEDRMSVGDTIDFVYKALVEKGYNPINQII
                     GYLLSGDSSYITSHKNARAIIKKFERDEILEEVITHYLNRK"
     gene            complement(16474..19113)
                     /gene="alaS"
                     /locus_tag="OE968_001242"
     CDS             complement(16474..19113)
                     /gene="alaS"
                     /locus_tag="OE968_001242"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HCP7218530.1"
                     /translation="MEKMGLNEIRSKFLEFFESKGHYVANSYSLVPNNDKSLLLINSG
                     MAPLKNYFSGVEVPPSVRMCTSQKCIRTGDIENVGITARHATFFEMMGNFSFGDYFKR
                     ESIKWGWEFVTEWLNIPEDKIWVTVYEEDDDSYDIWAKEMNFPEERMVRLGKDDNFWE
                     IGTGPCGPCSEIYFDRGEEYGCDNPDCKPGCDCDRYLEFWNHVFTQFDRDEEGNYSLL
                     ENKNIDTGMGLERMGCIMQGVDTIFEVDTIKSILEAVEKLTGVKYGENPKNDISIRII
                     TDHIRAVTFLVSDGVLPSNEGRGYVLRRLLRRAARHGKLLGVKELFLQKLIDEVIKVN
                     DKAYPVLVEKESYIKKVVGIEEEKFNETIDQGTEILNSYIEVLKNEGKTVLSGQEAFK
                     LYDTYGFPIDLTKEILEEEHLSVDEEAFNEEMEKQKERARNARGNMDGESWKEDPLSK
                     LESTVDSTFNGYSEIYGEGTIEAIVKDDELVQSAEEGDKVSIVLDNTTFYPEGGGQVG
                     DCGLITNENLVLEVLNTKKGANNSIKHIGIIKSGRISNGDKVKTLVDRETRMSAARNH
                     SATHLLHKALREVLGEHVNQAGSLVTPERLRFDITHFEAISNEELKVIEEKVNNVILS
                     SLDIKCDIMNIKEAKEKGATALFGEKYGDEVRVVSMGDYSTELCGGTHLTNTSQVGMF
                     KILSEGGVAAGVRRIEAITGKAVYEYLKERDGIISEVCVNLKSKEDNLIQRISSLLEE
                     NKNLSKELHDMKAKMSLQSVDSIFDSKVEVNGVNLITNKFEGMDMDTLRETADNLRDK
                     LGSGVVVLANVVDDKVNFVVTATKDVLDKGIHSGNIVREVAKIAGGKGGGRPNMAQAG
                     ASDVSKVDQALSYASEVIKTQVK"
     misc_binding    complement(19181..19419)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(19562..20641)
                     /gene="mnmA"
                     /locus_tag="OE968_001243"
     CDS             complement(19562..20641)
                     /gene="mnmA"
                     /locus_tag="OE968_001243"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HCP7218531.1"
                     /translation="MNKKVMIGMSGGVDSSVAAYLLKQQGYDVIGVTMKLWQDDDVVE
                     IEGGCCSLSAVEDARRVANKIGIPFYVLNFREVFKEKVIDYFIDEYLEGKTPNPCIAC
                     NKHIKFDDFYKKARQIGCDYVATGHYAKIEKDESTGRYLLKKSVTDKKDQTYALYNLT
                     QEQLEHTLLPIGDYEKDRVREIAKEMGMAVHNKPDSQEICFVKDNDYANYVKKHSKKR
                     IEEGFFVDTKGNILGKHKGILYYTIGQRKGLGITFGKPMFVIDINPINNTIVLGDNED
                     LFKKELIAKDVNFISIDTLEEPLRVQAKIRYSAKPSPATIHRVGEDTIKIVFDEAQRA
                     ITKGQSVVMYDGDIVVGGGIIEKSL"
     gene            complement(20930..21370)
                     /gene="nifU"
                     /locus_tag="OE968_001244"
     CDS             complement(20930..21370)
                     /gene="nifU"
                     /locus_tag="OE968_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly scaffold protein NifU"
                     /protein_id="HCP7218532.1"
                     /translation="MQYSDKVMEHFMNPRNMGEIDNASGVGEVGNPTCGDIMKIFLDI
                     DGDVIKDVKFKTFGCGSAIASSSMATEMIKGKTIKDALELTNKAVAEALDGLPPVKMH
                     CSVLAEQAVKAALIDYAQKNNIHIPELDGYVIDDAHDHDVEEEE"
     gene            complement(21424..22617)
                     /gene="nifS"
                     /locus_tag="OE968_001245"
     CDS             complement(21424..22617)
                     /gene="nifS"
                     /locus_tag="OE968_001245"
                     /EC_number="2.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase NifS"
                     /protein_id="HCP7218533.1"
                     /translation="MEKRRLYMDYSATTPIKKEVLDAMMPYLTDYFGNASSFHTFGRE
                     AKDALDKAREQVAALINAEPSEIYFTAGGSESDNWTLEGVAYANKNKGNHIITSKIEH
                     HAILHTCEYLAKHHGFEITYLDVDSEGKVDLKQLEDSIKDTTILISIMFANNEIGTIQ
                     PIKEISEIAKKHKILFHTDAVQATGNIPVDVKELGIDLMSMSSHKIYGPKGVGALYIR
                     KGVRLHNFVHGGAQEKSKRAGTENIPAIVGYGKAAELAKENMQNHVETLTRLRNKLID
                     GVLERIPYTRVNGSLDNRLPGNANFAFQFIEGEGILLLLDMLGIAGSSGSACTSGSLD
                     PSHVLLAIGLPHEIAHGSLRLTVGDFTTDDDIDYILENLPKVIERLRSMSPLYDDAKK
                     QGLVK"
     gene            complement(22635..23081)
                     /locus_tag="OE968_001246"
     CDS             complement(22635..23081)
                     /locus_tag="OE968_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HCP7218534.1"
                     /translation="MKLSTKGRYGLKAMFELALNQDNGPVSLKFIAKKQKISDQYLEQ
                     IFSSLKKSGLVKSVRGAQGGYLLSKNAEDITVGDILVVLEGPVALSDCVLDEDVCENS
                     NMCVTKIVWEKMKKGIEDVIDSITLKDMINDYNKNKLENDITNIKK"
     gene            complement(23190..23960)
                     /locus_tag="OE968_001247"
     CDS             complement(23190..23960)
                     /locus_tag="OE968_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCP7218535.1"
                     /translation="MIIKLNSTYHSRVMKYLKKEPEYNLFIIGDIERYGYGNNFLNIW
                     ADVGEHGEIKAILLKYFEFMIFYSDGEYDVEGFYNLLRNTNYEEISGKICAVDALAKR
                     LGLNNLKVVDFCKLQTKKFLIDNNCNAKVKRIRLGNLKKTVKLYDLIDEFHSTTLENL
                     KNGLRTGRGYCIEINKQVVSMAKSTSENRTHAMIIGVGTHPKYRAKGLATKCLIKLCS
                     ELLRENKIPCLFYDNEEAGKIYKKLGFENIGKWGIYSK"
     gene            complement(23991..25256)
                     /locus_tag="OE968_001248"
     CDS             complement(23991..25256)
                     /locus_tag="OE968_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HCP7218536.1"
                     /translation="MPLADKIRPKTMNDVIGQSHIIGNGKILSKILQSNFLPNMIFFG
                     PPGVGKTTVAEIIAERSNKSFYKINATNSSLEDIKKVISELGSINNVNGVLLYIDEIQ
                     SFNKKQQQSILEFMENGSITLIASTTENPYHYVYKALLSRSTVFEFKPLEKLDVEKGL
                     KRAVEVLNEDSYMDIECNNNAIEDIAILSDGDMRRALNILEVVVYSTKPNKDNITYID
                     SDVIRASTFNKIINYDKNGDSHYDILSAFQKSIRGSDPQASIHYLARLIKGGDLISIC
                     RRLLVIASEDIGLAYPNAIVIVKACVDSAMQLGFPEAKIPLAEATILLATSPKSNSAC
                     IAIMKAMDELDKEFVKDIPNSIKDSHYSGSKEIGRGCGYKYPHNFKNHYVKQQYLPDS
                     IKDSIYYIPQENKTEKNIKKYLEYLNSDF"
     gene            complement(25363..26148)
                     /gene="codY"
                     /locus_tag="OE968_001249"
     CDS             complement(25363..26148)
                     /gene="codY"
                     /locus_tag="OE968_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HCP7218537.1"
                     /translation="MASEVLQKTRKINKTLQTSGGSSVSFDLLAGALGDVLSSNVYVV
                     SAKGKVLGLHLNDVQDSSVIEDEYTKQKKFSDEYTQNVLKIDETLENLNGEKILEIFP
                     EEHGRLQKYTTVVPILGSGQRLGTLVLSRYSNSFNDDDLVIAEYSATVVGLEILRAIG
                     EELEEEMRKKAVVQMAIGTLSYSELEAVEHIFAELDGKEGLLVASKIADRVGITRSVI
                     VNALRKFESAGVIESRSLGMKGTHIRILNDKLTDELKKLKNNQ"
     gene            complement(26313..28400)
                     /gene="topA"
                     /locus_tag="OE968_001250"
     CDS             complement(26313..28400)
                     /gene="topA"
                     /locus_tag="OE968_001250"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HCP7218538.1"
                     /translation="MAKTLVIVESPAKAKTIEKFLGKSHYTVKASVGHVRDLPKSKLG
                     VDIENNFEPQYINIRGKGDVIKELKKEAKKSKQVYLATDPDREGEAISWHLAHILNLD
                     ESEDCRIEFNEITKDAIKKAIKHPRNIDINLVDAQQARRVLDRLLGYQISPILWQKVR
                     KGLSAGRVQSVTTKLICDREKEIKAFIPKEYWTIDVEAKTVKDKDITLKFYGKNDEKI
                     ELENEEAVNEILKEMEGKDLKVEKIESKSRRKSAPKPFTTSMLQQEGANKLFFTTKKT
                     MMIAQELYEGIDIEGEGTVGLISYIRTDSKRISDEAKEKAKGYIVNNLGENYYKNTGD
                     KKEKKDTKKVQDAHEAIRPTSVDRTPESIKASLSKDQYKLYNLIWRRFVASQMEDSVF
                     DILNVECKIGDIVFKATGSKMKFDGYTKVYNFSEREDKILPSIEKGDILNIENILPDQ
                     HFTQPPARYTEASLVKTLEELGIGRPSTYAPTIATILNREYVEKQGTSLCPTELGIIV
                     TDILENNFHKFIDVDFTADMESKLDVIEEGNTDWKKIVSESYAPLKEAIEEALENIEK
                     VNMDEETDEICENCGSNMVIKYGRFGKFMACKNYPDCKTTRPIMNKIGVKCPKCEEGD
                     IILRKSKRGKAFYGCSNYPNCDFVAWNKPTGEFCEKCGSYMVEKVTKSETKTVCSNKE
                     CNKETKEHNDGKE"
     gene            complement(28433..29533)
                     /gene="dprA"
                     /locus_tag="OE968_001251"
     CDS             complement(28433..29533)
                     /gene="dprA"
                     /locus_tag="OE968_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HCP7218539.1"
                     /translation="MEKRDTYLWLKSIGGITTKTIEIIENEIVNIEDIFDFSEKEIYN
                     LKNISLNIRKNIVKYRGHAYLENIKELLYKKAIKYICKYDKEYPENLKNIYNAPKLLF
                     YKGDIGLVNNNFNIAIVGSRKPTAYGINCAKTISCQLSQYGVNIVSGLAIGIDAYSHI
                     GCMSGKSKTIAVLGSGVDNPLPKQNLHLSNKILENGGLLLSEYNINSTVAPYHFSNRN
                     RIISGLSDGVVVVEAAIKSGALITVDFALEHGKNVFAIPGNINSQMSRGCHKIIKEGA
                     KLIENIDDILNEYNIFNIIDKKINQKYDNISLNAKSKQIIEAIKREGNLHIDSICDYT
                     GIEIKYVNSIINELVLNELVVEMNNKTYSLNV"
     gene            complement(29552..31153)
                     /locus_tag="OE968_001252"
     CDS             complement(29552..31153)
                     /locus_tag="OE968_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YifB family Mg chelatase-like AAA ATPase"
                     /protein_id="HCP7218540.1"
                     /translation="MLSIINSSNLVGIDSFLVKVEVDVSNGIPSFNIVGLPGKEIKEA
                     RERVKSAILNSGYKFPSTRIVVNLSPADIKKEGAFLDLSISIGLLRELIKKDENYIRE
                     SMFIGELSLDGKIRKVRGILPIIMGAKTQNIKRIFIPIENIKESLFVDEIDIIPIKSL
                     KECVDFLNEEIKVDKVRIMSFLDDKSRKENEELEKDNSYIDCKYTKINNEESKYDEDF
                     KDVKGNYFVKRSAEIAAAGNHNMFMIGPPGSGKTMIAKRVRTILPDISVEEMIEVSKV
                     YSILGMINETKGIIDKRPFRAPHHTTTKQSLIGGGMDARPGEIALAHRGILFLDEIAE
                     FDRKILETLRQPIEDGYVNISRVKYSAKYPCRVLLVAAMNPCPCGYYMSETECRCRSN
                     EIDRYINKISGPLLDRFDIFVEVNSIKYSDFNSLKQEESSQKIKRRVENARKIQINRF
                     KKDNIKNNSEIKAYNLFKYCKLEKEASKTAEMIFNKYNLSSRSYTKLLKMARTIADLE
                     ERDLINSQCIIEAFSFRKAYYSYFK"
     gene            complement(31184..31528)
                     /locus_tag="OE968_001253"
     CDS             complement(31184..31528)
                     /locus_tag="OE968_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YraN family protein"
                     /protein_id="HCP7218541.1"
                     /translation="MNNKEKGDFGEKVAVNYLLSKGAKILEKNYRLKIGEIDIIAKME
                     DEIIFVEVKSRSNIKFGYPCESVSFKKRKKIIGVANYYIIKNNLNNTPVRFDVIEVYL
                     LEKRINHIMNAF"
     gene            31712..32875
                     /locus_tag="OE968_001254"
     CDS             31712..32875
                     /locus_tag="OE968_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HCP7218542.1"
                     /translation="MNREKLVAFIRYLSLFILVVSYLKNVENTLYPVITMIILFLIII
                     NNQVRFFSLSNENKFILISYFLELILIFILCNYTKTFNSIYFVPLILDISFLIKEKYK
                     YILFSFVIISSLIISLDKNIYLALESSSILLIITVLSIYIENENLSKLYSQNLYDKLR
                     ISKDELKKVNADLETYASSIEELAILKERNRISREIHDSVGHSLSTTIIQLNAIEKLL
                     KDKPLIYDLVHELREFVTESFQDVRRAISELKPVEYENYQSLFKIKELVKSFIKLTNI
                     NVKLTISKNTWNLSRNQSITLYRLIQESLSNSSRHGKATEIRIFITFNTSNLIITISD
                     NGIGCGNIKKGNGLNSINERIYELNGKVEFDNSNNGFTIRASFPKFSGGDFFE"
     gene            32868..33515
                     /locus_tag="OE968_001255"
     CDS             32868..33515
                     /locus_tag="OE968_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCP7218543.1"
                     /translation="MNKIKVLIVDDEKLIRKGLKIILSSYNDLEIVGDASNGYEALEF
                     CKMNDVDIVLMDIRMKVCDGVLGTRLIKEYNNSITLLILTTFNDDEYIKDAMKFGASG
                     YLLKDSSDEVLHEGIRSSFFGNIVLDKSVAEKIMTSEKTVKQEHLYDMYNLTEKEISI
                     IRLIANGLNNKEISQELFLSEGTIKNNITNILAKLELRDRTQLAIFAFKNKIVIE"
     gene            33644..34579
                     /locus_tag="OE968_001256"
     CDS             33644..34579
                     /locus_tag="OE968_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCP7218544.1"
                     /translation="MDIVRVNNITKRFNDKLVLDNISFSVKKGEIFGLIGPNGAGKST
                     LINIITNLMLPNSGSIQINGLDLSKDYIKAKSIIGLVPQELAIIETLTPFDNLEYFGA
                     FYGLKGKLLKERIIEALEVTGLTEVKKKKVKKLSGGMQRRLNIGIALLNHPKILILDE
                     PTVGVDPQSRNHIFNFIKDISKKHETTVIYTSHYMEEVEHLCSKIFIMDEGKEIAFGD
                     NDYLKSLVSTNTKLIIEIKNINAQLIFDLKNTKGVISVLENNSLLELDIDKKLQLTDI
                     LSVIDKNNSKIMKISYEEPSLEDVFLNLTGKNLRD"
     gene            34593..35690
                     /locus_tag="OE968_001257"
     CDS             34593..35690
                     /locus_tag="OE968_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCP7218545.1"
                     /translation="MKLYMSVKTMLKSLKSSFILNLIYFLALPLILSWFLGMVTESMF
                     QNPIKTESTPIVIYDKDNTRLSNDLTKYLKNDLSYILTVKKDDSKAELKLTIPKGYES
                     SLLNEKSNTLNIEKLGTRDDIAILLQDILDTYHEKFYLNNSQKISSEDFSKLFNKNSI
                     DTSIINNNVKQNSYEYFALVSLGFLVIIFIMNNILSNYISESKGLSKRLYSMPITRVQ
                     FLIYDFVGLWIYSFIFLLLYVLFFRILGITFKGNFAILLLLCALSSYFMTSISTFVTS
                     FFSKKYGTAIVYALLFLQTIFGGIFSMISDTFTKLTSLSPTYLIGELFSNYETFKTID
                     SIGDLIFTCLIISTILIALAIVKEKYKWREV"
     gene            35693..36757
                     /locus_tag="OE968_001258"
     CDS             35693..36757
                     /locus_tag="OE968_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCP7218546.1"
                     /translation="MIRLTIANIKRYLKNHNLLINMVMLPIILIFSLNFFINNSGNQS
                     MYFSPVAIVSDSSGKYEHKLINSSKLKENSFRLNELDKAMNLLKNNKVSAVFVLDKNF
                     SNSIDKLQRPVVKCFKIENGGGSLWAESQIESFITKSLKLKVDKNIDDKLTKTNIIDN
                     KPDKNKGSFLVVFLICYFMYINAAHLASDLFTLKKSNVLKRLISTDNKDIKIIFSIFL
                     GLFFIQSIVYTFALLCFSIIEDFNLSLNVLMIVLANSFVSTGFVFWVARVFKNESSIS
                     LISTFYSLIGLAISISSLIPSMDKLSFMTNLSKFTPFYWTIDAIKNNGSILINIIALI
                     LIGIIFVTAGSLKLRDFAKN"
     gene            37001..37498
                     /locus_tag="OE968_001259"
     CDS             37001..37498
                     /locus_tag="OE968_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CarD family transcriptional regulator"
                     /protein_id="HCP7218547.1"
                     /translation="MYKIGESVMYPKEGACSVNDIVTKKINHEMQKYYELSVIFNSNL
                     KISIPVLNADRIGIRPVMDGNDVDNFIQSINKTDGVWIFDRKERLKLYQDKFHSGDVF
                     EIVKLIKMLMIQDSSKQLCSTDKEFLNKAQKFALSELAAAQCKSYTMVLEEMKKHILN
                     SKNTN"
     gene            complement(37674..37922)
                     /locus_tag="OE968_001260"
     CDS             complement(37674..37922)
                     /locus_tag="OE968_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218548.1"
                     /translation="MSRKAYEEALVELEKFIDERKEIIKSAEDCIDKYIVDRTLPFDY
                     KDKCVEWQQELLDIAEAQVLEANELSVLLQEKKELEED"
     gene            complement(37988..39004)
                     /locus_tag="OE968_001261"
     CDS             complement(37988..39004)
                     /locus_tag="OE968_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HCP7218549.1"
                     /translation="MEYNELLKSARENLNGSCKVCKVCNGVACAGEVPGMGGKGSGSS
                     FIENSKSLEKVKVNMRVIHDVSNPDTSIEMFGKKMSAPIFAAPVTGTTLNMGGKINER
                     DYIEPVVAGCANSGIYAMVGDTAVDAFLMENLDVVKKYNGAGIVFIKPWDNENIIKKI
                     RLAEEAGAFAVGVDIDACGLVTLSLHGKPVLPKNVKQIKELVKSTKLPFILKGIMTVE
                     DALMAVEAGVDAIVVSNHGGRVLDCTPGACEVLPKIADAVKGKVTILADGGVRTGLDV
                     LKMIGLGADAVLIGRPFVTASFGGATDGVETYVNKLQSELSSSMILTGCQTIKDIDGK
                     VIYK"
     gene            complement(39062..39829)
                     /locus_tag="OE968_001262"
     CDS             complement(39062..39829)
                     /locus_tag="OE968_001262"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HCP7218550.1"
                     /translation="MQDKSVREIKEIIETLEVEKYMEYIELLRVDERKSVQGLAIKLA
                     KKLDNIRKEEERLETINIFENEGYDKGYLYIGGIDEAGRGPLAGPVVASVVVFKKDTK
                     IEGVNDSKKLSEAKRDELFEVIKEEALDYGIGIVNNEEIDEFNILNATYMAMKKAINC
                     LKKAPDYLLVDAATIPGIDISQNPIVKGDSKSISIAAASILAKVTRDSIMYQYDRVYP
                     EYGFKSHKGYGTKEHYEAIEKYGITPIHRKSFLKNIL"
     gene            complement(39897..42086)
                     /locus_tag="OE968_001263"
     CDS             complement(39897..42086)
                     /locus_tag="OE968_001263"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobalamin-dependent
                     ribonucleoside-diphosphate reductase"
                     /protein_id="HCP7218551.1"
                     /translation="MKYIIKRDGTKELFSKSKIEDAVYKASINSEGGVDRELAYDISR
                     KIANDYNSMEKCLSVEEIQDIVEVLLMESNRKDIAKHYILYRERRSEIRTKAWEFDEL
                     QKSIWKNKYRHNGESFDEWIKRISNNSSRISKLIRQKRFLFAGRILANRGLQKEGKKV
                     TYSNCYVIEPPKDSIEDIFDTAKKLARTFSYGGGVGIDISKLRPKGAKVNNAAKHTTG
                     AVSFMELYSMTTGLIGQRGRRGALMISMDVNHPEIEDFIDIKTDLEKVTKANISVRVT
                     DEFMQAVREKKLYNCTFEVETTGEKIVKIVNAYDLFNKFVKNNWDYAEPGILFWDKIK
                     TYNFMSEDKNFCFSGVNPCAEEPLPSGGSCLLGSINLSEFIIQPFGEHATFDINKLKS
                     CVREAVVALNDVLDEGLNLHPLQEQRDSVHKYRQIGLGVMGIADMLIKMGIRYGSDES
                     LELCDLIGKTMLNEAVKQSALIAKEYGTFSEYKYENISKSKFFIENLNEDTKEMVKKY
                     GLRNSQLLTIPPTGSISTMIGISGGIEPIFNLSYIRKTESLHDEDVYYKVYTPIVKEY
                     MDKKGITDEECLPDFFVTAMNIGYEERINMQKVWQKYIDASISSTINIPFETTVEDVF
                     NIYIKAWEAGLKGVTIFRDGCKRSGILINEKKEENNKEDKKENSKKEYYKNNKKEKDN
                     KDEKAKEIINKNFEEDEKFVCPECGSEGIAHTGGCSICLKCGYSGCN"
BASE COUNT        13635 a         7289 c         4471 g        17041 t
ORIGIN      
        1 ctacaaaaca ataggatatt ttacctatta aaattcatat aaaaaatcta actattatta
       61 tcttttttat atattaaatt gagatataat gaatatattt atatagatac atattaaatt
      121 tattatagga gagaatgtta tatgtttaaa atttttcttt tttctagtga acaatttgta
      181 agtctcttta tatttggatt atttttatac tattgtccaa aactaaccaa aaatatttta
      241 ccttatagct atacagttga gaagataatt tgtacattac ttgtaataat tatggctcta
      301 gagcaattat tacttatttc ttcaggtaat tatagtactc taaactcttt accaattgga
      361 atcaattata tttgtatata tctgtgtata gccatactaa tttttaagca gtatcatctt
      421 tttaatatat ttttttcttg gagtttagtt tgttcagttg gagaactcat tttttctaaa
      481 aacttgggct atgaatttcc tagcttaata tattttatct ttatcttctc taagtgcttg
      541 ataatttatg cagatatata tatggttgat gttagaaaat ttagagttaa cagatatgca
      601 cttagagata acttagctat atgttttatt tatttttcat tcatattttt actaaacaca
      661 ttcaccaact ctaggtacta ttatggtttt ttaagtcata gcacaactgc tatttttacg
      721 tttatttttg ttactagtat tatgtacata cctgctcttt tatttaatag agatactttt
      781 atacttgaaa aaaagaaaaa gagtaaataa tttatttaaa taaaaaataa agccacatag
      841 ataatcttaa attacaaaaa tatccacgtg gctttataaa ttatatttta taattgtttt
      901 ttagatttct gccaaatagt acaatgttct aacaggttct cctgtagccc cctttgcttt
      961 gtatccaatt gattttgatg atgtacttgt ccccgctata tccatatgta tccaaggagt
     1021 attcccaaca aattcaccaa taaaagctcc tgctgttata catccagcat ttttaccacc
     1081 agtgttttta aggtctgctt cttctccttt tatcatatct ttaaattcat cataaattgg
     1141 catcttccat accctttccc ctgataaagt ggcagctttt tctaattcac aataaaaatc
     1201 atcattattt gttactatag gagttgcaac attacctaac aatgttaaag cagcaccagt
     1261 taatgtagct acatcaacca cctttgttac tttttcattg tttataatgt agtatattgc
     1321 atcagctaat gtaagtctac cttctgcatc cgtatttaaa acttcaatag ttttctttgc
     1381 catagaacta attatatctc caggtttgta tgaacctcct gataaagcat tctcacatgc
     1441 agccactact gctataacat ttttctttaa tttactttga gatatagcac acatagcacc
     1501 tataacactc gcagcaccag ccatatctgt cttcatatct agcatagaag catttgattt
     1561 taaagaatat ccaccagtat cataagtcaa tcctttacct actaaaccta atatatctgt
     1621 actttcttta tctccaaagt atctcattac tatgaatctt ggtttattaa ttgagcctct
     1681 tgaaacagcg aaaaaagcat ccattcccaa tgcctttatt ttttcttctt cataaacatc
     1741 aacattaaac ccaaactctg caccaagttt aactgtttct actgctaatg tttttggata
     1801 tattacgttt gatggttcat taactagatt tctagctatt atagttgaat tagctaatat
     1861 tttagccttt tctatttgac actcaacttc tttttcagta aatatagtta tagtatcaac
     1921 ttcttttctt tcaaaatcct taatttttgt cttatactta tcaaacttat aatttccaag
     1981 taatatccct tctacaaaag aacctatttc atcactattt aaattaagat tcagtacatt
     2041 aacatcacta ctcttatatg cttcattttt caatatattt tttaattttt tacacaaatt
     2101 accacctatg attctaattt tttctctatt caataactct ctcttaccaa aaccaacaag
     2161 acaaacattt accaaattgt tattttcaat caatgttaca gtatctatac tattttcttt
     2221 agaattaaaa tttctgctta tcatatttat tttatcaaat gtcgtagaaa catcttctcc
     2281 ctcaaataga gctactactg ttatagcatt ttctaaactt tttaatattt ctttagaata
     2341 ctttatattc ataataaatt ctccttttta aaataattgt tctattatat ttttagactc
     2401 ttccaaagaa gtaaataatt tatctttatt atctatatct aggcaatcca ttttatcact
     2461 tattatagat acaaacttta gtatttcatt atccaatatc ttttctccat ttttagttat
     2521 tccataaaaa gtatttcgtc tatctctact atcttcttcc ctatatacat actcttgctc
     2581 aaccaattta ttaagtagta tacacagact agaagtagat acatgcaaat ctctacttag
     2641 atttttaagc tctattttat catgttttct tatttttact aaggcaaaga actgtctttc
     2701 tgtaagaacc ttatcttttt tatatctttc gttattaata atctttatta aattatgaaa
     2761 attattcata ctttctaaca acaaaataga taattcttta tcgctcataa cattcacctc
     2821 aaaactaatg atttataact ccctcttata tctcaaatgc gtttatatat ctataatata
     2881 atacttcttt tctttttata attatactat atatcaactt tattatctat ttaaattgtt
     2941 ttaaactaaa atcttattag atataaatgt ttaaagtaca caacaaaata gtgggattta
     3001 tactaacccc actactttac ctaaaactat atacatattt aaaaatattt tattcttaca
     3061 tattgttttt atcttgattc ttattacttt gtgatatatt ttgaattttc tccaatactc
     3121 taggagttat agataatata ttatccacta gattgatatt actgtctaaa ctcattattc
     3181 tagtctctcc actttcaact actacaaatg ctactggttg tacagatata gcccctgcgc
     3241 tacctccagc aaaattcgta tctgattttt cattttttaa ttcaatttcc ctatctttat
     3301 catcatatcc ttttgagtat tctcctcctc ctataccaaa gccaattgta acctttgata
     3361 taggtacaac cactgtagta tctgttttta tagggtctcc tataatagta tttgcatcta
     3421 tagaaccttt aattgtttca agagttgttt ccataagact ctgtatcgaa cctgttgctc
     3481 tcattactat caccttcctt atttccttta tttttattca taattttatt aatcattatt
     3541 ataatattaa ataaagcttt tattcttggc cttatatgta tccttatatt tcctaaaaca
     3601 taatcttttg taaaatctgg atttacattt aaatacattt tttctgcatc aatcatatta
     3661 aataaatttc catacaaagt atttatcaat acatatacag aagatgttaa gccaatattt
     3721 ccagttccaa aattaatatt tgaataaagt tcatgtattt ttatcttttt taataatcta
     3781 taaatgctca aaaggtcatc agctaataat atacttgaat ctatattatt cttcatcccc
     3841 tcttttttat cattattttt actattttca gctggataaa gttgtctatt tatatttatt
     3901 aaattaaaca tgtattttat attaagcttt aaacaaatat ctttgttttt tatatcagct
     3961 attattaaga tgtttatatg agatattaaa atcaacatag ttacacttat aataaaaatt
     4021 acagctatta ttaaatactt aaaattaaat aattcattaa gctccatgtt tatattatca
     4081 tcaaaaaatt actatttata cttaattatc catatttatt ttaagagaat tataatttta
     4141 tatttataca aaaaaacaca acaacttaga gcattttaaa tcttttaaaa tttaaaatta
     4201 catactaaat tattgtgatt ttatattttt attcatttgt tgccacttct tgataatttt
     4261 ctataggtgg caattcttca agactttcta tattcaacaa ctttaaaaat tcatctgttg
     4321 ttttataaat tattggtttc cctatcttat tcaatctacc agcttctctt ataagttcat
     4381 tttcaaacaa agtttgtaat accttatcac attttactcc tcttatatcc tctatttcta
     4441 cctttgttat tggttgtttg taggcaatta tagtaagagt ttctaatgta gcttggctca
     4501 aacttttctt tttctttggt tcaataatct tctttatata ttctgcatag tctttatttg
     4561 tacacatttg gtacttattc tctaacttga ttatttgaat acctctattt tgttctctgt
     4621 actcctcaat aagtaaattt aacataatct ctatttcttt tgatgaaagt tctttattta
     4681 ttatatagtt taattctttt atacttattg gctcaccata tgcaaacata acagattcta
     4741 taatatactt tatatcttct cttttcattt taacactccg aactttttct tattagaata
     4801 tcatcaaaaa atatatcttg tactacgact atttcttttt cttttataag ctctaatata
     4861 gataaaaaag tagctattat ttcatcattt tcatatgatt ttataatatt tgtaaaagta
     4921 acttcaatct tctcttttat aatatctctt atatataata ttttttcttc tacagatatt
     4981 attttcttcc ttactatttt atctagtttc tcatcattag cattttctat ctgtgatgtt
     5041 ttaactttaa atatgtatgg aagtatattt tttattgctt caattgatat atcttctaaa
     5101 tccacattgt catcaataat tatctcttct ttatttctat aaaatctctc attaacataa
     5161 gttatatttt cttttatatc ttgtgatgct accttaaact ttctatattc ttctaacttt
     5221 tccataagtt ctattcttgg gtcttcttct tcatcttttt gcttataaag cagatattta
     5281 gactttatct ctaaaagttt tgatgccata gttataaatt cactagttat ctctaaatcc
     5341 attttatcta gcattttcaa ataatttaga tactgcttag ttatatctat tatggatata
     5401 tcctttatat ctattttatg ctttgttatt aaatcataaa gtaaatctaa tggtccctca
     5461 tagacttgta attgtatatt atacttcata tcaatccctc tttaatctgt ttattatatt
     5521 aaacaaataa atatactatt tttagcaaca ctgcatatat tggtgttaat attattctat
     5581 acataccagt aaataaagca attaataaaa ttatataact catactttca aatttataca
     5641 aatattcatt ccatttatat ggtacaaatg tagatataac tccccatcca tcaagtggag
     5701 gtatcggaag taagttaaaa gctgcaaatc caatactata taaaaacaca tattcagcta
     5761 ttgtatttat agcatacata tgcacatact tattgataat tacacacagt atagcagtca
     5821 aaacattaca aaaaacgcct gcaagtgaaa ctatcaggtt tcctatctta tagtttttaa
     5881 agttatttgg atttactggt actggctttg cccaccctat cttaaggata aacatagcca
     5941 aaagacctat tgggtcaaca tgtcttacag gatttaatgt cattctacca taagctttag
     6001 ctgtatcatc tcccaataag tgagctgaat aagcatggcc aaactcatgt attgatattg
     6061 ccatagctat accaactaaa cttgctacta tttctcctat attcatactt aacattaatg
     6121 tacatctcct aaattaaatt tttaatatta ttataacaat taaatagctt ataatcaaaa
     6181 ttattttaca ttataataat tttaacttct aggcataaaa ttaaaatttg ctttttattt
     6241 tataactttt attattatat catattcatt gtgaaaatat aataattaca cctactgtaa
     6301 gtgtaatatt atattgacat gaattgacat tattgtctct tagtcaatat tatacaagaa
     6361 gtataaaaaa atatgtgtta cactttgtat aacatgaaag gaggttacct aagtgagaca
     6421 agaagaacgc acagtatgct ttgataggga attaaaaatt gaagcatata gatttaaagg
     6481 cataatgcaa aaattcccaa accattttca tgaacattat gtaattggtt ttatagaaaa
     6541 aggtcaaaga tatttatctt gtaaaaataa agagtatacc acaagtactg gagatttgct
     6601 actttttaac ccttttgata gtcatacttg tgaacaaata gatgataaag tacttgatta
     6661 cagatgtatt aatattaagc cagaaataat gaaaaaaacc gtctttgaaa ttacaggtaa
     6721 aaattattta ccaaaattta atcaacctgt tatatttcgc agtgagttag tacctctact
     6781 acaagaatta cactatataa tcatggaaga agaattggat tttaaaaagg aagagctttt
     6841 tttcttccta attgaacaat taattgaaga acatacagag ccaaatttgc aatctaactt
     6901 ggaaaataca aatatagaaa ttcaagcagt atgtgattat ctagaaaata attatgctga
     6961 acatataata cttgacgaat taagcactat agcaggtatg aataagtact ctctacttcg
     7021 taattttacg aaattaaaag gtattacacc atatagatac ctagaaaata tacgggtaaa
     7081 caaagctaaa aagcttttag aaaaaggcgt agaacctata gatgctgcga tacaaacagg
     7141 atttgtagac caaagtcact ttacaaactt ttttaagaat tttattggtc ttacaccaaa
     7201 gcagtatcaa aatatattta taaatgatga ttcaaacaac tttaaataag gtaaaaagga
     7261 gaaataaaaa tggaaaataa aaattcaaaa tgtgtcatgg taatagacga aaatttacca
     7321 atgggaatta tatccaatac agcagctata atgggaatta cactaggaaa acatgcccca
     7381 gaaactgttg ggccagatgt aattgacaaa acaggtaata gccacttagg aattattgac
     7441 attcctgtac ctattttaaa aggaaacaaa gaaataataa aagatttacg taaaaaatta
     7501 tatactttgg aatttaacga tttaactgtt gtagattttt cagatgtagc acaaagttgc
     7561 aatctttatg aagaatttac acaaaagatt gctagtgttc cagaagatga gttacagtat
     7621 tttgggatag caatttatgg gaataaaaag aaagtgaata aacttactgg tagtatgcct
     7681 ttacttagat aattgttaaa caaccctata tatgatatta aatcaaatga tattttaaga
     7741 tacataaact tttctatatt tctataaaaa tcataagatt ataaaatact tctatatagt
     7801 aaataaaaat acccctatgg caaataatta cataagggta ttttttatgt gtattataat
     7861 catatctttg tgtattataa ttatatttca tctgataatt atttatatca tattatcaat
     7921 tattctttga agcatttgta gatagcttgc cttatttata tctttagtat ttattaattc
     7981 cacttcgcct attacttttt tatctttaca tatctttatc tttcctaaaa cagttccttt
     8041 tttaattggc atcttaggat tttttactat ttcaattttc ttctcaaatt ctttagaact
     8101 tcctttttta ataagagcat ttaaatcttc tttagcaacc aatttaactt tgttttcatc
     8161 agccttatcc aatgtaagtg ttgctatatt atcaccttta ctacataact taacactttc
     8221 ataattagca aatccatagg ttaaaaggct agaggcatca ttaaatcttt ctggagaagt
     8281 ctctgctcct aaagttgcag caactagatg agtattacct ctctttgcag atgctgataa
     8341 acagtatttc gcttcttgag taaagccagt tttaacacca gttgctcctt gataatgctt
     8401 tataagtttg ttagtatttg caagacctac tgtaacttgt ttcttcccta ctacaacctt
     8461 atccatccat gtagttaagt atttacttat catttcgtgt tttaatagtt ctctagacat
     8521 taaagctata tcatgagcag atgtatagtg gtttgcaact ggaagtccat ttgtatttgc
     8581 aaaatgagta tcattcatat ttaactcttt tgctttagca ttcattctat caacaaaccc
     8641 ttcaacactt ccagctaagt gttcagccat agcaacacaa gcatcatttg cagaagcaac
     8701 agctatacct tttaacaatg tatcaacctt ttgagtttct cctggctcta ggaatatttg
     8761 actaccaccc atactagatg cagtttcact tacttgaact tcatcatcaa gtttaatctt
     8821 gcctgaatct aaagcttcta ctataagtag catagtcatt accttagtta cactagcagg
     8881 aggaagcttt ttatgagcat ccttttcata taaaatttgt ccactaccaa catccatcaa
     8941 aattgctgat tttgaagata tatttagttg gttggcatca gcattttcct tattgtttgc
     9001 aaaagaaaag cttaagggag taagcgcaat taatatagcc aaagcagtac tagctaattt
     9061 tttcatcgat gtcacctctt aaagtttatt taaacttatt ttctcacatt taactttttt
     9121 tattctaaat gcctagatat accttgacct aaattttttt tcttttcaag ctttttaaag
     9181 taaccttcta aaacaccttt attagacgca ttttctatta tttcaaaagc atcttcataa
     9241 ttcattccat actctcctgc tatttccatt tttgtttgtt ttaaagcttt tatagcattt
     9301 tgtcttgaaa catcatccat aagaatcctc ctatcagtaa aatttatata taagtagttt
     9361 ttactaataa aagattgtta taattggtat tttatgtaat atatatattt ttttaaatca
     9421 agtattaaaa agacctcttg taattcttaa gataatatca attggatttt tgatattact
     9481 ttaaaaatta caagaggtct aattttcaaa tttatagttt ttttatatta tacttccatt
     9541 atgataggaa gtatcattgg atttcgttta gttttttgat ataaatattc ttttaggttt
     9601 tctttaatat tattctttaa ataagcccat tctttaatat ttttctcttc acattcattt
     9661 agaacattct taattatatc ctttgctcca tccattaaat cttctgattc tcttacatat
     9721 acgaatcctc tggaaattat atctggacct gctaaaactt taccctcatc cttagaaata
     9781 gtaactacaa ctatcataag accatcttct gataaatgct ttctatctct taaaactata
     9841 ttacctacat cgcctactcc tagaccatca actaatatgt ttcctgtttg tatacgattt
     9901 gctaccttag cagagttttt atctaattct aaaacatctc ctgtttgcat gacaaaaata
     9961 ttttctttat ccataccaag ctgttcagct atttcagcat gtctttttaa cattctatat
    10021 tcaccatgag ctggcataaa aaactttggt ctaactaatg catgtataag ttttaattct
    10081 tcttgacagg catgtccaga aacgtgtata tcagctatat cactgtatac tacttctgct
    10141 cctttttcaa ataagaaatt gattactctt gatattaatt tttcatttcc tggtattgga
    10201 tgagcagata ttataactaa atcgccactc tttatttcta cttttttgtg ctctgaaaaa
    10261 gccattctag caagagctga cataggttca ccttgtgaac cagttgttat tatcactaat
    10321 tcactatctt catacttaca tatatcattt aaatctataa gcatgtcatc agaaatatct
    10381 agatatccta attcttttgc aactccaact acattgacca ttgagcgacc tgatatagca
    10441 acttttctat taaacttctc agcagtattt attatttgtt gtaatctgtg tatgttggat
    10501 gcaaaggtag caactataat tcttctgcca tttccttttg caaataattc gtcaagacct
    10561 accccaacag tcttttcaga catagtaaat cctggttttt ctgcattagt actatcagcc
    10621 agcattaaaa gaactccttt tttgctcaac tcacagattc tatgcatatc cataacatct
    10681 ccatcaatag gagtcaagtc aatcttaaaa tctcctgtgt ggtatattat accttggtct
    10741 gtgtgtattg caatagagta agcatctggt atactatggt tatttttcaa aaactctact
    10801 tccatattat caagctttat aacttgtcta ggacctataa catttaactt aacattattc
    10861 atcttatgtt ctttaagttt tacttgtata agacctatac taagtcttgc cccatataca
    10921 ggtacattta ttttctttaa tatatatgga agagctccta tatggtcttc atgtccatgt
    10981 gtaataaata taccctttat tttatcccta ttttttacta aataagttat atctggtata
    11041 actatatcta ctcctaacat ttcatcctct ggaaaactaa gtccagcatc tataacaatt
    11101 atttcatctt tatactcaac aacagtcata ttttttccaa cttcgttaag tccacccaag
    11161 gccattacct ttatcttatt ggtgttcttt ttgaacaatt gcatcatctc cttctgtcta
    11221 tttaattttt taacacgttc tacaatcata aataatatca aatcacgcac tcgctaccag
    11281 ttattcttat tgtaccataa ttcgtatcat attttaagct atatttaaaa tacatttaac
    11341 gtattatttt gacaaaccta ttttattttg atatcctcta aatattatat gatttaatat
    11401 cggataattt aggaggattt atgcgtggta aaactcattg tgcaatagga atcttaacag
    11461 ctatccagac atctttaata tttaaaattc ctatatcttt agttgatatt ttagtttcag
    11521 ctacttttgc tgtactaccc gatttggata aatctaattc tatggtctca aatttcattc
    11581 taaaaaacaa tgtatccaaa tacatatata gaatttttat atatgctgtt aatattatta
    11641 ttttctttat ttcaataaat ataaatgata atttttattt aagcgcaata attacatttg
    11701 ttgcaattat aattattgaa gcaaaactaa cccatacatt tctaagaaaa gtttttctat
    11761 cattaatatt tatactatta gctatatgct tatacatcat agaagttgaa atatatttta
    11821 caattttttg tctaatgttg tcaattttcc cctggttaaa gcacagaagt ttttctcata
    11881 gcatatttgc aactataata gtatattttt tactaaaaca gatagaatta atcactaata
    11941 ttaataattt atctttttat ggtacgattg gttatgcaag ccatatgttt ttaggagatt
    12001 tatttacaaa gcaaggaata ccaatttttt atcccctaag cgaaaagaaa atttctttag
    12061 ggtttttaac tgttggagga ccatttagta atttcataga aaaatcattc atttttgtac
    12121 ttataggatt aattatattt tcaatattaa aactataatc actttgaaaa ctgtatattt
    12181 gcattttata gatggtttat aataaaaaat ggaagaatag catagaatat aaaagttcta
    12241 tactattctt ccatcgacat taagcaatag aagtttattc ttctgaatcg cttactccat
    12301 tacactcgtc acatagtcca taaaatttaa catcatgatc aagtatttta aatttgtaca
    12361 atgattgtat ctctttttct atattgtcta aaaggtcttc tttagcttcc attatctttc
    12421 cacaattttt acaaataaga tgatgatgat tatgacagtc ttctttatgt agactaatct
    12481 catatcttat acatccatcg tctaagttta gttttgatat taatcctatt tcatccaata
    12541 gctgcattgt tctatataca gtagctaagc ctatttcagg acagtcaacc ctaactaaat
    12601 catagatttc ctcactactt agatgtgaat ggtcatgttt aagcaatatt tcaactattg
    12661 ctcttctttg tggcgtaatc ttaaaaccag tttcttttaa cttgtctttt aataaatcca
    12721 ttgtatttgc cataacatca cccttactat tttcaattga taatctttat taaataatat
    12781 tgtaattgat aattcatttt ttgtcaagac atttaaataa atttaattta ttctcataat
    12841 ataaatatat acccataaaa gatatattat tcaccaaaat tcataaattt tttggtattt
    12901 ttaataaaaa acaaaaaaac agatatatac tataaatgct tttacaatta ataaggttta
    12961 attaaagcaa atataataaa tatctgattt ttatatacaa acttaattac ttatctagtt
    13021 aagtccattt gattcatctt cgtcgtaatt taaaccttct tcttccatta tagcagtata
    13081 cacagctaca acagtttcat actcttcatc actttccaaa ggtattaaga tttcaccttc
    13141 ttcatcctca tcaattctaa agattaaagc ttcttcagct tcttcatcat ctaaaggcat
    13201 taatattgca tactcttttc cttctgcttc taatgttaat attatttcaa attggctttc
    13261 aacgccattt tcgtctatta aatttattat attttcttcc ataatgtcat tcacctcaaa
    13321 tttattttta tttttattat ttatattata tatcataagt attcaatttt atagttcttt
    13381 tatgaattta ttttaaaatc taaatatcct tgcaaaatta ttactgctgc caacatatct
    13441 ataacctttt ttcttttttg tctactaaca tctgcttcta ataaagacct ctctgccgct
    13501 actgtagaaa gcctctcatc ccaaaactct acatcaatac ctgtttctgc ttttaccaat
    13561 tcacaaaact tgattacttt ttctccttgt ggacctaaag ttccattcat attttttggt
    13621 aatcctgata caattttatt tacttgtttt tcttttatta ttgcttttag ctcttcaata
    13681 tcttttttct tgccaactct ttttattgtt tttacacctt gtgcagttaa tcccatcaaa
    13741 tcactcacag caactccaat agttttatca ccaacatcaa gacccattat tcttccatct
    13801 aacatagttc ctcctttatc tatttatatt ctatagatta aatacatatt ctgaacctct
    13861 cataactaag gtcacaggct tactgcttca tagaatttta cattatcaat cataaaaatt
    13921 gcaatatgat tttttatgta agcatccagt ttacattaat aatcatattg cattttttat
    13981 ttaaatccta tatgaacagt aaaaattttt ttagttattt ttttcaaata ttatcatatt
    14041 tatacttatt attattagtg gtataagtat atatatagat gctgtagatg cagcaactat
    14101 tccagaatca ttaactaaaa gagtaattat acaaccaacc atagatgcaa taaacccttt
    14161 aaacaagatt ggaaaattat tcattatctt tctaaagtgt ctagatggtt taaatataag
    14221 cactgcaatt actccaattc ctacaagtaa aatatttacc catacacttg tctgtgctag
    14281 ttgcatattc atttgaattt ttcttccaaa tgtttgtaat atctctcctg gtccatttag
    14341 gaaaattctc tgtacaaaca tacctaaatg agattcacta cctgaaagta tatctaaagc
    14401 tgcaaatgca aaaacgacaa ctacagctga aacagctaat aatacagctt tcttaaaatc
    14461 tattttaatg tcatatataa gcattataaa caacaaatat gctacacatt ctgatatagc
    14521 tccaccaaca tttgcaccca ttgaaggata tgcactagtt ataagtatta ttaatgaaaa
    14581 aattacaaca agtaatttag ataccttctt ataatgtaat aatactgcta agccaaatac
    14641 tgcacttgct atagttacac cttcatattc atttcctaca ccatagtacc tagctcctat
    14701 gacagcatca taactcatta tgttattttg cattaagtat gttccaaata cagaatctat
    14761 aactatgact aaaatagtaa gtgttgcaaa aaatcccatg tgctttatat cattgtcctt
    14821 aaataatttt ctacctaaca agtataatat tagcgtagtt gcaaatattc ccaaagatat
    14881 tgaaattgga gttttaaaat tcatcaaagg agctaacata aatgatagtg gcattattat
    14941 gcctaatttt ataaactcct taagtacttt gaatacacgc tctttatgtg gcatataatt
    15001 tctaaagaaa atcgcaaaca tggcaattac ccaagaagca gatattacgc ctacaaagcc
    15061 atttataata gttgacctta ttgaagatat agacactatc ctttcataaa gtgattttag
    15121 atagctaata ttgtcctctt tatttactaa agtataactt ctacctacca tctctttatt
    15181 ttcaagacca aatgtaccta gtatatctac tccaacatct aaattggcaa caattccagc
    15241 ctttcttgtt gtggcagatt ccagtagacc tttcccttct ccactaaatt ttattattgg
    15301 agaaagtctt ctcttattct tataatctag gtcacttgga aatgcacttg ctatataaac
    15361 agtgtcattt tctccaacca tagaaaatac ttgttcaaga tatttattta tattttttac
    15421 aatatttttc ttcattgtat cataagtatt atcatttaga tttaatctat acatatctaa
    15481 tctatatgta tctccaagtt ctacaaatat agcatcacta tttttatagg attttttagt
    15541 ttcatctagt aatttatcat aatctgtaga tattccaaat ggcattttag aatctttctt
    15601 attaatatta tcaatattac ctgaatcaat ccttccatat tggtccatag ctactaaaca
    15661 taagtttctg tttttaacta attgattatt ttcaattata tcagcatttc caattacaga
    15721 tgtctttaaa ccattttctg ataaagtttt tcctaatgac cctaaatttg ctccatattc
    15781 tccatactca agattttcat ttatagatct attaatgcct aaatcattta tttctttagc
    15841 tttttgacct gttgcgactt caaaagcttt agcagtatct tggtctactt tttgaaaatt
    15901 gatatagtct tcagtagtta cactagctct tgttcctgca cccatacttg cacaagacct
    15961 tctatcatca gtaccttgat cccctcttat attcatgaga gctacatagc ctctcttttc
    16021 tatctcattt ttcaagattg gaatattcat catacttcca agattggtcc tattcatatc
    16081 aataaatatg accttgcctt tttcttcagc aaaaccatag ctagcagttg atacaaaaat
    16141 cataatgact attgcaaaca acgacataat cttttttctc atttatttga cctactttct
    16201 attcagatag tgcgtgatta cttcttcaag tatctcatct ctttcaaatt ttttaattat
    16261 agctcttgca tttttatgac tagttatata gctagaatca ccagaaagga gataccctat
    16321 aatttgattt atagggttat atcctttttc aactaatgct ttatatacaa aatcaatagt
    16381 atctcctaca ctcatcctat cttctggtat tccttcaaat ttcatagtgt agtctaaatc
    16441 tttttccaaa ctaaaaacct ccttgagtga atgttattta acttgtgtct taataacctc
    16501 acttgcatag cttaaagctt ggtcaacctt agatacatca ctagctcctg cttgtgccat
    16561 attaggtctt cctccacctt ttcctccagc tatttttgca acttctctaa caatattacc
    16621 tgaatgtatt cccttatcta atacatcttt agtggcagta actacaaagt taactttatc
    16681 atctactaca tttgcaagta ctactacacc agaaccaagc ttatctctta gattatctgc
    16741 tgtttctctt agtgtatcca tatccatacc ttcaaattta ttagttatca aattaactcc
    16801 atttacttca actttagaat caaaaataga atcaactgat tgtaaactca tcttagcttt
    16861 catatcatgc aattctttag ataagttttt attttcttct aataaagaac ttattctttg
    16921 aattaaatta tcttctttag attttaagtt tacacaaact tcagagataa ttccatctct
    16981 ttcttttagg tattcataaa cagcttttcc tgttattgct tctattcttc ttacacctgc
    17041 tgctactcca ccttcagata atattttgaa cattcctact tgagaagtat ttgtcaagtg
    17101 agttcctcca caaagttctg tagaataatc tcccatagaa actactctta cctcatcacc
    17161 atatttttca ccaaatagtg ctgtagctcc tttttcttta gcttccttta tattcataat
    17221 atcacatttt atgtctaaag atgataaaat aacattattt actttttctt ctattacttt
    17281 taattcttca tttgatattg cttcaaagtg agtaatatca aatctaagtc tttctggagt
    17341 tactaaagaa ccagcttgat taacatgttc tcctaatact tctcttaatg ccttatgaag
    17401 taaatgtgta gcactgtgat ttcttgcagc tgacattcta gtttctctat ctacgagtgt
    17461 ctttactttg tccccattac ttattcttcc tgattttatt atacctatat gttttatact
    17521 attattagca ccttttttag tatttaatac ttctaaaact aagttttcat tagttatcaa
    17581 tccacaatct ccaacttgtc ctccaccttc aggatagaaa gtagtgttat ctagtactat
    17641 agatacctta tcgccttctt ctgcactttg aactagctca tcatctttaa ctatagcttc
    17701 aatagttcct tcaccataaa tttcactata cccattaaat gtactgtcaa ctgtagattc
    17761 taattttgat agagggtctt ccttccaact ttctccatcc atatttcctc tagcatttct
    17821 agctctttct ttttgctttt ccatttcttc attaaaagct tcttcatcta cagatagatg
    17881 ttcttcttct aatatttctt tagttaagtc tatagggaag ccataagtat catatagttt
    17941 aaaagcttct tgaccactta ggacagtctt tccttcattt tttaatactt ctatataaga
    18001 gttcaatatt tctgttcctt ggtctatagt ttcattgaat ttttcttctt ctattccaac
    18061 tactttttta atataacttt ctttttcaac taaaactgga tatgctttat catttacttt
    18121 tataacctca tctattagtt tctgtaaaaa taattctttt actcctaata acttaccatg
    18181 acgagcagca cgtctaagga gtcttctaag aacatatcct cttccttcat ttgatggaag
    18241 cactccatca ctaactaaga atgttacagc tcttatgtgg tcagttatta ttcttattga
    18301 tatatcattt tttggattct ctccatattt tactcctgtt aacttctcaa ctgcttctag
    18361 tatagattta attgtatcaa cttcaaagat agtgtctacg ccttgcataa tacatcccat
    18421 tctttcaaga cccatacctg tatctatatt cttgttttct aatagactat aatttccttc
    18481 ttcatctcta tcaaattgag taaatacatg gttccaaaat tctaaatacc tatcacaatc
    18541 acagcctggt ttacagtctg gattgtcaca tccatattct tctcctctat caaaatatat
    18601 ttctgaacaa ggaccacaag gacctgtacc tatttcccag aaattatcat cttttccaag
    18661 tctaaccatt ctttcttctg ggaaattcat ttcttttgcc catatatcat aagaatcatc
    18721 atcttcttca tatacagtca cccatatctt atcttctggt atatttagcc attctgtaac
    18781 aaattcccat ccccatttga ttgactctct tttaaagtaa tctccaaatg agaaattacc
    18841 catcatttca aagaatgtag catgtcttgc agttatacct acattttcta tatctcctgt
    18901 tcttatacat ttttgagatg tacacattct cacacttgga ggtacttcta cacctgaaaa
    18961 gtagtttttc aaaggtgcca tacctgagtt tataagtaac aaactcttat cattgtttgg
    19021 tactaaagaa taactatttg ctacataatg accttttgac tcaaaaaatt ctaaaaactt
    19081 acttcttatt tcatttaatc ccatcttttc catatcatgt tcctcctaat aaattttatt
    19141 ttttcgttta aataaaaaac ctcgtcccta taaataaatt tataggggcg aggacaatcg
    19201 cggtaccacc ctaattatca tacaaagtat gatatcttcg gaaaacctta gctataacgt
    19261 aactaccgtc aatctctact taaatcttct ttataaaaga taaattgttc aagattgcta
    19321 ctaaaaggct gcttcaaata tcatattcta agggcttcca gcatttccct ctctctgtaa
    19381 gacatcaaat attttactat tccttatcac tgtatttgtt ttttaattaa tatactaatt
    19441 atattactaa attttacaaa attaatcaat actatatttt catatacaat aaatttattt
    19501 tataaacttt atttactctt aatatacttt attgcttatt tttttaattt tttagatgtt
    19561 tttataaact tttctcgatt atacctccac ctactacaat atctccatca tacattacta
    19621 cagattgacc tttagtaata gctctttgag cttcatcaaa aactatttta atagtatctt
    19681 ctcctactct atgaatagta gctggtgatg gttttgctga atatcttatt ttggcttgaa
    19741 ctcttaaggg ttcttctaac gtatctattg atataaagtt aacatcttta gcaataagtt
    19801 cctttttaaa taaatcttca ttgtctccaa gaactatggt attatttatt ggatttatat
    19861 ctattacaaa cattggtttt ccaaaagtaa ttccaagccc ttttctttgg cctatagtat
    19921 aatataatat acccttatgt tttccaagta tattgccttt agtatctaca aaaaaacctt
    19981 cttcaatacg ctttttagaa tgttttttta cataatttgc atagtcatta tctttaacaa
    20041 aacaaatttc ttgactatca ggcttattgt gtactgccat acccatttcc ttagcaattt
    20101 ctcttactct atctttttca tagtcaccta ttggcaataa agtatgctct agttgctctt
    20161 gtgtaagatt ataaagtgca taagtttggt cttttttatc tgtaacagat ttttttagca
    20221 aatatcttcc tgtactttca tccttttcta tctttgcata gtgacctgta gctacataat
    20281 cacaacctat ttgtctagcc ttcttataaa aatcatcaaa ttttatatgt ttattacaag
    20341 ctatacaggg attaggagtt tttccttcca aatattcatc tataaaataa tctattactt
    20401 tttctttaaa cacttctcta aaatttaaaa cataaaatgg tatacctatt ttatttgcta
    20461 cccttctagc atcttcaaca gcagataaag agcaacaacc accttcaatt tcaacaacat
    20521 catcatcttg ccacaacttc atagtaacac caatgacatc atatccttgt tgttttaaaa
    20581 gatatgcagc tacagagcta tcaactcctc cactcatacc tatcattact tttttattca
    20641 taaacaaatt tcacctcatc ttttgcatta cttattatta taccatatag agcaagtatt
    20701 gtacttattt aaaatatagc ttgttctatt ttctaaaaaa ataatcatct ttattatttg
    20761 aatcttatgg attattttgt taactaatta acctctaaat caagttaaaa tacttaattt
    20821 aggcaataaa aaatagccat tttaaaaaca gctatttttt atgtcctaat tatatcatta
    20881 gtacttcttt ttaatcattg taaacttctc ataacacaat cacttatttt tattcttctt
    20941 cttcaacatc atggtcatga gcatcatcta taacatatcc atccaattct ggtatatgga
    21001 tattgttctt ttgagcataa tctataaggg ctgcttttac agcttgttca gctaaaactg
    21061 aacaatgcat ctttactggt ggtaaaccat ccaaagcttc tgcaacagct ttatttgtaa
    21121 gttctaatgc atcttttata gtttttcctt ttatcatttc agttgccata gaagaacttg
    21181 ctatagctga accacagcca aatgttttaa acttaacatc ctttattaca tctccatcta
    21241 tgtctaaaaa tatcttcatt atatctccac atgtagggtt tccaacttca cctacaccac
    21301 ttgcattatc aatttctccc atatttcttg gattcataaa atgttccata actttatcac
    21361 tatattgcat tatcttttcc tcctactcaa tttatgtcta ttttttatgc tttatcttta
    21421 tgtctatttt actaaacctt gtttcttcgc atcatcataa agtggtgaca tgcttctaag
    21481 tctttctatt acttttggta agttctctag tatataatct atatcatcat ctgttgtaaa
    21541 atctccaact gtaagtctta atgaaccatg tgctatttca tgtggtaaac ctattgcaag
    21601 aagtacatgt gaagggtcta atgaaccaga agtacatgca gaaccacttg aaccagcaat
    21661 tcctaacata tctaataata aaagtattcc ttcaccttct ataaattgga atgcaaagtt
    21721 tgcatttcct ggcaatctat tatctaagct accatttact cttgtgtaag gtattctttc
    21781 taacacacca tctattaact tatttctaag acgagttaaa gtttctacat gattttgcat
    21841 attttcctta gctaattctg ctgcttttcc atatccaact attgcaggta tattttctgt
    21901 accagctctt ttgctttttt cttgtgctcc accatggaca aagttatgaa gtcttacacc
    21961 ttttcttatg tataaagctc ctacaccttt tggtccatat attttatgtg aagacatact
    22021 catcaaatct attcctaatt ctttaacatc tactggaata ttacctgtag cttgtactgc
    22081 atcagtgtgg aataatatct tatgtttttt agctatttcg gatatttctt taataggctg
    22141 tatagttcct atttcattat ttgcaaacat tatgcttata agtatagtag tatcttttat
    22201 tgaatcttct agttgcttta agtctacttt tccttcgcta tcaacatcta aataagttat
    22261 ttcaaatcca tgatgttttg ctaagtattc acatgtatga agtattgcat ggtgctctat
    22321 ttttgaagtt attatatgat tacctttgtt tttattagca taagctacac cctctagtgt
    22381 ccagttatca ctttctgaac cacctgctgt aaaatatatt tcactaggtt cagcatttat
    22441 aagggctgct acttgttctc ttgctttatc caaagcatct tttgcttctc ttccgaatgt
    22501 gtgaaaacta gatgcattac caaaataatc tgttaggtat ggcatcattg catccaatac
    22561 ttctttttta ataggtgttg ttgcagaata atccatatac aatcttcttt tttccattac
    22621 attcatctcc aaatctattt tttaatattt gttatatcat tttctaattt atttttgtta
    22681 tagtcattta tcatatcttt aagagtaatt gaatctataa catcttctat accctttttc
    22741 atcttttccc aaactatttt tgttacacac atgtttgagt tttcacatac atcttcatct
    22801 agtacacagt cagataatgc aactggtcct tctaatacta caagtatatc tcctactgtt
    22861 atgtcttcag cattctttga aagcaaataa cctccttgag cacctctcac actttttact
    22921 agacccgatt tttttaaaga tgaaaatatt tgttctaagt actgatctga tattttttgc
    22981 ttcttagcaa taaattttaa tgatactggt ccattgtctt gatttaatgc taattcaaac
    23041 attgctttta gtccatatct acctttagta gacaacttca tatattatca cctctatata
    23101 gaaatctaat tcatactgtt ttagtaggaa ttactttcaa gataatttta ttatacccta
    23161 ctaattttgt caagattaat tttaattttt tattttgaat aaattcccca ttttccaatg
    23221 ttttcaaatc ctagtttttt atatatcttt ccagcctctt cattatcata aaacaaacaa
    23281 ggaattttgt tttctctcag taactctgaa catagtttaa ttaggcattt tgtagcaagt
    23341 cctttagctc tatatttagg atgtgttcct actccaatta tcattgcatg agtcctattt
    23401 tctgaagtac tctttgccat tgacaccacc tgtttgttaa tctctataca atatcctcta
    23461 cctgtcctta gtccattttt taaattctct aaagttgtac tgtgaaattc atctattaag
    23521 tcataaagtt tcactgtctt ttttagattt ccaagcctaa ttcttttaac ctttgcatta
    23581 caattattat ctatcaaaaa ctttttagtt tgaagtttgc aaaaatcaac tacctttaaa
    23641 ttattaagtc ctaatctctt tgctaaagca tctacagcac atattttccc agatatttct
    23701 tcgtaattag tattacgaag tagattataa aaaccttcaa catcatactc tccatcagaa
    23761 taaaatatca taaattcaaa atatttaagt aatattgcct ttatttcacc atgttcaccc
    23821 acatctgccc atatatttaa aaaattattt ccatatccat atctttcaat atcccctatt
    23881 ataaacaaat tgtactcagg ttcttttttt aagtatttca taactctact gtgataagtt
    23941 gagttaagtt ttataatcat aatatctacc cccgatacat aaagttcagt ctaaaaatca
    24001 ctatttagat attctaaata tttttttata tttttctcag ttttattttc ttgtggtatg
    24061 taataaatac tatcttttat gctatctggt aaatactgtt gctttacata atgattttta
    24121 aaattatgag gatatttgta tccacaaccc ctacctattt ctttagaacc agaatagtga
    24181 gaatccttta tactatttgg tatatcctta acaaactctt tatccagttc atccatagct
    24241 ttcattattg ctatacatgc agaattagac tttggagatg tagccaaaag aatagtagct
    24301 tctgctaatg gtattttcgc ttctggaaat ccaagttgca tagctgagtc tacacatgcc
    24361 tttacaatta caatagcatt tggataagct aaacctatat cttcactagc tattactaaa
    24421 agtctcctac atatacttat caaatcccca ccttttataa gtcttgctag atagtgtata
    24481 gatgcctgtg ggtcacttcc tcttatagat ttttgaaatg cacttaaaat atcataatga
    24541 ctatcaccat ttttgtcata gtttataatt ttattaaatg tagatgccct tattacatct
    24601 gaatctatat aagttatatt atccttattt ggtttagttg aatagactac cacttctaaa
    24661 atatttaagg ctcttctcat atctccatca gaaagaattg ctatatcttc aatagcatta
    24721 ttattacact caatatccat atagctatct tcatttaata cttcaacagc tcttttcagt
    24781 cctttttcta catcaagttt ttctaaaggt ttaaattcaa atacagtaga cctacttaaa
    24841 agagctttat atacataatg atatggattt tctgtagtgc tagcaatcaa agttatactc
    24901 ccattttcca taaattctaa tattgattgt tgctgttttt tattaaaact ttgtatttca
    24961 tctatatata ataggactcc atttacatta tttatacttc caagctctga tatcaccttt
    25021 tttatatctt ctaaagatga attagtagca tttattttat agaagctttt attgcttctt
    25081 tctgctatta tttccgctac tgtagtttta ccaacaccag gaggaccaaa aaatatcata
    25141 tttggtaaaa aattagattg taatatctta gacaatattt ttccattacc tattatatga
    25201 ctttgaccta ttacatcatt cattgttttt ggtcttattt tatctgctaa aggcattttc
    25261 tcactccttt ttaatatact tatcattacc ttaataattc gtctaaaaaa ggtatctatt
    25321 tgaaatagat accttttcta atctaaacct ataaaatata gattattgat tgttttttaa
    25381 tttttttaat tcatctgtaa gtttgtcatt aagtattctt atatgagtac ctttcatacc
    25441 taatgatctt gattctatca cacctgcact ctcaaatttt ctaagtgcat ttactattac
    25501 agacctagtt ataccaactc tatcagctat cttacttgct acaagtagac cttcttttcc
    25561 atccaattca gcaaaaatat gttcaactgc ttcaagctcg gagtaggaca gagtgcctat
    25621 tgccatttga actacagctt tctttctcat ttcttcttcc aattcttcac ctattgctct
    25681 taatatttca agaccaacaa cagttgcact gtattcagct attactaaat catcatcatt
    25741 gaatgaattt gaatatcttg aaagtaccaa tgttcctaat ctttgaccgc ttcctaatat
    25801 tggaactact gtagtatatt tttgtaatct tccatgttct tcaggaaaga tttctaatat
    25861 cttctcacca tttaaatttt ctaatgtttc atcaattttt aacacatttt gagtatattc
    25921 atctgaaaat ttcttttgct tagtatactc atcttctata actgaactgt cttgaacatc
    25981 atttaaatga agacctagta ctttaccttt tgcacttact acataaacat tagaacttaa
    26041 aacgtcgccc aatgctccgg ccagtaaatc aaaagagaca ctgcttccac cacttgtttg
    26101 taatgtttta tttattttcc ttgttttttg taacacttca cttgccattt aatcatctcc
    26161 tcatgaaatt taggcctttt aataaccttt tatattttct aatattattt tcacatttaa
    26221 tgaaaattta tttttctatt agttgtttac acttgaaaga ttatcataga ttggaacctt
    26281 tttcaagaga attatgtgat ttttttcaat tttcactctt ttccgtcatt atgctctttt
    26341 gtctctttat tacattcttt attagaacac actgtttttg tttcagattt agtcactttt
    26401 tcaaccatat atgaaccaca cttctcacaa aactctcctg ttggcttatt ccaagctaca
    26461 aagtcacagt ttggataatt agaacaccca taaaaagctt tacctctttt agattttcta
    26521 agtataatat ctccttcttc acattttgga catttaacac caattttatt cataattggt
    26581 ctagttgttt tacaatcggg atagttttta caagccataa actttccaaa tctaccatat
    26641 ttgataacca tattagaccc acagttctcg caaatctcat cagtttcttc atccatattt
    26701 actttttcta tattttcaag agcttcttca atagcctctt taagtggtgc atatgattct
    26761 gatacaatct ttttccaatc tgtattgcct tcttctataa catcaagttt actttccata
    26821 tcagcagtaa aatctacatc tataaattta tggaaattat tttccaaaat atcagtaact
    26881 attattccaa gttctgttgg acatagactt gttccttgct tttcaacata ctctctattc
    26941 agtatagtag ctattgttgg agcatacgta cttggtctac ctatacctag ttcttctagt
    27001 gtttttacta aactagcttc tgtatatctt gctggtggtt gtgtaaaatg ttggtctggc
    27061 aatatatttt ctatatttaa tatatctcct ttttctatac ttggtaaaat tttgtcttct
    27121 ctttctgaaa aattatatac cttggtataa ccatcaaatt tcatttttga accagttgcc
    27181 ttaaatacaa tatcgcctat tttacattct acatttagta tatcaaacac tgaatcttcc
    27241 atttgactag ctacaaatct tctccaaatt aaattgtata acttgtactg gtctttgctc
    27301 aatgaggctt ttatactctc aggagttcta tcaactgagg ttggtcttat tgcctcatgg
    27361 gcatcttgaa cctttttagt atcctttttt tcttttttat caccagtgtt tttatagtag
    27421 ttttctccta aattgtttac gatatagccc ttagcttttt cttttgcttc atcagatatt
    27481 cttttagagt cagttcttat atatgatata agaccaacag taccttcacc ttctatgtcg
    27541 ataccttcat ataattcttg tgctatcatc attgtttttt tagtagtaaa aaataactta
    27601 tttgctcctt cttgttgaag catacttgtt gtaaatggtt ttggagctga tttacgtctt
    27661 gatttagatt ctatcttctc aacctttaaa tctttacctt ccatttcttt tagtatttca
    27721 tttacagctt cttcattttc taattcaatc ttttcatcat ttttaccata aaatttcaaa
    27781 gttatatctt tgtcttttac tgtcttagcc tcaacatcta ttgtccagta ttcttttgga
    27841 ataaatgcct ttatttcttt ttctctgtca caaattaact ttgttgtaac agattgcact
    27901 ctacctgcac taagaccttt tctaaccttt tgccataata taggacttat ttgataacct
    27961 aaaagtctgt ctagcactct tcttgcctgt tgtgcatcaa ccaaatttat atcaatattt
    28021 ctaggatgtt taattgcttt tttaattgca tccttagtta tctcattaaa ctctattcta
    28081 caatcctcag attcatctaa atttagtata tgagctaaat gccatgatat agcttcacct
    28141 tctctatcag ggtcagttgc tagatatact tgtttagatt ttttagcttc tttttttaat
    28201 tcttttatta catcgccttt tcctcttata tttatatatt gaggttcaaa attattttct
    28261 atatctacac ctaatttact tttaggtaaa tctctgacat gaccaactga tgctttaact
    28321 gtgtaatgac ttttccctaa aaatttttct atagttttag cttttgcagg cgattctacg
    28381 atgactaatg ttttggccat aaaaccatac acccccacta cctaatctta atttatacat
    28441 ttaaactgta cgttttatta ttcatttcta ctactaactc atttagtact aattcattga
    28501 ttattgaatt tacatacttt atttctatac cagtataatc acaaatacta tctatatgca
    28561 agtttccttc tctttttata gcttcaatta tttgcttaga cttggcattt agacttatat
    28621 tatcatattt ttgatttatt tttttatcaa taatattaaa tatgttatat tcatttaaaa
    28681 tatcatctat attttcaatt aattttgcac cttcttttat aattttatga caacctctac
    28741 tcatttgaga atttatatta ccaggtattg caaaaacatt ttttccatgt tcaagagcaa
    28801 aatccactgt gattagtgca ccacttttta ttgctgcttc tacaacaact actccatcac
    28861 ttaaaccact gataattcta tttctattag aaaaatggta cggggctact gtcgagttaa
    28921 tattatactc tgataataat aatcccccat tttctaatat tttatttgat aaatgtaaat
    28981 tttgttttgg aagaggattg tctactcctg aaccaagtac tgctatagtt ttagattttc
    29041 cactcataca acctatgtgc gagtatgcat ctattcctat agctaatcca cttactatat
    29101 taactccata ttgggatagt tgacaactta ttgtttttgc acaattaatt ccataggctg
    29161 taggttttct tgaacctact atagctatat taaaattatt attaactaag cctatgtcac
    29221 ctttgtagaa taataacttt ggagcgttgt atatattctt taaattttca ggatattctt
    29281 tatcatattt acaaatatat ttaatcgctt ttttgtaaag tagttctttt atattttcta
    29341 aataagcgtg acctctatat tttactatat tttttctaat attcaagctt atatttttta
    29401 aattatatat ttctttttca gaaaaatcaa atatatcttc aatatttact atttcatttt
    29461 ctattatttc aattgttttt gttgttattc caccaattga ttttaaccat aaataagtat
    29521 ctcttttttc cataaaatcc acctcaaaaa actatttaaa ataactataa taagcctttc
    29581 taaatgaaaa agcttctata atacactgtg aatttatcaa gtctctttct tctaaatctg
    29641 ctattgttct tgccattttt aaaagttttg tataacttct actgcttagg ttgtatttat
    29701 taaatatcat ctcagccgtt tttgaagctt ctttttccag tttacaatat ttaaataaat
    29761 tgtaagcttt aatttcacta ttatttttta tattatcctt cttaaatcta tttatctgta
    29821 tttttctagc attttctact cttctcttta ttttttgaga gctttcttct tgttttaaag
    29881 aattaaaatc tgaatatttt atagaattaa cttctacaaa aatatcaaac ctatctaaca
    29941 atggacctga tattttattt atgtatctat caatttcgtt acttctacat ctacactctg
    30001 tctctgacat ataataacca catggacatg gattcatagc tgcaactaac agtactctac
    30061 aaggatattt tgcactgtac tttactctgg atatatttac atatccatct tctataggtt
    30121 gtcttaaagt ctcaagtatt tttctatcaa attcggctat ctcatctaaa aataagatac
    30181 ctctatgtgc taaagcaatt tctccaggtc ttgcatccat tcctcctcca attaaagatt
    30241 gctttgtagt tgtatgatga ggtgctctaa aaggtctttt atcaattatt cctttagttt
    30301 catttatcat acccaatata ctatagacct tacttacttc tatcatttct tctacactta
    30361 tatctggtaa aattgtcctt actctttttg caatcatagt ttttcctgag cctggaggtc
    30421 caatcataaa catattatga tttccagcag cagcaatttc tgcactcctc tttacaaaat
    30481 aatttccttt tacatcttta aagtcttcat catatttact ttcttcatta ttaatcttag
    30541 tatatttgca atctatataa ctattatctt tttctaattc ttcgttctct tttcttgact
    30601 tatcatccaa aaaagacatt atccttactt tatcgacttt tatctcttcg tttaaaaaat
    30661 cgacacattc ttttaaactt ttaataggaa ttatatcaat ttcatctaca aatagacttt
    30721 cttttatgtt ctcaattggt ataaaaatac gttttatgtt ctgagttttt gcacccataa
    30781 ttatgggcaa tatacctctt acttttctta ttttcccatc taatgataat tctcctataa
    30841 acatactttc tcttatgtaa ttttcatctt tttttattaa ctctcttaaa aggcctatac
    30901 ttatagataa atctaaaaaa gctccttctt tttttatatc tgctggtgat aaatttacaa
    30961 ctattctcgt gcttggaaat ttatatccac tattaagaat tgctgacttt actctttctc
    31021 ttgcttcttt aatttctttg cctggaagac caacaatatt aaaactaggt attccattgc
    31081 ttacatctac ttcaacctta actaaaaagc tgtcgattcc tactaagttg cttgaattaa
    31141 taatacttaa catatttaat cctttccaaa aacattatct tttttaaaaa gcattcatta
    31201 tgtgatttat tcttttttct aataaatata cctctataac atcaaatctt acgggagtgt
    31261 tatttaagtt attttttata atataataat ttgcaactcc aattatcttt tttctttttt
    31321 tgaagcttac agattcacaa gggtagccaa actttatgtt agaccttgat ttcacctcca
    31381 caaatataat ttcatcttcc atttttgcta ttatatctat ttcccctatc tttaatctgt
    31441 aatttttttc tagtatcttt gctccttttg atagcaaata attaactgct actttttctc
    31501 caaaatcacc tttttcttta ttattcatta ttcactccaa tacattaaat tttcactttt
    31561 aaattattgt cagtatacaa ttttactatt caagtttttg gattgatttt atttccatca
    31621 atattaataa atacttttat tgactttatt cttttatgat attattctag ttttcatagt
    31681 aaaagtttat ttttttggag gagtgccttt aatgaacaga gaaaaattag ttgcttttat
    31741 acgatattta tctttattta tattagttgt aagctatttg aaaaatgttg aaaatacatt
    31801 gtatccggtc ataactatga taatattatt tctaattata ataaataatc aagttagatt
    31861 tttttcttta tcaaatgaga ataaatttat acttatttct tactttttag aacttatatt
    31921 aatttttata ctttgtaatt atacaaaaac ttttaattcg atttactttg ttcctttaat
    31981 attagatata tcatttttaa taaaggaaaa atataagtac atattgttct cttttgttat
    32041 aatatcttct cttattatta gtttagataa aaatatatat ttggcactgg agtcaagctc
    32101 tatattgcta attataactg tactttctat atatatagaa aatgagaatt tatcaaaatt
    32161 atacagtcaa aatctttatg ataagcttag aatttctaaa gatgaattaa aaaaagttaa
    32221 tgctgatttg gaaacttatg caagttctat agaagaatta gcaattttaa aagaaagaaa
    32281 tcgaatatca agagaaatac atgatagtgt aggacattct ctttctacaa caataataca
    32341 attaaatgct atagaaaaac tcttaaaaga caaacctcta atttatgact tagtacatga
    32401 acttagagaa tttgtaactg aaagttttca agatgtaaga agggctatat ctgagttaaa
    32461 acctgttgaa tatgaaaatt accaaagttt atttaaaatc aaagaattag ttaaaagctt
    32521 tattaagctt acaaatatta atgttaaatt aactatttca aaaaatactt ggaacttatc
    32581 cagaaatcaa tctataactt tatatagact tatacaggaa tccctttcca actcatctag
    32641 gcatggaaag gcaactgaaa tcagaatttt tattacattc aatacttcaa atcttataat
    32701 tactattagt gataatggta taggatgtgg caatataaaa aaaggaaatg gacttaatag
    32761 tatcaatgag agaatatatg aattaaatgg taaagttgaa tttgataatt ctaataatgg
    32821 tttcacaatt agagcttctt ttcctaaatt ttcagggggt gatttttttg aataaaatta
    32881 aagttcttat agtagatgac gaaaaattaa ttagaaaagg tcttaaaatt atattatcat
    32941 cttataatga tttagaaatt gtaggagatg cttctaatgg atatgaagct ttagaatttt
    33001 gtaaaatgaa tgatgtagac atagttctta tggatatacg aatgaaagta tgtgatgggg
    33061 ttctaggtac aaggcttata aaggaatata ataattctat aacattatta attttaacaa
    33121 cttttaatga tgatgaatat ataaaagatg ctatgaagtt tggtgcttca ggataccttt
    33181 taaaagatag ctctgatgaa gtattgcatg aagggattcg ttcttcattt tttggcaata
    33241 ttgtgcttga taaaagtgta gctgaaaaaa tcatgacctc tgaaaaaacg gttaaacaag
    33301 agcatcttta tgacatgtac aatttaacag aaaaagaaat atctataatt agactaattg
    33361 caaatggact taataataaa gaaataagtc aagaactatt cttatctgaa ggtacaataa
    33421 agaataatat aactaatatt ttagctaaac tagaacttcg tgacagaact caactagcaa
    33481 tctttgcttt caaaaataaa attgtaatag aataaatcta aaaatataaa gtgacttaag
    33541 tcactttttt tagtgactta tagtaataga attataattc acaattcttt attataatat
    33601 tatagctttt taacttatac aaaattattt tggagggatt actatggata tagtcagagt
    33661 aaataatata acaaaaagat ttaatgataa attagtactt gataacatca gcttttctgt
    33721 taaaaaaggt gagatatttg gacttattgg cccaaatggt gcaggtaaat ctacacttat
    33781 aaatataatt acaaatctta tgttaccaaa tagtggtagt attcaaatca atggtttaga
    33841 tttatcaaaa gattatataa aagcaaagtc tataataggg ttagttccac aagaattagc
    33901 aattatagaa actcttactc cttttgataa cttagagtac tttggagctt tctacggttt
    33961 aaagggaaaa ctacttaaag aaagaatcat tgaagcatta gaagttacag gtcttactga
    34021 agtcaaaaag aaaaaggtca aaaaattatc tggtggtatg caaaggagat taaatattgg
    34081 aatagcactc ttaaatcatc ctaaaatatt aatattggat gaaccaactg taggtgtaga
    34141 cccccaatca agaaatcata ttttcaattt tataaaagat atatctaaaa aacatgaaac
    34201 tactgtaata tatacttccc attatatgga agaagttgaa cacctttgtt ctaaaatttt
    34261 tattatggat gaaggtaaag aaattgcttt tggagataat gattatttaa aatcactcgt
    34321 atctacaaat acaaaattaa ttatagaaat aaaaaatata aatgcccaac ttatctttga
    34381 tttaaaaaat actaaaggtg ttatatctgt tttagaaaat aattcattat tagaattgga
    34441 tatagataaa aaattacaac ttacagatat actctctgtt attgacaaaa acaattcaaa
    34501 aataatgaaa atttcttatg aagaacctag cctagaagac gtatttttaa atctaacagg
    34561 aaaaaattta agggactaat ggaggtgatt ttatgaaatt atacatgagt gtaaaaacta
    34621 tgctaaagag tttaaaaagc tcctttatac ttaatttaat atatttttta gctttgcctc
    34681 tgattttatc ttggtttctt gggatggtta cagaaagcat gtttcaaaac cctataaaaa
    34741 cagaatctac ccccattgtt atatatgaca aagataacac aagattatca aatgatttga
    34801 caaagtattt gaaaaatgat ttatcttata tattaacagt taaaaaagat gattctaagg
    34861 cagaattaaa gcttactata cctaaaggct atgagagtag tttattaaat gaaaaatcaa
    34921 atactctaaa catagaaaaa cttggaactc gtgatgatat tgcaatattg cttcaagata
    34981 tattagatac ttaccatgaa aaattttatt taaataattc tcagaaaata agttcagaag
    35041 atttttctaa attatttaat aaaaattcta ttgatacttc tataataaat aacaatgtta
    35101 aacagaactc ttatgaatac tttgctttag tttcactagg atttcttgta ataattttta
    35161 taatgaacaa tattttgtca aattatataa gtgaatcaaa gggactttca aaaagacttt
    35221 attctatgcc tataactaga gtacaattct taatttatga ctttgtaggt ttatggattt
    35281 attcatttat attcttatta ttatatgttt tattctttag aatacttgga ataacattta
    35341 aaggtaattt tgccatattg ctcctacttt gtgctttatc atcttatttt atgacttcaa
    35401 tatctacctt tgtaaccagc ttttttagta aaaaatacgg tacagcaata gtttatgcat
    35461 tactcttttt acagacaatt tttggaggta tcttcagtat gataagtgat acatttacta
    35521 agcttacaag tttatctcct acctatttaa taggagaatt gtttagtaat tatgaaacat
    35581 ttaaaactat agattcaata ggagatttaa ttttcacatg tttaattatc tctacaatat
    35641 taattgcact tgctattgta aaggaaaaat ataaatggag ggaggtttaa taatgattag
    35701 attaactatt gcaaatataa aaagatatct aaaaaatcat aatcttttaa ttaatatggt
    35761 tatgcttcct attatactaa ttttttcact taattttttt atcaacaact caggaaatca
    35821 atcaatgtac ttttctccag tagcaattgt atctgactct tcaggaaagt atgaacataa
    35881 gttaataaat agttctaaat taaaagaaaa ttcatttaga ttaaatgaac tagataaggc
    35941 tatgaatcta ttaaaaaata ataaggtttc tgctgtattc gttttagata aaaatttttc
    36001 aaatagtata gataaattac aacgacctgt agttaaatgc tttaaaattg aaaatggtgg
    36061 tggtagtctt tgggcagaat cacaaataga atcttttatt actaaatcgt taaaattgaa
    36121 agtggataaa aatatagatg ataaattgac aaagacaaat ataattgata acaaaccaga
    36181 taagaataaa ggttcatttt tagtagtctt cttgatatgc tattttatgt atattaatgc
    36241 agcacatctt gcttctgatt tatttacatt aaaaaaatca aatgtgctaa aaagacttat
    36301 ctctacagat aataaagata taaaaataat tttcagtata tttttaggac tattttttat
    36361 tcaatcaatt gtatacactt ttgctctatt atgtttttca attatagaag actttaattt
    36421 gagtctgaat gtattgatga ttgtactagc aaatagtttt gtttccactg gatttgtatt
    36481 ttgggtagct agagtattta aaaatgaaag ttctataagt cttatatcta cattttattc
    36541 tttaataggt ctagctatat ctatctctag tctaatacca tcaatggata aattatcctt
    36601 tatgactaat ctttcaaagt tcacaccatt ttattggact atagatgcta ttaaaaacaa
    36661 tggtagtatt ttaataaata taatagctct aatattaatt ggaattatat ttgtaactgc
    36721 aggaagtctt aaactaagag attttgctaa aaactaataa ttattaaata taattagtat
    36781 ctatttttat atagttgtaa aagaatattt caacatatta aattatttta tcttatattt
    36841 ttctctttag tttcacacat caccaagtct aaaccttata ttatatatta atatttttga
    36901 cttgtcaagt tatttatgtt ataatattaa tcattagata attaaagcat tgtacctaag
    36961 ttgcaatatc taaaattcaa tttggaggta taactagcat atgtataaaa ttggtgaaag
    37021 tgtaatgtat ccaaaagagg gagcctgctc tgtaaatgat attgtaacaa agaaaataaa
    37081 tcatgagatg caaaaatact atgaattaag tgtcattttt aatagtaacc ttaaaatttc
    37141 gattccagtt ctaaatgcag atagaattgg catacgtcca gttatggatg gaaatgatgt
    37201 tgataatttt atccaatcta ttaataaaac agatggtgta tggatttttg atagaaaaga
    37261 aagacttaaa ctgtaccaag ataaatttca ttcaggagat gtttttgaaa ttgtaaaatt
    37321 aatcaaaatg cttatgatac aagacagttc aaaacaattg tgtagcacag ataaggagtt
    37381 tttaaataaa gctcaaaaat ttgctttatc agaattagct gctgctcaat gtaaatccta
    37441 tacaatggta ttagaggaaa tgaaaaaaca tatattaaat tcaaagaata caaattaaac
    37501 cagtttttta aactggtttt attttttata ctaatcatcc atgctacttt agcttatttt
    37561 aaactgccta atctaatatt aataaagtta tctcaattag atagatgtat tttattcaaa
    37621 taaaaaaaac taagagtaaa tcatattact gatttactct tagctaataa aatttaatct
    37681 tcttcaagtt cttttttctc ttgtaataat acacttaatt catttgcttc taaaacttgt
    37741 gcctctgcaa tatcaagtaa ctcttgttgc cattccacac atttatcttt gtaatcaaaa
    37801 ggtagcgttc tgtcaactat gtacttatca atacagtcct ccgcactttt aattatttct
    37861 tttctttcat caataaattt ttctaattct actaaggctt cttcataagc ttttctactc
    37921 atataaattc cccctttgta caattattct acattaaaat gatttttcct cttttttgta
    37981 taaaatttta tttgtatata acttttccat caatatcttt tatagtttga catccagtta
    38041 atatcataga actacttagc tctgattgaa gtttatttac ataagtttct acaccatcag
    38101 ttgcaccacc aaaagaagca gtcacaaaag gtcttcctat taatactgca tctgcaccta
    38161 aacctatcat ttttagtacg tctaaaccag ttctcactcc accatctgca agtattgtaa
    38221 ctttaccttt aacagcatca gcaatttttg gtaaaacttc acatgctcct ggtgtacagt
    38281 caagcactct tcctccatga tttgatacaa ctattgcatc cacacctgct tctactgcca
    38341 ttaaagcatc ttcaacagtc attatacctt tcaatataaa tggtagttta gtagacttta
    38401 ctaactcctt tatttgttta acatttttag gaagtactgg ttttccatgt aatgataaag
    38461 ttactagacc acaggcatct atatcaactc caactgcaaa tgcaccagct tcttcagcta
    38521 atcttatctt ttttataata ttttcattat cccaaggttt aataaataca attccagctc
    38581 cattatactt tttgactaca tctaaatttt ccattaaaaa agcatctact gccgtatcac
    38641 caaccattgc ataaatacca ctattagcac atcctgcaac tactggttct atgtaatctc
    38701 tttcattaat ttttccaccc atatttaaag tagttcctgt tactggagct gcaaatatag
    38761 gtgcactcat tttctttcca aacatctcta tagatgtatc aggatttgat acatcatgta
    38821 ttactctcat atttactttt actttttcta aactcttgct attttctata aaagaagaac
    38881 cacttccttt acctcccatg ccaggcactt cacctgcaca agcaacccca ttacaaacct
    38941 tacaaacttt acaacttcca tttaaatttt ctctagcact ttttaataat tcattatatt
    39001 ccatctttaa tcccccatta actatagtaa tttatattat atacattata tcatattata
    39061 tttacagtat atttttcaaa aaactttttc tgtggatagg agttatgcca tatttttcaa
    39121 tagcttcata gtgttcttta gttccatatc ctttgtgaga tttaaaccca tattctgggt
    39181 atactctatc atattggtac attatactat ccctagtaac tttagcaagt atacttgctg
    39241 ctgctattga tatagatttt gaatctcctt tcacaattgg attttgagat atgtcaatac
    39301 ctggtattgt tgctgcatca actaataaat aatccggtgc tttttttaaa caatttatag
    39361 cctttttcat tgccatatat gtagcattta atatattaaa ttcatctatt tcttcattgt
    39421 ttactatacc tattccataa tctagtgctt cttcttttat tacttcaaaa agttcatctc
    39481 tttttgcctc actcagtttc ttagagtcat ttacaccttc tattttggta tcttttttaa
    39541 atactacaac agaagctaca acaggtccag caagtggtcc tcttcccgcc tcatcaattc
    39601 ctccaatata taaataacct ttatcatagc cttcgttctc aaatatattt atagtttcca
    39661 atctttcttc ttcttttcta atattatcca gcttttttgc tagttttata gctagacctt
    39721 gtacagattt tctttcatca actcttaaca gctctatata ttccatatat ttttctactt
    39781 ctaaagtctc tattatttct ttaatctccc tcacactttt atcctgcata ccattccctc
    39841 atctttcgtt tttaaaaatt taatttttaa atatattaaa attttttaat tagagtttaa
    39901 ttgcatccac tatagccaca ttttaaacat atactacatc cacctgtatg tgcaattcct
    39961 tcacttccac actcaggaca cacaaatttt tcatcttctt caaaattttt atttattatt
    40021 tctttggctt tttcatcttt attatctttt tcttttttat tatttttata atattctttt
    40081 ttactatttt cttttttatc ttctttatta ttttcttcct ttttttcatt tattaaaatt
    40141 ccactccttt tacatccatc tctaaatatt gttactcctt taagaccagc ctcccatgcc
    40201 ttaatatata tattgaaaac atcttcaact gtagtttcaa aaggtatatt tattgtagat
    40261 gatatagaag catcaatata cttttgccat actttttgca tgtttattct ttcttcatat
    40321 cctatattca tagcagtaac aaaaaaatct ggtaaacatt cttcatctgt aatacctttc
    40381 ttgtccatat actctttaac aattggagta tatactttat aatacacatc ctcatcatgc
    40441 aagctttcag tttttcttat atatgaaaga ttaaatatag gttctattcc accactaata
    40501 cctatcattg tagatataga acctgtagga ggtatggtta aaagttgtga atttctaagc
    40561 ccatactttt taaccatttc cttagtgtct tcatttagat tttctataaa aaacttagat
    40621 ttagaaatat tttcatattt atactcacta aatgttccat attctttagc aattagtgct
    40681 gattgcttca cagcttcatt taacatagtc ttaccaatta aatcacatag ttctaaagat
    40741 tcatcagaac catatcttat tcccattttt ataagcatat cagctatacc cattacacct
    40801 aaacctatct gtctatactt atgtacacta tctctttgtt cttgtaatgg atgcaagttc
    40861 aatccctcat ctaagacatc atttaaagct actacagctt ctctaacgca agattttaat
    40921 ttattaatat caaaagtagc atgttcacca aatggttgta ttataaactc tgacaagttt
    40981 attgagccaa gtagacaact tcctccactt ggaagtggtt cttctgcaca aggatttact
    41041 cctgaaaagc aaaagttctt atcttcactc ataaaattat atgtttttat tttatcccaa
    41101 aacaatatac ctggttctgc ataatcccag ttatttttca caaatttatt aaataaatca
    41161 taagcattta ctatcttaac tattttttct ccagtagttt caacttcaaa agtacaatta
    41221 tataactttt tttctcttac agcttgcata aattcatctg ttactcttac agaaatattt
    41281 gctttagtaa ccttctccaa atctgttttt atatctataa agtcttctat ctctggatga
    41341 tttacatcca tagaaatcat aagagctcct cttctccctc tttgaccaat taagccagtt
    41401 gtcatactgt aaagttccat aaaagagact gctccagtcg tatgttttgc agcattgtta
    41461 actttcgctc cttttggtct tagctttgaa atatcaattc caactcctcc accataacta
    41521 aaagttctag caagtttttt tgcagtatca aatatatctt ctatgctatc ttttggtggt
    41581 tctattacat aacaattaga atatgttact ttttttcctt ctttctgtaa tcctctattt
    41641 gctaaaattc ttccagcaaa tagaaatctt ttttgtctta ttagttttga tattcttgaa
    41701 ctattatttg aaattctctt tatccattca tcaaaactct caccattatg tctatacttg
    41761 ttcttccata ttgatttttg taattcatca aactcccaag ctttagtcct tatttcagag
    41821 cgtctttctc tatataatat gtagtgtttt gctatatctt ttctatttga ttccataagt
    41881 agtacttcaa ctatatcttg tatttcttct acggataagc atttttccat agaattatag
    41941 tcattagcta tttttcttga tatatcatat gccaactctc tatctactcc accttcacta
    42001 tttatactag ctttatagac agcatcttca atcttacttt tactaaaaag ttcttttgta
    42061 ccatctcttt ttattatgta tttcattttt aaacctccaa taaattagta ttaaattaat
    42121 acacacatta actataactc taaacaaact ttttatatat ttgtatattt tcatattaat
    42181 tatctaacat aatatatatt atactatttt atattcaata taacactcct tatagttttc
    42241 ttaacttgta aaatatcttc ctaaaaaact caaaaataat ataaaaaagt atataaaagt
    42301 caaattatac tcttatatac tttatttttt tatatttttt tcattttaac tttgattaat
    42361 taataagaat ttagaaaata aattctttat tttttcttta caaaaatatg tattgatgtt
    42421 tttatattaa tactaa
//
LOCUS       DAJMZY010000024        42358 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.024, whole genome shotgun sequence.
ACCESSION   DAJMZY010000024 DAJMZY010000000
VERSION     DAJMZY010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 42358)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42358)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42358
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.024"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            <1..828
                     /locus_tag="OE968_001264"
     CDS             <1..828
                     /locus_tag="OE968_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HCP7218552.1"
                     /translation="CKEILNEEKEIIYAYIIKIAFEEKIDLLDIFYEMEYVWIEKYLK
                     YLLALERSFNLVLYKYIISRPNTSDMEKIRVYKAISKVVLESISLSDEKYKEIFYLYI
                     MYSYKYIRYIYSNLSDFELIKFVCNDLDKFTIEFKHLLDIKNKVNNANEKLEYIHSMR
                     KLLNEYPFYNKIIKILIGELEENIKESEEFKDLKDSFIISIENMIETGKINDAKLLVD
                     DYSKTFVDDIKILNIKGILYMFENKLDKADFMLKKALSLDVENEDTIYNIEYLKSLR"
     gene            852..2729
                     /locus_tag="OE968_001265"
     CDS             852..2729
                     /locus_tag="OE968_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HCP7218553.1"
                     /translation="MNIPIVVNEKSKDIIKDWQYTCTNEDIKFTSIIILTYNQIEYTK
                     LCIESIRKFTPKNKYEIIIIDNNSSDGTVEWLKGQSDIKSVYNNKNLGFPKGCNQGIE
                     LATGENILLLNNDVIVTPNWLYNLNKALWSQDNIGAVGPITNACSYYQQIDVDYKSIE
                     DMFIFAHKINKSNINLWKYRLKLVGFCMLIKKTVLDNVGVLDELFTPGNFEDDDLSFR
                     MIESGYKLLLCQDTFIHHFGSVSFKENRNKYTDIMYINRRKFETKWGFNPEYSGMIRT
                     DLISKIDDSLEANINVLEIGCGIGATLLEIKNIYKNASIYGIEISESAGKLAKYSADV
                     LIANIEKVKLDYKKDFFDYIILGDVLEHLIDPWKIVNELKQYLKKDGYLVSSIPNIMH
                     VSVLRNLVLGNFTYEDSGILDKTHLRFFTLNEITKMFNDSNYIINSITATSMPLSEID
                     NSFIDTICKESCKEMRQQYESYQYIVKASKILDTKRYSSISMINLKYALMRIDNELDV
                     DSNLSYIFDNYNITEPCFVDDIEYLIDTFVINKATLLNRLGVEAFNRGLGDFSINMFM
                     TVLEMDRDDIDSIYNITSVLCELEEFDTAYNLIKNSSEKVQSESDIQEILCFIEGKKY
                     E"
     gene            2722..4836
                     /locus_tag="OE968_001266"
     CDS             2722..4836
                     /locus_tag="OE968_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HCP7218554.1"
                     /translation="MNNDKICFITCVNDERLYEECLVYINSLDIPKNFSIETVALRGA
                     DSIASAYNKAMRETDSKYKVYLHQDTFIINKNFIHDILEIFKKNTDVGMIGVAGVKDM
                     PVNGIWWDSDKKAGKVYDSHTGKMDIYEFSNFEECFNEVMAIDGLIMITQYDVFWRED
                     KFDGWHFYDLSQSMEFRQNKYKVIVPKQNKPWCMHDSGVVNINNGYDEYRIKFVKEYI
                     NLDLYRENFYEFDKKKASTILKSNKHVMDCMKEELTEQLRLKNYKDVLGIVSKIAHFS
                     VFNHTGLYSCEECERALLECANNLPEIENTKLFTKKDLKRRKVLHVLSEGYSTGGHTR
                     LVKNWIEIDKDSVHSVVTTWQSDTLPDWLLKAINDSGGEVISLDLISDDYLKRAVALR
                     KIAYDWADIVILYVHMWDTIPVVAFGVDGKIPILHVNHYDSTFWLGTSIADIVIDFSE
                     TSQLITLDKRGIDKSEILPMPLKEKEVFSKSEVRKRYNLEDDVTIILTIASERKYNSV
                     NDINYFKIAKTLIENTDNTIIIVVGVDTENLYWKTLSNVTDNRVICFGTTANIDDFYK
                     ISDIYLESFMVGSHTSKLDAILYDLIPVKFKNEVSPIFTNMWNFIDKFDYKNIKEVID
                     MIRRYNTSEFDRDKIKAKQSEIKHFVIDKHCIEIKNYIDKIYNEVNHHKVKYDLYKND
                     EIEDYQLFVALYGYMVKNKNMS"
     gene            4845..5840
                     /locus_tag="OE968_001267"
     CDS             4845..5840
                     /locus_tag="OE968_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation glycyltransferase
                     FemA/FemB family protein"
                     /protein_id="HCP7218555.1"
                     /translation="MNNIHINKFEKSCEKNWDYFVENKSINGTFLQTRNFLNYHEEGK
                     FTDHSLIICKGEEILAVVPACETYEDGERIFFSHLGSTFGGIIIRSGFNDIRHVNAIT
                     NKLEIYLQEQNFDKVYLKNTSRIFCKEDTSLLEYFLFKNNYMFYDELSMFLELSKYKE
                     DILANFKYSKRRDFKYSLKNNLTFKRLYSDEDIVCFFNLLSNCLDSKGAKVIHSVEEL
                     LEFKNNRLKDIVEFYAVYIDDIMICGSMVFNFQERVYHTQYLASNSTYNKYYPMIFLY
                     YNLIKDALERNFKYLSFGISTLNRGKYLDEGLATFKEGFGSSAICNRTYYKNINK"
     gene            5932..7164
                     /locus_tag="OE968_001268"
     CDS             5932..7164
                     /locus_tag="OE968_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HCP7218556.1"
                     /translation="MKRLMILGSIKYFENIVMSAKREGIYTIVCDNRIDTPAKKICDE
                     AIDVDVFDFDKIKNIAIDKKIDGILTGFTDSLMKPYVYIANELNLPCVISCNQLESVT
                     NKAVMKNYFKNNGIPTTDYCIIESLKDLEKIQGLNFPLVIKPVDGYGSRGVYFVSNIE
                     ELIEKFEYSKEASQDGQVIIEEFYESEEIQGLAWVHNGESHVFYIGDRELVNIHTGRA
                     GKPDRLIYPSKYCFQYEEEIKSIYQNITQAFGIKNGPLYVQMLVGAYGIKVSEVMPRL
                     PGGCDYMAISQITDLDIGSLFANFSVNNEVNFDEIKKYNMHLSKCVYALPIYIRPGTI
                     KKINNIDKIENLDYVTQFLLLVKEGDTIGLYEDERQDCGRVYGVANNVFDANIKKKCI
                     HEMIEILDENNENMIENF"
     gene            7184..8128
                     /locus_tag="OE968_001269"
     CDS             7184..8128
                     /locus_tag="OE968_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase"
                     /protein_id="HCP7218557.1"
                     /translation="MKLITHEQIMSLNISQKQGYEWIKESFLTKKDCQLPPKISMVEE
                     GHVFYNVMPSLNHNHKIGGIKMVTRLPGRNPSLNSEIFLYNMEDAKLKAILDGNYITA
                     FRTAAVAALAIDTFAKKDFNTIAIMGLGVTASAIMNMLSYTLKDKNINIKLLKYKDQA
                     ESFVKKYEKNEQFSFEICDTHEELIVDSDVVISTVTYTDEYLSEFKWFKKGALLLPVH
                     VMGFGNVDYLFDKVYLDDYNHLKHLENIDRYKYSCEFYDVLSKQAKGRENDDERIISY
                     NIGLSIHDILFANKIYELCETLSCEEIELKEPKEKYWI"
     gene            8222..8629
                     /locus_tag="OE968_001270"
     CDS             8222..8629
                     /locus_tag="OE968_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxcM-like domain-containing protein"
                     /protein_id="HCP7218558.1"
                     /translation="MDKYNLIRFVSIGNEYIGNLVALESNKAIPFDIKRVYYIYDVPN
                     NVKRGFHAHKNLEQVLVCLNGSVKIKCYDGVKETIFNLHKNDVGLYIGTGVWHEMFDF
                     DEKTVLISIASEHYNEEDYIRDYKEFLKYLNNV"
     gene            8716..9807
                     /locus_tag="OE968_001271"
     CDS             8716..9807
                     /locus_tag="OE968_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS family aminotransferase"
                     /protein_id="HCP7218559.1"
                     /translation="MLVKFNNLLKQFQTHKEEYEQKIKDVMESGYYILGNEVKHFEEE
                     FANYVGSKYCVGLASGLDALIIAFRALGISKGDEVIVQSNTYIASVMGISINGATPVF
                     VEPNEYYNIDSSKIEEKINSKTKAILVVHLYGQASNMKDIQELCDKYNLYLIEDCAQS
                     HGAKYDGKMTGTFGDIGCFSFYPSKNLGAFGDAGAIVTSNEEIADKVKILRNYGSEKR
                     YYNKFVGYNSRLDEIQAGLLRVKLKYLNEIEIEKSKIVDRYLNEINNPKVILPKIENN
                     CTHVWHLFVLQVEKRDTFMEYLKKSGIESIIHYPIPPHLSEAYAYLGYKKGSFNIAEN
                     YSDKVVSIPLFIGMEDEEVSYIIKIINEY"
     regulatory      10116..10206
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            10615..10932
                     /gene="flgB"
                     /locus_tag="OE968_001272"
     CDS             10615..10932
                     /gene="flgB"
                     /locus_tag="OE968_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgB"
                     /protein_id="HCP7218560.1"
                     /translation="MNTYDIIKMGLDATNLRSQTIANNIANINTEGYKRHYITFEETL
                     NDAMPKIEEKTDNSKGLRVDGNNVDIEEEKVNQAMATLQYNALISFANGKIAMTKSII
                     SGR"
     gene            10940..11344
                     /gene="flgC"
                     /locus_tag="OE968_001273"
     CDS             10940..11344
                     /gene="flgC"
                     /locus_tag="OE968_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgC"
                     /protein_id="HCP7218561.1"
                     /translation="MSVFSGMRISASGLTAESLKMDIISSNVANINATRGPNGEAYRR
                     KVVSFEENYDNKLGMLGVKVTSVEDDKSPLKEVYDPSHPDAKPNGYVEYPNVNILVEM
                     TDLITASRAYDSNVDTLNAQKSMISKALEIGK"
     gene            11354..11671
                     /gene="fliE"
                     /locus_tag="OE968_001274"
     CDS             11354..11671
                     /gene="fliE"
                     /locus_tag="OE968_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-basal body complex protein FliE"
                     /protein_id="HCP7218562.1"
                     /translation="MPITQINNLMQGAKLDNLIGEAKPLTLNNKEEKKNFEDVIIDTI
                     DKVNFQQVTADDMKEKFIKGEDVSMHEVMLIGQEAQLSMQYLIEVRNKIHDAYQEMNK
                     VQI"
     gene            11696..13246
                     /gene="fliF"
                     /locus_tag="OE968_001275"
     CDS             11696..13246
                     /gene="fliF"
                     /locus_tag="OE968_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar M-ring protein FliF"
                     /protein_id="HCP7218563.1"
                     /translation="MITSFKNKIKEQVAKSRTKISSLKKGTKIALGIGVIAICLALVF
                     TAISASKNKYAVLFSELDAQDAADISAELESKKIDTKVKGSTIYVPRTEVDKLRLELA
                     PSLTGGSKGFALMDDSSSIGLTDEEFQIKKQRMIQGEIEKTIKSFPQVEDTRVHITFG
                     ESSVFEKEAVPGSAAVYLMLKPGTTLEKNQIKSVMALISGSVTNIPEKNVQVIDNKMN
                     LLSEGILEDENVDENNQPINSGISVDKNKASEQALNKQLEKSILEMLEPIFGKGKVKA
                     TVNADLSFDTAEKTEIKIDPDKVAIKETRSKNSSKSAANNVQGVDANMNNQGNNNGTN
                     TEDSLDESFEYETGKIETHTIVAPGELNRLTASVAIDGKIAKGVQADVEDIVNNAIGM
                     DGARGDTLSVVSMVFDPEGKKEAKQELEEIKKEGFKKNIIKAVIGVVAVIAVGAIGYL
                     IYKKRSEREDMDYEDEDYISKSDSVDRKDNPLLGDDPELTLEEAVKMYAEEKPDQVTE
                     IIKTWLNE"
     gene            13259..14329
                     /gene="fliG"
                     /locus_tag="OE968_001276"
     CDS             13259..14329
                     /gene="fliG"
                     /locus_tag="OE968_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein FliG"
                     /protein_id="HCP7218564.1"
                     /translation="MSTEITNVNAFDLSDINESDKNEKVEGEGLKKAAVLLMTLGPNV
                     SSDIIKSLPDKQVQKIGLEIANISSIASKERREILKEFVEINRAKDYVIEGGLEYARE
                     LLSNALGNVKANKLLEGISINTSTKPFKHIIKLDVKKILEILRNESAQTIAVLLAHME
                     PENGAEVLSYLDFDLQNEVAMRISSMGSISPEVIKVIESSLEDKLHSISGDDFNDYGG
                     VSTLVQILINSDRKTEKNILGTIEEQNPDLAAQIKSHIFVFEDIVKLDDISIQKVLKE
                     VTMKDLVYALKGVDDEISDAIYRNQSSRAADALKEEMEMVGVIKVTQVEASQQKIANI
                     VRKLEREGAITIVRNFGGDFVE"
     gene            14322..15053
                     /locus_tag="OE968_001277"
     CDS             14322..15053
                     /locus_tag="OE968_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar assembly protein FliH"
                     /protein_id="HCP7218565.1"
                     /translation="MNNKIIKSKKALYKGVLDLTIIDKVRVGESNVNKENDCRFRDEV
                     IKEAIESAEIKKNEILEEAKINAQNIEKQAYEKGYSQGQKNGYEDGYKESYDEYTQKA
                     KDEADFIKNQANLILLQANEKMTEYIKEKNKEIVRLAINMASSVLKKHFEDEESMSDL
                     LKQIIQDYEGSSSFIVRCNSFYKDNIEKEFELFKEETSLKSSVFVIADDSIDKGNAII
                     QKENGRIIVGIDCAMEKLKEELLGE"
     gene            15057..16376
                     /gene="fliI"
                     /locus_tag="OE968_001278"
     CDS             15057..16376
                     /gene="fliI"
                     /locus_tag="OE968_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein export ATPase FliI"
                     /protein_id="HCP7218566.1"
                     /translation="MYKTDISIDFDKINKKIENLELTISEGRVKKIIGLTVEVEGIKA
                     FVGELCVIYNQVNKPVNCEVVGFKDKEVILMALGELTLIAPGCKVISKGIPLSVMCSD
                     NLLGKVLDGLGNPIDNSDAVLGDRYNLNNEPPDPMKRKKIRNIMETGVRAIDAFTTCG
                     EGQRIGIFAGSGVGKSTTLGMIARNAKADVNVIALIGERGREVLDFIDKDLGEEGMKK
                     SVVVCATSDKAPLVRLKGALTATAIAEYFRDQGKKVILMMDSVTRFAMAQREVGVAIG
                     EPPAQKGYTPSVFAMLPKLMERTGTSDKGSITAFYTVLVDGDDFNEPIADTTRGILDG
                     HIVLSRDLANKNHYPSIDVLNSLSRLMNEIASKEDIKIASFARDMLAEYREAEDLINI
                     GAYASGTNKKIDEAIYYHEHIINFLKQGINEKSSFNETISSLRRVFE"
     gene            16407..16853
                     /gene="fliJ"
                     /locus_tag="OE968_001279"
     CDS             16407..16853
                     /gene="fliJ"
                     /locus_tag="OE968_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012815984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar export protein FliJ"
                     /protein_id="HCP7218567.1"
                     /translation="MELDKNFKFRLQKVLDLKVKDEEEIKMEFAKIQQKKIDIETNLE
                     NLESNYSKYSISKNNDSIQNQKITINYLLALNNSIMDLSEELDKSTNELEKARKQLIS
                     KQIERKSLEKLKEKKYGQYYKEENLKEQNTNDEFASMSYLRNRQVL"
     gene            16882..18087
                     /locus_tag="OE968_001280"
     CDS             16882..18087
                     /locus_tag="OE968_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-length control protein FliK"
                     /protein_id="HCP7218568.1"
                     /translation="MKIQADSYNIIKDIGDRKSSSKNKNIKNNKFEDNLYKATDHKKV
                     KDRREVSKQNISSDKPENSDNECHLDEDKSNHLEDENTYEKDCSKNNEALQQLLNLLK
                     DNYKKDKDINTILNNIEKLSISDELKQELKLNKNILNKIANQNSELNKANINNSNDIE
                     NLDIVKLRELLEDNANKDIEVITKTTENDTKNIDLYSFDSNRMDNLNSNKQKDDSSDI
                     LEKLAGVNGNKSGNFGQVINKNVDMNKIKNDNVNLKQIESNVMDDSIKAIKHMKTNDI
                     QELTIKLRPKELGDMNIQLLKDGESMRAVVTVFNKDVFDSINKNIADLKQHLELTNVN
                     IKDVSVQMHSDNTNTSDTFDKAFEQQNRQNNQENMSKKNTNDKHNNVVIEDDIKENTI
                     DDDRVDLLA"
     gene            18105..18713
                     /locus_tag="OE968_001281"
     CDS             18105..18713
                     /locus_tag="OE968_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FlgD"
                     /protein_id="HCP7218569.1"
                     /translation="MYGIATALAGTQGNYRSNNLSQLERNINDIANKQVRSKGNQTVT
                     DNGTPIIGQGDDADKDLFMKILVAQMGNQDPMNPQDPTEYVSQLAQFATLEKMSAMNE
                     KLDVLLALSNSTLINSALSMATSLIGKEVEVSGEEKEDENIVGVVKSTYIKDGEVHLE
                     LEVDGSDKTVGVKYEKLLKIGEVDENSGEENDSSEHESPEEA"
     gene            18740..19723
                     /locus_tag="OE968_001282"
     CDS             18740..19723
                     /locus_tag="OE968_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-basal body complex protein"
                     /protein_id="HCP7218570.1"
                     /translation="MIKAMYSGVSGMKANQTKLDVIGNNVANAGTTSFKKSSARITDS
                     FYQTVLYASAPTAALGGTNLGQVGVGSKISSINKDMVQGNVQPTNRPSDLMIDGDGYL
                     PVVRQGTVMYTRDGSFNLDTGFKAADGALKNIKGGRLVNGDGYMLQGMIYDGEYKADT
                     GEFVKKGDAKGKEPIVIPLQSISPKDGTVQNVLEYNISKDGTVEFLLSDGQRTQFVYD
                     IPDGAKVGDTPAGIDKLKGTIQKVQTYAFQNPAGLDAEGGNLFKPSANSGDPQIAGAT
                     GTIIQGAIEASNVDIAEEFTEMIIASRSFQANSKIISTSDEILQEIINLKR"
     gene            19736..19939
                     /locus_tag="OE968_001283"
     CDS             19736..19939
                     /locus_tag="OE968_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar FlbD family protein"
                     /protein_id="HCP7218571.1"
                     /translation="MIRVTDLNGRKYILNSDLIVRIDSVPESRILLTTGEKNLVKESV
                     DEIVDKVIKYKRKINVGYIRSEK"
     gene            19939..20757
                     /locus_tag="OE968_001284"
     CDS             19939..20757
                     /locus_tag="OE968_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MotA/TolQ/ExbB proton channel family protein"
                     /protein_id="HCP7218572.1"
                     /translation="MKKTDSLTFIGLIVSTVLVLVGAAKGSSSGLKNFFDVSSILITV
                     LGSFGALMITFTIDDIKLIKNALQYSFKTMSVSKLDLLEQFKTLSKKARKEGLLSIES
                     DVMGIEDPFMKKGLELCIDGLEINEIRSILELEIDSVEDTNNRYSKLFKTWGTFAPAF
                     GMLGTLIGLIQMLADLTSPDLIASGMGKALITTFYGSLLANIALNPIAYNIDEKTEKE
                     IYVKEMMLEGIISIQSGESSIVVEERLATYLSNNEKLEIMKSNKNTERAMSNGA"
     gene            20747..21442
                     /locus_tag="OE968_001285"
     CDS             20747..21442
                     /locus_tag="OE968_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HCP7218573.1"
                     /translation="MARKKNKKKDEINPDAWLATYADTITLILTFFVLLYATSVVDME
                     KFKNIADALKGQFSGTSIFSTGSSTSEKSPIDSVLVDKNDKSNLEQDLKDKVNNSNLQ
                     NSVTVKDDSRGILLELDDSILFDSGISELKVDSKATLNKVYDMIKMMKNKIVIEGHTD
                     NVPVKSSTHESNWDLSSSRAVSVVRYFVEEKGMDPRLFSATGCGEYQPLVSNETAKGR
                     AENRRVNILITID"
     gene            21454..21897
                     /locus_tag="OE968_001286"
     CDS             21454..21897
                     /locus_tag="OE968_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body-associated FliL family
                     protein"
                     /protein_id="HCP7218574.1"
                     /translation="MFKNKKIIIIILILIIFSAGAGFFILGEGGNKQVDKIADLFIPT
                     GKGKDEVKTENLDLEEMVLKLADEGVRYLKVSITVSYDSSYKDIEKNTPLIRDNIINC
                     FMAKRADDFTADNLKNIKEEIKNTLNIQLGENVIQNIYFTNIVVQ"
     gene            21912..22286
                     /locus_tag="OE968_001287"
     CDS             21912..22286
                     /locus_tag="OE968_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FliZ"
                     /protein_id="HCP7218575.1"
                     /translation="MILYLLKILICIPIILILIVLSLKISQGTLLKKYNDKYVKILDI
                     VNISKNNSIIILKIGEEGCIMASSSSSMSKIKDLTKEEILKIENDIKERNFKIQDFKM
                     ERIKKKYDFSRYIGKFTKKEDK"
     gene            22287..22952
                     /gene="fliP"
                     /locus_tag="OE968_001288"
     CDS             22287..22952
                     /gene="fliP"
                     /locus_tag="OE968_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425215.1"
                     /note="The bacterial flagellar biogenesis protein FliP
                     forms a type III secretion system (T3SS)-type pore
                     required for flagellar assembly; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar type III secretion system pore protein
                     FliP"
                     /protein_id="HCP7218576.1"
                     /translation="MELLSKLPLADVPYTSSMQLFLFLTALMFLPFVMFMMTSFVRIV
                     ISLSFLKSALGAQQAIPSQILVGLAIVLTIFIMRPVLNEINEKALQPYMKEEVTMEEA
                     MKEAEGPIKEFLLTQTRQTDLDLFVEQAGLKEKKLTRENIPLSVVVPAFAISELKTAF
                     QIGFLIYIPFLIIDLVVASVLMSMGMFMLPPVMISLPFKLLLFVMVDGWNLIVKTLIL
                     GFG"
     gene            22965..23234
                     /gene="fliQ"
                     /locus_tag="OE968_001289"
     CDS             22965..23234
                     /gene="fliQ"
                     /locus_tag="OE968_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FliQ"
                     /protein_id="HCP7218577.1"
                     /translation="MSEFMIMSVLKNGMFTGAMIAAPVLIVSLVVGLLISVFQATTQI
                     QEQTLTFVPKLIAILLVVAIGGSWMLHTLISFTSEIFNMISLITK"
     gene            23246..25060
                     /locus_tag="OE968_001290"
     CDS             23246..25060
                     /locus_tag="OE968_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fused FliR family export protein/FlhB family
                     type III secretion system protein"
                     /protein_id="HCP7218578.1"
                     /translation="MIFVFIRIVAFFGTLRILFPAGTPALFKSLFAIIISILISSTMQ
                     IEYATNIDNIVLFTLYGVNETITGIMLGYITNLCFYSIRMAGSMMDQQMGLSMINMFD
                     PNSMTQTTLIDNLMNWTALMIFFSMDGHHVLIRGIRYSFELIPIGKPFVDNNIDYIIN
                     IFVQCFLTGFKIAIPIVLCLLMADFILGLISRSVPQLNVMIVGMPLKILVGIALFIIS
                     IPLIVNQISHLLSQIPKMYEGTFALAPMFFMGSADKTEEATPKKKGEQRKKGNIAKSR
                     ELPVAMTLLAFTLLVPTLFSYVVDTLKSSLNYFLSLDFYMNINYSNLEKLVIAGLMDF
                     FKIFLPIAIPFLVLGIIANLFQVGILFTGETLKPNLSKLNPISGFKNMFSMRSLSTLI
                     KDTAIISILAYIGYTFFQDNYLDILKLGNIYLPTLMYTVKDLVYSILSKICVAMIAIA
                     VADYVYQRYSHKKQLRMTKQEVKDEYKNSEGDPEVKAKIKQKQRQISSQRTMQAVPSA
                     TVIVTNPTHLSIAVRYEKGKDQAPVVVAKGADYLAFKIREIAKGNNIPIIENKPIARL
                     LYKQVEIDQEIPEDMYQAFAEILVAVYKIKNRYKVPKR"
     gene            25069..27144
                     /gene="flhA"
                     /locus_tag="OE968_001291"
     CDS             25069..27144
                     /gene="flhA"
                     /locus_tag="OE968_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FlhA"
                     /protein_id="HCP7218579.1"
                     /translation="MNKFNLKENMDVIVAFGVVGIVLMMIVPLPTFILDILLAINISL
                     SVLILLMTLFTTNVLDLSIFPTVLLVTTLFRLGLNLSSTRLILTQGYAGEVIEAFGSF
                     VVGGNYVVGIIIFLIILIVQFVVITNGSGRVSEVTARFTLDAMPGKQMSIDADLNAGV
                     IDDKTARKRRKELQQEADFYGSMDGANKFVKGDAIAGLIVTAINIIGGIVIGAVMLNM
                     TLMGAAQTYVRLTIGDGLVSQIPALLISTSAGIIVTRASTDENFGDLVGKQLTAIPKA
                     VMMTGCVLIVLGMMPGLPKPAFFSLGIGAIAAGYFLGREKKDTLEDLEFEKPDMVNPD
                     KNEVEDVTNLINVESIEVEIGYGLISLADESAGGDLLQRIASIRRQCAIDMGIVVQPI
                     RIRDNLQLNPNQYNIKIKGNVVGGYEIMPNMVLCMDPMNQGFSIFGIKTIEPTFGIEA
                     LWIESDKVEDAELKGYTVVDSSTILITHLLDIIKSNAHELLGRQEVKTIIDAARENYS
                     AVVDELIPDLMTLGEIQKVLKNLLREKVNIKDRVTILETLADQSRNTKDIELLTEYVR
                     IALARSICNNLVDDDKTIVVATLSPETEELVSNNLQRSVNGTYPAVDPENTNKIFESI
                     QEVMSNVYFNHNIPVIVVSPKIRAPFRKLVEIVYPNLTVLSLNEIPNDIKIKAEGVVS
                     IYDDEKVYS"
     gene            27119..28135
                     /gene="flhF"
                     /locus_tag="OE968_001292"
     CDS             27119..28135
                     /gene="flhF"
                     /locus_tag="OE968_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FlhF"
                     /protein_id="HCP7218580.1"
                     /translation="MMTKKYTANTIQDAMNLAKMELGDNITLIDKKEVRKSGIQGIFS
                     KKDIELTIGWEKRENVEQKDLKREIEQLKSIINNMGFDNKNDNDIDKICKNLLSLELN
                     EEIVESIRIDLQEMKFNGIDTSKNLVEILKKKIKIENQVINGKIALVGPPGVGKTTTI
                     AKLAAKLVFEENKKVGVITIDTYRIGAVEQLKIYTDIMNIPFKGVISPDEMELALDEM
                     KDCDVVLIDTTGRGYKNSMQILEIKNLIDKAETDNIHLVLNCTTRESDTKAIIDSYRN
                     VNFKSLIITKLDETITYGSIFNIMNYAQKPISYITTGQNVPDDIIKPNEDKIIRLLLG
                     VESI"
     gene            28132..29010
                     /locus_tag="OE968_001293"
     CDS             28132..29010
                     /locus_tag="OE968_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MinD/ParA family protein"
                     /protein_id="HCP7218581.1"
                     /translation="MIDQAQILRKIAMEKRGLDEFIVENENVPKIITIASGKGGVGKS
                     NLATNLSICLTKLNKKVLILDADIGMSNIDIIMGVNVKGTIIDVINGEKNIEDIISQT
                     KYGVNIISGGSALNHIEDFTEAQRNKFIHSIEQIHDVDFIIIDTGAGMSKSLLSFIYC
                     STEFFLITTPEPTSLTDAYSLLKAISNFGIKRSANIIINRVIDLEEAKSTYKRIKMVV
                     DKFLNLNLELYGYIIDDKKVSLCVKKQIPFILEYPTSIASKCIIAIAKRMVSQSREDI
                     VDNKSFLRKMFSIFKS"
     gene            29024..29725
                     /locus_tag="OE968_001294"
     CDS             29024..29725
                     /locus_tag="OE968_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliA/WhiG family RNA polymerase sigma factor"
                     /protein_id="HCP7218582.1"
                     /translation="MNREELIKENMPLVKSIARKFFIPGKGFEYQDLVNSGVIGLIDA
                     INKFDAEKGAKFSSYSYIKIKSAILDEIRNQSPISKHNLTKVNKYNRVVEKLQSKLLR
                     EPTSYEIAKELKVSEKELHDIESNIDMLNIVSLNYVIFEDTNETVQDVISDREEEAPE
                     NIIEEEEKLEILSKAISNLNEREKLILSLYYYEDLNLKEIGKVLGVSESRVSQLHRKS
                     IRNLRNKIKELKYSI"
     gene            29741..30163
                     /locus_tag="OE968_001295"
     CDS             29741..30163
                     /locus_tag="OE968_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein"
                     /protein_id="HCP7218583.1"
                     /translation="MIQIILIVVSILIIVTIVINLHKESKNKDNRYFDKIFEQEYEAN
                     DRLIIAEKRRFFLDKVLAEKRINSHIKVYENYNLIKANEERKENIFIESKKEVRQENE
                     LSLKVKHLISSGYDDVEICKMLDIGKGELLLIRSCYKI"
     gene            30148..30333
                     /locus_tag="OE968_001296"
     CDS             30148..30333
                     /locus_tag="OE968_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein"
                     /protein_id="HCP7218584.1"
                     /translation="MLQNIRILLCDKKVFLGIGIGILISTLCIMLFSNNDMSKAEIEK
                     KARALGMKYTSEMKVLE"
     gene            30374..31147
                     /gene="flgG"
                     /locus_tag="OE968_001297"
     CDS             30374..31147
                     /gene="flgG"
                     /locus_tag="OE968_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgG"
                     /protein_id="HCP7218585.1"
                     /translation="MIRGLYTAVSAMITNQQKQNVVVNNLANMDTNGYKSKQLLTKSF
                     DELKLEGYNNYANGTKQKQIIGDISPGISMDETITNFNQGPIKTTDNKMDVAIQGKGF
                     FLVSDAAGNQFYTRNGNFRTDNQGDLITSEGYYVLGTNTATGAVGHINVGNQKFEVAK
                     DNTISLDGNAMYKFNIVDFNNYNNLKKEGDNLYSGGGAMKVNNALTIQSAIESSNVDM
                     VSEINNMMTISREYEANQKIIQAMDSKLAKIASEIGSVR"
     gene            31168..31929
                     /gene="flgG"
                     /locus_tag="OE968_001298"
     CDS             31168..31929
                     /gene="flgG"
                     /locus_tag="OE968_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgG"
                     /protein_id="HCP7218586.1"
                     /translation="MYTMFYTSKTALSANQSKLDIISNNIANSDSTGYKKINMEYSDL
                     VDEVLNRPSYPTNGNDISTGTGAKATAPMRNYEQGALAPTDSKSNLAIDGEGFFRVIR
                     KDGTYAYTRNGGFNVDALGKIVDDNGNILDVQFDAGYNYNNTNIDSTNLTVSRNGELF
                     VDNKKIGKINLYQPIGTQNFISEGDSLFVATDAAQIKQVEKVDIVQGYRERSNVSLQE
                     EFVDLIATQRAFQMNSKGIKTADEMWQIANNLRAK"
     gene            31952..32833
                     /locus_tag="OE968_001299"
     CDS             31952..32833
                     /locus_tag="OE968_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliM/FliN family flagellar motor switch protein"
                     /protein_id="HCP7218587.1"
                     /translation="MNDMKEYDFGKPQSYSRENLTCLNFLLAEFCKKYKNYIIYELKC
                     NSSMVVDSIDQVNYQTFLDRVTSSCVVVQNAMEPVMKNFSFRIDRSVADMWIDITSGG
                     TGVVKDNDRELTELDKKVLLHLMDDLVRNMHLFEGFENIQVLDTHTHINLPQLCSPTA
                     PVCVVDLKVLNDNEYIGSVSLCFPYNGLEALLESISVIEFFDNDVGDDSEEFTQKIYN
                     SVSNIELSVIAEIGKVSINVEDLLKLEVGDVIVTNKKINDYIDIFVENSKSYTATPGF
                     ISSKKGVKINDAVGKEV"
     gene            32836..33210
                     /locus_tag="OE968_001300"
     CDS             32836..33210
                     /locus_tag="OE968_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliM/FliN family flagellar motor switch protein"
                     /protein_id="HCP7218588.1"
                     /translation="MDNSNLISDEEAKMLLNDKVESEVDGDDELALDVSEVNRNNIQR
                     ILDLKLELSVVIGRTKMTLRDILNLHKGSLIELDTLADQDVEILIDNKVLAYGKVVVV
                     DLNFGVKITSIVSEEDMVKSLV"
     gene            33242..34645
                     /locus_tag="OE968_001301"
     CDS             33242..34645
                     /locus_tag="OE968_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HCP7218589.1"
                     /translation="MVLILNLNDIKKDILKLNKKDSCSLYNESINNINNNCISTGLKF
                     LKQARDLNPDDVDILNLTGLVNLLKCNFDDAVESFYKSSLCEKTALCEKYINMLTSEE
                     FLIFFEKYNQLIRLINKGMYKEAIQGFKLITDQYCDLIEPYELLALLYDKEEEYIKFD
                     ECLEVLKIIDKENYLLNQENNTLYMYNSANIQTKSNIKVDDYKNEFLHKSSSNHKIND
                     YNDVTKEKSSSKNQKSSDSNKKKSIKKNKYLYIAIILGILLVGQSIYSSYKMNNLTDK
                     ISKNNETKNEESIDSNLTKKENNIEENEDMSKASNINKSNKNINKEDDVKSKKNTVEN
                     EDDKDSDLFTEDELMSKANTLKSEKKTKSSIQLYKKVADIGENKGNTSEATYQVAILS
                     EKLKDYKTAEEYYKMYVENYSEKDAYFDESYYNLGMMYYNNGDLKNSKLTLKKLVNKV
                     PNSMYNNSKVKEILKEE"
     gene            34761..36698
                     /gene="htpG"
                     /locus_tag="OE968_001302"
     CDS             34761..36698
                     /gene="htpG"
                     /locus_tag="OE968_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone HtpG"
                     /protein_id="HCP7218590.1"
                     /translation="MEFEKGSISIHTENIFPIIKKWLYSDKDIFIRELISNGCDAVSK
                     HKRLVSLGEISENKSSDYKITVSVNKGEGTLKFIDNGIGMTEEEIKKYINQVAFSGAE
                     DFFNKYKDKMEESNDIIGHFGLGFYSAFMVSKKVQIDTLSYTEGATPVRWISEGGTEY
                     EISESDARNDRGTTITLFIDDDSKEFLDEFTVRGIINKYCSFLPVEIYLEDVERLERE
                     AKEAEEKAKKQKEDGKEEIVDAKVIEPLNDTNPLWLKSPKDCTDEEYKEFYRKVFNVF
                     DEPLFWIHLNVDYPFNLKGILYFPKLKNEFELTEGKVKLYNNQVFVADNIKEVIPEFL
                     LLLKGVIDCPDLPLNVSRSFLQNDRDVSKISKHIIKKVADKLKSLCKNEREEYNKFWD
                     DIQIFIKYGCLKDESFYEKVKECILFKTIDDEYITLQDYLEKCKDKHENKVFYVSDKE
                     QQSQYIKLFKEYDLSAVVLNSSIDTHFISFMEYKENGVKFNRIDADLSDVLKDKNENK
                     DSEENKEEIAKIEGLFKEAVGERVKNYSVEGLKNEDTPAMVLVSEQSIRMAEMQSRFA
                     GMDLGMNFEEEKTLVINENSPIIKKLVSLKDDEEKKDKITLICNQIADLALLSNKELK
                     PDELDSFVQRSNKLMSLLIEL"
     gene            37085..38215
                     /locus_tag="OE968_001303"
     CDS             37085..38215
                     /locus_tag="OE968_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HCP7218591.1"
                     /translation="MNFNYNLPVNILFGRGRINDVGKEVSKYGKKVLIVTGKNSTKKT
                     GLLDKTIDLLKDSKIEYEVFDRVEQNPLITTIYSGVEIIKSTGCDCVLGLGGGSIMDA
                     AKSIAFSYKNPGDLNDYIFGIRQGEEALPIILVPTTSGTGSEGNCFAVLTNSETKDKK
                     SIKKNSMYAKASIIDPELMVTMPKHIIASVGFDALAHNMEAYLSNGRNPLADVQAIYG
                     IELISENLIKVYNDVNDLEAWEKITLASTIGGMTIGTAGTALPHGMEHPVSGLRDVMH
                     GKGLAALTPTIIESSWDSDIERFGNISKVLGGTCAEDCSDAIRNFLKKIDLDIKLSDL
                     GIEKSDIDWLTDNCMKISVANIKRHPKYFNKEQIKEMYHKSL"
     gene            38442..39464
                     /gene="splB"
                     /locus_tag="OE968_001304"
     CDS             38442..39464
                     /gene="splB"
                     /locus_tag="OE968_001304"
                     /EC_number="4.1.99.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore photoproduct lyase"
                     /protein_id="HCP7218592.1"
                     /translation="MFNPKRIIFEKGTLDTDVGKKIYNKFRDNKDVEIINISSNRIKE
                     HIPGENLYEQYRSGKQTMVVGIRKSLKFQTCKPSANYQLPLVSGCMGRCEYCYLNTQL
                     GDKPFIRVFVNVDEILEQTKKYIEDRKPQVTIFEGAATSDPVPVEPYTNSLKKTIEFF
                     GREEKGRFRFVTKYSDVDSLLDAEHNNHTEIRFSINTPRIINEHEHYTASANKRIESA
                     VKLARAGYQIGFIIAPVFLYEGWKEEYKNLIISIKEALPKDFDKKIIFEVISHRYTTK
                     AKNRILEIYPDTLLPMENEDRKFKYGQFGYGKYVYDKEQLDDMKEFFLKEINGVFKNS
                     LIKYII"
     gene            39646..40557
                     /locus_tag="OE968_001305"
     CDS             39646..40557
                     /locus_tag="OE968_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HCP7218593.1"
                     /translation="MHAWESIQITLDLIEANLSEEISINELANKANLSPFYYQRLFKR
                     LVNKTVMEYIKLRRLARASEYLAEHKNRILDVALNFGFASHETFTRSFKKAYGLTPEK
                     YRANPVKLNHFIKPELILNYAMVDEGVPLIADDIVIEVNRKTLSNPRTFVGIEIEVPI
                     CQLVGGETTGIAIVEELWMKLGSQRHNIPNQIPGGNEFAALYMGNAKEGNCMYMAGVE
                     VESGTSVEGYSTFELPAKEYLVCGFEAENFNELVNSAVFKADKFMERWMKKHNLTTTD
                     FAIEMYYPTTPEAAYLEHWIVPVPIEQ"
     gene            40572..40988
                     /locus_tag="OE968_001306"
     CDS             40572..40988
                     /locus_tag="OE968_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3788 domain-containing protein"
                     /protein_id="HCP7218594.1"
                     /translation="MNWQDAFFQDTKPTFEQINEFINNPLWDKLNKTLVSTYNVEPKL
                     EYSKCSMQRGWNVKYKKRGKSLCTLYPQEGYFKALVIVSESNRVEVDLFINTCCDYIK
                     KIYNEVNFFNGSKWLMIQVDSLLVLNDMLELIKFRA"
     gene            complement(41088..41480)
                     /locus_tag="OE968_001307"
     CDS             complement(41088..41480)
                     /locus_tag="OE968_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCP7218595.1"
                     /translation="MSINTEKNITKNVEELTCPIRYALDIVGGKWKLPIICMLAVENP
                     IRYSSIKRKLDGITNTMLAQSLKDLESTGIVHRKQYNEIPPKVEYTLTSKGKSIVPIL
                     QQFANWGATNMQEKNTCGLSCKECRKIK"
     gene            41621..42016
                     /locus_tag="OE968_001308"
     CDS             41621..42016
                     /locus_tag="OE968_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HCP7218596.1"
                     /translation="MKALEFLNKARVYYLATVDENNQAHVRPLGFVMEYNGKLTFCTS
                     NQKDMFKQLIFNPKVELCCIDQNLNTLRILGEAVFVTSKETQAKALEIMPSLGQMYSV
                     GDGKFEIFSIDKAKVSCCSMSGKKIDVEL"
BASE COUNT        17338 a         4283 c         7657 g        13080 t
ORIGIN      
        1 tgtaaagaaa tactcaatga agaaaaggaa ataatttatg catatattat aaaaatagct
       61 tttgaagaga agattgattt actagatatt ttttatgaaa tggaatatgt atggatagag
      121 aaatatctaa aatatctttt agcattagaa agaagtttta atttagtact atataagtac
      181 ataattagtc gtccaaatac atcagatatg gaaaagataa gagtatataa agctatatct
      241 aaagtagttt tagaaagtat aagcttaagt gatgaaaaat ataaggagat tttttatctt
      301 tatataatgt attcttataa gtacataaga tacatatata gcaatttaag tgattttgaa
      361 ttaataaaat ttgtttgtaa tgatttagat aagttcacta tagaatttaa gcatctactt
      421 gatattaaaa ataaagtaaa taatgctaat gaaaaattag agtatataca tagtatgagg
      481 aaattactaa atgagtatcc tttttataat aaaataataa aaatacttat aggtgaatta
      541 gaagaaaata taaaagaaag tgaagaattt aaggatttaa aagatagttt tattattagt
      601 atagaaaata tgattgaaac tggcaaaata aatgatgcga aattattggt agatgactat
      661 tcaaaaacat ttgtggatga tataaagatt ttaaatataa agggaatttt atacatgttt
      721 gaaaataagc ttgataaagc tgattttatg ttaaaaaagg cattatcatt agatgtagaa
      781 aatgaagata ctatatataa tatagaatac ttaaaaagtt taagataagt caaaaatagg
      841 agaattgaag aatgaatata ccaatagtgg ttaatgaaaa atctaaagac ataataaaag
      901 attggcaata tacatgtaca aatgaagata taaaatttac aagcataata atattgacat
      961 ataatcaaat agaatatact aaattatgta ttgaaagtat taggaaattt accccaaaga
     1021 ataaatatga aataataata attgataata actcttctga tggaacagtt gagtggttaa
     1081 agggacaatc tgatataaaa tctgtgtata ataacaaaaa cttaggattt ccaaaaggat
     1141 gcaatcaagg tattgagtta gctactggtg aaaacatatt gttgttaaat aatgatgtaa
     1201 tagttactcc aaattggctc tataatttga ataaagcttt atggtctcaa gataatatag
     1261 gtgctgtagg acctattacg aatgcatgtt catattatca gcaaattgat gttgattata
     1321 agtcaattga ggacatgttt atatttgcac acaaaataaa taaatctaat attaacctat
     1381 ggaaatatag attgaagtta gttggatttt gcatgttaat aaaaaaaact gttctggata
     1441 atgtaggggt tttagatgaa ttattcacac ctggaaattt tgaagatgat gatttatctt
     1501 ttaggatgat agagtcagga tataagttat tattatgcca ggatactttt atacaccatt
     1561 ttggaagtgt gtcttttaaa gaaaatcgta ataaatatac agatataatg tatattaata
     1621 gaagaaaatt tgaaactaag tggggattta atccagaata tagtggaatg ataagaacag
     1681 atttgatttc taaaatagat gatagtttgg aggcaaatat taatgtttta gaaataggat
     1741 gcggtatagg ggctactctt ttagaaataa aaaatatata taaaaatgca tcaatatatg
     1801 gaatagaaat tagtgagtca gcaggtaaac ttgcaaagta tagtgcagat gtacttatag
     1861 caaatataga aaaagtaaaa ttggattata aaaaagattt ttttgattat ataatattgg
     1921 gagatgtact tgaacatttg attgacccat ggaagatagt caatgaattg aaacaatatc
     1981 taaagaagga tggttatctg gtatctagta taccaaatat tatgcatgtt tctgttttaa
     2041 gaaatcttgt gttaggtaat tttacatatg aagattcagg aattttggac aagactcatt
     2101 taaggttttt tacattaaat gagataacaa aaatgtttaa tgatagtaat tacataatta
     2161 atagtattac agctactagt atgccacttt cggaaattga taatagcttc attgatacaa
     2221 tatgtaagga aagctgtaaa gaaatgagac aacagtacga atcttatcaa tatatagtaa
     2281 aagcctctaa aatcctagat actaaaagat attctagtat tagtatgatt aatttaaaat
     2341 acgctttaat gagaattgat aatgaattag atgtagatag taatttaagt tatatatttg
     2401 ataattataa tataactgaa ccatgttttg ttgatgatat tgaatatcta attgatacat
     2461 ttgtgataaa taaagcaact ctattaaata gattaggagt tgaggcattt aacagaggtc
     2521 taggagattt tagtataaac atgtttatga cagtattaga gatggataga gatgatattg
     2581 actcaatata taatataaca agtgtattat gtgaattaga agaatttgat actgcttata
     2641 atttaattaa aaatagtagc gaaaaagtac agagtgaaag tgatatacaa gagatacttt
     2701 gttttattga ggggaagaaa tatgaataat gataagatat gttttataac ctgtgtaaat
     2761 gatgaaaggc tttatgaaga atgtcttgta tatataaata gcctagacat tcctaaaaac
     2821 tttagtatag aaacagtagc tttaagagga gccgattcta ttgcctctgc ttataataaa
     2881 gctatgagag aaacagattc taagtataag gtatacttac atcaagatac ttttataatt
     2941 aataaaaatt tcatacatga tattttagag atatttaaaa aaaatacaga tgtcggaatg
     3001 attggtgtag ctggagtaaa agatatgcct gtgaatggaa tttggtggga ttctgataaa
     3061 aaagcaggga aagtatatga tagtcataca ggtaaaatgg atatttatga atttagtaac
     3121 tttgaagaat gttttaatga agttatggct atagatggat taattatgat tactcaatat
     3181 gatgtatttt ggagagagga taagtttgat gggtggcatt tttatgattt gtcacagagt
     3241 atggagttta gacaaaataa atacaaagtt attgtaccaa aacaaaataa gccttggtgt
     3301 atgcatgatt ctggagtagt aaatataaat aatggatatg atgaatatag gataaaattt
     3361 gtaaaagagt acataaatct tgatttatat agagaaaatt tttatgaatt tgataagaag
     3421 aaagcaagta ccatacttaa gagtaataag catgtaatgg attgtatgaa agaggagctt
     3481 acagaacaat taagattaaa gaattacaag gatgttttag gtattgtttc taaaattgct
     3541 catttttctg tttttaatca tactggtttg tattcttgtg aagaatgtga gagagcattg
     3601 ctagaatgtg caaataattt accagaaata gaaaatacga aattatttac aaaaaaagat
     3661 ttaaaaagaa gaaaagtatt acatgtttta agtgaaggat attcaacagg aggtcataca
     3721 agactagtta aaaattggat tgaaattgac aaagactctg ttcattcagt tgtaactaca
     3781 tggcaatcag atacactgcc agactggtta ttaaaagcaa taaatgatag tggtggcgaa
     3841 gttatatctt tggatttaat ttcagatgat tatttaaaaa gagctgtagc tttgaggaaa
     3901 atagcttatg actgggctga tatagttatt ttatatgttc atatgtggga tacaatacct
     3961 gttgttgctt ttggagttga tgggaaaata cctattttac atgttaatca ctatgatagt
     4021 actttttggt tagggacaag tattgcagat attgtcattg attttagcga aactagtcaa
     4081 ttaattacat tagataaaag aggcatagat aaatctgaaa tattaccaat gccattaaaa
     4141 gaaaaagaag tattttcaaa atctgaagtt agaaaacgat ataatttaga ggatgatgtg
     4201 acaataatat tgactattgc tagtgaaaga aaatacaata gtgtaaatga tattaattac
     4261 tttaaaattg ctaaaacatt gattgaaaat acagataata caattattat tgttgtagga
     4321 gttgatacag agaatctcta ttggaaaact ttaagtaatg ttacagataa tagagttata
     4381 tgttttggaa caacagcaaa tatagatgat ttttataaga tttcggatat atacctagag
     4441 tctttcatgg taggaagtca tacttcaaaa ttagatgcaa ttttatatga tttaattcct
     4501 gttaagttta aaaatgaagt ttcaccaatt tttacaaata tgtggaattt tatagataag
     4561 tttgattata agaatataaa agaggttata gacatgataa gaaggtacaa tactagtgaa
     4621 tttgacaggg ataagataaa agcaaaacaa tcggaaataa aacattttgt tatagataaa
     4681 cattgtattg aaataaaaaa ctatatagac aaaatatata atgaagttaa tcatcataaa
     4741 gttaagtatg atttatataa aaatgatgaa atcgaggact atcagctttt tgtagcatta
     4801 tatggctata tggtaaaaaa taaaaacatg tcataggtgg taaaatgaac aatattcata
     4861 tcaataaatt tgaaaaaagc tgtgaaaaaa actgggatta ttttgtagaa aataaatcta
     4921 taaatggtac atttctgcaa actagaaatt tccttaatta tcatgaggag ggaaaattca
     4981 ctgaccactc attaataata tgtaaaggtg aagaaatact agcagtcgta cctgcatgtg
     5041 aaacttatga agatggtgaa agaatatttt tttctcattt agggagtact tttggtggca
     5101 ttataataag aagtggtttt aatgatatta ggcatgtaaa tgccattaca aataagttag
     5161 aaatatattt acaggaacaa aatttcgata aagtatattt aaaaaataca tcaagaatat
     5221 tttgtaaaga ggatacttca ttactagaat attttttatt taagaataat tacatgtttt
     5281 atgatgaatt aagtatgttt ttagaattaa gtaagtataa agaagatata ttagccaatt
     5341 ttaaatacag taaaagaaga gattttaaat attctttgaa gaataatctt acctttaaaa
     5401 gactgtatag tgatgaagat atagtttgtt tttttaattt actttctaat tgtttagata
     5461 gtaaaggagc taaagtaata cattcagtag aagaactttt ggagtttaaa aataatagat
     5521 taaaagatat tgtagaattt tatgcagtat atattgatga cattatgatt tgtgggagca
     5581 tggtatttaa ctttcaagaa agagtttatc atactcaata tctagcatca aattcgacat
     5641 ataataaata ttatccaatg atatttttat actataatct aataaaagat gctttagaga
     5701 gaaattttaa gtatctttct tttggaatta gcactctaaa tagaggcaaa tacttagatg
     5761 agggtttagc tacatttaaa gaaggttttg gttcaagtgc aatttgtaac agaacatact
     5821 ataaaaatat aaataagtga gaatcatgtt ttatagagtt tttagagtat agtaaatatc
     5881 tagtactata atattacata aaaataatta gtttataaag aaggtttgta tatgaaaaga
     5941 ttaatgattt taggctcaat taagtatttt gagaatattg ttatgtcagc taaaagagag
     6001 ggaatataca caattgtttg tgataataga attgatactc ctgcgaaaaa gatttgtgat
     6061 gaagcaatag atgttgatgt atttgatttt gataaaataa agaatatagc tatagataaa
     6121 aagatagatg gaattttaac tggatttaca gattctttaa tgaagccata tgtttatatt
     6181 gcaaatgaac taaatttgcc atgtgtgatt tcttgcaatc aacttgaatc tgtaactaat
     6241 aaggctgtta tgaaaaatta ttttaaaaat aatggaatac ctacaactga ttattgtatt
     6301 attgaaagtt tgaaagattt agaaaaaata caaggattaa attttccact tgtaataaaa
     6361 cctgttgatg gttatggttc aagaggtgta tattttgtat caaacataga agaattaata
     6421 gaaaaatttg aatattctaa ggaagcctcg caagatggac aagtaataat tgaggaattt
     6481 tatgaaagtg aggaaataca aggactagct tgggttcata atggagagtc acatgtattt
     6541 tatattggag atagagagct tgtaaatata catacaggaa gagctggaaa accagataga
     6601 ttaatttatc catcaaagta ttgttttcaa tatgaagaag aaataaaatc catatatcaa
     6661 aatataacgc aggcttttgg cataaaaaat ggacctcttt atgtacaaat gttagtggga
     6721 gcatatggaa taaaggtatc tgaagtaatg ccaagattac ctggaggttg tgactatatg
     6781 gctatttctc aaataacaga tttagacata ggaagtttat ttgcaaactt tagtgtgaat
     6841 aatgaagtaa attttgatga aataaagaaa tataatatgc atctatcaaa atgtgtatat
     6901 gcattaccaa tatacataag acctggcaca ataaaaaaga taaataatat agataaaata
     6961 gaaaacttag attatgtcac tcaatttcta ttactagtaa aagaaggaga tacaatagga
     7021 ttatatgaag atgagagaca ggattgtgga agagtttatg gagtagcaaa taatgtattt
     7081 gatgcaaata taaagaagaa atgtattcat gaaatgatag aaatacttga tgaaaataat
     7141 gaaaatatga tagaaaattt ttaaataagg gagtatgata gatatgaagc taataactca
     7201 tgaacaaatt atgtcattaa acatttctca gaaacaagga tacgagtgga taaaagaatc
     7261 ctttttaaca aaaaaagatt gtcaattacc accaaaaata agcatggtag aagaagggca
     7321 tgtattttac aatgtaatgc cgtccctaaa tcataatcat aagattggtg gaataaaaat
     7381 ggttacaaga ttgccaggga gaaatccaag tttaaattca gagatatttc tatataatat
     7441 ggaagatgct aaattaaagg ctattttaga tggcaattat attacagctt ttaggactgc
     7501 tgctgttgct gccttggcta tcgatacatt tgctaaaaaa gattttaata ctattgctat
     7561 tatgggttta ggtgtaactg cttctgctat aatgaatatg ctttcatata ctcttaaaga
     7621 taaaaatata aatataaagt tacttaaata taaagaccaa gcagagtcgt ttgtaaaaaa
     7681 gtatgaaaaa aatgaacaat ttagttttga aatatgtgac acacatgaag aacttattgt
     7741 agattcagat gtagttattt ctactgtgac atatacagat gaatatttat cagaatttaa
     7801 atggtttaaa aaaggtgctt tattattacc tgtacatgtt atgggatttg gaaatgttga
     7861 ttatctattt gataaagtat atttggatga ttataatcat ttgaaacatc tagaaaatat
     7921 agatagatat aaatattctt gtgaatttta tgatgtttta agtaaacaag ctaaaggaag
     7981 agaaaatgat gatgagagaa taatatctta caatataggt ttgtcaatac atgatatatt
     8041 atttgcaaat aaaatttacg aattgtgtga aacactaagc tgtgaagaaa tagaattaaa
     8101 agaaccaaaa gaaaaatatt ggatatagtt tatttcattc atatttacaa tagtttattg
     8161 taaatatgaa tatgaagtaa tatattgtta gaaaattagc atgaatagga tagataaatt
     8221 tatggataaa tataatttaa ttaggttcgt atctattgga aacgaatata taggaaattt
     8281 agttgcatta gaatcaaata aagcaatacc ttttgatata aagagagttt attacatata
     8341 tgatgtacca aacaatgtaa agagaggatt tcatgcacac aaaaacttgg aacaagtact
     8401 agtttgccta aatggaagtg tgaagataaa atgttatgat ggtgtaaaag agactatatt
     8461 taatttacat aaaaatgatg ttggattata tataggaacg ggagtgtggc atgagatgtt
     8521 tgattttgat gaaaaaactg ttttaatttc tatagcatct gaacattata atgaagaaga
     8581 ttatattaga gactataaag aatttttaaa gtatttaaat aatgtgtagt tattatacaa
     8641 ttagtgatgt attttcttaa ttaaataaat ttaagatagc cacatagaga atagatagat
     8701 taggatgtga atttattgtt ggttaaattt aataatttat taaaacagtt ccaaactcat
     8761 aaagaagaat atgaacagaa gattaaggat gtaatggaaa gtggatatta tatccttgga
     8821 aatgaagtaa agcattttga agaagaattt gctaactatg taggtagcaa atattgtgtt
     8881 ggtttagcca gtggtttaga tgcactgata attgctttta gagcattagg aataagcaaa
     8941 ggtgatgaag taatcgtgca atcaaataca tatattgcta gtgttatggg aatcagtata
     9001 aatggagcaa caccagtatt tgtagaacca aatgaatatt ataatataga ttcatctaag
     9061 atagaagaaa agataaatag caaaacaaaa gctatattag tagtgcattt atatggtcaa
     9121 gcaagtaata tgaaagatat acaagaatta tgtgataagt ataacttgta tttaattgaa
     9181 gattgtgctc aatctcatgg agctaaatat gatggaaaaa tgacaggaac atttggtgat
     9241 ataggttgtt ttagttttta tccaagtaaa aatttgggtg catttggaga tgcaggagct
     9301 atagtaacta gtaatgagga aatagctgat aaagtgaaaa ttcttagaaa ctatggctca
     9361 gaaaagcgat attataataa atttgtcgga tataattcaa gattggacga aattcaggca
     9421 ggtttattaa gagtaaaact taaatatcta aatgaaattg aaattgaaaa atcaaaaatc
     9481 gtagatagat atcttaatga aattaataat cccaaagtca tacttccaaa gatagaaaat
     9541 aattgtactc atgtatggca tttatttgtt ttacaagttg aaaaacgaga tacatttatg
     9601 gaatacttaa agaaaagtgg tatagagtct ataatacatt atccgatacc accacatcta
     9661 tctgaagcat atgcttattt gggatataaa aaggggagtt ttaatatagc tgagaactat
     9721 tcagataaag ttgttagtat acctttattt attggtatgg aagatgaaga agttagttat
     9781 ataattaaaa ttataaatga atattaaact actcataata atatcaaaaa taaatttttt
     9841 atatatcatt tatttaaatt tcgttaattg acatttttaa atattgatat attgtacaaa
     9901 taaaattgaa atatatggaa aaatatagaa ttaagatgag atttgtctta tatttttata
     9961 aattaaaaat attttcaaag agtttattat aaaattgtaa actatagtgt ttataatctt
    10021 tgtaattatt ggtaattaaa tttaaaaaat aaaatattta attatacaca aaaaagatat
    10081 ttaaaaaatt tgttatttat tgtatactta agttaaaact aaataggcaa atctagagaa
    10141 atctagtgac gcaaagctat agggactaag gtttatatac ataaactatg tcagccagtt
    10201 gccaaaaaga gtcctaggtg tattgtatac ctaagaaaag tctataatga ctgccttttt
    10261 ggcagtcatt ttgttatgga aaaatcactt tatttcagta gaaaatacac ataataacat
    10321 attttaccaa ttataacata aaataaagaa aaattatctc aaaaagttac tattttacaa
    10381 aaaagagcaa cttttcgaag aaatatttaa atacatatta aaattttttt atattttcat
    10441 gggacttcat taaaaaaata ttagttttct tactaaattg atacattatt gtattaatgt
    10501 aatggaaatg cgattaattt aaataaataa agaagtcatt ttttgtaata tagcaacttc
    10561 atttttttta ttaataaaca aaatagataa aatatatttt gaggaggggt gagtgtgaat
    10621 acatatgaca ttataaaaat gggattagat gcaactaatc taagaagtca gacaatagca
    10681 aataatatag caaatataaa tactgaagga tataaaagac attatataac ttttgaagaa
    10741 acactaaatg atgctatgcc taaaatagaa gaaaaaacag acaattctaa aggtttaaga
    10801 gtagatggta ataatgtaga catagaagaa gaaaaagtaa atcaagcaat ggcaacatta
    10861 caatataatg ctttgataag ttttgcaaat ggaaaaatag caatgaccaa atcaataata
    10921 agtgggaggt aattagaaga tgagtgtgtt cagtggaatg agaatatctg ctagtggatt
    10981 aacagcagaa agtttgaaaa tggatatcat atcatccaat gtagctaata taaatgctac
    11041 aagaggtcca aatggagaag catataggag aaaagttgtt tcatttgaag aaaactatga
    11101 taataaatta ggtatgctag gagtaaaagt tacatctgtt gaagatgata aatcacctct
    11161 taaagaagta tatgacccat ctcatccaga tgcaaagcca aatggatatg tagaatatcc
    11221 aaatgtaaat atattggtag aaatgacaga tttaataaca gcttcacgag catatgattc
    11281 taacgtagat acattgaatg ctcagaagtc tatgatatca aaagctttgg aaataggaaa
    11341 gtagggataa attatgccaa ttacacaaat taacaattta atgcaaggtg caaagttaga
    11401 taatttgatt ggagaagcaa agccattaac tcttaataat aaagaagaaa aaaagaattt
    11461 tgaagatgta ataatagata ctatagataa agttaatttt caacaagtaa cagcagatga
    11521 tatgaaagaa aaatttataa aaggcgaaga tgtttctatg catgaagtta tgttaatagg
    11581 tcaagaagca caactatcta tgcaatattt aatagaagtt agaaataaga ttcatgatgc
    11641 atatcaagaa atgaataagg tgcaaattta gccttttgaa caggagtaat aatcaatgat
    11701 aaccagtttt aaaaataaga ttaaggagca agttgctaaa tctaggacaa agataagttc
    11761 tttaaaaaag ggaactaaaa tagcattagg tataggggtt attgctatat gtttagcgct
    11821 agtatttaca gcaatatctg cgagcaaaaa taagtatgca gtcttatttt cagaactaga
    11881 tgctcaagat gctgcagata tatcagcaga gctagagtct aaaaagatag atactaaggt
    11941 aaaaggaagt acgatttatg tacctagaac agaagttgat aagttaaggc tggagttagc
    12001 gccaagtctt acaggtggtt ctaaaggatt tgcactaatg gatgatagtt catcaatagg
    12061 gcttactgat gaagaatttc agattaagaa acaaagaatg atacaaggtg aaatagaaaa
    12121 aacaataaag agttttccac aagtggaaga cactagagta catataacat ttggagagtc
    12181 atcagtattt gagaaggagg ctgttccagg gagtgcagca gtttatttga tgctaaaacc
    12241 agggacgact ttagaaaaaa accaaataaa gtctgttatg gcacttatat caggaagcgt
    12301 tacaaatata ccagagaaaa atgttcaggt tattgataac aaaatgaatt tattatctga
    12361 aggtattttg gaggatgaaa atgttgatga aaataatcaa ccaataaata gtggcattag
    12421 tgttgataaa aataaggcat ctgaacaagc attgaataaa caactagaaa agtctatttt
    12481 agaaatgcta gaaccgatat ttggtaaggg aaaggtgaaa gctacagtaa atgctgattt
    12541 aagttttgat acagctgaaa aaactgagat aaaaattgac cctgataaag ttgcaataaa
    12601 ggagacaagg tcgaaaaatt catctaaatc tgctgcaaat aatgttcaag gtgtagatgc
    12661 taacatgaat aaccaaggaa ataacaatgg tactaataca gaagatagtt tagatgagag
    12721 ttttgagtat gaaacaggta agattgaaac tcacactata gttgcgcctg gagaacttaa
    12781 tagattgaca gcttctgttg caatagatgg aaaaatagct aaaggtgttc aagctgatgt
    12841 agaggatatt gttaataatg ctataggtat ggatggagcg aggggagata ctcttagcgt
    12901 tgtttcaatg gtatttgacc cagaaggtaa gaaagaggct aaacaagagc tggaagagat
    12961 taaaaaagaa ggatttaaaa agaacataat aaaagcagtt attggagtag tagcagtaat
    13021 agcagttgga gctattggat acttaatata taagaaaaga agtgaacgag aagatatgga
    13081 ttatgaagat gaagattata tttctaaatc tgattctgtt gataggaagg ataatcctct
    13141 attaggagat gatccagaac tgacattaga ggaagctgtt aaaatgtatg cagaagaaaa
    13201 gccagaccaa gtaacagaga taataaagac ttggttaaat gagtaagggg gatagaaagt
    13261 gtccacggaa attacaaatg ttaatgcgtt tgacttaagt gatataaatg aaagtgataa
    13321 gaatgagaag gtagaaggtg agggtttaaa aaaagctgct gtattattaa tgacattagg
    13381 cccaaatgtg tctagtgata taataaaaag cttgcctgat aaacaagttc aaaaaatagg
    13441 tttggaaatt gcaaatattt cttcaatagc ttcaaaagaa agaagagaaa tcttaaaaga
    13501 gtttgtagaa ataaataggg caaaagatta tgttatagaa ggtgggcttg aatatgcaag
    13561 agagttatta agtaatgctt taggaaatgt taaagcaaac aaattacttg aaggtatatc
    13621 aataaataca agtacaaagc cttttaaaca tattataaaa ctagatgtaa agaagatatt
    13681 agaaatactt aggaatgaaa gtgcacaaac tatagccgtt ttacttgcac atatggaacc
    13741 agaaaatgga gcagaagttt tatcatactt agattttgat ttacaaaatg aagtagctat
    13801 gagaataagc tcaatgggtt caatatctcc agaagtaata aaggtaattg aaagttcatt
    13861 agaagataaa ttacattcaa taagtggtga tgattttaat gattatggag gggtgtctac
    13921 cttagttcaa atattgatta attctgatag aaaaacagaa aagaatattt tgggaactat
    13981 tgaagaacaa aacccggatt tagcagctca aattaaatct catatatttg tctttgaaga
    14041 tattgtcaag ttagatgata taagcataca aaaagtgtta aaagaagtga ctatgaaaga
    14101 tttagtatat gccttaaaag gtgtagatga tgagatttca gatgctatat atagaaatca
    14161 atcttctaga gcagcagatg cacttaaaga agaaatggaa atggttggtg ttataaaggt
    14221 tacacaagtt gaggcttctc aacaaaagat agctaatatc gtaagaaaac ttgaaagaga
    14281 aggtgccata actattgtaa ggaattttgg tggtgacttt gttgaataat aagattatta
    14341 aaagtaaaaa agcattatat aaaggagtgc tagatttaac cataatagat aaagttagag
    14401 tgggagaatc aaatgtaaat aaagaaaatg attgtagatt tagggatgag gtaataaaag
    14461 aagctataga atctgctgag ataaaaaaga atgagatatt agaagaagca aaaataaatg
    14521 cacaaaatat agaaaagcaa gcatatgaaa aagggtatag tcaaggtcaa aaaaatggat
    14581 atgaggatgg atataaagag tcatatgatg aatataccca aaaagctaaa gatgaagcag
    14641 attttataaa aaatcaggca aatttaatct tattacaagc taatgagaag atgactgagt
    14701 acataaaaga aaaaaataaa gagattgtaa gacttgctat taatatggcc agttctgttt
    14761 taaaaaagca tttcgaagat gaagaatcta tgagtgatct gttaaagcaa attattcaag
    14821 attatgaagg aagtagttca tttatagtaa gatgtaattc tttctataaa gataatatag
    14881 agaaagagtt tgaattattc aaagaggaaa catcactaaa atcaagtgta tttgttattg
    14941 cagatgatag tatagataaa ggcaatgcta ttatccaaaa ggaaaatgga agaataatag
    15001 ttggtattga ttgtgctatg gaaaaactaa aagaagaatt gcttggtgaa taaagtatgt
    15061 ataaaactga tatatctata gattttgaca aaataaataa gaaaatagaa aatttagaac
    15121 tcactatatc agaaggtaga gtaaagaaga taataggact tactgtagaa gttgaaggaa
    15181 taaaagcttt tgttggggag ttatgcgtta tatacaacca agttaataaa ccagtgaatt
    15241 gtgaagtagt aggttttaaa gataaagaag tcatattaat ggcgttggga gaattaacat
    15301 tgatagcacc tggttgtaaa gttatttcta aggggatacc tttaagtgtt atgtgtagtg
    15361 ataatttact aggtaaagta cttgatggtc ttggaaatcc tatagacaac tcagatgctg
    15421 ttttaggaga tagatacaac ctgaacaatg aacctcctga tccaatgaag agaaaaaaga
    15481 tacgaaatat aatggaaaca ggtgtaagag caatagatgc atttactact tgtggtgaag
    15541 gacagagaat cggcatattt gcaggaagtg gagtaggtaa gagtacgact ctaggtatga
    15601 ttgctaggaa tgcaaaagca gatgtaaatg taattgctct tattggagaa agaggaagag
    15661 aagtactaga ttttattgat aaagatttag gtgaagaggg aatgaaaaaa tctgttgttg
    15721 tgtgtgcaac atcagataaa gcccctctag ttaggttaaa aggtgctctt actgctactg
    15781 caatagcaga atattttaga gaccaaggca aaaaagtaat acttatgatg gattcagtaa
    15841 ctagatttgc tatggcacaa agagaagttg gtgtagcaat aggagagcca ccagctcaaa
    15901 aaggatatac accatctgta tttgcaatgt tgccaaaact tatggagaga acagggacat
    15961 cagataaagg ttctataact gcattttata cagtattagt tgatggagat gactttaatg
    16021 agccaatagc agatacaaca agagggatac ttgatggtca tatagtttta tctagagact
    16081 tggcaaataa gaatcactat ccttctatag atgtattaaa cagtttaagt aggcttatga
    16141 atgaaattgc ttcaaaagaa gacataaaaa tagcgtcttt tgcaagagac atgcttgctg
    16201 agtatagaga agcagaagat ttgataaata taggtgcata tgcttcaggt acaaataaaa
    16261 aaatagatga agcaatctat tatcatgagc atattattaa ttttttaaaa caagggataa
    16321 atgaaaagag ttcttttaat gaaactataa gtagtttgag aagagttttt gaataaacaa
    16381 ttaaaaaaat atttgaatag gttgtgatgg aattggataa aaactttaag tttagattac
    16441 agaaagtttt agacttaaaa gtgaaagatg aagaagagat aaaaatggaa tttgctaaga
    16501 ttcaacaaaa aaaaatagat atagagacta atttagaaaa cttagaaagt aattatagca
    16561 aatattctat aagtaaaaat aacgatagta ttcaaaatca aaaaataact attaactatt
    16621 tactagcttt aaacaattct ataatggatt tatcagaaga gttggataag tcaacaaatg
    16681 aacttgaaaa agctagaaag cagcttataa gcaaacagat agagagaaaa tcattagaaa
    16741 aattaaaaga aaaaaagtat ggacagtatt ataaagaaga aaatttaaaa gaacaaaaca
    16801 ctaatgatga gtttgcaagt atgagttatt taaggaatag acaagttcta taagaatagt
    16861 aggaagtgag gatattattg tatgaagata caagcagatt cttataatat tattaaagat
    16921 attggggata gaaaaagttc atctaagaac aaaaatataa aaaataataa atttgaagat
    16981 aatctatata aggcaacaga ccataaaaaa gttaaagata gaagggaagt aagtaagcaa
    17041 aatattagct cagataaacc ggaaaatagt gataatgagt gtcatttaga tgaagataaa
    17101 agtaatcact tagaagatga aaatacatat gaaaaagatt gtagtaagaa taatgaagct
    17161 ttgcagcaat tactgaatct tttaaaggat aattataaaa aagataaaga tataaacact
    17221 atattgaata atatagaaaa actaagtata tcagatgaat taaaacaaga acttaagctt
    17281 aataaaaata tattaaataa gattgcaaat caaaattcag agctaaataa agctaatata
    17341 aataactcta atgatataga aaatttagac atagttaaat taagagaact tttggaagat
    17401 aatgctaata aagatattga agtaattact aaaactacag aaaatgatac caaaaatata
    17461 gatttgtata gttttgatag caatagaatg gataatctta actcaaataa acagaaagat
    17521 gatagctctg atattttgga aaaactagca ggggtaaatg gaaataagag tgggaatttt
    17581 ggacaagtaa taaataaaaa tgttgatatg aataaaatta aaaatgataa tgtcaattta
    17641 aaacagatag aatcaaatgt aatggatgac tctataaaag ctattaagca tatgaaaaca
    17701 aatgatatac aagaattgac aattaaatta agaccaaaag aattaggaga tatgaatata
    17761 caattgttaa aagatggtga aagtatgaga gctgttgtga ctgttttcaa taaagatgtc
    17821 tttgactcta taaataaaaa catagcagat ttaaagcaac atcttgaact tactaatgta
    17881 aatataaaag atgtatcagt gcaaatgcac agcgataata caaatacatc tgataccttt
    17941 gataaagcat ttgaacaaca gaatagacaa aataaccaag aaaacatgag taagaagaat
    18001 acaaatgata agcataataa tgtagtcata gaagatgaca ttaaagaaaa tactattgat
    18061 gatgatagag tagatttact agcttagtaa gggggaagta ttgcatgtac ggaatagcaa
    18121 cggctttggc aggaactcag ggaaactata ggtcaaataa cttaagccaa cttgaaagaa
    18181 atattaatga tattgccaat aaacaagtta gaagcaaagg aaatcagaca gtaacagaca
    18241 atgggactcc aattatagga caaggtgatg atgctgataa agacttgttt atgaagatac
    18301 ttgtggcaca gatgggtaat caagacccaa tgaatccgca agacccaaca gaatatgtgt
    18361 cacaattagc acagtttgca actttagaaa agatgtcagc tatgaatgag aagctagatg
    18421 tacttttagc cttaagtaat tccactctaa taaactctgc tttaagtatg gcaacatcat
    18481 taattggtaa agaagtagaa gtatctgggg aagagaaaga agatgaaaac attgtaggag
    18541 tagtaaagtc cacatatata aaagatgggg aagtacactt agaattagaa gtagatggaa
    18601 gtgacaaaac tgtaggtgtt aaatatgaaa aattacttaa aataggagag gtagatgaaa
    18661 attcaggaga agaaaatgat tcttcagaac acgaatctcc agaagaagca taatattaaa
    18721 tgagaaaaga ggtaaattca tgataaaagc aatgtattca ggtgtaagtg gaatgaaagc
    18781 aaatcaaaca aaattagatg taataggtaa caatgtagcc aacgctggaa ctacttcttt
    18841 taagaaaagt tcagctagaa taacagattc attttatcaa actgtactat atgcaagtgc
    18901 tccaacagct gcattaggag gaacaaactt aggacaagta ggtgtaggta gtaagatatc
    18961 aagtataaat aaagatatgg tacaaggaaa tgtacaacca actaatagac catctgattt
    19021 aatgatagat ggagatggat atcttccagt agtaagacaa ggaacagtta tgtatacgag
    19081 agatggttct tttaatttag atacaggatt taaagcagct gatggtgctt tgaagaatat
    19141 taaaggtgga agacttgtaa atggtgatgg atatatgtta caaggtatga tttatgatgg
    19201 ggaatataaa gctgatactg gagaatttgt taaaaagggt gatgctaaag gaaaagagcc
    19261 tattgtaata ccacttcaaa gtataagtcc taaggatgga acagttcaaa atgtactaga
    19321 gtataatata tcaaaggatg gaacagtaga atttttattg agtgatggtc aaagaactca
    19381 atttgtctat gatatacctg atggtgctaa ggtaggagat acacctgctg gaatagataa
    19441 attaaaaggt acaatacaaa aagtgcaaac atatgcattc caaaatccag caggactaga
    19501 tgcagaagga ggaaacttgt ttaaaccatc agcaaactca ggagacccac aaatagcagg
    19561 agctacaggc acaataatac aaggggcaat agaagcttcc aatgtagata tagcagaaga
    19621 atttacagaa atgataatag caagtaggtc tttccaagca aacagtaaaa taatatcgac
    19681 atcagacgag atacttcaag aaataataaa tcttaagaga tagtaggtac atattatgat
    19741 aagagtaacg gatttaaacg gaagaaaata catattaaat tcagacctta tagtgaggat
    19801 tgattctgta ccagaaagta ggattctcct tacaacagga gaaaaaaacc ttgtaaaaga
    19861 gtcggtagat gagatagtag ataaagtaat aaagtataaa agaaaaataa atgtaggtta
    19921 tattaggagc gaaaaataat gaaaaaaaca gattcactga catttattgg actaatagta
    19981 tctacagtat tagttttagt tggtgccgca aaaggaagta gttcagggtt aaagaatttt
    20041 tttgatgttt catcaatatt aatcacagtg cttggttcat ttggagctct aatgattaca
    20101 tttactatag atgatataaa acttataaaa aatgcattac aatactcatt taagacaatg
    20161 agtgtatcaa agttagattt actagaacaa tttaaaacac tttctaaaaa agctagaaaa
    20221 gaaggtcttt tatcaataga gagtgatgta atgggaatag aagatccatt tatgaagaaa
    20281 gggttagagc tgtgtattga tggattggaa atcaatgaga taaggtccat cttagaacta
    20341 gagatagatt ctgttgaaga tacaaataac agatactcta aactatttaa aacttgggga
    20401 acctttgcac ctgcttttgg gatgttggga acactaatag gtttaataca aatgttagct
    20461 gaccttacat ctccagattt aatagcatct ggcatgggaa aggcattaat tacaacgttt
    20521 tatggttctt tacttgccaa tatcgctttg aacccaattg catataatat agatgagaag
    20581 actgaaaaag aaatttatgt aaaggaaatg atgttggaag gtataataag catacaatct
    20641 ggggagagca gtatagtagt tgaggaacgt ttagccacat acctttcaaa caatgagaag
    20701 ttagaaatta tgaaatccaa taaaaataca gaaagagcaa tgagcaatgg cgcgtaaaaa
    20761 aaataagaaa aaggatgaga taaatccaga tgcatggctg gctacttatg cagatactat
    20821 aacactgatt cttacatttt tcgtattatt gtatgcaaca tcagttgtag atatggaaaa
    20881 atttaaaaac atagcagatg cgttaaaagg tcagttttct gggacaagta tatttagtac
    20941 gggttcaagt acaagtgaga aatctccaat agacagtgtt ttagtggata aaaatgataa
    21001 atcaaattta gaacaggatt taaaagataa agttaataat tctaacttac aaaatagtgt
    21061 aacagtcaaa gatgatagta gagggatttt actagagtta gatgattcaa ttttatttga
    21121 ctctgggatt tctgagttaa aagtagatag taaagctact cttaataaag tatatgacat
    21181 gataaagatg atgaaaaata agatagttat agaaggccat actgataatg tacctgtaaa
    21241 atcaagtaca catgaatcca attgggattt atcttctagt agagcagtaa gtgttgtaag
    21301 atactttgta gaagaaaagg gcatggaccc tagactattt tcggcaacag gatgtggaga
    21361 gtatcaacct ttggtttcaa atgaaacagc aaagggaagg gctgagaata gaagagttaa
    21421 tatacttata actattgact aggaggaaga ggtttgttca aaaataaaaa aattattata
    21481 attattttga tactgattat tttctcagcg ggagcaggtt tttttatatt aggagaaggt
    21541 ggaaataaac aagttgacaa gattgcagat ttgtttattc caacaggaaa aggtaaagat
    21601 gaagtaaaga ccgaaaatct tgacttagaa gagatggtat taaagctagc tgatgaaggt
    21661 gtaagatatt taaaagtatc aataactgta tcttatgatt cttcatataa agatatagaa
    21721 aaaaatacgc ctttaattag ggataatatt ataaattgtt ttatggcaaa aagggcagat
    21781 gattttactg ctgataattt aaagaacata aaagaagaaa taaaaaatac attaaatata
    21841 caactaggtg aaaatgtaat tcaaaatata tatttcacaa atatagtagt gcaataaaag
    21901 gatggtaaga catgatactt tatttactaa aaatattaat atgtatccca ataattttaa
    21961 tattgatagt cttatcttta aaaattagcc aaggaacttt attaaaaaaa tataatgata
    22021 aatatgtaaa aatactagat attgtaaata taagtaaaaa caatagcata ataattttaa
    22081 aaataggtga agaaggatgc attatggcat cttcttcttc tagcatgagt aaaataaaag
    22141 atttgaccaa agaagaaata ttaaaaatag aaaacgacat taaagaaaga aattttaaaa
    22201 ttcaagattt taaaatggaa agaattaaaa agaaatatga tttcagtaga tatattggaa
    22261 aatttacaaa aaaggaagat aagtaaatgg aactattatc aaaattacct ttggctgatg
    22321 taccatatac aagttcaatg caattgtttt tatttctaac tgcattaatg tttttaccat
    22381 ttgtaatgtt catgatgaca agctttgtca gaatagttat aagtttatca tttttgaaat
    22441 cagcattagg agcacagcaa gcaattccaa gtcaaatttt ggtaggactt gcaatagtat
    22501 tgacaatatt tataatgaga ccagtattaa atgagataaa cgaaaaggca ttacaaccat
    22561 atatgaaaga agaagttact atggaagaag ctatgaagga agcagaagga cctattaaag
    22621 agtttttatt aacacaaacc agacagacag atttagattt atttgtagaa caggctggtt
    22681 taaaagaaaa gaaattaact cgtgaaaata taccactatc tgttgtagtt ccagcatttg
    22741 ctataagcga actaaaaact gcttttcaaa taggtttttt aatatatata ccatttttga
    22801 taatagacct tgttgtggca agtgttttga tgtctatggg tatgtttatg ttgcctccag
    22861 tcatgatatc attaccattt aagttattat tatttgtaat ggtggatgga tggaacttga
    22921 tagtaaaaac attgatattg ggatttggat aggagaaaaa tagtatgagt gaatttatga
    22981 taatgagtgt tcttaaaaat ggcatgttta caggagctat gattgcagct ccagtactca
    23041 ttgtttctct tgtagttggg cttttaataa gtgtgtttca agctacaact caaatccagg
    23101 agcaaacttt gacttttgta ccaaaactaa tagctattct tttagtagta gctattggtg
    23161 gaagctggat gttacatact cttattagtt ttacttctga gatattcaat atgatatctc
    23221 ttataactaa ataagtagga tacatatgat ttttgtattt attagaatag tagcattctt
    23281 tggaacacta agaatactat ttccagctgg tacacctgct ttatttaagt cactctttgc
    23341 aatcattata tcaatattga tttcaagtac tatgcaaatt gaatatgcaa caaatataga
    23401 caacattgta ttgtttacct tatatggtgt aaatgagacc ataactggga ttatgcttgg
    23461 atatataacc aacctatgtt tttatagtat cagaatggcg ggttctatga tggaccaaca
    23521 gatgggatta tcaatgatta atatgtttga cccaaattca atgactcaga caactttaat
    23581 tgataatctt atgaactgga cagcacttat gatatttttt agcatggatg gtcatcatgt
    23641 tttaattaga ggtataaggt atagttttga gttaattcca ataggaaaac catttgtaga
    23701 taataacata gattatataa taaacatatt tgtgcagtgc tttttaactg gattcaaaat
    23761 agcaatacct attgtacttt gtctgcttat ggcagatttt attttagggc ttatatcaag
    23821 aagtgtacct caattaaatg taatgatagt tggtatgcca ttaaaaatat tggttggtat
    23881 tgcattattt atcatatcaa tacctttaat tgtcaatcaa ataagtcatt tattaagtca
    23941 aataccaaag atgtatgagg gaacttttgc actagctcct atgtttttta tgggttcagc
    24001 agataaaaca gaagaagcta ctccaaagaa aaagggagaa caaagaaaga aaggtaatat
    24061 agcaaagagt agagaattac ccgttgcaat gactctactt gcattcacct tattagtacc
    24121 tacattattt tcatatgtag tagatacact taaatcttcg cttaattatt ttttgagtct
    24181 agatttttat atgaacataa attattcaaa cctagagaaa ttagttatag caggattaat
    24241 ggattttttt aagatatttt taccaatagc tattcccttt ttagttttag gcataatagc
    24301 aaacctattt caggtgggaa tactgtttac tggtgaaact ttaaaaccaa atttatcaaa
    24361 attaaatcca attagtggat tcaaaaacat gttttctatg agaagtttgt caaccttaat
    24421 aaaggataca gcgattatat ctattttggc ttacatagga tatacattct tccaagataa
    24481 ttatttagat atattaaagc taggtaacat atacctacca actttaatgt acacagttaa
    24541 agacttagta tattcaatat tgagtaagat ttgtgtagct atgatagcta tagcagttgc
    24601 agattatgtt tatcaaagat acagtcataa aaagcaactg agaatgacaa aacaagaagt
    24661 taaagatgaa tataaaaact cagaaggaga cccagaagta aaagctaaga taaaacaaaa
    24721 acaaagacaa atttcgtctc aaaggacaat gcaagcagta ccaagtgcta ctgtaatagt
    24781 aaccaatcca acccacttat ctatagcagt gagatatgaa aaagggaaag accaagctcc
    24841 agtagtggtg gcaaaaggtg cagattatct agcttttaaa ataagggaaa ttgcaaaggg
    24901 aaataacatc cctataatag aaaacaaacc tattgctagg ttgttatata agcaagtaga
    24961 aatagaccaa gaaattccag aggacatgta tcaagctttt gcagagatat tagtggcagt
    25021 atataaaatc aaaaatagat acaaagtccc caaaaggtag gataagtaat gaataagttt
    25081 aatttaaagg aaaatatgga tgtaatagtg gcatttggtg ttgtagggat tgttcttatg
    25141 atgatagtgc cattacctac atttatatta gatattttac tggcaattaa cataagttta
    25201 tctgtgctaa ttttactaat gacattattt acaacaaatg tacttgattt atctatattt
    25261 ccaacagtgt tacttgtgac aacactattt agattgggat taaatctttc atcaactaga
    25321 ttgattttaa cacagggata tgcaggtgaa gttatagagg catttggaag ttttgttgta
    25381 ggtggaaatt acgtagtagg aataattata ttcttaatta tattaattgt tcaatttgtt
    25441 gttataacca atggttctgg aagagtatct gaagtaacag ctagatttac gttagatgcc
    25501 atgccaggta agcagatgag tatagatgca gatttaaatg caggagttat agatgacaaa
    25561 actgctagaa aaagaagaaa agagcttcaa caagaagcag atttttatgg ttctatggat
    25621 ggagcaaata agtttgtaaa gggagatgcc atagcaggtc ttatagtaac agcaataaac
    25681 ataataggtg gaattgtaat aggagctgta atgctgaata tgactcttat gggtgcagca
    25741 cagacatatg taagacttac tataggggat ggtcttgtaa gtcagatacc tgctctatta
    25801 atatctacat cagcaggtat aatcgtaaca agagcttcta ctgatgaaaa ctttggtgac
    25861 ttagtaggta aacagttaac ggcaatacca aaagcagtaa tgatgactgg ttgtgttcta
    25921 atcgtacttg gtatgatgcc tggattacct aaaccagcat ttttttcact aggtatagga
    25981 gctatagcag caggttactt tttaggaaga gaaaagaaag atactttaga agacttggag
    26041 tttgaaaaac ctgatatggt aaacccagat aaaaatgaag tagaagatgt aacaaattta
    26101 ataaatgtag aatcaataga agtagaaatt ggatatggtt taatatcctt agctgatgaa
    26161 tcagcaggag gagatttact tcagagaata gcatcaataa gaagacaatg tgcaatagat
    26221 atgggtatag tcgtacaacc cataagaata agagataact tacagttaaa tccaaaccaa
    26281 tacaatataa aaataaaagg aaatgtagtt ggtgggtatg agataatgcc taatatggtt
    26341 ttatgtatgg accctatgaa tcaaggattt agtatatttg gaataaagac aattgaacct
    26401 acttttggaa tagaggcact ttggatagaa agtgacaagg tagaagatgc agagttaaag
    26461 ggttatacag ttgtagattc atccacaata cttataactc acttactaga tataataaaa
    26521 tcaaatgcac acgaattact gggaagacaa gaagttaaga ctattataga tgcagcaaga
    26581 gaaaattata gtgctgtagt agatgaattg ataccagatt tgatgacact tggtgaaatt
    26641 caaaaagtac ttaaaaatct gttaagagaa aaagtaaata taaaggatag agttacaata
    26701 cttgaaacgc ttgcagacca gtctagaaat acaaaagata tagagcttct tactgaatat
    26761 gtaagaatag ccttggctag aagtatttgt aataatttag ttgatgatga taagacaatt
    26821 gtagtggcta cattgtctcc agaaactgaa gagttggtat ctaataattt acagaggtct
    26881 gtaaatggaa cttatccagc agttgaccca gaaaatacaa ataaaatatt tgaaagtata
    26941 caagaagtaa tgagcaatgt atatttcaat cataatatac cagtaatagt agtatcacca
    27001 aagataagag ctccatttag aaaattagtt gaaattgtat atcctaattt gactgtatta
    27061 tcattaaatg aaatacctaa cgatattaaa atcaaagcag aaggtgtggt gagcatatat
    27121 gatgacgaaa aagtatacag ctaacacaat tcaggatgct atgaatctag ccaaaatgga
    27181 attgggtgac aatattacat taatagataa aaaagaggta agaaagtctg gaatacaagg
    27241 tatcttttca aaaaaagata ttgaactaac tattggatgg gaaaagagag aaaatgtaga
    27301 acaaaaagat ttaaaacgag agatagaaca attaaagtca attattaaca atatggggtt
    27361 tgataataag aatgataatg atatagataa aatatgtaaa aatctactaa gtttagaatt
    27421 gaatgaagaa attgtagaat ctataagaat tgatttgcaa gaaatgaagt tcaatggaat
    27481 cgatacaagt aaaaatttag tagaaatttt aaagaaaaag attaaaatag aaaatcaagt
    27541 aataaatggt aaaattgctc tagtcggacc accaggagta ggtaaaacga ctacaatagc
    27601 aaagttagcc gcaaaattag tttttgaaga aaataaaaaa gtaggagtaa taactataga
    27661 tacatacagg attggtgctg tagaacagtt gaagatatat actgatataa tgaatattcc
    27721 ctttaaaggg gtaataagtc ctgatgaaat ggaattggca cttgacgaga tgaaagattg
    27781 tgatgttgta ttaatagata caacaggtag aggctacaaa aactctatgc aaatactaga
    27841 aatcaaaaat cttatagata aagctgaaac tgataatata catttagttt tgaattgtac
    27901 aacaagagaa agtgatacaa aagcaattat agattcatat agaaatgtga attttaaaag
    27961 cttaataatt acaaagctag atgaaacaat aacatatggc tcaatattta acataatgaa
    28021 ttatgcgcaa aaaccaatat catatattac aacaggacaa aatgttcctg atgatattat
    28081 aaaacctaat gaagataaga ttataaggtt actattagga gttgaaagta tatgatagac
    28141 caagctcaaa ttttgagaaa aatagcaatg gaaaaaagag gacttgatga gtttatagta
    28201 gagaatgaga atgtacctaa gataattaca atagcttctg gtaaaggcgg tgttggaaag
    28261 agcaatctcg ctacaaattt gtctatatgc ttgaccaaac ttaataaaaa agttcttata
    28321 ttagatgcag acataggaat gtctaatata gatataataa tgggggtaaa tgtaaaaggg
    28381 actataattg atgtaattaa tggcgaaaaa aatatagaag atataatttc acagactaag
    28441 tatggtgtaa atataatatc tggaggttct gcccttaatc atatagaaga ctttacagaa
    28501 gctcaaagaa ataagtttat acatagcata gaacaaattc acgatgtgga ttttataata
    28561 attgatacag gagctggtat gagcaaaagc ctattgtcat ttatatactg tagtactgaa
    28621 tttttcttaa taacaactcc agaaccgaca tcattgactg acgcatatag tttattaaaa
    28681 gctataagta attttggcat aaagagaagt gcaaatataa taatcaatag ggtaattgat
    28741 ttagaagaag caaaatctac atacaaaaga ataaaaatgg ttgtggacaa atttctaaac
    28801 cttaatctag aattgtatgg atatataata gatgacaaaa aagtaagttt atgtgtaaaa
    28861 aaacagatac cattcatttt agaatatcct acaagtattg catcaaaatg tattatagcc
    28921 atagcaaaga gaatggtaag tcagtcaaga gaagatattg ttgataataa aagttttcta
    28981 agaaagatgt ttagtatatt taaaagctaa ggaggcgtag ttaatgaata gagaagaatt
    29041 aataaaagag aatatgcctc ttgtaaagag tatagcaaga aaatttttta taccagggaa
    29101 aggttttgaa tatcaagact tagtaaatag tggagtcatt ggattgattg atgcaataaa
    29161 taaatttgat gctgaaaaag gggcaaagtt ttctagttac tcttatataa aaataaaatc
    29221 tgctatatta gatgaaatta gaaatcaaag tccaatttct aaacataatc taactaaagt
    29281 aaataagtat aatagagtgg tagaaaagtt gcaatctaaa ttattaagag agccaacttc
    29341 atatgaaatt gcaaaagaat taaaggtttc agaaaaagaa cttcatgata tcgaaagtaa
    29401 tatagatatg ttaaatattg tatcattaaa ctatgtaatc tttgaagata caaatgaaac
    29461 tgtacaagat gtaataagtg atagagaaga ggaagctcca gaaaatataa tagaagaaga
    29521 agaaaagtta gagattctat ccaaagcaat tagtaattta aatgaaagag aaaaattaat
    29581 actttcactg tactattatg aagatttaaa tctaaaggag atagggaaag tgctaggtgt
    29641 ttcagaatca agagtttcac aactccacag aaaatcaata agaaacttaa gaaacaagat
    29701 aaaagaactt aaatattcta tatagatggt gattgataag atgatacaaa ttatattaat
    29761 agtagtgtct attttaataa tagtaactat agttataaat ttacataagg aatcaaaaaa
    29821 taaagataac agatactttg ataaaatatt tgagcaagaa tatgaagcaa atgatagatt
    29881 aataattgca gaaaaaagaa gattcttttt agacaaagta cttgcagaaa aaagaattaa
    29941 tagtcatata aaagtttatg aaaattataa cctaataaag gctaatgaag aaagaaagga
    30001 aaacatattt atagaatcaa aaaaggaagt aagacaagaa aatgagttat ctcttaaagt
    30061 gaaacatctt ataagttcag gttatgatga tgtggaaata tgtaagatgc tagatattgg
    30121 aaagggggaa ctgttattaa taaggagttg ttacaaaata taaggatatt attatgtgat
    30181 aaaaaagtat tcttaggaat aggtattggt atattaatat caactttatg tataatgctt
    30241 tttagtaata atgatatgag taaggcagag atagaaaaaa aggccagagc gttaggcatg
    30301 aaatatacaa gtgagatgaa agttttagaa tagatgatat tgtttagaca tttacaaaaa
    30361 aggaggtcat aatgtgataa gaggattata tacagcagtt tctgctatga taactaatca
    30421 acaaaagcaa aatgttgttg tcaataacct agctaatatg gatacaaatg gatataaaag
    30481 taaacaactt ttgactaaaa gttttgatga attaaagttg gagggttaca ataactacgc
    30541 aaatggaact aaacaaaagc agattatagg cgatataagt ccaggtattt ctatggatga
    30601 aactatcaca aattttaatc aaggacctat aaaaactact gataataaaa tggatgtagc
    30661 tattcaaggt aagggatttt ttctagttag tgatgcagct ggaaatcaat tttacactag
    30721 aaatgggaac ttcagaacag acaatcaagg tgaccttata acaagtgaag ggtattatgt
    30781 acttgggacg aatactgcta ctggtgctgt aggtcatata aatgtaggaa atcaaaaatt
    30841 tgaagtggca aaagataata caatatcact agacggaaat gctatgtata aatttaatat
    30901 tgtagatttt aataactaca ataacttaaa aaaagaagga gataacttat attctggagg
    30961 aggagctatg aaagtaaata atgcacttac aatacaaagt gcgatagagt cctctaatgt
    31021 agatatggta tctgaaatta ataatatgat gacaatatca agagaatatg aggcaaatca
    31081 aaagataatt caggctatgg attctaaatt agcaaaaata gcaagtgaga ttggttcagt
    31141 aagataggta ataggaggtg aatttttatg tacacaatgt tttatactag taaaacagct
    31201 ttatcagcaa atcaaagtaa actagatata atatctaaca atatagcaaa ttctgattca
    31261 acaggatata aaaaaataaa tatggaatat tctgatttag tggatgaagt actaaataga
    31321 ccatcatatc ctacaaatgg caatgatata tcgactggaa caggagctaa ggcaacagct
    31381 cccatgagaa attatgaaca aggtgcattg gctcctacag atagtaagag taatttggca
    31441 atagatggag aaggattctt tagagtgata agaaaagatg gtacatatgc atatacaaga
    31501 aatggtggat ttaatgtaga tgctttaggt aagattgtag atgataatgg aaatatatta
    31561 gatgtccaat ttgatgcagg atataactat aataatacaa atatagatag tacaaacctg
    31621 acagtttcaa gaaatggaga gctattcgta gataataaaa aaataggaaa aatcaactta
    31681 tatcaaccta taggaactca aaattttata tctgaaggag atagtttatt cgtcgcaact
    31741 gatgcagcac agattaaaca agttgagaaa gtcgatatag ttcaaggcta tagagagagg
    31801 tcaaatgttt ctttacaaga agaatttgtt gacttaatag ccactcaaag agcatttcaa
    31861 atgaactcaa agggaataaa gacagcagat gaaatgtggc aaatagcgaa taatttaaga
    31921 gctaaataat tatgtaaggt gaggaatatt catgaatgat atgaaagagt acgattttgg
    31981 caaacctcag agttattcaa gagaaaattt aacttgttta aattttttat tagctgaatt
    32041 ttgtaaaaaa tataaaaact atataattta tgaacttaag tgtaattcta gtatggttgt
    32101 tgatagtata gaccaagtaa attatcagac ttttttagat agagtaactt cttcatgcgt
    32161 agtagtacaa aatgcaatgg aacctgttat gaaaaacttt tcttttagaa tagatagaag
    32221 tgtagctgat atgtggattg atataacttc tggaggaact ggagttgtaa aggataatga
    32281 tagagaactt acagaacttg ataaaaaagt gcttttacac cttatggatg atttagtaag
    32341 aaatatgcac ttatttgagg gttttgaaaa tatacaagta ttggatacac atacacatat
    32401 taatttgcca caattatgtt ctccaactgc accagtatgc gttgtagatt taaaagtgct
    32461 aaatgataat gagtatattg gaagtgtttc tctttgcttt ccatacaatg gtttagaggc
    32521 tctgttagaa agtatatctg ttatagaatt ttttgataat gatgtaggag atgattcaga
    32581 ggaatttacc caaaaaatct ataatagtgt atctaatata gaattatcag ttattgcaga
    32641 gataggaaaa gtatcaatta atgttgagga tttactcaaa ctagaagttg gagatgtaat
    32701 agtaacaaat aaaaaaataa atgattatat agatatattt gtagaaaatt caaaatcata
    32761 cacagcaaca ccaggattta tatcaagtaa aaaaggtgta aaaataaatg atgctgttgg
    32821 aaaagaggtg tagttatgga caatagtaat cttatttcag atgaagaagc aaagatgtta
    32881 ttaaatgata aagttgaaag tgaagttgat ggagatgatg agttagcctt agatgtctct
    32941 gaagttaatc gaaataatat acaaaggata cttgacctta agttagaatt atctgtagtt
    33001 ataggaagaa ctaagatgac tctaagagat attttaaatt tacataaagg ttctcttatt
    33061 gaactggata ctttggcaga ccaagatgtg gaaatactaa tagataataa ggttttggct
    33121 tatggaaaag tagtggtggt agatttaaat tttggtgtaa agataacaag tatagtaagt
    33181 gaagaagaca tggtaaaatc tcttgtttag agataacatc aattaatact taaggcatga
    33241 ggtggtactt attttaaact taaatgatat aaaaaaagat atactaaaac tcaataaaaa
    33301 agactcatgt tctctatata atgaatctat taataatata aataataatt gtatatcaac
    33361 tggattaaaa tttttaaaac aagcaagaga tttaaaccca gatgatgttg atatattaaa
    33421 tctcacaggt cttgtaaact tactaaaatg taattttgat gatgctgtag aaagtttcta
    33481 taagagttca ctttgtgaaa aaactgctct gtgtgaaaag tatataaaca tgcttacatc
    33541 tgaggagttt ttaattttct ttgaaaagta caatcaactt ataaggttaa taaataaagg
    33601 aatgtataaa gaagctatac aagggtttaa acttataact gaccaatact gtgatttaat
    33661 agaaccttat gagttgcttg ccttactgta tgacaaggaa gaagaatata taaaatttga
    33721 tgaatgttta gaagtattga agattattga taaggaaaat tatttattaa atcaagaaaa
    33781 taacacatta tatatgtata atagtgctaa tatacaaact aaaagtaata taaaagtaga
    33841 tgattataag aatgagttct tacataaaag tagtagtaac cataaaatta atgattataa
    33901 tgatgtaact aaagaaaaga gttcaagcaa aaaccagaaa agttcagatt ctaataagaa
    33961 aaaaagtatt aaaaaaaata agtacctata tatagccata atattaggaa tattattagt
    34021 aggacaaagt atatatagtt cttataagat gaataattta actgataaaa tatctaaaaa
    34081 taatgaaact aaaaatgaag agtcaataga ttctaacttg actaagaaag aaaataatat
    34141 agaagaaaat gaagatatga gtaaggcttc taatataaat aagagtaata aaaacattaa
    34201 taaagaggat gatgtaaaat ctaaaaaaaa tactgtagaa aatgaagatg ataaagattc
    34261 tgacttattt acagaggatg aattgatgtc taaggcgaat actttaaaat cagaaaagaa
    34321 aactaaatct tctatacaac tatataagaa agttgcagat ataggtgaaa ataaagggaa
    34381 tacatctgaa gcaacttatc aagttgctat tctcagtgaa aagttaaaag actataaaac
    34441 tgctgaagaa tattataaaa tgtatgtaga aaattactca gaaaaagatg cttattttga
    34501 tgaatcttat tataatttag gtatgatgta ctataacaat ggtgatttaa aaaattctaa
    34561 attgacatta aagaagttgg ttaataaggt accaaatagt atgtataata attcaaaagt
    34621 aaaagaaatt ttaaaagaag aatagttaaa ttagataaga aaaataaatt attttatttt
    34681 aaaataatat gattataata tattgacata ccattttaaa aaatttaaaa tattaattat
    34741 aaaatgagga gggataaaaa atggaatttg aaaaagggag tatttcaatt catacagaaa
    34801 atatttttcc tataattaaa aaatggttat actctgataa agacatattt ataagagagc
    34861 ttataagtaa tggatgtgat gcagtaagta aacataaaag acttgtatca ctaggagaaa
    34921 tatcagaaaa taagtcatca gattataaaa ttacagtatc tgtaaataaa ggagaaggta
    34981 cacttaaatt tattgacaat ggaattggta tgactgaaga agagataaaa aaatacataa
    35041 atcaagttgc tttttcaggt gctgaagatt tctttaataa atataaggat aaaatggaag
    35101 agtcaaatga tataataggt cattttggat taggatttta ttctgcattt atggtgtcta
    35161 aaaaggtaca aatagataca ctttcatata cagaaggagc gactcctgta agatggatat
    35221 ctgaaggtgg tacagaatac gaaatatctg aatcagatgc tagaaatgat agaggaacta
    35281 ctataacact atttattgat gatgatagta aagaattttt agatgaattt actgtaagag
    35341 gaataataaa taaatactgt tctttcttac cagtagaaat atatttagaa gatgttgaaa
    35401 gattagaaag agaagctaaa gaagcagaag aaaaagctaa aaaacaaaag gaagatggaa
    35461 aagaagagat tgtagatgca aaagtaattg agcctttaaa cgacactaat cctctatggt
    35521 taaaatctcc aaaagactgt actgatgagg agtataaaga gttttataga aaggtattca
    35581 atgtatttga tgaaccttta ttttggatac atttaaatgt agattatcct ttcaatttaa
    35641 agggtatact ttacttccct aaattaaaaa atgagtttga actgactgaa ggaaaagtaa
    35701 aattatacaa caatcaagtg tttgtggctg acaatataaa agaagttata ccagaatttt
    35761 tacttttatt aaaaggagtt atagactgcc cagacttacc attaaatgta tcaagaagtt
    35821 tcttacaaaa tgacagggat gtaagcaaaa tttctaaaca tataattaaa aaagtagctg
    35881 ataagttgaa atctctttgt aaaaatgaaa gagaagaata caataagttt tgggatgata
    35941 tacaaatatt tattaaatat ggttgcttaa aagatgaaag tttctatgag aaggtaaaag
    36001 aatgtatatt attcaaaact attgatgatg agtatataac attacaagat tatttagaaa
    36061 aatgtaagga caaacatgaa aataaggtat tttatgtaag tgataaggaa cagcaatctc
    36121 aatacattaa actatttaaa gaatacgact taagtgctgt tgttttaaac tcatcaatag
    36181 atactcattt tatttcattt atggaatata aagagaatgg agttaagttt aatagaatag
    36241 atgcagacct ttctgatgta ttaaaagata aaaatgaaaa taaagatagt gaagaaaaca
    36301 aagaagagat agctaagata gaaggtctgt ttaaagaagc tgtcggagaa agagtgaaga
    36361 attattctgt agaaggattg aaaaatgaag acactccagc tatggtatta gtatcagaac
    36421 aatctattag aatggcagaa atgcagtcaa gatttgctgg aatggattta ggaatgaatt
    36481 ttgaggaaga aaaaactctt gtaataaatg agaacagtcc aataatcaaa aaattggttt
    36541 ctcttaaaga tgatgaggaa aagaaagata agattacgct tatttgtaac cagatagcag
    36601 atttagcttt actttctaat aaagaattaa agccagatga gttagattca tttgtacaaa
    36661 gaagtaataa gcttatgagt cttttgatag aattataaga ttgaatttga atacattgaa
    36721 gcaaatttat aaaaagtatt caatatcagt gataagaaag aagtgtctca aaatgaactt
    36781 ttcagttcat gaggcgcttt ttttatgtga aattaaattt attttaatca tttcaacaat
    36841 gaaaaatata tttatctcta ttttgagaca gaccattctt tattttttta tctttggtta
    36901 attttaaata tttaagtagg ttctaataaa aaactctatt tagttaaata tagttaactt
    36961 gatatataat aagataatac atataattaa gtaaaagatt gttttttagt ttatgtttaa
    37021 atacataatt acactttgtt aaaaacataa aattattact aaagtagaaa taggaggttt
    37081 tagaatgaat tttaattata atttgccagt aaatatctta tttgggagag gcagaattaa
    37141 tgatgtggga aaagaagtat ctaaatatgg caaaaaagta ttgatagtaa caggtaaaaa
    37201 tagtacaaag aaaactggat tacttgataa aacaatagat ttactaaaag actctaaaat
    37261 agaatatgaa gtttttgata gagtagaaca aaatcctctt ataactacta tatattcagg
    37321 agtagaaatt ataaaatcaa ctggatgtga ttgtgtttta ggtcttggtg gtggaagcat
    37381 tatggatgct gccaagagta tagctttttc ttataaaaac ccaggagatt taaatgatta
    37441 tatatttgga attagacaag gtgaagaagc tttacctata atcttagttc caacaacatc
    37501 aggtacaggt agtgaaggaa attgttttgc agtacttaca aattcagaaa ctaaagataa
    37561 aaaatctata aagaagaata gtatgtatgc aaaagcatca ataattgacc cagaacttat
    37621 ggttacaatg ccaaaacata taattgcatc agttggattt gatgcacttg cccataatat
    37681 ggaagcatat ctttctaatg gaagaaaccc tcttgcagat gtacaagcta tttatgggat
    37741 tgaacttata tcagaaaacc taataaaggt atataatgat gttaatgatt tagaagcatg
    37801 ggaaaaaata acacttgcaa gtactattgg aggaatgacg attggtacag cgggtacagc
    37861 cttgccacat ggaatggagc atcctgtaag tggtcttaga gatgtaatgc atggaaaagg
    37921 acttgcagct ttgactccta ctattataga aagttcatgg gatagtgata ttgaaagatt
    37981 tggtaatatt tcaaaggtat taggaggaac ttgtgcagaa gattgttcag atgcaattag
    38041 aaatttcctt aaaaaaatag atttagatat aaaactaagt gatttaggta ttgaaaaatc
    38101 agatatagat tggttaactg ataattgtat gaaaatatca gttgcaaata ttaagagaca
    38161 tccaaagtat tttaataagg aacaaataaa ggaaatgtac cataagtctt tataatttga
    38221 ctttacatat ttagttttat ataaaaatta taaattaata ataaaaaatt ataagtaatt
    38281 aatagtaaaa aaattgtgta tagaagttat atatataata aatttgtctt aagcttttat
    38341 tttactttct aataaataaa ggagtttaaa aaagggaaga ttaattaagt aatattttat
    38401 aaaattcttc gatttaaaaa ctttaagtag aggtgaaata aatgtttaat cccaaaagaa
    38461 taatattcga aaaaggaact ttagacactg atgtgggtaa aaaaatatac aataaattta
    38521 gagataataa agatgtagag ataattaata tatcatcaaa taggattaaa gaacatattc
    38581 caggtgaaaa tctatatgaa caatatagaa gtgggaagca gactatggta gttgggatta
    38641 gaaaaagtct gaagtttcaa acatgtaaac cttctgctaa ttatcaacta ccacttgtca
    38701 gtggatgtat gggaagatgt gagtattgtt atttgaacac acaattaggt gataaaccat
    38761 ttataagggt gtttgtaaat gtagatgaaa tacttgaaca gacaaaaaaa tatattgaag
    38821 atagaaagcc acaggtaacc atatttgaag gggcagctac atcagaccca gttccagtag
    38881 agccatatac taattcttta aagaaaacaa tagagttttt tggaagagag gaaaaaggaa
    38941 gatttagatt tgttactaaa tacagtgatg tggatagctt attggatgct gaacataata
    39001 atcatacaga aatacgattt agtatcaata ctcctagaat tataaatgaa catgagcatt
    39061 atacagcctc tgcaaataaa agaatagagt cagctgtaaa acttgctagg gctggttatc
    39121 agattggttt cataatagca cctgtgtttt tatatgaagg ttggaaagaa gagtataaaa
    39181 atctgattat aagtataaaa gaagctttac caaaggattt tgataaaaaa attatatttg
    39241 aagttatatc tcatagatat acaactaaag caaaaaatag aatactagag atttatccag
    39301 atacactatt gccaatggaa aatgaggata gaaagtttaa atacggtcaa tttggatatg
    39361 gtaagtacgt gtatgataaa gaacaattag atgatatgaa agagttcttt cttaaggaaa
    39421 taaatggagt atttaaaaat agtttaataa aatatataat atagcaaatc ttacctaaag
    39481 atttgctata ttttattttt atacatttta tgtttataat aaagcaatga gatttagcac
    39541 tatcatataa gaaaattaaa aagggcacta tctatcaaga acattttttc tagttttgat
    39601 actataaagg ataagagtaa caaaaatatc aggaggagtt atagtatgca tgcatgggag
    39661 tctattcaaa ttacattgga tttaatagaa gcaaatttat cagaagaaat atcaattaat
    39721 gaattagcaa ataaagcaaa tttatcacca ttttactatc aaagactatt taaaagattg
    39781 gtaaataaga ctgtaatgga gtatataaag cttcgtcgtc ttgcaagagc ttctgaatac
    39841 ttagcagaac ataagaatcg tatacttgat gtagctttaa attttggatt tgctagtcat
    39901 gagacattta cacgttcctt taaaaaagca tatggattaa ctccagaaaa atatagagca
    39961 aatccagtaa aactcaatca ctttattaag ccagaattaa ttttaaatta tgctatggtt
    40021 gatgaaggtg ttccactgat tgcagatgat atagtgattg aagtcaatcg taagacattg
    40081 agtaatccaa ggacatttgt tggaatagaa atagaagtac ctatttgcca gttggtgggc
    40141 ggtgaaacaa ctggaattgc aatagtagag gaattatgga tgaaacttgg aagtcaaaga
    40201 cataatatac caaatcaaat tccaggtgga aatgaatttg ctgctcttta tatgggaaat
    40261 gcaaaagaag gaaattgtat gtatatggca ggtgtagagg tagagtcagg tacatcagta
    40321 gaaggatata gtacttttga gttgccagct aaagaatatt tagtatgtgg atttgaggca
    40381 gaaaacttta atgagttagt taattcagct gtttttaaag cagataaatt tatggaaaga
    40441 tggatgaaga aacataattt aacaactact gattttgcaa ttgagatgta ttaccccact
    40501 acacctgaag cagcatatct ggaacattgg attgttccgg ttcctattga acaatagaaa
    40561 ggatgatgaa tatgaattgg caagatgcgt tttttcaaga tactaaacct acatttgagc
    40621 aaattaatga atttattaat aatccattat gggacaagtt aaataaaact ttggtttcta
    40681 cttataatgt agaacctaag cttgaataca gtaaatgttc aatgcaaaga ggttggaatg
    40741 taaaatataa aaaaagaggt aaatcactat gtactttata tccacaagaa ggttatttta
    40801 aagctttggt tattgtaagt gaaagcaata gagtagaggt tgatttattt attaatactt
    40861 gttgtgatta tatcaaaaaa atatataatg aggtaaactt ttttaatgga agtaaatggc
    40921 taatgattca agtagatagt ttattggtat taaacgatat gcttgaacta attaaattta
    40981 gagcttaaca tatagaacag gatgaatata taagtcatcc tgtttttata ttcaatcaga
    41041 taaattaata tatagtctat aatatgaata atttagtaaa tttaaattta ctttatcttt
    41101 ctacattctt tgcaactaag tccacatgtg tttttttctt gcatattagt agcaccccaa
    41161 ttagcaaatt gttgtaaaat aggcacaata cttttacctt tacttgttaa tgtatattca
    41221 acttttggag gaatttcatt atattgttta cgatgaacaa taccagtaga ctctaaatct
    41281 tttaatgatt gagctagcat agtatttgta atgccatcca attttctttt tatgctacta
    41341 tatctaattg gattttcaac tgctaacata catataatag gtaatttcca cttaccaccg
    41401 acaatgtcta atgcataacg gattggacag gttaattctt caacgttttt agttatattt
    41461 ttttcagtat ttatactcat tttaattact ccttagttat agtagtatct tttttatact
    41521 ttatcagaaa aaactgcata cttgtttttt ctgtatttta tattaaaatt atatcaaagg
    41581 ataatcctta atacaagtat ttaaaagggg tgtaagaatt atgaaagcat tagaattttt
    41641 gaacaaggca cgagtttatt atttagcaac agttgatgag aacaatcaag cacatgtgcg
    41701 tcctttagga tttgttatgg aatacaatgg taaacttaca ttttgcacat ctaatcaaaa
    41761 ggatatgttt aagcaactta tttttaatcc aaaggttgaa ctttgttgta tagaccaaaa
    41821 ccttaatact ctacgtattt taggtgaagc agtatttgtt acatcaaaag aaacacaagc
    41881 taaggcactt gaaataatgc caagtttagg tcagatgtac tctgtaggag atggtaagtt
    41941 tgaaatattc tctattgata aggcaaaagt tagttgttgt tcaatgagtg gtaaaaagat
    42001 tgatgtagag ctttaattat aattgaatcg acatccatag tgaaaattaa gaaaacgtta
    42061 ttactgaaat gttgatagat ttaatttaaa tgcaataaaa agatttttaa ataatgaata
    42121 tgtaaaaatt tttagttatt agatgtgtat ttcaataatg atatactatt ttgaataatt
    42181 acatactaga aataagataa ttaaaattta ctttataatg ggatagattt cttttaaaaa
    42241 atattttaac tataattgat ttttatttaa tctgaaaaaa atattatgac tataaaaaat
    42301 tgctacttat tatttggata tttttatata taaataataa gtagcatgac tttataca
//
LOCUS       DAJMZY010000025        42037 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.025, whole genome shotgun sequence.
ACCESSION   DAJMZY010000025 DAJMZY010000000
VERSION     DAJMZY010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 42037)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42037)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42037
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.025"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            126..3672
                     /locus_tag="OE968_001309"
                     /pseudo
     CDS             126..3672
                     /locus_tag="OE968_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453516.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
     gene            3857..5791
                     /locus_tag="OE968_001310"
     CDS             3857..5791
                     /locus_tag="OE968_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgiQ family radical SAM protein"
                     /protein_id="HCP7218597.1"
                     /translation="MENKFLPISKQDMIDRGWEELDFVLVTGDAYVDHHSFGTAIISR
                     VLESAGYKVGIIAQPDWRTTDDFMKLGKPRLAFLVNAGNMDSMVNHYSVSKKHREKDM
                     YSPGGKMGYRPDRATIVYCNKIREAYSDVAIVIGGIEASLRRFAHYDYWSDKVRKSML
                     IDSGADLLVYGMSEKQIVEVANALNDGYDPKYIRHIDGTCYISDTLEEIYDKYILIPS
                     YKEICEDKMKYVEAFKIQYDEQDPFRGNIIVQPHGSKYLVQNKPEKPLSREELDEVYG
                     LPYQKTYHPVYEKFGGIPAIEEVKFSIVSSRGCFGSCSFCAITFHQGRAVQSRSEKSI
                     IDEAIGITNLDDFKGYIHDVGGPTANFRRPACKKQITKGACKNRQCLSPSPCKNLDAD
                     HSEYLHLLRAVRKLPKIKKVFVRSGIRYDYVMADKNNKFLRELIEHHVSGQLKVAPEH
                     ISEEVLKYMQKPAGKTYDKFRQKFFAINEELGKKQYLIPYLMSSHPGSTLNSAIELAE
                     YLRDTHYQPEQVQDFYPTPGTLSTTMFYTGIDPLTMKPVYVPKSKRDKAMQRALLQYR
                     APRNYDLVYSALVEAGREDLIGFGHRCLIKPKNEKPYFNRNNSKKNVSKGTNKNKKTN
                     TNNRSNKNQQKSSTKKKKKH"
     gene            5897..6892
                     /locus_tag="OE968_001311"
     CDS             5897..6892
                     /locus_tag="OE968_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HCP7218598.1"
                     /translation="MKKYISIILLVVLTMVVLVGCSPGKDNPKNKELSVVKQVKVAVP
                     DGLPAVAIAKLANENPEIKEGYETVYSIEKTPEAISTRVMKKDADIAIVPSNMAAIAY
                     NKTSSYNIVGTVGMGSLYLVSTENIKDYSDLVGKEVGCTGKGLTPDITIKSLLLQKDI
                     NYSDIKFNYVNSASELVPLLATGKVKTGIVPEPALSALMSKNPDIKIIKSLNDSWKEV
                     SGSKDGYPQSTLIVKSEFLRDNKDFVDSFVGQLSNSIDWANKNPEELGAYSEKIKIST
                     ESKIIGKSLERANLKYIPVKDMIKDYKNYYEKLANFDDKTLGGKVPDEAIYFVEK"
     gene            6864..7649
                     /locus_tag="OE968_001312"
     CDS             6864..7649
                     /locus_tag="OE968_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HCP7218599.1"
                     /translation="MKQYTLLRNKKNKEQFIDKMEVTLSCVILLFLWQIIALKIDNDI
                     FLPTVGQVFNSIKEIMLNSSFYIDILYSMGRCFFSFLLAMIFAIILSIVSYLNRFFRN
                     LLKPINALTRSIPTMILVVLALIWFEKDSTPFIVGFTIVFPILYDNVLGAILNIDKNL
                     LEMANVYKIRFIDKVLKIYLPAIKFQIISILVSTFSLSLKVAIAGEVYSQPTYGIGTM
                     IQTEKINFNTSGIFAWIIIVLLISAILQIAQKFLARRAFLWKR"
     gene            7637..8335
                     /locus_tag="OE968_001313"
     CDS             7637..8335
                     /locus_tag="OE968_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCP7218600.1"
                     /translation="MEKIKLSIENINKRYDSRIIFRDFNIDFYVNEVNCILGKSGCGK
                     TTLLNIISGIIKNDTNNLNIKENLNRVGNKLEASYIFQDDRLIDWLTVEENIKIVVNK
                     YYNKTQLNKICDEYLELVGISDYKKFYPQMLSGGIRQRVNIARAFIYPSKNIIMDEPF
                     KSIDAKNTQLIMDNFRNILRKEKRTVLFVTHNIEEALFLADRIFILGDSPIRIKKILK
                     NSKELEKNEVLKLI"
     gene            8458..8931
                     /gene="ybaK"
                     /locus_tag="OE968_001314"
     CDS             8458..8931
                     /gene="ybaK"
                     /locus_tag="OE968_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HCP7218601.1"
                     /translation="MVKTNAMRILDSNKIDYKVMSYEVKSEHVDGVEVAHDIGRDVNE
                     VYKTLVTQGVSKNIYVYVIPVHENLDLKKAAKVAKEKSVEMIHVKDINKLTGYIRGGC
                     SPIGMKKLYKTFVNESAKNLDTIIVSAGKIGYQIELSPFDLQRLIKVEFVDVIKK"
     gene            9128..9967
                     /locus_tag="OE968_001315"
     CDS             9128..9967
                     /locus_tag="OE968_001315"
                     /EC_number="4.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate hydratase"
                     /protein_id="HCP7218602.1"
                     /translation="MRKIKSEQIVEQVKKLCIEASLYLGEDVLSCIKEKAKSEKSEVG
                     KNILNILVENAEIAKEKNIPICQDTGMAVFFVEIGQEVLIEGDTLTDAINEGVRQGYE
                     EGYLRKSVVSPINRVNTKDNTPAVIHYDMVKGDKIKIEFAAKGFGSENMSKMKMLKPS
                     DGLEGIKKFIIDTVSEAGPNPCPPMVIGVGIGGTVDKCAQIAKKALFRELGEFNKDEN
                     IAKLESELLTAINKLGIGPQGLGGTTTALGLNIETFPTHIAGLPVVVNINCHASRHKK
                     VVI"
     gene            9980..10528
                     /locus_tag="OE968_001316"
     CDS             9980..10528
                     /locus_tag="OE968_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S-containing hydro-lyase"
                     /protein_id="HCP7218603.1"
                     /translation="MIKITTPVNEIDIAKLNCGDTISLSGILYTARDAAHKRLIDCIN
                     KGEELPFDVYGQGIYYVGPTPTKPGEVIGAAGPTTSYRMDDLTIPLLERGLRLMIGKG
                     KRSDEVIEGMQKYGAVYLAAIGGAGAYISNSIKSCEIIAYEDLGAEAIRKIVVEDLKL
                     TVAIDSYGNNIYEQGRAIYECK"
     gene            10594..11775
                     /locus_tag="OE968_001317"
     CDS             10594..11775
                     /locus_tag="OE968_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent malic enzyme"
                     /protein_id="HCP7218604.1"
                     /translation="MSKDYAKLALEMHEINKGKVSVESKVEVKTKDDLSTAYTPGVAE
                     PCLKIHENQDDVYRYTSKGNLVAVVSDGSAVLGLGNIGAEASIPVMEGKAILFKQFAD
                     VDAFPICLKTNDVDEIVKSVELMEPVFGGINLEDISSPRCFEIEERLKKSLSIPVFHD
                     DQHGTAIIVAAAIINSIKLIENKKIEDLEIVINGAGAAGIAIAKILLNMNVKNIILCD
                     RSGALEASIENLNYVQKEMLKVTNIRNEKGPLKDIIKGKDVFIGVSGPGAVTKEMVES
                     MSEKPIILAMANPAPEIMPEEAKLGGAFIMGTGRSDFPNQVNNVLAFPGIFRGALDVK
                     AKEINEEMKIAAAYAIANTISDEEICPEYILPDVFNKNVVKNVAKAVKEAAIKTKVNR
                     I"
     gene            11943..12329
                     /locus_tag="OE968_001318"
     CDS             11943..12329
                     /locus_tag="OE968_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009248914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCP7218605.1"
                     /translation="MEYKVNDQELNASMFIPFVNRIWPGDYDTDKTQTALSKTLNITA
                     YDDKVLVGCLRVLSDGYYFGTITELLVLPEYQKQGIGSKLFQLAKENTPTMLYFGAQP
                     GVEEFYEKNGCQRSLQSYIIKKKDSY"
     gene            12479..12742
                     /locus_tag="OE968_001319"
     CDS             12479..12742
                     /locus_tag="OE968_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HCP7218606.1"
                     /translation="MEETKFCQCCAMPMGQTDELYGTNKDGSKSTDYCSYCFKDGEFT
                     ADISMEEMIEVCIPHMLQSNKDMTEDEARTMMNNFFPTLKRWK"
     gene            13268..13951
                     /locus_tag="OE968_001320"
     CDS             13268..13951
                     /locus_tag="OE968_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCP7218607.1"
                     /translation="MSSILLVEDDLSLIYGLEFSIQKSGFSIDIARTVKEAMQMYEEK
                     NYDLLLLDVSLPDGNGFQICEKVREVSNIPIIFLTASDEEVNVVMGLDMGGDDYITKP
                     FKLNELISRIKALLRRYNVASNVNELSSNNITIKLLENRVFKGKFEVELTTAEYKLLC
                     LFMKNKNIVLTRKNILDKLWDGNGSFIDDNTLSVYVRRLRNKIEDNPENPKFLLTVRR
                     MGYKWNVIK"
     gene            13962..15203
                     /locus_tag="OE968_001321"
     CDS             13962..15203
                     /locus_tag="OE968_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HCP7218608.1"
                     /translation="MKIFSNKDIKIFFLMLISILVMFIIVGQIVVISITNNYKKTLIE
                     HDYNIAGYLYSIGVDKSKIPSAFVAHEDKYILKGKEILDTAGYGFDIDVSFTPSVKLF
                     QSKYIKTMSIYLLVFFTMIIFILYMYFFRQQSKIEEASYKIDLFMNGNINERLNTYEE
                     GSLSKLFSSIDVMSTSLNTHILKEKQSREFLKNTISDISHQLKTPLTALIMYNQILQE
                     ESHNSDVVEAFVQKSQSELERIETLIKNLLKITKIDSKTIILNKNNVNLKNLIVKILY
                     SFETRAEKEGKVISVNGSENTLLFCDYEWMSEALSNLIKNALDNTKENDKITIEWFET
                     TITTIVSVKDTGNGIHVEDIHHIFKRFYRSKFSKDNQGLGLGLPLVKSIVEQHNGTIS
                     VESKLSQGSIFTISFLKLTNM"
     gene            15275..15958
                     /locus_tag="OE968_001322"
     CDS             15275..15958
                     /locus_tag="OE968_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002574824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCP7218609.1"
                     /translation="MDILVVNNLCKTYGNGYTKVEALKDVSFTVSKGEFVTVVGESGS
                     GKSTLLNLLGGLDTPTSGRIFIDGKEICSMKEEKQTIFRRRNIGFIFQAYNLIPELTV
                     EQNIIFPLLLDYKKPDTIYLDEVLTILGLKDRKNHLPNQLSGGQQQRVAIGRALITKP
                     SIILADEPTGNLDSKNSNDVISLLKVTAEKYNQTIIMITHNTNIASTADRILQVSDGV
                     LTDLGVNRE"
     gene            15955..18285
                     /locus_tag="OE968_001323"
     CDS             15955..18285
                     /locus_tag="OE968_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCP7218610.1"
                     /translation="MRSYLELVPQYAKVHKKKNRTTILCIIIAVCLVTAIFGLADMAI
                     QCQKIQFIKDDGNWHIVIRNIDEKFISEINSRVDIAHHGRGQVVDNGEFKSKEILIQG
                     LDEEVAKQFNLEIIRGRYPIGENETLIDEDAVKSFNLKIGDFIKIKLADGRNKNYKIV
                     GEYSSISSLRATDKHGLILSILGTQAIKKSETYDYYYITFKEKVNIRKATSDIKNTFN
                     LSDKQIGKNERLLSIIGQGDSDFSKPLYLTAGLLFVLVLVASIIMIYNSFNMSVIERV
                     KFFGLLRCLGSSKHQVKKFVVLESLILSIKAIPIGLVLGSLVTIISSIFLKYVNELFS
                     SMPILKVSFIGIAFGIIVGFLTVILSAIIPAKKASRVSPLSAVRGNLMSKEILNNGKT
                     SKVANIGSFKIETSMGLNHAFSRKKSFVLMTSSFAISIILFLGFSVLIDLMYQGLKPM
                     KPEAPHISIVDPNFKSVLTKEDINEISNIKGVKKVYSRMMTDIEATYNGKKTKSQLIS
                     YEKYQFNWAKKYLLKGEVNENKLQSENLALVEEGHGFDIGDKIYIKNGNAEKELEVGG
                     ILSSIPFEAKDKYIGNIITSENTFTNITGIKGYIIMDIQVDKDTPGDLIENIRRVVDD
                     NLEVRDKRQSNLEVKNSFYTMATFVYGFVFIIAIISMFNIINSMNISVTSRKNYYGVM
                     RAVGISNRQLRRMVIVEAGSYAVSGCLLGSILGLILHRYMFISLVSSMFHLEWQVPFN
                     LLLITVLTMIIITLLSVRKPIKKICELDIIDSINAQ"
     gene            complement(18466..19308)
                     /locus_tag="OE968_001324"
     CDS             complement(18466..19308)
                     /locus_tag="OE968_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HCP7218611.1"
                     /translation="MINIGDFNKLTVKRKTEFGYFLDGQTNNTKDDILLHNRLIGKNE
                     INIGDEVNAFIFKDSDDRTAATLIPPLAKVGDVAHLKVVDNTDIGTFIDMGLPKDILV
                     PFKAKTYPLFRDEKYLFYIYLDKSKRIAATTDIDSYLLTDHTYNVGDIVTGVVYGFQT
                     NNSAMICVDNKYAGVILHNEYFTELKTGDVLENLHVIKIYEDGKLGLSPRGNRKDELD
                     TLENKILSYLEGSDGYMRFNDKSDPKDISILFNSSKKNFKRALGVLMKKGLIYQDEEG
                     TYLK"
     gene            19603..20337
                     /locus_tag="OE968_001325"
     CDS             19603..20337
                     /locus_tag="OE968_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCP7218612.1"
                     /translation="MKIVNKSSNIPLHTQLSSIIREMIETGELKEGDAIMPERELCNI
                     QNVSRMTVNKTIVGLVTEGLLYRVQGKGTFVAKQKKKYQFSNVKGFTDVMKEKGVNIK
                     TDILSFEMELPDDLVKRKLGISDNTTNIYKIVRLRYTDGEPFGLEIVYLSEEMCKGLT
                     KGILDNSSLYRVLNEKYGYKIQKAEQVMEPVILSDEESKLLETDEGALALKLHRNSYN
                     REGRPIEYTISIFRTDKYQYEIVLSE"
     gene            20347..21480
                     /gene="nagA"
                     /locus_tag="OE968_001326"
     CDS             20347..21480
                     /gene="nagA"
                     /locus_tag="OE968_001326"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HCP7218613.1"
                     /translation="MKCLINGKIILKNQILENKVLVFDEKIIDIADSVPKDCEVIDAD
                     GKYISPGLIDIHIHGNMGKDTMDSTDESIETISKSIMRHGVTSFLPTTMTMDKEHVYD
                     ALEVIKKAQNRKLEGAQVLGAHLEGPFINENYKGAQNEKFIINSKYEFIKEYKDVIKV
                     ITYAPEKDIDFDFTREIKRCTDIVLSIGHSNANYDQAKEAINLGVTNVTHMFNAMTGL
                     NHRDPGVVGAALTTNVYSELIADTIHINKDLFQFILNNKGKERLILITDSIEAGGLED
                     GNYSLGGQKVIVKGNEARLENGALAGSVLSLNKMVFNFLNNTNLKVNEAINLASLNPA
                     TSLGINDKKGSLEIGKDADIAVFDENLDCKMTLCLGEVVYKNI"
     gene            21579..22337
                     /gene="nagB"
                     /locus_tag="OE968_001327"
     CDS             21579..22337
                     /gene="nagB"
                     /locus_tag="OE968_001327"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012425552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HCP7218614.1"
                     /translation="MRVLVCKDYDGMSKKAAEMIAAQIVLKPNSILGLATGSTPVGMY
                     RDLVKKYNDNIVDFSDVMSFNLDEYYKLPISNDQSYDYFMKENLFNHVNIKPENTHLP
                     NGMADDIEKECMNYEASIDAAGGIDVQVLGIGRNAHIGFNEPDTKFAKRTHVVELTES
                     TIEANARFFKSREDVPKKAVSMGIGSILKSKKILLLASGEEKADAVYNTVYGDITPEV
                     PGSILQLHKDTIVIVDEAAASKLNPKDYKLVIIV"
     gene            22393..22665
                     /locus_tag="OE968_001328"
     CDS             22393..22665
                     /locus_tag="OE968_001328"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218615.1"
                     /translation="MLKIIMFSGILSSIIKLPIIGILPTGNIKKNTGISDSKKDGKQR
                     RSNLGISIYQLPSFLYSLINNSVPSNKPIPPEEIKLIKMYLLKSCI"
     gene            23325..24029
                     /locus_tag="OE968_001329"
     CDS             23325..24029
                     /locus_tag="OE968_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCP7218616.1"
                     /translation="MSKLIYIADDEDNIRNLVKTFLKNEGHDVMDFKTGDELLEQFNI
                     KECDLVILDIMMPGSSGFEVCTKLREKSTVPIIMLTARDTDIDYITGITLGSDDYFTK
                     PFSPMSLVMRVKSIFRRIEFEKKQNYDKYSNSIDMELKFGDVIINKKNKIVTSKNVNI
                     DLTPNEYNLLTYLFENIDRAISRDELLNKIWGYDIEVETRAADDTVKRLRKKILDTNI
                     LIETVWGFGFRLKEKS"
     gene            24031..25518
                     /locus_tag="OE968_001330"
     CDS             24031..25518
                     /locus_tag="OE968_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HCP7218617.1"
                     /translation="MKNGNDKNRIGKIKSKFKLKFSKKNISIKTRILLSILCLIIIVF
                     MIILVSFNVFLDTYIKTTANEELTKSTEIVEHMDSNFRPIKPPQDDGKLPPKVLSNFM
                     RNVQDKVRMAETQSDADAMVVDSKYNLIFPTREDDFLKNVDEMELIRECIQNEKLDLN
                     SDANTRISTRNKDYYISTVKITSIYGEQDKYLILFIDISKTLNLAQKINIVLISVMCF
                     AGILAIFTAVILSEKIAKPIKELCEFAKKMGQGDFKRTYFDFSDKELVELSTVMNKSA
                     EYLDKYDNEQKIFFQNASHELRTPLMSIKGYAEAIKYNVIDSKHASDIILEESDRLSD
                     MVEDLLYISKIDNITKDFELVECDLREVLSNCGARQNVRAINKGIKFIYEFDEEMVLF
                     ECDEKNISKAFMNLIENALRYAKSEIKIVCKYNQKNIVVIIEDDGIGIKKEDLPHVFE
                     RFYKGVGGNHGIGLSIVKSIVNKHGGRIYVENGKKGAKFTILFKL"
     gene            25723..27336
                     /locus_tag="OE968_001331"
     CDS             25723..27336
                     /locus_tag="OE968_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HCP7218618.1"
                     /translation="MKEQLIFNITNLVTVVFEAFVIHMFLSDFLGQKEGYIKVVRYAK
                     LGFIICLGFCNLITLNPKITMPLIFILIFSTSFLYKGNLKTRLFTTVLLSIFFILSEI
                     VVTSIFVLFVKEGFEIMLENNSIRVLATILSKIVFLLTCKIICLFKKDVHLDMPIKYW
                     LPLFLIPIFSLFLSVSIFDVSKFFSLESLKFLSLISSVGILYINFIVFYLFKFIIDKT
                     KLSMKYELLEKEIIHKEELRLSNECYKIIVEQTDSVVFEWNIKENKSFVSQAWTEKFG
                     YNNACKNIFKEIKDKDLVHSEDKAIFEGFLESIKKKNMHNQAVYRLKKSNGEYIWCRT
                     SITSIYNDENELLRVVGVIVDVDSDIKKYEELRTRAESDSLTNIYNKGTFEKLVEETI
                     VMNTGDKKDALFIIDLDDFKEINDNFGHPFGDFVLKTFADKIQTSFGSKDLVGRIGGD
                     EFVVYMQDYVTEVNLHKKAKELNRVLSDNYTDLSFSFDASVSIGIARYPQDGTSFFEL
                     FKNADRALYSIKASGKNSYCLFEEELYVQ"
     gene            complement(27699..28529)
                     /locus_tag="OE968_001332"
     CDS             complement(27699..28529)
                     /locus_tag="OE968_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HCP7218619.1"
                     /translation="MSQVSKNYFTTGEFAKICGINKKTLFHYDDIGLFSPELKKENGY
                     RYYSYHQLSIFGIISSLREVKMPLKEIKAYIDKRTPNLLIELLEKKTIDIKNEIEKLN
                     NIQALMESTISFTKNACNIDANTITLKEHEEEYLVKTPVTYKEQFLGDEEENFLYECI
                     NFMDNYELSDYGTIGSIIKGEDIINKDFESYSYLFTKVNKEYKKYPVSIKPKGLYVTA
                     YHKGSYETIYKAYEKLLNFFNQNNLRIGDFVYEEYLLYDISVRDSNEYLTQISAEVKM
                     "
     gene            28602..30329
                     /locus_tag="OE968_001333"
     CDS             28602..30329
                     /locus_tag="OE968_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCP7218620.1"
                     /translation="MKKLIHFLKPYRVLIVVVLIFTFLQTLGTLYIPTLTANIVNNGV
                     VKGDIDYIVKTGLMMMIVAGITALSAVLVCKVSANLSSGFCRDIREAVFIKSQDLSIN
                     DFNNIGTASMITRSTSDITLIGQSVFMFIQLVLPAPIITVSGLFLAYSIDKAMTIIIV
                     VVMFLFMLSAFLVGKKLIKLFKMMQIKMDNMNRVLREVVTGVRVIRAFNRSHFEKKRF
                     DRTAIDYSETAISINKIFAVLMPIVMLIMNLGIVSIIWFGGMRVSNGNMEIGHIMALV
                     EYCILILFYLIMGVMVFMYIPRAGACADRVNQILDIEPEIVDGNGHKDTVSERGHLVF
                     KNVTFSYAQSEEPVLNNITFEAKSGEVTAIIGSTGSGKSTIANIIPRFFEIQSGEISI
                     NGQDIKKIPQKELRDKIGFVPQKAFLFSGTIEENIRYGKEDASIEEVKHAASIAQADE
                     FISDMEDKYDSFVAQGGNNLSGGQKQRISIARALVRKPEVYVFDDSFSALDFKTDKRL
                     RKALKNEIKDSSAIIIAQRISTIMDANQIIVLNDGKIVGIGKHKDLLENCEVYKQIAD
                     SQLSKEELA"
     gene            30366..32228
                     /locus_tag="OE968_001334"
     CDS             30366..32228
                     /locus_tag="OE968_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCP7218621.1"
                     /translation="MSEKRIDEQDIEVLSFEDGMSAEKAKDAKKTTKRLLKYMAKQKF
                     KILIIFISVLISSALTVLAPMVMGKAIDQLFNGIKTAVQTGTKFSVNFSTMGGIVSIL
                     LGLYLISAVFIYIQQYIMSGVAQNLVLSMRKDLSDKLNKLPLKYYDSHKKGETLSIVT
                     NDLEKVADSLQEGLMQLITAVVTVVGSIVMMISISVPLTIVSAITLLVSLGITVVIAR
                     KSQERFSENQKALGELNSNIEEIFTGQIVVKAFSKEKDTIRNFKILNQNLYNASRKAQ
                     FSSYAISPIIRFINLIGYVIIAVVGGIFASTGAMTLGSIQAFIQYVNQASEPTTEISY
                     IVNMLQAAIASAERVFTVMDEVEEIKDEESSKVISMPKGKVQFEHVKFGYSDDFILMK
                     DININLNAGDKIAIVGPTGAGKTTLVNLLMRFYEIQGGRITIDGVNIKDLKRGELRTM
                     FGMVLQDTWLFNGSIKENIAYSKSDATMDEIVRAAKSARVDHFIRTLPQGYDTILTED
                     ASNLSQGQKQLLTIARAILSDPSVLILDEATSSVDTRTEVEIQKAMNNLMKGRTSFVI
                     AHRLSTIRDADLILVMKEGTIIEQGSHKELIEKKGFYEELYNSQFTSEYDEDVV"
     gene            32561..33250
                     /locus_tag="OE968_001335"
     CDS             32561..33250
                     /locus_tag="OE968_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyphosphate polymerase domain-containing
                     protein"
                     /protein_id="HCP7218622.1"
                     /translation="MNKKLNYRFEMKHKITEADVLALKSRLYQIMKKDENASKDGKYL
                     IRSLYFDTPEDKALLDKLNGVAIREKFRIRFYNNDCSYIRLEKKIKHYNMTSKLSTNL
                     TKKEVINILNNDIEFLKESTNCLLREFYLKLKCERLEAKSIVDYNREAFIYPVGNVRV
                     TIDSDIKTSVNSVDLFNKDLPTVSVIDENMTVLEVKYDEFIPDFIKDLIQINKTTSTA
                     VSKYASSRLYI"
     gene            33355..34041
                     /locus_tag="OE968_001336"
     CDS             33355..34041
                     /locus_tag="OE968_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4956 domain-containing protein"
                     /protein_id="HCP7218623.1"
                     /translation="MILIMTFNDIFKSSFIENVSGFSFVDSALALGSAFLVGLFIYMV
                     YKKTYMGIMYSRPFNVSLVALTMLTTFVILAVTSNVVLSLGMVGALSIVRFRTAIKDP
                     MDLVFLFWSLGSGIVLGAGLIPLAVMGSIIMGLILIFFSNKTISETPYILMVNCNNED
                     SEDIATDKIKKVFTKYQIKSKSVTPEKGIELVFEVRMKDGETSLINDLSQVDGVTNAV
                     LVSYNGDYVA"
     gene            34058..35965
                     /locus_tag="OE968_001337"
     CDS             34058..35965
                     /locus_tag="OE968_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CotH kinase family protein"
                     /protein_id="HCP7218624.1"
                     /translation="MKDKKFTLLISIMIIFLCAVVGVYSTSSNKSVDLYSDVYIEKYF
                     NRDKVMEVNIEIDESDLKDMNENAIKEEFKVAKVTVDGDTYGNVGIRTKGNSSLISVA
                     NSDSDRYSYKINFDKYNTSQSMEGLTQLNLNNCYSDPSYMREFLTYSICEEMGLATPE
                     FAYAKVSINGEYHGLYLAVEGLKESYLENNFGNVTGDLYKSDEGSSLQYKGDDPESYS
                     NLIVESDKKTADWSKITKLLKSLDTGEDIEKYLDVDSVLKNIAINTALLNLDSYQGSF
                     AHNYYLYEQDGVFSMLPWDFNMSFGGFSGFGGGSQSIAIDEPTTGNLEDRPLISSLLK
                     NETYKTKYHKYLEEIVTKYLDSDYLENMTTKLHDMIASYVKEDPTAFYTYEEFEKNIT
                     SSIEDSSDNKGFGNKGFDNNNSNNSDSNNNSNSENKRSGNQSDEKEVNAELTSSVVKA
                     NTDNETKNKTTNDSESKNNTDKDKSGNDNNQKLEGPMGKGGKSIPGVLEVAEDMSKTI
                     KSQLSGETSSTKQNSGDESSSGIKGSEKFDEDMSGMPEPPEGMDGKMPPGMGNMDKGD
                     MNGKNGNMNMDRNQDNPIEVGGFGNRGGGSVSKTTTYFKLILGGASMIIMSIMLVGVS
                     RVKRRRFIKSK"
     gene            36416..37105
                     /locus_tag="OE968_001338"
     CDS             36416..37105
                     /locus_tag="OE968_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218625.1"
                     /translation="MLQKVLWKFLKLVVGLFICSVGIVLTINCNLGLSPWDVFHQGLS
                     NHIGITIGTASIIVGSIVVIADVVLGENVGWGTVFNMLLIGFFMDLLLYSNLIPEADN
                     LFVGIIMLILGLVLLSVGMVFYMGSGLGSGPRDGLMVAIQKKTGKSLKLIRGTIEVGA
                     LIVGFLLGGKVGIGTIISAFGLGYFTQMVFGLFKLDCSKIKHRFIVDDIKFIKVYMSG
                     EKKAAVQNIVK"
     gene            37541..38080
                     /locus_tag="OE968_001339"
     CDS             37541..38080
                     /locus_tag="OE968_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007286148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCP7218626.1"
                     /translation="MDIGEKIKRLRTEKQLTQEELANRCELSKGFISQLENNLTSPSI
                     ATLIDILEILGTNLREFFNEIDDERISFTKEDMFETEDEDLKYKLKWLIPNSQKNEME
                     PIIITLYPGGQYKEEKPHEGEEFGYVLAGSIYVHIGEKKNKVKKGESFYFRPKANHYI
                     SNEGKTTAKVIWVSTPPSF"
     gene            38099..39142
                     /locus_tag="OE968_001340"
     CDS             38099..39142
                     /locus_tag="OE968_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011721317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCP7218627.1"
                     /translation="MVENIIELRDISKHYEELTVLDNFNLDIKKNEFLTLLGPSGCGK
                     TTTLKIIAGFEYADDGKVLFEGKEINNLPPYERQVNTVFQKYALFPHMDVYENVAFGL
                     KIKKTPKDVIDAKVKEVLKLVALEGFERRQVESLSGGQQQRIAIARALVNEPKVLLLD
                     EPLGALDLKLRQEMQIELKRIQKKLGITFVFVTHDQEEALTMSDTIVVMYKGKIQQMG
                     TPQDIYNEPKNSFVAKFIGESNIFDGIMIEDYKVNFCNRDFECVDKGFEKNENIEVVI
                     RPEDIKMVKPEEGMLKGKVTSTVFKGVHYEIELNENGRLWILHNTKNAEVGTELGMDI
                     YPEDIHIMRKENN"
     gene            39144..39980
                     /locus_tag="OE968_001341"
     CDS             39144..39980
                     /locus_tag="OE968_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCP7218628.1"
                     /translation="MKRKSFLAYPYVVWSAIFVIIPLILVVFFSFTKESGGGYAFTLE
                     NYKEVIDPIYMKVFGRSILLAGGATLICLIVGYPVAYIISKARVSRRGSLILLFILPM
                     WMNFLLRTYAWVAILGKNGLLNTFLGWFGIQPLAILYTNFAILLGMVYNFLPFMVLPI
                     YTALSKMDNDLINAAHDLGANNMTVFRKIIFPLSLPGVMSGITMVFMPAVTTFAISRL
                     LGGGKIMLVGDLIEQQFTVVGDWNFGSAISIFMMIVILISMSIMSKFGDESDKEGGGL
                     LF"
     gene            40085..40759
                     /locus_tag="OE968_001342"
     CDS             40085..40759
                     /locus_tag="OE968_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCP7218629.1"
                     /translation="MARWNGFTWKWYGQLLQNESIMSALYYTIVIAILASVISTIVGT
                     ISAIGIHKMRGKSKKLILNVNYLPILNTEIVTAVALMSLFVFVKMEFGFTTMLLAHIM
                     FCLPYVILSVLPKMKQLPDNIEDAAMDLGATPIYALRKVILPQIKPGIVSGFLIAFTM
                     SIDDFIISFFNAGNGVSNLSIEIYGMARRGIKPEINALSTIMFAVVLGLLLLANKKES
                     IVRGIK"
     gene            40759..41811
                     /locus_tag="OE968_001343"
     CDS             40759..41811
                     /locus_tag="OE968_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine/putrescine ABC transporter
                     substrate-binding protein"
                     /protein_id="HCP7218630.1"
                     /translation="MIKFKKAISLIAVGMMTVTLFTGCNKATDSTKVLNVYNVGDYID
                     ESLIDKFEKETGIDVQYSTYDTNEMMYQKVKSGSTHYDLVFPSDYMVEKMKNEGLLEK
                     LDFKNIPNMKYLDKSFLNPVYDKTNEYSVAYMWGTLGILYNKKEVKDPMDSWNILWNP
                     KYKGNIMMFDSVRDTIGITLKKLGYSMNSVNPKEINEAKNLLMKQKDLVLAYVNDEGK
                     DRLLGGEVAMGMLYSGDAVTLMEQNPDLDYAIPKEGTNKWVDAMCVPTTAQNKKEAEL
                     FINFLLDPENAKVNAEYIGYSTPNTGALKLLDPEITQNPVAYPSKEVLDKCETFEDIG
                     ENIKLYDKAWIELKSK"
BASE COUNT        16550 a         4376 c         7377 g        13734 t
ORIGIN      
        1 taattctaat acaggaagaa ggtaaatgta tattgaaaaa atcatagaaa tagaagtaaa
       61 caatttaaat aaatacaaag gtttgcaaaa gaagtaatat aattatatac aatgaggatg
      121 tgagtatgat gaacagacta aagccaagaa ttttaggtat tagtatcttg tttattatta
      181 taattatttt aacatgtgga gctgttttca agtttaaatt taaattagat aataaattaa
      241 aagaaaccac acatacatat ttgtctgagt ttacagaaca caatataatt aatctcaaga
      301 caagacttag tggtcaattt gacatgcttg aatctattgc taacttcata ggaaacttga
      361 ataatataaa tgatgaaatg gtgattgatt taatggattc tgatgtaaag cgaagttctt
      421 taattagaat gactatctct acattagatg gggaatgtta ttctaatgat ggaattaccc
      481 ataatgttca agatagagat tattttaaaa aagctaaaaa tggagaaaag aatatatcag
      541 agcctttaaa atctattgtt aataataaag aaataatagt tttatctacc ccagtttata
      601 aaagtgggaa aatagttggt gttttaagtg gaatttatga ttcaaaaaag ttaaatgaat
      661 tattaggatt atctgcattt gatgaaaaag cagatgtttt tgttgcaaag aaaaatggag
      721 atataattgc tcaaaaaaca aataaaaata gtaagacgat atcatgtata tttcagcttt
      781 ttgacaaaga taattgtgat gaagttgatt gtctaaaaac tataaaagaa aatatgaaaa
      841 atgataagtc tgagtatttt aattataact tagataatga aaaatttatg ttaaactatc
      901 agccacttgg agttaatgat tggtatgttt tttctgttgt gccaaataaa atagtgtcta
      961 ttcagtcaga gaatatatct tatgatgtat atatttttgc atgaaatact actagttata
     1021 ttaattttta taatatatat agcatgtatt ataaataata acaccaaaat tattataaat
     1081 gaaaaagaaa aatttaaagt actcactgat aatatactag gaggggttaa aacctgttta
     1141 aaagatgaat atatgactat gacatatgta agtcaggggt ttttagagct tacaggttac
     1201 tcttgtgaag atttaaataa aatatttaaa aatagattta aagacatgat ttataaagat
     1261 gatttagaca agtttaattg tattattcta aaccaattag aaaaacaaga taaaattgaa
     1321 gttgaatata gaattgtaag aaaagatgga agtataattt ggattttgga gagaagtaag
     1381 tctataaatg ataataaagg aagtgagtgt attcagggag ttttaactga tataacagaa
     1441 tttaagaaaa tacaagaaga gttagattca aaaagatttg aaatacaggc tatcaatgat
     1501 agtattgttg gtggaatagt gataactgag ataaatgatg attttgatag tatatattta
     1561 aatgaaggtt atttaaatat gattggatat acacgcaaac aactgaaaga tgagctaaat
     1621 aataaattaa tcaaacttat ttttaaagat gatagaacag aattaattaa tagtataaac
     1681 aaacaactca aattaagtga tacatttgca tctgaacaaa gagttgaaaa aagggatggc
     1741 actattatat ggattttatt aaaaggaaga aagatgattt atgataatgg aaaatctgta
     1801 ctttgttgtg ttattgtaga tattacttct gctaaattat tagagcaaga acttaaaaag
     1861 agtgaagaac gtcatgaaat cattctaaag cagacgcaaa atattataat agaatgggat
     1921 atagaaaaag ataaaatgaa tatatcacct aattggtata ataagtttaa atatgaccct
     1981 ataactgaaa acgcaacaaa aaatataatt aaatcagtag atatatatca tgatgatatg
     2041 gataagttta tttcattaat taaacttact tcacaaggta gtgagtatga agagtgtgaa
     2101 attagactta gaactagaga tactatttac gcttggttta gtataaaggc aacaacttta
     2161 tttgataata atggtaaacc ttataaagta gtaggaagtt tgactgatat tgatgaatca
     2221 aaacgagaag ctgaaaagtt gaaagaaagg gcagaaaaag accctcttac agatttgtat
     2281 aataaaaaag catcacaatc acttatagaa gagtacataa cattggataa aaaaagaaaa
     2341 ggtgctttaa tgattattga tattgatgac tttaaaggaa taaatgataa tttaggacat
     2401 ttatatgggg atgctgtatt aagtgaagtt gcaaatgacc taataaatct atttagagca
     2461 accgatatag taggcagaat tggtggagat gagtttattg tatttataaa agatatttct
     2521 aaaacaagag atattataaa taaagcagaa gaattggtaa aaacatttga aaggtctttt
     2581 ttaggtaaag gacgaaatta taaaatatca ttaagtgtag gaattgctaa gtttccacaa
     2641 gatggtatgg actatatgac actatttaga aatgcggata tagctcttta ctcagccaaa
     2701 gggaagggca agaattgtta tacattgtat gataaaaaaa ttgataaagt ccaatatata
     2761 actaatacaa gaaatgcagg agatagtgat aatgtagaga tgtcttttaa agaacatatc
     2821 acaaattata tatttgatat actatatgaa tcaagtgata tagaagtggc agtaaattta
     2881 attctaagta ttgtaggtaa acactttaat gtgagtcgca tgtatatatt tgaaaattca
     2941 gatgataatc gagtatgtaa aaatacattt gaatggtgta acgaaggtat aacctcggaa
     3001 attaataatc ttaaaaatat ttgttacaag gatttaggca actatctttt aaattttaat
     3061 gcagatgggt tattttattg taatgatatt gaaaatttag gtagtgatgt gaaaaaagta
     3121 cttaagccac aaggcatacg ttcaatatta caatgtaaaa ttttagaggg taatgaattt
     3181 agagggttca taggatttga tgaatgttca tataatcgta tgtggactaa tgatgaagtg
     3241 aacactttga catttatatc taaaacgctc aatatgtttt tattaaaaat gcgtattcag
     3301 agtaagctag aagagtcttt aacaattcaa aaatctgtga tggataatat ggatatatgg
     3361 gcatatgttg ttgacaggaa tacctatgaa ttactattta tcaataaaaa aatgcttgag
     3421 tcagcaccaa acactcatgt aggtgattta tgttataaag cgatatggaa taatcaagat
     3481 aaaccttgta aaaaatgccc tatgatatat ttaaaagatg gtgatgatac ttataaatca
     3541 ttcatgcata ataaaaagtt tgaggtacag gcaaatataa ctacaactac tttgaaatgg
     3601 tttgatggta aagatgcatg tttaatattt ggaagtgaaa taactagtat tgaagctgaa
     3661 gaaaatactt aaaatactgt gttatatata tacttaaaat cgcaatttga atttattaga
     3721 cttaaaatgt ctatataaat catttaagtt gtggttttaa gtatttttta tgatataatt
     3781 aagcgttaag aacaaaatta aaagatactt ttgtataaaa aaatatttgt taaatatata
     3841 ttgagcaggt gataatatgg aaaataagtt tttaccaata agcaaacaag atatgataga
     3901 tagaggatgg gaagaattag attttgttct agttacagga gatgcttatg tggaccatca
     3961 tagttttgga acagcaataa tatctagagt tttagaaagt gctgggtata aagttggaat
     4021 aatagctcaa ccagactgga gaactacaga tgattttatg aagctaggaa aacctagact
     4081 tgcatttcta gttaatgcag gaaatatgga ttcaatggtc aatcattatt ctgtaagtaa
     4141 aaagcataga gaaaaggata tgtattctcc aggtgggaaa atgggttata gaccagatag
     4201 agctactata gtatattgca ataaaataag agaagcatac agtgatgttg caatagtaat
     4261 aggtggaatt gaagcgagct taagaagatt tgcacactat gattattgga gtgataaggt
     4321 tagaaagtct atgttaatag atagtggagc agatttatta gtttatggta tgagtgaaaa
     4381 gcagattgta gaagtagcca atgcacttaa tgatggatat gacccaaaat acattagaca
     4441 tattgatggg acatgctata tttcagatac attggaagaa atatatgata aatatatatt
     4501 aattccatca tataaagaaa tttgtgaaga taaaatgaag tatgtagaag cttttaaaat
     4561 tcaatatgat gagcaagacc catttagagg taatataatt gttcaacctc atggaagtaa
     4621 gtatctggtt caaaataagc cagaaaaacc acttagtaga gaagaactag atgaagtata
     4681 tggattacca tatcagaaga cataccatcc tgtgtatgaa aaatttggag gaataccagc
     4741 tatagaagaa gtaaaattta gtatagtaag ttcaagaggc tgttttggta gttgttcatt
     4801 ttgtgcaata acatttcatc aaggtagagc agtgcaaagt agaagtgaaa aatcaattat
     4861 tgatgaagca ataggaataa caaatttaga tgattttaaa gggtatatac atgatgttgg
     4921 aggtccaaca gctaatttta gaagaccagc atgtaaaaaa caaattacta aaggtgcttg
     4981 taaaaataga caatgcttat ctccatcacc atgtaaaaat ttagatgcag accacagtga
     5041 atacttacat ttacttagag ctgtaagaaa attacctaaa ataaaaaagg tgtttgtgcg
     5101 ttctggaatt agatacgatt atgtaatggc agataagaac aataaatttc ttagagagtt
     5161 gatagagcat catgtaagtg gtcagttaaa ggtagcccca gaacatatat cagaagaagt
     5221 tttaaagtat atgcaaaaac cagcaggaaa aacttatgat aaatttagac agaaattttt
     5281 tgctataaat gaagaattag gtaaaaagca gtatttgata ccctatttaa tgtctagtca
     5341 ccctggttct accttaaata gcgctataga gttagcagag tatttaagag atactcacta
     5401 ccaaccagag caggttcagg atttttatcc aactccaggg actctatcta caaccatgtt
     5461 ttatacaggt attgacccgc ttacaatgaa gccagtttat gttcctaaat caaaacgtga
     5521 caaggcaatg caaagggctt tattacaata tagagcacct agaaattatg atttggtata
     5581 ctctgcgtta gttgaagcag gaagagaaga cttaattggt tttggacata gatgtcttat
     5641 aaagccaaaa aatgaaaagc cttattttaa tagaaataat tctaaaaaaa atgtatctaa
     5701 aggaacaaat aaaaacaaaa aaactaatac aaataacaga agtaataaaa atcaacaaaa
     5761 aagttcaact aaaaaaaaga aaaaacatta aagtataaat aaaaatactt aaaaaagaag
     5821 gattattcga taaattaaca gaaattagta taaataaata taattatttt aatgacgtta
     5881 cctttgggag gaagagatga aaaagtatat ttctataata ttattagtgg tgttgactat
     5941 ggttgttttg gtaggatgtt caccaggaaa agataaccct aaaaataagg agctatcagt
     6001 tgtcaaacaa gtaaaagtag ctgttccaga tggactacca gcagtggcaa tagctaaact
     6061 tgcaaatgaa aatccagaga ttaaagaagg atatgaaaca gtgtatagca ttgaaaagac
     6121 acctgaagcg atttccacta gagtgatgaa aaaagatgca gatatagcta tagttccttc
     6181 aaacatggct gcaatagcgt ataataaaac ttcatcatat aatattgttg gaactgtagg
     6241 aatgggttca ctttatttgg tgtcaacaga aaatataaaa gattactctg atttagttgg
     6301 taaagaagtt ggatgtactg gaaaaggact tactccagac ataactataa aaagtctttt
     6361 gttacaaaag gatataaatt attcagatat aaaatttaat tatgtaaatt cagcaagtga
     6421 actggtacca ttattggcta ctggtaaagt taaaacaggt attgttccag aacctgcact
     6481 tagtgctttg atgtctaaaa atccagacat aaaaattata aaaagtttaa atgactcatg
     6541 gaaggaagta agtggttcaa aagatggtta tcctcaatct actttaattg taaagtctga
     6601 atttttaaga gataataaag attttgttga ttcttttgta ggtcaattat caaatagtat
     6661 agattgggca aacaaaaatc ctgaagaatt aggtgcatat tctgaaaaaa taaaaatatc
     6721 tactgaatca aagataatag gaaaatctct tgaaagagct aatttgaaat atattccagt
     6781 taaggacatg attaaagatt ataaaaatta ctatgagaaa ttagctaatt ttgatgataa
     6841 gacattagga ggcaaagtac cagatgaagc aatatacttt gttgagaaat aaaaaaaata
     6901 aagaacaatt tatagataaa atggaggtaa cactttcttg tgttatcctc ttatttttat
     6961 ggcaaattat tgctttaaaa attgataatg atattttttt accaacagta ggtcaagtgt
     7021 ttaatagtat aaaagagatt atgctaaatt ctagtttcta tatagatata ctttactcta
     7081 tggggagatg tttttttagt tttttactgg ctatgatttt tgctattata ctttcaatag
     7141 tgtcttattt aaatagattt tttagaaact tattaaagcc aatcaatgct ttgacacgtt
     7201 caataccaac tatgatattg gtagtacttg cacttatttg gtttgaaaag gatagtaccc
     7261 cttttatagt tggatttact atagtttttc ctatattgta tgataacgtt ttgggcgcta
     7321 tattgaatat agacaagaac ttattagaaa tggctaatgt gtataaaata aggtttatag
     7381 ataaggtgtt aaaaatttat ttaccagcca taaaatttca aattatatct atactagtat
     7441 caacattctc tttaagtttg aaagttgcta tagcaggaga ggtatatagt caacctacat
     7501 atggtattgg aactatgata cagactgaaa aaattaactt taacacatct ggaatatttg
     7561 catggataat tattgttctt ttaatatctg ctattttaca aatagctcaa aagtttttag
     7621 caaggagagc ttttttatgg aaaagataaa gttgagtatt gaaaatataa ataaaagata
     7681 tgatagtcgt attatattta gagattttaa tattgatttt tatgtaaatg aggtaaattg
     7741 tatccttgga aaatctggtt gtggaaaaac tacactcttg aacataataa gtgggattat
     7801 taaaaatgac accaacaatc taaatatcaa agaaaattta aatagagtag gaaataagct
     7861 tgaagctagt tacatatttc aagatgatag acttatagac tggttaacag tagaagaaaa
     7921 tataaagata gttgtaaata aatactataa taaaactcaa ttaaataaaa tttgtgatga
     7981 atacttggaa ttggttggaa ttagtgatta taaaaaattc tatcctcaaa tgcttagtgg
     8041 aggtattaga caaagagtaa atattgctag agcttttata tatccatcaa aaaacattat
     8101 aatggatgaa ccttttaaat ctattgatgc aaagaataca cagcttataa tggataattt
     8161 cagaaatata ttaagaaaag aaaagagaac tgtgttattt gtaactcata atattgagga
     8221 agcattgttt ttagcagata ggatatttat tttaggagac tctccaatta gaataaaaaa
     8281 aatattaaaa aattctaagg aattggaaaa aaatgaagtt ttgaagttga tatagagtta
     8341 taataatact gtcgttttaa aatatatttg gttaaaatct ataagactat attaaaatag
     8401 tacagaatat tcaaaactgt gtataatgtt cgtattttat aaaaaggaag tgaatgtatg
     8461 gttaagacta atgctatgag aatattagat tcaaataaga ttgattataa agtaatgtct
     8521 tatgaagtga aaagtgaaca tgtggatggt gttgaggtgg cacatgatat aggaagagat
     8581 gtaaatgaag tgtataagac attagtaact caaggagtta gtaagaatat atatgtatat
     8641 gtaataccag tacatgaaaa cttagactta aaaaaggctg caaaagtagc taaagagaaa
     8701 agtgtagaga tgattcatgt aaaagatata aataagctta caggttatat tagaggcgga
     8761 tgttctccta taggtatgaa aaagctttat aaaacttttg taaatgaaag tgcaaagaat
     8821 ttagatacaa ttattgtgag tgcaggaaaa ataggatatc aaatagaact atctccattt
     8881 gatttacaaa gacttataaa agtagaattt gtagatgtaa taaaaaaata agaattacat
     8941 ataaaatata gagcttatat tctcaataat aggtgttgta atattaataa aatgaataat
     9001 aattttaaaa taaatattca gttacttatg tgtaattggt ataaaaatat tgagaaattt
     9061 taaaaacaat ggtaaagtgt aagtataatc acgaatattt tttataaagt aatggaggga
     9121 tgttcgcttg agaaaaataa aatctgaaca aatcgtcgag caggtaaaaa aactttgtat
     9181 agaagcgagc ctatatttag gagaagatgt tttaagttgt ataaaagaaa aagcgaaaag
     9241 cgaaaagagt gaagttggaa aaaatatatt gaatatatta gttgaaaatg ctgaaatagc
     9301 taaagaaaaa aatataccaa tatgccaaga tactggtatg gctgtatttt ttgttgaaat
     9361 aggacaagaa gttttaattg aaggagacac acttactgat gctataaatg agggagtaag
     9421 acaagggtat gaagaaggct acttaagaaa atctgttgta agtccaatta acagagtaaa
     9481 tacaaaagat aatacacctg ctgttattca ttatgatatg gtaaaaggtg ataaaattaa
     9541 aatagaattt gcagctaagg gatttggaag cgaaaatatg agtaagatga aaatgttaaa
     9601 gccatcagat ggattggaag gaattaaaaa attcataata gatacagttt cagaagctgg
     9661 acctaaccca tgccctccta tggtaattgg agttggtata ggtgggactg tggacaaatg
     9721 tgctcaaata gctaaaaagg cactttttag agaactaggt gaatttaata aggacgaaaa
     9781 tatagcaaaa cttgaaagtg aactattaac agctattaat aaacttggta taggacctca
     9841 aggcttaggt ggtactacaa cagctttggg attaaacata gagacttttc ctacacacat
     9901 agcaggtcta cctgttgttg taaatataaa ctgccatgca tcaagacata agaaggtagt
     9961 aatttaggag gaaaataaaa tgataaaaat aactacacct gtaaatgaaa ttgatatagc
    10021 aaaattaaat tgtggagata caattagttt gagtggtata ctttatacag caagagatgc
    10081 tgctcataaa agattgatag attgtataaa taaaggtgaa gaattaccat ttgacgtata
    10141 tggtcaagga atatattatg taggacctac tcctacaaag ccaggagaag ttataggtgc
    10201 tgcaggtcca acgacgagtt atagaatgga tgatttgact atacctcttt tagaaagagg
    10261 tcttagattg atgataggca agggaaaaag aagtgatgaa gttatagaag gtatgcaaaa
    10321 atacggagca gtttatcttg ctgcaatagg aggagctgga gcgtatattt caaattcaat
    10381 aaaatcatgt gaaattattg catatgaaga tttaggagct gaagctataa gaaagattgt
    10441 agtagaagac cttaagctta cagtagcaat agatagctat gggaataata tatatgagca
    10501 aggtcgagca atttatgaat gtaaataatg tttagaaata aatatgaata tcaaaattaa
    10561 aaatagttgt gtatatttta aggaggaaaa ttgatgtcta aggattatgc aaaattggca
    10621 ttagaaatgc atgaaatcaa caaagggaaa gtaagtgtag aaagcaaggt agaagttaaa
    10681 actaaggatg atttatcaac agcatataca ccaggggttg cagaaccttg tttaaaaata
    10741 catgaaaatc aagatgatgt ttatagatac acttctaaag ggaatctagt agcagtagtt
    10801 agtgatggaa gtgctgtact tggattaggt aacattggtg ctgaagcatc tatacctgtt
    10861 atggaaggta aagctatatt gtttaaacaa tttgcagatg tagacgcttt tccaatatgt
    10921 ttaaagacta atgatgtaga tgagatagtt aaatctgtag agttgatgga acctgtattt
    10981 ggaggtataa atttggaaga catatcttct ccaagatgtt ttgagataga agagagatta
    11041 aaaaaatctt taagtatacc tgtttttcat gatgaccaac atgggacagc aataatagtt
    11101 gcagcagcca taataaactc aataaagtta attgaaaata aaaaaataga agatttagaa
    11161 atagttataa acggagcagg agctgctggt atagccatag caaagatact acttaatatg
    11221 aatgttaaaa atataatctt atgtgataga agtggagcat tggaagctag tatagaaaat
    11281 ctaaactatg ttcaaaaaga aatgttaaaa gtaacaaata taagaaatga aaaaggacct
    11341 ttaaaagata ttataaaagg aaaagatgta tttattggtg tttcaggtcc aggagctgtt
    11401 acaaaggaaa tggttgaaag tatgtctgag aagccaataa tattggcaat ggcaaatcct
    11461 gctccagaga taatgccaga agaagcaaaa ttaggtggag catttataat gggaacaggt
    11521 cgttcagact tccctaatca agtcaataat gtattggctt ttcctggaat atttagagga
    11581 gcattagatg ttaaggctaa agagataaat gaagaaatga agatagctgc tgcatatgca
    11641 attgctaata caataagtga tgaggaaata tgcccagagt atatattacc agatgtattt
    11701 aataagaatg tagtaaaaaa tgttgctaag gcagttaaag aagcagctat aaaaactaaa
    11761 gtaaatagaa tataaatttt tatatgctca tatattctta cttttatata catatcttta
    11821 tgattaaacg tgttagaaaa cgtagtaaat ttatactatc agactttacc tttattactt
    11881 aaaatgatat aatatgaata ttataaatta ataaatttaa atttattgag gtgcaagaga
    11941 taatggaata taaagttaat gaccaagaac ttaatgcttc aatgtttatc ccattcgtta
    12001 acaggatatg gccaggagat tatgatacgg ataaaacaca gactgcatta tcaaaaactt
    12061 tgaatataac tgcttatgat gataaagtgc ttgtaggatg tctgcgagtt ctttcagatg
    12121 gttattattt tggaacaatt acagaattgc ttgttcttcc agagtatcag aaacaaggca
    12181 ttggtagtaa gcttttccag cttgctaaag agaatacacc aactatgcta tattttggtg
    12241 cacagccagg agtagaagag ttctatgaaa aaaatggatg ccaaagaagt cttcaatctt
    12301 acataataaa aaagaaagat agttattaaa gttccagctt tcaataatct taaaagtaca
    12361 atattttagt ggaatcattt cattttttat tactaatatg acataaacat gtcatattag
    12421 tattgatata cttttaatat ggttaagagc caaagaaaaa tataaggagt gatttaaaat
    12481 ggaagaaact aaattttgcc aatgctgtgc aatgccaatg ggacaaactg atgaattata
    12541 tgggacaaat aaagatggaa gtaaaagtac tgattattgt agttattgtt ttaaagatgg
    12601 tgagtttaca gctgatataa gtatggaaga gatgatagaa gtttgtatcc ctcatatgct
    12661 tcaaagtaat aaggatatga ctgaagatga agcaagaaca atgatgaaca atttctttcc
    12721 aacattaaaa cgctggaaat aattttatgc aaaattagtt atatgcaaaa catgaaatat
    12781 ggtgttgaga ataaggggtg gtgtgcttta tagcatacca cctgttttgt tacttgctag
    12841 ttcaggtatt cttgtatgct taaatatgtt ctcatctctc tttctatttt aaattgtaaa
    12901 aatctaaaat atgttattta tattctactt ctttatccat gtctttttct accacaagtc
    12961 aaatccaact acaaaatcat cattttcaat tcactgttta atagaattaa cagataaaga
    13021 gttataaaat tttctatttt ttatataaaa taatacaggt caagctgact tctagctact
    13081 tgggatagtg tatatattta tgatagttat aggagtaata ccaatcatta gactgttgat
    13141 ttgtgtagtc ttttgtaaaa acatttgttt taatatattg agtttttgaa aaagtaaaat
    13201 tataattata ataaattaag tgtaataatg tattagaagt aaaaataatt aaaatagagg
    13261 tgattaaatg agtagtatat tgttagttga agatgattta agcttgatat atggattaga
    13321 gttctctata caaaaaagtg gatttagtat agacatagca aggacagtaa aagaagctat
    13381 gcaaatgtat gaggaaaaaa attatgactt attgctttta gatgtatccc tacctgatgg
    13441 taatggattt cagatttgcg aaaaagtacg agaggtttct aatataccca ttatattttt
    13501 gactgcttca gatgaagagg taaatgtagt gatgggtctt gatatgggtg gagacgatta
    13561 tataacaaaa ccttttaaat taaatgaatt aatttcaaga ataaaagcat tacttagacg
    13621 ttataatgtt gcaagtaatg tgaatgaatt aagttcaaat aatattacta ttaaattact
    13681 tgaaaatcgt gtttttaaag gtaaatttga ggtggaactt accacagcag aatataaatt
    13741 attgtgctta tttatgaaaa ataaaaatat tgtacttact agaaaaaaca tattggacaa
    13801 gttatgggat ggaaatggta gctttataga tgacaataca ttatcagtat atgtaagacg
    13861 attgagaaat aaaattgaag ataatcctga aaatcctaag tttctattga ccgttagaag
    13921 aatgggttat aagtggaatg taattaagtg agggtattaa tatgaagata ttttctaata
    13981 aagatataaa aatatttttt ttaatgctta tatctatttt agtaatgttt attatagtag
    14041 ggcaaatagt ggttataagt ataactaaca attataaaaa aacgttgata gagcatgatt
    14101 ataatatagc tggatactta tatagtatag gtgttgataa atctaaaata ccatcagcat
    14161 ttgttgcaca tgaagataaa tatattttaa aaggaaaaga aatactagat acagctggat
    14221 atggatttga tatagatgtt agctttacac caagtgtaaa attgtttcaa agtaaatata
    14281 taaaaactat gtctatctat ttattagtat tttttactat gattattttt atactatata
    14341 tgtatttttt taggcaacaa agtaagatag aagaggctag ttataaaatt gatttattta
    14401 tgaatggaaa tataaatgaa agactaaata catatgaaga aggtagctta tcaaaattat
    14461 ttagttcaat agatgttatg tcgacatctt taaatacaca tatattaaaa gaaaaacaga
    14521 gcagagaatt tcttaaaaat acaatttcgg atatatcgca tcaattaaaa actccactta
    14581 cagctttaat aatgtacaat cagatactac aagaagaaag tcataatagt gatgtcgttg
    14641 aagcttttgt acaaaaaagt caaagtgaac tagaacgcat tgaaacattg attaagaatt
    14701 tattaaagat tacaaagata gattcaaaaa caataattct caataaaaat aacgttaatc
    14761 ttaaaaattt aattgtcaaa attttgtata gctttgaaac tagggcagaa aaagaaggaa
    14821 aggttatttc tgtaaatggt tcagaaaata cattgttgtt ctgcgattat gaatggatgt
    14881 cagaggcttt aagtaatctt ataaagaatg cattagataa tacaaaagag aatgataaaa
    14941 taacgataga gtggtttgag acgactataa ccaccattgt ttcagttaaa gatactggaa
    15001 atggaatcca tgttgaggat attcatcata tatttaaaag gttttataga agtaagtttt
    15061 caaaagataa tcaaggttta ggactgggat taccactagt taaatctatt gtggaacaac
    15121 ataatggtac tatttctgta gaaagtaaac tatcacaagg aagtatattc accataagtt
    15181 ttttaaagct tactaatatg taagataaaa tacatcttgc agtaaggtat atagattatt
    15241 attatattaa tcaattagaa aggtgagaga gaaaatggat attcttgtgg ttaataattt
    15301 atgtaaaaca tatggaaatg gatatacaaa ggtagaggca ttgaaagatg tatcctttac
    15361 agtttcaaaa ggagagtttg tgactgtagt tggagaatct ggttcaggaa agagtacact
    15421 attaaatctc ttaggaggtc ttgatactcc aacatcaggg agaatattta ttgatggtaa
    15481 agaaatatgt tcaatgaaag aggaaaaaca gactattttt agacgtcgta acatagggtt
    15541 tatatttcag gcatataacc ttataccaga actaactgtg gagcaaaata taatattccc
    15601 attgttatta gattataaaa aaccagatac tatttactta gatgaagtat tgactatttt
    15661 aggtcttaaa gataggaaaa atcatcttcc aaatcaatta tctggtggtc aacaacagag
    15721 agttgcaatt ggaagggctt tgattacaaa gccaagtatt atactggcag atgagccaac
    15781 gggaaatctt gacagtaaaa atagtaatga tgtaatttca cttttaaaag tgactgcaga
    15841 aaagtataat caaaccatta ttatgataac tcataatacg aatatagctt ctacagcaga
    15901 tagaatacta caggtttctg atggtgtgct tacagacctg ggggtgaata gagaatgaga
    15961 agctacttag aattagtacc acaatatgca aaagtacata agaaaaaaaa tagaactaca
    16021 attttatgta ttattattgc agtatgctta gttactgcta tctttggact tgcagatatg
    16081 gctatacaat gtcaaaagat acaatttatt aaagatgatg gaaattggca catagtaatt
    16141 agaaatattg atgaaaagtt tatatcagaa ataaatagta gagtagatat agctcaccat
    16201 ggtagggggc aagtcgttga caatggagag tttaaatcaa aggagatttt gatacaaggt
    16261 ttagatgaag aagtagcaaa gcaatttaac ttagaaataa taaggggtcg ttatcctatt
    16321 ggggagaatg agactttaat agatgaggat gcagttaaaa gctttaatct aaaaatagga
    16381 gattttatca aaataaaatt agcagatggt agaaataaaa attataagat agtaggtgaa
    16441 tattcatcaa tatcaagctt aagagctaca gataaacatg gattaatact ttcaatattg
    16501 ggtacacaag ctattaaaaa atcagaaacg tacgattatt attatattac atttaaagaa
    16561 aaggttaata ttagaaaagc cacttctgat attaaaaata ccttcaattt aagtgataaa
    16621 caaattggta aaaatgaaag attactttct attataggtc aaggtgactc tgacttttct
    16681 aaaccattgt atttaacagc aggattactt tttgtacttg ttttagtagc aagtattatc
    16741 atgatatata atagttttaa catgagtgta attgagagag ttaaattttt tggtctgtta
    16801 cgttgtctag ggtcatcaaa acatcaagtt aaaaaatttg ttgttttaga aagtttaatt
    16861 ttaagtataa aagctattcc aataggctta gtattaggaa gtcttgtaac tattatatct
    16921 tctatatttc ttaagtatgt taatgagtta ttcagctcaa tgccaatttt aaaagttagt
    16981 tttattggta ttgcatttgg aataattgta gggtttttaa ctgtaatatt atcagctatt
    17041 attccagcaa aaaaagcttc ccgtgtatct ccacttagcg ctgtacgtgg gaatctaatg
    17101 tccaaagaaa ttttaaataa cgggaagaca agtaaagttg caaatatagg aagttttaaa
    17161 attgagactt ctatgggatt aaatcatgct ttttcaagaa agaaatcttt tgtacttatg
    17221 acttcttcat ttgccattag tattatacta tttttaggtt ttagtgtgct tatagacctt
    17281 atgtatcaag gacttaagcc tatgaagcca gaagctcctc atatatctat tgttgaccct
    17341 aattttaagt ctgttttaac taaggaagat attaatgaaa taagcaatat caaaggagta
    17401 aagaaagtat acagtagaat gatgacggat atagaagcta catataatgg gaagaagaca
    17461 aaatcacaat taatttctta tgaaaagtat caatttaatt gggcaaaaaa atatctatta
    17521 aaaggagaag ttaatgaaaa taaactacag tcagaaaacc ttgcattagt agaagagggg
    17581 catggatttg atataggaga taagatatat attaaaaatg gaaatgctga aaaagagtta
    17641 gaggtaggag gtatactttc ctcaattcca tttgaggcta aagataaata tattggaaat
    17701 attataacat ctgaaaatac ttttacgaat ataacaggta taaagggtta tataataatg
    17761 gatattcagg ttgataaaga tactcctgga gatttaattg aaaatataag acgtgtagta
    17821 gatgataact tagaggtcag agataaaaga caaagtaact tagaggttaa aaattcgttt
    17881 tatactatgg caacatttgt atatggattt gtgtttatta ttgcgattat aagcatgttt
    17941 aatatcataa atagcatgaa tataagtgtt acaagtagaa agaattacta tggtgttatg
    18001 cgtgcagttg gcatatccaa cagacaatta agaagaatgg taatagtaga ggcaggttca
    18061 tatgcagtga gtggttgttt attaggtagt atactaggat taatattaca taggtatatg
    18121 tttatatcgt tagtaagctc aatgtttcat ttagagtggc aagtaccttt taatttacta
    18181 cttatcactg tactaactat gataataata actttattat cagtaagaaa accaatcaaa
    18241 aagatttgtg aattagatat aatagactca ataaatgcac aataaatata ggtattgatt
    18301 taaattaaaa aaacgaagta aaaatgaaat agaaaatatt tttcattttt acttcgtttt
    18361 ttatattata aaatttttgt tatgttacaa aatttctata aagatgatgt gaatctaaac
    18421 attatatgac aacgtgagca tttaagttaa aatattttaa atatactatt ttagataagt
    18481 tccctcttca tcttgataaa ttaatccttt tttcataagc actccaagag ctcgtttaaa
    18541 atttttctta cttgaattaa ataatataga aatatcttta gggtcagatt tatcattaaa
    18601 tctcatatat ccatcagaac cttctaaata acttaaaatc ttattttcta aagtatcaag
    18661 ttcatccttt ctatttcctc taggagaaag accaagtttt ccatcttcat atatttttat
    18721 gacatgtaaa ttttcaagaa catcaccagt ttttagttca gtaaagtact cattatgaag
    18781 tattacacca gcatatttat tgtctacaca tatcattgca gaattattag tttggaatcc
    18841 atatacaact ccagttacaa tatctcctac attgtaagta tggtctgtta ataagtatga
    18901 atctatatct gtagtagcag caattctttt gcttttgtct aaatatatat aaaataaata
    18961 tttttcgtct ctaaatagtg gataagtctt agctttaaaa ggaactaata tgtctttagg
    19021 aagtcccata tctataaaag taccaatgtc tgtattatca actactttta aatgtgctac
    19081 atccccaacc ttagctaaag gcggtattaa agttgcagca gttctgtcat cagaatcttt
    19141 aaatatgaaa gcatttactt catcacctat gtttatttca ttttttccga ttaatctatt
    19201 atgaagaagt atatcgtctt ttgtgttatt agtttgtcca tccaaaaaat atccaaattc
    19261 agtttttctt tttactgtaa gtttattaaa atcacctatg tttatcaaat taaaatcatc
    19321 ctctcatttt atatttataa tttagccata atatacttat gtagtagttt gtcacagtat
    19381 ctatattagt attagtgaaa tttacaataa ataatatagt tatttatgta tttttcaatt
    19441 ctctagcttc ttatatagta taaactccaa tttctttttt gtctttaggt tttattaaaa
    19501 tttttacaaa ataagttaaa aagtattgaa ataaaatttc ttttaaagta taattggtat
    19561 ataccaaaat tggtatatac catatcgaaa agtggtgact atatgaaaat agtaaataaa
    19621 tctagtaata taccattgca tactcaatta agttcaataa taagagagat gatagaaact
    19681 ggtgagctta aagagggcga tgcaataatg ccagaaagag aactttgcaa catacaaaat
    19741 gtaagtcgta tgacagtaaa taaaaccatt gttggattag ttacagaagg acttctttat
    19801 agggtacaag gtaaagggac attcgttgca aagcaaaaaa agaagtatca gttttcaaat
    19861 gtaaaaggtt ttactgatgt tatgaaagaa aagggagtaa acataaaaac ggatatatta
    19921 tcctttgaga tggaactacc agatgattta gttaaaagaa agcttggaat aagtgataat
    19981 actacaaata tatataagat tgtcagactt agatatactg atggagagcc atttggatta
    20041 gaaatagtat atctatcaga agaaatgtgt aagggtctaa caaaagggat attggataat
    20101 tcttcattat atagggtttt aaatgaaaaa tatggctata agatacaaaa agctgaacag
    20161 gtaatggagc cagtaatact ttcagatgaa gaaagtaagc ttcttgaaac agatgaaggt
    20221 gctttagctc ttaaacttca tagaaattcc tataatagag aaggtagacc tatagaatat
    20281 accatatcaa tatttagaac agataaatat caatatgaaa tagtattgag tgagtaggtg
    20341 aataatatga aatgtttaat taatggaaag ataatattaa aaaatcaaat cttagaaaat
    20401 aaagtattag tatttgatga aaaaataatt gatatagctg atagtgtacc aaaagattgt
    20461 gaagttatag atgctgatgg aaaatatata tctccagggc ttattgatat tcatatacat
    20521 ggaaacatgg gaaaagatac aatggattcg actgatgaat ctattgaaac aatttcaaaa
    20581 tcaattatga gacatggagt aacatctttt cttccaacta caatgactat ggataaagaa
    20641 catgtttatg atgcacttga agttattaaa aaagcccaaa atagaaagct tgaaggggca
    20701 caagtattag gagcacattt agaaggacct tttataaatg agaattataa gggagcacaa
    20761 aatgaaaaat ttataataaa ttcaaaatac gaatttataa aagaatataa agatgttata
    20821 aaagttataa cttatgctcc agaaaaagat attgattttg attttactag agaaataaaa
    20881 agatgtacag atatagtttt atctattggt catagtaatg caaattatga ccaagctaaa
    20941 gaagctataa atttaggagt aactaatgta actcacatgt tcaatgcaat gactggttta
    21001 aaccatagag acccaggcgt tgttggtgca gcacttacaa ctaatgtgta cagtgagtta
    21061 atagcagata caatccatat aaataaagat ttatttcaat ttatactaaa taataaagga
    21121 aaagaaagac tgattttaat aacagattct atagaagctg gtggtcttga agatggcaat
    21181 tattctcttg gaggtcagaa agtcatagtt aagggtaatg aagctagact tgaaaatgga
    21241 gcattagctg gaagtgtgtt gtctttaaat aaaatggtat ttaacttctt aaataataca
    21301 aaccttaaag tgaatgaagc aattaattta gcttctttaa atccagcaac atctttggga
    21361 ataaatgaca aaaaaggaag cttagaaata ggtaaggatg cagatatagc tgtatttgat
    21421 gagaatttag attgtaaaat gacactttgc ttgggggaag tagtatataa aaatatatag
    21481 tatacaaaac aaaccttaaa gacagtaaaa acaatataaa aaataataaa ttaaacttac
    21541 attagtaaaa gtagtagtta aaatttagga ggaataagat gagagtatta gtgtgtaaag
    21601 attatgatgg aatgagtaaa aaagccgctg aaatgatagc agctcaaata gttttaaaac
    21661 caaattcaat actgggacta gctacaggaa gtacaccagt aggtatgtat agagatttag
    21721 taaaaaaata caatgataat atagtagatt tttcagatgt gatgagcttt aatttagatg
    21781 aatattataa gttaccaata tctaatgacc aaagctatga ttattttatg aaagagaatc
    21841 tatttaatca tgtaaacata aagccagaaa atactcatct accaaatgga atggctgatg
    21901 atattgaaaa agagtgtatg aactatgaag cttctataga tgcagctggt ggtatagatg
    21961 tacaagtact tggaataggt cgtaatgctc atataggttt taatgaacct gatactaaat
    22021 ttgcaaaaag aactcatgta gttgaactta cagaatctac aatagaagct aatgcaagat
    22081 tctttaaatc aagagaagat gttcctaaaa aagctgtaag tatgggaata ggttcaatat
    22141 tgaagtctaa gaaaatattg cttttagctt caggagaaga aaaagctgat gcagtatata
    22201 atactgttta cggagatata actccagaag ttcctggttc tatacttcaa cttcataaag
    22261 acactatagt tatagtagat gaagcagcag caagtaaatt gaatccaaaa gattataaat
    22321 tagttattat tgtttaaatt acttgcttat tactttttac gaaaactcgt tatcaagaag
    22381 tatccaaata agatgttaaa aattattatg tttagtggga ttctatcaag cataataaaa
    22441 ttacctataa ttgggatatt accaactgga aacataaaga agaatacagg catcagtgat
    22501 agtaaaaaag atggaaaaca aagaagaagt aatcttggaa tatcaatata ccaactacca
    22561 tcctttttgt attctctaat caataattca gttcctagta ataaaccaat accaccagag
    22621 gaaattaaat taataaaaat gtatctttta aagtcttgca tataaccagt gtaaaattga
    22681 gtatagaaat cataatttaa tttaacggct aaaaaataca taagcaatag aatgattaaa
    22741 aataaaagat atctaagagc ttttttcatt ttaaattctc ccttcagaaa tactttattt
    22801 agttttattt tgttggaatc tgattttatc atttagttta agaaatccat aatattagtg
    22861 aagaatgaaa taagtattat atatgaataa atatttttag aattaaggtg aattgtagtg
    22921 cttaatataa ctataatatt aattgtttga atattcaata aaaagttcga aaaatatcaa
    22981 ttctgatata aactgaataa atacagttga atattaaatt attattttat caaaaatatg
    23041 caaagtacta caccttcaaa tatcacctaa agtaattaaa aggcaattaa agtgaagtag
    23101 ttcaagtatt tctaaaataa gtttaataaa ttctataata atttattttt tgccttaaaa
    23161 ttgccttaaa atccaaacaa ttttaaaact aatgtactat aaaaagctgg tataatttaa
    23221 atatagtaaa aaataagatt tatcttatct attgggattt aattatttaa tcaatatatt
    23281 tataccattt aatttaaata aaaagtctat taaggagtga gcttatgagt aagttaattt
    23341 atatagcaga tgatgaagat aatataagaa atttggtaaa gacattctta aaaaatgaag
    23401 gtcatgatgt tatggatttt aaaacgggtg atgaactttt agaacaattt aatataaagg
    23461 agtgtgactt agtaatacta gatataatga tgcctggctc aagtggtttt gaagtatgta
    23521 caaaacttcg tgagaaaagt acagtcccaa taatcatgct tactgcaaga gatacagata
    23581 tagattatat tacagggata accttaggta gtgatgatta ttttacaaaa ccatttagcc
    23641 caatgtcttt ggttatgaga gtaaaatcta tatttagaag gatagagttt gaaaagaaac
    23701 aaaattatga taaatatagt aactcgatag atatggaatt aaaatttggt gatgtaataa
    23761 taaataaaaa gaataaaatc gttacaagta aaaatgtaaa tatagacctt acaccaaatg
    23821 aatataacct attgacttat ttgtttgaaa atatagatag agcaatttcc agagatgaat
    23881 tattaaacaa aatatgggga tacgatatag aagttgagac aagggctgct gatgatacag
    23941 tgaagagatt acgtaaaaaa attttagata caaatatttt aatagaaact gtatgggggt
    24001 ttggatttag gttgaaggag aaaagttaag atgaagaatg gaaatgacaa gaatagaatt
    24061 ggaaagatta aatccaaatt taaattaaag ttctcaaaga aaaatataag cataaaaact
    24121 aggattttgt tgagtatact ttgtttgata attatagtat ttatgataat attagtatct
    24181 tttaatgtat ttcttgatac atatataaaa acaactgcga atgaagaatt gacaaagtct
    24241 acagaaatag tagaacatat ggatagtaat tttagaccta ttaagccacc acaagatgat
    24301 ggaaagcttc ctcccaaagt attatctaat tttatgagaa atgtacaaga taaagttagg
    24361 atggcagaaa cacaatcaga tgctgatgct atggtagttg attctaagta taacctgata
    24421 tttccaacaa gagaggacga tttcttaaaa aatgttgatg agatggagct gattagggag
    24481 tgtattcaaa atgaaaaatt agatttaaat tcagatgcaa atacacggat atctaccaga
    24541 aataaggatt attatatttc aactgtaaaa attaccagta tatatggtga acaagacaag
    24601 tatcttatac tttttataga catatcaaaa actctaaatc tagcacaaaa gataaatatt
    24661 gtattaatat ctgtaatgtg ttttgctgga atattagcaa tatttacagc tgtgatttta
    24721 tctgagaaaa ttgctaaacc gataaaagag ttgtgtgagt ttgcaaaaaa aatgggtcaa
    24781 ggagatttca aaagaaccta ctttgacttt tcagataaag aattagtaga gctctcaact
    24841 gttatgaata agagtgctga gtatctggat aagtatgata atgaacaaaa aatatttttt
    24901 caaaatgcat ctcatgaatt aaggacacca cttatgtcta ttaaaggtta tgcagaagct
    24961 ataaaatata atgttataga tagtaaacat gcaagtgata taattcttga agaaagtgat
    25021 aggttaagtg atatggttga agatttatta tacatttcta aaatagataa tataactaaa
    25081 gattttgaac ttgtagaatg tgatttaaga gaagtacttt caaactgtgg agctaggcaa
    25141 aatgtaagag ctataaataa ggggataaag tttatttatg aatttgatga agaaatggtt
    25201 ttatttgaat gtgatgaaaa aaacatttcc aaagcattta tgaatcttat agaaaatgct
    25261 ttgagatacg ctaagagtga aataaaaata gtgtgtaagt ataatcaaaa aaatatagtt
    25321 gtgataatag aagatgatgg aattggaatc aagaaagaag atttacctca tgtttttgaa
    25381 agattctata agggagtagg aggaaatcat ggaattggat tatcaatagt taaatctatt
    25441 gtaaataagc atggtgggcg tatatacgta gaaaatggca aaaaaggagc taaatttact
    25501 atattattta aattgtaaaa aaattagaga aaatatagag atgtttgaag ttgtttttta
    25561 tatatatctg ttgtatactg ttgaaaaaag aacaatatta agctgacata tattacgata
    25621 gttgacattt aaagtaaatg cttaaatata gatacgaaag gaaaagtaaa atctgaagtg
    25681 tatttaggtt taagtaagct tcttatttta taaaaaatat gtatgaaaga acagctgatt
    25741 tttaatatta caaatttagt aacggttgta tttgaagctt ttgtcatcca tatgttttta
    25801 tcagactttt taggccagaa agaagggtat ataaaagttg taagatatgc taaactgggt
    25861 tttataatat gtttaggatt ctgtaattta ataactttaa accctaaaat cacaatgcct
    25921 ttaattttca tccttatttt ttcaacatca tttttatata aaggaaattt aaagacacga
    25981 ttgtttacta ctgttttatt aagtatattc tttatactgt cagaaattgt agttacaagt
    26041 atttttgttt tatttgtaaa agaaggcttt gaaataatgc ttgaaaataa tagtataaga
    26101 gtattggcga caattttatc taaaattgtc tttttgttga cttgtaaaat tatttgtcta
    26161 tttaaaaaag atgtacattt agatatgccc ataaagtatt ggctcccttt atttttaata
    26221 cctatattta gtttatttct gtctgtttct atctttgatg taagtaaatt ttttagtctt
    26281 gaaagtttaa aatttctaag cttaatatct agtgttggta ttttatatat taattttatt
    26341 gtcttttatt tatttaaatt tattatagat aaaactaaac tatctatgaa atatgaacta
    26401 cttgaaaaag aaataattca taaggaagaa ttaagactta gtaatgagtg ttataaaatt
    26461 attgttgaac agactgattc tgtcgttttc gaatggaata tcaaagaaaa taaatcattt
    26521 gtatcgcagg cttggactga aaaatttgga tataacaatg catgtaagaa tatttttaaa
    26581 gaaattaaag ataaagactt agttcattct gaagataaag ctatatttga aggttttctt
    26641 gaaagtatta aaaaaaagaa tatgcacaat caagcagtat atcgtttaaa aaaatctaat
    26701 ggtgaatata tttggtgtag aacatcaatt acaagcattt ataatgatga aaatgaactt
    26761 ttaagagttg tcggagtaat tgtagatgta gatagtgata taaaaaaata tgaagagtta
    26821 agaactagag cagaaagtga ctcattgacc aatatataca ataaaggtac atttgaaaaa
    26881 ttagtggaag aaactatagt tatgaataca ggtgataaaa aagatgcatt attcattatt
    26941 gatttggatg attttaaaga aataaatgat aattttggtc atccatttgg tgattttgta
    27001 ctaaaaacat ttgctgataa gatacaaact agttttggta gtaaagactt agtcggaaga
    27061 attggtggag atgaatttgt tgtatatatg caagattatg ttacagaagt aaatttgcat
    27121 aaaaaagcta aagaattaaa tagagtactt tcggataatt acactgattt gagttttagt
    27181 tttgatgctt ctgtcagtat aggtattgca aggtatcctc aagatggaac ttcatttttt
    27241 gaattgttta aaaatgcaga tagagcactt tatagcataa aagcatcagg taaaaattca
    27301 tattgtttat ttgaagaaga actatatgta cagtgaattt gaatttagat tttatgtgag
    27361 agtaagattt atatatactt gtggctgtct gatttataaa atatgttact ttgtatattt
    27421 ttatatgttt cagtaaggtt aattaacata agcaaaggtg taagtaaatt tatattagtt
    27481 taagtttact tacaccttta taaaaataca aataatagat tcatttacat tcttaaatga
    27541 ttaaagctct ttaccttcta aacatgcata acatatcgtt ataattccag taaataagac
    27601 taaaataccc attcctaaga ttacagtttc attatctatt actccaaatg tttttaaagt
    27661 aacttatttc gctttgtatc ataataattt gtctcttttt acattttaac ttctgctgag
    27721 atttgagtta gatattcgtt agaatctcgc acacttatat catatagaag atattcttca
    27781 taaacaaaat ccccaatacg taaattattc tgattaaaaa aatttaataa cttttcataa
    27841 gccttgtaaa tagtttcata actcccttta tgataagcag ttacataaag tccctttggt
    27901 ttgattgata caggatattt cttgtactct ttattaactt ttgtaaataa atatgaatat
    27961 gattcaaagt ctttattaat tatatcttca cctttaatga ttgagccaat cgtaccataa
    28021 tcactcaatt catagttgtc cataaagtta atacattcat ataaaaaatt ttcttcctca
    28081 tctcctaaaa actgttcttt atatgtaaca ggtgttttga ccaagtactc ttcttcatgt
    28141 tcttttaaag taatagtatt cgcatctata ttacaggcat ttttagtgaa tgaaatagta
    28201 gattccatta gagcttgaat attatttagt ttttcaattt catttttaat atcaatggtt
    28261 ttcttttcta aaagctcaat tagtaaatta ggtgttcttt tgtctatata agctttaatt
    28321 tcttttaaag gcatttttac ttccctaagt gaagaaatta taccaaaaat gctaagttga
    28381 tggtatgagt agtatctata tccattttct ttctttaatt ctggtgagaa aagacctata
    28441 tcatcataat ggaaaagtgt ttttttattg attccacaaa tctttgcaaa ttctccagtt
    28501 gtaaaataat tttttgaaac ttgactcata attataattc ctccttgact atcctgttac
    28561 agtatagttt atcatagtat tttgtaaagg agtgtgatta tatgaaaaaa ttaattcatt
    28621 ttttaaaacc atatagagtt ttaattgttg tagttttgat atttacgttt ttacaaacac
    28681 ttggaacttt gtatatacca acacttacag caaatatagt aaacaatggt gtagtaaagg
    28741 gagatataga ttatattgta aaaacaggtt taatgatgat gatagtagct ggtataacag
    28801 ctttatcagc tgtgttagtt tgtaaagtat cagcaaatct ttcatctgga ttttgtagag
    28861 atattagaga agcagtattt ataaaatcac aagatttatc aataaatgat tttaataata
    28921 taggtacagc atcaatgatt actaggagta ctagtgatat tactttaata ggtcagtctg
    28981 tgtttatgtt tattcaatta gtattaccag caccaattat aactgtttct ggtctattct
    29041 tagcatattc tatagataaa gcaatgacaa ttattattgt tgtagtaatg tttttattca
    29101 tgctttcagc atttttagtt ggtaaaaagc ttataaagtt gtttaaaatg atgcaaataa
    29161 aaatggacaa tatgaatagg gtgttacgtg aggtagtaac tggagtaaga gttataagag
    29221 cttttaatag gagtcatttt gaaaaaaaga gatttgatag aactgcaata gattattctg
    29281 aaacagcaat ttcaataaat aaaatatttg cagtacttat gcctattgta atgttaataa
    29341 tgaatttagg tatagtaagt attatttggt ttggtgggat gagagtcagt aatggaaata
    29401 tggaaatagg tcatataatg gcacttgttg aatattgtat cttaatttta ttctatttaa
    29461 tcatgggagt aatggtattt atgtacatac ctagagcagg tgcatgtgca gatagagtaa
    29521 atcagatatt agatatagaa cctgaaattg tagatggaaa tggtcataaa gatactgtct
    29581 cagagagagg acatttagta tttaaaaatg taaccttttc atatgcacaa tcagaagaac
    29641 ctgtgttaaa taatataaca tttgaagcaa aatctggaga agtaactgca attataggaa
    29701 gcactggctc aggcaaatct actattgcaa atataatacc acgttttttt gaaattcaat
    29761 ctggagaaat atctataaat ggtcaggata ttaagaagat tcctcaaaaa gaacttagag
    29821 ataagattgg atttgtacca caaaaagctt ttttatttag tggaacaata gaagaaaata
    29881 taaggtatgg aaaagaagat gcaagtattg aagaagtaaa gcatgctgca agtatagctc
    29941 aagctgatga atttatttct gatatggaag acaagtatga ctcatttgta gcacaaggtg
    30001 gaaataattt gtcaggtggt caaaaacaga gaatatccat tgcaagagcg ttagttagaa
    30061 agcctgaagt atatgtcttt gatgatagtt tttctgcatt agattttaaa acagataaaa
    30121 gacttagaaa agcgttgaaa aatgaaatca aagattcatc agctataatt atagcacaac
    30181 gtataagtac aatcatggat gctaatcaga ttatagtttt aaatgatgga aaaattgtag
    30241 gtattggaaa acataaagat ttacttgaaa attgtgaagt ttataagcaa attgcggatt
    30301 cacaacttag taaagaagaa cttgcataaa atgaagaatt aatctgatat ttggaggtgt
    30361 atgatatgag tgaaaaaaga atagatgaac aagatataga agtacttagt tttgaagatg
    30421 gcatgtcagc agaaaaagct aaggatgcaa aaaaaactac taagagatta ttaaaatata
    30481 tggcaaaaca aaagtttaaa atattaatta tttttatttc agtattgata agttcagcgc
    30541 ttacagtttt agcacctatg gttatgggaa aagctattga ccaactattt aatggaataa
    30601 aaactgcagt ccaaacaggt acaaaattca gtgtgaattt tagtactatg ggggggatag
    30661 tatcaatact tctagggttg tacttaatta gtgcagtatt tatatatatt caacagtata
    30721 ttatgtcagg agttgcacaa aatctagttc ttagcatgag aaaagattta agtgataaac
    30781 tcaataaact tcctcttaag tactatgatt ctcataaaaa gggggaaaca cttagtatag
    30841 taacaaatga tttagaaaaa gtagcagata gtttacaaga aggattaatg caacttatta
    30901 cagcagtagt tacagtagtt ggttctattg taatgatgat aagtataagt gtaccactta
    30961 caatagtatc agctataaca ttacttgttt cattgggtat tactgttgta attgcaagaa
    31021 aatcacaaga aagattctct gaaaatcaaa aggcactagg agagttaaat agcaatatag
    31081 aagagatatt tactggtcaa atagtggtta aagcatttag taaagaaaag gatactataa
    31141 gaaactttaa aatattaaat caaaatcttt ataatgcaag tagaaaagca cagttttcgt
    31201 catatgcaat atctccaatt attagattta taaacctaat tggctatgtt attatagcag
    31261 ttgtaggtgg gatatttgca tcaactggag caatgactct tggtagtata caagcgttta
    31321 ttcaatatgt aaatcaagca tcagagccta ctacagaaat atcttatatt gtaaatatgc
    31381 ttcaagcagc aatagcatct gcagagagag tttttacagt tatggacgag gtggaagaga
    31441 taaaggatga agaatcttca aaggttatta gcatgcctaa aggtaaagta caatttgagc
    31501 atgttaaatt tggatatagt gatgatttta ttcttatgaa agatattaat atcaatctaa
    31561 atgcaggaga taagattgca attgttggac ctacaggagc tggaaagaca actcttgtaa
    31621 atttacttat gagattttat gagatacaag gtggaagaat tactattgat ggtgttaata
    31681 taaaagattt aaagcgtgga gaacttagaa ctatgtttgg tatggttctt caagatacat
    31741 ggctgtttaa tggaagtata aaagaaaata ttgcatatag taagtcagat gccacaatgg
    31801 atgaaattgt aagagcagca aaatcagcaa gagtagacca ttttataagg actttaccac
    31861 aagggtatga cactatattg actgaggatg cttctaatct atctcaaggt caaaagcaac
    31921 ttctaacaat tgccagggca atactttcag acccatcagt attgattctt gatgaagcaa
    31981 catctagtgt agatactaga acagaggtag aaattcaaaa ggcaatgaat aacttgatga
    32041 agggaagaac tagttttgtt attgcacata gattatcaac tattcgagat gctgatttaa
    32101 tattagtaat gaaagaagga actattattg aacaaggaag ccataaggaa cttattgaaa
    32161 agaaaggatt ctatgaagaa ctttataaca gtcaatttac aagtgaatat gatgaagatg
    32221 ttgtatgatt atcaagtttt aggcaactaa atgattgata aatattaagt taaatatagt
    32281 aacatgtaag gttatatgga ataagagtat ttctctattt catataacct tttttattta
    32341 tcaaaataag ataaaatttc ctttctaaat tagattgaag aatgtattta tcaatataaa
    32401 agtaaaataa tcattattat tagtgaagta aatattgttt gccacatata tgccataaag
    32461 atgcacttat tttacggaga tttaacaaag tagtgtaaag tatactctaa atataaaata
    32521 aatcaaatag agttaaataa attgagaggt gatataaata gtgaataaaa aattgaacta
    32581 tagatttgaa atgaagcaca aaataactga agcagatgtg ttagctttaa aatcaagact
    32641 ctatcaaata atgaagaaag atgaaaatgc atctaaagat ggaaaatatc ttattaggag
    32701 tttatatttt gatactcctg aagataaagc acttttggat aaattaaatg gcgttgcaat
    32761 aagagaaaag tttaggataa gattttataa taatgactgc tcttatataa ggctagagaa
    32821 aaaaatcaaa cattacaaca tgacatcaaa gctatcaact aatttaacca aaaaagaagt
    32881 aataaatata ctaaataatg atattgaatt tctaaaagag tcgacaaatt gtttattaag
    32941 agaattttat ttgaaattaa aatgtgaaag attagaggca aaaagcatag ttgattacaa
    33001 tagagaagct tttatttatc cagttggaaa tgtaagagtt acaatcgata gtgatattaa
    33061 aacttctgta aattcggtag atttatttaa taaagatttg ccaactgttt cggtaattga
    33121 tgagaatatg actgtattgg aggttaaata tgatgaattt ataccagatt ttataaagga
    33181 tttaattcaa attaataaga ctacctctac agcagtttca aagtatgctt caagtagatt
    33241 atatatttaa gaataaaggc tatgatttat ataaagatat acataaataa ggttaaaaaa
    33301 caaataagtt aaaaataaat aaaataaaaa ataaataagt taaaaatagg aaggatgatt
    33361 ttaattatga catttaatga tatttttaaa tcaagtttta tagaaaacgt atcaggtttt
    33421 tcatttgtgg acagtgcttt agcactaggt tcagcttttt tagtaggttt gtttatatat
    33481 atggtctata aaaagactta tatgggaatt atgtattctc gaccattcaa tgtgtcgctt
    33541 gtagcactta caatgcttac aacttttgta atattggcag ttacttcaaa tgtagtttta
    33601 tccttaggta tggttggtgc tttatctata gtaagattta gaacagcaat taaagaccca
    33661 atggatttag tatttctatt ttggtcattg ggttcaggta tagttttagg agcaggtttg
    33721 attcccttag ctgtcatggg ttcaataatt atgggattga ttctaatatt cttttcaaat
    33781 aaaacaatat ctgaaactcc atatatattg atggtaaatt gtaataatga agattcagaa
    33841 gatatagcaa ctgataaaat taaaaaagta tttactaaat atcaaataaa atcaaaaagt
    33901 gttacaccag aaaaaggaat agaattagtg tttgaagtaa gaatgaaaga tggagaaaca
    33961 agtcttataa atgacttgag tcaagtagat ggagttacta atgcagttct tgtaagttat
    34021 aatggtgact atgtagcata gagaggagta atcttttatg aaagataaaa aatttaccct
    34081 tcttatctcg attatgatta tatttttatg tgctgtagtt ggagtttata gtacatctag
    34141 caacaaaagt gttgatttat atagtgatgt atatattgaa aaatatttta acagagacaa
    34201 ggttatggaa gttaatatag agatagatga aagtgacttg aaggatatga atgaaaatgc
    34261 tataaaagaa gaatttaagg ttgcaaaagt aactgtagat ggagatacat atggaaacgt
    34321 aggtataaga actaaaggaa attcaagtct tatatctgta gcaaatagtg atagtgatag
    34381 atacagctat aagattaatt ttgataagta taatactagt caaagtatgg aagggcttac
    34441 tcaattaaat cttaataact gttactctga cccatcttat atgagagagt ttttaacata
    34501 tagtatttgc gaggaaatgg gattagcgac tccagaattt gcatatgcta aagtctctat
    34561 aaatggcgaa tatcatggtt tgtatttggc agtagaagga ttaaaagagt cttatcttga
    34621 aaataatttt ggtaatgtaa ctggagactt atataagtca gatgaaggaa gctcgttgca
    34681 atataaagga gatgacccag aaagttactc aaacttaatc gttgaaagtg ataaaaagac
    34741 agctgattgg tctaaaatca caaaactatt aaaatctttg gatacaggtg aagatattga
    34801 aaaatatctt gatgtagatt ctgtccttaa aaatatagca ataaatacag ctttattaaa
    34861 ccttgatagc tatcaaggga gttttgccca taactattat ttatatgagc aagatggagt
    34921 attttctatg ttaccatggg attttaatat gtcatttggt ggatttagtg gttttggtgg
    34981 aggtagtcaa tctatagcaa ttgatgaacc tacgacaggt aatttagaag acagacctct
    35041 catatcctcg ttattaaaaa atgagacata caaaacaaaa taccataaat atctggaaga
    35101 gatagtaaca aaatacctag attcagacta tttagagaat atgacaacaa aattgcatga
    35161 catgatagca tcatatgtaa aagaagaccc aacagcattt tatacttatg aagaatttga
    35221 aaaaaatata acatcttcaa ttgaagattc tagtgataat aagggatttg gtaataaagg
    35281 gtttgacaac aataactcta ataacagtga ttctaataat aattctaata gtgaaaataa
    35341 gcgctctgga aatcaaagtg atgaaaaaga agttaatgct gaattaacat caagcgtagt
    35401 caaagctaat acagataatg aaactaaaaa taaaactaca aatgatagtg aaagtaagaa
    35461 taatacagat aaagataaaa gtggaaatga taataatcaa aagctagaag gtcctatggg
    35521 taaaggaggt aagtcaatac caggggtttt ggaagttgca gaagatatga gtaaaactat
    35581 aaaatctcaa ttaagtggag aaacttcttc gacaaagcaa aactctggtg atgaaagttc
    35641 aagtggaatt aaaggtagtg aaaagtttga tgaggatatg agtggtatgc cagaaccacc
    35701 tgagggaatg gatggtaaaa tgccaccagg aatgggtaat atggataagg gagatatgaa
    35761 tggtaaaaat ggcaatatga atatggatag aaatcaagat aatccaatag aagttggagg
    35821 ttttggtaat agaggaggag gctctgtgag taaaacaaca acatacttca aattaatttt
    35881 aggtggagct tcaatgataa taatgtcgat tatgttagta ggtgtatcaa gggtaaagag
    35941 aagaagattt ataaagtcaa aataagatta aaattgaata taaataattt taatactgtt
    36001 aagtctaaat atttacttag cagtattttt tagaaaataa tgtgtttgat taataatata
    36061 aggtaataaa ttgataaaaa ttaaatacag catattaata atacataata aagtaataaa
    36121 aaactgttta agtataataa cttatattta gacagttttt ttcatttata aataatataa
    36181 atgaaattga aaacatttga aggatagaaa ttggttggat aaatgtataa attacttcac
    36241 caaaaaataa tgacaaaaac tgtaactaag ttgtaataaa atggtagtta tttagcataa
    36301 aataatgtat catagaagta tattataaaa ttaataaaat aagatttttg taagaaaact
    36361 gctggctttt gatatttaga gtgagtagtt aaattatgtt taggaggagt agaatttgtt
    36421 gcaaaaagta ttatggaaat ttttaaagct agtagtcggt ttatttatat gttcagttgg
    36481 tatagtattg acgataaatt gtaaccttgg attatctccc tgggatgtat ttcatcaagg
    36541 actttcaaat catataggaa taactatagg aactgcttct ataattgtag gctctatagt
    36601 agttattgct gatgtcgttc ttggagaaaa tgtaggatgg ggaactgttt ttaacatgct
    36661 actaattgga ttttttatgg atttactttt atatagtaat ttaattccag aggctgataa
    36721 tttatttgta ggaataatta tgttgatatt aggattggtt cttttgtctg ttggaatggt
    36781 attttatatg ggaagtggtt taggaagtgg acctagagat ggtttgatgg ttgcaattca
    36841 aaagaaaaca ggaaaatcac ttaaattaat aagaggtact atagaagttg gagcattaat
    36901 agtaggattt ttattaggtg gaaaagttgg tataggaact ataataagtg catttggatt
    36961 ggggtatttc acacaaatgg tatttggctt atttaaatta gattgtagta agattaaaca
    37021 tagatttata gtagatgata taaaatttat caaagtgtat atgagtggtg agaaaaaagc
    37081 tgctgttcaa aatatagtta agtaatttaa gaataaattc aacgaaatgt taagtatttt
    37141 aaattaacat tttgtttaga tagataaatt gaatattaaa agaatattaa aatatgagga
    37201 ttgctagaac actataaaat atagatttct agcaattttt tatttgttca atattttttt
    37261 agtactagaa gtcttattct ctatttaatg aatgaattaa tttataatta gagatactaa
    37321 actttataga tattaatata aacaccttta aactgtgtat tttccaaagc ctttaaaatg
    37381 cttgtattta ttctaaataa aaaaataaaa aaatgtcaaa aaaactcttg tattatatcc
    37441 aaattttata tataattacc tatgttgttt agaaatttta aactcaatgt ttagtaaaca
    37501 aaatgtttag taaaataaaa cagaaactag gaggtgcaac atggatatag gtgaaaagat
    37561 aaaaagatta agaacagaaa aacaactgac ccaggaagag ttagctaata gatgtgaatt
    37621 gtcaaaggga tttatttctc aattagaaaa taacttaaca tcaccatcca tagctaccct
    37681 tatagatata cttgaaatac taggtacaaa tttaagggaa ttttttaatg aaatagatga
    37741 tgaaagaatc agttttacaa aagaagatat gtttgaaact gaagatgaag atttaaaata
    37801 taaattaaag tggttaattc caaattcaca aaaaaatgaa atggagccaa taataataac
    37861 attgtatcca ggaggacagt ataaagaaga aaagccacat gaaggtgaag aatttggata
    37921 tgtattagca ggttcaatat atgtccatat aggcgaaaag aaaaataaag taaaaaaagg
    37981 agagagtttt tactttagac cgaaagcaaa tcactatata tcaaacgagg gcaaaactac
    38041 agcaaaagtg atttgggtaa gtacgccacc atcattttag aatagaggtg tttaataatt
    38101 ggtagaaaat ataatagaat taagggatat atctaaacat tatgaagaac ttactgtttt
    38161 agataatttc aatttagata taaagaaaaa tgagtttcta acattgcttg gaccaagtgg
    38221 atgtggaaaa actacaacat taaaaataat agcaggattt gagtatgctg atgatggtaa
    38281 agttttattt gaaggtaagg agataaataa tttgccacca tatgaaagac aagtaaacac
    38341 agtatttcaa aaatatgctt tatttccaca catggatgtt tatgaaaatg tagcttttgg
    38401 attaaaaatt aaaaagactc caaaagatgt aatagatgct aaagtaaaag aggttttgaa
    38461 acttgttgca ctagaaggtt ttgaaagacg acaagttgaa tcattgagtg gaggacaaca
    38521 acaaagaatt gcaatagcaa gagctctagt caatgaacca aaggtattat tactagatga
    38581 accacttgga gcacttgatt taaagttaag acaagagatg caaatagaat taaagagaat
    38641 ccaaaaaaaa ttaggaataa catttgtttt tgtaactcat gaccaagaag aggctcttac
    38701 tatgtcagat actattgttg taatgtataa gggcaaaatt caacaaatgg gaacaccaca
    38761 agatatatac aatgaaccta aaaattcatt tgtagctaag tttataggtg aaagtaacat
    38821 atttgatgga attatgatag aagattataa agttaatttc tgtaatagag attttgagtg
    38881 tgttgataaa ggattcgaaa aaaacgaaaa tatagaagta gtaataagac cagaagatat
    38941 aaaaatggta aagccagaag aaggaatgtt aaaggggaaa gttacatcta cagtgtttaa
    39001 aggagtgcat tacgagatag aattgaatga aaatggaaga ttgtggatac ttcataatac
    39061 taaaaatgct gaggttggga ctgaactagg catggatata tatccagaag atatccatat
    39121 aatgagaaaa gagaataact aagatgaaaa gaaaatcttt tttagcatat ccatatgtag
    39181 tttggagtgc gatatttgta ataattcctt taatattagt agtatttttt agttttacaa
    39241 aagaatcagg tggaggttat gcctttacac ttgagaatta taaagaagta attgacccta
    39301 tatatatgaa agtttttggg cgttctattc ttttagcagg aggagctaca ttaatatgcc
    39361 ttatagttgg ttatccagtg gcatatataa tttcaaaggc tcgtgtaagt agaagaggtt
    39421 cattaatatt attgtttatt cttcctatgt ggatgaactt tcttttaaga acatatgcat
    39481 gggttgctat attaggaaaa aatggacttt taaatacatt tttaggttgg tttggaatac
    39541 aaccattagc aattttgtat actaattttg ctatactttt aggtatggtg tataactttt
    39601 taccatttat ggttcttcca atatatacag cactatcaaa gatggataat gatttgataa
    39661 acgctgctca tgacttgggt gcaaataata tgacagtttt tagaaaaatt atatttcctt
    39721 tgagtttgcc aggtgtaatg tctggaataa ctatggtatt tatgccagca gtcactactt
    39781 ttgcaatatc aagactgtta ggtggaggta aaataatgct ggttggagat ttgattgaac
    39841 aacagtttac agttgttgga gattggaact ttggttcagc tatatcgata tttatgatga
    39901 tagtaatatt aatatctatg tctataatgt caaaatttgg agatgaatct gacaaagaag
    39961 gcggtgggtt actattttaa aattaaagaa aataacttct aatatatatt tagcattagt
    40021 attcttattt ttgtatgcac ccatatttgc tttggtacta ttttctttca atgattcaaa
    40081 atcaatggca agatggaatg gatttacatg gaagtggtat ggtcaattac ttcaaaatga
    40141 gagtataatg agtgctttat attatactat tgtaatagct atattagcgt ctgtaatatc
    40201 tacaatagta ggaactataa gtgctatagg aatacataag atgagaggta agagtaagaa
    40261 attaatacta aatgtaaact atcttcctat tttaaataca gagatagtta cagcagtagc
    40321 tcttatgagt ctgtttgtat ttgtaaaaat ggaatttgga tttacaacaa tgctattggc
    40381 acatataatg ttttgtttgc catacgttat actttcagtt ttgccaaaaa tgaagcaatt
    40441 acctgataat atagaagatg cagctatgga cttgggagca acacctatat acgctcttag
    40501 aaaagtaatt ttaccacaaa taaaaccagg tatagtttct ggatttttaa ttgcatttac
    40561 tatgtcaata gatgacttta taataagttt ctttaatgct ggaaatggtg taagcaatct
    40621 ttctatagaa atctatggaa tggctagaag aggtataaaa cctgaaataa atgcattatc
    40681 aacaataatg tttgcagtgg ttctaggttt acttttacta gctaataaaa aagaatctat
    40741 agtaaggggg attaaataat gattaagttt aaaaaagcaa tatcccttat agctgtaggt
    40801 atgatgacag ttactttatt tacaggatgt aataaagcaa ctgattctac aaaagtttta
    40861 aatgtatata atgttggaga ttatatagat gagtctctta tagataagtt tgaaaaagaa
    40921 acaggaatag atgttcaata ttcaacttat gatactaatg aaatgatgta tcaaaaagta
    40981 aagagtggta gtacacacta tgatttagta tttccttcag actatatggt agagaaaatg
    41041 aaaaatgaag gtcttttgga aaaattagat tttaagaata tacctaatat gaaatattta
    41101 gataagagtt ttttaaatcc tgtatacgac aaaactaatg aatatagtgt tgcatatatg
    41161 tggggaactc ttggaatatt gtacaataag aaagaagtta aagaccctat ggatagctgg
    41221 aatatacttt ggaatccaaa gtataaggga aatataatga tgtttgactc tgttagagat
    41281 actataggga taactcttaa aaaattagga tatagcatga atagtgtaaa tccaaaagaa
    41341 ataaatgaag ctaaaaatct tttaatgaaa caaaaggatt tagtattggc ttatgtaaat
    41401 gatgaaggta aggatagatt gcttggtgga gaagtggcaa tgggtatgct gtattctgga
    41461 gatgcagtta cactaatgga gcaaaatcct gaccttgatt atgctatacc taaagaggga
    41521 actaataaat gggtagatgc tatgtgtgta cctacaacag cacaaaataa gaaagaagct
    41581 gagctgttta taaacttttt attagaccca gagaatgcaa aagtaaatgc tgagtacatt
    41641 gggtattcaa cacctaatac aggagcacta aaattattag acccagaaat aactcagaat
    41701 cctgttgcat atccatctaa agaagtactt gataaatgtg aaacttttga agatattggt
    41761 gaaaatataa aattatatga caaggcttgg atagagttaa aatcaaaata gggtcttgtt
    41821 gttttaagta aatttactta ataaatactt aataaaactg ttctttttta gaaaatttat
    41881 tttctaatta ttgaacagtt ttattttttg tttaagttat attcatatgc aatttaaata
    41941 gtttattaat aaatgaaaac ttatttgtat aatgacttta ataataatta gaaaaaatgg
    42001 gcaacttaat agaataattg gaggtgtaaa tttataa
//
LOCUS       DAJMZY010000026        41580 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.026, whole genome shotgun sequence.
ACCESSION   DAJMZY010000026 DAJMZY010000000
VERSION     DAJMZY010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 41580)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41580)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41580
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.026"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            complement(696..1205)
                     /locus_tag="OE968_001344"
     CDS             complement(696..1205)
                     /locus_tag="OE968_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CarD family transcriptional regulator"
                     /protein_id="HCP7218631.1"
                     /translation="MVMFLFKIDDYIMYGMTGVCKVMDITNERFTNGIKKEYYVLSPI
                     YSNNTVIKIPVDNEKVPMRKLLSKINVLSLINDIPNMDTSWIDNEKLRSEQFKKILRG
                     GKCEELIKLVRSIDNNREYVKSIGKKTHQADDNIMKEAERLLNEEFATILDISPNEVS
                     SYISSHIPQ"
     gene            complement(1416..2825)
                     /locus_tag="OE968_001345"
     CDS             complement(1416..2825)
                     /locus_tag="OE968_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218632.1"
                     /translation="MENYFDKQAKELYNKASEIINTHSMLKANRANEKFDIDIPQDFK
                     YEFFSLVDKVNLSLMEEEDNFYGYFLFQMSREIRFDISSPTGVNFKGAKYVIYFNPII
                     FLTLDIKQMETTIKHEIHHILSMHLMRAKELKGKYSTLAINMAMDIVVNKFLNNLPPY
                     ATTLEWVNLKYSLKLEPYEPFEYYVEKIQTELDLMEVDEDGEEDDSDKYGDIEIDYSP
                     ERTHDIWDESNEIDENTLREFTEKFINSSQKGKVPAYLESMISSLKNSKGELPWNLYL
                     NRIMGTVENNKKKTITRRNRRQPNRLDLRGELRSHKSEIAVALDVSGSISDEEFKQAI
                     KEVLSIVKNYNHEITIIECDNEIRRVYKVRTEKDIKDRIRIGGGTRFSPVFEYANNKK
                     INLLVYFTDGKGENKLQVIPRGYKILWVISGRGDKISLKEPYGAVKKLTKVKTNDEIL
                     EINDVRNDGYSMNSQAPIL"
     gene            complement(2829..3959)
                     /locus_tag="OE968_001346"
     CDS             complement(2829..3959)
                     /locus_tag="OE968_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HCP7218633.1"
                     /translation="MNFIDTLKSVDLILSTGEVPLIVGESGIGKTALANKLAKENDWS
                     LIVIDGNLLKEGEIGGLPTIESYVGVNSNGYKTEKKTTVYAVHNKLREIDEEISKSKT
                     VLLFIDEINRCEHTVQQELMNLILNREINGYKLHDDVKILAAMNPSSKYGSDFDYQVV
                     DMDAAQENRFVWLNMESDHTQWIKWAIDEGIERKVIEFISTFPEYLHKINEDDVRATP
                     RSYERVSKIYKVYKEKNNSIPRAVFLNVVKGNVGKVIAEEFISFIESNSEPLISYEDV
                     FLGESIDESIVERVKNESHTRLYLSAMNILKDLELNIKNDKYESNHYINRFIEFLKMY
                     PVDLMIGIMKDIRNSYIEVYKKAIENEEFVKSYFESYSLIRG"
     gene            complement(3971..4774)
                     /locus_tag="OE968_001347"
     CDS             complement(3971..4774)
                     /locus_tag="OE968_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218634.1"
                     /translation="MEKLRVIEMIKNNPNIIATIDNPTDEMKLLAIKENGLVLEYINN
                     PTREMQELAIDNNIRAIKFIDNPTEDMMIKAVNEGWSILDYIKNPTDKVIEMAINQAG
                     WAIKYAKNPSEELQLLAVRKNYDSIKFIKQPYESVQEEAVRISYDALRYIDSPSYNAE
                     LIAIKNNEAAISFITDLDKNKMLEFLKVNILVIKYILKKVSKDELESVLKEVLSKEDV
                     EEKYIRDFLNCSVIDRNSESIPIDKIMFIYKYGSKTAKKIAVDEKLKIM"
     gene            complement(5156..6037)
                     /locus_tag="OE968_001348"
     CDS             complement(5156..6037)
                     /locus_tag="OE968_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline iminopeptidase-family hydrolase"
                     /protein_id="HCP7218635.1"
                     /translation="MKITEGYMPFKGFKTYYRIVGENTEGKKPLVLLHGGPGSTHNYF
                     EVLDKIAESGRQVIMYDQIGCGNSFVEGHPELFNADTWIEELIELRKHLGLDEIHLLG
                     QSWGGMQAIWYAIEYKPKGIKSYILSSTLSSAKLWEKEQKRRISYMSEVDQKALLDAV
                     NTGDYSSKEYNDALERFMEMYCAGEVTEDSPECLRRPKKSGSEAYIVGWGQNEFSPTG
                     TLSGYEFTDRLHEIKEPCLVTSGAIDLCSPYIAKTMYDRIPNSKWELFEYSRHMPFVE
                     ENEKYIKVLTEWLNAND"
     gene            6493..7467
                     /locus_tag="OE968_001349"
     CDS             6493..7467
                     /locus_tag="OE968_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218636.1"
                     /translation="MNNINSLKVIKLSLGCSLAIFIAWLLKLEYSMVAGVIVLLTVKD
                     TKRETLKGSIGKIYGFLLCTIFSYLCFNILGYNLTSFSIFIFIIIPLCFLLNIQDVIA
                     MCVVIASHYYLQGETSIKWILNEAGIFAVGTGIGVLINMYIPTNIHKIHEVQKKLQEE
                     VSIVLIDIADIIVNPKKENGYSRDLYTLNSLIDSSISETYDNINNTLLSDTRFFLEHM
                     DIIKSQRDILENLYSYVSQLNSTPPQAHILSAFIHKIGYTEFEAETGNLLLEELKRLM
                     LSMKNQPLPVDRTEFENRAILFLCLTELKQFLVNRKHAQILRDNNFYK"
     gene            complement(7583..8644)
                     /locus_tag="OE968_001350"
     CDS             complement(7583..8644)
                     /locus_tag="OE968_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
                     /protein_id="HCP7218637.1"
                     /translation="MKKIRKLTTKLLITTIVLISGMSMTVYGMTAKEVTAKTPKSYVT
                     GTNSVYGPKLSQAQLNSVAQATADFMNKKITKNMTTDAKILVAYNHIKNNTTYVDWNA
                     VEGANTAYTLVTKKGACSGMARSMKALCDAMGIESYYVHSTSNDHQWNLIRFGDGRLY
                     HVDIDANKSAGKDIIYKSLSHPLPFDKTAYPKVGAIVQTVKPEQTQKPAPPGKHTMLP
                     HQEGAKAVGNFGKKGEDINEKHVMYEGVRCSVVNSSVNTITFTGSESNLDPSNLTIAV
                     IGFMNTPYGMFALAPEGKPVEYPFKYDKPFSLDFSGKNRSGAELAKYCKKNDVTIKIE
                     ITDEKANIGLGQIMYVRYE"
     gene            complement(9256..10107)
                     /locus_tag="OE968_001351"
     CDS             complement(9256..10107)
                     /locus_tag="OE968_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HCP7218638.1"
                     /translation="MSCILKLKQIYEDLTEVDKKIADYILNNTEAISKLSVSELASNS
                     KTSTASIVRFSRKMGYSGFGDLKIEIAKDLMGKENEYTYVDENYDCNIDSVINKITNK
                     NIETINQTRLLNEKDIIKEAVEQIIKAKNVYIFGVGGSALVALDLQMKLLRINKQAFT
                     SLDSHTQLMVSSNVDKEDIAIAISYSGESKEVIKSIENAKLKGCKVICITKYSDNHLS
                     KISDLKLVVPNIEKRLREGAISSRIAMLTLIDIIYISIIQENLNEAEQKLQETKRILD
                     YLNINNA"
     gene            complement(10124..11044)
                     /locus_tag="OE968_001352"
     CDS             complement(10124..11044)
                     /locus_tag="OE968_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA reductase"
                     /protein_id="HCP7218639.1"
                     /translation="MYFLGVDGGGTKTTFTLVDEELNIVGTITKGTCHYNQIGFDNLT
                     KLLITGLEEVCKDAKINVEEITYAFVGLAGYGKIKEVLYALEVATKNAYSHINYTLGN
                     DVEIALAGSLNGEKGINIIAGTGSIAQALDKDGNLHRCGGWGYVLGDEGSAYYIGMAT
                     LKMFTMQSDGRCSKTKLYDLIKRHLNIENDYDIIKYVNDEIQGDRIEIAKFATICLKA
                     VIEGDNTASKIFDDAAYELSRLIIGLEHHFEQGTKIKVSYSGGVFKSGDLILEPLKKY
                     LNKTRFGIVRPVLTPDLGACLLAKKKYYSK"
     gene            complement(11154..12068)
                     /gene="murQ"
                     /locus_tag="OE968_001353"
     CDS             complement(11154..12068)
                     /gene="murQ"
                     /locus_tag="OE968_001353"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HCP7218640.1"
                     /translation="MLIKTLENLVTEGRNKNTLQIDKEDTLGIIELINNEDKTVAYAV
                     EEQKESIAKAVNIIVDRMKQGGRLFYIGAGTSGRIGILDATECPPTYGVDFELVQAII
                     AGGNQAIFKAIEGAEDDKELGKQDIIDRGVTSKDVICGIAASGRTPYVIGAMEYAKEL
                     GCAVLSITMNPNSEMSKKADLPINIIVGAEVIMGSTRMKSGTAQKMVCNMLTTASMVK
                     MGKVYSNLMVDVKTSNEKLVERAKRIIMIATNVKYDVAEKFLEEADNSVKLAIFMIKS
                     GLDKDSAKSILDRQEGYISEALKSIEKL"
     gene            complement(12167..13264)
                     /locus_tag="OE968_001354"
     CDS             complement(12167..13264)
                     /locus_tag="OE968_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HCP7218641.1"
                     /translation="MGRLGISIYPEKTTSKEIYDYIDKAAENGFTRIFSCLLSVKDTK
                     ENIIKKFKRINEYAKFKGFEVILDVNPRVFGELEISYKDLTFFKKTKADGIRLDIGFT
                     GSEEALMTFNPQNLKIEINMSNNTNYIDTIMDYQPNKENLTGCHNFYPHRYSGLNLEH
                     FIKCTERFNKYGLRTAVFVTSQNETTFGPWPVTDGLPTIEMHRNLPIDIQVKHIIAMN
                     NINDIIISNCYPTYEELKVLGSMRKDMVTFDVAIEENIREVEKKILFEEIHFNRGDIS
                     DSLIRSTQSRVKYKGYKFELFNTPKIIKRGDIVIESSEYGHYAGELQIALTDMKNSGK
                     SNVVGYIRKEELFILDYIKPWQKFNFKPSTK"
     gene            complement(13497..14843)
                     /locus_tag="OE968_001355"
     CDS             complement(13497..14843)
                     /locus_tag="OE968_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCP7218642.1"
                     /translation="MLDKFTEFLDTKLSTSMARLAEQRHLRAVRDGIVASLPLIIVGS
                     FFLILAFPPLPDSWGVTQYLKENAVTILLPYRMTFFIISVYSTFGIGYSLAKSYKLDG
                     LTGGLLATATFLLTIVPTAIEGLTPELLKIVEKSPELLAWYNSIPQGWQMPMANLGGG
                     SMFVAIVTSIIGVEIYRFTDKSKFKITMPEAVPASVTRSFEALTPAALIIILMAIVTY
                     FLGFDWHGFIAKLVTPLVSATDTLPSVIILIFLITFFWSFGIHGVSIIGSLARPLWIQ
                     LLDANTASYAAGQAVPGIAAEPFFQWFIWIGGSGATIGLALLLAFRAKSAYGKSLGKA
                     TVIPAIFNINEPIIFGAPIVLNPILIIPFVVAPIVMATVSWFAMSANLVSRVVVTAPW
                     TLPGPVGAYLATGGDWRASVLNLLCIAISIIIYYPFVKMYDKRLLHEEKVEEQEAY"
     gene            complement(14932..15240)
                     /locus_tag="OE968_001356"
     CDS             complement(14932..15240)
                     /locus_tag="OE968_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCP7218643.1"
                     /translation="MRVLFVCSSGMSSAIAVNALQKEGAKNGIDIDVLAVGTQEFENE
                     VKNGWDIAMVAPQVRHRFDYLKAFADEVSVPCALIQAQAYSPLGGPKLLKQVQELLSK
                     "
     gene            complement(15502..15900)
                     /locus_tag="OE968_001357"
     CDS             complement(15502..15900)
                     /locus_tag="OE968_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218644.1"
                     /translation="MSNNKKKKRKKNNNYKNAKSTKSNKNTKKQMEKNQRTDYNIPTI
                     SFKSGLILIVSSLVSTVVFPLLLSIFGIDNRFGVVIGNSLITSFAVAYTRYFVETKRG
                     FSLGFFRLYILFALSFAIIGYFWIYKGIHI"
     gene            complement(15902..17062)
                     /locus_tag="OE968_001358"
     CDS             complement(15902..17062)
                     /locus_tag="OE968_001358"
                     /EC_number="2.7.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anhydro-N-acetylmuramic acid kinase"
                     /protein_id="HCP7218645.1"
                     /translation="MITMYSVGLMSGTSLDGVDAVLAEISGNGRNTKVKQIEFITLEI
                     PKDIKDEIRKCCIEEESSVDLICSLNFKLGYLFSKAVKSVCHKANFHIANLDFIASHG
                     QTIFHIPRSYNNFVSSTLQIGEPAVIAYETNTKVISNFRVMDIAAGGEGAPLVPYSEF
                     LLYSDNNKNLALQNIGGIGNITIIPKSCNIDDVFAFDTGPGNMIIDGVCQRLFNRKYD
                     KNGYFASKGKINEEMLKDLMSHKYLSQAPPKSTGREVFGQVYLDNMLNKYKHVDKYDL
                     IATVTMFTAKAIYYNYKNFILPKVNVDTLLIGGGGAHNLTLIGYIKELLLEVEVLTQD
                     EYGYSSDAKEALAFVILGNETLNNSFSNVISATGAKNKVILGNITPKPFGGK"
     gene            complement(17493..18512)
                     /locus_tag="OE968_001359"
     CDS             complement(17493..18512)
                     /locus_tag="OE968_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HCP7218646.1"
                     /translation="MLVKYLKGRSKYIALPLVVVSIINIYLFAIDIFKNKYSELIYLD
                     FLVLFIIMVFFVIDYINFRNSYTNLYNCIENSGEIDSYLVDGQSFEENLIKDIIENLK
                     IKNNSDIETYKQSLKELDEYIAKWVHEIKIPISSLSIITDRLSSIEDSLDIKNQVAKI
                     NFLVNSILYSSRSNTMFEDVFINKFNLEKLVKMSIKNNSFLLIKNNVEVSLNELENDV
                     YTDSKCMSYVLDQIINNAIKYSKEVGKIEFNSKKLENGVVLSIKDFGIGINEEDISRV
                     FDKGFTGKNGRNQLYKSTGMGMYFVKKMIDSLGHEIEVCSKIGSYTIFNIYFYDISDY
                     LSIDS"
     gene            complement(18506..19186)
                     /locus_tag="OE968_001360"
     CDS             complement(18506..19186)
                     /locus_tag="OE968_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCP7218647.1"
                     /translation="MYRILLVEDDIDLSKEIALALEKWGFKVELIDDFEVVLDEFIDK
                     KPDVVLLDVNLPLYNGFYWCEKIRAISNVPLIFLSSRDSDMDLIMGINNGADDYITKP
                     FSIEILVTKINGIIRRVYNYSDSNSILYCEDLMFDVGKGIIKHKYKDKSIELTKNEIK
                     ILTLLLKNKNRVVSRESLMMTLWDNDEFVTYNALTVNMNRLRSKVKELGFDDFIKTKK
                     GIGYIIQC"
     gene            complement(19338..21245)
                     /locus_tag="OE968_001361"
     CDS             complement(19338..21245)
                     /locus_tag="OE968_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HCP7218648.1"
                     /translation="MSILGIAYNNFKSNIRTYLAFFISMVFSVVVLTNFELLRYGDAI
                     NVLQEENKKFTLSVLVAVIMILSVFLFFFIWYATNIFFKNRSKEIGILSFMGLDLYTI
                     GKIYFVENMLIGISSCITGIIIGIITSRFFQVVIIKLSGFNIKVSNGLSIEAILYATL
                     IFISIFIIMAVKGFITICRSSVINLINISKKQEKIPKVGIGIYILAIVSIIVIGYGYY
                     LSTNIRTGDITSVLPVIGIIIVGTYGLFKSVMPVIFDIIIKNKKILFNGNNIIAINNI
                     NYRLNKNYKTYAIIAIIITTTISTLGASVAMKHIHKNAQEQRNVYTISIVSMDKDEVN
                     KKQIENIIKDTNKIKYSVNPELTILKKTDIKEAYDTTDTIMKYSDFCNTLKVNGNDKE
                     LKEYGERLVSGNNVIELKSPQTIASIATKEAKIKLDGQLYNISRGEVKVPVLGTGLNQ
                     SIIVVNDDTYFKLRDKGQQVYFYGAKVFQEENSQVMFNNIEKNLSLKNGYIQNGYKAQ
                     GESQWMKFAYVVLVFLFLVFAIVAGSIIYMKIYSDAYEDKEKYKILLKIGTTEKDINR
                     AILKEVAIFYTLPMLSATISSYFALRLAGDLLMTDLFGIYILSLVICLIIFIIYGAVS
                     VNKFKSVVYKN"
     gene            complement(21246..21998)
                     /locus_tag="OE968_001362"
     CDS             complement(21246..21998)
                     /locus_tag="OE968_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCP7218649.1"
                     /translation="MKEILKIKNISKDYGIKGFKTNVLKNISLTVNEGDFISIMGPSG
                     AGKTTLLNLMSTLDKQTSGEIILDGINISKVKNNELSKLRREKIGFIFQDYNLLDNMK
                     LMDNIALPLALGKKKSKEIEAKVFSIAKKFGLENHLDKYPYQLSGGQKQRGAAARSLI
                     TNPTVIFADEPTGALDSKSAYELLESLEKINRENNATIIMITHDPLTASYSNEVYMIN
                     DGNIKCKLNKGNSRKEFYGKIMDMLASMGGEM"
     gene            complement(22314..23468)
                     /locus_tag="OE968_001363"
     CDS             complement(22314..23468)
                     /locus_tag="OE968_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCP7218650.1"
                     /translation="MINKAIKFKFIIFYFFSYIIFAFASTKFTPFLSKLGYSAFERGI
                     ILSSYAITNILFQLLFGVLADKYQTMKKIVLISLSVYGIASVIMFSTESATFIIYLLL
                     VALSGGLLNTCCSLYDTWIIGCGDNINNYLSFIKTFGSIGWAIGSMVASYLILRFSYF
                     GLSVAIGLIVVLLIINILLLPDIEKINKKINVTNKDIIELLKDKKYILLVCILFLLYS
                     MVVANNCTVIDKMIALNATNSQISLKWSLQSLLEIPTYLAGSYLLKKYSSLNLLKLSA
                     IMITVQFLLFALTNDSNIIIILCVFQVFSTPLILITSKRLIFEVSPKKLRSSSQLIAL
                     SIFMGGSSLIIPTVAGFLSINIGYNYTLMVLSLFGCLAYCLIVLLNYLQE"
     gene            complement(23471..23938)
                     /locus_tag="OE968_001364"
     CDS             complement(23471..23938)
                     /locus_tag="OE968_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HCP7218651.1"
                     /translation="MFFKRKKEAITINSYIDGKIINLGEIPDKVFSTKVMGDGFAMIA
                     KDNILKSPTKGVISFIAQTNHAIGIKLQNDVQILIHIGLDSATTKKENFKLEVKQGQE
                     VNMGEKLVEIDNKLLENTLYIPLVIVENPNTVKYHLSNLNQEGNSGIKVINFD"
     gene            complement(23952..24440)
                     /locus_tag="OE968_001365"
     CDS             complement(23952..24440)
                     /locus_tag="OE968_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218652.1"
                     /translation="MITNKIKNITAVLKDENIFLSVVMVCFLILPVLYIVYLELTSLF
                     TNISFSQLLNNDVNASLNLISNFSAVYSAYVIYNIKKNKEIKENMIAFYLVLLGQIFQ
                     IYTITIVIMFTYIYKFVGIKQIISSIKELQWGKSYKALFSSIAVCLISLFVMIIRIKL
                     IM"
     gene            complement(24454..25785)
                     /locus_tag="OE968_001366"
     CDS             complement(24454..25785)
                     /locus_tag="OE968_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-alpha-glucosidase"
                     /protein_id="HCP7218653.1"
                     /translation="MERKRQRILIAGGGSTYTAGIVTMLIESVAKFPIESIKLYDNND
                     ERQRKVAEACAIIVREKNPEIKFSYTTNPEEAFTDIDFVMAQIRVGLYALREQDEKIP
                     LKYGVVGQETCGAGGIAYGLRTIGPIIEMIDYMEKYSPNAWMLNYSNPAAIVAEACRV
                     LRPNSRIINICDMPVCLEEIFARVLGLNSRKDFDVRYYGLNHFGWWTSIKDKEGNDLM
                     PKLQEYCAKKGYEEFTPQGQHKESSWLETMRAAKDLLEIEPTTLPNTYLKYYLMADET
                     VEHANPNYTRANEIMDRREKDTFEECERIIKNGTARDTWFDASEHSQFIVELACALAF
                     NTQERFLLIVPNNGAIENFADDAMVEIPCLVGKDMVEPMSIGKIPTFQKGLMEQQVAS
                     EKLAVEAWIEKSYQKLWQSFTMSKTVPSAKVAKEILDEMIVANKDFWPTFK"
     gene            complement(25799..27364)
                     /locus_tag="OE968_001367"
     CDS             complement(25799..27364)
                     /locus_tag="OE968_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003233606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HCP7218654.1"
                     /translation="MMKKIQRFGGAMFTPTLLFAFAGIMVGFSIVFQNQSIMGSLATP
                     ENIWYQFWGVISSGAWMVFNQLPLLFAISLPIALAKKQQARACMEALATYLTFNYFVG
                     SMLSFWGKSFGVDFAAEISAGSGLVSIAGIKTLDTGMVGALLISGIVIYIHNRFYDKE
                     LPDFIGLFRGSSLVVAICFFVMIPVALLTCFIWPHIQNVIRHLQTFFINSGNIGVWCY
                     AFLQKILIPTGLHHFVYAPICYDSVVVPGGTSVYWATHIQDFQTSAKTLKEMYPIGFS
                     LSGLSKVFGSLGVFGAFYVTAKPEKKKKVLGLMIPATLTAVLTGITEPLEFTFLFVAP
                     LLFLVHAFLDACLQTISFALGVVGDFGGGIINWVVLNWLPLGMYHWKVYVVQVVVGII
                     FSFIWFFVFTFLIKKFDMKTPGREEDSEETKLYTKNEYLETKDEKGNKLSKASQQASE
                     YIKLVGGAENVVDVTNCATRLRLTLKDDSIISKEEDFKAVGAHGLVHNGKAIQIIIGL
                     SVPSVREEFENLL"
     gene            complement(27534..28319)
                     /locus_tag="OE968_001368"
     CDS             complement(27534..28319)
                     /locus_tag="OE968_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HCP7218655.1"
                     /translation="MRLEEMIFLNYNKLNDTDLLIWKYITANKKHCSKMSINELAMKC
                     NVSRATITRFVKKLDLKGFSEFKVLLSWESEKVHVIENQSFDIACNSIIKYVEDQKNK
                     DYDALCKLLYESRTIYAYGSGDIQNVVAKQIKRMFLSCQEIIYDFEGRTFDDSFYNIV
                     SKNDVMIIISLSGENENTLNIARRLKLIGTKIISITEFKNNTLTDLSDESIYISATNI
                     SFLQMHPSYKLTMLYFILIELLFIKYSIYKRHRMITEGIDCKL"
     gene            complement(28486..29685)
                     /locus_tag="OE968_001369"
     CDS             complement(28486..29685)
                     /locus_tag="OE968_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S41"
                     /protein_id="HCP7218656.1"
                     /translation="MKKKVLFLVIILAFIILLGNSTYSQKNQLSEEEKVDDFNYVYNV
                     VKTGYPYLGVNKRLNNIDWLANKDEYTKRIKNTENDEEFIEEMSSILSDLNNKHTEVI
                     DNKKRYELFKKSYSNNDWYDFLNDKKVVDRYDSMNLKIKMPDDIFVKKELILKDVIKG
                     QIGYMYLPSMSSKNGSINNDLKIIGDYIDTLEKHKALIIDIRGNLGGSDSYWQGIVSK
                     LIKNDVKINGYRIYRNNNEIVKQYTNARNIKLNPVENLPTSVKENAPKEIIKDFNDFE
                     DTSYTIKSTDDSKFKGNIYLLVDRKIYSSSESFAMFCKETKFATLVGETTGGDGGCID
                     PVLFNLKNSGLIVRMASCMYLNKNGICDEEFKTIPEFKVKDCKRTADFKDDNCIRKAL
                     ELENINY"
     gene            complement(30207..31544)
                     /gene="xylA"
                     /locus_tag="OE968_001370"
     CDS             complement(30207..31544)
                     /gene="xylA"
                     /locus_tag="OE968_001370"
                     /EC_number="5.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylose isomerase"
                     /protein_id="HCP7218657.1"
                     /translation="MSEIFKGIGQIKFEGVKSDNELAFRYYNPEQVVGNKTMKEHLRF
                     AMSYWHTLCGEGNDPFGVGTVERPWNNITDPIEIAKIKVDAGFEFMSKMGIEYFCFHD
                     RDIAPEGRDLEETNKILDEIVEYIKVNMEKTGIKLLWGTANMFGNPRFVHGASTTCNA
                     DVYAYAAAQVKKAMEITKYLGGENFVFWGGREGYETLLNTNTELEMDNFARFLQMAVD
                     YAKEIGFTGQFLIEPKPKEPTKHQYDFDTATVLGFLRKYNLDKYFKMNIEANHATLAG
                     HTFQHELNIARINNVLGSIDANQGDLLLGWDTDQFPTNIYDATLAMYEVLKQGGIAPG
                     GFNFDSKVRRASFEVEDLFLAYIAGMDTFAKGLLIAHKLLEDEVFENFTKERYASFSE
                     GIGKDIVEGKVGFKELESYALQMPVIKNKSGRQEMLEAILNRYIYEVDTISNK"
     gene            complement(31640..33190)
                     /gene="xylB"
                     /locus_tag="OE968_001371"
     CDS             complement(31640..33190)
                     /gene="xylB"
                     /locus_tag="OE968_001371"
                     /EC_number="2.7.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylulokinase"
                     /protein_id="HCP7218658.1"
                     /translation="MKLEYVLGVDIGTSGTKTVLFDKLGNTIKSCTYEYPLIQEKSGW
                     AEQDANDWWKAVVESIREVVQSSNISSECIKGIGLSGQMHGLVMLDNEGKTLRNSIIW
                     CDQRTVKECEEITDLVGEERLIEITANPALTGFTASKILWVRNNEPDIYKNTNKILLP
                     KDYIRYKLTGEYATEVSDASGMQLLDIRKRDWSDEVLEKLNIDKNLLGKVYESQEITG
                     YVTRDVASLTGLKEGTIVVGGAGDQAAGAIGNGIVKDGVVSSTIGTSGVVFAYTKEPK
                     IDKEGRVHTFCHAIPNTWHVMGVTQGAGLSLKWFKDNFCQSEVEVSNSLGEDVYEIIN
                     NQVSQVPTGCNGLLYLPYMMGERTPHLDPYARGVFFGLSPIHSKKEIARSIMEGVSYS
                     LKDCMDIIENLNIDVNEVRASGGGGKSKVWRQMQADMFNQDVYTINSSEGPALGVAIL
                     ALVGAGIYENIQKACDAIIKTSTKLEPISENVDTYNIYHRLYKRIYKSLKDDFKLLDE
                     VVNAKINN"
     gene            33398..34558
                     /locus_tag="OE968_001372"
     CDS             33398..34558
                     /locus_tag="OE968_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HCP7218659.1"
                     /translation="MVTDKYTIREMNERLVLEQIIKNGPISRASIASTIGLNKATISA
                     ITKKLIDESLVHEIGIGNSTHSGGRKPILLVFNKCAGISLSMDIGYDYIFSSLSYLDG
                     TIINSKKLTDIQVSKDNVIQLIDEIINSYNISKIDTPYKVIGLTLAIHGITCENKVLF
                     TPYYNLNEIDLYSILSKKYDFPIHIENEANLTALAENTFSTVHNSLLSLSIHSGFGSG
                     IIINNKLYSGRNGMSGEIGHTIIMPNGKLCPCGNRGCLEQYCSEKKVFEQLSSLENIP
                     KIDSDIVKQLYYEDNHNAKKVIHEFCSYLTIAINNAITTYAPEIIYLNSQIISDIPEI
                     LQITKDMLVSSFNKGINIEISSLGSEASLYGGSAVNIKSFLNIQNLTLINEI"
     gene            complement(34714..35118)
                     /locus_tag="OE968_001373"
     CDS             complement(34714..35118)
                     /locus_tag="OE968_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HCP7218660.1"
                     /translation="MNSIILMSHGNMAEEVLNSAKMIIGDSIDYPTVNMKQDDGIEGT
                     IEKLKKALEVYKESSEIIIMADLLGGTPCNAALLVANNDSRIKIISGLNLGMVIESAF
                     LDTKELAAKLEKIGKDNISMVEQNASLLSDDE"
     gene            complement(35139..35621)
                     /locus_tag="OE968_001374"
     CDS             complement(35139..35621)
                     /locus_tag="OE968_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCP7218661.1"
                     /translation="MEMKGIKNIRIDDRLIHGQVATMWSNKLGVTRLMVVNDAVANNS
                     VQKQVLRMATPAGIASSIITEETAIKNITAGKYEGQNVLLIVKSPVDLIPFVEAGFKI
                     HNINVGNMSSRKDTTVLRPNISVTEEEKEAFKRLLDEGIEITTIMTPDDKKTYLVDIL
                     "
     gene            complement(35641..36450)
                     /locus_tag="OE968_001375"
     CDS             complement(35641..36450)
                     /locus_tag="OE968_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HCP7218662.1"
                     /translation="MSDKVSLNKSNEKVKKSVLWRWFFTSSVSSNYEKMQALAYCYAV
                     LPFLKVVYKDNPEKLQSAVLNHLQFFNTNPWVAPYILGINVAMEELSSEETEEAVASI
                     KTGLMGPVAGLGDSLFVVIPWTIFGAIAANMAIDGSPFGILLWIVVSVALKLLSIPLF
                     NAGYTSGTKLISSIEKSLKILTESTSILGLMVVGALIPSVVKANVALNFQQGDFTMKG
                     QEILDQIMPGLVPAILVVIVYWALKKNIKPIYLILGVMVVSIILYALGILK"
     gene            complement(36443..37222)
                     /locus_tag="OE968_001376"
     CDS             complement(36443..37222)
                     /locus_tag="OE968_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCP7218663.1"
                     /translation="MEPQLWQLLLIVLYGFFINYEKNSTMFGTYQPVTAGFITGLILG
                     DINTGLYIGGTLQLLSLGISNFGGASIPDYQTASIVATFITITTKQEASVGISIGIPV
                     ALLMVQLDVLRNTIGIWLVHKAEDGAKKGNYKNITYMQMLGVLLTAATTGIPVALSVI
                     FGPSLINTILKYTPEWLTGGLTVAGGLLPAVGIGLLLRYLPAKEYFSYLVIGFVLAVY
                     MKVPLLGVALIGGAIALIIYKKNLENQEQQYTVVGGMDEDE"
     gene            complement(37222..39300)
                     /locus_tag="OE968_001377"
     CDS             complement(37222..39300)
                     /locus_tag="OE968_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HCP7218664.1"
                     /translation="MIKISEDYIEKRFDNELLRIEAWGKNSLRIRSFVDQNFVDENYA
                     LNEKPKLNKDDITINKNEDGSAIIKNGKIKAVLDHRDRITFYNDKNEILLKEYIRLRA
                     VKHDDGGEDVGTIEITKDFNSTLKLKSREYRPSYSGEFEVTTRFESEPSEKIFGMGQY
                     QHKFLDLKNTVLELAQRNSQISVPFYISSLGYGLLWNNPGIGKVSFAKNMTEWKMFST
                     NFIDYWITCGESPKELNKNYSQVTGTVPMMPENLLGLWQSKLRYRTSEEVLDVVKEYS
                     KRGIKLSSIAIDYFHWPKQGEYKFDLDYWKNPKELVKKLKEEYSVEPIVSVWPTVQSD
                     AENYNDYLENGYLVNVNRGVRMTMQIQGNTVFVDMTNENAREYVWDRIDKNYKQLGID
                     YYWLDVAEPGYSVYDFDNYRYKKGNVLSCGNIYPIDYLKMIYDGLHNDIESVVTLVRG
                     AWAGAQKYGALVWSGDIDSSFEAFNNQVNTGLNMGLAGIPWWTTDIGGFHGGNPKDPE
                     FRELMVRWFQYATFSPILRMHGDRLPHSKPLSNKGGGSMVTGAPNEIWSYGEEVEVIL
                     TKFIKIRESLKTYLKKLMKEAHEDGTPVMRTLFYEFPEDDKTWEVDNTYMLGDEILVA
                     PIMNYKDRSRKVYLPKGHTWENIFSGVSYEGGKTYEVECPLEEIPIFLKQDSSYNFKE
                     LKNILGEVKS"
     gene            complement(40099..40620)
                     /locus_tag="OE968_001378"
     CDS             complement(40099..40620)
                     /locus_tag="OE968_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HCP7218665.1"
                     /translation="MKRNREIVVVCHCILNCNSKVEGLSEFKGAQNIAIDLINKGYGI
                     IQLPCPEMIMYGINRWGHVKEQFDNLFFREQCRQMLIPHVRQFDEYLKNDYDIKSIIA
                     IDGSPSCGYNKTCSSKRWFGELSGCNELMDKINDIQMVDGKGIFIEELEKLLKEYNLN
                     IPIVGFDELREDK"
     gene            40786..41352
                     /locus_tag="OE968_001379"
     CDS             40786..41352
                     /locus_tag="OE968_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HCP7218666.1"
                     /translation="MDTKKVTFSSMCIVINIVLGMVISMINIPLLFLDTIGTVLGAVV
                     LGPFWSALIGGCTNLVLGVISGPTNIPFALVNIVLGLIVGYISKKKGFGYKEAIITGV
                     ILSIVCPLIGTPISVLLFGGLSGSGADLLVGFLVQSGQKIFTAAFFPRILSNIVDKPL
                     SCIMVVYFISKMPKGFIKQYSKNTSSSY"
BASE COUNT        13673 a         7243 c         4344 g        16320 t
ORIGIN      
        1 taactacttt tttaacatgc ttaaactatt tataaactat tatatttatg tattaaccta
       61 ataacttttt cactaaaaaa taacaatcta ttcaaagata aactatagta cttcttctac
      121 tttgtttcaa taaaatacta aataaatttc gtacatccac aatttttcag gctacactat
      181 aaatatacaa tctttatctt agttataagt ttaagaatat ttttagtctt attttgtcga
      241 atatcttttt aataaaactt cataattcta agcatatttt tacactgtgt tttcatgtac
      301 aaaaataatg cttacaaata aacaacataa ataaaactta aataagatgg attctattca
      361 acatagtatc catcttattc attcaaaacc taaaaggatt ttttataata ttatatattt
      421 taaaatctaa gtaactcatt atagtatcaa tttcacttaa agcttacaat acacttatta
      481 atcttgtttt atattaaaaa catctacaat aacaatttaa atctttaagt gatatccatc
      541 tcacacctaa aggagtaggc tctccgcact attctgtaat tcttcaatac aatcatcatt
      601 attttttata taatttaatt atatatttta ttttaccaaa accagcatac ataaataata
      661 cttaaaatag attaaataaa ggatactaaa acactttatt gaggtatatg acttgaaata
      721 tatgaactaa cttcattagg agaaatatct aaaatagttg caaattcttc atttaataac
      781 ctttcagctt ctttcattat attatcatct gcttgatgtg tttttttacc aatagatttt
      841 acatactctc tgttattatc tatacttctt actaatttta ttaactcttc acatttacca
      901 cctctgagta tttttttaaa ttgctcactt ctcaattttt cattatctat ccatgatgta
      961 tccatattag gaatatcatt tattaatgaa agcacattaa ttttagaaag taactttctc
     1021 attggtactt tttcattatc tacaggaatt tttattactg tattattaga ataaatagga
     1081 ctcaatacat aatactcttt ttttattcca tttgtaaatc gttcatttgt tatatccatg
     1141 actttgcaga ctcctgtcat accatacatt atataatcat caatcttaaa caaaaacatc
     1201 accatcctta ataaaaaaaa tagttttgac aactaaatcc accttgccaa aactatctgc
     1261 tatatattat attttaacac attttaagac ttaaatgtaa gtaaaactta tattattaaa
     1321 attaaaaaat acattaacca ttgattaatg tattttttag atttttataa caagcatatc
     1381 aaaataaatt aatacagctt atctcctgtg aatacctata aaattggtgc ttggctattc
     1441 attgagtacc catcatttct tacatcattt atttctaata tttcatcatt tgttttaacc
     1501 ttagtaagtt ttttaactgc tccataaggt tcttttaatg aaattttatc tcctcttcca
     1561 gaaataaccc ataaaatttt ataccctcta ggtattactt gtagtttatt ttcaccttta
     1621 ccatcagtaa agtagactaa caaattaatc tttttattat tagcatactc aaagactgga
     1681 gaaaatctag tacctccacc tatcctaatt ctatctttta tatctttttc agttctcact
     1741 ttatatacac gtctaatttc attatcacat tctataattg taatttcatg attatagttt
     1801 ttcactatac taagaacttc tttaatagct tgtttaaact cttcatcact aatacttcca
     1861 cttacatcaa gtgcaactgc tatttctgac ttatgacttc taagttctcc cctcaaatct
     1921 aaacgatttg gttgtcttct atttcttctt gttatagtct tctttttatt attttcaact
     1981 gttcccatta ttctattaag atataaattc catggcaatt cacccttact atttttaagt
     2041 gatgatatca tactttctaa ataagcagga actttacctt tttgagaact gttaataaat
     2101 ttttcagtaa attctctaag ggtattttca tctatctcat tggattcatc ccatatatca
     2161 tgagttcttt cggggctata atcaatttct atatctccat atttatcact atcatcttcc
     2221 tcaccatctt catccacttc catcaaatct aattcagtct gaatcttttc tacataatat
     2281 tcaaaaggtt catatggttc aagttttaag gaatacttta aatttaccca ctctaaggta
     2341 gttgcatatg gtggtaaatt gtttagaaat ttatttacta ctatatccat tgccatatta
     2401 attgctaatg tactatactt tccttttaac tcctttgctc tcatcaaatg catagataat
     2461 atatgatgaa tttcatgttt aattgtagtc tccatttgct ttatgtcaag cgttaaaaag
     2521 attattggat taaaatatat aacatattta gctcccttaa aattcacacc tgtaggacta
     2581 cttatatcaa atcttatttc tcttgacatc tgaaacaaaa aatatccata aaaattatct
     2641 tcttcttcca taagacttaa attcacttta tctacaagac taaaaaactc atacttaaaa
     2701 tcttgtggta tatctatatc aaatttctca ttagcacgat ttgcctttag catagaatga
     2761 gtatttataa tttcacttgc tttattataa agctcttttg cttgtttatc aaaataattt
     2821 tccatacatt atccccttat taaactataa gattcaaaat atgattttac aaactcttca
     2881 ttttctatag cttttttata tacttcaata taactgtttc taatatcctt cataatacct
     2941 atcattaaat ctacaggata catttttaaa aattcaataa atctattaat atagtggttt
     3001 gattcatatt tatcattctt aatatttaat tctaagtctt ttagaatgtt catagctgat
     3061 agataaagtc ttgtatgact ctcatttttt actctttcta caatagactc atcaatagat
     3121 tctcctaaaa aaacatcttc ataggatatt aatggttcag agtttgattc aataaaactt
     3181 ataaattctt ctgcaataac tttacctaca ttacccttta caacatttaa aaatactgct
     3241 ctaggaatag aattattttt ttctttataa actttataaa ttttagatac tctctcataa
     3301 cttctaggag tggctcttac atcatcttca tttattttat gcagatattc tggaaaagtg
     3361 gaaataaact cgataacttt tctttcaata ccctcatcta ttgcccattt tatccattgt
     3421 gtatggtcac tctccatatt taaccaaaca aacctatttt cttgggctgc atccatatct
     3481 accacttgat aatcaaaatc tgaaccatat ttacttgatg gattcattgc tgctaaaatc
     3541 tttacatcat catgcagttt atatccatta atttctctat ttaaaattaa attcataagt
     3601 tcttgctgta ctgtatgctc acaacgattt atctcatcta taaataaaag aactgtctta
     3661 cttttagata tctcttcatc aatttctctt aatttgttat gaacagcata cactgttgtt
     3721 ttcttttcag tcttatatcc attagaatta actcctacat aagattctat agttggaaga
     3781 ccacctattt caccctcttt aagtaagttt ccatcaataa caattaaact ccaatcattt
     3841 tctttggcaa gcttatttgc taaagctgtt tttcctattc cactttcacc tactattaaa
     3901 ggtacttctc cagtggataa tattaagtca acgcttttta atgtgtctat aaaattcatt
     3961 tttctctctc ctacataatc tttaatttct catctacagc tatttttttt gctgtcttac
     4021 ttccatattt ataaataaac ataattttat ctattggtat actttcgcta tttctatcta
     4081 taacactaca attcaaaaaa tctctaatat acttttcctc aacatcttct ttggataata
     4141 cttcttttaa tacactctct aattcatctt tagatacttt tttcagaatg tacttaatca
     4201 ctaaaatatt cacttttaaa aattccaaca ttttattttt atctaaatca gttataaagc
     4261 taatagctgc ttcattattt tttatagcta taagttctgc attataacta ggtgaatcta
     4321 tatatctcaa ggcatcataa cttattctca ctgcctcctc ttgtacactt tcataaggtt
     4381 gttttataaa ctttatcgaa tcataatttt ttcttactgc taacagttgt aattcttcac
     4441 ttggattttt agcatattta attgcccatc ctgcttgatt tatagccatt tcaataactt
     4501 tatcagttgg gtttttgata taatccagta tactccatcc ctcatttact gcttttatca
     4561 tcatatcttc tgttggatta tctataaatt taattgctct aatattatta tctattgcta
     4621 gttcttgcat ctctctggtt ggattattta tatattctag tacaagccca ttttctttaa
     4681 tagctaacaa tttcatttca tcagttggat tatctattgt agctataata ttgggattat
     4741 tttttatcat ttcaataact ctcaattttt ccataatgtg cctttctttc tataattatt
     4801 tttatatcta tattaattat aataatctat tcctatttat ataattgttt cttattataa
     4861 ttaatatact ttttaatcaa atttaaacag aataattata ccaatatata aaaaaatttc
     4921 taaaaaacaa taaaattaag ttataaacac caatatattt ctattatttc aatacgtata
     4981 caattagatt agaatctaac gctagtaata aaaaattact ttcccaaagt agatataagc
     5041 ctcattttat cgttcaaata atgaaaatat atttgatttc atgcaaaaag agtgcctaat
     5101 gaactaaaaa gttcattttg agacactcat ttttttatat aagtttatat agtttttaat
     5161 cgttcgcatt caaccactca gttaagactt ttatatattt ctcattttct tcaacgaatg
     5221 gcatatgtct tgaatactca aataattccc acttactatt aggtattcta tcatacatag
     5281 tctttgcaat atatggtgaa cataaatcta ttgctccact agttactaga caaggctctt
     5341 ttatttcatg taatctatct gtaaattcat atccagaaag agttcctgta ggagaaaatt
     5401 cattttgtcc ccatcctaca atatatgctt cagaacctga ttttttaggt cttctcaggc
     5461 actctggaga atcttctgtc acttcacctg cacaatacat ttccataaat ctttctaatg
     5521 catcattata ttctttgcta gagtaatctc cagtatttac tgcatcaagt aatgcttttt
     5581 ggtcaacctc actcatatat gatattcttc ttttttgttc tttctcccaa agttttgcag
     5641 aagaaagagt agatgaaagg atgtaagact taataccttt tggtttatat tcaatagcat
     5701 accaaatagc ctgcatacct ccccaagatt gacctaacag atgaatttca tcaagtccta
     5761 gatgttttct tagttcaata agctcctcta tccaagtatc tgcattaaat agctcaggat
     5821 gcccttctac aaatgaattt ccacaaccaa tttggtcata cattattact tgtctaccac
     5881 tttcagctat cttatccaat acctcaaaat agttgtgtgt agaacctgga cctccatgaa
     5941 gtaatactaa tggcttcttc ccttccgtat tttctcctac tatacggtaa tacgttttaa
     6001 aacctttaaa aggcatatat ccttcagtaa ttttcatgtt tatctcctcc aatttgtaat
     6061 tataaacaat aatcaagttc attaacaata ctatttaaaa cctcttatac atatttgatt
     6121 atgtatttta atctttatac ctacttttat aaatagtata acataaaagt taaaaatctc
     6181 tatactaaac caattataaa attatattaa ctatataatt ttatttttta ataatagtat
     6241 atacatattt gattattttc atttgctatt taaaatcaat tttaagtttt cttcttataa
     6301 taaacttcct ctttgtggtc tcatgttagt ctctaaattt aaaattttac aaaaaatttt
     6361 cataaaataa aattatattg attgtatcta aacaaatagg gcaataaaat aattaagtat
     6421 agttacttac ctttcaagca atattagttt tatgttagaa ttttattata ttgatttaca
     6481 ggaggtttgc atttgaataa tattaattca cttaaagtaa taaaattatc tcttggatgt
     6541 tctcttgcta tatttattgc ttggctatta aaattagaat attcaatggt tgctggagtt
     6601 atagtactac ttacagtaaa ggacactaaa agagaaactc ttaaaggctc cattggaaag
     6661 atttatggtt ttcttttatg tactattttt tcatatttat gttttaatat tttaggatat
     6721 aatttgactt cattttcaat atttatattt ataattatac cactttgttt tttgttaaat
     6781 attcaagatg ttattgctat gtgtgtagtc atagcatccc attactacct tcaaggagaa
     6841 acttctatca aatggatttt aaatgaagct ggaatatttg cagtaggaac tggaataggt
     6901 gtcttaataa atatgtatat tccaacaaat atacataaaa tccatgaagt tcaaaaaaag
     6961 ttacaggaag aagtgagtat tgtacttata gacattgcag atattattgt aaatcctaaa
     7021 aaagaaaatg gatatagtag agatttatat acattaaatt cacttattga cagcagtatt
     7081 tctgaaactt acgataatat taataatact ttattaagtg atactagatt cttcttagaa
     7141 catatggata ttataaaaag ccaacgggat atcttagaaa atttgtatag ttatgtatct
     7201 caactaaatt ctacaccacc acaagctcat attctatctg cttttataca taagataggt
     7261 tatactgaat ttgaagctga aacaggcaat cttcttcttg aagaattaaa gagactaatg
     7321 cttagtatga aaaaccagcc tctgcctgtt gacagaacag agtttgaaaa tagagctatt
     7381 ttattcctat gcttgactga gttaaaacag tttttagtta atcgtaaaca tgctcagata
     7441 cttagagata ataattttta taaataaaaa ggggagaaat ctagcagttg acctgactac
     7501 aaaatatcag atataatatt aaatgcgccc ctagtaagag ggcgcaatgt ttataactta
     7561 ttctactgtc atgattaaat cattattcat atcgaacata cattatttga ccaagtccaa
     7621 tattagcttt ttcatcagtg atttctattt taatagtcac atcatttttt ttacagtact
     7681 tcgctaattc tgcaccagaa cgatttttac cactaaaatc taaagaaaat ggcttatcat
     7741 atttaaaagg atattcaaca ggtttaccct ctggtgctaa tgcaaacatc ccatatggtg
     7801 tgttcataaa tcctattaca gcaatcgtaa gatttgatgg gtctaaattt gattcactac
     7861 ctgtaaatgt aattgtattt actgatgaat taactacact acatctaaca ccttcataca
     7921 ttacatgttt ttcatttata tcttctcctt tttttccaaa atttccaaca gcctttgccc
     7981 cttcttgatg tggtaacata gtgtgctttc caggtggtgc tggtttctgt gtctgttctg
     8041 gttttaccgt ctgtactatt gcaccaactt ttggatatgc tgtcttatca aatggtaatg
     8101 ggtggctaag actcttgtat atgatatcct ttcctgctga tttattagca tcaatatcta
     8161 catgatacaa acgcccatca ccaaaacgga taagattcca ctggtggtca tttgatgtgc
     8221 tgtgtacata ataagattca attcccatag catcacacaa agctttcatg ctcctagcca
     8281 ttcctgagca tgcacctttt ttagtaacca atgtataggc agtatttgct ccctctactg
     8341 cattccagtc aacatatgtt gtgttatttt taatgtgatt gtaggcaact aaaatcttag
     8401 catctgtggt catattcttt gtgattttct tgttcataaa atctgctgtt gcttgtgcta
     8461 ctgagtttag ttgggcttgt gacagctttg gaccatatac gctattggtt ccagtgacat
     8521 agctttttgg tgtttttgct gttacctctt tggctgtcat accataaact gtcatactca
     8581 tacctgagat taaaactatt gttgtaatca ataacttggt agttaacttc ctaattttct
     8641 tcatacttaa tattctcctt tataaaacat tgttacttcc tattctctac cattaataaa
     8701 attaatttag tatttaaaaa ggtggattgt caacatgtat atttctccat tcatacattc
     8761 gtgaaatatt taaattttat ggaaaatcta atagatattt tctagataat ttgtatacaa
     8821 tacaactcgc aaatcagggt atttgctgtt agtttgagaa aatgatgatg attaatacat
     8881 tcggaatctt tgacctataa taaataccat tgtcttcaat cattaataat ggtaagagta
     8941 aagagaatta tcaataatac agttaaaatc aactttgtat acatttcata cattctctcc
     9001 caacaacatt atacttctta taatttgtat attcaatacg ttttctggga aaatatagga
     9061 tatatctata aaaatataaa aaaggagttg aacttaaaat ttgattaaaa aaaatcaatt
     9121 ttaagacaac tcatttgtat tataaaaatg ctatatatta ttattaagta agtcaatatt
     9181 ttagatattt atctatttct tattgactta cgcttatagc ctaacttatt tgtttagttg
     9241 atatataacc tagttttaag cattattaat atttaaataa tcaagtatcc tttttgtttc
     9301 ttgtagtttc tgttctgcct catttaagtt ttcttgaatt atagaaatat atattatatc
     9361 tatcaacgta agcattgcta ttcttgaaga aatagctcct tctctaagtc ttttttctat
     9421 atttggtact actagcttta aatcactaat cttactaaga tgattgtcac tatatttagt
     9481 tatacaaatg accttacatc cttttaattt tgcattttct atagacttta ttacttcttt
     9541 tgattctcca gagtaagata ttgctatagc tatatcttct ttatctacat ttgaagatac
     9601 cataagttgt gtatgactat ctaaagaggt aaatgcctgt ttatttatcc ttaaaagttt
     9661 catctgtaaa tctagtgcaa ctaaagccga accacctact ccaaatatat atacattttt
     9721 agcctttatt atctgttcaa ctgcttcttt tattatatct ttttcattca acaaccttgt
     9781 ttggttgata gtctctatgt ttttgtttgt aattttgttt ataacactat ctatattaca
     9841 atcatagttt tcatctacat atgtgtattc attttctttg cccatcaaat ctttagctat
     9901 ctcaattttt aaatccccaa aacccgaata tcccattttt ctagaaaacc taactatact
     9961 tgctgtactt gtttttgagt ttgacgccaa ttctgataca gaaagcttac ttatagcctc
    10021 tgtattatta agtatgtaat cagctatttt tttatctact tccgttaaat cttcatatat
    10081 ctgttttaat tttaaaatgc aactcatact ctatcacctc tacctattta ctataatatt
    10141 tcttcttagc aagtaaacat gctcctaaat ctggagtcaa cactggtctc actataccaa
    10201 atctcgtttt attcaaatat tttttaagtg gctctaatat taaatctcct gacttaaaca
    10261 ctccacctga ataagatacc tttatctttg taccttgttc aaaatgatgc tctaatccta
    10321 ttataagcct acttaattca taagctgcat catcaaatat tttactagca gtattatcac
    10381 cttcaataac tgcttttaaa catatcgtag caaactttgc tatttctatt ctatctcctt
    10441 gtatttcatc atttacatat tttattatgt cataatcatt ctctatatta agatgtcttt
    10501 ttattaaatc atataatttt gtttttgaac accttccatc agactgcatt gtgaacattt
    10561 ttaaggtagc cattcctata taatacgctg aaccttcatc tcctaataca tagccccatc
    10621 ctccacatct gtgaagattc ccatctttat ctaaagcctg tgctattgaa ccagtacctg
    10681 caattatatt tatacctttt tccccattta aagaacctgc taatgctatt tctacatcat
    10741 tacctagagt ataatttata tgactatatg cattttttgt tgctacttct aatgcataca
    10801 atacttcttt tatttttcca tatccagcaa gtccaacaaa tgcatacgtt atttcttcta
    10861 catttatctt agcatcttta caaacttctt ccaacccagt tattaataat ttcgttagat
    10921 tatcaaatcc tatttgatta taatgacaag ttcctttggt tatggttcct actatattta
    10981 attcttcatc tactaatgta aatgttgttt tcgttcctcc accatctaca cctaaaaaat
    11041 acatactatc ctcctacaat atctttaata attctttcaa tacttaatat ctaaaaataa
    11101 ccttccaatg ctgttttttt aatattgaaa ggttatcagt actattattt attttacaat
    11161 ttttctattg attttaaagc ttcacttata taaccttctt gtctatctag gatactcttt
    11221 gcactatcct tatctaaacc actttttatc ataaatatag ccaatttaac gctattatct
    11281 gcttcttcta agaatttttc tgcaacatca tattttacat ttgtagctat cattattatt
    11341 ctttttgctc tttcaaccaa cttttcattt gatgtcttaa catctaccat caagtttgag
    11401 tatacttttc ccatcttaac catagaagct gttgttaaca tattacatac cattttttga
    11461 gctgtaccac ttttcattct agttgaaccc attattactt ctgcccctac tataatgttt
    11521 attggtaaat ccgctttttt actcatttca ctattcggat tcatagttat tgatagtact
    11581 gcacacccca attccttagc atactccatt gcacctataa cataaggagt ccttcctgat
    11641 gcagctatac cacatataac atccttagat gtaactcctc tatctattat atcttgcttt
    11701 ccaagttctt tatcatcttc agcaccttct attgctttaa atattgcttg atttccacca
    11761 gctattatag cttgaacaag ctcaaaatcc actccgtaag ttggaggaca ttctgtggca
    11821 tctagtattc ctatcctacc actggtgcct gctcctatat agaataatct acctccctgc
    11881 ttcattctat ctactattat attaacagct tttgctatac tctccttttg ttcttcaaca
    11941 gcataggcta cagttttatc ttcgttattt attaattcta ttatgcctaa tgtatcttct
    12001 ttatctattt gcaatgtatt cttatttcta ccttctgtaa ctaaattttc taaagttttt
    12061 attaacatat catttcctca ttttcttaat attaaatttt taaacacatt ttaattccaa
    12121 ctttcataat tatattttta taataaatta atattttcat aataaattat tttgttgagg
    12181 gtttaaaatt aaacttttgc catggtttaa tataatctaa tataaataat tcttcttttc
    12241 ttatatatcc tactacattc gatttaccac tgtttttcat atcagtcaag gctatttgta
    12301 actcccctgc ataatgacca tattcactac tttcaattac tatatctcct ctttttatta
    12361 ttttaggagt attaaatagt tcaaatttgt atcctttata tttaacacga gattgagtag
    12421 accttatcag actgtcagat atgtcccctc tattaaaatg tatttcttca aagagtatct
    12481 tcttctcaac ttctcgtata ttttcctcta ttgctacatc aaatgtaacc atatcttttc
    12541 tcatagaacc taataccttt agctcctcat atgttggata acaatttgat attattatat
    12601 catttatatt attcatagct attatatgct ttacttgaat atctataggt agatttctgt
    12661 gcatctcaat tgttggaagc ccatcagtta caggccatgg tccaaatgta gtttcatttt
    12721 gacttgttac aaaaactgct gttcttaatc catacttatt aaatctttct gtacatttta
    12781 taaagtgttc taaatttaat ccactatatc tatgtggata aaagttatga catcctgtca
    12841 agttttcttt atttggttgg tagtccatta ttgtatctat ataattagta ttattactca
    12901 tattgatttc tattttaaga ttttgaggat taaaagtcat taatgcctct tcagaacctg
    12961 taaatcctat atcaagcctt attccgtctg ccttcgtctt tttaaaaaaa gtcaaatctt
    13021 tgtagcttat ttctaattca ccaaatactc tgggatttac atcaagtatt acctcaaaac
    13081 ctttaaactt agcgtattca tttatacgtt taaatttttt aattatattt tctttagtat
    13141 ctttaactga taataaacat gaaaatatac gtgtaaatcc attttcagca gctttatcta
    13201 tataatcata tatttcctta gatgttgttt tttctggata aattgatatt cctaatcttc
    13261 ccatctgtgt catctcctta tatcctatat gtgtttaaat ttatttcgaa ttacacgaaa
    13321 cttttttaaa aatttggtga aaaaaagttt catatatatt tataaaaaaa gaaaagttta
    13381 ccttttcttt ttttataaac aatcaacaaa atatcttcgt tacttatttc ataactgtta
    13441 tactttgaaa tttatactaa tctaatatag tttttaattt ccaatatagt ttctaattaa
    13501 taagcttctt gctcttcaac tttttcttca tgaagcaatc tcttatcgta catcttgaca
    13561 aatggatagt aaattattat tgatatagct atacataata agttaagaac tgaagctctc
    13621 caatctccac cagtggctaa atatgcccct actggtcctg gtaatgtcca aggagcagta
    13681 actactactc tggatactaa attagcactc atagcaaacc atgaaactgt tgccattact
    13741 attggtgcta caacaaatgg tattattaat attgggttta atactattgg tgctccaaat
    13801 attattggtt catttatatt gaatattgct ggtattacag ttgcttttcc taaagacttt
    13861 ccataagctg attttgctct aaatgcaaga agtaaagcta agcctattgt agctccagaa
    13921 cctccaatcc atataaacca ttgaaaaaag ggttcagcag caatacctgg aactgcttga
    13981 cccgcagcat atgaagctgt attagcatct aataattgta tccataaagg tcttgccaat
    14041 gaacctatta ttgatacacc atgtattcca aatgaccaaa aaaacgttat taaaaatatt
    14101 agtataatta ctgatggtaa tgtgtcagtg gctgaaacta atggagttac taatttagct
    14161 atgaagccat gccaatcaaa ccctaggaaa taagtaacaa tagccattaa aattattatt
    14221 aatgcggctg gtgtcagagc ttcaaaagac cttgtgactg atgctggaac tgcttctggc
    14281 atggttatct tgaatttaga tttgtcagta aatctataaa tctcaacacc tattatagat
    14341 gttacaatag caacaaacat tgaacctcca ccaagattag ccattggcat ttgccatcct
    14401 tgaggaattg aattatacca agctaaaagt tctggactct tttcaactat ctttaataac
    14461 tcaggggtaa gaccctctat tgcagtagga actattgtca aaaggaatgt agctgtagct
    14521 aataaacctc ctgtcaatcc atctaactta tatgactttg ccaaactata acctatgcca
    14581 aatgtagaat atactgatat aataaaaaat gtcattctat atggtagtaa tattgtaact
    14641 gcattttcct ttagatactg agttaccccc catgaatctg gtaatggagg aaatgctaat
    14701 atcaagaaaa atgacccaac tattataagt ggtaatgaag ctacgattcc atctcttaca
    14761 gctcttaagt gacgttgttc tgccaatctg gccatagaag ttgataattt agtgtctaaa
    14821 aattctgtaa atttatctag catcttttct ctccttaatt aatatttatt tttattatca
    14881 ttaaaatttt tataaaatca actttcttct aatctaacaa cactgcaact actatttact
    14941 caacagttct tgaacttgtt ttaataactt tggtcctcct aatggactat aagcttgtgc
    15001 ttgtattaat gcacatggta cactaacctc atcagcaaaa gcttttaaat agtcaaatct
    15061 atgtctgact tgtggagcta ccatagcaat atcccatcca tttttaactt cattctcaaa
    15121 ctcttgagta ccaacagcca aaacatctat atctattcca ttttttgctc cttctttttg
    15181 taatgcatta actgctatag cacttgacat ccctgatgaa caaacaaata atactctcat
    15241 attgattccc cctgtttttt tatttctttt caatcattat agcatgtatt tttgattaca
    15301 ggaatacgtt tgtatatatt ttttcatatt ttacatttta aattgtaatt ttatttcatg
    15361 catttatatc ttgctttaat tgctttattt atctaatcat tcttttgtct aaaattacac
    15421 actacttaaa atactcatat cttttcttaa aaaagaaaaa agactatctt attattaaca
    15481 taaaatagtc tcaatacttt tttaaatatg tattccttta tatatccaga agtaacctat
    15541 tattgcaaat gataaagcaa ataaaatata cagtctaaaa aatcccaaag aaaaacctct
    15601 cttagtttca acaaagtatc ttgtatatgc aactgcaaaa gatgtaatta atgaatttcc
    15661 tataacaact ccaaatctat tatctattcc aaatatagat aataacaaag gaaaaactac
    15721 agtacttaca agagatgaaa ctattagtat taatccactt ttaaaactta tagttggaat
    15781 attataatct gttctttgat ttttctccat ttgtttctta gtatttttat tactttttgt
    15841 actttttgca tttttataat tattattttt ctttcttttc ttttttttat tattagacat
    15901 gtcatttacc tccaaaaggt ttaggtgtta tattccctaa aataacttta tttttagccc
    15961 ctgttgcaga tattacatta gaaaaagaat tatttaatgt ttcattgccc aagattacaa
    16021 atgccaaagc ctcctttgca tcagaagaat acccatattc atcttgagtt aatacttcaa
    16081 cctctaataa taactctttt atatatccta ttaaagttag attatgagct cctccacctc
    16141 caattaataa agtatctaca ttaacctttg gaagtatgaa gtttttataa ttataatata
    16201 tagcttttgc cgtaaacata gttactgttg ctatcaaatc atatttatct acatgtttat
    16261 atttgttaag catgttatcc aaataaactt gtccaaatac ctctcttcca gtgcttttag
    16321 gtggcgcttg actaagatac ttatgactca tcaaatcttt taacatttct tcattaattt
    16381 taccttttga tgcaaagtat ccatttttat catactttct attaaataat ctttgacata
    16441 ctccatctat tatcatattt cctggtcctg tatcaaatgc aaatacatca tctatgttac
    16501 atgatttagg tattatagta atatttccta ttccaccaat attttgaagt gctaaatttt
    16561 tattgttatc actatataat aaaaattcac tatatggtac taatggagca ccttctccac
    16621 ctgctgctat atccattact ctaaaattag atattacctt tgtatttgtt tcatatgcta
    16681 taactgctgg ttcacctatt tgaagcgttg aagatacaaa attattataa cttcttggta
    16741 tatgaaagat tgtttgacca tgagatgcga taaaatccaa atttgctata tgaaagtttg
    16801 ctttatgaca cactgatttt acagctttac taaataaata tccaagctta aaatttaagc
    16861 tacagattaa atcaacactc gattcctctt ctatacagca ctttcttatt tcgtctttta
    16921 tatctttagg aatttctaga gttataaatt ctatttgctt aactttagta tttctaccat
    16981 tcccactaat ttcagctagt actgcatcaa ctccatctaa ggaagttcct gacattaaac
    17041 ctacactata catagttatc atccttttaa gtttatagtt attcctcccc aaatcaaggt
    17101 attaagttta ataattttag aattaatctt atttcatctt taattacgat aatttactct
    17161 tacgaaatta atcgagttaa tcttatacac gttttttacc ttagctaaat cttacattaa
    17221 tttattttca gtgtcaatgt aataccatgt aatttttttt cacaaacaaa acatattctc
    17281 tctccaaaaa ccatattaaa atagttacta caaataaaaa acataccagg tacctatctg
    17341 atatgttttt catatataat aattattatt ttataatata gatggagcat catttaaggc
    17401 actaattaaa tcttcactat tttcaagaac taaatttatt cttattgtat atgtcgattt
    17461 gtatatgatg atagatttta tagtctaata acctaactat ctatgcttaa ataatccgat
    17521 atatcataaa agtagatatt aaaaattgta tatgaaccaa ttttcgaaca tacctcaatc
    17581 tcatgcccta aactatctat cattttcttt acaaaataca tccccattcc agtagactta
    17641 tacaattgat ttcttccatt tttccccgta aatcccttgt caaaaaccct agatatatct
    17701 tcctcattta tacctatacc aaaatctttt atagataata ccactccatt ttctaacttt
    17761 tttgaattaa attcaatctt accaacttcc tttgaatact ttatagcatt attaataatt
    17821 tggtctaaaa catatgacat gcatttagaa tctgtgtaaa catcattttc taattcattc
    17881 aaactaactt ctacattatt ttttataagc aaaaatgaat tattttttat agacattttt
    17941 accaattttt ctaaattaaa tttatttata aatacatctt caaacatagt gttgcttcta
    18001 ctactataca aaatagagtt tactaaaaaa tttatctttg caacctgatt cttaatatcc
    18061 aaactatctt ctatgctact taacctatct gtaattatac ttaaagaaga tattggaatt
    18121 tttatttcat gaacccattt agctatgtac tcatccaatt cttttaatga ttgtttataa
    18181 gtctctatgt cactattatt ttttattttt aagttttcta taatatcttt tattagattt
    18241 tcttcaaaag attgtccatc aactaaataa ctatctattt caccactatt ttctatacaa
    18301 ttatataaat ttgtgtaact atttctaaaa tttatataat ctataacaaa aaataccatt
    18361 attataaaca gcactaaaaa atctaaatat attaactctg aatatttatt tttaaaaata
    18421 tctatagcaa ataagtagat atttattata ctaactacaa ctaaaggtag agcaatatac
    18481 ttagacctac ctttcaaata ttttactagc attgtattat atatcctatc cccttcttag
    18541 tttttataaa atcatcaaaa cccagttctt taactttact tctcaatcta ttcatattta
    18601 cagtaagtgc attgtatgtc acaaactcgt cattatccca tagagtcatc ataagacttt
    18661 cccttgatac aaccctattc ttatttttta ataataatgt taaaattttt atttcgtttt
    18721 tagtcaactc tatactttta tccttatact tatgttttat aatccctttc cccacatcaa
    18781 acatcaaatc ttcacaatac aaaatactat tagaatcact ataattatag actcttctta
    18841 ttataccatt tattttggta accaatattt ctatagaaaa tggtttggta atgtaatcat
    18901 ctgctccatt atttatgccc attattaaat ccatatcaga atctcttgat gataaaaata
    18961 ttaatggtac atttgaaata gctcttattt tttcgcacca gtaaaatcca ttatataatg
    19021 gtaaatttac atctaaaagt actacatctg gttttttatc tataaattca tctaatacta
    19081 cctcaaaatc atcaattaat tctactttaa atccccattt ttcaagtgct aacgcaatct
    19141 cttttgataa atcaatatcg tcctctacta ataaaattct atacatttgt atattctcca
    19201 ttatcctaat atttcactat gctatgaatt attaatatca taacatattt tatatgaatt
    19261 tattacccaa attatttagt taatcaacaa ggagactctt attacaagaa tctcctttct
    19321 ctttattaat atatcaacta atttttatac actacactct taaacttatt aacagatact
    19381 gctccatata ttatgaatat tatcaaacat atcactaaac ttagtatata tataccaaat
    19441 aaatcggtca tcaataaatc tcctgctaat ctcaatgcaa aataactaga tatagttgca
    19501 cttaacattg gcaaagtata aaaaatagct acttctttaa gtatagctct atttatatct
    19561 ttttctgtag tacctatttt taacaaaatc ttatatttct ctttatcttc atatgcatca
    19621 ctatatattt tcatatatat tatacttcca gctacaattg caaagactaa gaataaaaac
    19681 acaagcacta catatgcaaa cttcatccat tgactctcac cttgagcttt atatccattt
    19741 tgaatatacc cattttttaa acttaaattc ttttcaatat tgttgaacat tacttgacta
    19801 ttttcttctt gaaatacctt tgcaccataa aaatacactt gttgaccctt atctcttagt
    19861 ttaaaatatg tatcatcatt taccactata atactttgat taagtcctgt ccctagtact
    19921 ggaactttta cttctcccct tgaaatatta tataactgac catcaagttt tatcttggct
    19981 tcttttgtag ctattgatgc tatcgtttga gggcttttta actctattac attatttcca
    20041 ctaactaatc tttcaccata ctcttttaat tctttatcat taccattcac tttaagagta
    20101 ttacaaaaat cactatattt cattatagta tctgttgtat cataagcttc ttttatatct
    20161 gttttcttta aaattgttag ttctggattt actgagtact ttatcttatt agtatctttt
    20221 attatattct ctatttgttt tttattcact tcatctttat ccattgaaac tatgctaata
    20281 gtgtacacat ttctttgttc ttgggcattc ttatgtatat gcttcatagc aactgaagca
    20341 ccaagagttg atattgttgt agttataatt atagctatta tagcataagt tttatagttt
    20401 ttatttaatc ggtagtttat attgtttatt gcaattatat tatttccatt aaataatatt
    20461 tttttatttt tgattataat atcaaatata acaggcataa ctgatttgaa taatccataa
    20521 gtacctacta ttattatacc tataacaggt agtacactag ttatatctcc agttcttata
    20581 ttggtagaaa gatagtagcc atatcctatt actataattg atactatagc taatatatat
    20641 atacctattc ctacctttgg tattttttct tgttttttag atatattgat tagatttatt
    20701 acactacttc tacatattgt tataaaacct tttacagcca ttattataaa tatagaaata
    20761 aagattaaag tagcatatag tatagcttct atactaagtc cattagatac ctttatatta
    20821 aatccagata actttattat cactacttga aaaaatctag atgttattat ccctataatt
    20881 attcctgtta tacaagaact tattcctata agcatatttt ctacaaaata tatttttcct
    20941 atagtatata aatctaatcc cataaaagac aatattccaa tttctttaga cctattctta
    21001 aaaaatatat ttgttgcata ccatataaag aaaaataaaa atactgatag tatcattatt
    21061 acagctacta acactgatag tgtaaatttt ttattttcct cttgtaacac atttatagca
    21121 tcaccatatc ttaataattc aaaattagtt agcacaacta ctgaaaaaac catagatata
    21181 aaaaatgcta gataagttct tatgttactc ttaaaattat tataagcaat tccaagtata
    21241 ctcacttaca tctcacctcc catagaggct agcatatcca taatttttcc ataaaattct
    21301 tttctactat ttcctttgtt taatttacac tttatatttc catcatttat catatatact
    21361 tcatttgaat aacttgctgt tagagggtca tgtgtaatca ttataatagt agcgttattt
    21421 tctctgttta ttttttctaa tgattctaaa agttcatatg ctgatttaga gtctaaagca
    21481 ccagttggct catcagcaaa tatgactgtt ggatttgtaa ttaatgacct agctgctgcg
    21541 cctctttgtt tttgtcctcc tgataactga tatggatatt tatctaaatg attttctaat
    21601 ccaaattttt tagctataga aaatacctta gcttctatct ccttactttt cttttttcct
    21661 aatgctagag gaagtgctat attgtccatt agtttcatat tgtctaatag attatagtct
    21721 tgaaatataa accctatttt ttctcttctt aattttgata gttcattatt ttttactttt
    21781 gatatattaa ttccatctag tattatttct cctgaagttt gtttgtcaag tgtagacatt
    21841 aaatttagca atgttgtctt tcctgcacca gatggaccca ttattgatat aaaatcacct
    21901 tcattgactg taagagatat attttttaat acatttgttt taaatccttt tattccataa
    21961 tcttttgata tattttttat ttttaatatt tctttcataa caatagcctc cagttgctaa
    22021 ttttttaata tatatttatt ttaaaggttt tatataaata aatccttaag taaatattac
    22081 attttaactg ttagcattac acttttgtaa catatggaag actattataa ttatagtaga
    22141 aatatcttaa aataaaagca tgatttactt ctttgtataa acaaagaaaa gaagctccta
    22201 agaagcctct aatctataca attattcttc tctataaaaa accaaaatac acattgattg
    22261 tggcaaatac agatactata aacaagtgat attactacta tatattaaaa caattattcc
    22321 tgaagataat tcaataagac tatcaagcaa taagctaagc atccaaaaag acttaatacc
    22381 attaatgtat aattataccc aatattaatg cttaaaaaac cagcaacagt tggaataatc
    22441 agagatgaac ctcccataaa tatacttaaa gctattaatt ggctactact tctaagtttt
    22501 ttaggagaaa cttcaaatat taatcttttt gaagtaatta aaattaaagg agtagaaaac
    22561 acttgaaaaa cacacagtat aataatgata tttgaatcat ttgttaaagc aaataataga
    22621 aactgaactg ttatcataat agcacttaat tttaataagt ttaaactgct atattttttt
    22681 aataaataag aaccagccag atatgttggt atctctaaca atgactgtaa agaccacttt
    22741 aaagatatct gagaatttgt agcatttaaa gctatcattt tatctattac agtacagtta
    22801 tttgctacca ccattgagta taataagaat aaaatacata ctagtaagat atatttttta
    22861 tcttttaata attcaataat atctttatta gttacattta ttttcttatt aatcttttca
    22921 atatcaggta ataatagtat atttataata agtaatacta caattaaacc aatcgctaca
    22981 gataatccaa aatatgagaa tctaagaatc aagtaagatg ctaccatact tccaatagcc
    23041 catccaatcg acccaaaagt cttaataaat gacaaataat tattaatatt atctccacaa
    23101 cctattatcc atgtatcata taaactacag caagtattta ataatcctcc tgataaagca
    23161 acaagtaata agtatattat aaaagttgca gattcagtag aaaacataat aactgatgca
    23221 attccataaa ctgataaact aattaaaaca atttttttca ttgtttgata cttatcagct
    23281 aatactccaa ataataattg aaataatata ttggttattg cataactcga taatataatt
    23341 cctctttcaa acgctgagta acctaatttt gataagaaag gtgtgaattt tgttgaagca
    23401 aaggcaaaaa taatatatga gaaaaaatag aatatgataa atttaaattt aatcgcttta
    23461 ttaatcataa tcaatcaaaa ttgataactt taataccact atttccttcc tgatttaagt
    23521 ttgaaagatg atattttacc gtattaggat tctctacaat aactaaagga atatataaag
    23581 tattttcaag taacttatta tcaatttcta ctaacttttc ccccatatta acttcttgac
    23641 cttgtttaac ttctaattta aagttttctt tttttgttgt tgcactgtcc aatccaatat
    23701 gaataagaat ttgaacatca ttttgcaatt taattcctat agcatggtta gtttgagcaa
    23761 taaaacttat tactccttta gtcggtgatt taagaatatt gtcctttgct atcatagcaa
    23821 atccatctcc cattacctta gttgaaaata ctttatcagg aatttctcca agattaatta
    23881 tttttccatc aatgtatgaa ttaattgtaa ttgcttcttt ttttctttta aagaacatta
    23941 tagacactcc tctacataat taactttatt ctaattatca ttacaaataa cgatattaag
    24001 catactgcaa ttgaggaaaa aagagcctta tagctctttc cccattgtag ttctttaata
    24061 ctgcttatga tttgtttaat tccaacaaat ttataaatat aggtaaacat gataacaata
    24121 gttattgtgt aaatttggaa tatctgccct aataagacta aatagaaagc aatcatgttt
    24181 tcttttatct ctttattctt ttttatattg taaataacat atgcactgta tactgcacta
    24241 aagttagaga ttaaatttaa acttgcatta acatcattgt ttaaaagttg tgaaaatgaa
    24301 atatttgtaa ataatgatgt caattctaaa tacactatat ataaaacagg taatattaga
    24361 aaacaaacca taaccactga aagaaatata ttttcatctt ttaatactgc tgtgatattt
    24421 tttattttat ttgttatcat gtttttgttc tccttattta aaagttggcc agaaatcctt
    24481 attagccaca atcatttcat ctaagatttc ttttgctact tttgcacttg gaacagtttt
    24541 actcatagta aacgactgcc ataatttttg ataacttttt tctatccatg cttctacagc
    24601 taatttttca gaagcaactt gttgttccat taaacctttt tggaaagttg gaattttacc
    24661 tatagacata ggttcaacca tatcttttcc aacaaggcaa ggaatttcaa ccattgcatc
    24721 atctgcaaaa ttttcaatag ctccattatt aggaacaatc agtaaaaatc tttcctgagt
    24781 attaaatgct aatgcacaag ctaattcaac aataaattga gaatgctcac ttgcatcaaa
    24841 ccatgtatcc cttgctgtgc cattttttat aattctttca cattcttcga atgtatcctt
    24901 ttctcttcta tccataattt catttgctct tgtataattt ggattagcat gttcaacagt
    24961 ttcatcagcc attaaataat attttaaata agtattaggt aatgtagttg gttctatttc
    25021 taataagtcc tttgctgctc tcatagtttc taaccaacta gattctttgt gttgaccttg
    25081 aggtgtaaat tcctcatatc cttttttagc acaatattct tgtaatttag gcattaaatc
    25141 atttccttct ttgtccttaa tacttgtcca ccacccgaaa tgattcaatc cataatatct
    25201 aacatcaaag tctttacgag aatttaaacc taaaactcta gcaaatattt cctctaaaca
    25261 tactggcata tcacaaatat taataattct tgaatttggt cttaatacac gacatgcttc
    25321 tgcaactata gctgctggat ttgaataatt aagcatccaa gcatttggag aatatttttc
    25381 catataatca atcatttcga ttattggacc tattgttctt aatccatagg caattccacc
    25441 tgccccacaa gtttcttgac caacaacccc atattttagt ggaatttttt catcttgttc
    25501 acgtaaagca tataaaccaa cacgaatttg tgccattaca aaatcaatat cagtaaatgc
    25561 ttcttctgga tttgttgtat aactaaattt aatttctgga tttttctctc taacaattat
    25621 tgcacatgct tcagcaactt ttctttgtct ctcatcatta ttatcatata atttaattga
    25681 ttcaatagga aatttagcaa cactttcaat taacattgtt acaattccag cagtataagt
    25741 actaccccca ccagcaatta gtatcctctg tctttttctt tccatctttc cttctccttt
    25801 ataataaatt ttcaaattct tctcttacac ttggtactga aagcccaata ataatctgaa
    25861 tagcttttcc attatgcact aaaccatgtg cacctactgc cttaaaatct tcttctttag
    25921 aaataattga gtcatctttc aaggttaatc tcaacctcgt agcacagttt gtaacatcta
    25981 caacattttc tgctccacca actaatttta tgtattcaga tgcttgttga gaggctttac
    26041 tcaatttatt tcctttttca tctttagttt ctaagtattc atttttagta tatagttttg
    26101 tttcttcact atcttcttct ctaccaggag ttttcatatc aaacttctta attaagaaag
    26161 taaatacaaa gaaccagata aatgaaaata taatccctac aacaacttga acaacatata
    26221 ccttccagtg atacattcca agaggaagcc aatttaatac aacccagtta ataattcctc
    26281 caccaaaatc accaacaact cctaaggcaa acgaaatcgt ttgcaagcac gcatctaaaa
    26341 atgcatgtac taggaataaa agtggtgcta caaataaaaa tgtaaattct aacggctcag
    26401 taattccagt taatactgca gtaagagtag caggaatcat taaacctaat acttttttct
    26461 ttttttctgg ctttgcagtt acatagaaag caccaaatac acctaatgaa ccaaacacct
    26521 tcgataatcc ggataatgaa aatccgattg gatacatttc ctttagagtc ttagctgaag
    26581 tttgaaaatc ctgaatatga gtagcccaat atactgatgt accacctgga acaacaacac
    26641 tatcataaca aattggtgca tatacaaaat gatgtaatcc agttggtatt aaaatctttt
    26701 gtaagaatgc ataacaccaa actcctatat ttccactatt tataaaaaac gtttgcaaat
    26761 gtctaataac attttgaata tgaggccaaa taaaacaagt taataatgca actggtatca
    26821 taacaaagaa acaaattgca actacaagtg atgagcctct aaataatcca ataaaatctg
    26881 gtagttcttt atcataaaat ctattatgaa tataaatgac aatacctgat attaacaaag
    26941 caccaaccat accagtatct aatgttttaa taccagcaat gcttacaagt ccacttccag
    27001 cacttatttc agctgcgaaa tcaactccaa agctttttcc ccaaaaactt aacatagaac
    27061 ctacaaaata attaaaagtc aaatacgttg ctaaagcctc catacaagct cttgcttgtt
    27121 gcttttttgc aagtgctatt ggtaaagaaa tagcaaataa taatggtaat tgattaaata
    27181 ccatccaagc tccactagat attacacccc aaaattggta ccaaatattt tctggtgtag
    27241 caagtgaacc cataattgac tgattttgaa atacaattga gaatccaacc attatcccag
    27301 caaaagcaaa taatagtgtt ggtgtaaaca ttgcccctcc aaaacgctgt attttcttca
    27361 tcatataaat tactcccctc ctcatatttt tagtttatct ttggccttag atatctatta
    27421 ttttaacagg ttaataaata tatacaatct ttagggtaca tttggagctt attcacagtc
    27481 aaataagttt ttgcacattt ttatgttcaa attctcataa aaaaaaagaa tgactacaat
    27541 ttgcaatcaa tcccttctgt aatcattcta tgccttttat aaatactata tttaataaat
    27601 aataactcaa tcaatataaa atataacatt gtcaatttat aactagggtg catttgtaaa
    27661 aatgagatat tagtcgctga aatataaatt gattcatcac ttaaatcagt caatgtatta
    27721 tttttaaact ctgtaattga aattatttta gttcctatta attttaatct tctagcaata
    27781 ttaagtgtat tctcattctc accacttagg gatataataa tcataacatc atttttactg
    27841 acaatattgt aaaaagaatc atcaaatgtt cttccctcaa aatcatatat tatttcttga
    27901 catgataaga acattctctt tatctgtttt gcaactacat tttgaatatc acctgaacca
    27961 taagcgtata ttgttcttga ttcataaaga agtttacaca atgcatcata atctttattt
    28021 ttttgatctt caacatactt aattattgaa ttacatgcaa tatcaaatga ctgattttct
    28081 atgacatgaa ccttttctga ttcccagctt aataatactt taaactcact gaaacctttt
    28141 aaatctaatt ttttaacaaa tcttgtaata gttgcacgag acacattaca tttcatagca
    28201 agttcattta ttgacatctt actacaatgt tttttatttg cagttatata tttccatatt
    28261 aataaatctg tatcattcaa tttattataa tttaaaaaaa tcatttcttc taatctcata
    28321 aactattacc ccctttaatt aaaaatcgtc ataaatatta taccaatatt caacattaaa
    28381 ttacagcgta ttcttatatt tactatttag cccataaaat tgactataaa aaatactgct
    28441 ataattgatg tttaaaaaaa tgtagtttta attttattct tttatctaat aattaatatt
    28501 ttcaagttct agtgcttttc ttatacaatt atcatcttta aaatcagcag tccttttaca
    28561 atcttttact ttaaattctg gaatagtttt aaattcctca tcacatattc cattcttatt
    28621 taaatacata caacttgcca ttctaactat tagaccacta ttttttaaat taaacaatac
    28681 agggtctata caccctccat ctccgccagt agtttcacca actaaagtcg caaatttagt
    28741 ttctttacaa aacattgcaa atgactctga tgatgaatat atttttctat caacaagtaa
    28801 gtatatatta cccttaaatt ttgaatcatc tgtagatttt atagtatagg aagtatcttc
    28861 aaaatcatta aaatctttta taatttcttt aggtgcattt tcctttacac ttgttggtaa
    28921 attttctaca ggatttaatt ttatatttct tgcatttgta tattgtttta ctatttcatt
    28981 attatttcta taaattctat aaccatttat tttgacatca ttttttatga gtttagatac
    29041 gattccctgc caataactat cacttccacc taaattacct cttatatcaa taattaaagc
    29101 tttatgtttt tctaaagtgt caatataatc tccaattatt tttaaatcat tatttataga
    29161 gccattcttt gatgacattg atggtaaata catatatcca atctgaccct taataacatc
    29221 ctttaaaatt aattcttttt ttacaaaaat atcatctggc atttttattt taagattcat
    29281 agagtcatat ctatctacaa cttttttatc attaagaaaa tcataccaat cattattaga
    29341 gtatgatttc ttaaaaagtt catatctttt cttattatct attacttctg tgtgtttatt
    29401 atttaaatca gataatatag atgacatttc ttctataaat tcttcatcat tttcagtgtt
    29461 ttttattcgt tttgtatatt catccttatt tgctaaccaa tcaatattat taagcctctt
    29521 atttacacct agatatggat atcctgtctt tacaacatta tacacataat taaagtcatc
    29581 caccttttcc tcttcagaca actgattctt ttgagaataa gtagaattac ctaataagat
    29641 tataaatgct aaaataatta ctaaaaataa tactttcttt ttcatgtaat tctcatccac
    29701 tttcagattt tatattttaa tacattgtat cattatttta ttatcaccta aacagttaaa
    29761 agaaattctt gaagatatat tccactatta ttctctttaa aaatttttat ttgtattttc
    29821 aaaattattt catgaaagtt ataaaataac aattatattc aaatatctat tttactgcta
    29881 tatcctgaag gtaaattctt atcagtgata tactaaaaaa gatatgctaa aaaatttatc
    29941 cattataatg acttaaattt agatacttta ctgattttta tttattagtt gagaaagata
    30001 ttgataatta aaaatattga taactataga aatgattatt ttttatagaa attttaagga
    30061 tataaactaa ttatacttaa gtctatatcc ttaatttatc atgattatga gaatttttac
    30121 aaatacttat ctttgtccgt tttagaataa aaacaagaac atatcctgtt attttattca
    30181 aacatccaaa tttaattact acacaattac ttattagaaa ttgtatctac ttcatatata
    30241 tatctgttaa gtatagcttc tagcatttct tgtcttccag acttattctt tataactggc
    30301 atttgcagtg cataagattc taactcttta aatccaacct taccttctac tatatcctta
    30361 cctatacctt cactaaaact tgcatatctt tctttagtaa agttttcaaa tacctcatct
    30421 tctaataatt tatgagctat taataatccc tttgcaaatg tatccattcc tgcaatataa
    30481 gctaggaata agtcttctac ctcaaaagat gctcttctta ctttagagtc aaagttaaat
    30541 cctcctggtg ctattccacc ttgctttaac acttcataca tagcaagtgt tgcatcatat
    30601 atatttgttg gaaattggtc tgtatcccaa cctaataata ggtctccttg atttgcatct
    30661 atactaccta aaacattgtt tattcttgct atatttaatt catgttggaa agtatgtcct
    30721 gcaagtgttg catggtttgc ttctatattc attttgaagt atttatccag attatacttt
    30781 cttaaaaatc ctaaaacagt agcagtatca aaatcgtatt gatgtttagt aggctctttt
    30841 ggcttaggct ctattaagaa ttggccagtg aatcctattt ccttagcata atctacagcc
    30901 atttgtaaga atcttgcaaa gttatccatt tcaagttctg tattagtgtt aagtaaagtt
    30961 tcataacctt ctcttccacc ccagaataca aaattttctc ctcctaagta cttagttatt
    31021 tccatagctt ttttaacctg agctgctgca tatgcatata catctgcatt acatgttgta
    31081 gatgcaccat gaacaaatct tggatttcca aacatattgg cagttcccca taataacttt
    31141 atacctgtct tttccatatt aacttttata tactcaacta tttcatctaa tatcttattt
    31201 gtctcttcta aatctcttcc ttctggtgct atatctctgt catgaaaaca gaaatactca
    31261 attcccatct tagacataaa ttcaaatcct gcatcaactt taatctttgc tatctcaatt
    31321 gggtctgtta tattattcca aggtctctct actgtgccta ctccaaatgg gtcattaccc
    31381 tctccacata aagtatgcca atagctcatt gcaaatctta agtgttcttt catagtctta
    31441 ttacctacca cttgttcagg attgtagtat ctaaatgcta attcattgtc agattttact
    31501 ccttcaaatt ttatctgtcc tattccttta aatatttcac tcatttcatg tcctcctaat
    31561 attttacaca tataatatat gtagtatgtt ttcttaattt aaaactattt tctatcttta
    31621 tttttctttt taagctaatt taattattta tttttgcatt aactacttca tctaataact
    31681 taaagtcatc tttcaaagat ttgtatattc ttttatacaa tctatgatat atattgtatg
    31741 tatctacatt ttcacttatt ggttctaatt tagttgaagt ttttattata gcatcacatg
    31801 ctttttgtat attttcatat attccagctc ctactaatgc aagaattgca actccaagtg
    31861 ctggtccttc acttgaattt atagtatata catcttgatt aaacatatct gcttgcatct
    31921 gtctccatac tttacttttt ccacctccac ctgaggctct tacttcatta acgtctatat
    31981 taagattctc tattatatcc atacagtctt taagactata tgaaacacct tccattattg
    32041 accttgcaat ttctttttta gaatggattg gagataatcc aaagaacaca cctcttgcat
    32101 aagggtcaag atgaggagtt ctttctccca tcatatatgg taagtaaagc aatccattac
    32161 atcctgttgg tacttgactt acttgattat ttataatctc atatacatct tcacctaaag
    32221 aatttgaaac ttccacttca ctttgacaga aattatcttt aaaccatttt aatgacaagc
    32281 cagctccttg agtaactccc ataacatgcc atgtatttgg tattgcatga cagaaagtat
    32341 gaactctacc ttctttatca atttttggct cttttgtata agcaaatact acacctgatg
    32401 tacctatagt agatgaaact actccatctt taactattcc atttcctata gctcctgctg
    32461 cttggtctcc agctcctcct accactattg ttccttcttt aagccctgtc aaacttgcta
    32521 catctctagt cacataacct gtaatctctt gtgattcata aactttacct aaaagatttt
    32581 tatctatatt taacttttct agtacttcat cgctccaatc tctttttctt atatcgagca
    32641 actgcatacc acttgcatct gatacctctg tagcatattc acctgtcaat ttgtatctta
    32701 tataatcttt tggaagaagt attttattag tatttttata tatatctggt tcattgtttc
    32761 taacccataa tatctttgat gctgtaaatc ctgtaagtgc tggattagca gttatttcaa
    32821 tcagtctttc ttcacctact aaatcagtta tctcctcaca ctcttttact gttcgttggt
    32881 cacaccatat tatagagttt ctcaatgttt taccttcatt gtccagcata actagaccat
    32941 gcatctgtcc tgataatcca attcctttta tacattcact gcttatattt gaactttgaa
    33001 ctacttctct tatagattcg actacagctt tccaccaatc atttgcatcc tgctctgccc
    33061 aacctgattt ctcttgtata agaggatatt catatgtaca actttttata gtatttccta
    33121 gtttatcaaa taaaactgtt ttagtacctg atgtaccaat atccacacct aatacatact
    33181 ccaacttcat ccctccttga atgccacttc ataactatcg ttttcctatc ctaatttttt
    33241 tatattttag gtatatttta cttgctttat ttttgttagt atattaaact aacttatgaa
    33301 ctaataataa aatatttaat tatctttgtc aatgcaaaat aaccttttat ttttgtgtaa
    33361 aaagtattac aatattattt taaggaggaa tatcaaattg gttactgata aatacactat
    33421 tcgagaaatg aatgaaagat tggtacttga acaaattata aaaaatggtc ctatttctag
    33481 ggcaagtata gcttctacta taggattgaa taaagcaact atatccgcta ttaccaaaaa
    33541 acttattgat gaatctctag ttcatgaaat cggaattgga aatagtactc atagtggcgg
    33601 aagaaaaccc atattattag tatttaataa atgtgcaggg atttctttaa gtatggacat
    33661 tggatacgac tatatatttt cttctctatc ttacttagat ggaactatta taaattctaa
    33721 gaaattaaca gatatacaag taagtaaaga caatgttata caattgatag atgaaattat
    33781 aaatagttat aacatatcca aaatagacac tccttataag gtaattggtc ttactttggc
    33841 tatacatggg attacttgtg aaaataaagt attgtttact ccatattaca atcttaatga
    33901 gattgactta tatagcatcc ttagcaaaaa gtatgacttt cctattcata tagaaaatga
    33961 agcaaactta acagctttag ctgagaatac tttttcaact gtacataact cactacttag
    34021 tctcagtatt cacagtggat ttggttcagg cattataata aataataaat tatatagtgg
    34081 cagaaatggt atgagtggag aaattggtca cactatcatc atgcctaacg gtaaactatg
    34141 tccttgtgga aatcgtggct gtttagaaca gtattgttca gaaaaaaagg tatttgaaca
    34201 gctttcttct ttagaaaata ttcctaaaat agattctgat atagtaaagc aactatatta
    34261 tgaagataac cataatgcca aaaaagttat tcatgagttt tgtagttact taacaatagc
    34321 tataaataat gctattacaa cttatgctcc tgaaataata tatttaaata gccaaataat
    34381 tagtgatata cctgagatat tacagattac aaaagatatg ttagttagct cttttaacaa
    34441 aggaataaat atagaaattt catcattagg gtctgaggca tctctatatg gtggctctgc
    34501 tgtaaatatc aagagctttt tgaatataca aaatttaact ttaattaatg aaatataagg
    34561 gttatgacta tatacagcca taacccttta aattatacat tctaaaatta gatttattat
    34621 atagtttatg caagattagc tatatttttt aaaaattgta tatcaattaa gtattaacat
    34681 aagtacttcg ttttaaatat taatataatc ttcctactca tcatcagata ataaacttgc
    34741 attttgttca accatagaaa tattatcttt acctattttc tctaattttg ctgccaattc
    34801 ctttgtatct aaaaaagctg attcaataac catacctaaa tttagccctg aaataatttt
    34861 aattcgactg tcattattgg ctactaataa agcagcattg catggagttc cacctagtaa
    34921 atctgccatt ataattattt ctgaactttc cttgtacact tctaaagctt tttttaattt
    34981 ttctattgtt ccttctattc catcatcttg tttcatattt acagtaggat aatctataga
    35041 atcccctatt atcatttttg cagaatttaa gacttcttca gccatattgc catgactcat
    35101 caaaataata ctattcaatt taatacacct ctttaaatct ataagatgtc tacaagataa
    35161 gttttcttat catcaggcgt cattatagtt gtaatttcaa ttccttcatc taaaagtctt
    35221 ttaaatgctt ctttctcttc ttcagtaaca ctgatattag gtcttagaac tgttgtatct
    35281 tttctacttg acatatttcc tacatttata ttatgtattt taaatcctgc ctctacaaat
    35341 ggaataaggt ccacaggaga cttaacaatt aataatacat tttgtccttc atactttcct
    35401 gcagtaatat tttttatagc agtctcttct gtaattatag atgacgctat acctgcaggt
    35461 gtagccattc ttaaaacttg tttttgaaca gaattgttag ctactgcatc atttactacc
    35521 attaatcttg taacacccaa tttattactc cacatagttg caacttgacc atggattaaa
    35581 cggtcatcta tacgaatatt tttaatacct ttcatttcca tatctaatat catcctttcc
    35641 ttattttaaa atacctaatg catataaaat tattgaaaca accattactc ctaaaattaa
    35701 gtatataggt tttatattct ttttaagagc ccaataaaca atcacaacta gaattgcagg
    35761 aactaaccca ggcataattt ggtctaatat ttcttgacct ttcattgtaa aatcaccttg
    35821 ttgaaagttc aaagcaacat tagcttttac aactgaaggt attaatgcac ctacaaccat
    35881 taaacctaaa atagatgtac tctcagttaa aatctttaaa cttttttcaa ttgaagatat
    35941 tagcttagta cctgatgtat aaccagcatt aaatagtggt atacttaata atttcaatgc
    36001 tacactcact acaatccaca gtaagattcc aaatggactt ccatctatcg ccatattagc
    36061 tgctatagct ccaaaaattg tccacggaat aacgacaaat aaactatctc ctaaacctgc
    36121 tactggtccc atcaagcctg ttttaattga agcaacagcc tcttcagtct cttcacttga
    36181 taactcctcc attgctacat taatacccaa aatataaggg gcaacccaag gattagtgtt
    36241 aaaaaattgt aaatgattta atacagcact ttgtaacttt tctggattat ctttgtatac
    36301 tacttttaaa aaaggtagta ctgcataaca gtatgccaag gcctgcatct tctcataatt
    36361 tgaagaaaca gaactagtaa aaaaccagcg ccataagaca ctttttttca ccttttcatt
    36421 tgatttattt aatgatacct tatcactcat cttcgtccat acctcctact acagtatatt
    36481 gttgttcttg attttccaaa ttctttttgt aaattataag tgcaattgct ccaccaatta
    36541 aagctacacc taataatggt actttcatat atactgctaa aacaaaacca attactaagt
    36601 aactaaaata ctccttagca ggaagatatc taagtaataa tcctatccct actgctggaa
    36661 gtagtcctcc agctactgtt aaaccacctg ttaaccattc aggtgtatat ttcaaaatgg
    36721 tattaattaa agaaggtcca aatattacag atagagcaac tggaatacct gttgtagctg
    36781 ctgttaatag tactcctaac atttgcatat aggttatatt tttataattt ccttttttag
    36841 ctccatcttc tgctttatga actagccata taccaatagt atttctaaga acatctaatt
    36901 gtaccatcaa taaagcaact ggaataccta tagagattcc tacagatgct tcttgcttag
    36961 tcgtaatagt tataaatgtg gctactatac ttgctgtttg ataatcaggt attgatgctc
    37021 caccaaagtt actaatacct aatgataata gctgtaatgt acctccaata tataaccctg
    37081 tatttatatc tcctaagata agaccagtaa taaaacctgc tgttactggt tgatatgttc
    37141 caaacattgt tgaatttttt tcatagttta taaaaaatcc atatagtacg attaataata
    37201 attgccataa ttgtggctcc attatgattt cacctctccc aaaatatttt ttagttcttt
    37261 aaaattataa ctggaatctt gctttaggaa aataggaatt tcttccagtg ggcattcaac
    37321 ttcataagtt ttcccacctt cataactaac tccactaaat atattttccc atgtatgtcc
    37381 ttttggtaaa tatacttttc tacttctatc tttataattc attattggag ctaccaaaat
    37441 ttcatctcca agcatatatg tattatccac ctcccaagtt ttatcatctt caggaaattc
    37501 ataaaataaa gttctcataa ctggtgttcc atcttcatgc gcttctttca tcagtttttt
    37561 taaataagtt tttaagctct ctctaatttt tatgaatttt gtaagaatta cttcaacttc
    37621 ttcaccataa gaccatattt cattaggagc tccagttacc attgagcctc cacctttatt
    37681 tgataatggt ttactatgag gcaatctatc tccatgcatt ctcaaaattg gtgaaaaagt
    37741 agcatattgg aaccatctta ccataagttc tctaaattct gggtctttag gatttcctcc
    37801 atggaaacct ccaatatcag tagtccacca tggtatacct gccagtccca tatttaaccc
    37861 tgtatttact tgattattaa aagcttcaaa actagaatca atgtcaccag accatactaa
    37921 agctccatac ttttgagctc ctgcccaagc tcctcttaca agagttacaa cagactctat
    37981 gtcattatgt aaaccatcat aaatcatttt taaataatca ataggataaa tattaccaca
    38041 acttaaaaca tttccttttt tatatctata gttatcaaaa tcatacacag aatagccagg
    38101 ttcagctaca tctaaccaat aatagtcaat cccaagttgt ttataatttt tatctattct
    38161 atcccaaaca tattctcttg cattttcatt tgtcatatct acaaagactg tatttccttg
    38221 aatttgcatt gtcattctaa caccacgatt aacattgact aaatagccat tttctaaata
    38281 atcattgtag ttttctgcat cactttgaac tgtaggccat acagatacta ttggttctac
    38341 tgaatactct tctttcaatt ttttaactaa ttctttagga tttttccaat aatctaagtc
    38401 aaatttatat tcaccttgct taggccaatg aaaatagtca attgcaattg atgaaagctt
    38461 aattcctctt ttagaatatt ccttcacaac atctaaaact tcttctgaag ttctatatct
    38521 tagtttactt tgccatagtc ctaaaaggtt ttcaggcatc ataggaacag ttccagtaac
    38581 ttgagaataa tttttattta actcttttgg gctttctcca caagtaatcc aataatctat
    38641 aaaatttgta gaaaacatct tccattctgt catattttta gcaaaagata cttttccaat
    38701 tcccggatta ttccataaaa gtccataacc tagactagaa atataaaaag gaactgatat
    38761 ttgagaattt ctttgggcta actccaaaac agtattcttt aaatctaaaa atttatgttg
    38821 atattgtccc attccaaaaa tcttttcaga aggctcagat tcaaatctag tagttacttc
    38881 aaattctcca ctatagcttg gtcgatattc tcttgatttt aactttagag tagagttaaa
    38941 gtctttggta atctcaattg tccctacatc ttctccacca tcatcatgtt ttacagctct
    39001 taatcgaata tattctttca ataatatttc atttttatca ttataaaaag taattctatc
    39061 tctatggtct aagacagctt ttatctttcc atttttaatg attgcacttc catcttcatt
    39121 tttattaatt gtaatatcat ctttatttaa cttaggtttt tcgttaagag catagttttc
    39181 atcaacaaaa ttttggtcta caaacgacct aatacgtaaa gagttttttc cccatgcttc
    39241 tattcgcaat agttcattgt caaatctttt ttcaatatag tcttcagata tttttatcac
    39301 ggctacctcc taaatcaatg gtataatatt ctatctttgt gtagcttaag ttaaataatg
    39361 tcgtttagta tcgttattta taaattaggt tttatatata attcatttgt acattaaact
    39421 aacttaccaa taatatactt tatttgactt tgtttgtcaa tcgctttccg gattttagta
    39481 aaattttcta atatattgct ggaaagtcgt tcttaatatc ttttatttat acttttaata
    39541 tctgtgatga tacctatata catctagttt ttttaaaaca catacaggaa taacatttgc
    39601 ctattatgta gataatatcg gacttgaaaa tatgtatagt gaccttataa atacagataa
    39661 taatatatta gatattgttc aaaacaatgg attttataat tataaataat ttattaaatt
    39721 atttaagaaa atatacaatt gtataccaag tcaaaaacga caacaaataa ataaaactaa
    39781 aaaagatgtt gtctcaaaat atagataaat ttatttttca ttgctaaaat gattaaaata
    39841 tatttgattt aatatacttg atttaatata aaaaaagagt gtctcataaa ctaaaaagtt
    39901 cacttttaga cactccttta tatatattat ctacttctta attcatttat tacctctcta
    39961 cattttcttt caactagtgg atacatcttt ataagtacta attactccac ttaaaaatga
    40021 ttcaggtact gtccatcagt catatttttc tgccaaatat aatggtgttt cataatgaga
    40081 caataaatat ttatatctct acttatcttc tctaagctcg tcaaatccaa ctataggtat
    40141 atttaaatta tattctttaa gtagcttttc tagctcttct ataaaaatac ctttcccatc
    40201 caccatttgt atatcattta ttttatccat caattcattg caaccactta actcaccaaa
    40261 ccaacgttta gaactacatg tcttattata accacaactt ggactgccat ctattgcaat
    40321 gatacttttt atatcataat cattttttaa atattcatca aactgcctta catgaggtat
    40381 taacatttgc ctacattgtt ctctaaaaaa caaattgtca aactgttctt ttacatgtcc
    40441 ccacctattt attccataca taatcatttc tgggcatggt agttgaatta ttccataccc
    40501 tttatttatt aaatctatcg ctatattttg tgctccctta aattctgaca atccctctac
    40561 tttagaatta caatttaata tacaatgaca tactactaca atctctctat ttctcttcat
    40621 aataatctcc ttagttattc ttaattttaa tgatactaca tattttgata attatattat
    40681 ttatttgttc tatatttcca atattctata tagaaatata caattagtaa tcttttataa
    40741 tctatactat gataaatgta tatatttttt taggaggtat tataattgga tactaaaaaa
    40801 gtcacatttt cttcaatgtg catagttatt aatattgtct taggtatggt tatatctatg
    40861 ataaatatac cattattatt tttagataca attggtactg tacttggggc tgtcgtatta
    40921 ggtccttttt ggagtgctct tattggtggg tgtacaaact tagttttagg tgttatatca
    40981 ggtcctacaa atataccttt tgcccttgta aatattgttc ttggtcttat tgttggatat
    41041 atttctaaga aaaaaggttt tggttataaa gaagctatta ttacaggagt aattttatct
    41101 attgtttgtc ctttaattgg tactcctatt tcagttttat tgtttggtgg tttaagtgga
    41161 agtggtgctg atttattggt tggtttttta gttcagtctg gtcagaagat atttactgct
    41221 gcgttctttc caaggattct tagtaatata gtagacaaac ctttgtcttg tattatggtg
    41281 gtatatttta taagtaaaat gcctaaaggt tttataaaac aatatagtaa aaatacttct
    41341 agttcatatt aataaatcat ttattatgta agatttatta ctctttaaaa tgctatatac
    41401 tcatttttat ataacatttt tattaataat ttaattagat agtatttgta ttattttaat
    41461 taaacgtaac ctcttgatat aaatttgagc tataaatcta tatcaagagg tgctatttta
    41521 tttttaatat aattaatatt ctattacgca aaaaatacat atatttcatt attttatgga
//
LOCUS       DAJMZY010000027        38455 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.027, whole genome shotgun sequence.
ACCESSION   DAJMZY010000027 DAJMZY010000000
VERSION     DAJMZY010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 38455)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38455)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38455
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.027"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            280..735
                     /gene="smpB"
                     /locus_tag="OE968_001380"
     CDS             280..735
                     /gene="smpB"
                     /locus_tag="OE968_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HCP7218667.1"
                     /translation="MAGKKILATNKRARHEYFIEETYECGIELKGTEVKSIRQGKVNL
                     SDGFASVDNSEVFLKQVHISPYEQGNIFNVDSLRVRKLLLHKHEIRKLIGATTIKGYS
                     LIPLSLYLKNGKVKVEIALAKGKKLYDKRQDMAKKDAQRRIEREMTGKY"
     gene            893..1242
                     /gene="ssrA"
                     /locus_tag="OE968_001381"
     tmRNA           893..1242
                     /gene="ssrA"
                     /locus_tag="OE968_001381"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            1357..3384
                     /locus_tag="OE968_001382"
     CDS             1357..3384
                     /locus_tag="OE968_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HCP7218668.1"
                     /translation="MSIDNNFNHVAFLWNIAESLRGTYKEEDYRKVMLPLIVIRRFDC
                     LLDDYDREIIKSVYEEYDFLPEEERDELVIVDLKENHDINLQFYNVSDFTWKKLLDDS
                     ENIKSNFEEYLNGFSNNVKEIIGKFKFKDEINQLDKKDKLYAVLSKMYEVDLHINSVS
                     NNKMGYIYEEMLRRFTENSAAGEQYTPREVIRLCMEILFMGKENFLTEEGKVISIADF
                     CCGTGGMLSIAEDYVEKINPSAIVNVYGQELLDESFAICQADMLMKGQNPDNIRLGNT
                     LTQDRFNGEKIRFLISNPPFGVTWKDEEKKVKEEADLGFDGRFGAGTPRVSDGSLLFL
                     QNMISKMYDDEEGSRIAIIFNGSPLFTGDAGSGESNIRKWIIENDLLEGIIALPTDMF
                     YNTGIATYIWVLTNKKEAKRKGKIQLVNASEYYQLMRKSLGNKRKEISLEQIEQIKEI
                     YEKFEESENSKIFDNEDFGYRKVTIERPLKLSFKVNEEAIENVKNTTQFINLAVSKKK
                     DIEVKEKEEAEGKIKQDKLIKLLESFDNTLEYMDRDKFIKDLKAKSKEFDIQLSAGLI
                     KAIVNTIGVRNEDAEVCKDSKGNIESDSSLKDTESIGLKDDVYEYFEKEVKPHVNDAY
                     IDESSINNIGYEIPFTRHFYKYEELRSFAEIMKEVESLESEIALKIRKVLG"
     gene            3384..4775
                     /locus_tag="OE968_001383"
     CDS             3384..4775
                     /locus_tag="OE968_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010233411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HCP7218669.1"
                     /translation="MGYRYRSDDELKDSGVEWLGKIPKDWEVRQLKRVLSDRKENNEP
                     IKTSNILSLTIEKGVIPYSEKGTGGNKAKEDLTQYKLVYPNDIVLNSMNVIVGAVGLS
                     KYFGCASPAYYMLYKINANDDIRFYNYIFKSKLFQDSLKGLGNGIMMKQSETSGKLNT
                     IRMRIPMEKLSSVKIPIAFNLDQEKIANFLDEKTSQFDSIISKKEKLIERLEEAKKSL
                     ISEVVTGKVKVVKTDDGYELIKRSSEEMKDSGVEWLGEIPKEWDIKRLRFLGKLQNGI
                     SKSSDSFGYGYPFVSYSNVYRNIELPHIVEGLVNSTEEERKIYSVEEGDVFFTRTSET
                     VEEIGFASTCMKTIDNSTFAGFLIRFRPNDKRLYKGFSKYYFRCDLNRKYFVKEMNLV
                     TRASLSQNLLNNLSVVLPKYEEQVEIYNALELKVSYINLSINKLKYQIEKLKEAKQSL
                     ISEAVTGKIEILD"
     gene            4837..6108
                     /locus_tag="OE968_001384"
     CDS             4837..6108
                     /locus_tag="OE968_001384"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218670.1"
                     /translation="MDKNIFQININTDVLIRLRNQINEEYYISYRKEFYDKNNKKHRA
                     WDKICAIMDRLDDTVDYLNKLKLNTGKYRRSAFDFFEFMNQASVVMDCITHLAKIFEV
                     PYEEVETSTEIFNELGKEGKGTDKKYFEYLRSLCSVHPMETSRHKIYQENSFECSPYV
                     VWNDKSIWTNDASDLYAVVYTSKDNDSFKRIHIYMNQIFEYVKRRVNFIENIIEHIEK
                     YQQEIIEIFRNTPIKKEEDFESYIDYLRNLKKEIEIRYGNDSFHELNYLIELFDLPLS
                     NPDNEEKMNLYKNALKYAIKFEHNSIQNMTNEGYKNNGILYPQVNITTTLLEELISLN
                     SGSEERRKYRYAIEKTSYLSYDSCWSDREWAYDQIDDMMPFLERYVTFDKAQSDFEHY
                     VLVKLALYLECLENECLINKNVPNDKKFRIK"
     gene            6143..9124
                     /locus_tag="OE968_001385"
     CDS             6143..9124
                     /locus_tag="OE968_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="HCP7218671.1"
                     /translation="MLPKEKHLEESIENHLVSIGYEQGHSQEFDLENCLFVDDLFRFL
                     ENTQKELLDEFKYNRGSNYKKAFIDLLNSNIKRRGLISVLRNGVEDIMMNGKFQLFYN
                     KPNLTTNKTAYENYKQNIFKITRQLKYSSKHNNTLDIVLSLNGFPVIVMELKNQFTNQ
                     NVYNAIKQFKKDRNPKETLFGFNQRVLVYFAVDTDEVYMTTELKGDKTFFLPFNKGNN
                     RGKGNPVVEGKEKTSYLWEEILTKDSLLDIIKRFYFIQEDDKGNQRAIFPRFHQLDAV
                     RKIVEDLKINKVGKNYLIQHSAGSGKTNTIAWTSHRLSSLHDEENNAIFDSIIVVTDR
                     KVLDKQLQNAIYQLEHKNGLVVKIDEDKNSSDLADAIVNRAKIIITTIQKFQYALPKI
                     EQLDKRRYAVIIDEAHSSTSGENMNALKETLAGKTLEEAKVIDAENEKNEKSSIDKMN
                     ELIEKRTNLGNISFFAFTATPKNKTMQVFGRIGEDGLPHEFHLYSMKQAIEEGFILDV
                     LKNFMPISVYYKVGKKIIDNPEFDKGEAKRAINKFVSLNEHNIRQKVETIVDDFVDNR
                     SMWLEGKAKGMIVTASRLHAVRYKLAIDQYIKEKGYDMKALVAFSGTVKDGDDEYTEV
                     GMNKEVAPDITDSNLPNIFDKNEFKLLIVAEKYQTGFDQPKLCAMYVDKKLDGVKTVQ
                     TLSRLNRTYPNKQTFILDFQNSVEDIQDAYKPYFEMTNIDKVTDPNVVNDLWYQLHEY
                     AVYTDEEVNDFTVLFYKEKRTSSQDAKMNNLIDKAVERYCYLEEDDEKKSDEFKKKCQ
                     KYITFYNFLIQIYPIKNLNLLRLQVYLVALLKKLPKKSKQRIDLDDMLSLDYYKLQKL
                     GLDDKKGTDISLYNGEGELVGISETATSRVSEADEEYLEDIIKKINDVFGVGLTEDDR
                     IMINTYEEMFKNDKDIMDIAKANSYEDLVSTFGKKYFKRGIVKTKNRNDRLVKEILTN
                     NNLQNYMIHYLAEKIYEEANR"
     gene            complement(9183..9353)
                     /locus_tag="OE968_001386"
     CDS             complement(9183..9353)
                     /locus_tag="OE968_001386"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218672.1"
                     /translation="MNNDKPFIEFEEEVDFILTECKKEGVSIDRDTIELILDLDLKFL
                     ELKGIATPLEDE"
     gene            9634..9969
                     /locus_tag="OE968_001387"
     CDS             9634..9969
                     /locus_tag="OE968_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218673.1"
                     /translation="MIKLWKKEDLNLLLEYPKEVVENVDNVINILDENYGCNRKLTDD
                     GGYVCIIEDIKEVENLKSNILKGLVEEFSDVIYEDEVNTYNSTLYLLSSDYSVTVISK
                     NEETEYLLK"
     gene            10033..10491
                     /locus_tag="OE968_001388"
                     /pseudo
     CDS             10033..10491
                     /locus_tag="OE968_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427593.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="JAB domain-containing protein"
     gene            10631..10924
                     /locus_tag="OE968_001389"
     CDS             10631..10924
                     /locus_tag="OE968_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218674.1"
                     /translation="MFKKENRYMTKEIAENLPIEIAILLWNLIDDLTTEKDYLQLFEI
                     NPIGLGVVEIVHKQEVPEYEARIYIQNDKIKDKLKIYVIDNVEYRTMMFSNEY"
     gene            10951..11547
                     /locus_tag="OE968_001390"
     CDS             10951..11547
                     /locus_tag="OE968_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218675.1"
                     /translation="MINNKSEIINKLFFNELKELIDKYNNIDDKTVDVIEKIFTCIED
                     EEIKNYLIRDNCKLQELVNTYNKLEDLNIDEAIFFAWYNLTINTISIDKASEYYDDLT
                     TSNYIEVENHIIYTNERDLRKYAEDELETMLSMEHHIDRLLHKDMLIDMWLNNTSKEE
                     VIEEILMSDDIEDILNLSPEYAFTLANGIEYRYSEKEE"
     gene            11700..11969
                     /locus_tag="OE968_001391"
     CDS             11700..11969
                     /locus_tag="OE968_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003487728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mor transcription activator family protein"
                     /protein_id="HCP7218676.1"
                     /translation="MTNNNNNCDYKGIYADMVEVLGEEIVIKLHKYYRGQQITFPMKL
                     YSIEYVERYIVKNYRTKTIKEMCRELGYTEGWIKQLINKNRLNSK"
     gene            11995..12237
                     /locus_tag="OE968_001392"
     CDS             11995..12237
                     /locus_tag="OE968_001392"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218677.1"
                     /translation="MILTVLAILMGTGIFFLINSMLDITYFGCGPIGFLWFGCFIVSY
                     AILTSLGGIVLGLLKWIVIGLIILFVIGLIANKIND"
     gene            12443..13576
                     /locus_tag="OE968_001393"
     CDS             12443..13576
                     /locus_tag="OE968_001393"
                     /inference="COORDINATES: protein
                     motif:HMM:NF012938.1,HMM:NF016983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosome-binding GTPase"
                     /protein_id="HCP7218678.1"
                     /translation="MQDFDFISETIKKFQSDLENMDKVNILVVGKTGVGKSTLINNIF
                     REELAETGIGRPVTQHLKKISKEGLPINLYDTKGLELEEDVQETIKKEILDEIENCNR
                     NSLERNDKSELMHVCWYCINTSVARCEETDIKWINELSEKIPVIVVLTQGFPRKKARE
                     LKSSIDDLNLNCKNVIPVLAEQLVEEEDEIVIKSYGLDKLVEVTYQVIPKEVKKAFVN
                     VQKVDIKKKVEESRKWVLGYVGGSGAIGFSPIPFSDAPLLATAQVAMISHITVIFGLQ
                     VDKALLTAIVSSIGGVTSATLLGKTLVSNILKFIPGAGTIAGGAISGSVAALTTTALG
                     MAYISVLEYILNENMKGNEVNNTEIAEKMKDAYKDQLGMLSKK"
     gene            14340..14585
                     /locus_tag="OE968_001394"
     CDS             14340..14585
                     /locus_tag="OE968_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218679.1"
                     /translation="MRSVTVEDGDERFAIEKIYIKSLQRYEVRICLYRDCRDRINKLI
                     PRPVDLTMDKFVALILVGLKAGVLDDDFKQELIKGLA"
     gene            14933..16294
                     /locus_tag="OE968_001395"
     CDS             14933..16294
                     /locus_tag="OE968_001395"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218680.1"
                     /translation="MKGNINKKDIDLSKITFDKFLEDEGLQNRERDYLYVDDYDNTLD
                     TQEFKLHIIEENTDNTYIDKDKYWYLDLDDSLFEYEEDEDTIAKTLYSLIDIRIKFLK
                     HVEYRKYINLGVIDEEYFDEIKSFLKFYIVAKTKKNELGNSNLKQMAIDIFDKERFED
                     DISDDDMENISEWIGEDQNFKMFYDKVCRDLSNSTQDKEILKLAGIRNNKVKHYKGRK
                     ISRKCKLELKSLTKMWEYETKLTHDANKAHKKIKSNMLEKMTDKNYKNIYEYLNNEII
                     NSNEEYKNIYFYSLELKLANELRKCTLKNLNKIKDIENQVKFISYTIAYIHIVPVLTI
                     REKLSDKLFNILSTNEGKDIEKFTKEVSLIMRIINIECLELLNIVSKNNYYKNFSEKE
                     LEEFKSIYNINNGRKSFENKYKIKVDYNIDDVRKYGEVIKAINIESKKKIVDRIKKKR
                     KSN"
     gene            16484..16801
                     /locus_tag="OE968_001396"
     CDS             16484..16801
                     /locus_tag="OE968_001396"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218681.1"
                     /translation="MTNFKSVKVELILLIECEEGNRNELEGMIDEGVLNEKEYSLTIL
                     GSTEYEDNARAIYILMNTGGSYEKNLQRLSRLHLKIENLLKDTNVKYRGISLVPNIVK
                     WDK"
     gene            16813..18576
                     /locus_tag="OE968_001397"
     CDS             16813..18576
                     /locus_tag="OE968_001397"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218682.1"
                     /translation="MSKAINREELIKLYEEIGLNVLDNNTVMNSSNKKICNFLVNIIE
                     QRVIDGKMYLCINAMGINGELLSEVILDSNTINRTTWVIENWGFKYSIDKKYINDFIE
                     LIQHLCMNIKTKYIYDHTGWIYQDNKWIYLHGGGVIGGSDVQVELDESIDNYILPDKI
                     SDINKACEMSLKLVDLIEDDKGIIFSSLVYLSPLIEIISRKIKPPENIVWTYGKTGSR
                     KTAVSKVVLSHFGDFNKKIPATFNDTITAIELKANKLKDSLYLCDDFAPKQDFRDKKI
                     QDSKAESIIRMYGDRVGKGRSSNKLDIKDAKRPRGMILITGEDVICGESSNARLLSIE
                     LNRSSVDLNILTELQNNSHLLGEAMRGYIEWLLSEMGNIDELSNILLYNFKSYRDEIR
                     EQYKDDIHGRTIESSAWILVGFSCMLNYIRDKGVIDKYEDDEYMDRAIKVVERLIEEQ
                     IKLISRNSPIDIFLNTLKESINSKSIRIATLNDQNQVIEDKLEYICGYKDKEYYYFYT
                     DKVYSFIEFENKKRGIHLGISQRQLVKQLRDSGIVKVDSNNDSPKKTIHTKDASDSTG
                     YTTIRPRMLQIERSIIENFQI"
     gene            18639..18794
                     /locus_tag="OE968_001398"
     CDS             18639..18794
                     /locus_tag="OE968_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218683.1"
                     /translation="MTETYKISIGRKDLYSKDYKVVERTDYEKRHTVNISRSLVDILS
                     ILVKEDR"
     gene            18881..20446
                     /locus_tag="OE968_001399"
     CDS             18881..20446
                     /locus_tag="OE968_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HCP7218684.1"
                     /translation="MTGKKAVVYARFSSDNQRDESIDAQLRAINEYADKNNIKIVNQF
                     IDRAKSATSDKRPEFQNMIKFCEADTTGISMVIVHKLDRFSRDKYDSAMYKQKLKVKG
                     IRVVSVLENLDNSPESLILESVIEGMAQYYSANLAREVAKGQKENALKALHNGGDAPL
                     GYDVAHDKTYTVNEEEAQAVKIIFDRYIKGYSYSKIIDELNILGYKTKRGNKFGKNSL
                     HGILNNEKYTGVYVFNKTQRKGVDGKRNGHKQKSEEEIIKIEGGMPQIIDKGVFKQAQ
                     DMIQKRKKTPGAHKATTTYLLTGLIKCGECGHAFQGNKRKDSYGNEYVSYRCGCRKQK
                     RECNNREIKRDYLEEFILQELEKNILNDEAIPILSKALNEKLNDKNESNAELLKNLEQ
                     KLDKVNKEISNILNAIMNGIVNSMLKDKLDELEQVKFNLDLKMNELKIENKVVDGVGV
                     TEDQIRGMFSRFKEFVLERNIPECKKFIGDYIKEVIVYKDHIEVIFNVVFCFVDNDIT
                     HDLHIITERGKIT"
     gene            20592..21884
                     /locus_tag="OE968_001400"
     CDS             20592..21884
                     /locus_tag="OE968_001400"
                     /inference="COORDINATES: protein motif:HMM:NF014177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA adenine methylase"
                     /protein_id="HCP7218685.1"
                     /translation="MADIFTVLNYQGSKKRLLDFIYENTQEYIDSDKAFLDICSGTSA
                     VAYNMKRHFTVYTNDSENYAYQISNSIVKNNERYNFSQSDEMIIREKYNINLQRLNNI
                     FNDMVNQEDMLLEQEDADGLIELYSNCPCIWKNNVDIEIEGNTIQSIYDLRKCKRDIP
                     NVLFTLYYSSSYFGIKQSMEIDSIRYAIEFIESEITKSILFTSLFFAMKECVFAKDGH
                     MAQPLNMETGKKRMLRLKARSIYDIFIDKLKEFNTEEFVLSQKENKCFNKDFRTLLET
                     EESIKDEVGFIYIDPPYTDMQYSRYYHILNTVVLYDYPEISLSRGTISKGIYREGRYQ
                     SPLSQRKHALNEIDFLFSFCKENKINVALSYAYPIDTEKQATNRYTASIDDLINVAKK
                     HFGDNVKVVHEEYSHANNRNSDKKNVLEYLIMGIHNKE"
     gene            21887..23506
                     /locus_tag="OE968_001401"
     CDS             21887..23506
                     /locus_tag="OE968_001401"
                     /inference="COORDINATES: protein motif:HMM:NF013704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA adenine methylase"
                     /protein_id="HCP7218686.1"
                     /translation="MDKINKLKERIANIEATNKNDIYSSNLYWSQKPFNICDEIIEHL
                     SEDGDIIFDPFMGSGVTVIEALKKEYKRNAIGCDINDAPIFIVKTLLEKYNVPKIEKD
                     IKELNNKLSKLSTYYSTKCRECGEVVTISKTIFDKENRNAKCELKSIHYKCKECKNDF
                     KGEPNETEISKFFIDEELKNIDDFQFIANSRLAVGEGDTVRTIFSNRNLIVLDKILGH
                     IDEYKNSESYEPMKYILLSILHLSKITDTHSNSQWPLWIPKKDCVEKNVVELFIKNSK
                     KTIKALKLASKYLCENRENVELIKNLDRGKFKLIKDGVQNIEDDVIPNEFVDLIITDP
                     PYMGQVLYSEYMQLYKPFMDLEFELENEIVISSAPARDKGKVLYFDMMNSAFENISRV
                     LKVGKYMCMYFHDSNLDVWDNIIDIMTNNNLKYMGQIHVSKNKNTLKNILSPKKSLNG
                     DCIIFFKKDLNINYDINEVDNIEDKINNIAQAIIDIKGYASTPELYDNGALEYIISNG
                     KLKEISKKYKDLTSIFEQRFNWDKERGVWTV"
     gene            complement(23631..24782)
                     /locus_tag="OE968_001402"
     CDS             complement(23631..24782)
                     /locus_tag="OE968_001402"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218687.1"
                     /translation="MKKLTIRLKDDFHKDLLDLVAFKNDSINSYVINLIKNDLSKNTN
                     LLRSYDNMIRDNITNVLITQKINELKAIQDGIFKEYKVNDILSNSKIYEVMTANSLNH
                     ILIPGHSGSRDAKDEFGNEFEYKHFKKSSSNHSWTFNDFSDTSIAKLKKAKAVIFAHI
                     NDVDFPYPGKLDWYYSIPGDIMCEYLLKYTQSIQNSRKMINVSPNQLESRLNASKIIP
                     SAQNGVYDKYLSAIYKASSELEELTGVKNLLTSNKFWELIVALELNHQVNPEQGGREG
                     AHDAYDSEGNPYEYKVSKNHAWNFQDISDNVLNKYYNDKAIILAVVDKENIEVEHIYS
                     TEPADVVPLLRKKLQEKINRCLEKGSPIRRLQVSLSKSDLTRVNAKKLY"
     gene            25288..25503
                     /locus_tag="OE968_001403"
     CDS             25288..25503
                     /locus_tag="OE968_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3791 domain-containing protein"
                     /protein_id="HCP7218688.1"
                     /translation="MDERKLEFSIFCIEALAEKLNIDSEGVYKLLKHDTDILDNYIIP
                     CYEALHSQSKGYIVEDLMQVLKEKGVI"
     gene            25503..25982
                     /locus_tag="OE968_001404"
     CDS             25503..25982
                     /locus_tag="OE968_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3990 domain-containing protein"
                     /protein_id="HCP7218689.1"
                     /translation="MIVYHGSYCVVKTPSITFSRDSLDFGKGFYVTSIKTQAINWTER
                     FKKRGKKAYLNSYSLDIDKLKENCKVKIFDSYNLEWLDFIIECRNMSDIYMKYDIIIG
                     GIADDKIYNTIELYQDNLIEKDEALKRLKYYKPNEQICITNQNVIDKYLKFRYEEEV"
     gene            25988..26218
                     /locus_tag="OE968_001405"
     CDS             25988..26218
                     /locus_tag="OE968_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218690.1"
                     /translation="MEANKTLLQILYKKIILEFSKQTGKSLEESMDYLYTSETYKLIS
                     EGVSDMHCKGHIYLAQELMLENGLMYHKGYPR"
     gene            complement(26334..27500)
                     /locus_tag="OE968_001406"
     CDS             complement(26334..27500)
                     /locus_tag="OE968_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HCP7218691.1"
                     /translation="MATKRANGEGSIGKYKDGWRSRIMIGYNEDGKPLRKEFYGKTQK
                     EVKDKLDAYKKQYYLSSDISDDKITLEHWFYNWLFEYRIKDLKPKSFERYESIYRNYI
                     KDTDLGNVKLKYLRVSHIQKYYNRLLDSNKSIPTIRQINTKLKTCLSEAEKQGLIQRN
                     YCTMVNIPVEKKENKLEILTLEQQKSFIKAIDGHKLEVLFLLALGTGLRLGELLGLKW
                     FDIDFKKSNLTVKRTLQRTYFIDKTGNRELKVLEQGPKTSNSYRTVPIPKDVLNKLKE
                     HKVNQNTDILKAGELYINNNYVFCNELGIPIDDKRPLRNLKSILNSLNIEPIKFHGLR
                     KTYATRLFENDVPPKTVQVLMGHYDISITLNIYTQVMEDKKVEAVEKLDKIFSL"
     gene            complement(27490..28242)
                     /locus_tag="OE968_001407"
     CDS             complement(27490..28242)
                     /locus_tag="OE968_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HCP7218692.1"
                     /translation="MNKSYIPKYTHKFPTNIPHGDKKYTLTYIRRMISEFVYDMGNLE
                     NNPFTFPEVQTLLDGITVGGHKLSDQNQILNIKSSWDYVIKLSNKENLSLNKDTICSI
                     HKIVAKDEALIVGDFRNGNIGIAGTTQYECIEATLLNDLFVNDINIINKITNPLEKAI
                     IINLWLSYCQFFYDGNKRTARLTSNLILINNDIGVLSIPAKHKQEYNTLMLNFYETLE
                     ADEVIKFLLEKCITFFDGYNYKSYKELFKNGN"
     gene            complement(28334..28825)
                     /locus_tag="OE968_001408"
     CDS             complement(28334..28825)
                     /locus_tag="OE968_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCP7218693.1"
                     /translation="MMNNTIGEKIKQYRKSINMSRDELANKIGCSVHAIAKYEQNQRM
                     PSLDMIRKIATALSIAINKLIVEENDLDTLTNNNINLKVFDKELDLVIHILENYGYDI
                     KTDYKKKFEITDNADTIKPINLNFSDFKDFSKNLNWVINGLVENFIQENSNGLIEDED
                     EEY"
     gene            complement(28822..29020)
                     /locus_tag="OE968_001409"
                     /pseudo
     CDS             complement(28822..29020)
                     /locus_tag="OE968_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729178.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(29077..29838)
                     /locus_tag="OE968_001410"
     CDS             complement(29077..29838)
                     /locus_tag="OE968_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCP7218694.1"
                     /translation="MQIGKNLKKIRKQKELTQIQLAEISGISRNALINYENDKRIPSI
                     DTLSKLAKALKIEKTIFYFDIENEVMTNEDVLYLLQSLFPEEYYSFDEFLNAISNLME
                     DDIRITSSLLLGAWSDKDQYYKLGEKLELNENQVYNWILSDCISNTELDFSLHPDDIK
                     EIIKNDVLTKQSIDELLDIGLSEESIETIYDYFSDSTDNGSNIRLKKLISQKENITIK
                     NNDYFKLLQENNELKEKNEKLENTLKEIKKLLTKI"
     gene            29985..30185
                     /locus_tag="OE968_001411"
     CDS             29985..30185
                     /locus_tag="OE968_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCP7218695.1"
                     /translation="MGINLKIFRIKKGLKQQELADRVGISRYYLSNLETGKANNPSND
                     LMIKLSRALDTTVEELFFSKED"
     gene            30189..30503
                     /locus_tag="OE968_001412"
     CDS             30189..30503
                     /locus_tag="OE968_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218696.1"
                     /translation="MKENNNLEVLKTLQATLNIIVKNEEEAQEKKQGYKIIENAKRNK
                     AELITCKEASKLYPIGESKFRQLCHSKNKGFPCIWINNRVYIIKNKLDDWFIENANGI
                     KL"
     gene            30525..31268
                     /locus_tag="OE968_001413"
     CDS             30525..31268
                     /locus_tag="OE968_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218697.1"
                     /translation="MSNKGWIKLYRELLDKSIWKDIKPERKVILITLLLMASHKENHV
                     FIDNKKIKIKFGQFISSYSKIAERCGKGVSYQMVRSCLLVFKNAGFLTYETTNKYIVI
                     TIENWELYQENIENQQPNQQTINNQSTTIKNIKNENNIIYSEIISKFNSTCIELSKVK
                     KLTDTRKRRINSRIKEYDKETVLEVINIVSKTSFLNGNNNTGWKANFDWIMNSSNFTK
                     ILEGNYNSKEIVINKETGIYNPDDSQLKW"
     gene            complement(31974..33887)
                     /locus_tag="OE968_001414"
     CDS             complement(31974..33887)
                     /locus_tag="OE968_001414"
                     /inference="COORDINATES: protein motif:HMM:NF020926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1998 domain-containing protein"
                     /protein_id="HCP7218698.1"
                     /translation="MSIKLDDKTHNLRINQATSVFGPGAMLDFIDQTLMTAHPNYWTN
                     TIKIQDDRLQATLRVNELRTPPTIDDRSSVPFVRFPRWYFCPKCRKFMPIEDWEKLYK
                     NAHKDKPMKIPICLTCSTKKSTKQLVPTGIITICEHGHIDDFPWVKWVHFRNKSGRKE
                     ICENPQILMKTGKSNLGLEGIELECSCGAKANMKGAFMRLKSSKSNDYGVPSEYKEMF
                     KCSGNSPWYNKKVNKCTKYSFASQRGASNVYYPKIESSIIIPPYSDTLNSKVLSSKGY
                     DTFKKFLDRAIKKNKLERFMDEDFEDFASDIAKETGFDTDKVSIVLKDLLPFEDSSPS
                     TTTRNQYREEEYEALIGNIDAKSKKTNDFTIEEQNLSDYDIPNFSKIVLVKRLREVRA
                     LTGFSRVNPPDNNIFGEEDIDDSCNDTKVISLRSRDCKKSFYPASEVRGEGIFIEINN
                     DMVKSWISSNPKIQDNASILNSRYNKDINVNDKAYRKITPKFLLLHTLAHLIIRELSF
                     VCGYATSSLRERIYCNNSENEKVMSGILVYTASGDSEGTLGGLVRQGMHDSLPSILNS
                     ALNRALWCSNDPICIDSTGQGRNSLNLGACHSCTLLPETSCEEYNLLLDRSMLIGDMD
                     NRDIGFFKNLILI"
     gene            complement(33889..37416)
                     /locus_tag="OE968_001415"
     CDS             complement(33889..37416)
                     /locus_tag="OE968_001415"
                     /inference="COORDINATES: protein motif:HMM:NF012493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HCP7218699.1"
                     /translation="MNCSELRDKTLDLVRKELLGPGSEDLCENIKYEIITDSPIERYS
                     TGILYPLNNNIDVSNTSEYDGEDNVFTSDDTQNELDRAISMSNETLPSSMGMTFFLKK
                     DAEVINFRVNYATYRNALYTDCHVKYTGDDFYSSNTINEYVELRGSFLYLKQKLTSEK
                     VYNLLKKHDLLDNAEAKFVLYKLANQCPDDENKTGGYVRVPHENLIVSIDMDKNYIKK
                     PISKDLDIVLSKRIYSNDFVSITCMLVNSQSGPKKYNNTIFQPELMVLAEDNNDLEFI
                     DIFTAGSVNTFKKLDSEEISLDLLYRNKKTFATGHGVAIDQDIQNDALIKLCTEFIPH
                     FEVPKLDFNVDELSDVSRELLSMKNLSDISDLSKDKKIYFLYKFVDAYDIWIDDLEED
                     SKDLSDVFKDVAYEHIKNCRDTKSRMLEGINLIKSNDEVYRAFSLMNRAILMQRCHSI
                     HITDRLPGSNNLDYIDYSNDNSAWRPFQLAYILTCLSSIENPDSKHRDLVDLLWIPTG
                     GGKTEAYLGLSAFTIFLRRIRNKENGNGTAIIMRYTLRLLAAQQFIRASILICACEII
                     RKENKSELGKKEISIGLWIGSDQTPNFNDEAEEMLNNLTGNNIKFRSSINSEYELDNL
                     KSKYNKFQLLKCPWCGTKLVKEWDKTSKKAVGDWGYRIKSRPKKFYLCCPEEDCSFED
                     MLPIQVVDEEIYNNPPTLLFGTVDKFAMITWTTEVASLFALDDDNSNLSPELIIQDEL
                     HLISGPLGTMVGLYETALDAMCSYKGIKPKIIASTATIRKAQNQVKNLYNRNVAQFPP
                     PGLTSSNSFFVKEMPLSKKRGRLYVGVIPSGKTQVTVEVRLMSALLQRLKMMENVELN
                     LLDKYWTLVSYFNSIRELGKCSTLLNDDIKDNMERLCKRVSAHPYQSLRNLNEQRELT
                     SRLTSTKINTTLDELSNTLTSNNLTVDTLLASNMISVGVDVDRLNLMVVVGQPKLTSE
                     YIQASSRVGRSNEGLIFTLYNPTKTRDRSHYEQFFSYHQSFYKFVEPTSITPFSEPAR
                     ERGMHAVLISMIRHILGLQANDLASRFSKNMDGVEDLKNFIIDRSIDIFRENNQNADD
                     NIVNEFKSEISSELDIIMDLWHDKAQISDKDNLLHYYKRPSKFDNKIYNNLLIPYDKD
                     VITNEKQTLNSMRNVDKQCTVEIIELEEN"
     gene            complement(37434..38396)
                     /locus_tag="OE968_001416"
     CDS             complement(37434..38396)
                     /locus_tag="OE968_001416"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218700.1"
                     /translation="MNQINSARNKIEKNNKIYNLLDIKPFKPTYETNKLEAYSTDSPI
                     SDDDSMDEYISNYKFDINLNEIILSLSINQGIYNSKKEHVTSFMISDNNEYIFCTKKA
                     IAYSIDWDKKSVRKKKLSEAKVNDWFLFVDDYLNEEGELVINVIQKLLELNLLPSHYL
                     DDYKLTNSWKSELKNYISYSKYNYNDVSNSLAVLGEKINPITIKNWVTNKRLIGPIYL
                     KTFEKIFKVIDSKLDHTEVYDATKSIRSLHTKIKKSIDTFVSDNFFSSKSDIIKDEVS
                     AVVLSMLGNTNDYVTPVQIREIHSCDKYLSPHLVNKVLDLYSVY"
BASE COUNT        15333 a         4265 c         6084 g        12773 t
ORIGIN      
        1 tataatatgt aatatttttg ttttgaaatt tataaattag tattactggt tagagttagt
       61 ttagtattaa gtatattcga agtagttttt tagctatttt catacattta tattacttaa
      121 ttatatatag cctaactaac ttaatatatc agtgaaatat tgactaaaat gcctaaatat
      181 gttatcatac aagttagtca aataatttgg caacattaaa tatttagtaa atttctaaca
      241 tttatggaac aaatttctag caaagaaggt gagatttata tggctggtaa aaaaatatta
      301 gcaacaaaca aaagagcaag acatgaatat tttatagaag aaacttatga atgtggaatt
      361 gaattaaaag gaacagaagt aaaatcaata agacaaggca aagttaacct aagtgatgga
      421 tttgcatctg tagataatag cgaagtattt ttaaaacaag ttcatataag tccatatgag
      481 caaggaaata tattcaatgt tgattcttta agagttagaa aactattact tcataagcat
      541 gaaataagaa agcttattgg agcaactact ataaaggggt attcacttat accacttagt
      601 ttgtatctaa aaaacggtaa agttaaagta gagattgcct tagcaaaagg taaaaaacta
      661 tatgataaac gtcaagatat ggctaagaaa gatgcacaaa gacgtataga aagagaaatg
      721 acaggtaagt attaaactag ataaaactgt attttttaga ataaaattct ttattatcta
      781 gaacataaca ttgattttta ttcttaaaag tattatatta tatatacatt aaaaatttaa
      841 taaaaatggt gataaagttt gagaaaagtc tactggacta taaactactc aagggggcgt
      901 aaaggtttcg acgtgggttt ggaacttgag gctgcatgtc gtgttactct gggtcacgta
      961 aaaactgggg aactttaaaa taaacgcaga cgataatttc gcgatagcag cctagttgct
     1021 gctcgtccct cttagtcctc ctgccgacta agactggacg tcattatgca gggaactact
     1081 ttaggggtgt ctcgacttga agtagattaa ttgggactgg ctaagcatag agcctgccac
     1141 ttggcgctat gtgaggtgag atattagtga agttggctaa gcatgtagat gcagcaagga
     1201 aaagatttgc ggacaggggt tcgactcccc tcgtctccac cattgaaatc cacgaaaaca
     1261 tattgatagt ttagtcaata tgtttttttt gtgccttgaa atgatataat tataatataa
     1321 actaatgtaa aatttaacta aaaggagata gtataagtga gtatagataa taattttaac
     1381 catgttgcat ttctgtggaa tatagcagaa agtttaagag gtacatataa agaagaagac
     1441 tatagaaaag taatgttacc actaatagta ataagaagat ttgattgtct attagatgat
     1501 tatgatagag aaataataaa atcagtatac gaagaatacg acttcttacc agaagaagaa
     1561 agagatgagc tagtaatagt agacttaaaa gaaaatcacg acataaactt acaattttac
     1621 aatgtaagtg attttacatg gaaaaaacta ttagatgata gtgaaaatat aaaatcaaac
     1681 tttgaagaat atctaaacgg attctcaaac aatgtaaaag aaataatagg taaatttaaa
     1741 tttaaagatg aaataaatca attagataaa aaagacaagc tatatgcagt tcttagcaaa
     1801 atgtatgaag tagatctaca tataaactca gtatctaaca ataaaatggg atacatatac
     1861 gaagaaatgt taagaagatt tacagaaaac tcagcagcag gagagcaata cacaccaaga
     1921 gaagttataa gactttgtat ggaaatacta tttatgggta aagaaaactt ccttacagaa
     1981 gaaggaaaag taatatctat agcagacttt tgttgtggta ctggaggaat gctttcaata
     2041 gctgaagact atgtagaaaa aataaatcca agtgcaatag taaatgtata tggacaagaa
     2101 ctacttgatg aatcattcgc aatatgtcag gcagatatgc taatgaaagg gcaaaatcca
     2161 gataacataa gacttggaaa tactttaaca caagatagat ttaacggaga aaaaataaga
     2221 tttttaatat caaatccgcc ttttggtgta acttggaaag acgaagaaaa gaaagtaaaa
     2281 gaagaagcag acttaggttt tgatggaaga tttggagcag gtactccaag agtaagtgat
     2341 ggttcattac ttttcctaca aaatatgata agtaaaatgt atgatgatga agaaggaagt
     2401 agaatagcta taatatttaa cggaagtcca ttatttacag gagatgcagg aagtggagaa
     2461 tcaaacatta gaaaatggat aatagaaaat gatttactag aaggtataat agcactacct
     2521 actgatatgt tctacaatac aggaatagct acatatattt gggtacttac taacaaaaaa
     2581 gaagctaaaa gaaaaggtaa gatacaactt gtaaatgcta gtgaatatta tcaattaatg
     2641 agaaaaagct taggaaacaa aagaaaagaa ataagtcttg aacaaataga acaaataaaa
     2701 gaaatatatg aaaaatttga agaaagtgaa aatagtaaaa tatttgataa cgaagatttt
     2761 ggatatagaa aagtaacaat agaaagacct ttaaaactaa gctttaaagt aaacgaagaa
     2821 gctatagaaa atgtaaaaaa tactactcaa tttataaatc ttgcagtttc taagaaaaaa
     2881 gatatagaag ttaaagaaaa agaagaagct gaaggaaaaa taaaacaaga taagttaata
     2941 aaacttttag aaagctttga caatacttta gagtatatgg acagggataa atttataaaa
     3001 gatttaaaag ctaaatcaaa agagtttgat atacaacttt cagcaggact tataaaggct
     3061 atagttaata ctattggtgt aagaaatgaa gatgcagaag tttgtaaaga tagcaaaggt
     3121 aatatagaaa gtgatagttc attaaaagat actgaaagta taggtcttaa agatgatgta
     3181 tatgagtatt ttgaaaagga agtaaagcct catgttaatg atgcttatat agatgaaagt
     3241 agtataaata atataggata tgagatacca tttactagac atttttataa gtatgaagag
     3301 ttaagaagtt ttgctgagat tatgaaggaa gtagaaagtt tagaaagtga gatagcacta
     3361 aagataagga aggtgctagg gtaatgggat acagatatag aagtgatgat gagttaaagg
     3421 atagtggagt tgagtggtta gggaagattc ctaaggattg ggaagtcaga caattaaaaa
     3481 gggtactatc agatagaaaa gaaaataatg aacctataaa aacaagtaat atactgtcat
     3541 tgacaataga aaagggagtt attccatatt ctgaaaaagg tactggtggt aataaagcta
     3601 aagaagattt aacacaatac aaattagtat atccaaatga tattgtatta aatagtatga
     3661 atgtaattgt tggtgcagta ggactatcaa aatattttgg gtgtgcgagt cctgcatatt
     3721 atatgttata taaaataaat gctaacgatg atataagatt ttataattat atttttaaat
     3781 ctaaattatt ccaggatagt ttaaaaggat taggtaatgg aataatgatg aaacaatcag
     3841 aaacttcagg taagttaaat acgatcagaa tgagaattcc aatggaaaaa ctaagttcag
     3901 taaagatacc aattgctttt aacttagatc aagaaaaaat agcaaacttt cttgatgaaa
     3961 agacttcaca gtttgattca attatatcta agaaagaaaa gttaatagaa agattagaag
     4021 aagcaaagaa aagccttata agtgaggttg ttactggtaa ggttaaggtt gttaagactg
     4081 atgatgggta tgagcttata aagagaagta gtgaagagat gaaggatagt ggagttgagt
     4141 ggttaggtga gatacctaag gaatgggata taaaaagact tagattttta ggaaaactac
     4201 aaaacggtat aagtaaaagt agtgattcat tcggttatgg ttatccattt gttagttata
     4261 gtaatgtata tagaaatata gaattaccac atatagtaga aggtctagta aattcaactg
     4321 aagaagaacg taaaatttat tcagtagaag aaggagatgt attctttaca agaacttcag
     4381 aaacagtaga agaaattggt tttgcttcta cgtgtatgaa aactattgat aattctactt
     4441 ttgcaggatt tttaataagg tttagaccga atgataaaag actatacaaa ggattttcta
     4501 aatattactt tagatgtgat ttaaatagaa aatattttgt aaaagagatg aatttagtaa
     4561 ctagagcatc tttatctcaa aatcttttaa ataatctttc tgttgtattg cctaagtatg
     4621 aagaacaagt tgagatatat aatgcacttg aattaaaagt tagctacatt aatttatcga
     4681 ttaataagtt aaagtaccaa atagaaaaac taaaagaagc taaacaaagt ttaataagtg
     4741 aagcagtaac aggaaaaata gagatactag attaacttct agtatcttaa tatagatata
     4801 gattatacat acaaagttaa ataaaaggga gaattaatgg ataaaaatat atttcaaatt
     4861 aatataaata cagatgtact gataagatta aggaatcaaa taaatgaaga atattatata
     4921 tcttatagaa aagaatttta tgataaaaat aataaaaaac atcgcgcttg ggataaaata
     4981 tgtgcaataa tggataggct tgacgatact gtagattatt taaataaact caaattaaat
     5041 acaggtaaat atagacgaag tgcatttgac ttctttgaat ttatgaatca ggcttccgta
     5101 gtaatggatt gtataacaca tcttgcaaaa atatttgaag taccatatga agaagttgaa
     5161 acttcaactg aaatttttaa tgagcttgga aaagagggta aaggtacaga taaaaaatac
     5221 tttgaatatc tacgttcatt gtgttcagtc catccaatgg aaactagtag acacaaaata
     5281 taccaagaaa atagttttga atgtagtcct tatgtagttt ggaatgataa aagtatatgg
     5341 actaatgatg ctagcgattt atatgcagtg gtatacacaa gtaaagataa tgatagtttc
     5401 aaaagaattc atatatatat gaatcaaata tttgagtatg taaaaagaag agtaaatttt
     5461 attgaaaata taatagaaca tatagaaaag tatcaacaag aaataattga aatttttagg
     5521 aatactccaa taaagaaaga agaagatttt gaaagttata tagattattt aagaaatcta
     5581 aaaaaagaga tagaaataag atatggtaat gattcttttc atgaattaaa ctaccttata
     5641 gaattatttg atttgccatt atcaaatcct gataatgaag agaagatgaa cttatataaa
     5701 aatgctttaa aatatgctat caaatttgag cataatagta ttcaaaatat gacaaatgaa
     5761 ggttataaga ataatggaat attatatcca caagtgaata taacaactac attactagaa
     5821 gagctaattt cattaaatag tggtagtgag gagagacgta agtacagata tgcaatagaa
     5881 aaaacatcat atctaagcta tgatagttgt tggagtgata gagaatgggc atatgatcaa
     5941 atagatgata tgatgccttt tttagaaaga tacgtaacat ttgataaagc tcaaagtgat
     6001 tttgagcatt atgtattggt aaaactagca ctttatttag agtgcttaga aaatgaatgt
     6061 ttaataaata agaacgttcc taatgataaa aagtttcgta ttaaataatt atagctaata
     6121 aaatagggag agggaggata ttatgttacc aaaagaaaaa cacctagaag aatctattga
     6181 aaatcattta gtttcaattg gatatgaaca aggtcattca caagaatttg accttgaaaa
     6241 ttgcttattt gtagatgatt tatttagatt cttagaaaat actcaaaaag aattactaga
     6301 tgagtttaaa tacaacaggg gaagtaatta caaaaaagct tttatagatt tattaaattc
     6361 aaacatcaaa agaagaggtc ttataagtgt acttagaaat ggtgtagaag atataatgat
     6421 gaacggaaaa tttcaattat tctacaacaa accaaatcta actactaata aaacagcgta
     6481 tgaaaattat aaacaaaata tattcaaaat aacaagacaa ttaaaatata gctcaaagca
     6541 caacaatact ttagatatag tattatcttt aaatggattt cccgttatag taatggaact
     6601 taaaaatcag tttactaatc aaaatgtgta taatgctata aagcaattca aaaaagatag
     6661 aaacccaaaa gaaactttat ttggatttaa tcaaagagtg ttagtatatt ttgcagtaga
     6721 tactgatgaa gtttatatga caacagagct aaaaggagat aaaacattct tcttaccgtt
     6781 taataaaggt aacaatagag gtaagggaaa tcctgtagta gaaggaaaag aaaaaacttc
     6841 ttatctttgg gaagaaatac ttactaaaga tagtttactt gatattataa aaagatttta
     6901 ctttattcaa gaagatgata aaggtaatca aagagcaata tttccaagat ttcatcaatt
     6961 agatgcagta aggaagatag tagaagattt aaagataaat aaagtaggta aaaattatct
     7021 tatccaacat agtgctggta gtggtaagac taacactata gcatggactt cacataggtt
     7081 atcaagtctt catgatgaag aaaataatgc tatatttgac tctataattg tagttacaga
     7141 cagaaaggta cttgataaac aattacaaaa tgctatatat caattagagc acaaaaacgg
     7201 acttgttgtt aagatagatg aagataaaaa ttcatcagac ttagcagatg ctattgtaaa
     7261 tagagcaaag attattataa ctactattca aaaattccag tatgcactac ctaagataga
     7321 acaacttgat aaaaggcgtt atgcagtaat tatagatgaa gcacattctt caacatctgg
     7381 tgaaaatatg aatgcattaa aagaaacttt agcaggaaag actttagaag aagctaaggt
     7441 aattgatgcg gaaaatgaaa agaatgaaaa gtctagtata gataagatga atgagcttat
     7501 agagaaaaga acaaatttag gaaatataag tttctttgct tttacagcta ctcctaagaa
     7561 taagactatg caagtatttg ggaggatagg tgaagatgga ctacctcatg aatttcattt
     7621 atattctatg aaacaagcga tagaggaagg atttatatta gatgtactaa aaaactttat
     7681 gcctataagt gtttattaca aagtaggaaa gaaaattatt gataaccctg agtttgataa
     7741 gggagaggct aagagggcta taaataagtt tgttagttta aatgagcaca atataaggca
     7801 aaaggttgaa actatagtag atgattttgt agataatagg tctatgtggt tagaaggtaa
     7861 agctaaaggt atgatagtta ctgcaagtag attacatgct gttagatata aactagctat
     7921 agaccaatat ataaaagaaa aaggatatga tatgaaagca cttgttgctt tttctggtac
     7981 tgtaaaagat ggtgatgatg agtatacaga ggtaggtatg aataaggaag tagcaccaga
     8041 tattactgat tcaaatttac ctaatatatt tgataaaaat gaatttaagc tattaatagt
     8101 tgcagaaaag tatcaaactg gatttgacca accaaaactt tgtgctatgt atgtggataa
     8161 aaaactagat ggtgttaaaa ctgttcagac tttatcaagg cttaatagaa cttatcctaa
     8221 taaacaaaca tttatattag atttccaaaa tagtgtggaa gacatacaag atgcatataa
     8281 gccatatttt gaaatgacta atattgataa ggtaacagat ccaaatgtag taaatgacct
     8341 ttggtatcag ttacatgaat atgcagtata tactgatgag gaagtaaatg attttacagt
     8401 attattctat aaagagaaaa gaacttcttc tcaagatgct aagatgaata atttaattga
     8461 taaggcagtt gaaaggtatt gttatttaga agaagatgat gaaaaaaaat ctgatgagtt
     8521 taagaaaaaa tgtcaaaagt atattacttt ttataatttt ttaattcaga tttatcctat
     8581 aaagaactta aatcttttaa gattgcaagt ttatttagta gcacttttaa agaagttacc
     8641 taaaaagagt aaacaaagaa tagaccttga tgatatgtta agccttgatt attataaatt
     8701 gcaaaagctt ggattagatg ataaaaaagg aacggatata tccttatata atggagaagg
     8761 tgagttagtt ggtatatctg aaactgcgac ttctcgtgta agtgaagctg atgaagagta
     8821 tttagaggat ataattaaaa aaataaatga tgtttttggt gtaggactta cggaagatga
     8881 tagaattatg ataaatactt atgaagagat gtttaagaat gacaaggata tcatggatat
     8941 agctaaagct aatagttatg aagatttagt tagcactttt ggtaagaagt attttaagag
     9001 aggtatagtt aaaaccaaaa atagaaatga tagattagtt aaggagatat taactaataa
     9061 taatttacaa aattatatga ttcattattt agctgaaaag atatatgaag aggcaaatag
     9121 ataagatacc tatagagagc taattaactc tccataggta ctttattatg agctattgta
     9181 tattattcat cttctaaagg tgtagcaatt ccttttaatt ctaaaaactt taagtctaaa
     9241 tcaagaataa gctctatagt atctctatct atagaaacac cttctttttt acactcagta
     9301 agtataaaat caacttcttc ttcaaactct ataaatggtt tatcgttatt catatttttg
     9361 ctcctttgat taaatataat gtatttactt taaattatat caaagaagag aaaaaaataa
     9421 cattatttgt aaaaaactat atatatataa tatatagttt taccatatat agataaactg
     9481 tttttaatta aattataaat atatattata ttaatgaatc tatattaaat agatagttga
     9541 gtaagtagta ataccaaaaa tattaaaaag agatgttggt agaaatacga acatctcttt
     9601 tttagtgcaa aaaattaaaa ggaggaagtt aatatgatta aattatggaa gaaagaagat
     9661 ttaaatttat tattagaata tccaaaggaa gtagttgaaa atgttgataa cgtcattaat
     9721 attcttgatg aaaactatgg atgtaacaga aaattaacag atgatggtgg atatgtgtgt
     9781 ataattgagg atattaaaga agtagaaaac ttaaaatcaa atatattaaa ggggttagta
     9841 gaagagttta gtgatgtaat atatgaagat gaagttaata catataattc aacactatac
     9901 ttgttatcta gtgattatag tgttactgta atttctaaaa atgaagaaac tgagtactta
     9961 cttaaataag catatacatt gataaggtgt atatgcttat tttaatttta ataaataaag
    10021 gagaaaagca gaatgaataa aaagagaact cctgccaaga gagttgatat agttttactt
    10081 aaattagtaa aagaacgtag tgttctatat gaaactagaa aaataagtaa tctttatgat
    10141 gcttatagat tagcaaagaa ttttttataa atagtgctag agaaaagttt gtagtggtat
    10201 gtttagatac aaagaattgg ccagtagcat agaggttgta agtataggca ctgtaaattt
    10261 atctatggta tatccaagag aaatatttaa agtagctata ttaaccaatt catctgaaat
    10321 gatatgcttt cacaatcacc caatgggtaa tactgacttt agcaaggaag atagttataa
    10381 ctaatatgct acagaagcgt ggagaaatat tatgcattga attagtagat acatatagtt
    10441 attgtagatg aggataaata ctttagcttt aaagaaaact gtaggatata agagtcttag
    10501 cttaaataaa ttaggctaag gctttttcta tgttccaaaa caattaaaaa taaatcaaat
    10561 ttaggttaag cccggaaagc ccttgaaaaa aataatacat ataaatttaa aactaaatag
    10621 gagttgtaac atgtttaaaa aagaaaatag gtatatgaca aaagagatag ctgaaaatct
    10681 accaattgaa atagctatac tactatggaa tttaatagat gacttaacta cagaaaaaga
    10741 ttatctacaa ctatttgaaa taaatcctat aggattagga gtagttgaga tagttcataa
    10801 gcaagaagta cctgaatatg aagctaggat atatatacag aatgataaaa ttaaagataa
    10861 attaaaaata tatgttatag ataatgttga atatagaaca atgatgtttt caaatgaata
    10921 ttagttaatg attaaaggag agagagtaat atgataaata ataaatctga aataattaat
    10981 aagttatttt tcaatgaatt aaaagagtta atagataaat acaacaatat agatgataaa
    11041 actgtagatg taatagaaaa gatatttaca tgtatagaag atgaagaaat aaagaattac
    11101 ctaataagag ataattgtaa gctacaagag ctagtaaata catacaataa acttgaagat
    11161 ttaaacatag atgaagctat attctttgct tggtacaact taactataaa tacaatatct
    11221 atagataaag caagtgagta ctacgatgat ttaactacaa gtaactatat agaagtagaa
    11281 aatcatataa tatatacaaa tgaaagagat ttaaggaagt atgctgaaga tgaattagaa
    11341 actatgttaa gcatggaaca tcatatagat agattactac ataaagacat gttaatagat
    11401 atgtggttaa acaatacttc aaaagaagaa gtaatagaag aaatattaat gagtgatgat
    11461 atagaagata tattgaattt atctccagaa tatgcattta cattagctaa tggaatagaa
    11521 tatagatact cagaaaaaga agaataaaat aagtatatgt actgaaaaat acgggcttta
    11581 agggcttata cattaaagta catatttgaa aataccatag attttacaag agaaaatcag
    11641 aatgaaactt tttcaaatac tagttattat taattagtgc tagaaaagga ggtggagtga
    11701 tgactaacaa caataataat tgtgattata agggcatata tgcagatatg gttgaggttt
    11761 tgggtgaaga aatagtcatt aaattacata agtattatcg tggacaacaa ataacatttc
    11821 caatgaaact atattctatt gaatatgtgg aacgatatat agtgaagaat tatagaacaa
    11881 aaacaataaa agaaatgtgt agagagttag gatatacaga gggatggata aagcaattaa
    11941 ttaataaaaa tagattaaat tcaaagtaat tagagaagga gattgacagt agatatgata
    12001 ttaacagtat tagcaatact tatggggaca ggtatatttt ttctgattaa ttcaatgcta
    12061 gatataacgt attttggatg tggcccaata ggatttttat ggtttggatg ttttattgtg
    12121 tcatatgcaa tattaacatc attaggtggt atagttttag gattgttaaa gtggatagta
    12181 ataggattga ttatactatt tgtaatagga ttaatagcga ataagataaa tgattaaatt
    12241 actgtagatt attttgataa aataattatt taatatattg aggcattaca tgatagaaga
    12301 ataaatataa atgacttaaa atctttaact taactaaaca aaaaatatat tatttattac
    12361 aaaaaatgac aaaaaaatta aatattatat tgtattatga caatataaaa cattggagtt
    12421 tataaattag gaggaatatt ttatgcaaga ttttgatttt ataagtgaga caataaagaa
    12481 atttcaatcc gatttagaaa acatggataa ggtaaatata cttgttgtag gtaaaacagg
    12541 agtaggtaaa agtacattaa taaataatat atttagagaa gaattagcag aaactggaat
    12601 tggtagacct gtaacacaac acttgaaaaa aataagcaaa gaaggattac caataaattt
    12661 atacgataca aagggattag agttagaaga agatgtgcaa gagactataa aaaaagagat
    12721 attagatgaa atagaaaatt gtaatagaaa ttcattagaa agaaatgata aaagtgagtt
    12781 aatgcatgta tgttggtatt gtataaatac atcagtagct agatgtgaag aaactgatat
    12841 aaaatggata aatgagttaa gtgaaaagat accagtaata gttgtattga cacaaggatt
    12901 cccaagaaaa aaagcaagag aattaaaatc tagtattgat gatttaaatt taaactgtaa
    12961 gaatgtaatt ccagttttgg cagagcaact agtagaagaa gaggatgaga tagttataaa
    13021 gtcatatggt ttagataaat tagtagaagt tacatatcaa gtaataccaa aagaggtcaa
    13081 gaaagctttt gttaatgtac aaaaggtaga tataaaaaaa aaggttgaag agtcgagaaa
    13141 atgggtttta ggatatgtag gaggatcagg agcaatagga ttttcaccaa taccattttc
    13201 agatgctcca ttattagcaa ccgcacaagt tgctatgata tctcatataa cagtaatatt
    13261 tgggttacaa gttgataaag ctttactaac ggcaattgta agttctatag gaggggttac
    13321 atcagctact ttactaggaa aaacattggt atcgaatata cttaagttta taccaggagc
    13381 tggaactata gcaggtggag cgataagtgg ttctgtagcg gcattaacaa ctacagcatt
    13441 aggaatggca tatataagtg tattagaata tatactaaat gagaatatga aaggtaatga
    13501 ggttaataat actgaaatag ctgaaaaaat gaaagatgca tacaaagatc aattaggaat
    13561 gttatctaag aaataattaa ttcaagataa agtataagat taattatagg gaaaaagtaa
    13621 aatttaaagg tatatttggt aaaacataaa caaaaatgat aatggcgtca atattatttg
    13681 ttgtcatatg tagtagctta gtatatatat tattgagtga taggtttaat cataagttaa
    13741 tttacttaga gaaagatata ttagatttaa gaaataaaaa tttgtaacta gctaataaag
    13801 gatcagtata gaaacagata aacaagagga taatgtagat attaaatcta aaaacactaa
    13861 taatgaagaa tataaaactt caaaactatt taggcactag atagagtatt tgctataatg
    13921 aataagctaa tagagaaatt aaaacgttta tagtaagata actaattcaa atacatttag
    13981 tggacttcaa ggaacatttg atacactatc aaactatggt agccaattga tagaccaatc
    14041 atctaaattg aatttatcaa atgttggatg gttagaaata tctgatataa ttacaagtat
    14101 aggaaaggac tattagattc tgaaaatatg tcatttgaag cattaaatat aatgggaaaa
    14161 ataggaaaat ttataaatta tattgaaatt aattatatta actaattaaa tattgataca
    14221 taatgccttg ctacagttaa atgtggcaag gcattatttt tgtaaagaaa ggaagaatta
    14281 acatggcgaa gcaaagtaaa gaggaactat ttgaaaaaga aactaaatat tgcaagataa
    14341 taagaagtgt aacagtagaa gatggagatg aaagatttgc aatagagaaa atatatatta
    14401 agtcattaca aagatacgag gttagaatat gcctgtatcg tgactgccga gatagaatta
    14461 ataaacttat tccaaggcct gtagatttaa ctatggataa gtttgtagca ttaatactgg
    14521 taggattaaa ggctggtgta ctagatgatg atttcaagca agaactaatt aaaggtttag
    14581 cttaggaggt agaatatgac aatagaagag tttactagtg gagtaatgtt tgggatttca
    14641 atttttagtg cagtattaaa gcaagtatta gaaaataaaa aatagtatac aggaggtatg
    14701 agtatgattg gatttataat aggaagtata ataggaattg gactatgtat tagtatagag
    14761 atactgatat cgaaaaatgc cataatatac taagttatat ttaaattatt aatagattca
    14821 tatataattt atttaagccc ttaaagccca gataagttat attaaagtaa agtttgtatt
    14881 tatgtaaatt aaataatata tattattata aatttgaaag gactttataa atatgaaagg
    14941 caatataaac aaaaaagata tagatttaag taaaataaca tttgataagt ttttagaaga
    15001 tgaaggatta caaaatagag agagagatta cttatatgta gatgattatg acaatacttt
    15061 agatactcaa gaatttaaat tacatataat tgaagagaat actgataaca catatataga
    15121 taaagataaa tactggtatt tagatttaga tgatagttta tttgaatacg aagaagatga
    15181 agatactatt gctaaaacat tatatagtct aatagatatt agaattaaat ttttgaaaca
    15241 tgttgagtat agaaaatata taaatctagg agtaatagac gaagaatatt ttgatgagat
    15301 taaatcattt ttgaaatttt atatagtagc aaaaacaaag aaaaatgagc taggtaattc
    15361 aaatttaaag cagatggcta tagatatttt tgataaagaa aggtttgaag acgacatatc
    15421 agatgatgat atggaaaata taagtgaatg gataggagaa gatcaaaact ttaaaatgtt
    15481 ttatgataaa gtttgtaggg atctctcaaa ttctacacag gataaagaaa tattaaaatt
    15541 agcaggaatc aggaataata aagtaaaaca ttacaaagga agaaaaatta gtagaaaatg
    15601 taaattagaa cttaaatcat tgactaaaat gtgggagtat gaaactaaac tgactcatga
    15661 tgcaaataag gcacataaga aaataaaatc taatatgctt gaaaaaatga cagataagaa
    15721 ttataaaaat atatatgaat atttaaataa tgagattata aatagtaatg aagaatataa
    15781 aaatatttat ttttatagct tagaattaaa gttagcgaat gaattaagaa agtgtactct
    15841 taaaaactta aataaaatta aagacataga aaatcaagta aaatttattt cttatactat
    15901 tgcttatata cacatagttc cagttttaac gataagagag aaactaagcg ataagttatt
    15961 taatatattg tcaactaatg aaggtaagga tatagaaaaa tttactaaag aagttagtct
    16021 tataatgaga attataaata tagaatgttt ggagttatta aatatagtta gtaagaacaa
    16081 ctattataaa aattttagtg aaaaggaatt agaggagttt aaatctattt ataatataaa
    16141 taatggaaga aagtcatttg aaaataaata taaaataaaa gtagattata atatagatga
    16201 tgtaagaaag tatggagagg ttataaaagc aataaatata gaaagtaaga agaaaattgt
    16261 agatagaatt aagaagaaga gaaaatctaa ttagattttc tctatttttt ttgaaaaaaa
    16321 taaaaaatat ttggtgaaaa cgtttatctt taggtgatat gagtagtcat tatttattat
    16381 ataatcatat ttgtaggaac gagctaatta ataaaatcta agaacaatag cttaatgatg
    16441 aaaaagtacg gcctttcggg ctttgacaac aggaggtata ttaatgacaa actttaaaag
    16501 tgtaaaggta gaattaattc tacttattga atgtgaagaa ggaaatcgta atgaattaga
    16561 aggtatgatt gatgaaggtg tattaaatga aaaagaatat agtttaacta tattaggtag
    16621 tacagagtat gaagataacg caagggctat ttacatactt atgaatacag gaggatcata
    16681 cgaaaaaaac ttacaacgat taagtagatt acacttgaaa attgaaaact tacttaaaga
    16741 tacaaatgtt aaatatagag gtatatcttt agtaccgaat attgttaaat gggataaata
    16801 ggaggaatac aaatgagcaa ggcaataaac agagaagaat taattaaatt atatgaggaa
    16861 ataggattaa atgttttaga taataacacc gttatgaatt catctaataa aaagatatgt
    16921 aattttttag taaatataat agaacaaagg gttatagatg gaaaaatgta tttatgtata
    16981 aatgctatgg ggattaatgg agagctatta tcagaggtaa tattagattc gaataccata
    17041 aatagaacta catgggtgat tgaaaattgg ggttttaaat attctataga taaaaaatat
    17101 attaatgact ttattgaatt gatacaacac ttatgtatga atataaaaac taagtatata
    17161 tatgaccata caggatggat atatcaagac aataagtgga tatatctaca tggaggagga
    17221 gttataggag gttcagatgt tcaagttgag ttagatgaat caatagataa ctatatacta
    17281 ccagataaaa ttagtgacat aaataaagca tgtgaaatga gtttaaagct agtagactta
    17341 atagaagatg ataaaggtat tatattctct tcattagttt acctatctcc acttattgaa
    17401 attatcagta gaaaaattaa accaccggaa aatatagtat ggacatatgg aaaaacagga
    17461 tcaagaaaaa cagcagtatc aaaagttgta ttaagtcatt ttggtgattt taataaaaaa
    17521 attccagcta catttaatga tacgattaca gctattgaat taaaagctaa taagttaaag
    17581 gatagcttat acttatgtga tgactttgca cctaaacaag actttaggga taaaaaaatt
    17641 caagactcaa aggcagaatc cattataaga atgtatggag atagagtagg gaaaggacgc
    17701 tcaagtaata agttagatat aaaggatgct aagagaccta gaggaatgat attaataaca
    17761 ggtgaagatg tgatatgtgg agaatcatct aatgctagat tattatcaat agaattaaat
    17821 agaagttcag tagatttaaa tatactaact gaattacaga ataatagtca tttgcttgga
    17881 gaagcaatga gaggatatat agaatggtta ttatctgaaa tgggaaatat tgatgaatta
    17941 tctaatatat tattatataa ctttaaatct tacagggatg aaattagaga acaatataaa
    18001 gatgatatac atggaagaac tattgagtct agtgcatgga tattagtagg ttttagttgt
    18061 atgttaaatt atattagaga taaaggtgtt atagataagt atgaagatga tgagtacatg
    18121 gatagagcga ttaaagttgt agaaagatta atagaagagc agataaaatt aatatcgaga
    18181 aactcaccta tagatatatt tttaaataca ttaaaggaat caataaattc aaagtcaata
    18241 agaatagcaa cattaaatga ccagaaccaa gttatagaag ataaattaga atatatatgt
    18301 ggatataagg ataaggaata ttattacttt tacacagata aagtatattc ttttatagaa
    18361 tttgaaaata aaaaaagagg tatacatttg ggaataagtc aaagacaact agtgaaacag
    18421 ttaagagata gtggaattgt gaaagttgat tctaacaatg attctcctaa aaaaactatt
    18481 catacaaaag atgctagcga ttcaacagga tatacaacaa taagaccaag aatgcttcag
    18541 atagaaagaa gtataattga gaactttcaa atataactta taatcaagag tgcttatgta
    18601 ctcttgatta tattctatga taaatggagg atataaatat gacagaaact tataaaatca
    18661 gcataggaag aaaagattta tattctaaag actataaggt agttgaaaga actgactatg
    18721 aaaagagaca cacagttaat ataagtagaa gcttagtaga catactttct atacttgtaa
    18781 aagaagatag atagattaaa atatggttac acacttagtg ttagtgtgta gcctttaata
    18841 tagattaaaa ttagtatatt taaactttgg aggaaataat atgacaggaa agaaagcagt
    18901 agtatatgca cgctttagtt cagataatca aagggacgaa tcaatagatg ctcaattaag
    18961 agcaataaat gaatatgcag ataagaataa tataaaaata gttaatcaat ttatagacag
    19021 agcaaaatca gcaacatcag ataaaaggcc agagtttcaa aatatgatta aattctgtga
    19081 agcagataca acaggaatat ctatggtaat agttcataag ctagatagat tttctagaga
    19141 taagtatgat tcagctatgt acaaacagaa attaaaagta aaaggaataa gagttgtaag
    19201 tgtattagag aacttagata attcgcctga atccctaata ttagaatcag ttatagaggg
    19261 aatggcacaa tattacagtg ctaatttagc gagggaagtt gctaaaggtc agaaagaaaa
    19321 tgcccttaaa gcccttcata atggaggcga tgcaccatta ggttatgatg tagcacatga
    19381 taaaacatat acagttaatg aagaagaagc tcaagcagta aagattatat ttgatagata
    19441 tattaaagga tattcatata gtaagataat agatgaacta aatatcttag gatataagac
    19501 taaaagaggt aataaatttg gtaagaatag cttacatgga atattaaata atgagaaata
    19561 tacaggagta tatgtattta ataagactca gagaaaaggt gtagatggaa aaagaaatgg
    19621 acataagcaa aagagtgaag aggaaataat aaaaatagaa ggtggtatgc cacaaataat
    19681 agacaaagga gtatttaaac aagcacaaga tatgattcaa aaaagaaaga aaactccagg
    19741 tgcacataaa gctactacta catatctatt aacaggacta attaaatgtg gtgaatgtgg
    19801 acatgcattt caggggaata agagaaaaga ttcttatgga aatgaatatg tttcatatag
    19861 atgtggatgt agaaagcaaa agagagaatg taataataga gagataaaaa gagactattt
    19921 agaagagttt atattacaag aacttgaaaa gaacatatta aatgatgaag ctataccgat
    19981 tttaagtaaa gcattgaatg agaagctgaa tgataagaat gaaagtaatg cagagctact
    20041 taaaaatcta gagcagaaac tagataaggt aaataaagag ataagtaata tactaaatgc
    20101 tataatgaat ggtatagtaa atagcatgtt aaaagataag cttgatgagc tagaacaagt
    20161 aaagttcaac ttagatttaa aaatgaatga actaaagata gaaaataaag ttgtagatgg
    20221 tgtaggtgta acagaagatc aaataagagg tatgttttca agatttaagg aatttgtact
    20281 agagagaaat atacctgaat gtaagaagtt tataggagac tatataaagg aagtaatcgt
    20341 atataaagac cacattgaag tcatattcaa tgtggtcttt tgttttgttg acaatgatat
    20401 aactcatgat ttacatatta tcacagaaag gggtaaaatt acatagtaaa tatatatttt
    20461 ataaaagtaa atatcagata ttatttagat aaaaattatt tttgaaaata ttagttttaa
    20521 aaaatatatt tatataatta taaaataaaa tggtataata aaactttaaa tatgataaag
    20581 aggtgagact attggcagat atatttacag tactaaatta tcaaggtagt aaaaagagat
    20641 tattagattt tatatatgaa aatacacaag aatatattga ttctgataaa gcttttttag
    20701 atatatgctc aggaacgagt gcagtagctt ataatatgaa aagacacttt acggtttata
    20761 caaatgatag tgaaaattat gcatatcaga tatctaattc aattgttaag aataatgaaa
    20821 gatataactt tagtcaatca gatgaaatga tcataagaga aaaatataat attaatttac
    20881 aaagattaaa taatattttt aacgatatgg taaatcagga agatatgtta ttagaacaag
    20941 aagatgcaga cggtttaata gagctatatt caaattgccc atgtatatgg aaaaataatg
    21001 ttgatattga aatagaaggc aatacaatac agagtatata tgatttaaga aaatgtaaac
    21061 gagacatacc gaatgtgtta ttcacattgt attattcaag tagttacttc ggcataaagc
    21121 agtctatgga gatagattct attagatatg ctattgaatt tatagaaagt gaaataacaa
    21181 agagcattct ttttacaagt ttatttttcg caatgaaaga gtgtgttttt gctaaagatg
    21241 gtcacatggc acagccatta aatatggaaa caggcaagaa aagaatgtta agattaaaag
    21301 caagaagtat atatgacata tttatagata aattaaagga atttaatact gaggagtttg
    21361 tattatcaca aaaggagaat aagtgcttca ataaagactt tagaacatta ttagaaacag
    21421 aagaaagtat aaaagatgaa gttggtttta tatatataga ccctccgtat acagatatgc
    21481 aatactcaag atattatcat attcttaata cagttgtttt gtatgattac ccagaaatat
    21541 cattgagtag aggaactata tcaaaaggga tatatagaga aggtagatat caatcacctc
    21601 ttagtcaaag aaaacatgca ttaaatgaga ttgatttctt atttagtttc tgtaaggaaa
    21661 ataaaataaa tgtagcatta agttatgcat atccaataga tacagaaaaa caagcaacta
    21721 atagatatac ggctagtatt gatgatttga taaatgtagc caaaaaacat tttggagata
    21781 atgttaaggt agtacatgaa gaatatagtc atgcaaataa tagaaatagt gataaaaaga
    21841 atgtacttga atatttaata atgggtatac acaataagga gtaaatatgg ataaaattaa
    21901 taaattaaaa gagaggatag ctaatataga agcgacgaat aaaaatgata tatattcttc
    21961 taacttatat tggtcacaaa aaccattcaa tatatgtgat gaaattattg aacatttaag
    22021 tgaagatgga gatataatat ttgatccgtt tatgggatct ggggttacag ttatagaggc
    22081 tttgaaaaaa gagtataaaa gaaatgctat tgggtgtgat ataaatgatg caccaatatt
    22141 tatagtaaaa acattattag aaaaatataa tgtgcctaaa atagagaaag atattaaaga
    22201 gctaaataat aaattaagta aattatcaac ttactattca acaaaatgtc gtgaatgtgg
    22261 agaagtagtt actatatcga aaactatatt cgataaggag aataggaatg caaagtgtga
    22321 gctaaagtct atacattata aatgtaagga atgtaaaaat gactttaaag gtgaaccaaa
    22381 tgaaactgaa atatctaaat tctttattga tgaagaatta aagaatatag atgattttca
    22441 attcatagcc aattcaaggc ttgcagttgg cgaaggtgat acagtaagaa ctattttttc
    22501 aaatagaaat ttaatagtat tagataaaat attaggacat atagatgaat ataaaaatag
    22561 tgaatcttat gagcctatga agtatatttt attatctatt ttacatttaa gtaagattac
    22621 agatacacat tctaattctc agtggccttt atggattcct aaaaaagact gtgttgaaaa
    22681 aaatgtagta gaattattca taaagaatag taagaaaacc attaaggcat taaaactagc
    22741 atctaaatat ttatgtgaaa atagagaaaa tgtagaacta atcaaaaatc tagatagagg
    22801 gaaatttaaa ttgataaaag atggagttca aaatatagaa gatgatgtta tacctaatga
    22861 atttgtggac ttgataataa cagatccacc atatatggga caagttttat attcagagta
    22921 tatgcagtta tataaacctt ttatggattt ggaattcgaa ttagaaaatg aaatagttat
    22981 atcaagtgcc ccagctagag ataaagggaa agtattatat tttgatatga tgaattctgc
    23041 atttgaaaat atatctagag tattaaaggt aggtaaatat atgtgtatgt acttccatga
    23101 tagtaatcta gatgtatggg ataatataat agatataatg accaataata atttgaaata
    23161 catgggacaa attcatgtaa gtaagaataa aaacactctt aaaaacatac ttagtcctaa
    23221 gaagtcgtta aatggagatt gtataatttt ctttaagaaa gatttaaata taaactatga
    23281 tataaatgaa gtagataata tagaagataa gataaataat attgcacaag ctattataga
    23341 tataaaagga tacgcatcaa ctccagagtt atatgataat ggagcactag agtatataat
    23401 atcaaacgga aaactaaaag agatttctaa aaagtataag gatttaacaa gtatatttga
    23461 gcaaagattt aattgggata aggaaagagg ggtatggact gtataataaa taaaaagcat
    23521 ctatagataa ttatagatgc tttttattta tattttatag taaactaaat atttaataat
    23581 ttctaatttt tatacaatat gttaaaggat tggctatcca aagatattat ttaatataat
    23641 tttttagcat taactctagt taaatcactt ttagataatg aaacctgtaa tcttctgata
    23701 ggagaaccct tttctaaaca tctattgatc ttttcctgta acttcttacg aagaagagga
    23761 actacatctg ctggttcagt tgagtagata tgttcaactt ctatattttc tttatcaaca
    23821 actgctaata ttatagcttt atcattataa tatttattta gtacattatc agatatatct
    23881 tgaaagttcc aagcatgatt tttagaaact ttatattcat aaggattacc ttcactatca
    23941 taggcatcat gagcaccttc tcgtccacct tgctctgggt ttacttgatg gtttaattct
    24001 aatgcaacta ttaattccca aaacttatta cttgtaagta aatttttaac tcctgttaat
    24061 tcttcaagtt cacttgaagc tttataaata gcacttagat atttatcata aacaccattt
    24121 tgagctgatg ggattatctt acttgcattt aatctagact ctagttgatt agggctgaca
    24181 tttatcattt ttctggaatt ttgtatactt tgagtatact ttagtaaata ttcacacatt
    24241 atatctccag gtatagagta ataccaatca agctttccag ggtaaggaaa atcaacatca
    24301 tttatatgag caaatataac tgccttagct ttctttaatt ttgctatact tgtatccgaa
    24361 aaatcattaa acgtccaaga atggttagag ctacttttct tgaaatgttt atattcaaac
    24421 tcatttccga attcatcttt tgcatctcta gaaccactat gtccaggtat tagtatgtga
    24481 ttaagtgaat tagcagtcat aacttcatat attttgctat tagaaagtat atcatttact
    24541 ttatattctt taaaaatacc atcttgtata gcctttagtt catttatttt ctgtgttatt
    24601 aaaacatttg ttatattatc tcttatcata ttatcatagc tccttaataa attagtattt
    24661 ttagataagt catttttaat tagatttatc acataactat tgatgctatc atttttaaat
    24721 gctactaaat ccaataaatc tttatgaaaa tcatccttga gtcttatagt tagttttttc
    24781 aagctatcac ctcggatatt aattagatgt gccgtcgaga taagtataat taagcaggtt
    24841 tataaagtca aggattaaaa aaattaaatt atagatatat aaaagtatat atagcaatat
    24901 agataaatag ctaaactatt aatcgtgggt attattcttg cgattcgtct ccaccaattt
    24961 tgaaaaaaga atgatgaaat acttggaaat actagtcttt gttgactagt attttttatt
    25021 ttggagaaga aatccaccaa ccgtacccca accacagaaa atgaggtttt tttgggggta
    25081 tattggggtg catttaggct gtataaaaag tttttatttg tttattattt tatttgttta
    25141 ttattttatt tgtttattat gataataggt aacatagaat tttaatatct actttatgat
    25201 ataatatttt tataaatgta agacagttta agttgttaat tagtaaaaat atatattata
    25261 taagcttgat aggagttgag gtttgtaatg gatgaaagaa aactagaatt ttctattttt
    25321 tgcattgaag ctttagcaga aaaattgaat atagattcag aaggagttta taaacttctt
    25381 aaacatgata ctgatatttt agataactat ataatacctt gctatgaagc actacattct
    25441 caaagtaaag gttacatagt ggaagattta atgcaagtac ttaaagaaaa gggtgtgata
    25501 taatgattgt atatcatggt tcatattgtg tggtaaagac gcctagtatt accttttcaa
    25561 gagattcttt agattttgga aaaggattct atgtaaccag tataaagaca caagcaatta
    25621 actggacaga gcgttttaaa aaaagaggta aaaaagcata tttaaatagt tattctttag
    25681 atattgataa attaaaagaa aactgcaagg taaaaatctt cgatagttat aatttagaat
    25741 ggcttgattt tataatagaa tgtagaaata tgagtgatat atatatgaaa tatgacatta
    25801 taataggtgg tattgctgat gataagattt acaatacaat agaactgtat caagataatc
    25861 ttattgaaaa agatgaagct ttaaaaagat taaaatacta taaaccaaat gaacaaatat
    25921 gtataaccaa tcaaaatgta atagataaat atttaaagtt taggtatgaa gaggaggtat
    25981 aatgattatg gaagcaaata aaacattatt acaaatacta tataaaaaaa tcatattaga
    26041 attttccaaa caaacaggta agagcttgga agaaagtatg gattatttat atacttctga
    26101 aacatataaa cttataagtg agggtgtatc agatatgcac tgtaagggtc atatatactt
    26161 ggctcaagaa ttaatgttag aaaatggatt aatgtaccat aagggctatc caagataaat
    26221 aattaaaact agatacgaaa taaggataca atataatata aaattaattt gtatccttat
    26281 tttgattttg taattaacta tatgaaatca caatatttat atgtatttga tttttacaat
    26341 gaaaatattt tatccaactt ttctacagct tcaactttct tatcttccat aacttgagta
    26401 tatatattca aagttattga tatatcataa tgacccatta aaacttgtac agttttagga
    26461 ggaacatcat tctcaaaaag tctagtagca taagttttcc taagaccatg aaactttata
    26521 ggctctatat ttaagctatt taatatagac tttaaattcc ttaaaggtct tttatcatct
    26581 atagggatgc ctaattcatt gcaaaataca taattattat ttatatataa ttctccagcc
    26641 tttaatatat ctgtattttg atttacttta tgctctttca atttatttaa aacatctttt
    26701 ggaataggta cagttctgta agaatttgat gtctttggcc cttgctctaa tactttaagc
    26761 tctctatttc cagttttatc tataaaatat gttctttgaa gagttctttt aactgttaaa
    26821 ttagactttt taaaatcaat atcaaaccat ttaagtccta ataattctcc taatctaagt
    26881 ccagtaccaa gagcaagtaa aaataatacc tctaatttat gcccatctat agcttttata
    26941 aaactctttt gttgttcaag agtcaatatt tcaagtttgt tttctttttt ctcaactggt
    27001 atatttacca tagtacaata gttacgttgt ataagacctt gtttttcagc ttctgataag
    27061 caggttttca gtttagtgtt tatttgcctt atagtaggta tacttttatt ggaatcaagc
    27121 aatctattgt aatatttttg tatgtgagat actcttaagt actttaattt aacattgcct
    27181 aaatcagtat ctttaatata attacgatag atgctttcat atctttcaaa tgacttgggt
    27241 tttaaatctt ttattctata ttcaaataac caattgtaaa accaatgctc taaagttatt
    27301 ttatcatctg aaatatcaga gcttaaataa tattgttttt tataagcatc taatttatct
    27361 ttaacttcct tttgagtctt accataaaat tcttttctca gtggtttacc atcttcatta
    27421 tagccaatca ttatacggga acgccaacca tctttatatt ttccgataga gccttctcca
    27481 ttagctcttt tagttgccat ttttaaacag ctccttatat gatttatagt tatatccatc
    27541 aaagaatgta atacatttct ctaataagaa ttttataact tcatcagctt ctagtgtttc
    27601 atagaagttt agcattaatg tgttgtactc ttgtttatgt ttagctggta ttgatagaac
    27661 tcctatatca ttatttataa gtattaggtt tgaggtaagt ctagcagttc ttttgttgcc
    27721 atcatagaag aattggcaat aggacaacca taaatttatt attatagcct tttctaatgg
    27781 gttagttatt ttatttatga tatttatgtc atttacaaat aaatcattta atagagtggc
    27841 ttctatgcat tcatattgag tagtaccagc tatacctata ttaccatttc tgaaatctcc
    27901 aacgattaga gcttcatctt ttgcaactat tttatgtata gagcaaattg tatctttatt
    27961 taaagataag ttttctttgt tacttaattt tattacataa tcccatgatg attttatatt
    28021 tagtatttga ttttggtcac ttaatttatg tccgcctacg gttataccat caagtaatgt
    28081 ttgtacttct gggaatgtga aggggttatt ttctaggtta cccatatcat atacaaattc
    28141 acttatcatt cttctaatgt atgttaaagt atatttttta tctccatgag gtatattagt
    28201 agggaattta tgtgtgtatt ttggtatata tgatttattc atgattttag ctcctttcat
    28261 atctaatttt tatttattaa ctatgaatgt ataaaagtta ataggtaaac tcatattttg
    28321 aaaatgtgca atactaatat tcttcatcct catcttcaat aagaccatta gagttttctt
    28381 gtataaaatt ttcaacaaga ccatttatca cccaatttag atttttggag aagtctttga
    28441 agtcagagaa gtttaggtta attggtttta ttgtatctgc attatctgta atttcaaact
    28501 tttttttata gtctgttttt atatcataac cataattttc taatatgtga attactaaat
    28561 ccaactcttt atcaaatact tttaaattaa tattattatt tgttaaagta tctaaatcat
    28621 tttcttcaac aatgagttta tttatagcaa ttgataaagc agtagctatt tttcttatca
    28681 tatctaaact aggcattctt tgattttgct catatttagc tatagcatga actgaacaac
    28741 caatcttgtt ggctagctca tcccttgaca tatttatcga ttttctatat tgtttaatct
    28801 tttctccaat tgtattattc atcataattt caccttaaat atatcatcaa acaatgattg
    28861 tacttctaaa catgtaaagg agttattttc tagattatcc catatcatat actaaattac
    28921 tcataactct cttagtgtat gttagagtat attttttatc tccatgaaat aaattagtag
    28981 gggatttata tgtgtatttt agcatatatg atttattcat aattgtaact ccattcatag
    29041 ttttttatca ttgctttaga tagtattgat attattttat attttagtta gtagtttttt
    29101 tatttcttta agtgtatttt caagcttttc atttttttcc tttagttcgt tattttcttg
    29161 taataattta aagtaatcat tatttttaat agtaatattt tctttttgag atattaattt
    29221 ttttagtcga atattacttc cattatctgt tgagtcacta aagtaatcat agattgtttc
    29281 tatactttct tctgatagac caatatctaa taattcatca attgattgtt ttgtaagaac
    29341 atcattttta ataatttctt ttatgtcatc aggatgtaat gaaaaatcta attcagtatt
    29401 agatatacaa tctgaaagta tccaattata aacttgattt tcatttagtt ctaatttttc
    29461 accaagttta taatattggt ctttatcaga ccaggcacct agcaataaac ttgaggtaat
    29521 tctaatatca tcttccataa gatttgaaat agcatttaaa aattcatcaa aagaatagta
    29581 ttcttctggg aataaagact gtaaaaggta taaaacatct tcattagtca ttacttcatt
    29641 ttcaatatca aaataaaaga tagtcttttc aattttcaaa gctttagcga gttttgataa
    29701 ggtatctata ctaggtattc ttttatcatt ttcataattt attagagcat ttcttgagat
    29761 gccactaatt tcagcaagtt gaatctgcgt tagctctttt tgttttctta tcttttttaa
    29821 gttttttcca atttgcaata ttatcacctc gtataaagta tatcccaaaa gtacacaaat
    29881 gagaacagaa aaataatata ttcttattaa cagtacacat atatcgacat tataattaaa
    29941 atgtaaagtt tacgaatgta aactagaaaa aaggaggaaa aagtatggga atcaatttaa
    30001 aaatatttag gattaaaaaa ggtctaaagc aacaagaact ggcagataga gttggtatat
    30061 caagatatta tttatcaaac ttggaaacag gtaaggctaa taatccaagc aatgatttga
    30121 tgattaaact atctagagct ttagatacaa cagtagaaga attatttttt agtaaggagg
    30181 attaaaatat gaaagagaat aataatttag aggttttaaa gacattacaa gccactttaa
    30241 acattattgt aaagaatgaa gaagaagcac aagaaaaaaa gcaaggatat aaaattattg
    30301 aaaatgcgaa aagaaataaa gctgagctta taacatgtaa agaagcatct aagctttatc
    30361 ctataggaga atcaaaattt aggcagttat gtcattctaa aaacaaagga ttcccttgta
    30421 tatggataaa taatcgagta tacataataa aaaataaatt agatgattgg tttattgaaa
    30481 atgcaaatgg tatcaagtta tagtcttaaa gtaggtgttt gcaattgagc aataaagggt
    30541 ggataaagct ttatagggag ttgttggata aatcaatttg gaaagatatt aaaccagaaa
    30601 gaaaggtaat attaataact ctattactta tggctagtca taaagaaaat catgttttta
    30661 tagataataa aaagataaaa ataaagtttg gacaatttat ttcttcatat agcaaaatag
    30721 ctgaaagatg tggtaaagga gttagttatc aaatggttag aagttgtttg ttggttttta
    30781 aaaatgctgg ttttctaaca tacgaaacaa caaacaagta tatagtaata actattgaaa
    30841 actgggagct ttatcaagag aatatagaaa atcaacaacc taatcaacag actattaaca
    30901 atcagtcaac aacaatcaag aatataaaga atgaaaataa tattatatat agtgaaatca
    30961 taagcaaatt taactcaact tgtattgaac tttcaaaggt caagaaacta acagatacaa
    31021 gaaagaggag aataaattca agaataaaag aatatgataa agaaactgta ttagaggtta
    31081 taaatatagt tagtaaaaca agttttctga atggaaataa taatacagga tggaaagcaa
    31141 attttgattg gataatgaat tcaagtaatt ttactaagat actagaggga aattataata
    31201 gcaaggaaat tgtcataaat aaagagacag gaatatataa tccagatgac tcacaattaa
    31261 agtggtaagg aggttatatt ataaataatt caaacaactt aattaaaaat acagaagcag
    31321 agcaatcaat taaattacac taagttagtt ataaatcttt catatatttg ttttttaagt
    31381 atctctaata tcgtttaaat tacactaagt tagttgcaga tataccagaa aatatatata
    31441 aaattatgcg taaactatat tgttatgagt acaaataata tttacctatt cattaaaaaa
    31501 cttaactaag aatttaattt atattattga agtatcaata attttggaaa gtagaaaatt
    31561 ataccccaat aataccccaa ctacaaaaat agacaataaa aaataaccag aaaaattgct
    31621 tcaacatcat gaccaaatag ccatatacct atacttataa aaaccaacaa aacaatcaaa
    31681 taaccactta taaattctcc tcggtctcca ccattggaat ccacgaaaac atattgattt
    31741 aatagttaat atgtttttta ttttgaaaaa tcatatataa tataaattaa tagtttattt
    31801 aaaaatttca gtatgagcac aaaattatat aattattggg aattagttat aataagtaat
    31861 ttctagtaag aatgatttgc aaaaaataat aatttaaata caaaaaacta aaggatagaa
    31921 gtcataaaat taacttttaa cctttagtta tataaataaa aaattagtta ttactaaatt
    31981 aaaattagat ttttaaagaa cccaatatct ctattatcca tatcaccaat taacatgctt
    32041 ctatcaagta ataaattata ctcctcacag ctagtttcag gcaataaagt acatgaatgg
    32101 catgctccta gatttaaaga atttctacct tgaccagtac tatcaataca tattgggtca
    32161 ttagaacacc aaagagcacg attaagagca ctatttaata tagatggtaa tgaatcatgc
    32221 ataccttgcc taactaatcc tcctaaagta ccttcagagt caccacttgc agtgtaaact
    32281 aaaattccag acataacttt ttcattttcg gaattattac aatatatacg ttccctaagt
    32341 gaagaggtag catatccaca aacaaaacta agttctctta taattaaatg agctaaagta
    32401 tgtagtaata agaatttagg tgtaattttt ctataagctt tgtcattaac attaatatct
    32461 ttattatatc tagaatttaa aatagatgca ttatcctgta ttttaggatt agatgaaatc
    32521 cagcttttta ccatatcatt atttatctct atgaaaatac cttcacctct aacctcagat
    32581 gcaggataaa aagatttttt acaatctcta gatcttaaac ttataacctt agtatcatta
    32641 cagctatcat ctatatcttc ttcaccaaat atattattat caggtggatt gactctacta
    32701 aacccagtta atgcccttac ttctctaagt ctttttacta acactatttt actgaagttt
    32761 ggaatatcat aatcagatag attttgttct tctattgtaa agtcattagt ttttttagat
    32821 ttagcatcta tatttccaat taaagcctca tattcttctt ctctatattg atttctagtt
    32881 gttgttgatg gtgaagaatc ttcaaaaggc aataaatctt tcaaaactat ggatacttta
    32941 tcagtatcaa aacctgtttc tttagcaata tcactggcaa agtcctcaaa atcctcatcc
    33001 ataaagcgtt ctaacttatt ctttttaata gcacgatcta agaatttctt aaatgtatca
    33061 taacctttac tagatagcac tttagaatta agagtatcag agtatggtgg tataataatt
    33121 gaactttcta tcttaggata atatacatta gaggcacctc tttgagaagc aaatgaatat
    33181 ttagtgcatt tatttacttt tttattatac caaggcgaat taccagagca tttaaacatt
    33241 tccttatatt cactaggtac accataatca ttagatttag aagattttaa acgcataaat
    33301 gcgcccttca tattagcttt agctccacag ctacattcaa gttctatacc ttctaatcct
    33361 aggttacttt ttccagtctt cattaatatt tgaggatttt cacaaatttc ttttcttcca
    33421 gatttatttc taaaatgaac ccattttacc catggaaaat catcaatatg accatgttca
    33481 caaatagtaa ttataccagt aggtactaat tgtttagtag acttttttgt gctacaagta
    33541 aggcaaatag gtattttcat aggtttatct ttatgagcat ttttataaag tttctcccaa
    33601 tcttctatag gcataaattt tctacatttt ggacaaaagt accatctagg aaacctaaca
    33661 aaaggaacag aagatctatc atctatagtt ggaggtgttc ttagttcatt aaccctcaat
    33721 gtagcctgaa gcctatcatc ttgtatttta attgtattag tccaataatt tggatgagca
    33781 gtcattaatg tttgatcaat aaaatctagc atagctcctg gtccaaaaac acttgtagct
    33841 tgatttattc ttaaattatg agttttatca tctaatttta tagacatatt aattttcctc
    33901 caattctata atttcaacag tacattgttt atcaacattt ctcatagaat ttaatgtttg
    33961 tttttcattt gtaataacat ccttatcata aggaattaaa agattattat atattttatt
    34021 atcaaattta ctagggcgct tataataatg caataaatta tctttatcag atatttgagc
    34081 tttatcatgc cataaatcca ttataatatc taattcagat gaaatctcag atttaaattc
    34141 atttactata ttatcatcag cattttgatt attttctcta aatatatcga tagatctatc
    34201 tattatgaag ttttttaaat cttctacacc atccatattt tttgaaaatc gacttgcaag
    34261 atcattagct tgaagtccta aaatatgtct aatcatactt attaatactg catgcatgcc
    34321 tctttctcta gctggttcag agaaaggtgt aatactagta ggttcaacaa atttatagaa
    34381 tgattgatga taactaaaga actgttcata atgagatcta tctcttgttt ttgtaggatt
    34441 atataatgta aatataagtc cttcattact tctaccaact ctactgctag cttgtatgta
    34501 ttcagatgtt aacttaggct gaccaactac taccattaaa tttaatctat caacatcaac
    34561 accaactgaa atcatattac tagctaatag agtatcgaca gttaaattat tagaagtaag
    34621 agtattagat agttcatcta aagttgtatt tatcttagta gaagtaagtc tactagtaag
    34681 ctctctttgt tcatttaggt tccttaatga ttgataaggg tgggctgaga ctcttttaca
    34741 taatctttcc atgttgtctt ttatatcgtc atttaaaagt gtgctacact tacctaattc
    34801 tctgatacta ttaaaataag atactagtgt ccaatattta tccaataaat tcaactctac
    34861 attctccatc attttaagtc tttggagtaa tgctgacata agtctaacct ctacagtaac
    34921 ttgagttttt ccagatggaa taacacctac atatagtcgg ccacgttttt tacttaaagg
    34981 catctcttta acaaagaaag agttactaga tgttaatcct ggaggtggaa actgagctac
    35041 attacgatta tatagatttt taacttgatt ttgtgctttt cttatagtag cagtagaagc
    35101 tataatctta ggttttatac ccttatagct acacatagca tcaagtgcag tttcatataa
    35161 acctaccata gtacctaaag gtccagaaat aagatgaagc tcatcttgaa ttattaactc
    35221 aggagataag ttgctattat catcatctaa agcaaaaaga ctagctactt ctgtagtcca
    35281 agttatcatt gcaaatttat caactgtacc aaataaaagt gttggagggt tattataaat
    35341 ctcctcatct acaacttgta taggtaacat atcttcaaat gaacaatctt cttcaggaca
    35401 gcataagtag aatttcttag gtctagattt aattctatag ccccaatcac caacagcttt
    35461 tttagaagtt ttatcccatt ctttaacaag ttttgttcca caccaaggac attttagtaa
    35521 ttggaattta ttatattttg attttaaatt atctaactca tattcactat ttatactaga
    35581 tctaaactta atgttattac ctgttaagtt attaagcatt tcttctgcct catcattaaa
    35641 gtttggagtt tgatcactcc caatccacaa accaatagaa atctcttttt tcccaagttc
    35701 agacttattt tcttttctaa taatttcaca ggcacaaatt aatatacttg ctcttatgaa
    35761 ttgttgtgca gccaatagcc ttagtgtata tctcattatg atagctgtac cgttaccatt
    35821 ttctttgttt cttattcttc ttaagaagat agtaaaagca gatagaccta agtaggcctc
    35881 cgttttacct ccaccagtag ggatccaaag aaggtcaact aaatctctat gtttagagtc
    35941 aggattttct atcgaagata aacatgtaag tatataagca agctggaatg gtctccaagc
    36001 agaattatca tttgagtaat ctatatagtc aaggttatta gatccaggga gtctatccgt
    36061 aatatgtata gaatgacatc tttgcataag tatagctcta ttcattagag aaaatgctct
    36121 gtatacttca tcattagact taattaaatt tataccttct agcattctag acttagtatc
    36181 tctgcagttt tttatatgct catatgctac atctttaaaa acatcactaa gatcttttga
    36241 atcttcttct agatcatcta tccaaatatc ataagcatca acaaacttat aaagaaaata
    36301 tattttctta tctttactaa gatcagagat atctgataaa tttttcatag acagtaattc
    36361 tctagaaaca tcacttaatt catctacatt aaagtccaat ttaggtactt caaaatgagg
    36421 aataaactca gtacaaagtt ttattaaagc atcattttga atatcttgat ctatagctac
    36481 accatgacca gtagcaaaag tttttttatt tcggtaaagt aagtctaaag atatttcctc
    36541 agaatctaac tttttaaaag tatttactga tccagctgta aaaatatcta taaactctaa
    36601 atcattgtta tcttcagcta ataccattag ttcaggctgg aaaatagtat tattatattt
    36661 cttaggccca gattgactat taaccagcat acaagtaata ctaacaaagt catttgaata
    36721 aattctttta gataaaacta tatctaaatc tttagatata ggttttttaa tatagttttt
    36781 atccatatct attgatacta ttaagttttc atgtggaaca cgaacataac caccagtctt
    36841 attctcatca tcagggcatt ggttagctaa cttgtataaa acaaatttag cttcagcatt
    36901 atcaagtaaa tcatgctttt ttagtaaatt ataaaccttc tcagatgtta gtttttgctt
    36961 aagatatagg aatgatcccc taagttctac atattcatta attgtattgc tagaatagaa
    37021 gtcgtcacca gtatatttaa catgacagtc tgtatataaa gcatttctat aagtagcata
    37081 atttaccctg aaatttatta cttctgcatc tttttttagg aaaaaagtca tacccataga
    37141 agaaggtaaa gtttcattag acatacttat agctctatct agttcatttt gtgtatcatc
    37201 tgatgtaaat acattatctt caccatcata ttcagatgta ttacttacat caatattgtt
    37261 attaagtgga tataaaatac ctgttgaata acgctctatt ggactatctg ttattatttc
    37321 atattttata ttttcacaaa gatcttccga accaggtcca agaagttctt ttcttacaag
    37381 atctagggtt ttatctctta gttcactaca attcatattt acctcctatt tatttaataa
    37441 acactatata agtctaaaac tttgttaaca aggtggggtg acagatactt atcacaactg
    37501 tgtatttctc gtatttgtac aggtgtaaca taatcatttg tattcccaag catacttaaa
    37561 acaactgcag acacttcatc tttaattata tctgatttac tgctaaagaa attatcagat
    37621 acaaatgtat ctatagattt ttttatttta gtgtgcaaag agcgtatact tttagtagca
    37681 tcatatacct cggtatgatc taatttagaa tctataactt taaatatctt ttcgaaagtt
    37741 tttaaatata taggacctat taatctttta tttgttaccc agtttttgat tgttatagga
    37801 ttaatctttt cacctaaaac agctaaactg tttgatacat cattataatt atatttacta
    37861 taagatatat agtttttaag ttctgatttc catgaattag ttaatttata atcatcaaga
    37921 taatgagatg gcaataaatt aagttctaat agcttttgta taacattaat aactaattca
    37981 ccctcttcat ttaagtaatc atcaacaaat aaaaaccagt cattaacttt agcctctgaa
    38041 agtttctttt tcctaacact ttttttatcc caatctattg aataggctat tgcctttttt
    38101 gtacagaata tatactcatt attatcagaa atcatgaatg atgtaacatg ttctttttta
    38161 gagttgtaaa tcccttgatt tatagataga gataatataa tttcatttaa atttatatca
    38221 aatttataat tagatatata ttcatccata gaatcatcat cagaaatagg actatcggta
    38281 gaataagctt ctaatttatt ggtttcataa gttggtttaa aaggttttat atcaagtaag
    38341 ttatatattt tattattttt ttcaatttta tttcttgcag aatttatttg attcatatag
    38401 taattatatt tggataattc actattatat aaatacagtg taatatttat aatca
//
LOCUS       DAJMZY010000028        38222 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.028, whole genome shotgun sequence.
ACCESSION   DAJMZY010000028 DAJMZY010000000
VERSION     DAJMZY010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 38222)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38222)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38222
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.028"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            complement(576..1730)
                     /gene="nagA"
                     /locus_tag="OE968_001417"
     CDS             complement(576..1730)
                     /gene="nagA"
                     /locus_tag="OE968_001417"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HCP7218701.1"
                     /translation="MKSFIYADKFFMKHGIKEKGYLSIINGKFGEFQQERPNVTDNVI
                     DFSGKYIAPGLVDTHIHGLLGADVMDNTFEAINTISKGLLKYGVTSFLPTTLTDSVDT
                     LSDSVENISNSFNRVEGAKIQGIYLEGPFFTEKYKGAQNEKYFKDPDINILKLWQKKS
                     KNLIRKIAIAPERKGSIELTRYATKNNISVSLGHSSATFEQVKQVVNSGAKVFVHTYN
                     GMSPLNHREPGMVGAAMVLKDTYAELICDGHHVSPIAVKIMMDAKSSNNIALITDCMR
                     AGAMEDGKYTLGKFNVNVKNSVARLNSGSLAGSVLTMDKAVRNIVDWNIATLEDAIKM
                     ATYIPALSCNIDNVCGSIHQGMEADFIVTDKDFNIYETYISGICKYKVNK"
     gene            complement(1813..2538)
                     /locus_tag="OE968_001418"
     CDS             complement(1813..2538)
                     /locus_tag="OE968_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCP7218702.1"
                     /translation="MIKRNDKRPIYDQLVEILRTKIENEMEPNDRMLSERKICDEYGV
                     SRTTVRLAMAELEHMGYIYKRHGKGTFVAALSQNSQNLMESYSFTDYMRTQGKKPGTK
                     VLSFEVVESTKYFSEKLGITPGEKMIKIMRLRLADDLPMMLERTYLPMKEFIGLTKEK
                     IEQKPLYEIFREDYGEIIKVADEEFSAGIISDKEAKLLEVPGDSPCLKLLRTTYNDDN
                     IVIEFTLSVARSDKFVYRVRHVR"
     gene            2805..3734
                     /gene="pfkB"
                     /locus_tag="OE968_001419"
     CDS             2805..3734
                     /gene="pfkB"
                     /locus_tag="OE968_001419"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HCP7218703.1"
                     /translation="MITVITFNPSIDRMYRVNNINIGEVQRVVSKNATAGGKGLNVSK
                     VCKILKENPLAMGFLGGFNGEFIKNELRKLDIQNKFTKIEQETRNCLNIIEDNKVSTE
                     FLEKGPIVEKSDLERFENDIEEVLKNTKILVASGSYCENMPIDYYEKIGNICRANNIK
                     FILDTSGEALKIALKSKPYLIKPNIDEIRHLLGINIESREEIILSGKKLIEMGAENVC
                     ISLGKDGMVYLNEDNVYYVKVPVVKCINTVGSGDSTVAGFSVGILRGYKIENLLKFAN
                     ACGISNALNMETGFVDLGEIDKYQDLVEVKKLS"
     gene            complement(3863..4780)
                     /locus_tag="OE968_001420"
     CDS             complement(3863..4780)
                     /locus_tag="OE968_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HCP7218704.1"
                     /translation="MKNIKMGMIGLGSIAQKAYLPILTKSERFEFVGAFTPNKVKREK
                     VCSDYRIMQFDSIESLAKKCDCIFLHSSTETHYEIIKILLNLGVHVYVDKPLASTVSQ
                     GEELIELSTKKNLNLMVGFNRRFCPMYKEIKNNATEIVSINICKHGLNSLRNVKFDST
                     LIDDYIHVIDTALWLANEDVEISGEDLFLTDNKNLIFVSHKLKGKNFSINTSMHRDSG
                     TKLEQVEILSKGKIQRVKNLNVLEIEEGGNLTLKQSGAWVNILKQKGFEDISNHFIDC
                     IENNIKPAISGEECIKAQRLLEKIINSVK"
     gene            5250..6419
                     /locus_tag="OE968_001421"
     CDS             5250..6419
                     /locus_tag="OE968_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HCP7218705.1"
                     /translation="MKMFKLEEQKLKDLGAIITTNEIKQQPELWLETYEIYKSNKEKL
                     SRFIDTISNNHGQFRVIFTGAGTSAYIGNSILPYLKNKNDIRKYIFEAIPTTDIVSNP
                     YDYLKKDIPTLLISFARSGNSPESLAALNLGNKIVDNFYHLAITCNPEGELAKMTKND
                     ENNYLLLMPSKSNDEGFAMTGSFSCMMLSAMLIFDSLEDDVEKSYINAIVEMGRNVID
                     RKDEIHELINKDFDRVVYLGSGGLGGLTQEAQLKLLELTAGKISTVYDSPMGFRHGPK
                     SFIDENTLVFEFVSNCLYTRKYDLDVLEEIKRDKIAKFTCAVSVENENNFSGTKFEFK
                     EKYNKLPDVYLAMPYILFAQTIALFVSVKVGNKPDTPSATGTVNRVVKGVTIYEY"
     gene            6468..7319
                     /gene="gatY"
                     /locus_tag="OE968_001422"
     CDS             6468..7319
                     /gene="gatY"
                     /locus_tag="OE968_001422"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase subunit GatY"
                     /protein_id="HCP7218706.1"
                     /translation="MALVTTTSMLKKAQDEGYAVGAFNVENMEMVIAVIEAAEELNSP
                     VILQTTPSTVKYAGLDYYLANAKVAAERVKIPVAMHLDHGSSFDLAMKALRSGYTSIM
                     IDGSHESFENNISISKSVVKACSPSLIPVEAELGKVGGKEDDLDGGNSNDYTNPKEAK
                     EFVDRTGISSLAIAIGTAHGLYKGEPKIDLDRLSEIKNVVSIPLVLHGGSGIHDDIIK
                     EAIKRGIAKVNYATELRIAYSKGVKKVLDEDSEVIDPKKYGLAGLQSVKDFVKEKIKV
                     CGSVNRV"
     gene            7645..9546
                     /locus_tag="OE968_001423"
     CDS             7645..9546
                     /locus_tag="OE968_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HCP7218707.1"
                     /translation="MRERIILETLKNSSGYLNIDYFADKLGVSTRTIRNEIKKIETIK
                     ECNGFKLEYKSKLGYILNIKDQDKFEHYLRNLPSDLVENPEQRLESIIVELLVNEGYK
                     TIEQLSKKFLVSSSQIKNDLKKIDEKIKDTELKLERKAHYGIKIEGSIKEIQSILVDS
                     YFRGNRNITEYRNKFIDNLKLANIRSTIKNVLNEHDLEANLTELEEILAQIIILYIRV
                     SMRVAGNASDLKLYTEDLIIDKLLDKIFRDKKYNLNYDEKYYLKELIKLKTKDKKATI
                     KNIDKNKLQDIMFEFFREIDKKYNSNFLEDKEFFNLFYLHIACLIERIKKNHKIINPF
                     SVKISQQYPTVFNLSIQFSKIIENEYHIKISQDEIGFIATHIAVPFEKREEANFNKKY
                     KIAIICSSGGGSAFLINLRLKEIFPNAEIRNFSLLEEKAVIEFAPDLIFSITNLLFEI
                     NAPVILINEILDELDYLDIKESVRFADHIGNISSPKQYILGLFDKNHFRCIKDKAKYK
                     DILDSMSKCIVDEGACSPTYPKDVWERESYLSTIYTNGVAIPHPIEMTGNKNIISVAL
                     IQTDIIYENRVPKIIFMISLIKGNLELHKQISKYLSKIMANKDMVDMLNKSQSYEEFM
                     YKLKIYLGG"
     gene            9549..10592
                     /gene="ypdE"
                     /locus_tag="OE968_001424"
     CDS             9549..10592
                     /gene="ypdE"
                     /locus_tag="OE968_001424"
                     /EC_number="3.4.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HCP7218708.1"
                     /translation="MNIEFFKRLSEADGIASNEEEVRHVLLEELKAYSDKIICDGLGS
                     IIFSKIKDESAPNVMICAHMDEVGFMVRSIDKLGMIHLITIGGVKPLAQFVQKVRITT
                     KEGKKIPAVINATYNNGKAENIYADIGAYTEEDVYNLGINVGDMVTYTTSFEEFTLPD
                     RLVGKAFDDRIGCFVMGEVLKELRKENLNCNIHFAATSSEEVGIRGAKTSTQLINPDI
                     VFVIDVACAKNEFVRDYTNQKQIDKGVMLMHRDRTLVPSRKMIDYVMEIADKNNIPLQ
                     HDMFESGGTDGGEAHLVNEGKPCVVTCVPVRYGHCAFSIVSNKDLENIIRLYTQLILN
                     FDEEQYKHIRNFI"
     gene            10607..10912
                     /locus_tag="OE968_001425"
     CDS             10607..10912
                     /locus_tag="OE968_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HCP7218709.1"
                     /translation="MSTEVQIMELISTAGESKSKAFEALKKVKSKDFKGAKLLIEEAR
                     KIDIEAHRIQTELITQDLNEDVESPAMSLLMVHAQDHYMTSQLAKDLIEALIYCLDK"
     gene            11009..11344
                     /locus_tag="OE968_001426"
     CDS             11009..11344
                     /locus_tag="OE968_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCP7218710.1"
                     /translation="MKILLCCAGGFSTNMLMQNMKKVVKESAKLNEKDFEFTAIPADS
                     IESEVDDWDIVLIGPQIAHKIDFLKGILEPKNKPFAVIDKDVYGKMDGATVMKLALIT
                     YKKHQLAQG"
     gene            11376..12698
                     /locus_tag="OE968_001427"
     CDS             11376..12698
                     /locus_tag="OE968_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCP7218711.1"
                     /translation="MFSKFEAFMNRVFMPLAHKVDNQRHLGSIKAGMVAMTPFTILGS
                     IFAILPALPNMLGENNPISKFILNNSAILDLPVSLSIGLIGLYACMCIAFNLGNYYKL
                     YIPGCVALSTFSFLFLVASFTPDGALEIGNLGAKGLFTGMIAGLGSVELYNFCNKKNI
                     TIKMPENVPDFVSRSFELIPTTIIVCGTFIVARFISLKVFGELPPQILTQFLSPLVGS
                     MDNPWSVLALNFAICTIFFFGIHSSVFSPITRPIMITFIAENIAAMQAGETIPHFFTA
                     GASSAFFGFTGCGISIGCVIACMLSKNASYKKIGRVSLFPALFGINEPILFGAPIILN
                     PIMFIPHVFGGAIIGTLPMFFMHWGWLAKPVFDPPYVGVFLEGFLTNGDWHSILANAL
                     QLVLAVLLYWPFFKIMERQQNNKKQKEETKNIFSKEEEDLLDDLGLDF"
     gene            12708..13778
                     /locus_tag="OE968_001428"
     CDS             12708..13778
                     /locus_tag="OE968_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HCP7218712.1"
                     /translation="MNNTMERLVSLIYKRGVDALLIKAKNTKRYIGALSGSGVYVLVT
                     KDKNYQILDGRYIDEADKKTTGFIKRIVSQGSYIPTIIELLKELNIKKLAIENQAMSI
                     QEYLSLKNEGFEINLITNELWKLRAIKSKEEIELIKKACEITDEVFDEVISEIKKDMT
                     ELEVSALIQYHALKKGASGMSFETIVVSGERGAMPHGRPTNKKLKVNEAITIDFGVVY
                     QGYQSDMTRTISIGKPPKIIKEIYDVVLEAQLSAIESIKEGTRASDVDKVARKIIDKH
                     GFGEYFNHGLGHGIGLGDGEVPTLNPNSEDILVEGMVMSCEPGIYIPNVGGVRIEDDI
                     VIIDGKGVPLNKTSKEFIILGE"
     gene            13783..14970
                     /locus_tag="OE968_001429"
     CDS             13783..14970
                     /locus_tag="OE968_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HCP7218713.1"
                     /translation="MKYNFNKVLNRKEGNCRKWSNHVIKEKFGLNEDAIPMDLADIDF
                     ECAPAIKESILKRASVGDYSYTFIGDDFYDAIINWNKRRFDVYIEKDWIKLTFGTVST
                     LHYIVQAYTKEGEGVLINTPAYDPFAEAVVNNNRKLCCSSLKLDNNRYYLDLEDMENQ
                     MKYENIRLLIFCSPQNPSGRIWTKEELYQVSELCLKYNVILVSDEIHRDIIFKDYRFV
                     SLWNAHPEIYKNSIICVSPNKGFNLGGLKTSYVLIRDVKIRETLLERLKSNSITSPNV
                     FAIPAIVAAYNESEEWLDAMTSYVEENFEIVYDFFETNIPKAKVMKSDSSFLAWIDVR
                     EVFRNEEESKEFFRHANLTMVVGSYFVKDGDGFIRINVGCPRETLNEALNRIKKTYIS
                     MYC"
     gene            complement(15167..16039)
                     /locus_tag="OE968_001430"
     CDS             complement(15167..16039)
                     /locus_tag="OE968_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HCP7218714.1"
                     /translation="MNILQNENLIIESSSFGAELTKIFSKKYDKNILWDGNKKYWGRQ
                     SPILFPIVGKLFDNETIIEENLYSMTQHGFARDMDFEIVDKGDTFVTYKLTDNESTLK
                     KYPYSFELIINYTLNDNSIEVEWIVKNTDSKDIFFSIGGHPAFNLPFYEQNDFSKHYL
                     EFKSKNDVEKINLNGSFTDDIIPIGKLKNLQLNPEVFKNDALIYTNIDEVSICNNDGS
                     KYVTISMEDFPLVGIWTPYYSETNSTAPFLCIEPWYGLADSINSNKIYKDKKFINKLS
                     KGKVFTASYNINIH"
     gene            complement(16433..16624)
                     /locus_tag="OE968_001431"
     CDS             complement(16433..16624)
                     /locus_tag="OE968_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218715.1"
                     /translation="MDDFSKLKSLYEDGYRCIYHDCVDNNYTIYLKNFYTEGSETIEL
                     SSESDFSQFKDYIDGLRMS"
     gene            16844..17890
                     /gene="cobT"
                     /locus_tag="OE968_001432"
     CDS             16844..17890
                     /gene="cobT"
                     /locus_tag="OE968_001432"
                     /EC_number="2.4.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide--dimethylbenzimidazole
                     phosphoribosyltransferase"
                     /protein_id="HCP7218716.1"
                     /translation="MSLLESISKNIYSLDNSSIEKTKQRLDRLIHPTGSLGKIEDICM
                     QLAGIFGNENFDTSKKVIIAFAGDHGVYEEGVAPDPQNITKLQFPNFSKGLCGVGVIS
                     KFVGADVVAVDVGINCDEKLDGVLDYKIRKGTSNMAKGPAMSKQEAIRCLEIGIEIAE
                     QCIEKDYKVIGIGEMGIANTTPSTAIISVISGCDPLEVTGIGAGLKKERLKHKAEVIR
                     KAIEINNPNPTDGVDILSKVGGFEIGSMAGVILGCSANRIPVVIDGFISYAAALIAYK
                     INPKTREYMIASHLSAESGTKRALDILKLDPLLNMDMRLGEGSGAALAFDIIEASNYT
                     YKNMATFDEIDMGR"
     gene            17922..18482
                     /gene="cobU"
                     /locus_tag="OE968_001433"
     CDS             17922..18482
                     /gene="cobU"
                     /locus_tag="OE968_001433"
                     /EC_number="2.7.1.156"
                     /EC_number="2.7.7.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional adenosylcobinamide
                     kinase/adenosylcobinamide-phosphate guanylyltransferase"
                     /protein_id="HCP7218717.1"
                     /translation="MSKIILVTGGARSGKSNFAEKLCFDRNNNTAYIATSIPFDDEMK
                     DRVKKHQENRPRNWNTYEIYEDIYSIIKEIYKEHETVILDCVTLLVNNLMFEHNLNIE
                     ESSQEEINKLEQYIKEQVVKLIEEIEKTNLYFVFVTNELGMGIVPGNKLSRIYADIVG
                     RINQYIASKSNEVYFVVSGIAMKIKE"
     gene            18492..19265
                     /gene="cobS"
                     /locus_tag="OE968_001434"
     CDS             18492..19265
                     /gene="cobS"
                     /locus_tag="OE968_001434"
                     /EC_number="2.7.8.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobinamide-GDP ribazoletransferase"
                     /protein_id="HCP7218718.1"
                     /translation="MKRFILILQFLTRIPIKLNVGFDDEFYKSIVYFPLVGFVIGILS
                     YLIGWISMLLFEPFIASIIITLAGVLITGGLHIDGLGDTFDAIYSYRDKEKMLEIMKD
                     SRLGTNSLLAIMFVLLLKVGFVYDIISNNSLWVIIFMPMIARLGVMLLTYKTVTPREK
                     GMGNLFIGKLTTSMLITAIIYTLLIVALITKFIFLLPNIVLIKVLGSIIVVFVFIILF
                     KKHIYKKIDGVTGDILGCGIELSELVYLIYIYLLIFMFF"
     gene            19285..19899
                     /locus_tag="OE968_001435"
     CDS             19285..19899
                     /locus_tag="OE968_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HCP7218719.1"
                     /translation="MIRLILIRHALTNDNKKGRLSGHINSCISEEGKLQINKITRYLS
                     NENIDKVYTTPSTRTKDTVEKISKLKLLEIEEKEALREISFGDFEGRTFEEIKIKYPN
                     EFEKMIKEGNNYRYPNGESLIDSYKRVAKEIDNIILENDSNLDTKTILICSHAGTIRN
                     IITHLISGSYKYHWNFKIDNASITVLEIDGGFAVIDKMNFTDFI"
     regulatory      19966..20145
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            20275..21774
                     /locus_tag="OE968_001436"
     CDS             20275..21774
                     /locus_tag="OE968_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobyric acid synthase"
                     /protein_id="HCP7218720.1"
                     /translation="MLQGTASNVGKSVLVAGLCRIFKQDGYTVAPFKSQNMALNSFIT
                     KEGLEMGRAQVFQAEAAKIEPIADMNPVLLKPSGNNKSQVIVRGKVVGEMPSSKYHDY
                     KLELVDVLKETFNSLNSRYDIVVMEGAGSNAEINLKDRDISNMGMAEIADAPVIIVGD
                     IDRGGVFASLAGTMLLLNEDEKRRVKGVIINKFRGKKELLQDGVKMLEDIIKVPVIGV
                     VPYTDIKIEDEDSVTTRFKKKMNKSDIHIEIIRTPHMSNFTDFNIFETQEDVSIRYVD
                     YGESLGNPDILIIPGTKSTIDDLTYIRKSGLESQIKNLHSQGKLIFGICGGYQMLGKK
                     LKDPYHVESEIEEVDGIGLLDTETTFEKEKTTTQVEATIVECISEYMNNLKGKKVKGY
                     EIHMGITKRGNDVRSLDLITKKLDKEVNYTEGSVNKEGNVIGTYLHGIFDEISFTRAI
                     LNNIRKKKGLGELESKVNSFNEFKDKEYDKLADFLREHLDIEKIYEIMK"
     gene            21813..23189
                     /locus_tag="OE968_001437"
     CDS             21813..23189
                     /locus_tag="OE968_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobyrinate a,c-diamide synthase"
                     /protein_id="HCP7218721.1"
                     /translation="MKKILIAGTNSGVGKTTISLGIMQALVKRNMKVQPYKVGPDYID
                     PSYHTFITGRHSRNLDSYMLDDEKIKYIVNKSSKDADISVIEGVMGLYDGFGIDLDNC
                     TSSHTSKVLKSPVILVINGKSMAASSAAMVLGYKELDKDVNIKGVIVNNVKTNSHYQI
                     IKSSIEKYCNVEVLGYFPPNNKFSLESRHLGLVPSVEMKSLREKFYTLADEIEHYIDI
                     DRIIEISESDEFESDFDFQTLIENNKIKEHVNNKSIAIAYDKAFNFYYRENIELLEEL
                     GLEINYFSPLEDVSVPNADYIYIGGGFPEIFGKELEANESMRTSILEAHNNNIPIYAE
                     CGGLMYLGEKLLNQEEQEFNMVGIFSGISKMTSSLKRFGYCIGVAKENTLLSKKGESI
                     KGHEFHHSIFESDEKCVYSMRKERDGNIVEEWDGGYSKGNTLATYLHTHFYNNLNCIE
                     NFLKKGNE"
     gene            23190..24161
                     /locus_tag="OE968_001438"
     CDS             23190..24161
                     /locus_tag="OE968_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin biosynthesis protein"
                     /protein_id="HCP7218722.1"
                     /translation="MSILSIYIGYVTDLIVGDPYSFPHPVRFIGKLINFTQGIIRKVS
                     KNDRQLKLGGFILWFITVGITYLTTYAIVKLFSFNILLSIVVNSFIIYTTLATKCLKD
                     EALKIYNVLKTEDIEKSRIQLSYIVGRDTTNLSEPEIIRATVETVAENTVDGIIAPMF
                     YAFIGGAPLAMAYKAINTLDSTVGYKNKKYKDIGFASAKIDDIANYIPARISVILMTI
                     GSFFLNYNYRNCFKISIRDRKNHKSPNCAFSEGAVSGALGIQLGGTNVYFGEKVYKPT
                     IGDKLREIDKEDIIKTNKIMYASSFVSMLVFTLIYVLCRMILINLII"
     gene            24193..25263
                     /locus_tag="OE968_001439"
     CDS             24193..25263
                     /locus_tag="OE968_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HCP7218723.1"
                     /translation="MKDLGHGANVDEMARLYGKNPKEIIDFSSNINPNVLPNLERYIL
                     KGLEECRNYPDINYTNLRENISKYIDINPDFIIPGNGATEVIYLLMKSIKKKLAIINP
                     TFSEYRRSAELNNLDIIDLELDLENNFKLNIDIIKENIKRFDSLFICNPNNPSGNVQD
                     LKELVHLLDKHNKVLIIDETFMEFVEDESKYSLVKYIESNKNIFIIKAVTKFFGMPGL
                     RLGYGLTSNTEIMNKIYEHKEPWTINSFADILSNFIFEDKEYIKNSKEYYIEEREYML
                     QELRNIRNIKVYDTDANFILIKIYKKTTKELKKDLFKQGNILVRDASNFIGLDDSFIR
                     VAIKSHEDNKILIENMKNLLGD"
     gene            25265..26152
                     /locus_tag="OE968_001440"
     CDS             25265..26152
                     /locus_tag="OE968_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin biosynthesis protein"
                     /protein_id="HCP7218724.1"
                     /translation="MKSYGICPASCGEFVQGIIDDEEYLCSYAIDMYSKVYIEEKLVD
                     INLGRYKSRLAIEKVFEKFNLPKKYTKNISLNINSKIPVGKGMASSTADIGATIKATL
                     SLIDKDLSSEEISKLAAEIEPTDSIFIDKNSIFNPLNGTVIKYLGNLTNAKVVILEPN
                     KVLDTMKIRLRQDYNKLKVENKEVIKKSFALLEEGLKKNNLSLVGEACTLSSLANENI
                     EKKEYLNEIIKISKKYGAYGVNIAHSGTVVGILIDKFMNDKKMIDALCESNINSVYNK
                     IYTQNIINGGIKGEIEWNT"
     gene            26140..26772
                     /locus_tag="OE968_001441"
     CDS             26140..26772
                     /locus_tag="OE968_001441"
                     /EC_number="5.4.99.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003724727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-8 methylmutase"
                     /protein_id="HCP7218725.1"
                     /translation="MEYIKNPMKIEEKSFELIQEIIDEIRPDYKFKNNIEEKIIKRAI
                     HTTADFDYLDILKISEEAVDSIIDALKNNASIYTDTNMALSGINKRKLESLGCKYKCL
                     VADDETVKLAKEKGITRSMAAVEIAAKEEGRKIFVLGNAPTALYKVMEMKSEGRLDLD
                     AVIGVPVGFVGAQESKDEVEKTDIPYIISKGRKGGSNLAAAIVNAILYTM"
     gene            26781..28007
                     /locus_tag="OE968_001442"
     CDS             26781..28007
                     /locus_tag="OE968_001442"
                     /EC_number="2.1.1.195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-5B (C(1))-methyltransferase"
                     /protein_id="HCP7218726.1"
                     /translation="MEEYVYIDGKKYRRGYTTGSCATGASKAAVYMLITKNRINTINI
                     DTPKGIPLLLKVDNINISDTFVECSIKKDGGDDIDATHTMDIYARAEIVAKNDKNKGY
                     LTLKDIDSLSTNSECKSELYKFIRVYGGTGIGVVTKKGLSVDVGKPAINPTPLKMINH
                     EIRKLIGDNFESILGNDKVLKITIFAPQGETVAKKTFNPRLGIVGGISIIGTTGIVEP
                     MSDDGWKKSLSIELQMKKEQGLDKIILVPGNHGEQFIREKLNLDIKYVVRVSNFIGYM
                     IKEAQRIGYKKILMAGHIGKFIKVSAGIFNTHSKVADARSEILVANLALMGARYEFLN
                     KINQCVTTEEAVELINNSEYREVYNILSNKCRERVKQYLNEDSDDIDVEVIIFSMDKS
                     LLGKSDNTDDLVEVFI"
     gene            28004..28612
                     /locus_tag="OE968_001443"
     CDS             28004..28612
                     /locus_tag="OE968_001443"
                     /EC_number="2.1.1.289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-7 (C(5))-methyltransferase"
                     /protein_id="HCP7218727.1"
                     /translation="MINIIGLGPGNLDYITKKGENLISTSDVLIGGKRNLESIKNFEG
                     EKIVLDSNLREIIEYINNNKEKQISIIASGDPLIYGIGRYLSKNIDNKMLNMVSGISS
                     LQYIFSKIYVDMNDVYITSSHGKVPDFDYILSHKKVCMVTDSKIGPKQISREIIDRNL
                     NKIIVVGENLSYDNEKITIAKPEEIIRMDNFDMNVVVILDEE"
     gene            28602..29177
                     /locus_tag="OE968_001444"
     CDS             28602..29177
                     /locus_tag="OE968_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decarboxylating cobalt-precorrin-6B
                     (C(15))-methyltransferase"
                     /protein_id="HCP7218728.1"
                     /translation="MRNSEFITGKVPITKEEVRAISISKLNLVNAKNLIDIGAGTGSV
                     SVEAAYNYPNLKVISIEKNDDAIELIEKNKKKFNLKNIEVIKGYAPINLGLNVKVESI
                     FLGGTGNNLEEIIEWSKKNLVTGGRLVANFIIIDTFNQTLKLLKKHGFKEIDVCVLNV
                     SKLEKLGKGEYFKPLNPIYIISCEKGENDDE"
     gene            29170..29922
                     /locus_tag="OE968_001445"
     CDS             29170..29922
                     /locus_tag="OE968_001445"
                     /EC_number="2.1.1.271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-4 methyltransferase"
                     /protein_id="HCP7218729.1"
                     /translation="MNKVHFVGAGPGDKELITLKGYKLLSNADVVIYAGSLVNPELLE
                     YCKEDCQIHNSAHMDLQEIIDVMREGIENNKSVVRLQTGDFSIYGSIREQVEDLNKLN
                     IDYDCTPGVSSFLGAASSLGVEYTVPEISQSVIITRMEGRTPVPEKESIQSYAKHQTS
                     MVIFLSVQEIEKVVSKLLEGGYPKDTPIAVIYKATWADEKIVKGTLSDIAVKVKENNI
                     NKTALIMVGRFLGEEYNNSKLYDKDFKHEYRG"
     gene            29906..31027
                     /gene="cbiG"
                     /locus_tag="OE968_001446"
     CDS             29906..31027
                     /gene="cbiG"
                     /locus_tag="OE968_001446"
                     /EC_number="3.7.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin 5A hydrolase"
                     /protein_id="HCP7218730.1"
                     /translation="MNIEGNIAIICITENGKKLALKINSLVNNCVIYHVKNKKSNLVV
                     EETCVHTVQKKLSDFVGEIFSKFDYIVFIMATGIVVRSIAPYIISKFSDPAILVMDEK
                     GKNVISLLSGHIGGANSLTQYISSLIDANPVITTATDINQKASLDMIAKKLNAHIDNF
                     RESVKEVNSMLVNNKCVGLYIDEGYQVDTRGFKLIESKDELRDSFSNTYIEKLVVVSN
                     KINCIEDIENLNLDNKFEHCYSTKKIIKVIPRDIVIGIGCRRNTDSELMYNSLEEFLN
                     KQNIDIRAINTVGSIELKKDEKAIIELSKILKVPFKTFSVDEISKVDNLFDKSDFVKK
                     NVGVYSVAEPVAYLLSKGNLLVEKHKYKGITFSVGRIKI"
     gene            31024..31749
                     /gene="cobJ"
                     /locus_tag="OE968_001447"
     CDS             31024..31749
                     /gene="cobJ"
                     /locus_tag="OE968_001447"
                     /EC_number="2.1.1.131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011701973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="precorrin-3B C(17)-methyltransferase"
                     /protein_id="HCP7218731.1"
                     /translation="MIYVVGIGPGSKDTMTLEAIKAIEDSEAIVGYKTYIKLIEEFIQ
                     DKEIIQNGMRQEVDRCKQAVEEAKKGKKVAVVSSGDAGIYGMAGLILELISKEDEDIK
                     VKVIPGVTASIGAAAILGAPIMHDFCHISLSDLMTPWEVIEKRLRLAAEADFVICLYN
                     PRSKGRSEHLSKAFKIMGEFKGGDTPVGVVKDVGREKEEKFVCTFENMDFEKVDMTTM
                     VIIGNKSTYINGELMITPRGYTV"
     gene            31746..32498
                     /gene="cobK"
                     /locus_tag="OE968_001448"
     CDS             31746..32498
                     /gene="cobK"
                     /locus_tag="OE968_001448"
                     /EC_number="1.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="precorrin-6A reductase"
                     /protein_id="HCP7218732.1"
                     /translation="MILILGGTSDSLSICDKINELKNQPYILSVTTDYGRELAQQHAE
                     NVILGKLGKEDMLKFIKDNNIVKIIDATHPYAVEVSKTAITCAKLLNIDYIRFERKSL
                     IEEIDYDNKFIVDTIEEACEIANKIGTNIFIGTGSKNLNRFIEEISDKNLVVRVLPTS
                     EVILSCEKLGLSADNIVAMKGPFSQYINEETYKHYNIDLVITKESGIAGGFLEKVNAC
                     KTFNIPVIIIKRESINYENVFNDINKIKDILV"
     gene            32517..33995
                     /locus_tag="OE968_001449"
     CDS             32517..33995
                     /locus_tag="OE968_001449"
                     /EC_number="2.1.1.151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-factor II C(20)-methyltransferase"
                     /protein_id="HCP7218733.1"
                     /translation="MKKALLVVSFGTSYHETREKTIDICEDKIKNSLKSHDFFRAYTS
                     NMIINKIKKRDGIEIDNPIQALDKIYEQGYDEVIIQTLHIICGEEFNKLKEQVDGYSS
                     KFKKIVLGRPLLTHIEDYQEAVEAIKHQIPHMESNEAVVFMGHGTLHESHSAYPALEY
                     MLRDNGINAYVGTVEGYPEIEHVIRRLKEGNIKTVNLMPFMLVAGDHAINDMAGDEED
                     SWKTILEENGFNVRVHLKGLGENSYIQDKFVRHAVKCAENAKFYGIGAGPGDGSLLTI
                     KAVNTLKKLDILYTPESKKGGDSLALSIVSEYLPESVEIKSRHFPMSFDGNEKSLAWD
                     NVAQEIISDVNDGKNVGFVTLGDPMIYSTYVYIMKRILGEVEVETIPGISSFSNIASN
                     QNFPLVMDKEALVVIPCTMEDDKIEYALQNYNSIVLMKVYKNFKEIIKKLEKYDLIEH
                     AILVSNSSQESENVFTDLKEAHLEDKISYFSTILVNKDNKIK"
     gene            34025..34930
                     /gene="hemC"
                     /locus_tag="OE968_001450"
     CDS             34025..34930
                     /gene="hemC"
                     /locus_tag="OE968_001450"
                     /EC_number="2.5.1.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylbilane synthase"
                     /protein_id="HCP7218734.1"
                     /translation="MNIVVGTRGSNLALIQTEWVINELKKKYPEISFEIKIIKTKGDL
                     IQNVSLDKIGDKGLFVKEIEQQLLDGKIDIAVHSMKDMPSYLADGLKFAHTPKREDPR
                     DVLILREGYKNLDDLPHGAVIGTGSKRRKFQLLKQRPDLNIVQVRGNVETRIRKIKDE
                     NMHGIVLAASGIIRANLQDKISSYLPVDVVIPAPAQGALAIEIRSNDSAIEGIVNSLK
                     DENTEIQILAERGFLDGVNGSCHIPMAAYCEIIQDKIHLTGLYGDSEGKKVVIKSIDG
                     DISSPRELGLKLAKLVLKEYENYEG"
     gene            34920..36419
                     /gene="cobA"
                     /locus_tag="OE968_001451"
     CDS             34920..36419
                     /gene="cobA"
                     /locus_tag="OE968_001451"
                     /EC_number="2.1.1.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen-III C-methyltransferase"
                     /protein_id="HCP7218735.1"
                     /translation="MKGKVYLVGAGPGDYKLMTLKGLECIRKSDVIVYDRLANSSYLR
                     EAKPDCELIYVGKASSNHILPQEDINRIIAEKAKEGKIVTRLKGGDPYVFGRGGEEAE
                     TLVDEGIEFEVVPGITSAIGGLCYAGIPITHRDHASSFHVITGHLKGDDSGELNWNAL
                     ANNKGTLVFLMGISNLEKISENLMKEGKDKDTPVALISWATRYNQRVVTSTLENVYET
                     AIKEEVKPPTLIVVGSVVGLREKLNFFESKPLFGKSIAVTRSRNQNSVLVEKIMDLGG
                     NPIEIPTIKVEKIQNNINLENEIKNINKYNYLILTSKNAVEIFFEKIYEMNFDLRILS
                     NLKVCAIGSATSNELKKRGIIADIVPKKFVAESLYEELAPILNDDDNILIPRAENARD
                     YLVDKLKAICEVTEVHIYRTVIDEEKKGEILDILNSNDIDYITFTSSSTVNNLVEIIG
                     KENIKILEKIKTLSIGPITTETINSLGIKLYKESATSTIDSLVDLIIKN"
     gene            36436..37401
                     /gene="hemB"
                     /locus_tag="OE968_001452"
     CDS             36436..37401
                     /gene="hemB"
                     /locus_tag="OE968_001452"
                     /EC_number="4.2.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porphobilinogen synthase"
                     /protein_id="HCP7218736.1"
                     /translation="MLRRPRRLRASKAIRNLVRETKVNVEDLIYPLFVVEGENIKEEI
                     KSLPDVYHLSIDMLEDEIKEISELGIEHIMLFGVPDEKDECASQAFNDNGIVQKAIRK
                     VKEINSDINVITDVCMCQYTSHGHCGILTDTGYVDNDKSLEYLAKISVSHAKAGADMV
                     APSDMMDGRIQAIREALDENGLENVGIMAYSVKYASNYYGPFREAAHSAPSFGDRKTY
                     QMDPANSNEAIIETELDILEGADILMVKPALSYLDIIRRVKDNFDLPLAAYNVSGEYS
                     MLKFAVKEGLLNEDVILESITSIKRAGADIIITYFAKDIAKLLKK"
     gene            37554..38132
                     /locus_tag="OE968_001453"
     CDS             37554..38132
                     /locus_tag="OE968_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional precorrin-2
                     dehydrogenase/sirohydrochlorin ferrochelatase"
                     /protein_id="HCP7218737.1"
                     /translation="MLYPINLKLDELDVVIIGGGEVAYRKCKNFLEFNKNVTIVSKQI
                     LNKFYDLKGNIKIIKDDYKEIYIKDASVIIAATNNRELNMEIGLYCKAKNKLVNVVDN
                     IEISNFTVPSYIKRGDLLISVSTGGKSPSLSSKIKKEIEERYTEDYEEYLNVLGDIRK
                     KVIKKYEDKSKRKDVLNMLVTLDLEELKKFDI"
BASE COUNT        15220 a         4027 c         6769 g        12206 t
ORIGIN      
        1 tgtattatga gttattattt ttaaatttta attacaaaag cagggtagtt ttaactactc
       61 tgctttatat ttaacataaa atatataaaa tcaacaaaat gattttagtc tatctattag
      121 atattcttcg ctctcaatgc ttagaacttt tagatatata caataagtgc tttcatttgt
      181 aaaaatttct atagtattat cttgtttatt tacacctaca atatctttaa aattgatatg
      241 atttttagta tttttacatt tgaaaatata tctgttatca attaaaatct catcattagt
      301 aattgaaata tagggtttat ctcatgcttt attaaaaatt tatatgtttg ttcaagataa
      361 aaacttacaa ataataatag aaaagttact ttaaatgtac atattatcga aaatattatc
      421 acaaaaatac ttataatata tatttgttta aaataacctc tatcgcaata gtttattaac
      481 gatatggaaa taaaagtgtt aaatcagatt ttggagaaat aactttaaat atttccagac
      541 tctttttaga cagcctccat aaccttatat tgaacctatt tattaacttt gtacttacat
      601 ataccactta tataagtttc gtatatatta aagtccttat ctgttactat aaaatctgcc
      661 tccatacctt gatgtatgga gccacaaaca ttatcaatat tacaacttaa agcagggata
      721 tatgtagcca tttttattgc atcttctaaa gtggctatgt tccaatcaac tatatttctc
      781 acagccttgt ccatagttaa tacacttcca gctaaactcc cactatttaa tcttgcaaca
      841 ctatttttta catttacatt aaacttacca agagtatatt ttccatcctc catagcacca
      901 gctctcatac aatctgtaat taaagctatg ttattactag acttagcatc catcattatt
      961 ttaacagcta ttgggcttac atgatgacca tcacaaatta attcagcata agtatctttt
     1021 agtaccatag cagccccaac cattccaggt tctctatgat ttaaaggact catcccatta
     1081 tatgtatgta caaacacttt agcacctgaa ttaacgactt gtttaacttg ctcaaatgta
     1141 gctgaactat gaccaagaga aactgatata ttatttttag ttgcatatct tgttaattct
     1201 attgaacctt tacgttctgg agcaattgct atttttctta ttaaattttt cgattttttt
     1261 tgccataatt ttaatatatt gatgtcaggg tctttaaaat atttttcatt ttgagcgccc
     1321 ttatattttt ctgtaaaaaa tggaccttct aaataaatcc cttgtatttt tgcaccctca
     1381 actcgattga agctattgct tatattttct acagaatcac ttagtgtatc tacagaatca
     1441 gttaaagttg taggtaggaa agatgttact ccatatttta ataagccttt tgaaattgtg
     1501 tttattgctt caaatgtatt gtccatgaca tctgcaccta aaagaccgtg aatgtgagta
     1561 tcaactaagc caggagcaat atatttacct gaaaaatcta taacattatc agtaacatta
     1621 ggtctttctt gttgaaattc accgaatttg ccattaatta tactaaggta acctttttct
     1681 ttgattccat gtttcataaa aaatttatct gcataaataa aacttttcaa aataacctcc
     1741 ttataattat attatcattg tggcattgac gcttataata tcattctgtt ttcttgaaag
     1801 ttatttaact tactatctta catgtcttac tctatataca aatttatcac ttctagcgac
     1861 actcaaagta aattcaataa ctatattgtc atcattatat gtggtacgaa gtaatttcag
     1921 acaaggtgaa tctcctggta cttccaataa cttagcttcc ttatccgaga ttattccagc
     1981 tgaaaattct tcatcagcaa ctttaataat ctcgccataa tcttctctaa atatttcata
     2041 taaaggtttt tgttcgattt tttcttttgt caatcctata aattctttca taggaagata
     2101 tgttctttca agcatcatag gaaggtcatc agcaagtctt aaacgcatta tttttatcat
     2161 tttttcacca ggagttatac ctaatttttc agagaaatac tttgtacttt ctactacctc
     2221 aaatgataat acctttgtac ctggcttttt tccttgtgtt ctcatataat ctgtaaaact
     2281 ataactttcc attaagtttt gagaattttg acttagtgca gcaacaaaag ttccttttcc
     2341 atgtcttttg tatatatatc ccatatgctc taactcagcc atagctagtc taactgtggt
     2401 tctacttact ccatattcat cacaaatttt tctttcggaa agcattctat cgtttggttc
     2461 catctcattt tcaatcttag ttcttaatat ctcaacaagc tggtcatata ttggtctttt
     2521 atcatttctt tttatcataa aaatatagtc ctttctaagt ggttattacc acaatttgat
     2581 tatagaatat agaattattt atgtcaatga ataaagttta atcaaaattc aataagtaag
     2641 gctattaatt tattataaaa ttatggtaca ttgacaaaac aagtaaaata atttatattc
     2701 aaattggtaa taaccacttt ggatatatta tatgaggtat tttttatttt acagattaat
     2761 ttattgttta gaaaagtaaa aattaataat gaggagaatc tagtatgatt acagtaataa
     2821 cattcaaccc atctatagat agaatgtata gagtgaataa tataaacata ggtgaggtgc
     2881 aaagggtagt aagtaagaat gcaactgctg gaggtaaagg attaaacgta tctaaggtat
     2941 gtaaaatttt aaaagaaaat cctttagcta tgggatttct aggcggattt aatggagaat
     3001 ttataaaaaa tgaacttaga aaactagata tacaaaataa atttacaaaa atagagcagg
     3061 aaactagaaa ttgcttaaac ataattgagg acaataaagt tagtacagaa tttttagaaa
     3121 aaggaccaat agtagaaaaa agcgatttag agagatttga aaatgatata gaggaagtac
     3181 taaaaaatac taaaatactg gtagcttctg gtagttattg tgagaatatg ccgatagact
     3241 attatgaaaa gataggaaat atatgtagag caaataatat aaagtttata ttagatacat
     3301 caggagaagc attaaaaata gctttaaaat caaaaccata tttaataaag ccaaatatag
     3361 atgaaataag acatttatta ggaataaata tagaatcaag agaggaaatt atcttgtcag
     3421 gaaaaaaact tattgaaatg ggtgcagaga atgtatgtat atctttagga aaagatggta
     3481 tggtgtattt aaacgaagat aacgtatatt atgtaaaagt accagttgta aagtgtataa
     3541 atactgtagg tagtggagat agcacagtgg ctggatttag tgtaggtatt ttaaggggtt
     3601 ataaaataga aaatttactt aaatttgcaa atgcttgtgg tataagtaat gctttaaata
     3661 tggaaactgg atttgtagat ttgggagaaa ttgataaata tcaagattta gttgaagtaa
     3721 aaaagttaag ttaaatacat ttaatgggaa tataataaat ttaatgttgt tgtaatagat
     3781 tttaatttta atataaaaga tatagtctta tataaaaata ggttagaaaa attcattttt
     3841 aacctatttt tataataaat atctatttta ctgaatttat aattttctct agtaatcttt
     3901 gagccttgat acactcttct ccactgatag ctggttttat attattttct atacaatcaa
     3961 taaaatgatt tgatatatcc tcaaaaccct tttgttttaa tatatttacc catgcaccac
     4021 tttgctttaa agttaggttt ccaccttctt ctatttccag tacattaaga ttcttaactc
     4081 tttgaatctt accctttgaa agaatttcaa cttgttctaa ctttgttcca gaatctctat
     4141 gcatagaggt gtttatagag aaatttttac ctttaagttt atgacttaca aatataagat
     4201 tcttattgtc tgttaaaaat aaatcctctc cactaatttc aacatcttca tttgctaacc
     4261 ataaagcagt gtcaataaca tgtatatagt catctataag agtactgtcg aatttaacat
     4321 ttcttaagga atttaatcca tgtttacata tattgataga tacaatttct gtagcattat
     4381 ttttaatttc tttgtacata ggacagaatc tacggttgaa tccaaccatt aaatttaagt
     4441 tttttttcgt acttaattcg ataagttctt ctccttgact tactgttgaa gcaagaggtt
     4501 tgtctacata tacatgaaca cctaaattta ataatatttt tataatttcg tagtgtgttt
     4561 ctgtagagct atgtagaaaa atacaatcac attttttagc tagggattca atagaatcga
     4621 attgcatgat tctataatca ctacagactt tttccctttt aactttattt ggagtaaaag
     4681 ctcctacaaa ctcaaatctc tcagacttag ttaatatagg taaatatgcc ttttgagcta
     4741 tggagccaag acctatcatt cccattttta tatttttcat aatactttct cctaaggttt
     4801 ttatatttac agaattgatt ataattcaga cacataaatt tgtaaacttt gtatcaaaaa
     4861 ataaatttaa agcttatata agtaaattag cgaaataaga aatattgata aagtaatttt
     4921 gtaggatatc tataaaattg attgatataa atattttatg tattgacaaa aaattcaaat
     4981 taatttatat ttggattagt ggtaattacc actttggtct gaacaagttt ttatcgtaaa
     5041 ataaaaatac taaagtatat agagtatgat tttattaaat ttttaaagat aaactataaa
     5101 attaattaaa atctatagtg tatattttat agtgagttta agtagtacta aaaatctaag
     5161 caaaaaatta taaaagagta tattttttta tagtttaaag tggttataac ctcattacca
     5221 aatgtaaacg ttacaagtat gaaaggagaa tgaaaatgtt taaattagaa gaacaaaaac
     5281 taaaagattt aggtgcaata ataacaacta atgaaataaa acaacagcct gaattatggt
     5341 tagagactta tgaaatatat aaatctaaca aagaaaaatt aagtagattc atagatacaa
     5401 taagtaataa tcatgggcag tttagagtta tatttacagg tgctggaact tcagcttaca
     5461 taggaaattc aatacttcct taccttaaaa ataaaaatga cataagaaaa tacatatttg
     5521 aagcaatacc tactacggat atagtttcaa acccatatga ttacttaaaa aaagatatac
     5581 caacattatt aatttcattt gcaagaagtg gaaatagtcc tgaaagtttg gctgctttaa
     5641 atttagggaa taagattgta gataattttt atcatttagc tataacttgt aatccagaag
     5701 gagaactagc taagatgact aaaaacgacg aaaataatta cttgttatta atgccatcaa
     5761 aatcaaatga tgaaggcttt gccatgacag gaagtttttc gtgtatgatg ttatctgcta
     5821 tgttaatatt cgatagttta gaagatgatg tagaaaagtc atatataaat gcaatagttg
     5881 aaatgggaag aaatgttata gatagaaaag atgaaataca tgagttaata aataaagatt
     5941 ttgatagagt tgtatattta ggttcaggag gattaggtgg tttgacacaa gaagcacaac
     6001 taaaactttt agaacttaca gcaggaaaaa tatctacagt gtatgattct cctatggggt
     6061 ttagacacgg accaaaatca tttattgatg aaaatacact tgtatttgaa tttgtatcta
     6121 actgtttata tacaagaaaa tatgatttag atgttttaga ggagataaaa agggataaaa
     6181 ttgctaaatt cacttgtgca gtgtcagtag aaaatgaaaa taacttctca ggaacaaagt
     6241 ttgagtttaa agaaaagtat aataaattac cagatgtgta tcttgcaatg ccatacatat
     6301 tgtttgcaca aactatagca ttgtttgtat cggtaaaggt tggaaataag ccagatacgc
     6361 catcagctac aggaacagta aatcgagtag taaaaggtgt aacaatatat gaatattaaa
     6421 agataagatt aaaatattat aactaaataa tttgggaggg tatcaatgtg gcattagtaa
     6481 caacaacatc aatgcttaaa aaggcacaag atgaagggta tgcagtagga gcatttaatg
     6541 tagaaaatat ggaaatggta attgctgtta tagaagctgc tgaggagtta aattctccag
     6601 taatattaca aactactcca tctactgtaa aatatgcagg tcttgattat tatctagcaa
     6661 atgcaaaggt tgctgcagaa agagtaaaga tacctgtagc aatgcatctg gaccatggtt
     6721 caagttttga ccttgcaatg aaagctttaa gaagtggata tacatcaata atgatagatg
     6781 gttctcatga aagctttgaa aataatatat ctatatctaa atcagtagta aaagcatgta
     6841 gtccttctct tataccagtg gaagcagaac ttgggaaagt tggtggaaaa gaagatgatt
     6901 tagatggcgg gaatagtaat gattatacaa atccaaaaga ggcaaaagag tttgtcgata
     6961 gaacaggaat atcttcattg gctattgcta taggtactgc acatggattg tataagggtg
     7021 aacctaaaat agatttagat aggttatcag aaattaaaaa tgtagtttca atacctttag
     7081 tattgcatgg aggttcagga atacatgatg atattataaa agaagctata aaaagaggta
     7141 ttgcaaaagt taactatgca actgaattaa gaattgcata tagtaaaggg gttaaaaaag
     7201 ttttagatga agattctgag gttatagacc ctaaaaagta tggattagca gggcttcaat
     7261 cagtaaagga ttttgtgaaa gaaaagatta aagtgtgtgg gtctgtaaat agagtataaa
     7321 aataaaatat cctaaattta ttttagataa gtttaggata tttgttatat gaaaaattta
     7381 tattaattat atgtaaatgg tgtatttttt tcatttaatt gatgaaaaat atcagctttt
     7441 attggtaaag tattacatat ataattaaaa tatactaaaa attgaactat atattttatt
     7501 attataaaat atttatatta aattgtggaa ttaaaatata ctaggatata aaattcttaa
     7561 ataaaaagaa aagattgttt ttataaaaaa tattttttat accacttaaa aaaacacaat
     7621 aataacactg agggaggtgg ggatatgaga gaacgcatta ttcttgaaac attaaaaaat
     7681 agtagtggtt atctaaacat agattatttt gcagataagt tgggggtatc tactcgaact
     7741 atcagaaatg aaataaaaaa gatagaaact ataaaagaat gtaatggttt taaattagaa
     7801 tataagtcta aattaggata tattctaaat attaaagacc aagataaatt cgagcattat
     7861 ctaagaaact taccctcaga tttagttgaa aatccagaac aacggttaga gtctataata
     7921 gtagaacttt tagtaaatga aggttataaa actatagaac agttaagtaa aaaatttcta
     7981 gtaagttcat cccaaataaa aaatgattta aaaaagatag atgaaaagat aaaggataca
     8041 gaattaaaac tagagcgaaa ggctcattat ggaattaaaa tagaaggttc tataaaagaa
     8101 attcaaagta tattggtgga tagttatttt agagggaata gaaatataac agagtacagg
     8161 aataagttta tagataattt aaaattagct aatattagaa gtacaataaa aaatgtactt
     8221 aatgaacatg atttagaagc aaatttaaca gaacttgagg aaatattagc acaaattatt
     8281 atattgtata taagagttag tatgagagta gcgggaaatg ctagcgattt aaaattatat
     8341 acagaagatt taattataga taaattatta gataaaattt ttagagataa aaaatataac
     8401 cttaattatg atgaaaagta ttatttaaag gagcttataa aactaaagac taaagataag
     8461 aaagccacta taaagaatat tgataagaat aaacttcaag atattatgtt cgaatttttt
     8521 agagagatag ataaaaaata taactctaat tttttagaag ataaagagtt ctttaactta
     8581 ttttacttac atattgcatg tttaatagaa cgtataaaga agaaccacaa gataataaat
     8641 cctttttcag ttaaaataag tcaacagtat ccaactgttt ttaatttatc tattcaattt
     8701 tcaaaaatca tagaaaatga gtatcatata aaaataagtc aagatgaaat agggtttata
     8761 gctactcaca ttgctgttcc ttttgaaaag agagaagaag ctaattttaa taaaaaatat
     8821 aaaatagcaa taatatgctc ttctggtgga ggtagtgcat ttttgataaa tttaagactt
     8881 aaagaaattt ttccaaatgc tgagataaga aatttttcat tactagaaga aaaagctgta
     8941 atagaatttg caccagattt gattttttca ataacaaatc ttttatttga aataaatgct
     9001 ccagttatac ttataaatga aattttagac gaattggatt atttagatat taaagaaagt
     9061 gttagatttg cagaccatat aggaaatata tcaagcccaa aacaatatat attaggtcta
     9121 tttgataaga atcactttag gtgtataaaa gataaagcta agtataagga tatccttgat
     9181 agtatgtcaa aatgtatagt tgacgagggc gcttgttctc caacctatcc caaagatgta
     9241 tgggaaagag aaagctattt gagtactatt tatacaaatg gggtggctat acctcatcca
     9301 atcgagatga caggaaacaa aaatataata tcagtagctt tgatacaaac tgatattatt
     9361 tatgaaaata gggtgcctaa aattattttc atgatttcat taataaaggg aaatttagaa
     9421 cttcataagc aaatatctaa atatttaagt aagattatgg caaataagga tatggtagac
     9481 atgctaaata agtcacaatc ttatgaagag tttatgtata agttaaaaat ctatctggga
     9541 ggttagacat gaatatagag ttttttaaga ggttgtcaga agcagatggt atagcatcta
     9601 atgaagaaga ggttagacat gttttattgg aagaactaaa agcttatagt gataaaatta
     9661 tctgtgatgg gctagggagt atcatctttt ctaaaataaa agatgagagt gcaccaaacg
     9721 taatgatttg tgctcatatg gatgaagttg gatttatggt gagaagtata gacaaacttg
     9781 gtatgattca cttaataaca ataggaggag taaaacctct tgcacagttt gtacaaaaag
     9841 ttagaattac aacaaaagaa gggaagaaaa tccctgctgt cataaatgct acatataata
     9901 atggtaaggc tgaaaatata tatgcagata ttggagcata tacagaagaa gatgtatata
     9961 acctagggat taatgttggg gatatggtaa catatacaac aagctttgag gaatttactt
    10021 taccagaccg attagtggga aaggcttttg atgataggat aggatgtttt gtgatgggag
    10081 aagttttaaa agaacttagg aaagaaaatc taaattgtaa tattcacttt gcggctacaa
    10141 gtagtgaaga ggttggaata aggggagcaa agacatcaac acagttaata aatccagata
    10201 tagtatttgt aatagatgta gcatgtgcta aaaatgagtt tgtgagagac tatacaaatc
    10261 agaaacaaat tgataaaggt gtaatgctaa tgcatagaga taggactcta gtccctagta
    10321 gaaaaatgat agattatgta atggaaattg ctgataaaaa taatatacca cttcaacatg
    10381 atatgtttga atcaggtggg actgatggag gagaagcaca tctcgtaaat gaagggaaac
    10441 cttgtgtagt aacttgtgta ccagttagat atggtcattg tgcattttca atagtaagta
    10501 ataaagattt agagaacatt ataagattgt atacacagtt aattttaaat tttgatgaag
    10561 aacaatataa acatataaga aattttatct aaaggagaat aagaaaatgt caacagaagt
    10621 acaaataatg gaacttatat caactgcagg agagagtaaa tcgaaagctt ttgaggcttt
    10681 aaaaaaagtg aagtcaaaag attttaaagg agcaaaattg ttaatagagg aggctcgtaa
    10741 aatagatatt gaagctcaca ggatacaaac agaattaata actcaagatt taaatgaaga
    10801 tgttgaaagt ccagcaatga gtcttttaat ggtacatgct caagaccact atatgacttc
    10861 tcagctagca aaagacttga tagaggcttt gatatattgt cttgataagt aattgtaata
    10921 tagaaataga ttatttatgt aaaaattctt ttaaaagttt agatgctttt aagagataat
    10981 aaaaatacaa actttaggag gaattattat gaaaatatta ttatgttgtg caggtggatt
    11041 ttctactaat atgttaatgc aaaatatgaa aaaggtggta aaagagagtg ctaaactcaa
    11101 tgaaaaagat tttgagttta cagctatacc agcagattca atagaaagtg aagttgatga
    11161 ttgggatata gtacttatag gtcctcaaat agctcacaaa atagacttct taaaaggaat
    11221 attagagcca aaaaataagc cttttgcagt aatagataaa gatgtatatg gaaaaatgga
    11281 tggagctaca gttatgaagt tggcattaat aacttataag aaacatcaat tagctcaagg
    11341 ataataaaaa taatgaggga aaagggagat tagatatgtt ttcaaaattt gaagcattta
    11401 tgaatagagt atttatgcct ttagctcata aggttgacaa tcaacgtcac cttggttcta
    11461 taaaggctgg tatggttgct atgacaccat tcacaatatt aggaagtata tttgcaatac
    11521 ttccagcact tccaaatatg cttggagaaa ataatccaat aagcaaattc atacttaaca
    11581 attcagcaat attggattta ccagtaagtc tttccatagg tttaatagga ttatatgctt
    11641 gtatgtgtat tgcttttaat ctggggaact actataaatt atatatacca ggttgtgttg
    11701 cactatcaac tttttctttt ttattcctag tagcatcatt tacaccagat ggagctttag
    11761 aaataggaaa tttaggagct aaagggctat ttacaggtat gatagcaggg cttggttctg
    11821 tggagttata taatttttgt aataagaaga atatcacaat aaaaatgcca gaaaatgtac
    11881 ctgattttgt atctaggtct tttgaattaa tacctactac tataatagtt tgtggaactt
    11941 ttatagttgc tcgttttatt tcattaaaag tatttggaga attacctcca cagatactta
    12001 ctcaattttt atctccatta gtaggaagta tggataaccc atggtcagtt cttgcactta
    12061 actttgctat atgtactata ttcttttttg gaatacattc atcagtattt agtcctataa
    12121 ctagacctat aatgattaca tttatagctg aaaacatagc agctatgcaa gctggagaaa
    12181 caatacctca tttctttaca gcaggagctt caagtgcatt ctttggattt acaggatgtg
    12241 gaattagtat aggttgtgta attgcatgta tgttatcaaa aaatgcttcc tataagaaga
    12301 ttggacgtgt atcattattc cctgcattat ttgggataaa tgaaccaata ttatttggag
    12361 caccgataat attaaatcca ataatgttta taccacatgt atttggtgga gctataatag
    12421 gtacactacc aatgtttttt atgcactggg gatggttagc aaagccagta tttgaccctc
    12481 catatgtagg ggtattctta gaaggatttt taactaatgg agattggcat tctatattag
    12541 caaatgcatt gcaattagta ttagcagttt tattatattg gccattcttt aaaataatgg
    12601 aacgtcaaca aaataataaa aaacaaaaag aagaaactaa gaatatattc tctaaagaag
    12661 aagaagactt attggatgat ttaggattgg atttctaata ttttgttatg aataatacaa
    12721 tggagagatt agtatcctta atctataaaa gaggtgttga cgctcttttg attaaagcaa
    12781 aaaatactaa aagatatata ggagctttat caggtagtgg tgtatatgtg cttgttacta
    12841 aggataaaaa ttatcaaatt ctagatggca gatatattga tgaagcagat aaaaaaacga
    12901 ctggtttcat aaaaaggatt gtatctcaag gttcttatat accaactata attgagttat
    12961 taaaagaatt aaatataaaa aagttagcaa tagaaaacca agctatgagt atacaagagt
    13021 atctttcact aaaaaatgaa ggttttgaaa tcaatttaat aacaaatgaa ttatggaagc
    13081 taagggctat aaaatctaaa gaagaaattg aacttattaa aaaggcttgt gaaattacag
    13141 atgaagtatt tgatgaggtt atttctgaaa ttaaaaaaga tatgactgag ctagaagtat
    13201 cagctctaat tcagtatcat gcattaaaaa aaggtgcaag tggaatgtct tttgaaacaa
    13261 tagtggtatc aggagaaaga ggtgcaatgc cacatggaag acctacaaac aaaaaattga
    13321 aagtgaatga agctataaca atagattttg gtgttgttta tcaagggtat caatcagaca
    13381 tgactcgtac aatatctata ggtaaacctc ctaaaattat taaagagata tatgatgtag
    13441 tattggaagc acaattatct gcaatagagt caataaagga aggaactagg gcaagtgatg
    13501 ttgacaaagt ggctagaaaa attatagata aacatggatt tggcgaatat tttaatcatg
    13561 gactgggtca tggtataggt cttggagatg gtgaagtccc cactttaaat ccaaatagtg
    13621 aagatatatt agtggaagga atggtaatgt cttgtgagcc aggtatttat attccaaatg
    13681 tagggggagt tagaatagaa gatgacattg ttataataga tggaaaaggt gttccactca
    13741 ataagacatc caaagagttt ataatattag gagagtaaaa ttatgaaata taattttaat
    13801 aaagtattaa atcgtaaaga aggaaattgt agaaaatgga gcaaccatgt gattaaagaa
    13861 aaattcggct taaatgaaga tgcaattcct atggatttag ctgatatcga ttttgagtgt
    13921 gctcctgcta taaaagaatc tatcttaaaa agagcatcag taggagatta tagttatact
    13981 tttataggag atgacttcta tgatgcgatt ataaattgga ataaaagaag atttgatgta
    14041 tatatagaaa aggattggat aaaattaact tttggtactg tttcaaccct tcattatata
    14101 gtccaagcat atactaaaga aggagagggt gtattgataa atacacctgc ttatgaccct
    14161 tttgcagagg ctgtagtaaa taataataga aagttgtgtt gtagctcatt aaaattagat
    14221 aacaatagat attatttaga tttagaggat atggaaaatc aaatgaaata cgagaatata
    14281 agattgctta tattctgtag tccacaaaat ccatcaggtc gtatatggac aaaagaagaa
    14341 ctatatcaag tgtcagagtt atgtttaaag tataatgtaa ttttggtaag tgatgaaatt
    14401 catagagata taatatttaa agattataga tttgtatctt tatggaatgc tcatccagaa
    14461 atttataaaa atagtataat ctgtgtatct cctaataaag gcttcaactt aggtggatta
    14521 aaaacatcat atgtattaat aagagatgta aaaattaggg agactttatt agaaagacta
    14581 aaaagtaatt caataacttc tccaaatgta tttgcaatac cagcaatagt tgcagcatat
    14641 aatgaaagcg aagaatggct agatgctatg actagttatg tagaggagaa ttttgaaata
    14701 gtttatgatt tctttgaaac taatatacca aaagctaaag tgatgaagtc agactcttct
    14761 tttttagcct ggatagatgt aagagaagta tttagaaatg aagaagaatc taaagaattt
    14821 tttagacatg caaacttaac tatggtagtt ggaagttatt ttgtgaaaga tggagatgga
    14881 tttattcgta ttaatgtggg gtgtcctaga gaaacattaa atgaggctct aaatagaatc
    14941 aaaaaaacgt atataagtat gtattgttaa atcataaaaa aagtatctat ggtttatata
    15001 aaaacacatt atttagttat caaatattac tggaattttg tattccagta atattttttg
    15061 attaaggaat attattgagg aatattaaat aatattattt cataccctta tattaactta
    15121 tataaaaata ttttattatt ttgggaacgg gttagctaac ctttatctag tgtatattta
    15181 tattgtaaga agcagtaaaa acttttcctt tactaagttt attaataaac ttcttatctt
    15241 tataaatttt gttagaattt atactatcag caagaccata ccaaggttct atacataaaa
    15301 aaggagcagt agaattagtt tcactataat aaggagtcca aataccaact agagggaaat
    15361 cttccataga tatagttaca tatttactac catcattatt acatatagat acttcatcta
    15421 tgttggtgta tatcaaagca tcattcttga atacttctgg atttaactgt aagtttttta
    15481 attttccaat aggtattata tcatctgtaa aagaaccatt taaattgatt ttttctacat
    15541 catttttact tttaaactca aggtagtgtt tagaaaaatc attttgttcg taaaaaggaa
    15601 ggttgaatgc aggatgtcca cctatagaaa agaatatatc tttagaatca gtatttttta
    15661 caatccattc tacctcaata ctattatcat ttaatgtata gtttatgatt agctcaaaag
    15721 aatatggata cttctttaaa gtagattcat tatctgttaa tttataagtt acaaatgtat
    15781 ctcctttatc tacaatctca aagtccatat ctctagcaaa cccatgttga gtcatgctat
    15841 ataaattttc ttctattatt gtttcattat caaaaagttt acctactata gggaacaata
    15901 taggtgattg tctaccccaa tattttttat taccatccca aagaatgttt ttgtcgtatt
    15961 ttttagaaaa tattttagtt agttcagcac caaaactgct tgattcgata attaaatttt
    16021 cattttgtaa tatattcatt taaaatctcc tttattatat tttatgagta tattatacta
    16081 taaagtataa agattattaa attttatttg atattatatt tgaaaggtag attttagtat
    16141 attttgaaaa ttttgttttg aaaatttggg attatttaag aaattttgta ttataaatag
    16201 aaggaaatag ataaattgta tagaataaaa tatattaaga taagttaata atgttaaatg
    16261 ggaagtgagt ttatggaaaa accaaataca aaagttgtta actttcaaga gtataaagac
    16321 agaaaaaacc aaagagaagt aaatagagac gaacttttaa agcttataaa aaaaattgtg
    16381 acttcaaaat agggagttgt taaactccct attttaatgg gtttcataat aattaagaca
    16441 ttctgagtcc atctatataa tctttgaatt gtgagaaatc tgattcacta cttaattcta
    16501 tggtttctga accttccgta taaaaattct taagatagat agtataatta ttatcaacac
    16561 aatcatgata aatacatcta tatccatctt catacaaact ttttaactta gaaaaatcat
    16621 ccacaatatc atctccttaa agttctttta aatatatttt tacaaaaagc atctaattgt
    16681 atgcaaattg acaatgtaaa ataaaggaaa tgaacataaa atgtagaata atttttatat
    16741 gtatgtaaaa ataaaaagaa aaagttgaaa tttttagaaa ataagagtat tttttatcta
    16801 aaaagagagt ttaaaaaata aaaaaatgtt gggaggataa aaaatgagtt tattagaaag
    16861 tatatcaaaa aacatatatt ccctagataa ctcttctatt gaaaaaacaa agcagagatt
    16921 ggataggctt atacatccaa ctggaagctt aggaaagata gaagatattt gcatgcaatt
    16981 agcaggaata tttggcaatg aaaattttga cacaagtaaa aaggttataa ttgcttttgc
    17041 gggagaccat ggtgtatatg aagaaggcgt agcacctgac cctcaaaata taacaaaatt
    17101 acagtttcca aatttttcga aaggtctatg tggagttgga gtaataagta aatttgtagg
    17161 ggcagatgtt gtagctgtag atgtaggaat aaactgtgat gaaaaactgg atggggtatt
    17221 agactacaag ataagaaaag ggacatcaaa tatggcaaaa ggtccagcta tgagtaaaca
    17281 agaagcaatt agatgtttag agataggtat tgaaatagca gagcagtgta tagaaaaaga
    17341 ttataaggtt attggtattg gggagatggg tatagcaaat actactccaa gtacagcaat
    17401 aatatctgta atttcagggt gtgacccgtt agaagttact ggtataggtg caggtcttaa
    17461 gaaagaaaga ctaaagcata aggctgaagt aattagaaag gctattgaaa ttaataatcc
    17521 aaatccaact gatggagtag atattttatc taaagtagga gggtttgaaa taggctcaat
    17581 ggcaggtgtt atattaggtt gtagtgctaa taggattcca gtagtaattg atgggtttat
    17641 ttcttatgca gcagcattaa ttgcatataa gataaatcca aaaactagag aatatatgat
    17701 agcatctcat ttatcagcag aatcaggaac taaaagagca ttagacatat taaaattaga
    17761 ccctctatta aatatggata tgagattagg tgagggaagt ggagctgctt tagcatttga
    17821 tataatagaa gcttcaaact atacttataa aaatatggca acttttgatg aaattgacat
    17881 gggaagataa atataaaaat ttaatatgta ggagtgtttt gatgagtaaa attattctag
    17941 taacaggagg agctaggtca gggaagagta actttgcaga aaaactatgt tttgacagaa
    18001 ataataatac agcttatata gcaacctcta ttccatttga tgatgaaatg aaagatagag
    18061 taaaaaaaca tcaagagaat agacctagaa actggaatac ttatgaaata tatgaagata
    18121 tatattccat aattaaggag atatataaag aacatgaaac tgttatacta gattgtgtaa
    18181 cattattagt aaataatcta atgtttgaac acaatctaaa tatagaagaa tctagtcaag
    18241 aagaaataaa caaattagaa caatacataa aagaacaagt tgtcaaactt attgaagaaa
    18301 tagaaaaaac aaatctatac tttgtatttg taacgaatga gttaggtatg ggaattgttc
    18361 ctgggaataa acttagtaga atttatgctg atattgtagg tcgtataaat caatatatag
    18421 cttcgaaaag taatgaagtt tattttgtag ttagtggcat agctatgaag ataaaggagt
    18481 agtatgcaat tatgaaaaga tttattttaa tactacagtt tttgacaagg atacctataa
    18541 aattaaatgt aggatttgat gatgaatttt ataagtcaat agtatatttt ccacttgtag
    18601 gttttgtcat aggtatatta tcctatttaa taggatggat ttctatgctt ttatttgaac
    18661 catttatagc ttctataata ataactctag ctggtgtctt aattactgga ggacttcata
    18721 tagatggatt aggagataca tttgatgcaa tatatagtta tagggataaa gaaaagatgc
    18781 ttgaaataat gaaagattca agattaggta caaattcact tctagcaatt atgtttgtac
    18841 ttttattaaa ggttggattc gtttacgata taataagtaa taattcattg tgggttataa
    18901 tttttatgcc aatgattgca aggttaggag taatgttatt gacatataaa actgtgacac
    18961 caagagaaaa aggaatggga aatttattta taggaaaatt aactacaagt atgttaataa
    19021 ctgctataat atacacatta ttgatagttg ctcttattac taaatttata tttttattac
    19081 ctaatatagt gttgattaaa gtattaggtt cgattatagt ggtttttgta tttataatat
    19141 tattcaaaaa acatatttat aaaaaaattg acggagtaac aggagatata ttaggctgtg
    19201 gaatagaact ttcagagctt gtatatttaa tttacatata tttgttaatt tttatgtttt
    19261 tttaaagtaa aaagtggtga taatatgata agattaatat taataagaca tgcactgaca
    19321 aatgataata aaaaaggaag attatcaggc catataaata gttgtattag tgaagagggc
    19381 aaactacaaa taaataaaat taccagatat ctgagtaatg aaaacataga taaggtttat
    19441 acaacaccat ctacacgtac taaagataca gtagaaaaaa tatcaaaatt gaaattatta
    19501 gaaatagaag aaaaagaagc tttaagagaa attagttttg gagactttga aggaagaact
    19561 tttgaagaaa ttaaaatcaa atatccaaat gagtttgaaa aaatgataaa agaaggtaac
    19621 aactatagat atccaaatgg agaaagtttg atagactctt ataaaagagt ggcaaaagaa
    19681 attgataata taattttaga aaatgatagt aatttagata caaagacaat acttatatgt
    19741 tctcatgcag gaacaataag aaatataata acacatttga tttctggtag ttataagtat
    19801 cactggaact ttaaaattga taatgcatct attacagttt tagaaattga tggtggattt
    19861 gctgtaatag ataaaatgaa ttttacagac ttcatataat ttaatcaaaa ccaaacatta
    19921 caatctgtgt ttgtaatata tctgtaaaat tagcaatgaa aatagaatat tagattaaaa
    19981 ttaggttctt aattagatgt taaaagggaa aaaggttaga tgcctttgca gcccccgcta
    20041 ctgtgaaacc aacgaaacta taaataccac tgtcagtttg atgggaaggt tatagaagta
    20101 ggatgaagtt aagccaggat acctgcctaa tttaatttaa aacaagaggt cttcggggtg
    20161 aaagattttt aattaatata tataaaagtc ctatctttag aagtattagg acttttttta
    20221 atttgttttt tagtaaattt taacaaggag ggatggaaag tggggaaaaa aataatgcta
    20281 caaggaacag cttcaaatgt aggtaaaagt gtcttagtag caggtttgtg tagaatattt
    20341 aagcaagatg gttatactgt tgctcctttt aagtcacaaa atatggcttt aaattctttt
    20401 ataactaaag aaggattaga aatgggaaga gcacaagtat ttcaagcaga ggctgcgaaa
    20461 atagagccaa tagctgatat gaatccagtt ttattaaaac cttctggaaa taataaaagt
    20521 caagttattg taagaggtaa agttgtagga gaaatgcctt cttctaagta tcatgattat
    20581 aaattggagt tagtagatgt gttgaaggaa acatttaata gcttaaattc aaggtatgat
    20641 attgtagtta tggaaggggc aggaagtaat gcagagataa acttaaaaga tagagatatc
    20701 tctaatatgg gtatggcaga aatagctgat gcacctgtaa taatagtcgg agatattgat
    20761 agaggaggcg tatttgcctc attagcagga acaatgcttt tattaaatga agatgagaaa
    20821 agaagagtaa aaggtgtaat aatcaataaa ttcagaggaa aaaaagagct tttacaagat
    20881 ggtgtaaaga tgctagaaga catcataaaa gtacctgtta taggagtagt accttataca
    20941 gatataaaga tagaagatga agacagtgta actacgagat ttaagaaaaa aatgaataaa
    21001 agtgatatac acatagaaat aattagaact ccacatatgt caaattttac agattttaat
    21061 atatttgaga cacaagaaga tgtaagtatt agatatgtag actatggaga atctttagga
    21121 aatccagata tattaataat acctggaact aaaagtacta tagacgattt aacatatata
    21181 agaaaaagtg gtcttgaatc gcaaatcaaa aatttacata gtcaaggtaa attgatattt
    21241 gggatatgtg gtggatacca aatgttaggt aaaaaattaa aagaccctta tcatgttgaa
    21301 agtgaaattg aagaagttga tggaataggt cttttagata cagaaacaac gtttgagaaa
    21361 gaaaagacta caacacaagt agaagctact attgttgaat gtattagtga atacatgaat
    21421 aaccttaagg gaaaaaaagt aaaaggttat gaaattcata tgggaattac aaagcgaggt
    21481 aatgatgtaa gaagtttaga tttaataact aaaaaacttg ataaagaagt gaattatact
    21541 gagggaagtg taaataaaga ggggaatgta attgggactt atcttcatgg aatatttgat
    21601 gaaataagct ttacaagagc aattttaaac aatataagaa agaaaaaagg tttaggagaa
    21661 ttagaaagca aagtaaactc ttttaatgaa tttaaggata aagagtatga taagttggct
    21721 gattttttaa gagaacattt agatatagag aaaatatatg agattatgaa ataatgatga
    21781 cctttattta taatttaggt aggaggtgta ttatgaaaaa aattttaatt gcgggtacta
    21841 atagtggagt aggtaaaaca acaatatcat taggaataat gcaagctttg gttaagagaa
    21901 atatgaaagt acagccatat aaagtagggc cagactatat agacccttca tatcacactt
    21961 ttataactgg aagacattct agaaatttag attcttatat gttagatgat gaaaaaataa
    22021 agtatatagt aaataagtcc tcaaaagatg cagatatttc agtaatagaa ggtgttatgg
    22081 gcttatatga tggctttgga atagatttag ataattgtac aagttcacat acttcaaagg
    22141 tattaaagtc acctgttata ttagttataa atggtaaatc tatggcagca tctagtgctg
    22201 ctatggtact tggatataag gaactagata aagatgtaaa tataaagggt gttatagtaa
    22261 ataatgtaaa gactaatagc cattatcaaa taattaagag ttctatagaa aaatattgta
    22321 atgttgaagt attggggtat tttcctccaa ataacaaatt ctctttggaa tctcgacatc
    22381 taggattagt tcctagtgta gaaatgaaat cactaaggga aaaattttat accttagcag
    22441 atgaaattga acactatata gatattgaca gaataattga aatatcagaa agcgatgaat
    22501 ttgagagtga ttttgatttt caaactttaa tagaaaataa taaaataaaa gaacatgtta
    22561 ataataaatc aatagctata gcatatgata aagcattcaa tttttattat agagaaaata
    22621 tagagctttt agaggaactt ggtttagaaa taaactattt tagccctctt gaagatgtat
    22681 cagtgccaaa tgcagattat atttatattg gaggaggttt tccagaaata tttggaaaag
    22741 aattagaagc aaatgagtca atgagaactt ccatattaga agcacataac aataatatac
    22801 ctatttatgc agaatgtgga ggactgatgt acctaggtga gaaactattg aatcaagaag
    22861 aacaagaatt taatatggtt ggaatattta gtggaattag taagatgaca tcttctttaa
    22921 aaagatttgg gtactgtatt ggtgtagcca aggaaaatac tcttttatct aaaaaagggg
    22981 aatctattaa agggcatgag tttcatcatt caatatttga aagtgatgaa aaatgtgtat
    23041 attcaatgag aaaagaaaga gatggaaata tagtagaaga gtgggatggt ggttatagta
    23101 aaggaaacac tttggctaca tatcttcata ctcattttta taataactta aattgtatag
    23161 aaaatttttt gaaaaaagga aatgaataaa tgagtatttt atctatttat ataggatatg
    23221 tgacagactt aattgtagga gacccatatt cttttcctca tccagtgaga tttattggta
    23281 aacttataaa ttttactcaa ggtataataa gaaaggtctc taaaaatgat aggcagttaa
    23341 aattgggggg atttatatta tggtttataa ccgttggaat aacatattta acaacttatg
    23401 ctatagtgaa gttatttagt tttaatatat tattgagtat tgtagtgaat agttttataa
    23461 tttatacaac actagccaca aaatgtttaa aagacgaagc attaaaaatt tataatgtat
    23521 taaaaactga agatatagaa aaatctagga ttcagctatc ttatatagta ggtagggata
    23581 ctactaattt aagtgaacct gaaataataa gagcaactgt agaaactgtt gcagaaaata
    23641 ctgtagatgg tataattgcg cctatgtttt atgcatttat tggaggagca ccacttgcta
    23701 tggcctataa agctatcaat acattggact caacagttgg atataaaaat aaaaagtata
    23761 aagatattgg ttttgcatct gctaagattg atgatatagc caattatata ccagctagaa
    23821 tatctgtcat tcttatgaca attggaagtt tctttttaaa ttataactat aggaactgtt
    23881 ttaaaatctc tattagagat agaaagaatc ataaaagtcc aaattgtgct ttttcagaag
    23941 gtgcagtatc tggtgctcta ggaatacaac taggaggtac caacgtttat tttggggaaa
    24001 aagtatataa gccaacaata ggggataagc ttagggagat agataaagaa gatataatta
    24061 aaactaataa aattatgtat gcatcttcat ttgtatctat gttggtattt acactaatat
    24121 atgtgttatg taggatgatt ttaattaact taattatata aattattgtt tgttaactta
    24181 agggggacat agatgaagga tttagggcat ggtgccaatg tagatgaaat ggcaagatta
    24241 tatgggaaaa acccaaaaga aataattgat tttagttcaa acataaatcc aaatgtatta
    24301 ccaaatttag agagatacat tttaaaagga ttagaagagt gtaggaatta tccagatata
    24361 aattatacaa acttgagaga aaatatatca aaatatatag atataaatcc agactttata
    24421 atacctggca atggtgcaac agaagtgatt tatttgctta tgaagagtat taaaaaaaaa
    24481 ttggctataa taaatccgac tttttcagag tatagaagaa gtgctgagtt aaataattta
    24541 gatattatag atttagagtt agatttagaa aataacttta aacttaatat agatataata
    24601 aaagaaaata taaaaagatt tgatagttta tttatatgta atcctaataa tccgagtggt
    24661 aatgtccaag atttaaagga acttgttcat ttactagata aacataataa ggtattaata
    24721 attgatgaaa ctttcatgga atttgttgaa gatgaaagta aatatagttt ggttaaatat
    24781 atagaatcaa ataaaaatat atttataatt aaagctgtga ctaagttttt tggtatgcct
    24841 ggtttaaggc taggatatgg tcttacaagc aacactgaaa ttatgaacaa aatttatgaa
    24901 cacaaagagc catggactat caattctttt gcagatatac tatccaattt tatttttgaa
    24961 gataaagagt atattaaaaa tagtaaagaa tattacatag aagaaagaga atatatgtta
    25021 caagagttga gaaacataag aaatataaag gtctatgata cagatgctaa ttttatcttg
    25081 ataaaaatat ataaaaaaac aactaaagaa ttgaaaaaag atttgtttaa gcaaggaaac
    25141 atattagtta gagatgcgtc taattttata ggattagatg atagttttat aagagtggct
    25201 ataaaatctc atgaagataa caaaattctt atagaaaata tgaaaaattt attgggtgat
    25261 taaaatgaaa tcttatggaa tatgcccagc atcttgtgga gaatttgtac aaggtataat
    25321 tgatgatgaa gaatatttat gttcatatgc aatagatatg tattctaaag tgtatattga
    25381 agaaaaatta gtagatataa atttagggag atataagtca aggttagcaa ttgaaaaggt
    25441 atttgaaaaa tttaatttac ctaaaaaata tactaaaaat atttctttaa atataaatag
    25501 taaaatacct gttggaaaag gaatggcaag ttcaactgct gatataggag ctactataaa
    25561 ggcaacatta tcattgatag ataaagattt aagtagcgag gagatttcta aattagcagc
    25621 agaaatagaa ccaacagatt ctatatttat agataaaaat agtatattta atcctctaaa
    25681 tggaactgtt ataaaatacc taggaaatct gaccaatgcg aaagttgtaa tacttgaacc
    25741 aaacaaagta ctagatacta tgaaaattag attgaggcaa gattataata aattaaaagt
    25801 agagaataaa gaagtaataa aaaaatcatt tgctctttta gaagaaggat tgaaaaaaaa
    25861 taatttatct ctagttggag aggcttgtac tttgagtagc ttagcaaatg agaatataga
    25921 aaaaaaagag tatttaaatg aaataataaa aatatcaaaa aaatatggag catatggagt
    25981 aaatattgct cacagtggaa ctgtagtagg tattttaatt gataagttta tgaatgataa
    26041 aaagatgata gatgccttat gtgaatctaa cataaattct gtctataata aaatttatac
    26101 acaaaacata attaatggag gaattaaggg ggaaatagaa tggaatacat aaagaatcct
    26161 atgaaaatag aagaaaaaag ttttgaattg atacaagaaa taatagacga aattagacca
    26221 gattataaat ttaagaataa tatcgaagaa aaaataataa aaagagctat acatactact
    26281 gctgattttg attacttaga tatattaaaa atatcagaag aagcagttga tagtataata
    26341 gatgcattaa aaaataatgc aagtatttat actgatacaa atatggctct tagtggtata
    26401 aataaaagaa agttagaatc attaggatgt aagtataaat gtttagtggc agatgatgaa
    26461 actgtaaaat tagctaaaga aaaaggaatt actcgttcta tggcagcagt agaaattgca
    26521 gctaaagaag aaggaagaaa aatattcgtt ttaggtaatg ctccaacagc tttatataaa
    26581 gttatggaga tgaaatcaga aggtagatta gatttagatg cagttatagg agttcctgta
    26641 ggttttgtag gagcacaaga atcaaaagat gaagttgaaa aaacagatat accatatata
    26701 atttctaaag gtagaaaagg tggcagtaat ttagcagcag caatagtaaa tgctatatta
    26761 tatactatgt aggtacctat atggaagaat atgtatatat agatggaaaa aaatatagaa
    26821 gaggatatac tacaggttca tgtgcaacag gtgcatctaa ggctgctgta tatatgttga
    26881 ttacaaaaaa tagaattaat actataaata tagatactcc taaggggata ccattactac
    26941 taaaagttga taatataaat atttctgata catttgtgga atgttccata aaaaaagatg
    27001 gtggagatga tatagatgca actcatacca tggatattta tgcaagagct gaaattgtag
    27061 ctaaaaatga taagaacaaa gggtatctta ctctaaagga tatagatagt ttaagcacca
    27121 atagtgagtg taaaagtgag ctctataagt ttattagggt ttatggcgga actggtattg
    27181 gtgtggttac gaaaaaaggg cttagtgtgg atgttggtaa gcctgctata aatccgactc
    27241 cacttaaaat gataaatcat gaaataagaa agcttatagg agataatttt gaatctatac
    27301 ttggaaatga taaagtttta aaaataacaa tctttgctcc acaaggagaa actgtagcaa
    27361 aaaaaacatt taatccaaga ttaggtatag ttggaggaat atctataata ggtacaactg
    27421 ggattgttga acccatgagt gatgatggtt ggaagaagtc tctatctata gaacttcaga
    27481 tgaaaaaaga acaaggctta gataaaataa tattggttcc aggaaatcat ggagaacagt
    27541 ttataagaga aaaattaaac ttagatatta agtatgtagt tagggtaagt aattttatag
    27601 gctatatgat taaagaagct caaagaatag gatataaaaa aatcttaatg gcaggccata
    27661 taggtaaatt tataaaagta tctgctggta tttttaatac tcatagtaag gtagcagatg
    27721 ctagaagtga gatattagtg gcaaacttag ctttaatggg agctagatac gaatttttaa
    27781 ataaaataaa tcaatgcgta actactgaag aagctgtaga gctaataaat aatagtgaat
    27841 atagagaagt atataatata ttaagtaata aatgtaggga gagagtaaag caatacttga
    27901 atgaagattc agatgatatt gatgtggaag taatcatatt ttcaatggat aagtctttat
    27961 taggtaaatc ggataataca gatgatttag tggaggtctt tatatgataa acataatagg
    28021 tctaggacct ggtaacttag actatataac aaaaaaaggt gaaaatttaa tttccacttc
    28081 tgatgtatta attggtggta aaagaaattt agagtctata aaaaattttg aaggagaaaa
    28141 aatagttctg gattctaatt taagagaaat tatagagtac ataaataaca ataaagaaaa
    28201 gcaaatatca ataatagcat ctggggaccc attaatatat gggataggta gatatctatc
    28261 taaaaatatt gataataaga tgttaaacat ggtttctggg attagttcat tacagtacat
    28321 attttcaaaa atatatgtag atatgaatga tgtatatatt acaagtagtc atggcaaagt
    28381 accagatttt gattacatat tatcacataa aaaagtatgt atggttacag attcaaagat
    28441 aggaccaaaa caaataagta gagaaataat agatagaaat ctaaataaaa ttattgttgt
    28501 aggagaaaat ctgtcatatg acaatgaaaa aataacaata gcaaaaccag aagagataat
    28561 aagaatggac aattttgata tgaatgttgt ggtgatttta gatgaggaat agtgaattta
    28621 taacaggtaa agttccaatt actaaggaag aggttagagc aatatcaata agtaagttaa
    28681 atttagtaaa tgctaaaaac ctcatagaca taggggctgg tacaggaagt gtaagtgttg
    28741 aagctgcata taattatcct aatttaaagg ttatatctat agagaaaaat gatgatgcta
    28801 tagagcttat agagaaaaat aaaaaaaaat tcaacttaaa aaatatagaa gtgataaaag
    28861 gatatgctcc aattaatcta gggttaaatg ttaaagttga gtctattttt cttgggggaa
    28921 caggaaataa tctggaagaa ataatagaat ggtctaaaaa aaatctcgtt acaggaggaa
    28981 gacttgtagc taattttata ataatagata catttaatca aactttaaaa ctgcttaaaa
    29041 agcatggatt taaagaaata gatgtatgtg ttttgaatgt ttctaaacta gagaaactag
    29101 gaaaaggtga atattttaaa ccactaaatc ctatatatat aatatcttgt gaaaaagggg
    29161 aaaatgatga tgaataaagt acattttgta ggagcaggac ctggagataa agagctgata
    29221 acattaaaag gatacaaatt attaagtaat gcagatgtag tgatatatgc aggttcactt
    29281 gttaatcctg aacttttgga atactgtaaa gaagattgcc aaatacataa tagtgcacat
    29341 atggatttac aagagataat agatgttatg agagaaggta tagaaaataa taaatctgtt
    29401 gtaagactgc aaacaggtga tttttctata tatggttcaa ttagagaaca agtggaagat
    29461 ttaaataaat tgaatataga ttatgactgt actccaggag taagttcttt tttaggggca
    29521 gcatcatctt taggggttga atatacagtt ccagaaattt ctcaaagtgt aattataaca
    29581 agaatggaag gcagaactcc ggttccagag aaagaatcaa tacaatcata tgctaagcat
    29641 cagacatcta tggtaatatt tttatctgtt caagaaattg agaaagttgt gtctaaatta
    29701 ctggaaggtg gatatccaaa agatactcct atagcagtta tatacaaagc aacttgggca
    29761 gatgaaaaaa tagttaaagg aactttaagt gatatagctg taaaagttaa agaaaacaac
    29821 ataaataaga ctgctttaat aatggttggg agatttttag gagaagagta taataattca
    29881 aagttatatg ataaggattt caaacatgaa tatagagggt aatattgcta taatctgtat
    29941 tacagaaaat ggaaaaaaat tagctctaaa gataaattct ctagtaaata actgtgttat
    30001 atatcatgta aaaaataaaa aaagtaattt agttgttgaa gaaacatgtg tgcatacagt
    30061 tcaaaagaag ttaagtgatt ttgtaggaga aatatttagc aaatttgatt acatagtatt
    30121 tataatggct acaggtatag ttgtacgaag tatagcacca tacataataa gtaagtttag
    30181 tgaccctgca attttggtaa tggatgaaaa aggcaaaaac gtaataagtt tattgagtgg
    30241 tcatattgga ggggcaaaca gcttgacaca gtacataagt agtcttattg atgctaatcc
    30301 agtaataaca acagctactg atataaatca aaaagcttcc ttagatatga tagcaaaaaa
    30361 actaaatgca catattgata attttagaga aagtgtaaaa gaagtaaatt ctatgctagt
    30421 gaataataaa tgtgttggat tatatattga tgaaggatat caagttgata ctaggggatt
    30481 taaacttata gaaagtaagg atgagttaag agatagtttt tcaaacacat atatagaaaa
    30541 attagttgta gtaagcaata aaataaattg tattgaagat attgagaatt taaacctaga
    30601 taataaattt gaacattgct atagtaccaa aaaaataata aaggtaattc caagagatat
    30661 agtgatagga attggttgta gaagaaacac agatagtgaa ctgatgtata attcacttga
    30721 agagtttctt aataaacaaa atatagatat tagagcaata aacacagttg gaagtataga
    30781 actgaaaaaa gacgaaaaag caataattga attatcaaaa atattgaagg tgccatttaa
    30841 aacattttca gtagatgaaa tatctaaggt tgataatctt tttgataaat ctgattttgt
    30901 taaaaaaaat gtgggcgtgt attcagtagc agaacctgta gcatatcttt tgagcaaagg
    30961 taatttgtta gttgaaaaac ataaatataa aggaataact ttttcagtgg ggagaataaa
    31021 aatatgatat acgttgtagg aattggacca ggaagtaaag atacaatgac tttagaagca
    31081 ataaaagcaa tagaagattc tgaggctatt gttggatata agacttatat aaaactaata
    31141 gaagaattta tacaagataa agaaataatc caaaatggta tgaggcaaga agttgataga
    31201 tgtaaacaag cagtagagga agcaaaaaaa ggaaaaaaag tagcagttgt aagcagtggt
    31261 gatgctggaa tatatgggat ggcaggtctt attttagaat taatatctaa agaagatgaa
    31321 gatataaaag taaaggtaat tccaggtgtt actgcaagta ttggtgcagc agctatactt
    31381 ggagctccta ttatgcatga tttctgtcat ataagtttga gtgatttaat gactccgtgg
    31441 gaagtaattg aaaaaagatt gagattggcc gctgaagccg attttgtaat ttgtttgtat
    31501 aatccaagaa gtaagggaag aagtgaacat ctaagcaaag catttaaaat aatgggtgag
    31561 tttaaaggtg gagatacacc tgttggagtg gtaaaagatg taggtagaga aaaagaagaa
    31621 aagtttgtat gtacttttga aaatatggac tttgaaaaag tcgatatgac tacaatggtt
    31681 ataataggaa ataagtctac ctatattaat ggtgaattga tgataactcc aagaggttat
    31741 acagtatgat tttaatttta ggaggaactt cagatagttt atctatatgt gataagataa
    31801 atgaactgaa aaatcaacca tatatccttt cagttactac agattatgga agggaacttg
    31861 cacaacaaca tgcagagaat gtaattttag gtaagcttgg aaaagaagat atgctaaaat
    31921 ttataaaaga taataatata gtaaaaataa tagatgccac tcatccttat gcagttgaag
    31981 tatccaaaac tgctattact tgtgcaaaac tattgaatat agattatata aggtttgaga
    32041 gaaaatcttt aattgaagaa atagattatg ataataaatt tatagtagat acaattgaag
    32101 aagcctgtga aatagcaaat aaaataggga caaatatatt cataggaaca ggaagtaaaa
    32161 atttgaacag atttatagag gaaataagtg ataaaaattt agttgttaga gttcttccaa
    32221 cgagtgaagt catattaagt tgtgaaaaat taggtttaag tgcagataat atagtagcta
    32281 tgaaaggtcc atttagccag tatataaatg aagaaacata taaacattac aatatagatt
    32341 tagtcataac aaaagaaagt ggaatagctg gtgggttctt agagaaggta aatgcatgta
    32401 aaactttcaa tataccagta ataattataa aaagagaatc gattaactac gaaaatgtat
    32461 ttaatgacat aaataaaatt aaagacatac ttgtgtaatt tttaggagga gaatatatga
    32521 agaaagcctt attagtagtg agttttggta caagctatca tgaaacgaga gaaaagacaa
    32581 tagatatatg tgaagataaa ataaaaaatt cgttaaaaag ccatgatttt tttagagctt
    32641 atacatcaaa tatgataata aataaaataa aaaaaaggga tggaatagaa atagataatc
    32701 caatacaggc tttagataaa atatatgaac aaggatatga tgaagtaata atccaaacac
    32761 ttcatattat atgtggcgaa gaatttaaca aattaaaaga acaagtagat ggatattctt
    32821 ctaaattcaa aaagattgta ttaggaagac ctttgcttac acatattgaa gattatcagg
    32881 aagctgtaga ggcaattaag catcaaattc ctcatatgga aagtaatgaa gcagtagtat
    32941 ttatgggaca tggaacactt catgaatcac attcagcgta tccagcattg gaatacatgc
    33001 ttagggataa tggaataaat gcttatgttg gtacagttga agggtatcca gaaatagaac
    33061 atgtaataag aagattaaaa gaaggaaata taaaaactgt aaatttgatg ccatttatgt
    33121 tagttgcagg agaccatgct ataaatgata tggcaggaga tgaagaagat tcttggaaaa
    33181 caatattaga agaaaatgga tttaacgtaa gagttcattt aaaaggacta ggagaaaatt
    33241 cttatataca agataaattt gttcgtcatg ctgtaaaatg tgcagagaat gcgaagttct
    33301 atggtatagg agcagggcca ggagatggtt ctttacttac gataaaagcg gttaatactt
    33361 taaagaaact ggatattcta tacactccag aatcaaaaaa gggtggagat agtctagctt
    33421 tatcaatagt tagtgaatat ttacctgaat cagtggaaat aaagtctagg catttcccaa
    33481 tgagttttga tgggaatgaa aaaagtttag cttgggacaa tgtggcacaa gaaattatat
    33541 cagatgttaa tgatggtaaa aatgtaggat ttgttacatt aggagaccct atgatttata
    33601 gtacatatgt atatataatg aaaagaatat taggagaggt agaagtcgaa actataccag
    33661 gaatttcatc attttccaat atagcatcta atcagaattt tccattagtc atggataaag
    33721 aagctttagt ggtaattcct tgtactatgg aagatgataa gatagagtat gctttgcaaa
    33781 attataattc aatagtattg atgaaagtat ataaaaattt taaagaaata ataaaaaaat
    33841 tagaaaagta tgatttaata gaacatgcta ttttagtaag taattcttcc caagaaagcg
    33901 aaaatgtgtt tacagattta aaagaagcgc accttgaaga taagatatct tatttttcta
    33961 ctatactagt aaataaagat aataaaataa aataggtgaa agcaatattt aaaggagact
    34021 taatatgaat atagtggttg gaactagggg tagtaatcta gcgcttatac aaacagaatg
    34081 ggtaataaat gaattaaaaa agaagtatcc agaaattagt tttgagatta aaatcataaa
    34141 gacaaaagga gatttaattc aaaatgtttc actggataaa ataggtgata aaggattgtt
    34201 tgtcaaagaa atagagcaac aattattaga tggaaaaata gacatagcag tacatagtat
    34261 gaaagatatg ccttcttatt tagcagatgg actaaaattt gctcatacgc ctaagagaga
    34321 agacccaaga gatgttctaa tacttagaga aggatataaa aatttagatg atttacctca
    34381 tggagcagta ataggaacag gaagtaaaag aaggaagttt caattattga aacaaagacc
    34441 tgatttaaat atagtacaag ttagaggtaa tgtggaaact aggatacgaa aaataaaaga
    34501 tgaaaacatg catggtattg tgttggcagc atcaggaata attagagcta atttgcaaga
    34561 taaaataagt tcttatttac ctgttgatgt tgttattcca gcacctgccc aaggagcttt
    34621 agctatagaa attagaagca atgatagtgc gatagaggga atagtaaatt cactgaagga
    34681 tgagaataca gaaatccaaa tattggctga aagaggtttt ttagatggtg taaatggaag
    34741 ttgtcatatt ccaatggcag cttattgtga aataatccaa gataaaatac atcttactgg
    34801 cttatatgga gattcagaag gaaaaaaagt agtaatcaag tctatagatg gagatatttc
    34861 ttctcctaga gagttaggtt taaagttagc taaacttgta ttgaaggagt atgagaatta
    34921 tgaagggtaa ggtttactta gtaggggcag gaccaggtga ttataaactc atgactttaa
    34981 aaggtttaga gtgtataaga aaatcggatg taatagtata tgatagatta gcaaatagta
    35041 gttatttaag agaagctaag cctgattgtg aacttatata tgtaggcaag gcatcaagta
    35101 atcatatttt gccacaagaa gatataaata gaattatagc agaaaaagct aaagaaggaa
    35161 aaattgtaac tcgtcttaaa ggaggagacc cttatgtatt tggcagaggg ggagaagaag
    35221 cagagacttt agtagatgaa ggtatagaat ttgaagtagt tccaggtata acttctgcta
    35281 taggaggttt atgttatgcg ggtattccta taacacatag agaccatgct tcgtcatttc
    35341 atgtaataac aggtcatttg aagggtgatg atagtggaga actaaactgg aatgctcttg
    35401 caaataacaa aggtactctt gtgtttttga tgggaatttc aaacctagag aaaataagtg
    35461 aaaacttaat gaaagaagga aaagataagg atacacctgt tgctcttata agttgggcaa
    35521 ctagatataa tcaaagagtt gttacatcta cacttgaaaa tgtttatgaa actgctatta
    35581 aagaagaagt aaaaccgcca actcttatag tagttgggag tgttgtagga cttagagaaa
    35641 agttgaactt ctttgaaagt aagcctttat ttggaaaaag tattgctgta actaggtcta
    35701 gaaatcaaaa tagtgtattg gtagaaaaaa taatggattt aggtggaaat cctatagaaa
    35761 tacctactat taaggtagaa aaaatacaaa ataatattaa cttagaaaat gaaataaaaa
    35821 atataaataa gtataattat ctaatactaa ctagtaaaaa tgccgtagaa atcttctttg
    35881 aaaagatata tgaaatgaat tttgatttaa ggatattatc taatttaaag gtatgtgcta
    35941 taggttctgc tacatcaaat gagttgaaaa aaagaggaat tatagcggat atagtaccaa
    36001 aaaaatttgt agcagagtca ctgtatgaag agttagcgcc tattttaaat gatgacgata
    36061 atatacttat acctagagca gaaaatgcta gagattatct ggttgacaaa cttaaggcta
    36121 tttgtgaagt aacagaagta catatatata gaacagtaat agatgaggag aaaaaaggtg
    36181 agatattaga tattttaaat tctaatgaca tagattatat aacatttact agttcctcaa
    36241 cagtaaataa tcttgttgaa attataggaa aagaaaatat taaaatatta gaaaaaataa
    36301 aaacactatc tataggtcct ataactacag agacaataaa tagtttggga ataaaattgt
    36361 acaaagaatc tgctacatct actatagatt cgttagtaga tttaattata aaaaattaat
    36421 tttggaggct tgaatatgtt aagaagacca agaagactaa gagcaagtaa agcaatcaga
    36481 aatttggtaa gagaaactaa ggtgaatgta gaagacttaa tatatccact gtttgtagta
    36541 gagggggaaa atataaaaga agaaattaaa tctttaccag atgtctatca tttatcaata
    36601 gatatgctag aagacgaaat aaaagaaata agtgagttgg gaattgaaca tataatgtta
    36661 tttggtgttc cagatgaaaa agatgagtgt gcttcacaag cttttaatga taatggaata
    36721 gttcaaaagg caattagaaa ggtaaaagaa ataaattcag atataaatgt aataacagat
    36781 gtctgtatgt gccaatatac aagtcatgga cattgtggga ttttaactga tactggttat
    36841 gttgataatg ataaatcatt ggagtatttg gctaaaatat ctgtaagcca tgctaaagca
    36901 ggagctgata tggttgctcc atctgatatg atggatggaa gaatacaagc aataagagaa
    36961 gctttagatg aaaatggatt agaaaatgtt ggaatcatgg cttatagtgt taagtatgct
    37021 tcaaattatt atggaccttt tagagaggca gctcattcag caccatcttt tggagataga
    37081 aaaacatatc aaatggaccc agcaaatagc aatgaagcta taatagagac tgaacttgat
    37141 atattggaag gtgcagatat acttatggtt aaacctgcat tatcatattt agatattata
    37201 agaagagtta aagataattt tgacttacct ctagcagctt ataatgtaag tggagaatac
    37261 tctatgctta agtttgctgt gaaggaaggt ttattaaatg aagatgtaat tcttgaatca
    37321 attacatcta taaaaagagc aggagcagat ataataataa cttattttgc taaagacatt
    37381 gctaaactgt tgaaaaaata aattctagca gtataaagaa tatcaaaaag tataggaatt
    37441 gtaattaact attatacagt agttttgttt agacatttat tgaagaataa tagaaactaa
    37501 tttgcaattt ctatacttta tttatgtaac taaataaaat ttggaggtag aagatgctat
    37561 atcctattaa tttaaaatta gatgagttag atgtagttat aattggtggt ggagaagttg
    37621 catataggaa atgtaaaaat tttttagagt ttaacaaaaa tgttactata gtttctaaac
    37681 aaattttaaa taaattttat gatttaaaag gaaatataaa aataataaaa gatgattata
    37741 aagaaatata tataaaagat gcttctgtaa taattgctgc cacaaataat agagagttaa
    37801 atatggaaat aggattatat tgtaaagcaa aaaataagct agtgaatgta gttgataata
    37861 tagaaatatc gaactttact gttccatcat atataaaaag aggagattta cttataagtg
    37921 tgtctactgg gggcaagagt ccttcattat catcaaagat aaaaaaagaa attgaagaga
    37981 gatatactga agattatgag gagtatttaa atgtattagg agatataaga aaaaaggtta
    38041 taaaaaaata cgaagataaa agtaaaagaa aagatgtgct taatatgttg gtaacacttg
    38101 acctagaaga acttaagaag tttgatatat aaaaaataaa ataaaaaatg ttaaaaaggt
    38161 gttgacggat tatttttaag atgatatagt attacttgtc cttaagaaaa gggcaaacat
    38221 aa
//
LOCUS       DAJMZY010000029        37839 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.029, whole genome shotgun sequence.
ACCESSION   DAJMZY010000029 DAJMZY010000000
VERSION     DAJMZY010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 37839)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37839)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37839
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.029"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            196..873
                     /locus_tag="OE968_001454"
     CDS             196..873
                     /locus_tag="OE968_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCP7218738.1"
                     /translation="MYNLLVVDDDVDILNINQIYFSNIGFNVYTSETAKDAMDIVESI
                     VLDCIILDISLPDIDGYKMCNDIKEKVNIPIIFLSNYEHEEEKVRGFLAGGDDYITKP
                     YSLKELELRIYARMRQYKNITSVPNVLKFSALVINVNSRKVTFDGESIDLTTMEFEIL
                     LFLAENKEQVFSKIEIYNQVWKMPDIGDQHTVQVHIAQMRKKINSLSREHQYIQTVWG
                     KGYKFVP"
     gene            945..2960
                     /locus_tag="OE968_001455"
     CDS             945..2960
                     /locus_tag="OE968_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HCP7218739.1"
                     /translation="MKKYNILKGTLIVLIVSLLAITGLNLLYKYDNKYTYKSIRASNG
                     ILTIDNDTFTKGKLVFLIDDWEFYNHKIFKPNDFTEQDIKPEYVFIGQYPDFSMRKGT
                     QSPYGNATYRMRIKNEGKDKLLSLELPEIFSASEVWINGEMVSKLGDVGTEKYRPKIK
                     NSVVSFIAKKNTEIIINVSNFSHYYSGLYYPPALGETKDISNMMFYRLLFYSIICFTT
                     FAIAIFSLSVWFLSNKSKIYLYFGCMCVFFAIHVSYPFVHLLGLPLVSFTYAVEDLSY
                     FMVVLCIICINGSISKIEENKVYRFLILPLGITMSIISIVIPIILLPYDMYFVNIYGK
                     LIDIYKYIVFIYILMSSLVSIYKKTCSEHISSYILVSVNTVFGISILFDAVTSNRFEP
                     IFTGWQTEYCGFVIVILFSVMMINRNRIIIKENEKLTRNLEHEVEVRTNELTTLLNER
                     KRFLADVAHDLKAPVSAIQAFIDLIKVGNIHVDEETRTYLYAINQKSNEVQNRVRSLQ
                     EFTSQDKSIGISEKICLNNFIKEIYENNLPDTQACGVNFETYVLEKKIYAKINKEMLT
                     RAFENLIYNALTFTPFDGKIILSMDKEDGFAIIKISDNGKGIPPENIPKVFDRFFTER
                     DNNEPKGQGLGLYIVKSIIREHGGEIFVDSELGKGTVFTIKLSLCFL"
     gene            3010..3690
                     /locus_tag="OE968_001456"
     CDS             3010..3690
                     /locus_tag="OE968_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCP7218740.1"
                     /translation="MQTKILIIDGDKDNCQKLKGFLEEKGISIDLAYNCEEAIGKIFS
                     NKYDLIFLEIILSDGDGWTLCKKIRNVTTCPIVYMTYINEDQSILNALNSGGDDYLIK
                     PLNLEILYAKVKAILRRMNSYVNNNENNTKLEEYNRTSGVIKLEDKIIKLTPTENKLL
                     NFFIENPEKTLTTKEIYEHVWMNEYLEDNYSVVVAVNGLRKKIEKDYKNPQKIITIRG
                     AGYYFNKE"
     gene            4206..4652
                     /locus_tag="OE968_001457"
     CDS             4206..4652
                     /locus_tag="OE968_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218741.1"
                     /translation="MAISDLAFGTECLKTSFQMLFSVISLVNINLLQAQILIAIGGLI
                     SILAMVSLTLFLSAKCKDSLTSMLIAFSICLIPMGIGVSWIGYLLPPGGIGFKISLLY
                     QMTSFNFLHLGGMSFWTPHIILFFSVIEIPIFIFLAIRTYCKHQVP"
     gene            5033..5950
                     /gene="pstC"
                     /locus_tag="OE968_001458"
     CDS             5033..5950
                     /gene="pstC"
                     /locus_tag="OE968_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HCP7218742.1"
                     /translation="MIVKSRLVGLEKNDNNGNKTKYVIEKVAKNIFLLSALVAVASLL
                     LIIGFVFYKGLRPFIFEGYSFIDFLTGADWVPSANKFGISSMIVASIFATLGALVIGV
                     PVGILTSVFIAEVAPKRLAKIMSPAVELLAGIPSVLYGVFGLAVIVPTIQGIFNLPKG
                     QSLLAIVIVLAVMMLPTIISVSETAIRAVPKAYKEGSLALGASKIETIFKVVLPAAKS
                     GVLAAVVLGVGRALGETMAVILVAGNSPVMPTAITDSVRPLTTNIALEMGYAFGTHQE
                     MLFATGVVLFTFILILNLVLNKLSNKAVN"
     gene            5952..6776
                     /gene="pstA"
                     /locus_tag="OE968_001459"
     CDS             5952..6776
                     /gene="pstA"
                     /locus_tag="OE968_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003460575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HCP7218743.1"
                     /translation="MRKFKENLLKSLVYLSALFTIVSLVVIVGFIFIKGIGNMNFNFL
                     FSNYSASGDGGILPMIITTLYTVVVSIVVATPIGILAAIYLQEYAKKGKAVTAIRFAT
                     ESLSGIPSIVYGLFGGIFFVVTLKMGYSIVAGSLTVAIIILPVIIRTTEEALKTVPQA
                     YRESSLALGATKFQTLYKVVLPSAIPGILSGVILSVGRIIGESAAILLTAGTVAKMPG
                     GIFDSARTLTVHSYLLTKESGDIATAASIGIVLIVIVLALNMLARFVAKKLNKANY"
     gene            6795..7559
                     /gene="pstB"
                     /locus_tag="OE968_001460"
     CDS             6795..7559
                     /gene="pstB"
                     /locus_tag="OE968_001460"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HCP7218744.1"
                     /translation="MELIDKIKMSVKDLDLFYGDKQALKKINMDIKENKVTALIGPSG
                     CGKSTFIRTLNRMNDLIEDVTIKGNISVDGEDIYTSDDVINLRTKVGMVFQKPNPFPM
                     SIYDNVAYGPRTHGLRDKKQLDKIVEESLKGAAIWDEVKDRLKSSALGLSGGQQQRIC
                     IARAIAMRPEVILMDEPTSALDPISTLKVEELIEDLKKDYTIVIVTHNMQQAARISDE
                     TAFFLNGEVIEFSDTKTMFTTPVDKRTEDYITGRFG"
     gene            7587..8240
                     /gene="phoU"
                     /locus_tag="OE968_001461"
     CDS             7587..8240
                     /gene="phoU"
                     /locus_tag="OE968_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HCP7218745.1"
                     /translation="MVNNSLDISIDTLKEQTVLMMEKCEEAIEKSVTCMIEKDLEGAR
                     KVVEDDEEINKLREEIRDKSIELIVLKQPMARDLRFIYSLGNISIELERIGDYAANIA
                     REMLKIGGEAYIKELIDIPKMAKECKSMMSQTREALILFDASIAYDVGTKDDIVDGLY
                     EQVQIDCLKIMHENSNTIDQGVKLLLIGRYLERIGDHITNVCEKIIFAIEGKMVEIG"
     gene            8398..9267
                     /locus_tag="OE968_001462"
     CDS             8398..9267
                     /locus_tag="OE968_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HCP7218746.1"
                     /translation="MKLQKMGMRTIKTGISVTLCMILGDYLVENMFYSLVACIISVQD
                     TVKGSLKTGINRVEGTILGGIIGFIFAIIKAGDPFLCGLGVMCSIYLCNLFKIKSVVV
                     ACVTFLAIHLGVGNSDPVYYSLHRVLDTSVGVLFGVLVNYYVARPNYLNSVIDEFKKI
                     EELSMLLIEDKILRKENLNVEKFEEEVEKLEEIYSKLIDELDYSLSETNIEKIENALR
                     ICREIHFHMQSIELLENKLYLKEHTYKYLKKTYNVDKLDWNIDEEKSPVFNYHLMKIM
                     IEIELLRKLNKSY"
     gene            9354..10790
                     /locus_tag="OE968_001463"
     CDS             9354..10790
                     /locus_tag="OE968_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron hydrogenase"
                     /protein_id="HCP7218747.1"
                     /translation="MNTRNDNSKILEIYKMKLFGELVKAVWNDDIEDIENLPNKILNE
                     DLKDNLNNYFSGKFDKDTMVNLIRVTMGLDVTEDTDKNLKESLHEAVNLDEVKRPIIS
                     VISDACKYCDENNKEDESCKIRSKHINCNEEDVCSACGDCVSRCKLGAISDKIEFIPM
                     IKLLKDIKSPVYAIVAPAFVGQFGKDVSPGKLRTALKKIGFEDMIEVALAADMLTAKE
                     AYDYYEHMKKDEEGCFITSCCCPIWVSLIQNSFPQILENVSPSVSPMIACGRAVKILN
                     PDAKVVFIGPCMAKKKEAMLEDIKDAVDFVLTFKELQEIFDALELNPAIMDESNRVEA
                     SLSGRVYARTGGVSKAVKLSVRRIDKNIKFEEKAFEGTKECMDGLKKVLNKEIEATFI
                     EGMGCVGGCVGGPKRILSVEEGTKNVDEYSESTNMETPFDNLNVLQFLTSLGIKRVES
                     LGEKEEEKVKKIFSRDIKSNKKENKYKK"
     gene            10838..11665
                     /locus_tag="OE968_001464"
     CDS             10838..11665
                     /locus_tag="OE968_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HCP7218748.1"
                     /translation="MKIKDNKAVFHVFIRIFLIAVLILTGTLLEEKINNVPVENISSK
                     GENTLELLSQSNTLGEIIYKASQEETKGPGATSEKVAYITIDDGPSKYTNALLDILKE
                     NDVKATFFMLNQNMKNHKEEVRRVLEEENSIGFHSVSHDIHKLYKSPEVTVGEFNTCN
                     NTLQEITGQSSKLIRLPYGSKPYMPEGSYNKLMANDYLIWDWNLDTQDWKSSTSQIVS
                     NILYYGRKRDELVVLIHEKEQSLNALNNIIRILKERGYTILPITENITPKNFWQENL"
     misc_binding    11961..12223
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            12299..14965
                     /locus_tag="OE968_001465"
     CDS             12299..14965
                     /locus_tag="OE968_001465"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HCP7218749.1"
                     /translation="MENTNLSKTYNPKDFEARLYKKWMDEGYFKSKPNPDKKPFTIMM
                     PPPNITGQLHMGHALDHTLQDILIRWKRMDGYEAFWLPGTDHASIATEVKVVERIKKQ
                     EGKTKYEIGREEFLKRAWEWKDEFGGKISNQLKQLGDSCDWDKERFTMDEGCNEAVIE
                     FFVSLYEKGHIYRGNRIINWCPDCKTTLSDAEVEHEEHDGNFYHIKYPLKDSEDFLEI
                     ATTRPETMIGDTGIAVNPEDDRYKHLIGKTAILPLVGRELPIVADSYVDLEFGTGAVK
                     MTPAHDPNDFEVGLRHNLEQLNTMNEDGTMNEVCGKYEGMDRFECRKAIVADLKEQGY
                     LIKIKEHNHNVGTCYRCHTVVEPRLSEQWFVKMEELAKPAIDILKKGELEFVPDKFDK
                     TYLQWLENIRDWCISRQLWWGHQIPAYYCQECGEIVVARKMPDKCPKCGSTHFKQDED
                     ALDTWFSSALWPFSTLGWPNKTEALDYYYPTSVLVTGYDIIFFWVVRMAFAGMFCMNE
                     KPFDHVLVHGLVRDSQGRKMSKSLGNGIDPLEIIEQYGADALRFTLTTGNSPGNDMRF
                     YMERVEFARNFANKLWNASRFVFMNIDEDIIKNMTRESVKEDLTLADKWIISRANNIV
                     KEATNNMDKFDLGIALQKIYDFTWSEYCDWYIEMVKPRLYGEDANAKSAALYTLTYVL
                     EKILKLLHPYMPFITEEIYTHLPTVEGCIIVSEWPKYNEEDNMAEEEDMMNLLMEGIR
                     SIRNVRAEMNVPPSKKAKLIIIPSEEKIEAIELGKDYFITLASASNVEIAKDKSNVPE
                     DAVGVVIDGVEIFIPLNELVDFEKEIERLSKEKKKLEGEIKRVNGKLANQGFLAKAPE
                     SLIEEEKAKKEKFEEMIKSVEERLTNLESKIK"
     gene            15390..16100
                     /gene="rgaR"
                     /locus_tag="OE968_001466"
     CDS             15390..16100
                     /gene="rgaR"
                     /locus_tag="OE968_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RgaR"
                     /protein_id="HCP7218750.1"
                     /translation="MFRVVICDDEKIQRSILKEFTEKLLSERCLNYQILEFSCGEDLI
                     SKYPEKIDIIFLDIQMKDINGIEVAKKIRKFDEKVEIIFTTAFSEYAPQGYEVRAYRY
                     LVKPIEYSNFAMGVNLCIDNLQRKKERYIVLNSKKGFNRILIDSILYVETVKRDLVVH
                     TIGRDYKANMSMKQAEKLLCENGFFRCHTSFIVNLRRIEDLRDNTITINEQFIPISKY
                     RLKDLKVALTSLLCDIMY"
     gene            17146..18177
                     /locus_tag="OE968_001467"
     CDS             17146..18177
                     /locus_tag="OE968_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HCP7218751.1"
                     /translation="MENICDMNNKVKVAVLDTGIDKEHDYLKDNLVGGIAFECMHDYI
                     FISDKFDDEDGHGTACASIIKKEYEDVELFVIKILRKDGITNIKVLEEALRYLLDTNI
                     RLINLSLSVIGVESVKGLFEVCYELFRKGKIIVCSLANDFDLSYPAMFNNVIGVRGFT
                     LDGDDSFWYNKKYDVQCVMDSNSYISCDINNSYRLPPKCNSYLSAKLTGKIAKILSEK
                     PGITISDLNDKLESLATRNHWDSCDFDECSRIVNFKLDLYDKENALFMKVADVVRDCL
                     DIEENNEKLFKGSLFNKEIGLVYDNCFNLLKKLEHRFDIKFNYMDISKYDLVSIYTLT
                     ELVERYKNL"
     gene            18310..19608
                     /locus_tag="OE968_001468"
     CDS             18310..19608
                     /locus_tag="OE968_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HCP7218752.1"
                     /translation="MKYEEALEYISQTNKFGIRLGLENIGKLLELLGNPQETLNIIHV
                     AGTNGKGSVCSFVSNILRECGYKVGLYTSPYLETFTERIRVNGQNIPQDDVARIIELI
                     KEKIEIMVKEGYAYPTEFEVVTAMAFYYYSEQKVDFVALEVGLGGRYDATNIITKSLV
                     SVIVSISLDHTGILGDTIEKIAYEKAGIIKENGVVLVYDQTDEAKDVIKSVCKEKKAK
                     YIEVDFDDINIKKSDINSQIYDCTVMKETYRDLEIKLIGEHQINNSILAISVIKYLKD
                     INKLANINEESIRKGLINTKWPGRIEKIKENPIFIIDGAHNEDGAKSLAKALDKNFKG
                     RKLTLLIGMLEDKDIDSVLEILLPHFNKVITTTPSNPRAINSDILREKVLKYVDDVTS
                     KHEIEDAVNYTLETSSEDDIIISAGSLYMIGTVRTLVKKL"
     gene            complement(19722..19967)
                     /locus_tag="OE968_001469"
     CDS             complement(19722..19967)
                     /locus_tag="OE968_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03905 family TSCPD domain-containing
                     protein"
                     /protein_id="HCP7218753.1"
                     /translation="MKVTFNPSGVCCREMIFEVDENNVIVDAEFIGGCNGNLSGLRSL
                     IIGQNALEVADKLNGIDCGGKGTSCPDQLSKAIRQSI"
     gene            20115..20981
                     /locus_tag="OE968_001470"
     CDS             20115..20981
                     /locus_tag="OE968_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YncE family protein"
                     /protein_id="HCP7218754.1"
                     /translation="MKIYISNYLSKSISIVDYSTLELEKEIVLEDNIYPHHFCIEKEK
                     NLIYIPSSSNGILYVLDLSNDKIIDTVSIGGSLSQVVLSDNELFVANEDSNSIYVLDK
                     NTLNPIGIIGVDNMPHGFDFDRESKKLYVPCINSIVCIDTINKNIQKKINMDFRAWHI
                     ELDKQKKEMYISTLDGKLIIIDEVSMDIKKVLYEFLLPVEIRFNYSGKKVYVADLGYN
                     NVRILDYTTSRYIGNIEINGIPQGLEISKDEKLLFVSDTQENSVKVYETANNKLIKEI
                     KVGKEPTTIICL"
     gene            complement(20985..21521)
                     /locus_tag="OE968_001471"
     CDS             complement(20985..21521)
                     /locus_tag="OE968_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4364 family protein"
                     /protein_id="HCP7218755.1"
                     /translation="MFENSSEELAYHKLLILYILEKIKMDLTNSQITQVVLETEMMNY
                     FSLQQLLSQLMESKFLTTYKDSDREYYALTQRGVESLEYFFNRIPTSVTEKIDKYIDS
                     NKENLLADTQVKSSFVKQSDNEFIVNLRVIENQSNLIDLNLNVSSEKQAKLICNNWKN
                     NASYMYAEVIDLLIRDIH"
     gene            complement(21712..21915)
                     /locus_tag="OE968_001472"
     CDS             complement(21712..21915)
                     /locus_tag="OE968_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta-type small acid-soluble spore
                     protein"
                     /protein_id="HCP7218756.1"
                     /translation="MSNSNRTVVPEAKAALNQMKLEIANEIGLSNYENIDKGNLTARE
                     NGYVGGYMTKKLVEMAERQMAGK"
     gene            22206..22970
                     /locus_tag="OE968_001473"
     CDS             22206..22970
                     /locus_tag="OE968_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HCP7218757.1"
                     /translation="MKREVKRTKALIYSVLFFSLLLVLIFVFVYGIKYICSKSDNSKM
                     PIYKVDTNEKKIALSFDVAWGTDNMDDILKILDKHNVKATFFLVGSWVDDNEEIVKAI
                     DEKGHEIGNHSNTHANLKEISKEDITKEIETTSEKIYNITGKRTNLFRPPFGDVNNKA
                     MDICSDLGYKVIKWDVDSIDWKELGPNHVIEKVIKESQPGSIVLFHANINDVDNYLDT
                     IISRLKKDGYSLVKISDLLYKDNYVVDSNGVQKTKN"
     gene            23359..24672
                     /gene="prdC"
                     /locus_tag="OE968_001474"
     CDS             23359..24672
                     /gene="prdC"
                     /locus_tag="OE968_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline reductase-associated electron transfer
                     protein PrdC"
                     /protein_id="HCP7218758.1"
                     /translation="MNKLYSILLKQHVGGPDKPVVSVGDVVKKGTLIAEPTGLGANIY
                     ASVSGKISEINDQAIVIEADEVQEDTFEPLKGEGILDLIKEAGVVGMGGAGFPTHVKL
                     NIDLNGGTILANAAECEPLLAHNIKEIEERPEIVYQGIKYAMEVTNAGKGMLAIKSKH
                     PKAIEAFKKVIKPGDNIEVAELVDMYPMGEERAIVRDVLGKLLEPTQLPSEANAVVIN
                     VETLTRIVEAVEQKRPVISKNITVVGQLNSGKESIVFEDVPIGTTVGELIERAGGIKG
                     EYGEIILGGPFTGKATTLDAPITKTSGGIIVTMPFVNEKRKMGLLVCACGPNEERMRD
                     IATKMGVTDIVSVQKCKQAQEIKGALKCENPGHCPGQAQKCIEFKKAGAEVILIGNCT
                     DCSNTVMGSAPKLKLGVYHITDHVMRTVNHPLIRRIKGDVRLKIK"
     regulatory      25076..25161
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
     gene            25743..27992
                     /locus_tag="OE968_001475"
     CDS             25743..27992
                     /locus_tag="OE968_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-Gln thioester bond-forming surface protein"
                     /protein_id="HCP7218759.1"
                     /translation="MKTKIKKSSIISLVIAFSMVFTAFTPIVSYADEVTSNDTILNGE
                     EQSNGQTSDVEKPSDGQVPDGEKPSDSQVPDVEKPSDGQVPDGEKPSDSQVPDGEKPS
                     DGQVPDGEKPSDGQIPDGEKPSDGQIPDGEKPSDGQIPDGEKPSDGQMPDGEKTSDSQ
                     TPDVEKPSDGQMPDGEKPLDEQTPEEEKPLEEEIVIEEMSLKQDIDKILDMTLSQINK
                     IVYNFWEDEEDVKADEQSEINQVFTSEDSFISLWYDKKAKVKNSCLLKEIDGSDRPYH
                     DLRFDDITKTLTFDYVIKGLVGASSKDDKYVIEGEDGEQTAFCYNNHLRPPSSNGKSP
                     YLPAEDFNGQENQNEEAVKSILYAGSEFDGFGYKQQFNLGGEENELMTYSATQSAIWI
                     ILGQMDEQERLKQYQGSINLCDKLIERAKTEEERAEYQKKKEVAINIKAYLEALLKAG
                     REELKPNNTGKPSLSNGLTKINFEKNEDGTYETEAVALVGYSGVVKLKLPDGVTAYDG
                     DGNIIGTGEVEISTQQKFKLKSVGKPDAKANISAVSYDYIFPKAIQYYKAVLDLGQKD
                     HSSSLPSSKQNLLSYTIEKKNGQEVNFNIGLPTDDDDVVNPPVPPIDDDVVNPPVPPT
                     DDTNGHKPKPSPPIDDTVINPPVPPMDDTIINPPVPPTEDAVLNPPVPPMEDAVLNPP
                     VPPTEDTVLNPPVPSVSDTVEKTPELSRDDTIIKSPKTGDETQLMSYVFISVIAICGL
                     AYQCKIKRN"
     gene            28399..30159
                     /gene="prdR"
                     /locus_tag="OE968_001476"
     CDS             28399..30159
                     /gene="prdR"
                     /locus_tag="OE968_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54 dependent transcriptional regulator
                     PrdR"
                     /protein_id="HCP7218760.1"
                     /translation="MFSIPEVKKVEEVMDTKFTTIDEDTRIEDAIKEMIKSNTKTLMV
                     IDSSDQLKGIISMTDIHNLYEMHKKYEGQPVKLIMKKDVIYVNEGLTLDECRDIMILK
                     NIGILPVLRDNKIIGVLKQEHIRDYLYMHLEDYGLTLKYIIGQIKEGICAINNEGVVI
                     LWNKFMEERYDIKSEDIVGRPMNEFLENTISEKVLNSKVGMSDLYFTDKKENMYALVH
                     ANPIFYKEEFIGVVCTEVDVTEAKILALELEKVNDTLKYLKNEVKNLSKGSFDKILGK
                     SYKLEKSKAIAKQVARTNSSIFIWGESGTGKEVFARAIHDYSERKGQFIPVNCSAIPN
                     ELFESEFFGYESGAFTGASKKGRIGIFELAKDGTVFLDEIADLPLSMQAKLLRVLQEK
                     EIRRVGGDTTIKINPRIISATNKDLSKMVKAEKFREDLYYRLNVVEIKIPPLRERKED
                     IGLLVHSFLEEICKQNNKPVLTISKDVIDIFQNYRWKGNIRELKNTIENIVVLSQNSK
                     IDVDDVPSYMMDSTNNSTEEEEYPLDLTKATQKIEIKNITKALKMSNGNKAKAAKILN
                     IPRTTLYYKIDQYKIDVSKI"
     gene            30588..32468
                     /gene="prdA"
                     /locus_tag="OE968_001477"
     CDS             30588..32468
                     /gene="prdA"
                     /locus_tag="OE968_001477"
                     /EC_number="1.21.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-proline reductase (dithiol) proprotein PrdA"
                     /protein_id="HCP7218761.1"
                     /translation="MSITLETAQAHANDPAVCCCRFEAGTIIAPENLEDPAIFADLED
                     SGLLTIPENGLTIGQVLGAKLKETLDALSPMTTDNVEGYKAGEAKEEVVEETVEEAAP
                     VSEAAVVPVSTGVAGETVKIHIGEGKNISLEIPLSVAGQAGVAAPVANVAAPVASAAA
                     EVAPKVEEKKLLRSLTKKHFKIDKVEFADETKIEGTTLYIRNAEEICKEANETQELVV
                     DMKLEIITPDKYETYSEAVLDIQPIATKEEGELGSGITRVIDGAVMVLTGTDEDGVQI
                     GEFGSSEGELNTTIMWGRPGAADKGEIFIKGQVTIKAGTNMERPGPLAAHRAFDYVTQ
                     EIREALKKVDNSLVVDEEVIEQYRREGKKKVVVIKEIMGQGAMHDNLILPVEPVGTLG
                     AQPNVDLGNMPVVLSPLEVLDGGIHALTCIGPASKEMSRHYWREPLVIRAMEDEEIDL
                     VGVVFVGSPQVNAEKFYVSKRLGMLVEAMEVDGAVVTTEGFGNNHIDFASHIEQIGMR
                     GIPVVGVSFSAVQGALVVGNKYMTHMVDNNKSKQGIENEILSNNTLAPEDAVRIMAML
                     KNAIEGVEVKAPERKWNPNVKLNNIEAIEKVTGEKIVLEENEQSLPMSKKRREIYEKD
                     EN"
     gene            32549..32833
                     /locus_tag="OE968_001478"
     CDS             32549..32833
                     /locus_tag="OE968_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218762.1"
                     /translation="MDRLKYISSETFYEGIIVDIKGGGVTIDLKGRLGQFKIPNRMLI
                     TDYELKIGQEVGFMLSYPEVLSPEPNQEYVENIRREKEKQAEMQSKQEEK"
     gene            32871..33596
                     /gene="prdB"
                     /locus_tag="OE968_001479"
     CDS             32871..33596
                     /gene="prdB"
                     /locus_tag="OE968_001479"
                     /EC_number="1.21.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011986824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:33321..33323,aa:Sec)
                     /transl_table=11
                     /product="D-proline reductase (dithiol) protein PrdB"
                     /protein_id="HCP7218763.1"
                     /translation="MSLTTVQGLQSEIFVPITPPPVWTPVTKELKDMTIALATAAGVH
                     LKSDKRFNLAGDTTFRAIPNTATVDEMMVSHGGYDNGDVNKDINCMFPIDRLHELAAE
                     GFIKGVAPMHYAFMGGGGNQHVFTEETGPAIAAKLKEEGVDGVVMTAGUGTCHRTAVI
                     VQRAIEEAGIPTIIIAALPPVVRQNGTPRAVAPLVPMGANAGEPHNIEMQTHILRDTL
                     EQLVAIPSAGKIVPLPYEYKAHV"
     gene            33676..34434
                     /gene="prdD"
                     /locus_tag="OE968_001480"
     CDS             33676..34434
                     /gene="prdD"
                     /locus_tag="OE968_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline reductase cluster protein PrdD"
                     /protein_id="HCP7218764.1"
                     /translation="MEEKIMRRLVIKPFHMNEVNFGSKTSIKKDVLTIDLSSIDEIKE
                     REELITDIKVDIIKPGDYDREINTIMDIIPISTKVLGRLGEGITHTLTGVYVMLTGAD
                     EDGNQMHEFGSSEGILKDQMVFGRYGTPSVEDYIIHVDVTLKGGLPFERTLPLAAFRA
                     CDDFIQEIRASLKMEDGRNATQVREYFDKIRPNAKKVVIVKQIAGQGAMYDNQLFSKE
                     PSGFEGGTSIIDMGNVPMIISPNEYRDGALRAMT"
     gene            34449..34916
                     /locus_tag="OE968_001481"
     CDS             34449..34916
                     /locus_tag="OE968_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline reductase"
                     /protein_id="HCP7218765.1"
                     /translation="MGIGPSTKETSLHHFRDPLLDIVESDKDVDLLGVIVVGTPDGNE
                     NKTFVGQRTAAWLEAMRVDGAIVSSDGWGNSHVDYANTFEEIGKRDIPVVGVTFNGTQ
                     AKFVVSNQYMDTIVDMNKSKEGIETEVVGENNTNEIDAKKALAFLKLKMRKHG"
     gene            34934..35416
                     /locus_tag="OE968_001482"
                     /pseudo
     CDS             34934..35416
                     /locus_tag="OE968_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428088.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="proline reductase"
     gene            35436..36443
                     /locus_tag="OE968_001483"
     CDS             35436..36443
                     /locus_tag="OE968_001483"
                     /EC_number="5.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline racemase"
                     /protein_id="HCP7218766.1"
                     /translation="MKFSRSIQAIDSHTAGEATRIVVGGIPNIKGNSMPEKKEYLEEN
                     LDYLRTAIMLEPRGHNDMFGSVMTQPCCPDADFGIIFMDGGGYLNMCGHGTIGAMTAA
                     IETGVVPAVEPVTHVVMEAPAGIIRGDVTVVDGKAKEVSFLNVPAFLYKEGVEVDLPG
                     VGTVKFDISFGGSFFAIIHASQLGLKIEPQNAGKLTELAMKLRDIINEKIEIQHPTLA
                     HIKTVDLVEIYDEPTHPEATYKNVVIFGQGQVDRSPCGTGTSAKLATLHAKGELKVGE
                     KFVYESILGTLFKGEIVEETKVADFNAVVPKITGSAYITGFNHFVIDEEDPLKHGFIL
                     K"
     gene            36563..37444
                     /locus_tag="OE968_001484"
     CDS             36563..37444
                     /locus_tag="OE968_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TSUP family transporter"
                     /protein_id="HCP7218767.1"
                     /translation="MVAILKALYVVFAAIFAVVFGKDVAKANKEGKLEEQSTPKVAVT
                     GFITDFFDTLGIGSFAPTIAMSKALKLNIPDKKMPGTLNVAHTIPVVTEAFIFTSIIP
                     VDGVTLVSMVVAAAVGSYIGAGIIAKMDERKIQLVMGVTLALTAILMLLGHPWINVLP
                     GGGNELGLTGVKLVIGVIGNFILGALMTAGIGLYAPGMAMVYFLGMSAKVAFPIVMGS
                     CALLMPVASMKFIKEDAYTKKASVIIAICGLIGVFVAAYIVKTLPMDILKALVIVVIA
                     YTSATMIMAANKNKKTA"
BASE COUNT        15045 a         4140 c         6868 g        11786 t
ORIGIN      
        1 ttagtattta ataatgaatc ttaatgttta atacaatatt caagaattat tcaaaaatac
       61 ttaagtatta tagtctagtt tgtaaagata ttataaaata ataataccag ttatatatga
      121 aaataaaaca ttataatttg taataactat aaaacttgga attataatta aaataccttt
      181 gaatggagtg gtgtaatgta taatttactg gttgtagatg atgatgttga tattttaaac
      241 ataaatcaaa tttatttttc taatataggt tttaatgtat atacatcaga gactgctaaa
      301 gatgctatgg atatagtaga gagtatagtt ttagactgta taattttgga tatttcattg
      361 ccagatatag atggatataa aatgtgcaat gatataaaag aaaaggttaa catacctata
      421 atatttttat ctaattatga gcatgaagaa gaaaaagttc ggggattttt agctgggggg
      481 gatgattata taacaaaacc ttatagttta aaagaacttg aacttagaat atatgctcgt
      541 atgaggcagt acaaaaatat tacatcagtt cctaatgtgt taaagttttc agcgttagta
      601 ataaatgtaa attcaagaaa agtaactttt gatggagaaa gtatagattt aactactatg
      661 gaatttgaaa tattattgtt tctagctgag aacaaagaac aagtattttc aaagatagag
      721 atatataacc aagtttggaa aatgcctgat attggagatc aacatacagt gcaggttcat
      781 attgcacaga tgagaaaaaa aattaattct ttaagcaggg agcatcaata cattcaaacc
      841 gtatggggaa aaggatataa gtttgtacca taagtgagat actgtaatta ataaatagtt
      901 cttgttttat ttaatactac tatgaaagag atgtggttga tacaatgaaa aagtataata
      961 tactaaaagg aactctcatt gtattgatag tctctctgct ggcaataaca ggattaaatc
     1021 ttctgtataa atatgataat aaatatacat ataagtctat tagagcaagt aatggaattt
     1081 taactataga taatgatact ttcactaaag gtaaacttgt ctttttgata gatgactggg
     1141 agttttataa tcataaaata tttaaaccga atgattttac agagcaagat ataaaaccag
     1201 aatatgtttt tataggtcaa tatccagatt tttctatgag aaaagggact cagtcaccat
     1261 atgggaatgc tacttatcgt atgagaataa aaaatgaagg caaggataag ctactaagtt
     1321 tagagcttcc tgagattttt tccgcaagtg aagtatggat aaatggagaa atggtttcta
     1381 aattaggaga tgtaggaaca gaaaaatata gacccaaaat taaaaattca gtagtaagtt
     1441 ttattgcaaa gaaaaataca gaaattataa tcaatgtatc gaatttttca cattattata
     1501 gtggtttgta ttatccgcct gcattaggag aaacaaagga cataagtaat atgatgtttt
     1561 atcgattact tttttatagt ataatttgct tcacaacttt tgcaatagct atattttcat
     1621 tgtctgtatg gtttctttca aacaaaagta aaatttactt atattttgga tgtatgtgtg
     1681 ttttctttgc catccatgta tcctatccct ttgtacattt gttaggactg cctttggtaa
     1741 gctttacata tgcggttgaa gatttgtcat attttatggt agttttatgt attatttgta
     1801 taaatggaag tatatccaaa atagaagaaa ataaagtgta tagattttta attttaccat
     1861 taggaattac aatgagtatc atatctatag tgataccaat tattcttctt ccatatgata
     1921 tgtactttgt caacatatat gggaagttaa tagacatata taaatatatt gtatttatat
     1981 atatattaat gtcttcgctg gtttcaatat ataaaaagac atgctctgag catataagtt
     2041 cttatatttt agtttcagta aacactgttt ttggaattag catattattt gatgcagtta
     2101 cgagtaatag atttgagcct atatttacag ggtggcaaac agaatattgt gggtttgtaa
     2161 ttgttatttt attttctgtt atgatgataa acaggaatag aataataata aaagagaatg
     2221 aaaaacttac aaggaatctt gaacatgaag ttgaagtgag aactaatgaa cttacaacat
     2281 tgttaaatga acgtaaaaga ttcttggcag atgtagcaca tgatttaaag gcacctgttt
     2341 cggctataca agcatttata gatttgataa aggttggtaa tattcatgta gatgaagaga
     2401 caagaaccta tctttatgct ataaatcaaa agtcaaatga agtacaaaat agagtacgta
     2461 gtttgcaaga atttacatca caagataaaa gcattggtat tagtgaaaaa atatgtctga
     2521 ataattttat taaagagata tatgaaaata atttgccaga tacacaagca tgtggtgtaa
     2581 actttgaaac ttatgtattg gagaaaaaaa tatatgcaaa gataaataaa gagatgctta
     2641 caagagcatt tgagaattta atttataatg ctttgacctt tactccattt gatggaaaga
     2701 taattttatc aatggataaa gaagatggat ttgcaattat taaaatttct gataatggaa
     2761 aaggtatacc tccagaaaat ataccaaagg tatttgacag attctttaca gaaagagaca
     2821 ataatgagcc aaaagggcaa gggttagggc tatatattgt caaatccatt ataagagagc
     2881 atggtggaga aatatttgta gattcagaac taggaaaagg aactgttttt acaataaaat
     2941 taagtctatg ttttttataa taatagctta tttaatataa aagaataatg atatttggga
     3001 gtgattataa tgcaaactaa gatattgata atagatggag acaaggataa ttgccagaag
     3061 ctaaaaggat ttctggagga aaaaggaata agtatagatt tagcatataa ttgtgaagaa
     3121 gctattggaa aaatatttag caataaatat gatttaatat ttttagaaat aattctaagt
     3181 gatggtgatg gatggactct ttgtaaaaaa attagaaatg taactacttg tccaattgtt
     3241 tatatgactt atataaatga agaccaaagc attttaaatg ctttaaattc tggtggagac
     3301 gattacttaa taaagcctct aaatttagaa atattatacg caaaagtaaa agctatttta
     3361 agaagaatga actcatatgt aaataataat gaaaataata caaaattaga ggaatataat
     3421 agaactagtg gagtaataaa gttagaagat aaaataataa aattgactcc aacagaaaat
     3481 aagttgttaa acttttttat agagaatcct gaaaagactt tgactactaa agagatatat
     3541 gaacatgtat ggatgaatga atacttagag gataactata gtgtggtagt tgcagtgaat
     3601 ggattaagaa agaaaataga gaaagattat aaaaatcctc agaaaattat aacaataaga
     3661 ggagcaggat attattttaa taaggaataa taaatatatt aatatcatta ataattgtta
     3721 taaatgtgaa atactaacga tatctaaact aaattattat aaaatagctg actgtaattt
     3781 aattgataaa tcctattctt ctagactttg ccagttaaat tacagtcagt tttattatat
     3841 aaaaaaatgc gtaatggaac tattatttta tagattatat ttgaaaagat ggataaattg
     3901 tatatctaaa tctatatatt attttattat ttaatatata ttaaataata aaatagttaa
     3961 ataataagat taagaatttc ttaataaatc cagaagatgc tttcgattat ataatatttt
     4021 atatttttat attattaatt atatgtgttg caatcgctgc acctactttt tctggtgagt
     4081 atcagacaca atcagatagc atccttcgtt gtacgaaaca tggacatatt cgtctagcgt
     4141 ttactaaaat attagctcta ttttctatat ttataataat gtttgttata tgtatttcta
     4201 tccatttggc aatttctgat ttagcttttg gtactgaatg tttgaaaacc tcatttcaaa
     4261 tgttgttttc tgtcattagt ctagtaaata taaatttact acaagcacag attcttatag
     4321 ctattggtgg tctaatttca atacttgcaa tggttagttt aacattattt ttatctgcaa
     4381 aatgtaagga ttctcttact tctatgctga ttgctttttc tatttgctta attcctatgg
     4441 gaataggtgt tagttggatt ggatacctat taccaccagg gggaattggt tttaagatta
     4501 gtttattata tcaaatgaca tcatttaatt tcttacactt aggaggtatg agtttttgga
     4561 caccacacat tatactgttt ttctcagtga tagaaatacc tatttttata tttttggcta
     4621 ttcgtaccta ttgcaaacat caagtaccgt aacaatttga tggaaataat agtgatataa
     4681 actagaggat acaataatta tatatgtagt ataaaagtta aatttagtta acaaatctta
     4741 atagcagata taggtaataa attatacata aactgtatta ttatctatat ctgctatttt
     4801 aatatagaga aacaacagta tattgtaaag taaatgtcaa atatagtttt aaaagtaaaa
     4861 ttaatgttaa aaagtaaata taattttaca cttgcttaac ttaatcctaa tatagattta
     4921 acttaaaaaa agtagaataa aagtatagga aatttgatga agacgaatta taaaaaatta
     4981 aattttgaat acagaacgaa aatcgataag tatattttaa tgggagggta ttatgatagt
     5041 aaaatctaga ttagtaggtt tagaaaaaaa tgacaataat ggcaataaga caaaatacgt
     5101 aattgaaaaa gtagcaaaaa atatttttct acttagtgct ttagtagcag ttgcaagttt
     5161 acttttgata ataggattcg tattttataa aggattaaga ccatttatat ttgaaggata
     5221 ttcatttata gactttttaa ctggtgcaga ttgggttcct tctgccaata aatttggaat
     5281 atcatctatg atagtagcat caatatttgc aacacttgga gcacttgtta taggagtacc
     5341 tgttggtata ttaacctctg tatttatagc agaagtagca cctaaaagat tagcaaaaat
     5401 aatgtcacca gcagttgaac ttttagcagg tataccttca gtattatatg gtgtatttgg
     5461 tcttgcagtg atagttccaa ctatacaagg tatatttaat cttccaaaag gtcaaagttt
     5521 gttagcaata gtaatagtat tagcagtaat gatgttacca acaataatat ctgtatcaga
     5581 aacagcaata agagcagtac caaaagcata caaagaaggt tcattagcac ttggtgcatc
     5641 aaaaatagaa acaatattca aagttgtatt acctgctgca aaatctggag tattagccgc
     5701 agtagtgtta ggagtaggaa gagctttagg tgaaacaatg gcagtaatac ttgttgcagg
     5761 caactcacca gttatgccaa ctgcaataac agatagtgta agaccactta caactaatat
     5821 agcacttgaa atgggatacg catttggtac acatcaagaa atgctatttg caactggagt
     5881 agtattgttt acatttatat taattttaaa cttagtttta aataaacttt caaataaggc
     5941 ggtaaattaa gatgagaaag ttcaaagaga atctattgaa gtcattagta tatctatcag
     6001 cactatttac aatagtatca ttagtagtta tagtgggatt tatatttata aagggaattg
     6061 gcaacatgaa ttttaatttc ttatttagca attattcagc atcaggtgat ggtggtatac
     6121 ttccaatgat aattacaaca ttatatacag tagtagtttc tatagttgta gcaactccta
     6181 taggaatatt ggctgctata tatttacaag aatatgctaa aaaaggaaaa gcagttacag
     6241 ctataagatt tgcaactgaa agtttatcag ggataccatc tatagtatat ggattatttg
     6301 gaggaatttt ctttgtagtt acattaaaaa tgggatattc catagttgca ggttcactta
     6361 cagttgcaat aataatatta ccagtaataa ttcgtacaac agaagaagct ttaaaaacag
     6421 ttcctcaagc ttatagagaa tcatcattgg cattaggagc tacaaaattt caaactttat
     6481 ataaggtagt acttccaagt gcaataccag gaattttatc tggagtaatc ttatcagttg
     6541 gtcgtataat tggagaatca gctgcaatat tacttacagc aggtactgta gccaagatgc
     6601 caggtggaat atttgatagt gcaagaacat taactgtaca ctcatactta ctgactaaag
     6661 agagtggaga tatagcaaca gcagccagta taggaattgt tttaatagta attgtattag
     6721 cactaaacat gctagcaaga tttgttgcta agaaattaaa taaagctaat tattaaattt
     6781 aagaggtgtg aataatggaa ttaatcgata agataaaaat gagtgtaaaa gatttggatt
     6841 tattttatgg tgataagcaa gcattaaaga aaataaatat ggatataaaa gagaataagg
     6901 ttactgcttt aataggtcca tctggatgcg gaaaatcaac ttttataaga acgttaaata
     6961 gaatgaatga cttaatcgaa gatgtaacaa ttaaaggaaa catttctgtt gatggagagg
     7021 acatatatac ctcagatgat gttataaatc ttcgtactaa agtaggaatg gtatttcaaa
     7081 agccaaatcc atttcctatg agtatatatg ataatgtggc atatggtcct cgtacacatg
     7141 gactaagaga taagaagcaa ttagataaaa ttgtagaaga aagcttaaaa ggtgcagcta
     7201 tttgggatga ggttaaagac aggcttaaat catctgcact aggactttct ggtggtcaac
     7261 aacagcgtat atgtatagca agagcaattg ctatgagacc agaagttatt cttatggatg
     7321 aacctacatc tgctttagac ccaatttcaa cattaaaagt agaggaactt atagaggatt
     7381 taaaaaaaga ctacacaata gtcatagtta cacataatat gcaacaagct gctcgtatat
     7441 cagatgaaac agcttttttc ttaaatggag aggttataga atttagcgat acaaaaacta
     7501 tgtttaccac tcctgtagat aaaagaacag aagactatat aacaggtaga tttggttaaa
     7561 atatataact ataaaggagt tagacaatgg tcaataatag tttagatata agtattgata
     7621 ctttaaaaga acaaacagtg cttatgatgg aaaaatgtga agaagcaata gaaaagtctg
     7681 tgacttgtat gatagagaag gatttagagg gtgcaagaaa agtagtagaa gatgatgaag
     7741 aaataaataa attaagagaa gaaataagag ataagagtat agagctaata gtattaaagc
     7801 aaccaatggc aagggactta agatttattt attcattagg taatatatct atagagctgg
     7861 aaagaatagg agattatgca gcaaatatag ctagagaaat gttgaagata ggtggagagg
     7921 cttatataaa agagctaata gatattccta agatggcaaa agaatgtaag tctatgatgt
     7981 ctcagactag agaagcttta atcttatttg atgcaagtat agcttatgat gttggaacta
     8041 aagatgatat tgtagatgga ttgtatgaac aagtacaaat tgattgttta aaaataatgc
     8101 atgaaaactc aaataccata gaccaagggg taaaacttct acttatagga agataccttg
     8161 aaagaattgg agaccatata acaaatgtat gtgagaagat aatttttgca attgagggta
     8221 aaatggttga gataggataa aaaactgctt taaagcagtt tttttattgt ctaaattaag
     8281 aaagaattga taaaaaaata tgattaatgg gtaaatttaa aaaattgtga tatactagga
     8341 acatattaaa tatgaggatg cgtattttat ataaggtgct ttttaggagg tggaactttg
     8401 aaacttcaaa agatgggtat gaggactata aaaacaggaa ttagtgtcac tttatgtatg
     8461 attcttggtg actatttagt agagaatatg ttttattctc tggtagcatg tataatttct
     8521 gttcaagata cagtaaaagg ttctttaaag acgggaatca atagagtgga aggtactatt
     8581 ttaggtggta taataggatt catatttgca atcattaaag ctggagaccc atttttatgt
     8641 ggtctaggag taatgtgctc aatatattta tgcaatctgt ttaaaataaa gtcagtagta
     8701 gttgcctgtg taacctttct ggctatacat ctaggtgtag gaaatagtga ccctgtgtat
     8761 tattctttac atagggtgtt agatacatct gtgggtgttt tgtttggagt acttgttaat
     8821 tattatgttg ctagaccaaa ttatctaaat agtgttatag atgagtttaa aaagatagaa
     8881 gaactttcaa tgttgcttat tgaagataaa attcttagaa aagaaaattt aaatgtagag
     8941 aaatttgaag aagaagtaga aaaattagaa gaaatatatt caaaacttat tgatgagttg
     9001 gattatagtt tgagtgaaac taatatagaa aaaattgaga atgccttaag gatatgtaga
     9061 gaaatacatt ttcatatgca gtctatagag ttacttgaaa ataaacttta tttgaaagag
     9121 catacatata aataccttaa gaaaacatat aatgtggata agctagactg gaatatagat
     9181 gaagaaaaaa gccctgtatt caactatcat ctaatgaaaa taatgattga aatagagttg
     9241 ttgagaaagc taaataaatc atattaataa tagtagttaa ataataaata aaaaatagta
     9301 tctttgtaaa tattaaacat atataagttt aatttatgga ggtactattt tttatgaata
     9361 ctagaaatga caattctaaa atactagaaa tatataaaat gaagcttttt ggcgaacttg
     9421 taaaagcagt gtggaatgat gatatagagg atattgaaaa cttacctaat aaaattttaa
     9481 atgaagattt aaaggataat ttaaataatt attttagtgg aaaatttgat aaagatacta
     9541 tggtaaattt aattagggta actatgggat tggatgttac agaagataca gataaaaatt
     9601 taaaagagtc actgcatgaa gctgtaaatt tagatgaagt caaaagacca ataatatctg
     9661 taatatcaga tgcttgcaaa tattgtgatg aaaataataa ggaagatgag tcatgtaaga
     9721 taagaagtaa gcatattaat tgtaatgagg aagatgtatg tagtgcttgt ggtgattgtg
     9781 tatcaagatg taagttgggt gcaatttcag ataaaataga atttatacca atgataaaat
     9841 tgttaaaaga tataaagagc cctgtatatg caatagttgc accagctttt gtaggacagt
     9901 ttgggaaaga tgtaagccct ggtaaattaa gaactgcatt aaaaaagata ggatttgaag
     9961 atatgataga agttgctttg gcagcagata tgcttactgc aaaagaagca tatgattatt
    10021 atgagcatat gaaaaaggac gaagaaggat gctttataac tagttgttgc tgtcctattt
    10081 gggttagttt gatacaaaat agttttcctc agatattgga aaatgtatca ccatccgttt
    10141 ctcctatgat tgcttgtggg agagctgtaa aaattttaaa tccagatgct aaagttgtat
    10201 tcataggtcc ttgtatggca aaaaagaaag aagcaatgtt agaagatata aaagatgcag
    10261 ttgattttgt gcttacattt aaagagttgc aagaaatatt tgatgcatta gagttaaatc
    10321 cagcaataat ggatgagagt aatagagtag aggcgtccct ttcaggtaga gtttatgcta
    10381 gaacaggagg tgtaagtaaa gcagttaagt tatcagttag aagaattgac aaaaatataa
    10441 aatttgaaga aaaggcattt gaaggaacaa aagagtgcat ggacggtcta aagaaagttc
    10501 taaataaaga aatagaagct acatttatag aaggaatggg gtgtgtagga ggctgtgtag
    10561 gaggtccgaa gcgtatttta agtgtggaag aaggtactaa gaatgttgat gaatatagtg
    10621 aaagtacgaa tatggaaact ccatttgata atttaaatgt attacaattt ttaacttctt
    10681 tgggaatcaa aagagtagaa tctttaggag aaaaagaaga agaaaaggtt aaaaaaatat
    10741 ttagtagaga tataaaaagt aataagaaag agaataaata taaaaaataa ctttttaagt
    10801 cttaaactta tgcttttata aaagggagat atgggggatg aaaattaaag ataataaggc
    10861 tgtttttcat gtatttataa ggatatttct tatagctgtt ttaattttaa ctggaacatt
    10921 attggaggaa aaaattaata atgttccagt tgaaaatata agttcaaaag gtgaaaatac
    10981 actggaactg ctttctcaaa gtaatacttt aggagaaatc atatacaaag catctcaaga
    11041 agaaacaaaa ggtccagggg ctacttctga aaaagtagca tacataacaa tagatgatgg
    11101 tccatcaaaa tatacaaatg cactacttga tattttaaaa gaaaatgatg tcaaagcgac
    11161 atttttcatg cttaatcaga atatgaaaaa ccacaaggaa gaagtaagga gagtcttgga
    11221 agaagaaaac tcaataggtt ttcatagtgt aagtcatgat atacataagt tatataaaag
    11281 cccagaagta acagttgggg aatttaatac atgcaataat actctacaag aaataactgg
    11341 tcagagttca aaattaataa gattaccata cggaagtaaa ccatatatgc cagaaggttc
    11401 atataataaa cttatggcaa atgattattt aatttgggac tggaatttgg atacacagga
    11461 ttggaagtct tctacaagtc agatagtaag taatatatta tattatggaa gaaaaagaga
    11521 tgaattagta gtattaattc atgagaaaga gcaaagttta aatgctttaa ataatattat
    11581 aagaatctta aaagagagag gatatacaat attgccaatt acagaaaata taacacctaa
    11641 aaatttctgg caagaaaact tataataaat ttaaatatag taaaagataa agtaaattat
    11701 ttataaaata aaacatataa tataaaaaat acgaataaga ggtatactgt aaggataata
    11761 taaaattaat gagaaagcat taaaattaaa ataaaataat cttgcaatta ttgacattat
    11821 aagacagaat aactgtaaaa acatatttta aaatataaca actatataaa agagaataga
    11881 cataattaag aaaattcaga aaaaataaaa taaaaataat tgacaaagag aataatattt
    11941 gtatataata atatgtaata ttaaagactg agaagaagag gagtaagtaa atactactaa
    12001 aagagaggaa aattcactgg ctgtaagatt ttctaagtat aagatttact gaatgtagct
    12061 ttggagtttc taaactgaac tataagtaag tttagacggt tagaaccgtt aaattctttg
    12121 agagtcaaag ttgataaaat aacattaacc aataatttaa ttatatgtta atgtatttta
    12181 agctttggaa ttaaggtggt aacgcgagct tttcgtcctt tttaaagagg atgaagagct
    12241 cttttttatt tctaaagata tttaaaaaat ttatttataa aatacaggag gcaggacaat
    12301 ggaaaatacg aatttatcaa aaacttataa cccaaaagat tttgaggcta ggctatataa
    12361 aaaatggatg gatgaagggt attttaaatc taaaccaaat ccagataaaa aaccatttac
    12421 aataatgatg ccaccaccaa atataacagg gcaattgcat atgggacacg ctcttgacca
    12481 tacacttcaa gatatattaa tcagatggaa acgtatggat ggatatgaag ctttttggct
    12541 tccaggaact gaccatgctt ctatagcaac agaagttaaa gttgttgaaa gaataaaaaa
    12601 acaagaaggc aagacaaagt atgaaatagg tagagaagaa tttttaaaga gagcctggga
    12661 atggaaagat gaatttggag gaaaaatatc taatcagctt aaacaactag gtgattcttg
    12721 tgattgggat aaagaaagat ttactatgga tgaagggtgt aatgaagcag ttatagaatt
    12781 ttttgtaagc ctatatgaaa aaggtcacat atacagagga aatagaataa taaactggtg
    12841 cccagattgc aaaactactt tatcagatgc agaagttgaa catgaagaac acgacggaaa
    12901 cttttatcat ataaagtacc cactaaaaga tagtgaagac tttttagaaa tagctacaac
    12961 tagacctgag acaatgatag gagatactgg tatagcagta aatccagaag atgatagata
    13021 taaacattta ataggaaaaa cagcaatact tccattagta ggaagagaac ttccaatagt
    13081 tgcagatagt tatgttgatt tagagtttgg aactggtgca gttaagatga ctccagcaca
    13141 tgaccctaat gattttgaag taggattaag acataatctt gagcagttaa atactatgaa
    13201 tgaagatgga actatgaatg aagtttgtgg aaaatatgaa ggtatggata gatttgagtg
    13261 tagaaaagct atcgtagcag acttaaaaga acaaggttac ctaattaaga taaaagagca
    13321 taatcataat gtaggaactt gttatagatg ccatacagta gttgagccta gattatcaga
    13381 gcaatggttt gttaagatgg aagaacttgc aaaaccagct atagatattc ttaaaaaagg
    13441 agaattagaa tttgttccag ataaatttga taaaacttat ttacaatggc tagaaaatat
    13501 aagagattgg tgtatatcaa gacaattatg gtggggtcat caaataccag cttattattg
    13561 tcaagagtgt ggagaaatag tagttgctag aaaaatgcca gataagtgtc ctaaatgtgg
    13621 aagcactcat tttaaacaag atgaagatgc cttagatact tggttcagtt ctgcattatg
    13681 gcctttctct actctaggat ggccaaataa gactgaagct ttagattatt attatccaac
    13741 aagtgtactt gttacaggat acgatataat attcttctgg gtagttagaa tggcatttgc
    13801 aggtatgttc tgtatgaatg aaaagccatt tgaccatgtt ttggttcatg gattagtaag
    13861 agattctcaa ggtagaaaaa tgagtaaatc tttaggaaat ggtatcgacc cattggagat
    13921 aatcgagcaa tatggagctg atgccctaag atttacatta acaactggaa attccccagg
    13981 aaatgatatg agattctata tggaaagagt agaatttgct agaaactttg caaataagtt
    14041 gtggaatgca tcaagatttg tatttatgaa tattgatgaa gatataatta aaaacatgac
    14101 tagagaaagt gttaaagagg acttaactct agctgataaa tggataatat caagagcaaa
    14161 taatattgta aaagaagcaa ctaataacat ggataagttt gatttaggaa tagcacttca
    14221 aaagatatac gattttactt ggtcagaata ctgtgactgg tatattgaaa tggttaaacc
    14281 tagattatat ggggaagatg caaatgctaa atctgcagca ttatatacat taacttatgt
    14341 tcttgaaaag atattaaaat tattacatcc atatatgcca tttataacag aggaaatata
    14401 tactcatctt cctactgttg aaggatgtat aatagtatct gaatggccaa aatataatga
    14461 agaagataac atggctgaag aagaagatat gatgaactta ttgatggaag gtataagaag
    14521 tataagaaat gtgagagcag aaatgaatgt accaccttct aagaaagcta aattgataat
    14581 aatcccaagt gaagaaaaaa tagaagctat tgagcttggt aaagactatt ttataacttt
    14641 agcatctgct tcaaatgtag agatagcaaa agataaatct aatgttccag aagatgcagt
    14701 tggagtagtt attgatggtg ttgaaatatt tatacctctt aatgaattag ttgattttga
    14761 aaaagaaatt gagagattat ctaaagaaaa gaaaaagtta gaaggcgaaa taaagagagt
    14821 taatggaaag cttgcaaatc aaggtttctt agcaaaagct cctgaaagtt taattgaaga
    14881 agaaaaagca aaaaaagaaa aatttgaaga gatgattaaa tctgttgagg aaagattaac
    14941 aaatttagaa tctaaaataa aataaatata agaattagta aaaacataca aaaagtatat
    15001 attctatact ttttgtatgt ttttctttat atatatacaa atatgatgtt ataattcttt
    15061 acagatgtgt tatattttta ttttatgttg tgaatatatg aattttatgt cttaaaattt
    15121 ataagcaata aaaatttgat atattatgat gtttaatata gggtaataaa tacatattat
    15181 atttatttta ctatattttt ttacataata tatctagaaa agtataggaa tttatcgtaa
    15241 tttaagttta aatattaaag agaatttcta taagtagttt aatcgacaat ttaaatttat
    15301 aaagaaattt aaatttgaaa gctagtgagt acagtttgga aattgaaata aagtaaacta
    15361 aatgatattt tagatttgga ggtgatatta tgttcagggt agttatatgt gatgacgaaa
    15421 aaatacaaag aagcatacta aaagagttta cagaaaaact tttgtctgaa agatgtctaa
    15481 attatcaaat actggaattt tcctgtggag aagatttaat atccaaatac ccagaaaaaa
    15541 ttgatattat atttttagat atccaaatga aagatatcaa tggaattgag gtggctaaaa
    15601 aaataagaaa gtttgatgaa aaagtagaaa ttatatttac aacggctttt tcagagtatg
    15661 ccccccaagg ttatgaagtt cgtgcttata gatatttagt aaagcctata gagtatagta
    15721 actttgcaat gggtgtaaat ctttgtattg ataaccttca aagaaagaag gagcgttata
    15781 tagttttaaa tagtaaaaaa ggatttaata gaatactgat agattctatt ttatatgttg
    15841 aaactgtaaa gagagattta gttgtacata caataggtag agattataaa gctaatatga
    15901 gcatgaaaca agcagaaaaa ttactgtgtg aaaatggctt ttttagatgt catacaagtt
    15961 ttattgttaa tttaagaaga atagaagatc ttagggataa tacgattact attaatgaac
    16021 aatttatacc tataagtaag tatagactta aagatttaaa agtagcatta acaagcttgt
    16081 tatgtgatat aatgtattaa ttttaaaaag gtaattgaaa atatcgtaaa aaagatttaa
    16141 tgtcatcaca gggctattga ttgaaactgt cttaatatat aaaatgttat ttatattaag
    16201 acagttttat tatgcaaaat agcagtttat agacttttaa tatggtttaa tatgtatatg
    16261 tagagtttcc attataatag catgattatt aattagtagc ttgattatca atatactatt
    16321 attgattttt atatgtatta tatgtatttt tagaatatga ttaccttttt aaaataatga
    16381 ctatttataa aactctatag atatttgttt catttagcta tgcatacttt aattaattat
    16441 attaatattt aatggagtac aatataaata ttaaagcgac atcttatagt ttattgaacc
    16501 tatagtaatg aattaataaa tagtttaatt ctatgaaaag atttcctttt atgcaattta
    16561 tttattgaaa tatgatataa tatataaagg tgtaagtatt agttgttaaa ataatattta
    16621 tattagtttt tatgcatact tggtataagt ttttcatata ttgattaaaa ttgatgttga
    16681 tttattattt ttagtatttt ttcacctttt gattcatact ttgtagaatg gtgtattttc
    16741 taaaactgat tataagacaa gttcattcaa attagcattt ttatatcata taaataattg
    16801 ttccccctaa ataagattta gatgtatagt attaaaatca aaaagtataa aataaaattg
    16861 atgcttaatc atagataaat attaataaaa tatacaaggg gattgtctaa taaaaagata
    16921 atctcctttt ttacaaataa ttctaaattg tgatataaat ctaaaaattt tatcttaaca
    16981 tttaaccatt taatgataat aattgatata ataaatataa attaaatata tggtgtactt
    17041 attttatgtt tttagcaaga aatatagcat ttaaaagata aattgtgcaa cttaaatcaa
    17101 agtttaagat gaactattaa catagatata ttaaaaactt ttgtaatgga gaatatatgt
    17161 gatatgaata ataaagttaa ggttgcagta ttagatacag gaatagacaa agaacatgat
    17221 tacttaaaag ataatttagt tggaggaatt gcttttgaat gtatgcatga ttatatcttt
    17281 atatcagata aatttgatga tgaagatggt catggaactg cttgtgcatc aataataaag
    17341 aaagagtatg aagatgtaga gttatttgta ataaaaattt tgagaaaaga tggtattaca
    17401 aatataaaag ttcttgaaga agcattaaga taccttttag acactaacat aagattaatt
    17461 aatttaagtt tatcagtcat aggagtagaa agtgttaagg gcttatttga agtttgttat
    17521 gaattgttta gaaaaggaaa aataatagta tgttcactcg ctaatgattt tgacttaagt
    17581 tatccagcta tgtttaacaa tgttataggt gtaagaggat ttactttaga tggagatgat
    17641 tcattttggt acaacaaaaa atatgatgtt caatgtgtta tggatagcaa ttcatatata
    17701 agttgtgata taaataattc ctatagatta ccaccaaaat gtaatagtta tttatcagca
    17761 aagcttactg gtaaaatagc taagatatta tcagaaaaac caggcataac aatatctgat
    17821 ttaaatgata agcttgaatc attagcaact agaaatcatt gggatagttg tgattttgat
    17881 gagtgtagta gaattgtaaa ctttaaattg gatttgtatg acaaagaaaa tgctcttttt
    17941 atgaaagttg ctgacgttgt tagggattgc ttagatattg aagagaataa tgaaaaactc
    18001 tttaagggta gcctttttaa taaggagata ggcttggttt atgataattg ttttaatctg
    18061 ttgaaaaagc tagagcatag atttgacata aagtttaatt atatggacat ctcaaaatat
    18121 gacttagttt caatatatac actgactgaa ttagtggaaa gatataaaaa cttataaata
    18181 aagatttgta gctaaattta atgtagaagg tattaaatta tatgtattct ttgtcggtag
    18241 attaaaagta aaaaatatac tataattaga tagcataaga gaaaatgcca atacaggggg
    18301 agttagataa tgaaatatga agaagcatta gagtacatat cacaaactaa taaattcggt
    18361 ataagattag gattagaaaa tatcggaaag ttattagaat tattaggaaa tccacaagaa
    18421 actttgaata taatacatgt agctggaact aatggaaaag gttctgtgtg ttcttttgtt
    18481 tctaatatac taagagagtg tggatataaa gttggtttat atacatctcc atatttagaa
    18541 acttttactg agcgtataag agtaaatgga caaaatatac cacaggatga tgttgctaga
    18601 ataattgagt taataaaaga aaaaatagag attatggtaa aagaaggcta tgcatatcca
    18661 acagaatttg aagtggttac tgcaatggca ttttattact attcagaaca aaaggtagac
    18721 tttgtggcat tagaagttgg tttaggtggc agatatgatg ctacaaatat aataacaaaa
    18781 tcacttgtaa gtgtgatagt atctataagt ttggaccata caggtatact tggagataca
    18841 atagaaaaaa tagcgtacga aaaggctgga ataataaagg aaaatggagt agtactagta
    18901 tatgaccaga ctgatgaagc aaaggatgtt ataaagtcag tttgtaaaga gaaaaaagct
    18961 aaatatatag aagttgattt tgatgatata aacataaaaa aatcagatat aaattctcaa
    19021 atatacgatt gtactgtaat gaaagaaact tatagagacc ttgaaataaa attgataggc
    19081 gaacatcaaa taaacaattc tatcttggca attagtgtaa taaaatatct aaaagacata
    19141 aataaattag caaatataaa tgaagaatct ataagaaaag gacttataaa tactaaatgg
    19201 ccaggaagaa tagaaaagat aaaagaaaat ccaattttta taatagatgg tgcacataat
    19261 gaagatggag caaaatcttt ggcaaaagca cttgataaga attttaaagg tagaaaatta
    19321 accttattaa taggtatgtt agaagataaa gatattgata gtgttttaga gatattgttg
    19381 ccacatttta ataaggtaat aacaacaaca ccaagtaacc caagagccat aaattcagat
    19441 atattaagag aaaaagtatt aaaatatgta gatgatgtaa catcaaagca tgagatagag
    19501 gatgcagtaa attatacatt agaaacatca agtgaggatg atattataat aagtgcaggt
    19561 tcattatata tgattggtac agtgagaact ttagtaaaga aattataatt ttataaaata
    19621 agtatacaaa taaaaatata aaaaagagtt gtctaaaaaa tggacaactc tttttatata
    19681 aaataagttt ttaataattt tactgatgtt tatataagta attatataga ttgacgtata
    19741 gctttagata attggtctgg gcaagaagta ccttttccac cacagtcaat accatttaat
    19801 ttatcagcaa cttcaagagc attttggcca attattaagc ttctaagtcc tgataaatta
    19861 ccattacatc ctcctataaa ttcagcatca acaatcacat tattttcatc aacttcaaaa
    19921 atcatttctc tacaacatac accacttgga ttaaatgtta ctttcattaa aaagacctcc
    19981 attaaatatt atttcttttt ttaacattaa taataatacc aaatatatgc gtaataatgc
    20041 aactataaag cataatacaa gctaatgaaa taatatatta ttgtagtata tgtattgtag
    20101 agaggagggg ttatatgaaa atctatattt ctaactactt atcaaagagt attagcatag
    20161 ttgattattc tacacttgaa ctagaaaaag aaatagtatt agaagataat atatatccac
    20221 accatttttg catagaaaaa gaaaaaaatt taatatacat acctagttca agtaatggga
    20281 tactctatgt cttagattta agtaatgata aaataattga tactgtctct ataggaggaa
    20341 gtcttagtca agttgtactt agcgataatg aattgtttgt ggcaaatgaa gattctaata
    20401 gtatatatgt actagataaa aacacattaa atccaatagg aattattgga gttgataata
    20461 tgccacatgg atttgacttt gatagagaaa gcaaaaagtt atatgtaccg tgtataaact
    20521 cgatagtatg tatagataca attaataaaa atatacaaaa gaaaataaat atggacttta
    20581 gagcttggca tatagaactt gataaacaaa agaaagaaat gtatatatca acacttgatg
    20641 gaaagcttat aataatagat gaagtaagca tggatataaa aaaggtatta tatgaatttt
    20701 tattaccagt agaaataaga tttaattata gtggcaaaaa agtttatgtt gctgatttgg
    20761 gttataataa tgtaagaatt ttagattata caacgagtag atacattgga aatattgaaa
    20821 taaatgggat tccccaagga ttagaaatat ctaaagatga aaagttacta tttgtatcag
    20881 atacacaaga aaattcagta aaagtttatg aaactgcaaa taacaaatta ataaaagaaa
    20941 tcaaggtagg aaaagagcct acaactataa tttgtttgta ggctttaatg tatgtctctt
    21001 ataagtaaat cgataacttc ggcatacata taagatgcat tatttttcca gttattgcaa
    21061 ataagttttg cttgtttctc tgatgaaaca tttagattta aatctattaa gttagactga
    21121 ttttctatga ctctaaggtt gacaataaat tcattatcac tttgttttac aaaactagac
    21181 tttacttgag tatctgctag tagattttct ttgttagaat ctatatactt gtctattttt
    21241 tcagtaacac tagtaggtat tcgattaaag aagtattcta gactttctac gcctctttga
    21301 gtaagagcat aatattctct gtcagagtct ttatatgtag tcaaaaactt agattccata
    21361 agctgagata aaagctgttg taatgaaaaa taattcatca tctcagtctc taatactact
    21421 tgagttattt gagaattagt taaatccatt ttaatttttt ctaatatata taaaattaaa
    21481 agtttgtgat aggctaattc ttcagacgag ttttcaaaca taaatatcat cctccgtcaa
    21541 actatttcta tatataatat attaaactaa tttgtacaaa attaaaagaa caatttgtat
    21601 tgtattatta atctttaata attcatataa aaacaatttt ataaataaat atagaaaaac
    21661 agggctgcta attagcagcc ctgttgatac ccaggtgtca aaatttacta tttattttcc
    21721 agccatttgt ctttcagcca tttcaactaa tttcttagtc atatatccac caacatatcc
    21781 attttctcta gctgttaagt tacctttgtc tatgttttca tagttagata aacctatttc
    21841 gttagctatt tctaatttca tttggtttaa agcagctttt gcttctggaa ctactgttct
    21901 gtttgaattt gacatagtaa atttcctcct caaataatta gtttatgatg tctaacaaca
    21961 cttttattta tgtgatgtta atactaattt ctccaaaata aaaataatat atacagaaaa
    22021 ataaaggtaa aaatgtaaaa aatataaaaa aattaaataa atgagtattt tagagagttt
    22081 aattaggtca atataggttt tattttttta gttattgtct tataaattaa atattacagt
    22141 acttttttga gctgaaaaaa aataaatttt aaatatagaa gaaattattt caaaggggga
    22201 atagtatgaa aagagaagtt aaaaggacta aagctttgat atatagtgtt ttattttttt
    22261 cattattatt agtgttaata tttgtttttg tttatggaat aaaatacata tgttctaaat
    22321 ctgacaattc aaaaatgcct atatataaag ttgatacaaa tgagaaaaaa atagctttga
    22381 gttttgatgt agcatgggga actgataata tggatgatat tttaaaaatt ttagataaac
    22441 ataatgtaaa agcgaccttc tttttagttg gtagttgggt ggatgataat gaagaaattg
    22501 taaaagctat agatgaaaaa ggacatgaaa ttggaaatca ttcaaatact catgccaatt
    22561 taaaggaaat atcaaaagaa gacataacaa aagagataga aactacatca gaaaaaatat
    22621 ataatataac aggaaaaagg actaatttat ttagacctcc ttttggggac gtaaacaata
    22681 aagctatgga catttgtagt gatttaggtt ataaagtaat taagtgggat gtagattcta
    22741 tagactggaa ggagcttgga ccaaatcatg taattgaaaa agtaataaaa gaatctcaac
    22801 ctggttcaat agttttattc catgctaata taaatgatgt agataattat ttggatacta
    22861 taataagtcg actaaaaaaa gatggataca gtctagtcaa aatatctgat ttgttgtata
    22921 aagataatta tgtagttgat tccaatggag tgcaaaaaac taagaattaa taagtaataa
    22981 atgtatattt taagtaaagt tgtgataaat tatatagtat atgttagaaa agtgtcgata
    23041 aaaagacggt gtctattttt tgacactttt tatacatgta tgcaatatca ataattatag
    23101 attaaattga ttaaaaaagt gtctaataat tgactttttt ttgatgggtt taaaaattta
    23161 gaagaattaa tgaatgctgt aagacagtat ttccaaaggg tataagtttg tttaaaagtt
    23221 ggcatagaaa ttgctttgtt aataagcgat atgttctata gaaataaaca atatgttaag
    23281 accttataat agaaaaatag cattaacatt atttgaacag cttataaaaa aattaatata
    23341 cttaaggggg cgtactagtt gaacaaacta tattctattt tattaaaaca acacgttggt
    23401 ggtccagata agccagtagt aagtgttgga gatgtagtaa aaaaaggaac tctaatcgca
    23461 gaaccaactg gattaggggc aaatatttat gccagtgtta gtggaaaaat aagtgaaata
    23521 aatgaccaag cgatagtaat tgaagctgat gaagtacaag aagatacttt tgaaccatta
    23581 aaaggagaag gtatacttga cttaattaaa gaagctggag tagtaggaat gggtggagca
    23641 ggattcccta ctcatgtaaa attaaacata gatttaaatg gtggaacaat attagcaaat
    23701 gcagctgaat gtgaaccttt attagctcat aatataaaag aaatagaaga aagaccagaa
    23761 atagtttatc aaggtataaa atatgctatg gaagttacta atgctggaaa aggtatgcta
    23821 gcaataaaaa gtaagcatcc aaaagcaata gaagctttca aaaaagtaat aaagccagga
    23881 gacaacatag aagttgcaga actagttgat atgtacccaa tgggagaaga gagagcaata
    23941 gtaagagatg ttctaggaaa attacttgag ccaactcaat taccttcaga ggctaatgca
    24001 gtagtaataa acgtagaaac actaactaga atagtagagg ctgttgagca aaaaagacca
    24061 gttatatcta aaaatataac tgtagttggt caattaaaca gtggaaaaga atctatagtg
    24121 tttgaagatg tgccaattgg aacaactgtc ggagaattaa ttgaaagagc tggtggaata
    24181 aaaggtgaat atggtgaaat aatcctagga ggacctttca ctggtaaagc tactacttta
    24241 gatgctccaa taactaaaac tagtggtggt ataatagtta ctatgccatt tgttaatgaa
    24301 aagagaaaaa tgggtctttt agtttgtgca tgtggaccta atgaagaaag aatgagagat
    24361 atagcaacta aaatgggagt tactgatata gtatcagttc aaaaatgtaa acaagctcaa
    24421 gaaattaaag gtgcattaaa atgtgaaaat ccaggacact gtccaggaca agctcaaaaa
    24481 tgtattgaat ttaagaaagc tggagcagaa gttatattaa taggaaactg tactgactgt
    24541 agtaacacag taatgggttc tgcaccaaaa ttaaaattag gtgtatatca tattactgac
    24601 catgtaatga gaacagttaa tcacccatta ataagaagaa taaaaggtga cgtaagatta
    24661 aaaataaaat aatagataaa tagaagttag acatctttag aagtaaaact taaaagttac
    24721 ttctaaggat gttttttaat gtattttgag ggcaatatat atattgtaaa ataaatggaa
    24781 aaaatagaca aaatatgcta gatattgtat aatgataaca atagctatta caattaatat
    24841 tggacaaaaa taatgatact caagtatgtg gtttgtatta atatgcatat tatattaagt
    24901 caactatccg atagagtaaa aggtttttgt gatatttgaa gatactctat agtatctttt
    24961 ttattataaa aactaatttt tgtcttttat tagataagta tctaggatac taatttatat
    25021 tttattgagt tgttaaaaaa gtgcacttaa aaagttaaaa aagaaaaatt aaaaacctat
    25081 ttatagaaac tgtgaagtat atcttaaacc tgggcactta aaagatatat ggagttagta
    25141 gtgcaacctg ctataaatat aaataggagt aacttttaat tgtcaaaaat atataaaata
    25201 aatacataaa taagtaatta atagaagata gatataaata tatttttgaa atgctccctg
    25261 cattcataac gagtgtagag tggcagatat ctgcccaaaa ctcctttaat tgctggaagt
    25321 tcctaaagct aactaaacca caacataatc atgaaataag gataagtgtg atagagtgtg
    25381 catttaataa gcacttgagg ttacgaaagt agaaaaaatt agttagatag cataaggtta
    25441 aatcctaagt gccttgaaaa tggataatca gcaggtaagc ttcgaaaaga agaaacttca
    25501 acgactagag agaaatctcg tacctacaag tgtggggaaa tggggagtac ctaatttatg
    25561 gttaggtaat gatatagtct gtgcttaata gaaatattaa gaagttcata ggagaactgg
    25621 ttaggagtaa cgaccctaat tgaacacact aaagatgtat tattgaataa gattcatata
    25681 atatttaata attttaatta tattaagtga atacaatata tgtttttagt atcaggagaa
    25741 ttttgaaaac aaaaattaaa aaatcaagta taatcagttt agtaattgct tttagtatgg
    25801 tatttactgc atttacacca atagtatctt atgctgacga agtgactagc aatgatacaa
    25861 tacttaatgg agaagaacaa tcaaatggtc agacatcaga tgtagagaaa ccatcagacg
    25921 gtcaggtacc agatggggag aaaccatcag acagtcaagt accagatgta gagaaaccat
    25981 cagacggtca ggtaccagat ggggagaaac catcagacag tcaagtacca gatggggaga
    26041 aaccatcaga cggtcaggta ccagatgggg agaaaccatc agatggtcag ataccagatg
    26101 gggagaaacc atcagatggt cagataccag atggagagaa accatcagat ggtcagatac
    26161 cagatgggga gaaaccatca gatggtcaga tgccagatgg agagaagaca tcagatagtc
    26221 agacgccaga tgtagagaaa ccatcagatg gtcagatgcc agatggggag aaaccattag
    26281 atgagcaaac tccagaagaa gaaaaaccat tggaagaaga aatagttata gaggaaatga
    26341 gtttaaaaca agatattgat aaaattcttg atatgacttt atctcaaata aataaaatag
    26401 tatataactt ttgggaagat gaagaagatg taaaggcaga tgaacaatca gaaattaacc
    26461 aagtttttac ttcagaagac tcatttatta gcttatggta tgacaaaaaa gcaaaagtaa
    26521 aaaattcttg tttactaaaa gaaatagatg gttcagatag accttatcat gatttaagat
    26581 ttgatgatat tacaaagact ttaacttttg actatgtaat aaagggtctt gtaggagcaa
    26641 gctcaaaaga cgacaaatat gtaatagaag gtgaagatgg agagcaaact gcattttgtt
    26701 acaataatca tttaagacca ccaagtagta atggaaagag tccatattta ccagcagaag
    26761 attttaatgg tcaagaaaac caaaatgaag aagcagttaa atctatacta tatgcaggtt
    26821 ctgaatttga tggatttgga tataagcaac aatttaattt aggtggagaa gaaaatgaat
    26881 tgatgactta ctcagctact caaagtgcaa tttggattat tcttggacaa atggatgaac
    26941 aagaaagact taagcagtat caaggttcta taaacctttg tgataaactt atagaaagag
    27001 caaaaactga agaggaaaga gctgagtatc agaagaagaa agaagtagcg ataaatataa
    27061 aagcttattt agaagcattg ttaaaagcag gtcgtgaaga gttaaagcca aataatacag
    27121 gaaaacctag tttgagtaat ggtttaacta agattaactt tgaaaaaaat gaagatggta
    27181 cttatgaaac agaagctgta gccttagtag gttatagtgg tgtagtaaag ttaaaactac
    27241 cagatggagt aactgcttat gatggagatg gtaatataat aggtacaggc gaagtagaaa
    27301 tttcaacgca acagaaattt aaacttaaga gtgttggaaa accagatgcc aaagctaata
    27361 tttctgctgt atcttatgat tatatttttc caaaagctat tcaatattat aaggcagtgc
    27421 ttgatttagg acaaaaagac cattcatctt cattaccatc tagcaagcaa aatttattaa
    27481 gttatacaat agagaaaaag aatggtcaag aagttaactt taatataggt ttaccaacag
    27541 atgatgatga tgttgtaaat ccaccagtgc caccaataga tgatgatgtt gtaaatccac
    27601 cggtgccacc aacagatgat acaaatggac ataagccaaa accatcacca ccaatagatg
    27661 atacagtaat aaatccacca gtaccaccaa tggatgatac aataataaat ccaccagtac
    27721 caccaacgga ggatgcagtg ttaaatccac cagtgccacc aatggaggat gcagtgctaa
    27781 atccaccagt gccaccaaca gaggatacag tgttaaatcc accagtacca tcagtaagtg
    27841 atacagtgga aaaaactcca gaactatcaa gagatgatac aataataaaa tcaccaaaaa
    27901 caggtgatga aactcagcta atgtcatatg tatttattag tgtcattgca atttgtggat
    27961 tagcgtatca atgtaaaata aaaagaaatt aatctagatt attattaagt ttaaaataaa
    28021 aagtctcaaa ttgatttata agtcattttg gggctttttt atgtaaatat aatatgcaaa
    28081 tatagtttgt ttaaaaatat ctattttaat tatattctta aatttattat tggatacagg
    28141 cattcattaa ttgtttgatg aatagaaaaa tgttttgaag gtgaaaatag tattgaaaaa
    28201 ataatatact aagggtataa ttcatttgat ttcatttgta taaatttaat tataaatttt
    28261 aaagtgatta tataaattta aatgctaatt acttaataaa ttttaataat aattatttaa
    28321 taaataatta ttataatatg ctagaataaa tatatataaa taagttttga tgaggtacta
    28381 ctataaaggg gggactttat gttttcgata ccagaagtaa aaaaagtaga agaggtaatg
    28441 gatacaaaat ttacaactat agacgaagac acaagaattg aagatgcaat aaaagaaatg
    28501 ataaaaagca acacaaaaac tctaatggta atagattcat ctgaccaatt aaaaggcatt
    28561 atatccatga cggatataca taatctttat gagatgcata aaaagtatga aggtcaacca
    28621 gtaaaactta taatgaagaa ggatgtaata tatgtcaacg aaggtttaac cttagatgaa
    28681 tgtagagata taatgatatt aaaaaatata gggattcttc ctgttcttag agataataaa
    28741 attattggag ttctaaaaca agagcacatt agggactatc tatatatgca tttagaagat
    28801 tatggattaa ctttgaagta tattataggt caaattaaag aaggaatttg tgctataaat
    28861 aacgaaggtg ttgttatctt gtggaataag tttatggagg aaaggtatga tataaagtct
    28921 gaagatatag ttggtcgacc gatgaatgaa tttttggaaa atactatttc agaaaaagta
    28981 ctaaatagta aagttggaat gagtgacttg tattttacag ataaaaaaga aaatatgtat
    29041 gcattagttc atgcaaatcc tatattttat aaagaagaat ttatcggtgt tgtatgtaca
    29101 gaagttgatg ttacagaagc taagatatta gctcttgaac ttgaaaaagt aaatgataca
    29161 ttaaaatatc taaagaacga agtcaaaaat ttatctaaag gtagttttga taagatttta
    29221 ggtaaaagtt ataaattgga aaaatcgaaa gcgattgcaa aacaagtggc tagaacaaat
    29281 agtagtatat ttatttgggg cgaaagtggt acaggtaaag aagtatttgc aagagctatt
    29341 catgattata gtgagagaaa agggcaattt atacctgtta actgtagtgc cataccaaat
    29401 gagttatttg aaagtgagtt ttttgggtat gaatcaggtg catttacagg agcaagtaaa
    29461 aagggtcgaa taggtatatt tgaacttgca aaagatggaa ctgtattttt agatgaaatt
    29521 gccgatttac ctcttagtat gcaagcaaag ttgcttagag tattacagga aaaagaaata
    29581 agaagagttg gtggagatac cacaataaaa ataaatccta gaataatatc agctaccaat
    29641 aaagatttga gtaaaatggt aaaggcagaa aaatttagag aagatttata ctatagatta
    29701 aatgttgttg aaataaagat tcctccactt agagagagaa aagaagacat aggattattg
    29761 gttcatagct ttttagagga gatatgtaaa caaaataata agcctgttct tacaattagc
    29821 aaagatgtaa tagatatatt tcagaattat agatggaaag gtaatattag agaattaaaa
    29881 aatacgattg aaaatattgt tgtattgtca caaaattcta aaatagatgt ggatgatgta
    29941 ccaagttata tgatggattc tacaaataat agtactgaag aagaagagta tcctttagat
    30001 ttaacgaagg caactcaaaa aattgaaata aagaatataa ccaaggcact taaaatgtct
    30061 aatggaaata aagctaaagc agctaagata ttaaatatac ccagaacaac tttgtattat
    30121 aagatagacc aatacaaaat agatgtgtct aaaatatgac acatgactaa attttgacaa
    30181 aatgataaac tttaatttaa aacctagtaa agccaacact tgtataagtg ttgtgtatat
    30241 agatgtgtta aaaaaaatga aaaagtgttg attaattgac actttttttg tttgagaaaa
    30301 tgtttacaaa tacaaaaaat aacatatttt aaataaatat ttatataata tttggctaaa
    30361 aatagcgata gatgaagaat ctattataga aaaaatcttt ttgttaataa gttggcatag
    30421 gaattgctta taatataaag tgactttaag tgagaaaaaa ataatattaa tcataacaaa
    30481 ttatgtaggt tttaatttac ttaatttctc agttaagggg ttacctgttg aggaattgag
    30541 atttaaaata ataaataaga aaataatgta aggaggtatt ttatactatg tcaataactt
    30601 tagaaacagc tcaagcccat gcaaatgacc cagcagtttg ttgttgtaga tttgaagcgg
    30661 gaacaattat agcgccagaa aacttagaag atccagcaat atttgcagac ttagaggatt
    30721 ctggattatt aacaatacca gaaaatggat taactatagg tcaagtacta ggagctaagt
    30781 taaaagaaac tttagatgca ctttctccaa tgactacaga taacgtagaa ggatacaaag
    30841 caggagaggc taaagaagaa gtagtagaag aaacagtaga agaagcagct ccagtatcag
    30901 aagcagcagt agttccagta agcacaggag ttgcaggtga aacagttaaa atacacatag
    30961 gtgaaggtaa gaacataagc ttagagatac ctttatcagt agctggtcaa gcaggagttg
    31021 ctgctccagt agcaaacgtt gctgctccag tggcaagtgc agcagcagaa gtagctccaa
    31081 aagttgaaga aaagaaactt ttaagaagct taactaaaaa acactttaaa atagataaag
    31141 ttgaatttgc tgatgaaact aaaatagaag gaactacttt atacatcaga aacgcagaag
    31201 aaatatgtaa agaagctaat gaaactcaag agttagttgt agatatgaag ttagaaataa
    31261 taactcctga taaatatgaa acttacagtg aagctgtatt agatatacaa ccaatcgcta
    31321 ctaaagaaga aggcgaatta ggttcaggta taactagagt tatagatgga gctgtaatgg
    31381 tattaactgg tacagatgaa gatggagttc aaataggtga atttggttct tcagaaggtg
    31441 agttaaatac tactataatg tggggtagac caggtgctgc tgacaaaggt gaaatattca
    31501 tcaaaggtca agtaacaata aaagcaggaa ctaacatgga aagaccagga cctttagctg
    31561 ctcaccgtgc atttgactat gtaactcaag aaataagaga agcattaaag aaagttgaca
    31621 actctttagt agttgatgaa gaagtaatag agcaatacag aagagaaggt aaaaagaaag
    31681 ttgttgttat aaaagaaata atgggacaag gtgcaatgca tgataaccta atattaccag
    31741 ttgagccagt tggtacatta ggagctcaac caaacgttga cttaggaaac atgccagttg
    31801 tattatctcc acttgaagta ttagatggtg gtatccatgc attaacttgt ataggacctg
    31861 catcaaaaga aatgtcaaga cattactgga gagagccatt agtaataaga gctatggaag
    31921 acgaagaaat agatttagta ggtgttgtat ttgttggttc tccacaagta aatgctgaga
    31981 aattctatgt atctaagaga ttaggtatgt tagttgaagc tatggaagtt gatggagctg
    32041 tagtaactac tgaaggtttc ggaaacaacc atatagattt cgcatctcac atagagcaaa
    32101 taggtatgag aggtatacca gtagttggtg taagtttctc agctgttcaa ggtgctctag
    32161 ttgttggtaa taaatacatg actcacatgg tagacaacaa taagtctaag caaggtatag
    32221 agaatgaaat attatctaac aacactttag ctccagaaga tgctgttaga ataatggcta
    32281 tgcttaaaaa tgctatagaa ggtgtagaag ttaaagctcc tgaaagaaaa tggaatccaa
    32341 atgttaaatt aaataacata gaagctatag aaaaagttac aggagaaaaa atagtattag
    32401 aagagaatga gcaatctcta ccaatgagta agaagagaag agaaatatac gaaaaagacg
    32461 aaaactaaaa tttagatact aactaagatt tagacaataa cataaattta gatccaagtt
    32521 taaaacagta tagagaggta gaattataat ggataggtta aaatatatct catcagagac
    32581 tttttatgaa ggtattatag ttgacatcaa aggcggtgga gtgactatag acctaaaagg
    32641 tagacttgga caatttaaaa tacctaatag aatgcttata actgactacg aacttaagat
    32701 aggtcaagaa gttggattca tgctaagcta tcctgaggta ttaagtccag agcctaatca
    32761 agagtatgta gaaaatatta ggagagaaaa agaaaaacaa gcagaaatgc aatcaaaaca
    32821 agaagaaaaa taataaataa tcgtttgaaa atagaaggga gaggaaatat atgagcctta
    32881 caacagtaca aggacttcaa tctgaaatat tcgttccaat aacacctcct ccagtttgga
    32941 ctcctgtaac taaagaatta aaagatatga ctatagcttt agctacagca gctggtgttc
    33001 atttaaaatc tgacaagaga tttaatctag caggagatac tacatttaga gctataccta
    33061 atacagctac agttgatgaa atgatggtat cacatggtgg atatgacaat ggagatgtaa
    33121 acaaagatat aaactgtatg ttccctatag atagattaca tgaattagct gcagaaggat
    33181 ttatcaaagg agtagctcct atgcactatg cattcatggg tggtggagga aaccaacatg
    33241 tcttcactga agaaactggt cctgctatcg ctgctaaact taaggaagag ggagtagacg
    33301 gtgtagttat gacagctggc tgaggtactt gccatagaac tgccgtgatc gtgcagagag
    33361 caatagagga agctggaata cctacaataa taatagcagc tcttcctcca gtagttagac
    33421 aaaacggaac tcctagagca gttgctccat tagttccaat gggtgctaat gctggtgaac
    33481 cacataatat agaaatgcaa acacatatat taagagatac attagagcaa ttagttgcaa
    33541 taccatctgc tggtaagata gttccattac catacgaata taaagctcac gtttaaaatg
    33601 taatttatat ttgaaaatat agaacccttc tcctacacgg ttaggagagg ggttttaaga
    33661 acaaaggtgg atattatgga agaaaaaata atgagaagac ttgttataaa accgtttcat
    33721 atgaatgaag ttaatttcgg ttcaaaaact tctataaaga aagatgtact tacaatagat
    33781 ttatcaagta tagatgaaat aaaagaaaga gaagagttaa taacagacat aaaagtagac
    33841 attataaaac ctggagatta tgacagagaa attaatacta ttatggacat tataccaata
    33901 tcaacaaaag ttttaggcag actgggagag ggtattacac atactttaac gggtgtatat
    33961 gtaatgttaa ctggtgcaga tgaagatgga aatcaaatgc atgaatttgg ttcttcagaa
    34021 ggaattttga aagaccaaat ggtatttggg agatatggaa ctccatcagt tgaagattat
    34081 ataatccatg tagatgtaac tttaaaggga ggtttacctt ttgaaagaac acttccactt
    34141 gcagcattca gagcatgtga tgattttata caagaaataa gagcgtcttt gaaaatggaa
    34201 gacggaagaa atgctactca agttcgtgaa tattttgaca aaattcgacc aaatgcaaaa
    34261 aaggttgtca tagtaaaaca aatagcaggt caaggtgcta tgtatgacaa tcagttattc
    34321 tcaaaggaac ctagtggatt tgaaggagga acatcaatta tagatatggg aaatgtacct
    34381 atgattatat ctcctaatga atacagagat ggtgccctta gagctatgac ttaagagagg
    34441 tggatattat gggaatagga ccttcaacaa aagaaacatc tcttcatcac tttagagacc
    34501 cacttttaga catagttgaa agtgataagg atgtagattt acttggagta atagtagtag
    34561 gaactccaga tggaaatgaa aataaaacct ttgtgggaca aagaacggcc gcttggctgg
    34621 aagccatgag agtagatgga gctatagttt catcagatgg ttggggaaac tcacatgttg
    34681 actacgctaa cacatttgag gaaataggaa aaagagatat acctgtagtt ggagttacat
    34741 ttaatgggac tcaagctaag tttgttgtaa gcaatcaata tatggatacc atagttgata
    34801 tgaacaaatc aaaagaaggt attgagacag aagtagttgg agaaaacaac acaaatgaaa
    34861 tagatgctaa aaaagctttg gcatttttaa aacttaaaat gagaaaacat ggataaaaaa
    34921 tttaagtaag ggaatgagtt ttgtgggaat ttctacatca atgaaaaaca catcacttca
    34981 tatatttaga gacccgttac tagatttgat agataatgat tctgacatag acttgttagg
    35041 agtggttgta gttgggacat cagagcacaa tgaatggaaa acatttttag caactagact
    35101 tggaagatgg attgaatcat tgcgacctga tggagtgatt ataactttag atatggcagg
    35161 aaaccagcac attgatttta caaatgctat agcagagttt gtaaaatcag atatacctac
    35221 agtaggtctt actattatgg gagcagatgg attagtaatt accaatccat agttggataa
    35281 agctaccata attgattata aaaagacaac aggctacata gaaacagaag tagttggaga
    35341 caatcacatg gatgaagttg atgttaaaaa agcattggct ttcctaaaat taaaaatgcg
    35401 taaagacgca aaataaacct aagggggaat ttgatatgaa atttagcaga agtatacaag
    35461 ctatagactc tcatacagca ggtgaagcaa ctagaatagt tgtaggtgga atacctaaca
    35521 taaaaggaaa ttctatgcct gagaaaaaag aatatttaga ggaaaatcta gattatttaa
    35581 gaactgctat aatgttagag ccaagaggac ataatgatat gtttggttct gtaatgactc
    35641 aaccttgttg cccagatgct gactttggaa taatcttcat ggatggtggc ggatacctta
    35701 acatgtgtgg ccatggtaca ataggagcta tgacagcagc tatagaaaca ggtgtagttc
    35761 cagcagtaga gcctgtaact catgtagtta tggaagctcc agcaggaata ataagaggag
    35821 acgttacagt tgtagatgga aaagctaaag aagtatcatt cttaaacgta ccagctttct
    35881 tatataaaga aggtgttgaa gttgacttac caggtgttgg aactgttaaa tttgacatat
    35941 catttggtgg aagcttcttt gctataatac atgcaagtca attaggttta aaaatcgaac
    36001 ctcaaaatgc tggtaaatta actgaactag ctatgaaact tagagatata ataaatgaga
    36061 aaatagaaat acaacatcca actttagctc atataaaaac tgtagactta gttgaaatat
    36121 atgatgagcc aactcatcca gaagctactt acaaaaatgt agttatattt ggtcaaggtc
    36181 aagttgacag atctccatgt ggaactggaa caagtgctaa attagctact ttacatgcta
    36241 aaggtgaatt aaaagtagga gaaaaattcg tatatgaaag tatattagga actttattca
    36301 aaggtgaaat agttgaagaa actaaagttg cagatttcaa tgctgtagta cctaaaataa
    36361 ctggttctgc ttatataact ggatttaatc attttgtaat agatgaagaa gacccactta
    36421 aacatggatt tattcttaaa taagtaataa ataaattagg aaattaaaat agaatagtag
    36481 ccacttgtcg gttgctattc tatagctttt aggctataag attcagaata tatgaaaaaa
    36541 taaaaaaata ggaggatgga ttatggtagc aatcttaaag gcattatatg tagtattcgc
    36601 agcaatcttt gcagttgtgt ttggtaaaga cgtagctaaa gcaaacaaag aggggaaact
    36661 agaagaacaa agtactccaa aagttgctgt aacaggattt ataacagact tctttgatac
    36721 attaggaata gggtcatttg ctccaacaat agcaatgtca aaggctttaa agttaaatat
    36781 accagataaa aaaatgcctg gtacattaaa cgtagcacat actattccag ttgttacaga
    36841 agcattcata tttacatcaa tcataccagt tgatggtgtt actttagtat ctatggttgt
    36901 ggcagcagca gttggttcat atataggtgc aggaataata gctaagatgg acgagagaaa
    36961 aatacaactt gttatgggtg taactttagc attaacagca atattaatgt tattaggtca
    37021 tccttggatt aacgtattac caggtggagg aaatgaatta ggtcttactg gtgttaaatt
    37081 agtaataggt gtaataggta actttatact aggagcttta atgacagctg gtataggttt
    37141 atatgctcca ggtatggcaa tggtttattt cttaggaatg tctgcaaaag ttgcattccc
    37201 aatagttatg ggttcttgtg cattattaat gccagttgca agtatgaaat tcataaaaga
    37261 agatgcatat actaaaaaag catcagttat aatagctata tgtggtttaa taggagtttt
    37321 cgtagctgca tatatagtaa aaactctacc aatggatata ttaaaagcat tagtaatagt
    37381 agttatagct tatacttctg ctacaatgat aatggctgca aataaaaaca aaaagactgc
    37441 ttagttaaag actacttagt gtttattaaa tattacagct aataataaag attataaact
    37501 gctttaaaat attgaattaa tattttaggg cagtttttta tttactaaat taatataaag
    37561 caattaacat gccaattatg taatatatat agtgatttag tagatttaat gtaaaaaacg
    37621 ttgtattttt aaagaataaa gcataattta aagctaaata tttaaatttt ataatcaata
    37681 agttcaataa atgttcatat attaatacag attaataaaa atataaccta taataagtct
    37741 aatataactt ataattaaga aaaataagtt tataatgact caatattcat ctgaattatt
    37801 tgaataaatt taattcgttg aagttgctta tatagagtg
//
LOCUS       DAJMZY010000030        37436 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.030, whole genome shotgun sequence.
ACCESSION   DAJMZY010000030 DAJMZY010000000
VERSION     DAJMZY010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 37436)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37436)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37436
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.030"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            complement(<1..993)
                     /locus_tag="OE968_001485"
     CDS             complement(<1..993)
                     /locus_tag="OE968_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HCP7218768.1"
                     /translation="MIKSSLFWNIFIAISFMIEWFLCKKMLDYTSEKRISNKKINFCV
                     VGIIVFADIIYFFDVPPNIRVIISMIITIAFYKISYDVGFIKSVLISLIYWMLLIATD
                     ALSISLTVWLNSINDMSSMGTGDIYRIESIILGKILLIVSLLLYRALKIKLNIEINKR
                     TLFYIVIPIVANIASFFVIFEYIFNPGSGSLIHNFQFVMISVVLLISSITLVLIAKKL
                     QQYNTLVVENNMIKNTLKYENEYYEDIEKKYLKTRLLSHDMKNHILCINAMIKKGIDV
                     TSYLNNLQVEIQSNDLLFNTGNFILDAILSEKKEVCDKNDIELKIGINFSCCEAV"
     gene            complement(1663..2754)
                     /locus_tag="OE968_001486"
     CDS             complement(1663..2754)
                     /locus_tag="OE968_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HCP7218769.1"
                     /translation="MIEKVEEKSKIIKTSKEYKRTIIEEKDKEWTKKLNDILSRSSFS
                     NDELDKIKALIPKEILTNENVGEVVTEDGYAKPEYDEVFKSLFTLNNEYDLLVNFIND
                     ILKDAPYANRNIKPFTQIKRIIRVETDPTINYIGEKRPKLDILAEDEENNHINIEMQR
                     AFENDYLERAEYYLSRVHGRKLEEGKEYKEIGKTIGIHILNHVKYNHIEDYVNCLRLT
                     MDGHPDIYSSKTALYFIELPKIHKSDYIVNRIMLWGKLISNPSNLDVRVIAKNDSIIK
                     KALDRLKELGSNEEYLLNLKRGAYIMNKSRNFKEEIERETAIRVAKEKDYKIIIMLKK
                     NGFKLDDILNKFNDFDLSEDEIKEVYENN"
     gene            complement(3522..5441)
                     /gene="thrS"
                     /locus_tag="OE968_001487"
     CDS             complement(3522..5441)
                     /gene="thrS"
                     /locus_tag="OE968_001487"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HCP7218770.1"
                     /translation="MIKVALKDGSIKEFENAISVMDVAKSISEGLARNVVAASVNGEV
                     VGLDHIIDTDCDLNLFKFEDKEGKEVFRHTSAHILAQAIKRLYPEAKLAIGPSIENGF
                     YYDIDLDHRLVPEDLEKIEAEMKKIAKEDLKIERFELPRNEALELMKEQGEDYKVELI
                     SDLPESEIISFYKQGDFTDLCRGPHLPSTKKVKAVKLQSVAGAYWRGDENNKMLQRIY
                     GTSFEKNKDLEEYLHLLEEAKKRDHRKLGKELGLFMIPEEGPGFPMFLPKGMELKNEL
                     LKFWREIHRKAGYIEIESPIILNRKLWETSGHWYHYKENMYTVKIDDEDYAIKPMNCP
                     GGLIYYNSQLHSYRDFPMRVAELGRVHRHELSGALQGLMRVRAFTQDDSHIFMLPEQI
                     KDEIKGVANLIDGIYKTFGFEYNLELSTRPENSMGSDEEWEAAENGLREALEELGLPY
                     TINEGDGAFYGPKIDFHLKDCLGRTWQCGTIQLDMQLPRQFDNTYIGQDGEKHRPVMI
                     HRVAFGSIERFIGILIEHYAGKFPVWLSPTQVKILPISDKFMDYANEVKKELFDKGIR
                     VELDDRAEKIGFKIREAQLEKVPYMLIVGEKEVADNNVSVRSRDKGEIGSIKLDEFIA
                     SISKEIESRESIIQD"
     misc_binding    complement(5505..5742)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(6201..6803)
                     /locus_tag="OE968_001488"
     CDS             complement(6201..6803)
                     /locus_tag="OE968_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF445 family protein"
                     /protein_id="HCP7218771.1"
                     /translation="MDNLIRILILAVIGGFIGYVTNVVAIRLIFRPIEPIKIPILNIE
                     IVGLIPKRRAEIAANVGEIIQEEFLSMDEILANIITDEDKEEVVRYIKARVKIIIHEK
                     VSFIPSGIKNMIQDYLGEIIESEVKQSIDELSKNIINKANERIDIQKMVEDKINELDL
                     YELEEIIIRIAKKELKHIEFLGLVLGFLIGIAQGLITMFI"
     gene            complement(6983..7801)
                     /locus_tag="OE968_001489"
     CDS             complement(6983..7801)
                     /locus_tag="OE968_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sporulation protein YtxC"
                     /protein_id="HCP7218772.1"
                     /translation="MVEKDNISSMKFLRNNNVNDRLIYTNDIVEVVIDSAKQEVLNKK
                     ILNGTKAEQRALNIDEISTEITSMIISIMKEKLLKEYILKCYGRTYPEDKNNIYIYSL
                     NIFAKKEIFMRETVFTRVRNYIEENDFINVEGFIRFRMREFMKYISAIGDIAVEEYLI
                     KKDQDEFIRVLKYFIDTQEEKIDLLKVHIMEDNTFVLYDKNGNKIDSIDDEEIINMVI
                     RENLNYEDFLISTLLTLCPKKIEILDLLNNNCSKEIIDTVEAIFENKVSIIMEN"
     gene            complement(7804..8565)
                     /locus_tag="OE968_001490"
     CDS             complement(7804..8565)
                     /locus_tag="OE968_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218773.1"
                     /translation="MEFTREPFILDDDLCLALVDKRISYLMENELKLRNIEIIKTIEC
                     KELYESIKYHPDICICNLGKGDIIVAPNVYNQYKELLSRYKFNIIKGEANLLNRYPYD
                     IPYNIAIVGDYAIHNFKYTDKAILDYIENNKLKKINIEQGYSKCSICIVDRTSIITSD
                     KGIWKSMKNTEIECLLIEKGHINLFEMNYGFIGGCTGLISKDKLAFCGDVKKHPDYER
                     IKSFVESKNKEIVTLSCENLLDIGSIVPLMTRKER"
     gene            complement(9055..10167)
                     /locus_tag="OE968_001491"
     CDS             complement(9055..10167)
                     /locus_tag="OE968_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HCP7218774.1"
                     /translation="MKIKRILMACFVVVFTIFILAICNFDFGFDKVNKNNSNIDSAKS
                     KQSESKSLPTSAEKDKSNSKSKNKEDDTEDDSYVRKTIGVLLDTENLNNESYNNNVLS
                     ALKRADEDFDVRIKLEKPKTSKSFKESIEKLHKYEPDLIIAVGARFAEPIKEAATEYP
                     KQQFAIVDYTYKVQPANVISVSFQDNVTGYLAGLIAGKMTDTGKVGFIGGVEGSSRDK
                     YESGFRKGLKTSNKDAELLVKYSNIFENPESARTIAKEMRDSDRDVVFSATEDDSKRA
                     IQVARENGGKVIAINKDQYDMAPDNVISSIIKDVEQPVYELIKNVAKDGFKGSKVMEF
                     KIKDGELGLTSKSSRNIPPDVLEYIKKEYNKVKDTY"
     gene            complement(10293..11297)
                     /locus_tag="OE968_001492"
     CDS             complement(10293..11297)
                     /locus_tag="OE968_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HCP7218775.1"
                     /translation="MRFKRILILMLTVAMIAGMLVGCANNPSNNPSSSKDNKSDISDK
                     SNSKKSVSMILDIEGTNNEAMNNSALLALNNAQKKLNIDTNKVESDDSSTFSNSIDIL
                     CNDNYDLIIAVGARFAKPLEMVAKKYPKQQFAIIDYEYDKQPSNITSISYEDNKSGYL
                     AGLIAGKMTESDKVGFIGGTKSSSRDKFESGFREGVKFSNSSIKDISVEYADVFKDSK
                     SVESIAKKMMDNGVDIIFSTTEDDSKAVIDAVRAKNKKVIATNKDQHELAPENVISSI
                     VKDFENPTYNLIQSFVKGNYKGGKVIENTVKSGSTGLAQNSSQNIPPDVLEYVNKNNK
                     "
     gene            complement(11619..12467)
                     /locus_tag="OE968_001493"
     CDS             complement(11619..12467)
                     /locus_tag="OE968_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HCP7218776.1"
                     /translation="MKNLKIICDSLSDVPKDLLDKYDIDIVSLTVILEEREYKDRIDI
                     SGDEFYKKLREENVYPKTSQATYAQFKEIFEKYTNEDREILYIAGSATATGTYQSAVM
                     AKNDVDGKIYTYDSNLLCMGTGLLVIKAGELASEGKSVAEILPVLDELKEKAFVIFSV
                     DTLEYLQKGGRISSTKAAIGSILNIKPILEIRDGLVSQISQVRGKKNVISKMMELIKS
                     NCGDDLSDQIVYIGYSDDFKEKEQLSKVMQDELRPKEIRFFQIGVCIGAHAGPGVTGI
                     ICLKNK"
     gene            complement(12503..12973)
                     /gene="trmL"
                     /locus_tag="OE968_001494"
     CDS             complement(12503..12973)
                     /gene="trmL"
                     /locus_tag="OE968_001494"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HCP7218777.1"
                     /translation="MSLNIVLVEPEIPQNTGNIIRTCAATGSTLHLVKPLGFSLDDKH
                     LKRCGLDYWDIADIQYYDSFEELQEKYPNSKYFFSTTKAKQSHSDVKYEENCFIVFGK
                     ETKGLPEPLLKANMDTCIRVPMLDVEKARSLNLSNSVAIVVYEALRQIGYPNMR"
     gene            complement(13167..14384)
                     /gene="nth"
                     /locus_tag="OE968_001495"
     CDS             complement(13167..14384)
                     /gene="nth"
                     /locus_tag="OE968_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HCP7218778.1"
                     /translation="MKNVNLKEINEKDVILEEEINKKGMDKKNIIEKEEINKKGIDKK
                     DIIEKEEINKKGIDKKDIIEKKEINKKGIDKKDIIEKKEINKKEMDKKDIIEKEEINK
                     KGMNKKDIIEKEEINEKEIDKMIGKKDEIIDEKDIENFMDIEEDKKSIKVSKKSTKKG
                     ETEKKTKKSSSNKATQKTSKETKSKFKIKNESANEKDVNKILDELEKLYPDAKCELNY
                     GTAFELLIATILSAQCTDVRVNKVTSELFKKYNTARDFANLSIEEISKEIKSCGLYKS
                     KSQKIKDTSEQLCELYDGEVPDSLEKLIKLPGVGRKTAGVVLSNAFNHPAIAVDTHVF
                     RVSNRIGIVDEPNPQKTEFALMEAIPKERWSHSHHVLIFHGRRMCKARNPECASCPIK
                     EDCNYYKELNETK"
     gene            complement(14582..16819)
                     /locus_tag="OE968_001496"
     CDS             complement(14582..16819)
                     /locus_tag="OE968_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HCP7218779.1"
                     /translation="MKYNNTSEINPLDYILGQERAVEAMELGLKINNPAYNIYIAGEP
                     GTGKSTYALKVLNEYASKKNTHKDWCYIYNFENPREPIIVELEKGFGRELKKDMEKLI
                     ESLLEDFKNAFESENFEIEKNKLLDEYEIEKDMLLKQIKKYGEEKGFKLKQSKMGIVF
                     IPLKEEEDESDESDEEFYKAKRELENMAIQVVYKIRNLEEIAEKAVLELEEEIAKLVV
                     EPHIKRLCEKYENYDKIQTYLENIKKDIIEYMYLFYLDEEELKDKYDKEHFIKYKINL
                     FVDNGSSKNKESAPVVVEINPSPANLFGKAEYDYANGNIKTDFTKLLSGAFHRANGGY
                     LVLYADQLLKYTMSWEILKKTLQTKKVILETQTAIKPENMPLDVKLVLIGSHYIYDIL
                     YRYDEDFEKYFKVFVDFDSEMDKNEDNEEGIARFIAYQCDKNNLRHFTKSAVEEVIKF
                     STRLSGDLEKLSTKFNKIMEVVIEGSAYAEFRNSEYTKQCDVKKAISEKRKRINRVET
                     HMDESIENGFTLIETEGRKVGVINGLSVLSTGEYSFGRASRITATTSPGSKGIVNIER
                     EVNMSGSIHNKGVLILGGYLSENFAQDLLLSLNAYVCFEQNYGGIDGDSASSAELYVL
                     LSSLSGVSIKQNIAVTGSINQKGDIQVVGGISEKIEGFYSICKTKGLNGEQGVIIPRK
                     NQRNLVLSDEVNDAVRDGKFKIYTVERVEEAIEILTDVKFEEIKKLVKEKLISFSKIQ
                     TVSKE"
     gene            complement(16925..17839)
                     /gene="queG"
                     /locus_tag="OE968_001497"
     CDS             complement(16925..17839)
                     /gene="queG"
                     /locus_tag="OE968_001497"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HCP7218780.1"
                     /translation="MDNKELKAFCNLIGLNCVGVAGVDKYDNLEKILKNRQQKGYLTG
                     MEEPIIESRINPRHIMKDANSIIVCAFPYHINRQEKNKNSNLSKYCHGKDYHIVVKDF
                     LQQICDYISKTVTDFKYKLFADNGPLVDRYLAYLSGIGYFGINNNIITDEYGSYVFIG
                     YIVNNYKFEEDKPLEKSCFKCGKCVKYCPGNAILGNYDMNPKKCLSYITQKKGDLSEK
                     EKVVLKNGKKVFGCDICQEVCPHNVEIPTTHILEFKENIIDYLDYDEIQNISNKEFKR
                     RYGDRAFSWRGRNIIKRNMEIILDKYDD"
     gene            18680..19084
                     /locus_tag="OE968_001498"
     CDS             18680..19084
                     /locus_tag="OE968_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HCP7218781.1"
                     /translation="MIKITIPGRPISKSNFKLHNINGQAWMPSKGKYSKYLAYENMIA
                     GFINQQYQGETVEENLITVLKLFFPNKRMGDLHNYPKSICDGIEKSGIIKNDKQLKPV
                     LLFDFIDKDNPRVEIELYPVSKYDISYNIFEK"
     gene            complement(19341..20336)
                     /locus_tag="OE968_001499"
     CDS             complement(19341..20336)
                     /locus_tag="OE968_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HCP7218782.1"
                     /translation="MRNLGNTNMKIKRVGFGGIPIQRITQDDTNLVINELEKQGINFI
                     DSARGYTISEEAIGIAIEGKRDKFFLATKSMSRDYDSMKRDVEISLNNFKTDFIDLYQ
                     FHNVKEEEYDNLFKDKMAYSALLEAKEQGKIKHIGITSHNLNTIEKAIEDGKFDTIQF
                     PYNIVEGQADEVFKKAHEKGIGIIVMKPLAGGALDNATLAIKYILSKDYIDVVIPGME
                     SVEQVRQNVAVLENLVLDEKDNKEIEEIRNSLGKKFCRRCEYCMPCAVGINIPLSFLC
                     EGYYTRYGLKEWAKEKYEVMDVKPTECIDCGLCESRCPYELPIREMLKTVVEKLG"
     gene            complement(20620..21456)
                     /locus_tag="OE968_001500"
     CDS             complement(20620..21456)
                     /locus_tag="OE968_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HCP7218783.1"
                     /translation="MIKLGTHLSIAKGFANAAETAVYIGANTFQFFSRNPRGGNAKEF
                     DEKDIIKFQEIRKENNFAPLLAHAPYTMNLGGTKDDVYEFATRVIDEDIRRMDSLGIE
                     YMCFHPGSHVGGGVDFGIDRIVKGLNNAIKGDENITILLETMSGKGTEIGFKFEQLKS
                     IIDKIEHKEKIGVCLDTCHIFSAGYDIVNDLDGVLEEFDKVIGIERLKTVHLNDSMMP
                     FGDKKDRHAPIGEGKIGLKALIDFMEHPSLKHLPFFLETPFDDEGHKKELKMIKEILS
                     SK"
     gene            complement(21944..22507)
                     /locus_tag="OE968_001501"
     CDS             complement(21944..22507)
                     /locus_tag="OE968_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCP7218784.1"
                     /translation="MKEVLVLRDLECIKAIAHPRRIDILKAFDKSPLSAKQLSQLLEE
                     PHAKINYHIKMLYKVGILELVEEKIKSGIVEKYYYPSAKNVVIGNRILNFSLDNGEEK
                     EELYISKFENMSEVFYKAAEEDVLENENIVDYHDISLTHDELVELSDTMKSKIDEILN
                     KRQHNVEGSKYDIAMVIVPTLEEECPS"
     gene            complement(22605..23534)
                     /gene="glsA"
                     /locus_tag="OE968_001502"
     CDS             complement(22605..23534)
                     /gene="glsA"
                     /locus_tag="OE968_001502"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HCP7218785.1"
                     /translation="MNTLDETLLKEIISSNKKYTNYGQVASYIPELKNARRNDLGICI
                     IDSENNLYSAGNCSTKFTIQSISKPIVLAMALMDNDWEDVFSNVGMEPSGDPFNSIMK
                     LEINDTKKPCNPMINAGAIVTTSLINGSCLEEKEERMLSFFRKLAKNDNIGINYDVYK
                     SEKMTGDRNRAMAYLLKSDGFIRGNVEDVLDLYFKQCSIEIDSVDLARIGINLANYGV
                     DIENGEHLMSEMVSRIVKTFMMTCGMYDASGEFAIKVGIPAKSGVGGGIMASVPGRMG
                     IGVYGPALDKKGNSVAGVKVLEELSNKLKLNIF"
     gene            complement(24067..25734)
                     /locus_tag="OE968_001503"
     CDS             complement(24067..25734)
                     /locus_tag="OE968_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside kinase"
                     /protein_id="HCP7218786.1"
                     /translation="MKKINLKIEGKDKEYSLEENSPGIRLGDIAKEFCDEHKGYITLA
                     VVDNKLKELNCRVKKDCEINFLDTTNEDGERVYFRVMSFIFVMACREIFWDSRVTIEH
                     SLSDGLYCEVHIDRKLKEADVENIKNKMKEIVNNDYVIEKIEVTRNEAISIFENNEMY
                     EKAELLKYKEYDSAKVYKCRNYIDHFYGYMLPSTGYIKSFDIKLYNGGVIILGPSEED
                     KTLPMKFVPQPKLSSVYYEAEEWSRLMGIDKVVSLNKIIENNEYGDIIRTFEALHEKK
                     LSQIADMIKDGNKRVVLIAAPSSSGKTSFAHRLSIHLRVNNLNPISISLDDYFIDRKH
                     TPLDEYGNYDFESIYAIDLEKFNLDLKKLLAGEEIDDIRFNFKEGKREYTGKKIKIDS
                     NQPIILEGIHGLNPILTSSIPDEDKFKIYISALTQINLDDHNRIPTADLRMIRRIVRD
                     YNFRGYSADNTILQWASVRRGEKKNIFPYQEEADAIFNSACVYELAVLKRFAKPLLEE
                     IKEDNPAHIEATRLLKFLQYFVELDDTSDIPGISILREFIGGSKIVD"
     gene            complement(25808..26563)
                     /locus_tag="OE968_001504"
     CDS             complement(25808..26563)
                     /locus_tag="OE968_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM barrel protein"
                     /protein_id="HCP7218787.1"
                     /translation="MAVGIASLLFNIEEALNICESIKQITHLEIGIDNISECSELCKY
                     KERISKLGLSIGIHLPMELNTCENIEYIRNSWINFIEKIEFELKGFDLRYFNLHLGYV
                     MTNRVRKNRDKYLGNSVDFLDKLNTNSYVCIENTYSKGGDFSNIGNISYDFEYIFKRI
                     KNSKICFCYDTGHCLIDEDAYVKNLKDKIRLIHLSDNDGINDTHVGIGRGILSEEGIK
                     EVLTLDAEYLVLEINYEDIEDTISKLNNIVGEG"
     gene            complement(26573..27109)
                     /gene="lepB"
                     /locus_tag="OE968_001505"
     CDS             complement(26573..27109)
                     /gene="lepB"
                     /locus_tag="OE968_001505"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HCP7218788.1"
                     /translation="MNETIKEEIVEWIKIIITALFFAFIITRFIKPTLVNGESMYPTL
                     KSHDYLVANRMTYKLSEPKCGDIMIFKTDLLQENGRKKELVKRVIGVPGDHLKIKDSK
                     VYINGKLLNEVSYIHDNYTEGDIDMVIPKGKVFAMGDNREVSLDSRYKEVGLVDEENI
                     KGKVILRVFPFTDIGIFE"
     gene            complement(27275..27811)
                     /gene="lepB"
                     /locus_tag="OE968_001506"
     CDS             complement(27275..27811)
                     /gene="lepB"
                     /locus_tag="OE968_001506"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HCP7218789.1"
                     /translation="MGEAVKKEVVEWIKVIVIALVLAFAITRFIVPTIVKGESMYPTL
                     VERDYLIVNRIAYKVGEPKYKDIIVFKTDLTEENGKKKDLVKRVIGVPGDHVKIQDSK
                     VYVNDKLLDETSYIHNNRTDGDIDIVVPEGKLFAMGDNREKSLDSRYDEVGLVDEHTI
                     LGKVLVRLYPFSKIGTID"
     gene            complement(27911..29221)
                     /locus_tag="OE968_001507"
     CDS             complement(27911..29221)
                     /locus_tag="OE968_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmB/NOP family class I SAM-dependent RNA
                     methyltransferase"
                     /protein_id="HCP7218790.1"
                     /translation="MTELPNEFLEDIEEILKDEYDDFIKSYEESKTTGLRINTLKIDK
                     KKLFDLELFDLNQIPWAEEGFYYDDKIDRPGRNPLHEAGAYYLQEPSAMSVIPKADIK
                     EGEKVLDMCAAPGGKSTYILSKLNDTGLLVSNEINASRIKALGENLERFGARNCIITN
                     TDSNSLRKTFNGYFDKVIIDAPCSGQGMFRKDEVAISDWSYAKVVECQSIQKEIIRDG
                     YKMLKKDGILIYSTCTFSREENEHVINEFISEYPHAELIEMERLWPHKIKGEGHFVAK
                     IKKLEEEECNVKELKIKNLDKEIKDYREFEKKFLKVDFYSNKKNKFYLRGENLYLLPE
                     IYPDTKKLKVLRYGLHLGVLKKNRFEPSHALSHYLKVEDVKNVENFSVQSESILKYLK
                     GDVVNSNDSRGWVLVSVEGIPLGWGKESSGVIKNHYPKGLRKVF"
     gene            complement(29300..30016)
                     /locus_tag="OE968_001508"
     CDS             complement(29300..30016)
                     /locus_tag="OE968_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HCP7218791.1"
                     /translation="MKLDLFLLAIVPILIGMFWIRSKDRYCREPLIHLIKFFLIGAFL
                     SVIIILLENLLMKFNVFEGYSELIYVSFVVAGLVEEGVKALILIPALIKEKHFTEKLD
                     GIIYSVFLALGFATIENMVYIFSESRNLALQVGINRAVISIPAHVMFAITMGYYISKY
                     KFEGNKNKRREYLFMAVLIPILLHGVFDFILMIEYRWAIILLIVYVIILWKINLDKLE
                     KYMNHSKKVFFGNLRKKKKK"
     gene            30261..31532
                     /gene="sleC"
                     /locus_tag="OE968_001509"
     CDS             30261..31532
                     /gene="sleC"
                     /locus_tag="OE968_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore cortex-lytic protein SleC"
                     /protein_id="HCP7218792.1"
                     /translation="MQDGFLTVSIIDATNNRPIQNAVVNIYSMSNGSQSSSTLYQNLR
                     SNESGQVTGLVLPAPDVDYSLQPSDVRPYSQYIVEAIADGYETVVIEGTQLLATIEAR
                     QGVPMSPRTRSKRSFSRQSELIFDIGEHTLYGTYPPKIPESNLKPLPPPTGFVVLDNP
                     VVPEFIVVHDGLPEDSSAPNYWIPFKEYIKNIASSEIYSTWPEQTIYANVIAIISFTL
                     NRVFTEWYRNKGYNFTITSTTAYDHKFINNRNLFEPINVVVDAIFNTFIKRPPTSRQP
                     LLAQYCDGQKSQCPDQMTQWGSKDLGDQGYDYESILRYFYGDEIVFERAPIVSGVPVS
                     FPGTTLQVGSSGQYVRTIQNQLNAISNSYPAVPKVIEDGIYGTDTENAVKIFQGIFGL
                     PQSGVVDFKTWYEISRVYVATTRIASLNPLI"
     gene            complement(32040..32696)
                     /locus_tag="OE968_001510"
     CDS             complement(32040..32696)
                     /locus_tag="OE968_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218793.1"
                     /translation="MKKGDFIWSGVLICIIAVLAIPSSREVFMEATGAHPYIGGFLKF
                     AVLATMGDLLGARILYKDWKIPVGVFYRAIVWGIIGVVTTYGMSIYSSGVGQAQVDGM
                     LPFEGIAFANALFKSATMNILMSPTVFLFHKVMDCFIDKKYEVGKGIKVKLKDVVNIV
                     DWNAYLGFSVLKTIPFFWIPCHTIVFLFPAEYRVIASAFASIALGLILALANKSKVAV
                     "
     gene            complement(33968..34378)
                     /locus_tag="OE968_001511"
     CDS             complement(33968..34378)
                     /locus_tag="OE968_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218794.1"
                     /translation="MKIKKSLISAMMVSAMVLGGTGAVFANGNDSSNIALPKLESLIK
                     SGITDPTELEKYGVEHYTYEEYAKHIQELKDYAKDPNAVKDVSQKDLEETIKKMEQEL
                     EKIKTEGLKIMKPITIENEDGSQISIAYNYAAID"
     gene            complement(34594..35976)
                     /locus_tag="OE968_001512"
     CDS             complement(34594..35976)
                     /locus_tag="OE968_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M56 family metallopeptidase"
                     /protein_id="HCP7218795.1"
                     /translation="MFIKLLEMSFTSGVLLLIVIFIRACLFKKLPKKVFVLLWLIVLF
                     KLLIPVSLNSGFSIYSIIESTFDVELGNTSTENYTLKKASDSTGKNNSDEFEIMSNIE
                     NIMMLEMLGILSFIVTIMFSILLCFRYFKIINLFKTSIHIKNHEFIKKWMCKNSRFRR
                     FIVCISEFTRTPLTSGILKPRIILPKQMNYANNQTLDFVLTHEMVHINSFDNLLKLFM
                     LVALVVHWFNPLVWVMFFLLNKDIEFSCDEKVMSILGEEYRADYATTLISLAEENNPF
                     SMTICSGFGKTKIEKRIVNIMKFKKSTYVTFLVSTVLVCGTGLVFATENKEINEVESF
                     GLTKNEQSDKIGFSISSKSTDLYSPKVESDILVSKAKSDGETHFSTAKVSVIEFREHE
                     ESSMSKVTNSENSEETYVNKSSNGKDVLYTDSGEVSIEQSGYNDNRFVISRKGNLLAV
                     NKEQYRTWIE"
     gene            complement(35987..36346)
                     /locus_tag="OE968_001513"
     CDS             complement(35987..36346)
                     /locus_tag="OE968_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HCP7218796.1"
                     /translation="MEIKLFDSELKVMEVLWERGESKAGELVKILKEETGWNRNTTYT
                     VIKKLVSKGAIERIEPNFVCKALISKEEVQKQETETLINKMFGGSSEKFLSAFINKEN
                     LSSDEITKLKQIVEKLK"
     gene            complement(36551..37330)
                     /locus_tag="OE968_001514"
     CDS             complement(36551..37330)
                     /locus_tag="OE968_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HCP7218797.1"
                     /translation="MVSRQELKRVSKAQLSGNWGICAISMAVYIALIVLISIVGLPFE
                     PLTTIVVAVIAFCVSAGFTCMFLKITKDEKVKIGDIFVSGRIYLRSFGFYLFESIIVY
                     IYSFIITIIGAFLSFGVLLTSGAIEYLSSDNVGIGTVISTGITLVLIILVLMLPVYIL
                     LLYVSQATFLICEDKDNMGVFKSMGASLDMMKGNVLKLFVLNFSFIGWYILSIATLGI
                     GLLWLIPYVGVTNCNFYRQLVKENPDVEDILLDKEKSYTMY"
BASE COUNT        12210 a         6790 c         3516 g        14920 t
ORIGIN      
        1 aacagcttca caacaactaa aatttattcc tatttttagt tctatatcat tcttatcaca
       61 aacctctttc ttttcactta atatagcatc taatataaaa ttaccagtat taaataacaa
      121 gtcattactc tgaatttcta cctgcaaatt atttaaataa gaagtaacat caataccttt
      181 tttaatcata gcatttatac acaagatgtg atttttcata tcatgactta gtaatctagt
      241 ttttaaatat ttcttttcta tatcttcata atactcattt tcatacttca aagtattttt
      301 aatcatatta ttttctacaa ctaaagtatt atattgctgt aattttttag caattaaaac
      361 taaagtgata cttgatataa gcaatacaac agaaatcata acgaattgga aattatgtat
      421 taagctacca gaccctggat taaatatgta ttcaaaaatt acaaaaaaag atgctatatt
      481 agcgactata ggaataacta tataaaataa tgtcctttta tttatttcta tattaagttt
      541 tatctttaag gctctatata aaagcaaaga cacaatcaaa agtatctttc ccaatattat
      601 agactcaatt ctgtatatat ctcccgtccc catactactc atgtcattta tagaattaag
      661 ccaaactgtt aaagatatac tcaaagcatc tgtggcgatt agtaacatcc aataaattaa
      721 ggatattaat acagacttta taaaccccac atcatatgag attttataaa atgcaatagt
      781 aattatcata gatataatta ctcttatatt tggaggtaca tcaaaaaaat atattatgtc
      841 agcaaaaaca ataataccta ccacacaaaa gtttattttt ttgttagaaa tccttttctc
      901 acttgtataa tctagcattt tcttacaaag aaaccattct atcataaagg atatcgcaat
      961 gaaaatattc caaaataagc ttgactttat cataatactt tctcctaacg tattactaaa
     1021 ttattttttt atattttatg tataatttaa ttatatacga ctctacacgt gtagtaaata
     1081 gattgtcaaa attattccaa ataagtccat atttcttttc ttttttaatt atatcactaa
     1141 atttgctaaa ttgaattaaa ctttttattg ctttttttaa taataactat ataaatttat
     1201 ctataactag gtataaaata tattatttat aaagttttta cattatttcc ataataaaat
     1261 cttataaata ttacaataaa atattttttt ccatgatata ccttgataaa atctctgctt
     1321 ctttaagcag taactttgag ttgaatcatt atagtgattt ataacattta tagaaatgct
     1381 gttatagatt tatatttaaa cactacaaat ggaaatttaa ctattataaa aaacaatcat
     1441 tagataaaat gattcttaca acaaaagcat ttctattgta gatttattag taaataataa
     1501 atctacaata gaaaaaacta gaagtacagt atcataaaaa tataattaac tgtacttcta
     1561 aattattgtt tttaaaataa attttcattc attaaaaaat acacataaat atttccagac
     1621 tccgattcag caaacttata taagttcact ttttatttat catcaattat tttcatatac
     1681 ttcttttatc tcatcttcac ttaagtcaaa atcattaaat ttatttaata tgtcatctaa
     1741 tttaaaacca ttttttttca acattataat tattttataa tctttttctt ttgcaactct
     1801 aattgctgtc tctctttcaa tctcttcttt aaaatttcta cttttattca tgatataagc
     1861 acctcttttc agatttaata aatattcttc attgctacct aattctttta atctatcaag
     1921 tgctttttta ataatagaat cattcttagc tataactctt acatctaagt tagaaggatt
     1981 actaataagt tttccccata gcataattct atttactata tagtcagatt tatgaatttt
     2041 tggaagctct ataaaatata atgcagtttt actagaataa atatctggat gcccgtccat
     2101 tgttaatctc aggcaattta cataatcttc tatgtgatta tattttacat gatttagtat
     2161 atgtattcca atagtttttc caatttcttt atactcttta ccttcttcta actttctacc
     2221 atgtacacga ctaagataat attcagctct ttccaaataa tcgttctcaa aagctctttg
     2281 catctcaata tttatatgat tattttcttc atcttcagcc aaaatatcaa gtttaggtct
     2341 tttctctcca atgtaattaa ttgttggatc agtttcaact ctaattattc tctttatttg
     2401 agtgaacggt ttgatattcc tgttagcata tggagcatct tttagaatat catttataaa
     2461 atttacaagt aaatcatatt cattatttaa agtgaacaat gatttaaata cctcatcata
     2521 ctcgggctta gcatatccat cttcagtcac aacttctcca acattttcat tagtcaaaat
     2581 ctcttttgga attaacgcct tgattttatc taattcatca ttagaaaaac tacttctact
     2641 aagtatatca tttaattttt tggtccattc tttatctttt tcttcaatta tagttcgctt
     2701 atattctttt gatgttttaa taatcttaga tttttcttct actttttcta tcatttcaac
     2761 acctctcttt ttcctctttt gtatttatca tttcttgaaa ttaaactaag tcactacctc
     2821 ttttaaaagt tcttgctcca taaacacttt cttaaactct aatgtctgtg tatgtacttg
     2881 acattctctc tctatctaaa gttaaataaa ttaatctatg tatagagggt aagtccaaaa
     2941 ataacataaa acactaatta atcatttata aagcattaat taatcactga caatgctgtt
     3001 attgtcacca catagcacca acatagattc ttctattata gggcaattat ctatgaaaaa
     3061 tagactcata agattagaaa atgtacttaa attttagttc atttaaatat tcattttgaa
     3121 gaaagaaatt taactttaga ctaaaaagga aatatttcaa gaggattaag aaattttctt
     3181 aaagggataa taatttttat gaaaatggaa caaatatgaa aataaagtta tgatttttac
     3241 agccataacc ttaccaacaa gcacttaatt atcactcaaa aaataaacgt ttatttaaag
     3301 aatgcacata aatatttcca tgttcaaaac acttctatga tatatttatt aataaatcta
     3361 ccatacaaaa aactagaggt acattaatca taaaaatatg attaactgta cctctaatta
     3421 tactcatctt ttcataaatt taatcactat gcatcaacat atcaacatat tgattaaact
     3481 tatcttatat aacaatatct tagctactaa tataatatat attagtcttg aataatactt
     3541 tctcttgatt caatttcttt tgaaatacta gctataaatt catctaattt aatactacct
     3601 atttcacctt tatctcttga tctaacagaa acattattat cagctacttc tttttcacct
     3661 actattagca tgtatggcac tttttcaagc tgagcttctc ttatcttaaa tccaattttt
     3721 tcagctctat catctaattc aactcttata cccttatcaa ataactcttt cttaacttca
     3781 tttgcataat ccataaattt atcagatata ggaagtatct taacttgagt tggagataac
     3841 caaactggga atttaccagc ataatgctct attaatatac ctataaatct ttctatacta
     3901 ccaaaagcaa ccctatgaat cataactggt ctatgctttt caccatcttg accaatataa
     3961 gtattatcaa attgtcttgg aagctgcata tctaattgga tagtaccaca ttgccaagtt
     4021 cttcctaaac aatcttttag atggaagtct atcttaggac catagaatgc tccatcaccc
     4081 tcattaatag tatatggtag acctaactct tctaaagctt ctcttaatcc attttctgct
     4141 gcttcccact cttcgtcgct tcccatagag ttctctggtc ttgtagataa ttctaaatta
     4201 tattcaaatc caaaagtttt gtatatacca tctattaagt tagctactcc ttttatttcg
     4261 tccttaattt gctctggtaa catgaatata tgtgaatcgt cttgagtaaa tgctctaact
     4321 ctcattaatc cttgtaatgc accagataac tcatgtctat gaactctacc aagctctgca
     4381 actctcattg ggaaatctct atatgaatgt agttgagagt tataataaat taatccacca
     4441 ggacagttca taggttttat agcataatcc tcatcatcta ttttaactgt atacatattt
     4501 tctttgtaat gataccagtg tcctgaagtc tcccataatt ttctatttaa tatgattgga
     4561 gattctatct caatatatcc agcttttctg tgtatttctc tccagaattt taataattca
     4621 tttttaagtt ccataccttt tggtaaaaac atagggaatc ctggaccttc ttcaggtatc
     4681 ataaataatc ctaattcttt acctaatttt ctgtggtctc tctttttagc ttcttctagt
     4741 aaatgtaagt actcttctaa gtctttgttt ttctcaaaag aagttccata tattctttga
     4801 agcatcttat tattttcgtc accacgccaa tatgcacctg ctacactttg taatttaaca
     4861 gcttttacct ttttagtaga tggtaaatgt ggtcctctac ataaatcagt aaaatcacct
     4921 tgcttgtaga aagatattat ttcactttca ggtaaatcag atataagttc taccttatag
     4981 tcttctcctt gttctttcat aagctctaaa gcttcatttc taggaagttc aaatctttct
     5041 atttttaaat cttctttagc tatttttttc atttcagctt ctattttctc taggtcctct
     5101 ggaactaatc tatggtctaa atctatatca tagtagaatc cattttctat acttggtcct
     5161 atagcaagct ttgcttctgg gtaaagtctt tttatagctt gagctaatat atgtgctgat
     5221 gtatgtctaa aaacttcctt accttcttta tcttcaaact taaataaatt caagtcacaa
     5281 tcagtatcta taatgtggtc cagacctaca acctctccgt tcacagacgc tgctaccaca
     5341 tttctagcta atccttcact aatggattta gctacatcca taacagaaat agcattttca
     5401 aattctttta ttgagccatc ttttaaagca actttaatca ttgttttttc ctccttattg
     5461 aaataatttt tagatttttt gtaataaaaa atcgccccaa atatgtttgg gacgatatta
     5521 attcgcggtt ccacccaagt tggcgtatac aagtatatac aaccctcttg atgactataa
     5581 ggtcgtcacc cgagcacttt cacgtatagt acaaaacaaa tactgctaat aagctcagct
     5641 ccaaggtagt tttcaaatag acctattaca tgggctctca gccatagacc caaattctct
     5701 gagaatggtt tctactctac tcttcctctt caacactatg atttttaata tattttcatt
     5761 ataacagata gttatacatc aatcaacatt aatgtaatat attaattacc cattattttt
     5821 catctcaatc agctgtaaac caatattctt atatttttat attaaattaa tctcttgatt
     5881 tatagtgata ttataatatt ttcataaatt taaaattttt aaaacgtatc cacatgcatg
     5941 atagatatga ctagataaat actaaaacta atttttatta aaactaactt ctaatttttg
     6001 tactcttttt aggttttgta tacttaaata caatcaatac ttaatatagt taataagtag
     6061 tacagtaaat acttaaatac tattaataag taacacaatc aaataaataa atacaattaa
     6121 tatctaaatg ctattaataa gtaattcact caaataggta aatataatta gtacttaaat
     6181 aaatgctact tctcatatat ttaaataaac atagtaatta acccttgagc tatacctatt
     6241 aaaaacccta agacaagccc caaaaactct atatgtttta attctttctt agctattctt
     6301 attattatct cttccaattc atataaatct agttcattaa tcttatcttc gaccattttt
     6361 tgtatatcta tacgttcatt tgctttattt attatatttt tactcaattc atctatactt
     6421 tgcttaactt cagactcaat tatctctcct agataatctt gtatcatgtt ttttatacca
     6481 ctcgggataa atgaaacttt ctcatgtatt ataattttta cccttgcttt tatgtatctt
     6541 acaacttctt ccttatcttc gtcagtaatg atatttgcaa gtatttcgtc catagaaaga
     6601 aattcttctt gaattatttc tcctacattt gctgctattt ctgctcttct ctttggtata
     6661 agacctacta tttctatatt taaaataggt attttaatag gctctattgg tctaaatatc
     6721 agtcttatag caactacatt cgtaacataa cctataaatc caccaataac agctaatatc
     6781 agtatcctaa ttaaattatc cattataaaa ttactcctta tcaattgtat atttgccagc
     6841 tatattgtat taatcaagta gatattcttt atacttaata acactagtta tactatagct
     6901 ttatatacaa ttataagtct tttgtgtcga tttaaaaaga atttttttaa ttttatatgg
     6961 atagctttta tatgcttaga ttctagtttt ccataattat actaacttta ttttcaaaaa
     7021 ttgcttctac agtatctata atttcctttg agcaattatt atttaacaaa tccaatattt
     7081 ctattttttt gggacataga gttaataagg tacttattaa aaagtcctca taatttaaat
     7141 tttctcttat taccatattt ataatttctt catcatctat actgtctatc ttatttccat
     7201 ttttatcgta taaaacaaat gtattatctt ccattatatg aactttaagc aaatcaatct
     7261 tttcttcttg agtatctata aagtatttta aaactcttat aaattcatct tggtctttct
     7321 ttattaaata ctcctcaact gcaatatcac ctatagcaga aatatatttc ataaattctc
     7381 tcattctaaa tctaataaaa ccttctacat ttataaaatc attttcttct atataatttc
     7441 tcaccctagt aaatactgtt tctctcataa aaatctcttt tttagcaaat atgttcagtg
     7501 aatatatgta tatattattt ttatcttcag gatatgtacg cccatagcat tttagaatgt
     7561 attctttcaa aagtttctct ttcattatac ttattatcat actagttatt tccgttgata
     7621 tctcatcaat atttaaagct ctttgttcag ctttagtacc attaagtatt tttttattta
     7681 acacttcttg ctttgcagaa tctatcacta cttctacaat gtcattcgta tatattaatc
     7741 tatcgtttac attattattc ctcaaaaatt tcatggaaga aatattatcc ttctcaacca
     7801 aagttatcgc tcctttcttg tcatgagagg aactatagaa cctatatcta gtaaattttc
     7861 acagctaagt gtaactatct ccttgttttt actttctaca aaacttttta tacgttcata
     7921 gtcaggatgt tttttaacat ctccacaaaa agctagttta tccttagaaa tcaaccctgt
     7981 acatccacct ataaatccat aattcatctc aaataaattt atgtgacctt tttctatcaa
     8041 taaacactct atttctgtat tcttcatact tttccaaata cctttatctg atgttattat
     8101 agacgttcta tctactatac agattgagca tttagaatag ccctgctcta tatttatctt
     8161 tttaagttta ttattttcaa tataatctaa tattgctttg tcagtatact taaaattgtg
     8221 tatagcatag tcaccaacta tcgcaatatt gtaaggtata tcataagggt atctatttaa
     8281 taaattagct tctcccttaa ttatattaaa tttatatcta cttaataact ctttgtattg
     8341 attatataca ttcggcgcaa caattatatc tccttttcct aaattacaaa tacatatatc
     8401 cgggtgatat tttatgcttt catataattc tttacattct attgttttta ttatctctat
     8461 atttcttaat tttaattcat tttccattag ataactaatt cttttgtcca ccaaagctag
     8521 acacaaatcg tcatctagta taaatggttc tcttgtaaat tccatttttt actccttttt
     8581 cttttttttg ataaattttt tatgtgaata taaataaagt gtgtagcaga atttttctgc
     8641 ccacacactt attgttataa ttttatatag ttaatctaag cttaattagt atagctttgt
     8701 acagttggtt caaatttaat aaatatatct ttttatcact aatctaaact taagcagtat
     8761 attccgtaca gttagcacaa atttaataaa tatatctttt tattgctaat ctaaactcaa
     8821 tcaatatatt ttgtacagtt agactaaatt taataaatat atccttttat caccaatcta
     8881 aacttaagca gtatattcca tactgttaac acaaatttaa taaatatatc tttttatcac
     8941 taatctaaac ttaatcaata tattttgtac agttagcaca aatttaataa atatatcctt
     9001 ttatcaccaa tctaaactta agcagtatat ttttataatc ttctacatca ataattaata
     9061 tgtatctttc actttgttat actctttttt tatgtattcc aaaacatctg gtggtatatt
     9121 tctactgctc tttgaagtca agccaagttc tccatctttt attttaaatt ccattacttt
     9181 acttccctta aaaccatctt ttgcaacgtt ctttatcagt tcatatacag gttgttctac
     9241 atcttttata attgaactta ttacattatc tggagccata tcgtattggt ctttattaat
     9301 agctataact ttacctccat tttctcttgc tacctgaata gctcttttac tatcatcctc
     9361 tgtagctgaa aatacaacat ctctatcaga atctctcatt tcctttgcaa tagttctagc
     9421 tgattcaggg ttttcaaata tatttgaata cttaactagt aactcagcat ctttatttga
     9481 agttttaagc ccctttctaa atccagattc atacttatct ctactagaac cctcaactcc
     9541 tcctataaaa ccaaccttcc cagtatcagt cattttacct gcaataagtc ctgctaaata
     9601 tccagtaaca ttatcttgaa atgatacaga aattacatta gctggctgaa ctttataagt
     9661 atagtcaact attgcaaatt gctgtttggg atattcagta gcagcttctt taattggctc
     9721 tgcaaatctg gctccaactg ctattatcaa atctggttca tacttatgca gtttttctat
     9781 actctcttta aaacttttag aagtctttgg tttttcaagt tttatcctaa catcaaaatc
     9841 ttcgtcagcc ctttttaagg ctgatagtac attgttatta tatgattcgt tatttaagtt
     9901 ttcggtatct aacaatactc caatagtttt tcttacatat gaatcatctt ctgtgtcatc
     9961 ttctttattc ttacttttac tatttgattt atccttttct gctgaagttg gcaaactttt
    10021 agactcactc tgtttcgatt tagcactatc tatattagaa ttattcttat ttactttatc
    10081 aaacccaaaa tcaaaattac atatagctaa tataaaaatt gtaaaaacta ctacaaagca
    10141 agccatcaat atccttttta ttttcacaaa attcactccc tgatttagat aggtctgacc
    10201 tacctctgca tatgtctttc tatatatgtc tattataaca tccaattcac ctcataacta
    10261 aagtcataag tattcttgga tattatagta gattatttat tgttcttatt aacatattct
    10321 aacacatctg gaggaatatt ttgagaacta ttttgggcaa gcccagtact tccagactta
    10381 actgtgtttt ctataacttt tccgccttta taatttcctt ttacaaaact ttgtatcaga
    10441 ttataagtag gattctcaaa atcttttaca atagaactta taacattttc tggagctaac
    10501 tcatgttggt ctttattcgt tgctataact tttttatttt ttgcccttac tgcatctatt
    10561 acagcttttg aatcatcttc agtagtagaa aaaataatat ccactccatt atccatcatt
    10621 tttttagcta tagattctac tgatttgcta tctttaaaaa catctgcata ctcaactgaa
    10681 atatccttta tactactatt agaaaattta acaccctctc taaaacctga ttcaaattta
    10741 tctctactag aactctttgt tcctcctata aaaccaacct tatcgctttc agtcattttt
    10801 ccagcaatta atccagctag atatccagat ttattatctt cataagaaat tgaagttata
    10861 ttagaaggtt gcttgtcata ctcatagtct ataattgcaa attgttgctt tggatatttc
    10921 ttggctacca tctccaatgg ttttgcaaat ctagctccta cagctataat taaatcgtaa
    10981 ttgtcattac ataaaatatc tatactatta gaaaaagttg aggaatcatc tgattccact
    11041 ttgtttgtat ctatattaag tttcttttga gcattgttta atgctaataa agctgaatta
    11101 ttcatagctt cattatttgt tccttcaata tctagtatca ttgatacaga tttttttgaa
    11161 ttacttttat cgcttatatc acttttatta tctttgctag agctaggatt attgcttggg
    11221 ttattagcac acccaaccaa cattccagct atcattgcta cagttaacat caatatcaat
    11281 attcttttga aacgcattaa atttcactcc tcatacattt acgatatttt tatatcctat
    11341 ttacttttac atcctattta cttttacatc ctatttactt ttacatccta tttataattt
    11401 ttttatatac aatttacaag tacattttga aattttttta ataaatctta ctataaaaaa
    11461 gtgtgcaata gattcttatc tatttacaca cttccctaca aactaaatct aatatatcaa
    11521 cacttaattt catccaaaat aaatccaatt taacatctca ataattaata ttctatccta
    11581 atttaataaa aaaataaata atgtcatcca aaaatatatt atttattttt taagcatatg
    11641 ataccagtaa caccaggacc agcatgtgca cctatacaca caccaatttg gaaaaatcta
    11701 atttctttag gtcttaattc atcttgcata accttagata attgttcttt ttccttaaaa
    11761 tcatcactat atcctatata tacaatttgg tctgataaat catcaccaca atttgatttt
    11821 atcaattcca tcatcttaga aattacattc ttctttcctc ttacttgaga tatttgcgaa
    11881 actaatccat ctcttatttc aagaatcggt tttatattta atatacttcc tattgctgcc
    11941 ttagtagatg atattctacc tcccttttgt aaatattcca atgtatctac tgaaaatata
    12001 acaaaagcct tctcttttaa ttcatccaaa acaggcaata tttcagcaac agactttcct
    12061 tcacttgcaa gttctcctgc ttttattaca agtaaaccag ttcccataca aagcaagtta
    12121 gagtcatatg tatatatttt accatctaca tcattctttg ccattacagc actttgatac
    12181 gtacctgtag ctgtggcaga ccctgctata taaagtatct ctctatcctc atttgtatat
    12241 ttctcaaaaa tttccttaaa ttgggcataa gtagcttgag aagtttttgg atatacattt
    12301 tcttctctaa gctttttata aaattcatct ccagatatat caattctatc cttgtattct
    12361 ctttcctcca gtataactgt taatgaaact atatctatat catatttatc taacaaatct
    12421 tttggcacgt ccgataaact gtcacagatt atctttagat ttttcattaa gtatgctcct
    12481 ttctcattta ggcttgttga aactacctca tatttgggta tcctatttgt cttaaagcct
    12541 cgtacactac aatagcaact gaatttgata aatttaatga cctagctttt tcaacatcca
    12601 acataggcac tctaatacaa gtatccatat ttgctttcaa caaaggttct ggtaatccct
    12661 ttgtttcttt cccaaatact ataaaacaat tttcttcata tttcacatct gaatgtgact
    12721 gtttagcctt tgttgtagaa aaaaagtatt tactatttgg atacttttct tgtaattctt
    12781 caaagctatc gtaatattgt atatcagcta tatcccaata gtcaagccca catcttttta
    12841 ggtgtttatc atccaatgaa aaacccagtg gttttactaa atgtaaagtt gaacctgttg
    12901 ctgcacaggt tcttattata tttcctgtat tttgaggtat ttctggttct actaatacta
    12961 tatttaatga cattttaatc ctccctaagt atcgctttta tttatcaaat tttattttat
    13021 aaacagaata acaataatat tatactatta tataaaataa tgttaataat aatttttatt
    13081 tcatgtatat aatagttttt tatctaacat tttcacaagt attattatat cagaaaatcc
    13141 ctcttgtaca acttactttc taaaagttat ttcgtttcat taagttcttt ataataatta
    13201 caatcttctt ttattgggca acttgcacat tctggatttc tagctttaca cattcttctt
    13261 ccatgaaaaa ttaatacatg atgtgagtgt gaccatcttt cttttggtat agcttccata
    13321 agtgcaaatt ctgttttttg aggatttggc tcgtccacta ttcctattct attgctaact
    13381 ctaaatacat gagtatctac agctattgct ggatgattaa aagcgttact aagtacaacc
    13441 cctgccgttt ttcttccaac accaggtaat tttataagct tttctaagct atcaggtact
    13501 tcaccatcat ataattcaca tagctgttca gatgtatcct ttattttttg agacttgctt
    13561 ttgtaaagac cacaactctt tatctcttta ctaatttctt caatgctcaa attagcaaag
    13621 tctctagctg tgttgtactt tttaaacaac tctgaagtaa ctttattcac tcttacatca
    13681 gtacattgtg ctgataaaat agttgctatt aaaagttcaa aggctgtccc ataatttaac
    13741 tcacatttag catctgggta cagtttttct aactcgtcta aaatcttatt tacgtctttt
    13801 tcatttgctg actcattttt aattttaaac ttacttttag tttctttact tgttttttgt
    13861 gtagccttat tagaactact cttctttgtt tttttctccg tttcaccttt tttagtactt
    13921 tttttactta ctttgatact ttttttatct tcttcaatat ccataaaatt ctctatatct
    13981 ttctcatcaa ttatctcatc ttttttacca atcattttat ctatttcttt ttcatttatc
    14041 tcttccttct caattatatc tttcttattc attccttttt tatttatctc ttccttctca
    14101 attatatctt tcttatccat ttctttttta tttatctctt tcttctcaat tatatctttc
    14161 ttatctattc cttttttatt tatctctttc ttctcaatta tatctttctt atctattcct
    14221 tttttattta tctcttcctt ctcaattata tctttcttat ctattccttt tttatttatc
    14281 tcttccttct caattatatt tttcttatcc attccttttt tatttatctc ttcttccaaa
    14341 attacatctt tttcatttat ctcttttaga tttacatttt tcataattat cccccttcaa
    14401 aataccaatt tataaaacgc tatttataaa tagtttaatc atatcaacaa aaaaataaac
    14461 atcaatatat aaaacataca aaataagaat ttaatttata tatatttaca aaaaaagcaa
    14521 aaacctatta aagttcttgc tttttattat acataaatac ccattaaatt ctataataaa
    14581 cttattcttt tgacacagtt tgtatcttgc tgaaagatat taatttttct tttaccaatt
    14641 tctttatttc ttcaaattta acatctgtca atatctctat agcctcttct actctttcaa
    14701 cagtatatat cttaaatttt ccatctcgca ctgcatcatt aacttcatct gataaaacga
    14761 gatttctttg attttttcta ggaattatga cgccttgctc accatttaac cctttagttt
    14821 tacatataga ataaaatcct tctatctttt cacttatacc accaactact tgtatatcac
    14881 ccttttgatt tatagaacct gtaacagcaa tattttgttt aattgatact ccactaagag
    14941 atgataatag tacatataat tctgcagaag atgcactatc tccatctatt ccaccataat
    15001 tttgttcaaa acaaacatat gcatttagtg acaatagtaa atcctgtgca aaattctcag
    15061 aaagatagcc acctaatata agtactcctt tgttatgtat agagccactc atatttactt
    15121 ctctttctat atttactatg cctttacttc ctgggctagt ggtcgctgta atccttgaag
    15181 ctctaccaaa agagtattct cctgtactta agactgacaa accatttatc actcctactt
    15241 ttcttccctc tgtttctatt agagtaaatc cattttcaat tgattcatcc atatgtgttt
    15301 ccactctatt gattcttttt ctcttttcac ttattgcttt tttaacatca cactgctttg
    15361 tatactccga atttctaaac tctgcataag cacttccttc tattacaact tccattattt
    15421 tattaaactt agttgataat ttttctaaat caccagataa tctagtgcta aatttaataa
    15481 cctcttcaac tgctgattta gtaaaatgcc ttaaattatt cttatcacat tggtatgcta
    15541 taaatcttgc tattccttct tcattatctt catttttatc catttcacta tcaaagtcta
    15601 caaatacttt aaaatatttt tcaaaatctt catcatatct atataaaata tcatatatat
    15661 agtggcttcc aatcagtact aatttaacat ccaatggcat attttctggt ttaattgctg
    15721 tttgtgtttc caatattact tttttagtct gcaaagtctt tttaagaatt tcccaagaca
    15781 ttgtatattt tagtaattgg tctgcataaa gtactaaata accaccatta gccctatgaa
    15841 atgctcctga taatagtttt gtgaaatcag tctttatatt tccatttgca taatcatact
    15901 ctgcctttcc aaatagattt gctggacttg ggtttatctc tactacaaca ggtgctgatt
    15961 ctttattctt tgagcttcca ttgtctacaa ataggttaat tttatattta ataaaatgct
    16021 ctttatcata cttatctttt aactcctctt catctaaata gaataaatac atatattcta
    16081 ttatatcttt ctttatattt tccagataag tttgaatctt atcataattt tcatattttt
    16141 cacacaatct cttgatatga ggttctacta caagtttagc tatctcttct tcaagctcta
    16201 acactgcttt ttcagctatt tcttctaagt ttctaatttt atatacgacc tgtatcgcca
    16261 tattttctag ttctctttta gctttgtaaa actcttcatc agactcatca ctttcatctt
    16321 cctcttcttt caaagggata aaaactattc ccattttact ctgttttaat ttaaatcctt
    16381 tttcttctcc atatttttta atttgcttca aaagcatatc tttttctatt tcatattcat
    16441 ccagaagttt atttttttct atttcaaaat tttcactttc aaacgcattt ttaaaatctt
    16501 ctaaaagact ttcaattaat ttctccatat ctttcttaag ttctcttcca aacccctttt
    16561 ctaattcaac tataataggc tctctagggt tttcaaaatt atatatataa caccaatctt
    16621 tatgcgtatt ttttttggat gcatactcat ttaaaacctt taaggcataa gtacttttac
    16681 cagttccagg ttcaccagct atatatatgt tgtacgctgg attatttatt ttcaacccta
    16741 attccatagc ttctacagct ctttcttgac ccaatatata atctagtgga tttatttcag
    16801 atgtattatt atatttcaat attcccccac ctccccatat ttaactttaa tgatataata
    16861 tgacttttac acaacaagtg ttaaagtaaa tacacattaa agtatatgaa acagactctt
    16921 attattagtc atcatactta tctaaaatta tttccatatt tctctttatt atatttctac
    16981 ctctccagct aaaagctcta tctccatatc tccttttaaa ttctttattt gaaatatttt
    17041 gtatctcatc ataatccaaa taatctatta tattttcttt aaattccaaa atatgagttg
    17101 ttggtatttc aacattatgt ggacatactt cttgacaaat atcgcatcca aatacctttt
    17161 tgccattctt taaaacaact ttttctttct ctgacaaatc tccttttttt tgagttatat
    17221 atgataaaca ttttttgggg ttcatatcat aatttcccaa tatagcattt cccggacaat
    17281 attttacaca cttaccacat ttaaaacaac ttttttctag tggtttatct tcttcaaatt
    17341 tataattatt tactatatac cctataaata cgtaagaacc atattcatca gttatgatat
    17401 tattatttat tccaaaatat cctattcctg ataaataagc taaatacctg tcaactaatg
    17461 gtccattatc agcaaataac ttgtatttaa aatctgttac tgttttagaa atataatcac
    17521 aaatttgttg taaaaagtcc tttactacaa tgtgataatc ctttccatga caatattttg
    17581 ataaatttga atttttattc ttttcttgtc tatttatatg atatggaaat gcacagacta
    17641 ttatagagtt agcatccttc attatatgtc ttgggttaat tctgctctca attattggtt
    17701 cttccatacc agttaaataa cctttttgtt gtctgttctt aagtatcttt tctaaattat
    17761 catatttatc tacccctgct actcctacac agtttaatcc tattaaatta caaaatgctt
    17821 ttaattcctt attatccata aaattattcc tttttaatct aattgacttt ttaaatttat
    17881 ttaatttttt tagtcttttt aaccttttct agctactaac tcttttaaat acttaatctt
    17941 tttagctatt caattttctt acctgcttaa ctcttttaga tacttcgtct ttttatctat
    18001 ttaatttttt tacctactaa ctcttttagg tacttcgtct ttttacctat ttaatttttt
    18061 acctactaac tcttttagat acttcatctt tttacctatt tagtttttta cctactaact
    18121 cttttagata cttcatcttt tttatttact tatttaactt ttttacctac taactctttt
    18181 agatacttag cctttttcat ttacttattt aactttttta cctacttaac tcttttagat
    18241 acttagcctt tttaatctat tcaacctttt ttacccactt aaccttctta ccttttaata
    18301 taaactctaa aacttcaaat atcattagtt atattttgac attctttcta tagttaagca
    18361 aaaagattga ttttttctta taattaatat cccatttaca ttgccattta ttaagtcttt
    18421 acttgactta tatggatttc tttttactct ctttactaaa cttatactta ttaatattat
    18481 gaaggtctta taatagtcta atatgaatat gcccatcata tatcaaattt taaaatttgt
    18541 aagcaaaata cttatcttat attactacat ctaaagtgga aaattttaca aacaagctct
    18601 gtaaaaacac tttaaataac aatttgcttt taaatcatat acagattata ataaatactg
    18661 tataaggatg gtgaaaaatt tgattaaaat aacaattcca ggtagaccta ttagtaaatc
    18721 taattttaag cttcataaca taaatggtca agcatggatg ccttcaaagg gaaaatattc
    18781 taagtatctt gcatacgaaa acatgattgc aggttttata aaccaacagt atcaagggga
    18841 aactgttgaa gaaaatctaa taacagtctt gaaattattc ttcccaaata agagaatggg
    18901 ggatttacat aattatccaa aaagtatttg tgatggtatt gaaaaaagtg gaataataaa
    18961 aaatgataaa caacttaagc cagtactttt atttgatttt atagataaag ataaccctag
    19021 ggttgaaatt gaactttatc cagtatctaa atacgatata tcctataata tttttgaaaa
    19081 ataaagattt tatgtgttat tcgacattat attgatactc cagtatttga aactatacta
    19141 atacaacaat aataattgtg ttatgtctat actcaaacaa atgtttttaa aaagcattaa
    19201 gtaaatattt aataagtatt aaacaaatat taaatttata taatagctat aactatgtaa
    19261 atttaatatt tgtatataag accacatcta ataaaaagaa atcggagtaa atttaataca
    19321 ccgatttcaa taaataaaat ctatcctagc ttttcaacaa cagtcttaag catttctctt
    19381 ataggaagtt catatggaca tctactctcg caaagcccac agtcaataca ctcagtaggt
    19441 ttaacatcca taacctcata tttttcttta gcccactctt ttaatccata tctagtataa
    19501 taaccttcac ataaaaaact caatggtata tttattccta cagcacaagg catacaatat
    19561 tcgcatcttc tacagaattt tttacctaaa gaatttctta tttcttcaat ttccttatta
    19621 tctttttcat ctagcacaag attttcaagt acagcgacat tttgtctaac ctgttcaaca
    19681 ctctccatac ctggtataac tacatctatg taatctttag atagtatata tttaatagcc
    19741 agtgttgcat tgtctaaagc acctccagct aaaggtttca ttactattat cccaattcct
    19801 ttttcatgag cttttttaaa cacttcatct gcttgtcctt caactatatt gtaagggaat
    19861 tgtatagtgt caaattttcc atcttctata gctttttcta tagtatttaa attgtgacta
    19921 gttataccaa tatgttttat cttaccttgc tcctttgcct ctaaaagggc actataagcc
    19981 attttatctt taaaaagatt atcatactcc tcttctttaa cattatggaa ttgatataaa
    20041 tctataaaat cagttttaaa attatttaaa cttatttcaa catctctctt cattgaatca
    20101 taatctctgg acatactttt agtagctaag aaaaatttat ctctttttcc ttcaatggca
    20161 attccgattg cttcctcact tattgtatac cctcttgcac tatcaataaa gtttattcct
    20221 tgtttttcta actcatttat aactaagtta gtatcatctt gagtaatcct ttgtattgga
    20281 atgcccccaa agccaactct ctttattttc atgttagtat tgcctaaatt tctcatatct
    20341 ttccccacct aacttttaat aattttttat ataatataaa tatgtcatct ttaattatac
    20401 aacaaattat gagaatcttt gcaatatatt tacatactat tcatagtata attatatttt
    20461 atatcagtct attcataata taatcatact ttatacccag ttaatttgta tacaattttt
    20521 gttattccta tccattaatt taaattatca catttcatga ttgtatctcc accctaatta
    20581 tgttgagggt gaagtatttc acatattttt aataaaggtt tatttactag atagtatttc
    20641 ttttatcatt ttaagctctt tcttgtgacc ttcatcatca aaaggagttt ctaagaaaaa
    20701 tggtaaatgt tttagactag gatgttccat aaaatcaatt aatgctttta atcctatctt
    20761 tccttcccct ataggagcat gtctgtcttt tttatctcca aatggcatca tactatcatt
    20821 tagatggaca gttttcaatc tttctatgcc tataacctta tcaaattctt ccaaaacccc
    20881 atctaaatca ttcactatat cataaccagc tgaaaaaata tgacatgtat caagacacac
    20941 acctattttt tctttatgct caattttgtc tattatactt tttaattgct caaatttaaa
    21001 acctatttca gttccctttc ccgacatagt ttcaagaagt atagttatat tttcatcacc
    21061 ctttatggca ttgttcaatc cttttactat tctatctatg ccaaaatcta caccaccacc
    21121 tacatgactt ccaggatgaa aacacatgta ttcaattcct aatgagtcca tccttcttat
    21181 atcctcatct atcacccttg ttgcaaattc gtatacatca tcctttgtac cacccagatt
    21241 catagtatat ggtgcatgtg caagcagtgg tgcaaaatta ttttcttttc taatttcttg
    21301 aaatttaatt atatcttttt catcaaattc tttagcattt cctcctcttg gatttctact
    21361 aaaaaattga aatgtatttg caccaatata tacagctgtc tcagccgcat tagcaaatcc
    21421 ttttgctatt gaaagatgtg ttcctaattt aatcatatta atctcctttt atttgtacta
    21481 ctacttgtac tcaattttaa ttttgaacta ctccacctta actacattta gccaacatat
    21541 gaagatggag attcctattt gatagtactt tttcactaaa aattcgtaag ctctaaggga
    21601 tgttctatcc caactaatct cagtcctctt ttaacatatt tctagcattg atttaattta
    21661 tattaatttt taattttaat atttacactt taattatacc cattttaatc aatttcaaat
    21721 attataatct tacatacttt gtatattatc taagcacttc ttagatagtg tatacatctt
    21781 acactataca tattatttac aaatacaata ggtataaaaa aacaaaaaaa tagagattaa
    21841 aaatcattgt tttacccata ccaaaaacta ttttttgatt attaagtaaa ttttgatgtt
    21901 caatctctaa tattatatct ttaattaatc cataattaat tctctaacta ggacattcct
    21961 cctcaagagt aggaactata accatagcta tatcatactt agaaccttca acattgtgtt
    22021 gtcttttatt taaaatttca tctatctttg acttcatagt gtcactaagt tcaactaatt
    22081 catcatgagt aagagaaata tcatgataat caactatatt ttcattttct aaaacatctt
    22141 cctctgctgc cttataaaaa acttcactca tattttcaaa ttttgatatg tacaattctt
    22201 ctttttcttc cccattgtct aaagaaaaat taagtatcct attccctata accacatttt
    22261 ttgcacttgg ataatagtac ttttccacaa tccccgactt tattttttcc tcaactaatt
    22321 ctaaaatacc aactttgtat aacattttta tatggtagtt tatttttgca tgaggttctt
    22381 ccaataattg agataattgt tttgctgaca atggcgattt gtcaaatgct tttagaatat
    22441 ctattctacg tggatgcgca atagccttta tgcactccaa atctcgtaat accaatacct
    22501 ctttcattga cccctcctaa aaaatttatt taattcatat ttctttacaa tttaattata
    22561 tattaaatta tatgttgttg tcaaaaaaat cctttcttaa tattttaaaa aatatttaat
    22621 ttgagtttat ttgacaactc ctctaaaact ttaactcctg cgacgctgtt accttttttg
    22681 tcaagcgcag gtccataaac accaatcccc atgcgtcccg gcacagaagc cattatacca
    22741 cccccaactc cagattttgc aggaatgcca actttaatag caaattcccc agaagcatca
    22801 tacattccac aagtcatcat aaatgtcttg acaatcctag aaaccatttc actcattaaa
    22861 tgctcaccat tttctatatc tactccataa tttgcaagat ttattccaat tctcgctaaa
    22921 tctacagaat ctatctcaat tgagcattgt ttaaaataaa ggtctagaac atcttctaca
    22981 ttccctctga taaatccatc acttttcaat aagtaagcca tagctctgtt tctatctcca
    23041 gtcatttttt cagacttata gacatcatag tttattccta tattatcatt ttttgctaac
    23101 tttctaaaga aactaagcat tctttcttct ttttcttcta aacaactccc atttataagg
    23161 gaagtggtta ctatagcccc tgcatttatc attggattac agggtttttt tgtgtcatta
    23221 atttcaagtt tcattattga attaaatggg tccccacttg gctccattcc aacgtttgaa
    23281 aaaacgtctt cccaatcatt atccataagt gccatagcaa gcacaattgg ttttgaaata
    23341 ctttgtatag taaactttgt gctacagttt ccagcactat aaagattatt ttcgctatct
    23401 atgatacaaa ttcctaaatc atttcttcta gcgtttttta attctgggat gtaactagcg
    23461 acttgtccat aattagtata cttcttatta gaacttataa tttcttttaa taatgtctca
    23521 tctaacgtat tcatatgcac ctcttatatt atgttatata ttctatttta gcacaagttt
    23581 atactataat aaaacaatgt taaaaaaaat tatactttaa aattattttc tacaagaatc
    23641 aattcatttt tcaaacaatt taaatagttt aaagagctta ataatttagt aattcaataa
    23701 tttaacaacc tagtaattta gcaatccagc aatctaataa tccagtaatt taaattttta
    23761 taacaccaaa aatttctaac ccaacacctt ttactctttt actcttttac tcttttactc
    23821 ttttactctt ttactctttt aaaaaataat cacataaact aacaaaatat taaacaaaaa
    23881 agtaaaattt aaaataaaaa gcttgcttca tacaaaagta taaaacaagc ctttttatat
    23941 atcaactcaa actttaaaat ctgtatcaat ttaattctcc actttacact taatatactt
    24001 aacataaacc aataacacta cttgctatgc catttaatct tcataaaaca atctataata
    24061 cacacattaa tcaactattt tacttcctcc aataaattcc ctaagaattg aaatacctgg
    24121 tatgtcagaa gtatcgtcca attcaacaaa atactgcaaa aactttagta atctagtagc
    24181 ttcaatatgt gcaggattat cttcctttat ctcttccaac aaaggtttcg caaatcgttt
    24241 taaaactgcc aattcatata cacaagcaga gttaaatata gcatctgcct cctcttggta
    24301 cgggaatata ttcttctttt ctcctcttct aactgatgcc cattgtaaaa tagtattatc
    24361 agcactatat cctctaaaat tatagtctct aacaattctt cttatcattc tcaaatcagc
    24421 agtagggatt cgattatggt catccaaatt tatttgagta agggcactta tgtatatctt
    24481 aaatttatct tcatctggta tagatgatgt taaaatagga tttagcccat gtataccttc
    24541 taatataatt ggctgatttg aatctatctt tatcttttta ccagtgtatt ctctcttacc
    24601 ttctttaaaa ttgaatctta tatcatcaat ttcttcacca gctaaaagtt tctttaagtc
    24661 taagttaaac ttctctaaat ctattgcata aattgattca aaatcataat ttccatattc
    24721 atctaaagga gtatgttttc tatctataaa ataatcatct aaagaaattg aaataggatt
    24781 taaattattt actctaagat gtattgataa tctgtgagca aaacttgttt ttccagatga
    24841 agatggagct gctattaaaa ctactctctt attgccatcc tttatcatat ccgctatttg
    24901 agatagcttc ttttcatgca atgcttcaaa tgtccttatt atatctccat attcattgtt
    24961 ttctattatt ttattaagag atactacctt gtcaattccc ataagtcttg accattcttc
    25021 tgcttcataa tatacacttg atagcttagg ttgaggtaca aatttcatag gaagagtctt
    25081 atcttcttca ctaggtccta aaattataac gcctccatta taaagcttaa tatcaaatga
    25141 ttttatataa ccagttgatg gcaacatata accataaaaa tggtctatat agtttctaca
    25201 cttatatact ttagcactat catactcttt gtatttcaaa agctctgcct tttcatacat
    25261 ttcattattt tcaaagatag aaatagcttc atttcttgta acttcaattt tttctataac
    25321 ataatcgttg tttactatct ctttcatctt gttttttata ttttcaacat ctgcttcttt
    25381 aagctttcta tctatatgaa cttcacaata tagcccatct gatagtgaat gttctattgt
    25441 aactctgcta tcccaaaaga tttctctaca tgccattaca aatataaatg acatgactct
    25501 aaagtaaact ctctctccat cttcattagt agtatctaaa aaatttatct cacaatcctt
    25561 cttaactcta caatttagct cttttagttt attgtctaca actgcaagtg ttatataacc
    25621 cttatgctca tcacaaaatt cttttgctat atctcccaat ctgattccag gggaattttc
    25681 ttctaatgaa tattccttat cttttccttc tatttttaag tttatttttt tcacttcaac
    25741 atctccttcc ttttgatgaa tataaatttt aattaatgag gcatatcaac aagataaaga
    25801 gaggtattta accctctcct acaatattat tcaatttact tatagtatct tcaatgtctt
    25861 cgtaatttat ttctaatact aaatattctg catctaatgt taagacctct ttaatcccct
    25921 cttcagataa aattcctctt cctataccaa catgtgtatc attgatacca tcattatcac
    25981 ttaagtgtat cagtcttatt ttatccttta agttctttac ataagcatcc tcatcaatta
    26041 aacagtgtcc agtatcgtaa caaaaacaaa tcttagaatt tttaatcctc ttaaatatat
    26101 attcaaaatc ataagatata tttccaatat ttgaaaaatc cccacctttt gaataagtat
    26161 tctctataca tacatatgaa tttgtattta atttatctaa aaaatccaca ctatttccta
    26221 aatatttgtc tctattcttt ctaactctat ttgtcataac atatcccaaa tgaaggttaa
    26281 aataccttaa atcaaatcct tttagttcaa attctatctt ctcaataaaa tttatccatg
    26341 aatttcgtat atactctatg ttttcgcaag tatttaattc cataggcaag tgtatcccta
    26401 tagataatcc taacttagaa attctctctt tatatttaca taactcacta cattcagata
    26461 tattgtcaat tccaatctct aaatgagtta tttgctttat actctcacaa atgtttaaag
    26521 cctcctcaat attaaacaat aaggacgcta taccaactgc catacaaatc acctactcaa
    26581 aaatacctat atctgtaaaa ggaaatactc ttaaaataac ttttccttta atattttctt
    26641 catctactaa tcccacttct ttatatctac tgtctaaact aacttctcta ttgtctccca
    26701 tcgcaaatac ttttccctta ggaatcacca tatcaatatc gccttcagta taattatcat
    26761 gtatatatga aacttcattt aataacttac catttatata aaccttagaa tccttaattt
    26821 ttagatggtc accaggaaca cctataaccc tttttacaag ctcttttttc cttccattct
    26881 cttgtaataa atcagtctta aatatcatta tatctccaca ttttggttct gataacttat
    26941 atgtcatcct gtttgctacc aaataatcat gtgatttaag tgttgggtac attgattctc
    27001 catttactaa tgttggtttt ataaaacgag ttataataaa tgcaaaaaaa agtgcagtaa
    27061 taattatttt tatccactct acaatctctt ctttaatagt ttcattcatt cacaaattct
    27121 cctttatagt tatattatct ttattgataa tgtctcttaa acactatctt ttagataagt
    27181 ctactaaata aggtgttgtc ttttttatat agacaactat tgtgtatggt ctggtgattt
    27241 cagctaatca gcgattgctc caaattttat atgtttagtc aatagttcct atcttagaaa
    27301 atggatacaa tctgactaga acctttccta aaatggtatg ctcgtcgacc aatccaacct
    27361 catcgtatct actatctaaa cttttttctc tattatctcc cattgcaaat aattttcctt
    27421 ctggaactac gatatcaata tctccatcag tacgattatt atgtatatag gaagtctcat
    27481 ctaacaactt atcatttaca tataccttgg agtcttgtat ttttacatgg tcaccaggaa
    27541 cacctataac tctttttact aaatcttttt tctttccatt ttcctctgtt aagtcggttt
    27601 tgaatactat tatatctttg tattttggct ctcctacctt gtacgcaatt ctgttaacta
    27661 tcaaataatc acgttcaact aatgtaggat acattgattc tcctttgact attgttggca
    27721 ctataaaacg agttattgca aatgccaaaa caagagctat gacaatcact tttatccatt
    27781 ctacaacttc ttttttaact gcttcaccca ctaaaatcgt ctcctctgtg ttaaatatta
    27841 agtcaatcta cagcaaaata atctaccata aacctacaat ataaatatta tacttctttt
    27901 ttctaatagt ttaaaatact tttctaagac ctttaggata atgattctta attacaccag
    27961 aagattcttt tccccaacct aaaggtattc cttcaaccga aaccaaaacc catcctctac
    28021 tatcattaga atttacaaca tcccctttta aatatttaag aattgattca ctctgtacac
    28081 tgaagttttc aacatttttt acatcttcaa cttttaagta atgagatagt gcatgagaag
    28141 gctcaaatct attcttcttt aaaaccccta aatgcaaacc atatctcaat acttttagtt
    28201 ttttcgtatc tggatatatt tcaggaagta ggtacaaatt ttctcctctt aaataaaatt
    28261 tatttttttt attactataa aaatcaacct ttaaaaattt cttttcaaac tccctataat
    28321 cctttatttc tttatctaaa ttttttattt ttaattcttt gacattacat tcttcttctt
    28381 ctaatttttt tattttggca acaaaatgac cttctccctt tatcttatga ggccataatc
    28441 tttccatttc aataagttct gcatgtggat attcactgat aaactcattt ataacatgct
    28501 cattttcctc ccttgaaaaa gtacaagttg agtaaattaa aatgccatcc ttctttaaca
    28561 ttttatatcc atctcttata atctcttttt ggatggattg acattctact acctttgcat
    28621 aactccaatc tgatatggca acctcatcct tcctaaacat accttgccca gaacaaggtg
    28681 catctataat aaccttatca aaatacccat taaacgtctt tcttaagcta ttagaatcgg
    28741 tgtttgttat aatacaattt ctcgctccaa atcgctctaa attttcccct agagccttaa
    28801 ttctactagc attaatttca ttagaaacca ataaacctgt atcgtttagc ttagatagta
    28861 tatatgtaga ttttccacca ggagcagcac acatatcgag aactttttca ccctctttaa
    28921 tatctgcctt tggtattaca ctcattgcag aaggctcttg caaatagtat gctccagcct
    28981 catgcagtgg atttctacca ggtctgtcaa ttttatcatc ataataaaaa ccttcttctg
    29041 cccatggtat ttgattcaaa tcaaacaact ccaaatcaaa taattttttc ttgtcaattt
    29101 ttaaagtatt tattctaagc ccagtagtct tactttcctc ataacttttt ataaaatcat
    29161 catattcatc ttttagtatt tcttcaatat cttctaaaaa ttcatttggt aattctgtca
    29221 aatctataat cccccttcaa tctgctttac ttgtgtgtca tttattatac tttaattatt
    29281 tatgtctttc ctttaaattt tatttcttct tctttttcct aagattaccg aaaaacactt
    29341 ttttagagtg attcatatat ttctcaagtt tatcaagatt tatcttccac aaaattatta
    29401 cataaactat aagtaatata atagcccatc tatattctat catcaatatg aaatcaaaaa
    29461 ctccatgtaa taaaattgga attaacactg ccataaacaa atactcacgt cttttatttt
    29521 tatttccctc aaatttatac ttagaaatat agtagcccat agtaattgca aacattacat
    29581 gagctggtat agagataact gccctattaa taccaacttg cagtgctaga tttctacttt
    29641 cagaaaaaat ataaaccata ttttcaattg ttgcaaatcc taaagctaaa aatacagagt
    29701 aaataatacc atctaacttt tcagtaaagt gtttttcttt aattagggca ggaatcagta
    29761 tcagagcttt tacaccttct tctacaagtc ctgcaactac aaatgataca tatattagtt
    29821 ctgaataccc ttcaaataca ttaaacttca tcagtaaatt ttctaaaagt ataattataa
    29881 cacttagaaa agcacctatt aaaaaaaatt taattagatg gattaggggt tctctacaat
    29941 atctatcttt agaccttatc caaaacattc ctatcaatat aggaactatt gctaataaaa
    30001 ataaatctag cttcatagat tattttcctt tcaaaatttt tgatttattt atgatttata
    30061 tcatctactt atttttaact tattcgtgtt ttaaatacat actaaaatat acattaaatt
    30121 attttaaatt atttaaatac aaatatactc aaatactcaa aaaaatttaa atttatatct
    30181 atattattta acaaatttta agctatattc atatcttgaa atataaggga actaaattca
    30241 tttaaagaaa gggtgatttg atgcaagatg gtttcttaac agtaagcata attgatgcta
    30301 ctaacaatag acctattcaa aatgcagtag taaacatata ttcaatgtct aatggtagcc
    30361 aaagctcatc aactttatac caaaacctaa gaagtaatga atctggtcaa gtgactggtt
    30421 tagtattacc agcaccagat gtagattact ctctacaacc atctgatgtt agaccttata
    30481 gccagtatat agtggaagcc atagcagatg gatatgagac agttgtcata gaaggaacac
    30541 agttgttagc tacaattgaa gcaagacaag gagttcccat gtctcctaga acaagaagta
    30601 agcgttcttt ctcaagacaa agtgagttga tttttgacat aggagaacat actctatatg
    30661 gtacttatcc tcctaagatt ccagaaagta acttaaaacc attaccacct cctactggtt
    30721 tcgttgtatt agataaccct gtagtgcctg aatttatagt agttcatgat ggtttgccag
    30781 aagattcatc agctccaaac tattggattc catttaaaga gtacattaaa aacatagcat
    30841 catctgaaat atattcaact tggcctgaac agacaattta tgcaaatgta atagctataa
    30901 tatcatttac tttaaataga gtctttactg aatggtatag aaataaagga tataacttta
    30961 caataacttc aacaacagca tacgaccata agtttataaa taatagaaac ttatttgaac
    31021 caattaacgt agttgtagat gctattttta atacttttat aaaaagacct cctacatcaa
    31081 gacagccact attagcacaa tattgtgatg gacaaaaatc ccaatgtcct gaccaaatga
    31141 ctcaatgggg cagtaaagac ttaggtgacc aaggatatga ctatgagagt atactaagat
    31201 atttctatgg agatgagata gtatttgaaa gagcgcctat agtaagtggt gtaccagtgt
    31261 cattccctgg tactacacta caagttggtt cttctggaca gtatgttaga accatacaaa
    31321 atcagttaaa tgctatatct aattcttatc cagctgtacc aaaagttata gaagatggta
    31381 tctatggaac agatacagaa aacgctgtta agatattcca aggaatcttt ggtttacctc
    31441 aaagcggagt agtagatttt aaaacatggt atgaaatatc cagagtttat gtagctacaa
    31501 ctagaatagc ttctttaaat cctttaattt aaagcttgat ttagaacata aactcaaatt
    31561 attgaataaa attattaatt taaaataaaa atggctgtta tgaactaata tataccataa
    31621 gtattactta taagtattgt agtcttaaca gccatttttt agttataact tgttttttta
    31681 gaatcttaaa actttaaatg ggggatttta agcttcttaa aaacagtgct tagcaactta
    31741 gatttcttta aaatattata tttattttta agtttaataa aatgctattc taacgaaaaa
    31801 cctacttttt atttaaaatc tcacttatta tttaaaatgc tacttctcac ttagagtatt
    31861 actccttatt atttaaaaca ctatctatca cttagagtat tacttcttat tatttaaaac
    31921 actatccatc acttagaata ttacttctta tataaattat tatttattat aaatacaaat
    31981 aatattaatt taaaaagtta ttcctaattt aaataatact actatcttca tcagtgaacc
    32041 taaactgcaa ctttagactt attagctaaa gccaatatta gacctaaagc tatagatgca
    32101 aatgcagaag caattactct atactcagca gggaataaga atacaattgt atgacatggt
    32161 atccagaaaa atggtatagt ttttaaaaca ctaaaaccaa ggtaagcatt ccagtccaca
    32221 atatttacca catctttaag ttttacctta atcccctttc caacctcata ttttttatct
    32281 ataaaacagt ccataacctt atggaataaa aatacagttg gtgacattag tatattcata
    32341 gttgcactct taaatagagc atttgcaaaa gctattccct caaatggaag cataccatcc
    32401 acttgtgctt gacctacacc tgatgagtag attgacattc catatgtggt aactacacct
    32461 attattcccc aaactattgc tctataaaat actcctactg gtattttcca atccttatac
    32521 aaaattctag caccaagtaa atctcccatt gtagctaata cagcaaactt taaaaaacct
    32581 ccaatatatg gatgtgcacc tgttgcttcc ataaatactt ctctactact tggtattgct
    32641 aagacagcaa taatacaaat aagaactcca ctccatataa aatcgccttt tttcatattt
    32701 ataaatacta tttaatatat aaatagttct cctttctatt aaagatttat ttaatttaca
    32761 atctatctac aattatttat taatcactta ttattagata ttcattttcc atatttaaat
    32821 ttattctatc cctttatcta tttattttct tactactcta tccaccatta tctatatatt
    32881 tattttacga ttactctttc accctaaccc tttaattatc tattttttct gatattctta
    32941 tctaccatca tccatatatt tattttacga ttactctttc accctaaccc tttaattatc
    33001 tattttttct gatattctta tctaccatca tccatatatt tattttacga ttactctttc
    33061 accctaaccc tttaactatc tattttttct tactattctt atccacatca tccatatatt
    33121 tattttacga ttactctttc actctaaccc tttaactatc tattttttct gatattctta
    33181 tccaccatca cccatatatt tattttacaa ttactctttt accctaaccc tttaactatc
    33241 tatttttttc tggtattctt atctactatt atctgtatat ttattttatg attactcttt
    33301 taacctaccc cctatacttt atagtaatat gtttttaacc tttttcatta ttcccaatat
    33361 gctttataac tacaaatact ctcccccctt aaaaataata ataaaattaa tcaataaatt
    33421 tataatcata ttattactct atgtattaag caattactat gccaataaac tttgattttt
    33481 ttaaacaaat cttaaaaatc ctaaaatgct aattttcttt aacttttaat gaatctaata
    33541 gataacattt aattttcgtt atatttttca gaatatttct attattattt ttaagaaaaa
    33601 aaaataatgt taacatttct taacatacat taaaaaatgt taacattata aattgggttt
    33661 aatactttta ctttgactcg atttactttt attctacttc ttactttatt tttaacttag
    33721 actttatttt tttattactt atttgagtct tatttatttt attatcactc catatgttca
    33781 attacatttg tctaaattct ttgatacttt tattacataa ttttaacaag cttaagtgtt
    33841 atttgggtag tgcagttgat aattatttaa ataatcatca actgcatgtt tatatcatta
    33901 cagtagctta atgtatttaa tcatacttac ttaggatttt gaaatatctt agagattata
    33961 tttaacatta gtcaattgct gcataattgt aagcaattga aatttgagac ccatcttcat
    34021 tttctatagt gataggcttc ataattttta atccttcagt ttttatcttt tctaattctt
    34081 gttccatttt cttaattgtt tcctcaaggt ctttttgact tacatctttg actgcattag
    34141 ggtctttagc atagtctttt aattcttgaa tatgtttagc atactcttca taagtataat
    34201 gctcaacacc atacttttcc aattcagtag ggtcagttat tcctgatttt attagagatt
    34261 caagtttagg taaagcaata ttagatgaat catttccatt tgcaaatact gctccagttc
    34321 ctcctagtac cattgcagat accatcattg cacttataag ggattttttt attttcataa
    34381 ccaatcttcc tttcttagag atttatttgg gtagtgtagt ttgaaatgac tattgcaata
    34441 gttatcaacc acatccttag actatcacag tagtcatgtt tatgtcaagc ctttttaaaa
    34501 aacttttcaa taaaaaatac tatctcaaaa caaaattaat tattttgaga tagtatttta
    34561 attctaaatc ttttatatta ctaagattta tggttactct atccatgttc tatattgttc
    34621 tttattaact gctaacaaat tcccttttct tgatatgaca aagcgattat cattatagcc
    34681 actttgctca attgaaactt ctcctgaatc agtataaagt acatccttac cattactaga
    34741 tttatttaca tacgtttctt cgctattctc agaattagtt actttgctca tagatgattc
    34801 ttcatgctct ctaaattcaa ttacagatac ttttgccgta ctaaaatgag tctctccatc
    34861 acttttagct ttactaacaa gaatatcaga ttctactttg ggagaatata aatcagttga
    34921 tttactactt attgaaaatc caattttatc actttgttca ttttttgtta aaccaaaaga
    34981 ttcaacctca ttaatctctt tattttctgt tgcaaaaaca agacctgtcc cacaaactaa
    35041 tacagttgaa actaaaaaag taacataagt tgatttttta aatttcataa tattaactat
    35101 tctcttttct atttttgtct ttccaaatcc actacatatt gtcattgaaa atggattatt
    35161 ctcctctgct agacttatta gtgtggttgc ataatcagcc ctatattctt caccaagtat
    35221 actcataacc ttttcatcac aactaaattc tatgtcttta tttagtaaaa aaaacatcac
    35281 ccaaactaag ggattaaacc aatggacaac aagagctaca agcataaata actttaacag
    35341 attatcaaag ctattaatat gaaccatttc atgagttaaa acaaagtcta aagtttgatt
    35401 attagcataa ttcatttgct ttggcaaaat aattcgtggt tttaaaatac cagatgtaag
    35461 tggtgtccta gtaaattcag atatgcaaac aataaatctt ctaaaacggc tattcttaca
    35521 catccatttt ttaatgaact catgattttt tatatgaatt gaagttttaa aaagattaat
    35581 tattttaaaa tatctaaagc ataaaagtat gctaaacata atagtaacta taaaagacaa
    35641 aatgcccaac atttccaaca tcataatatt ttcaatatta gacattattt caaattcgtc
    35701 agaattgttt ttacctgtag agtcactagc tttcttaaga gtataatttt ctgttgatgt
    35761 attacccaat tccacatcaa aagtcgattc aattatacta taaatactaa aaccagaatt
    35821 taaacttact ggtattagaa gtttaaataa aacaatcaac cacaataata caaatacctt
    35881 tttaggtaat tttttaaata aacatgctct tataaaaata actattaaaa gtaatactcc
    35941 agaagtaaaa ctcatttcta acaatttaat gaacataaat cttacctcac tttaattttt
    36001 caacaatttg tttaagtttt gtaatctcat cacttgaaag attttcttta ttaataaaag
    36061 ctgaaagaaa tttttctgaa gaccctccaa acattttatt aattaaagtt tctgtttcct
    36121 gtttttgtac ttcctctttg cttattaaag ctttacaaac aaaattcggc tcaattctct
    36181 ctattgcacc ttttgacact aattttttta taacggtata cgtagtgttt ctattccatc
    36241 ctgtttcttc ttttaaaatt tttactaact ctccagcctt gctttctcct ctctcccata
    36301 gaacttccat tactttaagt tctgaatcaa ataattttat ctccatataa aatcgctcct
    36361 caaatatagt tatcacaata gtcattacta taataaaaaa ctatcatagt agtctatact
    36421 atgtcaatca tttatttttt aataataaaa actgtctttt taaaaaattc ttataaaaga
    36481 cagttttatc aatgttatac tttaatcttt aattaaagcc atattttatt taaatatata
    36541 actatatatc ttagtacata gtataagatt tttctttatc taatagtata tcctctacat
    36601 ctgggttttc ttttactaat tgtctataaa aattacaatt agtaacacct acatatggaa
    36661 ttagccatag tagacctatt ccaagagtag ctattgaaag tatataccat cctataaaac
    36721 taaagtttag tacaaataat ttaagtacat ttcctttcat catatctaaa ctagcaccca
    36781 ttgatttaaa tacacccata ttatccttgt cttcacaaat taagaaagta gcttgagaaa
    36841 catataatag caatatataa accggtaaca taagaacaag tattataaga actagagtta
    36901 ttccagtaga aataacagtc cctattccaa cattatcact tgataaatat tcaattgctc
    36961 cactagtaag taaaactcca aatgataaaa acgctcctat aattgtgatt ataaaagaat
    37021 aaatataaac aataattgat tcaaataaat aaaaaccaaa acttcttaaa taaattctcc
    37081 cacttacaaa gatatctcct atcttgactt tttcatcttt agtaattttc aagaacatac
    37141 atgtaaatcc tgctgaaacg caaaaagcta ttacagccac tacaatagta gtcaatggtt
    37201 caaaaggtaa tcctacaatt gatattaata ctatcaatgc aatatatact gccatagaaa
    37261 ttgcacatat cccccagttt ccagataact gagctttaga tactcgtttt aattcttgcc
    37321 ttgataccat aaaaaacacc cctttcattt tataaaaaaa cttttaaaaa tataaataat
    37381 cttttaacgt ataatattaa tatatcatat tttcgactat ataagataca attatt
//
LOCUS       DAJMZY010000031        37232 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.031, whole genome shotgun sequence.
ACCESSION   DAJMZY010000031 DAJMZY010000000
VERSION     DAJMZY010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 37232)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37232)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37232
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.031"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     regulatory      118..228
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            332..703
                     /locus_tag="OE968_001515"
     CDS             332..703
                     /locus_tag="OE968_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GrdX family protein"
                     /protein_id="HCP7218798.1"
                     /translation="MIIITNNPKVKEEVQGREVLFKDTTYIGILEASRDLIHEGYELL
                     SHPLYGSVKPNETPYRTVILKKGNRLDINSLTLIEEAIITASKFQNNKKTPKWTESVQ
                     DDFRVIDYDIFYNTIQRMQYE"
     gene            800..1747
                     /gene="trxB"
                     /locus_tag="OE968_001516"
     CDS             800..1747
                     /gene="trxB"
                     /locus_tag="OE968_001516"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HCP7218799.1"
                     /translation="MENVYDLVIIGSGPAGLAAGLYGARAKLKTLILEKDKTGGQIVI
                     THEIANYPGSVPNATGPSLIARMVEQCKEFGAEMLRDNIVDTELDGDIKVLKGEKAEY
                     RAKAVIIGTGATPRKIGCPGEKELTGKGVSYCATCDADFFEDFEVFVVGGGDSALEEA
                     MYLTKFARKVTIVHRRQGFRCAKSVEEKAKANPKIEFLLDTVIEEIKGDGILESVVFK
                     NKVTGETHEYFADEEDGTMGVFVFVGLDAQTDLFKGKVDMDEKGYIITDEDMRTNIPG
                     VFAAGDCRSKTLRQVVTATNDGAIASIVAEKYIDEKFGN"
     gene            1851..2168
                     /locus_tag="OE968_001517"
     CDS             1851..2168
                     /locus_tag="OE968_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol reductase thioredoxin"
                     /protein_id="HCP7218800.1"
                     /translation="MLDLDKATFEEEVLNAEGFVFVDFWSEGCEPCKALMPDVHKLAE
                     TYGDKIKFCKMDTTKARRLAIKQKVLGLPTMAIYKDGEKVDEVTKDDATVPNIENMIK
                     KYL"
     gene            2437..3723
                     /locus_tag="OE968_001518"
     CDS             2437..3723
                     /locus_tag="OE968_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006439082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine/sarcosine/betaine reductase component B
                     subunit"
                     /protein_id="HCP7218801.1"
                     /translation="MRLELGKIFIKDIQFGDVTEVKDGVLFINKQEMLQEIGGDEHIK
                     SIDIELARPGESVRITPVKDVIEPRVKVEGNGGIFPGIMSKVDTVGEGKTHALKGVAV
                     VTTGKIVGFQEGIIDMTGEGAKYTPFSKLNNVVVIAEPIDGLKQYAHEKAVRMIGFKA
                     AMYLGEVARNLTPDEVSVYETKPLLESIKEYPELPKVGYVYMLQTQGLLHDTYVYGVD
                     AKQIVPTLLYPTELMDGAIVSGNCVSACDKNPSYVHINNGVVEDLYARHGKDINFVGV
                     IITNENVYLADKERSSNWTSKLCKYLGLDAVIVSQEGFGNPDTDLIMNCKKIEMQGVK
                     TVIVTDEYAGRDGGSQSLADADVRADAVVTGGNANQVVVLPKLDKVIGHLEVVDVIAG
                     GSDGSLRADGTIEVEIQAITGATNETGFGHLTAKGY"
     gene            3835..4308
                     /locus_tag="OE968_001519"
     CDS             3835..4308
                     /locus_tag="OE968_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011986236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:3967..3969,aa:Sec)
                     /transl_table=11
                     /product="glycine/sarcosine/betaine reductase complex
                     selenoprotein A"
                     /protein_id="HCP7218802.1"
                     /translation="MSLLSNKKVLIIGDRDGIPGPAIEECVKTVEGAEVVFSSTECFV
                     UTAAGAMDLENQNRVKDAADKFGAENVVILLGAAEAEAAGLAAETVTAGDPTFAGPLA
                     GVALGLSVYHVVEEPIKSLFDESVYEDQISMMEMVLEVEEIEEEMSGIREEFCKF"
     gene            4340..5650
                     /gene="grdB"
                     /locus_tag="OE968_001520"
     CDS             4340..5650
                     /gene="grdB"
                     /locus_tag="OE968_001520"
                     /EC_number="1.21.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:5387..5389,aa:Sec)
                     /transl_table=11
                     /product="glycine reductase complex selenoprotein B"
                     /protein_id="HCP7218803.1"
                     /translation="MGKLKAVHYINQFFAGIGGEEKADTKPHVAETLPPISLQLDKLL
                     GEDIEIVGTVVCGDSYFNENIDSASEEVLSMVKGFEPQLFIAGPAFNAGRYGVAAGTI
                     TKVVKDALNIPALTGMYVENPGADMFKKDVYVVETSDSAAGMRKALPKIAKLAVKLAN
                     GEEIGTPKDEGYIARGIRVNYFHEDRGSKRAVDMLVKKIKGEPFETEYPMPNFDRVDP
                     SKAVKDLSKCKIALVTSGGIVPKGNPDRIESSSASKYGTYSIAGVMDLTEETYETAHG
                     GYDPVYANLDADRVLPVDVLRDLEKEGVIGKLHETFYTTVGNGTSVANSKKYASEIGA
                     ALVADGVDAVILTSTUGTCTRCGATMVKEIEKTGLPVVHMCTVVPISLTVGANRIVPT
                     IAIPHPLGNPALDPTEEKALRRGLVEKALNALTTEVDGQTVFEK"
     gene            5906..7438
                     /locus_tag="OE968_001521"
     CDS             5906..7438
                     /locus_tag="OE968_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014520415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III family protein"
                     /protein_id="HCP7218804.1"
                     /translation="MTYPVLKGAGYVLIHTPDMIVQNGSTCTVERATNPDSEFLKEVS
                     NHIRSYEDVVNYMPNQVYIGNRRPEELRDLPMPWCEQKIEGTRNGKFGEIMPQDEFIA
                     LMQISDAFDLVKLSQEFIDEVKPKIENNYPEIAPFVGKLKGDDIEEGKELVATHIAEG
                     LYHDGKFVGYVKRAHDVDVNLNAHTMFENLVVKASGVLSAIQMLRHSKIDPAEIDYVI
                     ECSEEACGDINQRGGGNFAKSIAEIAGLQNATGSDTRGFCAAPTHALIQAAALVKAGI
                     HKNVMVVAGGASAKLGMNAKDHVKKGLPVLEDVVGGFAVLVSENDGVNPVIRTDLTGK
                     HTVGTGSSPQAVMTALITSGLDRANLKITDVDVYSVEMQNPDITKPAGAGDVPEANYK
                     MIGALAVKRGDLEKKELKDFVSNKGLPGWAPTQGHIPSGAPYIGFLIDDLTTGNRNRA
                     MIVGKGSLFLGRMTNLFDGVSFIAERNTGVTEETSGISKDEIKKIIAESMKKLALDML
                     EE"
     gene            7449..8594
                     /locus_tag="OE968_001522"
     CDS             7449..8594
                     /locus_tag="OE968_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine reductase"
                     /protein_id="HCP7218805.1"
                     /translation="MSKKVIADVFLEVANAIESGEFGKKVKIGVTTLGSEHGVENMVN
                     GAQLAKSNLFDIVLIGPKVETDLEVVEVNDEKEMHAKMEELLDSGYIDACVTMHYNFP
                     IGVSTVGRVITPAKGKEMILATTTGTSATNRIEAMVRNAIYGIATAKSMGNKCPKVGI
                     LNVDGARQVEKCLKELKDNGYDMEFADSIRADGGCVMRGNDLLVGAPDVMVTDTLSGN
                     IFMKVFSSYTTGGDYEAQGFGYGPGVGEDYDRKVLIVSRASGSPVVANALKYAYDVVK
                     GDISNVARNEFAKVKKAKFDDIISSLTKKEVKAEKVEVKMPDKEIVTRQIAGVDIMDL
                     EDAVSELWKNGIYAESGMGCTGPIVLVNEAKGDLAVETLVKAGYTAK"
     gene            8904..9983
                     /locus_tag="OE968_001523"
     CDS             8904..9983
                     /locus_tag="OE968_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HCP7218806.1"
                     /translation="MSRVKNVVELLETKGVDALYLTKKTNVNYISGFPDEEAYAVICK
                     DGNFLVTDSRYMELAEKVCKDFEIINWHNFDRSVAKAVKSVCDKVGIKKLGFERTNIV
                     FDKYEELKNLIEKDNGELIPTENIVETLRYVKDKDEIKNTRKACEIADKALEELIPHI
                     KAGVSEIELATRLEYFMKMNGAQNIGFETILISGAKTSLLHGKPSDKIIEKGDFVLID
                     YGAMYNGYISDTTRTFIVGGASEKQLEIYNLVKEAQNVGVENMKAGVHATIPDAEIRK
                     VVKKYEDYYYQGIGHGVGRDVHEEPFIGNYGDKIIEEGCIITMEPGIYFPGWGGVRIE
                     DTVLITKNGPERLTKFPKDLMILDK"
     gene            10096..10695
                     /locus_tag="OE968_001524"
     CDS             10096..10695
                     /locus_tag="OE968_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218807.1"
                     /translation="MYKKHKFIKNIKKAWYKIKLIDRCLIIVMAILMFQSIYNLFVNE
                     VNSQDTTTIDVVVRTTSAAIFGYFLSANFIKRPLRKYTNTDVSSNLFIDNNLSPKGQE
                     SNQNNIMNVKNTIGFTSEADNYEKKIPINNNEGFEEGETSELQIIIATVICIVALTVL
                     FVVRNFTTTTSASLGTISQMRDFVSGCVGFLLGCPSKPD"
     gene            complement(10882..11754)
                     /locus_tag="OE968_001525"
     CDS             complement(10882..11754)
                     /locus_tag="OE968_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCP7218808.1"
                     /translation="MNINYLYYFQTVCKYKNMTKAAESIHISQPSITLAIKELEKELG
                     FELFYRIGNKIELTPEGKIFLDKSKHFIKQFEDFQCDALDLGKKRKASLKIGIPTVLG
                     TFLLSKILPRFNVIYPDIELKIFEVPTFVGAKMIEESTLDFCIGIIDSDIYDDIDSKT
                     IYKTELYLVTNPKNELAKHPIISNYMLKNVPFVILSEGSYHYKIITKRLEKAKPNIIL
                     HSNQLSTIRYLLENDLASTILYKEIFQNTENLCSIPLERAITANIGVLWRRNQYISHS
                     MKLFIEYMASIHIN"
     gene            12171..13574
                     /locus_tag="OE968_001526"
     CDS             12171..13574
                     /locus_tag="OE968_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218809.1"
                     /translation="MKGSDLVKFELMDFLMNPFVLMFAAVITGILFGKIKFGKFNFGV
                     SGALFTGLFIGWLAYSLGNLIIAKGETAAGYKAATVMMGNGIISSDFFDFFLIIFVAA
                     VGLLAAKDMKAVLKKYGARFVILGVLITFIGGSMTYAMTLLSSDKGSSAYEVSGVYTG
                     ALTSSPGLAAALETAGKHAEDVSKEFEKASIKDKKEILKVVDPEGKLDVNTTTSLTQE
                     QIDKYIAYAEAGVGIGHAVAYPFGVLIVILGVNFLPKLFRMDLKEERRKYEKEMKEAR
                     DSVSGKTIPEVPFNIITFFLTCLAGYLVGGIHVFMGPLGYFTLGATGGSLIVSLVLGY
                     IGKIGVVNFRMEEKVLNILKQIGLVFFLAIVGLRYGGKVVDSIMTSGMHLALVAIAVG
                     VTAMMIGFLVGKYVFKLNWILLSGAVCGGMTSTPGLGAAVDALDSDDPAAGYGATYPF
                     ALLTKVILVIVLHKLPM"
     gene            13601..15145
                     /locus_tag="OE968_001527"
     CDS             13601..15145
                     /locus_tag="OE968_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA hydrolase/transferase family protein"
                     /protein_id="HCP7218810.1"
                     /translation="MNNEGAFEELSGRLRNKELCDLIMNADEAAKIIEDGMVIGVSGF
                     TPSGYPKAVPLAVSERAKSGEKIKLTVYSGASLGPEVDGAWSEAGIIERRLPYQTNSI
                     LRNNINKGVVDYIDMHLSHSTQFLNYGTIPKVDVAIVEALAITEEGNIIPTSGIGNSP
                     SFIKSADKVIVEINLAKPMEMEGMADIYITENPPNRKPIEINHPKDRIGTTYIPCGLD
                     KIAGVVITNMQDKTRPLGVVDEASKKISNNIIAFLREEVKSGRLSKNLLPLQSGVGSV
                     ANAVLYGLCESEFENLTCYTEVVQDSMLDLIRMGKVTMASTTSVSPSPEGLIKFEKDI
                     DFFKDKIILRPQEISNNPEIARRIGVIAMNTAIEVDIYGNVNSTHIMGSKMMNGIGGS
                     GDFARNGAITIFSTESIAKNGDISSIVPMVSHVDHTEHDVMVIVTEQGYADLRGLAPR
                     ERAIKIIENCAHPDYKEQLRDYLNRACKSGAKQTPHILDEALSWHSKFMSTGTMKKAE
                     TFKSAL"
     gene            15176..16567
                     /locus_tag="OE968_001528"
     CDS             15176..16567
                     /locus_tag="OE968_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase family protein"
                     /protein_id="HCP7218811.1"
                     /translation="MEKAVENFEDLSKEYINGYIERARKAQREFECYTQEQVDKIVKI
                     VGKVVYYNAEYLAKLAVEETGMGVYEDKVAKNKSKAKVIYNNLKDKKSVGIIDIDRET
                     GITKVAKPVGVVAAITPCTNPIVTPMSNAMFALKGRNAIIITPHHKAIGCSTKTVEMI
                     NEELEKIGAPENLIQILDQQSRENTRNLISSADVVIATGGMGMVKAAYSSGKPALGVG
                     AGNVQCIIDRDVDIKEAVPKIIAGRIFDNGIICSGEQSVIVAEEMFDKIMDEFKNNKG
                     FIVRDKVQKEAFRNAMFVNKSMNKDAVGQSVHTIAKIAGVEIPEDTKIIVIEADGPGE
                     EDIIAKEKMCPVISAYKYKSFEEGVAIAKANLNVEGKGHSVSIHSNTVKNIEYAGENI
                     EVSRFVINQCCATSAGGSFFNGLAPTNTLGCGSWGNNSISENLDYKHLINISRIAYYM
                     PENEVPTDEELWG"
     gene            16760..18256
                     /gene="abfD"
                     /locus_tag="OE968_001529"
     CDS             16760..18256
                     /gene="abfD"
                     /locus_tag="OE968_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxybutyryl-CoA
                     dehydratase/vinylacetyl-CoA-Delta-isomerase"
                     /protein_id="HCP7218812.1"
                     /translation="MALMTGAQYIESLRKLNTKVYMFGEEVKNWVDHPMIRPSINCVA
                     ATYDLAHDPEYADLMTVTSNITGEKINRFGHLHQSVDDLIKKVKMQRLCGQKTASCFQ
                     RCVGMDAFNAVYSTTFECDKAHGTNYHDNFVKYLTYIQENDLVVDGAMTDPKGDRSLS
                     PSAQPDPDMFLHIVERREDGIIVRGAKAHQTGSINSHEHLIMPTISMTEADKDYAVSF
                     AVPSDAEGVFMIYGRQSCDTRKLEEGADVDLGNKEFGGQEALVVFDNVFVPNDRIFLC
                     GEWDFSGMLVERFAGYHRQSYGGCKVGVGDVIIGAAALAADYNGANKASHIKDKLIEM
                     THLNESLYCCGIACSSEGHKTEAGNYQIDLLLANVCKQNVTRFPYEIVRLAEDIAGGL
                     MVTMPSEKDFKSDLKVGTSGMTIGEVCNKYFKASSVASTEERMRILRFLENICLGSSA
                     VGYRTESMHGAGSPQAQRIMISRQGNINQKKELAKKIAGIKKEEALNL"
     gene            18391..18666
                     /locus_tag="OE968_001530"
     CDS             18391..18666
                     /locus_tag="OE968_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218813.1"
                     /translation="MTCGVRFCGGCNPRYERGKALTIIKEHFNGRVDFSIAQENVEYD
                     LLLIIGGCATLCASYQQYKVKNECVKMWDFSHIERVINVIESAICET"
     gene            18690..19997
                     /locus_tag="OE968_001531"
     CDS             18690..19997
                     /locus_tag="OE968_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA hydrolase/transferase family protein"
                     /protein_id="HCP7218814.1"
                     /translation="MSWQELYQSKLCSATEAVKQIKNGDTVVFAHCVGEPPALVEAMI
                     ENAEQYKDVEIKHMVSLGSGGYTAKGMEAHFRVNPMFVSGNVRKAIENGDGDFTPAFF
                     HEVPKLLREKRLKCDVVLAQVTPPDEHGYCSLGTSVDYTYEAIKTARTVIVQVNDQFP
                     RTYGEVVHVSEFDYIVEKSQPLFELQPAKIGEVEEAIGKNCASLIEDGSTLQLGIGGI
                     PDAVMLFLTDKKDLGIHSEMISDGTLALYEKGVINGKYKNFDKEKMTVTFLMGTKKLY
                     DFANNNPAVEVKPVDYVNHPAIIMKQHKMVSINSAIQVDLMGQVVAEAMGLRQFSGVG
                     GQVDFIRGVSMGEDGKAIIAMPSITTKKDGTVISKIVSIVDEGAPITTSRNDVDYIVT
                     EYGIAELKGKSLRERARNLINIAHPSVRESLAVEFEKRFKEKY"
     gene            20017..21135
                     /locus_tag="OE968_001532"
     CDS             20017..21135
                     /locus_tag="OE968_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxybutyrate dehydrogenase"
                     /protein_id="HCP7218815.1"
                     /translation="MEALRVVPKIFYFDTFKEFNEEFKIGKNDLVITNEFIYEPYMKP
                     LGIDTNLIFQEKFGTGEPSDEMIDSMTKEMKKYNFDRIIAFGGGTIVDICKILALDVP
                     EKSIDLFEGEVSPKKVKELVVVPTTCGTGSEVTNVAIAELKSKHTKKGLAVEETYADY
                     AVLIPETVKGLPYKFFVTSSVDALIHAIESYLSPKASPFTEMYSLQAIKMIMDGYKKI
                     VDKGEEERFNHLRDFVLASNYAGIAFGNAGCAAVHALSYSIGGAFHVAHGEANYQFFT
                     EVFKMYSRKKPNGKIIKCTKILADALECDPNCDVYGELEKFLNKLIAKKALREYGMVE
                     SQIDEFTDSTIANQQRLLANNYVELSREEIREIFANLY"
     gene            21422..22342
                     /locus_tag="OE968_001533"
     CDS             21422..22342
                     /locus_tag="OE968_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     family protein"
                     /protein_id="HCP7218816.1"
                     /translation="MYKSENFSKKSVLINSFLSKFLKIIGWGLVSLFTLSALVLSTIS
                     IIIGWAVILPIQVCAVFLLIGGVCIFKGKRLGDQISRYKKYCTIINNRNIIPVELIAE
                     NTSKSLNFIIKDVQKMIDKNYFINTYIDKRNNQIVLTNEDFVPPRYEDVAYEVKEEEK
                     TDESNEVDTIINKGMNYLTQIKEANKNIKSESMGDKIVQVEDVTSKIFDVVKHDPSKL
                     TQIQKFMDYYLPTTLKLLNSYHTLEEQGIDRENITTTMESIENTMNTIVVAFENQLDY
                     LFEDEAIDISTDITVLENMLVQEGLTSGKF"
     gene            22457..23614
                     /locus_tag="OE968_001534"
     CDS             22457..23614
                     /locus_tag="OE968_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HCP7218817.1"
                     /translation="MNNLDDIPVMPTLTLDPFGEESNTNDIDNSDLLMKKDEKDPEEE
                     KLSESERKMVKEFAEKIDITNTNMILQYGAGAQKKVASFSETALKSVKTRDLGEVGDM
                     LTNLVTDLKAFSADEKEQSGFLGIFKKANNKISNLKTKYDSAEVNVDKVSKELQKHQV
                     KILKDIAMLDKMYELNLAYSKELTMYIIAGKQKLKDMKEYEMPKLREKARLSGSTEDA
                     QSVNDMVSLCDRFEKKIHDLELTRMVSLQMAPQIRLVQNSNNLMAEKIQSTIVNTIPL
                     WKNQIVLALGISHLNQAMKAQREVSNMTNELLLKNAETLKMGTIETAKESERGIVDID
                     TIKKTNQSLISTIDEVVKIQHDGRIKRQEAEVELSKIENELKSKLLEFTVK"
     gene            complement(23695..24591)
                     /locus_tag="OE968_001535"
     CDS             complement(23695..24591)
                     /locus_tag="OE968_001535"
                     /inference="COORDINATES: protein motif:HMM:NF033516.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HCP7218818.1"
                     /translation="MLKKVKYPIGQVKVSDKFKTIKLLSRKYSISSMCKLISVSRSGY
                     YKWLSYSKKSSDRGIKDRIIKDYIIEIHKKYRGTYGRKRICTYLNKILDTPINHKRVY
                     RLMKELGIKSIIRKKVYRRKFKSYEIYDNILNREFRANQPLEKICMDITYIPIGKKFL
                     YMNVAKDLFNGEIVAYEISTKMDTKLVNNTVNQLINMNLAKDCILHTDQGSQYTSRSY
                     SKRLKDNGIIQSMSRRGNCWDNAPIESFFSHFKSELIYLIDTTDPKEMISLINDYIYF
                     YNNERIQLKNGMSPIEYRTHSE"
     gene            complement(24549..24866)
                     /locus_tag="OE968_001536"
     CDS             complement(24549..24866)
                     /locus_tag="OE968_001536"
                     /inference="COORDINATES: protein motif:HMM:NF013677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCP7218819.1"
                     /translation="MSKKHKKYSKELKLKAVNLYIKEGYSSYKIAEMLNIRSKTQVQN
                     WVKDYKNKGKTAFDDETRGRFKNISLENDNRKFKSVEEELKYLRMENEFLKKLSTLLD
                     KSK"
     gene            complement(25003..26502)
                     /locus_tag="OE968_001537"
     CDS             complement(25003..26502)
                     /locus_tag="OE968_001537"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HCP7218820.1"
                     /translation="MAFYFDTPSHTFSEYLLVPGFSSTDCIPANVSLKTPVTKFKKGE
                     EADIYMNIPLTSAIMQSVSDDKMAIALAKEGGISFIYGFQTIEDEAAMVARVKSHKAG
                     FVVSDSNIKPDNTLKDILDLKEKTGHSTVAVTEDGTSTGKLLGIVASRDYRISRMDLD
                     TKVSEFMTPMSSIVYANKDVTLKEANNIIWDHKLNSLPVLDDNGNLMYMVFRKDYSSH
                     KENPLELLDSSKRYVVGAGINTRDFAERVPALVEAGADVLCIDSSEGFSEWQKITLDF
                     IREKYGDTVKVGAGNVVDREGFLYLAEAGADFVKVGIGGGSICITREQKGIGRGQATS
                     IIEVAQARDEYFEKTGIYIPICSDGGIVYDHHITLALAMGADFIMLGRYFSRFDESPT
                     NKVNINGSYMKEYWGEGSARARNWQRYDLGGDKKLSFEEGVDSYVPYAGSLKDNVTLS
                     LSKVRSTMCNCGALSIPELQKNAKLTLVSSTSIVEGGAHDVMLKDNRNL"
     gene            27098..28522
                     /locus_tag="OE968_001538"
     CDS             27098..28522
                     /locus_tag="OE968_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICB"
                     /protein_id="HCP7218821.1"
                     /translation="MSSSNQSTIKTSIQRVGKFLSGMVMPNIGAFIAWGLITALFIPT
                     GWMPNEKLSTIGDPMIKYLLPLLIAYTGGKAIAGQRGGVIGAAAAMGVIVGADIPMFI
                     GAMIMGPFAGWVIKKFDKFVDGKIPTGFEMLVNNFSIGIIGMLLAILGFYAIGPAIVA
                     GTALIESGVQFIVSKSLLPLVSVFIEPGKVLFLNNAINHGILGPIGIAEAKEAGKSIM
                     FLLESNPGPGLGVLLAYWMFSRGSVKQSAPGAVIIHFFGGIHEIYFPYILMNPVLILA
                     TMAGGAAGILTFSILGAGLVAAPSPGSIFALMALAPKGGLLPVLAGVAVATVVSFLVA
                     APFVKRASANESEEDSTSLEEAKAKMSDMKSASKNSEKNIEKKQLEVNEIKKIVFACD
                     AGMGSSAMGASRFKNRIKNLDLDIEITNSSVDNLPDDTQIVVTHNTLVERVAKNNSSV
                     EIVSINNFLNDPNLDTLFKRLESK"
     gene            28557..30686
                     /locus_tag="OE968_001539"
     CDS             28557..30686
                     /locus_tag="OE968_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HCP7218822.1"
                     /translation="MKKKKITSRQKKIILMIVENSKKNIPITISEIAGTLELSSRTVL
                     RDMSGIEKWFDENDFNFVKKPGVGLILEENIENQNFIIELLEEEKIEKEYSKEERNLI
                     ILSKLLVSNEPVKSYYFAKILKVSEGVLNNDFSLASKWLERFDIELVRKPGLGVYLKG
                     QEKSFREAYVNLIYDSFNEKEILDMVRNISENIQTDKAIEILSENRLLNLMDRCIIIK
                     VEATLTKKLSDLDVNLADSAYIGLVVHISLALQRIKNGENITMDKEFLKELSITEEFK
                     LAKEIVKGMETDFNMDIPVDEVGYITMHIRGAKQRSSSNHKALNLDDIEIMEITNKMI
                     DLAEDEFKISLKNDERLFKDLANHLGPSINRLNMGLEIRNPLLDEIKSKYSYAYDGVE
                     KISRIIKDKLNINSIPESEIGYIAMHFASAIEKNLMMNTNINIVVACPTGIGTSRFLS
                     TKIENKFPNLNILETISAINIDEEYLKGKDVDLIVSTVELNTSLNYICVGPFMSLDDE
                     QIIKEKIKSIAQNKLINLNTKNDTKSKNKVYEQITESMNIGKDILQFLEEIRFEKFES
                     KDLSELIEDSSKIFAKSSEDIMSIKESLKERLKISIPYIEESKILLLHCMSERIDIMK
                     LSIIKLENRIVLDSNEEIDNVVFMLLPKNSPSYQRQIMSEISGSLIDNIIFTNKINKF
                     SIEEMTLEVKDIVFNFYTNRLKAFIDE"
     gene            30716..31138
                     /locus_tag="OE968_001540"
     CDS             30716..31138
                     /locus_tag="OE968_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HCP7218823.1"
                     /translation="MSKVLNENNIFLGLDSVSKEEAITLAGRKLVENGYVKEEYIPAM
                     LEREKVMTTYMGMGVAIPHGVNEAKKEILSSGIVILQFPNGIDFDGEKAYLLIGIAGV
                     GDEHLEILSNIAVVLDDDLTERLKNSNDKQAFMEAFAK"
     gene            31157..32308
                     /locus_tag="OE968_001541"
     CDS             31157..32308
                     /locus_tag="OE968_001541"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HCP7218824.1"
                     /translation="MKKAIQFGAGNIGRGFIGGLLVKSGYHVVFADVNEEILNSINKD
                     KKYTIHIRDVECIDEVIDNISAVSSIKEEIIDEIVQAEIITTAVGPLVLTKIASTIAK
                     GIKARKEKGLTSNLNIIACENAIYASSSLKEEVLKYLNKEEVEYLEIYVGFPNCSVDR
                     IVPPGKNENPLDVTVENFYEWNVEKQGFKGEIPTIVGMNLADNLMAYIERKLFTLNTG
                     HAITAYIGYLKGYKTIEESIKDKFICDIVKSAMVESGEGLIKKYNFDSEAHYKYIDKI
                     LNRFKNPYLNDDVLRVGREPLRKLSDKDRLIKPLMTAKSYGLSVDNLILGIGAALHYN
                     NSEDTQSVELQELIKSNGVKKAVAKIANISNDEELLNNIEKSYIFMKNL"
     regulatory      32414..32515
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            32698..33270
                     /locus_tag="OE968_001542"
     CDS             32698..33270
                     /locus_tag="OE968_001542"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HCP7218825.1"
                     /translation="MKALQEKILREGSVSGNDILKVDSFLNHQIDVAFLNEIGREFKE
                     RFKEEKVDKIFTIEASGIAIASIVSQYFDNAPVVFAKKSESKNLDKDVYETNVYSFTK
                     AREYSVKVSKKYINKGENILIVDDFLANGRAALGLKDLIEQAEANLVGVGIVIEKGFQ
                     AGGALLKANDVRLESLAVVESIDNGTVKFR"
     gene            33334..33984
                     /gene="fsa"
                     /locus_tag="OE968_001543"
     CDS             33334..33984
                     /gene="fsa"
                     /locus_tag="OE968_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HCP7218826.1"
                     /translation="MIFFIDTANIEEIKEANDLGVICGVTTNPSLIAKEGRDFIEVVK
                     EISEIVDGPISAEVISLEHEGMIEEAEKLSKIHKNIVIKIPMTAEGLKAVKVLSSKGI
                     KTNVTLIFSAGQALLAARAGATYVSPFVGRLDDISQNGLDLIEEIVDIFSVNSIEAQI
                     IVASVRNPIHVLQAARMGADIATVPLKVINQMIKHPLTDKGIDSFMKDWEGASLKL"
     gene            34136..37060
                     /locus_tag="OE968_001544"
     CDS             34136..37060
                     /locus_tag="OE968_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HCP7218827.1"
                     /translation="MDKILREIQREDKKNPYTDQELAEMLNVARSEVISVRKKNNILD
                     SRERRKKILIKDISKIVSENPQMSERKITEILIENGYNISRSAVSKLLKEENLNQSKI
                     GIKDKEPASSGKYVKVSKVVEEDGFEELIGIKGSLKEKVNLAKSAIMYPPNGLHTIIY
                     GETGVGKSELATCMYKYAIKNNIKEENSPFIVFNCADYAENPNLLIAQLFGVVKGAYT
                     GADANREGLVEQANNGILFLDEIHRLPAAGQEILFSLIDRGEFRRLGESSSNRKANVL
                     IISATTENPDSNLLQTFRRRIPMVINLPNMSERPKSERYEIIIKFFEREAKRVNKNFI
                     ITKEVMCALMNYKCTGNIGQLKSDIQVTCARAFSKSIFSSDKVIIDLDSLRDYIKSGY
                     YDCNCKNEKYSEFSVEDIYIDISELVSGKNRILSDNEISEIYNYAEKELKVLESKCFS
                     EEELKNAFIEKLDKKFNAIKNNKNLSDRRSRIDWGGQLKESTLEIMDKVIVFIKEQFK
                     HVNQGLYLALAIHIEHAIGRIKDGKTIINPSLDKIKASMPMEYELSRYIMGIVEDLTQ
                     VTFPEDELGYLAYYINKFCYNEESIKDKVKVVIVTHGKVGIEMSKVVNHILGIECTLG
                     IEIALTDSPSEGIEHVLEELQKIEARKGILVLIDMGSLVILGDEVEKRLGIRCKTVNR
                     VDTLLAMEAGKLATIEGKSLDGIIADLKKNKNYAMINTNKFSYRKNEYGKKNVIITLC
                     LSGVGTALNLKEHIEKQIKEYDTLIEVKPVAFLNNNLEEELNDIEAEYNIIAICGTID
                     IDYKNVPFISYNEVLGKNGINKVLEHLNSKQPVLNIENQLNNLIHEDLILYNFEGISK
                     EYIIDTLVSKLEEGGYVDSKYILSVYKREAMGSVVMASKVAVPHGLPENVIKPAIAIA
                     RLNKPIVWDNKFMVDLVVLLALKENNKKEIRSLFSKINDQHTLEVLLNTEDKNEIKEL
                     LS"
BASE COUNT        14567 a         4191 c         6929 g        11545 t
ORIGIN      
        1 tgcaaatttt atagaatgtt tatatactta agtcaacaga gatagaaaaa agctatttat
       61 agaaaacaaa ggataaattg cttaatttta aattttctga aaaaaataat aatccggatg
      121 aagagtatgg gagactgctt tataaaaagc gaccgaaggg acaagtttaa tcttacttac
      181 ccaaaagatt agatgaaatt ctcaggtaaa ggtgactgta cttggacggg gctctgaaaa
      241 tgattttaac agggaagaca aattgggaga tttgtttttc ctgtttttta tttatcaagt
      301 aataaataaa agtttgaaag agagtaaaaa aatgataata attacgaata atccaaaagt
      361 aaaagaagaa gttcaaggca gagaagtttt gtttaaagac acaacttata ttggaatctt
      421 agaagcaagt agagatttga tacatgaagg ttatgaactt ttatctcatc cactctatgg
      481 gagtgtaaag ccaaatgaaa caccttacag gactgttata ctaaagaaag gaaatcgttt
      541 ggatataaac tctttaacct taattgaaga agcaatcatc actgcaagta aatttcagaa
      601 taataaaaag actccaaaat ggacagaaag tgttcaagat gattttagag taattgatta
      661 tgatatattt tataatacaa tacaaagaat gcagtatgaa taaaaaaaaa ttgttaaaaa
      721 gttattaaaa cagcctaaat attaaatcta atttaatatt aaataaaatg agaaatttaa
      781 ttggggagga taagtcaaaa tggaaaatgt gtatgactta gtaataattg gttcaggacc
      841 agcagggctt gcagcaggtc tttatggagc aagagcaaag ttaaaaactc taatcctaga
      901 aaaagacaag actggtggac aaattgtaat aacacatgaa attgcaaatt atccagggtc
      961 agttccaaat gcaacaggac caagtttaat agctagaatg gttgaacagt gtaaagagtt
     1021 tggagcagaa atgctaagag acaacattgt tgatactgag ctagatggag atataaaagt
     1081 tttaaaaggg gaaaaggcag aatatagagc aaaagcagta ataataggaa caggagcaac
     1141 accaagaaag attggttgtc ctggagaaaa agaacttact ggtaaagggg tttcatattg
     1201 tgcaacttgt gatgcagatt tctttgaaga ttttgaagta tttgttgtag gtggaggaga
     1261 cagtgcatta gaagaagcaa tgtatttaac taaatttgct agaaaagtaa caattgtaca
     1321 tagaagacaa ggatttagat gtgctaagag tgttgaagaa aaagcaaaag ctaatccaaa
     1381 gatagagttt ttattagata cagtaattga agaaatcaaa ggtgatggaa tattagaatc
     1441 agttgtattt aaaaataaag ttactggaga aactcatgaa tactttgcag atgaagaaga
     1501 tggaacaatg ggagtatttg tgttcgttgg attagatgct caaactgatt tattcaaagg
     1561 taaagttgat atggatgaaa aaggttacat aataactgat gaagatatga gaactaacat
     1621 accaggcgta tttgcagcag gagattgtag atctaagact ctaagacagg ttgtaactgc
     1681 aactaatgat ggagcaattg catctatagt agctgagaaa tacattgatg aaaaatttgg
     1741 gaactagaat ctgtaaatta agaaatagtg tctgtaaatt taatgaataa tatttaaaat
     1801 taaaattaat atttaaaatt aaaataaaaa tttcaagggg gaataagaaa atgttagatt
     1861 tagataaggc tacatttgaa gaagaagttt taaatgcaga aggttttgta tttgttgatt
     1921 tttggagtga aggttgtgag ccttgtaaag ctttaatgcc agatgttcat aaattagctg
     1981 agacttatgg ggataaaata aaattctgta agatggatac aacaaaagct agaagattag
     2041 ctataaaaca aaaagtatta ggtcttccaa ctatggctat atacaaagat ggagaaaaag
     2101 tagacgaagt tactaaggat gatgctacag ttcctaatat agaaaacatg attaaaaaat
     2161 atctttaata tgttgataaa ttattaacat taaaagaaaa aatctatttt tatctgaaga
     2221 taagaagaaa aaggttttta tgtccaactt tgttaaaaaa ataattttaa ataaaataat
     2281 ttttttacaa taaatatttt ttagtaataa aataaagatt taaggcataa aaacacaata
     2341 atatatcttt aaaaaaataa gataaattgt aaaatgatat aattttgaga aaaactcaaa
     2401 tgcatataca caaattaaat aacaggaggt gcaagtatgc gtcttgaatt agggaaaatc
     2461 tttataaaag atattcaatt tggtgatgta acagaagtaa aagatggagt attattcatc
     2521 aataagcaag agatgctaca agaaattggt ggagatgagc atattaaatc tatagatata
     2581 gaattagctc gtccaggtga aagcgtaaga ataacacctg taaaagatgt tattgagcca
     2641 agagtaaaag ttgaaggtaa tgggggaatc ttccctggta tcatgtctaa agttgacact
     2701 gtaggagaag gaaaaactca tgctttaaaa ggtgtagctg ttgtaactac tggaaaaata
     2761 gtaggtttcc aagaaggtat aatagacatg actggagaag gagctaagta cactccattt
     2821 tctaaattaa ataatgtagt agtaatagct gaacctattg atggtttaaa acaatacgct
     2881 catgaaaaag ctgttagaat gataggattc aaagcagcaa tgtacttagg agaagtagca
     2941 agaaatctta ctccagatga agtttcagta tatgaaacta aacctcttct tgaatcaata
     3001 aaagaatatc cagagcttcc aaaagtagga tatgtttaca tgcttcagac tcaaggttta
     3061 ttacatgata cttatgtata tggagtagat gcaaaacaaa tagtaccaac tttattatat
     3121 ccaacagaat taatggacgg agcaattgta agtggtaact gtgtttctgc atgtgacaaa
     3181 aacccaagtt atgttcatat aaacaatggg gttgttgaag acttatatgc aagacatggt
     3241 aaagatataa actttgtagg tgtaattata actaatgaaa atgtttatct agcagataaa
     3301 gaaagatctt caaactggac ttctaaatta tgtaaatatt taggattaga tgcagttata
     3361 gtttcacaag aaggttttgg aaatcctgat actgacctta taatgaactg taagaagata
     3421 gaaatgcaag gtgttaaaac agttatagtt acagatgaat atgctggacg tgatggaggt
     3481 tctcaatcac ttgcagatgc agatgtaaga gctgatgctg ttgtaacagg tggaaatgcc
     3541 aaccaagttg tagttcttcc taagttagat aaagttattg gacatttaga agtagtagat
     3601 gtaatagctg gtggttctga tggaagttta agagctgatg gaactattga agttgaaatc
     3661 caagctataa caggtgcaac taatgaaaca ggatttggtc atttaactgc taaaggatat
     3721 taagaagtat tttattaaac gattgagtaa tgttaataaa acatattata gataattata
     3781 ataagtgtta tagatatata aaaatatatt agaaatataa taaggaggat tattatgagt
     3841 ttacttagta ataaaaaggt tcttataata ggtgaccgtg atggtatacc aggacctgcg
     3901 atagaagaat gtgtaaaaac agtagaagga gcagaggttg ttttctcatc tacagaatgc
     3961 tttgtctgaa cagctgctgg ggctatggac ttagaaaatc aaaacagagt taaagatgct
     4021 gctgataaat tcggagctga aaatgttgtg attttactag gtgctgctga agccgaagct
     4081 gcaggtcttg cagccgaaac agtaactgct ggagatccaa ctttcgctgg accacttgct
     4141 ggagttgcct taggattaag tgtttaccac gttgttgagg aaccaataaa atcattattt
     4201 gatgaaagtg tatatgaaga ccaaataagt atgatggaaa tggttttaga agttgaagaa
     4261 atagaagaag aaatgtctgg tataagagaa gaattttgta aattttaatg cctaaaagca
     4321 aaaggggtga aactaagaga tgggaaaact aaaagcagta cattatatta atcagttctt
     4381 tgctggtata ggtggagaag aaaaagctga tactaagcca catgtggcag aaactttacc
     4441 tccaataagt ttacaacttg ataaattatt aggtgaagat attgaaatag ttggaacagt
     4501 agtttgtgga gatagctatt tcaatgaaaa tatagatagt gcaagtgaag aagttttatc
     4561 aatggtaaaa ggttttgaac cacaactttt catagctggt cctgcattta atgctggtag
     4621 atatggggtt gctgctggaa caataactaa agttgtaaaa gatgctttga atataccagc
     4681 tttaacaggt atgtatgttg aaaatccagg agcagatatg ttcaaaaagg atgtttatgt
     4741 agtagaaact tctgattctg cagcaggtat gagaaaggca cttcctaaga tagctaaact
     4801 tgcagtaaaa cttgctaatg gagaagaaat tggaactcct aaagatgaag gatacatagc
     4861 tagaggaata agagttaact acttccatga agacagaggt tctaagagag ctgttgacat
     4921 gttagttaag aaaataaaag gtgaaccatt tgaaactgaa tacccaatgc caaactttga
     4981 tagagttgac ccaagtaaag ctgtaaaaga tttatcaaaa tgtaaaatag ctttagttac
     5041 ttctggtggt atagttccaa aaggaaatcc agatagaata gagtcttctt cagcttctaa
     5101 atatggaact tattctatag caggagttat ggatttaaca gaagagactt atgaaactgc
     5161 acatggtgga tatgacccag tgtatgcaaa tttagatgca gatagagtat tacctgttga
     5221 tgttcttaga gatttagaaa aagaaggtgt aattggaaaa ttacatgaga ctttctatac
     5281 aactgtaggt aatggtacat ctgttgcaaa ctctaaaaaa tatgcttctg aaattggagc
     5341 agcattagtg gctgatggtg tagatgcagt aatattaact tctacatgag gtacttgtac
     5401 tcgttgcggt gcaacgatgg taaaagaaat agaaaaaact ggacttccag tagttcatat
     5461 gtgtacagta gtacctattt cattaacagt aggggctaat agaatagttc caactatagc
     5521 aatacctcat ccacttggaa atccagcgct tgaccctaca gaagaaaaag ccctaagaag
     5581 aggccttgta gaaaaagcat taaatgcttt aactacagaa gtagatggtc aaacagtatt
     5641 tgaaaaataa aaataacaca cacatatatt atatagataa aaatataaac acacactaaa
     5701 aataaaaaat aactatacac aaaaaaataa tatagatttc atgaatggat aaattggagt
     5761 tattcattca tgaaatctta aaaaatgcca aaatacataa acaataatag aatcaaatat
     5821 acaataaaat acaatgatta gagcttttaa taagtttaat aagattaaaa aataagtgtt
     5881 cataaaattt atggaggtgc acaaaatgac ttatccagtt ttaaaagggg caggctatgt
     5941 acttattcat actccagata tgatagtgca aaatggaagt acttgtacag ttgaaagagc
     6001 aacaaatcca gattcagaat ttttaaaaga agtaagtaat catataagaa gttatgaaga
     6061 tgtagttaac tacatgccaa atcaagttta tataggaaat agaagaccag aagaattaag
     6121 agatttacca atgccatggt gtgaacaaaa gattgaggga actagaaatg gtaagtttgg
     6181 agaaataatg cctcaagatg agttcatagc tttaatgcaa ataagtgatg catttgattt
     6241 agtaaaatta tcacaagaat ttattgatga agtaaagcca aaaatcgaaa ataactaccc
     6301 tgaaattgca ccatttgtag gtaaattaaa gggtgatgat atagaagaag gtaaagaatt
     6361 agtagcaaca cacatagctg aaggattata ccatgatgga aaatttgttg gttatgtaaa
     6421 aagagcacat gatgtagatg ttaacttaaa tgcccataca atgtttgaaa atctagtagt
     6481 aaaagcatct ggagttttat ctgctattca aatgctaaga catagcaaaa tagaccctgc
     6541 tgaaatagat tatgttattg agtgttcaga agaagcttgt ggagatataa accaaagagg
     6601 tggaggaaac tttgctaaat caatagctga gatagcagga cttcaaaatg caactggttc
     6661 tgacacaaga ggattttgtg cagcaccaac tcatgcatta attcaagcag cagctttagt
     6721 aaaagctggc atacataaaa atgtaatggt agtagcaggt ggagcaagtg ctaaacttgg
     6781 aatgaatgct aaagaccatg ttaaaaaagg tcttcctgta cttgaagatg ttgttggagg
     6841 atttgcagta cttgtatctg aaaatgatgg tgtaaatcca gttataagaa ctgatttaac
     6901 aggtaagcat actgttggaa ctggttcttc accacaagca gttatgacag cacttataac
     6961 ttcaggtctt gatagagcta atttaaaaat aacagatgtt gatgtgtatt cagttgaaat
     7021 gcaaaaccca gatataacta agccagcagg agcaggagat gttccagaag caaactacaa
     7081 aatgataggg gcacttgctg ttaaacgtgg agacttagaa aagaaagaat tgaaagattt
     7141 tgtttctaac aaaggattac caggatgggc accaactcaa ggacatatac catcaggagc
     7201 tccttatata ggatttttaa tagatgattt aactacagga aatagaaata gagctatgat
     7261 agttggaaaa ggtagtttat tcttaggaag aatgactaac ttatttgatg gagtatcttt
     7321 tatagctgaa agaaatacag gtgttactga agagacttca ggaatatcta aggatgaaat
     7381 taagaagata atagctgaat ctatgaaaaa actagcatta gatatgttag aagaataggg
     7441 gtgaggatat gtcaaaaaaa gtaatcgcag atgtattctt agaagtagct aatgcaatag
     7501 aaagcggcga atttggcaaa aaagtaaaaa ttggtgttac tacacttgga agtgaacatg
     7561 gtgtagaaaa catggttaat ggtgcacaat tagcaaaatc taatttattt gatattgtgc
     7621 ttattggacc aaaagtggaa actgaccttg aagtagttga agttaatgat gaaaaagaaa
     7681 tgcatgcaaa aatggaagaa ttattagatt caggatatat tgatgcttgt gttactatgc
     7741 attataattt tccaataggt gtatctacag taggtagagt aataactcca gcaaaaggaa
     7801 aagaaatgat acttgcaaca acaacaggaa caagtgctac taatagaata gaggcaatgg
     7861 taagaaatgc catttatggt attgctacag ctaaatcaat gggtaacaaa tgcccaaaag
     7921 ttggaatact taatgttgat ggagcaagac aagttgagaa gtgcttaaaa gaattaaaag
     7981 ataatggata tgacatggag tttgcggatt caattagagc agatggtgga tgtgtaatga
     8041 gaggtaatga tttacttgta ggtgcacctg atgttatggt tactgataca ttatctggaa
     8101 atatatttat gaaagtattt tcttcatata ctacaggtgg agattatgaa gctcaaggct
     8161 ttggatacgg acctggagtt ggagaggact atgatagaaa ggtacttata gtatcaagag
     8221 catcaggttc tccggtagta gcaaatgctt taaaatacgc ttatgatgtt gtaaagggag
     8281 atataagtaa tgttgcaaga aatgaatttg caaaggttaa aaaagcaaaa tttgatgaca
     8341 ttatatcctc tcttactaaa aaagaagtta aagctgaaaa agtagaagtt aaaatgccag
     8401 ataaagaaat tgttactcgt caaatagctg gtgttgatat aatggattta gaagatgcag
     8461 tatctgagtt atggaaaaac ggaatctatg ctgaaagtgg tatgggttgt acaggtccaa
     8521 tagttttagt aaatgaagct aaaggagact tagcagttga aactttagtt aaagctggat
     8581 atactgcaaa ataagtacat tttttatatg taaataagaa catatagtta taattttatt
     8641 gattataatt atatgttctt tttattttat atcttgtcaa tatttatata ttaacacaat
     8701 ccatttattt gattctctag ctaatttatt atatttattc aattaaaatt aagctttcta
     8761 actaaataaa aactaatgaa gtattaaaat gaaattgata aaatatgaaa aaattttagg
     8821 aataaagtat ctgttagata aaaataagat taattagtga tataatataa ttaagataaa
     8881 atttattatt tggaggtaaa atcatgagca gagtaaaaaa tgtagtagaa ttgttggaaa
     8941 ctaaaggtgt tgatgcacta tatctaacaa agaaaactaa tgtaaactat ataagtggtt
     9001 ttcctgatga agaagcatat gcagtgattt gcaaagatgg aaacttttta gttactgata
     9061 gtagatatat ggagcttgca gaaaaggttt gcaaagattt tgaaattata aattggcata
     9121 attttgatag aagtgtggca aaggcagtta aaagtgtatg tgataaagtg ggtataaaga
     9181 aacttggatt tgaaagaact aatatagtgt ttgataaata tgaagaactt aaaaatctga
     9241 ttgagaagga taatggagaa ttaataccta cagaaaatat tgtagagact ttgagatatg
     9301 taaaagacaa agatgaaatc aaaaatacaa gaaaagcttg tgaaatagcg gataaggcat
     9361 tagaagaatt gattccacat ataaaagctg gagttagcga aattgaactg gctacaaggt
     9421 tagagtactt tatgaaaatg aacggagcac aaaatatagg gtttgaaact atactgatat
     9481 caggagcaaa gacttcattg cttcatggta agcctagtga taagattata gaaaaaggtg
     9541 attttgtact tatagactat ggtgctatgt ataatggcta tatatctgat acaactagaa
     9601 cttttatagt tggaggagct tctgaaaagc aattagaaat atataattta gttaaggaag
     9661 ctcaaaatgt aggggttgag aacatgaaag ctggtgtaca tgcgacaatt ccagatgctg
     9721 agataagaaa agttgtcaaa aaatatgaag actattacta tcaaggtata ggacatggag
     9781 tcggtagaga tgttcatgaa gaacctttca ttggtaatta tggtgataaa atcatagaag
     9841 agggatgtat aataacaatg gaaccaggta tttatttccc tggatggggt ggagttagaa
     9901 tagaagatac tgttttgatt actaaaaatg gtccagaaag acttactaaa ttccctaaag
     9961 atttgatgat tttagacaaa taatttaatt tatatatatt tttttacata aaatataaca
    10021 taatctcact attaagctct atttacatat tatagtaaag agggcttaat tttattgtga
    10081 gaggtgatag tatatatgta taaaaaacat aaatttataa aaaatataaa aaaagcctgg
    10141 tataaaatca aattaattga tagatgcctt ataattgtaa tggcaatatt aatgtttcaa
    10201 tctatatata acttatttgt taatgaagta aattcacaag atactacaac tattgatgta
    10261 gtagtaagaa ccacttcagc agctatattt gggtattttt taagtgctaa ttttataaag
    10321 agacctttaa ggaagtatac aaatactgat gtatcttcaa atctttttat agataataat
    10381 ttatccccaa aaggtcaaga gtctaatcaa aataatataa tgaatgtcaa aaataccatt
    10441 ggatttactt cagaagctga taattatgaa aagaaaatac ctattaataa taatgaaggt
    10501 tttgaagaag gagaaactag tgaattgcaa attattatag ctactgtaat ttgcatagta
    10561 gcattaacag tactttttgt tgtaagaaat tttacaacta caacatcagc ttctttaggt
    10621 actatttcac agatgagaga ttttgtctca ggatgcgtgg gttttttgct aggttgtcca
    10681 agtaaacctg attaaaaaag tattatcaat aaaaggtatt ttaaaaagta tcagtataat
    10741 aatatttaga tttaaatgta tacaattata attctgtaac attctatatt gtatttttat
    10801 actgatactc taaactatac tatttattaa aatattttaa cattgtattt aaacaaaata
    10861 ttatatctgt ataatataaa tttagtttat atgaatagat gccatatact caataaaaag
    10921 tttcatacta tgagatatgt attgatttct tctccaaaga accccaatat ttgcagtaat
    10981 tgcacgttct aatggtattg aacagagatt ttctgtattt tgaaatattt ctttatacaa
    11041 tattgttgaa gccaagtcat tttctagtaa ataacgtatg gtagaaagtt gatttgagtg
    11101 taaaattata tttggcttag ctttttcaag tctttttgta ataatcttat agtgataaga
    11161 accttcagat aagattacaa aaggtacatt ttttaacata taattcgata taataggatg
    11221 ttttgccaat tcatttttgg gatttgtaac taagtataat tctgttttat agattgtctt
    11281 tgaatctata tcatcataaa tatcactgtc aattatacca atacaaaaat caagtgtaga
    11341 ttcttcaatc attttagctc caacaaatgt tggaacttca aaaattttaa gctctatatc
    11401 tggataaatt acattaaacc taggaagtat ttttgaaagc aaaaacgtac ctaaaactgt
    11461 aggaatacct attttgagag aagcttttct cttttttcct aaatcaagtg cgtcacattg
    11521 aaaatcctca aattgtttta taaaatgttt tgacttgtct aaaaaaattt ttccttcagg
    11581 cgttaactct attttattac ctattctgta aaaaagttca aagccaagtt ctttttctaa
    11641 ttctttaatt gctaatgtta tggatggttg agaaatatga atactttccg cagccttagt
    11701 catgttttta tatttacaga cagtttgaaa atagtataaa tagtttatat tcatttggta
    11761 ttagttcctt tcatttacat attagtgaca agtatataat taacaatagc ataagttttg
    11821 tatattgttg taaaaaaata gaatagtttt aaactatcat agcataagtt tttgatattt
    11881 tcaatctatt aagaatagtg ctattattaa attaacaaaa gagaatagct ggtatggttt
    11941 agagtaaatc aatctatatt acagttatat caacgaatat caaaaaatta tctattaaaa
    12001 aataaaaatt atttttacaa ttaaattgtt aattaaatca taaagaaaaa agtgatatta
    12061 acaagataaa atttttttaa tcagaaatgt taatttaata acaaaataga gtattgggga
    12121 gaaaggagaa atatattttt taataatatt tgttaattta ataacgaaaa atgaaaggga
    12181 gtgatttagt gaagtttgaa ttgatggatt ttttaatgaa tccttttgtc cttatgtttg
    12241 ctgcagtaat tacaggaatt ttatttggaa aaattaaatt tgggaagttt aattttgggg
    12301 tatcaggagc attatttaca ggattattta ttggatggct tgcatatagc ttggggaatc
    12361 taataatagc aaaaggggaa acagcagcag gatataaggc agcaactgta atgatgggga
    12421 atggaattat ttcttctgac ttctttgatt tctttttaat aatatttgtt gcagcagttg
    12481 gtctattggc agcaaaagat atgaaagctg tattaaagaa gtatggagca agatttgtaa
    12541 ttttaggagt tcttataact tttataggtg gctctatgac ttatgcaatg actttactat
    12601 caagtgataa aggaagtagt gcttatgaag tttctggcgt ttacacagga gcattaacaa
    12661 gttcgcctgg attagctgct gctttagaaa cagctggtaa acatgcagaa gatgtatcaa
    12721 aagaatttga aaaagcttca ataaaagata aaaaagaaat tttaaaagta gtcgacccag
    12781 aaggcaaatt ggatgtgaat acaactacat cactgactca agagcaaata gataagtata
    12841 ttgcatatgc tgaagctggt gttggtatag gtcatgcagt cgcatatcct tttggagttt
    12901 taatagtaat cttaggtgta aatttccttc caaaattatt taggatggac ctaaaagaag
    12961 aaagaagaaa atatgagaag gaaatgaagg aagcaagaga tagtgtttct ggtaaaacga
    13021 taccagaagt tccatttaat ataataacat ttttcttgac atgtttagct ggatacttag
    13081 ttggaggaat acatgtattt atgggaccac tagggtactt cacactaggt gcaacaggag
    13141 gttcactaat tgtatctcta gttcttggat atataggtaa gataggggta gtaaatttca
    13201 gaatggaaga aaaggtttta aatattttaa aacaaatagg gctagtgttt ttcttagcaa
    13261 tagttggatt aagatatggt ggaaaagtag ttgattcaat tatgacatct ggtatgcacc
    13321 tagccttagt agcaatagca gtaggtgtta cagctatgat gataggattc ttagttggca
    13381 aatacgtatt taaattaaat tggattttat tatctggagc tgtctgtggt ggtatgacat
    13441 caacaccagg tcttggagct gctgttgatg ctcttgatag tgatgaccca gcagcaggtt
    13501 atggtgctac gtatccattt gcattattaa ctaaagttat attggttata gttttacaca
    13561 aacttccaat gtaaataaga ttttatatgg ggggatattt atgaataatg aaggagcatt
    13621 tgaagaatta agtggaagat taagaaataa agaattgtgt gatttaataa tgaatgcaga
    13681 tgaagctgct aaaattatag aggatggcat ggttattgga gttagtggat ttacaccttc
    13741 aggctatcca aaagcagtac cattagcagt ttcagaaaga gctaaaagtg gagaaaagat
    13801 aaaattaacc gtatattcag gagcatcttt aggtccagaa gttgatggag catggtcaga
    13861 agcaggtata attgaaagaa gacttcctta tcaaactaat tcaatactta gaaataatat
    13921 taataaaggt gttgttgatt atatagatat gcacctaagt cattctactc aatttttaaa
    13981 ttatggaact atacctaaag tagatgtagc tatagtagaa gcacttgcaa taactgaaga
    14041 agggaatatt ataccaacta gtgggatagg taattctcca tcttttataa aaagtgcaga
    14101 taaagtaata gtagagataa atcttgcaaa accaatggaa atggaaggta tggcagatat
    14161 atatattacg gaaaatccac caaatagaaa accaatagaa ataaatcatc ctaaggatag
    14221 aattggaaca acatatatac cttgtggttt ggataaaatt gcaggagtag taattaccaa
    14281 tatgcaagat aagacccgtc cattgggggt tgtagatgaa gcttcgaaaa aaatatcaaa
    14341 taatattatt gcttttttaa gagaagaagt aaagtcaggc agattatcaa agaatttact
    14401 tcctcttcaa tctggtgtag gaagtgtagc aaatgcagta ttatatggat tatgtgaatc
    14461 tgaatttgaa aatttaactt gttatacaga ggttgtacag gactctatgt tggatttaat
    14521 aagaatgggt aaagttacaa tggcatctac tacatctgta agtccatctc cagaaggatt
    14581 aataaaattt gaaaaagata ttgatttttt taaggataag attatattaa gacctcaaga
    14641 aattagtaac aatccagaaa tagccagaag aattggtgta attgcaatga acactgcaat
    14701 tgaagttgat atttatggaa atgtaaattc tactcacata atggggtcaa agatgatgaa
    14761 tggaattggt ggttctggtg attttgctag aaatggagca ataactatat ttagtactga
    14821 gtcaattgca aaaaatggtg atatatcatc aatagtacct atggtatctc acgtagacca
    14881 cactgaacat gatgtaatgg taattgtaac agaacaagga tatgctgatt taagaggtct
    14941 tgcacctaga gaaagagcta taaaaataat agaaaattgt gcccatccag attataaaga
    15001 acaacttagg gattatttaa atagagcttg taaaagtgga gcaaaacaaa cacctcacat
    15061 attggacgaa gctttatcat ggcatagtaa atttatgagt acaggtacaa tgaaaaaggc
    15121 tgaaactttt aaaagtgcat tataaaatat ttaataaatt ggaggtagat tttaaatgga
    15181 aaaagcagtg gaaaactttg aagatttaag taaggaatac attaatggtt atattgagag
    15241 agcaagaaaa gctcaaagag agtttgaatg ttatactcaa gaacaagtag ataaaatagt
    15301 aaaaatagtt ggaaaagtag tgtattataa tgctgaatat ttagctaaac ttgctgtaga
    15361 agagactgga atgggagtat atgaagataa ggtagctaaa aataaaagca aagcaaaagt
    15421 tatatataac aatttaaaag ataaaaaatc agttggtata attgatatag atagagaaac
    15481 tggaataaca aaggtagcta aaccagttgg agtagtagcg gcaataactc cttgtacaaa
    15541 tccaatcgtt acacctatga gcaatgcaat gtttgcactt aagggaagaa atgcaattat
    15601 tatcacacct catcataaag caattggatg tagtacaaaa actgtagaga tgattaatga
    15661 agaattagaa aaaataggag ctccagaaaa tttaatacaa atacttgacc aacaatcaag
    15721 agaaaataca agaaatttaa tttcatcagc agatgtagta attgccactg gaggaatggg
    15781 aatggtaaaa gctgcgtact caagtggaaa accagcactt ggtgtagggg caggaaatgt
    15841 tcaatgtatc atagatagag atgtagacat taaagaagca gtacctaaaa tcatagcagg
    15901 aagaattttt gataatggta tcatttgttc aggtgaacag tcagtaatag tagcagaaga
    15961 aatgtttgat aaaataatgg atgaatttaa aaataataaa ggttttatag ttagagataa
    16021 agtacaaaaa gaagctttca gaaatgctat gtttgtaaat aaatctatga ataaagatgc
    16081 agtaggtcaa tcagttcata caattgcaaa aattgcaggt gttgagatac cagaagatac
    16141 aaaaataata gtaatagaag ctgatggacc aggagaagag gatattattg caaaagaaaa
    16201 aatgtgtcca gttatatctg catacaagta taaaagtttt gaagaaggtg tagctattgc
    16261 aaaagcaaat ttaaatgtag aaggaaaagg acatagtgta tctatacatt caaatacagt
    16321 taaaaatata gaatatgcag gagaaaatat agaagtatca agatttgtta ttaatcaatg
    16381 ttgtgctact agtgctggag gaagtttctt taatggtctt gcacctacta atactctagg
    16441 ttgtggttct tggggaaata acagcatctc tgaaaatctt gattataagc atctaattaa
    16501 tatttctaga attgcttatt atatgccaga aaatgaagtc cctacagatg aagaactttg
    16561 gggataaaat ttagacaaaa aatattcatt ctaaattaaa gtaggaatat attttaattt
    16621 agaatgaatt taagacataa attaaattta aattagttta ttggactaaa tttaaaatat
    16681 taagagacat atagaagaag gaagtattat aatttaaaat aaataaaaaa atctataaaa
    16741 gagaaggagt ggttttatta tggcattaat gacaggagct caatatattg aaagtttgag
    16801 aaaattaaat actaaggttt atatgtttgg tgaagaggtt aagaattggg ttgaccatcc
    16861 tatgattaga ccatctataa attgtgtagc agcaacttat gacttagctc atgacccaga
    16921 atatgcagat ttaatgacag ttacttcaaa tatcacaggt gaaaaaataa atagatttgg
    16981 tcatcttcat caaagtgttg atgatttgat aaaaaaagta aaaatgcaaa gactatgtgg
    17041 tcaaaaaaca gcttcttgtt tccaaagatg tgttggtatg gatgcgttta atgcagtgta
    17101 ttcaacaaca tttgagtgtg ataaagccca tggaactaat tatcatgata attttgtaaa
    17161 atacttaact tatatacaag aaaacgattt agtagttgat ggagctatga ctgaccctaa
    17221 gggagataga agtctatcac ctagtgctca acctgaccca gatatgttcc ttcatatagt
    17281 agaaagaaga gaagatggga taattgtaag aggagcaaag gcacatcaaa ctggttcaat
    17341 aaattcacat gagcacctta taatgcctac tataagtatg actgaagcag ataaagacta
    17401 cgctgtatca tttgcagttc cttcagatgc tgaaggagtg tttatgattt atggaagaca
    17461 atcttgtgac actagaaaat tagaagaagg tgcagatgtt gatttaggaa ataaggagtt
    17521 tggaggtcaa gaagctttag tagtatttga taatgtattt gttccaaatg atagaatttt
    17581 cttatgtgga gaatgggatt tctctggtat gttagtagag agatttgcag gataccatag
    17641 acaaagttat ggtggatgta aagtaggagt aggtgatgta ataataggag cagcagcttt
    17701 agcagctgat tataatggag caaacaaagc ttcacatata aaagataaac taatagaaat
    17761 gactcacctt aatgaaagct tatattgctg tggtatagca tgttcatcag aaggtcacaa
    17821 aacagaagct ggaaactatc aaatagattt acttcttgca aatgtgtgta aacaaaatgt
    17881 aactagattt ccttatgaaa tagtaagact tgcagaagat atagctggag ggcttatggt
    17941 tactatgcct tcagaaaaag actttaaatc agaccttaaa gttggaacaa gtggaatgac
    18001 tattggcgaa gtatgtaaca agtattttaa agcttcttca gtggcttcaa cagaagaaag
    18061 aatgagaata ttaagattct tagaaaatat atgccttggt tcatctgctg ttggttatag
    18121 aactgagtca atgcatgggg caggttcacc acaagctcaa agaataatga tttcaagaca
    18181 aggaaacata aatcaaaaga aagaattagc taagaaaatt gcgggaataa aaaaagagga
    18241 agctttaaat ttataaaaag ttgatatata aagggaaatt atatattaat gtgtattaat
    18301 taatgaaaaa atatgtagta taagagatag ttataaaatt atggtggttt ttagctaagt
    18361 aaagaaattt ttaataagga gaatttacac atgacctgtg gagttagatt ttgtgggggc
    18421 tgtaacccta gatacgaaag agggaaggct cttacaataa tcaaagagca cttcaatggt
    18481 agggtagatt ttagtatagc acaagagaac gtcgagtatg atttgctact tataattgga
    18541 ggatgcgcaa ctctatgcgc atcctatcaa caatataaag tgaaaaatga atgtgttaag
    18601 atgtgggatt ttagccatat agaaagagtt ataaatgtga ttgaatcagc aatttgtgaa
    18661 acttaaaaaa gctaaatggg gggatttcat tgagttggca agaattgtat caaagtaaat
    18721 tatgtagtgc tacagaagct gtaaaacaga ttaaaaacgg tgatactgta gtatttgcac
    18781 attgtgtagg tgaacctcct gcactagtag aggctatgat tgaaaatgct gaacaatata
    18841 aagatgttga gattaaacat atggtaagct tgggtagtgg tggatatact gctaagggaa
    18901 tggaagctca ttttagagta aatccaatgt ttgtaagtgg aaatgtaaga aaggcaattg
    18961 aaaatggaga tggtgatttt acacctgcat tcttccatga agtaccaaag ttgcttagag
    19021 aaaaaagatt aaaatgtgat gttgttttag cacaggtaac tccaccagat gaacatgggt
    19081 attgtagctt aggaacatca gttgattata cttatgaagc cattaaaact gctagaacag
    19141 taattgttca agtgaatgac cagtttccta gaacctatgg tgaggtagtc catgtatcag
    19201 agtttgacta tatagtggaa aaatcacaac ctttatttga actacaacct gcaaagattg
    19261 gagaagtaga agaagcaatt ggtaaaaatt gtgcttcatt aattgaagat ggttctactt
    19321 tacagctagg gattggtggg ataccagatg cagttatgtt atttttaact gataaaaagg
    19381 atttagggat tcattcagaa atgatttcag atgggacttt ggccctttat gaaaaaggtg
    19441 ttataaatgg taaatataaa aattttgata aagaaaaaat gacagttacc ttcttaatgg
    19501 gtactaaaaa attatatgac tttgcaaata ataaccctgc agtagaggta aaaccagtag
    19561 actatgtgaa tcatccagca attataatga aacaacataa gatggtttct ataaattctg
    19621 ctatacaagt tgatttaatg ggacaggtag ttgcagaggc tatgggactt agacaattta
    19681 gtggtgttgg aggtcaagtt gactttatac gtggagtgtc tatgggtgaa gatggaaagg
    19741 caattatagc tatgccttca ataactacga aaaaagatgg tacagtaatt tcaaaaatcg
    19801 tgtctattgt ggatgaaggt gcacctataa cgacatcaag aaatgatgtt gactatattg
    19861 taacagaata cggtatagca gaattaaaag gaaaatctct tagagaaaga gcgagaaatt
    19921 taataaatat agctcatcca agtgtaagag aaagtctagc agtagaattt gaaaagagat
    19981 ttaaggagaa atattaataa tagaggggtg ttaataatgg aagcacttag agtagttcca
    20041 aagatatttt actttgatac atttaaagaa tttaatgaag aatttaaaat aggaaaaaat
    20101 gatttagtaa ttactaatga gtttatatat gagccatata tgaaacctct tggaatagat
    20161 acaaatttaa tttttcaaga aaagtttgga acaggtgaac catctgatga aatgatagac
    20221 tccatgacaa aggaaatgaa gaaatacaat tttgatagaa ttattgcatt tggaggagga
    20281 acaatagttg atatatgtaa gatattagca cttgatgttc cagaaaagtc tattgattta
    20341 tttgaaggag aagtatcacc taaaaaagta aaagagttag tagtagttcc tacaacatgt
    20401 ggtacaggta gtgaagtaac aaatgtagct attgcagagt taaaatctaa acatactaaa
    20461 aaggggcttg cagtagaaga aacatatgca gactatgcag tgttaattcc agagacagta
    20521 aaagggttac cttacaaatt ctttgttaca agttcggtag atgctcttat acatgctatt
    20581 gagtcttatc tttctccaaa agcaagtcca tttacagaga tgtattctct acaagcaata
    20641 aaaatgatta tggatgggta taagaagata gttgataaag gagaagaaga gagatttaat
    20701 catcttagag actttgtact tgcatcaaat tatgcaggaa ttgcttttgg aaatgctggt
    20761 tgtgcagcag ttcatgcact atcttattca ataggtggag ctttccatgt tgcacatggt
    20821 gaagcaaatt atcagttctt tactgaagta tttaagatgt attctagaaa aaaacctaat
    20881 ggaaaaatta taaaatgtac aaaaatttta gcagatgccc ttgaatgtga ccctaactgt
    20941 gatgtttatg gagaattaga aaagttttta aataaattaa tagctaaaaa agctttgaga
    21001 gaatatggaa tggtggaaag tcagatagat gaatttacag atagtacaat agcaaatcaa
    21061 caacgactac ttgctaataa ttatgtagag cttagtagag aggaaataag agagatattt
    21121 gcaaatcttt attaatacaa ttttttattt atatgtatag tcaacataaa caatgctaat
    21181 tatatttatg tacaaataaa aataagggaa cttaaatttt aattaaagtt aagttctctt
    21241 atttttatat ggagttaaat ataagtatat ttttaattta aaatatgctt atatttaagt
    21301 ctattacttt atttgaaaca atttgtagaa tttcaaattc cttgacagta ataagtaagt
    21361 aattgtataa tcaaactgca atatattaat aatattagtg aaaatgaaag gattataaaa
    21421 tatgtataaa tcagaaaatt tttcaaaaaa atctgtatta ataaattcat ttttaagtaa
    21481 atttttaaaa ataattggat ggggtttggt aagcttattt acattatcag ccttagtact
    21541 ttcaactatt tccattataa ttggatgggc tgtaatactt cctattcaag tatgtgcagt
    21601 atttttactt ataggaggag tttgtatttt taaaggtaag agattaggag accaaatttc
    21661 tcgttataaa aaatattgta caattataaa caatagaaat attattccag tagaacttat
    21721 tgcagaaaac acatctaaat cattaaattt tataataaaa gatgtacaaa agatgataga
    21781 caaaaactac tttataaata cttatattga taaaagaaat aatcagattg tgttaacaaa
    21841 tgaagatttt gttccaccaa gatatgaaga tgtagcatat gaagtcaaag aagaagaaaa
    21901 gactgatgaa tccaatgaag ttgatacaat tataaataaa ggaatgaatt atctaacaca
    21961 aataaaagaa gctaataaaa atattaaatc agaatcaatg ggcgataaaa ttgtacaagt
    22021 agaagatgtt acaagtaaaa tatttgatgt tgtaaaacat gacccatcaa aacttactca
    22081 aatacaaaaa tttatggatt attatcttcc aaccacttta aaactattaa attcatatca
    22141 tacattggaa gaacaaggaa ttgatagaga aaatataaca acaactatgg aaagtattga
    22201 aaatacaatg aatacgattg tagtagcttt tgaaaatcaa ttggactatc tgtttgaaga
    22261 tgaagccatt gatatttcta cagatattac tgttttagag aatatgttag tccaagaagg
    22321 attaacgagt ggtaaatttt aacttcaata gaaaaaatat tctgttattt ttaaacaatt
    22381 aattagtcat aaagtataaa atgtgtatta tataagttaa tcagtacttt atgaaggaag
    22441 aggagagaaa gatacaatga ataatttaga tgatatacca gttatgccaa ctttgacact
    22501 tgacccattt ggagaagaat caaacactaa tgatatagat aattctgact tattaatgaa
    22561 aaaggatgaa aaagacccag aagaagaaaa actgtctgaa tctgaacgca agatggtaaa
    22621 ggaatttgcg gaaaaaatag atattacaaa tacaaatatg attttgcaat atggagctgg
    22681 tgctcaaaaa aaggtagcaa gtttttctga aacagcttta aagagtgtaa agacaagaga
    22741 tttaggagaa gttggagata tgcttacaaa tctagttact gatttaaaag cattttcagc
    22801 agatgaaaaa gaacaaagtg gttttttagg aatttttaaa aaggcaaata ataaaatttc
    22861 aaatttaaaa actaagtatg atagtgcaga ggtaaatgtg gataaagtaa gcaaagagct
    22921 tcaaaagcat caggttaaaa tattgaaaga tatagcaatg cttgataaga tgtatgaatt
    22981 gaacttagct tactcaaaag agcttactat gtatattata gcaggaaaac aaaaattaaa
    23041 ggatatgaaa gaatatgaga tgccaaagtt gagagaaaaa gctcgtttat ctggttcaac
    23101 agaagatgct caatctgtaa atgatatggt ttcactttgt gacagatttg aaaagaagat
    23161 tcatgactta gaattaacta gaatggtatc gcttcaaatg gctcctcaga taagattggt
    23221 tcaaaatagt aataatctga tggcagaaaa gattcaatca actatagtaa ataccattcc
    23281 attatggaaa aatcaaatag tgcttgctct tggaatttct cacttaaatc aagctatgaa
    23341 agcacagcgt gaagttagta atatgacaaa tgagctttta ttaaagaatg cagaaacttt
    23401 gaagatggga acaatagaaa cagcaaaaga atcagaaaga ggaattgtag atatagacac
    23461 aattaagaaa actaatcaat ctctaatatc tactattgat gaggtagtta agatacaaca
    23521 tgatggtaga ataaagagac aagaagcaga agttgaatta tcaaaaatag aaaatgaact
    23581 taaaagcaag cttcttgaat ttacagttaa ataaaaatta tactaagata aaaagagact
    23641 gtctcaaaat tggatatgtc cctgtcaagt agacagactt aaaaaaggct atctttactc
    23701 ggaatgagtt cgatattcaa tcggactcat tccgtttttt aattgtattc tttcattatt
    23761 ataaaaataa atataatcat ttattagact aatcatttcc tttggatctg tagtatcaat
    23821 taaatatatt aattcagatt taaaatgact gaaaaaactt tctataggag cattatccca
    23881 gcagttgccc cttcgggaca ttgattgtat aataccatta tccttaagcc ttttagagta
    23941 agatctactt gtatattgtg aaccttgatc tgtatgtaaa atacaatctt tagctaaatt
    24001 catatttatt agttgattta ctgtattatt aactaattta gtatccattt ttgtacttat
    24061 ctcatatgcc actatttcac cattaaataa atctttggct acattcatat ataagaattt
    24121 tttaccgata ggtatgtatg ttatatccat acaaattttt tctaatggtt gattagctct
    24181 aaattcacga tttaatatat tatcatatat ctcatatgat ttaaacttac gtctatatac
    24241 tttctttcta ataatagatt taatacctag ttctttcatc aacctatata ctctcttatg
    24301 attaataggg gtatcaagta ttttatttaa ataagtacaa attctttttc taccataagt
    24361 tcctctatat tttttatgta tttcaattat ataatcctta ataattctat ctttgatacc
    24421 cctatcggaa gattttttag aataacttag ccatttatag taaccgcttc ttgacacact
    24481 tatcaactta cacatactag aaatactata cttcctagac agaagtttaa ttgttttaaa
    24541 tttatcgctt actttgactt gtccaatagg gtacttaact tttttaagaa ttcattctcc
    24601 atgcgtaagt acttcaattc ttcttcaaca gatttaaatt ttctattatc attttctaga
    24661 ctaatatttt taaatctgcc cctagtttca tcatcaaatg cagttttgcc tttattttta
    24721 taatctttta cccagttttg aacttgtgtt ttgcttctta tattcagcat ctcagcaatt
    24781 ttgtatgatg agtatccttc ttttatatat aagtttacag cttttagctt aagttctttg
    24841 ctatattttt tgtgtttttt agacatagaa aaaccccctt agagtatacg ctttttagac
    24901 ctattataat agccttttat ttaaatgtct actataaggg gattatacta aaatagagat
    24961 aagtctcttt ttcattgttt aaatgattaa agtatattta tattataaat ttctattatc
    25021 ttttaacata acatcatgag ctccaccttc aactatacta gtagaagata caagtgtaag
    25081 tttagcattt ttttgaagtt caggaatgct aagtgctcca cagttacaca tagtagaacg
    25141 aactttactt aaagaaagag ttacattgtc tttcaaagaa ccagcataag gaacataaga
    25201 gtcaacacct tcttcaaaag aaagtttctt atctccacca aggtcatatc tttgccagtt
    25261 tctagcacga gcagaacctt ctccccaata ctctttcata taactaccat ttatattaac
    25321 tttgttagtt ggactctcat caaaacgaga gaagtatcta ccaagcatta taaaatctgc
    25381 acccatagct aaagctaaag ttatatgatg gtcataaacg ataccaccat cagaacaaat
    25441 tggaatataa atacctgttt tttcaaagta ttcgtcccta gcttgagcaa cttcaattat
    25501 agaagtagct tgtccacgtc ctataccttt ttgttcacga gttatacata tagaaccacc
    25561 accaatacca actttaacga agtcagcacc agcttcagct aggtaaagga atccctcacg
    25621 gtcaactaca tttccagctc ctaccttaac tgtatcacca tatttttcac gaatgaaatc
    25681 aagtgttatt ttttgccact cagaaaaacc ttctgaagaa tctatacata aaacatcagc
    25741 accagcttca actaaagcag gaacacgttc agcaaagtct ctggtattaa taccagctcc
    25801 aactacatat ctcttagaag aatctaaaag ttcaagtgga ttttctttat gagaagagta
    25861 atctttacgg aataccatat acataagatt accattgtca tcaagtacag gaagagaatt
    25921 aagtttgtgg tcccatataa tgttgtttgc ttcctttaaa gtaacatctt tgttagcata
    25981 aactatagat gacataggag tcataaattc actaacttta gtatctaaat ccatacgact
    26041 tatacgataa tcacgacttg caacaatacc taataattta ccagttgaag ttccatcttc
    26101 agtaacagct actgtagaat gtccagtttt ttcttttaag tcaagtatgt cttttaatgt
    26161 gttatcaggt ttaatatttg aatcacttac aacaaaacca gctttgtggg atttaacacg
    26221 tgctaccata gcagcttcat cttcaatagt ttgaaaaccg tatataaatg aaataccacc
    26281 ttctttagca agtgcaatag ccattttgtc atcagaaaca gattgcataa tagcagaagt
    26341 caaaggtata ttcatataaa tatctgcttc ctcgcccttt ttaaatttag taacaggtgt
    26401 ttttaaactt acattagcag gtatacaatc agtagaagag aaacctggta caagaaggta
    26461 ttcactgaaa gtatgtgatg gtgtatcaaa ataaaacgcc attttttaat cactccttat
    26521 atttttatac tttttataat tgatagtatt aattataact tattctttaa ttttattaaa
    26581 gtattttgtc aaatattgaa atttttgaaa aatttaaact attttaattg aatttgttta
    26641 atatatattg ccttataggg taaagttgta tattaaataa tgtttagtgt ttaatagtag
    26701 ctaatttgaa attaatcttt agttattcat ataattacat ttgtatagtt tatattgata
    26761 atattgctag agagtgcata aacctcaaaa atacagataa attaaatcta tattagtata
    26821 tccaaaagta catttaataa atttatttaa ctgaattatt attttcattt ctattaaatt
    26881 taaatatttt ataaaaatag tattatttac aaaatcatat actccaaaat actacataaa
    26941 taaaattaaa caaaaactaa aatgacaaat gtcattatct aaagtgacat agaaacggtt
    27001 tcttaaagtt gttactataa aatataaact ctataataaa agtataacaa aagggaatca
    27061 tatcgatata gaatataatt caagaggagg taaaattatg agtagttcta atcaatcgac
    27121 aataaagaca tctatacagc gagtagggaa atttttaagt ggtatggtaa tgccaaatat
    27181 aggagctttt atagcatggg gtcttataac agcattattt ataccaacag gatggatgcc
    27241 taatgaaaaa ttgagtacta taggcgaccc aatgataaaa taccttttac cactattgat
    27301 agcttatact ggtggtaaag caatagcagg acaaagaggt ggcgtaatag gtgcagcagc
    27361 agctatggga gtaattgttg gggcagatat accaatgttt atcggagcaa tgataatggg
    27421 accatttgca ggatgggtaa ttaagaagtt cgataaattt gtagatggaa agataccaac
    27481 aggatttgaa atgttagtaa ataacttttc aataggtata ataggtatgc ttcttgcaat
    27541 actaggattt tatgcaattg gaccagcaat agtagcaggg acagctctta tagaatctgg
    27601 agttcaattt atagttagca aaagtttatt gcctttagtt tcagtattta tagaacctgg
    27661 aaaagtatta ttcttaaaca atgcaataaa tcatggtata ttagggccta taggtatagc
    27721 tgaggcaaaa gaagcaggta aatctataat gttcttacta gaaagtaacc ctggaccagg
    27781 tttaggagtt ctattagcat attggatgtt tagtagagga agtgtaaaac aatcagcacc
    27841 aggagctgta ataatacatt tctttggtgg tatccatgaa atttacttcc catatatttt
    27901 aatgaatcca gttttaatat tggctacaat ggcaggtgga gcagcaggaa tattgacttt
    27961 ttcaatatta ggagctgggc ttgtagcagc accatcacca ggaagtatat ttgcacttat
    28021 ggcactagct ccaaagggag gattacttcc agtattagca ggggttgcag tggcaacagt
    28081 tgtatcattc ttagtggcag caccatttgt taagagagct tcagcaaatg aaagtgaaga
    28141 agacagtact tctttagaag aagctaaagc aaaaatgagt gatatgaaat ctgcaagtaa
    28201 gaactctgag aaaaatattg agaaaaaaca gcttgaagta aatgagatta agaagattgt
    28261 atttgcatgt gatgcaggaa tgggttcgag tgcaatggga gcttctagat ttaaaaatag
    28321 aataaaaaac ttagatttag atatagaaat tacaaattca tctgttgata atcttccaga
    28381 tgatacacaa atagtagtaa ctcacaatac attagttgaa agagttgcta agaacaattc
    28441 aagtgttgag atagtttcaa taaacaattt tttaaatgac ccaaatttag atacattatt
    28501 taaaagatta gaatctaaat aaaaataaaa agtaccacta attaggagtg gataatttga
    28561 aaaaaaagaa gattacatct aggcaaaaaa agataatact aatgatagta gaaaattcaa
    28621 agaaaaacat tccaataact atttctgaga ttgcagggac gttagagtta agttcaagaa
    28681 ctgtacttag agatatgtct ggaattgaaa aatggtttga tgaaaatgat tttaactttg
    28741 taaaaaaacc aggagtagga ttgattttag aggaaaatat agaaaatcaa aactttataa
    28801 ttgagttgtt agaagaagaa aaaatagaaa aagaatacag caaggaagaa agaaatttaa
    28861 ttatattatc aaagctacta gtttctaacg agccagtaaa atcttattat tttgcaaaaa
    28921 tattaaaggt atctgaaggg gtactgaata atgatttttc attagcaagt aaatggttgg
    28981 aaagatttga tattgagctt gttagaaaac cagggcttgg tgtctaccta aaaggtcaag
    29041 aaaaaagctt tagagaggca tatgtaaatc ttatatacga ttcattcaat gaaaaagaaa
    29101 tactagatat ggtcagaaat ataagtgaaa atatacaaac agataaagca atagaaattt
    29161 taagtgaaaa tagactttta aatttaatgg ataggtgcat aataataaaa gttgaagcta
    29221 cattaacaaa gaagctttca gatttagatg taaatttagc tgatagtgca tatatagggc
    29281 ttgtagttca tatttcatta gccttacaga ggataaaaaa tggtgaaaat ataactatgg
    29341 ataaagagtt tctaaaagaa ttatctataa cagaagagtt taaattagct aaagaaatcg
    29401 taaaaggtat ggaaacagat tttaacatgg atataccagt agatgaggtt ggatatataa
    29461 ctatgcatat aagaggtgca aagcaaaggt catcttcaaa tcataaggct ttaaacttgg
    29521 atgatataga aataatggaa attacaaata agatgataga tttggctgaa gatgaattta
    29581 aaataagttt aaaaaatgac gagaggttat ttaaagacct agcaaatcac ttaggacctt
    29641 ctataaatag attgaatatg ggattagaaa taagaaatcc tcttttagat gaaataaaaa
    29701 gcaagtattc atatgcctat gatggagttg aaaaaatttc tagaattata aaagataaac
    29761 taaatataaa ttcaatacct gaatcagaaa taggatatat tgcaatgcac tttgcatcag
    29821 ccatagaaaa aaatcttatg atgaatacta atataaatat tgttgtggca tgtcccactg
    29881 gaataggtac ttcaagattc ttatcaacta agattgaaaa taaatttcct aatttaaata
    29941 tacttgaaac catatcagct ataaacatag atgaagagta tttaaaggga aaagatgttg
    30001 atttaatagt gtctacagtt gagttaaata caagtttaaa ttatatatgt gtaggtccat
    30061 ttatgagttt agatgatgaa cagataatca aggaaaaaat aaaatctata gctcaaaata
    30121 aattaattaa tttaaataca aaaaatgata ctaaaagtaa gaataaagta tatgaacaga
    30181 taacagaaag tatgaatata ggaaaagata ttcttcaatt tttagaggaa attagatttg
    30241 aaaaatttga aagtaaagat ttaagtgagc ttattgaaga ctcatcaaaa atatttgcaa
    30301 aatctagtga agatataatg tctataaaag aatcgttaaa agaaagatta aaaatctcaa
    30361 ttccatatat agaagaatca aaaattctat tattacattg tatgagtgaa agaatagata
    30421 ttatgaagtt atcaataata aaactggaga atcgaatcgt gctagattca aatgaagaaa
    30481 tcgacaatgt agtttttatg ttacttccta aaaattcacc aagttatcaa agacaaataa
    30541 tgagtgaaat aagtggttca ttaatagaca atataatttt tactaataag ataaataaat
    30601 tctctataga agagatgaca ttagaggtaa aagatatagt ttttaatttt tatacaaaca
    30661 gattaaaagc atttatagat gaataaaatt aatattaaaa aggaaggttg atactatgag
    30721 taaagtattg aatgagaata atatattttt agggttagat agtgtttcaa aggaagaagc
    30781 tataacttta gcaggaagaa aattagttga aaatggatat gtaaaagaag aatatatacc
    30841 agcaatgcta gaaagagaaa aagtaatgac tacatatatg ggaatgggag ttgctattcc
    30901 acatggtgta aatgaagcaa aaaaagaaat attatcttct ggaatagtta tactacaatt
    30961 ccctaatggt atagattttg atggagaaaa agcatactta ttaataggaa tagctggtgt
    31021 tggagatgaa catttagaaa tactatctaa tatagcagta gttttagatg atgacttaac
    31081 agaaagacta aaaaattcaa atgacaaaca agcttttatg gaagcttttg ccaaataatc
    31141 ttaggaggga tttaaaatga aaaaggcaat ccagtttgga gcaggaaata ttggaagagg
    31201 ttttattgga ggcttgttag ttaagtcggg ttatcatgta gtatttgctg atgtaaatga
    31261 ggagatatta aactcaataa ataaagataa aaagtatact atacacataa gagatgtaga
    31321 atgtatagat gaagtaattg ataatataag tgcggtttca tctataaaag aagaaataat
    31381 agatgagatt gtacaggctg aaataataac tacagcagtt ggacctttag ttttgactaa
    31441 aatagcctct acaattgcaa aaggtataaa ggctagaaaa gaaaagggtt taacaagtaa
    31501 tctaaatata atagcctgtg aaaatgcaat atacgcaagt tcttctttaa aagaagaggt
    31561 acttaagtat ttaaataagg aagaagtaga atatttagag atatatgttg gttttccaaa
    31621 ctgttcagtt gatagaatag ttcctcctgg taaaaatgaa aatcctcttg atgtaacagt
    31681 tgaaaatttt tatgagtgga atgttgaaaa acaaggattt aaaggggaaa taccaactat
    31741 agttggaatg aatttagctg acaaccttat ggcttatata gagcgtaaat tgtttacact
    31801 gaatacaggt catgctataa cagcttatat aggatattta aaaggatata agactataga
    31861 agagagtata aaagataaat ttatctgtga tatagtcaaa agtgcaatgg tagaaagtgg
    31921 agaaggattg attaaaaaat acaattttga ctcagaagcg cactataaat atattgataa
    31981 aattttaaat agatttaaaa atccatatct taatgatgat gtattaagag ttggaaggga
    32041 accattaaga aaactaagtg ataaagatag attgattaaa cctttaatga cagcaaaatc
    32101 atatggatta tcagttgaca atttgattct tggaataggt gcagcgcttc attataataa
    32161 tagtgaagat actcaaagtg tagaattaca agagttgata aagtctaatg gtgtaaaaaa
    32221 agctgttgct aaaatagcta atataagcaa tgacgaagaa cttttaaata atatcgaaaa
    32281 aagttatata tttatgaaaa atttataaat ttacttgaaa aaaagtagtt ctgataaagt
    32341 aactataata tattattcta cacagtttga attatttgtt gaataataga gaattataat
    32401 atataattaa aaggaataaa ttaatatatt tacctgtata tgtttgataa tatggttcaa
    32461 atgtttctac taagctacca ttaatagctt gactacagga gtgaagaaga tatagtttat
    32521 acttatttta aattatatat taagttaatt actttgaatt ttaagctcct gtctatgata
    32581 tagacaggag cttttttagt attttaatat aaaatactta caagaataga tagcaaaatt
    32641 agaacaaata taattttttt attaatataa ctttagaaag ggctaggtgg aagttcaatg
    32701 aaggctttac aagaaaagat attgagagaa ggcagtgttt caggaaatga tatactaaaa
    32761 gttgatagtt ttttaaacca tcaaattgat gtagcttttt taaatgaaat aggaagagaa
    32821 tttaaagaga gatttaaaga agaaaaggtg gataagatat ttacaataga ggcttcagga
    32881 atagctatag catcaattgt ttcacagtat tttgataatg cacctgtagt atttgcaaaa
    32941 aaatcagaat ctaaaaattt ggataaagat gtatatgaga ctaatgtata ttcatttact
    33001 aaggcaagag aatattcagt taaagtttct aaaaagtaca taaacaaagg tgaaaatata
    33061 ttgatagtgg atgatttttt ggcaaatgga agagctgctc ttggacttaa agatttaatt
    33121 gagcaagcag aagctaattt agttggagta ggaattgtca ttgaaaaagg atttcaagct
    33181 ggaggagcac ttttaaaggc taatgatgta agattagagt ctttggcggt agttgaatct
    33241 atagataatg gaactgtaaa atttaggtaa tttatgatat tatatacttg tgtttagcac
    33301 atattttaac tatgtaatta tggaggattt tttatgatat tttttataga cacagccaat
    33361 attgaagaaa taaaagaagc aaatgattta ggtgtaatat gtggtgtaac tactaatcca
    33421 tctctaatag ctaaagaagg tagagatttt atagaggtag ttaaagaaat aagtgaaata
    33481 gtagatggac caataagtgc agaagtaata agtttagagc atgaaggtat gatagaggaa
    33541 gcagaaaaat tatctaagat acataaaaat atagttataa agatacctat gacagcagaa
    33601 ggtctaaaag cggtgaaagt actatcaagt aaaggtataa aaactaatgt aacacttata
    33661 ttctctgctg gacaagctct tttagctgct agagctggag ctacatatgt aagtcctttt
    33721 gttggtagat tggatgatat atcacaaaat ggtcttgatt taattgaaga aatcgttgat
    33781 atatttagtg taaatagtat tgaggctcaa ataatagttg ctagtgttag aaatccaata
    33841 catgttttac aagctgctag aatgggagca gatatagcaa cagttcctct taaagttata
    33901 aaccaaatga ttaagcatcc tttgacagac aaaggaatag atagctttat gaaggattgg
    33961 gaaggtgctt ctttaaaatt ataattataa actacgcttt ataagtatat taaagaggtt
    34021 attatggaaa ttctaagtaa taaggctagg ctattttgcc tagtcttatt ttggtgtata
    34081 atatattgaa acatattatt gaaatagatt aattttttaa gtgaggaggc gaaaaatgga
    34141 taaaatatta agagagatac aaagagaaga taaaaaaaat ccatatactg accaagaact
    34201 tgctgaaatg ttaaatgtag ctaggtctga agtgatatca gtgaggaaaa aaaataatat
    34261 tttagattcg agagaaagaa gaaaaaaaat attaataaaa gatatatcaa aaattgtaag
    34321 tgaaaatcct caaatgtctg aaagaaaaat aactgagata ttaatagaga atggatataa
    34381 tatatcgaga agtgcagttt caaaattatt aaaagaagaa aatttaaatc agtcaaagat
    34441 tgggattaaa gataaagagc cagcatcatc aggaaagtat gtgaaggtga gtaaagttgt
    34501 agaagaagat ggatttgaag aattgatagg tataaaggga agtttgaaag aaaaggtaaa
    34561 tctagctaag tcagcaataa tgtatcctcc taatggcctt catactataa tatatggaga
    34621 aacaggggta ggtaaaagtg aattagctac atgtatgtat aaatatgcta taaaaaacaa
    34681 catcaaagaa gagaacagcc catttatagt gtttaactgt gcagactatg cagaaaatcc
    34741 taatctattg atagctcaac tctttggggt agtaaaaggt gcatatacag gagctgatgc
    34801 aaatagagaa ggtcttgtag aacaagctaa taatggaata ttgtttttag atgaaattca
    34861 tagattgcct gctgctgggc aagaaatctt attttcatta atagatagag gagaatttag
    34921 aaggttagga gaaagtagtt ctaatagaaa ggcaaatgtt ctcataataa gtgctacaac
    34981 agaaaaccca gattctaatt tacttcaaac atttagaaga cgtataccaa tggtaataaa
    35041 tttacctaat atgagtgaaa gaccaaaatc tgaaagatat gaaataataa taaagttttt
    35101 tgaaagagaa gcaaagcgag taaacaagaa ttttataata actaaagaag ttatgtgtgc
    35161 acttatgaat tataagtgta ctggaaatat aggtcagtta aagagtgata tacaagtaac
    35221 ttgtgctaga gcttttagta aatcaatatt ttctagcgat aaggtaatta tagatttaga
    35281 tagtttaagg gattatataa aaagtggata ttatgattgt aattgtaaaa atgaaaagta
    35341 ttctgagttt tcagttgagg atatatatat agatatcagt gaattggtga gtggaaaaaa
    35401 tagaatttta tctgataatg agataagcga gatatataat tatgcagaaa aagagcttaa
    35461 ggttttggaa agtaagtgtt tttcagaaga agagttaaaa aatgcattta tagaaaagtt
    35521 agataagaag tttaatgcta ttaaaaacaa taaaaattta tctgatagaa gaagtcgaat
    35581 agactgggga ggacaattaa aagagtctac attggagata atggataagg taattgtatt
    35641 tattaaggag cagtttaagc atgtaaatca aggattgtac ttggctctag caattcacat
    35701 tgagcatgct ataggtagga taaaagatgg aaaaactata ataaatccga gtttagataa
    35761 aataaaagca tcaatgccaa tggaatatga attgtcaaga tatataatgg gtatagtgga
    35821 agatttgaca caagtaacat ttccagaaga tgaacttgga tatttggctt attatataaa
    35881 taaattttgt tataatgagg aaagtataaa agataaagtt aaagtagtaa tagttacgca
    35941 tggtaaagtt ggaattgaaa tgtctaaagt tgtaaatcat attttaggta tagaatgtac
    36001 actaggtata gaaatagcac ttacagattc accatcagag gggatagagc atgtattaga
    36061 agagcttcaa aagatagaag ctagaaaagg tattctagtt ctaattgata tgggttcttt
    36121 ggtaattctt ggtgatgagg ttgaaaaaag acttggaatt agatgtaaaa ctgtaaacag
    36181 agtagatacg ttattggcaa tggaagcagg aaaacttgca accattgaag gaaaaagttt
    36241 agatggtata atagcagatt taaagaaaaa taagaattat gccatgataa atacaaataa
    36301 atttagttac agaaaaaacg agtatggaaa gaaaaatgta atcattactt tatgtttgag
    36361 tggtgtaggt acagctttaa atttaaaaga gcatatagaa aaacaaatta aggaatatga
    36421 cactttaatt gaggtaaagc cagttgcttt tttaaataat aatttagaag aagagttaaa
    36481 tgatattgaa gctgaatata atattattgc tatctgtgga actatcgata tagattataa
    36541 aaacgtacct tttatttctt ataatgaggt acttggtaaa aatggtatta ataaagtatt
    36601 agagcattta aacagtaaac aaccagtttt aaatattgaa aaccagttga ataatttaat
    36661 acatgaagat ttgattttat acaattttga aggaatttca aaggagtata taattgatac
    36721 tcttgtttca aagcttgaag aaggtggata tgttgactca aagtatatat taagtgtata
    36781 taaaagagaa gcaatgggaa gtgttgtaat ggcctctaag gtagccgtgc cacatggact
    36841 tccagaaaac gttataaagc ctgcaatagc aatcgcaagg ttgaataagc ctatagtgtg
    36901 ggacaataaa tttatggtgg atttggtagt actactggca cttaaagaaa ataataagaa
    36961 agaaatacga agcttatttt caaagattaa tgaccaacat actttagaag ttttattaaa
    37021 tactgaagat aaaaatgaaa taaaagaact tttaagctaa ttattagtac agagaagaaa
    37081 gacaaaaaat ttgctttagt ataaaattta aaactactta attgctaagt agttaattac
    37141 tcgatataag gctagttcta tgaaatttat ttatatgatt ttatagaatt agcttttttc
    37201 ttggtaaata aaatatatga atttatttat gc
//
LOCUS       DAJMZY010000032        34985 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.032, whole genome shotgun sequence.
ACCESSION   DAJMZY010000032 DAJMZY010000000
VERSION     DAJMZY010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 34985)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34985)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34985
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.032"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            complement(19..666)
                     /locus_tag="OE968_001545"
     CDS             complement(19..666)
                     /locus_tag="OE968_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HCP7218828.1"
                     /translation="MKKFLNVLFSICISIVIIVGVINFTVGFKQLYYFDIDYLNISEL
                     SGLSKDDIKLNYDYLIDYNLNKNVSEFKLPTLKSSPQGKIHFEEVRNIFQNINKLAKL
                     LLVVSLVGIILSVKNKNIKILKTTSITLIIMPLLLTVPILLNFEKSFIIFHKLLFRND
                     YWIFNPDLDPVINILPEEFFFHSGMMILILILLVSIVLFVMYKLCKSLSIKIFQC"
     gene            complement(695..2245)
                     /locus_tag="OE968_001546"
     CDS             complement(695..2245)
                     /locus_tag="OE968_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018592108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HCP7218829.1"
                     /translation="MLVVENVSHGFGARTILENVSFRLRKGEHIALVGANGEGKSSFL
                     NIITKKLMPDAGNIKWSSRATVGYLDQHTVLSKGKTIREVLREAFKHMFDLEQEMIAM
                     YDKMGEASDDEMSKLLEETAEIQTILENSGFYMIDAKIQEVANGLGLGEIGLDKDVTD
                     LSGGQRTKVLLTKLLLENPTILILDEPTNYLDEEHITWLTKYLQEYENSFVLVSHDIE
                     FINNTCNVIYHMENGELNRYKGNYDEFVRLNDIKKRQEEQAYDKQVEERKRLEDFVAR
                     NKARVATRGMANSRQKQLDKMEILERPKEKIKPTFAFKDARAASKIIFETENLVLGYD
                     EALTKPLNFHLERGKKIALKGMNGIGKSTLLKTLLGIIKPFEGNVKLGDYLEVGYFEQ
                     ESSRENSNTPMDEVWSEFPGLTNFEVRQALAKCGLTNEHITSQMRVLSGGEAAKVRLC
                     KVMLKNINFLVLDEPTNHLDVEAKDELKKAIKEFKGTVLLVCHEPEFYSEIVDDVWNI
                     EDFTTKIV"
     gene            complement(2447..3331)
                     /locus_tag="OE968_001547"
     CDS             complement(2447..3331)
                     /locus_tag="OE968_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HCP7218830.1"
                     /translation="MKKYRLLVTCIIAMGIIIIGTSNPVSNFYKTTNLISSGNITNEK
                     ANKDENSNKNNKDKNEDKSNSKSNKDKSSEDKSSDNKNEIQKNKKLLICIDPGHQGKG
                     DSNLEPVAPGSSSKKARVSSGTEGIATKKPEYVLNLEASLVLKSILESKGYNVIMTRE
                     THDVNISNSERAILANDKKADMVVRIHADSLNNSSKTGASILIPEKDGKYTAPIYEES
                     NKCAEFIKQNMEQSGIQINGIVQRGDLTGFNWSKVPAVLVEMGFMSNYNEDQMMSNPD
                     YQRKMMQCIADGLDAYFK"
     gene            3559..4572
                     /locus_tag="OE968_001548"
     CDS             3559..4572
                     /locus_tag="OE968_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S55"
                     /protein_id="HCP7218831.1"
                     /translation="MQLKNFHFKNNTLSKKTNLAKSKFTIVLTFLFLFLLYFFSNNLI
                     YAQNLQKNEPEYLIPIGNVLQIDAELKNIIVRNPGEASPFRLGDAIVKVNNAEVDGYS
                     DFANTLNALPEEKQVSILLNRGGQLITMKTTKHILEKISFNNLLSGFATLTYINPDTS
                     EFGAVGHPISVGNARKIPIKTGSISTTKHLNIEKSYKGSVGCINAKRENIIGSFTENT
                     DFGIRGQINNFDISKLKKYKVASLDEVKLGKAQIILQDNFNKCKKYNIEIIDIENQKH
                     PESKSFKIKITDKKLLAQTGGIVQGMSGTPIVQDNKIIGAVSHAIENDPAVGYGVFIK
                     WML"
     gene            complement(4788..5486)
                     /gene="yunB"
                     /locus_tag="OE968_001549"
     CDS             complement(4788..5486)
                     /gene="yunB"
                     /locus_tag="OE968_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein YunB"
                     /protein_id="HCP7218832.1"
                     /translation="MNRIVDRKTKNEFRKIIAIFLVILFLSVFIGSFIYIDKTLRPTI
                     TVLAETKALELANRSINKAVAEMVEGKINYEDLMDIQLDNNGKITMIQANTIMMNEIA
                     SAIALEIQDELKKDKTASSYIPIGTALGSPILAKYGPKLEVSIEPIGTVSVNFKTEFE
                     SSGINQTRHRIYLEAQTQVKVVIPLITSTKQIKAQIPICETIIVGDVPESYVNIPEKN
                     LGNVLPNTGKNTNK"
     gene            5700..8393
                     /locus_tag="OE968_001550"
     CDS             5700..8393
                     /locus_tag="OE968_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase domain-containing protein"
                     /protein_id="HCP7218833.1"
                     /translation="MNNDNDKNGNKIRRKKVSSSGNTNKPINRTSANKTRSTKNKKKS
                     KKSDKFKKLRVFGIVFLVLLVVGTAGTAGLVFASLRDVTPVTEAVLDKQTNQTTTIKY
                     ANGKTLSTAPSVNKKTPVPLDKISPYLQHAVIAIEDERFYEHKGVDIKGLFRSVLKTL
                     TGTKQGGSTIPMQVSKMLLTTEQQTIPRKIKDIYYAHEMSKTVSKDKILETYLNNFFV
                     GRGLAGAEAGARGYFDKSAADLTLAESALLAGSTKNPSRFSAYKTSKLEGNETKEDLE
                     NKLLFFVNTTDDDLDDPTQVDFDMIEKIKSWELISNDTYRQLKAGTLVVRKAVSNPEA
                     KKRQEIVLKKMLELKYIKQSEYDEAIKAKIEIKLPQSSDKVSSSVEDLIESEVINALM
                     EQGHTNDEAQNLFYNGGLIVNTTIDPKMQDALEEEFDRNSNFPGHMVGPDGVSQPQAA
                     MVILDYKNGEIRALAGGRNISGRKTLNRATNPHQPGSSIKPLAIYTPAIDTLKITQAT
                     ALSDSRGGYKFKENNEWNPRTTTAGHGSMSLRKALAKSSNTIAVKTAEMLGDSYDECV
                     DIMMDYLKNFGITTLKNNHSGSSEASDRKFPSLTLGGMANGITPLQMAAAYGTLANHG
                     IYVEPSIFTTITTFDGQLLVKNAPEEHKVVDPEVAYVVTDMLESVITEGTGGVATLPK
                     GMPVAGKTGTTNSAYDAWFVGYTPYYVGATYIGDDAGRKDDSGNTIKRREVPHGSTST
                     AKLWEKIMEKIHANLTVTEFEVPKNVYFTKINLEDGGKQSSGSKAAFIEGTAPTKVSS
                     QPSSEDTKKPDNNQPEENNNNNNNTGDNGGGSTPPDNGGNNGGGSTTPPDNGGNNGGG
                     STTPPDNGGNNGGGSTTPPDNGGNNGGGSTTPPDGGGTPAT"
     gene            complement(8667..9602)
                     /locus_tag="OE968_001551"
     CDS             complement(8667..9602)
                     /locus_tag="OE968_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1177 domain-containing protein"
                     /protein_id="HCP7218834.1"
                     /translation="MILKQVIEVYDILDKANANGEEVKTYLQGYGEVDVTVKELSSSK
                     GSTDLVKLTIPGKNGKLKGGDAPTLGILGRLGGIGARPEVIGFVSDGDGALVAIAVAA
                     KLLDMQRKGDILDGDVVISTHICPDAPTKEHYPTPFMDSPIDMMTMNENEVDSSCDAI
                     LSIDTTKGNRVINTRGFAISPTVKEGYILKTSDNLLDIMQTVTGKSPFVFPLSIQDIT
                     PYGNNLYHLNSILQPAVATDAPIVGVAITTEMPVAGCATGATNFSDLDSAGRFAIEVA
                     KLFGRNKCDFYDKEEWEMLIKRYGKLNRFQTFGIQ"
     gene            complement(9646..10818)
                     /locus_tag="OE968_001552"
     CDS             complement(9646..10818)
                     /locus_tag="OE968_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HCP7218835.1"
                     /translation="MECFKEVVNMNELKAKIKEEIKLLSEEKKTSFEKVSDYLFSNPE
                     LAFEEYKSQKALCDLLEENEFNVTKGVGGLETSFEAVYSNGTNGKTVAFLAEYDALPG
                     MGHACGHNIIGTSSVGAGIILKEIMKKHNIEGTVKVFGTPAEERVGGKITMIKEGVFN
                     NVDAALILHPSDASMPDDISFAQVNLKFDFTGKASHAAAFPWEGKSALSGVIALFNSV
                     NSMRLHLKDYARVHGIITDGGSIHNIIPEKSTAIFNVRALSIEYLNEICEMLKNCAKG
                     AAISTGTNVEIVQLDEIYKEIKNDSELVNIVRQNFEVLGEDYVERDLSQGIGSTDTGN
                     LTHEIPAIQAYIKLKENTATHTDEFAVAAGGEEGRVALIKAIKVLAMCGVDILYSK"
     gene            complement(10805..11269)
                     /locus_tag="OE968_001553"
     CDS             complement(10805..11269)
                     /locus_tag="OE968_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218836.1"
                     /translation="MEKTFKTIMEQIKIVLFIYIIICFGQMIALKTQAQDLLIGSVSG
                     FLLVIIAIIIKNFVKKPNLPGFAWATLVAFVLSLPISPVGDIIATNVGKINFMSTVTP
                     LLAFAGISVGNQLDILKTLSWKLVVISFIVMTSTYFGSAFISQTVLRLNGML"
     gene            complement(11284..12126)
                     /locus_tag="OE968_001554"
     CDS             complement(11284..12126)
                     /locus_tag="OE968_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3100 domain-containing protein"
                     /protein_id="HCP7218837.1"
                     /translation="MKEKAGIRNAIIAAFIITILAELIGPISFKVMGINVTLLSILWA
                     IFIGMAVSPHLLGRVIPALKKFIGDNEINVSPYLLSLTLYPLGIMFGINAGPKVGILL
                     QAGPALLLQEFGHMGTMLIALPVGVALGLGRSALGGTFSLCRDTALGIIGDKYGLNSP
                     EGIGTLGTYISGSIFGTLLFSFLAPVGVLLGFHPYALAMASGMGSGSMMGAATASLMN
                     TVPQMSEQILAYSATSGLITAVTGIYIELFLSLPVANYYYSKVAPVIERFRGRKTRRT
                     SNKL"
     gene            complement(12501..13517)
                     /locus_tag="OE968_001555"
     CDS             complement(12501..13517)
                     /locus_tag="OE968_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCP7218838.1"
                     /translation="MVTIKDIARNLGISYSTVSRCLNNNPNVSEKTKKKVVEEANRLG
                     FHFNVNARNLAKKETNRIGVIFSNNFNHQDTRKFFSDIMDSSINSIETNKYDFIIQPN
                     NNISGDSNVYKMVNGQMVDGLVIVSQSIKKEEYDFLKDNNFPHVFIYFKPSFIGEVDN
                     FFWDDNVYGGYIATKHLIDHGHKDIITVTSDDKSSKMHEDRTKGYLNAMEEANLKTEV
                     IKSKMDFESQVEFLEKYIDKIKKASAIFVQQDVPAISIIQELKTTYGINVPEDISIIG
                     YNNIELISYFRSHLSTIDDPREQVIKNGVDSLVNIINKKSTEHIPRKLYPRLIIRNSV
                     KRIK"
     gene            complement(13700..14062)
                     /gene="spoVAE"
                     /locus_tag="OE968_001556"
     CDS             complement(13700..14062)
                     /gene="spoVAE"
                     /locus_tag="OE968_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein AE"
                     /protein_id="HCP7218839.1"
                     /translation="MLMDYVRVFIVGGIICLIAQVMMDYFKMQTPYVMVTYVTTGVVL
                     TFLGLYEPLVKFAAAGATVPIIGFGYSLATGVIKSIQSDGFLGIFLGGTTATAGGIAA
                     AIFFGYIMSVVFTPKAKP"
     gene            complement(14076..15089)
                     /gene="spoVAD"
                     /locus_tag="OE968_001557"
     CDS             complement(14076..15089)
                     /gene="spoVAD"
                     /locus_tag="OE968_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein AD"
                     /protein_id="HCP7218840.1"
                     /translation="MKNKRIGKRTVKLENKPTIISTGTIVGPKEGEGPLKDYFDMIMT
                     DDLYGEKTWELAESKMVETASQQAIQKAGKKLSDVNYMLGGDLINQIVPASFAARELA
                     IPFLGIYGACSTMAEGLCIGSMLIDGGFADLVLSGTSSHYCTAERQFRFPLELGNQKP
                     MTAQWTVTGAGSVLLAPNGDGPKVKYVTVGKVIDEGIDDGNNMGPAMAPAAIDTIYSY
                     FEDTNDDPNSFDIIATGDLGTLGKQIAEDFLKEKGVDISKVYTDCGIEMFNLKEQDVH
                     CGGSGCGCSATVFAGYIYDKLRKKEFNKVMLVSTGALLSPTSTLQKQTIPCVAHAVVI
                     VNE"
     gene            complement(15256..15693)
                     /gene="spoVAC"
                     /locus_tag="OE968_001558"
     CDS             complement(15256..15693)
                     /gene="spoVAC"
                     /locus_tag="OE968_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein AC"
                     /protein_id="HCP7218841.1"
                     /translation="MDKNYKKYVDQISPKPTYLKNYTLAFIVGGIICMIGQAINDLYM
                     KVGGLDKLGASSATSITLIFIGAFLTGLGVYDLIGKRAGAGSIIPITGFANSIVSPAM
                     EYKREGYVLGVGANLFKIAGPVLVYGIGSSILCGIIYYIFKMF"
     gene            complement(15973..16737)
                     /gene="sigF"
                     /locus_tag="OE968_001559"
     CDS             complement(15973..16737)
                     /gene="sigF"
                     /locus_tag="OE968_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigF"
                     /protein_id="HCP7218842.1"
                     /translation="MEVTVAREEKKPLLSHEETLELIEKVQNGDEEAKEILISSNLGL
                     VRSVVSRFLNIGYDREDLFQLGSIGLIKSIYKFDPKFNVKFSTYAVPMILGEIKRYLR
                     DDGMIKVSRSLKQIAVKAKMESEALTKKLGREPSIEELAKAIDVEKEDLVMAMEANFN
                     VEYLQGVIHEEEGSPICLIDKISMKGESEEEKVVDNILLKDILGRLDKRERQIIVLRY
                     FEDMTQSEIGEMLNISQVQVSRIEKKVLSKLKEYIS"
     gene            complement(16760..17188)
                     /locus_tag="OE968_001560"
     CDS             complement(16760..17188)
                     /locus_tag="OE968_001560"
                     /EC_number="2.7.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-sigma F factor"
                     /protein_id="HCP7218843.1"
                     /translation="MNNIMEVKFSAISENESLARVIVASFAAKLDPTVDELVDIKTAV
                     SEAVTNAIIHGYEEDSSKFVFLRCEIEGNTIKIIVEDEGYGIENVEKAMEPLYTSKPE
                     LDRSGMGFTVMKSFMDDVEVSSVKDNGTRIEMTKKINVPK"
     gene            complement(17202..17537)
                     /gene="spoIIAA"
                     /locus_tag="OE968_001561"
     CDS             complement(17202..17537)
                     /gene="spoIIAA"
                     /locus_tag="OE968_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-sigma F factor antagonist"
                     /protein_id="HCP7218844.1"
                     /translation="MVNYSLEHKNLYIEFMCSELDHHVANEIREEIDNLLSVNQVKNV
                     VFNFENINFMDSSGIGVIIGRYKKISNEGGRVSVINISSRVKKIFDLSGLNKIIGIYD
                     TYEEALSSL"
     gene            complement(17625..20063)
                     /locus_tag="OE968_001562"
     CDS             complement(17625..20063)
                     /locus_tag="OE968_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HCP7218845.1"
                     /translation="MDIIKKLSHGCTLDCHDCCKFNVYTKGNNVVKIEGDKNHPYTKG
                     FICKKGMAHLDRLNHKDRIKTPMLKVDGVWKEISFDKAIEIMAEKLTYYKEKYTSKSV
                     MHYDQYGSGSVLKYIGDIFFNFYGGVSRHKGGPCWSAGMHAQKYDFGVAKSHAIEDML
                     NSKSIFVWGKNPAYTTIHTMQIIKKAKEKGIKIVVIDPIYTKTAQIADKYVQVNPGTD
                     GALAIAMAKIIVEDKLYDEEYINSYVIGFEEYKKYLSSLELSFLIDECGVKENDIREL
                     VDLYTNKYSSINVGYGLQKYKNGGNTIRAIDALGAITGQIGFSGGGVNYANKVYPSVI
                     NSDPYNSQSYGEDREFYVSNISKFIEESLKNTSNKVNYASDELDMALHKVNYISDELD
                     TTSNKVNYVSDELDMALHKVNYVSDELDTTSNKVNYVSDELDMALHKVNGVSDELDMA
                     LHKVNCVSDELDMTSNKVNYVSDELDMTSNKVNYVLDELDITSNKTDYISNELYNLSN
                     KSIKDNIPIKMAVITKSNMLNQLPDLVELERVFSKIEFKVCFDMFITDTVTLCDMFIP
                     CTNTLESEDIIYSSMTNPYITYNERAVKPAHKLMDEYYFFMELAKKMGLNDYPFVEKR
                     TYLEKVIEPLKRFDKNLDIEKLKNNYFTIHNPVAWEDKKFETPSGKYELYSESIKNLG
                     ISPTPVYISNKYKEIEDKNISFRLLTNHHADTLFSQHFMDKKSIAQAYINQRMAKKVG
                     IEEKDIVILRSKKAKINVQINIDDGVGNYIVKMYVGWWKKHGNPNSLTDTGISDFGGQ
                     VTYNESMVEIIRQN"
     gene            complement(20412..21185)
                     /gene="srlD"
                     /locus_tag="OE968_001563"
     CDS             complement(20412..21185)
                     /gene="srlD"
                     /locus_tag="OE968_001563"
                     /EC_number="1.1.1.140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sorbitol-6-phosphate dehydrogenase"
                     /protein_id="HCP7218846.1"
                     /translation="MRKVALVVGGGRSLGEYLSKHLAKVGYDVAIADLNEDNAKKVAE
                     EIKTEFGCKSVGYSCNAIDERQVISTVKAIENDFDRIDLLVYNAGVAVSKKITDFGYK
                     DFKFIVDVNLNGYFLFAREVSKVMIAKGIEGRIIQINSKSGRVGSKHNSGYSAGKFAG
                     VGLTQSLALDLAEHKITVNALMLGNLLDSDMFESLIPQYAVKLGIPESEVKQVYIDKV
                     PLKRGCRFIDVANMLTFYASKEAEYCTGQSINITGGQVM"
     gene            complement(21286..21651)
                     /locus_tag="OE968_001564"
     CDS             complement(21286..21651)
                     /locus_tag="OE968_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HCP7218847.1"
                     /translation="MELIYSTQINKIGDNANEFLQHNMFVTFKDNAPQELENYCYIHS
                     ENNLVKEILTDDVLSINNVDYKITSVGELVNQNLSELGHITFKFTGEKDGAIGGTLYL
                     EEKEIAPIGVGTILKIIRK"
     gene            complement(21692..22651)
                     /locus_tag="OE968_001565"
                     /pseudo
     CDS             complement(21692..22651)
                     /locus_tag="OE968_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006565779.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
     gene            complement(22715..23275)
                     /gene="srlA"
                     /locus_tag="OE968_001566"
     CDS             complement(22715..23275)
                     /gene="srlA"
                     /locus_tag="OE968_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418408.1"
                     /note="catalyzes the phosphorylation of incoming sugar
                     substrates along with their translocation across the cell
                     membrane; the IIC domain forms the PTS system
                     translocation channel and contains the specific
                     substrate-binding site; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HCP7218848.1"
                     /translation="MTQFFQVLASGADSFMNLFRAGGQQFVGFVTDIVPLLVALLVTM
                     NAIINFIGTDRVERLAKKCSANIFTRYLILPVLGTFVFANPMTLSLGRFLPEKFKPSY
                     FAAASFSCHTMNGLFPHINPGELFIYLGIANGITTLGFSTADLAVRYLLVGIVANFIK
                     GVVTDYTTKFVEKQQGIALNSDIKIG"
     gene            complement(23304..23738)
                     /locus_tag="OE968_001567"
     CDS             complement(23304..23738)
                     /locus_tag="OE968_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator GutM"
                     /protein_id="HCP7218849.1"
                     /translation="MDPVIFIIASLITVYLLNIFLGYLQLKDFNKNYIELKRKGRVAI
                     GRKKGRISSGTIVLILINDDGVIVETRKMQGVTVLARVKSFEGLVGKSLEYIEKSDLT
                     VYNKLLKKAILDAVKQYITFEKNKCEDTNNLSTDEECRMEVV"
     gene            complement(23743..25728)
                     /locus_tag="OE968_001568"
     CDS             complement(23743..25728)
                     /locus_tag="OE968_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HCP7218850.1"
                     /translation="MSMTYMDPRVFLILEMVLEEDTNTLEQFSNVLGVSTRTIRNYIN
                     QINRELKGGIAKIVKNEKGTYSIRIEDESKLIEIVNFNRGKLSNFINLNSPDERINYV
                     LDILTMTNNPITIDDLAEEICIGRTTLIKDLKKADRILAEYDLELKRKPNIGMILVGE
                     EMDIRLLILDRLYENYIDVLENVNQINLVKDYDIECLRDELKKLFKKEELYITEQVLR
                     DVERYIIMSVLRNLNGYKFEKIDKRFEVIRCSDEYTLGLKLKALLEKIFNIVLNEKET
                     IFLTMPLIGRKAPSTKLALSSIKINDSVKEVVDEVTSFLLETSGIDFKEDKKLIENLE
                     YHLYFALNRMRFNIRVKNPLLQEIKERYTFPYSVAKIAAMIIEEKFDLKICDHEIGYI
                     ALHFGSYFEKNSRKVLNVNRVAVVCGTGLGTAQLIRIKIGKILGESVEVNTFSDIEAK
                     ANLDLLKYYDLVFTTVDFKTDLDVPIFRVNALFNEESIKKEIENAILLKNSINLKSIK
                     KIEKNIPFIGKLIEEDKFFILNKSTFMENLEDMLEKLVHKGIIDIEFKKKVLKREKKS
                     STALDNYIALPHSVNTNGENLYLAFGILEKPVIWDTKEIRIIILMIIPDKNVDSTDLI
                     IKSYEEVLEVGRDKKMVEELAKVKSFDEFYKIITKRR"
     gene            complement(26003..27616)
                     /locus_tag="OE968_001569"
     CDS             complement(26003..27616)
                     /locus_tag="OE968_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HCP7218851.1"
                     /translation="MNITKFEDLPISEGIKKAIAEMGFEEPSPIQAQSIPAILSGKDV
                     IGQAQTGTGKTAAFSIPILETIDPNNRSLQAVVLCPTRELAIQVSTEIRKLAKYSHGI
                     KTLPIYGGQPIDRQIKSLKSGVQVVIGTPGRTIDHINRKTLKMDNVKMIILDEADEML
                     DMGFREDIEMILSKIPEERQTTFFSATMPRGILELTKRYQKDPEHIKVVRKELTVSNT
                     KQYYIETRSSNKLEVLCRLVDVYDPKLSVVFCNTKRKADELVGDLQARGYFADALHGD
                     LKQTQRDIVMDKFRNGTIDILVATDVAARGIDVDDVECVFNYDLPQDEEYYVHRIGRT
                     GRAGREGMSFTFVFGKEMRKMKDIERYTKSKLIKHNIPTITDVEEKKVGTFFAQVKQT
                     IEEGHLTKQLQWLEGFCNDEDYAMVDIAAALVKLSLGEEMKEEIIEEKPRRERGDRKG
                     GTGAKDGMIRLFINIGRNQRVQAKDIVGAIAGEVGIPGKVVGTIDIYDKYTFVEIPKK
                     DAKTVIEKMKDIKIKGNKINIEKANKKKK"
     gene            complement(27707..28768)
                     /locus_tag="OE968_001570"
     CDS             complement(27707..28768)
                     /locus_tag="OE968_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium/sodium antiporter"
                     /protein_id="HCP7218852.1"
                     /translation="MEKRKSIHLHKLNIYLIGGGDRLFITVVLFLVGFLLITKGADIF
                     INCTVEIGKKTNISEIILGATIVSFATTLPEFTVSLLASIDGHTTMSLGNAVGSIICN
                     TGLALGLVVFISPFNVDKKMFFSKSLLLIVSVIVLILLSLDGVITRGDSLLLIIILIF
                     YMVNNYRSVVGKSDTKNRNIKNNTIKDISTKKGKNYRGFSVLEIVKILLLFATGLIMM
                     IIGSQILIESGVIIASFLNIPQGIVSLTIIALGTSLPEIVSSITAIRKNHHEISVGNI
                     LGANILNIVSVIAVSAIPNNIPILSQNRQLDIPFMILLLLIVIIPTLKSNRLSRIQGI
                     LMLFTYFLYISILYFMYII"
     gene            29061..31292
                     /gene="pflB"
                     /locus_tag="OE968_001571"
     CDS             29061..31292
                     /gene="pflB"
                     /locus_tag="OE968_001571"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HCP7218853.1"
                     /translation="MNAWQGFKTGRWTKEINVREFIQLNYSPYEGNDSFLAGATENTK
                     KLWDEAMVLFKKERENGGTLDVDTKTVSGIAAYAPGYLDKELETIVGLQTDAPLKRAV
                     MPYGGIKMVENSCEAFGYELDPEIKDIFTKYRKTHNQGVFDVYTPEMRAARKSGIITG
                     LPDAYGRGRIIGDYRRVALYGVDALIEDKNEQKKSLEVSCMDEEVIRLREEITEQISA
                     LNELKKMAESYGFDISKPATNSKEAVQWLYFGYLGAVKDQNGAAMSLGRTSTFLDIYF
                     ERDLKAGIVTEEELQEYMDHFVMKLRMVKFLRTPDYNNLFSGDPTWVTECIGGMGIDG
                     RTLVTKNSFRMLNTLYTLGPSPEPNLTVLWSTKLPQGFKDFCSKVSIDTSSVQYENDD
                     LMRAYWGDDYGIACCVSAMRIGKQMQFFGARVNLAKTLLYAINGGVDEKSGVQVGPRF
                     EPITSEYLDYDEVMSKFEPFTDWLATLYVNTLNVIHYMHDKYSYEALEMALHDRDIFR
                     TMACGMAGLSVCADSLSAIKHAKVKTIRNEQGIAVDFEIEGDYPKYGNNDDRVDSIAV
                     ELVESFMNKIRKNKTYRNSYPTQSILTITSNVVYGKKTGNTPDGRRAGAPFAPGANPM
                     HGRDTNGALASLSSVAKLPYEHAQDGISNTFSIVPAALGKDMTERINNLSAMMDGYFA
                     QNAHHLNVNVFDRATLEDAMEHPEEYPQLTIRVSGYAVNFIKLTKEQQLDVINRTFHG
                     KMA"
     gene            31452..32186
                     /gene="pflA"
                     /locus_tag="OE968_001572"
     CDS             31452..32186
                     /gene="pflA"
                     /locus_tag="OE968_001572"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HCP7218854.1"
                     /translation="MIKGKIHSIETFGTVDGPGIRYILFFQGCPLRCKYCHNRDTWDI
                     KSGKEYTVDEIITDALKYTSFMKFSGGGITASGGESTLQPEFLSELFKKAKENDIHTC
                     LDTSGFVDIETIDPVLDNTDLVLLDLKHMVEEKSIDLTGVGMDKALKLARHLESRNIP
                     VWIRHVLVPGITDDIDNLEKLGQFVATLKNVERFELLPYHSMGIHKWESLGIDYELKD
                     VPDATKEDVQKASEIISKFGVKVYNS"
     gene            complement(32308..33978)
                     /locus_tag="OE968_001573"
     CDS             complement(32308..33978)
                     /locus_tag="OE968_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF and EAL domain-containing protein"
                     /protein_id="HCP7218855.1"
                     /translation="MREESNSLSLDHIEIFFELLSQSTEDYIFFWDINRNKFKISSAI
                     FDEFNLSKEIESDLVNCWSKIVYPDDVQIWKDDIQELLHGKKGEHNLEYRLINKYKEI
                     VWISCRGKVYVSDDPKTIFLVGRIKNIGEKNKFDSITGTWNREQFEHKMNYLIKEKIY
                     KNGAMFIMDIDNFKNINEKYGHSYGDKVLRAIATEVLEYLPKDVRLYRLDGDEFAFFY
                     PMCTKETIEKIYEKIQMYTNTQHEIESSKYYCTVTAGVAMYPEDGDNYLDLFKHADIA
                     LDIAKISGKNRIKFFSQELYENKLKVISMQQKLRECVENNFNDFELFFQPQVNAVTKE
                     VIGAEVLLRWHSSTYGEVSPVEFIPILEQSNLIIPVGKWIIKEAVKQCKEWHKINPDF
                     KISVNVSYIQLKEDFFRDFIVECLVEYQLRPEFLILELTENCWIPDINLLNDKFISLK
                     GIGVYIAIDDFGTGYSSLNYLKELSVNIIKIERSFVKNITYNSYEYTFLEYIIKLAHI
                     INLKVCVEGIESYEEYDIVKSLGVDIIQGFLFGRPVSASEFYKFQLSK"
BASE COUNT        11555 a         5965 c         4128 g        13337 t
ORIGIN      
        1 ataaaaatat ccctctattt aacattgaaa tatttttatt gataaagatt tacataattt
       61 atacattaca aacagtacta tacttactaa caaaattaat attaaaatca tcattccaga
      121 gtgaaaaaaa aattcctctg gcaatatatt tataactggg tctaaatcgg gattaaatat
      181 ccaataatca tttctaaata ataatttatg aaaaataata aatgactttt caaaatttaa
      241 taaaattgga actgttaata ataatggcat aattataagt gttattgatg tagtttttaa
      301 gatttttata tttttatttt ttacactcaa tataattcct actaaagaaa ctaccaataa
      361 taatttagct aatttattta tattttgaaa tatattcctg acttcttcaa aatgtatctt
      421 cccttgtgga gaagatttta atgttggtaa tttgaactca gacacattct tatttaagtt
      481 ataatcaatt agataatcgt agttcaattt tatatcatct ttagataaac cagataactc
      541 tgatatattt aagtaatcaa tgtcaaaata ataaagttgt ttaaatccaa cagtaaaatt
      601 aataacacct actattataa caatactaat acaaattgaa aaaagtacat ttagaaactt
      661 tttcatgaaa tccccccagc aataagttaa atcactacac gattttagtt gtaaaatctt
      721 ctatattcca tacatcatca acaatttctg aataaaattc tggctcatga catactaaaa
      781 gaactgttcc cttaaactct ttgatagcct tcttcaattc atcttttgcc tcaacatcta
      841 aatgatttgt aggctcatct aatactaaga aatttatatt ttttaacatt actttgcaaa
      901 gtctaacctt agcagcttct ccaccactta atactctcat ttgactcgtt atatgttcat
      961 ttgtaagtcc acattttgca agagcctgtc taacttcaaa gtttgtaagc cctggaaatt
     1021 cactccaaac ttcatccata ggtgtattac tattttctct tgaactctct tgttcaaaat
     1081 atccaacttc caaatagtca cctaatttaa catttccttc aaatggtttt attattccaa
     1141 gtaaagtttt taatagagta gattttccaa taccattcat tccttttaag gcaatctttt
     1201 ttcctctttc taaatggaaa ttaagtggtt ttgtcaatgc ttcatcatac cctaaaacta
     1261 aattttctgt ttcaaaaatt attttactag ctgctctagc atctttaaaa gcaaaagtag
     1321 gttttatttt ttcttttggt ctttctaata tttccatctt atcaagttgc ttttgtctac
     1381 tgttagccat tcctctagtt gctactctag ctttatttct agctacaaaa tcctctagtc
     1441 tttttctttc ttcaacttgt ttatcataag cttgttcttc ttgacgtttc tttatatcat
     1501 taagtcttac aaattcatca taatttcctt tatatctatt taactctcca ttttccatat
     1561 gatatattac attacatgta ttatttataa attcaatatc atgagaaact aagacaaaac
     1621 tattctcata ctcttgaagg tacttagtaa gccatgttat atgctcttcg tctaaatagt
     1681 ttgtaggctc atccaatata agaatagttg gattttcaag tagaagttta gtaagaagta
     1741 cttttgttct ttgccctcca cttaagtcag ttacatcttt atcaagacca atttctccaa
     1801 gaccaagacc atttgcaact tcttgtatct ttgcatctat catataaaaa ccactatttt
     1861 caagtatagt ttgtatctct gctgtttctt caagaagctt actcatttca tcatcactag
     1921 cttctcccat tttgtcatac atagcaatca tttcttgctc taagtcaaac atatgcttaa
     1981 aagcctctct aagcacttct cttatagttt ttcccttgct taataccgta tgttggtcta
     2041 agtaacctac tgtagctctt gaagaccatt ttatatttcc agcatctggc ataagcttct
     2101 ttgttattat atttaaaaaa ctcgattttc cttctccatt agcaccaact agtgcaatat
     2161 gttcaccttt tctaagtcta aaggatacat tttctaatat tgttctcgca ccaaatccat
     2221 gactcacatt ttctactact agcatttcaa cacctctcaa aaaaatttta cacattctat
     2281 actataatat attcttttta aacttaaatc aagtattccc aatattttta gttatattta
     2341 cgacaattta acctaaaata aacttcttct ttgtgttatg tacaataaaa aatagagata
     2401 aaaattagga aaataatacc aacctaactt tttctctatt catatcttat ttaaaatacg
     2461 catccaatcc atcagctata cactgcatca tttttctttg gtagtctgga tttgacatca
     2521 tttggtcttc attatagtta ctcataaatc ccatttctac taatacagct ggtacttttg
     2581 accagttgaa tccagtcaaa tcacctcttt gaacgattcc attgatttgt atacctgatt
     2641 gttccatatt ctgtttgata aattcagcac atttattact ttcttcatat ataggagctg
     2701 tatattttcc atctttttca ggaatcaata tagatgctcc agtttttgaa gaattattta
     2761 aactatctgc atgtattctt acaaccatat ctgctttttt gtcattagca agtattgctc
     2821 tttctgaatt acttatattt acatcatgtg tctctctagt cattattaca ttataacctt
     2881 tagattctaa tatactcttt aaaacaagag atgcttctaa gtttaaaaca tattctggct
     2941 tttttgtagc aataccctct gttcctgaag atactcttgc ttttttagag gaagaacctg
     3001 gagctactgg ttctaaattg ctatctcctt ttccttgatg ccctgggtct atacaaatta
     3061 aaagtttttt atttttttga atttcatttt tattatctga cgatttgtcc tctgatgact
     3121 tatctttatt acttttagaa ttagatttgt cttcattttt atctttatta tttttgtttg
     3181 aattttcatc tttatttgct ttttcatttg tgatatttcc tgaactaatc aaatttgtag
     3241 tcttgtaaaa attgctaact ggatttgatg ttcctataat tatgattccc atggcaatta
     3301 tacaagtaac taacaatcta tattttttca ttttttgctc ctttcttatg ctagacagtt
     3361 attgtttatt tttatttata tgaatatgta tttattttat catatacact atttatttta
     3421 tttattttta tgaaaactaa ggtgttattg agctagtttt ccaagcatca aaacatgatt
     3481 cttgcacaac ataatataga agcagcaaga aaacttcaat tctattatta aaataattta
     3541 ataagaaaga ggtgttttat gcaacttaaa aattttcatt ttaaaaataa tactttaagt
     3601 aaaaaaacca acttagctaa gtcaaaattt acaattgttt taacattttt atttttattt
     3661 ttattatatt ttttctcaaa taatttaatt tatgcacaaa atttacaaaa aaatgaacct
     3721 gaatatttaa taccaattgg aaacgtactt caaattgacg cagaattaaa aaatatcata
     3781 gttagaaatc ctggagaagc atctccattt agattgggtg atgctatagt aaaggtaaat
     3841 aatgctgaag ttgatggata tagtgacttt gccaatacct taaatgcttt accagaagaa
     3901 aaacaagtat ctattttatt aaatagaggt ggacaactta taacaatgaa aactaccaaa
     3961 cacatattag aaaaaattag ttttaacaat ttactttctg gatttgctac tttaacgtat
     4021 atcaatccag atacatcaga gtttggagct gtaggtcatc caataagtgt tggtaatgca
     4081 agaaaaatac ctattaaaac aggttcaatt tctacaacta agcaccttaa tatagaaaaa
     4141 tcttataaag gtagtgttgg atgtataaat gcaaaacgag aaaatattat tggtagcttt
     4201 acagaaaata ctgattttgg aataagaggt caaattaata actttgatat ttccaagtta
     4261 aaaaaatata aagtagcatc tttagatgaa gttaaattag gaaaagcaca aataatttta
     4321 caagataact ttaataagtg taaaaaatat aatattgaaa ttatagatat agaaaaccaa
     4381 aaacatccag aaagtaaaag ttttaaaatt aaaattacag ataaaaagct tttagctcaa
     4441 actggtggta ttgtacaagg tatgagtggt actccaatag ttcaagataa taaaataatc
     4501 ggagcagtgt cacatgcaat tgaaaacgac ccagctgtag gttatggtgt atttattaaa
     4561 tggatgttgt aaataatata aataaataaa taagttttaa gatgttatta agttattaat
     4621 aatatatttg gtctaaaggt acttttattt aacctacaga ccaaatatat tagatatttt
     4681 acatagtata aaatataaat ttttattaaa attatattaa tattatttcc aaaaatttta
     4741 tttataaact attattttga atttatttaa aaatatacaa ctttatatta cttgttggta
     4801 ttctttccag tgttaggtaa aacatttcct agattttttt ctggaatatt tacataactt
     4861 tctggaacat cacctactat tatagtttca caaataggta tttgagcttt aatttgtttt
     4921 gttgaagtta taagtggtat tactacttta acttgtgttt gagcttctaa atatattcta
     4981 tgtctagttt gatttatacc tgaagactca aattccgttt taaagtttac tgatactgtt
     5041 cctataggtt caatagatac ttcaagttta ggaccgtatt tagctaatat aggacttcct
     5101 aatgctgttc ctataggtat gtaagaactt gctgtcttat ccttttttaa ttcatcttgt
     5161 atttctaaag ctattgcaga tgcaatttca ttcatcatta tagtgtttgc ttgtatcata
     5221 gttattttac cattattatc aagttgtata tccattaaat cttcataatt tatttttcct
     5281 tctaccatct cagcaacagc tttatttatc gacctatttg ctagttcaag agctttagtc
     5341 tctgctaaaa ctgttattgt cggtcttaaa gttttatcta tatatataaa actgcctata
     5401 aatacagaca agaaaagaat tactaaaaaa atagctatga tttttctaaa ttcatttttt
     5461 gtttttctat ctactattct attcaaaatt atcccctcct atttatttat atgtagcttt
     5521 ggcataattt ttataatatt tgtcaaaaat aaataaaata aaaatataga ctttttaata
     5581 tattacgttt atacatatac aatgtacaga atattatagc aaattcattt tttctattaa
     5641 ttacaaaact actcctattt gtgttataat attgcattaa gtaaggaggt taaaatctta
     5701 tgaataacga taatgataaa aatggaaata aaatcaggag aaaaaaagtt agctcatctg
     5761 gtaatacaaa taaaccaatt aatagaactt cagctaacaa gactcgttca acaaaaaaca
     5821 agaaaaaatc taaaaaaagc gataaattta aaaaactaag agtatttggg atagtatttt
     5881 tagttttact agttgttggt acagcaggta ctgctggtct agtatttgcg tcactaagag
     5941 atgtaactcc agttacagaa gctgttttag ataaacagac gaaccaaaca actactatta
     6001 aatacgctaa tggaaaaaca ttatctacag ctccaagtgt aaataaaaag acacccgttc
     6061 cattagataa gatttcccct tatcttcaac atgctgtaat tgcaatagaa gatgagcgtt
     6121 tttatgagca taagggtgtc gatattaaag gtttatttag gtcagtatta aagaccctta
     6181 caggtactaa gcaaggtggt agtactattc ctatgcaggt atccaaaatg ctgttaacaa
     6241 ctgaacagca aactatacct cgtaaaataa aggatattta ctatgcacat gagatgagta
     6301 aaacagtaag taaagataaa atactagaaa cttatttaaa taacttcttc gttggtagag
     6361 gtctagcagg tgctgaggct ggtgcacgtg gttattttga taagtctgca gctgacctta
     6421 ctctagcaga gtcagcactt cttgctggtt caactaaaaa tccatcaaga ttttcagcct
     6481 ataaaacttc taagttagag ggaaatgaaa ctaaggagga tttagagaat aaattattat
     6541 tttttgttaa cacaactgat gatgatttag atgaccctac tcaagtggac tttgatatga
     6601 ttgaaaaaat aaaatcttgg gagcttatat ctaatgatac ttatagacaa ttaaaagcag
     6661 gtacattagt tgttagaaag gctgtaagta atcctgaagc taaaaaaaga caagaaattg
     6721 ttttaaagaa aatgttagaa ttgaaatata taaaacaaag tgaatatgat gaagcaatca
     6781 aagctaaaat agaaataaaa ttgcctcaat catcagataa agtttcttca tctgtagaag
     6841 accttatcga aagtgaagtt ataaatgctt taatggaaca aggacataca aatgatgaag
     6901 ctcaaaactt attctacaat ggtggtctaa ttgtaaacac aactatagac cctaaaatgc
     6961 aagatgcttt agaagaagaa tttgatagaa atagcaattt cccaggacat atggtcggtc
     7021 ctgatggagt tagccaaccg caagctgcaa tggtaatctt agattataaa aatggtgaaa
     7081 taagagcact agctggagga agaaatataa gtggtagaaa aactttaaat cgtgctacta
     7141 accctcatca gccaggttct tctataaaac ctttagcaat atatacgcca gctattgata
     7201 ctctaaaaat aacacaagca actgctctaa gtgattctcg aggaggatat aagtttaaag
     7261 aaaataatga atggaatcca agaactacta ctgctggtca tggttctatg agtttacgta
     7321 aagcacttgc taaatcttca aacacgatag ctgtcaaaac tgctgaaatg cttggagact
     7381 cttatgatga atgtgtagat ataatgatgg attacttaaa gaactttggt ataacaactt
     7441 taaagaataa tcactcaggt tcatctgaag caagtgatag aaaattccca tcattgacac
     7501 taggtggtat ggcgaatggt attactccac ttcaaatggc tgctgcttat ggtacattgg
     7561 caaatcacgg tatttatgta gaaccttcta tttttactac tataactacc tttgatggtc
     7621 aattattagt taaaaatgct cctgaagaac ataaagttgt agaccctgaa gtagcttatg
     7681 ttgttacaga tatgttagaa agcgtaatta ctgaaggtac tggtggtgtt gctacacttc
     7741 caaagggaat gcctgtagca ggtaaaacag gtactacaaa tagtgcatat gatgcttggt
     7801 ttgtcggtta cactccttat tatgttggtg caacttatat tggagatgat gctggtagaa
     7861 aagatgattc tggtaacact ataaaacgta gagaagtccc acatggaagt actagtactg
     7921 caaaactatg ggaaaaaatt atggaaaaaa tacatgctaa tttaacggtt actgaatttg
     7981 aagttcctaa aaatgtatat tttacaaaaa ttaatttaga ggatggagga aagcaatctt
     8041 ctggctctaa agcagcattt attgaaggta ctgctcctac taaagtaagt tctcaaccat
     8101 catctgaaga tacaaaaaaa ccagacaata accaaccaga agaaaataat aataacaata
     8161 ataacacagg tgataatggt ggcggttcta cacctcctga taatggcgga aacaatggtg
     8221 gtggctctac tactcctcct gataatggcg gaaataatgg tggtggctct actactcctc
     8281 ctgataatgg cggaaacaat ggtggtggct ctactactcc tcctgataat ggtggaaata
     8341 atggtggtgg ctctactact cctcctgatg gtggtggaac tccagcaact taataaaaaa
     8401 tagaatttaa ataaaaatat aaggagttgt ctcaaggtga ttaaaaaaat cactttgaaa
     8461 cgctcctttt tttataatta caatatatta tttgtattca taaaaaagag aatcccaata
     8521 accagaatcc tcctttttat ataaacaaat aaatatttta tttttaaagt ttttaactaa
     8581 gtgctttatt cttactttta ttcctaattg tttatatatt cttaaatagt tatatcacaa
     8641 attatataaa cttaatattt ttctaattac tgtataccaa atgtttgaaa tctatttaat
     8701 ttgccatatc tcttaataag catttcccac tcttctttat catagaaatc acacttattt
     8761 ctaccaaata gcttggcaac ttcaattgca aatctcccag ctgaatctaa atcactaaaa
     8821 ttagttgcac ctgtagcaca tccagcaaca ggcatctctg ttgtaattgc tactcctact
     8881 attggtgcat ctgtagctac tgctggttgt aaaatactat ttaagtgata cagattattt
     8941 ccatatggtg ttatatcttg aatagacaaa gggaatacaa atggagattt ccctgttaca
     9001 gtctgcataa tatctaaaag gttatcacta gtttttaata tgtagccttc tttaacagtt
     9061 ggcgatattg caaatcctct agtattgatt actctatttc ctttagtagt atctatagaa
     9121 agtattgcat cacaactact atcaacttca ttttcattca tagtcatcat atcaattgga
     9181 gaatccataa aaggagtagg atagtgttct ttagttggag catctgggca aatatgggtt
     9241 gaaattacaa catcaccatc taatatatcc ccttttcgtt gcatatccaa aagtttagca
     9301 gccactgcaa ttgctaccaa tgctccatca ccatctgaaa caaaacctat aacttctggt
     9361 cttgctccaa tccctcctag tctacctaaa atgccaagag taggagcatc tccacctttt
     9421 aattttccat ttttcccagg aattgtaagc tttactaaat ctgttgagcc tttacttgaa
     9481 gacaattctt ttacagttac atctacttca ccataacctt gtaagtaagt ttttacttct
     9541 tccccattag catttgcttt atctaaaatg tcataaacct ctattacttg ttttaatatc
     9601 atgtctaatc cgatttcctt tcttaatata ttttaaaatt atatattatt tactatacaa
     9661 aatatctact ccacacattg ctaacacctt aattgctttt ataagtgcta ctctgccttc
     9721 ttcaccacca gctgcaacag caaattcatc tgtatgagtt gcagtatttt cttttaattt
     9781 tatatatgct tgtattgcag gtatctcatg agttaaattt cctgtatcag ttgaacctat
     9841 accttgactt aaatctcttt caacatagtc ttcacccaaa acttcaaaat tttgtctaac
     9901 tatattcact aattcagaat cattcttaat ctctttgtat atttcatcta attgaactat
     9961 ttctacatta gttccagtag aaattgcagc tcctttagca caatttttaa gcatttcaca
    10021 aatctcattt aaatattcta tgcttaaagc tcttacatta aatatagctg tagatttttc
    10081 aggaattata ttatgtatgc tacctccatc agttataatt ccatgtactc ttgcataatc
    10141 tttaagatgt aatctcatgc tatttacact gttaaatagt gctattactc cacttaaggc
    10201 acttttccct tcccaaggaa aagcagcagc atgtgatgcc ttaccagtaa aatcaaattt
    10261 taaattaact tgagcaaatg atatatcatc aggcattgaa gcatcacttg gatgtaaaat
    10321 taatgcagca tctacattat taaatacacc ttctttaatc atagttattt ttccacctac
    10381 tctttcttct gcaggtgttc caaaaacctt tacagtccct tctatattat gttttttcat
    10441 gatttctttt aatatgatac ctgcaccaac agaacttgtc cctatgatat tgtgcccaca
    10501 tgcatgtccc attcctggaa gtgcatcata ttcagctaaa aaagcaactg ttttcccatt
    10561 agttccattt gaatacacag cttcaaaaga tgtttctaat cctcctacac ctttagttac
    10621 attaaattca ttttcttcta acaaatcaca taatgctttt tgtgacttat actcctcaaa
    10681 tgctaattct ggatttgaaa ataaatagtc agaaactttt tcaaatgatg tctttttctc
    10741 ttcagataat aactttattt cctctttaat ttttgctttt aattcattca tatttactac
    10801 ctccttaaag cattccattt aatcttaaaa ctgtttgaga tataaaagca gaaccaaagt
    10861 aagtagatgt cataactata aatgatataa ctactaactt ccaactcaaa gtctttaata
    10921 tatctaattg gttacctaca gagattcctg caaaagctaa taatggtgtt actgtagaca
    10981 taaaattgat tttccctaca tttgttgcta tgatatcccc cactggagat attggaagcg
    11041 ataaaacaaa tgcaactaat gtagcccatg caaaacctgg taaattaggt tttttaacaa
    11101 aattctttat tataatagca attatcacca acaaaaatcc agatacactt ccaatcaaca
    11161 aatcttgagc ctgagtctta agtgctatca tttgtccaaa gcaaataata atatatataa
    11221 acaatactat ttttatctgc tccataatag tcttaaaagt tttttccata tatatatcct
    11281 cctttacaat ttattacttg ttcttcttgt ttttcttcct ctaaatcttt caataactgg
    11341 agctactttg ctataatagt agttggctac tggtaaagat aagaataatt ctatatatat
    11401 tccagtaaca gctgtaatca atccactagt agctgaatat gctaaaatct gctctgacat
    11461 ttgtggaacc gtattcatta atgatgctgt tgcagctccc atcattgaac cactacccat
    11521 tcctgatgcc attgctaaag catatggatg aaatcctaaa agtacaccca ctggtgctaa
    11581 aaatgaaaat aataatgttc caaatatact accacttatg taagttccta gtgttcctat
    11641 accttctggt gagtttaatc catacttatc tccaataatt cctagtgctg tgtcacgaca
    11701 taatgaaaaa gtaccaccta atgcacttct tccaagacct aatgctactc caacaggtaa
    11761 tgctatcaac attgtaccca tatgaccaaa ttcttgtaat aaaagtgctg gtcctgcttg
    11821 aagtaatata ccaactttag gccctgcatt aattccaaac attatcccta atggatatag
    11881 tgtcaaagat aataaatatg gagatacatt tatttcatta tcccctataa acttttttaa
    11941 ggctggtata actctcccta ataaatgagg agaaacagcc attcctatga atatagccca
    12001 tagtatacta agtaaagtta cattaattcc cataacttta aatgaaatag gtccaattaa
    12061 ttctgccaat attgtgatta taaaggctgc tattatggca tttctaatcc ctgctttttc
    12121 tttcatttct atacctcctt gtaattttta taattttctt ataatataat tgttagtgat
    12181 tttattatat aacctatcat tgataatgta taatatatat ttattcatca tttttatata
    12241 cttttagtta tgaatcaaaa aaatattata gattcatgat ataaaataca aataatttat
    12301 taatttatat tgttaaaata acggattttc aaataattga ataaaattat tcattcatat
    12361 tataaaaact atctcaataa ataaaggagt acaatgtact tatatacacc tactcctttt
    12421 aatttttatt tatattattt gttaaaaaac ttcacataat ctataatatt tttaataaac
    12481 gtttgatact taaaagctta ctactttatt cttttaacgc tatttcgtat tattaacctt
    12541 ggatataatt ttctcggaat gtgttctgta ctctttttat ttattatatt tactaaacta
    12601 tctactccat tttttataac ttgctctctt gggtcatcta ttgttgataa atgcgaccta
    12661 aaatatgata ttaattcaat attattatac cctattatgg aaatatcttc tggtacattt
    12721 ataccataag tagtttttaa ctcttgtatt atagaaatcg ctggtacatc ttgttgtaca
    12781 aatatagctg aagctttttt tattttatca atgtattttt ctaaaaattc aacttgagat
    12841 tcaaaatcca ttttagattt aatgacttct gtctttaaat ttgcttcttc catagcattc
    12901 aaatatccct tggttctatc ttcatgcatt tttgaactct tatcatctga agttactgtt
    12961 attatatctt tatgaccatg gtcaattaaa tgcttggtag ctatataacc tccatacacg
    13021 ttatcgtccc aaaagaaatt atctacttct cctataaaag atggtttaaa atatataaat
    13081 acatgtggaa aattattgtc ttttaaaaaa tcatactctt ctttttttat tgattgagac
    13141 acaattacta atccgtcaac catttgtcca tttaccattt tatatacatt actatcacca
    13201 ctaatgttat tattaggctg tattataaaa tcgtatttat tagtctcaat agaatttata
    13261 gaactatcca ttatatcact aaaaaacttt ctagtatctt gatgattaaa attatttgaa
    13321 aagattaccc ctatcctgtt agtttctttt tttgctaaat ttcttgcatt tacattaaaa
    13381 tggaacccta gtctatttgc ctcttctacc actttctttt ttgttttttc agatacatta
    13441 ggattattgt ttaagcacct agaaacagtt gaataactga tacctagatt ccttgcaata
    13501 tctttaatag ttaccatctt tatcccctac ttcacttcat tttattttga taatataata
    13561 ctacactatg ttgtaaataa ttgtcaactt caattatgta aacgcttctt tatataaaaa
    13621 acaggtggaa tctaaaagat atccacctgc tttataaaaa tttattattt caaaaactta
    13681 ttattctttt aataaagatt tatggttttg cttttggagt aaatactact gacataatat
    13741 atccaaagaa tatagctgct gctattccac cagctgtagc agttgtacct cctaaaaaaa
    13801 tacctaaaaa accatcactt tgaattgatt ttattactcc tgtagcaagt gaatatccaa
    13861 atcctattat aggaactgtt gcacctgctg ctgcaaactt aactaatggc tcataaagtc
    13921 ctagaaaagt taaaactaca ccagttgtta catacgttac cataacatat ggagtttgca
    13981 ttttgaaata atccatcatt acttgggcta ttaaacatat aattccacct acaataaata
    14041 ctcttacata gtccattaac atattatatc acttcctact catttactat tactactgca
    14101 tgtgcaacac atggtattgt ctgcttttgt agtgtacttg tcggtgaaag tagtgctcct
    14161 gttgatacaa gcattacttt gttaaattct ttttttctca acttatcata tatatatcct
    14221 gcaaacactg tggctgaaca cccacatcca cttccaccac agtggacatc ttgttcttta
    14281 aggttaaaca tctctatacc acagtcagta taaacttttg atatatctac acctttttct
    14341 tttagaaagt cttctgctat ctgttttcca agagtaccta aatctccagt agcaattata
    14401 tcaaagctat ttgggtcatc attagtatct tcaaagtaag agtagatagt atctattgct
    14461 gctggagcca tagctggtcc catattatta ccatcatcaa taccctcatc tattacttta
    14521 ccaacagtaa catactttac ttttggaccg tctccattag gagctaataa tacacttcct
    14581 gctcctgtaa ctgtccactg ggctgtcatt ggtttttgat ttccaagttc aagtgggaat
    14641 ctaaattgtc tttctgctgt acaatagtga cttgatgtac ctgacagtac taaatcagca
    14701 aaaccaccat ctataagcat agaacctata caaagacctt ctgccattgt agaacaagct
    14761 ccatatatac ctaaaaatgg aatagccagt tctcttgctg caaatgatgc tggaactatt
    14821 tgatttatta aatcgccacc tagcatataa tttacatctg acaatttttt acctgccttt
    14881 tggatagctt gttgagatgc agtctctacc attttacttt cagctaattc ccaagtcttt
    14941 tcaccatata aatcgtcagt cataatcata tcaaaatagt cctttagtgg tccttcacct
    15001 tccttaggac ctactatagt tccagttgat attatggttg gtttattttc taacttgact
    15061 gttctttttc caattctttt atttttcata ttttcacacc tttttaattt tgcattttac
    15121 tattcaaatt tttaatatta attaaaaatt ttaattaaat ctgcacaatt atttttcaat
    15181 tagttacttt agtagctatt ttcagatttt ataccttctt cataattaat aaaatttaaa
    15241 ttaaataaaa atcatctaaa acatcttaaa aatataataa ataattccac ataaaataga
    15301 agaacctata ccataaacta aaactggtcc tgcaatttta aataagtttg cacctacacc
    15361 taatacatag ccttctcttt tatactccat tgctggagat actattgagt tagcaaaacc
    15421 tgttattgga attatagaac cagctccagc tctttttcct attaggtcgt aaactcctaa
    15481 tccagttaaa aatgccccta taaatattaa tgttattgat gttgcagaac tagcacctag
    15541 tttatcaaga cctccaactt tcatatacaa atcatttatt gcttgcccta tcatacaaat
    15601 aattccacct acaataaatg caagtgtata gttttttaaa tatgtaggtt ttgggcttat
    15661 ttggtctaca tattttttat aatttttatc catactaaac acctctctaa agtattattt
    15721 gttaatttta aaaaaataaa cctattattt attttgacta tctaaagttt ggtcaaaaaa
    15781 taaaaaagat gcctaataaa gaaaaaatct atttttccat aaagacacct tgtttttata
    15841 tttttacttt tttaatgctt tttattattt taatatcttt taataattta aaaacttaac
    15901 ataaaaagtt attacatttt attttagtaa tatatttatt atattttgtt attctacata
    15961 tcataagtat tatcacgata tatattcttt taacttagac aatactttct tctctatcct
    16021 agatacttga acttgtgata tattgagcat ctctcctatt tcactttgag tcatgtcttc
    16081 aaagtatctg agaactatta tttgacgctc tctcttatcc agtcttccaa gtatgtcttt
    16141 taacaatatg ttatccacta ctttttcttc ttcactttct cctttcatgc ttattttatc
    16201 aataaggcat attggagaac cttcctcttc atgaataact ccttgcaaat actcaacatt
    16261 gaaattagct tccatagcca ttactaaatc ttctttttct acatctattg ctttagctaa
    16321 ttcttctata ctcggctctc tacctaattt tttagttaaa gcttcacttt ccatctttgc
    16381 ctttacagct atttgcttta acgaccttga tacttttatc ataccatcat ctcttaagta
    16441 tctctttatt tcacctaaaa tcattggtac tgcataagta gagaatttta cattaaattt
    16501 tgggtcaaat ttatatattg attttattaa gcctatagaa cctaactgaa ataaatcttc
    16561 tctatcatat cctatattta aaaatctaga tacaacgctc ctaactagac ctaaattgct
    16621 tgatattaat atttcttttg cctcttcatc tccattttga actttttcaa taagttctag
    16681 agtctcttca tgactaagaa gaggtttttt ttcttctctg gcaacagtta cttccataat
    16741 aaaacctcac ttttggactt tatttaggca catttatttt tttagtcatt tcaattctag
    16801 tcccattatc ttttacagaa cttacctcta catcgtccat aaagcttttc attactgtga
    16861 atcccattcc tgatctatca agttctggtt ttgatgtata aagtggttcc attgccttct
    16921 ccacattttc tattccatac ccttcatctt caactataat ctttatagta tttccttcta
    16981 tctcacatct taagaaaaca aacttagaac tgtcttcttc atatccatgt attatagcat
    17041 tcgtaacagc ctcagagaca gcagttttta tatctactaa ctcatctact gttgggtcta
    17101 acttagctgc aaaggatgct actataactc ttgctaaact ttcattttca gatattgccg
    17161 aaaatttaac ttccataata ttattcatca catactcctc cctacaaaga acttagagct
    17221 tcttcatacg tatcataaat gccaataatt ttatttaacc cagataaatc aaaaatcttc
    17281 ttaactcgtg aacttatatt aattactgaa actcgtcccc cttcattaga aatcttttta
    17341 tatctaccta tgatgacgcc tatacctgaa gaatccataa aattaatatt ttcaaaatta
    17401 aatacaacat tttttacttg atttacactt aataagttat ctatttcttc ccttatttca
    17461 ttggctacat ggtggtctag ttctgagcac ataaattcta tgtatagatt cttatgttct
    17521 aaggaataat ttaccatcaa aaatccctcc ttcaatagtt ttgtaaaaat agtaactttt
    17581 aatcaattct ataattatat ttttattcct tcaatgaaat ttaactagtt ttgtcgtatt
    17641 atttctacca tactttcatt atatgttacc tgacccccaa aatctgatat accagtgtct
    17701 gttaaactat taggatttcc atgtttcttc caccaaccaa catacatttt tactatataa
    17761 ttacctactc catcatctat atttatttgt acatttattt ttgctttttt tgacctcaat
    17821 atcacaatat ctttctcctc aatacctact tttttagcca ttctctgatt tatatatgct
    17881 tgagctatag attttttgtc cataaaatgc tgactaaata aagtatctgc atgatgatta
    17941 gttaataatc taaaagaaat atttttatct tctatttctt tatatttatt gcttatatat
    18001 acaggtgttg gacttattcc caagtttttt atactttctg aataaagctc gtattttcca
    18061 gatggagtct caaacttctt atcttcccaa gcaacagggt tatgtatagt aaagtaattg
    18121 tttttaagtt tttctatatc cagatttttg tcaaaacgct taagtggttc aatcactttt
    18181 tctaaataag ttctcttttc tacaaaagga taatcattta atcccatctt tttagctagc
    18241 tccataaaga agtaatattc atccatcaat ttatgtgctg gctttacagc tctttcatta
    18301 taggttatat atggattggt cattgagcta taaattatat cttcactctc cagtgtattt
    18361 gtacacggta taaacatgtc acataaagta actgtatcag ttataaacat atcaaaacat
    18421 actttaaatt caatttttga aaacaccctc tccaattcta ctaaatctgg cagttgattc
    18481 agcatattac ttttagttat cacagccatc tttataggaa tattatcttt gattgactta
    18541 ttagataaat tatacaattc atttgatata taatctgttt tatttgatgt tatatcaagt
    18601 tcatctaata cataatttac tttatttgat gtcatatcaa gttcatctga tacataattt
    18661 actttatttg atgtcatatc aagttcatct gatacacaat ttactttatg taatgccata
    18721 tcaagttcat ctgatacacc atttacttta tgtaatgcca tatcaagttc atctgataca
    18781 taatttactt tatttgatgt tgtatcaagt tcatctgaca cataatttac tttatgtaat
    18841 gccatatcaa gttcatctga tacataattt actttatttg atgttgtatc aagttcatct
    18901 gatatgtaat ttactttatg taatgccata tcaagttcat ctgatgcata atttacttta
    18961 tttgatgtat tttttaaaga ttcttctata aatttactga tattacttac ataaaactcc
    19021 ctatcttcac catatgattg gctattgtaa gggtcagaat ttataacact cggataaact
    19081 ttattagcat agtttacccc tccaccacta aatcctattt gaccagttat agcacctaaa
    19141 gcatctattg ctcttattgt gtttccacca tttttatatt tttgaagccc atatccaaca
    19201 tttatacttg aatatttgtt agtatataaa tccactaact ctcttatatc attctcttta
    19261 acaccacatt catcaattaa aaaacttaat tccaatgaag ataaatattt tttatattct
    19321 tcaaaaccaa taacatacga gtttatatat tcttcatcat ataatttatc ttccactata
    19381 atttttgcca tagctatagc taaagctcca tctgttccag gatttacttg tacatactta
    19441 tctgctattt gagctgtttt tgtatatatg gggtcaatca ctactatctt tatccctttt
    19501 tctttagctt ttttaattat ttgcatagta tgaattgtag tatatgctgg attttttccc
    19561 caaacaaata tacttttact atttaacata tcttctatag catgactctt agctactcca
    19621 aaatcatatt tttgagcatg catccctgca ctccaacagg gaccaccctt atgtctgcta
    19681 acacctccat aaaaattaaa aaatatatct cctatgtatt ttagcacaga cccacttcca
    19741 tattggtcat aatgcatgac agactttgat gtatactttt ctttatagta tgtaagcttt
    19801 tctgccatta tttctatagc tttatcaaaa gaaatctctt tccatactcc atcaacttta
    19861 agcataggag tctttattct atctttatga tttaatctat ctaaatgggc catccctttt
    19921 ttgcatataa aaccttttgt ataaggatga tttttatctc cttcaatttt tactacatta
    19981 tttcctttag tataaacatt gaatttacaa cagtcatgac aatctaatgt acacccatga
    20041 cttaattttt ttattatatc cataaaatat ccttctttct actttcttac cttattaaaa
    20101 attaacatat atactataat ttattaaact ttctatgttc aaaactacag tatataaaac
    20161 atagctatat tttatcaaat taagtttaaa aatacttcat aaatataata ttattaaaaa
    20221 attctctttt aaaaaactaa caatcttata tgtttactta aacactatgt tttttaatta
    20281 caaaaatgag gctatctcaa aataaagata aacctctttt tcattgttta aatgctgaaa
    20341 atatatttaa ttttatacaa aaaagtgcct catgaactaa agagttcatc ttgagacact
    20401 ccataaaaac cttacataac ttgtccacca gtaatattta tagattgacc agtgcagtat
    20461 tcagcttcct ttgaagcata aaatgtaagc atatttgcaa catctataaa tctacaccct
    20521 ctttttaaag gtactttatc tatataaact tgcttgactt ctgattcagg tattcccaat
    20581 tttactgcat attgaggaat taaactttca aacatatcag aatcaagtaa attaccgagc
    20641 atcagtgcat ttacagttat cttatgttct gccaaatcta gcgctaaact ttgagtaagt
    20701 cctactccag caaatttacc tgctgaatat cctgaattat gcttgcttcc cactctacct
    20761 gattttgaat ttatctgtat tattctaccc tcaatacctt ttgctatcat gactttagat
    20821 acttctcttg caaatagaaa gtacccattt aaatttacgt ctacaataaa tttaaaatct
    20881 ttgtatccaa aatcagttat ttttttactt acagccactc ctgcattgta cactaataaa
    20941 tctattctat caaaatcatt ttcaatagct ttgacagtac ttataacctg tctttcatct
    21001 atggcattac aactatatcc tacagattta caaccaaatt cagtttttat ttcttcagct
    21061 actttttttg cgttgtcttc atttaaatct gcaatagcaa catcataacc tactttagct
    21121 aaatgtttag ataaatattc acctaaactt cttcctcctc caacgactaa agccactttt
    21181 ctcattttca tttccccttt tttatcacat taaaagttaa cttgattagt taaattgact
    21241 tttatctata atttacttat aatatgatta gattcgtttt aaattttatt ttctaattat
    21301 ttttagtata gtacctacgc caataggtgc tatttctttt tcttcaagat ataaggttcc
    21361 tccaattgct ccatcttttt cacctgtaaa cttaaatgtt atatgaccta attctgaaag
    21421 attttggttt actaactcac caacagaagt aattttgtaa tcaacattat ttattgatag
    21481 cacatcatcc gtaagtattt cttttactaa attattttca gaatgtatat aacagtaatt
    21541 ttctaactct tgaggagcat tatctttgaa agttacaaac atattatgtt gtaaaaattc
    21601 atttgcatta tctcctattt tatttatttg agtactgtat attaattcca tatcaactga
    21661 acctctctct aattatttat aaagtattct tctatttata taacccaaag cttgctaacc
    21721 atgctaatag aacagttggt gcacctgtta aaaatctaga atataaaact gacggaactc
    21781 ctacttgaac tgtatcaggt tcagcttctg caagaccaag acctactggt ataaagtcac
    21841 aagctgcttg tgagtttatt gcaaacaatg ctggtaatgc taaacttggt ggaatatttc
    21901 cttttcctat ttctgtacca accaataccc ccactatctg agctataaca gctcctggtc
    21961 caagaaacgg agacaacaac ggaaatgaac atattattga taagacaact aaacctccaa
    22021 catttccgat taatggagta agtaaattgg ctacccaatt tcctataccc gattgattta
    22081 ttatacctat taggactgca acgaaagcca taaaaggcag tatagtatgt attaatgtat
    22141 ctatagtatc cctaccagct tgaaaaagag tacttgtcac atttcctagt gctataccta
    22201 tttttgcaac aattccttga ctctgctcac ttatcttctt tttagtatca taagccatat
    22261 ttcttccctc ctactacctc aattataact gctctacatt tgttggtttt acccctgaaa
    22321 catatatatc ttcttttata aacattgcta atggtccact ttttcctgtt ttcattatat
    22381 ttatagtcgg tattttcttt tgaggatata taccacatct caatgttcca ccacaattta
    22441 ttattacaca tgcgatttca tcatctttaa caccctgtga aaatccatct attaactcac
    22501 atcctgtaag ttcagctatt tttactgcag tttctggctt tgctccccca gtcacatata
    22561 ctaccttatt cttcttttct gttggttcta ttatcaatgg tccaccccat cctccagaac
    22621 cttttactat tttaactttg ttaaatgcca tataatttat cctcctctat acactatctt
    22681 tttatttgaa aaatttattt ataccttaaa gtaattatcc aatctttata tctgaattta
    22741 atgctattcc ttgttgtttc tctacaaatt ttgttgtata gtcagtaact acacctttaa
    22801 taaagtttgc aactataccc actaacaaat atctaactgc taaatctgct gttgagaatc
    22861 ccaaagttgt tataccattt gcaattccta gatatataaa tagttcacct ggattgatat
    22921 gtgggaataa tccattcatt gtatggcatg aaaagcttgc tgctgcaaag taactaggtt
    22981 taaacttttc tggcaagaat cttcctaatg atagtgtcat tgggtttgca aatacaaatg
    23041 taccaaggac tggtaatatc aaatatctag taaatatatt tgcagaacat ttttttgcaa
    23101 gtctctcgac tctatctgta ccaataaagt tgataattgc attcattgta actaataatg
    23161 ctactaaaag tggtactata tctgttacaa aacctacaaa ttgttgccca cctgccctaa
    23221 ataaattcat aaaactatct gcaccacttg ctaatacttg aaaaaattgc gtcatattaa
    23281 ctcctcctta taaatatatt tttttaaact acttccatcc tacactcttc atcagtactc
    23341 agattatttg tatcttcaca tttatttttc tcaaatgtta tgtactgttt gactgcatct
    23401 agtattgctt ttttaagtag tttattgtaa acagttaaat ctgatttttc tatatactct
    23461 aagctctttc ctaccaaacc ttcaaatgac tttactcttg ccaatactgt aacaccttgc
    23521 atttttctag tctcgacaat cacaccatca tcatttataa gtatcaacac aattgtacct
    23581 gatgaaattc ttcctttttt tctgccaatt gccactcttc cttttctttt tagttcaata
    23641 taatttttat taaaatcttt aagctgtaag tatccaagaa aaatatttaa taaatacact
    23701 gtaataagtg atgctataat aaaaattact gggtccatat tattacctcc tcttggtaat
    23761 tattttataa aattcatcaa atgattttac cttagcaagt tcttctacca tctttttatc
    23821 tctccctact tcaagtactt cttcataact ttttattatc aggtctgtgc tatctacatt
    23881 cttatctgga attatcatca atattattat tctaatttcc tttgtatccc aaatcactgg
    23941 tttttctaat attccaaatg ccagataaag attttcccca ttagtattaa ctgagtgagg
    24001 caatgctata taattatcta atgctgttga agatttcttt tctcttttta ataccttttt
    24061 tttgaactct atatcaataa ttcctttatg aactaatttt tctaacatat cttctaaatt
    24121 ttccataaac gtactcttat tcaatataaa gaacttatcc tcttcaatta atttacctat
    24181 aaaagggata tttttttcaa tcttttttat agacttaaga tttatactat ttttcaaaag
    24241 tattgcattt tctatctctt tctttatact ttcttcatta aataacgcat ttactctaaa
    24301 aattggaaca tctaagtctg ttttgaaatc tactgttgta aatactaaat cataatactt
    24361 taataaatct aaattagctt tagcttctat atcagaaaaa gtatttactt ctacactttc
    24421 tccaagtatt tttcctatct ttattctaat aagttgtgca gtcccaagac ctgttccaca
    24481 aacaacagct accctattta catttagaac ttttcttgaa tttttttcaa aataacttcc
    24541 aaaatgtaat gctatatatc ctatttcgtg gtcacatatt ttcaagtcaa acttttcctc
    24601 aattatcatt gcagctatct ttgcaacact atatggaaat gtatatcttt cctttatttc
    24661 ttgtaaaaga ggatttttta cccttatgtt gaatctcatt ctattaagtg caaaatacaa
    24721 gtgatattcc aaattttcta taagcttttt atcttcttta aaatcaatcc ctgaggtctc
    24781 taataaaaaa ctagttactt catctacaac ttcctttacg ctatcattta tctttatact
    24841 gctaagtgct aattttgtac taggagcttt tctacctatt aatggcattg tcaaaaatat
    24901 ggtttctttt tcatttaaaa ctatattaaa tatcttttcc aataaagctt tgagctttaa
    24961 tcctaaagta tattcatctg aacatcttat cacttcaaat ctcttatcta tcttttcaaa
    25021 tttgtaccca tttagatttc ttaagacaga catgattata tatctttcaa catctctcaa
    25081 gacctgttct gttatgtaga gttcttcttt tttaaataac ttttttaatt catctctaag
    25141 acattcaata tcataatctt taactaaatt tatctgatta acgttttcca agacatcaat
    25201 ataattttca tacaatctat caaggattaa taatcttata tccatttctt caccaactaa
    25261 aatcatacct atatttggct tcctttttaa ttctaaatca tattcagcta aaattctgtc
    25321 tgcttttttt aaatccttta ttaatgttgt tcttcctata catatctctt cagccaaatc
    25381 atctatggta attggattgt tggtcatagt taaaatatca agaacataat ttattctttc
    25441 atcaggtgaa tttaaattta taaaatttga tagctttcct ctattaaaat ttacaatctc
    25501 aattaattta ctttcatcct caattcttat actatatgta cctttttcat ttttaactat
    25561 tttagcaata ccacctttta attctcgatt aatctggttt atatagtttc tgatagtcct
    25621 agtactaaca cccaaaacat ttgaaaattg ttctagagta tttgtgtctt cttctaacac
    25681 catttctaaa atcaaaaaaa ccctagggtc catataagtc attgacatct ttttctcccc
    25741 tttgttatct tacatttttt attataatct aaactatata gataattaat attctctttt
    25801 tcaaatcaga tttgaaaaaa aggaactaat atacattttt cacaacaatc tggaaaatta
    25861 taacatcata taaaacaaga aaagccttat gctgttaact cttacagatt atctactatc
    25921 tgttttgaaa acacatcagg ctttttaaat atccaatata ttattttata tattttctaa
    25981 ttatagtttt gtatactata cgttattttt tcttcttgtt tgctttttct atattaatct
    26041 tattaccttt tatcttaata tctttcatct tttcaattac tgtttttgca tcttttttag
    26101 gtatttcaac aaaagtatac ttatcatata tatctatagt acctactact ttacctggta
    26161 ttccaacttc tccagctatg gcaccaacta tatcttttgc ttgtactctt tgatttctac
    26221 caatattgat aaataatcta atcataccat ctttagctcc agtaccacct tttctatctc
    26281 cacgctctct tctaggtttt tcttctatta tttcttcttt catttcttca cctagagata
    26341 gttttacaag tgcagcagct atatcaacca ttgcataatc ttcatcatta cagaaacctt
    26401 ctaaccattg taattgttta gttaagtgac cttcttctat agtttgttta acttgtgcaa
    26461 agaaagtacc tacttttttc tcttcaacat cagttattgt tggtatatta tgctttatta
    26521 gtttagattt agtatatctt tctatatctt tcatctttct catttctttt ccaaatacaa
    26581 aagtaaatga cataccttct ctaccagcac gaccagttct accaattcta tgaacgtaat
    26641 actcttcatc ttgtggtaag tcatagttga atacacattc aacatcatca acatctatac
    26701 ctctagctgc aacatcagta gcaacaagta tatctattgt accatttcta aacttatcca
    26761 ttactatatc tctttgagtc tgttttaagt caccatgtaa tgcatctgca aaatatcctc
    26821 ttgcttgtaa atctcctacc aattcgtctg cttttctctt agtattacag aaaacaacag
    26881 atagtttagg gtcatataca tctactaatc tacataatac ttctaattta tttgatgacc
    26941 tagtttctat atagtattgc tttgtatttg aaactgtaag ttcttttcta acaactttta
    27001 tatgctctgg gtctttttga tatctcttag ttaattccaa aattcctctt ggcatagtag
    27061 ctgaaaagaa agttgtttgt ctttcttctg gaatcttact taaaatcatt tctatatctt
    27121 ctctaaatcc catatctagc atttcatctg cttcatctaa tataatcatt tttacattat
    27181 ccatctttaa tgttttacga ttgatatggt ctattgtacg tcctggtgta cctattacaa
    27241 cttgcacacc actctttaga gattttattt gtctatctat tggctgacca ccatatatag
    27301 gtaatgtctt tattccgtgc gaatacttag ctaactttct tatttctgtt gatacttgta
    27361 ttgccagttc tcttgttgga caaagcacta cagcttgtaa acttctatta tttgggtcta
    27421 ttgtttctag tatagggata ctaaaagcag ctgtttttcc cgtaccagtt tgagcttgtc
    27481 ctataacgtc tttacctgac aaaatcgcag gtatagactg tgcttgtata ggagatggtt
    27541 cttcaaaccc catttcagct atagcttttt ttattccctc acttattggt aaatcttcaa
    27601 actttgttat attcatatat tattcctctc cgttatcaat taatcttaac ctatccatta
    27661 tatacttttt taggatattc tgcaattaat attttaaaca gtatagttaa ataatataca
    27721 tgaaatacaa aattgatatg tacagaaaat atgtgaataa catcaatata ccttgtattc
    27781 tactaagtct attagattta agtgttggta ttattactat taataataat aatatcatga
    27841 atggtatatc caattgtcta ttttgagata gtattggtat gttatttggt attgctgata
    27901 cagctattac tgatactata ttcaatatgt ttgcacccaa aatatttcct actgatattt
    27961 catgatgatt ttttcttata gcagtaatcg acgaaactat ctctggcaga gaagttccaa
    28021 gtgctattat agttaaactt actatacctt gaggtatatt taaaaaacta gctattatta
    28081 ctccactctc tataaggatt tgtgaaccta ttatcatcat tatcaatcct gtagcaaaaa
    28141 gtaatagtat ttttacaatt tctaatacgg aaaaacctct ataatttttc ccttttttag
    28201 tagatatgtc tttaatagtg ttatttttaa tatttctatt tttagtatca gattttccaa
    28261 cgacacttct ataattatta accatataaa agattaatat tattataagt aataatgaat
    28321 cacctcttgt tataactcca tctaaactca ataaaattaa aactataacg gatactatta
    28381 atagtaaaga cttagaaaaa aacatttttt tatctacatt aaatggactt ataaaaacaa
    28441 ccaaccctaa tgctaatcct gtattacata ttatagaacc aactgcattt cctaaactca
    28501 tagtagtatg accatcaata gaagcaagta gagacactgt aaattcaggt aatgttgttg
    28561 caaaactaac tatagtagct ccaagtataa tttctgatat attcgttttt ttacctatct
    28621 ctacagtgca atttataaag atatctgcgc ctttagtaat taataggaaa cctactaaaa
    28681 ataataccac tgtgataaac aatctatcac ctccccctat taaataaata ttcaatttgt
    28741 gaagatgtat gctttttctt ttttccataa taaaatttat ttatcctaaa caaaaaataa
    28801 aaaatatttt ctccttaatt agctatttat ttgttttatt ttatttatat atgggtataa
    28861 tttcaccaca ttattaacat ataatctgtt ttatacttta aagcgacaat tttttatttt
    28921 ttatgtatac aggatacgaa taatatgata ttattatatt agaaaatata tttttaaaaa
    28981 aatatataaa ataaattaag tatataaaaa ttaattttaa tagtattatt tatcatttaa
    29041 atctaaggag gaaatactta atgaatgcat ggcaaggatt taaaacagga agatggacta
    29101 aagaaataaa tgttagagag tttatacaat taaactattc tccatatgag ggaaatgact
    29161 ctttcttagc tggtgctact gaaaatacta aaaaattatg ggacgaagca atggtcctat
    29221 ttaaaaaaga aagagaaaat ggtggtactt tagatgttga tacaaaaact gtttctggaa
    29281 tagctgcata tgctccagga tatttagata aagaattaga aacaatagtt gggttacaaa
    29341 cggatgcccc tttaaaaaga gctgtcatgc catatggtgg tataaagatg gttgaaaatt
    29401 catgcgaagc ttttggatat gaattagacc cagaaataaa agatatattt actaaataca
    29461 gaaaaacaca caaccaagga gtttttgatg tttatactcc agaaatgaga gctgctagaa
    29521 aatctggtat aataacaggt cttccagatg cttatggtag aggtagaata attggtgact
    29581 acagaagagt tgctctatat ggtgttgatg ctttaataga agataaaaat gagcaaaaga
    29641 aatcattaga agtttcttgc atggatgagg aagttatcag attaagagaa gaaataactg
    29701 agcaaatatc agctttaaat gaacttaaaa aaatggctga atcttatgga tttgatatat
    29761 caaaaccagc aactaactca aaagaagctg tacaatggtt atactttggt tatttaggtg
    29821 ctgttaaaga ccaaaatggt gctgcaatgt ctttaggtag aacatctact ttcttagata
    29881 tatactttga aagagattta aaagctggaa tcgtaacaga agaagaatta caagagtata
    29941 tggaccattt tgttatgaaa ttaagaatgg ttaagttcct aagaactcct gattacaata
    30001 acttattctc tggagaccca acttgggtaa ctgagtgtat aggaggtatg ggaatagatg
    30061 gtagaacatt agttactaaa aactcattta gaatgttaaa tactctatat acattagggc
    30121 cttctccaga accaaactta acagttctat ggtcaactaa attacctcaa ggattcaaag
    30181 atttctgttc taaagtatct atagatacaa gttcagtaca gtatgaaaat gatgatttaa
    30241 tgagagcata ctggggagat gactatggta tagcttgttg tgtatctgca atgagaattg
    30301 gtaaacaaat gcagttcttt ggagctagag ttaacttagc taaaacttta ttatacgcta
    30361 taaatggtgg tgtagatgag aaatctggtg ttcaagttgg accaagattt gaacctataa
    30421 cttctgagta cttagattat gatgaagtta tgagtaaatt tgaaccattc actgattggt
    30481 tagcaacatt atatgtaaat actttaaatg taatacatta tatgcatgat aaatattctt
    30541 atgaagcatt agaaatggca ttacatgata gagatatatt tagaactatg gcttgtggta
    30601 tggctggatt atcagtttgt gcagactcat tatctgctat aaaacatgct aaggttaaaa
    30661 ctattagaaa tgaacaagga atagctgttg attttgaaat agaaggagat tatccaaaat
    30721 acggaaataa tgatgataga gttgatagta tagctgtaga gttagttgaa agctttatga
    30781 ataaaataag aaagaataaa acttatagaa attcttatcc tactcaatct atacttacaa
    30841 taacttcaaa tgttgtttat ggtaagaaaa ctggtaatac accagatggt agaagagctg
    30901 gtgctccatt tgctcctggt gctaacccaa tgcatggtag agatactaat ggtgctttag
    30961 cttcattatc ttcagttgct aaattaccat atgaacatgc tcaagatggt atatctaata
    31021 ctttctctat agtacctgct gctttaggaa aagatatgac tgaaagaata aacaatcttt
    31081 ctgcaatgat ggatggatac ttcgctcaaa atgctcatca cttaaatgta aatgtatttg
    31141 atagagctac tttagaagat gctatggaac atccagaaga atatccacaa ttaactataa
    31201 gagtatctgg atatgcagtt aacttcataa aattaactaa agagcaacaa ttagatgtta
    31261 taaacagaac attccacggt aaaatggctt agtctttaaa tttttatact ttaactaaga
    31321 ttactactgt gtaaaaaata aaaataaaag gctatcttat atttgaatta tttctggtat
    31381 aagatggcct tttttagaga aatattataa ctattgataa ggttattaaa atatattgtg
    31441 aggtgaactc tatgattaag ggaaagatac attctataga aacgtttggt actgtagatg
    31501 gaccaggaat aagatatata ttattttttc aggggtgtcc tcttagatgc aaatactgtc
    31561 ataacaggga tacatgggat attaaatcag gaaaagaata cacagttgat gaaataataa
    31621 cggatgctct taagtatact tcttttatga agttttctgg tggaggtata actgcctctg
    31681 gtggtgaatc cactcttcaa ccagaatttt taagtgaatt atttaaaaaa gcaaaagaaa
    31741 atgatataca cacttgcttg gatacatctg gatttgtaga tatagaaact atagacccag
    31801 ttttagataa tactgatttg gttttacttg atttaaaaca tatggttgag gaaaaatcta
    31861 ttgatttgac tggtgttggt atggataagg cattaaaact tgctagacac ttagaatcaa
    31921 gaaatattcc tgtatggata agacatgttt tagttcctgg cattactgat gatatagata
    31981 atttagaaaa actaggtcaa tttgtagcta cattgaaaaa tgtagaaaga tttgaattgc
    32041 taccatacca ttctatggga atacacaaat gggaaagttt aggtatcgat tatgaactaa
    32101 aagatgttcc tgatgccact aaggaagatg tccaaaaagc tagtgaaata atctctaaat
    32161 ttggagtgaa agtatataat agttagtgta gtatattaat cctttataga agacataaca
    32221 aaatagggta aagtgtaaat ttttaataaa cttcaaaact tccactttgc cctattttta
    32281 tatactatat atctcatttt atatacatca ctttgatagc tgaaatttat aaaattcaga
    32341 ggcacttaca ggtcttccaa ataaaaaacc ctgaataata tctaccccta agctttttac
    32401 tatatcatac tcttcataag actctattcc ctcaacacaa acttttaaat ttataatatg
    32461 agctaattta ataatatatt caagaaaagt atattcataa ctattatatg taatattctt
    32521 aacaaaactt ctttcaattt ttattatatt aacagacagt tctttaaggt aatttaaaga
    32581 tgaatatcct gtaccaaagt catctattgc aatatatact cctataccct ttaaactaat
    32641 aaatttatca tttagtaaat ttatatctgg tatccaacaa ttctctgtta attccaaaat
    32701 taaaaattca ggtcttaatt gatactctac taaacattct actataaaat ctctaaaaaa
    32761 atcttccttt aactgaatat acgatacatt tacagatatt ttaaagtctg gatttatttt
    32821 atgccattct ttacactgtt ttacagcttc ttttataatc cacttcccaa ctggtataat
    32881 taaattactc tgttctagta ttggtataaa ttcaacagga gatacttctc cataagtact
    32941 cgaatgccat cttaaaagta cctctgcccc tattacctct tttgtaacag catttacctg
    33001 gggttgaaaa aacagctcaa agtcattaaa attattttca acgcactctc ttagtttttg
    33061 ttgcattgaa attaccttta gtttattttc atagagctct tgtgaaaaaa acttaattct
    33121 atttttacca ctaatttttg ctatatccaa tgcaatatca gcatgtttaa ataaatctaa
    33181 ataattatct ccatcttctg gatacatagc aacgcctgca gtcactgtgc aatagtactt
    33241 acttgattca atttcatgct gagtatttgt atacatctgt atcttttcat atattttctc
    33301 tatagtttct ttagtacaca tagggtaaaa aaatgcaaat tcatctccat ctaacctata
    33361 caatcttaca tcttttggaa gatattccag tacttcagta gcaattgcac gcaacacttt
    33421 gtcaccataa gaatgtccat atttttcatt tatattttta aaattatcaa tatccataat
    33481 aaacatagca ccatttttat aaattttctc ttttataaga taattcattt tatgttcaaa
    33541 ttgttctcta ttccacgttc ctgtgataga atcaaattta tttttttcac caatattctt
    33601 tattctcccg actagaaata tagtttttgg gtcatccgac acataaactt tacctctaca
    33661 agaaatccat actatttctt tatatttatt aatcaaccta tattctaaat tgtgctcacc
    33721 tttttttcca tgtagtaatt cttgtatatc atctttccat atttgaacat catctggata
    33781 aacaatttta ctccaacaat tgaccaaatc agattctatc tctttactta agttaaattc
    33841 atcaaaaatt gctgaagaaa ttttaaattt attcctattt atatcccaaa aaaatatata
    33901 atcttctgta ctttgagata aaagttcaaa gaaaatttct atatggtcta aacttaaaga
    33961 gttcgattct tctctcatct tttcccccta caatattact attagtgtag tttaatcaac
    34021 aaaatatcct tatttagatt atactatttt actaattttt tgtctcatca aacacatttc
    34081 cccaacttta gttatcttat caaatctctt actcttaact aagttttttg agattcataa
    34141 agtaattttt ctataatcat tactggtgat ttatttttac ctgctaaaac accatgttaa
    34201 atcagttatt aaatcatttt ctcttaaaat tctatttttc gttatataaa gagttatcag
    34261 ttctttattc tataaaactt ttctattact cttgaattta ttttattttt ttctccgcct
    34321 attctctttg gatttggtat tgtttttcta tagattttgg caaagaagtg tctcttccta
    34381 taatataaga ttttgatatt tcttcatcat ctataaattt tttaataggg attatatcat
    34441 tttttatatt tatttatata aatatttttt gtttttaatt ttttctatct tcttatgtac
    34501 ttacatttaa tttattcttt tcagttaata aaataggtac atttttagta catgaaaata
    34561 gagttgctta cagggtatat aggattgatg tactatttgc taatattaca ttttcaactg
    34621 attcaacccc tcttttactt acataattta agtatatttt tctggatttt taaatttatg
    34681 tactttaaaa tggatatact tattttcatt gattttgtaa gaattaataa aaaatacgat
    34741 tacactacaa aattagaatg tcaatgttta taaatataaa ataatatttt ttattttaat
    34801 tattacatcc atagtttcca tttgttataa aaaagttact atttattgaa aatttagata
    34861 tttttctaaa aattatctat gttaatagtt aaatttatga acattttttg tttttatgtt
    34921 aggatatttc ttagaaatga aatacttctt aatttgattt gatatgtata tttttatagc
    34981 tattt
//
LOCUS       DAJMZY010000033        34499 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.033, whole genome shotgun sequence.
ACCESSION   DAJMZY010000033 DAJMZY010000000
VERSION     DAJMZY010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 34499)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34499)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34499
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.033"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            complement(8..664)
                     /locus_tag="OE968_001574"
     CDS             complement(8..664)
                     /locus_tag="OE968_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HCP7218856.1"
                     /translation="MELQDTIFKRQSVRKFKNQDVSDEDILKMIKAAGAAPSGKNIQN
                     WHFVVIKRRDLMEKIADVITKKQQEILVEMDKVSVDKANRFRKFVKNFTLFYLKAPVL
                     VLVFTKVYNPSGYYELELIDAPKETIDKLFIRNPGMQSLGAAIENFTLSAIELGYGSC
                     WLTSQNYAADEIEAVLEAETGFEKGEYFLGAMLALGVPEDNLKSPSKKPVEEICTFIK
                     "
     gene            complement(719..1348)
                     /locus_tag="OE968_001575"
     CDS             complement(719..1348)
                     /locus_tag="OE968_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HCP7218857.1"
                     /translation="MVDSIIFDLDGTLWDSTEEVCKVWQDVLSEHKEIELSVTKDLFR
                     SLMGLSFEEIANRLFPNLSEEERMNLLNECSLKECDYLSENGAKLFDDIEDTLKLLSK
                     KYKLFIVSNCQAGYIESFLKAHKLEQYFIDFECPGNTGLHKGENNKLIIERNKLINPI
                     YVGDTQGDANSAKFVGIPFIYAKYGFGNVDVYDYFIDSFKDLLEHDILK"
     gene            complement(1479..2120)
                     /locus_tag="OE968_001576"
     CDS             complement(1479..2120)
                     /locus_tag="OE968_001576"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HCP7218858.1"
                     /translation="MKICIVLNGEIEDYEVTRDIIIKECYDCIICADGGANHTYKMEI
                     MPDYILGDLDSVEEEKINFYKNKGVKFEKFPSKKDETDTELCLFLAKTLKANHIDFFG
                     ALGGRIDHTLANIKLLYYLKEDGIYSRILSDKEEMYIVENEEISLYGNPGDTISVIAI
                     NGDAKGVTLTGLEYPLDNYYMKYSVPIGISNVMLSNSCKIKVEQGCVLVVRNL"
     gene            complement(2129..2800)
                     /locus_tag="OE968_001577"
     CDS             complement(2129..2800)
                     /locus_tag="OE968_001577"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HCP7218859.1"
                     /translation="MIKLAPSILSADFAKLLEDVRKVESAGCEYLHIDVMDGHFVPNI
                     TLGPLVVKSLKKENINMVFDAHLMIENPDQYIEEFVKAGCDIITVHQEACVHLHRTIQ
                     NIKSHGIKAGVVLNPATPVDTIKHVLSDLDMVLLMSVNPGFGGQSFIPCVLDKIKELK
                     AIIDSQGLNIDIEVDGGISPKNVAEVVQAGANVIVAGSAIFGSDDIQETVNLFRKNAS
                     LEELV"
     gene            complement(2805..3689)
                     /gene="rsgA"
                     /locus_tag="OE968_001578"
     CDS             complement(2805..3689)
                     /gene="rsgA"
                     /locus_tag="OE968_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HCP7218860.1"
                     /translation="MLEGKIIKGISGFYYVDTYNGIYECKARGIFRKQKITPLVGDRV
                     KISIVDEDEKKGILEEIDSRDTELIRPPIANVDKALIVFAIKNPKPNLSLLDRFIVLA
                     EKENLETVIILTKADLDDNDTLETVKNIYELSGYKVIPVSNITKLNIDKVKEELKENV
                     VVFAGPSGVGKSSLLNEIDENFKLQTGVVSDKIKRGKHTTRHAELLKLEFGGMVADTP
                     GFSSLALEDIEEVELKDYFIEFDKFNDCKFGSKCIHENEPNCAIKEAVTNGEISKERY
                     DSYIQLLHEIRQNNSRRY"
     gene            complement(3787..4524)
                     /locus_tag="OE968_001579"
     CDS             complement(3787..4524)
                     /locus_tag="OE968_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HCP7218861.1"
                     /translation="MKKKTVLITGGARGIGKAMSKAFAKEGYNVLVNFNKSENEAKEL
                     YTILNEKNFSVKLFKANISNREDVEDMVDYCIKEFGGLDVLVNNAGVSQDKLFTDITD
                     EDWDNMMNINLKGSFYCSQVALKYMISEKKGNIINISSIWGISGASCEVHYSITKAGI
                     IGMTKALAKEVGPSNIRVNSIAPGVINTDMLSGYNEEDIDALVEETPLMRLGTPEDIA
                     NCAIFLASDKSNFITGQVISPNGGFVI"
     gene            complement(4632..6647)
                     /gene="pknB"
                     /locus_tag="OE968_001580"
     CDS             complement(4632..6647)
                     /gene="pknB"
                     /locus_tag="OE968_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HCP7218862.1"
                     /translation="MGDTILGNRYEIIRKIGDGGMAFVYEAKDRLLNRTVALKVLRPE
                     FVDDDEFLTKFKREAEAVASLSHPNIVNVYDVGEDGKVHYIVMEFVDGKNLKEIIQDE
                     GILDEYTALDITKQIAMALSAAHKKGIIHRDIKPHNILISNEGRVVKVADFGIAKAVS
                     NSTMTNIGSIIGSVHYFSPEQAKGKFVTNNADLYSLGIVLYEMLIGKVPFRGDSPISI
                     ALQHINDDIDFTSEEKVRIPQSVRTTIKKLTEKSSADRYQTAEELIEDIEYIEKNIDL
                     DFIKEYDDFATKKIDEKEINKVVNPTLAKPAPEKVVKPVEVADLDDDEDYYDDFYEED
                     DDEDEEEEEIMRAKKNQRPKSTPSKRTKKKKKKQESPKSRRRLKVIAAVLILILCAQV
                     FLAYKFLFAGGFGNKSLTVPNLVNMTLEEAQSAVEKEGLYLSVKSEEYNSEVDENCII
                     SQTPEGGSTNVKKGDTINVVVSKGSSQASVPNVVGLTLSNAKQLIEENNLKVGTVKYE
                     YSSIYKEGTVLSQSPGAGSSRAQEGDEVNLYVSKGSEKSNTQTPTVPDKKPTTPENNT
                     PTEPGSNSGNSGGNSGGSNSGNSGGNSGNNGSNSGGSNSGNSGGNSGGSNSGDNGGSS
                     GGSNSGDNGGSSGGSNSGDNGDSSGGSNSGDNGGTSSGTGANIGKTE"
     gene            complement(6664..7416)
                     /locus_tag="OE968_001581"
     CDS             complement(6664..7416)
                     /locus_tag="OE968_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HCP7218863.1"
                     /translation="MVYSCASHIGKIRKNNEDYCEGEVIDTEHGPIGIFAIADGMGGH
                     KKGEVASKLAVENIIDFLKENLLQHDNVKIDYIDDILKQAYNNVNSIVHKKSMEDIEF
                     EGMGTTLVTAIVYNNVLYVANVGDSRCYLLTDEKFDKITIDHSVVEELMMAHVITEEE
                     ARRHPQRNRITRAIGTDDMVVVDIFKKEIKKSDIILLATDGLTGFIDDEDIRDLILDY
                     EYERTSNISEELISMANDVSGKDNVSVIVIKV"
     gene            complement(7436..8467)
                     /gene="rlmN"
                     /locus_tag="OE968_001582"
     CDS             complement(7436..8467)
                     /gene="rlmN"
                     /locus_tag="OE968_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HCP7218864.1"
                     /translation="MEKKKIVLKNFTEDELKEFMKTIDEKPFRGSQIFSWIYKGAKTF
                     DDMNNIPKSLRNKLEEVSCIGHIDIELKLESKVDNTKKYLFLLDDGNIIETVMMDYDS
                     RVTVCVSNQVGCRMGCNFCASTMDGLIRNLEPWEILDQVIKIQEDTGKRVSNLVLMGS
                     GEPLDNFENTKQFLKIINEKNGLNIGYRHITLSTCGIVPKMYELADLEIAINLALSLH
                     SPYDEERRKIMPVANAYSIEEILNACRYYIKKTNRRVTFEYSLIKGVNDSEKEAKALA
                     KLLKGMLCHVNLIPINKVEEREYEKPDKAFIYKFRDSLEKNNIPATVRMSMGSDISGA
                     CGQLRRKYK"
     gene            complement(8475..9800)
                     /gene="rsmB"
                     /locus_tag="OE968_001583"
     CDS             complement(8475..9800)
                     /gene="rsmB"
                     /locus_tag="OE968_001583"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HCP7218865.1"
                     /translation="MDAREVGFKVLCDIEKNDNYSNIAINKHFKNLEISDMDRGLATE
                     LIYGVIENKYYLDYIINKLSKIKVKKMSTYVKIFLRMGTYQILFLDSISDYAAVNETV
                     KLSKKYDKKSSGFINAILRNEIRAKETIMDITEEDSVKYLSIKYSYNSWIIKNWIDKF
                     GQEFAEDLLEANNEKPSIYIRTNTLKISREELIEKLSEMGIVCLKVPMVEEAIKVEKM
                     KNIEKNELFKAGLFTIQDISSMIVGKVINPKEGSFVLDVCSAPGGKSTHLATLMNNTG
                     QVVARDIFEHKLKLINSTVNRLGLKNVFVERFDASEIDENSISKFDYVLADVPCSGFG
                     IIRRKPEIKYKKEEELKDITSIQKKILENASKYVKVGGTLVYSTCTIQDVENINIVTS
                     FVEENHNFEFVPIDTVNVDLDNQDKGYLKIYPNIHGIDGFFIAKLKRIR"
     gene            complement(9862..10563)
                     /locus_tag="OE968_001584"
     CDS             complement(9862..10563)
                     /locus_tag="OE968_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HCP7218866.1"
                     /translation="MYPVYGGFWGFDPTMVVLIPAILLTIYAQFKVSSTTNKYLRVNT
                     RRGYTGEQTARRVLDSNGLYDVKIEMVRGHLSDHYDPRRKAVRLSEDVYYGTSITSVA
                     VAAHECGHAIQHAKGYAPLQIRSSLVPVVNFASSISWFLIFLGFIMAGPFLKIGILLF
                     SASVLFQIITLPVEFNASSRAIVQLGNLGIIDESESRQSRRVLSAAALTYVAAALVSI
                     LQLLRLLLIAQRRND"
     gene            complement(10632..11384)
                     /locus_tag="OE968_001585"
     CDS             complement(10632..11384)
                     /locus_tag="OE968_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF116 domain-containing protein"
                     /protein_id="HCP7218867.1"
                     /translation="MTDIKKYLTSVGILILILGILIGVVNFFIISLTQIFSLMINIII
                     ISLILIILCSTVVTYRVIKGKYVNSNIMKINFNIVSGLFPIISFIASSFGMSKSDIRR
                     IYIKLNNEYIYSNKYNFNPEDIIILIPHCIQENSCKLKVTNDIDNCKECGRCNIGELI
                     KLKEKTNVKIFVATGGTLARKIIMDTKPKAVVAVACERDLTSGIQDIKKIPVLGVFNK
                     RPNGPCVNTNVDMMDIEKAIGFLTGKNILVCN"
     gene            complement(11394..12323)
                     /locus_tag="OE968_001586"
     CDS             complement(11394..12323)
                     /locus_tag="OE968_001586"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HCP7218868.1"
                     /translation="MKIVFMGTPDIAVPCLQKIIDEKYEILGVVTQPDKPKGRGKKLG
                     MSPVKELAIENNIPVYQPVKARDKEFIDKIKSLNPDVIVVVAFGQILPKEILEIPKLG
                     CINVHVSLLPKYRGAAPINWVIINGEEKTGVTTMYMDEGLDTGDMILKTEVNLDENIT
                     AGELHDKMMNIGAETLKETLRLIEEGNAPREVQNHEEFSYAPIMNKSLGNIDFSKSAR
                     EIHNLVRGVNPWPSAYTTYNDVIMKVWKTKVLDEKSTKDVGTIIDVSKDGIKVSTIDN
                     VLLIEEIQMPNKKRMLVGEYIKGNTIETGLVLG"
     gene            complement(12338..12778)
                     /gene="def"
                     /locus_tag="OE968_001587"
     CDS             complement(12338..12778)
                     /gene="def"
                     /locus_tag="OE968_001587"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HCP7218869.1"
                     /translation="MALRQIVQIGEPVLRKKSKKVEKIDEKIIQLLDDMAETMYDADG
                     VGLAAPQVGILKRVVVIDIGEELIELINPEIIETSGEQIDEEGCLSVVGEAGNVRRPN
                     YVKVRALNRNGETIELEGEELLARAFCHEIDHLDGILFVDKIEK"
     gene            complement(12796..15321)
                     /gene="priA"
                     /locus_tag="OE968_001588"
     CDS             complement(12796..15321)
                     /gene="priA"
                     /locus_tag="OE968_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HCP7218870.1"
                     /translation="MNNILNLSRGFIMKKYAKVIVRSNTIYTDNLFTYQIPVFLSDVI
                     KIGHRILVPFGKGNKPTEAFVFQFTDSLDEKIKIKEIIDILDENPIFRKEDLELVYWM
                     KNRYLCTYIECINLIYPKGYKLNNYKVVLLGESLSGLNDIELKEKISTLSDKNREIVE
                     KVIDSKGKIKVDKLKYIPNLNSSLYTMNKNGIIKLCWEYKNHKNEKKVCYISLSLESD
                     KIDDYIEQNKINVGSKQKEILSFLKNNENVEINDLLDLLNASKQSINSLSKKKLITLE
                     FKDYYREPKSIYKSVLKSIKLNNEQQEAVDEIKSNMFVDDKKPYLIHGVTGSGKTEVY
                     MEIIEFALNQGLDSIFLVPEIALTPQTIDRLKSRFGDLVGVFHSKLSEGEKHDVYKAV
                     KAGKVRVLIGARSALFAPFNSLGLIIIDECHESSYKSEKNPKFNAIEVARFMALKNNI
                     TLILGSATPSIEEYYRAKSGEYKLINIKSRANDKPLPNIEVVDMKDELDKGNRSIFSL
                     KLQKEIRYAIEENNQVILFLNRRGYANFVSCRKCGYVFQCENCDISLTYHKKSNTGRC
                     HYCGYEKEIPKECPECKSTYVKPFGVGTQKIEEELKYIFPDIKTLRMDKDTTSKKGAL
                     DEILNKFKDKEADVLIGTQMLSKGLDFENVTLVGILSADMILNFPDFKSFETTFQLIT
                     QVSGRAGRADKEGKVVLQTYDTEHYAIKHAIEYDYEGFYEDEIKIRKAFGYSPFNNML
                     SVVVSGEDERLVIKNIKNMHASLIYLLEKRGINDLGFILGPNPCSISKINQNYRWQIL
                     FKDENIEINLLKGIIKYICITKRDLIFDKNINVSIDINPNSVL"
     gene            complement(15560..16759)
                     /gene="coaBC"
                     /locus_tag="OE968_001589"
     CDS             complement(15560..16759)
                     /gene="coaBC"
                     /locus_tag="OE968_001589"
                     /EC_number="4.1.1.36"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional phosphopantothenoylcysteine
                     decarboxylase/phosphopantothenate--cysteine ligase CoaBC"
                     /protein_id="HCP7218871.1"
                     /translation="MLKDKTVVIGISGGIAAYKACDVVSKLKKLNANIHVIMTKSATE
                     FVKPLTFQSLSQNYVVEDMFEEPKTWEVEHISLAKKADLFLIVPASANVIGKIANGIA
                     DDMLTTTVMATKAQVLIAPAMNTNMYENPIVQKNIQTLKSFGYKFIEPESGRLACGDI
                     GTGKLANPDIIVEEVLTNLTKEQDLKGQSMIVTAGPTVESIDPVRYLTNRSSGKMGYS
                     IAREAIARGADVTLISGPTNLSIPQNLKKFVQIESAQDLYEAVVSNLSENKIVIQSAA
                     VADYKPKTYSDKKIKKKNDDLSIELSRNYDIAYEIGKIKEDKILIGFAAETNDLIEHA
                     KGKIKKKNLDFIVANDLTKEGAGFRADTNIVKIIDVEGNITEYPKMKKEEVANVILDK
                     VKALLEK"
     gene            complement(16764..17030)
                     /locus_tag="OE968_001590"
     CDS             complement(16764..17030)
                     /locus_tag="OE968_001590"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HCP7218872.1"
                     /translation="MLKPSINEVLEKIDNRYYLVGTVSKRARKLIDGEEPYVSNKTKE
                     KPVCVATKEVASGKITYRLLTEEEIEIEEARHHAEQHQQISEEE"
     gene            complement(17033..17650)
                     /gene="gmk"
                     /locus_tag="OE968_001591"
     CDS             complement(17033..17650)
                     /gene="gmk"
                     /locus_tag="OE968_001591"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HCP7218873.1"
                     /translation="MFVKKGLLLVVSGPSGAGKGTICKELLKENDTIKLSVSATTRKP
                     RTGEVDGVNYFFISKEKFEEMIEKGEFLEYAQIYDNFYGTPKAAIMECLEKGQDVLLE
                     IEMQGAKQIKEVCPEGVFIFVLPPSLEELKNRIVGRGTETEAEIEKRFSCAYEEIKMI
                     KDYDYFIFNEDVKTSAKEIEGIISSEKNKVSRYKNIIIEKFKEEL"
     gene            complement(17680..18561)
                     /locus_tag="OE968_001592"
     CDS             complement(17680..18561)
                     /locus_tag="OE968_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YicC family protein"
                     /protein_id="HCP7218874.1"
                     /translation="MAISMTGFGRGEYKDDNYYFLVECKTINHKYSDINIRLPRKISF
                     LEDKVRNLVKNYVKRGRVDLYIKFDLLGKEDVNLNFDEGLASQYIDILKEIKNKFDII
                     DDISVMNVAKFPDIVKIEEKEEDEDLLWSMLNQAVEDALIKLREMRSEEGKKLAEDIA
                     MRCDLLKNHIEEIEKYSSSVVEDYREKLNLRISELLDDPSIIDENRLAQEVAIYADKS
                     SITEEIVRFKSHIGQLKNTIFKDDSIGRKIDFLIQEMNRETNTIGSKSSDINITNLVV
                     EVKSELEKIREQIQNIE"
     gene            complement(18565..19395)
                     /locus_tag="OE968_001593"
     CDS             complement(18565..19395)
                     /locus_tag="OE968_001593"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HCP7218875.1"
                     /translation="MKFWKLHGIGNDFIAIDGRFDQINPSDYTALAKKVCHRRFSVGA
                     DGLLVVKDSKVADVEMVYYNSDGSRAAMCGNGLRCFCKFVYDNCIVKKESFTVDTLDG
                     IKDIKVNLTNREINSIRVNMGKGSFIAKDVPVLTNKERFVQESIKVLDRELKVTSMLM
                     GVPHTVVIVDELDVDDVCKYGKEIENNKIFPEKTNVNFVKVEDKYNIHVYTWERGCGY
                     TLGCGTGMTASAIVCNLLNMVESSVNVTSQGGTVKIDVGDFSYMTGPAVKICEGILEV
                     "
     gene            complement(19682..20716)
                     /gene="ltaE"
                     /locus_tag="OE968_001594"
     CDS             complement(19682..20716)
                     /gene="ltaE"
                     /locus_tag="OE968_001594"
                     /EC_number="4.1.2.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low-specificity L-threonine aldolase"
                     /protein_id="HCP7218876.1"
                     /translation="MRFIDLRSDTVTMPTDEMREAMAKAPVGDSIFRDDPTVNKLEEL
                     AAAKVGKEDAIFLPSGTFGNQLALFTHCLRGQEIIIGKGYHIVTHEVGAPAVIAGVQL
                     RTIDEDESGALNPELVEKAIRRDDIHEPQTGLICVENAYSGGTVVSLDNLREIKKIAE
                     KHNLPVHLDGARLFNAALTLGVEAKEIAKCCDSVMFCVSKGLAAPMGSILAGNKEFIA
                     KARRKQKVMGGGMRQVGIVAAAGIIAIEKMTLRLNEDHENAKYLACELNKIDGIEVNN
                     VNPDISMVFFKMSEDIIKEDVLIKEFFERNIKINKMENGEYRFVTHVDITKEDLDYVL
                     KTLKELIGVC"
     gene            21012..22787
                     /locus_tag="OE968_001595"
     CDS             21012..22787
                     /locus_tag="OE968_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NFACT family protein"
                     /protein_id="HCP7218877.1"
                     /translation="MALDGLVIHSIVDELSSKLTGGKIDKIHQPEDDEVIFNIRNNKE
                     NFRLVLSASASNPRVYLTSNYQKENPLKAPMFCMLLRKYIQGGNIVEISQIGFERIIK
                     ISVESLDELKEKTVKNIMIEIMGRHSNIIITHGEENKIIDSIKRVPFSISRVRQVLPG
                     HDYSLPPEQNKLNPLDDISKDLFIKNLEELEGPIFKSIYSKFLGISPIIAKEICYRAG
                     VNQNAIIKDISDEQFDALHKVFCNLFNDINSNKYSPCIIIDKKVDKVVDFSCINLTLF
                     SDLSYINKDSMSRILEDFYRTKDIKDRINQRSSDLKKSISVKLDRLYNKLKKQEEELS
                     ESENADIYKIKGELITSYIYMVEKGMESIEVANFYDENCNDVTIELNKNLTPSENAQK
                     YFKKYNKMKHAKVEISHQISLNKEEIDYLENIILSIENCENLAELQDIKEELAKVGYI
                     KTQKKNSKKDTIPSTKPHEFVSSDGFKILVGKNNKQNDYLTLRLADNDDLWMHTKNIP
                     GSHVIIKCAGKEVPDNTVFEGAMLAAFFSKSKLSSQVPVDYTKRKNVKKPSGSKPGMV
                     IYETNSTIYVTPEEETVAKLKVKSE"
     gene            complement(23002..24654)
                     /locus_tag="OE968_001596"
     CDS             complement(23002..24654)
                     /locus_tag="OE968_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HCP7218878.1"
                     /translation="MLLVKVENLKKYYADKLILDIDKLEILENDKIGLVGSNGQGKTT
                     LLKAILGEIEIDEGYTYLTESYSYISQSENNIETCSHSKEKSLLNAPDKFEEHLSGGE
                     KVKLKIADALSNKKNIIIADEPTSNLDKKSIGVLEDMFKRHEGALLLISHDRRFLDEL
                     CTTILELEDGKLKAYKGNYTDYLMQKDEEVKRADFEYQEYVKEKKRLEKALLYKKALS
                     DGIRKTPKRMGNSEARLHKMGGQTNKKKLDSNVKAIKSRIDKLEVKNKPKVSKEMNIK
                     MQDGMEIISKNLVEVKDMTLKLENKLLLDNVSFKIKRGKKIALLGDNGCGKSTLIKEI
                     LADKNDNIKINNKVKVGYFDQNQSLLDEEKSVLYNTKVNSSFDESFIRINLSLFGFKG
                     DDVYKKVKVLSGGEKVKIALCKIILEDNNFLVFDEPTNYLDIKSMEALEKALINTDKT
                     MLIVSHDRVFVSHICNYIIEIKDAKIREFDCNYDEYTISRNKKTPSRENQIKKENLLV
                     LENRLTTVISMLSIEKDNLKKELYESEYNELLKQINKLKNSF"
     gene            complement(24953..26164)
                     /locus_tag="OE968_001597"
     CDS             complement(24953..26164)
                     /locus_tag="OE968_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HCP7218879.1"
                     /translation="MKKTIMSLQHLLAMFGATVLVPILTGFNPSVAIFCAGVGTLIFH
                     FCTEGKVPAFLGSSFAFIPVILAAKEAYGGDLAYAQGGIIVAGLIYIIMSIIVKVVGV
                     NKIKLYFPAQVTGAMIVVIGLNLLPTAFSMASANFVIAFITLAIAILTNKFGRGFIKQ
                     LGILIAVFSGYIICLILRLVDITTITEASLFAIPNFTVPKFSLGAIVIISPVVLAVFM
                     EHIGDMTTNGAVVGKNFIENPGLNRTLLGDGFATIVAGCLGGPANTTYGENTAVLAIT
                     KNYDPSILRRTAIFAILLACVGKFGGFLQSIPGSVMGGISIMLFSMITYVGLKTIRDS
                     SCVESKINILIIAVILLIGLGTTYLSNKGISVGIPITSTVKITGLSLAAIVGIVLNRI
                     LNNQDFKVEEE"
     gene            complement(26448..26981)
                     /gene="pyrR"
                     /locus_tag="OE968_001598"
     CDS             complement(26448..26981)
                     /gene="pyrR"
                     /locus_tag="OE968_001598"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001156491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HCP7218880.1"
                     /translation="MVEKAQLMDEKAIARAITRISHEIIERNKGVENLVLVGIKTRGV
                     PIANRISKKIEQIEGTKVDTGDIDITLYRDDLEKIHVEPVVKGTYLDFNVNDKTVVLV
                     DDVLYTGRTVRASLDAIIDIGRPKSIQLAVLVDRGHRELPIRADYVGKNVPTSRHEII
                     SVSLLEIDGEDSVTIKE"
     gene            complement(27341..28288)
                     /locus_tag="OE968_001599"
     CDS             complement(27341..28288)
                     /locus_tag="OE968_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HCP7218881.1"
                     /translation="MFYFLKVKVGDIMDEVKEFLVLEEEEEVRLDIYLAEQLGDMSRS
                     YIQKIIKDGKVKVNNKVEKARYLVKEEDNIVIEIPEPKVLEVLPQDIPIDIVYEDDDV
                     LIINKPQDMVVHPAPGNYENTLVNGILYHCKDKLSSINGVIRPGIVHRIDKDTSGLLM
                     IAKNNYAHNFLAEQLKEHTITREYEFICYGVVKEDKITVDKPIGRNPKDRLKMAVVKD
                     GKNAITHFEVVERFDKFTHMRARLETGRTHQIRVHALSINHPLLGDYVYGPKETKFKL
                     KGQTLHAKKLGFIHPTTKEYIEFNSELPEYFKEVIKKIK"
     gene            complement(28257..28703)
                     /gene="lspA"
                     /locus_tag="OE968_001600"
     CDS             complement(28257..28703)
                     /gene="lspA"
                     /locus_tag="OE968_001600"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HCP7218882.1"
                     /translation="MLYILIIILLIGLDQLSKIWVLNNLVDVSTIPIINNVFHLTYVE
                     NRGAAFGLLQNNQWIFIIVALLATVFGLYYLNTRKVHIFGRLGIILIISGALGNLIDR
                     VRLGFVVDYFDFRIIWEYVFNIADVFVVVGTVFLCIYVLFFESKSR"
     gene            complement(29013..29792)
                     /locus_tag="OE968_001601"
     CDS             complement(29013..29792)
                     /locus_tag="OE968_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HCP7218883.1"
                     /translation="MKKIIWGICICLLSIVGVYTYNHNTHNQDSSKEAYSLNDNIKDD
                     YEDVIIKKGNEDEKILALTFDDGPDEDFTPQVLDILKKNDVKATFFVVGEKVEYNKEL
                     LKRQYDEGHEIGNHTFTHINVAKNSYSSVEKEITDTQNIIKSVIGVEPKIFRPPYRAM
                     SKSVCDIIVSKGMNIILWSNLDPRDWSNPGVDAIINTILTKVQNGNIILLHDYNTKRN
                     DKSQTIQALEVVIPKLKERGYKFVTVSELIQHLDKNKQVQK"
     gene            complement(29847..30329)
                     /locus_tag="OE968_001602"
     CDS             complement(29847..30329)
                     /locus_tag="OE968_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraR/DksA C4-type zinc finger protein"
                     /protein_id="HCP7218884.1"
                     /translation="MDTKKYKDKLLKERENLTNLVEDMKDNTLFGDTTKHTSEKYSSG
                     ELSSYDNHIGDMGTDLYMQNMQNSLINHEEGRLYQIDLALSKIENGTYGICDLCHNQI
                     DLERLDILPDTSLCNDCAKKENNLLGDAMQNPDVEDSNFYSEDLTNLTDLNKNGILRD
                     "
     gene            complement(30595..32016)
                     /locus_tag="OE968_001603"
     CDS             complement(30595..32016)
                     /locus_tag="OE968_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon starvation protein A"
                     /protein_id="HCP7218885.1"
                     /translation="MVSFLGSIVVLIVGYFVYGTFVEKVFGTNDKNQTPAIACRDGVD
                     YVPMKWKRIFLIQFLNIAGLGPIFGAIQGALFGPSAFLWIVFGTIFAGGVHDFASGYL
                     SMKNKGTSASELVGLYLGNGAKIAMRIFSVILLVLVGVVFVTGPAGLLKTLTGVNAQI
                     WVGVIILYYIMATVLPIDKLIGKIYPLFGAALLIMAVGVAGGLIIKGYNIPNINLQNM
                     NPNGTPLFPYLFITIACGAISGFHATQSPLMARCVEKESEARPVFYGSMVAEGIIALV
                     WAAAAMSYFHGIPQLNVIFNDGGAATVVNTVSVGLMGPIGGALAILGVVACPITSGDT
                     AFRSARLTIADAMNYNQDAVKNRFLIALPLFAVGVALTFIDFNIIWRYFSWANQTLAM
                     IMLWTGSAYLVKANKNHYITTLPALFMTVVTFSYIMQAKEGFRLPVNISNGIGVIVAI
                     ILGLLFFKKAKHIKEQNNHKLAS"
     gene            complement(32162..32932)
                     /locus_tag="OE968_001604"
     CDS             complement(32162..32932)
                     /locus_tag="OE968_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001295458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCP7218886.1"
                     /translation="MRAIIVEDEFPARKELRYFIENKSGIEVVSEFTNGIEVLDFIQE
                     NKIDVIFLDINIPHLDGMLLAKTLNQFKSRPKIVFITAYESYAVDAFSLDVFDYILKP
                     YSEERIISMLNKLEKSEMSDIELFNVNSNLYKYKKEAVNQEIEEITHKISLWKGDKLV
                     VIDIDDIYYCEANERQTFIYTEKEKFILKEGISEVENLINDKTFFRTHRSYIVNLTKV
                     KEIIPWFNNTYILKLKNSDYEVTVSRSKVKEFRLLMHI"
     gene            complement(32937..34139)
                     /locus_tag="OE968_001605"
     CDS             complement(32937..34139)
                     /locus_tag="OE968_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HCP7218887.1"
                     /translation="MKTSILIALIEKTSLIVVLFLLITKLKIFKQIFQKEEYSFNDLV
                     CIALVFTFLAIFGTYSGINYMGSIVNTRIISIVSGGILFGPMVGITAGVFSGIHRYFM
                     DIGGITSVPCLLSSILAGVLSGFLYKRIPKQHRVMYGILVGMISESFTILLIYLISYP
                     HSLAIQIIGGIYLPLIVGQIGIGFVISIVEGIEKDKKDIEARNKAEIKALQRQINPHF
                     LFNSLNTIASFIRFSPDKARELIINLSTYLRYNLEYSDNLIDINKEIEQVKSFVEIEK
                     ARFGELLTVSYDIEDVNIKIPSLIIQPLVENAIIHGILESGRAGVVKISIKKLPYSLE
                     NTVRISIEDNGIGISEEIINNVYQDNMPENKIGLYNVHLRLKLMYGRGLNIRRIDNGT
                     LIVFYVKE"
BASE COUNT        10972 a         6344 c         3468 g        13715 t
ORIGIN      
        1 ttgactttta ttttataaat gtacatattt cttctactgg ttttttagat ggactcttca
       61 aattgtcctc tggcactcca agagctaaca ttgcacctaa aaaatactct cccttttcaa
      121 aaccagtttc tgcttctaaa acagcttcta tctcatctgc tgcatagttt tgacttgtca
      181 accaacaaga accatatcca agttcaattg ctgatagtgt aaagttttca attgcagcac
      241 ctagactctg catacctgga tttcttataa ataatttatc tatagtctcc ttaggtgcat
      301 ctataagctc taattcataa tatcctgatg gattatatac ctttgtaaaa actaatacta
      361 aaactggagc ttttaagtaa aatagtgtaa aatttttaac aaattttcta aatctattag
      421 ccttatccac tgatacttta tccatttcta caagtatttc ttgttgcttt ttagttatca
      481 catctgctat cttttccatt aaatcacggc gttttataac aacaaaatgc cagttttgaa
      541 tattcttgcc tgatggtgct gcacctgctg cttttatcat ttttaaaata tcttcatctg
      601 atacatcttg atttttaaac tttcttacac tttgtctttt aaaaatagta tcttgtaatt
      661 ccatttttaa atccccccat aactttttta ttattttaat ataattttta aactcatctt
      721 attttaatat atcatgttct aacaaatctt taaatgaatc tataaaataa tcatatacat
      781 ctacattccc aaacccatat ttggcatata taaaaggtat acctacaaac ttagcactat
      841 ttgcatcacc ttgcgtatca ccaacataga ttggatttat taatttattt ctttcaatta
      901 taagtttatt attttctcct ttatgcaaac cagtattacc aggacattca aaatctataa
      961 aatactgttc tagtttatgt gcttttaaaa aagattctat atatccagct tgacaattac
     1021 ttactataaa taatttatat tttttagata gtaatttaag agtatcttct atatcatcaa
     1081 ataatttagc tccattttca gataaatagt cacattcttt caaagaacat tcattcaata
     1141 aattcattct ttcttcttca cttaaatttg gaaataaacg atttgctatt tcctcaaaag
     1201 aaagccccat aagacttcta aataaatctt ttgtgacact taattctatt tccttatgct
     1261 cacttaaaac atcctgccag actttgcata cttcttcagt tgaatcccac aatgttccat
     1321 ctaaatcaaa aataatacta tctaccacaa aaaatccccc ttatgtcaaa gtttattata
     1381 tatttataat tatatactaa aaagcagata caatcataaa tatattttac ttgattgtat
     1441 ctgctctaca atataaaacc aattgtcaaa atcaaatttt ataaatttct aactacaagt
     1501 acacagcctt gctctacttt aatcttacaa gaattactca acataacatt tgatattcca
     1561 ataggtacag agtatttcat ataataatta tcgagagggt attctaagcc agtaagtgtt
     1621 acacccttag catcaccatt tatagctatt acagaaatag tgtcccctgg gtttccatac
     1681 aatgaaattt cctcattttc aactatatac atctcttctt tatcagaaag tatcctagaa
     1741 tatataccat cttcttttaa ataatataat agctttatat ttgcaagagt gtggtcaatc
     1801 cttcccccta aagcaccaaa aaaatcaata tgatttgctt taagtgtctt agctaaaaaa
     1861 agacaaagct ctgtatcagt ctcatctttt ttagatggaa atttttcaaa tttaacacct
     1921 ttatttttat agaagtttat cttttcttct tctactgaat ctaaatctcc taatatataa
     1981 tctggcatta tttccatttt ataagtgtga tttgcccctc catctgcaca tattatgcag
     2041 tcataacatt ccttaattat aatatctctt gtaacttcgt aatcttcaat ttcgccattt
     2101 aaaacaatac agattttcat tattaaattt aaactaattc ttcaagagaa gcattctttc
     2161 taaataaatt aactgtttct tgaatgtcat cacttccaaa tattgcagaa cctgctacta
     2221 ttacattagc tcctgcttgt acaacttcgg ctacgttttt agggcttata ccaccatcaa
     2281 cttctatatc aatgtttaat ccttgactat ctataatagc ttttaactct ttaatcttat
     2341 ctaaaacaca aggaataaat gattgtcctc caaatccagg gttaacagac attaataata
     2401 ccatatctaa atcagatagt acatgtttaa tcgtatctac tggtgtagct ggattaagta
     2461 ctacaccagc ttttattcca tgtgatttta tattttgtat agttctatgt agatgaacac
     2521 aagcctcctg gtgaacagtt attatatcac atcctgcttt tacaaattct tcaatatact
     2581 ggtctggatt ttctatcata agatgagcat caaataccat atttatattt tctttcttta
     2641 aacttttgac tacaagtggt cctaatgtaa tgtttggtac aaagtgtcca tccattacat
     2701 cgatatgaag atattcacat cctgcacttt ctacttttct tacatcttct aataattttg
     2761 caaaatctgc tgataatatt gatggtgcta atttaatcat gtttctaata cctcctacta
     2821 ttattttgtc ttatttcatg tagcagctgt atataactat catatctttc tttagatatt
     2881 tctccatttg taacagcttc ttttatagca caattaggtt cattttcatg aatacacttt
     2941 gaaccaaact tacaatcatt aaatttatca aattctataa aataatcttt aagttcaact
     3001 tcctctatat cttcaagtgc aagggaacta aaacctggtg tatctgcaac cattccacca
     3061 aattctaatt ttaaaagttc agcgtgacga gtagtatgtt ttcccctttt tattttatca
     3121 cttacaactc ctgtttgaag tttaaaattt tcatctattt catttaataa gcttgatttt
     3181 ccaactccag atggtcctgc aaacactact acattttctt ttaattcttc ttttacttta
     3241 tctatattta acttagtaat attgcttaca ggaatgactt tataaccact aagttcatat
     3301 atatttttaa cagtttctaa tgtatcatta tcatctaaat ctgcttttgt aaggattatt
     3361 acagtttcta aattttcttt ttctgccaaa actataaatc tatctaaaag agataagttt
     3421 ggtttaggat tttttattgc gaatactatt aatgctttat ctacatttgc aataggaggt
     3481 cttataagtt ctgtatctct actgtcgatt tcttctaaga tacccttttt ttcatcttca
     3541 tcaacaatgc ttattttgac tctatcacca accaaaggtg ttattttctg ctttctaaat
     3601 atccctctag ccttacattc ataaatacca ttataagtat ctacataata aaatccacta
     3661 atccccttta taatttttcc ttctagcatc aaatgcctcc ctttataaaa tttatataaa
     3721 cacatactgt ttatgagtag tatatcgtgt tattctttcc tatttttata taataccaca
     3781 ttttttttaa ataacaaatc ctccgtttgg actaattacc tgaccagtga taaaatttga
     3841 tttgtctgat gccaagaaaa tagcacaatt tgctatatct tctggagttc ctagcctcat
     3901 tagaggggtt tcttccacaa gagcgtctat atcttcctca ttatatccag ataacatgtc
     3961 agtattaatg acacctggag ctatgctatt tactctaata tttgatggtc ctacttcttt
     4021 agctaatgcc tttgtcatac ctattatacc tgcttttgtt atagaataat gcacttcaca
     4081 agacgcacct gatatacccc agattgaaga tatattaatt atatttcctt ttttttctga
     4141 tatcatgtat tttaaagcaa cttgtgaaca ataaaagctt ccttttaaat taatattcat
     4201 catattatcc caatcttcat cagttatatc tgtaaacaac ttatcttgac ttacaccagc
     4261 attgtttaca agtacatcca atcctccaaa ttcttttata caataatcta ccatatcctc
     4321 tacatcttct ctatttgaaa tattagcctt aaaaagtttt acagaaaaat ttttttcatt
     4381 taatatagtg tacaactctt tagcttcatt ttctgactta ttaaaattta ctaatacatt
     4441 gtaaccttct tttgcaaaag ctttagacat agctttacca atccctctag ctcctcctgt
     4501 aattaaaact gttttcttct tcataaatac ttttctcctt atattataac caattcagta
     4561 ttttatacaa aacaaactgc cctttaaaga aaatattttc tataaaagga cagctcttat
     4621 tttattaata tttattctgt tttaccaatg tttgcgccag ttcctgatga agttcctcca
     4681 ttatctcctg agtttgagcc tcctgaacta tctccattgt ctcctgagtt tgaacctcct
     4741 gaacttcctc cattgtctcc tgagtttgag cctcctgaac ttcctccatt atctcctgag
     4801 tttgagcctc ctgagtttcc accactattt cctgagtttg aacctcctga gttacttcca
     4861 ttattgcctg agtttccacc actatttcct gaatttgagc ctcctgaatt tccaccactg
     4921 tttcctgagt ttgaaccagg ttctgttggt gtattattct ctggtgttgt tggtttttta
     4981 tctggtactg ttggagtctg tgtatttgat ttttctgaac ctttgcttac atatagattt
     5041 acctcatcac cttcctgagc tcttgatgag ccagcacctg gactctgact taaaactgta
     5101 ccttctttat atattgagct gtattcatac ttaacagttc ccacttttaa gttattttct
     5161 tcaataagtt gttttgcatt actcaaagta agtcccacta cattaggaac agatgcctga
     5221 cttgaacctt tacttacgac aacatttata gtatcaccct ttttgacatt tgtacttcca
     5281 ccttcaggtg tctgtgatat tatacaattt tcatcaactt cactattata ctcttcactt
     5341 tttacactca ggtataatcc ttctttttca acagcacttt gagcttcttc taatgtcata
     5401 tttacaagat taggaacagt caaagattta ttgccaaacc ctccagcaaa taaaaactta
     5461 tatgctaaga atacttgagc acacaatatc agtatcaaaa cagccgcaat tacttttaat
     5521 cttcttctag attttgggct ttcctgtttt ttcttctttt tcttagttct cttacttgga
     5581 gtactcttag gtctctgatt ctttttagct ctcattatct cttcctcttc ttcatcttca
     5641 tcatcatctt cttcataaaa atcatcatag taatcttcat catcatccaa atcagctact
     5701 tcaacaggct taaccacttt ttcaggagct ggttttgcaa gtgttggatt tacaacttta
     5761 ttaatttctt tttcatcaat tttcttagtt gcaaaatcat catattcttt tataaaatct
     5821 aaatcaatat ttttttctat atactctata tcttctatca attcttcagc agtttgatat
     5881 ctatctgcac tagatttttc tgtaagcttt tttattgtag ttcttacact ttgaggaatc
     5941 ctaacttttt cttctgatgt aaagtctata tcatcattaa tgtgttgaag tgctatagaa
     6001 attggactat ctcccctaaa tggaactttt cctatcaaca tttcatataa aactatacct
     6061 agagaataca ggtcagcatt attagttaca aatttacctt tagcttgctc tggtgaaaaa
     6121 taatgcactg aacctattat actaccaata ttagtcattg ttgaatttga aacagctttg
     6181 gctataccaa aatcagccac ttttactact cttccttcat ttgatatgag aatattatga
     6241 ggttttatat ctctatgtat aatccccttt ttgtgcgctg cactaagtgc catagctatt
     6301 tgttttgtta tatctaatgc agtatattca tctaatatac cttcatcttg tataatctct
     6361 tttagattct tcccatctac aaactccatt acaatgtagt gaacttttcc atcttcacca
     6421 acatcataaa catttactat atttggatgt gaaagacttg ctactgcttc tgcctctctt
     6481 ttaaactttg ttagaaattc atcatcatct acaaattcag gtctaagtac tttaagtgca
     6541 acagtcctgt ttaataatct gtctttagcc tcatatacaa atgccattcc tccatcacca
     6601 atcttcctga tgatttcata tcgatttcct aaaattgtat ctcccacaat atcaccgtcc
     6661 taattatact tttatcacta taaccgaaac attatcttta ccagaaacat cattggccat
     6721 acttatcaat tcttcactta tattactagt tctctcatat tcataatcta atattaaatc
     6781 tcttatatct tcatcatcaa taaacccagt taatccatct gtcgcaagaa gtattatatc
     6841 actttttttg atttctttct taaaaatatc tacaacaacc atatcatctg ttccaattgc
     6901 tctagttatt ctattcctct gtggatgtct tcttgcctct tcttctgtaa tgacatgggc
     6961 catcataagt tcttcaacca cggaatggtc tatagttatt ttatcaaatt tttcatctgt
     7021 taacaaataa catctgctat ctccaacatt tgccacatat aagacattat tatacactat
     7081 agccgtaact aatgtagttc ccattccttc aaattctata tcttccatag attttttgtg
     7141 cacaattgag tttacattat tataagcctg ttttaatata tcatctatat agtctatttt
     7201 tacattatca tgttgtaata agttttcctt tagaaaatca attatatttt ctactgctaa
     7261 tttactggcg acttcacctt ttttatgtcc acccattcca tcagctatgg caaatattcc
     7321 tattggacca tgttctgtat ctataacttc tccctcacaa tagtcttcat tgttttttct
     7381 tatttttcct atatgggagg cacaactata aaccatacga cttcctcctt acaaattact
     7441 tgtattttct tctcaattgc ccacaagctc cactaatatc agaacccata gacatcctaa
     7501 ctgtggcagg tatattgttc ttctccaaac tatccctaaa tttataaata aatgctttat
     7561 ctggcttttc atattctctt tcttcaactt tatttattgg aattaaattt acatgacata
     7621 gcataccttt taggagctta gctaatgcct ttgcttcttt ttctgagtca tttacccctt
     7681 ttataagaga atattcaaat gtaacccttc tatttgtctt ttttatataa tatctacatg
     7741 cattcaatat ttcttcaata gaataagcat ttgctacagg cataattttt cttcgttctt
     7801 catcatatgg tgaatgaagt gataaagcta aatttatagc tatttctaag tctgccaact
     7861 catacatttt aggtactatt ccacaagttg aaagagttat atgcctatac cctatattaa
     7921 gaccattttt ttcgttaatt atttttaaaa attgttttgt attttcaaag ttatcaagtg
     7981 gctcaccact ccccatcaat acaagatttg ataccctctt accagtatct tcttgaattt
     8041 taataacttg gtctaaaatt tcccatggct ctaagtttct aattaatcca tccattgtag
     8101 atgcacaaaa attacatccc atcctacaac ctacttggtt agaaacacag acagtaactc
     8161 tactatcata atccatcatc acagtttcta ttatatttcc atcatctaat aaaaacaaat
     8221 atttttttgt attatctacc ttagattcta actttaattc tatatctata tgccctatac
     8281 atgaaacctc ttctaattta tttctcaaac tttttggtat attgttcata tcatcaaaag
     8341 tttttgcacc cttatatatc caagagaata tttgacttcc tctaaagggc ttttcatcta
     8401 tagttttcat aaattcttta agttcatctt cagtaaaatt ttttaatact atctttttct
     8461 tttccattct ctcactacct tattctcttt aattttgcta tgaaaaaacc atctatacca
     8521 tgaatattag gatatatctt taaatatcct ttatcttgat tgtctaagtc tacatttact
     8581 gtatcaattg gaacaaattc aaagttgtga ttttcttcaa caaaagaagt aactatattt
     8641 atattctcca catcttgaat tgtacatgta ctatatacta aagttccacc aactttgaca
     8701 tatttagatg cattttctaa aattttcttt tgtatagaag tgatgtcttt taactcttct
     8761 tctttcttat acttaatttc tggtttacgt cttattatac caaaaccaga gcaaggaaca
     8821 tctgctaaaa cataatcaaa tttacttata ctattttcat caatctcaga agcatcaaat
     8881 ctttctacaa acacattttt aagccccaat ctatttacag tagagtttat aagctttagt
     8941 ttatgctcaa aaatatctct agctactact tgaccagtat tgttcattaa agtagctaag
     9001 tgagtagatt tccctccagg agcactacat acatccaaaa caaatgagcc ttcttttgga
     9061 ttaattactt tccctactat catagaactt atatcttgaa ttgtaaataa accagcctta
     9121 aataattcat ttttttctat atttttcatt ttttcgactt taatagcttc ttctaccata
     9181 ggaactttta aacatacaat acccatttca cttaattttt caataagttc ttctctactt
     9241 attttaagtg tattcgttct tatatagata ctaggctttt cattatttgc ttccaacaaa
     9301 tcttcagcaa attcttgtcc aaatttatct atccagtttt ttataatcca agagttatag
     9361 gaatacttta tagataagta ttttacacta tcttcctcag ttatgtccat tatagtctct
     9421 ttagctctta tttcatttct aagaatagca tttatgaaac cagaagattt tttatcatat
     9481 ttcttagata attttacagt ttcattaact gctgcataat ctgatatact atctaaaaat
     9541 aaaatctgat atgttcccat tcttaaaaag attttaacat aagttgacat tttttttacc
     9601 tttatttttg aaagtttatt gattatataa tctaaataat atttattttc tattactcca
     9661 taaattaact ctgttgcaag tcctctatcc atatcactta tttctaaatt tttaaaatgc
     9721 ttatttattg caatatttga ataattgtca tttttttcta tatcacataa tactttaaat
     9781 ccaacttctc ttgcatccat ataaatttct cccttttatt aaacataaaa aagggttgtt
     9841 tctaaacaac ccactttact tttagtcatt tcttctttga gctattagta acaatctaag
     9901 taattgaagt attgaaacca atgctgctgc aacatatgtt aaagctgctg ctgaaagtac
     9961 tcttctactt tgtcttgact cactttcatc tataatacct aaattcccaa gttgaacgat
    10021 tgctctactt gaagcattaa attctacagg caatgttatt atttggaata acactgaagc
    10081 cgaaaacaat agtataccaa tttttaaaaa tggaccagcc ataataaatc ctaaaaatat
    10141 taaaaaccaa gatatacttg aagcaaaatt cactactggt actaaactac ttcttatttg
    10201 aagaggtgca taacctttag catgttgtat ggcatgacca cattcatgtg cagctactgc
    10261 aacagaagtt atagatgttc cataatatac atcttctgac aaccttacag cctttcttct
    10321 tgggtcataa tggtcactta gatgccctct aaccatttct atctttacat catacaaacc
    10381 atttgaatca agtactcttc ttgctgtttg ctctccagta tatcctcgac gtgtatttac
    10441 tcttaaatac ttatttgttg ttgaactcac tttaaattgt gcatatatag taagtaatat
    10501 agctggaatt aatacaacca ttgttgggtc aaatccccaa aaaccgccat atacagggta
    10561 cataaataac actctcctaa aatatatttt tattatacat cctcttaata ttcacttaac
    10621 ttaaaaacag tttaattaca aactaatata ttttttcctg ttaaaaagcc tatagctttt
    10681 tcaatatcca tcatgtctac attagtattt acacaaggtc cattaggtct tttgttaaat
    10741 acacctaaaa caggaatttt cttaatatct tgtattccag atgtcaaatc tctttcacat
    10801 gcaacagcta caacagcttt aggtttagtg tccattataa tttttctagc tagagttcct
    10861 cctgtagcta caaatatttt tacattagtt ttttccttta gcttaattaa ttctcctatg
    10921 ttgcatcttc cacattcttt acaattatct atatcattag taacttttaa tttacaacta
    10981 ttctcttgaa tacaatgagg tattaaaatt attatatcct ctggattaaa attatattta
    11041 ttactgtata tatattcatt atttaacttt atatatattc ttctaatatc actttttgac
    11101 ataccaaatg atgatgcaat gaaagatata ataggaaata atccactgac aatattaaaa
    11161 tttattttca ttatatttga gttaacatac tttcctttaa ttactctata agtaactact
    11221 gttgaacata gtattataag tattagtgat attattataa tatttatcat caaggagaat
    11281 atttgagtta aacttattat aaaaaaatta acaactccta tcaaaattcc taatattaaa
    11341 atcaaaatcc caacacttgt taaatacttc tttatatctg tcatactttt cacctaaccc
    11401 aatactaaac cagtttctat agtattccct tttatatatt caccaaccaa cattctcttt
    11461 ttattcggca tctgaatttc ttcaattaaa agtacattat ctatagtact tacttttatc
    11521 ccatctttgc ttacatcaat tattgtacct acatcttttg tgcttttttc atctaacact
    11581 ttagttttcc aaactttcat tatgacatca ttataggtag tataagcact tggccatgga
    11641 tttactcctc taactaaatt gtgtatttct ctggcacttt ttgaaaaatc tatgttacct
    11701 aatgatttat tcattattgg cgcataggaa aattcttcat gattttgtac ttctcttgga
    11761 gcatttcctt cttcaattaa tcttaatgtt tcttttaaag tttctgctcc tatattcatc
    11821 attttatcat gaagttctcc tgctgttata ttttcatcaa gatttacttc tgtctttagt
    11881 atcatatctc cagtatctaa tccttcatcc atatacatag ttgtaacacc agtcttttct
    11941 tcaccattta ttattaccca atttataggt gccgcacctc tatattttgg aagtaaagaa
    12001 acatgaacat ttatacatcc aagtttagga atctctaata tttcttttgg aagtatctgt
    12061 ccaaaagcta caactactat tacatctgga tttaaagatt taattttatc tataaattct
    12121 ttatctctag cctttactgg ttgatataca ggtatattat tttcaattgc cagttctttt
    12181 actggactca tacctagttt tttacctctt ccttttggtt tatctggttg agttacaaca
    12241 cccaatattt catacttctc atctattatt ttttgtaaac atggaactgc tatatcagga
    12301 gttcccataa atactatttt catcaaatca actcctacta cttttctatt ttgtcaacaa
    12361 ataaaattcc atctaagtgg tctatctcat gacaaaatgc tctagctaaa agttcttctc
    12421 cctctaactc tattgtttca ccatttctat ttaaagctct gacctttaca taatttggtc
    12481 ttctaacatt tcccgcttct ccaacaacac ttaaacatcc ttcctcatct atttgctccc
    12541 cagatgtttc tattatttca ggatttataa gttctataag ctcttctcca atatctatta
    12601 ctactactct ttttaatatt ccaacttgag gtgcagccag tccaacacca tctgcatcat
    12661 acatagtttc tgccatatca tctaataatt gtattatctt ttcatcaatt ttttcaacct
    12721 tttttgattt ttttcttaat actggttctc ctatttgaac tatttgtctt aaagccatta
    12781 taattcctcc taaatttata atacactgtt tggattaata tctatagata cattgatatt
    12841 cttatcaaat atcaaatctc gttttgttat acatatatat tttattatac cctttaagag
    12901 attaatttca atattttcat ctttaaagag tatttgccat ctataatttt gatttatttt
    12961 tgatattgaa catggatttg gacctaatat aaatcctaaa tcatttatac cccttttttc
    13021 taataaataa atcaatgatg catgcatatt ttttatattt tttatcacta atctttcatc
    13081 ttcaccacta acaactacac ttaacatatt attaaaagga gaatatccaa atgcttttct
    13141 tatttttatc tcatcttcat aaaaaccctc ataatcatat tcaatagcat gcttaatagc
    13201 atagtgttca gtgtcataag tctgaagtac tacttttccc tctttatcag ctctccctgc
    13261 tcttccagag acttgagtta tcaattgaaa tgtagtttca aaacttttaa agtctggaaa
    13321 atttaatatc atgtctgcag acaaaatacc tactaaagtt acattctcaa aatccagccc
    13381 tttacttaac atctgtgttc caataagtac atctgcttct ttatctttaa atttatttag
    13441 tatctcatct aaagcacctt tttttgaagt tgtatcttta tccattctca aagtttttat
    13501 atctggaaaa atatatttta attcctcttc aattttttga gttccaactc caaatggctt
    13561 aacataagta cttttacatt caggacactc ttttggaatt tctttctcat atccacaata
    13621 gtggcatctt ccagtattgc ttttcttatg ataagttaaa gatatatcac aattttcaca
    13681 ttgaaacaca tatccacact ttctacaaga tacaaaattt gcataacctc ttctgtttaa
    13741 aaatagtatt acttgattat tttcttcaat cgcataacgt atttcttttt gtaatttcaa
    13801 actaaatata cttctatttc ctttatctaa ctcatctttc atgtctacaa cttcaatgtt
    13861 tggaagaggc ttatcatttg ctctactttt tatatttata agtttgtatt ctccagattt
    13921 tgccctataa tactcttcaa ttgagggcgt tgctgaacct aaaataagag ttatattatt
    13981 ttttaatgcc ataaatctag caacttctat agcattaaat tttggattct tctcagactt
    14041 atatgatgac tcatgacatt catcaattat tattaagcct aaggaattaa aaggtgcaaa
    14101 taaagctgac ctagctccaa ttaacactct tactttacct gctttgacag ctttgtaaac
    14161 gtcatgtttt tctccttcag atagtttact gtggaacact ccaactaaat ctccaaacct
    14221 actctttagc ctatctattg tttgaggagt taatgctatc tcaggtacta agaatatact
    14281 gtctaagcct tgatttagag caaattctat tatttccatg taaacttcag tttttccact
    14341 tccagttact ccatgaatta agtatggttt tttatcatct acaaacatat tcgactttat
    14401 ctcatcaact gcttcttgtt gctcattgtt taattttata ctttttagta cggatttgta
    14461 aatacttttt ggctctctat aataatcctt aaattctagg gttattagct ttttcttact
    14521 tagagaattt atactttgtt ttgaagcatt taataaatcc aataaatcat ttatctctac
    14581 attttcatta tttttaagaa aacttaatat ctctttttgt ttacttccca catttatttt
    14641 attttgctct atataatcgt caatcttatc actttctaaa ctcaaagata tataacatac
    14701 tttcttttca tttttgtgat ttttatattc ccaacataat tttataattc catttttatt
    14761 cattgtgtac aaagaactat ttaagtttgg tatatatttt aacttatcaa ccttaatttt
    14821 acctttacta tcaatcactt tctctactat ttctctattt ttatcactta aagttgatat
    14881 tttttccttc aattcaatat catttaatcc acttaaactt tcacctaata ggactacttt
    14941 ataattattt aatttgtatc cctttggata tatcaaattt atacattcta tataagtaca
    15001 caaatatcta tttttcatcc aataaaccaa ctctaaatct tcttttctaa atatcggatt
    15061 ttcatctaat atatcaataa tttcttttat ttttattttt tcatctaagc tatctgtaaa
    15121 ttgaaataca aaggcttctg ttggtttatt accttttcca aatggtacta atattctgtg
    15181 cccaattttt attacatcag ataaaaatac aggaatttga tatgtaaata aattatctgt
    15241 atatatagta ttacttctaa ctattacctt tgcatatttt ttcattataa aacctctact
    15301 taaatttaat atattgttca tattttaata tactttacaa gatattaaaa tctcagaatt
    15361 tataagcaat ttcaagttat taatattaac tttattttaa taattaacta ttaattatat
    15421 tttatacttt atgacaaaat aaatgctgaa aactacaatt taactgacat ttgcgagttt
    15481 ttactcgcta aaattaaatt gcagctttca gccactttag ctgtgataaa atacacaaat
    15541 atcatattta aaaaaggtct tatttctcaa gcaacgcttt aactttatct aaaataacat
    15601 tggctacttc ttcttttttc atcttaggat actcagtaat atttccctct acatctatta
    15661 tttttacaat attagtatca gctctaaaac cagcaccttc tttagttaaa tcatttgcca
    15721 caataaaatc taaatttttc ttttttattt ttcctttggc atgttctata aggtcattag
    15781 tttcagctgc aaatccaatt agtatcttat cttcttttat ttttcctatt tcataagcaa
    15841 tatcataatt tctacttagt tctattgata aatcatcatt cttcttttta atttttttgt
    15901 cagaataagt ttttggttta taatctgcaa ctgctgcact ttgaattact attttatttt
    15961 cacttaaatt tgatactact gcttcataca aatcttgtgc tgactctatt tgaacaaatt
    16021 ttttaagatt ttgtggaata gaaagatttg taggacctga tattaatgtt acatcagcac
    16081 ctctagctat agcttctctt gctatagaat atcccatttt accagaagac ctattagtta
    16141 aatatcttac tgggtctata ctctctacag ttggaccagc tgtaactatc atactttgac
    16201 cttttaaatc ttgctcttta gtaagattag tcaaaacttc ctctactatt atatctggat
    16261 tagctagttt acctgttcca atatctccac atgcaagcct tccactttcc ggttcaataa
    16321 atttatatcc aaagctcttt aaagtttgta tatttttttg aacaattgga ttttcataca
    16381 tattagtatt catagctggt gctataagaa cctgtgcttt tgttgccata acagtagttg
    16441 tcaacatatc gtcagctata ccatttgcaa tcttgcctat aacatttgca cttgctggca
    16501 ctattaagaa taaatctgct ttttttgcta atgatatatg ttcaacttcc caagtttttg
    16561 gttcttcaaa catatcttct actacataat tttgactcag cgattgaaat gtaagtggtt
    16621 taacaaattc tgttgctgat tttgtcatta taacatggat atttgcattt agttttttta
    16681 acttacttac aacatcacaa gccttatatg cagctatacc gccacttatg ccaattacaa
    16741 cagttttatc ttttagcatg accttactcc tcttctgaaa tttgttggtg ttgctcagca
    16801 tgatgtctag cttcttctat ctctatttcc tcttctgtca ataatctata tgttattttt
    16861 ccacttgcaa cttctttagt tgctacacat acaggctttt ccttagtttt atttgaaaca
    16921 tatggttctt ctccatcaat taattttctt gctctctttg aaacagtccc cactaaatag
    16981 tatctgttgt ctattttttc tagtacctca ttgatagatg gttttaacat aattataatt
    17041 cctccttaaa tttctctatt ataatatttt tatatctgct aactttattc ttttcagatg
    17101 atattatacc ttctatttct ttagcagatg tttttacatc ttcattaaat ataaaataat
    17161 cataatcctt aatcatttta atttcttcat atgcacagct aaatctcttc tctatttcag
    17221 cttctgtttc tgtacctctt ccaacaattc tattttttaa ttcttcaagt gatggtggta
    17281 gtacaaatat aaatactccc tctgggcaaa cttcttttat ttgttttgct ccttgcattt
    17341 caatctccag taatacatct tgtccttttt ctaaacattc cattattgcc gcttttggag
    17401 ttccataaaa attatcataa atttgagcat actccaaaaa ctcacctttt tctatcatct
    17461 cttcaaactt ttccttactt atgaagaaat aatttactcc atcaacttct ccagttctgg
    17521 gttttcttgt agtagctgat acagaaagtt ttattgtatc attttcttta agtagttctt
    17581 tgcaaatagt accttttcct gcacctgatg gtcctgatac aactagcaat aatccttttt
    17641 tcacaaacat ttaagcattc cccttctaat attgtattct tactctatat tttgtatttg
    17701 ttctcttatt ttttccaatt cgctttttac ttctactact aaattagtta tatttatatc
    17761 agatgacttc gaacctatag tgttagtttc tctattcatc tcttgtatta agaaatctat
    17821 ttttctacct atagagtcgt ctttaaatat agtattttta agttgcccta tatgactttt
    17881 aaatctaact atttcttctg ttatactgct tttatctgca tatattgcaa cttcttgtgc
    17941 taatctattc tcatctatta tacttgggtc atccagtaat tcacttattc tcaaattcaa
    18001 tttttctcta taatcttcta caacactact tgaatatttt tcaatctctt ctatatgatt
    18061 ttttaataaa tcacatctca tggcaatatc ttcagctaat tttttacctt cttcacttct
    18121 catttctctt aatttgatta atgcatcttc aactgcttga ttcaacattg accacaataa
    18181 atcttcatct tcttcctttt cttctatttt cacaatatca ggaaactttg caacattcat
    18241 aacgctaata tcatctataa tatcaaattt attttttatt tcttttagta tgtctatata
    18301 ctgagatgct aatccctcat caaaatttaa gtttacatct tctttgccta ataagtcaaa
    18361 ctttatgtat aaatctactc ttcctctttt tacataattt tttactaaat ttctaacttt
    18421 atcctctaaa aatgaaattt ttcttggaag acgtatgttt atatctgaat acttatgatt
    18481 tatcgtttta cactctacta aaaagtaata attatcatcc ttgtattctc ctcttccaaa
    18541 accagtcata cttatagcca ttaattaaac ctccaaaata ccttcacata tttttactgc
    18601 tggacctgtc atataagaga aatctcctac atctatttta actgttccac cttgagacgt
    18661 tacatttaca ctactttcta ccatattaag taaattgcac actattgctg atgcagtcat
    18721 accagtacca caacctaaag tatatccaca acctctttcc caagtataaa catgtatatt
    18781 atacttatct tctaccttta caaaatttac attcgttttt tcaggaaata ttttattatt
    18841 ttcaatctct tttccatatt tacaaacatc atctacatct aattcatcta ctataactac
    18901 tgtatgagga acccccatca acatagaagt aactttaagc tccctatcta aaacctttat
    18961 actttcttgc acaaaacgtt ctttatttgt aagtacagga acgtccttag ctataaaact
    19021 tccttttccc atattgactc ttatagagtt tatttctcta ttagtaagat ttacttttat
    19081 atcttttata ccatctaatg tatctactgt aaaactttct tttttaacta tacaattatc
    19141 ataaacaaat ttacaaaaac atctaaggcc atttccacac atagctgctc ttgaaccatc
    19201 agaattataa tataccattt ctacatctgc aacttttgaa tctttcacaa ctaacaatcc
    19261 atccgctcct acagaaaatc ttctatggca tacttttttt gctaaagcag tataatcaga
    19321 tggatttatc tggtcgaatc ttccatctat tgctataaaa tcatttccta ttccatgtag
    19381 tttccaaaat ttcataagta tcgctccttc gtaaattaac gcttaaacta ttataacata
    19441 aaaaaattcc cataaactta taatttatgg gaaaagtttt gtaatgacaa ctataatttg
    19501 aggatgtgag ggagagttgc cattacaatt agggtaatta tattatgttt ttaagctagt
    19561 tctttctatg tttatatatt aatatttcta tatgaatttt atgtatgttt tatttaaact
    19621 gtctatgaat tttttaatta aacatctggt aactagctat aatccttcta gtagatatct
    19681 attaacatac acctattaat tctttaagtg tttttaaaac atagtctaaa tcttccttag
    19741 taatatctac atgagttaca aatctatatt caccattttc cattttatta atttttatat
    19801 ttctttcaaa aaattctttt attaaaacat cctcttttat aatatcttca ctcatcttaa
    19861 aaaataccat acttatatct ggattaacat tgtttacttc aatgccatca attttattta
    19921 attcacaagc taaatatttt gcattttcat ggtcttcatt caatcttaaa gtcatttttt
    19981 caatggcaat tataccagct gctgcaacta tacctacttg tctcattccc ccacccataa
    20041 ctttttgctt tcttctagct tttgctataa attctttatt tccagcaagt atagaaccca
    20101 ttggtgcagc taaacctttt gacacacaga acataacact atcacaacac tttgctattt
    20161 ctttagcttc tacacccaaa gttaatgctg cgttaaataa tcttgctcca tctaaatgta
    20221 ctggtaagtt atgtttctca gctatttttt taatttctct taaattatca agactcacaa
    20281 ctgttccacc tgaatatgca ttttctacac atataagccc tgtctgtggt tcatgtatgt
    20341 catctcttct aattgccttt tcaacaagtt caggatttag agctccactt tcgtcttcat
    20401 ctatagttct aagctgaact ccagctatta cagcaggtgc cccaacctca tgagtcacaa
    20461 tgtgataacc tttaccaata attatttctt gccctcttag gcaatgagta aatagagcta
    20521 attgattccc aaaagttcca cttggaagga aaatagcatc ttcttttcca actttagctg
    20581 ctgctaattc ttcaagttta tttacagtag ggtcatctct aaagattgaa tctccaacag
    20641 gagcctttgc catagcttct ctcatttcgt cagtaggcat agtaacagta tcacttctta
    20701 aatcgataaa tctcattttt tcaaccttct ttcatattta tatactatag aaccttaaaa
    20761 ttgatttttt ctgtaaagtt catatacttt catagcttat actctacaca ataattatac
    20821 tatatttact ttatatttaa tctactttaa attattaatt ttaaaaataa agtttcctct
    20881 ctaataaata taaataatta tacaatttaa atattaatct ctattgttta aattccccct
    20941 agtcacaaag cgtatattat gtgtataatt aatttactga ctcattttgg tcaaagaaag
    21001 gggtgctata aatggcatta gatggattag ttatacattc aatagtcgat gaattatcat
    21061 caaaacttac aggtggaaaa atagataaga tacatcaacc tgaagatgat gaggtaattt
    21121 ttaatataag aaataataaa gaaaatttta gattggtttt aagtgcaagt gcctcaaatc
    21181 ctagagttta tcttacaagt aattatcaaa aagaaaaccc tctaaaagcg cctatgtttt
    21241 gtatgttact tagaaaatac atacaaggtg gaaatatagt agaaatttct caaataggtt
    21301 ttgaaagaat aataaaaata agtgttgaat ctttagatga attaaaagaa aagacagtta
    21361 aaaatattat gattgaaatt atgggaagac atagcaacat aataataact catggtgaag
    21421 aaaataaaat tatagattct ataaaaagag tcccttttag cataagtaga gttcgtcaag
    21481 ttttacctgg tcatgattat tcattgccac cagaacaaaa caaactcaac cctcttgatg
    21541 atatatctaa ggatttgttt attaaaaacc tagaggaatt ggaaggacct atctttaagt
    21601 ctatatattc taaatttcta ggtataagcc ctattatagc taaagaaatt tgctacagag
    21661 caggtgtaaa tcaaaatgct atcataaagg atatatctga tgaacaattt gatgctttac
    21721 acaaagtatt ttgtaattta ttcaatgata taaattctaa caaatactct ccttgcatta
    21781 ttatagataa aaaggtggat aaggtagttg atttcagttg tataaacctt acattattta
    21841 gcgatttatc atatataaat aaggatagta tgtctcgtat tctggaagat ttctatagaa
    21901 ctaaggatat taaagataga attaatcaac gttcatctga tttaaagaag agtatatctg
    21961 ttaagcttga tagactttat aataaactta aaaaacaaga agaagaatta tcagaatccg
    22021 aaaatgcaga catttataag ataaaaggag aattgattac ttcatatatt tatatggtag
    22081 aaaaaggtat ggaaagtatt gaagttgcta acttctatga tgaaaattgt aatgatgtaa
    22141 caatagaatt aaataaaaac ttgacaccat ctgaaaatgc tcaaaaatac tttaaaaagt
    22201 ataacaaaat gaaacatgct aaagtcgaga tatctcatca aatttcctta aataaggaag
    22261 aaatagatta cttagaaaac ataattttaa gtattgaaaa ctgtgaaaat ttagctgaat
    22321 tacaagatat aaaagaagaa cttgctaaag ttggatacat caagactcaa aagaaaaaca
    22381 gtaaaaagga tactatccca tctacaaaac ctcatgaatt tgtgtcttct gatggattta
    22441 aaatattggt tggtaaaaac aataagcaaa atgactatct tacactaaga cttgctgata
    22501 atgatgactt atggatgcat acaaaaaata ttcctggttc tcatgtaata ataaagtgtg
    22561 ctggtaagga agtccctgat aatactgtat ttgaaggagc tatgctagca gcattcttta
    22621 gtaagtcaaa actttcttct caggtgcctg tagactatac taagagaaaa aatgtgaaaa
    22681 aacctagtgg ttctaaacca ggtatggtta tttatgaaac taacagtact atttatgtta
    22741 ctcctgaaga agaaacagta gccaagctta aggttaaatc tgaataaatt ctgcactaaa
    22801 tacaaaataa atgttagaca actacacatt atcattctaa ataaaaatag tggccttctt
    22861 ataaagtaca ataataaggc cactttctaa ttagcttact tttaattttc taacaaaata
    22921 cttttctgtt ttaataacta tacttatatt cccaacaaat attttcagtc ttcttatata
    22981 gatgtaatta aaaagttaac actaaaagct attttttaat ttattgattt gttttagtaa
    23041 ttcattatat tctgattcat acaattcttt ttttagatta tctttttcta tagataacat
    23101 agatataaca gttgtaagtc tattttctaa tactagaaga ttttcttttt tgatttggtt
    23161 ttctctacta ggagtttttt tatttctgct aattgtatat tcgtcataat tacaatcaaa
    23221 ctcccttatt ttagcatctt ttatctctat aatatagtta caaatatgtg atacaaatac
    23281 tctatcatga gacactataa gcatagtttt atcagtattt atcagtgcct tttccagtgc
    23341 ttccatagat tttatatcta agtaatttgt tggttcatca aatactaaaa aattattatc
    23401 ttccaatatt attttacata gtgctatttt taccttttct ccaccactaa gtacttttac
    23461 ttttttgtag acatcatcac ctttaaaccc aaataggctt aagtttatcc ttataaaaga
    23521 ttcatcaaat gaactattaa ctttagtatt gtatagaaca ctcttttcct catctaataa
    23581 actttgattt tggtcaaaat aacctacttt taccttgtta tttattttta tattgtcatt
    23641 tttatcagcc aatatttctt ttatcagagt actttttcca cacccattat cacctaacaa
    23701 tgctatcttt ttacctcttt ttatcttaaa ggaaacatta tctaacagga gcttattttc
    23761 taactttaga gtcatatctt ttacctctac tagatttttg ctaattatct ccataccatc
    23821 ttgcatctta atgttcattt ctttagaaac tttaggttta ttctttacct caagtttatc
    23881 aattctgctt tttatagcct tcacatttga gtccaacttt ttcttattag tctgaccacc
    23941 cattttgtgc aacctagctt ctgaattacc cattcttttt ggtgtttttc ttatgccatc
    24001 acttaaagct tttttatata aaagagcttt ttcaagcctt tttttctctt taacatattc
    24061 ttgatactca aaatcagctc tttttacttc ttcatctttt tgcattaaat aatcagtgta
    24121 attgcctttg taagctttta gttttccatc ttctagttct aatatagttg tacataactc
    24181 atccagaaaa cgtctatcat gagatattaa taataatgct ccctcatgcc ttttaaacat
    24241 atcttccaaa accccaatgc tttttttatc taagtttgaa gttggctcat cagctattat
    24301 gatatttttc ttattactca gcgcatctgc tatttttaac ttaacctttt cccctcctga
    24361 taagtgttct tcaaatttat ctggagcatt taaaagactc ttctccttac tatgactaca
    24421 tgtttcaata ttattttcac tctgacttat ataagaatag ctttctgtaa ggtaagtata
    24481 tccttcatca atttctattt ctcccaatat tgcttttaat aatgttgttt ttccttgacc
    24541 atttgaacca actagaccta ttttgtcatt ttctaatatt tcaagtttat ctatatccaa
    24601 aattaattta tctgcataat atttctttaa attctctact tttactaaca acataaaaaa
    24661 tccctcctta acacacttaa atataaggag agattctata aataggcata acaaataaac
    24721 gtatagacta taatctactc tccttaattt aagcattgca aataaagcca ccaaaatagg
    24781 cttttcaaaa attacaatac tttaaattat aaaaaataga ttatattctc attgtcctag
    24841 ttaccttgcc ctttctttca tttattttta atcattatat caacattaat tacaaatgtc
    24901 tatagaaaat taactaattt tagttattca atatacaact tattctttaa atttattctt
    24961 cttcaacttt aaagtcctga ttatttaaaa ttctgtttaa tacaattcca acaattgcag
    25021 ctaaactaag accagttatc tttactgtac ttgttatagg gattccaaca gaaatacctt
    25081 tattagataa atatgttgtt ccaagaccta ttaataatat aactgctatg attaatatat
    25141 ttattttact ttctacacaa gaactgtccc ttatagtttt taatcctaca taagttatca
    25201 tcgaaaatag cattatacta attccaccca taactgaacc tggtatactt tgaagaaatc
    25261 caccaaactt gcctacacat gcaagcaata tagcaaatat tgctgtacgt ctaagtattg
    25321 aagggtcata gtttttagtt atagcaagta ctgctgtatt ttctccataa gttgtattgg
    25381 ctggtcctcc taaacaccct gcaactatag tcgcaaatcc atccccaagt aatgttctat
    25441 ttaatccggg attttctata aagtttttac ctactacagc accattagta gtcatatctc
    25501 ctatatgttc cataaataca gctaatacaa ctggagatat aatcactatt gctcctaaac
    25561 tgaacttagg aactgtaaag ttaggtattg caaataaact tgcttctgta atagtagtta
    25621 tatctactaa tcttaatatc aaacagatta tatacccaga aaaaactgct attaatattc
    25681 ctaattgttt tataaatcct ctaccaaact tattggttaa aattgctatt gctaaagtta
    25741 taaatgctat cacaaaattg gctgaagcca tactaaaagc tgttggcaat aaatttaatc
    25801 ctataactac tatcatagct cctgtaactt gtgcaggaaa atataattta attttattta
    25861 caccaactac ttttactata atcgacatta taatataaat taatcctgct actattatac
    25921 caccttgagc atatgctaaa tctccaccat atgcctcttt agctgctagt ataactggta
    25981 taaacgcaaa acttgaacct aaaaaggcag gtacttttcc ttctgtacaa aaatgaaata
    26041 tcaatgtacc aacaccagca cagaaaattg caactgacgg attaaaacct gtcaaaatgg
    26101 gaactaatac tgtcgctcca aacatggcta atagatgttg taaagacatt atcgtttttt
    26161 tcataaaaac ctccaaaatt attatatata aataaatcct ctgtttaatt aatatctttt
    26221 aattaattat cattccctag attctatttt ttaacctcta tatacttatt atataattta
    26281 tcattatttt acattttacg acatcaaaaa ctcaaataaa ggagaataaa aactacatta
    26341 agactcacat ccataaaatt ataatattta ttttgtgcaa tctatgtaag ctttatcctc
    26401 ctccctgact attcaatgct aagcttttat ataatactta aaaataatta ttctttgatt
    26461 gtaactgaat cttctccatc aatttctaat aaactgacag atataatttc atgtctagaa
    26521 gtaggtacat tttttcctac ataatctgct cttataggca actctctatg ccctctgtcc
    26581 actagcactg ctaattgtat tgatttaggt cttcctatat ctataatagc atctagtgaa
    26641 gctctcacag ttcttccagt gtataaaaca tcatcaacta aaactactgt cttatcattt
    26701 acattaaaat ctaaataagt tcctttaact acaggttcaa catgaatttt ttccaaatca
    26761 tctctataca aagttatatc aatatctcct gtatctactt ttgttccttc tatttgttct
    26821 attttcttag aaattctatt tgcaattggc acacctctag tctttattcc aactaaaact
    26881 agattttcta cacctttatt tctttcaatt atttcatgac ttattctagt aattgctctt
    26941 gctattgcct tttcatccat taattgagct ttttctacca tatcataatt attgtcaaag
    27001 atataatata tctatttgac aaatctactc ctttctttta attttttata aatttatttt
    27061 tatttaaaat ttcaatttaa acaacaaaaa aacttctcat cacaagacaa gaagctctta
    27121 tataaaaaat atacagtgca atttagcaat tgtcttacga tatctctgta tcgtttaaag
    27181 ataatttttt aatctatcaa atcaaattat atatttatat ttcaaatttt tcaagctttt
    27241 ttaaacaaaa tactttaata taagatattt tatttaaatt tcactaaatt tatttactta
    27301 tataaaaaca aaaaatgatt tataagtatt atacaaatag ttattttatc tttttaataa
    27361 cttccttaaa atactcaggt aattctgaat taaattcgat atattcctta gtagtaggat
    27421 gtataaatcc caacttctta gcatgcaaag tttgtccttt taatttaaat ttagtttctt
    27481 ttggaccata tacataatca cctaaaagtg ggtgatttat agacaaagca tgaactctta
    27541 tttgatgagt tctaccagtt tcaagcctag ctctcatatg tgtaaactta tcaaatcttt
    27601 ctacaacttc aaagtgagtg attgcatttt ttccatcttt tactacagcc atttttaatc
    27661 tatccttagg atttctccct ataggtttat caacagttat tttatcttct ttaaccacac
    27721 catagcatat aaattcatac tccctagtta tagtatgttc ctttaactgt tctgctagaa
    27781 aattatgtgc ataattgttc ttagctatca taagaagacc agaagtatct ttgtctattc
    27841 tatgaactat accaggtcta ataacgccat ttattgatga caacttatct ttacaatgat
    27901 ataaaatccc gtttactaac gtattttcat agtttccagg agcaggatgg acaaccatat
    27961 cctgaggttt atttattatt aagacatcat catcttcata tacaatatct attggaatat
    28021 cttgaggtaa aacttctaat actttaggtt ctggtatctc tataacaata ttatcttcct
    28081 ctttaaccag atatctagct ttttctactt tattattaac ctttactttt ccatctttta
    28141 taattttttg tatataactt cttgacatat cacctaattg ttctgctaga taaatatcaa
    28201 gtctaacttc ttcttcctct tcaagtacta aaaactcttt tacttcatcc attatatcac
    28261 ctacttttac tttcaaaaaa taaaacatat atacataaaa acacagttcc tacaactaca
    28321 aatacatcag ctatattgaa tacatattcc catataattc taaagtcgaa gtaatctact
    28381 acaaaaccta atcgtactct atcaattaga tttcccaatg caccagatat aattaatata
    28441 attcccaacc ttccaaatat atgtactttc cttgtattaa gatagtatag tccaaatact
    28501 gttgcaagta atgcaacaat tataaatatc cattgattat tttgtaataa tccaaatgct
    28561 gcacctctat tttcgacata agttaaatga aatacattat ttattattgg tattgttgat
    28621 acatccacca aattattcaa tacccatatt ttagacagtt ggtctaaacc tatgagtaga
    28681 attattatta atatatatag caatgatttt tccccctata aattatttaa aaaccaattt
    28741 tatttgaagc acactattat tattatacaa aaaaaatgct ctaaagagca actttattaa
    28801 aattgtattt tcttaataaa gctagaacaa aatttaaaat agtactactt tttttatatt
    28861 gtagatttct acatatttaa aatcatatca ttatgtataa aaaatttaaa aataccatac
    28921 taatcaatat tttttgtgta ttttatagat taaagattaa tgatgtctgt aatttaaact
    28981 tacaatcacc actaatcttc aaacaaatat ttttactttt gcacttgctt atttttatct
    29041 aaatgttgta taagttcaga tactgttacg aatttatatc ctctctcttt taatttagga
    29101 attactactt ctaaagcttg tatagtttgt gatttatcat ttcttttagt gttataatca
    29161 tgtaaaagta ttatattacc attttggacc tttgtaagga tagtatttat aattgcatct
    29221 actccagggt tagaccaatc tctagggtct aagtttgacc aaagaattat attcatgcct
    29281 ttagaaacta taatatcaca gacactttta ctcatggctc tatatggagg tctaaatatc
    29341 tttggttcta ctcctattac actttttata atattttgcg tatctgttat ttctttttca
    29401 acactactat aactattttt tgcaacattt atatgtgtaa atgtatgatt ccctatttca
    29461 tgcccctcat catattgtct ttttaataat tctttgttat attctacttt ttctccaact
    29521 acaaaaaaag ttgcttttac atcatttttc tttaatatat caagtacttg tggtgtaaaa
    29581 tcctcatctg gaccatcatc aaaagttaat gctaaaattt tttcatcctc atttcctttt
    29641 tttattatta catcttcata atcgtctttt atattgtcat ttaaactata tgcttctttt
    29701 gaactatctt gattatgtgt attatgatta tatgtatata cacctactat agataataaa
    29761 catatacata taccccatat tattttcttc atgtcattac ctcttttcta attcattcta
    29821 gcaatatatt ttataatgtc agttttttaa tctctcaata ttccattttt atttaaatca
    29881 gttaaatttg ttaggtcttc tgaataaaag ttagaatctt ctacatcagg gttttgcatt
    29941 gcatcaccta ataaattatt ttctttcttt gcacaatcat tacataaact tgtatctggc
    30001 aatatatcca atctttctaa atctatttga ttatgacata aatcacaaat cccatatgtt
    30061 ccattctcta ttttagataa tgctaagtct atttgataca atcttccctc ttcatgattt
    30121 attagactgt tttgcatatt ttgcatatat aaatctgttc ccatgtctcc tatatgatta
    30181 tcataactag ataattctcc tgatgaatac ttttcacttg tatgtttagt tgtatctcca
    30241 aataaagtat tatctttcat atcctctact aaattagtta aattttctct ttctttcaat
    30301 aatttatctt tatatttttt agtatccatt tttaacacct ctaattttaa tatttacatc
    30361 ataaaaatag tatgtggaaa agtaaattaa acatacaata aaaataagat ttgattcgaa
    30421 aaatggaatg tctcaaaatg aaatttttag ttcatttaac cctctttttt atatgaaatc
    30481 aaatatattt ttatcctttc agcaataaaa aagagactta tctctatttt gagatagtct
    30541 cttctttgaa cataatttaa atacaatttt ttaattttta tagttattat tttactaact
    30601 tgccaattta tgattatttt gttctttaat atgttttgct tttttaaaga ataaaagacc
    30661 aagaattatt gctacaataa cacctattcc attagatata ttaactggta gtctaaatcc
    30721 ttcttttgct tgcattatat aactaaatgt tactacagtc ataaaaagtg ctggtaatgt
    30781 agttatataa tggtttttat ttgctttgac taaatatgca gaaccagtcc acaacattat
    30841 cattgcaagt gtttgatttg cccaagagaa atatctccaa attatattaa aatctataaa
    30901 tgtaagagca acaccaactg cgaataatgg taaagctatt aaaaatctat ttttgactgc
    30961 atcttgatta taattcattg catctgctat tgtcagccta gcacttctaa atgctgtatc
    31021 tccagaagtt ataggacatg ccacaactcc aagtatagct aaagctcctc caataggccc
    31081 cattaatcca acagatactg tatttactac tgttgctgct ccaccatcat taaatatcac
    31141 attaagttga ggtatgccat ggaaatatga catggctgct gctgcccaaa ctaaagctat
    31201 tataccttct gcaaccattg acccataaaa tactggtctt gcctcactct ctttctcaac
    31261 acatctcgcc ataagtggtg attgagttgc atgaaaacct gatattgctc cacatgctat
    31321 tgttataaat aagtatggga ataaaggtgt tccatttgga ttcatatttt gtaaatttat
    31381 atttggtatg ttatacccct ttattattaa tcctccagct acacctactg ccataattaa
    31441 taatgctgct ccaaataaag gatatatttt accaatcaat ttatctattg gtaaaacagt
    31501 agccataata taataaagta ttatcactcc aacccatatt tgtgcgttta cacctgtcaa
    31561 tgtctttaat aatcctgctg gacctgttac aaatacaact ccaaccaata ctaaaagaat
    31621 aacactaaat attctcattg ctatttttgc accatttcct agataaaggc ctaccaactc
    31681 tgatgcagat gtacctttgt ttttcattga tagatatcct gaagcaaaat cgtgtactcc
    31741 accagcaaag attgttccaa acacaatcca taaaaatgct gatggtccaa ataatgctcc
    31801 ttgtatagct ccaaatatcg gacctaaccc tgctatattt agaaactgaa ttaaaaagat
    31861 tctcttccat ttcattggca cataatctac tccatcccta caagctatag ctggagtttg
    31921 atttttgtca ttggttccaa aaaccttttc tacaaaagta ccatagacaa aataacctac
    31981 tataagtact actattgaac ctaaaaagct taccataaat tcatcccctt agtttttata
    32041 taattgcttt ataaattttt atgagtttaa gaaaactatt tccagttcaa atagtaatac
    32101 ttttttatgc taatataaat attaattaca ttaagtgcat atttaagtac atgaaatgac
    32161 tttatatatg cattaacagc ctaaattctt ttactttgct tctacttaca gttacttcat
    32221 aatcactatt ttttaatttt aatatgtatg tattattaaa ccatggtata atttctttta
    32281 ctttggttaa gtttacgata taagacctat gtgttctaaa aaatgtttta tcatttataa
    32341 gattttcgac ttctgatatg ccttctttta atataaactt ttctttctca gtatatataa
    32401 atgtctgcct ttcattagct tcacagtaat atatatcatc aatatctatt acaactaatt
    32461 tatcaccttt ccaaaggcta attttatgtg ttatttcttc tatctcctga tttactgctt
    32521 ccttcttata tttgtataaa ttactattta cattaaatag ttcaatatca ctcatctcac
    32581 ttttttctaa tttattcagc atagaaataa ttctctcttc agaatatggt ttcaatatat
    32641 aatcaaatac atccaaagaa aaagcatcta ctgcataact ttcatatgct gttataaaaa
    32701 caattttagg tcttgattta aactgattta atgtttttgc aagtagcatt ccatcaagat
    32761 gaggtatatt tatatctaaa aaaattacat ctattttatt ttcctgaata aagtctaaca
    32821 cctctatacc attggtaaat tcacttacta cctcgattcc acttttattt tcaataaaat
    32881 atctcaattc ctttcttgct ggaaattcat cttccactat tatagctctc atacttctac
    32941 tcctttacat aaaatactat caaagtccca ttatctattc ttcttatatt aagccctctt
    33001 ccatacatca gtttaagcct taaatgtaca ttataaagcc caatcttatt ttctggcata
    33061 ttatcttgat atacattatt tataatttcc tcacttatac ctataccatt atcctctatt
    33121 gatattctca cagtattttc taatgaatac ggtaactttt ttatggatat tttcactaca
    33181 ccagctctac cactttctaa aataccatgt attattgcat tttccactaa tggttgtata
    33241 atcaaacttg gaatctttat atttacatct tctatatcat aagatacagt tagtaattct
    33301 ccaaacctag ctttttctat ctctacaaaa gatttaactt gttcaatctc tttatttata
    33361 tcaattaagt tatcactata ttcaagatta tatcttagat aagttgataa atttattatt
    33421 aactctctag ccttatctgg actaaatctt ataaatgaag ctattgtgtt tagggaatta
    33481 aacaaaaaat gtggattaat ttgtctttga agtgctttta tttctgcttt atttctcgct
    33541 tctatatctt ttttatcttt ctcaatcccc tctactatag atataacaaa tcctattcca
    33601 atctgcccaa ctattaaagg taaatatatt ccaccgatta tttgaattgc taaagaatgt
    33661 ggatatgata ttaagtatat aagtaatata gtaaaacttt cagaaatcat gcctaccaat
    33721 attccataca ttactctatg ttgttttggt atcctcttat atagaaatcc tgataataca
    33781 cctgctagta tacttgataa aagacatgga acagatgtta tccccccaat atccataaaa
    33841 tatctatgaa tccctgaaaa aactcctgct gtaataccta ccatcggacc aaataaaatg
    33901 ccacctgata ctatagatat tattctagtg tttactattg accccatata atttatacca
    33961 ctataagttc caaatatggc taaaaaagta aaaactaatg ctatacagac caagtcatta
    34021 aaactatatt cttccttttg aaatatctgc ttaaatattt ttaactttgt tattagaaga
    34081 aacaatacta caataaggct tgtcttttct attaatgcga ttaaaattga tgttttcata
    34141 atctcccttt aaaaaataaa tttttacaca ctctaaattt attatggttg ttataaatta
    34201 catatttgaa gtaatcctat cacaaaactt tccacattta atcttttaat taaataagaa
    34261 atagttgtac ttctattaac aactaatact agctagcata agcttgtaat aacttgtagt
    34321 tattattaac tttacaattc tagtatttaa ttttatactt tagaaatctc ttttcttaga
    34381 aataatactt tcgaatatca tataatacaa tattatgtag attcttactc atacaacata
    34441 tttctttaaa aattttatac tattctttgt tcaaatatct catttgattt aattgtgtt
//
LOCUS       DAJMZY010000034        32705 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.034, whole genome shotgun sequence.
ACCESSION   DAJMZY010000034 DAJMZY010000000
VERSION     DAJMZY010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 32705)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32705)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32705
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.034"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            complement(260..1279)
                     /locus_tag="OE968_001606"
     CDS             complement(260..1279)
                     /locus_tag="OE968_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-binding protein"
                     /protein_id="HCP7218888.1"
                     /translation="MKLIKTIDAVGQVLCHDITQIIPGEFKGRKFKKGHIVKEEDIPV
                     LLSLGKDNLYVWEKSEGMVHENEGALFLKELTAGENLDFSEIKEGKIDFIAACDGLLK
                     IDVDALFDLNCVGEIMMATLHNNFIVNKGLKVAGTRVIPLVIDEKKLEDAKKVVGNRK
                     IVNVVPFKPKKVGIVTTGNEVFYSRIVDKFGPVIEEKVKGFGCEVIGQTICPDDKEII
                     KSAIKEFISQGAELICCTGGMSVDPDDVTPTAIKETGADLVTYGSPILPGAMFLLAYY
                     GEVPIMGIPGCAMYHKTTVFDIVLSRVLIDEKLDKYDIARYGHGGLCMNCDVCTYPAC
                     NFAKI"
     gene            complement(1276..1845)
                     /gene="mocA"
                     /locus_tag="OE968_001607"
     CDS             complement(1276..1845)
                     /gene="mocA"
                     /locus_tag="OE968_001607"
                     /EC_number="2.7.7.76"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor cytidylyltransferase"
                     /protein_id="HCP7218889.1"
                     /translation="MINAVIMASGFARRMGANKLLLNYKGCSIIEHVFREVSKIDFHQ
                     VVVVSQYEEVLLLCNKYGFEYIDNKNANIGQSESIKLGVLNSSKCDGYMFFVGDQPFI
                     DNLYIDKIINTFKLDRDFIVIPRYKDMCGNPVIFPYSKKEELLALKEDEKGKTILKNS
                     SKIKYVEVPKEMLFDIDTKMDYERIGGKL"
     gene            complement(1952..2674)
                     /gene="yqeC"
                     /locus_tag="OE968_001608"
     CDS             complement(1952..2674)
                     /gene="yqeC"
                     /locus_tag="OE968_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative selenium-dependent hydroxylase
                     accessory protein YqeC"
                     /protein_id="HCP7218890.1"
                     /translation="MELSNIIEKNEIITVVGAGGKTSFINYFANFYRDKLKVLLTTTT
                     KIYVPNDYDNIIITIDGTVIPSICHGITVCGSYINNENKLVSIDSSILDEIVDQFDLV
                     LIEGDGSKRKKLKGWNAKEPVVYHKTTKTIGILDITSFGMNINEENIHRVEIFKKIAN
                     LDTSSINSSSTVSIENLKNIVLNPNGLFKNYSGKRVLFINKVENEKYKNLAIKLVENI
                     KEYESEIEIFYGSVKQKFCVRY"
     gene            complement(2857..4134)
                     /locus_tag="OE968_001609"
     CDS             complement(2857..4134)
                     /locus_tag="OE968_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCP7218891.1"
                     /translation="MSNRIKNIHYGTQRQQLKNLTKKEYQALREMCFLAKNLYNVGTY
                     NVRQHYFNQGEHLNYEANYHVCKENENYKLLNSNIAQQILKEVDSSFRSFFGLIKLAK
                     EGKYDFRGIKSPKYLDKEGFFSIIIGQIRIKEDGILNVPMSPAFKKLYGKVSIKVPQN
                     ILEKKIKEIRIIPKHKARFFEIQYCYEIPKSEEVSNQKNALAIDLGLENLCTCVTNLG
                     DSFIIDGKRLKSVNQWANKQNDKIEALKLKKNITAITRKQFKVWNKRNNQVKDYVNKT
                     CFYIIDYCVKNNIGNLIVGYNAKLEKSDNMERKIYRNFIRIPFGEIKGKLEYLCKIKN
                     INFIRQEESYTSKSDFFADDFLPDINVDNVKKYDFKGERITRGQYKSSVGIIINADVN
                     ASLNILKKSQVVNLSNLQNNPQILKQPQRVRIS"
     gene            complement(4273..6579)
                     /locus_tag="OE968_001610"
     CDS             complement(4273..6579)
                     /locus_tag="OE968_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HCP7218892.1"
                     /translation="MINKGIRKIDSTAIVTGKPLYTEDLIMHKDVLTLKLLRSPHAHA
                     KIKNIDTSKAEKIPGVVGIYTYKDVPQVRYCVPGQTEPEASPYDRVLLEDTVRFIGDE
                     VALVAAEDEKTALKALKMIKVDYEVLKPVFDAREAEGNEVVIHPEKDIVEPYPFGLDA
                     KNNIVSKEFFEFGDVEAKLKESDFVVESSYKTQSQSHCMMETHRSYSYKDINDRIVVV
                     SSLQSPHNVKRILRKVLGIPSSKIRVIKPRIGGGFGGKNIAATDIFTAFVTMKTGRPA
                     KFVFTRSETFVGSNSRHEMFFDVKVGADKEGNLKAIELKSLNNTGAYGGNGVSVSSES
                     GHNTLPIYNDIDAVRFNARTVYTNRLPAGALRGYGATQGIFAIDSAIDELAHKIGMDP
                     LEFRIKNIIDRYTNGKAAEDEILSCELRQCIEKGKKLINWDDKYPCKDIGNNKVRAVG
                     MAVANHGSGIPRVDMATVTIRMDEDGTYKLLSGLADLGQGADTIQAQIAAEALNTTVD
                     RISIYTGDSDLCPYDTGAFASCTTTVTGNATIKTANKLKDILLSVAESKLGFKKEDLE
                     LGKDRVFVKNDNSKFVLLEELGRESVGGIGFASDDVPVVLEATESFGMLKKIKPFIAG
                     FAEIELDKNTGEYKVINFACVPDCGTVINPTLARIQVEGGVMMGIGFAMYEDPIFDKD
                     GRLLTDSFLQYKVPTKKEVGNILVDFAENFDPGGPYGAKSLGEIVIHTPAPAIANAIF
                     NATGVRLRELPMTFEKVYMGMKNNNKQL"
     gene            complement(6572..7366)
                     /locus_tag="OE968_001611"
     CDS             complement(6572..7366)
                     /locus_tag="OE968_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD binding domain-containing protein"
                     /protein_id="HCP7218893.1"
                     /translation="MVTIKEYSVPQSLEEAYKILISKKNNVILGGCGFIKLSNKNIGT
                     AIDLKDINLNYIKEDKKNILIGADTSLRSLEIDKTIKNYCSGILSSAVSNIVGVQFRQ
                     GARIGASVFSKYGFSDLIPALLVVGAKVRLYNKGILELSEFLDSELSRDILVEVILPK
                     KDAIAVFDSIRKCTGDFSVLNSAMLKENDTYKIAIGARPQKARLALEASNILNKEKDI
                     DKASIVASKELTYGSNMRASKEYRKDMASALVKRMYNAIEEGMYND"
     gene            complement(7473..8831)
                     /locus_tag="OE968_001612"
     CDS             complement(7473..8831)
                     /locus_tag="OE968_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine/pyrimidine permease"
                     /protein_id="HCP7218894.1"
                     /translation="MKAKSTSKFELDGIPPLKEAIPLGLQHLMAMVIGSCLPAILIAN
                     AAGLNHKMSTLLIQAALVFAGLSTLLQLYPIPLFKGFKLGGGIPVIMGATAMFIGAGV
                     SVASKYGLPVLFGSQIIAGIVIIIIGFGLKKIRFIFTPAVSGTIVACMGLGLFPIAIK
                     NLAGGMGNETFGNPINFIVGISVSLMILGLNKYGKGLFKDASILVSIIFGYILSLILG
                     IVNFSSIQEFTLVALPKPLAFGLDIRLEVVVMFSIIYLVEIADIMGACTLSAVGGLNR
                     QVTDEELSSAVLGNGVLSTIGALFSATPMGMFGQNSAIVSNTKVVSKFVLAIGGIGLF
                     LAGISPLLANLIRTIPPCVVGGATLVIFSTLTTSGLRLVSMDGFNQENSMILGLSMAS
                     GIGFMVAPQVLEKFPKFIETLLADSSVVSGAMVAIIIQALYMVKFPGNKSDKVEDKNK
                     SL"
     gene            complement(10179..11186)
                     /locus_tag="OE968_001613"
     CDS             complement(10179..11186)
                     /locus_tag="OE968_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218895.1"
                     /translation="MVMQVQEKILELLYTINEDVVSIKNDMSEVKQEINVLKEDMSEV
                     KQEMTVMKEDMSEVKQEINVLKGDMSEVKQEMTVMKEDMSEVKQEITVMKEDMSEVKQ
                     EINVLKVDMSEVKQEMTVMKEDMSEVRQEINIMKEDMSEVRQEINTMKEDMSEVRQEM
                     TVMKEDMSEVRQEMTVMKEDTSEVKQEINVMKKDMSEVRQEITVMKEDVSEVKSEVNF
                     MQNKINNINEDMNGIKDEVSIANEKLYGIEIKIDSLECEDKSMKEIQIEQNNILGSLL
                     HNSEINKATHDNIEHNIAYIKGDTNSIKEDIAEIRRDLNLVELATSKNWSDIVKLKSV
                     K"
     gene            complement(11416..12501)
                     /locus_tag="OE968_001614"
     CDS             complement(11416..12501)
                     /locus_tag="OE968_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HCP7218896.1"
                     /translation="MYNFLGKELKSPLIIGSGPLTYSAAGCKILSDAGAGAVVTKTIR
                     KERAINPAPHMVRNTANALLNNEKWTDFEPEQWIDFEIPQMKRDGTVCIASVGHTIEE
                     SSELVEKVANAGADFIELVSYDYRDLIPMLKDAKERVNIPVIVKLPPMIDEIGDFAKK
                     LEEAGADAITACDSVGPAFRIDIETGQPLLGGNGIGYLSGETIKPITLQRIYEIKKQV
                     NIPIIGLGGCVSGDDALEMIMAGADFVGICSVVILKGAQVISKIHDDLKSNLNRLGYN
                     TIENACGIVHNHMGDVNERLSFEFTYDEEKCTKCKMCERVCAYQARKLNDKMELNEEE
                     CRYCGLCISVCKPKALGRKISCSELNV"
     gene            complement(12537..13850)
                     /locus_tag="OE968_001615"
     CDS             complement(12537..13850)
                     /locus_tag="OE968_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HCP7218897.1"
                     /translation="MIAIKSKYLISSADEIYTNSAVVVENDIIKDILPNEEVEIKYKN
                     IEEIIDKSDAIIMPGFVNGHMHQYGVLSRGIPANVHFTDFEGFLNDYWWPFIENRIGL
                     KEVKATTKASAIELIESGVVAFCDTLEAPNTEEGTLIEQGKILEEIGMKAILSLESCE
                     RISFENGLRCLNENSNLIKWSRENSKLINGIMCTHTSFTCSDRFIKKAKEDTKKLNAP
                     MQFHLCESIYEPNYAEKHFGKKAVDYYNDLDILDETVLASQCVKVNDEEIDILKEKGV
                     KVVHMPLSNCEVGGGFSPVPKMIKKGIKVALGTDGYINDFFEVMRGAFLMHKSVEEDA
                     SVMPANLVFRMATEHGAYVLGLQNSGKIAVGNKADIIVMEDEFKTPVTLDNIFDQIVV
                     QGKKEFISNVYIDGRHILKEKQLVDLDKKAIVKEMKEVACEFWKF"
     gene            complement(13851..16142)
                     /locus_tag="OE968_001616"
     CDS             complement(13851..16142)
                     /locus_tag="OE968_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HCP7218898.1"
                     /translation="MVNKEVRKIDSEAIVTGKPIYTEDLIFHKDVLTIKLLRSPHAFA
                     KIKNIDIKNALKVKGVVNIFTYKDVPNYRYSMVGESYPEASPHDQLILEDVVRYVGDE
                     VAIIAAEDERAAIKAMKLIKVEYEVMTPILDARESEGNKILIHEEDDLFCPFDFGLDA
                     TKNIVSREKMGKGDVEKEFKESDVIVEHSYMTQSQAHCMMETHRAYTYIDTNGRLVVT
                     SANQSAYHMRRQVSKALGIPLSKVRVIKPRIGGGFGGKNIAVTEIYASFVTWMTKRPA
                     KLIYTREETFAMTNTRHQMFFDIKIGSDKEGNIKAIDMKALNNTGAYGDNGPSVCSES
                     GHNVLPTYNNVPAIKFDGRTVYTNLVPGGALRGYGATQGTFALDCAIDELAHKLNMDP
                     TEIKLKNIIKKQTEGGIMNFPIRSCALDECIIRGKKLIGWDEKYPVRDIGNNKVRAVG
                     MSVGTHGSGIANIDMAIVNMRMDEDGTYKLFSGSSDLGTGSDTILAQIAAKALNTSID
                     RISVYTGDTDMCPYDTGAYASCTTYVTGNATIKSAESLKQKILKVAQKKLDLPIDDLI
                     LYEDRVCYSEDVEKFVLLSELGKESVGGGNQEVLYSSESYGIQESAKPFLAGFAEIEL
                     DKTTGEFKVINYACSTDCGTVMNPALARIQVEGGVTQGIGLAMYEDPRHGSDGKLQTS
                     NLLQYKVPTKKDIGNIIVDFVDNYEPTGPYGAKSLGEIVIHTPAPAIANAIYNATGVR
                     IRELPITSEKVYMAMKKLNQGGK"
     gene            complement(16132..16926)
                     /locus_tag="OE968_001617"
     CDS             complement(16132..16926)
                     /locus_tag="OE968_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD binding domain-containing protein"
                     /protein_id="HCP7218899.1"
                     /translation="MITIKEYVVPKSLDEAYELLISRKNNIILGGCGFLKLGSKNIGS
                     AIDLKDLALDYINETDDSILIGADTSLRTLELNKVIKNYCNGVISNAVSNIVGVQFRS
                     GARVGASVFAKYGFSDLIPSLLVVDAKVKLYKKGVMNLADFLENELEKDILIEVILPK
                     KDAIGVFDSIRKCTGDFAVLNGAMLKEGSIYKIAIGARPRRAKIAYKASEILSLENDI
                     EKAGEVSSEELSFGSNIRGSKEYRKDMAKALVVRMYNSIGGECDGK"
     gene            complement(16965..17411)
                     /locus_tag="OE968_001618"
     CDS             complement(16965..17411)
                     /locus_tag="OE968_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2Fe-2S iron-sulfur cluster binding
                     domain-containing protein"
                     /protein_id="HCP7218900.1"
                     /translation="MIIKCTINNKEKELSIRPDDFLADTLRENGYVSVKKGCDTGSCG
                     LCTVMVNDKAVLSCNYLTARVEGQHITTLEGVLDEAKKFGDFLADEGADQCGFCAPGF
                     IMMVLAMKRELQNPTEEEVIDYVNGNLCRCTGYKGQLRAIHKYLNT"
     gene            complement(17483..18889)
                     /locus_tag="OE968_001619"
     CDS             complement(17483..18889)
                     /locus_tag="OE968_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HCP7218901.1"
                     /translation="MMDILIKNAIIVTVNKEREVIFDGALVVKDNKIADIGNSKEIES
                     KYTDVKKIIDAKGKVLFPGFINTHNHLFQTLLKGLGDDMVLKDWLETMTFPAANYLEP
                     KDTYDAAMLGCIEGLRSGITTMVDYMYPHSKPGLCDGIIDAYKELGIRGILGRGCMNT
                     GAQFGVHPGIMQDVETVEKDVRRLFEKHHNTENGRIKIGVAPAAIWSNSQEMLEMLWR
                     VVKEYDDALFTVHISETPFDREAAKELHGQYDIDVLEKLGILGPNVLMVHCVYLTEKD
                     MELTKKYDMKVSHNTASNMYLSSGVAPVPEMLKKGITVSLGVDGAASNNSQDMLELMK
                     LTALQHKVNKCDPLAMSAEKVLELATIDGARAIGMEDEIGSLEIGKKADLLIFNPMLS
                     PKAIPMHNPVSTLVYSSSMKNIESVIVDGNIIMEDSKILTANEEKALKDAQDTAERLC
                     VRGTIKNRMEGHKWNSLY"
     gene            complement(18907..20277)
                     /gene="hydA"
                     /locus_tag="OE968_001620"
     CDS             complement(18907..20277)
                     /gene="hydA"
                     /locus_tag="OE968_001620"
                     /EC_number="3.5.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropyrimidinase"
                     /protein_id="HCP7218902.1"
                     /translation="MGTILRGGTIITSDKTYISDLRIEDEEIVEIGNNLEINGDKVID
                     ATGKIVIPGGIDTHTHFDMNAGSITTADNFETGTRAAIAGGTTTILDFAEANEGENLL
                     QGVEAYHKKASGNCYCDYGFHMTITCLNKDTFNHMEKLISDGIVSFKMYMAYDGMKVD
                     DGTIYRVLKKARDLGCIVGFHCENGDLLDVLIEENIQNGNLEPKYHPLTRPNIVEKES
                     VSRLADITKLSNSKSYVVHLSCRESLETVKMAREKNIDMIVETCPQYLLLEDNLYNKD
                     KFEGAKYVMSPPLRKKEDINYLWEGLSSGDIQTVGTDHCSFNFKGQKDLGIDDFSKIP
                     NGAPGVEHRLALLYTYGVLENRISANKFVEVTSTNAAKIFGMYPKKGEIAVGSDADIV
                     ILNINKEETISYKTQKQNVDYTPYEGFKVKCKVEDVFLRGNHVVQSCNVKEHPTGQYI
                     KRKITK"
     gene            complement(20410..21597)
                     /locus_tag="OE968_001621"
     CDS             complement(20410..21597)
                     /locus_tag="OE968_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgeY family selenium metabolism-linked
                     hydrolase"
                     /protein_id="HCP7218903.1"
                     /translation="MLNEQRKQEVTEICQKLIQNPSSSGNEEGVVKAIEESFEKLGFD
                     SWSRDRYGNIVGCIKGNKPGKKILFDGHIDTVPVPDASKWSVPPFEGKIVDGKIYGRG
                     TSDMKGQYTAMMSAVAYFAKDTNRDFAGELYVAGVVHEEIFEGVSAREISKAVQPDYV
                     VIGESSELNLKIGQRGRGEIVVETFGKPAHSANPEKGVNAVYKMANVIQKIQQLVPPT
                     HPVLGDGILVLTDIKSSPYPGASVVPDYCKATFDRRLLVGETREGVLAPIQALLDEMM
                     KEDPELNAKVSYAVEKADCYTGNTIESERFFPGWLYDEEDEFVQAAYKGLKEAGIDSE
                     ITQYSFCTNGSHYAGEAGIKTIGFGPSKENLAHTIDEYIEQEQLFIGTEGYYGILKSV
                     YGK"
     gene            complement(21724..22938)
                     /gene="dpaL"
                     /locus_tag="OE968_001622"
     CDS             complement(21724..22938)
                     /gene="dpaL"
                     /locus_tag="OE968_001622"
                     /EC_number="4.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopropionate ammonia-lyase"
                     /protein_id="HCP7218904.1"
                     /translation="MLKEIKWKVNNLPKGDKENCIKFLNEEEITKVRNFHKSFPQYKE
                     TPLANLEGLAKKLGVAGVYVKDESYRFGLNAFKVLGGSYSMGRYLAQRLDTDISELGY
                     DKLTSKEIKEKLGEITFFTATDGNHGRGVAWTANKLGQKSVVLMPKGSSEFRLNKIKG
                     EGADASITDLNYDDAVRLANDYAEADDHGVMVQDTAWDGYEEIPAWIMQGYGTMAQEA
                     IEQLKEYGVDRPTHVFVQAGVGSLAGAVQGYVASIYDECPITVVVEADEADCYYKSAE
                     AGDGKPRFVGGDMPTIMAGLACGEPNTIGFEVLKNHAAAFVSAPDWVSAKGMRTLGNP
                     LNGDEKVISGESGAVTTGLLVAAMEREDLADLRKDLKLDENSRILLISTEGDTDPDKY
                     RSIVWDGEYPSI"
     gene            complement(23301..23972)
                     /locus_tag="OE968_001623"
     CDS             complement(23301..23972)
                     /locus_tag="OE968_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HCP7218905.1"
                     /translation="MAKILGICGSPRKGATEYAVLEALKEAETIPGIETEYWSVRGKK
                     ISPCVHCDACIRKETMCIIKDDIQELEQKILEADGIIVGSPVYDMNITAQLTAVFNRL
                     RPMYLVHPGKLQNKVGAAITTGGTRYGGQELTKLPIINFFLMHEMLVSGGLGGCYIGG
                     TIWSKDGKAKGAQEDETGMDTVKRLGKGAAEAVMVSKFGLEKWNVVKEELDVKKDEKS
                     PLRDH"
     gene            complement(24055..26271)
                     /locus_tag="OE968_001624"
     CDS             complement(24055..26271)
                     /locus_tag="OE968_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HCP7218906.1"
                     /translation="MEKVIGKSYPLKDAALKVTGQMKYVADMKPQNVLYAKMLLSPVA
                     HAKIKSIDTSEAEKVVGVRAIATYLNTSQRKYNGSLRFYEHKIPENEVIFSDTVRFVG
                     DRVAAVAAETPEIAEKAVKLIKVEYEELPAVFTIQDAIKEDAICIHGDSNIVSQNNIN
                     GGDVEKGFKECDYIFEDEYSTPAIHHSAIETHSVIAHYDYNDKLTVHTPCQNTFGFRI
                     ILSQIFGMSLNKVRVIRPAIGGSFGGKLELTIEPVAAALSKMTRRPVKMVLTRKESMI
                     STRTRHGSFVKLKTGVNKDGEVIAQDIKIYTNTGAYASSALNVIGALSHKVFKVYKIP
                     NIKFTGMPVYTNTPIAGAMRGYGSPQIFMAQQAQFAKIAKEIGMDLVDFQNKNAVEPD
                     DVDIIFHGSLGNPRVLDCIEQGKKMFKWDEKKKLPKEEGKYLRGIGMAIGAHGNGVFG
                     AHRDVVTLTLKLNEDGTLTLLTGAHDMGNGVVTMQTMMVAEVLGITPDKVDTFETDTD
                     ACTFNLGDYASRGVFVEGGGAKKTAEKLKNLILEEAEKLLETSKEDLYLDNGCVISKL
                     DENVKASLSDVAVYSQSKSLRELTVVEDYSSPAGRTSYGVHFAEVLVDKETKDIKVVD
                     FVAVHDVGRVINPLNLEGQLEGGIHMGLGYALSEELAFDEQGRPKATDFKTYKLFRTV
                     DMPKCQVAFVDGYEKAGPFGGKSIGECAVVPVAPAVANAVYNATDVEIHSLPIKLK"
     gene            complement(26274..26744)
                     /locus_tag="OE968_001625"
     CDS             complement(26274..26744)
                     /locus_tag="OE968_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(2Fe-2S)-binding protein"
                     /protein_id="HCP7218907.1"
                     /translation="MEKIKLNINDYMYEIEVEKNETLLHVLREKLNLTGAKQGCNSGS
                     CGACKVLIDGVDMKSCKLLAKNCEGKVIYTIESFANGENLHPIQEAFIEVGAVQCGYC
                     TPGMIITTQALLNRNASPNEDEIREAFKENLCRCTGYVKIIEAVKLSAARLGGR"
     gene            complement(26806..28200)
                     /locus_tag="OE968_001626"
     CDS             complement(26806..28200)
                     /locus_tag="OE968_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HCP7218908.1"
                     /translation="MIDILIKNAIIVTVNKDRDVIFDGAIAIQGDRILDIGNTVDIEP
                     KYLDAKKVIDANGKVIFPGFINTHNHLFQVLLKGLGDDMALHEWLNTMMFPSAKFLTE
                     QDTYDAAMLGCMEGLKSGITTMVDYMHTHNRPGLTDGIVKAYKDLGIRGVVGRGCIDL
                     GIHKELIEDVETVEKDLRRVFEKYHNSENGRIKICVAPSSMWAISEEMGKMLWNIVKE
                     YDSYFTVHISETEFARTATKDIHGEIDIKLLEKWGIVGPEVVAVHCVCITDEDMEMLK
                     KYDIKVSHNVASNMYLASGVAPVPEMLKKGINVSLGLDGAASNNAQDMVELMKLTALQ
                     HKVNNCDPLAISAEKVLEMATIEGARTLRMEDEIGSLEIGKKADLVIFNSMLSPKSIP
                     LHNPVSTLVYSASMHNVESVLVDGNVILENGKVTTIESEEQVLLNAQHAAEELCKRAN
                     VTNRMEGHKWNSLY"
     gene            complement(28273..29634)
                     /locus_tag="OE968_001627"
     CDS             complement(28273..29634)
                     /locus_tag="OE968_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine/pyrimidine permease"
                     /protein_id="HCP7218909.1"
                     /translation="MKTRNTSKYDVDGIPPLKESIPLALQHLLAMIVGNMVPAILIAN
                     VVGLNQGQATMLIQGSMLAAGLATFLQLYPIPLFKGFKLGSRLPVMMGMSYVFLGACL
                     SVAAKDGLAALFGAQIAAGVIVFFVGFGVKKIRHIFTPIVSGTIIACMGLGLFATAIK
                     NLAGGEGTQTFGSPINFTVGVIVAFVIIMINKYGKGLVKNSSILIGILVGYAISLVLG
                     LVDFSAVQGAAIVSLPTPAAFGLEFRPELIVMFTIIYIIGIADMMGACTIATVGAMDR
                     EVTDEELASVVLGNSITSIISSLFAALPTGVFSQNTAIVSMNKVTSRFVIALGALVLL
                     LAGISPALGAIMTTIPSCVVGGATLVVFSSIAMSGFSIMSMDGFTEENNLIAGVSIAT
                     SMGLTTAPQVLDQFPETIGTVLGGSSIVSGAIIAILLQTLFKLKSRKSAENVTSNLEE
                     NIG"
     gene            complement(29931..31253)
                     /locus_tag="OE968_001628"
     CDS             complement(29931..31253)
                     /locus_tag="OE968_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HCP7218910.1"
                     /translation="MFDIDGRPPILKCLPLSMQHILAMIVGTVTVPIVVGGAVGVSPT
                     QITLLVQYALIIAGISTLIQLYPIGNIGSRLPIIFGVGFTYVPTLVAVGGNYGLASIL
                     GAQLIGGVATVLIGIFIKKIRKFFPNIVAGTVVFTIGLSLYPIAINYMAGGVNSPTYA
                     SMQNWAVAAITLVVVIGLSQFAKGYAKLAAIFLGIIVGYCVSLVLGIINFDPIREATW
                     FAIPKPLEFGMEFDMPVIISVVIVSIINAVQAIGDLSATTMGGMDRNITDKELSSGVI
                     GSGICTMIGALFGGLPPSSYSQNVGMVAMNKVISRFVLGIAGIFMLLSGFVPKFGALM
                     TTIPYSVLGGATISIFSIITMTGIKLIITEELSSRNITIVGLAIALGMGITSVPAAQE
                     AFPSFVKLVFGESPIVIATLVAFVLNLIIPNKSLEDEAKERAVMEETN"
     gene            complement(31609..32649)
                     /locus_tag="OE968_001629"
     CDS             complement(31609..32649)
                     /locus_tag="OE968_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HCP7218911.1"
                     /translation="MDKHSDSVMYGGMEVYNIWGTTTVDSIIGESDVMRALKNRICKI
                     GNSDSTVAITGESGTGKELIARAIHLAGNRGNKTFVAINCAAIPEPLLESELFGYTKG
                     AFSGADSKGKIGKFELANGGVVFLDEIGDMPIQLQSKLLRVLQEKKFTRIGSNELIDI
                     DVRIISATNRDLFELVKENKFREDLYYRLNVIPLEVPPLRERGDDIQILINNFIDKYS
                     RKMKKNVYHIEPDVEQMLLKYPWPGNIRELENTIELALNLLEEDGIIHKGIINRKILE
                     YFKLNNINIKLLEESDYEISMEQDILTLEEFERAYIKKVLKFYGNDTKSKKLAAKKLG
                     ISLATLYRKIDV"
BASE COUNT         9904 a         6446 c         3547 g        12808 t
ORIGIN      
        1 gtaaatagta tattttttat actaaatttg tgaaatattt attaaaataa tactaaaaat
       61 tgtaaattta taaaaattaa caatctctta tattatactt ataaagaaat caaattgcaa
      121 ctttattcat tcttttacac attgaaaata agttattata atttctaaat aaatatgctt
      181 ttcttaaaac atcattctag ctgttttgtt tcatatttaa aaagagtact taatttgtaa
      241 atactctttt ttaataactt tatattttag caaaattaca tgcaggataa gtacatacat
      301 cacagttcat acaaaggcca ccatgaccat atctagctat atcatactta tcaagctttt
      361 catcaattaa aaccctagat aaaactatat caaatactgt agttttgtga tacattgcgc
      421 atcctggtat acccataatt ggaacttctc cataataagc aagtaaaaac atagctcctg
      481 gtaatattgg tgaaccatat gtcactaaat cagctccagt ttcttttata gctgttggtg
      541 taacatcatc tgggtctaca ctcatcccac cagtacaaca gataagttct gctccttgac
      601 ttataaattc ttttattgca ctctttataa tttctttatc atctgggcat atagtctgtc
      661 ctataacttc acaaccaaag ccttttactt tttcttctat tacgggtcca aatttatcaa
      721 caattctgct ataaaacact tcatttcctg tagtaacaat tcctactttc ttaggtttaa
      781 aaggtactac atttactatt tttctattac caactacttt ttttgcatct tctaattttt
      841 tctcatctat aactaaaggt atcactcttg ttccagctac ttttaaacct ttatttacta
      901 taaaattatt atgaagagta gccatcatta tttctccaac acaattcaaa tcaaaaagtg
      961 catcaacatc tatctttaat agaccatcac atgctgctat aaaatctatt ttcccttctt
     1021 ttatttcact aaaatctaaa ttttctccag cagttagttc ttttaaaaac aatgcgcctt
     1081 cattttcatg aaccattcct tctgactttt cccatacata caaattatct ttaccaagag
     1141 ataataacac tggaatatct tcttctttta ctatgtggcc ctttttaaat tttcttcctt
     1201 taaattctcc aggtattatt tgagttatgt cgtgacataa aacttgtcca acagcatcta
     1261 tagtttttat tagcttcata atttaccccc aattctctca taatccattt ttgtatcgat
     1321 atcaaataac atttctttag gaacttctac atactttatt tttgatgaat tttttaaaat
     1381 ggttttacct ttttcatctt ctttaagtgc caacaattct tctttcttac tatatgggaa
     1441 tatgactgga tttccacaca tatctttgta tcttggaatt actataaaat ctctatctaa
     1501 tttaaaagta tttataattt tatctatata taagttatca ataaatggct ggtctcctac
     1561 aaagaacata taaccatcac attttgagct atttaaaact cctaatttta tagattcact
     1621 ttgacctata tttgcatttt tattatctat atattcaaaa ccatatttat tacacaataa
     1681 caaaacctct tcatattgac ttactactac aacttgatga aaatcaatct tgctaacttc
     1741 tctaaataca tgttctatta tagaacagcc tttataattt aataaaagtt tatttgctcc
     1801 cattcttctg gcaaagcctg atgccattat cactgcattt atcatatata tcatccttgg
     1861 tatttataat atattgatag ttctatgatt tttataatat ctctattgat attatctata
     1921 tatataatat catataaact attttaatac ttcaatatct tacacaaaat ttttgtttta
     1981 cacttccata aaatatctct atttcacttt catattcttt aatattttct actaatttta
     2041 tagctaaatt tttatatttt tcattttcaa ctttattaat aaataatact ctttttccag
     2101 aataattttt aaataatcca tttggattta atactatatt ttttaagttt tcaatactta
     2161 ctgtagaact actattaata ctacttgtat ctaaatttgc tattttttta aatatttcta
     2221 ctctatgtat attctcttca ttaatattca ttccaaatga tgttatatct aatatcccta
     2281 tggtttttgt agttttatga tatactactg gttctttagc attccaacct ttaagttttt
     2341 ttctctttga gccatctccc tctattaaaa ctaaatcaaa ttggtctaca atttcatcca
     2401 aaatagagga atcaatactt actaatttat tttcattatt tatataactg ccacagactg
     2461 ttattccatg acaaatagat ggaataacag ttccatctat tgtaataatt atattgtcat
     2521 aatcgtttgg tacatatatt ttagttgttg ttgtaaggag aactttcaat ttatctctat
     2581 aaaaatttgc aaaatagttt ataaacgaag tttttcctcc tgctccaact acagttatta
     2641 tttcattctt ttctattata tttgatagtt ccacactttc acctcttata accagttttc
     2701 taatctctta attattatag ttagaccttt ttagtaaaag tgatttttga aattccataa
     2761 actcgaaagt aaatagattc tgttgtaaac aacaaggcgg atccaattcg ccgctaagct
     2821 gtaagcttac gctatcagtt tatcttttaa atataattaa gatattctta ctctctgtgg
     2881 ttgctttaat atttgaggat tattctgtaa attagataaa ttaactactt gtgatttttt
     2941 tagtatatta agactcgcat ttacatctgc atttataatg attccaacac tggatttgta
     3001 ctgtccacgc gttattcttt cccctttaaa gtcatatttt ttaacattgt ccacattgat
     3061 atcaggtaga aaatcatcag caaaaaaatc tgatttacta gtatagcttt cttcttgcct
     3121 aataaaattg atatttttta ttttacacag atattctaat tttcctttta tctctccaaa
     3181 tgggattctt ataaaatttc tatatatttt tctctccata ttatcacttt tttctaactt
     3241 agcattatat cctacaatta aatttccaat attatttttt acacaataat caattatata
     3301 aaaacaggtt ttatttacat agtctttaac ttgattattt ctcttattcc aaactttaaa
     3361 ttgttttctt gttattgcag ttatattctt ttttaatttt aaggcttcta ttttatcatt
     3421 ctgtttgttt gcccactgat tcacagattt tagccttttt ccatctatga taaaactatc
     3481 acctaaattg gtaacacatg tacataaatt ttctaaaccc aagtctatag ctagtgcatt
     3541 tttttgattt gaaacttcct ctgattttgg tatttcataa caatactgaa tttcaaagaa
     3601 cctagcttta tgtttaggta ttattcttat ttctttaatt tttttctcta gtatattttg
     3661 tggaactttt atacttactt tcccatatag ttttttaaat gctggagaca taggtacatt
     3721 taaaatccca tcttctttga ttcttatttg acctattatt atgctaaaaa atccttcttt
     3781 atctaaatat ttaggtgatt ttatccctct aaagtcatat tttccttctt tggctaattt
     3841 aattaatcca aaaaatgacc taaacgaact gtctacttct tttaatattt gttgcgctat
     3901 attactattg agaagcttat agttctcatt ttctttgcat acatgataat tagcttcata
     3961 gttaagatgt tctccttgat tgaaataatg ctgtcttaca ttatatgtac caacattata
     4021 taagttctta gctaagaagc acatctctcg tagagcttga tattcttttt tagttaagtt
     4081 ttttaattgt tgtctctgag ttccatagtg tatatttttt attctgtttg acatgaactc
     4141 acctccttta gaatatactc tactagacat tatatacggt atttttacaa aacaccatat
     4201 ataatgtcca tttaattact ttattttaca aaataattta aatttacttg cttttataca
     4261 cattattatt tattataatt gtttattatt atttttcata cccatataaa ctttttcaaa
     4321 agtcatagga agctctctta aacgaactcc tgtagcatta aatattgcat ttgctatagc
     4381 tggtgctggt gtatgtataa ctatttctcc taatgattta gcaccataag gacctcctgg
     4441 gtcgaaattc tcagcaaaat ctaccaatat atttccaact tctttttttg taggaacttt
     4501 atactgtagg aaactatctg ttaataatct accatcttta tcaaatatag ggtcttcata
     4561 cattgcaaac cctataccca tcatcacacc accttctact tgtattctag ctaaagttgg
     4621 atttataact gttccacaat caggtacaca tgcaaaattt atgactttat attcgcctgt
     4681 atttttatct aattctatct ctgcaaatcc tgctataaat ggttttattt ttttcaacat
     4741 gccaaaagat tctgttgctt ccaaaactac tggtacatca tcactagcaa atcctattcc
     4801 tccaacagat tctctaccca attcctctaa tagaacaaac ttgctattat cgtttttaac
     4861 aaaaaccctg tcttttccca actctaaatc ttctttttta aatcctagct ttgactctgc
     4921 aactgaaagt aatatatctt ttaatttatt tgctgtcttt attgttgcat ttcctgtaac
     4981 cgttgtcgta caagaagcaa atgctcctgt atcataggga cataagtctg aatcacctgt
     5041 ataaatagaa attctatcta cagtagtatt taaagcttcc gcagcaattt gagcttgaat
     5101 tgtatcagcc ccttgaccta agtcagcaag accagataat agtttatatg tgccatcttc
     5161 atccattctt atagtgactg ttgccatatc tacacgcggt ataccagaac catgatttgc
     5221 tactgccata cctactgctc ttactttgtt gtttcctata tctttacatg gatatttatc
     5281 atcccaatta attaatttct tgcccttttc tatacattgt ctcagctcac aacttaatat
     5341 ttcgtcttca gctgcttttc cattggtata cctatctatt atatttttaa ttctaaattc
     5401 aagtggatcc attccaatct tatgtgccaa ttcatcaata gcactatcta ttgcaaatat
     5461 tccctgtgta gcaccatacc ctctaagtgc tcctgctggt aacctattag tatatactgt
     5521 tctagcatta aatctaacag catcaatatc attatatatt ggtaaggtat tgtgtccaga
     5581 ttcggaagaa acagagacac cattcccacc ataagcacct gtattgttta atgactttag
     5641 ctctattgct tttaaatttc cttctttatc tgcaccaact ttaacatcaa aaaacatttc
     5701 atgtctacta ttagaaccta caaaagtttc acttcttgta aatacaaatt ttgctggtct
     5761 accagttttc atagtaacaa atgcagtaaa tatatctgtt gctgctatat tctttcctcc
     5821 aaatccacca cctattctag gtttaattac tcttattttt gaagatggta tacccaatac
     5881 ttttctaagt attctcttta cattgtgtgg tgattgtaat gatgaaacta caacaattct
     5941 atcatttata tctttatatg aatatgacct atgagtttcc atcatgcaat gcgattgact
     6001 ttgggttttg tatgaagatt caaccacaaa atcactttct ttaagcttag cttcaacatc
     6061 tccaaattca aaaaattctt ttgatactat attatttttt gcatccaatc caaaaggata
     6121 tggctctact atgtcttttt ctggatgtat aacaacttca tttccttctg cttctcttgc
     6181 atcaaacaca ggctttaaaa cctcataatc tacctttatc atttttaagg ctttaagtgc
     6241 cgttttctca tcttcagcag ccactaaagc tacttcatct ccaataaatc taactgtatc
     6301 ttcaagtaaa actctatcat aaggtgatgc ttctggttct gtttgacctg gcacacaata
     6361 tctgacctgt ggtacatctt tatacgtata aatacccaca acccctggaa ttttttcggc
     6421 ttttgatgta tctatattct ttatcttagc atgagcatgt ggacttctaa gtagttttaa
     6481 tgtcaaaaca tctttatgca taatgaggtc ttcagtatat agaggttttc ctgtgacaat
     6541 tgctgtacta tctatctttc ttatcccctt attaatcatt atacattccc tcctcaatag
     6601 cattatacat ccttttaact aatgcacttg ccatatcctt tctgtactct ttactagctc
     6661 tcatattact tccataagta agttccttac tagcaacaat agatgcctta tctatatctt
     6721 tttctttatt taatatatta ctcgcttcaa gtgctaatct agctttttga ggtcttgccc
     6781 caattgctat tttgtaagta tcattttctt ttagcattgc tgaatttaat acagaaaaat
     6841 ctcctgtgca ttttcttatt gagtcaaaaa cagctattgc atcttttttt ggtagtatta
     6901 cttcgaccaa tatatcccta cttaattcac tatccaaaaa ctcacttaac tctagtattc
     6961 ctttattgta taatctcacc ttcgctccaa caaccaaaag cgctggtatt aagtcagaaa
     7021 agccatactt tgaaaataca cttgcaccaa ttctagcccc ttgtctaaat tgaacaccaa
     7081 ctatattaga aacagcgctt gaaagtattc cactacagta attttttata gttttatcaa
     7141 tttctaaact tctaagtgaa gtatctgcac ctatcaaaat atttttttta tcctctttta
     7201 tataatttag atttatatct tttaaatcta tcgctgttcc tatattttta ttacttaatt
     7261 ttataaatcc acatccacct aaaataacat tatttttttt agaaattaaa attttatatg
     7321 cttcttctaa actctgtgga actgaatatt cctttatagt aaccatctta tccccccatc
     7381 attaacttat taaaacacaa aagtttttaa taaatctttt atttatattt ataattgtag
     7441 tatatttaat tcacatatat taaaccttta cattataaac ttttattttt atcctcaacc
     7501 ttatcacttt tatttccagg aaattttacc atatataaag cttgaattat tatggctacc
     7561 attgctcctg aaactacact tgaatctgca agtaatgtct ctataaattt tggaaatttt
     7621 tcaagaactt gaggagctac catgaatcca ataccagaag ccatagaaag acctaatatc
     7681 atgctatttt cttgattaaa tccatccata ctaacaagtc ttaaaccaga tgttgtaaga
     7741 gttgaaaata taacgagtgt tgctcctcca accacacagg gaggaattgt tcttattaaa
     7801 ttagctaata aaggcgatat tcctgccaaa aataatccaa ttcctccaat agctagtaca
     7861 aatttactta caacctttgt attggaaacg attgcagaat tttgtccaaa catccccatt
     7921 ggagttgcag aaaataatgc acctattgta gagagtactc catttcctaa aacagcagaa
     7981 gaaagttctt catctgttac ttgtctatta agccctccta ccgcagaaag tgtacaagca
     8041 cccattatat cagctatctc aactaaatat attattgaaa acattacaac aacttcaagt
     8101 cttatatcta gcccaaaagc aagtggtttt ggaagtgcaa ccaaagtaaa ctcctgaatt
     8161 gaagaaaaat ttactatacc caaaattaat gataaaatgt atccaaaaat tatgctaact
     8221 aatattgatg catctttaaa taatcctttt ccatacttat ttaatcctaa tatcataaga
     8281 gatacagata ttccaactat aaaattaatt ggattcccaa aagtctcatt gcccataccc
     8341 ccagctaagt tttttatagc tattggaaaa agtccaagac ccatacatgc aactattgtt
     8401 cctgatacag ctggagtaaa tataaatcgt atttttttaa gaccaaaacc aattataatt
     8461 attactatac cagctattat ttgagagcca aataatactg gtagtccata cttacttgca
     8521 acagataccc cagctcctat aaacatagct gtagctccca ttataactgg tattcctcct
     8581 cctaatttaa aacctttaaa caaaggtatt ggatataatt gtaataaagt tgataatcct
     8641 gcaaaaacta atgcggcttg aatcaataat gttgacatct tatgattaag tccagctgca
     8701 tttgcaatca atatcgctgg taaacaacta cctattacca ttgccattaa gtgttgtaac
     8761 cctaaaggta ttgcttcctt tagtggtggt attccgtcta attcaaattt tgatgtactt
     8821 tttgctttca taataaaaac tcccgttaca taaaacttat tgaattatat aaatacttaa
     8881 aaatctaata tattaaatta atgatgttca taaatatcaa ctatactcca acatatattt
     8941 aagtttttag tcttaaaaaa cagatgcaat aaatttaatt attaacaaat aaacgtattc
     9001 tttaattttg tatacattat ataccatgct ttacaaatat aagagtatta tagctatgaa
     9061 tttttaattt tttatagtaa atttaattca atttaaatct ttcaatctta atcattataa
     9121 gttataagtt ttcataagta tttacatgtt tcaagtttta aacatttacc tataaacgct
     9181 actttataga tgtcacttca aatccagtga cctcatactt tcatatgagc gtagactatt
     9241 tcttcatctt cagcattacc tgctaagagc aacccgtttc cactatcaat cgcttatagt
     9301 gtactctctc tcgagatagt cgtttgacct tcctatttct aggcttggcg accaaatgtc
     9361 catttttaag tacttaggct ctcaccatat accatcctca ctattgtttc tggttttcac
     9421 cacattcata aaagtttctt tctatctttt attgtagttg caaggcttta ggatttactg
     9481 gttttaaagt tgtgtcctac atagatttct ctatgtacgg ggccaaaagt acaatttatt
     9541 taacatactt tgctttaccc cctgtaaata atattattta ctctttcact gtttttgtta
     9601 ttaaattaat taaatatcaa ttaatctaag cataaaataa ttatttaatt taaactcaaa
     9661 atatttatga atattttata atataattct cataagacag aaaaacttaa taagctatgt
     9721 atctcagttg taccaatgta ctctccttta ctatatttgt atctgcaaca taaaatatac
     9781 aagtttctat ctatttatag atatatatat ctataagcaa aatagtaata ttatttttaa
     9841 tagtaaaaat tttattcata ttactattta taatttttat agagcaattt tagtgccaat
     9901 atttgcatac atttgtatag tataaaattt ttatgttctc attgataaaa ttttacttat
     9961 ttcaagcgtt ctattagatt ttatcatcta aattttaggt tttattttta taaattaatt
    10021 gtatttacat aaaaaaaaag acctaaaaac aaatttttaa cggtcttttc tcaatttttt
    10081 attttcattt ctaaaattta taataaatag taagaacact ataaattctt ttatataaaa
    10141 ttcttagttt gtggatgata aattagtgaa ttaaaatact actttactga ttttagtttg
    10201 acaatatcac tccaattttt actagtggct aactctacta aatttaagtc tcttcttatt
    10261 tcagctatat cctcttttat agaattagtg tcacctttta tatatgctat gttatgttct
    10321 atattatcat gagtagcttt atttatttca gaattatgta ataaacttcc taaaatatta
    10381 ttctgttcta tctgtatctc tttcattgat ttatcttcac attctagact atcaatctta
    10441 atttcaattc catataattt ttcatttgct atggatacct cgtccttaat tccattcata
    10501 tcttcattaa tgttatttat tttattttgc ataaagttta cttctgattt aacttcggaa
    10561 acatcttctt tcattacagt tatttcttgt ctcacttctg acatgtcttt tttcattaca
    10621 tttatctctt gttttacctc tgatgtatct tctttcatta cagtcatttc ttgtcttact
    10681 tcggacatat cttctttcat tacagtcatt tcttgtctta cttccgacat atcctctttc
    10741 attgtattta tctcttgtct tacctcagac atatcctctt tcattatatt tatctcttgt
    10801 cttacctcgg acatatcttc tttcattaca gtcatttcct gttttacttc ggacatatct
    10861 acttttaata catttatttc ctgttttact tcggacatat cttctttcat tacagttatt
    10921 tcttgtttta cttccgacat atcttctttc attacagtca tttcttgttt tacttccgac
    10981 atatctcctt ttaatacatt tatttcctgt tttacttccg acatatcttc tttcattaca
    11041 gtcatttctt gttttacttc cgacatatct tcttttaaca catttatttc ttgttttact
    11101 tccgacatat cattttttat gctaactaca tcttcattta tagtatataa taactctaaa
    11161 atcttctctt gcacttgcat caccatccct attaattatt ataacatttt acacaaatgc
    11221 tatacaatgt taacatatat atcagaatta ttaaaatttt aattaaacaa aattgattca
    11281 ctttattact tcaaaactaa ttaatatcta aaataactac aaataaacaa aaataaggtc
    11341 aacaacaaaa aaggcttatc tctttgagat agcctttctt atttttattt aaaactttgt
    11401 tttttataaa ataatctata cattcagctc tgaacatgaa atttttcttc caagtgcttt
    11461 tggtttacaa actgatatac aaagtccaca atatctacac tcttcttcat tcaattccat
    11521 cttatcattc aattttctcg cttgatatgc acaaactctc tcgcacatct tacatttagt
    11581 acatttttct tcatcataag taaactcaaa gctaagtctt tcattaacat ctcccatatg
    11641 attatgtact ataccacaag cattttctat agtattatat cctaatctat taagattaga
    11701 ttttaaatca tcatgtattt tagatattac ttgtgcgcct tttaaaatta ctactgaaca
    11761 tataccaaca aagtcagcac ctgccataat catttctaag gcatcatctc cacttacaca
    11821 tccacctaag ccaattattg gtatattaac ttgttttttt atttcatata ttctctgtaa
    11881 agttattggc ttgatagttt ctccacttaa atatcctatt ccatttccac ctaataaagg
    11941 ttgccctgtt tctatgtcta ttctaaatgc tggtcctaca gaatcacaag cagttattgc
    12001 atctgctcct gcttcttcta attttttagc aaaatcgcct atctcatcta tcataggagg
    12061 aagtttaact attacaggta tatttactct ttcctttgca tctttaagca ttggtatcaa
    12121 atctctatag tcataagata ctaattcaat aaagtcagct cctgcatttg caactttctc
    12181 tactaattcg ctactttctt caattgtatg acctactgaa gctatacaga cagtcccatc
    12241 tcttttcatt tgtggtattt caaaatctat ccattgctct ggctcaaaat ctgtccattt
    12301 ttcattattt aaaagagcat tagctgtatt tctaaccata tgtggtgctg gatttatagc
    12361 tctttctttt cttatagtct tagtcacaac tgcccctgct cctgcatcac ttaatatctt
    12421 gcatccagct gcactatatg ttaatggtcc tgaacctatt ataagtggtg attttaattc
    12481 tttacctaaa aaattataca ttatctgctt ccccttttca tatatattta cattcgttaa
    12541 aatttccaaa attcacaagc aacttctttc atttctttaa caatagcttt tttatctaaa
    12601 tcaactaact gtttttcttt taaaatatgt ctaccatcta tgtatacatt tgatataaat
    12661 tcttttttac cctgaactac tatctggtca aatatattat caagagtcac aggagtttta
    12721 aattcatctt ccataactat tatatcagcc ttattaccaa ctgctatttt accagaattt
    12781 tgaagtccta atacataagc accatgctct gttgccattc taaatactaa atttgctggc
    12841 attactgatg catcttcttc aactgattta tgcattaaaa atgcacctct cataacttca
    12901 aaaaaatcat ttatatatcc gtcagtaccc agtgccactt ttataccttt tttaatcatt
    12961 tttggtactg gagaaaaacc tccacctact tcacagttgc taagaggcat atgaaccact
    13021 tttacacctt tttcttttaa tatatctatt tcttcatcat ttacttttac acactgagat
    13081 gctaatacag tttcatccaa tatatctaaa tcattatagt agtcaactgc ttttttgcca
    13141 aaatgttttt cagcatagtt tggctcatat atactctcac ataaatgaaa ttgcattggt
    13201 gcatttaatt tttttgtatc ttctttagct ttcttaataa atctatcaga acatgtgaag
    13261 cttgtatgtg tacacattat tccatttatt aatttactat tttctctact ccactttatt
    13321 aaattagaat tttcatttaa acatctaagt ccattttcaa agcttattct ttcacaactt
    13381 tctaaggata aaatcgcttt catgcctatt tcttctagta tttttccttg ctcaattaaa
    13441 gttccttctt ctgtatttgg agcttctagg gtatcacaaa aagctaccac accagattct
    13501 ataagttcta ttgctgatgc tttagttgtt gccttcactt ctttcaatcc aattctattt
    13561 tctataaatg gccaccaata gtcatttaag aaaccttcaa agtcggtaaa atgtacattt
    13621 gccggtattc ccctagaaag aactccatat tgatgcatat gaccattgac gaatcctggc
    13681 attattatag catctgattt atctattatt tcttcaatat ttttatattt tatttcaact
    13741 tcttcatttg gcaatatatc ttttataatg tcattttcta ctacaacagc agaatttgta
    13801 tatatttcat cagcagaaga tattaagtat ttacttttaa tagcaatcat ttatttacct
    13861 ccctgattta attttttcat ggccatataa actttctcag aagttatagg aagttctctt
    13921 atacgaactc ctgtggcatt gtatattgca tttgctattg ctggtgcagg tgtatgaata
    13981 actatctctc ctaaagattt agctccatat ggacctgttg gctcataatt atctacaaaa
    14041 tcaacaatta tgtttcctat atcttttttt gttggaactt tgtattgtaa tagattagaa
    14101 gtttgaagct ttccatcaga accatgtcta gggtcttcat acattgcaag ccctatacct
    14161 tgagttacac caccttcaac ttgtattcta gcaagtgcag gattcataac tgtaccacaa
    14221 tctgtagaac aagcataatt tattacttta aactcccctg ttgttttatc taactctatt
    14281 tcagcaaatc ctgctaagaa tggtttagca ctctcttgta taccataaga ttcagatgaa
    14341 tataaaactt cttgatttcc accaccaaca gattcttttc ctaattcact taacaaaaca
    14401 aacttctcta catcttcact ataacaaact ctgtcttcat atagtattaa atcatctatt
    14461 ggtaaatcga gtttcttctg tgctactttt aatatctttt gttttaaact ttcagcagat
    14521 tttattgtag catttccagt tacataagta gtacaagaag cgtatgcacc agtatcatat
    14581 ggacacatat ctgtatctcc tgtataaacg gaaattctat caatagatgt attcaatgct
    14641 tttgcagcta tttgtgcaag tattgtgtca gaaccagttc ctaagtctga agacccagaa
    14701 aacaacttat aagttccatc ttcatccatc ctcatattta ctattgccat gtctatgttg
    14761 gctataccag aaccatgagt tcccacagac attccaacag ccctcacctt attgtttcca
    14821 atatccctaa cagggtactt ttcatcccat ccaataagtt ttttacctct aattatacat
    14881 tcatcaagtg cacaacttct tattggaaaa ttcattattc cgccttcagt ttgttttttt
    14941 ataatattct ttaactttat ttctgttggg tccatattaa gtttatgcgc taattcatca
    15001 attgcacaat caagtgcaaa tgtaccttgt gttgctccat atcctcttaa tgctcctcct
    15061 ggaactaaat tagtatatac agttctccca tcaaatttta ttgcaggtac attattatat
    15121 gttggaagta cattatgacc tgattcagag caaactgaag gtccattatc gccataagcg
    15181 cctgtattgt tcaatgcttt catatctata gcttttatgt ttccttcttt atctgaccca
    15241 atttttatat caaaaaacat ctgatgtcta gtattagtca ttgcaaaagt ttcttctcta
    15301 gtataaatta gttttgctgg tctttttgtc atccaagtta caaatgatgc atatatctct
    15361 gttacagcta tgttttttcc accaaaacct ccacctattc ttggttttat tactctcact
    15421 tttgaaagag gtattcccag tgctttagaa acctgtcttc tcatatgata agctgattgg
    15481 tttgcagaag ttactactaa tctgccattc gtatctatat acgtataagc tctatgagtt
    15541 tccatcatac aatgggcttg tgattgagtc atataagaat gttctactat tacatcactt
    15601 tctttaaact ctttttctac atccccttta cccatttttt ctctcgatac aatatttttt
    15661 gtagcatcca atccaaaatc aaatggacaa aacaaatcat cttcttcatg gattaaaatt
    15721 ttatttcctt ccgattctct tgcatccaat ataggagtca ttacttcata ttcaactttt
    15781 ataagtttca tagctttaat agcagccctt tcatcttcag cggctattat agcaacttca
    15841 tctcctacat atctaactac gtcttcaagt attaattggt catgaggtga tgcttctgga
    15901 tatgactctc caaccattga atatctataa tttggaacat ctttgtaagt gaatatgttt
    15961 actacacctt ttacctttaa tgcatttttt atatctatgt tttttatctt cgcaaaagca
    16021 tgtggacttc taagaagctt aattgttaaa acatctttat gaaaaattaa atcttctgta
    16081 tatattggtt ttccagtaac aatggcttca ctatctattt ttcttacctc tttatttacc
    16141 atcacactca cctccaatac tattatacat tctcactact aaggcttttg ccatatcttt
    16201 tctgtattct ttacttcctc ttatattact tccaaatgaa agttcttcac ttgatacttc
    16261 accagctttt tctatatcat tttctaaact taatatttca cttgctttat aggcaatttt
    16321 tgctcttctt ggtctagcgc ctatcgcaat tttataaata cttccttctt ttaacattgc
    16381 tccatttaat actgcaaaat cacctgtaca ttttcttata gaatcaaata cacctatagc
    16441 atctttttta ggtaatataa cttctattaa tatatctttt tcaagctcat tttctaaaaa
    16501 atcagctaag ttcataaccc cttttttata taacttaacc tttgcatcta ccactagtaa
    16561 tgaaggtatt aaatctgaaa atccatactt agcaaatacg ctagctccta ctctagctcc
    16621 acttctaaat tgaactccta ctatattaga aacagcgttt gaaattaccc cattacagta
    16681 atttttaata accttattta attctaaagt tcttaaactt gtatctgctc caattaatat
    16741 gctatcatca gtttcattta tataatctaa agctaagtct tttaaatcta ttgctgaacc
    16801 aatattttta ctacctagtt ttaaaaatcc acatcctcca agtattatgt tgttttttct
    16861 tgatattagc agttcataag cttcatctaa actttttgga actacatatt cctttatagt
    16921 tatcatactc tctccccata tcaacttaat tttcacttaa aagtctaagt gtttaaatat
    16981 ttatgtattg ctcttaattg acctttatat cctgtacatc tacaaaggtt accatttaca
    17041 taatctataa cttcttcttc tgttggattt tgaagctctc ttttcattgc caagaccatc
    17101 attataaatc caggagcaca aaatccacac tggtcagccc cttcgtctgc aagaaaatct
    17161 ccaaacttct ttgcttcatc caagacaccc tcaagtgttg taatatgctg accttctact
    17221 ctagcagtaa gataattaca tgaaagcacg gccttgtcat ttaccatcac tgtacataac
    17281 ccacatgagc ctgtatcaca ccctttttta acacttacat atccattttc tcttaatgta
    17341 tctgctaaaa aatcatctgg tcttatactt aattcttttt ctttattatt tatggtacat
    17401 ttgataatca aataaatcac ctcaaaactc atatttttaa gctaaagttt tactatactt
    17461 ttttatgaat aaattacatt tattaataaa ggctattcca tttatgacct tccattctat
    17521 tttttatagt tcctcttaca caaagtctct cagctgtatc ttgagcatct tttaatgctt
    17581 tctcttcatt agctgtcaat atttttgaat cttccattat tatatttcca tctactataa
    17641 cactctctat atttttcata ctagaagaat atactaatgt agataccgga ttatgcatag
    17701 gtatcgcttt tggtgaaagc attggattaa atattaataa gtctgctttt ttacctatct
    17761 ccaatgaacc tatctcatct tccattccaa tagctcttgc tccatctata gttgccaact
    17821 caagaacttt ttctgctgac attgctaatg ggtcacactt attaacttta tgttgaagtg
    17881 ctgttaattt cataagttca agcatatctt gagagttatt actagcggct ccatctactc
    17941 ctaaactaac tgttattcct tttttaagca tttctggcac tggtgcaaca cctgaagata
    18001 agtacatatt acttgctgta ttatgagaca ctttcatatc gtatttttta gtaagttcca
    18061 tatctttttc agttagatac acacaatgta ccataagcac atttggtcca agtattccta
    18121 atttttctaa aacatctatg tcatattgcc catgcaattc ttttgctgct tctctatcaa
    18181 aaggagtctc tgatatatgt actgtaaata aagcatcatc atattctttt actactctcc
    18241 atagcatttc aagcatttct tgagaatttg accatattgc tgcaggagct actcctattt
    18301 tgattcttcc attttctgta ttatggtgtt tttcaaacaa tcttcttaca tctttttcaa
    18361 ccgtttctac atcttgcatt attccaggat gaactccaaa ttgagctcct gtattcatac
    18421 atcctcttcc aagtattcct cttattccta attctttata agcatctatt attccatcac
    18481 aaagacctgg cttactatga ggatacatgt agtcaaccat tgttgttata ccacttctaa
    18541 gtccttcaat acatccaagc attgcagcat cataagtatc ttttggctct aaatagttag
    18601 ctgctggaaa tgtcatagtt tctaaccagt ctttaagtac catatcatct cccaatcctt
    18661 ttaataaagt ttggaataaa tgattatgtg tatttataaa acctgggaat aaaactttac
    18721 ctttagcatc tataattttt ttaacatcag tatatttact ttctatctct ttagaatttc
    18781 caatatcagc aatcttgtta tcttttacta ctaatgcccc atcaaaaata acttctctct
    18841 ctttattcac agttactatt atggcattct taataagtat atccatcatt cttatttccc
    18901 cccgcattat ttagtaattt ttcttttaat atattgacct gttggatgtt ctttaacatt
    18961 acaactttgt actacatgat ttcctctcaa aaatacatct tcaactttac atttaacctt
    19021 aaatccttca tatggagtat aatctacatt ttgtttttga gttttataac taattgtttc
    19081 ttctttattg atatttaaaa tgactatatc tgcatcactt cctacagcta tctcaccttt
    19141 tttaggatac attccaaata tttttgcagc attcgtagaa gtaacttcca caaacttatt
    19201 tgcacttatt ctattttcta agactccata tgtatataaa agtgctaacc tatgttcaac
    19261 accaggtgct ccatttggta tcttactaaa atcatcaatt cccaagtctt tttgcccctt
    19321 aaaattaaat gaacagtgat ctgtgccaac tgtttgaata tctccactag acaatccttc
    19381 ccaaaggtaa tttatgtctt ctttttttct taaaggagga gacattacat acttagcacc
    19441 ctcaaattta tccttattat ataaattgtc ttctaataat agatactgtg ggcatgtttc
    19501 tactatcata tctatatttt tttctctagc catttttaca gtttcaagtg actccctaca
    19561 acttaagtgg actacatagg attttgaatt agataattta gttatatcag caagtcttga
    19621 aacagactct ttctcaacta tgttaggtct tgtaagtgga tgatattttg gctccaaatt
    19681 accattttgt atattttctt ctatcaatac atctagtaaa tccccatttt cacaatgaaa
    19741 tccaactata caacctaaat cccttgcttt ctttaaaacc ctgtatattg ttccatcatc
    19801 tactttcatg ccatcatatg ccatatacat cttaaaagat actatcccat ccgaaataag
    19861 tttttccata tgattaaatg tatctttatt taaacatgta attgtcatat gaaaaccata
    19921 atcacaataa caatttccac ttgctttttt atgatatgct tctacacctt gcagtaggtt
    19981 ttccccctca ttggcttctg caaaatctag tattgtagta gttcctccag ctatagctgc
    20041 tcttgttcct gtttcaaaat tatctgcagt tgtaatagaa cctgcattca tatcaaaatg
    20101 agtatgtgtg tctattccac caggaattac aattttacct gtagcatcaa taaccttatc
    20161 accatttatt tctaagttat ttcctatttc aactatctct tcatcttcta tccttaaatc
    20221 acttatataa gtcttatcag aggtaattat agttccacct cttagtattg ttcccatata
    20281 tacctcctaa cttttaagct ttaaagtatt ttctaagtat tgtaaaactt tatttaaaat
    20341 tgtattttct aaaggtgcta tattcagcac ctctagacta tatttaaata atttattgtg
    20401 aactaaatat tattttccgt atacagattt taatattcca tagtaacctt ctgttcctat
    20461 aaataactgt tcttgctcta tatactcatc tattgtgtga gcaagatttt ccttagaagg
    20521 accaaatcct atagttttta ttccagcttc acctgcatag tgacttccat tcgtacagaa
    20581 tgagtattga gttatttctg aatctattcc agcttctttt aatcccttat atgctgcttg
    20641 aacaaattca tcttcttcgt catataacca acctgggaag aatctttcac tttctatagt
    20701 atttcctgta tagcaatcag ctttttcaac tgcataagaa acttttgcat ttaattctgg
    20761 gtcttctttc atcatttcat ctaataaagc ttgtattgga gctaatacgc cttctcttgt
    20821 ttctccaact aataatcttc tatcaaaagt agctttgcaa taatctggca ctactgatgc
    20881 tcctggatat ggagaagatt ttatatctgt taaaactaat attccatcac ctaaaactgg
    20941 atgagttgga ggtactaatt gttgtatctt ttggattaca ttagccattt tataaactgc
    21001 atttacacct ttttctggat tagcagagtg agctggttta ccaaaagttt ctactactat
    21061 ttctcctcta cctctctgac caatctttaa gtttaactct gaagactcac ctattacaac
    21121 atagtcaggt tgaacagcct tacttatctc tctagccgaa acaccttcaa atatttcttc
    21181 atgaacaaca cctgctacat atagttctcc agcaaaatct ctattagtgt ctttagcaaa
    21241 atacgctaca gcagacatca ttgcagtata ttgacctttc atgtcagaag ttcctctacc
    21301 atatatcttt ccatcaacta tttttccttc aaaaggagga acactccatt tacttgcatc
    21361 tggaactgga actgtatcta tatgtccatc aaataatatt ttcttacctg gcttgttacc
    21421 ttttatacat cctactatat ttccatatct atctcttgac caactatcaa aacctaattt
    21481 ttcaaaagac tcttctattg cttttacaac accttcttca tttccagaag aactaggatt
    21541 ttgaattaat ttttggcata tttcagttac ttcttgtttt ctttgttcgt ttaacatttc
    21601 attatccccc tagatttttt ataatgtatg tattttatat acttatatat tttctaaatt
    21661 ttagaactta tatatcttct aaatatgtaa accaatatct aataattgca ttttagtaat
    21721 tccttatata cttggatatt ctccatccca aactatactt ctatatttgt cagggtcagt
    21781 atctccttct gtgcttatta aaagtattct tgaattttca tctaatttta aatcttttct
    21841 taaatctgct aaatcttctc tttccatagc tgctactaaa agaccagttg taactgctcc
    21901 agattctcca gaaattacct tttcatcacc atttaaagga ttacctaatg ttctcatacc
    21961 cttagcagaa acccagtctg gtgctgaaac aaatgctgct gcatgatttt ttaatacttc
    22021 aaatcctata gtatttggct ctccacaagc aagccctgcc attatagttg gcatatctcc
    22081 tccaacaaat cttggttttc catctccagc ttctgctgat ttatagtaac aatcagcttc
    22141 atcagcctct actactactg ttattgggca ttcatcatat attgaagcaa catacccttg
    22201 aactgcacca gcaagtgaac caactcctgc ttgaacaaat acgtgtgttg gtctatctac
    22261 tccatattct tttaattgct ctatagcttc ttgagccata gttccatatc cttgcattat
    22321 ccacgctggt atttcttcat atccgtccca tgctgtatct tgaaccatta ctccatggtc
    22381 atcagcttct gcataatcat tagctaatct tactgcatca tcatagttta agtctgttat
    22441 actagcatct gcaccttctc ctttaatttt atttaatcta aattcagaag aaccttttgg
    22501 cattaataca acagattttt gacctaattt attagctgtc caagcaactc ctctaccgtg
    22561 atttccatct gtagctgtaa agaaagttat ttctcctaat ttttctttta tttcttttga
    22621 agttaatttg tcatacccta actcagatat atctgtatct aatctttgag ctaagtatct
    22681 acccatagaa taagaaccac ctaatacttt aaatgcattt aatccaaatc tataagattc
    22741 atcttttaca tatactcctg caacacctaa tttttttgct aaaccttcta ggtttgctaa
    22801 tggagtttct ttatattgag gaaagctttt gtgaaaattt ctaaccttag ttatttcttc
    22861 ttcatttaaa aatttgatac aattttcctt atcgcccttt ggcaaattat ttactttcca
    22921 tttaatttct tttaacatct aaaatacctc caaattattg ttaaattttt atactttaat
    22981 atataagcaa ttaacatgcc aacactaaat atatactaga tatttttcta tgactcttta
    23041 gtatagaaat tgcaatgctt ttattatttt ttcttttcta tctttagttc atacaatgta
    23101 tgtagaattt aataactaaa aaaccttttc tatcttctca ctttttaatt ctcattttta
    23161 aaatttaaaa ataaatctca aaacactttg tttctatatt ttttaatata aaatctataa
    23221 aatctaaatt aaaacataaa atagtgatgc aataatctat tacatcacta tttgtatata
    23281 ttcaataata taataaatct ttagtggtct ctaagaggtg atttttcatc ttttttaaca
    23341 tctaattctt cttttacgac attccatttt tcaagaccaa acttagaaac cataactgcc
    23401 tctgctgcac cttttccaag tctttttact gtgtccatac ctgtctcatc ctcttgggca
    23461 ccttttgctt ttccatcttt actccatatt gtaccaccta tatagcatcc acctaaacct
    23521 ccagacacta acatttcatg cattaggaag aaatttatta taggaagttt tgtcaattct
    23581 tggccaccat atctagttcc accagtagtt atagctgcac caaccttatt ttgaagtttt
    23641 cctggatgaa ctaaatacat tggacgaagt ctattaaata ctgctgtaag ttgagcagtt
    23701 atattcatat cataaactgg agaacctact ataattccat ctgcctccaa tattttttgc
    23761 tctaattctt ggatatcatc ttttataata cacatagttt cttttcttat acatgcatca
    23821 caatgtacac aaggacttat ttttttccct ctaactgacc aatactcagt ttctatacca
    23881 ggtatagttt ctgcttcttt caaagcttct aacactgcat attctgttgc tcctttacgt
    23941 ggacttccac aaatacctaa tatctttgcc ataataatat ctcctcacca aataaatcta
    24001 tttttattat ctatttacaa atacaataaa ttgttatttc tgctttaatt tatactattt
    24061 taattttatt ggtaatgaat gtatctctac atcagttgca ttatatactg catttgcaac
    24121 agctggcgca actggtacaa cggcacattc tccaatactc ttaccaccaa aaggcccagc
    24181 tttttcataa ccatctacaa atgcaacttg acattttggc atatctacag ttctaaataa
    24241 tttatatgtt ttaaaatcag tagctttagg tctaccttgt tcatcaaatg ccaattcttc
    24301 actcaatgcg tatcctagac ccatatgaat cccaccttct aattgtcctt ctaaatttag
    24361 aggatttata actctaccaa catcatgtac agctacaaaa tcaactactt ttatatcctt
    24421 agtttcttta tctactaaaa cttcagcaaa atgtacacca taagaagtac gtccagctgg
    24481 tgaagaataa tcttcaacaa cagttaactc tcttaatgat ttactttgac tatatactgc
    24541 gacatcagaa agtgatgctt ttacattttc atcaagttta ctaattacac atccattgtc
    24601 tagatataaa tcttcttttg atgtttcaag taatttttct gcttcttcta atataagatt
    24661 tttcaatttc tctgctgtct ttttagctcc tccaccttct acaaataccc ctctacttgc
    24721 atagtcacca aggttgaatg tacatgcatc cgtatcagtt tcaaatgtat caactttatc
    24781 aggtgttatt cctaaaactt cagctaccat cattgtttgc atagttacaa caccattacc
    24841 catatcatga gctcctgtta gcagtgtcaa cgtaccatct tcatttaatt taagagtcaa
    24901 tgtaacaaca tctctatgtg caccaaaaac tccattacca tgtgcaccta ttgccatacc
    24961 tatacctctt aaatattttc cttcttcttt tggaagtttt ttcttttcat cccacttaaa
    25021 catcttctta ccttgctcta tacaatccaa tactctagga tttccaagag aaccgtggaa
    25081 gattatatcg acatcatctg gctctactgc atttttattt tgaaaatcga ctaaatccat
    25141 acctatttcc tttgctattt tcgcaaattg agcttgttga gccataaata tttgaggtga
    25201 cccatagcct ctcatagctc ctgctattgg tgtatttgta tatacaggca tcccagtaaa
    25261 ctttatattt ggtattttat aaactttaaa tactttatga ctaagtgctc ctataacatt
    25321 taaagcactt gatgcatatg ctcctgtatt tgtatatatt tttatgtctt gtgctattac
    25381 ttcaccatct ttatttacac cagtttttaa ttttacaaaa gacccatgac gagttcttgt
    25441 tgatatcata gattcctttc ttgtaagaac cattttaact ggtcttcttg tcatttttga
    25501 taatgcggct gctactggtt caattgtaag ttctaatttt ccaccaaatg agcctccaat
    25561 agcaggtctt ataactctta ctttatttaa tgacatccca aaaatttgag atagtattat
    25621 tctaaatcca aatgtatttt ggcaaggtgt atgtacagtt aatttatcat tataatcata
    25681 gtgtgcaatt acactatgag tctctattgc actatgatgt attgctggag tagagtattc
    25741 atcttcaaat atatagtcac attccttgaa gcctttttct acatctcccc catttatgtt
    25801 gttttgagaa actatatttg aatctccatg tatgcagata gcatcttctt ttattgcatc
    25861 ttgtatagta aatacagctg gcaattcttc atattcaact tttataagtt ttacagcttt
    25921 ctctgctatt tctggagtct ctgcagctac tgctgcaaca cggtcaccaa caaatctaac
    25981 tgtatctgaa aatataactt cattttcagg tattttgtgc tcataaaatc ttaatgaacc
    26041 attgtatttt ctttgtgatg tattgagata agtagctata gctctaacac ctactacttt
    26101 ctcagcttca cttgtatcta tactttttat ttttgcatgt gctacagggc ttaaaagcat
    26161 cttagcgtaa agtacatttt gtggtttcat atcagccacg tatttcattt gaccagtaac
    26221 ttttaaagct gcatctttta gagggtatga ttttcctatt accttttcca taattatcta
    26281 ccccctaatc tagctgcaga taattttaca gcttctataa tctttacata tcctgtgcat
    26341 ctacagagat tttctttaaa agcttctcta atttcatctt cattaggaga tgcatttcta
    26401 tttaaaagag cttgtgttgt tataatcata ccaggagtac aatatccaca ttgtacagct
    26461 ccaacttcta taaaagcttc ttgtattgga tgaagatttt ctccattagc aaaactttct
    26521 atagtgtata taactttacc ttcgcagttt tttgcaagaa gtttacaaga tttcatgtca
    26581 actccatcta tcaaaacttt acatgctcca caactgccac tattacaacc ttgtttcgct
    26641 ccagttagat ttaatttttc acgaagtaca tgcaaaagag tttcattctt ttcaacttct
    26701 atttcataca tgtaatcatt aatatttaat tttatttttt ccattttctc ctcctacaga
    26761 taaactaatg ttgtaataga atattattac aatcttattt taatattagt ataagctatt
    26821 ccacttatgt ccttccattc tattagttac attagctctc ttacataatt cttctgctgc
    26881 atgttgtgca ttaagcaaca cttgttcttc actttcaatt gtagttactt ttccattttc
    26941 aagtattaca tttccatcaa ctaaaacact ctctacattg tgcatactag ctgagtatac
    27001 caaagttgat acaggattgt gaagaggtat tgattttgga gaaagcattg agttaaatat
    27061 tactaggtca gcttttttcc caatctccaa agaacctatt tcatcttcca ttctaagagt
    27121 tcttgctccc tcaattgtag ccatttcaag aactttctct gcagaaattg ccagagggtc
    27181 acaattattt actttgtgtt gtaaagctgt tagtttcata agctctacca tatcttgtgc
    27241 gttattactt gctgcaccgt caagacctaa actcacattt ataccttttt ttaacatttc
    27301 tggcacaggt gcaacaccag aagcaagata catattactt gctacattat gagaaacttt
    27361 tatgtcatac tttttaagca tttccatgtc ttcatcagtt atacatacac aatgtactgc
    27421 tacaacttct ggacctacta taccccattt ttcaagtaat tttatatcta tttctccatg
    27481 tatatccttt gttgctgttc ttgcaaattc tgtttcagat atatgaactg taaaatatga
    27541 atcatattct ttaactatat tccaaagcat cttacccatt tcttcagata tagcccacat
    27601 tgaagaagga gctacacaga tttttattct tccattttct gaattatgat atttttcgaa
    27661 tacccttctc aaatcttttt caaccgtttc cacatcttct ataagctctt tgtgaatacc
    27721 taaatctata caacctctac ctacaacccc tcttatgcct aaatctttat atgcctttac
    27781 tattccatct gtaagtcctg gtctattgtg agtatgcata taatcaacca ttgtagttat
    27841 accacttttt aaaccttcca tacatccaag cattgcagca tcataagtat cttgttctgt
    27901 taagaatttt gctgatggaa acatcattgt atttaaccac tcatgaagtg ccatatcatc
    27961 acctaaacct tttaataaca cttggaacag gtgattatga gtatttataa agccagggaa
    28021 tattactttt ccattagcat ctataacttt tttagcatca agatacttag gctcgatatc
    28081 aactgtattt cctatgtcca agattctgtc accttgaata gctattgctc catcaaatat
    28141 aacatctctg tctttattaa ctgtaacaat tattgcattt tttattagta tatcaatcat
    28201 cttaaatccc cctttgaata ctttcattac aacattttac catatggttt tctcatatta
    28261 tatctaatac atttatccaa tattttcttc aagatttgaa gtaacgtttt cagcactttt
    28321 acgtgacttt aatttaaata atgtttgaag taatatagct attattgctc cagaaactat
    28381 acttgaccct ccaaggacag ttccaattgt ttctgggaat tggtctaaaa cttgtggagc
    28441 agttgtaaga cccatacttg ttgctataga tacacctgct ataagattgt tttcttcagt
    28501 gaatccatcc atactcataa tagagaaacc agacattgct attgatgaga aaactactaa
    28561 agttgctcca ccaacaacac aagatggtat agttgtcatt attgcaccca atgctggaga
    28621 tatccctgct agtaataata caagtgcccc tagtgctatt acaaatctac ttgtaacttt
    28681 gttcatagat acaattgctg tattttggct aaatactcca gttggaagag ctgcaaatag
    28741 tgatgaaatt atagaagtta tagaatttcc taatacaact gatgctaatt cttcgtcagt
    28801 tacctctcta tccattgctc ctactgtagc tattgtacag gcacccatca tatcagctat
    28861 acctattatg taaataatag taaacattac tattaactct ggtctaaatt ctaatccaaa
    28921 agctgctggt gttggtaaag atactatagc tgctccttga acggctgaga aatcaaccaa
    28981 tcctaaaact aaagatatag cataacctac taatattcct attaatattg aagaattttt
    29041 tactaaacct ttaccgtatt tatttatcat tattattaca aaagcaacta taactcctac
    29101 tgtgaagttt attgggcttc caaatgtttg tgtgccttct cctccagcta aattctttat
    29161 agctgttgcg aatagtccaa gtcccataca tgctattata gttccagaaa ctattggagt
    29221 gaatatatgt ctaattttct taactccaaa tcctacaaag aatacgatta ccccagcagc
    29281 aatctgtgct ccaaatagag ctgctaaacc atctttagct gctactgaaa gacaagctcc
    29341 taaaaataca taactcattc ccatcattac aggtaatctt gaacctaact taaatccttt
    29401 aaataaaggt attggatata actgtaaaaa cgttgctaaa cctgctgcta acatagaacc
    29461 ctgaatcaac attgttgctt gcccctggtt aagtcctacc acgtttgcta ttaatatcgc
    29521 aggtaccata tttcctacta tcattgctaa cagatgttgt aaggccaaag gtattgattc
    29581 ctttagtggt ggtatcccat cgacatcata ttttgaagta ttacgtgttt tcataaaata
    29641 aatcctccca tacataaata tcttgactaa atatttttat aattattttc tataaatatt
    29701 tttatgacca tgaatttatt gctcaaccga taaacacagc taaactgagc tatttttata
    29761 aaaaattaac aaatttctaa atattgcctc cccgattttc aacttaaatg aacattaatt
    29821 gcctggtata tatttatttg ttaaattttt tattaaaatg aatagctatc aaaaataatc
    29881 taacaatctc atactaaata atttaaacaa ttcttttaaa ttattatatc ttaattagtc
    29941 tcttccataa cagctctttc tttagcctca tcctctagac ttttatttgg tattattaga
    30001 tttaaaacga atgcaaccaa tgttgcaatt actattggag attctccaaa tactaacttt
    30061 acaaatgaag gaaatgcctc ttgggctgct gggactgatg ttattcccat gcctaaggca
    30121 attgccaaac caacaatggt aatatttctt gatgacaact cttctgtaat aattaacttt
    30181 atacctgtca ttgttattat actaaatata gatattgtag ctcctcctaa aacagaatat
    30241 ggtatagtag tcattaatgc accaaattta ggcacaaacc ccgacaataa cataaatata
    30301 ccagctattc caagcacaaa tctacttatt actttgttca tagctaccat ccccacgttt
    30361 tggctatatg atgatggtgg taaacctcca aacaaagctc ctatcatagt acaaattcca
    30421 cttcctatta ctccacttga taattcctta tctgtgatat tcctatccat gcctcccatt
    30481 gtagtagctg ataagtctcc aattgcttga acagcattga ttatacttac aattactact
    30541 gagattatta caggcatatc aaattccatc ccaaattcaa gcggtttagg tatcgcaaac
    30601 caagttgcct ctctaatagg gtcaaaattt attataccca gaactaaaga tacacaatat
    30661 ccaactataa ttcccaaaaa tattgctgcc aattttgcat atccttttgc aaattgacta
    30721 agacctataa ctaccactaa tgttatagcc gctactgccc agttttgcat agaggcataa
    30781 gtaggactat ttacaccacc tgccatataa tttattgcta taggatacaa agataatcca
    30841 attgtaaaaa ccactgttcc tgcaactata ttcggaaaaa attttcttat cttttttatg
    30901 aatatcccta ttaatactgt agccactccc cctattaatt gtgcacccaa aatgcttgct
    30961 aatccataat ttcctccgac tgctacaagt gttggtacat aagtaaaacc aactccaaaa
    31021 attataggca atcttgaacc aatatttcct attggatata gttgtataag tgttgatata
    31081 ccagctatta ttaatgcata ttgcactaaa agtgttattt gtgtagggct aacacccaca
    31141 gctcctccta cgactatagg tactgtaaca gttccaacta tcattgctag tatatgttgc
    31201 attgatagtg gcaaacactt taaaattggt ggccttccat caatatcaaa catagaaaca
    31261 ttcttttgat atttactcaa ggttatcact cccaactatt ttttaatgac agttattatt
    31321 atctcacaca acatcctttc tttttttatt ttgtcatctc aacttaatat gaagcaatta
    31381 taatgccaat tttttaacat aattgtttta catatataat ttttattata tttgttagta
    31441 tttgataatt tattaaagca tttatttttt taaattcttt taaatttttt ttatttttgg
    31501 ataataaaat gctattacac aaaaaaacac ttagaaaata gttttccaag tgttttttat
    31561 caattttata atttcaaatt ttagaattga gaataaaaag cctaattatt atacatctat
    31621 ttttctgtac aatgtagcta gtgatattcc aagttttttg gcagccagtt ttttagactt
    31681 agtatcattt ccgtaaaact ttaacacttt ctttatatag gctctttcaa actcttcaag
    31741 tgtaagtatg tcttgttcca tacttatctc atagtcactt tcctcaagta actttatatt
    31801 tatattattt aacttaaaat attcaagtat ctttctattt attattcctt tatgtattat
    31861 tccatcttcc tcaagaaggt ttaatgccag ttctatagta ttttccaact ctctaatatt
    31921 tcctggccaa ggatacttaa gcaacatttg ttccacatct ggctctatat ggtacacgtt
    31981 tttcttcatc tttctcgaat atttgtctat aaaattgttt attaatattt gtatatcgtc
    32041 tcctctttct ctaagtggag gcacttctaa aggtattaca ttcaatctat agtataagtc
    32101 ttctctaaat ttattttcct taaccaactc aaataaatct ctattagtag ctgatatgat
    32161 tctaacatct atatcaatta gttcatttga acctattctc gtaaacttct tttcctgtaa
    32221 taccctcaat aactttgatt gtagttgaat tggcatatct cctatctcat ctaaaaatac
    32281 aacccctcca ttggccaatt caaacttacc aattttacct tttgaatctg ctccactaaa
    32341 agctcctttt gtatatccaa aaagttcact ttctagtaaa ggttctggta tagcagcaca
    32401 gtttatagca acgaatgttt tattccctct gtttcctgcg agatgaatgg ctcttgctat
    32461 taattctttt ccagtgccac tttctccagt tatagctaca gtagaatcac tatttccaat
    32521 tttacaaatt ctattcttaa gagcacgcat tacatcagac tctccaatta tggagtctac
    32581 tgttgttgtt ccccaaatat tatatacttc cattccacca tacattactg aatcactgtg
    32641 tttgtccata aaatatcaac tccaaataag tattctatat aataatcatt cacattatct
    32701 attta
//
LOCUS       DAJMZY010000035        32636 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.035, whole genome shotgun sequence.
ACCESSION   DAJMZY010000035 DAJMZY010000000
VERSION     DAJMZY010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 32636)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32636)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32636
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.035"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            578..1906
                     /locus_tag="OE968_001630"
     CDS             578..1906
                     /locus_tag="OE968_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCP7218912.1"
                     /translation="MGSNELKKTLGVSAALSTVVGSVIGAGVFFKPQAVYTLTGGAPG
                     LGILAWLIAGIITITAGLTAAEVSVAIPKTGGMMVYIKEIYGEKLGFLTGWMQIVLFY
                     PGMMAALGVIFGEQASALIGSPSLLLPIAIGIIVIVAGLNMLGSKTGGVIQTVSTICK
                     LIPLILIMVVGFIKGGGNNPILTPMVGEGLSLGSVLGQVLIAILFAFDGWMNVGTLAG
                     EMKNPGKDLPKAIIGGLSVVMAVYFIINLAYLWVLPANELANYASPASAVAEVIFGSM
                     GGKIISVGILISVFGALNGFLLTGSRVAYTLATDKTLPKYGIFSKLNSAQVPANAIAL
                     VSVIASIYALSGQFNLLTDLAVFATWIFYVLTFIGVMKLRKTHPNIPREYKVPLYPIV
                     PIIAIASGIFVVVNQLCFAGMKTTMISIGGLVITAIGLPVYAYMTRGVKR"
     gene            2659..3492
                     /locus_tag="OE968_001631"
     CDS             2659..3492
                     /locus_tag="OE968_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase"
                     /protein_id="HCP7218913.1"
                     /translation="MRNKKKKINRKKLYLLLSAIVVCLAFIVVGVRVSSLNMKENEIS
                     RNAKLSSSTITDIVSNTSIEVSKGPSKSSGKIAYITIDDGPSKFTDEMIKTLNKYNVK
                     ATFFMIDGNMKEYPQQVKNIIKNGNTAGFHSVSHDIHKLYVTSTSAKEEFDTNDQTFY
                     KITGKHSKVIRIPYGSKPYTPQASYQALVDAGYKIWDWDLDTEDWRSNSSQIVQNVKN
                     HIKNRKGEDKDQLVVLMHEKKQSAEALDSVLKFLSDEGYEFAPVDQNQIPKNYWLRNL
                     E"
     gene            3585..4517
                     /locus_tag="OE968_001632"
     CDS             3585..4517
                     /locus_tag="OE968_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HCP7218914.1"
                     /translation="MVGILSLMMVGCNKSLAKVNDVEITKEQYKKTKAVLSATNNYIN
                     GQSLDELEKTLDKKGRNKLENVIISFMVDNELLYQEAKDKGLTPSKSEVDSKYQELED
                     KMNLNTSYKEKMDKAGVDKDYLKQEISRDLAIDKNKKAFEDRINISDNDMEAYYTSHK
                     KDFNVEEVSASQILISTLDKNKKEVSKDKKEALKKKADNILTKIKNGESFESLAKKYS
                     DDKATGKNGGQLGYFTKDDKNAEFTKEVFKLKKNEVSNVFETSYGYHIVKVTDKRERQ
                     KSFNECQSLIRESILNEKYIEHIKKLNEDAKIDR"
     gene            4569..5051
                     /locus_tag="OE968_001633"
     CDS             4569..5051
                     /locus_tag="OE968_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HCP7218915.1"
                     /translation="MFKSLKRTKVEKYIIDNKDSFYRIAYSYTKNEEDALDVVQEAMY
                     KALYSVENIKEVNYIKTWFYKILVRTSIDFIRKNRKYNNMTDIDLIDETGEYDKYTDL
                     DLRRALEELPIEYKSIIILRFFEDLKIEEVAIILDENVNTVKTRLYTALKKLKLKIEE
                     "
     gene            5063..5932
                     /locus_tag="OE968_001634"
     CDS             5063..5932
                     /locus_tag="OE968_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HCP7218916.1"
                     /translation="MTSKERLNKLKDEYHKIPIPKKLDTIINHEKIENIYREKNKKVN
                     RLRFKVAIAFACIFTVLVNISPVFADNFSKIPVIGAIVEVITIKNYSLKSENYEAEID
                     IPKIRGLKDKNLEQRLNSSFMEDGKRLYHQFQERMEKIQSSKNKGYKSLSLSYSVKNN
                     SKKFLSIEMTKNEIEASSYVSKVHYTIDKKRQIVLTLPMLFKDDKYIKVISDNIKEQM
                     REQMKKDSTKSYFIDQKKDLPVEDFKTINKYQDFYFNKNEDLVICFDEYEVAPGYMGA
                     VEFVIPYKVIKDL"
     gene            5975..6730
                     /locus_tag="OE968_001635"
     CDS             5975..6730
                     /locus_tag="OE968_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HCP7218917.1"
                     /translation="MTTYKKLKKSIFKIAIFSICLLVSLVDTNPIFAGSSFNETSNSD
                     TIKVLNAKSINFKQDNYEVNVSIPKIKGLKDKTLENKLNNEFLQDGKKIYSEFQNKMK
                     KENNKGHRYLNVIHNVKNNSKDFLSIEMTKEEIEASSSITKKHYTVDKNRGILLNLPI
                     FFKDSRYIRAISDNIKEQMRNQIKKDDTKSYFIDQDKDSPVKDFESINKYQDFYFNKN
                     GNLVISFDEYEVAPGYMGAVEFVIPNKVIKRLR"
     gene            6772..7593
                     /locus_tag="OE968_001636"
     CDS             6772..7593
                     /locus_tag="OE968_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine dehydrogenase accessory factor"
                     /protein_id="HCP7218918.1"
                     /translation="MNIYEQAIRLIENNEDFAFATITSHSGSTPRETGAMMIVKNDST
                     IFGSVGGGSVEAECIKHAINVIKNRESMLYKFTLNKSDVAKLGMICGGTGEIQIDFID
                     SKLKSNIEKFNKRLKENTSKAYIFGAGHISRDVAVILSLLEFRTVVIDDREEFANHER
                     FPESEVVVLDSFENIPDFPTDENSYIIILTRGHLYDSSALEWALKREAGYIGMIGSRT
                     KIGLTYEKLMKKGFKKEELSKVHAPIGIKLNAQTPAEIAVCIAAELINCRANKEK"
     gene            7598..8359
                     /locus_tag="OE968_001637"
     CDS             7598..8359
                     /locus_tag="OE968_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M48 family metallopeptidase"
                     /protein_id="HCP7218919.1"
                     /translation="MNTGSKDIDTLKVNFRGIEIKAVLVYKNRKNISIKIDPFGKITV
                     MSPPKISKKIIKDIIIEKGDWILKKSEKCKGREEVYKQRMFITGEKFLYLGEEYHLVI
                     KELLRDSVKKSNCRITINEYQIVVQTNDTSTDFIKKSLKSWYKMESERIVLERIDFLK
                     LNCEIMKQLVPASVKVKEQNKRWGSCTAQKNIYINSKISMARLDVIDYVIIHEFSHLA
                     HMNHSKKFYDLVKSIMPDYKDKENWLKINGYKIII"
     misc_binding    8520..8777
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            8890..9129
                     /locus_tag="OE968_001638"
     CDS             8890..9129
                     /locus_tag="OE968_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HCP7218920.1"
                     /translation="MENTVYAKLNQGIDSFLRVAMTLRRREVDIQSISMTVDNMNNSG
                     IKLIVNEEKTSLDSVLNHMKKLHDIREITVERMRH"
     gene            9433..10428
                     /gene="ilvC"
                     /locus_tag="OE968_001639"
     CDS             9433..10428
                     /gene="ilvC"
                     /locus_tag="OE968_001639"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HCP7218921.1"
                     /translation="MKMARMYYEKDVDLEVLKNKKVAVLGYGSQGHAHAQNLRDNGVH
                     VVIGLYDGSKSAQKAKEDGFEVKSVAEATKESDLTMMLMPDEKQKKVYEESVKDNLKE
                     GQTLAFAHGFNIHYNQVQPPEFVDVVMVAPKGPGHLVRNVFTKGSGVPALFAVYQDYT
                     KKATETVLAYAKGIGATRAGVLETTFKEETETDLFGEQSVLCGGISELIKLGYKTLVD
                     AGYQKEVAYFECLHEMKLIVDLIYEGGFERMRYSISDTAEYGDYVSGKRVITDAAKQG
                     MQNVLEDIQNGKFAKAWIKENEEGRENFLKTREEEYNTEIAEVGRNLRSMMSFLK"
     gene            10481..12169
                     /gene="ilvB"
                     /locus_tag="OE968_001640"
     CDS             10481..12169
                     /gene="ilvB"
                     /locus_tag="OE968_001640"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biosynthetic-type acetolactate synthase large
                     subunit"
                     /protein_id="HCP7218922.1"
                     /translation="MSGAKVILECLKKEGIDTIFGYPGGAVIPLYDALYDYSDDFKHI
                     RTSHEQGLVHAADGYARSTNTVGVCFTTSGPGATNAITGIATAFMDSSPMVVISGQVP
                     TSLLGKDSFQEIDITGATLSMTKHNYLVRNTKELVPTIKEAFRVANSGRKGPVLVDVP
                     KDLFLAEMDFSGEDYDLCQIDDYMDYKSDFDLDDETNIKLLNEAIDIIKESKKPIIYA
                     GGGVKSSDSEEILEKFATKIDTPVLNTLMGLGNIDRKNELSLGMVGMHGSRESNLALS
                     NSDLVIAIGARFSDRVISKSSEFAKNAKIIHIDIDPSEISKNIESNVSLVGDVKLVLS
                     LLIERVESKNNSNWKEEIKRFRKSEGVQTYEFHPQNILKKINEKYETLKKPTVVVTDV
                     GQHQMWAAKYWNFKGNKSFITSAGLGTMGFGLGAAIGTKVGNVDKNVVLVTGDGSFRM
                     NCNELATVANYNVPMLILLLNNRTLGMVRQWQKLFSNQRYSQTDINENVDYVKLVNAY
                     NIDGYKVSSMEELGKALDMIDFNKPVFLQCDIDKDYDVYPIVAPNDALENLICN"
     gene            complement(12530..13660)
                     /locus_tag="OE968_001641"
     CDS             complement(12530..13660)
                     /locus_tag="OE968_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HCP7218923.1"
                     /translation="MKGGVRKRSNKWYYYFDLGIVEGKRKKVERVGGNTKKEAEKALR
                     EALNEYENSGIVFEESNISLSDYLDFWYKEYVLLNCKYNTQESYRINIEKHIKPKLGA
                     YKVKALTPAILQNFINRKYKEDYSQNTLQVLKAILHRSLKSAVHPYKHIRENPMQYVS
                     IPKTKSKTETNKIKTITLEEFNQILNIFPQDSFQRIVLLIGFHTGMRRGEIIALKWDN
                     IDLDNKTITVRHTLIKKPNGMFELGQPKTESSCRTIFTGDTLIKALKEHKLYQKKMKL
                     KYGEFYFDSDWVCTKENGQQVNTHTLDTIVRQIRVALNNDFHFHSLRHAHATLLLENG
                     ANIKDIQNRLGHSQLSTTMDTYSHVTDKMKNETVDIFEKITN"
     gene            complement(13900..14406)
                     /locus_tag="OE968_001642"
     CDS             complement(13900..14406)
                     /locus_tag="OE968_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HCP7218924.1"
                     /translation="MNKLDALLDLANNEEIEIYYTDKIADDIKGLYINRQGLKIISLL
                     NSLKQNNAKLIEILAEELGHHFTSVGNYVSSKNSYKNKILIDKTENKALKWACEFLIT
                     EEEIIHVINSHATSVYEIAEELQVSINFLLKRLEFLSKKKSMLDLGNNRFLVLTNLPN
                     FYIYEDIF"
     gene            complement(14669..16258)
                     /locus_tag="OE968_001643"
     CDS             complement(14669..16258)
                     /locus_tag="OE968_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
                     /protein_id="HCP7218925.1"
                     /translation="MKSIISDVINRFNATPFLFVGSGLTRRYYNLPNWEDLLKVFAEK
                     ISNDDFIYTSYKNKAKSENPKMGINPRIAELIENDFNKKWFSDSSIRSLDSKYLDIVK
                     SGVSPFKAEIAMYIKNNSKIVDKYQDEVEKLSNISKKSLSGFITTNYDCFLETIVDNY
                     TTYIGQENLVFSSIQGIAEIYKIHGCVSSPNSIVINEADYIDFDSKSAYLAAKLMTIF
                     VEFPIIFIGYSVTDVNIKKILNAIVNCLSNENAKKLEERFIFIEYEKNFNDIEISSHT
                     IVFDNKMITMTKIKLEDFNLLYEALSEKKSKLPVRILRMFKQEFYDFTITNKPTAKIR
                     VGSVDDTRIKDEDLVLAVGKASDFGLKGLKGLSFDEWYRDIVMNDLEFSSDELLEYAY
                     PSLIKQYNKLPLNKHLFNSTLEFPDYRTIALESDFENIISNSIKKNRNNTYIKNRSVY
                     GIWNDEHQSFEKATRLIAFLEEKEIDTEQLENLLKKIFEENPNILESAKTSEKTNLRR
                     LIRIYDYMKYSNMQKSLGYSE"
     gene            complement(16282..16845)
                     /locus_tag="OE968_001644"
     CDS             complement(16282..16845)
                     /locus_tag="OE968_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HCP7218926.1"
                     /translation="MSILSDRLKFLRKEKGVMQKEIANYLNITTSAYGFYEQGKRTPT
                     PEMLSSLAEYFGTTVDYLIGRYDNKASNISSKTSCNNTLFQKRLKELRAEKNMTQEDV
                     ANKLNLTKSAYGYYEQGKTVPDAYMLSSLAEIFNVTTDYLLGRSIVKNDIDTVAAHRV
                     NPHKDLPEEAQEQLNDYIEFLINKYKK"
     gene            16998..17219
                     /locus_tag="OE968_001645"
     CDS             16998..17219
                     /locus_tag="OE968_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCP7218927.1"
                     /translation="MNNLKELRTERNLKQKDVALKVGITTSYYGMIESGTRVPSLAIA
                     IKLSKCFGVSIEKIFLNTNTTRCCLKERS"
     gene            17222..18037
                     /locus_tag="OE968_001646"
     CDS             17222..18037
                     /locus_tag="OE968_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage regulatory protein/antirepressor Ant"
                     /protein_id="HCP7218928.1"
                     /translation="MKDLKIVKVNNKLTTDSRDIALMVEKEHKILLRDIRNYINQMEE
                     ANKNMSTDLYPSDYFIENTYLDDYKREKPCYAITKIGCDFIANKMTGIKGTAFTGIYT
                     KKFEEMEQVLKNEQPKLPTTYKEALQHLIEQVEVNEKLQLEGKMKDQVIKELKPKADY
                     TDMILKNKGLVTITQIAKDYGMSGKEMNKILHERGIQYKQSGQWLLYKQHQGKGYTHS
                     ETIDITRSDGMTDVKMTTKWTQKGRLFLYDLLKVNNILPDIEKEYSYQTSMLC"
     gene            complement(18216..18395)
                     /locus_tag="OE968_001647"
     CDS             complement(18216..18395)
                     /locus_tag="OE968_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Arc family DNA-binding protein"
                     /protein_id="HCP7218929.1"
                     /translation="MSTSLPKYTLRINRVLLEKIKYIAESEGRSANKEIEQIIKKHIE
                     DYEQRKGEIKINIEE"
     gene            18531..18710
                     /locus_tag="OE968_001648"
     CDS             18531..18710
                     /locus_tag="OE968_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218930.1"
                     /translation="MNSNKKRITVRMPEKLNEEITKKSKYLGLTKNSFILDILWKEFE
                     LLEYRSYKKEVDKHE"
     gene            18703..19494
                     /locus_tag="OE968_001649"
     CDS             18703..19494
                     /locus_tag="OE968_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ORF6N domain-containing protein"
                     /protein_id="HCP7218931.1"
                     /translation="MNNLQVIERNNERVLTTQQLADVYETDSRNISNNFNNNKDKFIE
                     GKHYFLLQGDDLKNFKGIHTEYENLKFASKMYLWTERGANRHCKILDTDKAWEQFDNL
                     EETYFKVKQHKPTCIEDVLIESLKEMKDLRLQVNQANSIALEAKTEVETIKDVVSLDS
                     NSWRTNTHQLIARIAKKQGGFEHINMLRTESYELLNKRFGVDLHRRLINKRRKMAEEG
                     VSESKREKVNNLDVIQDDKKLIEGYVAIVKDMALKYGISSDLSKN"
     gene            complement(19577..19771)
                     /locus_tag="OE968_001650"
     CDS             complement(19577..19771)
                     /locus_tag="OE968_001650"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218932.1"
                     /translation="MKFVYVKIFNNWIDITDIGSINGCNAIEYINENLDKMYSSNYVS
                     INYKDKNYCIHPSCIQIVTK"
     gene            complement(19927..20145)
                     /locus_tag="OE968_001651"
     CDS             complement(19927..20145)
                     /locus_tag="OE968_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCP7218933.1"
                     /translation="MTKFKDNIKLVRKQMNMTQKQFASLFGISERAYQYYEAGSREPN
                     LETLILISNKLNVSTDFLLGLSPNQNRN"
     gene            20258..20452
                     /locus_tag="OE968_001652"
     CDS             20258..20452
                     /locus_tag="OE968_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCP7218934.1"
                     /translation="MKINNNLKLQREKIGLTQLEVAQKAKITERSYQYYEAGERLPNI
                     RTALKIAIILNTNCEKLFNE"
     gene            20494..21288
                     /locus_tag="OE968_001653"
     CDS             20494..21288
                     /locus_tag="OE968_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor KilAC domain-containing
                     protein"
                     /protein_id="HCP7218935.1"
                     /translation="MNNLQLNNKNTITTLEIADMLEIRHWEVLRKLEGTEKTKGIIDI
                     LNDNNFVVVDYFIKSTYLDSKNESRPCYNVTKLGCDFLANKFTGEKGIIFTARYVRRF
                     NEMERVLKEQQPKLPTTYKEALQQLLVEVEEKEQLQLENQEKDKVIQLQQPKVLFADA
                     VSASNNSILVGELAKLIKQNGVDIGQNRLFTWMRENGYLIKRKGEDYNIPTQKSMNLR
                     IMEVKKRVINNPDGSTKVTRTVKITGKGQVYFVNKFKSSKQLSMLS"
     gene            21345..21554
                     /locus_tag="OE968_001654"
     CDS             21345..21554
                     /locus_tag="OE968_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218936.1"
                     /translation="MENKKIEEIEKRITMLENQLQAQLFSQITAQSNSDFIDYMYQCI
                     VLYLHEMNKSEKRKISEITKERIRK"
     gene            complement(21564..21938)
                     /locus_tag="OE968_001655"
     CDS             complement(21564..21938)
                     /locus_tag="OE968_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218937.1"
                     /translation="MQFSNNISKELQESIRKTVSDTSNTEYFYYAEFQYKIILKSIEE
                     FEKELDDEHEIALKLTNFGKDVLMIVEEVGYHNPCLIHYYGIVNGVYSEILQHTSQIN
                     FMITSVKKTDPSKPARRIGFIL"
     gene            22014..22211
                     /locus_tag="OE968_001656"
     CDS             22014..22211
                     /locus_tag="OE968_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCP7218938.1"
                     /translation="MLIGDNIKQILRKRDIKPYKLAKELNIDVSGLYKLLKNKNSNPT
                     IDTLIKLADYLDITLDELVGR"
     gene            22242..22634
                     /locus_tag="OE968_001657"
     CDS             22242..22634
                     /locus_tag="OE968_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCP7218939.1"
                     /translation="MDISESITKQFSDSLKSLIEIEINKQETDRVKSQTVEQKVKVLE
                     PKDIVVLIKRGYPNYLITVEEARGILKLDTVFMRRLVSTGLIKSLARGDGRKISRYEV
                     DDFIERNQGKNLDELLKVAERGDEIVKP"
     gene            22621..22764
                     /locus_tag="OE968_001658"
     CDS             22621..22764
                     /locus_tag="OE968_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218940.1"
                     /translation="MLSLNTNKNNIVTLKKDGKAIADIVFKDIKTGKKISVGVLNKKV
                     LVK"
     gene            22931..23173
                     /locus_tag="OE968_001659"
     CDS             22931..23173
                     /locus_tag="OE968_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218941.1"
                     /translation="MEAARLIAIGQIKQAEKEICKLQGTKNNSSLMWWEAVKFASQNI
                     LEGLEHDIELEASIEFREAMMYQEELEKDRPIDVQI"
     gene            23252..23533
                     /locus_tag="OE968_001660"
     CDS             23252..23533
                     /locus_tag="OE968_001660"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218942.1"
                     /translation="MKTKNEIIKGLEDRLFLLRFTTVDEVDWDVKFGQISALEFCIDK
                     HRKGCTLEQFKEHLDEYKLQGNYGDYIDGFVSVLERNIREMEGEIDGSE"
     gene            23520..24158
                     /locus_tag="OE968_001661"
     CDS             23520..24158
                     /locus_tag="OE968_001661"
                     /inference="COORDINATES: protein motif:HMM:NF016302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ERF family protein"
                     /protein_id="HCP7218943.1"
                     /translation="MEVNNIYIKLMDVRIKFNKLDIKKSGQNKFANFKYFELADFLPQ
                     ATELLQEAKLCPIVTFTNDYATLTLINGEKPTEEIIFTSPMRELQLKGSNELQALGGI
                     ETYQTRYLYIQLLNITENDTFDATSGKEDYKRNDLTNSSIKASENGQIKISQNQIKRL
                     FSIGNTIGKDSDRVKSEVYYKFNKEVKDLSKQEYDQICVGYEKLQREKGIIK"
     gene            24168..25063
                     /locus_tag="OE968_001662"
                     /pseudo
     CDS             24168..25063
                     /locus_tag="OE968_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894692.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
     gene            25083..25502
                     /gene="ssb"
                     /locus_tag="OE968_001663"
     CDS             25083..25502
                     /gene="ssb"
                     /locus_tag="OE968_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HCP7218944.1"
                     /translation="MNQVVLVGRLTRDPELKYIPGTGTAVASFTIAVDRNYINKEGKR
                     DTDFIPIEVIGKSAEYCANYITKGKLVALEGNIRVDNYQTQSGEKRIFTKVSTKSVQS
                     LESKNKSSNSYKESVQDGTIGLDPQGFEIIDDDELPF"
     gene            25532..25894
                     /locus_tag="OE968_001664"
     CDS             25532..25894
                     /locus_tag="OE968_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218945.1"
                     /translation="MFKVERYFSGSVVDNLIEDDLTCRNYLALYCCLLGITKNGKKIY
                     PKPEKMLAEFGVKKDRKIKKELPVRIRNVNTGEVKEFESIDGAACFLRLKYQAVYQAI
                     KKKTKTRSGWKVEYIKEE"
     gene            26128..26979
                     /locus_tag="OE968_001665"
     CDS             26128..26979
                     /locus_tag="OE968_001665"
                     /inference="COORDINATES: protein motif:HMM:NF012372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HCP7218946.1"
                     /translation="MNVLSLFDGISCGQVAFERARIKVENYFASEIKEIAIKVAMNNY
                     PKTIQLGDVRELNVSKIPKVDILIGGSPCQNLSKGRLIANKIQDGLTGDKSNLFWEYI
                     RILKQLNPEYFLLENVVMPKKDENMISQLLGVEPIKINSNLVSYQNRDRLYWTNILNV
                     QQPKDLKISFQDYKDTSFDYCKEFEIKKTPSREKMWGNGLNGNCKNVTYEDKINCVTL
                     KQDRFSNSGLVEFGSFCRYLTTRELELAQTLPVGYTKGLSIRQAQNVIGDGWTIDVIA
                     HILSNIN"
     gene            27296..27493
                     /locus_tag="OE968_001666"
     CDS             27296..27493
                     /locus_tag="OE968_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218947.1"
                     /translation="MNKFQKAVSQMVKQEEKENLLQGYENCIVGRSISSSIRRYVKGF
                     EKFGYSVHEVYEFINDINKYE"
     gene            27520..27936
                     /locus_tag="OE968_001667"
     CDS             27520..27936
                     /locus_tag="OE968_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003366126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1064 domain-containing protein"
                     /protein_id="HCP7218948.1"
                     /translation="MSKYNNKKIVIDGIKFDSKDESEYYLYLKEKKENGEIKDFGLQQ
                     KFELQPKFKKDGKSYRAITYTIDFAIYKWNGEVVYIDVKGYSTQQGELRKKLFDYKYQ
                     DKKLIWIAKSKKYGVDGWIEYSELKKKRKENKKKVA"
     gene            27955..28455
                     /locus_tag="OE968_001668"
     CDS             27955..28455
                     /locus_tag="OE968_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218949.1"
                     /translation="MASKVKKEFFMATKKHLENYKQLHINIESLKLQIKNLKEFHLGD
                     FMQGLSYDSIPISKTNSISNQVENELINLEEKIIEKQIELYEMEALKYTIDVSISNLK
                     PIHKQIIRYRYIEGLEWSLIVDKVYLEERQLRERANQAISSISIALFGKKALIEQEPL
                     FKMLDL"
     gene            28877..29083
                     /locus_tag="OE968_001669"
     CDS             28877..29083
                     /locus_tag="OE968_001669"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218950.1"
                     /translation="MNRFEGIYSFAEATKLWDLKDSTLRKAVATGKLVENIDCKKFGR
                     DWVVTIEAMEREYGKLNNIMKDLD"
     gene            29572..30759
                     /locus_tag="OE968_001670"
     CDS             29572..30759
                     /locus_tag="OE968_001670"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218951.1"
                     /translation="MLNEKNLKNIKNILQMVQMKHLKDFENWGINKRKKETAINSLIN
                     IIQNDGEKLDYFKEWISIFTIDGHNNYYVFNYNDSDLELEDLKNIVEDIVSENLLEID
                     TSDLEETKVIYKKNDVINKRLIIRFISPALISCKNENENGNIESGLEKTFYFATLFLD
                     LSLKQIIVSIPHTVGIKSIDNIEAKARDFSEIAKYYVSKLEDLLTTYNIQIEKYNDWI
                     YDATYELAEEGSAHNNPEINKKYEENIDKIDEFAKKIAIASGITDKAIIENFKEGVGI
                     LYENILIDEFGVVEDENQYSTFVQNGDGVNSYCRVGSKTATLKSGKGHAIAKTSRNNE
                     DVKNLGVMKSFNGTLSRFLIEVLDKELYLIRTDTSKFIEERVIYDVIRKVGEYKYTFR
                     KSE"
     gene            30704..31090
                     /locus_tag="OE968_001671"
     CDS             30704..31090
                     /locus_tag="OE968_001671"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218952.1"
                     /translation="MMLYEKLENISILLGNQSKAKSIIEELEKLMKSDIITPRLLARK
                     TKVTLLEATRVLEFLVKENELEFFIVVECSNPDSVYENEIGHYKYFTSIKEFNAFSKG
                     QECPICGCGYKYNFEDTKIGFRRLEK"
     gene            31095..31865
                     /locus_tag="OE968_001672"
     CDS             31095..31865
                     /locus_tag="OE968_001672"
                     /inference="COORDINATES: protein motif:HMM:NF016362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HCP7218953.1"
                     /translation="MSLDTLKEYLSICDDNLIWEPFYDDSMLLDEFSNYIKEIELSKE
                     WNKSKNHEKGKILEQLVRFIMSRFTILSDISVNKSTTDNELDVFVKFNDNIPIPFLCN
                     IKSKIVCECKNWKSRKVDVGMVSKLAEICNKNNAGLGIFISLNGLTGKGWQYAEGKRR
                     KLYLSDKMPIISFTVDEITKLKYKRYNLLTMIKCKMQALIDEMEFAGGELRLLESELG
                     FIDCLNENIESLKMLGLITEVEYNNIKVRINHRYDIVN"
     gene            31923..32606
                     /locus_tag="OE968_001673"
     CDS             31923..32606
                     /locus_tag="OE968_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCP7218954.1"
                     /translation="MQDVKEKVKQDYLKGMKQKEISAKYDISLNTLKSWIKRYNWANE
                     KKKGAPKNKRGAPIGNKNATGPPGNKNAEKFGFFSKYLPEETQDLINEIKDKDKFDIL
                     WEQITIQYAAIIRAQKIMYVKDKEEMIKELKKYESTENGEKIEYEFQFAWDRQASFLN
                     AQSRAMSELRSLIKQYDEMIHKDWNLATEEQKTRVEKLKCEVDNLSKDDIGDDELKIS
                     VDYGDRNDS"
BASE COUNT        13314 a         3427 c         5570 g        10325 t
ORIGIN      
        1 taaaaaatat gaatgaaagt agtgggtttt ataaaaaaac atatttagat tttaacatct
       61 aaaaggagtt ttcaaagcta atatttcatt tttaaataaa aaaataaaat attagttttg
      121 atttctggtt taaattgggt tataataaat tgtcaaatta tttattaata taaaatagac
      181 tataaaacaa gcaaaaatca tactattata taaaagacct taaagataga aaactacaga
      241 aagaagccaa aatgtttttg aaaaaaatga aattttattg caaaaaaatc aaaatgaatt
      301 taacttaata gttataatct atttttagtg ttacaaatat acaatgtata ttatacaata
      361 taaaaaatac atttacttag aagtattatt atatttggat ttttggtttt tataattttt
      421 ttatatttaa acatagctaa aaataaaaga ttacgaaagc taagtagagt ttattttatt
      481 ttaataaata ataaagctat ttttctatat attggcataa tatatgctta tttaactatg
      541 aaattaaaat taaataggat taatgaggag gaaaaaaatg ggaagtaatg aactgaaaaa
      601 gactcttggc gtatcagcag cattatcaac tgttgttggt tccgttatag gagcgggcgt
      661 attttttaaa ccacaagcag tctatacatt aactggagga gctccaggtc ttggtatatt
      721 ggcatggtta atagctggaa tcataactat aacagctggt cttacagctg cagaggtatc
      781 agttgcgata ccaaaaactg gtggaatgat ggtatatata aaagaaattt atggagaaaa
      841 attaggtttt ttaactggat ggatgcaaat tgtattattt tatccaggga tgatggcagc
      901 attaggtgtt atatttggag aacaagcatc agcactaatt ggtagtccat cacttttact
      961 tccaatagca attggaatta tagtaatagt tgcagggctt aatatgttag gttcaaaaac
     1021 tggaggagtc atacaaactg tttctacaat ttgtaagtta ataccactta ttttaataat
     1081 ggttgttgga tttattaaag gtggtggaaa taatccaata cttacaccta tggttggtga
     1141 aggattaagc ctgggtagtg tactaggtca agttttaatt gctatattat ttgcttttga
     1201 tggatggatg aatgttggta ctttagctgg agaaatgaag aatcctggaa aagaccttcc
     1261 aaaagctata ataggtggat tgtcagttgt tatggctgtt tattttataa taaatttagc
     1321 gtatctttgg gtattaccag ctaatgaatt agcaaattat gcttctcctg catcagcagt
     1381 tgctgaagtt atatttggtt caatgggtgg aaaaataata tctgtaggta tattaatttc
     1441 agtgtttgga gcattaaatg gatttttact aactggttca agggtggcat atactttagc
     1501 tacagataag actttaccaa agtatggtat attttctaaa ttaaattctg ctcaagttcc
     1561 agcaaatgca atagcattag tatctgttat tgcatctata tatgctttgt caggtcaatt
     1621 taatttatta actgacttag ctgtatttgc tacttggata ttctatgtat taacttttat
     1681 aggggttatg aaacttagaa agactcatcc aaatatacca agagagtata aagttccatt
     1741 atatcctatt gttcctataa tagctatagc aagtggtata tttgttgtag ttaatcaatt
     1801 gtgttttgca ggtatgaaaa ctactatgat atctatagga ggtcttgtaa taacagctat
     1861 aggcttacca gtgtatgctt atatgactag aggagtaaaa agataaacca agtagtttac
     1921 aaatgcttca taattaaaat aaaagagact gtctcaaata gagataagtc tcttttttat
     1981 tgttaaaatg gtaaagatat gtttaatttt acaaaaaaag agcgttccat gaactaaaaa
     2041 gtttatttta aggtattcat tttattttta gttttttgat tataaaatta aacatctaaa
     2101 aaattattta ttttaaaata ctttatttta aagtgttttt tatcaaacta agtggtatct
     2161 gtacaacaaa tattatacat agcttttatg aaaattaaat ctttctgtta tatataatag
     2221 aatattgtat tatatagaaa atattacctg attaatatag tgatttataa atgagattag
     2281 aaaattttat ttgataacaa aaattagata atatgaatat ataatgtatg tattaaaaat
     2341 gtggcaaata gttgttttgc tatttattat ttgtttaata tttctaattt ataaaaaaaa
     2401 aattataaat tttaaaaatt ataaatgaca ttttaactag aattaattgt aaaaaacact
     2461 atataatact caattttcaa cattctatac aattatacag aaattataca gcataataat
     2521 caccgaaata acaaatttta aaaattaagc aaaacttttt gtcgaagttc aacgtctata
     2581 tatatgtagt gtaaattttt gggataaaat actacaaaaa tataaatgta aaaatatagt
     2641 aatattggag gtcgaacgat gagaaataaa aagaaaaaaa taaatagaaa gaagttgtat
     2701 ttgcttttaa gtgctattgt agtgtgtctg gcttttatag tagttggtgt tcgcgtcagc
     2761 tctttaaata tgaaggaaaa tgaaattagt agaaatgcaa aactgtcaag ttctactatt
     2821 acagatatag tatctaatac atcaatagaa gttagtaaag ggccaagtaa aagttctgga
     2881 aaaatagcat acataactat agatgatggt ccatctaaat ttactgacga gatgataaaa
     2941 actttaaata aatacaatgt taaagcaact ttttttatga tagatgggaa tatgaaggaa
     3001 tatccacagc aagttaaaaa tataattaaa aatgggaaca cagcaggttt tcatagtgta
     3061 tcacatgata ttcacaagct ttatgttact agtacatcag caaaagagga atttgataca
     3121 aatgatcaaa ctttttataa gataactggt aaacattcaa aagtaataag aataccttat
     3181 ggaagcaaac catatacacc acaagcctct tatcaggctt tagttgatgc tggatataaa
     3241 atttgggact gggacttaga tacagaagac tggagatcta attcttctca aattgtacaa
     3301 aatgtaaaaa atcatattaa gaatagaaaa ggtgaagata aagaccaact tgtagtttta
     3361 atgcatgaga aaaaacagag tgcagaagct ttagattcag ttttaaaatt cttatcagat
     3421 gaaggttatg aatttgcgcc agtagatcaa aaccaaatac caaaaaatta ttggttacgt
     3481 aatttagagt agttaaaata taagaatatt gattgatatt tttagaaatt gagaataaaa
     3541 atgagtgagg tgtaggtata ttgaataaaa aactttatat aggaatggtc ggaatattgt
     3601 ctttgatgat ggttggttgt aataaaagtt tagcaaaagt aaatgatgtg gaaatcacaa
     3661 aagaacagta caaaaaaaca aaagcagttt tatctgctac taataattat ataaatgggc
     3721 agtctttaga tgaattagaa aaaactttgg ataaaaaagg tagaaataaa ttagaaaatg
     3781 ttataatatc gtttatggtg gataatgaac ttttatatca agaggctaag gataaaggac
     3841 taactccaag taaaagtgaa gtagactcaa aatatcaaga actagaagat aagatgaatt
     3901 tgaatacaag ctataaggaa aaaatggaca aagcaggtgt tgataaagat tatttaaaac
     3961 aagaaatatc tagagattta gcaatagata aaaataaaaa ggcctttgaa gatagaataa
     4021 acataagtga taatgatatg gaagcctact atacaagtca taaaaaagat tttaatgtag
     4081 aagaagtaag tgcttctcag atacttatat cgactttaga taaaaataaa aaagaagtaa
     4141 gcaaagataa aaaagaagct ttgaagaaga aggcagataa tatattgact aaaatcaaaa
     4201 atggagaaag ttttgaaagt ttggctaaaa aatattcgga tgataaagca actggaaaaa
     4261 atggaggaca gctaggatat tttacaaagg atgataaaaa tgctgagttt acaaaggaag
     4321 tgttcaaatt aaagaaaaat gaagtttcaa atgtgtttga aactagttat ggatatcata
     4381 tagtcaaagt tactgataaa agagaaagac aaaaaagttt taatgagtgt cagagtttaa
     4441 taagagaatc tattttaaat gaaaagtata ttgagcatat aaaaaaactg aatgaagatg
     4501 ctaaaataga cagatagaat ttctaacagc tcaatcctag cctgtaatcg gagggagatt
     4561 ttacaggaat gtttaagagt ttaaagagaa cgaaagttga gaaatacatt atcgataata
     4621 aagactcttt ttatagaata gcatatagtt atacgaagaa tgaagaagat gccttagatg
     4681 tggttcaaga agccatgtat aaggcactat actcagtgga aaatattaaa gaagtaaatt
     4741 atataaagac atggttttat aaaattttag ttagaacgag tatagatttt attagaaaaa
     4801 accgtaaata taataatatg acagatattg accttataga tgagactgga gagtatgata
     4861 aatatactga tttggattta agaagagctt tggaagaatt acctattgaa tacaaatcta
     4921 ttataatatt aagatttttt gaagatttaa agattgaaga agtagcaata atattggatg
     4981 aaaatgtgaa tactgttaaa actaggttat atactgcttt aaaaaaacta aaattaaaaa
     5041 ttgaagagta gggataaaaa gaatgacaag caaagaaagg ttaaataagt taaaagatga
     5101 gtatcataaa attccaatac ccaagaaatt agatactata ataaatcatg aaaaaataga
     5161 aaacatatat cgagagaaaa ataaaaaagt aaatagatta agatttaaag ttgcaatagc
     5221 ctttgcatgt atatttacag tattagtaaa tataagtcct gtatttgcag acaatttttc
     5281 taagatacct gtaattggag caatagtaga agtaataact ataaaaaatt atagtttaaa
     5341 aagtgaaaat tatgaagctg agattgatat tcctaaaata cgaggtttaa aagataaaaa
     5401 cttagaacaa agattaaaca gtagttttat ggaagatgga aaaaggcttt atcatcaatt
     5461 ccaagagaga atggagaaga tacaatcatc aaagaataaa ggatataaat ctttaagttt
     5521 gagttatagt gtaaaaaata attctaaaaa atttctatca atagagatga caaaaaatga
     5581 gatagaggct tcatcatatg tgagtaaggt acattatact attgataaaa aaagacaaat
     5641 agttttgact ttgccaatgc tttttaaaga tgataagtat ataaaagtta taagtgataa
     5701 tataaaagaa caaatgagag aacaaatgaa aaaggatagt acaaaatcct attttataga
     5761 tcaaaaaaaa gacttgcctg ttgaagattt taaaacaatt aataagtatc aggattttta
     5821 ttttaataaa aatgaagacc ttgtaatttg ttttgatgaa tatgaagtag cacctggtta
     5881 tatgggcgca gttgagtttg taataccata taaagtaata aaagatttgt aaattgaata
     5941 gtagtttata tataaatctt ttaaggagga caatatgact acatataaaa aacttaaaaa
     6001 atctatattt aaaattgcta tattttcaat atgcttatta gtttcattag tagatacaaa
     6061 ccctatattt gcaggtagtt cctttaatga aacttcaaat agtgatacga taaaggtgtt
     6121 aaatgctaag agtatcaact ttaaacaaga caattatgaa gtgaatgtga gtattcctaa
     6181 aataaaaggt ttaaaagata aaactttaga gaataaatta aacaatgagt ttttgcaaga
     6241 tgggaaaaaa atttacagtg aatttcaaaa taaaatgaaa aaggaaaata ataagggtca
     6301 tagataccta aatgtaatcc ataatgtcaa aaataattct aaggactttt tatcaataga
     6361 aatgacaaaa gaagagatag aagcttcctc atctataact aagaagcatt acactgttga
     6421 taaaaataga ggaatactat taaatttacc aatatttttt aaagatagta gatatattag
     6481 agctataagt gataatataa aagagcagat gagaaatcaa attaagaaag atgatacaaa
     6541 atcttatttt atagaccaag ataaagactc gccagtgaaa gattttgaat ctataaataa
     6601 gtatcaagat ttttatttta ataaaaatgg aaatcttgtg attagttttg atgaatatga
     6661 agtagctcct ggttatatgg gagcagtaga atttgtgata ccaaataaag taataaaaag
     6721 actaagatag atatatagaa gatttttaga tagactggta aggagaatta tatgaatata
     6781 tatgaacaag caataagatt aatagaaaat aatgaggatt tcgcatttgc tacaataacg
     6841 tctcattcag gttcaacacc acgtgaaact ggagcaatga tgattgtgaa aaatgattct
     6901 actatatttg gctcagtagg aggaggtagt gtagaagcag aatgtataaa acatgcaatt
     6961 aatgttataa aaaacagaga atcaatgttg tataaattta ctctaaacaa atctgatgtg
     7021 gcaaaactag gaatgatatg tggaggtact ggagaaatac aaatagattt tatagatagt
     7081 aaattaaaaa gtaatataga aaaatttaat aagagactaa aggaaaatac aagtaaagca
     7141 tatatatttg gtgcaggtca tatttcaaga gatgttgctg tgatactatc tcttttagaa
     7201 tttagaacag tagtaataga tgatagagaa gaatttgcta atcatgaaag gtttccagaa
     7261 tcagaagtag tagttttaga ttcttttgaa aacataccag attttcccac tgacgaaaat
     7321 agttatataa ttattttaac aagaggtcat ctatatgatt caagtgcttt agaatgggct
     7381 cttaaaagag aggctggtta tataggtatg attggaagta gaacaaaaat tggattgact
     7441 tatgaaaaac tcatgaaaaa aggttttaag aaggaagaat tatcaaaagt acatgcacca
     7501 ataggcataa aattgaatgc tcaaacacca gctgaaatag ctgtatgtat agctgctgaa
     7561 cttataaatt gtagagctaa taaggaaaaa taaactaatg aacacaggga gtaaagatat
     7621 tgatacttta aaggttaatt ttagagggat tgaaataaaa gcagttttag tatataaaaa
     7681 tagaaaaaat atttctataa aaatagatcc atttggcaaa ataactgtaa tgagtcctcc
     7741 taaaatatcc aaaaaaataa taaaagatat aattattgaa aaaggagact ggatacttaa
     7801 aaagtcagaa aaatgtaaag gaagagagga agtatataaa caaagaatgt ttataactgg
     7861 cgaaaaattt ctttatttag gtgaagagta ccatctagtt ataaaagaac tgttgagaga
     7921 ttctgtcaaa aaaagtaact gtagaataac tattaacgaa tatcaaatag ttgttcagac
     7981 aaatgataca agtacagatt ttattaaaaa atctttaaaa tcttggtata agatggaaag
     8041 tgaaagaata gtattagaga gaatagattt tcttaaatta aattgtgaaa taatgaagca
     8101 attagttcca gcgagtgtta aggtaaaaga acaaaataag agatggggaa gttgtacagc
     8161 tcaaaaaaat atttatataa actcaaaaat atctatggca agattagatg taattgatta
     8221 tgtaataata catgagttta gccatttagc acatatgaat cactctaaaa aattctatga
     8281 tttagtaaaa tccattatgc ccgattataa agataaagaa aattggctaa aaataaatgg
     8341 atataaaata ataatctgaa aacgattatt ccaaaatata ggcgtaaagt ataaaagaag
     8401 tattattgtg aaaaaaataa ataatctgaa aattttaaaa aaagtcattg acattgtaaa
     8461 tgatagagaa tataatctat attaacaaca aaacagaatt gaaatataaa attaaaaaat
     8521 taaaagcaat gacagagaca acaatactaa tagtgttatc cacagagaac caatgttgct
     8581 gagaattggt gttaacagta gtataatgat cactctggag cttttgtact gaatattttt
     8641 agtaagtaca aacgtatgtc aacgttacat gactaaggtt aaggtaatta attacccgac
     8701 ctgaaaaaag aggggtagat gtatttttta tatctacaaa taaggtggta ccgcggaata
     8761 taactttcgt ccttataagt aatatttata ttgcttataa agatgaaagt ttttttattt
     8821 taagtgatat aaataaattt aatccatata aaattaataa aaaaataata aaaataagga
     8881 gggattttta tggaaaatac tgtatatgct aaattaaacc aaggaataga ttctttttta
     8941 agagtggcta tgactctaag aagaagagag gttgatatac aatcaataag tatgactgta
     9001 gataatatga ataattcagg tataaaatta atagtaaatg aagaaaagac atccttagat
     9061 tctgtcttaa accatatgaa aaaactacat gatataagag agataactgt tgaaagaatg
     9121 agacattaat taaatatatt ttataaaact aaagataaat atgcttattt taaaataaaa
     9181 aactaaagat aaatattaaa taagaaaaat cttagattaa aatataagtg tcattgaatt
     9241 tattagttta tcacagttaa taaatttatt agtttgttgt agctaataaa aactgaaaat
     9301 tctaaaatta taattgtaag attatataaa tttagaattt aaatctgttg aataatatta
     9361 aaacaatgat aatgagtatg aatttctaat aaaaataaat atcataaaaa taagaaaaag
     9421 tattgggagg aaatgaaaat ggcaagaatg tattatgaaa aagatgtgga tttagaggtt
     9481 ttaaaaaata aaaaggttgc agttttaggt tatggaagtc aaggacatgc acatgcacaa
     9541 aatcttagag ataacggtgt acatgtagtg ataggtcttt atgacggaag taaatcagca
     9601 caaaaagcaa aagaagatgg atttgaagtt aagagtgtag cagaagctac aaaagaaagt
     9661 gatttgacaa tgatgttaat gcctgatgaa aagcaaaaga aagtttatga agagagtgta
     9721 aaggataact taaaagaagg tcagacatta gcttttgctc atggattcaa tatacattat
     9781 aatcaagtac aaccaccaga atttgttgat gttgtaatgg tagctcctaa aggacctggt
     9841 cacttagtta gaaatgtatt tacaaaggga agtggagttc ctgcactatt tgcagtatat
     9901 caagactaca ctaaaaaagc tacagagaca gttttagcat atgcaaaagg gataggagca
     9961 acaagagcag gtgttttaga aactactttt aaagaagaaa cagaaacaga tttatttgga
    10021 gaacaatcag tactttgtgg tggaataagt gaacttataa aattgggata taaaacgctt
    10081 gtagatgcag gttatcaaaa agaagtagca tattttgaat gtttacatga aatgaaacta
    10141 atagtcgacc ttatatatga aggtggattt gaaagaatga gatatagcat aagtgacaca
    10201 gcagaatatg gagattatgt atctggtaaa agggtaataa ctgatgctgc aaaacaaggt
    10261 atgcaaaatg ttttagagga tatacaaaat ggaaaatttg caaaagcgtg gattaaagaa
    10321 aatgaagaag gacgtgaaaa cttcctaaaa actagagaag aagaatataa tacagaaatt
    10381 gccgaagttg gtagaaatct aagaagtatg atgtcattct taaaataaat atatattaaa
    10441 tggattagtt tgagggaaag agtggtgtat agtagtgcgt atgagtggag caaaggtaat
    10501 tttagaatgt ttaaagaaag agggaattga cacaatattt ggatatcctg gtggagccgt
    10561 gatacctctt tatgatgctc tatacgatta ttcagatgat tttaaacata taaggacatc
    10621 ccatgaacaa ggtttagttc atgctgcaga tgggtacgca agaagtacta atacagtagg
    10681 agtttgtttt acaacatctg gtccaggagc aacaaatgcc ataactggaa tagcaacagc
    10741 ttttatggat tcttcaccta tggttgtaat ttcagggcag gtgccaacta gtttattagg
    10801 aaaagattct tttcaagaaa ttgacataac tggagcaaca ttatctatga caaaacataa
    10861 ttatttagtt agaaacacta aagaattagt tcctacaata aaagaagctt ttagagttgc
    10921 aaattcaggt agaaaaggac ctgtacttgt agatgttcca aaagatttat ttttagcaga
    10981 aatggatttt agtggtgagg actatgattt atgtcaaata gatgattata tggattataa
    11041 gagtgatttt gatctagatg atgaaactaa tattaagctt ttaaatgaag caatagatat
    11101 cataaaagaa tctaaaaagc ctataatata tgcaggtgga ggtgttaaat cttcagacag
    11161 tgaggaaatt cttgaaaaat ttgcaactaa gatagataca cccgtactaa atacacttat
    11221 ggggcttgga aatatagata gaaagaatga attatctctt ggaatggttg gaatgcatgg
    11281 aagtagagaa agtaatttag cactttctaa ttcagattta gtaatagcga taggtgcgag
    11341 atttagtgat agagtgataa gtaaaagttc tgaatttgct aaaaatgcaa aaataataca
    11401 catagacata gacccatctg aaataagtaa aaatatagaa tctaatgtat ctttggttgg
    11461 agatgtaaag ctagtcctta gtttattaat tgaaagggtt gaaagtaaga ataatagcaa
    11521 ttggaaagaa gagataaaga gatttagaaa gagtgagggt gtacaaacat atgaatttca
    11581 tccacaaaat atactaaaaa aaataaatga aaaatatgaa acattaaaga aacccactgt
    11641 ggtagtaact gatgtcggtc aacatcaaat gtgggctgct aagtactgga attttaaagg
    11701 taataaaagt tttataacat cagcagggtt aggaactatg ggatttggtt taggtgcagc
    11761 tattggaact aaagttggta atgtagataa aaatgtagtt ttagtcactg gtgatggaag
    11821 ttttagaatg aactgtaatg aactagctac agttgcaaat tataatgtac ctatgcttat
    11881 tttattactc aataatagaa cattaggaat ggtaaggcaa tggcaaaagt tattttccaa
    11941 tcaaagatac tctcaaactg acattaatga aaatgtggat tatgttaaac tcgtaaatgc
    12001 atataatatt gatggatata aggtatccag tatggaagaa ttaggaaagg cgctagatat
    12061 gatagatttt aataaacctg tatttttgca atgtgatata gataaggatt atgatgttta
    12121 tcctattgta gcacctaatg atgcattgga aaatttgata tgtaactaaa acttatactg
    12181 aatattgata aaatttttta ttaaattttt attggtattc agtttttgtt gtttagagat
    12241 agattggcat tttttatttt tgcaaataaa tcaatgacta tataattaag aacttattaa
    12301 attttaatta tacaatttag aatagtatta caacttaagt aaatattaag ttttatttgt
    12361 tagatttatt attaatacct tatattagtt atggttgtta tatactctaa agccttgaaa
    12421 ttacaagtat atagatgatt atataaattt gataatttta gcttttaaaa tagataaatt
    12481 agattttgcc acccatttgc caccgtatta tatttttggg tggcaaactc taatttgtaa
    12541 ttttttcaaa tatatctaca gtttcatttt tcattttatc agttacatgt gaataggtat
    12601 ccattgtagt tgatagttgg ctatggccca aacggttttg tatgtcttta atgttagcac
    12661 cattttctaa taatagagta gcatgtgcat gtcttaaaga atgaaaatgg aagtcattgt
    12721 ttaaagctac tcgaatttgt cttactatag tgtctaaagt gtgagtattc acttgttgac
    12781 cattttcttt ggtacatacc cagtcactat caaagtaaaa ttctccatat tttaatttca
    12841 ttttcttttg atataattta tgttctttta atgcctttat taaagtgtca cctgtaaata
    12901 tagttctgca agagctttct gtttttggtt gccctaattc aaacattcca tttggttttt
    12961 taatcaaagt atgtcttact gtgatagttt tattatcaag gtctatatta tcccatttta
    13021 gtgcaataat ttcacctctt cgcataccag tatgaaatcc aattagtaaa actatacgtt
    13081 gaaatgaatc ttgaggaaat atatttagta tttgattaaa ttcttctaat gtaatagttt
    13141 taattttatt agtttctgtt ttagatttag tttttggtat gctcacatat tgcatagggt
    13201 tttctcgtat atgtttgtaa ggatggactg ctgattttaa tgacctatgt aatatggctt
    13261 ttaatacttg taatgtattt tgagagtaat cctctttgta ctttctgttt atgaagtttt
    13321 gtagtattgc aggagttaaa gcttttactt tgtaagctcc tagttttggc tttatatgtt
    13381 tttctatgtt tattcggtag ctttcttgag tgttgtattt acagttaagt aagacatatt
    13441 ctttgtacca aaagtctaag tagtctgata aactgatatt gctttcttca aatactatgc
    13501 cagagttttc atattcattt agtgcttctc ttaaggcttt ttctgcttct tttttagtat
    13561 tgcctccaac tctttctact ttttttcttt ttccttctac tatgcctagg tcaaagtagt
    13621 aataccattt gttacttctt tttcttactc cacctttcat aatagtatcc ctccctttta
    13681 gaatgtatgt ttgtttggtg tttatataaa agagcagatt aactgctctt tatatacttt
    13741 tgttatgtac aatattatct taattttgtt tatttggttt ttacttaatt attttcttaa
    13801 tattcttaca attttttagc ttttatgtgt agtttattat aataatattg aaatatatat
    13861 ttattaagta aaaaatctat aaaagtagaa taaatgagtt taaaaaatat cctcatatat
    13921 gtagaaattt ggcaaattag ttaatactaa aaatctatta tttcctaagt ccaacatgct
    13981 tttctttttt gatagaaatt ctaatctttt tagtaagaag ttgatgctaa cttgtaattc
    14041 ttcagctatt tcgtatacac ttgtagcgtg tgaattaata acatgtatta tttcttcttc
    14101 tgttataaga aattcacatg cccattttag tgctttgttt tcagttttgt ctatcaagat
    14161 tttatttttg taactgtttt ttgaagatac atagtttcca acactggtaa aatgatgtcc
    14221 taattcttct gctaagattt ctattagttt agcattgttt tgttttaatg aattaagtaa
    14281 tgatataatt tttagtcctt gtctgtttat atacaatcct tttatgtcat ctgctatttt
    14341 gtcagtgtag taaatttcta tctcttcatt atttgctaag tctaaaagtg cgtctagttt
    14401 gttcattgaa atccccctat aaaaagaatg tatttttgat ttttgttata tataaagagc
    14461 aggtgtgaac tgctctaaat attcattttt tatccaaaaa agattggata attttagctg
    14521 tagacaaaat atggattata gtatatgatt ataatataat tacatataat atatgtaagc
    14581 acttacaaat gtgtgttagt atagttagca ctaaatttgt atttgtgctt aaagcgatta
    14641 aaggagtttt ggagcggtgg gtagagtttt actcactata accaagactc ttttgcatat
    14701 tagagtattt catgtagtca tatattctaa taagccttct taaatttgtt ttttcgcttg
    14761 tttttgcaga ctctaaaata ttaggatttt cctcaaatat tttcttaagt agattttcta
    14821 actgttcagt gtcaatttct ttttcttcta aaaaagcaat aagtcttgta gctttttcaa
    14881 atgattgatg ttcatcattc caaataccat aaacacttct attttttatg taagtattat
    14941 ttctattttt tttaatacta ttgctaataa tattttcaaa gtcactttct agtgcaattg
    15001 tcctataatc tggaaattca agtgtgctat taaaaagatg tttatttaat ggtaatttat
    15061 tatattgctt aattaaagat ggataagcat attcaagtaa ttcatctgat gaaaattcta
    15121 agtcattcat gactatatca cgataccatt catcaaaact taatcctttt aatcctttaa
    15181 gaccaaaatc acttgccttg ccaactgcta aaactaaatc ttcatctttt attcttgtat
    15241 catcaacact accaacccga attttagcag taggtttgtt agtaattgtg aaatcgtaaa
    15301 attcttgttt gaacattctt aatattctaa ctggtaattt tgattttttt tcagataatg
    15361 cctcatagag taaattaaaa tcctccagtt taattttagt catagtaatc attttattat
    15421 caaaaacaat tgtatgactt gatatttcta tatcattaaa gtttttttca tactcaatga
    15481 atatgaaacg ttcctcgagt tttttagcat tttcattaga tagacaatta actatagcat
    15541 taagtatttt ttttatattt acatctgtaa cagagtaacc aataaatatg ataggaaact
    15601 caacaaatat agtcattagc ttagctgcca agtaggcact tttgctgtca aagtctatat
    15661 aatcagcttc atttattaca atactatttg gagaagaaac acatccatga attttataaa
    15721 tttctgcaat accttgtata gatgaaaaaa ctaaattttc ttgacctata tatgttgtat
    15781 aattatcaac gatagtttcc aaaaaacaat cataatttgt tgtaataaat cctgataaac
    15841 tttttttaga gatattacta agtttttcaa cttcatcttg atatttatct actattttag
    15901 aattattttt aatatacata gcaatttctg ccttaaatgg agaaactcct gatttaacaa
    15961 tatctaaata cttagagtct aagcttcgta tagaagaatc tgaaaaccat tttttattaa
    16021 aatcattttc aataagttct gcaattctag gatttatacc catttttggg ttctctgatt
    16081 ttgctttatt tttataactt gtatatataa agtcatcatt actaattttt tctgcaaaga
    16141 cttttagtaa atcctcccaa tttggaagat tatagtatct tctagttaaa ccagaaccaa
    16201 caaataaaaa tggtgtagca ttaaatcggt ttatgacatc tgatattata gatttcatat
    16261 aatttatcac ctacttttaa tttatttttt atacttattt attaaaaatt caatataatc
    16321 attgagttgt tcttgagctt cctctggtaa atctttgtga ggattaactc tatgtgcagc
    16381 tacagtgtct atatcatttt ttacaataga cctacctaat aaataatcag tagtcacatt
    16441 aaatatttca gcaaggctag atagcatata agcatcagga actgtctttc cttgttcata
    16501 ataaccataa gcgcttttgg ttaagtttaa tttatttgca acatcttctt gagtcatatt
    16561 tttttcagct ctaagttctt ttagtctttt ttgaaataat gtattattac aagaagtttt
    16621 gctagaaata ttgcttgctt tattatcata cctacctatt aaataatcaa cagtagtgcc
    16681 aaaatattca gctaaactag ataacatttc tggggtaggt gttcttttac cttgttcata
    16741 aaatccatat gcactagtag ttatgttaag atagttggca atttcttttt gcattacacc
    16801 tttttctttc ctaagaaatt tcaatctatc tgataaaatg ctcatataat cactcctctt
    16861 aataaagttg cctttattaa ataatacaac aaatagttgt aaaatgaaat aaaaaaataa
    16921 aaaaactatt tacaaacaac atatagttgt gtattatata agtataaaca acaaaatgtt
    16981 ggtaaggagg atatagcttg aacaatctaa aggaacttag gacagaaagg aatttaaagc
    17041 aaaaagatgt tgcattaaaa gtaggtataa ctactagtta ttatggaatg attgaaagtg
    17101 gaacaagagt accaagttta gcaatagcaa taaaattatc taaatgtttt ggagtatcaa
    17161 tagaaaaaat ttttttaaat acaaatacaa caagatgttg tttaaaagag aggagttaaa
    17221 tatgaaagat ttaaaaatag taaaagttaa taataaacta acaactgaca gtagagatat
    17281 agctctaatg gttgaaaaag aacacaagat tttactaagg gatataagaa attatataaa
    17341 ccaaatggaa gaagccaata aaaacatgag tacagatttg tacccatctg attattttat
    17401 tgaaaatact tatttagatg attataaaag agagaagcca tgctatgcaa taacaaagat
    17461 aggttgtgac ttcatagcaa ataaaatgac aggcataaaa ggtacggcat ttacaggaat
    17521 atatacaaaa aaatttgaag aaatggagca agtattaaaa aatgaacaac ctaaactacc
    17581 aactacatat aaagaagcat tacaacatct tatagagcaa gtagaagtaa atgagaaatt
    17641 acaactagaa ggaaaaatga aagaccaagt aataaaagaa ctaaaaccaa aggcagatta
    17701 tacagatatg atacttaaaa acaaaggact tgtcacaata actcaaatag caaaagacta
    17761 tggaatgagt ggaaaagaaa tgaataaaat acttcatgaa agagggattc aatataaaca
    17821 aagtggacaa tggcttttat ataaacaaca ccaagggaag ggatacactc attcagaaac
    17881 aatagacata actagaagtg atggaatgac tgatgtaaaa atgacaacta agtggactca
    17941 aaagggaaga ttgtttttat atgacttatt aaaagtaaat aacatattac cagatataga
    18001 aaaagagtat agttatcaaa cttcaatgtt atgttagtac tttgaaaaat aaatacagaa
    18061 tattcaaaaa gaggtgattt aaaggttgag taatagaaag aagtatacct tgagtattac
    18121 gaaagaatta tacaataaat gtaaagaaaa agctaatcaa agaggtatgt cagtgaatga
    18181 ttacatacta tcagtgatta gcaagagtat ataaattatt cttcaatatt aattttaatt
    18241 tctccttttc tttgctcata atcttcaata tgttttttta ttatttgttc aatttcctta
    18301 ttagcagaac gaccttcgct ttcagctata tatttaattt tttcaagcag aactctgttt
    18361 attcttaaag tgtatttagg tagtgaagtt gacataataa tacctccttt ttaaagtcta
    18421 aatgatgtca taattatatc ataaaaataa tttatagaaa atctataaaa tatattgacg
    18481 gcataaagac ggcgtgatat tattaaaaca agaaaggggt tgacggcaaa atgaactcaa
    18541 ataaaaagag aataactgtt aggatgccag aaaaattaaa tgaagaaata acgaaaaaat
    18601 caaaatactt agggttaact aagaactcat ttatattaga tatactatgg aaggaatttg
    18661 agttattaga atatagaagt tataaaaagg aggtagataa acatgaataa cttacaagta
    18721 atagaaagaa ataatgagag agttctaact acacaacaat tagcagatgt atatgaaact
    18781 gactcaagaa atataagtaa caatttcaac aataacaaag ataagtttat tgaaggtaaa
    18841 cattattttt tattgcaagg tgatgattta aagaatttta aaggcattca tacagaatat
    18901 gaaaacctaa aatttgcttc aaaaatgtat ctttggactg aaagaggagc aaatagacac
    18961 tgcaaaatat tagatacaga taaggcttgg gaacagtttg ataatttaga ggaaacatat
    19021 ttcaaagtta agcaacataa gccaacttgt atagaagatg tattaataga aagtttaaaa
    19081 gaaatgaaag atttaagact tcaagttaat caagcaaata gcattgcttt agaagcaaag
    19141 acagaggttg aaacaataaa agatgtagtt tcattagact caaatagttg gagaacaaat
    19201 acacatcaac taattgcaag aatagcaaaa aaacaaggtg gttttgaaca tataaatatg
    19261 cttagaacag aaagttatga attattaaat aagagatttg gagttgacct acatagaaga
    19321 ttgatcaata aaagaagaaa aatggcagaa gaaggtgtat ctgaatctaa aagagagaaa
    19381 gttaacaatt tagatgtaat acaagatgat aagaaactca tagaagggta tgttgctatt
    19441 gtaaaagata tggctttaaa atatggaata tcaagtgatt taagcaaaaa ttaagttaaa
    19501 tcacaacagc actttgaaaa ctaaatataa aataaaaata tctcccttaa aagtttttta
    19561 aagagagata aacactttat tttgtaacta tttgaataca tgatggatga atgcaatagt
    19621 ttttatcttt gtaatttata gaaacataat tactagagta cattttatca aggttttcat
    19681 taatatattc aattgcatta cagccattta tagagccaat atcagttata tcaatccagt
    19741 tattaaatat cttaacataa acaaacttca tgataacacc aactttcatt agaatttaag
    19801 ttaattataa catggtgtac tgagataatg tgttaagaaa tagatacaga atattcaaaa
    19861 gaggtgatta gatggaaata gagcaaacaa caatacgcct gctaaaaagc agacgaaagt
    19921 tgaatattaa tttctatttt ggttaggcga aagacctaac aaaaaatctg tagatacatt
    19981 aagtttgtta gaaattaata ttaaagtttc tagatttggt tctcttgaac cagcttcata
    20041 atactgatat gcacgttctg agataccaaa caaactagca aattgctttt gagtcatatt
    20101 catttgcttt cttactagct taatattatc tttgaattta gtcataacta cacgctccaa
    20161 taaaaaaata aataaatttc ttgacacgaa caatattagc gtgtaatata taaaacatag
    20221 cacgaacaat attggcgtgt taaataaaaa ggagagggtg aaaataaata ataatttaaa
    20281 actacaacgt gaaaaaattg gcttaacaca attagaggtt gctcaaaaag ccaaaataac
    20341 agagagaagc tatcaatatt atgaagctgg cgaacgtctc ccaaacattc gtacagcttt
    20401 aaagatagct ataattttaa atactaattg tgaaaaactc tttaatgaat aatagcataa
    20461 aaggactcag attacaagaa aggagcttta gatatgaata atttgcaact taacaataaa
    20521 aatacaataa caacattaga aattgctgat atgttagaaa tcagacactg ggaagtctta
    20581 aggaaattag aaggaacaga aaaaacaaaa ggaattattg atattcttaa cgacaacaat
    20641 tttgttgtgg ttgattactt tataaaatca acatatttgg attcaaaaaa tgaaagtaga
    20701 ccttgctata atgtaacaaa attaggttgt gactttctag caaataaatt tactggagaa
    20761 aaaggtatta tttttacagc tagatatgta agaagattta atgaaatgga acgagtatta
    20821 aaagaacaac aacctaaact accaactaca tataaagaag cattgcaaca gttattagta
    20881 gaagttgaag aaaaagaaca attacaatta gaaaatcaag aaaaagataa ggtaattcag
    20941 ttacagcaac caaaagtact gtttgctgat gcagtttcag cttcaaacaa ttctatatta
    21001 gttggagaac ttgcaaaact tataaaacaa aatggagtag atataggaca aaacagatta
    21061 tttacctgga tgcgagaaaa tggatattta attaagcgta aaggtgaaga ttataatatt
    21121 ccaacacaga aaagtatgaa tctaagaata atggaagtta aaaaaagagt aattaataat
    21181 cctgatggaa gtactaaagt aactagaaca gtaaaaataa ctggaaaagg tcaagtttat
    21241 tttgttaata agtttaaaag tagtaaacaa ttatcaatgt taagttaaat cataacagta
    21301 ccttgaaaac taaatacaga atattttgga aaggagagat tgaattggaa aataagaaaa
    21361 tagaagaaat agagaaaaga ataaccatgc ttgaaaatca attgcaagca cagttattta
    21421 gtcagataac agctcaatca aatagtgatt ttatagatta tatgtaccaa tgtatagttt
    21481 tgtatttaca tgagatgaat aaaagtgaaa aaagaaaaat tagtgaaatt actaaagaaa
    21541 gaatcagaaa ataagaatga taattacaat ataaaaccta ttcttctagc aggttttgaa
    21601 gggtcagttt tctttactga agttatcata aagtttatct gtgatgtgtg ttgaagaatt
    21661 tcagaataaa ctccatttac tatgccgtag tagtgaatta gacaagggtt atgataacct
    21721 acttcttcaa caatcattaa tacatctttt ccaaagttag tcaattttag tgcaatttca
    21781 tgttcatcat caagttcttt ttcaaattcc tctatagatt taagaataat tttatattga
    21841 aattcagcat agtaaaaata ctctgtgtta gaagtatcag agactgtctt tcttatactt
    21901 tcttgtaatt ctttagatat attgtttgaa aactgcataa tacaccatcc ttttgaaaat
    21961 tttggaattt attccatgtt tatattatac catgtagaac tgaggtgaat acaatgttaa
    22021 taggcgacaa tataaagcaa atactaagaa aaagagatat aaaaccttat aaattagcaa
    22081 aggaattaaa tatagatgta agtggtctat ataaattgtt gaagaataaa aattctaatc
    22141 caactataga tactctaata aaattagctg attatttaga tattacatta gacgaattag
    22201 ttggaagata aatatttgaa aagaggggag agaattttaa catggatatt tctgaaagta
    22261 taacaaagca atttagtgat agtttaaaaa gtttaataga aatagagata aataaacaag
    22321 aaacagatag agttaagagt caaactgttg aacaaaaggt aaaagtactg gagcctaaag
    22381 atatagttgt tttaataaaa agaggttatc caaattattt gataacagta gaagaagcaa
    22441 ggggaatttt aaaattagat acagttttta tgcgtaggtt agtgagcaca ggtttgataa
    22501 aatcactggc tagaggtgat ggtagaaaaa tttcaagata tgaagttgat gattttattg
    22561 aaagaaatca aggtaaaaat ttggatgaac ttttaaaagt agcagagagg ggggatgaaa
    22621 ttgttaagcc ttaatactaa taagaataat atagtaactc ttaaaaaaga tggaaaagct
    22681 atagcagaca tagtatttaa agatattaaa actggtaaga aaatatcggt tggagtatta
    22741 aataaaaaag tgctggtcaa ataaccaaca cacaaaaaaa taaaaaataa aatataacac
    22801 aaacaaatta tagcacaaaa agaatggatt tagaataggt aatataacat tctaaaaggt
    22861 ttaatgtgta ataattgtaa caatttagaa tgtagcttat atagatagta ataaattggg
    22921 agggatttaa atggaagcag ctagactaat agcaataggt caaattaaac aagcagaaaa
    22981 agaaatatgt aaattacaag gtacaaaaaa taatagtagt ttaatgtggt gggaagccgt
    23041 aaaatttgct agtcaaaata tattagaggg tcttgaacat gacattgagt tagaagcttc
    23101 tattgagttt agagaagcta tgatgtatca agaagaactt gaaaaagata gaccaataga
    23161 tgtccagata taaaaaaaga gccttcgcac aggctctaag tgaaaataag ttacaaaaat
    23221 tataggtata ttataacata agggggaata aatgaaaaca aaaaatgaaa taattaaggg
    23281 tttagaagat agattatttt tattaagatt tacaacagta gatgaagtag attgggatgt
    23341 aaaatttgga caaatatcag cattagaatt ttgtatagat aaacatagaa aaggatgcac
    23401 tttggaacaa ttcaaagaac atttagacga atacaaatta caagggaact atggtgatta
    23461 tatagatggt tttgtgtcag ttttagaaag aaatattaga gaaatggagg gagaaattga
    23521 tggaagtgaa taatatttac ataaaattga tggatgtaag aattaagttt aacaaattag
    23581 atataaaaaa gagtggtcaa aacaagtttg ctaactttaa atattttgag ttagcagact
    23641 tcttacctca agcaacagag ctgttacaag aagctaaatt atgccctata gtgaccttta
    23701 caaatgatta tgcaactcta acattgatta atggagagaa accaacagaa gagataatat
    23761 ttacttctcc aatgagagaa ttacaattaa aaggctctaa tgagttacaa gcattaggag
    23821 gaattgaaac atatcagaca aggtatttgt acattcagtt attaaacatt acagaaaatg
    23881 atacttttga tgctactagt ggaaaagaag attataaaag aaatgactta acaaactcct
    23941 ctattaaagc aagtgaaaat ggtcaaataa aaataagtca aaatcaaata aaaagattgt
    24001 tttcaatagg aaatacaata ggcaaagatt cagatagagt aaaaagtgaa gtgtattata
    24061 agtttaataa agaagttaaa gatttaagta aacaggaata tgaccagata tgtgttggat
    24121 atgagaaatt acaaagggaa aaaggaataa ttaagtaggt gaatttcttg aaggacagag
    24181 acaaagcaac tatagagaaa ggaaatatac ttagtgatgg gtatggtctt tcaccacaat
    24241 tggtagctag agattcatgg ctaacaacag gagcaagagc tttatatttc tatctatcca
    24301 gttttgcagg agcaagtggg acatgttatc catctaggga tattatgact catgaacttg
    24361 gtataaataa agatactttt agtaaatacc taaatgaact aaagacgagt ggttatataa
    24421 aagtatataa aaataaaact agggaaggaa ggatgcaaaa taatatatat gaggtagtat
    24481 ttgatagaag ctatatagaa agtcatatat ccattagatg taagaaagaa aataaaaaaa
    24541 accatgtccg aaaaaagcag acatggaacc atgtccgaat ttaccggaca tggttcaacc
    24601 ggacatggaa aagtcggaca ctataagtaa cagtattata aataacagtt ttaaaagtag
    24661 tatgtatata gagcaagctg tggataactc tttaaaagaa tttaagaagc tatatgaaga
    24721 aaatatagga gtagtatatc cagtcacagc tgaatggtta ttagaagtat ctaatgaagt
    24781 agatataaga gtatttaaaa gagctataga gatatgtgct gaaagaatga atatgaattt
    24841 atcatactta aaaggaatcc ttaaaaagtg gaaggatgca aatataacta catatgaaca
    24901 gttagaatca tataaattac aacatgaaaa taaaaagtca aaaaaaacca atagtgtagt
    24961 aagcaaaaat aagtttgcta attttgaaca aacatttact caatacagta acaaagaatt
    25021 agatgaaatt ataaagaaaa gccaaaaggc taaatttaaa taatattgat ggaggtatta
    25081 aaatgaatca agttgtatta gttggaagat taactagaga cccagaactc aaatacatac
    25141 caggaacagg tacagcagta gcatcattta caatagctgt agacagaaat tatataaata
    25201 aagaaggaaa aagggatact gattttatac caatagaagt aataggtaaa tcagctgaat
    25261 actgtgcaaa ttacataaca aaagggaagc tagtagcatt agaagggaat ataagagttg
    25321 acaattatca aactcaatca ggtgaaaaaa gaatatttac aaaagtcagt acaaaatcag
    25381 tacaatcatt agaaagcaag aataaatcga gtaattcata taaagagagt gtacaagatg
    25441 gaaccatagg actagaccct caaggatttg aaattataga tgatgatgag ttaccatttt
    25501 aatctgaaaa attaaatatg aggtgaaata aatgtttaaa gtagaaaggt attttagtgg
    25561 ctcagtagtg gacaacctta ttgaagatga ccttacatgt agaaactact tagcattata
    25621 ttgttgtttg ttgggaatta caaaaaatgg aaaaaagata tatcctaagc cagaaaaaat
    25681 gttagctgag tttggagtaa agaaggacag aaaaataaaa aaagagttac cagtaagaat
    25741 tagaaatgtt aatacagggg aagtaaaaga atttgagtct atagatggtg cagcctgttt
    25801 tttaagatta aaatatcaag cagtttatca agctattaaa aagaaaacta aaacaagaag
    25861 tggctggaaa gttgaataca ttaaggagga ataatggaag tttcaaggac agaatataca
    25921 attaaaagag caaaagagtt atatgacaat ggagaggata tatttattgc tatagataag
    25981 gctagagaaa aatatgagga gatgattaaa agtgaatatc ttagctagtg tgatattagt
    26041 aataggaagt tttatagctg gtagagttta tgagtataga ttgaacctaa aagggtgtga
    26101 aaattgtgat aataagaagg tgcaaatatg aatgtattaa gtctattcga tggaattagt
    26161 tgtggtcaag ttgcttttga gagagctaga ataaaagtag aaaattattt tgcaagtgaa
    26221 ataaaagaga ttgcgattaa agtagcaatg aataattacc caaaaacaat acaacttgga
    26281 gatgtaagag agctaaatgt aagtaaaatc cctaaagtag atattcttat tggcggaagc
    26341 ccatgccaaa atttaagtaa aggaagatta atagctaata aaatacagga tggattaact
    26401 ggagataaaa gtaatttgtt ttgggaatat ataagaattc taaaacaatt gaatccagaa
    26461 tattttcttt tagaaaacgt agtgatgccc aaaaaagatg aaaacatgat aagccaattg
    26521 ttaggagttg aaccaatcaa gataaatagc aatttagtta gttatcaaaa tagagacaga
    26581 ttatattgga caaatatttt aaatgttcaa caacctaaag atttaaaaat tagttttcaa
    26641 gattataaag atactagttt tgattattgc aaagagtttg aaattaaaaa aactccaagt
    26701 agagaaaaaa tgtggggtaa tggtttaaat ggaaattgta agaatgtaac atatgaagac
    26761 aaaataaact gcgtaacatt aaaacaagat agatttagta attcaggttt agtagaattt
    26821 gggtctttct gcagatactt aacaactaga gaattagagt tagcgcagac gctaccagtt
    26881 ggatatacaa aaggtttgag tataagacaa gcacaaaatg tcataggtga tggttggaca
    26941 atagatgtga tagcacatat tttatcaaat attaactagt tctttatata taaattatta
    27001 ttgaagcggt tagctatcat gatacttgta gcagtaagtt ttatagctgg tagggtttat
    27061 gagtatagat tgaatctgaa agagtgtgaa aattgtaata acaactatcc tgaaaaatga
    27121 gaaagaagtg gttttatgaa taaaagaata atttgcaatt ggtgtggtaa attattttac
    27181 atcccaaaac agtctaaaaa aatttactgt tgtaaaagat gtgagagaaa ggctaagaaa
    27241 agcaatagag aacagcaaaa ttaattttaa acaataaaac tatgggggaa tagcaatgaa
    27301 taagtttcaa aaagcagttt ctcaaatggt gaagcaagag gaaaaagaaa acttgttgca
    27361 aggatatgag aattgtatag taggtagaag tatatcaagt tccataagaa gatatgtaaa
    27421 agggtttgaa aagtttggat atagtgtaca tgaggtttat gaatttataa acgatattaa
    27481 taagtatgag taactttaag tgataaagga agtatttgat tgagtaaata caataataag
    27541 aaaattgtaa tagatggaat taaatttgat agtaaagatg agtcagagta ttatttatat
    27601 ttaaaagaaa aaaaggaaaa tggagaaata aaagactttg gacttcaaca aaagtttgaa
    27661 ctacaaccta aatttaaaaa agatgggaaa agctatagag ctattacata tacaattgat
    27721 tttgccatat acaaatggaa tggtgaagtc gtttatatag atgtgaaagg gtatagtaca
    27781 cagcagggtg aacttagaaa aaagcttttt gactataaat atcaggacaa aaaattgata
    27841 tggattgcta aaagcaaaaa atatggggta gatggttgga tagaatatag tgaacttaag
    27901 aaaaagagaa aagaaaataa gaaaaaggta gcttaaataa ataggagtga tgttatggca
    27961 agtaaagtta aaaaggagtt ttttatggca actaaaaaac accttgagaa ctacaaacaa
    28021 ctacatatta atattgaaag tctaaaactt caaataaaaa atctcaaaga gttccattta
    28081 ggtgatttta tgcaaggttt aagctatgac agcattccca taagtaagac taattcaata
    28141 agtaatcaag ttgaaaatga gttaattaat cttgaagaaa agataataga aaagcagata
    28201 gaattatatg aaatggaagc actaaaatat acaatagatg tatccataag taatttaaaa
    28261 cctatacata aacaaattat aaggtatagg tatattgaag gcttagaatg gagtttaata
    28321 gttgataaag tatacttaga agaaagacaa ttaagagaaa gagctaatca agccattagt
    28381 tcaatatcaa tagccttatt tggtaaaaaa gcattaatag agcaagaacc attatttaag
    28441 atgttagatt tataggcagt taataactgt ctattttttt tgtgaaaaag atatatggaa
    28501 gttattgaca atatcacgca tacgtgatat tattgaagta tagaaaggag gcgaaaagaa
    28561 agtggctaag aaaataaaag agttcagaaa actcataaaa gaattaactg aactcgtact
    28621 cgaagttggc acactattag cagtcatcaa aatggtaata gatagcctac attagtaaaa
    28681 tgttaagagt ggaagttgca ccttccctct taactaaatt ataaaacata gtcactaaaa
    28741 atacaatgaa taagtataga gagttaacat ttgaattatt gaaactactg tatgacacta
    28801 ttaaattaat tggagcatca atattgttat attatgttat taactcaatt ttctagcaat
    28861 gattaggagg tattttatga atcgatttga aggtatttat agctttgcag aagcaacaaa
    28921 attatgggat ttgaaagatt ctacacttag aaaagcagtt gcgacaggca aattagttga
    28981 aaatattgat tgtaaaaagt ttggtcgtga ttgggtagta actattgaag caatggaaag
    29041 agaatatgga aaattaaata atataatgaa agacctagat taaattctag gtctttttat
    29101 tgccgctttt ctgccgattt tacaatttaa aatgtgagat aatagtattg tggaaatgaa
    29161 tatttctctc tcaaaactaa atatatgtgg gctaggttaa gggattcgcc tagcttatat
    29221 gaacaaacta ggcagggcat gaggatgctg taagttcaat tcttactatg ttcaaactta
    29281 ttaatacact atatgtagat atgctggatt aaaacggaat ttaattcaaa tgtctaaaag
    29341 agtggggctt ggtaacctca ctcaatttgc aaggactggt gtgtaatctt aggttcgatt
    29401 cctaaaactt gctcccttaa atataatatg tatccccaaa aaaaggctta gattaaattc
    29461 taagtctttt tttaataatt aatgtagata ataatattta ttgctaaaat gatgtacaaa
    29521 tatgataata taaattacat aaagatatat aaatagaggg ggattataaa tttgttaaat
    29581 gaaaagaatc taaagaacat aaagaatata ttacaaatgg tacaaatgaa acaccttaaa
    29641 gattttgaaa attggggaat taataaacga aaaaaagaaa ctgctataaa tagcttgata
    29701 aacataatac aaaatgatgg agaaaaacta gattatttta aggaatggat atcaatcttt
    29761 acaatagatg gtcataataa ttattatgtt tttaattaca atgattctga cttggaattg
    29821 gaagatttaa aaaacatagt agaagatata gtaagtgaaa atttattgga gattgatact
    29881 agtgatttag aagaaactaa ggtcatatat aaaaaaaatg atgtcataaa caaaagattg
    29941 attataagat ttatttctcc agctttaatt agctgtaaaa atgaaaatga gaatgggaat
    30001 atagaatctg gattagaaaa aactttttat tttgcaactt tatttctaga cttaagtttg
    30061 aaacaaataa tagtttctat accacatact gtaggtataa aaagcataga taatatagag
    30121 gctaaagcaa gagatttctc agaaatagca aaatattatg tatcaaaatt agaagatttg
    30181 ttaactactt ataatataca aatagaaaaa tacaatgatt ggatatatga tgctacatat
    30241 gagcttgctg aggaaggcag tgctcataat aatcctgaga taaacaaaaa atatgaagaa
    30301 aatattgata aaatagatga attcgcaaaa aagatagcta ttgcttctgg aataactgat
    30361 aaggctataa tagaaaattt caaagaggga gtgggaatac tctatgagaa tattctaata
    30421 gacgaatttg gtgtggtaga ggatgaaaat caatacagta cttttgtgca aaatggtgat
    30481 ggagtaaatt catactgtag agttgggtct aaaacagcaa ccctaaaatc aggaaaggga
    30541 catgctatag ccaagacatc tagaaacaat gaggatgtca agaatttagg tgtcatgaaa
    30601 tcattcaatg gaactttatc cagattttta attgaagtct tagataaaga attatattta
    30661 ataagaacag acacttctaa atttatagaa gagagggtga tttatgatgt tatacgaaaa
    30721 gttggagaat ataagtatac ttttaggaaa tcagagtaaa gcaaaatcta taatagaaga
    30781 attagagaaa ttaatgaaga gtgatatcat tacaccaaga ttgctggcca ggaaaactaa
    30841 agttacactt ttagaggcta caagagttct tgaattttta gttaaagaaa atgaattaga
    30901 attttttatt gttgttgaat gttctaatcc agatagcgta tatgaaaatg aaataggtca
    30961 ctataaatac ttcacttcga taaaagaatt caatgctttt tcaaaaggac aagaatgccc
    31021 aatatgtgga tgtggttata aatacaactt tgaagataca aaaataggct ttagaagatt
    31081 ggagaagtga tacagtgagt ctagatacct taaaagaata tctaagcata tgtgatgata
    31141 atttaatttg ggagcctttt tatgatgaca gtatgctatt agacgaattc tctaattata
    31201 taaaagaaat agaattatct aaggaatgga ataaatctaa aaatcatgag aaaggaaaaa
    31261 ttttagaaca attagtaaga tttataatgt ctagatttac aatattaagt gatatatctg
    31321 taaataagtc tacaacagat aatgagctag atgtttttgt taagtttaat gacaacatac
    31381 caataccatt cttatgtaat ataaaatcaa aaatagtatg tgaatgtaaa aactggaaaa
    31441 gtagaaaagt ggatgtagga atggtatcta aactagcaga aatatgcaat aaaaataatg
    31501 cgggattggg catatttatt tctttaaatg gattgacagg taaggggtgg caatatgctg
    31561 aaggaaaaag aagaaaatta tatttatcag ataagatgcc aataatatcg tttacagtag
    31621 atgaaataac gaaattaaag tataaaaggt ataatcttct gactatgata aaatgtaaaa
    31681 tgcaagcatt aatagatgag atggaatttg ctggaggaga attaagatta ttagaaagtg
    31741 aacttggatt tatagactgt ttaaatgaaa atatagaatc tttgaaaatg ttgggtttaa
    31801 taaccgaagt tgaatataac aatattaaag taagaatcaa tcatagatat gatattgtaa
    31861 actgagaact ccaaacgagt tcttttttta ttcccaaaac gacaaacaaa cgaggtggtg
    31921 gtgtgcaaga tgtgaaagaa aaagtaaaac aagattacct aaaaggtatg aaacaaaagg
    31981 aaatatcagc aaagtatgac attagtttaa atactttaaa gtcatggata aaaagataca
    32041 attgggctaa tgagaaaaag aagggtgcac ctaaaaataa aagaggtgca cccataggta
    32101 ataaaaatgc cactggtcct cctggaaata agaatgctga aaaatttggt ttcttctcaa
    32161 aatacttacc tgaagaaacc caagacttaa ttaatgagat aaaggataaa gataaatttg
    32221 atattctttg ggaacagata acaatacaat atgcagcaat aataagagca caaaagataa
    32281 tgtatgttaa agacaaggaa gaaatgatta aggaattaaa gaaatatgaa agcacagaaa
    32341 atggtgagaa gatagagtat gaatttcaat ttgcatggga taggcaagca tcttttctta
    32401 atgcacagag tagagcaatg agtgaactta gaagtttaat taaacagtat gatgaaatga
    32461 ttcataagga ttggaatttg gctacagagg agcagaaaac aagagttgag aagttgaaat
    32521 gtgaagttga taacctaagt aaagatgata ttggagatga tgagttgaaa ataagtgtag
    32581 attatggtga tagaaatgat agttagaata gattttaatc cagatttcaa ggaagc
//
LOCUS       DAJMZY010000036        32533 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.036, whole genome shotgun sequence.
ACCESSION   DAJMZY010000036 DAJMZY010000000
VERSION     DAJMZY010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 32533)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32533)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32533
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.036"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            <1..375
                     /locus_tag="OE968_001674"
     CDS             <1..375
                     /locus_tag="OE968_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HCP7218955.1"
                     /translation="ENKREESEIIKYYNKTDLLYLKNVVSNIVPSRDEFITIYKQALI
                     KKEIDLDMVNIRETFNVIPLKFFTILNVFRELNLLDFNLNYEKNSVLIRILPKPQKKL
                     DLNESLILNNLKNLEKQYNSSY"
     gene            388..900
                     /locus_tag="OE968_001675"
     CDS             388..900
                     /locus_tag="OE968_001675"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HCP7218956.1"
                     /translation="MDLKNFIRNIDDFPKPGIDFKDVTTLFKDGDAFKYAVDSIVEEL
                     KDKDVDLVIGPEARGFLMGTPVAYALGVGFVPIRKPGKLPGEVESYEYGLEYGTDTLE
                     IHKDAIKKGQKVAIVDDLLATGGTMEAAAKLVEKLGGEVVSMQFLIELKFLNGREKLS
                     NYDVNSLIKY"
     gene            974..3181
                     /locus_tag="OE968_001676"
     CDS             974..3181
                     /locus_tag="OE968_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003229747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HCP7218957.1"
                     /translation="MHDKELQEIIEKIKVYAPNANFEMVEKAYNLAKKAHEGQYRKSG
                     EPYFIHPLAVANILIEMELDIETITAGLLHDVVEDTEYTYEDIKKEFGKEVADLVDGV
                     TKLGQIKYRSKEETQSENLRKMFLAMAKDIRVILIKLADRLHNMRTLKYMPPEKAKYK
                     AKETLEIYGGIAHRLGISKIKWELEDRALRFMDPEGYYDLVSRVSMKRSQREDYIQGI
                     VELLKDKFKDLSIPCDVYGRPKHFYSIYRKMQKKHKTFEEIFDLTAVRILVDNVKDCY
                     AVLGIVHTLWRPIPGRFKDYIAMPKPNMYQSLHTTVVGPDGEPLEIQIRTHEMHNIAE
                     NGIAAHWKYKEGISSKESKVEEKLQWLRQMMEWEKDLKDPQEFMDALKEDVFNSQVYV
                     FTPKGDVIELPAESTPIDFAYRVHTNVGNKCVGAKIDGRIVPIDYKLQNGNIVEVLTS
                     SNSNGPSRDWLNIVKTPNAKSRIRQFFKKERREENVDRGNTILEREFKKHDIPQKDPL
                     VEKYMALVAKKFNQPSVEDLIATVGYGGIMSSQVVSKVKDLYLKEVKKAKKEQQIQEE
                     DLNKHNISETEYSKKRKKNASQGIIVKGLDNILVRFAKCCNPLPGDEIVGYITKGRGV
                     AIHRADCPNANNNGDFFQNRLVEVSWSSAGKGKFEAEIQIKAIDRRGIVNEITHIVAM
                     DKLSLNGINARKGKDSIVSINLLVEVNDTEELKILMKKLKAIPGVESIYRMTN"
     gene            3206..3655
                     /locus_tag="OE968_001677"
     CDS             3206..3655
                     /locus_tag="OE968_001677"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003517065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HCP7218958.1"
                     /translation="MRAVVQRVSSSKVTVDENTIGQINKGLLVLLGVTHDDKSSDVDY
                     MIDKILNLRIFEDENDKMNLSLMDIGGELLVVSQFTLYGDCRKGRRPGFSNAARPELA
                     NNLYEEFVKKAKDKGVTVGTGQFAAHMMVELTNDGPVTILLDSSKSF"
     gene            3670..4284
                     /locus_tag="OE968_001678"
     CDS             3670..4284
                     /locus_tag="OE968_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HCP7218959.1"
                     /translation="MIIKKFVDSYFGVNTYVLGDEKTKKCAVIDPGGSLVETLSFVKE
                     NELNIEYIILTHGHGDHIGYVKDIKEKTGAKVVAHVDEKELLNDKNKNLSYTMRCGAQ
                     EFDADIYVNDKDKLELGELKMTFLHTPGHTQGCMCIRVEDEMFTGDTLFAGSIGRTDL
                     YSGDFNQMEKSLKKLCKYEDAVRVYPGHGPTSTLGVEKKTNPYM"
     gene            4375..5931
                     /locus_tag="OE968_001679"
     CDS             4375..5931
                     /locus_tag="OE968_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coproporphyrinogen III oxidase"
                     /protein_id="HCP7218960.1"
                     /translation="MLYVFLKGHDYKYEVAELIKLFTSEFKFKDSNANNNIESKHLIN
                     RLIYENGVLFSSTEYYENGNLKYESIQNIENMNLEFLDGFDSSKTIEEFLNSLDSESK
                     RNFKKLCKENIKKSMFLVLKQVFNSYVPWGILTGIRPVKIVHNLMDKKLDDNSIRTIL
                     KDNYFIIDEKIDLALEIAKRERLFMYPIDKNKISLYVSIPFCPTRCVYCSFPSNSLKQ
                     FGHLKREYVYKLIEEIKGFAKVIKDTKKEVETLYIGGGTPTTLDEEELDLLINSLFNE
                     LDLSKIKEFTVEAGRPDTITEQKLRVLKKHNVSRISINPQTMNDDTLVKIGREHRVSD
                     LVDCFNMARRMGFDNINMDIILGLIDEDLNMVKNTLEEIKKLSPESLTVHTLAIKRAS
                     NLNINMDRYKEHLTQYEEMVKMIDLSMKYAKDMGLNPYYMYRQKHMLGNLENIGYAKE
                     GYECIYNIQIMEEKQSNYALGAGAISKFVYVDEDRIERVENVKNVEQYIERVDEMIKR
                     KKEEVYKNVD"
     gene            5921..7183
                     /locus_tag="OE968_001680"
     CDS             5921..7183
                     /locus_tag="OE968_001680"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HCP7218961.1"
                     /translation="MLTKAPRGTKDITPKEAYKWRYVENKFREICALYGYEEMVTPIF
                     EHTELFKRSVGDTTDIVQKEMYSFKDKGDREITLKPEGTAGVVRAFIENKLYADTQPT
                     KLFYVTPCFRYERPQAGRQRQFHQFGIEALGSDTPSMDAEIIALAVQFFNEVGLNDLV
                     VSINSVGCPVCRKEYNALLKEYLDSKADILCDTCNERREKNPMRVIDCKNPTCKENIK
                     DIPFIADHLCDDCKSHFDKLQEYLKEMNINFVIDKTIVRGLDYYRKTAFEIISNDIGA
                     QSTVCGGGRYDGLVEQLGGPKGISGIGFGLGIERLLLTLEGNGIEIENPQSTDIFIVT
                     IGEEANTRSFKLLKDLRQNHISADKDHIERSVKAQFKYSDKINSKFTIVIGDDELKND
                     TATLKNMKTSEQTTVKLSTLVEELKQKL"
     gene            7257..9044
                     /gene="aspS"
                     /locus_tag="OE968_001681"
     CDS             7257..9044
                     /gene="aspS"
                     /locus_tag="OE968_001681"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HCP7218962.1"
                     /translation="METLKGLKRTHYCGELREKNINEEVVLMGWVQKKRNLGGLVFVD
                     LRDTSGLCQIVFDTDVDKEAFEKAEKLGAEFVIAVKGKVCERQSKNPNMLTGDIEIFA
                     TELRLLNKSETPPIYIKDDDDVSEALRLKYRYLDLRKPSMQRNLKLRHKVMNITRNYL
                     SNNRFCEIETPFLIAPTPEGARDYLVPSRVNPGKFYALPQSPQLYKQLLMVSGMDRYF
                     QIVKCFRDEDLRADRQPEFTQIDCEMSFVEQEDVMSMIEGLLEAIFKEVLDVELALPL
                     PKMTYAEAMSKYGSDKPDTRFGYELTDISDVVCNCGFKVFADATQPGKSVRGINVKGK
                     ADDFTRKQISSLEEHAKTYRAKGLAWMKVGQEGVTSPIAKFFNEEEMNAILTRMNAEV
                     GDLLLFVADKNSIVFDALGQVRLEVANRLNLLDKNVYNLLWVTEFPVFEEDEETGTFS
                     AMHHPFTSPMDEDLDKLEEGDKSSLRAKAYDIVLNGYEIGGGSVRISNSDVQSRMFKA
                     LGFTEERANEKFGYLLEAFKYGTPPHAGLAFGLDRLVMLLAGTDNIREVIAFPKNQNA
                     VCPMTNAPTLAEDEQLEELSIKVDIKDNE"
     gene            9503..10735
                     /locus_tag="OE968_001682"
     CDS             9503..10735
                     /locus_tag="OE968_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytosine permease"
                     /protein_id="HCP7218963.1"
                     /translation="MQEREELVLNPVPKEERVGWLAPLFNMLGSNIAISELMVGGTLI
                     LGMTLSNMIITSIIGNLILVAIIMIQGYIGYKEGLNTYVLAKGAFGEIGGKYLISLLL
                     GITSFGWFGVQAGVAGLSVQKIFPSVNLTLVTVILGLFMVVFALYGFKAMAKFNYLVI
                     PPLMILMVWGVFKAFSTYGVEAIYNYTPQTTMSMVEGLNIVVGLVIVGAIISPDQLRY
                     TRRVKDIWIISFLGLGIISLFQQVAAGVMSMGAPTWDITEVLANLGFGWVAFVILILA
                     SWSTNVSNAYSGGLALKTIFPNVKRNVLTLVAGLIGTIIAATGIIFKFQSFLSFLGIA
                     VPAIAGIMWCEYYFIQGRTYKHREGINWIAVISWLIGFAASYYSSKINFLIPPINGIV
                     VSMVIYYILMKCFGIKDK"
     gene            10749..11555
                     /locus_tag="OE968_001683"
     CDS             10749..11555
                     /locus_tag="OE968_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-nitrogen hydrolase"
                     /protein_id="HCP7218964.1"
                     /translation="MGRKVKIGIIQQHSVLGDVKKNIEKAVEMIDDLGKQGADIICLP
                     ELFATGYNLESLGGVKTLELIREHNKYIEESMSEAAKRNNVYLISPYGTLEKGSTHVY
                     NSAVIFDRKGKIMGEYCKNHLWSLEAVYFKGGEKVEVYDADFGRFGVMICYDAGFPEV
                     SRELTLKGSEIIFIPSAWRIQDEDMWDLNVSQRALENTVYTVGVNLVSNDSNLILFGK
                     SKICNPRGTVITQLDTYREKYVLSEIDLDEIKKYREDIPYLKDRKSSYNI"
     gene            complement(11667..12536)
                     /locus_tag="OE968_001684"
     CDS             complement(11667..12536)
                     /locus_tag="OE968_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCP7218965.1"
                     /translation="MDLLHLKYFQTVARMEHITKASHKLNIAQPALSKTISSLEKELG
                     VQLFDRKGRYIVLNEYGRLFLKRVDSILDLVESSKKELQDTSLENSGEVKILSPAAAN
                     VLPSLLSNFRKLYPNITFNVSHTLPSSYKKSDFDLYISSSFTKLNSENSITLTCEEIL
                     LGVSINHPLSLKDEVYLSEVSDENFIVITKGENYREVIDILCESANFKPKIAFESDSP
                     YTIYALIKSLQGVGFICGKSWGLSQDPEIKLLHIKDIEFKRYLNLSWFSENYESKAVL
                     LFKNFLINYFKNI"
     gene            12908..14335
                     /locus_tag="OE968_001685"
     CDS             12908..14335
                     /locus_tag="OE968_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp14"
                     /protein_id="HCP7218966.1"
                     /translation="MKLTKSISSMLCLSLVLSLSPVAYANEISRTTVENTLVGQDRYQ
                     TAVEVSKKGWSSANEAVVVNSESIVDALAVTPFAKLKNAPILLTEKNNLNSQTEKELK
                     RLGVKKVYIIGLSSSVSNDVQKQLESNNLTTDRVGGSDRYQTALSIAKKIEGLKDISE
                     IAVVNGYTGLADAVSIGSVAATNGMVILPVSDASGISSFKDFIESKNINKSYIIGSTN
                     AVSDKIKQSLPNSERIGGADRNETNGKVIEKFYTSNKLNNVFVAKDGMKNQNQLIDAL
                     AVGVLASKENSPVLIVGEQLSATQKSVFSNKNATSITQVGSGGNENAFKELKDLQANS
                     NNKRVMYVTNTDKVNIRNDATIEASVIGYLNNGDEVEVLDVLKTGWVKIKYNEGIGYV
                     SGSYLTNNKPDNSNENIKIKYVKEKDGLNVRKGPSTEDEKIGHLSYGSKVETIEMFAT
                     GWVKIKYNGGYGYVSNDYLSDTPVI"
     gene            complement(14412..14681)
                     /locus_tag="OE968_001686"
     CDS             complement(14412..14681)
                     /locus_tag="OE968_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218967.1"
                     /translation="MKFEYYYLIQDIAGILLAFIGLRMSIIGFRILSMRGLSINTLLI
                     VIKYCLFTIAGLNLLISKFGIRHWIWSVCMLIISIIINPRIKVSK"
     gene            complement(14684..16126)
                     /gene="nhaC"
                     /locus_tag="OE968_001687"
     CDS             complement(14684..16126)
                     /gene="nhaC"
                     /locus_tag="OE968_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HCP7218968.1"
                     /translation="MKMNTERKIPSFRYSLLVMLAIIALTSVGIVVFNASITTMFLLS
                     WLIVVPAAMKLGYTNDEIEAFGFEVGKDAFQSNLIILSVGVLIAAWIAAGTIPTVVYS
                     GLTIITPKYFLLTTLIVCSLTSVATGTSWGTLGTSGIAMMSIGTSMGIPLGLTAGAVI
                     SGAFFGDKMSPLSDSTNLAAAVCKTDVITHMKHMFYTTGPAYVICIVLYTVIGFKYSN
                     NTIDYVQINQIKDVLNSNFHIGLVAMIPIIFLLLLLLLQKPPIISILSSAIMGLIIAV
                     FQEGEKIGDVLNYMLSGFTIDTGFVYADKLLNRGGIMSMAETVLLVFVVFVIAGILQK
                     TGFLEVLLQPLITKIGKSRTKLVGSTFIVSYFANAFSSSMMFTSVFVGTLMSPIYKEF
                     KLKPQNLSRIIEDTATLGGPLIPWNSNAVFCAQTLGVSPLEFIPYCFLSWITPIISFI
                     YGVTGFTMLTYTDDEIEELEIFDTAQRRVD"
     gene            complement(16151..17317)
                     /locus_tag="OE968_001688"
     CDS             complement(16151..17317)
                     /locus_tag="OE968_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HCP7218969.1"
                     /translation="MNYNFNEIVDRSNNFSSKWSEMEKKYGTNDLLPMWVADMDFKAA
                     PCIIDSLKNRLEQEIYGYTTRPDSYNESIVNWLDRRHNWKIKSEWLIYSPGVIPAISL
                     LINELTKANDKIMIQEPVYSPFNSVVKNNNRELIISPLQKLENGNYIMDYEDIENKIK
                     DVKLFILCNPHNPVGRVWTKDELKKLGDICLKHNVKIISDEIHSDIILKKHKHIPMAS
                     ISKEFEKNTITCMAPTKTFNIAGLQSSYVILPDEKYYKLLDDAFTRIDIKRNNCFSLV
                     ATEASYNNGESWLESFLEYLESNIDFAIKYINENMPKLKVRKPEGTYLLWVDFSALGL
                     SDEELESILVQKGKVALNQGNSFGIGGSGYQRINLACPRSMLEEALIRIKNAIN"
     gene            complement(17542..19662)
                     /locus_tag="OE968_001689"
     CDS             complement(17542..19662)
                     /locus_tag="OE968_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HCP7218970.1"
                     /translation="MKQMELAIVSLKKDAGEIYENQIRQFLGDNLKINLYSFEEGNLK
                     FFKEKLILLSAYLKYDEIVKLSHYDAQIIVPKLTFEKNSIDMISKLEKDKIIYVYNLS
                     KDMAIETISLIHRLGIDNINILPCYPEIEFTPTDAVILTPGEKILPKFKNCEVIDLKY
                     RIIDLSCIVEIATKTKLKHLIKDDLIKKYVEKIIPTSYSTGELLLDANKFERQFDLLL
                     SIIDDGIICTNNDGIIQFYNHMARKILSINANEMIDSFVGDCIKDINFQSILTNKTPF
                     FEKLIKINHIDINLEIKHIQLNVFDGFILKMTKFSQLEKKQAKLRAQLVNSGNISKYT
                     FDDILGSSIQTINTKKIANKMAQSNSSILIIGESGTGKELFAQSIHSASRRKDGPFVA
                     VNCSTFQENLLQSELFGYDEGAFTGAKKGGKIGLFELANNGTIFLDEIGEMDLNSQSK
                     LLRVIQEKQVRRIGSNNVIDIDVRIIAATNRNLKELVSKNMFRRDLYFRLNVLPLKIH
                     PLRERPADIFEIFGSLKYDIPCNFILSEEVKEIFKMYRWEGNVRELRNLGEYFCYLEK
                     DIIEICDLPEYILDTIDSNYSRTVCNKVSNNIKKYQFNIGKDKNIMKYDYNFKRSLDE
                     YIFILDNLKKAYDLKERIGRKSLCKIALEENRFLTEQQIRNMLLELQDFGLVDILVGR
                     GGSIITSKGVEFLKNINRSNKLNS"
     gene            19895..20296
                     /locus_tag="OE968_001690"
     CDS             19895..20296
                     /locus_tag="OE968_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218971.1"
                     /translation="MKKCLYCNRDIKSPNNKLAIKYDDNMNIYPCRAECKEKIEEYIA
                     KKPTYKFINILEVLLGVGGIFCFLSKWTIAAQVVLGIDALVIFLFPLAGFKMNGKLSM
                     EQTKNQSRSIAISILAFIVIITVLYFKQIGK"
     gene            20339..20632
                     /locus_tag="OE968_001691"
     CDS             20339..20632
                     /locus_tag="OE968_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HCP7218972.1"
                     /translation="MEERKLAPNNEREALIKRLKRIEGQVKGIQKMVEQERYCVDILV
                     QISAIRSAINRVGTIILENHIKGCVAESIKHDDADKTEEMIKELMDTINKFTK"
     gene            20647..21087
                     /locus_tag="OE968_001692"
     CDS             20647..21087
                     /locus_tag="OE968_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SoxR reducing system RseC family protein"
                     /protein_id="HCP7218973.1"
                     /translation="MNQQGFIMEIVDDRTAKLKMQRHSACAACGKCATTNSAESKEIL
                     VEVDNTIGAKVGDHVEVSMDNMNVLKAAVMAYIIPLIALLVGTIGTYYILGAIGMTTG
                     VEAISGLVGICLTIICYLYLKKNDKKFRDSREFIPVITRILIDL"
     gene            complement(21179..21652)
                     /locus_tag="OE968_001693"
     CDS             complement(21179..21652)
                     /locus_tag="OE968_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HCP7218974.1"
                     /translation="MTDMSMILHFLFSGVATAGFAVFFNAPLYLLLPAGVTGGIGWIV
                     YVYLFNFTTNAVFAGFIAAALVSACSETLARKLKQPAIVFVIPGILPLIPGIGLYNTM
                     LSLIQKNYSLAMSKGTDALFLSAAIALGVLVVTSFVRTLNLLKIRKNFIPYRKSK"
     gene            complement(21652..22440)
                     /locus_tag="OE968_001694"
     CDS             complement(21652..22440)
                     /locus_tag="OE968_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HCP7218975.1"
                     /translation="MNQNEELEYKKNILKLALFVGELMIKNGAETSRVEDSVLRICRS
                     RGFYHVNIFTTPTVIIISDEKFDGFSFMKTIQSRGINLNKISLLNSFSREFVSDKEYD
                     IDNAIARLYEIQDVKPYPLWLFYSCTGIASACFACLLGGNYVLNFILTFIIAIFAAIT
                     YDKTMKISAISAFSCLVSSFLIALSGVLLVEIGILDDPKMLIVGAIMPLLPGVAFIKA
                     IRDLISGNLISGISRAFDAAMIIIAIASGVGFVLDTWYRIGGPF"
     gene            22768..24012
                     /locus_tag="OE968_001695"
     CDS             22768..24012
                     /locus_tag="OE968_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HCP7218976.1"
                     /translation="MFENLKKADPEIYESMKRELKRQQRNIELIASENIVSVPVMETM
                     GSHLTNKYAEGYSGKRYYGGCEYIDEVETLAIDRIKKIFGAEHANVQPHSGANANIGV
                     YFAMLKPGDVVMGMNLSQGGHLTHGAPVNISGQYYKFYEYGIDKDSGLIDFDEVRKIA
                     HEVKPKMIVAGASAYPREIDFKKFREIADEVGALLMVDMAHIAGLVAAGLHQNPCEVA
                     DFVTTTTHKTLRGPRGGVILCKEKYAKDIDKAIFPGIQGGPLEHIIASKAVCFKEALS
                     DEFKEYQVQVAKNAKALAEELIKRDFKLISGGTDNHLILLDLTNKNITGKAAEKRLDD
                     AYITANKNTIPFDPNGALVTSGIRLGTPAVTTRGMKEEDMAIIAEAIDLCLTYDEESK
                     ARTLVVGLTEKYPLYEEYNIMD"
     gene            24335..25432
                     /locus_tag="OE968_001696"
     CDS             24335..25432
                     /locus_tag="OE968_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-diphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HCP7218977.1"
                     /translation="MKVLILTGKFGMGHYSASNSLSEDIKAKFDNSEIIIKDIFEYIM
                     PNYSDKMYKTFSILVNRGSSLYNLFYKCAENGKKDIKFTFSDYFLNKLDTLLHEVQPT
                     VVISTFPFCSQLVSRYKEKYNSNLPLITCITDISSHSEWISKNTDCYLVASKSTKEEL
                     VFKGIDESKIKVNGIPVKKEFKRIEHVNHSTKKNILIMGGGLGLLPKSEQFYKELNSL
                     EGVKTTVITGNNKKMYYKLYGRYENIEVVGYTNEVYKYMKDSDLIISKPGGITLFETI
                     YSELPILAFNPFLQQEIDNASFILNNEIGRILGKNKKYYVDEIKDLIYDDATLKEMSS
                     NMKELKKQFDNNTLENILFSLDEQGACRECM"
     gene            25423..26121
                     /locus_tag="OE968_001697"
     CDS             25423..26121
                     /locus_tag="OE968_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HCP7218978.1"
                     /translation="MYVVGLIIVVALIFLVHSIIPTYYNKLLNKEVLKNMAGENEIAL
                     TFDDGPDKRYTEKLLDVLKENDIQAMFFVVAKNAEKEPEIIKRMLRENHIVGLHSLEH
                     RNAWLYSYSYVKKDFIESTNIMKNLGVDVNYYRPPWGHTNIFSNSFVKKYNLKMTLWD
                     VMAEDWEKDSTVDIIINKLMSRTKENSIICLHDAGENSGGAVGAPERTIEALKIAIPK
                     LKASGLKFVTPERM"
     gene            26124..27188
                     /locus_tag="OE968_001698"
     CDS             26124..27188
                     /locus_tag="OE968_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HCP7218979.1"
                     /translation="MISKTEKKNKCLGSVAFLVLLMGITGYFVFRGQSVESLIKSLKG
                     ASPMFILIGFAMMFIYVACEGINIYLGMKALNQKTTLLKCMGYAFIGFYFSSITPSAS
                     GGQPAQVYYMKKDDINISYSSLILLVIVVIHQVVILAYSGIMFIMEREFILNNVSGMN
                     ILLIYGVITNVALVIGVIAIIFSKKLVNNFIISITNLLGKLRIIKDVESSRKVIISQI
                     EEYVKGAQYIKQNPKLVVQILVITIVQITSMFLVPFFVYKAFHLSTYTVFEILAIQSL
                     LNIAVSSLPLPGAVGASENSFMTLFKIFFPGHLLVPAMLLSRGISFYAFVAISGLICI
                     VVHVKSSEKVKAVKKVAYVR"
     gene            27371..28075
                     /locus_tag="OE968_001699"
     CDS             27371..28075
                     /locus_tag="OE968_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCP7218980.1"
                     /translation="MNKEIPKKILVADDNPEIREIVEILLTGEGYEVIMATNGEEAVN
                     LVDSTIDLIILDVVMPVKTGFVACNEIREKTTAPILFLTAKTQDSDKVIGFSAGGDDY
                     LSKPFSYSELISRVKSLLRRYYIYQGKEKEREPNILKTKELCVNLDTQDVTLNGEPVF
                     LTTIEYSILILMLKNRKKVFSSENLYETIWDEQYFYTANNTIMVHIRNLRKKLEKDQK
                     NPQYIKTAWGKGYYID"
     gene            28068..29390
                     /locus_tag="OE968_001700"
     CDS             28068..29390
                     /locus_tag="OE968_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HCP7218981.1"
                     /translation="MINKIKPSKLGVILLIYVVISAAVAFILNIPFYSAVESIVKDVS
                     EGKVYFKREVNQLMDNFQTYVNNNGIRADDGDDIAKWNSDNWFVSMKIYKGNKVFYDT
                     LYYPNEVPDKSEENEFYSSPMARNYEIQFSDIKANIVVVALFRFRFQNFIEAISITFM
                     ALTFIITFLLLFSRKIKYLRKIEMGIKIVESGSLKYRIPVKGNDELSSLASSINEMSH
                     TLENQLIKEREMKNKNKDIVTSISHDVRTPLTSVICYLDLIKDHKYNSPEQLEQYIKN
                     VRSKAYQIKDLTDDLFTHFVNSGEEVSKGYEKINANEFIFQLLLDSSYTLEEKGFHIT
                     IENELYNQYHIYVDVTQFRRIFDNLCSNIIKYARKDKPIVFLIKVEDSKLLIIQKNRV
                     SNFSKNVESFGIGIKNCEKIVAYHNGSINVNSDDKEFAIEISIPAKES"
     gene            29577..30950
                     /locus_tag="OE968_001701"
     CDS             29577..30950
                     /locus_tag="OE968_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218982.1"
                     /translation="MVLTGAHYIYILFMVIILITMIMKKDTIVPCILGVFFMGLFFEK
                     NIFGAITAVFNSFIISLNELGPIILIIAIMVALSKALEANNAIQYMVRPFSRVIKNSN
                     TAFFVTGFVMLVLSWFFWPTPAVALVGAVFLPVAMRAGLPAIGVAVALNLFGHGLALS
                     TDFVIQGAPSITAGAAGVAVSYVINDGMILFWVMGIVTISMAFYTLKRDINKGMFREE
                     LKGFESEEVEAFNGKSKIATILVALGFLADIIAMYVFDLKGGDASALLGGTAVFLIII
                     INVINFGKDSLENVCENIIDGFVFGIKIFGAIIPIAAFFYMGEVAPLTGVFGKVLAPG
                     SQGLLSDIGIALSQTIPLNKFAVSGIETVVGAITGLDGSGFSGISLVGSLASVFGTAI
                     NASVGALAALGQISGIWVGGGCLVPWGLISAAAICGVSPIELAKRNFVPVITGLVVTT
                     IVAMFII"
     gene            complement(31322..32260)
                     /gene="pdaA"
                     /locus_tag="OE968_001702"
     CDS             complement(31322..32260)
                     /gene="pdaA"
                     /locus_tag="OE968_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="delta-lactam-biosynthetic de-N-acetylase"
                     /protein_id="HCP7218983.1"
                     /translation="MFRKVLHYLTLLSISIFFIVGCSNSQNNQNENQNKETQLQEDKE
                     KIDSGKDTSNVIVSDGTDKPSKATTNNDNNKLDVSSLDNTTLDWFYIPNNKHKTPEVN
                     TDIEFKFSDYDALYNGPTKDGQKTLYLTFDEGYENGYTTKILDTLKQNQVKAVFFVTA
                     PYIKENKDLVKRMVSEGHIVGNHSKTHPSMPTKTSNLKNFNDELYDVEKLYKDVTGKD
                     MVKFFRPPMGKYSEKSLAMTKNLGYKTVFWSFAYRDWDTDKQPSHEEATQKIMDNLHD
                     GSILLLHAVSKTSTEILNDFISNARKLGYEFELLEY"
BASE COUNT        12320 a         3882 c         5454 g        10877 t
ORIGIN      
        1 gagaataaaa gagaagaaag tgaaattata aaatattata ataaaacaga cctattatat
       61 ttaaagaatg tagttagtaa tatagttcca tcaagagatg aatttataac aatttataaa
      121 caagcactca taaaaaaaga aattgatttg gatatggtaa atataaggga aacttttaat
      181 gtaattccat taaagttttt tacgatatta aatgtattta gagaattaaa tttacttgac
      241 tttaatttaa attatgaaaa aaattctgta ctcataagaa tattgccaaa accacagaaa
      301 aaattagact taaatgagag tttaatactc aataatctaa aaaatttaga aaaacaatac
      361 aatagcagtt attaggaggc gtttcccatg gatttaaaaa actttataag gaatattgat
      421 gatttcccaa agccaggcat agattttaaa gatgtgacaa ctctatttaa agatggagat
      481 gcatttaaat atgcagtgga ttctatagtt gaagaattga aagataaaga tgtagattta
      541 gtaataggac cagaagcaag aggatttttg atgggtacac ctgtagcata tgctttagga
      601 gtaggatttg ttccaattag aaaacctgga aagttaccag gtgaagttga gagttatgag
      661 tatggattag agtatggtac agatacttta gagatacata aggatgcaat taaaaagggt
      721 caaaaagtag caatagtaga tgatttattg gctactggtg gaactatgga agccgctgcc
      781 aagcttgtag aaaaattagg tggagaagta gtttctatgc aatttttgat tgagctaaaa
      841 ttcttaaatg ggagagaaaa gttgtctaac tatgatgtta attctcttat aaaatactag
      901 tacttttata atagttggta taacaccaac tattttcata tatattaaaa ttttatacaa
      961 aataggtggt tatatgcatg ataaagaatt acaagaaata attgaaaaaa taaaagttta
     1021 tgcacctaat gcaaattttg aaatggttga aaaagcctat aatcttgcaa aaaaagcgca
     1081 tgaaggacaa tatagaaaat ctggggaacc atactttatt catccattag cagttgcaaa
     1141 tattttaata gagatggaat tagatattga aactataaca gcaggtttac ttcatgatgt
     1201 tgtagaagat acagaatata cctatgaaga cataaaaaaa gaatttggca aagaagtagc
     1261 ggatttggtt gatggagtaa ctaaacttgg tcaaataaaa tatcgttcga aagaagaaac
     1321 tcaatctgaa aatttaagaa aaatgttttt ggcaatggcg aaggatataa gggttatact
     1381 tataaaactt gctgatagat tgcacaacat gagaacatta aaatacatgc ctccagaaaa
     1441 agcaaagtat aaagcaaaag agacacttga aatttatggt ggtatagctc atagattagg
     1501 aatttccaag ataaagtggg aactagaaga cagagcatta agatttatgg acccagaagg
     1561 gtattatgat ttagttagta gagtatcaat gaagagaagt caaagagagg attatattca
     1621 aggaattgtt gaacttctta aagataagtt taaagattta agtataccat gtgatgtata
     1681 tggtagacca aagcattttt acagtatata tagaaagatg caaaaaaaac ataagacttt
     1741 tgaagagatt tttgatttaa cagcagtaag gatattggtt gataatgtaa aggattgcta
     1801 tgcagtactt ggtatagttc atacattatg gagacctatt ccaggaagat ttaaagatta
     1861 tatagcaatg ccaaaaccca atatgtatca atcattacac accactgttg taggtcctga
     1921 tggagaacct ttagagatac aaataagaac tcatgagatg cataatatag ctgaaaatgg
     1981 tatagcagcc cattggaaat ataaagaagg tatctctagc aaagagtcaa aggttgaaga
     2041 aaaacttcaa tggttgagac agatgatgga gtgggaaaaa gatttaaaag acccacaaga
     2101 gtttatggat gcacttaaag aagatgtatt taatagtcaa gtttatgtat ttacgccaaa
     2161 aggagacgta attgaattac cagcagaatc aacacctata gattttgcct atagagttca
     2221 tacaaatgta ggtaataaat gtgtaggagc taaaattgat ggaagaatag ttcctattga
     2281 ttataagctt caaaatggta atattgtcga ggtacttaca tcatctaatt ctaatggacc
     2341 aagtagggat tggcttaata tagtgaagac cccaaatgca aaaagtagaa ttagacaatt
     2401 tttcaagaag gaaagaagag aagaaaatgt tgaccgtgga aatacaatat tagaaagaga
     2461 atttaagaag catgatatac cacaaaaaga ccctcttgtt gaaaaatata tggcattagt
     2521 tgctaagaaa tttaatcagc caagtgttga ggacttaatt gccactgtag gttatggtgg
     2581 tataatgtca tctcaagtgg tatctaaggt aaaagaccta tatttaaaag aggttaaaaa
     2641 agctaaaaag gaacaacaga tacaagaaga agatttaaat aaacacaata taagtgaaac
     2701 agaatacagt aaaaagagaa agaaaaacgc atcacaagga attatagtaa aagggcttga
     2761 caatatctta gtaagatttg ctaagtgttg taatcctctt ccaggagatg aaattgtagg
     2821 atatattact aagggtaggg gagtagccat acacagagct gattgcccaa atgcaaacaa
     2881 taatggtgat ttcttccaaa atagattggt ggaggtttca tggagttcag caggaaaagg
     2941 taagtttgaa gcggaaattc aaataaaagc tattgacaga agaggaattg ttaatgaaat
     3001 aactcatatt gttgcaatgg ataaacttag tttaaacgga ataaatgcaa gaaaaggtaa
     3061 ggatagtatt gtaagtataa acttacttgt agaggttaat gacacagagg aattaaaaat
     3121 tctaatgaaa aaattaaaag caattcctgg tgtagaaagt atttatagaa tgacaaatta
     3181 gagttaaaat aatagggagg aaactatgag agcagtagtg caaagagtat cttcatctaa
     3241 agttacagta gatgaaaaca ctataggtca aataaataag gggttactag tattgttagg
     3301 agtgactcat gatgataaat caagtgatgt agattatatg attgataaaa tattgaatct
     3361 gagaattttt gaagatgaaa atgacaagat gaatttatct ctaatggata taggtggaga
     3421 gcttttagta gtatctcaat ttactttata tggagattgc agaaaaggaa gaagacctgg
     3481 atttagtaat gcagctagac cagaacttgc aaataacctt tatgaagaat ttgtaaaaaa
     3541 agcaaaagat aaaggtgtga cagttggtac aggtcaattt gcagctcata tgatggtaga
     3601 gttaactaat gatggtccag taacaatact attagactca agtaaatctt tttaaggggg
     3661 aaaactttaa tgattataaa aaaatttgta gatagttatt ttggagtaaa tacttatgta
     3721 ttaggtgatg aaaagactaa aaaatgtgca gttatagacc caggtggaag tttagtagag
     3781 acattaagtt ttgtaaaaga aaatgaatta aatattgaat atattatcct tactcatggg
     3841 catggagacc atataggata tgttaaggat attaaagaaa aaactggtgc taaagtagtt
     3901 gcacatgttg atgaaaaaga attattaaat gacaaaaata aaaatctaag ttatacaatg
     3961 agatgtggag cgcaagagtt tgatgcagat atctatgtaa atgataaaga caagcttgaa
     4021 cttggtgaat taaaaatgac tttcttgcat actccaggac atactcaagg atgtatgtgt
     4081 ataagagttg aagatgaaat gttcacagga gatactttgt ttgctggaag tattggtaga
     4141 actgatttat atagtggaga ctttaaccaa atggaaaaat cacttaagaa attatgtaaa
     4201 tatgaagatg ctgttagagt atatcctgga catggaccaa ccagtactct aggggttgaa
     4261 aagaagacaa atccttacat gtaattttat attagtattt aaaaaagtat aaaatattta
     4321 ataactatat tagtgagggg gttcttctac tgttaaatag aaggagttaa gttgatgttg
     4381 tatgtttttt taaaaggaca tgattataag tatgaagtag cagaacttat aaaattgttt
     4441 actagtgaat ttaagtttaa agactctaat gctaacaata atatagagtc aaagcattta
     4501 ataaatagat tgatttatga gaatggtgta ttattctcaa gtactgaata ctatgaaaat
     4561 ggaaacttaa agtacgagtc aatacagaat atagaaaata tgaatcttga atttttagat
     4621 ggatttgata gcagcaaaac gattgaagaa tttcttaata gcctagatag tgaaagtaag
     4681 aggaacttta aaaagctgtg taaagaaaat atcaaaaaaa gcatgttttt agtgcttaaa
     4741 caagtattta attcttatgt accatgggga attttgactg gtattagacc agtcaaaatt
     4801 gtccacaatt taatggataa aaagctagat gataatagca taagaaccat tctaaaagat
     4861 aattatttta taatagatga gaaaatagat ttagctcttg aaatagctaa aagagagcga
     4921 ttatttatgt atcctataga taaaaataaa atttctcttt atgtaagtat tccattttgt
     4981 ccaactagat gtgtatattg ttcatttcct tcaaattcat taaaacaatt tggacattta
     5041 aaaagagaat atgtttataa attgattgaa gaaattaagg ggtttgccaa agttattaag
     5101 gatactaaga aagaagttga aactctatat attggtggtg gaactccaac tacacttgat
     5161 gaggaagaat tggatttgct tataaattca ttgttcaatg aattagattt aagtaaaatt
     5221 aaagaattta ctgtagaagc aggtagacct gacactatta cagaacaaaa actaagagtg
     5281 ttaaaaaaac acaatgttag tagaattagt ataaatcctc aaactatgaa tgatgatacc
     5341 ttggtaaaga ttggaagaga gcatagagta tctgatttag tagattgctt taatatggct
     5401 cgtagaatgg gatttgataa tataaatatg gatataattt taggtcttat agatgaagac
     5461 ttaaatatgg taaagaacac attggaggag ataaaaaaac tttctcctga aagccttaca
     5521 gttcatacat tagccataaa gagagcatct aacttaaata taaatatgga taggtataaa
     5581 gaacatctaa cacaatatga agaaatggta aaaatgatag atttatcaat gaaatatgca
     5641 aaagatatgg gattaaatcc atattatatg tacagacaaa aacatatgtt gggaaattta
     5701 gaaaatatag gttatgctaa agaaggatat gagtgcattt ataatataca gattatggaa
     5761 gaaaaacaaa gtaactatgc attaggtgca ggtgctatat cgaaatttgt ctatgtagat
     5821 gaagatagaa ttgaaagagt agaaaatgta aaaaatgttg aacaatacat tgaaagagta
     5881 gatgaaatga taaaaaggaa gaaagaagag gtatataaaa atgttgacta aagctcctag
     5941 aggaactaaa gacataactc caaaagaggc ttacaaatgg cgttatgtag aaaataaatt
     6001 tagagaaata tgtgctttat atggatatga agaaatggta acacctatat ttgaacatac
     6061 agaacttttc aagagaagtg ttggagatac tacagatata gttcaaaaag aaatgtattc
     6121 ttttaaagat aaaggtgata gagaaattac cctaaagcca gaaggtacag caggtgtagt
     6181 aagagcattt atagaaaata aattatatgc agatactcaa ccaacaaaat tattttatgt
     6241 gacaccttgt tttagatatg aaagaccaca agctggtaga caaagacaat ttcaccaatt
     6301 tggaatagaa gcacttggaa gtgatactcc ttcaatggat gctgaaataa tcgcactagc
     6361 tgttcaattt tttaatgaag ttggattaaa tgatttggta gtgagtataa attcagttgg
     6421 ctgtccagtt tgtagaaaag agtacaatgc tttattaaaa gagtatcttg actcaaaagc
     6481 tgatatattg tgtgatactt gcaatgagag aagagaaaaa aatccaatga gggttataga
     6541 ctgtaaaaat cctacatgta aagaaaatat caaagatata ccatttattg cagaccattt
     6601 gtgtgatgat tgtaaatctc actttgataa acttcaagaa tacttaaagg aaatgaatat
     6661 aaactttgta attgataaaa caatagttag aggcttagat tactatagaa aaactgcttt
     6721 tgaaattata tctaatgata taggagctca aagtactgta tgtggtggag gaagatatga
     6781 tggtcttgtt gaacaattag gaggaccaaa aggtataagt ggaattgggt ttggactagg
     6841 aattgaaaga cttttactta cacttgaagg taatggaatt gaaatagaaa accctcaatc
     6901 tacggatata tttatagtaa ctataggtga agaagcaaat acaagaagct ttaaattgtt
     6961 aaaagacttg agacaaaatc atataagtgc agataaagac catatagaga gaagtgttaa
     7021 agcacaattt aaatattcag ataaaataaa ttcaaaattt acaatagtaa ttggagatga
     7081 tgagcttaaa aatgacactg cgacattaaa aaatatgaaa acatcagagc aaactactgt
     7141 aaaattaagt acattagttg aagaattaaa gcaaaagctg taaaataaga aagtatgatg
     7201 ttttgtgtat tagataaata tatagcatta aaattaaata aaatggaggt agtatcttgg
     7261 aaactttaaa gggtttaaag agaactcact actgtggaga gttgagagaa aaaaacataa
     7321 atgaagaagt cgtacttatg ggatgggtac agaaaaaaag aaatttaggt ggtcttgtat
     7381 ttgttgattt aagagataca agtggattat gtcaaatagt ttttgataca gatgtagata
     7441 aagaagcttt tgaaaaagct gaaaaattag gggctgaatt tgtaatagct gtaaaaggaa
     7501 aagtatgcga aagacaatct aaaaacccta atatgctaac tggtgatata gaaatatttg
     7561 caactgaact tagactttta aacaagtcag aaactccgcc tatttatata aaagatgatg
     7621 atgatgtttc tgaagcacta agattaaaat atagatactt agatttaaga aaaccatcta
     7681 tgcaaagaaa tttaaaatta agacataaag taatgaatat tacaagaaat tacttatcaa
     7741 acaatagatt ttgcgaaata gaaacaccat ttttaatagc tccaacacca gaaggagcaa
     7801 gagattatct agtaccaagt agagttaatc caggaaaatt ttacgcatta ccacaatcac
     7861 cacaattata taaacaatta ttgatggtaa gtggtatgga tagatatttc caaatagtta
     7921 aatgctttag agatgaagac ttaagagcag atagacaacc agagtttaca caaatagact
     7981 gcgaaatgtc ttttgttgag caagaagatg ttatgagtat gattgaaggt ttgcttgaag
     8041 cgatatttaa agaagtttta gatgtagaat tggcacttcc acttcctaag atgacttatg
     8101 cagaagctat gtctaaatat ggttcagata aaccagatac tagatttgga tatgagttaa
     8161 cagatatatc tgatgttgtt tgtaactgtg gatttaaagt gtttgctgat gctacacaac
     8221 caggaaaaag tgttagaggt ataaacgtaa aaggcaaagc tgacgacttt actagaaaac
     8281 aaatatcatc actagaagaa catgctaaga catatagagc aaaaggtctt gcttggatga
     8341 aagtaggaca agaaggagta acttctccaa tagcaaaatt ctttaatgaa gaagaaatga
     8401 acgctatact tacaagaatg aatgctgaag taggagattt acttttattt gtagctgata
     8461 aaaactcaat agtatttgat gctttaggac aagttagact tgaagtagca aataggctta
     8521 atctattgga taaaaatgta tataacttac tatgggtaac tgagttccca gtttttgaag
     8581 aagatgaaga aacaggcaca ttctcagcaa tgcatcaccc atttacatca cctatggatg
     8641 aagatttaga caagttagaa gaaggtgata agtcatcttt aagagcgaaa gcttatgata
     8701 ttgtattgaa tggttatgaa ataggtggag gaagtgttag aatatcaaat tctgatgttc
     8761 aatcaagaat gtttaaagca cttggtttta cagaggaaag agctaatgaa aagtttggtt
     8821 atttattaga agcatttaaa tatggtactc ctcctcatgc tggtctagct tttggtcttg
     8881 atagacttgt tatgttactt gcaggaactg ataatataag agaagttatt gcattcccta
     8941 aaaatcaaaa tgctgtttgc cctatgacaa atgctcctac attggcggaa gatgagcaat
     9001 tagaagaatt aagtataaaa gttgatataa aagataatga ataatatgta gttgcaagaa
     9061 actaaaatgt aaaaagtctg gatataaaat atatttatat tcagactttt tttattagaa
     9121 ttattttata ttttttctct atatattttc ataaattata cttatattct taaccaatat
     9181 aattaaaata ctatgtttaa aaattttaca taaacttgat tattttagaa actacttctg
     9241 taatgagtac acgattttaa ttaaagaata tataacaaat ttgaaataag tctaatatat
     9301 gacttaatag attaaattaa aataataaat ttggactatt tatctattta taacttaaat
     9361 tatatcaaat tgataacaaa ctagatatta tacttttttg tagaatagaa ttacaattat
     9421 ataaagaaaa attctattaa tagtgaaaaa aaagtagaaa aaagtagaaa ttattctttt
     9481 ataaagaaag ggagggataa tattgcaaga gagagaagaa ttagttttaa atccagttcc
     9541 aaaagaggaa agagttggat ggttagctcc attgtttaat atgcttggtt ctaacatagc
     9601 tatatctgaa ctaatggttg gaggaacttt aattttagga atgactcttt ctaatatgat
     9661 tattacatca attataggga acttaatatt agttgcaatt attatgatac aaggttatat
     9721 aggttacaaa gaagggttaa atacgtatgt attagctaag ggggcatttg gagagatagg
     9781 aggaaagtat cttatatctc tattacttgg tataactagt tttggatggt ttggtgtaca
     9841 agcaggggtt gcaggactat cagtacaaaa gatatttcca agtgtaaatc taacattagt
     9901 tacagttata cttggattat ttatggttgt ttttgcactg tatggcttta aagctatggc
     9961 taaatttaat tacttagtta taccaccact tatgatatta atggtgtggg gagtttttaa
    10021 agctttttct acttatggag ttgaagctat ttataattat actcctcaaa caactatgag
    10081 tatggttgaa ggtcttaata ttgtagtagg tcttgttata gttggtgcaa ttatatcacc
    10141 tgaccagtta agatatacga gacgagtaaa agatatttgg attatcagtt ttttaggtct
    10201 agggattatt tcattattcc aacaagttgc agctggtgta atgtctatgg gagcacctac
    10261 ttgggatata acagaagtat tggctaattt aggttttgga tgggtagcgt ttgttatttt
    10321 aatacttgca tcttggtcta caaacgtatc aaatgcttat tctggtggat tagcattaaa
    10381 aactattttt ccaaatgtaa aaagaaatgt tttgacttta gttgcaggtc taataggtac
    10441 aataatagca gctactggta taatatttaa atttcagtca tttttatctt tcttgggaat
    10501 cgcagttcct gcaatagctg gaattatgtg gtgtgagtat tattttatac aaggaagaac
    10561 ttataagcat agagaaggaa taaattggat tgcagtaata agctggttaa taggttttgc
    10621 agcgtcgtat tatagttcaa aaataaattt cttaatacct ccgataaatg gaattgtagt
    10681 gagtatggtt atttattata tattaatgaa atgttttgga atcaaagata aataaagggg
    10741 gcaattacat gggtcgtaag gtgaaaatag gtataattca acaacacagt gtacttggag
    10801 atgttaaaaa aaatatagaa aaggcagtag agatgataga tgacttagga aaacaagggg
    10861 cagatataat ttgtttacca gaactatttg ctacaggata taatttagag tctttaggtg
    10921 gagttaaaac attagaatta ataagagaac ataataagta catagaggaa tcaatgtcag
    10981 aagctgctaa aagaaataat gtatacctga tatctccata tggaacctta gaaaaagggt
    11041 ctacacatgt ttataattca gcagttatat ttgatagaaa aggtaagatt atgggagaat
    11101 actgtaaaaa tcatctgtgg tcattagaag cagtatactt taaaggaggg gaaaaagtag
    11161 aggtatatga tgctgatttt ggtagatttg gtgtaatgat atgttatgat gcaggttttc
    11221 cagaagtatc cagagaattg acattaaaag gttctgaaat aatatttata ccatctgcat
    11281 ggagaataca agatgaagat atgtgggatt taaatgtatc tcaaagagct ttagagaaca
    11341 ctgtatatac agtaggtgta aatttagtaa gtaatgactc taatttaata ctatttggaa
    11401 agagtaaaat atgcaatcct agaggtactg taataactca attagataca tacagggaaa
    11461 aatatgtatt atcagagatt gatttagatg aaataaaaaa gtatagggaa gatatcccct
    11521 atttgaaaga cagaaaaagt agctataaca tataattcta tactataata caagttcaat
    11581 ataaaatgat aaaaagagga tgtatcaata ttaagattaa atttattata ctttgatata
    11641 tcctctttaa tattatcaac tttgatttaa atatttttaa aatagttgat aagaaagttt
    11701 ttgaacaaca acacagcttt agattcatag ttttcgctaa accatgaaag atttaaatat
    11761 cttttaaatt caatatcttt gatatgtaac aacttaatct cagggtcttg agataatccc
    11821 catgattttc cacatataaa tccaactcct tgaagtgatt ttataagagc ataaattgta
    11881 tatggtgaat cagactcaaa tgctattttg ggtttgaaat tagctgattc gcacaggata
    11941 tcaattacct ctctataatt ctcacccttc gttataacta taaagttttc atctgaaact
    12001 tcgcttagat atacttcatc ctttaatgat aaaggatggt ttattgaaac tcctaatagt
    12061 atttcttcgc atgttaaagt tatgctattt tctgagttta gctttgtaaa tgaagaagat
    12121 atgtacaaat caaaatcact ttttttataa gatgatggca aagtatgtga cacattaaaa
    12181 gtaatattgg gatatagttt tctgaaatta ctcaaaagtg atggtaacac attagccgct
    12241 gcaggagata atatctttac ttctcctgaa ttttctaaag aagtgtcttg taactccttt
    12301 tttgaacttt ctactaaatc taaaatgcta tctactcttt ttagaaacaa tcttccatac
    12361 tcatttaaaa caatatatct tccttttctg tcaaataact gaactccaag ttctttttct
    12421 aaggaagata tagttttgct taaagctggc tgtgctatat ttaacttgtg tgatgctttt
    12481 gttatgtgct ccattctagc aacagtttga aaatacttaa gatgcaataa atccatagta
    12541 taaaatacac ctcttttaat atgacttgag ttatatcaat tttataatca actccacatt
    12601 atacattata atataaagtt tatataataa actacaatat attaaaaagt tatttaaatt
    12661 gttatttata ttttgtacat aatctaatta aaaaaagtaa ctttaaatga ttaactaagg
    12721 aaatgttgtt acaaacttta gttatataaa aaattcattt gatgagcaaa gtactaatat
    12781 caagtaagaa taaaagctta ttagataaga aaaataatat tttataataa tgatgttact
    12841 taaattatta tgttatacta ttttaaatag gaaaaattta gatactataa ttttaggggg
    12901 agtcaagatg aaattaacta aatcaatatc atcaatgctg tgcttatctc tagttttaag
    12961 cttatcacca gtagcatatg caaatgaaat aagtagaaca acagttgaga atactttagt
    13021 aggtcaggat agatatcaaa ctgctgttga agtaagtaaa aaaggatgga gtagtgcaaa
    13081 tgaggctgta gttgtaaata gtgaatctat tgtagatgca ttagctgtaa caccatttgc
    13141 taaattaaaa aatgctccta tattattgac agaaaaaaat aatctaaatt cacaaactga
    13201 gaaagaatta aaaagattag gagttaaaaa agtttatata attggtctat ctagttctgt
    13261 atcaaatgat gtgcaaaaac agttagaatc taataattta actactgata gagttggtgg
    13321 tagtgataga taccaaacag ctttgagtat agctaaaaaa atagaaggat taaaagatat
    13381 atcagaaata gctgtagtaa atgggtacac aggtcttgca gatgcagtta gtataggttc
    13441 tgtagctgct actaatggaa tggttatact tccagtatct gatgcatctg gtatatctag
    13501 ctttaaagat tttatagaat ctaagaatat aaataaatca tacataatag gctctactaa
    13561 tgctgtatca gataaaataa aacaaagttt acctaattca gaaagaatag gtggagcaga
    13621 tagaaatgaa actaatggta aagtaataga aaagttttat acatctaata aattaaacaa
    13681 tgtatttgtg gctaaggatg gaatgaaaaa tcaaaatcaa cttatagacg ctctagcagt
    13741 aggagtacta gcatcaaaag aaaattctcc tgtactaatc gtaggagaac aattaagtgc
    13801 aacacaaaag agtgtatttt cgaataaaaa tgctacctct ataactcaag ttggtagtgg
    13861 aggaaatgaa aatgcattta aagaattaaa agatttacag gcaaatagta acaataagag
    13921 agtaatgtat gtaactaata cagataaggt aaatataaga aatgatgcta caatagaagc
    13981 ttctgttata ggatatctaa ataatggtga tgaagtagaa gttttagatg tgttaaaaac
    14041 tggatgggta aaaataaaat acaatgaagg tattggatat gttagtgggt cttatttgac
    14101 aaataataag cctgataata gtaatgaaaa tataaaaata aagtatgtaa aagaaaaaga
    14161 tggtctaaat gttaggaaag gaccaagtac agaagatgaa aaaataggtc acctttcata
    14221 tggaagcaaa gtagaaacaa tagaaatgtt tgctactgga tgggtaaaaa taaagtacaa
    14281 tggtggatat ggttatgtaa gtaatgatta cttatctgat acaccagtta tttaattata
    14341 agtaacaata aaaaaactgc tttaatttgt aaagcagttt ttttataaaa atttaagtct
    14401 aataactatt tctattttga taccttaatc ctgggattta ttattatgga tattatcaac
    14461 atacaaacac tccaaatcca gtgtctaatt ccaaacttag atattaataa attcagtcct
    14521 gctatggtaa ataagcagta tttaattaca attaaaagtg tatttataga aagccccctc
    14581 atagaaagta tcctaaatcc aataatagac attctaagtc ctataaatgc caataatata
    14641 cctgcaatat cctgaattaa gtaatagtat tcaaatttca tattcaatca actcttctct
    14701 gagcagtatc aaatatttct aactcttcaa tttcatcatc tgtgtatgta agcatagtaa
    14761 aaccagttac accataaata aatgaaatta taggtgtaat ccaacttaag aaacaatatg
    14821 gaataaattc tagtggactt acaccaagag tctgagcaca gaaaacagca tttgaattcc
    14881 atggtattaa tggaccacca agtgtagctg tatcttctat aattctagat agattttgtg
    14941 gttttaattt aaattctttg tatattggag acattagagt tccgacaaat acagaagtga
    15001 acatcattga tgaactaaat gcatttgcaa agtagcttac tataaaagta gacccaacca
    15061 atttagttct tgattttcct attttagtta taagaggttg aagcagtact tctaagaatc
    15121 cagttttttg gagaatacca gcaataacga aaactacaaa tactagtaaa acggtttcag
    15181 ccatactcat tattccacca cgatttaata gtttgtcggc atagacaaat ccagtatcta
    15241 tagtaaatcc tgatagcatg taatttaaaa catcacctat tttttctcct tcttgaaata
    15301 ctgctataat aagtcccatg atagctgaac ttagtataga tataatgggt ggcttttgta
    15361 gcaataaaag taataataaa aatattattg gaatcattgc tactaaacca atatgaaagt
    15421 ttgaatttaa tacatccttg atttgattta tttgaacata gtctatagta ttatttgaat
    15481 acttaaatcc aattactgta tacagaacta tacatattac gtatgcaggt cctgtggtat
    15541 aaaacatatg cttcatatgt gtaattacat ctgtcttaca aactgctgca gctaagtttg
    15601 tagaatctga tagaggtgac atcttatctc caaagaaagc accagaaatg actgcaccag
    15661 ctgttaaacc aagaggaata cccatactag taccaatact catcattgct ataccagaag
    15721 ttccaagagt cccccaagat gtaccagtag caacagaagt taatgaacat acgattaatg
    15781 ttgtaagcag aaaatattta ggggttatta ttgttagtcc actatatact actgttggta
    15841 ttgtaccagc agctatccaa gctgctatta gtacaccaac agaaagtata attaagtttg
    15901 attgaaaggc atctttgcca acttcaaatc caaaagcttc tatttcatca ttagtataac
    15961 caagtttcat ggctgcagga actactataa gccatgaaag taaaaacatt gtagttatag
    16021 aagcattaaa tacaactata ccaactgatg ttagagctat tattgcaagc attactaaca
    16081 aggaatatct aaatgaaggt atttttcttt ctgtattcat tttcatagtg caaattctcc
    16141 ttaaatattt ttagttaatt gcatttttta ttcttataag agcttcttca agcatacttc
    16201 ttggacaagc taagtttatt ctttgatacc cacttcctcc aatgccaaag ctgtttcctt
    16261 gatttagagc aactttacct ttttgtacaa gtatactttc tagttcctca tcacttaatc
    16321 caagtgcact aaagtctacc cataataaat aagtaccttc tggttttcta actttaagtt
    16381 ttggcatatt ttcatttata tattttatag caaaatctat attagattct aaatattcta
    16441 aaaatgattc tagccaagat tcaccattat tatatgaagc ttcagttgca actaagctaa
    16501 agcaattatt tctctttata tcaattctgg taaaggcatc atctaacaat ttatagtatt
    16561 tttcatcagg tagtattaca tatgatgatt gaagaccagc tatattaaaa gttttagttg
    16621 gagccataca agtaattgta tttttttcaa attctttaga aatagatgcc ataggaatat
    16681 gcttatgttt ttttaatata atgtcactat gtatttcatc agatatgatt tttacattat
    16741 gcttaagaca aatatctcct agttttttta attcatcttt tgtccatact ctaccaactg
    16801 gattatgagg attacaaagt atgaataatt ttacatcttt aatcttgttt tcaatgtctt
    16861 cataatccat tatgtagttt ccattttcta atttttgtaa tgggcttata attagttctc
    16921 tattgttatt ttttacaaca ctattaaaag ggctgtaaac tggttcttgt atcattattt
    16981 tatcatttgc ttttgtgagt tcatttatta aaagacttat agctgggata acacctggac
    17041 tataaattaa ccactcactt tttattttcc agttatgtct cctatctagc cagtttacta
    17101 tagattcatt gtaagaatct ggtcttgttg tgtagccata aatctcttgt tctagtctat
    17161 tttttaaaga atcaattata caaggtgcag ccttaaaatc catgtcagcc acccacatag
    17221 gaagtaaatc attagttcca tacttttttt ccatttctga ccatttagat gaaaaattat
    17281 tgcttctatc aacaatctca ttaaaattat aattcattgt aaatacctcc agtaatttta
    17341 attttatgtt aataatatta agcaaacaac gtgccaatat tgataataaa aaatatttat
    17401 tcacaagtta atatttaata ttaagtaatt tcagagcata gataagataa aaatattaat
    17461 tatacttaaa actttgtgga aaaggttatt tctaataaat ttttaaatat atgaaaatgt
    17521 aattaaatag gttaaatagg tttaactgtt taacttgtta gacctattta tattttttag
    17581 aaactctact ccctttgatg ttataattga acctccacga ccaacaagta tgtctacaag
    17641 cccaaagtct tgtagttcta aaagcatatt tctaatctgt tgttctgtca aaaatctatt
    17701 ttcctctaaa gctattttac ataagctttt tctacctatt ctttctttta aatcataagc
    17761 cttttttaaa ttatccaata taaatatgta ttcatctagt gaccttttaa aattatagtc
    17821 gtatttcatg atgtttttgt ctttgccaat gttgaattga tactttttta tattattact
    17881 tactttatta caaacggttc tactataatt tgaatctata gtatctaata tatattcagg
    17941 taaatcacat atttctataa tatctttttc caagtaacag aaatattctc ctaagtttct
    18001 taattctctt acatttcctt cccatctata cattttaaag atttctttta cttcctcact
    18061 tagaataaaa ttacatggaa tatcatattt taatgaacca aaaatttcaa atatatcagc
    18121 aggtctttcc ctaagtggat gtattttaag gggaagaaca ttcaacctaa aatataaatc
    18181 tcttctaaac atatttttag atacaagttc ttttaaattt ctattagtag ctgcaattat
    18241 tcttacatca atgtcaatga cattattaga accaatacgt cgtacttgtt tttcttgtat
    18301 gactctaagt aatttagatt gagaatttaa atccatttct ccaatttcgt ctaaaaatat
    18361 agttccattg ttggctaatt caaataaacc aattttccca ccttttttag caccagtaaa
    18421 agccccttca tcatagccaa ataattcact ttgcagtaga ttttcttgaa aagtactaca
    18481 atttactgcg acaaaaggac catcttttct cctagaagca ctatgaatgg attgagcaaa
    18541 taattcttta ccagtaccac tttcaccaat tataaggata gatgaatttg attgagccat
    18601 tttattagca attttttttg tattaatagt ttgtatacta gaacctaata tatcatcaaa
    18661 tgtgtattta ctgatattac cagagtttac tagttgtgct cttaatttag cttgcttttt
    18721 ttctaattga gaaaactttg tcatctttag tataaatcca tcaaatacat ttaattgtat
    18781 atgtttaatc tctaaattta tatcaatatg atttatttta atcaatttct caaaaaatgg
    18841 agttttattg gtcaatatgc tttgaaaatt gatgtctttt atgcaatcac caacaaatga
    18901 gtcaatcatt tcatttgcat ttatagacaa aatttttcta gccatatgat tatagaattg
    18961 aattattcca tcgttatttg tgcatataat tccatcatca attatagata gtaacaaatc
    19021 aaattgtctt tcaaacttat ttgcatctaa caataactca cctgtactat aacttgtagg
    19081 aattattttt tctacgtatt tttttattag gtcatctttt attagatgtt ttaatttggt
    19141 ttttgtagca atttcaacaa tacaacttaa atctattatt ctgtatttta aatctataac
    19201 ttcacaattt ttaaacttag gcaagatttt ttcgccagga gttaggatta cagcatctgt
    19261 gggagtaaac tcaatctctg gatagcaggg caggatattt atattgtcta ttcctaatct
    19321 atgtattaaa gaaattgttt ctattgccat atctttactt aagttatata cataaataat
    19381 tttatctttt tctaatttgg atatcatatc aatactgttc ttttcaaatg tcaacttagg
    19441 aacaatgatt tgagcatcat agtgagataa ttttactatt tcatcatatt ttaaataagc
    19501 agataggagt ataagttttt ctttaaaaaa ctttaaattt ccttcttcaa atgagtataa
    19561 atttatcttt agattatcac ctaagaattg tcttatttga ttttcataaa tttctccagc
    19621 gtcttttttt aaacttacaa tagctaattc catttgtttc attttaacct ctcatacaaa
    19681 tttgacttat tttagattac ataataatta aattagatta aataatatta tttaattatt
    19741 attataaatt tattatagac tacacattga agtaaaagaa gtagctaaaa ttattccttt
    19801 tatttttgtt ttttgtatct atttggtata atagtattag agcgtataat aatttaggca
    19861 aaatttttta aggaagacta gaggagaata taaaatgaaa aaatgtcttt actgtaatag
    19921 ggatataaag tcaccaaata ataaattagc tataaaatat gatgacaata tgaatatata
    19981 tccatgtcgt gcagaatgta aggaaaaaat tgaagaatat atagcaaaaa aacctacata
    20041 taagtttata aatatattag aggttctttt aggtgtgggc ggaatattct gctttttgag
    20101 taaatggact attgcagccc aagttgtact tggaattgat gcactggtta tatttttatt
    20161 cccattggca ggatttaaga tgaatggaaa gttaagtatg gaacaaacta agaatcaaag
    20221 taggtctatt gcaatatcaa ttttggcatt tatagtaata ataactgtat tatattttaa
    20281 acaaattggt aagtagagca taattgtata agacatcatt agagtatgag gtgagtttat
    20341 ggaagaaaga aaattagcac caaacaatga gagggaagct ctcataaaaa gattaaaaag
    20401 aatagaaggt caagttaagg gtatacaaaa gatggtggaa caagaacgtt attgtgttga
    20461 tatattggtt caaatatctg ctataaggtc tgctataaat agagtaggca caattatctt
    20521 agagaatcat ataaaaggat gtgtagcaga aagcattaaa catgatgatg ctgataaaac
    20581 tgaagagatg ataaaagagc ttatggatac tataaataaa tttacaaaat aaggaggcgg
    20641 ttagttatga atcaacaagg atttattatg gaaattgttg atgatagaac tgcaaagtta
    20701 aaaatgcaaa gacattcagc ttgtgctgct tgtggaaaat gtgctactac aaattcagca
    20761 gagtcaaaag aaatattagt agaagtagac aacacaattg gcgcaaaagt tggtgaccat
    20821 gtagaagtga gtatggataa tatgaatgta ttaaaagcag ctgtaatggc ttatataata
    20881 cctcttatag cacttcttgt aggaacaata gggacttatt atatattggg ggcaattgga
    20941 atgacaactg gagttgaagc cataagtgga ttagttggaa tttgtcttac aataatctgt
    21001 tatttatact taaagaagaa tgacaaaaaa tttagagaca gtagagaatt tataccagta
    21061 ataacaagaa tattaattga cctttaagat aattataatt aaaaaatagc aatgtgcttc
    21121 ttaaataaat actcaatacg tatttgtaga gtttaagtac attgctattt ttatattttt
    21181 attttgattt tctgtaagga ataaagtttt ttctgatttt caaaagattc aatgttctta
    21241 caaaagaagt tacaactaat acaccaagtg ctattgcagc acttagaaat agcgcatctg
    21301 taccttttga catagccaaa gaataatttt tctgaatcaa agacaacatt gtattatata
    21361 gcccaattcc tggtattaga ggaagaatac ctggaattac gaacacaata gctggttgct
    21421 ttagttttct tgctaaagtc tcactgcacg ctgagaccaa agcagcagcg ataaaacctg
    21481 caaaaactgc atttgtagta aaattaaata aataaacata tacaatccaa ccaattccgc
    21541 cagttactcc agctggaaga agtagatata gtggagcatt aaagaaaaca gcaaatccag
    21601 cagttgcaac acctgaaaat aaaaaatgca aaatcataga catatcagtc attagaaagg
    21661 acctcctatt ctataccatg tatcaaggac aaaaccaact ccagaagcaa ttgcaataat
    21721 aatcatagca gcatcaaaag cacgagaaat tcctgatatt aaattccctg atattaaatc
    21781 tctaatagct tttataaaag caactcctgg gagtagtggc attatagcgc cgactataag
    21841 cattttaggg tcatctaaaa tgcctatttc aactagtaga actcctgaaa gtgcaattaa
    21901 aaaagaagat actaaacagg aaaatgcaga tattgcactt atcttcatcg ttttatcata
    21961 agtaattgca gcaaagattg ctattataaa cgtaagtata aaatttaata cataattccc
    22021 tccaagcaaa caagcaaaac aagcagatgc aattcctgta caagagtaaa ataaccataa
    22081 aggataaggt tttacatctt ggatttcata aagacgtgca atggcattat caatatcata
    22141 ctctttgtca ctaacaaatt ctcgagaaaa actgtttaat aaagaaatct tatttaagtt
    22201 tatacctctt gattgaatcg ttttcataaa cgaaaagcca tcaaatttct catctgaaat
    22261 aattattact gtaggagttg taaaaatatt tacatgataa aaccctcttg acctgcatat
    22321 tctaaggaca ctgtcttcaa ccctagatgt ttcagctcca ttttttatca tcagttcccc
    22381 tacaaataga gctagtttta gaatattttt cttatattca agttcctcat tttgattcat
    22441 aaatacacct ccaaattaaa aaacgtaata ttgaaattat atcaaatttt taagtaatat
    22501 tccttaatat ctatacaaat atattatctt ttttttgttt caaaatagtc acatttaaat
    22561 tatatccaat taaaagaatt agacaatatt atttattata ttttaactta aaaataaaga
    22621 aagtaactat gttaaatatg gaaaaatggc aaaacacttg actattaatt ggtaaaggac
    22681 tataataata aattatcata ttgataaaaa cgaaaattat gaaatgtctg taaaaataaa
    22741 atttaaataa taactaggag gagtaatatg tttgagaact tgaaaaaagc ggaccctgag
    22801 atttatgaaa gtatgaaaag agagttaaaa agacaacaaa gaaatattga attaatagca
    22861 tctgaaaaca tagtatcagt tccagtaatg gaaactatgg gaagtcatct tacaaataag
    22921 tatgcagaag gttactcagg caaaagatat tatggtggat gtgaatacat agatgaagtt
    22981 gaaactcttg caatagatag aatcaaaaaa atatttggag cagaacatgc taatgttcaa
    23041 cctcattctg gagcaaatgc aaatattggt gtatattttg ctatgttaaa accaggtgat
    23101 gttgttatgg gaatgaattt atctcaaggt ggacatttaa ctcatggtgc tccagttaat
    23161 atttctggtc aatattataa attttatgaa tatggtatag ataaagacag tggacttata
    23221 gattttgatg aagttagaaa gatagcacat gaagtaaaac ctaaaatgat agttgcagga
    23281 gcaagtgcat atcctagaga aatagatttt aaaaagttta gagagatagc tgatgaggtt
    23341 ggagcattgc ttatggtaga tatggctcat atagcaggtc ttgtggctgc tggtcttcac
    23401 caaaatccat gtgaagtggc tgattttgtt acaacaacaa ctcacaaaac tttaagagga
    23461 cctcgtgggg gtgttattct ttgtaaagaa aaatatgcta aagacataga caaagcaata
    23521 ttccctggta ttcaaggtgg acctcttgaa catataattg cttctaaggc agtttgcttt
    23581 aaagaagctt taagtgatga gtttaaagaa tatcaggtac aagttgctaa aaatgcaaaa
    23641 gccttagctg aagaacttat taaaagagat tttaaattga tttctggagg tacagataat
    23701 catttaatac tattagattt gactaataaa aatataactg gtaaagcagc agaaaagaga
    23761 ttggatgatg cttatataac agctaataaa aatacaattc catttgaccc aaatggtgct
    23821 cttgttacaa gtggaataag acttggtact ccagctgtaa ctactagagg tatgaaagaa
    23881 gaagatatgg caataatcgc tgaggctata gacctatgtt taacttatga tgaagaatct
    23941 aaggctagaa cattggttgt tggtttaact gaaaaatatc ctttatatga agaatataat
    24001 attatggatt aattataaag aacaactaaa taaaatacat ttaaataatt acaatgattg
    24061 tgtatgtatt tgaatatatt tagatataaa aaaggtgtct caaaatgaac tttttagttt
    24121 atgaggcact tttttgtatg gaatcgaaca tatttgtatt atttaaataa taaaaaatat
    24181 ggttatctct atttttagat ggtctctttg tattttttaa ttaaaacttt aagatttctt
    24241 aagaattata ctaggttttt ctaaagattt aaagtctata cttataagta tagtaatcat
    24301 atgaaaagaa aagctttaac gaggagggaa tcttatgaag gtattaattc ttacaggaaa
    24361 atttggtatg ggtcattact cagcatcaaa ttctttaagt gaagatataa aagcaaaatt
    24421 tgataattca gaaataataa ttaaagatat atttgagtac attatgccta actattcaga
    24481 taaaatgtac aagacttttt ctattcttgt aaatcgggga agtagtcttt ataatttgtt
    24541 ttataaatgt gctgaaaatg gaaagaaaga tataaaattt actttttcag attatttttt
    24601 aaataaatta gatacattac ttcatgaagt acaaccaaca gtagttattt caacttttcc
    24661 attttgttct caattagtat caagatataa ggaaaaatat aactcaaatc ttcctttaat
    24721 aacatgtata actgatataa gtagtcactc agaatggatt agtaaaaata cagactgtta
    24781 tttagtagct agtaaatcta ctaaggaaga acttgttttt aaaggaatag atgaatctaa
    24841 gattaaagtt aatggtattc cagtaaaaaa agaatttaaa agaatagaac atgtaaatca
    24901 ttcaactaaa aaaaatattc ttataatggg tggaggatta ggattactgc ctaaatcaga
    24961 acaattttac aaagaattaa atagtttaga aggagtaaaa actactgtaa taactggtaa
    25021 taataaaaaa atgtactata aactatatgg tagatatgaa aatatagagg tagtaggtta
    25081 caccaatgaa gtatataaat atatgaaaga ttctgacctt attatttcta agccaggtgg
    25141 aataacacta tttgaaacaa tttattcaga acttccaata ttggcattta atccattttt
    25201 acaacaagag atagataatg ctagttttat attaaataat gaaattggga gaatacttgg
    25261 taaaaataaa aaatactatg tagatgagat aaaagattta atttatgatg atgctactct
    25321 taaagaaatg agcagtaaca tgaaagaatt aaaaaaacaa tttgataata ataccttaga
    25381 gaatatttta ttttcacttg atgaacaagg agcgtgtaga gaatgtatgt agtaggttta
    25441 attatcgttg ttgcattgat ttttttagtc cattcaatta tacctacata ctataataaa
    25501 ctattaaata aagaggtatt aaaaaatatg gctggagaaa atgaaattgc acttacattt
    25561 gatgatggtc cagataagag atatacagaa aaattactag atgtgttaaa agaaaatgat
    25621 atacaagcta tgttttttgt agtagcaaag aatgctgaaa aagagcctga aattataaaa
    25681 agaatgttga gagaaaatca tatagttggt ttacattcat tggaacacag aaatgcatgg
    25741 ctttatagtt atagttatgt taaaaaagat tttattgaaa gtacaaatat aatgaaaaat
    25801 ttaggtgtag atgtaaacta ctatcgtcca ccatggggtc atactaatat attttcaaat
    25861 tcatttgtta aaaaatataa tctaaaaatg actttgtggg atgtaatggc agaagattgg
    25921 gagaaagata gtacagtaga cattattata aacaagttaa tgagtagaac aaaagaaaat
    25981 tctataattt gtttacatga tgcaggtgaa aattcaggtg gtgcagtagg tgcacctgag
    26041 cgtactattg aagctttaaa gatagctatt ccaaaactta aagccagtgg tttaaagttc
    26101 gtaacaccag aaaggatgta gttatgataa gtaaaactga aaagaaaaat aaatgcctag
    26161 gtagtgtagc ttttttagtt ttactaatgg gcataacagg atattttgtt tttagagggc
    26221 agtcagttga atcattgata aaatcattaa aaggtgcaag ccctatgttt atactaattg
    26281 gatttgcaat gatgtttata tatgttgcct gtgaaggtat aaatatatac ttaggtatga
    26341 aagctttaaa ccaaaagact actcttttaa aatgtatggg atatgctttt attggatttt
    26401 attttagttc tattacgcct tcagcatcag gtggtcaacc agcacaagtt tattatatga
    26461 aaaaagacga tataaatata tcatattctt cacttatact attagtcatt gttgttattc
    26521 accaagtagt tatactggca tatagtggaa taatgttcat tatggaacgt gagtttatat
    26581 taaataatgt aagtggtatg aacattttac taatatatgg tgtaataaca aatgttgctc
    26641 ttgtcattgg agtaattgca attatatttt caaaaaaact tgtaaacaat tttataatat
    26701 caataacaaa tttattaggt aagttaagaa taataaaaga tgttgaaagt tcaagaaaag
    26761 ttataatatc tcaaattgaa gagtatgtta aaggtgctca atatataaag cagaatccaa
    26821 aacttgtagt ccaaatttta gtcataacta ttgtacaaat aacatctatg tttttagttc
    26881 ctttctttgt atacaaagct tttcatctat caacatatac tgtatttgag atattagcga
    26941 tacaatcctt gcttaatatt gctgtttctt cattaccatt gccaggggct gttggagctt
    27001 ctgaaaatag ttttatgaca ttatttaaga tatttttccc tggtcactta ttagttccgg
    27061 caatgttact tagtagggga ataagttttt atgcatttgt agctataagt ggattgatat
    27121 gtatagtagt acatgtaaaa tcttctgaaa aagtaaaagc agtgaaaaaa gttgcttatg
    27181 taagataata ttatatagat tatttttatt aatatgtcaa tttgtgtgta tattttaatt
    27241 aagctttaaa catgtttaca ggagtagaaa ctattaaaac gtgtgacatt gctaagcttt
    27301 tgctaataaa gtataatatt ttatatagtt tgaaatattt aagaaatata gcaaaaaaag
    27361 gagcttggtg atgaataaag agattccaaa aaaaatttta gtagctgatg ataatcctga
    27421 gattagggaa atcgtagaaa tacttttaac tggtgaaggt tatgaagtta ttatggcaac
    27481 gaatggagaa gaagctgtaa acttagtaga tagtacgatt gatttgatta ttttggatgt
    27541 tgtaatgcct gtaaaaacag gatttgttgc atgtaatgaa attagagaaa aaacgacagc
    27601 accaatatta tttttaactg caaaaactca agactctgat aaagttattg gattttcagc
    27661 aggaggagat gactatttat caaagccttt ttcatattct gaactaattt caagggttaa
    27721 gtcgctactt agacgttatt atatatacca gggaaaggaa aaggaaagag agccaaatat
    27781 attaaaaaca aaagagttat gtgtcaattt agatactcaa gatgttacac taaatggaga
    27841 acctgtgttt ttgacaacta tagaatatag tatattaatt cttatgttga aaaatagaaa
    27901 aaaagttttt tcgtctgaaa atttatatga aactatttgg gatgagcagt atttttatac
    27961 agcaaataat acaataatgg ttcatattag aaatttaaga aaaaagttag aaaaagacca
    28021 aaaaaatcca caatatataa aaaccgcatg gggaaagggg tattatattg attaacaaaa
    28081 ttaagccatc taagttggga gttatactat tgatatatgt agtaatctca gctgcagtgg
    28141 ctttcatttt aaatatacca ttttactctg ctgttgaatc tatagtaaaa gatgtatcag
    28201 aagggaaagt atattttaaa agagaagtaa atcaacttat ggataatttt caaacttatg
    28261 tgaataacaa tggtataaga gcagatgatg gagatgatat agcaaaatgg aatagtgata
    28321 attggtttgt ttctatgaag atatataaag gaaataaggt tttttatgat acattatact
    28381 atcctaatga agtacctgat aagagtgagg aaaatgagtt ttatagcagt cccatggcta
    28441 gaaactatga gatacaattt tctgatatta aagctaatat agttgtagta gctttattta
    28501 gatttagatt tcaaaatttt atagaagcaa tttctattac atttatggca cttacattta
    28561 ttataacatt tttactgttg tttagtagaa agataaagta cctaaggaaa atagaaatgg
    28621 gtataaagat agtagagagt ggcagtttaa agtatagaat cccagtaaaa ggtaatgatg
    28681 aattatcatc acttgcatct agtattaatg agatgagtca tacattggag aatcaactta
    28741 taaaagaaag ggagatgaag aataaaaata aagatatagt aacttcgata tcacatgatg
    28801 ttagaactcc attaacgtca gtaatttgtt atttagattt gattaaagac cataaataca
    28861 atagtcctga gcaattggaa caatacataa aaaatgtaag gtctaaagca tatcaaataa
    28921 aagatttaac agatgacctt tttacgcatt ttgttaattc tggagaggaa gtttcaaaag
    28981 ggtatgaaaa aataaatgct aatgaattta tttttcaatt acttttagat agttcatata
    29041 cattggagga gaaaggattt catataacaa tagaaaatga actttataac caatatcata
    29101 tttatgtaga tgttacacaa tttagaagga tatttgataa tttatgttct aatataataa
    29161 aatatgctag gaaagataag cctatagtat ttttaattaa agtagaggat tctaaattac
    29221 taattataca aaaaaataga gtaagtaatt tttctaagaa tgtagaaagt tttggaattg
    29281 gtataaagaa ttgtgagaaa atagttgcat atcataatgg aagcataaat gtaaattcag
    29341 atgataaaga atttgctatt gaaatatcta ttccagcaaa agaatcataa aaatttaaat
    29401 tatatattgt gtaattgcta ttatatattg tgtaattgct tatgtaaaat tctatgaagc
    29461 aggaagcatg tgactttagt tatgggatgt tcaatattgt gtacctctag gcaagtaaca
    29521 agtttactta caagaccata taatattatt atcttaaaaa aaggggacat aataatatgg
    29581 ttttgacagg agcacattat atttacattc tatttatggt aattatatta attactatga
    29641 ttatgaaaaa ggatacaata gtaccatgta tattaggtgt tttttttatg ggattgttct
    29701 ttgaaaaaaa catctttggt gctataacag cagtgtttaa ctcttttatt atatctttaa
    29761 atgagttggg tccaattatc ttgattatag ctattatggt tgcattatct aaagccctag
    29821 aagccaataa tgctatacag tatatggtga gaccattttc gagagttata aaaaattcta
    29881 atacagcatt ttttgtaact ggatttgtta tgttagttct ttcttggttt ttctggccaa
    29941 ctccagctgt tgccttagtt ggagctgtat ttttacctgt tgctatgaga gctgggctac
    30001 cagcaattgg tgttgcagta gcattaaatt tatttggtca tggtcttgcc ttatctacag
    30061 actttgttat tcaaggagct ccaagtataa cagctggtgc agcaggtgtt gcagtatcat
    30121 atgttataaa tgatggtatg attttgtttt gggtgatggg aatcgtaacc atatctatgg
    30181 cattttatac attaaaaaga gatattaaca aaggaatgtt tagagaagaa ctaaaaggtt
    30241 ttgaaagtga agaagtagaa gcgttcaatg gaaaatctaa aatagcaact attttagtag
    30301 ctttgggatt tcttgctgat ataattgcta tgtatgtatt tgacctaaaa ggaggagatg
    30361 catcagctct tttgggtgga acagcagtat ttttaataat aattataaat gttataaatt
    30421 ttggcaaaga tagtcttgaa aatgtatgtg agaatataat tgatggtttt gtgtttggga
    30481 taaaaatatt tggagcaatt ataccaatag cagcattttt ctatatgggt gaagttgcac
    30541 cattgacagg tgtatttgga aaagtattag caccaggttc acaaggttta ttatcagata
    30601 taggcatagc tctttctcaa acaataccac ttaataaatt tgccgtatca ggtatagaaa
    30661 ctgtagtggg agcaataact gggcttgatg gttctggatt ttctgggatt tcattagttg
    30721 gttcacttgc ctctgtattt ggaactgcta taaatgcaag tgttggtgca ttagctgcat
    30781 taggacaaat cagtggtata tgggtaggtg gaggctgtct agttccttgg ggtcttattt
    30841 cagcagcggc aatttgtggg gttagtccaa tagaattggc aaagcgaaac tttgtcccag
    30901 ttataaccgg attggttgta acaaccatag tagcaatgtt tattatttaa taaatcgaat
    30961 aaatctttaa ttgtataaat taaaaataga tgtgtagcta taatttatta taattgtttt
    31021 actaattcta agccatacat ctatttttat tgatattttt attagtattc tttaataaag
    31081 taatattttt cattatatta tacataacat ctaaatataa catctaaaat actgttatct
    31141 atatttaata tcttgccaaa ttttttgatg ttttattgcc ctgtcccacc aacatatata
    31201 agctatcaca agtttttacc tatactatca ccaaacaaaa attctaattt taatttatta
    31261 ttttataacc tatattatat taactatatt agtttgtaga ctttagatgt aattataaat
    31321 attaatactc caagagttca aattcatatc ctagttttct tgcatttgat ataaaatcat
    31381 ttaaaatttc tgtactagtt ttggaaactg catgtagtaa caagatagaa ccatcatgta
    31441 gattatccat tattttttgc gttgcttctt catgtgatgg ttgtttatca gtatcccagt
    31501 ctctgtatgc aaaactccaa aatacagtct tgtatcctaa atttttagtc attgccaagc
    31561 ttttttctga gtattttccc ataggaggtc taaaaaattt aaccatatct ttcccagtta
    31621 catctttata taacttttca acatcatata attcgtcatt aaagtttttt agattgcttg
    31681 tttttgttgg catagatgga tgggttttac tatgatttcc aactatatgt ccctcagaaa
    31741 ccattctttt tactaaatct ttattttctt ttatatatgg agctgtaaca aaaaaaactg
    31801 ctttaacctg gttttgtttt agagtgtcga gtatttttgt agtgtatcca ttttcataac
    31861 cttcatcaaa tgtaagatat agtgtttttt gaccatcttt tgtaggtcca ttgtataggg
    31921 catcatagtc agaaaattta aattcaatgt ccgtatttac ttctggtgtt ttatgcttat
    31981 tgtttggtat ataaaaccaa tcaagagtag tgttatctaa agaagataca tctaatttat
    32041 tattatcatt attagtagtg gcttttgatg gtttatctgt tccgtctgaa actattacat
    32101 tggaagtatc tttaccacta tctatttttt ccttatcttc ttgtaactgt gtttccttat
    32161 tttgattttc gttttgattg ttttgtgaat ttgaacatcc aacaataaaa aaaatagaaa
    32221 tagaaagtag tgttaaataa tgcaatactt ttctaaacat tttgaagctc ctttctaaat
    32281 taataataat tgcatataat aataattata tgattaatta caattgcata tagtattatt
    32341 ataattggaa attactatta ataatagtta tatctttaaa aataaagtca caatagtatg
    32401 acaaagggtg aataatcaat aaatttaaaa aaaaatgaaa aaaatagttg accatattat
    32461 gagaagatgt tattataata aatgtgctca acaagaagta acaaaataac aagcacaaag
    32521 aagttaattg aat
//
LOCUS       DAJMZY010000037        31852 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.037, whole genome shotgun sequence.
ACCESSION   DAJMZY010000037 DAJMZY010000000
VERSION     DAJMZY010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 31852)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31852)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31852
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.037"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            complement(102..362)
                     /locus_tag="OE968_001703"
     CDS             complement(102..362)
                     /locus_tag="OE968_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich small domain-containing protein"
                     /protein_id="HCP7218984.1"
                     /translation="MGENYKFFNHKDCEFFPCHKTNKPEEFNCLFCYCPLYALGENCG
                     GNFKYTDKGIKDCSSCILPHKKDNYNYIMSKFQDLVKITSKK"
     gene            579..1862
                     /gene="hflX"
                     /locus_tag="OE968_001704"
     CDS             579..1862
                     /gene="hflX"
                     /locus_tag="OE968_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HCP7218985.1"
                     /translation="MKEIQEKALLVGLNLTTIVKKNDDIDTNESMEELKELTKAAGAE
                     VVGSLIQNKHSVDAAYYIGKGKVEEIRAYSDSLDATLVIFNDELSGAQIRNIENVVGR
                     KVIDRTTLILDIFAQRALSKEGKLQVELAQLKYRLPRLYGMGGEMSRTGAGIGTRGPG
                     EQKLEIDKRHILNKAADIRRELKEVKKNRETQRVKRLKSNIPIVALVGYTNAGKSTLL
                     NELIKTHKDYEQEKEVFVKDMLFATLDVTLRKALLPNKKEFLVVDTVGFVSKLPHDLV
                     EAFKATLEEVQYADLILHVIDATNTSYELQKSTTEGVLKELGVNDKKHILVYNKVDKL
                     ELDIYPKSQEDIVYISAKQGINMDKLLNMIEIALMENTYSVSLMLPYERGDIFSRIKD
                     KYNVENFEYGESGITLDVDLDEEDFNIYREYILEK"
     gene            1870..2547
                     /locus_tag="OE968_001705"
     CDS             1870..2547
                     /locus_tag="OE968_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HEAT repeat domain-containing protein"
                     /protein_id="HCP7218986.1"
                     /translation="MDINWENIDNLEDYFITYLLYKESKTVSQISKIRNISSTEASEQ
                     LIQAKLKIKEMQKDDFEASKDILDKFLELDKIKRLDFMDSLDDEKMVYFKRKVFKRIL
                     VEKNAEDLIVLIWATGELKDDRFLKLLHQLTNHRHSDIRRITYSAIRKIESPSSREVL
                     QKGLYDKNAQTRQYCAKALSKLGDENSLKILQQLKDKNKNFEKEYVLRAYDKAIKSLE
                     NAKNLKK"
     gene            2633..3076
                     /locus_tag="OE968_001706"
     CDS             2633..3076
                     /locus_tag="OE968_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HCP7218987.1"
                     /translation="MIVRRCAGGVVFYANKVLIVKNDRGEWTLPKGKILGGGLPYESA
                     VQRVKVETGIDAKMIDVAGDTMYEFFSRSRQQEVCNAIMWYVMEACNTDCVLAPEFQE
                     GGFYKVKDALEMLSHHKEQALVEVSYKKFKELKKLVSEGDDVPAN"
     gene            3381..4025
                     /locus_tag="OE968_001707"
     CDS             3381..4025
                     /locus_tag="OE968_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HCP7218988.1"
                     /translation="MSNYRTLHEFGMDEITIEKSVFIGYAKPIKSEEEALEFINEIKK
                     KHKDATHNVWAYTVGKNMNIQRYSDDGEPQGTAGIPTLEVIKKEDLRDVAVVVTRYFG
                     GTKLGAGGLVRAYTKGAKLGLEAGKIIYKVMYQEVKVKIDYTQLGKVQNELMNLGYFI
                     KDTVYEDNVEIVVYSRLEDVEKLSEKMIDITSGTGKIVLGEEFYLSEQNGEILI"
     gene            complement(4111..4488)
                     /locus_tag="OE968_001708"
     CDS             complement(4111..4488)
                     /locus_tag="OE968_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HCP7218989.1"
                     /translation="MLFALIGFFAGIIGGMGMGGGTILIPALVLLAGIDTKIAQSVNL
                     LSSIPMTLIALAIHIKNKNVIFKLVIPIAVFGVLGAVFGSLLANYLSSDILKKIFGIF
                     LLLVGLFEVKKGFCAKSDKKPLN"
     gene            complement(4488..4874)
                     /locus_tag="OE968_001709"
     CDS             complement(4488..4874)
                     /locus_tag="OE968_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HCP7218990.1"
                     /translation="MKKTDDLKKKYFDFNLKNTIIGVFTGFINGVFGSGGGTLLVPIL
                     NDIVKVEEHKSHATALSIIIFLTTASSVLYVSKGTYDVNLTIKVAVGSILGGIIGAKL
                     LNKVTGKFLRISFGIIMIIAALRMVF"
     gene            5053..5808
                     /gene="nadE"
                     /locus_tag="OE968_001710"
     CDS             5053..5808
                     /gene="nadE"
                     /locus_tag="OE968_001710"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(+) synthase"
                     /protein_id="HCP7218991.1"
                     /translation="MSNIKIQIDKTVEWLINKVNEANAKGLIVGVSGGIDSAVVANLI
                     KKAFPENSMGVIMSIKSNPQDREDALKVIEGCDIEYLDLDLIEPQSAILDMVVGNLKD
                     KHLYREEYLKMTDANLRARVRMSTIYTIANNLGYLVVGTDNAAEIHTGYFTKFGDGGV
                     DILPIANLTKGEVYEWAKELGVHEDLINKAPSAGLWEGQTDEDEMGTTYNMIDAVLEG
                     RLDEVPKRDQEIIERLHRLSEHKRKTPAQPPKF"
     gene            5891..6610
                     /locus_tag="OE968_001711"
     CDS             5891..6610
                     /locus_tag="OE968_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCP7218992.1"
                     /translation="MGRIGNIINRKGKQDAQRAKIFTKHARAIAVAAKEGGADPEYNA
                     ALKTAIEKAKADNMPNDNIDRAIAKGAGAGAGEDYETIVYEGYGPGGVAVIVETLTDN
                     KNRTAGNVRYYFDKNGGNLGTSGCVSFMFDKKGQILVGLGDGVSEEELMDVALEAGAE
                     DFITEEDGYEIITTPEDFSSVRDELKAKGYEFISADVKMIPQTTTVLTEESHLKMMNK
                     LVDMLEEDDDVQDIYHNWEVE"
     gene            complement(6777..7781)
                     /locus_tag="OE968_001712"
     CDS             complement(6777..7781)
                     /locus_tag="OE968_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HCP7218993.1"
                     /translation="MATIKDIAKDCGLSSATVSYVLSGKGNERRIPLHTQELILNSAD
                     KLGYKRSTPIKHNNIKIAFYWQDEGFELASTNILQAINHIISLEHLNINIIIRPYKVG
                     HLCDDEYFFANNYYDGIVLTGINADDIEYLVKNKPKIPVVVVNREIPGFSSVSIDNEE
                     TGRIAALHAIQNGKNDIAVVFNPTSFTCMTLRGKSFLKTCKEHGIHLSDSIYYCSNKI
                     DSGYDIAQKMLAKNSLKKVIFCNHDVVALGMMNAFHESGIVIGEDIQIFAASNGPSRL
                     MARSIPPLTVIDLKMEETAERSLRMIIDTVTGRINGIQQQVIYPSIIYRQSSPAQNLL
                     "
     gene            8047..8943
                     /locus_tag="OE968_001713"
     CDS             8047..8943
                     /locus_tag="OE968_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA lyase"
                     /protein_id="HCP7218994.1"
                     /translation="MSKVNIFEVGPRDGFQNLKEFLETDKKLKIIDGLIASGIKQLEI
                     SSFVSPKAIPQMKDAKEVATYCVEKYPDVKLYALVPNLYGAKVAWECGIRDISYVISL
                     SETHNKKNINRTHEESIDELKKIMNTYPDMNICIGMATVFGCPFEGLPKIEDAIRFAK
                     RLWENGIREMNLADTIGIADPKQVRETISALVEALPECRWQVHIHDTRNMGMVNTLVA
                     IESGITTVQSTLGGLGGCPFAPGASGNTATEDLVYMLERMGYDTGVDFVKLLELSKYQ
                     KSFVNGVYSGHHVNIKSDSCNC"
     gene            9081..10343
                     /locus_tag="OE968_001714"
     CDS             9081..10343
                     /locus_tag="OE968_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7218995.1"
                     /translation="MDIIALLLFLGVIIIAFVRKNNAGILALAIGVIAVRIFGMDDKE
                     LYGAISNSMFTTLVGITLLFAIVNSTGALKLVAEKIVAASGKRVWLIPIAVFIAGFVV
                     AGVGPGAIPALAIIPAMAVPVAITVGYNPVMLALIGECGLMAGRMTPITPEGQIITTV
                     AEGVGIENVMPTILACQTLSTIVFSIVLFIIFKGYKLKKPINVIDSKQIEKFNIKQII
                     SLISIVVMIAFIIIFDMNVGLAAFAVSAVLIFFNIADEGECIKSIPWSTIVMVLGVGA
                     MMTIVDAAGGIDLMSNALSSLMNSKTATPIMSISAGLMSMVSSALAVVYPTMMPMCVD
                     IAKAVGGVDPLALIAAVGVGGSLAGVSPLSTGGALILAAMGSSKKDFNKEEQNKVFVQ
                     LFIMSAVGLLVIAVVSILSFNAITHLMN"
     gene            10419..11612
                     /locus_tag="OE968_001715"
     CDS             10419..11612
                     /locus_tag="OE968_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase"
                     /protein_id="HCP7218996.1"
                     /translation="MKKGALSNIKVLDLTRVLAGPYCTMMLADFGADVIKIEMPRKGD
                     DTRGFGPFVNGESLYYANINRNKKGITLNLKSEEGKNIFLEMVKHADVVVENYRPGVM
                     EKLGLGYDELAKVNNQIIYGAVSGFGCYGPYSERPGYDIIAQAMGGLMSITGQEGGEP
                     TRVGNAMGDVLGGMNLTIGILTALNARKIIGKGQRVDVSLVDSVVSSLETGIQRYFDS
                     GQPELMGNRYASAYPYDSFKASDGSFVIGCGNDKLFEKLCKKVLFREDLLIDERFKTN
                     LNRCEHYKALKPEIEKWSIKHTIKEAVDLISEAGVPAAPIYNLDCVTTDEHIAKAREM
                     IVDISHPIIGNMKVNGNPVKLMTTKAKIDMPAPSLGESNEEIYNGWLGFDSDKIKDLK
                     ENGVI"
     gene            12241..13035
                     /locus_tag="OE968_001716"
     CDS             12241..13035
                     /locus_tag="OE968_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase/isomerase family protein"
                     /protein_id="HCP7218997.1"
                     /translation="MESVMENLNNLKVEVKDKVCVITINRPKALNALNSDTLRELSQV
                     IDVVSENEAILGVIITGEGKVFVAGADIRQMQNYKSEEGRKYAGYAQGVFDKIEALEK
                     TVIAAVNGYALGGGCELAMSCDIRIASEKAIFGQPEVNLGVIPCFGGTQRLSRLVGTG
                     IAKELIFTGRQVNAEEAKSIGLINKVVPSDLLLEESMKMMNQIVEKAPIAIRYAKVVI
                     NKGIDMDLKNALELEKDIAGLTFATRDKQEGMNAFIEKRKPVFENK"
     gene            13130..14470
                     /locus_tag="OE968_001717"
     CDS             13130..14470
                     /locus_tag="OE968_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HCP7218998.1"
                     /translation="MNTGVIISLVGIIIALSLLVVMVMKGINIFIIAIVCSSLVAITG
                     SLNVYDALKVDYMTGFVGFLQANFFIFLTGTLMGKIMEITGGAKSIAKMIVRWIGKDK
                     ALLSIPIACGILAYGGVSVFVVSFAVFPIALEIFKEADLPRRFIPAALTFGCSTFAMV
                     APGAPQIQNIVPASTLGTDIMAGAVNGFISCAVMFIVGSTILYKMVSKEKANGGHFIA
                     HESDIFDEAEATNSKRENGPNGVIALIPLIVSILIINVKVNGKAIVPIEVGVFIGALL
                     VYLLLNKYQDNTKIVGHVGDACKTTVVAICNTCAVVAFGSVVKSAVGFDFIVNAMTNI
                     PGPPIAGAAVGTTVIAGICGSASGGLGIAAPLLGPVFLAKGVSAAALTRTMAISSAAL
                     DSLPHNGYIVTVTNGLCKETHKDAYMPIFWVTVLTPFIGTIVAVLLFTMFPGLP"
     gene            14607..15839
                     /locus_tag="OE968_001718"
     CDS             14607..15839
                     /locus_tag="OE968_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase"
                     /protein_id="HCP7218999.1"
                     /translation="MLNKPLEGVKVIDLTYFVAGPGTSKILADWGADVIKVEPSFGDP
                     GRKTGATMTMPIDDYNNPFYSTYNSNKRGLSINLKSETGIEIMDKLLSEANVFVSSYR
                     TGALKRLGLDYESLSKKHPHLIWGQINGFGDFGPAKDNAGFDTVAFWARSGAMLDIAE
                     KDTSPINPPIAFGDATTSCSLSGGICAALYQQAKTGKGQKVMASLFGQAIWNASSLLA
                     STQFSDEYPKTRKNAISPVINSYRCKDGKWIFLSILEHERYFEALCRLFGREDLIKEE
                     KFASSVESKKNATELINILDGEFAKFTQNEMVEKLTAADIAHEKIQHVNDVVTDEQAI
                     ANNYIYEHTSKDGNKTMLASTPVKFGNIEVNMTCDAPLIGEHSDEILRELGYSDSDIE
                     ALIESGIVTMNKEACEIC"
     gene            15879..17021
                     /locus_tag="OE968_001719"
     CDS             15879..17021
                     /locus_tag="OE968_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="HCP7219000.1"
                     /translation="MDFRLTEAQLMLQRVAKEFAENEIAPIAAETDKTGIFPRELFSK
                     MAKIGFNGIGTPVEYSGSGGADIEKVIVVTEIAKKCAASAAILSIHTIYAQAILKFGT
                     EEQKKKYLPMMAEGGCVGAFALTEPNAGSDAARAATTAIIDEETDEYVLNGTKCFISG
                     GGQAESLIIFALTDPSKGIKGMSAIIVDKGTPGFSIGKIEEKMGIHGSETAELIFDNC
                     RVPKSNLLGKEGKGFNIAMTCLDGARIGVGAQAVGIAEGALEESIKYSKERVQFGKPI
                     SALQGIQWYIADMATMVESAKLLVYYAADLKARGEKHTKEAAMAKYNASRTAREVTNL
                     ALQIHGGYGYMKDYPLERMYRDAKITEIYEGTSEIHKVVISRAVLG"
     gene            17032..17826
                     /locus_tag="OE968_001720"
     CDS             17032..17826
                     /locus_tag="OE968_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HCP7219001.1"
                     /translation="MNIVVCLKQVPDTNEVKINKETGTLIRDGVPSIINPDDRNALEE
                     ALKMKDELGAVIKVISMGPPQAKSALKEALAMGADEAYLISDRAFGGSDTWATSTIIA
                     AAIEKVGKYDVIFCGRQAIDGDTAQVGPEVAEFLGIPQVTYAKEVKVQDDKLLVTRYT
                     ETGDYLIEAKMPVLLTAIKELNNPRYPSVKGILEAYNNGDAKITVLTLADLDVDTTQI
                     GLKGSPTNVYKSFVPVKDKHNEIIEGINKKEKAEKLIEILFDLKLV"
     gene            17837..18859
                     /locus_tag="OE968_001721"
     CDS             17837..18859
                     /locus_tag="OE968_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HCP7219002.1"
                     /translation="MMRAKVNQGINLNDYNGVWVIGEQREGKINPVTIELIGEGRKLA
                     DQLGKELAVVIAGYEVEKEVKELLHYSVDKVYYINDPLLKDFTTDGYAISIANLIERK
                     KPEVVLVGATSIGRDIAPRIAGKVGTGLTADCTKLEIDSTDNKLLQTRPAFGGNLMAT
                     IVCPKNRPQMSTVRPGVMAKAVRNESETGILEVVTPELTEKMIRTRLVEILPQEKKSV
                     NLTDARIIVSGGRGLKRAEGFELIKELADKLGAEIGASRAAVDSGWIEHSHQVGQTGT
                     TVRPELYIACGISGAIQHLAGMSDSKYIVAINKDAKAPIFSICDYGIVGDLYEIIPEM
                     IESLNR"
     gene            18958..20334
                     /locus_tag="OE968_001722"
     CDS             18958..20334
                     /locus_tag="OE968_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54-dependent Fis family transcriptional
                     regulator"
                     /protein_id="HCP7219003.1"
                     /translation="MKEQWYKDIFARVLSMTDDGFIVVNRSGVIIDINDKYCDFLGKE
                     RKDIIGQNIQSIIPNTKMLDVMKNKYCEEGAIHHYSGGNTKEKSVIVSRSYVENDNGE
                     VVAGVAQVKFRLQSFDVAKKLMSEYMELQYYKEQFKDNCGFDKLIGENRDFIELKKTG
                     VKASKTNFPVLLTGETGTGKEVFARAIHNNSSRSDKPMVSINCAAIPEELLESELFGY
                     DEGAFTGAKKGGKKGKFLVANNGTIFLDEIGDMPLTMQAKLLRVLQESEIEPVGGLKT
                     IKIDVRVISATRKNLSKMVEEGLFREDLYYRLNVINIHMMELKDRQDDILLLANYILN
                     KLNVEYKELKVLSDKVKNCFINYTWPGNIRELQNVIKSAYAVSDDMVIMMCDLPSKMD
                     NISRVAQCNVDSNCSIHEMVENYEKSLIIDVLRKYNWKCSKAAEVMGIHKSLLYKKIK
                     KYEIELNN"
     gene            complement(20666..21010)
                     /locus_tag="OE968_001723"
     CDS             complement(20666..21010)
                     /locus_tag="OE968_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219004.1"
                     /translation="MDQIKRLHELQQKSYLTKEEFEELKNNTYIERFELRDECDNSYI
                     YTFYTNDKCNDIKFIKSQFIVTLIKIGFLCECGGVFRQKKIVDEYDYGYNAIYKCDSC
                     GKELDKEVENYD"
     gene            21498..22508
                     /locus_tag="OE968_001724"
     CDS             21498..22508
                     /locus_tag="OE968_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4116 domain-containing protein"
                     /protein_id="HCP7219005.1"
                     /translation="MHEDKNDIFESIDTEDFDNKTEEECLELVRKNGLNLIYIKNQTE
                     EICLEAVRQNCNAIKCVQNQTEKICIEAVKQDWRMLEFVEEPTEEICMLAINQDGTAL
                     KYIENQTEELCLRAVEKNGAALEYVKEQTEEICIEAVRNSEFGLARVKNQTEKICMEA
                     VKHCSYNLKWVENQTEEICMEAVRQNGLDLKFVKNQTETICLRAVRQNGMALEFVKEQ
                     TVGICLKAVRQYGMALKFVKEQTEEICTEAIKQDKRALSFVKGDKEKYKALYDNNEPF
                     AKRYVRNVIEKENRALIKKGEENAKIKIAGKLYDRGMSFEDISDIVEIEISKLKVSLG
                     VF"
     gene            22619..23107
                     /locus_tag="OE968_001725"
     CDS             22619..23107
                     /locus_tag="OE968_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HCP7219006.1"
                     /translation="MKITVLYQTRSGNTERVAKLIEEGAKKVDGVDVKLMRLDNIDLD
                     YLNESKAVIFGTPTYLANTTWEVKKWFDEDSKKVNLAGKLGAVFATCDYICGGPDVAI
                     LTIVGHLMVKGMLVYSGGGSLGKPFIHLGHVHSIEGPELQDEKAIIFGERIATKAKEL
                     FA"
     gene            23283..25211
                     /locus_tag="OE968_001726"
     CDS             23283..25211
                     /locus_tag="OE968_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HCP7219007.1"
                     /translation="MVWHIEYEIFSAIIVIFLMVYFFRSKFIPTLQNKIYCALLIFSF
                     LFIISNILGSFCLNNIDKIPIFITFLLNQIYLLLLPIPAALVSFYVMAIIYQDIRYMK
                     KRLLFLSIPLIICIILSITNPFTHILFGLSKETGYIRGCGYVATFASFFFYAIYSAFL
                     SFKYRKAMHESKIWAIRGFLIVSIVAIILQAIFLQYLLTGTACACSLLLTYLSMQNRG
                     LIIDDLTGVLNRQSFIQELDLNINTEQSGFIITIALDDFKFMNETFGTKNGDIALKEV
                     GKYLIQIHDVNHVYRIGGDIFSIVVNSQLGIEPDDIIRKIEERFKKPWLVEEISFNLA
                     TSIAVVYYPENAETTEDVIVAIDFSIHEAKRSESRRVVYADASISEKIKKKHVIKNCL
                     KEALKNDGFEVYYQPIFSNSRGRFTSAEALLRLEHKELGFIPPDEFIPIAEQTGLINS
                     IGLVVFEKVCRFIASDEFEDLKLDNIAVNLSVVQCMQKNLADDLLYLMNKYNVSPTKF
                     KLEITETVAMGSFNIIKETMERLIDLGVKFALDDFGIAYSGVTNMLSLPFSVIKLDKS
                     LIWSMNEDSRHKLTVETIIALINKLNMKAVAEGVETIKCAEDLIAMECEYLQGYYFSK
                     PVPEDVFKNLLKENTFTS"
     gene            25388..25798
                     /locus_tag="OE968_001727"
     CDS             25388..25798
                     /locus_tag="OE968_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HCP7219008.1"
                     /translation="MNKKKILVPIDGTERSMHSLEFIKGIFKKDEVEVEIMNVKELVF
                     IDGISLAEEIKNSENLGRRILDKAAEIMGEYDVKVHFTFGYPGDEIIRKAKEDNVDFI
                     VMTKSTKKGLTRMIGSVTASVVKQAKCIVMIVPE"
     gene            25820..26122
                     /locus_tag="OE968_001728"
     CDS             25820..26122
                     /locus_tag="OE968_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIBC"
                     /protein_id="HCP7219009.1"
                     /translation="MNKKIVAVCESERSLNSLKTAANDLGFDLVYEIQENDNIKNELS
                     IYDIEDASIVLFVTSDSIESIEKIDRFIDREFYEVDPKYIIEDAKSIVSEILIDLN"
     gene            complement(26339..27031)
                     /locus_tag="OE968_001729"
     CDS             complement(26339..27031)
                     /locus_tag="OE968_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HCP7219010.1"
                     /translation="MKSLNATEKIIDYIKLNILNGTFKINSKLPSERKIADLFNISRI
                     PVRNAINILCKEGILRAVPYSSPIVEGFKKVDLFDDGEIYKNHNIQEFYVESLRARQL
                     IESEATKLAILNATSKELQKIKYTYLKSIEELDKVSHGLIEECYDADLQFHKEIILAS
                     HNPIFIKYYELIPKTVSSNQYFGFKYRNSLKDMISHHNKIMIAFDSKDSYLGYTSMYN
                     HLEDVIQLFQHD"
     gene            complement(27057..28244)
                     /locus_tag="OE968_001730"
     CDS             complement(27057..28244)
                     /locus_tag="OE968_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCP7219011.1"
                     /translation="MKKISNQKLLLLSIVTFFWFSQYVYIPFQNPYLSACNVSTNMIG
                     IIIGAYGISQCLLRLPVGVFADSINKHKIFILSGIFFAGLASLIRVFSPGGNGFLIAN
                     ILSGISSSTWISYMVHYTNFFSTEHQQKATSTIILVNNLGMLIGFVMSTLFYEKLGMT
                     ALCIMSVLSSVIGTILALNIKNHNSKKIPEKISIKKYLSICKDKRLVFFSFMALIQQG
                     IQMSTTMSFTTQILKNLGSSSTLIGLSSIFYMVCAVASSGFASTKFCTKYGPKFWIPL
                     VFILVSAYCFLVPTIKNINIIFVLQVLPGISTGILLSYLTSESMKNVPKHQKSTAMGF
                     FQAIYAIGMSVFPMIVGKISEYTSIQYGYFILAIIAILASILSYTYYKKVDLTLNYDI
                     IQS"
     gene            28580..30457
                     /locus_tag="OE968_001731"
     CDS             28580..30457
                     /locus_tag="OE968_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HCP7219012.1"
                     /translation="MDYKNIAQEILLNVGGKENVNEVTHCMTRLRFKVKSASKVNKDK
                     LSKTEGVITVVESMGQIQVVIGNKVKKVYDEVIKIVPQSNNVGKKNESQEKQGIINSI
                     LSAVAGIFTPTIPAIAGVGMIKGILSVLAMYYMNKNGVDIKETQSYIILNALADSIFY
                     FMPIILGYTAAKVFNANKIISMVLGATLCYPTFTALMAGEESVRFLGLAVTKATYTSS
                     VIPIIIAIWALSYVEKVLEKYIPEVIKIIMVPTLSLVVMLPATLFLFGPIGIYIGNVI
                     NFSYKYIYELSPALCGAFVGGLWCVLVIFGAHRALLPIGISDVAQTGRQNLLAFAGAA
                     NFSQAGAALGVFFKTKNQGLKTISMSATITALFGITEPAIYGANLRLKKPMVCAVICG
                     AFGGAIMGMGGAYGNAFANQGVLTIPVYAEAGALGFLSYLGGCAIAFFGSAISTYLVG
                     FEDLEESSNKENSSIKVETKDGVIDITSPVEGECIELSEVKDDVFASKAMGEGIAVLP
                     TKGVITAPTDCEVASLFPTLHAIGLKLDNGAEMLIHVGINTVELNGKYFTKHVNQGDL
                     VKKGDKLISFDIDKIKKVGYDVTTPVIVNNTFDFGQVVSCKSSYVSTNDNIISLVLAG
                     N"
     gene            30767..>31852
                     /locus_tag="OE968_001732"
     CDS             30767..>31852
                     /locus_tag="OE968_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HCP7219013.1"
                     /translation="MNTGFPKDFLWGASSSAFQVEGAWDKDNKGKTVADYNSFKKSHL
                     QADTKVASDFYHNYEEDIELMKELGMKTYRFSISWARIIPDGEGEINQKGLDFYNKII
                     DKLIECDIEPFVTLYHFDLPFKLVEKYNGWESRETVYAFERFAKICFKHFGDRVKYWQ
                     PHNEQNLIVRVEERINIYDETDSWKIDKMRAQMDYNLCLAHALAVNACHEMIKESKIG
                     AAVSSSVTYPLTSKPEDIYAARMNDNFKVYYMLDMHHYGEYPGYYMKYLEKRNIVPHM
                     EDGDKEILKKAKMDFIAVNYYRTNCAEALPEDSQHPFGLREGTVDFSMYGLFKMSMNP
                     NLEASEYGAAIDPSGLRVALNEYWQRYH"
BASE COUNT        12037 a         3656 c         5970 g        10189 t
ORIGIN      
        1 aggattagat taaaagttat acaataaaaa tagctgtgca ataatattta gactatgaaa
       61 gtagttaaaa aatatttatg cacagctatt tataatagaa tttacttttt actagtgatt
      121 ttaactaaat cttgaaattt actcataatg taattgtaat tatctttttt atgaggtaat
      181 atacaactac tgcaatcttt gataccttta tctgtatact taaagtttcc accacagttt
      241 tctcctaaag catacaaagg acaatagcaa aatagacagt taaactcttc tggtttatta
      301 gttttatgac aagggaaaaa ttcgcaatct ttgtgattaa aaaacttata attttcgccc
      361 atattttcct cctaattaaa taaaatttaa attttttata ctatataaga ttttggtgat
      421 aatataatta tactaaataa ttttatgaat agtcgataat atagtattat taatcatagt
      481 attaatggta taattagtca acagaaaaat aatgtaaaaa taatgtaagt gtattttgta
      541 attagaatat gttttataac aaaaaatgag gtgattaagt gaaagaaatt caagaaaaag
      601 cacttcttgt aggtctgaat ttgactacaa tagtgaaaaa aaatgatgat atagacacta
      661 atgaatctat ggaagaatta aaagaactaa caaaagctgc tggggcagaa gttgtaggta
      721 gcttaattca aaataaacac tctgtagatg cagcttatta tataggaaaa ggtaaagtag
      781 aagaaataag agcctatagt gactctttag atgctacttt agtaattttt aatgatgaat
      841 tatctggtgc tcaaatcaga aatatagaga atgttgttgg aagaaaagta atagatagaa
      901 ctactttaat tttagatata tttgctcaaa gggcacttag caaagaaggt aaattacaag
      961 ttgaattagc acaattaaag tatagattgc cacgacttta tggaatgggt ggtgagatga
     1021 gtagaacagg tgcagggatt ggtactagag gtcctggaga acaaaaacta gaaatagata
     1081 agagacatat acttaataaa gcagcagata taagacgtga acttaaagaa gtaaaaaaga
     1141 atagagagac acagagagtt aagcgtttaa agtcaaatat accgattgta gcacttgttg
     1201 ggtatacaaa tgcaggaaaa tctaccctgt tgaacgaatt aataaagaca cacaaggatt
     1261 atgaacaaga aaaagaagtt tttgtaaaag atatgctttt tgcaacttta gatgtaacct
     1321 tgagaaaggc tcttttgccg aataaaaaag aatttttagt agtagatact gttggatttg
     1381 taagtaaact tccccatgat ttagtagaag cgtttaaggc aacattggaa gaagtacagt
     1441 atgcagattt aatcttacat gtaattgatg caacaaatac tagttatgaa ttgcaaaaaa
     1501 gtacgactga aggtgtatta aaagaacttg gtgtaaatga taaaaaacat atacttgtat
     1561 ataataaagt ggacaagcta gaattggata tatatcctaa aagtcaagaa gatattgtgt
     1621 atatttctgc aaaacaaggc ataaatatgg ataagttatt aaatatgata gaaattgctt
     1681 taatggaaaa tacttattca gtaagtttga tgttacctta tgagagaggt gatatattta
     1741 gtagaataaa agataaatat aatgtggaga attttgagta tggggaaagt ggtataacgc
     1801 tagatgtaga tttagatgaa gaagatttta atatctatag agagtacata ctagaaaaat
     1861 aggttgaata tggatataaa ctgggaaaat atagataatc ttgaagatta ttttataacc
     1921 tatcttcttt ataaagaatc taaaacagta tctcaaatta gtaaaattag aaatatttca
     1981 agtactgaag caagtgagca acttatacaa gcaaagttaa aaataaagga aatgcaaaaa
     2041 gatgattttg aggcatctaa ggatattttg gataaatttc tagaactaga taaaattaag
     2101 agacttgatt ttatggatag cttagatgac gaaaaaatgg tatactttaa gagaaaggtt
     2161 ttcaaaagaa tccttgtaga aaaaaatgct gaagatttaa ttgttttaat ttgggcgaca
     2221 ggtgagctaa aagatgatag gtttttgaaa ttgcttcatc agctcacaaa ccacagacac
     2281 tcagatatta gaagaataac ttattcagca atcagaaaga ttgaatcacc aagtagtaga
     2341 gaagtactgc aaaaaggtct ctacgacaaa aatgcacaga ctaggcagta ctgtgcaaaa
     2401 gctctttcaa aattgggaga tgaaaacagt ttaaagattt tacagcagtt gaaagacaag
     2461 aataagaatt ttgaaaaaga atatgtgctt agagcttatg acaaagccat taagtcattg
     2521 gaaaatgcaa aaaatttgaa aaagtaattt tttattaaag caatttgttt acttaatgat
     2581 gtatttctaa agtttaacaa ggtaataaat aaattaatgg gaggggtttc aaatgatagt
     2641 aagacgttgt gcaggtggag tagtgtttta tgctaataaa gtacttattg taaaaaatga
     2701 taggggtgaa tggacacttc caaaaggaaa gatactagga gggggacttc catatgagag
     2761 tgctgttcaa agagttaaag tagaaactgg catagatgct aaaatgatag atgtggctgg
     2821 cgatactatg tatgaatttt tctcaagaag tagacaacaa gaagtttgta atgcaataat
     2881 gtggtatgtt atggaagctt gtaacactga ttgtgtactt gctcctgaat ttcaagaagg
     2941 tggattttat aaagtaaagg atgctttaga aatgttatca catcataaag agcaagcttt
     3001 agtagaagta tcttataaaa agtttaagga attaaagaaa ttagtttcag agggcgatga
     3061 tgttccagca aattaattgt gaatttagag gattctgagg aagggatagc cccttccttt
     3121 tttaattgaa gcagttttaa gcgtaaatta tatagtctct ttaaactatg atttatcaat
     3181 ttagagattt agtagtttat atttaaaatc agtaagatat atttaaaata aaaattaaaa
     3241 agtatacaat tttattatat aattgtctta tgatgttgat taaagaatta ttaaaagtcc
     3301 atttattttt aaatagaata attttataaa tatatatttg atgtgtatat tagaaaatga
     3361 ttaaaatagg aggaaataca atgagcaatt acaggacatt acatgaattt ggaatggatg
     3421 aaataacgat tgaaaagtct gtttttattg gatatgctaa gcctataaag agtgaagaag
     3481 aagcattaga gtttataaat gaaataaaga aaaagcataa agatgcaact cacaatgtgt
     3541 gggcttatac tgtaggtaaa aatatgaata tacaaagata tagtgatgat ggagaaccac
     3601 aaggaacagc tgggatacct acattagagg ttataaaaaa agaagatttg agagatgtag
     3661 cggttgttgt tactaggtat tttggaggaa caaaattagg tgcaggtggt ctagttagag
     3721 cttatacaaa aggtgctaaa ctgggacttg aagcaggtaa gataatttat aaggtaatgt
     3781 atcaagaagt taaggttaag atagattata ctcaacttgg aaaagtgcaa aatgagttaa
     3841 tgaatttggg gtattttata aaagatactg tatatgagga taatgttgaa atagtagtat
     3901 attcaagatt agaagatgta gagaaattat cagaaaaaat gattgatata acaagtggaa
     3961 caggaaaaat agttttagga gaggaatttt atttgtctga acaaaatgga gaaattttaa
     4021 tataatctaa aaggttatta gaatagttaa tacctcaaat agccaattag tatttttaag
     4081 tgaaaagcca ttaaattgat ttaatctaaa tcaatttaat ggctttttat cggattttgc
     4141 acagaatcct ttttttactt caaataaacc gactaaaagt aaaaatatcc caaatatttt
     4201 ttttaatata tctgaagaca gataattagc taatagtgaa ccaaatacag ctcctaaaac
     4261 cccaaacaca gctataggta taaccaattt aaaaattaca tttttatttt ttatatgtat
     4321 agcaagtgct ataagtgtca tagggataga tgaaagtaaa tttacgcttt gtgctatttt
     4381 agtgtctatg ccagcaagta aaacgagtgc aggtataagg attgttcctc cacccattcc
     4441 cattcctcca ataattcctg caaaaaatcc aattagagca aataacatta aaacaccatc
     4501 cttaatgctg caattatcat aattattcca aaagaaattc taagaaactt tccagtaacc
     4561 ttatttagta atttagctcc tataatacca ccaagaatac ttccaactgc aactttaatt
     4621 gttaagttaa catcataagt acctttagat acatataaaa cagaacttgc tgtcgttaag
     4681 aatattatta tagaaagagc agttgcatga gatttatgtt cttctacctt aacgatgtca
     4741 tttaatattg gaactaaaag agtacctcct ccagaaccaa aaactccatt tataaatcct
     4801 gtaaaaactc caattatcgt attttttaag ttaaaatcaa agtatttttt ctttaaatca
     4861 tcagtttttt tcataaaaat caccttctga aatagtttta ccaaaatagg caaattatat
     4921 ttatataaaa taagattaaa tataatcttt catgtttgtt taattttgca taaaaaaaaa
     4981 catattaaaa caacatatta atatatggta taatatatta aaacaaagta gcaaatttga
     5041 gaggagataa caatgtcaaa tataaaaata caaatagaca aaactgtaga atggcttata
     5101 aataaggtta atgaggcaaa tgcaaaagga ttaattgttg gtgtatctgg aggaattgat
     5161 tcggcagtag ttgctaattt aattaaaaag gcatttccag aaaactctat gggagttata
     5221 atgagcataa aaagtaatcc tcaagataga gaagatgcac ttaaggttat agagggatgt
     5281 gatatagaat accttgattt agaccttata gaaccacaaa gtgctatatt agacatggta
     5341 gtaggaaatt taaaagataa acatttatat agagaagaat atttaaagat gacagatgca
     5401 aacttaagag caagagtaag aatgagtaca atttatacaa ttgctaacaa tctaggatat
     5461 ctggttgttg gtacagacaa tgctgcagaa atacacacag gatattttac taaatttggt
     5521 gatggtggag ttgatatttt acctattgca aatttaacta aaggagaggt gtatgaatgg
     5581 gcaaaagagc ttggtgttca tgaagattta ataaacaaag ctccttcagc aggtctttgg
     5641 gaaggtcaaa cagatgaaga tgaaatggga actacttaca atatgataga tgctgtgtta
     5701 gaaggtagat tggatgaagt tcctaaaaga gaccaagaga taattgaaag acttcataga
     5761 ttaagtgaac acaagagaaa aacgcctgca caacctccta agttctaatt tactatttat
     5821 aagatttgtg ataaaattta caagtgatga aaattagaat aattaattgt acgtattaag
     5881 gagtggaaat atgggacgta taggtaatat aattaataga aaaggtaaac aagatgctca
     5941 aagagcaaag atatttacta aacatgctag agcaatagca gttgcagcta aggaaggtgg
     6001 agcagaccca gagtacaatg cagcgttaaa aacagctata gaaaaagcta aggcagataa
     6061 tatgccaaat gataatatag atagagctat cgctaaaggt gctggagcag gtgctggaga
     6121 agactatgaa actatagttt atgaaggata tggacctggt ggagttgctg ttatagtaga
     6181 aactttaact gacaacaaaa acagaactgc tggtaacgta agatactatt ttgacaaaaa
     6241 cggaggaaac ttaggaacta gtggatgtgt gtcttttatg tttgataaaa aaggacaaat
     6301 attagttggt ttaggagatg gagtttcaga agaagaattg atggatgttg cattagaagc
     6361 aggagctgaa gatttcataa cagaagaaga tggttatgaa ataataacta caccagaaga
     6421 tttttctagt gttcgtgatg agttaaaagc taaaggatat gagtttatat ctgctgatgt
     6481 gaagatgata cctcaaacta caactgtatt gactgaagaa tctcatttaa aaatgatgaa
     6541 taaattagtt gatatgcttg aagaagatga tgatgttcaa gatatatatc ataactggga
     6601 agtagaataa atagtataag catattgaaa tttataagta ttgaatcaat tttaacatgt
     6661 gataaatttt atagaataag aaacactaaa atagacatac gcacctctaa cctatatttg
     6721 cataataata tgtaagcata ggtaaggggt gtttttatat ttataggtta agaaatttaa
     6781 agtaaatttt gagctggact cgattgtcta taaataattg atgggtatat aacttgttgc
     6841 tgaataccat ttatacgccc agttactgta tcaataatca tcctaagact acgttctgct
     6901 gtctcttcca tttttaaatc tataactgtc aaaggaggaa tacttcttgc cattagtcgt
     6961 gaaggtccat tacttgctgc aaatatttga atatcctctc caattacaat tcccgattca
     7021 tgaaatgcat tcatcatacc aagagctacc acatcatgat tacaaaaaat tacttttttt
     7081 agtgaatttt ttgcaagcat tttttgagca atatcatatc cactatctat tttattagaa
     7141 caataatata tagaatctga tagatgtatt ccatgttctt tacatgtttt taaaaaagat
     7201 ttacccctta aagtcataca tgtaaaggaa gttgggttga atacaacagc aatatcattt
     7261 ttaccatttt gaatagcatg taaagctgct atacgaccag tttcctcatt atcaatagat
     7321 acacttgaaa aaccaggtat ttcacgattt acaacaacta caggaatttt aggtttattt
     7381 tttactagat attctatatc atcagcattg atacctgtta aaacaattcc atcataataa
     7441 ttatttgcaa aaaagtattc atcatcacat agatgaccaa ctttgtaagg tcgtatgatg
     7501 atatttatgt ttaaatgttc taaagaaatt atgtggttta ttgcttgaag tatattggtt
     7561 gatgccaact caaatccctc atcctgccaa taaaaagcta ttttaatatt attatgttta
     7621 ataggagtag agcgtttata tccaagctta tcagctgaat ttaatataag ctcttgtgta
     7681 tgtagcggaa tcctgcgttc atttccttta ccacttaaga cgtacgagac agttgctgaa
     7741 gaaagaccac agtcttttgc aatatctttg attgttgcca tgataaaatc ctccttaaat
     7801 agttgcttaa atttgcttat accaataatc ttaacatata ttcaactaaa gaacaatatt
     7861 ctacaaggtg catattttac agaattagaa taaataaatt taaaaaaact tcttacttat
     7921 gttgacataa tttagtttat aggattataa tatgcttaaa taagcttatt attaacttaa
     7981 attaagcaaa gttaagcagg aacatgcaat gctagcttgc aatgtgactg taaaggggga
     8041 aaaggtatga gtaaggtaaa tatatttgaa gttggtccta gagatggatt tcaaaacctg
     8101 aaagagtttt tagaaactga taaaaagctt aagattattg atggtcttat tgcttcaggg
     8161 attaaacaac ttgaaattag ttcatttgta agcccaaaag caatacctca gatgaaagat
     8221 gcaaaagaag tagcaactta ttgtgtagaa aaatatcctg atgtgaaact ttatgcatta
     8281 gttccaaatt tatacggtgc taaagttgca tgggagtgtg gtataagaga tatatcctat
     8341 gttatatctt tgagtgaaac tcataataaa aaaaatataa atcgtaccca tgaagagtct
     8401 attgatgagc ttaaaaaaat aatgaatact tatccagaca tgaatatatg tattggaatg
     8461 gctactgtat ttggatgtcc ttttgaaggt ttaccaaaaa ttgaagatgc cataagattt
     8521 gctaaacgcc tttgggaaaa cggtatcagg gagatgaatc tagcagatac aatagggatt
     8581 gctgacccta agcaagtaag agaaactatt agtgcattag ttgaagcttt accagagtgc
     8641 agatggcagg tacatattca tgatactaga aatatgggaa tggttaatac tcttgtggct
     8701 attgaatctg gaattactac tgttcagtct acacttggag gattaggagg atgcccattt
     8761 gctcctggag catctggcaa tactgcaact gaagatttag tatatatgct tgaacgtatg
     8821 gggtatgata caggagttga ttttgttaaa cttcttgaat tatcaaagta tcagaagagt
     8881 tttgtaaatg gagtatatag tggtcatcat gtaaatataa agtctgatag ttgtaattgt
     8941 tagttctatt gattaatcga ttaaaaaaat atgttgatta aaaaaatatg ctgattggta
     9001 aaatagattt attgataaaa aatataaatt ataaaataca ttatctaata aaacaaataa
     9061 aaaaattgag ggggattagt atggatatta tagctttact tttattttta ggagttatta
     9121 ttattgcatt tgtacgtaag aataatgcag gtattttggc tctagctatt ggtgtcatag
     9181 ctgttagaat ttttggaatg gatgataaag aactttatgg agctataagc aactcaatgt
     9241 ttactacact tgttggtata acactactct ttgcaatagt gaactcaaca ggagcattaa
     9301 agcttgttgc agaaaaaatt gtagctgctt ctggtaaacg tgtttggctt atacctatag
     9361 cagtttttat agcaggattt gttgttgctg gtgttggacc tggggcaatt ccagcacttg
     9421 caattatccc agcaatggct gttcctgtag ccataacggt tggttataat cctgtaatgc
     9481 ttgcacttat aggtgaatgt ggattaatgg caggtcgtat gactcctatt actccagaag
     9541 gtcaaattat aacaaccgtt gcagaagggg ttggaattga aaatgttatg cctactatct
     9601 tagcctgtca aactctttct acaattgtat tttcaatagt attgtttata attttcaaag
     9661 gatataaact taaaaaacct ataaatgtta tagatagtaa gcaaatagaa aaattcaata
     9721 taaagcagat aatttctcta ataagcatag tagttatgat tgcttttatc ataatttttg
     9781 atatgaatgt tgggcttgca gcttttgcag tttcagctgt acttattttt ttcaatattg
     9841 ctgatgaagg agaatgtatc aaatcaattc catggagcac gatagtaatg gttcttggag
     9901 taggtgcaat gatgacaatc gtagatgcag caggaggtat tgacttgatg agtaatgcat
     9961 tatcatcact gatgaatagt aaaacagcta ctccaattat gagtatttca gcaggactta
    10021 tgtctatggt tagttctgct ttagcagtag tttatccaac tatgatgcct atgtgtgttg
    10081 atatagctaa ggcagttgga ggagtagacc cactagcact tattgctgca gttggtgttg
    10141 gaggttctct tgctggtgta agcccacttt ctactggtgg ggcattgatt ttagcagcta
    10201 tgggttcaag taagaaagac tttaataagg aagaacaaaa taaggttttt gtacagcttt
    10261 tcattatgag tgcagttggc ttattggtta ttgcagtagt atcaatatta tcatttaatg
    10321 caataacaca tttaatgaac taattagaat aactgaaaat aaatcattaa atttaacttt
    10381 taatattaat caatataata taatttggag gggaagttat gaaaaaagga gcattaagca
    10441 atataaaggt acttgacctt acaagagttc ttgcaggtcc atattgtaca atgatgttgg
    10501 cggattttgg agctgatgtt ataaaaatag agatgccaag aaaaggtgat gatacaagag
    10561 gttttggacc ttttgtaaat ggagagagtt tatactatgc aaatataaat agaaataaaa
    10621 aaggtatcac tctaaacctt aaatcagaag aaggaaaaaa tatattttta gaaatggtaa
    10681 aacatgctga tgttgtagta gaaaattaca gaccaggtgt aatggaaaag ttaggtctgg
    10741 gttatgatga gttggctaaa gttaacaatc aaataattta tggagctgta tcaggatttg
    10801 gatgttatgg accatattca gaacgtccag gttatgatat tattgcacag gcaatgggtg
    10861 gtcttatgag tataacaggg caagaaggag gagaaccaac gagagttggt aatgctatgg
    10921 gtgatgtact aggtggaatg aatttaacta ttggtatact cacagcactc aacgctagaa
    10981 aaataatagg aaaaggacaa agagtagatg tttccctcgt tgattctgtt gtatcgtctc
    11041 tcgaaactgg tatacagaga tactttgatt caggacaacc tgaacttatg ggtaatagat
    11101 atgcttcagc ctatccttat gactctttta aggcaagtga tggaagtttt gtaataggct
    11161 gtggtaatga caaacttttt gaaaagttat gtaaaaaagt tctttttaga gaagaccttt
    11221 taatagatga gagatttaaa acaaatctta atcgttgtga acattacaag gctcttaaac
    11281 cagaaataga aaaatggtct attaagcata caataaaaga agcagttgac ttaatatcag
    11341 aggctggagt tcctgctgct cctatctata atcttgattg tgttacaaca gatgaacata
    11401 tagcaaaagc aagagaaatg attgtagata ttagtcatcc tattatagga aatatgaaag
    11461 tcaatggaaa tccagttaag ttgatgacaa caaaagctaa aattgatatg ccagcaccat
    11521 ctctagggga aagtaacgag gagatttata atggttggct tggttttgat agtgataaaa
    11581 taaaagattt aaaagaaaat ggagttattt gattaaaaaa tagctaaaca cacttgtgac
    11641 tttagtcagg ggaggttcag ttagaataat atcaaaaaat attaaatcaa tactgtaaat
    11701 caaatataga attgtcagaa gcatttaaga tgggaaaagc tacttagaca ttgagtcttt
    11761 gtggcttttc ctattttcat taagaatttt atattatcag aatagatatg tactaaacta
    11821 aagtattaac aatttaaatt aatagaaaat aaactaccta attatgttga ataaagacta
    11881 ctttagtgaa aataaactta tagagatgct atttaaatta ttttaatgga aatatcaaaa
    11941 atgagactgc attctcaaaa atgagactgc gttttttaag tattttctcg aaaatgagac
    12001 aaaaatattg ttttatgggt tttattgaag aaaaattctt ctgtgaatta caatttaatc
    12061 aattttaaag ttgaaaatta ttaaaaattt agtgaaattt atgtatattt cgtttatttt
    12121 attaaaaata acaatttttt actaaaaata aagaacttca atggtgattg gcatagtact
    12181 tgctatttta tattaacaag aaatgtagaa aaaataacaa tgtataatgg ggggaatatg
    12241 atggaatctg taatggaaaa tttgaacaat cttaaggtgg aggttaagga caaagtctgt
    12301 gttattacta taaatagacc taaagcttta aatgctctta atagtgacac tcttagggaa
    12361 ctatcacaag ttattgatgt agtatcagaa aatgaggcaa tattaggagt tattattact
    12421 ggagaaggta aagtttttgt agccggtgct gatatacgcc agatgcaaaa ctataaaagt
    12481 gaggaaggca gaaaatatgc aggttatgct cagggagttt ttgataaaat tgaagctctt
    12541 gaaaaaacag taatagcagc agttaatgga tatgcattag gtggtggatg tgaacttgct
    12601 atgagttgtg atattagaat tgcatcagaa aaggctatat ttggacaacc tgaagttaat
    12661 ttaggagtta ttccatgttt tggtggaact caaagattat caagacttgt tggaactgga
    12721 atagctaaag agttaatttt tacagggaga caagtaaatg cagaagaagc taaatctatt
    12781 gggcttatta ataaagtggt tccaagtgat ttacttttag aagagtctat gaagatgatg
    12841 aaccaaatag ttgaaaaagc gccaatagca ataagatatg caaaagttgt tattaacaaa
    12901 gggatagata tggatttaaa gaatgctctt gaactagaga aagatattgc aggtttaact
    12961 tttgctacaa gagataagca agaaggaatg aatgcattta tagaaaagag aaagccagtt
    13021 tttgaaaata agtagctatt ataactaaaa ttggaacaat gtagaatata ttcaaaatct
    13081 aaatttcgtg aaaaaataca tatagtttaa ttttaaaagg agttaattta tgaatacggg
    13141 agtaattata agtttagtag ggattatcat agctctatct cttctagttg taatggttat
    13201 gaagggaata aatattttta ttatagcaat tgtatgttca tcattagttg ctataacagg
    13261 aagcctaaat gtgtatgatg cacttaaagt ggattatatg acagggtttg ttggatttct
    13321 tcaggcaaat ttctttattt tcctaacagg gacattaatg ggaaaaataa tggagattac
    13381 tggtggagca aaatctattg ctaagatgat tgtaagatgg attgggaagg ataaagcact
    13441 actttctatt ccaatagctt gtggaatatt agcctatggt ggagtaagtg ttttcgttgt
    13501 aagttttgca gtgtttccga tagctttaga aatttttaaa gaagctgatt tgccacgaag
    13561 atttatacca gcagctttga cttttggatg ctcaactttt gctatggttg caccaggggc
    13621 accacaaatt cagaatattg ttccagcatc aacattaggg acagatatta tggctggagc
    13681 agtaaatggt tttatatcat gtgcagtaat gtttatagtt ggaagtacaa ttttgtacaa
    13741 aatggtttca aaagaaaaag ccaatggtgg tcattttata gcacatgaat cagatatatt
    13801 tgatgaagca gaagcaacta attctaagag agaaaatggt cccaatggtg taattgcctt
    13861 aattccattg atagtgtcaa ttttaataat taatgtaaaa gttaatggaa aagcgatagt
    13921 accaattgag gtgggagtat ttattggagc tttattagta tatttattgt taaataaata
    13981 tcaagataat actaaaatag ttggacatgt tggtgatgca tgtaaaacta cagtagtagc
    14041 aatatgtaat acttgtgctg tagttgcatt tggttcagta gtaaaatcag cagttggttt
    14101 tgacttcata gttaatgcta tgactaatat tcctggtcct cctattgcag gggctgcagt
    14161 tggaactaca gttattgcag gtatttgtgg gtcagcttca ggtggactag gaattgcagc
    14221 tccacttctt ggaccagtat ttttagccaa gggtgtttcc gctgcagcat taactaggac
    14281 tatggcaatt tcatcagcag cattagattc acttccacac aatggatata ttgttactgt
    14341 aacaaatggt ctttgtaaag aaacacataa ggatgcctat atgccaatat tctgggtaac
    14401 tgttttaacc ccatttattg gaaccatagt agcagtccta ctgtttacaa tgttcccggg
    14461 attgccataa gagaaaagat aaaaggtata aattatattt tgatgttata aaatcaattt
    14521 tcaaaatata tacaataaat ttcatgtttt aatactgtaa atatgtattt aaaataacaa
    14581 attgaccata taaggaggaa ttgaaagtgt taaataaacc attagaggga gttaaggtta
    14641 ttgacctaac gtattttgta gcaggtccag ggacttctaa aatattagct gactggggtg
    14701 ctgacgttat taaggtagag ccaagctttg gagacccagg aagaaagaca ggggcaacaa
    14761 tgacaatgcc aatagatgat tataataatc ctttttacag cacatataat tcaaataaaa
    14821 gaggtttgtc tataaatctt aagagtgaaa ctggaattga aattatggat aagcttttaa
    14881 gcgaagcaaa cgtatttgtt tcaagttata gaacaggagc attaaaaaga ctaggtcttg
    14941 attatgaatc attaagtaaa aagcatccac accttatctg gggtcagata aatggttttg
    15001 gcgattttgg acctgctaag gataatgcag gatttgatac agttgccttt tgggcaagaa
    15061 gtggggctat gcttgatata gcagaaaaag atacaagtcc aataaatcca cctatagcct
    15121 ttggagatgc aacaacttct tgtagtttat ctggaggaat atgtgcagct ttgtaccagc
    15181 aagctaagac tggaaaagga caaaaagtaa tggcatcttt atttgggcaa gcaatatgga
    15241 atgcatcatc tttattagca tctacacagt ttagtgatga gtatccaaaa actagaaaaa
    15301 atgctatttc accagtaata aattcttatc gttgtaagga tggaaagtgg atattcttaa
    15361 gtattttaga gcatgaaaga tattttgagg cactttgtag attatttgga agagaagact
    15421 taataaaaga agagaaattt gcatcttcag tagaaagtaa gaaaaatgct acagaactta
    15481 ttaatatttt agatggtgaa tttgcaaagt ttactcaaaa tgagatggtt gaaaaactta
    15541 ctgctgctga tatagctcat gaaaaaattc aacatgttaa tgatgtagtg actgatgaac
    15601 aggctattgc taataactat atatatgaac atacaagtaa agatggaaat aagacaatgc
    15661 ttgcatctac tccagttaaa tttggaaata ttgaagttaa catgacttgt gatgctccac
    15721 ttataggaga acattcagat gagatattga gagaacttgg atacagtgat tctgatatag
    15781 aggctctaat tgaatctgga attgtaacaa tgaataaaga agcatgtgaa atatgttaat
    15841 aaacatgtga agtatgttaa taaataggag ggaattttat ggattttaga ttaacagaag
    15901 cacaattaat gcttcaaaga gtagcaaaag aatttgcaga gaatgaaata gcaccaatag
    15961 ctgctgaaac agataaaaca ggtatttttc caagggagct ttttagcaaa atggctaaaa
    16021 taggatttaa tggaattgga acacctgtag agtatagtgg ttctggtggg gcagatatag
    16081 aaaaggtaat tgttgttact gagattgcca aaaaatgtgc agcatctgca gcaatattat
    16141 caatacacac aatatatgct caagctattt tgaaatttgg tactgaggaa caaaagaaaa
    16201 aataccttcc aatgatggct gaaggtgggt gtgtaggtgc ttttgcctta accgaaccta
    16261 atgctggttc agatgctgcg agagctgcaa caactgcaat tattgatgaa gaaactgatg
    16321 aatatgtttt aaatggaact aagtgtttta tttctggtgg aggtcaagca gaatcattaa
    16381 taatatttgc attgacagac ccatcaaagg gaataaaggg aatgtctgct atcattgtcg
    16441 acaaaggtac gccaggtttt tcaataggaa aaattgaaga aaaaatgggt attcatggtt
    16501 cagaaactgc agagttaata tttgataact gtagagttcc aaagtctaac ttattaggaa
    16561 aagaaggtaa aggatttaat atagctatga cttgtttaga tggagcaaga attggagttg
    16621 gagctcaagc tgtaggaatt gctgaagggg ctttagaaga aagtatcaaa tattctaaag
    16681 aaagagtcca gtttggcaag ccaatttcag ctttgcaagg tattcaatgg tatatagcag
    16741 atatggcgac aatggtggaa tcagcaaaat tattagtata ttatgctgca gatttgaaag
    16801 ctagaggaga aaaacacact aaagaagctg ctatggcaaa atacaatgcg tcacgtactg
    16861 caagagaggt tacaaattta gcccttcaaa tccatggtgg atatggatat atgaaggatt
    16921 atccattaga gagaatgtac agagatgcca aaataacaga aatttacgaa ggtacttcag
    16981 aaatacacaa agttgttatt tcaagagcag tactaggata ggaggaaaag aatgaatata
    17041 gttgtttgct taaagcaagt tccagatact aatgaagtta aaataaataa agagacaggt
    17101 actctaataa gagatggtgt accaagtata atcaatccag atgatagaaa tgctttagaa
    17161 gaagctctaa aaatgaaaga tgaactagga gcagtgatta aggttataag catgggacct
    17221 cctcaagcta aaagtgcttt aaaagaagct ttggcaatgg gagctgatga agcttattta
    17281 atctcagata gagcttttgg tggttcagat acttgggcta catctacaat tattgctgct
    17341 gctatagaga aggttggaaa gtatgatgta atattctgcg gaagacaagc tatagatgga
    17401 gatacagctc aggttggacc agaggttgca gaatttttag ggataccaca agttacttat
    17461 gcgaaagaag taaaggttca agatgacaaa ttactagtaa ctcgttatac agagacaggg
    17521 gattatttaa tagaagcaaa gatgccagtt ttattaactg ctataaaaga gttaaacaat
    17581 ccaagatatc caagtgtcaa gggaatctta gaagcttata ataatggaga tgcaaagatt
    17641 actgtattaa cacttgcaga tttagatgtt gatacaactc aaattggatt aaagggttca
    17701 cctacaaacg tttataagtc ttttgtacca gttaaagaca agcataatga aataatagaa
    17761 ggtataaata aaaaagaaaa agctgagaaa ctaatagaaa tactattcga tttgaaacta
    17821 gtataggagt gttaagatga tgagagcaaa agttaatcaa ggtataaatt taaatgatta
    17881 taatggtgtt tgggtaatag gagagcaaag ggaaggtaaa attaatcctg ttacgataga
    17941 acttattggt gaaggaagaa agcttgctga ccaattagga aaagagcttg cagttgtgat
    18001 agctggatat gaagtagaga aagaagtgaa ggaattactt cactatagtg ttgataaagt
    18061 atattacatc aatgaccctc ttcttaaaga tttcactact gatggatatg caatttcaat
    18121 tgcaaattta atcgaaagaa aaaagccaga ggttgtattg gttggtgcta cttctatagg
    18181 aagagatata gcgcctagaa ttgcaggtaa ggttggaaca ggtctaactg ctgactgtac
    18241 aaaacttgaa atagattcaa cagataataa gttattacaa acaagaccag catttggtgg
    18301 aaatttaatg gccactattg tttgtccaaa aaatagacca cagatgtcaa cagttcgtcc
    18361 aggagttatg gcaaaagctg taagaaacga atcagagact ggaattttag aagttgttac
    18421 tccagaactt actgaaaaaa tgattagaac tagattagta gagatacttc cacaagaaaa
    18481 gaaatctgta aatctaactg atgctagaat aatagtatca ggaggaagag gattaaaaag
    18541 agcagaagga tttgagctta taaaagaatt ggctgataaa ttgggggcag agattggtgc
    18601 ttcaagagca gcagtagatt cagggtggat agaacattct catcaagtgg gacaaacagg
    18661 aactactgtt agaccagaac tatacattgc atgtggaata tctggagcaa tacaacattt
    18721 agcaggtatg agtgattcta aatatatagt tgctataaat aaagatgcaa aagcccctat
    18781 ttttagtata tgtgactatg gaatagtagg agatttatat gaaattatac ctgaaatgat
    18841 agaatcatta aataggtaac ttttagaaaa cattgaatat gtagaatgat aagtcttata
    18901 atattgtatt gtaagactta ttatttttgc tgaaggttat agtggggaga tgaaacaatg
    18961 aaagagcagt ggtataagga tatatttgca agagtattat ctatgactga tgatggtttt
    19021 attgttgtaa atagaagtgg agtaataata gatattaatg ataaatattg tgacttttta
    19081 ggaaaagaaa gaaaagatat aataggacaa aatatacaaa gtattatacc aaatacaaaa
    19141 atgctagatg ttatgaaaaa taagtattgt gaagaaggag ctatacatca ttattcaggt
    19201 ggaaatacaa aagaaaaaag tgtaatagta agtaggtctt atgtggaaaa tgacaatgga
    19261 gaagtagttg caggagtagc tcaagttaaa tttagattgc aatcatttga tgtagctaaa
    19321 aagttaatgt cagaatatat ggagctccaa tattataaag agcagtttaa ggataactgt
    19381 ggttttgaca agctcatagg tgaaaataga gacttcatag aacttaagaa aacaggtgtg
    19441 aaagcttcta aaacaaactt tccagtactt ttaacgggtg aaacaggtac aggaaaagaa
    19501 gtctttgcta gagcaattca caataatagc agtaggtcag ataaacctat ggttagtata
    19561 aactgcgctg caataccaga agaattatta gagtcagagc tatttggcta tgacgaagga
    19621 gcttttacag gagcaaaaaa gggtggtaaa aaaggtaaat ttttagttgc gaataatggt
    19681 acaatctttt tagacgagat aggtgacatg cctttgacca tgcaagcaaa acttttaaga
    19741 gttcttcagg aaagtgagat agaaccagtg ggaggtctta aaactataaa gatagatgta
    19801 agagtaatct ctgccacaag aaagaattta agtaaaatgg ttgaagaggg attatttaga
    19861 gaagacctat actatagatt aaatgtaata aacattcata tgatggaatt gaaggacagg
    19921 caagatgata ttttattgct agcaaattat atattaaaca aattaaatgt tgaatacaag
    19981 gaattgaagg ttttaagtga taaggttaaa aattgtttta ttaactatac ttggccggga
    20041 aatataagag aactacaaaa tgtaataaaa agtgcctatg ctgtaagtga tgatatggtc
    20101 attatgatgt gtgaccttcc atctaagatg gataatatca gcagagtagc tcaatgtaat
    20161 gtggatagca attgttcaat tcatgaaatg gttgagaatt atgaaaagag cttaattatt
    20221 gatgtgttaa ggaagtataa ttggaaatgt tctaaggcag cagaggttat gggaatacac
    20281 aagagtcttt tatataagaa aataaaaaag tatgaaattg aattaaataa ttaagataaa
    20341 ttgaattaag gcaatgctaa aaaaacgccc ttattcaaag cgaactgtat aaactgtttt
    20401 atgcagttaa aacgtgtaaa agtagatgtg aagtactaat gtcaatcatt agtacttttt
    20461 tattatattt ataattacta tctatatttc agtatctttt gatatctaag attattatgt
    20521 ttaatttagg atataacaaa accctcttag ttatggacag ttttttatat tttaactgtc
    20581 tactaagagg ggatagttta gtttaaattt agagtaaatt ttatctagca tttataaaaa
    20641 atattttgaa tagctttttt gttatttaat cataattttc tacttcttta tcaagttctt
    20701 tgccacaaga atcacactta tatatagcat tgtatccgta atcatattca tcaactattt
    20761 tcttttgtct aaatacacca ccacactcac ataggaaacc aatttttata agtgtaacga
    20821 taaattgtga ttttataaat tttatatcat tacatttatc gttagtgtaa aatgtataaa
    20881 tataagagtt atcgcactca tctcttaatt caaatctttc aatatatgtg ttatttttta
    20941 attcctcaaa ttcttcttta gttaaatatg atttttgttg caattcatgt aaacgcttaa
    21001 tttggtccat tatttatatc ctcccaataa ttttagtatt ttaagcttag ataaggaatc
    21061 taagttttat taaatttatc ccaaggaatt atttaaatca tatttagttt tattaattac
    21121 aacatatata aattacacga aaataaaact aattgtaaaa ataatatcct gtgaaaacct
    21181 aaactactaa ccccttacta acccgaaaac taaaaaaaga aaatatatcc aaatataagt
    21241 gatatataaa taaagatgtt tcatataaat ttaactttaa atattctgac aataatatat
    21301 ataaatatat tatagttaaa atataccaca tattttgggt attgtatact ggaattagag
    21361 taattaattt attttttaac atacaaatga ttttatgaaa aaaaacaaga ctcaaaaatt
    21421 tttatattct ttgatagaat aaaattgaga gtaaatttat tgaattttat aaaatttata
    21481 aggggtgagt ctaagatatg catgaagata aaaatgatat atttgaatca atagatactg
    21541 aggattttga taataaaaca gaagaagaat gtttagagct agtaagaaaa aatggattga
    21601 atttaatata cataaaaaat caaacagaag agatatgtct agaggctgtt agacaaaatt
    21661 gtaatgcaat aaaatgtgtt cagaatcaga cagaaaaaat atgtatagaa gcagttaaac
    21721 aagattggag aatgttagaa tttgtagaag agccaacaga agaaatttgc atgttggcta
    21781 ttaaccaaga tggaacagca ttaaaatata tagaaaatca gacagaggag ttatgcttaa
    21841 gagccgttga aaaaaatggt gcagctttgg agtatgtaaa agaacaaaca gaagaaatat
    21901 gtatagaagc agttagaaac agcgaatttg gattggcaag agtgaaaaat caaacagaaa
    21961 aaatatgtat ggaagcagtt aagcattgta gctataatct aaaatgggta gaaaatcaaa
    22021 cagaagaaat atgtatggaa gcagtgagac aaaatgggct tgatttgaaa tttgtaaaaa
    22081 atcaaacaga aacaatctgt ttaagagcag taagacaaaa tggaatggca ttagaatttg
    22141 taaaggaaca gactgttggt atatgcttaa aggcagtaag acaatatgga atggcattaa
    22201 aatttgtaaa agaacaaaca gaagaaattt gtacagaagc tataaaacaa gataaaagag
    22261 cacttagttt tgtaaaagga gataaggaaa aatacaaggc tctatatgat aataatgaac
    22321 catttgcaaa gagatatgtt agaaatgtaa tagaaaaaga aaacagagca ttgattaaaa
    22381 aaggagaaga aaatgcaaaa atcaaaattg caggaaaact ttatgataga ggcatgtctt
    22441 ttgaagatat atcagatata gttgagattg aaataagcaa gttaaaagtg agtttaggtg
    22501 ttttttaagg gaaatagtta ataaaaaaat aatcgactag ctctttgtag gacagcaaaa
    22561 ttagtgatat aatttgatgt ataataaatt atttttatta gataaggggg aattaaagtt
    22621 gaagattaca gtattatacc aaacaagaag tggaaacaca gaaagggtcg ctaagctgat
    22681 agaagagggc gctaaaaagg tggatggagt agatgtaaag cttatgagac ttgataatat
    22741 tgatttagat tatttaaatg aaagtaaagc agtaatattt ggaacaccta cttatttagc
    22801 aaatacaact tgggaagtaa aaaaatggtt tgatgaagat tcaaaaaaag ttaatttagc
    22861 tggaaaatta ggagctgttt ttgctacatg tgattatata tgtggaggtc cagatgttgc
    22921 gatacttact atagtaggac atttgatggt taaagggatg cttgtgtatt ctggaggtgg
    22981 ttctttagga aagccattta tacatttagg acatgtacat tcaattgaag gtccagagtt
    23041 acaagatgag aaggctataa tatttggtga aagaattgct actaaggcaa aagaactatt
    23101 tgcttaattt ctatatgcat aataatgatt agagtaaatt tagggtttta atggagattt
    23161 gaagtaaaag ttataaaata aaaaattttc cataaaatta ctcaagatga attataatat
    23221 aattataaat aaattatatt attaaaatat ttaaaatcaa acgtcaatag cgagggaagt
    23281 ttatggtatg gcatatagaa tatgagattt tttctgcaat tatagttatt tttttaatgg
    23341 tatacttttt tagaagtaaa tttataccta ctttacaaaa caaaatatat tgtgcacttt
    23401 taatattctc atttttattt ataatttcaa atattttagg ttcattttgt ctaaataata
    23461 tagacaaaat tccaattttt attacttttt tattgaatca gatatactta ttgttattgc
    23521 caataccagc agcacttgta tcattttatg ttatggctat tatttatcaa gatataaggt
    23581 atatgaaaaa aagattatta tttttatcta taccacttat aatttgtata atcttatcta
    23641 ttacaaatcc ttttacgcat attctatttg gattgtcaaa agaaacaggt tatatacgag
    23701 gttgtggata tgttgcaact tttgcatctt ttttctttta tgcaatatat tcagcatttt
    23761 tatcttttaa atatagaaaa gcaatgcatg aatcaaaaat atgggctatt agaggttttc
    23821 ttatagtttc aattgtggca attatcttac aggcaatttt tttacagtat cttcttacag
    23881 gaactgcatg tgcatgtagt ttacttttga catatctttc tatgcagaat cgaggtctta
    23941 ttattgatga ccttactggt gtactcaata gacaatcttt tattcaagag ctagatttga
    24001 atatcaatac tgaacaatca ggatttatta ttacaattgc gcttgatgat tttaagttta
    24061 tgaatgaaac ttttggaaca aaaaatggag atattgcact aaaagaagtt ggaaaatatt
    24121 tgattcagat acatgatgta aaccatgtat atagaatagg gggagatata ttttctattg
    24181 ttgtcaatag tcaattaggt atagaaccag atgatattat cagaaagata gaagaaagat
    24241 ttaaaaagcc ttggctagta gaagagataa gttttaattt agcaactagt attgctgttg
    24301 tttattaccc agaaaatgca gaaacgacag aagatgtaat tgttgctata gatttctcta
    24361 tacatgaagc aaaacgttct gagtcaaggc gagttgttta tgcagatgcg tctataagtg
    24421 aaaagataaa gaagaaacat gttattaaaa attgtttaaa agaagcatta aaaaatgatg
    24481 ggtttgaagt gtactaccaa cctatatttt ctaatagcag gggcaggttt acttcagcag
    24541 aggcattact taggctagaa cacaaagagt taggttttat acctcctgat gaatttattc
    24601 caattgcaga acaaacagga ttgattaact caattggatt agtagtcttt gagaaggtat
    24661 gtagatttat agctagtgat gagtttgaag atttaaaatt ggataatata gctgtgaatc
    24721 tttctgtagt acaatgtatg caaaaaaact tagctgatga tttactttat cttatgaata
    24781 aatataatgt atcaccaact aaatttaaac ttgaaattac tgagactgtg gctatgggct
    24841 cttttaatat aattaaagaa acaatggaaa gattaattga tttaggtgtt aagtttgcac
    24901 ttgatgattt tggaattgct tattctggag ttactaatat gctttcttta ccattttcag
    24961 taattaagtt agataagagt ttgatttggt ctatgaatga agatagtagg cataaactta
    25021 cagttgagac gattatagct cttataaata aattgaatat gaaggctgta gcagaaggtg
    25081 ttgaaaccat taagtgtgct gaagatttaa tagctatgga gtgtgaatat ttgcaagggt
    25141 attatttttc taaaccagtt ccagaagatg tttttaaaaa tttgttgaaa gaaaatactt
    25201 ttacaagtta acacccttta tttttttaat tacaactttg ttcattgaca ctgccagcga
    25261 tatattataa aattaacaca ataataaata ttaaatttat tatacatatt attaatatta
    25321 attaatggag taaagattta ttatatattt tatttaatta tcctaaagtg agaaaggaag
    25381 atgtgacatg aataaaaaga aaatattagt gccaattgat gggacagaaa gaagtatgca
    25441 ttctttggaa tttataaaag gaatatttaa aaaagatgaa gttgaagtag aaataatgaa
    25501 tgtaaaagaa ctagtattta ttgatggcat atccctggct gaagagataa aaaattctga
    25561 aaatttagga agaagaatct tggataaagc agcagagata atgggagagt atgatgttaa
    25621 agtacatttt acttttggat atccaggaga tgagataatt agaaaagcaa aagaagataa
    25681 tgtagatttt atagttatga caaaatctac taaaaaaggt cttacaagaa tgataggttc
    25741 agtaacagca agtgtagtta aacaagcaaa atgtatagtg atgattgtac cggagtagaa
    25801 ttagaaaggt atttgaaata tgaataaaaa gatagtagca gtttgtgaaa gtgaaagaag
    25861 tttaaattct cttaagacag ctgcaaatga tttaggattt gatttagttt atgaaattca
    25921 agaaaatgat aatataaaaa atgaactttc tatttatgat atagaagatg catccatagt
    25981 gttatttgtt acaagtgatt ctatagaaag catagagaag attgatagat ttatagatag
    26041 agaattttat gaagttgatc caaagtatat aatagaggat gcaaaatcta tagtaagtga
    26101 aattttaata gacttaaatt aatcgtgggt gtcgcactaa gaatagagcg acgccttttt
    26161 atatatttta cacaagaaat aaagaggttg tatcaaaata tagataagag tctttttcat
    26221 tgttgaaatg atgaaaatat atttgatttc atacaaaaaa gagtacctca taactaaaaa
    26281 gttcactttg agacactcca tttttatatg ttagttgcat ttaaggtaaa atagaagttt
    26341 aatcatgttg aaataactga attacatctt ctaaatgatt gtacattgat gtataaccta
    26401 agtaagagtc tttactatca aatgcaatca ttatcttgtt atggtggcta atcatatcct
    26461 tgagagaatt tctatattta aaaccaaagt attggttaga agaaactgtt ttaggtatta
    26521 actcataata ttttataaaa attggattat gagaagctaa aattatctct ttgtgaaatt
    26581 gcaagtcagc atcataacat tcttctatca aaccgtgaga aaccttatcc aattcttcta
    26641 ttgactttag gtaagtatat tttatttttt gaagttcttt agatgtagca tttaaaattg
    26701 ctagtttagt agcttcactt tcgataagtt gtcttgctct taaagattct acataaaatt
    26761 cttgtatgtt atgattttta tagatttcac catcatcaaa taggtcaact tttttaaatc
    26821 cttcaactat aggacttgaa taaggcacag ctctaagtat tccttcctta cagagtatat
    26881 ttatggcatt tcttacaggt attctactta tgttaaatag gtcagcaatc tttctctcac
    26941 ttggtaattt actattaatt ttaaaagttc catttagaat gtttaattta atataatcaa
    27001 taattttttc agtggcattt aagcttttca taaaaactcc taaacatata atttttttat
    27061 gattgtatta tatcatagtt aagagttaaa tctacttttt tataatatgt ataagacagg
    27121 atagaggcca aaatagctat aatagccaag ataaagtatc catattgtat tgaagtatat
    27181 tccgatattt taccaactat cattggaaat acagacattc ctatagcata aattgcttga
    27241 aaaaaaccca ttgcagtaga tttctgatgt tttggtacat ttttcataga ctcgctagta
    27301 aggtaagaaa ggagtatacc tgtagatata cctggtagta cttgtagtac aaatattata
    27361 ttaatatttt ttattgttgg aactaaaaag caataggctg aaactaaaat aaaaactaaa
    27421 ggaatccaaa attttggccc atacttagta caaaatttag tagaagcaaa gccagaagaa
    27481 gcaacagcac acaccatgta aaatatagaa gatagaccta tgagggtaga actagaacct
    27541 aagtttttaa gaatttgagt agtaaatgac attgttgtag acatttgaat accctgttga
    27601 attaatgcca taaaggaaaa aaatacaagt cttttatcct tgcagataga taaatatttt
    27661 ttaattgata ttttttcagg tatttttttt gaattatgat tttttatatt taaggctaga
    27721 atcgttccaa taactgaaga caatacactc atgatacata aggctgtcat tcctaatttt
    27781 tcataaaata aagtactcat aacaaatcca atcaacattc ctagattgtt tactaatatt
    27841 attgtacttg tagctttttg ttgatgttct gtagaaaaaa agttggtata gtgaaccatg
    27901 taagaaatcc aagttgatga tgatattcca gataaaatgt tagctataag aaaaccattg
    27961 cctccaggag aaaagactct tataagagat gctaaaccag caaagaaaat tccagacagt
    28021 ataaatattt tatgtttatt tatggaatca gcaaatactc caacaggaag ccttaataaa
    28081 cattgtgaga ttccatatgc acctattatt ataccaatca tatttgtaga tacattacat
    28141 gcacttaaat atggattttg gaaaggtata tatacatatt gtgaaaacca gaaaaatgta
    28201 acaatagaaa gtaaaagtaa tttttgatta gatatttttt tcatattatc ctccgtatgg
    28261 tatttttata atgcaaataa tataccattt ggatttttta atcaagtact ttctctatta
    28321 aaaaaaattt aaatatataa ttattattta caaaaaaatt atactttata gttgaattaa
    28381 gaaaacgctt atgatactat aaagttaaca aatttgaata tataacagta gacgtgttac
    28441 tggtaatgca ggcaagatcg aatcaatttt tatagattat ctatagagta ctatgggtat
    28501 aatctattta tttggttcga tttttttgtt taattggcca taaaacaaaa agcctatagt
    28561 tgaaaatgga ggatttttta tggattataa aaatatagct caagaaattc tactaaatgt
    28621 aggaggaaaa gagaatgtaa atgaagtgac tcattgtatg acaagactta gatttaaagt
    28681 caaaagcgct tctaaagtga ataaggataa attatctaaa actgaaggag taataactgt
    28741 tgttgagagt atgggtcaaa tacaagttgt aattggaaat aaagtaaaaa aagtatatga
    28801 tgaggttata aaaattgtac ctcaatcaaa taacgtaggt aaaaagaatg aaagtcaaga
    28861 aaagcaaggt ataattaatt ctatattatc agcagtagct ggtatattta cacctacaat
    28921 acctgctata gcaggggttg gtatgattaa aggtatttta tcagttcttg ctatgtatta
    28981 tatgaataaa aatggagtag atataaaaga aacgcaaagc tatattatct taaatgccct
    29041 ggctgattct atattctatt ttatgcctat tatactagga tatactgcgg ctaaagtatt
    29101 taatgcaaat aaaataatat ctatggtatt aggagctaca ctttgttatc caacttttac
    29161 tgctttgatg gcaggtgaag aatctgttag atttttagga ttggcagtaa caaaagctac
    29221 gtatacatca tctgttattc caataattat tgctatatgg gctctttcat acgttgaaaa
    29281 agtattagaa aagtatatac ctgaggtaat taaaataata atggttccaa ctttatcatt
    29341 ggtagtaatg ttacctgcaa cattattttt atttggacca atcggaattt atataggaaa
    29401 tgtcataaac ttttcttata agtatattta tgaattaagc ccagcattgt gtggagcatt
    29461 tgtaggtggg ttatggtgtg tgttggttat atttggtgct catagagcat tattaccaat
    29521 aggtataagt gatgttgctc aaacaggaag acagaattta ttggcatttg caggagctgc
    29581 aaacttttca caagcagggg ctgctctagg agtattcttt aaaactaaaa atcaaggact
    29641 aaaaacaatt tctatgtctg caactataac agctttattt ggtataactg aacctgcaat
    29701 atacggtgcc aatcttagat taaaaaagcc tatggtatgt gccgtaatat gtggtgcatt
    29761 tggaggtgcg ataatgggaa tgggtggagc ttatggtaat gcatttgcaa accaaggtgt
    29821 tttaactata cctgtatatg ctgaagcagg tgcattaggt ttcttaagtt atctaggtgg
    29881 ttgtgctata gcattttttg gttcagctat ttcaacttat ctagttggat ttgaagattt
    29941 ggaagagtct tctaataagg aaaattcatc tataaaagta gaaacgaagg atggtgttat
    30001 tgatataact tcacctgtag agggcgaatg tatagaattg tcagaagtaa aggatgatgt
    30061 atttgcttca aaagctatgg gagaaggtat agctgtgtta cctacaaaag gagtaataac
    30121 agcccctact gattgtgaag tagcttcttt atttccaaca ttacatgcaa taggattaaa
    30181 attagataat ggagcagaaa tgttaataca tgttggaatc aatacagtag agttaaatgg
    30241 taaatacttt accaaacatg ttaatcaagg agatttagtg aaaaaaggtg ataaacttat
    30301 atcgtttgat atagataaaa taaaaaaggt tggttatgat gtaactacgc cagttatagt
    30361 aaacaataca tttgattttg ggcaagtagt ttcttgtaaa tctagttatg tttcaaccaa
    30421 tgataatata atttcattag tattagctgg taattaagtt aatttgacta gagataagta
    30481 aattgattta aaaggaaata agtaaatcaa caattaaata catctaaaag taagtttatt
    30541 gcaatgaatt gttaaagaaa ataattaata tggagtaaat ctattgcaat gaagtaacaa
    30601 agaaaataat taatatagag taagtttatt gtaatgaatt gttaaagaaa ataattaata
    30661 tagggtaaat ctatttcaat gaaataacaa agaaaagagt taatatagag tgaacttatt
    30721 gcaatgaatc aacaaagaaa ataattaata aaaaggagaa atatttatga atacaggatt
    30781 tccaaaagac tttttatggg gagcatcatc ttctgcattt caagtggaag gagcttggga
    30841 taaagacaat aaaggaaaaa ccgtagccga ctataattct tttaaaaagt ctcatttaca
    30901 ggcagatact aaagtcgcat cagactttta ccataattat gaagaagata ttgaattaat
    30961 gaaagaatta gggatgaaaa catatcgttt ttcaatttca tgggcaagga taataccaga
    31021 tggtgaagga gagataaacc agaaaggttt agacttttat aataagataa tagacaaact
    31081 aatagagtgt gatattgagc cattcgtgac tttataccat tttgaccttc catttaaatt
    31141 agtagagaaa tataatggtt gggaaagtag agaaactgtc tatgcttttg aaagatttgc
    31201 taaaatatgc tttaagcatt ttggagatag ggtaaagtat tggcaacctc ataatgaaca
    31261 gaatttaatt gttagagtgg aggagagaat taatatatat gatgaaacag attcatggaa
    31321 gatagataaa atgcgtgctc agatggatta taatctttgc ttagcacatg cattagcagt
    31381 caatgcatgt catgagatga taaaagaaag taaaattgga gcagcagtat catcatctgt
    31441 aacatatcct cttacttcta agccagaaga tatatatgca gctagaatga atgataattt
    31501 taaagtgtac tatatgcttg atatgcatca ttatggagaa tatccagggt attatatgaa
    31561 gtatcttgaa aaaagaaata tagttcctca catggaagat ggggataaag agatacttaa
    31621 aaaagctaaa atggatttta tagctgtaaa ttattatagg acaaattgtg cagaagcttt
    31681 acctgaagat tcacaacatc catttggatt aagagaagga actgttgatt ttagtatgta
    31741 tggactattt aaaatgtcaa tgaatcctaa cttagaggct tctgagtatg gagcagcaat
    31801 agacccatca ggtcttagag ttgccttaaa tgaatattgg caaagatatc ac
//
LOCUS       DAJMZY010000038        31514 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.038, whole genome shotgun sequence.
ACCESSION   DAJMZY010000038 DAJMZY010000000
VERSION     DAJMZY010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 31514)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31514)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31514
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.038"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            26..361
                     /locus_tag="OE968_001733"
     CDS             26..361
                     /locus_tag="OE968_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCP7219014.1"
                     /translation="MYNIDDMIYNCPVEALSNILGKKWVAIIIWKIQEDKKRFGELQR
                     AIPDCSKKMLVQQLDFLIEQGIIVNQKKLVNNVVESTYFLSESGLRLLPVMEKMIMWS
                     NKNLNCDKY"
     gene            498..1775
                     /locus_tag="OE968_001734"
     CDS             498..1775
                     /locus_tag="OE968_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HCP7219015.1"
                     /translation="MQNVNLFLVFIEGIVSFFSPCILPILPIYLSILSNSSVENLKEG
                     KTSFIGSSLFKNTIFFALGISTTFFILGSSVKVLSMFFNENKDLIMFIGGIIIIIMGL
                     FYMGIIKSSILNREKRFNVKFKEMKAITAFILGFTFSFGWTPCIGPILASVLVMVSSS
                     SNHLSANLLIAVYTIGFILPFIITAMFYSKLFKTIDKIKSNMEIIKKIGGIILIVSGI
                     LMMVNGFGSISKHFNTSQNSKIESKQEENKRENSTDKEENSDGNDSQKDSNNDNNDKG
                     SNDEDRIKSIDFTLTDQYGKTHKLSDYEGKVVFLNFWATWCPPCKEEMPYIEQLYKDY
                     NKNNDDVVILGVASPNLGREGSREHVVNFLKEQGYTFPVVLDEDGALAYQYGINAFPT
                     TFIIDKEGYVTQYIPGAMDKATMASFIENQRNK"
     gene            1896..3284
                     /locus_tag="OE968_001735"
     CDS             1896..3284
                     /locus_tag="OE968_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HCP7219016.1"
                     /translation="MKKTFDAIIIGFGKGGKTLAGDLANRGLKVALIEKSNKMYGGTC
                     VNVACIPTKSLENSANSVKTKNINSWDEVQAEYEKAIDKKETLITKLREANYNKLNSN
                     ENVTIFTGMGTFIDEKTVQVKTENEIYELVADNIFINTGSRPFIPNIKGIENKNIVYD
                     SESLMNLRVLPKKMTIIGAGFIGLEFAGIYSSFGAEVTILNSNNGILPNEDVEDSEEI
                     IKLLAKRNVKIVNNANIKEIKEVSELAIVEYEVDGKSKELTSNMILVATGRKANTEGL
                     GLENAGIELNERGFIKVSETLKTNKEHIWAIGDINGGPQFTYISLDDYRIVINQLFGD
                     KTRTTNDRKNIPNSIFISPAFSRVGLNVKQAKEKGYEVLVAKMPVEAIPRAKQIGKAD
                     GFIKIVIDKKSNKILGASMICENSSEIIHLIQLAVDLEVEYTYLRDRVYAHPTMTEAL
                     NDILSPNMIKEV"
     gene            3488..4201
                     /locus_tag="OE968_001736"
     CDS             3488..4201
                     /locus_tag="OE968_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017208807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF434 domain-containing protein"
                     /protein_id="HCP7219017.1"
                     /translation="MNKISKRGFDDSDKRWFSSKELTRLIKAKEEIEWLLNRDYKIDP
                     VVTFVGDRYQFSIRQRDALKRAVCTDEKNIIRQSKRLSLDKIKEDTVNIDGFNLIISI
                     EVGLSGGTLVIGSDGNIRDLAGLRGTYKIIDKTEEALNLIGKFFNKYNAQNLKFYLDA
                     PVSNSGNLKYRILEHAKTWGIETEVELVKNADVVLEKLDRVVSSDAVIVDKCISYFNV
                     ARGIIEEYIKECNIINLNK"
     gene            4319..5188
                     /locus_tag="OE968_001737"
     CDS             4319..5188
                     /locus_tag="OE968_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HCP7219018.1"
                     /translation="MRGWICVKLTKLNIKKYRAPIYKYALANINLRSAKSTNSSIITV
                     IPQGAKMEVLDEEDDWIKVMYNSQEGYVYKELVSVSEYAWSNLNLREDKSTTSNIITV
                     IPEKSRVEVLQVDGDWSKVVYDDKIGYVFNYFLSIDGNKPNELDYKYFYTDMIKFVNE
                     NNIKSTSDYLIVTDLRNKYTYIFKKDNGGWGQLYKWQCTIGKPETPTITGIFYISGRK
                     PSFGTDEYSVKYATRIKGGYYYHSVLYDSTGSYIIDGRLGEALSHGCIRLSTENAKWI
                     YDNIPDTTTVIIH"
     gene            complement(5343..6488)
                     /locus_tag="OE968_001738"
     CDS             complement(5343..6488)
                     /locus_tag="OE968_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HCP7219019.1"
                     /translation="MSIYYVPPINLLGKGCLNEAKDSIKSLGTKKAFIVSDKFLVSNG
                     TVKKVTDILSQIDIDFVVYDEVKQNPTVTNVNKGLKILKSENCDFVITIGGGSPQDCG
                     KAISILATNGGDIRDYEGINKTSKKCLPIIAITTTAGTSAEVTINYVITDEDRHVKMI
                     MVDTNSLATMTVNDPELMISKPSNLTAATGMDALTHAIEAVVANGAYDVTDSTALYAI
                     KQIFKYLPRAVKNGNDIEAREQMCYACFLNGIAFSNAGLGNVHAMAHQLGGLYDLPHG
                     VCNAMLLPIVEEENAKSAPAKFRPIAEVIGMDVNNKSDKECVDFVIDKIKALSEEVGI
                     PKSLKDVGVDNPNFELLAENSMKDACAGANPVFFDKDKIIELFMKIS"
     gene            complement(6821..7597)
                     /locus_tag="OE968_001739"
     CDS             complement(6821..7597)
                     /locus_tag="OE968_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HCP7219020.1"
                     /translation="MTSDNHRPTARILDILEALAESENGYTLTEIADVINAPKSSIFP
                     IVHTLNARKYITIDKNTSKYSIGIRSYTLGSSFFEKRTIFNYIIDEMTNIVNSCSETC
                     QLGILDNNEVLYIGKVDSPEPIRLISYVGKKIPANCTGLGKALLCDFDKEKLISLYPD
                     GLKGFTEKSITDFDVLYDQLLEVQRTQIASECEESMEHLKCLAVPIRKNGCIRAAVSV
                     TLPLFRANDEKIELIKKLLLNAQKNIQSMMEERNEDIVIN"
     gene            8179..9153
                     /locus_tag="OE968_001740"
     CDS             8179..9153
                     /locus_tag="OE968_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-keto-3-deoxygluconate permease"
                     /protein_id="HCP7219021.1"
                     /translation="MIMDFIKKIPAGMMIVPMFIAAFINTFCPDIVQIGSFTTAVFSS
                     VGSATIIGVQLVCLGTQLQFREMPKVLKRGGILLGSKFAIGALIGILIGKLFGMDGVL
                     GLTTLAVISAVTNSNGSIYLSLMTSYGDETDCATMSLLTLNDGPFFTLIALGTSGLAN
                     VPLLSLLAAIVPILVGMIIGNFDKKMKEFLEPGCNLLVPFVGFALGSSINLASILKGG
                     LSGVLLGLISVFVGGIFIVFCDKFIGKRPGYAGWAVATTAGNAIAVPAAVALVDPSWQ
                     PYVATATTQVAAAVVVTAILVPLITSWWAKKYGCPKFPKQNEDGTITA"
     gene            9251..9556
                     /locus_tag="OE968_001741"
     CDS             9251..9556
                     /locus_tag="OE968_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HCP7219022.1"
                     /translation="MINAVIIDEKDNVAVAIEAIAKGSEISFKLKDKTVKTITALDDI
                     TIYHKLAIKDMAKGDKVTKYGEHIGEANQEIKSGQHVHIHNVRSVREDLDKQVMTNI"
     gene            9712..10872
                     /locus_tag="OE968_001742"
     CDS             9712..10872
                     /locus_tag="OE968_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HCP7219023.1"
                     /translation="MKFYGYKRPDGRVGIRNHILILPTSVCASDTTRIIASQVQGAVT
                     FNNQNGCSQVHSDQQLTMDVMAGYAANPNVYGVIVVSLGCENCQNDLVVDAIKERTNK
                     PIKTLVIQEEHGTLKTIEKAVRYAREMAQEASLLRKEEFPISELILGTECGGSDPTSG
                     LAANPLIGELSDKLVDLGATSILSETTEFIGAEHILARRAVNEEVKEKILHIVHRYEN
                     SLKLVGEEVREGNPSPGNIAGGLTSLEEKSLGCIHKGGHRQISEVYDYAKQIDKKGLV
                     IMDTPGNDASSVAGMVAGGAQIVVFSTGRGTPSGNPIAPVIKITGNKITFANMEDNMD
                     FDASPVIYGPQTMEELTDDLLNMVVDVANGKQSKAESLGYTEMAIARVCNYV"
     gene            10922..11824
                     /locus_tag="OE968_001743"
     CDS             10922..11824
                     /locus_tag="OE968_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarylacetoacetate hydrolase family protein"
                     /protein_id="HCP7219024.1"
                     /translation="MKFVSFTEGENECKRTGVFSKDELFIIDVNSLNLSRNFKDLNEL
                     IQNVSSEDIIKLKTIINESTFYNYDVFKRERCTVHVPIEKPIHDILCVGVNYKDHLEE
                     TQTHFDDSFEEPQKTVYFTKRVTKAIGPEDEIDGHFEINNQLDYEVELGVVIGKTGVN
                     IRKEEVEDYIFGYTVINDISARKLQKEHVQWFRGKGLDTFTSLGPCILHKSAVPFPIK
                     LKVCSRVNGEERQSSNTGLFISDVSDIVSELSKGMTLEAGDIIATGTPSGVGMGFSPP
                     RYMSSGDVVECEIESIGILKNYIK"
     gene            11904..12797
                     /locus_tag="OE968_001744"
     CDS             11904..12797
                     /locus_tag="OE968_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HCP7219025.1"
                     /translation="MKAEFLTPVVTIFDEEGNLDKEGNKKVYDHLIDGGVDGLVIMGS
                     TGEFFNMSMDMQKELIDLVTSHVNKRVKVFIGTSRMCINESIELSNYAHNSGADGVMI
                     ISPYYFSLDDDSIELFYSEIAKNTEAEIYLYNYPDRTGYDLSPELTLRLARKHKNIVG
                     YKDTVTLMGHTRDLINTMKIEFPEFKVYSGYDENFIHNLMSGGAGCIGGLSNLIPEVC
                     SKWAEAYNNRDMEKVIEIQKYINKAMDFYLITNPFIPAMKKAMNIRGLQISDYMTAPF
                     VKPNEKQVCEIKKLMNELNIC"
     regulatory      12850..13031
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            13259..14389
                     /locus_tag="OE968_001745"
     CDS             13259..14389
                     /locus_tag="OE968_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HCP7219026.1"
                     /translation="MKFKSNVLKQFFLIAMVIFMVGGLIGCSKSDKENKQASTGKKLE
                     LKYASGFSVEDLEDGIKKVTDGDNRELILIPKKIKIPEKYKNANIVRTPVDNVLIAST
                     TQACSLRTIDELDSIKAVTTEEQYWTIKEIKDLMKDGKIHYVGSNLAPDYEKIVDLNP
                     DLTIVSSGLSEADTKFIDKLKELGLNYVVDNEYKEQNPFGRMEWTSLIAAFYDKEDMA
                     TSELNKTVQKVEEVSKKIKNKAKPKVVWASVYEGSAYIAPKDSYVDNMIKMAGGINAC
                     ASIDSNEGRVSIEQLHEVAKDADIFVYSSSSDYAPNLDSIKSSAPVLADLDVVKNGNL
                     WVFAPDYYQSVDKTDELIVDLVEMFHPGTTGEKIKHYINYDK"
     gene            14461..15486
                     /locus_tag="OE968_001746"
     CDS             14461..15486
                     /locus_tag="OE968_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HCP7219027.1"
                     /translation="MDFINKMRIRNTTIFIVLIISMILTFLVCVAFGSVKIEFKEVID
                     VVLRGMDNTEHYKIIYNIRIPRVLATMVGGACLAVSGILLQIFFKNPIVEPYILGVSS
                     GSTLSVALMILGGYTLGFESVNSMSIFVAAFIGALIVMSIVILFANKVKNITTLLIIG
                     IMTGYVCSGITNVLQSFANSDKLKEFTMWSMGSFSGFTWEKVEILIIVGILGLLMTVF
                     IIKPLNAFLLGEEYAKSIGINIRFFRVLIVFISSILAAIVSAFAGPIGFIGLAVPQIS
                     KMIFKTSDNRVLIPVVIFLGSIVTALCDLISRVILSPVELPISTITSLLGAPIVVMLL
                     VKRKDRA"
     gene            15489..16685
                     /locus_tag="OE968_001747"
     CDS             15489..16685
                     /locus_tag="OE968_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCP7219028.1"
                     /translation="MLKTNNLSVGYNNKVVISNINVEVKNGEILCLLGSNGAGKTTLL
                     RSLSKLISPIKGEIYLNGVNINCISRKALSKKMALVLTNRLLGDLMTVQDIVNIGRYP
                     YTGFFGSLSKKDLIMVDEALESVDALHLKKRYFDELSDGEKQKVLVARALVQEPEIII
                     LDEPTTHLDIKHRLELINILKKLSKEKSISVILSLHEIDIALKSCDKVALIKNNKVIA
                     YGQPEDVVDEDIINSLYELDDKNFNSLLGSVEISNKSKNEVFIIGGGGKATPIYRAFT
                     KKGIGLYSGIIHENDIDYEIGRTMGIKMFTENPFEPISDESFNLAIRNLNDSKIIIDT
                     GFSVGETNKRNIDIIKEALKLDKKVYSFRNRDESKKYYDSLDSKIEHIDKVSQIINSA
                     DINNLL"
     gene            complement(16813..17538)
                     /locus_tag="OE968_001748"
     CDS             complement(16813..17538)
                     /locus_tag="OE968_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HCP7219029.1"
                     /translation="MKTISKQELEKTLEKHYLWLKNNNAGEKADLKELRLENMDLRGY
                     CLSNIDFSWSDLINLNLEKADLENSIFNNSYLSDCSLKNSILKNADLSGASFRFCDLS
                     NSDIRGANLENSNLEHATLNGVISDESTRFFKLYCPETGAFIGYKKCFNFRMVQLLIP
                     SDAKRVSATSNACRCDKAKVLSITSIDGKESFKSARAYADENFIYRVGETIVAEDFNE
                     NRWKESTTGIHFFLTREEAIGYL"
     gene            18016..20115
                     /gene="nrdE"
                     /locus_tag="OE968_001749"
     CDS             18016..20115
                     /gene="nrdE"
                     /locus_tag="OE968_001749"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HCP7219030.1"
                     /translation="MNWIELNNQVIIKNEQGKYQLEKDKEALSSYIEEFIQPKLRKFN
                     NLEERLKYLIDEGYYSKEVINQYSIDVIKNIYDMIDKHKFEFQSYMSANKFYQNYALK
                     SNDGKEILETYNDKVLIVALTLGNGDKDLALNLADKIVKQEFQPATPTFLNAGRKRAG
                     EMVSCFLLSVEDSTEGISYAISSSNHLSKIGGGVALNLSKLRASGESIKDIEGAAGGV
                     VGVAKMLEQSFSYFNQMGARQGSGAVYLTVFHPDFELLMDTKKINADEKIRLATLSLG
                     AIIPDKFMELAEKNEVAYAFYPHTVYKKYGVSLDEIEMDEWYDKLVNDSDIRKKEINP
                     RQMLTKIAQMQQESGYPYVVYIDTANREHTLKDVGIIKMSNLCCEIFQYQTPSEIEGY
                     GGKNEWGQDISCNLGSLNIANVMDNKTIESTVETAIRALSFVADSTDIKPVPTVSNSN
                     SKSHSIGLGAMNLHGYLVRENILYTSDDAIDFSNVFFAMVRYYSIKASMKIAIERNQT
                     FEGFDKSEYVKGRNSKVLSKYYEQSYLPKSEKVRALFEGIYIPTKEDWTKLLDEVKEK
                     GIYNAYLMAVAPTQSISYVQNATSSIMPITEPVEVRTYGDSTTIYPMPFLTNDNMLYY
                     QSAYRMDMRKVIDLVATVQNHVDQGISTTLFVTDEKTTRDIARHYIYAYKKGLKSLYY
                     TRTKMTRDTHECLVCSV"
     gene            20127..21098
                     /gene="nrdF"
                     /locus_tag="OE968_001750"
     CDS             20127..21098
                     /gene="nrdF"
                     /locus_tag="OE968_001750"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HCP7219031.1"
                     /translation="MTFNLHKIHNAVNWNREEDGFTQAFWEQNVKQFWLPEEISVSKD
                     IKVWNELSNKEKELYKKVLGGLTLLDTKQGNNGIPSMMSLTENLQRKAVLSFMGTMEE
                     IHAKSYSSIFMTLLSNLEIDELFEWIETEPTLQRKADLVLAQYENTTNQEGLYLSMVT
                     SVFLESFLFYSGFFYPLYLSGQGKMVASGEIISLILRDESLHGKYIGLLAQEIYDSFD
                     KMDKEMLEEKMYSILYSLMENEIEYTNVIYRESGLEKEVVNFLKYNANRALENLGFEK
                     LYTVDAINPIVLNGLSTETKTHDFFSTKGNGYQKGVYEELEDEDFII"
     gene            21174..21800
                     /locus_tag="OE968_001751"
     CDS             21174..21800
                     /locus_tag="OE968_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HCP7219032.1"
                     /translation="MKYEWRKRDKELYLPKKNPVIVEIPEQKFIMLKGSGDPNSKEFT
                     EAIGVLYSLAYAIKTMPKKGIVPEGYFDYTVFPLEGIWDKGEKSKGLDVLIKEDLIYT
                     IMIRQPDFVTQDLLDKATDIVKKKKPHNLLEKVRFGSINEGLCVQMLHIGSYDNEPES
                     FDIMNEFCKKNKLIRKSYTHREIYISDARKVSPESLKTVLRFEVEREV"
     gene            22195..22824
                     /locus_tag="OE968_001752"
     CDS             22195..22824
                     /locus_tag="OE968_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219033.1"
                     /translation="MNKYLLINPVAERMYGEKFHLIKANLIKKGYIITECEPQLEYVK
                     KQYKEYTKKTENTMLDCRCPESISLLKRNNLINNFEVPMIEPILVRTCRVLYDKYIKS
                     KDDMLVVTCPCTQLRDFASEKFKDKGNAMFYTWKEFAEQEGVKSLGKIDESPIPLGYF
                     KDTFEKVLEVSSEDEILSEIQKIRNGFEDKYDIVEMFYCKDGCNNGDGL"
     gene            22825..23607
                     /locus_tag="OE968_001753"
     CDS             22825..23607
                     /locus_tag="OE968_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCP7219034.1"
                     /translation="MVNKFNNKFLRLVKSVLIFFIILLLWKITNYLGIWSDYILPSPE
                     KVYSTFLNMISDGSIFINVYASMKRVLIGFAISTAIGVPLGIFFGIYSGVYEYFKSLI
                     NFLRNTPPLALIPMLILWFGIGEESKIIIIVLASFFPIFTSTLKGIKNCDSKLIEVGR
                     VFEFSKLQIIFKIIIPNAILDIAVGLKLALGYSFRAIIGAELVAASSGLGYLISDGKE
                     MSRTDVVIVGIIVIGLLGIITDYIFSIIVKKVSKGKMVEAYE"
     gene            23600..24478
                     /locus_tag="OE968_001754"
     CDS             23600..24478
                     /locus_tag="OE968_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCP7219035.1"
                     /translation="MNNLVCDSGYIIRNLYKSYKVDNKEHVVLSDISLNIDRNHITVI
                     LGESGCGKTTLLRAIASLEGINSGEIRFINDNKEYRPNVGFVFQESRLMPWLNVSENI
                     AFHNQRKNTILNKVLRKFKHNKRIRSKIINDNFRSLETNDNLNKSNKYNRKSNIDVEK
                     YLKMMNLQKFKNSYPNELSGGMAQRVSIARALSFNPDMLLMDEPFSALDYFTRIDMQN
                     EVIRIHKSTNKGVIFVTHDIDEALKIGKKIVVFTDERKVKEFNIEDGYNRDLTSDYYI
                     KLKKDILMTMKSNKGI"
     gene            24511..25470
                     /locus_tag="OE968_001755"
     CDS             24511..25470
                     /locus_tag="OE968_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NrtA/SsuA/CpmA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HCP7219036.1"
                     /translation="MKLKKLLIGITILTLATASLAGCAKKNNGEKLSEINLTYVKSPL
                     NVPSIIQKQDDLFGKEFKKDNIKVNFHEITTGPEQTQALAAGEIDFLHALGGTSALIA
                     ASNGVELKILNTYSRSPKGFMILTNNNSIKSAADLVGKKVAGPKGTILHQVLISALDK
                     EGLSMDDVEFVNMGIPEASAALSDGSVDAALIAGPAALKAMKSGSKLVANGEGLVDGI
                     IVTAVSTDFAEKHPEIVERFMKVEKETLEYVNNNFDEAMEKVAKEVDLSLEETKELYA
                     WYDFSLDITDKDISSLEDTQDFLIKNKLQEKKVNIKELIYNAK"
     gene            25784..26476
                     /locus_tag="OE968_001756"
     CDS             25784..26476
                     /locus_tag="OE968_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011987369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCP7219037.1"
                     /translation="MSYKVYIVEDDISISTLLKDYIEKYGFEVIVEENFDDIMITFES
                     FKPHLVLLDVNLPKFDGFYWCRCIRQQSNLPIIFISARDGNVDQIRALESGADDYITK
                     PFYYDVVMAKIKSHIRRVYGEYSPKIDERIVELDGLKFYPERLELELNGENLIITKKE
                     GILIECLIKRYPKVVSRDYLLEKIWDDIEFVEENTLNVNVSRIRKRFEELGIDNAVQT
                     VRGLGYKLNKNW"
     gene            26486..27490
                     /locus_tag="OE968_001757"
     CDS             26486..27490
                     /locus_tag="OE968_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HCP7219038.1"
                     /translation="MKLFLKDYKGYIFIYYIGIVMTIIYCNLMKFISFGESLYILLFS
                     SFILLCFLIYKYYKNREVYNLFEKGVHSLEESFLYLGSSFLGRNISVILKQQHKLYQS
                     MIQEHKKIHSEHLTFINQWIHQMKTPISVISLQLQDYEGEEVTENIRKEIDRLNKGLD
                     MAMHFARADNFQKDFIVEKAKLNEIVSSIVNEEKRLFIKSGMIPKIQVDKFTYVYTDV
                     KWMKFIIGQLITNGVKYSKDYSNYLTIKSEENNKYVILSIIDEGIGIVSKDLKRVFAP
                     FFTGENGRKFGESTGMGLYLVKKVCDDLGHKVSIKSEVGKGTEVSIYFNKGVNSLIKM
                     "
     gene            27738..28589
                     /locus_tag="OE968_001758"
     CDS             27738..28589
                     /locus_tag="OE968_001758"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HCP7219039.1"
                     /translation="MSLDVIFILKSVIIAIVEGLTEFIPVSSTGHMILVGNLIDFKGQ
                     FAEMFEVVIQLGAILAVVVLYWKKIKDSVIEFFKFIFTGGKEGKIGFRFGMNVIIGCI
                     PFAIIGVLFYDNIKSLFNLQSVIIGFIVGGILLLVVETLFRKKNHSTDNIDKITPIQA
                     LKVGTLQVLSAWPGMSRSASTIMGGWIAGLNSPTAAEFSFFLAVPAMVASSGKDLFEF
                     DYSIMTPTLWIALVVGFIVAFIVSIIVMEKFVNFLKKKPMRVFAVYRIIMGVVLAVLA
                     FTNIISV"
     gene            28693..29439
                     /locus_tag="OE968_001759"
     CDS             28693..29439
                     /locus_tag="OE968_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001637630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCP7219040.1"
                     /translation="MKILTVNNLSKVYGKKIIFNALNDINFSIEDGEFVGIMGPSGSG
                     KTTLLNMISTIDKPTTGTMELKGKNPLLLRGEELALFRRRELGFVFQDFNLLDTLTIG
                     ENIVLPLTLDKVSVKEQDERLNEVSTILGIKDLLGKRTFEVSGGQAQRTAIARALINN
                     PSILLADEPTGNLDSKSSKVVMELFQKINKENKVTTMMVTHDPLAASYCSRILFIKDG
                     SIYNEIYKGSSREQFYQEIMDVLTLLGGDN"
     gene            29439..31355
                     /locus_tag="OE968_001760"
     CDS             29439..31355
                     /locus_tag="OE968_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCP7219041.1"
                     /translation="MNIKQFAINNISRNIKAYLGYLASIVISSSLLFSFIMFTSHPDL
                     DVSQFPDYLKEGLKMSKIIAYLFLFFFVFYSVSVFLKSRYKEFGILYITGISKRQVMK
                     LIFIENMIINIVSSVIGIIIGLIFAKIFLVVMSTFLELSPLKFYIPFNAILSTLIYFM
                     ILAVLTSIFTSFIVKENQVLKLLKGTKTPKPEPKTSLMLAILSICLFIIAYYNAITST
                     DQYTTYLRLVPVTSLTIVATYLFFSQFSVFFMKKLKLNKRFYRKNTNMLWISNLIYKV
                     KDNARIFFLITITSAVAFTAIGTVYSFWKDVERQINLIYPNTIYYSTMTLHNDPKKPD
                     SKEKDKERMMFIENNLKKENVDYTRINGEFKTVFPKKSDFNVRIMKESKYLEITETIG
                     VKPISFEDNECISLLSSSLPGNKNVKENIIVGNRGLKVAKQVEECVMPAYYKNMYVVK
                     DNFYDSIESKFIVDRFTAFEVEDSSKTIEICREFENKFNNESGMQPYLFFSKELMIGT
                     GKLMYSTFIFLAIFIGLIFFVTTSSFLYNKFYMDCQVDKKKYEQLNKLGMTYNEIKKA
                     STIEIGIVFLFPYVVAVIHSIFALTALKNSFDIEVASSAVLVMGSLFLVQIVYFLIVR
                     NNYLKEIRLNLVNF"
BASE COUNT        12214 a         3317 c         5555 g        10428 t
ORIGIN      
        1 taaataaaga aaagaggaga ataaaatgta caacatagat gatatgatat ataattgtcc
       61 agtagaagct ttatcaaata ttttaggtaa aaaatgggtg gctataatta tatggaaaat
      121 acaagaagat aaaaaacgat ttggagagct acaaagagct ataccagact gtagtaagaa
      181 aatgttagtt caacaactag attttttaat tgaacagggg attatagtca accaaaaaaa
      241 gttggttaat aatgttgtag agtcaacata ttttttaagt gaatcaggat tacgattgct
      301 tcctgtcatg gaaaaaatga ttatgtggag caataaaaat ttaaattgtg ataaatacta
      361 aaatttactc tgtaagtaat gaaaatttaa ttaagctatg agtagaaaaa tgtattaaaa
      421 ttacataatt ttttagttag attttaattt agaaatggga ttgtaatatt ggaaataaaa
      481 taaggaggaa ttttaatttg caaaatgtaa atttattttt agtatttata gaaggtatag
      541 tatcattctt ttcaccatgt atactgccaa ttttgcctat ttatttgagt atattgtcaa
      601 atagtagtgt agaaaattta aaagaaggaa agacgagttt tataggaagt tctttattta
      661 aaaatactat attttttgct cttggaatct caacaacatt ctttatattg ggttcatcag
      721 taaaagtatt gagtatgttt tttaatgaaa ataaagattt aataatgttt attggtggga
      781 ttataattat tatcatggga ttattttaca tgggaataat taaatcttca atattgaata
      841 gagaaaaaag atttaatgtt aagtttaaag aaatgaaagc aataacagct tttatattag
      901 gttttacgtt tagttttgga tggacacctt gtattggtcc aatattggca tctgtattag
      961 tcatggtttc aagttcaagt aatcatctta gtgccaatct tttaatagca gtatatacta
     1021 ttggttttat tttgccattc ataattacag ctatgtttta cagtaaacta tttaaaacta
     1081 tagataagat aaaatctaac atggaaatta ttaaaaaaat aggtgggatt atacttatag
     1141 tatcaggaat attaatgatg gtaaatggat ttggaagtat aagcaaacac tttaatacgt
     1201 cacaaaatag taaaattgaa agcaagcaag aagaaaataa gcgagaaaat tctactgata
     1261 aagaagaaaa ttctgatggt aatgatagtc aaaaagactc taataatgac aataatgata
     1321 aagggtctaa tgatgaagat agaataaagt ctattgattt tactttaaca gaccagtatg
     1381 gtaaaacaca taaattaagt gattatgaag gcaaagttgt attcttaaat ttctgggcta
     1441 catggtgtcc tccatgtaaa gaagaaatgc cttatataga acaactgtat aaagactata
     1501 ataaaaataa tgatgatgta gtaattttag gagtagcttc acctaattta ggtagagaag
     1561 gttcaaggga acatgtagtt aacttcttaa aagaacaagg ttatacattc cctgttgtac
     1621 ttgatgaaga tggagcatta gcatatcaat atggaattaa tgcttttcca actacattta
     1681 taattgacaa ggaaggatat gtaactcagt atattccagg agctatggat aaggcaacta
     1741 tggcatcatt tattgaaaat cagagaaata aataaaagta tttaagtata agtttataaa
     1801 tcaatttaag gttacaaaaa agtgcctaat tgtaccacct aaataatctt gttatagtaa
     1861 aagtataaac aatacaagaa agggttgaat tttatatgaa aaaaacattt gatgctataa
     1921 taataggatt tggaaaaggt ggaaaaacat tagcagggga tttggcaaac aggggattaa
     1981 aagtagcttt aatagaaaag tcaaacaaga tgtatggtgg aacatgtgta aatgtggcat
     2041 gtataccaac aaaaagctta gaaaattcag caaacagcgt aaaaacaaag aatataaatt
     2101 cttgggatga agtacaagct gaatatgaga aagctataga taaaaaagaa actttaatta
     2161 caaaactcag agaagctaac tataataaat taaattcaaa tgagaatgta actatattca
     2221 caggaatggg aactttcatt gatgaaaaaa cagttcaagt caaaactgaa aatgaaattt
     2281 atgagttagt agcagataat atatttatta atactggttc aagaccattt atacctaata
     2341 ttaagggaat tgaaaataag aatatagtat atgatagtga gtctcttatg aatctaagag
     2401 ttttacctaa aaaaatgaca attataggag ctggatttat aggtttagaa tttgctggta
     2461 tttatagttc atttggagca gaagttacaa tattaaactc taataatggc attttaccaa
     2521 atgaagatgt tgaggattca gaagaaataa taaaattact tgcaaagaga aatgtaaaaa
     2581 ttgttaataa tgcaaatata aaagagatta aagaagtttc tgaattagca atagtagaat
     2641 atgaagtaga tggtaaatct aaagaattaa caagtaatat gatacttgta gctacaggaa
     2701 gaaaagcaaa cactgaaggg ctagggctag aaaatgcagg tatagaatta aatgaaagag
     2761 gatttattaa agtctcagaa actcttaaga ctaataaaga gcatatatgg gctataggag
     2821 atataaatgg aggtccacaa tttacttata tttcattgga tgattatcgc atagttatta
     2881 atcagttatt tggagataag actagaacaa ctaatgatag aaagaatatc ccaaattcta
     2941 tatttataag tccagcattt tcaagagttg gtcttaatgt taagcaagct aaagaaaagg
     3001 gatatgaagt attagtggca aagatgccag tagaagcaat tccaagagct aaacagattg
     3061 gcaaggcaga tgggtttata aaaatagtga tagataaaaa atccaataag atacttggag
     3121 ctagtatgat atgtgaaaat tcaagtgaga ttatccatct tattcaatta gctgtagatt
     3181 tagaagtaga gtatacatat ttaagagacc gtgtttatgc acatccaact atgacagaag
     3241 ctcttaatga tattctatct cctaatatga taaaagaagt ataacataag tttaatatat
     3301 aaatctaaaa ttatcattat aagtagattt tagaaagagg ctatctcaaa aaatagagat
     3361 aagtctcttt tttactgttt aaataataaa aatatatttt aatggtatta aaaattatct
     3421 taaaaggtga aataatctgt atttaatgta gtacagttat atctttaaag caaggtggtg
     3481 aaatgatata aataagatat ctaaaagagg gtttgatgat agtgataaaa gatggttttc
     3541 aagtaaagaa ttaacaagac ttataaaggc taaagaagaa atagaatggt tattaaatag
     3601 ggattacaaa atagacccag tcgttacttt tgttggtgat agatatcagt tttctataag
     3661 acaaagagat gcattaaaaa gggcagtctg tactgatgaa aaaaatatta taagacaatc
     3721 aaagaggctt tctctagata aaatcaaaga agataccgta aatatagatg gctttaattt
     3781 gataatatcc atagaggtag gattatctgg tggtactcta gtaataggaa gtgatggcaa
     3841 tataagagat ttagcaggtc ttaggggaac ctataagatt atagataaaa cagaagaagc
     3901 tttgaatctg ataggtaaat tttttaataa atacaatgca cagaatctta aattttattt
     3961 agatgctcca gtttctaatt caggaaattt aaagtatagg atattagagc atgccaaaac
     4021 ttggggaatt gaaactgaag tagaattagt aaaaaatgca gatgttgtat tggaaaaatt
     4081 agatagagta gttagtagtg atgcagtcat agttgacaag tgtataagtt attttaatgt
     4141 ggctagaggt ataattgaag agtatattaa agaatgtaat atcataaatt taaataaata
     4201 gataaatata ggtgagaata tataagtata tgtagcaata ttcttagtaa tacaagtaaa
     4261 gtttgaaaat aggagaacga atacatatcg aatttcataa aatgttgtaa aaagacatat
     4321 gagaggatgg atatgtgtga aattaactaa actaaatatt aaaaaatata gagcacctat
     4381 atataaatat gctttagcaa atataaattt gaggtctgct aaatctacca attcaagtat
     4441 cataacagta atacctcagg gagccaaaat ggaagtattg gatgaggaag atgactggat
     4501 taaggtgatg tacaattctc aagaaggata tgtgtataag gagttggtat cagtaagcga
     4561 atatgcttgg agtaacttaa acttaagaga agataaatct acaacttcca atataattac
     4621 agtaattcct gaaaaatcta gggttgaagt ccttcaagta gatggagatt ggagtaaggt
     4681 tgtatatgat gataaaatag gatatgtttt taattatttt ttatcaattg atgggaataa
     4741 accaaatgaa ttagattata agtattttta tactgacatg attaaatttg ttaacgaaaa
     4801 taatattaaa agtactagcg attatctaat tgtaacagac cttagaaata aatatactta
     4861 tatttttaag aaagataatg gaggatgggg acaactttac aagtggcaat gtactatagg
     4921 caagcctgag actccaacta taacaggtat attttatata agtggaagaa aaccttcttt
     4981 tggaacggat gagtattcag ttaagtatgc tactagaatt aaaggtggat attactatca
     5041 ttctgtacta tatgattcaa caggaagtta tataatagat ggcagacttg gtgaagctct
     5101 tagtcatgga tgtataagat taagtacgga aaatgcaaag tggatatatg ataatatacc
     5161 agatacaaca acagttataa ttcattaaga aaaattttga gttttttatt gggataatga
     5221 ttcttaaatt aataggatta tatattaact tctcataaag agtactattt aaaaagtgta
     5281 ataagagagt gctattaaca aaacaaagat attttgaggc actctcttat aaatatacat
     5341 aattaagata ttttcataaa caattctata atcttatctt tatcaaagaa aacaggatta
     5401 gcaccagcac aagcatcttt catagagttt tctgcaagca attcaaaatt aggattatca
     5461 acacctacat cttttaaaga ttttgggatt ccaacctctt cagaaagagc ttttatctta
     5521 tctattacaa agtcaacaca ctctttatct gatttattat ttacatccat tccaataact
     5581 tcagctattg gtcggaattt ggcaggggct gatttagcat tttcctcctc aactattgga
     5641 agtagcatgg cattacatac tccatgaggt aaatcatata aacctcctaa ttgatgagcc
     5701 atagcatgta catttccaag acctgcatta ctaaaggcaa ttccatttaa aaaacaagca
     5761 taacacattt gttctctagc ttctatgtca ttaccatttt taacagctct tggaaggtat
     5821 ttaaatatct gctttatagc atataaggca gttgaatctg taacatcata agcaccatta
     5881 gctactacag cttctatagc atgagttagt gcatccatac cagttgctgc tgttaaatta
     5941 gatggtttgc taatcattaa ttctgggtca tttactgtca ttgtggctag tgaattggta
     6001 tcaaccatta tcatctttac atgtctgtct tcatcagtta taacatagtt tattgtaact
     6061 tcagcagatg taccagcagt agtagttata gctatgatag gaagacattt tttagaagtt
     6121 ttgttgatac cttcatagtc tctaatatct cctccattag tggctaatat agagatagct
     6181 ttaccacagt cttgtggaga accacctcct atagttataa cgaagtcgca attttctgat
     6241 tttaatattt taagtccttt attcacatta gttacagttg gattttgttt aacttcatca
     6301 taaacaacaa agtctatatc tatctgagat aaaatatctg ttactttttt tacagtacca
     6361 tttgaaacta gaaatttatc actaacaata aatgcttttt tagttcctaa tgatttaatt
     6421 gaatctttag cttcattaag acatcctttc ccaagtaaat ttattggtgg tacataataa
     6481 atgctcataa ctaaaatctc cttttatttt cattgatttt tatgtaaaaa tatatatcta
     6541 acaattttca ctaatttact cataatatat cgtatcttag attgagatag ggttgctggt
     6601 tcttatataa gaacttaatt cgtaattacg attatgatta gaatttaaca tagtattttt
     6661 atcatgtcaa taaaaatata aaaaatatta taaaaaaaac aaagttactg tagttaaatc
     6721 agcaactttg tttttatagt ataaatcaaa taaatacatt agtttaaaac aaaattttta
     6781 attattatgt tttgatatct tccatataca gaatattaat ctaatttatt acaatgtctt
     6841 cattacgttc ttccatcatt gattgaatat ttttctgagc atttaagagt aattttttta
     6901 tcagttctat tttttcgtcg ttagctctaa ataaaggcag tgttacacta acagcagctc
     6961 ttatacatcc attttttctt attggtacgg caagacattt taggtgttcc attgattcct
     7021 cacactctga agctatttgt gttctttgaa cttcaagaag ctggtcgtat aaaacatcaa
     7081 aatctgtaat tgatttttct gtaaaacctt ttagaccatc tggatataag cttattagtt
     7141 tttccttgtc aaaatcacat aaaagagctt ttccaagacc tgtacaatta gcaggtattt
     7201 tttttccaac ataagaaata agtctaatcg gttctggaga atctactttt ccaatataaa
     7261 gaacttcatt attgtcaagt ataccaagct gacaagtttc agaacaggaa ttaactatat
     7321 tagtcatttc gtcaattata tagttaaaaa tagttctttt ttcaaaaaat gaagacccta
     7381 atgtgtaaga acgtatccct atagaatatt tggatgtgtt tttatcaata gtaatgtatt
     7441 ttctagcatt aagtgtatga actataggaa agatgctact ttttggagca ttgataacat
     7501 ctgctatttc tgtaagagta tatccatttt cggattctgc taatgcttct aaaatatcta
     7561 atatcctagc tgttgggcga tgattatctg aagtcataaa tttccccctc tttttattaa
     7621 tttaaagtat tagaatatgt tgattttagc acactatacg atattttaca atgtagaaaa
     7681 taaatatgta aatttatata taaataagct cttgatttag atacagatag atattttttt
     7741 agactgtaca ttaaggaata actaatttcc aaaatatacc taaagaaagt aagtgatatt
     7801 tagttatata atttaagtaa atatatgcaa tagttatttt tatatgtaaa tatcaaaata
     7861 ttatgaactt atattttatc tattttttac actgtataaa aactttatag ttttgaatac
     7921 tatataattt taaatacgct gtatttttgc atataaggaa gtcatttgat aatatacaag
     7981 gtattatcag aaagtttgaa aaaattttga caaaaattta ttttttttat tgactcataa
     8041 ataggaaaat gctatcatta attcaaagat tcgtaattaa aaacttagtt cttaaatacg
     8101 aaccgaaacg gccgttagaa ttaaagctaa aaacttaata agagtaatta aatatcatgt
     8161 tttaggagga ttaactttat gataatggat tttattaaaa aaattcctgc aggtatgatg
     8221 atagtgccaa tgtttatagc agctttcatt aatacctttt gcccagatat tgtacaaata
     8281 ggttcgttta cgacagcagt attttcaagt gttgggtctg caactataat tggggttcaa
     8341 ctggtatgct tgggaactca gcttcaattt agagaaatgc caaaagtttt aaagagaggt
     8401 ggtatacttc ttggttctaa atttgctata ggtgctttga taggtatact tataggaaag
     8461 ctatttggaa tggatggtgt ccttggtctg acaacattgg ctgttataag tgcagttaca
     8521 aatagtaatg gtagtatata tctttcattg atgacttcat atggagatga aacagattgt
     8581 gcaactatga gtttacttac tttaaatgat ggaccatttt ttacattaat agctcttggg
     8641 acttcaggtc ttgcaaatgt accattgttg tcattattgg ctgcaatagt gccaatactt
     8701 gttggtatga taataggaaa ttttgacaaa aaaatgaaag agtttttaga gccagggtgt
     8761 aatttactcg taccttttgt agggtttgca cttggtagta gcataaatct tgcaagtata
     8821 ctaaaaggag gtttatcagg agtattactt ggattaatat ctgtatttgt aggaggtata
     8881 tttatagtat tctgtgataa atttatagga aaacgtccag gatatgcagg atgggctgta
     8941 gctacaactg ctggaaatgc aattgctgta cctgctgctg ttgcattagt tgacccatca
     9001 tggcaaccat atgttgcaac agctacaaca caagtggcag ccgcagtagt tgtcactgca
     9061 atattagtac ctcttataac tagttggtgg gctaagaagt atggatgtcc taagttccca
     9121 aaacaaaatg aggatggtac aataacagct taatttatat tacagtgagt tgttggtaaa
     9181 ataataaatt ctttaattag attttaggat attaataaaa ttatattatt tataaaggag
     9241 agcaagaata atgataaatg cagtgataat tgatgaaaaa gataatgttg cagtagctat
     9301 tgaagcaata gctaaaggta gtgaaattag ttttaaatta aaagacaaaa cagtaaaaac
     9361 gattacagca ctagatgata taactattta tcataaattg gctataaaag atatggccaa
     9421 aggtgataaa gttactaaat atggtgaaca tataggagaa gcaaatcagg aaataaaaag
     9481 tggccaacat gtacatattc ataatgttag aagtgttaga gaggatttgg ataaacaagt
     9541 tatgactaat atataaaata atatttatag agttataaaa gttgtattca ttgcttttag
     9601 tgtcaaatag tttttaaata ggtttttagc tgtttgatta gtgagtgtaa taaaaattat
     9661 aatatataaa aattatagaa agtatataga ctattttagg aggaaatcag tatgaaattt
     9721 tatggatata aaagaccaga tggaagagtt ggtataagaa accacatatt aatattgcct
     9781 acgagtgtgt gtgcatcaga tacaactaga ataatagcat cacaagttca aggggcagtt
     9841 acctttaata atcagaatgg atgttcacaa gtacattcag accaacaatt aactatggat
     9901 gttatggctg gttatgcagc aaatccaaat gtatatggtg taatagttgt atctttggga
     9961 tgcgaaaatt gccaaaatga tttggtagtt gatgcaataa aagagagaac aaataagcca
    10021 ataaaaactc ttgtaataca agaagaacat ggaactttaa aaactataga aaaagctgtt
    10081 cgttatgcta gagaaatggc acaagaagct tctttgctta gaaaagaaga atttccaata
    10141 tctgaactta tactaggaac tgaatgtggt gggtctgacc caacaagtgg attagcagca
    10201 aatccattaa taggtgaatt aagtgataaa cttgtcgatt taggagcaac atcaatttta
    10261 agtgaaacta ctgaatttat aggtgcagag catatactag ctaggagagc agtaaatgaa
    10321 gaagtaaaag aaaaaatatt acatatagta catagatatg aaaattcatt aaaattggtt
    10381 ggagaagaag ttagagaagg taatccatct cctggaaata tagctggtgg tttaacaagt
    10441 ttagaagaaa aatcacttgg ttgtatacat aaaggtggtc atagacaaat aagtgaagta
    10501 tatgattatg ccaaacaaat tgataagaaa ggtcttgtta taatggatac ccctggaaat
    10561 gatgcttcat ctgttgctgg tatggtagca ggaggagcac aaatagtggt atttagtaca
    10621 ggaagaggaa caccatcagg aaatccaata gcaccagtaa taaaaataac tggaaataaa
    10681 ataacttttg caaatatgga agataatatg gattttgatg ctagtccagt tatctatggt
    10741 ccacaaacaa tggaagaatt aacagatgat ttgttaaata tggttgtaga tgtagcaaat
    10801 ggaaaacaat caaaagcaga gtcccttgga tatactgaaa tggcaatagc tagagtatgc
    10861 aactatgtat aatctttaag taagaaaata aatacataga attttaataa agggtgagat
    10921 tatgaagttt gtaagtttta ctgaaggaga aaatgaatgt aaaagaactg gagttttttc
    10981 taaagatgaa ttatttatta tagatgttaa ctctttaaat ctcagtagaa attttaagga
    11041 tttaaatgaa ttaattcaaa atgtatctag tgaagatatt attaagttga aaactattat
    11101 aaatgaaagt acattctata attatgatgt ttttaaaaga gagagatgta cggtacatgt
    11161 tcctatagaa aaaccaatac atgatatctt atgtgtggga gtgaactata aagaccatct
    11221 tgaagaaact caaactcact ttgatgatag ttttgaagaa ccacaaaaaa cggtttattt
    11281 tacaaaacgt gtgacaaagg caataggtcc agaagatgag atagatggtc attttgagat
    11341 aaataatcaa ctagactatg aagttgaact tggagtagta ataggtaaaa caggtgttaa
    11401 tattagaaaa gaagaggtag aagattatat ctttggttac actgttataa atgatatttc
    11461 tgctagaaag ttgcaaaaag aacatgttca atggtttaga ggaaaaggat tagatacatt
    11521 tacctcttta ggtccatgta ttttacataa aagtgcagtt ccttttccta taaaacttaa
    11581 agtatgtagt agggtaaatg gtgaagaaag acaaagttct aatacaggat tattcatatc
    11641 agacgtttca gacatagttt cagaactttc aaaaggtatg accttagagg ctggagacat
    11701 tatagctact ggaacacctt ctggagtagg gatgggattt tcacctcctc gatatatgag
    11761 tagtggagat gtagttgaat gtgagattga gagtattgga attttaaaaa attacattaa
    11821 gtaactgttt taatataatt aatattaaag ctaaatctga tgtattaatg aacatattaa
    11881 aataaatttt aggagtttaa attatgaaag cagaattttt gacaccagtt gttacaatat
    11941 ttgatgaaga aggaaattta gataaagaag gtaataaaaa agtgtatgac catcttatag
    12001 atggaggtgt agatggacta gtcataatgg gaagtactgg agagttcttt aatatgtcta
    12061 tggatatgca aaaagaactt atagatttag taactagtca tgtaaataag agagtaaaag
    12121 tgtttatagg tacaagtcgt atgtgtataa atgaatctat agaactttca aactatgcac
    12181 ataatagtgg agcagatggt gttatgataa taagccctta ttatttctct cttgatgatg
    12241 atagtattga gttattttat agtgaaatag ctaagaatac agaggctgaa atatatttgt
    12301 acaattatcc agatagaact ggttatgatt taagtccaga acttacatta agacttgcaa
    12361 gaaaacataa aaacatagtt ggatataagg atacagtaac tttgatggga cataccagag
    12421 atttaataaa tactatgaaa atagagttcc cagaatttaa ggtttatagt ggttatgatg
    12481 aaaactttat acataatcta atgtctgggg gagcaggttg tatagggggg ttatcaaatt
    12541 taattccaga agtttgctcc aaatgggctg aagcttacaa taatagagat atggagaagg
    12601 ttatagaaat tcaaaaatat attaataaag caatggattt ttacttaata accaatccat
    12661 ttataccagc aatgaaaaaa gctatgaata tcagagggtt acaaataagt gattatatga
    12721 ctgctccatt tgtaaaacca aatgaaaaac aagtatgtga aattaaaaaa ttgatgaatg
    12781 aattaaatat atgttaaatc aaccttgcaa agaggtcaac aataaattac aattatctta
    12841 ataaaaatta aattaaaata atactagggt actatattag tttaataggg aaagtgatga
    12901 aaattcacta cagcccccgc tactgtatac ggatacgaaa tcaaaatcca ctgaaattta
    12961 taaaaatttt gggaagggtg atggaggaaa agccgtgagt caggagacct gcccagtatt
    13021 atataagttc aatttagggt ggagattgta atttataata aaatgaagta tcaattcgtt
    13081 tttgtaaagt tgatatatga acttctcctt attaaattag gagaagtttt ttattttatt
    13141 aaaaggttat acttattaaa gatgacttta ggataacttt aataagtata ctttaaaaag
    13201 catatattat taaagttttt tagccactca taaaaaataa gatattggag tgaaagagat
    13261 gaaatttaaa tcaaatgttt taaagcagtt ttttttaatt gctatggtaa tttttatggt
    13321 aggaggtctt atagggtgta gtaaaagtga caaagagaat aaacaagcta gtactggtaa
    13381 gaaattagaa ttaaaatatg ctagtggatt tagtgttgaa gatttagaag atggaattaa
    13441 aaaagtaact gatggagata atcgagaact gattttaatc ccaaagaaga ttaaaattcc
    13501 tgaaaaatat aaaaatgcta atatagttag aacgcctgtg gacaatgtat taatagcatc
    13561 tacaacacag gcttgttctc tgagaacaat agatgaacta gatagtataa aagccgtaac
    13621 aacagaagag cagtactgga ctattaaaga aattaaagat ttaatgaaag atggaaaaat
    13681 acattacgtt ggttcaaatt tagcaccaga ttatgaaaaa atagtagact taaatcctga
    13741 cttaactata gtgagtagtg gtttatcaga ggctgataca aaatttattg acaaattaaa
    13801 agaattaggg cttaattatg ttgtagacaa tgagtataaa gagcaaaatc catttggaag
    13861 aatggagtgg acaagtttaa tagctgcatt ttatgataaa gaagatatgg ctactagtga
    13921 actaaataaa actgtacaaa aggtagaaga agtaagtaaa aaaataaaaa acaaagctaa
    13981 acctaaagtt gtatgggcat ctgtatatga aggaagtgct tatatagctc ctaaagattc
    14041 atatgtggat aatatgataa aaatggctgg tggaataaat gcatgtgctt caatagattc
    14101 aaatgaaggg cgagtaagta ttgaacaatt gcatgaagtt gcaaaagatg cagatatatt
    14161 tgtatactca tcaagttcag attatgcacc aaatttagat tctataaaat ctagtgcacc
    14221 tgtattggct gatttggatg ttgtaaaaaa cgggaaccta tgggtgtttg ctccagatta
    14281 ttatcaatca gtagataaga cggacgaatt aatagtagat ttagttgaga tgttccaccc
    14341 aggtactaca ggtgaaaaaa tcaaacatta tataaattat gataaatagt acagagagga
    14401 cacaaaaaga taggttttat agattttagt taatatagct ttgctaagag gagtatacaa
    14461 atggatttta tcaataaaat gagaataagg aatacaacaa tatttatagt attaattata
    14521 agtatgatac ttactttttt agtgtgtgta gcatttggct ctgtaaaaat tgaatttaaa
    14581 gaagtaatag atgttgtatt aagaggtatg gataatacag aacattataa aataatatac
    14641 aatataagaa tccctagagt acttgcaacc atggtaggtg gagcatgcct agcagtatca
    14701 ggtattttat tacagatatt ttttaaaaac ccaatagttg aaccgtatat attaggagta
    14761 tcttcaggtt ctactttatc agtagctctc atgattttgg gaggatacac attgggattt
    14821 gagagtgtaa attcaatgag tatatttgta gcagctttta taggagcttt aattgtaatg
    14881 tctatagtca ttttatttgc aaataaggta aagaatataa caactctttt aataatagga
    14941 attatgaccg gatatgtatg tagtggtata acaaatgtgt tacaatcatt tgcaaatagt
    15001 gataaattaa aagaatttac tatgtggtct atgggaagtt tttctggatt tacatgggaa
    15061 aaggtagaaa tacttataat agttggtata ttaggtcttt tgatgactgt attcataata
    15121 aaacctttaa atgctttttt actaggagaa gagtatgcaa aaagtattgg cataaatata
    15181 agatttttta gagttttgat agtatttata tctagtatat tagcagcaat agtatcagca
    15241 tttgcaggac ctatagggtt tattggactt gcagtgccac aaatttcaaa aatgatattt
    15301 aaaacatcag ataatagagt tttgatacca gtagtaatat ttttaggcag tatagttaca
    15361 gctctttgtg atttaatatc aagagtaatt ttatcaccag tagaattacc aataagtacg
    15421 ataacatctt tattaggagc tccaattgta gtaatgttat tggtgaaaag gaaggatagg
    15481 gcttagacat gttgaaaact aataatttaa gtgtaggata caataacaaa gttgttataa
    15541 gtaatataaa tgtagaagta aaaaatggag aaatactatg tcttttggga agtaatggag
    15601 ctggaaaaac taccctatta aggtccttat ctaaacttat atcaccaata aaaggtgaaa
    15661 tatatttgaa tggtgtaaac ataaactgta tatcaagaaa agcattatca aaaaaaatgg
    15721 ctttagtact tacaaataga ttattaggtg atttaatgac tgtacaagat atagtcaata
    15781 taggaaggta tccatataca ggattttttg ggagtctatc taagaaagat ttaataatgg
    15841 tagatgaagc attggagtct gtagatgcct tacatttaaa gaaaagatat tttgatgaac
    15901 taagtgatgg agaaaaacaa aaggtgttgg ttgcaagggc tcttgttcaa gaaccagaaa
    15961 taattatatt agatgagcct acaactcact tggatataaa acatagattg gaactcataa
    16021 acatactgaa aaaattaagt aaagaaaagt caatatcagt aatactttca ttgcatgaaa
    16081 tagacatagc attaaaaagt tgtgataaag ttgctcttat aaaaaataat aaagtcatag
    16141 cttatggtca gcctgaagat gtagtagatg aggatattat aaattcgctt tatgaattgg
    16201 atgataaaaa ctttaatagt cttttaggtt cagtagaaat tagtaataaa tctaaaaatg
    16261 aagtttttat aattggtggt gggggtaaag caacaccaat ttatagagct tttactaaaa
    16321 aaggtatagg tctgtattct ggaataatac atgaaaatga tattgattat gaaattggta
    16381 gaactatggg gataaagatg tttacagaaa atccatttga gcctataagt gatgagagtt
    16441 tcaatttggc tattagaaat ttaaatgatt ccaagattat aatagataca ggatttagtg
    16501 taggagagac aaataagagg aatatagata ttataaaaga ggctttaaaa ttggataaaa
    16561 aagtttattc ttttagaaat agagatgaga gtaagaagta ttatgacagt ttggatagta
    16621 agatagaaca tatagataaa gtttctcaaa taatcaatag tgcagatata aataatttat
    16681 tataatttat gaaataaaat gtacttatgt gctatagaaa aaagagtata gattataatt
    16741 tttttgaaat tacaatctat actcttttgt tattttgttt atgtatttat atatttataa
    16801 aactttagca ttttatagat aaccaatagc ttcctctcta gttaaaaaaa agtgaatccc
    16861 tgtagtcgat tctttccatc tattttcatt aaaatcttca gctacaatcg tttctcctac
    16921 tctatatata aaattttcat cagcatatgc acgagcactt ttaaaagatt ctttaccatc
    16981 tatactagta attgacagta cttttgcctt atcacatcta caagcgtttg atgtagcaga
    17041 cactcttttt gcgtcgctgg gtattaataa ttgtaccatt ctaaaattaa aacatttttt
    17101 atagcctata aatgctcctg tttcaggaca atacaattta aaaaaacggg tactttcatc
    17161 tgatattact ccatttaaag tagcatgttc taaatttgaa ttttctaaat tagctcctct
    17221 aatatctgag ttagataagt cacaaaatct aaaacttgca ccacttaagt ctgcattttt
    17281 taatatagaa ttttttaatg aacaatccga aagataagaa ttattaaaaa tagagttttc
    17341 taaatctgct ttttctaaat ttaaattgat aaggtcagac cacgaaaagt caatattact
    17401 taagcagtat cctcttaagt ccatattttc taatcttaat tcttttaaat ctgccttttc
    17461 tccagcatta ttgtttttaa gccataaata atgtttctca agtgtttttt ctaattcttg
    17521 tttagaaata gttttcatta aaatcacctt cataaattta tttttatata tgtagtagca
    17581 aaatagtcat atatttaatt atataacaat aaataaaaaa cttctaaata atatataaaa
    17641 tatcatcttg aaagtacttt tttcaatata tcagaatata tttttaagct atttagagat
    17701 aatttaaatt tttaaacagg acataataag cttgtattgt tttatatttg agttgataaa
    17761 aatttcttta aataaaaata atgtcaatta taaagtaata aaagtttaga tataaaaaaa
    17821 tttgtgtata tactatatgt agtatataat agataaagca ctgactatat gtagtgcttt
    17881 tgtttttgaa aaatacttat tgcatttcta taattataga ttaattttgg gatttcaact
    17941 gataagtacc aaaagaaata ataagcaaat taagtgaaat tatggcacaa gattatgtta
    18001 aaaggacggt aaataatgaa ttggatagag cttaacaatc aagtgataat taaaaatgaa
    18061 caaggcaagt accaattgga aaaggataag gaagccttaa gtagttacat agaagaattt
    18121 atacagccaa agttgagaaa atttaataac ctagaagaaa gattgaagta tttaatagat
    18181 gaaggttatt attcaaaaga agtaataaat cagtatagca tagatgttat taaaaatata
    18241 tatgatatga ttgataaaca taagtttgaa tttcaatcat atatgagtgc aaataagttt
    18301 tatcaaaatt atgcattaaa gagcaatgat ggaaaggaaa tattagaaac atataatgat
    18361 aaagtgttaa ttgtagcttt gacactagga aatggtgata aagatttagc tttaaacttg
    18421 gcagataaaa tagtaaaaca agaatttcaa ccagctacac ctactttttt aaatgctgga
    18481 agaaaaaggg ctggagaaat ggtatcatgt tttttactat ctgtagaaga tagtacagaa
    18541 ggtatatcat atgctatatc ttcatcaaat cacttatcaa agattggtgg aggagttgca
    18601 ctaaatttat ctaaacttag agcatctggc gaatctatca aagatataga aggtgcagct
    18661 ggaggtgttg ttggagtagc taaaatgtta gaacaatcat ttagttactt taatcaaatg
    18721 ggagctagac aaggttctgg tgcggtgtac cttactgtat tccatcctga ttttgaattg
    18781 ttgatggata ctaaaaagat aaatgcagat gaaaaaataa ggcttgctac attatcatta
    18841 ggagctataa taccagataa atttatggag ttggcagaaa aaaatgaagt agcatatgca
    18901 ttttatcctc atactgtgta taagaaatat ggagtttctc ttgatgagat agaaatggat
    18961 gagtggtatg ataaattggt taatgatagt gatataagaa aaaaagaaat aaatcctagg
    19021 cagatgttga caaaaatagc acagatgcaa caagaaagtg gatatccata tgtagtgtac
    19081 atagatacag ctaatagaga acatacatta aaagatgttg gaattattaa aatgtctaac
    19141 ttatgttgtg agatatttca atatcaaaca ccttcagaaa tagaggggta tggaggaaaa
    19201 aatgaatggg gacaagatat aagttgtaac ctaggttctt taaacatagc taatgtaatg
    19261 gataataaaa ctatagaaag tacagttgaa acagcaataa gagcactgtc atttgtagca
    19321 gatagcacag atataaaacc agtgccaacg gtaagcaata gtaacagcaa gtctcattct
    19381 ataggattag gagctatgaa tttacatgga tacttagtaa gagaaaatat tttatatact
    19441 tcagatgatg ctatagattt ttctaatgta ttttttgcaa tggttagata ctattcaatt
    19501 aaagcttcta tgaaaatagc tatagaaaga aatcaaactt ttgaaggatt tgataaatca
    19561 gaatatgtta agggaagaaa tagcaaggtt ttatcaaaat actatgaaca atcttatcta
    19621 cctaagtcag aaaaggtaag agcattattt gaagggattt atataccaac aaaagaagac
    19681 tggacaaaat tattggatga ggtaaaagaa aaagggatat ataatgcata tttaatggca
    19741 gtagcaccaa ctcaaagcat tagttatgtt caaaatgcta catcaagtat aatgccaatt
    19801 actgagccag tagaagtaag aacatatgga gactctacta caatatatcc aatgccattt
    19861 ttaacaaatg ataatatgtt gtattatcaa tcagcataca ggatggatat gagaaaggtc
    19921 atagatttag tggcaacagt tcaaaaccat gttgaccaag gtatatcaac aacactgttt
    19981 gttacagatg aaaagacaac tagagatata gctagacatt acatatatgc ctataaaaaa
    20041 ggtttgaaaa gtttatatta cacaagaaca aagatgacaa gagatactca tgagtgtcta
    20101 gtgtgttcag tatagggaga gaaattatga catttaattt acataaaata cataatgcag
    20161 ttaactggaa tagagaagaa gatggattta cacaagcttt ttgggaacaa aatgtaaaac
    20221 aattttggct tcctgaagaa atatctgttt ctaaagacat aaaggtatgg aatgaactaa
    20281 gtaataaaga aaaggaatta tataaaaaag tattgggtgg tttaacatta ctggatacaa
    20341 aacaggggaa taatggaata ccatctatga tgagtttaac agaaaaccta caaagaaaag
    20401 ctgtcttgtc ttttatgggg actatggaag aaatacatgc aaaaagttat tcttctatat
    20461 ttatgactct actttctaat ttagaaatag atgaattatt tgaatggata gaaacagaac
    20521 caacattaca aagaaaggct gatttagttt tagctcaata cgaaaatact acaaatcaag
    20581 agggattata cctatcaatg gttacaagtg tatttttaga gagtttcttg ttttattcag
    20641 gattctttta tccattgtat ctatctggtc aaggaaagat ggtagctagt ggagaaataa
    20701 tatcgcttat tcttagagat gagtctttac atggtaagta tataggattg ctagcacaag
    20761 aaatatacga ttcatttgat aaaatggata aggagatgtt agaagagaag atgtattcta
    20821 tactttatag ccttatggag aatgagatag agtatacaaa tgttatatac agagaaagtg
    20881 ggcttgaaaa agaggttgtg aactttttaa aatacaatgc aaatagagct ttagaaaatc
    20941 tagggtttga gaagctatat actgtagatg ctataaatcc aattgtatta aatggtctta
    21001 gcactgaaac caaaacacat gatttttttt caactaaggg taatggatac caaaaaggag
    21061 tgtatgagga attagaggat gaagatttta taatataatt tataattatg acacactgtt
    21121 gtcactttta gcgtgataat atcaatgtat aaaatatata tggaggtatt tttatgaaat
    21181 atgaatggag aaaaagagat aaagagttat atttacctaa aaagaatcct gtaatagttg
    21241 aaataccaga acagaaattt atcatgttaa aagggagtgg agacccaaat tctaaagaat
    21301 ttactgaagc aataggagta ctttattctt tggcatatgc aataaaaacc atgcctaaaa
    21361 aaggaattgt accagaaggg tattttgact atacggtttt tcctttagaa ggtatatggg
    21421 ataagggaga aaaaagtaaa ggcttagatg tacttattaa agaagattta atttacacta
    21481 taatgatacg tcagccagat tttgttacac aagacctgtt ggataaagct actgatatag
    21541 taaagaagaa aaaacctcat aatcttcttg aaaaagttag atttgggtct attaatgaag
    21601 ggctatgtgt tcaaatgctt catataggtt catatgataa tgaaccagaa agctttgaca
    21661 ttatgaacga attttgcaaa aaaaataaac ttataagaaa atcttacaca catcgtgaaa
    21721 tttatataag tgatgctaga aaagtatcgc ctgaatcatt gaagacggtt ttacgttttg
    21781 aagtagaaag ggaagtataa atattttgaa taatttataa gagttataaa aagtgaagtc
    21841 tgttgagact tcattttttg atgcaatttt aaaattaaat ttgatgtttc ataatatttt
    21901 aaaaactttc tacttttatt agtgtgaata actgttgcta ttaaataata atactaatta
    21961 tataagtatt attatataat atttatagat tattatataa atagattatt agtaagatgt
    22021 atgcattatt aattaaaata aattacatat actatttaat atttcattta aaatattaaa
    22081 aaatgtagat aaaaattgtt ttattaagaa aaaattaata tattgacaaa atttaagtgc
    22141 tcatttaaac tattaattga taataatatt caatattaaa taataggagg cgttatgaat
    22201 aaatatcttc taataaatcc agtggcagaa agaatgtatg gagaaaagtt tcaccttatt
    22261 aaagcaaatt tgataaaaaa ggggtacata ataacagaat gtgaaccaca gttagaatat
    22321 gtaaaaaagc agtacaaaga gtatacaaaa aagactgaaa atacaatgtt ggattgtaga
    22381 tgtccagaaa gtataagtct tttaaaaaga aataatttga taaataattt tgaagtacct
    22441 atgatagaac caatattagt aaggacttgt agggttttat acgataaata tataaaaagt
    22501 aaagatgata tgttggtagt aacctgtcca tgtacacaat taagagactt tgcaagtgaa
    22561 aagtttaagg ataagggtaa tgctatgttt tatacatgga aagagtttgc tgaacaagaa
    22621 ggtgtaaaat cacttggaaa aatagatgaa tcaccaattc cattaggata tttcaaagat
    22681 acttttgaaa aagttcttga agtatcaagt gaagacgaaa tattaagtga aatacaaaaa
    22741 ataagaaatg gttttgaaga taagtatgac atagtagaaa tgttttattg taaagatggt
    22801 tgtaataatg gagatggttt gtaaatggtc aataaattta ataataagtt tttaaggcta
    22861 gtaaagagtg ttctgatatt ttttataatt cttttattat ggaaaattac aaattatctt
    22921 ggtatttgga gtgattatat attaccatca cctgaaaagg tatatagtac atttttaaat
    22981 atgataagtg atggttcaat atttattaat gtatatgcaa gtatgaaaag agttttgata
    23041 ggttttgcaa taagtactgc tataggtgtg cctttaggga tattctttgg aatttatagt
    23101 ggagtatacg aatactttaa atctctaata aattttttaa ggaatacacc tccccttgct
    23161 ttaataccaa tgcttatatt atggtttggt ataggagagg aatcaaaaat tataattata
    23221 gttttagcat cttttttccc aatctttaca agcacattga aagggattaa aaattgtgac
    23281 tcaaaactga ttgaagtggg tagagtattt gagttttcaa agcttcagat aatatttaaa
    23341 ataataatac caaatgccat tcttgatatt gctgttgggt taaagttagc tcttggatat
    23401 agctttagag caattattgg ggcagaactt gtagcagctt catctggtct tggatacttg
    23461 atatctgatg gaaaagaaat gtctagaaca gatgttgtta ttgtagggat aatcgtaatt
    23521 ggacttttag gaataattac agattacata ttttcgatta ttgtgaagaa ggtaagtaag
    23581 ggaaagatgg tggaagcata tgaataattt agtatgtgac tctggatata taattagaaa
    23641 tttatataaa agttataaag ttgacaataa agaacatgta gttcttagtg atatctcttt
    23701 aaacatagat agaaaccata taacagtaat tttaggtgaa agtggttgtg gaaagactac
    23761 cttgcttaga gcaattgcat cacttgaagg tataaatagt ggtgaaatta ggtttattaa
    23821 tgataataaa gagtatagac ctaatgttgg ttttgttttt caggagagta gattaatgcc
    23881 ttggttaaac gtaagtgaaa atatagcttt tcataatcaa agaaaaaata ctattttaaa
    23941 caaggtgctt agaaaattta aacacaataa aagaattagg agtaaaatta taaatgataa
    24001 ttttagaagc ttagaaacaa atgataattt gaacaaatca aataaatata ataggaaaag
    24061 taatattgat gtagaaaaat atcttaagat gatgaacttg cagaaattta aaaactctta
    24121 tccaaatgaa ttgtcaggag gtatggcgca gagagtaagc atagctagag ctctttcttt
    24181 caatccagat atgttgctta tggacgagcc tttttcggca ttagattatt ttacaaggat
    24241 tgatatgcaa aatgaagtta taagaataca taagtcaact aataaaggcg tgatatttgt
    24301 aactcatgat attgatgaag cgttaaagat aggcaagaaa atagttgttt tcacagacga
    24361 aagaaaagta aaagaattta atatagaaga tggttataat agagatttaa cttcagatta
    24421 ctatattaaa ttaaaaaaag atattttaat gacaatgaag tcaaataaag gcatttaaag
    24481 aaattaataa tattttaagg agtaaagtaa atgaaattaa aaaagctatt gataggtata
    24541 acgatattaa cacttgcaac agcatcttta gctggatgtg ctaaaaaaaa taatggagaa
    24601 aaactttcag aaataaattt aacttatgta aaatcaccat taaatgttcc ttctataatt
    24661 cagaaacagg atgatttatt tggaaaggaa tttaaaaagg ataatataaa agttaacttc
    24721 cacgaaatta ctacaggtcc agagcaaaca caagctttag ctgctggaga aatagacttc
    24781 ttacatgcac taggtggtac atcagcttta atagctgcat ctaatggagt agagttaaag
    24841 atattaaaca cttatagcag gtcaccaaaa ggatttatga ttttgactaa taataattca
    24901 ataaaatcag cagcagattt agtaggtaag aaggtggcag gcccaaaagg gactatatta
    24961 catcaggtat tgatttcagc acttgataaa gaaggattaa gtatggatga tgtggaattt
    25021 gttaatatgg gtattccaga ggcatcagca gctctttctg atggcagcgt agatgctgca
    25081 ttgattgctg ggccagcagc tcttaaagct atgaagtcag gtagtaaact tgtagcaaat
    25141 ggtgaaggtt tagtagatgg tataatagta actgctgtta gcacagactt tgcagagaaa
    25201 catccagaaa tagttgaaag atttatgaag gttgaaaagg aaactttaga atatgtaaat
    25261 aataattttg atgaagctat ggaaaaagta gctaaagaag ttgatttaag tcttgaagaa
    25321 actaaagaat tatatgcttg gtatgatttt agtttagata taacagataa agacatatct
    25381 tcgcttgaag atacacaaga cttcttaata aaaaataagt tacaagagaa aaaagtgaac
    25441 ataaaagaat taatctataa tgctaagtag aaactatgat aaaataatac taagtaagaa
    25501 atataataaa agtttaagtt accttattaa ggtaactttt tctattttga attagtaatt
    25561 tcaatttatt ttagaatgat tagttgataa taatgattaa ttaatcataa aaagatactt
    25621 ttttatagag ttttattaag atgtctaata atatggttat acttatgaag tcagtaattg
    25681 tgaagttagt aatatgatta aatttatata ttgtaaaaag attataatat attaaaattg
    25741 gactgttata tgatgagtaa ataggtatat taggaggaat tatatgagtt ataaagtata
    25801 tattgtggaa gatgacatat caataagtac attacttaaa gattatattg agaaatatgg
    25861 atttgaagtg attgttgaag agaactttga tgatataatg attacatttg aaagttttaa
    25921 gccacactta gttctattag atgtaaattt acctaaattt gatggtttct actggtgtag
    25981 atgtattagg caacagtcga atttacctat aatttttata tcagctagag atggtaatgt
    26041 agaccaaatt agagctttag aaagtggagc agatgattat ataacaaaac ctttttacta
    26101 tgatgtagta atggcaaaaa taaagagtca tataagaagg gtatatggtg aatattcacc
    26161 taaaatagac gaaagaatag tggagctaga tggattaaaa ttttatccag aaaggttaga
    26221 actagaatta aatggtgaga atctaattat aactaaaaaa gaaggtatac tgattgaatg
    26281 tcttatcaag agatacccaa aagtagtaag tagagattat cttttagaaa agatatggga
    26341 tgatattgag tttgtagagg aaaatacttt aaatgtaaat gttagcagga taaggaaaag
    26401 atttgaggaa ttaggtatag ataatgctgt tcagactgtc cgagggttag gatataaatt
    26461 aaataagaat tggtaaggag aaagtatgaa gttattttta aaagattata aaggttatat
    26521 ttttatatat tatataggca tagttatgac aattatttac tgtaatctta tgaagtttat
    26581 tagttttgga gagagtttat atattctttt atttagttct tttatattgt tatgtttttt
    26641 aatatataag tattataaaa atagagaagt atataatctg tttgaaaaag gagtacattc
    26701 tttggaggag tcatttttgt atttaggaag ctcattcttg gggagaaata tatcagttat
    26761 tttaaaacaa caacataaat tgtatcaatc aatgatacaa gagcataaaa agatacatag
    26821 tgaacattta actttcatca accaatggat tcatcagatg aaaacaccaa tatcagttat
    26881 aagccttcag ctccaagatt atgagggaga agaagtaact gaaaatataa gaaaagaaat
    26941 agatagattg aataaagggt tagatatggc tatgcatttt gcaagggcag ataattttca
    27001 gaaagacttt atagttgaaa aagccaaatt aaatgaaatt gtatctagta ttgtaaatga
    27061 agaaaaaagg ttatttataa aaagtggaat gattcctaag attcaagtag acaagtttac
    27121 ttatgtttat acagatgtaa aatggatgaa atttataata ggtcaattaa ttacaaatgg
    27181 agtgaaatat tctaaagatt atagtaacta cctaactata aaatctgaag aaaataataa
    27241 atatgtaatt ttaagtataa tagatgaagg aattggaatt gtttctaaag atttaaaaag
    27301 ggtatttgcc ccatttttta caggagaaaa tggtcgtaag tttggagaat ctacaggtat
    27361 gggtctttat ctagtaaaaa aggtatgtga tgatttaggt cataaagtaa gtataaaatc
    27421 agaagtagga aaaggtacag aagtttcaat ctactttaat aaaggtgtaa atagtttgat
    27481 aaagatgtaa attatctgtt acaatagggt ttttagttaa ttgtactttt ttattataca
    27541 atttattaaa tgaaatattc atagttaaat aatcaaaatt taagagagtt tatttgcaaa
    27601 ccttacatag atgtaaggtt tgtgtaatgt ttgcagatag ttaaattttc taatctaaat
    27661 tacaattaat ataagaaata acataagaga aataacataa aaaaagaaat tttgtaaaaa
    27721 aggaaggatg tttattgatg agtttagatg ttatttttat attgaaatca gtcataatag
    27781 ctatagtaga ggggcttaca gaatttattc cagtttcatc tacaggtcat atgattttgg
    27841 ttggtaattt aatagatttt aaggggcaat ttgctgaaat gtttgaggtt gtaatacaac
    27901 ttggggctat attagcagta gtagtacttt attggaaaaa gataaaagat agcgttatag
    27961 aattttttaa atttatattt actggtggaa aagaaggaaa gattggtttt agatttggaa
    28021 tgaatgtaat tataggttgt ataccatttg cgattatagg agttctattt tacgataata
    28081 taaaatcatt gtttaattta caatctgtaa ttataggatt tatagtgggt gggattttat
    28141 tattagtagt agaaactttg tttagaaaaa agaatcattc cacagataat atagataaaa
    28201 ttactccaat acaagcttta aaggttggga cattacaagt tttgtctgca tggccaggta
    28261 tgtcaaggag tgcatctact attatgggtg gatggatagc aggacttaat tctcctacag
    28321 cagctgagtt ttctttcttt ttagcagtac cagctatggt ggcttcttca ggaaaagatt
    28381 tatttgaatt tgattattca ataatgacac caacattgtg gattgctttg gtagttgggt
    28441 ttatagtagc ttttattgta tcaataatag ttatggaaaa attcgtgaat tttttaaaga
    28501 aaaaaccaat gagagtgttt gctgtataca gaataatcat gggtgtagta cttgcagtat
    28561 tagcttttac taacataatt agtgtataga aaaaatagat ttattatcta taaaaattaa
    28621 actaagataa attataatta acaattatat atatgttatt tcaaaaatta aattaggaag
    28681 gatagttaaa taatgaaaat tttaactgta aataatttaa gtaaagtata tggtaaaaaa
    28741 ataattttca acgcattaaa tgacataaat tttagtatag aagatggaga atttgtagga
    28801 attatgggtc catctggtag tggaaaaact actcttttaa atatgatttc tactattgac
    28861 aagccaacta caggaactat ggaattaaag ggcaagaatc ctttattgtt aagaggtgag
    28921 gaacttgcat tatttagaag aagagagtta ggttttgtat ttcaggattt taatttattg
    28981 gatacattaa ctataggaga aaatatagta ttgccattga cattagataa ggtcagtgta
    29041 aaagagcaag atgagagatt gaatgaagta tctacaatat taggtataaa agatttatta
    29101 ggaaaaagaa cttttgaagt atcaggtggt caagctcaga ggactgctat tgctagagca
    29161 ttgattaaca atccatcaat acttttagca gatgaaccaa caggtaattt agattcaaag
    29221 tcatcaaagg ttgtaatgga gctatttcaa aagataaata aagaaaataa agttactact
    29281 atgatggtaa ctcatgaccc attagcagcg agctactgta gtagaatctt attcataaaa
    29341 gatgggtcta tatataatga aatatataag ggtagtagta gagagcagtt ttatcaagag
    29401 ataatggatg tacttacatt attgggaggc gataactaat gaatataaaa cagtttgcta
    29461 ttaacaatat ttcaagaaat attaaagcgt atttaggata cttagcaagt attgttatat
    29521 catcttcact gctattttct tttattatgt ttacaagtca tccagattta gatgtatctc
    29581 aatttcctga ttatttaaaa gaaggtctca agatgagtaa gataattgca tatctattct
    29641 tattcttctt tgtgttttat tcagttagtg tgtttcttaa aagtagatat aaagaatttg
    29701 gaatacttta tattacaggt atatcaaagc gccaagtaat gaaattaatc tttatagaaa
    29761 atatgataat aaatatagta tcttctgtaa ttggaataat aataggctta atctttgcaa
    29821 agatattttt agtggttatg tctacttttt tagaattatc accattaaaa ttctatatac
    29881 catttaatgc gatattgtct actttaatct attttatgat tttagctgta ttaacatcaa
    29941 tatttacttc ttttatagtt aaagaaaatc aggtgttgaa gttacttaaa ggtacaaaaa
    30001 ctccaaaacc agagcctaaa acatcactaa tgcttgctat attaagtatt tgtttgttta
    30061 taatagcgta ttataatgct attacctcaa ccgaccaata tacaacatat ctgcgcttag
    30121 ttccagttac atcccttact atagtagcaa cttacttgtt cttttctcaa tttagtgtat
    30181 tttttatgaa gaagctaaaa ttaaacaaga gattttatag aaaaaataca aatatgcttt
    30241 ggatttcgaa cttgatttat aaggtaaagg ataatgctag aatatttttc ttgataacta
    30301 taacttctgc agtggcattt actgctatag gtacagttta ttccttttgg aaagatgtag
    30361 agcgtcaaat taatttaata tatcctaaca caatatatta ttcaacaatg acattgcata
    30421 atgaccctaa aaagcctgat agcaaagaaa aagacaagga aagaatgatg tttatagaaa
    30481 ataatctaaa aaaagagaat gtagactata caaggattaa tggtgaattt aaaactgtat
    30541 ttcccaagaa aagtgatttt aatgtcagaa ttatgaaaga atctaagtac ttagaaatta
    30601 cagaaactat aggggttaag cctataagtt ttgaagataa tgaatgtata tcattattat
    30661 catcaagttt accaggaaat aagaacgtca aagaaaatat tattgtaggg aatagaggtt
    30721 taaaggtggc aaaacaagtg gaagaatgtg ttatgccagc gtattacaaa aatatgtatg
    30781 tggtaaagga taatttttat gatagtatag aatcaaaatt tatagtggat agatttactg
    30841 catttgaagt agaggattca agtaaaacta tagagatatg cagagaattt gaaaataaat
    30901 ttaataatga gtcagggatg caaccatatt tgtttttctc taaagaatta atgataggaa
    30961 ctgggaaatt aatgtattct acatttatat ttttagcaat atttataggt ttaattttct
    31021 ttgttactac aagtagtttt ttatataata aattttatat ggattgccaa gttgataaga
    31081 aaaagtatga acagttaaat aaattgggta tgacatataa tgagattaaa aaagcttcaa
    31141 caattgagat tggaatagta tttttgtttc cttatgtagt ggctgttata cattcaatat
    31201 ttgcacttac tgcactgaaa aattcttttg atatagaagt agcatcatca gctgttttgg
    31261 taatgggaag cttgttcttg gttcaaatag tttatttttt aattgtaaga aataattatt
    31321 taaaagagat aaggttaaat ttagtcaatt tttagttact attattaaat gataataaaa
    31381 agggtttaga attaattaat attactggaa ttatagatgt ttattttttc agtaatattt
    31441 tttattgtat taactattaa aattttgtac aaatataaaa tataatatgg taaatgtcaa
    31501 aattataaaa aaat
//
LOCUS       DAJMZY010000039        30930 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.039, whole genome shotgun sequence.
ACCESSION   DAJMZY010000039 DAJMZY010000000
VERSION     DAJMZY010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 30930)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30930)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30930
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.039"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            complement(388..2307)
                     /gene="cooS"
                     /locus_tag="OE968_001761"
     CDS             complement(388..2307)
                     /gene="cooS"
                     /locus_tag="OE968_001761"
                     /EC_number="1.2.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic carbon-monoxide dehydrogenase
                     catalytic subunit"
                     /protein_id="HCP7219042.1"
                     /translation="MDEKMLTIDLNSQKMIAKAREEGVETMYDRKEGFKAQCGFGLQG
                     VCCRICGMGPCRISPKTPRGLCGADEHTIVGRNFARMVAGGTAAHSDHARDIAHTLAL
                     ADPNGNYKIRDEAKLITLAKEWDVETEGRDIYDVAHEVAEIALMEFGKPFGTLRFIKN
                     APEPRQKIWKEYAIEPRAIDREIATIMHSTHIGCTGDIDSLIHMSLRTSMADGWGGSM
                     IGTRLSDILFGTPVPRRTEANLAVLEENKVNIILHGHEPALSEMIVLASEEPDLVALA
                     KEVGADGINLAGMCCTGNEITMRHGVKIAGDFHQQELAIITGAVEAVIVDVQCIFPAL
                     ARVADCYHTKFVTTSPKAKITGSTYIEFREEQALDDAKAIVKEAILNFKNRDKSKVLI
                     PELKSGATVGYSVEAVVNQLDRVVNSHIDPAGTVKPLTDCLKAGVLRGAAGVVGCNNA
                     KGVSNEAHVTIMKELIKNDIIVVTTGCGASAAAKFGLMESDAAEKYAGKGLATVCKLV
                     GIPPVLHMGSCVDISRILDLVGAAANYLDMDMCDLPVVGIAPEWMSEKAVAIGCYVVA
                     SGIDTYLGIMPPIAGSSRAVDILTSELKDKVGATFTVNTNPKELAATIIEDIEKKRVH
                     FEALVEEKMAEKAEA"
     gene            complement(2914..3825)
                     /locus_tag="OE968_001762"
     CDS             complement(2914..3825)
                     /locus_tag="OE968_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional enoyl-CoA hydratase/phosphate
                     acetyltransferase"
                     /protein_id="HCP7219043.1"
                     /translation="MIKKLDDILEQLKGGEKIVLSVAAAHDKEVLMAIKDAVERNIIT
                     PILVGNEGKIREISKEIGFDLSGIKIVDKDDIKECAEIAVKLVSSKEADFVMKGLLDT
                     SVILKEVLNKDYGLRTDSLLSHVMVYELEKYHKLLITTDGGMNIAPDYEQKAKILKNS
                     IKAAKALGMETVKVACLAAKEKVNPKMQATVDADMLAKACKEGEFGENVIVEGPLAFD
                     LAVSKEASEIKGFKSEVSGDVDIILVPTIEVGNGIGKAFTYMADSKSAGIIMGAKAPI
                     VLVSRADSHESKLYSIAYGAIVAKNMK"
     gene            complement(3941..4519)
                     /locus_tag="OE968_001763"
     CDS             complement(3941..4519)
                     /locus_tag="OE968_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HCP7219044.1"
                     /translation="MNINEFLTHINQRKPVSSKSEIHEFMVKLSNEAMKITSKLNSSY
                     HEPEEVRSLFSELIGKKVDESFFMFPPFYTDCGKNITIGKNVFINSSCHFQDQGGIEI
                     GDNTQIGHNVVLATLNHGIAPEKRGTTYPSPITIGKNVWIGANVTVVPGVTIGDNAII
                     AAGAVVTKNVAENTIVGGVPAKLLRAIDEIPE"
     gene            4745..5668
                     /locus_tag="OE968_001764"
     CDS             4745..5668
                     /locus_tag="OE968_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCP7219045.1"
                     /translation="MEIRVLRYFLAIAREESISGAATFLHITQPTLSRQIMELEEELG
                     VKLLVRGNRKITLTNEGRLLHKRAEEIISLVDKVELEFDNPNEIISGDIYIGSGETEA
                     MRLIARTAHHFHQKYPNVRYHLFSGNADDVTEKLDKGLLDFGILIEPANIQKYDYAQI
                     PATDVWGLLMRKDSALASQSTINPKDLCNIPLIISRQTLVDKAISKWLQGSNEKLNII
                     ATYNLVYNASLLVEEGLGYALCLDRLVNTTENSNLCFRPLSPPLEAKLNIIWKKHQIF
                     SKAAEKFLLQIQKDFSSIMLDTSKLDTPKEK"
     gene            complement(5840..6982)
                     /locus_tag="OE968_001765"
     CDS             complement(5840..6982)
                     /locus_tag="OE968_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HCP7219046.1"
                     /translation="MDFKIEKYLLKKAEELAFITIKHGGEFKLKSYEVPKGGLDVPIK
                     NEVLVKGIKEKTAQDKLNSMSIADAMIYIIGIDSKFKNNAEYEKFLNALSKDIDLDLK
                     SYMGYMSRKYFEIGEHTDSLIYIKAFITMYPDDLDAMYNYAIVCQEIAKQYQKDMDDK
                     AMNAFLLEAMAKLEKVIDVDENFALGYYHLGYHYYNQGQYLKTKLTWEEALRLGLDAD
                     LVAEVQENLGKMDFKVQYEEGYTLVFQGKFKEGLEKLLPLEEEHMDWWNLLFMIALGY
                     KGMGEIEQAKMYLEKILIIKPNQVDTIVELGLCEAYKNNLDKAIEYFEQAAKIKEDPE
                     ILCNLGMAYLNNGDIDDATYYIERAYELNPQDEITIACLRELGINK"
     gene            complement(7000..8754)
                     /locus_tag="OE968_001766"
     CDS             complement(7000..8754)
                     /locus_tag="OE968_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="B12-binding domain-containing radical SAM
                     protein"
                     /protein_id="HCP7219047.1"
                     /translation="MKILLTTLNSKFIHTNLAIRYLKEFVRDLIEVNMKEYTINNDLD
                     YILKDIYKNEYDIILFSTYIWNVGDIVKLCDNLKKIRPNTKIALGGPEVSYDSYEAMK
                     KYDFVDYILYGEGELIFRDLVLHLQGKMEINDVNGLVYRQGNEIIVNKPMELLQDLDE
                     IPSPYENLNPKEYENRIVYYESSRGCPFNCQYCLSSTIPGLRYFSLDRIKSDLKALID
                     ARVSQIKFIDRTFNANRKVAMEIMDFLMKNDNGYTTYHFEVTAYLIDDKMLEFLADCK
                     EGLFQFEIGVQSTNEKTLDAVGRRDDFKKLSHVVQTVASYRNIHQHLDLIAGLPYEDY
                     KSFENSFNDVFNLGIEHLQLGFLKMIKGTGMRKVADEHGFKYKDYAPYEFLYNNYISY
                     EETLKLKDIEDILERYYNSKNFVLSMRYIIGRFYKKSPFKFFEVFAKYFDENGYFDLA
                     QGKNQLYKILMDFYNEKINIDNDVFNDILKYDYISLGKTSNIPQFFNKLDVDDFKNRC
                     HVFLQDNDNLSTYLPSFVDKPAKHIIKYVHFEPFRFNVVDLKNDINTEIREVENVVLF
                     EYDDKKIFEKSKTHKVEI"
     gene            8890..9096
                     /locus_tag="OE968_001767"
     CDS             8890..9096
                     /locus_tag="OE968_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219048.1"
                     /translation="MELIEKVSINSLSKRDLLLIIKSLEYTNENTQISDFIDLRNNIV
                     KELCFLTDTKEKDFLDYLEKNSTL"
     gene            complement(9101..10024)
                     /locus_tag="OE968_001768"
     CDS             complement(9101..10024)
                     /locus_tag="OE968_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219049.1"
                     /translation="MNDELLKKVYTSSFSSASRALKDLTIINTKSLIDDKTQRCVYID
                     ENRLRDELIYYRFYGEKIGNINFLNILLPLILSNTNIQKSEDEVIKLIKKYVIYFKKE
                     ELLFDYLLGSVVYNSIMHNLINNSKIEYVELLQSIKDKIIGFSIELDKSDVVKFQMAR
                     IKAIQLIDKYIDLKSEDYDEESILLNVLNVLYDVYMEDRTVENEGINSIKKSILSILG
                     EDSKLNEDNIDFIFSMSEYVVKLRKYKIGVKAYNKSIDPRSLIRLEEGNTIVDPIFNQ
                     ITVMSKTFNDNILSIKINSKSGIYILKFKKV"
     gene            complement(10278..11978)
                     /locus_tag="OE968_001769"
     CDS             complement(10278..11978)
                     /locus_tag="OE968_001769"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HCP7219050.1"
                     /translation="MQDFKVAISNCLKEKIEDLSKEEIEALIEVPPNKDMGDYAFPCF
                     KLAKVFRKAPNMIASELAESIEPSGEITKVIQLGGYVNFFVNKSQLAETVIKKVLDEK
                     ENYGHSDFGKDKTVIVEYSSPNIAKPFHIGHIRTTVIGNALYKIYDSQGYKTIRINHL
                     GDYGTQFGKLIVAFKKWGEKEVVESNPIPELLKLYVRFHDEAEQHPEMEDEARAWFNK
                     LENGDEEAQELWQWFRNESLKEFNRVYKLLDIEFDSLAGESFYSDKMNRVIELLEEKN
                     LLKESKGARIVDLEEYKMPPALITKNDGSTLYMTRDLAAAIYRKETYDFDKCIYVVGS
                     QQNLHFQQWFKVIELMGYDWAKDLIHVGFGMVALEEGTMSTRKGRVVFLEDALNQAID
                     KTKEIILAKNPNAKNVDEISKQVGVGAVVFQELSNSRIKDYTFSWERTLSFDGETGPY
                     VQYTHARCCAVLRKAEVEVTSDIDYSLLADEDSAEVLRVIESFNKNILLALKKNEPHI
                     VTRFMLDLAQAFNKFYHDNPILVENLEIRKARLALVLATKQTLENSLKLLGMHAPERM
                     "
     gene            complement(12388..12801)
                     /locus_tag="OE968_001770"
     CDS             complement(12388..12801)
                     /locus_tag="OE968_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HCP7219051.1"
                     /translation="MILVSACLIGINCKYSGDNNDNEKVKEYLKGKEFTLVCPEQLGG
                     LSTPRPPAEIVDGKVITKDNKDVTENFVRGANETLKIANLYVCSEAILKEGSPSCGCN
                     LIYDGSFSGKKIPGKGITARLLEEEGIKVKSEKDL"
     gene            complement(12867..15245)
                     /locus_tag="OE968_001771"
     CDS             complement(12867..15245)
                     /locus_tag="OE968_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HCP7219052.1"
                     /translation="MNEKSLRVLEYNKIIDLLKKKASSSLGLKYIENLVPNTDFVEVK
                     SMLEETSEAQSIIIKRGSVGLEGIHDIEDKVKRAYIGASLDPGSLIMIADTLRVARRL
                     RNSLSSSDEEDFNYPIIQSLSNSLYVYKDIEDQIYNAIISEVEISDNASSTLRDIRRR
                     IAQKNQSIRSKLNSIISSTTYQKYLQDAIISLRGDRFVVPVKSEYRSQVAGIVHDQSS
                     SGATLFIEPMTIVEMNNELRQLKLGEQEEIERILSELSAMVGEVSEDLISNQEILGRL
                     DFAFSKGKLSIQMRGIEPTLNEDKYLNIKNGRHPLLDKKKVVANTIYLGRDFHTLVIT
                     GPNTGGKTVTIKTVGLFALMTQSGLHIPADYGSSMCVYDNVFADIGDEQSIEQSLSTF
                     SSHMTNIVSILQNVTADSLVIFDELGAGTDPVEGAALAIAVLEDINSVGAKCIATTHY
                     SELKNYALTKPGVENAAVEFDIETLSPTYKLLIGVPGKSNAFEISRKLGLSDYVISRA
                     KEYINTENIALEDVLQNVEKNRIKAVEDREEAERLKEEIEKLKVEYDEKLEKLVSQRD
                     KMIEKAKSEAFSIIRQAKEEVDIIIKELRSLEQERASKEKNRKIEELRKELTSSMGSL
                     QPTVKSMIVPKVSNKEIKDLKPGEEVKVITLNQNGSVVSVDKKRKEAVVQIGIMKMTL
                     PFKSLQKTRKDVSTNVTKSTRNIIRSKSGSVKNEVDLRGLNLEEAIMEVEKYLDDAYV
                     AGLESVTVIHGIGTGVLKAGLQDILRRNRHVKSQRGGQYGEGGAGVTIVKLK"
     gene            15564..17015
                     /locus_tag="OE968_001772"
     CDS             15564..17015
                     /locus_tag="OE968_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-histidine dipeptidase"
                     /protein_id="HCP7219053.1"
                     /translation="MGNVLEGLKPESVFKNFEKISQIPRGSGNEKGISDFLLSFGKNL
                     GLETIQDESLNIIIRKPATKGYENCPGVVLQGHMDMVCEKEKNVEHDFLKDPIKLRID
                     GDMIYATGTTLGADNGIAVAMGMAILEDNTLEHPALEVLVTVNEEDGMNGADALDPSL
                     IKGQYILNMDSEEEGYLLVSCAGGKTCVVSLPVEYKEVKGDKQGLLVEVTGLLGGHSG
                     MEIVLQRANANKAIARVLSVLNVDYELASVDGGTKHNAIPREAKCVIAVNKADVESAK
                     KQINDILTAFKHEFTTSDPGMTYSVAETSVDKVLTKDCKEKVVQMSCLTPHGVQSVSL
                     DIEGLVESSTNFAIIETKESTIEFLTSVRSSVMSIRDEIADRIRLLAQALGANYDLIA
                     QYPAWEFKKGSKLEKICSETYEKLTGKVPTVMALHAGLECGLLLDKLPHAEAISIGPD
                     MFDVHTPNEHVSIPSVANVWDYVIEILKSMNQY"
     gene            complement(17219..19732)
                     /locus_tag="OE968_001773"
     CDS             complement(17219..19732)
                     /locus_tag="OE968_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HCP7219054.1"
                     /translation="MEDCVVNLKKLLLLIIVITSIFTSCIFSFGINAIGNDNRTIRVA
                     YPIQKGLTEIDEQGNYFGYTYEYLLEIAQYTGWNYEFVQVPGEINESITKLMKMLENG
                     EIDIMGGMLYNEPMQKIYNYAGNNYGVANTVLQALYENTDIDNIMSSQDVKKIRIAVI
                     ENSDTRLKELDEYCKMNLMSPELVYCKTNDEQLEALKSGKADVLLNVSMNPIEGVRTV
                     AKFSSKPFYFITPKGSTNLTQKLNSAINNIEQKDPYFSTTLYEKYFTPENNQMFLSDE
                     ETNYIKETEKLKVGVLLNKPPFQNIDKDTGELRGISIDLLNHICDKTGLEFELVPVKS
                     QEDLENMTKKREIDIVAGMIYDYEYSREHNIAMSRPFLSTQYTMMINNKLNENSLDGK
                     RVALAKGINYYGQFEENIVWYDNLEECIEAVNKGYADYTYGEGYSMQYYMNQPKYKNV
                     RLVPQTYKAKSICFGIIKKDKQELLNIFNKAIISISSEKMQSIVYQNTTYRQDFSLLY
                     IMQQNPIETIFIVASLLICIIGFMAFGLHTRTSMNEKISLELKKHTQLYEMTSEYFFE
                     YDYKQDKLIISMPEKGIETYYGLDKNDKESENGNIENERDKIRKEYNKKFFDVIKSQE
                     NGTTEMYSIMLDDTFHWIRVTSKIIYNDRKIPMYVIGKICNIDSEKEEKNRLLDKAQR
                     DSLTNIYNAAYIRKLTSQNLLNLSTEKNGALLIIDIDYFKSINDTYGHLLGDKVLIDV
                     AKALDESFAKNDIVGRLGGDEFSVYINDIINKEELINKCNDVYNHIHLIKLPNGESLS
                     ISMGVVIAKPGQEYDELYQIADNALYDSKRQGRNRFKIV"
     gene            complement(19955..20776)
                     /locus_tag="OE968_001774"
     CDS             complement(19955..20776)
                     /locus_tag="OE968_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HCP7219055.1"
                     /translation="MIDINLEKCVGCGMCESDCLVNAIKVKDDKAKVKNILCINCGHC
                     MAICPTDAIEMQGFDKNEVIEYNRESFELEPEKLLNFIKFRRSIRQYKDIEVEEEKIK
                     NIVEAGRYTPTGGNRQPIRYILVKEKLKEVKELAIQGLYNLALDTDDNDPVRSIYKNT
                     FKKMYKRYKENGNDSLFYDAPLLMVVVGDMSLGGSAYVDGGLAASNMELMAYSQGLGI
                     CYNGFFVMASNVEPKIKELLGMSENEAVITSFILGYPDVKYKRTVNRNTAKFEVR"
     gene            complement(21294..21770)
                     /locus_tag="OE968_001775"
     CDS             complement(21294..21770)
                     /locus_tag="OE968_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HCP7219056.1"
                     /translation="MKLTTICYIEKDDKTLMLYRNKKKDDIHEGKYVGVGGKFEQGET
                     PEECVIREVKEETGLTLKSLSYKGLITFPKFKDEEDWYMFLYFSDEFEGELSEKDLND
                     CKEGNLIWVDNDKIFDLNMWEGDRLFLNWAKTGNIFSAKIVYDNGKLKDYNVSFLD"
     gene            complement(21805..22383)
                     /locus_tag="OE968_001776"
     CDS             complement(21805..22383)
                     /locus_tag="OE968_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HCP7219057.1"
                     /translation="MREEALEILFKYLETDRMRKHCYAVEAVMRELAKRLEPEKEEEW
                     AVAGLLHDLDSDIVGRKPGEICEGHATTTVELLKKENFGNEEMYRAILGHHDGMGVTR
                     TSLMEKAIYAADPITGFITAIALVYPDKKLTSVKTKSVIKRMKETRFASNVNRDAMRS
                     IEDIGIPFDEFAELSLNAMKNISDVLESAENN"
     gene            complement(22487..25087)
                     /locus_tag="OE968_001777"
     CDS             complement(22487..25087)
                     /locus_tag="OE968_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HCP7219058.1"
                     /translation="MKKIELLAPVGSFDSLKAAVQNGANAVYLGGKDFSARASANNFD
                     RNELIEAVKYSHIRGVQVFVTVNTLIKQYEIEDFVEYVKFLYDIDIDALIVQDIGMAR
                     LIKKLLPDFELHASTQMVAHSLEDVKYLQSVGFDRVVLARELNVDEIKWICENTTVDI
                     EVFVHGALCVCYSGQCLMSSMIGNRSGNRGRCAQPCRQKYELIDINTGEVVKSNGDYL
                     LSPRDLSTIEDLDKIIEAGVLSLKIEGRMKKPEYVATVVSGYREAINEFVDKKKISIS
                     EEIINNLYTIFNRKFTKGYILGEVGKDIMNSNRPNNQGLYIGKVLDYNRKNKRLRVML
                     ENTLKKGDGINLGGGTIGRIIKDGEITTIAHKGDLIELDFVGEAKRNQLIYKTSDSEL
                     MDRVQATFQQDKEFIKTNIRAKVSIKLGKKPELFISDFCGNKSVVEGDKIVEKAIKVA
                     LSKEKIETQIQKLGNTPYKLKEIEIDLDEGVSMPISVLNQMRRDCIELLDEERIKIKD
                     RKFKKNRLKYQPNRVNKQKKLDTAPKIRVKVKNLEQLEAVLNYNVDLIYYEDINTLSK
                     ALQMVSSISIDSNISIDSSISMDLDTSSSLGTPKELMGSNTNNIDTLSNTSKIDTLNK
                     NHSNTAVTDKKLIYSAPRIVRNKEYKQFEILDNIKGINKVQIGNWGSMEYFKKKDLNI
                     DCYLNVFNSESINHFKEEGASTVCLSQELNLNEIKQTLKYTDVEIEAVIYGYAPMMVT
                     EYCPMGVVVRDCKKDKRVAKCKESSYALRDFTDASYRITQDIFCRSTIYNSKVTCMLD
                     NLYELEEIGIDVFRIDFTVEDSEMVKKVIEAHIEVLSNNYKLGKKATDLYKKLDEIGT
                     VAGHYYKGVE"
     gene            complement(25657..26340)
                     /locus_tag="OE968_001778"
     CDS             complement(25657..26340)
                     /locus_tag="OE968_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HCP7219059.1"
                     /translation="MTSKSQMSESFFLCSLLAITGGFLDIYTYVVRGKVFANAQTGNI
                     VLFGLNIAEGNVKESFYYLIPILAFMLGVFIAEKIRKYFTNNKTKIHWRQVIIIIEMI
                     TILIVSFIPRGRFNMFVNVAISFICSMQVESFRKVNGNSFATTMCTGNLRSATETLFH
                     YIHTKNIFMIKKSLQYYAVIIFFISGAILGTFFTKIFVEKSILICFFILAVVFGIMFI
                     NKDDSFNEN"
     gene            complement(26516..27106)
                     /gene="zapA"
                     /locus_tag="OE968_001779"
     CDS             complement(26516..27106)
                     /gene="zapA"
                     /locus_tag="OE968_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HCP7219060.1"
                     /translation="MNKVMVKIHGAEYPMVGDKSEKFMISIADFVDKEMDKITRQNPK
                     LSLSVAAILTALNISDLLFECSDENEKLIKANEELSKKVGASNEELQLEIKSLKLTIA
                     EKEAENREAETKMKELIEIIENKKQEIFELSNTTEGSRAELDAYKNKIEELSTQLEEA
                     NERATIAENLASEFQNKAYDLQLKCTGLNNDAKNVE"
     gene            complement(27131..29524)
                     /locus_tag="OE968_001780"
     CDS             complement(27131..29524)
                     /locus_tag="OE968_001780"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HCP7219061.1"
                     /translation="MLVSLKWLRDYVDIDMDVKEFADKMTMTGTKVETIDYYGEEIEN
                     ILVGKILEIKQHPNADKLVVTKVDIGDKVVQIVTGATNISEGDYIPVAVNGSKLPGGV
                     EIKQTDFRGELSDGMMCSAAELGIDEHYIEEYKRGGIYILDHEDSYELGKDIKDVLGL
                     KDALIDFELTSNRPDCKCMMGIAREAAATIGTKVKYPEIEVKESDEEIDFKVEIDNPD
                     LCRRYVARMVTDVKIEPSPYWMQRRLTEAGVRPISNIVDITNFVMLELGQPLHAFDIN
                     QVETGRIVVRNAKDGEKLVTLDDVERTLDKDMLVITNGEKSLGLAGVMGGANSEITSN
                     TKTVLFESANFKPENIRMTAKKVGIRSEASSRNEKDLDPNLAEIAANRAAQLVEMLGA
                     GKVLKGVVDVYPNKPEPKKLVVNPQRINHLLGVDVPMEQFVGILESLEFKCNLVANDK
                     LEIDVPSFRTDMEQEADVWEEIARIYGFENIPSVQLEGNTTAGIKTSKQKFMDALKDN
                     STAVGLNEILTYSFVSPKGVDKIRVPEGNAKRNFVKLLNPLGEETSVMRTTLIPNMLD
                     VLSTNVSHKIEEVSAFECGHIFIPQDSELPKEENRMCVGMYGKDVDFFALKGTIETIL
                     VNVGFKGYEIEPQDNNTTFHPGRCAKIVYNNKYVGTLGELHPDVIENYNLGQRVYVAE
                     IDIDFVFDNSDRTKNYVPLPKYPSTSRDIALIVKDDVFVKQIEDIIKENGQGLVESYK
                     LFDVYKGSQIEAGYKSIAYSITYRSKDKTLTDEDVAKVHDKILSELSEKLNANLRSN"
     gene            complement(29541..30560)
                     /gene="pheS"
                     /locus_tag="OE968_001781"
     CDS             complement(29541..30560)
                     /gene="pheS"
                     /locus_tag="OE968_001781"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HCP7219062.1"
                     /translation="MQEKLLALREAALAEIKEAQSIESVESLRVKYLGKKGEITAILK
                     EMGKLSAEERPVVGKVANEVRENIELSINSKKEEINAIEKERKLKEEVIDVTQPGKVL
                     KVGKKHPITQIIDEVTDIFIGMGFSIAEGPEVETVENNFDALNAPKDHPSRDMSDTFY
                     INDGVLLRTQTSPVQVRTMRSQELPIKVIAPGRCFRSDSPDATHSPMFHQIEGLVVGK
                     DVTMAEFKGTMDIFVEKLFGSDIKTKFRPHNFPFTEPSAEVDVTCFKCGGKGCPMCKY
                     EGWIEILGSGMVHPNVLRNCGIDPEVYSGFAFGVGVERLAMLKYEIDDIRLLFENDMR
                     FLNQF"
     misc_binding    complement(30610..30844)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
BASE COUNT         9578 a         5693 c         3428 g        12231 t
ORIGIN      
        1 ttcagcaaac atcctagaga gcattgaaga aaaagtcgtt ttacctactc cacctttacc
       61 tgttattgct atcttcataa tccctaccac cttttattac tatttgcttt ttagtagtta
      121 attttacagt taaatatttt ttatactcta tatttttata cactaaaaat aaactacagc
      181 tagtccttac aggaaccaat taaatttacc ctactagctt ttcaaagcag catgtatagt
      241 tttattattc tttaatattg tttatatttt atttattcag tatattcatt atattttgat
      301 gttctttact ttaatatttg actttattca actttattca accagaaact tcttataaaa
      361 acgtttattc tataacttca ctatttttta agcttcagcc ttttctgcca ttttttcttc
      421 aactaatgct tcaaagtgaa cacgtttttt ctctatatct tctattattg tagctgctaa
      481 ctcttttgga tttgtattta cagtaaatgt agctccaact ttatctttta attcactagt
      541 taatatatcc actgctcttg aagaaccagc tattggaggc attattccta aataagtgtc
      601 tataccagaa gctacaacat agcatcctat agcaactgct ttttctgaca tccactctgg
      661 agctatacct acaactggaa ggtcacacat atccatatct aagtaattag ctgctgctcc
      721 aactaaatct agtatacggc ttatatcaac acaagaaccc atatgtagta ctggtgggat
      781 tcctactaat ttacagacag ttgcaagacc tttacctgca tatttttcag ccgcatcaga
      841 ttccattaaa ccaaacttag ctgctgctga agctccacaa cctgtagtaa ctactattat
      901 gtcgtttttg attaattctt tcattattgt tacgtgagcc tcatttgaaa ctcctttagc
      961 attgttacat ccaactacac cagctgctcc tcttaatact ccagctttta aacagtctgt
     1021 taatggctta actgttcctg ctgggtctat atgagagttt acaactctgt ctaattgatt
     1081 tactactgct tctacactat acccaactgt tgcgcctgat tttaattcag gtataagtac
     1141 ttttgattta tctctatttt taaagtttaa aatagcttct ttaactattg ctttagcatc
     1201 atcaagtgct tgttcttctc taaattcaat ataagttgaa cctgttatct tagcttttgg
     1261 agaagttgtt acaaatttag tatggtaaca atctgcaact ctagctaatg cagggaatat
     1321 acattgaacg tcaactatta cagcttcaac tgctccagtt attattgcaa gttcttgttg
     1381 atggaagtct cctgctattt ttacaccatg tctcattgta atctcattac ctgtacaaca
     1441 catacctgct aagtttattc catcagcacc aacttcttta gctaaagcta ctaagtctgg
     1501 ctcttctgat gctaaaacta tcatttctga taatgctggc tcatgtccat gtaatattat
     1561 gttaacttta ttttcttcta atactgctaa attcgcctct gttcttcttg gcactggagt
     1621 tccaaataag atatcgctta gacgagtacc tatcatagaa ccaccccaac catcagccat
     1681 agaagttcta agactcatgt gtattaaact atctatatca ccagtacatc ctatatgagt
     1741 agagtgcatt attgttgcaa tttctctatc tatagctctt ggctctatag cgtattcttt
     1801 ccatattttt tgtcttggtt ctggtgcatt ttttataaat cttaatgtcc caaaaggttt
     1861 tccaaattcc attaatgcaa tttctgccac ttcatgtgct acatcataga tatctctacc
     1921 ttctgtctct acatcccatt ctttagctaa agtaattaac ttagcttcgt ctcttatttt
     1981 atagtttcca tttggatcag ctaatgctaa tgtatgtgct atatctctag catggtctga
     2041 atgggcagct gtcccaccag caaccattct tgcaaagttt ctacctacta tagtatgctc
     2101 atctgctcca cataaccccc ttggagtctt agggcttatt ctacatggtc ccattccaca
     2161 tattctacag caaacacctt gaagaccaaa accacattgt gccttaaagc cttcttttct
     2221 atcatacatt gtttctacgc cttcttctct agctttagct atcatcttct ggctgtttaa
     2281 atcaattgtt aacatttttt catccatatt cctatcccct ttttttgatt tttaaaatcc
     2341 cccaggtgac tgacttcatg tcataaaata ataaaataaa tgctttctaa gttgattata
     2401 tactaatttt cagtgctttg ctttagattt aaatattttt ttaacaaaat tagataatac
     2461 ataaaaattt tattttctac acttaattta agttgatttt atcgcttgtt tttggctatt
     2521 tgttaatatc taaacctact tttttgatac ttcagtttaa ttaaattatg ttttgatttt
     2581 tttaaatcaa atttgaaatt tttctagtca tttttatatt attgcagatt gtttgtgtat
     2641 ttattatctt tcactactgt ttggacttat tacagatttt tactccctaa acttaattag
     2701 taaaaatttc ttagaatagc attttttgga ctaatttttt tgaatttttt tatttttcct
     2761 actttaatat taattatagc ttcaaattga acatttgtat atattcattt gaagctataa
     2821 ttatttttta tataaaactt ttttaataca gcattaattt agacattttg actatttttt
     2881 ctactttaat tcatttattt caagcgattt atcctatttc atatttttag ctacaatagc
     2941 cccatatgca atagaatata atttagattc atgtgaatca gctcttgaca ctaaaactat
     3001 aggagctttt gcacccataa ttatacctgc tgatttagag tctgccatat atgtaaaggc
     3061 tttccctatt ccattaccaa cctctattgt tggaaccaat atgatatcta catctccaga
     3121 tacttcactt ttaaaccctt ttatctcact agcttctttt gaaacagcta aatcaaaagc
     3181 cagaggacct tctacaatta cattttcacc aaattctcct tctttacaag cttttgctaa
     3241 catatctgca tctacagttg cttgcatctt aggatttact ttctctttag ctgccaaaca
     3301 tgcaactttt acagtttcca ttcctaaagc ttttgcagct tttatagaat tttttaatat
     3361 ctttgccttt tgttcataat caggagctat attcatacct ccatctgtag ttataagtaa
     3421 tttatggtat ttttctaact catataccat aacatgactt aataaactat cagttctaag
     3481 accatagtct ttatttaaca cttcttttaa tatgacagat gtatctaata atcctttcat
     3541 tacaaagtca gcttctttac ttgatactaa tttaactgct atttctgcac actctttgat
     3601 atcatcctta tccactattt tgataccact taaatcaaat cctatttctt ttgatatttc
     3661 tcttattttg ccttcatttc caaccaatat aggagtaatt atatttcttt ctacagcatc
     3721 ctttattgcc attaaaactt ctttatcatg agctgctgct acagagagta caattttctc
     3781 tcctccctta agttgttcta aaatatcatc taattttttt atcaaaagta acccctccct
     3841 tatatatatt taactaaata ataccatatt tgctatacct tttctcaatt tattttttat
     3901 gttataaaga atttatataa ctaaaagaca gtttaatatt ttattctggg atttcatcaa
     3961 tagctcttaa aagctttgca ggaacaccac ctacaatagt attttctgca acattttttg
     4021 ttacaactgc tccagcagcg ataattgcat tatctccaat agtaactcct ggaactacag
     4081 ttacattagc accaatccat acattttttc ctattgtgat tggagaagga taagttgtac
     4141 cacgtttctc tggtgcaata ccatggttaa gtgtagccaa taccacatta tgcccaattt
     4201 gcgtattatc tccaatctca atccccccct ggtcttgaaa atggcaactg ctatttataa
     4261 aaacattttt tcctattgtg atgttttttc cacaatctgt ataaaatggt ggaaacataa
     4321 aaaatgattc atctaccttt tttccaatta actcagaaaa taaactacgg acttcttctg
     4381 gttcatgata agaagaattt aacttacttg tgattttcat tgcctcatta ctcaacttaa
     4441 ccataaattc atgtatttct gatttactag aaacaggttt tctttgattg atatgtgtta
     4501 aaaattcatt gatattcatt ttatacatcc tttcaatatg tgctttaatt tatttgtaca
     4561 ttctaaataa tattttaata aaaattaatt taatttattt ttattaaaat atcattgctt
     4621 cttttagtgt aatatacaat tatatctata tcaaatatct atattaaata cttaactata
     4681 cttaaaaagc atataaattg atataattat ataataaata agttaatatt gaggagggat
     4741 aattatggaa ataagagtat taagatattt tttagcaatt gcaagagaag aaagtatatc
     4801 tggtgcggca acctttttac atataacaca accaacactt tctagacaaa ttatggaact
     4861 tgaagaagag ttgggagtta aattattggt tcgaggaaat agaaaaatca ccttaacaaa
     4921 tgaaggtagg cttttacata aaagagcaga ggaaattata tcattagttg ataaggttga
     4981 attagaattt gacaatccca atgagattat tagtggtgat atatatatag gaagtggtga
     5041 aactgaagct atgcgactta tagctagaac tgcccatcat tttcatcaaa aataccccaa
     5101 tgtaagatat caccttttta gtgggaatgc tgatgatgtg actgaaaaat tagacaaggg
     5161 actgcttgat tttggtattt taattgaacc tgcaaatata cagaagtatg attatgcaca
     5221 aattcctgct actgatgtat ggggtttact aatgcgtaaa gatagtgccc ttgcatcaca
     5281 aagcacaata aatccaaaag atttatgcaa tatacctctt attatttcaa gacagacact
     5341 tgttgataaa gcaatttcta aatggcttca aggcagtaat gaaaaactaa acattattgc
     5401 aacatacaat ttagtttata acgcttctct tttggtagaa gaaggtctgg gctacgctct
     5461 gtgtttagat agactcgtca atactacaga aaacagtaat ctttgtttta gacctctatc
     5521 tcctccttta gaagctaaat taaatattat atggaaaaaa catcaaatat tttcaaaggc
     5581 agcagaaaaa tttttacttc aaatacaaaa agatttttct tctatcatgt tggatacatc
     5641 taagttggat acacctaaag aaaaataaat cataataaaa agtgagagtg tctcaaaatg
     5701 aactttgcac tgtataaggc actctttttt atacaaagta aaatatatgt tcatcatttc
     5761 agcactaaaa aagaggctta tctctatttt gagatagccc cacttaacca ataaaattaa
     5821 atacaactta acaatatcct tacttattta ttccaagttc tcttagacaa gcaatcgtaa
     5881 tttcatcttg tggatttaat tcataagctc tttctatata gtaagttgca tcatcaatat
     5941 caccattatt taaataagcc attcctaaat tgcaaagtat ttctgggtct tcctttatct
     6001 tagccgcttg ttcaaaatac tctattgctt tatctaaatt attcttataa gcctcacaaa
     6061 gccccaattc cactatagta tccacctgat taggctttat tatcaatatc ttctcaagat
     6121 acatcttagc ctgctctatt tcgcccatac ccttatatcc aagtgctatc ataaacagca
     6181 agttccacca atccatatgt tcttcttcta atggaagtaa cttctctaat ccttccttaa
     6241 acttaccttg gaatacaagt gtatatcctt cttcatattg aactttaaag tccatcttgc
     6301 ccagattctc ttgtacctca gctactaaat cagcatctaa ccctagcctt aacgcttctt
     6361 cccaagtcag cttagtcttt aaatattgac cttgattata ataatggtag cctaagtgat
     6421 aataacctaa tgcaaaattc tcatcaacat caattacctt ttcaagctta gccatggctt
     6481 caagtaagaa tgcattcatt gccttatcat ccatatcttt ttgatactgt ttagctatct
     6541 cttggcaaac aatcgcatag ttatacattg catctaaatc atctggatac attgttataa
     6601 atgcttttat atatattaaa gaatctgtat gttcaccaat ctcaaagtat tttctcgaca
     6661 tatatcccat atacgatttc aaatccaaat caatatcttt tgataaagca tttaaaaact
     6721 tctcatactc tgcattgttt ttaaacttac tatctattcc aattatatat atcattgcat
     6781 ctgctataga cattgaattt aacttatctt gagcagtctt ttcttttatc ccttttacta
     6841 atacctcatt ttttataggt acatctaatc caccttttgg cacttcatag ctttttaatt
     6901 taaactctcc accatgtttt atagttataa aagctaattc ttctgctttt tttagcaaat
     6961 atttttctat cttaaaatcc attttatcct cctaaatact taaatctcta ctttatgagt
     7021 tttagatttc tcaaatattt ttttatcatc atactcaaat aagactacat tttctacttc
     7081 tcttatttct gtatttatat cattttttaa atccacaaca ttaaatctaa atggctcaaa
     7141 atgaacatat tttattatat gtttagctgg tttatcaaca aaactaggta aatatgttga
     7201 taagttatca ttatcttgta aaaatacatg gcatctattc ttaaaatcat ccacatctag
     7261 cttattaaaa aactgtggta tatttgatgt tttacccagt gatatatagt catattttaa
     7321 tatatcgttg aatacatcat tatctatgtt gattttttca ttatagaaat ccatcaatat
     7381 tttatataac tgattctttc cttgtgccaa atcaaagtag ccattttcat caaaatactt
     7441 ggcaaaaacc tcaaagaatt taaaagggct ttttttataa aatctgccta taatatatct
     7501 catagataac acaaagtttt tagaattgta gtatctctcc agtatatctt ctatatcctt
     7561 tagcttcaaa gtttcttcat agcttatata attattgtat aaaaactcat atggagcata
     7621 atccttatat ttaaaaccat gctcatctgc aacttttctc atacctgtcc ctttaatcat
     7681 ctttaaaaag cctaattgca gatgctctat acctagatta aatacatcat taaaagaatt
     7741 ttcaaagctc ttataatctt cataaggcag tcctgcaatt aagtctaagt gttgatgtat
     7801 atttctataa gatgctacag tttgtacaac atgagacaac tttttaaaat catcccttct
     7861 acctactgca tcaagtgttt tttcattcgt tgactgaacc cctatttcaa attgaaaaag
     7921 accttcttta caatcagcca aaaactcaag catcttatca tctatcaaat acgctgtaac
     7981 ttcaaaatga taagttgtat atccattatc atttttcata agaaaatcca tgatttccat
     8041 agccactttt ctatttgcat tgaatgtcct atctataaac tttatttgtg atactcttgc
     8101 atctattaaa gcttttaaat cactctttat cctgtctaaa ctaaaatacc ttagacctgg
     8161 aatagtagat gataaacagt attggcagtt aaaagggcaa cctcttgatg attcataata
     8221 cactattcta ttttcatatt cttttggatt caagttttca taaggactag gaatctcatc
     8281 caaatcttga agtaattcca taggcttatt cactattatc tcattgcctt gtctatatac
     8341 aagtccattt acatcattta tttccatctt tccttgcaag tgaagtacta aatctctaaa
     8401 aattaattct ccctctccat aaagtatata atccacaaaa tcatactttt tcattgcctc
     8461 ataactatca taactcactt ccggtccgcc caaagctatt ttagtattag gtctaatttt
     8521 ttttagatta tcacaaagtt taactatatc tcccacattc cagatatatg ttgagaataa
     8581 tattatatca tattcatttt tatatatatc ctttaaaata tagtccaaat cgttgtttat
     8641 cgtgtattct ttcatattaa cttctatcaa atctcttaca aattctttta gatatcttat
     8701 agccaaattt gtatgaataa acttggaatt taatgttgtt aataaaattt tcaaatattt
     8761 ctcacctctt tttaagatta tactgtcttt ttgtacccct tataggttaa aatagtatat
     8821 gtaaagtcta aataatatct atataattaa tttattaatt tcaagtaatg tgaggaaagg
     8881 aagtttttta tggaattaat tgaaaaagta tctatcaact ctttatcaaa aagagattta
     8941 ctacttatta taaagtctct tgaatacact aatgaaaata ctcaaattag tgatttcatt
     9001 gaccttagga ataatatagt aaaggaatta tgttttttaa ctgacactaa ggaaaaagat
     9061 tttttagatt atctagaaaa aaatagcaca ctctaataac ctaaaccttt ttaaacttta
     9121 atatataaat acctgattta gaatttattt ttatgcttaa tatattatca ttaaaggttt
     9181 tcgacataac tgttatttga ttaaatatag ggtctactat agtattacct tcttcaagtc
     9241 ttataagact tcttgggtct atgcttttat tatatgcctt aactccaatt ttatattttc
     9301 tcaatttaac aacatattcg gacatagaaa aaataaaatc tatattatct tcatttaatt
     9361 tactatcttc acccaaaatg gataatatag atttttttat gctattaatt ccttcatttt
     9421 ctacagttct atcttccata tatacatcat atagaacatt taaaacattt aataaaatac
     9481 tttcttcatc ataatcttca gatttcaaat caatgtactt atcaattaat tgtattgctt
     9541 taatccttgc catctgaaac tttacaacat ctgatttgtc taattctata gaaaatccta
     9601 ttatcttgtc tttaatactc tgtagtaatt cgacatactc tattttacta ttatttataa
     9661 gattgtgcat aatggaatta tacaccacag aacctaataa ataatcaaat aaaagttctt
     9721 cttttttaaa ataaataaca tactttttta ttagtttaat aacctcatct tcactttttt
     9781 gaatattagt atttgataaa attagtggta ataaaatatt taaaaaattg atatttccta
     9841 ttttttctcc ataaaatcta tagtaaataa gttcatctct cagtctattt tcgtctatat
     9901 acacacatct ttgcgtttta tcatctatta aggattttgt atttattata gttaaatctt
     9961 taagagccct acttgcacta ctaaaagaag atgtgtagac tttttttagt aattcgtcat
    10021 tcataaatat atcctttctg aaaaattgaa tgtaaataaa ttgttattaa aaaaaaagag
    10081 acagcccgtt taagaagctg tcatatatag ggggatagta gtgtacaaaa atcattgtaa
    10141 tctactatct atatattatt atacgatact acttttttat atgtaaagca tcagttttcg
    10201 acatccctat attttacagt tatacaaatt gcgtactaag ttcaatttta ttctttttat
    10261 ttcaacattt tatcatgcta cattctttca ggagcgtgca ttcccaacaa tttcagagaa
    10321 ttttctaaag tttgttttgt tgctaaaact aatgcaagtc ttgcttttct tatttccaaa
    10381 ttttctacta aaattggatt gtcatgataa aatttattaa acgcttgagc taaatctagc
    10441 ataaatctag tcactatatg tggctcattt ttctttagag caagtaaaat attcttattg
    10501 aatgattcta taactctaag aacttctgca ctatcttcat cagctaatag actataatct
    10561 atatcagaag tcacttctac ttctgctttt cttaaaactg cacagcatct agcatgtgta
    10621 tactgaacat atggtccagt ctcaccatca aaactaagcg ttctttccca agagaaggta
    10681 tagtctttaa ttctactatt agataactct tggaatacta ctgccccaac acctacttgc
    10741 ttagatattt catccacatt tttagcattt gggtttttag ctagtataat ttccttagtt
    10801 ttatctatag cttgatttaa agcatcttct aaaaatacta ctcttccttt tctagtcgac
    10861 atagtacctt cttcaagtgc aaccatacca aatccaacat gaattaaatc ttttgcccaa
    10921 tcatatccca taagctcaat taccttaaac cattgttgga aatgtaagtt ttgttgagaa
    10981 ccaactacat atatacactt gtcaaaatca taagtttctt ttctatatat tgcagcagct
    11041 aaatctcttg tcatatataa cgttgaacca tcattcttag taataagtgc tggtggcatt
    11101 ttatactctt ctaaatcaac aattcttgct cctttagact cttttaaaag atttttctct
    11161 tctaatagtt cgataactct gttcatttta tcagaataaa aactctctcc tgctaaagaa
    11221 tcaaattcta tatctaaaag tttataaact ctgttaaact cttttaaact ctcatttcta
    11281 aaccattgcc ataattcttg tgcttcttcg tcaccatttt ctaatttatt aaaccatgct
    11341 cttgcttcat cttccatttc tgggtgttgt tcagcttcat catggaatct tacgtataat
    11401 tttagtaatt ctggaattgg attagactct actacttctt tttctcccca ctttttaaag
    11461 gccactatta acttaccaaa ctgagttcca tagtcaccta aatgatttat tcttatagtc
    11521 ttgtatcctt gcgaatcata tatcttatat aaagcattac ctataactgt agttcttatg
    11581 tgccctatat ggaaaggttt tgctatattt ggagaagaat attcaactat tacagtttta
    11641 tcttttccaa aatcactatg tccgtaattt tctttttcat ctaaaacttt tttaattaca
    11701 gtttctgcta attgagattt atttacaaag aaatttacat atccgcctaa ttgtattact
    11761 tttgttatct ctccacttgg ttctatactt tccgccaatt cacttgctat catgtttgga
    11821 gcttttctaa acactttggc taatttaaag catggaaaag catagtcccc catatcctta
    11881 tttggtggaa cttctataag tgcctctatc tcttctttcg ataaatcttc tattttttct
    11941 ttaaggcaat ttgatattgc caccttaaaa tcttgcattc tgttgctcct ctctacattg
    12001 ttcctggttt atattgtgct tatctcttta tgttaaatca aatttcgtgt tttttcaagt
    12061 atttcattac agtgtaaaac actttagtaa ttatgttttc tgtatatatt aaaaatacta
    12121 taatttcagt ttttaatcac actattattg attttttata agactttttt ctattttatt
    12181 gtttcttgta ctatccagtt gactttatat acttttttta atcttttatc tgttttcata
    12241 catcaatgtc agctttatat acattttttt aatcttttat ctattttcat acatcaatgt
    12301 cagctttata tacttttttt acttttttat ctatttttat acatcaatat tagctttata
    12361 tacttttttt actcttttat ctattttcta taaatctttt tcactcttaa cttttattcc
    12421 ttcttcttct aatagccttg ctgttatacc tttccctggt atctttttac ctgaaaaact
    12481 accatcatat attagattac atccacaaga ggggctaccc tcttttagta ttgcttcgct
    12541 acatacatat aaatttgcta tttttagagt ttcattagcc cctcttacaa agttttctgt
    12601 tacatcctta ttatctttag taattacttt tccatcaact atctcagcag gtggtcttgg
    12661 tgtagataga ccacctaact gctctgggca tacaagtgta aattctttgc cttttaaata
    12721 ttccttgact ttttcattat cattattatc gccactatat ttacaattta ttcctattaa
    12781 acatgcagat accaatatca taaaaatgtg ctcctataca aattatatat attctcatac
    12841 aaattactaa tgtattctta tacaaattat tttaatttaa caattgttac tcctgctcca
    12901 ccttctccat attgaccacc tctttgtgat tttacatgtc tatttcttct taaaatgtct
    12961 tgtagccctg cttttaatac tcctgtacct attccatgta ttactgttac agactctaaa
    13021 cctgccacat atgcatcatc aagatacttt tctacttcca ttatagcttc ttctaggttt
    13081 aaccctctaa ggtcaacttc attttttaca ctaccagatt ttgaccttat aatgtttctc
    13141 gttgatttag ttacatttgt tgaaacatct ttgcgtgttt tttgtaaaga tttaaaaggt
    13201 agagtcatct tcattatacc aatttgcact actgcttctt ttctcttttt atctactgaa
    13261 actacactac cattttgatt taaagttatt accttaactt cttcacctgg ctttaagtct
    13321 tttatctcct tatttgatac ctttggaact atcatacttt ttactgttgg ctgaagactt
    13381 cccatagagc tagtcaattc ttttctaagt tcttctatct tacgattctt ttcttttgaa
    13441 gctctttctt gttcaagact tctaagttct tttattataa tatctacttc ttctttagct
    13501 tgtcttataa ttgaaaatgc ttctgattta gctttttcaa tcatcttatc tctttgactg
    13561 accaattttt caagtttttc gtcatactct actttcagtt tttcaatctc ttcttttaat
    13621 ctttcagctt cttctctatc ttctactgct ttgattctat tcttttcaac attctgtaac
    13681 acatcttcta aagctatgtt ttctgtattt atatattctt tagcacgtga aatcacataa
    13741 tcacttagcc caagttttct agaaatctca aacgcatttg attttccggg aacacctata
    13801 agtaacttat atgttgggct taaagtttct atatcaaatt caactgctgc gttttctaca
    13861 cctggtttag taagagcata atttttaagc tcactatagt gagtggtagc tatacattta
    13921 gctcctacag aatttatatc ttctaatact gctattgcaa gggcagctcc ttcaacaggg
    13981 tctgttcctg ctcctaactc gtcaaatata actaaagagt ctgctgttac gttttgtaat
    14041 atagatacta tattcgtcat atgagatgaa aatgttgata gactctgttc aatactctgc
    14101 tcatctccta tatctgcaaa tacattatca tatacacaca tactacttcc ataatcagca
    14161 ggtatatgaa gtccactttg tgtcataagt gcaaatagac ctacagtttt tattgtaaca
    14221 gtcttaccac ctgtgtttgg acctgttatc accaatgtat ggaagtctct tcctaaataa
    14281 atggtatttg ctactacctt ctttttatcc agcagtggat gtcttccatt ttttatgttt
    14341 aaatatttat cctcatttaa agttggttct attcctctca tctgtataga aagttttccc
    14401 tttgaaaatg caaagtccaa tcttccaagt atctcttgat tagagattaa atcttcgctc
    14461 acttctccaa ccatagcaga aagctctgat aaaattcttt ctatttcttc ttgctcacct
    14521 agttttaact gtctcaattc attgttcatc tctactatag tcattggctc tataaaaagt
    14581 gtcgcaccag aagatgactg gtcatgcact ataccagcta cttgcgacct atattcagat
    14641 tttacaggta ctacaaatct atcacctctt agagaaatta ttgcatcttg taagtacttt
    14701 tgataagtag ttgaacttat tattgaattt aattttgacc taatggattg atttttttgg
    14761 gctattcttc ttctgatatc tctaagtgta cttgaagcat tgtcagatat ttctacttca
    14821 ctaattatag cattgtatat ctggtcttct atgtccttgt atacatatag agaatttgat
    14881 agagattgta ttattggata attaaaatct tcttcatcac tactagataa gctatttctt
    14941 aatcttctag ccactcttaa ggtatctgct atcataatca gacttcctgg gtcaagagaa
    15001 gcacctatat aagctctctt taccttatct tctatatcat gaataccttc caaccctact
    15061 gaacctctct ttataataat tgattgagct tcactagttt cttctagcat agatttcact
    15121 tctacaaaat cagtatttgg tactaaattt tctatatatt ttagacctaa agaagatgag
    15181 gctttcttct ttaacaaatc tattatttta ttgtattcta gaactcttaa cgatttctca
    15241 ttcattttct atattcacca tcctcgatat tttaactttt ttatttaatt ttaaaaatgt
    15301 atgttttcaa gcatttccaa taaaaactgc aagttttatt tctttttcat ttctaaaatt
    15361 attatatttt ttctctttta gatatatttt acacatattt tgtattatac tatgtatgta
    15421 gctatctata tattatacat aaacatgctt tatttgtaat ataatctgtt aaaaaatctt
    15481 ctttaatatt tttaaaggag tttattttag cttataaaaa aaaatagcta cttatataga
    15541 taaattaagg aggaacatga gtcatgggaa acgtattaga aggattaaaa ccagaaagtg
    15601 tttttaaaaa ctttgagaaa atatctcaaa ttcctagagg ttctggaaat gaaaaaggca
    15661 taagtgattt tttacttagc tttggtaaaa atttaggtct tgaaactatt caggatgaaa
    15721 gcttaaacat aataataaga aagcctgcta caaaaggata tgaaaattgt ccaggtgtag
    15781 ttcttcaagg acatatggat atggtttgcg aaaaagaaaa gaatgttgaa catgattttc
    15841 ttaaagaccc tataaaatta agaattgatg gtgacatgat atatgctact ggaactactc
    15901 taggagctga caatggtata gctgttgcta tgggtatggc tatattagaa gataatactt
    15961 tagagcatcc tgcactagaa gttttagtta ctgttaatga agaagatggt atgaatggtg
    16021 cagatgcact agaccctagc ttaattaaag gtcaatatat cctaaatatg gactccgagg
    16081 aggaaggata cttattagtt agctgtgctg gtggtaaaac ttgtgttgtt agtttacctg
    16141 ttgaatacaa ggaagttaaa ggtgacaaac aaggattatt agttgaggtt actggactat
    16201 taggtggaca ctctggtatg gaaattgttt tacaaagagc aaatgctaac aaagcaatag
    16261 ctagagtatt aagtgtattg aatgttgatt atgaattagc ttctgttgat ggtggtacta
    16321 agcacaatgc tatacctcgt gaagctaaat gtgtaatagc tgttaataaa gctgatgttg
    16381 aatctgctaa aaaacaaata aatgacattt taactgcatt taaacatgag tttactactt
    16441 ctgaccctgg catgacttac tcagtagctg aaacttctgt agacaaagtt cttactaaag
    16501 attgtaaaga aaaagttgtt caaatgtctt gcttaactcc tcatggagtt caatcagtaa
    16561 gtcttgatat agaaggatta gttgaaagtt ctactaactt cgctataatc gaaactaaag
    16621 aatctactat tgaattttta acttctgtta gaagttctgt tatgtctatt agagatgaaa
    16681 tcgctgatag aataagactt ttggctcaag ctttaggtgc taattacgac cttatagctc
    16741 aatacccagc ttgggaattt aaaaaaggct caaaattaga aaaaatatgc agtgaaactt
    16801 atgagaaatt aactggtaaa gttcctactg ttatggctct acatgctggt cttgagtgtg
    16861 gattattact tgataaactt cctcatgctg aagctatctc tataggacca gatatgtttg
    16921 atgttcatac tccaaatgaa catgttagta tcccttctgt agctaatgtt tgggattatg
    16981 ttattgaaat attaaaatct atgaaccaat attaaattta agttttgatt ctaagtagat
    17041 tttaatttta agtaatctat ataaaattaa ctctgtaaat taatactacg gttagtataa
    17101 tatttacttt caatattaac ttatagaaat aaagcctaat gatagataat aacatgtatc
    17161 attaggcttt attgtaattt aaatattatt aagctttatt ctgttttaaa attaattctt
    17221 atactatttt aaatctattt cttccttgtc tcttagaatc ataaagagca ttatctgcta
    17281 tttgatacag ttcatcatac tcttgaccag gctttgctat aactaccccc atactaatag
    17341 ataaactttc tccatttggc aacttaatga gatgaatatg attgtataca tcattacatt
    17401 tattaataag ttcttcctta tttattatat cattgatata aacactaaat tcatctccac
    17461 ccaaacgacc tactatatca ttttttgcaa aactttcatc aagtgccttt gcaacatcaa
    17521 taagtacttt atctcctaac aagtgaccat aagtatcatt aatcgattta aaataatcaa
    17581 tatctataat caataaagca ccattttttt cagttgataa attcaacaaa ttttgtgaag
    17641 ttaattttct aatatatgct gcattataaa tattggttaa actatccctt tgagccttat
    17701 ctaacaatct attcttttcc tctttttcag aatcaatatt acatattttc ccgattacat
    17761 acattggtat ttttctatca ttataaatta tttttgaagt aactctaatc caatgaaaag
    17821 tatcatcaag cataatagaa tacatttcag ttgttccatt ttcttgtgat tttattacat
    17881 caaaaaactt tttattatat tctttcctta ttttatctct ttcattttct atattgccat
    17941 tttcactttc cttatcattt ttatccaaac cataataagt ctcaataccc ttttctggca
    18001 tagaaattat caatttatct tgcttataat catactcaaa aaagtattca cttgtcattt
    18061 catacaactg agtatgtttt ttgagttcta aagatatctt ctcgttcata cttgtacgag
    18121 tatgtaaacc aaatgccata aatccaataa tacaaattaa taaactggct acaataaaaa
    18181 tagtctcaat tggattctgt tgcataatat aaagcaacga gaaatcttgt ctatatgtag
    18241 tattttggta gacaattgat tgcatttttt ctgatgaaat acttataata gctttattaa
    18301 atatattcaa taattcttgt ttatcttttt taattatacc aaaacaaata ctctttgctt
    18361 tataggtttg aggaactaga cgcacatttt tatacttagg ttgattcata tagtactgca
    18421 tagaataacc ttcgccataa gtgtaatctg catagccttt attaacagct tctatacact
    18481 cttctaaatt atcataccaa actatattct cttcaaactg accataataa ttaatacctt
    18541 tggctagagc tacacgtttt ccatctaaac tattctcatt taatttatta ttaatcatca
    18601 tagtatattg agtagaaaga aaaggccgag acatagctat attatgttca cgagagtatt
    18661 cataatcata aatcattcct gctacaatat caatttcacg ctttttagtc atgttttcta
    18721 aatcttcttg agattttaca ggcacaagtt caaattctaa gcctgtttta tcacatatat
    18781 gatttaacaa atcaattgat atacctctta attcacctgt atctttatct atattttgaa
    18841 atggtggttt gtttaaaagt actcctactt ttaatttttc tgtctcttta atgtaattag
    18901 tttcttcatc agataaaaac atttgattat tctctggtgt aaagtatttt tcatataaag
    18961 tagttgaaaa atatgggtct ttctgttcaa tattattaat tgctgagtta agcttttgag
    19021 ttaaatttgt actaccttta ggagtaatga aataaaatgg ttttgatgaa aattttgcta
    19081 cagtacgtac accttctatt gggttcatac tcacattaag aagtacatct gctttaccac
    19141 tctttagtgc ttctagttgc tcatcatttg ttttacaata taccaattca ggtgacataa
    19201 gattcatttt acaatactca tctaattctt taagtctagt atcagaattt tctattacag
    19261 caatacggat ttttttcaca tcttgtgaac tcattatgtt atcaatatct gtattttcat
    19321 ataatgcttg tagtactgta tttgctactc cataattatt ccctgcataa ttatatattt
    19381 tttgcattgg ttcattgtat aacatacctc ccattatatc aatttcacca ttttctaaca
    19441 tcttcattaa ttttgtaata gattcattta tctctccagg aacttgaaca aattcataat
    19501 tccatccagt atactgtgca atttctagta aatattcata tgtataccca aaatagttac
    19561 cttgctcatc tatttcagtt aaaccttttt gaataggata agcaacacga atggtacgat
    19621 tatcattacc tatagcgttg ataccaaaag aaaatatgca agaagtgaat atagatgtaa
    19681 ttacaataat taataaaagt aattttttta aattcactac acaatcctcc atatagttaa
    19741 gatttacagt ataaattact gcataaactt gtagacatgt aaaaatagat tagtatataa
    19801 aaggatatat aaatctactt agaaatttaa atatccttaa tatatacaat atatttaaat
    19861 tataactcat ttatatgtct attacaacaa atttaccctg ctaaatacct actctatatc
    19921 ccataatttt acaagttgta gtgaagttta agttctatct cacctcaaat ttagcagtgt
    19981 ttctatttac agttctttta tatttcacat ctggataacc caatataaat gaagtgataa
    20041 ctgcttcgtt ctcgctcatt cctaacagtt cttttatctt tggctctaca tttgatgcca
    20101 taacaaaaaa tccattataa caaattccta atccttgaga ataggccata agttccatat
    20161 tagatgcagc caatcctcca tctacataag cacttccacc tagagacata tcacctacaa
    20221 ctaccataag tagtggggca tcataaaata aagaatcatt tccgttctct ttgtatcttt
    20281 tgtacatttt cttaaatgta tttttataga tagaacgtac agggtcattg tcatcagtat
    20341 ctaatgccaa attataaaga ccttgtattg ccagttcttt cacttctttt agcttttctt
    20401 ttactaatat gtatcttata ggctgtctat taccacctgt tggtgtgtat ctaccagctt
    20461 ccactatgtt ttttattttt tcttcttcta cctctatatc tttatattgt cttatacttc
    20521 ttctaaattt aataaaattc aataactttt cgggttctaa ttcaaaactt tcacgattgt
    20581 attctattac ttcattttta tcaaatcctt gcatttctat tgcatctgtt gggcaaattg
    20641 ccatacagtg accacagtta atacagagaa tatttttaac ctttgcttta tcatccttaa
    20701 cttttattgc atttacaaga cagtctgatt cacacatccc acagcctaca catttttcta
    20761 aatttatgtc tatcattcca aattattcct ccttttaaaa aatttacttt agtataaaac
    20821 aaatagttgt ctaagtcaat ttttattttt ttaacaatat actagcctta actacacttt
    20881 aatggagaaa aatatacata aattggaact taaattagaa cttattcaaa gtaaaagata
    20941 aaagaagtag atgtctaaaa gtgaactttt tagttaatta gatattcttt attgtatgaa
    21001 atcaagtgga tatttatcat ttcaacaata aaaaaggctt acctctattt tggatatgtc
    21061 cctgtcaagt agacagacta aaaaaaggct atctttatgc actgagatag ccccttttcc
    21121 caactactat tgtttatctt aatattagtc aataaattta atttgctata acctgtaagt
    21181 tacattttaa tttgatgtaa ctttaaatta catttttaag taatatcttt aaattatatt
    21241 cttaaaatat atcattaaac tacattttaa ttaatctaaa aactatatct taattaatct
    21301 aagaaactta cattataatc ttttagtttc ccattatcat atacaatctt tgcactaaag
    21361 atatttccag tcttagccca atttaagaac agcctgtcac cttcccacat atttaaatcg
    21421 aatattttat cattatcaac ccaaattaaa tttccttctt tacaatcatt taaatctttt
    21481 tcagataatt caccttcaaa ctcatctgag aaatacaaaa acatatacca atcttcttca
    21541 tctttaaatt ttggaaaagt tatcaaccct ttatatgaca atgatttaag agtaagacca
    21601 gtctcttctt ttacttctct aattacacat tcttctggag tctctccttg ctcaaacttt
    21661 cctccaactc ctacatactt accttcatgt atatcatctt tctttttatt tctgtacaac
    21721 atcaaagtct tgtcatcttt ttctatataa caaatagttg taagtttcat gtatctcgcc
    21781 ttgctttctc ttttatattc tcaactaatt attttcagca ctttcaagca catcacttat
    21841 attcttcatt gcattaagag aaagctctgc aaattcatca aatggaatcc ctatatcttc
    21901 tatacttctc attgcatctc tatttacatt tgaagcaaat ctcgtttctt tcattctttt
    21961 aataacagac ttagtcttta cactggtaag ttttttatct ggataaacta aagctatagc
    22021 agttataaac ccagttatag ggtctgctgc atatattgct ttttccatta ggctagttct
    22081 tgtaactccc attccatcat gatgaccaag tattgctcta tacatttctt cgttaccgaa
    22141 gttttctttt ttaagcagtt ctactgttgt tgtagcatgt ccttcacata tttctcctgg
    22201 ctttcttcca actatatctg aatccaaatc atgtaaaaga cctgccactg cccactcttc
    22261 ttctttttct ggctctagtc ttttggctaa ttctctcata acagcttcaa cagcataaca
    22321 atgttttctc attctatcag tttctaaata cttaaataaa atttctaaag cttcttctct
    22381 cattttcacc aatccccctg ttttttcaca tatatgatat ttttatatat taatacacat
    22441 aaattcaagc ttttatatat attcatgtat atttttcatg ttatatctat tctacacctt
    22501 tatagtagtg tcctgcaact gttccaattt catctaattt cttatacaag tctgtagcct
    22561 tttttccaag tttataatta ttactcagta cctcaatgtg agcttcaata acctttttaa
    22621 ccatctcact atcttcaact gtaaaatcta tcctaaatac atctattcca atttcctcta
    22681 actcatatag attgtccaac atacaagtaa ccttcgaatt gtaaattgta cttctacaga
    22741 atatatcttg tgttatccta taacttgcat ccgtaaagtc tcttaaagca taactacttt
    22801 ccttacattt agcaactctc ttgtcctttt tacaatctct aacaactact cccataggac
    22861 agtattctgt aaccatcata ggagcatatc catatattac tgcttcaatt tctacatctg
    22921 tatattttaa agtttgttta atttcattta agtttagttc ttgtgacaaa caaactgtac
    22981 ttgctccctc ttctttgaag tgatttatac tttcactatt gaatacattt aagtagcaat
    23041 ctatatttaa gtcttttttc ttaaagtatt ccatagagcc ccagttacca atttgaacct
    23101 tattaattcc ttttatatta tccaatatct caaattgctt gtactcttta tttctaacaa
    23161 tccttggtgc tgaatagatt aattttttgt cagtgactgc tgtattagag tggttcttat
    23221 tcaaagtatc tattttactt gtatttgaca aagtatctat gttatttgta tttgaaccca
    23281 ttagttcttt aggagtacct aaagacgaag aagtatctaa atccatagaa atacttgaat
    23341 ctatagaaat atttgaatct atagagatac ttgagaccat ttgtaaagct tttgataatg
    23401 tatttatatc ttcataatag attaaatcta cattataatt taatactgct tctaattgct
    23461 ccaagttctt aactttaact ctaatcttag gagctgtatc aagttttttc tgtttattta
    23521 ctctatttgg ctggtatttt aatctattct tcttaaattt tctatctttt atctttattc
    23581 tttcttcatc taaaagctca atacaatccc ttctcatttg atttaacaca cttataggca
    23641 tacttacacc ttcatccagg tcaatttcta tctcttttaa cttatatggt gtatttccaa
    23701 gcttttgaat ttgtgtttct attttttctt tacttaaagc cacctttata gctttttcaa
    23761 ctattttgtc tccttctacc accgatttat ttccacaaaa atcacttata aaaagctctg
    23821 gctttttacc tagtttaata ctcacttttg cacgtatatt agtttttatg aactctttat
    23881 cttgctgaaa tgtagcttgt actctatcca ttaattcgct gtcagaagtc ttatatataa
    23941 gctgatttct ctttgcttct ccaacaaaat ctaattctat caaatcccct ttatgtgcta
    24001 ttgtagttat ctctccatcc tttattattc ttccaatagt acctccacct aagttaattc
    24061 catcaccttt cttaagcgta ttttctagca ttactctaag tcttttgttc tttctattat
    24121 aatctaaaac ttttccaata tatagccctt gattattagg tctattagag ttcattatat
    24181 ccttaccaac ttcacctaat atatatcctt ttgtaaactt tctattaaat atggtataca
    24241 aattatttat tatttcctca gaaatactta tttttttctt atctacaaat tcattaatcg
    24301 cttctctata tcctgaaacc acagtagcta catactctgg ctttttcatt ctaccttcaa
    24361 tttttaaaga taatacacct gcttcaatta ttttatccaa atcttctata gtacttaaat
    24421 ctctaggact caacaaataa tctccattac tttttactac ttctcctgta tttatatcta
    24481 tcaactcata cttttgtcta catggctgtg cacacctacc tctatttcca gacctattgc
    24541 ctatcatact actcataagg cattgacccg agtaacatac acataaagct ccatgtacaa
    24601 aaacttctat atctacagtt gtattttcac aaatccattt tatctcatca acatttaatt
    24661 ctcttgctaa aacaactcta tcaaacccta cactctgaag gtattttaca tcttctaagg
    24721 aatgtgctac catttgagtg cttgcatgta gttcaaagtc aggtaatagt ttttttataa
    24781 gtcttgccat tcctatatcc tgtactatta aagcatcaat atctatatcg tataaaaatt
    24841 ttacatactc tacaaaatct tctatttcat actgttttat caatgtattt acagtaacaa
    24901 agacttgcac tccccttata tgagagtatt taacagcctc aatcagctca tttctatcaa
    24961 agttatttgc agatgctcta gcactaaagt ctttaccacc taaatacaca gcatttgctc
    25021 cgttttgaac tgctgctttt aatgaatcaa aagagcctac tggtgcaagt aattctattt
    25081 ttttcatatt tttctcctct atttatactt gttaggttaa tataattata tctataactt
    25141 aaatatttgt attaaattta tatatttctt actatatttt aaattcttca atcaatttat
    25201 atattagtta tttatatttg gttcatttga gttaacatat acattattta ctatatttag
    25261 tatatttcta ttaacttata tattgattac tgtattttaa attcttcaat taatttatat
    25321 actgcttact aaatttaaaa cattttaatt aatttgtaca ctgtttacta tacttgaaat
    25381 acttctatta atctatatat tgcctactat acttaagaca ttttaattaa tttatacact
    25441 gtttactata cttgaaatac ttctattaat ctatatattg cctactatac ttaagacatt
    25501 ttaattaatt tatacactgc ttactatact taaaatactt ctattaactt atacattgct
    25561 tactatattt taaattcttt aattaatcta tgcaatattt gctatatata aagtatatca
    25621 aataacagct tcattttttt gtaaatttac agaaagttaa ttttcattaa atgaatcatc
    25681 tttattgata aacataattc caaagaccac tgccaaaata aaaaaacata ttagtattga
    25741 tttttccacg aaaatttttg taaaaaaagt tcctaaaata gctccagata taaagaatat
    25801 aataacagca taatactgta aactcttttt tatcataaaa atattcttag tatgtatata
    25861 atgaaataaa gtttctgtag cacttcttaa atttccagta cacattgtcg ttgcaaaact
    25921 attcccattt acttttctaa aactctctac ttgcattgaa caaataaaag aaatagcaac
    25981 atttacaaac atattaaatc ttcctctagg aataaatgaa acaataagta ttgtaatcat
    26041 ttcaattata atgataacct gacgccaatg aatctttgtc ttattatttg taaaatactt
    26101 tcttatcttc tcggctataa atacacctaa cataaatgcc aaaataggaa tcaaataata
    26161 aaatgattcc tttacattac cttctgctat attaagccca aacaaaacta tatttccagt
    26221 ttgtgcatta gcaaagactt tacctcttac cacataagta taaatatcca aaaatcctcc
    26281 tgttattgcc aacaaagaac ataaaaagaa tgattcagac atctgactct tgcttgtcat
    26341 atataaacct ctcgctttct aatgatagat acaaaatcaa aatcatttta gattctattt
    26401 ttcattgata taaaaaaatt atttatattt aaatattgtc tatatttata catcatttat
    26461 atttatacat taaaagaagc tgtctcaaaa aacaagagac agcaaatctt ttagtttatt
    26521 ccacattttt tgcatcatta tttaaccctg tacattttaa ctgtaaatca taagctttgt
    26581 tttgaaactc agaagctaag ttttcagcta tagtagctct ttcatttgct tcttcaagtt
    26641 gagtacttaa ctcctcaatc ttgtttttat aagcatctaa ctctgctcta gaaccttctg
    26701 tcgtattact aagttcgaat atttcttgct ttttattttc tataatctca attaactctt
    26761 tcatcttagt ttcagcttca cgattttctg cttctttttc tgctatcgta agctttaaag
    26821 acttgatttc taattgaagc tcttcattag atgctccaac cttcttactc aattcttcat
    26881 tagctttaat caacttctca ttctcatctg aacattcaaa taaaaggtct gatatattta
    26941 atgcagttaa tatcgcagca actgataagc tcaatttcgg gttttgacgt gttattttat
    27001 ccatttcttt gtctacaaaa tcagcaatac taatcataaa cttctctgat ttgtctccaa
    27061 ccattggata ttcagcgcca tggattttaa ccattacttt gttcatccta acctcccccg
    27121 acattagttg ttaatttgat cttaagttag catttaattt ttcgcttaat tcacttaata
    27181 tcttatcatg caccttagct acatcttcat ctgttagagt tttatcttta cttctataag
    27241 ttattgaata tgcaattgac ttgtatccag cttctatttg agaacctttg taaacatcaa
    27301 ataacttgta gctttctact aatccttgac cattttcctt tattatatct tctatttgtt
    27361 ttacaaatac atcatcttta acaataagag ctatatctct tgatgtagat ggatattttg
    27421 gtaatggcac ataattcttt gttctatcag aattatcaaa tacaaagtca atatctattt
    27481 cagcgacata aactctttga cctagattgt agttttctat aacatctgga tgcaattcac
    27541 ctaatgtacc tacatattta ttattataca ctattttagc acatctacca gggtggaagg
    27601 tagtattatt atcttgaggt tcaatttcat aacctttaaa tccgacattt acaagtatag
    27661 tttctatagt tccttttagt gcaaagaagt caacatcttt accatacata cctacacaca
    27721 ttctattttc ttccttaggt aattctgaat cttgtgggat gaatatatgt ccacactcaa
    27781 atgcagatac ttcttctatt ttatgagata cattagttga taaaacatct aacatatttg
    27841 gtattaaagt agttctcatt acagaagttt cttctcctaa tgggttaagt aatttaacaa
    27901 aatttctctt tgcattacct tctggtactc ttatcttatc tactccctta gggcttacaa
    27961 atgaatatgt taatatttca tttaatccta cagcagttga attatctttt aaagcatcca
    28021 tgaatttttg ttttgaagtt ttaattcctg ctgtcgtatt tccttctaat tgtacagaag
    28081 gtatattctc aaatccataa attctagcta tttcttccca tacatcagct tcttgttcca
    28141 tatctgttct aaagcttggt acatctattt ctaatttatc attagctacc aaattacatt
    28201 taaactctaa tgattctaaa attcctacaa actgctccat tggtacatct acacctaata
    28261 gatggttaat tctttgagga tttactacca attttttagg ttctggttta tttggatata
    28321 catctacaac accttttaaa acttttcctg ctcctaacat ttcaacaagc tgtgcagctc
    28381 tatttgctgc tatctctgca agattagggt ctaagtcttt ttcatttctt gaagatgctt
    28441 ctgacctaat accaactttt ttagctgtca ttcttatgtt ttctggtttg aaattggcac
    28501 tttcaaaaag tacagtcttc gtattagaag ttatttctga gttagcacca cccattacac
    28561 cagctaaacc aagtgatttt tctccatttg ttataactag catatctttg tctaatgttc
    28621 tctcaacatc atctaatgtt acaagtttct ctccatcttt agcatttctt actactattc
    28681 ttccagtctc tacttgattt atatcaaaag catgaagtgg ttgaccaagc tctaacatta
    28741 cgaagtttgt tatatcgact atgttactta taggtcttac tcctgcttct gtaagtcttc
    28801 tttgcatcca atatggagaa ggttctattt ttacatctgt aaccattcta gcaacatatc
    28861 ttctacataa atctggatta tctatctcaa ctttgaaatc tatctcttcg tcactttctt
    28921 ttacttcgat ttcaggatat tttacttttg ttcctatagt tgcagctgct tctctagcta
    28981 tacccatcat gcatttacaa tcaggtctgt ttgaagttaa ttcaaaatct attaaagcat
    29041 cttttaatcc taaaacatct tttatatctt ttcctaattc ataagaatct tcgtggtcta
    29101 aaatatatat accacctctt ttatactcct caatgtaatg ttcatctata cctagttcag
    29161 ctgctgaaca catcatacca tctgataatt cacctctgaa atcagtctgt ttgatttcaa
    29221 ctcctccagg taacttagaa ccatttacag ctactggaat ataatctcct tctgatatat
    29281 ttgtagctcc tgtaactatt tgaacaactt tatctccaat atctactttg gttacaacca
    29341 acttatcagc atttggatgt tgttttattt ctaaaatctt tccaaccaat atattttcta
    29401 tttcttcacc ataataatct attgtttcaa ctttagttcc tgtcattgtc attttatcag
    29461 cgaactcttt tacatccatg tctatatcaa catagtctct aagccatttt aaagatacta
    29521 acatctacat accctcctaa ttaaaattga tttaagaatc tcatatcatt ttcgaataat
    29581 aatctaatat catctatttc gtatttaagc attgcaagtc tttcaacccc aactccaaat
    29641 gcaaatccac tgtaaacttc tgggtctatt ccacaatttc taagcacatt tggatgaacc
    29701 atacctgaac ctaatatttc tatccaacct tcatatttac acattgggca acctttacca
    29761 ccacatttga aacaagtaac atcaacctct gcacttggtt ctgtaaatgg gaagttgtga
    29821 ggtctaaact tagttttgat atcagaacca aacaattttt caacgaagat atccatagtt
    29881 cctttaaatt ctgccatagt aacatctttt ccaacaacaa gcccttctat ctgatggaac
    29941 attggtgagt gtgtagcatc tggcgagtct gacctaaaac atctacctgg tgcaattact
    30001 tttattggta actcttgact tctcatagtt cttacttgaa ctggagatgt ttgagttcta
    30061 agtaataccc catcattgat atagaatgta tcgctcatat ctcttgatgg atggtcttta
    30121 ggagcgttta atgcgtcaaa gttgttttca acagtctcaa cttctggccc ttctgctata
    30181 gagaatccca ttccgataaa tatatctgtt acttcatcta taatttgagt tattggatgc
    30241 ttcttcccaa cctttaaaac ttttcctggt tgagtaacat ctatcacttc ctcttttaat
    30301 tttctttctt tttcaatagc atttatttct tcttttttag aatttatgct aagttcaatg
    30361 ttttctctta cctcattggc aaccttacca actactggtc tttcttcagc agataattta
    30421 cccatttctt taagtatggc agttatctca cctttttttc ctaagtactt aactcttaaa
    30481 ctttctacac tttctatgct ttgtgcttct tttatttcag ccaaagctgc ttcacgtaaa
    30541 gcaagtaatt tttcttgcac acatatcacc ctttcgtttt tttgtataaa aaaagcccct
    30601 caatccctgt ctagggacga aaggctatag tttcgcggta ccaccctagt agtttaacaa
    30661 tttaaaaatc atcaaaccac ctctaacaaa cttaacgcgt ttttgacgtc aaagcctact
    30721 gtaaaatttc agctctgtta ctccagaggg aacttctcat gacctcttag aaaacactcc
    30781 cagcctaggt gtttatctct ttactaagtt taatcaaaat actttcctct ttcattgcat
    30841 ttacaatatt atattgttta ttttagtatt atatcatttc cattcaaatt atgtgactat
    30901 ttttaatata tatccaatac ataattaatt
//
LOCUS       DAJMZY010000040        30103 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.040, whole genome shotgun sequence.
ACCESSION   DAJMZY010000040 DAJMZY010000000
VERSION     DAJMZY010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 30103)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30103)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30103
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.040"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            88..501
                     /locus_tag="OE968_001782"
     CDS             88..501
                     /locus_tag="OE968_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219063.1"
                     /translation="MSKSELGVKANLVSELMMLSYFFIDLLLQKFIFKGEGIWFTFII
                     LLAFWVCNLMYNKKYNDLVDEASKLMLLKVDQIASKIMLYSMFVIAVLFSVNHTRALD
                     ISNLDIGIMLLAVLFIQSLSKLILYIYFDKKGICN"
     gene            571..987
                     /locus_tag="OE968_001783"
     CDS             571..987
                     /locus_tag="OE968_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219064.1"
                     /translation="MSKSETGVRSKLILELLVITYFFIAVLATKYIFKGPSTASLPGL
                     SWLIVFGCYSIYNKKYNDLVDESSEFILSKVNKIAIKIMIYSIVIISIFFATPYTSNI
                     NISNLDTGIILIAVLFIQSLSKLVLYIYFDKRGICN"
     gene            988..1200
                     /locus_tag="OE968_001784"
     CDS             988..1200
                     /locus_tag="OE968_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCP7219065.1"
                     /translation="MAILMKTKIKEYREKLLMTQNELAKLVGVRRETIVHLENGKYNP
                     SLKLAMDIAKVFDTTVENLFEFIEEE"
     gene            2244..3077
                     /locus_tag="OE968_001785"
     CDS             2244..3077
                     /locus_tag="OE968_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HCP7219066.1"
                     /translation="MVIKKVFNNNVVFARDNSGQEVILMGKGIGFNKFTKDLVEIDKI
                     EKKFIFNNEESLSELHSLLDRIPLKDVELVSEIIQMGREELGDNLNDSILITLSEHIS
                     YMLKRMDEGLVFQSPLQWEIRQIYPNEYNFSKKAVEYLRKKLDKNIPDSEIAFITIHF
                     ANAQLETKDMQETLLLTKIIDNVLDIIKYHYGIEINEYSFDYTRFISHLRCFIKRQLS
                     GENTNVDTSLLDIIKMKYKSDYNCAKKVKNFLEKTYKWKISENELLYLTLHLNRLSNI
                     K"
     gene            3203..5044
                     /locus_tag="OE968_001786"
     CDS             3203..5044
                     /locus_tag="OE968_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HCP7219067.1"
                     /translation="MKFERESEEIIKYVGGKENIISLVHCATRLRFKLKDTSKTNKEE
                     LLKMKDVLSVVNSGGQYQVVIGNKVTDYFETIIKKAVLQGQNTEEQGEKVSIVSKIFE
                     SISGAFSPLIPALAGAGMIKALLTILTTMKWMSDTSSTYAILSAAGNAVFYFLPIFLG
                     ITLAIKLSANPYVGGVIGAALLDPNFTALIGAKGGANFFGMPVTAIDYSFGVFPIFVA
                     IFIYYYVDKLLKKIILKDLQLFLVPMISLLVMVPLTVILFGPIATNVGDIISNIFMGL
                     FEFNRVIAGAAIGIAMPFLAVLGLHWGFTPITLQNLATMGGDPIEGAAVAAVFAQIGI
                     AIGLFMKVRKSKKNSELKVLAGSTAVTGILAGVTEPIIYGIILRYRRMIPVLAIAGGI
                     GGGICGVFGVTCNAYVFHNIFSMPVYTPFLGYILGIGTALVLGAVLSYFFGLSKEECE
                     EGNEEVAFDEDDGIEEILSPIEGLQIELSEVEDEVFASGTIGNGMAIIPSKGEVVSPV
                     NGTITTIFPTKHAIGITSDKGVEILIHVGLNTTMLDGKYYTTHMNAGDKVKKGDRIVS
                     FDKDKIEGEGYSIVTPIILTNTNDLADVIVKENKHIKIGTPVIKVVY"
     gene            5067..6500
                     /locus_tag="OE968_001787"
     CDS             5067..6500
                     /locus_tag="OE968_001787"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003243232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HCP7219068.1"
                     /translation="MKSNQEFLWGGAVAAHQVEGGYNKGGKGISIADVMTAGTHTISR
                     KITDGVIEGLNYPNHEAINFYENYKEDIRLFAEMGYKCFRTSIAWTRIFPKGDESTPN
                     EDGLKFYDDLFDELLKYNIEPVITLSHFEMPYHLVKNYGGWRNRKLIDFFVNFCEVVM
                     NRYKDKVKYWMTFNEINNQSITTNPIYAFTNSGIIYEEQEDKEEVMYQAVHYEFVASA
                     KVVKIGHEINPEFKIGCMVAAMPSYPYSCNPEDMIKFVESNREQLMFTDVHVRGHYPR
                     HTLKLWERKNYNLDITEEDKKILKEGIVDFIGCSYYLTTVVTADKTMKTTGNDSAGKA
                     DVVENPYLKISDWGWNIDPVGLRFYLNQLYDKYELPIFIVENGFGAEDVLKSDNTVDD
                     DYRIEYLASHIREMKNAIEIDGVDVIGYTVWGCIDPVSFTTGEMKKRYGFIYVDKNND
                     GSGTLKRYKKKSFDWYKNVIKFNGEIL"
     gene            7205..8083
                     /locus_tag="OE968_001788"
     CDS             7205..8083
                     /locus_tag="OE968_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HCP7219069.1"
                     /translation="MLINMKEMLKVAQENQFAVPAFNIGSGQILKAVVQSANEKNAPV
                     ILAIHPNELSFLGDSFVASCIEEANKSKVPMVIHLDHGENKEQILRAIRCGFTSVMID
                     GSHLPYEENVAISREIVEIAKGLNVSVEGELGTIGTTGTSSEGGTDEIIYTDSKLAKD
                     FVEKTGVETLAIAIGTAHGIYPKGFKPELKLDLLKEIREVVDIPLVLHGGSSNPDEEI
                     AQAVKLGVCKINISSDVKSAYYKKCRELLEQNPSLYEPDTIYPPCIKSAREVIEFKMN
                     LFNAIDKLKCFYKNKN"
     gene            8119..10014
                     /locus_tag="OE968_001789"
     CDS             8119..10014
                     /locus_tag="OE968_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HCP7219070.1"
                     /translation="MIGKILRSDCIVLDKQLQTKKDVINYMANHLYHGNYINNKEKFI
                     ADINKREKESSTNMGNLIAIPHAKSNVVNQPVMMYLRTDREITDNDGQKLRSFFMIAV
                     PESGSDEHLKIISKLATYLMEENFLKHLLSAETPYEILSIFNNKAAESGDFSNNQNKG
                     LIVGITGCPTGIAHTFMAKKALEEAGQELGYEVKIETHGAIGVENKLTKEDIKRAEYV
                     IIACDKEVQLSRFIGKKVLQKKVVDAKNVSLAKNLIINAENGMAKEIKPGGKTLEDSK
                     EMLQGSEKKGVYKHLMSGVSEMIPFVVIGGIGIAIAFMFGIFASDPTHETYNPIAGFF
                     GQLGGDSAFKLFIPILAGFIAKSIAGRQGFAPAMIAGFMAVIGGSGFIGGMVAGFATG
                     YIALGVMKITENLPDVLKGVNAVLICPLLIAFTSGAIMFFVVNTPASWLNEALQSWLQ
                     SMSGTNKVLLGAILAGMMASDMGGPINKTASAFGLAMFSSNIFEPSAALMVGGMVPPL
                     AISLAMLIFKNKFTKEERKSSLPTAIMGASFITEGAIPFAAADPLRMIPANIIGSCIG
                     GAICMSLDITLMAPHGGIFVIPFACSAPVAYIACILIGTVITALIIGVTKPTIRSENS
                     EVELLGA"
     gene            10282..12189
                     /locus_tag="OE968_001790"
     CDS             10282..12189
                     /locus_tag="OE968_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HCP7219071.1"
                     /translation="MLVSRQIEFLKLILNENKYRPIKYFKDKLNVSDKTLQKDLKMIE
                     KYLETFNIKIDIKRGYGILIEDLAKKNIDLINSLNIQSKENKSLSVEQRRMEILKYLL
                     LNSNNITSINQLADKYYVSKTSIVNDFKYIEAWIKEYNLKLNKTLEGTKIIGKEVDIR
                     KSIAKMMDDLLDENYEQHDISELTRLDSATFSALINLFDIDSIIFVETIITELEYNLG
                     YTINQPYYINLITHILICLKRIEEGNQIESQEEREISVDNLDELVYKNVSTLIDKIEN
                     RYRVKITKDEIMYIYIFLVSSGFSSENNSSYNDESDRLSESEKVSSIMIENMSRFLNI
                     NLKNDDLLQKSLASHVRPMLNRLRYDIQIKNPLLGEIQERFSDVLGLCMMTINIMTEY
                     DNLKNISIDEVSYLATYFQAAIERNMSSKRVIVVCHTGYGTSQLLAARLKREFPEWTI
                     VDIVPMHQLSKRNLDDVDFVISTVNLDLKDKLHIVVSVLLMENDINNIKNALLSKPKK
                     SMNLDTNLLGMYLEDNIYFNFDVAQMESLIGVNLGSKYESISLGKDLNIYIHKQSKLN
                     KGIMNINNVTRTIDIYLEISNQSFLKNILMEISNLYRQKNYINYIIDCKSKEDIKILF
                     KNNLLEKTNGN"
     gene            12179..12628
                     /locus_tag="OE968_001791"
     CDS             12179..12628
                     /locus_tag="OE968_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HCP7219072.1"
                     /translation="MEIREILTEESIILDLKSTTKEGIIQELVDKLYDTGSITLKSKF
                     IKALKHREKIGSTSIGYQMAMPHGKTKYVKKASIVIGKSKKGVDWPSIDGLPVKVIIM
                     FAMPQSGGNEDMILISKIAYILGGKNIGERLLNANTKKEILDIFYEV"
     gene            12728..13615
                     /locus_tag="OE968_001792"
     CDS             12728..13615
                     /locus_tag="OE968_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HCP7219073.1"
                     /translation="MAIYLEMPKLIHEFPFRSLSNEGEVLTTPHWHKEIEILLITEGV
                     VNLFINDKPMQLKKGEIVIIKGGDIHYILPSPGSERLVFQFDISFFNDLILLNEEKES
                     LINLFSSIKKCSRDWSAKIRKSVFDILIDIYNEDLYKIEGYSYAIKGKMYNLIPILYR
                     QIPREIEENTVEYEINSKEILERLNNIFKYVEKNYKQPIKLEDVSYEVGFSVYYFTKF
                     FKKNTGKTFITFLNEYRLEKAKWILLNNNISIVDLVEEVGFGSTKTFYRVFKEKIGVS
                     PLEFKKRYNSLEKKGSVSK"
     gene            14018..15466
                     /locus_tag="OE968_001793"
     CDS             14018..15466
                     /locus_tag="OE968_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HCP7219074.1"
                     /translation="MKLGKDFLWGGAISANQSEGFYLDGGKGLSQFDKLPLNDKRLKD
                     VCLDEDNILNENNQYYPSHIGIKFCENYKEDIAMLAEIGFKCFRFSISWSRIFPTGEE
                     SEPNEKGLQLYDNIIKELKKYNIEPLITISHFDIPYSLVEKYSGWADRRVVNLYVKYA
                     EILMKRYKDDVKYWIPFNEMNMIMHIPYIGAGLTFIADENQLQKKYQAAHHQLLANAK
                     TIEIGRYINKEFKFGCMLAAGKTYPYTCKPEDVFATLEHERHNLFFSDVQVRGVYPSF
                     MNYYLKSNQIKLIIKEEDLSTLKDNTVDFVSFSYYSSACSSARAEGLEKSKANGPETI
                     KNPYLPKSNSVWQNDPVGLRITMNQLYERYQLPLFIVENGLGTQDIVNEDGKIIDDYR
                     IDYMKEHIKNMIIGVNEDGIELIGYLMWGCIDVTSVSEGKMTKRYGIIHVDSDDYGRG
                     SFKRTKKQSAFWYKKVIETDGEILFNDMETHA"
     gene            15492..17882
                     /locus_tag="OE968_001794"
     CDS             15492..17882
                     /locus_tag="OE968_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HCP7219075.1"
                     /translation="MSLIFTTKDQLIEQGFSKDTIKSNETLFTLANGHLGVRGNIEES
                     DFNNEYVDNMGTYVNGFYEESPITYGESAYGYAKQNQTICKLPNAHIVNFSIEGDCFD
                     LSKGITSEHSRILDLNEGILKRSFIWENSRGRKVKVSIERLVSQDIEELMMISYTITP
                     LNFNGKIKFKNKMENSMEKFNCEKVEDPRVASINKKQFKINVKKYNNKYFMNLVTERS
                     RLGLWCGFDSYITCGNITNETYNVSDECIEREIEVYAKKDERLNLEIVVGYSRVYSDL
                     NLNEERLKSLECLESLKCLESEAHLKSLELVLREACNIGFDKVKNIQRKKMNEFWTTS
                     DVEIEGDKTLQLGIKTNLFHIYQSVGRDGKTNISAKGLTGDGYEGHYFWDTEMYILPF
                     FIYTQPSIARALLDYRYSILDASRERARELGINKGCLYSWRTINGNECSAYYPAGTAQ
                     FHINADIAYGIRTYFEATNDEEFMMQNGLEILIETARFWVEFGDYIESKNNKFCINGV
                     TGPDEYTAIVNNNYYTNLMAKYNLIYAVQMVDKFKHNLFSNEVFRKVKLQEYEVKNWI
                     NAAQNMYLPYDEEKKISKQDDSFLEKSVWDFKNTPKEKYPLLLHYHPLTIYRYQVNKQ
                     ADTVLSALLFPDEFSLEQKKRDFEYYEKITTHDSSLSRSIFGMMASEIGNHEKAYNYF
                     MDTALMDINNLQKNTSDGIHAANMGGTWMSLVYGFAGMKIKNDKLSFEPRIPKHWKNI
                     KFNILFRDNLVSVNIEEYKSYYKLIKGRNITILHDNKEIKLSKNIIEVNNCFKGSN"
     gene            17884..18555
                     /gene="pgmB"
                     /locus_tag="OE968_001795"
     CDS             17884..18555
                     /gene="pgmB"
                     /locus_tag="OE968_001795"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HCP7219076.1"
                     /translation="MKAVLFDLDGVITDTAKYHFEAWHEIAKSLDIEIDETFNEKLKG
                     ISREESLDKILLSANKVDSYTKEEKLKVCEEKNNIYIKLINSLTYKDILPGINELIKE
                     LKKNNVKLGIASASKNAPRILESLGIKDEFDCIVNPSLLKRGKPYPDIFIEGSKILNL
                     KQYDCVGIEDSYSGIKAINAANMTSIGVGKKEVLGKCDHIVEDTSLLNYNTLLQAWSK
                     KINLD"
     gene            18594..19964
                     /locus_tag="OE968_001796"
     CDS             18594..19964
                     /locus_tag="OE968_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HCP7219077.1"
                     /translation="MKNKYEEVAQLIIDGLGGKDNIIDLTHCMTRLRFILKDEKKVNA
                     DKLKSIDKVVGVNSTSTQYQVIIGNEVGVVFNAIINKGINTTGDIKSDIKNKNKKNSI
                     LNNIIDTITGCMTPMIPALTASGMIKVILSLCTTFNWLSSNSSTYRVLDIIGDVAFYF
                     MPIILAINAAKKFNVNTSIAVIVVGVFLHPNFSAWVSSGDPISFIGVPIQDVIYAASV
                     IPALLTVWMMSYIEKFIDKLTPSMLKTILNPTLVLLISAPIALIVIGPIGNFLGEGLA
                     SIINLLQGRLGFIMVCLLAAAMPFIVMTGMHHALTPIFISAFATTGQESLILISQVCA
                     NLAQGGATLAVALRSKDSKMKQLASAAWISAIMGITEPALYGVTLKLKKPAMLASIGA
                     GIAGLFAGITHVTLYVPQNSIMAVLGLSGEKGISNIVNGLIVIFIALVAPFIMTYVFG
                     VEKNVK"
     gene            20311..21153
                     /locus_tag="OE968_001797"
     CDS             20311..21153
                     /locus_tag="OE968_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HCP7219078.1"
                     /translation="MIINKILNNNVVITLDDNDEEVIVMGKGIGYQKSKGNLIDKTKV
                     NKVFRISNKEISNKLQELLNNIPIEHMKLSSEIIEYAQIKLNKKLNESIYISLSDHTY
                     SAIQRMKEGINVKNAILWEIKRFYKEEFEIGMKALDIIENKTGIKLPEDEAGFIAFHI
                     VNAQLSEGHTLASDITKLIQEVLSIVRYHFRIEFHEESVFYYRFIMHLKFFAQRLLLD
                     SAHEGETDKELLSIIKSKYNKEFECVVKIKNFIKKQYNYILTDDELIYLTIHLAKVVK
                     DSNM"
     gene            21298..23226
                     /locus_tag="OE968_001798"
     CDS             21298..23226
                     /locus_tag="OE968_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HCP7219079.1"
                     /translation="MGKYKQLAQEIVNNVGGKENISGLVHCITRLRFTLKDESIANDN
                     VLKNMEGIVTVMKSGGQYQVVIGNHVEAVYKDVVEIIGLDDSSTSSETKKSGNILDKG
                     IDIISGIFQPVLGIMAACGMLKGFNALFVAMGLYSDVSGGYMVINAAGDALFTFLPLF
                     LGYTSAKKFGLKPMLGLALGAAVCYPAIQGSSISAGADVMYTLFKGTMFASPVYIDFF
                     GLPIVSIDYTGTVVPIIFIVYFASRCEKLFNKCVPNLVKFFFVPMLTLLITVPVALIV
                     IGPIATFGSTLISQIVISIRDFSPLLAGAIVGFTWQILVIFGMHWGFIPVYINNVMTL
                     GYDNVMMPFFACTFASSAVVLAIFFKTKDKKLKEMAIPNFISGIFGVTEPAIYGILLP
                     LKKPFIISCIASGIGGAFYGFFNLRKFITGGMGIFELPAMIEPDGGMGNLIVALSGIA
                     ISMVVAFVLTMILYKDEKVEESKKVRNKGKEEIKEVKSTKLEREIVTSPIKGEVLKLS
                     DIEDAAFASGVLGQGVAIIPSDGKVVAPVDGVVTTLFPSLHAIGILSDTGVEVLIHIG
                     LNTIQLEGRGFEACIKQGDRITKGQTILNFDVYAIKELGYSTVTPIVITNSSQFLDVV
                     ETESKNIELEDNLITVLF"
     gene            23287..24714
                     /gene="ascB"
                     /locus_tag="OE968_001799"
     CDS             23287..24714
                     /gene="ascB"
                     /locus_tag="OE968_001799"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HCP7219080.1"
                     /translation="MSFKNDFLWGGATAANQCEGGYNEDERGLANVDVCPTGKDRTAV
                     ITGKLKMFDFDDEHYYPAKTGIDMYHNYKEDIKLFAEMGFKVYRMSIAWSRIFPKGDE
                     ETPNEKGLQFYENIFKECKKYKIEPLVTITHFDCPMHLVKKYGAWRNRKMIGFYEKLC
                     NVIFRRYKGLVKYWLTFNEINMILHAPFMGAGICFEEGEDVEKIKYQAAHHELVASAI
                     ATKIAHEVDSNNLIGCMFAAGSVYPYSCNPNDVWEATKLDRENYFFVDVQSKGKYPNY
                     ALKYMEQKGITPEMEPGDIELLNKYTVDFISFSYYNSRCVRTDENADDMAEGNIFTSA
                     KNPYLSYSQWGWPIDPLGLRITLNHVYDRYEKPLFIVENGLGAKDIADENGYVEDDYR
                     IDYLREHIKAMHDAVSIDGVDLLGYTTWAPIDLVSAGTGEMEKRYGFIYVDRDNSGNG
                     SLRRMKKKSFEWYKKVIASNGEDLY"
     gene            25161..25937
                     /locus_tag="OE968_001800"
     CDS             25161..25937
                     /locus_tag="OE968_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HCP7219081.1"
                     /translation="MKYQHIIEVDKELCIGCGLCKNDCPVNNIIIENKKSVIKKQDCL
                     MCGHCAAICPTKAITLTGFDEPPIELTNKPKLDSDELLMAIKSRRSIRKFKDKEVSSE
                     IIKQIIEAGRYTPSAKNSQDVSYIVLDNKKSIYENEAVKFFRKIKPIANIAIKYSKEV
                     EIDDNFFFKHAPIAIMIITKDKISGSLAASNMALMAESYGLGVLFSGYFSDVANNSPK
                     LKKLLGLKRSNHVLTTLVIGYPDVKYRRTAQKEVATVRYL"
     gene            25953..26318
                     /locus_tag="OE968_001801"
     CDS             25953..26318
                     /locus_tag="OE968_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HCP7219082.1"
                     /translation="MEKECQQRMQEITSKFKECRKAISAMGDETRQLILIALLESDFN
                     GIRVGEITKKTHLSRPAVSHHLKILKEAEIVNLRREGTKNYYYLDSKKSQWKSLTELI
                     NLIFVGIQHISENDIRKGD"
     gene            complement(26484..27233)
                     /locus_tag="OE968_001802"
     CDS             complement(26484..27233)
                     /locus_tag="OE968_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440038.1"
                     /note="N-terminal region resembles flavodoxins. C-terminal
                     ferrodoxin region binds two 4Fe-4S clusters; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EFR1 family ferrodoxin"
                     /protein_id="HCP7219083.1"
                     /translation="MILYFSGTGNSRYVARKIAQELNDELISLNQLIKEEKTDELISA
                     DKPFIFVCPTYAWRLPIVVTDFIKETKFLGSNRVYFVMTCGGDTAKSINYIQKLCKYK
                     EWQLKGMAEIKMPENYIALFSTTDKETSKQMIKEADKQIYRIISDIRNENEFETITPS
                     GLGGTIKSGIINTVFYKTIISAKGFHYTDKCIGCGKCVELCPLNNINLKNKKPVWKNN
                     CTHCMACICGCPTEAIEYKNKTQNRERYYLE"
     gene            27691..28116
                     /locus_tag="OE968_001803"
     CDS             27691..28116
                     /locus_tag="OE968_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCP7219084.1"
                     /translation="MINENLKSLRKINQYTQEELAEKLNVSRQSIAKWESGESIPDIC
                     SCIKLAKLYNVKLDDLVNHSEEKTGIIVPPKGKFFFGAVVVGERGQIVIPKEAREVFN
                     INAGDKLLVLGDEERGLGIVHQRDLINFIGHVGVVRKEE"
     gene            28148..29335
                     /locus_tag="OE968_001804"
     CDS             28148..29335
                     /locus_tag="OE968_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosyltransferase"
                     /protein_id="HCP7219085.1"
                     /translation="MSKIVFFSIPAYGHTNPTIEVVRELVDRGNEVLYYSFNEFKDKI
                     EGAGAKFICCDKYLPELLPGDEKKIGKDFPGLIEMIVDTTISLDEKVCRELKDFNPDC
                     IVSDSLSFWGKLFAQKLNIPYVCSTTTFAFNKHTAKLMKQNFIEIIRMIFGVRRINKK
                     IKLLQRKGYEVKNFISIVSNDNDTDTIVYTSKEFQPMVETFSSKYSFVGPSVSKLIIE
                     PKERKRKLIYISLGTINNKNVSFYKNCISAFKDSDVDVIMSVGRSTDIKSLGNIPNNF
                     EVKNSVEQIAILQKTDVFVTHSGMNSVNESLYYGVPMVLFPQHSEQRMVAKRVVHLGA
                     GIMLKEDKSESIKKAVFQVINDNEYKENATKLSKSFYNAGGSKKAADVILQIICNSRQ
                     VDI"
     gene            29527..29931
                     /locus_tag="OE968_001805"
     CDS             29527..29931
                     /locus_tag="OE968_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3139 domain-containing protein"
                     /protein_id="HCP7219086.1"
                     /translation="MKKYKVIFIVLIIGIISVTGFVVYKNCIKPWKDAETYIDKYMVK
                     QDISKDNIKSITKEKAKKASYEGILYKVYYKDDPRYEYQYFYSDNYYALYVNKVMLQI
                     YDMENNNKLLRSNEELKSVKYPLIYLKYKPDK"
BASE COUNT        11946 a         3077 c         5302 g         9778 t
ORIGIN      
        1 caatattcta ttgcaattta tttggaaaag ttatatattt ataacataag gtgttataaa
       61 tatataactt ttaaggggtg attttatatg tctaaatcag agcttggtgt taaggcaaat
      121 cttgtttcag agttaatgat gctatcctat ttttttatag acttgttatt acaaaagttt
      181 atttttaaag gagaaggtat ttggtttact tttataattt tattagcttt ttgggtgtgc
      241 aatctcatgt ataataaaaa atataatgat ttagttgatg aggcatcaaa acttatgttg
      301 ttaaaggttg atcagattgc atcaaaaata atgttatact ctatgtttgt aatagctgtt
      361 ctcttttcag ttaatcatac aagagctttg gacatatcaa atttggatat aggtataatg
      421 ctcttagcag ttttattcat acaatctttg tcaaaattaa ttttgtatat atattttgat
      481 aaaaagggaa tatgtaacta agtaataata tttatgaaaa caaaaattaa aaaatataga
      541 gaatatataa cttttaagga gtgattttat atgtctaaat cagaaactgg tgtaagatca
      601 aagctcatct tggaattact tgtaataact tattttttta tagctgtatt agctactaaa
      661 tatattttta aaggtccaag cactgcttct cttccagggt tgagttggtt aatagttttt
      721 ggatgttatt caatttataa taaaaaatat aatgatttag ttgatgaatc atctgaattt
      781 atactatcaa aggttaataa gattgcaata aaaataatga tatattctat agtaataata
      841 tctattttct ttgcaacacc ttatacaagt aatataaata tatcaaacct agatacaggt
      901 ataatcctca ttgcagtttt atttatacag tctttatcta aattagtgtt gtatatatac
      961 tttgataaaa gggggatatg taactaagtg gcaatattga tgaaaacaaa aattaaagaa
     1021 tacagagaaa aactccttat gacgcaaaat gaacttgcta aattggttgg ggtaagacgt
     1081 gagactattg tacacttaga aaatgggaaa tataatcctt ctttgaagtt agctatggat
     1141 atcgctaaag tattcgatac tacagtagaa aatttgtttg aatttattga agaagaatag
     1201 tggaaagttt ataaacattt ataagatgga taatgaaata tagttattta attattaagt
     1261 ttattaaaaa tatttatata atatgtgatt aaggttagat tataattgtt ttaagataat
     1321 aagaagagta ttataaatga taaaaaatag tgaatataca gttaattaat aaacaataga
     1381 taaaaattta aagtttaaat gtaaagagga tgtataattt tatgaaatct aataagacac
     1441 tgttataatc gctatgtaag gaaatcatat tagaattttc taagaaaaca gttaagaatt
     1501 tggaagtaag tatgtgttat ttatatactt ctgaaacata taaactaata agtgaggttg
     1561 tatcagatat gtcttgtaag ggtaatttct tcaggttcat caactatcat aactctacag
     1621 agggtataag atatgctttg taagggtaat atatgcttga ttcaagaatt agtgttataa
     1681 aatggattag cataccaaaa ggtctattaa agatatacag ttaaaaagct atatagtaag
     1741 ttaggtaagg ttaataatcc aaacaatgat ttgatgatta aactgtttag agccttagat
     1801 acaacagtaa aagaattatt ttttaataag gagaagtaaa agataaaaga aaatcaaaac
     1861 ttaggcagtt attgtagtta caaaataaag gatttcctta tatatggata aataatcgag
     1921 tatatataat aaaaaatata tgaccttaat tttgttatga aataacttca aaacttattt
     1981 tagcatgttt agattatata aatcatataa aaaaagtaga atgagtgaat acttatgaca
     2041 ataatctagt agagatatac atgaaattat atattgacta agtacagtta ttattttata
     2101 atgaaaataa agttatcata cagataaata aacggatcgt tactgagata gatgtaatca
     2161 ggcgtgacct aaaaattcta gtaaatgctt aaagtattat tagtcttttt taggtctctt
     2221 tttgtttaca gtggaggtag tttatggtta taaagaaagt atttaataat aatgttgtat
     2281 ttgccagaga taattcagga caagaagtaa tattaatggg aaaaggaatt ggatttaata
     2341 aatttactaa agatttagtt gaaatagata aaattgaaaa gaaatttata ttcaataatg
     2401 aggaatcatt aagtgaatta cattcactac tagataggat acctttaaaa gatgttgagc
     2461 ttgtaagtga aattattcaa atgggaagag aagaattggg tgataatctt aatgatagta
     2521 tattaatcac attatcagaa catataagtt atatgttaaa aagaatggat gaaggattag
     2581 tatttcaaag cccgcttcaa tgggaaataa gacaaatata tcctaatgaa tataatttta
     2641 gtaagaaagc tgtagaatat ttaagaaaaa aattagataa aaatattcct gattctgaaa
     2701 tagcatttat tacgatacac tttgcaaatg ctcagttaga aacaaaagat atgcaagaaa
     2761 ctttattgtt aactaagata attgataatg tattagatat cataaagtat cactatggaa
     2821 tcgaaataaa tgaatattcc tttgactaca caaggtttat aagtcattta agatgtttta
     2881 taaaaaggca attaagtggt gagaatacaa atgtagacac atcattgtta gatataataa
     2941 aaatgaaata taaaagtgat tacaattgtg caaaaaaagt aaaaaacttt cttgaaaaga
     3001 cgtataaatg gaaaattagc gaaaatgaat tgttgtactt aacattgcat ttaaatagat
     3061 tatcaaatat aaagtaaata gtgtaggatt gttactgttt ggcaggcatg acctaagttg
     3121 gtataattag tttttaatat ctaattgtat tgatttaggt ctatttttat acataaaatt
     3181 atgaaaatgg aggatagatt gtatgaaatt tgaaagagag tctgaagaaa ttataaaata
     3241 tgtcggagga aaagaaaata ttattagttt agttcattgt gcaactaggc tacgttttaa
     3301 gctgaaagat acttcaaaaa ctaacaaaga agagttatta aaaatgaagg atgtactatc
     3361 tgtagtaaat agtggaggac aataccaagt ggtaattgga aataaagtaa ctgattactt
     3421 tgaaactatt ataaaaaaag cagttttaca aggacaaaat actgaagaac agggagaaaa
     3481 agtttcaata gtttctaaaa tatttgaatc aatttcaggt gcattttctc cattaatacc
     3541 tgcactagct ggagcaggaa tgattaaggc actgcttaca atactaacta ctatgaaatg
     3601 gatgtctgat acaagtagca cttatgctat attatcagca gctggaaatg ctgtatttta
     3661 ctttttacca atattcttag gtattacctt agctataaaa cttagtgcaa atccatatgt
     3721 tggtggagtg ataggagcag ctttgttaga tcctaatttt acagctttaa ttggagcaaa
     3781 aggtggtgct aacttttttg ggatgccagt aacagcaatt gattattctt ttggtgtatt
     3841 ccctatattt gttgctatat ttatttatta ctatgttgat aagcttttaa agaagattat
     3901 attaaaggat ttacaattat tcttagtacc gatgatatca ttattagtca tggttccttt
     3961 aactgtgatt ttatttggac caatagcaac taatgttggt gatataatat ctaatatttt
     4021 tatgggatta tttgaattta acagagtaat tgcaggagct gcaataggta tagctatgcc
     4081 attcttagca gtattaggac tacactgggg cttcacacca attactttgc aaaacttggc
     4141 tacaatgggt ggagacccaa tagaaggtgc agctgttgca gcagtatttg ctcaaatagg
     4201 tattgcaata ggtttattta tgaaggttag aaaatctaaa aaaaattcag aattaaaggt
     4261 attagcaggt tcaacagcag ttacaggaat tttagcagga gtaacagaac ctataattta
     4321 tggaattata ttaagataca gaagaatgat tccagtattg gctattgcag gaggtattgg
     4381 tggtggtata tgtggtgtat ttggtgttac ttgtaatgca tatgtatttc ataatatatt
     4441 ctcaatgcca gtttatacac cattcctagg atatatatta ggaataggaa cagcattagt
     4501 gctaggagca gtattgtcat atttctttgg attgagtaaa gaagaatgtg aagaaggtaa
     4561 tgaagaagtt gcttttgatg aagatgatgg tatagaggag atattatctc caatagaagg
     4621 cttacaaata gagttatctg aagtagaaga tgaagtgttt gcatcaggaa ctataggtaa
     4681 tggcatggca ataatacctt caaagggaga agttgtgtct cctgtaaatg gaacaataac
     4741 aactattttt cctacaaagc atgcaatagg aattacctct gataaaggtg tagaaatatt
     4801 aatacacgta ggtcttaaca ctactatgtt agatggaaag tattatacta ctcatatgaa
     4861 tgcaggagat aaagttaaaa aaggagatag gattgtttct ttcgataagg ataaaataga
     4921 aggtgaaggg tatagtattg ttacaccaat aatactaact aacacaaatg atttagcaga
     4981 tgtaatagtt aaagaaaata aacatattaa aattggaacg cctgtaataa aagttgttta
     5041 ttaattatac tggaggagat atttctatga aatctaatca agaattttta tggggagggg
     5101 cagttgctgc ccatcaagtt gaaggtggat ataataaagg tggaaaagga ataagtattg
     5161 cagatgtgat gactgcaggt actcatacta tttcaagaaa gataacagat ggagtaattg
     5221 agggtttaaa ttatcctaat catgaagcca ttaattttta tgaaaattat aaagaagata
     5281 ttagattatt tgctgaaatg ggatataagt gttttaggac aagtattgct tggactagaa
     5341 tttttccaaa gggcgatgaa tcaactccaa atgaagatgg attgaaattt tatgatgatt
     5401 tatttgatga attattaaaa tacaatatag agccagtaat aactttaagt cattttgaaa
     5461 tgccttatca tttagtaaaa aactatggtg gatggagaaa tagaaaatta atagatttct
     5521 ttgtaaactt ctgtgaagtg gtaatgaata gatacaagga taaagttaag tactggatga
     5581 ctttcaatga aataaataat caaagtataa ctacaaatcc tatttatgca tttactaact
     5641 cgggaataat ctatgaagag caggaagaca aagaagaagt tatgtatcaa gcagttcatt
     5701 atgaatttgt agcaagtgca aaggttgtga agataggtca tgaaataaac cctgagttta
     5761 aaattggatg tatggtggca gctatgccaa gttatcctta ttcttgcaat ccagaggata
     5821 tgattaaatt tgtagaatct aatagagaac aacttatgtt tactgatgta catgtaagag
     5881 gtcattatcc aagacataca ctaaaattat gggaaagaaa aaattataat ttagatatta
     5941 cagaggaaga taaaaaaatc ctaaaagaag gaatagttga ttttattgga tgtagttatt
     6001 atttaactac tgtagtaaca gctgataaaa ctatgaaaac aacaggtaat gactcggcag
     6061 gaaaggctga tgtagttgaa aatccatact taaaaatttc tgattgggga tggaatatag
     6121 accctgtagg tctaaggttt taccttaatc aactatatga taagtatgaa cttcctatat
     6181 tcattgttga aaatggattt ggagcagaag atgtattaaa atcagataat actgtagatg
     6241 atgattatag aatagagtat ttggctagtc atataaggga aatgaaaaat gccattgaaa
     6301 ttgatggtgt tgatgttata gggtatactg tttggggatg tatagatcca gtatcattta
     6361 caacaggaga gatgaaaaaa agatatggat ttatatatgt agataaaaat aatgatggaa
     6421 gtgggactct taaaagatat aaaaagaaat cttttgattg gtataaaaat gtaataaaat
     6481 ttaatggaga aattttatag gtagataaat tttaatattt ataagattat gttaaggaaa
     6541 ccattaaaaa ttagattaaa atcgtgggta tttaaatcca ctaaaagata ttgactattt
     6601 agtcaatatc tttttttatt aaaaagtaaa tataaagagg taaggttaaa aattgggata
     6661 tatatgattt atatagtatg atttaattag aaggagctat attagtattc atttgtatag
     6721 ttggagaata aatgtcagtc ttaccttacg atttttataa tagtcctatt taatttctat
     6781 tgtaactaat atgcaagaat ttaagataga agtatctatg acttatggtg tattaataat
     6841 tggtatctgc tatctagtat ctttttaatt tttttgattc caatatagtg ctaactacga
     6901 tacgaatatc tttaaattta tagctaaact atctaattgt ttattggaaa gagttaagaa
     6961 ggctaaagca taaaacactt aaaaagagaa gatgtatatg agaaatataa ttaactatga
     7021 tgcagacttc taaaaattat ttagtgaaaa ggaacttaga gtgtataata aaagttcctt
     7081 ttcactaagg aaaacgattg ttattttctg atcttcatta ccctgatatt atttaaatat
     7141 aaacaacaac aaaattaaca agaagcaaat tcaacctaaa atttaaaata tcgggaggta
     7201 caatatgtta ataaatatga aggaaatgct aaaagtggca caagaaaatc aatttgctgt
     7261 accagcattt aatataggaa gtgggcaaat acttaaagca gtagtacaga gtgctaacga
     7321 aaaaaatgca ccagtaatac ttgcaataca cccaaatgag ctaagttttc taggagatag
     7381 ctttgtagct agttgcatag aagaagcaaa taagagtaaa gtacctatgg taatacactt
     7441 agatcatggg gaaaataaag aacaaatatt aagggcaata agatgtggat ttacatcagt
     7501 aatgattgat ggctcacatt taccatatga agagaatgta gctatatcta gggaaatagt
     7561 agaaatagca aaaggattaa atgtgtccgt agaaggagaa cttggaacaa taggaacaac
     7621 aggaacatca agtgaaggtg gtactgatga aataatatat acagattcaa aattagctaa
     7681 ggattttgtt gaaaaaacag gagtagaaac actagctatt gcaattggta cagcacatgg
     7741 tatatatcca aaaggtttta aaccagagct taaactagat ttattaaaag aaataagaga
     7801 agtagtagat atacctttag ttcttcatgg tggttcatca aatccagatg aagaaatagc
     7861 acaagcagtt aaactaggag tttgtaaaat aaatatttcg agtgatgtta agtcggcata
     7921 ttataagaag tgcagagaac tattagaaca aaacccaagc ttatatgagc cagatactat
     7981 atatccacca tgtataaaat ctgcaagaga agttatagag tttaaaatga atctattcaa
     8041 tgctatagat aagttaaagt gcttttataa aaataaaaat taattatgag gtaacaaatt
     8101 aaaaggaggg gagaatttat gataggtaaa atactacgaa gcgattgtat tgtactagat
     8161 aaacaattac aaacaaaaaa agatgtaatt aattatatgg caaatcattt gtaccatgga
     8221 aattatataa ataataaaga aaagtttata gctgatatta ataaacgcga aaaagaatca
     8281 tcaactaata tgggtaattt aatagctata cctcatgcta agtcaaatgt agtaaatcaa
     8341 cctgtaatga tgtatttaag aacagataga gagattacag ataatgatgg tcaaaaactt
     8401 aggtcatttt ttatgatagc agttccagaa tcaggttcag atgaacatct taagattata
     8461 tctaaactag ctacatatct aatggaagaa aattttctta agcatctact aagtgcagaa
     8521 actccatacg aaatattaag tatatttaat aataaagctg cagaatcagg agattttagt
     8581 aataatcaaa ataaaggtct tatagttggg ataacaggat gtccaacagg tatagctcat
     8641 acttttatgg caaaaaaagc attagaggaa gcaggtcaag aacttggata tgaagttaaa
     8701 atagaaactc atggagctat aggtgtagaa aataagttga ctaaagaaga tataaaaaga
     8761 gctgaatacg taataatagc ttgtgataaa gaagttcaac tgagtagatt tataggaaag
     8821 aaagtgctac aaaagaaagt agtagatgct aagaatgttt cattagctaa aaatttaatt
     8881 ataaacgctg aaaatggaat ggctaaagaa attaaaccag gtggaaagac tttagaagat
     8941 tcaaaagaaa tgcttcaagg gtcagagaaa aagggtgttt ataagcactt aatgagtggt
     9001 gtatctgaaa tgattccatt tgtagtgata ggtggaattg gtatagccat agcttttatg
     9061 tttggtatat ttgcatcaga cccaactcat gaaacataca accctatagc tggattcttt
     9121 ggacaacttg gaggcgattc agcatttaag ttatttatac cgatacttgc tggttttata
     9181 gctaaatcaa tagcaggaag acaaggattt gctcctgcta tgatagctgg ttttatggca
     9241 gttattggag gttcaggttt tataggtggt atggtagctg gttttgcaac aggatatata
     9301 gctttaggag taatgaagat aacagaaaat ttaccagatg tattaaaagg agtaaatgct
     9361 gtattgatat gtccactttt gattgcattt acgagtggag ctataatgtt ctttgtagtt
     9421 aatacgccag catcatggtt aaatgaagct ttacaatctt ggttacaaag tatgtctgga
     9481 actaataaag tattattagg tgcaatatta gcagggatga tggcatcaga tatgggagga
     9541 cctattaata aaacagcttc agcttttgga ttggctatgt tttcaagtaa tatatttgaa
     9601 ccatcagcag cattaatggt aggaggaatg gtacctccat tagcaatatc attagctatg
     9661 ttaatattca aaaataagtt tactaaagaa gaaagaaagt catctctacc aactgctata
     9721 atgggggcat ctttcataac agaaggcgca ataccgtttg cagctgcaga cccattaaga
     9781 atgattccag caaatataat tggttcttgt ataggtgggg caatatgtat gagtttagat
     9841 ataactttaa tggcaccaca tgggggaata tttgtaatac catttgcatg tagtgcacca
     9901 gttgcatata tagcttgtat attgattggt acagtaataa cagcattgat tataggggta
     9961 acaaagccta ctataaggag tgaaaatagt gaagttgaat tacttggtgc ttaaattata
    10021 aataatagta aaaataatta atggaataac aacaagtata tagaataata ataaggatat
    10081 ttagaatcag ttaactactt ctaaatatcc ttaattttta ttttgaaatt atattatcta
    10141 ttatatcaat ttagtaaggt gtatcataaa ttcttttatg atacagaagt atcttagtaa
    10201 ttttacatag ttagtaaata tgttaaaata gtacttaata taaacataga aatatataaa
    10261 cataggtagg gagggctaag tatgcttgtg tcgaggcaaa ttgaatttct taaattgata
    10321 ctaaacgaaa ataaatatag acctataaaa tactttaaag ataaattaaa tgtatctgat
    10381 aaaactttac aaaaagattt gaagatgatt gagaaatatt tagaaacttt taatataaaa
    10441 attgatataa aaagaggcta tggaatatta atagaagatt tagcaaagaa gaatatagac
    10501 ttaattaata gtttaaatat acaatcgaag gaaaataaat ctttatcagt agagcagaga
    10561 agaatggaga ttttaaagta tttattacta aattcaaata atataacttc aataaatcag
    10621 ttagcagata aatattatgt aagtaaaact tctatagtaa atgattttaa atatatagag
    10681 gcatggataa aagaatacaa tttaaaactt aataaaactt tagaaggaac taagattata
    10741 ggtaaagaag tggatataag gaaatcgatt gccaaaatga tggatgattt attagatgaa
    10801 aattatgaac aacatgatat atctgagtta acaagattag attctgctac atttagtgca
    10861 ttgataaatt tatttgatat tgattctatt atatttgtag aaactataat tacagaatta
    10921 gaatacaatt taggatatac tataaatcag ccctactata taaatttaat tacccatata
    10981 cttatatgtt taaagagaat cgaagaaggt aatcaaatag aatctcagga agaaagagaa
    11041 atttctgtag ataatttgga cgagttagta tataaaaatg tcagtacact tatagataaa
    11101 atagaaaata gatacagagt aaaaataacg aaagatgaaa ttatgtacat atatattttt
    11161 ttggtatcat ctggatttag tagcgaaaat aatagtagtt acaatgatga atcagataga
    11221 ttaagtgaaa gtgaaaaagt ttcatctata atgatagaga atatgtcacg atttttaaat
    11281 ataaatctca aaaatgatga cttactacag aaaagtctag catctcatgt aaggcctatg
    11341 ttaaacagat taagatatga tatccaaata aaaaacccgt tgttaggaga gatacaagag
    11401 cgattttcag atgtgctggg attatgtatg atgactataa atattatgac agagtatgat
    11461 aatctgaaga atattagtat agatgaagtt tcgtatcttg ccacatattt tcaagcggca
    11521 atagaaagaa atatgagtag taaaagagta atagtagttt gtcatacagg atatggaaca
    11581 tctcagctcc ttgcagccag attaaaaaga gaatttcctg aatggactat agttgatata
    11641 gttcctatgc atcagttgag taagcgaaat ttagatgatg tagactttgt aatatctact
    11701 gtaaacttag atttgaaaga taaattacat atagttgtat cagtactatt aatggaaaat
    11761 gatattaata atataaaaaa tgctttactt tctaaaccta aaaaaagtat gaacttagat
    11821 acaaacttat taggaatgta tttagaagat aatatatatt ttaattttga tgtagctcag
    11881 atggaaagtt taataggtgt gaatttaggg agtaaatatg aatctatttc attaggaaaa
    11941 gatttaaata tatatataca taagcaaagt aaattaaata aagggataat gaatatcaat
    12001 aatgttacta gaacgattga tatttattta gaaattagta atcaaagttt tttaaagaat
    12061 attttaatgg aaatatcaaa tttatatagg caaaagaact atataaacta tataatagat
    12121 tgcaagagca aagaggatat taaaatatta tttaagaata atctattgga gaaaacaaat
    12181 ggaaattaga gaaatattaa cagaagaaag cattatttta gatttgaaat caactacaaa
    12241 agaaggcata atacaggaat tagtagataa attatacgat acaggaagta taactttaaa
    12301 aagtaagttt ataaaggcat taaaacatag agaaaaaata ggctctacta gcataggtta
    12361 tcaaatggcc atgccacatg gaaaaacaaa atatgtaaag aaggcatcca tagtaatagg
    12421 taaatctaaa aaaggtgtag attggccaag tatagatggc ttacctgtaa aggtaataat
    12481 tatgtttgct atgccacaat ctggaggcaa tgaagatatg atattaatat ctaaaatagc
    12541 ttacatttta ggtggtaaaa atataggtga aagactttta aatgcaaata caaaaaaaga
    12601 aatattagat atattttatg aagtgtaggt attgtataaa ttataaattt gaggttttta
    12661 aaataaaatg tgtattcttt taaatagtat aaattaattt ttagacacta gagaggagag
    12721 gatatatatg gcaatatatt tagaaatgcc taaattaata catgaatttc cttttcgtag
    12781 tctatcaaat gaaggagaag tattaacaac accacactgg cataaggaaa tagaaatatt
    12841 acttataaca gaaggtgtag taaatctatt tataaatgac aagcctatgc aattaaaaaa
    12901 aggcgagata gtgataataa aaggaggaga tattcattat atactgccat caccgggaag
    12961 tgaaagatta gtatttcaat ttgatatatc tttttttaat gatttaattt tattaaatga
    13021 ggaaaaagaa agcttaatta atttattcag tagtataaaa aaatgtagta gagattggtc
    13081 agcaaaaata agaaagtcag ttttcgatat attgatagat atctacaatg aagacctata
    13141 caaaatagaa ggatatagtt atgcaataaa aggtaaaatg tataatttaa ttcctatatt
    13201 atatagacag attcctagag aaattgaaga aaatacagta gaatatgaaa taaactctaa
    13261 agagatatta gagagattga acaatatatt caaatatgta gaaaaaaatt ataaacaacc
    13321 tataaaatta gaagatgtgt cttatgaagt aggatttagt gtatattatt ttactaaatt
    13381 tttcaaaaaa aatacaggaa aaacatttat aactttttta aatgaatata gattagaaaa
    13441 agcaaagtgg atattactta ataacaatat atccattgta gatttggttg aagaagttgg
    13501 ttttggaagt acaaaaactt tttacagagt atttaaagaa aaaattggag tctctccatt
    13561 agaatttaaa aaaagatata atagcttgga aaaaaaaggg agtgtctcaa aatgaactta
    13621 gttcatgagg cactttcttt tatatgaaat caaatatatt ttcagtattt caacaatgaa
    13681 aattccattc atttataaag tctaaatttt agttctcaat acaacctcta tttcgaaata
    13741 aatcctttta tatataaata tacagcaata tatgagaata agataacaat aatgaggata
    13801 taaaaatgta tttgctatat atataattat atacatagat atctaatatt gatatttaat
    13861 atgaaagtat tgaaaataga caatattaat tatagtgagt aaaaaatata attggatttt
    13921 taaattgaat tatttaaaag gtatagtatg aaaaaaatct tataactaaa tatgagatag
    13981 aaattataaa actttatatt gtgaaagagg tagatgcatg aaattaggga aagatttttt
    14041 atggggaggg gcaatttcag ccaatcaaag tgaaggattt tatttagatg gaggaaaagg
    14101 tttatctcag tttgataaac tcccattaaa tgataagaga ttaaaagatg tatgtttaga
    14161 tgaggataat attttaaatg aaaataatca atactatcca agtcatatag ggattaaatt
    14221 ttgtgaaaat tacaaagaag atatagcaat gttagcagaa ataggtttta aatgttttag
    14281 attttctata tcttggtcaa gaatattccc aacaggagaa gaaagtgaac caaatgaaaa
    14341 gggattacaa ctttatgata atataataaa agaattaaaa aaatataata tagagccatt
    14401 aataacgata agccactttg atatacctta ttctctagtt gaaaaatatt ctgggtgggc
    14461 tgatagaaga gtggttaatt tatatgtaaa atatgctgaa attttgatga aaagatataa
    14521 agatgatgtc aaatactgga ttccttttaa cgaaatgaat atgataatgc atattccata
    14581 tataggtgct gggttaactt ttatagctga tgaaaatcaa cttcagaaaa aatatcaagc
    14641 agcacaccat caattattag ctaatgcaaa aactatagaa ataggaaggt atataaataa
    14701 agaatttaag tttgggtgta tgttagctgc tggaaaaaca tatccataca catgtaaacc
    14761 agaagatgta tttgcaactt tagagcatga aaggcataat ttgttttttt ctgatgttca
    14821 agttaggggt gtgtatccaa gctttatgaa ttattattta aaatcaaatc aaataaaatt
    14881 aataataaaa gaggaagatt tatcaacact taaggataat actgtagatt ttgtatcttt
    14941 tagctattat tctagtgctt gtagttcagc tagagctgaa ggtttagaaa aatcaaaggc
    15001 aaacggacca gaaaccataa aaaatccata tcttccaaaa tcaaatagtg tatggcaaaa
    15061 cgaccctgta gggttaagaa taactatgaa tcagttatat gaaaggtatc agttaccttt
    15121 atttatagta gaaaatggac tgggtactca agatattgta aatgaagatg gaaaaataat
    15181 tgatgattat cgtatagatt acatgaaaga acatattaaa aatatgatta ttggagtaaa
    15241 tgaagatgga atagagctta taggatatct tatgtgggga tgtatagatg taaccagtgt
    15301 aagtgaagga aagatgacaa aacgatatgg cataattcat gttgattctg atgactatgg
    15361 aagaggctca tttaaaagaa ctaaaaaaca aagtgctttt tggtataaaa aagtaataga
    15421 aacagatgga gaaattttat ttaatgacat ggaaactcat gcataattca ttttaagaaa
    15481 ggagtgttat tatgagttta atatttacta ctaaggacca acttatagag caagggttta
    15541 gtaaggatac aataaaatcc aatgaaacgc tgtttacact agctaatgga catttaggag
    15601 ttagagggaa tattgaagag tctgatttta ataatgagta tgtagataat atgggtacat
    15661 atgtaaatgg attttatgaa gaatctccaa ttacatatgg agaaagcgct tatggctatg
    15721 caaaacaaaa tcagactatc tgtaagttac ctaatgctca tatagtaaat ttctctattg
    15781 aaggagattg ctttgattta tcaaaaggta ttacaagtga acattctagg atactagatt
    15841 taaatgaagg gattcttaaa cgttcattta tatgggaaaa ctctcgtggt agaaaagtta
    15901 aagtatctat agaaagatta gtatcacaag atatagaaga attaatgatg atttcatata
    15961 caataacacc attgaatttt aatggaaaaa taaaatttaa aaataaaatg gaaaatagta
    16021 tggagaagtt taattgtgaa aaagtagagg acccaagagt ggcatctata aataagaagc
    16081 aatttaaaat taatgtaaaa aaatataaca ataagtattt tatgaattta gttacagaaa
    16141 gaagtagatt agggttatgg tgtgggtttg attcatatat tacttgtgga aatattacaa
    16201 atgagaccta taatgtttca gatgaatgta ttgagcgaga aatagaagtc tatgccaaaa
    16261 aagatgaaag gttaaattta gaaattgttg taggctatag tagagtatat tctgatttaa
    16321 atctaaatga agaacgttta aaatcattag aatgtctgga gtcgttaaaa tgtttagaat
    16381 cagaagcaca tttaaaatca ttagaattgg ttttaagaga agcatgtaat attggatttg
    16441 ataaagtcaa aaatattcag agaaagaaaa tgaatgagtt ttggacaacc tctgatgtag
    16501 agattgaagg cgataaaact cttcaactgg ggataaaaac caatttattt catatttatc
    16561 aatcagtagg aagagatgga aagactaata tatcagcaaa aggtcttaca ggtgatggct
    16621 atgaggggca ttatttctgg gatacagaaa tgtatatatt accatttttt atatatactc
    16681 aaccatccat tgccagagct ttattagatt atagatactc aatcttagat gcatcaagag
    16741 aaagagctag agaacttgga ataaataaag gttgcttata ttcatggaga actataaatg
    16801 gtaatgaatg cagtgcatat tatccagcag gaacagcaca gtttcatata aatgcagata
    16861 tagcttatgg tattagaacg tattttgaag caactaatga tgaagaattt atgatgcaaa
    16921 atggcttaga aattcttata gaaacagcaa gattttgggt tgaatttgga gattatatag
    16981 aatcaaaaaa taataaattc tgtataaatg gagtaacagg accagatgaa tatacagcaa
    17041 tagtaaacaa taattactac actaatttaa tggctaagta taatttaata tatgcagtac
    17101 agatggtaga taaatttaag cataatttat tttcaaatga agtatttaga aaagttaaat
    17161 tacaagaata tgaagtgaaa aactggataa atgccgctca aaatatgtat ttaccatatg
    17221 atgaagagaa gaaaataagc aaacaagacg attcattttt agaaaaatca gtatgggatt
    17281 ttaaaaatac accaaaagaa aaatatccat tacttcttca ttatcatcca ttaacaatat
    17341 atagatatca agtaaataaa caagcagata ctgtactttc agcgttgctt ttccctgatg
    17401 agtttagctt agaacaaaag aagagagatt ttgaatacta tgaaaaaata actactcatg
    17461 attcatcttt gtcaaggtca atatttggaa tgatggcaag tgaaattgga aatcatgaaa
    17521 aagcttataa ctattttatg gacacagcat taatggatat taataaccta caaaaaaata
    17581 caagtgatgg aatacatgct gctaatatgg gtggaacatg gatgagttta gtatatggat
    17641 ttgcaggaat gaaaataaaa aatgataaat taagttttga accaaggata cctaaacact
    17701 ggaaaaatat taaatttaat atattattta gagataattt agtttctgta aatatagaag
    17761 aatataaatc ttattataag ttaatcaaag gtagaaatat aaccatatta catgataata
    17821 aagaaataaa attatcaaag aacataatag aagttaataa ttgttttaaa gggagtaatt
    17881 aatatgaaag cagtcttatt tgatcttgat ggagttataa cagatactgc taagtatcat
    17941 tttgaagctt ggcatgagat agcaaaatcg ctagatatag aaatagatga aacttttaat
    18001 gaaaaattaa aaggcataag cagggaagaa tcattagata aaatattgtt atctgctaat
    18061 aaagtagata gttatactaa agaggaaaag ttaaaggtgt gtgaagaaaa aaataacatt
    18121 tatataaagt taataaactc attaacatat aaagatatat taccagggat aaatgagctt
    18181 ataaaagaac ttaaaaaaaa taatgtgaaa ttgggaatag catctgctag taagaatgca
    18241 cctaggatat tagaatcttt gggaataaaa gatgaatttg attgtatagt aaatccatct
    18301 ttattaaaaa ggggaaaacc atatcctgat atttttattg aagggagcaa gattctaaat
    18361 ttaaaacaat atgattgtgt aggaatagaa gattcttatt caggtattaa agctataaat
    18421 gctgctaata tgacatcaat tggtgtgggg aaaaaagaag tactaggaaa atgtgaccat
    18481 attgtagaag atactagctt attaaattac aatacactat tacaagcttg gagtaaaaag
    18541 attaatttgg attaaaatta tattaaaaat tattttaaaa gagaggataa ggtatgaaga
    18601 ataaatatga agaagtagct caattgataa ttgatggact tggaggaaag gataatataa
    18661 ttgacttaac tcattgtatg acacgattaa ggttcatctt aaaagatgaa aagaaagtca
    18721 atgcagataa attaaaatct atagataagg tagttggagt aaactcaact tcaactcaat
    18781 atcaggtcat aataggtaat gaggtaggtg ttgtatttaa tgcaataata aataagggga
    18841 taaataccac aggagatatt aaaagcgata taaaaaataa aaataaaaaa aatagtattt
    18901 taaataatat aatagataca ataactggtt gtatgacacc tatgatacca gcccttacag
    18961 catctgggat gataaaagtt atattatctc tttgcaccac ttttaattgg ctatcatcaa
    19021 attcaagtac atatagagta ttagatataa taggagatgt agcattttac tttatgccta
    19081 taatacttgc aataaatgca gctaaaaaat ttaatgttaa tacatcaata gcagttatag
    19141 tagtaggtgt gtttttacat ccaaatttct ctgcatgggt atcaagtggg gaccctatat
    19201 catttatagg agtaccaatt caagatgtta tatatgcagc atctgttatc cctgcacttt
    19261 taacagtatg gatgatgtca tatatagaaa aattcattga taaattaaca cctagcatgt
    19321 taaaaacaat tttaaatcca actttagtat tattaataag tgcgccaata gcattaatag
    19381 taattggacc aataggaaat ttcttaggag agggattagc tagtataata aatttactac
    19441 aaggaaggtt aggatttata atggtttgtt tattagcagc tgcaatgcca tttatcgtta
    19501 tgacagggat gcatcatgca ttgactccta tattcatatc agcatttgca actacaggac
    19561 aagaatcgct aatattaata tctcaagttt gtgctaattt agcgcaaggt ggcgcaacat
    19621 tagctgtagc attaagaagc aaagatagta agatgaaaca gttagcatca gctgcatgga
    19681 tatcagctat catgggtata actgaaccag ctctttatgg agttacattg aaacttaaaa
    19741 aacctgctat gttagcatct ataggagcag gaatcgcagg gttatttgca ggaattactc
    19801 atgtgacttt atatgttcca caaaatagta taatggcagt acttggatta tcaggggaaa
    19861 aggggatttc aaatatagta aatggactta tagttatatt tatagcattg gttgctccat
    19921 ttattatgac atatgttttt ggagttgaaa aaaatgttaa ataaagtaca gataatgtag
    19981 tagaggaagt ataatattaa ctatttacat taatagaatt tttattatta ttgactataa
    20041 cttgttttgt atttatattg atgcaaagaa ataagttaat attaataaga ataattatta
    20101 gaactgacaa aaagcaacat aaaagattga tgaagtatat ggaaataaaa agttgacaaa
    20161 atatgtctga tgttttatca tattaattgg aattaggtag taattgttta agtacaagct
    20221 aagcttattc attaataata gcagtatcct aggaaggagt atgcccatta ttatggataa
    20281 gcttttttta tgcttaaaag gaggataatc atgataatta ataagatatt aaacaataat
    20341 gttgtaatca cattagatga taatgatgaa gaagttatcg ttatgggtaa aggaattggt
    20401 tatcaaaaat caaaaggcaa tctaatagat aaaactaaag taaataaagt atttagaata
    20461 tcaaataaag aaatatcaaa caaactacaa gaattactca ataatattcc tatagaacac
    20521 atgaaattat caagtgaaat tatagaatac gcacaaataa agttaaacaa gaagctaaat
    20581 gaaagtattt acatatcctt aagtgaccat acatattctg caattcaaag gatgaaagaa
    20641 ggaataaatg taaaaaatgc aatcctttgg gaaattaaaa gattttataa agaagagttt
    20701 gaaattggaa tgaaagcact agatattatt gaaaacaaaa caggtataaa attaccagaa
    20761 gatgaggctg gatttatagc ctttcatata gtgaatgctc agttaagtga aggtcatact
    20821 ttggcatctg atattacgaa gttaatacaa gaagtactta gcatagttag gtatcatttt
    20881 aggatagaat ttcatgaaga atcagtgttt tattatagat ttataatgca tttaaagttt
    20941 tttgcgcaaa gattgctttt agatagtgca catgaaggtg agacagacaa agaattacta
    21001 agcattatta aatctaaata taataaagag tttgaatgtg tagttaaaat taaaaatttc
    21061 attaaaaaac aatataacta catattaaca gatgatgagc ttatatattt aacaatacat
    21121 ttagctaaag tagttaaaga ctcaaatatg taagtgaaat aatttttcag tagtatatta
    21181 agaatgattg aaaggagtga tactaacaaa attatactta tggttggatg gtaacattga
    21241 gttggccaaa ccttcaaatt tcaaaaaatt aatttaaacg aaatatggag gagaaaaatg
    21301 ggaaaataca aacaattagc acaagagata gtaaacaatg ttggtggaaa agaaaatatt
    21361 agtgggttag tacactgtat tacaagatta cgttttactt taaaagatga aagtatagca
    21421 aatgacaatg tattaaaaaa catggaaggt attgttactg taatgaaaag tggaggacaa
    21481 tatcaagtag ttataggaaa tcatgttgaa gctgtctata aagatgtagt tgaaataatt
    21541 ggtttagatg attcaagtac aagttcagaa actaaaaaat caggtaatat actagataaa
    21601 ggtatagata taatatcagg aatttttcag ccagtgttag gaataatggc agcttgtggt
    21661 atgttgaaag gatttaatgc attatttgta gcaatgggat tatatagtga tgtatctggt
    21721 ggttatatgg taataaatgc agcaggagat gcattattta cattccttcc tttgttctta
    21781 ggatatactt cagctaagaa gtttggatta aaaccaatgt tgggattagc actaggagct
    21841 gcagtatgtt atcctgctat acaaggtagc agtatatcag caggagcaga tgtgatgtac
    21901 actttattta aaggaacaat gtttgcatca ccagtatata ttgatttctt tggactacca
    21961 attgtatcaa ttgattatac tggaacagtc gtaccaatta tatttatagt gtattttgct
    22021 tctaggtgtg aaaaattatt taataagtgt gttccaaatt tagttaagtt tttctttgtg
    22081 ccaatgctta cattattaat aacagtgcct gttgcactta tagttatagg ccctatagca
    22141 acatttggtt ctacacttat ttcacaaatt gtaatttcaa taagagattt tagtccacta
    22201 ttggcaggtg ctatagtagg atttacttgg caaattcttg ttatttttgg tatgcactgg
    22261 ggatttattc ctgtatatat aaacaatgtt atgactttag gatatgataa tgttatgatg
    22321 ccattctttg cctgtacatt tgcaagttcg gcagttgtgt tggcaatatt tttcaagact
    22381 aaagataaaa aactaaaaga gatggcaata ccaaacttta tatctggtat atttggagtt
    22441 acagagccag caatttatgg aatattattg cctttaaaga aaccatttat aataagttgt
    22501 attgctagtg gtattggagg cgctttctat ggattcttta atcttagaaa atttataact
    22561 ggaggaatgg gaatatttga acttccagca atgattgaac cagatggggg aatgggtaac
    22621 ttaatagtag ctctttctgg tatagctata tcaatggtcg tagcttttgt attaactatg
    22681 attttatata aagatgagaa agtagaagag tctaaaaaag taagaaataa gggtaaagaa
    22741 gaaataaaag aagtcaagtc tactaaatta gaaagagaaa tagtaacaag tcctataaaa
    22801 ggtgaagtat taaaattaag tgatatagag gatgcagcat ttgcatctgg tgtactaggt
    22861 caaggggtgg caataatacc tagtgatgga aaagtagttg ctccagtaga tggggtagtt
    22921 acaaccttat ttcctagtct acatgctata gggattcttt ctgatacagg tgttgaagtg
    22981 cttattcata ttggattaaa tactattcaa ttagagggaa gaggttttga ggcatgtata
    23041 aaacaaggtg atagaattac aaaaggtcaa actatattaa actttgatgt ttatgcaata
    23101 aaagagttgg ggtatagtac tgtaactcca attgttatta caaattcatc acaattttta
    23161 gatgtagtag aaacagaaag taaaaatatt gaattagaag acaatctaat tacagtctta
    23221 ttttagtaaa gattgaggta ttagcataat ctagtgcttt ggttataatt ttaggaggct
    23281 ttgactatga gttttaagaa tgatttttta tggggaggag ctactgcggc caatcaatgt
    23341 gaaggtggat acaatgaaga cgaaagagga ttggcaaatg tagatgtatg tccaacagga
    23401 aaagatagaa cagcagttat tacagggaaa ctaaaaatgt ttgattttga tgatgagcat
    23461 tattatccag ctaaaactgg tattgatatg tatcataatt ataaagaaga tataaagtta
    23521 tttgctgaaa tgggatttaa agtatataga atgagcattg catggagtcg aatatttcca
    23581 aaaggtgatg aagaaacacc aaatgaaaag ggacttcaat tttatgaaaa tatatttaag
    23641 gagtgtaaaa aatataaaat agagccttta gtcactatta cacactttga ttgtccaatg
    23701 catttagtta aaaagtatgg tgcatggcgt aatcgaaaaa tgataggttt ctatgagaaa
    23761 ttatgcaatg ttatctttag aagatataaa ggattagtga agtactggct aactttcaat
    23821 gaaataaata tgattttaca tgctccattt atgggtgctg gtatttgctt tgaagaaggt
    23881 gaagatgttg aaaagataaa atatcaagct gcccatcatg agcttgtagc tagtgcaatt
    23941 gcaactaaaa tagcacatga agttgattca aataacttaa ttggatgtat gtttgcagct
    24001 ggaagtgtat atccttatag ttgtaatcct aatgatgtat gggaagctac aaagttagat
    24061 agagaaaatt acttctttgt ggatgtacaa tctaaaggta aatatcctaa ctatgcgtta
    24121 aagtatatgg agcaaaaagg tattacacca gaaatggaac ctggtgatat tgaattattg
    24181 aataaatata cagtagattt tatttcattt tcatattaca atagccgttg tgttagaacc
    24241 gatgaaaatg cagatgatat ggctgaagga aacatattta catctgctaa aaatccatat
    24301 ctttcataca gtcaatgggg atggccaatt gacccattag gtttgagaat tacactaaat
    24361 catgtatatg atagatatga aaagccacta tttattgtag aaaatggatt aggtgctaaa
    24421 gatatagctg atgaaaatgg ttatgtagaa gatgattaca gaattgatta tctaagagaa
    24481 catataaaag ctatgcatga tgcagtttct atagatgggg tcgatttatt aggttatact
    24541 acatgggcac ctattgattt agtaagtgct ggtacaggtg aaatggaaaa gcgttatgga
    24601 tttatatatg tagatagaga caatagtggt aatggaagtc taagaagaat gaaaaagaaa
    24661 agttttgaat ggtataagaa agtaattgct tcaaatggtg aagatttata ttagacaaga
    24721 aatctatgtt aaataagaaa tctatattag acaagaaatc tatgttaaat aagaactttg
    24781 tattaaataa gaagagtata aaaattaata ataagtataa tttttaactt ttttaactat
    24841 agaaaatcaa tatagaatta ttttacattg tattgatgca atagtatgat tcacaaataa
    24901 aattttagaa aataaaattg ttaagaagta tgggaagtaa gtgcaattta ctttgtaata
    24961 aaagatgaaa aaggcaagct taggttttaa gcttgtcttt tttattatgt ataaactatg
    25021 atattttaaa attctatgaa aaatttattt aatagagaaa ttaaaaattt aatggtaatc
    25081 aaattcttta ccaatgaata taaaaaatgt ctacgtgtta taatagttta aactaataaa
    25141 cgaaaggtag atgaatgaat atgaaatacc aacatataat agaagttgac aaagaacttt
    25201 gcattggatg tgggctttgt aaaaatgatt gtccagtaaa caatataatt atagaaaata
    25261 aaaagtcagt aattaaaaaa caagattgtc taatgtgtgg acattgtgca gcaatatgtc
    25321 ccacaaaagc tattaccttg acaggatttg atgaacctcc tatagaactt acaaataagc
    25381 caaagctaga ttcagatgaa ttactaatgg caattaaatc tagaagaagt atacgtaaat
    25441 ttaaagataa agaagtttct tcagaaatta taaagcaaat tattgaggca ggtaggtata
    25501 cccctagtgc taaaaattca caagatgtat catatattgt tttagacaat aaaaagtcaa
    25561 tttatgaaaa cgaagcagtg aaatttttta gaaaaataaa acctattgca aatatagcta
    25621 ttaaatattc aaaagaagtt gagattgacg ataacttttt ctttaagcat gctcctattg
    25681 caataatgat aattacaaaa gataagatta gtggttcact tgcagcatca aatatggcat
    25741 taatggcaga gtcttatggt ctaggtgttt tatttagtgg atatttttca gatgtagcaa
    25801 ataattcgcc aaaattaaaa aagcttttag gtctaaaacg tagtaatcat gttcttacaa
    25861 cattagtaat tggataccca gatgttaaat atagacgtac tgcacagaaa gaagtagcaa
    25921 ctgttagata cttataagag agggtggatt ttatggaaaa agaatgtcaa caaagaatgc
    25981 aagaaataac gtctaaattt aaagaatgtc gcaaagctat ctctgctatg ggtgatgaga
    26041 ctagacaatt gattttaatt gctcttttag agagtgattt taatggtata cgagtgggag
    26101 aaatcacaaa aaaaacacat ctttctcgtc ctgctgtatc tcatcatctt aagatattaa
    26161 aagaagcaga gattgttaat ttgcgtagag aaggaacgaa aaattattat tatcttgatt
    26221 caaaaaaatc acaatggaag tcactaacag agctaataaa tcttatattt gttggaatac
    26281 aacatattag tgaaaatgat ataagaaaag gtgattaaat tatacttgat ttaatacaaa
    26341 aagattgatt taggaactaa aaaattcact ttgagacact atcttttgaa ctatacccat
    26401 tttaggagac ggttaaaata tgtaaaactg tataaaacaa tgggtatagt tcattttata
    26461 atggtttaaa tattaagaat atattattct aaatagtatc tttctctgtt ttgagtttta
    26521 tttttatact caatagcttc agtggggcaa ccacaaatac atgccataca atgagtacag
    26581 ttatttttcc aaactggttt tttgtttttt aaattaatat tatttaaagg acatagctct
    26641 acacattttc cacagccaat gcatttatca gtataatgaa atcctttggc actaataatt
    26701 gtcttataaa aaactgtatt tattatacca cttttaattg tacctcctaa gccactagga
    26761 gtaatagttt caaattcatt ttcattgcgt atatcagaaa taatcctata tatttgttta
    26821 tctgcttctt taatcatttg ttttgatgtt tctttgtctg ttgtagaaaa taaagctata
    26881 taattctctg gcattttaat ttctgccata ccttttaatt gccattcctt gtatttacat
    26941 agtttttgaa tatagtttat ggattttgct gtatctccac cacaagtcat tacaaagtaa
    27001 actctgttgc ttcctagaaa ttttgtttct tttataaaat ccgtaactac tattggcaat
    27061 ctccatgcat aagtaggaca tacaaatatg aatggtttat ctgctgatat taattcatct
    27121 gttttttcct cttttataag ttgatttagt gatatcagtt catcatttaa ttcttgtgca
    27181 attttacgag ccacatatcg gctattacca gttccgctaa aatataaaat cataataata
    27241 tctccctaac tattttttat ttattatagt aatttattga tatattctat tcaaatgtat
    27301 gtaaaattta gtagttaaga aaattataac acattagtaa tttttatact tattggtaaa
    27361 gaatttgatt accattaaat ttagcaacaa gacatcaact ggacttgtat atgagaaggg
    27421 ataataattt gcttatgaaa gattataaat ataaaggtta ttttaaaggt gtagaaatat
    27481 ttgataatgt aaatgacctt aacttaaata ctttaacaac agttagtaga tttgtgcttg
    27541 tttttttgtt tacgataact taaggaaata tgttacctga ataataaatt tatataataa
    27601 aagtatataa atatatatat gaatgttaag attagttgat agaatttaaa taataaatcc
    27661 aatattataa acataggagg tatgaaaaat atgattaatg agaatttaaa aagtctaaga
    27721 aaaatcaacc agtatacaca agaagaatta gctgaaaaac ttaatgtttc tagacaatca
    27781 atagcaaaat gggaaagtgg agaatctatt cctgatatat gtagttgcat taaacttgca
    27841 aaattgtaca atgtcaaact agatgactta gttaatcatt cagaagaaaa aacaggtatt
    27901 atagtacctc ctaaaggaaa gtttttcttt ggagcagttg tagttggtga acgtggtcag
    27961 attgtcattc caaaagaagc aagagaagta tttaatataa atgcaggaga taaattattg
    28021 gtacttggag atgaggaaag aggattagga attgttcatc aacgtgattt gataaatttt
    28081 ataggtcatg tgggagtagt acgtaaagaa gaatgattta aaaaaattat aaaaggaggt
    28141 atgaaatatg agtaaaatag tattttttag cattcctgca tatggtcata ctaatcctac
    28201 tattgaagta gttcgtgaat tagtggatag aggaaatgag gtattgtatt attcttttaa
    28261 tgaatttaaa gataaaattg aaggtgctgg agcaaaattt atttgttgtg ataaatacct
    28321 tccagaatta ctccctggag atgagaaaaa aattggtaag gattttcctg gattaattga
    28381 gatgatagta gatactacta tttctttaga tgaaaaagtt tgtagagaac ttaaagattt
    28441 taatccagat tgcattgtat cagattcatt aagtttttgg ggaaagttat ttgcacaaaa
    28501 acttaatatt ccatatgtat gctctacaac aacttttgca tttaataaac atacagcaaa
    28561 gttgatgaaa caaaacttta tagaaattat acgtatgatt tttggtgtaa gacgcattaa
    28621 taaaaaaata aagcttttac aaagaaaagg gtatgaagta aaaaatttta tttctatagt
    28681 ttctaatgat aatgatacgg ataccattgt atatacatca aaagaatttc aaccaatggt
    28741 agaaaccttc tctagtaagt attcatttgt aggtccatca gtatcaaagt tgattattga
    28801 acctaaagag agaaaaagaa agctaatata tatttcgctt ggtacaatta ataataaaaa
    28861 tgttagcttt tataaaaact gtataagtgc atttaaagat tctgatgttg atgtgattat
    28921 gtctgttggt agaagtactg atattaaaag tttaggaaat ataccaaata attttgaggt
    28981 caaaaatagt gttgaacaga ttgctatact tcaaaaaact gatgtgtttg ttactcattc
    29041 tgggatgaat agtgttaatg aaagtttata ttatggagta cctatggtat tatttcctca
    29101 acattcggag cagagaatgg tagctaagag agttgttcat ttgggagcag gaattatgtt
    29161 aaaagaggat aagtcagaaa gtattaaaaa agcagtattt caagttataa atgacaatga
    29221 atataaagaa aatgcaacta aactatcaaa aagcttttat aatgcaggag gctcaaaaaa
    29281 agcagcagat gtaatattac agattatatg taatagtaga caagttgaca tataatagat
    29341 ttgttaaaaa tatatataca tacatgtaat ttaatcaaag tactgacagt ggggtctttt
    29401 aacctaccag ttggggcata tatattgatg ctaaatatga gggatgttat attttaataa
    29461 aaaagataac atcctttttt tagtgcatta tatcgagttt taaataataa atgaaggagg
    29521 attaatatga aaaaatataa agttattttt atagtattaa ttataggtat tataagtgta
    29581 acagggtttg ttgtatataa aaactgcatt aaaccatgga aagatgctga aacatatatt
    29641 gataagtata tggtaaaaca agatatttca aaagataata taaaaagtat tacaaaagaa
    29701 aaagccaaga aggcaagtta cgaaggaata ctatacaaag tgtattacaa agatgaccct
    29761 cgatatgagt atcaatattt ttatagtgat aattattatg ctctatatgt aaataaagta
    29821 atgttacaaa tttatgatat ggaaaataat aataaacttt taagaagtaa tgaggaatta
    29881 aaaagtgtaa agtatccact aatatatctt aaatataagc cagataaatg atttatgaca
    29941 aaatagaatg atttttatta aaatttattt aaaaatatca ctagagcgtt taaataaaac
    30001 taaatttaag tatttatata ttagtatatc ttactagtgt ttaaacaaaa ttaaatttaa
    30061 gtatttatat attagtatat cttactagtg tttaaataaa act
//
LOCUS       DAJMZY010000041        29917 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.041, whole genome shotgun sequence.
ACCESSION   DAJMZY010000041 DAJMZY010000000
VERSION     DAJMZY010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 29917)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29917)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29917
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.041"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            complement(60..1148)
                     /locus_tag="OE968_001806"
     CDS             complement(60..1148)
                     /locus_tag="OE968_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219087.1"
                     /translation="MNFNFAKATNSRLMGSLGLIINWIDDENNHFCQYFLLDAEGLGL
                     ADYVSLNNPTQEEAYMEEERLMGGFGSDRVELTKDESLFLVSYFGNKNLYYDKLLPGD
                     KCEYIDIIKNYKTDLTIEKLYNKICKRVDEEVEFINYMTMRFIAWDRESLKYFSGSDE
                     IANMHITNINGTLLKNVVSDKGQGRYISEALYEDNDGYYICKIAFCISKCYETGFRIN
                     SLLVTDKEPMYDFEVFDEISKSEFVSVYSVNSPEEFAGVFYRENPFLLKSNMNEGIFF
                     TRFNFNNDHVKENVYIINNDMKAIYYLMGNKFFIGTYNENDCNYINEISQSNYSDYIK
                     FEEKFFFEQNALYDFAESGSLDFDDFLE"
     gene            1273..2001
                     /locus_tag="OE968_001807"
     CDS             1273..2001
                     /locus_tag="OE968_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family hydrolase"
                     /protein_id="HCP7219088.1"
                     /translation="MKNIAAFFDIDGTLYRDSLMVEHFKKLIKYDIIDQKNWYKHARD
                     TFMDWDKRQGNYDDYLLEICDLYVDSLKGLDKTCINFTSDQVIKLKADRVYKYTRSRI
                     EWHLNQGHIVIFISGSPGFLVEKMAKKYNVTDFLGSDYVFENNIFTGTVIPMWDSISK
                     NNAINDFVVKYDLDLSNSYAYGDTNGDINMLKRVGNPIAINPTKELLSQISLDEEISK
                     NVEIIVERKDIIYSLSTDVNIVDI"
     gene            complement(2203..2694)
                     /locus_tag="OE968_001808"
     CDS             complement(2203..2694)
                     /locus_tag="OE968_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219089.1"
                     /translation="MSIKVAYGGVLLALNVILLTLTNIIPVNTLFIMGLASLLVSIVI
                     MEWGFKSGIAFYIGSIVLGFIVMASKSQWIVYSLTFGIYGIVKYLIEKDRSIYIEYFM
                     KLVFANIMILILYFLLRTIVYIPINIFIIGSFEIAFIVYDYVYSSFIGYYNNRLRKML
                     FKK"
     gene            complement(2705..3148)
                     /locus_tag="OE968_001809"
     CDS             complement(2705..3148)
                     /locus_tag="OE968_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219090.1"
                     /translation="MYSNTYNNENFMRARSFIENSEFKKAYDFLKTLTDKCAEWYYLT
                     GFSAMNIGYYEEGEDFLKRAKFMEPENSEYSDALRSYTQYRNDYSNRADNYNRRRRND
                     LDGCCCCCCDDCCCCLGDDCCENCAKLWCLDSCCECFGGDLITCC"
     gene            complement(3138..3977)
                     /locus_tag="OE968_001810"
     CDS             complement(3138..3977)
                     /locus_tag="OE968_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219091.1"
                     /translation="MFGYVKINKMDLTFREYDYYKAYYCGLCKYLKRNHGEISRFSLN
                     YDITFLIVLLTAVYNPESISTEEVCIVNPFKKKKVITNDITEYAASMNILLTYYKLED
                     NLMDDKRIKDKLAYYIYKNKLKLAYEKYPEKAEYIKQQLNELNKLEKDKNINIDEVSS
                     IFGNIMGEVFVYKKDENERNLRMIGFNIGKYIYLLDAYEDLDEDFKKGRYNPFIEYID
                     KNDELKEKVKKIIVTSLGFLARGIDNLNLNKNVGIIENIIYSGVYLRYINILESRGGK
                     NVQ"
     gene            complement(4196..5581)
                     /locus_tag="OE968_001811"
     CDS             complement(4196..5581)
                     /locus_tag="OE968_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HCP7219092.1"
                     /translation="MDNLNKKFLMEYIDEIQGELRDISDKIWKNPELQYKEYYASNLQ
                     KECLKKHGFSIEGLEGMDTAFVASYGEGRPVIAVLGEYDALDGLSQKVSTTKEPIVDG
                     GAGHGCGHNLLGTGSIGAVIAVKELIKLKKLKGTIKYYGCPAEEDLSGKVLMIKKGFF
                     DGIDCAFSWHPFDINTPIRIPTLANYSVKFRYNGISAHAAQAPYNGRSALDAVELMNI
                     GCNYLREHIFDNCRVHYVTTNGGKMPNIVPDFAEVWYYIRGVKMEHVRDVFGRIVDIA
                     KGAALMTGTIMEYDIISGVYDYIPNTILTDILSQNMKLVGVQNYNEDDYYFADKLAET
                     VSIDKRSSVSSVLSGNKDITKMNLHDEVTDDTFTHNNCISLSLDIGDVSYIIPTAQCS
                     CSVWPIGISAHTWQSCASAGSDMGFKAMLLASKSISCSINDVMLDELVINKAKKELKD
                     TVGSFKYIPII"
     gene            complement(5754..6497)
                     /locus_tag="OE968_001812"
     CDS             complement(5754..6497)
                     /locus_tag="OE968_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytoplasmic protein"
                     /protein_id="HCP7219093.1"
                     /translation="MKKVLIVGESWVKNITHIKGFDTFVTTHYEEAVKWLKEAIESGG
                     YETVHMPAHVAADSFPYKLEELNEYDCIILSDIGSNTFLLSNSTFIDCNSNPDRLELI
                     KEYVNNGGALIMVGGYMSFTGIDAKARFGETAIKDVLPITMIDKDDRVEKPAGIIPEV
                     IDSEHPVLKGIPTEWPKFLGYNKTVARDNCPVLATIGGDPFVAVGEFGKGKSAIFSSD
                     CAPHWGPKEFTDWKYYNKLWVNMLDWLTC"
     gene            complement(6517..7779)
                     /locus_tag="OE968_001813"
     CDS             complement(6517..7779)
                     /locus_tag="OE968_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HCP7219094.1"
                     /translation="MKKILLDTLNSKKQEYIDYLKELVSIKTEDVGHGILGGFEKEGQ
                     EYIEKLANYIGFSVDRQEMSEELIKKAKNIYKEGNLGHNYQDRYNLICKYSDDLPGKT
                     IVFNGHVDTMPPGDISKWKYNPYRATEDNGKLYGLGTADMKSGLIASILAVKLIKDSG
                     LNVPGNVKIMSVVDEEGGGNGTINAVMNGIDGDCCIICEPSEQNLIVAHMGFVFFEVE
                     VKGVSLHCGSKWEGVNAIEKAMLLLQDIKELEHNWLMIYKHPLLPSPTINLGVINGGT
                     AGSTVPDKCVFNLCVHFLPNIMSYEQVVNDVTNVIMTRANGDLWLKDNKPNINIYQSG
                     LGFEMDKDSDFVVNAHKILEETLGKKLEIKGSTAGNDARVMKNLAEIPTLILGPGSIE
                     QCHSIDEYVEIKEYLDSILMYASLILNL"
     gene            complement(7963..8961)
                     /locus_tag="OE968_001814"
     CDS             complement(7963..8961)
                     /locus_tag="OE968_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose ABC transporter permease"
                     /protein_id="HCP7219095.1"
                     /translation="MSSITKHKEEKSSPLLTKLTSVFRDQGSAAVGLVIIFIIMSVAS
                     SNFLTLDNLINVGRQISINAILAVGMTFVIITGGIDLSVGAVIALVGTFWATTVVNYN
                     APIWVGMILALAIGTILGVIKGAIISTQKLPPFIVTLAMLTIISGASFVFTGGRPISV
                     NTDAFKMLGRGYIGPIPIPVIIMIIVVIAGHFLLKRTNFGRHVHAVGGNEEAARLCGV
                     KVNKVIVKVYALAGLLTALAGIILSSRLASGSPTVGDGAELDAIAAVVLGGTNMMGGS
                     GSIVGTCIGVGIIGILGNGLNLLSVSSYNQMIIKGLVMLFAIWINNIKLKKSAKSK"
     gene            complement(8945..10456)
                     /locus_tag="OE968_001815"
     CDS             complement(8945..10456)
                     /locus_tag="OE968_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HCP7219096.1"
                     /translation="MSNIILKLSNIAKEFPGVRALDNVNFELFHGEVHALLGENGAGK
                     STMIKILTGAHSKTSGKFIFEGKEIENISPDISKKIGINAIYQELTVFDELTVAQNIF
                     MGKEINGKVLTNDKKMNEEAKKIFDNMGIDINPNSLVKELSIAQKQMVEIARVLSSET
                     KVLIMDEPTSSISKKETEILFRLINDLKESGVSIIYISHRMEELFEICDRITIMRDGK
                     TISTLNTKDVSSEEELVNLMIDRKLDQFFPKRKVEIKEEIMRVENLTKNNVFNDISFN
                     IRKGEILGIGGLVGSKRSEIVEAIFGLRTYDSGKIYLNNEEVKFKTPSDAIENGLGLI
                     TEDRKGTGLFLQMSVKENTTMAGLKKISKFKSIIDRKKEKEILEKYIEALKIKTPHMN
                     QVIQSLSGGNQQKAIIARWLLLQPDILIMDEPTRGIDVNAKAEIYNLMGDLVESGVSI
                     IMISSEIPELISMSDRIMVMREGHISGFLEGEEMVENNVLKLAFGGKINEFNN"
     gene            complement(10510..11472)
                     /locus_tag="OE968_001816"
     CDS             complement(10510..11472)
                     /locus_tag="OE968_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HCP7219097.1"
                     /translation="MRVRKILSLGIAGILAIGMLTGCSMEGPSKSDNKGGSDKKDLTI
                     GVSTITLQHQFFIDIDEGIKEKAKELGVKVIVNDPDQDVAKQTSAIEDFIQQNVDGMI
                     VLGTDNSAIVPAVEGAFEKMPVVTVDAVLNTENITSYVGTVSYDAGKKLGEYTKKYID
                     EKLGGKSEIAIVTDLKSQIQMQRIDGFKDALKGSANVKILNSQPGYDREESLNTVENL
                     IQSNPDVDIIYATAENSVLGAKAALESAKNKDVKIVGFDLTEEASSGITDGTILAMIQ
                     QQPKEMGRLAVEAVVKAIKGEKVEKNIPVPALLYDKENIKDFKN"
     gene            complement(11520..12410)
                     /gene="rbsK"
                     /locus_tag="OE968_001817"
     CDS             complement(11520..12410)
                     /gene="rbsK"
                     /locus_tag="OE968_001817"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HCP7219098.1"
                     /translation="MGNIVVIGSVNMDMVCSVDKRPEKGETVLGNSFFTSPGGKGANQ
                     AISASKLGANVKMISCIGEDGLGEELIRNFRTNKVDYSLVSRNNHKSSGVAVITLCEN
                     DNSIVVVPGTNELVDIELIKKNEEEIKNADIVLLQLEIPLKTINYVVNFCFENRIRVL
                     LNPAPAVKLNEDIIEKVTYLTPNEHEYKIVFDTNEGIEEVLKKYPNKLVITEGKNGAR
                     FYDGEEIKHVSCISVDVQDTTGAGDTFNGALAVAITEGKNLYTAVEYAVVVSGLSVTK
                     LGAQSGMPYKEDVEKYLNNK"
     gene            complement(12452..13465)
                     /locus_tag="OE968_001818"
     CDS             complement(12452..13465)
                     /locus_tag="OE968_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCP7219099.1"
                     /translation="MSITIKEIGELAGVSKTTVSKVINNKDENISQATREKILKIMKE
                     KNYVPNKLAQSLVTKKTNTIGLLIPDIRNPFFTDVSRGVEDKANEEGYNIILCNTDED
                     AKKEYEGIRTLSERMIDGIIFAASSNTNWKEANYKDIKIPTVLIDKKISMNKETLKGI
                     VKINNFEGAYIATKHLLDIGNKKIIYLSGPLQNEIAVDRLEGYKKALIECNLSYNPAY
                     VFEGKYKIEWGQEFIKNLEKIDFDAIFCANDLIAIGVIRGLKERGLSIPNDISVVGFD
                     DIQTSSLISPSLTTVKQPSYDIGYKASEILINCLRGDKKESFDELIFKPELVIRDSTK
                     ESE"
     gene            complement(13693..14670)
                     /gene="bioB"
                     /locus_tag="OE968_001819"
     CDS             complement(13693..14670)
                     /gene="bioB"
                     /locus_tag="OE968_001819"
                     /EC_number="2.8.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin synthase BioB"
                     /protein_id="HCP7219100.1"
                     /translation="MEKYIIKLKNKVLREKEISYEEALNLISLDTNNKNDFDILLKSA
                     NEIREYFMGRKADLCTIMNAKSGKCSEDCKFCAQSSYYKTGVEEYSLLDYNEILNRAK
                     EMESKGVHRFSLVTSGKGMSGKEFNNILNIYEGLRENTNLKLCASLGIIDYEQAKMLK
                     SAGVTTYHHNVETCRDNFHNICTTHTYKDRIKTIKDAKKAGLDVCVGGIIGMNESEEQ
                     RLKMAFEIRELNVKSFPINILNPIKNTPMENYDVLEPMEILKTTAVFRFIIPNVYIRY
                     AGGRLSLKGYDKVGFNGGVNSAIVGDYLTTVGSGIENDKKMIIEQGFEL"
     gene            complement(14876..15139)
                     /locus_tag="OE968_001820"
     CDS             complement(14876..15139)
                     /locus_tag="OE968_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219101.1"
                     /translation="MKIYYEKENSKKANVNNIPSVFAFNFLRNFLTSKEYEETRKEYF
                     INNLTKSQVNQAMKDLKWLFREYEGLEVITMESLDGVKTRIVL"
     gene            complement(15209..16282)
                     /locus_tag="OE968_001821"
     CDS             complement(15209..16282)
                     /locus_tag="OE968_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF362 domain-containing protein"
                     /protein_id="HCP7219102.1"
                     /translation="MEKSKVYFCDLYSNSQNKNVPNNVRRLFDEAGFKDLIEKNDQVA
                     IKLHFGEKGNTTYMSPVAVRQVVDKVKDCEGKPFLTDTNTLYTGSRTNSVDHLTTAIE
                     NGFAYAVVNAPVIIADGLYSRNYENVKIDKKHFESVKIGGEIYNSSAMIVMSHFKGHE
                     AAGFGGALKNLAMGCASAAGKQMQHSDVTPVVKEKKCVGCGKCVNSCPTKAISIVDKK
                     AVIDSDVCYGCGECPTVCPTRAVTIQWESDSDVFVEKMAEYAYGAVSNKKDKVGYITF
                     VMNVTPLCDCVPWSGRPIAHDIGILASTDPVAIEQACYDLICKEMGHDVFKHEHPHVN
                     GTRIIDYACEMGMGSKEYELIKL"
     gene            complement(16541..17299)
                     /locus_tag="OE968_001822"
     CDS             complement(16541..17299)
                     /locus_tag="OE968_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCP7219103.1"
                     /translation="MREYIAFTKKEFKENLRNYKLFSLIILFLIFGISSPISAKFMPD
                     LIAHFAPTLKVTAAPTALDSWTQFFSNISGLGMSLTLIIFCNILSNEYSKGTLVIMLT
                     KGLSRSSIVLSKFSVTVIIMTIGFWLSFLFAYGYTMYFWPTANLNHIIFSAFNLWLIG
                     IMYISVLILGCVLFRPAFASVLLVLVATLLLSLISIPKQIAPYTPNFLMSKNIDLISG
                     KVAMPEFIIPIIITVLISIVCLLAAVILFNKKPV"
     gene            complement(17296..18213)
                     /locus_tag="OE968_001823"
     CDS             complement(17296..18213)
                     /locus_tag="OE968_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCP7219104.1"
                     /translation="MNIVSINGLSKGFGNRKIIDNLNFTVPEGSVFGFVGKNGAGKTT
                     TMKMVLGLLKPDSGTIDVCGEKVTYGKTSSNRHVGYLPDVPEFYNYMRPLEYLSLCGE
                     ITGLSKKEIQIRSEELLSLVGLRNEKRRIGGFSRGMKQRLGIAQALLSRPKLLICDEP
                     TSALDPVGRKEILDIMLKIKDSTTVIFSTHILSDVERICDHVAILNKGSIALSGTLSE
                     IKSMHGKDRLLLEFASNDEIQKFKSSDGIKSLLKDSEETNMEIVLHGKDIKAIQKTVI
                     STLAEMNLCPVKMELIELSLENLFLEVVK"
     gene            complement(18213..18413)
                     /locus_tag="OE968_001824"
     CDS             complement(18213..18413)
                     /locus_tag="OE968_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLDc_N domain-containing protein"
                     /protein_id="HCP7219105.1"
                     /translation="MENLMEYLPLLVPVIILDLILIITALVHVLRHPNYKIGNKAIWI
                     IVVLFISLIGPILYFTIGRGEE"
     gene            complement(18418..19512)
                     /locus_tag="OE968_001825"
     CDS             complement(18418..19512)
                     /locus_tag="OE968_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCP7219106.1"
                     /translation="MNELNIAKTLILKRKEKGITQDELANYIGVSKASVSKWETGQSY
                     PDITFLPQLATYFNITVDELICYEPQMMKEDINKLYNKLCKDFTVKPFDEVMDEIREI
                     IKKYYSCFPLIFRMGLLIVNHYDIVDEKKRELLISEALEIFIRIQETCNDIDICRQAK
                     SMEATCYILLNQPIQVIDLLQNSNFPMINESILLAQGQMMNGQMDEARETFQLGAYQN
                     LISLVQNLVGILQNADKLQMKEIERRILAISDIFELDTLSPAIMLSSYLTQAQINLIH
                     GDNEGAIKSLRKYVDLATRDIYPIIIHGDDFFNKLDRWISEIGTGITRDDTIVKAGIV
                     AAIKNNPMFSVLSENKEYKFLIEKLSLLEE"
     gene            complement(20022..20162)
                     /locus_tag="OE968_001826"
     CDS             complement(20022..20162)
                     /locus_tag="OE968_001826"
                     /inference="COORDINATES: protein motif:HMM:NF021468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2185 domain-containing protein"
                     /protein_id="HCP7219107.1"
                     /translation="MNGEGCILSNKITKECYKVGYMIREKSIDIYPDSGWGFMTWDEN
                     GE"
     gene            complement(20472..21779)
                     /locus_tag="OE968_001827"
     CDS             complement(20472..21779)
                     /locus_tag="OE968_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HCP7219108.1"
                     /translation="MDISRSVDNSLNRTIEFLKELIKIDSQQGEPISQCPFGIGPKKS
                     LDKTLDYCASLGFSVKNIDNYIGYAEIGEGEELIGIPMHLDIVPPGEGWSVDPFSGAV
                     IDNIIYGRGVIDNKGAVSMLIHVLKNIEDMYPTINKRIRLIFGTNEETGMKCIKYYLD
                     KGEEIPSMGFTPDAMYPVVNGEKGRVHIRIEKEIKIDKSKPYIIVSGGTKENVVPSHC
                     TAKIINGIISELTTKGVAVHASNPEKGENAISKMVIKIVEDNMDFQHREDIELVSKYL
                     CSDYYGDALGINQYDEVFKNTTLNLGILKVNEEKIVCELDIRYGKNIVLNNIIDRFKK
                     VFCNGWKIEVIVHKDLHYVDESNLVLKKLLEAYEEVTDENGYTIAMGGGTYASWFKDM
                     VAFGPKFLAYKTGGHGVDERVPINHIRKNMEIYTLALIKLLEL"
     gene            complement(21844..22323)
                     /locus_tag="OE968_001828"
     CDS             complement(21844..22323)
                     /locus_tag="OE968_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-2-amino-thiazoline-4-carboxylic acid
                     hydrolase"
                     /protein_id="HCP7219109.1"
                     /translation="MSEKMYTEKEYLEGIRGATGERAVWFYLLMKEAEKLGANPDDIC
                     KEAIYGFGKMRGQKYNVADTPGKMAEMLYNSKGQKVFEMELVENTDENGVLKFHHCPL
                     DAAWKEYGLTKEERKEICRLACYGDYGRVDCAQGVKLDFAQKCAHDDEVCELVFTKK"
     gene            complement(22370..23233)
                     /locus_tag="OE968_001829"
     CDS             complement(22370..23233)
                     /locus_tag="OE968_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HCP7219110.1"
                     /translation="MQEIKNKEVKNGQGPTEVNKTRVLTKKDVTKTYLRWWWTAELSN
                     SFERMQALAVCASFTPALEKLYKRKEDLVDALKRHLQFFNTQAIWGGLIHGTVLAMEE
                     EKATEGKIPGEVISGVKNGLMGPLAGIGDTLDFGTFQTIFLALGASFGAEGSVIGAFF
                     PIMFSILLFCEGYYLFHLGYSLGRDSIKKILSGGIVNKIIDGASILGMFMMGALSATT
                     VKLSTPLSFDIGGKAIVVQDTLNMIAPGLLPLGVVFFVYWGMKYKKWTITKLLVILVV
                     LALVGSFIGIF"
     gene            complement(23233..23988)
                     /locus_tag="OE968_001830"
     CDS             complement(23233..23988)
                     /locus_tag="OE968_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCP7219111.1"
                     /translation="MESVLMLAIVTGLWYWFAAGLAGYTLFSTLKSPLFIGFSLGLLW
                     GDVTTGMIVGASIEMVYLGMVAAGGNIPSDKCLAALIAIPVALQTGVNAEVAVSIAVP
                     LGVIGVLVNNLRRTGNAVLVHKADKYAEEGNTKGIWRCATLYSLIFGFVLRFPIVFVC
                     NFFGADLVQSLLDVIPQWLMNGLTVMGGILPALGFATTIFTIGKNKFLPMFIIGFFMV
                     QYFEISITAAAIFGVCIALLITFMKEDKRVGEV"
     gene            complement(24015..24503)
                     /locus_tag="OE968_001831"
     CDS             complement(24015..24503)
                     /locus_tag="OE968_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCP7219112.1"
                     /translation="MAKITLVRVDHRLIHGQVITKWVKIAQAQKIIIVDDFLGQDEFM
                     ADIYKMAAPSGVEVVILTAEDAGQAFQNNTLGDKNIFILFKNVDMANKAYKAGLKYEK
                     IQLGGIPNEAGKKMVFTAVSLGNEDVEQLNELNENGVEIVLQVIPEESSMTYENALKK
                     FK"
     gene            complement(24521..24922)
                     /locus_tag="OE968_001832"
     CDS             complement(24521..24922)
                     /locus_tag="OE968_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIC"
                     /protein_id="HCP7219113.1"
                     /translation="MNKYKVIILCHGTWGKVLVEETNKNFGLSNQYEVLSLSSEKDVS
                     VFMKEVEEVVDKEDVKIIISDLYGGSTSSVAIAVAIRRGIDAINGLSLQTILIVDEEL
                     SKEDKLHTLPERIVKKNNNLCVDLIKEFKKI"
     gene            complement(24925..25422)
                     /locus_tag="OE968_001833"
     CDS             complement(24925..25422)
                     /locus_tag="OE968_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCP7219114.1"
                     /translation="MSLVKYCRCDDRLIHGQVIYKWVKHLGVKKIVVVDDETTNDVIA
                     KGLIKMAAPKNIDLSILTVSESRRYFYNNQADDNVFVLIKNLDTANRMIEEGINIKKL
                     IVGRIPTGIGKKKISQNVYINKKEFLLIDEFIKKNINVSIQMVPDEEEVELNQNINRY
                     KGEFI"
     gene            complement(25446..25850)
                     /locus_tag="OE968_001834"
     CDS             complement(25446..25850)
                     /locus_tag="OE968_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HCP7219115.1"
                     /translation="MIGIIVMTHGSFSEEIIKSCELIAGPAERTAAIKLNRNDNIEDL
                     NKNFVEKLNELDEGDGVLVLADLLGGSPSNVASLNLKKGGKFHALTGVNLPMLLEALI
                     NREGKSLEELAEACIEAGQTGINNINKVLSSM"
     gene            complement(26080..28647)
                     /locus_tag="OE968_001835"
     CDS             complement(26080..28647)
                     /locus_tag="OE968_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HCP7219116.1"
                     /translation="MTQKKLSRKEKVLICLKRLTEEHLNFNNGIRFGFDAEYIATEVG
                     INRSNASKELNQLIKESIIIKIKGKPVQYLYKESIESILGKKLNKGIFDNINSINEYS
                     ENDSIKDEYILESIKKENNIFNLVGCDGSLRSQIEQAKAAVIYPPKGLSTLIIGPTGV
                     GKSIFAEYMYKYSLTIKEDSDNAPFIIFNCADYSDNQQLLLAQLFGYVKGAFTGADKD
                     KYGIVHEANNGVLFLDEVHRLSAEGQEMLFLLMDKGIYRRLGEANKVHECRVMIIAAT
                     TEDPETAMLETFLRRIPVTIKIPSLEERGFQERMKLICYFFKEESVRIGVKLKVSKEV
                     IKAFILYKCKGNIGQLKSDIQLICARAFLDYMTYKRECVYVRLSLLPNNIRESLYGNN
                     RKEEFVQNFSFIGKDDIIFLPEEKDFESENLLIENKKYDLDFYGMIKETWNKLQQEGI
                     KESQIRSVIDGDIQKYSYNLMNTFIYNSSNQTAYNNIVNDSIATTVKYILQKHDKWSK
                     REGLDKLIKAIALHIQNLIERIKIGNIVKHPNKDEIMKERAYEYNIAKEILSNMSLMY
                     GVEFPEDEAIFLATFLYLSYVGLNEESIAILVIMHGESTASSMVNVANTLLDCNHAVA
                     INMGLEDRVQDILVQAVEIANKIDKGKGILILTDMGSILTFAKVIRDATGKEVKAIDM
                     VSTPIVIEATRKALTPEMTLEKLYFNIIESIKKHYGDMEVTYAEKDNGGRYFDRLLID
                     NISKTLTFLNGEKAYFILKEVINRISEHYSLVIQDELLVKFIFHCSCMIERVIIKESL
                     VYKSYEERISRNKELYLVIKESFKLVEETFDIIISDMEYANILDIFESQYDTDKFKS"
     gene            28813..29556
                     /locus_tag="OE968_001836"
     CDS             28813..29556
                     /locus_tag="OE968_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase"
                     /protein_id="HCP7219117.1"
                     /translation="MNFLSDLHTHSIVSGHGYSTLLENINYCKENGIKILGTSEHGPK
                     MPGSPHRWYFHNIQNIPRIINNIIILRGCEANILDIKGNIDLEPFVIPRLDYLILSFH
                     EAVFSPNTLENNTKALINAINKHDNIEILGHLGNPNYPIDYELIIKLAIEKNILIEIN
                     NCSIKGVSRNGSSDNCKYIATLCKKYGAKIILTSDAHICFDIGNYEYSENILKEINFP
                     DELIMNYPKKLINHFHQKGKLLDVDYTNI"
BASE COUNT         9605 a         5530 c         3047 g        11735 t
ORIGIN      
        1 gaaataaatt taagcgagat taaattcagt taatctcgct taaataatgt ctaaatttat
       61 tattccaaaa aatcatcaaa atctaatgaa cctgattctg caaaatcata taatgcattt
      121 tgctcaaaga aaaatttctc ttcaaattta atatagtcgc tataattaga ttgacttatt
      181 tcattgatat aattgcaatc attttcgtta taagtaccaa taaaaaactt atttcccatt
      241 aagtaatata tagctttcat atcattattt attatatata cattttcttt tacatggtca
      301 ttattaaaat taaatctagt aaagaatata ccttcattca tattactttt taacagaaat
      361 ggattttctc tataaaatac tcctgcaaat tcttcaggtg aatttacact gtaaacactt
      421 acaaattcac ttttagaaat ctcatcaaat acctcaaaat catacatagg ttctttatct
      481 gtcactaata gagaattaat tctaaaacca gtttcataac acttacttat gcaaaaagca
      541 attttacata tataatatcc atcattatct tcatataaag cttcacttat atatctgcct
      601 tgacctttat cacttaccac gtttttaagt aatgttccat ttatattagt aatgtgcata
      661 tttgcaatct cgtcacttcc agaaaagtac tttaaacttt ctctatccca tgctataaat
      721 ctcatggtca tatagtttat aaattcaact tcctcgtcaa ctcttttaca tattttattg
      781 tataattttt ctatagttaa atctgtttta tagtttttta taatatcaat atactcacat
      841 ttatctcctg gcaatagctt atcataataa agattcttat taccaaaata agatactaaa
      901 aataaagatt catccttcgt taattcaact ctatctgaac caaatcctcc catcaatctt
      961 tcttcttcca tataagcttc ttcttgtgtt gggttattta aactcacata atccgctaat
     1021 cctaatccct ctgcatctaa taaaaaatat tgacaaaagt gattgttttc atcatctatc
     1081 caatttatta taagacctaa actgcccata agtctagaat ttgtagcctt tgcaaaatta
     1141 aaattcatat agtcacatcc tttaaactct aaaatacttg ttttttaata tataaattat
     1201 tatacatata ttttaacaac ttagatacaa tttataatat aatataagga aatgattaat
     1261 tgaggtggtc ttatgaaaaa tatagcagct ttttttgata tagatggtac tctttataga
     1321 gactctctta tggttgaaca ttttaaaaaa ttaattaaat acgatataat tgaccaaaaa
     1381 aattggtata aacatgctag agacactttt atggattggg ataaaagaca aggtaattat
     1441 gatgattatc tattagaaat atgtgacctt tatgttgatt cactaaaagg attagataaa
     1501 acctgtatca actttacaag tgaccaagta attaaattaa aagcagatag agtttataaa
     1561 tacacacgtt caaggattga gtggcatcta aatcaaggac acatagttat atttatatct
     1621 ggtagccctg gatttcttgt tgaaaaaatg gcaaaaaaat ataatgtaac cgattttcta
     1681 ggaagtgatt atgtctttga aaacaatata tttacaggca cagttattcc aatgtgggat
     1741 tctataagta agaataatgc tataaacgat tttgttgtaa agtatgattt agatttatca
     1801 aactcgtatg cctatggaga tactaatggt gatataaata tgctaaaaag agttggaaat
     1861 ccaatagcaa taaatccaac aaaggaactt ttatctcaaa tatcacttga tgaggaaatt
     1921 tctaaaaatg ttgagataat agtagaaaga aaagatatta tttattctct atctacagat
     1981 gtaaatatag tggatattta atttatacta tctattttaa aaacttatat tatatctaat
     2041 atttatatct aacatataaa agctttgact aaaaatcaaa gcttttatat gttgcactaa
     2101 gaatatatta aatttagctt tatgctttaa tgtatattca tatatatcat ttacacttat
     2161 ctaaactaca atttcattaa aattaaatat aaaaatcaac tattattttt taaatagcat
     2221 ctttcttaat ctattattgt aataacctat aaaagaactg taaacatagt catatactat
     2281 aaaggctatc tcaaatgaac ctataataaa tatgtttatt ggaatataaa ctattgttct
     2341 taataaaaaa tacaatataa gtatcattat atttgcaaat actaatttca taaaatactc
     2401 aatatatata gacctatctt tttctataag atattttaca ataccatata ttccaaaggt
     2461 aagtgaatat acaatccatt gagacttact tgccatcact ataaatccta aaactataga
     2521 acctatataa aaagcaattc cactcttaaa gccccattcc attattacaa ttgatactaa
     2581 aagtgatgct aaccccataa taaacaatgt atttacagga ataatgtttg taagagtcaa
     2641 caatatcaca tttaatgcta ataaaactcc tccataagca acttttatac tcatatttat
     2701 catcctaaca acaagttatt aaatctccac caaaacattc acaacatgaa tctaaacacc
     2761 aaagtttagc acaattttca caacaatcgt cacctagaca acaacagcaa tcatcacagc
     2821 aacagcaaca acatccatct aaatcattac gtcttcttct attataattg tcagccctat
     2881 tgctataatc atttctatat tgtgtataac ttctaagtgc atcactatat tcactatttt
     2941 caggctccat aaattttgct ctttttaaga agtcttcacc ttcttcataa tatcctatgt
     3001 tcattgcaga aaaaccagtt aaataatacc actctgcaca tttgtcagtc aaagttttta
     3061 aaaaatcata tgctttttta aattcactat tttctatgaa tgatcttgct ctcataaaat
     3121 tttcattatt ataagtatta ctgtacattc tttccacctc tactttctaa tatattaata
     3181 tatcttaaat aaacaccaga ataaattata ttttctatta ttccaacatt tttatttaga
     3241 tttagattat caattcccct agctaaaaat cctaatgatg ttactattat tttttttact
     3301 ttttctttta actcatcatt tttatcaata tactctataa atggattata tcttcctttc
     3361 ttaaaatctt catctaaatc ttcataggca tctagtagat atatatactt acctatatta
     3421 aaacctatca ttcttaagtt tctctcattt tcatcttttt tatagacaaa tacttcaccc
     3481 attatatttc caaatatact agatacttca tctatattta tatttttatc tttttctaac
     3541 ttatttaatt catttagttg ttgttttata tactctgctt tttcaggata cttttcatat
     3601 gctaatttta atttgttttt atatatataa tatgccaatt tatcttttat gcgtttatca
     3661 tccattaaat tatcttccaa tttataatac gttaaaagaa tattcatact tgctgcatat
     3721 tctgtaatat catttgtaat tacctttttc tttttaaatg gatttactat acacacttcc
     3781 tctgtactta tagactctgg gttatatact gctgttaata aaacaattaa aaatgttata
     3841 tcatagttca aagaaaacct agagatttct ccatgatttc tttttaagta tttacatagt
     3901 ccacaatagt aagctttgta ataatcatat tctctaaatg ttaaatccat tttgtttatt
     3961 ttaacatatc caaacataaa tactcctttt tgtactattt tttatttaga ttatatatag
     4021 tataacactt tttatcaaga ttatataatt tacagtattc taagaaactt aaaaaattcc
     4081 ttctaatcat tgtatcttaa atttaaaata attagaaggt tgggttaaaa ataatattaa
     4141 attatatact tatattaact catacaagtt agttatgctt atatcaattt aagttttaaa
     4201 taattggtat atatttaaaa ctacctacag tatccttcaa ttcttttttt gctttgttta
     4261 taaccaattc atcaagcatt acatcattta ttgaacatga tatagattta gatgccaata
     4321 acattgcctt aaatcccata tcagaacctg cactggcaca agattgccat gtatgggcag
     4381 aaataccaat aggccaaact gaacaagaac actgtgctgt aggaattatg tagctaacat
     4441 ctccaatatc taatgataat gatatacagt tattatgagt aaatgtatca tccgtaactt
     4501 catcatgcag attcatctta gtaatatcct tatttccact taatacacta gaaacactac
     4561 ttcttttatc tatagacact gtctcagcta atttatctgc aaaatagtag tcatcttcat
     4621 tatagttttg cacacctact aatttcatat tttgtgatag aatatctgtt aatattgtat
     4681 ttggaatata gtcatatact ccacttataa tgtcatattc cataatagta ccagtcatta
     4741 atgctgctcc ttttgctata tcaacaatcc taccaaatac atctcttaca tgctccattt
     4801 taactcctct tatgtaatac cacacttctg caaaatcagg aactatattt ggcatttttc
     4861 caccattagt agttacatag tgtactctac aattatcaaa tatatgttct ctcaaataat
     4921 tacaacctat attcataagt tctactgcat caagtgcact tcttccgtta taaggagctt
     4981 gtgctgcatg ggcactaatc ccattatatc taaatttcac agagtaatta gcaagtgttg
     5041 gtattcttat tggagtattt atatcaaatg gatgccaact aaaagcacaa tcaattccat
     5101 caaaaaaacc tttttttatc atcaatactt ttccagataa atcttcttct gctggacatc
     5161 catagtattt tatagtccct ttcagctttt ttagtttgat taattccttt actgcaatta
     5221 cagctcctat tgaacctgta ccaagtaagt tatgtccaca tccatgacct gcaccaccat
     5281 ctacaatagg ttctttagta gtggatactt tttgagacaa accatctaaa gcatcatatt
     5341 ctcccaaaac tgctataact ggtctacctt ctccataact agccacaaat gctgtatcca
     5401 taccttctaa tccctctata ctaaaaccat gtttttttaa acattctttt tgtaaatttg
     5461 aagcatagta ttctttatac tgaagttctg gatttttcca tatcttatct gatatatctc
     5521 ttaattctcc ctgtatctca tctatatatt ccatcaaaaa ctttttattt aaattatcca
     5581 tattaattat ataaacctcc ctgtttctaa taacttatcg attatcagcc aaaatgacta
     5641 attttaactg atttaaaaat attttctacc atacaaccat tttatacaat aaaacctctt
     5701 gacttgtaag tttcatttta tcaagtaaga ggttttcaag ttttataaaa tttttagcat
     5761 gttaaccaat caagcatatt aacccataat ttattatagt atttccaatc agtaaattct
     5821 tttggacccc agtgaggtgc acagtcagaa ctaaagatag cagattttcc ttttccaaac
     5881 tcgccaacag ctacaaatgg gtctcctcca atagttgcta aaacaggaca attatctcta
     5941 gctactgttt tgttatatcc taaaaacttt ggccattctg ttggtatacc ttttaatact
     6001 ggatgttcag agtcaataac ttctggaatt attcctgctg gtttttcaac tctatcatct
     6061 ttatctatca ttgttattgg taatacatct ttgatagcag tttctccaaa tctagctttt
     6121 gcatctattc ctgtaaatga catatatcca cctaccatga ttaacgcccc accattattt
     6181 acatactctt tgattagttc aagtctatct ggattactat tgcaatctat aaaagtacta
     6241 ttagataata agaacgtatt agaacctata tcagataata ttatacagtc atactcattt
     6301 aactcttcta atttatacgg aaaactatct gctgctacat gtgcaggcat atgaactgtc
     6361 tcatatcctc cagattctat tgcttctttc aaccacttta cagcttcttc ataatgagtt
     6421 gtaacaaacg tatcaaaccc ttttatatga gttatatttt ttacccaaga ttcccctact
     6481 attaatactt ttttcattta tatattcctc ctacttttat aagtttaata ttagacttgc
     6541 atacataagt atactatcta aatactcctt aatttcaaca tattcatcaa ttgaatgaca
     6601 ttgttctatt gaacctggcc ctaatataag tgttggtatt tcagctaaat ttttcattac
     6661 tctcgcatca ttgccagctg ttgaaccttt tatctctaat ttttttccta gagtttcttc
     6721 tagtatttta tgtgcattca ctacaaaatc agaatccttg tccatctcaa aacctaaccc
     6781 tgattgatat atgtttatat ttggtttatt atctttaagc cataaatctc cattagccct
     6841 tgtcattatg acatttgtta catcatttac aacttgttca taactcatta tatttggcaa
     6901 gaagtgtaca cataaattaa atacacactt atctggcaca gtagaacctg ctgttccacc
     6961 atttattaca cctaaattta ttgtaggtga aggtaatagt ggatgtttat atatcataag
     7021 ccagttatgt tccaactctt ttatatcttg aagcaacaac atagccttct caattgcatt
     7081 tacaccctcc cacttactac cacagtgaag agacacacct ttaacctcaa cttcaaagaa
     7141 tacaaatccc atatgtgcaa ctattaagtt ttgttctgat ggttcacaaa ttatgcaaca
     7201 atctccatca ataccattca taactgcatt tatggtacca tttccgccac cttcttcatc
     7261 tactactgac attattttta cattaccagg tacatttaga ccactatctt ttataagctt
     7321 tacagctaat attgatgcta taagtccaga tttcatatca gcagttccaa gaccataaag
     7381 ttttccatta tcttctgtag cacgatatgg attatatttc cacttactta tatcacccgg
     7441 tggcatagtg tctacatgac cattaaatac aattgtctta ccaggtaaat catcactata
     7501 cttacaaatt aaattatatc tatcttgata attgtgacct agatttcctt ctttatatat
     7561 attttttgct tttttaatta attcttcgct catttcttgt ctatccacac taaaacctat
     7621 gtaatttgca agtttttcaa tatattcctg tccttctttt tcaaatccac ctagtattcc
     7681 atgaccaaca tcttcagtct ttatacttac aagttctttt aaataatcta tgtattcttg
     7741 ttttttacta tttaatgtat ctaagagaat ttttttcata tttcctccta agatttattt
     7801 ttacatttaa aatttcaagt ctaatctcat ctatttaagc catagtaaac tttttcactt
     7861 agcatattct cattcaatgt ataaagatgt atgcaaatta aagtataaaa atatatacaa
     7921 aaacttaata atttttatag tttataagct aaaatttaat tactatttag atttagctga
     7981 tttttttaat tttatattat ttatccatat agcaaataac attaccaaac cttttataat
     8041 catttgatta tatgaagata cacttaataa gtttaatcca tttcctaata ttcctattat
     8101 tccgacacct atacatgtac ctactataga accagaacca cccatcatat tagtaccacc
     8161 aagcacaacg gctgctatag catccaattc tgctccatct ccaacagttg gtgaacctga
     8221 tgccaaacgt gatgatagta ttatcccagc taatgctgtt agtagtccag ctagtgcgta
     8281 tacttttact ataactttat ttacttttac tccacataat ctagcggcct cttcatttcc
     8341 acctactgca tgtacatgac gtccaaaatt agttcttttt aatagaaaat gtcctgctat
     8401 tacaactata atcataatta taactggtat tggtattggt ccaatatatc ctctaccgag
     8461 catcttaaat gcatctgtat ttactgatat aggtcttcct cctgtaaata caaagcttgc
     8521 cccacttatt atcgttaaca tggctaaagt tacaatgaat ggaggtagtt tttgtgttga
     8581 aataattgca ccttttatga ctcctaatat tgtccctatt gctaatgcaa gtatcatacc
     8641 tacccatata ggtgcattat aattcactac tgttgtagcc caaaatgtac ctactaaagc
     8701 aattactgct cctacactta aatctattcc tcctgtaatt attacaaatg tcatacctac
     8761 tgcaagtatt gcatttattg atatttgtct tccaacatta attaaattat ctaaagttaa
     8821 aaagttagat gaagctacac tcattattat aaaaattatt acaagtccta cagctgcact
     8881 cccttggtct ctaaatacac ttgttaattt tgtcaataat ggagaagatt tttcttcttt
     8941 atgcttagtt attgaactca ttaattttac ctccgaaagc caattttaat acattatttt
     9001 caaccatttc ttcaccttct aaaaatccac ttatatgacc ttctctcata accattattc
     9061 tgtcactcat tgatattaat tctggtattt cagaagatat cattattata cttacaccac
     9121 tctccactaa atctcccatt agattgtata tctctgcctt agcatttaca tctatacctc
     9181 tggttggttc atccataatc aatatatctg gttgtaataa aagccatctt gctattatag
     9241 ctttttgttg gtttccacca cttaaacttt gtataacttg attcatatgt ggtgttttta
     9301 tctttaaagc ttctatgtat ttttctaaaa tctctttttc cttttttcta tctataattg
     9361 atttaaactt agatatcttt tttaacccag ccatagttgt attttctttg acactcattt
     9421 gtaaaaacaa tccagtacct tttctatctt ctgttattaa tcctagtcca ttttctattg
     9481 catctgatgg agttttaaac tttacttctt cattgtttaa atatattttt ccagaatcat
     9541 atgttctaag tccaaatata gcttctacta tttcacttct cttacttcca actagtccac
     9601 ctattcccaa tatttcacct tttcttatat taaagctaat atcattaaaa acattgttct
     9661 tagttagatt ttccactcgc ataatttctt cttttatttc tacttttctt tttgggaaaa
     9721 attggtctag ctttctatct atcattaaat taactaattc ttcctcagac gatacatctt
     9781 tggtatttaa agtcgaaatc gttttcccat ctcgcattat agttattctg tcacaaatct
     9841 caaagagttc ttccatccta tgggatatat atattatact aactccactc tcttttaaat
     9901 catttataag tctaaaaagt atttcagtct cttttttact tattgaagaa gtaggttcat
     9961 ccattattaa tactttagtt tctgatgata aaactcttgc tatttctacc atttgttttt
    10021 gagctatact aagctctttg actaaactat ttggatttat atctattccc atattatcga
    10081 aaatcttttt agcctcttca ttcatttttt tgtcattggt taagactttg ccatttattt
    10141 cttttcccat aaaaatattt tgtgctactg ttaattcgtc aaaaactgtt agttcttgat
    10201 atatggcatt tatacctatc tttttagaga tatctgggga tatattctct atttctttgc
    10261 cttcaaaaat aaattttcca gaagttttcg aatgtgcacc agttaaaatc tttatcattg
    10321 ttgatttacc agcaccattt tcacccagta gtgcatgaac ttcgccatga aataactcaa
    10381 aattaacatt atctaatgct ctgacaccag gaaattcttt agcaatatta cttaacttca
    10441 gaattatatt actcataatg acactccttt ttaaatagga tttctttcaa ataatctcat
    10501 tttattttac taattcttaa agtcttttat attttcctta tcataaagta aagctggtac
    10561 tggtatattc ttttctacct tttccccttt tatagctttt actactgctt ctacagctaa
    10621 acgtcccatc tctttaggtt gttgttgaat catagcaaga atagttccat ctgttattcc
    10681 acttgatgct tcttcagtta agtcaaatcc tacaatctta acatccttat tttttgcaga
    10741 ttcaagtgca gctttagctc ctagtacact attttcagct gttgcatata ttatatctac
    10801 atctggatta gattgaatta agttttctac tgtattaaga gattcttctc tgtcatatcc
    10861 tggttgtgaa tttaatatct taacatttgc tgaacctttt aatgcatctt taaatccatc
    10921 tattctctgc atttgtattt gagattttaa atctgtcact attgctattt ctgactttcc
    10981 acctaacttt tcatctatgt attttttagt gtattcccct aattttttac cagcatcata
    11041 actaactgtt cctacataac ttgtaatatt ttcagtattt aatacagcat ctactgtaac
    11101 tactggcatt ttttcaaatg ctccttctac tgctggtact atagccgaat tatcagttcc
    11161 aagtactatc attccatcta cattttgttg tataaaatct tctattgctg atgtttgctt
    11221 agctacatct tggtctgggt catttactat aactttcaca cctaattctt tagctttttc
    11281 ttttattccc tcatcaatat ctataaaaaa ttgatgttga agagttattg tagatactcc
    11341 aatagttaaa tctttcttgt ctgaaccacc tttattatct gatttacttg gtccttccat
    11401 tgaacaccct gttaacattc ctattgctag tattccagca attcctaaag ataaaatttt
    11461 tctcactctc ataattaacc tccattttta atagttttaa atttgaacaa attagatttt
    11521 tatttattat ttaaatattt ttcaacatct tctttataag gcataccaga ttgtgcacct
    11581 agtttagtta cagacagacc tgatactact actgcatatt ctactgctgt atataaattt
    11641 ttcccttctg ttatagccac tgccaatgct ccattaaatg tatctcctgc tcctgtggta
    11701 tcttgaacat caacacttat acaagataca tgcttgattt cctcaccatc ataaaatcta
    11761 gctccatttt ttccttctgt tattacaagt ttatttggat atttttttaa tacttcttct
    11821 atcccttcat ttgtgtcaaa aactatctta tattcatgtt catttggtgt taagtaagtt
    11881 actttttcta ttatatcttc atttagtttt actgctggtg ctggatttaa taaaacccta
    11941 atcctatttt caaaacagaa attcactaca taatttattg tttttaatgg aatctctaat
    12001 tgtagcaata ctatatctgc attctttatc tcttcttcat tctttttaat taattctata
    12061 tctactagct cattagtccc tggtacaaca acaatactat tatcattttc acataatgtt
    12121 ataacagcaa caccagaact tttgtgatta tttctggata ctaagctata atcaacttta
    12181 ttcgttctaa aatttcttat taactcctct cctaagccat cttcccctat gcatgatatc
    12241 atttttacat ttgctcctag tttagaagct gagatagctt gattagcccc ttttcctcca
    12301 ggtgatgtaa aaaaactatt acctaatact gtttctcctt tttctggtct tttatctaca
    12361 gaacatacca tgtccatgtt tacacttcct atgacaacta tgtttcccat tacattactc
    12421 ctttacatat ctatttatgt ctctcgtgct gttattcact ttcttttgtt gaatctctta
    12481 tgaccaattc tggtttgaaa atcaattcat caaacgattc ttttttatct cctcttaaac
    12541 aatttatcaa tatttcactg gctttatatc ctatatcata agacggctgt tttactgtgg
    12601 taagagaagg gcttattaga cttgatgttt gaatatcatc aaatcccacg acacttatat
    12661 catttggtat acttaatcct ctttctttaa gacctcttat gacacctatt gcaatcaaat
    12721 catttgcaca aaatattgca tcaaaatcta tcttttctaa attttttata aattcttgtc
    12781 cccattcaat cttatatttt ccttcaaata cataagcagg attgtagctt aaattgcact
    12841 cgattagagc ctttttatat ccttctaatc tatctactgc tatttcattt tgaagtggac
    12901 cacttaggta tattattttc ttatttccaa tatctaataa atgttttgta gctatatagg
    12961 ccccttcaaa gttatttatt ttaacaattc cttttaaggt ttctttgttc atacttatct
    13021 tcttatcaat caagacagtt ggtattttta tatctttata atttgcttct ttccagtttg
    13081 tatttgaaga tgctgcaaat ataattccat ctatcatcct ctctgatagt gttcttattc
    13141 cttcatattc ttttttagca tcttcatctg tattacataa aattatattg tagccttctt
    13201 cattagcttt gtcttctaca cctcttgata catctgtaaa gaatggattt cgtatatctg
    13261 gtataagaag ccctatagta ttagtttttt tagttactaa actttgtgct aatttatttg
    13321 gtacataatt tttttccttc attattttca aaattttttc tcttgttgcc tgacttatat
    13381 tttcatcttt attattaatg acttttgaca cagttgtttt agaaacacca gccaattcgc
    13441 caatttcttt tatagttata ctcaagaagt tcacccccaa aatttaggaa accgttttac
    13501 ttaaccggtt acctagatac tatcacatct tttttccatt tgcaaccatt ttatataaat
    13561 tttgatattt ttcccttttt tcaaaatatt gcaacttata attcaatttt aatatttaaa
    13621 ttaatctgaa aaaaaaatta atatactttt ataattatct aaaagtatat taattaattt
    13681 aagcagtatt tattaaagtt caaatccttg ctctataatc atttttttat cattttcaat
    13741 cccacttcca acagttgtca aataatcacc aacaattgca gaatttactc ccccattaaa
    13801 tccaactttg tcatatccct ttaatgatag ccttccacca gcatacctta tgtacacatt
    13861 aggaattata aacctaaata ctgctgttgt ttttagtatt tccattggtt ctaatacatc
    13921 ataattttcc attggtgtat tcttaatagg atttaaaatg tttattggaa atgattttac
    13981 atttaattct cgtatttcaa aagccatttt tagtctctgt tcttcactct cattcattcc
    14041 aattataccg cctacacata catctagccc agctttttta gcatctttta tagtttttat
    14101 cctatcttta tatgtgtgtg ttgtacatat attatgaaaa ttatctctac acgtctcaac
    14161 attgtggtga tatgtagtca cacctgctga cttcaacatt ttagcttgct cataatctat
    14221 aatacctaaa gatgcacata attttaaatt agtattttcc ctcaatcctt catagatatt
    14281 taaaatatta ttaaactcct ttcctgacat acctttacca cttgtaacca atgagaatct
    14341 atgcactcct ttactctcca tctctttagc tctatttaag atttcattgt aatctaataa
    14401 tgaatattct tctacaccag ttttataata agaagactga gcacaaaatt tacagtcttc
    14461 actacatttg ccagatttag cattcattat cgtacataaa tctgcttttc ttcccataaa
    14521 atattctctt atttcatttg cagattttaa tagaatatca aaatcgtttt tattatttgt
    14581 atcaaggctt attaaattaa gagcttcttc ataacttatt tctttttctc tcaatacttt
    14641 attttttaat tttattatgt atttttccat atatcctcct atttgtcaac ttaatatttt
    14701 tatgtagttt acttattata tatagtattg catatataac atttattggt caactttatt
    14761 ttagacacaa gtttactata cacaaaaaaa tactgcttca aaacaatatt agtatataga
    14821 ttatacatat tattattaaa gcagtatttt ttattagaat ataattctta ctggtttata
    14881 aaactatcct tgtcttaact ccatccaagc tttccattgt aataacttct aagccttcat
    14941 attctctaaa tagccatttt aaatccttca tggcttgatt aacctgactt tttgttagat
    15001 tatttataaa atattctttt ctagtttcct catactcttt gctagtcaaa aagtttctta
    15061 gaaaattaaa cgcaaataca cttggaatat tgtttacatt agccttcttg ctgttttcct
    15121 tctcatagta aattttcata aatgcatact cctttgatac ttttagattt ctcttacaat
    15181 aattatatgc atttaagtgc tactattctt ataattttat taattcatat tctttacttc
    15241 ccatacccat ttcacatgca tagtctatta ttctagttcc atttacatga ggatgttcat
    15301 gtttgaaaac atcatgaccc atttccttac aaatcaaatc atagcatgct tgttcaatag
    15361 ctacagggtc tgttgatgct aatattccta tatcatgggc aattggtcta cctgaccaag
    15421 gtacacaatc acaaagtgga gttacattca taacaaaagt tatataccct accttgtctt
    15481 ttttatttga tactgctcca taagcgtatt ctgccatctt ttcgacaaac acatctgagt
    15541 cactttccca ttgtatagtt actgctctag ttggacagac agttggacat tctccacatc
    15601 cataacatac atcagaatct ataactgctt ttttatccac tatacttata gcttttgtag
    15661 gacaagaatt aacacacttt ccacaaccta cacacttctt ttcctttact actggagtaa
    15721 catcagaatg ttgcatttgt tttcctgctg cacttgcaca tcccatagct aagtttttta
    15781 atgctcctcc aaaacctgct gcttcatgac ctttaaaatg actcattact atcattgcag
    15841 aagaattata aatttctcca cctattttta cactttcaaa atgttttttg tctattttta
    15901 cattctcata atttctacta tataatccat ctgcaattat tactggtgca tttacaactg
    15961 cataagcaaa tccattttct atagcagttg taagatggtc tacagaattt gttctactcc
    16021 ctgtatacag tgtatttgta tctgttaaaa atggctttcc ttcgcagtct ttaaccttat
    16081 caaccacttg tctaactgcc acaggactca tatatgtagt atttcccttt tctccaaagt
    16141 gaagtttaat tgcgacttgg tcattttttt ctattaaatc tttgaatcct gcttcatcaa
    16201 ataatcttct tacattgttt ggtacgtttt tattttgcga atttgagtat aaatcacaaa
    16261 aatatacttt tgacttttcc atatctacac ccctttaaaa tatttactta tactaatttt
    16321 atcactttta aagtaatttt tagtatattt taacataatt aaatattctt atatttattt
    16381 gatacaaata atattatttg tattattttc tacacttaat tctatatatt aaactacacc
    16441 taaaaatcaa aaagacttga aacttaagtc caagtctttt tgatttttag gtgtagtttt
    16501 taacaacata agattacttt accttgtgat aaaggtatta ttaaactggt tttttattaa
    16561 ataaaataac agctgctagt aaacatacta tagaaataag aactgttata ataattggaa
    16621 taataaattc tggcattgcc actttccctg aaatcaagtc tatatttttt gacatcaaga
    16681 aattaggagt ataaggtgca atctgtttag gaatagaaat taaactcaat aagagagttg
    16741 ctaccaatac aagtaaaaca ctggcaaatg ctggtctaaa tagtacacac ccaagaatta
    16801 atacactaat atacataatt cctataagcc ataaattaaa tgctgaaaat ataatatgat
    16861 taagatttgc agttggccaa aaatacattg tatagccata agcaaataaa aaactcaacc
    16921 aaaaaccaat tgtcataata atcaccgtaa cagagaattt agacaatact atagatgaac
    16981 gtgataaacc tttagtcagc ataataacaa gtgtcccttt agaatattca tttgataaaa
    17041 tattacaaaa aataattaga gttaaactca taccaagacc agagatattg ctaaaaaatt
    17101 gtgtccaaga atctaaagca gttggtgcag cagtaacttt taaagtcggt gcaaaatgag
    17161 caatcaagtc tggcataaat tttgcagaaa taggactact tataccaaat attagaaata
    17221 aaataattaa actaaataat ttataatttc ttaaattctc tttaaattct ttttttgtaa
    17281 atgctatgta ttctctcact ttactacctc caaaaataaa ttttcaagtg ataattctat
    17341 tagttccatc tttactggac aaagattcat ttctgcgagc gtagatataa ctgttttttg
    17401 tattgctttt atatctttac catgcaaaac aatttccata ttagtttctt ctgaatcttt
    17461 tagtaaggat ttaataccat cactagactt aaacttttga atttcatcat tacttgcaaa
    17521 ctccagtaaa agtctatcct ttccgtgcat actttttatt tctgaaagtg taccactaag
    17581 ggcaatgctt cctttgttta atatagcaac atggtcacag attctttcaa catctgatag
    17641 tatatgtgtt gaaaatatta cagttgttga gtctttgatt ttaagcataa tatctaatat
    17701 ttcttttcga ccaacagggt caagtgcact tgttggttca tcacaaataa gtaatttggg
    17761 gcgtgaaagc aaagcttgag ctataccaag tcgttgcttc attccacgag aaaacccacc
    17821 tattcgtctc ttttcatttc taagacccac aagtgataac aactcttcac tccttatctg
    17881 tatttctttt tttgaaagtc ccgtaatttc accacaaaga gaaagatatt caagtggtct
    17941 catataattg taaaactctg gaacatcagg cagataacct acatgacgat tagaacttgt
    18001 tttcccatag gtcactttct caccacaaac atctatagtt ccactatctg gtttaagtaa
    18061 cccaagtacc attttcattg ttgtagtctt acctgcacca ttcttaccta caaacccaaa
    18121 gactgaccct tctggtacag taaaatttaa attatctatt atctttcgat taccaaaacc
    18181 ttttgataat ccatttattg agacaatatt catcattctt cacctcttcc tattgtaaaa
    18241 tacaaaattg gtcctattaa actaataaac agtactacaa taatccatat tgccttattt
    18301 ccaattttat aatttggatg tctcaacaca tgaacaagtg cagtaattat aagtattaaa
    18361 tctaaaataa taacaggaac caaaagtggt aagtattcca tcaaattttc cataatctta
    18421 ttcctccaat aaagataatt tttctataag aaatttgtat tctttgtttt cacttaatac
    18481 agaaaacatt ggattatttt taatagcagc aacaatacct gcttttacga ttgtatcatc
    18541 acgtgtaata cctgttccaa tttcagaaat ccatctgtca agtttattaa aaaagtcatc
    18601 cccatgtatt ataattgggt atatatcacg tgttgctaaa tctacatatt ttcgtaatga
    18661 tttaatagct ccttcattat caccatgtat taaattaatt tgtgcctgtg ttaaatatga
    18721 agaaagcata atagcaggag ataatgtatc aagctcaaat atatctgaaa ttgctagaat
    18781 acgtctttct atttccttca tttgtaattt atctgcattt tgcaaaatac ccactagatt
    18841 ttggactaat gatataaggt tctgatatgc accaagttga aatgtttctc ttgcttcatc
    18901 catttgacca ttcatcattt gcccttgtgc aagaagtata gattcattta tcatgggaaa
    18961 attgctgttt tgcaataaat caatcacttg tatgggttga tttaacaata tataacaagt
    19021 tgcctccata ctttttgctt gacggcaaat atctatgtca ttacaagttt cctgtatacg
    19081 aataaatatt tctaatgctt cactaattaa tagttcacgc tttttttcat ctacaatatc
    19141 atagtgatta actattaaaa gacccatccg aaaaatcaaa ggaaaacatg aataatattt
    19201 ttttatgatt tctcttattt catccatgac ttcatcaaat ggtttaaccg taaagtcttt
    19261 gcacagttta ttatacagtt tattaatatc ttccttcatc atttgaggtt cataacatat
    19321 taactcatca acggtaatgt tgaaatatgt cgcgagttgc ggtaaaaagg ttatgtcagg
    19381 atagctttgt ccagtttccc atttagatac agaagcttta gaaacgccta tataatttgc
    19441 aagttcatct tgtgtaattc ctttttcttt acgctttaaa atcagcgttt ttgcgatgtt
    19501 taattcattc atgtcaatcc ctccttatgt ataattatat ccttaaacat gtaaagctaa
    19561 caagcgattt gaagttgact tttgacgaaa aaatcaacca cagagaaaca aataaacaag
    19621 tatataaaat atatatttaa atttatcttt aatctccttt gtaaaatatg taaactttgt
    19681 aaataaaatc catattatat aaaactaata gttaatctat ctaaatacag tttttattta
    19741 tcacgttttt aaatattttg tgtaaaacct cttttaatat aaacacctta ttttcatttc
    19801 tcatttcata ttctttttaa aatactgaat ataactcttc gattttccat ttaatccttt
    19861 tataaagtta ttattcgtat ttattcctct aattataaca ggcaactatc atgtattggt
    19921 atttgtctat tatataaaaa tctataaaag aaaagcagtc aatcatttag attaactgct
    19981 tgtacatata tcttattaaa ctgtataaac tataattttt attattctcc attttcatcc
    20041 caagtcataa atccccatcc actatctgga taaatatcga tagacttttc tctaatcata
    20101 taaccaactt tataacactc ttttgttatt ttattagata gtatacatcc ttctccattt
    20161 atctaattcc atttaattaa cttttctttt caaccttaac ttttataaaa tcatcttttt
    20221 taataatttc atacttattt tctcttcaac atcatcaaat gagggtgtct caaaattaac
    20281 tttttacttc ataaggcact cttttttgta tgaagtaaaa tatattttca tcatttcaac
    20341 aataagtaag aggcttatct ctattttgag acagccccat ttgatggtgt tgaacattta
    20401 aataaggttg aactcgtttt atctctcttt ttaagatatc tgtaaatttg cacataaagt
    20461 ctcttcttct tttacaattc taatagtttt attaaagcca aagtatatat ctccatattc
    20521 tttcgtatat gatttattgg tactctttca tctactccat gaccaccagt tttatacgct
    20581 aagaacttag gtccaaacgc caccatatct ttaaaccaac ttgcatatgt gccaccaccc
    20641 atagcaattg tatatccatt ttcatctgtt acttcttcat aggcttctaa taatttttta
    20701 agtactaaat tactctcatc cacataatgt aagtctttat gaacaataac ctctattttc
    20761 caaccattac aaaaaacctt tttgaatcta tctattatat tgtttaaaac tatattttta
    20821 ccatacctta tatctaactc acatacgatt ttttcctcat ttacttttaa tattcctaaa
    20881 tttaaggtag tgtttttgaa tacctcatca tattgattaa tccccaatgc atctccataa
    20941 taatcactac aaaggtattt tgaaactaat tctatatctt ctctatgctg aaaatccata
    21001 ttatcctcaa ctatctttat taccatttta gatatagcat tttctccctt ttcaggatta
    21061 cttgcatgta cagctactcc tttagtagtt aactctgaaa taattccatt aataattttt
    21121 gcagtacaat gagatggaac aacattttct ttagttcctc cacttactat tatgtaaggt
    21181 ttacttttgt caattttaat ttctttttct atccttatat gaacccttcc tttttctcca
    21241 ttaaccactg gatacatagc atctggagta aatcccatac ttggaatttc ttcaccttta
    21301 tctaagtaat atttgataca tttcatacct gtctcctcat ttgtaccaaa aattaatctt
    21361 attcttttat taattgtagg atacatatcc tctatgtttt tcaatacatg tataagcata
    21421 gatacagcac ccttattatc tatgacacct cttccataaa taatattgtc aattactgct
    21481 cccgaaaatg ggtctacact ccacccctct cctggtggaa ctatatctaa atgcattgga
    21541 atccctatta attcctctcc ctctccaatt tctgcatatc caatataatt atcaatattt
    21601 ttaacactaa aacctaaact agcacagtaa tctaaagttt tatctaaaga ttttttaggt
    21661 cctataccaa aaggacattg tgaaataggt tcaccttgtt gtgaatcaat ttttatcaat
    21721 tcttttagaa attctatggt tctatttaaa ctattatcta cacttctgct tatatccata
    21781 aatcaaccta ctttctatct ttttaaagcc tgtccttaaa gaacaggctt ttagcattaa
    21841 aaattatttt tttgtaaata ctaattcaca aacttcatca tcatgagcac atttttgagc
    21901 aaaatctaat ttaacacctt gtgcacagtc aactcttcca taatccccat aacaagctaa
    21961 tctacaaatt tcttttcttt cttctttagt taatccatat tctttccaag cagcatctaa
    22021 tggacagtga tggaatttta aaacgccatt ctcatctgta ttttctacta attccatttc
    22081 aaacactttt tgtcctttac tgttatataa catttctgcc atttttcctg gagtatctgc
    22141 tacgttatat ttttgacctc tcattttacc aaatccatat attgcttctt tacatatatc
    22201 atctggatta gctcctaatt tttcagcttc tttcataaga agatagaacc atactgctct
    22261 ttctcctgtt gctcctctaa ttccttctaa atattccttt tctgtataca ttttttctga
    22321 catttctttc tcctcctaaa attaaattct atattttaat cactgtgaat tagaatattc
    22381 caatgaatga ccctaccaat gctaatacaa ccaaaattac taataactta gttattgtcc
    22441 acttcttgta tttcattccc caatatacga agaatacaac accaagtggt aataaacctg
    22501 gagcaatcat atttaatgta tcttgaacaa caattgcttt accaccaata tcaaatgata
    22561 gcggagttga aagcttaact gtagttgcag ataatgctcc catcataaac attcctagaa
    22621 ttgaagcacc atcaattatc ttattgacaa taccacctga tagaattttc ttaattgaat
    22681 ctctacctaa agaatatcct aaatgaaata agtaataacc ttcgcaaaat agtaatatac
    22741 taaacattat tgggaaaaat gcacctataa cacttccttc tgctccaaat gaagcaccta
    22801 aagctaagaa tattgtttga aatgtaccaa aatctaaagt atctccaatt ccagccaaag
    22861 gtcccataag accattctta acacctgaaa taacttctcc tgggattttt ccttcagtag
    22921 ctttctcttc ttccatagct aaaactgtac cgtgaattaa tcctccccat atagcttgag
    22981 tattaaaaaa ttgtaagtgt ctctttaacg catctactaa atcttctttt ctcttatata
    23041 acttttctaa agcaggagtg aaacttgcac aaactgctaa tgcttgcatt ctttcaaaag
    23101 agttggataa ttctgctgtc caccaccatc ttagatatgt ttttgttaca tctttctttg
    23161 taagtactct tgtcttatta acttcagttg gaccttgtcc atttttaact tctttatttt
    23221 ttatttcttg cattatactt cacctaccct tttgtcttct ttcataaagg taattaaaag
    23281 agctatacaa acaccaaata ttgcagctgc agtaattgat atttcaaaat attgaaccat
    23341 aaaaaatcct ataataaaca ttggtaagaa tttattttta cctatagtaa atattgttgt
    23401 tgcaaaacct aatgcaggta atataccgcc cattactgtt aatccattca ttaaccattg
    23461 tggtataaca tctaataatg attgaactaa atctgctcca aaaaagttac atacaaaaac
    23521 tattggaaac cttaaaacaa acccaaatat taaagaataa agtgttgcac atctccagat
    23581 gccttttgta ttaccttctt cagcatactt atctgcctta tgaaccaata cagcattacc
    23641 agttcttctt aagttattaa ctaatactcc tataacacct aaaggtaccg caatagatac
    23701 tgcaacttct gcattaacac cagtttgaag tgctactggt attgcaataa gagcagctag
    23761 acatttatct gatggaatat ttccccctgc tgcgaccatt cctagataaa ccatttctat
    23821 acttgcacca acaatcatac cagttgttac atcaccccaa agtaatccaa ggctaaaacc
    23881 tataaataaa ggagacttta gtgttgagaa aagggtatac cctgcaagac ctgctgcaaa
    23941 ccaataccat aatcctgtta caattgccaa catcaaaaca gattccattt ataattcctc
    24001 ctaatttata ttttttattt aaatttcttt aacgcatttt catatgtcat agatgattcc
    24061 tctggtataa cttgtaggac tatttcaacc ccattttcat taagttcatt aagttgttct
    24121 acatcctcat ttcctaatga aacagctgta aacaccattt tctttcctgc ttcatttgga
    24181 atacctccta attgaatctt ttcatattta agtccagctt tataagcctt atttgccata
    24241 tcaacatttt taaatagaat aaatatattt ttatctccta aagtgttgtt ttggaatgct
    24301 tgtcccgcat cttctgctgt taaaataact acttctactc ctgatggtgc tgccatttta
    24361 tatatgtcag ccataaattc atcttgacct aagaagtcat caactattat tattttttga
    24421 gcttgagcga tttttaccca ttttgttata acttgcccat gaattaatct gtggtctact
    24481 cttactaatg ttatttttgc cattatattc acctcataat ttatattttt ttaaattctt
    24541 taattaaatc cacacaaagg ttattatttt ttttgacgat tctttctggt aatgtatgta
    24601 atttatcttc tttgcttaat tcttcatcta cgattaaaat tgtctgtaag ctaagtccat
    24661 ttattgcatc tattcctctt cttatagcaa cagctattgc aacacttgat gtagatcctc
    24721 catataaatc tgatattata attttcacat cttctttatc tactacttct tcaacctctt
    24781 tcataaatac agaaacatct ttttcagaac ttagtgataa aacttcatat tgatttgaca
    24841 atccaaagtt tttatttgtt tcttctacta agacttttcc ccaagttcca tggcacagta
    24901 tgattacctt atatttattc attgctaaat aaactctcct ttatagcgat taatattttg
    24961 gtttaattct acttcttctt catcaggtac catttgaatt gatacattaa tattcttttt
    25021 aataaattca tctattaaaa gaaactcttt tttattaatg tatacatttt gagatatttt
    25081 cttttttcct attcctgtag gtattcttcc aacaataagt tttttgatat taatcccttc
    25141 ttctatcatt ctatttgcag tatctaaatt tttaattaat acaaaaacgt tatcatcagc
    25201 ttgattatta taaaaatatc tccttgattc acttacagtt aatattgata aatcaatatt
    25261 ctttggtgct gccattttta tcaaaccttt agcaataaca tcattggttg tttcatcatc
    25321 tactactact atctttttta cacctagatg cttaacccat ttatatataa cttgaccatg
    25381 tattaatcta tcatcacatc tgcaatattt tactaaagac atttttaatc aaactccttt
    25441 ttctattaca ttgagctaag aactttatta atattgttta taccagtttg tcctgcttca
    25501 atacatgctt ctgctaactc ttctaaactt tttccctctc tattaattaa agcttcaagt
    25561 agcattggaa gatttactcc agtaagtgca tgaaacttgc cacctttttt aaggtttaaa
    25621 cttgcaacat tacttggcga acctcctaat aggtcagcta atactaaaac tccgtcacct
    25681 tcatctaatt catttaactt ttctacaaaa tttttattta agtcttcaat attatcattc
    25741 ctatttagtt taattgctgc tgttctttct gctggtcctg caataagttc acagcttttt
    25801 ataatttctt cactaaaact cccatgagtc ataactatta ttcctatcac caatttcacc
    25861 tcacttttct tgtcactttt tatataagca attgccgtgc caacttatgt gtatcaataa
    25921 caaatggcta ttttacagga tttaatcaaa actttttact caattttttt taaaaactta
    25981 ttatttcgat atgtatcaaa agattttttc aacctgtatc aaatctgtat caaaaaaagt
    26041 aaaaaaaaga tagccttttg gctattttta aattttgtat caacttttga atttatctgt
    26101 atcatattgt gattcaaata tatctaatat atttgcatat tccatatctg aaataattat
    26161 atcgaatgtc tcttctacta gcttaaaact ttcttttata actaaatata attctttatt
    26221 tctactaatt ctttcttcat atgatttata aactaaagac tcttttatta ttactctttc
    26281 aatcatacat gaacaatgaa atataaactt tactaaaagt tcatcttgaa ttactaaaga
    26341 atagtgttca ctaattctat taattacttc ttttaatata aaataagcct tttccccatt
    26401 taaaaaagtc aaagttttac taatattatc aattagtaat ctatcaaaat atctaccacc
    26461 attatctttt tcagcatatg taacttccat atctccataa tgtttcttta tagattctat
    26521 aatattaaaa tataatttct ctaatgtcat ttctggagtt agagcctttc tagttgcttc
    26581 tattacaata ggtgtactta ccatatctat tgcttttact tcttttcctg tagcatcacg
    26641 aataacttta gcaaatgtta aaatagaccc catatcagtt aaaattaaaa ttccctttcc
    26701 tttatcaatt ttattggcta tttctacagc ttgtactaaa atatcctgaa ctctatcttc
    26761 taatcccata ttaattgcca ctgcatggtt acaatccagt aaagtattgg ctacattcac
    26821 catgctagat gctgtagatt caccatgcat tatgactaat attgctatac tctcctcatt
    26881 taatcccaca tacgataaat aaagaaatgt tgctaaaaaa attgcttcat cttctggaaa
    26941 ctctactcca tacattaatg acatgttaga taatatttct tttgctatgt tatattcata
    27001 tgctctttcc ttcataattt catctttatt aggatgcttt actatatttc caatctttat
    27061 tctttcaatt aaattctgaa tatgtaaagc tatagctttt attaatttat ctaatccttc
    27121 tcttttgctc catttatcat gcttttgtaa aatatatttt acagtagttg caattgaatc
    27181 attaacaatg ttgttataag ctgtttgatt actactatta tatataaaag tattcattaa
    27241 attataggaa tacttctgta tgtctccatc tataacactt ctaatttgtg actctttaat
    27301 accttcttgt tgaagtttat tccaagtttc ttttatcatt ccataaaaat ctaaatcata
    27361 ttttttattt tctattaata aattttcact ttcaaaatcc ttttcttctg gtaaaaaaat
    27421 aatatcatct tttccaataa aactgaaatt ttgtacaaac tcctcttttc tattatttcc
    27481 atataatgat tctctaatat tatttggtag aagagagagc cttacatata cacattccct
    27541 tttataggtc atataatcta aaaaagctct tgcacaaatt aattgtatat cgctttttaa
    27601 ttggcctatg tttcccttac acttatataa aataaatgcc ttaataactt cttttgaaac
    27661 ctttaactta acaccaatcc taacactctc ttctttaaaa aaataacata taagcttcat
    27721 tctctcttga aagcctcttt cctctaaaga cggaatcttt atagttacag gtattcttct
    27781 taaaaacgtt tccaacattg ctgtttctgg gtcttctgta gtggctgcaa ttatcataac
    27841 tctacactcg tgtaccttat tagcctctcc taaccttcta tatatccctt tatccataag
    27901 cagaaatagc atttcttgtc cctctgcaga taatctatga acttcatcta aaaacaatac
    27961 tccattatta gcttcatgta caataccata cttatcttta tcagctccag taaatgctcc
    28021 ttttacatat ccaaaaagct gcgctaataa taattgctga ttatcagaat aatcagcaca
    28081 gttaaatatg ataaatggtg cattatcact atcttctttt atagttaaac tatacttata
    28141 catatattct gcaaatatag atttaccaac tcctgtaggt cctattatta atgtactcaa
    28201 ccccttaggt ggatatatta ctgctgcttt agcctgttct atttgggacc ttaaacttcc
    28261 atcacatcct actaaattaa aaatattgtt ctcttttttt atactctcta aaatatactc
    28321 atctttgata gaatcatttt cactatattc gtttatagag ttaatattat caaatatccc
    28381 tttatttagt ttctttccta aaatactctc aatactttct ttatataagt actgaacagg
    28441 cttacccttt atctttataa taatactttc ttttattaat tgatttaatt ccttactagc
    28501 attacttcta tttataccta cttcagtagc tatatattct gcatcaaatc caaatctaat
    28561 gccattatta aagttcaagt gttcttctgt taaccttttc aagcaaatta aaactttttc
    28621 tttccttgat agcttctttt gtgtcatagt taacctcccc tataagcagt aatactgtta
    28681 aacatttatt attaagctta attctacaat attttaatat ttttgtctaa ttatgtaact
    28741 attgattttc tttcctattc gttttataat ataaattacg ttaccctcat cttttataga
    28801 ggaggaattt atatgaattt tttatcagat ttacacaccc actctatagt cagtggtcat
    28861 ggctatagca ctttactaga aaatattaat tattgtaaag aaaatggaat taagatacta
    28921 ggtacatctg aacatggtcc taagatgcct ggttctcccc acagatggta ctttcacaac
    28981 attcaaaata tcccaagaat cataaataac attataattt taagaggctg tgaagcaaat
    29041 atactagata ttaaaggaaa catagaccta gagccttttg taattcctcg cttagattat
    29101 cttattttgt catttcacga agctgtgttt tctccaaata cattagagaa taatactaaa
    29161 gctttaataa atgcaataaa taagcatgat aatattgaaa tattaggaca ccttggaaac
    29221 ccaaactacc caatcgacta tgaattaatc attaaattag ctatagaaaa gaatatctta
    29281 atagaaataa ataattgttc tattaaaggc gtgtcaagaa atggtagctc ggataactgt
    29341 aagtatattg ctacactttg caaaaaatat ggtgctaaaa tcatactgac ttcagatgct
    29401 cacatttgtt ttgacatagg taactatgag tattctgaaa atatcttaaa ggaaattaat
    29461 tttccagatg aattaataat gaattatcct aaaaaactta ttaatcattt tcaccaaaaa
    29521 ggtaaattac tagatgttga ttatacaaat atctaagtaa taatacatgc ttactttaac
    29581 tcccataaaa attttaatac tatttatatt atatgaaata aagaaattat aataaagaag
    29641 ctatttaata aagcttaatt acttttatga acttgatgga ttgatatggt ctatgatagc
    29701 aatagaaatt ataacatttt taataaactt agttttatat accttatagt ataaatctaa
    29761 aaaagcatca tctaaaaagg agctgtcaca tgagcaaatt aaatttgttc tatgatagct
    29821 ctttttttac ttattttaat taggtatatt tttaattatt ttatataaag cttatgttct
    29881 aagtaaaatt atgcataaca aacaaaggta taaaaat
//
LOCUS       DAJMZY010000042        29007 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.042, whole genome shotgun sequence.
ACCESSION   DAJMZY010000042 DAJMZY010000000
VERSION     DAJMZY010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 29007)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29007)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29007
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.042"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            complement(<1..394)
                     /locus_tag="OE968_001837"
     CDS             complement(<1..394)
                     /locus_tag="OE968_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCP7219118.1"
                     /translation="MLGEKMRNIRKSKKKTLSDVSKLTDLSISYISQIERDAIEPSLS
                     SLRKIAEVLDTPLYMFMDDNNTDDLVIRKEDRVMMKFPKSEMFYEIVSPMPTTEFTPS
                     ILFVEFELKPESEDAKDYIYHASEEIMVV"
     gene            746..1813
                     /locus_tag="OE968_001838"
     CDS             746..1813
                     /locus_tag="OE968_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide epimerase"
                     /protein_id="HCP7219119.1"
                     /translation="MKITDIKFEKLRIKLKKPVVVSFGVIEYGESIILKIETDEGYCG
                     FGEAAPLAAVTGEVLDNVLSVLLMFKKELIGKDPLDIETIHTIMDGIIIGNTSAKAAI
                     DIALYDIKGKIMNAPLYKVLGGFDSKVQTDITISIDKPEKMAVEALERVKEGFRILKL
                     KAGINPEDDIEAVKLIREAVGESIRIRIDANQGWNVNSSINTIKKLEEFNVDAIEQAL
                     PHWDLDGTAYIRNKSNTKIMIDESLHSPIDAIKAIKKNAVDTFNIKLMKSSGIYPAIK
                     INNIAEASGVNCMLGCMLETRIGITAAANLIASKKNITEADLDSFMFCEELEGISGGF
                     VMDGDIMNLVNKPGLGIEVNL"
     gene            1832..2992
                     /locus_tag="OE968_001839"
     CDS             1832..2992
                     /locus_tag="OE968_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF819 family protein"
                     /protein_id="HCP7219120.1"
                     /translation="MNTLFSNPGSILAVMTSMIALGFYLQRYKAIKSLGPALTIIIMG
                     IILSNLKVVPVSTELYGTISTYAIPISMTIMLMSVDLKEMTKLSREPLIAIFVAVLTV
                     SIMAFLFGLVFAEKISEGWKVAGMFVGTYTGGSANLTAIGTGLNVSRQTLAAANAADY
                     VIGVPTLIFMFALPAILKNSKKFKKLWPYHVEESELEDCQNEEFMESKEWSIKDIAWM
                     LAIGFVVTEVSTILAGYFNSSFSSAARILLVTTISIIIAQLKPVKKLKGNLDLGLFVA
                     LFFLCTIGFSVDIKEFLGSTFTITLYCFSIIFASFVFHLGITRLLKIKYQYVILSIVG
                     AIADGPTSALVAASAKWNSLVSVAVVMGVIGGVLGNYAGISVAYAIKMSLGL"
     gene            3005..5101
                     /locus_tag="OE968_001840"
     CDS             3005..5101
                     /locus_tag="OE968_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CocE/NonD family hydrolase"
                     /protein_id="HCP7219121.1"
                     /translation="MIKFKLYISGLYSGNVIFDGDLLIEKLNPFTNKIESLKPISKEE
                     NTYYLNLTKIDLKSLFNNFDVYTKSLVNTDKDTVINNLGETHSKLNEYIWVQRNKKFP
                     LDIIIVDNKIVGFICLSRETCTILIMDGYEEYTVLKEWEKTHKNEEIYSIRFGGNYMI
                     DMKDGIKLSTDVYLPDFVDSAKKAPTILMRTPYGKENDKEIYYKYVQRGYAVVIQDVR
                     GRNESEGKWEPMIHEREDGDSTINWIVSQEWSSGIVGMLGASYLGYVQWAAASSGNKH
                     LKALVSIVTSGSPFIDIPRKGGAFVSGMLAWAFMVSRNKVDRSKMVRDDWDDVLNIRP
                     IENIPVEALGYRIEFLEEWLKRVEKDEYWDLMDWHLQKDKINVPALVVSGWYDDNSMG
                     TTEALDVIKDYEKGKRKAILGPWMHNSNTLRDINGISLGNSSLRYDLDYNYLLWFDKY
                     LKGIENNIDTTAPVEYYSVGSNKWKTEENWPIINKIDKSMYLISDGNANTSLGNGRLV
                     FDNDLEEKYDSYIYNPKDPSVQLIDMSENEVGVPNNYKDLEKRSDMLCYTSDAFSEEF
                     TVTGDIKLEFFASSSAKDTDWVIKIMDVDLDGNSIKLADGILSARFRNSFYKSEFMEE
                     GEIYKFTIITSKISNTFKVGHKIRLDITSSAKNFIFQNSNTTEGYNSIEYIEAKNTIY
                     HGGKYPSKLILPIENK"
     gene            complement(5260..5604)
                     /locus_tag="OE968_001841"
     CDS             complement(5260..5604)
                     /locus_tag="OE968_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HCP7219122.1"
                     /translation="MEIKRYEGTGRMSRAVVHNNTVYLCGQTHAEGGVIEQTTEVLAK
                     IEDLLNKYGSDKQHLLSVTIYLRDMKDFEAMNSVWDAWVEKGFEPARACVEARLAREH
                     LLVEMSVVAATK"
     gene            5896..6786
                     /locus_tag="OE968_001842"
     CDS             5896..6786
                     /locus_tag="OE968_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HCP7219123.1"
                     /translation="MSSTIKSNRIKGIMFIIASALGFAMMSAFVKLAGDLPSFQKVFF
                     RNLVSAIIAFWLIIKHKGSLTGKKENLKVLLYRSIFGTLGVIFNYYAIDKLMLSDANM
                     LNKMSPFLVVIFCAIALKEKINVKQIGAIIIAFIGALFIIKPTFSVEVIPYLGGIAGA
                     VFAAMAYTCLRVLGDREDYYTIVFFFSVFSLVTVGPIAFAVYEPMTLMQLIYLLLGGV
                     FASLGQFGITLAYKYAPAKEISIFDYSNIIFSAILSIFLFNVYPDMLSVVGYLIVFSA
                     AFYMFLYNKKLDKLDKEKKK"
     gene            7004..8290
                     /locus_tag="OE968_001843"
     CDS             7004..8290
                     /locus_tag="OE968_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HCP7219124.1"
                     /translation="MEKVKVAVIGAGNRGTYAYAPYIYENSDVCEIVAVAEPKKGRRE
                     LFTQKYNLDSKNVFETLEDFFKHDKMADAVIIATNDDRHYDVAKLALEKGYHVLLEKP
                     MSNSLDGLVHIDDLCDKYKDKIFMICHVLRYSPFYNKLKEIVESKKLGELVSIQYNEN
                     IGYWHFAHSFTRGNWRNSNETSPLILAKSCHDMDILLYLVGSRCKKISAFGSLKHLNN
                     QNASGEMAQNCLQCLVEKKCPYSAKRIYLEKDRSINRAVHINPTEENLLNILKTSPYG
                     RCVYRCDNNVVDNMVNILQFENGVTATFNLCAFTKENGRTIKLMFSHGEVGGDLNKNE
                     IRIKEFGKNEEIVMNPSNQQNMVEEYDRNLIAEFIKLVSNKELEKGRVAAKEAIQSHV
                     MAFAAEYSRVSDEVVYIEEFFDSAKQMTKEIEETIF"
     gene            complement(8379..8822)
                     /locus_tag="OE968_001844"
     CDS             complement(8379..8822)
                     /locus_tag="OE968_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="regulatory YrvL family protein"
                     /protein_id="HCP7219125.1"
                     /translation="MIKISNKRRIPLGEFISVFLFFAVFFGITFCIFTVIGIGFLSFL
                     GFEYKSLGAVLIFFLIYFCITTPIDFLCTTILDIFRYVNKLPYSIYKLCEFIIDFILT
                     FLAMNIIDTFMDSVTIPLSTEILFALLSYLLSECMDFFDRDKKKP"
     gene            complement(8846..9640)
                     /locus_tag="OE968_001845"
     CDS             complement(8846..9640)
                     /locus_tag="OE968_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M55 family metallopeptidase"
                     /protein_id="HCP7219126.1"
                     /translation="MKLYLSADIEGTCGIVNWDETKLECEFSQHYRTQMSKEITAACD
                     GATQSGVHEILVKDAHDSGRNINPNILPENVKILRGWTKDPLVMMAGIDESFDACIFT
                     GYHSGATCNGNPLSHTMDIDYDYFKINDEIASEFTINAYIAAYYNVPVAFLSGDEMLC
                     ESAKKLNPNIVTVPVSKGIGNGSISIHPNLALKKIEKGVKKALSGDLSRHLIKLPDKF
                     KIEIKFREHYKAFKASFYPNMKKIDSQTVLFETEDYYEFLRMLLFI"
     gene            complement(10206..10682)
                     /locus_tag="OE968_001846"
     CDS             complement(10206..10682)
                     /locus_tag="OE968_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase"
                     /protein_id="HCP7219127.1"
                     /translation="MKEILINPIGKICIQGEEVFIKLDKKYVPALNELDDFSHLNVFW
                     WADGFDNPELRSILETPKPYKSGPDVIGIFATRSPIRPNPIALTAVQIINIDHENGII
                     KIPYIDANDNSPVIDLKPYTPSVDRVENPSVPKWCSHWPKSVEKSGEFNWEDEIEF"
     gene            complement(10783..11952)
                     /locus_tag="OE968_001847"
     CDS             complement(10783..11952)
                     /locus_tag="OE968_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HCP7219128.1"
                     /translation="MLNIKTLCHEINDWVINIRRDLHKTPELGLEEFQTKKKIIKYLN
                     EIGINYIEYKNHTGITAYINVSPNFETVAIRADIDALPITEELNYSYKSINIGKMHAC
                     GHDAHTAILLGTCNILFKLKDYLNVNVKFFFQPAEETIGGAQLMIEDGCLEKPNVKYI
                     FGLHVNPNINKNLIELKYNTLNASTNTLQLTVHGSKCHGAYPHQGIDAIVISAHIITA
                     LQTIVSRNTNPTDSVVISLGKIEGGIKENIVCDKVVIRGTLRTLTPETREFSKKRIRE
                     ICDFTCKTFGGSISVEIEEGYPALINSNHLVDYVKQNAVELFGEENIILKDSPTLGAE
                     DFSYFLRHCEGAFYHLGCANREKNITSPLHTSTFDIDEDCLITGVMLHVKNVLSF"
     gene            12115..12978
                     /locus_tag="OE968_001848"
     CDS             12115..12978
                     /locus_tag="OE968_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HCP7219129.1"
                     /translation="MLGIIAPSGPLRNTSLEEIKFNLESYGYEVKFSESCSLNYKGYL
                     AGNDDIRARDIEDMFLDKDVDIIMCLRGGYGTTRILDKINYDIIKQNPKPFIGFSDIT
                     GLNLAFYKNCGLLPYHGIMAANVGKWGKFTYKSLVNALEFKDELYLENPKEEKIYTVC
                     EGKAEGIIMGGNLSLIIATMGTKYEIDAKDKILFIEEIGEPQYKLDRMLTQLYSSGKL
                     EECNGIIFGDFKDCIEENDLMELLIEFANKVNKPSIYNLQSGHCIPMITIPLGRMCEL
                     DATEKIVKLKK"
     gene            13049..13642
                     /locus_tag="OE968_001849"
     CDS             13049..13642
                     /locus_tag="OE968_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3867 domain-containing protein"
                     /protein_id="HCP7219130.1"
                     /translation="MSDDRIIDFNELKNKVKDSDVDKFEQYIYNLYFSVMDGKMSMAE
                     FSRKIFDYMRDNNISQEKFMKIQKQFMERYGMDTEEVEKQLRNFGIDPSTAGFMSNNT
                     SSKVSTEDLESFKKSAGFYEKYGEKIQPKSCITTFIKNDLNDINVIIDQEKIMLCSDR
                     KINLMDSELNEFLLEYKNMFNKKIKVVMCETTNKYDY"
     gene            complement(13893..14528)
                     /locus_tag="OE968_001850"
     CDS             complement(13893..14528)
                     /locus_tag="OE968_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HCP7219131.1"
                     /translation="MDNLLNELEALKSNLDNLPIEKIENYDLSKTALFIIDVNNGFAR
                     QGALYSPRVESLIKPIEMFTKKISNKLNRVIAFTDSHTPKSIELLSYPVHCLENDVES
                     ELVDELKSIENLQILPKNSTNGFFALENLDFDNIDNIIIVGDCTDICIYQFAITLKSY
                     FNQHNIEKNIVVPMNLVDTYDIPNVHPAEILNLVFFNSMIQNGVNVLKEIR"
     gene            complement(14608..15339)
                     /locus_tag="OE968_001851"
     CDS             complement(14608..15339)
                     /locus_tag="OE968_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HCP7219132.1"
                     /translation="MNIYAHRGFSGKYPENTILAFKKCLDMDIYGIELDVHRTKDGKI
                     VVIHDEKVDRTFNGHGFVKDFTLRKLKTLNSSFEGYQSNKECKIPTLEEVLILISPTD
                     LILNIELKTDKINYPNIEKDVLELILKYNMKNRVLISSFNSNSLKNFHKLDPSIKTGL
                     LCYLPINNVVNFAKFLGNSYLHPPLVLVNESLIELCHKNLLGVNVYTVNEEGDILHCL
                     KLNVDGIFTNYPDIASNLLHSKQYS"
     gene            15670..17859
                     /locus_tag="OE968_001852"
     CDS             15670..17859
                     /locus_tag="OE968_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid adenylation domain-containing
                     protein"
                     /protein_id="HCP7219133.1"
                     /translation="MYEVNLERAMNYWMDLLDDYTNIAKIPNDFFYKDCSDEVVDEVF
                     KMNIEKHERLIQYSKVNNISIDSIIETIYGLILQKYIYEDDVVFGKTMNIIPIRVRVR
                     QSEKFIDVVRKLKRQWSRSLEYGYYLLSDIENKNHLNTKLINTIFIAKSFDLSYDYDI
                     EKKGYDLSVIVYTKRALKIKIKYKPSIYKRETIRRILNQFDYIIEQIIEDNDILIEDL
                     EFVCKEEEKVLLEDFNNNQYEIPYDKSYVDLFREQVKVTPSNIAARDENRKLTYKELD
                     EVTDKLAGYLNHIGVESEDIVAVMLPRDINIIITAIGIMKSGGAFFPIDTSNPEERLN
                     YLLEDSNAKVVITTDELKSKVVNENTIVLDINDEEMFKLGYELTEKITSSNCAYTIST
                     SGSTGRPKTIAIEHKSLVNMCYYSVKSISATENDICGIYLSFSFDAVMKQLFPYLLVG
                     ASIDIMPEEAKFDEYTVNEYCEENDITILALPTAFARLFIQNCNNNSLRVVQTGGERL
                     KGYRKRNYELYNEYGPTEFTVVSTSFHVDREYGKIPIGKPIFNTYAYVLDKKNKLCPI
                     GAPGELCLSGIQISRGYLNKKGLTEQVFVENPYKTCEHNKLMYRTGDLVRWLDDGNLD
                     YIGRMDNQVKIDEFRIELYEIENIINNITEIKSVVCISRTNDDGDMYICAYYVIDEED
                     SGKINERTIREYLNEHLPPYMIPTIIMRIDKIPVTPIGKVNKRALPE"
     gene            18270..20198
                     /locus_tag="OE968_001853"
     CDS             18270..20198
                     /locus_tag="OE968_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide transporter, OPT family"
                     /protein_id="HCP7219134.1"
                     /translation="MNKKLPKGAYGEVSGKDYVPYITDKSRTGGNVAVLIIGIILAAI
                     FAASTTYSGMKAGLTVAAGIPGAIIGSAFVGAFARSKGILGKNLIQGMSSGGESVASG
                     FIFVLPAVILIGSQITFFEGLAVGVGGVLFGIGIAAIVHNYLIVEEHGKLMYPESMAI
                     SETLVASEAGGDSIKYMGIGFVISGFITVLTGSFLNVANNVMSLVGSKFYKWKFDIEV
                     NPLLLGIGFIVGLEVSLTMFAGSILSNFGIAPLIGYFTDMAKDGAMVWNNPAMPLNQM
                     DVGAISSSYVKYIGAGMMLCGGIIGAIKLIPTIIASIKETLKAKSSAGEGEEGSSIQM
                     ILLLGGVVIGFLAAFLISGNIVMAIIGAIISLLLSLLFVIVAGRLTGTIGTSNLPVSG
                     MTIASLVIVTLVFVIMGWTDLEANKSLLLFGSFIVVAIAIAGGYTQSQKVTYIIGGSK
                     NEMQRYFTIASIVGVIVVVGVILLLSDQLRATGDNVQFALPQANLMSTLTSGIMSGSL
                     PWVMIIVGVFMAIVLYALNLPIMTIAIGFYLPIATTSIILVGALIRLFVELVSKTEKE
                     KEVKVSNGISLSSGLVAGGSIIGLIGIILQVTGVVTPKVPSGFAATNSMAIALLVVLV
                     VLTALPIVLSKVKNNEQE"
     gene            20185..20532
                     /locus_tag="OE968_001854"
     CDS             20185..20532
                     /locus_tag="OE968_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PqqD family protein"
                     /protein_id="HCP7219135.1"
                     /translation="MSKSNDVLDIVFKITDGLEYEVAENRVVTILEKQDHKIQKFFRK
                     LKARIPKYKKIELDEYSSFVFLQIDGQRTVREIGKNLEAKYGEESHPLYERLLVFLNH
                     IEVNCHYIERLDI"
     gene            complement(20774..22693)
                     /locus_tag="OE968_001855"
     CDS             complement(20774..22693)
                     /locus_tag="OE968_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_071223118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HCP7219136.1"
                     /translation="MNLMTLENISKSYSEKKLLENISLGINEGEKIGLIGVNGTGKST
                     LLKIIAGVEESETGNITKTNGIRIEYLPQNPTYNENSTVLEQVFNGTSEELKLLGEYQ
                     EILEKLNSNFTEELNKKLLSVHEKIDALNLWDLESEAKSVLTKLGINDFNQKIAELSG
                     GQRKRVSLASALITPCEFLILDEPTNHLDNDTIDWLEEYLNSRKGSLLMITHDRYFLD
                     RVTNRIIELDKGRLFSYDGNYSIFLEKKMERLSLEASIEDKRQNLIRTELAWVRRGAQ
                     ARSTKQKARLQRFDELINRDSFKPDENLDISVASSRLGNKIIEIHNISKSFEENTVID
                     NLEYTLTRTDRIGIIGKNGMGKSTLINILNGEIEPDSGYISIGETVKIGCFSQDDSHM
                     NIDMRAIDYVKEASDYIETSDGTRITASQMCERFLFNGTMQYTLIGKLSGGERRRLHL
                     LKILMTAPNVLLLDEPTNDLDIETLKILEEYLDEFKGVVVTVSHDRYFLDRICNKIFA
                     YEGNGKIHIYTGNYSDYLIYREIQGIEFEESKKESVKKDDSTTLKKEKPKNDKKLKFS
                     YNEQREFENIDSDIEKLESKIATLDESTAKFSTDFTKLQEILDEKSKLEKELEYKYER
                     WEYLNNLADEIANNK"
     gene            complement(22719..23525)
                     /locus_tag="OE968_001856"
     CDS             complement(22719..23525)
                     /locus_tag="OE968_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HCP7219137.1"
                     /translation="MNLILGDNMSKKSKRRKINKLKLTIVITVLFLALLSIYEILFSN
                     PNKKGNIKSQETMQNKNNTTDDSKNNQSSTKKQEDNNIKPTFSYSSIPDNIKNKMIGK
                     SMPTDEPISFDSLSYLKLTYYGFDEKTHQGEMIVNSELAPEVVDIFKELYEKKYPIEK
                     IKLIDDYDAVDEKSMSDNNTSSFCYRTIAGTNVVSNHGKGRAIDINPLQNPQVSGNDV
                     TPKVSTVYADRSSTKFGMIKKGDDCYNAFVSRGWSWGGYWKNPDYQHFEK"
     gene            complement(23584..25032)
                     /gene="ddlR"
                     /locus_tag="OE968_001857"
     CDS             complement(23584..25032)
                     /gene="ddlR"
                     /locus_tag="OE968_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator DdlR"
                     /protein_id="HCP7219138.1"
                     /translation="MIFSNLKLNDNEPIYIQLKNYISDMISKGLIPDNSKLPSTRELS
                     QLLQVSRNSVVLTYEELKSEGLIYSISGKGTFVKSKNKSSNTTWSLNWDCLENTYSKK
                     ANELDIIKSEIPWSSDLISFKSISPDGDLFDIEELKKSFLNRISLEGHKLLNYGYAQG
                     YKPLIDYLLEYMTNKGADISNKDILITNGFTEGFDIIMSSFTQEKDYIICENPTHNTA
                     IKIMKSHNLNILGVDINEDGLDFNMLEDNLVKYKNKIKFAYITPSYHNPTGIVMTPEN
                     RYKFYNLMKKYNIAIIEDGFNEELLYNSSHIFPICSLDNMNNGVVYIGSFSKILFPGM
                     RIGWIFADKKVINKLESVKRCRNIHVSFLDQGILFDYLSNGGFEKYIKKIRKFYGDKF
                     NFAYKCIKKYIKTEYILGDGGLHIFIKLKNIDTRVLLEKCYEKNVIFMPGDLFFTDNS
                     GFDTLRLGFSRLSFEDIEIGIKIIGETINEMF"
     gene            complement(25056..25955)
                     /locus_tag="OE968_001858"
     CDS             complement(25056..25955)
                     /locus_tag="OE968_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HCP7219139.1"
                     /translation="MKIAVIMGGISSEREVSLNSGKEIYNNLDKNKYEVVKVIIDDKK
                     DIFTKIPEDIDFAILALHGKFGEDGCIQSILETMDIPYSGCGPLCSGMCMDKNITKKM
                     LRDSNLPTAPWVLVKSVDEIDYDEIDNIGYPVFIKPNSGGSSVATFFIHSKDEVEEAV
                     RKGLEVDEFVMIEKYIPGGEYTSFILNGEVFPTISIKSDSGFFDYEAKYSVEKGAKEE
                     VVYLDEELQKRVNEISETCWKIFNCKAYVRVDMIISEGIPYVLELNTLPGMTQTSLIP
                     RSAAARGIKYSELLDKLIEYSLN"
     gene            26213..27469
                     /locus_tag="OE968_001859"
     CDS             26213..27469
                     /locus_tag="OE968_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011591286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HCP7219140.1"
                     /translation="MKAEIISVGTEILLGDIVNTNSQFLAKELASLGIEVYHQSTVGD
                     NKQRLLECFDESLKRSDFVITTGGLGPTGDDMTKETAAEYFGQKLELHKPSLEVLESF
                     FVKTGKKMAENNMKQVYFPKDAIVLKNNNGTAPGAILKKDGKFIIVLPGPPREMKAMF
                     NESVKPYLQQFTNEMLVSKTLRLYGIGESNLELEILDIINEQTNPTVALYAKELEVTI
                     RITAKAENEREAFKLIKPVEEKIKSRVGKYVYTEGDISISEGETALEDAVSKLLVEKN
                     LTIAVAESCTGGLVSSSLINYPGISSVFLEGCVTYSNDSKMKRLGVKRETLEEFGAVS
                     EQTAIEMAEGVAKGLKANIGISTTGVAGPGGGTKEKPVGLVYTAIYINGKTIVKKNIF
                     NGDRRKIRLRATRDLLNELRIQLEKL"
     gene            27527..28306
                     /locus_tag="OE968_001860"
     CDS             27527..28306
                     /locus_tag="OE968_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HCP7219141.1"
                     /translation="MIKHIFCDLDGTLYENGTITKEDIVAIEEIEKKGVQFNVATGRI
                     FKQAHNIIKDSLDMNGYYVCENGSFIYDKDYNVIFKRTIDDNLVKKVIDRFESSDAQL
                     YFKYKGDVIVGSDTTAFRHYSSDFIVDPDFEKRSSFDNLIGNIGVCSENLEELSRIEL
                     YLKSEFSEVLEIYFSGTYTLNIVPKSVSKRGSIEHVIKTLNVSPDEVATIGDSPNDIC
                     MLEGFKYSFAMSKAREDVKQSANYVVDSVKSAIDVIMEINS"
     gene            complement(28410..28994)
                     /locus_tag="OE968_001861"
     CDS             complement(28410..28994)
                     /locus_tag="OE968_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc dependent phospholipase C family protein"
                     /protein_id="HCP7219142.1"
                     /translation="MLMNTHFIMAKSILDNIDENKTFFISEKNFIYGNIKPDAFSKYK
                     LKKHYLDESFNMIVSKINYLCSLNIDSLSKYFSVSRLSQELGVICHFLCDFFCVAHSE
                     RWEFKHSLNKHVTYERELGAFAKDVDLSKIKCGTINSSFEKFFTKLYSDYKKKTDYMN
                     DLKFSAYTCNSVINYILDSILSNTIKSYHIANCG"
BASE COUNT        10670 a         3581 c         4543 g        10213 t
ORIGIN      
        1 ttaccaccat aatttcttct gatgcatgat atatataatc tttggcatcc tcactttctg
       61 gtttaagttc aaactctaca aataaaattg aaggtgtaaa ctcagttgta ggcattggag
      121 atactatctc gtaaaacatt tcactctttg gaaatttcat cataactcta tcttcttttc
      181 taatgactaa atcatcagta ttattgtcat ccataaacat atataaagga gtgtctaaaa
      241 cttcagcgat ttttctcaat gaagacaagg atggttcaat agcatctctt tctatttgag
      301 agatataact tatagataaa tctgtcaatt tggaaacatc acttaatgtt tttttcttgc
      361 tttttcttat atttctcatc ttttcaccta gcataagaac ctccaaataa taaaattaat
      421 ataaaatatt cgcttaaaac aaagtaatta tagcacaaca tagaagtagt ggcaataaga
      481 atacatagta gattttgaca attaaaattt aattaaatcc aaataaaagt ctatgaaaat
      541 gaattattgt taaattaata caaagaaaat aataataaaa aaatttaata gaagagtatt
      601 aattgaatta agattatcac attatatttt ggaaaagagt aaattttcag taaattatct
      661 tgacatatat attgaagtaa taatataatt taaagtataa aattttaaaa attgaattat
      721 aacttcaaaa aataaggagg gtaatatgaa gataacagat atcaaatttg aaaagcttag
      781 aattaaatta aaaaaacctg tagtagtttc atttggagta attgagtatg gagaaagtat
      841 aattttaaaa attgaaactg atgaagggta ttgtggattt ggcgaagcag cacctcttgc
      901 agcagttaca ggtgaagttt tggataatgt tctttcagta ttgcttatgt ttaaaaaaga
      961 gttaataggc aaagacccac tagatattga aaccatacat accatcatgg atggaattat
     1021 tataggtaat acttctgcaa aagcagctat tgacatagct ttatatgata ttaaaggaaa
     1081 aattatgaat gcacctcttt ataaagttct tggaggattt gatagtaaag tccaaacgga
     1141 tattactata agtatagata agccagaaaa aatggcagta gaagctttag aaagagtaaa
     1201 agaaggtttt aggatattga agcttaaagc aggtataaat cctgaagacg atattgaagc
     1261 tgtaaagtta attagagaag ccgttggaga gagtataaga attagaattg atgcaaatca
     1321 aggatggaac gtaaatagca gtataaatac tatcaaaaag ttagaagaat ttaatgttga
     1381 tgcaattgaa caagcacttc cacattggga tttagatggt actgcttaca taagaaataa
     1441 aagtaacaca aaaattatga tagatgaatc attacattca ccaatagatg caattaaggc
     1501 tataaaaaag aatgcagttg atacatttaa tattaagctg atgaaatcaa gtggaatata
     1561 tcctgctata aaaatcaaca acatagctga ggcaagtgga gtaaattgta tgttaggatg
     1621 tatgctggaa acgagaattg gtataacagc agcagcaaat ttaatagcat ctaaaaagaa
     1681 cataacagaa gctgaccttg atagttttat gttttgtgaa gaattagaag gtatatctgg
     1741 aggatttgta atggatggag atattatgaa tcttgtcaat aaaccaggtt taggaataga
     1801 agtaaactta tgataaattt ggaggttaaa tatgaataca cttttttcaa atccaggtag
     1861 tatacttgct gtaatgacat caatgattgc attgggtttt tacttacaaa gatacaaagc
     1921 cattaaaagc ttaggaccag cacttacaat aatcataatg ggaataatac tttcaaactt
     1981 aaaagtagtt ccagtaagta ctgagttata tggaactatt tcaacatatg ctattccaat
     2041 ttctatgact ataatgttga tgagtgttga cttaaaagaa atgacaaaat tatcaagaga
     2101 acctttaatt gcaatttttg tagctgtatt aactgtaagt atcatggcat ttttatttgg
     2161 attagtattt gcagaaaaaa tatcagaagg ttggaaggtt gctggaatgt ttgtaggtac
     2221 atatactggt ggaagtgcta atcttacagc tattggaaca ggtcttaatg taagtagaca
     2281 aactcttgca gcagcaaatg cagcagacta tgtaattgga gtaccaacat tgatatttat
     2341 gtttgctcta ccagcaatat taaaaaattc aaagaagttt aaaaaacttt ggccatatca
     2401 tgtagaagaa tcagaattag aagattgtca aaatgaagaa tttatggagt caaaagaatg
     2461 gagtattaaa gatatagctt ggatgttggc tataggtttt gttgttacag aagtttcaac
     2521 aatacttgct ggatatttca attcaagttt tagtagtgca gcaagaatac ttttagttac
     2581 aacaatttca attataattg ctcaattaaa gccagtaaag aaactaaagg gaaatttaga
     2641 tttaggatta tttgttgcat tattcttttt atgtacaata ggtttttcag tagatataaa
     2701 agagttttta ggttcaactt ttactataac actttactgt tttagtataa tttttgcttc
     2761 atttgttttc catttaggca taactagact tttaaagata aagtatcaat atgtaatact
     2821 ttctatagta ggagcaattg ctgatggtcc tacttcagct ttagtagctg cttctgcaaa
     2881 gtggaattcg cttgtaagtg tagcagtcgt aatgggagta attggtggag tattaggaaa
     2941 ttatgcaggt atatcagtgg catatgcaat aaagatgtct ctaggattat aggggggagt
     3001 ttaattgata aaatttaaat tatacatatc tggactatac agtggaaatg taatctttga
     3061 tggagattta ttaattgaaa agttgaatcc ttttacaaat aaaatagaaa gtttaaaacc
     3121 aataagcaaa gaagaaaata catattattt aaatcttaca aaaatagatt taaagtcttt
     3181 atttaataat tttgatgtat atactaaaag cttagtaaac acagataaag acacagttat
     3241 aaataactta ggagaaacgc attctaaact taatgaatat atatgggttc aaagaaacaa
     3301 aaagttccca ctagatataa ttattgtaga taataaaata gtaggtttta tctgtttatc
     3361 tagagaaact tgtactatat taattatgga tggatatgaa gagtatactg tattaaaaga
     3421 atgggaaaaa actcataaaa atgaagagat atattctata agatttggtg gaaattatat
     3481 gattgatatg aaagatggta taaaactttc tacagatgta tatctccctg attttgtaga
     3541 ttctgccaaa aaagcaccga caattcttat gagaactcca tatggaaaag aaaatgataa
     3601 agaaatatat tataaatatg tacaaagagg atatgctgtt gtaatacaag atgttagggg
     3661 aagaaatgaa tcagaaggta agtgggaacc tatgattcat gagagggaag atggagatag
     3721 taccataaat tggatagtat cacaggaatg gtcaagtgga atagttggaa tgcttggagc
     3781 atcatatctt ggttatgtcc aatgggcagc tgcatcttca ggcaataagc atcttaaagc
     3841 tttagttagt atagtaacat caggaagccc ttttattgat ataccaagaa aaggaggagc
     3901 ttttgtatct ggtatgcttg catgggcatt tatggtatca agaaataaag ttgatagaag
     3961 caaaatggta agagatgatt gggatgatgt tttaaacata cgaccaatag aaaatatacc
     4021 tgttgaagct cttggatata gaattgaatt tctggaagaa tggttaaaga gagtagaaaa
     4081 agatgagtat tgggatttga tggactggca tttacaaaaa gataaaataa atgtacctgc
     4141 attggttgta tctgggtggt atgatgataa tagtatggga actacagagg ccttagatgt
     4201 tataaaggac tatgaaaaag gaaagagaaa ggctattcta ggtccatgga tgcataattc
     4261 aaatacttta agagatataa atggtatttc tttaggaaat agttcattaa gatatgattt
     4321 ggattataat tatctattat ggtttgataa atacttaaaa ggtatagaaa ataacataga
     4381 tacgactgct ccagtagagt attactctgt aggttctaat aagtggaaga cagaagaaaa
     4441 ttggccaata ataaataaga tagataaaag tatgtatcta ataagtgatg gaaatgctaa
     4501 cacatcttta ggaaatggta gattagtatt tgataatgat ttagaagaaa agtatgatag
     4561 ttatatatat aatccaaaag acccatcagt acaactaatt gatatgtcag agaatgaagt
     4621 tggagttcca aataactaca aagatttaga aaaaagaagt gatatgttgt gttatacatc
     4681 agatgctttt agtgaagaat ttactgtaac aggtgatata aagttagagt tttttgcatc
     4741 aagttctgcc aaagatactg actgggttat aaaaattatg gacgtggatt tagatggaaa
     4801 ttcaattaaa ttagctgatg gtatacttag tgctagattt agaaatagtt tttataagtc
     4861 agagtttatg gaagaaggag agatttataa gtttacgatt ataacttcaa aaatatcaaa
     4921 cacgtttaaa gttggtcata aaattagact agatataacg tctagtgcta aaaactttat
     4981 tttccaaaat agcaacacga cagagggata taatagtatt gaatatatag aagcaaagaa
     5041 tacgatttac catggaggta aatatccatc taaattgata ttgccaatag agaataagta
     5101 aatttatata gattaaatag tgaggaggtg tctcaaaatg aattttttag ttcgtgagac
     5161 actttctttt atacgaaatc aaatatattt tcatcatttc aacaatgaaa aagaggctta
     5221 tctctctgtt ttgagatagc ctcctataag ctaaattgat tattttgtag ctgcaacaac
     5281 gctcatttca actaacaaat gctctctagc aagtctagct tcaacacaag ctctagcagg
     5341 ttcaaatcct ttttcaaccc aagcatccca aacagagttc atagcttcaa agtctttcat
     5401 atctcttaaa taaatagtaa cagatagcaa atgttgctta tctgaaccat atttgtttaa
     5461 taaatcttct attttagcta aaacttcagt tgtttgttca attactcctc cttcagcatg
     5521 agtttgtcca cataaataaa ctgtattgtt atgaactaca gctctactca ttcttccagt
     5581 tccttcatat ctctttattt ccatatttta aatacctcca tagttaaaaa atctattaaa
     5641 aatctaaata ataaattaaa aaaagtctat actatataaa attatattat atattctgat
     5701 aataatccat aaaaacatat aactttttag ctataattat tattgttatt aattgaaaag
     5761 atttattagt tacttgacat agtttacact tttaattata gtataaattg gaatatttag
     5821 ataattatta tttaatgtat aagctaagtt tttaattaat atggctttat acatttatat
     5881 agaaaagagg tacgtatgag tagcacaatc aaatcaaatc gaataaaagg tataatgttt
     5941 ataatagcat cagcgcttgg ctttgcaatg atgtctgcat tcgtaaagct agctggagat
     6001 ttaccaagtt ttcaaaaagt gttctttaga aatctggtat cagctataat agctttttgg
     6061 cttatcataa aacataaagg aagtctaact ggtaaaaaag aaaatttaaa agtactttta
     6121 tataggtcaa tatttggaac tctaggagtt atatttaact actatgcaat tgacaagttg
     6181 atgctttcag atgctaatat gctaaataaa atgagtccct tccttgtagt aatattttgt
     6241 gcaattgctc taaaagaaaa aataaatgta aagcagatag gagctattat aattgcattt
     6301 ataggagctt tattcataat aaaaccaaca tttagtgtag aagtaattcc atatcttgga
     6361 ggaattgcag gagctgtatt tgcagcaatg gcatatactt gtttaagagt tcttggagat
     6421 agagaagatt actatacaat tgtatttttc ttttcagttt tttcattagt tactgtaggg
     6481 ccaattgctt ttgcagtata tgaaccaatg acccttatgc aacttatata tctattacta
     6541 ggtggagtat ttgcaagtct aggtcaattt ggaataactc tagcatataa atatgcacct
     6601 gctaaggaaa tctctatatt tgactatagt aatataatct tttcagcaat tttaagtata
     6661 ttcttattca atgtctatcc agatatgtta agtgttgttg gatatttaat agtattttcg
     6721 gcagcatttt atatgttttt atacaataag aagttagata aattagacaa agaaaagaag
     6781 aagtaaacta gataaaagtg tttttataat ttgtatttaa tatttaagtc tttgtattaa
     6841 aattaaagaa aatttaatta aaaatgtttg gtatattaac ttataacagc agttaaaatt
     6901 gaaaaattat aactgctgtt tcttttatta aaaatatcca aatgtctgta aaaatagact
     6961 ataatagagt agtataaata atataaaggg gataaattaa agtatggaaa aagtgaaagt
     7021 tgctgtgatt ggagcaggta atagaggaac gtatgcatat gctccatata tttatgaaaa
     7081 ttctgatgta tgtgaaatag ttgctgtagc agaacctaaa aaaggaagac gagaactatt
     7141 tacacaaaaa tataacctag atagtaaaaa tgtatttgaa actttagaag acttttttaa
     7201 acatgacaag atggcagatg cagtaataat agctacaaat gatgatagac attatgatgt
     7261 agcaaaacta gctcttgaaa aaggttatca tgtactatta gaaaagccaa tgtctaatag
     7321 tttagatggt ctggtacata tagatgactt gtgtgataag tataaagata agatttttat
     7381 gatttgccat gtactgagat attctccatt ttataataaa ttaaaagaaa ttgtagaaag
     7441 caaaaaatta ggagagctag ttagtataca atataatgaa aatataggat attggcattt
     7501 tgcacatagc tttactagag ggaattggag aaatagcaat gaaaccagcc ctttaatttt
     7561 agcaaagagt tgtcatgaca tggatatttt gttatattta gtaggaagta gatgcaaaaa
     7621 aatatctgca tttggaagct taaagcatct taataaccaa aatgctagtg gagagatggc
     7681 acaaaattgt cttcagtgtt tagttgaaaa aaaatgtcca tattcagcaa agagaattta
     7741 tttagaaaaa gatagaagta taaatagagc tgttcacata aatccaactg aagagaatct
     7801 attgaatata cttaagacaa gtccatatgg aagatgtgtt tacagatgtg ataataatgt
     7861 tgtagacaat atggtaaata tactacagtt tgaaaatgga gtgacggcta cttttaattt
     7921 atgtgcattt actaaagaaa atggaagaac tataaagtta atgtttagcc atggtgaagt
     7981 tggtggggat ttaaataaaa atgagataag aattaaagaa tttggaaaaa acgaagaaat
     8041 agttatgaat ccatcaaatc aacagaatat ggtagaggaa tatgatagaa atcttatagc
     8101 tgaatttatt aaattagttt caaataaaga actagaaaag ggtagagtag cagcaaaaga
     8161 agctatacaa agtcatgtaa tggcatttgc agcagaatat tctagggtca gtgatgaagt
     8221 agtgtatata gaagaatttt ttgatagtgc taagcaaatg actaaggaga tagaagaaac
     8281 tatattttaa ttaataaaaa tttattaaat aaaataaaga tagattaaat aatagaaata
     8341 cgaaaatatg tgttctatta aggaatctat cttttttatt aaggtttttt cttatcccta
     8401 tcaaaaaaat ccatacattc tgataaaaga taagaaagta aagcgaataa gatttctgta
     8461 cttaaaggaa tcgttactga atccataaag gtatcaatta tgttcatagc tagaaaagtt
     8521 agtataaaat caattataaa ttcgcaaagt ttatatattg agtatggtaa tttgtttaca
     8581 tatctgaata tatctaaaat agtagtgcat agaaaatcaa ttggagtggt tatacaaaaa
     8641 tatattaaaa agaaaattaa tacagctcca agagatttat attcaaatcc taagaatgat
     8701 aagaagccaa ttcctataac cgtgaaaata caaaaagtta taccaaaaaa aacagcaaaa
     8761 aataaaaata cagaaataaa ttcgcctaaa ggaatccttc ttttattact tatcttaatc
     8821 aactccttaa tttatgatat gaaatttata taaataataa cattcttaaa aattcataat
     8881 agtcctctgt ttcaaatagt actgtttgag aatctatttt tttcatattt ggataaaaag
     8941 aggccttaaa agctttataa tgttctctaa attttatttc tatcttaaat ttatctggca
     9001 attttattaa gtgcctagat aaatctccag ataaagcttt tttgacacct ttttcaattt
     9061 tttttagtgc aaggtttgga tggattgaaa ttgaaccatt tccaattcct tttgacacag
     9121 gaacagtgac tatatttgga tttagttttt ttgcactctc acaaagcatt tcatctccac
     9181 ttaaaaatgc tacaggaaca ttataatatg cagcaatata agcatttata gtaaattcag
     9241 atgctatttc atcatttatt ttaaaatagt cataatcaat atccatagta tgagaaagtg
     9301 gattaccatt acaagtagct ccagagtgat agccggtgaa tatacatgca tcaaagcttt
     9361 catcaattcc tgccatcata actagtgggt ctttggtcca tcctctaagt attttgacgt
     9421 tttcaggtaa aatatttgga ttaatatttc taccactgtc atgtgcatct ttaacaagta
     9481 tttcatgtac accagattga gtagctccat cacatgctgc tgttatctct ttactcattt
     9541 gcgttctata gtgttgcgaa aattcacatt caagttttgt ttcatcccaa tttacaatac
     9601 cacaagtacc ttctatatca gcacttaaat acaatttcat aatatatacc cccttatgtt
     9661 tattattgat gataataaca gataacagaa aatacataat caataaaggg cataaaaata
     9721 ttatgtctta ctattaacta ttattaaatc tgtaactgaa aaataactaa attggtataa
     9781 aaaaatataa cactatgtgt catttattta tatagttttt tatatttgat gtttatataa
     9841 aattgtaaca tataagtggt tacatttact agtttaacat agttaaaata gttaggtatt
     9901 atttttaagt taaattgatt attataaaat cgcagaataa aagaaaaatt taatttatta
     9961 aaatgcatga aatgtttttt cctcaacata atgctaaatt aaactcaaaa agaaataata
    10021 gaaaaatctt atgtagctta gaaagaatgt gaatgattta agggaaaaat agaaatttat
    10081 tatataatat taggttgtat tatataatac agcctaatat tatatgtata tgtgacataa
    10141 aatcttggta agtgtaaata aaataaatgt ggaaaacaag ttaatgaaat caagaaaaaa
    10201 gtaatttaaa attcaatttc atcttcccaa ttaaattctc ctgatttttc tacactctta
    10261 ggccagtgac tacaccattt aggaacggac ggattttcaa ccctatcaac gcttggagta
    10321 tatggcttta agtcaataac aggactatta tcattagcat caatatatgg tatttttatt
    10381 atgccatttt catggtcgat attgataatt tgtacagcag tcaatgctat tggattgggt
    10441 cttataggtg accttgttgc aaatattcct ataacgtctg gtccactttt ataaggtttt
    10501 ggggtttcta aaatacttct tagttcagga ttatcaaacc catcagccca ccaaaataca
    10561 tttaaatgac tgaaatcgtc gagttcattt aatgcaggta catacttttt gtctaattta
    10621 ataaagacct cttcgccttg aatacatatt ttacctatag gatttattaa tatttctttc
    10681 ataatattac ctccaactat ttaatttatc atttgtaatt ttagggtata acatgacatc
    10741 atgtgagggt caatataaaa taataaataa aaatattaat agttagaatg ataatacatt
    10801 ttttacatgg agcatgacac cagtaataag gcaatcttcg tcaatatcaa aagtagaggt
    10861 atgcaaaggg gaagtaatgt ttttttcacg atttgcacaa ccaaggtggt aaaaagctcc
    10921 ttcacagtgt cttagaaaat acgaaaagtc ttcagcacca agagtgggcg agtctttaag
    10981 gataatattt tcttcaccaa acaattctac agcattttgt ttgacgtaat ctactagatg
    11041 gtttgaattg ataagagctg gataaccttc ctcaatttca acagaaatac ttcctccaaa
    11101 tgttttacaa gtaaaatcgc aaatttctct aattcgtttt tttgaaaact ctctagtttc
    11161 aggagtcaag gttctcaaag taccccttat aaccactttg tcacaaacta tattttcttt
    11221 gattccacct tcaatctttc ctagagaaat aaccacagaa tcagttggat ttgtgtttcg
    11281 actaacgatt gtctgtagag ctgtaataat atgagcagat ataacaatag catcaatacc
    11341 ttgatgtgga taagctccat gacattttga accatgtaca gttaattgaa gtgtattggt
    11401 ggaagcattt agagtgttgt attttaattc aattagattt ttgttgatat tgggatttac
    11461 atggagtcca aatatatatt ttacatttgg tttttcaaga catccatctt ctatcataag
    11521 ttgagcccca ccaatagttt cctcagcagg ttgaaaaaag aattttacat ttacatttaa
    11581 gtaatccttt aatttaaata gtatattaca agtacccagt aaaatagcag tgtgtgcatc
    11641 atgaccacat gcatgcattt tgccaatatt aatagattta taagaataat taagttcttc
    11701 tgttataggt aaggcatcta tatcagctct tatagcaact gtttcaaagt ttggactcac
    11761 gttaatgtat gcagttatcc ctgtatgatt cttatattca atataattta tacctatttc
    11821 atttaagtat ttaataattt ttttcttagt ttgaaattct tctaatccaa gttctggagt
    11881 cttatgtaaa tctcttctta tatttataac ccaatcattt atctcatgac aaagagtttt
    11941 tatattaagc ataaaacaca tcctaactat attaaaaatt tatttttctt cattaattat
    12001 attattttat gtaaatcatt attatgtatc aagtacaaat aaaatatctt ataattatat
    12061 tagagatatt tagtatggag aagaatatat cattttataa gaagaggtgt ttaaatgtta
    12121 ggaataattg cgccatctgg gccattaaga aatacaagtt tggaggaaat aaagtttaat
    12181 ttagaaagtt atggttacga agttaagttt tctgaaagtt gtagtttaaa ttataaaggt
    12241 tatttagctg gtaatgatga tattagagca agggatatag aagatatgtt tttagataaa
    12301 gatgtagata taattatgtg cttaagagga ggttatggaa caacaagaat attggataaa
    12361 ataaattatg atataataaa gcaaaatcca aaaccattta taggtttttc tgatataaca
    12421 ggtttaaatt tagctttcta taaaaattgt ggtcttttac catatcatgg aataatggca
    12481 gcaaatgtag gtaaatgggg taaatttacc tataaatcat tggtaaatgc tttagaattt
    12541 aaagatgaat tatatttaga aaatccaaaa gaagaaaaga tttatactgt atgtgaaggt
    12601 aaagcagagg gaataataat gggaggaaat ttatccttaa taattgccac aatgggaaca
    12661 aaatatgaaa tagatgcaaa agataaaatt ttgtttattg aggaaattgg agaacctcaa
    12721 tataaactgg atagaatgtt aacacaacta tattcttcag gaaaacttga ggaatgtaat
    12781 ggtataattt ttggagattt taaggattgt attgaagaaa atgatttgat ggaattacta
    12841 atagaatttg caaataaggt caataaacct tctatatata atcttcagtc aggacattgt
    12901 atcccaatga taactattcc tttgggcaga atgtgcgaat tagatgctac agaaaaaatc
    12961 gttaaattaa aaaaatagtg tgtatataaa tataatagaa atatggtata atcttataca
    13021 agtaaaaatt tagctaggag gatgaaaaat gtctgatgat agaataatag actttaacga
    13081 actaaagaac aaagttaaag attctgatgt agataaattt gagcaataca tatataactt
    13141 atatttttct gttatggatg gaaagatgtc tatggctgag ttttcaagaa aaatattcga
    13201 ttatatgaga gataacaaca tatctcaaga aaaatttatg aaaatacaaa agcaatttat
    13261 ggagagatat ggtatggaca ctgaagaagt agaaaaacaa cttagaaact ttggaatcga
    13321 cccttctaca gcaggtttta tgagtaataa tacttccagc aaagtatcta cagaagattt
    13381 agagtcattt aagaagagtg caggatttta tgagaaatat ggagaaaaaa tccaaccaaa
    13441 gagttgtata acaacattta taaaaaatga cttaaatgat attaatgtaa taatcgacca
    13501 agaaaagata atgctttgta gtgatagaaa aataaatctt atggattcag aactaaatga
    13561 gtttttatta gaatataaga atatgtttaa taaaaaaata aaggtagtaa tgtgcgaaac
    13621 tacgaataag tatgattatt aaaaaatgaa tttaaatact gaagtagtat aaattaattg
    13681 tactacttaa aaataaaaat cgcaatttat tattccttat aaatttgtat aaggaatatc
    13741 taaactgcga ttttttatat tgtgaagatt agtaataata gatagtgttt taaattgtaa
    13801 tcttctcact aaaactgtgt ttttctatta gaaattttat taaaaataaa tatctgataa
    13861 ttgtattata tgggatgtaa agtattagaa gcttaacgaa tctcttttaa tacattaact
    13921 ccattttgaa tcatactgtt gaaaaatact aagtttaaaa tctcagcagg gtgaacgtta
    13981 ggaatatcat aagtatctac taaattcata ggtacaacta tatttttttc aatattatgt
    14041 tgattaaaat atgattttag agttattgca aattgatata tacatatatc tgtgcaatcg
    14101 ccaactataa ttatattatc tatattatca aaatccaaat tttctaatgc aaaaaatcca
    14161 ttagtagaat ttttaggaag aatttgtagg ttttctatcg acttaagttc atcaaccaat
    14221 tcactttcta catcattttc caaacagtga acaggataac tcaaaagttc tattgattta
    14281 ggagtatgag aatcagtaaa tgctattact ctatttaatt tgtttgatat tttttttgta
    14341 aacatttcaa ttggctttat taaagactct actctaggag agtataatgc accttgtctt
    14401 gcaaagccat tattaacatc aattataaat aaagcagttt tactcaaatc ataattttct
    14461 attttttcta ttggtagatt atctaaatta ctctttaaag cttcaagttc atttaataag
    14521 ttatccatag ttatacctcc aagataaatt taataaaatt gtacatatta attatataaa
    14581 agtcaaggag tacaaactat tgtataatta gctgtattgt tttgagtgta aaagatttga
    14641 agcaatatct ggatagttag taaaaatacc atctacattg agttttagac agtgtagtat
    14701 atcaccctct tcatttacag tatatacatt gacaccaagt agatttttgt gacaaagttc
    14761 aattagagat tcatttacta aaactagagg tggatgaaga taactattac ccagaaattt
    14821 agcaaaattg actacattgt ttataggtaa ataacataat aatcctgttt ttatactagg
    14881 gtctaattta tgaaagtttt ttaaactatt gctgttgaaa ctagatataa gaactctatt
    14941 tttcatatta tactttaaaa taagctctaa aacgtctttt tctatattgg gatagtttat
    15001 tttgtcagtt tttagttcta tatttaaaat aaggtctgta ggtgaaatta gaattaatac
    15061 ttcttctaaa gttggaattt tacattcttt attgctttga tatccttcaa aagatgagtt
    15121 tagagttttt aattttctta aagtaaagtc ttttacaaaa ccatgtccat taaaagttct
    15181 atcaaccttt tcatcatgaa taactacaat ttttccatcc ttagttctgt ggacatcaag
    15241 ttctattcca tatatatcca tatccaaaca ttttttaaaa gctagaatag tattttctgg
    15301 atactttcca ctaaaccccc tatgagcata aatattcatt tatatggttc cctcctataa
    15361 gtataactta tcttataaaa atttaattaa tataatatat catattccaa aaggtattgt
    15421 tatatattag ttaaataact atttgtaatt tatatattat ataaatgtag aaaaataaaa
    15481 tcatatatgt gttataatat attttaaaca ttgtaaatat tacgaattta gtagtcataa
    15541 taagtgtaat tttatgcaag ctcatgtttt tagagcttgc atatgtatta ttaatatatt
    15601 tatatattgt gaaaataaaa ttccaaaaga attttttcta tagacttagt agtaaggggg
    15661 aattttgata tgtatgaagt taatttagaa cgagctatga attattggat ggatttgtta
    15721 gatgattata cgaatatagc aaaaattcca aatgattttt tttataaaga ttgttctgat
    15781 gaagtagtag atgaggtttt taagatgaat attgagaaac atgaaaggtt aattcaatat
    15841 tctaaagtga acaatattag catagactct atcatagaaa ctatatatgg ccttatactt
    15901 caaaagtata tatatgaaga tgatgtagtt tttggtaaaa caatgaatat aattccaata
    15961 agagtaagag ttagacaaag tgaaaaattt atagatgttg taaggaagct aaaaaggcag
    16021 tggagcaggt ctttagagta tggatactat ttgttatcag atatagagaa taaaaatcat
    16081 ctaaatacta agcttataaa cacaatattt atagctaaaa gttttgattt atcatatgat
    16141 tatgacatag aaaaaaaagg atatgattta tctgtaatag tatatactaa gagggcactt
    16201 aaaataaaaa taaagtataa accatctata tataaaagag aaactattag aagaatttta
    16261 aatcaatttg attatataat agagcaaata atagaagata atgatatttt aatagaagat
    16321 ttagaatttg tatgtaagga agaagaaaaa gtattattgg aagactttaa taataatcaa
    16381 tatgaaatac catatgataa aagttatgtt gatttattta gggagcaagt taaggtaaca
    16441 cctagtaata tagctgctag ggatgaaaat agaaagttaa catataaaga attggatgaa
    16501 gtaactgata aacttgcagg ttatttaaat catataggag tggaaagtga agacatagta
    16561 gctgtaatgt taccaagaga tattaacata attattacag caatagggat tatgaaatca
    16621 gggggagcat tttttccaat agacacaagt aatccagaag aaagattgaa ttaccttctt
    16681 gaagatagta atgcaaaagt agtgataact acagatgaac tcaaaagtaa ggttgtaaat
    16741 gagaatacca tagtactcga tataaatgat gaagaaatgt ttaagcttgg atatgaatta
    16801 actgaaaaaa taacatcatc aaattgtgca tatacgatat ctacttcagg gtcaactggt
    16861 aggccaaaga ccatagctat agaacataag agtttagtaa atatgtgtta ttatagcgta
    16921 aaatctataa gcgctacaga aaatgatata tgtggtatat acttaagttt cagttttgat
    16981 gctgtaatga aacaactatt cccttatttg cttgtaggtg catcaataga tattatgcct
    17041 gaagaagcta aatttgatga atatacagta aatgaatact gtgaggaaaa tgacataact
    17101 atactagcat tgccaacagc atttgcaagg ttatttatac aaaattgcaa taataattca
    17161 cttagagttg tacagaccgg aggagaaaga ttaaaaggat atagaaagcg taattatgaa
    17221 ctatataatg agtatggacc aaccgaattt actgttgtat cgacttcttt tcatgtggac
    17281 agagaatatg gaaaaatacc aataggaaaa cctatattta atacttatgc atatgtatta
    17341 gataaaaaga acaaactatg tccaattgga gcaccaggag agctatgtct atcaggcatt
    17401 caaatatcaa gaggatattt aaataaaaaa gggctaacag agcaagtatt tgtagagaat
    17461 ccttacaaaa cttgtgaaca taataagtta atgtatagaa ctggtgattt agtaagatgg
    17521 ttagatgatg gaaatttaga ttatattgga aggatggaca atcaggtaaa aattgatgag
    17581 tttaggatag agctatatga gattgaaaat ataataaata atattacaga aattaaaagt
    17641 gttgtttgta tatcgagaac aaatgatgat ggagatatgt atatatgtgc atattatgta
    17701 attgatgagg aagatagtgg taagataaat gaaagaacta ttagagaata tttaaatgag
    17761 catctacctc catatatgat tccaacaata ataatgagga tagataagat accagttaca
    17821 ccaatcggaa aagtaaataa aagagcatta ccagaataat tttttattat gataggtgtc
    17881 ataaagtgat ttcagacatt tctttatgac acttattttt ataaaagaat caatttgcat
    17941 aaaaacaaga attttctgta tatatttact atggtgaaaa tttatttata agaatgatta
    18001 ttgtattttt tatacttttc cgtgttttaa agcatttttt ttacaaaatt aattttacat
    18061 taaaaaattt ttttatttta tatcttaata gtttttagta gaattgaaaa ataaaaagaa
    18121 aattagcata aaaatatcta aaagtagaaa ttaataatat agggttaaat tttagtagtt
    18181 ttgactcgct atttgtaaaa taataaaaag ttaagtttta tatgtatata tgttataata
    18241 tatacaaatt gaaaaggggt gaaaatttta tgaacaaaaa attacctaag ggtgcttatg
    18301 gtgaggttag tggaaaagat tacgttccat atatcacaga taagtccaga accggtggaa
    18361 atgtagctgt actgattatc ggtattattt tagctgccat ttttgccgca tctacaactt
    18421 actctggaat gaaagccggt cttacagttg ccgcaggtat tccaggagct ataataggtt
    18481 ctgcttttgt tggagcattt gctcgttcaa agggtattct tggtaaaaac ttaatccaag
    18541 gtatgtcaag tggtggagaa tctgttgcaa gtggatttat tttcgtatta ccagcagtta
    18601 tattaattgg aagccaaatt acattctttg aaggcttagc tgttggagtt ggtggagttt
    18661 tatttggtat aggaattgct gctatagttc acaactatct aatagttgaa gaacatggta
    18721 aacttatgta cccagaatca atggctatat ctgaaacact tgttgcttca gaggctggtg
    18781 gagattcaat taagtacatg ggaattggat ttgtaataag tggatttatt actgtattaa
    18841 ctggttcatt cttaaatgta gcaaacaatg taatgagtct tgtaggaagc aaattctaca
    18901 aatggaaatt tgatattgaa gtaaatcctc tacttttagg aattggattt atagtagggc
    18961 ttgaagtttc tttaacaatg tttgcaggaa gtattttatc aaactttggt atagcacctt
    19021 taataggata ctttacagat atggctaaag atggagctat ggtatggaat aatcctgcaa
    19081 tgcctcttaa ccaaatggat gttggagcaa tatctagtag ttatgtaaaa tatataggtg
    19141 ctggtatgat gctttgtgga ggtattattg gtgcaataaa acttatacca actataatcg
    19201 cttctataaa agaaacactt aaagctaaat caagtgctgg agaaggagaa gaaggttcat
    19261 ctatacaaat gatactttta ttaggtggag tagttattgg atttttagca gcattcttaa
    19321 tttctggtaa cattgttatg gcaattattg gagctatcat atctctttta ttatctttat
    19381 tatttgtcat agtagctggt cgtttaacag gaacaatcgg aacatcaaat cttccagttt
    19441 ctggtatgac tatagcttct ctagttattg taacattagt gtttgttata atgggatgga
    19501 ctgatttaga agctaataaa tcattacttt tatttggttc atttatagtt gttgctattg
    19561 ctatagctgg aggttatact caatctcaaa aagtaactta tattattggt ggtagcaaaa
    19621 acgaaatgca acgttacttt acaattgcaa gtatagttgg tgttatagtt gttgtaggag
    19681 taattttatt actttctgac caacttagag caactggtga taatgtacaa tttgcattac
    19741 cacaagcaaa cttaatgtca acattaactt ctggtattat gtcaggtagt ttaccttggg
    19801 ttatgattat tgttggagta tttatggcaa tagttctata tgcattaaat ttaccaataa
    19861 tgactatagc tataggattc tatttaccaa ttgcaacaac ttctataata ttagttggag
    19921 cattaattcg tttatttgtt gaattagtat ctaaaactga aaaagaaaaa gaagttaaag
    19981 tttctaatgg tataagttta tcttctggtc ttgttgctgg tggttctatc attggtttaa
    20041 taggtataat attacaagta actggagttg taactccaaa ggtaccaagt ggatttgctg
    20101 caacaaattc aatggcaatt gctttattag tagttttagt tgtgcttaca gcattaccta
    20161 ttgttttatc taaagtaaaa aataatgagc aagagtaatg atgttttaga tattgtattt
    20221 aaaattactg atggacttga atatgaagta gctgaaaata gagttgttac tatacttgaa
    20281 aaacaggacc ataaaattca aaagtttttt agaaagttaa aagctagaat acctaaatac
    20341 aaaaaaatag aactagatga atattccagt tttgtttttt tacaaattga tggtcaaagg
    20401 actgttagag aaataggcaa gaacctagaa gctaaatatg gagaagaatc tcatccactt
    20461 tatgaaaggt tgttagtatt tttaaatcat attgaagtta attgtcatta tattgaaaga
    20521 ctggatatat agatataata agaattatta tagatatatt agagcatata aattagaagg
    20581 taattatgaa agaggctgtc tcaaaataga gataagcctc ttttgtattg ttgaaatgat
    20641 gaaaatatat ttgatttctc ataaaaaaga gtgtctcata aaactaaaaa gttcattttg
    20701 agacacttcc tttaaaatat ttataaatta cagatttaaa gcaaaactta ttaaacttaa
    20761 gattatttta atattactta ttattagcta tttcatcagc tagattattt aaatattccc
    20821 atctttcata tttgtattca agttcttttt ctagtttaga tttctcatct aaaatttctt
    20881 gaagtttagt aaaatcagtt gaaaattttg cagtactttc atcaagtgtt gcaattttag
    20941 attcgagttt ttctatatca gagtcaatat tttcaaactc cctttgttca ttatatgaga
    21001 acttaagctt tttatcattt ttaggttttt ctttttttag ggtagtagag tcatcttttt
    21061 taactgattc ctttttagat tcttcaaatt caattccttg aatctctcta taaataagat
    21121 aatcactgta attacctgta tagatatgaa tttttccatt accttcatat gcaaatattt
    21181 tattacaaat tctatctaag aaatatctat catgtgatac tgtaactact acacctttaa
    21241 attcgtctag gtattcttct aatattttaa gcgtttcaat atctaaatca tttgtaggtt
    21301 catctaaaag aagcacatta ggagctgtca taaggatttt aagaagatgt agtcttcttc
    21361 tttcaccacc agataattta cctatcaaag tatattgcat agtaccattg aaaaggaatc
    21421 tttcacacat ttgagaagct gtaatcctag taccatctga agtttctata tagtcactag
    21481 cttcttttac atagtctata gccctcatat caatattcat atgagagtcg tcttgagaaa
    21541 aacaacctat tttaaccgtt tctccaattg aaatatatcc actatcaggc tctatttctc
    21601 cattaagtat atttataagg gtagatttac ccataccatt tttgcctatt ataccaattc
    21661 tatctgtacg agttaaagtg tattctaaat tatctataac agtattttct tcaaatgatt
    21721 tagatatatt gtgtatttct attattttat ttccaagtct acttgatgca acagatatat
    21781 caagattttc atcaggttta aaagaatctc tatttataag ttcatcaaat ctttgtaaac
    21841 gagctttttg tttagtgcta cgagcctgag ctcctcgtct tacccacgca agctctgttc
    21901 ttattaaatt ttgtctttta tcttcaatac ttgcttctag cgaaagtctt tccattttct
    21961 tttccaaaaa tattgaataa ttcccatcat aactgaataa tctacctttg tccagttcaa
    22021 taattctatt tgtaacacgg tctaaaaagt atctatcatg agttatcata agcaatgagc
    22081 cttttctgga attaagatat tcctcaagcc aatctatagt atcattgtct agatggtttg
    22141 taggctcatc tagtatcaaa aactcacaag gtgtaataag ggctgatgcc agagagactc
    22201 tctttctttg cccaccagaa agttctgcta ttttttgatt aaagtcattt ataccaagct
    22261 ttgtaagtac tgacttagct tcactttcta aatcccaaag atttaaggca tctatttttt
    22321 cgtgtactga taataatttt ttatttaatt cctctgtaaa gtttgaatta agtttttcta
    22381 ggatttcttg atattcacca agtagcttta attcttcaga agttccatta aatacttgtt
    22441 caagtacagt tgaattttca ttgtaagttg gattttgagg tagatattct atcctaatac
    22501 cattagtttt tgttatatta ccagtctcac tttcttcaac tcctgcaata attttgagta
    22561 aggtagattt accagtacca tttacaccaa taagtcctat tttttcccct tcatttattc
    22621 caagagatat attttctagt aatttttttt cagaatagct tttacttata ttttccaatg
    22681 tcattaaatt catataattc acctttattt ctaatctatt atttttcaaa atgttgataa
    22741 tctgggtttt tccaatagcc accccaactc caacctctgc ttacaaaagc attataacaa
    22801 tcatcacctt tttttatcat tccaaatttt gtgctagacc tatcagcata aactgtactt
    22861 actttaggtg taacatcatt tccagaaact tgaggattct gtaatgggtt tatatctata
    22921 gcacgtcctt taccatgatt tgaaactaca tttgtaccag ctatagttct ataacaaaat
    22981 gatgaggtat tattatcaga catagatttt tcatctacag catcatagtc atctattaac
    23041 ttaatttttt caattggata ttttttttcg tataattcct taaaaatatc cactacttct
    23101 ggagctagtt cactgtttac tatcatttct ccttgatgag ttttttcatc aaatccataa
    23161 tatgtaagtt ttaaataaga tagactatca aagcttatag gttcatcagt aggcatagat
    23221 ttaccaatca ttttattttt tatattatct ggtattgaag aatatgaaaa agtaggcttg
    23281 atattattat cttcctgctt tttggtagag ctttgattat ttttagaatc atctgttgta
    23341 ttatttttat tttgcatagt ttcttgactc tttatattac cttttttgtt gggattagag
    23401 aacagtatct catatataga taataaagca agaaataata cagttattac aatcgttaat
    23461 tttaatttat taatttttct tcgttttgac tttttactca tattatcccc cagtattaga
    23521 ttcatataaa ctatatatat tatacctcat aaaaataaac taggctaaca atatttagtt
    23581 aacctagaac atttcattta tagtttctcc aattattttt attccaattt caatgtcttc
    23641 aaaagacaac ctagaaaatc cgagtcttaa agtatcaaaa ccagagttat ctgtaaaaaa
    23701 taaatctcca ggcataaata taacattttt ttcataacat ttttctaata aaactctagt
    23761 atctatattt tttagtttta taaatatatg caaaccacca tcacccaaga tatattctgt
    23821 ttttatatat ttttttatac acttatatgc aaagttaaat ttgtccccat agaatttacg
    23881 tattttttta atgtattttt caaaacctcc attacttaaa taatcaaata aaattccttg
    23941 gtccaaaaag gatacatgta tgtttctgca cctttttaca ctttctagct tattgattac
    24001 ttttttatct gcaaatatcc atccaattct cattccagga aataaaattt ttgaaaaact
    24061 accaatatat acgaccccat tattcatatt atctagggaa cagataggaa atatatgaga
    24121 actattgtag agtaattctt cattaaatcc atcttctata attgctatat tgtatttttt
    24181 cataagatta tagaatttgt acctattttc aggagtcatt acaattcctg taggattgtg
    24241 ataagagggt gtaatgtatg caaactttat tttattttta tacttaacta aattgtcttc
    24301 tagcatattg aagtccaaac catcttcatt tatatctaca cctaagatat tgaggttatg
    24361 agatttcata atttttatag cagtattatg agtaggattt tcacatatta tgtagtcttt
    24421 ttcttgggta aaagatgaca taataatatc aaagccttct gtgaatccat ttgttattag
    24481 tatatcttta ttacttatat cagcaccctt atttgtcata tattctagta aatagtcaat
    24541 aaggggctta taaccttgtg catatccata gttgagtaat ttatgtcctt ctagtgaaat
    24601 tctatttaaa aaggattttt ttaattcttc tatgtcgaat aaatctccat ctggagaaat
    24661 acttttaaag gaaatcaggt cagagctcca aggaatttca ctttttataa tgtccaattc
    24721 attggctttt ttagagtatg tattctctaa acaatcccag tttaatgacc atgtagtatt
    24781 tgaagactta ttctttgatt taacaaatgt accttttcct gaaatagagt agattaatcc
    24841 ttctgatttt aattcttcat aagttaaaac tacagaattt cggctaactt gtaaaagctg
    24901 actaagctcc cttgtagaag ggagcttact attgtctgga attagtcctt ttgatatcat
    24961 atcacttata taatttttaa gttgtatata aattggttca ttatcattta gttttagatt
    25021 tgaaaatatc aaattaccac ctcaaattat ttcatctaat ttaaagagta ttctataagt
    25081 ttatctaata gttcactgta cttaatacct ctagcagcag cacttctagg aattaaacta
    25141 gtttgagtca ttccaggaag agtatttagt tcaagaacat atggaatacc ttcacttata
    25201 atcatatcaa ctcttacata tgctttgcaa ttaaaaattt tccaacaagt ctcagaaatt
    25261 tcgtttactc ttttttgaag ttcttcatct aagtaaacaa cttcttcctt tgcacctttt
    25321 tcaactgagt acttagcttc ataatcaaag aatcctgaat cagattttat agatattgta
    25381 gggaacactt ctccatttaa tatgaatgaa gtatattctc cacctggtat atatttttca
    25441 atcattacaa attcatcaac ttccagacct tttctaactg cttcttcaac ttcatcctta
    25501 gaatgaataa agaatgtggc tacacttgaa cctcctgagt ttggttttat aaatactgga
    25561 taacctatat tatctatttc atcatagtct atttcatcaa ctgattttac taaaacccat
    25621 ggagcagtag gtaggtttga atctctaagc atttttttag ttatattttt atccatacac
    25681 atcccactgc aaagaggtcc acatccagag tatggtatat ccatagtctc aagtattgat
    25741 tgtatacatc catcttcacc aaattttcca tgtaaagcaa gtattgcaaa atctatatct
    25801 tctggtatct ttgtaaatat atctttttta tcatctatta ttacttttac aacttcatat
    25861 ttatttttat caaggttatt atatatctct tttcctgaat ttaaagaaac ttctctctct
    25921 gatgatattc cacccattat aactgctatt ttcatattat acactcctat tttaattttt
    25981 attattttaa agtaaacttt ttatttacat acttaattat atgaattaac agttgaggat
    26041 gaaagtacca ctatatacga agtttatatt atgtgtggtt ttagaataat aatctagttt
    26101 aaagatatgt ttaaatgatt ttttaacttt atttatgtta ttatttttgc taaaattatt
    26161 gttatgaact taagactagt cttaatggct ataaatcaag gagtgataaa ttttgaaagc
    26221 tgaaataata agtgtaggaa cagaaatatt attgggagat atagtaaata caaattctca
    26281 atttttagct aaagaacttg catcattggg aatagaagta taccatcaga gtactgttgg
    26341 agataacaaa caaagacttt tagaatgttt tgatgaaagc ttaaagagaa gtgattttgt
    26401 aattactaca ggtggtcttg ggccaactgg tgatgatatg acaaaagaaa ctgctgcaga
    26461 atactttggt cagaaattag aactacataa accttcacta gaggttttgg aatctttctt
    26521 tgttaaaaca gggaaaaaaa tggccgaaaa taatatgaaa caagtgtact ttccaaaaga
    26581 tgctatagta ctaaaaaata ataatggtac agctccaggg gcaattttaa aaaaagatgg
    26641 taaatttata atagtattgc ctggacctcc aagagaaatg aaagctatgt ttaatgagag
    26701 tgtcaaacct tacttacaac aattcacaaa tgaaatgcta gtatctaaga ctttaagatt
    26761 atatggaata ggtgagtcaa atctagaatt agaaattctc gatataatta atgagcagac
    26821 taatccaaca gttgctttat atgcaaaaga attagaagtt acaataagaa taactgcaaa
    26881 ggctgaaaat gaaagagaag cttttaaatt aataaaacca gtagaagaaa aaataaaaag
    26941 tagagttggt aaatatgtat atactgaagg agatatttcc atatctgaag gggagactgc
    27001 tttagaagat gctgtttcta agctacttgt agaaaaaaat ctaacaatag cagtggctga
    27061 atcttgtact ggaggtttgg tttcttcatc tcttataaac tatccaggta tatcctctgt
    27121 atttcttgaa ggttgtgtaa catattctaa tgattctaaa atgaaaagat taggagtaaa
    27181 aagagaaact ttggaagagt ttggagcagt aagtgagcaa acagctatag aaatggctga
    27241 gggcgttgct aaaggactta aagctaatat aggtatatct acaactggag tagctggacc
    27301 tggtggagga accaaagaga agcctgtggg actggtttat actgcaatat atataaatgg
    27361 aaaaacaata gtaaagaaaa atatatttaa tggggataga agaaagataa gattaagagc
    27421 tactagagat ttgcttaatg agttgagaat acaattagaa aagctttaag ttattttgat
    27481 taaagtatta gtaaaatata aaattgtttt tggaggcttt taatttatga taaaacatat
    27541 attttgtgat ttagatggaa ctctatatga aaatggaacc ataacaaaag aagatatagt
    27601 agcaattgaa gaaatagaaa aaaagggagt acagtttaat gttgctacag gtagaatttt
    27661 taaacaagca cataatatta tcaaagatag tttagatatg aatggatact atgtatgtga
    27721 aaatggttca tttatatatg ataaagatta taatgtaatt tttaaaagaa cgatagatga
    27781 taatttagta aaaaaagtca ttgatagatt tgagtcaagt gatgcacaac tttattttaa
    27841 atataagggt gatgtaattg tgggtagtga taccactgct tttagacatt attctagtga
    27901 ctttatagtt gacccagact ttgaaaaaag aagtagtttt gataatctta taggaaatat
    27961 aggcgtatgt tctgaaaatt tggaagagtt atccagaata gaactttatc taaaaagtga
    28021 gtttagtgaa gtcttagaaa tatatttttc tggaacatat actttaaata tagttcctaa
    28081 aagtgtgtca aaaagaggaa gtatagagca tgtaataaaa acgttaaatg taagtccaga
    28141 tgaagttgct actattgggg attctccaaa tgatatttgc atgttagaag gatttaaata
    28201 tagttttgca atgtctaagg caagggaaga tgtaaagcaa agtgcaaatt atgtagtaga
    28261 tagtgtaaaa agtgccatag atgttataat ggagataaat agttagtata aaaaatgact
    28321 gtcctagaga agtataaaat tatattctat agagcagtca ttttaattat attcaattat
    28381 aagtttatat aagtttaaaa attcttaagt taaccgcaat ttgctatatg atatgatttt
    28441 attgtattag ataaaataga gtcaagtata taatttatga cactattaca agtataagct
    28501 gaaaatttta aatcattcat ataatcagtt ttctttttgt aatcgctata aagtttagta
    28561 aaaaacttct caaaactact atttatagta ccacatttaa ttttagataa atcaacatct
    28621 tttgcaaatg ctccaagttc tctttcataa gtaacatgtt tatttaagct atgcttaaac
    28681 tcccaacgtt cactgtgagc tacacagaaa aaatcacata aaaaatgaca tatgactcct
    28741 agttcctgac taagtctact tactgaaaag tatttagaaa gactatctat attaagactg
    28801 catagatagt ttattttaga aacaatcata ttaaatgact catctaaata atgttttttt
    28861 aatttatatt tagaaaaagc atcaggcttt atattgccat atataaaatt tttttcgctt
    28921 ataaagaatg ttttattttc atctatatta tcaagtattg attttgccat aataaaatgg
    28981 gtattcatta acatatttac acctcgt
//
LOCUS       DAJMZY010000043        28807 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.043, whole genome shotgun sequence.
ACCESSION   DAJMZY010000043 DAJMZY010000000
VERSION     DAJMZY010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 28807)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28807)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28807
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.043"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            <1..868
                     /locus_tag="OE968_001862"
     CDS             <1..868
                     /locus_tag="OE968_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="M56 family metallopeptidase"
                     /protein_id="HCP7219143.1"
                     /translation="IILYTWIITVVVYLIYTIFKYIKLKNLINDLSYDVDDREIVNLY
                     KNILEEFNITKDIKLKYSYEVETPAFFNSCVLLPPHEYKLKELDWIFRHELMHFKSRD
                     LYLKYVILFLKTVYWFNPFIYIMDKHIDLDCELYCDERVLKNRNSEEKKDYALTILNA
                     MRKGSNTSNKFIAGLHKQSDIKKRVMNMFNEKYKNGILMALTLCLLSSITFLKVNSTS
                     IVNLNVLPKGFEDLRTVSSIRFSVIGFTYADAPKNMREEYKINCESLGLIPKDSDKIE
                     VGIEYYDSLLND"
     gene            1784..2806
                     /locus_tag="OE968_001863"
     CDS             1784..2806
                     /locus_tag="OE968_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HCP7219144.1"
                     /translation="MKKKILIPVFASVMALSVSSIVNADEVNDSSQNKDDKTNTELNL
                     GEYKEVKYKVAKIKDGVAIKIREEGQVQNIAYSGDEFTVLGTQGEWVKVKVEDGEGWL
                     ATRYVDISEGVGYTNADKVNLRKDKSESSEVIEELEKGSSLLVLEDNGDWLKVKDGET
                     EGYVKSSYISDKAPVIEEPQVNPSIDQNVDSTNNNQQNNANTNQQNNNSNVPTANSNA
                     VQAVLNLAYSKQGCPYVWGAEGPNTFDCSGFTQYVYRNAVGKNIPRTSKAQSKYGQTV
                     SKANLQPGDLVFFTTNGSGSVSHVGIYVGGGNMIHSPSTGKTVSVTSINSSYYTARFV
                     TAKRIL"
     gene            3103..4023
                     /gene="pyrB"
                     /locus_tag="OE968_001864"
     CDS             3103..4023
                     /gene="pyrB"
                     /locus_tag="OE968_001864"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase"
                     /protein_id="HCP7219145.1"
                     /translation="MLKSRNLIQPEDFSIEEIDEILELAQKIIDNPSKYSRICEGKLL
                     ATLFYEPSTRTRLSFESAMNRLGGRVVGFSEPNSSSASKGETLGDTMRIVSGYVDIIA
                     MRHPQSGAASEAARYTEVPFINAGDGKNQHPTQTLTDLLTIKSLKGTLESHTIGLCGD
                     LKYGRTVHSLVKAMARYKNTKFVFIAPEELKMPDYIKEAIKGHAYYETNNLDDVIGSL
                     DVLYMTRVQQERFEDKSEYERLKNYYILNKAKLEKASKDMLVMHPLPRVNEIDIDVDS
                     DDRAVYFKQAKYGMYVRMALIIKLLGINED"
     gene            4062..4754
                     /locus_tag="OE968_001865"
     CDS             4062..4754
                     /locus_tag="OE968_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HCP7219146.1"
                     /translation="MYKILENIYIGEDMYRMKVKGNFEGKMGQFYMLRAWDTYPVLSR
                     PISIHDIDEEGITFLYKVVGEGTQILSNLKVNDTIKLEGPYGNGYAKVDGKVALVGGG
                     IGVAPLYLVAKNIKNCDAYLGFREDVILEDEYKQVCNKVYTTVGNTFVTDIIDVEKYD
                     YILTCGPTPMMEKLVKMVEGTKTRIMVSLENHMACGVGACLVCTCKTNGGNKKTCKDG
                     PVFWGEDVIFNG"
     gene            4747..5649
                     /locus_tag="OE968_001866"
     CDS             4747..5649
                     /locus_tag="OE968_001866"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HCP7219147.1"
                     /translation="MGNLSVKFGSVEFKNPVIMASGTFGFGKEYNEIYDIQKLGGISS
                     KGLTLNKKPGNNGMRVHETPSGMMNSVGLENPGVQGFIDYELPFFSKLDLVRIANVGG
                     GTLEDYLLGVQMLNDKPIDIIELNISCPNVKAGGMAFGIKNEVAREVVREVRNITKLP
                     LVIKLSPNAEDIVGMAKVCEEEGADGVSLVNTFKAMAIDIKNRRPVFENVYAGLSGPA
                     IKPIALRMVHEVCKNVNIPVMGMGGITKATDAIEFIMAGATCIQVGTANFMNPRIGIE
                     IIDGINEFMDREGIKSLDEIRGII"
     gene            5734..6318
                     /locus_tag="OE968_001867"
     CDS             5734..6318
                     /locus_tag="OE968_001867"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HCP7219148.1"
                     /translation="MSKVDVVDILKKSDALLEGHFLLSSGKHSNRYVQCAKVLRFPEY
                     AAEVLSTVVEQIKDLDIDLVVGPAMGGVIVSYELGRQLGKEAVFTERKDNTMELRRGF
                     EVKKGAKIIIAEDVVTTGKSTMETKRVLEALGGEVVGVACIADRTNHDIGMPIYSAIK
                     LDIQVYESDECPLCKEGKLPVVKPGSREFKELGM"
     gene            6533..7459
                     /locus_tag="OE968_001868"
     CDS             6533..7459
                     /locus_tag="OE968_001868"
                     /EC_number="1.1.1.169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HCP7219149.1"
                     /translation="MKNQLNENHKKVVFFGVGAVGATFAEQFFNSKYDFKILCDNERK
                     KRYLEEGFIINGKRYDFDYVTKDEYKQEADFIIIGLKYNNLKENIKELDGLVGKNTVI
                     MSLLNGVDSEEIIGERFGIEKMVYSYVTNIDAKKINNNIIHTTNGIIVFGNKDNSEDR
                     KTNIITEVFDDVNIEYTLSKDIQRDMWWKYMVNIGVNQTSAILGAPYGVFQSSEHLRE
                     LAKSAMREVVAIAQAKDISLTEDDVEHSLHRILEHSKEGRTSMLQDVEAHRLTEVDMF
                     SKNICKLGKKYNIPTPINQTFFYMIKVIESRF"
     gene            complement(7511..8401)
                     /locus_tag="OE968_001869"
     CDS             complement(7511..8401)
                     /locus_tag="OE968_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCP7219150.1"
                     /translation="MFEELKTFVAVVEYKNFTKAGEYLNLSQPSVSKHIKNLENYFKV
                     VLINRSIKQKTIFITESGQILYKRAKEILNLLNITYHDVSQVSDAITGHLKIGASLTI
                     GEYILPNFLALFSKKYPDIDVEVFIKNTSIVSSHVKDYILDIGLIEGTCSSPSFIQEY
                     FFEDKMVLALPYKSHLLKDFSFDKLQNQKWIVREDGSGTRDYLDMFLSVKEIIPKSMM
                     VFGSNYAVKESVRNNLGITIVSNLVTSLPVLNNELSVIELGSSYNRHFSYIFPKDITL
                     SKAATIFIEELKIFSNLNSI"
     gene            8589..9620
                     /locus_tag="OE968_001870"
     CDS             8589..9620
                     /locus_tag="OE968_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HCP7219151.1"
                     /translation="MLKKKSSLTLKTIREILPGLFVSVLVGYISIFISILIPKVGAAS
                     ISIFLGMFVGNLFLNQKVFQKGYKFSETDLLSYSIVLLGATLSVSTLIDLKVSGILFI
                     ILQMTITIIAALYIGKKLGFEENFRFLMASGNAVCGSSAIGATVPVVNATDKEKGIAV
                     TIVNVTGIFLMFLLPIISQFLYSHELVKTSAMIGGTLQSIGQVVASGAIVGENVKDLA
                     TIFKIVRVIFLVVVVLVFGHMKNQSNREILEEEKDEIKKKKVTIPWYVIGFFITCALF
                     SMNIIPQEVSVLCKEISNKLEIIALAAIGLKVNVKDLVKQGKEVSLYGLFVGIVQVVS
                     AVVLIKIFI"
     gene            9914..10789
                     /locus_tag="OE968_001871"
     CDS             9914..10789
                     /locus_tag="OE968_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA glycosylase"
                     /protein_id="HCP7219152.1"
                     /translation="MNVYEKGNGVILEGVTDFDPVHIFECGQCFRWHKQEDGSYTGVA
                     KGRILNVKKENDKIYLNNTNLKEFNSIWYNYFDLGTDYTEIKNKLKNMDEYLNKATEF
                     GWGIRILRQDGWEMLISFIISSNNRIPMIQRAIENLSRKFGKYIGEYEGNEYYAFPTP
                     EELNKASQEEIRACQTGFRDKYIKSTTQAVIENNDEVSEYTNLSTEDCRKELLKFNGV
                     GPKVCDCIALFGMQKYDSFPVDVWVKRVMQEFYIDEDMSLPKMRTYGIDKFKEMSGFA
                     QQYLFYYARELGIGK"
     gene            10807..12297
                     /gene="cls"
                     /locus_tag="OE968_001872"
     CDS             10807..12297
                     /gene="cls"
                     /locus_tag="OE968_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HCP7219153.1"
                     /translation="MGVIGTIFLFYLIISYLAGAIISVIILLENRDPAKTMSWLLMFI
                     IFPGVGLMIYAISGRNIRKRKLFKTQKLANNIKEKKLFDTLEKITEIVELEKESIKQN
                     KLLRDEEDGSYRKRVINMLLKTGMFPFTKNNKVDVFVDGNEKFKRLIEDIREAKDHIH
                     LEYFIIKDSEIGRVLKEELIKKAKEGIKIRILYDDVGCWRFWFNRKFFREMREVGIEI
                     AAFLPTKFPIIGGKLNYRNHRKIVVIDGIIGYTGGINIGDEYLGKNDKFGYWRDTHIR
                     IKGISVYMLQMTFLIDWYYTTKEVLVTKNYFPSVGNVGESMIQVVASGPDSDWEDIHY
                     AYFSAICQARKNVYIETPYFIPDESLLKAIKSAALSGVDVRIIFPKIADHKIVNIASY
                     SYFEEILRAGGKVYLYNKGFIHSKVVIIDDKIASAGTANMDLRSFMLNFEVNAFIYDE
                     EVIRVMTDDFFEDLSHCEELNLEVFKNRNIIQKIKESVARLFSPIL"
     gene            12490..12774
                     /locus_tag="OE968_001873"
     CDS             12490..12774
                     /locus_tag="OE968_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012062101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HCP7219154.1"
                     /translation="MKIRPLADRVVIKKVEAEEKTASGIVLPGAAKEQPQIAEVVEVG
                     PGGIVEGKEIKMELTVGDKVIFQKYSGTEVKIEGQEYTILRQSDVLAVIE"
     gene            12807..14435
                     /gene="groL"
                     /locus_tag="OE968_001874"
     CDS             12807..14435
                     /gene="groL"
                     /locus_tag="OE968_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729227.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HCP7219155.1"
                     /translation="MAKEIKFSEETRRALEAGVNKLADTVKVTLGPKGRNVILDKKFG
                     SPLITNDGVTIAKEIELEDRFENMGAQLVKEVATKTNDVAGDGTTTATVLAQAIIREG
                     LKNVTAGANPILLRKGIQKAVTVAVEELKNQSRIVETQEAISQVASISAGDEEVGKLI
                     AEAMEIVGKDGVITVEESQTMNTELDAVEGMQFDRGFVSAYMVTDVDKMEAVLNDPYI
                     LITDKKISNIQELLPVLEQIVQQGKKLLIIAEDVEGEALSTLVVNKLRGTFDVVAVKA
                     PGFGDRRKEMLQDIAILTGAQVISEELGYDLKEADLSMLGRASSVKVTKESTTIVDGS
                     GDKKAIEDRVTQIKHQVEQTTSDFDREKLMERLAKLAGGVAVVKVGAATEVELKERKL
                     RIEDALNATRAAVEEGIVAGGGTAFVSVIPAIGTLIESLEGEVKLGAQIVKKALEEPL
                     RQIAINAGLEGAVIVQNVVNSEAETGFDALNEKYVNMIEAGIVDPTKVSRSALQNAAS
                     IASTFLTTEAAVADLPEKEDVGMPGMGGGMPGMM"
     gene            14697..15437
                     /gene="larB"
                     /locus_tag="OE968_001875"
     CDS             14697..15437
                     /gene="larB"
                     /locus_tag="OE968_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel pincer cofactor biosynthesis protein
                     LarB"
                     /protein_id="HCP7219156.1"
                     /translation="MDLRKLLEEVKNENIDIDFALEKLKDLPYEDLGYANIDHHRELR
                     NGYPEVIYCEGKSDEHILGIIDKMNQKSSNILGTRCRKETFLKIKEIYNHAEYEEASK
                     ILKIQNHDIENIGKGKIVIATGGTSDIPVADEAYHTAKFLGNDVDRIYDVGVAGIHRL
                     LNKRHKIDSARVIVAVAGMEGALASVIGGLVDVPVIAVPTSVGYGANFGGLAALLAML
                     NSCASGISVVNIDNGFGAGYLASMINKL"
     gene            15521..16255
                     /gene="larC"
                     /locus_tag="OE968_001876"
     CDS             15521..16255
                     /gene="larC"
                     /locus_tag="OE968_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel pincer cofactor biosynthesis protein
                     LarC"
                     /protein_id="HCP7219157.1"
                     /translation="MSEKILYFDIISGISGDMTLASLLNLGVPKEIFLEEIHKLRMSD
                     EFNINISSKTENGIVGTKVEVITKEKHTHRNLVDIFEVIDKSTLNENVKSKAKKIFMV
                     IGEAEAKVHGTTIDKIHFHEVGAIDSIVDIVGASILVDLLCVDKVCASTVSVGSGFVK
                     CEHGIIPIPAPATIEILKGVPIKLNNVNGECTTPTGAAIIKVLCDEFVDELEFSPKQI
                     GYGIGHKKFEVPNILRTVLGEKKKKN"
     gene            16285..16704
                     /locus_tag="OE968_001877"
     CDS             16285..16704
                     /locus_tag="OE968_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF111 family protein"
                     /protein_id="HCP7219158.1"
                     /translation="MSSEIYSYLYEKILDEKALDIYTESIYMKKNRPATKVSILCNES
                     DLEKFIKILLLETSTFGVRYNAYNREILERKFVKLDTKYGVVTVKLGYYKGKLVKATP
                     EYNECKTIAKNEDIPIKKVFADINFRIKEEFSENLLT"
     regulatory      16764..16865
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            17086..18621
                     /gene="guaA"
                     /locus_tag="OE968_001878"
     CDS             17086..18621
                     /gene="guaA"
                     /locus_tag="OE968_001878"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HCP7219159.1"
                     /translation="MKHELVLVIDFGGQYNQLIARRVRENNVYCEILPCTASIERIKE
                     KNPKGIIFTGGPNSAYLEDSPTISKEIFELGVPILGICYGIQIMSHVLGGVVRKGNKQ
                     EKEYGKTAITYGKSSLFEGITTNSVWMSHTDLIEKVPEGFTIVANTNDCPVAAMENVE
                     RNLYGVQFHPEVEHCLEGDKILTNFLYNICKVKGDWTTDSFIEDKIKELKEKIGDKKA
                     LCALSGGVDSSVAAVLIHKAIGDNLTCIFVDHGLLRKNEGNDVERIFREKFDINLIRV
                     NAEDRFLSKLKGVSEPEAKRKIIGEEFIRVFEEESNKLGKMDFLVQGTIYPDVIESGH
                     GNAATIKSHHNVGGIPEDVDFQEIVEPLRELFKDEVRKIGLELGIEEGLIFRHPFPGP
                     GLGIRVIGDVTKEKCDILREADAVYMDELRKAGLYREIWQAFATLPDVKTVGVMGDER
                     TYAYLVGLRAVTSSDGMTSDWYKMPYDVLERISNRIINEVDGVNRVVYDITSKPPGTI
                     EWE"
     gene            complement(18698..19744)
                     /locus_tag="OE968_001879"
     CDS             complement(18698..19744)
                     /locus_tag="OE968_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003460085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HCP7219160.1"
                     /translation="MPAYKDEQRKSWYASFYFTDFDGDRKKKIKRGFKTKKEALEFER
                     EFLNKSKMSTDMSFESLIEEYMHDMSSRLKLSTLETKKYLINFRILPFFKSLKINEIT
                     ATHIRRWQNELLKSDYSQTYIKTINNQLVAVLNYAVKYYNLPSNPAHLAGSIGKKNAD
                     EMNFWTLEEFKKFIEFEKKSEPRLAFEILFWTGLRLGELLALTPKDIFENKISVEKSY
                     IRLNGEDIVSSPKTPKSKRVVPIPHFLYNNIKDYLSKLYDLKDNERIFKFAKSYLSKE
                     LDRCCKLSNVKRIRVHDLRHSHASLLVNMDVNILTIAERLGHEKVETTWNTYSHLYPN
                     KQLEVAQKLDNLNI"
     gene            complement(19821..20036)
                     /locus_tag="OE968_001880"
     CDS             complement(19821..20036)
                     /locus_tag="OE968_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCP7219161.1"
                     /translation="MLKKLRKKKRMTQLELAEKMRRNRSYISKLENQEYKDIGISTIL
                     DLSIALEEDFLELCKYYKLQEIKRRGK"
     gene            complement(20470..20871)
                     /locus_tag="OE968_001881"
     CDS             complement(20470..20871)
                     /locus_tag="OE968_001881"
                     /inference="COORDINATES: protein motif:HMM:NF013540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCP7219162.1"
                     /translation="MQTLAEIIKEYRSEHNLSLREFSNLCGVSHTYIDKIEKNRDPRN
                     GKAVEPTLDMLEKMSFGLNLTLKELLTKLGKIQPNTQQDDELLKKVNSKEDNEVNELI
                     NRLASLDSDDKNAIKKMIDNAYYKAVNTKKE"
     gene            21036..21248
                     /locus_tag="OE968_001882"
     CDS             21036..21248
                     /locus_tag="OE968_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019161272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCP7219163.1"
                     /translation="MKNNLQYIRKESRISQKKFADKIGISRPYLSRIENGKVNPSLEI
                     AHKISLETGKTINEIFFDFTVNHSKL"
     gene            21488..21625
                     /locus_tag="OE968_001883"
     CDS             21488..21625
                     /locus_tag="OE968_001883"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219164.1"
                     /translation="MQREQTTLRIPEDLHKALIDLSSDIGMPITSIIIIACWLYISKI
                     N"
     gene            complement(21611..21922)
                     /locus_tag="OE968_001884"
     CDS             complement(21611..21922)
                     /locus_tag="OE968_001884"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219165.1"
                     /translation="MTTITVRIYTPLNENLEKISYQTGILKSSLILYAINDIIRNSKV
                     NELQSISYKSDDTVRSTLRIPGVLKELLEKTAKENNLSINSLINNVVHSFCISDWLIY
                     L"
     gene            22043..22213
                     /locus_tag="OE968_001885"
     CDS             22043..22213
                     /locus_tag="OE968_001885"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219166.1"
                     /translation="MEKVRMTVRLVPKLNQYVQNIAKECGKSKNSIIVDACWEFIEKI
                     KKENKFNVESEE"
     gene            22216..22854
                     /locus_tag="OE968_001886"
     CDS             22216..22854
                     /locus_tag="OE968_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219167.1"
                     /translation="MNNLQIFEKLEFGQIRMAEIDNKPYFVGKDVAKSLGYKNTNDAI
                     LRHCKGVVKHEGFKINGIKIALITEGDVYRLIVGSNLPNAEKFESWVFDEVLPSIRET
                     GQYQAQQHVITELTGTIGDLKGTIKEYKKLCKITCSKKQQYSKYIKNRLDIDKANKEY
                     NQVKARLFLILGVEKWEDIDFDTSNNLIQIIDDCIRVIKSERPYKQLSYFEN"
     gene            22913..23083
                     /locus_tag="OE968_001887"
     CDS             22913..23083
                     /locus_tag="OE968_001887"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219168.1"
                     /translation="MKNNISDSRVKYFCKCPYCGFDNEVEVKKGLKPKICCICTKEVE
                     YEKLEQQSTPAK"
     gene            complement(23086..23319)
                     /locus_tag="OE968_001888"
     CDS             complement(23086..23319)
                     /locus_tag="OE968_001888"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219169.1"
                     /translation="MNIGKITKIEATCFDCGTKVTITESKFREVCDNGLPCPMCKEHI
                     SNSNFIAEQALQYNHAVNKLEKELDSCKNIHIY"
     gene            23388..23585
                     /locus_tag="OE968_001889"
     CDS             23388..23585
                     /locus_tag="OE968_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCP7219170.1"
                     /translation="MAINDNINKILRDRNLKAWKLAKEIGVDSGNLYAILRGENKNPT
                     IDTLIKLADYLDVTLDELVGR"
     gene            23624..23833
                     /locus_tag="OE968_001890"
     CDS             23624..23833
                     /locus_tag="OE968_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219171.1"
                     /translation="MAKAVAKEQLFYRAKDIAKILDVCEATAYKIIGELNKELEKEGF
                     KTFSGRVSVAYFKERYCYKPRKGVI"
     gene            23991..24203
                     /locus_tag="OE968_001891"
     CDS             23991..24203
                     /locus_tag="OE968_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219172.1"
                     /translation="MVFNLEKFKVGNAIRISCERFGFEIDCIVVVATEKELNLAYFDE
                     GRGCMEYQALITEDIQDGDYEIKILS"
     gene            24302..24544
                     /locus_tag="OE968_001892"
     CDS             24302..24544
                     /locus_tag="OE968_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219173.1"
                     /translation="MEAARLIAMGQIKQAEKEISKLQGTKNNSSLMWWEAVKFASQNI
                     LQGLEHDIELEASTDFREFMITQEELERDRPIDVQI"
     gene            24628..25137
                     /locus_tag="OE968_001893"
     CDS             24628..25137
                     /locus_tag="OE968_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siphovirus Gp157 family protein"
                     /protein_id="HCP7219174.1"
                     /translation="MSTLYELTTDLLEIEEGLTETTGNEAEKLEEIKEIIKQEIQNKN
                     TRIVSVILNIDSDINSIDSEIKRLQELKRVKKNTLDRLKSNIKDCMELLGTKKVETVL
                     GNISIRKSAGSLVIEDEEKIPAIYKTVEQVVKVDKNTIKDFIKKGHEVEGCRIEYGTT
                     LTIPKAKKE"
     gene            25147..25761
                     /locus_tag="OE968_001894"
     CDS             25147..25761
                     /locus_tag="OE968_001894"
                     /inference="COORDINATES: protein motif:HMM:NF016302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ERF family protein"
                     /protein_id="HCP7219175.1"
                     /translation="MEINNIYIKLMDVRVKFSKLNLKKSGENKFANFKYFELADFLPQ
                     ATGLLEEAKLCPIVTFTNEYATLTLINGENPSEQIVFTSPMRDLQLKGSNELQALGGI
                     ETYQTRYLYIQLLNITENDSFDAVSGKEESKSNSNNNVKQSNRILTDKQLTRLYAIAN
                     SVGVNKALLKEQVFKQLGKDIKDLNKSEYDAVCAAYEKQAFKGA"
     gene            26538..26636
                     /locus_tag="OE968_001895"
                     /pseudo
     CDS             26538..26636
                     /locus_tag="OE968_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420554.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
     gene            26706..26957
                     /locus_tag="OE968_001896"
     CDS             26706..26957
                     /locus_tag="OE968_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219176.1"
                     /translation="MIIIRSQDRLDLMRVNRVEIGFNQVYAILENDIRKIGEYESIER
                     AMQVLNDIQKFIENGVRTDYIDSCRVRHNQEKVFEMPFE"
     gene            26975..27331
                     /locus_tag="OE968_001897"
     CDS             26975..27331
                     /locus_tag="OE968_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219177.1"
                     /translation="MAKVWVDAGTFLERTKDIEDMFEFNLRKVRDRNKKINVIDLRVN
                     NEGQGRKGKKVECFNIVTGETKVFNTAVEASKYVYFTDVYIAHLARTGKVSKNGWKAR
                     YIQEVTDGIGKCGTSN"
     gene            27300..27449
                     /locus_tag="OE968_001898"
     CDS             27300..27449
                     /locus_tag="OE968_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219178.1"
                     /translation="MVLANVEQVIKLAEKILNKKKCSVNKAIDIVIKILSKYECEGML
                     RNEFN"
     gene            27436..27885
                     /locus_tag="OE968_001899"
     CDS             27436..27885
                     /locus_tag="OE968_001899"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219179.1"
                     /translation="MSLIKYRGYDFENEKWIYSATIMWSNILECLVMLTEGCKWQKVS
                     NVGVCSGEWARNNQEICEGDILKGYDNFHDTSQYGVVKRDIGSIKLYLEWHYLKKLEG
                     EWIELINKTEIYHSRDYKIVGNEYENLEEVRTEFLERKESLENEYLS"
     gene            27988..28164
                     /locus_tag="OE968_001900"
     CDS             27988..28164
                     /locus_tag="OE968_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219180.1"
                     /translation="MDDRLEMINASVNYIQMICESSNIAIIAERGRVRILDLETKEKY
                     DLLKNKLEEMLEEI"
     gene            28274..>28807
                     /gene="dcm"
                     /locus_tag="OE968_001901"
     CDS             28274..>28807
                     /gene="dcm"
                     /locus_tag="OE968_001901"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
                     /protein_id="HCP7219181.1"
                     /translation="MLTFLDLFAGIGGFRLGMEKAGHKCLGHCEYDKFANLSYNAMHK
                     PKEDEWFERDIREIRTENIPRADVWCFGFPCQDISVAGKQFGFRGERSSLFFTVTKLI
                     RELKEEDRPKYLLIENVKNLLSVNGGFDFLKVLVELDEIGYDAEWQVLNSKNFGVPQN
                     RERIFIVGHFRGRSTRKV"
BASE COUNT        11477 a         2966 c         5269 g         9095 t
ORIGIN      
        1 tattatattg tacacttgga ttataactgt agtagtgtat ttaatttaca ctatatttaa
       61 atatataaaa cttaaaaatt taataaatga cttatcttat gatgttgatg atagagagat
      121 tgtaaatctt tataaaaata tattagaaga atttaatata acaaaagata taaaactcaa
      181 atactcttat gaagttgaaa caccagcatt ttttaattca tgtgtacttt tgccaccaca
      241 tgagtataaa ttgaaagagt tagactggat ttttagacat gagcttatgc attttaagag
      301 tagggacctt tatttaaaat atgtaatcct atttttaaaa acagtatatt ggtttaatcc
      361 atttatatat ataatggata aacatataga tttagattgt gaactttatt gtgatgaaag
      421 agttttaaaa aatcgaaatt cagaggaaaa aaaggattat gctttaacaa ttctaaatgc
      481 aatgagaaaa ggttcaaata cttcaaataa atttatagct ggacttcata agcaatctga
      541 tattaaaaag agagttatga atatgtttaa tgaaaagtac aagaatggta tattaatggc
      601 attaacttta tgtttattat cttctattac ttttttgaag gttaattcaa ctagtattgt
      661 taatcttaat gtattaccta aaggatttga agacttacga actgttagca gtatacgttt
      721 ttcagttata ggatttacat atgcagatgc tcctaaaaat atgagggaag aatataaaat
      781 aaattgtgaa tcattaggtt tgatacctaa agactctgat aaaatagaag ttggtataga
      841 atattatgac agtctattga atgattaaat aaatattatt ttaacagata ttaattataa
      901 agttttgaat agtaatttgt tgagaaataa atatatcctt ataaaaatag atacttatat
      961 accaagaata aaaaatagtc aagatagtac acaaggatat acttataaag aacttaaata
     1021 agtgaaataa attattaatt ataaggttta taattttaaa aaattagata aattcaggtg
     1081 taaaatacta taaaacacaa ttcggaaaag tgtatgttga acttcattta aaatggaatt
     1141 tcaaagttgc tatagtaagt agtttaagca ttcttcttat attaatcttt gagaataatg
     1201 tatttaaaaa agttagtaaa aaatttaact attgtatatt aatgatagtt gctattgata
     1261 tattatctaa aaaaattaag tatgaaaaga ttactgctag gacaatcttt tcatacttaa
     1321 tttttaatat ttatattatc caaaattttc atctttttaa cttagaattt gagaatcact
     1381 attaggaaat aggctttgat ttatgtaggg ttaaaaattt cacagaatat ctaactttat
     1441 actaaatcca tcaaaaaata tacgccatac aaaagcgcat aaaaaaacac ataaaacaat
     1501 atttatgcgc actttaacct cgaatggtac aaaattcttt acttttacag acccatatta
     1561 tataattaag taaataatgt atatttaggt gacatattgg ataagctaat ttatttattt
     1621 tattaatata ataatactat aaaagttata taaagtggtt tacaaaaaag ttacagatag
     1681 agcttttatt aatgtattgt gtattagtat tttatcctta ggtacacttc acctacaaaa
     1741 tagaatcata agataattat gggaaaattt taggaggttt atcgtgaaga aaaagatatt
     1801 aataccagta tttgcatcag ttatggcatt atcagtaagt tcaattgtaa atgcagatga
     1861 agtaaatgat tcatctcaaa ataaggatga taaaacaaat actgaattaa atttaggtga
     1921 atataaagaa gtaaaatata aagttgcaaa aataaaagat ggagtagcta taaagataag
     1981 agaagaaggt caagttcaaa acatagctta ttctggagat gaatttacgg ttttaggaac
     2041 tcaaggagaa tgggttaagg ttaaagttga agatggcgaa ggttggttag ctactagata
     2101 tgtagatata tctgaaggtg taggatatac taacgctgat aaagtaaact taagaaaaga
     2161 taagagtgaa agttcagaag taattgaaga gctggaaaaa ggaagttctt tattggtttt
     2221 ggaagataat ggagattggt taaaagttaa agatggggaa acagaaggat atgtaaaatc
     2281 atcttatata tctgataaag ctcctgtaat agaagagcca caagtaaacc caagtattga
     2341 ccaaaatgta gattctacaa ataataatca acaaaacaat gcaaatacta atcaacaaaa
     2401 taataattca aatgtgccaa cagctaactc taatgcagtt caagctgtac ttaacttggc
     2461 atattctaag caaggttgtc catatgtttg gggagcagaa ggaccaaaca cttttgactg
     2521 ttctggattt acacaatatg tgtatagaaa tgcagtagga aagaatatac caagaacatc
     2581 taaagcacaa tctaaatatg gacaaactgt aagtaaagca aatttacaac caggagattt
     2641 agtattcttc acaactaatg gttctggttc tgttagtcat gttggaatat atgtaggtgg
     2701 gggtaatatg atacactcac catcaacagg aaaaacagtt agtgtaacta gtataaattc
     2761 atcatactat acagcaagat ttgttacagc aaaaagaata ttataatcgg tttgtaatat
     2821 gacaaattga taaatacata aatatatata aacgctctat attatattta atttaatcat
     2881 ggaaacaaaa taatgattat attttaaatg tactatagag cgtttttgta tcactttaaa
     2941 tctaatcaag attcaagtta atatgactgt taaataggag ccttttcata tgatgattat
     3001 ttgtgcaatc ccttgacagg atagggtaaa ggtggtaagc tactaacagt acaaaaatac
     3061 ttttaatttt agttcagaga ggctaaaaaa ggaggacgaa agatgttaaa atcaagaaat
     3121 ttaatccaac cagaagactt ttcaatagaa gaaatagatg aaatattaga attagctcaa
     3181 aagataattg acaatccgtc aaaatattct cgtatatgtg aaggaaaact attagctaca
     3241 ttattttatg aaccatcaac aagaacaaga ttaagctttg aatctgctat gaacagatta
     3301 ggaggacgtg tagtaggctt ttcagagcca aattcatcct ctgcatcaaa aggtgaaact
     3361 ctaggagata caatgaggat agtatctggt tatgttgata taatagctat gagacatcct
     3421 caatcaggtg cagcttcaga agcagctaga tatacggaag tgccatttat aaatgcagga
     3481 gatggcaaaa accagcatcc aactcaaaca cttacagact tacttactat aaaatcatta
     3541 aaaggaactt tagaaagcca tacaatagga ttatgtggtg atttaaaata tggaagaact
     3601 gtgcattctt tggttaaggc tatggcaaga tataaaaata caaagtttgt atttatagca
     3661 cctgaagagt taaaaatgcc agattatata aaagaagcta taaagggaca tgcatattat
     3721 gaaactaata atttggatga tgttatagga agcttggatg ttttatatat gactagagtt
     3781 caacaagaaa gatttgaaga taaatcagag tatgaaagac ttaaaaacta ttatatttta
     3841 aataaagcta aattagaaaa ggcgtctaaa gatatgttag taatgcatcc attaccaaga
     3901 gtaaatgaga tagacataga tgtagatagt gatgatagag ctgtatattt taaacaagct
     3961 aaatatggaa tgtatgttag aatggcttta ataataaaac ttttaggtat aaatgaagac
     4021 taatagttat catataatag taaaacaaag gagattttgg gatgtataaa attctggaaa
     4081 atatatatat aggcgaagat atgtatagaa tgaaagtaaa aggtaatttt gaaggtaaaa
     4141 tgggacaatt ctatatgtta agagcatggg atacttatcc agtactttca agacctataa
     4201 gtatacatga tatagatgaa gaagggataa cttttcttta taaagtagta ggagaaggaa
     4261 ctcaaatttt gagtaaccta aaggtaaatg atactataaa attggaaggc ccttatggta
     4321 atggatatgc taaggttgat ggaaaggtag ctctagtagg aggaggaatc ggtgtagctc
     4381 cactatattt ggttgctaaa aatataaaaa attgtgatgc atatcttggc tttagagaag
     4441 atgttatatt agaagatgaa tataaacaag tatgtaataa agtatataca acagtaggaa
     4501 atacttttgt aacagatata attgatgttg agaaatatga ttatatatta acatgtggtc
     4561 caactccaat gatggaaaaa ttagttaaga tggtagaagg tactaaaacg agaattatgg
     4621 tatctcttga aaaccatatg gcttgtggag taggtgcctg tttagtatgt acgtgtaaaa
     4681 ctaatggagg aaataaaaag acttgtaaag atggtccagt gttctgggga gaggacgtga
     4741 tttttaatgg gtaatttaag tgtgaaattt ggaagtgtag aatttaaaaa tccagtaata
     4801 atggcgtctg gaacttttgg atttggaaaa gaatataatg agatttatga tatacaaaaa
     4861 cttggtggta taagtagcaa gggtcttact ttaaataaaa aacctggtaa caatggtatg
     4921 agagttcatg agacaccatc cggtatgatg aatagtgttg ggcttgaaaa ccctggagtt
     4981 caaggattta tagactatga attacctttt tttagtaaac tagacttagt cagaatagct
     5041 aatgttggag gtgggacatt agaagactac ttattagggg ttcaaatgtt aaatgacaag
     5101 cctatagaca ttattgaatt aaatatatct tgcccaaatg tcaaagctgg tggaatggct
     5161 tttggtataa aaaatgaagt ggcaagagaa gttgttcgtg aggtaagaaa cataacgaaa
     5221 ctgcctttag taataaaatt atcacccaat gcagaagata ttgtaggaat ggcaaaagtt
     5281 tgtgaagaag aaggtgctga tggagtttca ttagttaata cttttaaagc aatggcaatt
     5341 gatataaaaa atagaagacc agtatttgaa aatgtatatg ctgggttatc tggaccagct
     5401 ataaaaccta tagctttgag aatggtacat gaagtgtgta aaaatgtaaa tatacctgta
     5461 atgggaatgg gcggaataac taaagccaca gatgctatag agtttataat ggcaggagct
     5521 acttgtatcc aagttggaac tgcaaatttt atgaatccta gaataggtat tgaaataata
     5581 gatggaatta atgaatttat ggatagagaa ggaataaaaa gtttagacga aataagagga
     5641 attatataag gtagaataaa tagtatttta aagataaaaa atatagatta aataaacaat
     5701 aattttataa cattaacatg gaggaaaaat aatatgagta aagtagatgt agtggatata
     5761 ttaaagaaaa gtgatgcatt gttggaggga cattttttat tatcttcagg aaaacacagt
     5821 aatagatacg tacaatgtgc aaaagtatta agatttccag aatatgctgc tgaggtatta
     5881 agtacagttg ttgaacaaat aaaagactta gatatagact tagtagtagg accagctatg
     5941 ggtggagtaa tagtttctta tgagttagga agacaattag gaaaagaagc tgtatttact
     6001 gagagaaaag acaatacaat ggagttaaga agaggatttg aagttaaaaa aggagcaaag
     6061 ataataattg ctgaagacgt tgtaactact ggtaaatcaa ctatggagac aaaaagagta
     6121 ttagaagcct taggtggaga agttgtaggt gttgcatgta tagcagatag aactaatcat
     6181 gatataggta tgcctatata tagtgctata aaacttgata ttcaagttta tgaatctgat
     6241 gagtgtcctt tatgtaagga aggaaaatta ccagttgtta agcctggaag tagggagttc
     6301 aaggaattag ggatgtaata aaaacttaat tatttatagt gttacttaaa aaatgtaaat
     6361 tttttagagt aaaaatttgt aatataacat ataacttaaa aataaaaagc agttagcctt
     6421 ataaatgaag gttagctgtt ttttttgtta aaaatatatt tacaaaataa gagatagtag
     6481 cagtacaata taagtataag gtaaaagtat tatatattag ggaggggtaa gtatgaaaaa
     6541 tcaattaaat gaaaatcata aaaaggttgt attttttgga gtaggtgctg taggagctac
     6601 ttttgcagaa caatttttta actctaaata tgattttaaa attctttgtg ataatgaaag
     6661 aaagaaaaga tatttagaag aaggatttat aataaatgga aaaaggtatg attttgatta
     6721 tgtaactaaa gatgagtata aacaagaggc tgattttata attataggtc taaaatataa
     6781 taatttaaaa gaaaatataa aagaattaga tggattagtt ggaaaaaata cagttataat
     6841 gtctctgcta aatggagttg atagcgaaga gataatagga gaaagatttg gaattgaaaa
     6901 aatggtatat tcatatgtta ccaatataga tgcaaagaaa atcaataata atattataca
     6961 cactactaat gggataattg tatttggtaa caaagataat agtgaagata gaaaaactaa
     7021 tataataacc gaagtctttg atgatgtaaa tatagaatat actttatcaa aagatattca
     7081 acgagatatg tggtggaagt acatggttaa tattggtgta aatcaaactt cagctatact
     7141 tggtgcacct tatggagttt ttcagagttc tgagcattta agagaattag caaaatctgc
     7201 aatgagggaa gttgttgcta tagcacaagc aaaagacata tctcttacag aagatgatgt
     7261 ggaacattca ttacatagaa tactagaaca ttcaaaagaa ggaagaacat caatgcttca
     7321 agatgtggaa gctcatagac ttacagaagt agatatgttt tctaagaata tctgcaaact
     7381 tggaaaaaaa tataacatac ctactcctat aaatcagact ttcttttata tgataaaagt
     7441 aattgaaagt agattttaaa gggtctttgt aagaaatatt gataattatt gattttaaat
     7501 tttattaatg ttatatacta tttaagttac taaatatttt taactcttca atgaaaatag
     7561 ttgctgcttt tgataaagtt atatcttttg gaaatatata tgagaaatgt ctgttgtagc
     7621 tgcttccaag ctctatgaca gacagctcat tgtttagaac aggtaagctt gtcactagat
     7681 tagagactat tgtaattcct aaattatttc taacagattc tttgacagca taattacttc
     7741 caaaaaccat catacttttt ggaataattt ctttaacact taaaaacata tctaaataat
     7801 ctctggttcc agaaccatcc tccctgacta tccatttttg gttttgaagt ttatcaaaac
     7861 taaaatcttt taataaatga ctcttgtatg gaagtgctaa aaccatctta tcttcaaaaa
     7921 aatattcttg aataaatgaa ggggaagagc aagtgccttc aataagacca atgtctaaaa
     7981 tataatcctt aacatgagaa gatacgattg atgtattttt tataaaaact tctacatcta
     8041 tgtcaggata ctttttagaa aataatgcta gaaaatttgg taaaatatac tctccaatag
     8101 ttaaacttgc accaatcttt aagtgaccag ttatagcatc tgaaacttgg cttacatcat
     8161 gataagtaat atttaaaaga tttaatattt ctttagctct tttgtacaag atttgtccac
     8221 tttctgttat aaaaatggtt ttttgtttaa tagacctgtt tataagcaca actttaaaat
     8281 aattttctag attttttatg tgtttactta cacttggttg tgatagattt aaatattccc
     8341 cagctttagt aaagtttttg tattcaacaa cagctacaaa tgtttttaat tcttcaaaca
     8401 attttttgtc tcctttacct aatgaaattt tacatttttt atatactttc tacagataat
     8461 tatactatat ataataacca ttaaaaacat taatcattac gatattatat atttatttta
     8521 cttatggtta ttacaattat atactattgc tatgaagaaa actatattaa ttataaggta
     8581 ggtatattat gttaaagaaa aaaagcagtt tgacattaaa aactataagg gaaatattac
     8641 caggactgtt tgtatcagta ttagtaggtt atattagtat atttatttct attttaattc
     8701 ctaaggtagg ggcagcatca atttctatat ttttaggtat gtttgtagga aacctatttt
     8761 taaatcaaaa ggtatttcaa aaaggttata aattttcaga gacagatttg ttatcatatt
     8821 caatagtact attaggagca acactcagtg tatctacctt aatagactta aaagtttcag
     8881 gaattttatt tataatattg caaatgacaa taacaataat agctgcactt tatataggta
     8941 aaaaactagg atttgaagaa aactttagat ttctaatggc aagtggaaat gcagtatgtg
     9001 gttcttctgc aataggagca acagttccag tggttaatgc gacagataaa gaaaagggaa
     9061 ttgcagtaac tattgtaaat gttactggta tatttcttat gtttttactt ccaataatat
     9121 ctcaattttt atatagccat gaacttgtaa aaacttcagc aatgataggt ggaactttgc
     9181 aatcaattgg tcaggttgta gcaagtggag caattgttgg agaaaatgta aaagatttag
     9241 ctactatttt taagatagta agagtaatat ttctagttgt tgttgtatta gtatttggac
     9301 atatgaaaaa tcaatctaat agggaaattc ttgaagaaga aaaggatgag ataaaaaaga
     9361 aaaaagtgac tataccatgg tatgtaattg gattctttat aacttgtgca cttttttcaa
     9421 tgaacattat accacaagaa gtatctgtgt tgtgcaaaga aataagtaac aaactagaaa
     9481 taatagcttt agcagcaatt ggattaaagg ttaatgtaaa agatttagtg aaacaaggga
     9541 aagaagtttc tttatatggt ttatttgtag gtatagtaca agttgtatca gctgtagttt
     9601 taataaaaat atttatatag cataaaaata gtatttgtaa tattaatttg attaattaaa
     9661 ataatatgat actaataatt tataatataa ataaaaaatg aatttcgata agtttaagtg
     9721 ggtataaact tatagaaatt cattttttat ttaaggtaaa aatttaaagt aaaatattat
     9781 tttacataat aataacctta taaattttga aattacttat ctttgtgtta aaataagtaa
     9841 aatgcacata ttagagctaa gtttttaagt aaataaacaa aatgaaaata taaatattaa
     9901 ggagatttgg tatatgaatg tttatgaaaa aggtaatgga gttatactag aaggagtaac
     9961 agattttgac ccagtacata tatttgagtg tggtcaatgt tttagatggc acaaacaaga
    10021 agatggctca tacactggag ttgcaaaggg gagaatatta aatgtcaaaa aagagaatga
    10081 taaaatatat ttaaataata ctaatttaaa ggagtttaac agcatttggt ataattactt
    10141 tgatttagga actgattata cagaaataaa gaataagcta aaaaatatgg atgaatattt
    10201 aaataaggct actgaatttg gatggggaat aagaatatta agacaagatg gatgggaaat
    10261 gcttatatca tttataattt cctctaataa taggattcct atgatacaaa gagctataga
    10321 aaatttatca agaaaatttg gtaagtatat aggtgaatat gaaggtaatg aatactatgc
    10381 attcccaaca ccagaagaac taaataaggc ctcacaagag gaaataagag catgtcaaac
    10441 aggttttaga gataagtaca taaaaagtac tacacaggca gttatagaga ataatgatga
    10501 ggtatctgaa tatacaaatt taagtactga ggattgtaga aaagagcttt taaaatttaa
    10561 tggagtagga ccaaaagtat gtgattgtat tgcattattt ggtatgcaaa aatatgattc
    10621 ttttccagtt gatgtttggg ttaagagagt tatgcaagaa ttttatatag atgaagacat
    10681 gagtttacct aaaatgagaa cttatggaat cgataaattt aaagaaatgt ctggatttgc
    10741 tcaacagtac ttattttact atgcaagaga actcggtata ggaaaataaa ttaaggggga
    10801 gaaattatgg gagtaatagg aacaatattt ctgttctatt taattatatc atatctagct
    10861 ggagccataa tttctgtgat tatattgctt gaaaatagag accctgcaaa aacaatgtct
    10921 tggctattga tgtttattat atttccaggt gtaggtttaa tgatatatgc tatttcaggt
    10981 agaaatatta gaaaaagaaa attatttaag actcaaaaac tagctaataa tataaaagaa
    11041 aagaaactat ttgatacatt agaaaagata acagaaatag ttgaattaga aaaagaatct
    11101 ataaaacaaa ataagctttt aagagatgaa gaggatggta gttatagaaa aagggtaata
    11161 aatatgttgt taaagactgg tatgtttccc tttactaaaa ataataaagt ggatgtattt
    11221 gtagatggaa atgaaaagtt taaaagactt atagaagata taagagaagc caaagaccat
    11281 attcatttag agtactttat catcaaagat agtgaaatag gtagggtgtt aaaagaagaa
    11341 cttataaaaa aggctaaaga aggcattaag ataagaattt tatatgatga tgtaggatgc
    11401 tggagatttt ggtttaatag aaaatttttc cgagaaatga gggaagtagg tatagaaatt
    11461 gcagcatttt tacctacaaa atttcctata ataggaggga aattaaacta tagaaatcac
    11521 agaaaaattg ttgttattga tggaataatt ggatatacag gtggaataaa tataggagat
    11581 gaatatttag gcaaaaatga taagtttgga tattggagag atactcatat taggattaag
    11641 ggtatttctg tatacatgct tcaaatgaca tttctgattg attggtatta tacgacaaaa
    11701 gaagtattag tgactaaaaa ttatttccca agtgtaggga atgttggtga aagtatgata
    11761 caagttgttg cgagtggtcc agacagtgac tgggaagata ttcattatgc ttatttttct
    11821 gcaatatgtc aggctagaaa aaatgtttat atagaaactc catattttat tccagatgaa
    11881 agtctactaa aagctataaa gagtgctgct cttagtggag ttgatgtgag aataatattt
    11941 cctaaaattg cagaccacaa gatagtaaat atagcatctt attcatattt tgaagaaata
    12001 ttaagagcag gtggtaaagt ttatttatat aataaaggat ttatacattc taaagtcgta
    12061 ataatagatg ataaaattgc ttctgcaggt acagctaata tggatttaag aagttttatg
    12121 cttaactttg aggtaaatgc atttatctat gatgaagaag ttattagggt aatgacagat
    12181 gatttctttg aggatttaag tcactgtgaa gaacttaatt tggaggtatt taagaataga
    12241 aatatcatac aaaaaatcaa agaatctgta gcaagattat tttcaccaat attataaaaa
    12301 attattaaaa aaggtattga aaattatgtg tgattggtat attataataa ttgttagcac
    12361 tctattagat agagtgataa taaataaaaa gtatatatat aaatctacat atataagtag
    12421 tattaattta aaaataacta aaaacatagg cgaactagtc tatacttaat attttaggag
    12481 gcgtgaataa tgaaaataag accattagct gacagagtag taattaaaaa agtagaagca
    12541 gaagaaaaaa ctgcaagtgg aatagtttta ccaggagcag ctaaagagca acctcaaata
    12601 gctgaagttg tagaagttgg accaggtgga atagttgaag ggaaagaaat aaaaatggaa
    12661 ttgacagtgg gagataaggt tatattccaa aaatattctg gaacagaagt taagatagaa
    12721 ggacaagaat acacaatact aagacagagt gatgtattag ctgttattga ataaatatag
    12781 aataaattta ttaggagggg tttaaaatgg ctaaagaaat taaattttca gaggaaacaa
    12841 gaagagcttt agaagctggt gtaaataaat tagcagatac agtaaaagta acattaggac
    12901 ctaaaggaag aaatgttata ttagataaaa aatttggttc tccacttata actaatgatg
    12961 gagtaactat agcaaaagag atagaactag aagatagatt tgaaaatatg ggtgctcaat
    13021 tagttaaaga agtagcaact aaaactaatg atgtagctgg agatggtact acaactgcta
    13081 cagttttagc acaagctata ataagagaag gtttaaagaa tgtaacagca ggggctaacc
    13141 caatactttt aagaaaagga atacaaaaag cagtaacagt agcagtagaa gaattaaaaa
    13201 atcaatcaag aatagtagaa acacaagagg ctatatctca agttgcttct atatctgctg
    13261 gtgatgaaga agttggaaaa ttaatagcag aagctatgga aatagtaggt aaagatggag
    13321 ttataactgt tgaagagtct caaactatga atactgaatt agatgctgtt gaaggtatgc
    13381 agtttgatag aggatttgtt tctgcatata tggttacaga tgtagataaa atggaagcag
    13441 ttttaaatga cccatatata ttaattactg ataaaaaaat atctaacata caagaattat
    13501 taccagttct tgaacaaata gttcaacaag gtaaaaagtt attgataata gctgaagatg
    13561 tagaaggtga agcattatct acattagtag taaataaatt aagaggaaca tttgatgtag
    13621 tagcagttaa agctccaggc tttggagata gaagaaaaga aatgcttcaa gatatagcaa
    13681 tacttacagg tgctcaagta atatcagaag aattaggtta tgatttaaaa gaagctgatt
    13741 tatctatgct aggtagagct tcatctgtta aggtaactaa agaaagtact acaatagtag
    13801 atggttctgg agataaaaaa gctatagaag atagagtaac tcaaattaaa catcaagtag
    13861 agcaaactac ttcagatttt gatagagaga aattaatgga aagattagct aaacttgctg
    13921 gaggagtagc tgttgtaaaa gttggagctg ctacagaagt agagttaaaa gaaagaaagt
    13981 taagaataga agatgctctt aatgcaacta gagcagctgt agaagaagga atagtagctg
    14041 gtggaggaac tgcttttgtt agtgttatac cagcaatagg aacactaatt gagagtttag
    14101 aaggagaagt taaactaggt gctcaaatag ttaaaaaagc gttagaagag ccattaagac
    14161 aaatagctat aaatgctggt cttgaaggtg ctgtaattgt gcaaaatgtt gttaattctg
    14221 aagcagaaac tggatttgac gcattgaatg aaaaatatgt aaatatgata gaagctggta
    14281 tagttgaccc aactaaagtt agtagaagtg ctttacaaaa tgctgcatca atagcaagta
    14341 ctttcttaac tactgaagct gctgttgctg accttcctga aaaagaagat gtaggaatgc
    14401 caggaatggg tggcggaatg cctggtatga tgtaatttaa aaaatttaaa atataaattt
    14461 taatataaag aactatttcg acttagattt taaactctaa gttgaaatag ttcttttgta
    14521 tatatctaat ttttgtatat ctataaattc aatacacata tttagataat cagtatctag
    14581 tttgtaataa tattttagag tagtattgtt attttttagg ttatgatttt agatatatat
    14641 taattaaggt ataattgttg atagagaata aatcaaattt aaaaggatgc gataatatgg
    14701 acttaagaaa attgcttgaa gaagttaaaa atgaaaatat tgatatagat tttgcgttag
    14761 aaaagttaaa agatttacct tatgaagacc ttggatatgc aaatatagac catcatagag
    14821 aattaagaaa tgggtatccg gaagttattt attgtgaagg taagagtgat gagcatattt
    14881 tagggattat tgataaaatg aatcaaaaaa gttctaacat attggggaca aggtgcagaa
    14941 aagaaacttt tctgaaaatt aaagaaatct ataatcatgc tgagtacgaa gaggcgtcta
    15001 aaattcttaa gattcaaaat catgatatag agaatatagg aaaaggtaaa attgtgattg
    15061 ctacaggggg aacttctgat ataccagtag cagacgaagc ttatcataca gctaagtttt
    15121 taggtaatga tgttgataga atatatgatg ttggagtggc aggtatacat aggcttttaa
    15181 ataaaagaca taaaatagat agtgctagag taatagtagc cgttgcaggt atggaaggtg
    15241 ctcttgcaag tgtaattggt ggactggttg atgttccagt aatagctgtt ccaacttctg
    15301 ttggatatgg agcaaatttt ggaggattag cagcattact agctatgtta aatagctgtg
    15361 catctggaat atctgttgta aatattgata atggatttgg agcaggatat ttagcatcaa
    15421 tgataaataa actgtaaata cattgatata aattaaacaa aactatataa taaaatttaa
    15481 tttctattat atttttacta ttaaaattga ggagacatat atgagtgaaa aaatacttta
    15541 ttttgatata ataagcggta tatcagggga tatgaccctt gcaagtttat taaatttagg
    15601 tgtgcctaag gaaatttttt tggaggaaat tcataaacta agaatgagcg atgaatttaa
    15661 tataaacatc agctcgaaaa ctgaaaatgg aatagtaggt acaaaagtag aagtaattac
    15721 aaaagaaaaa catacacata gaaatttagt ggatatattt gaggttatag ataaaagcac
    15781 tctaaacgaa aatgtaaaat ctaaagcaaa aaaaatattt atggtaattg gagaagcaga
    15841 agcaaaagtt catggaacta caatagacaa gatacatttt catgaggtag gggctataga
    15901 ttcaattgta gatatagtag gagcttctat attagttgac ttactttgtg tagataaagt
    15961 ttgtgctagt acagtgtctg ttggttcagg atttgtaaaa tgtgaacatg gaattatacc
    16021 tatacctgca cctgcaacta tagaaatttt aaaaggtgtg ccaattaaat taaataatgt
    16081 aaatggagaa tgtacaactc caacaggagc tgcaatcata aaagtcttgt gtgatgagtt
    16141 tgtagatgag cttgaatttt ctccaaagca aattggatat ggtataggtc ataagaagtt
    16201 tgaagtacca aatatactca gaactgtatt aggtgaaaaa aaaaagaaga attaatttat
    16261 gaaattagtg caaacattga tgatatgtct tcagaaatct attcttattt gtatgaaaaa
    16321 atattagatg agaaagcatt agatatttat acagagagca tttatatgaa gaagaataga
    16381 ccagcaacaa aagtatcaat tttatgtaat gaatcagatt tagaaaaatt tattaaaata
    16441 ttacttttag aaactagtac ttttggagtg agatataatg catataatag agaaattcta
    16501 gagagaaaat ttgtaaaatt agatacaaaa tatggagtgg ttacagtaaa actagggtat
    16561 tataaaggaa aactagtcaa ggctactcca gaatataatg aatgtaaaac tatagcaaaa
    16621 aatgaagata ttcctataaa aaaagtgttt gctgatataa attttagaat aaaagaagaa
    16681 tttagtgaaa acttattgac ataagtaata aattttgata aattaatatt cagccttatt
    16741 aaataaaagt aaacagaaaa aaatatataa aatataaact cactcgtata tgctcagaaa
    16801 tatggtctga gagtctctac caagataccg taaatatctt gactatgagt gaaattatta
    16861 taccaaaaga cctagttaag taaatgtgta ggctgagtta aactccctat gtgttggcta
    16921 taagataaag gtattttgga agcctgtata gtaatttcac ttttgctaga aattatggaa
    16981 gttactatac aggttttttg tgtaaaaaga tttaatataa tttagactgt attgtgttaa
    17041 aataaatata taaaaactat attatacaag gagagatgta aatttatgaa acatgaatta
    17101 gtacttgtaa tagattttgg aggacaatat aatcagttga tagctagaag agttagagaa
    17161 aacaacgtat attgtgaaat acttccatgt actgcaagca tagaaagaat aaaagaaaaa
    17221 aatcctaaag ggataatatt tacaggcggt ccaaatagtg cgtatttaga agattctcca
    17281 acaatatcaa aagaaatatt tgaactagga gtaccaatac ttggaatatg ctatggtatt
    17341 caaataatgt ctcatgtatt gggtggagtt gtaagaaaag gtaataaaca agaaaaagaa
    17401 tatggaaaaa cagctataac ttatggaaaa tcatcattat ttgaaggaat aactacaaat
    17461 agtgtatgga tgagtcatac agatttaata gaaaaagttc cagaaggatt tactatagtt
    17521 gcaaatacta atgattgtcc agtagcagct atggaaaatg tagaacgaaa cctatatgga
    17581 gttcaattcc atccagaggt agaacactgt ttggaagggg acaagatact tacaaacttc
    17641 ttatataata tttgtaaagt aaaaggtgac tggactacag attcattcat agaagataaa
    17701 ataaaagaat taaaagaaaa aataggcgat aaaaaagctt tatgtgcttt aagtggagga
    17761 gttgattctt ctgttgctgc agttcttatt cataaagcaa ttggggacaa cttaacttgt
    17821 atatttgttg accatggttt acttagaaaa aatgaaggaa atgatgtaga aagaatattt
    17881 agagagaaat ttgatataaa tttaataaga gttaatgcag aagatagatt cttatctaaa
    17941 ttaaaaggag tttctgaacc agaagctaag agaaaaataa taggtgaaga atttataaga
    18001 gtatttgaag aagaatcaaa taaattagga aaaatggatt tcttagtaca aggaacaatc
    18061 tatccagatg ttatagaaag tggacatgga aatgctgcta ctataaagtc tcatcataat
    18121 gttggtggaa tcccagaaga tgtagacttc caagaaattg tagaaccatt aagagagtta
    18181 tttaaggatg aagttagaaa aataggatta gagcttggta tagaagaagg attaatattt
    18241 agacatcctt tcccaggacc aggtctagga ataagagtta taggtgatgt aactaaagaa
    18301 aaatgtgata tattaagaga agctgatgct gtttatatgg acgagcttag aaaagcaggt
    18361 ttatacagag aaatatggca agcttttgca acattaccag atgttaagac tgttggagtt
    18421 atgggtgatg aaagaacata tgcttattta gttggtttaa gagcagttac ttcttctgat
    18481 ggaatgactt ctgactggta taagatgcct tatgatgtat tagaaagaat ttctaataga
    18541 ataataaatg aagttgatgg agtaaataga gtagtttatg atataacttc taaacctcct
    18601 ggaactattg aatgggaata gtaaataaaa aagtcgtaag ccttgtattt tcaaggtttg
    18661 cgacttttaa aaaaatcttt gtgatactaa aatgatacta tatatttaaa ttatctagtt
    18721 tttgggcaac ttcaagttgc ttatttgggt ataaatgtga atatgtattc caagttgttt
    18781 ctactttttc atgccccaat ctttctgcta tagttaatat atttacatcc atatttacca
    18841 ataatgacgc atgagaatgt ctcaaatcat gcactctaat tctttttaca ttagataact
    18901 tacagcatct atctagctct ttagaaagat aacttttagc aaatttaaat attctttcat
    18961 tatcttttaa gtcatatagc ttagatagat aatcttttat attattatat aagaaatgtg
    19021 ggatagggac aacacgttta cttttaggag ttttaggaga agaaacaata tcctctccat
    19081 ttagtcttat gtagcttttt tcgacgctta ttttattttc gaaaatatct tttggagtaa
    19141 gagctaacaa ctcccctagt ctaagacctg tccaaaataa aatttcaaat gctagtctag
    19201 gttctgattt cttttcaaat tcaataaatt ttttaaactc ttctaatgtc caaaagttca
    19261 tttcatctgc gtttttttta ccgatagaac ctgccaaatg agcaggatta gaaggtaagt
    19321 tataatattt aactgcataa tttaatacag caacaagctg gttgtttatc gttttaatat
    19381 atgtttggct ataatcactt tttaataatt cgttttgcca tcttcttata tgtgttgcag
    19441 taatttcatt tatttttaga cttttaaaaa aaggtaaaat tctaaagttt attaaatact
    19501 ttttagtttc taatgtagat aattttaatc tagaagacat atcgtgcatg tattcttcta
    19561 tgagactttc aaaactcata tcagtactca ttttagattt attcaaaaat tctctttcaa
    19621 actctagagc ttctttttta gttttaaaac ctctcttaat tttctttttc ctatccccat
    19681 cgaagtctgt aaaataaaag ctagcatacc aactttttct ttgttcgtct ttgtaagcag
    19741 gcattttaga cacccccaat tatgtcattt taatattaca ataattataa catgttagat
    19801 atgctatcta aataattgtt ttattttcct cttcttttta tttcttgaag cttgtaatat
    19861 ttacacagtt ctaagaagtc ttcttctagt gctatagata agtctaatat cgtagatata
    19921 cctatatctt tgtactcttg attttctagt tttgatatat aacttctgtt acgtctcatt
    19981 ttttctgcta attctagttg tgtcattctt ttcttttttc ttaatttttt caacatttat
    20041 taaaatccac cttttaatta tttttatgac atttttataa ttaatagttt gtgtaatttc
    20101 ttgtaaaaaa tgttcctcat tagaacattt tttggtggaa aaatgtgtta aaatgtaagt
    20161 aagaaaagca ctttcaaagc actataaaaa tagtgctgaa atagataaac aaataaaagt
    20221 aataaggagg aaagatagat tctagaggga aatcattatc atttttaaga acgtatgttc
    20281 ggttggtggg atagaaaaat actttacagg ggatggttta tttgaatgag aatgaaaata
    20341 tgagtttata tgtcagtaag ttaaaagaag tattgaaaaa taattcagaa gagtataaaa
    20401 aaataagagc taaaataaat gaaatttata atctaaatga aaagaaagaa taaaagggct
    20461 ttagctcttt tattctttct tagtattaac tgctttataa taagcattat ctatcatttt
    20521 ttttattgca tttttatcat ctgaatctaa agatgctaat ctatttatta gttcgttaac
    20581 ttcattatct tcttttgagt taactttttt taataattca tcatcttgtt gagtgttagg
    20641 ttgtatttta cctaatttag ttaatagctc ctttaaagtt aaatttaatc caaaactcat
    20701 tttttcaagc atatctaaag taggttcaac agctttacca ttccttgggt ctctgttttt
    20761 ttctatctta tctatatatg tatggctcac accacaaaga ttagaaaatt ctctaagaga
    20821 taagttatgt tcacttctat attctttaat aatttctgct aatgtttgca taatttcaca
    20881 cctcatctaa gtaatagttg acttaattat atcagaaaaa tgtaaactat tgttaacaaa
    20941 aataaaaatt tagtaaaaaa taattgacaa gagtaaaaaa aagacgtata ctatgattaa
    21001 caaaaaggtt ataaataaag ttaggaggga ttaatataaa aaataattta caatatatta
    21061 gaaaagaatc tagaatatca caaaaaaaat tcgctgataa gataggtata tcaagaccgt
    21121 atttatctag aatagaaaac ggtaaggtta atccgagttt agaaatagcg cataaaatct
    21181 cgctcgaaac agggaaaaca ataaatgaaa ttttttttga ttttactgta aatcatagta
    21241 aactataagg ttttaattgt accttgaaaa ctaaatataa aatattttaa aggagcaagt
    21301 atatgaaaaa taaagaaaaa gaaataatca ttagaggaat tttaatagga attttttatt
    21361 ttttaggaat tgtatttagt aatacttttt ttaaataata aatagaaggg gtaggtgaaa
    21421 taccaactcc ccaaatcaaa ataacacttt ggaagttaaa tataaaatat tcaaaagagg
    21481 tgattagatg caaagagagc aaacaacgct tcgtatacca gaagacttgc acaaagcgtt
    21541 gatagattta agcagtgata taggaatgcc tattacatct attataataa ttgcatgttg
    21601 gttgtatata tcaaagataa attaaccaat ccgatatgca aaatgaatgc acaacattat
    21661 ttattagaga attgattgat aaattatttt ctttagctgt tttctctagc aactctttta
    21721 ggacaccagg aatcctaaga gtagaacgaa cagtatcatc acttttatac gagattgatt
    21781 gaagttcatt aacttttgaa tttctaataa tatcattaat agcgtataga ataagcgaag
    21841 atttgagaat gcctgtttga taagaaattt tttctaaatt ttcatttaat ggtgtatata
    21901 ttcttacagt aatagtagtc attttgacac ctccctaatg acattataca aaaaatattt
    21961 aaaaaagtct tgacactaaa atagtgtcat aatataatga ttatagacag taaaacagtg
    22021 tcataaggag ggaggaataa gaatggaaaa agtaagaatg acagtaaggc tcgtcccaaa
    22081 attaaatcaa tatgtacaga atatagccaa agaatgtgga aaaagtaaaa attctattat
    22141 tgtggatgca tgttgggagt ttattgagaa aataaaaaaa gaaaataaat tcaatgtaga
    22201 aagcgaggaa taaatatgaa taatctacag atatttgaaa aattggaatt tggacaaata
    22261 agaatggcag agattgataa taagccttac tttgtaggaa aagatgttgc aaagtcatta
    22321 ggttataaaa atactaatga tgcaatttta agacattgca aaggggtagt gaaacacgag
    22381 gggtttaaaa ttaatggtat taagattgct ttgataactg agggtgatgt ttatagatta
    22441 atagtaggtt caaatctacc aaatgcagaa aagtttgaga gttgggtgtt tgatgaagtg
    22501 cttccaagca taagagaaac aggtcaatac caagcacaac agcatgtaat aacagaactt
    22561 acaggaacta taggagactt aaaaggaaca ataaaagaat ataaaaagtt gtgtaagata
    22621 acatgctcta agaaacaaca gtattctaaa tacataaaga atagactgga tatagacaaa
    22681 gctaataaag aatacaacca agtgaaagca aggctattcc taattcttgg agttgagaag
    22741 tgggaagaca tagacttcga tacatctaat aatttaatac aaattataga tgattgtata
    22801 agagttataa agtcagagag accatacaag cagttgagtt attttgaaaa ctaaatacag
    22861 aatattttga aatatattgt tttaattaat tattaactag gaggttaaat acatgaaaaa
    22921 taatataagc gattcaagag taaaatattt ttgcaagtgt ccatactgtg ggtttgataa
    22981 tgaggtagaa gttaaaaaag gattgaagcc taaaatatgt tgcatatgta caaaagaagt
    23041 tgagtatgaa aaactggagc aacaaagtac tccagcaaaa taaaattaat aaatatgaat
    23101 atttttacaa gaatctaatt ctttttctaa cttattaaca gcatggttat attgcagtgc
    23161 ctgttctgct ataaagttag aatttgatat gtgttcttta cacatagggc atggtagccc
    23221 attatcacaa acttccctaa atttagattc tgttatggta acttttgtac cacaatcgaa
    23281 acaagtagct tcaattttag ttattttacc gatattcata aatcaccacc taatcatata
    23341 tttataggat ttatcctaca aatatagtat atcaaaggag ggaaataatg gcaattaatg
    23401 acaacataaa taaaatttta agagatagaa atttaaaagc gtggaaatta gcaaaagaaa
    23461 taggcgtaga ttcaggaaat ttatatgcaa ttttaagagg agaaaataaa aatccaacta
    23521 tagatacatt gataaaacta gctgactatt tagatgttac attagacgaa ttagttggaa
    23581 gatagaaatt aaatacagaa tattttgaaa gtaggtgtat tgtatggcaa aagcagtagc
    23641 taaagaacaa ttgttttata gggcaaaaga tatagctaag attttagatg tatgtgaagc
    23701 aaccgcttat aaaataattg gagaattaaa taaagaatta gaaaaagaag gttttaagac
    23761 tttttctggc agggtatcag ttgcttattt taaagaaaga tattgttata agccaagaaa
    23821 gggggtgatt tagttgaatg taaaaggtac taatagctta tatacagttt tgcaatgata
    23881 agcaaataaa agcaagtttt gaaggtctta gaaaatacaa cagagatata gagttagtta
    23941 acttgtattt accaagtaaa ttaaaaataa ataaggaggt ctaattgtat atggtattta
    24001 atttagagaa gttcaaagtg ggaaatgcga taagaataag ttgtgaaaga tttggttttg
    24061 aaattgattg tattgtagta gtagcaacag aaaaagaatt aaatttagca tactttgatg
    24121 aaggtagagg ctgtatggag tatcaagcct taataacaga agatattcaa gatggtgatt
    24181 atgagattaa aattttatct taggaggaaa taaaatggca gctttaataa tggtaggttt
    24241 atttgcaata tgtttagtag gattagtaca aaatagagat taagtgaagg ggtgtattta
    24301 gatggaagca gctagattaa tagcaatggg tcaaattaaa caggctgaaa aagaaataag
    24361 taaattgcaa ggtacaaaaa acaatagtag tttaatgtgg tgggaagccg taaaatttgc
    24421 tagtcaaaat atattacaag ggttggaaca tgatatagag ctagaagcat caactgattt
    24481 cagggagttt atgataacac aagaagaact tgaaagagat agacctatag atgtgcagat
    24541 ataagaaaag agcctagggt gaggctcaat tcaaataaat attaaaaaat ttaattaagc
    24601 taattatagc ataaacggag ggaaattatg agtactttat atgaattaac tacagattta
    24661 ttagaaatag aagaaggttt aacagaaaca acaggaaatg aagctgaaaa actagaggaa
    24721 ataaaagaaa taataaaaca agagatacaa aataaaaaca ctaggatagt ttcagtaata
    24781 ttaaacattg acagtgatat aaactctata gattcagaga ttaaaagatt gcaagagtta
    24841 aaaagggtca aaaagaatac tcttgataga ttaaaaagca atataaaaga ctgtatggaa
    24901 ttacttggta ctaaaaaagt agaaacagtt ttaggaaata taagtataag aaagtcagca
    24961 ggtagcttag tcatagaaga tgaagaaaag atacctgcta tatataaaac agtagagcaa
    25021 gttgtaaaag tagataagaa taccattaaa gattttatta aaaaaggtca tgaggttgaa
    25081 ggttgcagga ttgaatatgg aactacacta acaattccaa aagctaaaaa agagtaggtg
    25141 aggaccatgg aaattaataa tatttacatt aaattgatgg atgtaagagt taaatttagt
    25201 aagttgaatc taaagaaaag tggagaaaat aagttcgcta acttcaagta ttttgagtta
    25261 gcagactttc taccacaagc aactggatta cttgaagaag ctaagctatg ccctatagtg
    25321 acctttacaa atgaatatgc aactctaaca ttaattaatg gagaaaaccc atcagaacag
    25381 attgtattta cttctcccat gagagattta caacttaaag gttctaatga attacaggca
    25441 ctaggaggta tagaaaccta tcaaactaga tatttgtata ttcagttact aaatataact
    25501 gaaaatgata gttttgacgc agtaagtgga aaagaggaat ctaaaagcaa ttctaataac
    25561 aatgttaaac aaagtaacag aatattgact gataaacaac taactagatt atatgcaata
    25621 gctaatagtg ttggagttaa taaagcatta ttaaaagaac aggtttttaa acagctagga
    25681 aaagatataa aggatttaaa taagagtgaa tatgatgctg tttgtgcagc atatgagaaa
    25741 caagccttta agggtgcata acaggaggtg atagagtggc agttttcaga cagatatata
    25801 caagcttttg gactgaccca aaggtacaag aggagtggac accagaagat aaatttttct
    25861 ttatacttct tcttagtaat cctcaaacaa cacaaatagg agtttaccaa gtaactaaaa
    25921 aacaactagc attttggatg gggtactcag aagaaagtat aagagcatta atggatagat
    25981 tcgtaaatca ccataagtgt attaaatata atcccgatac tagagaaatt gccataaaaa
    26041 actggggcaa atataactta actaaaggtg gtaaaccaat tatagattta cttaataaag
    26101 aactcaaaga agttaaagat attgagttaa taaaatatgt aattccatca atagaaaaat
    26161 cagatataag aaaaatattt gaggattatt acgaaatggc taaaaatggg gattcttacg
    26221 atacgtcgac gatacgtgaa cgagtcgtac cacgatacgg ggacaataac aataagaata
    26281 acaataagaa taacaataag aataacaaca acaataagga tgattcggtg gttgtggata
    26341 aaataaaaca atactttgat ttagaatcta aagacattga aaaaattgtt gatatattca
    26401 tacatacagg aagaggaatt gactatttag aggaaaaact aaggttggta aaaaatacag
    26461 atggagtaaa aagtattaca ggctatctca taaaagcatt agaagaagat tataagccta
    26521 taccaagtag aaaaaataag actaagtttc ataattttaa cgagacattt actaagtata
    26581 cgtctgatga actagacgag attattaaaa agagtcaaaa agagaagttc agttgaatta
    26641 aatagtctag ggagtagtta tacaatatta cttcctagga gttaaaaaat attggaggga
    26701 tagaaatgat aataattaga agtcaagata gattagattt aatgagagtt aatagagttg
    26761 aaataggttt taatcaagtg tatgcaatac ttgaaaatga tattagaaaa ataggtgaat
    26821 atgaaagtat tgaaagagct atgcaagtgt taaatgatat acagaagttt attgaaaatg
    26881 gagtaagaac agattatata gattcttgta gagttagaca taatcaagag aaagtatttg
    26941 aaatgccatt tgaataaaaa ggggggaact aaatatggct aaggtttggg tggatgcagg
    27001 aacattttta gaaagaacta aggatataga agatatgttt gaatttaatc taagaaaagt
    27061 aagagataga aataaaaaaa taaatgtaat tgatttgcgt gtaaataatg aggggcaagg
    27121 aagaaaaggt aaaaaagtag agtgttttaa tattgtgact ggagaaacta aagtatttaa
    27181 tactgctgtt gaagcaagta aatacgtata ttttacagat gtttatattg ctcatttagc
    27241 aagaacaggt aaggtttcta aaaatggatg gaaagctaga tatattcaag aggtgacaga
    27301 tggtattggc aaatgtggaa caagtaatta agttagctga aaagatatta aataagaaaa
    27361 agtgttctgt taataaagct attgatatag ttataaaaat attaagtaaa tatgagtgcg
    27421 aggggatgtt aagaaatgag tttaattaag tatagaggtt atgattttga gaacgaaaag
    27481 tggatttatt cagcaacaat aatgtggagc aatatacttg aatgtttagt tatgttgaca
    27541 gagggttgca aatggcagaa agtctctaat gttggggtat gctctggaga atgggctaga
    27601 aacaatcaag aaatttgtga gggggatata ttgaaaggat atgataattt ccatgacaca
    27661 agccaatatg gagttgtaaa aagggatatt ggtagtatta agttatattt ggaatggcat
    27721 tatttaaaga aacttgaagg agaatggata gagcttataa ataaaacaga aatatatcat
    27781 agcagagatt acaaaatagt tggtaatgaa tatgagaact tagaggaagt cagaacagag
    27841 ttcttagaac gtaaggagag tcttgagaat gaatatctta gctagtgcga tattagtaat
    27901 aggaagtttt atagctggta gagtttatga gtatagattg aatctaaaag agtgtgaaaa
    27961 ttgcgacaat aaaagaggtg tataagaatg gatgatagat tagaaatgat aaatgcttct
    28021 gtaaattata tacagatgat atgtgaaagt tcaaatatag ctattatagc agagcgagga
    28081 agagttagaa tattagattt agaaactaaa gaaaaatatg atttattaaa aaataaactc
    28141 gaggaaatgt tagaagaaat ataagtgaaa atatctaatt aagacagttt agagagttac
    28201 aaaatatctt ttagtataaa ttattgttga agtgttttgt gactctcaaa aatgaaaata
    28261 aggaggcgtt gtattgctta catttttaga tttattcgca gggataggtg gctttaggct
    28321 agggatggaa aaagcaggac ataaatgttt gggacattgc gaatatgata aattcgcaaa
    28381 tttaagttat aatgccatgc acaaaccgaa ggaggatgaa tggtttgaaa gagatattag
    28441 agaaattaga acagaaaata tcccaagagc agatgtctgg tgttttggat tcccatgtca
    28501 agacatttct gttgcaggga aacaatttgg attcagagga gaacgttcaa gtttattttt
    28561 tacagttaca aaacttatta gagaactcaa agaagaagat agacccaagt atttacttat
    28621 tgaaaacgtt aaaaatctac ttagtgttaa tggaggattt gatttcctca aagttctcgt
    28681 tgaactggat gaaatcggct atgatgcaga gtggcaagtt cttaattcta aaaacttcgg
    28741 agtaccccaa aatagagaac gaatattcat tgttggacat tttagaggac gaagtacacg
    28801 aaaagta
//
LOCUS       DAJMZY010000044        27962 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.044, whole genome shotgun sequence.
ACCESSION   DAJMZY010000044 DAJMZY010000000
VERSION     DAJMZY010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 27962)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27962)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27962
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.044"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            complement(146..2101)
                     /locus_tag="OE968_001902"
     CDS             complement(146..2101)
                     /locus_tag="OE968_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219182.1"
                     /translation="MKKYEIFIFMSIIVLCFISFPHKVFGQEENCLEDFERWVQENKN
                     NKEEIVYTLSCDMVIDEEFRFYIPYDSNFTIDTNKYKILIKNHGRFIIDDNELNIIGE
                     GGKEGVIHIENGGSISIGINNIIATDGTALYVEEGGDLHIKSSYESVEKIKANGKDAI
                     GIYTENDIRILNKDIEVNGEHAIGVYSKGDVEIEETSIKAYSSNNESGLLRDNNKLAQ
                     SIISESKKVYIIDDYNELIPSIAEDSGYDIVKCCHRGIGVFSDEIKVSKDDKIENIKF
                     PKYMVLETSSGNRLDIDVEWDFTDYYEKLEKGENFNITGKFKTEMLNKEKIIINDDVV
                     PILNVSVIEKKPIDNLELEFQNTKNGYVAVLFYDMPYSASKVFVEYSSDGINWISEEQ
                     EDIRDQAILFFEDFKLRCFRVKVVGGLKEGYSNIVFKPGFIMGGGDNQETPDDEREND
                     DIDGDRGGGGRDDPDRDEDDNNQDGNNGNENNDSNNNQNNNNENNNNENDNSDEKQPN
                     TPKDDVESSTDSNENKNPHDIPKDGNKENNSDKEKGFYNKNSITENDDNYDLSSKSVF
                     GTNEHSFPYRESISNKNQDTNKNKSNISDYDGIINNNYKLESKEYNLKKDIIFLFCIL
                     TPIMIGSILIVNPDTRKSIIKFIKLKK"
     gene            complement(2284..3759)
                     /gene="spoIVA"
                     /locus_tag="OE968_001903"
     CDS             complement(2284..3759)
                     /gene="spoIVA"
                     /locus_tag="OE968_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage IV sporulation protein A"
                     /protein_id="HCP7219183.1"
                     /translation="MNNNIYEDISKRTQGDIYIGVVGPVRTGKSTFIRKFMEKLVIPN
                     IDNEFKKDRTRDEIPQSGSGKTIMTVEPKFVPADGVEIKIKDTVSLKVRMVDCVGYIV
                     EGALGHEEGGKQRLVSTPWSQEAMTFEKAAEIGTKKVIKDHSTIGIVVLTDGSVTGID
                     RKSYVEPEERVIQELKNLKKPFAVVLNTLSPKSEETSMLRSELEEKYEVPVLPMNVVE
                     MEEEDIEEVMEAVLYDFPLTEIRINLPKWVEGLERNHWIKSSIITTLKQSIIDIGKIR
                     DIEGIIQGFSELEFLEDTGVDNVELGEGVINIDLQTKQDLFYNVLEEKSGFKIEGDYQ
                     LLSLITRLSKVKNEYDKIESALIDAKIKGYGVVAPSLEELSLEEPEIMKQGKQYGIKL
                     KANAPSLHIIKADISTEVSPIVGNQNQGEEMIKYLMEVFEEQPADLWESNMFGKSLHD
                     LVKEQLQSKLYTMPEEIRVKMQKTLQKIVNEGSSNIITILL"
     gene            complement(3931..5226)
                     /locus_tag="OE968_001904"
     CDS             complement(3931..5226)
                     /locus_tag="OE968_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCP7219184.1"
                     /translation="MSVEVNKPSIWKNFKVLIILFVAGAFIYALPYLKNYYYDTFAQA
                     FNLTNTQMGSLGSIYGLLAMVSYLFGGFLADRISARKLLSGSLIITGISGLVLTLYPP
                     YIVVFLIHALWGITTILTFWPALVKAVRMLASENEQGKAFGFMESGRGITNAIHLSLV
                     LILFGYISSKVSDKSGLTAIIVLYSAINVIVGVLVFFKLKDNEKEVSAKFDKEAFFAV
                     IKMPHTWIITIIMFCSYSANMSFYYFTPYSTEAFGATVVFASAISILAQYCRPVASAA
                     SGLLGDKVGSSKIISYGFILMIAGLLGVIFTPTKSSMIYILLIGCVAIYVSMYAIQGL
                     HYSLLEEGNYSLSISGTAIGIVATLGYLPEVLCPLAAGKILDAFPGVTGYRYYFIVLT
                     IVAIIGLVFTFIWMNMTKERRKELIEMNNNSNENTTKVS"
     gene            complement(5410..6819)
                     /locus_tag="OE968_001905"
     CDS             complement(5410..6819)
                     /locus_tag="OE968_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCP7219185.1"
                     /translation="MKKKIGFWDLVFMNISALFGIRWIAKSTASSFGLGLGSIPVWLL
                     FAFIFFVPASLICAELAATYPKDGGLGEWVKQAYGEKWGFMVSWLNWTSKIFWYSSFL
                     TFLAINIAYMLGNPDLSNNKMFILALSLIIFWLLSLVSTRGMAFGKFFTNTGALGSTI
                     PAILLIVMAFMSVVILKKAPSASIYTIQNIIPKIDANSLVSISAIIFALSGAETTANF
                     ITEMDNAKKNFPKAILTVAVLIGGIYILGSVAITMILPPDKIAASTGILDALAKVAQD
                     LGIGSWFIRIVAFGITLSVLGALILYIAGPVKMLFGNVREGVFPKQLTVTNKYNIPSN
                     AVIVQAIIVSLLLVGTNLLPSVDNIYNVLVTMTALTALFPYVLLFTSYIRLRKTRPNE
                     ERPYSIAKSDSVCINIARMVLVVTVVGILFSTAPVMETLKDNIIYEIEMIGGGLFVII
                     TGLMLWKNYEKKISNNSGR"
     gene            complement(6871..8010)
                     /locus_tag="OE968_001906"
     CDS             complement(6871..8010)
                     /locus_tag="OE968_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HCP7219186.1"
                     /translation="MSNNMRLERLRKYMNEKSIEIALIFEPDNQFYISGFKAITYSRP
                     IVTVVTQDKIELIVPGLEELHAKEVAKVDNVYVYYEIPEMKEHGISHKHYLDIILNKY
                     PKGTTVGIEKDIVSASFSEYITDKSFAIKDVGSKIFEMRYVKDAKEIEFLKIAGYLSD
                     IGIKGSLENVRVGMSELEFDVEGDNALLKYVSENYPDTYIGFANWTCSGIDRTAQPHL
                     DSNTRILQRGDIVIHSRQVWYENYRAENERTFIIGKPTERQKEVFKIAVEAQQAGLDT
                     IKAGIPARMVDEAARAVVAKYGLELYSNHRIGHGLGLSEHEEPYLRFDNELILEEGMV
                     FSMEPGIYIPGVGGFRHSDTAIVGKNGATIITNYPRSVEELILDI"
     gene            8329..8979
                     /locus_tag="OE968_001907"
     CDS             8329..8979
                     /locus_tag="OE968_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCP7219187.1"
                     /translation="MTNKELQKKRILMYFIEAAQNIMENEGIENITLRKVADMAGYNS
                     STLYKYFKNLDHLISFASIKYFKDYNLNISRCIENVNDEYKKYIIMWKLFCKHSFDNA
                     QAFYQVFFNLSSDELSYITKQYYDMFPEDLGIHDSDISLMITGESIKERNKILLNNLV
                     DTGYIPAKDLDIINDIIISFYQNLLFLKKNTGKNSDDDELTMKMISSIEYIIKHAK"
     gene            complement(9136..10155)
                     /locus_tag="OE968_001908"
     CDS             complement(9136..10155)
                     /locus_tag="OE968_001908"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HCP7219188.1"
                     /translation="MEKVCVLGTGSWGSALALGLAKKGNDVSMWTRKEEQAKKINRTK
                     ENTDYLPGVLFPNNITISTDIEKTIKDCKVIVLAVPSQAVRSTCQKIKPFIKEGQVIV
                     NVAKGLEKGTGLRLSQVCEEELPQNPYVILSGPSHAEEVARDIPTTVVVASKDLKIAQ
                     MIQDLFMSPKLRVYTNPDIVGVELGGALKNIIAFGAGICDGLGYGDNAKAALMTRGIS
                     EMSRLGIAMGANMSTFAGLSGIGDLIVTCTSMHSRNRRAGILIGKGMSLEDTLKEVKM
                     VVEGITATEVAHDVAEKLDIDMPITNAIYSVIKKGSNPKEVGIELMMRSKKHEMEEVV
                     LGDDI"
     gene            complement(10186..10800)
                     /gene="plsY"
                     /locus_tag="OE968_001909"
     CDS             complement(10186..10800)
                     /gene="plsY"
                     /locus_tag="OE968_001909"
                     /EC_number="2.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HCP7219189.1"
                     /translation="MEIFSYIIIAVVAYLLGNISTSYIVAKRIAGVDIRTQGSGNAGS
                     TNVLRTLGKRAGAMTFLGDVLKGVMAVLISEFAARLVGIDTLLAGYLAVICVVAGHNW
                     PAVLGFRGGKGVATSLGAMLAVNPVITLMCLAVFILVVAITKYVSLGSVVGIGCSPIF
                     MIMVKNKAGLIVALFLTASVIYNHRANIKRLLNGTERKIGQKKE"
     gene            complement(10835..12154)
                     /gene="der"
                     /locus_tag="OE968_001910"
     CDS             complement(10835..12154)
                     /gene="der"
                     /locus_tag="OE968_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012063975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HCP7219190.1"
                     /translation="MSRPVVAVVGRPNVGKSTIFNKFAGKRISIVENTPGVTRDRIFA
                     EVEWLDKYFTLVDTGGIEPDSEDIILSQMRNQAMLAMDMSHVILFIVDGKAGITAADK
                     EIAQLLRKTKKPVILVVNKIDSQSQFDNIYDFYELGFGTPFAVSGANSMGFGDLLDEI
                     VENFPAGLDTEYEEDIIRVAITGKPNAGKSSILNKILGEERVIVSPIAGTTRDAIDTY
                     FEKNGQKFLLIDTAGLRRKSKIYETIEKYSVIRAMSAVDRADVVLIVIDALEGVTEQD
                     TKVAGIAHDEGKGCIFVINKWDLIEKDNKTMSNYTKDIKEKFPFMMYAPIVFVSAKTN
                     QRMNKILDTVEYVSNEHSKRISTSALNEVIGEAVMLNQPPSDKGRRLKIYYGTQTDIR
                     PPKITLFINDKDLTHFSYQRYLENKIRENFGFEGTSIKFEYRQKNKK"
     gene            complement(12188..13516)
                     /locus_tag="OE968_001911"
     CDS             complement(12188..13516)
                     /locus_tag="OE968_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF512 domain-containing protein"
                     /protein_id="HCP7219191.1"
                     /translation="MEVNVKKVNNIISKVYKDSIAEEIGIEVGDLLISVNEQPIHDII
                     EYRFLLSDEYLDVEIQKKDGEVYIYEIEKDYDEDLGVEFTNPIIDQAKSCRNKCMFCF
                     IDQLPEGMRETLYFKDDDSRLSFLQGNFVTLTNMSEEDINNIIKYRISPINISVHTTN
                     PELRQKMISNKFAGKLYGIMKRLADTHIEMNCQIVLCPGINDGKELDRTIKELAQLYP
                     YVNSVAIVPVGITKHRENLVELNIFNDKSASKTIEQIHQIQQKYLEKLGTRFAFLSDE
                     FYILSNSELPGYEEYEGFLQFEDGVGMIRKLKTEIEEYLNILPEKILKREKKVSIATG
                     HSAYEFIQSMADAMMDKFKNLQVNVYEIKNKFFGETITVSGLLTAKDLKEQLEDKELG
                     EALYITRSMLKADEEIFLDNIELNQLEELMRIKIIPCLNEGKDFVDKILK"
     gene            complement(13754..13954)
                     /locus_tag="OE968_001912"
     CDS             complement(13754..13954)
                     /locus_tag="OE968_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219192.1"
                     /translation="MGMDIGLNEYTLAIVTLDKNMKNGGGCPIFYANDEKDLQNKALL
                     MSKCVGGMVHDMTNGTLIIVKH"
     gene            complement(13956..14888)
                     /locus_tag="OE968_001913"
     CDS             complement(13956..14888)
                     /locus_tag="OE968_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YIEGIA family protein"
                     /protein_id="HCP7219193.1"
                     /translation="MDRVFFVAVIIGITSRIIMLNLDQKQYPTQPNVLLSQLILAFVA
                     SSLGALLVPALINRSYTSITFLSLAAEQFRQVRANRRNTLQNLEEVQLVKRGAAFIEE
                     IARTYEVRNYMCIVTSFLTIGLYYVILAETKISEGMSLVISSICGLVLAFILKKLLTR
                     KSIGDIADVMPAEISFVDESILKVGDLKGITNIGLKSDREVYINRGVGIQIIPKNKDY
                     ANAGILFDSGQRQAIVYNIYSRLGLYGDYGEPSFVPLPRRNKEDESIMIAYLPVDKNV
                     EKVMEAVKSCPILSSSKGKNLSLKNYKIGKKGSA"
     gene            complement(14933..15865)
                     /locus_tag="OE968_001914"
     CDS             complement(14933..15865)
                     /locus_tag="OE968_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YIEGIA family protein"
                     /protein_id="HCP7219194.1"
                     /translation="MEESLLNANLFRHSFIVALVVGILCRGLVLRVTDKQYPSRPQDY
                     LEQIIISGLSASLGAIALPALIDKEFAALTFFAVAIQQFQGLAEQERITLKNIDNEEL
                     VPKGDAYVEEIASTYESRSYISLFSALVSSIVYIVFARKYGLSFFYCTILAIVSGAIV
                     GLIFRRFLRRNSIADIADIVPAKISFEGPILMVNGVIITNIGLESTREKYRNECLAIE
                     VIPRDLGAFGIVNDIGQRQAIIHNLFIHMGIDRDVDEVDIVAISKTNLEKSTVVIPYM
                     PILKDIDVMIDVVKSTPIIETSKGKQSDFSRKTL"
     gene            complement(15920..17209)
                     /locus_tag="OE968_001915"
     CDS             complement(15920..17209)
                     /locus_tag="OE968_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HCP7219195.1"
                     /translation="MEDLNSIYFFIVMLSIAIVILAVRYTITLRKYLKEFIYVSKKVS
                     NNEYHARLNISAKGELGELARNFNHMIKNMDKTLEEVQYKHLQLRSILKSISHGILAI
                     DVNGNILLINDEAKEMIKSEPNQLVEGHNINVVIKEEEILKQILQFIGSKDNETANIT
                     TKDDIVYKIKVDPVYLQNTNNVIIGSIVNIEDITKKVKLENMRSDFVANVSHELKTPL
                     TSISGFVETLKSNENIDVNTRNRFLEIIESESDRLKRLIDDILLLSFVENKDTLLMEN
                     VVVYDVFKEVYEITQHSASEKNIEVLYKCDDKSISILSNKDYIKQVFLNLVDNAIKYT
                     QDNGIVQVVVLKDEEKIVIKVIDNGVGIPKEDVERIFERFYRVDKARSRDVGGTGLGL
                     AITKHIVKSLNGCIKVKSELGIGSEFIVTILQKNFLK"
     gene            complement(17238..17930)
                     /locus_tag="OE968_001916"
     CDS             complement(17238..17930)
                     /locus_tag="OE968_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCP7219196.1"
                     /translation="MNTKVLVIDDEMHIVELLKFNLEVSNYEVSYSYDGFDGFIKAKE
                     IKPDLILLDWMLPNISGIEVLRKIRSDKDLKNIPVIMLTAKNMENDKVEGLEIGADDY
                     ITKPFSIKELLARISSVLRRYNLTSLGEENNILTTGNLKLDLSKHEVTKGSEKIELTL
                     KEFELLKLLIQNKGKVLSRNYLLDKIWGYEYYGETRTVDVHIRYLRKKIEDEDKSEKY
                     IETIRGVGYKID"
     gene            complement(17945..18706)
                     /gene="pgeF"
                     /locus_tag="OE968_001917"
     CDS             complement(17945..18706)
                     /gene="pgeF"
                     /locus_tag="OE968_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan editing factor PgeF"
                     /protein_id="HCP7219197.1"
                     /translation="MMKDYINIKNVQDIKEYVNLSGNCEELDEKLNSVNLVITCKNID
                     AKNREDMLKVCKECDLTFENLTSNSQIHSDIVNIVNKDTIGKRRDGDALITNLEKVPL
                     LLFTADCVPISIIDAKNKAIGLAHAGWRGTFSNIGHKTIKLMSECYKTVPEDLVCIIG
                     PSIGPCCYEVSEDLVEKFNTILTNNDEKFYIIKEGSYYLDLWKINEYMLRCSGVKKEN
                     IINLNLCTSCRADKFHSYRKHNKASERIGTVLQIK"
     gene            complement(18703..19164)
                     /gene="nrdR"
                     /locus_tag="OE968_001918"
     CDS             complement(18703..19164)
                     /gene="nrdR"
                     /locus_tag="OE968_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HCP7219198.1"
                     /translation="MQCPYCNYKESKVIDSRHTDLKSIRRRRECESCKKRFTTYEKIE
                     TTPLMVIKKDNSREYFDREKIKYGLLKACEKRPVSIDEIESIVVHIENEINKCFIEEI
                     ETKKIGEMVMDKLKELDEVAYVRFASVYRQFKDINTFVNELKSILIEKGDK"
     gene            complement(19186..19449)
                     /locus_tag="OE968_001919"
     CDS             complement(19186..19449)
                     /locus_tag="OE968_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlmC/YmxH family sporulation protein"
                     /protein_id="HCP7219199.1"
                     /translation="MIRVSDIMEKEIINVKNGKRMGFIIDIDMDIHEGKVVSFTIFGD
                     GSRSFFSRGGDEEVIFWNDILKIGCDTIIVNIGSELSLDEFEI"
     gene            complement(19553..20326)
                     /gene="sigG"
                     /locus_tag="OE968_001920"
     CDS             complement(19553..20326)
                     /gene="sigG"
                     /locus_tag="OE968_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011986856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigG"
                     /protein_id="HCP7219200.1"
                     /translation="MQVNKVEICGVNTSELPVLKNKQMKELLLQIKNGDEEARQQFVR
                     GNLRLVLSVIKKFNNRGENIDDLFQIGCIGLIKAIDNFDLSQNVRFSTYAVPMIIGEI
                     RRYLRDNNPIRVSRSLKDIAYKALQVRERLIRTNSKEPTVSEIAKELELEVESVVMAL
                     DAIQDPISLFDPVYQDNGDAIFVMDQVQDKKDTDENWLQEISLKEAIKKLNSREKLVL
                     DLRFYKGRTQIEVADEIGISQAQVSRIEKNALKNMRKYV"
     gene            complement(20418..21140)
                     /gene="sigE"
                     /locus_tag="OE968_001921"
     CDS             complement(20418..21140)
                     /gene="sigE"
                     /locus_tag="OE968_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigE"
                     /protein_id="HCP7219201.1"
                     /translation="MLRLKERIISFITMLGIKLKIIKPKGIYYMGGANILPPPLKPEE
                     EMELLQKLETDESVKSILIERNLRLVVYISRKFENTGIDVEDLISIGTIGLIKAVNTF
                     KLNKNIKLATYASRCIENEILMYLRKNNKKKTEVSFDEPLNIDLDGNELLLSDVLGTE
                     NDEIYKIIEEEIDRDLLVMALDRLSDREKQIMELRFGLIDKGIEKTQKEVAGMLGISQ
                     SYISRLEKKIISRLQKEMKKFV"
     gene            complement(21165..22037)
                     /locus_tag="OE968_001922"
     CDS             complement(21165..22037)
                     /locus_tag="OE968_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-E processing peptidase SpoIIGA"
                     /protein_id="HCP7219202.1"
                     /translation="MFKGFKGGYMVYIEYYVIENLVINYIIISCTSILTKRYNPKKNK
                     LLGASLGGAYSVAYLYPSMNILFTVPFKIIIMSIITLISFRSKSKKDYVHVALVFYLV
                     NIFISGSTYFIIYFTGISHLKISFLIACTYVSCELLKYIYKDLKMLKYIKELTKTINI
                     NLLEKSFCCKALVDSGNLLKDPISQSDVIIVKSSVLEGFIPEKLLNINYEDIDMKKAQ
                     EIIGSLDDKTSGRVRIIPYKHAGSNKTSIIIGLKADYIEVDEQKIGNIILGISNFNDR
                     EYGAIMNPNILPGF"
     gene            complement(22327..23601)
                     /locus_tag="OE968_001923"
     CDS             complement(22327..23601)
                     /locus_tag="OE968_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HCP7219203.1"
                     /translation="MIKLKKVLSLVMVGILSVSILAGCSKKEDSKGKEGKEKLVVWSA
                     PLTDHDADAWKPIFEKFEKENNCEIEFQIVPWDNYAEKYATAISAGEGPDIGYMYAEM
                     FPQFIEMGAVEDLTPYLEKSGTSDNYLYLDDAKMMGGIYGLPIEAANPGVLYYNKDIL
                     EKLGEKPPKTWDDFKRICEKATKDTDGDGKIDQWGLAQGWGSKVFGSLNWNWYPYLWQ
                     AGGDIYNDDLKSVKFNNAEGLKAANFINDMKKYIPEDALSKDSNEMIESVFGPGKAAF
                     TIMLSSAATSTFDKSFPDLNWGYVTSLEDKTVGSFASVDDLTLMSACKNKELGFKLLE
                     YMLSKESMEAFHKEIPRAPVAKGEKYQGDPRFEEMVTRDKHMYRPLTVGPHGVEIYEY
                     LWKQLQMMIAGDITPEQALNESAKYANGLLAQ"
     gene            complement(23885..25042)
                     /gene="ftsZ"
                     /locus_tag="OE968_001924"
     CDS             complement(23885..25042)
                     /gene="ftsZ"
                     /locus_tag="OE968_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HCP7219204.1"
                     /translation="MLNFDVELEECAQIKVIGVGGGGNNAVNRMVEAQLKGVEFISVN
                     TDKQALYTSKAEYKVQIGEKLTRGLGAGANPEVGKRAAEESKDEIVKLLQGADMVFVT
                     AGMGGGTGTGAAPVVAGLAKEMGILTVGVVTKPFAFEGKIRMKNAEGGIAELKSKVDT
                     LITIPNDRLLQIVQKNTSMLDAFAVADDVLKQGIQSISDLIAVEGLINLDFADVTTIM
                     KDKGLAHMGIGSASGETRAIDAARQAIQSPLLETSIQGAKGVLLNVTGGPNLGLFEVN
                     EASTLVMESCDPEANVIFGASIKEDLGDEIMITVIATGFEGLQNGALDLDTKPKSSIR
                     SSLNTTVKQAVKEIEEEVIAEEKIEPPKKASIIEEDDDESMEIPTFLRRRR"
     gene            complement(25232..25585)
                     /locus_tag="OE968_001925"
     CDS             complement(25232..25585)
                     /locus_tag="OE968_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small basic family protein"
                     /protein_id="HCP7219205.1"
                     /translation="MLWVLGGLAFGVVVGYYIPFTYSMDYSIYMSVAILAIMDSIFGA
                     IKSNFEDNYDNVIFITGFIGNAILAILLTYIGEKLGVSLYYVAVLVFGMRLFNNLSII
                     RRYIISNIMNKKRKN"
     gene            complement(25684..26358)
                     /locus_tag="OE968_001926"
     CDS             complement(25684..26358)
                     /locus_tag="OE968_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF881 domain-containing protein"
                     /protein_id="HCP7219206.1"
                     /translation="MKKKIVILGAFILGVFISTYIKSLDPNRVYITLGQTESIESEVE
                     NTKKEIKNLKETLKKNKKTLNEYKEAKKNGNESIQTLMQKELEEVKELSGYSTVTGPG
                     ITITMRDSERELKDGQNPNDLIIHDIDILRVLNDLKKAGARAISINGERVLATSKIKC
                     SGATITVNDTTYGQPFIIKAIGDIDLLSAAINSPESYAKSLKDIYGINIKVQENNGNK
                     VNLFAK"
     gene            complement(26363..27061)
                     /locus_tag="OE968_001927"
     CDS             complement(26363..27061)
                     /locus_tag="OE968_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF881 domain-containing protein"
                     /protein_id="HCP7219207.1"
                     /translation="MKKRFINKSIIIGSIVLGVLVSLQLKIINIENRGMTTFKRGEQL
                     TEELKSLKKEKENLQSEVNSVKKDIEIYRGKNNEGEQDILKSEIEKYETLAGYTDVEG
                     TGIKIEINSTKDLGNSDKNDSILYNYDLLLSMINKLNSAQASAISINDQRIVSNTYMY
                     LKEDKLYMNDTVIKEPIIIKAIGDSDTLASALNIKYGIVWEIETYYNAKVKVTKEDNI
                     EINGHSDINKAEGK"
     gene            complement(27084..27824)
                     /locus_tag="OE968_001928"
     CDS             complement(27084..27824)
                     /locus_tag="OE968_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsQ-type POTRA domain-containing protein"
                     /protein_id="HCP7219208.1"
                     /translation="MKKRRKLNTNNVMIVLVFILMLSFCICIIVKSDLFDVKKIDVIG
                     NKRVTKSNIMKELNVNLNENIFAYNFKDMKNKLIKNPYIENVEIKRKLPNKIIISLKE
                     KEIFAVLKDEDNYCYIDKKGNLLEELRGSNESKKDLIVDVDYSIDDNKSIKFKNYKTK
                     ENVFKTLNYLKEEGIYRKINYVNLKKESNIEMLTRSNIKILLSNDDNLDYNISRVSKI
                     LIDLQNKNTNGGTINLNYGKLAVYSPEG"
BASE COUNT         8670 a         5135 c         2876 g        11281 t
ORIGIN      
        1 ttttttttca atattctatt atttttatac tatttagaaa attcatatat tatatatgtt
       61 ttctcaacaa caaatacagt tttcataata atgaaaggta ttacttagca atctcatgat
      121 tttctaaata atacctttct aaaaattatt tttttaattt tatgaattta attatacttt
      181 ttctagtatc aggatttaca attaatatag aaccaatcat aattggtgtt agtatacaaa
      241 ataaaaaaat aatatctttt tttagattat attctttaga ttctaattta taattattat
      301 ttattattcc atcataatca cttatatttg acttattttt atttgtatct tgatttttgt
      361 tagaaatact ttccctataa ggaaaagaat gttcattggt accaaatact gattttgagc
      421 ttaaatcata attatcatca ttttctgtaa ttgaattttt attgtaaaat cctttttctt
      481 tatcagaatt attttcttta ttaccgtctt taggtatatc atgaggattt ttattttcat
      541 tgctatcagt acttgattct acatcatctt taggagtatt tggttgtttc tcatcagaat
      601 tatcattttc attattatta ttttcattat tattgttttg attgttatta ctatcattat
      661 tttcatttcc attattccca tcttgattgt tatcatcctc atctctatcc gggtcgtctc
      721 tacctcctcc tccacggtca ccatcaatat catcattttc ccgttcatca tctggcgtct
      781 cttgattgtc tccgcctccc attataaatc ctggtttaaa aactatattt gaataccctt
      841 cttttaatcc tcctaccact tttactctaa aacaacgcaa cttaaaatct tcaaaaaaaa
      901 gtatagcttg atctctaata tcctcctgtt cttcagatat ccaattgatt ccatcgcttg
      961 aatattcaac aaaaacctta cttgcactat acggcatatc ataaaataaa acagctacat
     1021 atccattttt tgtattttga aattccagtt ccaaattgtc tattggtttt ttctctataa
     1081 cagatacatt caaaatagga actacatcat catttattat aattttttct ttatttaaca
     1141 tttctgtttt aaactttcct gttatattaa aattttctcc cttttccaac ttttcataat
     1201 aatcagtaaa atcccattct acatctatat caagtcgatt accactagat gtttctaata
     1261 ccatatattt gggaaatttt atattttcta ttttatcatc tttacttact tttatttcat
     1321 cactaaatac accaattccc ctatgacaac atttcacaat atcatagcca gaatcttcag
     1381 ctatagaagg tataagctca ttataatcat caattatata aactttctta ctttctgata
     1441 taattgattg tgccaactta ttattatctc ttagtaaccc actttcattg ttgctactat
     1501 atgcttttat tgaagtttct tctatctcaa catcaccttt agaataaaca cctatagcat
     1561 gttctccatt cacttcaata tccttattta gtattctaat atcattttca gtataaattc
     1621 ctattgcatc ttttccattt gcctttattt tttcaacaga ttcgtaggat gatttaatat
     1681 gtaagtctcc tccttcttca acgtataagg ctgtcccatc agtagcaatt atgttgttta
     1741 taccaatact tatacttcca ccattttcta tatgtattac tccttctttt cctccttcac
     1801 ctattatatt caattcatta tcatcaataa taaatctccc atgatttttt atcaatattt
     1861 tatatttgtt ggtatctatt gtaaaattac tgtcataagg aatataaaat ctaaactctt
     1921 catctattac catatcacaa gaaagagtat aaactatttc ttctttatta tttttatttt
     1981 cttgaaccca cctttcaaaa tcttcaagac aattttcctc ttgtccaaaa actttatgtg
     2041 gaaaacttat aaaacacaaa actattatac tcataaaaat aaatatctca tactttttca
     2101 tcttacactc ctagaaattt ttagctttga aacaatcctg tcgaaacata tacttcaccc
     2161 actataattt ttccacaatt atcaattatt gtcaatttat ataagtatct ttattaattg
     2221 ttataaataa aaagctactt actaaagcaa acagacgttt cactttaata agtagctata
     2281 tttttataac aaaatagtta taatattaga acttccttca tttacaattt tttgtaaagt
     2341 cttttgcatt ttaactctta tctcttctgg catagtatat aatttacttt gtaattgctc
     2401 ttttactaag tcatgtagtg atttaccaaa catatttgat tcccataaat ctgctggttg
     2461 ctcttcaaat acttccataa gatattttat catctcttca ccttgatttt gatttccaac
     2521 tattggagaa acctctgtag atatatctgc ttttataata tgaagtgatg gtgcattggc
     2581 ttttaacttg ataccatatt gttttccttg tttcattatt tctggttctt ccagactaag
     2641 ttcttctaag gaaggagcta ctactccata tccttttatc ttggcatcta ttaaagcact
     2701 ttctatttta tcatactcat ttttaacttt agatagtcta gttatcagac taagcagttg
     2761 ataatctcct tcaattttaa atccactttt ttcttcaagg acattataga ataaatcttg
     2821 ctttgtctgt aaatcaatat ttataacacc ttctcctagc tctacattat caacacctgt
     2881 atcttccaaa aactctaact cagaaaatcc ttgtataata ccttctatat cccttatttt
     2941 acctatatct ataatacttt gttttaatgt tgttattatg ctacttttta tccaatgatt
     3001 tctttcaaga ccttcaaccc attttggtaa gttgattctt atttctgtaa gtggaaaatc
     3061 atataataca gcttccataa cctcctctat atcttcttct tccatttcaa ccacattcat
     3121 tggaagaact ggaacttcat acttttcttc caattcactt ctaagcatac tcgtttcctc
     3181 actttttgga cttaacgtat ttaaaaccac tgcaaatggt tttttaagat ttttcaattc
     3241 ttgtataact ctctcttctg gttctacata gctttttctg tcaattccag taactgaacc
     3301 atctgtcaag acaactatcc ctattgtaga atggtctttt ataacttttt tagttcctat
     3361 ctctgctgcc ttttcaaatg tcatagcttc ttgtgaccaa ggagtggata ctaatctttg
     3421 ttttccacct tcctcatgcc ctaaagctcc ttcaactatg tatccaacac aatctaccat
     3481 tcttactttt aaagatactg tgtcttttat ttttatttct acaccatctg ctggtacaaa
     3541 ttttggttcc actgtcatta tcgttttacc tgaaccactt tggggtatct catctcttgt
     3601 tctatccttt ttaaattcat tgtctatatt aggtataacc aacttttcca taaattttct
     3661 tataaaagtt gattttcctg ttcttacagg tccaactact ccaatatata tatccccctg
     3721 agtccttttg gatatatctt cgtatatgtt attattcata ttattcctcc tatacatcta
     3781 atcttattaa attatattta gagttaaggg ttaatattct taaaatagaa aaataaagac
     3841 cagcaatatt aatttaattt acatatagaa atttgtaaat ttcaatgtaa attaaattaa
     3901 tattgctggt ccaaatagta gtgtattata ttaactgact ttagtagtat tttcatttga
     3961 attattattc atctcaataa gttctttacg tctttctttt gtcatgttca tccatataaa
     4021 tgtaaacacc aatccaatta tggctactat agtaagaact atgaagtagt acctatatcc
     4081 agttacaccc ggaaatgcat ccaatatctt ccctgctgct aaaggacaaa gtacttctgg
     4141 aagatatcct aatgtagcaa ctattcctat agcagttcct gatattgata atgaataatt
     4201 accttcttca agtaacgaat agtgtaaacc ttgaattgca tacatagata catatattgc
     4261 aacacatcca atcaatagta tataaatcat agatgatttt gttggtgtaa atattacacc
     4321 taaaagacct gcaatcataa gtataaatcc ataagatata atctttgatg aaccaacttt
     4381 atctccaagt aatccagaag cagctgatgc tactggtcta caatactgag ctaatattga
     4441 gattgcagat gcaaacacca cagtagctcc aaatgcttca gttgaataag gcgtaaaata
     4501 ataaaatgac atattagctg aatatgaaca aaacattatt attgttatta tccatgtatg
     4561 aggcattttt attactgcaa aaaaggcttc tttatcaaat tttgctgata cctctttttc
     4621 attatccttt aatttgaaaa atactaatac tccaactatt acatttattg ccgagtataa
     4681 tactataata gctgtaagac cagatttatc acttactttt gatgaaatat acccaaatag
     4741 tatcaatact agagatagat gaattgcatt ggtaattcca cgaccacttt ccataaatcc
     4801 aaaagctttt ccttgttcat tttcagatgc taacattcta acagctttta caagagctgg
     4861 ccaaaaagta agtattgttg ttattcccca taaggcatgg attaaaaaca caacaatata
     4921 tggaggataa agtgttaata caagaccaga tattcctgta ataattaaag aacctgaaag
     4981 caattttctg gctgaaatac ggtctgctaa aaaaccacca aaaaggtatg ataccattgc
     5041 aagtagacca taaatacttc ctaagcttcc catttgtgta tttgtaagat taaatgcttg
     5101 tgcaaaagta tcataataat aattctttaa atatggtaaa gcatatataa atgctcctgc
     5161 tacaaagagt attatcaaga ctttgaaatt tttccaaatg cttggtttat ttacttcaac
     5221 tgacatactt cctccttatg taaatacctg taaattttca tgataattaa ttattgctta
     5281 ttgtattgtt tattcaatat ttcggaatat ttattaatat attaggttaa tctatcaata
     5341 atttatggtg agttatgagc taaaagtaaa ctcttttagc tcaccataat aattatattt
     5401 ttatttatac taacgtccag agttattaga tatctttttt tcatagttct tccatagcat
     5461 taaacctgtt attataacaa aaagacctcc tcctatcatt tcaatctcat agattatatt
     5521 atcttttaaa gtctccataa ctggtgccgt tgagaaaagt atgccaacta cagttactac
     5581 aagtaccatt ctggcaatat tgatacaaac tgaatcactt tttgcaattg aatatggtct
     5641 ttcttcattt ggtcttgtct ttctaagtct aatataagat gtaaaaagca agacatatgg
     5701 aaataatgct gttaatgctg tcatagtaac aagaacattg tatatattat ctactgatgg
     5761 taataagttt gttcctacaa gaagtagact cactattata gcctgaacta ttactgcatt
     5821 tgatggtata ttgtatttat ttgtaacagt caattgctta ggaaatacac cttctcttac
     5881 atttccaaaa agcatcttta ctggacctgc tatataaagt attaatgctc ctagtactga
     5941 taaagttatt ccaaatgcta ctattcttat aaaccaactt cctataccta aatcttgtgc
     6001 aactttagct aatgcatcta gtatccctgt agatgctgca attttatctg gaggaagtat
     6061 cattgttatt gctactgaac ctaagatata gattcctcct attaaaacag ccacagttaa
     6121 tatagcttta ggaaagtttt tcttagcatt atccatttcg gttatgaaat tagcagtcgt
     6181 ttcagctcct gataatgcaa atattatagc agatatagaa actaatgaat tggcatctat
     6241 ttttggtatt atattttgga ttgtatatat cgatgctgat ggagcttttt tgagaataac
     6301 tacagacata aatgccatca ctataagtaa tatagcagga attgtagaac ctaatgctcc
     6361 tgtattcgta aaaaattttc caaatgccat cccacgagta cttactaagg acaacagcca
     6421 aaatattatg agtgaaagtg ctaaaataaa catcttattg tttgataaat ctggatttcc
     6481 aagcatatat gcaatattta tagctaaaaa tgtcaagaaa gaagaatacc aaaatatctt
     6541 tgatgtccaa tttagccatg acaccataaa tccccacttc tctccataag cttgtttaac
     6601 ccattctcca agtccaccat cttttggata tgttgcagcc aactctgcac atataagtga
     6661 tgcaggaaca aagaatataa aagcaaacaa taaccaaact ggtatagaac caagacccaa
     6721 tccaaaacta gaggcagtag atttagctat ccatctaatc ccaaatagtg ctgatatatt
     6781 cataaatact aaatcccaaa atccaatttt ctttttcact gtaattcctc caatttcaaa
     6841 tttattcaaa ctcatacact atgtattgat ttaaatatca agtataagtt cttcaacact
     6901 tcttggataa ttagttataa ttgtagcacc attcttacct actattgctg tatctgagtg
     6961 tctaaatcct ccaactccag gtatatatat ccctggttcc atagaaaata ccattccttc
     7021 ttctaatatt aattcattgt caaatcttaa atatggctct tcatgttctg acaaacctaa
     7081 accatgacca attctatgat ttgaatataa ctctagacca tactttgcaa caacagctct
     7141 tgctgcttca tccaccattc ttgctggtat accagctttt attgtatcta atccagcttg
     7201 ttgagcctct actgcaatct taaacacttc tttttgtctt tctgttggtt tgcctataat
     7261 aaaagttctt tcattttctg ctctatagtt ttcataccaa acctgtctac tatgtattac
     7321 tatatctcct ctttgaagta ttctagtatt agaatctaaa tgaggttgtg ctgttctatc
     7381 aatccctgaa caagtccagt ttgcaaatcc tatatatgta tcaggataat tttcagaaac
     7441 atattttagt aaagcattat ccccttcaac gtcaaactcc aattcactca tcccaactct
     7501 aacattttct aaagaccctt ttattcctat atcagatagg taacctgcta tcttcaaaaa
     7561 ttctatttct tttgcatctt ttacatatct catttcaaat attttacttc caacatcttt
     7621 gatagcaaat gacttatcag ttatatactc tgaaaagctt gcagatacta tatctttttc
     7681 tattccaaca gttgttcctt tagggtattt atttaaaatt atatctaagt aatgtttatg
     7741 tgatattcca tgttctttca tttctggtat ttcataatac acatatacat tatcaacttt
     7801 tgcaacttct ttagcatgta attcttctaa tccaggtact attaattcta ttttatcttg
     7861 agttactact gttacaattg gtctagaata agttattgct ttaaatccac taatataaaa
     7921 ttgattgtct ggttcaaata ttaaagcaat ttcaatgctt ttttcattca tgtactttct
     7981 caatctttct agtctcatat tatttgacat aatgcacctc tttcttaata ttcagataat
     8041 ttattcaata caacaaggat gaatatatta ttttaaaatt cttaatattt ttagtacttg
     8101 tcgtatttgt atgtaaatta attttatttg tgattatttt atcataatca tgattatttt
     8161 gtcaatcatg attttatttt aaaaaatttt ttatattcta gtgattttaa attatctaaa
     8221 atataacgag tatacattgt attttgtaat attattcttg atttatggta agtttaatga
     8281 taaaatcacg attatataaa ctatattgat tatttgtagg tgaataaaat gacaaataaa
     8341 gaattacaaa agaaaaggat attgatgtat ttcatagaag ctgctcaaaa tattatggaa
     8401 aacgaaggta tagaaaatat tacacttcgt aaggttgcag atatggctgg ctataatagt
     8461 tcaactctat ataaatactt taaaaattta gaccatttaa tatcatttgc atctataaaa
     8521 tattttaaag attataactt gaatatttca agatgtatag aaaatgtcaa tgatgaatat
     8581 aagaaatata taattatgtg gaaattattt tgtaagcatt cttttgataa tgctcaagct
     8641 ttttaccagg tattttttaa cttgtctagt gatgaactta gctatataac aaaacaatat
     8701 tatgatatgt ttccagaaga tttaggtatt catgatagtg acatatcttt aatgattaca
     8761 ggagaaagta taaaggaaag aaataagata ctattaaaca atcttgtaga tactggatat
     8821 ataccagcta aagatttaga cataatcaat gatataatta tttcttttta tcaaaatcta
     8881 ttattcttaa aaaagaacac aggaaaaaat tctgatgatg atgaattaac tatgaaaatg
     8941 atttcttcta ttgaatacat aataaaacat gctaaataaa attaaaatat ggctgtctca
     9001 aaatagagat aagccttttt tattgttgaa ataataaaaa tatatttaat ttcatataaa
     9061 aatgagtgcc tcgtaaacta aaaagttcat tttgagacac ccctaaaata aatttattat
     9121 ttattataca atagtttata tatcatcacc taaaactact tcttccattt catgcttttt
     9181 acttctcatc attagttcta ttccaacttc tttaggattt gaacctttct ttattacaga
     9241 atatatagca ttagttatag gcatatctat atctaatttt tcagcaacat catgtgctac
     9301 ttcagtagca gttatgcctt ctacaaccat ctttacttct tttaaagtat cttctaaact
     9361 catcccttta cctatgagta taccagctct tctatttcta ctatgcatac ttgtacaagt
     9421 aactattaaa tctccaatac ctgaaagacc tgcaaaggta gacatattag ctcccatagc
     9481 aattccaagt ctgctcattt cactaatacc tcttgtcata agggcagctt ttgcattatc
     9541 accataccct aatccgtcac atatcccagc tccaaatgct ataatatttt ttaatgctcc
     9601 tccaagttct actccaacta tgtctggatt cgtataaact ctaagtttag ggctcataaa
     9661 caaatcttgt atcatctgtg ctatttttaa atctttagaa gcaactacta cggtagtagg
     9721 aatatccctt gctacttctt cagcatgaga tggcccagat agtattacat atggattttg
     9781 tggtaattct tcttcacaga cttgtgataa tctaagccca gtcccttttt caagaccttt
     9841 agctacatta acaataactt gtccttcttt tataaatggt tttatttttt ggcaagtact
     9901 tcttacagcc tgtgatggaa ctgctaaaac tattacctta caatctttta tagttttttc
     9961 tatatcagta cttatagtta tattatttgg aaataatact cctggtaaat agtctgtatt
    10021 ttctttagtt ctgtttattt ttttagcttg ttcctctttt cgagtccaca tgctcacatc
    10081 attacctttt tttgcaagcc ctaaagctaa tgcacttccc cagcttccag tacctaatac
    10141 acatactttc tccatgttta acaccacctg agtataatat atttactatt ctttcttttg
    10201 accaattttt ctctctgtcc catttaataa tcgctttata tttgctctgt gattatatat
    10261 tactgatgca gttaagaaca gagctactat taaaccagct ttatttttta ccataatcat
    10321 aaatattggt gaacatccta ttcctacaac agaacccaat gaaacatact ttgttatagc
    10381 taccaccaat ataaatactg ctagacacat tagtgttatt actggattta cagctagcat
    10441 tgcccctagt gaagttgcaa cacctttgcc tcctctaaat cctaaaaccg ctggccaatt
    10501 atgacctgct acaacacata taactgccag atatccagct aaaagagtat ctattccaac
    10561 caatcttgct gcaaattctg atattaaaac agccattaca cctttaagaa catcacctaa
    10621 aaatgtcatt gctcctgctc tttttccaag tgtcctaagt acatttgtcg aacctgcatt
    10681 accagaacct tgagtcctta tatcaacccc agcaattcgc tttgcaacta tgtatgaggt
    10741 agatatattt cctaaaagat atgcaactac agcaataatt atataactaa atatctccac
    10801 tgaatttccc ccctttagtt atattttaag atatttattt tttatttttt tgtctatact
    10861 caaactttat ggaagttcct tcaaatccaa aattttctct tatcttattc tcaaggtatc
    10921 tttgatatga gaagtgagtt aaatccttat catttataaa caatgtaatt ttaggaggtc
    10981 taatgtcagt ttgagtccca tagtaaattt ttaatcttct acctttgtca gatggtggtt
    11041 gatttaacat tacagcttct ccaattactt cattcagtgc tgaagttgat attctcttag
    11101 aatgttcatt tgacacatat tcaactgtat ctagtatctt gttcattctt tgattagttt
    11161 ttgcagaaac aaatacgatt ggagcataca tcataaatgg aaatttttct tttatatctt
    11221 ttgtgtaatt actcatagtc ttattatctt tctctattaa atcccattta ttgattacaa
    11281 atatgcatcc ttttccttca tcatgtgcta tacctgcaac ctttgtatct tgttctgtta
    11341 caccttctaa ggcatctatt actatcaata ctacatctgc tctatctaca gcactcatag
    11401 ctcttattac actgtatttt tctattgtct catatatttt actttttctt ctaagccctg
    11461 ctgtatctat tagaagaaat ttctgtccat ttttttcaaa ataagtatca attgcgtctc
    11521 tagtagttcc tgcaattgga cttacaatta ctctttcttc tccaagtatc ttattgagta
    11581 tagaactttt tcctgcattt ggtttacctg ttatagctac tcttattata tcttcttcat
    11641 actctgtatc taatcctgct ggaaaatttt caactatctc atctaataaa tctccaaatc
    11701 ccatactatt ggctcctgaa actgcaaaag gcgttccaaa tcccaactca taaaaatcgt
    11761 atatattatc aaattgactt tgactatcaa tcttattaac cactaagatt actggttttt
    11821 ttgtctttct aagcaattgt gcaatttctt tatcagcagc tgttattcca gctttaccat
    11881 caactataaa aagtattaca tgtgacatgt ccattgcaag catggcttga tttctcattt
    11941 gagataatat tatatcttcg ctatcaggtt caattcctcc tgtatccact aatgtaaaat
    12001 atttatctaa ccattctact tcagcaaata ttctatctct tgtaactcca ggtgtatttt
    12061 caactattga tatccttttt cctgcaaatt tattaaatat tgtagactta ccaacgtttg
    12121 gtctcccaac tacagctaca actggcctac ttatactcat tttatttctc cttccatctt
    12181 ttgttttcta ttttaaaatt ttatccacaa aatcttttcc ttcattcaaa caagggataa
    12241 tttttattct cataagttct tctaattgat ttaattcaat attatctaag aaaatttctt
    12301 catctgcttt tagcatactt cttgttatat aaagagcttc tcctaattct ttatcttcaa
    12361 gttgttcttt taaatcctta gctgttaaaa gacctgatac agttattgtc tctccaaaaa
    12421 acttgttttt gatttcatat acatttactt gaagattttt aaacttgtcc atcatagcat
    12481 ctgccatact ctgtataaat tcatatgcag aatgaccagt agctattgat actttcttct
    12541 ctctttttag aatcttctca ggcaatatat ttagatactc ttcaatctct gtttttaact
    12601 tacgtatcat acctacacca tcttcaaact gtaaaaaacc ttcatattct tcatatccag
    12661 gcaattcact attagatagt atataaaatt catctgataa aaatgcaaat cgagtaccta
    12721 atttttcaag atatttctgt tgtatttgat gtatttgctc tatagtttta cttgcgctct
    12781 tatcattaaa tatatttaat tctactagat tttctctatg ctttgtaatc ccaactggaa
    12841 ctatcgcaac actgtttaca tacggataaa gttgagctag ttcttttatt gttctatcca
    12901 attcctttcc atcatttata cctggacata aaacaatttg acagttcatt tctatatgag
    12961 tatctgccaa tctcttcatt ataccatata attttcctgc aaatttattg cttatcattt
    13021 tttgtcttaa ctctggatta gttgtatgca cagatatatt tataggactt attctatatt
    13081 ttataatatt atttatatct tcttcactca tatttgtaag tgtgacaaaa tttccttgta
    13141 aaaaagataa tctcgaatca tcatctttaa aataaagagt ttctctcata ccttctggca
    13201 attggtctat aaaacaaaac atacacttat ttctacagct tttagcttgg tcaattatcg
    13261 gatttgtaaa ttcaacaccc aaatcttcat catagtcttt ttctatctcg tatatgtaga
    13321 cttcgccatc ttttttttgt atttctacat ctaaatattc atcacttagt aagaatctat
    13381 actctattat atcatgtatt ggctgttcat tcacagatat aagtaaatct cctacctcta
    13441 tacctatttc ttctgcaata ctatctttat aaaccttact tataatatta tttacttttt
    13501 ttacatttac ttccaatatt ttcaccactc ttttgtattc atcaatgctt attataatat
    13561 attttaatat gcaatttatt tatttattat attttatgat agcattttta agcatttcat
    13621 gtcataataa cacattttaa ttctaatagt caatataagt aaatagctat aaaatagatt
    13681 agaacaaata atattcaaat ttaagtttct taaaaatttg aatattattt gttcttaaaa
    13741 aaattttata aatttaatgt tttactatga ttaacgtccc atttgtcata tcatgaacca
    13801 ttccacctac acactttgac atcaacaatg ccttattttg taagtctttc tcatcatttg
    13861 cataaaatat tggacaacct ccaccatttt tcatattctt atcaagtgta actatagcta
    13921 gggtatattc atttaaacct atatccattc ccatcttatg cacttccttt ctttcctatt
    13981 ttataatttt ttagtgataa gttttttcct ttagaacttg aaagtattgg gcatgacttt
    14041 acggcttcca ttactttttc cacattctta tctactggta aataagcaat cattatactt
    14101 tcatcctctt tattccttct aggtaatggt acgaatgaag gttctccata atctccatat
    14161 aaacctaacc ttgaatatat attgtatact attgcctgtc tttgacctga gtcaaataat
    14221 atccctgcat tagcataatc tttattttta ggaattattt gtattcctac acctctatta
    14281 atatatactt ctctatcact ttttagacct atatttgtta ttccctttaa atctcctacc
    14341 ttcaatatag actcatctac aaaactaatc tcagcaggca ttacatcagc tatgtctcca
    14401 atactttttc tagtaagaag tttttttaat ataaaggcta acactaatcc acaaattgaa
    14461 cttattacca aactcattcc ttcacttatt ttcgtttctg caagtattac ataatacaat
    14521 cctattgtta aaaaagatgt aactatacac atataatttc ttacttcata ggttctagct
    14581 atctcttcta tgaatgcagc tcctctcttt acaagttgaa cttcctctaa gttttgcaat
    14641 gtatttcttc tatttgctct cacttgtcta aattgctctg ctgctaggga taaaaaagtt
    14701 atagatgtat aagaacgatt tataagagct ggaaccaata atgctcctaa tgaagaagcg
    14761 acgaatgcta atataagttg agatagtaaa acatttggtt gcgttggata ctgtttttgg
    14821 tctaaattca acattataat tctagatgtt ataccaataa taacagcaac aaaaaatact
    14881 ctatccatta aatcactcct aaaatattta atttgaaatt ttacatgtaa atctacaaag
    14941 tctttctaga aaaatcactc tgctttcctt ttgatgtttc tatgataggt gtacttttca
    15001 ctacatctat catgacatct atatctttga gtattggcat atatggtata accacagtac
    15061 ttttttctaa attggtctta gatatagcaa caatatcaac ctcatctaca tctctatcta
    15121 tccccatatg aataaataga ttatgtatta tagcttgtct ttgccctata tcatttacta
    15181 ttccaaatgc acctaaatct cttggtataa cttctatggc cagacattca tttctatact
    15241 tttctcttgt actttctaga cctatgttag ttattattac accatttacc attaaaatag
    15301 gtccttcaaa acttattttt gcaggaacta tatctgctat atctgctata ctgttccttc
    15361 ttaaaaatct tctaaaaatc aaaccaacaa tagctcctga cacaatagct aggattgtgc
    15421 aataaaaaaa gctaaggcca tactttcttg caaaaacgat ataaactatc gaagatacca
    15481 gtgcagaaaa aagacttata taacttctag attcatacgt agatgctatt tcttcaacgt
    15541 aagcgtctcc ttttggtact aattcttcat tatcgatatt ctttagtgtt attctttctt
    15601 gttctgcaag accttgaaac tgttgtattg ctactgcaaa aaatgtcaag gctgcaaact
    15661 ccttatctat aagtgcaggt aatgctatag cacctaacga agctgaaagc ccagatataa
    15721 ttatctgttc taaataatct tgtggtcttg atgggtattg tttgtctgta actcttaaaa
    15781 ctaatcctct acataatatt cctacaacta atgcaactat aaaagagtgt ctaaataaat
    15841 ttgcattcaa taaactttct tccattttct cagctccttc tcttatatag tttgtgcaaa
    15901 aaacaaaaaa aattcccttc tatttaagga aatttttttg taatattgta actataaatt
    15961 cgctaccaat gccaagttca ctttttactt ttatacatcc atttagtgat ttgactatat
    16021 gctttgttat agccaatcct aaacccgttc ctcctacatc cctacttctt gctttatcta
    16081 ccctataaaa tcgttcaaat atgcgttcta catcttcttt tggtatccct acaccattgt
    16141 ctataacttt aattacgatt ttttcttcat cttttaacac tacaacttgt acaatcccat
    16201 tatcttgggt atactttata gcattatcaa ctaggtttaa gaacacttgc tttatatagt
    16261 ctttattgga tagtatactt attgatttat catcacattt atataaaact tctatatttt
    16321 tttcactagc tgaatgttga gttatttcat atacctcttt aaatacatca tatactacaa
    16381 cattttccat aagaagagta tctttatttt ctacaaatga taacagcaat atatcatcaa
    16441 tcaacctttt taatctatct gattcgcttt ctattatttc taagaatcta tttctagtat
    16501 tcacatctat attttcattt gactttagtg tttcaacaaa cccacttata gatgtaagtg
    16561 gtgttttaag ttcatgactt acatttgcaa caaaatcact tctcatattt tcaagtttaa
    16621 cttttttagt aatatcttct atatttacta tcgaacctat tattacgttg ttagtattct
    16681 gaagataaac tgggtctact tttatcttat atacgatatc atctttagta gtaatattag
    16741 cagtttcatt atctttagaa ccaataaatt gaagtatttg ttttaatatt tcttcttctt
    16801 ttattacaac attaatatta tgaccttcaa ctaattgatt tggttcactc tttatcattt
    16861 cttttgcttc atcatttatc agaagtatat ttccatttac atctatagct aaaattccat
    16921 gagatatact ctttaatata gaccttagct gtaaatgttt atactgtact tcttctaagg
    16981 ttttatccat attctttatc atatgattaa aatttctagc taattcgcca agttctcctt
    17041 tggctgatat gttaagccta gcatgatatt cattattact tacttttttt gagacgtata
    17101 taaactcttt taaatatttc cttaatgtta ttgtgtatct tacagctaat ataacaatgg
    17161 ctatggacaa cataacaata aaaaaatata tactatttaa atcttccaca agataacact
    17221 cctaaaatat aaccttttta atctattttg tatcctacac ctcttatagt ctctatatat
    17281 ttttccgatt tatcttcatc ttctattttt tttcttaaat atcttatatg aacatctact
    17341 gttctagttt ctccatagta ttcatacccc catattttat ccaaaagata atttcttgaa
    17401 agtacttttc ctttattttg aattaataat tttaacaatt caaattcctt aagagttaac
    17461 tctatctttt cagagccttt ggtaacttca tgttttgata aatctagttt taaattacct
    17521 gtagtaagta tattgttttc ttcacctaag ctagtcaaat tatatctcct taaaacagaa
    17581 ctaatcctag ctaacaactc ttttatacta aatggcttag ttatatagtc atcagcacct
    17641 atttcaagcc cttcaacctt gtcattttcc atatttttag cagtaagcat tataacagga
    17701 atatttttta agtccttatc acttcttatt tttctcaaaa cttctattcc acttatattt
    17761 ggtaacatcc aatctaaaag tattaaatct ggtttaattt ccttagcctt tataaatccg
    17821 tcaaatccat catatgaata actaacttcg taatttgaca cctccaaatt gaattttaat
    17881 agctcaacta tatgcatttc atcgtctata acaagcactt tagtattcat taaaaagctc
    17941 ctctctattt tatctgtagt accgttccta ttcgttctga tgccttatta tgttttctat
    18001 aagagtggaa tttatctgct ctacaactag tgcataaatt taaatttatt atattttctt
    18061 ttttaactcc actacatcta agcatatact cattaatttt ccataaatct aaatagtaac
    18121 ttccctcttt tattatatag aacttttcat cattatttgt aagaattgtg ttaaattttt
    18181 ctactaaatc ttcagacact tcataacaac atggtccaat tgatggccca attatacata
    18241 ctaaatcttc aggaactgtt ttatagcatt cagacattaa ttttattgtt ttatgaccta
    18301 tattactaaa agtccctctc caacctgcat gagccagtcc tatggcttta tttttagcat
    18361 ctataattga tataggtaca cagtctgctg taaacagtaa aagtggtact ttttccaagt
    18421 ttgttataag tgcatctcca tctcttcttt tccctatagt atctttattg actatattaa
    18481 ctatatctga atgtatttga gaattactag ttagattttc aaatgtcaaa tcacattctt
    18541 tacatacttt taacatatct tctctatttt ttgcatctat attcttacat gttataacta
    18601 gatttacaga atttaatttt tcatcaagtt cttcacaatt accacttaaa ttaacatact
    18661 ctttaatatc ttgtacattt tttatattta tataatcttt catcatttgt ctcctttttc
    18721 tatcagtata cttttaagtt catttacaaa agtatttata tctttaaatt gtctatacac
    18781 agaagcaaat cttacatagg caacctcatc taactctttc aatttatcca ttaccatctc
    18841 accgattttt ttggtttcaa tttcttctat aaaacattta tttatttcat tttcaatatg
    18901 tacaacaata ctttcaatct cgtcaataga aacaggtctt ttttcacatg cttttagcaa
    18961 tccatatttt atcttttctc tatcaaaata ttctctacta ttatcctttt taatgaccat
    19021 taaaggagtt gtttctattt tctcatacgt agtaaacctc tttttacatg attcacactc
    19081 acgtcttctt ctgatagatt ttaaatctgt atgtctagaa tctattacct ttgattcttt
    19141 ataattacaa taaggacatt gcatctatat tcctcctttg tttaactata tctcaaactc
    19201 atctaagctt aattctgaac ctatatttac tattattgta tcacaaccta ttttaagtat
    19261 atcattccaa aatataactt cttcatcccc tcctcttgaa aaaaaacttc tacttccatc
    19321 tccaaaaatg gtaaatgaga ctaccttacc ttcgtgaata tccatgtcta tgtctattat
    19381 aaaccccatc ctttttccat tttttacatt tataatttct ttttccatta tatcagaaac
    19441 tctaatcata ttgtactcac cctttcttta aaaataaata tgtatcgaag taaaaaaaaa
    19501 tgacctatat aggtcattta aattaaaata atgtttacag tccatggatt acttatacat
    19561 attttctcat attctttaaa gcattttttt caattcttga tacttgtgct tgagatatac
    19621 cgatttcatc agcaacttct atctgagttc ttcctttgta aaaccttaaa tctaatacca
    19681 acttttctct actatttaat ttcttaatag cttctttaag tgatatttct tgcaaccaat
    19741 tttcatcagt atctttttta tcttgaacct gatccataac gaatattgca tctccattgt
    19801 cttgatatac tgggtcaaac agagatattg ggtcttgtat ggcatcaagt gccattacaa
    19861 ctgattctac ttctaattct aattcctttg ctatttctga tactgtaggt tctttagaat
    19921 ttgttctaat taatctttct ctaacttgta gtgccttata tgctatatct tttaatgacc
    19981 tacttactct aattgggtta ttgtctctta gataccttct aatttctcct ataatcatag
    20041 gaacagcata agttgaaaac cttacatttt ggcttaaatc aaagttatct atcgctttta
    20101 taagaccaat acaacctatt tgaaataaat cgtctatatt ttctcctctg ttgttaaact
    20161 tttttattac actcaagact aatcttaaat tccctcttac aaactgttgt ctggcttctt
    20221 catcaccatt ttttatttgt aataaaagtt ccttcatttg cttattttta agaactggaa
    20281 gttctgatgt attaacacca catatttcaa ccttattaac ttgcatatat tttcagtcct
    20341 ctctcaaaag tattcatcta ttgaaattat ttacatttcc aattttttta tactttttaa
    20401 gaagaattaa tttagcatta tacaaatttt ttcatttctt tttgcaacct tgagattatt
    20461 ttcttttcaa gtctagatat gtaggactgt gatattccaa gcattccagc aacttctttt
    20521 tgtgtttttt caataccttt atcaataaga ccaaatctta attccataat ttgcttttct
    20581 ctgtcactta atctgtcaag tgccataacc aacaaatctc tatctatttc ttcttcaatt
    20641 attttgtata tttcatcatt ttctgtaccc aatacatcag ataataaaag ttcgtttcca
    20701 tctaaatcta tatttaaagg ttcatcaaat gatacttctg ttttcttttt attatttttt
    20761 cttaagtaca ttaatatttc attttctata catctcgaag cataagttgc caattttata
    20821 tttttattca gtttaaaagt attaactgct tttatcaaac ctatagttcc tattgaaatc
    20881 aaatcttcta catctatacc tgtattttca aattttctcg atatgtagac tactaatcta
    20941 agatttcttt ctattaaaat tgactttaca ctttcatctg tttctagctt ttgtaaaagc
    21001 tccatttctt cttctggttt caatggagga ggaagtatat ttgcccctcc catatagtat
    21061 attccctttg gctttattat ttttaattta atacctaaca tagtaataaa gcttattatt
    21121 ctttctttca atcgtaacat tccttgtccc ccttaaattt tcacctaaaa tccaggcaat
    21181 atatttggat tcattattgc tccatattct ctatcattaa aatttgaaat accaagtatt
    21241 atatttccta tcttttgctc atctacttct atatagtcag cttttaagcc tattattatg
    21301 cttgtcttat tacttccagc atgtttataa ggtattattc taactctacc tgaagtttta
    21361 tcatctaaac ttcctataat ttcttgtgct ttcttcatat ctatatcttc ataattaata
    21421 tttaatagtt tttctggaat aaatccttct aacacactag acttaactat tattacatca
    21481 ctttgactta ttgggtcttt taacaaatta ccactatcta ctaaagcctt acagcaaaaa
    21541 cttttttcta gtaagtttat atttatagtc tttgtaagct ccttaatgta cttaagcatt
    21601 ttcaaatctt tataaatgta ttttaataat tcacaactca cataagtaca tgcaattaag
    21661 aaagatattt ttaagtgact tattcctgta aaataaatta taaaataagt gcttccagaa
    21721 ataaaaatgt ttactagata aaaaactaac gctacatgaa cataatcttt tttgctctta
    21781 cttctaaatg aaattaaagt tattatactc atgattatta ttttaaatgg tacagtaaat
    21841 agtatattca ttgatggata caaataagca acagaatagg cacctcctaa actagccccc
    21901 aataacttat tttttttagg attatatctt ttagtaagaa tagaagtaca acttataata
    21961 atataattta ttactaggtt ttctataaca tagtactcaa tatacaccat gtatcccccc
    22021 ttaaaacctt taaacatatt ataagatagt atgtacaaaa ttttatgtca cttttgatgg
    22081 tcgaatccaa aacaaattct atttaaaaag aacaatgata tatgtcttat actttatgtc
    22141 gtcaaaagat atttttttaa tgccaaacaa atagactttt ttgtagaatc caatatatct
    22201 aggtagaagt tattcgctct acttttggta tatttacaaa aaaagactac ataatttaat
    22261 aatatatcaa gtaaatcttt tacttatata aaatcaaatt atatagtctg taaattcaaa
    22321 tataaattat tgtgctagta atccatttgc atattttgca gattcattta gtgcttgttc
    22381 tggagttatg tctccagcta tcatcatttg aagttgtttc cataaatatt catatatctc
    22441 tactccatga ggtccaactg tcaatggtct atacatatgt ttatctcttg tcaccatttc
    22501 ttcaaatctt gggtctcctt ggtatttttc acctttagca actggagctc taggtatttc
    22561 tttgtggaaa gcttccattg attctttgct tagcatatac tcaagaagtt taaatccaag
    22621 ttctttattt ttacatgctg acattaatgt taaatcatct actgaagcaa aacttccaac
    22681 tgtcttatct tctaatgatg ttacatatcc ccagtttaaa tccgggaatg atttatcaaa
    22741 tgtacttgta gcagcagagg atagcattat agtaaatgca gcttttcctg gtccaaatac
    22801 actttcaatc atttcattac tatcttttga taaagcatct tctggaatat actttttcat
    22861 atcatttata aagtttgcag ctttcaagcc ttctgcatta ttaaatttaa ctgattttaa
    22921 atcatcatta tatatatctc caccagcttg ccataaatac ggataccagt tccagtttaa
    22981 gcttccaaat actttagaac cccaaccttg tgcaagaccc cactggtcga tttttccatc
    23041 tccatcagta tcttttgttg ctttttcaca gattctttta aaatcatccc atgtttttgg
    23101 aggtttttct cctaattttt ctagtatatc tttattgtag tacaatacgc ctggattagc
    23161 agcttctata ggtaaaccat aaataccacc catcattttt gcatcatcta agtatagata
    23221 attatctgaa gttcctgatt tttctaaata aggtgttaaa tcttctaccg cacccatttc
    23281 tataaattga ggaaacatct ctgcatacat gtatcctata tctggacctt cacctgcact
    23341 tattgctgtt gcatattttt ctgcgtagtt atcccatggt actatctgaa attcaatttc
    23401 acagttattt tctttttcaa atttttcaaa tatcggcttc catgcatctg catcatggtc
    23461 tgttaatggt gcagaccata caactaattt ttctttaccc tctttgcctt tagaatcttc
    23521 tttttttgaa catcctgcaa gaattgatac tgatagaatc cctaccataa ctaaagaaag
    23581 aacctttttt agtttaatca tgcttaatcc cctttcagac tttaatttgt ctttttcctc
    23641 aaatgtttac atttaattca gatttaatat taacaaataa gattactctt gtctaatcat
    23701 aaaaaactat actaactcct ataactatat tttttttcta tacctattag atttaattca
    23761 tactaaaaac ttacttttta aattttatca atatttaaaa atttttttaa gtctagccac
    23821 aaactaacta tctaaattga gcaaaataaa aagaagtcta ttgacttctt tataagctta
    23881 catattatct tcttcttctt aggaatgtag gtatctccat gctctcatca tcatcttctt
    23941 caattatact tgccttttta ggaggctcta ttttttcctc agcaattact tcttcttcaa
    24001 tttcttttac agcttgtttt actgttgtat ttaatgaaga acgtatgctt gatttaggtt
    24061 tagtatctaa atctaaggca ccattttgta atccttcaaa tcctgtcgcg attactgtaa
    24121 tcattatttc atcacctaaa tcttctttta tagaagctcc aaatataaca tttgcttctg
    24181 ggtcacagga ttccataact aaagttgatg cctcattaac ttcaaataat cctaagttag
    24241 gaccacctgt aacattaaga agtactcctt tagctccttg tattgatgtt tctagaagtg
    24301 gagattgaat agcttgtctt gcagcatcaa ttgctctagt ttcaccacta gcactaccta
    24361 tacccatatg agcaagtccc ttgtctttca ttatagtagt aacatctgca aagtccaagt
    24421 ttattaaccc ttcaactgct ataaggtctg aaattgattg tataccttgt tttaacacat
    24481 catctgcaac tgcaaaagca tctaacattg atgtattttt ttgtactatc tgtaaaagtc
    24541 tatcatttgg tatcgttata agagtatcta cttttgattt aagttctgct attccacctt
    24601 cagcgttctt cattcttatc ttaccttcaa atgcaaaagg tttggtaact acacctactg
    24661 taagtatccc catttctttt gccaagcctg caaccactgg agcagctcct gtaccagtac
    24721 caccgcccat tccggctgtt acaaagacca tatcagctcc ttgaagtaac tttactattt
    24781 catctttact ctcctcagca gctcttttcc ctacttctgg atttgctcct gctccaagtc
    24841 ctctagttaa tttttctcct atttgaactt tatattcagc ttttgatgta tataaagctt
    24901 gtttatctgt atttactgat ataaattcaa cgccttttag ttgagcttct accattctat
    24961 tgacagcatt gtttccaccg ccacctacac ctattacttt aatttgtgca cattcttcta
    25021 attctacgtc aaagtttagc atcataaacc cccttctctc atgattcaaa gttatcgtat
    25081 gtattaatta tatcattttc ttcttttatt ttgttaacct ttaagtaaca tattccacaa
    25141 aaacgtaaat tttccttttt aaatttctta cttatattgt caaatattac tctttaagta
    25201 taaaataatt tacgtatata ttaaatgctc tttaattttt acgttttttg ttcataatat
    25261 tactaataat atatcgtcta attatagata agttattaaa caatctcata ccaaaaacta
    25321 atacagcaac atagtaaaga gaaactccta acttttctcc tatataagtc aataatatag
    25381 ccaatatagc attacctatg aaaccagtaa taaaaattac attatcatag ttatcttcaa
    25441 aattggattt tatcgctcca aaaatagaat ccattattgc aagaatagct actgacatat
    25501 atatggaata atccatagaa tatgtaaatg gaatatagta acctactact acaccaaatg
    25561 ctaatcctcc taaaacccat aacataaatc ttcacctctt tattttactt tgaaacacaa
    25621 ctacattaca atccttttta ttaatttttt ttactttttc tttatttttt tgtatttttc
    25681 gttttatttt gcaaataaat tcactttatt tccattattt tcctgaactt ttatattaat
    25741 tccatatata tccttaagag atttagcata tgattctgga gagtttatag ctgcactcaa
    25801 taaatctata tctcctatag cttttattat aaatggttgt ccatatgtag tatcatttac
    25861 tgtaatagta gctcctgaac attttatctt acttgttgct agtactcttt ctccatttat
    25921 agaaattgct cttgctccag ccttttttaa atcatttaaa accctcaaaa tatctatatc
    25981 atgtataatc aaatcgtttg gattctgtcc gtcttttaac tctctctcac tatccctcat
    26041 agtaatagtt atgcctggcc ctgtaacagt tgaataacca cttaattctt taacttcttc
    26101 aagctctttt tgcataagtg tttggataga ttcatttcca ttcttttttg cttctttata
    26161 ttcattcaaa gtttttttgt tctttttaag agtttctttt aagtttttta tttctttttt
    26221 tgtattttct acctcacttt caatactttc agtttgacct aatgttatgt atactctatt
    26281 tgggtctagt gattttatat aagttgatat gaaaacgcct aatatgaatg ctcctaatat
    26341 aactattttc tttttcatac tattatttcc cctctgcttt gtttatatca ctatgaccat
    26401 ttatttctat attgtcttct ttggtcactt ttactttggc attataatat gtttctattt
    26461 cccagacaat accatacttt atattaagtg ccgaagccaa tgtatcagaa tcaccaattg
    26521 cttttattat aattggttct tttatgacag tgtcattcat ataaagcttg tcttctttta
    26581 aatacatata tgtattagaa actattctct ggtcgtttat agatatggca cttgcttgtg
    26641 ctgaatttaa tttatttatc attgataata ataaatcata attatatagt atactatcat
    26701 ttttatcaga gtttcctaag tcttttgtag aatttatctc aatttttatg cctgttcctt
    26761 caacatctgt atatccagct aatgtttcat atttttctat ttctgactta agtatgtctt
    26821 gttctccttc attgtttttg cctctataaa tctctatatc tttcttcaca ctattaactt
    26881 ctgattgtag attctctttt tcttttttta aagatttaag ttcttctgta agttgctctc
    26941 ctcttttaaa agttgtcatc cctctatttt ctatattaat aattttaagt tgtaaactaa
    27001 caagaacacc caatacaata cttcctatga ttatactttt atttataaat ctttttttca
    27061 atatatcact tccttacaat tgtctatcct tctggactat acactgccaa ctttccatag
    27121 ttaagattta tagtccctcc attagtattt ttattttgca ggtcaatcag aattttactt
    27181 accctagata tattataatc taagttatca tcattagaaa gtaagatttt tatattactt
    27241 cttgtaagca tttctatatt gctttctttt tttaagttta cataatttat ttttctataa
    27301 attccttctt cttttaaata atttaaagtt ttaaatacat tctccttagt tttataattt
    27361 ttaaatttta tagatttatt atcatcaatg ctataatcta catctactat caagtctttt
    27421 ttactttcat tagaacctct tagttcttcc aataaatttc cttttttatc tatataacaa
    27481 taattatctt catcttttaa tactgcaaat atttcttttt cttttaaact tataattatc
    27541 ttattgggaa gttttctttt tatttccaca ttttctatat atggattttt tataagttta
    27601 tttttcatat ctttaaaatt gtatgcaaaa atattttcat ttagatttac atttagttct
    27661 ttcattatat ttgatttggt caccctctta tttccaatta catctatttt ctttacatca
    27721 aataaatcac tttttacaat tatacatata caaaaagata acataagtat aaaaactaaa
    27781 actatcatga cattattcgt atttaacttt cttctttttt tcaaatataa tcaacccctt
    27841 tggttaataa atacaccttt agagcttgtt tttcctacaa aaaaattata atatttaaag
    27901 tcaaattttt gcattttatt acataacatc caaataaggt attaaatttt ataaataaat
    27961 ca
//
LOCUS       DAJMZY010000045        27888 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.045, whole genome shotgun sequence.
ACCESSION   DAJMZY010000045 DAJMZY010000000
VERSION     DAJMZY010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 27888)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27888)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27888
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.045"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            28..879
                     /locus_tag="OE968_001929"
     CDS             28..879
                     /locus_tag="OE968_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase"
                     /protein_id="HCP7219209.1"
                     /translation="MKNIISAKELISKLEKNDNLVVIDCRFDLINRTYGIDSYKKGHI
                     KGSFILDIDKDLSSPTKEHGGKNPLQDPLILKEKLEKMGVDNDTTIVTYDDGDLNGAC
                     RLFFQLKHLGLKNVYVLDGGITSFVKEGGELEEKVNIPSCTGKEIRPNINNGLVVPME
                     YVKSKLYKKDTVIIDCRANERYQGLVEPAYSKAGHIPSAKNYFCKDLIKSDFENGSLK
                     DIEFLKKFFKDLNNYDEVILSCGSGISACVNSLALRELDIPHKIYIGSFSDWISYDDN
                     EIKTGQE"
     gene            complement(1012..2625)
                     /gene="ggt"
                     /locus_tag="OE968_001930"
     CDS             complement(1012..2625)
                     /gene="ggt"
                     /locus_tag="OE968_001930"
                     /EC_number="2.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyltransferase"
                     /protein_id="HCP7219210.1"
                     /translation="MKFNAYQHKYSSIRNVVYAKNGAVATSTPLASQAGLEILKKGGN
                     AVDAAVATAATLAVVEPTSNGIGGDAYALVWIEEEKRLYGLNSSGFAPENMELKNYNN
                     MKEMPKYGFGAVTVPGIPAAWSELNKKYGKLSLMECLSPAINYAREGYVVSPNVAKVW
                     KKSYELYEKELIGEEFKPWFDTFSKDGKAPEAGDIFICEEQASTLEEIANTQAESFYR
                     GRLADKIDEYSKKFNGAIRKSDLECFYPTWVEPISTEYKGYKIFEIPPNGHGITVLMA
                     LNILKELELEGNIENVEDIHKIIESLKLAFADSKTYVTDIEHMKVKIQELLSQEYAKK
                     RSLLIDNKEALYPTAGEPYCGGTVYLCTADKDGNMVSYIQSNYINFGSGIVIPRTGIA
                     LHSRGNNFNLDPKHHNVVKPFKKPYHTIIPGFLGKEDKAIGPFGVMGAFMQPQGHIQV
                     LTNMIDFGLNPQEALDAPRWQWIKGKEIEVEPEMPKHIIDSLIEKGHEIKVIHDTVDM
                     GRGQIIFKTEQESYICGTESRCDGHIAVY"
     gene            complement(2850..4787)
                     /locus_tag="OE968_001931"
     CDS             complement(2850..4787)
                     /locus_tag="OE968_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCP7219211.1"
                     /translation="MTLFRIAMQNVKNSFFNYLMYFISIVFSVFVFFSFKSIEYNEAL
                     SSLGEKTRMSINTSSIVIVVFVFLFIYYSNSFFFNRRRREVGTYSLLGMRKNQIGKIF
                     LYETFLMGIVAILIGIFLGLLFSKLMTMMLVKLMNEMIVVNMNLSIKALVQTLAVFLI
                     IFIVIGIRNTIVIRNKRIIELFNKYPEKYKFKKFIKLKCVLGVLLIAISYLMSISYFI
                     AENIMLSVFILVTIIPGTFLFFSSTMYMIIDAVKKRKSFYYKGQNLIAFSELGFKLKS
                     NSSVLAVIAILIATSVTMLGFTISLYYDIDRNISENYKYSYTINLGNSYVNNEIDKLL
                     YKYKKDNKIIFDKIIELIDKDINIEMYYKNRNSYIEDRTSVDIIRESDFKKLRQYQNN
                     NYEELTSKESVYYVSDSYKKIFFKDFEIEKINLHIKDANEYDINLFKVQKSILEPEIN
                     SQATFDLIVVKDDVFNQLKLHGNSRLIRLIDIKNEKKELDLTLKLKNIVSENMKFTYP
                     FNFTSSIESYDNLIKLSGLMLFIGIFLSVVFLLCTGSIILFKQLSNIYDDKERYIMLI
                     KLGANNKDIEKIISKQLKVIFLMPLVVGTVHNLFAMSIAQKFIPRSLLVPIIITLVIY
                     FIGYFIYYFLTLKYALNMIKE"
     gene            complement(4774..5541)
                     /locus_tag="OE968_001932"
     CDS             complement(4774..5541)
                     /locus_tag="OE968_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003722224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCP7219212.1"
                     /translation="MEEILSVENIKKEYGRKGSKHEALRGITFKVYKGEFVGIMGSSG
                     AGKSTLLNIISTIDLPSSGDIYINGKNTIKMKQNELADFRRDNLGFVFQDSNLLDTLT
                     IKENIMLPLSLKNERVSVIENRIKEISKELNIESILDKYPGEVSGGQKQRGAVCRAIA
                     TKPSLVLADEPTGALDSKSARDLLNCLLKLNKDSNKTILMVTHDAISASFCNRILFIK
                     DGIIFTEIVKGESNREFYNKIVNTVSLIGGVNKNDFI"
     gene            5829..6503
                     /locus_tag="OE968_001933"
     CDS             5829..6503
                     /locus_tag="OE968_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCP7219213.1"
                     /translation="MFKIMVVEDDVSLKNIIAKCLTKWGHDVHQIENLENIIEEFKNY
                     NPELVLLDINLPFYDGFHWCNEIRKISKVPIIFISSRNSNMDVIMGVNLGADDYIQKP
                     FSVDVLVAKVNALLRRTYNFVDNNSNQIIHNGVTLDLSTATINYEDNTIELTKNEIKI
                     LHELMKYKGQIVSRNKLMKKLWDNDWFVDDNTLTVNVNRIRSKLNEIGLEDFIETKRG
                     LGYIIS"
     gene            6527..7531
                     /locus_tag="OE968_001934"
     CDS             6527..7531
                     /locus_tag="OE968_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HCP7219214.1"
                     /translation="MSFKDFLKDKLGFLVYNFTFLIFTVSVIIFSPVDVFLTDTILYI
                     LVVNVVFLFLYLFISYIKKNKFLDKIKNDTFKINMNDIELARCKNEEKIYLNIIKNHQ
                     YQCNNIINNNIEKFEENKEILNMWVHDVKIPIAIIKLILEQNENLIDEKISDDIDSEI
                     FRIENSVEKILYLSRLEDFHKDFLIQEVNIEKIIRNIIKKYSKYFISKKIILDLNNLN
                     FKVLSDEKWLYFIFEQLLSNSLKYSSLGDNISIYCKRTKNYLQLRVEDTGCGIKKEDL
                     NRIFNKGFTGNNGRNNSKSTGLGLYLVKELCDKLGHKIDVDSEYNQYTKFTITFKCDL
                     "
     gene            7643..8872
                     /locus_tag="OE968_001935"
     CDS             7643..8872
                     /locus_tag="OE968_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HCP7219215.1"
                     /translation="MSFLKKFKNKRFRNNSFKSNNFRNSSFGSSGFKSKNKGFKNNPF
                     KNKRFKIYAGIAVIILLILGVLAYVDSKNTELQANENFIETYTIPENEKIFINGMVVP
                     KQTKDFNISGDYELSDVNVTNGQKVNQGDLLFTAKNPTIIAEIDSLKSQLSQYKKQKI
                     SLSDIAENKDAIASINAQITALNSQIASLDKKAYDRVTAPFDGTVYLNDQTGNPDQPV
                     SFMTIQGLEFYMKGQASEQDLPKMKIDQMVNILVFSTDQKLTGRISFISDKPSTPNTE
                     MGAQQNTLSYYDINIAFDNQEGLVNGFHLQASLEVANSSFKIPASCVLKDNKHSYVFK
                     DLDGILKKQIVDVASQNDDFAVVRGGLEQGDIIIKHPTKEMKEGDPVQGDGVTAGSNN
                     GDTTPNKKVEEVTMDVN"
     gene            8880..9554
                     /locus_tag="OE968_001936"
     CDS             8880..9554
                     /locus_tag="OE968_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCP7219216.1"
                     /translation="MLIKLENIQKYYKVGKDELHVLKSLNLEIESGEFVMIMGKSGSG
                     KTTLLNILGFLDVFDEGRYIFDGTDVTNLSENERSVFRNINIGFVFQQFNLIETLNVY
                     QNVELPLIYNKALKKSNREEIVKDKLSSVGLLDKLKQKPLQLSGGQQQRVAIARCLAN
                     DPQIIFADEPTGALDSETSREIMELLTRLNKQGKTIIMVTHDQDLTKYATKVIRLKDG
                     VFTSEV"
     gene            9557..10789
                     /locus_tag="OE968_001937"
     CDS             9557..10789
                     /locus_tag="OE968_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCP7219217.1"
                     /translation="MSLLKNSLANLKGHKLRVFVALLWIIIGITSVILVSSIGNGFQK
                     EIKKSVNNVNPNKTTISFESADNTGLTDDMSIFLKPFNAKDLEELSFVEGVERIAPSR
                     DGFNLDSVYSSQASFDKKTTYVDVGPVKKDSKINLICGRDFSLDDEKRKVILLTLQST
                     SEIFENPEDALGHGININGTIFEIIGVLDDSQQNQAGGFFGGYQDMQFTTSLVPKKAF
                     DTLMSQNSYSNEIYQLDLVSSKGYNVNEVANNVIAKLYEMHPGINGSYTTPDPTEQTA
                     YLESINSNVNKYVSIITVVAMFVGGIGVMNIMYVSVMERQREIGIRRAIGAKPRSILF
                     QFLVEAVFITVCGGILGTIVGFAATNYVSKYIGFEAIPSLNSLFYAIVATILTGVVFG
                     LIPAFKASKLDPIKAIYK"
     gene            complement(11075..12340)
                     /locus_tag="OE968_001938"
     CDS             complement(11075..12340)
                     /locus_tag="OE968_001938"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HCP7219218.1"
                     /translation="MILIKNGRVIDPKSQRDENIDLIIKENKIYKIGKFDESDEYEKI
                     IDASGNVVAPGLVDVHVHFRDPGFTYKEDIESGAKSAARGGFTTVICMANTNPIVDNE
                     DTFNYVKEKSKNACINVLQAAAITKGFEGKELVDMEALKKAGVPGFTDDGLPLMDSNL
                     IMEAMIKAKELDVPLSFHEEDPSLVGNPGVNAGKVASELGLKGASSVAEDVMVARDCM
                     LALKTGAKVDIQHISSGVSVDMVRFAKYLGANVVAEASPHHFTLTEEDVLEFGTNAKM
                     NPPLRSKWDRDKIIEGLNDGTIEIIATDHAPHSKEEKDREFIKAPSGIIGLETSLALG
                     ITNLVHKNHLSMMQLIEKMSINPAKLYNLNIGFIEEGAVADIVIFNPEEEWTVESFVS
                     KADNSPFKGKSLYGKVNYTICNGEIVYNA"
     gene            complement(12393..13541)
                     /locus_tag="OE968_001939"
     CDS             complement(12393..13541)
                     /locus_tag="OE968_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF362 domain-containing protein"
                     /protein_id="HCP7219219.1"
                     /translation="MKSVSVRSCKTYNYEEVKLSIEKNLEDIGGIDKFVKKGSKVLIK
                     PNLLMKKKPEEATTTHPMVVKVVCEKLLELNCDITIADSPGGPYNQSSLKSIYKASGI
                     EEVANELGIKLNYDVSDVKIHSEKAHVLKYMDIIKPIVDSDYIINLCKLKTHIMATFT
                     GGTKNLYGCIAGLKKAEIHYRFPTEELFCENVLLDICDYIKPTLTIMDGIVGMEGDGP
                     SAGTTREIGVLLASQNPYAIDVVACKIISLLPNKVATIRGAIKRGYIQEDFSDIEILG
                     EDIKDLIIKNYKIPNVSKDLRLFSVKLPKFLNEPISKLITPKPVVRFQDCIKCGKCKE
                     ACPASTIEIGTKGAIIDLSKCIRCYCCHELCPKKAIDVKRNFVFKYVK"
     gene            complement(13641..14186)
                     /locus_tag="OE968_001940"
     CDS             complement(13641..14186)
                     /locus_tag="OE968_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH peroxidase"
                     /protein_id="HCP7219220.1"
                     /translation="MKKFVCTVCGYIHEGDAAPAQCPVCKVGADKFEEMKGEMVWADE
                     HRIGVAQGVDAEIIEGLRANFTGECTEVGMYLAMSRQADREGYPEVAEAYKRIAFEEA
                     EHAAKFAELLGEVVVADTKENLRVRVDAEYGATDGKLKLAKRAKELGLDAIHDTVHEM
                     CKDEARHGKAFLGLLNRHFGK"
     gene            complement(14409..15353)
                     /locus_tag="OE968_001941"
     CDS             complement(14409..15353)
                     /locus_tag="OE968_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HCP7219221.1"
                     /translation="MQKNKKEGALLKKYFGEIGLIFIAIIWGSGFVATQFALDGGLTP
                     LQIITLRFFLAAIIMNLLFFKQIRANMGKKLLKAGGILGIFLFLAFTVQTIGLMYTTP
                     SKNAFITAANVVIVPFIGFILYRRKLDKIGIISSLVALIGIGILSLEADFSINFGDFL
                     TLICSFGFAFHIFFTSEFAKDNNPMALTAIQFTVAFLMSVVVQTFAGQLKMEAELSGY
                     MGTMYLAVFSTTIGFLFQTICQKRVDGTRTAIILSTEAVFGTIFSIIILKELITAKLV
                     IGSILIFVAIITAETKLSFLKSKKVKLKDSEESSLESI"
     gene            15739..16620
                     /locus_tag="OE968_001942"
     CDS             15739..16620
                     /locus_tag="OE968_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase"
                     /protein_id="HCP7219222.1"
                     /translation="MVKKRKKKTVTLTILVVIVIGIFSMAWADMSRKKEMKETQERLK
                     AERLEKERIEKEKNEPIIGAKKEAVKEYGYDAKIVWDKLNKYDYSNNGEKIVFLTFDD
                     GPSTTNTPQVLDILKRHGVRGTFFIKGDSLERKGANEILKRTFDEGNAIAHHSYTHDY
                     KKLYPNRSLNLDTFVNELNKTDEAMKKVLGKNFSSNVVRCPGGYMSWKNMEPLGNYLK
                     EKNMASIDWNALNADAEGKKKNAQELFEHAKKSSEGKEMVVLLMHDTYGKQETVNALD
                     QIITYFKDNGYQFKILI"
     gene            complement(16681..17889)
                     /locus_tag="OE968_001943"
     CDS             complement(16681..17889)
                     /locus_tag="OE968_001943"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HCP7219223.1"
                     /translation="MKSIDEQMRIIMKGVDDLIDEKELREKLIKSEKEGKPMIVKLGL
                     DPSAPDIHLGHTVVLRKMKQLQDLGHQIVIIIGDFTGKIGDPTGKSKARKALTTEQVL
                     ANAKTYEEQIFKVLDKEKTIVRFNSEWLAKLNFEDVIKLAATITVARMLEREDFKKRY
                     EGQMPISVHEFFYPLMQAYDSIALEADIELGGTDQRFNLLMGRSLQREFGMESQIVIM
                     MPLIEGLDGKEKMSKSLGNYIGIDEEAGIMYQKSMEIPDELIIKYYNLVTDVHPDEVN
                     KIESQLKEGSVNPRDIKMNLAREIVTLYHGEESAKEAEERFKSVFQKGQIPEDIQTIQ
                     VKEDGFDLIEVLVSNEIVKSKSEVRRLASQGGVKVNGEKVEDLSTIVKESELVVQIGK
                     KKFVKIELVK"
     misc_binding    complement(17962..18214)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(18366..19355)
                     /locus_tag="OE968_001944"
     CDS             complement(18366..19355)
                     /locus_tag="OE968_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2232 domain-containing protein"
                     /protein_id="HCP7219224.1"
                     /translation="MIYGGSVLNTTKKLTEAALLSSLFIVVTIIAVSTGFGYAIYLDF
                     IVPVFFCIICLKCDLKYTILSGITSLLIISLVLGNLGTAIWASQSVLLGIMCGYLINK
                     PTMVMDDLVYGSVFGVIVMVFIDIYASTLIGYSFMKEFQGYSKWIYFNGYTNFIYYLM
                     IALFPFGMVFCIYLLSLILGNKLHILDSNSLKKFLIFKNFRNLNQFLCCSKKAFYICV
                     SYLAIFEVLKLLNVKVDSVYLKTIFISITYISVYFIIRDSCMSLQNFIIAKFRKLLYA
                     RILFLIIILLLFFIFDVTVISLIIINAFLNKKINIRLSQSNIVNKQINLLIEK"
     gene            19507..19947
                     /locus_tag="OE968_001945"
     CDS             19507..19947
                     /locus_tag="OE968_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCP7219225.1"
                     /translation="MFKIKHFNDLSLDEFYEIAKSRYEVFACEQKIFSLNDYDDIDKS
                     SYHIFLKENGLICAYARIIPKEYSSYNDVSIGRVLVLSSHRRKGLAKQMMDCAIDFIK
                     VNLHENNITLSAQTYIKNLYLSCGFKEISEVYDEAGIEHIKMRL"
     gene            20274..20501
                     /locus_tag="OE968_001946"
     CDS             20274..20501
                     /locus_tag="OE968_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HCP7219226.1"
                     /translation="MKNLNDIQVKKTVKVEDILSSGNLRERMLALGLTRGAVIDVVRK
                     GPKNNLTVYKIRGSKIALRQEESSLILVSDI"
     gene            20527..22647
                     /gene="feoB"
                     /locus_tag="OE968_001947"
     CDS             20527..22647
                     /gene="feoB"
                     /locus_tag="OE968_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HCP7219227.1"
                     /translation="MGLTHNSTKMSSLKDMFDIDNKEDQFVIALAGNPNTGKSTVFNH
                     LTGLRQHTGNWPGKTVATARGNFKYKNTEYALIDLPGTYSLFALSQEEIVARDFICFG
                     NPDAVIVVCDATCLERNLNLVFQVMELTDKVILCINLIDEARKKGITIDKKLLEDSLG
                     IPVILTAARNGSGMDELLDTLNDVSFDKYKLNNKPVRYNENIENVVKSIQPELDNIIP
                     GINSRWLGLRLIDGDESIFESMSNYIDKDSIDAINEVKKKIPDNINKQKIRDEFTKIN
                     YDYAKKLSDECCSNVAKKSTDREEKVDKILTSKIFGLPIMLLLLGTILWITIEGANYP
                     STLLSNLLLGFEPSISGILNSINCPSWLNDMLVLGLYRTLAWVISVMLPPMAIFFPLF
                     TLLEDFGYLPRVAFNLDHLFKKACAHGKQCLTMCMGFGCNAAGVIGCRIIDSPRERLI
                     AILTNNFVPCNGRFPTLIAISTIFFSSVITNSFVSSVATALCITLLIILGVIITLLVS
                     YTLSKTLLKGVPSTFTLELPPYRVPQIGRTLYTSIIDRTIFVLGRAVMVAIPAGVITW
                     IFANIYIGDLSILSHVANFLDPLAKLIGLDGFILLAFILGFPANEIVVPILLMAYLAT
                     GSMIELDSFSALGQVLREHGWTYLTALNVMLFSLLHWPCATTLLTIKKETGSLKWTAL
                     GFLMPTILAFVVCFLTTTVYNLFI"
     gene            complement(22780..23598)
                     /locus_tag="OE968_001948"
     CDS             complement(22780..23598)
                     /locus_tag="OE968_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HCP7219228.1"
                     /translation="MEKQYFTTGEFAKLCGISKQTLIFYDKIGIFSPEYKDKNNYRYY
                     SVYQYDTLDILQSLREIGMSLEEIKEYIQNRTPQLCVKMLKEEEKKIREKIKKLRKIS
                     SKMQNRINITVEGISKMNSEEIYISKKFEEYLVLSSDLSNMSNSDFMMELIDFTNYCK
                     SKNLYQGYELGVIVSNENIKNGDYLSISSFYLKIDKKIKDKKLYVKPEGMYACIKHIG
                     KYEDSYKSYEKLKKYIYENEYKIVGNSYEESILDFFCESNEDNYMTEISIQVSR"
     gene            23805..24089
                     /locus_tag="OE968_001949"
     CDS             23805..24089
                     /locus_tag="OE968_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219229.1"
                     /translation="MLVRVKIVIGATIRYLIKHKVNYCNKKSLDKLELKYGNIDREKA
                     VKLEIFYQYLIELEYIEMSLLIRRLDTAITSLALVSIITIASYYLIRKNV"
     repeat_region   24247..25070
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=24314..24342
                     /rpt_unit_seq="atttacattccatatagttaatataaaac"
     gene            complement(25729..27822)
                     /locus_tag="OE968_001950"
     CDS             complement(25729..27822)
                     /locus_tag="OE968_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HCP7219230.1"
                     /translation="MNKHNFEVILNQLQINIYVTNIHTNEIIFMNKKMKEEYNILDPE
                     GKVCWQVLYPEKNSTCSFCKVLELLKNDKKGVLIKWYEKCNKLNRVFENYDSLITWQD
                     GTVVHMHQSIDIANSTSLNKPIKINEFHEISNNKEEKGVFNFSRDNFDYNSTLLYDAL
                     IRGTDEYIYICNMKTGVFRYSPSQVELFDLPGEIVENPLVYWKKIVHPEDWNRFYKSN
                     TEIGKNQMDYHTVEFRAKNRSGEYIWLRCRGQLMRDEFGEPSIFAGIMTQLGKQNKID
                     SLTQLLNYHEFMSVFEDKISNPMIEKLCIVLLDIDDFKNVNEMYDRDFGDNIIKTLAQ
                     SIQSILPDNAELYKLDGDEMGILVDNVEENEILTLYNQIQNMIIHLQLWRKYGLNITI
                     SAGCVIYPKHGDTVKELYKCASYSLQYAKEHGKNRLVFFSQEILKNKMYSLEMMRDLK
                     ASINDDFRGFSLRFQPQVDTESHKIIGVEVLLRWTNDKCKAISPLEFIPILEENDMIN
                     IVGAWVLRMALRTFRKWIDYYPFFKVSVNVSAVQILEDTFIEDIVKIIDDENFPYQNL
                     VLELTESHTVQNMSILQFKFKALQDLGIYIAMDDFGTGYSSLEVLKFSPIDIVKIDRV
                     FVKDILKSKFDATFIHFIVAICHDVGIKVCLEGVETQEEYDLVKQIKPDYIQGYLFGK
                     PQTATEIFDLLKLDN"
BASE COUNT         9811 a         4231 c         3425 g        10421 t
ORIGIN      
        1 ataatataaa cacaggaggt acattctttg aaaaacatta tttcagcaaa agaacttata
       61 tcaaaactag aaaaaaatga taatctagtt gtaatagatt gcagatttga tcttatcaat
      121 agaacttatg gtattgattc ttataaaaaa ggacacatca aaggcagctt tatcttagat
      181 atagacaagg atttatcatc tcctacaaaa gaacatggtg gtaaaaatcc tttacaagac
      241 cctttaatac taaaagaaaa attagaaaaa atgggtgttg ataacgacac tacgattgta
      301 acttatgatg atggagattt aaatggagct tgcagattat ttttccaatt aaaacatttg
      361 gggcttaaaa atgtctatgt actggatggg ggaataacat ctttcgtaaa ggaaggtgga
      421 gaattggaag agaaagtgaa tataccaagt tgtacaggta aggaaattag accaaatata
      481 aacaatggtt tagttgttcc aatggaatat gttaagtcta aattatacaa aaaagatact
      541 gtaataatag attgccgtgc taatgagaga taccagggtt tagttgaacc tgcttactca
      601 aaagctggtc atataccaag tgcaaaaaat tatttttgta aggatttaat aaaaagtgac
      661 tttgaaaatg gctcacttaa agatatagaa tttttaaaaa aattctttaa agatttaaat
      721 aattatgatg aagtaatttt atcttgtggt tcagggatat ctgcttgtgt taacagtctt
      781 gctcttagag aactggatat acctcacaag atttatattg gtagctttag tgactggatt
      841 agttatgatg acaatgaaat caaaactggt caagaataag gctcataatc tatataaaat
      901 cagcatatga tagcttaaat tttgtaaagg cgtcagtcat tgtagacttt cgcctttact
      961 aattatttca tatactcttt aaatttatta tatatatttt agttgataat attaataaac
     1021 tgcaatatga ccatcacatc ttgattccgt cccacaaata taactttcct gttctgtttt
     1081 aaatattatt tgacctcgtc ccatgtcgac agtatcatga attactttta tttcatgacc
     1141 cttttcaatt aatgaatcta ttatgtgctt tggcatctct ggttcaactt ctatttcctt
     1201 tccttttatc cactgccatc ttggagcatc tagcgcctct tgtggattta atccaaaatc
     1261 aatcatattt gttaacactt gaatatgtcc ttgtggttgc ataaaagctc ccattacacc
     1321 aaatggacct attgctttat cttctttacc taaaaatcca ggtattatag tatgataagg
     1381 ttttttaaat ggttttacta cattgtggtg tttagggtct aaattaaaat tatttcctct
     1441 actatgtaaa gcaatcccag ttcttggtat cacaattcct gaaccaaaat ttatgtaatt
     1501 gctctgtata tatgaaacca tatttccatc cttatctgca gtacaaaggt atactgtacc
     1561 accacaatat ggctctcctg cagttggata caaagcctct ttattgtcaa tcaataaact
     1621 tcttttttta gcatactctt ggcttagtaa ttcctgaatc tttaccttca tatgctctat
     1681 atcagttaca tatgttttag aatctgcaaa agctaatttt aaactctcta taattttatg
     1741 tatgtcttct acattttcta tatttccttc taattccaat tcttttaata tgttaagtgc
     1801 cattaaaact gttattccat gaccatttgg tgggatttca aatattttat atcccttata
     1861 ttctgtactt ataggttcta cccatgttgg ataaaaacac tctaagtcac tctttcttat
     1921 agccccatta aattttttag aatattcatc tattttatca gcaagtcttc ctctataaaa
     1981 gctttcagcc tgagtatttg ctatctcttc taatgtactt gcctgttctt cacatataaa
     2041 tatatctcca gcctctggag ctttaccatc tttagaaaat gtatcaaacc atggtttgaa
     2101 ctcttctcca ataagttctt tttcatagag ttcatatgat tttttccata ccttagctac
     2161 attaggagat actacgtatc cctctcttgc atagtttatc gctggagata agcattccat
     2221 taagctaagt ttaccatatt ttttatttaa ttctgaccaa gctgctggta ttccaggtac
     2281 agttactgct ccaaacccat attttggcat ttctttcata ttattataat tttttaattc
     2341 catattttct ggagcaaagc cactagaatt taaaccatac aatcgttttt cttcctctat
     2401 ccaaacaagg gcatatgcat ctcctccaat cccattgctt gtaggttcta ctactgctaa
     2461 tgtggcggct gttgcaactg ctgcatcaac agcatttcca ccctttttta gtatttcaag
     2521 tccagcttga gatgctaatg gtgttgatgt tgcaactgct ccatttttag catacacgac
     2581 atttcttatt gatgagtatt tatgttggta ggcattaaac ttcataaatt tcagctcctc
     2641 gtcatttttt atttgatatt ctgcttagat ttattatata acatcaatta atgtaactga
     2701 tacaaaatga tataaaatat agactttttc ctaactttaa ttttatcttt aaataaatat
     2761 cttaaactca attctagtat tttctatctg cacttaaata agttatttta ttcaaaacat
     2821 atatctaatt cttttaactt aaaaataatt tattctttta tcatgtttag agcatatttt
     2881 aaagttaaaa aataatatat aaaatatcct ataaaataaa tgactagagt tatgataatt
     2941 ggtacaagta atgaccttgg tataaacttt tgtgctatag acatagcaaa taaattatga
     3001 actgtaccta caactaatgg cattaaaaat ataactttta actgttttga tattattttc
     3061 tcaatatctt tattatttgc tccaagtttt attaacataa tatatctttc cttatcatca
     3121 tatatatttg ataattgttt aaataagatt atactacctg tacataaaag aaatactaca
     3181 gacaaaaata tgcctataaa cagcattaga ccacttaatt ttatcaagtt atcataactt
     3241 tcaatacttg atgtaaaatt aaaaggataa gtaaatttca tattttcact tactatattt
     3301 tttaatttta aagtcaaatc cagttctttt ttttcatttt ttatatcaat taatcttatt
     3361 aatctagaat ttccatgtaa ttttaactga ttaaatacgt catcttttac tacaattaaa
     3421 tcaaacgtag cttgtgaatt tatttctggc tccaagatgc ttttttgtac tttaaacaga
     3481 tttatatcat actcatttgc atctttaata tgcaagttta ttttttcaat ctcaaagtct
     3541 ttaaaaaata tttttttgta tgaatcagaa acatagtaca cagattcctt tgaagttaat
     3601 tcttcataat tgttattctg atattgtctt aattttttaa aatcactttc tctaataata
     3661 tctacagacg ttctatcttc tatataacta tttcgatttt tataatacat ttcaatattt
     3721 atatctttgt ctataagttc tattatttta tcaaagatta tcttattatc ttttttatat
     3781 ttatataata atttgtcaat ttcgttattt acataagaat ttcctaaatt tatggtataa
     3841 ctgtatttat aattttcact tatgttccta tctatatcgt aataaagtga tatggtaaac
     3901 cctagcatag ttacacttgt agctattaat attgctatta cagccaatac actactattg
     3961 ctctttaatt taaatccaag ttcagaaaat gcaattaaat tctgtccctt ataataaaaa
     4021 ctttttctct tcttaacagc atcaataatc atatacatag ttgatgaaaa aaataaaaaa
     4081 gttccaggta ttattgtaac taatataaaa actgaaagca taatattttc agcaataaaa
     4141 taactaattg acattaaata agaaatagct attaataaaa caccaagtac acattttaac
     4201 tttataaatt ttttaaactt atacttttct ggatatttat taaataactc tataattctc
     4261 ttatttctga taactatagt atttcttatt ccaataacta tgaatattat taaaaatacc
     4321 gctagtgtct gaactaaggc ctttatactt aagttcatat ttactactat catttcattc
     4381 attaatttta caagcatcat agtcataagc tttgaaaata acagtcctaa aaatatacct
     4441 attagtattg caactatacc catcaaaaaa gtttcatata aaaatatttt tcctatctga
     4501 tttttcctca ttccaagtaa actataagtt cctacttctc gcctacgtct attgaaaaaa
     4561 aatgagtttg aataatatat aaataaaaat acaaatacca ctattacaat tgaacttgta
     4621 ttaatactca tcctagtttt ctctccaagt gaactcaacg cttcattata ctctatagat
     4681 ttaaaactaa aaaatacaaa tacactaaat acaattgaaa taaagtacat taaataatta
     4741 aaaaaactat tctttacatt ttgcattgca attctaaata aagtcatttt tattaactcc
     4801 tccaattaag gaaactgtat ttactatttt attatagaac tctctgttac tttctccctt
     4861 tacaatttct gtgaatatta ttccatcctt tataaagagt attctattgc aaaaactcgc
     4921 acttatagca tcatgagtta ccatcaatat tgttttattg ctgtctttgt ttaattttaa
     4981 tagacaattc aacaaatccc tagcagattt agaatctaat gctcctgtag gctcatctgc
     5041 aagtactaat gatggttttg ttgctatagc tctacataca gctcctcttt gcttttgtcc
     5101 accagaaact tcgccagggt atttatctaa tatagattct atatttaatt cttttgaaat
     5161 ctcttttatt ctattttcta ttactgatac tctttcattt tttaaagaaa gaggcaacat
     5221 tatattttct tttattgtaa gtgtatccaa aagattagaa tcttgaaata caaagcctag
     5281 attatcacgt ctaaaatctg ccaattcatt ttgcttcatt ttaatagtat tctttccatt
     5341 tatataaata tctcctgatg aaggtaaatc tattgtagaa ataatattta aaagtgttga
     5401 tttaccagca ccggaagacc ccataatacc aacaaattct cctttataaa ccttgaaagt
     5461 tattcctctt agagcttcat gttttgaacc ttttcttcca tactcctttt ttatattttc
     5521 aacagataat atttcttcca tagttaataa tcacctttca tcacaattag ttatttatca
     5581 attctcacaa atatattata tatattaaaa tggcttttaa acatttaatt atattaattt
     5641 aaggttacat tttcgtaagt attaattata tttcttcaaa tttattgcaa ttatgtttaa
     5701 aatataattt atcaagtaaa atatagttat attaatataa ttattttagg taataaggta
     5761 gaaatatttt aatttatcaa gtagaatata gttatgttaa tataactatt ttgaattagg
     5821 aggtaagaat gtttaaaata atggtagttg aagatgacgt ctcattgaaa aatatcatag
     5881 caaagtgtct tactaaatgg ggacatgatg ttcatcaaat agaaaatctt gaaaatataa
     5941 tagaagagtt caaaaactat aacccagaat tagttttatt ggacataaac cttccatttt
     6001 atgatggttt tcattggtgt aatgaaataa gaaaaatttc aaaagttcct ataattttta
     6061 tttcttcaag aaattctaat atggatgtaa taatgggtgt aaatttaggt gcagatgatt
     6121 atatacaaaa acctttttct gtagatgtct tagtagctaa agttaatgcc cttttaagaa
     6181 gaacttataa ttttgttgat aataactcaa atcagattat tcacaatggt gttactttag
     6241 atttatcaac tgcaacaata aactatgaag ataatactat tgagctaaca aaaaatgaaa
     6301 tcaaaattct ccatgagctt atgaaatata aggggcagat agtaagtagg aataaactca
     6361 tgaaaaaatt atgggataat gattggtttg tagatgataa tacattaact gtcaatgtaa
     6421 atagaatacg ctcaaaatta aatgaaattg gtttagaaga ttttatagaa acaaaaagag
     6481 gattgggtta tataatcagt taaaacaatt ctaagtaggt gaatttatga gctttaaaga
     6541 ttttctcaag gataaactag gttttttagt atacaatttt actttcttaa tttttacagt
     6601 atcagttatt atattttctc ctgtagatgt ttttctgact gatactattt tatatatatt
     6661 agttgtaaat gttgtgtttt tatttttata tctatttatt agctacatca agaagaacaa
     6721 atttttagat aagataaaaa atgatacatt caaaattaat atgaatgata tagaattagc
     6781 tagatgtaaa aatgaagaaa aaatatactt gaacattatt aaaaatcatc aatatcaatg
     6841 taataacata ataaataata atatcgagaa atttgaagaa aacaaagaga ttttaaatat
     6901 gtgggtacat gatgtaaaga tacctatagc tataataaaa ctcattcttg aacaaaatga
     6961 aaatttaatt gatgaaaaaa tttcagatga catagatagt gaaatattta gaattgaaaa
     7021 ctccgttgaa aaaattttat atttatcaag actcgaagat tttcataagg attttttaat
     7081 tcaagaggta aatattgaaa aaatcattag aaatattata aaaaaatact caaaatattt
     7141 tatttcaaaa aaaattattt tagacttaaa taatttgaat tttaaggttt tatctgatga
     7201 aaaatggcta tacttcatat tcgagcaatt attgagtaat tccctaaaat actcctcatt
     7261 aggagataat atatctatct attgcaaaag aaccaaaaat tatttacaat taagagtgga
     7321 agatactggt tgtggtataa aaaaggaaga tttaaatcga atattcaata agggatttac
     7381 aggtaataat ggaagaaaca attctaaatc tacaggtctt gggctttatt tagtaaaaga
     7441 actttgtgat aagcttggtc ataaaattga tgtagattca gagtacaacc aatatacaaa
     7501 atttactatt acattcaaat gtgatttata gtatcttatt attgatagtt tattttcatt
     7561 aacttatatt caacttctta tagtaattct atatgtacat cccagtatat aattaagtag
     7621 tttttataaa aaggaggaag acatgtcttt tctaaaaaaa tttaaaaata aaagatttag
     7681 aaataacagt tttaaaagta acaactttag aaatagcagt tttggaagta gtggcttcaa
     7741 gtctaaaaat aaaggtttta aaaacaatcc ctttaaaaat aagagattca aaatatatgc
     7801 aggaatagca gtaatcatac ttttaattct aggagttctt gcttatgttg attcgaaaaa
     7861 cactgaatta caagctaatg aaaattttat cgaaacatat actattcctg aaaatgaaaa
     7921 aatatttata aatgggatgg ttgttcctaa gcaaactaag gacttcaata tatctggaga
     7981 ttatgagtta agtgatgtta atgttacaaa tggtcaaaaa gtaaatcaag gagaccttct
     8041 ttttactgct aaaaatccaa ctataatagc agaaatagat agtttaaaat cacaacttag
     8101 tcaatacaaa aaacaaaaaa tatcactttc tgatattgct gaaaataaag atgctattgc
     8161 ttctataaat gcacagataa ctgctttaaa ctctcagata gcttctctgg ataaaaaagc
     8221 ttatgacaga gttactgctc cttttgatgg cacagtatac ttgaatgacc aaactggaaa
     8281 tccagaccaa ccagtttcat ttatgactat tcaaggtcta gagttttata tgaaaggaca
     8341 agcaagtgaa caagatttac ctaaaatgaa gattgaccaa atggtcaata tactagtttt
     8401 ttcaactgac caaaagctta ctggtagaat aagttttata tctgataaac catctactcc
     8461 aaatactgaa atgggagctc agcagaatac actatcttat tatgatataa acatagcatt
     8521 tgataatcaa gaaggattag taaatggatt ccatcttcaa gcatcacttg aagtagctaa
     8581 ttcaagcttt aaaataccag catcttgtgt acttaaagac aacaaacact catatgtatt
     8641 taaggattta gatggtatat tgaaaaagca aattgtagat gtagcaagtc aaaatgatga
     8701 ttttgctgta gttagaggcg gtcttgaaca aggcgatata ataataaaac accctactaa
     8761 agaaatgaaa gaaggagacc cagttcaagg cgatggcgta actgctggtt ctaataatgg
     8821 agatactact ccaaacaaaa aagtagaaga agttactatg gatgtgaatt aatttacata
     8881 tgttaattaa attagaaaat attcaaaaat attacaaagt agggaaagat gaattacatg
     8941 ttttaaaatc cttaaattta gaaattgaat ctggagaatt tgtcatgata atgggtaagt
     9001 ctggtagtgg taaaactact ttacttaata tcttaggttt tctagatgta tttgatgaag
     9061 gaagatatat atttgatgga acagatgtaa ctaatttgag tgaaaatgaa cgttctgttt
     9121 ttagaaatat taatattgga tttgttttcc aacaatttaa tttaatagaa actctaaatg
     9181 tatatcaaaa tgtagagttg cctctaattt acaataaagc actaaaaaaa tctaatagag
     9241 aagaaattgt taaagataaa ttaagttctg ttgggctttt ggacaagctt aagcagaaac
     9301 cacttcaatt atctggtggt caacaacagc gtgtagccat tgcacgttgc ctagcaaatg
     9361 accctcagat aatctttgct gacgaaccga ctggggcatt agatagtgaa actagcagag
     9421 aaattatgga gcttttaaca aggctcaaca aacaaggtaa gactataata atggttacac
     9481 atgatcaaga tttaactaag tatgcaacta aggttatacg acttaaagat ggtgtgttta
     9541 cttcggaggt gtaatcatga gtttattaaa aaattctttg gccaatttaa aaggtcacaa
     9601 gcttcgtgta tttgtagctt tactctggat tataatagga ataacttcag taatacttgt
     9661 tagttctata ggtaatggat ttcaaaaaga aattaagaaa tctgtaaaca atgtaaaccc
     9721 taataaaact actatttcgt ttgaatcagc cgataacaca ggtcttactg atgatatgag
     9781 tattttttta aaacccttta atgcaaaaga tttagaagaa ttatcatttg ttgaaggagt
     9841 agaaagaata gctccttcaa gagatgggtt taaccttgat tcagtttact cttcacaagc
     9901 atcttttgat aaaaaaacta cgtatgttga tgttggacca gtaaaaaaag attctaaaat
     9961 aaatttaatt tgtggtagag atttttcttt agatgatgaa aaaagaaaag taattttact
    10021 tacattacaa agtacaagtg aaatttttga aaatccagaa gatgccttag gtcatggtat
    10081 caacataaat ggaactatat ttgaaataat aggggtatta gatgattctc agcaaaacca
    10141 agctggagga ttctttggag gttaccaaga tatgcaattt actacttccc tagtacctaa
    10201 aaaggctttt gacactttaa tgagtcaaaa ttcttattca aatgaaattt accagttaga
    10261 cttagtttct tctaaaggct ataatgtaaa tgaagttgca aacaatgtta tagctaaatt
    10321 atatgagatg caccctggta tcaatggttc ttatactaca ccagacccaa ctgaacagac
    10381 agcttatctt gaaagcatta attccaatgt aaacaaatat gtatctataa taactgtagt
    10441 tgcaatgttt gttggtggta ttggtgtaat gaatataatg tatgtatctg ttatggaaag
    10501 acaaagagaa attggtataa gacgtgctat tggagcaaaa cctaggtcta tattatttca
    10561 atttttagtt gaagctgttt ttataacagt atgtggtgga attttaggaa ctatagttgg
    10621 atttgctgct actaactatg tttctaaata tataggtttt gaagctatac ctagcttaaa
    10681 tagcttattt tatgcaattg tagctactat attgactgga gttgtatttg gtctgattcc
    10741 agcctttaaa gcttctaaac tagaccctat aaaggcaatt tataagtaga aattgtataa
    10801 agattttcga tttttagatt agtttatata aaacatactt aaatatataa cgcactatta
    10861 tatatgatag attaggaact taatctttcc aaatataata gtgcgttctt tcataaaaag
    10921 gattctcttc cttactatat ctaaattacc aagatgttat gttctaattg ttcaaactaa
    10981 tacttccaat tttgattaat caatctcatt ctcctaatat acaatctttt actttcaatc
    11041 attgtacact ccgccttaaa aaaataatct taaattaggc gttatataca atctccccat
    11101 tacatattgt ataattaacc tttccatata aagatttacc tttaaatggt gaattatcag
    11161 ctttagaaac aaagctttca actgtccatt cttcttctgg attgaatata acaatgtctg
    11221 ctacagcccc ttcttctata aatccaatat ttaaattgta caattttgca ggatttatag
    11281 acattttttc tattaactgc atcatactaa gatgattttt atgcaccaaa tttgttattc
    11341 caagagctaa agaagtttca agcccaataa ttccacttgg agcttttata aactctctat
    11401 ctttttcttc tttactatga ggtgcatggt ctgttgctat tatttcaata gtaccatcat
    11461 ttaatccctc tataatctta tctctgtccc atttacttct tagaggtgga ttcatttttg
    11521 catttgttcc aaactccaat acatcttcct cagtcaatgt aaagtgatgt ggtgaagctt
    11581 ctgcaactac atttgcacct aagtattttg caaatctaac catatcaaca gatacacctg
    11641 aacttatatg ttgtatatca actttagcac cagtctttag tgccaacata caatctctgg
    11701 ctaccataac atcttctgct acacttgatg caccttttaa tccaagttct gaagctacct
    11761 ttcctgcatt tacacctgga tttccaacta aagaagggtc ttcttcatga aaactaagtg
    11821 gtacatccaa ctcttttgcc ttaatcattg cctccataat tagattgcta tccattaaag
    11881 gtaatccatc atcagtaaac cctggtacac cagctttttt aagagcttcc atatcaacta
    11941 actctttacc ttcaaaacct ttagttatag ctgctgcttg taaaacattt atacatgcat
    12001 tttttgactt ttctttaaca taattaaaag tatcttcatt atctacaata ggattagtat
    12061 ttgccataca tataacagtt gtaaatccac ctctagcagc agatttagct ccactttcta
    12121 tatcttcttt atatgtaaac ccagggtctc taaagtgtac atgtacatcc actaaacctg
    12181 gagcaactac attaccacta gcatctatta ttttttcata ttcatcactt tcatcaaact
    12241 tgcctatttt ataaatttta ttttctttta taattaagtc aatattctca tctctttgac
    12301 ttttagggtc tattactcta ccatttttaa ttaaaatcat attatttctc ctttatattt
    12361 ttaatttata tagactcata taatattata cattatttta catacttaaa tacaaaatta
    12421 cgtttgacat caatagcctt tttaggacaa agttcatggc aacagtaaca tcttatacat
    12481 ttacttaagt ctataatagc acccttagtc cctatctcta tagtggatgc aggacaagct
    12541 tccttgcatt ttccacattt tatgcaatct tgaaatctta ccacaggctt tggtgttata
    12601 agctttgaaa taggttcatt taaaaatttt ggtagcttta cggaaaacaa tcttaaatct
    12661 ttacttacat ttggaatctt gtaatttttt ataattaaat cttttatatc ttcacctaaa
    12721 atttcaatat ctgaaaaatc ttcttgtata tatcctctct taatagcacc tctaattgta
    12781 gcaactttat ttggaagtaa acttataatc ttacatgcaa caacatctat agcatatgga
    12841 ttttgtgatg ctaataaaac tcctatttct cgagtagtac cagctgaagg tccatcacct
    12901 tccataccta ctataccatc cataattgtc aatgttggtt ttatataatc acaaatatct
    12961 aaaagtacat tttcgcaaaa caactcttct gtaggaaatc tataatgtat ctctgctttt
    13021 ttcaatccag ctatgcatcc atataagttt tttgtaccac cagtaaaagt tgccattata
    13081 tgagtcttta atttacaaag atttattata taatctgaat ctactattgg tttaataata
    13141 tccatatatt ttagaacatg tgctttttca ctatgtatct taacatctga aacatcataa
    13201 tttaacttaa tgcccagttc atttgctact tcttcaattc cagatgcctt ataaatgctc
    13261 ttaagagaac tttgattata tggaccacca gggctatctg ctattgtaat atcacaattt
    13321 aactctaaaa gtttttcaca tacaactttt acaaccatag gatgtgtagt tgtagcttct
    13381 tcaggctttt ttttcattaa taaatttggt tttataagta ctttgcttcc ttttttaaca
    13441 aacttatcta taccaccaat atcctctaaa tttttttcaa tagataactt tacttcttca
    13501 taattgtaag ttttacaact cctaacagat accgacttca tattatctcc atccttctat
    13561 cacaacagtt tatttatata atttaaaaaa ggagaaacca aagtttctcc ttttaatcta
    13621 tgttttaatt gttttaatta ttattttcca aaatgtctgt ttaataatcc taagaatgct
    13681 ttaccatgtc tagcttcgtc tttacacatt tcatgtactg tatcatgtat agcatctaat
    13741 cctaattctt tagctctctt agctaatttt aattttccat cagttgcacc atactcagca
    13801 tcaactctaa ctcttaagtt ttcttttgta tctgcaacta caacttctcc aagaagttct
    13861 gcaaatttag cagcatgttc agcctcttca aaagctattc tcttatacgc ttcagctact
    13921 tctggataac cttctctatc agcttgtcta ctcattgcta aatacattcc tacttctgta
    13981 cactcaccag taaagttagc tcttaatcct tcgattattt ctgcatctac accttgagct
    14041 actcctattc tatgttcatc agcccaaacc atttcgcctt tcatttcttc aaatttatca
    14101 gctccaactt tacatactgg acattgtgct ggtgcagcat ctccttcatg tatatatcca
    14161 catactgtac aaacaaattt tttcataatt aatttcctcc caattttata taattaaatt
    14221 tttattttta agtttaataa cttgctacaa gaatatatat accccagact ttatagctta
    14281 aacactaaaa ataaaattta tttcctaatt aattttatca ctttgaaaca ccagtatcaa
    14341 ccaagttttg atgtcaaatt tctacataat acataattta tttgattaat taggaaatag
    14401 ttgtcatatt aaatactttc taatgaagac tcctctgaat ctttaagttt cacttttttg
    14461 ctctttaaaa aagataattt agtttctgca gttatgattg caacaaatat caagatacta
    14521 ccaataacca attttgctgt aataagctcc tttaaaatta ttatagaaaa tattgtacca
    14581 aatacagcct ctgtggataa tattatagct gttctagttc catcaactct tttttgacat
    14641 atagtctgaa ataaaaatcc aattgtagta ctaaatacag ctagatacat agttcccatg
    14701 taaccagata attcagcttc catctttaat tgacctgcaa atgtttgaac tacaacagac
    14761 attaaaaacg ctactgtaaa ttgaatagct gtcaatgcca ttgggttgtt atcttttgca
    14821 aactcacttg taaagaatat atgaaatgca aatccgaatg aacatataag tgttagaaaa
    14881 tctccaaaat taatagagaa atcagcttct aaagaaagta tcccaattcc tataagagct
    14941 accaaactac ttattattcc tattttatca agttttcttc tataaagtat aaatcctatg
    15001 aatggaacta ttacaacatt agctgctgtt ataaacgcat ttttagatgg tgtagtgtac
    15061 ataagtccaa tagtttgtac tgtgaatgct agaaataaaa atattcctaa aatccctcct
    15121 gcttttaata attttttacc catattggca cgaatctgtt taaaaaacag taaattcata
    15181 attatagctg ccaagaaaaa tcttaaagtt atgatttgta gaggtgtaag cccaccgtct
    15241 aatgcaaatt gggttgctac aaagccactt ccccatataa ttgctataaa tattagtcct
    15301 atttctccaa agtatttttt caataaagct ccctcctttt tatttttttg caaaattata
    15361 aaccccctaa acagcaagag agtttttcta taagcattac tataaattaa tatagtaaat
    15421 tttttcagta ttttaaatct aaatttacat acattttgag ctcaaattta tatccactat
    15481 ttaacagtaa tatattaatc attttttgta aacacctttt taataaattt ttatattttt
    15541 tatatttttt tacctatact aaattttttt atagatattt ttaatatata tgatacttta
    15601 atattatgca aataatgtca tataagttac actttagtta tcttagttac aactttgtcg
    15661 gtttactttt tctactttct tcgatataat tataatatat ttttgataca attcgacaaa
    15721 agggggaatg ctgtaattat ggtaaaaaaa agaaaaaaga aaactgttac acttactata
    15781 cttgttgtaa tagttattgg tattttttct atggcatggg cggacatgtc tagaaaaaaa
    15841 gaaatgaaag aaactcaaga aagacttaaa gctgaaagat tagaaaaaga aagaattgaa
    15901 aaagaaaaaa atgaacctat tattggtgca aaaaaagaag ctgtaaaaga atatggatat
    15961 gacgcaaaaa tagtttggga caaacttaac aaatacgact attcaaacaa tggagaaaag
    16021 atagtctttc ttacatttga tgatggacca tctactacta atactccaca agttctagat
    16081 atcttgaaaa gacatggtgt tagaggaact ttctttatta agggtgattc tcttgaaaga
    16141 aaaggagcta atgaaatttt aaaaagaaca tttgacgaag gaaatgcaat agcccatcac
    16201 tcttatactc atgactataa aaaactatat cctaacagaa gcctaaatct cgatacattc
    16261 gtaaatgaac ttaacaaaac tgatgaagct atgaaaaaag tcttaggaaa gaatttttcc
    16321 tcaaatgtag ttagatgccc aggcgggtac atgtcatgga aaaatatgga acctctagga
    16381 aactacttaa aagagaaaaa catggcatca attgattgga acgctttaaa tgctgatgca
    16441 gaaggtaaaa agaaaaatgc acaagaatta tttgaacatg caaagaaatc ttctgaaggc
    16501 aaagaaatgg ttgttctttt aatgcatgat acttatggaa aacaagaaac agtaaatgca
    16561 ttggaccaaa ttataacata ttttaaagac aatggttatc aatttaaaat tttaatataa
    16621 taaaaaagca agtttattga atgtacattt tatactcaat agacttgctt ttactttact
    16681 ctattttact agctcgattt ttacaaattt tttctttcct atttgaacaa ctaattcact
    16741 ctcttttaca atagtgctta aatcctctac tttttcacca tttaccttta ctccaccttg
    16801 agaagctaat cttctaactt cactcttact cttaacaatc tcattagaaa ctagtacttc
    16861 gattaagtca aatccatctt ccttaacttg aattgtttgt atatcttcag gtatttgacc
    16921 tttttggaat acagatttaa atctttcttc agcttcttta gcagattctt ctccatggta
    16981 taatgttact atttctcttg ctaagttcat ctttatatct cttggattta ctgaaccctc
    17041 tttcaactga gattctattt tattaacttc atcaggatga acatctgtca ctaaattgta
    17101 gtatttaatt ataagttcat caggaatttc catagatttt tggtacatta ttcccgcttc
    17161 ttcatctatt ccaatatagt tacctaaact cttactcatt ttttctttac catctaatcc
    17221 ttctattaaa ggcatcatta ttactatttg agactccata ccaaattctc tttgtaatga
    17281 tcttcccatt agtaaattga atctttggtc agttccacca agttctatat cagcttctaa
    17341 tgctatagag tcatatgctt gcattaatgg gtagaagaac tcatgtactg atattggcat
    17401 ttgtccttca tatctctttt taaaatcttc tctttctaac attctcgcaa cagtaatagt
    17461 tgctgctaat tttattacat cttcaaaatt taacttagct aaccactcgc tattaaatct
    17521 tacaatagtt ttttctttat ctaaaacttt gaaaatttgt tcttcataag tttttgcatt
    17581 tgcaagaact tgctctgttg ttaaagcttt tctagcttta gattttccag ttgggtctcc
    17641 aatttttcct gtaaaatctc caattattat tactatttga tgacctaaat cttgtaattg
    17701 tttcatcttt ctaagaacta ctgtatgccc taaatgtata tctggagcac ttgggtctag
    17761 acccaatttt actatcatag gctttccttc tttttctgat ttaataagct tttcccttaa
    17821 ctctttctca tctattaaat catctacacc tttcataatt attcgcattt gctcgtctat
    17881 cgatttcatt tttcattcct cctaaaatat ttatataatc tataattttt atttttataa
    17941 taaaaaaagc tttcatcctc ttaaaaggac gaaagcattg cttacgtgtt accaccttag
    18001 ttcatcaata tctcacgata ttaatctctt agagtacaat tacatatact cgtgtactat
    18061 aacgtgtact aatccgatat ctcttaatgg ttgttatctt tcagagatag tgctctgaga
    18121 tgtattcaaa ctaaatcaat ttattccatt tcaccaaact ggaactctct gttaaataaa
    18181 atctagccct acttcttctc ttcatagcat ttatatattc agattatttc atcaattaca
    18241 agaaattttt cttaacttac tcataatata ttattatttt tatattttgt caaccttttt
    18301 tattattata tacatgtttt tttacattat actacttttt tatatttttt accaataccc
    18361 aaaatttatt tttcaatcaa aagatttatt tgtttattga ctatattact ctgactcaat
    18421 cttatattta ttttcttatt taaaaatgcg tttataatta ttaaactaat aactgttaca
    18481 tcaaatataa aaaacagcaa taaaattatt atcaaaaata aaattctagc atataataat
    18541 tttctaaact tagctattat aaagttttgt agtgacatac atgagtctct aatgataaaa
    18601 tagacactta tataggttat tgatataaag attgttttta aataaacaga atcaacttta
    18661 acattcaaca gttttagaac ttcaaaaatg gctagataag aaacacatat gtaaaaagct
    18721 ttttttgagc aacataaaaa ttggtttaaa tttctaaagt tcttaaatat taaaaatttt
    18781 tttaaagaat tagaatctaa aatatgcaat ttattcccta aaattaaact taataaatat
    18841 atgcaaaaca ccataccaaa aggaaacaat gctatcatta aataataaat aaaatttgta
    18901 tacccattaa aataaatcca tttgctatat ccttgaaatt ctttcataaa actataacct
    18961 attaatgttg aagcatatat atcaatgaaa accattacaa taaccccaaa tactgaacca
    19021 tatactaaat catccataac cattgtaggc ttatttatta gatagccaca cattatacca
    19081 agtaatacac tctgacttgc ccaaatagca gttcctagat ttccaagtac cagagaaatt
    19141 attaaaagcg aagtaattcc agataaaatg gtatacttta aatcacattt caagcagatt
    19201 atacaaaaaa atactggcac tataaaatct aagtaaatag catatccaaa tccagtactc
    19261 acagctataa ttgttactac tatgaataaa gatgacaata aagctgcttc agttaatttt
    19321 ttagtagtat tcaaaacact gcctccataa atcataaatt ttctaactaa agttttgttt
    19381 ttaatatagt atatcacttt ttaaaaatat ttttaataaa tataaatttt aataaaggta
    19441 tttatgttaa aaatggtata atgtatctta atattcagtt ttttaagatg ctaggaggta
    19501 attactatgt ttaaaattaa acactttaat gatttgagtt tagatgaatt ttatgaaata
    19561 gcaaaatcaa gatatgaggt atttgcttgt gaacagaaga tattttcatt aaacgattat
    19621 gatgatatag ataaaagctc ttatcacata tttttaaaag aaaatggatt gatttgtgct
    19681 tacgctagaa taattcctaa agaatacagc tcttataatg atgtttccat tggtagagtt
    19741 ttagttcttt ctagtcatag aagaaaagga ttagcaaaac aaatgatgga ttgtgctata
    19801 gattttataa aagttaactt acacgaaaat aatataacct tatcagcaca aacttatata
    19861 aagaaccttt acttatcttg tggttttaaa gaaatctcag aagtatacga cgaagcaggt
    19921 attgaacata ttaaaatgag attatagtgt tgacaagcta atattgttaa tatataattt
    19981 aagtataaat taaatattga attgatattt aggtatttga aaatacctta catagagtca
    20041 gaaggctttt gctttctgac ttttttatta tcaaaattca ataattatat ggattcaaag
    20101 tgttaatttt tattctatat tctactttcc ccaaaagtaa gaattatacc caactttgta
    20161 tgataggcat cttgcctatc ttttttttgt aaaagtaaca aggtaataat ataatgcata
    20221 gtttaaaata agaagattag cccaggctaa atttcaagca tggaggtgct attatgaaaa
    20281 accttaacga tattcaagtg aaaaaaactg tcaaagttga agatatatta tctagtggta
    20341 atttaagaga aagaatgtta gcgcttggtc ttactagagg agctgttata gatgtagtta
    20401 gaaaaggtcc aaaaaataat ttaactgtct ataaaatcag aggtagcaag atagctctac
    20461 gacaagaaga aagtagctta atattagttt ctgacattta aaaatttcta gcaggaggat
    20521 attaatatgg ggttgacaca taactcaact aaaatgagtt ctttaaaaga catgtttgat
    20581 atagacaata aggaagacca gtttgtaatt gcattggctg gcaatccaaa tacaggtaaa
    20641 agtactgtat ttaatcatct tacaggactt agacagcata ctggaaactg gccaggaaaa
    20701 actgtagcta cagctcgtgg taattttaaa tataaaaata ccgaatatgc attaatagat
    20761 ttaccaggaa catattcttt atttgcctta tcacaagaag aaattgtagc tcgtgatttt
    20821 atatgttttg gtaatccaga tgcagtaata gtagtatgtg atgctacatg tcttgaaaga
    20881 aatttaaatt tagtatttca agtgatggaa cttacagata aagttatttt gtgtattaat
    20941 ttaatagatg aagctagaaa aaaaggcatt actattgata aaaaactttt agaggattct
    21001 cttggtattc cagttatttt aactgctgca agaaatggct ctggtatgga tgaactattg
    21061 gatactttaa atgatgtatc ttttgacaaa tataaattaa ataataaacc tgttagatac
    21121 aatgaaaata tagagaatgt ggtaaaatca attcaaccag aattggataa tattatacca
    21181 ggtataaatt ctagatggtt gggacttaga cttattgatg gcgatgaaag tatatttgaa
    21241 tctatgagta attatataga caaagattct atagatgcta ttaatgaagt aaagaaaaag
    21301 attccagaca atataaataa acagaaaata agagatgagt ttactaaaat caactatgat
    21361 tatgctaaaa aactgagtga tgagtgttgt tctaatgttg ctaaaaaatc aactgataga
    21421 gaagaaaaag tagataaaat attaacatct aaaatatttg ggcttccaat aatgctctta
    21481 ttattaggta ctatattgtg gattactata gaaggagcta actatccatc cactttatta
    21541 tctaatttat tactcggatt tgagccaagt atttcgggta tattaaatag tattaattgt
    21601 ccatcatggt taaatgatat gttggtttta ggattataca gaacattagc atgggtaatc
    21661 tctgtaatgc tacctcctat ggcaatattt tttccattat ttaccctact tgaggatttt
    21721 ggatatttgc caagagttgc atttaactta gaccacctat ttaaaaaagc ttgtgcacat
    21781 ggaaaacagt gtttgactat gtgtatggga tttggatgta atgcagctgg agttattggt
    21841 tgtaggataa ttgactctcc aagggaaaga cttatagcta tacttacaaa caactttgtt
    21901 ccttgtaatg gtcgttttcc tactttgata gctatatcta caatattttt tagctcagtt
    21961 ataaccaact ctttcgtatc aagcgtagca actgcacttt gcataacttt actgataatt
    22021 ctaggtgtta taataacatt gttggtttct tatactcttt ctaaaacgct attaaaagga
    22081 gttccgtcta catttacatt agaacttcct ccttatagag ttcctcaaat aggaagaact
    22141 ttatatacct ctataataga tagaacaata tttgttttag gaagggctgt aatggtagcc
    22201 atacctgctg gtgtcataac ttggatattt gcaaatatat atataggaga tttaagtata
    22261 ttatcacatg ttgcaaactt tttagaccct ttagctaaat taattggtct tgatggtttt
    22321 atattacttg cttttattct tggattccca gcaaatgaga tagttgtacc tatactttta
    22381 atggcttacc tagcaactgg ttctatgata gaattagata gctttagtgc tttaggtcaa
    22441 gttcttagag aacatggatg gacttatttg acagctttaa atgttatgct gttcagttta
    22501 ctgcattggc cttgtgcaac aacactttta acaataaaaa aagaaactgg tagtttaaaa
    22561 tggactgcct taggattctt aatgcctact atacttgctt ttgttgtttg ttttttaaca
    22621 actacagttt acaatttatt tatataatta gtattaactg acagtagaca tatattagag
    22681 aaaccattta aaaatttata tactttatta taaagcatag agatatattc aatgataagt
    22741 aaaattactt aacatttgaa tatatctcta ttttaattct tatctggata cttggattga
    22801 aatttcagtc atataattat cttcattact ttcacaaaaa aagtcaagta tactctcctc
    22861 atacgaattt ccaacaattt tatattcatt ttcatatata tattttttca atttttcgta
    22921 agatttatat gaatcctcat attttccaat atgttttatg caagcataca ttccttctgg
    22981 ctttacatat agctttttat cctttatttt tttatctatc ttcaaataaa aacttgatat
    23041 acttaaatag tccccatttt ttatattttc attacttact attactccca actcatatcc
    23101 ttgatacaaa tttttcgatt tacaataatt ggtaaaatct attaattcca tcataaaatc
    23161 actattactc atattactca aatcgcttga tagaactaaa tattcttcaa actttttgga
    23221 tatataaatt tcttcactat tcattttaga aattccttca actgttatat ttattctatt
    23281 ttgcatctta gaacttatct ttcttagttt ttttattttt tctcttatct ttttttcttc
    23341 ttctttaagc attttcacac aaagctgggg agttctattt tgtatatact cttttatttc
    23401 ctctaaactc attcctattt ctcttaatga ttgtaatata tcaagtgtat catattgata
    23461 aactgagtaa tatctataat tatttttatc tttatattca ggagaaaaaa tacctatttt
    23521 gtcatagaaa attaatgtct gcttagatat accacacaat ttagcaaatt cacctgttgt
    23581 aaaatactgt ttttccaagg gttatacact ccttttcttt ttgttgtcta tatagttact
    23641 atattcttta ttatttacta aatcaagtag ttattatttt agaaaatcaa tatggttttg
    23701 attttaaagc ttaaatatca gttagatgtc agttataaat attttaccca ttcccatcat
    23761 aaaaaagata tcccctctta acttttggat ggaatattat atttatactt gttagagtga
    23821 aaattgtaat aggtgctaca ataagatatt taattaaaca taaagttaat tattgtaata
    23881 aaaaatcttt agataaatta gagttaaagt atggaaatat agatagagaa aaagctgtta
    23941 aactagaaat attttatcaa tatttaatag aacttgaata tatagaaatg agtttattaa
    24001 taagaagatt agatactgca ataacatcat tagcattagt atctattata acaatagcat
    24061 catattattt aatcagaaaa aatgtgtaat tatgtaagct atttataata aaacactgat
    24121 aaaattaata ataaaaagat aataggattt ctatactacc tttttgtttt tataatatag
    24181 tgtaatttta ttatattttt gtatgctaat ataactagat aatcataaga taacacatta
    24241 aaagaaaatt atattctgta tagttagtat aaaacgtaag taatataaat ttatgtaaag
    24301 caacaaaaga tggatttaca ttccatatag ttaatataaa acgatttcaa atgattagaa
    24361 taaaaatatc agaattgcta tttatattcc atatagttaa tataaaacta taaagtgtta
    24421 cttttattta ttttattttt tacataattt acattccata tagttaatat aaaacgcatt
    24481 atatggctgt gtcattttgc attctattac atatttacat tccatatagt taatataaaa
    24541 cctgcttaat gcagaattaa gagaggaagt gttataagat ttacattcca tatagttaat
    24601 ataaaactgg ttgttcctgc tccggtgttg gtggaactgg tacatttaca ttccatatag
    24661 ttaatataaa acgaatatgt atggataatt ttttacttaa catattagca tttacattcc
    24721 atatagttaa tataaaacct gctgtaattt ctgatgaagc ttctccacta ccaccattta
    24781 cattccatat agttaatata aaacccttct ttaactctta tcgtatttaa acctcttata
    24841 acatttacat tccatatagt taatataaaa ctttttgtgt taagaagaaa aaagaaattt
    24901 tgataatatt tacattccat atagttaata taaaacctta aagaaaaaat ggaggaagat
    24961 taagtgaaaa aattatttac attccatata gttaatataa aactggattt aaataatcaa
    25021 aacaactccg gtttaaaaaa catttacatt ccatatagtt aatataaaac cccaaaataa
    25081 acttagtatt ttcaacactt acacgtatac aactctctta aatttgcagt gaacgagcaa
    25141 tagtgcaatt gataacgctt atcatacact ctcaacgcct tatatttcaa ctgttacgcc
    25201 aaattttttc acaaatatcg ctcactgcaa aattcctata attttattat atcataaata
    25261 tattactttt gaatattgat accaatttat accataataa aagcaaaaaa acgtaatcta
    25321 tctacattag atttaaattc tataacttaa agttttttac ataatattta tgcttgttta
    25381 atcaatctaa tatatcattc ttgtatattg cttttaatag tcttttttct taaataaata
    25441 tctatctgaa caagcatagt ttaattaaaa acttttgtat tcccttaaaa ctgtatctac
    25501 ctcttattat tttatttatg atatattatt tttaatctaa aaatagatat ctatttttat
    25561 tatggttatc cctttttaaa atactttaat catatactat tcccaattta acatccattg
    25621 aaatgctatt ttcttatatt gcaatttata attgatatat cttcaatata ataatttaat
    25681 gtatttttga ttttaaagct tttcagtgat attattgata aattagaatt aattatctag
    25741 ctttaaaagg tcaaagattt ctgttgctgt ctgcggtttt ccaaataaat atccttgtat
    25801 gtaatctggc tttatttgtt taactaaatc atactcttct tgtgtttcta caccttctaa
    25861 acatactttt attcctacat catgacaaat tgcaacaata aaatgtataa atgtagcatc
    25921 aaacttactc tttaatatat ctttaacaaa tactctatca attttcacta tatctattgg
    25981 agaaaatttt aaaacttcta gagacgagta tccagtacca aaatcatcca tagcaatata
    26041 aattcctaaa tcttgtaaag ccttaaattt aaactgtaaa atactcatat tttgtactgt
    26101 atgactttct gtcaattcta aaacaagatt ttgataagga aaattttcat catctataat
    26161 ttttactata tcttcaataa atgtgtcttc taatatttga acagctgaaa cgtttacact
    26221 cactttaaaa aaaggatagt aatcaatcca tttcctaaaa gtacgtaatg ccattcgaag
    26281 cacccaagcc cctacaatat ttatcatatc attttcttct aatattggaa taaattccaa
    26341 aggagaaatt gctttgcatt tgtcattagt ccaccttaaa agaacttcta cacctattat
    26401 tttatgactt tctgtatcta cttgtggctg gaatcgaaga ctaaaccccc taaaatcatc
    26461 attaattgat gcctttaaat cccgcatcat ttctaatgaa tacattttat tttttaatat
    26521 ttcttgggag aaaaaaacaa gcctgttttt accatgctct ttcgcatatt gtaaagagta
    26581 actagcacac ttataaagtt cttttactgt atctccatgt tttggatata ttacacaacc
    26641 agcagaaatt gttatattta atccatattt tctccatagt tgaaggtgta taatcatatt
    26701 ctgtatttga ttatatagag ttagaatttc attttcttca acattatcaa caagaatgcc
    26761 catttcgtcc ccatcaagtt tataaagttc agcattatct ggtaaaatag attgtataga
    26821 ctgtgctagt gtttttatta tattatctcc aaaatcccta tcatacatct cattaacatt
    26881 tttaaaatcg tcaatatcta ataatactat gcataatttt tcaatcatag gatttgaaat
    26941 tttatcttca aatacactca taaattcatg ataattcagt aactgtgtca atgaatcaat
    27001 cttattttgt ttacctaatt gcgtcattat tcctgcaaaa atacttggtt ctccaaattc
    27061 atcacgcatt agttgacctc tacatcttaa ccatatatat tctccactac gatttttagc
    27121 cctaaattcc actgtatgat aatccatctg gtttttacct atttcagtgt ttgacttata
    27181 aaaacgattc cagtcttctg gatgtacaat ttttttccag taaacaagcg gattttcaac
    27241 aatttctcct ggtaagtcaa ataattcaac ttgtgatggt gaatatcgaa atacgcctgt
    27301 tttcatattg caaatgtata tatattcatc tgtacctcta atcaaagcat cataaagcaa
    27361 tgtagaatta taatcaaaat tgtctcttga aaaattaaaa actccttttt cttctttatt
    27421 atttgatatt tcatgaaatt cattaatctt aattggttta tttaagcttg ttgagtttgc
    27481 aatatctatt gattgatgca tatgaacaac tgtgccatct tgccatgtaa ttaaactatc
    27541 ataattttca aaaacacgat ttaacttatt acatttttca taccacttta ttaatactcc
    27601 ttttttatca ttctttaata attctaaaac tttacaaaaa ctacaagtag aatttttttc
    27661 aggatataat acttgccaac aaacttttcc ttctggatct aaaatattat attcttcttt
    27721 catttttttg ttcataaaaa taatttcatt agtatgaata tttgtaacat atatattaat
    27781 ctgtagttga tttaatataa cttcaaaatt atgtttgttc atatacttat ctcctccata
    27841 gttactgctc tttataacaa cattgttaaa attattcttt ttagaaga
//
LOCUS       DAJMZY010000046        27565 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.046, whole genome shotgun sequence.
ACCESSION   DAJMZY010000046 DAJMZY010000000
VERSION     DAJMZY010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 27565)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27565)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27565
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.046"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            187..861
                     /gene="fsa"
                     /locus_tag="OE968_001951"
     CDS             187..861
                     /gene="fsa"
                     /locus_tag="OE968_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HCP7219231.1"
                     /translation="MQLILDTGNVEEIKELCTCLPIDGVTTNPSIVSKEKKNFKQLIN
                     EIGEIIGEDMPIHAQVLSTKYEEILEEALYISSLRKNIYVKIPVTQDGLRAIKDLHRK
                     GVKITATAIFTAHQGFLAAKAGANYIAPYVNRLDNISGDGVAMVSELIKIIDTYKMDT
                     KVLAASFKNAQQVIELMQHGVHSVTVPYDICKSMMNHPLTDWSVDKFIEDWENTFGKG
                     SKTNNI"
     gene            complement(983..2377)
                     /locus_tag="OE968_001952"
     CDS             complement(983..2377)
                     /locus_tag="OE968_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HCP7219232.1"
                     /translation="MGIILKPKQFYMTVIATIILYFSLNYSFNIKFSICLSFLTILIW
                     AVDSVEKTFVALFFVILAFIFNIAPIKVILQFLFTENFYIIILAYIITNAVTKTGVAK
                     IISEKLILNTVNTPKKMILLSYILGILLIFFIPQPFPRVILVSAFYKEFLKEQQITED
                     SKSILLFSIFTASTFTSMFFVNGDTLLNYVVLELGNCNINWGQWAFYMSVPTIITCFI
                     TYFLFTFVFKKELHSIKFISNENLEGNKLHFSYSNLKKEFNLLNKEQKHVFLCLGIMF
                     FMFLTQFIHNINTLIIMSICVLLLLLRKIVGFSTLKEINWKVLIFFIAAFSIGGVLKY
                     SGVVDIMGNYLIKFIPNSSEIISILFLITLTIILNICLGSAVTTSSVVIPLLGSLHIL
                     KENSVTLCLFVYIIVSIQYILPFHHATIMVGHGENLYNSKVIFKYGLTLIPLTYFIII
                     CITFPWWKFIGLEI"
     gene            complement(2455..3801)
                     /locus_tag="OE968_001953"
     CDS             complement(2455..3801)
                     /locus_tag="OE968_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HCP7219233.1"
                     /translation="MKDLTTGHEGKSIFFFAMPMLIGSLFQQLYNTADSIIVGRFIGK
                     EAMAAVSGANPIMFLLVAALMGVSLGFSILVSQFYGSGDLKKVKATIDTTYILLFIGS
                     ILISILGIVFGGPMLKLMNTPESVFAQSKLYLTIIFSGILFSAGYNSVSAILRGLGDS
                     VTPLYFLIIATILNIVLDLTFIVVLRMGVEGVALATIMAQAVSFIISIIYLNKKHEVL
                     KFKIKGIVYDNKIFKDGLRLGLPSGVQQMLFSIGNMALQFLVNSYGTSAMAAFGAGLR
                     IENFISLPIMNLGSAVSTFVAQNIGAGENERVKKGIRESIKMTLVLAVTVIALILLFR
                     ENLIALFNTDKDVIKIGSSYLFIIGPFFLFIGTSFVLSSAMKGAGDSMFALISSIVSL
                     WLGRLPASYMLSKFFGTDGIWMGIPFGWTLGLIVTVIYYKKGHWKTKAIVNHRINE"
     regulatory      4051..4153
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            4247..5623
                     /locus_tag="OE968_001954"
     CDS             4247..5623
                     /locus_tag="OE968_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HCP7219234.1"
                     /translation="MQTTNSSTMQKLFPILTNKNVDMKKEIIAGVTTFLTMAYIIAVN
                     PNILSETGMPAGALVTGTCLAAAFGCILMGVVANLPFALASGMGLNAFFAYTVVLQMG
                     VPWEVALTAVFVEGIIFIVLSVSGVREAVVNAIPKNMKLAVTGGIGIFIALIGLVNSG
                     IVIGDQATLIKMGRFTPAVIITCVGLIIIAVLDKKRVKGSILFGIVVSSLLAWAFAFI
                     NPEYAQKLGIYLPGGLFKFESLAPIAGKIDLGYVLHPTNIGGFLVVVCTFLFVDFFDT
                     VGTLVGVCSKANMLDEKGNVPNVGRALLTDAVATTVGAGLGVSTVTTYVESSTGVIAG
                     GRTGWTAITVGILFLAAMFFSPVFIAIPSCATAPALIYVGYLMLGTVKDIEFDNITEG
                     VPAFVTIACMALTYSIGDGLTLGILTYVFVNIFYNIFGAKKAEDKKHVSVVMIVLAIL
                     FIIKLWLL"
     gene            complement(5737..6882)
                     /locus_tag="OE968_001955"
     CDS             complement(5737..6882)
                     /locus_tag="OE968_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HCP7219235.1"
                     /translation="MNTFEQLKISSTLIDGLKKQDITSPTEVQSLVIGNIIQNKDLLI
                     NSQTGTGKTLAYLLPIFEKIDTSKRETQALILAPTHELVMQITNQVELLAKNAELSVT
                     SLALIGEVNIQKQIKNIKAVKPHIVIGSCGRVLDLIKQKKLKSHNIKTIVLDEVDNLL
                     NGKNITCIEDIIRTTLRDRQIIGCSASLTDSTIKICDKLMKEFEIIKTKEKSQINPNI
                     NHSYLLGEIRDKFTFLRKALAATNPKKAIVFVNNEKNIEVLVSKLNYHNYKAIGIFGN
                     MEKEDRKNAINKFKLGKAKILITTDLSARGLDIVDVSHVFNLDFPKSKNEYLHRCGRT
                     ARGNRSGNTISIITKKELDIIKDLQKEFNIVITPKTLQNGELIDIIK"
     gene            7135..7842
                     /locus_tag="OE968_001956"
     CDS             7135..7842
                     /locus_tag="OE968_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCP7219236.1"
                     /translation="MLKVINVSKSYKNKKVVSSVSFDVNDGELFGFIGHNGAGKTTTI
                     KAIVGIHDFEEGEVLINSKSIKKQPVECKKEMAYIPDNPDLYESLTGIQYLNFIADIF
                     EVAKDKREELIKYYSNKFELNKALGDLISSYSHGMKQKLAIISALIHSPKILILDEPF
                     VGLDPKASFILKEIMREFCDKGGCIFFSTHVLEVAEKICDKIAIIKDGNIIAYGTTEE
                     VKGSNSLESIFMELIEK"
     gene            7889..9484
                     /locus_tag="OE968_001957"
     CDS             7889..9484
                     /locus_tag="OE968_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCP7219237.1"
                     /translation="MSNLSILIKTNIINEFKLNALKKADGREKQKIMGMMLSVVIIAG
                     LLIFYVTSLSLSLVDILKQINQLEMLLIFGFGLSTLTTIVTSLYKTSSYLFQAKDLDL
                     LTSLPIKESTVLASKILMLVGANYLFSSICMLIPAVVYFLNSDVSITYFPYLILLFLA
                     LPLLPIVASSIIFLFIGQISSRIKYKNLVLIIGSIILMLLYTLLMSRLNSMSVEMLKN
                     SVSISETIRKVYPPIYYFVDALKTGSIVSFLAFIAISIIPFFMFVTLFAKKFKDINAK
                     MSEGYKSKNYEFKGQKTSRPSKALLKKEFKRYTSSFIYFLNSSAGLLFLIVGTILILL
                     FGADKVGELLKLNIDFNLIKIQLLGVFFFIIVMNCTTYCSISLEGKNLWILKSSPIDE
                     REIFWSKILMNFLLNAPLSILCLILVSIRLDFEIQFIIVSICLIVSFSMFVALMGLLS
                     NLLYPNLDWKNEVAVVKRSASMIVTMLVSLAYVIILGGIYVLLGISFLNIYIILASIL
                     TLILDFMIWRIISTKGVRIFKNL"
     gene            9587..10669
                     /locus_tag="OE968_001958"
     CDS             9587..10669
                     /locus_tag="OE968_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HCP7219238.1"
                     /translation="MRKLSKREKDFIQYGFLLFLICITTYLVLTTLDIKLIPKIIRLV
                     NKTYIFLGILTIIVYMIIESIVTHLIINAVQKTKVKFIGIKMATMGFYYNLVTPFASG
                     SQPMQIYALTKYDVSLSKSVAIVTNKTVVFQSTVTVFCGILILLNKSLLMEQVHSVKV
                     LITFGMIMNVSMLLGGLLIVFSPKQVKMIAEVLINFLSKFKTFKFLDSKRDRINHYID
                     DYNYSIKIFIKNVRILVLSILLTVLQLIAYFSIVYCVYKASNLRGVSYVHIMTLQVFL
                     YMAISPIPTPGNVGANEVTFFTMFSNIIPKELLGYSVLLYSGFVYYFILIVSGLFTFG
                     THYTLNSWKKENKVNSNLDKVIEKLN"
     gene            10818..10979
                     /locus_tag="OE968_001959"
     CDS             10818..10979
                     /locus_tag="OE968_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III"
                     /protein_id="HCP7219239.1"
                     /translation="MKQDKQNEKQSEISKIKQSNDNKLEIAQELHVSKNIGNMLGYRI
                     DKKKMNRPS"
     gene            11320..12588
                     /locus_tag="OE968_001960"
     CDS             11320..12588
                     /locus_tag="OE968_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HCP7219240.1"
                     /translation="MEASIHTIASNNLLIIFAIVSITGIICSKLSEIIKVPDVVLYLL
                     VGILIGPSFLKFIDIRGFQIENQLILTFGSAFILYLGGKEISLKVLRNVKISVFLLAT
                     LGVVISAFIMQQVIGFTFGISAMTALLAGTIIASTDPATLVPIFNQVKIKDRVKQTVI
                     SESAFNDATGAILTSAVLAVILSNKFSLGENIYELGTMVIVGVLVGLITGILLLKLVN
                     DKPYGIFKDFAPIISVISVVVAYELSTKLGGSGYMSCFIVGIITGNKKNFKIWLSQKS
                     YDADFYVAETLGTICRMAIFIILGSQVNLAQLSKYFMPSVITVLVLMFIARPLCVLVC
                     TLVDREAKWSKSEILFMMWVRETGVIPAALCGIISAMKVPGYEVISSVVFMTILITLV
                     IQGSTTKLVAKKLGLLEEEVINISEKVSTF"
     gene            12783..13571
                     /locus_tag="OE968_001961"
     CDS             12783..13571
                     /locus_tag="OE968_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD binding domain-containing protein"
                     /protein_id="HCP7219241.1"
                     /translation="MFTVMDIVQPDTVEEAYSILNKRKTNQVIGGSAFLRMGKKRIGT
                     GIELSKLNLDYIKEYEDYVEIGSMTTFRTLETSSIIKNNFGRIIEDSVKNIIGVQFRN
                     VVTVGATVFSKYGFSDLIVALLSLDTEVELYNIGRISLEEFLNRDYEKDLLIKIYIKK
                     TNKNASYKSLRNAKSDYPILNVSVSKHMEQFKLCVGARPQKATIAKQASEFLSNNEIN
                     EINIDKAVEIASEELTFGSNMRASREYRKAMSKVLLKRAIMEVI"
     gene            13571..14020
                     /locus_tag="OE968_001962"
     CDS             13571..14020
                     /locus_tag="OE968_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2Fe-2S iron-sulfur cluster binding
                     domain-containing protein"
                     /protein_id="HCP7219242.1"
                     /translation="MLVKININGKKKSVDIEPEEYLVDTLRKVGNLSVKRGCDTGCCG
                     LCTVLIDKKPTLSCATLTLRALDKEITTIEGLENEVKEFSEVLVKEGAEQCGFCSPGF
                     ILTVLAMKDELENPTDDEIKHYLTGNLCRCTGYMGQLRAIKTYLEVK"
     gene            14024..16288
                     /locus_tag="OE968_001963"
     CDS             14024..16288
                     /locus_tag="OE968_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HCP7219243.1"
                     /translation="MNIVGKGIKKIDGMSITTGKPVYTDDLSAKDALVVKILRSPHAY
                     AKIKDIDTSKAEMVDGVECVLTYKDVPKSRFTLAGQTYPEPSPYDRLILEDVVRYVGD
                     EVAIVAAIDEKTAIKAMNLIKVKYEVLTPVLDFEEAIGNKTMVHDEDRHCNFDIGMQR
                     EKNIVSHHDYTKGDVEKVLSNCDVVIEETYYTQAQAHAMMETYRAYNYLDHMGRLVVV
                     SSTQIPFHVKRHLSRALEIPASKIRVIKPRIGGGFGGKQTACVEIFSAIVTLKTGKPA
                     KIIYDRKETFNCSTSRHAMRLKVRLGATNDGIIKAIDIKALSDTGAYGEHASTTIGLV
                     GEKTLPMYNKVEATRFIADVVYTNKMPAGALRGYGASQGCFAVESTINMLANKLKMDP
                     TDLRLKNVVTEGETTFAYGKTLNSVDLIKCINKGKELIGWNEKYPCKHLDNGKIRSVG
                     MAITMQGSGIQGLDKSSAEIKLNDCGDYTLMIGSTDMGTGSDTILAQMAAEVLDTSIE
                     NITVISADTDLVPYDPGSYASSTTYVTGMAVVKAAQDLREKIISAGATKLGVEKDEVK
                     FDGIKLTSKKGSTLLFDIAVDSTIGPDTNQLIGLASHGSPVSPPPFIAGFAETEIDTE
                     TGKVDLVNYVAVVDCGTVINKNLAKIQVEGGIVQGIGMALFEEVRYTEKGRMDTNTFM
                     QYKIPARCDIGNVKVDFVETYEPTGPFGAKSVGEVVINTPLPAIQEAVFNGIGVRINT
                     LPITPEKVFMEMNK"
     gene            16428..16739
                     /locus_tag="OE968_001964"
     CDS             16428..16739
                     /locus_tag="OE968_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219244.1"
                     /translation="MAGNLNNMRAVNNFRGDKNILECLVSFEGRSISQRKVRVFFKEK
                     QNQIEIDFAEEEISKLVENVVLNTSYQEMLYDEIEKQLEIDCIGTWMILSKLKDGSRV
                     H"
     gene            17025..17525
                     /locus_tag="OE968_001965"
     CDS             17025..17525
                     /locus_tag="OE968_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HCP7219245.1"
                     /translation="MRKNSINIALTAAITAIYAVLTLSLGFISYGPIQFRVAEIMMLL
                     AFLDKGYIVGLTLGCFLANVIGPYGVPDIIFGTLATFISASMIYITRKLGKQNKSTLV
                     IASLWPTVINSIVVGLMLNVFFGLPLILSMIQVGFGEFVVVTIVGVPFFCFLMKKYKN
                     VINIKF"
     gene            17582..18568
                     /locus_tag="OE968_001966"
     CDS             17582..18568
                     /locus_tag="OE968_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WYL domain-containing protein"
                     /protein_id="HCP7219246.1"
                     /translation="MSKVKRLTDVWIYINDKQKFTIKELSEEFNLSAKTIQRYLKELN
                     KMGLPIQAEQGRNGGYRVLNNSYIPPVIFTEKEVMIILFALKSLQIYNYKLMEIEINS
                     IMRKVSYERKSSIKVGIENIKRYIGFVANDTNDGDFKSSNVTEFFRASSESLILNIKY
                     KCGNQILEKNVCPIGIYLNKGAWFSPAYDCKSDKIILVHIDNIIDIKRTGESKKIHIN
                     LEEWLHEVYNNLYGNSSTTKKFGEIIYLNVLLTKEGVSKIKDSSWNLDMELNEDGSGI
                     ISTFIKVEDIDCYASILFFIGNNAKVIEPKFLNKLLYDKANELRYFYEENMV"
     gene            18618..19340
                     /locus_tag="OE968_001967"
     CDS             18618..19340
                     /locus_tag="OE968_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein"
                     /protein_id="HCP7219247.1"
                     /translation="MENFNKNAKIIGIGAEGINIINEVEEKIKANMDIEKININQEIE
                     KEYVRSLLDGVDILFLIYSSEDKHIRDIIKAVSYMSNERRVLSIGMDCSEKENKEDLE
                     LGREFKINNDSIFKFVDLMNIMVESISDSCMINIDITDLKEAIVGDKGIKYSFEEFED
                     TKSYSEIADILFDRMEYIGEEFISKKGIVFVEGSPEFSIMELNDLISNIQSKVEESYE
                     VIFSLYIKENLNGNIRVGLLYN"
     gene            19369..21303
                     /locus_tag="OE968_001968"
     CDS             19369..21303
                     /locus_tag="OE968_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HCP7219248.1"
                     /translation="MSENIRGTEYWLMEEFFYQETDTPQIFREESIIALGFDIKINLK
                     KVFSMGKKSEKYINENCNDKDFIKKFMSIKKGDYFLYKAYQNIEEKVKCNVSIGIVEE
                     DFENGYELSHILGHTLPVKWMHNFDTVSNCKVYTSEFYKLNNNDISSYLEIIKSQDKK
                     LLRKRIEESENNKWYLKNYYYKNVDKCVDDEELFIQPINLEQLESLKNIKTDDYILLY
                     NSEKVICENDHTMKSLFGVCQVMEGFDKEKVSALEGGYFFPVRWIEYEKENIDGNAWV
                     IFENNSIVEKYVKRFTNKMPLNTILYGPPGTGKTYNTKQMVYNLVSETSLRNKYYTGY
                     LDYKNNVEFCTFHQSYGYEEFIEGLKSDGEGNFKQEDGILKDISIEACYNALKFEKKM
                     SFELEKDSLTLETIKDRKKKLVLENIEYSESFNFEESENYVLIIDEINRGNVSKIFGE
                     LITLLEDDKRLTKSNQTIVKLPYSKEKFSLPPNLYIVGTMNTSDKSIALLDIALRRRF
                     NFEEIMPDYDLLSIVDGIDIRKMLYTINKRIEFLYDRDHVIGQAYLLAVENINDIVVV
                     FRSKIIPLLQEYFYYDSEKVGLILGGIGRNEKDKYIVYKEKLIASELFKNNNASIMES
                     KVNYCIKQNISSEELKNIYE"
     gene            21296..21958
                     /locus_tag="OE968_001969"
                     /pseudo
     CDS             21296..21958
                     /locus_tag="OE968_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112798.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(22079..22891)
                     /locus_tag="OE968_001970"
     CDS             complement(22079..22891)
                     /locus_tag="OE968_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HCP7219249.1"
                     /translation="MFYNAKSCQMMIGSNTVNYIEFGSGKKTLIILPGLGDGLFPLHG
                     KIQAIAFAFRYKQFAKDYKVYVFSRKNQITEKYSTRDMAKDQADIMKKLGIMKAEVMG
                     VSQGGMIAQYLAIDYPELVEKLVLAVTSSKQNDTIQNVICSWIDMAKKQNYNDLMIDT
                     AKKSYSERYLKKYQLFIPFLGKVGKPKDFKRFIIQATSCIEHNAFSELNKITCPTLII
                     GGANDKIVGNNASFHLAEKIKKSEIFIYEGLGHATYEEAQDFNERVLEFLNK"
     gene            complement(22914..23546)
                     /locus_tag="OE968_001971"
     CDS             complement(22914..23546)
                     /locus_tag="OE968_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCP7219250.1"
                     /translation="MNREEKSKNSKEKIIQSAFSLFSSKGYDSTSTQDIINLSGLSRG
                     AMYHHFKTKEDILRSVTKELYSQMNNFLEHLVADDTLTANEKIIELVVHSANDYTRRK
                     MVHCSWLEKIPFALIEEVRNLNNVVAPNIAKIIKQGVENKEFSCEYPEELAEMLVFSI
                     DILLDPVLFKREYSEVCNRLDFLLFMLKKMDIPLIDEYGIQKFKDLFRQL"
     gene            complement(23890..25545)
                     /gene="ilvD"
                     /locus_tag="OE968_001972"
     CDS             complement(23890..25545)
                     /gene="ilvD"
                     /locus_tag="OE968_001972"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020457899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HCP7219251.1"
                     /translation="MRSDIKKGIEGAPKRALMYGMGLTKEEIERPLIGIVNAQNEVIP
                     GHLHLDEIAEAAKNGVRMSGGLPLEFPAIGVCDGIAMGHVGMNYSLASRELIADSIEA
                     MAMAHGFDALVLIPNCDKIVPGMLMAAARLNIPSIVVSGGPMLPGKKNGKVYDFNSAM
                     EGVGACKDGTVSEEELEALAMNSCPGCGSCSGLFTANSMNCLTEALGMGIPYNGTAAS
                     HSGERKRIAKYAGMYVMELLKNDIKPRDILTIDAFKNAIAVDMAMAGSTNTVLHLPAI
                     AYESGIELNLNFFDEISEKTPCLTKLSPSGKHHIEDLHMAGGIPAIMNELSKINGINL
                     DCKTVTGKTIGENIRNCEIENEEVIHTLKNPYSNQGGLAILKGNLALNGAVVKKSAVA
                     EEMLVHEGPARVFNSEEEAVNAIFGKKINKGDVIVIRYEGPKGGPGMKEMLSPTSAVA
                     GMGLDKHVALLTDGRFSGATRGASIGHISPEAMEGGLIGLVEEGDIISINIPDKKLEL
                     KVDEVEIENRKLKFKPLEPKIKHGYLSRYAKLVTSANTGAVLK"
     gene            complement(25869..26168)
                     /locus_tag="OE968_001973"
     CDS             complement(25869..26168)
                     /locus_tag="OE968_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219252.1"
                     /translation="MKWIKWYSITCICIFIVVAFYMFIFPNKIETIDTSSAYSFVEKK
                     VPNSAVYQGYKKNPVDGTTTIYYSYDNSTHIVRLSHPEDYSRKINWDKVSNIRFD"
     gene            26428..27108
                     /locus_tag="OE968_001974"
     CDS             26428..27108
                     /locus_tag="OE968_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HCP7219253.1"
                     /translation="MIWTFYSFICVILPCLIYQIVVIKRKNLKVEKNVMIHLVWVYIF
                     LLYIYLALSKAGIGSIWDIGRYSGLFRIDEINLIPFDSVGILTYILNIIMFMPLGFLL
                     PLIWKNFRNIINVSLTGLGFSLAIELCQLFNLRATDIDDLMMNTLGAVLGYFIWVGVN
                     NLFNLIKKKDIFPSIYKNIIQDEIAITIDDDISEKITSLYKNEAIIYLILAVLGEFLL
                     FNWSIIPY"
     gene            complement(27218..27475)
                     /locus_tag="OE968_001975"
     CDS             complement(27218..27475)
                     /locus_tag="OE968_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219254.1"
                     /translation="MIIIRSQDKTNLMQINQIKIDGSQVYAVFESKIDTVKIGDYENN
                     TRAIQVLDNIQNFIENGTKYDYITSNKVRYNVNKIFQMPAK"
BASE COUNT        10269 a         3255 c         4256 g         9785 t
ORIGIN      
        1 ttaatttaat ataaaaagta tgttttttct aactatatat ttagaattta gtaaataaaa
       61 aaattataaa actaagaagg aaaagtaaaa caataataaa aaataaaaaa caataagcaa
      121 aatgttgaaa ataataccaa atcaatatat aataagaata aagaaagatt aaagggggat
      181 attttaatgc aactaatctt agatacaggt aatgtggagg agattaagga gttatgtact
      241 tgtttaccaa tagatggtgt aactacaaat ccaagtattg tttcaaaaga aaaaaagaat
      301 tttaagcaac ttataaatga aattggtgag attataggtg aggatatgcc tatacatgct
      361 caagtgttaa gtacaaagta tgaagaaata ttagaagaag cattatatat aagtagtttg
      421 agaaaaaata tatatgtaaa aatacctgta acacaagatg gtttaagagc tataaaagac
      481 cttcatagaa aaggtgtaaa aataactgct actgcaatat tcactgctca tcaaggtttt
      541 ttagctgcaa aggctggagc aaattatatt gcaccttatg taaataggct tgataatata
      601 tctggtgatg gagtagctat ggtttcagaa cttataaaaa taatagatac ttataaaatg
      661 gatacaaaag tacttgcagc cagttttaaa aatgcacaac aagttataga attaatgcaa
      721 catggggtgc atagtgttac agtaccatat gatatttgta aatctatgat gaatcatcca
      781 ttaactgatt ggagtgtaga taagtttata gaggattggg agaatacttt tggaaaagga
      841 agtaaaacaa ataatattta gtattatggt aaaagagtag ttttgtccaa ttttacaaga
      901 acttatataa aaagatgaaa atatgaattt tctttttaat aatttcgtta ttatcttaag
      961 ttaattcata ttttcatctt ttttagattt ctagtcctat aaatttccac caagggaatg
     1021 ttatacatat tattataaag taggttaaag gaatcaaagt taaaccgtat ttgaaaataa
     1081 ccttgctatt atacagattt tcaccatgac caaccattat tgtagcatga tgaaatggta
     1141 atatgtactg tatgcttact ataatgtaga caaatagaca taaagtaaca ctattttcct
     1201 ttagtatatg taaacttcca agtaatggta ttactacaga tgatgtagtg acagcacttc
     1261 caagacatat attcaagatt attgtgagag ttatcaaaaa caatattgaa ataatttctg
     1321 aagagtttgg tataaacttt atcaaataat ttcccattat atctacaact ccagagtact
     1381 ttaacactcc tccaattgaa aatgctgcta taaaaaaaat aaggaccttc caatttattt
     1441 cttttaaagt actaaatcca actatttttc ttagtaataa aagaagtaca caaattgaca
     1501 ttataattaa tgtgtttatg ttatgtatga actgagttaa aaacataaaa aacattattc
     1561 ctaggcataa aaatacgtgt ttttgttctt tgtttagcaa attaaattct ttttttaaat
     1621 tagaatatga aaaatgaagt ttattaccct caagattttc attagaaata aattttattg
     1681 aatgcaattc ttttttaaag acaaaggtaa ataaaaaata agttataaaa caagtaatta
     1741 tagttggaac agacatataa aaagcccatt gaccccaatt tatattacaa tttccaagtt
     1801 ctagtacaac ataatttaga agagtgtctc catttacaaa aaacattgat gtaaaggtag
     1861 atgctgtaaa tatactaaat aaaagtatag attttgaatc ttcagttatc tgttgttctt
     1921 ttaaaaactc cttgtaaaaa gcagatacaa gaataaccct tggaaatggt tgtgggataa
     1981 aaaatattaa aagtatacct aaaatatacg ataaaagaat cattttttta ggggtattta
     2041 cagtatttaa aattaacttc tcagaaataa tttttgcgac acctgttttt gtaactgcat
     2101 tagtaattat gtatgcaaga attattatgt aaaaattttc tgtaaataaa aactgtaaaa
     2161 taacctttat tggtgcaatg ttaaatataa acgctagaat tacaaaaaac aatgcaacaa
     2221 aagttttttc aactgagtct acagcccata tcaagatagt taaaaaagat aagcatatag
     2281 aaaattttat gttgaaactg taattaagag agaagtagag aattatggta gctataacag
     2341 tcatataaaa ttgttttggc ttaagaataa tacccatttt tatattcacc tccataattt
     2401 attatatcat aatggaggtg aatacaatga atgtgaatac attttataaa aagattattc
     2461 attgattcta tgatttacaa tagctttagt tttccaatgt cctttcttat agtagataac
     2521 tgtaacaata agacctaaag tccaaccaaa aggaataccc atccaaattc cgtctgttcc
     2581 aaaaaattta gaaagcatat aagaagctgg aagtcttcca agccataaag atactattga
     2641 gcttataagt gcaaacatgg aatcaccagc acctttcatt gcacttgaaa gtacaaaaga
     2701 agttccaata aataagaaga atggtcctat tataaataag taagaagagc caattttaat
     2761 gacatcttta tcagtattga atagagcaat tagattttcc ctaaatagca aaattaaagc
     2821 aataactgta actgctaaaa ctaaggtcat ttttatagat tctcgaatgc cttttttaac
     2881 tctttcattt tctccagcac ctatgttttg agcaacaaaa gtagaaacag cagaaccaag
     2941 attcataata ggtaagctta taaaattttc tatcctaaga ccagcaccaa aagctgccat
     3001 agcagatgta ccataactat taactaaaaa ttgaagagcc atatttccaa ttgaaaacaa
     3061 catttgttga actccacttg gaagtcctaa tctaagtcca tctttaaata ttttgttatc
     3121 atatacaatt cccttgattt taaatttaag cacttcatgt tttttattta aataaattat
     3181 acttattata aatgatactg cctgagccat tatagtggca agtgcaacgc cctcaacacc
     3241 cattcttagc actacaataa aagttaagtc taaaactata tttagaattg tggctattat
     3301 cagaaaataa agtggagtta ctgaatctcc aagtcctcta agtattgcac ttactgaatt
     3361 atatccagca gaaaataata ttccactaaa tattatagta agatacaatt ttgattgagc
     3421 aaaaacggat tctggtgtat tcataagctt aagcattggg ccaccaaata ctattccaag
     3481 aatacttatt aatatagaac caataaataa aagtatatat gtagtatcaa tagtagcttt
     3541 tacctttttt aaatctcctg agccataaaa ttgtgacact aaaatagaaa atccaaggct
     3601 aacacccata agcgctgcca ccaataaaaa cattataggg ttagctccag agactgccgc
     3661 cattgcttct tttccaataa atctaccaac tattatactg tcagctgtat tgtatagttg
     3721 ttgaaataaa ctaccaataa gcataggcat ggcaaaaaag aatatggact ttccctcatg
     3781 acctgtagtt aaatctttca ccttattcct ccaaataaaa aaattattaa tttattatag
     3841 tataatctta acataaactt tatatccaaa ctataaataa attgtatcaa aatatcatat
     3901 atttttttaa aatgtaaaga atataattat aatttgaatt taataaatca atatttaata
     3961 taatcgaata ttaatacaaa atcaatacaa tatatacgta tatattgaca aaattaatta
     4021 tataaattaa aataatattc gtaaagaaaa attcatgttt tgtactgtat aacatataat
     4081 tttgacaata tgggtcataa gtttctaccg gaataccgta aatattctga ctatgtatac
     4141 tattatttag ttaattaaat atttaattaa ctgaattatg aaggatacgg ctcagcttat
     4201 caactactgt gtcgtttttt tgtaaaattt aataggaggt gttgttatgc aaacaacaaa
     4261 cagtagtact atgcagaaac tttttccaat tttgactaat aaaaatgtcg acatgaagaa
     4321 ggaaataatt gcaggagtaa ctactttttt aactatggct tatataatag ctgtaaatcc
     4381 aaatatttta tctgagacag gcatgcctgc aggtgcactt gttacaggta cttgtttagc
     4441 agcagcattt ggatgtattt taatgggtgt agttgctaac cttccttttg ctttagcatc
     4501 aggtatgggt cttaatgcat tttttgcata tacagtagtt ttacaaatgg gtgttccttg
     4561 ggaagtagct cttacagcag tatttgtaga aggtattatt tttatagtat tatcagtaag
     4621 tggagttcgt gaggctgttg taaatgcgat accaaaaaat atgaaattag ctgttacagg
     4681 tggtatagga atatttattg cacttatagg tctagttaac agtggaattg ttattggaga
     4741 ccaagccact cttatcaaaa tgggtagatt tacaccagca gtaataataa cttgtgtagg
     4801 attaataatt attgctgtat tagataaaaa aagagttaaa ggttctatac tttttggaat
     4861 agtagtgagt tcattacttg cttgggcatt tgcttttata aatccagagt atgcacaaaa
     4921 attaggtata tatttacctg gtggattatt taaattcgaa agtttagcac caatagcagg
     4981 taaaatagat ttaggatatg tactacatcc aacaaatata ggtggttttt tagtagtagt
     5041 ttgtacattt ttatttgttg atttttttga tacagtaggt acattagttg gtgtttgttc
     5101 taaagcaaac atgttagatg aaaaagggaa tgttcctaat gtaggtagag ccttacttac
     5161 agatgcggtt gcaactacag ttggtgcagg acttggagta tctacagtta caacttatgt
     5221 tgagagttca acaggagtta tcgcaggtgg aagaactgga tggacagcaa taacagttgg
     5281 aattttattc ttagctgcaa tgtttttctc tcctgtattt atagcaattc catcatgtgc
     5341 tacagcacca gctttaatat atgttggata tttaatgctt ggtacagtta aggatataga
     5401 gtttgataat ataactgaag gtgttccagc ttttgttact attgcttgta tggcattaac
     5461 atatagtata ggtgatggtt taactttagg tatattaact tatgttttcg taaatatatt
     5521 ttataatata tttggagcta aaaaggcaga agacaaaaaa catgtttctg tagtaatgat
     5581 tgttctggca atattattta taataaaact ttggctacta taataggtat tatttaaaat
     5641 tttaatttaa tataaaataa agggctgtaa tttattatca attgtgatga taaactacag
     5701 ctcttttgta tttgttgtat ttttgtattt attgtattat ttaataatgt ctattagttc
     5761 tccattttgt aaagttttag gtgtaattac tatattgaac tctttttgca aatcttttat
     5821 aatatctaat tctttttttg ttattattga gattgtgtta ccacttcgat ttcctctagc
     5881 agttcgacca catctatgca ggtattcatt tttacttttt ggaaaatcca agttaaaaac
     5941 atgacttaca tccacaatat ctagtccacg agcagataaa tcagttgtaa ttaaaatctt
     6001 tgctttacca agtttaaatt tatttattgc attctttcta tcttcttttt ccatatttcc
     6061 aaaaattcct attgctttgt aattatgata atttagtttt gatactagga cttctatatt
     6121 tttttcatta tttacaaata caatagcttt ttttggattt gtagctgcta atgcctttct
     6181 aagaaaagta aatttatccc ttatctcacc taataaatat gagtgattga tgttaggatt
     6241 tatttgtgat ttttcctttg tttttattat ttcaaactcc ttcataagtt tatcacaaat
     6301 ttttatagtg ctatcagtaa gacttgcaga gcatcctata atttgtctat ctcttaacgt
     6361 tgttcttatt atgtcttcta tacaagttat attttttcca ttcaatagat tgtccacttc
     6421 atctaagaca atagttttta tattatgtga ttttagtttc ttttgtttta tcaagtctaa
     6481 aactcttcca caagagccaa ttactatgtg tggttttact gcttttatat tttttatttg
     6541 tttttgtata ttgacctccc caattaaagc taaagaagta acggagagtt ctgcattttt
     6601 agccaataat tcaacctggt ttgtaatctg cattactaat tcatgcgtag gtgcaagtat
     6661 aagagcttgt gtttctcttt ttgatgtatc aattttttca aatataggta aaaggtacgc
     6721 tagtgttttt cctgttccag tctgtgaatt aatcaataaa tccttatttt gaattatatt
     6781 ccctataaca agtgactgaa cttctgttgg agaagttatg tcttgttttt tgagtccatc
     6841 tattagagtg gaacttattt ttaattgttc aaatgtattc atattttact ccttatattt
     6901 taataattat agtcaactat tttttattat acattgttta ttcaaatcga actatatatt
     6961 cttttataat tatgtgtaat ttgaaagtaa atatcaatta tatttatacc tttatatttc
     7021 tgataccttt gcattttata gatttctaaa ataaacaaat aaaagttgta attgtttgat
     7081 atttgttata tattgtatat aacaaatatc aaaactataa tatggaggga aattatgtta
     7141 aaagtaatca atgtatctaa atcatataaa aataaaaaag tagtaagtag tgtctcattt
     7201 gatgtaaatg atggagagct ttttgggttt ataggacata atggagcagg taaaactact
     7261 actattaaag caattgttgg aatacacgat tttgaagagg gagaagtact aataaattct
     7321 aaatctataa aaaaacagcc tgttgaatgt aaaaaggaaa tggcatatat acctgataat
     7381 ccagatttat acgagtcatt aactggtata caatacctta attttatagc tgacatattt
     7441 gaagttgcca aagataaaag agaagagtta ataaaatatt attcaaataa gtttgaactc
     7501 aataaagcat taggagattt aatatcttca tattcgcatg gtatgaaaca aaaattagct
     7561 ataatttcgg ctttgataca cagtccaaaa atcttaattc ttgatgaacc ttttgtaggt
     7621 cttgacccaa aagcttcctt tatattgaag gaaattatga gggagttttg tgacaaaggt
     7681 ggttgtatat ttttctcaac acacgtttta gaagttgctg aaaaaatttg tgataagatt
     7741 gccataataa aagatggaaa tataattgct tatggaacta cagaagaagt taagggaagt
     7801 aattcacttg aaagtatctt tatggaatta atagagaaat aaaatgtttt ttatacaata
     7861 tagtgtctaa agtgaggaat gataaaatat gagcaatcta agtatattaa taaaaactaa
     7921 tataataaat gaatttaaat taaatgcgtt aaaaaaagct gatggtagag aaaaacaaaa
     7981 aataatggga atgatgcttt cagttgttat aatagcgggt ctattaattt tttatgtaac
     8041 aagcttaagt ctctctttag ttgatatctt aaagcaaata aatcaactgg aaatgctact
     8101 gatatttggt tttggattat caacattaac aactattgtt acatcattat ataaaacgtc
     8161 atcatatcta tttcaagcaa aagatttaga ccttttgact agtttaccta taaaagaatc
     8221 tactgtacta gcaagtaaga tattaatgtt ggttggagca aactatttat tttcttcaat
     8281 atgtatgctt atacctgcag tggtttactt tttaaattct gatgtaagta taacttattt
     8341 cccttatttg atattgctat ttttagcttt accattatta ccgatagttg cttcatcaat
     8401 aatttttcta tttatagggc agatatcatc aagaataaaa tacaaaaatt tagtattaat
     8461 cataggtagc attatattga tgttgcttta taccctactt atgtcaagac ttaattctat
     8521 gtcagttgaa atgctaaaga atagtgtgtc tatttcagag acgattagaa aagtatatcc
     8581 tcctatatat tattttgttg atgctcttaa aacaggaagt atagtttcat ttttagcatt
     8641 tatagccatc tcaataatac cattttttat gtttgtaact ctgtttgcaa aaaaatttaa
     8701 agatataaat gctaagatga gtgaaggata taagtcaaaa aattatgaat ttaagggtca
     8761 aaaaacttca agaccttcaa aagctttatt aaaaaaagaa tttaagagat atacttcttc
     8821 gtttatatac tttttaaatt catctgcagg tttgttattt ctaatagtag gtacaatttt
     8881 aatattatta tttggagcag ataaagtggg tgagttactg aaattgaata tagattttaa
     8941 tcttataaaa atacaattat tgggagtatt cttctttata atagtaatga attgtacaac
     9001 atactgttca atttctcttg aaggaaaaaa cttatggata ctgaaatctt ctccaataga
     9061 tgaaagagaa atattctggt caaaaatatt gatgaatttt ttattgaatg caccactatc
     9121 tattttatgt ctaatattag tatctataag attagacttt gaaattcagt ttattattgt
     9181 atcaatctgt ttgattgtaa gtttttcaat gtttgtagca ttgatgggat tattatcaaa
     9241 tttattatac ccaaaccttg attggaaaaa tgaggtggct gtagtaaaaa gaagtgcaag
     9301 tatgatagtt acaatgttag tatcattagc ttatgtaatt atacttggag gtatatatgt
     9361 attacttgga atttcgtttt taaatatata tattattttg gcaagtatac ttactttgat
     9421 attagatttt atgatatgga gaattatttc tactaaagga gtaagaatat ttaaaaattt
     9481 ataggtgtat ttatgtcaaa taaagactta tcttttttag tcttgcaaat aataggttaa
     9541 gtagtatact atgtatagtg atatgaaaaa atttaggaga aaataaatga gaaaattatc
     9601 caaaagagaa aaagatttta ttcaatatgg atttttatta tttttgatat gtattactac
     9661 ttatttagta ttaactactt tagatataaa actaatacct aaaattataa ggctagtaaa
     9721 taagacttat atatttcttg gcatattgac aattatagta tatatgataa ttgaatctat
     9781 tgtaactcat ttgataataa atgcagttca aaaaacaaaa gtaaaattta ttggtattaa
     9841 aatggctaca atgggatttt actataactt agttactcca tttgcatctg ggagtcaacc
     9901 aatgcaaata tatgcactta caaaatatga tgtaagcctt agtaaatcag tggctatagt
     9961 tactaataaa actgtagtat ttcaaagtac agttactgta ttttgtggaa ttttaatttt
    10021 gctaaataag tcattactga tggagcaagt acattctgtg aaagtcttga taacttttgg
    10081 aatgattatg aatgtaagta tgttgttagg tggactacta atagtattta gtccaaaaca
    10141 agtaaaaatg atagcagaag ttttgattaa ttttttatct aaatttaaaa catttaaatt
    10201 tttagattca aaacgtgata gaataaatca ttatattgat gattataatt attctataaa
    10261 aatatttatt aaaaatgtaa gaatcttagt tttaagtata ttacttactg tgttacaatt
    10321 aatcgcatat ttcagtatag tttattgtgt gtataaagcc tcaaatttaa gaggagtttc
    10381 atatgtacat ataatgacat tacaggtctt tttatatatg gctatatcac caattccaac
    10441 accaggaaat gttggagcta atgaggttac attttttact atgttctcca atataattcc
    10501 aaaagaatta ttggggtact ctgtactctt atatagtggg tttgtatact attttatatt
    10561 aatagtttca ggtttattta catttggaac gcattataca ttaaattctt ggaaaaagga
    10621 aaataaagta aattctaatt tagataaggt tattgaaaaa ttaaattaat aaaataatta
    10681 gggaaattct atatataaat atggtgttga ataagctata ttatattgag atatttccct
    10741 tttttgatta aaattataga aatttgaaat aataagtaat aaacagaaaa agtgatattg
    10801 ttttgaaagg agaaactatg aaacaagata aacaaaatga aaaacaaagt gagatttcta
    10861 agataaaaca aagcaatgat aataaacttg aaatagctca agaattacat gtaagtaaaa
    10921 atatagggaa tatgcttgga tatagaatag ataagaaaaa aatgaataga ccaagttaat
    10981 gaaaatgttg aaaatggtac attttaaaaa atatatataa tgaaatgttt tattgttaaa
    11041 tttaaactta ttttaatggg ggaaaaagtc gaaaaatatc taaaaagata tggatataaa
    11101 aaatattaat atatatatac tataaacttg acaaaatcaa ccttttaata actagcaaaa
    11161 aatagcaaaa ttatataagc gttatttaat tgtcaaaaat gaaagctaaa ttgcatgtcc
    11221 taaaaaaaat gattgataac atttatttgt gtgctataat tatatagtaa aacaataagt
    11281 atattgcata atgtatgcaa atcgggagga gagacggaca tggaagcatc tatacacaca
    11341 attgccagca ataatttatt gataattttt gctattgtaa gtataactgg aataatttgt
    11401 agtaagctta gtgaaataat aaaggttcca gatgtagtgt tatatttact tgtaggtatt
    11461 ttaataggac catcattttt aaaatttata gatattcgtg gatttcaaat agaaaatcaa
    11521 ctaatactta catttggttc tgcatttatt ttatatttag gtggaaaaga aataagttta
    11581 aaagtattga gaaatgtgaa gatatctgta ttcttattag ctactttagg agttgtgata
    11641 tctgctttta taatgcaaca agtaatagga tttacttttg ggataagtgc aatgactgct
    11701 ttactagcag gaactataat agcatcaaca gacccagcca ctcttgtacc tatatttaat
    11761 caggtaaaga taaaggatag ggtaaaacaa actgtaataa gtgaatcagc ttttaatgat
    11821 gcaacaggag ctatactaac atcagcagtg ttggctgtaa ttttgtcaaa taaattttca
    11881 ttaggtgaaa atatttatga actggggaca atggttattg tcggagtttt agttggttta
    11941 attacaggaa tactgctttt gaaattagtt aatgataaac cttatggaat atttaaagat
    12001 tttgcaccaa taatatctgt tatttcagtt gtagttgcat atgaattatc tacaaaatta
    12061 ggtggaagtg gatatatgtc ttgctttatt gtaggtataa taactggtaa caagaaaaac
    12121 tttaaaattt ggttaagtca aaaatcttat gatgcagatt tttatgttgc tgaaacttta
    12181 ggtactattt gtcgtatggc aatatttata atattgggta gccaagttaa tttggctcag
    12241 ttaagtaaat attttatgcc atctgtaatt acagtattag tattaatgtt tatagcaaga
    12301 ccactttgcg ttttagtttg tacacttgta gacagggaag caaaatggag taaaagtgaa
    12361 atattattta tgatgtgggt aagggaaaca ggcgtaatac cagcagcact ttgtggtatt
    12421 atttcagcaa tgaaagttcc tggatacgaa gtgatttcat ctgtagtatt tatgactata
    12481 ctaattacat tagtaataca aggaagtact acaaaattag tagctaaaaa acttggatta
    12541 ttagaagaag aagtgataaa tataagtgaa aaagtatcaa ctttttaaag ttttgcttta
    12601 aaatagtacc tgttaatggc tattttaata ttgtctaatg atgattattg aaatagtcat
    12661 ttttttatgt ataagtaatt tacagaattt acatattaga catatttatt atcaaaattt
    12721 gttgaagcta tgatataatt agttgtattt aaaataagaa tagcaaataa gggaggaaat
    12781 ttatgtttac ggttatggat attgtacagc cagatacagt agaagaagcg tactcaattt
    12841 taaataaaag aaaaactaac caagtaattg gtggaagtgc ttttttaaga atggggaaaa
    12901 aaagaatagg aacaggaata gaattatcta aattaaattt agattatata aaagagtatg
    12961 aagattacgt tgagattggt tctatgacta cttttagaac attagaaaca agttccataa
    13021 taaaaaataa ttttggaaga ataatagaag attcagttaa aaatataata ggagttcagt
    13081 ttagaaatgt agtaacagtt ggtgcaacag tattttctaa atatggtttt tctgacttga
    13141 tagtagcatt actttcatta gatacagaag tagaattata taatattggg agaattagtc
    13201 ttgaagagtt tctaaataga gattatgaga aagatttact tattaagata tacataaaga
    13261 agacaaataa gaatgcttct tataaatcac ttagaaatgc aaagagtgat tatccaattc
    13321 taaatgtatc tgtatcaaaa catatggaac aatttaagtt atgtgtagga gcaagaccgc
    13381 agaaagctac gattgcaaaa caagctagtg aatttctatc taacaatgaa atcaatgaaa
    13441 ttaatataga taaagcagta gaaatagcat cagaagaact aacttttggt tctaacatga
    13501 gagcatctag ggagtataga aaagctatga gtaaagtact tttaaaaaga gctataatgg
    13561 aggttattta atgttagtaa agattaatat aaatgggaag aaaaaaagtg ttgatataga
    13621 accagaagaa tatctggttg atactttaag aaaagttggt aatttaagtg tgaaaagagg
    13681 ttgtgacaca ggctgttgtg gtttatgtac agttttaatt gacaagaaac ctacattatc
    13741 ctgtgcaaca ctgacattga gagctttaga taaagaaata actacaattg aaggtttaga
    13801 aaatgaagtt aaagaattta gtgaagtttt ggtaaaagaa ggagctgagc aatgtggttt
    13861 ctgttctcct ggctttatac ttactgtact tgcaatgaag gatgagcttg aaaatcctac
    13921 agatgatgaa ataaagcatt atcttacagg aaatctatgt agatgtacag ggtatatggg
    13981 acagttaaga gctatcaaaa cttatctgga ggtaaaatag aacatgaata tagttggaaa
    14041 aggaatcaag aaaatagatg gaatgagtat cacaacagga aagcctgtat atacagatga
    14101 tttatcagca aaagatgctt tggtggtaaa gatacttaga agtcctcacg cttatgcaaa
    14161 aataaaagat atagatacat caaaggcaga aatggttgat ggtgttgaat gtgttttaac
    14221 atataaagat gtaccaaaat ctcgatttac acttgctggt caaacatatc cagagccatc
    14281 tccatatgat agattaattc ttgaagatgt tgtaagatat gtaggtgacg aagtagctat
    14341 agtggcagct atagatgaaa aaactgcaat taaagcaatg aatcttatca aagtaaagta
    14401 tgaagtactt acacctgttt tggattttga agaggcaata ggaaataaaa ctatggtaca
    14461 tgatgaagat agacattgta actttgatat aggtatgcaa agagaaaaaa atatagtatc
    14521 ccatcatgat tatacaaaag gtgatgtaga aaaagtatta agtaattgtg atgtagtgat
    14581 tgaagaaact tattatactc aagctcaagc acatgcaatg atggagacgt atagggcata
    14641 caattattta gaccatatgg gaagattggt tgtagtaagt tcaactcaaa taccatttca
    14701 tgtaaaaaga catttatctc gtgcactaga aataccagct agcaaaatta gggttataaa
    14761 acctagaatt ggtggcggat ttggtggtaa acaaactgca tgtgttgaga ttttttctgc
    14821 aattgttact ttaaaaacag ggaaaccagc taaaataatt tatgatagaa aagaaacttt
    14881 taattgttca acaagtagac atgcaatgag attaaaagtt agactaggtg ctacaaatga
    14941 tggcataata aaggcaatag atataaaagc actttctgat acaggagcat atggagagca
    15001 tgcttctaca actattggtt tggttggaga aaaaacttta ccaatgtata ataaagttga
    15061 agcaacaaga tttattgcag atgtggtata tactaataag atgccagcag gagcacttag
    15121 agggtatgga gcatcacaag gatgttttgc tgttgaatca actataaata tgcttgctaa
    15181 taaattaaaa atggacccaa cagatttaag gttaaaaaat gtggtaacag aaggtgaaac
    15241 tacatttgca tatggtaaaa ctttaaatag tgtcgattta ataaaatgta taaataaagg
    15301 caaagaactt attggatgga atgaaaaata tccttgtaaa catcttgata atggaaaaat
    15361 tagaagtgtg ggtatggcaa ttactatgca aggttctggt atacaaggtc ttgataagtc
    15421 ttcagctgaa ataaaattga atgactgtgg agattatact cttatgatag gttctactga
    15481 tatgggtaca ggaagtgata cgattttagc tcaaatggct gctgaggttc ttgatacaag
    15541 cattgaaaat ataacagtta tatcagctga tactgactta gttccatatg acccaggttc
    15601 atatgcttca agtactactt atgtaacagg tatggcagta gttaaggcag ctcaagactt
    15661 aagagaaaaa ataatttctg ctggagcaac taaactaggt gttgagaagg atgaagtaaa
    15721 atttgatggt ataaaattaa ctagtaaaaa aggtagcact ttattattcg atatagcagt
    15781 tgattctaca attggtccag atactaatca attaataggt cttgcttctc atggtagccc
    15841 agtatctcct cctcctttta tagcaggttt tgcagaaact gaaattgaca cagaaactgg
    15901 aaaagttgat ttagtaaatt atgtagctgt agtagattgt ggaacggtta taaataaaaa
    15961 tctagctaag atacaagttg aaggtggaat tgttcaaggg attggaatgg cattatttga
    16021 agaagttaga tacacagaaa aaggaagaat ggacacaaat acatttatgc aatacaagat
    16081 tccagctaga tgtgatattg gaaatgttaa agtagatttt gttgaaactt atgaaccaac
    16141 tggaccattt ggtgctaaat ctgttggaga agttgttata aatacacctt taccagcaat
    16201 acaagaagct gtgtttaatg gaattggtgt aagaataaat acactcccta ttacacctga
    16261 aaaagttttt atggaaatga ataaataatt atttatgaaa atttagacta gttttacatg
    16321 ttaaacaacc agttatgtca tacctgttga aagatattta ataagtagtt attataatat
    16381 tatgaatttt acttataaaa tacaaaatta aataagggga tgatgttttg gctggtaatc
    16441 taaataatat gagagcagta aataatttta gaggagataa gaacatttta gaatgtttag
    16501 tcagctttga gggtcgttca ataagtcaga gaaaagtaag ggtatttttt aaagaaaaac
    16561 aaaatcaaat agaaattgat tttgcagaag aggaaatttc taaattggtt gaaaatgttg
    16621 ttttaaatac atcatatcaa gaaatgttat atgatgaaat agagaaacaa ctggaaattg
    16681 attgtatagg tacttggatg atattatcta aattaaaaga tggtagtaga gttcactgat
    16741 tttaaaataa attattagag cctaatttta aggctctttt ttgctgtttt taattaacaa
    16801 tagaaaactt atctttagtt tgtatataat tttaatatca tatattctat atatataaaa
    16861 ttgaatttgt atgtattata ttgtataatg taaaatgaat tggaaaaata gttcgataaa
    16921 ataatttgtt tttataaaat tactgtttaa gtttatagat tttgtataaa ataaagttat
    16981 gttattaatt tttttagaaa taaaactttt actaggagac agatatgaga aaaaatagta
    17041 ttaatatagc actaactgca gcaattacag caatctatgc agttttaaca ttatcattgg
    17101 gatttataag ttatggacca atacaattta gggtagcaga gattatgatg cttttggcat
    17161 ttttagataa aggatatata gtaggtctta cattaggttg ttttttagca aatgtaatag
    17221 gaccatatgg tgtacctgat ataatttttg gaacattagc cacatttata agtgcaagta
    17281 tgatttatat tactagaaag ttaggtaaac agaataaaag tactttagtt atagcttctt
    17341 tatggccaac tgttataaat tcgattgtgg ttggtctaat gttaaatgta ttctttgggc
    17401 ttccattaat tctatctatg atacaagtag gttttggaga atttgtagta gtgacaattg
    17461 taggagtacc atttttctgc tttttaatga aaaaatataa aaatgtcatt aatattaaat
    17521 tttaaatagt gtatagtaat ttaattaatt gagagtatta ttagtgaaaa gaggtgttta
    17581 tttgtcgaag gtaaaaagat tgactgatgt ttggatatat attaatgata agcaaaagtt
    17641 tacaataaaa gagttgtcag aggaatttaa tctttcagct aaaacaatac aacgatattt
    17701 aaaagaatta aataaaatgg gacttccaat tcaagcagaa caaggtagaa atggaggtta
    17761 tagggtgcta aataatagct atatacctcc tgttatattt acagaaaaag aagttatgat
    17821 tatactattt gcacttaagt cacttcagat ttataattat aagttaatgg aaatagaaat
    17881 taattctata atgagaaaag taagttatga acgtaaaagc agtataaaag taggtataga
    17941 aaatattaaa agatacattg gctttgtagc taatgatact aatgatggag attttaagag
    18001 tagtaatgta actgagtttt ttagagcttc ttcagaatct ctaattttaa atattaagta
    18061 taagtgtggt aatcagattt tggaaaaaaa cgtatgccct ataggtatat atttaaataa
    18121 gggagcatgg ttttcaccag catatgattg taaaagtgat aaaataatat tagttcatat
    18181 agataatata attgatataa aaagaacagg agaaagtaaa aaaatacata taaacttgga
    18241 agaatggtta catgaagtat ataacaattt atatggaaat agttcaacta ctaaaaaatt
    18301 tggtgaaatt atttatctaa atgtattatt aactaaagaa ggtgtttcta aaataaagga
    18361 cagttcttgg aatttagata tggagctaaa tgaagatggt agtggaataa ttagtacatt
    18421 cataaaggtt gaagatatag attgttatgc ttcgatttta ttttttattg gaaataatgc
    18481 taaggttata gagccaaaat ttttgaataa gctactttat gataaggcca atgagttaag
    18541 atatttttat gaagaaaata tggtataata tttagaaatg ttgaaattaa ataattatta
    18601 aggagatata cgttataatg gaaaatttta ataagaatgc taaaataatt ggtattggag
    18661 ctgaaggtat taatataata aatgaagtag aagaaaaaat aaaagcaaat atggatatag
    18721 aaaaaataaa cataaatcaa gagattgaaa aagaatatgt tagaagtctt ttagatggtg
    18781 tagatatatt atttttgata tattcatctg aagataaaca tattagagat attataaaag
    18841 ctgtttcata tatgtcaaac gaaagaagag ttctatctat aggaatggat tgttcagaga
    18901 aagaaaataa agaagattta gagcttggga gagagtttaa aatcaataat gatagtatat
    18961 ttaaatttgt tgatttaatg aatatcatgg tagagtctat ttctgattct tgcatgataa
    19021 atatagatat tactgattta aaagaagcta ttgtaggaga taaaggaatt aagtattctt
    19081 ttgaagagtt tgaagataca aagtcatata gcgagatagc tgacatttta tttgacagga
    19141 tggaatatat tggtgaggaa tttataagta agaaaggaat tgtatttgtt gaaggaagtc
    19201 cagaattttc tataatggaa ttgaatgatt taataagtaa tattcagagc aaggtagaag
    19261 aaagctatga agtaatattt tctttatata taaaggaaaa tttaaatgga aatattagag
    19321 taggcttatt gtataattag tatattttag atattaagga gagtgtatat gtctgaaaat
    19381 ataagaggta cagagtattg gttaatggaa gaattttttt atcaggaaac agacacacca
    19441 cagattttta gagaagaaag cataattgca cttggatttg acataaaaat aaatttaaaa
    19501 aaagtattca gtatggggaa aaaatcagaa aagtatatta atgagaattg taatgataaa
    19561 gattttataa aaaagtttat gtcgattaaa aaaggagatt attttttata taaagcatat
    19621 caaaatatag aagaaaaagt taaatgtaat gtgtctattg gcatagttga agaagatttt
    19681 gaaaatggat atgaattaag tcatatttta gggcatacac taccagtaaa atggatgcat
    19741 aattttgata cagtttcaaa ttgtaaagta tatacaagtg aattttataa attaaataat
    19801 aatgatatta gctcatattt agaaattatt aagtcacaag ataagaaatt attgagaaaa
    19861 agaatagaag aaagtgaaaa taataaatgg tatttaaaaa actattatta taaaaatgta
    19921 gataagtgtg tagatgatga agaattattt attcagccca ttaatctaga acaattagaa
    19981 agcctaaaaa atataaagac agatgattat attttattgt ataatagcga gaaagtaatt
    20041 tgtgaaaatg accatacaat gaagagtcta tttggcgtat gtcaagttat ggaagggttc
    20101 gataaagaga aagtaagtgc tttggaaggt ggatattttt ttcctgttag atggatagag
    20161 tatgaaaagg agaatataga cggaaatgca tgggttatat ttgaaaataa tagtatagtt
    20221 gaaaagtatg taaaaagatt tactaataaa atgccattaa atactatact ttatggacca
    20281 ccaggaactg gtaaaacata caatacaaaa cagatggttt acaatctagt aagtgaaacc
    20341 agtctaagaa acaaatacta tacaggttac ttagattata aaaacaatgt agaattttgt
    20401 acatttcatc aatcatatgg atatgaggaa tttatagagg gtcttaagtc tgatggtgaa
    20461 ggcaatttta agcaagaaga tgggatatta aaggatatat ctatagaagc atgttataat
    20521 gcattgaaat ttgaaaaaaa gatgagcttt gagttggaaa aagatagctt gactttagaa
    20581 actataaaag acaggaaaaa gaaattagta ttagaaaata tagaatatag tgagagtttt
    20641 aattttgaag aatcagaaaa ctatgtttta ataatagatg aaattaatag agggaatgta
    20701 tctaaaatat ttggtgagct aataacatta ttggaagatg ataaaagact tactaaatca
    20761 aatcaaacta ttgtcaaact accatattca aaggaaaaat tttctctacc tccaaatttg
    20821 tatatagttg gaactatgaa cacatcagat aaatcaatag cacttttaga tatagcttta
    20881 agaagaaggt ttaattttga agaaattatg ccagattatg atttattgtc tattgtagat
    20941 ggtatagata ttagaaaaat gctatataca atcaataaaa ggatagagtt tttatatgat
    21001 agagatcatg ttattggaca agcttatcta cttgctgtag aaaatattaa tgatatagta
    21061 gtagtattta gaagtaaaat aataccactt cttcaagagt atttttatta tgattcagaa
    21121 aaagtaggtt tgattttagg aggaattgga agaaatgaaa aagataaata cattgtttat
    21181 aaagaaaaac ttatagcttc tgagttattt aaaaataata atgcctcaat aatggagagt
    21241 aaagttaact attgtataaa acaaaacata tctagtgagg agctaaaaaa tatatatgag
    21301 taaaaatata tatgttaagg aaacctatga atggataagg gtaggtaatg gtgaaaatga
    21361 gcttacagaa attgaatatg aaaaattgct taaatatcta gagaacaata atgatgtatt
    21421 aaaaagtaat ataatagata ttaaatacaa aaaacttaga tttataaact atgtaggcat
    21481 catatgtttt gaaaatgtaa tacttgaaat acttcctaaa ttgtcattaa gtgataatct
    21541 tgtaaaagat agagagatac tattacagat gctttctata tgtaataaaa ttccaattac
    21601 aatgaatgaa aaaataagat tgagtttgaa aaattataat ctcttaaatt tttttgttat
    21661 gtatttcatt gagagtatgc aaacacagat gaaaaaaggt atttattttg aatatataaa
    21721 taaaatagag aacttaaatg ttatgagggg taaaatatta ttaagtacat atgcaaaaga
    21781 aaaaggcatt tctccaatga aaataagatg tgaatatgat gagtatagtg aaaataattt
    21841 cttgaatcaa gttcttaaaa aagcatgtat atctatttta tgtagaataa atgacaattc
    21901 aattcaaggc aagattaaaa aaattttaag ctattttcaa aatgtagatt taatttatag
    21961 tagataatgt atcaaaaatt ggttatgaat agtaaaaata ccagttaagc atattttcat
    22021 gtttctattt ttaacattaa atttccaatc ttcatatgta tatttttaac aaaggtgttt
    22081 acttatttaa aaactctaaa actctttcat taaaatcctg tgcttcttca tatgtagcgt
    22141 gtcccaatcc ctcatagata aatatttcgc tttttttaat cttttctgct aaatgaaaag
    22201 aagcattatt tccaacaatt ttatcattag cacctcctat aattaaggtt ggacatgtta
    22261 ttttatttaa ttcggaaaag gcattatgtt ctatgcaaga ggtcgcttga ataataaatc
    22321 gtttaaaatc ctttggttta cctacttttc ctaaaaaagg aataaataat tggtattttt
    22381 ttaaatatct ttcagaatag gatttctttg ctgtgtcaat cattaaatca ttgtaattct
    22441 gcttcttcgc catatcaatc caactacaaa taacattttg gatagtatca ttttgctttg
    22501 aagaagtaac tgccaacaca agtttctcaa ctaactcagg ataatcaatt gccagatatt
    22561 gagctatcat tccaccttga gaaacaccca ttacttctgc tttcataatt ccaagttttt
    22621 tcattatatc tgcttggtct ttagccatat cccttgtgga atatttttct gtaatttgat
    22681 tttttctact aaatacataa accttataat cttttgcaaa ttgcttatat ctaaaagcaa
    22741 aagcaatcgc ctgtattttt ccatgtaaag gaaataaacc atctcctaat cctggtaaaa
    22801 taattagtgt cttcttacca ctaccaaatt caatataatt cactgtatta cttcctatca
    22861 tcatttgaca actttttgca ttataaaaca tagtctattc ctcgcttttc ctattataat
    22921 tgtctaaata aatctttaaa tttttgaata ccatactcat caattagagg aatatccatt
    22981 ttttttaaca tgaataataa aaaatccaac ctattacata cttcactgta ttcacgttta
    23041 aataatacag ggtcaagtaa aatatcaata ctaaaaacga gcatttcagc taattcctct
    23101 ggatattcac aagaaaattc tttattttca acaccttgtt taattatctt agcaatattg
    23161 ggtgcaacta cattgttgag attacgaact tcctctatta aagcgaatgg gattttttct
    23221 aaccagctac aatgtaccat ttttctacgt gtgtaatcat tcgcactatg aacaaccaat
    23281 tctattattt tttcatttgc tgtaagggtg tcatcagcaa caagatgctc taaaaaatta
    23341 ttcatttgtg agtaaagttc ttttgtgaca cttctcagta tatcttcttt agttttaaag
    23401 tgatgataca ttgcacctct agatagacca gataaattga taatatcttg tgtagatgtt
    23461 gaatcatatc ctttagacga aaatagtgaa aatgctgatt ggataatttt ttctttacta
    23521 tttttacttt tttcttctct attcatattt ccctcctaaa aacagactgt ctgtttgttt
    23581 tttattatac attttaatat ttattatgtc aagaattaac tgactttcaa tttcttcata
    23641 gttcagatgg aacgaaaagc attccacatc aaacttttaa aaagttgtat tacctcaaca
    23701 aggtctaaaa gatacatctc tatgctgtac tcgtattcct tataatagag atgtattgtt
    23761 ttcaaagata atcaagattt tgctgtgttt ttcatacaaa ataaaaagga tacctcatta
    23821 gtgctataac acctaagata tccaattaat attttcttaa ctttttctaa tttacataaa
    23881 tatagtctac tattttaaaa ctgctcctgt atttgctgat gttaccagtt tagcatatct
    23941 acttaagtat ccatgcttta ttttcggttc taaaggttta aattttaatt ttctattttc
    24001 tatttcaact tcatctactt ttaactctaa ttttttgtct ggtatgttta tagaaattat
    24061 atctccttct tcaactaacc cgattaaacc accttccata gcttctggag aaatatggcc
    24121 tatagatgct cctctagttg ctcctgaaaa acgaccatca gtaagaagtg ctacatgctt
    24181 atcaagtccc attcctgcaa ctgctgatgt aggagatagc atttctttca ttcctggacc
    24241 accctttgga ccttcatatc ttataactat aacatcacct ttgtttattt ttttaccaaa
    24301 aatagcattt acagcttctt cttctgaatt aaaaactctt gctggtcctt catgaactaa
    24361 catttcttct gcaactgctg acttttttac aacagctcca tttagagcaa gatttccttt
    24421 caatattgca agcccacctt ggttactata tggattcttt aatgtatgta ttacttcttc
    24481 attttctatt tcacaatttc ttatattttc ccctatagtc ttgcctgtta cggttttgca
    24541 atctaaattt attccattta tctttgaaag ttcgttcatt atagctggta ttcctcctgc
    24601 catatgtaaa tcttcaatat gatgttttcc acttggactt aattttgtta aacaaggagt
    24661 tttttcactt atttcatcaa aaaaatttaa gttaagctct attcctgatt cataagctat
    24721 tgcaggtaag tgaagtactg tatttgtaga accagccatt gccatatcca cagctatagc
    24781 atttttaaaa gcatctattg ttaaaatatc tctaggtttt atgtcgttct taagtaactc
    24841 cataacatac atacctgcat attttgctat cctttttctt tctccagaat gtgacgcagc
    24901 agtaccatta tatggtatac ccatgcctaa agcttctgtt aaacaattca tgctatttgc
    24961 tgtgaaaaga ccagaacatg aaccacatcc aggacaagag ttcatggcta acgcttctaa
    25021 ttcttcttca cttactgttc catctttaca tgctccaaca ccctccattg cagagttaaa
    25081 atcatatact tttccatttt ttttacctgg aagcataggc cctccactca caacaatact
    25141 tggtatatta agtcttgcag cagccattaa catacctggc actatcttgt cacaattagg
    25201 tataagtacc aaagcatcaa aaccatgtgc catagccata gcttctattg aatctgctat
    25261 taattctctt gaagccaggg aataattcat tccaacatgc cccatagcta taccatcaca
    25321 tacccctata gcaggaaatt ctaatggcaa accaccactc attcttactc cattttttgc
    25381 agcttctgct atttcatcaa gatgcagatg accaggaatc acctcatttt gtgcatttac
    25441 tatacctatt aatggtcttt caatttcttc tttagtaaga cccattccat acattaacgc
    25501 tctctttgga gctccttcta ttcctttttt tatatcactt ctcataatat tacctctttc
    25561 ttactttttt aaattttcat aatattatta taatatattt ttctattaat taattacgaa
    25621 aattgtaaaa aaatattagc atatactaat gaaaatttat tacgattttt tatcaatatc
    25681 ttacacaatt gtattatata atattatctt ttcaatatat tttataaact aatatatttt
    25741 acaaattgtt gagtaatatt ttatgatata aatcagaaga ggcacttcta taatagaaag
    25801 tgctcaacta tgaataagat taataatata tttgccttag atatatagac ttttataaat
    25861 attaaagatt aatcaaatct gatgtttgaa actttatccc aattaatctt ccttgaatag
    25921 tcttctggat gtgataatct aactatatga gttgaattat catagctgta ataaattgta
    25981 gtagtaccat caactggatt ctttttgtat ccttgataca cagcactatt tggtactttc
    26041 ttttcaacaa agctatatgc agatgaagta tcaatagttt ctattttatt aggaaatata
    26101 aacatataaa aagctactac tataaaaata catatgcatg taatactata ccatttaatc
    26161 catttcataa aattcctcct actttaccaa aatatactat tattatttcc atatatttat
    26221 aatatttatg catacgataa aatttttata tccctaacta tataattgta gaaactttga
    26281 ttatatatat tttttaatct taataatata tttttataaa ttaataaatt tttaagattt
    26341 tattaaaaga tttttaaaac ttacagttta atataaagat agtacttata aaactaaaaa
    26401 cataaatttg aaaggggaca aaataaaatg atatggacat tttattcatt tatttgcgtt
    26461 atattaccat gcttaatata ccaaatagtc gttataaaac gaaaaaattt gaaagttgaa
    26521 aagaatgtaa tgatacattt agtatgggta tatatttttt tattatatat ctatctagca
    26581 cttagtaaag ctggaattgg tagcatatgg gatataggaa ggtatagtgg gctttttaga
    26641 attgatgaaa taaatctaat accttttgac tcagttggca tcttaacata tattttaaat
    26701 ataattatgt ttatgccttt aggattttta ctacctttaa tttggaaaaa ttttagaaat
    26761 attatcaatg tttcattaac tggattaggt ttttcattag caattgaact ttgtcaattg
    26821 tttaacttaa gagctacaga tattgatgat ttaatgatga acacattagg tgctgtttta
    26881 ggatatttta tatgggtagg tgtaaataat ttatttaatc ttataaagaa aaaagatatt
    26941 ttcccatcta tatataaaaa tattattcaa gatgaaattg ctattacaat tgatgatgac
    27001 ataagcgaaa aaattacctc tctttacaaa aatgaagcta ttatatattt aatacttgct
    27061 gttttaggag aatttttatt gtttaattgg tccattatac cttattaaat aatttattga
    27121 taaaacaagt gtacttcgat atttacaaat atgtaaagcc ctctttcata ccacaaaaga
    27181 aagtgggctt tagttattaa attaaaatgc acactcacta tttagctggc atctgaaata
    27241 ttttattaac attgtatctg actttatttg atgttatata atcatatttt gttccatttt
    27301 caatgaagtt ttgtatattg tccaacactt gtatagctct tgtattattt tcataatctc
    27361 ctatttttac agtatcaatt ttactttcaa atactgcata aacttgacta ccatctattt
    27421 taatttggtt tatctgcatt aaattagttt tatcttgact tctaattatt atcatatcaa
    27481 ttcctccatt tacttaattc attttaattt ctaagaaata atattttata attgatttat
    27541 agattattta aatttttaaa cttag
//
LOCUS       DAJMZY010000047        27358 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.047, whole genome shotgun sequence.
ACCESSION   DAJMZY010000047 DAJMZY010000000
VERSION     DAJMZY010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 27358)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27358)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27358
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.047"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            <1..1620
                     /locus_tag="OE968_001976"
     CDS             <1..1620
                     /locus_tag="OE968_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HCP7219255.1"
                     /translation="DSDIISKIYIYLTLSAISIRKYDKVNNFYFSAKKIIRQNHLNEL
                     LVLLNMSLCVEISALYQTKTDVIALVEEVSFFKTLKNKALVSRANYIFGRVYLYLFNN
                     FIKSMEYLIECLKLAQENNLYSIEAFCKCIISLCYLESGNNVEAIKYINNVLDVAHSN
                     NSISVTERVSIKIDLIWAYLKEDMNKEAEVILLKTIKLMKVVEGVYKDYLYSFIFLYS
                     AEIELKKDNCSFEKVNTYLILSKNIYKSFGDVFIYNSKLDYIYKLYGDLYIKFGNIDE
                     GISCYIKGLNLVKKSSLNLRKISIFYGLIANGYELKKDFKLAIEYYKSMDWYSDRWEK
                     NNSYKTSQAIHKQYELRQKQESLRLLVDDNKKLENDILKDGLTKLYNRRYLEQQLDLF
                     NETRDKNMVAILVDIDCFKSYNDNYGHLAGDKVIVKVTDIIRSVFIDITEHIIRYGGE
                     EILILVDSIESIGVEEIDNIELYIKRVFKLLEFEGIEHIYSKIKNYITISAGVSIKRC
                     RSRKDVEILIEDADKNLYKSKKAGRNQYIII"
     gene            1628..3628
                     /locus_tag="OE968_001977"
     CDS             1628..3628
                     /locus_tag="OE968_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HCP7219256.1"
                     /translation="MILLRKKIGIIASDIELKERIEELYREDVENGTIIIDILNLDLM
                     ENQGRILVEKGAQAIIGRGGGYSLVIDTVNVPVIPMNMKSTDLLRAIEIAKKYSKKVV
                     LILGDNEVSFDYVGWRNVISTEITEEWFESKYEIRSKVVKYIDQKDEIVIVGGGLACS
                     FARQYGIDSVFATASDESIREAVEYCKKLLDTLGEEKFNNEVLRNILDGIKDGVIAID
                     SNGSIILYNESAKNMLKVERKCALNKYILDVFPKMEWMLDCLHEKEDVEDRKIRNINN
                     LIVNTRTTLIKVDNSTYGVLGIIQDITKLQNLERKIRFDLNQKGLYARYTFDDFLFKD
                     KLTKEFIEEAKKIGKSDYTTLLYGESGSGKEIIAHSIHNISKRKDRPFVAINCATIAE
                     NLLESELFGYEEGAFTGARKGGKRGLFELAHGGTLFLDEINSLSFNIQTKLLRVIEER
                     QIMRIGSDYIIPLDIRIIAATNESLTEKIVMGTFRADLFYRLSSLEINIPPLRDRRED
                     IIPLFNNFVNEVLKDDGLNGINSIDENFVLTKDEMDKLYNYSWPGNVRELKTIAQKYV
                     VTGKIKLRQDRDFKTKKLLPNSEVDKFNSETTASVEVQDESINISKINDGKISIDIKE
                     VNKYVEEKIISMLFAQGLSKNEVAQVLGISRTSLWKKYNKNI"
     gene            3890..5149
                     /locus_tag="OE968_001978"
     CDS             3890..5149
                     /locus_tag="OE968_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HCP7219257.1"
                     /translation="MSQSMVGKHAMWPKENDVIFSISGRAQAAEKAFGMDNVINATIG
                     ALMDDSGKLITMKTVYEEYKALDNCEIGAYAALEGQPDYLEAVKKVFFRDYLPEGHIR
                     VLASPGGSGAIKLAVWNYTNEGDEVLTSDWFWSPYVSIAEEANRKVVNYQLFDENRRF
                     NFESFKEKFVNIAEKQGRVFTIINTPAHNPTGYSVADDEWDKILDLSKEVAKDKDKKI
                     IFFVDSAYIDFAGDDDVCRKFFKKFSNLPENVLVLVGFSMSKGFTAYGMRMGAIICIS
                     SSEDVAEEFHYSCVHSCRANWSNCNRSAMAVLSNIVNDPKKFKEYEDEKEIYKNMLTR
                     RADVFVKEAERVGLEILPYIAGFFVSIPCDNPKEVCEELTKHNLFAVPLKMGLRFAVC
                     AVSEDKCKKAPSIIKEALESLEVKINN"
     gene            5210..6997
                     /gene="iorA"
                     /locus_tag="OE968_001979"
     CDS             5210..6997
                     /gene="iorA"
                     /locus_tag="OE968_001979"
                     /EC_number="1.2.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indolepyruvate ferredoxin oxidoreductase subunit
                     alpha"
                     /protein_id="HCP7219258.1"
                     /translation="MKQLMTGNEAIARGAYEAGVKYASAYPGTPSTEILENIATYKDA
                     IVAEWAPNEKVALEAAIGGSIAGARTMASMKHVGLNVAADPIFTYAYTGVNGGMVLIT
                     ADEPGMHSSQNEQDNRMYAKFAKIPLFEPSTSQEAKDMIKEAFEVSEKYDTPVLYRVT
                     TRLCHSKGLVECYDREEVEIKEYVKNAKKMVTVPANAQIRRGVVEERMEILKKFSNET
                     DLNYYEINDTKIGVIASGMCCNFAKEVFGKNASYMKLGFTNPLPYEKIKEFAEKVDKI
                     YVIEENDPFIEEQIKAYGIDCIGKDVIPPYGEMTPDVLRKAIFGKTNDTIEYKSELVT
                     PRPPSFCAGCPHRGFFYELGKRKNLIVGGDIGCYTLGFAPPYNGIDYVVCMGSAFGTA
                     HGAQKVLNMKDDNEKRLVGVLGDSTFFHTGINGLLDVVYNRGNSISVILDNRITGMTG
                     HQENPGSGYTLQGAKTKEVDIEGLVKACGIEHVRVINPNNLKEVNEALDWALAIEDEP
                     SVIITRWPCVLKKFSKEDIEEFNNPFKTKCKVDHDKCIGCKLCLKTGCPALSFDKENK
                     LSNIDRNQCVGCGVCAQVCPKQAIVKEEK"
     gene            6999..7574
                     /locus_tag="OE968_001980"
     CDS             6999..7574
                     /locus_tag="OE968_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indolepyruvate oxidoreductase subunit beta"
                     /protein_id="HCP7219259.1"
                     /translation="MTKSILLVGVGGQGTILASKLLTMGLMEAGYDVKMSEIHGMSQR
                     GGSVSSQVRYGDCVHSPVIEIGGADILVSFEKMEALRWFNYLKPEGKALVNNHRIDSM
                     TVLIGGAEYQESDIDAELSRLNAKVINAADKAEELGNSKIMNVILLGCLVKSMQLESI
                     DWEKIISENVKPKFVELNIKAFHEGMEMVSK"
     gene            7627..8697
                     /gene="buk"
                     /locus_tag="OE968_001981"
     CDS             7627..8697
                     /gene="buk"
                     /locus_tag="OE968_001981"
                     /EC_number="2.7.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="butyrate kinase"
                     /protein_id="HCP7219260.1"
                     /translation="MTYRILAINPGSTSTKIAVYDGEEQILVKTIDHPAEEIAKYNTI
                     QDQFEMRKEAVLNILKENSIDLKSLSAIVGRGGVLPPVKSGAYLVNEEMIDVLRHRPV
                     LEHASNLGAVVAHAISEPLGINSYIYDSVAVDELIDVARISGLCGMDRSSAGHALNTR
                     AMALKYAKDKGKDYKSLNLIVAHIGGGVSIYLHEKGRMVDMLSDDEGPFSPERSGRVP
                     ATKLVAACYSGQYSEREMTKKIRGKGGIVSYLNTVDAREVEKMIAEGNEEAKIIYEAM
                     AYQLAKGIGELATVVDGKVDAIIITGGIAYSEMFTSMVKKKVEFIAPVEIMAGENELE
                     SLAFGTLRVLNGEEEARIYSEN"
     gene            8915..9616
                     /locus_tag="OE968_001982"
     CDS             8915..9616
                     /locus_tag="OE968_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219261.1"
                     /translation="MGKISLKSMIRLFSGFFIFAISSVLMINAHVGLMPWDVLHQGLS
                     IKLGITIGQASIMVGVVIVILDAVFGENIGWGTLLNMTFIGIFIDLVIFSGVIPHASN
                     TYIGVFMVVIGIILAAIASFLYLGVCLGSGPRDGLMIALQKKTNKSVRLVRTILEILA
                     LVVGWLLGGSVGIGTLVSALGLGYVLQIVFRIFKFDTKLLKHRFIIDDIREWKEKKSN
                     EHKCKSSIVIKNEQN"
     gene            9676..10182
                     /locus_tag="OE968_001983"
     CDS             9676..10182
                     /locus_tag="OE968_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HCP7219262.1"
                     /translation="MELWDLYNADGIKTGNVIKRGNSIEEGYYHLAVEVWILNSNSQI
                     LIQKRSKSKKTLPNMWGMTTGCIVSGEDSLEGAIREAKEEIGIDITKDEMKVFRSMIH
                     EDTLWDVYLVKKEYDISKAILQEEEVSDIKWVSTDEIRQLLKEGLFFEYPEIYELLYE
                     IDNNKLNI"
     gene            10357..11379
                     /locus_tag="OE968_001984"
     CDS             10357..11379
                     /locus_tag="OE968_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HCP7219263.1"
                     /translation="MEDNKGLARDSSKYKIVSISVVVIILITFWYMLNMVLLTFIMTF
                     IFYNLLVATRKRIKKFSSLNIPDSLIIIVLYALFAILLVLISYAVVPIIIVQLTELSR
                     VFSDFDVNQFAQSLGPKLYPIVSKLDFNKYISQAGLLIASTATKVGSFGVNILLAFLL
                     SLLLLLEKNEIKNFGDKLSDSKISFIYNSLVFFGKSFVKNFGEVMKVQVMIAFINSVV
                     SMIFLGFMGFPQIWALGFMIFVLGLIPVAGVIVSLIPLTVIAFNTGGITKVFGVLLMI
                     CIVHAVETYILNPKLMSNRTKLPVCFVFIILLVGEHYLGVWGLLIGVPIFMFLMDILG
                     VKFTSR"
     gene            complement(11526..11834)
                     /locus_tag="OE968_001985"
     CDS             complement(11526..11834)
                     /locus_tag="OE968_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1540 domain-containing protein"
                     /protein_id="HCP7219264.1"
                     /translation="MKNNNLNCAATNCAYNTSGYCYAGSIKVDGMQATTTENTYCASF
                     EDKYTSGITSRSNETNQVDTDNIHCEAVKCKYNKNELCKAEKVHINERNASCETFEMK
                     "
     gene            complement(11894..12322)
                     /locus_tag="OE968_001986"
     CDS             complement(11894..12322)
                     /locus_tag="OE968_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219265.1"
                     /translation="MNNKLHELEKNLPEISCSFCTHLSFKGPSLDYRYDIRCVISDTK
                     PDFRGCCEYFEPEYTELNTGDLDNLYINFLETCLKVNYNDYINSMYWKLFKERTLLEN
                     NFKCSICGSTENVDVYHVNKNLGRETSKDVVVKCDKCNCK"
     gene            complement(12545..14002)
                     /locus_tag="OE968_001987"
     CDS             complement(12545..14002)
                     /locus_tag="OE968_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon starvation protein A"
                     /protein_id="HCP7219266.1"
                     /translation="MTTFLIGLAILLIGGALYGAYCEKVFGPDDRKTPALAQSDGVDY
                     VPMKKWKNSLIELLNIAGTGPILGPIQGILFGPIAFILIPIGCVFGGALHDYMSGMIS
                     IREKGAQMPSLISRFLGNKVFQVYNIFLCLLMLLVGAVFIYTPGDLVVTQILNMKSTI
                     NNPVVWIVYGLIFLYYLCATLFPIDKIIGKVYPIFGAILLLSAAGVGIGIFTQGYDLA
                     NLSLANWKGIHPDGIPLIPTFFVTVACGIVSGFHSTQATLIARSVSNEKEGKTTFYNM
                     MILEGLIAMIWAAAAMGIYNKGIPKELVGSPDVIGLVARDLLGSIGGIIAIIGVIVLP
                     ITSGDTALRSLRLMLADYFHYDQKEKKHRVILSICIFIPVIAILIFAKLSASGFNILW
                     RYFSWSNQTIAIFAFAMITVYLIIKEKNYIISLIPGMFYSFVIFSYIFNAQIGFNLNI
                     NISYVLAAIFTVLYAILTVRSGRKLKSKADTKLAD"
     gene            14420..15334
                     /gene="nadA"
                     /locus_tag="OE968_001988"
     CDS             14420..15334
                     /gene="nadA"
                     /locus_tag="OE968_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinolinate synthase NadA"
                     /protein_id="HCP7219267.1"
                     /translation="MDKDLTYQIKELKKEKNAIILAHFYQPPEIQELADAVGDSYYLS
                     EIARDCKEEVVVFCGVRFMGESAKILSPEKTVLMPVSNAGCAMADMVDEEGVIKLKQQ
                     YPNALVVCYINSTAKVKAHCDVSVTSSSAIKILENIDNKEIIFLPDKNLGGYIAEQFP
                     DKNFIFWDGYCKYHNNIRAEEIIELKDKYKNAEVLVHPECKKEIRDLGDYVGSTSGII
                     KYATNSKNKDFIIATEEGILHELKKNNPNKNFYIPGGKILCTDMKKTTLENLYSTLKN
                     MENEVIVEDEIMEKALNSLLNMHKLAEG"
     gene            15347..16648
                     /locus_tag="OE968_001989"
     CDS             15347..16648
                     /locus_tag="OE968_001989"
                     /EC_number="1.4.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-aspartate oxidase"
                     /protein_id="HCP7219268.1"
                     /translation="MNLEQDVLIVGSGVSGLYCALNLDKSLNVLVVSKSTIENNNTYL
                     AQGGISTARNIDDIESFVEDTMKAGQYKNRVEAVQVLADESIENVGQIVEYGMPLDKE
                     NGEIDYTREGAHSVNRIVHSKDNTGEVVFKTLLKEAKTRENITLIEDAYLLDILKDGN
                     KCIGARIFKSKKEIHVFSKIVVLATGGIGGLFKNSTNQRHLTGDGIAIALRNNIKIEN
                     LEYIQIHPTAFYEENNEGRRMLISESLRGEGAKLLNKNKERFVDELLPRDVVSKAIFE
                     QMEKDKLPYVYLDATHLDSEYLINRFSFIYNECLARGTDITKECIKVSPAQHYFMGGI
                     HVDLDSKTSMENLYAVGEISCTGVHGANRLASNSLLEGLVFSKRAAKNINSVIDNVKV
                     KFIDVPDMDIDIEQVKKENKILVIKEIERTSEDFGDELFDY"
     gene            16629..17465
                     /gene="nadC"
                     /locus_tag="OE968_001990"
     CDS             16629..17465
                     /gene="nadC"
                     /locus_tag="OE968_001990"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HCP7219269.1"
                     /translation="MNYLIIDRMIQDALIEDVPSEDITTNSIVDENSKSTVDLICKQD
                     GIIAGLGVFKRVFEILGDVDVKLYKNDGDRVKNREKIAVLTGSTRNLLVGERVALNYL
                     QRMSGIATITSRYVEKLEGTNTKLLDSRKTIPNLRILDKYSVKVGGGCNHRFNLSDGI
                     LLKDNHIGAAGSVKKAVELARKNTSFVRKIEVEVETLDMVKEAIEANADIIMLDNMSL
                     EMAKQAVDIINGRAIVEFSGNVNLDTIEDIGKIGVDVVSVGALTHSVKALDISMKNLR
                     NI"
     gene            17721..18053
                     /locus_tag="OE968_001991"
     CDS             17721..18053
                     /locus_tag="OE968_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE family protein"
                     /protein_id="HCP7219270.1"
                     /translation="MKVAYIFSSTNTHKILDKMIIPQLEQGTHGVDVLGMFFFMDNTL
                     FLSKGNPVGERLSKLHEKTDMIIMACDQCAIERGIENNLVDGATIGCFPNLYACLGSA
                     GVDQVITL"
     gene            18215..18400
                     /locus_tag="OE968_001992"
     CDS             18215..18400
                     /locus_tag="OE968_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219271.1"
                     /translation="MSEKYADKLEIKLYQAGKDFSYIKKYGIITKGTLIINQKKKYDR
                     LNKDTIERAIVEAINNN"
     gene            18427..19512
                     /locus_tag="OE968_001993"
     CDS             18427..19512
                     /locus_tag="OE968_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HCP7219272.1"
                     /translation="MNILEIVLNGVKDTIVASIVTLNGASGWLMISFILAGVLHNVLT
                     PRRFQKQLGNKKFSSLIKSTISGMFLPICSCGVIPLGISMYYSGAYLGPVLAFMTSTP
                     IINPIAVVLCLGLLGPKVTIIYLIAGFLVPFLVGFLGNCFGKEELSLHNDSEEEVIEL
                     EEEKRSFMENMIDGLKWSFGELALTISKYVVMGMVFAGFITTIFPNSIIQKYLGNPGL
                     LSLGSIAILACVMYVCAVGHIPFIAALVASGASPGIAITFLIAGAATNLPELISMFKL
                     IGKRTVIIYSVTLTLSSIIIGYITNLLLVNNNSVNLDATNSSIQLANKLMLNIPDSFE
                     YVCTILIILFAFKSIIPKMKEVIGNHA"
     gene            19505..19963
                     /locus_tag="OE968_001994"
     CDS             19505..19963
                     /locus_tag="OE968_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219273.1"
                     /translation="MLKKIVIISCIVVVLIILSKIVDDNIKEDASIPNVNKETLEYFR
                     KNYKEDIITCAEEDLNNDGKKDLVVIYKKSNNSNEMVVVVSDKNSHYITKPIPAPIEN
                     QTITFKNIDDKAPIEVIVSGSKNGNVGYAIYRVEGKKFVDLFGEDMDKCC"
     gene            19998..21089
                     /locus_tag="OE968_001995"
     CDS             19998..21089
                     /locus_tag="OE968_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HCP7219274.1"
                     /translation="MKLSKKIQALILFGVMGTSILTGCSSKPKEKEEAKTGKDDYTIT
                     VGYYNCDHMTAGPVAESAGIYKDLGLNVKTVGNGKVPEAMAAGKMDAGYIGTKGLVGA
                     IPKGSPITIAANNHTGGSEYLIVSKDIKEPKDLIGKKIATDMSDFLWTSDYGPETGLP
                     TDPSKYEVVNMDSDKDKYLALKTGKIQAFTSCDPWGSVAENDGAGKIIASTQYKEKAN
                     GKEYNCCSFSLNKNFIKEHPDLAKKLVLAHTKAIEYIYTNPAEAAKIFAKYYNVEEEV
                     ALRTIYKKTVGEGRTLTWKVTGEEYKNNLQMYKDLKALDDIPKYEDTIDTSLLDSCGA
                     DDFDKFIKEKVNPEFPEGMSYEDWKAKVL"
     gene            21094..21318
                     /locus_tag="OE968_001996"
     CDS             21094..21318
                     /locus_tag="OE968_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219275.1"
                     /translation="MENMKNIIILFIIILGSIFIIFFNFEDKEEIKGKLRIGVSDDTS
                     GFVINYMVNRDYFENIKVSDIMDIFTINDC"
     gene            21328..21891
                     /locus_tag="OE968_001997"
     CDS             21328..21891
                     /locus_tag="OE968_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219276.1"
                     /translation="MQWALSSEEIDIAIICKDAAKQYVNVNSGFEIVGTVVQNSDIFL
                     LSDNNPEKIGVIQNRDYQSELVKKYYKNVEVAPLLGTALAYGLESNLVDGVVIDCIKS
                     IGLEGKRKSTTKLGDYDTYVLVVSKEFKKSKAYSDFITLYNKSVDALKNKATFKKALK
                     EYRNIRNIDMEEISNWKLKFLKIKAID"
     gene            21852..22481
                     /locus_tag="OE968_001998"
     CDS             21852..22481
                     /locus_tag="OE968_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCP7219277.1"
                     /translation="MEIKISKDKSDRLTKKKTDGSMDILYKIILLVIIFLVWHFAAKD
                     IGSSLLLPMPVDVIKGFFFCVTDAETVTNLFITLQRVLKGFMYALLFGLPIGFIMGFS
                     KTFERVLSPVVDSVRQVPIMAWVPLTIVWFGIGDGPTIFLIAFSGVFPIILNTIQGVR
                     AISKDYYNAARSMGASPIVIFTNVIVPASLPDILTGSRIAISTGWMSVI"
     gene            22658..23410
                     /locus_tag="OE968_001999"
     CDS             22658..23410
                     /locus_tag="OE968_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCP7219278.1"
                     /translation="MKLSVRDINKTFVNNRVHTKVLEDISMDIDDGQFVCLLGPSGCG
                     KTTLLTIIGGFQKSERGDVFINDKRVKKPGIDRAFIFQNYALFPWKTIRGNVLFPMKQ
                     QKIPKEKREEMLEELLVMSDLKGKEKLFPHQLSGGMKQRVAMIRALACNPEVLLMDEP
                     LGAVDFQMRQNLQEELERIWIKKKITALMVTHDVDEAVYMSDRVIVMSRDKGRIIDDI
                     NIDIPRPRIRGSQKYEEYKNKLTDTLSKCYEV"
     gene            23423..23908
                     /locus_tag="OE968_002000"
     CDS             23423..23908
                     /locus_tag="OE968_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219279.1"
                     /translation="MSQIEKYNSLDNTQQKIRISIMDMIIDKGSSVTLQEVTEYISKK
                     LNIEKEYIERTLQYFIYKNIMVVDGNSINFIYPVSALPTNHKVTLRDNRSFSAMCAID
                     AIGTSCTFNQDIKINSICSATGKEIEVIIKNEKIEYVNNPNLRVLHINLDKHLNWAAS
                     C"
     gene            23915..24064
                     /locus_tag="OE968_002001"
     CDS             23915..24064
                     /locus_tag="OE968_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219280.1"
                     /translation="MNFFWTKSDFDAWTNEAGLSNDEDIYCLDINEAIVESYKIFKLK
                     QKVLS"
     gene            complement(24201..25022)
                     /gene="yidA"
                     /locus_tag="OE968_002002"
     CDS             complement(24201..25022)
                     /gene="yidA"
                     /locus_tag="OE968_002002"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HCP7219281.1"
                     /translation="MYKLIALDIDGTILNTQKRITPEVFESIQEAKRAGAKVVITTGR
                     PLPGVKELLNQLNLTDEGDYVICFNGAIIQEVKSEKIIHDVEMSLDDFDFIYNNVCKK
                     YKTKIHINTMTNLITPNETPGKYTLHEAKLNNIEVKYIQKDKIDESIKICKIMIVDEP
                     ERLEEIIQQLPKNLFNKYTIVRSAPFYLEFLGKTTNKGTALKTLCTNLNIPIENAIAV
                     GDEENDQHMIKYAGLGVAMGNARNSIKEIADYVTDTNNENGVAKVINKYILNKAI"
     gene            25515..27209
                     /locus_tag="OE968_002003"
     CDS             25515..27209
                     /locus_tag="OE968_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HCP7219282.1"
                     /translation="MKFSEFKYERPNYNSMKKEFLSCVEDINNSRNYKEQQKNIHKIN
                     LLRNKIETLSNIASIRYSTDTFNKFYKEEKNYWDEYMPLYEELNSYFYNAIVNSKFKY
                     DLIKEFGEQFFTIVEYSLKSFSKEIISELQEENKLCSEYTRLLASAEIMFDGKIRNLS
                     GMGKFMYSKNRKTRELANKAYYNFFEENETKFDDIFDKLVKLRDKMSKKLGFEDFVEL
                     GYVRMMRSDYREYMIKNVRKQVLKYVVPMANELYEKQAKRIGLEYLSYIDEGVEFLTG
                     NASLKGDSRYIIKNGKRMYSELSKETNEFFDFMLENELMDLETKKGKGAGGYCTYIPD
                     YKSPFIFSNFNQTADDIDVLTHEAGHAFQLYMSRWIDMPEINFPTLDSCEIHSMSMEF
                     ITWPWMDLFFKEDTDKYKFTHLSSSIKFIPYGVIVDEFQHYIYKNPNVDKSKRKEIWR
                     FLEKKYLPHRKYGDNSFLERGCWWFKQGHIFKNPFYYIDYVLAQICALQFWKKMIQDR
                     DAGWKDYINICKVGGTKSFLDIVSMGNLYSPFDDGCIESIIGDVKSWFDEINDSKL"
BASE COUNT        10681 a         2878 c         4891 g         8908 t
ORIGIN      
        1 gattcagata taatatctaa aatttatatt tatcttactt tatcagctat ttctataaga
       61 aaatatgata aggtaaataa tttttatttc tcagcaaaaa aaattataag acaaaatcat
      121 ttaaatgagt tgttggtatt gttaaatatg agtttatgtg tagaaataag tgctttatat
      181 cagaccaaaa cggatgtaat agctttagta gaagaagtgt ctttttttaa aactttaaaa
      241 aataaagctc ttgtaagtag ggcaaattat atatttggga gagtttatct atatttattt
      301 aataacttta taaaaagtat ggaatactta attgaatgtc taaaattggc tcaagaaaat
      361 aatttatact ctatagaggc tttttgtaaa tgtataataa gtttgtgtta tttagagagt
      421 ggaaataatg tagaagctat aaaatacata aataatgtat tagatgttgc acacagtaat
      481 aactcaatat cagtaactga aagagtgtct ataaaaatag accttatatg ggcatattta
      541 aaagaagata tgaataaaga agcagaagtt attttattaa agactataaa attaatgaaa
      601 gttgttgaag gtgtatataa ggattattta tattcattta tatttttata ttcagctgaa
      661 attgagttaa agaaagataa ttgtagtttt gaaaaggtaa acacctattt aattttatca
      721 aaaaatatat ataaaagttt tggagatgtt tttatatata attctaaact agattacata
      781 tataagttgt atggagattt atatataaaa tttggtaata tagatgaagg tataagttgt
      841 tatataaaag gtttaaattt agttaaaaag agttcattga atcttagaaa aatatctata
      901 ttttatgggc taatagcaaa tggatatgag ctaaaaaaag attttaaact ggcaatagaa
      961 tattataaaa gtatggattg gtattctgat aggtgggaaa aaaataattc ctataaaaca
     1021 tctcaagcaa ttcacaaaca atatgaactc agacaaaaac aagagagttt aagattacta
     1081 gtggatgata ataagaaatt agaaaatgat attttaaaag atggacttac taaactatat
     1141 aatagaagat atctggaaca gcagttggat ttatttaatg aaaccagaga caaaaatatg
     1201 gtcgcaatac tggtcgatat agattgtttt aaaagttata atgataatta tggtcatcta
     1261 gcaggagata aagttatagt taaggtaact gatattataa gaagtgtatt tatagatatt
     1321 accgaacaca taatcagata tgggggagaa gaaattttaa tattagtaga ttctatagaa
     1381 tcaatcggtg ttgaagagat tgataatata gaattatata ttaaaagagt tttcaaactt
     1441 cttgaatttg agggtattga acatatatat tctaaaataa aaaactatat aactataagt
     1501 gctggagtaa gtataaaaag atgtcgtagt agaaaagatg ttgaaatatt aattgaagat
     1561 gcagataaga acctatataa atcaaaaaaa gcaggtagaa atcaatacat tataatttaa
     1621 aattgaggtg attttgttgc gaaaaaaaat aggaattata gcctctgata ttgaattaaa
     1681 agaaagaata gaagaattat atagagaaga tgtagaaaat ggaactataa taatcgacat
     1741 acttaaccta gacttaatgg aaaatcaagg tcgtatactt gttgaaaaag gtgcccaagc
     1801 tataattggt agaggtggag gttatagttt agtaatagat acagtaaatg tacctgttat
     1861 accaatgaat atgaagtcaa ctgacctttt aagagcaata gaaatagcaa agaaatattc
     1921 taaaaaagta gtattgattc ttggagacaa tgaagtttct tttgactatg ttggctggag
     1981 aaatgtcata agtactgaaa taactgaaga atggtttgaa tctaagtatg agataagaag
     2041 taaagttgta aaatatatag accaaaaaga tgaaattgta atcgtaggag gaggtttggc
     2101 atgttctttt gcaaggcaat atggaattga tagtgtattt gcaactgcta gtgatgaatc
     2161 tataagagaa gctgtagaat attgtaaaaa attattagat acattaggtg aagaaaagtt
     2221 taataatgaa gtgttacgaa atatacttga tggtataaaa gatggagtaa ttgctataga
     2281 tagtaatggc agtataattt tgtacaatga aagtgcaaaa aacatgctta aagtagagag
     2341 aaaatgtgca cttaataaat acatcttaga tgtatttcct aaaatggagt ggatgttaga
     2401 ttgtttacat gaaaaagagg acgtagaaga tagaaagata agaaatataa ataatctaat
     2461 tgttaatact aggacaacat tgataaaagt tgataatagt acttatggag ttttaggaat
     2521 aatacaagat ataaccaagc tacaaaactt agaaagaaaa ataagatttg acttgaatca
     2581 aaaaggtctc tatgctagat atacttttga tgatttttta tttaaagata aattaactaa
     2641 agaatttatt gaagaagcta aaaaaattgg aaaaagtgat tatacaactt tactttatgg
     2701 ggaaagtggg tctggtaaag aaattatagc tcatagtata cacaatataa gtaaaagaaa
     2761 agataggcct tttgttgcta taaattgtgc tactatagca gaaaatttac ttgaaagtga
     2821 actttttggc tatgaagaag gtgcatttac tggtgctaga aagggtggaa aaagagggct
     2881 atttgaactt gctcatggag ggactctttt tttagatgaa ataaatagtc tatcctttaa
     2941 tattcagaca aaactattaa gagtaataga ggaacgtcaa ataatgagaa ttggttctga
     3001 ttatataata cctctggata taaggattat agcagcaacg aacgaatctt taaccgaaaa
     3061 aatagttatg ggtacattta gagcagactt attttataga ttgagtagtt tagagataaa
     3121 tatacctcct ttaagagaca gaagagaaga tataatacct ttgtttaaca attttgtaaa
     3181 tgaagtatta aaggatgatg gtctcaatgg aataaacagt atagatgaaa attttgtttt
     3241 gactaaagat gaaatggata agctatataa ttatagctgg cctggaaatg taagagagtt
     3301 aaagacaata gctcaaaaat atgttgtgac aggtaaaatt aaattgagac aagatagaga
     3361 ttttaaaact aaaaaattac ttcctaactc tgaagtagac aaatttaatt ctgaaacgac
     3421 agcaagtgta gaagtccaag atgaatctat aaatataagt aagataaatg atggtaagat
     3481 aagtatagat ataaaagaag taaataagta tgttgaagaa aaaataataa gtatgctttt
     3541 tgctcaagga ctttctaaaa atgaagttgc acaagttctt ggaataagca ggacatcttt
     3601 atggaagaaa tacaataaaa atatttaaat ataattacat ataaattatt ttgaagtaat
     3661 gttaattttt taaaacaagt gttaagaaaa attaacatta cttttttgca aatttttatt
     3721 tttttagaca ggcatatata tttataagaa aaatagttaa aacacttaat ttaataatga
     3781 aaaaaataat aattctaaac aaaatcaatt ttacataaag tgggatttat tggcatagta
     3841 attgcttaat atataatgta agagtaaata caattttagg ggtgatggta tgagtcaaag
     3901 tatggttggt aagcatgcaa tgtggccaaa agaaaatgat gttatattta gcatatctgg
     3961 cagagctcaa gcagcagaga aggcttttgg tatggataat gtaataaatg caacaatagg
     4021 cgctctaatg gatgattcag gaaaattgat aacaatgaaa actgtatatg aagaatataa
     4081 agcattagat aactgtgaga taggtgcata tgcagctctt gaaggtcaac cagattactt
     4141 agaagcagtt aaaaaagtat ttttcagaga ttacttacca gaaggacata taagagtatt
     4201 agcttcacca ggaggaagtg gtgcaataaa attagctgta tggaactata ctaatgaagg
     4261 agatgaggta ttaacatctg attggttctg gagtccatat gtaagtatag ctgaagaggc
     4321 taatagaaaa gtagttaatt accaactttt tgatgaaaat agaaggttta attttgagtc
     4381 gtttaaagaa aaatttgtaa atatagcaga aaaacaaggt agagtcttta caattataaa
     4441 cacaccagcg cataatccaa ctggatatag tgttgcagat gatgagtggg ataaaatatt
     4501 agacttatca aaagaagtcg caaaagataa agacaaaaag ataatatttt tcgtagattc
     4561 agcatatatt gactttgcag gtgatgatga tgtatgtaga aagtttttta agaaattttc
     4621 taatttgcct gaaaacgttc tcgtattggt tggattcagt atgtcaaaag gatttacagc
     4681 ttatggtatg agaatggggg ctataatttg tatatcttca agtgaagatg tagctgaaga
     4741 gttccattac tcatgtgttc attcatgtag agcaaattgg tcaaattgta atagaagtgc
     4801 catggcagta ttatctaaca ttgtaaatga ccctaaaaaa ttcaaagaat atgaggatga
     4861 aaaagaaata tacaaaaaca tgcttactag aagagcagat gtatttgtaa aagaagctga
     4921 aagagtagga ttagaaattc ttccatatat agcaggtttc tttgtaagta taccatgtga
     4981 taatccaaaa gaagtatgtg aagaattgac taaacataat ttatttgcag ttccattaaa
     5041 aatgggttta agatttgcag tttgtgcagt ttctgaagat aaatgtaaga aagcaccaag
     5101 tattataaaa gaagcacttg aaagtttaga agtaaaaata aataattaat ttcattgaac
     5161 aaattgggtg gactatgaat ttaataattg tagatggagg gaattttata tgaaacaatt
     5221 gatgacaggt aatgaagcaa ttgcacgtgg agcctatgag gctggtgtta aatatgcatc
     5281 tgcatatcca gggactccaa gtacagaaat attagaaaat atagcaacat ataaagatgc
     5341 aatagttgca gagtgggctc caaacgaaaa ggtagcactt gaggctgcta tagggggttc
     5401 aattgcagga gcaagaacaa tggcttctat gaaacatgtt ggtttgaatg ttgcagctga
     5461 tccaatattt acttatgcat atacaggggt aaatggtggt atggtactta ttacagcaga
     5521 tgagccggga atgcattcat ctcaaaatga gcaagacaat aggatgtatg caaaatttgc
     5581 aaagatacct ttatttgagc catcaactag tcaagaagct aaagatatga taaaagaagc
     5641 ttttgaagtt agtgaaaaat acgatacacc agttttatat agagttacaa caagactttg
     5701 tcattcaaaa ggattagtgg agtgctatga tagagaagaa gttgaaatta aagagtatgt
     5761 taaaaatgct aagaaaatgg taactgttcc agcaaatgct caaataagaa ggggcgttgt
     5821 tgaagaaaga atggaaattc ttaaaaaatt ctcaaatgaa actgatttaa actactatga
     5881 aataaatgat acaaaaatag gtgttatagc ctctggtatg tgctgtaatt ttgccaaaga
     5941 agtttttgga aaaaatgcat catatatgaa actaggattt acaaatccat taccttatga
     6001 aaaaataaaa gaatttgcag aaaaagttga taaaatatat gttatagaag aaaatgaccc
     6061 atttatagaa gaacaaataa aagcatatgg aatagattgt attggaaaag atgtaatacc
     6121 accatatgga gaaatgacac cagatgtttt aagaaaagct atatttggaa aaacaaatga
     6181 tactatagaa tacaaatctg aattagtaac accaagacca ccaagtttct gtgcaggatg
     6241 tccacataga ggattcttct atgaacttgg aaagagaaaa aatttaatag ttggtggaga
     6301 tataggttgt tatactcttg gatttgctcc tccatataat ggaatagatt atgttgtttg
     6361 tatgggttct gcttttggaa ctgcacatgg agctcaaaaa gttcttaata tgaaggatga
     6421 taatgaaaaa agattggtag gtgtacttgg agactcaaca ttcttccata caggaataaa
     6481 tggactttta gatgttgttt acaatagagg taattctatt tcggttatat tagataatag
     6541 aataactgga atgacaggtc accaagaaaa cccaggttca ggatatactt tacaaggtgc
     6601 taaaactaaa gaagttgata tagaaggatt agttaaagct tgtggaatag aacatgtaag
     6661 agttataaac cctaataatt taaaagaagt aaatgaagca ctagattggg ctttagctat
     6721 agaagatgaa ccatcagtaa taataacaag atggccatgt gtacttaaaa aattctctaa
     6781 agaagatata gaagaattta ataatccatt taagactaag tgtaaagttg accatgataa
     6841 atgtatagga tgtaaattat gtttgaaaac tggatgtcca gctctatcat ttgataaaga
     6901 gaataagtta tcaaatatag atagaaatca gtgtgtagga tgtggagtat gtgcacaagt
     6961 ttgtccaaaa caagcaatag ttaaggagga aaaataatat gactaagagt atacttttgg
     7021 taggtgtagg aggtcaagga actatacttg ctagtaaatt attaactatg ggattgatgg
     7081 aagctggata tgatgtaaag atgagtgaaa tacatggaat gagtcaaaga ggaggttcag
     7141 tttcctcaca agttagatat ggagattgtg ttcattctcc agttatagaa attggtggag
     7201 cagatatatt agtatctttt gaaaaaatgg aagctttaag atggttcaat tatttaaaac
     7261 cagaaggaaa agctttagta aataatcata ggatagattc tatgactgtt ttaatcggag
     7321 gagctgaata tcaagaaagt gatatagatg cagagttaag tagattaaat gcaaaagtta
     7381 taaatgcagc tgataaagct gaagaactag gaaattcaaa aataatgaat gttattttat
     7441 taggatgtct agttaaatct atgcaattag agtctattga ttgggaaaaa attataagtg
     7501 aaaatgttaa accaaaattt gttgaattaa acataaaagc tttccatgaa ggtatggaaa
     7561 tggttagcaa atagtttata atagatataa atagactata gaaattaagg tgaaaggaag
     7621 aaaattatga cttacagaat attagccata aatccaggtt ctacttctac aaaaatagca
     7681 gtatatgatg gagaagaaca aattcttgtg aagacgatag accatccagc tgaagagatt
     7741 gcaaaatata atactataca agaccagttt gaaatgcgta aggaagcagt tttgaatatt
     7801 cttaaagaaa atagtataga cttaaaatct cttagtgcaa tagtaggaag aggtggagtt
     7861 ttaccaccag taaaatcagg agcatattta gtaaatgaag aaatgattga tgtactaaga
     7921 catagaccag tacttgaaca cgcttccaat ttaggtgctg ttgtggcaca tgcaatatca
     7981 gaacctcttg gaatcaactc atatatttat gattctgttg cagtagatga gcttatagat
     8041 gtagcgagaa tatctggact ttgtggaatg gatagatcaa gtgcagggca tgcattaaat
     8101 actagagcaa tggctttaaa atatgctaag gataaaggaa aagattataa gagcttaaac
     8161 ttaatagtag ctcacattgg tggaggagta agtatttatc ttcatgaaaa aggaagaatg
     8221 gttgatatgc tatctgatga tgaaggacca ttttctccag aaaggtcagg aagagtacct
     8281 gctacaaaat tagtggctgc ctgttattca ggtcaatatt cagaaagaga aatgactaaa
     8341 aagataagag gtaaaggtgg tatagtttca tacctaaata ctgtagatgc tagagaagtt
     8401 gaaaaaatga tagcagaagg aaatgaagaa gcaaaaatta tttatgaagc aatggcttat
     8461 cagttagcaa aaggtattgg agagttagca actgtagtag atggaaaggt agatgctata
     8521 attataacag gtggaattgc atattctgaa atgtttactt caatggttaa aaagaaagtt
     8581 gagtttatag caccagtaga aattatggca ggagaaaatg agttggaatc acttgctttt
     8641 ggaactttaa gagtactaaa tggagaagaa gaagctagaa tttatagtga aaattaataa
     8701 gaaaaactaa aaatgtttat atactaaaaa agtggtatat ccgtttttta tacacgaaag
     8761 cttagagtat aggtgaaaat gtataaaatt tggattgcca ctttttataa ttaaaatttt
     8821 atcttaacct aataaataat tctgtaaaat ttcgtattta tatatatatt ttattggtat
     8881 ttattgttat tattattatg aggagtgatt tttgatggga aaaataagtt taaaaagtat
     8941 gataagatta ttttcaggtt tttttatatt tgcaatttct tctgtgctta tgattaatgc
     9001 acatgtaggt cttatgcctt gggatgtact tcaccaaggt ttatctataa agctaggcat
     9061 aactataggt caggcttcta taatggtagg agttgtaatt gttatattgg atgcagtttt
     9121 tggtgaaaat ataggatggg gtactttact caacatgaca tttataggaa tttttattga
     9181 tttagtaata ttttctggag tgatacctca tgcaagcaac acttatatag gtgtgtttat
     9241 ggttgttata ggaattattt tggcagctat agcaagtttt ctatacttag gtgtttgttt
     9301 aggaagtgga ccgagagatg ggcttatgat tgctcttcag aaaaaaacta ataaatctgt
     9361 acgtcttgtt agaacaattc ttgaaatact agcattagtt gttggatggt tattaggagg
     9421 ttctgtaggt attggtacgc ttgtaagtgc tttaggttta ggatatgtat tacaaatagt
     9481 gtttagaata tttaaatttg acacaaaatt gctgaaacat agatttatta tagatgatat
     9541 aagagaatgg aaggaaaaga aaagcaatga acataaatgt aaatcaagta ttgtaataaa
     9601 aaatgagcag aattaattat gctaaaatat atttgtagtt tatctaattt atagtaaagt
     9661 caaggagatt ttgaaatgga attatgggat ttatataatg ctgatggaat taaaacagga
     9721 aatgttataa aaagaggtaa ttctattgaa gaaggttatt accatttggc agttgaagtg
     9781 tggattttaa atagtaactc tcaaatttta attcagaaaa ggtctaaaag taaaaaaaca
     9841 ttgccaaata tgtggggaat gacaactgga tgtattgttt ctggggaaga cagtttagaa
     9901 ggagcaattc gcgaagcaaa ggaagaaata gggatagata taactaaaga tgagatgaaa
     9961 gtttttagaa gtatgattca tgaagatact ctttgggatg tatacttagt taaaaaagaa
    10021 tatgatatat ctaaagctat tttacaggag gaagaagtaa gtgatataaa gtgggtaagc
    10081 acagatgaaa taagacaatt actaaaagag ggtttgtttt ttgaatatcc agagatatac
    10141 gaattgctat atgagataga taataataaa ttaaatatat gatgtagagc agatttcagt
    10201 ataagtaaga ttatttaaaa tgtatcttct ctaaatttta atattgtttt atgaaaatta
    10261 ataagttatt tttagtattt ttctacttgt tttttgagat taaaataaaa agggcagtca
    10321 ttataaagtc ataaaaattt ggggaggatt taaactatgg aagataacaa aggattggca
    10381 cgtgacagtt caaaatataa aattgtttct atatctgtcg tagtaattat tctaattaca
    10441 ttttggtata tgttaaatat ggtgctttta acatttatta tgacttttat tttctataac
    10501 ttgcttgtag ccacaagaaa acgaattaag aagttttctt ctttaaatat tccagattca
    10561 ttgataatta tagtgttata tgcactattt gctatattgt tagtattgat tagctatgca
    10621 gttgtaccaa taattatagt tcaacttaca gagttgagta gggtttttag tgattttgat
    10681 gtaaatcaat ttgctcaatc tttaggaccg aaattgtatc ctattgtctc aaagctggat
    10741 tttaataaat atatttcaca agcagggcta cttatagcat caacagcaac aaaagttgga
    10801 agttttggag taaatatatt attggcattt ttactgagtt tactcctttt acttgaaaaa
    10861 aatgaaatta aaaattttgg agataaactt tctgatagta agatttcttt tatttataat
    10921 tcgcttgtat tttttggaaa gagctttgtt aaaaattttg gtgaagtaat gaaagtacaa
    10981 gttatgattg cctttataaa ttctgttgtt tctatgattt tcttaggttt catgggattc
    11041 cctcaaatat gggctttagg atttatgatt tttgtgttgg gtcttattcc agtagcagga
    11101 gttatagtgt ctttgattcc attaactgta atagcattta atacaggagg aataacaaag
    11161 gtttttggag ttttacttat gatttgtata gtgcatgcag tagaaacata catattaaac
    11221 cctaagttga tgtcgaatag aactaaactt ccagtttgtt ttgtttttat tattttactt
    11281 gtaggagagc attatttagg tgtatgggga ttactaattg gagttccaat atttatgttc
    11341 cttatggata ttctgggtgt taaatttact tctaggtaat atattaaaat aataatttat
    11401 ttttatatat aaattatgaa ttgttttaaa aaagaaccta taaatagaca tcattaataa
    11461 agacatctat ttgataggtt caattttgct ttgtataaat actataaaac taaataaaaa
    11521 gaaatttatt tcatttcaaa agtttcacaa cttgcatttc tttcatttat atgaactttt
    11581 tcagctttgc aaagttcatt tttattgtat ttacatttta cagcttcaca atgaatgtta
    11641 tctgtatcaa cttggttagt ttcattagaa cgactagtta taccagatgt atatttgtct
    11701 tcaaaagaag cacaataagt attttctgta gtagttgctt gcattccatc tacttttata
    11761 ctaccagcat aacaatatcc actagtatta taagcacaat tagtagcagc acaatttaaa
    11821 ttattatttt tcataaataa cctcctaagt tttatttaaa cttattatgt gaagttatct
    11881 aaattttata cacttattta caattacatt tatcacattt aacaactaca tctttggaag
    11941 tttcccttcc taaattttta ttaacatgat acacatcaac attttcagtt gatccacata
    12001 tagaacattt aaaattgttt tctagtaggg ttctttcttt aaataacttc caatacatag
    12061 aattgatgta atcattataa tttaccttga ggcatgtctc aagaaagttt atgtatagat
    12121 tgtctaaatc tcctgtattt aattctgtat attctggttc aaaatattca caacatcctc
    12181 taaaatcggg ctttgtatct gaaataacac atctaatatc atatctatag tctaggctag
    12241 gccccttaaa tgaaagatgt gtgcaaaaag aacaagatat ttctggtaga tttttttcaa
    12301 gttcatgtaa tttattattc ataagtattc ctccaaaaaa tttattttaa gtatataaat
    12361 gaatagatta ttttaaaact tttatttatt tatattagag atttaggata aatattccaa
    12421 taaggagtaa atacttaagt atttattact gtattaaata aaaaagaggc aaatctaact
    12481 tgagattgcc tactttttta tcatttttta ataaaattta ttctaagtat tattttattt
    12541 agatttagtc agccaactta gtatctgctt tgctttttaa ctttctacca gagcgtacag
    12601 ttaaaatagc atataataca gtaaatatgg cagctaaaac atatgatata tttatgttta
    12661 agttaaatcc aatttgagca ttaaatatat aactgaatat aacaaaggaa taaaacatac
    12721 caggaattaa gcttataata taattctttt cttttattat aaggtaaact gtaatcattg
    12781 caaatgcaaa tatggcaata gtttgattac tccaagagaa gtatctccac aatatattaa
    12841 atccagaagc actaagcttt gcaaatataa ggatggctat gacaggaata aatatacaga
    12901 ttgacaatat aacacgatgt ttcttttcct tttggtcata atgaaagtaa tctgcaagca
    12961 ttaatcttaa agatcttaaa gctgtatctc cagaagttat tggtaaaaca attacaccta
    13021 ttatagctat gataccacca atagaaccaa gtaaatctct tgcaaccaaa cctattacat
    13081 caggagaacc tactaattct ttaggtattc ctttattgta aatacccata gcagctgcag
    13141 cccaaatcat tgcaattaaa ccttctaaaa tcatcatatt ataaaaagta gtttttcctt
    13201 ctttttcatt tgaaactgat cttgctataa gagtagcttg agttgagtgg aatccagaaa
    13261 caataccaca agcaactgta acaaagaatg taggaataag aggaatacca tcaggatgaa
    13321 tacctttcca atttgcaaga cttaaattag ctaaatcata accttgtgta aagattccaa
    13381 ttccaacacc agcagcagat aaaagtagaa tagctccaaa tattggatat acctttccta
    13441 tgattttatc aattggaaat agtgttgcac acaagtaata tagaaagata agtccataaa
    13501 ctatccagac aactggatta tttatagtcg atttcatatt taaaatttga gtaacaacta
    13561 aatccccagg tgtataaata aaaactgcac caactaaaag cattaaaaga caaaggaata
    13621 tattatagac ttgaaatact ttattaccta aaaatctact gataagagaa ggcatttgtg
    13681 ctcctttttc tcttatacta atcattccac tcatatagtc atgcaaagct cctccaaata
    13741 cacagccgat aggtattagt atgaatgcta ttggaccaaa caatatacct tggataggtc
    13801 ctagaattgg tcctgtacca gctatattaa gcaactcaat tagactattt ttccattttt
    13861 tcattgggac atagtctact ccatcacttt gagcaagtgc aggtgttttt ctgtcatctg
    13921 ggccaaatac tttttcacaa taagcaccat ataaagcacc tcctattagt aatatagcca
    13981 agccgattaa gaatgttgtc ataatatcac cccatttata aaattttttg gtctttgtat
    14041 acatattatc taaatgtgta gatttatatt gaatttaatt ctggacaacc tacaaattct
    14101 ataaagtatt acaactaata taatttcaga aataaataca tatacataac catgtactta
    14161 gtatacaggt atttggtaat attttcaatg ttatagcaat aaagaatata aacaaaattc
    14221 tgataatatt ttacaaaaaa attaaaaaat ataaaaatta gtttaaatag atggagaaaa
    14281 aaggaaaatc aattgagaat ataaatgtct atatcttaac aatattaaga ggtttaaaat
    14341 tcttgaagaa agaatagtca agtgatataa tgggtttaca ggtgtatata cactagtaca
    14401 tatagaaagc ggtgcaatta tggataaaga tttaacatat caaatcaaag agctaaagaa
    14461 agaaaaaaat gcaataatac ttgcccattt ttatcaacca ccagaaatac aagaattagc
    14521 agatgcagtt ggtgactcat attatttaag tgagattgct agagattgta aagaagaagt
    14581 ggttgtattt tgtggagtaa ggtttatggg agaaagtgct aagatattat cacctgaaaa
    14641 aactgtattg atgccagtaa gtaacgctgg gtgtgctatg gcagatatgg tagatgaaga
    14701 aggcgtgata aaattaaagc aacagtatcc aaatgctttg gttgtatgtt atataaactc
    14761 tacagctaaa gttaaggcac attgtgatgt ttctgttaca tcttctagtg caattaaaat
    14821 actagaaaac atagataata aagaaattat attccttcca gataaaaatt taggaggata
    14881 tattgcagaa caatttccag ataaaaactt tatattttgg gacggatatt gtaaatacca
    14941 taacaatata agagctgaag aaataattga gttaaaagat aagtataaaa atgcagaagt
    15001 attagtacat ccagaatgta aaaaagaaat aagagattta ggagattatg taggtagtac
    15061 atcaggaata ataaaatatg ctactaatag taaaaacaaa gactttataa tagcaactga
    15121 agaaggtata ttacatgaat taaagaaaaa taatcctaat aaaaactttt atattcctgg
    15181 tggaaaaata ctatgtacag atatgaaaaa gacaacatta gaaaatttat atagtacact
    15241 taaaaatatg gaaaatgaag ttattgtaga agatgaaatc atggaaaagg ctttaaattc
    15301 actgcttaac atgcacaaat tagcagaagg atagagggat agacttatga atttagaaca
    15361 agatgtttta atagttggaa gtggagtttc aggattatac tgtgcattaa atttagataa
    15421 aagtttaaat gtgctagtag tatcgaaatc aacaattgaa aacaacaata catatcttgc
    15481 acaaggtgga atttcaactg ctagaaatat tgatgatata gaatcctttg tagaagatac
    15541 aatgaaggct gggcagtata aaaatagagt tgaagcagtt caagtacttg cagatgaatc
    15601 tatagaaaat gtaggtcaga tagtagaata tggtatgcct ttagacaaag aaaatggaga
    15661 gatagattac acaagagaag gagcacatag tgtaaatcga atagttcata gtaaggataa
    15721 tactggagaa gttgttttta aaactttatt aaaagaagct aaaactagag aaaatataac
    15781 tcttatagaa gatgcatatc ttttagatat attaaaagat ggcaataaat gtataggagc
    15841 tagaattttt aaatctaaaa aagagattca tgttttttca aaaatagtag ttttagctac
    15901 aggtggaatt ggtgggcttt ttaaaaattc tactaatcaa agacatctta caggtgatgg
    15961 aattgcaata gctttaagaa ataatataaa aatagaaaat ttagaatata ttcaaataca
    16021 tcctacagcc ttttatgaag aaaataatga aggtaggaga atgcttatat ctgaatcatt
    16081 aagaggagag ggagctaaac ttttaaataa aaataaagaa agatttgtgg atgaacttct
    16141 tcctagagat gtagtttcaa aagctatttt tgagcaaatg gaaaaagata aattacctta
    16201 tgtgtattta gatgcaacac atttagatag tgaatattta attaatagat tttcttttat
    16261 ttataatgaa tgtttagcta gaggaacaga cataacgaaa gaatgtataa aggtatctcc
    16321 tgcacaacat tattttatgg gcgggataca tgtagatttg gattcaaaaa catctatgga
    16381 aaatttatat gcagttggtg aaattagttg tacaggtgtt catggagcca atagattggc
    16441 aagtaattca ttacttgaag ggcttgtatt ttcaaaaaga gcagctaaaa atataaactc
    16501 agttatagat aatgtaaaag ttaagtttat agatgtacca gatatggata tagatataga
    16561 acaggtaaaa aaagaaaata aaatattagt cataaaagaa attgaaagaa caagtgagga
    16621 ttttggcgat gaattatttg attattgata gaatgataca ggatgctttg atagaagatg
    16681 ttccaagtga agatataaca actaattcta ttgtggatga aaattctaaa tctactgtag
    16741 atttaatttg caaacaagat ggtataatag ctggcttagg tgtatttaag agagtttttg
    16801 agatacttgg tgatgtagat gtaaaattat ataaaaatga tggtgataga gtaaagaatc
    16861 gtgaaaagat agctgtatta acaggtagta ctagaaactt acttgtagga gagcgtgtag
    16921 cattgaatta tttacagaga atgagtggta tagctactat tacaagtagg tatgttgaaa
    16981 agcttgaagg tacaaataca aaattattag atagtagaaa aacgatacct aatcttagaa
    17041 tattagataa gtattctgtc aaagtaggtg gaggatgcaa tcatagattt aatttatctg
    17101 atggaatatt gcttaaagac aaccatattg gggctgctgg tagtgttaag aaggcagttg
    17161 aattagctag aaaaaatact tcttttgtta gaaagataga agtggaagtg gaaactttag
    17221 acatggtaaa agaagcaata gaagccaatg cagatataat aatgttggat aatatgagtt
    17281 tggaaatggc aaaacaagca gtagatatta taaatggaag agccattgta gaattttccg
    17341 gaaatgtaaa tttagatact atagaagata taggaaaaat tggtgtggat gttgtttctg
    17401 taggagcgct tacacattct gttaaagctc tcgatataag tatgaagaat ttgagaaata
    17461 tataaatttt atattgaaat aaacttaatt aaaatagact ccttaaattt gttttataaa
    17521 tttaaggagt ctatttttta ttcattaaaa ttaataaaaa tagaaaaaaa tcaatcaata
    17581 atttaataaa aatagataaa tactatatac acttttaata atatagttaa tatctatttt
    17641 acagataaat aagaataaac ttataatata attgtatctg taaaattttg taaaatataa
    17701 aaagtatagg gggaataaaa atgaaagtag cttatatttt tagtagtact aatacacata
    17761 aaattctaga caaaatgata ataccacaac ttgaacaagg aactcatgga gtagacgttc
    17821 tagggatgtt tttctttatg gataatacct tatttttatc taaaggtaat cctgtaggcg
    17881 agagactaag taaattacat gaaaaaactg atatgataat aatggcttgt gaccaatgtg
    17941 ctatagaaag aggtatagag aataatttgg ttgatggagc tacaattgga tgtttcccaa
    18001 acctatatgc ttgtttaggc agtgcaggtg tggaccaagt tataacgtta taaattagta
    18061 taggatacaa tccatagaaa aatttatttt ctgtggatta ttttaagtaa aagataaatt
    18121 gtttaaagta ggggatgaac aaatgtctaa aattttagtt gaatttataa acacttgacc
    18181 atcttgtgat gaacatggag tgtttataaa aaaaatgtca gaaaagtatg ctgataaatt
    18241 ggaaataaaa ttatatcaag cagggaaaga tttttcgtat ataaaaaaat atgggattat
    18301 aacaaaagga actttaataa taaatcagaa aaagaaatat gatagattaa ataaagatac
    18361 aattgaaagg gcaatagtag aagctataaa caataattaa aagtttaaaa attaggagta
    18421 tcaaaaatga atatattaga aattgtttta aatggagtta aagatactat agtagcttct
    18481 atagttacac tgaatggagc atcaggatgg cttatgataa gttttatctt ggcaggtgta
    18541 cttcacaatg ttttaactcc aagaaggttt caaaaacaac ttggaaataa gaaattttct
    18601 tctttaatta aaagtactat ctcaggaatg tttttaccaa tatgtagttg tggagtaata
    18661 ccacttggaa taagtatgta ttattcagga gcatatttag gaccagtact tgcttttatg
    18721 acatcaactc caataataaa tccaatagct gtagttcttt gtctaggtct tttaggtcct
    18781 aaagttacaa tcatttatct aatagctggt tttttagtac catttttagt aggattttta
    18841 ggaaattgtt ttggaaaaga agaattatca cttcataatg attcagagga agaagtaata
    18901 gaattagaag aagaaaaaag aagttttatg gaaaatatga ttgatggtct taaatggtct
    18961 tttggtgaat tagcccttac tattagtaaa tatgtagtaa tgggtatggt ttttgcagga
    19021 tttataacaa ctatttttcc aaatagtata attcaaaaat atttaggaaa tccaggtttg
    19081 ctatctcttg gaagtatagc aatacttgca tgtgttatgt atgtatgtgc tgtaggacat
    19141 ataccgttta tagcagccct tgttgcaagt ggagcatctc ctggtatagc gataacattt
    19201 ctaatagctg gagcagctac aaatctacca gaacttataa gtatgtttaa acttattgga
    19261 aaaagaactg ttattatata ttctgtaact ttgacactgt cttcaataat aattggatat
    19321 ataacaaatt tacttttagt gaataataac tcagtaaatt tagatgcaac aaattcttca
    19381 atacagttgg caaataaact aatgttaaat atacctgata gttttgagta tgtatgtact
    19441 attttaatta ttttatttgc atttaaatca ataataccaa agatgaaaga ggtcatagga
    19501 aatcatgctt aaaaagatag ttataatatc ctgcatagta gttgtgttaa tcattttatc
    19561 aaaaatagtt gatgataaca tcaaagaaga tgcttctatt ccaaatgtga ataaagaaac
    19621 attagaatat tttagaaaaa attataaaga agacataata acttgtgctg aagaagactt
    19681 aaataatgat gggaaaaaag atttagtagt tatatataaa aaaagcaata attcaaatga
    19741 aatggtagtc gtagtttctg ataaaaatag ccactatata acaaagccaa taccagcacc
    19801 tatagagaat caaactataa cctttaaaaa tattgatgat aaagcaccaa tagaagtaat
    19861 tgtatcaggg tctaaaaatg gtaatgtagg atatgctatt tacagagtag agggtaaaaa
    19921 atttgttgat ttatttggcg aagatatgga caaatgttgc taaaaataaa aataatacat
    19981 aaaggtggga aatttatatg aaattatcta agaagattca agcattaatc ttatttggtg
    20041 taatgggtac atctatatta acaggatgta gtagtaaacc aaaagaaaaa gaagaagcaa
    20101 aaactggaaa agatgattat acaataacag taggttatta taattgtgac catatgactg
    20161 cgggaccagt agcagaatcg gcaggaatat ataaagattt aggtcttaat gtaaaaactg
    20221 ttggaaatgg taaagttcct gaagctatgg cagcaggaaa aatggatgca ggttacatag
    20281 gaactaaggg gttagttgga gcaataccta agggttcacc aataacaata gcagctaaca
    20341 accatactgg tggttctgaa tatttaatag tttcaaaaga tataaaagaa cctaaagatt
    20401 taataggtaa aaaaattgca acagatatga gtgatttctt atggacaagt gattatggtc
    20461 cagaaacagg tctaccaact gacccatcaa aatatgaagt tgtaaatatg gattcagaca
    20521 aagataaata tttagctctt aaaactggga aaattcaagc ttttacatct tgtgaccctt
    20581 ggggttctgt agctgaaaat gacggtgcag gaaaaataat agcatctact caatataaag
    20641 aaaaagctaa tggcaaagaa tataactgtt gttcattctc attaaacaaa aactttataa
    20701 aagaacatcc agatttagca aaaaaattgg ttctagcaca tacaaaagca atagaatata
    20761 tatatacaaa tccagctgaa gcagctaaaa tatttgcaaa atattataat gtagaagaag
    20821 aagttgcact tagaactatc tataagaaga ctgttggaga aggtagaact cttacttgga
    20881 aagttacagg tgaagaatat aaaaataatt tacaaatgta taaagattta aaggctttag
    20941 atgatatacc taaatatgaa gatacgattg atacaagctt attggactct tgtggagctg
    21001 atgattttga caaatttata aaagaaaaag ttaacccaga gtttcctgaa ggtatgagtt
    21061 atgaagactg gaaagcaaag gtattataaa taaatggaga atatgaaaaa tataataata
    21121 ctttttatca ttattttggg aagtatattt ataatatttt ttaattttga agataaagaa
    21181 gaaataaaag gaaaattaag aataggggta tctgatgata cctctggttt tgtaataaat
    21241 tatatggtaa atagagacta ctttgaaaat ataaaagtaa gtgatataat ggatattttt
    21301 acaattaatg attgctgagc aagtacaatg cagtgggctc tgagttcaga ggaaatagat
    21361 atagcaatca tatgtaaaga tgctgcaaaa caatatgtaa atgtaaatag tggatttgaa
    21421 attgttggta ctgtagttca aaattctgat atatttctat taagtgataa taatcctgaa
    21481 aagataggag tcattcaaaa tagagattac cagtcagaat tggttaaaaa atactacaag
    21541 aatgtggaag tagctccctt attagggact gcactagcat atggattaga aagtaattta
    21601 gtagatggtg ttgtaataga ttgcataaag tcaattgggt tagagggcaa aagaaaatct
    21661 acaactaaat taggagatta tgatacctat gtattagttg taagtaaaga gtttaaaaaa
    21721 agtaaagcat atagtgattt tataacactt tacaataaaa gtgttgatgc tttaaagaat
    21781 aaagctacat ttaagaaagc attaaaagag tacaggaata taagaaatat agatatggag
    21841 gaaataagca attggaaatt aaaatttcta aagataaaag cgatagatta actaagaaaa
    21901 aaactgatgg tagtatggat attttatata aaataatact attagttatt atatttttag
    21961 tctggcattt tgcagcaaaa gatataggga gttctttgtt acttccaatg ccagtagatg
    22021 taataaaagg tttctttttc tgtgtgacag atgcagagac agtcactaat ctttttataa
    22081 cattgcagag agtacttaaa ggttttatgt atgcattatt gtttgggctt ccaataggat
    22141 ttattatggg attttctaaa acttttgaaa gggttttatc tccagtagta gattctgtaa
    22201 ggcaagttcc aataatggca tgggttcctc ttactatagt atggtttggt ataggagatg
    22261 gtccaacaat atttttaata gctttttcag gggttttccc tataatttta aatactattc
    22321 aaggagtaag agcaatatca aaggattatt ataatgcagc tagaagtatg ggagcatcgc
    22381 caattgtgat atttacaaat gtaattgttc ccgcatctct tccagatata ctaactggtt
    22441 caaggattgc tataagtaca ggatggatgt ctgttatctg agccgagttt atagctacga
    22501 gtgccggtct cggttactca atggtacaag ctcaaacatt aatgcataca gatgtattaa
    22561 ttgggcttat gatatttgca gctttaatag gatttataat agatagggta ttaaagttta
    22621 taaataaaat cctttgtaga tggaggtttg cagattaatg aagttaagtg taagagatat
    22681 aaataagaca tttgtaaata atagagtaca tacaaaggtt ttagaagata taagtatgga
    22741 tatagatgat ggacaatttg tctgtctttt aggaccatca ggttgtggaa aaacaacttt
    22801 acttactata ataggtgggt ttcaaaaatc agaacgtgga gatgttttta taaatgataa
    22861 aagagttaaa aaaccgggca tagatagagc ttttatattt caaaattatg ctttatttcc
    22921 ttggaaaact ataagaggta atgttctatt tcctatgaaa cagcagaaaa taccaaaaga
    22981 aaaaagagaa gaaatgctag aagaactttt ggttatgtca gacttgaaag gaaaagaaaa
    23041 actgtttccg catcaattat ctggaggaat gaaacaaaga gtggccatga taagagcttt
    23101 agcatgtaat ccagaggtat tactaatgga tgaaccatta ggagctgtag attttcaaat
    23161 gagacaaaat ttacaggaag agctagaacg aatatggata aagaagaaaa taactgcatt
    23221 aatggtaact catgatgttg atgaagctgt atatatgagt gatagagtta tagtaatgtc
    23281 gagagataaa ggaagaatta ttgatgatat aaatatagat attccaagac ctagaattag
    23341 aggaagccaa aaatatgaag agtacaaaaa caaattaact gatactttat caaagtgtta
    23401 tgaagtttaa agaggagtag acatgagtca aatagaaaaa tacaatagtt tggataatac
    23461 acaacagaaa ataagaatct ctattatgga tatgataata gataaaggtt ctagtgttac
    23521 acttcaagaa gtgactgaat atataagtaa aaagttgaat atagaaaaag aatatataga
    23581 aaggacacta caatatttta tttataaaaa tataatggtt gttgatggga atagtataaa
    23641 ttttatatat cctgtatcag cattgccaac aaatcataaa gtaactttga gagataatag
    23701 aagtttcagt gcaatgtgtg ctatagatgc tataggaacc tcttgcacat tcaaccaaga
    23761 tataaaaata aactctattt gtagtgctac aggtaaggaa atagaagtaa ttataaaaaa
    23821 tgaaaagatt gagtatgtga ataatccaaa cttaagagtg cttcatataa atcttgataa
    23881 gcatctaaat tgggctgcta gttgctgaaa tataatgaat ttcttctgga cgaagagtga
    23941 ttttgatgct tggacaaacg aagcgggatt atctaatgat gaagatatat attgtttaga
    24001 tattaatgag gcaatagtag aatcatataa aatatttaaa ctcaaacaaa aggtactatc
    24061 atagatatac atatatgaaa aactaaaaat gacctttaga taaaaatgat aggtaatatc
    24121 catactatat aaattagtat agagtaggga tgtgaaaagt atttaaatct aaaggtatat
    24181 ttttagtttt ttttagatga ttagatagcc ttattaagta tatatttatt tataaccttt
    24241 gcaactccat tttcattatt agtatcagta acataatctg caatttcctt tatactatta
    24301 cgtgcattcc ccatagccac accaagacct gcatacttta tcatatgttg gtcattttct
    24361 tcatcgccaa cagcaatagc attttctata ggtatattta gattcgtaca taatgtttta
    24421 agagcagttc ctttattagt agttttacct aaaaattcta gataaaaagg agcagacctt
    24481 actatagtat atttattgaa taaattttta ggtagttgct gtatgatttc ttccaatctt
    24541 tctggttcat caactatcat aattttacag attttaatag attcatcaat tttatctttt
    24601 tgtatatatt tgacttctat attatttaat ttcgcttcat gaagtgtata tttgccaggc
    24661 gtttcatttg gtgtaattaa atttgtcatt gtatttatgt gtattttagt cttatatttt
    24721 ttacaaacgt tattatatat aaaatcaaaa tcatctaaac tcatttctac atcatgtatg
    24781 attttctcac ttttaacttc ttgaataatt gctccattaa agcatataac ataatcacct
    24841 tcatctgtta aatttagttg atttagaagt tcttttacac caggaagagg tctgcctgtt
    24901 gttataacta cttttgcccc agcccttttt gcctcctgaa tggactcaaa gacttcagga
    24961 gtaatccttt tttgtgtatt taatattgtt ccatcaatgt ctagtgcgat taatttgtac
    25021 atatcaacct ccaataaatt atatactcaa atttcctgtg aaaacgttga cacagctagt
    25081 gttgaacaaa gtttcagtgg gaaatatggt ttgttttgta tactattata tcaagagata
    25141 agtaatttag aaagtttaat aatattaatt ttttgataaa aatattactt atgtgagatg
    25201 agaatgtaaa aactttgtaa tcaataattc caaaattctt aattacaaat aatggtatcg
    25261 tttgcattgt taatataaat aaatgtatat tatatagtta gaagtttgaa taaatagact
    25321 gatggtaatt tgttatatta gttagttttg tgttataaaa tattgtaatt ccattaatca
    25381 tatgttatta ttcaacatga ttataatata aagaatattt gatatatata ataatttata
    25441 aaagagtatt acatagtaca tgtaaatcta tatttataaa tacaataaag taaagttgta
    25501 aaggagtgct ttaaatgaag ttttcagagt ttaagtatga aagacccaat tataatagta
    25561 tgaaaaaaga gtttttgagt tgtgtagaag atataaataa ttctcgtaat tataaagagc
    25621 aacaaaaaaa tatacataag attaatttat taagaaataa aatagaaacg ttgtcaaata
    25681 tagcttcgat aagatatagt acagacacat ttaataaatt ctacaaagaa gaaaaaaatt
    25741 attgggatga atatatgcct ttgtatgaag aattaaattc atatttttat aatgccattg
    25801 taaattcaaa atttaaatat gatttgataa aagagtttgg agagcaattt ttcacaatag
    25861 tagagtattc tttaaaaagt ttttccaaag aaataataag tgaattgcag gaagaaaata
    25921 aattgtgttc agagtatact agacttttag cttcagctga gataatgttt gatgggaaaa
    25981 taagaaattt atctggtatg gggaaattca tgtattctaa gaatagaaaa acaagagaat
    26041 tagcaaacaa agcatattat aatttctttg aagaaaatga aactaaattt gatgacatat
    26101 ttgataaatt ggttaaactt agagataaga tgtctaaaaa attaggtttt gaagattttg
    26161 tagagcttgg gtatgttaga atgatgagaa gtgactacag agaatatatg ataaaaaatg
    26221 ttagaaaaca agtactaaaa tatgttgttc caatggcaaa tgagctttat gaaaaacaag
    26281 ctaaaagaat tggtctagaa tatttaagtt acatagatga aggcgtggaa tttttaacag
    26341 gaaatgcaag tttaaaggga gattcaagat acataattaa aaatggtaaa aggatgtatt
    26401 ctgaactgtc aaaagaaaca aatgaatttt ttgattttat gttagaaaat gaacttatgg
    26461 atttagaaac gaagaaagga aaaggagctg gagggtattg tacttatata ccagattata
    26521 agtcaccatt cattttttct aattttaatc aaactgctga tgatatagat gtattaacac
    26581 atgaggcagg acatgcattt cagttgtata tgtctagatg gattgatatg ccagaaatta
    26641 attttccaac gcttgatagt tgtgaaatcc attcaatgag tatggaattt ataacatggc
    26701 cgtggatgga tttatttttt aaagaagata cagataagta caaattcact cacttatcat
    26761 cttcaattaa atttatacct tatggagtaa ttgttgatga atttcaacac tatatttaca
    26821 aaaatcctaa tgtagataag tcaaaacgaa aagaaatctg gagattttta gagaaaaaat
    26881 acttacctca tagaaaatat ggtgataatt cttttttaga gagaggttgt tggtggttta
    26941 aacaaggaca tatatttaaa aatccgtttt attatataga ttatgtatta gctcaaattt
    27001 gtgcgttaca attttggaaa aaaatgattc aagatagaga tgcaggatgg aaagattata
    27061 taaatatctg taaagttgga ggaacaaaat catttttaga tattgtgagt atgggaaatt
    27121 tgtattctcc atttgatgat ggctgtattg agtctattat aggtgatgtt aaatcttggt
    27181 ttgatgaaat aaatgacagc aaattataaa aaattatgag aattttattg tataaaagtg
    27241 aaaaattaaa aaatatataa aaagtgatta tttgttgtga aaatagtctt gtttttaact
    27301 aaattgataa aataaactaa aaaagatttg tacttaaaaa aaaaagaaaa tacaagaa
//
LOCUS       DAJMZY010000048        27356 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.048, whole genome shotgun sequence.
ACCESSION   DAJMZY010000048 DAJMZY010000000
VERSION     DAJMZY010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 27356)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27356)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27356
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.048"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            complement(<1..896)
                     /locus_tag="OE968_002004"
     CDS             complement(<1..896)
                     /locus_tag="OE968_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009243519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HCP7219283.1"
                     /translation="MKLKHIAIIGSLFPILFSIVLFFGVLMSADSDDENSNFSSGITG
                     MNLSAEVLKHQPMVEKYAKEYGISEYVNVLLAIIQVESGGTAKDVMQSSESLGLPPNS
                     LDTESSIKQGCKYFASLLSSCKNQGINDLNVAIQSYNYGGGYVGYVAGKGKKHTFNLA
                     ESFAREKSGGKKVTYTNPIAVAKNGGWRYGYGNMFYVELVNQYLTVPQVSGELAQKVM
                     NEALKYQGWKYVYGGSNPNTSFDCSGLTQWCYGKAGISLPRTAQMQYDATQHIPLSQA
                     KAGELVFFHSTYNAGSYVTHVG"
     gene            complement(893..3085)
                     /locus_tag="OE968_002005"
     CDS             complement(893..3085)
                     /locus_tag="OE968_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HCP7219284.1"
                     /translation="MKERIQSAFTKKKIFHFLKMALFVVALSLILLSLLGTVAHATGL
                     VDDTINAENLYSKYPLSNYQLDFYVDNSWAWLPWNWLDGIGKSVQYGLYCITNFVWTI
                     SLYLSNATGYVVQEAYKLDFINDMADSIGQSIQTLAGVTSSGFSTSGFYVGFLLLIIL
                     VVGLYVAYTGLIKRETSKALHAVINFVVVFILSASFIAYAPDYIKKINEFSSDISTAS
                     LDLGTKIMLPNSDSEGKDSVDLIRDSLFSIQVEQPWLLLQFGNSNAEEIGTDRVEALV
                     SASPENEDGKTREEVVKTEIESNDNNNLTIPQVVNRLGMVFFLLFFNLGITIFVFLLT
                     GMMLFSQILFIIFAMFLPISFLLSMIPSYESMAKQAIVRVFNTIMTRAGITLIVTVAF
                     SISSMFYNISTDYPFFMVAFLQIVCFAGIYMKLGDLMSMFSLNANDSQSMGRRIFRRP
                     YLYMAHRARRMERRLAGAVTAGGVAGAVAGSTVSNARTTRNNSAKDNRGNTSSSMGQR
                     AGSKVGAVLDTKNKVKDKANAMKETVKDIPTQTAYAVHSAKEKAKTSVSDFKRGMVQE
                     QQSRQSGRLEKQEQHKKNIADKRMELQKAQEARQARKTDGSATTGATRPHERPVTASA
                     IPKTNVEKTQEVKRPATTSTSKAGEPVKTNSVKERPLSSGTSDGKIPQSAQTVHSKNV
                     EKVVSHETHQNYKAERTTKAQTVEQAKRTTEHTEKNRNLVTKKGQKKK"
     gene            complement(3085..5535)
                     /locus_tag="OE968_002006"
     CDS             complement(3085..5535)
                     /locus_tag="OE968_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HCP7219285.1"
                     /translation="MFPIKYIDNNLVWNKDNEVFAYYELIPYNYSFLSAEQKFIVHDS
                     FRQLIAQSREGKIHALQIATESSIRSMQEQSKRLVTGKLKEVAYQKIDEQTEALVSMI
                     GDNQVDYRFFLGFKLMVTEEQLNLKNLKKSAWLTFKEFLHEVNHTLMNDFVSMPNDEI
                     NRYMKMEKLLENKISRRFKVRRLEINDFGYLMEHLYGRDGIAYEDYEHQLPKKKYKKE
                     TLIKYYDLIRPTRCVIEESQRYLRLEHEDKESYVSYFTVNAIVGELDFPSSEIFYFQQ
                     QQFTFPVDTSMNVEIVENRKALTTVRNKKKELKDLDNHAYQAGSETSSNVVDALDSVD
                     ELETDLDQTKESMYKLSYVIRVSADDLDELKRRCDEVKDFYDDLNVKLVRPAGDMLGL
                     HSEFLPASKRYINDYVQYVKSDFLAGLGFGATQQLGENTGIYMGYSVDTGRNVYLQPS
                     LASQGVKGTVTNALASAFVGSLGGGKSFCNNLLVYYSVLFGGQAVILDPKSERGNWKE
                     TLPEIAHEINIVNLTSDKDNAGLLDPFVIMKNVKDAESLAIDILTFLTGISSRDGEKF
                     PVLRKAVRSVTQSETRGLLHVIDELRCEDTAISRNIADHIDSFTDYDFAHLLFSDGTV
                     ENAISLDNQLNIIQVADLVLPDKDTTFEEYTTIELLSVSMLIVISTFALDFIHSDRSI
                     FKIVDLDEAWAFLNVAQGEILSNKLVRAGRAMQAGVYFVTQSSGDVSKESLKNNIGLK
                     FAFRSTDINEIKQTLEFFGIDKEDENNQKRLRDLENGQCLLQDLYGRVGVVQIHPVFE
                     ELLHAFDTRPPIQRNEVE"
     gene            complement(5522..5911)
                     /locus_tag="OE968_002007"
     CDS             complement(5522..5911)
                     /locus_tag="OE968_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009274602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HCP7219286.1"
                     /translation="MKKIRSYTGIWNVEKVLYAINDFNLPFPVTFTQITWFVITEFII
                     ILFGDMPPLSMIEGAFLKYFGIPAFLTWFMSQKTFDGKKPYSFLKSQITYALRPKITY
                     AGKAVKLQKEIFNETITAVRSVSYVPD"
     gene            complement(6029..6532)
                     /locus_tag="OE968_002008"
     CDS             complement(6029..6532)
                     /locus_tag="OE968_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004843360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HCP7219287.1"
                     /translation="MIDDMAVYIANLGKYNEGYLVGAWFTFPIDEEDVKEKIGLNEQY
                     EEYAIHDTDNFPIEIGEYVSIDELNEMYEMIEELPDYIVDCLDEFIGHYGTLEEVVEH
                     KDDIYYYPDCETMTDVAYYYIDELQALGDIPPSLQNYIDYEAYGRDLDMGGCFIATSR
                     GMCEIPY"
     gene            complement(6535..7038)
                     /locus_tag="OE968_002009"
     CDS             complement(6535..7038)
                     /locus_tag="OE968_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004843359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HCP7219288.1"
                     /translation="MQETRVLVETKRTTGEETTSYWFDLPIEVAEFEEKLGVSTESQD
                     YRIIEKLLPYADEVHEHTSVYQLNELDYMYRQLSSDMQEEYTMLHTVYENLEALYICR
                     NVITLYPDCKSMIDVARQKLMNDPTFKHLSEDCQEYYFDFETYASHLQEHGKFLVTEH
                     GIFELPE"
     gene            complement(6957..7253)
                     /locus_tag="OE968_002010"
     CDS             complement(6957..7253)
                     /locus_tag="OE968_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005339688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HCP7219289.1"
                     /translation="MNDIFRDMQAKVGCENISDLPSYKRKVWHEMKQLNLADYEEKQL
                     EDFSKYVFGMSCQTLKDVMKQQKGREEQCRKQGYWWKRKEQLAKKQHHTGSTCR"
     gene            complement(7350..7952)
                     /locus_tag="OE968_002011"
     CDS             complement(7350..7952)
                     /locus_tag="OE968_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HCP7219290.1"
                     /translation="MDKVVIYIHGKGGNAEESSHYKPLFSDCDVVGLNYTAQYPWEAK
                     EEFPSLFDLICKHYKSVQIVANSIGAYFAMNALSDKQIEKAYFISPIVNMEKLIADMM
                     YWANVTEDELRDKKEIKTTFGETLSWEYLCYVKENPTTWKIPTNILFGEKDNLTSYAT
                     ISEFTKQTNATLTVMRNGEHWFHTEEQMKFLDEWINKSAR"
     gene            complement(8037..8198)
                     /locus_tag="OE968_002012"
     CDS             complement(8037..8198)
                     /locus_tag="OE968_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219291.1"
                     /translation="MAIVVIGIYLGFKREFSKLIGFLVVALVAVGLVFNAGGVKDVLL
                     ELFNKIIGA"
     gene            complement(8365..10275)
                     /gene="ltrA"
                     /locus_tag="OE968_002013"
     CDS             complement(8365..10275)
                     /gene="ltrA"
                     /locus_tag="OE968_002013"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HCP7219292.1"
                     /translation="MPKNKNETLCVEDLRHAEYYEMQNTFDDLYAKSKNGDIFTHLMD
                     IILSRENILLAYRNIKANAGSKTAGTDGTIIKDIGKLPAETVVKKVRYIVAGSPHGYR
                     PKPVRRKEIPKPNGKTRPLGIPCMWDRLIQQCIKQVLEPICEAKFSENSYGFRPNRSV
                     ENAIKATYNRLQISQLHYVIEFDIKGFFDNVNHSKLIKQIWAMGIRDKHLIFILKRIL
                     KAPIKMTNGTITYPEKGTPQGGIISPLLANIVLNELDHWVESQWQENPVTKNYVVHIN
                     KSGSPCKSNAYKEMKKTKLKEMYMVRYADDFRVFCRYKESAEKAKIAITQWIEQRLKL
                     EVSQEKTRIVNVRKRYSDFLGFKIKMIPRRKKLVVKSHISDKQFKNQKDKLVSQAKKI
                     ASPSKGKTELEETRLYNSMVLGMQNYYQIATNVNLDCMKLNRAVMAIFTNRLGTNKRG
                     RLRKTGRQLTTKEATRYGKSKMLRYVAGEGEPIFPVGYIQHRKPMAKVYLANCYTLEG
                     RKFIHTNLSVDKLLMYQLMKLSLENRTIEYADNRISLFSAQHGKCAITLEEFQQANEI
                     HCHHIVPTGAGGNDDYKNHILVKEAVHRLIHAKTEETIQKYIALLKLNKVQLIRLNKY
                     RVLAGNQELNLI"
     gene            complement(11017..11151)
                     /locus_tag="OE968_002014"
     CDS             complement(11017..11151)
                     /locus_tag="OE968_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017143882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HCP7219293.1"
                     /translation="MWELLKDLLLVSFGMGIGVVLMCILTVGKEADRCMEEIKEREDN
                     "
     gene            complement(11159..12358)
                     /locus_tag="OE968_002015"
     CDS             complement(11159..12358)
                     /locus_tag="OE968_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HCP7219294.1"
                     /translation="MNETDFLTALKEKRCAYGVSQTRLAIMANISREHLSRIEAGKVT
                     LTEDMKHTLLEAVEKFNPNNPMFLLFDYVRIRFPTMDIKHIIKDILKLNIGYMLHEDY
                     GHYKYTEHYHIGDVFVYVSQDEEKGVLLELKGKGCRQFESYLLAQERSWYDFFTDALV
                     EGGVMKRLDLAINDRTGLLDIPELIRKCENEECISKFRSFKSYGSGELVKHNETDKYG
                     MGHTLYIGSFSSEVYFCCYEKNYEQYAKLGIPIEEVPIKNRFEIRLKNERAYYAVVEL
                     LTHYDAELTAFSIINQYIRFADKEPDKRKSDWKTNVRWAWFIGEGRPPVKLTTQPEPY
                     TLERTLNWLQRQVAPTLKMLKQIDKDNQTEYLETIEKQAKLTERHYQIIKQQTATVEE
                     MVANVKE"
     gene            complement(12560..13954)
                     /locus_tag="OE968_002016"
     CDS             complement(12560..13954)
                     /locus_tag="OE968_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008787614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HCP7219295.1"
                     /translation="MKMILNKGHRIRASDKNLVYHFSIGTLLFVFIAVILLLNMKQLM
                     RTDWEHFSLLDNGLTLSTYNFITLLIATGVCALVAFLYYRFCYDSFKKLLHRQKLARM
                     ILENKWYEADTVQDSGFFTDLQSRSREKIIWFPKIYYQMEKGLLHIRCEITLGKYQDQ
                     LLRLEDKLESGLYCELTDKTLHDGYIEYTMLYDMIANRITIDEVKAENGCLRLMKNLV
                     WEYDALPHALIAGGTGGGKTYFLLTLIEALLHTNAVLYILDPKNADLADLGTVMGNVY
                     HTKEEMIDCVNAFYEGMVQRSEEMKRHPDYKTGENYAYLGLPPCFLIFDEYVAFFEML
                     GTKESVSLLSQLKKIVMLGRQAGYFLIVACQRPDAKYFSDGIRDNFNFRVGLGRISEL
                     GYGMLFSSDVKKQFFQKRIKGRGYCDVGTSVISEFYTPLVPKGHDFLQTIGSLAYARQ
                     DGTATCEAKGDGTD"
     gene            complement(14071..14556)
                     /locus_tag="OE968_002017"
     CDS             complement(14071..14556)
                     /locus_tag="OE968_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006776881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219296.1"
                     /translation="MAKEKGSFKEFLSAIAPEHQAFVEKLNTKLIEQGCDLVIKEAKS
                     GYTASYQLEKKTVMNWVFRKTGVFARIYGDNAGKYEDIIASLPADMQKKMTTSRDCKR
                     LIDPNACSDTCVKGFVYALNGDTHKKCRNDGMLFVLTNETAEHIAGLVCAEVNVRKSA
                     L"
     gene            complement(14654..15037)
                     /locus_tag="OE968_002018"
     CDS             complement(14654..15037)
                     /locus_tag="OE968_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014080829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HCP7219297.1"
                     /translation="MRLANGIVLDKEKTFGVLKFSALRHEVRAENDDGSTSEEITRRT
                     YDLKCSVQERMIQVSIPADIPVKDYPYNAEVELVNPVADTVANASYRGVNVDWYIKAD
                     DIILKNKGGQVGNPQNHAPQGQPKK"
     gene            complement(15052..15378)
                     /locus_tag="OE968_002019"
     CDS             complement(15052..15378)
                     /locus_tag="OE968_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005337695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HCP7219298.1"
                     /translation="MELKYVVPNMAQTFGNLEFAGENKIEQQRINGRFTPVSRSYNLY
                     SDVQRADDIIVTIPAKAGEKHFKPEQRVKLINPKITADGKAVKGRGFTNYILTADDML
                     PAEESK"
     gene            complement(15614..18658)
                     /locus_tag="OE968_002020"
     CDS             complement(15614..18658)
                     /locus_tag="OE968_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SrtB-anchored collagen-binding adhesin"
                     /protein_id="HCP7219299.1"
                     /translation="MKKILKRLCTGVLAFATVVTALPTTLVHAESKQYWTESEERVGI
                     VEKVMNDGSIGSTFNEGHLTVEGEDAYCIDINTDFKNGYKTRADASSRMSADQISDVA
                     LSIEYVKQYTDNHNGISKNHAYLLRQLVVWQRLSVHLGWQCDNVRASYDEIPKATQDE
                     VFAGAKAFVKENKGRYECGGYIYSGEGQELGQFWAKLNVGNAKLQKTSNNTSITNGNG
                     NYSIAGATYGVFSDKDCTKQIATLTTDDSGNTEVAEVKATTVYIKELSAPLGYKVDTT
                     VYSLKVEAGKTATLKVSDTPKVTDTLIELFKIDMETQKANPQGNASLEGAEFTWKYYA
                     GFYNKDNLPAEATRTWVTKTTAETDSNGTTHYITKLADAYKVSGDSFYMQDGKAFLPL
                     GTLTVEETKSPTGYLLDGAYMQANGSEEQIKALYLTQITEDGDLAVLTGSNQFSVSDK
                     VIRGGVKIQKRDLETKDTKPQGSATLKDTAFDIISLNDNAVLVEGKIYKKNEVVKTIH
                     TDIEGIASTSADLLPYGNFRIVEKQAPNGYLTDGAKPIDFTITENGKIVDLTDEAHSI
                     YNQIKRGDIEGVKIGAGTHKRLADVPFRITSKTTGESHVVVTDDNGQFSTSSKWASHK
                     HNTNAGKTSEDGVWFGTSEPDDSKGALPYDTYIIEELRSDSNKGMELIPPFEIVVSRN
                     NLVIDLGTLTDEYEKEITIHTTATSKDGEKTILAGKEVTIVDTVKLDGLTKGTKYQLK
                     GWQMLKEENAEIIIDGKRVESDYTFVADDEEMKVEISYTFNASELGGKNLVTFEELYD
                     LSNPDEPMKVAEHKDIEDDGQTVLITERIIKIHTTATDKDGNKELEAGKDVTIIDTVT
                     LEGLEVGTKYKLVGWQMLKEENAELLINGKRVESDYTFIADSETMKVEVTFTFDATSL
                     DGKQLVTFEELYDLSNPNEPKKVTEHKDIEDEGQTITFKEKPEVPEKPETPTTPEKPS
                     RPTDSPKTGDNTNVMAFLVMLLTSAGGLAGTYLYKRRKMKKS"
     gene            19186..20193
                     /gene="asrA"
                     /locus_tag="OE968_002021"
     CDS             19186..20193
                     /gene="asrA"
                     /locus_tag="OE968_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic sulfite reductase subunit AsrA"
                     /protein_id="HCP7219300.1"
                     /translation="MKLKLDSSKFNEGLNYLKKDYKIFAPVLIPFKGTFSDTDVIRYK
                     EVNAFEEMEFAKKANFSPKDVVLPINQVLFYFTEKEFKESDLDNKKILIFLRACDING
                     IKRLDEIYLNNGEEKDYFYKNIRDKVKFALVGCKESFRNCFCVSMDSNKTDNYSIGLN
                     IEGDTLYLDIKDSEFEVFNGEATEFNVDYVTDNLISVDVPENIDSNEMIGNSIWDEYD
                     TRCIGCGRCNFVCPTCSCFTMQDIFYKENENVGERRRVWASCQVDGYTDIAGGNSFRK
                     KQGERMRFKTMHKIHDFKKRFGYHMCVGCGRCDDACPQYISFSKCIEKINDLVISKEE
                     V"
     gene            20194..20985
                     /gene="asrB"
                     /locus_tag="OE968_002022"
     CDS             20194..20985
                     /gene="asrB"
                     /locus_tag="OE968_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic sulfite reductase subunit AsrB"
                     /protein_id="HCP7219301.1"
                     /translation="MNPYIPVSAKILDIVKHTDKEWTFRVNCNTKGVLPGKFYEISIP
                     KYGESPISVSGYGEDYIDFTIRNVGKVTSELFNYKEGDSFFIRGPYGNGFDVSLYEGR
                     EIVVVAGGSALAPVRGIVEYFYNNKEKCEKFKLIVGFKSPKDILFADDLKRWSKKLDI
                     LVTVDGAEEGYSGNVGLVTKYIPELDMKDINNTSIVVVGPPMMMKFTVEEFLKRDLDE
                     KNIWVSYERKMCCGIGKCGHCKMDDTYICLDGPVFDYSYAKNLID"
     gene            20998..21969
                     /gene="asrC"
                     /locus_tag="OE968_002023"
     CDS             20998..21969
                     /gene="asrC"
                     /locus_tag="OE968_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite reductase subunit C"
                     /protein_id="HCP7219302.1"
                     /translation="MIRDLNTKKVMKNAYRITKTKYETSLRVRVPGGLIDPESLAVVS
                     KIASEYGNGQVHITTRQGFEILGINMEDMEEINKIIQPVIEKMNINQSEKNAGYPAAG
                     TRNIAACIGNKVCPKAQYNTTEFAKRIEKAIFPNDLHFKVALTGCPNDCIKARMNDFG
                     IIGMALPIYEKDRCVNCGACVKKCSKISVGALKTENNKVVRDKDKCIGCGECVLNCPT
                     NAWTRDEKKYYRLAIMGRTGKKNPRLAEDFLLWVDEDSIIKIILNTYRYVEKYIDKDA
                     PGGKEHIGYIIDRTGFMEFKKWALEGVELPEITKMYENIYWSGIKYL"
     gene            22026..22802
                     /locus_tag="OE968_002024"
     CDS             22026..22802
                     /locus_tag="OE968_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HCP7219303.1"
                     /translation="MHKETLDKLTNAAINKINLLNTSKVKYLVSSAFAGLYVGIGILL
                     IFTIGGLLTDAGSPMTKIVMGLSFAIALSLVIMTGTELFTGNNMVMSAGMLNKGVSIK
                     DTSKIWAYSWVGNLIGALVLGIIFVGTGLVDKGPVAEFFANTAASKASMPFTALFFRG
                     ILCNILVCVSVLCSFRTNSDTAKIIMIFLCLFAFITSGFEHSVANMTIYSVSLFSPTI
                     STVTIGGAIYNLVAVTLGNIVGGALFMGLGTYILGKEKLN"
     gene            23073..25091
                     /locus_tag="OE968_002025"
     CDS             23073..25091
                     /locus_tag="OE968_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HCP7219304.1"
                     /translation="MTKKLVISKTKLFIFIIAFISIFIYLFGSKNTLIGVGIVTAMLT
                     LLERDLTISPIKNLLKYLAINIILGILSFFAVQNMYLGVLLNFIALFIIGYVFSYDLK
                     RAVYVPFGLMYIFMVSIPVGKSEFPMRLSALAVGAVIIMIAQFVMNRNRMKNVGDKEL
                     ISICDELLEKISLLKNTINDDSSIIKSSMRKIDSCNYRINSISKNLKMVIFDNRKDDF
                     YISIRGIDIMNILFSLERISLILERYKKDSKEFEDEDIKNILEESSINSKSDVLVVAT
                     KEINYIKMCLENKDTITDKEILGFRDYVIAQDTKNINLKEIYSVLENLYEFLVDYKKV
                     KSRDEKKAERKSKIPHEFKRLSIYKKNFNLNSIRFSYAVKIALATAVAGFIMDYFHLR
                     DGRWIMLTVFSLTQPYAENCIQRSRKRIEGTFIGAVIFIVLFSIIKDSTLRSLIVLLA
                     GYINSYVVDYRKLMVCVTVSALGSAVVMGDPNVLTISRISYVALGAIIALIVNKFILP
                     YDAKTGYQHVIEMYKGIVKNIIDEVNKSIENVADVYYIKNLLLIPSLIEDRLMLINAI
                     YKDKHQEDFLENQKLLISNMYNLYINVNKNKIKDEDVEKILRDTNYISNYNVDKYDEG
                     RSVILESIVNTKSLGDKIICLNLLQTLNGVKEMYRISNITKVSIKEAA"
     gene            25306..26163
                     /locus_tag="OE968_002026"
     CDS             25306..26163
                     /locus_tag="OE968_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HCP7219305.1"
                     /translation="MSKDVKVKRNKKYDTFSITMELERPLLYDEVENKDDKNNNRKFN
                     IKNKIFKGIGILFVLILLGFFIWINKTYEPQKLAKEALVSNSKVEVTVNENISFTPKG
                     RKVSKGLILYPGAKVEIESYAPLARKIAESGYEVVIVKMPLNLAILGTNKAQKVMDSY
                     NNIEHWVIGGHSLGGVAASNFARDNKLIEGVVFLASYPMGDELKELGKKVISIWGSKD
                     GVVNFKSLVESKQKLPDDTTYVEIEGGNHAQFGDYGKQKGDNDAIISQEKQLNITANS
                     IIKFLKNIS"
     gene            26260..27129
                     /locus_tag="OE968_002027"
     CDS             26260..27129
                     /locus_tag="OE968_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HCP7219306.1"
                     /translation="MEYDMPLYRPPSEAYSLIIQVTLGCSHNKCTFCSMYKSKKFKIK
                     PLEVIKNEIDIFRRYYKHVERIFLADGDALIIPMEKLRDIILYIKEVFPECERITMYG
                     SPKSIEKKSDDELKELRKLGVKMIYLGLESGSNEVLEDIKKGFSSEQLIKVGRKVKKS
                     GIKLSATVIAGLGGTKKTHQHAVDTGKMLGAISPDYVGVLSLMVEPNTELYDLLKAGE
                     FTILEDKAVLQEIKEMIKNIDANEKIVFRSNHASNYANLKGVLPDDKQRLIDEIDYYL
                     SNQKLKREEYRRL"
BASE COUNT         8308 a         5032 c         5025 g         8991 t
ORIGIN      
        1 attcccacat gggtaacata cgaaccagcg ttataggttg aatggaaaaa gaccaactcc
       61 ccagcttttg cctgcgataa agggatatgc tgggttgcgt catattgcat ttgtgccgtt
      121 ctcggtaaag agataccagc ttttccataa caccattgcg tcagtcccga acagtcaaag
      181 gaagtgttgg gattgctacc gccatacaca tatttccagc cttgatattt caacgcttca
      241 ttcattacct tttgtgccag ttctcccgat acctgcggaa cagttaaata ctgattgact
      301 aattccacat aaaacatatt tccatagcca taccgccagc ccccattttt cgcaacggct
      361 atcgggttgg tgtaggttac ttttttaccg ccagatttct cacgggcaaa gctctctgca
      421 aggttaaaag tatgtttctt tccttttcct gccacatatc ccacatagcc accgccatag
      481 ttataggact gtatcgccac attcaaatca tttattcctt gatttttgca ggaagaaagc
      541 agggacgcaa aatatttaca cccctgcttg attgagcttt ctgtatctaa cgagttgggc
      601 ggtaaaccaa gactttctga actctgcatg acatcttttg ccgtaccgcc actttctact
      661 tgaatgatag ccagtaacac attcacatac tcagaaatac cgtattcttt agcgtacttt
      721 tccaccatag gctgatgttt caagacttct gcggataaat tcatacccgt aatgcccgaa
      781 gaaaagttgc tgttctcgtc gtcgctgtcc gcactcatca gtaccccaaa gaaaaggact
      841 atggaaaaga ggataggaaa cagactgcca atgatagcga tatgtttcaa tttcattttt
      901 tcttctgtcc tttcttcgtt acaaggttac ggttcttttc agtatgttct gttgtacgct
      961 ttgcttgttc aactgtttgt gcctttgtgg tacgttctgc tttgtaattc tggtgtgttt
     1021 catgcgatac cactttttct acatttttac tatgtactgt ctgtgccgat tgtggaattt
     1081 ttccgtcaga tgtacccgaa gataagggac gttctttcac actatttgtt ttgactggct
     1141 cgcctgcttt ggaagttgaa gttgtagcag gacgtttgac ttcctgtgtt ttctcaacat
     1201 ttgtttttgg aatggctgaa gctgtgactg gtcgctcatg gggacgggta gctcccgttg
     1261 tcgctgatcc gtccgtcttt cgtgcctgcc ttgcttcttg tgctttttga agttccatac
     1321 gcttgtcagc gatattcttc ttatgctgtt cctgcttttc caagcgtccc gactgtctgg
     1381 attgttgttc ctgcaccatg ccacgcttga agtccgatac acttgttttt gctttttcct
     1441 ttgcggaatg gacggcataa gcggtctgtg tcggtatatc cttgaccgtt tctttcatag
     1501 cgtttgcctt gtctttgacc ttattcttcg tatctaagac agcacccacc tttgaaccag
     1561 cacgttgtcc catgctggaa gatgtattcc ctcggttgtc ttttgctgaa ttattccttg
     1621 ttgtccttgc attagaaacc gtactgccag ccaccgcacc agcaacaccg ccagcggtaa
     1681 cagcaccagc aagccgtctt tccatacgcc tagccctatg tgccatataa agatacggtc
     1741 tgcggaaaat tcttcgtccc atgctttgac tgtcgttagc gttcaaagag aacatactca
     1801 ttaaatcgcc taacttcatg tagataccag cgaaacacac tatctgcaag aacgccacca
     1861 taaagaacgg gtagtctgtg gaaatgttat aaaacatact ggaaatgcta aatgccaccg
     1921 ttacaatgag cgtaattcct gcccttgtca ttatggtatt aaataccctc acgattgcct
     1981 gctttgccat gctttcatag ctcggtatca tggatagtaa aaagctgata ggtaaaaaca
     2041 tggcgaagat aataaaaagt atctggctga acaacatcat acccgtaagc aagaatacaa
     2101 atatcgtgat acctaagttg aagaacaaga ggaagaacac catacctaaa cggtttacga
     2161 cttgcggtat cgtcagattg ttgttgtcgt tactttcgat ttctgttttc acgacttcct
     2221 ctctggtttt gccgtcctcg ttctctgggc ttgccgatac aagagcttct acacggtctg
     2281 tcccgatttc ctctgcgttg ctgttcccaa actgtaagag tagccacggc tgttccactt
     2341 gaatagagaa taggctgtcc cttatcaagt ccacgctgtc cttgccctcg ctgtcagagt
     2401 ttgggagcat gatttttgtt cccaagtcca aagaagcggt actgatgtcg cttgaaaatt
     2461 catttatctt tttgatgtag tcgggagcat aggcaataaa tgaagccgac aaaataaaca
     2521 ccacaacaaa gttgataacg gcgtgaagtg ccttgctggt ttctctttta atcagtcccg
     2581 tataggcaac atatagtccc accactaaga taatgagaag caggaaaccg acatagaagc
     2641 cagaggttga aaaaccgctt gaggtaacgc ctgcaagggt ctgtatgctc tgcccgatac
     2701 tgtctgccat atcattgatg aagtccagct tgtaggcttc ctgcactaca tagcccgtgg
     2761 cattacttaa atataaactg atagtccaga caaaattagt gatacagtac aaaccatatt
     2821 gtactgattt tccaatcccg tccagccagt tccacggcaa ccaagcccag ctattatcca
     2881 catagaagtc aagctgatag ttggaaagcg gatatttgga atatagattt tctgcgttta
     2941 tcgtatcgtc cacaagcccc gtcgcatgag ccaccgtccc cagaagtgaa agcaggataa
     3001 gggagagtgc caccacgaac agagccattt tgagaaagtg gaaaatcttc ttttttgtga
     3061 acgcactctg tatcctttct ttcatcactc cacctcattt ctctgtatag gcggtctggt
     3121 atcaaaggcg tgtagcagtt cttcaaagac ggggtgtatc tgtaccacgc cgacacgccc
     3181 gtataagtcc tgcaacaagc attgtccgtt ctccaaatca cgaagtcgct tctgattgtt
     3241 ttcgtcctct ttgtcgatac cgaaaaattc taaagtctgt tttatctcgt tgatgtcagt
     3301 agaacggaaa gcgaatttta agccgatatt gtttttcaga ctttcctttg acacgtcccc
     3361 agaagattgc gtaacgaaat acacacctgc ctgcatagct cgtccagcac gcaccagctt
     3421 gttagataaa atttcgcctt gtgccacatt taagaacgcc cacgcttcat caaggtctac
     3481 gattttgaag atagagcggt cgctgtggat aaaatctaag gcaaaggtac taatcacaat
     3541 cagcatggaa accgatagta attcaatggt cgtgtattcc tcaaaagtcg tgtccttatc
     3601 tggcagtaca aggtcggcta cttgaatgat attgagctga ttatctaaac tgatagcatt
     3661 ttccaccgtt ccgtctgaaa acagaagatg tgcaaaatca tagtctgtaa agctgtcgat
     3721 atggtctgcg atattgcgtg aaattgcggt atcttcacag cgtaactcgt ctatcacatg
     3781 aagcaagccc cttgtttcac tctgggtaac agaacgcacc gccttacgaa gtacggggaa
     3841 tttttcgccg tccctagagg aaataccagt taaaaaggtt agtatgtcga ttgccagact
     3901 ttcagcgtct ttcacattct tcataatcac aaacgggtca agaagccctg cgttgtcctt
     3961 gtcgcttgtt aggtttacga tattgatttc atgggcgatt tctggaagtg tttctttcca
     4021 gtttccacgc tctgattttg ggtctaagat aaccgcttga ccgccaaaca aaacagaata
     4081 gtacacaagc aggttattac agaatgactt cccaccgcca agcgaaccaa caaaagcaga
     4141 agcaagggca tttgtaactg taccttttac gccttgactg gcaagggacg gttgcagata
     4201 tacatttctt cccgtatcaa cggaatagcc catatagata cccgtgtttt cccctaactg
     4261 ctgtgtcgca ccaaaaccaa gcccagctaa gaagtctgat tttacatact gcacataatc
     4321 attgatatat cgcttgctgg ctggtagaaa ttcagaatga agccccagca tatccccagc
     4381 aggacgtact aacttcacat tcaaatcgtc ataaaaatct ttgacttcat cacaacggcg
     4441 tttcagttcg tccaaatcat cagcagacac acggataaca taagagagct tatacatact
     4501 ttcttttgtc tggtctaaat cggtttccag ctcgtccacg ctgtctaaag cgtctactac
     4561 atttgagctg gtttcacttc cagcttgata agcgtgatta tcaaggtctt tcagttcctt
     4621 tttcttgttg cggacggtcg ttaatgcttt tcggttttcc acgatttcta cattcatgct
     4681 cgtatcaacg ggaaaggtaa attgctgttg ctggaaatag aagatttcac tagacggaaa
     4741 atcaagctcg cctacaatcg cattgacggt aaaataggac acataacttt ccttgtcctc
     4801 atgttccaat cgtaaatatc gctggctttc ctcaatcaca caccttgtcg ggcggataag
     4861 gtcgtaatac ttgataagtg tttctttctt atactttttc tttggtagct ggtgctcata
     4921 atcttcatag gcgataccgt ccctgccgta aagatgttcc ataagatacc caaagtcatt
     4981 gatttccaga cggcgaacct taaagcgacg ggagatttta ttttccagta acttttccat
     5041 tttcatgtaa cggttgattt catcattcgg catggaaaca aagtcgttca tcagcgtgtg
     5101 gttcacttca tggagaaact ctttgaacgt cagccacgcc gattttttaa ggttcttcag
     5161 attgagctgt tcttccgtaa ccatgagttt aaagccaaga aaaaagcggt agtccacttg
     5221 attgtcccca atcattgata ctaacgcttc ggtctgttcg tctatcttct ggtaagcgac
     5281 ttcctttaat ttccccgtaa ccaatctttt tgactgctcc tgcatacttc ttatagagct
     5341 ttccgtggca atctgcaaag catgaatttt accctcacgg gactgtgcga ttagctgtcg
     5401 gaaactgtca tgcacgataa atttctgttc tgcggataag aaagaatagt tatacggtat
     5461 cagctcatag taggcgaaca cctcattgtc cttgttccag acaaggttgt tgtcaatata
     5521 tttaatcggg aacataactc acactcctta ctgccgtgat tgtttcgttg aatatttctt
     5581 tttgcagttt tacggctttt cctgcataag tgattttcgg tcgcaacgca taggttatct
     5641 gtgatttcaa aaagctgtat ggcttctttc cgtcaaaggt tttctgcgac ataaaccaag
     5701 tgaggaaagc aggaataccg aagtatttta aaaatgctcc ctcaatcatg gaaagtgggg
     5761 gcatatcccc aaacagaatg atgataaatt ctgtaatcac aaaccatgta atctgtgtaa
     5821 aggtaacggg aaagggcaag ttaaagtcat tgattgcata caagactttt tctacattcc
     5881 agatacccgt gtagcttcta atctttttca agttctttca actcctctca taagtttcta
     5941 aatggaaaag gacagccctg tttcagactg tcccttaaag agaaatacgc cgtcagtagc
     6001 aacaatgctt gtcgctgatc ttccagcgtt aatatggtat ctcgcacatt cctcggcttg
     6061 ttgcaatgaa gcaaccgccc atatccaaat ctcgcccgta tgcttcatag tcaatatagt
     6121 tctgcaagct agggggaata tcgccaagtg cctgcaattc atctatgtag taataggcaa
     6181 catctgtcat ggtttcacag tcgggataat agtaaatatc gtccttgtgt tccacgactt
     6241 cctccagcgt cccataatga ccaataaatt cgtccaaaca atccacgata tagtcgggaa
     6301 gttcctctat catttcatac atttcattga gttcatcaat ggaaacatac tccccaatct
     6361 caatcgggaa gttatcggta tcatggattg cgtattcttc atactgttca ttcaagccga
     6421 ttttttcttt cacatcttcc tcgtcaatag ggaaagtaaa ccaagcaccg actaaatagc
     6481 cctcattata cttgccaaga ttagcgatat aaactgccat atcatcaatc atacttactc
     6541 tggcaattca aagataccgt gttccgttac taaaaatttc ccgtgttcct gcaagtgtga
     6601 agcataggtt tcaaagtcaa aatagtattc ttgacagtcc tcggataaat gtttgaatgt
     6661 agggtcattc atcagctttt gccttgcaac atcaatcatg cttttacagt cgggataaag
     6721 cgtaattaca ttcctgcaaa tataaagtgc ttctaaattt tcatacaccg tatgaagcat
     6781 tgtatattct tcctgcatat cgcttgaaag ctggcgatac atataatcta attcattgag
     6841 ctggtacacg cttgtatgct catggacttc atcagcataa ggcaacaatt tttcaataat
     6901 gcggtaatct tgactttctg tactgacacc taacttttct tcaaactcgg caacctctat
     6961 cggcaggtcg aaccagtatg atgttgtttc ttcgccagtt gttcttttcg tttccaccag
     7021 tacccttgtt tcctgcattg ttcctcacgt cctttctgtt gtttcatcac atcttttaaa
     7081 gtctggcatg acataccaaa cacatatttt gaaaaatctt ctaactgttt ttcttcatag
     7141 tcggcaaggt tcagttgctt catttcatgc cacaccttac gcttgtaaga gggcaggtct
     7201 gaaatgtttt cacaaccaac ttttgcctgc atatctctaa aaatatcgtt cattacatca
     7261 ctccaatctg aaatttaggt aagaaaaaag cagtcaatcc taagactaac tgctttgtgt
     7321 gtatggatat gaagttgtca aactgggatt tatctggcag acttgtttat ccactcatca
     7381 agaaatttca tttgttcttc cgtgtgaaac caatgctctc cgtttctcat aacagtaagt
     7441 gttgcattag tttgttttgt aaattcagat atagttgcat aagaagtcaa gttatctttc
     7501 tcaccaaata aaatatttgt tggaattttc catgtagttg gattttcttt tacataacag
     7561 agatattccc atgagagtgt ttctccaaaa gttgttttaa tttctttttt atctcgaagt
     7621 tcatcttctg taacatttgc ccaatacatc atatctgcaa tcagtttttc catattcaca
     7681 ataggtgaaa taaaatatgc tttttctatt tgcttatctg ataaggcgtt catagcgaaa
     7741 taggcaccta tgctatttgc aactatttga acagatttgt aatgtttgca aatcaaatca
     7801 aaaagtgatg gaaattcttc ttttgcttcc catggatatt gtgcagtata gttgagtcca
     7861 accacatcac aatcactaaa aagaggtttg taatgtgaag actcctctgc atttccacct
     7921 ttaccatgta tataaataac tactttatcc ataatagttg tcctcctcaa cttcaaattt
     7981 gtcgctttct tcatatccac attatatcat tctcatatca gcaccacaat aaaattttac
     8041 gcaccgataa tcttattgaa cagctctaac agtacgtctt tcacaccgcc agcattgaat
     8101 accaatccaa cggcaacaag ggcaactacc aagaagccga taagtttaga aaactcacgt
     8161 ttgaacccta agtagatacc aataaccaca atcgccataa gcactaagct ctgggcgttg
     8221 cttaaaaacc atgtgtatat ggataggtaa gttcctgata ttataaatat ctcaaacttt
     8281 tccccccatt cacacggagc gtgcgacttt caacgcactc cgcgttccat cgtgtttata
     8341 ttgaaaagta tttatgtagt agacctatat caagtttaat tcttgattgc cagctaatac
     8401 tctatattta tttagtctta tgagctggac tttatttagc ttcaatagag ctatatattt
     8461 ttgtattgtt tcttctgttt tagcgtgtat tagacggtgt accgcctctt ttaccaaaat
     8521 atgattttta taatcgtcat ttccaccagc tccagttggt acaatatgat gacaatgtat
     8581 ttcattagct tgttgaaatt cttccagagt tatagcacat tttccatgtt gagcagaaaa
     8641 tagcgaaatt cgattgtctg cgtattctat tgtgcgattt tccaaagata atttcattaa
     8701 ctggtacatc agtaatttat caacacttag attggtgtgg ataaattttc ttccctctag
     8761 agtgtagcaa ttcgctaaat acacctttgc cattggtttt ctgtgttgga tatatccaac
     8821 agggaaaata ggttcgccct cgccagcaac ataccggagc attttagatt taccatatct
     8881 tgttgcctcc tttgtcgtaa gttgtctgcc tgtttttctc aatctgcccc ttttgtttgt
     8941 acctaatctg ttagtgaaga tagccattac agctctattc agtttcatac aatccagatt
     9001 tacattcgtt gcaatctgat aataattttg catacctaat accattgaat tataaagtct
     9061 tgtttcttct aattccgttt tcccttttga gggagaagca attttctttg cctgtgatac
     9121 cagcttgtct ttttggtttt tgaattgttt atcacttata tgtgatttaa caactaactt
     9181 ctttcttctc ggtatcattt taatcttgaa accaagaaag tcggagtatc tttttctaac
     9241 atttacaatt cttgtttttt cttgtgatac ttccaatttt aatcgttgtt caatccattg
     9301 agtgattgct attttggctt tttcagcact ttccttgtag cggcagaaaa ctctaaaatc
     9361 atctgcataa cgaaccatat acatttcctt taactttgtt ttcttcattt ctttgtaagc
     9421 gttgctttta catgggctac cgcttttatt gatatgaacc acatagtttt ttgtaacagg
     9481 attttcctgc cattggcttt ctacccaatg gtctaactca ttaagaacaa tgtttgctag
     9541 tagtggggat attattcccc cttgcggagt tcctttctct ggatatgtta ttgtaccgtt
     9601 agtcattttg attggagctt ttaatatcct ttttaaaatg aatatcaagt gcttgtcccg
     9661 tattcccata gcccatatct gttttatcag cttggaatgg ttcacgttgt caaagaaacc
     9721 cttaatatca aattcaatca cataatgtag ctggctgatt tgtaggcggt tataggttgc
     9781 ttttattgca ttttcaactg acctattagg tctgaaacca tagctgtttt cactaaattt
     9841 agcttcgcag attggttcta atacttgttt tatacattgt tgtataagcc tgtcccacat
     9901 acaaggaata cctagaggtc tggttttacc atttggtttt ggtatttctt ttcgcctcac
     9961 tggcttaggt cgatacccat gtggactgcc tgcaacaatg tatcttactt ttttgacaac
    10021 tgtttctgct ggcaatttgc caatatcttt aattattgta ccgtctgttc ctgctgtttt
    10081 actgcctgca tttgctttga tatttcgata tgccagtaat atattttctc tcgataggat
    10141 aatatccata agatgagtga aaatatctcc attcttactt ttggcatata aatcatcaaa
    10201 ggtgttttgc atttcgtaat attcagcgtg tcttaaatct tctacacaca atgtttcatt
    10261 tttattttta ggcataaggc ttcactcctt tgcttgaaat tgagtgagct tttttatctt
    10321 actcgtaatc cttattgaaa caacataata cttttctaat atatacacga cttgagggca
    10381 ttcctccatt ctcattacaa gaatttctta ggttcgccct ctgcttttca gcattagttc
    10441 aactgcttat tgttcttcgt cagtttattc tcttgatgag aacccaatac ctttcctcgt
    10501 tccgataatc ttatctatac atatatatcc ttaggtcact agctataagc ctgctggctt
    10561 gataccgcct gtaacgttat atggcatttc ataacctata ttcttacttt gccacaccag
    10621 ctacgatttc tcgtaccttt gcatttctac aaagttcaaa tttagacccg tacattcgct
    10681 gtttcgtcag ttccttatag aacattctaa ccatagatat tttatagacc cccgacctgt
    10741 tggatacgct acccgcctct ggatagtttt cgatagaaga tatatgttca tcaactatta
    10801 cggtatcttt cagccgtctt taccaagctt caaacattct gagtttcctc atacaatgct
    10861 tgtcggaggc tcagggcagg cgtttcagag cgttacttca tcattccacc tgtcagatta
    10921 tcagttctcc taataaccaa actttttcgt tcttttatta gtgccttagc ttttcactaa
    10981 ggaacgagtc gcacataaat tttgtccgaa attcatttaa ttgtcctctc tttctttgat
    11041 ttcttccata catctgtcag cttctttgcc gacagttaaa atgcacatca agactacacc
    11101 gatacccatt ccaaatgata ccagcaataa gtctttcaat aattcccaca ttttttcatc
    11161 actcctttac gttggcaacc atttcttcaa ccgtggctgt ctgttgcttg attatctggt
    11221 agtgtcgttc ggtcagtttt gcctgctttt caatcgtttc cagatactcc gtctgattgt
    11281 ccttgtctat ctgcttcaac atcttcaagg tcggtgcaac ctgcctttgt agccagttga
    11341 gtgtacgctc cagcgtgtaa ggttctggct gtgttgtcag ctttacgggc ggtcgcccct
    11401 cgccaatgaa ccaagcccag cgtacattgg ttttccagtc gctttttcgc ttgtctggtt
    11461 ctttatcagc gaagcggata tattgattga taatagaaaa tgctgtcagt tctgcgtcat
    11521 aatgtgtcag cagttccaca acagcataat aggcacgttc atttttcaaa cgtatctcaa
    11581 atctattttt tatggggact tcctcaatcg gtatgccaag tttggcgtac tgttcgtaat
    11641 tcttttcata acagcagaag tacacttcac ttgaaaatga accaatatac agcgtgtgtc
    11701 ccataccgta tttatccgtt tcattatgct ttaccagctc tccagaacca tagcttttga
    11761 aagaacggaa tttagaaata cattcctcat tctcgcattt tcgtatcagc tctggaatat
    11821 caagtaagcc cgttcggtca ttgattgcca aatcaagacg cttcattaca ccgccctcaa
    11881 ccaatgcgtc cgtgaagaag tcataccaac ttcgctcttg tgccagcaga tagctttcaa
    11941 actggcgaca gcctttgcct ttcagttcca gcaggacacc tttttcttcg tcctgcgata
    12001 catacacaaa cacatctccg atatggtaat gctcggtgta tttgtaatgt ccgtaatctt
    12061 cgtgaagcat atagccgatg ttgagcttca atatatcctt gatgatatgc tttatatcca
    12121 ttgtgggaaa acggatacgc acataatcaa acagcaggaa catgggattg ttgggattga
    12181 atttttccac cgcttctaaa agcgtatgtt tcatgtcctc ggtcagcgtt acctttcctg
    12241 cttcgatacg gctcaaatgt tcacggctga tatttgccat gattgcaagc cttgtctgcg
    12301 atacgccgta tgcacagcgt ttttctttca aggcggttaa aaaatcagtt tcattcagtt
    12361 gtcatacccc caatcgtgat aattttgtga tattgtgata atttcaaggc tttatcacaa
    12421 aaggcgaaat gtacgaaaaa cccttatttc atgcggtctt gcaaaggttt ttgtggaagt
    12481 ttccgccgta attgtgcccc tctgttagat aatgaggggc ttgtatctgc tggcgtggct
    12541 aacgccacac cagcaacggc tagtccgtgc cgtcgccttt cgcttcgcac gtcgccgtcc
    12601 cgtcctgcct tgcgtatgca agtgagccta tggtctgcaa aaaatcatgt ccttttggaa
    12661 ctaagggtgt gtaaaattca cttatgacgc ttgttcccac atcacaatag ccacgtccct
    12721 tgatacgctt ctggaaaaac tgttttttca catcagaact gaacagcata ccgtaaccta
    12781 attcgctgat acgccccaag ccaacacgga aattaaaatt atctctgata ccgtccgaga
    12841 aatattttgc gtctggacgc tggcaggcaa caataaggaa atatcctgct tgtcgtccta
    12901 acatgacgat tttctttagc tggctaagta ggctcacact ttcttttgtc cccagcattt
    12961 caaaaaacgc cacatattca tcaaagataa gaaagcaggg cggtaaacca agataggcat
    13021 agttttcgcc cgttttatag tctgggtgtc gcttcatttc ttcgcttctt tgtaccatgc
    13081 cctcataaaa ggcattgaca caatcaatca tttcttcttt ggtgtgatac acatttccca
    13141 ttaccgtacc taaatctgca aggtcagcgt tcttcgggtc taatatgtaa agaacagcgt
    13201 tcgtatgtaa cagagcttca ataagcgtca gcagaaaata cgttttaccg ccaccagtcc
    13261 caccagcaat cagagcgtga gggagtgcgt catattccca tacaagattt ttcatcagcc
    13321 taagacagcc gttttctgct ttcacttcat caatggtaat gcggttcgct atcatatcat
    13381 aaagcatggt gtattcgata taaccgtcat gtaacgtctt gtcggtcagc tcacaataca
    13441 agccactttc caatttatcc tctaaccgta agagctggtc ttgatatttt cctaatgtaa
    13501 tttcacagcg gatatgaagc agtccttttt ccatttgata ataaatcttt ggaaaccaga
    13561 tgattttttc ccttgatctg ctttgcaggt cagtaaaaaa accgctgtct tgtacggtgt
    13621 ctgcttcata ccacttgttt tccagtatca ttcgtgccag cttttgacgg tgcaggagct
    13681 tcttgaaact gtcataacag aagcggtaat acagaaaagc gaccaatgca caaacaccag
    13741 tcgctatcag tagggttatg aagttgtaag tggaaagcgt caaaccgttg tctaataagc
    13801 tgaaatgctc ccaatcggta cgcatgagct gtttcatatt cagtagcagg ataaccgcaa
    13861 tgaatacaaa cagaagcgtc cctatggaaa agtggtagac aaggttcttg tcgctggctc
    13921 tgatacggtg tcctttgttt aaaatcattt tcataaatca atcactcctt tctgggtacg
    13981 aaaaaagcag tcaatcctaa gactaactgc tttgtgtgta tggatatgaa gttgtcaaac
    14041 tgggatttat tgttcttaac ttttctgtcg ttataaagct gacttacgca cattaacctc
    14101 tgcacagacc agcccagcta tatgctccgc tgtttcattt gtcagtacaa agagcattcc
    14161 gtcattacgg cattttttat gtgtgtcgcc attcaaggca taaacaaaac cttttacaca
    14221 ggtatcacta caggcattag ggtcaatcag tctcttgcag tcacgagaag tagtcatttt
    14281 cttttgcata tcagcaggaa gcgaagcgat tatatcctca tactttccag cgttgtctcc
    14341 gtaaatccgt gcaaaaacac ctgtcttgcg aaacacccaa ttcattactg ttttcttctc
    14401 tagttggtat gaagcggtgt aaccgctttt tgcttccttt attacaaggt cacagccctg
    14461 ctcaataagt ttggtattaa gtttctcgac aaacgcttgg tgttctggcg cgattgccga
    14521 tagaaattct ttgaatgaac ctttttcttt tgccattatc tttttcctcc acaaatttca
    14581 atttatccgt ttcttcatac acatattata acagttgctt atatccgcta caatgaaaat
    14641 ctagtttgcc agcttatttc tttggttgcc cctgcggtgc atggttctgt ggattgccta
    14701 cttgaccgcc tttattcttc aagataatat cgtcagcctt gatataccag tccacattga
    14761 cacctcgata gctggcgttt gctaccgtat cggctacggg attgacaagc tctacctctg
    14821 cattatacgg atagtccttg acgggaatat cagcaggaat tgatacttgt atcatacgtt
    14881 cctgcacact acatttcaaa tcataggttc ttcgtgtgat ttcttcactt gttgaaccgt
    14941 cgtcattttc tgctcgcacc tcatgtctga gggcagagaa cttcaataca ccgaaagttt
    15001 tttccttgtc taatacaata ccgtttgcta atctcataat catttacccc cttacttgct
    15061 ttcctcggct ggcaacatat catcagccgt taagatatag tttgtgaacc ctcgtccttt
    15121 gaccgcttta ccgtctgcgg taatctttgg attgataagt tttactcgct gttctggttt
    15181 gaaatgcttt tcgcctgctt tcgctggaat ggttacgata atatcatcag ccctttgtac
    15241 gtcagagtac aagttgtagc ttcttgatac gggcgtaaag cgtccgttaa tgcgttgctg
    15301 ttcaatcttg ttttcgccag caaattccaa gtttccaaaa gtctgtgcca tgttcggcac
    15361 tacatatttt aattccatag tgttttacct cgtttctttc ttctttttta agtttgttga
    15421 ttgtgctttc ttattctggg aattagggaa ataccagtaa tcccccagat agtaaagggt
    15481 aaatcaatgc ttcgcaccct tgactatccg tgtgcttgca ggttgttggc agacaagcca
    15541 gaataagtaa acgtctgccg tttgacagct tcggcagaga gcgtgatttt tcttttctca
    15601 taccgttacc gccttatgat ttcttcattt tacggcgttt gtaaagatat gttccagcca
    15661 gtccaccagc agatgtaagc aacattacca gaaatgccat gacatttgtg ttgtcgcccg
    15721 ttttaggact gtctgttggt ctgctcggtt tttctggtgt tgttggcgtt tcgggtttct
    15781 ctgggacttc tggtttttcc ttaaaagtaa tcgtctgtcc ctcgtcctca atgtccttat
    15841 gctcagtaac ttttttcggc tcgtttggat tgcttaaatc atacaattct tcaaaagtta
    15901 caagctgttt gccgtcaaga gaagtagcgt caaaggtaaa ggtaacttcc actttcatag
    15961 tttcgctgtc agcgataaac gtataatcac tttccacacg ttttccattt ataagaagct
    16021 ctgcattttc ttctttcaac atctgccagc ccacaagttt atactttgta ccaacttcca
    16081 agccctctaa ggttacagta tcaatgattg ttacgtcttt tcctgcttca agctctttgt
    16141 taccgtcctt atcggtagca gttgtatgta ttttgatgat acgttctgta ataagtaccg
    16201 tctgcccgtc gtcctcaata tctttatgct ccgcaacttt catgggttcg tctggattgc
    16261 ttaagtcgta taattcctcg aatgttacca gatttttacc gccaagctcg gacgcattga
    16321 atgtataaga aatttccact ttcatttctt catcatcagc aacaaaggta taatcgcttt
    16381 ctacacgttt cccgtcaatg ataatctcgg cgttttcttc ctttaacatc tgccagcctt
    16441 ttaactgata cttagtgcct tttgtaagtc cgtctaattt gacagtatca acgattgtta
    16501 cctcttttcc tgcaaggatt gtcttttcgc cgtctttact ggttgctgtg gtatggatag
    16561 tgatttcctt ttcgtattca tcagtcaaag tccctaaatc aatcacaaga ttatttcttg
    16621 ataccacgat ttcaaatggt gggataagtt ccatgccttt gttgctgtca gagcgtaatt
    16681 cttcaataat gtaagtatcg taaggcaacg cacctttgct gtcgtctggt tcagaagttc
    16741 caaaccatac accgtcctcg cttgttttgc cagcgttggt attgtgcttg tgcgaagccc
    16801 attttgaaga agtggagaat tgcccattat cgtcagttac cacaacatga ctttcgcccg
    16861 ttgtcttgct tgtgatccta aagggaacat cagcaagacg cttgtgtgtg cctgcaccga
    16921 ttttcacgcc ctcaatatcc ccacgcttaa tctgattgta gatagagtgg gcttcgtctg
    16981 ttaagtccac gatttttccg ttttctgtga ttgtaaaatc aatcggcttc gcaccgtctg
    17041 tcaagtaacc gtttggagct tgtttctcaa cgatacggaa attcccgtaa ggcaaaaggt
    17101 cagcagaagt agaagcgata ccctcaatat ccgtatggat tgtttttaca acttcgtttt
    17161 tcttgtatat cttgccctca accaataccg cattatcatt taaggaaatg atgtcaaagg
    17221 cagtatcttt caaagtggca cttccttgtg gtttggtatc tttggtttct aaatctcgtt
    17281 tctgaatttt gacaccgcca cgaatgactt tatctgatac ggaaaactgg ttacttccag
    17341 ttaatacggc aaggtcgccg tcctcggtaa tctgcgtaag gtataaggct tttatctgtt
    17401 cttcactacc attcgcctgc atatatgcac cgtctagtaa gtagcccgtt ggcgatttcg
    17461 tttcttcgac cgttagtgta ccaagaggta aaaacgcttt tccgtcctgc atatagaagc
    17521 tatcgccaga taccttgtat gcgtctgcta attttgtgat gtaatgggtt gtcccgttac
    17581 tgtctgtttc agcggttgtc tttgtaaccc atgtacgagt agcttcggca ggaagattgt
    17641 ctttattgta gaagcctgca taatatttcc atgtaaactc cgccccctct aaagaagcgt
    17701 tcccttgtgg gttggctttc tgtgtttcca tgtcaatttt aaaaagctca atcaaagtat
    17761 cggtaacttt tggcgtatca gatactttca aagtcgctgt ctttccagct tcgactttta
    17821 aggaatacac cgtagtatca actttatacc ccaatggtgc agataattct ttgatatata
    17881 cggtagtagc tttgacttct gcaacctctg tatttccgct gtcgtcagtc gtaagggtag
    17941 caatctgttt ggtgcaatcc ttatcggaaa agacaccgta agtcgcacca gcgatagagt
    18001 aatttccgtt accgttagta atgctggtat tattggaagt cttttgaagt ttggcatttc
    18061 cgacatttaa cttcgcccag aattgcccta attcctgccc ctcgccagag tagatataac
    18121 cgccgcattc atagcgtcct ttgttttctt tcacaaaggc ttttgcacca gcaaacactt
    18181 catcttgtgt tgcctttggt atttcatcat aagaagctcg cacgttatca cattgccagc
    18241 ctaagtgaac actcaatctt tgccacacaa caagctgtct taaaaggtag gcgtgatttt
    18301 tgcttatccc attgtggttg tcggtgtatt gcttcacata ttcgatagat aaggcaacat
    18361 cacttatctg gtcggcactc atacgggagc ttgcgtcagc tctggtcttg tagccgttct
    18421 taaaatctgt gttaatatcg atacaataag cgtcctcgcc ctcaacggtc aaatgcccct
    18481 cgttaaaggt agaaccaatc gaaccgtcat tcattacttt ttcaacgata ccgacacgtt
    18541 cttcactttc cgtccagtat tgcttgcttt ctgcatggac aagtgtagtc ggtaaagcag
    18601 taacgacagt cgcaaaggca agtacgcccg tacacaatcg tttcaatatc tttttcataa
    18661 ttctaaatgc tcctttcatt ttgggtaata aaatagccgt ccataatgaa cggctggaaa
    18721 tagaaaagga acgtcaattt aggcgttcca tagtctatga aatattcaat ttttttcttg
    18781 cttcaatact gatgtgccgt accatatctt tgcatatcta ggaaaacttg cgtatcaagg
    18841 ctcattcatt ggtagtaaat tagtagtaaa ttgatgtgtt tgtttccttg aaaatgctga
    18901 tagatactat gttttagcgg ataatcaact ttttagtatg ttttttgcat aaaaattgag
    18961 tagatagtag ttttattgta cttaatgatt gtatttaagt gattagattt gaaattgaat
    19021 aatgtagata ataaaaaaat attaacagaa cttaataaac tccattaata tttttttatt
    19081 atttttgaaa ctgtgataat tatcacggaa gcatagaaaa taaagtgtta agatttaaac
    19141 aagatagtaa gtaagtaaaa ctaaaatata agaaaggtga taaaaatgaa actaaaatta
    19201 gattcatcta agttcaatga aggtctgaat tatctaaaaa aagactacaa gatatttgca
    19261 ccagttttaa taccatttaa aggtactttt tcagatactg atgttataag atacaaggag
    19321 gtaaacgctt ttgaagaaat ggaatttgct aagaaagcaa acttttcacc aaaagatgtt
    19381 gtacttccca taaatcaagt attgttttat tttactgaaa aagagtttaa ggaaagcgat
    19441 ttagacaaca agaaaatttt aattttctta agagcttgtg acataaatgg tataaaaaga
    19501 cttgatgaaa tatatctaaa taatggtgaa gaaaaagatt atttttataa aaatatcaga
    19561 gataaagtaa agtttgcact tgtagggtgt aaggaaagtt ttagaaactg tttttgtgtg
    19621 agcatggatt ctaacaaaac tgataattat tcaattggat taaatataga aggagataca
    19681 ctgtacttag atataaagga tagtgaattt gaagtattta atggagaagc aactgaattt
    19741 aatgttgatt atgtaactga taatttaata tctgtagatg tgccagagaa tattgattca
    19801 aatgaaatga taggaaattc aatatgggat gaatatgata caagatgtat aggatgtggt
    19861 agatgtaatt ttgtatgtcc aacatgttca tgttttacaa tgcaggatat tttctataag
    19921 gaaaacgaaa atgtaggtga gagaagaagg gtttgggctt cttgtcaagt agatggatat
    19981 acagatatag caggtggaaa ttcttttaga aaaaaacaag gcgaaagaat gagatttaaa
    20041 actatgcata aaatacatga ttttaaaaaa agattcggat atcatatgtg tgttggctgt
    20101 ggaagatgtg atgatgcctg tccgcaatac atatcatttt caaagtgtat agaaaaaata
    20161 aatgatttag taattagtaa ggaggaagta taaatgaacc catatatacc agtaagtgca
    20221 aaaatactag atatagttaa acatactgat aaagaatgga cttttagagt aaactgcaat
    20281 acaaaaggtg tattgcctgg aaagttttat gagatatcta tacctaaata cggtgaaagt
    20341 ccaatatcag tatcaggata tggagaggat tatattgact ttacaataag aaatgtagga
    20401 aaagtaacta gcgagttgtt taattataaa gaaggagatt ctttttttat aagaggtcct
    20461 tatggaaatg gatttgatgt atccctttat gaaggaagag aaattgtagt agtggcagga
    20521 ggaagtgcat tagcccctgt aagaggaata gttgaatatt tttataataa taaagaaaaa
    20581 tgcgaaaagt ttaaattaat agtaggattt aaatcaccaa aagatatttt atttgcagat
    20641 gatttaaaga gatggagtaa aaaacttgat attttagtta ctgtagatgg agcagaggaa
    20701 ggatatagtg gtaatgtagg attagtaaca aaatacatac cagaattgga tatgaaagat
    20761 ataaacaata cttctatagt tgtagttgga cctccaatga tgatgaaatt tacagtagaa
    20821 gaatttttaa aaagagattt agatgaaaag aacatttggg tttcttatga aagaaaaatg
    20881 tgttgtggaa taggtaaatg tggacattgt aaaatggatg atacttacat atgtttagat
    20941 ggaccagtat ttgattattc atatgctaaa aatcttattg attagggggt gaagtttgtg
    21001 ataagagatt taaataccaa aaaagtaatg aaaaatgctt atagaattac aaaaacaaaa
    21061 tatgagactt ctttaagagt tagagtacct ggaggtctta ttgaccctga gagtttagct
    21121 gtagtttcta aaattgcaag tgagtacggc aatggacagg tgcacataac tacaagacag
    21181 gggtttgaaa tattaggaat aaatatggaa gatatggaag aaataaataa aattatacaa
    21241 cctgttattg aaaaaatgaa tataaatcaa agtgagaaaa acgcgggtta tccagcagca
    21301 ggtacaagaa atatagcagc ttgtatagga aataaagtct gtccaaaggc tcaatataat
    21361 acaactgaat ttgctaaaag aatagaaaaa gctatatttc caaatgattt acattttaaa
    21421 gtggctttaa ctggttgtcc aaatgattgt ataaaagcta gaatgaatga ctttggaatt
    21481 attggtatgg ctttaccaat atatgaaaag gatagatgtg taaattgtgg agcatgtgta
    21541 aaaaaatgtt ctaagatatc tgttggagca ttaaaaacag aaaataataa ggtggtaaga
    21601 gataaagata agtgtatagg ctgtggagag tgtgtactaa attgcccaac aaatgcatgg
    21661 actagagatg agaaaaaata ctatagatta gctataatgg gtagaacagg aaagaaaaac
    21721 cctagactag cagaagattt tcttttatgg gtagatgagg acagcataat aaagataata
    21781 cttaatactt atagatatgt agaaaagtat atagataaag atgcaccagg aggaaaagaa
    21841 catataggat atataattga tagaacagga tttatggaat ttaaaaaatg ggcacttgaa
    21901 ggtgtagagc ttccagaaat aactaaaatg tacgaaaaca tatactggag tggaattaaa
    21961 tatctataaa ttgagtaaaa catatatttg aataaattaa aatttaatag aaggaagagg
    22021 gagttatgca taaagaaact ttggataaat taactaatgc agctataaat aagataaatt
    22081 tattaaacac aagtaaagta aaatatttgg tatcttctgc gtttgcagga ctttatgtag
    22141 gtataggtat acttttgata tttactattg gaggactttt gactgatgca ggttcaccta
    22201 tgactaagat agtaatgggg ttatcatttg caatagcact aagtttggtt ataatgacgg
    22261 gaacagagtt atttactgga aacaatatgg ttatgtctgc tggtatgtta aataaaggtg
    22321 taagtataaa agatacttct aaaatatggg catacagttg ggtaggtaat ttaatcggag
    22381 ctttggtttt aggcattata tttgtaggaa ctggtctagt agacaaagga cctgtagctg
    22441 aattttttgc aaatacagca gctagtaaag catccatgcc atttacagct cttttcttta
    22501 gagggatttt atgtaatatt ctagtatgtg tatcagtgtt gtgttcgttt agaactaata
    22561 gtgatactgc aaaaataatt atgatattct tatgtttatt tgcttttata acatcaggtt
    22621 ttgagcatag tgtagcaaat atgacaattt atagtgtttc attattttca ccaacaataa
    22681 gtacagttac tattggagga gctatttata atttagtagc tgtaacactt ggaaatattg
    22741 ttggaggagc tttatttatg ggtcttggaa cttatatatt aggtaaagaa aagcttaatt
    22801 aaatttattg tataaattat aactctcttg ataaatacat ttttagtatt gttgagagag
    22861 ttatttttat atttttgaaa aaatatttga aacaaaaaaa atatgggagc atacgaaaat
    22921 atatcggtta tatatataaa aaatacgttt atatatgaat tatatagttc taaatataaa
    22981 aaaagttaaa gtcctaccgt aaaaaagcgc attttgaata agataacaaa tatgataaaa
    23041 ttggtcttgt tgaaattttt aggggggata tgatgacaaa gaaactagta atatcaaaaa
    23101 caaagttgtt tatttttata atagcattta tttctatatt tatatattta tttggaagta
    23161 aaaatacact tataggtgta ggtatagtaa cagctatgct aacactcttg gaaagagatt
    23221 taactatttc tccaattaaa aatttactga agtatttagc aataaatata atcttaggaa
    23281 tactatcatt ttttgcagta caaaatatgt atttaggagt tttattaaat tttatagcat
    23341 tatttataat agggtatgta tttagttatg acttaaaaag agcagtatat gtaccctttg
    23401 gtctaatgta tatatttatg gtaagtatac ctgtaggaaa aagtgaattt cctatgagat
    23461 tgtcggcttt agctgttgga gcagttataa taatgattgc tcaatttgtt atgaatagaa
    23521 ataggatgaa aaatgtcgga gataaagaac tgatatctat atgtgatgaa ttattagaaa
    23581 aaattagcct tttaaaaaat actattaatg atgatagttc tataattaaa tctagtatga
    23641 gaaaaataga tagctgtaat tatagaataa attctatatc taaaaatttg aaaatggtta
    23701 tttttgataa tagaaaagat gacttttata tcagtattag aggtatagac ataatgaata
    23761 ttttattttc attagaaaga ataagtttaa tcctggaaag atacaaaaag gatagtaaag
    23821 aatttgaaga tgaagatata aaaaatattt tagaagaaag tagcataaat agtaaatcag
    23881 atgttttagt tgtagcaacg aaagaaataa actatattaa gatgtgttta gaaaataaag
    23941 ataccataac tgataaagag atattaggat ttagagatta tgttattgct caggatacta
    24001 aaaatataaa tttaaaagaa atttatagtg ttttagaaaa tttatatgag tttttagtag
    24061 attataaaaa agtaaaatca agagacgaaa agaaagctga aagaaaatca aagatacctc
    24121 atgaatttaa acgactatca atatataaga aaaactttaa tttaaattct ataagatttt
    24181 cttatgcagt aaagattgct ttagctacag ctgtagcggg ttttattatg gattatttcc
    24241 atttaagaga tggaagatgg ataatgttaa ctgtcttttc attaacacaa ccttacgcag
    24301 aaaattgtat acaaaggtct agaaaaagaa tagaaggtac atttatagga gctgtaatat
    24361 ttattgtatt attttcaata ataaaagata gtacattaag gtcgttaata gttcttttag
    24421 cagggtatat aaactcttat gtagttgatt atagaaaatt aatggtatgt gtaactgttt
    24481 cagctcttgg ttcagcagta gttatgggag acccaaatgt tttaacaata agcaggattt
    24541 catatgtagc attaggagca attattgcat taatagtaaa taagtttata ttaccatatg
    24601 atgctaaaac aggctatcaa catgttatag aaatgtataa aggaatagtt aaaaatataa
    24661 ttgatgaagt caataagtct atagaaaatg tagctgatgt ttactatata aaaaatttat
    24721 tattgatacc atcacttatt gaagatagac ttatgttgat aaatgctata tataaagata
    24781 aacatcaaga ggatttttta gaaaatcaga aattactaat aagtaatatg tataatctat
    24841 atataaatgt taataaaaat aaaataaaag atgaagatgt tgaaaaaata ttgagagata
    24901 ccaattatat ttcaaattac aatgtagata agtatgatga aggaagaagt gtaattttag
    24961 agagtattgt aaatactaaa agtctaggtg acaagataat atgtctaaac ttactgcaaa
    25021 ctctaaatgg tgtcaaagaa atgtatagaa taagtaatat aactaaagtt tcaataaaag
    25081 aagcagctta gatattaaat tatagaatag ccatatattt aaaataaagt atatggctat
    25141 ttgttttata aaatactaaa agaaaataat atataaaaaa caaaaaacat atatttatga
    25201 attttatatg aaaatagtta aaatattgat ttttttcatt ggttgaaaaa acaatttact
    25261 taggataaac tataatagta ttcaaatatt atgggggtta gatttatgag taaagatgta
    25321 aaggtaaagc gtaataagaa atatgataca tttagtataa ctatggaact tgagagacct
    25381 ttactttatg atgaggttga gaacaaagat gataaaaata ataatagaaa atttaacata
    25441 aagaataaga tatttaaggg aataggtata ctatttgtat tgattttgct tggctttttc
    25501 atatggataa ataaaacata tgaacctcaa aagctggcaa aagaagctct agtcagcaat
    25561 agtaaagttg aagtaactgt aaatgaaaac atttcattta caccaaaagg aagaaaagtt
    25621 tctaaaggtt taattttgta tccaggagct aaagtagaaa tagaatctta tgctccactt
    25681 gcaagaaaaa tagcagaaag tggatatgag gttgtaatcg taaagatgcc acttaatcta
    25741 gctatacttg gaactaataa ggcacagaaa gttatggatt cttacaacaa catagaacat
    25801 tgggtaatag gaggtcattc attaggagga gttgcagcat caaattttgc acgtgataat
    25861 aaattaattg aaggcgttgt atttttagct tcttatccaa tgggtgatga gttgaaagaa
    25921 ttaggaaaaa aagttatatc tatatggggg agcaaagatg gagtagtcaa ttttaaaagt
    25981 cttgtagaat caaaacaaaa acttcctgat gatacaactt atgttgagat tgaaggagga
    26041 aatcatgcac aatttggaga ttatggaaaa caaaagggag ataatgatgc tattataagt
    26101 caagaaaaac aacttaatat tactgccaat agtatcatta aatttttaaa gaatatatct
    26161 taaactaaaa tttaaaaaat ataattttat aagttattat ttaaagtaaa tattaataat
    26221 ataatagaat gaatatttta ttacaagggg gattttaata tggaatacga tatgccactt
    26281 tacagaccac caagtgaggc ttatagtctt ataatacaag tcacactagg atgttctcat
    26341 aacaaatgta cgttttgtag tatgtacaaa tctaaaaaat ttaaaataaa gccactagaa
    26401 gtaataaaaa atgaaattga tatatttaga agatattata agcatgtaga aagaatattc
    26461 ttagcagatg gagatgcatt gataatacca atggagaaat taagagatat tatcttatat
    26521 ataaaagaag tttttccaga gtgtgaaaga attactatgt acggctctcc taaatctata
    26581 gagaaaaaat ctgatgatga acttaaagaa ttaagaaaac ttggtgttaa aatgatttat
    26641 ctagggcttg aaagtggaag caatgaagta ttagaagata ttaagaaagg ttttagtagt
    26701 gaacaattaa taaaagttgg tagaaaagtt aaaaaaagtg ggattaaatt atcagccact
    26761 gtaatagcag gtcttggagg aactaaaaaa acacatcagc atgcagttga tacaggaaaa
    26821 atgttaggag caatttcacc agattatgtg ggtgtactta gtttaatggt agaacctaat
    26881 actgaacttt acgatttact taaggcagga gagtttacaa tactagagga taaggctgtg
    26941 ttacaagaaa ttaaagagat gataaagaat atagatgcta atgaaaaaat tgtatttaga
    27001 agtaatcatg catcaaatta tgctaattta aaaggtgtat tacctgatga taaacaacgt
    27061 ctaattgatg aaattgatta ctatctaagt aaccaaaagc taaaaagaga agaatataga
    27121 agactatagt ttttgatata tcaatctata ttgataggta aatactaaga ttatttagat
    27181 acaaaaaatc atgctacatt aatagttgct tactattgat gtagcatgat ttttttatta
    27241 aaaaacaaaa tggtatattc atatataata tatcaataat aatgaaaatg tgaactagtt
    27301 taatagaatt ttacctatta taataaaaac aggaatttaa ataataaaaa gtaaag
//
LOCUS       DAJMZY010000049        26704 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.049, whole genome shotgun sequence.
ACCESSION   DAJMZY010000049 DAJMZY010000000
VERSION     DAJMZY010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 26704)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26704)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26704
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.049"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            complement(216..1466)
                     /locus_tag="OE968_002028"
     CDS             complement(216..1466)
                     /locus_tag="OE968_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1015 domain-containing protein"
                     /protein_id="HCP7219307.1"
                     /translation="MATIKPFKAIRPNKYIVDKVAALPYDVMNSKEARRIAEGNPYSF
                     LHIDKSEIDLDENIDLYDEKVYLKARENLDEFRKQEILVKDDKECIYIYKQIMDGRAQ
                     VGIVACISVDESLNGTIKKHEYTRPEKEIDRTKHIKYCDANTGTILVTYKHQRVIDDI
                     INDFMDNNEPLYDFITDDKIEHTVWKIDNDDIIDNLVDKFEKLDYLYIADGHHRTASA
                     ENVAKEMRAKNPNYTGKEEFNYFIAMIAPDENLMVLDYNRVIKDLNGLSEEEFINKIK
                     ENFELEEIEGKEKYKPDKKGTFGMYLGDKWYKMKANKNLLEIEDPVDSLDISILQDYV
                     IDAILGIDNPRVDKRIDFIGGIRGLEELEKRVNEDMKVAFAMYPTSIEDLIRVADANK
                     IMPAKSTWFEPKVRCGLFLHEINE"
     gene            complement(1499..2440)
                     /locus_tag="OE968_002029"
     CDS             complement(1499..2440)
                     /locus_tag="OE968_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-3-phosphoglycerate dehydrogenase"
                     /protein_id="HCP7219308.1"
                     /translation="MYNILVTDGIEKEAARKLRELDFNVIEQFYEKDVLGDKLKDVDV
                     LVVRSATKVTKDVIDKALEGKKLKLIVRGGVGLDNIDVKYAQANGIKVMNTPNASSIS
                     VAELTIGQLFVLARFINTANVTMRDGKWEKKKYKGTEINGKTLGLIGFGRIAKEVAKR
                     AELLGMNVIYTDIMGEAQGFNNYKFCDMEEVLENADFLSLHIPFDKNKGAVITEKEIN
                     KMKKGAYLINCARGGLVDEKDLLKALDEGKLSAAAIDVYEQEPTLNLDLVNHPRVSPT
                     PHIGASTVEAQERIGDEIVNVIQDFFLDFNNLIGVAL"
     gene            complement(2680..3756)
                     /locus_tag="OE968_002030"
     CDS             complement(2680..3756)
                     /locus_tag="OE968_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--glyoxylate aminotransferase family
                     protein"
                     /protein_id="HCP7219309.1"
                     /translation="MSKKLFIPGPIDVKEEVLQKMATPMIGHRGKDASMLQKSISEKM
                     QKLFYTNNTILLSTSSGTGLMEGSIRSCTSKKAAVFSCGSFGDRWYKMAVANNVPADI
                     FKVELGEATTPEMVDKVLSTGEYDLITVTHNETSTGIRNPIEEIGEVVKKYEDVIYCV
                     DTVSSAGGIKVEVDKIGIDICITSVQKALGLPPGMSICTFSQKAIDRAKQVPFRGVYL
                     DLLAMYEYLIKKNYQYPSTPSLSHMFALDFQLDNILDEGLDNRFNRHEDMANLVRNWA
                     KKHFQIFTNENHLSNTLTVIENTQGISVSNLNSKLQERGFQIANGYGDLKEKTFRISH
                     MGDYTVEDVQELLDNIDDILGFNK"
     gene            complement(4129..4644)
                     /locus_tag="OE968_002031"
     CDS             complement(4129..4644)
                     /locus_tag="OE968_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HCP7219310.1"
                     /translation="MDFLAKYKVLKKQNSSKSCLVCGTQNELGLKADFYELENGELVS
                     ICNTKDWHQSYPGRVHGGMSAAILDETIGRAVSINDDQIWGVTVSLELKYKKPVPTDA
                     TIKVVGRITKENRKLFEGTGEIILPNGDIAVTATGKYMKMPIGQIAEGDFSNEEWFFE
                     ESKEKVEYIEL"
     gene            complement(5007..6077)
                     /gene="leuB"
                     /locus_tag="OE968_002032"
     CDS             complement(5007..6077)
                     /gene="leuB"
                     /locus_tag="OE968_002032"
                     /EC_number="1.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="HCP7219311.1"
                     /translation="MNCNIAVIKGDGVGPEIIDEGIKVLNKICCKFNHRFDCEYVLAG
                     GCAIDETGEPLPNKTVETCRKNEAVLLGSVGGPKWDKCKGDKRPESGLLKLRESLGLF
                     ANLRPATMYESIKEASPLRTDIVEKGIDFVVVRELTGGIYFGERGRKIIDGIENAYDV
                     EIYNENEIRRIGKRAFEIARNRNKKLISVDKANVLESSRLWRSIMEDLAKEFEDVELS
                     HMYVDNAAMQVVKDPSQFDVIVTNNIFGDIISDEASMITGSIGMLPSASLREDSFGMY
                     EPIHGSAPDIAGKDIVNPIATILSVSMMLRHSFNLEEEAKCIEDAVQSVLNKGYRTID
                     IYNGVGNVVGTREMGELIVNEI"
     gene            complement(6084..6575)
                     /gene="leuD"
                     /locus_tag="OE968_002033"
     CDS             complement(6084..6575)
                     /gene="leuD"
                     /locus_tag="OE968_002033"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HCP7219312.1"
                     /translation="MIANGSVFKFGDNIDTDVIIPARYLNIADYKELATHCMEDIDDK
                     FISKVKKGDIIVATKNFGCGSSREHAPIVIKESGVSCVIASTFARIFFRNSINIGLPI
                     LECEEAANNIDEGDNIEVDFSTGVIKNITKGKEYKAEPFPEFMQNIILNEGLINSIKA
                     NRG"
     gene            complement(6590..7867)
                     /gene="leuC"
                     /locus_tag="OE968_002034"
     CDS             complement(6590..7867)
                     /gene="leuC"
                     /locus_tag="OE968_002034"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase large subunit"
                     /protein_id="HCP7219313.1"
                     /translation="MGMTMTQKILAKHAKLNEVKKGQLIEADLDVVLGNDITSPVAIR
                     EFEKLGIEDVYDKTKVVMVLDHFTPNKDIKSAEQCKFTRSFAKSKGVVNFFDVGDMGI
                     EHVLLPEKGIVTAGDVIIGADSHTCTYGALGAFSTGVGSTDMGAGMATGKCWFKVPGA
                     IKFVLKNKPNKWISGKDIILHIIGEIGVDGALYKSMEFCGDGVEYLSMDDRFTICNMA
                     IEAGAKNGIFPVDDKTMEYINSHKCSTMTKDVNIYEADEDAVYDEVYEIDLAELKETV
                     AFPHLPENTRTVDEIDKDIKIDQVVIGSCTNGRISDLEVVAEIMKGKKVADGVRVMIF
                     PGTQKVYLEAIEKGYITTFIEAGAAVSTPTCGPCLGGHMGILAAGEKSISTTNRNFVG
                     RMGHVDSEVYLASPAVAAASAITGKISKPSEII"
     gene            complement(7824..9566)
                     /gene="leuA"
                     /locus_tag="OE968_002035"
     CDS             complement(7824..9566)
                     /gene="leuA"
                     /locus_tag="OE968_002035"
                     /EC_number="2.3.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HCP7219314.1"
                     /translation="MKCGKYKKYDKMQIVNRKWPDNEIFKAPIWCSVDLRDGNQSLPT
                     PMSVNEKVRMFKMLIDTGFKEIEVGFPSASNTEYTFLRKLIDENMIPDDVTIQVLTQS
                     RAHLIEKTFESIRGCKKAIIHLYNSTSVLQRDVVFNMSKQEIIDIAVEGAKLFNEEVK
                     KYPETEFTFEYSPESFTGTEMDYALEICEAVIDVWKPTPQKKVIINLPSTVEMATPNV
                     YADQIEWFCKNISCRDSIILSLHTHNDRGTCTAASELGLLAGADRLEGTLFGNGERTG
                     NMDIVNVGLNLYTQGIDPELDFSNIDKIIGIYEDCTKLMVHDRHPYAGNLVHCAFSGS
                     HQDAIRKGMIAMKNRDNDYWEVPYLPIDPHDIGREYKEIIRINSQSGKGGAVYIMETD
                     YGFMIPKNMHSDFGNVVKMESDRIGEELSSEAIFNLFKKEYIEVESPYKVKKYKIKSM
                     DELNYENDDSNDTNMIEMTARISYMGNEQRIVGIGNGPVDSFNNALKQCGMKDYKFRY
                     YWEHALEEGSHSRGVAYVGIEHNNEVYFGVSISENINTAAINALMNAINKSYIEEEIK
                     NGDDYDAENISQTC"
     misc_binding    complement(9690..9936)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(10084..10530)
                     /locus_tag="OE968_002036"
     CDS             complement(10084..10530)
                     /locus_tag="OE968_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219315.1"
                     /translation="MSKNKFIYMNYYDNGYFKKGMTIYMVLALIILATIFIYSTTILY
                     ILCIITAVFLFKQGRDFSNKYEGKVYITLDNHSILINNQCIFSIKSKQSQKFNYKIIE
                     KIEVVKNILNIYTNESNYKIRLRALSLEDEKKLLNIIDEKMKKFKA"
     gene            complement(10551..11270)
                     /locus_tag="OE968_002037"
     CDS             complement(10551..11270)
                     /locus_tag="OE968_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase"
                     /protein_id="HCP7219316.1"
                     /translation="MKKSIMDVHCHTLISGHAHSTFKENVEEASKKNIKYLGISDHGP
                     NMPGGPHPFYFYNLHLLPREVQGVKILRGIEGNIMDYNGNLDVQEDMLQHLDYIIASL
                     HRPCIASGTKEENTNAILKVMDKPKVKIIGHPDDSRYPLDYEPIVKKAKDKNILLEIN
                     NSSLSSNSHRTGTWENVSHMLTLCKTYGARVILGTDSHICYSIGEFENAEKVLEAVDF
                     PDELVINYHEDEIIEFFDINF"
     gene            complement(11388..12662)
                     /locus_tag="OE968_002038"
     CDS             complement(11388..12662)
                     /locus_tag="OE968_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HCP7219317.1"
                     /translation="MFIMENDLTMQELLDQQEQVFSKVKVGELTTGKITAVRNDEVQL
                     GLDYGFDGIIPISELNIEKNQYIEDIYHIGDEITAVITKVSQKDGTITLSKLQLDKRN
                     DFAELQKAYDEHRIITVNVEKNIDKGVFANYNTYTFFIPISQLDTKFITDTSKFVGLN
                     LEVYIKELDVRKNRLVASHRDVLQERINKEREERRAQIKAEKEAERARIKQEREEEKA
                     RIKAAKEDLFNSLEVGQKRDGKVTKIMPYGAFVDIGGIEGLAHINNLAWTRVESVEDV
                     VSEGQEVEVYVLDVNKETKKIALALKDINNDPWDLIAKEVQIDDVVNAKVLRIIEKGA
                     FVQIKEGVDAYLPISELSDTRVAKVTNVVNIGDEVKVKILDFKPKTKRMLVSIKEATR
                     EPEEDITEYLEVEESLGSIGELFKDKFKDLEV"
     gene            complement(12862..14229)
                     /locus_tag="OE968_002039"
     CDS             complement(12862..14229)
                     /locus_tag="OE968_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HCP7219318.1"
                     /translation="MENSNTNLGSESVGKLLFKLATPAIIAQIVNVLYNIVDRIFIGR
                     MENGEVAMAGVGVAFPIIIIITACSYLIGMGGGPLAAIKMGEQNNDEAEKIMSNSFSV
                     LVILAILLTIGFKIGKEPLLWMFGASESTIGYSMDYLNIYLIGTVFVQISMGMNTFIN
                     TQGFATTGMMTVAIGALINIILDPIFIFGFNMGVKGAALATIIAQGVSAIWVLMFLFG
                     KKSILKIKKKYMIPKASIILPVLGLGISPFIMQSTESLVLIALNSKLQMYGGDLAVGS
                     MAIMSSIMQILMLPNMGVTQGAQPIISYNYGSGQLDRVKKTFKLCLLSCFTYSTILWL
                     LLMIFPAFFVSIFNKNPQLLSMTSWSIKIYFAGAFMFGIQIACQQTFLALGKATISLV
                     LALLRKIVLLIPLIFILPTFFNEKLFAVILAEPVADITAATITAISFFIFYKCFLSKP
                     KAIKE"
     gene            complement(14479..14943)
                     /locus_tag="OE968_002040"
     CDS             complement(14479..14943)
                     /locus_tag="OE968_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small multi-drug export protein"
                     /protein_id="HCP7219319.1"
                     /translation="MSLRIGGNSLGYLHILILSMVPVTELRGAIPIGIAMGLNPIWVY
                     VFSVIGSTLVSIPLILTFRHVLQFLRGKKLFKGIADVIDRKINSRMKKLKSVSIIGII
                     LFVGIPLPTTGTWTASAIASILKMRIKDAFMGVFLGNLLSGVIVSALSLHII"
     gene            complement(14948..15577)
                     /locus_tag="OE968_002041"
     CDS             complement(14948..15577)
                     /locus_tag="OE968_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family hydrolase"
                     /protein_id="HCP7219320.1"
                     /translation="MKKSVLLLDVDYTVINTDSMIDFFIYSLKNKTFKTIIKLPYIIF
                     ILFMYLIRIIPLKKAKEAIFYPIVDFSEEDLKKFFDDCIMKKINESMKKVIYKNKEED
                     NVIIMITASPYAYMKYFKYYGLADEVIGTEFFYENSRYKNKFIGENCKGIEKVKRIKA
                     VLGKLGIEIDYENSYAYSDSKSDLPMLSLTKNAFLVSKKDGEVIEQINS"
     gene            complement(15611..16498)
                     /locus_tag="OE968_002042"
     CDS             complement(15611..16498)
                     /locus_tag="OE968_002042"
                     /EC_number="2.4.2.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decaprenyl-phosphate phosphoribosyltransferase"
                     /protein_id="HCP7219321.1"
                     /translation="MKQTNTSIRLLTKISDYIKLMRIKQYIKNFFVFSAIIFSNNILN
                     INLFLNTFIAFVCFCLMSSSVYALNDAIDMDKDKKHPKKCNRPVASGRISKKSANILF
                     VVLALISVCLSTVVSFNLSIILSLYLINNILYSLKLKNIILLDVFSISLGFILRVYAG
                     CVAISVSLSNWIILCTFFLSLYLALGKRKKEIETLRDDAVEHRKILEDYDIENLNQMM
                     IVILSSTIVCYALYSTSNPEKPHMIFTTIFVVYGVLRYNYIINTTNENNPTDIVLKDN
                     ALKINVILWIITCLIILIF"
     gene            complement(16527..17765)
                     /locus_tag="OE968_002043"
     CDS             complement(16527..17765)
                     /locus_tag="OE968_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219322.1"
                     /translation="MDGDILMSKILKYKNEMFLFILVVITYLIITKIFFSKTTIFYDL
                     NNTYDVLLDTDTGVLFNLNVFAISQDNSKHILFSAIISIFAYPIYLFCTSIANPGTTD
                     FNSAYGFGLICLQIITSAMSITLVFNHIKKIKMQRLTLILLTMIMIFSFPQLFMTLNV
                     ERFIYSQFSLIFFIVIANKMKGKNSYLVELAAIPLFGITISNIYLYFFNMIFEFKLKI
                     GKMLKHLITFILMAYICVVSTKSYESFMNLGNVIQYDTKFISGEPILEKIAMIIERLL
                     YSVFYFPGASIKKGLFLQNGEVATIPVILTLLALCFCVLSVIENSEKRVPKLCMGIII
                     FNLTLHGIVGYNLVNSSIMAINFSFAVIILLAYFTKALRKNEKNMYNIFLSLLLVTIV
                     ISNVNGFIEILNIGIKSYPV"
     gene            complement(18149..19291)
                     /locus_tag="OE968_002044"
     CDS             complement(18149..19291)
                     /locus_tag="OE968_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HCP7219323.1"
                     /translation="MRYVEYGKTGKMVSVVGYGGLRFDLEKSNQENADLVKYAYEKGI
                     NYFDTAPGYCDDRSEDIFGLAFRQMIKEGKTDFYVSTKEKPKACDTSEKAIEAVKKSI
                     ERLGVSKINFYHVWNIRKMEHYELAMRPGGQYEGLLKCKEEGLIDHIVFSSHQPGDEV
                     IDILSENKFEGVTMGINILNFPYRLKGAKYAVDNGYGVVAMNPLSGGTIPKYNKELSF
                     LSKDGESTIESALRFNIGISQISISLIGFNKKQDIDDACKIADENRIYSDEDIHDIET
                     RLNKNMNEICTGCGYCKVCPKGINTPAYMLFYNEKQMFKKSDEEMTKLVYGLGHWNYT
                     MNSKAKAKECISCGKCEVECTQHLPIIDRLKEIKKWEEDGANSVKV"
     gene            complement(19432..20298)
                     /locus_tag="OE968_002045"
     CDS             complement(19432..20298)
                     /locus_tag="OE968_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HCP7219324.1"
                     /translation="MDNYKKVKQVLWIILFANFAVALLKIIIGNQIKSYSMTADGFHS
                     LSDGASNIVGLIGIFFASKPKDKNHPYGHKKFEIITSLFISGMLFVIAIKIILSAVLR
                     IANPVVPAITIESLIALIITLFINIFVCMYEYRIGTKLNSYVLISDSLHTRSDIFVSL
                     GVLVTLVGVKLGFPVIIESIVPIIISAFIIYSAYGIFRPSIGILVDRVAVDEDYIKEI
                     VFEFNEVRDVHNIRSRGSKSSIYIDMHVMVDPFISVEQSHDLTHKIEKQIQEEINENA
                     QVIVHIEPFYSF"
     gene            complement(20632..22179)
                     /locus_tag="OE968_002046"
     CDS             complement(20632..22179)
                     /locus_tag="OE968_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HCP7219325.1"
                     /translation="MANFFNFILLQKDKIIELLIQHMSLTVTSILIAIIVGVPLGIII
                     SRISSLRKFVLGFVNLVQAVPSMALLGLLVPILGIGSKPAIFMVVVYSLLPIVKNTYI
                     GITSIDPVVLESAKGIGLTRNQTLFKIQFPLALPIIMGGVRISAVTAVGLMTLAAFIG
                     AGGLGYLVFSGVQTVNNNMILAGAIPSCIIALLVDYLFSKIEVAVTPKGLNPKAPKKN
                     YIALKVISVVLVVSMLFVVFSSSFSSKKDTITIGSKDYTEQLILGNVYAELVEKNTNL
                     KVKKNLNLGGSSVAFNAIKSGELDMYVDYTGTLLVNVMKHAPIKDADEAYNVVKDTME
                     KENQLTLLDPLGFNNTYTLAMMPETAEKYGINTISDLTKYGKEFTFSPTLEFENREDG
                     LVGLSRDYGLKFKDVKAMNGSLRYTALDNNESQVIDAFLTDGLIKKFNLKILEDDKNF
                     FVPYYAAPLVREDTLKKYPELEKVMNMLSGKINEETMRELNYQVDELGKSPEEVAHSF
                     LVKEGLV"
     gene            complement(22172..23308)
                     /locus_tag="OE968_002047"
     CDS             complement(22172..23308)
                     /locus_tag="OE968_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCP7219326.1"
                     /translation="MIEIRNVTKKIGNNVILDDISLVVETGTLVVLIGSSGCGKTTTL
                     KLINKLIKPTSGEIYINGKPISQENEIELRRKIGYVIQNTGLFPHLTIKENIELIPRL
                     KKEKSVEEIEKRTLQLLEMVGLDSDEFLNKYPSELSGGQQQRIGVARAIATDAEIILM
                     DEPFSALDPITRTSLQEQLFSLQDELKKTIIFVTHDMDEALKIADKICIMKDGRIAQY
                     DTPENILRKPANDFVKDFIGEDRVWDNPEYIKARDIMIKNPIAVNSTRTVTQGIEIMR
                     TSKVDSLLIIDRAKTLKGIVTVKDMKDIDDKSILLADIMSSEPLHVNEGDNLVEILNV
                     MNRNSVGYIPVISDENKLVGLITRSSLLSVLSEQFLEMEVSVLG"
     gene            complement(23571..24668)
                     /gene="dinB"
                     /locus_tag="OE968_002048"
     CDS             complement(23571..24668)
                     /gene="dinB"
                     /locus_tag="OE968_002048"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HCP7219327.1"
                     /translation="MKHYRKIIHIDMDAFYASIEQRDNKKLKGRPVIVGGNPQSRGVV
                     ATCSYEARKFGIHSAMPSAVAYNRCPYAVFVRPRFDVYKSVSEQIRDIFYRYTDLVEP
                     LSLDEAYLDVTKNKKNIDSSIEIAKQIKKDIFREVGLTSSAGVSYNKFLAKIASDLRK
                     PNGLTVITEENAQDFLDKLPVNKFFGVGKVTSNTLKNLGIKTGYDLRCLNLFELENIF
                     KKRGYELYKFARGIDDRPVEPNRVRKSVGAETTLSHNLDIDEEETRNILDELCEEVCH
                     RLKNSEKFGKTLTLKIKYEDFTKITRSLSLEHYIDEYNDIRSGVDNLLRNVDVNGKQI
                     RLLGVTISNLSDKKETYKDITLFEYMDSIQM"
     gene            complement(25058..26563)
                     /locus_tag="OE968_002049"
     CDS             complement(25058..26563)
                     /locus_tag="OE968_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003374392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HCP7219328.1"
                     /translation="MKVGFDHKKYLEEQSKYILERVNNFDKLYLEFGGKLMGDLHAKR
                     VLPGFDENAKIKVLQHMKEKVEVVICVYAGDIERNKIRGDFGITYDMEVLRLIDDLRG
                     YELDVNSVVITRFEGQPATTVFINKLERRGIKVYKHYPTKGYPSDVETIVSDEGYGAN
                     EYIETTKPIVVVTAPGPNSGKLGTCLSQLYHENKRGNVVGYSKFETFPVWNVPVKHPL
                     NIAYEAATVDLKDVNMIDSFHLETYGEMSVNYNRDLELFPVLKKIIEKITGKESIFQS
                     PTDMGVNRVGFGIIDDEVIRKASIEEIIRRYFKTACEYKKGQVDKGAYDRMKMIMEEL
                     NLKPEDRNVVLPARNYSNKLKESADKNDTCPVVALELEDGTILTGKGSDLMNGTAAVV
                     LNAIKHLANISDDMHLISPVILEPIINLKTKTLASRNVSLSCQEVLTALSICAVTNPT
                     AQFAMEKLALLKGCQAHSTTILNRDDEQTFRKLGIDVTCDPEYPSQNLYYS"
BASE COUNT         8676 a         4842 c         2772 g        10414 t
ORIGIN      
        1 taaaacctta taaatataca aatacaatta tatgaatttt catcctcaat tatagcatag
       61 aatatgacta tctatatcct aaaattatcc atttctaaaa aaaaggtaac tattattaag
      121 aatatcaact tatagaattt atattccaca tacgattttc aatcaaaaaa acaagggcta
      181 aaaagtgaat tgtgcacttt ttagcccttt attaattatt catttatttc atgtaagaat
      241 agaccacatc ttactttagg ttcaaaccat gttgacttag ctggcattat cttatttgca
      301 tctgctactc ttattaaatc ttcaatacta gtaggataca ttgcaaatgc tactttcata
      361 tcttcattaa ctcttttttc taattcttca agacctctaa ttccaccgat aaaatcaatt
      421 cttttatcta ctctaggatt atcaattcct aaaatagcat caataacata gtcttgtaat
      481 atagaaatgt ctaatgagtc aacagggtct tctatttcta ataaattttt atttgctttc
      541 attttatacc acttatcacc taggtacatt ccgaaagttc cttttttgtc aggtttatat
      601 ttttcttttc cttctatttc ttctagttca aaattttctt ttattttatt tataaattct
      661 tcctcgctta aaccatttaa gtctttgata accctattat aatccaaaac cattaaattc
      721 tcatctggtg caatcattgc tatgaagtaa ttaaattctt cttttccagt ataatttgga
      781 tttttagctc tcatttcttt ggctacattt tctgctgaag ctgtcctatg atgaccatct
      841 gcaatgtata gataatctaa tttttcaaat ttatctacta ggttatctat tatatcatca
      901 ttatcaatct tccatactgt atgctctatc ttgtcatctg ttatgaaatc atataaaggt
      961 tcattattat ccataaaatc attgattata tcatctatca ccctttgatg tttgtaagtt
     1021 acaagtatag ttcccgtatt agcatcacag tattttatgt gtttagttct atcaatttcc
     1081 ttttctggtc gagtgtactc atgttttttt attgttccat tcaagctttc atcaactgat
     1141 atacatgcta ctataccaac ttgagctcta ccatccatga tttgtttata tatatatata
     1201 cactctttgt catcttttac tagaatttct tgttttcgaa actcatctaa attttctcgc
     1261 gcttttaaat aaactttttc atcatataaa tctatatttt catctaaatc aatttctgat
     1321 ttatctatat gcaaaaatga atatggattc ccttctgcaa ttcttctagc ttctttacta
     1381 ttcataacat cgtaaggaag tgctgctact ttatctacta tatatttatt tggtctaatc
     1441 gccttaaatg gtttaatcgt tgccattact aatttcctcc ctaattatac aaaatatttt
     1501 ataatgctac ccctattaga ttgttgaagt caagaaagaa atcttgaatc acatttacta
     1561 tttcgtctcc tattctttct tgagcttcta ctgtagatgc cccaatatga ggtgtaggag
     1621 aaactcttgg atgatttact aagtctaaat ttaatgtagg ttcttgttca taaacatcta
     1681 tagcagctgc tgataattta ccttcatcta atgcttttag taaatctttt tcatcaacta
     1741 aaccgcctct tgcacagttt attaaataag cccctttctt catcttattt atttcttttt
     1801 cagttattac tgccccctta ttcttatcaa atggtatgtg taaagataag aaatctgcat
     1861 tttctaaaac ttcttccata tcacagaatt tataattgtt aaagccttgc gcctcaccca
     1921 ttatgtcagt atatataaca ttcataccta ataattctgc tctctttgca acttcttttg
     1981 caattcttcc aaaacctata agtccaagtg tctttccatt aatttctgta cctttatact
     2041 ttttcttctc ccattttcca tctctcatag ttacatttgc agtatttatg aatcttgcaa
     2101 gaacaaataa ttgacctatt gtaagctctg caacagatat actgcttgca tttggagtat
     2161 tcataacttt tatgccatta gcttgagcat atttaacatc tatattatcc agacctactc
     2221 cacctcttac tatcaacttc aactttttac cctctaatgc tttatctatt acatctttag
     2281 taactttagt agctgaacgt actacaagta catcaacatc tttaagttta tctcctaaaa
     2341 catctttttc ataaaactgc tctatcacat taaaatctaa ctctctcaat tttctcgctg
     2401 cttctttctc tattccatca gtaactaata tattatacat aacaaactcc tccaattttt
     2461 attcacttaa tttttccaat ttttattttt taaagtattt tcatcaataa aaaactttac
     2521 ttaatttaac tttctgttta tataattttc aaaatatttt tttattaaag tcatatcaaa
     2581 ttttcctatt gtttgttaaa aatttaatat gtaattttta taaaatatta tttattatat
     2641 attctaaatt tatcttaaaa catacatatt tttacaatat tatttattaa aacctaatat
     2701 atcatcaata ttatctaata attcttgtac atcttcgaca gtatagtcac ccatatgtga
     2761 aattctaaaa gttttttctt ttaaatctcc atagccattt gctatttgga atcctcgttc
     2821 ttgtaatttt gaatttaaat ttgatacact aataccttga gtattttcta taacagtaag
     2881 tgtattggat aagtgatttt cattggtaaa aatttggaag tgttttttag cccagtttct
     2941 aactaagttt gccatgtctt catgtctgtt gaatctgtta tctaggcctt catctaatat
     3001 attatctaat tggaaatcta aagcgaacat gtgagaaaga gatggtgttg aagggtattg
     3061 gtagtttttc ttgattaagt attcatacat tgctaacaaa tcaagatata ctcctctaaa
     3121 aggtacttgc ttagctctat cgattgcttt ttgagaaaat gtgcaaatag acattcctgg
     3181 tggtaatccc agtgcttttt gtactgatgt tatacaaata tctattccaa tcttatcaac
     3241 ctcgactttt attccaccgg ctgaacttac agtatctaca cagtagatta catcttcata
     3301 ctttttaaca acttctccaa tttcttctat tggatttctt attccagttg aagtttcatt
     3361 gtgagttaca gttattaaat cgtattctcc ggtagaaagc accttatcaa ccatttctgg
     3421 cgttgttgcc tctcctaatt caactttaaa tatatccgct gggacattat tagccactgc
     3481 cattttgtac catctatcac caaaggatcc acaggaaaat actgctgcct ttttggatgt
     3541 acaggaacga atggagcctt ccattaaacc agttccggat gacgtggata aaagtatcgt
     3601 gttgtttgta tagaatagtt tttgcatctt ttcacttata ctcttttgga gcatagatgc
     3661 atcttttcct ctatgtccta tcattggtgt agccatcttt tgcaagactt cttctttaac
     3721 atcaatagga ccaggaataa ataatttctt actcattata attcccccct ttttagtttg
     3781 taatatggat agcgttttta ctgtccttat ttttaataac tataatatca agctgaatta
     3841 actatgtcaa cataaaattt attttttata tataatttat tttatatatt ttatgaaaac
     3901 attcattttc taccttttca taagtctgaa ttttctgaat tattctctca aaaaaaatat
     3961 actttttatc tatataaatt aattttttta gtatgtaaat ttgacgctat tacgataaat
     4021 ctttttagta taactaattt atttttatct tgtattttta ttgtattttt gaattttatt
     4081 ttttctaaat ataaaattta tgttttaaaa tgtaaaattt ttatttaatc aaagttcaat
     4141 atattccact ttttctttcg attcttcaaa aaaccattct tcattagaaa aatcaccttc
     4201 tgcaatttgt ccaataggca ttttcatata ctttccagtt gctgtcactg ctatatctcc
     4261 atttggtaga attatttctc ctgtaccttc aaataatttt ctgttttctt tagttattct
     4321 tccaacaact tttatagtag catctgttgg tactggtttc ttatatttca actctaaaga
     4381 tactgttact ccccatattt ggtcatcatt tatacttaca gctcttccaa tagtctcatc
     4441 caatattgca gcagacatac ctccatgaac tctcccagga taactttgat gccaatcctt
     4501 tgtattacaa attgatacaa gctctccatt ttcaagttca taaaaatctg ctttaagtcc
     4561 tagctcattt tgtgttccac aaactaaaca agatttacta ctattttgct tcttcaaaac
     4621 tttatacttt gccaaaaaat ccatctccta accgacatta gtagtcgctt aatattaaat
     4681 aattctaaaa tatattatat aatattaata aaatccctgc aaacttctaa taataaaaat
     4741 aggctacttc aatatgataa gtttaattta aagtattatt ttccaaaaaa taactttatc
     4801 aaaatagaaa ctcaaagtag atataaacct ctttttcgtt attaaaatag taaaaatata
     4861 tttgacttaa tataaaaaag agtgtctcat taactaataa agtttatttt gagacacccc
     4921 tcataaaaca aattatacta caatagattt ttactaattc tacaagttat atatttaaat
     4981 tatattattc aaattaaact ataattctaa atttcattta ctattaattc gcccatttcc
     5041 cttgttccta caacatttcc cacaccatta tagatatcaa tagttctata acctttattg
     5101 agtacacttt gtacagcatc ttcaatacac ttagcttctt cttctaagtt aaaactatgt
     5161 cttaacatca tgcttacaga tagaatagtc gcaattggat ttacaatatc ttttccagct
     5221 atatcaggtg cacttccatg tattggttca tacataccaa aactatcttc tctaagtgat
     5281 gctgatggta acatacctat agaacccgta atcatagatg cttcatcaga tattatatct
     5341 ccaaatatat tattagtcac tattacatca aattggctag ggtcttttac aacttgcata
     5401 gcagcattat caacatacat atgtgacagt tctacatctt caaactcttt agctaagtct
     5461 tccattatac ttctccaaag tcttgaactc tcaagcacat ttgccttatc tacacttata
     5521 agttttttat ttctatttct ggctatttca aaagctctct taccaattct tcttatttca
     5581 ttttcgttat atatttctac atcataagca ttttcgatac catcaatgat ttttcttcca
     5641 cgttctccaa aataaatgcc ccctgttaat tcccttacaa caacaaaatc aatgcctttc
     5701 tcaactatat ccgttctaag tggtgaagct tcttttatac tttcatacat tgtagctggt
     5761 cttaaatttg caaataaacc caatgactct cttaatttta aaagaccaga ctctggtctt
     5821 ttatctccct tacatttatc ccactttggt cctccaacag aaccaagcaa tacagcttcg
     5881 ttttttcgac aagtttcaac agttttatta ggtagaggtt ctccagtttc atcaatcgcg
     5941 catcctccag ctaatacata ttcacaatcg aatctatgat taaatttaca acaaatttta
     6001 tttagaacct ttataccttc atctataatt tccggtccaa caccatcacc ttttatgact
     6061 gctatattac aattcatact ccactacccc ctatttgctt ttattgagtt aattaagcct
     6121 tcatttaata taatattttg cataaactca ggaaatggtt ctgctttata ttcttttcct
     6181 tttgttatat tttttatcac acctgtagaa aaatctactt ctatattatc cccttcatct
     6241 atgttattgg cagcttcttc acattcaagt ataggaagcc ctatatttat agagtttcta
     6301 aaaaatattc tagcaaaagt agaagcaatc acacaggata ctccactttc ttttattaca
     6361 attggtgcat gttctcttga tgaaccacaa ccaaagtttt tagttgcaac tataatatct
     6421 ccttttttta ccttagaaat aaatttatca tcaatatcct ccatacaatg cgttgctagt
     6481 tctttataat cagctatatt taaatatcta gctggtatta ttacatctgt atctatattg
     6541 tcaccgaatt taaaaacact tccattggca atcataaatt ttacctccct taaattattt
     6601 ctgatggttt tgatattttt ccagttatag ctgatgctgc tgctacagct gggcttgcaa
     6661 gatacacctc tgaatcaaca tgccccattc ttcctacgaa attcctattt gttgttgaaa
     6721 tggatttttc tcctgctgca agtataccca tatgtccccc tagacatgga ccacaagttg
     6781 gtgtagaaac tgctgctcct gcctctataa aagtggtaat ataccctttt tctatagctt
     6841 caagatatac tttttgagtt ccaggaaata tcataactct aactccatct gctacttttt
     6901 tgcctttcat tatctcagct actacttcaa ggtctgatat tcttccattt gtacaagagc
     6961 ctattacaac ttggtctatc tttatatcct tatctatctc atctactgtt ctagtatttt
     7021 caggaagatg aggaaaggct actgtttctt ttagttcagc taaatctatt tcgtatactt
     7081 catcatagac tgcatcttca tctgcttcat atatatttac atcttttgtc atagttgaac
     7141 acttatgtga atttatatat tccatagtct tatcgtctac tggaaaaatt ccattttttg
     7201 ctcctgcttc tattgccata ttacaaatag taaatctatc atccatagat aagtattcta
     7261 ctccatctcc acaaaattcc attgacttgt aaagtgctcc atcaacacct atctccccta
     7321 ttatatgaag tattatatct ttaccactta tccatttatt tggtttattc ttcaaaacaa
     7381 attttattgc tccaggaacc ttaaaccaac attttcctgt agccatacct gctcccatat
     7441 cagttgaacc tacaccagta gaaaatgctc ctaatgctcc atatgtgcaa gtatgagagt
     7501 cagcacctat aattacatct ccagcagtta ctataccttt ttcaggaaga agaacatgct
     7561 ctattcccat atctcctaca tcaaaaaaat ttacaactcc ttttgatttt gcgaaacttc
     7621 ttgtaaattt acattgttct gcactcttta tatctttatt aggtgtaaag tggtctaaaa
     7681 ccatcactac tttagtctta tcataaacat cttcaattcc taatttttca aattctctaa
     7741 tggctactgg tgatgttata tcattaccta aaactacatc taaatctgct tcgattaatt
     7801 gccctttctt aacttcattt aatttagcat gtttggctaa tattttctgc gtcatagtca
     7861 tccccatttt ttatttcctc ctcaatataa cttttattta ttgcattcat aagtgcatta
     7921 atagctgctg tatttatgtt ttccgatata cttacaccaa aatagacttc attattgtgc
     7981 tctattccta cataagctac ccctcttgaa tgtgaccctt cctctaatgc atgttcccag
     8041 taatatctaa atttataatc tttcatgcca cattgcttta gtgcattatt aaatgaatct
     8101 acaggtccat ttcctatacc aacaatcctt tgttcatttc ccatataact tattcttgca
     8161 gtcatctcaa tcatattagt atcattagaa tcatcatttt catagtttaa ttcatccatt
     8221 gattttattt tatacttctt aactttataa gggctctcaa cttcaatata ttctttctta
     8281 aacaaattaa atattgcttc actactaagt tcttccccaa ttctatcaga ttccattttg
     8341 actacatttc caaaatcaga atgcatattt ttaggtatca taaatccata atctgtttcc
     8401 attatataaa cagctcctcc ttttccagat tggctattta tccttataat ttctttgtat
     8461 tctcttccaa tatcatgagg gtctattggt aaatatggaa cttcccagta atcattatct
     8521 ctgtttttca ttgctatcat gccttttcta atagcatctt gatgtgaacc tgaaaaagca
     8581 caatgtacaa gattacctgc atatggatgt ctatcatgta ccataagttt tgtacagtct
     8641 tcatatatac ctattatctt atctatattg ctaaaatcta gctctgggtc tattccttgt
     8701 gtataaagat taagtcccac atttactata tccatattcc cagttctttc accatttcca
     8761 aatagtgttc cttcaagtct atcggcacca gccaataatc caagttcact tgcagccgta
     8821 caagttcctc tatcattgtg agtatgcaaa cttagtataa tagaatccct acaacttata
     8881 tttttacaaa accattctat ttggtctgca tatacgtttg gtgttgccat ttcaactgtt
     8941 gatggaagat ttattattac ttttttttga ggagttggtt tccaaacatc tatcactgcc
     9001 tcacatattt caagtgcata atccatctct gttcctgtaa aactctctgg tgaatattca
     9061 aaagtaaatt ctgtttctgg atattttttt acttcttcat taaataattt tgctccttca
     9121 actgctatat ctattatttc ttgtttactc atattaaaaa ccacatctct ttgaagaaca
     9181 gatgtagagt tatataaatg tataattgct tttttacatc cccttattga ttcaaatgtt
     9241 ttttctataa gatgagccct agattgtgta agtacttgta tagttacatc atctggaatc
     9301 atattctcat ctattaattt tcttaaaaat gtatactctg tatttgatgc tgatggaaat
     9361 cctacctcta tttctttaaa tcctgtatca ataagcattt tgaacattct gactttttca
     9421 tttacactca taggtgttgg cagtgactga tttccgtctc ttaaatcgac actacaccaa
     9481 attggagcct taaatatttc attatctggc catttacgat ttactatttg cattttatca
     9541 tattttttat actttccaca cttcatgtta tttccccctt tttctgtttt ttgtattcag
     9601 tatacctcat atcgacgcaa tcctgcacaa ttcataagga taaatgtcaa ttttatcatt
     9661 agaataaaaa aaacctcatc tctaataaaa ttagagacga ggttttgctc gcggtaccac
     9721 tctatttagc tttctaaaaa gctcccttag taatagccaa tacaataatt ataatgacta
     9781 tatttcctat aacgtggaat tactccgatt attctaagat ttaaatctta gaaaacagct
     9841 cctagacaag ttcagaacta tcaactacta aatcacacca tcctttagct ctctgaaagt
     9901 ttcattgttc ttactacttc tattcatcac ttttttaatc atttaaattt tctaaatatt
     9961 ttgatttaat agttattata tacacattaa aatgtattgt caacacaaaa aataattatc
    10021 tcaatttttt atttttgata agcaattcta taaaacatgc taactattga aaacagtatg
    10081 atattatgcc ttaaactttt tcatcttttc atctatgata ttcaataatt ttttttcatc
    10141 ttccaaactc aatgccctta atctaatttt ataattagat tcgttagtgt atatatttaa
    10201 tatatttttt actacttcta ttttttctat tatcttataa ttaaactttt gactttgttt
    10261 agattttata ctgaatatac attgattatt tattaatatt gaatgattat cgagagtaat
    10321 atatactttt ccctcatatt tatttgaaaa atcacgacct tgtttaaata gaaaaactgc
    10381 tgttattata cataaaatat ataatattgt cgttgaatat ataaaaattg tagctaaaat
    10441 tataagtgct aaaaccatat atatagtcat tcctttttta aaataaccat tgtcataata
    10501 attcatatag ataaacttat ttttactcaa attttttcac tcccaagatt ctaaaaattt
    10561 atatcaaaaa attctataat ttcatcttca tgataattta tgactaattc atctggaaaa
    10621 tctactgctt ctaaaacttt ttctgcattt tcaaattctc ctatagaata acatatatga
    10681 gagtcagtac caagaattac tcttgcacca tatgttttac acaatgtcaa catatgactt
    10741 acattttccc aagtacccgt tctatgagag tttgaactta atgatgaatt atttatttct
    10801 aaaaggatat ttttatcttt agcttttttt actataggtt cataatctaa aggataccta
    10861 ctgtcatctg gatgtccaat tatttttacc ttaggtttat ccataacttt taaaatagca
    10921 tttgtatttt cttcttttgt accagaagct atacaaggtc tatgcaaact tgcgattata
    10981 taatccaaat gttgcaacat atcttcttga acatctaaat taccattata atccattata
    11041 tttccttcta ttcctctaag aatctttacg ccttgcactt cacgtggaag caaatgcaaa
    11101 ttataaaaat agaatggatg tggtcctcct ggcatattag gtccatggtc tgatattcct
    11161 aagtatttta tattcttctt actcgcctct tcgacatttt ccttgaaagt actatgtgca
    11221 tgtccactta ttagagtgtg acaatgtaca tccataatag actttttcat taaatttcct
    11281 cctaatattt tacataaatt cgtgaaaata gctaaagggc tatttcaaaa ctaaagctgt
    11341 cataatagac agtgtaacgt tttaaaacag ccccattttc aattatttta cacttctaaa
    11401 tctttaaatt tatctttaaa taattctcca atacttccta aagattcctc tacttctagg
    11461 tattctgtta tatcctcttc tggctctcta gttgcttctt ttattgaaac caacattctc
    11521 ttagtctttg gtttaaaatc aagaatctta actttaacct catctccaat attaacaaca
    11581 ttagtaactt tagccactct agtatcactc aattcagata ttggtaaata cgcatctaca
    11641 ccttctttaa tttgaacaaa agcccctttt tctattattc taagaacttt agcattgaca
    11701 acatcatcaa tttgtacttc ttttgctatt aaatcccaag ggtcattatt tatgtctttt
    11761 aatgccaagg caattttttt agtctcttta tttacatcca acacataaac ttctacttct
    11821 tgtccctctg aaacaacatc ttcaacactt tcaactcttg tccaagctaa attatttata
    11881 tgtgctaatc cttcaatccc accaatatcc acaaatgcac cataaggcat tatctttgtc
    11941 accttaccat ctcttttttg tccaacttca agagaattaa ataagtcttc tttagctgct
    12001 ttgatacgag ctttttcttc ttctctttct tgcttaattc ttgctctttc agcttctttt
    12061 tctgccttaa tttgagctct tctttcttct ctctctttat ttatacgctc ttgtaataca
    12121 tctctatgag atgctacaag tctatttttt ctaacatcca attcttttat ataaacttct
    12181 aagttaagac caacaaattt agatgtatct gtaataaatt ttgtatcaag ttgagaaatt
    12241 ggtataaaaa atgtatatgt attgtaatta gcaaatacac ctttatctat attcttttca
    12301 acatttacag ttattattct atgttcatca taagcctttt gtaactcggc aaaatcattt
    12361 cttttgtcaa gttgtaattt agataaagtt attgtaccat ctttttgaga tacttttgtt
    12421 attacagcag ttatttcatc acctatgtgg tatatatctt ctatatattg atttttttct
    12481 atgttcaatt cacttatagg tattattcca tcaaacccat agtctaatcc taattgtact
    12541 tcatcatttc tcactgcagt tatttttcca gttgtcaatt ctccaacttt cactttgctg
    12601 aatacttgtt cttgctggtc aagtaattct tgcattgtta aatcattttc cattataaac
    12661 atcctttcct cttattgatt atcatatctg taaatattat accattaata ttgcaaatac
    12721 ttacattttt cttactataa tttttaaaat aaattcaact tcatatattt atacattata
    12781 gaaaatatct tattaaatta aaatacaaat tctaattttt atctaataaa atattttcat
    12841 aaaaaattta tattgtatat cttattcttt tattgcttta ggttttgata gaaaacattt
    12901 ataaaatata aagaaagaaa ttgctgttat agtagcagct gttatatctg caactggctc
    12961 tgctaaaatt actgcaaaaa gtttttcatt aaagaatgtt ggaagtataa atattaaagg
    13021 tattaaaagt acaatctttc taagtagagc taaaaccaaa gatattgttg cttttccaag
    13081 tgctaaaaat gtctgttgac aagctatttg aatcccaaac ataaaagcac cagcaaaata
    13141 tatttttata ctccaactag tcatactaag taactgcgga ttcttattaa atatactaac
    13201 aaaaaatgca ggaaatatca ttaataaaag ccataaaata gtagaatatg taaaacatga
    13261 caacaaacac aacttaaatg tcttttttac tctatcaagt tgacctgaac cataattata
    13321 acttattatt ggttgtgctc cttgtgtaac ccccatatta ggaagcataa gaatttgcat
    13381 tatactgctc attatagcca ttgaacctac tgctaaatct cctccataca tttgtaattt
    13441 actatttaag gctataagta ctaaactttc tgtagattgc attataaatg gagagattcc
    13501 caaaccaagc actggtaaga tgatacttgc ttttggtatc atatacttct tttttatttt
    13561 aagtatactt ttctttccaa agagaaacat aagtacccaa atagcagaaa cgccttgtgc
    13621 aattatagta gctaatgcag ctccttttac acccatatta aagccaaata taaaaatcgg
    13681 gtcaagtatt atgtttatta aagcacctat agcaactgtc atcattccag ttgtagcaaa
    13741 cccttgggta tttataaaag tattcatacc cattgaaatc tgaacaaaca ctgtacctat
    13801 taaataaata tttaaatagt ccattgaata tccaattgta gattcacttg ctccaaacat
    13861 ccaaagtaaa ggctcttttc caatcttaaa acctatagtc aaaagtattg ctaaaatcac
    13921 cagtacagaa aaactgttac tcattatttt ctctgcctca tcattgtttt gctcacccat
    13981 ttttatagca gctaatggac ctcctcccat accgattaaa taactacatg cagttattat
    14041 aattattatt ggaaatgcca ctccaacacc agccatagca acttctccat tttccattct
    14101 accaataaaa atcctatcga ctatgttgta taaaacattt acaatttgtg cgataatagc
    14161 aggtgtagca agtttaaata ataatttacc cacactttca ctacctaagt tagtgtttga
    14221 attttccatt ttaaaacctc ctcaatccaa taattaaaat gtatcactaa aattttattc
    14281 tatataaaaa tttcatttta ttagcagaca aatttagagt actttcccta caagtaatac
    14341 tatactatat ttcttttgcc atagtaaaca ttttagaact aactgaagtt aaatacttta
    14401 tctcattttt tatttattat taaaaatttt tcacacatac tcataaaaaa actatccaag
    14461 tatattactt agatagtttt atattatatg taaagaaaga gctgaaacta taacccctga
    14521 taacaaattg ccaagaaata ctcccataaa agcatctttt attctcattt ttaatatgga
    14581 agctatagca gatgcagtcc acgttcctgt agttggcagt ggtataccta caaatagtat
    14641 tataccaatt atcgaaacac tttttaattt cttcattctt gagtttattt ttctatcaat
    14701 tacatcagca atccctttaa atagtttctt ccctcttaaa aattgtaata catgtctgaa
    14761 tgtcaatatc aagggaatcg ataccaatgt agaacctatt acactaaata cataaaccca
    14821 tataggattt aagcccattg caatacctat aggaatggct cccctcaatt ctgttacagg
    14881 aaccatagat aaaattaata tgtgtaaata tcccaaacta ttccctccta ttctaagtga
    14941 cattaagtta tgaatttatt tgctctataa cctcaccatc ctttttacta actaaaaatg
    15001 catttttagt caatgaaagc attggtaaat cactcttaga gtctgaatat gcatatgaat
    15061 tttcataatc aatctctatc ccaagtttac ctaatacagc ctttattctt tttacttttt
    15121 caattccctt acagttttct ccaatgaatt tatttttata tcttgaattt tcataaaaaa
    15181 actccgtgcc tataacctcg tctgcaagac cataatactt aaaatatttc atatatgcat
    15241 atggagatgc agttatcata attataacat tatcttcttc tttatttttg taaataacct
    15301 ttttcataga ttcgttaatt tttttcatta tgcaatcatc aaaaaacttt tttaaatctt
    15361 cttcactaaa atctactatt ggataaaaga ttgcctcttt tgccttcttc aatggtatta
    15421 ttctaattaa atacataaat agaataaaaa taatgtatgg taactttata atagttttaa
    15481 aggttttatt ttttaaagag taaataaaaa aatctatcat gctatcagta tttataacag
    15541 tataatctac atcaagtaat aatacacttt ttttcataag tatttcccca tcctatcact
    15601 aaaaatatca ctaaaaaatc aatattatta aacatgtaat tatccataag attacgttta
    15661 tttttaaagc attatctttt aagacaatat cagtaggatt attttcattt gtagtgttaa
    15721 ttatataatt atatctaagt acaccataaa ctacaaatat tgttgtaaat atcatatgtg
    15781 gcttttctgg attacttgta gaatacaatg cataacatac aattgtagaa cttaatataa
    15841 ctatcatcat ttgatttaga ttttctatgt cataatcttc caatattttt ctatgttcaa
    15901 ctgcatcatc tcttagagtt tctatttctt ttttacgttt tccaagagct aagtacagag
    15961 ataagaaaaa tgtacataaa attatccaat ttgataaact aacacttatg gctacacatc
    16021 ctgcataaac cctaagtata aaaccaagag atattgaaaa cacatctaat agtattatat
    16081 tctttagttt aagagaatat aatatattgt ttatcaaata gagactgaga attatagaaa
    16141 gattaaaact aacaactgtt gataaacaga ctgaaattaa agctaatact acaaatagta
    16201 tattagcact ttttttgctt attcttccac ttgccactgg tctattacat tttttaggat
    16261 gttttttatc tttatccatg tctatagcat cattcagtgc atatactgat gatgacatta
    16321 gacaaaaaca cacaaacgca ataaacgtat ttaaaaataa atttatattt agtatgttgt
    16381 ttgaaaaaat tatagctgaa aatacaaaga aattctttat atattgcttt attctcatta
    16441 actttatata atctgaaatt ttagtaagaa gccttatact tgtattggtc tgtttcataa
    16501 acttactacc ctttcaatat tattttttaa acaggatatg attttatccc tatgtttaaa
    16561 atttctataa atccattgac attactgatt actatagtaa ccaataacag cgatagaaat
    16621 atattataca tattcttttc attttttcta agcgctttcg taaagtaagc caataaaatt
    16681 ataactgcaa aactaaaatt tatagccata atacttgaat tgactagatt atatcctact
    16741 ataccatgta aagttagatt gaatataatt attcccatac atagcttagg aactcttttt
    16801 tctgaatttt caataactga taaaacacaa aaacataaag ctaataatgt aagaattact
    16861 ggtattgtag caacttctcc attttgcaaa aataaccctt ttttaatact tgctccagga
    16921 aaataaaaaa ccgaatacaa taatctctct ataatcattg caatcttttc caaaattggt
    16981 tctccactta taaatttcgt atcatactgt attacatttc caaggttcat aaaactctca
    17041 taagactttg ttgaaactac acaaatatat gccattagga taaatgtaat taaatgtttt
    17101 aacatttttc ctatttttaa tttaaactca aatatcatat taaaaaaata caaatatata
    17161 ttactaatag ttattccaaa tagaggaata gctgctaatt ctactaaata agaatttttt
    17221 cctttcatct tatttgcaat aactatgaaa aatattaatg aaaattggct atatataaat
    17281 ctctctacat ttaaagtcat aaataactgt ggaaaagaaa atatcattat catagtaagt
    17341 aaaattaaag ttaatctctg catttttatc tttttaatat gattaaagac taaagttatt
    17401 gacatagcac tagttattat ttgtagacaa attagtccaa acccataggc actattaaaa
    17461 tctgttgtcc caggatttgc tattgaagta caaaataggt atattggata tgcaaaaatt
    17521 gatataattg ctgaaaacaa tatgtgctta ctattgtctt gacttatagc aaatacattt
    17581 aaattgaata aaactcctgt atctgtatct aacaatacat cataagtatt gtttaaatca
    17641 taaaatatag tagtcttaga aaaaaatatc ttagttatta ttaagtaagt tattacaact
    17701 aatataaaca aaaacatctc gtttttatat tttaatattt tactcatcaa tatatcacca
    17761 tccattcatt atataggatt tgctgacacc tacaatttat tccttatatt taatagccat
    17821 cttcataatg ttcttacttg ttttattgta attgaataac tctttattta caaccacaat
    17881 atttacttta ttgatgttat aatcagtcaa gtattgttta tataacatag attagtgttg
    17941 tataaaatga gaatttgtaa gcaatattaa tgtaaaatat ttgaaaaact ttatataaaa
    18001 atatacaatg ttgcttatgg aattaaacta taacaaatta aagcataatt taaggagaca
    18061 aaattataat ctgtctcctt aaatattaaa actatatttt aaaacattac taaatactat
    18121 acaaatttca aatatagtat aaaattaatt agactttaac actattagct ccatcttctt
    18181 cccatttttt aatttctttt aatctatcta ttataggtaa atgctgagta cattcaactt
    18241 cacattttcc acaagatata cattctttag cttttgcctt actattcatt gtgtaattcc
    18301 aatgtcctaa gccataaact aactttgtca tttcttcatc actcttttta aacatctgct
    18361 tttcattata aaaaagcata taggctgggg tattaatacc ttttggacat actttacaat
    18421 aaccacaacc tgtacatatt tcgttcatat tcttatttaa tctagtctca atatcatgta
    18481 tatcctcatc tgaataaatt ctattttcgt ctgcaatttt acatgcatca tctatatctt
    18541 gttttttatt aaaccctatc aaagatatac ttatttgtga aattcctatg ttgaatctta
    18601 aagctgattc tatagtactt tcgccatctt ttgatagaaa agaaagttct ttattatact
    18661 ttggaatagt tccaccactt aatgggttca ttgccacaac accatatcca ttatcaacag
    18721 catatttggc accttttagc ctatatggaa agtttaatat atttattccc atagttacac
    18781 cttcaaactt attttcactt agaatatcta taacctcatc tcctggttga tgagatgaaa
    18841 atactatatg gtctatcaat ccttcttctt tacatttcaa taatccttca tattgacctc
    18901 caggtctcat tgctagttcg taatgttcca tctttctaat attccaaaca tgataaaaat
    18961 ttattttaga tacgcctaat cgttctattg atttttttac agcctctata gctttttctg
    19021 atgtatcaca tgcttttggc ttttctttag ttgatacata aaaatcggtc ttaccttcct
    19081 ttatcatttg tctaaaggct agtccaaata tatcttcact tctgtcatca caataccctg
    19141 gtgctgtatc aaagtaatta ataccttttt catacgcata tttgactaaa tcagcatttt
    19201 cttgattact tttttctaaa tcaaacctta atcctccata gccaactact gaaaccattt
    19261 tccctgtctt tccatattca acgtatctca ttgtaaattc ctccttagat atattaagac
    19321 ttaatttctt tatagaaaat attataccat aaataatttt tataaattat ttatggtata
    19381 atattttttt tataaattat atttttttat aacttgtatt ttataactaa gttaaaaact
    19441 ataaaaaggt tcaatatgga ctattacttg agcattttca ttaatttctt cttgtatttg
    19501 tttctcaatt ttatgtgtta aatcatgaga ttgctctacg cttataaatg ggtctaccat
    19561 tacatgcatg tcaatataaa tagaactttt gctacctcta cttctgatat tgtgaacatc
    19621 ccttacctca ttaaattcaa acacaatttc ttttatataa tcctcatcta cagccactct
    19681 atcgaccaaa attccaatag atggcctaaa tattccataa gccgaataaa ttatgaatgc
    19741 agaaataata ataggaacta tagattctat tattactgga aatcctaact taacaccaac
    19801 taaagtaacc aatacaccta gagacacaaa tatatcactt cttgtatgca atgaatccga
    19861 aatcaaaaca taactattta gtttagtccc aattctatat tcatacatgc atacaaaaat
    19921 atttataaaa agtgtaataa ttaaagcaat taaactttct atagttatag caggtacaac
    19981 tggattagct attcttaaca ctgcactaag aattatctta attgctataa caaacaacat
    20041 accacttata aataaactgg ttataatttc aaacttttta tgtccataag gatgattttt
    20101 atcttttggt ttagatgcaa agaaaatacc tataagcccc actatattag atgctccatc
    20161 tgacaaagaa tgaaatccgt ctgctgtcat actatagctt tttatttgat taccaataat
    20221 gatttttaat aatgctactg caaaattagc aaataaaatt atccacaata cttgcttcac
    20281 tttcttatag ttatccataa caaattcccc ctcccttcga ttcaataaag aaagctatct
    20341 atcaatatca atcaaccaga caataaaatc gtatataagc acatttacta tatttatatt
    20401 caaaattggt tgtacttgtt cattctattt gaaacttaat tataaataaa aatcgtaggt
    20461 atggttttgg tatacataaa aataagagac tgtctcaaaa taaagataat cttctttttt
    20521 attgttgaaa tgataaaata tatttgattt catataaaaa agagtgcctc atgaactaaa
    20581 aagttcattt tgagacactc ccttaaattt ttgatataaa ctattaattt tttatactaa
    20641 gccttcttta actaagaatg aatgagcaac ttcttctggt gatttaccaa gttcatccac
    20701 ttgatagtta agttctctca tagtttcttc atttattttt cctgaaagca tattcataac
    20761 tttttctaac tcaggatatt tcttcaaagt atcttctctt actaatggtg ctgcataata
    20821 tggtacaaag aaatttttat cgtcctctaa tatcttaaga ttaaactttt taataagacc
    20881 atcagttaaa aatgcatcta taacctgaga ttcattatta tctaaagctg tatatcttaa
    20941 acttccattc attgctttta catctttgaa ttttaaacca taatctctag aaagccctac
    21001 aagaccatct tctctatttt caaactccaa agttggtgag aatgtaaatt ctttaccata
    21061 tttagtcaaa tcagaaatag tatttattcc atacttttca gcagtttcag gcatcatagc
    21121 taatgtgtaa gtattattaa atccaagagg gtcaagtaaa gttaactgat tttctttttc
    21181 catagtatct tttacaacat tatatgcttc atcagcatct ttaatcggag catgtttcat
    21241 tacatttacc aaaagtgtac ctgtatagtc aacatacatg tctaactcac cagatttaat
    21301 tgcattaaac gcaacagatg aaccacctag atttaaattc ttcttaactt taagattcgt
    21361 atttttttct actaattcag cataaacatt gccaagtata agttgttctg tataatcttt
    21421 agaaccaata gttattgtat cttttttact tgaaaaacta gaactaaaaa caacgaacaa
    21481 cattgaaaca acaagcacta cagatattac tttaagtgct atataattct tcttaggtgc
    21541 ttttggattt aatccttttg gagtaactgc aacttcaatt ttactaaata aataatcaac
    21601 taacagtgca attatacatg atgggattgc ccctgctaaa atcatattat tatttacagt
    21661 ttgaacccct gaaaatacta aatatcccaa accaccagca cctataaatg ctgcaagagt
    21721 catcaaacca acagctgtaa ctgcagatat tctaactcca cccattatta taggaagcgc
    21781 taaaggaaat tgtattttaa ataatgtctg atttcttgta agaccaatac ctttagctga
    21841 ttctaatact actgggtcaa tacttgttat acctatatac gtatttttta caattggtag
    21901 taatgaataa accactacca taaatatggc tggtttactt cctataccaa gtataggtac
    21961 aagaagaccc aaaagtgcca tagacggaac tgcttggact aagtttacaa atccaagtac
    22021 aaactttcta agagatgaga ttcttgaaat aattattcca agaggaacac caactattat
    22081 agctattaaa atagatgtaa cagttagact catatgttgt attaaaagct ctataatctt
    22141 atctttttgt aatagtataa agttaaaaaa attagccaag aacactcacc tccatttcta
    22201 agaattgttc acttaaaaca gaaagtaaac tacttctagt aataagccct accagtttat
    22261 tttcatcaga aataaccgga atatatccaa ccgaattacg attcattaca tttagtattt
    22321 ctactaaatt atcaccttca tttacatgca aaggctcact tgacataata tcagcaagta
    22381 atattgactt atcatcaata tctttcatat cttttacagt aacaatacct tttaatgttt
    22441 ttgctctatc tataattagt aagctatcaa ccttactcgt tctcataatt tctattcctt
    22501 gagttacagt tctagtagaa ttaacagcaa taggattttt tatcataata tctcttgctt
    22561 ttatatattc tggattatcc caaactctat cttctccgat aaaatctttt acaaagtcat
    22621 ttgcaggctt tctaagtata ttttcgggag tatcatattg tgctattctt ccatccttca
    22681 taatacaaat tttatcagct atctttaaag cctcatccat atcatgagtt acaaatatta
    22741 tagttttttt caattcatct tgaagagaaa ataattgttc ttgtaaagat gttctcgtta
    22801 ttgggtctaa agcactaaaa ggctcatcca tcaatattat ttcagcatca gtagcaatgg
    22861 ctcttgcaac accgattctt tgttgctgtc caccactaag ttctgaagga tacttattca
    22921 aaaattcatc actatcaagt cctaccatct caagtagttg caacgttctt ttttcaattt
    22981 cttcaacgga tttttccttt tttaggcgtg gaattagctc tatattttct tttattgtaa
    23041 gatgagggaa taggcctgtg ttctgtataa catatcctat ttttcttcta agctctattt
    23101 cattttcctg agaaattggt ttgccattaa tatatatctc accagatgta ggttttatta
    23161 atttgtttat aagcttcaaa gtagtagtct ttccacaacc acttgaacca atcaaaacta
    23221 ccaatgtacc tgtttctaca actagagaaa tatcatctaa tataacatta tttcctattt
    23281 tttttgttac atttcttatc tctatcataa tttatcatcc cctttttcga acaagcaacc
    23341 ttcttcaata ttataagttg tttttataat tatatcatac tattttattt atgtaaacaa
    23401 agtacgattt ttaggtcact atttgtctga atattgctac aaatataaag tatttatata
    23461 tagtatataa tacataatgt caaaaaacaa aaaatataaa aatattcata aaataacact
    23521 agcctcaatt atatagtatt aaagctagtg ttatttcatt taaacaaaac tcacatttgg
    23581 atactatcca tgtattcaaa taatgtaata tctttataag tttctttttt atcacttagg
    23641 tttgatattg taactcccaa tagcctaatt tgttttccat taacatcaac atttctcaac
    23701 aaattatcta caccacttct tatatcatta tattcgtcaa tatagtgttc taaactaagg
    23761 cttctagtta tctttgtaaa gtcctcatat ttaattttta atgttaatgt ttttccaaac
    23821 ttctcagagt tttttaatct atgacatact tcttcacaaa gttcatcaag aatgttgcgt
    23881 gtttcttctt catcaatatc caaattatga cttaatgtag tctcagcccc aacagatttt
    23941 ctaaccctat ttggttccac tggtctatcg tctattcctc tagcaaattt atataattca
    24001 taacctcttt ttttgaatat attttcaagt tcaaataaat ttaaacacct taaatcatat
    24061 ccagttttta tacctaaatt tttaagagta tttgaagtaa cttttccaac accaaaaaat
    24121 ttattcacag gtaatttatc taaaaagtcc tgggcatttt cttcggttat tacagttaac
    24181 ccatttggct ttcttaagtc tgatgcaatc ttagcaagaa acttattgta tgacacacca
    24241 gctgaagaag taagaccaac ttctctaaat atatcttttt ttatttgctt tgctatctca
    24301 attgatgaat caatattttt tttatttttt gttacatcta agtaagcttc atctaaagat
    24361 aatggttcaa ctaaatccgt gtatctataa aatatatctc ttatttgctc tgacacactc
    24421 ttataaacat caaatcgagg tcttacaaaa actgcatatg gacacctatt gtaagctaca
    24481 gctgatggca tagctgaatg gataccaaat tttctagctt cataagaaca cgttgcaacc
    24541 acacctcggc tttgtggatt tccaccgaca ataacaggtc ttccttttaa ttttttatta
    24601 tctctttgtt ctatagatgc ataaaaagcg tccatatcta tatgaattat ttttctataa
    24661 tgtttcatta ttatcacctt ttaaagtata aatagattaa ttttatttat attacttttt
    24721 aattatacca aacttatgtt tctttttggt attttttcat tattttcttt atatattcat
    24781 attttccata aataaaacca tctataatcc attaacttca atataattta taaaaaatcc
    24841 ttaaaaacac ttgcaaaaac tatataaaag ctttacaata ggtattccaa ggaactaaat
    24901 ttaaaattcc ttatggataa cagtatatat atttaattta tgggatgttt taaaaacaaa
    24961 agactgtctt atgcaagaca gcctactgat tttattataa ttgtaatgga ctgctcaaac
    25021 tattacttta aaacagccca tattttttta tataatttta actatagtaa agattttgtg
    25081 aaggatattc tgggtcacaa gttacatcta taccaagctt tctaaatgtt tgttcatcat
    25141 ctctatttaa tatagtagta gaatgagctt gacacccttt taataatgct aacttttcca
    25201 tagcaaattg tgcagttgga ttagttacag cacaaatact aagtgcagtt aacacctctt
    25261 ggcaactaag tgaaacattt ctactagcta aagtctttgt ttttaagttt atgataggtt
    25321 ctaatattac aggtgatatt aagtgcatat catcagatat attggctaaa tgtttaatgg
    25381 catttaatac tactgctgca gttccattca ttaaatcaga acccttacca gttaatattg
    25441 taccatcttc taattctaat gcaactacag gacaagtatc attcttgtca gcactttctt
    25501 tcaatttatt actgtagttt ctagcaggta atacaacatt tctatcttct ggctttaagt
    25561 taagctcttc cataatcatt ttcattctat cataagcacc tttatcaact tgtccctttt
    25621 tatactcaca ggcagtttta aagtatcttc ttattatttc ttctatagaa gcttttctta
    25681 ttacttcatc atctattatt ccaaagccaa ctctattaac acccatatca gttggagatt
    25741 ggaaaattga ttcttttcca gttatctttt ctattatttt tttaagcact ggaaataatt
    25801 ccaaatctct attgtagttt actgacattt caccatacgt ttcaaggtgg aatgaatcta
    25861 tcatattcac atcttttaaa tcaactgtag ctgcttcata agctatattc aaaggatgtt
    25921 ttacaggtac attccaaact gggaatgtct caaacttaga atatccaact acattacctc
    25981 ttttattttc atgatacaac tgacttagac aagtaccaag ttttccacta ttaggtcctg
    26041 gtgctgtgac tactactatt ggctttgtag tttctatata ttcatttgct ccatatccct
    26101 catcactaac tatagtctca acatctgacg gatatccctt tgttggataa tgcttataaa
    26161 ctttaattcc tctacgttct aatttattta taaatacagt tgtagcaggt tgtccttcaa
    26221 atctagtaat tactacacta tttacatcta gttcataacc tcttaaatca tctattaatc
    26281 ttaaaacttc catatcataa gtgataccaa agtctcctct tattttgttt ctttctatat
    26341 ctcctgcata gacacaaatt acaacttcaa ctttttcttt catatgttgt aatactttta
    26401 tctttgcatt ttcatcaaat cctggaagta ctctttttgc atgaaggtct cccatcaatt
    26461 ttcctccaaa ctctaaataa agtttgtcaa aattatttac tctttctaag atatatttag
    26521 actgctcttc taaatatttt ttgtggtcaa atcctacttt catcttaaca cctcactaaa
    26581 ttaaatttct tattgataac agtatattta tatatatttt tttagtaaaa catcttataa
    26641 aaaaatgtta atactttttc actcaaagta atattataca attaagatta atttttttca
    26701 agat
//
LOCUS       DAJMZY010000050        26388 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.050, whole genome shotgun sequence.
ACCESSION   DAJMZY010000050 DAJMZY010000000
VERSION     DAJMZY010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 26388)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26388)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26388
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.050"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            38..877
                     /locus_tag="OE968_002050"
     CDS             38..877
                     /locus_tag="OE968_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HCP7219329.1"
                     /translation="MFGIDKKLIEYIIAKSNYSELSSKSAEVSFFLMLSIFPFLIFTI
                     SSIAYIPILHLNKYIALFRNMMPEGAFAVLSSIIVSAIDNRNLKFLAVSFVLTMWTFS
                     RAVKALIKGMNRAYKVKETRSFFKILSISFLFTIMLLVLIFLSMIFLVYGEKIGYFIF
                     NLVGLDEIFIKIWDILRYTVGIITIIVIFTLLYKYTPNKKLTIKESAPGAIFATFAWF
                     LVSFLYSYYTNYYANYEVIYGSIAEIIVLMTWMYFSSWSIVIGYEVNSRLYFRKIRHE
                     MLK"
     gene            1394..3250
                     /locus_tag="OE968_002051"
     CDS             1394..3250
                     /locus_tag="OE968_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing protein"
                     /protein_id="HCP7219330.1"
                     /translation="MDTHNKYVNFIKNIPVPFLYCRIVKRQEDIEYRVEYISKGMGKV
                     LQLEEGICDKNILDVLPVFKSKKYFKELFSNEVDCIKRYIPTLKNWINIKKQIIGDSY
                     IILYFGKIVFDYRQIIDSFDKKEKVAYIKDEEGIYIDCSENLIPILNNNIKTTKDIFG
                     KNDIEVWGENTGKLFRDDYREGVSSKKRFLQNLFEYEETFFMVEKYFLYDEDELLGTI
                     GIVDNIIYSGYSNRNYNSKDLMKMIEHSIPENMFYKDVYGNYIGFNSGFLNLACMNKE
                     ELLGKNSYKISEEEALIDKIFESDKGVVENKKVVTFELNISMNDENKCIEITKRPFFD
                     SYGSVIGIIGTARDISRRKRLEEEMDKTRMEFFANLSHELRTPINLISSSLQVIEKKE
                     ADLIESNDTLKRNLGIIKQNGNRILRLVNNVIDFTKMQSGYLDFKPEESDIIAFIEEI
                     CMSVADFASQNNIQLTFDTEIEEFSMLFDSEKLERIILNLLSNGIKYNKKDGKINIFL
                     YVKDNVFNMKISDSGIGIPKEKIDKIFNRFEQIDNELSYRVKGSGIGLSLVKSLVELH
                     EGSISLKSQLGIGSEFIVSLPVRSKNNIEKYNHKREISNELSKKLEIEFSDL"
     misc_binding    3333..3573
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     misc_binding    3639..3874
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            3959..5176
                     /locus_tag="OE968_002052"
     CDS             3959..5176
                     /locus_tag="OE968_002052"
                     /EC_number="1.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HCP7219331.1"
                     /translation="MENKVKIGVLGYGVVGSGLIDIIDNNKEKRNIEIVGILVNNLEK
                     HKDKKYSNIITNNIDDIFNKDIDILVEVMGGLEPSLSYIKKALNNKIHVVTANKDLLA
                     ECGDELAKLASENKVSIKFEASVAGGIPVLKPIIESLEGNNIDSINAILNGTTNFILS
                     KMYDENLSYDMALRQAQELGFAEANPESDVLGYDAARKLSILSTLAYDNRVYWKDVYL
                     EGITDIDEKDIEYAKKLNCKIKLIGQSKYENDKVSAFVRPVLVEKDNILARIDNEFNA
                     VIVNGDSVGEVSFVGKGAGSLATGSAVYSDVIDIIDNRVSSIDSFTKDKIQVNKIVRE
                     KCGALLRFKKCNKDEILNIVENCLVKFDILNDDDELAIMVYADSEYEINNSLCLIKDK
                     GYCEKMNKMLKIS"
     gene            5293..5787
                     /gene="cdeM"
                     /locus_tag="OE968_002053"
     CDS             5293..5787
                     /gene="cdeM"
                     /locus_tag="OE968_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exosporium morphogenetic protein CdeM"
                     /protein_id="HCP7219332.1"
                     /translation="MENKKYANGGYSEDWYERGESTAKWFQNDREEYERAAYDEDRER
                     RGSNCGCSDSGENRPRNCERFRREAEIREREAREAFCESSERKKEALAYECEARKLWE
                     EAEKYWDEYSKYNYKGIEYLAEAARLFDEGMECEARRNGNNGGNNNNCCHKCHKCNCN
                     CCRK"
     gene            6052..7317
                     /gene="hisD"
                     /locus_tag="OE968_002054"
     CDS             6052..7317
                     /gene="hisD"
                     /locus_tag="OE968_002054"
                     /EC_number="1.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol dehydrogenase"
                     /protein_id="HCP7219333.1"
                     /translation="MKSIKTSSMKEKVDEKILREQVSSIIEDIRNNKDVALKKYNEKF
                     DRNTRDEFRITKEEIKEAYKHVDDEFINNLKIAAKNIREFAKAQKLSFENPFEKEIYP
                     GVILGQTNIPIESCLAYVPGGQYPLFSTALMLIIPAKVAGVKRIVACSPTMKNTEKIN
                     PKTLVAMDIAGADEIYATGGVQAIAAFTYGTEKINPVDIIVGPGNKFVTEAKRQCYGQ
                     VGIDFVAGPSEVLIIADETSNPVYIAADLLAQCEHDLNARGILLTNSLEVAQKVEKNI
                     ESMLKDLPTKDIAYSSWENNGEIILVDDMEEAIKISNFYAPEHLEVAVNEYNDICDRL
                     TNYGSLFIGNLSAEVFGDYVSGTNHTLPTLKASRYTGGVWVGTFIKTCTKQIFNEKAI
                     QSLAPVAEKLAKEEGLYAHAKAAEVRFKK"
     gene            complement(7520..8272)
                     /locus_tag="OE968_002055"
     CDS             complement(7520..8272)
                     /locus_tag="OE968_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HCP7219334.1"
                     /translation="MSYFQYQGNSCFYKEYGQGKPIIFLHGNTGSSNMFKALVPLYVE
                     NFRCILIDFLGNGQSDRVSQFSPDIWHDEALQTIALIEHLNCGKVGLIGTSGGAWAAV
                     NTGLERPDLVEAIIADSFDGRTLNDNFIDNLITGREKSKQDIQARKFYEWCHGKDWEN
                     VVNLDTKALLQCANEKRPLFHKELCKLEMPILFTGSKEDEMCRHNLEEEYKQMATFIS
                     KASIHIFSQGGHPAILTNADEFAQLAKVFFKY"
     gene            complement(8390..8659)
                     /locus_tag="OE968_002056"
     CDS             complement(8390..8659)
                     /locus_tag="OE968_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219335.1"
                     /translation="MSYQNSIDLLPKELIEQVQEYIDGKVIYIPKKQEHKKHWGENTN
                     TKQVLASRNSQICINFQNGMSIKQLSEKYFLTEKSIQRILKQQNL"
     gene            9134..10228
                     /locus_tag="OE968_002057"
     CDS             9134..10228
                     /locus_tag="OE968_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HCP7219336.1"
                     /translation="MKNIVGKPQTIKKVNEDLIKNIIKNEGPITKPEISNITELSLAT
                     VNKIVEQLALKNEVKVSGLSESTGGRRAQLFEINANLEHIIALYYYRNCCIGVVANLL
                     GEIIYQEEFNIRMDTYENVNQDTFFVIDTLIKKEKGNNIRAIGIGVPGVVKKGVVKNI
                     PTIKSWEGINLENLIKSKYNTKVFIENDTNITTIGIYQKQYKDKYKNMALMYLEDGIG
                     SGIVINGELYLGSTNFAGELSYLNIEFGKYNSNNLNLEDYIMSLRKRYLESKDNKFKK
                     EILSIISNFIRTLVCVLNPQAMIIQCSILTKSDMEFIEKDVSNNVGEENFPKLIKVES
                     LREGSINGVISMCLKETDYQYSLSNKKGGY"
     gene            10230..11180
                     /locus_tag="OE968_002058"
     CDS             10230..11180
                     /locus_tag="OE968_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine kinase"
                     /protein_id="HCP7219337.1"
                     /translation="MKYLVSIDGGGTKTKFCVSDLDGNILKEHTTGSTNYKSVGIKKT
                     YENINNGFKKILKDLYIDYDDIEYTVFGISGCDSPNDYKIIMDEILKIGINKEKIYLA
                     NDAVLAFYAQADSPGLVIVAGTGSIILGIKEDGEIYRVGGWGYNFSDLGSGYDIGRKL
                     LKKVLLYCDECHEYSDLFSCVLDFFGANSFEQLAYMITDINNNVEIANLASLVIDCAE
                     QGDKLAIEILRESSTELSKLAQVILRKISNPMKVDKSEINIVLSGGTLNKTVYAQMLM
                     NNLKTENTDKNLKFISQENQPVYGGIRLAMALANRRVKHG"
     gene            11173..12357
                     /locus_tag="OE968_002059"
     CDS             11173..12357
                     /locus_tag="OE968_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219338.1"
                     /translation="MDRKKVIVQIFTGGFKAKEIKFNDIKCKLLELLDCIDIEKVIMG
                     WSVDEELYVETKKLLNKYNVELYLWLPCFSEIGLLEKSNLLIDYMGKEVKGYALQEDE
                     NFEFYCPNNKENIKNIKKIYSTYFSDIKFDGIFLDKIRYGSFSNKLNGVFNCFCKDCL
                     NIYEKNNIDKESLMREMNNVSKGVIDNEDTPFGITEYINGKYKFKNKIWEDFFETKNQ
                     NIYKALLEISNYFKSKGLKIGIDTFSPFISYFTGQDLEKLQEVADFIKPMMYRTTKAP
                     AGLPFEFERFIDESIHKNKEIGKRNFLDILGIKEYEGDVYPIEFVLEEIDFMTRNLNK
                     DIYVGVEINKKEIISPVTPKYISENISNINKTTVKGYVLSWDLLSAPKENIDEIIKWF
                     RN"
     gene            12370..13866
                     /locus_tag="OE968_002060"
     CDS             12370..13866
                     /locus_tag="OE968_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HCP7219339.1"
                     /translation="MSKILEMQQIYKSFGKVDVLKGINFELEKGEVRALLGANGAGKS
                     TLIKILGGVHSQTKGKVILTGNEIMFKNPHHSKENGISIIYQELSLIPTLTVLENIFL
                     GREILKGSVFLNKKDMLEECMKICEDFDFNIDPHMVVSNLSVANQQMVEIMKAVSCNS
                     EIIIMDEPTTSLTNNEKDGLFKIISRLKSKGKTIVYISHILEEVFKVCDSASIMKNGI
                     MIGTYDVEDLTKLKITQLMTGNDNHKLIEKKDYTFAKYEEPPVLEVKNISWSNKIKNV
                     SFKVYRGEVVGLAGLVGSRRTEIINLIFGIDNKDSGDIFINGKKVDITSPKVAIKNKI
                     GLIPEDRKNLGLILEQAIYTNSSSVQIDKFKKFLFIDRNKEIEFSKKGVKELGIKVND
                     VKQEVKELSGGNQQKVVVSKWLEKDLDLIIYDEPTKGIDIAAKEDIFNTIKEFSSKGI
                     GVIFISSDLEEVIRVSDRILVTREGSIVDDLKNENIQVQDIMNSIFNV"
     gene            13889..14839
                     /locus_tag="OE968_002061"
     CDS             13889..14839
                     /locus_tag="OE968_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCP7219340.1"
                     /translation="MKKAFEKLNLRDYGVLLGFLALCIAISIATPSFLGKQNILNLLR
                     QSSIIGIISAGMTFVIISGNFDISVGAVAALAGAITMKFATGGTNLFASMLLGVAICA
                     VIGLINGIVVAKINVPSLIATMAMVTIVRGLLLMLTGGYPITENIPILDYIGNGYLFN
                     IPIPVVIFFIVVLASFIVLNKTKFGRYVYSVGGNQEASKLNGINVDSHKVKVFIINAV
                     LAGIAGIVLTGRLGTATAIAGEGYDMDAIASVVIGGTSVAGGSGSVLKTVIGVLLMSV
                     INNSFNLLGIDVYFQYIFKGLIILAAVGFDSYSKKKLASR"
     gene            14860..15822
                     /locus_tag="OE968_002062"
     CDS             14860..15822
                     /locus_tag="OE968_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HCP7219341.1"
                     /translation="MKKLMKHLALLLSLVMIFGLVGCSNGGDKEKNGEKKIAVLLPGS
                     TGYFVATKQGIDAKSKELGVSVEYADAQWDASKQLSQAEDFMAKGVDMIALCGVDSAV
                     SERIVKAANDSDVPIVAFTNSIGSNPTGEFKGLVTYIGQNEEETGALTGKIAKNLLGE
                     TGGKAVLIEGVPGTTPQVLRKKGLEKELKDSNIEIVYNQTSNWEKEQALKVTEDLIQK
                     KTDFNVIICQDDNSATGAGQALKDAGLKDKVKVIGLGGSKDGLKAITDGLIDGTTYMS
                     AVEEGGLVIEKASKFLKGEKIEPVTQIKQVEVNKDNISEFKGEW"
     gene            16194..16826
                     /locus_tag="OE968_002063"
     CDS             16194..16826
                     /locus_tag="OE968_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HCP7219342.1"
                     /translation="MARRLFLERIGLIFLGSAILAFGVYNFYYLNNITEGGVLGILLL
                     LKNLFNIQPAIANVVIDGLLLLVGYKFFGKKFLIYSIVASITFSVLYDLFEAIGPLVP
                     QSQNMLLSTILAGVTVGTGVGIVVKAGCASGGDDALALVISKTTSLNIGQVYLATDVI
                     VLLLSLFYLSAFDIFYSLIAVTISGKVIDFIYYHGKSLDMDISNDIVPEC"
     gene            17237..17329
                     /gene="kdpF"
                     /locus_tag="OE968_002064"
     CDS             17237..17329
                     /gene="kdpF"
                     /locus_tag="OE968_002064"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: protein motif:HMM:TIGR02115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="K(+)-transporting ATPase subunit F"
                     /protein_id="HCP7219343.1"
                     /translation="MEGLPMWFLAVVIIMLIIYLVYALINPEKF"
     gene            17370..19052
                     /gene="kdpA"
                     /locus_tag="OE968_002065"
     CDS             17370..19052
                     /gene="kdpA"
                     /locus_tag="OE968_002065"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015391009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium-transporting ATPase subunit KdpA"
                     /protein_id="HCP7219344.1"
                     /translation="MFMVQIVIVLAIFMILVIPMGKYLYHIATNQKTFGDRLFDKVDN
                     FIYKVCSIDKKKEMNWKQYALALLFTNAVMVFIGYIILRTQSMHIFNPSGIKSMEQGL
                     SFNTIISFMTNTNLQHYSGESGLSYFSQMTVIIYMMFTSAATGYAAAMAFVRGLVGKK
                     KTLGNFYVDLIRITTRVLLPGALIIGLILVTQGVPQTFAGTETVTTIEGKLQDIARGP
                     VAALESIKHLGTNGGGFFGSNSSHPFENPTIISNIVEILSMMILPGACVVAFGHMIKN
                     KKQGWVVFGAMSIIFLIGLVVCFKAESAGNPILSQLGLNQSMGSMEGKEVRFGIAQSS
                     LFTTVTTSFTTGTVNNMHDTLTPLGGLVPLLNMMLNVVFGGKGVGLMNMLMYAIIAVF
                     LCGLMVGRTPEFLTKKIEGKEMKLIALLIILHPLLILMFSGLSVAIPAGLEGISNPGF
                     HGLSQVLYEFASSAANNGSGFEGLGDNTMFWNITTGIVMFFGRYVSIIVLLAISSLLA
                     SKKAVNESIGTLRTDNFTFTIVLVLVVLIVGALTFFPALALGPISEHLVLWH"
     gene            19077..21134
                     /gene="kdpB"
                     /locus_tag="OE968_002066"
     CDS             19077..21134
                     /gene="kdpB"
                     /locus_tag="OE968_002066"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010966942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium-transporting ATPase subunit KdpB"
                     /protein_id="HCP7219345.1"
                     /translation="METKKTKFITKDIFKTSIIEAFKKLNPKYMMKNPVMFVVEIGFI
                     VTLILTIVPSLFGDEGNNLRAYNGIVTIILFITVLFANFAEAVAEGRGKAQADTLKKT
                     RKDTVARVIDTLGNEKMISASELKLGDIVLVNAGEVIPNDGEVIEGIASVDESAITGE
                     SAPVMRESGGDFASVTGGTTVVSDWLKIRITTKPGESFLDKMIALVEGASRQKTPNEI
                     ALNTLLVGLTLIFMVVLISLYPMANYAGVKIPISTMIALLVCLIPTTIGGLLSAIGIA
                     GMDRVTRFNVIAMSGKAVEACGDVDTMILDKTGTITYGNRLASEFIAVGNADSKDLIN
                     YSVMCSLKDDTPEGKSIVDLGMKLGSTGKTKEAEEAEFVEFSAQTRMSGINLADGRAI
                     RKGAYDSIIKRVKESGGTVPEDLEENVNRVAKLGGTPLVVCVDNEIYGIIYLKDTVKS
                     GLVERFARLREIGIKTIMCTGDNPLTAATIAREAGVDGFIAECKPEDKIDAIKKEQLE
                     GKIVAMTGDGTNDAPALAQADVGLAMNSGTTSAKEAANMVDLDSDPTKILEVVEIGKQ
                     LLITRGALTTFSIANDVAKYFAIIPAIFTLAIPQMEILNVMKLSTSFSAILSALIFNA
                     IIIPCLIPLAMKGVKYRPMKSQAMLMRNMLIFGLGGVIVPFLGIKLIDLLITPLVMVL
                     NLG"
     gene            21153..21779
                     /locus_tag="OE968_002067"
     CDS             21153..21779
                     /locus_tag="OE968_002067"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="K(+)-transporting ATPase subunit C"
                     /protein_id="HCP7219346.1"
                     /translation="MKTLKPALLVSIVLLVVCGLVYPLVLTGVSQVAFKDKANGSMIE
                     VNGVKVGSELIGQSFTDARFFKGRVSSVNYNTYTKEDLVPDKDGNTSYGGVSSGSFNY
                     GATNPELHDRVQKDIEQFLKDNPTVKREDIPTDLLTASGSGLDPNISPASAKIQIPAI
                     AKASGISESKLQKIVEDNTSKKLFGVLGEDRVNVLKVNVEVAKILGLI"
     gene            22016..22924
                     /gene="cysK"
                     /locus_tag="OE968_002068"
     CDS             22016..22924
                     /gene="cysK"
                     /locus_tag="OE968_002068"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HCP7219347.1"
                     /translation="MLYNNALELIGNTPVVRLNNLGCTNGCSNIYVKLEKVNPAGSIK
                     DRAVYEMLEGLEQRGELKKGDVLVEATSGNTGIALSMIGKLKGYEVVIVMPETMSVER
                     RDLMKAYGANLVLTDGKAGMAGSIEKANELLKENPNYKSLKQFENKDNPNAHYKTTAV
                     EIMNDVKDLDIFVCGVGTGGTLIGTARYLKEQNPNIRVIALEPKKSPAISENKTGPHK
                     IQGIGANFVPENYDSSVVDEVILVDDEDAFDTVKLLAAKEGILVGISSGANIFGAIEM
                     AKKYPDKKIVTVAPDGVDKYMSMGIF"
     gene            22951..23541
                     /gene="cysE"
                     /locus_tag="OE968_002069"
     CDS             22951..23541
                     /gene="cysE"
                     /locus_tag="OE968_002069"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HCP7219348.1"
                     /translation="MFKKINKDIEYIMKNDPAARSKIEVFLLYPSVHAMIMHRMAHAL
                     YKKKKLFTARLISQISRFMTGIEIHPGAKMGEGILIDHGMGVVIGETAEVGNRVTIYQ
                     GATLGATGKDTGKRHPTVGDDVLIGAGTKILGPLNIGSNSKIGANSVVVKDVPNGATV
                     VGIPAKIVKIRNLEPVKKNKKEVSYEYDELDNVYYI"
     gene            23701..23889
                     /locus_tag="OE968_002070"
     CDS             23701..23889
                     /locus_tag="OE968_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HCP7219349.1"
                     /translation="MKANVNQDTCIGCGLCPSICPEVFDMKDDGKSHVIVDEVPSDAE
                     ESAAEARESCPVDAIDVH"
     gene            complement(23943..24812)
                     /locus_tag="OE968_002071"
     CDS             complement(23943..24812)
                     /locus_tag="OE968_002071"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HCP7219350.1"
                     /translation="MKLNRNDSCWCGSTKKYKKCHMDMDNKIDSFAKLGHIVPTHDII
                     KNESQIEEIKKSAVINTKILDYISDKIEIGMSTEDINKLVHDFTLQNGAIPAPLDYNG
                     FPKSVCTSVNNEVCHGIPSKDIILKDGDIINVDVSTIFNGYYSDASRMFMIGNVNENA
                     KKLVQVTKECVQKGLEVAKPWGFLGDIGDVINSYAKKNGYSVVREIGGHGVGLSFHED
                     PFVSYVSKKGTEMLLVPGMIFTIEPMVNEGTHEIFVDEENNWTIYTKDGKLSAQWECM
                     VLVTETGVEILTE"
     gene            complement(25009..26253)
                     /locus_tag="OE968_002072"
     CDS             complement(25009..26253)
                     /locus_tag="OE968_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219351.1"
                     /translation="MENNLNTAKRNNTELLQNDSLKVNLQIGVDFTLLSKSLKAFYKK
                     EKDFYCIALAPCNVSSEKANRKISIYNMIKEINILIESITDKNELLSEELFTNNLSEF
                     YDESLDEIYIDLKQAYLYIKKNTDSLNIEDSIEYVFDVDISNDIKAKENPLINFNSLS
                     LVVWSGETKHILQQMNILDLEDIHSYSIENNTNITIYENNTLQYKFDEESENIKDSSI
                     DIIEQMLILPDDLNYDKDEVENMKNRLAKINIKYLQTLKEKDIKIKLINSNLTDEPEF
                     SDLKYQLPPCWVRSGKTWKDVPGIYRNNSIVAKIGYSNPSYANVHSSKNLELHETAHA
                     IDKNVLNKKSNSEEFMEVFAQERYKLYDPKQVAHAYISKFIEEFFAESFVHYYLDEDS
                     KNTLKENCPLTYDFLEKLELNY"
BASE COUNT        10128 a         2804 c         4717 g         8739 t
ORIGIN      
        1 gtataatgaa attaatttga tagaaaaggg gatatttatg tttggtatag ataagaaatt
       61 gattgaatat ataattgcaa aatccaatta cagtgaatta agttcaaagt cagcagaagt
      121 atctttcttc ttaatgttgt ccatatttcc ttttttaata tttacaataa gttctatagc
      181 ttatataccg attcttcatt taaataagta tatagctttg tttagaaata tgatgccaga
      241 aggtgctttt gctgtgttat cttcaatcat agtttctgca atagacaata gaaacctgaa
      301 atttttagca gtcagttttg tacttactat gtggacattt tcaagagcag taaaagctct
      361 tattaaagga atgaatagag cctataaagt taaagaaact aggtcttttt ttaaaatttt
      421 atctatatca tttttattta caataatgct tttggtcctt atttttttat ctatgatatt
      481 tttagtttac ggtgaaaaaa taggttattt tatttttaat cttgtaggat tggatgagat
      541 atttataaaa atatgggata ttctaagata cactgtaggt ataataacaa taatagtgat
      601 atttacactt ttatataaat acactccaaa taaaaagtta actattaaag aatctgcgcc
      661 aggtgctatt tttgctactt ttgcttggtt tttagtatca tttttatatt cttattatac
      721 aaattactat gctaactatg aagtaatcta tggaagtata gctgaaataa ttgtacttat
      781 gacctggatg tattttagta gttggtctat cgttattggc tatgaggtaa attcaagatt
      841 gtattttaga aagataagac atgaaatgtt aaagtaaagt atttaaaata aaagagagta
      901 tttagtatta taaatgtaat tgaattaata aagaaatatt gacatttaag ttaaaaagtc
      961 tagaattttt ctgggctttt tttattttta gtataacttg acaaatttta tttaatggga
     1021 tagttttaat ttataatcat ctttaaaaag atgactattg ataagtaaga gataaaattg
     1081 gtaagtatca aaaaatatac taaataaaaa ttatagtcct aatgagttaa tttctgtatt
     1141 ttcaaataat gcagtattta gtcatgtgtt tttatatgcg cctgtatttc taattagcaa
     1201 tatattagaa taagctactg taattagatt tagaaaaaag cgacataaat aattataaac
     1261 aaataataaa ttacataaaa ttaaatttat tcacaagtat atcttataaa atatgttata
     1321 attaatagaa aattgtcata taattaatta agtagtatta ttataaataa cattgaaagg
     1381 tagtggttag aatatggata cccataataa atatgtaaat tttataaaaa atatacctgt
     1441 acctttttta tattgtagaa ttgtaaagag acaagaagat atagaatatc gagtagaata
     1501 tataagtaag ggtatgggca aagtattaca attagaagaa ggtatttgtg ataaaaatat
     1561 actagatgta ttgcctgtat ttaagtctaa aaaatatttc aaagagttgt tctcaaatga
     1621 agtggattgt ataaaaaggt acattccgac acttaaaaac tggataaata taaaaaaaca
     1681 gataataggg gattcataca taattttgta ttttggtaaa attgtatttg attatagaca
     1741 gataatcgat tcctttgata aaaaggaaaa agtagcttat attaaagacg aagaaggcat
     1801 atatatagat tgtagtgaaa atttaatacc aatattaaat aacaacatta aaacaacgaa
     1861 agatatcttt ggtaaaaatg atatagaagt atggggagag aatacaggaa aattatttag
     1921 agatgattat agagaaggag tatctagtaa aaaaagattt ttacaaaatc tttttgaata
     1981 tgaagaaaca ttttttatgg ttgaaaaata ttttttgtat gatgaagacg aacttttagg
     2041 tactataggg atagtagaca atataatata tagtggttac agtaatagaa attataactc
     2101 aaaagattta atgaagatga tagaacactc aattccagag aatatgtttt ataaagatgt
     2161 gtatggaaat tatattggat ttaattcagg ttttttgaat ttagcttgta tgaataaaga
     2221 agaattatta gggaagaata gttataaaat atcagaagaa gaagctttaa tagataagat
     2281 atttgaaagt gataagggtg tagttgaaaa taaaaaagta gttacatttg agttaaatat
     2341 aagtatgaat gatgaaaaca agtgtattga gattacaaaa aggccgtttt ttgatagcta
     2401 tggaagtgtt attggaataa ttggaacagc aagggatata agtagaagaa aaagattaga
     2461 agaggaaatg gataaaacta ggatggaatt ttttgcaaat ttatcccatg aacttagaac
     2521 gcctataaat ttaatatcat cttcattaca agtgatagaa aaaaaagaag cagatttaat
     2581 agaatcaaat gatactttaa aaagaaatct aggtataata aaacaaaatg gaaatagaat
     2641 attgaggtta gtaaataatg ttatagactt tacaaaaatg caatcaggat atttagattt
     2701 taaaccagaa gaatctgata taattgcatt tatagaggag atatgtatgt ctgtagctga
     2761 ttttgcaagc caaaataata tacaacttac atttgataca gaaatagaag aattttcaat
     2821 gttatttgat tcagaaaaat tggaaagaat aatattaaat ttactttcta atggaattaa
     2881 gtacaataag aaagatggaa aaataaatat atttttatat gtgaaagata atgtatttaa
     2941 tatgaaaata tctgatagtg gtataggtat accaaaagaa aaaatagata aaatatttaa
     3001 taggtttgaa cagattgaca atgaactttc ttacagagtt aaaggaagtg gtattggact
     3061 ttcattagtg aaatctttgg ttgagttgca tgagggaagt atatctttaa aaagtcaact
     3121 tggtattgga agtgaattta tagtttcatt gcctgttaga agtaaaaata atattgaaaa
     3181 atataatcat aaaagagaaa tcagcaatga actaagtaaa aaattagaaa tagagttctc
     3241 ggatttataa gtttaaatat aaaaaataaa attttaaaaa agtattgaca attgatttag
     3301 aagggtttaa aataaattac aacataataa ataaaaaggc gatgaatagg aagagtaaat
     3361 ctaattcgat taccagagag aagagtccgt tggctggaag actttttaaa ttagagggat
     3421 tgaaaactac ctaggagcta ctttctgaag tcatctgcat tagtagattt tagtaagaat
     3481 agtcgttagc tgcgttaaag tgtaaagtga gttttcatga catatgaaaa ctaaattagg
     3541 tggaaccgcg ggaataatac tctcgtcctt atgttataag gatgagagtt ttttgttatt
     3601 taaaaatata aacagtaatc ataataatta tagaaaatat aaaagcaatg aataggaaga
     3661 gtaaatttaa ttcgactatc agagaggaaa gttcacaggc tgaaagactt tctaagtttg
     3721 agaaattgaa aactacctag gagctgtggt ctgaagttac tttaaaaagt tttagtaaga
     3781 ctaaccgtta actgcgttaa agtgtaaagt ggattttatc aataaatgat aaaatcaaat
     3841 tgggtggaac cgcgagtata gactcgtccc tttatatagg gatgagtcta tttttattgc
     3901 aataaaagat tgaaaataaa aaaaaatcgg aaaattataa atttaggagg aaaataaaat
     3961 ggagaataaa gtgaaaattg gagtactagg atatggagtt gtaggaagtg gacttataga
     4021 tataatagat aataataaag aaaaaagaaa tatagaaata gttggaattt tagttaataa
     4081 tttggaaaaa cataaggata aaaaatattc taatataata actaataata tagatgatat
     4141 atttaataaa gatatagata tacttgttga agtcatgggt ggtttagaac catcattatc
     4201 ttatataaaa aaagcattaa acaataaaat tcatgttgtt acagcaaata aagatttgtt
     4261 agctgaatgt ggagatgagc ttgcaaaatt agcaagtgaa aataaagtaa gtattaaatt
     4321 tgaagcttca gttgcaggag gtataccagt attaaaacca ataatagaat cactagaagg
     4381 aaataatata gatagtataa atgcaatttt aaatggaact actaatttta tattatctaa
     4441 aatgtatgat gagaatctat cttatgatat ggcattaaga caagctcaag aattaggttt
     4501 tgctgaagca aatccagagt cagatgtatt agggtatgat gctgctagaa aactatcaat
     4561 attatcaact ctagcttatg acaatagagt atattggaag gatgtgtatt tagaaggaat
     4621 tacagatata gatgaaaaag atattgaata tgcaaaaaaa ttaaattgta aaataaaatt
     4681 gattggtcaa agtaagtatg aaaatgataa agtaagtgct tttgttagac ctgttttagt
     4741 agaaaaagat aatatccttg ctagaataga caatgagttc aatgctgtca tagtgaatgg
     4801 agattcagta ggagaagttt cttttgtagg taaaggcgct ggaagtttag caacaggaag
     4861 tgcggtttat tcagatgtta tagatataat agataataga gtttcaagta tagattcttt
     4921 tactaaagat aaaatacaag ttaataaaat agttagagaa aagtgtggag cacttcttag
     4981 atttaaaaaa tgtaataaag atgaaattct aaatatagtt gagaattgtt tagtaaaatt
     5041 cgatatttta aatgatgatg atgaacttgc tattatggtt tatgctgatt ctgaatatga
     5101 aataaacaac agtttatgtc taataaaaga taaaggatac tgcgaaaaaa tgaataaaat
     5161 gttgaaaata agttaaaaaa gaaaaaatat aagtttatat gtaacatatt ttgacgattt
     5221 taatactata tagtatgaga tgaaacaaaa catctcataa aaaaattaaa attcaaggga
     5281 gagatatgtt atatggaaaa taaaaaatat gcaaatggtg gttattcaga agactggtat
     5341 gaaagaggag aatctacagc taaatggttc cagaatgata gagaagaata tgaaagagca
     5401 gcatacgatg aagatagaga aagaagaggc tcaaactgtg gatgttcaga ttcaggagaa
     5461 aatagaccta gaaactgtga aagatttaga agagaagcag agataagaga aagagaagca
     5521 agagaagcat tctgtgaatc ttcagagaga aagaaagaag cactagcata tgaatgtgaa
     5581 gctagaaaat tatgggaaga agcagaaaaa tactgggatg aatattcaaa atacaactat
     5641 aaaggaatcg aatatttagc agaagctgct agattatttg atgaaggtat ggaatgtgaa
     5701 gctagaagaa atggaaataa tggaggaaac aataataatt gttgccataa atgccataaa
     5761 tgtaattgta actgctgtag aaaataaaaa aattaattga caaatcaata gttaaaatat
     5821 atcatattat gtataataaa gagaaaattc agaaaaaaat aatgattaga agaaatataa
     5881 gtatatttat tagacaaata gtgctcagtt agtgaggtga gtacaatatg attaaactcc
     5941 catcctctag cttttgatag agggtgggag tttttattta tttatatatc ttaaatgagg
     6001 ataatattgt aaaataaatg agtatgagat tgtaaaatta ggaggtaaaa aatgaagagt
     6061 attaaaacat caagtatgaa agaaaaggta gatgaaaaga tattaagaga gcaagtaagt
     6121 tctataatag aagatataag aaataataag gatgttgcac ttaaaaaata taatgagaag
     6181 tttgatagaa atacaagaga tgaatttaga attactaagg aagaaataaa ggaagcttat
     6241 aagcatgtag atgacgaatt tataaataac ttaaagattg ctgccaaaaa tataagagaa
     6301 tttgctaaag ctcaaaaact aagttttgaa aacccttttg aaaaagaaat ttatccaggt
     6361 gtaatcttag gtcaaactaa tattccaata gagtcatgtc ttgcatatgt tccaggaggt
     6421 cagtatccat tgttttcaac agctcttatg cttataatac ctgcaaaagt agcaggagta
     6481 aaaagaatag tggcatgttc accaactatg aaaaatactg aaaagataaa tcctaagaca
     6541 ttggtagcta tggatatagc aggtgctgat gaaatatatg caactggagg agttcaagct
     6601 atagcagcat ttacatatgg aacagaaaag attaatccag ttgacataat tgtaggacca
     6661 ggaaataagt ttgtaactga agctaaaaga caatgttatg gacaagtagg gattgatttt
     6721 gtcgctgggc caagtgaagt tcttataata gcggatgaaa cttcaaatcc agtttatatt
     6781 gcagctgatt tattagcaca atgtgagcat gatttaaatg caagaggaat attattgaca
     6841 aatagcttgg aagtagcaca aaaagttgaa aaaaatatag aaagtatgct aaaagatttg
     6901 ccaacaaagg acatagcata tagttcatgg gaaaataatg gagagataat attggttgat
     6961 gatatggaag aagccattaa aataagtaat ttttatgcac cagaacattt agaagttgca
     7021 gtaaatgagt ataatgatat ttgtgataga ttaactaact atggttcttt atttattgga
     7081 aatctttctg ctgaggtgtt tggtgactat gtttcaggta ccaatcatac attaccaaca
     7141 cttaaagcat caagatatac tggtggtgtt tgggttggaa cttttatcaa aacttgtaca
     7201 aagcagatat ttaatgaaaa agctatacaa tcattagcac ctgtagctga aaagctggca
     7261 aaagaagagg gattatatgc acatgcaaag gctgctgagg ttaggtttaa aaagtagtaa
     7321 aaaattttat tttggcagtc gagatttagt gttagactga gataaggaaa acgctgagaa
     7381 cccgaataaa tactatattt tgtgggcctc ggcgtttctt ttatatctgt atataatagg
     7441 ataatactac ctgtgtgttt aaatgctagc ttaatatttc ttttctaaat aatgtttatg
     7501 aaatagttaa tatttttagt taatacttga aaaaaacttt tgctaactgt gcaaattcat
     7561 ctgcattcgt caatatagca gggtgtcctc cctgactaaa aatgtgaata cttgcttttg
     7621 aaataaaagt tgccatttgt ttgtactctt cttcaagatt atgacgacac atttcgtctt
     7681 ccttacttcc tgtaaataaa attggcattt ctaatttaca caattcttta tgaaacaaag
     7741 ggcgtttctc gtttgcacat tgcaatagag cttttgtatc aagattaaca acattctccc
     7801 aatcttttcc atgacaccat tcatagaatt ttcgtgcttg aatatcttgc tttgattttt
     7861 cccttccagt gattagatta tctatgaagt tatcattaag agtacgtcca tcaaagctat
     7921 ctgctataat tgcttcaact aaatcgggac gttctaatcc agtattaaca gctgcccatg
     7981 ctcctccact tgttccaatt aagccaactt taccacaatt caaatgttca atcaatgcta
     8041 ttgtctgtaa ggcttcatca tgccatatgt caggagaaaa ttgagaaact ctatccgact
     8101 gtccattacc taaaaaatca attaagatac atctaaaatt ttctacatat aatggcacaa
     8161 gtgctttaaa catattagaa gaaccagtat taccatgcag gaaaattatc ggtttacctt
     8221 gtccatattc tttataaaaa caagaattac cttgatactg aaaatatgac atatattttc
     8281 ctccttttta tttgttaagt taattataac aatataggta tgaatgaaaa acctcatgtt
     8341 ctttcttaga ataaaaatgt gccacgcata aaacgtgaca catttctaat tataaatttt
     8401 gctgtttaag tattctttgt atgcttttct ctgtcaaaaa gtatttctct gataactgct
     8461 tgatactcat tccattttgg aaatttatac agatttgaga attacgagaa gctaagactt
     8521 gtttggtgtt tgtgttttca ccccaatgct ttttgtgctc ttgctttttg ggaatataaa
     8581 tcactttacc atctatatat tcttgcactt gctcaatcag ttctttaggc agtaagtcaa
     8641 tcgaattttg atagctcatt ttgcacctcc taaataatta ttctttagga ttagcaaagg
     8701 ctactgccac tcacaattaa aaataaaatt ttttattatg tacaatagcc tttgctatgc
     8761 acaagttcca attcccataa actaaatact cctttctggt ttgaaaaatt catctgaaca
     8821 ttgatttcgc ttttaagata gagttcaatg acaaatttac atttttatta tatatattca
     8881 gatagataat tgcaactgtc tttgtatgag gatattttat tatagtcaat actataatat
     8941 gtatttatat catcaaacta atatgaacag ttgaaaggaa tatgaacaat aaaacttagt
     9001 caggaagaat aattatgaag cagacaatag agaaatttga ttttaaagtt ttattgaaaa
     9061 tttattgaca aatttaactt gtaaatatta tactaaactt aataaataaa gtttataaag
     9121 taaggtgttg tctatgaaaa atatagttgg aaaaccgcaa acgataaaaa aagtaaatga
     9181 agatttaata aaaaatatta taaaaaatga aggtcctata acaaaaccag aaatttcaaa
     9241 cattactgaa ttgagtttag ctacagttaa taagattgta gagcaattag ctttgaaaaa
     9301 tgaagttaaa gtaagtggac taagtgaatc tactggagga agaagagctc aattatttga
     9361 aataaatgca aacttagaac acataatagc tttatattat tatagaaatt gttgtatagg
     9421 ggtagttgcc aatttattag gtgaaataat ttatcaagaa gaatttaata taagaatgga
     9481 tacatatgaa aacgttaacc aagatacttt ttttgttata gatactctaa taaaaaagga
     9541 aaaaggaaac aatataaggg ctattggaat tggtgtccca ggagttgtaa aaaaaggtgt
     9601 agttaaaaat ataccaacta taaaaagttg ggaaggtata aatttagaaa atttaataaa
     9661 gagtaaatac aatactaaag tgtttataga aaatgataca aatattacta ctattgggat
     9721 ttatcaaaaa cagtataaag acaaatataa aaatatggct cttatgtatt tagaagatgg
     9781 tattggttca ggtatagtta taaatggtga attgtattta ggttctacaa attttgctgg
     9841 agagttaagt tatctaaata tagaatttgg taagtataac tctaacaact taaatcttga
     9901 agattatatt atgagtttaa gaaaaagata tttagaaagt aaagataata aatttaagaa
     9961 agaaatttta tctataatat caaactttat aaggactctt gtatgtgtcc taaatccaca
    10021 agctatgatt atacagtgta gtatattaac caagagtgac atggagttta tagaaaaaga
    10081 tgtaagcaat aatgttggag aagaaaattt tcctaaatta ataaaagtag agtcattgag
    10141 agaaggaagt ataaatggag taattagtat gtgtttaaaa gaaactgact atcaatattc
    10201 cttatctaat aaaaaaggag gatattaatg tgaaatattt ggtttcaata gatggagggg
    10261 gaacaaaaac taaattttgt gtaagtgact tagatggaaa catacttaaa gaacatacca
    10321 ctggttcaac taattataag tcagttggaa ttaaaaaaac atatgaaaat attaataatg
    10381 gatttaaaaa aatattaaaa gatttatata tcgattatga cgatattgag tacactgtat
    10441 ttggtatatc tggttgtgat tctcctaatg attataagat tataatggat gaaatattaa
    10501 aaattgggat taacaaagaa aaaatatatc tggcaaatga tgcagtttta gctttttatg
    10561 cacaagcgga ttcccctggt ttagtaattg tggctgggac aggttcaatt atactgggaa
    10621 ttaaagaaga tggagaaata tatagagttg gtggatgggg gtataatttt agtgatttgg
    10681 gttctggata tgatataggg agaaaattat taaagaaagt attgctttat tgtgatgaat
    10741 gtcatgagta tagtgattta tttagttgtg tcttggattt ctttggagca aatagttttg
    10801 aacaacttgc atatatgatt actgatataa acaataatgt tgaaatagca aacttagctt
    10861 cattagtgat tgattgtgcc gaacaaggtg ataaattggc tattgaaata ttaagagaat
    10921 catcaactga actatctaaa ttagctcaag taatattgag aaaaatatct aatccaatga
    10981 aagtggataa aagcgaaata aatatagttt tgtctggtgg tacattaaat aaaactgtat
    11041 atgctcaaat gttaatgaat aatttaaaaa cagaaaatac agataaaaat ttaaaattta
    11101 tatctcaaga aaatcagcca gtgtatgggg ggataagact tgctatggca ttagctaata
    11161 ggagggtcaa gcatggatag aaaaaaggta atagtacaaa tttttactgg aggttttaag
    11221 gctaaagaaa taaagtttaa tgatataaaa tgtaaactac tagaattatt ggactgtatt
    11281 gatatagaaa aggttatcat gggatggagt gtagatgaag aattatatgt agaaactaaa
    11341 aaactattaa ataaatataa tgttgaacta tatctttggt tgccatgttt ttctgaaata
    11401 ggattacttg aaaaaagtaa tttgctaatt gattatatgg ggaaggaagt caagggctat
    11461 gctttacaag aggatgaaaa ttttgagttt tattgcccaa ataataagga aaatataaaa
    11521 aatataaaga aaatatatag tacttatttt agtgatatta aatttgatgg aattttttta
    11581 gataaaataa ggtatggttc tttttcgaat aaactaaatg gtgtttttaa ttgtttttgt
    11641 aaagattgtt taaatatata tgaaaaaaat aatattgata aagagtcgtt aatgagagaa
    11701 atgaataatg tgtctaaggg agttatagat aatgaagata ctccatttgg tataacagaa
    11761 tacattaatg gaaaatacaa atttaaaaat aaaatatggg aagatttttt tgaaacaaaa
    11821 aatcaaaata tatacaaggc attattagag ataagtaatt attttaaaag taagggattg
    11881 aaaataggta tagatacttt ttctcctttt atttcttact ttacaggtca agatttagaa
    11941 aaattacaag aagtagcaga ttttataaaa ccaatgatgt atagaactac aaaagctcca
    12001 gctggtttac catttgaatt tgaaaggttt attgatgaat ccatacataa gaataaagag
    12061 attggaaaaa gaaatttctt agatatttta ggaattaagg agtatgaagg agatgtatat
    12121 cctatagaat ttgtactaga ggaaatcgat tttatgacaa gaaatcttaa taaagatata
    12181 tatgtaggag ttgaaataaa taaaaaggaa attatatctc ctgttacacc taagtacata
    12241 agtgaaaata tttcaaatat aaataagaca acagtaaaag gatatgtttt atcttgggat
    12301 ttgttgtcag caccaaaaga aaatattgat gaaattataa aatggtttcg gaattagtga
    12361 ggtgataaag tgagtaagat attggaaatg caacaaatat ataaaagttt tggaaaggta
    12421 gatgttttaa aagggataaa ttttgagtta gaaaagggag aagtaagagc tcttttggga
    12481 gctaatggag caggaaaatc tacacttatt aaaattttag gaggagttca ttctcaaact
    12541 aaaggtaaag taattttgac tggtaatgaa ataatgttta aaaatccaca tcattctaaa
    12601 gaaaatggta ttagtataat ttatcaagaa ttaagcttga taccaacgct tacagtactt
    12661 gaaaatattt ttcttggtag agaaatttta aaaggaagtg tgtttttaaa caagaaagac
    12721 atgcttgagg aatgtatgaa aatttgtgag gattttgatt ttaatataga cccacatatg
    12781 gtagtttcta atttaagtgt agcaaaccaa caaatggttg agataatgaa agctgtttca
    12841 tgtaattctg aaattatcat aatggatgaa cctacaacat cacttactaa taatgaaaaa
    12901 gatgggctat ttaaaataat aagtagacta aagtctaaag gtaaaacaat agtctatatt
    12961 tctcacatat tagaggaagt ttttaaagta tgtgatagtg caagtataat gaaaaatgga
    13021 attatgattg gaacttatga tgtagaggat ttaactaaat taaagataac tcaacttatg
    13081 acaggaaatg ataatcacaa acttattgag aagaaggatt atacatttgc aaaatatgaa
    13141 gagccaccag tactagaagt aaagaatata agctggtcta acaaaataaa aaatgtttca
    13201 tttaaagttt atagaggcga agttgtaggt cttgcaggtc ttgtaggttc aagaagaact
    13261 gaaattataa atttgatatt tggtatagat aataaagata gtggagacat ttttatcaat
    13321 ggtaaaaaag tagacataac ttctcctaag gttgctataa aaaacaaaat aggattgatt
    13381 cctgaagata gaaaaaatct aggattaatt ttagaacaag ctatatacac aaactcatca
    13441 tcagtacaaa ttgataaatt caagaaattc ttgtttatag atagaaataa agaaattgag
    13501 ttttctaaaa aaggtgttaa ggaattagga ataaaagtta atgatgtaaa gcaagaagta
    13561 aaagagctta gtggtggaaa tcaacaaaaa gtagtagttt ctaagtggtt agagaaagat
    13621 ttagatttaa taatatatga tgagccgaca aagggaatag atattgctgc aaaagaagat
    13681 attttcaata caatcaaaga attttcaagt aaaggaatag gagtaatatt tatatcttct
    13741 gatttagaag aagtaataag agtaagtgat agaattttag taactagaga aggttctatt
    13801 gtagatgatt taaaaaatga gaatatacag gttcaagata taatgaacag tatatttaat
    13861 gtataaaaaa tgaaaatgga ggactgaaat gaagaaagct tttgagaagt taaatttaag
    13921 agattatgga gtattattag gttttttagc tttatgtata gctataagta ttgcaactcc
    13981 atcattttta ggtaaacaaa atatacttaa tcttttacga caatcttcta taattggaat
    14041 aatttcagca ggtatgactt ttgttataat atctggaaac tttgatatat cagttggagc
    14101 agtagcagct cttgcaggtg ctataacaat gaaatttgcg actggtggaa ctaatttgtt
    14161 tgcatccatg ctcttaggtg tagcgatttg tgcagtaata ggattaatca atggtatagt
    14221 agttgcaaag ataaatgtac catcattaat agccactatg gctatggtca ctattgtaag
    14281 aggattgctg ttgatgctta caggaggata tccaattact gaaaatatac caatacttga
    14341 ttacattgga aatggatatt tgtttaatat accaatacca gtagtaattt tctttatagt
    14401 ggtgttagct tcatttattg tacttaataa aactaagttt ggtagatatg tttattctgt
    14461 aggagggaat caagaagcaa gtaaacttaa tggtataaat gtagattctc acaaagtgaa
    14521 agtatttatt attaatgctg tacttgcagg aatagctgga atcgtactaa caggaagact
    14581 tgggactgca actgcgattg caggtgaagg atatgatatg gatgcaattg catctgtagt
    14641 aataggaggt acatcagtgg caggaggttc tggttctgta cttaaaactg ttataggagt
    14701 attacttatg agtgttataa acaacagttt taatcttctt ggaatagatg tatatttcca
    14761 gtacatattt aaaggattaa taattttagc agcagttgga tttgattctt atagcaagaa
    14821 aaaacttgct tcaagataaa aaataagggg gattttttta tgaaaaaatt aatgaaacat
    14881 ttagcattgt tgctatcact tgttatgata tttggtttag ttggttgttc aaatggtggt
    14941 gacaaagaaa aaaatggaga aaagaaaata gcagtattac taccaggttc aacaggttac
    15001 tttgtagcaa ctaaacaagg tatagatgca aaatctaaag aattaggtgt aagcgtggaa
    15061 tatgcagatg ctcaatggga tgctagtaaa caattatcac aagctgaaga ttttatggct
    15121 aaaggggtag acatgattgc attatgtgga gttgattctg ctgtaagtga gagaatagtt
    15181 aaagctgcta atgattcaga cgttcctata gtagcattta caaattctat aggaagtaac
    15241 ccaactggag aatttaaagg tttagttaca tatataggac aaaatgagga agaaacagga
    15301 gcattaactg gaaaaattgc taaaaactta ttaggagaaa ctggtgggaa agctgtatta
    15361 atagaaggag taccaggaac tactccacaa gtattaagaa aaaaaggtct tgaaaaagaa
    15421 ttaaaagata gtaatataga aatagtttat aatcaaactt caaattggga gaaagagcaa
    15481 gctttaaagg taacagaaga tttaattcaa aagaaaactg attttaatgt tataatatgt
    15541 caagatgata attctgctac aggtgcaggt caagctttaa aagatgctgg tcttaaggat
    15601 aaagttaaag tcataggttt gggtggaagt aaagatggat taaaagctat aactgatggg
    15661 ttaatagatg gtacaactta tatgtctgct gtagaagaag gtggattagt catagaaaag
    15721 gcatctaaat tccttaaagg tgaaaaaata gaacctgtta cacaaattaa acaagttgaa
    15781 gttaacaaag ataatatttc agagttcaag ggtgaatggt aaattgtcat agataataaa
    15841 taagattttt agagttactt tagaaactat ataaagtaac tcttttttta atttaattta
    15901 gtgataaatt attgaatagt atttctaaac aaataaaaaa ttaatataaa caaagactta
    15961 attatactaa attataagta aaactaatat aaacttatgg aaaaaaggaa aacgtctaaa
    16021 gtattggaat tactatagtg taggtgtggt attaaaaaaa cataaaaaaa cataaaaaaa
    16081 ttgttgaaaa aaatatagaa attttgtata attaaagatt tgaaaagtgc ggtatacaaa
    16141 gccaattctt ttgtatataa tatatataaa ttcagaaaaa ggaagggata tgtatggcca
    16201 ggcggttatt tttagaaagg attggactta tatttttagg ttcagcaata ttagcatttg
    16261 gagtttataa tttttattat ttaaacaaca taacagaagg tggagtgtta ggtattttac
    16321 tactgttaaa aaatttattc aatatacaac cagcaatagc aaatgttgta atagatggtt
    16381 tgctactttt agtaggatat aaatttttcg gtaaaaaatt ccttatatat tcaatagtag
    16441 cttctataac tttttcagtg ttatatgact tatttgaagc tataggacct ctagtaccac
    16501 aatcacaaaa tatgctttta tcaactattt tggcaggtgt aactgttgga actggtgtag
    16561 gtatagtagt aaaagcaggt tgtgcatcag gaggagacga tgctttagca ttagtaattt
    16621 ctaagactac atctttgaac atagggcaag tttatttagc aacagatgtt attgtattgt
    16681 tgttatcatt attttatcta tcagcgtttg atatctttta ttctttgatt gctgttacaa
    16741 ttagtggcaa ggtaattgat tttatttatt atcatggtaa aagtttggat atggatataa
    16801 gtaatgatat agttccagaa tgttaatata aattaaataa ctttagattt tattaggggt
    16861 ggcagatttg ccaccttttt tgtgtctaaa tctttataga aagtataatc ctatctaggt
    16921 ttttgcaaat ctcaaatata gaattatgtt gaaatgactg ggaatacgat tgctagatgt
    16981 gcattttaaa aacccaattt tatatttatg aaatactaat cattaatgga tgtttcttaa
    17041 tcctatcttt atacctaaaa tgataagata aatgaagtag caatacaaaa ctaaaatttg
    17101 taaaagagat taaattaaat ggaggagcta aaatgttgga tatagttatg atagcattgt
    17161 tattcatagg atttgtttcc atgaagttac ttgctgattg gtgtgggaaa caaactgaaa
    17221 aaaaataatg taatgtatgg agggattacc tatgtggttt ctggcagttg taattataat
    17281 gttaataata tatttggtat atgcgcttat taatcctgaa aaattttaaa cagtataagg
    17341 ctaataagta agttgaattg gggggaacaa tttttatggt gcagatagta atagtgttag
    17401 cgatttttat gattttagta atacctatgg gcaagtattt atatcatata gctactaatc
    17461 aaaaaacatt tggagataga ctatttgata aagtggacaa ttttatatat aaggtatgta
    17521 gtatagataa gaaaaaagaa atgaactgga aacagtatgc attagcttta ttatttacaa
    17581 atgcagttat ggtatttata ggatatatca tacttagaac tcaaagtatg catattttta
    17641 atccaagtgg aattaaaagt atggaacaag gactatcatt taatacaata ataagtttta
    17701 tgacaaatac aaatcttcaa cattattcag gtgaatcagg actttcatac tttagtcaga
    17761 tgacagtgat aatatatatg atgtttacat cagctgcaac aggatatgcg gctgctatgg
    17821 catttgtaag aggtctagtc ggtaaaaaga aaacattggg aaatttttat gtagatttaa
    17881 ttaggataac aacaagagta cttttaccag gagctttaat tattgggctt atattagtta
    17941 cacaaggagt accacaaact tttgctggga cagaaacagt gactactata gaaggaaagc
    18001 ttcaagatat agctagaggt cctgtggcag ctcttgaatc aataaaacat ttaggaacaa
    18061 atggtggtgg attctttggt tcaaattcat cacacccatt tgaaaatcca acaataatat
    18121 caaatatagt agaaatatta tctatgatga tattaccagg agcttgtgtt gttgcatttg
    18181 gtcacatgat aaagaataaa aaacaaggtt gggttgtgtt tggcgcaatg tcaatcatat
    18241 ttttaatagg tctagtagtg tgctttaaag cagaaagtgc aggaaatcct attttatcac
    18301 aattagggct taatcaaagt atgggaagta tggaaggtaa ggaagttaga tttggtatag
    18361 cacaatcatc attattcaca acagtgacta cttcctttac gacaggtaca gttaataata
    18421 tgcatgatac actgactcct ttaggaggat tagtaccact tttaaatatg atgctaaatg
    18481 tagtatttgg tggtaaaggc gtaggtctga tgaatatgtt gatgtacgct ataatagcag
    18541 tattcttatg tggattaatg gtaggaagaa caccagagtt tttaactaag aaaatcgaag
    18601 gaaaagaaat gaagcttatt gctttactta ttatattaca tccactttta atactaatgt
    18661 tctctggtct ttcagtagca ataccagcag gacttgaagg aatttcaaat cctggattcc
    18721 atggattatc acaggtattg tatgagtttg catcttcagc agccaataat ggttcaggat
    18781 ttgaaggtct aggagataac actatgtttt ggaatataac aacaggtata gttatgttct
    18841 ttggaagata tgtgtctatt atagtactac tagcaatatc aagtttgtta gcatctaaaa
    18901 aagctgtaaa tgaaagtata ggaacactta gaacggataa ttttacattt acaatagttt
    18961 tagtacttgt tgttttaatt gttggtgctt taacattttt cccagcctta gcgcttggac
    19021 ctatttcgga gcatctagtg ttgtggcact aaaaaattgg gagggagtaa agttttatgg
    19081 aaactaaaaa aacaaagttt attacaaaag atattttcaa aacttccatt atagaagctt
    19141 ttaaaaaatt aaatcctaaa tatatgatga aaaatccagt tatgtttgtt gtagaaattg
    19201 gatttatagt aacattgata cttacaatag tacctagttt gtttggtgat gaaggcaata
    19261 acttaagagc ttataatggg attgtaacaa taatcttatt tataacagtc ctttttgcaa
    19321 attttgctga agctgtagct gaaggaagag gtaaagctca agcagataca cttaagaaaa
    19381 ctagaaaaga tacagtagca agggttatag atacgttagg aaatgaaaaa atgataagtg
    19441 caagtgagct aaaacttggt gatattgttt tagtaaatgc tggagaagtt atcccaaatg
    19501 atggagaagt tatagagggt atagcttctg tggatgagtc agcaataact ggagaatctg
    19561 cacctgtcat gagagaatca ggtggagatt tcgcatctgt tacaggtggt actacagttg
    19621 taagtgactg gttaaagata agaataacaa caaaaccagg agaatcgttc ttagataaaa
    19681 tgatagctct tgtagaaggt gcttcaagac aaaaaacgcc aaatgagatt gctttaaata
    19741 ctttgttagt agggttaaca cttatattta tggttgtttt aatatctctt tatccaatgg
    19801 caaactatgc aggtgtaaag attccaattt ctactatgat agctctcttg gtatgtttaa
    19861 taccaactac tataggtgga ttgttgtcag ctattggtat tgcaggtatg gatagagtaa
    19921 ctagatttaa tgtaattgca atgtcaggaa aagcagtaga agcttgtgga gacgttgata
    19981 ctatgatttt ggataagaca ggtacgatta cttatgggaa tagacttgca tcagaattta
    20041 tagcagttgg aaatgcagat tcaaaagatt taataaatta ttctgttatg tgttcattaa
    20101 aagatgatac accagaagga aaatctatag ttgatttagg tatgaaatta ggttcaacag
    20161 gtaagacaaa agaggcagag gaagctgagt ttgtagaatt ttctgcacaa actagaatga
    20221 gtggtattaa cttagctgat ggtagagcta taagaaaagg tgcttatgat agcataataa
    20281 aaagagtaaa agaatctggt ggtacagtgc cagaagattt agaagaaaat gtaaatcgag
    20341 tagctaaact aggagggaca cctttagtag tgtgtgtaga taatgagata tatggaatta
    20401 tctacttaaa agatacagta aaatcagggc ttgtagaaag atttgctaga cttcgagaga
    20461 taggaataaa gacaataatg tgtacagggg ataatccctt gacagcagct acaattgcaa
    20521 gagaagctgg agtagatgga tttattgcag aatgtaaacc agaagataaa atagatgcaa
    20581 taaaaaaaga acaattagag ggtaaaatag ttgcaatgac aggtgatgga acaaatgatg
    20641 ctcctgcact tgctcaggca gatgtaggtc ttgcaatgaa tagtggtaca acatctgcaa
    20701 aagaagcagc aaatatggtg gatttagatt cagacccaac taagatattg gaagttgttg
    20761 aaataggaaa acagctttta ataactcgtg gggctttgac aacatttagt atagcaaatg
    20821 atgttgcaaa atattttgcg attataccag ctatatttac tcttgcaata cctcaaatgg
    20881 agatattaaa tgtaatgaaa ctttctacgt catttagtgc gatattatca gctttaatat
    20941 ttaatgctat aattatccca tgtttaatac ctcttgcaat gaagggagta aaatatagac
    21001 ctatgaaatc acaagctatg ttaatgagaa atatgcttat atttggtctt ggtggagtta
    21061 tagtaccatt tttaggaata aaattaattg atttattgat tacaccttta gtaatggttc
    21121 ttaatttagg ttaataaatg gaggatataa aaatgaaaac attaaagcca gcattacttg
    21181 taagtattgt attgttagtt gtttgtggac ttgtatatcc acttgttttg acaggtgtaa
    21241 gccaagttgc atttaaagat aaagctaatg gaagtatgat agaagtaaat ggtgtaaaag
    21301 taggttcaga acttattggt caaagcttta cagatgcgag attctttaag ggaagagtat
    21361 catcagtaaa ctataatact tatacaaaag aagatttagt accagataaa gatggaaaca
    21421 catcttatgg aggtgtatca tcagggtctt ttaattatgg agctacaaat ccagaacttc
    21481 atgatagagt acaaaaagat atagaacagt ttttaaagga taatccaact gtcaaaagag
    21541 aggatatacc aacagattta cttacagcat caggttcagg acttgaccct aatataagtc
    21601 cagcctctgc aaaaattcag ataccagcta tagcaaaagc gtctggaata tcagaaagta
    21661 aattacaaaa aattgtagaa gataatactt ccaaaaaact ttttggagtt ttaggtgaag
    21721 atagagttaa tgtattaaag gttaatgtag aggtcgcaaa aatattaggt cttatatagt
    21781 attttgtgga attttagcaa caaaatatta ctcaagattt aatttaaagg ttaaatttta
    21841 aagagtgaaa atcgataatg attttcactt ttttatttga atattactaa tatttggaat
    21901 aaagtgattg taagtataaa atccaaaaaa aggttgcatt atcaaaatga taatactata
    21961 atatatttat cgttatcaat ttgataatag atttggacat ataggaggaa atagtatgtt
    22021 atataataac gcattagagt tgataggaaa cacacctgta gtaaggctga ataatttagg
    22081 ctgtactaat gggtgttcta acatatatgt aaaattagaa aaagtaaatc cagcaggaag
    22141 tataaaagat agagctgttt atgaaatgtt agagggttta gagcaaagag gagaattaaa
    22201 aaagggagat gtactagttg aagcaactag tggaaatact ggtattgcat tatctatgat
    22261 aggaaaatta aaaggatatg aagtagtaat cgtaatgccc gaaacaatga gcgttgagag
    22321 aagagattta atgaaggctt atggagcaaa tttggtgctt acagatggta aagctggaat
    22381 ggcaggttcc atagaaaaag caaatgaact tttaaaagaa aatccaaact ataaaagctt
    22441 aaaacaattt gaaaataaag ataatccaaa tgcacattat aaaacaacag cagttgaaat
    22501 tatgaatgat gtcaaagatt tagatatatt cgtatgtgga gttggaacag gtggtacttt
    22561 aataggaact gcaagatatt taaaagaaca aaatccaaat ataagagtaa ttgcacttga
    22621 accaaaaaaa tctccagcta tatcagaaaa caagactgga cctcataaaa tacaaggaat
    22681 aggtgctaac tttgttcctg aaaattatga ttctagtgta gttgatgaag taatattagt
    22741 agatgatgaa gatgcatttg atacagttaa attacttgca gcaaaagagg gaattttagt
    22801 agggatatct tctggagcaa atatatttgg tgctatagag atggcaaaaa agtatccaga
    22861 taaaaagata gttacagtag ctccagatgg agttgataag tatatgtcta tgggaatatt
    22921 ttaataattt tatttgaggg agtgaatact ttgtttaaga aaataaataa agatattgaa
    22981 tatataatga agaatgatcc agcagctagg tctaagatag aagttttttt actttatcca
    23041 tcagttcatg caatgataat gcataggatg gctcatgctc tttataagaa gaagaagctt
    23101 tttacagcaa gattaatatc ccagatatcc agatttatga ctggcataga aatacatcct
    23161 ggtgctaaaa tgggggaagg tatattgata gaccatggaa tgggtgttgt aattggagag
    23221 acagctgaag taggtaatag ggtgacaata tatcaaggag ctactttagg agctacagga
    23281 aaagatactg gaaagagaca tccaactgtt ggtgatgatg tattaattgg tgctggaaca
    23341 aaaatactag gacctttaaa tataggttca aattcaaaaa ttggtgcaaa ttctgttgtc
    23401 gttaaggatg tacctaatgg tgcaacagtt gttggtatac cagcaaaaat agtaaaaata
    23461 agaaacctag aacctgtaaa aaagaataaa aaagaagtgt cctatgagta tgatgaatta
    23521 gataatgtat attatatata ggatttatat aactataaaa taaactttat aaaaattatt
    23581 ttaaaaggta tttttttcaa atttgaggac ataataaaaa agaactgaat gttacagttt
    23641 tggttcatca atctttgata aacaagattt taaatttgta gcgtctagga ggattttatt
    23701 atgaaagcaa atgttaatca agatacttgt ataggttgtg gattatgtcc atcaatatgt
    23761 ccagaagtat ttgatatgaa ggatgatggg aaatcacatg ttatagttga tgaagtacca
    23821 agtgatgctg aagaatcagc agcagaagct agagaaagct gtccagttga tgcaatagat
    23881 gtgcattaat aaaataaatg cctataaaaa ttgaattttc aatttttata ggcatttgtc
    23941 ttttattcag ttagtatttc aacacctgtt tctgtaacta aaaccataca ttcccattga
    24001 gcagataatt taccatcttt tgtataaata gtccaattat tttcttcatc aacaaaaatt
    24061 tcgtgagttc cttcatttac cataggttct attgtgaata tcatcccagg aaccaatagc
    24121 atctcagtcc cttttttaga tacataactt acaaaagggt cttcatgaaa gcttaatcca
    24181 actccatgac cacctatttc tctaacaaca gagtatccat ttttctttgc ataagagttg
    24241 ataacatcac ctatatctcc taagaatccc catggtttgg caacttcaag acctttttgg
    24301 acacattcct ttgtaacttg aactaatttt tttgcatttt cgttaacatt acctatcata
    24361 aacattcttg aagcatctga atagtatccg ttaaaaatag tagaaacatc tacatttata
    24421 atatctccat cttttaagat aatgtcttta cttggaatac catgacaaac ttcattattt
    24481 actgatgtac atacactttt aggaaatcca ttatagtcta gtggagcagg gatagctcca
    24541 ttttgtagtg taaagtcatg aaccaactta tttatatctt ctgtagacat tccaatttcg
    24601 attttatctg aaatataatc caaaattttt gtgtttatta cagcactttt ttttatttcc
    24661 tcaatttgac tttcattttt tataatatca tgagttggta caatatgacc taacttagca
    24721 aatgaatcta ttttattatc catatccata tgacattttt tatatttttt agtacttcca
    24781 caccaacagc tatcatttct atttaacttc ataacttttc atccttcttt tattatttat
    24841 ttaaattatg ggttacataa actattttaa aacataacca ttataaatat tataacataa
    24901 atactaagaa atcctttata gatagtgatt tattcaaagt ataaattatt atatggttat
    24961 tgttgatgaa aagaggatag ttaaatgtat tattggatat tagcgcactt aatagtttag
    25021 ttcaagtttt tcaagaaaat catatgttag aggacaattt tcctttaaag tattttttga
    25081 atcttcatca agataataat gtacaaatga ttctgcaaaa aattcttcta taaacttgct
    25141 tatatatgca tgtgcaactt gcttagggtc ataaagctta tatctttcct gagcaaatac
    25201 ttccataaat tcttcagaat ttgatttttt atttaaaaca tttttatcta tagcatgtgc
    25261 agtttcatgt aattctaaat tttttgatga atgtacattt gcatagctag ggttactata
    25321 acctatttta gccactatag aattatttct atatatacca ggtacatctt tccaagtctt
    25381 gcctgatctt acccaacatg gaggtaattg atattttaaa tcactaaatt ctggttcatc
    25441 agttagattt gaatttatta attttatttt tatatccttt tctttaagtg tctgtaaata
    25501 tttaatattt atttttgcaa gtctgttttt catattttca acttcatctt tatcataatt
    25561 caagtcatca ggaagtataa gcatttgttc aattatatct atactactgt cttttatatt
    25621 ttcagattct tcatcaaatt tatattgaag agtattattt tcatagatag ttatatttgt
    25681 attattttct atagaataag agtgaatatc ctctaaatct aaaatattca tttgttgtaa
    25741 aatatgtttt gtttcgccac tccacactac taaagaaagt gaattaaaat taattagtgg
    25801 attttctttt gcttttatat cattgcttat atctacatca aatacatatt caattgagtc
    25861 ttctatgtta agactatctg tattcttttt aatatataaa tacgcttgtt ttaagtctat
    25921 ataaatctca tctaaagatt cgtcataaaa ttctgataaa ttattagtaa agagttcttc
    25981 acttaaaagt tcatttttat cagttatact ttcaattaaa atattaattt cttttatcat
    26041 attgtaaata cttatttttc tatttgcttt ttcactagat acattgcatg gcgcaagagc
    26101 aatgcaataa aaatcttttt cttttttata aaaggcttta agtgattttg ataaaagtgt
    26161 aaagtctaca cctatctgta agttgacctt aagtgagtca ttttgtaata attcagtatt
    26221 atttctttta gctgtattta aattgttttc cataatcatt gccccctttt tattagggta
    26281 tcataatttt tttatatgtg tcaatttgtt tttttgaaaa ttataatttt tttgaaaatt
    26341 ttatttttta taatttgtga attttttatt atagaaataa atatgtta
//
LOCUS       DAJMZY010000051        25889 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.051, whole genome shotgun sequence.
ACCESSION   DAJMZY010000051 DAJMZY010000000
VERSION     DAJMZY010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 25889)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25889)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25889
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.051"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            9..776
                     /gene="larE"
                     /locus_tag="OE968_002073"
     CDS             9..776
                     /gene="larE"
                     /locus_tag="OE968_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015617102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent sacrificial sulfur transferase
                     LarE"
                     /protein_id="HCP7219352.1"
                     /translation="MLLELGSVVVAYSGGVDSNFLLKVAKDTLGENVIAVTIHAMMHS
                     SREIEEAKQYTQNFGVKHIILNIENFDLKEFKENGVDRCYHCKKYIFSKIKEVAKEHN
                     IKYIVDGTNIDDLGDYRPGLKALSELGVISPLKDSSLKKEEIRSLSKTLGLNTFNKPS
                     FACLASRIPYGVEITDENLRIVEKSEEYLSNLGFSQFRVRMHGDIARIEVGQEELGKF
                     FENNNFNKVDTKLKIFGFKYVTLDMSGYKMGSMNLNV"
     gene            831..1979
                     /locus_tag="OE968_002074"
     CDS             831..1979
                     /locus_tag="OE968_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HCP7219353.1"
                     /translation="MKNYTLISPCFFGMEKMLAREITNLGYEIIKTEDGRITYKTDEF
                     GIAKSNMWLRCAERVHLKIAEFEAKSFDELFENTKRINWSRYIPYGAQFPISKASSIK
                     SKLYSTPDVQAIVKKAIVESLKKSYLEDGLLKEDKEKYPIFVFIHKDKVTISIDTTGD
                     ALHKRGYREKANKAPIRETLAAGLIYLTPWKAGRVLVDPMCGSGTILIEAAMIGINMA
                     PGLNREFISEKWRTLDKKIWWDVRKDAFNKIDNESKFKIYGYDIDEESIDIARENAEI
                     AGVDEYIEFNVGDATQFKSEDEFGFIITNPPYGERLEDKDSVKQLYKELGYAFRKLKN
                     WSYYLITSYEDFEYEFGQKADKKRKLYNGMLKTNFFQYPGPKPPRNNK"
     gene            2115..3503
                     /locus_tag="OE968_002075"
     CDS             2115..3503
                     /locus_tag="OE968_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HCP7219354.1"
                     /translation="MKVLKLITVVALMMLFVTGCNIKTESPEQLAKIPDYDDTKKVLY
                     DGIDQLLKPDSSMILPSNTKEVGKINKVDLNSDGIDELVVFEQKEDLSNNVSQVGFVT
                     LSYNGEKYVLGDHFLENGESIEYANFYDLDSDGYKEVILLVKSKDKTNMHIYKVVDNE
                     ITKIYDLDASWLQNKEDFNDMKVKIGYIDGDDKLDILMLHLNNKTNEMFASVANFDGK
                     MKIKDSVKFENVKNLSELYITLGNVASSVGNSSAAIKGIVLDIPILKDNNYITQILYM
                     KDGKINKAFSDYDKTITKSYYIPVDDIDKDKIIEIPIVAGSTGNNKNTYSSKSSATIS
                     WYRWNGKEGADSSLIFTSQIYYNYKYNFKLFIPNNLFDKILVEQEFVGEKAVFKFYYF
                     DYSDRKNLFNIVVESKNKLEDRKNTGTQNSIVLQESDEYTFLLVVNNANEMDKLDMTI
                     DALKEYFSLIYG"
     gene            3532..4230
                     /locus_tag="OE968_002076"
     CDS             3532..4230
                     /locus_tag="OE968_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCP7219355.1"
                     /translation="MKEKILILEDEIGIRSFVSINLKREGYEIVEAGTGREAIEKMTT
                     EKDITIALLDVMLPDISGIEVCKFIRENFDQVGIIMLTAKAQEDDKIEGFISGADDYI
                     IKPFSIKELLVRVSALLRRVAKDDSSVKSSEIVSPPFILDIDKRKLFKNGKEIELTPT
                     EFSIVKYLISNAKQSLSRDQILDEVWGTNYLYDFKIVDVNIRRIRNKIEDDPSKPKYI
                     QTIWGYGYCFRKEE"
     gene            4233..5666
                     /locus_tag="OE968_002077"
     CDS             4233..5666
                     /locus_tag="OE968_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HCP7219356.1"
                     /translation="MLHFEGLRKKVIKNYFIIIIIMVTLFEGLFMFYIQNYYYDSVKQ
                     LLESEIKYADEYNAITMETTSFEKKVKNIFDKQPLTKNSEFGISIIDKDKNIILDQYG
                     FKSKEKANYEDVNNALKDIKTKNLTPYTYRIPDTGEHVMSISLPLKVNNIIEGVVRYT
                     VSLDAIDNAILKQATWLILAGIFILIIAILISLKFAETLIKPLRELKKFANELAVGNY
                     NIKLEKMKIVDDEIGDLAQTFEHMAHEIDKSEKLKEEFISSVSHELRTPLTSIKGWSE
                     TLGYESITREELDLGLGIIQDETERLIKLVEELLDFSRLSSDRIKLHVDIVDVEGLIV
                     GVVNQLKVKAAEKDISLLFEFENEFIENIQGDKNRLRQVLINLIQNSFKFTSQGGYIK
                     VVASQDEEITTISVEDNGSGIEKQNLNKVLDKFFQEDYNKAGSGLGLAISNEIVKLHG
                     GRMKIESEKNVGTKITFNIKNKFAKQA"
     gene            5688..6425
                     /gene="truA"
                     /locus_tag="OE968_002078"
     CDS             5688..6425
                     /gene="truA"
                     /locus_tag="OE968_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011010156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HCP7219357.1"
                     /translation="MRNIKMIVAYDGSRYKGYQKLGDNNMTIQEKLENVLSKMTNETV
                     EIIGSGRTDMGAHARGQVVNFRTNCMDSLDKIQKYLYEYLPEDIVVKTVEEVDERFHS
                     RYNVKSKTYMYKIDNNKYHNPFIRKYATHVSKKLDLDRMRKASEYLVGEHDFTSFASS
                     KSKKKSNVREIYSINIKEDDNVIEIYVEGNGFLYNMVRIIVGALIDVGLKRRAPQDIK
                     YMLESKDRCQSSDTAPAKGLCLWKVTY"
     misc_binding    6536..6743
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            6996..8195
                     /locus_tag="OE968_002079"
     CDS             6996..8195
                     /locus_tag="OE968_002079"
                     /EC_number="6.3.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
                     /protein_id="HCP7219358.1"
                     /translation="MKEKVVLAYSGGLDTSIIIPWLKENYEDIDVIAVCGNVGQEDKM
                     EDVYEKALQSGASKAYVDDISEEFVTETIFKAVKAEAKYEGKYLLGTSLARPIIAKKL
                     VEVAHKEGAKYICHGCTGKGNDQVRFEATIAALDPTIKVIAPWRIWDIKSREDAIDYA
                     EKHNIKVTATKAKIYSVDANLWHVSTEGGDIEHLENEHKKDVYKQCVDPEDACDVAEY
                     VEVYFEKGVPKKVNGEELSPVALIHKLNELGCKHGIGVIDIVENRLVGMKSRGIYETP
                     GGTILYEAHNILESATLDKDTLHFKQMVSYKYGELIYNGLWYCKLRESIDAFMEQTQD
                     NVTGTVKVKLYKGNIKPAGIFTENALYDEGISSFGNSELYDHKDAEGFINLFTLPLKI
                     RAMKAGK"
     gene            8442..9488
                     /locus_tag="OE968_002080"
     CDS             8442..9488
                     /locus_tag="OE968_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4872 domain-containing protein"
                     /protein_id="HCP7219359.1"
                     /translation="MRKIIEIKHHSHDYECMWNGIEDLYINKTGEYLPNDFFFLLSGF
                     GSFCYMKTNKADLKRMVALGDGRTKQMYKFLAPIVGFEYKHHEFKKYEQALKKAKSEI
                     DDGYPVILGALDMYYLPYYKKLYHKEHIPFHYILMVGYDDEGIYLYDCGRTELLHLSY
                     DKLRESMNCNSPGLSKENTICTIRMNTSKNKYNIAREAIAIKRDMFLNPPKGFLGYKG
                     FEKFIKELPQWNTELDKDDYDKILTNMVMFFGTVPTIPNAIKGIKEPDTVQFKGGFDK
                     MSRMLNSIGEEYKNNSFIQVADIFDKTAIIIEKISNIIIDYLTQTCDDTEQLPLLFSE
                     VLEHMKTGYLILDV"
     gene            9596..10759
                     /locus_tag="OE968_002081"
     CDS             9596..10759
                     /locus_tag="OE968_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HCP7219360.1"
                     /translation="MRTVKQVSDLTGISVRALHYYDEIGLLKPNKITDAGYRLYDDES
                     IKTLQQILFFKEIDIPLREVKEIMSSQYFDKVEALKNQKKLLILKRKRLDELIELINQ
                     TLRGEGNIDFKEFDMSEYFNVLEEFKREHRNKVIKIYGSVEKYNEYIERVKSNEEKIA
                     KMAIKQYGTIEKFAKAIKTNFSSDILNLGEKFDRYKNDCLKEKHPKLKELYRKLVEDL
                     SRNPSSTDLQEIAKAITDISKKDYEIFSMDTGDDNWYYMVQNYLVNPMWIEEVDKKYG
                     SGAGKFIGQVLKTYLRDRKPKINTLYEKLVEDLSRDCSSREVQSIVEEIDNEMKRSNE
                     FYKIDNGERYFDYMSELYLQDSNYIKVTDKNYGDGASKFIGEAFKIYFDNNNC"
     gene            complement(10848..11228)
                     /locus_tag="OE968_002082"
     CDS             complement(10848..11228)
                     /locus_tag="OE968_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4363 family protein"
                     /protein_id="HCP7219361.1"
                     /translation="MKSTTFVILWTILFVLFGFYVNNKLYDFTEGYKDNISVLEKSIE
                     NEDWEKAQKEADSISTSWNKEKNHWYKVLNHEYFDEIGLRFNILDKAIYTENKLKSLE
                     EVESIKTYLGNIIESVKFDVNYIF"
     gene            complement(11231..11890)
                     /locus_tag="OE968_002083"
     CDS             complement(11231..11890)
                     /locus_tag="OE968_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HCP7219362.1"
                     /translation="MTVVLIRSIILYITVLIALRVMGKGEIAEMNCFDLVITLLIAEV
                     ASVPMENNNIPIINGVAAISGLVIMQTLISFLSLKSRKLSSFLSGKPSVLIDKGKIVY
                     KELKKERISIDELLEQLRIQGYFNLKDVQYAILETDGNLSVVPASSYNSTPPRAFNHL
                     PIPLILDGRIINKNLDIAQKDTNWLMGILKSNHIETFKDVLICVLDENDKIFIQNKKG
                     D"
     gene            complement(11996..12970)
                     /locus_tag="OE968_002084"
     CDS             complement(11996..12970)
                     /locus_tag="OE968_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease domain-containing protein"
                     /protein_id="HCP7219363.1"
                     /translation="MKYKLFIDFEFNILDDNKNKPKEYNGAELISIGGVLVDNEFNTI
                     DNYYSLVKPKYNKILSNKCKNLTKLNQLDINNAPNLLYVMDDFYKWFCKFDDVTIYNW
                     GDFDITGLLTSFRVYKYTGKCLELFNMMIDIQPFISQHITYNNRILSKQISLLNMKKI
                     FSVEGDIKHNSLSDAVDLMNVCKCFFFNSPKNIDILEELYNKLPALKTPLYYIPYFED
                     ENFELKFDRTPEDIIIYLKQILTILNISKKEIYFKKRSVLVNNSKIINFKNLSSSFKL
                     IKLNEFEEYPDFILKLGDKKSFVESVIKINKSNRKSIKNLILKLSKKP"
     gene            complement(13010..13357)
                     /locus_tag="OE968_002085"
     CDS             complement(13010..13357)
                     /locus_tag="OE968_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219364.1"
                     /translation="MLNLKEIREEIIKKYIGDSLISELTEELKNILITDLQSNPFKSN
                     IELSIIPANIEIFKKIENILIDSKVNLKMGWERILINYILKDLFELNYEINKSCNEPL
                     MFRVIISIDSYDA"
     gene            complement(13575..14531)
                     /locus_tag="OE968_002086"
     CDS             complement(13575..14531)
                     /locus_tag="OE968_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HCP7219365.1"
                     /translation="MKKILITGALGQIGSELTIKLRNEYGEQNVIASSRRVKEGNPVC
                     ESGIFEILDVTDKNRFFEIAKKYDVDTIIHLASLLSAVAESKPLEAWNLNMNGLINGL
                     EIAKELDCKFFTPSSIAAFGENSPKNMTPQDTLQRPNTMYGVTKVSGELLCDYYHSKF
                     GVDTRGVRFPGLISYVTPPGGGTTDYAVDIYYEALKNKRYKSYIAEGTKMDMMYMPDA
                     LQSIVDLIEAPADKLIHRNAFNITAMSFSPEEIADSIKKYIPDFVIEYDVDPVRQSIA
                     DSWPNSLDSSSAVKEWNFKFSYDLDKMTKDMLEKLSEKGIGK"
     gene            14974..15342
                     /locus_tag="OE968_002087"
     CDS             14974..15342
                     /locus_tag="OE968_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C-GCAxxG-C-C family protein"
                     /protein_id="HCP7219366.1"
                     /translation="MTRPSIYHSQGYTCAEALIKSYNEEHNTDIPISIGSGMGVGMNV
                     GSVCGAVNAAVVIIGYLNGRNSNLDENIARKYSRELLNRVRNKYSSEICVSLKKNKVT
                     CEEIINFTYDALNDMLKNQK"
     gene            15767..16012
                     /locus_tag="OE968_002088"
     CDS             15767..16012
                     /locus_tag="OE968_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219367.1"
                     /translation="MFIDEELEGYILTCKISEDFKNIPEYSDEEFYVTVYKDESSDSG
                     YYALLENKEERVVWDGEVVANNIFNNLWIVINKVKTG"
     gene            16111..16374
                     /locus_tag="OE968_002089"
     CDS             16111..16374
                     /locus_tag="OE968_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1883 domain-containing protein"
                     /protein_id="HCP7219368.1"
                     /translation="MEYSYSKMNLKKGDIVEVNLEKQANVILLDHINYVKFKNQRNYD
                     YYGGFAKKNPCRMRVPNTGTWYLVVNQDGNSGIVNFSINTIQN"
     gene            complement(16659..17606)
                     /locus_tag="OE968_002090"
     CDS             complement(16659..17606)
                     /locus_tag="OE968_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013378669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(4Fe-4S)-binding protein"
                     /protein_id="HCP7219369.1"
                     /translation="MSNVTAEQKKEVKGRGFLPSRDGEHFAARIITVNGVINASQAKK
                     IAEAAEKFGNGQLAFTTRLTVELPGVKFEDIEALSEFIASENLITGGTGSRVRPVVAC
                     KGTVCVHGLADTQALAAEIHEEFYKNWYDVKLPHKFKIGVGGCPNNCIKPDLNDLGIV
                     GQRVPDYDSELCVGCKKCAVVEVCPVKAAKLTDKGKLEIDSNLCNNCGKCIESCNFDS
                     IEEKESGYKVYIGGKWGKSVRPGTQIDRLFSKEELMTLIEKAILLFREQGNTGERFGI
                     TIDRIGADKFIEMLLSDEVLERKEEILEALLHLTGGAVC"
     gene            complement(17609..19240)
                     /locus_tag="OE968_002091"
     CDS             complement(17609..19240)
                     /locus_tag="OE968_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HCP7219370.1"
                     /translation="MKVLIIGGVAAGTKTAAKIKREMGDNCSVTILNKGDDISYAGCG
                     LPYYVGKIIEDKSSLIVNTPESFSKLTGAEVRCGVEVTSIDRNAKQVTLKTLSTGEKE
                     NLSYDKLVIATGADPIKPPIPGIDLPGVFFVRTPNDAIKLRDSIENGIKRAVVIGGGF
                     IGLEIAENLSAMGIRVSVVDMAEHVMPGFDTDFAEYVENHMADKGIMIFTGDQVVGIE
                     GENKVEKLRTKNRAIKTDLVVMSVGIRPNTGFLKDTGLEFAPNNTIIADEYMLTNDKD
                     IYVVGDCAFVKNSLTNKPTWSPMGSSANHEGRICAQNISGKSKTYNGVLGTTVVKLPE
                     LNAGKTGLSKEIAEKEGYNVCSVTIATDDKAHYYPGASNFIIRMVAEKNTRKLLGVQV
                     MGPGAVDKIVDIAATAITLGADLYSLESMDLAYAPPFSTAIHPFVVAVNVLQNKLNGE
                     LDSVLLDEIEDFDSWTKLDVSKAPSIPSLRYIPVGEINGEIEGLAKDEKILLICAKGK
                     NSYMAQNRLRRFGYTNTKVLEGGILFYPNLKVMEE"
     gene            19370..20287
                     /locus_tag="OE968_002092"
     CDS             19370..20287
                     /locus_tag="OE968_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCP7219371.1"
                     /translation="MTIRSLEIFVKVAECGKMSEVARNMYITQSSVSQAISEIEKEYG
                     VKLFDRISKKLYLTEAGKKLLGYGRHLLAVNEEMNDCMKHCAKNIRIRVGATVTVGTC
                     VISPIMLELYKVNPLIEPEVFVEDTRLIAKKLLNSELDIAIVEGKIKHPDIVTKSIIN
                     DNLVLICSHKHEFYKRDSIKVSELSNQPLIMRELGSGTRAQLEKQLKELKIPMNIRWS
                     CYNSEAILRAVVDNFGIAVISELLIEDYLKKHLLWACDIEGINLHRTFDIAYHRSKFF
                     TENISAFFDISVEYGKKQARKKSRSVNSL"
     gene            complement(20344..20925)
                     /locus_tag="OE968_002093"
     CDS             complement(20344..20925)
                     /locus_tag="OE968_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HCP7219372.1"
                     /translation="MGITLAKGQKVSLTKSNPGLKKVIVGLGWDINKYDGGFDFDLDA
                     SAFLTGTDGKVTNDGDFIFYNNLKHASGAVEYMGDNRTGVGDGDDEQINVDLSKIPQN
                     IAKISFSVTINEAITRRQNFGQVENSYIRIYNEETNEELIKYELGEDFSIETAIVVAE
                     LYRHNGEWKFNALGSGFEDGLAGLCKNFGVNIG"
     gene            complement(20965..21531)
                     /locus_tag="OE968_002094"
     CDS             complement(20965..21531)
                     /locus_tag="OE968_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HCP7219373.1"
                     /translation="MSVSLQKGQRVSLVKDNNPVKNLVVGLGWDMNKLGKKNYDLDAF
                     AIALTNQDKMNVRGDLVYFGNLKHPSKAIIHTGDNLTGKGEGDDEQIIVNLEDIPEYV
                     HKIVFGVSIYKAKKRDQDFGQMNNSFIRLIDSNSKQELFKYNLQEDFSGKVTVLAGEI
                     YRRNEEWKFNALGIGQNEELRELINTYK"
     gene            complement(21987..22847)
                     /locus_tag="OE968_002095"
     CDS             complement(21987..22847)
                     /locus_tag="OE968_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HCP7219374.1"
                     /translation="MLLKKDRITFSEILILIVGCILMAISLNLFFNPHAIAAGGITGL
                     GVVLNSLFGVELWIVNLLLNVPLFIFAYKILSKKDCFKTVLGIIFLTIALKLTANMAT
                     LDITNDMYLAIISGSILMGVGQGLIFRINGSTGGTDLMALLLNKYFPTFSIPVLMGIV
                     DCVVVVLSGIVNRQVEIALYSTVALYILVKVSDLLIEGFNYSKSFTIISDLSKDISKK
                     IMEDLDRGATILKGEGAYTGENKNVLLVVVEKKEVVELKKLVKNVDPNAFIIITDIHE
                     ALGNGFKKIE"
     gene            22996..23886
                     /locus_tag="OE968_002096"
     CDS             22996..23886
                     /locus_tag="OE968_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HCP7219375.1"
                     /translation="MAKLTLEHIKGNTYYIPLPTIVGVYVDGKDAILIDSGNNKDTAR
                     QVLRLLEEHNLNPKLIINTHSNADHIGGNAYLKNQTKCKIATTKIEGYFTENPILESA
                     FLYGGYPSKALKNKFLLAKESEVDYIIPSNGKIVDTELEAISLPGHYFEMIGVRTPDN
                     VLFVADSLTPENIITKYHFFFLLDIDSQFKTLEKLRMLEADFFVPSHSVKTTDIKSLI
                     NINKKKMEEIIDNIKKVCYEPVMIDEVIEKMCDLYNVKLDANQYVLVGSTIRSYITYL
                     YENNMVEYIFDGGKMMIKAA"
     gene            24104..25858
                     /locus_tag="OE968_002097"
     CDS             24104..25858
                     /locus_tag="OE968_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp23"
                     /protein_id="HCP7219376.1"
                     /translation="MYIMNKKFKKFSKKLSILILVLTMFLFNNLTANAQIKEDSIIGI
                     DRYETAGLIADRQTYDTVILVNGDKNLSDGLSSSGLAGAINAPILLTKKSEIPKATLN
                     RLDNKSLNVVKKVYIIGGYNTIENSVEKDIKRKGIQVERINGNNRIETSYNVAKKINE
                     VSSVKEVMLTNGFVGEADAMSIAPVVAKNKGAIILTDGKSVPFKTEGLNVYAIGGKSA
                     INEDLVNETKAIRIGGNDRFETNKKVMEKFYNGATDFYITNGYQLVDALTLSPLAKEK
                     PIVLVADGSNKGILKGAKSITKVGGIDANIYKQCLDMIKYNNMDMTPNILKHLTSVEG
                     NEVSEILIESDNLGVVVEKTNTNKFEFDYVSVTNEKNCTFSVYKENSSNNIKNGKLVV
                     SAKKKIDKKDSDLQDMNGDNMINANKDRMVNVIKIGVPDKMYSNFKVDVESGSVELYN
                     IKGGATVDVNDGIANIVDNNVTNPFNINTNSGISGVTAETISSEIKFRANNGIVNVTA
                     TNINGNISLFGSDNKDTFDGIFKLNLKKEPSNLHLKLIGNGINKLPEGWSKDYILGNG
                     QPIIEVKNNGINNISIGE"
BASE COUNT         9940 a         3092 c         4010 g         8847 t
ORIGIN      
        1 taaaaaaaat gttacttgaa ttaggcagtg ttgtagttgc ttattctggt ggagtagata
       61 gtaatttttt gcttaaggtc gcaaaagata cattaggtga aaatgttata gctgtgacta
      121 ttcatgcaat gatgcattca agtagggaaa ttgaagaggc taaacaatat actcaaaatt
      181 ttggtgttaa acatatcata ttaaatatag aaaactttga tttaaaagaa tttaaagaaa
      241 atggtgttga tagatgttat cattgtaaaa aatatatatt ctctaaaata aaagaggtag
      301 caaaagaaca taatataaag tacatagtag atggaacaaa tatagatgat ttaggagact
      361 atagacctgg gcttaaggca ttgagtgaat taggagtaat tagtccatta aaagatagta
      421 gtttaaaaaa agaagaaatt aggtcgcttt caaaaacatt aggattaaat acttttaata
      481 aaccatcatt tgcatgtctt gcgagtagga taccttatgg agttgaaata acagatgaaa
      541 atttaagaat agtagaaaag agtgaagaat atctatccaa tttaggtttt tctcaattta
      601 gagtgagaat gcatggagat atagctagaa tagaagttgg acaggaagag ctaggtaaat
      661 tttttgaaaa taacaatttt aataaagttg atactaaatt aaaaatattt ggctttaaat
      721 atgttacact agatatgtca ggatataaaa tgggaagcat gaatttaaat gtgtagatta
      781 ttttaaaaat aaataagttt tatagttaat ataaggaaac aggaggtttt atgaaaaatt
      841 atacgttaat atcgccatgt ttttttggaa tggaaaaaat gctggctaga gagattacta
      901 atttaggata tgaaataata aaaacagaag atggaagaat aacatataaa actgatgagt
      961 ttggaatagc aaagtcaaac atgtggttga gatgtgctga aagagtacat cttaaaattg
     1021 ctgaatttga ggcaaaaagc tttgatgaat tatttgaaaa tacaaaaaga ataaactggt
     1081 ctagatatat accttatgga gctcaatttc ctatatcaaa agcttcctct ataaaatcaa
     1141 aattatacag tacaccagat gtacaagcca tagtaaaaaa ggctatagta gaaagcttaa
     1201 agaaaagtta tttggaggat ggtttgctta aagaagataa ggagaaatac cctatttttg
     1261 tatttataca caaagataaa gtaaccattt ctatagatac aacaggagat gctttgcata
     1321 agagaggata tagagaaaag gcaaataaag ctccaataag agagacttta gctgctgggc
     1381 ttatttattt aactccctgg aaagcaggta gagttttagt agaccctatg tgtggttctg
     1441 gtactatatt gattgaagct gctatgattg gtataaatat ggcacctggc ttaaatagag
     1501 agtttatatc agaaaagtgg agaactcttg ataagaaaat atggtgggat gtaagaaaag
     1561 atgcttttaa taagatagat aatgaatcta aatttaagat ttatggatat gatatagatg
     1621 aagaatctat agatatagct agagaaaatg ctgaaatagc aggtgtagat gaatatatag
     1681 agtttaatgt aggagatgca actcaattta aaagtgaaga tgagtttgga tttataatca
     1741 ctaatcctcc ttacggagaa agattagaag ataaagacag tgttaaacag ttgtataagg
     1801 agcttggtta tgcatttaga aaattaaaaa attggtcgta ttatttgata acttcttatg
     1861 aagactttga atatgagttt gggcaaaaag cagataaaaa aagaaaattg tataatggta
     1921 tgttaaaaac taactttttc caatatccgg gtcctaagcc tcctagaaat aataaataag
     1981 ttttacatga tttatttgta aaatataaaa ttttattaaa ataagtaaaa cattatgatg
     2041 ccctgaaacg tctaattatt gtgaggagat ttttgtgaac aaatttaaag atttatagga
     2101 ttaggaggag ttaaatgaaa gtgttaaagc ttattactgt agtagccctg atgatgttat
     2161 ttgttactgg atgtaatata aaaactgaat ctccagaaca attagcgaag atacctgact
     2221 atgatgatac aaaaaaagta ttgtatgatg gtattgacca gttactaaaa ccagattcat
     2281 ctatgatatt gccttctaat acaaaagaag taggaaaaat aaataaggta gatttaaaca
     2341 gcgatggaat tgatgaatta gtagtatttg aacaaaaaga agatttaagt aataatgtga
     2401 gtcaggtagg gtttgtaacc ttgagttaca atggagaaaa atacgtactt ggagaccatt
     2461 ttttagaaaa tggcgaatca atagaatatg ctaattttta tgatttggac tcagatggat
     2521 ataaggaagt tatcttattg gttaaatcca aagacaaaac gaatatgcat atatataaag
     2581 tagtagataa tgaaataaca aaaatatatg acttggatgc atcatggctt caaaataaag
     2641 aagattttaa tgacatgaaa gtaaaaattg gatatataga tggagatgac aagttagaca
     2701 tattgatgct tcatttgaat aataagacta atgaaatgtt tgcaagtgtt gcaaattttg
     2761 atgggaaaat gaaaatcaaa gattctgtta agtttgaaaa tgtaaaaaac ttaagtgaat
     2821 tatatataac attaggtaat gttgcttcat ctgttggaaa ttcttctgca gctataaaag
     2881 gtattgtact tgatattcct atattgaaag ataataacta tattacgcag atactttata
     2941 tgaaagatgg gaaaattaac aaagctttta gtgattatga taaaactatt actaaatctt
     3001 attatatacc tgtagatgat attgacaaag ataagattat agaaatacct atagttgcag
     3061 gcagtacagg taataataaa aatacttata gttctaaatc atctgcaact ataagttggt
     3121 atagatggaa tggaaaagaa ggtgctgact caagtttaat atttacaagt cagatatatt
     3181 ataattataa atataatttt aaattattta ttccaaataa tttatttgat aaaatacttg
     3241 ttgaacagga atttgttgga gaaaaagcag tatttaaatt ttactatttt gactattcag
     3301 accgtaagaa tttatttaat atagtagtag agagtaaaaa taaacttgaa gatagaaaaa
     3361 atacaggtac tcaaaattct attgtacttc aagagagcga tgaatatact ttcttactag
     3421 ttgtaaacaa tgcaaatgaa atggataagc tagatatgac tatagacgca ttaaaagaat
     3481 atttctcatt aatatatggt taatattata ctcaattgga ggttttattt tatgaaggaa
     3541 aagatactta tactagaaga tgaaattggt attagaagtt ttgttagtat aaacttaaaa
     3601 agggaaggct atgaaatagt tgaggcaggt actggaagag aagctataga aaaaatgaca
     3661 acagaaaagg atattacaat agctctttta gatgtaatgc ttccagatat aagtggtata
     3721 gaagtatgta aatttataag ggagaatttt gaccaagtag gtataataat gcttactgct
     3781 aaagctcaag aagatgataa aatagaagga tttatctcag gagcagatga ttacatcata
     3841 aaaccattta gtataaaaga gcttttagtc agagtttctg ctcttcttag aagagtagca
     3901 aaggatgatt caagtgttaa gtcgagtgag atagtttctc caccatttat acttgatata
     3961 gacaaaagaa aattatttaa aaatggaaag gaaattgagc ttacaccaac tgaattttca
     4021 atagtgaaat atctaatatc aaatgctaag cagtcgttaa gtagagacca gatattagac
     4081 gaagtatggg gaactaacta tttatatgat tttaaaatag tagatgtaaa tataagaagg
     4141 ataagaaata aaatagaaga tgacccatca aaaccaaaat atatacaaac tatttggggt
     4201 tatggatact gttttagaaa ggaagaataa tagtgttaca ttttgaaggt ctgagaaaaa
     4261 aagtaataaa aaactatttt ataataatta ttataatggt tactctgttt gaaggattgt
     4321 tcatgtttta catacaaaac tactattatg attctgtcaa acagctactt gaatctgaaa
     4381 taaaatatgc tgatgaatat aatgctatta caatggaaac tacaagtttt gagaaaaaag
     4441 taaaaaatat atttgataaa caacccttaa ctaaaaattc agaatttgga atttcaataa
     4501 tagataaaga taaaaatatt atattagacc aatatggttt taaaagtaaa gaaaaagcaa
     4561 actatgaaga tgttaacaat gcattaaaag atataaaaac taaaaattta acaccttata
     4621 cttatagaat accagataca ggggagcatg ttatgagtat ctccttacca cttaaggtaa
     4681 ataatataat agaaggtgtt gttagatata cagtatcatt agatgctatt gataatgcaa
     4741 tattaaagca agctacatgg cttatattag caggaatatt tatacttatt atagctatac
     4801 taataagtct taaatttgct gagactctta taaaaccatt acgagagcta aagaaatttg
     4861 caaatgaatt ggctgtagga aattataata taaaattaga aaagatgaag attgtagatg
     4921 atgaaattgg tgatttagca cagacatttg aacacatggc acatgagatt gacaaaagtg
     4981 aaaaattaaa agaggaattt atatcatctg tatctcatga actaaggact cctcttacat
     5041 ctataaaggg gtggagtgaa accttaggtt atgaaagtat aacaagagaa gaactagact
     5101 taggtttagg cattatacaa gatgaaacag aaagacttat aaaactagtt gaagaattat
     5161 tagacttttc aaggctttct tcagacagga taaaacttca tgttgatata gttgatgttg
     5221 aaggtttaat tgtaggtgtt gtaaatcaac ttaaagttaa agcagctgaa aaagatatat
     5281 cacttttatt tgaatttgaa aatgaattta tagagaacat tcaaggagat aaaaatagat
     5341 taagacaggt tctcataaat ttaatacaaa attcatttaa atttacgagt caaggtggtt
     5401 acataaaagt tgtagcttct caagatgaag agataacaac catatcagta gaggataatg
     5461 gttcaggtat agaaaagcaa aatttaaata aagtgttaga taaatttttc caagaagatt
     5521 ataataaggc tggtagtgga ttaggactag caattagtaa tgaaattgta aaacttcatg
     5581 gtggaagaat gaaaatagaa agtgaaaaga atgttggaac aaaaataact tttaatataa
     5641 aaaataaatt tgctaaacaa gcataaattc ttagaaagag gattaagatg agaaacataa
     5701 aaatgatagt agcatacgat ggttcaagat ataaaggata tcaaaaatta ggtgacaata
     5761 atatgactat tcaagaaaaa cttgaaaatg ttttaagtaa aatgactaat gaaacagtgg
     5821 agataatagg ttctggaaga actgatatgg gagctcatgc aagaggacaa gtggtaaatt
     5881 ttagaactaa ttgtatggat tctttggata aaattcaaaa atatttatat gaatatttac
     5941 cagaagatat agttgtaaaa actgttgaag aagttgatga aagatttcat tcaagataca
     6001 atgtaaaatc aaagacttat atgtataaaa ttgacaataa taagtatcat aatcctttta
     6061 taagaaaata tgctactcat gtaagtaaaa aattagattt agatagaatg agaaaagcaa
     6121 gtgagtattt agtaggagaa catgatttta ctagttttgc ttcttctaaa tctaagaaaa
     6181 aatcaaatgt aagagaaatt tattctataa atataaaaga agatgataat gttatagaaa
     6241 tatatgtaga aggaaatgga tttttgtata acatggtaag gataatagta ggtgctttga
     6301 tagatgttgg tctaaaaaga agagctccac aagatattaa gtatatgctt gaatcaaaag
     6361 atagatgtca atcatcagat actgcaccag ctaaaggact atgtctttgg aaagtaacat
     6421 attaatcaat tatataaaac tctctttaaa ataaaaataa aataaattat atagttgaca
     6481 taaatggaaa aataaactat tatatatttt ataagagaga tataaaactt tatatttaaa
     6541 tcctgtgaga aagagagtaa cttctatgtg ttttatagag agctgaggat ggtggaagct
     6601 tggcaaataa gtattagtga aaagaacttt ggaggatact aattgaattt agtatgttag
     6661 taggtaatct cgccttaaga gaaagagtgg ataagtttat cttatcaatt agagtggtaa
     6721 cgcggatata tttcgtctct tggtttttcc aagaggcgtt ttttaatata tttaattatt
     6781 agtgtttatc tggtatgttg aacatttact aattgattag ctaagtttat caataagagt
     6841 ggtaccgcgg atatttcgcc tcttagtatt ttaaaatact aaggggtttt tttagtatta
     6901 aaatgatttt atgtgagtct aaattctcag agtcattcaa tattaagaat ttctataaaa
     6961 taaaaattat aatttaagat tgggaggaat taaaaatgaa ggaaaaagta gtattagcat
     7021 attcaggagg acttgacaca tcaatcataa taccttggtt aaaggaaaat tatgaagata
     7081 tagatgttat agctgtttgt ggaaatgtag gtcaggaaga taaaatggaa gatgtatatg
     7141 aaaaagcttt acaaagtgga gcatcaaagg catatgtgga tgatataagt gaagaatttg
     7201 taactgaaac tatatttaaa gctgtaaaag cagaggctaa atatgaagga aaatacttat
     7261 taggaacttc tttagcaaga cctataatag ctaaaaaatt agttgaagtt gctcataaag
     7321 aaggtgcaaa atatatatgc catggatgta caggaaaagg taatgaccaa gttagatttg
     7381 aagctacaat tgcagctctt gacccaacta taaaagttat tgcaccttgg agaatttggg
     7441 atataaaatc aagagaagat gctatagact atgctgaaaa acataatata aaggtaacag
     7501 caactaaagc taaaatatat tcagtagatg ccaacctttg gcatgtttca acagaaggtg
     7561 gagatataga gcacctagaa aatgaacata aaaaagatgt ttataaacaa tgtgtagacc
     7621 cagaagatgc atgtgatgta gctgaatatg tagaagttta ctttgaaaaa ggtgtaccta
     7681 aaaaggtaaa tggcgaagaa ttatctccag ttgcactgat tcataagtta aatgagttgg
     7741 gttgtaaaca tggaattggt gttatagata tagttgagaa tagacttgtt ggtatgaaat
     7801 caagaggtat atatgagact ccaggaggaa caatccttta tgaagcacat aatattttag
     7861 aaagtgctac tttagacaaa gatacattac atttcaaaca aatggtatct tataaatacg
     7921 gagaacttat ttacaatgga ctatggtatt gtaaattaag agaatctata gatgcattta
     7981 tggaacaaac tcaagataat gttacaggaa cagtaaaagt taaactttac aaaggaaata
     8041 taaaacctgc tggaatattt actgaaaatg ctctttatga tgaaggaata tcttcttttg
     8101 gaaatagtga actttatgac cacaaagatg cagaaggatt tattaattta ttcactttac
     8161 cattaaaaat cagagctatg aaagctggaa aataataaaa taaattattt aagagtgtat
     8221 aaaaacgatt tttaggtttt tatatgctct ttttttattt gaatttatta aattatacag
     8281 taaatagtat aaaaaaatat attatagttc caaatggctt aataatgtga aaatataaga
     8341 cctaaaatat aaattttata aatacaatag ttattgactc tctcattgta agagggttta
     8401 tactgaatct aatgaaaatt tatagtgagg agatagatta tatgagaaaa ataattgaaa
     8461 ttaaacatca ttcacatgat tatgagtgta tgtggaatgg tatagaagat ttatatataa
     8521 ataaaaccgg tgaatacctt ccaaacgatt ttttcttttt actgtcaggt tttggttcat
     8581 tttgttatat gaaaacaaat aaagctgatt tgaaaagaat ggtagctttg ggagatggaa
     8641 ggacaaaaca gatgtataaa tttttagcac caattgttgg atttgaatac aaacatcatg
     8701 agtttaaaaa gtatgagcaa gcattaaaga aagcaaaatc tgaaattgat gatggatatc
     8761 cagttatttt aggagcttta gatatgtatt atctaccata ttataagaag ctatatcata
     8821 aagaacatat tccttttcat tatatattaa tggtaggata tgatgatgaa ggaatatatc
     8881 tgtatgattg tggtagaaca gaattattac atctttctta tgataaatta cgtgaaagca
     8941 tgaattgcaa ttcccctgga ttaagcaaag aaaatactat ttgcacaata agaatgaata
     9001 cttcaaagaa taaatataac attgctagag aagctattgc tataaagcgt gatatgtttt
     9061 taaatccacc taaaggattt ttgggatata aaggttttga aaagtttatt aaagagttgc
     9121 cacagtggaa cactgaattg gataaggatg attatgataa gattttgacc aatatggtta
     9181 tgttttttgg aacagtacca acaattccaa atgcaatcaa aggaattaaa gaaccagata
     9241 ctgttcaatt taaaggtgga tttgataaaa tgagtagaat gctcaacagt attggggagg
     9301 aatacaaaaa caactctttt atacaagtag ctgatatttt tgataaaact gctattataa
     9361 ttgagaaaat atccaatatt ataatagatt acttaactca aacatgtgat gatacagaac
     9421 aacttccgtt attgttctct gaggtcttag agcatatgaa aacaggatat ttaatcttgg
     9481 atgtataaaa aatatattgt tgaccctaac attacgtaat agtgtaatat gaaaatatag
     9541 cttaaatata ttagtaggta ttgatggctg taaaattaaa atttgaggtg tggatatgag
     9601 aacagtgaaa caagtttctg atttaactgg aataagtgtg agggcattac attattatga
     9661 tgaaataggt cttttaaaac caaataaaat tacagatgca ggatatagac tttatgatga
     9721 tgaatctatt aaaactcttc aacaaatttt attttttaag gagattgata ttcctttaag
     9781 agaggttaag gaaataatgt caagccaata ttttgataag gttgaagctc taaaaaatca
     9841 aaaaaaatta cttattttaa aacgaaagag actggatgaa ttgatagagc ttataaatca
     9901 aactctaaga ggagaaggaa atattgattt taaagagttt gatatgagcg agtattttaa
     9961 tgttttagaa gaatttaaaa gagagcatag gaataaggta attaaaattt atggtagtgt
    10021 agaaaaatac aatgaatata tagaaagagt taagtctaat gaagagaaaa ttgctaaaat
    10081 ggctataaaa caatatggaa ctattgagaa gtttgctaaa gctataaaaa caaattttag
    10141 cagtgatata ttgaatttag gagaaaaatt tgatagatat aaaaatgatt gtttaaaaga
    10201 aaaacatcca aaattaaaag aattatatag aaagcttgta gaagatttaa gtaggaatcc
    10261 ttcttcaaca gaccttcaag aaatagcaaa agcgataaca gatatatcta aaaaagatta
    10321 tgaaattttc tctatggata ctggtgatga caactggtat tatatggttc aaaattatct
    10381 agtaaatcct atgtggatag aagaagtaga taaaaagtat ggaagtggag caggaaagtt
    10441 tattggacaa gtactaaaga cttatctaag agatagaaaa ccaaagataa atacattgta
    10501 tgaaaaactt gtagaagatt tgagtagaga ttgttcttca agggaagttc aaagcattgt
    10561 tgaagaaata gacaatgaaa tgaaaagaag taatgaattt tataaaatag acaatggtga
    10621 aagatacttt gattatatgt cagagcttta tttacaagat tctaactata taaaagtaac
    10681 tgataagaat tatggtgatg gtgcatctaa gtttattgga gaagctttta agatttattt
    10741 tgataataat aattgttgaa aatttggaag taaaaaatat gtaagtttta taaaagcaca
    10801 aaaataagga tgtagattag ctccatctat atccttattt aaagttatta aaatatatag
    10861 tttacatcaa acttaacact ttcaataata tttcccaaat atgtttttat actttcaact
    10921 tcttctaaag attttaattt attttcagta taaattgctt tgtccagaat attaaacctt
    10981 aatcctattt catcaaagta ctcatgattt aaaactttgt accaatggtt tttttcttta
    11041 ttccaactcg tagatattga atcagcttct ttttgagctt tttcccaatc ttcattttct
    11101 atagattttt ctaaaacaga tatattgtct ttatatcctt ctgtaaaatc atatagttta
    11161 ttgttaacgt aaaatccaaa taatacaaat aagatagtcc atagtataac aaatgttgta
    11221 gatttcaata ttaatcaccc tttttatttt gaataaatat tttgtcattt tcatctaaaa
    11281 cacaaataag aacatcttta aaagtttcta tgtgattaga ttttaaaata cccattaacc
    11341 agttagtatc tttttgagct atgtctagat ttttatttat tattctacca tccagtataa
    11401 gtgggatagg taaatgatta aaagctcttg gaggagtact attgtagctt gatgctggta
    11461 caacacttag attaccatca gtctccaaaa tagcatattg tacatctttt aggttaaagt
    11521 atccttgaat cctaagttgt tctaataatt catctatact aattctttct tttttaagct
    11581 ctttatatac aatttttcct ttatctatta atacagaagg tttacctgat aaaaatgaac
    11641 ttaattttct gctttttaat gataagaatg aaattagagt ctgcatgatt acaagtccag
    11701 atattgctgc aacaccattt atgattggta tattattatt ttccattggg acagatgcaa
    11761 cttctgcaat taatagtgtt ataactaaat caaaacagtt catttcagct atttcacctt
    11821 ttcccatgac tctaagtgca attagcactg ttatgtataa tataatactt cttattaata
    11881 ctactgtcat atctatcaat tactccttta aaaaatattt acacttagtt agtatatcct
    11941 atataaaaaa tttaattcaa agtataaaaa accttaaata attggattca actatttaag
    12001 gtttttttga taattttaat attaaatttt ttatggattt tctgttactt ttatttattt
    12061 taataacaga ttcaacaaaa ctctttttat ctcctaattt taagataaaa tcaggatatt
    12121 cttcaaattc attgagtttt attaatttga aagaagaaga tagattttta aagttaataa
    12181 ttttagagtt attcactaat acacttcttt ttttaaaata aatttctttt ttacttatat
    12241 ttagtatagt taatatttgt ttaagatata ttattatatc ttctggagtt ctatcaaatt
    12301 tgagttcaaa attttcatct tcaaagtagg gaatataata taaaggtgtt ttgagagcag
    12361 gtaatttatt atataattct tcaagaatat cgatattttt aggggagtta aagaaaaagc
    12421 atttacatac attcattaaa tccacagcat ctgaaagtga gttatgttta atatctcctt
    12481 ctacagaaaa aatttttttc atattcagta aagatatttg cttagataag attctattat
    12541 tgtatgtaat atgttgagat ataaaaggtt gaatgtcaat catcatatta aataactcta
    12601 agcatttacc tgtatattta tacactctaa atgaagttag aaggccagtt atatcaaaat
    12661 caccccaatt atatattgta acatcatcaa atttacaaaa ccatttataa aaatcatcca
    12721 taacatataa aagattagga gcattattga tatctagttg gttcaatttg gttaaatttt
    12781 tacatttatt tgaaagtatt ttattgtatt ttggcttaac taaagagtaa taattatcta
    12841 ttgtattaaa ttcgttatca actaaaactc caccaataga aattaattcc gcaccattat
    12901 attcttttgg tttattttta ttatcatcta gtatattaaa ttcaaagtct ataaataact
    12961 tgtatttcat aaatctaaag cacatcctca ggtaaattat ttattgagcc taagcatcat
    13021 aagaatcaat agatataatg actctaaaca tcaaaggttc attacaactt ttatttattt
    13081 cataatttaa ttcaaataaa tcttttaaga tataatttat aagtattctt tcccaaccca
    13141 tttttaaatt aactttagag tctattaata tattttctat ctttttaaat atttctatat
    13201 ttgctggtat tatactgagc tcaatattac ttttaaacgg gttagactgt aaatctgtta
    13261 taagtatatt ttttaattcc tctgtaagtt cagaaattaa actatcacct atgtattttt
    13321 ttatgatttc ctctctaatt tcttttaaat ttagcaatat tagtacctgc tacttacata
    13381 gtagcttttc ctttcctttt aatactatta ttcatttttg aatcttattt agatatattt
    13441 taagattaaa agtctttagc tatataattt tttacccatt tttaacttat attaacatat
    13501 tacaggctta tatctccacc ctgtttacat tgaggatgga gtatattgcc tattttgata
    13561 aaaatgatag gttgctattt gcctattcct ttttctgata atttttctaa catatctttg
    13621 gtcattttat ctaaatcata actaaactta aagttccatt cttttactgc actactactg
    13681 tctagagagt taggccaaga atcagctata ctttgtctta cagggtctac atcatattct
    13741 atcacaaaat caggaatata tttttttata gaatcagcta tttcttcagg agaaaagctc
    13801 atagcagtaa tattaaaagc atttctatgg atgagtttat cagctggagc ttcgattaaa
    13861 tccactattg attgaagtgc atcaggcata tacatcatat ccatttttgt accttctgct
    13921 atgtaagatt tatatctctt attttttaat gcctcataat atatatcaac tgcataatct
    13981 gtagttcctc caccaggagg cgtaacataa gaaataagac ctggaaatct aacacctcta
    14041 gtgtctactc caaattttga gtgataataa tcacatagta attctccaga aactttagtc
    14101 acaccataca tagtattagg tctttgtaat gtatcttgag gagtcatatt ttttggagaa
    14161 ttttcaccaa aagcagcaat tgaactaggt gtaaaaaatt tacaatccaa ttctttggct
    14221 atttcaagac catttattaa tccattcata tttaagttcc aagcttctag aggtttactt
    14281 tcagcaactg cagaaagtaa agatgctaga tgaattatag tatctacatc atattttttt
    14341 gcaatttcaa aaaaacgatt cttatctgta acatctaata tctcaaatat accagattca
    14401 catactggat taccttcttt tactctcctt gaactagcga ttacattttg ttctccatac
    14461 tcatttctaa gctttattgt taattctgaa cctatttgtc ctaatgcacc tgttataagt
    14521 atttttttca attttacaac ctcctaaggg tttaatttat gtagtactac ttatttttat
    14581 tttagcaaat cttttgttta aatacaaaga attaaagata ataatatacg acttaattga
    14641 atgaagtgca gtaagtgcgt aaaaatttaa agctaatata taatggtcta ttgtataaca
    14701 ataaaagagt agattaaatt attatatata gattgtgtga ctaagtcaca gaaaatagag
    14761 ctaatttaat atataataaa agcatgtcaa gtaaagcttt aaattaaagt aactttatat
    14821 aaaaagtaat ataaattgat aaaattataa atttatttat agtgaatata ggttggattt
    14881 tatagataca aaaatagtat atatgatatg tagaccatta gcatgtttaa agtagcaaaa
    14941 catataaaat aaaatttgaa aggaagtata aaaatgacaa gaccatcaat atatcatagc
    15001 caaggataca cttgtgcaga ggcattaata aagtcttata atgaggaaca caacacagat
    15061 ataccaatct caataggaag tggtatgggg gttggaatga atgttggaag tgtttgtgga
    15121 gctgtaaatg ctgctgttgt tataataggg tatttaaatg ggcgaaatag taatttagat
    15181 gaaaatatag caaggaagta ttcaagagag ctattgaata gagtaagaaa taaatacagc
    15241 tcagaaatat gtgtatctct taaaaaaaat aaagtaactt gtgaagaaat aataaatttc
    15301 acatatgatg ctctaaatga tatgctaaaa aatcaaaaat aattctaaga aacaagtatt
    15361 ttacattcga tagaatactt gtttttttat gatattttta ataagtatta gtttattata
    15421 atttttaaat caattttatt atattttaat tgaaataatc tactttgaaa attactaact
    15481 gacaaaagaa tatgattata gtatagaaaa aatgtaaatt atttaatatt aagtgagagt
    15541 atatgcttac ctatataaaa tcgtataaat taatggctaa atttataaat tataaagaaa
    15601 tatataggaa aataaaagaa ttaattagta taatataaag ttaaaaagtg aaaatttata
    15661 taatttattt ataaagtaaa gaaaaaatag aaatttgtaa taaaataaaa agtttatgac
    15721 ataatatggt ataattagta aaaatataga gattggagga attgctttgt ttatagatga
    15781 agaattagaa ggttatatat taacatgtaa aatatctgaa gactttaaaa atatacctga
    15841 atatagtgat gaagagtttt atgttacagt ctataaagat gaaagttctg actctgggta
    15901 ctatgcttta ttagaaaata aagaagaaag agttgtatgg gatggagaag ttgttgccaa
    15961 taatattttt aataaccttt ggattgtaat aaataaggtt aaaactggat aatagtctaa
    16021 ttatatagta tttgtaatat tttaaatgaa tttttacata tttgagatga gtaaataaca
    16081 aagattattc gatactggag gagtaattca atggaatata gttatagtaa gatgaactta
    16141 aaaaaagggg atattgtaga ggtaaattta gagaaacaag ccaatgtaat attgttagac
    16201 catataaatt atgtgaaatt taaaaatcaa agaaattatg attactatgg tggatttgca
    16261 aagaaaaatc catgtagaat gagagttcct aatactggaa catggtatct agtagtaaat
    16321 caagatggaa atagtggaat agtaaacttt tcaatcaata caattcaaaa ttaattttag
    16381 aatattggat attcttactt tttgtacttt ttatatagtt aaaataaaat taataagcaa
    16441 ttattataaa ataatgtggg tgcctcaaaa tgaattttat aattcacgag acactctttt
    16501 ttatatgaac tcaaatatac tttatcattt caacaatgaa aaaaaggcgt atctgtgttt
    16561 tgagatagcc tcatttatca tatatcatat atagaatttt aattattctt aactaaaatt
    16621 ttttccatag gttatctgta caattaaaat atttattgtt agcatacagc tccacctgta
    16681 aggtgtaaaa gagcctctag tatctcttct tttctttcca aaacttcatc tgataaaagc
    16741 atttctataa atttatcagc accgattcta tcgatagtta ttccaaaacg ttcacctgtg
    16801 ttaccctgtt ctctaaataa aagaattgct ttttcaatta aagtcataag ttcctctttt
    16861 gaaaataatc tatcaatctg tgttccagga cgaactgatt ttccccattt ccctcctata
    16921 tagactttat aaccagattc tttttcttca atactatcaa aattacaact ttctatacac
    16981 ttaccacagt tattacatag attactatct atttcaagtt tacctttatc tgttaattta
    17041 gctgctttaa caggacagac ctctacaaca gcacattttt tacaaccaac acaaagctct
    17101 gaatcatagt caggtacacg ttgaccaaca attccaagat cgtttaggtc aggtttaata
    17161 cagttattag ggcatccacc aacaccaatt ttgaacttat gaggtagttt tacatcatac
    17221 caatttttgt aaaattcttc gtgtatttca gcagcaagtg cctgtgtatc agctagacca
    17281 tgaacacaaa cagtaccttt acaagccaca acaggacgaa cccttgatcc agttccacct
    17341 gttattagat tttcgctagc aataaattca cttagagctt caatatcttc aaattttaca
    17401 ccaggtaatt ctactgttag tctagtagta aatgctaact gaccgtttcc gaatttttca
    17461 gcagcttctg caattttttt tgcttgtgat gcatttatta caccatttac agttattata
    17521 cgtgctgcaa aatgttctcc atccctgctt ggtagaaaac ctctaccttt tacttccttt
    17581 ttttgttctg ctgtaacatt actcatattt actcctccat taccttaaga tttggataaa
    17641 atagtattcc accttcaaga actttcgtat ttgtatagcc aaagcgtctt aagcgatttt
    17701 gcgccatata gctattttta cctttagcac atataagaag aattttttca tccttagcaa
    17761 ggccttcaat ttctccatta atttcaccaa caggaatata acgtaaacta ggaatagaag
    17821 gagcttttga aacatcaagt ttagtccaac tgtcaaaatc ctcaatttcg tcaagtaaaa
    17881 cactatcaag ttctccatta agtttatttt gtaaaacatt tactgccact acaaaagggt
    17941 gaatagctgt tgaaaaaggt ggtgcatatg caaggtccat actttctaat gaataaaggt
    18001 cagcgcctaa agttattgca gtagcagcga tatctactat tttatcaacc gctccaggtc
    18061 ccataacttg aacacctaat aattttctag tatttttttc agcaaccatt cttataataa
    18121 aattagatgc acctggataa taatgagctt tatcatcagt agctatggtt acagagcaaa
    18181 cattataacc ttctttttca gctatttctt tacttagacc tgtttttcct gcattgagct
    18241 caggtaattt tactactgtt gttccaagaa caccattgta agttttagat tttccagata
    18301 tattttgtgc gcaaattcta ccctcatgat ttgcagatga ccccataggt gaccatgtag
    18361 gtttatttgt taaagaattt tttacaaaag cacagtctcc aactacgtat atatctttgt
    18421 catttgtaag catatattca tctgcaataa ttgtattatt aggggcaaat tctaaacctg
    18481 tgtcttttag aaaacctgtg ttaggacgga ttccaactga cataaccact aaatctgttt
    18541 taatagctct atttttagta cgaagttttt caactttatt ttcaccttcg atacctacaa
    18601 cctggtcacc tgtaaaaatc attatgcctt tatcagccat atgattttca acgtattcag
    18661 caaaatcagt atcaaatcca ggcataacat gttcagccat atcaacaaca cttacacgta
    18721 tacccattgc agaaagattt tcagcaattt caagaccaat gaaacctcca ccaataacaa
    18781 cagctctctt aataccgttt tcaatagaat ctcttagttt tatagcatca tttggagtac
    18841 gcacaaagaa tactccaggt aaatctattc caggtattgg tggttttatt gggtctgccc
    18901 ctgtagcaat tacaagtttg tcatagctta gattttcttt ttctcctgtt gaaagcgttt
    18961 tcaaagttac ttgttttgca tttctatcaa tagatgtaac ttcaactcca caacgaactt
    19021 ctgctcctgt tagtttagaa aaactttcag gtgtatttac gattaaagat gatttatctt
    19081 caattatctt accaacgtaa tatggaagac cacaacctgc ataagaaata tcatcacctt
    19141 tatttagtat tgtaacagag caattatcac ccatttcacg ttttattttt gcagcagttt
    19201 ttgttccagc agcaactcca cctataatta atactttcac aatatatcac actccaatct
    19261 actttataac tctataataa aattatactt cttgacaata tatttgtaaa atactaaaat
    19321 attaataaaa tcataagcat ttactaatgt ttgctaaggt tgtgataata tgacaattcg
    19381 tagtcttgaa atctttgtta aggttgctga atgtggtaaa atgagtgaag tagcaagaaa
    19441 tatgtatatt acccagtcat cagttagcca agctatttca gaaatagaaa aagagtatgg
    19501 tgttaagcta tttgatagaa tttcaaaaaa attatattta actgaggcag ggaaaaaact
    19561 tcttggatat gggaggcatc ttttagctgt aaatgaagaa atgaatgatt gtatgaagca
    19621 ttgtgcaaaa aatatccgta taagagttgg ggcaacagta actgttggta catgtgtaat
    19681 aagtccaata atgttagaat tatacaaggt aaatcctctt atagaacctg aagtatttgt
    19741 agaagataca agactgattg caaaaaaatt acttaatagt gaattagata ttgcgattgt
    19801 agaaggaaaa attaagcacc cagatattgt tacaaaaagc attattaatg ataatcttgt
    19861 acttatatgt tcacacaagc atgagtttta taaaagagac tctataaaag tttcagaact
    19921 ttcaaatcaa ccattaatta tgcgtgaatt aggaagtggt acaagagcac aattagaaaa
    19981 gcaattaaaa gaattaaaaa tcccaatgaa tattagatgg tcatgttata actctgaagc
    20041 tatattaaga gcagttgtag ataattttgg cattgcagtt atatccgaat tacttattga
    20101 ggattattta aaaaagcatc ttttgtgggc ttgtgatatt gaaggtatta atttacatag
    20161 gacatttgat attgcatatc atagaagcaa gttttttaca gaaaatattt cagcattttt
    20221 tgatatttca gtagaatatg ggaaaaaaca agcgagaaag aagagtagaa gtgtaaacag
    20281 tttataatat atctaaataa aaataagagt atatcaatat actcttattt ttatttagat
    20341 atattagcct atattaacgc caaaattttt acacaatcct gcaagtccat cctcaaatcc
    20401 agaacctaaa gcattaaatt tccattctcc attatgtcta tatagttctg ccacaactat
    20461 tgctgtttct atgctaaaat cttcacccaa ttcatattta ataagttcct cattagtttc
    20521 ttcattatat attcttatat atgaattttc aacttgtccg aaattttgtc ttcttgtaat
    20581 tgcttcgttt atagtaacac taaatgatat tttagcaata ttttgaggta ttttagataa
    20641 gtctacattt atttgttcat catcaccatc accaacacct gttctattat cacccatata
    20701 ttcaacagct ccagaagcgt gttttaaatt attatagaat ataaagtctc catcattcgt
    20761 tacttttcca tcagttccag ttaaaaatgc agaggcatct aaatcgaaat caaagccacc
    20821 atcatattta ttaatatccc atcctagtcc tactattact ttttttagac cagggttact
    20881 ttttgttaaa cttacttttt gtccttttgc taaagttata cccatttaaa ccaactcctc
    20941 attataaatt ttttattgta attattactt atatgtatta attaattcac gaagctcttc
    21001 attttgacca attcctaaag cattaaattt ccattcttca tttctacgat aaatttctcc
    21061 tgccaaaact gttactttac cagaaaagtc ttcttgaaga ttatatttaa ataattcttg
    21121 cttggaattt gaatcaatta atcttataaa agagttgttc atttgaccaa aatcctggtc
    21181 tcttttttta gctttgtata tagaaactcc aaaaactatt ttatgtacat attcaggtat
    21241 gtcttctaaa ttaacaatta tttgttcatc atcaccttca ccttttccag ttaagttatc
    21301 tccagtgtgt ataatagctt tagaagggtg tttaagattt ccaaaataaa ccaagtcacc
    21361 tctaacattc attttatctt ggttagtcaa tgctattgca aatgcatcta ggtcataatt
    21421 ttttttaccc aatttattca tatcccatcc taagcctact actagatttt ttacaggatt
    21481 attatctttt actaagctaa ctctttgtcc tttttgtaaa ctaacactca ttttaagttc
    21541 tcctttttat atttttagtt ttattgatgg tatcaagtat aagaaccata ttagctatat
    21601 tatatacgta tttaggctaa gttggctata tttataaatt atttattata taactacatg
    21661 aatattttat aatttaaaca tattgacatt atatgcttta aattattttg tagttttata
    21721 atatttaaat ttgtatttga ttgttataaa gtaaagtaag taataaagtt agactcaata
    21781 attctaaaat ttctaagcat actatctaaa tgagaacgga tttggaaata cttgtataaa
    21841 acaataattg atacatttaa tttttatctt aaaaacaaca attataatat ataaatagca
    21901 agtataatat ataaatagca agtataatat aacatataaa aagttgaatt tgtatatgtt
    21961 aattatactt gctatttatt tgttagttat tctatttttt taaatccatt acctaaagct
    22021 tcatgtatat ctgtaattat aataaaagca ttagggtcga cattttttac taattttttc
    22081 aattcgacaa cttctttctt ttcaactact actaaaagta catttttatt ttctccagta
    22141 tatgcacctt ctccttttag aatagttgca cctctatcta aatcttccat tattttttta
    22201 cttatatctt ttgaaaggtc agatataata gtgaatgatt tggaataatt aaatccttca
    22261 ataagcaagt cactaacttt tactaaaatg tataaagcca cagttgaata aagtgcaatt
    22321 tcaacctgtc tatttactat acctgataaa acaactacaa cgcagtctac aatacccatt
    22381 aaaacaggta tactaaatgt aggaaaatat ttatttagta ggagtgccat taaatcagtt
    22441 ccacctgtag agccatttat tctaaaaata agtccttgac caactcccat taaaatagaa
    22501 ccagatataa ttgcaagata catatcattt gttatatcta atgtagccat atttgcagta
    22561 agcttaagtg ctatggtaag aaaaattatt cctaaaaccg ttttaaaaca atcttttttt
    22621 gaaagtattt tgtaagcaaa tatgaataat ggaacattta aaagtaaatt gacaatccaa
    22681 agttctacac cgaataatga atttaaaaca actccaagtc ctgttatacc accagcagcg
    22741 attgcatgtg gattaaaaaa taagttaaga gaaatggcca ttaatataca gcctacaatt
    22801 aatattaaaa tttctgaaaa agttattcta tcttttttca ataacatcac tccttatata
    22861 tagattataa tatatattat atagtttttc caatttttaa taaaagaaat aaaaatatat
    22921 tataaaaaca atttgattgg aattttcaga aaattaatgc tataattaaa agtaaattta
    22981 aagggaggtt ataaaatggc taaattaact ctagaacata taaaaggaaa tacatattat
    23041 attccactcc ctacaatagt aggtgtatac gtagatggta aggatgcaat tttaattgac
    23101 agtggaaata ataaggatac agctagacaa gttttaagat tattagaaga acataattta
    23161 aatcctaaat taataataaa cactcattca aatgcagacc atataggagg aaatgcatat
    23221 ttgaagaatc aaacaaaatg caagattgct acgactaaaa ttgaaggata ttttacagaa
    23281 aatccaatat tagaatcagc atttttatat ggtggctatc caagtaaagc actgaagaat
    23341 aaatttttat tagcaaagga aagtgaagtt gattatatta taccttcaaa tggcaaaatt
    23401 gtagatacag aacttgaagc gatttctctt ccaggtcatt attttgaaat gattggtgtt
    23461 agaactccag ataatgtttt gtttgttgca gatagtctta caccagagaa tataattact
    23521 aaatatcatt ttttcttcct actggatata gattcacagt ttaagacact agaaaaattg
    23581 agaatgttag aggctgattt ctttgttcca agtcactctg tcaaaactac agatataaaa
    23641 agtttaatta atattaataa gaagaagatg gaagaaataa tagataatat taaaaaggtt
    23701 tgttatgagc cagttatgat tgatgaagtt attgaaaaaa tgtgtgattt gtacaatgtc
    23761 aagcttgatg ctaatcaata tgtgttggtt ggaagtacaa tacgttctta tataacttat
    23821 ttatatgaga ataatatggt tgaatatata tttgatggtg gtaagatgat gataaaagct
    23881 gcgtaaatag taataatttt caaattatat gatgaaattg ttttagtatg actgttattt
    23941 gaaaagtaat ataaaaaaat ttatataaat aagctaagat gattgatata aagttactga
    24001 taattttaag gtaatatata cgttactata atattatgtt attatttgta aataagggga
    24061 taatttataa gcaaattaaa gaccttaatt tacaggagga atagtgtata ttatgaataa
    24121 aaaattcaaa aaattcagta aaaaactaag tatattaatt ttagttttga ctatgtttct
    24181 ttttaataat ttaactgcaa atgcacagat taaagaagat tcaataatag gaattgatag
    24241 atatgaaaca gcaggactta tagcggatag acaaacttat gatactgtaa tattagttaa
    24301 tggagataaa aatttatctg atgggctttc atcaagtgga ttagctggag ctattaacgc
    24361 accaatactt ttgactaaaa aaagtgaaat accaaaagct actttaaata gactagataa
    24421 taagagttta aatgttgtaa aaaaagtata tataattggt ggttataata ctattgaaaa
    24481 ttcagtagaa aaagatataa aaagaaaagg tattcaagtg gaaagaataa atggtaacaa
    24541 tagaattgaa actagttata atgtagctaa aaaaataaat gaagtaagta gtgtaaaaga
    24601 ggtaatgctt acaaatggat ttgtaggaga ggctgatgct atgagtatag cacctgtagt
    24661 tgcaaaaaat aaaggagcta taatacttac agatgggaaa tcagttccat ttaagactga
    24721 aggtttaaat gtttacgcta taggtggcaa atctgcgata aatgaggatt tagtaaatga
    24781 aactaaagca attagaatcg gaggaaatga tagatttgag accaataaaa aggtaatgga
    24841 aaagttttat aatggagcta cagattttta tataacaaat ggatatcaat tagtagatgc
    24901 actaacatta tctcctttag ccaaagaaaa accaatcgtt ttagttgctg atggaagtaa
    24961 taaaggtatt ttaaaaggag ctaaaagtat aacaaaagtt ggaggtattg atgccaatat
    25021 atataaacag tgtttagata tgattaaata taataatatg gatatgactc caaatatttt
    25081 aaaacactta acttcagttg aaggaaatga agtttctgaa atacttatag aatcagataa
    25141 tttaggtgtg gttgttgaaa agacgaatac caataaattt gagtttgatt acgtaagtgt
    25201 aactaatgaa aaaaattgta ctttttctgt atataaagaa aattcttcta ataatataaa
    25261 aaatggaaag ctagttgtaa gtgctaagaa aaaaatagat aagaaagata gtgatttgca
    25321 agatatgaat ggcgacaata tgataaatgc aaataaagat aggatggtaa atgtgataaa
    25381 aattggagtt cccgataaaa tgtattctaa ttttaaagta gatgttgaaa gtggttcagt
    25441 agaactttat aatattaaag gaggagctac tgttgatgtc aatgacggaa ttgctaacat
    25501 tgttgataac aatgtaacaa atcctttcaa tataaatact aatagtggga tttcaggtgt
    25561 aacagctgaa actatatcat ctgaaataaa atttagagca aacaatggaa ttgtaaatgt
    25621 aacagctaca aatataaatg gcaatataag tttatttgga agcgataata aagatacttt
    25681 tgatggaata tttaaattaa atctgaaaaa agaaccatca aatttacact tgaagttaat
    25741 tggaaatggg ataaataaat tgccagaagg ttggtctaaa gattatattt taggaaatgg
    25801 acaaccaatt attgaagtta aaaataatgg cataaataat atatcaattg gagaataaaa
    25861 acatatgaaa ataaagttta tatagtttt
//
LOCUS       DAJMZY010000052        25619 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.052, whole genome shotgun sequence.
ACCESSION   DAJMZY010000052 DAJMZY010000000
VERSION     DAJMZY010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 25619)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25619)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25619
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.052"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            complement(<1..921)
                     /locus_tag="OE968_002098"
     CDS             complement(<1..921)
                     /locus_tag="OE968_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease domain-containing protein"
                     /protein_id="HCP7219377.1"
                     /translation="MFILKRVYIDFEMNMPNSKSKRAVFNSDIIAIGAVMYDEKTKNI
                     DKFKSLIRPVSNEELYPHIQELTHISSEELKSAPSYEEVMRKFKKWLGIFSDIKGIYT
                     FGNLDLTCFNNTDMRSAKKNNHPRFVNNIRDLFVDIKEKYINCGMRCMNYISLKNLLE
                     FVNLEFSGDAHDPLNDAYNLFILDEAITNNVDIQNLLIIRDIIRPPFNDINSNLDNCF
                     NKFKESLYKKEGNYNIVDFSVEIIKTVRMYLLTIIDVNIQNLEIMKDISKKMDTIDKL
                     KDIEEGYFYLLEDVYFDMKDVLEDLMLYRMN"
     gene            complement(960..1820)
                     /locus_tag="OE968_002099"
     CDS             complement(960..1820)
                     /locus_tag="OE968_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011986089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiocytidine(32) synthetase TtcA"
                     /protein_id="HCP7219378.1"
                     /translation="MSELSGKGCEIIVPFEERLPVRDIEKSIIKKYRKNLWSKFMKAI
                     RDYKLVEEGDKIAVAISGGKDSILMAKMFQELKKHGQVNFDVEFIAMDPGYHANIRQL
                     LIDNCEYLNIPIHLFDSRIFEIADEIAKDYPCYMCARMRRGALYSKAEELGCNKLALG
                     HHYDDVIETTMLNLLCAGNFKTMLPKLNSTNFEGIKIIRPLYYIREEHIIRFIQNSGI
                     WPLNCACMVAAKKTGNKRYEIKDLIKSLESNFKNVEKSIFKAAENVNLDSVLGWQKDG
                     EKHSFLENFE"
     gene            2089..2298
                     /locus_tag="OE968_002100"
     CDS             2089..2298
                     /locus_tag="OE968_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat associated protein CotJA"
                     /protein_id="HCP7219379.1"
                     /translation="MENKTRDIKKNCGPSLARPYINNQIFTEMYCLSDALKFGTIFPE
                     LNLLESEMYNKELYAKPKKYRGGRR"
     gene            2298..2564
                     /locus_tag="OE968_002101"
     CDS             2298..2564
                     /locus_tag="OE968_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat protein CotJB"
                     /protein_id="HCP7219380.1"
                     /translation="MKDSSRAELMRKVQETSFACVDMNLYLDNHPDDKNAINTYNSLC
                     NQFAQARYAYENKYGPLTNFGYAPSRCPWQWADQPWPWDREFNY"
     gene            2593..3165
                     /locus_tag="OE968_002102"
     CDS             2593..3165
                     /locus_tag="OE968_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000265278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HCP7219381.1"
                     /translation="MWIYQKTIQHPVNIKTCDPRMAKFLITQFGGPNGELAASLRYLS
                     QRYTMPTGNMRALLTDIGTEELAHVELICTMVYQLTSDASPEELKAAGLGSNYAQNGY
                     GIYPTDSNGVPFDVRPIAVMSNPVTDLHEDMAAEQKALATYYQLINLTDDVDVIDVLK
                     FLGQREIIHYQRFGEALMDAYELEESQKMF"
     gene            complement(3400..4590)
                     /locus_tag="OE968_002103"
     CDS             complement(3400..4590)
                     /locus_tag="OE968_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HCP7219382.1"
                     /translation="MNFNQKRIAASIMATAIIMPTMGNLAYANESEVESVSIESRTIT
                     GNAVNFRKGPGTNHESMGKLYKGDKVEYVGKEGSWVKVKYNGNTGYVHGNYVAINSLG
                     SSNESSDTSVKSTKVVTAKGLNFRTGPSTSSSKISTLGYGTEVGYISESNGWSKISSN
                     GRVGYVSSKYLGTSVNDSTNENAENSSNDLVKGTKVVTAKSLNVRTGPGTSHSKIATL
                     SYGTEVGSISESGGWTKISYGNQTGYVSSQYLAEKGSVDTSIPSYSTNSPSQGADSVI
                     SFAKTLLGKPYVWGAEGPNSFDCSGFTQYVMKKSVGVSIPRVSRDQSKYGTYVNRGDL
                     RSGDLVFFDTQGSNNGSVSHVGIYIGNGDMIHASSGSSKKVTISNINSSYYSSRYVNA
                     RRVL"
     gene            complement(4850..5281)
                     /gene="dut"
                     /locus_tag="OE968_002104"
     CDS             complement(4850..5281)
                     /gene="dut"
                     /locus_tag="OE968_002104"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HCP7219383.1"
                     /translation="MYNLKVKKLNDDAIIPNFAHKGDAGMDLYSIEEVVIPPGETKLI
                     KTGICIELPTMTEAQVRPRSGLALKHSVTVLNTPGTIDEGYRGELKIILINHGKNDFK
                     VEKHMKIAQMIVKPIYDINIEEVKELSDSERGKGGFGSTGF"
     gene            5394..7622
                     /locus_tag="OE968_002105"
     CDS             5394..7622
                     /locus_tag="OE968_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IA DNA topoisomerase"
                     /protein_id="HCP7219384.1"
                     /translation="MKLVLAEKPSVAKTIASFLGAKTRQDGYFEGNDYIITYAVGHLV
                     SLYDMKDYDKDKYSGSWKMNNFPFVPEDKFKFKIDSSKTKQFNTVKKLLNRKDVEYVI
                     NATDNDREGELIAFLIFLLAKNKKPVKRILVNEWTPEDITRGIKNLKDEDEMRNLQAA
                     GYTRLITDWLIGINFTSVATLKYGNGKLLNIGRVILPTVKLVYDRDMEILNFVPKTYY
                     EIEGHFKAEAGEYKGKYVKGKESKFDTLEDANKIIASITSETGKILDKKVTMSKEYAP
                     KLFSLTSLQGYITSKYSNFTSDKVLNVCQSLYEGNGKGGYITYPRTDSIFLEESLASK
                     ASQTLDKLKVGLEYENKIKFSKTKRVFDSSKVDSHSAIIPTYIIPKSLSKDEQLVYDA
                     IKDRFVANFMPPAEYENTEIKTEVDNCTFLTKGKVLKSKGYLEVYNKEEKNDLLPLVN
                     KDDVVDVLEIKPLTKQTTPPKPYTEDTLLKAMKNCGKNVPEEDTTVLSGYSIGTSATR
                     ADVLKKISQVGYVKKKGKSYSITDLGKNLVEIFPVKDLFDVDYTGKLEKSLSDIQKGK
                     YTRKEYLTNIISFIYQNVNIIKQDASKNINTEAYTFDSKTKKFTKTKEKKQKKDVTNT
                     EKEVAISKDSNNKKEVKNGDENQSLGKCPICQGDVLEFDKGFACKNHKECKFVIWKND
                     KYLSLYKKKVNKTMVKNILKKGETKVKSLTAKNGNKFDATLKYDKNPDTGYFNWKIEF
                     DN"
     gene            complement(7733..8218)
                     /locus_tag="OE968_002106"
     CDS             complement(7733..8218)
                     /locus_tag="OE968_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HCP7219385.1"
                     /translation="MDNNNILKIADSFLDFLFVLENNIFKESDLLKKFQNNSDIMKAY
                     FEECPMAPSHAKVILYLMTSNSSSISQIASNLGILKSNMTPIIDRLVEHGLVNKFPDP
                     KDRRILRVELTDKAFKLFDAVKAILKESLVKKLSNLSEEELTLLDEHTLKLSEIVKKL
                     G"
     gene            8470..9693
                     /locus_tag="OE968_002107"
     CDS             8470..9693
                     /locus_tag="OE968_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HCP7219386.1"
                     /translation="MKRYLIVFLMCSSLFLVGCGKTEESEPEKPIAVSVQKAIGGEIE
                     NTNSFSGTTKVKDETAVTAQTVGTVQEVYVKLGQNVRKGDELLSISSPELENSVKQSK
                     ASLDLAKASYSSATGGSLEAQVNQAKTALDNAKIQYEESQRNYDNNKILYEQEVISLD
                     QFKKIEFSLEQTKQQLDSAQRAYDTATSKSIPQAKALAKKQLDQAQVSYNLAMSNLDK
                     LTLTSPVDGTITAKNFDSKEMITQSQPAFIISNPNILEVDLNVAESDIGKFKKDGNVD
                     VIIEDQRILGKIDYVPSVVDPQTSLYPVKVLVNNTNNKFKAGMSAQVNLSVEKENGAV
                     TVPKKAIFEENGKKYVYIATKDNIAKKHLVQTGIVTEDKIEIKSGVSDKDTVIIGGIS
                     LISDGTKIFPVEKEK"
     gene            9697..12831
                     /locus_tag="OE968_002108"
     CDS             9697..12831
                     /locus_tag="OE968_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter permease subunit"
                     /protein_id="HCP7219387.1"
                     /translation="MNLTQTSVKRPLTIIMVFLVLIVFGGIGYKKMSINLMPDIEIPV
                     VMVMTTWTGAGPQDVDEQVSQKVDESLSAVSNVKSTISSSQESVSMVVAQFEFGTNLD
                     EIMNDVRSKVDALQTSLPDDAAKPTVLKLDMNAQAIGQLVISGGNENSSQALRKYAED
                     VIQPKIESIDGVTSADLKGGEKAQVNVIADPAVLSNYGVSLSTIKGVLSSSNKTFPYG
                     SITQGEDKIVLRAIDKLESLDDIKQIQIPVKGGNTVRLDNLCSVDYGYADKDSIYRYN
                     GKDSLVIDISKQQDANTVKVMQSAYKYVDELNKENPQFKIKIANDTSSYISESINSVM
                     SNLLISAVIAFIVIFAFLKSVRASLVVAVAIPISIIGAIAILYFTGESLNLITASSLV
                     ISVGMVVDNATVVIENIFKYRKSGRLSLDDCAIEGTRTVTNAILASTLTTIAIFLPIM
                     FTEGIAKITFGALGKTLIASLAFSFIGAITLVPSVFAKLSRGKNSQKMQEKDSPIFDK
                     VSEAYKKLLSVCLRHQRLVVISSLLIFVASLFGMGFIGMDFMPAADKGELSISIELPK
                     GLSLESNDYYVSMTEKKVSDIPEIKTLITTLTSDSNNSKASIAIELESQKNRKRTTDE
                     IEKEIIDRVATVPDCKINVSQNSSVMGGAGGADFTLEMKGPDLDVLKILGKEAEKEFS
                     SIKGFRNVETSLTDTTQEAQFTIDKHKAQEYGVNTAEIAGMLRTAINGDSVTTATIDD
                     YKVDVNLKFKADTIDSLEDIKQLKVNSATGKEVPLGAFSDIKMADGLQSISRTDGDFS
                     VNITATLDNLDAGTATKLALEKTNKMVIPKDYSIGVGGETEMMNESMASLGFSMVIAI
                     ALVYMVMVAQFESFSKPFIIMFCVPFAFVGVVLSLLVSGQSLSTVGMLGIILLIGIVV
                     NNGIVLIDYIEQLRKTNRNNDLIGLVSIGCAARLRPVLMTTATTILGMLPTALSLGEG
                     GETMQPLAIVIMGGLTVSTLITLVLIPTIYLIFDKWENKFSDKMPKIFGKITDKIGSI
                     KRKIIKKPKLKAKV"
     gene            12865..14163
                     /locus_tag="OE968_002109"
     CDS             12865..14163
                     /locus_tag="OE968_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TolC family protein"
                     /protein_id="HCP7219388.1"
                     /translation="MSKIVAISCGVGIITANLIPVYADNNTSSINKVDNSILSDSNKR
                     TSEKEILTAREAVSAALKNSEKLKMKSEEIKMLKEKLEVQDEFDSFTGSDNSFPYDQI
                     GLLKNQSEQAKGFMEDQIANDITNKFNDLVSRENELDKIKNNLEIKTKEIKDMKLKKD
                     LGLVTSLETESAELELQTLQNTQKAKLQELKNNQDYFKLLTNIDLNNYQLDKEYRFES
                     FRVGGSVDSYMEGKVNEYLKYDQLILERTEESFNDKDENKADLPDRPNLTRPVAPTKP
                     EQGNLTDDEYKVLMDKYEKDYDRYKKEVEAYNLERQTYAAGLTTYANYLQQKFNTENG
                     LVTLEDSKKALKKGLIDSYAQLLALEDTIQITKKQLDLSEKQLKNTKLRYDLGLITLT
                     DYKKQVVSNEDAKNSYDTLIVNYNSLKNGIEKPWILNTGK"
     gene            complement(14452..14697)
                     /locus_tag="OE968_002110"
     CDS             complement(14452..14697)
                     /locus_tag="OE968_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HCP7219389.1"
                     /translation="MTKCPKCGKEVSSRPGSICPRCGFKVADESLKIRCPEPSCRALV
                     SRKLDYCPKCGCKLRGYNISEFVNMVRCKIDETFDKK"
     gene            complement(14911..17538)
                     /locus_tag="OE968_002111"
     CDS             complement(14911..17538)
                     /locus_tag="OE968_002111"
                     /EC_number="2.7.9.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate, phosphate dikinase"
                     /protein_id="HCP7219390.1"
                     /translation="METKYVYSFGEGSKDMKSLLGGKGANLAEMTKIGLPVPPGFTIT
                     TEACNDYYVNNESIRAEIIKEIEEHLATLEKDLNKTLGCNKNPLLVSVRSGAVFSMPG
                     MMDTILNLGLNDNSVVGLAEATQNERFAYDSYRRFIQMFSDVAMEVPKYKFENVLDRV
                     KEAKGYTVDTELTTDDLKEIVKEFKAIYKKEIKNDFPQDPKEQLMLAIEAVFRSWNNP
                     RAIVYRKLNDIAHNLGTAVNIQSMVFGNMGETSGTGVAFTRNPATGENKLFGEFLMNA
                     QGEDVVAGIRTPQNISTLADVMPAVFDEFVKITHILEGHYKDMQDIEFTIENERLYIL
                     QTRNGKRTAAAAINVAVDLVEAGIIDEKEAIMRIEPNQLDQLLHPKFEDKALKEAKVI
                     AKGLPASPGAASGKVYFNADDVVKANEKGEKVVLVRLETSPEDIEGMVKAEGILTARG
                     GMTSHAAVVARGMGKCCVAGCGEIKVDEFNKEIRALDDVVIKEGEYISIDGSTGNVYL
                     GDVKKTEVSLTGNFEKLMNWVDKHKCMMVRTNADNPRDARAAIEFGAEGIGLCRTEHM
                     FFDEARLPAVREMILSNTVEQREKALEKILPMQREDFVELFKVMDGKPVNIRLLDPPL
                     HEFLPHDDETIEELSKSMGIKVSDIKKRIVDLDEFNPMLGHRGCRLAITYPEICVMQS
                     KAIIQGAIEAIKAGVKVSPEIMVPLVGEVNELKIIRKMIVETVDAIIKEEGIEVPYTV
                     GTMIEIPRACLTADEIAQEADFFSFGTNDLTQMAFGYSRDDAGKFLGQYVDEEILEKD
                     PFQVLDQNGVGKLVKMGAKLGREVKPELKLGICGEHGGEPSSVEFCYSVGLNYVSCSP
                     FRVPIARLAAAQASIKNPR"
     gene            complement(17599..18441)
                     /locus_tag="OE968_002112"
     CDS             complement(17599..18441)
                     /locus_tag="OE968_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase/pyrophosphorylase"
                     /protein_id="HCP7219391.1"
                     /translation="MLVKNLIIYAVSDSVGETAQQVAKACMSQFYVNETYEIKRFPYM
                     INKGVLLETLENAKAENALIVYTLVDEELCSIVERYCEREGLSCIDLMTDILREISKR
                     TGRKPKREAGIIRKLDESYFKRVEAIEFAVKYDDGKDPRGVLQADIILVGISRTSKTP
                     LSMYLANKNIKVANVPLVPEIPIPKEVFEIDTKKIIGLTNSPEKLNEIRTQRLKALGL
                     SSKANYANLERILQELDYSEEIMKRIGCPVINVSNKAIEETAGIILDIMKENGLKIYK
                     EIEI"
     gene            complement(18448..19086)
                     /locus_tag="OE968_002113"
     CDS             complement(18448..19086)
                     /locus_tag="OE968_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCP7219392.1"
                     /translation="MIIIQLNERQLKIIDIVKENEPITSESIASSLNVTRATLRSDLA
                     ILTMTGILDARPKVGYFYSGVSEINLIGKSVKEKTVEDIMSMPVLAKKDESIYDVIVT
                     MFLSDVGSIVIIDENEELCGVVSRKDLLKATIGGSDINKMPIGMIMTRTPNVVTLTKG
                     ASVLLASRKIIEHEVDSIPIVEYKGEDKNHMRVVGRISKTNITKLFLEIVDN"
     gene            complement(19522..20814)
                     /locus_tag="OE968_002114"
     CDS             complement(19522..20814)
                     /locus_tag="OE968_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HCP7219393.1"
                     /translation="MLDLNRKLAKLEEEGKKIKVALIGAGHMGNGMVSQMANMKGIEA
                     SIVVDINLELAHKAFTDAGIDEEIIDNVTNEKDAEIKLQEGKVLTCNDFLVACKTKSI
                     DVVIDATGGIAIGAEIALNSILNKKHIVMLNAETDCVVGPILKKLADDAGVIFTGSAG
                     DEPGAVMELFDFADAMGFEVRVIGKGKNNKLDLDCNPDTVREEAERKGASPHMIASFK
                     EGTKTMVEMALMCNATGFVPDVRGGHGIEATVNEVPKKYALKSEGGVLDNYGVVDFVN
                     GIAPGVFVVVAHKLKAVNDELKYLSMGDGPNYILYRPYHLCSLETPLSAAMAVLDHKA
                     TIVPKAGLVAEVMTIAKKDLKKGEFMDGYGAYTCYGTIEKYDVAKAMNAVPIGLISKK
                     TKVVKDIKKGEVITYDMVEIEKDTTLYHLRQLQEKIFG"
     gene            complement(20851..21207)
                     /locus_tag="OE968_002115"
     CDS             complement(20851..21207)
                     /locus_tag="OE968_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HCP7219394.1"
                     /translation="MKYEVKISGIGSLVKELMDESNCLIIYDETINDDDLKDISVIHS
                     IATLKSDVEIGDTLTIGNRDYCIVSVGDIAQKTLREIGHCTIKFDGKCEVNLPGEIHV
                     EIGNPDITIGDLITIS"
     gene            complement(21242..21601)
                     /locus_tag="OE968_002116"
     CDS             complement(21242..21601)
                     /locus_tag="OE968_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219395.1"
                     /translation="MKLLVILFVAYILNTIFIMKQNKLYFKTLNRAKKKGDIVSTGKK
                     KSYFSKGSIAIISSDSDGFIKFGEILKGRTVMAKFKEIEEIEGLDIYSAEQKFKDEES
                     IVQAIKFIKEKINVSFN"
     gene            complement(21670..23643)
                     /locus_tag="OE968_002117"
     CDS             complement(21670..23643)
                     /locus_tag="OE968_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HCP7219396.1"
                     /translation="MSVTEKIPSIDRKIFKILIMCSKKEFVSINSIANELNVTTRSVR
                     TYIKQLNKDLGNDIAVIKYIKGQGYKLEIKDEQILNKIIDMNRKNVFSLNSKEDRVEF
                     ILNYLIELDGFITLDSLADEMCVGRTTLVNDFQYVEKVLASYNLNLIKKQNTGMKLNG
                     NELDIRLFILNQLYKNSRKDFSNSKYFKGIKKEEIINLEEKLLTLFKKNNFYVTDEML
                     REVINYIVVLVYRVKEEKKVKDYDVKFDLLKSYDEYFIAREIKHIISGMFECTLNDEE
                     IIYLTIPLVSGNAPASECALNSSRISKNIDELMENIFNQIYVDMGIFINEDELRVGLG
                     YHLSFTLNRLLFNIKLKNVLLEEIKQNYILPFKLAQIAGKVIEKKYNLEVSEDEIGYI
                     AIHFSGYLERNSSRFYSIKKIAIICSTGLGTAKLLKIRVEKLIGNNPKIDTLSSFNLR
                     NINLDEYDIVFTTIDLDTSNINTIVLKINTIFDENKLREQLKTVLCLREGNIDTTNST
                     NLLINNLLDEDKFMILNEKTILASLEKMMDHLMDLGCIDDKFRKNIVNREEKSPTVFD
                     KGLLFPHSVNEKSDKFLMAVGILEEPIEYANRSIKIILMTMFPCENKIDSDLLVKIYE
                     EVLKIGQDVKLTNKISKCRTFLEFKKVLLKNLI"
     gene            complement(23865..24878)
                     /locus_tag="OE968_002118"
     CDS             complement(23865..24878)
                     /locus_tag="OE968_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HCP7219397.1"
                     /translation="MEENKILKIEKGTSGWGGPLYIKKEGNRNKILSMTAGGIHEVTL
                     KIKELLGCEIVDGFKTGVSDEEVAVVIIDCGGTARCGVYPKKKIPTINVNPVGKTGPL
                     AKFITEEYYVSDVNPNCISVVDGEDMPQKSQENKSENKSSIRKPDNYDEVKSKAQGEY
                     AKKNIILSIGQGAGQVVSKFYDAGRDTIQMVMNNVIPFMAFVSMLMGIILASGLGDWI
                     ARVISPLAGNIGGLLIISVICTLPFLSPILGPGAVIAQVVGTLVGTQIGLGAIPAYLA
                     LPALFAINGQAGCDFVPVGLSLGEAEPETVEYGVPALFYSRLITGPIAVIIAYGVAVF
                     ALR"
     gene            complement(24891..25436)
                     /locus_tag="OE968_002119"
     CDS             complement(24891..25436)
                     /locus_tag="OE968_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HCP7219398.1"
                     /translation="MENVITGLSKGAEWFIGLFQKGGEQFIGLVSGTLPTLIVLMVAI
                     NSLIKIIGEERVNNWASKLGKNSFTRYILLPLVSVFFLGNPMCYTFGRFLKEEHKAGF
                     YDAAVSFVHPITGLFPHANAGELFVWLGISAGLTTLGKETTTLALWYFIVGLIVIFIR
                     GIVTEKMYAFLTRKNRATNKA"
BASE COUNT         8778 a         4259 c         3261 g         9321 t
ORIGIN      
        1 attcattcta taaagcatta aatcttctag tacatctttc atatcgaagt acacatcttc
       61 taataaataa aaatagcctt cctctatatc tttcaattta tctatagtat ccattttttt
      121 acttatatct ttcataattt ctaaattttg tatatttaca tctatgattg ttaataagta
      181 cattctcaca gtttttatta tttcaacaga aaaatctaca atattataat ttccttcttt
      241 tttatataat gactccttaa atttgttaaa acaattatct aaattagaat ttatatcgtt
      301 aaatggtggt cttattatgt cacgtattat taaaagattt tgtatatcta cattatttgt
      361 gattgcctca tccaaaataa ataaattata tgcatcattt aatgggtcat gggcatctcc
      421 actaaactct aagttaacaa attcaagtaa atttttcaat gatatatagt tcatacatct
      481 cataccacaa tttatatatt tttcttttat atctacaaat aaatctctaa tgttatttac
      541 aaaccttgga tggttatttt ttttagcact tctcatatct gtgttattga aacatgtcaa
      601 atccaaatta ccaaaagtat atattccttt aatatcagaa aatatgccaa gccatttttt
      661 aaactttctc atgacctctt cataacttgg tgcactcttc aattcttcag aagatatatg
      721 tgttaattct tgtatatgag gatacaactc ctcattactt actggtctta ttaaagattt
      781 aaatttatca atattttttg ttttttcatc atacataact gctccgattg caattatatc
      841 agaattaaat actgctcttt ttgatttaga atttggcata ttcatttcaa aatctatata
      901 tactcttttc aatataaaca ccctttccaa ttgtttatag tgattctttt taactatttt
      961 tattcaaaat tttctaagaa agaatgtttc tccccatctt tttgccaacc aagtactgaa
     1021 tcaagattta cattttctgc cgccttaaat atagattttt ctacattttt aaaatttgat
     1081 tctaagctct ttattaagtc ttttatctca tatcttttat tacctgtttt tttagcagca
     1141 accatacatg cacaatttaa tggccatata ccactatttt gaataaatct tataatatgt
     1201 tcttctctta tataataaag tggtcttata atttttatac cttcaaaatt agtagaatta
     1261 agtttaggaa gcattgtttt aaaatttcca gcacacaata aattaagcat tgttgtctct
     1321 attacatcgt cataatgatg acctaatgca agtttgttac accctaattc ttctgccttt
     1381 gaatataatg ctcctctcct cattcttgca cacatatagc atggataatc ttttgctatt
     1441 tcatctgcta tctcaaatat ccttgaatca aataaatgta ttggtatatt tagatactca
     1501 caattatcta taagtaattg tcttatattt gcatgatatc cagggtccat agcaataaat
     1561 tcaacatcaa aattaacttg tccatgtttt tttaactctt gaaacatttt agccataaga
     1621 atactgtctt ttccaccaga aatcgctaca gctatcttat caccttcttc aaccaattta
     1681 taatctctta ttgccttcat aaacttagac cataaatttt tcctatattt ttttattata
     1741 cttttttcta tatctcttac tggaagtctt tcctcaaaag gaactataat ttcacagcct
     1801 tttcctgata gttcactcat ctaatcacct cgtatattta tgttaataat attttacaaa
     1861 aaagtctacc ttcatccaca aaatactata atttttactt taattttact aaataattta
     1921 tagtttacaa taacacataa acttataata acataaataa cctctttctt ttattatctt
     1981 ttttattttt ctcatttaat attttattat tagtaacgat ttttaaatga ttgaatatta
     2041 tacactagat agagttacct atctatttac aacaaggagg ttttcatctt ggaaaataag
     2101 actagagata tcaaaaaaaa ttgtggtcca tctttggcta gaccatacat taataatcaa
     2161 attttcacag aaatgtactg cctttctgat gcattaaaat ttggaactat atttccagaa
     2221 ctaaacttac tagagtctga aatgtacaac aaagaattat atgctaagcc aaaaaaatat
     2281 agaggaggta gaagataatg aaagactcat ctagagctga acttatgaga aaagttcagg
     2341 aaacatcttt tgcatgtgtt gatatgaact tatatttaga caatcaccct gatgataaaa
     2401 atgctatcaa cacttataat tcattatgta atcaatttgc gcaagctaga tatgcttacg
     2461 aaaataaata cggtccttta actaactttg ggtatgctcc aagtagatgc ccttggcaat
     2521 gggctgacca accttggcct tgggacagag aatttaatta ttagacatca agtattggag
     2581 gattgaaaat tcatgtggat atatcagaaa actatacaac acccagttaa tataaaaact
     2641 tgtgacccta gaatggctaa atttcttata actcaatttg gtgggccaaa tggagaactt
     2701 gctgcatctt taagatattt aagccaaaga tatacaatgc ctactggtaa tatgcgtgca
     2761 cttttaacag atattggtac agaagaacta gctcacgttg agcttatatg tactatggtt
     2821 tatcagttaa cttctgatgc aagcccagaa gagttaaaag ctgcaggtct tggttcaaac
     2881 tatgctcaaa atggatatgg aatttatcca acagattcaa atggtgttcc atttgatgta
     2941 agacctatag cagttatgtc aaatcccgta accgatttac atgaggatat ggcagctgaa
     3001 caaaaagcac ttgcaactta ttatcaactt ataaacctaa cagatgacgt tgatgttata
     3061 gatgtattaa aattcttggg tcaaagagaa ataattcatt atcaaagatt tggtgaagcc
     3121 ttaatggatg cttacgagtt agaagaatct caaaaaatgt tctaaaattt ttatttgtat
     3181 aactattatt atttgataat ttataattta ctgttgtgtt aaaatttata aaaaatataa
     3241 atataattta ttttctataa acagagaaaa taaataaaaa gcaggtatca atcaaatagt
     3301 aacatgtatt atactataca ttactatcaa tattgtacct gctttcatat tataagcaat
     3361 aaagaaaaat ctatttatta ggttttataa taaaaacaat tataaaactc ttcttgcatt
     3421 tacatatcta cttgaatagt agctactatt tatattagat attgttactt tttttgatga
     3481 acctgaagat gcatgtatca tatctccatt tcctatgtat attccaacat gacttacaga
     3541 accattattt gaaccttgtg tatcaaagaa tactaaatct ccacttctaa ggtctcctct
     3601 atttacatat gttccatact tactttggtc tctagatact cttggtatac taactcctac
     3661 agattttttc ataacgtact gcgtgaatcc agaacagtca aaactatttg gaccttctgc
     3721 tccccataca tatggttttc caagtagtgt ctttgcaaaa cttattacac tatcagctcc
     3781 ttgacttgga gaattagtcg aataagatgg aattgaagta tcaacagaac ctttttcagc
     3841 aaggtattga cttgacacat atccagtttg attgccataa cttatttttg tccatcctcc
     3901 actttcagaa atacttccaa cctcagtacc ataacttaat gtagctattt tagaatgact
     3961 tgtacctggt cctgttctaa cgttcaatga ctttgctgtt acaacctttg taccctttac
     4021 aaggtcattt gaactgtttt cagcattttc atttgtagag tcatttacac tagttcctaa
     4081 atatttactt gaaacataac ctactctacc attagaactt atttttgacc atccatttga
     4141 ctcagatatg tatccgactt cagtcccata tcctagtgtt gatattttag aactacttgt
     4201 acttggtcct gttctaaaat ttaatccttt tgctgttaca acttttgtcg acttaactga
     4261 agtatcacta ctttcattgc tacttccaag gctatttatt gctacataat ttccatgcac
     4321 ataacctgtg tttccattat atttaacttt tacccaagaa ccttcttttc ctacgtactc
     4381 aactttatca cctttgtaaa gtttccccat tgattcatgg tttgtacctg gtccttttct
     4441 aaaatttacc gcattccctg ttattgttct gctttctata ctcacactct ctacttcaga
     4501 ctcattagca tatgctaaat tccccatagt aggcattatt atcgcagttg ccattatact
     4561 ggctgctatt ctcttttgat taaaattcat aactttccac tcatctcctc ttttctacta
     4621 tctttatttc acttcaaaat ataaaagaaa taattgacac tatcaaaata tcaattattt
     4681 cttttatatt aatattatta caaatttgta actatttgtc tatagtaata tttgcttacc
     4741 ataaattacc atgtataaat tttaatcttt aatagcctgt aatttagtaa tatagccatc
     4801 ttttaccttt tttaaaaatg gctatatttt ttaacttttt tgtaactttt taaaatccag
     4861 ttgagccaaa cccacctttt cctctttcgg agtcacttaa ttcttttact tcttctatgt
     4921 taatatcata gataggtttt actatcattt gagcaatttt catatgcttt tcaaccttaa
     4981 aatcattttt accatgattt attaatataa ttttaagctc tcctctgtat ccttcgtcaa
     5041 tagttcctgg tgtatttaat acagtaacag aatgctttaa ggcaagccca cttctaggtc
     5101 ttacctgcgc ttctgtcata gtaggaagct ctatacatat cccagttttg ataagtttag
     5161 tctctccagg aggtattaca acctcttcta tagaatacaa atccatacca gcatcacctt
     5221 tgtgagcaaa attaggtatt atagcatcat catttaattt ttttactttt aaattgtaca
     5281 tcttatatct cctttcaact ttctataaat attataactt aaatttcgac ctcttgaagt
     5341 tttttatttt tttgtggtaa tataattatt agtgttttaa aggaggattt tttatgaaac
     5401 ttgtacttgc tgagaaacca tctgtggcaa aaactatagc atcattttta ggtgcaaaga
     5461 ccagacaaga tggttacttt gaaggaaatg attatataat tacttatgca gttggacact
     5521 tagtatcatt atatgatatg aaggattatg ataaagataa atactctggc tcttggaaaa
     5581 tgaacaattt cccatttgtt cctgaggata agtttaaatt taagattgat agttctaaaa
     5641 ctaaacaatt caacactgta aaaaagcttt tgaatagaaa agatgtagaa tatgtaataa
     5701 atgccactga taatgaccga gaaggagaac ttatagcatt tttaatattt ttactggcaa
     5761 aaaataaaaa accagtaaaa agaatcttgg taaatgaatg gacaccagaa gatattacaa
     5821 gaggtataaa aaacctaaaa gatgaagatg aaatgagaaa tcttcaagct gctggatata
     5881 ctaggcttat tactgactgg ttgattggaa taaatttcac ttctgttgct acattgaaat
     5941 acggaaatgg gaaactatta aacataggta gggtaattct tccaacagtt aaattagtct
     6001 atgatagaga tatggaaata ctaaactttg ttcctaaaac ttattatgaa atagaagggc
     6061 attttaaagc tgaagctggt gaatataaag gtaaatatgt taagggtaaa gaaagtaaat
     6121 ttgatacact tgaagatgca aataaaatta tagcttcaat tacatctgaa actggtaaaa
     6181 tactagataa aaaagttact atgtcaaagg aatatgcacc aaaacttttt agtttgacat
     6241 cacttcaagg atatataact tctaagtatt ccaattttac atctgataag gttttaaatg
     6301 tctgtcaatc tctctatgag ggtaatggta agggtggata cataacttac cctagaactg
     6361 attccatttt cttagaagaa agtttggctt caaaagcttc tcaaacttta gataaattaa
     6421 aggttggtct tgaatatgaa aataaaatta aattttctaa aactaaaaga gtttttgatt
     6481 cttctaaagt agactcccat agtgctataa ttccaactta tataattcca aaaagtttat
     6541 ctaaggatga acaattagtt tatgatgcca taaaagatag atttgtagca aactttatgc
     6601 ctcctgctga atatgagaat acagaaatta agactgaagt agataattgt actttcttaa
     6661 caaaaggtaa ggtgcttaaa tcaaaaggat accttgaggt atataataag gaagaaaaaa
     6721 acgatttact tccacttgta aataaagatg atgttgtaga tgtgttagaa ataaaaccat
     6781 taactaagca aactactcca cctaaaccgt atactgagga cacactttta aaggctatga
     6841 aaaattgtgg taaaaatgtg cctgaagaag atacaacagt gctatctgga tattcgattg
     6901 gaacatcagc cacacgtgct gatgtgttaa agaagataag tcaagtgggc tatgtaaaga
     6961 aaaaaggtaa atcttattct ataacagacc ttgggaaaaa tttagttgaa atttttcctg
     7021 ttaaagactt atttgatgta gattatactg gaaaacttga aaaaagttta agcgatattc
     7081 aaaaaggaaa gtatacaaga aaagaatatc ttactaatat cattagtttt atatatcaaa
     7141 atgtcaatat tataaaacaa gatgcttcaa aaaatataaa cacagaagca tatactttcg
     7201 attcaaaaac taaaaaattt actaaaacaa aagaaaaaaa acagaaaaaa gatgtaacta
     7261 atactgaaaa agaagttgct atatcaaagg attctaataa caaaaaagaa gttaaaaatg
     7321 gtgatgaaaa tcaatctctt ggcaaatgcc ccatttgtca aggtgatgta ctagaatttg
     7381 acaaaggctt tgcttgtaaa aatcataaag aatgtaaatt tgttatttgg aaaaatgata
     7441 agtatttaag tctttataaa aagaaagtta acaaaacaat ggtcaaaaat attttaaaaa
     7501 aaggtgaaac taaagtaaaa tctttaactg ctaaaaacgg taataaattt gatgctacat
     7561 taaaatatga taaaaatcca gatactggct atttcaattg gaaaatagag tttgacaact
     7621 aaatattcat aagaaaagaa atagcagtag tataataatc tatattatat tactgctatt
     7681 tcttttctta tgaagtttca acttttttaa tagtgacttt tacaatcaca ctctaaccta
     7741 atttctttac tatttctgat aactttaatg tatgttcatc taataaagtt agttcctctt
     7801 cagaaagatt agataatttt tttactagag attctttgag aatagctttt actgcatcaa
     7861 ataatttaaa tgctttatct gttaattcaa ccctaagaat ccttctatct tttgggtcag
     7921 gaaatttatt gactaaacca tgttccacta atctgtcaat aatcggagtc atatttgatt
     7981 ttaaaattcc taaattagaa gctatttgag aaattgatga tgaatttgat gtcataagat
     8041 aaagaattac cttagcatgt gatggagcca ttggacattc ttcaaaataa gctttcatta
     8101 tatcagagtt attttgaaac ttttttaaca aatcgctttc tttaaatata ttattttcaa
     8161 gcacaaataa aaaatctaaa aaagagtccg ctattttaag tatattgttg ttatccatat
     8221 ttgtaacatc ccttcaatag ataatataat aaaacattgt tgtttaatat agtataaatt
     8281 ataaactatt aataaattta aaacaagaaa aagttattga ctcataataa ttataaattt
     8341 ataatcaaat tagagaatta taaattgcca ataaagggaa gttttttaat tagtctaaaa
     8401 ctaaacttaa attataagac actttaaatt ctacaacaag ctagtgtgca atatataata
     8461 ggaggagata tgaaaagata tttaatagtt ttcttaatgt gtagttcact gtttttagtt
     8521 ggatgtggaa aaacagaaga atctgaacct gagaaaccaa tagcagtttc tgttcaaaaa
     8581 gcaataggtg gagaaattga aaacacaaat tctttctcag gaactacaaa ggttaaagat
     8641 gaaacagctg ttactgcaca gactgttggc acagttcaag aagtgtatgt aaaacttggg
     8701 caaaatgtaa gaaaaggaga tgaattattg agtataagca gtccagagct agaaaatagt
     8761 gtaaagcaaa gtaaagcctc actagattta gcaaaagcaa gttattcaag tgccactggt
     8821 ggttcattag aggcacaagt aaatcaggca aaaacagctc ttgacaatgc aaagattcaa
     8881 tatgaggagt ctcaaagaaa ttatgacaat aataagattc tttatgaaca ggaagtcatt
     8941 agtttagacc aatttaaaaa aatagaattt tctttagagc aaacaaaaca acagttagat
     9001 tctgctcaaa gagcatacga tacagcaact tcaaaaagta tacctcaagc taaagcactt
     9061 gctaaaaaac agcttgacca agctcaagta tcatataatt tagcaatgag taatttagac
     9121 aaattaacat taacatctcc agtagatggt acaataacag ctaaaaactt tgattcaaag
     9181 gaaatgataa cacaatcaca accagctttt attatttcta atcctaatat actagaagtt
     9241 gatttaaatg tagcagaatc agatataggt aaatttaaga aagatggaaa tgtagatgtt
     9301 ataattgaag accaaaggat tttaggaaaa atagattatg taccttcagt agttgaccct
     9361 cagacatctt tatatcctgt taaagtactt gtaaataata caaacaacaa atttaaggca
     9421 ggtatgtctg ctcaagtaaa cttaagtgtt gaaaaagaaa atggtgctgt tacagtacct
     9481 aaaaaagcaa tatttgaaga aaatggtaaa aaatatgtat acatagcaac aaaagacaat
     9541 atagcaaaga aacacttggt tcaaactgga attgtaacag aggataaaat agaaattaaa
     9601 agtggtgtaa gtgataaaga tacagtgatt atcggaggga taagtcttat ttctgacgga
     9661 actaagatat ttcctgtaga aaaggagaag tagactatga atttaacaca gacttccgtt
     9721 aaacgtcctc tcacaatcat aatggtcttt ttagtattaa tagtttttgg tggtattgga
     9781 tataaaaaaa tgtcaataaa tctaatgcct gatatagaaa taccagttgt aatggtcatg
     9841 actacttgga caggtgctgg tcctcaagac gttgatgaac aagttagtca aaaagttgat
     9901 gaaagtttat ctgccgtttc aaatgtaaaa tctactatat caagttcaca agaaagtgtt
     9961 tctatggtag ttgctcagtt tgaatttgga actaatttgg atgaaataat gaatgatgtt
    10021 aggtctaaag ttgatgcatt acagaccagc ctcccagatg atgcagctaa accaacagtt
    10081 ttaaagctgg atatgaatgc acaggctata ggtcaacttg tcatatctgg aggaaatgaa
    10141 aatagttcac aagccttaag aaaatacgct gaagatgtaa ttcagcctaa aatagaatcc
    10201 atagatggtg ttacttcagc agaccttaaa ggtggagaaa aagcacaggt taatgtaata
    10261 gctgacccag ctgttctttc aaattatgga gttagtttat ccactataaa aggtgtctta
    10321 tcctctagta ataaaacatt cccttatggt tcaattactc aaggtgagga taaaatagtt
    10381 ttaagagcga ttgataaatt agaatcccta gatgatataa aacagattca aattcctgta
    10441 aaaggaggaa atacagttag attagataat ctttgtagtg tagattatgg atatgcagac
    10501 aaagatagta tttatagata caatggaaaa gacagtttgg taatagatat ttctaaacaa
    10561 caagatgcca acactgtaaa agttatgcag agtgcataca aatacgtaga tgaattgaat
    10621 aaggaaaatc ctcaatttaa aattaaaatt gctaatgata caagttcata cataagtgaa
    10681 tcaataaaca gtgtaatgag caacttgctt ataagtgctg ttatcgcatt tattgtaata
    10741 tttgctttcc taaaaagtgt aagagcttca ctagttgttg cagttgcaat accaatttct
    10801 ataataggtg ctatagcaat tctctacttt actggtgaaa gtttaaatct tattactgca
    10861 agttcattgg taatttcagt tggtatggtt gttgataatg ctacagttgt aattgaaaat
    10921 atatttaaat ataggaaaag tggtagattg agtcttgatg attgtgctat tgagggaaca
    10981 agaactgtaa caaatgcaat acttgcatca acattgacca caatagcaat attcttacct
    11041 atcatgttta cagaaggtat agctaaaata acttttgggg cattaggtaa aacactaata
    11101 gcttcactag cattctcctt tataggtgca attacactcg ttcctagtgt atttgcaaaa
    11161 ttaagcagag gaaaaaatag tcaaaagatg caagaaaaag atagtcctat atttgataag
    11221 gtaagtgaag catataaaaa attattaagt gtatgtttga gacatcaacg cttagttgta
    11281 atatcaagtt tacttatttt tgtagcttcc ttatttggaa tgggatttat aggtatggac
    11341 tttatgcctg cagcagacaa gggtgaatta tctatttcta tagaacttcc aaaaggtctt
    11401 agcctagaat ccaatgatta ctatgtatct atgactgaga aaaaagtctc agatattcca
    11461 gaaattaaaa ctttaataac aactttgaca tcagattcaa ataatagtaa agcaagtata
    11521 gcaattgaat tagaatctca aaaaaataga aaaagaacta ctgatgaaat agaaaaagag
    11581 ataattgata gagtggctac tgtaccagat tgtaaaataa atgtaagtca aaacagtagt
    11641 gttatgggtg gagctggagg agcagacttc acattagaaa tgaaaggtcc tgatttagat
    11701 gtattaaaaa tactgggaaa agaagctgaa aaagaattta gctctataaa aggatttaga
    11761 aatgttgaaa cttctcttac agatacaaca caagaagctc aatttactat agataaacat
    11821 aaggctcaag aatatggtgt aaataccgct gaaattgcag gcatgttacg tacagcaata
    11881 aatggtgact ccgtaaccac tgctactatt gatgattaca aagtggatgt aaacctaaaa
    11941 tttaaagcag atactattga tagcttagaa gatataaagc aactaaaagt aaactctgca
    12001 actggaaaag aagttcctct tggtgccttt tcagatataa aaatggcaga tggtctacaa
    12061 tctatatcta ggactgatgg agatttttct gtaaatataa ctgctacact tgacaattta
    12121 gatgctggta ctgctacaaa actagcacta gaaaaaacga ataaaatggt aattcctaaa
    12181 gattactcta taggtgttgg tggtgaaaca gaaatgatga atgaatctat ggcaagtctt
    12241 ggattttcaa tggtcatagc tatagcatta gtttatatgg taatggtagc tcagtttgaa
    12301 tcatttagta aaccatttat aatcatgttc tgtgttccat ttgcattcgt tggagttgtg
    12361 ctttcgcttc tagttagtgg tcaaagttta agtactgtcg gtatgctagg tataatctta
    12421 cttatcggta ttgttgttaa taatggtata gttcttattg actacataga gcaacttaga
    12481 aaaacaaatc gtaacaatga tttaattggt ttggtttcaa ttggttgtgc agcaagatta
    12541 agaccagtct taatgactac agcaacaaca attttaggta tgttgccaac agcactatct
    12601 cttggtgaag gtggagaaac tatgcaacca ctagccatag ttataatggg tggtctaact
    12661 gtatctacac ttataacttt ggtgcttata cctactatat acttaatatt tgataaatgg
    12721 gaaaataagt tttcagacaa aatgcctaaa atatttggta agataacaga taaaatagga
    12781 agtataaaac gtaaaataat aaagaaacca aaattgaaag ctaaagttta aatagaatgg
    12841 agggtgattg tattgaataa aaaaatgagc aaaatagttg caattagctg tggtgttggt
    12901 ataataactg ccaatttaat cccagtttac gcagataata atacttcttc tataaacaaa
    12961 gttgataatt ctattttaag tgactcaaat aaaagaacat ctgaaaagga aattttgact
    13021 gctagagaag ctgttagtgc tgcacttaaa aatagtgaaa aattaaaaat gaaatcagaa
    13081 gaaataaaaa tgttaaaaga aaagttagaa gtacaagatg agtttgatag ttttactgga
    13141 agtgacaact cgtttccata cgaccaaatt ggacttctta aaaatcaaag tgaacaggct
    13201 aaaggcttta tggaggacca aatagcaaat gatattacta ataaatttaa cgatttagtt
    13261 tcaagagaaa atgagctaga taaaataaaa aacaatcttg aaataaaaac taaagaaatt
    13321 aaagatatga aattaaaaaa agatttaggg ttagtaacat ctttagaaac tgaatcagct
    13381 gaacttgaac ttcaaacact acaaaatact caaaaagcta aacttcaaga actaaaaaac
    13441 aatcaagact attttaagtt attaactaat atagatttaa ataattatca attggataaa
    13501 gaatatagat ttgaatcttt tagagtaggt ggctcagttg attcatatat ggaaggtaag
    13561 gttaatgaat atttaaaata cgaccaattg attttagaac gtacagaaga aagctttaat
    13621 gataaagatg agaacaaagc agatttacca gatagaccta accttacaag accagttgct
    13681 cctacaaaac cagagcaagg taacctaact gatgatgaat acaaggttct tatggataag
    13741 tatgaaaaag attatgatag atataaaaaa gaagttgaag catacaatct tgaaagacag
    13801 acttatgctg ctggccttac tacttatgca aattatcttc aacaaaaatt taatactgaa
    13861 aatggtctag taacattaga agacagtaaa aaagctctta aaaaagggtt aattgatagc
    13921 tatgctcaat tacttgcttt agaagataca attcagatta ctaaaaaaca acttgattta
    13981 tcagaaaaac aattaaaaaa tactaaatta agatatgatt taggattaat tactctaact
    14041 gattataaaa aacaagtggt aagtaatgaa gatgctaaaa atagctatga cactcttatt
    14101 gtgaattata actcactaaa aaatggtata gaaaaacctt ggatacttaa tactggaaaa
    14161 taattctggt aaatagaaag attactttaa catacgtttg attaaaaaat agttatgcat
    14221 actcgtggct ttagtcatgg aagattcaga aggcaaataa tagaaataga ttagtaaaaa
    14281 tatatttact tataaaactg tatactttta tagaggctat ctcaaaatag agataagcct
    14341 cttttttatt gtttaaatta taaaaatata tttgattcca tacaaaaaga gtgccttctg
    14401 aactaaaaag ttcattttga gacaccctca aaagcttaac tctaaattta attatttttt
    14461 atcaaatgtt tcatctattt tacatctcac catgttaaca aattcagaaa tattatatcc
    14521 tctaagtttg catccacatt taggacaata atccagtttc ctagatacca aagccctaca
    14581 actaggttct ggacatctta tttttagact ctcatctgct actttaaatc cacatcgtgg
    14641 gcatatacta cctggacgtg atgatacttc ctttccacat ttaggacact ttgtcaactt
    14701 tatcccctcc agtaaactca atttaattga tagttgaaat ttctctctac aataatatat
    14761 gcaatataat taaatacgtt tcacttacaa ctatataagt taaattttta taataaaaat
    14821 cccctatatt caatttacaa atacttaatt tgatacattg aacaataggg gattttattt
    14881 ttatttagtt acatattttg cagtctatta ttatctagga ttttttatag atgcttgagc
    14941 tgctgcaagt ctagcaattg gcactctaaa tggtgaacaa gatacatagt taagtcctac
    15001 actataacag aactctactg aagatggttc tcctccatgc tctccacata ttcctagttt
    15061 taattctggt ttaacttctc tacctaattt agctcccatc ttaactaact taccaacacc
    15121 attttggtct agtacttgga atgggtcttt ttctaatatt tcttcatcta catattgacc
    15181 taagaattta ccagcatcat ctcttgaata tccaaatgcc atttgagtta agtcattagt
    15241 accaaaactg aagaagtctg cttcttgtgc tatttcatca gcagttaaac aagctctagg
    15301 tatttctatc atagtaccta cagtataagg aacttctata ccttcttctt ttattatagc
    15361 gtcaacagtt tctactatca tttttcttat tatttttaac tcatttactt ctccaactaa
    15421 tggaaccatt atctctggag aaactttaac acctgctttg attgcttcta tagcaccttg
    15481 tattatagct ttagattgca ttacacatat ttcaggataa gttattgcaa gtctacaacc
    15541 tctgtgtcca agcattgggt taaactcatc taaatcaact attctcttct taatatcact
    15601 tacttttatt cccatagatt ttgaaagttc ttctatagtc tcatcatcat gaggcaaaaa
    15661 ttcatgtagt ggtgggtcta gtaatcttat attaactggt tttccatcca taactttaaa
    15721 taactctaca aaatcctctc tttgcattgg taatattttt tcaagagctt tttctctttg
    15781 ttctactgta ttagataata tcatttctct aactgctggc aatctagctt catcaaagaa
    15841 catatgctca gttctacata gacctatacc ttctgcacca aactctatag ctgcacgagc
    15901 atctctagga ttatctgcat tagttctaac catcatacat ttgtgtttgt ctacccagtt
    15961 cattaatttt tcaaaatttc cagttaaaga tacttctgtt ttcttaacat ctcctaggta
    16021 cacatttcct gtagaaccat ctatagaaat gtattctcct tcttttataa ctacatcatc
    16081 aagtgctctt atttctttat taaactcatc aacttttatt tctccacatc cagcaacaca
    16141 acatttaccc atacctctag caacaactgc tgcatgtgac gtcattccac ctctagctgt
    16201 aaggattcct tctgctttaa ccattccttc tatatcttct ggagatgtct ctagtctaac
    16261 taaaactact ttttctcctt tttcatttgc ttttactaca tcatcagcat tgaaataaac
    16321 tttaccactt gctgcacctg gtgatgctgg taaacctttt gctataacct tggcttcttt
    16381 taatgcctta tcttcaaatt ttggatgtaa taattggtct aattgattag gctcaattct
    16441 catgatagcc tctttttcat caattattcc agcttcaact aaatcaaccg ctacatttat
    16501 tgctgctgct gctgttctct taccatttct agtttgtagt atatataatc tttcattttc
    16561 tatagtaaac tctatatctt gcatatcttt ataatgacct tcaagtatat gagtaatttt
    16621 tacaaattca tcgaatacag ctggcattac atctgcaaga gttgatatat tttgaggagt
    16681 tcttatacct gcaacaacgt cttcaccttg tgcattcatt aaaaattcac caaataattt
    16741 attttctcct gtagctggat ttctagtaaa tgcaacacct gtaccactag tttctcccat
    16801 attaccaaat accattgatt gaatatttac tgctgttcct aagttatgag ctatatcatt
    16861 caatttacgg tatacgattg cacgaggatt attccatgat ctaaatacag cctctattgc
    16921 aagcattaat tgctcttttg ggtcttgtgg gaaatcattt tttatttctt ttttataaat
    16981 tgctttaaat tcttttacta tttcttttaa atcatcagtt gtaagttctg tatcaactgt
    17041 gtatcccttt gcttctttta ctctgtctaa tacattttca aatttatatt ttggaacttc
    17101 catagcaaca tcagaaaaca tttgtatgaa tcttctgtaa ctatcatatg caaatctttc
    17161 attttgtgta gcctctgcta agccaacaac actattgtca ttaagaccta ggttaagaat
    17221 tgtatccatc attcctggca tagagaatac tgcaccagaa cgaactgata ctaataatgg
    17281 attcttattg catcctaatg ttttatttaa gtctttttct aaagtagcta aatgctcttc
    17341 tatttctttt attatctctg ctcttatact ttcattgtta acataataat cattacatgc
    17401 ttctgttgtt atagtgaatc caggagggac aggtaagcct atcttagtca tttctgctaa
    17461 attggcacct ttacctccta gtaaagattt catgtctttg cttccttcac caaaactata
    17521 aacatactta gtttccattg ttaaatcccc cattaatctt tttattttaa tttatatcat
    17581 ttttattaat agacattatt aaatttctat ttctttgtat atctttagac cattttcttt
    17641 cattatgtct aaaattatac ctgctgtttc ttctattgcc ttatttgaaa cgtttattac
    17701 tgggcatcca attcttttca ttatctcttc tgaataatct aactcctgaa gtattctttc
    17761 taaattagcg tagtttgctt tactggacaa tcctaaagct tttaatcttt gggttcttat
    17821 ctcattcagc ttttcaggtg aattagtaag acctattatt tttttagtat ctatctcaaa
    17881 cacttcttta ggaattggta tttctggaac taatggaaca ttagctactt ttatattttt
    17941 attagctaaa tacatactca aaggagtttt agatgttctt gatattccca ctaaaattat
    18001 gtctgcttga agaacacctc tagggtcttt tccatcatca tatttcactg caaattctat
    18061 agcttcaact ctcttaaagt aagattcatc taattttcta attataccag cttctctttt
    18121 aggttttctt cctgttctct tgcttatttc tcttagtata tctgtcatta aatctataca
    18181 actaagacct tctctttcgc aatatctttc aacaatactg cataattctt catcaactaa
    18241 tgtatataca attaaagcgt tttcagcttt tgcattctcc aaagtttcaa gtagtactcc
    18301 tttattaatc atgtatggaa atctttttat ttcataagtt tcattcacat aaaactgaga
    18361 catacatgcc tttgcaactt gttgtgcagt ctcccctact gaatctgata ctgcatatat
    18421 aattaggttt ttcaccagca tacctcctta attgtcaact atttctaaga atagcttagt
    18481 tatgttggtt tttgatattc tcccaacaac tctcatatga tttttgtctt ctcccttata
    18541 ttcaacaatc ggaatcgaat ctacttcatg ttctattatt tttcttgaag ctaataaaac
    18601 acttgctcct ttagttaaag tgactacatt tggagttctt gtcattatca tacctattgg
    18661 cattttattt atatcagaac ctcctatagt tgcttttagc aagtcttttc tggaaacaac
    18721 tccacataac tcttcattct catctataat aactatactc cctacatcag ataaaaacat
    18781 agtgactatt acatcatata tactttcatc cttcttagct agtacaggca tgctcattat
    18841 atcctctact gttttttctt ttacactttt accaattaaa tttatttcac taactcctga
    18901 ataaaaatat ccaacttttg gtcttgcgtc taatattcct gtcattgtta atatagctaa
    18961 atcagatcta agtgtagcac gagtcacatt caagctggag gcaatacttt cactcgttat
    19021 tggttcattt tccttaacta tatctataat ttttagttgt ctttcattaa gctgaataat
    19081 aatcaccttc tttcattgtg ctatactttt tatcttttcg catcttatat agtatattat
    19141 ataactatat ataccattct gtaaacagat tttttattga atacgatata ttttttacta
    19201 agttctctcg cttaaagata tttattatat attaatgggg gatatttctt taattaatag
    19261 aactatatta gtattacagt taatattata atacataatt ggtcatttta attcatttta
    19321 tattaaaatt tttaataata ttatttcaat gtgaatataa aattgcagaa ctaattcaaa
    19381 ataattttta cgactacaaa taacctataa tatactttta aagaaagtat cctaacaaga
    19441 atatataaaa atttaaaagg gttgatttaa aaataaccat caaccctttt tactaatatc
    19501 tatttatatt accatcaaat cttacccaaa tattttttct tgcaattgtc ttaaatgata
    19561 taaagtagta tctttttcta tctctaccat atcgtaagtt ataacttcac cttttttaat
    19621 atcttttaca actttagtct ttttacttat caaaccaata ggtacagcat tcatagcctt
    19681 tgctacatcg tatttttcta tagtaccata gcatgtatat gctccatagc catccataaa
    19741 ctcacctttt ttcaaatctt tcttagctat agtcataact tctgctacta gtccagcttt
    19801 aggtactatt gtagccttat ggtctaagac tgccatagct gctgataaag gagtctctaa
    19861 actacataaa tgatatggtc tatataatat gtaattaggt ccatcaccca tacttaaata
    19921 ttttagttca tcattaactg cttttaattt atgggctact actacgaaaa ctccaggtgc
    19981 tataccattt acaaaatcaa ctacaccata attatctaat actccacctt cgctttttaa
    20041 tgcatatttc ttaggtactt cattaactgt agcttcaata ccatgaccac ctcttacatc
    20101 aggcacaaat ccagttgcat tacacattaa agccatttct accattgttt tagttccttc
    20161 tttaaaagaa gctatcatat gaggtgaagc tccttttctt tctgcttctt ctctaactgt
    20221 atcaggatta caatctaaat ctaatttatt atttttacct ttacctatca ctctaacttc
    20281 aaaccccatt gcatctgcaa aatcaaataa ttccattact gcacctggct catctcctgc
    20341 agaacctgta aatattactc cagcatcatc tgctaatttt ttaagtattg gtccaacaac
    20401 acaatcagtt tcagcattta acataactat atgtttttta tttaaaatag agtttaatgc
    20461 tatctctgca ccaattgcaa tacctccagt tgcatctata actacatcta ttgacttagt
    20521 tttacaagcc acaagaaaat cattacatgt caatactttt ccttcttgta attttatttc
    20581 tgcatccttt tcatttgtta cattatctat aatttcttca tctattcctg catcagtaaa
    20641 agctttatga gccaactcca aatttatatc tacaacaata gaagcttcaa tacctttcat
    20701 atttgccatt tggcttacca ttccatttcc catatgccca gctcctataa gagctacttt
    20761 tattttttta ccttcctctt ccaattttgc aagttttctg tttaaatcta acataccaat
    20821 tcctcctgtt ataataattt tattttcaaa ttaagaaata gttattaaat ctccaatagt
    20881 tatatctgga tttcctattt ccacatgtat ttctcctggt aaatttactt cacattttcc
    20941 atcaaatttg attgtacaat gcccaatttc tctaagagtc ttctgagcaa tatcaccaac
    21001 tgaaactata caataatctc tattccctat agtaagtgta tctcctattt caacatcact
    21061 ttttaacgtt gctattgaat gaattacaga tatatccttt aagtcgtcat cattaatggt
    21121 ttcatcatat ataataagac aattgctttc atccattaac tctttaacta aactgcctat
    21181 cccacttatc ttaacttcat atttcatgac attcctcctg ataatttata tttatattga
    21241 gttaattaaa agaaacattt attttttctt ttataaattt tatagcttgt acaatactct
    21301 cttcatcttt aaatttttgc tctgcactat atatatctaa tccttctatt tcttcaatct
    21361 ctttaaattt agccattact gtacgtcctt ttaaaatttc tccaaacttt ataaacccat
    21421 ctgaatctga agatataatg gctatacttc ctttagaaaa atagcttttc tttttgcctg
    21481 tagacactat atcacccttt tttttagctc tatttaaagt tttaaaatac aatttattct
    21541 gcttcattat aaatatagta tttaaaatat aagcaacaaa taaaatcact aataatttca
    21601 tatttataca ccttccaaaa atcacattat ttttaaatct gtataacaac tataaatgct
    21661 gtacaatagt tatataaggt ttttaagtaa caccttttta aattctaaaa aagttctaca
    21721 tttacttatc ttattcgtta attttacatc ttggcctatc tttaaaactt cttcataaat
    21781 ttttactaat aagtctgagt ctatcttatt ctcacatgga aacattgtca taagaattat
    21841 ttttatactt ctatttgcat attctattgg ttcttctaaa attccaactg ccattaaaaa
    21901 cttatctgat ttttcattta cagaatgagg aaataataaa cctttatcaa atactgtggg
    21961 agatttttct tctctattga ctatattttt tctaaactta tcatcaatgc atcctaaatc
    22021 cataagatgg tccatcattt tttctaatga agcaagtata gtcttttcat ttaatatcat
    22081 aaatttatct tcatctaaca aattatttat tagtaaattt gtagaattag tagtgtcaat
    22141 attcccttct cttaggcaca atactgtttt taattgttct cttagtttgt tttcatcaaa
    22201 tattgtattt atttttaata ctattgtatt tatatttgat gtgtctaaat caatagttgt
    22261 aaaaactata tcatattcat ctaagttaat atttctcaaa ttaaaacttg aaagagtatc
    22321 aattttagga ttatttccta tcagtttttc tactcttatt ttcaatagtt ttgctgttcc
    22381 tagacctgta ctacatataa ttgctatttt ttttattgaa tagaatctac tgctatttct
    22441 ttctaaatat ccactgaaat ggattgctat atatccaatc tcatcttctg aaacttctaa
    22501 gttatacttt ttctctatta cttttcctgc tatttgtgct aatttaaatg gaagtatata
    22561 attttgctta atctcttcta acaaaacatt ttttaacttt atattaaata atagcctgtt
    22621 taaagtaaaa ctaagatgat atcctagacc tactcttaat tcatcctcat ttataaaaat
    22681 acccatatcg acatatattt gattaaatat attttccatc aactcatcaa tgtttttact
    22741 aattctacta ctatttaaag cacattctga tgctggtgca tttccactaa ctaacggtat
    22801 agttaaataa ataatttctt catcatttaa agtacattca aacattcctg atattatatg
    22861 ttttatttcc ctagcaataa agtattcatc atatgattta agtaaatcaa actttacatc
    22921 ataatctttt actttctttt cttcttttac tctatagact aaaactacta tgtagttaat
    22981 aacttctctt aacatttcat ctgtaacata aaaattattt tttttaaata aagtcaatag
    23041 tttttcttct aaatttatga tttcttcttt tttgattcct ttaaaatact ttgaattact
    23101 gaaatctttc cttgagtttt tatacaactg atttaatata aacagtctaa tatcaagttc
    23161 atttccattt aatttcatac ctgtattctg ttttttaatc aagtttaaat tatatgaagc
    23221 caaaactttt tctacatact ggaaatcatt tactaaagta gttcttccta cacacatctc
    23281 atcagctaaa ctatcaagtg taataaatcc atctagttct atcaagtaat ttagtataaa
    23341 ctctactcta tcttcttttg aatttaatga aaatacattt tttctattca tatcaataat
    23401 cttattgagt atctgctcat cttttatttc tagtttatag ccttgaccct ttatatattt
    23461 gattactgct atatcattac ctaaatcttt attcaattgt tttatatacg tccttacact
    23521 tctagttgtg acattcaatt catttgctat tgagttaata ctcacaaact cttttttact
    23581 acacataatc aatatcttaa atatcttgcg gtcaatagaa ggaattttct cagttacact
    23641 cattttgtat ctcctccttg atttcattct agtacaaatt tgaaaccaaa ttaatacata
    23701 aaatttcact ttaataaagg aaaatttagt attaatctaa ctcgataatt acagctaatt
    23761 aatagtataa aagctagtct ttcattaaca aaaaatcttg actagcttaa atttatattt
    23821 acaattttat taattaattc caagccttat attgacatta aatattatct caatgcaaat
    23881 actgcaactc catatgcaat aataacagct attggaccag ttattaaacg agagtaaaat
    23941 aaagctggaa caccatactc tacagtttct ggttctgctt ctcccaaact taatcctact
    24001 ggtacaaaat cacatccagc ttgcccattt attgcaaata aagctggaag tgctaaatat
    24061 gctggtattg caccaagacc aatttgtgta cctacaagag tccctactac ttgagctata
    24121 actgcaccag gtcctagtat tggtgataag aatggaagtg tgcaaattac tgatataatc
    24181 aataatccac caatattacc tgcaagtgga gatataactc ttgcaatcca gtctcccagt
    24241 ccagatgcta aaataattcc cataagcata cttacaaatg ccataaatgg tattacgtta
    24301 ttcattacca tttggatagt atctcgacct gcatcataaa attttgatac tacttgccct
    24361 gccccttgac caatagaaag tattatgttc tttttagcat attcaccttg tgcttttgac
    24421 ttaacctcat cataattatc aggctttcta atagaactct tattttcgct tttattttct
    24481 tgagattttt gtggcatatc ttccccatct acaacactta tacagttagg attaacatct
    24541 gatacataat attcttctgt tataaatttt gctaaaggac ctgtttttcc aactggattt
    24601 acatttattg taggtatttt tttctttgga taaactccac atctagcagt tccaccacaa
    24661 tcaataataa ctactgctac ttcttcatca gaaactccag ttttaaatcc atctacaatt
    24721 tcacaaccca gtagttcttt tatttttaat gttacttcat ggataccacc agcagtcatt
    24781 gacagtatct tatttctatt cccttctttt tttatataca aaggacctcc ccagcctgaa
    24841 gttccctttt ctatttttaa tattttattc tcctccattt tatctacctc ctaagcctta
    24901 tttgttgctc tattttttct tgttagaaaa gcatacattt tttctgttac tatacctctt
    24961 ataaaaatta caattagacc aactataaaa taccacaatg ccaatgtagt agtttcttta
    25021 cctaaagtag tcaaacctgc agatattccc aaccatacaa aaagttctcc tgcatttgca
    25081 tgtggaaaaa gacctgtaat tggatgtaca aatgaaactg ctgcatcata aaatcctgct
    25141 ttgtgctctt cttttaaaaa tctaccaaat gtatagcaca taggatttcc caagaaaaat
    25201 actgatacta atggaagtag aatatatctt gtaaaagagt tctttcctag cttagaagcc
    25261 caattattaa ctctttcctc accaattatc ttaatcaaag agttaatagc taccattaat
    25321 acaattagcg ttggaagagt acctgaaaca agacctataa attgttctcc ccctttctga
    25381 aacaaaccga taaaccactc tgcaccttta cttagacctg taataacgtt ttccataaaa
    25441 ttataacctc cctataatat ctttaaattt ttaattttac tgcttaccat aaattttaca
    25501 aattacatct tttttctgta ctatatgcta atattgtaaa tgttttttta ttaatatcat
    25561 tttaatataa tatttttgat aaataaatac atcttttttc aattttataa aggaaaaaa
//
LOCUS       DAJMZY010000053        25481 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.053, whole genome shotgun sequence.
ACCESSION   DAJMZY010000053 DAJMZY010000000
VERSION     DAJMZY010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 25481)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25481)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25481
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.053"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            <1..6881
                     /gene="tcdB"
                     /locus_tag="OE968_002120"
                     /gene_synonym="toxB"
     CDS             <1..6881
                     /gene="tcdB"
                     /locus_tag="OE968_002120"
                     /gene_synonym="toxB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_074049122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="glycosylating toxin TcdB"
                     /protein_id="HCP7219399.1"
                     /translation="FKEYLVTEVLELKNNNLTPVEKNLHFVWIGGQINDTAINYINQW
                     KDVNSDYNVNVFYDSNAFLINTLKKTVVESAINDTLESFRENLNDPRFDYNKFFRKRM
                     EIIYDKQKNFINYYKAQREENPELIIDDIVKTYLSNEYSKEIDELNTYIEESLNKITQ
                     NSGNDVRNFEEFKNGESFNLYEQELVERWNLAAASDILRISALKEIGGMYLDVDMLPG
                     IQPDLFESIEKPSSVTVDFWEMTKLEAIMKYKEYIPEYTSEHFDMLDEEVQSSFESVL
                     ASKSDKSEIFSSLGDMEASPLEVKIAFNSKGIINQGLISVKDSYCSNLIVKQIENRYK
                     ILNNSLNPAISEDNDFNTTTNTFIDSIMAEANADNGRFMMELGKYLRVGFFPDVKTTI
                     NLSGPEAYAAAYQDLLMFKEGSMNIHLIEADLRNFEISKTNISQSTEQEMASLWSFDD
                     ARAKAQFEEYKRNYFEGSLGEDDNLDFSQNIVVDKEYLLEKISSLARSSERGYIHYIV
                     QLQGDKISYEAACNLFAKTPYDSVLFQKNIEDSEIAYYYNPGDGEIQEIDKYKIPSII
                     SDRPKIKLTFIGHGKDEFNTDIFAGFDVDSLSTEIEAAIDLAKEDISPKSIEINLLGC
                     NMFSYSINVEETYPGKLLLKVKDKISELMPSISQDSIIVSANQYEVRINSEGRRELLD
                     HSGEWINKEESIIKDISSKEYISFNPKENKITVKSKNLPELSTLLQEIRNNSNSSDIE
                     LEEKVMLTECEINVISNIDTQIVEERIEEAKNLTSDSINYIKDEFKLIESISDALCDL
                     KQQNELEDSHFISFEDISETDEGFSIRFINKETGESIFVETEKTIFSEYANHITEEIS
                     KIKGTIFDTVNGKLVKKVNLDTTHEVNTLNAAFFIQSLIEYNSSKESLSNLSVAMKVQ
                     VYAQLFSTGLNTITDAAKVVELVSTALDETIDLLPTLSEGLPIIATIIDGVSLGAAIK
                     ELSETSDPLLRQEIEAKIGIMAVNLTTATTAIITSSLGVASGFSILLVPLAGISAGIP
                     SLVNNELVLRDKATKVVDYFKHVSLVETEGVFTLLDDKIMMPQDDLVISEIDFNNNSI
                     VLGKCEIWRMEGGSGHTVTDDIDHFFSAPSITYREPHLSIYDVLEVQKEELDLSKDLM
                     VLPNAPNRVFAWETGWTPGLRSLENDGTKLLDRIRDNYEGEFYWRYFAFIADALITTL
                     KPRYEDTNIRINLDSNTRSFIVPIITTEYIREKLSYSFYGSGGTYALSLSQYNMGINI
                     ELSESDVWIIDVDNVVRDVTIESDKIKKGDLIEGILSTLSIEENKIILNSHEINFSGE
                     VNGSNGFVSLTFSILEGINAIIEVDLLSKSYKLLISGELKILMLNSNHIQQKIDYIGF
                     NSELQKNIPYSFVDSEGKENGFINGSTKEGLFVSELPDVVLISKVYMDDSKPSFGYYS
                     NNLKDVKVITKDNVNILTGYYLKDDIKISLSLTLQDEKTIKLNSVHLDESGVAEILKF
                     MNRKGNTNTSDSLMSFLESMNIKSIFVNFLQSNIKFILDANFIISGTTSIGQFEFICD
                     ENDNIQPYFIKFNTLETNYTLYVGNRQNMIVEPNYDLDDSGDISSTVINFSQKYLYGI
                     DSCVNKVVISPNIYTDEINITPVYETNNTYPEVIVLDANYINEKINVNINDLSIRYVW
                     SNDGNDFILMSTSEENKVSQVKIRFVNVFKDKTLANKLSFNFSDKQDVPVSEIILSFT
                     PSYYEDGLIGYDLGLVSLYNEKFYINNFGMMVSGLIYINDSLYYFKPPVNNLITGFVT
                     VGDDKYYFNPINGGAASIGETIIDDKNYYFNQSGVLQTGVFSTEDGFKYFAPANTLDE
                     NLEGEAIDFTGKLIIDENIYYFDDNYRGAVEWKELDGEMHYFSPETGKAFKGLNQIGD
                     YKYYFNSDGVMQKGFVSINDNKHYFDDSGVMKVGYTEIDGKHFYFAENGEMQIGVFNT
                     EDGFKYFAHHNEDLGNEEGEEISYSGILNFNNKIYYFDDSFTAVVGWKDLEDGSKYYF
                     DEDTAEAYIGLSLINDGQYYFNDDGIMQVGFVTINDKVFYFSDSGIIESGVQNIDDNY
                     FYIDDNGIVQIGVFDTSDGYKYFAPANTVNDNIYGQAVEYSGLVRVGEDVYYFGETYT
                     IETGWIYDMENESDKYYFNPETKKACKGINLIDDIKYYFDEKGIMRTGLISFENNNYY
                     FNENGEMQFGYINIEDKMFYFGEDGVMQIGVFNTPDGFKYFAHQNTLDENFEGESINY
                     TGWLDLDEKRYYFTDEYIAATGSVIIDGEEYYFDPDTAQLVISE"
     gene            7003..7503
                     /gene="tcdE"
                     /locus_tag="OE968_002121"
     CDS             7003..7503
                     /gene="tcdE"
                     /locus_tag="OE968_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holin-like glycosylating toxin export protein
                     TcdE"
                     /protein_id="HCP7219400.1"
                     /translation="MHSSSPFYISNGNKIFFYINLGGVMNMTISFLSEHIFIKLVILT
                     ISFDTLLGCLSAIKSRKFNSSFGIDGGIRKVAMIACIFFLSVVDILTKFNFLFMLPQD
                     CINFLRLKHLGISEFFSILFILYESVSILKNMCLCGLPVPKRLKEKIAILLDAMTDEM
                     NAKDEK"
     gene            7832..8014
                     /locus_tag="OE968_002122"
     CDS             7832..8014
                     /locus_tag="OE968_002122"
                     /inference="COORDINATES: protein motif:HMM:NF022413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219401.1"
                     /translation="MRDEGQNDIENKYQTLINDLIDSLKVIGKIYKEIKTLKKYKICL
                     QITIRQSPYLIEESIN"
     gene            8231..16363
                     /gene="tcdA"
                     /locus_tag="OE968_002123"
                     /gene_synonym="toxA"
     CDS             8231..16363
                     /gene="tcdA"
                     /locus_tag="OE968_002123"
                     /gene_synonym="toxA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_105161403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosylating toxin TcdA"
                     /protein_id="HCP7219402.1"
                     /translation="MSLISKEELIKLAYSIRPRENEYKTILTNLDEYNKLTTNNNENK
                     YLQLKKLNESIDVFMNKYKTSSRNRALSNLKKDILKEVILIKNSNTSPVEKNLHFVWI
                     GGEVSDIALEYIKQWADINAEYNIKLWYDSEAFLVNTLKKAIVESSTTEALQLLEEEI
                     QNPQFDNMKFYKKRMEFIYDRQKRFINYYKSQINKPTVPTIDDIIKSHLVSEYNRDET
                     VLESYRTNSLRKINSNHGIDIRANSLFTEQELLNIYSQELLNRGNLAAASDIVRLLAL
                     KNFGGVYLDVDMLPGIHSDLFKTISRPSSIGLDRWEMIKLEAIMKYKKYINNYTSENF
                     DKLDQQLKDNFKLIIESKSEKSEIFSKLENLNVSDLEIKIAFALGSVINQALISKQGS
                     YLTNLVIEQVKNRYQFLNQHLNPAIESDNNFTDTTKIFHDSLFNSATAENSMFLTKIA
                     PYLQVGFMPEARSTISLSGPGAYASAYYDFINLQENTIEKTLKASDLIEFKFPENNLS
                     QLTEQEINSLWSFDQASAKYQFEKYVRDYTGGSLSEDNGVDFNKNTALDKNYLLNNKI
                     PSNNVEEAGSKNYVHYIIQLQGDDISYEATCNLFSKNPKNSIIIQRNMNESAKSYFLS
                     DDGESILELNKYRIPERLKNKEKVKVTFIGHGKDEFNTSEFARLSVDSLSNEISSFLD
                     TIKLDISPKNVEVNLLGCNMFSYDFNVEETYPGKLLLSIMDKITSTLPDVNKNSITIG
                     ANQYEVRINSEGRKELLAHSGKWINKEEAIMSDLSSKEYIFFDSIDNKLKAKSKNIPG
                     LASISEDIKTLLLDASVSPDTKFILNNLKLNIESSIGDYIYYEKLEPVKNIIHNSIDD
                     LIDEFNLLENVSDELYELKKLNNLDEKYLISFEDISKNNSTYSVRFINKSNGESVYVE
                     TEKEIFSKYSEHITKEISTIKNSIITDVNGNLLDNIQLDHTSQVNTLNAAFFIQSLID
                     YSSNKDVLNDLSTSVKVQLYAQLFSTGLNTIYDSIQLVNLISNAVNDTINVLPTITEG
                     IPIVSTILDGINLGAAIKELLDEHDPLLKKELEAKVGVLAINMSLSIAATVASIVGIG
                     AEVTIFLLPIAGISAGIPSLVNNELILHDKATSVVNYFNHLSESKKYGPLKTEDDKIL
                     VPIDDLVISEIDFNNNSIKLGTCNILAMEGGSGHTVTGNIDHFFSSPSISSHIPSLSI
                     YSAIGIETENLDFSKKIMMLPNAPSRVFWWETGAVPGLRSLENDGTRLLDSIRDLYPG
                     KFYWRFYAFFDYAITTLKPVYEDTNIKIKLDKDTRNFIMPTITTNEIRNKLSYSFDGA
                     GGTYSLLLSSYPISTNINLSKDDLWIFNIDNEVREISIENGTIKKGKLIKDVLSKIDI
                     NKNKLIIGNQTIDFSGDIDNKDRYIFLTCELDDKISLIIEINLVAKSYSLLLSGDKNY
                     LISNLSNTIEKINTLGLDSKNIAYNYTDESNNKYFGAISKTSQKSIIHYKKDSKNILE
                     FYNDSTLEFNSKDFIAEDINVFMKDDINTITGKYYVDNNTDKSIDFSISLVSKNQVKV
                     NGLYLNESVYSSYLDFVKNSDGHHNTSNFMNLFLDNISFWKLFGFENINFVIDKYFTL
                     VGKTNLGYVEFICDNNKNIDIYFGEWKTSSSKSTIFSGNGRNVVVEPIYNPDTGEDIS
                     TSLDFSYEPLYGIDRYINKVLIAPDLYTSLININTNYYSNEYYPEIIVLNPNTFHKKV
                     NINLDSSSFEYKWSTEGSDFILVRYLEESNKKILQKIRIKGILSNTQSFNKMSIDFKD
                     IKKLSLGYIMSNFKSFNSENELDRDHLGFKIIDNKTYYYDEDSKLVKGLININNSLFY
                     FDPIEFNLVTGWQTINGKKYYFDINTGAALTSYKIINGKHFYFNNDGVMQLGVFKGPD
                     GFEYFAPANTQNNNIEGQAIVYQSKFLTLNGKKYYFDNDSKAVTGWRIINNEKYYFNP
                     NNAIAAVGLQVIDNNKYYFNPDTAIISKGWQTVNGSRYYFDTDTAIAFNGYKTIDGKH
                     FYFDSDCVVKIGVFSTSNGFEYFAPANTYNNNIEGQAIVYQSKFLTLNGKKYYFDNNS
                     KAVTGWQTIDSKKYYFNTNTAEAATGWQTIDGKKYYFNTNTAEAATGWQTIDGKKYYF
                     NTNTAIASTGYTIINGKHFYFNTDGIMQIGVFKGPNGFEYFAPANTDANNIEGQAILY
                     QNEFLTLNGKKYYFGSDSKAVTGWRIINNKKYYFNPNNAIAAIHLCTINNDKYYFSYD
                     GILQNGYITIERNNFYFDANNESKMVTGVFKGPNGFEYFAPANTHNNNIEGQAIVYQN
                     KFLTLNGKKYYFDNDSKAVTGWQTIDGKKYYFNLNTAEAATGWQTIDGKKYYFNLNTA
                     EAATGWQTIDGKKYYFNTNTFIASTGYTSINGKHFYFNTDGIMQIGVFKGPNGFEYFA
                     PANTHNNNIEGQAILYQNKFLTLNGKKYYFGSDSKAVTGLRTIDGKKYYFNTNTAVAV
                     TGWQTINGKKYYFNTNTSIASTGYTIISGKHFYFNTDGIMQIGVFKGPDGFEYFAPAN
                     TDANNIEGQAIRYQNRFLYLHDNIYYFGNNSKAATGWVTIDGNRYYFEPNTAMGANGY
                     KTIDNKNFYFRNGLPQIGVFKGSNGFEYFAPANTDANNIEGQAIRYQNRFLHLLGKIY
                     YFGNNSKAVTGWQTINGKVYYFMPDTAMAAAGGLFEIDGVIYFFGVDGVKAPGIYG"
     gene            complement(16698..17396)
                     /gene="tcdC"
                     /locus_tag="OE968_002124"
     CDS             complement(16698..17396)
                     /gene="tcdC"
                     /locus_tag="OE968_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosylating toxin anti-sigma factor TcdC"
                     /protein_id="HCP7219403.1"
                     /translation="MFSKKNDGNEFSNEGKGSSKKIIKFFKSTKGIALLAFILGVFFG
                     NISSPACSEDHEEVISNQTSVIDSQKTEIETLNSKLSDAEPWFKMKDDEKKAIEAENQ
                     RKAEEAKKAEEAKKAEEQRKKEEEEKKGYDTGITYDQLARTPDDYKYKKVKFEGKVIQ
                     VIEDGDEVQIRLAVSGNYDKVVLCSYKKSITPSRVLEDDYITIRGISAGTITYESTMG
                     GNITIPGIAVEKIN"
     gene            17822..18067
                     /locus_tag="OE968_002125"
     CDS             17822..18067
                     /locus_tag="OE968_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Pathogenicity locus"
                     /protein_id="HCP7219404.1"
                     /translation="MGELQKIPGVGKATEKSLIMLGYTTIKSLKDANPAQMYEKECLI
                     RGQHIDRCQLYVYRCAVYFASTENPEPEKLKWWYWKD"
     gene            complement(18285..18554)
                     /locus_tag="OE968_002126"
     CDS             complement(18285..18554)
                     /locus_tag="OE968_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3795 domain-containing protein"
                     /protein_id="HCP7219405.1"
                     /translation="MFESRCGVCCDSCTKKEQVNCTGCPTMEKPFWGGECKVKTCCES
                     KELNHCGECDTFPCDMLLNKGKDQGFDPMVNIEQCRKWLEETVSN"
     gene            complement(19432..20169)
                     /locus_tag="OE968_002127"
     CDS             complement(19432..20169)
                     /locus_tag="OE968_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCP7219406.1"
                     /translation="MLRKSVLGEILKLKNSFIWYVLLALPLISVLIGSGNFYLNQGIL
                     KKEWYSLWTQVSLFYGEFFFPILIAIFCAYICRLEHMNHNWNNVMTLPVNLKNIFLSK
                     LTVVSILTAITQVFFVIFYIVAGNMFGFSGSVPKELTGWIAKGWIISISIASIQLYMS
                     IKIRSFATPIGISLCLSLFGMGLIVAKPAVGIFFPYSMLGSAMGVIKQSALNVNDTIV
                     TICVAFITTIVFSEIANRNFRKNDVIS"
     gene            complement(20181..20942)
                     /locus_tag="OE968_002128"
     CDS             complement(20181..20942)
                     /locus_tag="OE968_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCP7219407.1"
                     /translation="MKYLGLEFYKLKRKKIILMTFLFVAVEIMWCIINSNRAITRNPD
                     MLGGFEYSYMFMSFASLNGLFFPILISIITSRISDIEHKGDTWKLLKSSVTSLNSIYL
                     SKFLCSAILVSIPVLMQVLSIVLFGHFRGVIESISVSLLLKYTLGTILVSIAIIALHL
                     WIATVIPNQMIAITFGMIGSFIGLTSGLFYQGIRRLFIWSYYLELSPLSYAYDNVLGS
                     SVYRIDMNFSITILVFLIGMLIYYIGRNHLLKKEV"
     gene            complement(20942..21856)
                     /locus_tag="OE968_002129"
     CDS             complement(20942..21856)
                     /locus_tag="OE968_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCP7219408.1"
                     /translation="MEMIIRTQRLSKEYNKIFRVKDIDLRVPQGAVYGFLGPNGAGKS
                     TTLKMLLGLAKPTQGNINILGKELNEKNRISILKDIGSLIESPSYYGHLTGLENMTIM
                     QKLLDLPKKNVNEALKIVRLENQKNKKVSQYSLGMKQRLGIAMAIMKFPKLLILDEPT
                     NGLDPAGIEEIRELIKSLPEKYGMTVLISSHLLSEIDQIATSIGIINHGELVFQDSIK
                     ELHNRGQSQIAIKTKNVVSAQKLLNTKGYMSLIQDGYLTIENLKDSDVAKINGMLVHS
                     NIDVFRIEEHKKSLEDIFLELTGKAVTL"
     gene            22027..22734
                     /locus_tag="OE968_002130"
     CDS             22027..22734
                     /locus_tag="OE968_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCP7219409.1"
                     /translation="MESIKDKKILVVDDHKELLKMIDEILRKEGFSRVFLASSYEEAV
                     RVFRNVKPDCAILDVVLPDGDGFSIMRKIRETSKIPVIFLSARGEDEDRLIGLGLGAD
                     DYIVKPFLPKELTLRLVGILNRVYVPIEEEELPVFKLGDSVVVNLNSACVEKDGQEIS
                     LTAKEHSLLLKLYENKGRIVTNDSLCQAIWGDDMYGYENTLMVHVRRVREKIEKTPST
                     PKHLITVRGLGYKLMIN"
     gene            22779..24185
                     /locus_tag="OE968_002131"
     CDS             22779..24185
                     /locus_tag="OE968_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HCP7219410.1"
                     /translation="MDSVKYILRRFIGSSILISLLFIVLNIAGFLLFSYMLFVSKYSD
                     NLDTSDSREIKSNLIMIEDNLILRNGKFILDDSSKEVLHKNKVWAMLIDNNGDRIWGF
                     DLPKEIPSHYTLTDVAKFSRFFLKDYPVYVWEHPNGILVTGYPKDKYTKFNLTYTVKE
                     IEQFPMLIIGMFLVNAIVTFLIALFIGLKMVKSIKPIITGIKLMSKGEPVLLQEKGIL
                     SDISKSINTVSKELQMKDEKLRKKEEARSNWIAGISHDIRTPLSMIIGYAGELEESSS
                     LSNREQEQVSIICNQGIKIRELVNDLNLVSKLEYNMQALNCDKIRVSAFLRELISEFI
                     NNNLDNDFYVEFDILNEDIIIDADKKLLKRAISNLIQNSITHNQQGCNIRVTSKSDLD
                     FCYIIVEDDGKGMSQERINSLLKSQNGLSEAYAKGQNHGLGILIVSGIINAHRGKLDI
                     TSIDSQGLKTILKLPLIK"
BASE COUNT         9949 a         2932 c         3921 g         8679 t
ORIGIN      
        1 aatttaagga atatctagtt acagaagtat tagagctaaa gaataataat ttaactccag
       61 ttgagaaaaa tttacatttt gtttggattg gaggtcaaat aaatgacact gctattaatt
      121 atataaatca atggaaagat gtaaatagtg attataatgt taatgttttt tatgatagta
      181 atgcattttt gataaacaca ttgaaaaaaa ctgtagtaga atcagcaata aatgatacac
      241 ttgaatcatt tagagaaaac ttaaatgacc ctagatttga ctataataaa ttcttcagaa
      301 aacgtatgga aataatttat gataaacaga aaaatttcat aaactactat aaagctcaaa
      361 gagaagaaaa tcctgaactt ataattgatg atattgtaaa gacatatctt tcaaatgagt
      421 attcaaagga gatagatgaa cttaatacct atattgaaga atccttaaat aaaattacac
      481 agaatagtgg aaatgatgtt agaaactttg aagaatttaa aaatggagag tcattcaact
      541 tatatgaaca agagttggta gaaaggtgga atttagctgc tgcttctgac atattaagaa
      601 tatctgcatt aaaagaaatt ggtggtatgt atttagatgt tgatatgtta ccaggaatac
      661 aaccagactt atttgagtct atagagaaac ctagttcagt aacagtggat ttttgggaaa
      721 tgacaaagtt agaagctata atgaaataca aagaatatat accagaatat acctcagaac
      781 attttgacat gttagacgaa gaagttcaaa gtagttttga atctgttcta gcttctaagt
      841 cagataaatc agaaatattc tcatcacttg gtgatatgga ggcatcacca ctagaagtta
      901 aaattgcatt taatagtaag ggtattataa atcaagggct aatttctgtg aaagactcat
      961 attgtagcaa tttaatagta aaacaaatcg agaatagata taaaatattg aataatagtt
     1021 taaatccagc tattagcgag gataatgatt ttaatactac aacgaatacc tttattgata
     1081 gtataatggc tgaagctaat gcagataatg gtagatttat gatggaacta ggaaagtatt
     1141 taagagttgg tttcttccca gatgttaaaa ctactattaa cttaagtggc cctgaagcat
     1201 atgcggcagc ttatcaagat ttattaatgt ttaaagaagg cagtatgaat atccatttga
     1261 tagaagctga tttaagaaac tttgaaatct ctaaaactaa tatttctcaa tcaactgaac
     1321 aagaaatggc tagcttatgg tcatttgacg atgcaagagc taaagctcaa tttgaagaat
     1381 ataaaaggaa ttattttgaa ggttctcttg gtgaagatga taatcttgat ttttctcaaa
     1441 atatagtagt tgacaaggag tatcttttag aaaaaatatc ttcattagca agaagttcag
     1501 agagaggata tatacactat attgttcagt tacaaggaga taaaattagt tatgaagcag
     1561 catgtaactt atttgcaaag actccttatg atagtgtact atttcagaaa aatatagaag
     1621 attcagaaat tgcatattat tataatcctg gagatggtga aatacaagaa atagacaagt
     1681 ataaaattcc aagtataatt tctgatagac ctaagattaa attaacattt attggtcatg
     1741 gtaaagatga atttaatact gatatatttg caggttttga tgtagattca ttatccacag
     1801 aaatagaagc agcaatagat ttagctaaag aggatatttc tcctaagtca atagaaataa
     1861 atttattagg atgtaatatg tttagctact ctatcaacgt agaggagact tatcctggaa
     1921 aattattact taaagttaaa gataaaatat cagaattaat gccatctata agtcaagact
     1981 ctattatagt aagtgcaaat caatatgaag ttagaataaa tagtgaagga agaagagaat
     2041 tattggatca ttctggtgaa tggataaata aagaagaaag tattataaag gatatttcat
     2101 caaaagaata tatatcattt aatcctaaag aaaataaaat tacagtaaaa tctaaaaatt
     2161 tacctgagct atctacatta ttacaagaaa ttagaaataa ttctaattca agtgatattg
     2221 aactagaaga aaaagtaatg ttaacagaat gtgagataaa tgttatttca aatatagata
     2281 cgcaaattgt tgaggaaagg attgaagaag ctaagaattt aacttctgac tctattaatt
     2341 atataaaaga tgaatttaaa ctaatagaat ctatttctga tgcactatgt gacttaaaac
     2401 aacagaatga attagaagat tctcatttta tatcttttga ggacatatca gagactgatg
     2461 agggatttag tataagattt attaataaag aaactggaga atctatattt gtagaaactg
     2521 aaaaaacaat attctctgaa tatgctaatc atataactga agagatttct aagataaaag
     2581 gtactatatt tgatactgta aatggtaagt tagtaaaaaa agtaaattta gatactacac
     2641 acgaagtaaa tactttaaat gctgcatttt ttatacaatc attaatagaa tataatagtt
     2701 ctaaagaatc tcttagtaat ttaagtgtag caatgaaagt ccaagtttac gctcaattat
     2761 ttagtactgg tttaaatact attacagatg cagccaaagt tgttgaatta gtatcaactg
     2821 cattagatga aactatagac ttacttccta cattatctga aggattacct ataattgcaa
     2881 ctattataga tggtgtaagt ttaggtgcag caatcaaaga gctaagtgaa acgagtgacc
     2941 cattattaag acaagaaata gaagctaaga taggtataat ggcagtaaat ttaacaacag
     3001 ctacaactgc aatcattact tcatctttgg gggtagctag tggatttagt atacttttag
     3061 ttcctttagc aggaatttca gcaggtatac caagcttagt aaacaatgaa cttgtacttc
     3121 gagataaggc aacaaaggtt gtagattatt ttaaacatgt ttcattagtt gaaactgaag
     3181 gagtatttac tttattagat gataaaataa tgatgccaca agatgattta gtgatatcag
     3241 aaatagattt taataataat tcaatagttt taggtaaatg tgaaatctgg agaatggaag
     3301 gtggttcagg tcatactgta actgatgata tagatcactt cttttcagca ccatcaataa
     3361 catatagaga gccacactta tctatatatg acgtattgga agtacaaaaa gaagaacttg
     3421 atttgtcaaa agatttaatg gtattaccta atgctccaaa tagagtattt gcttgggaaa
     3481 caggatggac accaggttta agaagcttag aaaatgatgg cacaaaactg ttagaccgta
     3541 taagagataa ctatgaaggt gagttttatt ggagatattt tgcttttata gctgatgctt
     3601 taataacaac attaaaacca agatatgaag atactaatat aagaataaat ttagatagta
     3661 atactagaag ttttatagtt ccaataataa ctacagaata tataagagaa aaattatcat
     3721 attctttcta tggttcagga ggaacttatg cattgtctct ttctcaatat aatatgggta
     3781 taaatataga attaagtgaa agtgatgttt ggattataga tgttgataat gttgtgagag
     3841 atgtaactat agaatctgat aaaattaaaa aaggtgattt aatagaaggt attttatcta
     3901 cactaagtat tgaagagaat aaaattatct taaatagcca tgagattaat ttttctggtg
     3961 aggtaaatgg aagtaatgga tttgtttctt taacattttc aattttagaa ggaataaatg
     4021 caattataga agttgattta ttatctaaat catataaatt acttatttct ggcgaattaa
     4081 aaatattgat gttaaattca aatcatattc aacagaaaat agattatata ggattcaata
     4141 gcgaattaca gaaaaatata ccatatagct ttgtagatag tgaaggaaaa gagaatggtt
     4201 ttattaatgg ttcaacaaaa gaaggtttat ttgtatctga attacctgat gtagttctta
     4261 taagtaaggt ttatatggat gatagtaagc cttcatttgg atattatagt aataatttga
     4321 aagatgtcaa agttataact aaagataatg ttaatatatt aacaggttat tatcttaagg
     4381 atgatataaa aatctctctt tctttgactc tacaagatga aaaaactata aagttaaata
     4441 gtgtgcattt agatgaaagt ggagtagctg agattttgaa gttcatgaat agaaaaggta
     4501 atacaaatac ttcagattct ttaatgagct ttttagaaag tatgaatata aaaagtattt
     4561 tcgttaattt cttacaatct aatattaagt ttatattaga tgctaatttt ataataagtg
     4621 gtactacttc tattggccaa tttgagttta tttgtgatga aaatgataat atacaaccat
     4681 atttcattaa gtttaataca ctagaaacta attatacttt atatgtagga aatagacaaa
     4741 atatgatagt ggaaccaaat tatgatttag atgattctgg agatatatct tcaactgtta
     4801 tcaatttctc tcaaaagtat ctttatggaa tagacagttg tgttaataaa gttgtaattt
     4861 caccaaatat ttatacagat gaaataaata taacgcctgt atatgaaaca aataatactt
     4921 atccagaagt tattgtatta gatgcaaatt atataaatga aaaaataaat gttaatatca
     4981 atgatctatc tatacgatat gtatggagta atgatggtaa tgattttatt cttatgtcaa
     5041 ctagtgaaga aaataaggtg tcacaagtta aaataagatt cgttaatgtt tttaaagata
     5101 agactttggc aaataagcta tcttttaact ttagtgataa acaagatgta cctgtaagtg
     5161 aaataatctt atcatttaca ccttcatatt atgaggatgg attgattggc tatgatttgg
     5221 gtctagtttc tttatataat gagaaatttt atattaataa ctttggaatg atggtatctg
     5281 gattaatata tattaatgat tcattatatt attttaaacc accagtaaat aatttgataa
     5341 ctggatttgt gactgtaggc gatgataaat actactttaa tccaattaat ggtggagctg
     5401 cttcaattgg agagacaata attgatgaca aaaattatta tttcaaccaa agtggagtgt
     5461 tacaaacagg tgtatttagt acagaagatg gatttaaata ttttgcccca gctaatacac
     5521 ttgatgaaaa cctagaagga gaagcaattg attttactgg aaaattaatt attgacgaaa
     5581 atatttatta ttttgatgat aattatagag gagctgtaga atggaaagaa ttagatggtg
     5641 aaatgcacta ttttagccca gaaacaggta aagcttttaa aggtctaaat caaataggtg
     5701 attataaata ctatttcaat tctgatggag ttatgcaaaa aggatttgtt agtataaatg
     5761 ataataaaca ctattttgat gattctggtg ttatgaaagt aggttacact gaaatagatg
     5821 gcaagcattt ctactttgct gaaaacggag aaatgcaaat aggagtattt aatacagaag
     5881 atggatttaa atattttgct catcataatg aagatttagg aaatgaagaa ggtgaagaaa
     5941 tctcatattc tggtatatta aatttcaata ataaaattta ctattttgat gattcattta
     6001 cagctgtagt tggatggaaa gatttagagg atggttcaaa gtattatttt gatgaagata
     6061 cagcagaagc atatataggt ttgtcattaa taaatgatgg tcaatattat tttaatgatg
     6121 atggaattat gcaagttgga tttgtcacta taaatgataa agtcttctac ttctctgact
     6181 ctggaattat agaatctgga gtacaaaaca tagatgacaa ttatttctat atagatgata
     6241 atggtatagt tcaaattggt gtatttgata cttcagatgg atataaatat tttgcacctg
     6301 ctaatactgt aaatgataat atttacggac aagcagttga atatagtggt ttagttagag
     6361 ttggggaaga tgtatattat tttggagaaa catatacaat tgagactgga tggatatatg
     6421 atatggaaaa tgaaagtgat aaatattatt tcaatccaga aactaaaaaa gcatgcaaag
     6481 gtattaattt aattgatgat ataaaatatt attttgatga gaagggcata atgagaacgg
     6541 gtcttatatc atttgaaaat aataattatt actttaatga gaatggtgaa atgcaatttg
     6601 gttatataaa tatagaagat aagatgttct attttggtga agatggtgtc atgcagattg
     6661 gagtatttaa tacaccagat ggatttaaat actttgcaca tcaaaatact ttggatgaga
     6721 attttgaggg agaatcaata aactatactg gttggttaga tttagatgaa aagagatatt
     6781 attttacaga tgaatatatt gcagcaactg gttcagttat tattgatggt gaggagtatt
     6841 attttgatcc tgatacagct caattagtga ttagtgaata gataaaaata tgttaaatat
     6901 atcctcttat acttaaatat ataaaaataa acaaaatgat acactacata aagtgttcta
     6961 tctaatatga agatttacca ataaaaaggt ggactatgat gaatgcacag tagttcacct
     7021 ttttatattt ctaatggtaa caaaatattt ttttatataa acctaggagg cgttatgaat
     7081 atgacaatat cttttttatc agagcatata tttataaagt tagtaatttt aactatatca
     7141 tttgatacat tattaggatg tttaagtgca ataaaaagtc gtaaatttaa ttctagtttt
     7201 ggaatagatg gaggaatcag aaaagtagca atgatagcat gtatattttt tttatcagta
     7261 gttgacattc ttacaaagtt taacttttta tttatgttac cacaagattg tatcaatttt
     7321 ttaagactaa aacatcttgg aatatctgaa tttttctcta ttttatttat tttatatgaa
     7381 agtgtaagta tattaaaaaa tatgtgctta tgtggattac cagtacctaa gagattaaag
     7441 gaaaaaatag caattttact agatgcaatg acagatgaaa tgaatgctaa ggatgaaaag
     7501 taagtaatgg tagatataat aaagatatta acaaataaaa agtgttatcc aaataagaat
     7561 agctgaaagt tatcataatt catgaaacta ataatgaaaa cgagggagca gatgccaaga
     7621 gacacacaag tattaaatac atataatttc gaagcaagtg ttcattacta tatagatgac
     7681 aaggtagtat atcaaacatt ggttcacaaa gatggtgcat ggtcagttgg taaaatctat
     7741 taagctacat tagttacaga tatcacaaac tataatagtt aaacatagaa atatgtgtaa
     7801 attgtgatgg aaattattca aaaacacaaa aatacgtgat gaaggacaaa atgatataga
     7861 aaataagtat caaaccttaa taaatgattt aattgatagt ttaaaagtta taggaaaaat
     7921 atataaagaa ataaaaacat taaaaaaata taagatatgt ttacaaatta ctatcagaca
     7981 atctccttat ctaatagaag agtcaattaa ctaattgagt atctttaaat tgaaatgtta
     8041 ggaagtgatt taaatatgaa aacttaaatt ataaaaaatc aatattaatt tatttttaaa
     8101 aaatagaaag gagtgtataa gatttatttt caaagtttaa aaacaagaaa atcaatttaa
     8161 atttcagaag gaataaatgt ggttatagaa gtggatttat tatcaaaaat aataatacta
     8221 ggaggttttt atgtctttaa tatctaaaga agagttaata aaactcgcat atagcattag
     8281 accaagagaa aatgagtata aaactatact aactaattta gacgaatata ataagttaac
     8341 tacaaacaat aatgaaaata aatatttaca attaaaaaaa ctaaatgaat caattgatgt
     8401 ttttatgaat aaatataaaa cttcaagcag aaatagagca ctctctaatc taaaaaaaga
     8461 tatattaaaa gaagtaattc ttattaaaaa ttccaataca agccctgtag aaaaaaattt
     8521 acattttgta tggataggtg gagaagtcag tgatattgct cttgaataca taaaacaatg
     8581 ggctgatatt aatgcagaat ataatattaa actgtggtat gatagtgaag cattcttagt
     8641 aaatacacta aaaaaggcta tagttgaatc ttctaccact gaagcattac agctactaga
     8701 ggaagagatt caaaatcctc aatttgataa tatgaaattt tacaaaaaaa ggatggaatt
     8761 tatatatgat agacaaaaaa ggtttataaa ttattataaa tctcaaatca ataaacctac
     8821 agtacctaca atagatgata ttataaagtc tcatctagta tctgaatata atagagatga
     8881 aactgtatta gaatcatata gaacaaattc tttgagaaaa ataaatagta atcatggtat
     8941 agatatcagg gctaatagtt tgtttacaga acaagagtta ttaaatattt atagtcagga
     9001 gttgttaaat cgtggaaatt tagctgcagc atctgacata gtaagattat tagccctaaa
     9061 aaattttggc ggagtatatt tagatgttga tatgcttcca ggtattcact ctgatttatt
     9121 taaaacaata tctagaccta gctctattgg actagaccgt tgggaaatga taaaattaga
     9181 ggctattatg aagtataaaa aatatataaa taattataca tcagaaaact ttgataaact
     9241 tgatcaacaa ttaaaagata attttaaact cattatagaa agtaaaagtg aaaaatctga
     9301 gatattttct aaattagaaa atttaaatgt atctgatctt gaaattaaaa tagctttcgc
     9361 tttaggcagt gttataaatc aagccttgat atcaaaacaa ggttcatatc ttactaacct
     9421 agtaatagaa caagtaaaaa atagatatca atttttaaac caacacctta acccagccat
     9481 agagtctgat aataacttca cagatactac taaaattttt catgattcat tatttaattc
     9541 agctaccgca gaaaactcta tgtttttaac aaaaatagca ccatacttac aagtaggttt
     9601 tatgccagaa gctcgctcca caataagttt aagtggtcca ggagcttatg cgtcagctta
     9661 ctatgatttc ataaatttac aagaaaatac tatagaaaaa actttaaaag catcagattt
     9721 aatagaattt aaattcccag aaaataatct atctcaattg acagaacaag aaataaatag
     9781 tctatggagc tttgatcaag caagtgcaaa atatcaattt gagaaatatg taagagatta
     9841 tactggtgga tctctttctg aagacaatgg ggtagacttt aataaaaata ctgccctcga
     9901 caaaaactat ttattaaata ataaaattcc atcaaacaat gtagaagaag ctggaagtaa
     9961 aaattatgtt cattatatca tacagttaca aggagatgat ataagttatg aagcaacatg
    10021 caatttattt tctaaaaatc ctaaaaatag tattattata caacgaaata tgaatgaaag
    10081 tgcaaaaagc tactttttaa gtgatgatgg agaatctatt ttagaattaa ataaatatag
    10141 gatacctgaa agattaaaaa ataaggaaaa agtaaaagta acctttattg gacatggtaa
    10201 agatgaattc aacacaagcg aatttgctag attaagtgta gattcacttt ccaatgagat
    10261 aagttcattt ttagatacca taaaattaga tatatcacct aaaaatgtag aagtaaactt
    10321 acttggatgt aatatgttta gttatgattt taatgttgaa gaaacttatc ctgggaagtt
    10381 gctattaagt attatggaca aaattacttc cactttacct gatgtaaata aaaattctat
    10441 tactatagga gcaaatcaat atgaagtaag aattaatagt gagggaagaa aagaacttct
    10501 ggctcactca ggtaaatgga taaataaaga agaagctatt atgagcgatt tatctagtaa
    10561 agaatacatt ttttttgatt ctatagataa taagctaaaa gcaaagtcca agaatattcc
    10621 aggattagca tcaatatcag aagatataaa aacattatta cttgatgcaa gtgttagtcc
    10681 tgatacaaaa tttattttaa ataatcttaa gcttaatatt gaatcttcta ttggtgatta
    10741 catttattat gaaaaattag agcctgttaa aaatataatt cacaattcta tagatgattt
    10801 aatagatgag ttcaatctac ttgaaaatgt atctgatgaa ttatatgaat taaaaaaatt
    10861 aaataatcta gatgagaagt atttaatatc ttttgaagat atctcaaaaa ataattcaac
    10921 ttactctgta agatttatta acaaaagtaa tggtgagtca gtttatgtag aaacagaaaa
    10981 agaaattttt tcaaaatata gcgaacatat tacaaaagaa ataagtacta taaagaatag
    11041 tataattaca gatgttaatg gtaatttatt ggataatata cagttagatc atacttctca
    11101 agttaataca ttaaacgcag cattctttat tcaatcatta atagattata gtagcaataa
    11161 agatgtactg aatgatttaa gtacctcagt taaggttcaa ctttatgctc aactatttag
    11221 tacaggttta aatactatat atgactctat ccaattagta aatttaatat caaatgcagt
    11281 aaatgatact ataaatgtac tacctacaat aacagagggg atacctattg tatctactat
    11341 attagacgga ataaacttag gtgcagcaat taaggaatta ctagacgaac atgacccatt
    11401 actaaaaaaa gaattagaag ctaaggtggg tgttttagca ataaatatgt cattatctat
    11461 agctgcaact gtagcttcaa ttgttggaat aggtgctgaa gttactattt tcttattacc
    11521 tatagctggt atatctgcag gaataccttc attagttaat aatgaattaa tattgcatga
    11581 taaggcaact tcagtggtaa actattttaa tcatttgtct gaatctaaaa aatatggccc
    11641 tcttaaaaca gaagatgata aaattttagt tcctattgat gatttagtaa tatcagaaat
    11701 agattttaat aataattcga taaaactagg aacatgtaat atattagcaa tggagggggg
    11761 atcaggacac acagtgactg gtaatataga tcactttttc tcatctccat ctataagttc
    11821 tcatattcct tcattatcaa tttattctgc aataggtata gaaacagaaa atctagattt
    11881 ttcaaaaaaa ataatgatgt tacctaatgc tccttcaaga gtgttttggt gggaaactgg
    11941 agcagttcca ggtttaagat cattggaaaa tgacggaact agattacttg attcaataag
    12001 agatttatac ccaggtaaat tttactggag attctatgct tttttcgatt atgcaataac
    12061 tacattaaaa ccagtttatg aagacactaa tattaaaatt aaactagata aagatactag
    12121 aaacttcata atgccaacta taactactaa cgaaattaga aacaaattat cttattcatt
    12181 tgatggagca ggaggaactt actctttatt attatcttca tatccaatat caacgaatat
    12241 aaatttatct aaagatgatt tatggatatt taatattgat aatgaagtaa gagaaatatc
    12301 tatagaaaat ggtactatta aaaaaggaaa gttaataaaa gatgttttaa gtaaaattga
    12361 tataaataaa aataaactta ttataggcaa tcaaacaata gatttttcag gcgatataga
    12421 taataaagat agatatatat tcttgacttg tgagttagat gataaaatta gtttaataat
    12481 agaaataaat cttgttgcaa aatcttatag tttgttattg tctggggata aaaattattt
    12541 gatatccaat ttatctaata ctattgagaa aatcaatact ttaggcctag atagtaaaaa
    12601 tatagcgtac aattacactg atgaatctaa taataaatat tttggagcta tatctaaaac
    12661 aagtcaaaaa agcataatac attataaaaa agacagtaaa aatatattag aattttataa
    12721 tgacagtaca ttagaattta acagtaaaga ttttattgct gaagatataa atgtatttat
    12781 gaaagatgat attaatacta taacaggaaa atactatgtt gataataata ctgataaaag
    12841 tatagatttc tctatttctt tagttagtaa aaatcaagta aaagtaaatg gattatattt
    12901 aaatgaatcc gtatactcat cttaccttga ttttgtgaaa aattcagatg gacaccataa
    12961 tacttctaat tttatgaatt tatttttgga caatataagt ttctggaaat tgtttgggtt
    13021 tgaaaatata aattttgtaa tcgataaata ctttaccctt gttggtaaaa ctaatcttgg
    13081 atatgtagaa tttatttgtg acaataataa aaatatagat atatattttg gtgaatggaa
    13141 aacatcgtca tctaaaagca ctatatttag cggaaatggt agaaatgttg tagtagagcc
    13201 tatatataat cctgatacgg gtgaagatat atctacttca ctagattttt cctatgaacc
    13261 tctctatgga atagatagat atatcaataa agtattgata gcacctgatt tatatacaag
    13321 tttaataaat attaatacca attattattc aaatgagtac taccctgaga ttatagttct
    13381 taacccaaat acattccaca aaaaagtaaa tataaattta gatagttctt cttttgagta
    13441 taaatggtct acagaaggaa gtgactttat tttagttaga tacttagaag aaagtaataa
    13501 aaaaatatta caaaaaataa gaatcaaagg tatcttatct aatactcaat catttaataa
    13561 aatgagtata gattttaaag atattaaaaa actatcatta ggatatataa tgagtaattt
    13621 taaatcattt aattctgaaa atgaattaga tagagatcat ttaggattta aaataataga
    13681 taataaaact tattactatg atgaagatag taaattagtt aaaggattaa tcaatataaa
    13741 taattcatta ttctattttg atcctataga atttaactta gtaactggat ggcaaactat
    13801 caatggtaaa aaatattatt ttgatataaa tactggagca gctttaacta gttataaaat
    13861 tattaatggt aaacactttt attttaataa tgatggtgtg atgcagttgg gagtatttaa
    13921 aggacctgat ggatttgaat attttgcacc tgccaatact caaaataata acatagaagg
    13981 tcaggctata gtttatcaaa gtaaattctt aactttgaat ggcaaaaaat attattttga
    14041 taatgactca aaagcagtca ctggatggag aattattaac aatgagaaat attactttaa
    14101 tcctaataat gctattgctg cagtcggatt gcaagtaatt gacaataata agtattattt
    14161 caatcctgac actgctatca tctcaaaagg ttggcagact gttaatggta gtagatacta
    14221 ctttgatact gataccgcta ttgcctttaa tggttataaa actattgatg gtaaacactt
    14281 ttattttgat agtgattgtg tagtgaaaat aggtgtgttt agtacctcta atggatttga
    14341 atattttgca cctgctaata cttataataa taacatagaa ggtcaggcta tagtttatca
    14401 aagtaaattc ttaactttga atggtaaaaa atattacttt gataataact caaaagcagt
    14461 taccggatgg caaactattg atagtaaaaa atattacttt aatactaaca ctgctgaagc
    14521 agctactgga tggcaaacta ttgatggtaa aaaatattac tttaatacta acactgctga
    14581 agcagctact ggatggcaaa ctattgatgg taaaaaatat tactttaata ctaacactgc
    14641 tatagcttca actggttata caattattaa tggtaaacat ttttatttta atactgatgg
    14701 tattatgcag ataggagtgt ttaaaggacc taatggattt gaatattttg cacctgctaa
    14761 tacggatgct aacaacatag aaggtcaagc tatactttac caaaatgaat tcttaacttt
    14821 gaatggtaaa aaatattact ttggtagtga ctcaaaagca gttactggat ggagaattat
    14881 taacaataag aaatattact ttaatcctaa taatgctatt gctgcaattc atctatgcac
    14941 tataaataat gacaagtatt actttagtta tgatggaatt cttcaaaatg gatatattac
    15001 tattgaaaga aataatttct attttgatgc taataatgaa tctaaaatgg taacaggagt
    15061 atttaaagga cctaatggat ttgagtattt tgcacctgct aatactcaca ataataacat
    15121 agaaggtcag gctatagttt accagaacaa attcttaact ttgaatggca aaaaatatta
    15181 ttttgataat gactcaaaag cagttactgg atggcaaacc attgatggta aaaaatatta
    15241 ctttaatctt aacactgctg aagcagctac tggatggcaa actattgatg gtaaaaaata
    15301 ttactttaat cttaacactg ctgaagcagc tactggatgg caaactattg atggtaaaaa
    15361 atattacttt aatactaaca ctttcatagc ctcaactggt tatacaagta ttaatggtaa
    15421 acatttttat tttaatactg atggtattat gcagatagga gtgtttaaag gacctaatgg
    15481 atttgaatac tttgcacctg ctaatactca taataataac atagaaggtc aagctatact
    15541 ttaccaaaat aaattcttaa ctttgaatgg taaaaaatat tactttggta gtgactcaaa
    15601 agcagttacc ggattgcgaa ctattgatgg taaaaaatat tactttaata ctaacactgc
    15661 tgttgcagtt actggatggc aaactattaa tggtaaaaaa tactacttta atactaacac
    15721 ttctatagct tcaactggtt atacaattat tagtggtaaa catttttatt ttaatactga
    15781 tggtattatg cagataggag tgtttaaagg acctgatgga tttgaatact ttgcacctgc
    15841 taatacagat gctaacaata tagaaggtca agctatacgt tatcaaaata gattcctata
    15901 tttacatgac aatatatatt attttggtaa taattcaaaa gcggctactg gttgggtaac
    15961 tattgatggt aatagatatt acttcgagcc taatacagct atgggtgcga atggttataa
    16021 aactattgat aataaaaatt tttactttag aaatggttta cctcagatag gggtgtttaa
    16081 agggtctaat ggatttgaat actttgcacc tgctaatacg gatgctaaca atatagaagg
    16141 tcaagctata cgttatcaaa atagattcct acatttactt ggaaaaatat attactttgg
    16201 taataattca aaagcagtta ctggatggca aactattaat ggtaaagtat attactttat
    16261 gcctgatact gctatggctg cagctggtgg actttttgag attgatggtg ttatatattt
    16321 ctttggtgtt gatggagtaa aagcccctgg gatatatggc taaaatatat gtttgataaa
    16381 aaattattcc tgtgctacta agaaattatt tttatataat aaatattgag atttaattaa
    16441 aagtcatgtg ttattgtaat acatgacttt tagttaaaat ttttctatca tttaataatc
    16501 tattattctt gactatttta taataaaatt catatatgga aatattaata ctaaataatt
    16561 aatagttgat aaaaaataga taatatgcta aaagcaaaaa ctaatttaga gccttgtaac
    16621 tgtttatttg caattataaa aacatcttta aacatattga ctataatata aaatattaac
    16681 tataatacaa aacaatatta attaattttc tctacagcta tccctggtat agttatattt
    16741 ccacccatag ttgattcata agttatagtt ccagcactta tacctcttat agttatgtaa
    16801 tcatcctcta atactcttga aggagttatt gattttttat aactacatag tacaacctta
    16861 tcataatttc cagacacagc taatcttatt tgcacctcat caccatcttc aataacttga
    16921 ataaccttac cttcaaattt tacctttttg tacttataat catcaggtgt tctagctaat
    16981 tggtcataag taataccagt atcatatcct ttcttctcct cttcttcttt tttgcgttgt
    17041 tcttcagcct ttttagcttc ttcagctttt ttagcttctt cagctttacg ttgattttca
    17101 gcttcaatag ctttcttttc gtcgtctttc attttgaacc atggttcagc atcagacaat
    17161 ttgctattta aagtttctat ttctgttttt tgagaatcta taactgatgt ttggttagaa
    17221 atgacctcct catggtcttc agaacaagct ggtgaggata tattgccaaa aaacacgcct
    17281 aaaataaatg ccagtagagc aatacccttt gtgctcttaa agaatttaat tattttctta
    17341 gagcttcctt ttccttcatt actaaattcg ttaccatcat tttttttaga aaacataata
    17401 caatctccct tttattagat atattttatt ttaaaagtta aaaacttaaa ataactagtt
    17461 gactaaaaat tatatattca tattttccta aaatatattt cccctaagca taattttaca
    17521 aaataaagta agaagattca atatattttg aaaaaataag ataaaaatgt cagattataa
    17581 tataattttc ttgaaggtga attttatata ttaaattaaa cataaagtat tttatttgta
    17641 taaaactata ttatgatgta attaagtgac tcagtgattt agaggtggta aaatatatat
    17701 atatgaaaga gcataaataa attgatataa taaaaaatta aatattaaat attaactata
    17761 ataaaaaaat atctggtaat aggtataata taaaaagaat ataccagaaa gaaggtgaag
    17821 tatgggagaa ctacaaaaaa ttccaggggt agggaaagca acagaaaaat ctttaatcat
    17881 gttaggatat acaactatta aatcacttaa agatgcaaac ccagcacaaa tgtatgaaaa
    17941 ggaatgttta atacgtggac agcacataga cagatgtcag ttatatgtat acagatgtgc
    18001 agtatatttt gcatcaactg aaaatccaga accagaaaaa ttaaagtggt ggtattggaa
    18061 agattaaaaa atcaaaaaag ttagacataa aaaagagttg aatatccgtt ttaaataata
    18121 aaaactaata ctcaactctt ttttagtcgt aaattttatg taaatctatt tgtatggcta
    18181 aatataccca tcaataaatg tataaatata ccaatcaaca aatgactaaa catactacct
    18241 aacaaaggat taaataaatt acttaacaaa gcattctaaa acaattaatt agaaactgtt
    18301 tcttcaagcc attttctaca ttgctcaata tttaccatag ggtcaaaacc ttggtctttt
    18361 cccttattta aaagcatatc acaagggaaa gtatcacatt caccacaatg attaagttcc
    18421 ttactttcac agcaagtttt aaccttacat tctccacccc aaaatggttt ttccatagtt
    18481 gggcaaccag tgcaatttac ttgttctttt tttgtacaac tgtcacaaca gacaccacat
    18541 cttgattcaa acatgttcaa acatcctttc cattatttaa aaatattata aaatgatttt
    18601 agatgaatac aaaagtgcaa atagttgatt ttaggtcatc taaatgttaa acataaaatt
    18661 attagtactg gtaaatttat aaaaactatt ccaaaaatct ttttgaatat ttcaaaacac
    18721 aataaattac ttcaaatccc tttgaatata ttttacagca ttatagattg ctttaaatct
    18781 ctttgaatat tctacaagac tatagattag tttaaatccc tttgaatata ttttacaaca
    18841 ttatagattg ttttaaatct ctttgaatat tctacaagac tatagattag tttaaatccc
    18901 tttgaatatt tcaaaacacc atagattact ttaaatccct ttgaatattc tataacacta
    18961 taaattactt ttaactttta tataaccata aagtttttat ctggcacttt aaatggagtt
    19021 ttatatcaaa tttgccttcc atcgaataac caaacttaat ttaattacac attccaagag
    19081 tcaaatattc attcaatata tttgataatt ctatgttata gctataatta aatatagatt
    19141 attaaagtta aatatttatt taatatattg aatgattttt tacctatatt taattaagtt
    19201 tcattatata atataaaaat tgtttttgca ttaagtttta atataataca taataatttt
    19261 aaataataac attattatat attttttaat tttaggagta tatctattat atagcgagta
    19321 gataaaacat ataaaattca aataaaagat atatattttt aaataaaatg gatatagatt
    19381 tcaactaaaa agaatataaa tttcaaaccc caaaatatct agcatttacc attaagaaat
    19441 aacatcattc tttctaaaat ttctattggc aatttcagaa aatactatag tagtaataaa
    19501 tgcaacacat attgtaacta tagtgtcatt aacatttaaa gcagattgct ttataacccc
    19561 catagcacta cctaacatag aataagggaa aaatatacca acagcaggtt ttgctactat
    19621 taatcccata ccaaatagag aaaggcaaag actaatacca ataggagttg caaaacttct
    19681 aatctttata gacatgtata attgtataga agctattgaa atagaaataa tccaaccttt
    19741 agcaatccaa ccagtcaatt ctttaggtac actaccagaa aaaccaaaca tatttcctgc
    19801 aactatataa aagataacaa agaaaacttg tgtaatagct gtaagtattg aaactactgt
    19861 aagtttagat aaaaagatat tttttaaatt aactggcagt gtcattacat tattccaatt
    19921 atgattcata tgttcaagcc tacaaatata tgcacaaaag attgcgatta agataggaaa
    19981 gaaaaattcc ccataaaaaa gactaacttg agtccataag ctgtaccatt cttttttgag
    20041 tatgccttga tttagataaa aattaccaga accaatcaac acacttataa gtggcaaagc
    20101 taataataca taccatataa aagaattttt taactttaga atttctccca aaactgactt
    20161 ccttaacatt taaatccctc ctatacttct ttttttaata aatgatttct tccaatataa
    20221 taaattagca ttccaattaa gaaaactaaa atcgtaatag aaaaattcat atcaattcta
    20281 tagacagatg aacctaaaac attatcataa gcataactta aaggtgataa ctctaggtaa
    20341 taagaccata taaacaatct acgaatacct tgataaaaca aacctgatgt caaacctata
    20401 aaactaccaa tcatgccaaa tgtaattgca atcatttgat ttggaattac agttgcaatc
    20461 cataggtgta gtgcaatgat agcaatactt acaagaattg ttcctaatgt gtattttaaa
    20521 agtaaagata cagaaattga ctcaataacc cctctaaaat gtccaaacaa cacaatagat
    20581 aacacttgca tcaatacagg tatagatacc aaaatagcag aacataaaaa tttagataaa
    20641 taaatactat ttaaagatgt cacagaagat tttaaaagct tccatgtatc tcctttatgt
    20701 tctatatcgc ttatacgtga tgtaattatt gatattaaga taggaaagaa tagaccattt
    20761 aaacttgcaa aactcataaa catataggaa tattcaaatc cacctaacat atctggatta
    20821 cgtgtaatag ctctatttga atttatgata caccacatta tttcaacagc tacaaataaa
    20881 aaggtcatca gaataatctt ctttctttta agtttataaa attctagacc aaggtatttc
    20941 attataaagt caccgcctta ccagtaagtt ctaagaatat atcttccaag ctttttttat
    21001 gttcttctat tctaaataca tctatatttg aatggacaag cataccattt attttagcca
    21061 catctgagtc ttttaaattt tcaatagtca agtacccatc ttgtataagt gacatatatc
    21121 ctttagtatt taatagtttt tgtgcagata caacattctt agttttgata gcaatctgac
    21181 tttgacctct attatgaagt tcttttatgc tatcttgaaa aaccagttcg ccatgattta
    21241 ttattcctat tgatgtggca atttggtcaa tttcacttaa aagatggcta gagattagaa
    21301 cagtcatccc gtatttttct ggtagagatt ttattaattc tctaatttcc tcaatccctg
    21361 ctgggtcgag tccatttgta ggttcatcaa gtattaataa tttgggaaac ttcattattg
    21421 ccatagcaat accaagacgt tgcttcatac ctaaagaata ttgactaact tttttatttt
    21481 tttgattttc taaccttaca atttttaatg cttcatttac atttttttta ggtaaatcta
    21541 agagtttttg cattatggtc atgttttcaa gccctgtaag atgaccatag tatgatggag
    21601 attctatcaa agaacctata tcttttaaaa ttgatattct atttttttca tttaactctt
    21661 tacctaaaat attaatattt ccttgtgtgg gtttagcaag tccaagaagc attttaagag
    21721 tggtagattt tccagctcca ttaggaccca aaaaaccata tacagctcct tgtggaactc
    21781 ttaggtctat atcctttact ctaaatattt tattgtattc ctttgaaagt ctttgtgttc
    21841 taattatcat ttccatatgt ttcatcccct tttttaatct gtgcttattg attcttttaa
    21901 cttatatcag tataataact tggttacatt tcaattagct gaaatttacc ttacaataac
    21961 cttaaaagtc tatttaggca aagttgtgaa aatgggtata tggtatacta aaggagggtg
    22021 atgattatgg agtcaataaa agataaaaaa atacttgtgg ttgatgacca caaggaatta
    22081 ttaaaaatga tagatgaaat cctgagaaaa gaggggttta gtagagtatt tttagcatca
    22141 agttatgagg aagctgttag ggtatttaga aatgtaaagc cagattgtgc aattttagat
    22201 gttgtattgc cagatggaga tggtttttct attatgagaa aaattagaga gacatctaaa
    22261 ataccagtga tttttctctc tgcaagaggt gaagatgaag atagattgat tggtttgggc
    22321 ttaggggctg acgattatat agtaaagcca tttttaccaa aggaacttac tttaaggctt
    22381 gtgggtatat taaatcgtgt atatgtgcct atagaagaag aggagttgcc agtatttaaa
    22441 ctgggagatt ctgttgttgt gaatttaaat agtgcatgtg ttgagaaaga tgggcaagag
    22501 atttctttaa cagctaaaga gcattcgttg cttttaaagt tgtatgaaaa taaagggaga
    22561 attgttacta atgattcact atgtcaagcc atttggggag atgatatgta tggatatgaa
    22621 aataccctta tggttcatgt tagaagggtt agagagaaga tagaaaaaac tccatctaca
    22681 cctaaacatc ttattacagt aagaggtctt ggatataagt tgatgattaa ttaattttag
    22741 atattagaat aaaagaaatc aagaggagtg atttaatttt ggatagtgta aagtacatat
    22801 tgaggcgatt tataggttca agtatcttga tttcattact ttttattgta ttaaatatag
    22861 caggttttct tctgttttca tatatgctat ttgtatctaa atactctgat aatttagata
    22921 caagtgatag cagagaaata aaatcaaact tgattatgat tgaagataat ttgattttaa
    22981 gaaatggaaa gtttatttta gatgattcta gtaaggaagt actacataaa aataaagttt
    23041 gggcaatgtt aattgataac aatggagata gaatatgggg atttgattta ccaaaagaaa
    23101 ttccaagtca ttatactttg acagatgtag caaagttttc aaggttcttt ttaaaggact
    23161 atcctgtgta tgtatgggaa catccaaatg gaatattagt aacaggttat ccaaaagaca
    23221 agtacactaa gtttaacctt acttatacgg ttaaggaaat agaacaattt cctatgttaa
    23281 taataggtat gtttttggtt aatgcaatag ttactttttt aatagctcta ttcataggtt
    23341 taaaaatggt gaaatctata aaaccaatta ttactggcat aaagcttatg tcaaaaggag
    23401 aaccagtact tttacaagaa aaaggaatac taagtgatat ttcaaaatct attaatactg
    23461 tatctaaaga gttgcaaatg aaagatgaaa aacttaggaa gaaagaggaa gctaggtcta
    23521 actggattgc aggaatatct catgatataa gaactccact ttcaatgata attggatatg
    23581 ctggagaact tgaagaaagc agtagccttt caaatagaga acaagagcaa gtgtctatta
    23641 tatgcaatca agggattaaa atcagagaat tagtaaatga cctaaattta gtgtctaaac
    23701 ttgaatataa tatgcaagca ttgaattgtg ataagattag agtttctgcg tttttgagag
    23761 agcttatttc tgagtttata aataataatt tggataatga cttttacgtt gaatttgata
    23821 tactaaatga agatattatt atagatgcag ataaaaaatt attaaaaagg gctattagta
    23881 atttaataca aaatagtata actcataacc aacaaggatg taatataagg gttacctcta
    23941 agtctgattt agatttttgc tatataattg ttgaagatga tggaaaaggt atgagtcaag
    24001 aaagaattaa tagtttatta aagagccaaa atggactaag tgaggcatat gccaaaggtc
    24061 aaaatcatgg tctaggtatt ttgatagtat ctggcattat taatgcacat agaggtaaat
    24121 tagatattac gagcattgat agtcagggac taaaaacaat actaaaatta cctctaatta
    24181 agtgatattt tataaaataa taacagataa gaatgaagaa tgaaaatatt ttgaaaataa
    24241 ttttattctt tattgacaaa ttaactctat tagagtagaa taaggataaa ttcttttctt
    24301 gtcaagtttt attaaagtaa agagtaactt gtgctttatg cgcttatggc tgagttactc
    24361 atggtatcaa aattttcata gaaataatat tttggaatta ttgtaaggtt attaaattct
    24421 ttagataatt ccattttttt tattttttag ttaatattta attttattat tgacaaaaaa
    24481 attctactaa aatagaatta tggtatagtg ttttttaatt ttaagaaaaa atataatgac
    24541 atcctaaaaa agttttaatt atacgctgtt ctgtgtagtt ataatagctt ctatgtaact
    24601 attgtaagta tattattata gttatttatt taaagtacga taaatgtttt aaattgaagt
    24661 attttgcgcc attgagttct actaaagtag agtttttgtg tagtattttt agaaataaca
    24721 tatatatata tgtatttatg ttgaaatata tgggaaattt ataatataat taatgaaaaa
    24781 atttaaactt tgtaatatat aaataaaaaa actctaaaat agaaggatat aattatatag
    24841 aatgtttcaa ttaaacaagg caaaaactat aatcttaaaa ttaacattat tcttaagaag
    24901 taagaaattt aagaagtaaa aagtttagtt ataagtggta gtaagcaaga aatttaagaa
    24961 gtaaaaagtt tagttataag tggtagtaag caagaaattt aggaagtggg aagtttagtt
    25021 ataagtggta gtaagtaaga aatttaggaa gtgggaagtt tagttataag tagtagtaag
    25081 taagaaattt aggaagtggg aagtttagtt ataagtagta gtaagtaaga aatttaggaa
    25141 gtaggaagtt tagtaataat ttgtagcaag taagaaactt aggaagtggg aagtttagta
    25201 gtaataattt atagcaagta agaaatttag gaagtaggaa gtttagtaat aatttgtagc
    25261 aagtaagaaa tttagaaagt aggaagttta gtaataattt atagcaagta agaaatttag
    25321 ggagtaggaa gtttagtaat aatttatagc aagtaagaaa tttagggagt aggaagttta
    25381 gtaataattt gtatcaagta agaaatttag ggagtaggaa gtttagtaat aatttatagc
    25441 aagtaagaaa tttagaaagt aggaagttta gtaataattt a
//
LOCUS       DAJMZY010000054        25061 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.054, whole genome shotgun sequence.
ACCESSION   DAJMZY010000054 DAJMZY010000000
VERSION     DAJMZY010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 25061)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25061)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25061
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.054"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            complement(<1..1282)
                     /locus_tag="OE968_002132"
     CDS             complement(<1..1282)
                     /locus_tag="OE968_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HCP7219411.1"
                     /translation="MLLSIVMIVKNEEKILEKTLKSLTTLRNSIESELIIVDTGSTDD
                     TIKISKKYTEKVYFHNWNNDFSSMRNISISYAKGEWLLILDADEILIDSSTIVKFFKD
                     GLDKKFNSASIQLKNLYSYDKKLYGYCSVLRLFKNVDFRYHGKVHEQPIYKNPIFNNV
                     ADFEHYGYLFEDEEIRLNKVKRNEKLLFQELKENDNSPYTNYQLGKNFIILGKYQEAL
                     YYLEKSYELYSKLELAPGYLITSLVKTYLYLGKHKKCERLCLKYIKKDMNNIDIYYYI
                     AQAQVDLGKYENSIDSYKRYIYLLDNYEISTQANSLFSDTDTVGLRDEAIITLIKIYY
                     KLEKYEFVISEYNNIEDVEKKKNVYFSLFMSLYKLNRFEDIKNYYKEVSNSKIEKNSF
                     YRNIEEVINNIKEDEKEYVYKILCDIEGNYGILNQ"
     gene            complement(1375..2247)
                     /locus_tag="OE968_002133"
     CDS             complement(1375..2247)
                     /locus_tag="OE968_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellin"
                     /protein_id="HCP7219412.1"
                     /translation="MRVNTNVSALIANNQMGRNVNAQSKSMEKLSSGVRIKRAADDAA
                     GLAISEKMRAQIKGLDQAGRNVQDGISVVQTAEGALEETGNILQRMRTLSVQSSNETN
                     TAEERQKIADELLQLKDEVERISSSIEFNGKKLLDGSSTEIRLQVGANFGTNVAGTSN
                     NNNEIKVALVNTSSIMSKAGITSSTIASLNADGTSGTNAAKQMVSSLDVALKELNTSR
                     AKLGAQQNRLESTQNNLNNTIENVTAAESRIRDTDVASEMVNLSKMNILVQASQSMLA
                     QANQQPQGVLQLLG"
     gene            complement(2349..2684)
                     /gene="fliT"
                     /locus_tag="OE968_002134"
     CDS             complement(2349..2684)
                     /gene="fliT"
                     /locus_tag="OE968_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein FliT"
                     /protein_id="HCP7219413.1"
                     /translation="MDKLKEKLNLYKDISLQIINLIEKEEYIKISIKLGERQEIINSV
                     SEIDRNDFIQLYNRMELIEIDSRIRDILQGQLLEVKKELHEYKLTKQVNTMYYNLNRE
                     KVNIFNKKV"
     gene            complement(2687..4210)
                     /gene="fliD"
                     /locus_tag="OE968_002135"
     CDS             complement(2687..4210)
                     /gene="fliD"
                     /locus_tag="OE968_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar filament capping protein FliD"
                     /protein_id="HCP7219414.1"
                     /translation="MSSISPIRVTGLSGNFDMEGIIEASMIRDKEKVDKAKQEQQIVK
                     WKQEIYRNVIQESKDLYDKYLSVNSPNSIVSEKAYSSTRITSSDESIIVAKGSAGAEK
                     INYQFAVSQMAEPAKFTIKLNSSEPIVQQFPPNASGASSLTIGDVNIPISEQDTTSTI
                     VSKINSLCADNDIKASYSEMTGELIISRKQTGSSSDINLRVIGNDNLAQQIANDNGIT
                     FINDAGGNKVANVYGKNLEADVTDEHGRVTHISKEQNSFNIDNIDYNVNSKGTAKLTS
                     VTDTEEAVKNMQAFVDDYNKLMDKVYGLVTTKKPKDYPPLTDAQKEDMTTEEIEKWEK
                     KAKEGILRNDDELRGFVEDIQSAFFGDGKNIIALRKLGINESENYNKKGQISFNADTF
                     SKALIDDSDKVYKTLAGYSSNYDDKGMFEKLKDIVYEYSGSSTSKLPKKAGIEKTASA
                     SENVYSKQIAEQERNISRLVEKMNDKEKRLYAKYSALESLLNQYSSQMNYFSQAQGN"
     gene            complement(4231..4587)
                     /gene="fliS"
                     /locus_tag="OE968_002136"
     CDS             complement(4231..4587)
                     /gene="fliS"
                     /locus_tag="OE968_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar export chaperone FliS"
                     /protein_id="HCP7219415.1"
                     /translation="MELNLAELDKLSKEELLLMLVDGTVKYTNISKEALLNNDYLKAH
                     NELVRVQNIFTELMTTLDQDAGQWAKDMYKVYEFIKSELAIADENKDIKIIDDILPIV
                     KQIRDTWHEVYNQLKI"
     gene            complement(4587..4982)
                     /gene="fliS"
                     /locus_tag="OE968_002137"
     CDS             complement(4587..4982)
                     /gene="fliS"
                     /locus_tag="OE968_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar export chaperone FliS"
                     /protein_id="HCP7219416.1"
                     /translation="MYGENPYNSYKQNAVFMASKEQLLLMLVDGAVKYTKIAKTAILD
                     KNTQKAHRELIRVQDIFTELMVTLDQNAGQWAKDMYRVYDFVRYELSRANIRKDIQII
                     DNVLPVIEQIKDTWHEADKKSKEERSRYK"
     gene            complement(5004..5216)
                     /gene="csrA"
                     /locus_tag="OE968_002138"
     CDS             complement(5004..5216)
                     /gene="csrA"
                     /locus_tag="OE968_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011987028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon storage regulator CsrA"
                     /protein_id="HCP7219417.1"
                     /translation="MLVISRKKDEAVLIGESIEVKIVGVDGNNVKLAISAPNNISILR
                     KEIYEKVKSENIKATNKNIKILKSLK"
     gene            complement(5210..5602)
                     /locus_tag="OE968_002139"
     CDS             complement(5210..5602)
                     /locus_tag="OE968_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar assembly protein FliW"
                     /protein_id="HCP7219418.1"
                     /translation="MMKVTLKKGILGFENLKEYELLDIEDNDYLKEFNSTEEEGIGFV
                     VVSPFEIINEYEIVLNQETIEKLEVKSPKDVVLFNIITLGQTFEESTVNMKAPIVINI
                     KTNFGMQIILQDDKYSIRHPLLRGDSGC"
     gene            complement(5618..6550)
                     /gene="flgL"
                     /locus_tag="OE968_002140"
     CDS             complement(5618..6550)
                     /gene="flgL"
                     /locus_tag="OE968_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-associated protein FlgL"
                     /protein_id="HCP7219419.1"
                     /translation="MRVSTGMMSSSYLNSLQDNLQRLDKVNRQVNTTKEINKLSDNPY
                     KAIKILNSKSEIKTMETYVENCKDTGNWLETTDTALDQLGKLLSDIKKTLVASGDGAY
                     SDDELKTLSNETNEKMKEIANALNATHEGKYIFSGSNTGVPPVECIDNADGSVSLKFN
                     SSLNLNKLNDSLSMDIAQGISVDYNVKLSSLGFDPTKTDPFEELNNISKKLANPDADA
                     IKELTTTCLGDMEQLIENTVNVRSIYGTKANTVEAMKEKNDDSLIQLKDILSQNEEID
                     YGEKLVQLKAAELTYQASLQTGGKLFNVSILDYI"
     gene            complement(6569..7879)
                     /gene="flgK"
                     /locus_tag="OE968_002141"
     CDS             complement(6569..7879)
                     /gene="flgK"
                     /locus_tag="OE968_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-associated protein FlgK"
                     /protein_id="HCP7219420.1"
                     /translation="MAGLFSILNTANSGMNAHQKAIQTISHNISNLDTDGYSRQRTEF
                     ATNSPMYMPSLSNSIARGQLGTGVHVTDVTRARNSFYDYQFRAEAHKYGKTVSKYDYY
                     NTIETILNEPSDYGISAGIDDFFKGWESLSKDINSDSKKSLVVENASNLATLISESYK
                     KLDKLKEDIDSNIDTEIKQINDMLKSLEDLNKSIDIISGSGSTPNDLLDERDRILDNL
                     SFKLDFENSDVKNMLADGKLELNELKNPDGTWKTGISGTLQGLFEMHGKIDTYKSDLK
                     DVSDGLAKQINDVYNTSAGITVTDFFITSNVDGEDIIKINPAIKSNPNELKLTADEAS
                     KIAKLKDEKIDIGVAGGKVSTISDHYKAFAESIGLDSQKVNQDEANQRKIINNIDNSR
                     MSVSGVSLDEEMTELIKIQRSYQASAKVMSTAVQLLDVVINGII"
     gene            complement(7897..8313)
                     /locus_tag="OE968_002142"
     CDS             complement(7897..8313)
                     /locus_tag="OE968_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein FlgN"
                     /protein_id="HCP7219421.1"
                     /translation="MITDLKVIIYEEKNIISKMMELLKEQFDYIVEKDLENLNMLNPK
                     LEDISRELASIEIKRRQLFGDDISMSEVVENSNDGYLKEIYTDLKHILALAKNQQESN
                     DSLIKKELIFTKKMINFIKPADKQTTTYNSYGNIRK"
     gene            complement(8318..8593)
                     /gene="flgM"
                     /locus_tag="OE968_002143"
     CDS             complement(8318..8593)
                     /gene="flgM"
                     /locus_tag="OE968_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis anti-sigma factor FlgM"
                     /protein_id="HCP7219422.1"
                     /translation="MDIKNVSSNIVVNNYLKNTSGIKKVEEVKKINKTDKIELSKFAK
                     EMASVSNMSDENIRNKKVDEIKNALENGTYKIKPKEIAKKMIEDMRG"
     gene            complement(8745..9059)
                     /locus_tag="OE968_002144"
     CDS             complement(8745..9059)
                     /locus_tag="OE968_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliM/FliN family flagellar motor switch protein"
                     /protein_id="HCP7219423.1"
                     /translation="MNSKKEDIYELNFGQLIEEKSGVIEENQNVFNAKVNVAVSIGNT
                     TETIKNILDLKEGSIIKLSKNVDEKLDIYANDRLFAYGESIITNERLSVRLSKIEDPD
                     VN"
     gene            complement(9083..9511)
                     /locus_tag="OE968_002145"
     CDS             complement(9083..9511)
                     /locus_tag="OE968_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaaR family protein"
                     /protein_id="HCP7219424.1"
                     /translation="MGINIDKLNISPSINMEVKKLKESNKFSDKLNSLKQSSSLEDIK
                     RNLESVKKAGERLVLTQNYGDISIYKNAVKEYLKSVVDNMYSLDKNSSFWEHQYYKNV
                     KIVDSKLEDMTSKLISEEKENIDIVSTVDMIQGLLIDMYR"
     gene            complement(9520..10188)
                     /locus_tag="OE968_002146"
     CDS             complement(9520..10188)
                     /locus_tag="OE968_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing
                     protein"
                     /protein_id="HCP7219425.1"
                     /translation="MNEISSLINILALTQLSGSNTTNQCNCTYNNSSGFDMIMMTLLK
                     ALSQNNQHTSNSYNLLSNSENLFNELDNVVNNTTSRFIDVDTKDKNVKLRIENAVDQA
                     SKKYNVDSNLIKAIIKVESDFNPNTVSSAGAKGLMQLMPENCRDLGVTDPFNIEQNID
                     AGTRHIKEYIDMFGGSIEMGLMAYNGGPGRMKSRGVESISDLYKMPKETQNYIPKVMK
                     YYRG"
     gene            complement(10218..11201)
                     /gene="rfbB"
                     /locus_tag="OE968_002147"
     CDS             complement(10218..11201)
                     /gene="rfbB"
                     /locus_tag="OE968_002147"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HCP7219426.1"
                     /translation="MKKILITGGAGFIGSNFIHYMLNKYVDYFIVNLDLLTYAGNLET
                     LIEIQDNSNYKFVKGDISNREQVYKLFEEERFDIVVNFAAESHVDRSVENPDLFIKTN
                     IIGTQVLLDASIKYGVKRYHQISTDEVYGDLPIDRKDLFFTEQSSINPSSPYSASKAS
                     ADLLVSSYYRTYGLLTTISRCSNNYGPYHFPEKLIPLMILNALENKQLPVYGNGENVR
                     DWLHVYDHCTAIDLIIHKGNIGEIYNIGGHNERSNLEVVKMILNLLGKSEELISYVND
                     RPGHDLRYAIDATKIENELGWKAKYDFDLGIKETVKWYIENESWWKAVLSV"
     gene            complement(11239..11796)
                     /gene="rfbC"
                     /locus_tag="OE968_002148"
     CDS             complement(11239..11796)
                     /gene="rfbC"
                     /locus_tag="OE968_002148"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HCP7219427.1"
                     /translation="MGKINVIKTKIEGLYIVEPNVFYDERGYFMESYNKKDFIEQGLD
                     MCFIQDNESSSRKGVLRGMHFQVKYPQGKLVRVTEGEVFDVAVDLRKDSQTFGKWEGV
                     ILSDKNKKQFYIPEGFAHGFLVLSEKAVFSYKCTNYYYPEFENGFIWNDKQISIEWPL
                     KGIEEIFLSEKDKKQKSFKDICTRR"
     gene            complement(11845..12714)
                     /gene="rfbA"
                     /locus_tag="OE968_002149"
     CDS             complement(11845..12714)
                     /gene="rfbA"
                     /locus_tag="OE968_002149"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HCP7219428.1"
                     /translation="MKGIILAGGSGTRLYPITKCISKQTLPIYDKPMIYYPMSVLMLA
                     GIQDILIISTPRDIKAFEELFGDGSSLGLNITYAIQEKANGIAEAFIIGEEFIGNDRV
                     SLVLGDNIFYGYGFSERLENAVKRKGATIFGYHVSNPNSFGVVEFDKDFNVLSIEEKP
                     TVPKSNYAIPGLYFYDNDVVEIAKLVEPSDRGELEITSINSEYLKRGKLKVELLGRGM
                     AWLDTGTHKGLLDASNYVEVVQTRQGLYIACLEEIAYTKGYISREQLMKLAKPLIKTE
                     YGQYLLKLASEDM"
     gene            complement(12823..13695)
                     /gene="rfbD"
                     /locus_tag="OE968_002150"
     CDS             complement(12823..13695)
                     /gene="rfbD"
                     /locus_tag="OE968_002150"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HCP7219429.1"
                     /translation="MKILITGSNGQLGKELVNQLEAINQSINQPKYVILATTRSDLDI
                     SNQTNVDNFILHNKPDVVVNCAAYTKVDACEDNIEIAYKINALGVRNLAIASEKVNAK
                     LIHISTDYVFNGFSKYPYREDNKTEPNSVYGKSKLMGEKFVEQFSHKYFILRTAWLYG
                     NGNNFVKTMIKLSLENKEVNVVNDQFGTPTSTVDLAKIIIRIMETEHYGVYHATCEGE
                     CSWYDFAKKIFKLKNIDIKVNPIKSNEFKCKAPRPLYSVLDNFMLKLIGLNSFRKWEE
                     SIEEYLERYDINEK"
     gene            complement(13901..18982)
                     /locus_tag="OE968_002151"
                     /pseudo
     CDS             complement(13901..18982)
                     /locus_tag="OE968_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013725947.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
     gene            complement(18993..20525)
                     /gene="purH"
                     /locus_tag="OE968_002152"
     CDS             complement(18993..20525)
                     /gene="purH"
                     /locus_tag="OE968_002152"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HCP7219430.1"
                     /translation="MSKRALISVTDKTGVVEFAKELNKLDYEIISTGNTFKTLKENGV
                     NVMQVEDVTNFPEILDGRVKTLNPYIHGGILYKRDKESHVETVNEHKIHSIDLVAVNL
                     YDFEGTLKAGKSHDEIIENIDIGGPSMIRSAAKNYKDVIVVVDIKDYDSIIEKLKTDT
                     MTLEDRKKLSYKAFSTTGRYDALISSYFAGEVGDTYPDILNLTFQKEQTLRYGENPHQ
                     NGFLYSQSNAKNPILNYEQLGGKELSFNNLNDLHGCLEVMREFKDSEEVVSVAIKHAN
                     SCGVGLGKDAFEAYTKCYEADKVSIFGGIVGITSTIDKATAEKLNEIFLEIVVAYDFE
                     PEALEILKQKKNLRILKLAKIENSLQPYEMKYLDGKLLIQDRNNILAEKSENVTKEKP
                     TDAQLKDMEFGMRVVKNMKSNAIAVVKNGQTLALGCGQTSRIWALKNALENNKDKDFT
                     GAVLASDAFFPFDDCVTLAHEYGISAVVQPGGSIKDKDSIEACDKYDMVMVFTGIRHF
                     KH"
     gene            complement(20518..21111)
                     /locus_tag="OE968_002153"
     CDS             complement(20518..21111)
                     /locus_tag="OE968_002153"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HCP7219431.1"
                     /translation="MLNIGVLISGGGTNLQAVIDGTESGEIKGQVKVVISSKQGAYGL
                     ERAKNHNIKAICETDEDKIIEILKENKIDLVVLAGYLKIISPKLVNEFRNKMINIHPS
                     LIPSFCGAGFYGEKVHQGVIDYGAKVTGATVHFVDEGADTGPIIMQDVVKVNQDDDAK
                     TLAKRVLEVEHRILKESISLFCENKLKLQGRRVFINE"
     gene            complement(21105..22181)
                     /locus_tag="OE968_002154"
     CDS             complement(21105..22181)
                     /locus_tag="OE968_002154"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HCP7219432.1"
                     /translation="MLTYKESGVDIDEGNRAVDLIKGKIKGTYDGNVVGDLGNFSGLY
                     SLKDFVGMKEPVLLASTDGVGTKLKIAQMMDKHDTVGIDLVAMCVNDLICQGAKPLFF
                     LDYIALGKLVPEHIEKIVGGIADGCKMSGCALIGGETAEMPGMYGEDDYDLAGFSVGI
                     ADKEKIVSGNNVKSGDVLVGISSSGVHSNGFSFIRKIFLETYNYKMEQYVEELGMTVG
                     EALLTPTKIYVKLALDVLAKHDIKAIAHITGGGLIENITRVIPKGLGLDINKKSWEKP
                     PIFKMIEGFNAVDERELHKSFNMGIGLVLIVDKENADDVVNFINNRENDNAAYVDKKY
                     SELLEDKAYIIGEVVDSHEGVELC"
     gene            complement(22175..23542)
                     /gene="purF"
                     /locus_tag="OE968_002155"
     CDS             complement(22175..23542)
                     /gene="purF"
                     /locus_tag="OE968_002155"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HCP7219433.1"
                     /translation="MCGVLGIYSNKDVTKELYYSLYSMQHRGQESCGLALLDDGEIKY
                     KKDMGLVGDVFKENELSKLKGNIGIGHVRYSTAGGSHVSNCQPLVGSCRKRQLAIAHN
                     GNLVNANYLKDMLEEDGYMFQTNSDTEVILYILARYYKGDIVESLKVTMDYIKGAYAL
                     VIMSQEELVAVRDPHGFRPLVLGKKGDEYIFASENCAIDILGGEVIRDVEPGEIIVVK
                     DGELKSYFYSENYKPVKKSCIFEHIYFARNDATIDNVNAYEFRIKCGERLAQNETVKA
                     DMVVPVPDSGWPGAIGYANASGLKISEGLVKNRYVGRTFIKPTQEEREIAVKIKLNPL
                     STIIKGKSIILVDDSIVRGTTSKQLVKSLREAGAKEIHLRITSPPVAYSCYYGIDTPN
                     RSKLIASSNNVEEMREYIGCDSLKFLDIEGMLDATEHKSTFCKACFDGEYPVKKIDKE
                     ELLSC"
     gene            complement(23554..24252)
                     /locus_tag="OE968_002156"
     CDS             complement(23554..24252)
                     /locus_tag="OE968_002156"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HCP7219434.1"
                     /translation="MLLYEGKAKQVYSTDNENEYVVYYKDDATAFNGEKKAEISSKGI
                     LNNKISTIIFEMLKENNINTHFIKSLSDREMLVKKVEILPLEVIVRNIAAGSICKRVG
                     LEEGVVFDEPIFEISYKNDAYGDPMLNDDYAVAMKLATREELKFLREETLKINELLKA
                     FFLKLNLKLVDFKIEFGKDSEGNIILADEVSPDTCRLWDVNTNEKLDKDRFRKDLGDL
                     VEGYTEVLSRMNNK"
     gene            complement(24258..24734)
                     /gene="purE"
                     /locus_tag="OE968_002157"
     CDS             complement(24258..24734)
                     /gene="purE"
                     /locus_tag="OE968_002157"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HCP7219435.1"
                     /translation="MKVAVVMGSKSDYPKLEEGIKLLEKYGIEVVARALSAHRTPEQL
                     SIFLKEIEDDTDVIIAAAGKAAHLPGVIASQTLIPVIGLPIKSSTMDGLDSLLSIVQM
                     PKGIPVATVTIDLGLNAALLALQIMTLKYPKLKEDLKSYREEMAQKVLEDDKNLRG"
BASE COUNT         7363 a         4709 c         2624 g        10365 t
ORIGIN      
        1 tttgatttaa aatgccataa ttaccttcaa tgtcacaaag gattttatat acatactctt
       61 tttcatcctc tttaatatta tttataactt cttctatatt tctataaaaa ctattttttt
      121 caattttaga atttgaaact tctttataat aattttttat atcttcaaat ctattcaatt
      181 tatatagtga cataaataag ctaaagtaca cattcttttt cttttccaca tcttcaatgt
      241 tattatactc tgaaattaca aactcatatt tttcaagctt ataataaatc tttatcagtg
      301 taataatagc ctcatctcta agccctacag tatcagtgtc tgaaaataaa ctatttgctt
      361 gtgtacttat ttcataatta tctaacaagt aaatatatct cttatacgaa tctatactat
      421 tttcatactt tcctaaatct acttgtgctt gtgcaatata ataatatata tcaatattat
      481 tcatgtcttt cttaatatac tttaagcaca atctttcaca cttcttatgt tttcctaaat
      541 ataaatatgt ttttacaagg cttgttatca agtaaccagg tgccaattct agtttagaat
      601 ataattcata agatttctca agatagtata aagcctcctg atattttcct aatataataa
      661 aatttttccc taattgatag tttgtatatg gagaattatc attctctttt aactcttgaa
      721 ataatagttt ttcatttctt ttcaccttat ttaatcttat ttcttcatct tcaaacaaat
      781 atccataatg ttcaaaatca gcaacattat taaatatagg gtttttgtat attggttgtt
      841 catgtacttt accatggtat ctaaaatcaa cgtttttaaa aagtctaagc actgaacaat
      901 atccatataa ttttttatca tatgagtaaa gattttttaa ttgtattgaa gcagaattaa
      961 attttttatc aagaccatct ttaaaaaatt ttacaatagt tgaagaatca attagtattt
     1021 catctgcatc taatataagt aaccattcac ctttagcata ggatattgat atatttctca
     1081 tactagaaaa atcattattc caattatgaa aatacacttt ttccgtgtac ttcttagata
     1141 tttttatagt atcatctgta gaacctgtat cgactattat aagttcactt tctatagaat
     1201 ttcttaatgt ggttaatgat tttaaagttt tttcaagtat tttttcttca tttttaacaa
     1261 tcataactat actaagtaac atataaattt tcctttcaaa agtatatttg taaaaaaaga
     1321 aaggagtaaa gcaaagcctt accctttctt ctatatccaa tatacaaaat tattttatcc
     1381 taataattgt aaaactcctt gtggttgttg attagcttga gcaagcattg actgtgatgc
     1441 ttgaactaat atattcattt tagataagtt aaccatttct gaagcaacat ctgtatctct
     1501 tattcttgat tcagctgctg taacattttc tatagtatta tttaagttgt tttgagttga
     1561 ttctagtcta ttttgttgtg cccctaattt tgctcttgat gtatttaatt ctttaagagc
     1621 tacatctaag ctagatacca tttgtttagc tgcatttgtt ccagaagttc catctgcatt
     1681 taagcttgct attgtagaac ttgttatacc tgctttactc attatacttg aagtatttac
     1741 tagagcaact tttatttcat tgttgttgtt agatgttcct gcaacatttg ttccaaagtt
     1801 tgctccaact tgtaatctta tttctgtaga acttccatca agtaatttct taccattaaa
     1861 ctcaattgag cttgatattc tttcaacttc atcttttaat tgtagtaact catcagctat
     1921 cttttgtctt tcttcagcag tattagtttc atttgaagat tgtactgata aagttctcat
     1981 tctttgtagt atgttaccag tttcttctaa tgcaccttct gctgtttgta caacagatat
     2041 accatcttga acgtttcttc ctgcttggtc taaacctttt atttgagctc tcattttctc
     2101 agatatagca agcccagcag catcgtcagc agctctctta attctaacac cagaagatag
     2161 cttctccata gacttacttt gtgcatttac gtttcttccc atttggttat ttgctatcaa
     2221 agcacttaca tttgtattaa ctctcattat tttaccctcc ttagtatagt tgacatcctt
     2281 gtcatttcta cttttaatct tttttattaa ttcttcattt atataatcgg acaagatggt
     2341 acataacttt atactttttt attaaaaata tttacttttt ctctatttaa gttataatac
     2401 attgtgttca cttgtttagt aagcttatac tcatgtaatt ctttttttac ttctaataat
     2461 tgtccttgta aaatatctct tatcctgcta tcaatttcaa ttaattccat tctattataa
     2521 agctgtataa aatcatttct atcaatttca cttacactat ttataatctc ttgtctttca
     2581 cctaacttaa tacttatctt tatatattct tccttttcaa tcaaatttat aatttgtaaa
     2641 gatatatctt tatataaatt taatttttct tttaatttat ccataattaa ttaccctgtg
     2701 cttgtgagaa ataattcatt tgggaagaat actgattcaa caaagattct aaggctgaat
     2761 atttagcata aagtcttttc tctttatcat tcattttttc aactaacctg cttatatttc
     2821 tttcttgctc tgcaatttgt tttgaatata cattttcact agcagaagca gttttttcta
     2881 tacctgcttt tttaggaagt ttagaagttg aacttccaga atattcatat acaatatctt
     2941 ttagcttttc aaacattccc ttatcatcat aattcgaaga ataacctgct agtgttttgt
     3001 ataccttatc actatcatct ataagagcct ttgaaaaagt atctgcatta aatgatattt
     3061 gacctttttt attgtaattt tcactttcat tgatacctag ttttcttaat gcaataatat
     3121 tttttccatc tccaaaaaat gcagattgaa tatcttcaac aaaacctctt aactcatcat
     3181 catttctaag tataccttct ttagctttct tttcccattt ttctatttct tcagttgtca
     3241 tatcttcttt ttgggcatct gtaagaggcg gataatcttt tggtttttta gtagtaacta
     3301 aaccatagac cttgtccatc agtttattat aatcatccac aaatgcttgc atatttttaa
     3361 cagcttcttc agtatcagtg acagaagtca actttgcagt tccttttgaa tttacattat
     3421 agtcaatatt atctatatta aatgaatttt gttctttact tatatgagtt actcttccat
     3481 gttcatcagt tacatcagct tctagattct ttccatatac atttgccact ttgtttccac
     3541 cagcatcatt tataaatgtg ataccattat cattagcaat ttgctgagct aaattgtcat
     3601 ttccaattac tcttaaatta atgtctgatg acgaaccagt ctgttttctt gaaataatca
     3661 attcacctgt catctcacta taagaagcct ttatatcatt atctgcgcaa agggagttta
     3721 tcttacttac aatagtactt gtagtatctt gttcagatat tggtatattt acatctccta
     3781 tagttaaaga actcgctcca ctagcatttg gaggaaactg ttgaacaata ggttcacttg
     3841 aatttaattt aatagtaaat tttgctggtt cagccatttg agaaactgca aattgataat
     3901 ttattttttc tgcaccagct gagccttttg ctactataat actttcatca gaactggtta
     3961 ttcttgtaga agagtatgct ttttcactta ctatactatt aggagaattt acgcttagat
     4021 atttatcata aagatctttt gattcttgta taacatttct atatatttct tgcttccatt
     4081 taacgatttg ttgttcttgt tttgctttat caactttttc cttgtctcta atcatactag
     4141 cttcgattat gccttccata tcaaaatttc ctgaaagacc tgtaactctt ataggactta
     4201 tacttgacat acctttatcc ctccatccaa ttatattttt agttgattgt aaacttcatg
     4261 ccatgtatct ctaatttgtt ttactattgg caatatatca tcaattattt taatatcttt
     4321 attttcatca gctattgcta attcagattt tataaattca taaactttat acatatcctt
     4381 tgcccattga cctgcatctt ggtctaatgt agtcattagt tctgtaaata tattttgaac
     4441 tcttacaagt tcattatgtg ctttcaaata gtcgttattt aaaagagctt ctttggatat
     4501 attggtatat tttactgttc catctacaag catcaatagt aattcctctt ttgataactt
     4561 atctaattca gctaaattta attccattat ttgtacctac ttctttcttc tttacttttt
     4621 ttatcagctt catgccaagt atctttaatt tgttctatta caggcaacac attatctatt
     4681 atttgaatgt cttttctaat attagctctt gaaagttcat atcttacaaa atcataaact
     4741 ctgtacatat cctttgccca ttgacctgca ttttggtcta atgtaaccat tagttctgta
     4801 aatatatcct gaactcttat aagctctcta tgcgcttttt gtgtattttt atctaagata
     4861 gctgttttgg ctattttggt atattttact gctccatcaa caagcataag taacaattgt
     4921 tcctttgatg ccataaaaac agcattttgt ttataagaat tataaggatt ttctccatac
     4981 atatattact tcctccaagc ttattatttt aatgacttta aaatttttat atttttattt
     5041 gtagctttta tattctcact ctttactttt tcgtatattt cttttcttaa tatacttata
     5101 ttgttaggcg ctgatatagc tagtttcaca ttgtttccat ctacccctac aatttttact
     5161 tctatgcttt ctcctataag tactgcttca tctttttttc ttgaaattac tagcatccac
     5221 tatcacctct caataatgga tgccttattg aatatttatc atcctgtaaa attatttgca
     5281 ttccaaaatt agtttttata tttatcacta taggagcttt catgttcaca gttgattctt
     5341 caaatgtctg accaagagta attatattaa ataatacaac atcctttgga gatttcactt
     5401 ctagtttttc tattgtttcc tgatttaaaa ctatttcata ttcattgata atctcaaatg
     5461 gagatacaac aacaaatcct ataccttctt cttcagtaga attaaattct tttaaataat
     5521 cattatcttc tatatctaaa agctcatatt cttttaaatt ttcaaaacct aatatacctt
     5581 tttttaatgt aaccttcatc atatctgcgt tattttatta tatgtaatct aatatagata
     5641 cattaaataa ctttcctcct gtttgtagtg aagcttgata agttaactct gctgccttta
     5701 attgaacaag tttttcacca taatctattt cttcattttg tgacaaaata tcctttaact
     5761 gtatcaaact atcatcgttt ttttccttca tagcctctac tgtatttgct tttgtcccat
     5821 atatagacct aacatttact gtattttcta ttagttgttc catatcgccc aaacaagttg
     5881 ttgtaagctc ttttatagca tcagcatctg gatttgctaa tttttttgat atgttattta
     5941 actcttcaaa tgggtcagtt tttgttgggt caaatccaag gctactcaat ttaacgttat
     6001 aatctacact tattccttga gctatatcca tactcaaaga gtcatttaat ttattaagat
     6061 ttagactaga attaaacttt aaactcactg aaccatcagc attatctata cattcaacag
     6121 gtggtacccc cgtatttgaa cctgaaaata tgtacttccc ttcatgtgtt gcatttaaag
     6181 catttgcaat ttctttcatt ttttcattag tttcattact aagagtcttt aattcatcat
     6241 ctgagtatgc accatcacca cttgccacca aagttttctt tatgtctgat aataattttc
     6301 caagctgatc taatgcagta tcagtagttt ctaaccaatt ccctgtatct ttacaattct
     6361 caacataagt ctccatagtc tttatttcac tttttgagtt taatatcttt attgctttat
     6421 atggattatc tgatagcttg tttatttctt ttgttgtatt aacttgtcta ttaaccttat
     6481 ccaatctttg tagattatct tgtagtgagt ttagatagct gctagacatc atacctgtac
     6541 tgactctcat tataaattcc cccttctatt aaattattcc atttattaca acatccagta
     6601 gttgcacagc tgttgacata acttttgcac tagcttgata tgaacgttgt atttttataa
     6661 gctctgtcat ttcttcatcc aaagatacac ctgaaacact cattcttgag ttatcaatat
     6721 tatttataat tttacgttga tttgcttcat cttgatttac tttttgagaa tctaaaccga
     6781 ttgattctgc aaaggcttta tagtggtcac ttattgtact tacttttcca ccagccaccc
     6841 caatatctat tttttcatcc tttaacttag caatttttga agcttcatca gcagtaagct
     6901 ttaattcatt tgggttactc tttatagctg gatttatctt tataatatct tcaccatcta
     6961 catttgaagt tataaaaaaa tctgttactg ttattcctgc agacgtatta taaacatcat
     7021 ttatctgttt agctaatcca tcagatacat cttttaaatc gcttttatat gtatcaatct
     7081 taccatgcat ttcaaacaag ccttgtaagg tccctgatat acctgttttc caagttccat
     7141 ctggattttt taattcatta agttctaatt taccatctgc aagcatattt ttaacatcac
     7201 tattttcaaa gtctagttta aaactcaagt tatctaaaat tctatctctt tcatcaagta
     7261 aatcatttgg tgtagagcca gaaccagata taatatcaat agatttattt aaatcttcaa
     7321 gactttttaa catgtcattt atttgtttta tctcagtgtc tatattagaa tctatatctt
     7381 cttttaactt atcaagcttc ttataacttt cacttattaa agttgctaaa ttagatgcgt
     7441 tttctaccac tagacttttt ttactgtcac tatttatatc ctttgataat gactcccatc
     7501 ctttaaaaaa atcatctata cctgcagata ttccatagtc tgatggttca tttagtatag
     7561 tttctatagt attgtaataa tcatattttg aaactgtctt accatactta tgagcttctg
     7621 ccctaaattg gtaatcataa aaactatttc tagctcttgt tacatccgtt acatgtactc
     7681 cagtccctaa ttgtcctctt gcaattgaat tactcaaact aggcatatac attggactat
     7741 ttgtggcaaa ctcggtcctt tgcctagaat aaccgtctgt atctagatta cttatattat
     7801 gagaaattgt ctgtattgct ttttggtgcg cattcattcc tgaattagct gtatttaaaa
     7861 tggaaaataa tcctgccata tttctcctcc taatatttat tttctaatat ttccataaga
     7921 attataagtt gtagtttgct tatcagctgg ttttatgaaa ttaatcattt ttttcgtaaa
     7981 aataagttct ttctttatta gagaatcatt tgattcttgt tgatttttag ctaaagcaag
     8041 aatgtgtttc aagtctgtat atatttcttt taagtatcca tcattactat tttcaacaac
     8101 ttcactcatt gaaatatcat caccaaaaag ttgtcttctc tttatttcta tggatgcaag
     8161 ctccctgcta atatcttcta gtttaggatt taacatattt aaattttcta agtctttttc
     8221 aactatataa tcaaattgtt cttttaataa ttccatcatc ttactaatta tatttttttc
     8281 ttcatatatt ataactttta agtctgtaat catgacttta tcctcgcata tcctctatca
     8341 tttttttcgc aatttctttt ggttttattt tgtaagttcc attttctaat gcatttttta
     8401 tttcatcgac ttttttattt ctaatattct catcactcat atttgacaca cttgccattt
     8461 cctttgcaaa tttagataac tctatcttat ctgttttatt aattttttta acctcttcca
     8521 ctttttttat accagatgta ttctttaaat aattattcac tacaatattt gaacttacat
     8581 ttttaatatc catagtttca cctccaaaat tacatactta taatttagtt atcgctcata
     8641 aaataaaaat atttatataa ttcacacata ttttaaattt tttataaaaa tatcccctta
     8701 gctaaactca tacagaatag cctaaaggga tactatttaa aatgctaatt tacatctgga
     8761 tcttctattt tagataatct tacagataac ctctcatttg taataatgct ttctccataa
     8821 gcaaacaatc tatcgtttgc atatatatct aatttttcat ccacattctt acttaatttt
     8881 attatagagc cttcttttaa atctaatata ttttttattg tttctgttgt atttcctata
     8941 gaaacagcta catttacttt tgcattaaaa acattttgat tttcttctat aacaccagat
     9001 ttttcttcta ttaattgccc aaaattcaat tcatatatat cctctttttt gctattcata
     9061 aaatttttct ccttgtataa ccttatctat acatatctat caataagcct tgtatcatgt
     9121 caacagtaga aacaatatct atgttttctt tttcttcact aattaactta ctagtcatat
     9181 cctcaagttt actatcaaca atctttacat tcttataata ctgatgctcc caaaagctac
     9241 tatttttatc aagtgaatac atattatcta caacagattt taggtattct tttactgcat
     9301 ttttatatat actaatatcg ccatagtttt gagtaagtac aagcctttct cctgcctttt
     9361 ttacactttc caaatttcgt tttatatctt ccaatgaaga agattgtttt aaagagttta
     9421 atttgtcaga aaatttatta ctctctttta gttttttaac ctccatattt atacttggac
     9481 ttatgtttag cttatctata tttattccca taataaagcc taccctctat aatatttcat
     9541 aaccttagga atataatttt gtgtttcttt tggcatttta tacaggtcag agattgattc
     9601 tactcctcta cttttcattc ttccaggacc accattatat gccatcaatc ccatttctat
     9661 gctccctcca aacatatcaa tgtattcctt aatatgtcta gttccagcat ctatattctg
     9721 ttctatatta aaagggtctg taactcctaa gtctctgcag ttttctggca taagttgcat
     9781 aagaccctta gcaccagcag aagaaacggt atttggatta aaatctgatt caactttaat
     9841 tattgctttt ataagatttg aatctacgtt atattttttt gatgcttgat ctacagcatt
     9901 ttcaattctc aactttacat ttttatcttt tgtatcaaca tctataaatc tactagtggt
     9961 attatttact acattatcaa gttcattaaa taaattctca gaattagaca ataaattgta
    10021 gctattagaa gtatgttgat tattttgtga taatgctttt aacaaggtca tcataatcat
    10081 atcaaatcca gatgaattat tatatgtaca attacattga tttgtagtat tactaccaga
    10141 taattgagtc aatgctaata tattaattag tgaacttatc tcattcaata taaaacgccc
    10201 ctttctaaat tttaaagtta tactgataaa acagctttcc accaagattc attttctata
    10261 taccacttaa cagtttcttt tatacccaaa tcaaagtcat attttgcctt ccaacctaac
    10321 tcattctcta ttttagttgc atcaatagca tatcttaaat catgaccagg tctatcattt
    10381 acataggata ttaactcttc agatttacct aaaagattta atatcatttt tactacttct
    10441 agattacttc tttcattatg acctcctata ttgtaaatct cccctatatt tcctttatgt
    10501 attattaagt ctatagcagt acaatggtca tatacatgta accaatctct tacattttcc
    10561 ccattcccat atactggcaa ttgtttgttt tccaaagcat ttaaaatcat aagaggaatc
    10621 aatttttcag gaaaatgata tggcccataa ttgttggaac acctagatat agttgttaac
    10681 aatccatatg ttctataata agaacttacc aataaatctg ctgatgcttt agaagctgaa
    10741 tatggagaac ttggattgat agaagattgt tctgtaaaga ataaatcctt tctatcaatt
    10801 ggtaaatcac catacacttc gtctgtagat atttgatgat accttttaac tccatatttt
    10861 atagatgcat ctaaaagtac ttgtgttcct ataatgtttg ttttaataaa taaatcagga
    10921 ttctcaactg acctatctac atgagattca gcggcaaagt taacaactat atcaaacctt
    10981 tcttcttcaa atagcttata cacctgctcc ctatttgaaa tatctccttt aacaaattta
    11041 taattggaat tgtcttgtat ttctattaat gtctctaaat taccagcata agtcaacaag
    11101 tctaggttaa caataaaata atctacatac ttgttaagca tataatgtat aaaattactc
    11161 ccaataaatc ctgctcctcc agttatcagt atttttttca tattttttct cctaaatgtt
    11221 aattctaata aatttttatt aacgtcttgt acaaatatct ttaaaacttt tttgtttttt
    11281 gtccttttct gataaaaata tttcttcaat tccttttaaa ggccactcaa tagatatttg
    11341 cttgtcattc catataaagc cattctcaaa ttctgggtaa taataatttg tacatttgta
    11401 actaaatact gctttttctg ataaaactaa aaatccatgt gcaaaccctt ctggaatata
    11461 aaattgtttt ttattcttat cagacaatat tacaccttcc catttcccaa atgtttgtga
    11521 atctttcctt aaatcaactg caacatcgaa aacttctccc tctgtaactc tgactaattt
    11581 tccttgagga tatttaacct gaaaatgcat tcctcttaaa acgccttttc ttgagctaga
    11641 ctcattatct tgaataaaac acatatcaag accctgctct ataaaatcct ttttattata
    11701 gctttccata aaatatcctc tttcatcata aaatacattt ggttcgacta tatataatcc
    11761 ttctatttta gtctttataa cattgatttt tcccattata ataaactccc ttaataaaat
    11821 ttataataaa ttttatctac catattacat atcttcacta gccaatttta atagatattg
    11881 accatattca gtttttatca gtggcttggc tagtttcatt aattgttctc tacttatata
    11941 tccttttgta tatgcaatct cttctaaaca tgctatatac agtccctgtc ttgtttgaac
    12001 cacttcaaca taattagaag catccaatag acctttatgt gtaccagtat caagccaagc
    12061 catacctctt cctagaagtt ccacttttag ttttcctcgt tttagatatt cactgtttat
    12121 agaggttatt tctaattcac ctctatctga cggttcaact agctttgcta tctctacaac
    12181 atcattatca taaaaatata atcctggtat agcataatta gatttaggaa ctgtaggttt
    12241 ttcttctatt gacaatacat taaaatcctt atcaaattct acaactccaa acgaatttgg
    12301 attacttaca tgatacccaa atatagttgc tccttttctt ttaactgcat tctccaacct
    12361 ttcactaaat ccatatccat aaaatatatt atcccctaat acaagagaca ctctgtcatt
    12421 tcctataaat tcttctccta ttataaacgc ttctgcaatt ccatttgctt tctcctgaat
    12481 tgcatatgtt atgttaagcc ctagtgaact tccatctcca aataattctt caaatgcttt
    12541 tatatctctt ggtgtagata ttattaatat atcttgtatc cctgccaaca taagaaccga
    12601 catagggtaa tatatcattg gtttatcgta tattggaagt gtttgttttg atatacattt
    12661 tgttatagga tatagtcttg taccagaccc tcctgctaaa ataattcctt tcatcttttt
    12721 ccatccttaa atttgttttt gtcatattat gattatcgga taaataaaag aaatatttat
    12781 attttttata atatcttatt ttcttttctc aaaataatac atttactttt catttatatc
    12841 atatctttct aaatattctt caatggattc ttcccacttt ctaaaagaat ttaaaccaat
    12901 taacttcaac ataaaattat ccaatacaga atatagtggt cttggagcct tacatttaaa
    12961 ttcgttactc ttaattggat ttacttttat atctatattt tttagtttaa atatcttttt
    13021 ggcaaaatca taccaactac actcaccttc acatgtagca tgataaactc cataatgttc
    13081 tgtttccatg attcttatta taatttttgc taagtctact gtacttgttg gagttccaaa
    13141 ctggtcatta accacattaa cctctttatt ttctaaagaa agttttatca tggtctttac
    13201 aaaattattc ccattaccat ataaccatgc tgttctcaat ataaagtact tatgtgagaa
    13261 ttgttcaaca aatttttctc ccataagttt actttttcca tatacagaat tgggttcagt
    13321 tttattgtct tccctatatg gatatttaga aaaaccattg aatacatagt cagttgatat
    13381 gtgaataagc ttagcattaa ctttttctga tgctattgct agatttctca ctcctaaagc
    13441 atttattttg tatgcaattt cgatattatc ttcacatgca tcaacctttg tatatgctgc
    13501 acagtttaca actacatcag gtttattatg caaaataaaa ttatctacat tagtctgatt
    13561 ggatatgtcc aaatcacttc ttgttgtagc taatataaca tattttggtt ggtttatact
    13621 ttgattgatt gcttctaatt ggttaaccaa ttcttttcct aattgaccat tagaccctgt
    13681 tattaatatt ttcattaatt atgttgccct ccaataaata ttcaatttta cttaataatt
    13741 aattataaca cagcttgtat tttaacttag gttgaactta ttatttctta gataaataaa
    13801 aaagagatgt aatattaaat gattatcatc atattattac atctctttaa atctaaatat
    13861 ctaaattata tattctagct atcaattaaa catcaaagct ttatctaaaa tatttaactc
    13921 cagattcaaa tatcttttgg tctttttcac ctataatatt cttatatact tcctcaccaa
    13981 ttctttcaga atgtcccatt ttaccaaaca ctctaccatc agcactagtt ataccttcaa
    14041 cagcatagaa tgaaccattt ggattaaact caatatcata agtagcttca ttattaaagt
    14101 caacatattg agttgctact tgtccattag caattaattc tctcataaca tcttcactgg
    14161 caacaaactt accttctcca tgagaaattg ctatattatg aatatctcca acattagttt
    14221 gagctaacca aggagattta ttagatgaaa ttctagttct agcaatctta gcttgatggc
    14281 gaccaatatt attgtaagta agtgttggag cactttcact tggaactctt atttctccat
    14341 atggaactaa ccctaattta attaatactt ggaatccatt acagatacct aacattagtc
    14401 catctttttg agttaaaaat tcatttatag cttcttgcac tctaggattt ctaaatacag
    14461 tagctataaa tttaccagaa ccatctggct catcaccagc actaaatcca cctggtaaca
    14521 ttattatttg agaagatttt atttcgttta ctattgtatc tatagaatct tctatgtctt
    14581 tataagttaa attcttaaat actcttatac ttgcattagc tcctgctctt tcaaatgctc
    14641 ttgcagagtc atattcacag tttgttccag ggaatgctgg tataaatact cttggagtag
    14701 ctatacttaa tgatgatttt ttagcttctc cttgtgatat ataacttata gtttctatct
    14761 ttgattttac ttcttctgtt ttagttggga atataggctc taaagtacta caatgtgctt
    14821 tatataattc atctaatgca agttcttcac ctttgataaa tatactagct tctttaactg
    14881 tacttccaat cacaacataa ttgtatcctt ctaacatact taaatcatca tttgctaatt
    14941 caagtactat atttccataa ctagcctcaa ataatttatt atctgtaaat gctttttcag
    15001 cttcttcact aaacttaaat cctattttat taccaaaagc cattttactt attgcttcac
    15061 ctacacctgc aaatcctaat gcatatgttg ataaaacttt atttccatgt ataagttctc
    15121 ttactttatc taagtttctc tttaattcct caaaatctac aacatcattt tctgccttgt
    15181 ttacacataa cattactact tttgagtctg cttttttaaa ttctggagat actactttct
    15241 tcgcatctac tgtgtcaaca gcaaatgaaa ctaatgttgg tggaacttca atatctttaa
    15301 atgtaccaga catactgtct tttccaccta tagcaggtat ctcaaattta ctttgtgcat
    15361 aaaacgctcc taaaagtgct gagaatggtt taccccattt ttctggattg ttaccaagtt
    15421 tttcaaaata ctcttggaat gtaagtcttg ttgtactata atttcctcca atagcaacca
    15481 atttacacac agattctact actgcataca aggcaccatg gaatgggctc cattttccta
    15541 cctttggatt gtatccataa gtcattattg tagaagtatt agtttctcct ccaagtactg
    15601 gtatcttagc aaccatacct tgtgttggag tcgcttgata ctttcctcca aatggcataa
    15661 gtactgtatt accaccaatt gtattatcaa acatctctac taatcctttt tgagaacaaa
    15721 cattaaggtc agatagtact tttgtaaact tgtctttcat acttgcacac ttaacatctt
    15781 ttactatttc attagagcta aagaatgtat tttcttcatc tactttagta acatgaacat
    15841 cagtagtttg ttttactccg tttgtatcta aaaactctct atttatatct acaattgctt
    15901 ttccattcca gaacattctt aaatatcctg tatctgttac tgtagctaca tgcgtagctt
    15961 ctaagttttc ttctactgct aattgtataa atttatcttt attttctttt tttatggcta
    16021 ctgccatacg ctcttgtgac tctgaaattg caagctcagt tccatcaagt ccatcatatt
    16081 ttttaggaac taagtctaag tttatatcta agctatcagc aatctctcct atagcaacac
    16141 aaactccacc tgctccaaaa tcattacatc tttttatcat ttgagcaact tctttatttc
    16201 taaagaatct ttgtattttt ctttcgttag gagcatctcc tttttgaact tctgcactac
    16261 aagttaagat tgactcttca ctatgttctt tagatgaacc agttgctcct ccacagccat
    16321 ctcttcctgt ttttcctcca agaagaacga ttacatctcc tgcttcaggt ctttctctta
    16381 ctacattctc ttttggtgct gctgctataa ctgcacctat ttccattctc tttgcaacaa
    16441 agttttcatc atatacttct gcaacttgtc cagttgtaag acctatttgg ttaccatatg
    16501 aactatatcc atgagcagct tctgtagtta tttttctttg cataagtttt ccaggtaaag
    16561 tatcttctaa agtcgttctt gggtcagcac ttcctgtaac acgcattgct tgataaacat
    16621 aacttcttcc tgataatggg tctcttatag ctcctcctaa acaagtagct gctccaccaa
    16681 atggttctat ttcagttgga tggttgtgag tttcattttt aaacattact agatattttt
    16741 ccatcttacc atcaacttca acatctacgt ttatactaca tgcatttatt tcttcacttt
    16801 catctaggtc atttaatttc ccatttttct ttaattcttt tactgcaaca gtggctatat
    16861 ccattaaaca tatatcttta tgtctgttca catatacatt gtctcttgag ttaagataca
    16921 tttgatacgc ttcttttact atatcattaa acttaccatc ttctatcttt acattttcta
    16981 tttcagtcat aaaagtagta tgtctacaat gatcagacca ataagtatct aatactttta
    17041 tttctgttat agttggattt ctcttttctg tatctttaaa gtatttttga acgtgttgta
    17101 agtctcctaa agtcattgct aatccttttt cacttacaaa tgttcttaat ccattttcat
    17161 ctaaatctat aaatccatct aatacttcaa ctgttgttgg tatttcagtt tccattttta
    17221 acgtttctgg tttctctaaa gatgcttctc tactatctac tggatttata cagtaatctt
    17281 ttattttaga aaactcttca tcagttattt tgcctgataa tatataaact tttgctgtat
    17341 taatagcagg tcttatccct tgatttacaa tttgtacaca ttgagctgcc caatcacctc
    17401 tttggtcgta ttgaccagga agaaattcta ttgcaaatac tctttcatca tttaattttg
    17461 gtatttcttc ataatatact acatctaaat ttggttcaga gaatattgtc tttgctgcat
    17521 tttcataaac ttcttctgat attccttcta catcatatct atttaatatt cttaaatttt
    17581 ctatattatc tatgtgtaaa ctttctacta agtctttttt taaagcttta gcctcaaggt
    17641 caaaaccttc tcttttttca accaatactc ttctaaccat tgagtcttta ttttcagtat
    17701 tcaacatacc ttatcctcca ttttagaaaa attatcttcc tatgtctgtt ctatagtgca
    17761 ttccttcaaa gtttatcttc tttatgtttt cataaacttt ttctgctgca tccttaactc
    17821 tagttgactt tgcagttata ccaattactc ttcctccatt ggtaaccaaa ttaccatcaa
    17881 acatcttagt gccactatgg aatactacta tatcatcatc caagttttca agaccagtta
    17941 taattttccc tttttcataa ctgtctggat accctcctga tgtaagcata acacatacag
    18001 cttcatcatc actatagttt atttctatat cttttaactt attatctagt atagcttcca
    18061 ttatctcatg taaatctgtt tctaatctaa ataaaacaga ttgtgtctca gggtctccaa
    18121 atcttacatt atattcaagt actttttctc catcttcagt tatcataaga ccaacaaata
    18181 aaataccttt aaaattaagt ccatcttttt tgaaaccttc taaagttttt tctaatactg
    18241 tctcttttac tttatttgct aattcttctg tatatatttc actaggtgaa aaagttccca
    18301 ttcctccagt gtttggacct tgctcatagt tgtttacttt tttatggtct tttgcacttg
    18361 ccataggaac tattgtatca ttgtctacaa atgctagaat tgaagtttct attcctttta
    18421 aaaactcttc aattactatt ttatctccag cagctccaaa cttcttatct gacatcattt
    18481 cttttaaagt tgctatagca tcttctctat tttcaggtat tacaacacct tttccagcag
    18541 ctaatccgtc cgcttttatt actactggat atccaaaact atctatttct gatatagctt
    18601 cttctaagtt tgtatattct ttatattttg cagtaggtat gttatgtttt atcataaatt
    18661 cttttgaaaa agctttactt ccttcaagtt gagcacattt tttattaggt ccaaatactc
    18721 ttaatccttc tttttcaaac tcatctacta ttcccataac tagtggtact tctggtccta
    18781 ctattgtcag acctatttca ttttctttgg caaattttaa aagttcttct atattagtat
    18841 cacctatatt tacacattct gctacgtttg caattcctgc attacctggt gcacaataaa
    18901 ttttttctac atttttttct ttgcttagtt tccagcatat agcatgctct cttccgccac
    18961 cgcctacaac caatatcttc ataatatcct ccttagtgtt tgaagtgtct tattcctgta
    19021 aataccataa ccatatcata cttgtcacaa gcttctattg aatctttatc ttttatagag
    19081 ccacctggtt gaactactgc tgatattcca tattcatgag ctaatgttac acaatcatca
    19141 aatgggaaaa atgcgtctga cgccaaaaca gctcctgtaa aatctttatc tttgttattt
    19201 tcaagagcat tttttaatgc ccaaattctt gatgtttgtc cacaacctaa agctagagtt
    19261 tgtccatttt ttactactgc aattgcattt gatttcatat tttttactac tctcatacca
    19321 aattccatgt ccttaagttg tgcatctgtt ggtttttcct ttgttacatt ttcacttttt
    19381 tctgctaata tattgtttct atcttgtatc aataattttc catctaaata tttcatttca
    19441 tatggttgta aactattttc tattttagct aattttaata ttcttagatt tttcttttgt
    19501 ttaagtatct ctaaagcttc tggttcaaaa tcatatgcta ctactatttc taagaatatt
    19561 tcatttaatt tctctgctgt agctttatct atagtagaag ttattcctac tattcctcca
    19621 aatattgaaa ccttatccgc ttcataacat tttgtatatg cttcaaaagc atcttttcct
    19681 aaacctaccc cacatgaatt agcatgtttt atagctactg aaactacttc ttcactatct
    19741 ttaaattctc tcattacttc taaacatcca tgtaaatcat ttaagttgtt aaaagaaagt
    19801 tctttaccgc ctaattgctc ataatttaag attggatttt ttgcatttga ctgtgaatat
    19861 aagaaaccat tttgatgtgg attttctcca tatcttaaag tttgttcttt ttggaaagtt
    19921 aaatttaata tgtcaggata cgtatctcca acttctccag caaaataact agatattaac
    19981 gcatcatatc ttcctgtagt tgagaaagct ttatatgata atttttttct gtcttctaat
    20041 gtcattgtat ctgtttttaa tttttctatt atagaatcat aatcttttat atctactact
    20101 actattacat ccttatagtt tttggcagca gaacgtatca tagatggtcc accaatatct
    20161 atattttcaa ttatttcatc atgacttttt ccagctttta aagttccttc aaaatcatat
    20221 agatttacag ctactaaatc tattgaatgt attttgtgtt catttacagt ttctacatga
    20281 gattctttat ctcttttata aagtatacca ccatgtatat atggatttaa tgtttttact
    20341 cttccatcta atatttctgg aaaatttgta acatcttcaa cttgcattac attaacacca
    20401 ttttctttta atgttttaaa tgtatttcct gtagatataa tttcataatc taatttattt
    20461 aactctttag caaattccac tacaccagtc ttgtcagtta cacttattaa agctctctta
    20521 ctcatttata aacactctcc taccttgaag ttttaattta ttttcacaaa aaagacttat
    20581 actttctttt aaaatcctat gttcaacttc taacactctt tttgcaagtg tctttgcatc
    20641 atcatcttga tttaccttaa ctacatcttg cattatgatt ggtccagtat cagcaccttc
    20701 atctacaaaa tgaactgtag caccagttac tttagctcca taatctataa caccttgatg
    20761 aactttttct ccatagaatc cagctccaca aaatgaagga attaatgatg gatgtatgtt
    20821 tatcattttg tttctaaact cgttaaccag ctttgggctg attattttta aataaccagc
    20881 caaaactact aaatctattt tattttcctt aagaatttct attatcttgt cttcatcagt
    20941 ttcacaaatt gcttttatgt tatgattttt agctctctct agcccataag caccttgctt
    21001 acttgagata actactttaa cctgaccttt tatttctcca gactcagtac catctataac
    21061 tgcttgtaaa tttgttcctc caccagatat taaaactcct atatttagca taattctaca
    21121 ccttcatgac tatctactac ttcaccaatt atataagctt tatcttctaa taattcacta
    21181 tattttttat ctacataagc agcattgtca ttttctctat tatttataaa gtttacaaca
    21241 tcatcagcat tttctttatc tactattaaa actagcccaa tacccatgtt aaaactctta
    21301 tgaagttctc tctcatcaac agcattaaaa ccttctatca ttttaaatat aggaggcttc
    21361 tcccaagatt ttttattgat atctagtcct aaccctttag gtataactct tgttatattt
    21421 tctataagcc ctccaccagt tatgtgagct atagctttta tgtcatgttt agctaataca
    21481 tctaaagcta atttaacata tattttagtt ggtgttaaaa gtgcttctcc aactgtcatt
    21541 cctagttctt caacatattg ttccatttta taattgtaag tttctaaaaa tatctttctt
    21601 ataaaagaaa atccattgct gtgtactcca cttgaagata taccaaccaa tacatctcct
    21661 gatttaacat tgtttccaga aacaatcttt tctttgtctg ctattcctac agaaaatcct
    21721 gctaaatcat agtcatcttc tccatacatt ccaggcattt cagcagtttc tccaccaatt
    21781 agtgcacaac cagacatttt acaaccatct gcaattccac caactatttt ttcgatatgc
    21841 tcaggcacta atttcccaag agctatatag tcaaggaaga ataatggttt tgctccttga
    21901 caaattaaat cattcacgca cattgcaact aaatctattc caacagtatc atgcttgtcc
    21961 atcatctgag ctatttttaa cttagtccca acaccatctg tagatgcaag caaaactggt
    22021 tctttcatac ctacaaaatc ttttaaactg tataatccac tgaagttacc taaatctcca
    22081 actacatttc catcataagt tccttttatt ttacctttta taaggtctac tgctctattt
    22141 ccttcatcta tatctacacc tgattcttta tatgttaaca tgaaagtagt tcctccttat
    22201 caattttctt aactgggtat tctccatcaa aacaagcttt acagaaagta gacttatgtt
    22261 ctgttgcatc taacattcct tctatatcta ggaattttaa actatcacat ccaatatatt
    22321 ctctcatttc ttctacgttg ttacttgatg caattaattt agagcgattt ggagtatcta
    22381 ttccatagta acaagagtaa gctactggag gagaagttat tctaagatga atttcttttg
    22441 ctcctgcttc tcttaaagat tttactaatt gtttagatgt agttcctctt acaattgagt
    22501 cgtctactaa aattatagat tttcctttta ttattgttga aagaggattt aattttattt
    22561 ttactgctat ttctctttct tcttgtgtag gttttataaa tgttcttcct acatatctat
    22621 ttttaactaa gccttcactt atttttaatc cactagcatt tgcataacca atagctcctg
    22681 gccaacctga atctggaact ggaactacca tatctgcctt tacagtttca ttctgagcta
    22741 atctctcacc acatttaatt ctaaattcat atgcatttac attgtctata gttgcatcat
    22801 ttcttgcaaa gtatatgtgt tcaaatatac aacttttctt aactggttta taattttctg
    22861 aataaaaata tgattttagt tctccatctt tgactactat tatctctcct ggctctacat
    22921 ctcttataac ttctccgcca agtatatcta ttgcacaatt ttctgatgca aatatatatt
    22981 catcaccctt tttaccaagt acaagaggtc tgaatccatg tgggtctcta actgcaacca
    23041 attcttcttg actcattatt acaagagcat atgcaccttt tatataatcc attgtcactt
    23101 ttaaactttc tactatatcc cctttgtaat atctagcaag tatatataaa atcacttctg
    23161 tatctgaatt agtttggaac atatatccat cttcttctag catatctttt aaataatttg
    23221 cattaactag atttccatta tgagctatgg ctaattgtct ttttctacaa cttccaacta
    23281 aaggttgaca gttagaaaca tgacttcctc cagctgttga atatctaaca tgtccaatcc
    23341 ctatatttcc ttttaactta gataattcat tttccttaaa aacatctcca actaatccca
    23401 tatctttttt gtacttaatt tctccatcat ctaaaagagc taaaccacag ctttcttgcc
    23461 ccctgtgttg catagaatat aaagaataat atagttcttt agttacatct ttattagagt
    23521 aaatccctaa aactccacac atacatttgc ctcctattta ttattcattc ttgaaagtac
    23581 ttccgtataa ccttctacaa ggtctccaag gtcttttcta aatctgtcct tatctaactt
    23641 ttcatttgta tttacatccc aaagtctaca agtgtctggt gatacttcat ctgccaatat
    23701 tatatttcct tcagaatcct taccaaattc tattttaaag tcaactaact ttaggtttaa
    23761 ttttaagaaa aatgctttta gtaactcatt tatttttaaa gtttcttctc ttaagaattt
    23821 taactcttct ctagttgcta acttcattgc cactgcataa tcatcattta gcattgggtc
    23881 accataagca tcatttttgt agcttatttc aaaaattggc tcatcgaaaa ctacaccttc
    23941 ttcaagacca actcttttac agatagaacc agcagcaata tttcttacta ttacttctaa
    24001 tggtaaaatc tctacttttt taactaacat ttctctatct gataaacttt ttataaagtg
    24061 agtatttata ttattttctt ttaacatttc aaagattatt gttgatatct tattatttag
    24121 tatacctttt gaagatattt ctgctttttt ttctccatta aatgctgttg catcatcttt
    24181 ataataaaca acatattcat tttcattatc tgtagaatat acttgttttg cttttccttc
    24241 atataataac atttctgcta cccccttaaa ttcttgtcgt cttctaacac cttttgtgcc
    24301 atctcttctc tatatgattt caaatcctct tttaattttg ggtattttaa agtcattatt
    24361 tgtaatgcca ataaagctgc gtttaaacct aagtctattg taactgttgc aactgggatt
    24421 ccttttggca tttgaactat tgataaaagt gagtctagtc catccatagt tgatgattta
    24481 ataggtaatc ctattacagg aattaatgtt tgtgaagcta ttacacctgg taagtgtgct
    24541 gcttttcctg ctgctgctat tattacatca gtatcatctt ctatttcttt taggaatatt
    24601 gaaagttgtt ctggtgttct atgagctgat aatgctcttg ctacaacttc tattccatat
    24661 ttttcaagca gttttatccc ttcttctaat tttggataat ctgattttga acccataact
    24721 actgctactt tcattagact tcccctctcc gtttataagt tattttacac tacaaatcat
    24781 tcgtattatt atacgaatta tacaccttaa attttatatt aatatacata tattatcaac
    24841 tcttttttga aattttttaa aaaaaatatt tcttgtaatt ttttcattcg ctacgtatcg
    24901 aactttattt gtgttttttt gttaaaataa aaaacagatt atctcaaaat tggttttcta
    24961 attaaatttt aagcccaata ctctttttta aatcttgtat attatttttt attacttctt
    25021 ttttaattaa tactttggat ttatagtctt gttttttagt t
//
LOCUS       DAJMZY010000055        24476 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.055, whole genome shotgun sequence.
ACCESSION   DAJMZY010000055 DAJMZY010000000
VERSION     DAJMZY010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 24476)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24476)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24476
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.055"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            137..1525
                     /locus_tag="OE968_002158"
     CDS             137..1525
                     /locus_tag="OE968_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219436.1"
                     /translation="MEDKFYAKGNGNNGYIKNLEVCSFNNLDGTCGMFQMALYKRDEK
                     YYLYGCCFGGNKKNGVMISDITDPYNPQFIKHFQMLDPKEYPTTTTPKIQIADDLMIV
                     AMSCGSGPGALVDQAKLANIKCEAGIRIYSLKEDPLNPKFLGYWDCGLKHVMGVHRFM
                     YNGGRYVHLSSDCVGFEGLIYRVIDIINPTNPVEIGKWWRPDQYADGYPNRTFDAGAP
                     HCPEFMDKGWLHGPPFVRDGKAYCGYGGAGLVVLDVEDLTRPRCLGELPFMPAFSSRL
                     AGARTHTALPLPGRDLVVVQNEGERFQFFKPDNITDVQAMNNIHMVDVSDPTKPTLIA
                     QFPYPEVPKDFPYPNFNVAGLGKPGPFGPHNLHEPMDNKPWLEQRGDRVYCCYFHAGL
                     RVYDVSDPYYIKELAYFIPPNPNKTPEESYFPGFPGPRLAVTEDLIVDDRGYIIIDAL
                     DDGFYILKMKED"
     gene            1553..2506
                     /locus_tag="OE968_002159"
     CDS             1553..2506
                     /locus_tag="OE968_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HCP7219437.1"
                     /translation="MKILGISFGTKNGNNDTMCKVALKGAKEAGAEVEFIQMSSINIK
                     HCTGCCACVKTLLSGKGSMCVLKDDFEWLLDKMKDADGIVVSDPIFEEGASGLFHTIM
                     DRFGPRADRGNNIIGTKVAEAIGGKIPDSRMLNDKVISFMGIGGSDWGTRVQCEHAML
                     ALIPMWKVIDNAWFPWAKELVMDDTRLVQVHQIGLNIVEAAKDFEKASYQGEEGVCPH
                     CHNRLFYLEPGTKKAICALCGIVGELDTISGKTIFSFPEEQLGHAHDTLPGKFIHGDD
                     IKKMEGHYAEVRKTQEFKERKTSYNFIETLTKEKQAGVSLG"
     gene            2566..2790
                     /locus_tag="OE968_002160"
     CDS             2566..2790
                     /locus_tag="OE968_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219438.1"
                     /translation="MNEKPSFKQIEVILAVIFLVLTYYKVRLTPAFIVIFIPLYLSYF
                     AVSMIVNQIAIKLLEIRQAREATNYNIGNG"
     gene            2783..3295
                     /locus_tag="OE968_002161"
     CDS             2783..3295
                     /locus_tag="OE968_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1097 domain-containing protein"
                     /protein_id="HCP7219439.1"
                     /translation="MDRKKKEILTLSMGIALLPPLWAVLAPYIGIKTGAVALICAGLY
                     VTNGNKQEDGLKIMFGFWCGDLWAVLAILIMGYMNFNQNLELFLTLSILGFFAVVIAS
                     LFEKIIFLPSWLCGWAIGLTIMTGENIINLQDICIQIAVAMAVGVWYVGAGVDLFTIY
                     ILSKDRKKGN"
     gene            3327..4181
                     /locus_tag="OE968_002162"
     CDS             3327..4181
                     /locus_tag="OE968_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA hydrolase"
                     /protein_id="HCP7219440.1"
                     /translation="MAMGFEFKIMRSLIYVGLAKEEYRPKLMDWLYRHHIPDSISTFG
                     PYCTKYAFYQAYPTPNEGERFGARKMQLTEHYWLVDEHMPEMANRIMTEYMPMDVLRW
                     QGCIPDVENKRVHENAESGDAGRAVGGDNGCPPFIFAFVPINWEEDFRGKGRTVQDGP
                     NYRWQFMIKYPDGISKEEGEKWFYDEVVPYFTNCCYVNRFVSSKIMINYGATAFDRVS
                     ELWFEGEEEWYKAVVEETKSFIKKPEWAQEEEFPYLKPQFNIASVFLGDIATMDAYSQ
                     YRGYIPMR"
     gene            4715..5509
                     /locus_tag="OE968_002163"
     CDS             4715..5509
                     /locus_tag="OE968_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HCP7219441.1"
                     /translation="MYTIGQVSKFLGISRDTLKFYEDKGLVNPKKNDENGYRIYNQVD
                     IYDIATINFYREIDIEIKKIQEIRKSKSINNLELLLEEKEQIILKEIEYKKLLLKKVQ
                     LVKEDCDKIKTYFGKYTIKEMKPLEVKGKIKHVTNYEEYEALKENTNNLKKAVTLTDL
                     RRVINFNEEGIIEEKFIIVREVDDYNKIIEGEVLSHPNCIYTIIEDGRWSTGGENIDN
                     KVEDRLREIAIENECELLGIVYVNILLTTYEEGIERIFLEIYAPIK"
     gene            5613..6419
                     /locus_tag="OE968_002164"
     CDS             5613..6419
                     /locus_tag="OE968_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HCP7219442.1"
                     /translation="MRTEKSLKRPIASFIILTNIIFLPLFLLVVVTIMLKLPTVISDI
                     ALCISAWSSTFAFMILFKKIYPGKKFLVHVKDRFRNKLKFSTVSIIISIQVLIAVVVI
                     FILASKNHGIMPNFTVSSWGAFIYLFLKNLFAGSLGEELGWRGFVQNHLQKRHSPLKA
                     SITVGFWWGMWHLPIWFTTGFKGLDLIKYIIFFMIAIISISIIMTTFYNLNKTLIIPI
                     AIHQLFNFLIGIINEDLIELINYYAMLYLIFAIALIVINPGNVLYKNIRE"
     gene            6481..7002
                     /locus_tag="OE968_002165"
     CDS             6481..7002
                     /locus_tag="OE968_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003374619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HCP7219443.1"
                     /translation="MVLLIVDAQKLITNERLYKFNEFVVNVENLIDTARKNNIEVIYV
                     RHDDGVENELTKGKNGFEIYEKFKPCNGEKIFDKKVNSAFKETGLLEYLTNNGEKDII
                     IAGLQTDYCIDATIKCGFEHGFNIIVPAYSNTTVDNFFMSAEQSYKYYNEFIWNERYA
                     KCISLEETLRKMK"
     gene            7417..9504
                     /locus_tag="OE968_002166"
     CDS             7417..9504
                     /locus_tag="OE968_002166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HCP7219444.1"
                     /translation="MVVDKEIVSILQILLNSTLITTNGLQEESNSSKRQITYRINKIN
                     DMLKVKNVPLICLRADKDIIVRKETKKAIKEILEKNYSKNTYYFSKTERLLYMYLMLF
                     INMEDISINHFINSIKVSRSTVNLDFKDLIPELEKKNIKVKNNRINGYYIVGNEMEIR
                     RVLIKNIIETLSNEKSSRVFDIFIKEYNLDSFEEAKKIILKLIKKYEITFVEDRLIEF
                     IYIFIFLKARMYSTRIVTQENVDIPNISVMSSMKEYKFAKELLEVYGSEDKIKPHNIM
                     YISAWILGISVGNYEEDTEDKDVISKIVNKMMTKFGYLSGVYYISQEKIFKQLYSHFR
                     PAYYRLLFKLPIYNPICEKVKEEYKLVYRIVSNAMKEFCGLFGEEIQEEELAYLTMHF
                     ATLFSNKKEFDGFRKRIALIVCSNGVGSSAILHAELTNLFPDLHFIPMSESVGLENIS
                     EPVDIVFTTNYNAEGLKTDVPVIKVSPVMTTKEKYKITREVYIQLGDIFLRQPKIDEV
                     MDIIKKYANVTSESILSSELLAYFTQIENFTSKEGEGPMLSEITNETLVKIKVKAKNW
                     EEAIRQSASVLVENNKVTEGYVDAMINSAKASGPYIVITKHVALPHARPEAGSKEIAI
                     GIATLDSPIEFGNNENDPVKYVFCLSAIDNNSHLRAMSELVELLEEDEFFKVLDSAKE
                     AKEIIDFIKTHEL"
     gene            9519..9806
                     /locus_tag="OE968_002167"
     CDS             9519..9806
                     /locus_tag="OE968_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCP7219445.1"
                     /translation="MYKILIACRAGVGSSLMLKIKTQQIIKENNFPIEVEHGSLDSLN
                     GFNGDAVETLIDVAEELKNKNLKFDIIGIHNIVDRNEIKTALEKFLASKEG"
     gene            9833..11104
                     /locus_tag="OE968_002168"
     CDS             9833..11104
                     /locus_tag="OE968_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIC"
                     /protein_id="HCP7219446.1"
                     /translation="MEFIISLLSTPAVLLGVVACIGLILQKKSAVEVFTGSSKTLIGF
                     LIFGIGASAMTGALQNFNKLFQHGFGITGVIASPEAATALAQGTYGFAVSCTLILGFI
                     LNLVFARITKFKNIFFTTGHSLFFSCVLVLIMKAHGFDNTITILIGGTILGFMSAALP
                     QFCQPFMRELTGGDEQAIGHFNMIGYGLSGYIGRLFSKHKDDTTETIEFPKWLSMFRD
                     FLMGLSIVMLILFYIATLKAGQAFTQEIAGSTHWLVFPLIEAFTFVAGMSILMSGVRM
                     FLAEITAAFVIISEKYIPGSRPALDVPTVFPYAPNAVIIGFISAYAAGLLAIAIMASF
                     PSIFPVVIIPAAHICFFSGGTAAIFGNTSGGWRGAIAGSFVVGLLLAFLPVILYPVYG
                     TLGIEGATFPNIDYNVVGSILHNILQFIKPI"
     gene            11162..11761
                     /locus_tag="OE968_002169"
     CDS             11162..11761
                     /locus_tag="OE968_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HCP7219447.1"
                     /translation="MENTLSEFLDNISNELSEFIASIDETSINKACELILEAEKNHGR
                     VHVTGIGKPGHVSGYISSLLSSTGTSAYILHGTEAVHGSSGQVVEGDVVIAISNSGET
                     QELKATLKTLKVNGAKIIGVSGNESSFLKNISDIFLFAGVKQEGDCLNKAPRASILAE
                     TIILQSLSVVLQYAKGLNTQQYLKWHPAGSLGKSIREGI"
     gene            11766..12671
                     /gene="dapA"
                     /locus_tag="OE968_002170"
     CDS             11766..12671
                     /gene="dapA"
                     /locus_tag="OE968_002170"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HCP7219448.1"
                     /translation="MKYKGIICAMITPFDENQNINSQATCQLIDYLIEKGIYGLFILG
                     TNGECHVLTDDEKVEFAKIVINHTNNRVPVFVGTGGNSTREVVDLSKRMEAIGASALS
                     IITPYFVTPTQQELILHYKTIANSVNLPIIMYNMPSKTGINIEPESVRELSKIKNIVG
                     IKDSSGKLDNMKAYIEATKNENFSVFSGSDSLILDSLKAGSQGAVAATTNFLTEIGIS
                     IYENFMKGDLEEAQKAQSSIEELRRILKLGTIPSVMKKTIVLNGINVGTARLPVTEPT
                     GEVLEEIKRVVENYRTILNKSSENR"
     gene            12777..13409
                     /locus_tag="OE968_002171"
     CDS             12777..13409
                     /locus_tag="OE968_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketohydroxyglutarate aldolase"
                     /protein_id="HCP7219449.1"
                     /translation="MKKMNITKRMSECGALAIVREENLNRACEIAEGCIKGGITVIEM
                     SYTLNNAGEIIQGLNKKYGETLCVGAGTVLDSETARHAILHGAQFIIAPNYNEGVAKI
                     CNRYQIPYAPGCTSLTEAVDALSLGATFIKAFPISDFYGPKLVKVFKTPIPDMPVLAS
                     GGINIENLHIWLENGVDVCGFGGLLTKGSVEDIAKNAKKIREIIKNIRKI"
     gene            13887..16394
                     /locus_tag="OE968_002172"
     CDS             13887..16394
                     /locus_tag="OE968_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HCP7219450.1"
                     /translation="MKEDIRLHRMCKKEQATKNEVISEDILKSMSIGVSKHFLDDSFT
                     IIWGNTSFYQLLGYTEEEFLVKFSSLKDYYEQNLYHFESMKNHFLEAYHHGEKSIEYQ
                     ICISANNGDPVWVIMTGILIESQDNEKSMVYILYSKINELKIKQEELSDMEKESTENF
                     KWMMSEYAGNVYISDMDTYELLYLNKHSCNTLQASANELIGRKCYEVIQGRTSPCPFC
                     TNSYLKKDDIYEWEFYNKKLKRTFIIKDRMLNWQGRRVRIELSYDMYSAEYKLAKKDQ
                     ERESILKTIPAGMVRLDARDYLTILWCNDIFLNMIEYTKEQFAEELNNQCGYLFSEDY
                     KRSKKLAQDLKESGDNVVFEAKIYTRSREERIWTVTLCYISGEDSWDGIPSFYSIGID
                     ITKERKQIEKLQHISEKDALTGIYNRAETERQIKKYFEKNLNVMGALFMIDTDNFKQI
                     NDTEGHMIGDIVLTEMASGMKKIMRDSDVVGRIGGDEFTIFMKNISSVKDAEKKAEEL
                     LYMFRHLFQKEKSFLKVTCSIGIAIYPKDGTTFKEIYARADKALYQAKNMGKNNYVIY
                     NQDYFKELEEFDCSSLGTVIDSEKQYAEYPDNLTRYIFRMLYQTDDIDQAINMILEVV
                     GKQFDVSRVYIFENTEDGRYTSNTYEWCNEGISSQMAYLQNSNYQDYEDYEKLFEDEL
                     VFYCRDIHTLSPKLEELFSSQGIHSTLQCAYKEDRVFSGFVGFDECTGLRLWSQEEIS
                     TLSLISQIISMFLQRKKNNKLNQQIQQYQNILDNIDQCICVINKENNFLLYVNKKFKN
                     TYSKFQIGQPYYLDSIDIHKISIIWNKKEAYLCTSTI"
     gene            16736..18898
                     /locus_tag="OE968_002173"
     CDS             16736..18898
                     /locus_tag="OE968_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HCP7219451.1"
                     /translation="MKKIIYVLFTIELLIVSLLGLNIVKDNEINNILYNETTSISVMF
                     KDYKKLNKNYSKWIKDIADENNVTISKYVFNNNEKLSIYTTDTSLNNNIKLKSGKFPN
                     TNSNEFISNINTNNSNQVGKFSTMSKDISILIRDFGKISEVGESGILYISTQNEDTIN
                     KILRELNVDRSIFVARLHDRYVNSNLYLNPSIIRDLILIILCFLATIIHYSISVSREA
                     SILRLNGYSKLDIIARVIKNILRIMILSSVTALLIYIIYILKLNIGVRACLYFAMFSI
                     ICILINILISILIVGFNSRSSKYVLSLNGKKSYGFVNIMHFTLKIVFVSFLILSINNC
                     ILNYNMLQTQLGNLSEWDKAKNVYNLTLKDTGEQSLGKEEVIKNAKIKGFYKNLVEEK
                     DAFLIDSTNFEKLEDGSYMYEINSKGKNPEVSQYGKNIKINKNYLKVNPIYSNGKEIF
                     NLIDYDDKTINLLVPKKLQVHENEIKKEFRELFYFEKIEVENMYNKELNRALNKTKKS
                     DLNVNIIYVDNNQSYFTYNSLVMDDNRNLIDDPIAIVDIDNIDDSFYLSYISRCVYFN
                     SKKLDALADISSIIEAQGVEAHIQSLHAVYNEYGLEINKLEKYLNSEIFTIIIIAISN
                     LMITYNIVASYYERNKYKLYIKKIFGYSTTARSMLLIVSLILTNIIPIGIISTRVDLS
                     NNIILFGLLILVIEVIVSIVLDKIISNSSFNKIIKGEH"
     gene            18903..19520
                     /locus_tag="OE968_002174"
     CDS             18903..19520
                     /locus_tag="OE968_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCP7219452.1"
                     /translation="MISLINISKKFKDKSIIDKFNLEISKGEFVAITGNSGSGKTTLL
                     NIMGLLEKPNSGDIIINNIKNPNSKQIRILQRDFYGYLFQNYALIENENVENNLKIAL
                     KYQKNINHNKKINYALESVGLRKYNKKKIYELSGGEQQRVALARVILKECEVIFADEP
                     TGNLDKKNRDIVFDILKSLNKNGKTIVFVTHDLELSEQADRVIKL"
     gene            19709..20053
                     /locus_tag="OE968_002175"
     CDS             19709..20053
                     /locus_tag="OE968_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HCP7219453.1"
                     /translation="MENLPNCPKCNSEYTYEDGTLLVCPECSHEWALGLGAEEDSNII
                     KDVNGNVLNDGDSVTVIRDLKVKGSSSSIKIGTKVKNIRLIHDSSDGHDIECKIDGFG
                     AMKLKSSVVKKA"
     gene            20623..21489
                     /locus_tag="OE968_002176"
     CDS             20623..21489
                     /locus_tag="OE968_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HCP7219454.1"
                     /translation="MIDIHKNIYDNKLFEELKIDCKKCFGLCCVALYFSASDGFPIDK
                     ESGKPCINLQPDFKCSVHNSLMKRGFKGCTAYDCFGSGQKVAQVTYKGIDWMQSSELT
                     NQMSEVFLIMRQLHEMLWYLKEASVLNISDTIKSKIDLIIEETEKITNMSPEQIINLD
                     IISHRIKVNLLLSQASESVMGKVKSFIKTSTLKNMKKLSKNIDLIGADLRKINLIGAD
                     LRGRFLIAANLRNTDLSGANLIGADLRDCDIRGANLENSIFLTQLQVNTAKGDSSTKL
                     PASLIRPKYWEK"
     gene            21602..22006
                     /locus_tag="OE968_002177"
     CDS             21602..22006
                     /locus_tag="OE968_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YmaF family protein"
                     /protein_id="HCP7219455.1"
                     /translation="MSYQNYKCERDYVYDDYKYNKCNKCYNDYEEMTHVHEYSESVKL
                     AEECEDRHNHRAAGVTGEAIPINGGTNHVHKINDNVDFLDHFHKICVTTGPAIRIPGT
                     DKHIHLICGETTVNDGHCHKFLFTTQIEAPLV"
     gene            22173..22622
                     /locus_tag="OE968_002178"
     CDS             22173..22622
                     /locus_tag="OE968_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCP7219456.1"
                     /translation="MKSGIILEMKQINSTEYDEMLQVWESSVRATHDFLTEKDIESLI
                     PLVEIGLKEVENIVCIKDNDIIKGFIGIDKDKIEMLFIEDKYRGNGIGKKLIKYAIDK
                     YNVKYVDVNEQNKKAVGFYIHLGFKVFDRSEIDGQGNPFPILHMKLI"
     gene            complement(22778..23155)
                     /locus_tag="OE968_002179"
     CDS             complement(22778..23155)
                     /locus_tag="OE968_002179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HCP7219457.1"
                     /translation="MLTPYLIFNGTCEKAFNFYAEAFGGGKTIFARLDSNPNNPIMHA
                     SVTFTKYEGCIMGADTDKPVVISGMAICVVLPSREAIEEISVKLAEGGTLVQEFLPHP
                     PPHQNDGAAEVLDRYGYTWYLST"
     gene            23417..24334
                     /locus_tag="OE968_002180"
     CDS             23417..24334
                     /locus_tag="OE968_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2268 domain-containing protein"
                     /protein_id="HCP7219458.1"
                     /translation="MVNMNIIEIRSDKIYKKIMDAPINKKEDIYRYELMKPFEFKWKC
                     MNVPIVARQKGGYDVIIASEMLGVLSPKDIDEKQKKNINVLSADKIWATCKETIENSI
                     NAFIKEGYDLNIKDYKYSILLANPNSPYTILSDGYWGDGGIPGYIFLSLVPNEYTINR
                     LPVLIAHECNHNIRFQFIEWNNNITLEEMMINEGLAENFATWMFGEEMLGPWVSRTDI
                     ETLNTYIKPIIKSALKETGFQNITSYLYGDDIAKMQGYFPVGLPYCAGYACGYYMIKY
                     YLEKTNKSIIEATLLPYSEIIEAVKEFWE"
BASE COUNT         9548 a         2664 c         4252 g         8012 t
ORIGIN      
        1 ttacattaga ttttataaat ttattaataa gaataactta tatattccaa tgaaaacgat
       61 attggattta agtaagtttg tctcataaaa tgaaagtata tcaattgata atactttaaa
      121 taagaaggga gaaaaaatgg aagataaatt ttatgcaaaa ggcaacggaa ataacggata
      181 tattaaaaat cttgaagttt gttcctttaa taacttagat ggaacttgtg gaatgtttca
      241 aatggctctg tacaaaagag atgaaaaata ctatttatat ggatgctgtt ttggaggaaa
      301 taaaaaaaat ggagtaatga ttagcgatat tacagaccct tataatccac aatttataaa
      361 acattttcaa atgttagacc ctaaagagta tcctacaaca acaactccca aaattcaaat
      421 agcagatgat ttaatgatag tagcaatgag ttgtggaagt ggaccaggag cacttgttga
      481 ccaagctaaa ttagcaaata ttaagtgtga agcaggaatt agaatatata gtttaaaaga
      541 agacccttta aatcctaagt ttttaggata ttgggattgt ggcttaaagc atgtaatggg
      601 tgttcataga ttcatgtaca atggtggaag atatgtacat ttatcaagtg attgtgttgg
      661 ctttgaaggt ctgatttata gggtcataga tataataaat cctactaatc cagtggaaat
      721 aggtaaatgg tggagaccag accaatatgc agatggatat ccaaatagaa cttttgatgc
      781 aggagcacct cattgcccag aatttatgga taaaggatgg cttcatggac ctccatttgt
      841 aagagacgga aaagcatatt gtggttatgg aggagctggt ttagttgtat tagatgttga
      901 agatttaaca agaccaagat gcttaggtga attgccattt atgcctgcat tttctagtag
      961 acttgcaggt gcaagaactc atacagcatt accattgcca ggaagagatt tagtcgttgt
     1021 tcaaaatgag ggagaaagat tccagttctt taaaccagat aacattacag atgttcaagc
     1081 tatgaataat atacatatgg ttgatgttag tgacccaaca aaaccaacat taattgctca
     1141 atttccatat cctgaagttc caaaagattt cccttatcct aactttaatg ttgcaggatt
     1201 aggaaaacca gggccatttg gtccacataa tcttcatgaa ccaatggata ataaaccatg
     1261 gttagagcaa agaggagata gagtatattg ctgttatttc catgcagggc taagggttta
     1321 tgatgtatca gacccatatt atatcaaaga gctagcatat tttataccac caaatccaaa
     1381 taaaacacca gaagaatctt atttcccagg attcccagga ccacgcttgg cagtaacaga
     1441 agatcttatc gttgatgata gaggctacat catcatagat gctttagatg atggattcta
     1501 tatattaaaa atgaaagaag attaaataaa tactaaagag ggagagttga aaatgaaaat
     1561 actaggtatt tcttttggaa caaaaaatgg aaataatgac acaatgtgta aagttgcact
     1621 taaaggtgcc aaagaagcag gggctgaagt agaatttatt caaatgtcat ctattaacat
     1681 taaacattgt actggatgtt gtgcgtgtgt taaaacttta ttatctggga aaggtagtat
     1741 gtgtgtatta aaagatgatt ttgaatggtt gcttgacaaa atgaaagatg cagatggtat
     1801 agtagtttca gaccctattt ttgaagaagg ggcatcagga ttattccata ctataatgga
     1861 ccgttttgga cccagagcag atagaggaaa taacattata ggaacaaaag ttgcagaagc
     1921 tataggagga aaaattccag attcaagaat gcttaatgat aaagtaatat catttatggg
     1981 aataggaggt tctgactggg gtacaagagt tcaatgtgaa catgctatgc tagctctcat
     2041 accaatgtgg aaagttatag ataatgcttg gttcccatgg gcaaaggaat tagtaatgga
     2101 tgatacaagg cttgttcaag ttcatcaaat tggtttaaat atagttgaag cagcaaaaga
     2161 ttttgaaaaa gcttcatatc aaggagaaga aggtgtatgt ccacattgcc acaatagatt
     2221 attctacctt gagccaggta ctaaaaaggc aatttgtgct ctatgtggta tagttggaga
     2281 gttagatact ataagtggaa aaactatatt tagttttcca gaagagcaat taggtcatgc
     2341 tcatgatact ttaccaggta agtttataca tggtgatgat attaagaaaa tggaaggtca
     2401 ttatgcagaa gttcgtaaaa cacaagaatt taaagaaaga aaaacatctt ataattttat
     2461 agagacatta actaaagaaa aacaagctgg agtttcatta ggataataat taaaatacta
     2521 agactctttt ttaagggatg ttagatgtta taggaggctt attgtatgaa tgaaaagcca
     2581 agttttaaac aaattgaagt tattttagca gttatttttt tggtacttac atattacaag
     2641 gttagattaa ctccagcatt tattgttata tttataccac tatatttaag ttattttgca
     2701 gtatctatga ttgtaaatca aatagcaatt aagctattgg agataaggca agctagggaa
     2761 gctactaatt acaatatagg aaatggatag aaagaaaaaa gaaatattaa cactgtctat
     2821 ggggattgct ttactacctc ctttatgggc agtattagca ccttatatag gaataaaaac
     2881 tggagctgta gcactaatct gtgcaggatt atatgtaact aatggtaata aacaagaaga
     2941 tggattaaaa ataatgtttg gtttttggtg tggagattta tgggcagtgt tagccatttt
     3001 aattatggga tatatgaatt tcaatcaaaa cctagaatta tttttaacac ttagtatatt
     3061 aggttttttt gcagttgtaa ttgcatcctt atttgaaaaa ataattttcc taccatcatg
     3121 gctttgtggt tgggctatag gtctaactat tatgacaggt gaaaatatta ttaatttaca
     3181 agatatttgt attcaaattg ctgtagctat ggcagtagga gtatggtacg tgggtgcagg
     3241 tgtagatttg tttacaatat atattttgag taaagatagg aaaaagggaa attgaaagca
     3301 tgtgaatata ctttgattat aggaggatgg ctatgggttt tgaatttaaa ataatgagaa
     3361 gtttaatata tgtaggactt gccaaggaag aatatagacc taagctaatg gactggttat
     3421 atcgtcacca tattccagat agtattagca cttttggacc atattgtact aaatatgcct
     3481 tttatcaagc atatcctaca ccaaatgaag gtgagcgttt tggtgcacgt aagatgcaac
     3541 taacagaaca ttattggctt gtagatgaac atatgcctga gatggcaaat agaattatga
     3601 cagaatatat gcctatggat gttctacgtt ggcaagggtg tataccagat gtagaaaata
     3661 aaagggttca tgaaaatgca gaaagtggag atgcaggacg tgcagtaggt ggagataatg
     3721 gatgtccacc atttatattt gcctttgttc caataaactg ggaagaagac tttagaggaa
     3781 aaggacgtac tgtacaagat ggaccaaact atcgttggca atttatgatt aagtatccag
     3841 atggtatctc taaagaagaa ggagaaaaat ggttctatga tgaggtagtg ccatacttta
     3901 caaactgttg ctatgttaat cgttttgtca gtagtaaaat aatgattaat tatggagcaa
     3961 ctgcttttga ccgtgtgtca gaactatggt ttgaagggga agaagaatgg tataaagctg
     4021 tggttgaaga gacaaagtcg tttattaaaa aaccagaatg ggcacaagaa gaggagttcc
     4081 catatttaaa accacaattc aatatcgcat cagtattctt aggtgatata gcaactatgg
     4141 atgcatactc acagtatcgt ggatatatac caatgagata aaaattatag tttgtgataa
     4201 gtagagaagg catttactct tactggtaga agaagactta ttgtatcctt aaaagtaggt
     4261 gaatatatag ttttatattt aaatttatat aaaactaaga ctaataaata tgaaacaata
     4321 gaattagaat aatttgataa tatttgttaa aagagcattt agaatgtgtt taaagattaa
     4381 gatattcctt ttatggtagc agatagttga aataataaaa ctgttatcat gaaaggaata
     4441 tttttatgta taggaaattt ttaaaaataa aagttaaata tgtttaagaa catcttaaag
     4501 tgaaagaatc attgttagaa atatgtagac aatatagtat ttataacgta tcatattaac
     4561 aagtttacac ttggattatg aaataaaaag agtaattcta aaggttgtaa atactatgct
     4621 gactttgata cttcaaagtt taggtgattt tgtaattgtt aatagaaata cgtttaatga
     4681 gcataaagaa tttatctaat aataggagaa tataatgtat acaattggac aagtatctaa
     4741 atttttagga atatctagag atacactaaa attttatgaa gacaaaggat tagtaaatcc
     4801 taagaaaaat gatgaaaatg gatatagaat atataatcag gttgatatct atgatattgc
     4861 aacaataaac ttttatagag aaattgatat agaaattaaa aagattcaag aaataagaaa
     4921 aagtaaaagt ataaacaatt tagaactctt actagaagag aaggaacaaa tcatactaaa
     4981 agagatagaa tataaaaagc ttctcttaaa aaaggttcag ttagtcaaag aagattgtga
     5041 caaaatcaaa acatattttg gaaaatacac aataaaagaa atgaagcctt tggaagtaaa
     5101 aggtaaaata aaacatgtta ctaactatga ggaatatgaa gccttaaaag agaatacaaa
     5161 caacttaaaa aaagcagtta cattaactga tttaagaaga gtaataaatt ttaatgaaga
     5221 aggtataata gaagaaaaat ttataattgt aagggaagta gatgactaca acaaaatcat
     5281 agaaggtgaa gttctatctc atcccaattg tatttatact attattgaag atggcagatg
     5341 gtcaactgga ggagaaaata ttgataataa agtggaagac agattaagag aaatagcaat
     5401 agaaaatgaa tgtgaattac ttggaatagt ctatgttaat atattgctta ctacttatga
     5461 agaagggatt gagcgtatat ttttagagat ttatgcacct ataaaataat ataaaagcat
     5521 tgacctggga cttactcata ggtttaaact catgatataa gcagttataa cttatatagc
     5581 aattaaatat taatttgaaa tgaggattac ttatgagaac agagaaatca ttaaaaaggc
     5641 ctatagccag ttttattatt ctaacaaata taattttttt accacttttt ttattggtag
     5701 tagtgactat aatgttaaaa cttccaacag tgatatctga cattgcgttg tgtatatcag
     5761 cgtggtcatc cacttttgca tttatgatat tatttaaaaa aatttatcca ggtaagaaat
     5821 ttttagtaca tgtaaaagat agatttagaa ataaacttaa attttcaaca gtatctataa
     5881 taattagtat acaagtccta atagctgtag tagttatatt tatattagca tctaaaaatc
     5941 atggaataat gcctaacttt acagtttcat catggggagc atttatatat ttatttttaa
     6001 aaaatttatt tgcaggatca ttaggtgagg aattaggttg gagaggattt gttcaaaatc
     6061 atcttcagaa aagacattct cctttaaaag catccataac agtaggtttt tggtggggga
     6121 tgtggcattt accaatatgg tttacaacag gattcaaagg acttgattta ataaaatata
     6181 ttatattttt tatgattgca attatatcaa tcagtattat aatgacaact ttttataatc
     6241 taaataaaac tttgataata cctattgcaa tacatcaact atttaatttt ttaataggga
     6301 taattaatga agatttaata gagcttataa attactatgc aatgttatat ttaatatttg
     6361 caattgcatt aatagttata aatccaggaa atgtattata taaaaatatt agagagtaat
     6421 atatatcttt atggtaagat ataaagatat tattagaaga acatccaagg aggaataaac
     6481 atggttttac tgattgttga tgcacaaaag ttaataacaa acgagaggtt atataaattt
     6541 aatgaatttg tagtaaatgt agaaaattta attgatacag ctagaaaaaa taatatagaa
     6601 gtaatatatg tacgtcatga tgatggagtt gaaaatgaat tgactaaagg taaaaatggc
     6661 tttgaaatat acgaaaaatt taaaccatgt aatggagaaa aaatatttga taaaaaagta
     6721 aatagtgctt ttaaagaaac tggtctatta gaatacctaa caaataatgg tgaaaaagat
     6781 attattattg ctggtctcca aacagattat tgtattgatg ccactataaa atgtggattt
     6841 gaacatggat ttaatataat agttccagct tattcaaata caactgttga caattttttt
     6901 atgtcagcag aacaatcata taaatactac aatgaattta tatggaatga aagatatgcg
     6961 aagtgtattt cattagagga aacacttaga aaaatgaaat aaaaatagag tatgaattgt
     7021 atatgtacat aagttgattt cataaaaaag gatgttaaat tccaagttaa aaattagatt
     7081 aaatatatta tattatagat aaggcacatc aattttattt taaattaatg tgctttttaa
     7141 ttgtagtaat ttatttataa tcaatatgat ttttattatt taaatcaatt tttcttgagt
     7201 ttctttgtct aaagaaactt tttttattta taaaatctac agttatatta tagtatctat
     7261 tttagatgag tttaattttt gtatcaatct aaaacaaaag ttatacttaa atgaaattga
     7321 aaacgataaa attctcaaat aaaataagta ttgtggaggt gatgaaagaa tccaatgata
     7381 atatgaagac taatcttaat aagaaagtag gggttaatgg tagtggacaa agaaattgta
     7441 tcaattctcc agattttatt aaatagcaca ttgattacaa ctaatggatt acaagaggag
     7501 tctaattcat caaagagaca aattacttat agaataaata aaatcaatga catgcttaaa
     7561 gtaaaaaatg taccacttat atgtttaaga gccgacaaag atattatcgt tagaaaagaa
     7621 acaaaaaaag caattaaaga aattttagaa aaaaactatt ctaagaatac ttattatttt
     7681 agtaagacag aaagactttt atatatgtat ttaatgcttt ttattaacat ggaggatatt
     7741 tcaattaatc attttataaa ttctataaaa gtaagtaggt ctactgtaaa tcttgatttc
     7801 aaggatttga taccagagct tgaaaagaag aacattaaag ttaagaacaa tcgtataaat
     7861 ggatattaca tagttggcaa tgagatggaa attaggagag tacttattaa aaacattata
     7921 gaaactttgt ctaatgagaa aagttcaaga gtatttgata tttttattaa agaatataat
     7981 ttagatagtt ttgaagaggc taaaaaaatt atattaaagc taataaaaaa atatgaaatt
     8041 acttttgttg aagatagatt aatagaattt atatatatat ttatctttct aaaagcaagg
     8101 atgtattcaa ctagaatagt tactcaggaa aatgtagata ttcctaatat ttcagttatg
     8161 agttcaatga aggagtataa atttgctaag gaattattag aagtatatgg gagtgaagat
     8221 aagataaagc ctcacaatat aatgtatatt agtgcttgga ttttaggtat atcagtagga
     8281 aattatgaag aagatacaga agataaggat gtaatttcaa aaattgtaaa taaaatgatg
     8341 acaaagtttg gatatttaag cggagtttac tatataagcc aagaaaaaat atttaaacaa
     8401 ttatattctc attttagacc tgcctactat agacttttat ttaaattacc tatctataat
     8461 ccgatttgtg aaaaagtaaa agaagaatat aaattagttt atagaattgt aagtaatgca
     8521 atgaaagagt tttgcggatt atttggagaa gaaattcagg aagaagagtt agcatatctt
     8581 acaatgcact ttgcaacact tttttcaaat aaaaaagaat ttgatggttt tagaaaaaga
     8641 atagcattaa tagtttgttc aaatggcgtt ggtagttcag ctattttaca tgcagaactt
     8701 acaaacttat ttcctgactt acactttata ccaatgtcgg aatcagttgg attagaaaat
     8761 ataagtgaac ctgtagatat tgtatttact actaattata acgcagaggg tttaaaaaca
     8821 gatgtaccag taattaaagt aagccctgtt atgaccacaa aagaaaaata taagattaca
     8881 cgtgaagtgt atattcaatt aggtgatatt tttttaagac aacctaaaat agatgaggtt
     8941 atggatataa taaaaaaata tgcaaatgta acctctgaaa gtattctttc aagtgagcta
     9001 ttagcttatt ttacacagat agagaatttt acatctaagg aaggagaggg gcctatgcta
     9061 agtgagatta ctaatgaaac actagtaaaa ataaaggtaa aagctaagaa ttgggaggaa
     9121 gctattagac agtcagcttc tgtattagtt gaaaataaca aagtaactga agggtatgta
     9181 gatgctatga ttaactcagc aaaagcatct ggaccataca tagtaattac aaaacatgtt
     9241 gcacttccac atgctagacc agaagctggg tcaaaagaga ttgcaatagg cattgctact
     9301 ttagatagtc ctattgagtt tgggaataac gaaaacgacc ctgtaaaata tgtattttgt
     9361 ctaagtgcaa tagacaataa tagccattta cgtgctatgt ctgagctagt tgaactattg
     9421 gaagaagatg agttttttaa ggttttagat agtgctaaag aagctaaaga aattattgat
     9481 tttataaaaa cacacgaatt ataaaggagg atttaattat gtataaaatt ttaatcgcat
     9541 gtagagcagg agttggctca agtttaatgt taaaaataaa gactcaacaa attattaagg
     9601 aaaataactt tccaattgaa gtagagcatg gttcattgga ttcactaaat ggattcaatg
     9661 gagatgctgt agaaacatta attgatgttg ctgaagaatt aaaaaataaa aatttgaagt
     9721 ttgatataat tgggattcac aatattgttg accgtaatga aataaagaca gcactagaaa
     9781 aattccttgc ttcaaaagag ggataaattt aagatgataa ggaggaatat ttatggagtt
     9841 tattattagt ttgctgagta cacctgctgt tttgcttggc gtagttgcat gtataggatt
     9901 gattcttcaa aagaaatcag ctgttgaagt atttacaggc tcttcaaaaa cacttatcgg
     9961 ttttttgata tttggtattg gtgcctctgc tatgacagga gcacttcaaa atttcaataa
    10021 actgttccaa catggctttg gaattactgg tgttatagct tcaccagaag cagctacagc
    10081 acttgcacaa ggtacatatg gttttgcagt ttcatgtaca ttaattcttg gattcatatt
    10141 aaatttagta tttgcacgta ttacaaagtt taagaatatt ttctttacaa caggtcatag
    10201 tttgttcttt tcttgtgtat tagttttaat tatgaaagca catggatttg ataatacaat
    10261 cactatttta ataggtggaa ctatcttagg gtttatgtct gctgcactac ctcaattctg
    10321 tcaaccattt atgcgtgaat taacaggtgg cgacgaacaa gctattggtc actttaacat
    10381 gattggttat ggtttatcag gttatattgg gcgtttattt tcaaaacata aagatgatac
    10441 aacagagact atagaatttc ctaagtggtt atcaatgttc agagacttct taatgggtct
    10501 atccatagtt atgttaatct tattttatat tgcaacatta aaagctggtc aagcatttac
    10561 tcaagaaatt gctggttcaa cacattggtt ggtttttccg cttatagagg catttacatt
    10621 tgtggcaggt atgtcaatat tgatgtcagg tgttcgtatg ttcttagctg aaataactgc
    10681 agcatttgta atcatttcag aaaagtatat tccaggttca cgtcctgcgc tagatgttcc
    10741 aacagtattt ccatatgcac caaatgcagt tattattggg tttatatcag catatgctgc
    10801 tggtctatta gcaattgcta ttatggcatc atttcctagt atatttcctg tagtaattat
    10861 tccagctgct cacatatgtt tcttctcagg aggtacagct gcaatatttg gcaatacttc
    10921 aggaggatgg agaggggcta ttgctgggtc atttgttgtg gggttattac ttgcattttt
    10981 accagttata ctatatccag tttatggcac tcttggtata gaaggagcaa ctttccctaa
    11041 tattgattac aatgtagttg gttcgatatt acataatatt ttacaattta taaaacctat
    11101 ttaaactaaa ttatataaaa gtatagtcat agttactatg atttcaagga ggatacatct
    11161 tatggaaaat acattatctg aatttttaga taatatatct aatgaattgt cagaatttat
    11221 tgcctcaata gatgagacat ctataaataa agcatgcgaa ttaattcttg aagctgaaaa
    11281 aaatcacgga cgtgtacatg tgactggtat tggcaaacca ggacatgtat cgggatatat
    11341 ttcatcattg ctttcatcta ctggaacgtc agcatatata ttgcatggta cagaagcagt
    11401 acatgggtca agtggtcaag tagttgaagg agatgttgtt attgcaatat caaatagtgg
    11461 tgaaactcaa gagttaaaag caactcttaa gactctaaaa gtaaatggag caaagataat
    11521 tggtgtaagt ggtaatgaga gttcattttt aaaaaatatt tctgatatat tcctgtttgc
    11581 aggtgttaaa caggaaggag attgtcttaa taaagctcct cgtgcttcaa ttttagctga
    11641 aacaataata ttacaatcat taagtgttgt attacaatat gctaaaggtc ttaatacaca
    11701 gcagtatttg aagtggcatc cagcaggaag tcttggaaag tctattagag agggaatata
    11761 attttatgaa atataaaggg attatatgtg caatgataac accatttgat gaaaatcaaa
    11821 atattaattc acaagcaaca tgtcaattaa ttgattattt gattgaaaag ggaatttatg
    11881 gattatttat tttgggcact aatggtgaat gtcatgtatt aacagatgat gaaaaagttg
    11941 aatttgcaaa gattgttatt aatcatacaa ataatcgtgt acctgttttt gttggaacag
    12001 ggggtaattc aactcgtgaa gttgtagatt tatctaagag aatggaagcg attggagcaa
    12061 gtgcattatc tattattaca ccatactttg ttacaccaac acaacaggaa ttaatcttac
    12121 attacaaaac tattgctaat tcagttaatt tacctattat aatgtataat atgccaagta
    12181 agactggaat taatattgaa ccagagtcag tacgtgaatt atcaaagata aagaatattg
    12241 ttggaattaa ggatagtagt ggtaaacttg acaacatgaa agcttatatt gaagcaacga
    12301 agaatgagaa ttttagtgtg ttttcaggct cagattcact tattctggat agtctaaaag
    12361 ctggtagtca aggagctgtt gcagcaacaa caaacttcct cacagagatt ggtatctcta
    12421 tctatgaaaa ctttatgaaa ggggatttgg aagaagctca aaaagctcaa agtagtatag
    12481 aagaacttcg acgtatactg aaacttggaa caattccatc tgttatgaag aaaactattg
    12541 tcttgaatgg aattaatgtt ggaactgcac gacttcctgt aactgaacca actggggaag
    12601 tacttgaaga aattaaacga gtagttgaaa attataggac aatacttaat aaaagtagtg
    12661 agaatagata atataaatag ggaaattaca ctggtatata attaatatat atattataaa
    12721 acatgactaa aattaatgaa taagtaaagt ggtttgatga gtatagaggt gataatatga
    12781 aaaagatgaa tataaccaaa agaatgtcag aatgtggggc tcttgcaatt gtaagagaag
    12841 aaaatcttaa ccgtgcatgt gaaattgctg aaggatgtat aaaaggtggt ataacagtta
    12901 tagaaatgag ttatacccta aataatgctg gagaaataat tcaagggctt aataaaaagt
    12961 atggtgaaac actttgtgtg ggagcaggaa cagttttgga tagtgaaaca gctcgtcatg
    13021 ctatattaca tggagctcaa tttattattg caccaaatta caatgaaggt gtagcgaaga
    13081 tttgcaatag atatcagatt ccttatgctc caggatgtac atcattgact gaggcagtag
    13141 acgcactaag tttaggagca acttttataa aagctttccc aatatcagat ttctatggac
    13201 ctaaactagt aaaggtattt aagacaccaa tacctgatat gccagtttta gcaagtggag
    13261 ggattaatat tgaaaaccta catatatggt tagaaaatgg agttgatgta tgtggatttg
    13321 gtggtttatt aactaaaggt tctgttgaag atattgctaa aaatgctaaa aagattcgtg
    13381 aaatcattaa aaatataaga aaaatttaac atagggctgt atcatagtat cttataatta
    13441 ctatgataca gcctttttaa tattattcaa attaaaaaca gtttacattt ctattatatt
    13501 acatataatt tcagtaattt tatcttaatt tttctatctg gaaaaaaatg atttaaaact
    13561 taagttatga tataatttca ttaaaagaag gcgattttta gtaaatatga gaaaataatg
    13621 tgtttttagg ggaaaagtta aatacagatt taagtgaaca agaatcgata attaagatat
    13681 taaatggtga atagggcatc aaaaaaatta ctaaattaaa agttttagag ggagaatctt
    13741 agcaagtgtg tgtgaaaatt caatttcaaa caaaaaataa ttgtaaatga aatcaattta
    13801 tacacgttga agattcactt ttatcattat attaaaaagc agagtgaatt aaaagtgagt
    13861 ctaaagatag gaggataatt aaaacaatga aagaagacat taggttacat cgaatgtgta
    13921 aaaaagaaca agcaacaaag aatgaagtta tatcagagga tattctaaaa tctatgagta
    13981 ttggggtcag taaacatttt ttagatgatt catttacaat aatatgggga aatacatcat
    14041 tctatcaatt attaggatat acagaagaag aatttttagt taaattttct agtttaaaag
    14101 attattatga acagaatctt tatcattttg aatctatgaa aaatcatttt ttagaggctt
    14161 atcatcatgg cgaaaagagt atagaatatc aaatttgcat ttcagcaaat aatggagacc
    14221 ctgtttgggt aataatgact ggtatattaa ttgaatcaca agataatgag aaatcaatgg
    14281 tctatatatt gtattcaaaa attaatgagt taaaaataaa gcaagaagaa ctatctgata
    14341 tggaaaaaga gagtacagag aattttaaat ggatgatgtc agagtatgct gggaatgttt
    14401 atattagcga tatggataca tatgaattac tatacttaaa taagcactca tgcaatactt
    14461 tacaggcatc agcaaatgaa cttattggaa gaaaatgtta tgaggtaatt caaggtagaa
    14521 cttcgccatg tccgttttgt acaaattcgt atttaaaaaa agatgacata tatgaatggg
    14581 aattttataa taaaaaactg aaacgaacat ttataattaa agaccgtatg ttgaattggc
    14641 aagggcgaag agttcgtatt gaattatctt atgatatgta tagtgctgaa tataaattag
    14701 caaaaaaaga tcaggaaaga gaatcaattt tgaaaactat tccagcagga atggttagat
    14761 tagatgcaag agattatctt actatacttt ggtgtaatga tatatttttg aatatgattg
    14821 aatatacaaa ggaacagttt gcagaggaac ttaataatca atgtggatat ttattttctg
    14881 aagattataa acgtagtaag aaactggcac aagatttgaa ggagtctggg gataatgttg
    14941 tatttgaagc aaaaatatat acacgttcaa gggaagaacg tatatggact gttacattgt
    15001 gttatatcag tggggaagac agttgggatg gaataccatc tttttatagt ataggtattg
    15061 acataacaaa ggaaagaaaa cagattgaga aattacagca tatatcagag aaagatgcat
    15121 taacaggaat ttataatcgt gctgagactg aaaggcagat taagaaatat tttgaaaaaa
    15181 atttaaatgt tatgggtgca ctgtttatga ttgatacaga taattttaaa cagattaatg
    15241 atacagaagg gcatatgatt ggagatatag tacttactga gatggcatca ggtatgaaaa
    15301 aaataatgcg tgacagtgat gttgttggaa gaataggtgg agatgagttt acaattttta
    15361 tgaagaatat ttcctcagtt aaagatgcag aaaagaaagc agaagaacta ttgtatatgt
    15421 tccgtcatct atttcagaaa gaaaaaagtt ttctaaaagt aacttgtagc ataggaatag
    15481 ctatatatcc aaaggatggt actacattca aggaaatata tgcaagagct gataaagccc
    15541 tgtatcaagc aaaaaatatg ggaaaaaata attatgtaat ctacaaccaa gattatttta
    15601 aagaattaga agaatttgat tgttcttctc ttggtacagt tattgattca gaaaaacaat
    15661 acgctgaata tcctgataat cttacacgtt atatattccg tatgctttat cagactgatg
    15721 atatagacca ggcgattaat atgatacttg aggttgttgg gaaacagttt gatgtaagtc
    15781 gtgtttatat ttttgaaaat acagaagatg gtagatatac ttctaatact tatgaatggt
    15841 gtaatgaagg aatctcttct caaatggctt atttgcaaaa cagcaattat caagactatg
    15901 aggattatga aaagcttttt gaggatgaat tagtttttta ttgtcgagat atccatacat
    15961 taagtcctaa actagaagaa ttgttttcta gtcaaggtat ccactctaca cttcaatgtg
    16021 catataaaga agatagagtt ttcagtggat ttgttggatt tgatgaatgc acaggactac
    16081 gtctatggtc acaagaggaa ataagtacat tatcattgat ttctcaaatt atatcaatgt
    16141 ttttacaacg taaaaaaaat aataaactta atcaacagat tcaacaatac cagaatattt
    16201 tagataatat tgaccagtgt atttgtgtga ttaataaaga aaataatttt ttattatatg
    16261 taaataaaaa atttaaaaat acatattcta aattccaaat tggacaacct tattatcttg
    16321 attctataga tattcataag atatccatta tatggaataa aaaagaagca tacctatgta
    16381 ctagcacgat ttaatggtaa agtaaagttt atattggact taaattaaat ttcgttttaa
    16441 ataagatatt attttagttg cttactgaaa agactagaat ctatattaat gaattatact
    16501 aattttatac cactattaaa atattgtttg ctaaaaataa aaaatagcct taaaacagtt
    16561 gattataaaa aattaactgc tttaaggcta tttttatctt tgtgacgaaa tagacacttg
    16621 ccatttagaa tgtgacaata tagtagttgt ttagaaaagg cacaaagcat tatactttaa
    16681 ctaaagtaaa atgtattttg cttttagaat aaaaacaatt aggagggagc tataattgaa
    16741 aaagataata tatgtattat ttacaattga actattaata gtatctttat taggtctaaa
    16801 tatagttaaa gataatgaaa ttaataatat tttatataac gagacaacaa gtatatctgt
    16861 aatgtttaaa gattataaaa agttaaataa aaattatagt aagtggatta aagatattgc
    16921 agatgaaaat aatgtgacta tatcaaagta tgtttttaat aataatgaaa aattatctat
    16981 atatacgact gatacaagtt tgaataacaa tataaagtta aaatcaggaa aatttcctaa
    17041 tactaattca aatgaattta ttagtaatat aaacactaat aatagtaatc aagtaggtaa
    17101 attctcaact atgagtaaag acatatcaat tttaattagg gattttggta aaataagtga
    17161 agttggagaa tcaggaatct tatatatttc aactcaaaat gaagatacaa taaataaaat
    17221 attaagagaa ctaaatgtag acagaagtat ttttgtagca agattacatg atagatatgt
    17281 taactcaaat ttatacttaa atccttcaat aattagagat ttaatactaa ttatcctttg
    17341 tttcttggct acaataatac attattcaat tagtgtgagt agagaggctt ctattttaag
    17401 attaaatgga tactctaagc tagatataat tgctagagtt ataaaaaata tacttagaat
    17461 tatgatttta tcatctgtca cagcattatt aatatatata atctatattt taaaattaaa
    17521 tataggtgtt agagcatgct tatactttgc tatgttttcg attatatgta ttttgataaa
    17581 tattttgata tctatattaa tagttggttt taatagtaga agttctaaat atgtgctatc
    17641 tctaaatgga aaaaaatctt atggttttgt aaatataatg catttcacat tgaaaattgt
    17701 atttgtatca tttcttatat tatccataaa taactgtatt ttaaattata atatgctaca
    17761 aactcagtta ggaaatctat ctgagtggga taaagcaaaa aatgtttata atcttactct
    17821 taaagataca ggcgaacaat ctttaggaaa ggaagaagta attaaaaatg ccaagattaa
    17881 aggtttctat aaaaatttgg tagaagaaaa agatgctttc ttaatagatt caactaattt
    17941 tgaaaaactt gaagatggaa gttacatgta tgaaataaat tcaaagggta aaaacccaga
    18001 agtaagtcaa tatggtaaaa atataaaaat aaataaaaac tatcttaaag ttaaccctat
    18061 ttactcaaat ggcaaagaaa tatttaatct aatcgattat gacgataaga ctataaattt
    18121 attagttcct aaaaagttac aagtacatga aaatgagatt aaaaaagagt ttagagaatt
    18181 attttatttt gaaaaaatag aagtagaaaa tatgtacaat aaagagttaa atagagcgtt
    18241 aaacaaaaca aagaagtcag atttaaatgt taatataata tatgtagata ataatcaaag
    18301 ctattttact tataactccc ttgttatgga tgacaatagg aatctcattg atgacccaat
    18361 agcaatagtt gacatagata atattgatga ttctttttat ctttcttata tatctagatg
    18421 tgtatatttt aattctaaga aattagatgc ccttgcagat ataagtagca ttattgaagc
    18481 tcaaggtgta gaagcgcata tccaaagttt acatgctgtt tataatgagt atggtttaga
    18541 aataaataaa ctagaaaaat atttgaatag tgaaattttt actataataa taatagcaat
    18601 atcaaactta atgattacct acaatatagt agctagctac tatgaaagaa ataaatataa
    18661 gttatatatt aaaaaaatat ttggttattc aactacagct agaagtatgt tgttaatagt
    18721 ctcattaata ttaacaaaca ttattccaat aggcattata tcaacaagag tagatttaag
    18781 taataatatt atcttatttg gacttctaat attagttata gaagtaattg tatctattgt
    18841 attagacaag attatctcaa atagttcatt taataaaatt ataaaaggag aacattaaaa
    18901 agatgatttc attaataaat atatctaaaa aatttaaaga taaatctata atagacaaat
    18961 ttaacctaga aatttctaag ggcgagtttg tagcgataac aggaaatagt ggttcaggta
    19021 agacaacttt acttaatata atgggattat tagaaaaacc taattctggt gatattataa
    19081 taaataatat aaaaaatcca aatagtaaac agataagaat tttacaaagg gatttttatg
    19141 gctatctatt tcaaaattat gctttaattg agaatgaaaa tgttgaaaat aacttgaaaa
    19201 ttgctttaaa gtatcaaaaa aatatcaacc ataataaaaa aataaattac gcacttgagt
    19261 ctgtaggtct tagaaaatac aataaaaaaa agatatacga attgagtgga ggagaacaac
    19321 aaagggtagc attagcaaga gtaatattaa aagaatgtga agtaatattt gcagatgaac
    19381 ctacaggtaa tttagataaa aaaaatagag acatagtatt tgatatactt aaaagtctaa
    19441 ataagaatgg taaaactatc gtatttgtaa ctcatgattt agagttatcg gagcaggcag
    19501 atagagttat aaaattgtaa taatatcaac tataataaat ataagaaaga gattacagct
    19561 aaatcaagtt taataataat acgaatagaa tttaaacatt aagtaaatta gtagtttgta
    19621 aatataagta taatatgata tcataaaggc tcaaaagaaa ttttatataa taagaaatct
    19681 aaaaataaca aatggaggac atataaagat ggaaaattta ccaaattgcc cgaaatgtaa
    19741 ttcagaatat acttatgaag atggaactct tttagtttgt ccagaatgct ctcatgagtg
    19801 ggcattagga ttgggagctg aagaagattc aaatattatc aaagatgtaa atggaaatgt
    19861 attaaatgat ggagattctg ttacagtaat tagagacctt aaagtaaaag gaagttcatc
    19921 atctataaag attggaacaa aagtgaaaaa tatccgttta atccatgact catcagatgg
    19981 acatgatata gaatgtaaga tagatggttt tggagctatg aagctaaagt cttctgttgt
    20041 taaaaaagcg taatattata aataagctgt agtgtttatt gtttttcagt acagtataaa
    20101 accataagaa tctattaagt aataaaagtt tgtttattta tctttatatt ttcttatggt
    20161 tttattaaat ataaatttta ttgaacacca aaatattctc tcctctacaa ataagccaat
    20221 cttatttaaa ttaatatact ttgtactatt tatactgaaa ttgtaaattt aaatgctatg
    20281 ttatttaggt ttgtatagtt aatttatata tttctgattt tataaattgt atttattatt
    20341 atatcttgat tctaaaatca ttaaaaattt caacttctat aaagatttac aatttatcaa
    20401 atacattatg agtatataaa caatttatta ttacagtgct acatttaaaa taagtcttag
    20461 tataaaggta ttgttacaag tataaagaaa cttatgtatg ctattggaat aaataatacc
    20521 ttaaattata ataaagaata agaactgtta aataagggac ttgattatca tttagttata
    20581 gataatataa tattaaaaat aaagtttaag aggagaaaaa atatgataga tatacataaa
    20641 aatatatatg ataataagtt atttgaggag ctaaagattg actgtaagaa gtgctttgga
    20701 ctttgctgtg tagctcttta tttttctgct tcagatggat ttcctatcga taaggaatca
    20761 ggaaaaccct gtattaattt acaaccagat tttaaatgtt ctgtacataa tagtcttatg
    20821 aagcgaggtt ttaaagggtg tactgcatat gattgttttg gttcaggtca aaaagtagca
    20881 caagtaacat ataaggggat agactggatg caatcatcag aactaacaaa tcaaatgtct
    20941 gaagtgtttt taattatgag acaattacat gaaatgttat ggtatcttaa agaagcatct
    21001 gtattaaata tatcagatac aatcaaatca aaaattgatt taataattga agaaactgaa
    21061 aagataacta atatgagccc agaacagata attaatttgg atatcatatc acatagaata
    21121 aaggttaatt tattattatc acaagcgagt gagtctgtga tgggaaaggt taaatcattt
    21181 atcaagactt ctactcttaa aaacatgaaa aaattaagta aaaatataga tttaatagga
    21241 gcagacctta gaaaaataaa tctaatagga gcagatttaa gaggtagatt tctaatagca
    21301 gcaaatttaa gaaatacaga tttgagtggg gcaaatttaa taggagcaga cttaagagat
    21361 tgtgatatta gaggtgctaa tcttgaaaat agtatatttt taacacaatt acaagtaaat
    21421 actgcaaaag gagattctag tacgaagtta ccagcttcac taatacgccc taaatactgg
    21481 gaaaaataat taaattaata cataatttta caaaacatga acttttttga ctttaattca
    21541 tattatacat tagagattct ttacaagaat ttcttaatat aatataggga gagatataaa
    21601 aatgagttat caaaattata aatgtgaaag agattatgtg tatgatgatt ataaatacaa
    21661 taagtgcaac aagtgctata atgattatga ggaaatgaca catgttcatg aatattcaga
    21721 aagtgttaag ttagcagaag aatgtgagga tagacataac caccgtgcag caggggttac
    21781 tggtgaagct ataccaataa atggaggtac aaatcatgtt cataaaataa atgataatgt
    21841 agatttcctt gaccatttcc ataagatatg tgttacaaca gggccagcaa ttagaatacc
    21901 tggaactgat aaacacattc acttaatatg tggagaaact actgttaatg atggtcattg
    21961 tcataaattc ctttttacta ctcaaataga agcaccttta gtataagctg atgtgaatta
    22021 ttgtagtgaa tttgctagat tatagtataa taatatataa tagataatat ttaaacttaa
    22081 tgaggactat gatatttaac cttcgtagtc ctttctaagt tttgtataaa aaagtgttat
    22141 gcaattaaaa gtgatatagg gaggaaattt ttatgaaatc tggaataatt cttgaaatga
    22201 aacaaataaa ttcaacagaa tatgacgaaa tgttgcaagt ctgggaatca tcagtaagag
    22261 caacgcatga ttttttaaca gaaaaagata ttgaatcttt gataccatta gttgagattg
    22321 gacttaaaga agtagaaaat atagtttgta taaaagataa tgatataata aagggcttta
    22381 taggaataga taaagataaa attgagatgc tctttataga agataaatat agaggaaatg
    22441 gtattggtaa aaaattaata aaatatgcta tagataaata caatgtaaaa tatgttgatg
    22501 taaatgagca gaataaaaaa gctgtaggat tttatattca cttaggattt aaagtgtttg
    22561 ataggtctga aatagatgga caaggtaacc catttccaat actacatatg aaattaattt
    22621 aaagttatac ttctcattta ttcgcaaaaa tatttactta aatttttata caaataaaag
    22681 tcgtgacagt cttaggacac gactttttta ctacactatt aaattgaaat ttatctgttc
    22741 tatattatga ttattagatg tcgttttttt attttaacta tgtacttaaa taccaagtat
    22801 acccatacct atcaagtact tcagcagcgc catcattttg atgtggtggt gggtgtggta
    22861 aaaattcttg tacaagtgta ccaccttcgg caagttttac agatatttct tctatcgctt
    22921 ctcgagatgg tagaacaaca caaatcgcca tgccagaaat tacaacaggc ttgtctgtat
    22981 ccgcacccat tatacaacct tcgtattttg tgaaagtaac acttgcgtgc ataataggat
    23041 tgtttggatt gctgtctaat cgcgcaaata tagtttttcc tcctccgaaa gcctcagcat
    23101 aaaaattaaa tgctttttca caagtaccat taaatattaa atatggagtt agcatgacca
    23161 atatatcctc cttgatatag aataatttat agttgcacct gataatctaa attatgattt
    23221 agtaaattgt atcataggga aaccttgaag tatataattt tttattatta tattatacaa
    23281 atttattaat ttaaaaaaat gttatatgta cggaaggttt acaggataaa atataataaa
    23341 aagattaagg tgacattata aaaaatgtat attgacattg acgctacgta attgtatata
    23401 ctttgtctta aaggagatgg taaatatgaa tattatagaa attcgctcag ataaaatata
    23461 caagaagata atggatgcac caataaacaa aaaagaagat atatacagat atgaattgat
    23521 gaagcctttt gaatttaagt ggaagtgtat gaatgttcca atagttgcta gacagaaagg
    23581 tggatatgat gtaattatag caagtgaaat gttaggggtt ttatcgccta aggatattga
    23641 tgaaaaacaa aaaaagaata taaatgtgtt atctgctgat aaaatttggg ccacttgtaa
    23701 agaaaccata gaaaactcta taaatgcttt tataaaagaa gggtatgatt taaatattaa
    23761 ggactataaa tattcaatat tattggcgaa tccaaatagt ccttatacaa tattaagtga
    23821 tggatactgg ggtgatggtg ggattcctgg atatatattt ctatcattgg ttcctaatga
    23881 atatactatc aatagattac cagtattaat agcacatgaa tgtaatcaca atattagatt
    23941 tcagtttata gagtggaata ataatataac attagaagaa atgatgataa atgaaggtct
    24001 tgcagaaaat tttgcaacat ggatgtttgg agaggaaatg ttaggacctt gggtcagtag
    24061 aacagatatc gaaacattaa atacttatat aaagccaata ataaaaagtg ctttaaaaga
    24121 aactggattt caaaatataa catcttatct ttatggtgat gatatagcta aaatgcaagg
    24181 atattttcca gtagggttgc cttattgtgc aggatatgct tgtggatatt atatgattaa
    24241 gtattattta gaaaagacaa ataaatcaat aatcgaagcg actttattgc cttatagtga
    24301 gataatcgaa gcagtaaaag agttttggga ataaatttta taaattgcat aatttgaaat
    24361 aaattatgca attattttat ttttaagaaa aaataaattg acaataattt ataagaaata
    24421 tacaataata tatataaaga aatatttcaa tatttaaaag ttttaagatt tcatat
//
LOCUS       DAJMZY010000056        24469 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.056, whole genome shotgun sequence.
ACCESSION   DAJMZY010000056 DAJMZY010000000
VERSION     DAJMZY010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 24469)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24469)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24469
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.056"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            261..1082
                     /locus_tag="OE968_002181"
     CDS             261..1082
                     /locus_tag="OE968_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoxR family ATPase"
                     /protein_id="HCP7219459.1"
                     /translation="MIKKEISNFRGSSDYVVSPELMASVNVAIALEKPLLIKGEPGTG
                     KTMLAQAISNELKKDLVIWNIKSTTKAQEGLYVYDTVQRLYDSQFGGEGVDDISKYIK
                     YGKLGEAFSSNQQVILLIDEIDKADLEFPNDLLWELDKMEFYINETKETVRAKQRPIV
                     IITSNAEKELPDAFLRRCIFHYIEFPDRDMMEEIVKVHFDKVEEHLLEQVMTTFYWIR
                     SLKDIQKKPSTSELIDWIQALTLSGMPIEKIEKEVPFAGILLKNNEDIESMQRHL"
     gene            1103..2299
                     /locus_tag="OE968_002182"
     CDS             1103..2299
                     /locus_tag="OE968_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HCP7219460.1"
                     /translation="MFIEFFYLLRSRGLNVSLNEWMTLIEALDKGLCYSNFSNFYYLC
                     RMILIKSESDFDKFDAVFLEYFKGIEHQEEIPEEIMNWLKKPDIDLEEFERLEQNPNI
                     NLDKLRAKLEERIKEQDSPHNGGNYWIGTGGTSELGHSGKGQTGIRIGGNSTYGRAVL
                     EVAGERKYRDFRDDEVLNMRQFQVALKRLRQFSTRIDAPKTELDLDKTIEETCNNAGY
                     LKLFFEKPRKNTVKLLLLMDSGGSMRGYSTLCNTLFQSVSKSNHFKDVKIYYFHNCIY
                     DRLFTTPECWLSKSINTEWILKNIDKNYKVIIVGDASMSPSELLHIGGNYRGPYNYTP
                     GIEWLKRFKRKYSKIVWMNPELRDGWDSINYWYQTQRMIQSEFNMFPLTVKGLEKALK
                     NLMVSR"
     gene            2466..5864
                     /locus_tag="OE968_002183"
     CDS             2466..5864
                     /locus_tag="OE968_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HCP7219461.1"
                     /translation="MIIINYELIVKYNGDILRLEEELGVSVEILNSSYAIITSSNEED
                     VNILLTYPEIEFIEKPFILQTQDVQSFSSTGITGFKNRTGLTGKGTIIGIIDSGIDYT
                     LPVFRDSDGRSKILYYWDQSIQGNPPEGFREGTLYTNEDINNAIDGSMYIPISTTSLH
                     GTHVAGICATIASDARIIVVRVGNIQTDIFSRSTEFMRAIKFILDRALELRMPVTLNI
                     SYGSNEGSHRGTSLFEQYIDDMCLFWKNNIVVAAGNNADKGGHKRIRLQNNITEEVEF
                     IVGEGERILNINIWPDFVDDFSVHLVNPSNNQTQAISLTSGEIRNTLGETRITGYFYP
                     IAPYSLTRRVTLQLSSNTQITPGLWKIVFEPIDIVTGNVNIYLPTSEGLNRNTRFLIP
                     TQELTVTVPGTASRVITVGSFNSRTDIVSIFSGEGDTQLGVFKPDLLAPGEDIVSFLP
                     GGTSGALTGTSMATPHVTGVCSLFMEWGIVNGNDLFLYSQKLRALLLKGARRLSNQSY
                     PNNSSGFGFLNLSDIDLYTLSNINQDLETEDIGYRSINKSFKDEENSYKFIDGYNMQI
                     HNDLENEIYISKNASRQSGILSGIDIVHTPEFEEELAGLGMSQRFFKISDSLGVLSIN
                     NTDYNSIQRVLQLPSIIRTVSTTKMTLLGEINRGTFGGVVATEEMGVNFFKNNPNINI
                     TGRGTLISIADTGIDYLHPDFIYPDGTSKIVYLWDQTKEGTPPDGFYIGTEYTREDIN
                     RAIAENDPSLSQDEVGQGTMLSGICAGLGNVNSEYAGIAEDSELIIIKLGKIDDFYNS
                     AMLFAASQYAYKKAFELGRPLVINMSLGTSSLAGLTNRSNSEKAFFTRGLCITAGAGN
                     EGNTQTHTSGIIPYVGGSVEVELELNEDEEELSLELWLNRPDKADVIIVSPTGEESKS
                     VGISNYNKVTGLFDLEGTEYSITYIYPTTFSGQQFTNVTLKNAKRGVWKIRLVGVYII
                     TGRYNLYLPNRELLKSGTRFREVDPFYTINYPAIQDDLITIGAYNTINGSLWQSSSRG
                     PTIEDRLKPDIVAPGVNIIAAYPGNTYATITGTAAASAHAAGAAAMYFQYTFVDGRYP
                     NQAYVQKIKTFMQAGARKDSNTVYPNTNSGYGLLDVRGMFDVLR"
     gene            5874..7547
                     /locus_tag="OE968_002184"
     CDS             5874..7547
                     /locus_tag="OE968_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family peptidase"
                     /protein_id="HCP7219462.1"
                     /translation="MEKSYCIIYQGDIESALQENGINRYMVLNSQLAVIYVPLDFDET
                     ILNNIIQVAWWEESEPMSSLIEITNNVNNGETITTAAETDYIYENPYNDITGRGILLA
                     VIDSGIDYLHPDFINDDGTSKVLYLWDQEANTNPPPEGFIFGSEFTRSELNIAINRND
                     GSLSQDNIGTGTLVSGILVGNGRINSQYRGITTESDLIVVKLKSYTDTYYAGRINYSV
                     SDFLAAITYVTNIARTENKPLIINLTIGVKSSAVATTSILDTFNILSSAGVVVVSGAG
                     NQGNTDIHYSGRFSSVGEVQDVIIQDGDDYALDITLNTNGPDKVGAQIISPSGEVSHD
                     IRYSPDFYIYRGKFNLENTTYAMRFIYPYITSGKENLEIRLRDIKPGVWILRLTSELI
                     INGEYDIYLPNKNLIAPDTRFLDPDSVATITMYAASDDVITVGTFNNKTDSMWIGSSK
                     GPIRGRGIKPDIVASGVDIISTYKNGTYNTGTGTGVSSSIVTGVLALLMEYLEKQDNV
                     PRLSLFTQVLKTYLILGATKLEIYTYPNVSQGYGILNLKNTIQQIANTL"
     gene            7820..8014
                     /locus_tag="OE968_002185"
     CDS             7820..8014
                     /locus_tag="OE968_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3787 domain-containing protein"
                     /protein_id="HCP7219463.1"
                     /translation="MESKKARALKGKDNKRLKSSLLVGNESTAAWADVEKLKPHSKVS
                     IPSIKGVEEAKDWVDNGSKL"
     misc_binding    8183..8416
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            8493..9890
                     /gene="asnS"
                     /locus_tag="OE968_002186"
     CDS             8493..9890
                     /gene="asnS"
                     /locus_tag="OE968_002186"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HCP7219464.1"
                     /translation="MQKEFITVKELYREKEQYIGKTVKVAGWIRTSRVSKNFGFIELN
                     DGSFFKNMQIVFDEKVENFKEVGKLAISSSILVEGELVSTEGAKQPVEIHAKSIVVEG
                     ESDSSYPLQKKRHTLEYLRTIAHLRPRSNTFSAVFRVRSIAAYAIHKFFQERNFVYAH
                     SPIITGSDCEGAGEMFRITTMDLNDIPKTEDGKIDYTQDFFGKEANLTVSGQLNAEIM
                     ALSFRNVYTFGPTFRAENSYTGRHASEFWMIEPEIVFADLEDNMELAEDMIKYVISYV
                     LENAPEEMEFFNSFIDKGLLERLNKIVNSEFIRITYTKAVELLIESGHEFEYPVEWGC
                     DLQTEHERYITEQIYNCPVFVTDYPKDIKAFYMRMNEDGKTVRAMDLLVPGVGEIVGG
                     SQREEREDVLLDRINEMGLREEDYWWYLELRKFGTATHSGFGLGFERIIMYMTGMSNI
                     RDVIPFPRTPKNAEF"
     gene            complement(10063..11238)
                     /locus_tag="OE968_002187"
     CDS             complement(10063..11238)
                     /locus_tag="OE968_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HCP7219465.1"
                     /translation="MNLEKIKKFFGFPLDKKHKDNVEKELCNYLYHTGKIICIIIVIS
                     QIIMMISISAREGGPFVTPRRQWYFYMYVTLFCVSSVFMFVFSYLWNKKKDCCTFYIN
                     LWIIYVTFFCLWGCVITLLDQLGGNDLSVFSYIMLAAAAFSVLKFGESVIVFGGCFLF
                     LNLFLPGIQTIPGNEFSNIVNTFFITSLAIFVSTMLYRNRVFTYYDKLLISQQYEEIS
                     HINNLLNDKVMTDDLTKMNNRRYLEDILQKKLISHANQEPITGMMIDIDYFKQFNDNY
                     GHQKGDYCLQNIAKVILDFTSSENEHAIRYGGEEFFICIFNCNEADAKLKSECLRKII
                     ESCNFERDDVPLKCVTVSIGVYTKKIGKTITLNEFISNCDKALYTAKEQGRNCVAFY"
     gene            11657..13021
                     /locus_tag="OE968_002188"
     CDS             11657..13021
                     /locus_tag="OE968_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HCP7219466.1"
                     /translation="MGEKKINNMNYSHNNYSKKTGEPTRKIKNSHITLKSKEEKICSS
                     CNKENNTKDNYCKFCGNELYEIASLRPLETKLDLKSKIKELSYHANKRGVFLTTFTTI
                     FILFIIALIFKAIITIQFNDISYLVNPAHIILALNLGQISVSMSTMMGSGFINANIGL
                     LILLIIPILVLLISNLIFMRKRCRDSKTVLANSLGVGIFYGLVLAILSIFTNVKTSSH
                     SMLEYGYALEYSYEFFSVLLNGFVLGFICTYITTYKKSYEKENMYLSLFSNSIRTFIL
                     GYVLVLVILLVLTISDSSYLNELDMSSYSNGLNLFTILPQIASYMWAFANGISVTIIN
                     STVSMFTLSSSSLFGDTKLMFYAMGALSMLILLLNGYKLRFKYNTDSIRPIIVFSIYY
                     AFLMGILALFSTFILDSNINFFNTTNYGTTLIMQFKVLQAIVISFVYSFVISLIGYKL
                     NSAD"
     gene            13043..13534
                     /locus_tag="OE968_002189"
     CDS             13043..13534
                     /locus_tag="OE968_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HCP7219467.1"
                     /translation="MEGNTNNKVDDKFSKVKKKFGSGKFKVELYKEKSKLNREIDDIQ
                     EKKAKIFLEMGILTYQKIREDSINDNSFDKFCDELLELDKLIYEKNMEINEMEMAESN
                     VTCECGYVGNVNDKYCAECGKKFELENECDDFIICGYCESEIDTEAEFCPCCGRKIIM
                     DLE"
     gene            13806..14477
                     /locus_tag="OE968_002190"
     CDS             13806..14477
                     /locus_tag="OE968_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HCP7219468.1"
                     /translation="MLDKVKGRLIVSCQALENEPLHSPFIMGRMAKAAMEGGAVGIRA
                     QGVEDIIEIKKVTGLPVIGIIKRNYEDSDIYITPTKKEVDELLTTGCEMIALDATNRV
                     RPNNEDLKELIKYIKENGVLVMADISNYDEAIKAQEYGVDCVSTTLSGYTPYTKTLEG
                     PDFVLMKRLVKDLEIPVIAEGKVNTPQDLKKVFELGVHSSVVGSAITRPQLITEKFVK
                     AIEIN"
     gene            14562..15428
                     /locus_tag="OE968_002191"
     CDS             14562..15428
                     /locus_tag="OE968_002191"
                     /EC_number="4.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003452648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate lyase"
                     /protein_id="HCP7219469.1"
                     /translation="MKGIYSALLVSFDKEGNINEKGLRQIIRHNIDVCKVDGLYVGGS
                     TGENFMLSTDEKKRIFEIAKDEVKEEIKLIAQVGSVNLKEAVELAKFTTDLGYDAISA
                     VTPFYYKFDFEEIKHYYNTIINSVDNRLIIYSIPFLTGVDMSLDQFGELFENEKIIGV
                     KFTAADFYLLERMRKTFPNKLIFAGFDEMMLPATVLGVDGAIGSTFNVNGVRARQIFE
                     LTKNEKISEALEVQHVTNDLITDILGNGLYQTIKLLLEEQGVEAGYCRQPMKEATDEM
                     KSRAKEIYRKYF"
     gene            15461..16963
                     /locus_tag="OE968_002192"
     CDS             15461..16963
                     /locus_tag="OE968_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003462875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter"
                     /protein_id="HCP7219470.1"
                     /translation="MVGFTWIDFAILVVYLLAVLFAGLLFSKKEMKGKEFFKGDGTIP
                     WWVTSVSIFATLLSPISFLSLAGNSYGGTWILWFAQLGMFIAIPLTIKFFLPLYSRLE
                     IDTAYEYLEMRYESKGLRVLGALMFIIYQIGRMSIIMYLPSIVLAGLTGIPVNVLIIV
                     MGVIAIIYSYTGGLKAVLWTDFIQGMVLIVGVTGTLFYLIASINGGFGTVMDTLTTGH
                     KFLASNEVMFDKNILSTSAFIIFVGAGLNTFSSYVSSQDIVQRFTTTTDIKQLNKMTY
                     GNGVLSMGLATVFYLIGTCLFIYYTQNPDLAQTVQQDQVFASYIAYELPVGITGILLA
                     AIYAASQSTLSTGLNSVATSWTLDIQTIITKDISMEKQTKIAQYISLGVGILSIAVAI
                     VLANGEIKSAYEWFNSFMGLVLGVLAGIFVLGAFCKKATKMGAYVGFIVSAILVVYLK
                     YRMPEVTSWAYSLITITTSVVVGTIVSAIEAKVKAKVSLPKAETTVYYEK"
     gene            17093..17545
                     /locus_tag="OE968_002193"
     CDS             17093..17545
                     /locus_tag="OE968_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HCP7219471.1"
                     /translation="MIFGNINHSKTYSTLHEDLLRCFEYAKDNSLIDYEKGTYTIDGD
                     DIFVNIVEYKTCEKEDRFWEAHKKYIDVHLMLDGCERIDINFIENLEQKIYEEKGDFL
                     PLDGKNNGYMELRKGDFLVCYPEDAHMTGIKVLEKENIKKAIFKVLVR"
     gene            17705..18508
                     /locus_tag="OE968_002194"
     CDS             17705..18508
                     /locus_tag="OE968_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219472.1"
                     /translation="MENIDVFLLIGQSNARGLGNPKESIIPNENCFEYLSTDEIINMR
                     CELETSEGDGTIAPAFSNEWNKLTGNKVCFIHNAKDGSRIKNWNHDNNWFLNDTIEKF
                     NTGCTTLSKHYNIENKYVIWIQGESDAKYGSDVLYYKESLKKIAYRLKEECMIDKMFV
                     SLTGYWLGEDEYFIRTRRIAAAQESACSECDILCVGSKIAMQFHDRGLTIDDVHYTQE
                     GLNMLGEDLCKNIYKYHITKEKSVLSDTIDLSEARKYICELEKISKRFV"
     gene            18566..19453
                     /locus_tag="OE968_002195"
     CDS             18566..19453
                     /locus_tag="OE968_002195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HCP7219473.1"
                     /translation="MKNYVCIDVGGTSIKYGFIREDGFIIDKSSLDTEAKEKGGEGIL
                     AKIKDIVKKYIEENEISGICISTAGMVDPVEGKILFALEELIPNYKDMQLKKEVEKEF
                     NIKCEVENDVNCAGLGEMWLGAGRGATSSICLTIGTGIGGCIIINNKLINGFSNSAGE
                     VGYMNVNGSSFQELASTSSLIKKVAKIKNLNENDLNGKIIFDLAKNNDEDCLKELDNM
                     IKSLAVGIANICYVINPEVVILGGGIMAQEKFLKPKIDKALKEVLIERVYKNTNIEFA
                     KRQNDAGMLGALYNFLNKI"
     gene            19472..20320
                     /locus_tag="OE968_002196"
     CDS             19472..20320
                     /locus_tag="OE968_002196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HCP7219474.1"
                     /translation="MSILEQLESPTFKVTKSDKLLIAYIKENIDDVFYKPISQIAKES
                     NIGEATITRFVKKMNFNGLQDFKVTLAQEISTINKKNIINKNIQNDEPALDTAKKLLS
                     SNVTTLENTVEIINSKDVHDCARLIINAKKVYFIGIGYSGIIAQDSNYKFMRIGLNCV
                     SFDSSHTMIMMSSIMEEGDLIIAISHSGETEEIIKTVKLARANNAKIISITENKNSEL
                     KDISDVHLSYVSGETVLETGSISSKLAQFFIIDLVYTQVVKELSNEAIERKIKTTNAI
                     KLFKNE"
     gene            20383..21072
                     /locus_tag="OE968_002197"
     CDS             20383..21072
                     /locus_tag="OE968_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HCP7219475.1"
                     /translation="MSKLKDYNIDKVIIFNNLSTKTKNQLKEKVKLKRLQKKEILFYE
                     KDSLDSVYILLEGKVSIFKISENGERKVIFILNSGEVINDITLDASKNSTVGCEAFEN
                     SIVAYYSIEEFLEIMQNDFQLTKDIISYMERRIRRLYRQLKNSISIKVDKKLAAKLYR
                     LSREFGVCCGEWTLLNVNITVTYLADMLGCKRETVSRMIKVLQKEELIKIDNKGFYVK
                     ETELSRYFKNN"
     gene            complement(21402..22592)
                     /locus_tag="OE968_002198"
     CDS             complement(21402..22592)
                     /locus_tag="OE968_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009271880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HCP7219476.1"
                     /translation="MSNVKRKDSKNRNLRNGESQRKDGRYVYKYTDIYGKPQFIYAWK
                     LVPTDKTPAGKRDDISLREKEAQIKKDLDDGIDTAGGKMTVCQLYDKKNSQRKNIKRA
                     TEKGRQYLMNALKNDPLGMRAIDTVKQSDAKEWAIRMSERGYAYKTIDNYKRSLKASF
                     YMAIQDDCIRKNPFEFKLSDVLEDDTEPKVILTPEQEERLLAFMETDKIYSKYYDEVV
                     LLLETGLRISEFCGLTTHIDMQNRILNIDHQLLRDSEIGYYIDTPKTKNGKRKIPLTE
                     RAYQALQRILKNRVKAQPLVVGGYSNFLFLNREGLPKVAGNYVGMVRGLIKKYNKYHK
                     DKLPNITPHSFRHTYCTNMANKGMNPNTLQYLMGHANITMTLGYYAHGTFQSAKAELE
                     RLAC"
     gene            complement(22670..22873)
                     /locus_tag="OE968_002199"
     CDS             complement(22670..22873)
                     /locus_tag="OE968_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HCP7219477.1"
                     /translation="MNNTDVPIWEKYTLTIEEASKYFRIGEKKLRKLAEENIDAGWVI
                     VNGNRIQIKRKQFEKIIDTLDEI"
     gene            complement(23255..23503)
                     /locus_tag="OE968_002200"
     CDS             complement(23255..23503)
                     /locus_tag="OE968_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004613734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCP7219478.1"
                     /translation="MKHTFKKPSYYLLSQAMDGDEKAIEKVLAFYDPYISKCCLRPLY
                     DEYGNVYIVVDMELKGLIREALIKMILGFDIALEIEEE"
     gene            complement(23507..23926)
                     /locus_tag="OE968_002201"
     CDS             complement(23507..23926)
                     /locus_tag="OE968_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005361151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HCP7219479.1"
                     /translation="MKPSDFQKTVQCRFESCLKKVVRHVVKDYQQGLKRRKEKEISFC
                     ELPEIMVENLAVWDDYETDYTIFNVCGNDIRVYDDELAEALKQLSERNRETLLMYYFL
                     EMNNEEIAKKQNISRSGVFQNRHNSLALMRKLLKEKR"
BASE COUNT         9188 a         2924 c         4386 g         7971 t
ORIGIN      
        1 aaaagtggtg cctttgatta aactaagttt ttataattta aattttgtac aataagctat
       61 cttttattat tctttaaaat atatatttca tttaattatg acaaataaag ataaaaatta
      121 aatattttag aggtgatttt atttagatat agaattttag aataatacta tacaaatgta
      181 ttgtattatt atttttatat caaaaatagt aataaagtct atatacattt agaaaatact
      241 gtttaaaagg agtaggattt atgataaaaa aagagatatc taactttaga ggaagtagtg
      301 attatgtagt atcaccagaa ttgatggcat cagttaatgt tgctattgct cttgaaaagc
      361 cacttttgat taagggcgaa cctggaacag gtaaaactat gctagcacaa gcaatttcaa
      421 atgaattaaa aaaagattta gtaatttgga atataaaatc aactacaaaa gcacaagaag
      481 ggctttatgt atatgatact gttcaaagac tttatgatag ccaatttgga ggagaaggtg
      541 tagatgatat tagcaagtac ataaaatatg gtaaactagg agaggccttt agctcaaatc
      601 aacaagtaat tcttttaata gatgaaatag ataaggcgga tttagaattt ccaaatgact
      661 tgctttggga attggataaa atggagtttt acataaatga gacaaaagaa actgtaagag
      721 ctaaacaaag accaatagtt attataactt caaatgcgga aaaagaactt ccagatgctt
      781 ttttaagaag atgcatattt cattatatag aatttcctga tagagacatg atggaagaaa
      841 tagttaaagt acattttgat aaagtagaag aacacctatt ggaacaagta atgactactt
      901 tttattggat tagaagttta aaggacatac aaaaaaagcc tagtacatca gagttaatag
      961 actggataca agcattaact ttgagtggaa tgcctattga aaaaatagaa aaagaagttc
     1021 cttttgcagg aatactactt aagaataatg aggatattga atctatgcaa agacacttat
     1081 agttaatagg agctggataa ttatgtttat tgaatttttt tatttattga ggtcaagagg
     1141 attaaatgta tctttaaatg aatggatgac tttaattgaa gcattggata aaggactgtg
     1201 ctattcaaac ttttcaaatt tttactatct ttgcaggatg attttaataa aaagtgaaag
     1261 tgattttgat aagtttgatg cagtgttttt ggagtatttt aaaggtatag aacaccaaga
     1321 agaaattcca gaagagatta tgaattggct taaaaaacca gatatagatt tagaagagtt
     1381 tgaaagatta gaacaaaatc caaatataaa tcttgataaa ttaagagcta aattggagga
     1441 acgaataaaa gaacaagatt ctcctcataa tggtggtaat tattggatag gcacaggagg
     1501 cacttcagag ttaggacatt caggaaaagg gcaaactggt atacgtatag gtggaaattc
     1561 tacttatggt agagctgttc ttgaagttgc aggagaaaga aaatatagag attttagaga
     1621 tgatgaagtt ttaaatatgc gtcaatttca agttgcacta aagagacttc gtcaattttc
     1681 tactagaata gatgctccaa agacagagct tgatttggat aagactattg aagagacttg
     1741 taataatgca ggatatttaa agttattttt tgagaagcca agaaaaaata cagtgaagct
     1801 tttattgctt atggattcag gtggttcaat gagagggtat agcactttat gtaatacatt
     1861 atttcagtct gtaagtaaat caaatcattt taaagatgta aagatatatt atttccataa
     1921 ctgtatttat gatagattat ttacaacacc tgaatgttgg ttaagtaaat ctattaatac
     1981 tgaatggata ttaaaaaata tagataaaaa ctataaagtt ataattgttg gagatgcttc
     2041 tatgtcgcct tctgagttgc ttcatattgg tggtaactat cgtggtccat ataattacac
     2101 acctggtata gagtggctta aaaggtttaa gagaaagtac agtaaaattg tatggatgaa
     2161 tccagaactt agagatggat gggattcaat taattattgg tatcaaactc aaagaatgat
     2221 acaaagtgaa tttaatatgt ttccattgac tgtaaaaggt cttgagaaag cattgaaaaa
     2281 tttaatggtt tcaagataaa gtaaatataa atgatggtat gatttattca aaattgtacc
     2341 atcattattt atttttttaa tatacctatt ataaattgta taactgaaac ttaaaaaatt
     2401 atatagtcta atacatttta gactcacaca aaacatatac attaataata attttagaag
     2461 tcgaggtgat tataataaat tatgaattaa ttgtaaaata caatggagat atattgaggt
     2521 tagaagaaga attaggtgta tcagtagaga tacttaattc atcatatgca ataataacat
     2581 caagtaatga agaagatgta aatatacttt taacttatcc agaaattgaa tttatagaaa
     2641 agccttttat attacagact caggatgtgc aaagtttttc aagtacagga ataacaggat
     2701 ttaaaaatag aactggttta actggaaaag gaactataat tggtataatt gattcgggaa
     2761 tagattatac tctacctgtg tttagagata gtgatggaag gtctaagata ttatattatt
     2821 gggaccaatc tattcaagga aatccaccag aaggttttag agaaggaaca ttatatacta
     2881 atgaagatat aaataatgca atagatggaa gtatgtatat acctatttca acaactagct
     2941 tacatgggac acatgttgca ggtatttgtg caactattgc aagtgatgcc agaataatag
     3001 tggttagagt tggaaatata caaaccgata ttttttcgag aagtacagag tttatgaggg
     3061 caattaaatt tattttagat agggcattag aattaagaat gcctgttaca ttaaatataa
     3121 gttatggaag taatgaaggt tcacatagag gaacatcttt atttgaacaa tatatagatg
     3181 atatgtgttt attttggaaa aacaatatag ttgtagcagc tggaaataat gcagataaag
     3241 gaggtcataa aaggattagg cttcaaaata atattacaga agaagttgag tttatagttg
     3301 gggaaggaga gcgtatatta aacataaata tatggccaga ttttgttgat gattttagtg
     3361 tacatttggt aaacccatca aataatcaaa cacaagcaat ctctctaact tcaggtgaga
     3421 taaggaatac tttgggtgaa actagaataa ctggttattt ttaccctata gcaccgtatt
     3481 ctctcacaag aagagttact ctacaattaa gttcaaatac acagataact cctgggttat
     3541 ggaaaattgt atttgaacca atagatatag taactggtaa tgtaaatata tatttgccaa
     3601 cttctgaagg tctaaataga aatactagat ttctgattcc tactcaagag cttactgtaa
     3661 cagttcctgg aacagcaagt agagttataa cagtaggtag ttttaattca agaacagata
     3721 tagtatctat attttctggt gaaggagata cacaattagg tgtttttaaa cctgatttat
     3781 tagctccagg tgaagatata gtatcttttt taccaggagg tacaagtgga gcattaactg
     3841 gaactagcat ggctacacct catgttacag gggtttgttc attgtttatg gaatggggaa
     3901 ttgtaaatgg aaatgattta tttttgtatt cacagaaatt aagggcatta cttctaaagg
     3961 gagcaaggag attaagtaat caatcttatc caaataattc atcaggattt ggttttttaa
     4021 atttatcaga tatagatttg tacactctat ctaatataaa tcaagattta gaaacagagg
     4081 atattggata tagaagtatt aataagtcat ttaaagatga ggaaaatagt tataagttta
     4141 tagatggtta taatatgcaa atacataatg acttagagaa tgaaatttat ataagtaaaa
     4201 atgcaagtag acaatcagga atactatcag gaatagatat agtccatact cctgaatttg
     4261 aagaagaact agctgggtta ggtatgagtc aaaggttttt taagataagt gattcattag
     4321 gtgtactatc tataaataat acagactata atagcataca acgagttttg caacttcctt
     4381 caatcataag aactgtatcg actacaaaga tgacattact tggagaaatt aatcgaggta
     4441 cttttggagg tgtagttgca acagaagaaa tgggcgtaaa tttctttaaa aataatccta
     4501 atattaatat aacaggaaga gggactctaa tatcaattgc agatacagga atagactatc
     4561 tacacccaga ttttatttat ccagatggca cttcaaaaat agtatattta tgggaccaaa
     4621 caaaagaagg aactcctcct gatggttttt atattgggac agaatataca cgagaagata
     4681 taaatcgagc tatcgcagaa aatgacccta gtctatctca ggatgaagtt ggtcaaggaa
     4741 ctatgttgag tgggatatgt gcagggcttg gaaatgtaaa tagtgaatat gcaggtatag
     4801 cagaagattc tgagctaata ataataaaac tcggcaagat agatgatttt tataatagtg
     4861 caatgctgtt tgctgcatct cagtatgcat ataaaaaagc ttttgaactt ggaagaccat
     4921 tagttataaa tatgtcttta ggtaccagta gcctagcagg tttaaccaat aggagtaata
     4981 gtgaaaaagc gttctttact agagggttat gtataacggc aggagcagga aatgagggca
     5041 atacacagac acatacatct ggaataatac catatgttgg aggttctgtt gaagttgaat
     5101 tagagttaaa tgaagatgag gaagaattat cattagaact ttggttaaat agaccagata
     5161 aagctgatgt aataatagta tctcccactg gtgaagaaag taaaagtgtt ggaatttcaa
     5221 attataataa agtaacaggt ttatttgatt tagaggggac tgaatattct ataacatata
     5281 tatacccaac aactttttct ggacagcaat ttactaatgt tactttaaag aatgcaaaaa
     5341 gaggtgtatg gaagattcga ttagtaggag tttatattat aacaggaaga tataacttat
     5401 accttccaaa tagagaactt ttaaaaagtg gaactagatt tagagaggta gacccttttt
     5461 acactataaa ttatcctgcg attcaagatg atttaataac cataggagcc tacaatacta
     5521 ttaatggtag tttatggcaa agttcatcaa gagggccaac tattgaagac aggttaaaac
     5581 cagatatagt agcaccaggt gttaatataa tagctgctta tcctgggaac acgtatgcaa
     5641 ctataactgg tacagcagca gcaagtgcac atgcagctgg tgctgctgca atgtattttc
     5701 aatatacttt tgttgacggt agatatccaa accaagcata tgtgcaaaaa ataaaaactt
     5761 ttatgcaagc tggtgctaga aaagattcaa acacagtata tccaaataca aattctggat
     5821 atgggctctt ggatgttaga ggaatgtttg atgttttaag ataggaggga tttatggaaa
     5881 aatcttattg tataatttat caaggtgata tagaatctgc cctacaagaa aatggaataa
     5941 ataggtatat ggttttaaat agtcagcttg cagtaatata tgtaccttta gattttgatg
     6001 aaactatttt aaataatata atacaagttg cttggtggga agaatctgaa ccaatgagca
     6061 gtctaattga aataactaat aatgtaaata atggagaaac cattacaaca gcagctgaaa
     6121 ctgattatat ttatgaaaat ccatataatg atataacagg gagaggaatt ttattagcag
     6181 ttatagattc tgggatagat tatttgcatc ctgattttat aaatgatgat ggaactagta
     6241 aagttttata tttatgggac caagaagcaa atacaaatcc acctccagaa ggttttattt
     6301 ttggaagtga atttacaaga agtgagttaa atatagccat aaatagaaat gatgggagtt
     6361 tgagtcaaga taatataggt actggaactt tagtttctgg tatattagtt ggaaatggaa
     6421 ggataaattc tcagtacaga ggtattacta cagaatcaga cttaatagta gttaaattaa
     6481 aatcatatac agatacttat tatgctggaa ggataaatta cagtgtttca gattttttag
     6541 cagctataac gtatgttact aacatagcaa gaacagaaaa taaaccactg ataataaatt
     6601 tgactattgg agttaagtca agtgctgtag caactacttc aatactagat acttttaata
     6661 tattgagtag tgctggtgtg gtagtagtga gtggtgcagg aaatcaaggg aatacagata
     6721 ttcattattc tggcagattt agcagtgtgg gagaagttca agatgtaata atacaagatg
     6781 gagatgacta tgctcttgat ataacactaa atacgaatgg tccagataaa gtgggagcac
     6841 agataatatc tccttcaggt gaagttagtc atgatataag gtattctcca gacttttata
     6901 tatatagagg aaaatttaac ttagaaaata ctacttatgc aatgagattt atttatccat
     6961 atattacctc tggaaaagaa aatttggaga taagattaag agatataaaa cctggagtat
     7021 ggattttaag attgacttca gaacttataa taaatggaga atatgacata tacttgccaa
     7081 ataaaaattt gatagctcca gacacaaggt ttttagaccc tgattcagta gctactataa
     7141 ctatgtatgc tgctagtgat gatgtaatta cagttggtac atttaacaat aagactgata
     7201 gtatgtggat tggttcttcg aaaggaccaa ttagaggaag aggaattaag ccagatatag
     7261 tagcttcagg tgtagatata atatccacat ataaaaatgg aacatataat acaggaacag
     7321 gaacaggagt gagcagttct atagtcacag gtgttttagc cttattgatg gaatacttag
     7381 aaaaacagga taatgtaccg agattatcat tgtttacaca agttttaaaa acatatttaa
     7441 tattgggtgc tacaaaactt gagatatata catatccaaa tgtatcgcag ggatatggga
     7501 ttttaaattt aaaaaatacg attcaacaga tagcaaatac tctatagata agaacctatg
     7561 taaaattata attgattatt agtttaattg tatcaaatac tttagataga gtagaaaaat
     7621 agcataaaaa ataaatatga aaattaaaaa acagttttat attttgaata cacaaagtaa
     7681 atattttgta tataaatagg tataaattaa gtattgaaaa gatatgatgt taatttaaaa
     7741 ataattataa tttagactta tgaattttat ttgtaaaatt gctaaaacta ttacaaaata
     7801 aataatagag gtgatagttt tggaaagtaa aaaggcaaga gcattaaaag gtaaagataa
     7861 taaaagactt aaaagttcac ttttagttgg aaatgagtcg acagcagcat gggctgatgt
     7921 tgaaaaatta aaacctcata gtaaagtttc aataccttca attaagggtg tcgaagaagc
     7981 aaaagactgg gttgacaatg gaagtaaatt ataaaatttt ggaaattgaa gtaataaaga
     8041 agtaatgaag ataagtattt attatcatta tgtaaggtag aattattata ttttaaataa
     8101 caatcagtat caattatata aatttattga ctaaaaattt ataaattggt ataattttgt
     8161 taattagcag aaataataaa agataaatac tgtgaagaga agagtagata taaaatgtag
     8221 ttctagcgag ttgaggatgg tgaaagctca atacgaggtt tatattgaag aacatcttgg
     8281 agtttctaat cgaaagctta tttagtaagt agacttagac ggaaggcacc gttataggct
     8341 ttaagcattg cttaactaag aggtcattat gacaactagg gtggtaccgc gagagtaata
     8401 gtctttcgtc cctttatata gggatgaagg gcttttttta ttgaaattat atttaaaaga
     8461 aattaataac aattatacta ggaggattta aaatgcaaaa ggaatttata acagtaaaag
     8521 aattgtacag agaaaaagaa cagtacatag ggaagactgt aaaagtagct ggatggataa
     8581 gaacatctag agtatctaaa aattttggat ttatagagct aaatgatgga agcttcttta
     8641 aaaatatgca gatagtattt gatgagaaag tagaaaattt taaagaggta ggaaaattag
     8701 caataagctc atctatactt gtagagggag agttagtatc tacagaaggg gctaaacaac
     8761 cagtcgaaat acatgcaaaa agcatagttg tagaagggga atcagatagt tcatatccac
     8821 tacaaaagaa gagacatacg cttgaatatt taagaacgat agcacattta agaccaagaa
     8881 gtaatacttt ttcagctgta tttagagtaa gatcaatagc tgcctatgca atacacaaat
     8941 tcttccaaga aagaaacttt gtatatgcac attctccaat cataacaggt agtgactgtg
     9001 aaggtgcagg agagatgttt agaataacaa ctatggattt aaatgatatt ccaaaaactg
     9061 aagatggcaa aatagactat actcaagatt tctttggaaa agaggctaat ttaacagtta
     9121 gtggtcaatt aaatgccgag ataatggcac tttcttttag aaacgtttat acttttggac
     9181 ctacatttag agctgaaaac tcttatacag gaagacatgc ttcagaattt tggatgatag
     9241 agccagaaat agtttttgca gaccttgaag ataacatgga acttgcagaa gatatgataa
     9301 aatatgttat aagctatgta ttagaaaatg ctcctgaaga aatggaattt tttaatagtt
     9361 ttatagataa aggattgtta gaaaggttaa ataagatagt aaactctgag tttattagaa
     9421 taacgtatac taaagcagtg gaattattaa ttgaatctgg gcatgaattt gagtatcctg
     9481 ttgagtgggg atgtgacctt caaactgagc atgaaagata tataacggag caaatatata
     9541 attgtccagt gtttgttaca gattatccaa aagatataaa agctttctat atgagaatga
     9601 atgaagatgg taaaactgtt agagcaatgg atttactagt tcctggagtt ggagaaatcg
     9661 taggaggttc tcaaagagaa gaaagagaag atgtattgtt agatagaatt aatgaaatgg
     9721 gattaagaga agaagattat tggtggtatt tagaacttag aaagtttggt actgctactc
     9781 actctggatt tggtcttgga tttgaaagaa taattatgta tatgacaggt atgtctaaca
     9841 taagagacgt tatacctttc ccaagaactc ctaaaaatgc tgaattttaa taattatata
     9901 taataaaact tatataactt taagtataaa cactaaaatg acttgcatat ttatctattt
     9961 tagagatatg caagttattt ttattgtact ataaatatat aatttgatta cttttatttt
    10021 gcgatataat acttataggt ttatgtaata gtatgtaacc ttttaataaa atgcaacaca
    10081 attacgtccc tgttcttttg cagtatatag agccttatca caattactta taaactcatt
    10141 taatgttatt gtctttccaa ttttctttgt ataaactcca atactaacag ttacacattt
    10201 taaaggaaca tcatcacgct caaaattgca ggactctata atttttcgta aacattctga
    10261 tttaagttta gcatctgcct cattacagtt aaaaatacat ataaaaaatt cctcaccacc
    10321 atatcgtata gcatgttcat tttcagaact tgtaaaatct aaaattactt tggcaatatt
    10381 ttgtagacaa tagtctccct tttgatgtcc ataattatca ttaaattgtt taaaataatc
    10441 tatatctatc atcattccag ttataggttc ttgatttgca tggctgatta attttttttg
    10501 tagaatatct tcaaggtatc tacggttgtt cattttagta aggtcatctg tcataacttt
    10561 gtcgttaagt aaattattta tatgagatat ttcttcatat tgttgactaa ttaaaagttt
    10621 atcatagtaa gtaaatacac gatttctata tagcattgta gaaacaaaaa tggcaaggga
    10681 tgttataaaa aatgtgttga caatattact aaactcattg cctggtatag tttgaatccc
    10741 aggtaagaat aaattaagaa acaaaaagca tcctccaaaa actattactg attctccaaa
    10801 ttttaatact gagaaagctg cagctgctaa cataatataa ctaaatacac ttaggtcatt
    10861 tccacctaac tggtcaagta gagtaattac acaaccccat aggcagaaaa aagtcacata
    10921 aattatccat aaatttatat aaaacgtaca gcaatccttt tttttattcc aaaggtaaga
    10981 aaatacaaac ataaagacag aagatacaca aaatagtgtt acatacatat aaaaatacca
    11041 ttggcgtctt ggtgtgacaa aagggcctcc ttctctagct gagattgata tcatcataat
    11101 tatttgagat attactatta ttatgcaaat gattttaccc gtatgataaa gataattgca
    11161 gagttctttc tcaacattgt ctttgtgttt tttgtctaga ggaaatccaa aaaatttttt
    11221 tattttttct aagttcatat aagcctccat taaaaataaa gcataaaaat aagtattcct
    11281 ttctatcatt agatatttgg aatacttcgt ttatgattta attatatcaa aatatattgt
    11341 gtgtaacaat ctaaaattgt gatagataaa atttattaga taatgtcgag taactttatt
    11401 gattaatact ttattataat taagatttac agatagttta ctactgaaaa taaagaatag
    11461 aataaattta aattaagcat aataaaatat aaataataaa gttcgcatta acaaactatt
    11521 taaatatcaa gacctgttaa aaaacaacag caataaacaa ataaaataga taaatatatc
    11581 caattaaggt ataattaagt tttatatgat atagttatat ttgataattt acaatagtaa
    11641 aacttggagg gaaaaaatgg gtgaaaagaa aataaataat atgaattatt cacataataa
    11701 ttattccaaa aagacaggtg aaccaactag aaaaataaaa aatagccata tcactcttaa
    11761 aagtaaagaa gaaaaaattt gttctagttg caataaagaa aataatacta aggataatta
    11821 ctgtaaattt tgtggaaatg aactttatga aatagcatca ttaagaccac ttgaaacaaa
    11881 actagacttg aaatctaaaa taaaagagct ttcatatcat gcaaataaaa gaggtgtatt
    11941 tttaacaaca tttacaacca tatttatatt gtttattatt gcattgatat ttaaagctat
    12001 tataactatt caatttaatg atattagtta tttagtaaat ccagcacata taatcctagc
    12061 tctcaacttg ggtcaaatta gtgtatctat gtctaccatg atgggttctg ggtttataaa
    12121 tgccaatata ggtttgttga tattacttat aatccctatt ttggtattat taatatcaaa
    12181 cctaattttt atgagaaaaa gatgtagaga ttcaaaaact gtattagcaa attctctagg
    12241 agttggaatt ttttatggat tagttttagc tattttatct atttttacta atgtaaaaac
    12301 tagttcacat agtatgttag aatatggata tgcattagaa tatagttatg aattttttag
    12361 tgttctttta aatggattcg tattagggtt tatatgtaca tacataacta cttataaaaa
    12421 aagttatgaa aaagaaaata tgtatttatc tcttttttca aattctataa gaacattcat
    12481 attaggttat gttttagtat tagtaatact attggtacta actatatctg atagtagtta
    12541 cttaaatgaa ctagatatga gtagttattc aaatggatta aatttattta ctatactccc
    12601 acaaatagct agttatatgt gggcttttgc aaatggaatt tcagtaacca taataaactc
    12661 aacagtatca atgtttactt taagttcttc atctttattt ggagatacta aattaatgtt
    12721 ttatgcaatg ggagcattgt ctatgttaat attattatta aatggataca agctaagatt
    12781 taagtataat acagatagta taagacctat aatagtattt agtatatatt atgcattttt
    12841 gatgggaata ttggccttat ttagtacatt tatactagat agtaatatta atttctttaa
    12901 tacaactaat tatggaacaa ctttaataat gcaatttaaa gtcttacaag ctattgtaat
    12961 ttcatttgta tatagttttg tgatatcttt aataggatat aagctaaatt cagctgatta
    13021 aatatgattg gagggaattt ctgtggaagg aaatactaat aataaagtag atgataaatt
    13081 ttctaaggtt aagaaaaagt ttggtagtgg aaaatttaaa gttgaattat ataaagaaaa
    13141 atcaaaatta aatagagaga ttgatgatat tcaagaaaag aaagcaaaga tattcttgga
    13201 aatgggaata ctgacatatc aaaaaattag agaagattct attaatgata atagttttga
    13261 taaattctgt gatgagttac tagaacttga taagttaatt tatgaaaaaa atatggaaat
    13321 taatgaaatg gaaatggcag aaagtaatgt aacttgtgag tgtggttatg ttggaaatgt
    13381 aaatgataaa tattgtgctg aatgtggtaa aaaatttgaa ttggaaaatg aatgtgatga
    13441 ttttataatt tgtggttatt gtgaaagtga gatagataca gaggctgaat tttgtccatg
    13501 ctgtggaaga aaaattataa tggatttaga ataatattgg gaaacctatg tatagtatac
    13561 atgggttttt ttattgaaat tatttaaatg gacttataac agtagttata taaaatgaaa
    13621 ataaacacca aaaaaatgaa ataaaatttc ttttaaatgt aaaaaacaag ctaatatata
    13681 aaataaatca gtaaaaatat agatgcgaga aaaaatatga aaaaatattg caaagaaaaa
    13741 gttttcatgt tattattaat acataaatca agaaaataaa tttcagaaac gaggtaattt
    13801 aaaaaatgct agataaggta aagggaagat taatagtatc atgccaagct ttagaaaatg
    13861 aacctcttca tagtcctttt ataatgggga gaatggctaa ggctgctatg gaaggtggag
    13921 ctgttggaat tagagctcaa ggagttgaag atattattga aataaaaaaa gttactggac
    13981 ttcctgttat aggtattata aagagaaact atgaagattc agatatatat ataacgccaa
    14041 ctaaaaaaga agttgatgaa cttttaacaa cagggtgtga aatgatagca ttagatgcta
    14101 ccaatagagt tagaccaaat aatgaagact taaaagaact tataaagtat ataaaagaaa
    14161 acggtgttct agtaatggca gatatttcaa attatgatga ggctatcaaa gcacaagagt
    14221 acggtgtaga ttgcgtttca actacactat ctggatatac tccatatact aaaacattag
    14281 aaggtccaga ttttgtatta atgaaaagat tagttaaaga tttagaaata cctgtaatag
    14341 ctgaaggaaa ggtaaatact cctcaagatt taaaaaaggt ctttgagttg ggtgttcatt
    14401 catcagtagt aggttcagca ataacaagac cacaattaat aacagaaaaa tttgttaaag
    14461 caattgaaat taattaaaaa ttaatttata aattaaaaaa ttattatatt taactatatt
    14521 tgaaaattaa aattggaggt aaagatatga gaacaacaga tatgaaggga atttattcag
    14581 cattattagt ttcatttgat aaggaaggaa atataaatga aaaagggtta agacaaataa
    14641 ttagacacaa tatagatgtt tgtaaagtag atggtcttta tgtaggagga agtacagggg
    14701 aaaacttcat gctttcaact gatgaaaaga aaagaatatt tgaaatagct aaagatgaag
    14761 tgaaagaaga aataaaatta atagctcaag ttggttcagt taatttaaaa gaagctgtag
    14821 aacttgctaa atttacaact gatttaggat atgatgcaat aagtgctgtt acaccttttt
    14881 actataaatt tgattttgaa gaaataaaac actattataa tacaataata aattctgtag
    14941 ataatagatt aataatatac tctataccat ttttaactgg tgttgatatg agtttagacc
    15001 agtttggaga attatttgaa aatgaaaaaa taataggtgt taagtttaca gcagcagatt
    15061 tctacttatt agagagaatg agaaaaacat tcccaaataa attaatattt gcaggatttg
    15121 atgaaatgat gttaccagct acagttttag gtgtagatgg ggcaattggt tctacattca
    15181 atgtaaacgg tgtcagagct agacaaatat tcgaattaac taagaatgaa aaaatatcag
    15241 aagcacttga agtacaacat gtgactaatg atttaataac agatatatta ggaaatggct
    15301 tatatcaaac aattaaatta ctacttgaag aacaaggtgt tgaggctgga tactgtagac
    15361 aacctatgaa agaagcaact gatgaaatga aatcaagagc aaaagaaata tacagaaagt
    15421 atttttaata aaatactttt agtatgggag gattagtcaa atggtaggat ttacttggat
    15481 agattttgca atactagtgg tttacttatt ggcagtttta tttgcaggat tgttattttc
    15541 aaaaaaggaa atgaagggaa aagagttctt caaaggtgat ggaactattc cgtggtgggt
    15601 tacatcagta tcaatatttg ccacattatt aagtccaata tcatttttat cattagcagg
    15661 aaattcttat ggtggtactt ggattttgtg gtttgcacaa ttaggtatgt ttatagcaat
    15721 acctttgaca ataaaatttt tcttacctct atatagtagg ttagaaatag atacagcata
    15781 tgaatactta gaaatgagat acgaaagtaa aggtcttaga gtacttggag ctttgatgtt
    15841 tataatatat caaataggac gtatgtctat tataatgtat cttccatcaa tagttctggc
    15901 tggtcttaca ggaatacctg taaatgtact gataatagtt atgggtgtaa tagcaataat
    15961 ttactcatat acaggtggat taaaggctgt cttgtggacc gattttatac aaggaatggt
    16021 attaatagta ggtgttacag ggacattgtt ctatttaata gcaagtataa atggtggttt
    16081 tggaacagta atggatactc ttacaactgg acacaagttc ttagcaagta atgaagttat
    16141 gtttgataaa aatatactat ctacaagtgc atttataata tttgttggag ctggtcttaa
    16201 tactttttca tcatatgtat cgagtcaaga tatagttcaa aggtttacta caacaactga
    16261 tataaagcaa cttaataaaa tgacatatgg aaatggtgtt ttatcaatgg gacttgcaac
    16321 agtattttat ctaattggaa cttgtttatt tatatactat actcaaaacc cagatttagc
    16381 tcaaacagtt caacaagacc aagtatttgc atcatatata gcttatgaat taccagtggg
    16441 tataacagga atactacttg cagcgatata tgcagcttct caatcaactt tatcgacagg
    16501 gcttaattca gttgctacaa gttggacttt agatatacaa actatcataa caaaagatat
    16561 aagtatggaa aagcaaacta agatagcaca atatatatca ttaggtgtag gtatactttc
    16621 tatagctgtt gcaatagtat tagcaaatgg agaaataaag tcagcatatg aatggttcaa
    16681 tagttttatg gggctagtac taggtgtttt agcaggaata tttgtacttg gtgcattttg
    16741 taaaaaagca actaaaatgg gagcatatgt tggattcata gtatcagcaa ttttagttgt
    16801 ttatttaaaa taccgtatgc cagaagtaac ttcttgggca tattctctaa taacaatcac
    16861 gacttctgta gtggtaggta caatagttag tgcaatagaa gctaaagtta aagcaaaagt
    16921 atctttacca aaagctgaga ctactgttta ttatgaaaaa taatatttaa atgataaatt
    16981 gtcttataga gtgattagat aaataattta gttactctat aagattgtat aatatacttt
    17041 gtatacaaaa gtataaaaat agactttata attatatagg gagatagtgc ttatgatatt
    17101 tggaaatata aatcatagta agacatattc aacattgcat gaagatttac ttagatgttt
    17161 tgaatatgct aaagataatt cattaataga ttatgaaaaa ggtacttata caatagatgg
    17221 tgatgatatt tttgtgaata ttgtagagta taaaacttgt gaaaaagaag atagattctg
    17281 ggaagctcat aagaagtata tagatgttca tttgatgctt gatggatgtg aacgaataga
    17341 tataaatttt atagaaaatt tagaacaaaa aatatatgaa gaaaagggcg atttcttgcc
    17401 tcttgatggt aaaaataatg gatacatgga acttagaaaa ggtgattttt tagtttgtta
    17461 tccggaagat gctcatatga caggaataaa agttttagaa aaagaaaata tcaaaaaagc
    17521 tatttttaag gttttggtta gataatgata atttatataa ccactagggc tgaaaatagt
    17581 gatttaactt tcagcgatta gtgagacttc gtaaatttta gttagattac tattttcagc
    17641 cttagttttt tatgagaaaa ttaaaaataa ttaaaagctt aaaattttgt aaaggagtta
    17701 acttatggaa aatatagatg tattcttatt aataggacaa agcaatgcta gaggattggg
    17761 aaatccaaaa gagagcatca ttccaaatga aaattgtttt gaatatttga gtactgatga
    17821 aattataaat atgagatgtg agctagagac ttcagaaggt gatggtacta tagcacctgc
    17881 attttcaaat gaatggaata agcttactgg aaataaagtt tgttttattc acaatgcaaa
    17941 agatggttca agaataaaaa actggaatca tgataataac tggtttctaa atgacactat
    18001 agaaaaattt aatacaggct gtactacctt aagtaaacat tataatatag aaaataaata
    18061 cgttatttgg attcaaggtg aaagtgatgc aaaatatggt agtgatgtat tgtactataa
    18121 agaaagtcta aaaaaaattg cgtataggct taaagaagaa tgtatgattg ataaaatgtt
    18181 tgtaagttta actggttatt ggcttggaga agatgaatat tttattagaa caagacgaat
    18241 tgcagcagca caggagtcgg cttgtagtga atgtgatata ttatgtgtag gaagcaaaat
    18301 tgctatgcag tttcatgaca gaggattaac tattgatgat gttcattaca ctcaagaagg
    18361 tcttaatatg ttaggagagg acttatgtaa aaatatttat aagtatcata taaccaaaga
    18421 aaaaagtgta ttaagtgata ctatagactt atcagaagca aggaaatata tctgtgaatt
    18481 ggaaaagata agtaaaagat ttgtgtaata taaaatttta aatagagttg ttaatttata
    18541 aaaataattt gtatggagat atgttatgaa aaattacgtt tgtatagatg ttggaggtac
    18601 ttcaataaaa tatggtttta ttagagaaga tggatttata attgataaat caagtcttga
    18661 tactgaagca aaggaaaaag gtggagaagg aatattagcc aaaataaaag atatagtaaa
    18721 aaaatatata gaggaaaatg aaataagtgg tatatgtata tcaactgcag gtatggttga
    18781 cccagttgaa ggtaaaatac tatttgcatt agaagaatta attccaaact ataaggacat
    18841 gcaattaaaa aaagaagtag aaaaagagtt taatataaaa tgtgaagttg aaaatgatgt
    18901 taattgtgct ggacttggtg aaatgtggct tggagcaggt agaggtgcaa catcttctat
    18961 atgtttaaca ataggtactg gaattggtgg atgtattata ataaataata aactgataaa
    19021 tgggtttagt aatagtgctg gtgaagtagg atatatgaat gtaaatggaa gttcttttca
    19081 agaattggca tctactagca gtctaattaa aaaagtagca aaaataaaaa atttgaatga
    19141 aaatgactta aatggaaaaa taatttttga tttagcaaag aataatgatg aagattgttt
    19201 aaaagaactc gataatatga taaaatcatt agcagttgga atcgcaaata tatgttatgt
    19261 aataaatcca gaagtggtaa ttttaggtgg tgggattatg gcacaagaaa agttcctaaa
    19321 accaaaaata gacaaagcat taaaggaggt tcttatagag agagtttaca aaaacactaa
    19381 tatagaattt gcaaagagac aaaatgatgc aggaatgctt ggagcattat ataatttttt
    19441 aaacaaaata taaagaatag aagggttttt aatgagtatt ttagaacaat tggaatcacc
    19501 aacttttaaa gtcacaaaat cagataaatt attaatagct tatataaaag aaaatataga
    19561 tgatgtattt tataaaccaa tatcacaaat agctaaagag agcaatattg gtgaagcaac
    19621 tataactagg tttgtaaaaa aaatgaattt taatggatta caggatttta aagttacttt
    19681 agcacaagaa atatcaacta tcaataaaaa aaatattata aataaaaata tacaaaatga
    19741 tgagccagct ttggatacag caaaaaaact tttaagttca aatgtaacca ctttagagaa
    19801 cacagtagag ataatcaata gtaaggatgt acatgactgc gcaaggctta taataaatgc
    19861 aaagaaagtt tacttcatag gtattggata ttctggtata atagcacagg attcaaacta
    19921 taaatttatg agaataggtc ttaattgtgt aagttttgac agtagtcata caatgataat
    19981 gatgtcttcc ataatggaag aaggagattt aataattgca atttcacatt ctggtgaaac
    20041 agaggagatt ataaaaactg taaagcttgc aagagccaat aatgctaaaa ttatatcaat
    20101 tactgaaaat aaaaattctg aattaaagga tatttcagat gtacacttat cttatgtatc
    20161 gggagaaaca gtactggaaa ccggttcaat atcttctaaa ttagcacaat ttttcattat
    20221 tgatttagta tatacacagg tagtaaaaga actttctaat gaagctattg aaaggaaaat
    20281 taaaactaca aatgctataa aattgtttaa aaatgaataa aataagaaat ttgtaatgtt
    20341 ttatagagct ctcttaaaaa tttaggaatg gagagatatt acatgtctaa attaaaagat
    20401 tataatattg ataaagtaat aatttttaat aatttaagta ctaaaacgaa gaatcaactt
    20461 aaagaaaaag ttaaactaaa aagattacaa aaaaaagaaa ttttatttta tgaaaaagat
    20521 agcttagaca gtgtttatat acttttagaa ggaaaggtat ctatttttaa gataagtgaa
    20581 aatggagaga gaaaagtaat tttcatatta aatagtgggg aagtcataaa tgatattaca
    20641 cttgacgctt ctaaaaactc tactgttggc tgtgaagcat ttgaaaattc aattgtagct
    20701 tattatagta ttgaagaatt tttagaaatt atgcaaaatg attttcaact tacaaaggat
    20761 attatttctt atatggaaag aagaataaga cgtttatata gacagttgaa aaattctata
    20821 tctataaaag tagataaaaa acttgcagca aaattatata ggttaagtag agaatttgga
    20881 gtttgctgtg gagaatggac tttactaaat gtaaatatta cagttacata tttagctgat
    20941 atgcttggct gtaaaaggga gactgtttcc agaatgataa aggtattgca aaaagaagaa
    21001 cttattaaaa ttgacaataa aggtttttat gttaaagaaa ctgaattatc aaggtatttt
    21061 aaaaataatt aattatgatt aagtaagagt attattagaa ttttaattaa ataaaaatat
    21121 tattaagaga atctatttat agattctttt ttattgtcta atttattaat ttttatttta
    21181 ccctattgaa ttgtataaaa aaacaaataa gattcttttt tattcaaaaa acttactaaa
    21241 tttttgatta tcttttcata agttggtaaa tgccgatata tcccgtattt gagggcttta
    21301 tcggtatttt ctttttggaa gataccttgc ataagctggc atttaccagc atgaaaatgc
    21361 aaccaaaagt agtaaatgag tagtaaatat acgttccgat attaacaagc cagtctttcc
    21421 agttctgctt ttgcagattg gaatgtaccg tgtgcgtagt agccaagcgt catggttatg
    21481 ttagcgtgtc ccatgagata ttgcagggtg ttcgggttca ttcccttgtt tgccatattc
    21541 gtacaatagg tatgtcggaa tgaatgtggt gtaatgtttg gtaacttgtc tttgtggtat
    21601 ttgttatact tcttaatcag tcctcgtacc atacccacat agtttccagc gactttaggc
    21661 aatccctcac ggtttaagaa taggaaattg ctgtaaccac caacaaccag cggttgagct
    21721 tttactctgt tctttagtat tctttggagt gcttgataag ccctttccgt caatggaatt
    21781 tttcgttttc cgttctttgt ttttggagtg tcaatatagt agccgatttc gctatctctt
    21841 aatagctggt ggtctatatt gagtattctg ttctgcatat caatatgcgt tgtcagtccg
    21901 caaaattcag aaatacgaag tcccgtttcc agaagaagca caacctcatc ataatacttg
    21961 ctgtaaatct tatccgtttc cataaaggca agcaggcgtt cttcctgctc tggcgtaaga
    22021 ataactttcg gctcggtatc atcttccaga acatcactta gcttaaattc aaacgggttc
    22081 tttctgatac agtcgtcttg tatcgccata taaaatgacg ctttcaagga acgcttatag
    22141 ttgtcaatcg ttttgtaggc atatcctctt tcactcattc tgatagccca ctctttagcg
    22201 tccgactgtt tgacggtatc aatcgctctc atacccaatg ggtcattttt cagagcgttc
    22261 ataagatact gtcgtccttt ttccgtagct cgcttgatgt tctttctttg gctgttcttc
    22321 ttgtcgtaaa gctggcagac tgtcatttta ccgcctgccg tgtcaatacc gtcatcaagg
    22381 tcttttttta tctgtgcttc tttttccctc aacgatatat catcacgttt tccagcaggc
    22441 gttttgtctg tcggtacaag tttccaagca taaataaact gtggctttcc gtatatatcg
    22501 gtatatttat aaacgtatct tccgtctttt cgctggctct ctccattacg caaattgcga
    22561 tttttactgt cttttcgttt cacattagac atagtgtaaa gctcctttcc gtcatggaat
    22621 gagccgtgat acgctatact tattatacca tatccacggc tctatgacat tagatttcgt
    22681 ccaatgtatc tatgattttt tcaaattgtt ttcgctttat ctgaatacgg ttgccgttca
    22741 cgataaccca gccagcgtca atattttctt cggctaattt acgcaacttc ttttctccaa
    22801 tgcggaagta tttggacgct tcttcaatcg tcagtgtata tttttcccag ataggcacat
    22861 cagtattatt cataatttat gcaccccctt tactgtgtgt cagtctataa gttatataaa
    22921 caggcagacg gctttggaaa gctccattag tatttcaact attcccattc ttgtgggcag
    22981 aaccgcacca tgcggaagta tcattatgct gtaagggtag gtcatggcaa aacgactttt
    23041 ccaacggtcg ctctcggatc actgcgtggg tcgctcgctt tcttttggaa aggtcatggc
    23101 gtacagttcc cgtggctctc tatccttaca aacgtatctg tctgctttat tcagttttca
    23161 aagagctgtg gcgaaagcgg tatgctttca tgtaaaagca ggagcagagc aggaaagagg
    23221 ggattgaaca aatcatgctc tgcgttactg ctggttattc ttcttcaatt tctaaggcaa
    23281 tatcaaaccc taaaatcatt ttgataagtg cttctcggat aagtcctttt aactccatat
    23341 ctacaacgat ataaacatta ccgtattcat catagagtgg acgcaaacag cacttcgata
    23401 tgtaagggtc ataaaatgca agtacctttt caatcgcttt ttcgtccccg tccatagctt
    23461 gtgaaagcaa gtagtaagac ggcttcttaa atgtgtgttt catttgctat cgtttctcct
    23521 ttaatagttt tctcataagt gccaatgaat tgtggcggtt ctgaaaaact ccgcttctgg
    23581 aaatgttttg ctttttggcg atttcttcat tgttcatttc caaaaagtaa tacatcaaca
    23641 aagtttctcg gttacgttcg gataactgtt tcaaggcttc tgccaattca tcatcataga
    23701 cacgaatatc attaccgcat acattgaaaa tcgtatagtc tgtttcgtag tcgtcccata
    23761 cagccaagtt ttcaaccatg atttctggaa gttcacaaaa ggaaatttct ttttcttttc
    23821 ttcgcttcaa tccctgctga tagtccttga caacatgacg gacaactttc ttcaaacagc
    23881 tttcaaaacg gcattgaaca gttttctgga agtcagacgg tttcatcaat ctcaccccct
    23941 ttccgttatg acgtgaaaag tgtttatccc tctttccgca ccatataggg aatggcaagt
    24001 gtgatttgtt aagttgaaac cagaaaaaat cgaaaaaact ttttagtaaa acaaaaacag
    24061 cccgtgtgaa tgtgaataca caaacggact gctttataaa tgctatctgt atgaattttt
    24121 aactcttgta gagggtagaa tgattgtaat actgaactaa aatatttttt cagttgggaa
    24181 cagcaaagta ttattccata tacaatcatg gcgtagcccc ctttaccaga gctatacctt
    24241 gtgccaccaa tgaaaaagga cggctctggc tatatccaaa accgccccgt tatgttttca
    24301 agacgcacaa aagtatatca tctcggaacg gttatggtga tttaaaatga gaaaaacaaa
    24361 agaaacacat acttttgatt tcagaccgct agggctggca atcagagaag cccgtgaaaa
    24421 agctgggctt tctcgtaatg atttaggcga taaggtattc tatggggaa
//
LOCUS       DAJMZY010000057        24363 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.057, whole genome shotgun sequence.
ACCESSION   DAJMZY010000057 DAJMZY010000000
VERSION     DAJMZY010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 24363)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24363)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24363
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.057"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            172..1977
                     /locus_tag="OE968_002202"
     CDS             172..1977
                     /locus_tag="OE968_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HCP7219480.1"
                     /translation="MLSKLKEFQQEMIKYTETVASVLDVDIEIVDDRLIRISGTGLYK
                     SKINESVVTEGFIYDNVIQTGQELVVLDICDNQLCIECSHYMKCLNKVIIAVPIKYNN
                     RTIGVIGAISTDKTKKVEISAKIDNYLKFVNHICDLISMKIEEHEASKNSSRKMDMMI
                     EIIENVEKGVIILDINSKISYINNIALKKLDIDKNIIENIVNIVSVESSSNGHELLEI
                     DIDNKIYNINAKIIPVYPYINQYDKIIIFDKTYINHKGHGKVNSGWGNSDIESIIGNS
                     EAMLKVKERTKKLAKSNSTVLITGESGTGKELIARAIHAEGSRWNKPFIAINCAAIPE
                     NLLESELFGYIKGAFSGASSGGKVGKFELANEGVIFLDEIGDLSMPLQAKLLRVLQER
                     KFARIGSNKLIDLDIRVIAATNKNLLKLVNEGKFRDDLYYRLNVIPINLPPLRERKDD
                     IEAIMMKFASKYSLELGIQLNKIEENVMNMLINYNWPGNIRELENAVEYMMNLVGDDG
                     IIYKDMLPLDILNYYNINGNIYKNKDVNIIFEDDIVGGIVENQERILSIKELELTYIN
                     KLLNKYGRDTKTKKKIAKDLGIGLATLYRKLEEEQ"
     gene            2054..2591
                     /locus_tag="OE968_002203"
                     /pseudo
     CDS             2054..2591
                     /locus_tag="OE968_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427977.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="2'-5' RNA ligase family protein"
     gene            3205..4419
                     /gene="dpaL"
                     /locus_tag="OE968_002204"
     CDS             3205..4419
                     /gene="dpaL"
                     /locus_tag="OE968_002204"
                     /EC_number="4.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopropionate ammonia-lyase"
                     /protein_id="HCP7219481.1"
                     /translation="MREIKWKLNNLPKSEEKEKGIEFLKDEEIAKAKAFHESFPQYEK
                     TPLVKLDNLAKSLGVSGIYVKDESYRFGLNAFKVLGGSYSMGRYLAQRLNTDISELGY
                     DKLTSKEIKEKLGEITFFTATDGNHGRGVAWTANKLGQKSVVLMPKGSSEFRLNKIKG
                     EGADASITDLNYDDAVRLANDYAEADDHGVMVQDTAWDGYEEIPAWIMQGYGTMAKEA
                     IEQLKEYGVDRPTHVFVQAGVGSLAGAVQGYVASIYDECPITVVVEADEADCYYKSAE
                     AGDGKPRFVGGDMPTIMAGLACGEPNTIGFEVLKNYSSAFVSAPDWVSAKGMRILGNP
                     LRGDEKVISGESGAVTTGALVSILESEDLKDLREALKLDENSKVLLISTEGDTDPDKY
                     RDIVWNGECQSK"
     gene            4752..5939
                     /locus_tag="OE968_002205"
     CDS             4752..5939
                     /locus_tag="OE968_002205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgeY family selenium metabolism-linked
                     hydrolase"
                     /protein_id="HCP7219482.1"
                     /translation="MLNETRKKQLTEVCQDLIRNASYSGQEENVVKAIEENFALLGFD
                     SWSRDRYGNIVGCIKGNKPGKKILFDGHIDTVPVPDASKWSVPPFEARIVDGKIYGRG
                     TSDMKGQVSAMMAAVSYFAEDTNKDFEGELYVAGVVHEEIFEGVSAREISKAVQPDYV
                     VIGESSELNLKIGQRGRGEIVVETFGKPAHSANPEKGINAVYKMANVIQKIQQLVPPT
                     HPVLGDGILVLTDIKSSPYPGASVVPDYCKATFDRRLLVGETREGVLAPIQALLDEMM
                     KEDPELNAKVSYAVEKADCYTGNTIESERFFPGWLYDEEDEFVQAAYKGLKEAGIDSE
                     ITQYSFCTNGSHYAGEAGIRTIGFGPSKENLAHTIDEYIELDQLFKGAEGYYGILKSV
                     YKK"
     gene            5955..7538
                     /locus_tag="OE968_002206"
     CDS             5955..7538
                     /locus_tag="OE968_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacylase"
                     /protein_id="HCP7219483.1"
                     /translation="MRTLIKHGLIVDGNKTPAYEGDILIENEKILKISQDLNEEADKV
                     IDAKGRVICPGFIDTHSHSDLVILVNPYNEVKIRQGITTEVLGQDGISMAPLPQEHIS
                     SWRKNLAGLDGESDEIDWKYETTENYLKMMDYNGVGLNETYLVPHGNVRMEAMGLEDR
                     PATKEEIQKMCEITERELKAGAIGLSTGLIYIPCAYSLTEEIIEMCKVVAKYDGVFVV
                     HQRSEADTILTSMEEIIEIGKQSGVKVHFSHFKVCGKANWKYIPQVIELLEKAEKEGI
                     RVSFDQYPYAAGSTMLGVVLPPWAHSGGTDKLIERLSDENERAKMKKDIANGIEGWDN
                     FIEFAGIDQIFVTSVKTEKNKDTIGKSLLEIGKMRGKDPLDATFDLLKEEENAVGMVD
                     FYGLEEHIIGFMKRDEQNVCTDGLLAGKPHPRAYGSFPKILGRYVRELNVLTIEEAVY
                     KMTKKAATSFSIKDRGELKEGYFADIVIFDKDTVSGCDDFINSMQYPTGIDYVIINGN
                     CVVEEGKYNKIKAGKVLKN"
     gene            7566..8894
                     /gene="ssnA"
                     /locus_tag="OE968_002207"
     CDS             7566..8894
                     /gene="ssnA"
                     /locus_tag="OE968_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative aminohydrolase SsnA"
                     /protein_id="HCP7219484.1"
                     /translation="MILVGNGRLISQDSLNPYMEDGCVVINDNLIEDIGTTEEMKAKY
                     PVHEFIDAGKKIIMPGLINSHMHIYSSFARGMAVPGKPSENFLEILNNLWWRLDKQLT
                     LEDTKYSAYATYIECIKNGVTTVYDHHASPNAIEGSLFTISDVAKDLGIRTCLCYEVS
                     DRDGGNTIQQGINENVNFIKYAQKDDTDMIKGMFGLHAAFTLSDDTLNKCASEMAGLD
                     TGYHVHVAEGLADLQYNVDKYGKRVLERFNDFGVLKEKTIAVHCIYISAEEISLLNKT
                     NTFVVHNPESNMGNAVGCSPAIELLKRGVTVGLGTDGYTSDMFESLKVANIIHKHHLK
                     DPRVGFEESQTMLFDNNRKIAKAYYKNDLGVLKKGAYADVIVVDYIPHTPLTENTIGG
                     HTIFGMSGRSVDTTIINGKVLMKDRKLINIDEESILAKSRELSQNLWNRI"
     gene            9039..10391
                     /locus_tag="OE968_002208"
     CDS             9039..10391
                     /locus_tag="OE968_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HCP7219485.1"
                     /translation="MSRDKSPKIAPVDERLPVSKSWVFSLQHVLAMCAGAVAVPMMIG
                     SAARLDHASIVFLINACLFMAGIGTLIQSVGIGNIVGAKIPVIEGTSFAAVAGMTAIA
                     SSYSDSQVAIQTVFGSVIVAGLFCILLAPVFEKLIRFFPSVVTGTVVMVIGISLFPVG
                     IKWITDNKLEAVEPNSLALALAVLAITLLSFKFLKGIWNSTAILVGIVLGTLLSMAVG
                     MADFSAVNGVGWLNLNVPLKFGMPRFEPSAILSLCLIMLVLMTESVGNMIAIHEMVDK
                     EVTGKNIKRGLFGDGISTALSGIFNSFPITPFGQNTGIVGLTGIKSRFIAVYAGVILL
                     VLGFLPKFAAIIGAIPKPVLGGVGFAMFGMVMVGGVKTLSKVKFDGTKNGVIVAVSVG
                     LSMIPLTNPDFYHNFPTWVQTIFHSGITTGSLSAVLLNIFFNELGSKKEKNNKVEEAK
                     "
     gene            10583..11692
                     /locus_tag="OE968_002209"
     CDS             10583..11692
                     /locus_tag="OE968_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HCP7219486.1"
                     /translation="MANLKVNLYGMEFLNPIMTAAGPGAKDGALCQEAAKGGAGAICT
                     KTISVLPADVPRPCMAKTNSGFLNTELWSELPKEQWIEEEYKKVKETGLPVIVSMGYS
                     AEQIAEVAPLVKPYADAVELSTHYVGTDVAPIVNALKAAKAVLDVPVFMKMSPHTDIQ
                     TIAKAVEEAGADGLVMINSFGPCMAIDVNTGYPIMGSKAGYGWLSGAPIRPLAIRCIY
                     EASQVVNIPIIGVGGITCGKDVAEMMMAGASAVQVCTEAILKGPSIYGKIAKELNEFL
                     DENGYADVNEIKGLTHKKMAARGFRTHSVAPVVDDNKCIKCKQCVTSCVYEALEVTDK
                     LNIDADKCFGCGLCVTRCPKGALSICYNQVEAMNE"
     gene            11975..13366
                     /gene="hydA"
                     /locus_tag="OE968_002210"
     CDS             11975..13366
                     /gene="hydA"
                     /locus_tag="OE968_002210"
                     /EC_number="3.5.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropyrimidinase"
                     /protein_id="HCP7219487.1"
                     /translation="MGIVLKGGKVVTSEKTYCADVRIEDEKIVDIGLDISKENDEIVD
                     VSDSYVIPGGIDTHTHFDLDTGVTKTADNFETGTKAAIVGGTTTILDFATQAKGCSLK
                     DGLEEWHEKAKDKSYSDYGFHMAITDWNDSVCNEMEDMVKEGVSSFKLYMAYKGSLQV
                     DDGVIFEALRKAEEIGGIIGFHCENGDIICELVDKAKSENNLSPKYHQLTRPAIMEAE
                     ATSRLMKIAEVANSKVYVVHLSCKESLEEVLKAKQRGVDVIVETCPQYLLLNDELYDL
                     DGFESAKYVMSPPLRNKENNEILWNAILDNQIDTIGTDHCSFNYKGQKELGINDFSKI
                     PNGSPGVEHRMSLLYTYGVCKNKISINKMVEVTSTNAAKLFGMYPNKGTIEIGSDADI
                     LVLNPNKKSKIEAKKQLQNVDYTPYEGYEVDCQIEHVYLRGKEVVRDGELICNTPSGR
                     YINRRLTKGAREW"
     gene            13360..15921
                     /gene="xdh"
                     /locus_tag="OE968_002211"
     CDS             13360..15921
                     /gene="xdh"
                     /locus_tag="OE968_002211"
                     /EC_number="1.17.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="selenium-dependent xanthine dehydrogenase"
                     /protein_id="HCP7219488.1"
                     /translation="MVEFILNGEKVVAKEGKKLLDFLREDMNITSVKNGCSEGACGTC
                     MVIIDGKATKACVFKTDKLAGKNITTIEGLSERERDVFAYSFASQGAVQCGFCIPGMV
                     ISSKALIDVNNNPTEDDIKKALKGNICRCTGYVKIIKAVDLAAKIFRENIDVPKVNCK
                     GLVGENLPRVDAVGKALGYSEYVDDMRIEGMIYGSAVRAKYPRALVKKIDIEEAKAYP
                     GVVAVLTAKDIPGTIKVGHLKKDWDTLIPEGEITRYLGDGIVLVAAETREALEEAKKL
                     VKIDYEELTPLSTTEDALREDAPKIHETGNILVKEHLVRGNAKEKIENSKYVVTKRYT
                     TPATEHAFLEPECAVAGPYEEDGVIIYSTDQGVFATQHECADMLGLPYEKVRVINKMV
                     GGGFGGKEDMSVQHHAALLAYHTKRFVKVQLTRKESIIVHPKRHATEMEFTTACDENG
                     YLTGMKATIISDTGAYASLGGPVLQRLCTHAAGPYNYQDIDITGTAVYTNNPPGGAFR
                     GFGVTQSCFATECNLNLLAEMVGISPWEIRYKNAIRPGQVLPNGQFADEGTAMAETLE
                     AVKEEYEKHPRAGIACAMKNSGVGVGIPDVGRCRLVIKDGKVHIRTSASCIGQGLGTV
                     MTQVVCETASLLPENVVHEVPDTHLTPDSGNTTASRQTVFTGEATKVASNKLKEALDS
                     GKTLLDLEGEEFYGEYESITDKMGCDKENPVSHVAYGYATQVVILDENGKLEKVVAAH
                     DVGRAINPISLEGQIEGGVVMGLGYALTEDYPVVNSVPTAKFGTLGLFKSTDIPEIQA
                     LIVEKNKDLLAYGAKGVGEICTVPTAPAVQNAYYVFDKEFRTELPLQNTPYSKKK"
     gene            16169..17515
                     /gene="rpoN"
                     /locus_tag="OE968_002212"
     CDS             16169..17515
                     /gene="rpoN"
                     /locus_tag="OE968_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HCP7219489.1"
                     /translation="MNFNNSLELTQSQKLIMTTQLKQSLSILNMSKLELEEEIKREAE
                     NNPLVEVEKSGEINWEEYIKDMDRSRRLDRTEISYNPDNEVNLENLVKYSSNLYEDLK
                     FQISLYKLTDKELEVCEYIIDSLDEDGYLRTEEKVIVDTLKIDEELFEKCLISVQQLE
                     PSGVGARSLSECLMIQMASLGIYNEILEEIVTKDLNLIANNKYKEISKKYNMSLQKCV
                     ELINIIKTLDPKPGRTCSVEKSVYIQPDVTVEKIDDEFIVYLNEKDSYQIRINSYYKD
                     ILKNSQSDESAKEFIKERLNSATGLMKNIESRKTTVLKIAEEIVKAQDEFLRKGTKYI
                     KPLKMKDIAEKLEFHESTISRGVNGKYMLTPFGVYEFRYFFSSAIETENNEMASSTSI
                     KKIIKETIKDENKKKPLSDDHISKLLKEKGINVARRTVAKYREELGIPSSSKRKEY"
     gene            18311..19333
                     /locus_tag="OE968_002213"
     CDS             18311..19333
                     /locus_tag="OE968_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HCP7219490.1"
                     /translation="MKNLLEIQKKLIPQAIELMERRYSILRQISLSEPIGRRTLSNVL
                     EISERIIRSETEFLKEQGLIDVAVSGMTITKEGSDLLDKLKDIMSDIMGLSKLQDRVR
                     EKLGIKRVILVPGSCDENGSLLKDVTRYGCEYFLGILKDGDIVSITGGSTMLEFSNVI
                     KTDKRYPNSTIVPARGSMGTDVEMQSNNIVASISKKLHSNCKLLHIPDELDESAMKTL
                     SQVPEIKTTLEYIKRTDILVFSIGRADVMAKRRKLPEDKVDEILSKNAVGEAFGYYFN
                     KDGEIVYKLNTVGIDLETVKQVKETIAIFAGTEKVEALLAISNMHKNMVLVTDEESAY
                     KILSLL"
     gene            19393..20400
                     /gene="gap"
                     /locus_tag="OE968_002214"
     CDS             19393..20400
                     /gene="gap"
                     /locus_tag="OE968_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HCP7219491.1"
                     /translation="MVKVAINGFGRIGRLALRKMMEQQDKFEVVAINDLTDAKMLAHL
                     FKYDTAQGRFNGEIEVKEGAFVVNGKEIKVTAERNPADLPWAELGVDIVLECTGFFTS
                     KDKAEAHIQAGAKKVVISAPATGDLKTIVFNTNSDILDGSETVISGASCTTNCLAPMA
                     KVLNDKYGIEKGLMTTIHAYTNDQNTLDGPHPKGDLRRARAAAGNIVPNTTGAAKAIG
                     LVIPSLKGKLDGAAQRVPVVTGSITELVCTLGKNVTVEEINAAMKEASNESFGYTEEM
                     LVSSDIIGISYGSLFDATQTKVMEVDGKQLVKVVSWYDNEMSYTSQLIRTLGYFAQLA
                     K"
     gene            20622..21824
                     /locus_tag="OE968_002215"
     CDS             20622..21824
                     /locus_tag="OE968_002215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HCP7219492.1"
                     /translation="MSMLNKKTIEDIDVCGKKVLVRCDFNVPLQDGVITDENRLNGAL
                     PTIQYLISKGAKVILCSHLGKPKGEAKPELSLAPVAKRLSEMLGKEVVFAADDNVVGE
                     NAKKATEKMENGDVVLLENTRYRKEETKNEENFSKELASLAEIFVNDAFGTAHRAHCS
                     TVGAGEFLQERVCGYLIQKELKFLGEAVANPVRPFTAILGGAKVSDKLAVINELLEKV
                     DNLIIGGGMAYTFLKAQGYEVGTSLLEIDKVEYAKEMMEKAKNKGVNLLLPVDVVMAD
                     HFAPDATPIVTEDANVKEDYMGLDMGPKTIANFVKTIKESKTVVWNGPMGVFEFENFA
                     NGTLSVARAMAELTDATTVIGGGDSAAAVNQLGFGDKMTHVSTGGGASLEFLEGKELP
                     GIAALDNK"
     gene            21850..22593
                     /locus_tag="OE968_002216"
     CDS             21850..22593
                     /locus_tag="OE968_002216"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HCP7219493.1"
                     /translation="MRKPIIAGNWKMHKTIKEALEFVNEVKDKVNSDKVEAVICAPFT
                     LLKDLKEATKGTNIKIGAQNMHFEEKGAFTGEVSPLMLKEIDMDYVVIGHSERRQYFN
                     ETDETVNKKVLKALEVGIDPILCVGETLEQREAGKTKDVCKVQVEKALENVLKDDLAK
                     VVVAYEPIWAIGTGKTATAEDANDVISYIREVIKGLYGELANEVRIQYGGSVKPSNVA
                     EIMGQSDIDGALVGGASLASNDYLDLVNF"
     gene            22602..24134
                     /locus_tag="OE968_002217"
     CDS             22602..24134
                     /locus_tag="OE968_002217"
                     /EC_number="5.4.2.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003228330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-independent
                     phosphoglycerate mutase"
                     /protein_id="HCP7219494.1"
                     /translation="MMKKPVALIIMDGFGYNKDVKGNAIAESKTPNLDRIKKEYPNTL
                     INASGLDVGLPDGQMGNSEVGHTNIGAGRIVYQDLTRITKSIKDGDFFTNKVLCEAMD
                     NAKENSLHVMGLLSDGGVHSHIDHLKAIIKMAKDKGVQKVYVHAFTDGRDTDPQSALE
                     YAKEVQASMDEIGVGEFATVSGRYYAMDRDKRWERVELAYNAMVRGIGEKANSIEEAI
                     QNSYDDGKNDEFIMPTVIMKDDKPVGSIKENDSIIFFNFRPDRARQITRALVCEEFDG
                     FKREDIKNFFVCLTEYDITIENVHIAFGPQSLANTLGEYLAKNGKTQLRAAETEKYAH
                     VTFFFNGGVEEPNKGEERLLIPSPKVATYDLKPEMSAYELTDKALDKLGEDKFDFIVL
                     NFANPDMVGHTGSIEAAIKAVETVDTCVGRLIDKIVELGGSAIITADHGNAEYMLDPE
                     TGKTVTAHSINPVPFIVVGQEYESAKLLDGGRLSDIAPTVLDMMKLEKPEEMTGHSLI
                     SK"
BASE COUNT         9836 a         2728 c         4856 g         6943 t
ORIGIN      
        1 catattataa ttaaggttac tatataaaac aaacttttta taaattaata ttgtctgttt
       61 taacgcaaat atataaataa gtaatgtttt atatatattt taaagagtga ctatatgtta
      121 aaatatagct aaactgataa tttggtaaat taaattctaa tgggggaaac tatgttaagt
      181 aaattaaaag aatttcaaca agaaatgata aaatacactg aaacagtagc tagtgtgtta
      241 gatgtagata ttgaaatagt tgacgataga ttaataagaa ttagtggtac aggtctgtat
      301 aaatcaaaga taaatgaaag cgttgttact gagggcttta tttatgacaa tgttatacag
      361 acaggtcagg aattagtcgt attggatata tgtgataatc agctttgtat agaatgttcc
      421 cattacatga aatgcctaaa taaagtaata atagcagttc caataaagta taataatcga
      481 actataggag taattggtgc tattagcaca gataaaacta aaaaagtaga aataagtgca
      541 aaaatagata attatttaaa atttgtcaat catatatgcg atttaatttc tatgaaaata
      601 gaagaacatg aagcgtcaaa aaatagcagt agaaaaatgg atatgatgat agaaatcatt
      661 gaaaatgttg aaaaaggcgt tataatacta gacataaata gcaaaatatc ttatataaac
      721 aatatagctc taaaaaaatt agatatagat aaaaatataa tagaaaatat agtaaatata
      781 gtatctgttg aatcttcctc aaatggacat gaattactag aaattgatat tgataacaaa
      841 atttataata taaatgccaa aataattccg gtatatccat atataaatca atacgacaaa
      901 ataataatat ttgacaagac atatatcaat cataaaggac atggaaaagt gaatagtggc
      961 tggggaaata gtgatataga gtctataatt ggaaattcag aagcaatgtt aaaagtaaaa
     1021 gagagaacta agaaattagc aaagtcaaat tcaactgtac ttataactgg ggaaagtggt
     1081 acgggtaaag agctaattgc tagggctata catgctgaag gtagcagatg gaacaagcca
     1141 tttattgcga taaactgtgc tgctattcca gaaaatctcc ttgaaagtga gctatttggc
     1201 tatataaaag gtgcatttag tggagctagt agtggaggga aagtaggtaa atttgaactt
     1261 gcaaatgaag gtgttatatt tcttgatgaa ataggagatt tgtcaatgcc tttacaagca
     1321 aagttactta gagttttaca agagagaaaa tttgcgagaa ttgggtcaaa taaacttata
     1381 gatttagata taagagtgat tgctgctaca aataaaaact tattgaaatt agtaaatgaa
     1441 ggtaagttta gggatgattt atactataga ttgaatgtaa ttcctataaa tttgccacct
     1501 cttagggaaa gaaaggatga tattgaggca ataatgatga agtttgcttc taaatattct
     1561 ttagaattag gtattcagtt aaataaaata gaagaaaatg taatgaatat gttgattaac
     1621 tataattggc cgggaaatat aagggaactg gaaaatgcag ttgaatatat gatgaatttg
     1681 gttggagatg atggaataat atataaagat atgcttccat tagatatttt aaactattat
     1741 aatattaatg gaaatattta taaaaataag gatgtaaata taatatttga agatgatata
     1801 gttggaggga tagtagagaa tcaagaaagg atactttcaa ttaaagaatt agagttgact
     1861 tacataaaca agttgttgaa taagtatgga agagatacaa agacgaagaa gaagatagca
     1921 aaagacttag gcataggttt ggctacacta tatagaaaat tggaagagga acagtagtaa
     1981 tataatatta aaatgatagg tatttgtgtg tttttataga taggtatttt tactttatgg
     2041 tggaggtgtt attatgcaat atgcgataga gctatattat gataaaaaaa cggaaaagca
     2101 actttttgat ttatctaaaa aaatcgctga tgaaaaaatt agtacgaagt acttagaatg
     2161 gaaaacaaga cctcatctta ctttggcttg tttcaatgat gtggatgagg cttgttgcat
     2221 agacaagcta aaggggtttg cacaaaacca taaggtaata cctgcttaca ttggttcagt
     2281 aggcatgttt aatgatacta aaacggtgtt tgtatcacct ataatgaata gcaatgtatc
     2341 agtttcagag agaattatat gaggtactac aagattttga ttcaaatggt tgggaatggt
     2401 accaccccaa tcgttgggta ccccattgca caatagcact tactggagat gatgaaagtg
     2461 aggctttttt tcgggcaagt gatgtattac tgcgtgagtt caaaaaaata agtggtgagt
     2521 ttgtctcaat aggattggtt aaaattacat ttcctgtgga agaaattttt acagtgaata
     2581 tgaataggta actttaactc tgttgtggat gttatgaata ttttgtatag tgcatttcat
     2641 cagataaatg cgaagttgcg aatttcgaca gctcaatagt cgcaagtagg gcacaatggt
     2701 acacatattg cacttttgct tattgggggg acgaccatgt aaacttctgt aagaagctat
     2761 gaaaagattt aagccatttt ggaggctttg ggtaataaag aatatttggg taataaagta
     2821 tataaattta tagagtttat gcgtaagaag gttatagcca tatatttata gaaaataaaa
     2881 gtagtaatat atctgacaaa acaatagaca tataaaaaat aagagcataa taaaggaaga
     2941 attaagataa ataaacgatt tctcgaattg ataattctcg tattgataaa aatttcccaa
     3001 tatgagaatt ttttctttta taaatcttat ttttcacact caaaatttat aaactttaaa
     3061 gaaattttat aaaagtatgt aattccaaca taaaaaaatt gtttttagaa taaataatat
     3121 tggcacggta attgctttgc tataaggcac aaagataaaa aattaaaatg acaccgaaaa
     3181 atttgaaagg ggaatataaa ataaatgaga gaaataaaat ggaaattaaa taacttacct
     3241 aaatcagagg aaaaagaaaa aggaattgaa tttttaaaag atgaagagat tgcaaaggct
     3301 aaagcttttc atgaaagctt tccacaatat gaaaagactc ctttagttaa attagataac
     3361 ttagcaaaat cactaggcgt aagcggaata tatgttaaag acgaatctta tagatttggc
     3421 ttaaacgcat ttaaagtttt aggtggttct tactctatgg gtagatactt agctcaaaga
     3481 ttaaatacag atatatctga gttagggtat gacaaattga cttcgaaaga aataaaagaa
     3541 aaattaggag aaataacttt ctttacagct acagatggaa atcacggtag aggagttgct
     3601 tggacagcta ataaattagg tcaaaaatct gttgtattaa tgccaaaagg ttcttctgaa
     3661 tttagattaa ataaaatcaa aggagaaggt gcagatgcta gtataacaga cttaaactat
     3721 gatgatgcag taagattagc taatgattat gcagaagctg atgaccatgg agtaatggtt
     3781 caagatacag catgggacgg atatgaagaa ataccagcat ggataatgca aggatatgga
     3841 actatggcta aagaagctat agaacaatta aaagaatatg gagtagatag accaacacac
     3901 gtatttgttc aagcaggagt tggttcactt gctggtgcag ttcaagggta tgttgcttca
     3961 atatatgatg aatgcccaat aacagtagta gtagaggctg atgaggctga ttgttactat
     4021 aaatcagcag aagctggaga tggaaaacca agatttgttg gaggagatat gccaactata
     4081 atggcagggc ttgcttgtgg agaaccaaac actataggtt ttgaagtgtt aaaaaattat
     4141 tcatcagcat tcgtttcagc accagactgg gtatctgcta aaggtatgag aatattagga
     4201 aaccctctaa gaggagatga gaaagtaatc tctggagaat ctggagcagt tacaactgga
     4261 gcattagttt caatccttga aagtgaagat ttaaaagact taagagaagc tttgaaacta
     4321 gatgagaact ctaaagtatt attaataagt acagaaggag atactgaccc tgataaatat
     4381 agagatatag tttggaatgg tgaatgccaa agtaaataaa agacttaagg aaaataaaaa
     4441 cttaacaaat aaatgaaaaa tttaaggaaa ataaaaactt aaataagtga aaactttaaa
     4501 taaaataaaa actaaaacaa atgaaaaatc taaataaatg aaaaagtaaa gcaaatgaaa
     4561 aattcaaaat aaaaactaaa taaaattaaa taaaaccaaa taaaattaaa ataaagtcta
     4621 aataaaaatt taataaataa aatataaaga aataaaaaat caatagatta agtgaaatgc
     4681 taataaatta aaaaagtgaa atatcaaaat aaaacgtcaa caaactaaaa attatatggg
     4741 ggaatatcaa aatgttaaat gaaacaagaa aaaaacaatt aactgaagta tgccaagact
     4801 taataagaaa tgctagttat tcaggtcaag aagaaaacgt agtaaaagct atagaagaaa
     4861 attttgcttt actaggtttt gatagttggt caagagatag atatggaaat atagtaggat
     4921 gtataaaagg aaataaacca ggtaaaaaaa tattatttga cgggcatata gatacagttc
     4981 cagttccaga tgcaagtaaa tggagtgttc ctccttttga agcgagaata gtagatggga
     5041 aaatatatgg tagaggaact tctgatatga aggggcaagt aagtgctatg atggctgctg
     5101 tttcatactt tgcagaagat actaacaaag actttgaagg tgaattgtat gtagcaggtg
     5161 ttgttcatga agaaatattt gaaggtgttt cagctagaga gataagtaag gctgttcaac
     5221 ctgattatgt tgtaataggt gaatcttcag aattaaactt aaagataggt caaagaggta
     5281 gaggagaaat agtagtagaa acttttggta aaccagctca ctctgctaat ccagaaaaag
     5341 gtataaatgc agtttataaa atggctaatg taatccaaaa gatacaacaa ttagtacctc
     5401 caactcatcc agttttaggt gatggaatat tagttttaac agatataaaa tcttctccat
     5461 atccaggagc atcagtagtg ccagattatt gcaaagctac ttttgataga agattattag
     5521 ttggagaaac aagagaaggc gtattagctc caatacaagc tttattagat gaaatgatga
     5581 aagaagaccc agaattaaat gcaaaagttt cttatgcagt tgaaaaagct gattgctata
     5641 caggaaatac tatagaaagt gaaagattct tcccaggttg gttatatgat gaagaagatg
     5701 aatttgttca agcagcgtat aagggattaa aagaagctgg aatagattca gaaataactc
     5761 aatactcatt ctgtacgaat ggaagtcact acgcaggtga ggctggaata agaactatag
     5821 gatttggtcc ttctaaggaa aatcttgctc atacaataga tgagtatata gaattagacc
     5881 aattattcaa aggtgcagaa ggatattatg gtatattaaa atcagtttat aaaaaataat
     5941 taggagatgg ttttgtgaga actttaataa aacatgggct tatagtagat ggaaataaaa
     6001 caccagcata tgaaggagat attttaatag aaaacgagaa aatattaaaa atatcacaag
     6061 atttaaacga agaagctgac aaagttatag atgcaaaagg tagagttata tgtccaggtt
     6121 tcatagatac tcatagccat tcagacctag ttattttagt taatccatat aatgaggtaa
     6181 agattagaca gggaattaca acagaagtgt tgggccaaga tggtatatct atggcccctc
     6241 tacctcaaga gcatatatct tcttggagaa aaaatttagc aggtctagat ggtgaaagtg
     6301 atgaaattga ttggaaatat gaaacaacag agaattattt aaaaatgatg gattacaatg
     6361 gggtaggttt aaatgaaact tatttagtac ctcatggaaa cgttagaatg gaagctatgg
     6421 gacttgaaga tagacctgct actaaagaag aaattcaaaa aatgtgtgaa atcacagaga
     6481 gagaattaaa agcaggagct ataggattgt ctactggact tatatatata ccttgtgcat
     6541 actcattgac tgaagaaatt atagagatgt gtaaggtagt agcaaaatat gacggagtat
     6601 ttgtagttca ccaaagaagt gaagcagata caattttaac ttcaatggaa gaaatcatag
     6661 aaattggaaa acaatcagga gtaaaagttc atttttcaca ttttaaggtt tgtggtaaag
     6721 caaactggaa gtatatacca caagttatag agcttttaga aaaagcagaa aaggaaggaa
     6781 taagagtatc ttttgaccaa tatccatatg cagcaggaag tacaatgctt ggagtagttt
     6841 tacctccttg ggcacattct ggaggaactg ataagttaat agaaagatta agtgatgaaa
     6901 acgaaagagc aaaaatgaaa aaagatatag caaatggaat agaaggctgg gataatttta
     6961 tagaatttgc tggaatagac caaatatttg taacaagcgt aaaaacagaa aagaataaag
     7021 atacaattgg taagagctta ttagaaattg gaaaaatgag aggaaaagac ccattagatg
     7081 caacgtttga tttattaaaa gaagaagaaa atgcagttgg gatggtagat ttctatggat
     7141 tagaagaaca tataatagga ttcatgaaaa gagacgagca aaatgtgtgt acagatggtc
     7201 ttttagcagg taaaccacat ccaagagctt atggttcttt ccctaaaata ctaggaagat
     7261 atgttagaga gttgaatgtg ttaacaatcg aagaagctgt ttataaaatg actaaaaagg
     7321 cagctacaag ctttagtata aaagatagag gcgaattaaa agaaggatat tttgcagata
     7381 tagttatatt tgacaaggat acagttagtg gttgtgatga ttttatcaac tctatgcagt
     7441 accctacagg tatagattac gtaattataa atggaaattg tgttgttgaa gaaggaaaat
     7501 acaataaaat taaagcagga aaagtactta aaaattaaat cttagcttta aggaggaata
     7561 aatttatgat tttagtgggg aatgggaggc taataagcca agattcttta aatccctata
     7621 tggaagatgg atgtgtagta ataaatgata atctaattga agatataggt actacagaag
     7681 aaatgaaagc taaatatcca gtacatgaat ttatagatgc aggcaagaaa ataatcatgc
     7741 cgggtctaat aaattcacat atgcatatat acagctcatt tgctagagga atggcagttc
     7801 caggaaaacc ttctgagaac tttttagaga tactaaataa tttatggtgg agacttgaca
     7861 aacagcttac actggaagat acaaaataca gtgcatatgc aacgtatata gaatgtataa
     7921 aaaatggtgt aacaacagtt tatgaccatc atgcaagtcc aaatgcaatt gaaggcagtt
     7981 tgtttacaat atcagatgtt gcaaaggatt tgggaattag aacgtgtctt tgttatgaag
     8041 tgtctgatag agatggtgga aatacaatcc aacaaggtat caatgaaaac gtaaacttta
     8101 taaaatacgc tcaaaaagat gatacagaca tgataaaagg aatgtttggg cttcatgctg
     8161 catttacact atctgatgat acattaaata aatgtgcttc agagatggct ggtcttgata
     8221 caggttacca tgtacatgtt gctgaaggac tagcagactt acaatataat gtagataaat
     8281 atggaaaaag ggttttagaa agattcaatg attttggagt actaaaagaa aaaacaatag
     8341 cagttcattg tatatatata agtgcagaag aaatcagtct tttaaataaa acaaatacat
     8401 ttgtagttca taatccagaa tctaatatgg gaaatgcagt tggatgttct cctgcaatag
     8461 agttattaaa aaggggagtt acagtaggat taggaactga tggatatact agcgatatgt
     8521 ttgaatcatt aaaagttgcc aatataattc acaaacatca cttaaaagac ccaagagttg
     8581 gatttgaaga atcacaaaca atgttatttg ataacaatag aaaaatagct aaagcttatt
     8641 ataaaaatga cctaggagta cttaaaaaag gtgcttatgc agatgttata gtagttgatt
     8701 atataccaca tactccattg acagaaaata caataggggg acacactatt tttggaatga
     8761 gtggaagaag cgtagataca actattataa atggaaaggt acttatgaaa gatagaaagt
     8821 taataaacat agatgaagaa agtattttag caaaaagtag agaattaagt caaaatctat
     8881 ggaatagaat ttaaataatt gatattaata tacaagtaag aaacaagaat ttagatgtta
     8941 aaaacagagc ttaaacaaaa ataggaattt aaatgaagta tataaataaa aaatatacgg
     9001 aatagaatat taaattaaat atagaaggga gacccaaaat gtctcgagat aaaagcccta
     9061 aaatagctcc agtagatgaa aggttacctg tatccaaatc ttgggtattt tcactacagc
     9121 acgttttagc aatgtgtgca ggagcagtag cagttcctat gatgatagga agtgctgcac
     9181 gactagatca tgctagtatt gtttttttaa taaatgcttg cttgtttatg gcaggtatag
     9241 gaacactcat acaaagtgtt ggtataggaa atattgtagg tgctaaaata ccagtaatag
     9301 aaggaactag ttttgccgct gtggcaggta tgacagcaat agcctcatca tatagtgatt
     9361 cacaagttgc aatacagaca gtatttggct ctgtaatagt agctggattg ttttgtatat
     9421 tacttgctcc agtatttgaa aaattaataa gatttttccc tagtgtggtt actggaacag
     9481 ttgttatggt aataggtatt tcactatttc cagttgggat aaaatggata actgacaaca
     9541 aattggaagc ggttgaacca aactcattag cattagcttt agcagtattg gcaataactt
     9601 tactttcatt taaattctta aaaggaattt ggaatagtac agctatattg gtaggtatag
     9661 tacttggtac actactttcc atggcagttg gaatggcaga ttttagtgca gtaaatggag
     9721 ttggttggct taacttaaat gtacctttaa aatttggaat gcctagattt gaaccatctg
     9781 caatactatc attgtgtttg attatgttgg tacttatgac ggaatcagtt ggtaatatga
     9841 tagctattca tgaaatggta gacaaagaag taacaggtaa aaatattaaa agaggtctat
     9901 ttggagatgg aatatctaca gcattatctg gaatattcaa ttcatttcca ataactccat
     9961 ttggtcaaaa tacaggaata gtaggtctta caggtataaa atcaagattt atagcagttt
    10021 acgcaggggt tatattgcta gtacttggat tcttaccaaa atttgcagca ataataggag
    10081 caatacctaa gcctgttctt ggaggcgtag gatttgcaat gtttggaatg gtaatggttg
    10141 gaggagtaaa aactttaagc aaagtgaaat ttgatggaac taaaaatggg gttatagtag
    10201 cagttagtgt tggtttgtct atgataccac taacaaatcc tgatttctat cataatttcc
    10261 caacttgggt acaaacaata ttccatagtg gaataacaac aggtagttta tcagcagtgc
    10321 ttttaaacat attcttcaat gaactaggtt ctaaaaaaga aaaaaataat aaagttgaag
    10381 aagcaaaata aaaataaaac aagtaaaaat ctatattgac ttaaagtcat taagcattaa
    10441 taaaaataat tcagagatat taataattca acaaaactat cttatatttt aaataatata
    10501 aaaaagtaaa taaataacga atacaaataa aagaatacaa tctaaatatt aaaaatattt
    10561 aatttaaggg agagataata atatggctaa tttaaaagtt aatttatatg gaatggaatt
    10621 tttaaaccca attatgacag cggcaggacc tggagcaaaa gatggtgctc tctgtcaaga
    10681 ggcagcaaaa ggtggagcag gagctatatg tacaaaaact atatctgtat taccagctga
    10741 tgtaccaaga ccatgtatgg caaaaactaa tagtggtttt ttaaacacag aattatggtc
    10801 agagcttcca aaagagcaat ggatagagga agaatacaaa aaggtaaaag aaacagggct
    10861 tccagtaata gtaagtatgg gatattcagc agagcaaata gctgaggttg ctcctttagt
    10921 aaagccttat gcagatgcag ttgaattatc tactcattat gtaggtacag acgttgcacc
    10981 aatagtaaat gctttaaaag ctgcaaaagc tgttttagat gtaccagtat ttatgaaaat
    11041 gagtcctcat actgacattc aaactattgc aaaagctgtt gaagaagcag gtgcagatgg
    11101 acttgtaatg ataaactcat ttggaccatg tatggcaata gatgtaaata caggataccc
    11161 tataatggga agtaaagctg gatacggatg gttatcaggt gcaccaataa gacctctagc
    11221 aataagatgt atatatgaag cttctcaagt tgtaaatata ccaataatcg gtgttggtgg
    11281 aatcacttgt ggaaaagacg tggctgaaat gatgatggct ggagcaagtg ctgttcaagt
    11341 atgtacagaa gcaatcctta aagggccttc tatctatgga aaaattgcta aagaattaaa
    11401 tgaattttta gatgagaatg gatatgctga tgttaatgaa ataaaaggat taactcataa
    11461 gaaaatggca gctagagggt ttagaactca ttcagtagct ccagtagtgg atgataacaa
    11521 gtgtatcaaa tgtaagcaat gtgtaacaag ctgtgtatac gaagctttag aagttacaga
    11581 taagttgaac atagatgcag acaagtgttt tggatgtgga ttatgtgtaa ctagatgtcc
    11641 aaaaggagct ttaagcatct gctacaatca agtagaagct atgaatgagt aataattata
    11701 tagaattttg gtaattaact tagagtaata ggtattagga taataaaata tatcagataa
    11761 acaaacacgc attatgcatt aataatacag tctaaagtta ataattttat tatattgatt
    11821 taactaaata ttagtttagc tgaatattaa tttaattagg tattggttta atcttaatat
    11881 agatttacta cgtataagtg aactaactag attactttaa gttaattttt tcatataaaa
    11941 taaattgata cattacaagt aaggtggagt ctatatggga attgttttaa aaggtgggaa
    12001 agtagtaaca agtgaaaaaa cttactgtgc agatgtaaga atagaagatg aaaaaatagt
    12061 cgatataggt cttgatatat caaaagaaaa tgatgaaata gttgatgtta gtgattctta
    12121 tgttatacca ggaggtatag atacacacac acactttgac ttagatacag gcgttactaa
    12181 gacagcagat aactttgaga caggaacaaa agctgctata gtaggaggaa ctactactat
    12241 attggatttt gctacacaag ctaaaggatg ttctttgaaa gacggattag aagaatggca
    12301 tgaaaaagct aaggataaat catattcaga ttatggcttt catatggcta taacagattg
    12361 gaatgactcg gtttgtaatg aaatggagga tatggtgaaa gagggagtat cttcatttaa
    12421 actgtatatg gcgtataaag gaagccttca agttgatgat ggtgtaatct ttgaagcatt
    12481 gagaaaagca gaagagatag gagggattat tggtttccat tgtgaaaatg gggacataat
    12541 atgtgaactt gtggataaag caaagtcaga aaataattta tctccaaaat atcatcaatt
    12601 aactagacca gctataatgg aggcagaagc tacatcaaga cttatgaaga tagctgaagt
    12661 tgcaaactct aaagtatatg tagttcactt aagctgtaaa gaatccttag aggaggtttt
    12721 aaaagctaag caaagaggtg tggatgtaat agttgaaact tgtcctcaat accttctatt
    12781 aaatgatgaa ttatatgatt tagatggatt tgaaagtgct aagtatgtaa tgtcaccacc
    12841 tttaagaaat aaagaaaata atgaaatatt atggaatgct attttagata atcaaataga
    12901 cactatagga acagaccatt gttcttttaa ttataaggga cagaaggaac ttgggataaa
    12961 cgatttcagt aagataccaa atggttctcc aggtgtagaa cataggatga gtcttttata
    13021 cacatatgga gtctgtaaaa ataaaatatc tatcaacaag atggtagaag taacatcaac
    13081 taatgcagca aagttgtttg gaatgtatcc taataaagga actatagaaa taggcagtga
    13141 tgcagatata ttagtcttaa atccaaacaa aaaatccaaa atagaagcaa aaaaacaatt
    13201 acaaaatgta gattatacac cttatgaagg gtatgaagtg gattgtcaaa tagaacatgt
    13261 ttatttaaga ggaaaagaag tagttagaga tggagaatta atttgtaata ctccaagtgg
    13321 gagatatata aataggcgtc taacaaaggg ggctagagaa tggtagaatt tatattaaat
    13381 ggagagaaag ttgttgcaaa agaaggcaaa aaacttttag acttccttag agaagatatg
    13441 aatataactt cagttaaaaa tggatgttca gaaggtgctt gtggaacatg tatggttata
    13501 atagatggta aagctactaa agcatgtgta tttaaaactg ataaattagc tgggaaaaac
    13561 ataacaacta tagagggatt atcagagaga gaaagagatg tttttgcata ttcttttgct
    13621 agtcaaggag ctgtacaatg tggattttgt attccaggta tggtaattag ttcaaaagca
    13681 cttatagacg ttaataataa tcctactgaa gatgatataa agaaagcttt aaaaggtaat
    13741 atatgtagat gtacagggta tgtaaaaata attaaagctg tcgatttagc agcaaagatt
    13801 tttagagaaa atatagatgt gccaaaagta aactgtaaag gtctagtagg tgaaaatctt
    13861 cctagagttg atgcagttgg caaagcactt ggatattctg aatatgtaga tgatatgaga
    13921 attgaaggta tgatttatgg ttcagcagtt agagctaagt atcctagagc tttagttaaa
    13981 aaaatagata tagaagaagc aaaagcttat ccaggagttg ttgcagttct aacagctaaa
    14041 gatattccag gaactataaa ggtagggcac ttaaagaagg attgggatac tttaatacca
    14101 gaaggtgaaa taactagata cttaggagat ggaatagttt tagtagcagc agaaactaga
    14161 gaagcgttag aagaggcaaa aaagctagtt aagatagatt atgaggaatt aacaccatta
    14221 agtactacag aagatgcgct tagagaagat gctccaaaga tacacgagac aggtaatata
    14281 cttgttaagg aacatttagt aagaggaaac gctaaagaaa agatagaaaa ttcaaaatat
    14341 gttgtaacta aaagatatac tacacctgct acagaacacg catttttaga gcctgaatgt
    14401 gcagtagctg gtccttatga agaggatgga gtaataatct attcaacaga ccaaggggtg
    14461 tttgccactc aacatgaatg tgcagatatg ttagggctac catatgagaa ggtaagagtt
    14521 ataaacaaaa tggtaggagg aggatttggt ggaaaagaag acatgagtgt tcaacaccat
    14581 gcagccttac ttgcatacca tactaagaga tttgtaaaag tacagttaac aagaaaagaa
    14641 agtattattg ttcatccaaa acgacatgcc acagaaatgg aatttacgac agcatgtgat
    14701 gaaaatggat acttaacagg tatgaaggca acgataatat ctgacacagg tgcatatgcc
    14761 tctcttggag gaccagtgct acaaagactg tgtactcatg cagcaggacc atataattat
    14821 caagatattg atataacagg aacagcagta tatactaata accctcctgg aggagcattt
    14881 agaggatttg gagttacaca gagttgtttt gcaactgaat gtaatctaaa tttacttgct
    14941 gaaatggttg gaatatctcc ttgggagata agatataaaa atgcaataag acctgggcaa
    15001 gttttaccaa atggtcaatt tgcagatgaa ggaacagcaa tggcagagac actagaagct
    15061 gtaaaagaag agtatgaaaa gcatccacgt gcaggtatag cttgtgctat gaaaaatagt
    15121 ggggttggag ttggtatacc tgatgttgga agatgtagat tggtgataaa agatggcaaa
    15181 gtccacataa gaacaagcgc ttcttgtata ggtcaagggc ttggtactgt tatgactcaa
    15241 gtagtttgtg aaactgctag cctacttcct gaaaatgtag tgcatgaagt tccagatact
    15301 catttaacac cagactctgg taatactacg gcttcaagac agacagtatt tacgggagaa
    15361 gctactaagg ttgcgtcaaa taagttaaaa gaagctttag actctggcaa aactttactt
    15421 gatttagagg gagaagagtt ttatggagaa tatgaaagta ttacagataa aatgggttgt
    15481 gacaaagaaa atccagtaag tcatgttgct tatggatatg caacacaagt tgtaattctg
    15541 gatgaaaatg gaaaattgga aaaagtagta gcagcacatg atgttggaag agctataaat
    15601 ccaatcagtt tagagggtca aatagaaggt ggagtagtta tgggtcttgg atatgctcta
    15661 accgaagatt acccagtagt taactctgtt cctacagcta agtttggtac attaggttta
    15721 tttaaatcta cagatatacc agaaatacaa gctttaatag ttgaaaagaa caaagattta
    15781 ttggcttatg gggcaaaagg tgtaggagaa atttgtacag ttcctactgc accagcagta
    15841 caaaatgcct attatgtatt tgataaagaa tttagaactg aactaccact acaaaatact
    15901 ccatatagta aaaaaaagta acaaaaaaaa gaaatattaa ataaaaaaat agatgaaatt
    15961 gtaaataaaa aaatagatga aattgtaaat aaaaaaatag atgaaattgt aaataaaaaa
    16021 atagatgaaa ttgtaaataa aaaaatagat gaaattgtaa ataaaaaaaa cccttttgca
    16081 taaggtatat tttaaatgat agaatataca tatacaggag ggtttttctt ttataaaata
    16141 agtttaataa aattgagagg tgagcagaat gaattttaat aatagtctag aattaactca
    16201 gtctcagaag ctaataatga ctacacaact taagcaatca ttatcaatat taaatatgag
    16261 taagttagag ttagaagaag agataaaaag agaagcagag aataacccat tagttgaagt
    16321 cgagaaaagt ggggagataa attgggaaga gtatataaaa gacatggata ggtcaagacg
    16381 tttagataga acagagataa gctataatcc tgataatgaa gttaatctag aaaatttagt
    16441 taaatattcg tcaaatttat atgaagattt aaaatttcag ataagcctgt ataaacttac
    16501 agacaaagaa ttggaagtct gtgagtatat aattgatagt ttagatgagg atggatattt
    16561 aagaactgag gaaaaagtaa ttgttgatac cttaaagata gatgaagaac tttttgaaaa
    16621 atgtttaatt agtgttcagc agttggaacc tagtggagta ggggcaagaa gtctttcaga
    16681 atgtctgatg atacaaatgg ctagtttagg aatatataat gaaattttag aggaaatcgt
    16741 tacaaaagac ttaaatttaa ttgcaaataa taaatacaaa gagataagta aaaagtacaa
    16801 tatgtcatta caaaaatgtg ttgaactaat aaacataatt aagacattag acccaaaacc
    16861 aggaagaact tgttcagtag agaaaagtgt atacattcaa cctgatgtaa cagtagaaaa
    16921 aattgatgat gaatttattg tatatttaaa tgaaaaagat tcttatcaaa taagaatcaa
    16981 tagttattat aaagacatat taaaaaattc acagtctgat gaaagtgcaa aagaatttat
    17041 aaaagaaaga ctaaattcag caacaggact tatgaaaaat atagagagta ggaaaactac
    17101 agtacttaag attgcagaag agatagtaaa agctcaagat gaatttttga gaaaagggac
    17161 aaaatatata aaacctttga aaatgaaaga catagcagaa aaattagaat ttcatgaatc
    17221 tactataagt agaggtgtaa atggtaaata tatgttaaca ccttttggtg tatatgaatt
    17281 tagatacttt ttcagtagtg ccattgagac tgagaataat gaaatggcat ctagtacaag
    17341 cataaaaaaa attataaagg aaacaataaa agacgaaaat aaaaagaaac ctttaagtga
    17401 tgaccatata tctaagttac taaaagaaaa aggaatcaat gttgcaagaa gaacagttgc
    17461 caaatatcgt gaagaattag gaatcccatc ttcaagtaag agaaaagaat actaataagt
    17521 aaaagacaaa tatcagtatg gtaaggggaa aaggctaatt aaaagatgaa tgtagattgg
    17581 gctaaaaatt ttatgaagta aaataataga atatggaaaa gtattaaaat gctataagat
    17641 attaaaaaac tggggaacat taaaacatta agatagcaaa gaacataaaa aactaaagaa
    17701 gattaaaaca ttaaagaaca ttagagcttt gaggaatatt agaactttaa agaatattaa
    17761 aatttataaa atataaaaat actaaaaaga attgaaaaac tggggaacat taaaatattg
    17821 taaaatgcta aaaaactaga aaacataatt aaataagtgc ttataaagaa tgattaaatt
    17881 aaataagtgt ttgtaaagaa taattagata ttagaaaaag aagaatacct agataaataa
    17941 actattatta aatttaataa tcataaaagg aaaacacagg gtataaataa aaatcttaac
    18001 tagataaaag taaacttagt tgtagataaa aataactaga aataaaagta actagaaata
    18061 aaattattta tagtaataaa tattagaatg aaaatataaa aaaatatata taaaaagcct
    18121 tatataaaaa gaaaaaatac tgtgatttga aaatggtgga gaaatatttt ataaaataaa
    18181 aaaataaaaa agtttttgaa aaactattga aatctatacg caaatcctat aaaataaaaa
    18241 tatcttgtgg gacttaaata aacactaggg acgaaaaaag tcccgaaagg aaagcaataa
    18301 ggagtatgtt atgaagaact tattagaaat tcaaaagaaa ttgattccac aggcaattga
    18361 acttatggaa agaagatact ctattttaag acaaatatct ttaagtgaac caataggtag
    18421 gagaacatta tcaaatgtat tagagattag tgaaagaata atcaggtcag aaactgagtt
    18481 tttaaaagaa caaggactta tagacgtagc tgtatccggg atgactatca ctaaagaagg
    18541 ttctgatttg ttagataaac ttaaggacat catgagtgac atcatgggat tgtctaagtt
    18601 acaagataga gtcagagaaa agcttggaat aaaaagggta atattagttc ctggaagctg
    18661 tgatgaaaat ggaagtttac taaaagatgt aactagatat ggatgcgagt atttcttagg
    18721 tattttaaaa gatggagata tcgtttcaat aacaggagga agcactatgt tggagttttc
    18781 aaacgttatt aaaactgata agagataccc aaactctaca atagttccag ctagaggaag
    18841 tatgggaact gatgtagaga tgcaatctaa taatatagtt gcttcgataa gtaagaaatt
    18901 acattctaat tgcaaacttt tacatatacc agatgagttg gatgaaagtg caatgaaaac
    18961 tcttagccaa gtgccagaga ttaagacaac tttggagtat attaaaagaa cagacatttt
    19021 agtttttagt ataggtagag cagatgtcat ggcaaagaga agaaaacttc cagaagacaa
    19081 ggttgatgag atattatcta aaaatgcagt tggagaagca tttggatatt atttcaacaa
    19141 agatggagaa atagtttaca aactgaacac tgttggaatt gatttagaaa cagttaaaca
    19201 agtaaaagaa actattgcaa tctttgcagg tactgaaaaa gtagaagcct tattagctat
    19261 atcaaatatg cataaaaaca tggttcttgt aacagatgaa gaaagtgctt ataagatatt
    19321 gtcattatta taaaagtcaa gacctagcac agagctagaa aacatacatt tactttatag
    19381 gaggtagcga aaatggttaa agtagctata aatggatttg gaagaatagg aagattagca
    19441 ttaagaaaaa tgatggagca acaagataag ttcgaagttg ttgcaataaa cgacttaaca
    19501 gacgctaaaa tgttagctca tttatttaaa tatgatacag ctcaaggaag atttaacgga
    19561 gaaatagaag ttaaagaagg tgcttttgta gtaaacggaa aagaaataaa agtaacagca
    19621 gaaagaaatc ctgctgacct accatgggct gaattaggag tagatatagt attagaatgt
    19681 acaggattct ttacatctaa agataaagct gaagctcata tacaagcagg ggctaagaaa
    19741 gttgttatat ctgcaccagc tactggagat ttaaaaacaa tagtattcaa cacaaacagt
    19801 gatatattag atggttctga aacagttata tcaggagctt cttgtactac taactgttta
    19861 gctccaatgg ctaaagtatt aaatgataaa tacggtatag aaaaaggatt aatgactact
    19921 atacatgcat acactaatga ccaaaatact ttagatggtc ctcatccaaa aggtgattta
    19981 agaagagcta gagctgctgc tggaaacata gttccaaaca ctacaggagc tgcaaaagca
    20041 ataggcttag taataccttc attaaaagga aaattagatg gggcagcaca aagagtacca
    20101 gttgtaactg gttcaataac tgaattagtt tgtacattag gaaaaaatgt tacagttgaa
    20161 gaaataaatg cagctatgaa agaagcttca aacgaatctt tcggatatac tgaagaaatg
    20221 ttagtatctt ctgacataat cggaataagc tatggttcat tatttgacgc tactcaaaca
    20281 aaagttatgg aagtagatgg aaaacaatta gttaaagttg tttcttggta tgataatgaa
    20341 atgtcttata cttctcaatt aataagaact ttaggatact ttgcacaatt agcaaaatag
    20401 tcagttttga gaaaatagaa aagtagattg acaaagtccg agtttgtagt ttaatactac
    20461 ggactcagga ctttttttaa gaaaaaatat ataaaataca cctaaataat gttacatact
    20521 atatataaaa atatgataat atgatatatt taatagggta aaagtatgta ctatattata
    20581 cttggcaata aaaaattact ttattaaaag gagagatatt tatgtcaatg cttaacaaaa
    20641 aaactataga agatattgat gtgtgcggaa aaaaagtatt agtaagatgt gactttaatg
    20701 tgccattaca agatggtgta attactgatg aaaatagatt gaacggagct ttaccaacta
    20761 ttcaatattt aatttctaaa ggtgcgaaag ttatattatg ctctcactta ggaaagccaa
    20821 aaggagaagc taagccagaa ttatctttag caccagtagc aaagagatta tctgagatgt
    20881 taggaaaaga agttgtattt gcagcagacg ataatgttgt aggagaaaat gcaaagaaag
    20941 caactgaaaa aatggaaaac ggagatgtag tattattaga aaatactaga tatagaaaag
    21001 aagaaactaa aaacgaagag aatttctcta aagaattagc atcacttgct gaaatatttg
    21061 taaatgatgc gtttggaact gctcatagag cacattgctc aacagttggt gcaggtgagt
    21121 tcttacaaga gagagtttgt ggatacttaa ttcaaaaaga attaaaattc ttaggagaag
    21181 ctgttgcaaa ccctgtaaga ccatttacag ctatacttgg aggagctaaa gtttctgata
    21241 aattagctgt tataaacgaa ttattagaaa aagttgataa tctaataata ggtggaggaa
    21301 tggcttatac attcttaaaa gctcagggtt atgaagtagg aacttcttta cttgaaatag
    21361 ataaagttga atatgctaaa gaaatgatgg aaaaagctaa gaataagggt gttaacttat
    21421 tattaccagt agacgttgtt atggcagacc actttgcacc agatgctact ccaatagtaa
    21481 cagaagatgc taatgtaaaa gaagattaca tgggactaga tatgggacct aagactatag
    21541 caaactttgt aaaaactata aaagaatcaa aaactgtagt atggaatggg ccaatgggag
    21601 tatttgaatt tgaaaacttt gcaaatggta cattatcagt agctagagct atggcagagt
    21661 tgactgatgc aactactgta attggcggtg gagatagtgc agcagcagtt aatcaattag
    21721 gatttggtga caagatgact cacgtatcaa caggtggagg agcatcacta gaatttttag
    21781 aaggtaaaga attaccaggt attgcagcat tagataataa ataaactaat atatagagga
    21841 gattgtaaaa tgagaaaacc tataattgca ggaaactgga aaatgcataa aacaataaaa
    21901 gaagctttag aatttgtaaa tgaagttaaa gataaagtaa attctgataa agtagaagct
    21961 gttatatgtg caccatttac tttattaaag gatttaaaag aagctactaa gggtacaaat
    22021 ataaagatag gtgctcaaaa tatgcacttt gaagaaaaag gagcatttac aggagaagtt
    22081 tcacctctta tgttaaaaga aatagatatg gactatgttg taataggaca ttcagaaaga
    22141 agacaatact tcaatgaaac tgatgaaact gtaaacaaga aagttttaaa agcattagaa
    22201 gtaggaatag acccaatatt atgtgttgga gaaactttag aacaaagaga agctggaaaa
    22261 actaaagatg tttgtaaagt tcaagttgaa aaagctttag aaaatgttct taaagatgat
    22321 ttagcaaaag tagttgttgc atatgagcca atctgggcta ttggaactgg taaaactgca
    22381 actgctgaag atgctaatga cgttatatct tatataagag aagttataaa aggattatat
    22441 ggagaattag ctaatgaagt tagaatacaa tacggtggaa gtgttaaacc ttcaaatgta
    22501 gccgaaataa tgggtcaaag tgatatagat ggagctttag taggtggagc tagtttagct
    22561 agtaatgatt acctagacct tgttaatttc taaggagtga aatgatgaaa aaaccagttg
    22621 ctttaattat tatggacggg tttggataca ataaggatgt taagggaaat gcaattgctg
    22681 agtccaaaac tcctaattta gatagaataa aaaaagagta tccaaacaca ttgataaatg
    22741 ctagtggtct tgatgttggt ctacctgatg gtcaaatggg aaattcagaa gttggacaca
    22801 ctaacatagg tgcaggtaga atagtatatc aagatttaac tagaataaca aaatctataa
    22861 aagatggtga cttttttact aataaagttt tatgtgaagc aatggataat gcaaaagaaa
    22921 attctcttca tgtaatggga cttttgtctg atggaggagt acattcacat atagaccatc
    22981 ttaaggctat aatcaaaatg gcaaaagata aaggcgtaca aaaggtgtat gttcacgcat
    23041 ttactgatgg tagagatact gaccctcaaa gtgcattaga atatgccaaa gaagtacaag
    23101 ctagtatgga tgaaattgga gtaggtgaat ttgctacagt ttctggtaga tactacgcta
    23161 tggatagaga taagagatgg gaaagagtag aacttgcata caatgccatg gttagaggta
    23221 ttggtgaaaa agcaaattct attgaggaag ctattcaaaa ctcttatgat gatggaaaaa
    23281 atgatgagtt tataatgcca acagttatta tgaaagatga taaaccagtt ggaagtataa
    23341 aggaaaatga ttcaattata ttcttcaact ttagaccaga tagagctaga caaataacta
    23401 gagctttagt ttgtgaagag tttgatggat ttaaaagaga agatattaaa aacttctttg
    23461 tatgcttaac agagtacgat ataactatag agaatgtgca tatagcattt ggacctcaat
    23521 ctttagccaa cactctaggt gagtatctag ctaaaaatgg aaaaactcaa cttagagctg
    23581 ctgaaactga aaagtatgca catgtaactt tcttcttcaa tggtggagta gaagagccaa
    23641 ataaaggtga agaaagacta ttgatacctt ctccaaaggt tgcaacttat gatttaaaac
    23701 cagaaatgtc agcatatgaa ttgacagata aagctttaga taaattagga gaagataagt
    23761 ttgactttat agtattaaac tttgcaaatc ctgatatggt aggtcataca ggaagtatag
    23821 aagcggctat aaaggctgtt gaaactgtag atacttgtgt aggaagattg atagataaaa
    23881 tagtagagtt aggtggaagt gcaataataa ctgctgacca cggaaatgct gaatatatgt
    23941 tagacccaga aacaggaaaa actgtaacgg ctcactctat taatccagta ccatttattg
    24001 tagttggtca agaatatgaa agtgcaaaat tattggatgg aggaagatta tctgatatag
    24061 caccgactgt tttagatatg atgaagttag aaaagccaga agaaatgact ggtcattcac
    24121 ttatttcaaa atagtcgatt ctgataagta gagaataata tataaactac aatataaatt
    24181 taaaaataat gcagtttagg tttattttgt aaagtttaga ctttatgaca gaagatttag
    24241 attttgtaag ttttggatat tgtaaggtgt agatgaagat atattttata aaatttacaa
    24301 gatagacaat ttataaaata aaaaattata atatagataa taatgtaaat aatgatataa
    24361 ata
//
LOCUS       DAJMZY010000058        24273 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.058, whole genome shotgun sequence.
ACCESSION   DAJMZY010000058 DAJMZY010000000
VERSION     DAJMZY010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 24273)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24273)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24273
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.058"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            47..784
                     /gene="cas6"
                     /locus_tag="OE968_002218"
     CDS             47..784
                     /gene="cas6"
                     /locus_tag="OE968_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endoribonuclease Cas6"
                     /protein_id="HCP7219495.1"
                     /translation="MSRISIFMESCNGKFPNENSMLSVSFIKNILNAENKDFAKNIFN
                     YGEERKNNKQIKDINTAIYIPNLIRSKNELLVDGDIIFNISFYNYSMFSKLYNGILKV
                     KELEYKGYRFKIKNIKIHKEHEIKENGVIFKTMSPIIVKNKEGKYLDVEDSNYIECLN
                     YIANLTLESIRGSGLRKPLEFIPLNFKKRVLKEKIRGFKEREFYYINAYAGTFFLKGN
                     MEDLNALYKMGIGYRRTENAGMVDILK"
     gene            789..2264
                     /locus_tag="OE968_002219"
     CDS             789..2264
                     /locus_tag="OE968_002219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219496.1"
                     /translation="MREIKAKFYRSGDIVRDIGIVYFCELLMDLKNELEKNDYKLKFT
                     CELNRNYLSLESAEYIDPKYISDYILENQLFKVFKNGKKETLEKIFSNIDNLTYVNFI
                     EELDKSSATEKQKEGIKKDFKNRRFPYVRNSGKYGLNTSLENMEKNVKRIVDIVIKSN
                     IEIDEIDKLDLKQYEEKDSVCNVCNINKTTKLDIDLRERKDSKYNFLFRGAEKSGFKR
                     SGQVESNICFECEFFNLMCLLYINLKRPMVFAYTNDLRELAFLNHKIMLKRKMYSDKS
                     FYKKLLHEKISSIRLYRIDIDTNKGIILKFDSIIEYKELLKKIELIDIIDNYNFSREP
                     MNTRNLGKKMINNGNLSNLKELLLDNISVLRQLTGTSREMDFVSSSYNIGLYIKLCWI
                     VDGREEYKMKNYIESNLIYSRVGKDLFNKMTDESRRKNFSMKVIQLLKSNDRTQLFQT
                     IMHVLVSNGILIGEGFVEGLMQSSELELNTNVGLFIQEIMK"
     gene            2284..3300
                     /gene="cas7i"
                     /locus_tag="OE968_002220"
     CDS             2284..3300
                     /gene="cas7i"
                     /locus_tag="OE968_002220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated protein
                     Cas7/Cst2/DevR"
                     /protein_id="HCP7219497.1"
                     /translation="MNEKRVKGVTLTILTESPVPLSYDQGYGNYTPIKKEQYRDKVHA
                     KTSIATITYDLRRILHQEYGWNLSNIVFGKKGNIYPSIKKNVGCVDENGLETDVFGYL
                     IPLKEKGSISKASPLRIIPFRSLNSYRGSTQLITNRGFLSSEFGRKYYDEREENEVLR
                     DENFPTTQALAIEETLSDYYVYTITLELDRIGVVEVEEDGKLLLPEERKFMSKELREK
                     AVKDILDAITVFTRNIKHSSVLLKPLAVMGGAFDKVVPFFWDDVDYNADSGEINLEGV
                     IETIESYSLKESNTILAINDRLKISNKKELNKFNLSKYPVKEIKNLADRLEIGEDNMW
                     YLKE"
     gene            3316..4113
                     /gene="cas5"
                     /locus_tag="OE968_002221"
     CDS             3316..4113
                     /gene="cas5"
                     /locus_tag="OE968_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated protein Cas5"
                     /protein_id="HCP7219498.1"
                     /translation="MKVLQCKLKQPTAHYRDPKVFQNEYISTLNLPSKTTIMGMITYL
                     CDRRLNSDIDIGIIGTHHHRELEFSRGENIDFWNEYTNMRKGKDKEKFLLQGNYYDYY
                     KEHKAQNSILNYEVLKEVELTIFISCKDDEELEFIRKKLESPCKYANLGRKEDFVIPS
                     EKGCFVKEVELKEVIPMNTRDAIKENIKLKNTYVRVDLRDKENVETIINQGVLIALPY
                     KYKDLEANRDDRVYEFCHYIYVDNDGIYPKNIKVNVCIDTKEVFTWL"
     gene            4140..6548
                     /locus_tag="OE968_002222"
     CDS             4140..6548
                     /locus_tag="OE968_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated helicase/endonuclease Cas3"
                     /protein_id="HCP7219499.1"
                     /translation="MKNIMQKEILAKSYNLRTNQQEQTLVEHIKDLFEVLESILELNL
                     YSDKDVEILKICCALHDLGKINSIMQQKMEINNKISYSCSEEERKKLESDKKSLKKIA
                     RHNIFSGAFLKDILEKMNLSEEDKLYIYKSIMLHHGNYEDYMRLSISKVQEEIYEYIE
                     KGILEKEEFNLKDIESYINSILNVDFKFGEDVLDYDYIDKLSESMFIDSDYNNGQIDD
                     SVLNYRKFKYILYKGMLNLIDHSASSRQKGIKFYNDFTDEEIDNMILNEIYKSQGNLE
                     KNNIEFNTIQKRLRELSGRNVLTVAFTGSGKTAADYRKTFKRKFFLVPNKISAESFYR
                     KNIFQNKNDLDTRSSNDYIGLLHGDINLYSENEDNGEHDFVLTLRDIDLSINFCKPCV
                     IATVDQLLLSMFKFPGYEKIFAAVKNASITVDEVHLLEPKMFLILIYFMQFACKYLDV
                     DFHLMTATLPKSYKEQMINKGIIFQEESNENVTDKGEIVFIESNKEEEICEGKDVKVS
                     FIKEKEIKSIVEDALENKQKILIIKNTIDSVNRTYEFLKENLSDKYGGVDIDVLHSRF
                     KFKDKKEKYSKILNGEGDIWISTQSVEISLDLDFNIIISDLATMDSLIQRMGRCNRNN
                     KYEYGNFYILPSEDKIYDNKLKNTTKNILKDILKTNSIFTMGIRKTILDDYYDNSVVK
                     KYFEENFISCDKEIKNIYGINKEIFDGLDLIFNFEPYKNIVDSKKEAAKIFRDVDVSY
                     KIILEEDFYKEDRELQQDSIQVSGFIFNRLYYYGLISKVEGYMVLKSSSKFEYNSTVG
                     LILK"
     gene            6990..7937
                     /gene="prmA"
                     /locus_tag="OE968_002223"
     CDS             6990..7937
                     /gene="prmA"
                     /locus_tag="OE968_002223"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HCP7219500.1"
                     /translation="MNNWIEVTIKTTTEAVEPITNILYEQGAGGAVIEDPKDFLFQKK
                     NELDWDYVEEEVFKKNEEDDVLIKTYVSEEKNVMEFVEIIKQKVLGLKDFGIDIGEGS
                     VSLDQVNEADWANAWKAYYKPTKVGQRVVVKPTWEDYAMQEGDLIIELDPGMAFGTGT
                     HETTSMCIRELEKYVNKDSKVFDIGCGSGILAIAAAKLGAKEVVAVDLDEVAVKVAKE
                     NVLENKVEKSVSVMHGNLTDVIKDKADVIVANIIADIIKILAKDVQNFMKEDAIFISS
                     GIILDKVEEVKESLIENGFEIVEVQKLGEWSAIVSKLKK"
     gene            7956..8714
                     /locus_tag="OE968_002224"
     CDS             7956..8714
                     /locus_tag="OE968_002224"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HCP7219501.1"
                     /translation="MDRFFVEKNNINLQDKTCTIEGEDVKHISKVLRCKLGEKLEICD
                     KNNNEYICEIMNIDKSIVNLEILEKVDINRESELKVRLYQGLPKAPKMEMILQKLTEV
                     GVEEIILVQTKRSVVKVDDKKEDKKFERWERIIYEAAKQSKRGKIPKLRGVLSFKEAL
                     EDMKKNNVNICPYENERTVSIKHALKKCDSNIDSVGIFIGPEGGFSEEEIEQIQKNNC
                     NVVSLGPRILRTETASVVASTIALYELSDLGGEK"
     gene            8716..10014
                     /gene="mtaB"
                     /locus_tag="OE968_002225"
     CDS             8716..10014
                     /gene="mtaB"
                     /locus_tag="OE968_002225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-
                     methylthiotransferase MtaB"
                     /protein_id="HCP7219502.1"
                     /translation="MKKVAFYTLGCKVNQYETEAMLELFEKDGYEQVNSEEYADVYVI
                     NTCTVTHMSDRKSRQYIRRVKKKNPDAIIAVVGCYSQVSPEEILDIEEVNLVMGTNDR
                     RKIVEEIKKINSSKKVSTVDDIMKVKAFEEIEISQTNGKTRAFMKIQDGCDRFCTYCI
                     IPYARGRVRSRDIDSIVDEVKKLANNGYKEVVLTGIHVASYGKDLKDRDIKLLDVIKQ
                     INQIEKIERIRLSSVEPILFTDEFVNEVLKMDKVCPHYHLSLQSGCDETLKRMNRRYT
                     TLEYKTIVDRLRSKMPDVAITTDVIVGFPGETNEEFKKTYEFLKEIELSQMHIFKYSP
                     RKGTPAATMENQVDPQMKHFRSEQLLNLSKVNFNKFATKFIGRELDVLFEQNIEGNKY
                     EGLTSNYIRVVVESDKNIQGQILKVKINDVKDEYVEGILL"
     gene            10057..10407
                     /locus_tag="OE968_002226"
     CDS             10057..10407
                     /locus_tag="OE968_002226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine triad nucleotide-binding protein"
                     /protein_id="HCP7219503.1"
                     /translation="MDCIFCKIANGEIPSTKVYEDDRVLAFNDLNPVAPYHILVVPKK
                     HYDSLIDIPDKEMDIVSHIHVVINKIAKEKGFDQTGFRVINNCGSDGGQEVKHLHYHI
                     LAGKKLPNYEAGQN"
     gene            10570..10749
                     /locus_tag="OE968_002227"
     CDS             10570..10749
                     /locus_tag="OE968_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HCP7219504.1"
                     /translation="MSEVRVRENETLDSALRRFKRQCAMSGIMSEVRKREHYDKPSVK
                     RKKKAEAARRKNAKK"
     gene            10779..11222
                     /locus_tag="OE968_002228"
     CDS             10779..11222
                     /locus_tag="OE968_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HCP7219505.1"
                     /translation="MSLKQKLQEDLKSSMKNKDTVRKSVVTLIRASIKQYEVDNRVEL
                     DEDGIIDVIAKQLKQRRDALVEFEKAGREDLIKETEGEIEVLKEYLPQQLSEEELEEI
                     VKSTISEVGATSMKDMGKIMSVIQPKVKGRADGKLINKLVKQNLQ"
     gene            11333..11830
                     /locus_tag="OE968_002229"
     CDS             11333..11830
                     /locus_tag="OE968_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan-rich sensory protein"
                     /protein_id="HCP7219506.1"
                     /translation="MIISVKEIRNFLINIFIPLIIGYLSSILTMIISGTDISTYYLQL
                     TKPSFAPPAFIFPIVWTILYILMGISSYLILRKGYNLPKVRDAIFYYGLQLVLNFIWS
                     ILFFGFGLRFTALIDIIIMILVSIIMISKFSKIDKRSGYINLIYLMWLVYAGFLNYFI
                     WFINK"
     gene            12023..12586
                     /gene="raiA"
                     /locus_tag="OE968_002230"
     CDS             12023..12586
                     /gene="raiA"
                     /locus_tag="OE968_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HCP7219507.1"
                     /translation="MQIIVSGRQMKLTDGIKGYVDGKLSRLEKYLDPESEVKVTVSAK
                     KDRQKVEVTIIPINGQIIRAEDVEDDLYAAIDIVCDKLSRQVVKYKTKVKDKVQNNKS
                     IRFENLDFIDNSSEFDDYDYDDEEDENIVIERRKKFNVKPMSSEEAILQMELVGHNFY
                     MFRNQDNFEINIVYKRKAGGYGLIEQD"
     gene            12799..13035
                     /locus_tag="OE968_002231"
     CDS             12799..13035
                     /locus_tag="OE968_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YabP/YqfC family sporulation protein"
                     /protein_id="HCP7219508.1"
                     /translation="MLEISTDLQVNQPVITVTSNTFISIENYLSILEYEVDLIRIKTK
                     VKTIKISGDKLSLKYITDSEIGIKGIIYNVEYVD"
     gene            13048..14391
                     /gene="yqfD"
                     /locus_tag="OE968_002232"
     CDS             13048..14391
                     /gene="yqfD"
                     /locus_tag="OE968_002232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein YqfD"
                     /protein_id="HCP7219509.1"
                     /translation="MISFIRGYYVIVVEGVGLEQFLNHLIRNGISVYNVTRIKNTKME
                     FHIDRQDIKEFKNVYRGSKFDIKVKQKTGVPFIIKRVYKHKGMWICALVSLFLLMSTS
                     QFVTDVYIQSPEGIKKEALRNELYKVGVRPGVYKKSIDRKEVRDHMMSKFNDVAYLSI
                     NVKGTNIFVTVTKKAESLKSTDQSNYCNVIALKNGIIEKVIPRSGKSVIKSGDIVQKG
                     DVLLNGANTKSIPEVWASTFYESTKKASYVDTVNKKTGEKKNIYTLSFYDKEFTMRKN
                     IKYKDYVVENKEKKLSIGNYTFPIKIKTSTFYETKKVEVKRNKEELKKELSEKALKEL
                     EYIIPASARIIDVKHNFKVNKNMLEYLITVQTSENIAKIYPLSKSEAERFIKEESKPD
                     EGEEEVPSNPEKRPLNDIRNEFDEDNKDNKDQNNSDENNSNQNSNNSQNNNSNNN"
     gene            14330..15445
                     /locus_tag="OE968_002233"
     CDS             14330..15445
                     /locus_tag="OE968_002233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HCP7219510.1"
                     /translation="MKIIVIKIVIIVKIIIAITTNKIKLKILGGLIQLIIQKKFTIAD
                     GNFERELFGNFDENVKLIEKTLNIDVILREGNIILIGEEKNVDSALKLMNELHQTVSN
                     GKHLDKQSISYSLSLLLEGSEQKIKELEGTIVITQRGKAVQPKTLGQKEYIKLIENND
                     ITFGVGPAGTGKTYLAVAMAVKAFKRDEVSRIILTRPAVEAGESLGFLPGDLKDKVDP
                     YLRPLYDALFEMLGADKFNKYLERGTIEVAPLAFMRGRTLDNSFIILDEAQNTTSEQM
                     KMFLTRLGFGSKAVVTGDVTQTDLPQNKKSGLIQATEILKGVPGIGSIMLTDRDVVRH
                     ELVQRIIRAYEKHDKREEFKKEERKKAKMQEKTFKRK"
     gene            15502..15963
                     /gene="ybeY"
                     /locus_tag="OE968_002234"
     CDS             15502..15963
                     /gene="ybeY"
                     /locus_tag="OE968_002234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HCP7219511.1"
                     /translation="MDLILDDRQDKLEVSEELIEKIKDIIIECLDYEGYDDNYEVSLS
                     FVDNKEIHELNREYRGVDRVTDVLSFPLLSDDFEDVELEEESLGDIVVSLERALEQSI
                     EYNHSFEREVCFLICHSMFHLLGYDHDTDENTKEMREKEEHILNKLNITRE"
     gene            15969..16688
                     /locus_tag="OE968_002235"
     CDS             15969..16688
                     /locus_tag="OE968_002235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HCP7219512.1"
                     /translation="MKPEKTRQGIIKAFNAAIEGILYTFKFERNMKIHYLGSVAVLII
                     SLFFNFSKLEMIMLLMSICLVVVAEMFNTAIEKAVDLVTDEYHVLAKIAKDVAAGGVL
                     VAALNSVVVGYILFYDKLTDISGILIYKIRESELHITLICILLVLIAVVVVKALTSTG
                     TPLKGGMPSGHAALAFAIATAITLMTERVVASTLAYIMAVLVAQSRIEGKIHTFWETI
                     AGALLGVLIAILVFQLGMFYN"
     gene            16807..17208
                     /locus_tag="OE968_002236"
     CDS             16807..17208
                     /locus_tag="OE968_002236"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HCP7219513.1"
                     /translation="MDNIELLRLAEDARQHSYAPYSGFRVGAALLTKSGKVYTGCNIE
                     CASLGGTNCAERTAIFKAISEGDKDIYKIAIASDNSENNEQTYPCGICRQVIIEFGSD
                     IKIITGYTKGEVFEHSIKDLLPNYFSGNDLK"
     gene            17272..18165
                     /gene="era"
                     /locus_tag="OE968_002237"
     CDS             17272..18165
                     /gene="era"
                     /locus_tag="OE968_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HCP7219514.1"
                     /translation="MFKSGFVSIVGRPNVGKSTLMNNVVGEKIAIMSDKPQTTRNTIQ
                     AVYTDEEMQIVFLDTPGIHKPKNKLGEFMVKAATEAFKNVDLILFVVDDSKKIGPGDR
                     KIIEDLRSVKTPIILVVNKIDQLDQKDELFDIIKMYDREGIFKEIVPISALKGKNTDT
                     LIKVIQNYLEEGPKYFPDYMITDQPERVLIAELIREKVLHYLNDEIPHGVAVEIEKMK
                     ARNDKEIVDVSAVIYCERDSHKGIIIGKNGRKLKGIGKSARQDIELLLGSQINLQLWV
                     KVKENWRNLQNYINNFGYNDK"
     gene            18177..19556
                     /gene="mgtE"
                     /locus_tag="OE968_002238"
     CDS             18177..19556
                     /gene="mgtE"
                     /locus_tag="OE968_002238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HCP7219515.1"
                     /translation="MDRKLDASQDLLYEVKSLIDNNKVLELRELIEEYHIIDIFDIME
                     NLEEDMKIQLFEVLPLDMASSILEEGSVEFFISILSKLDVEHSKNILELMSLGDMADK
                     LSELEEEEREHIINLLNQENADYVKELLFYDEDSAGGTMTTGYISINKDMTALEAIDH
                     MREEAEEAETIYYIYVVDDEEKLVGVLSLRELIIARDANIVEDLMSENIISVYVDEDR
                     EEAVRLVSKYNLIAIPVVDRQEKLKGIITVDDIIDVMEEEATEDMYKFAGSSEHEREV
                     AEKENPTLREQIISALRGRLPWLIITLVGGLLASLILSNLDYIMNPVYAPLVFFIPVV
                     IGMGGNIGTQSSSVTVITLSNKDLNFSNVVREGIVGIITGLLCSIITGIVIYFVMRKL
                     DIVLIVSISLFINMVLGATIGAFMPVLLKKMDADPSTVSSPIISTALDITGIAVYFII
                     TTALLSKIV"
     gene            19629..19784
                     /locus_tag="OE968_002239"
     CDS             19629..19784
                     /locus_tag="OE968_002239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqzL family protein"
                     /protein_id="HCP7219516.1"
                     /translation="MNNISWEVFKKTGSIDAYLYFCDCKNIHEEIEEVREKKEDDDNP
                     EHPGDST"
     gene            19750..20523
                     /gene="recO"
                     /locus_tag="OE968_002240"
     CDS             19750..20523
                     /gene="recO"
                     /locus_tag="OE968_002240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HCP7219517.1"
                     /translation="MIILNTQGIVLKAIRYKESDIILTLFTRKLGKVSAIAKGAKKNK
                     SSLLSSSQLFSYSNFTLKKQGNMYKVTQSEIIKSFYNISYDIEAFSYATYITKLVENS
                     ILENQTNNRLFILLAQTLYLYTQDNTDNRFITAAFELKFLDYIGFKPIVNKCINCECK
                     ILQNSVFNIYEGGILCSKCSKLFDNNIKLDLTTISLMEYVLRNDILTCSKAKVSKYIT
                     HELENILDKYLKVYVDNINFKSLHVLQSVKNNKGVDNDE"
     gene            20516..21115
                     /locus_tag="OE968_002241"
     CDS             20516..21115
                     /locus_tag="OE968_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4342 domain-containing protein"
                     /protein_id="HCP7219518.1"
                     /translation="MSSNITIEMVDSVFERVPGATYAEAKEALVMCNGDVIEAVIYLE
                     NKKNTCNCKAKSAKETMEEVFGKDGENIKFQLKELLRKSSVVRIIVEKDGKTMMNIPL
                     TVGVVGLAFVPLATLVGLSAAVISKYRIKVQNEEDGEIVDLGELNEEKLHVLKNMITN
                     AAKDVKDVVVDKKEDDKDVTADLMKEESEKNKEDEDENK"
     gene            21275..22153
                     /gene="glyQ"
                     /locus_tag="OE968_002242"
     CDS             21275..22153
                     /gene="glyQ"
                     /locus_tag="OE968_002242"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HCP7219519.1"
                     /translation="MNFQEMILALQKYWSKQGCIMMQPYDIEKGAGTMNPNTFLRSLG
                     PEPWQVCYVEPSRRPADGRYGENPNRLYQHHQFQVILKPSPDNIQELYLESLKEIGID
                     PSEHDIRFVEDNWEAATVGAWGLGWEVWLDGMEITQFTYFQQVGNIECELETGEITYG
                     LERLAMYIQEVDSVYDLKWNDKITYGEVFNKAEYENSMYAFELCDADMLFNLFDIYEK
                     EALRLMENGLVIPSYDYVLKCSHAFNTLDARGAIGVSQRASFIGRVRNMAKTVAETFV
                     KQREEMGFPLLKDGDK"
     gene            22153..24219
                     /locus_tag="OE968_002243"
     CDS             22153..24219
                     /locus_tag="OE968_002243"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HCP7219520.1"
                     /translation="MKNYLLFEIGVEEMPSRFVGSTLEQLKNNLSKLFDENRIAFDKI
                     NAYGTPRRLTLVVEGLSDRQSDLEEEIKGPAKKIAVDAENNLTKPALGFIKSKGLSES
                     DIYFKQVGKEEYIFATIKQDGKETSEVLKDILPETIKSVVFPKAMRWGGKNLKFARPI
                     RWIVALLNDKVLEFDLEGIISSNVTKGHRFLGESTIEVDSIEDYFEKLEKNYIVLDQN
                     KRKEMIRKQCIEVANSLGGEVEFDEDLLEEVTYLVEYPTAFYGEFDVDYIKLPKEVVI
                     TPMKQHQRYFPVLKEGKLLPNFIAVRNGDSYRIDNVKAGNEKVLEARLADALFFYRED
                     TKRNLESYIEKLKTVVFQVKLGTIYDKTLRLEKLSADILDSLGLVDEKADTIRAAKLS
                     KADLVTGMVGEFDELQGFMGKEYAKVGGENDVVSEAIFEHYLPRFAGDILPKTNAGVA
                     LSIADKLDSIAGFFAIGIQPTGSQDPYALRRQALGILSILMDRKVAVDIKILIEHALD
                     NYSELDFNKEEVVEQIMNFFNERVKNLFKDLGIRYDVVDAVLSSDINDVSDMHMRALE
                     LNNWLEKDELVEMLTAFNRVSTLAQKAESDKIDESLLKEDAEIKLYNEFKQVKVKVNE
                     LLKDKKYGIALDEFASLRPVVDNLFDTVMVMDNDEAIKNNRLALLKQVYDTMLGICDL
                     SKIVYK"
BASE COUNT        10049 a         2283 c         4508 g         7433 t
ORIGIN      
        1 acaaatagag aataatgaat tatactagaa agtaggaggt gaaaatatga gcagaatttc
       61 aatttttatg gaatcatgta atggcaaatt tccaaatgaa aattcaatgt tgtcagtttc
      121 ctttataaaa aatattttaa atgcagaaaa caaagatttt gctaaaaaca tatttaacta
      181 tggggaagaa agaaaaaaca ataagcaaat aaaggatata aatacagcca tttacatacc
      241 aaatcttata agaagcaaaa atgagttact tgttgatgga gatataatat tcaatataag
      301 tttttataat tattctatgt tcagtaaatt atacaatgga attttaaaag taaaggagct
      361 agaatataaa ggttatagat ttaaaataaa aaatataaaa atacataaag aacacgagat
      421 aaaagaaaat ggtgttatat ttaaaactat gtctcctata atagtaaaga ataaagaagg
      481 taaatattta gatgtagaag attcaaatta tatagaatgt ttaaactata tagctaatct
      541 aactctggag agtataagag gtagtgggct tagaaagcca ttggaattta tacctcttaa
      601 cttcaaaaaa agagtgttaa aagaaaagat tcgtggattt aaagagagag aattttacta
      661 tataaatgct tatgcaggaa catttttttt aaaaggaaat atggaagatt taaatgcact
      721 gtataaaatg ggaattggat atagaaggac ggaaaatgca ggaatggttg atatattaaa
      781 gtagcgaggt gagagaaata aaagctaaat tttatagatc aggtgatatt gtaagagata
      841 ttggcattgt ttacttttgt gaattactaa tggatttaaa aaacgaacta gaaaaaaatg
      901 attataagct aaaatttact tgtgagttga atagaaatta tttatcttta gaatctgcag
      961 aatatataga ccctaagtat atatctgatt atatattaga aaatcaactt tttaaggtat
     1021 ttaaaaatgg gaaaaaggaa accttagaaa aaatatttag taatatagat aatttaacat
     1081 atgtaaattt tattgaagaa ttggataaat cttctgcaac tgagaaacaa aaggaaggga
     1141 ttaaaaaaga ttttaaaaac agaagatttc catatgttag aaatagtggt aagtatggat
     1201 taaacacgag tctagaaaat atggaaaaaa atgtaaaaag aatagtcgat attgtgatta
     1261 aatcaaatat agagatagat gaaatagata aacttgattt gaaacaatat gaagaaaaag
     1321 atagtgtatg taatgtttgc aatataaata aaacaacaaa actagatatt gatttaagag
     1381 aacgaaagga ctctaagtat aactttttat ttagaggtgc agaaaaatca ggttttaaaa
     1441 gaagtggaca agttgaaagt aatatttgtt ttgagtgtga atttttcaac ttaatgtgtc
     1501 ttttatatat aaatttaaaa agaccaatgg tttttgcata tacgaatgat ttaagagaat
     1561 tagcattttt aaatcataag ataatgctta aaagaaaaat gtattcagat aaatcatttt
     1621 ataaaaaact tttgcatgaa aaaataagtt caattagact atataggatt gatattgata
     1681 cgaataaagg tataattcta aaatttgact ctattataga gtataaagaa ttattaaaaa
     1741 aaattgaact tatagatatt atagataatt ataatttttc aagagagcca atgaatacta
     1801 gaaatttggg taaaaaaatg attaataatg ggaatttatc aaatttaaaa gaattattac
     1861 ttgataatat aagtgtttta aggcaactaa ctggaacttc tcgagaaatg gattttgtat
     1921 ctagttcata taatatcggt ttatatataa aattgtgttg gattgtagat ggaagggagg
     1981 agtataaaat gaaaaactat atagaaagta atttaatata ttcaagagta ggtaaagact
     2041 tatttaataa aatgacagat gaatccagaa gaaaaaattt ttctatgaaa gtgattcaac
     2101 tacttaagtc taatgataga actcagctat ttcaaactat aatgcatgtg ttagtttcta
     2161 atggaatctt aataggagaa gggtttgtag aaggtctaat gcagagttct gaattagaat
     2221 taaatacgaa tgtaggtcta tttattcaag aaatcatgaa ataaaaaagg gggaaaattt
     2281 aaaatgaatg aaaaaagagt aaaaggagta acattaacta tactgacaga aagcccagtt
     2341 ccactttcgt atgaccaagg gtatggaaat tatacaccaa taaaaaaaga acaatataga
     2401 gataaagtac atgcaaaaac tagtatagct acaataacat atgatttaag aagaatactc
     2461 catcaagaat atggttggaa tttaagtaat attgtttttg gaaaaaaagg aaatatatat
     2521 ccatctatta agaaaaatgt aggatgtgta gatgaaaatg gattagagac tgatgtattt
     2581 ggttatttaa taccacttaa agagaaaggt tctataagta aggcttctcc gcttagaata
     2641 atacctttta ggtcactaaa ttcatataga ggttcaacac agttgataac aaatagaggt
     2701 tttttaagta gcgaatttgg tagaaaatat tatgatgaga gggaagaaaa tgaagtactt
     2761 agagatgaaa actttccaac aacacaagca ttagcaatag aagagacttt atcagattac
     2821 tacgtttata caataacatt ggagcttgat agaataggag tagtagaagt agaagaagat
     2881 ggaaagttac ttttaccaga agaaagaaaa tttatgagta aggagttaag agaaaaagca
     2941 gtaaaagata tattagatgc aattactgtg tttacaagaa acataaaaca ttcatcagta
     3001 ctattaaaac cacttgcagt aatgggtgga gcttttgata aagttgtacc atttttttgg
     3061 gatgatgtag attataatgc tgatagtggt gagataaatt tagagggagt catagaaact
     3121 atagaaagtt atagccttaa agaaagtaac acaatacttg ctatcaatga cagattaaaa
     3181 atttctaata aaaaggaatt aaataagttt aatttaagta aataccctgt aaaagagatt
     3241 aaaaatctag cagatagatt ggaaattgga gaagataata tgtggtattt aaaagagtag
     3301 gaggtttttt gaattatgaa agtattacaa tgtaaactta agcaaccaac tgctcactat
     3361 agagacccaa aagtatttca aaatgaatat ataagtactt taaatttacc atctaagacc
     3421 acaataatgg gaatgataac gtatttatgt gatagaagat taaactctga tatagatata
     3481 ggaataattg gaacacatca tcatagagaa ctagaatttt caagaggaga gaacattgat
     3541 ttttggaatg aatatacaaa tatgagaaaa ggcaaagata aagaaaagtt tttgcttcaa
     3601 ggaaactact atgattacta taaagaacat aaagctcaaa atagcatatt aaactatgaa
     3661 gttcttaaag aagtagaact gactatattt atttcttgca aggatgatga agaacttgaa
     3721 tttattagaa aaaagcttga aagtccatgt aaatatgcaa atttaggaag aaaagaagat
     3781 tttgtaatac caagtgaaaa agggtgtttt gtgaaagaag ttgagttaaa agaggttata
     3841 cctatgaata ctcgtgatgc tataaaagaa aatataaaat taaagaatac atatgtaaga
     3901 gttgacttaa gagataaaga gaatgtcgag actataataa atcaaggtgt attgattgca
     3961 ttaccttata aatataaaga tttagaagca aatagagatg atagagttta tgagttttgc
     4021 cattatatat atgttgataa tgatggtata tatcctaaaa atattaaggt aaatgtatgt
     4081 attgatacaa aagaagtttt tacatggctt taaattattt tgaaagatag gtgtttatca
     4141 tgaaaaatat catgcaaaaa gaaatattag ctaagtcata taatttaaga actaatcaac
     4201 aagagcaaac attagttgaa catattaagg atttatttga agtattagaa tctatattag
     4261 aactaaatct atattcagat aaagatgtag agatactaaa aatatgttgt gctttgcacg
     4321 atttaggaaa aattaattca attatgcaac aaaaaatgga gattaataat aaaatatcgt
     4381 atagttgctc agaagaagag aggaaaaagt tagagtctga caaaaaatct ttaaaaaaga
     4441 tagcaagaca taatatattt tctggagcat ttttaaaaga tatattagaa aaaatgaact
     4501 tgtcagaaga agataagtta tatatatata aaagtataat gttacatcat ggaaactatg
     4561 aagattatat gaggttaagt attagtaaag ttcaagaaga aatttatgag tatattgaaa
     4621 aaggcatttt agaaaaagaa gagtttaatc tgaaagatat agaaagttat ataaatagca
     4681 ttttaaatgt agactttaaa tttggtgaag atgtattgga ttatgattac atagataaat
     4741 taagtgaaag tatgtttata gacagtgatt ataacaatgg tcaaatagat gattcagttt
     4801 taaattatag aaagtttaag tatattttat ataaagggat gctgaactta atagaccata
     4861 gtgcatcaag tagacagaaa ggtataaaat tttataacga ttttactgat gaagaaattg
     4921 ataatatgat tttaaatgag atatataaga gtcagggtaa tttggaaaaa aataatatag
     4981 agttcaatac tatacaaaaa aggttgagag aactttctgg aagaaatgtt ctgactgttg
     5041 catttacagg ttcaggaaaa acagctgcag attatagaaa gacttttaaa agaaaattct
     5101 ttttagtgcc aaataaaata tcagcagaaa gtttttatag aaaaaatatt tttcaaaata
     5161 aaaatgattt agatacaaga agtagtaatg attacattgg attacttcat ggagatataa
     5221 acttatattc agagaatgaa gataatggag aacatgattt tgtattgaca ttaagggata
     5281 tagatttgag tataaacttt tgtaaacctt gtgtaattgc aacagttgac cagttattac
     5341 ttagtatgtt taaatttccg ggatatgaaa aaatattcgc agccgtaaaa aatgcatcta
     5401 taactgttga tgaagtacat ttattggaac caaagatgtt tttgattttg atatatttta
     5461 tgcagtttgc atgcaagtac ttagatgttg attttcactt aatgacagct acacttccaa
     5521 aatcatataa agagcaaatg ataaacaagg gaattatttt tcaagaagaa agtaatgaaa
     5581 atgttactga taaaggagaa atagttttta ttgagagcaa caaggaagaa gagatttgtg
     5641 aaggtaaaga tgtaaaggtt tcttttataa aggaaaaaga aatcaagtca atagttgaag
     5701 atgctttaga aaataaacaa aaaattctta taataaagaa tactattgat tcagtcaata
     5761 gaacatatga gtttttaaaa gaaaatttat ctgataagta tggtggtgta gatatagatg
     5821 ttttacatag tagatttaag ttcaaagata aaaaagagaa atatagtaaa atattaaatg
     5881 gagagggtga tatttggata tcaactcaat cagtagaaat atccttggat ttggatttca
     5941 atataataat aagtgattta gcaactatgg atagcttgat acaaagaatg ggtagatgta
     6001 atagaaataa taaatatgaa tatggaaact tttatattct acctagtgaa gataaaattt
     6061 atgataacaa acttaagaac acaactaaaa acatcttaaa ggacatatta aaaactaact
     6121 ctatttttac aatgggaatt agaaaaacta ttttggatga ttactatgat aatagtgtag
     6181 tcaaaaaata ttttgaagag aattttataa gttgtgataa agaaattaag aatatttatg
     6241 gtataaataa agaaattttt gatggattgg atttaatttt taattttgaa ccttacaaaa
     6301 atattgttga tagtaagaag gaagcagcta aaatttttag agatgttgat gttagttaca
     6361 aaattattct ggaagaagat ttttataagg aagatagaga gttacaacaa gattcgattc
     6421 aagtatcagg gtttatattt aatagattat attattatgg gttaataagc aaagtagaag
     6481 gatacatggt actaaaatct agtagtaagt ttgagtataa tagtactgta ggcttaattt
     6541 tgaagtgagc atatgtttaa atataatata cctttagaca ttgaaaatac aaaaagtact
     6601 actgtaagct cactgtaaaa actatttttt taaaaggaaa aataagttgt gagatagagt
     6661 gtttacaagt gtatatagat aataaatttg aggtttaaga ttaactaagt gggtttcagg
     6721 tacatcgcga aaataattat aagttggaga ttttgtatgt ttaagattaa ctaagtggat
     6781 ttcaaatatt gatatagtag atataataga agttttatta ttaggtttaa aattaactaa
     6841 tcggattttt aaatattctg actattatat aaggatatta ttagcttgaa tttaaaacca
     6901 ataatataaa acaacaaaat attatattta tgatataata aaagttatgg aaaaacagga
     6961 atattactat agagaagaga ggtaaactta tgaataattg gatagaagta actataaaaa
     7021 caacaacaga agcagttgaa cctataacga atatactata tgaacaagga gctggaggag
     7081 ctgtaataga agacccaaaa gactttttat tccaaaagaa aaatgaacta gactgggatt
     7141 atgttgaaga agaagtattt aaaaagaatg aagaagatga tgttcttata aaaacttatg
     7201 tttctgaaga aaaaaatgtg atggaatttg tcgaaataat aaagcaaaaa gttttagggt
     7261 taaaagattt tggtatagat ataggtgaag gaagtgtatc attggaccaa gtaaatgaag
     7321 ctgattgggc aaatgcatgg aaagcatact acaaaccaac aaaagtagga caaagggtag
     7381 tagtaaagcc tacatgggaa gattatgcta tgcaagaggg ggatttaatc atagagcttg
     7441 accctggaat ggcatttggt acaggtacac atgagactac tagtatgtgc attagagaat
     7501 tagaaaagta tgtgaataaa gattctaaag tatttgatat tggctgtggt agtggaatcc
     7561 ttgcaatagc agcagctaaa ttaggagcaa aagaagttgt agctgtagat ttagatgaag
     7621 tggctgtaaa agttgcaaaa gaaaatgttc ttgaaaataa agttgaaaaa agtgtatctg
     7681 taatgcatgg taatttaact gatgtaataa aagataaagc ggatgtaata gttgcaaata
     7741 taatagctga tataataaag atacttgcaa aagatgttca aaactttatg aaagaagatg
     7801 ctatattcat atcttcaggt ataattttgg ataaagtaga agaagttaaa gaaagcttaa
     7861 ttgaaaatgg atttgaaata gttgaagttc aaaaattagg tgaatggtca gcaatagttt
     7921 ctaagcttaa aaaataaggg atatggtgac gtataatgga tagatttttt gttgaaaaaa
     7981 ataatataaa tctacaagat aaaacttgca ctatagaagg tgaagatgta aaacatattt
     8041 caaaagtttt aagatgcaaa ttaggtgaga aacttgaaat atgtgacaag aataataatg
     8101 agtatatttg tgagataatg aatatagata agagtatagt taatttagaa attttagaaa
     8161 aagttgatat aaatagagaa tcagaactta aagtaaggct ataccaggga cttccaaaag
     8221 ctccaaaaat ggaaatgata cttcaaaaat taactgaagt gggtgtagaa gaaataatat
     8281 tagttcaaac taagagaagt gttgttaaag ttgatgacaa aaaagaagat aaaaaatttg
     8341 aacgttggga aagaataatt tatgaagcag caaagcaaag caaaagaggt aagataccaa
     8401 aattaagagg tgttttaagt tttaaagaag ctttagaaga tatgaaaaaa aataatgtaa
     8461 atatttgccc ttatgaaaat gaaagaacag tttcaataaa acatgcacta aaaaaatgtg
     8521 attctaatat agatagtgtt ggaattttta taggtccaga aggtggattt tctgaagaag
     8581 aaatagaaca aatacaaaaa aataattgta atgttgtatc attggggcct agaatattaa
     8641 gaactgagac agcttctgtt gtagcatcaa caatagcttt gtatgaacta agtgatttag
     8701 gaggagaaaa ataaattgaa aaaagtagct ttttatacac ttgggtgtaa agttaatcaa
     8761 tatgaaacag aagctatgct agaactattt gagaaagatg gttatgaaca agtcaatagt
     8821 gaagagtatg ctgatgttta tgttataaat acatgtacag ttactcatat gagtgataga
     8881 aaatctcgtc aatatataag acgagttaaa aagaagaatc cagatgcaat aatagccgtt
     8941 gtaggatgtt attctcaggt atctccagaa gaaattttgg atatagaaga agtaaattta
     9001 gtcatgggca caaatgatag aagaaagatt gttgaagaaa ttaaaaagat aaattcaagt
     9061 aagaaagtta gtacagttga tgacataatg aaagttaaag cttttgaaga aatagaaatc
     9121 agccaaacta atggaaagac tagagcattt atgaaaatac aagatggatg tgacagattt
     9181 tgtacttatt gtatcattcc ttatgcccga ggacgcgtta gaagtagaga tattgatagt
     9241 atagtcgatg aagtgaaaaa attggctaat aatggctata aagaggttgt attaacagga
     9301 atacatgttg cctcttatgg aaaagattta aaggataggg atattaaact tcttgatgta
     9361 ataaaacaaa taaaccagat agaaaaaata gaaagaatta ggcttagttc tgttgaacca
     9421 attttattta cagatgaatt tgtaaatgaa gttttaaaga tggataaagt ttgtcctcat
     9481 taccatttat cacttcaaag tggatgtgat gaaactctaa aaagaatgaa tagacgatac
     9541 acaactttag agtacaaaac tattgtagat agattgagaa gtaaaatgcc agatgtggca
     9601 ataactacag atgtaatagt aggttttcct ggagagacaa atgaagagtt taaaaaaacg
     9661 tacgagtttt taaaagaaat agagctttca caaatgcata tttttaaata ttcaccaaga
     9721 aaaggaactc cagctgcaac tatggaaaat caagttgacc ctcaaatgaa acactttaga
     9781 agtgaacaac ttttaaattt aagtaaagta aattttaata aatttgcaac taaatttatc
     9841 ggccgtgagt tggatgtttt atttgaacaa aatatagaag gcaataaata tgagggatta
     9901 acttcaaatt atataagagt tgttgttgaa agtgacaaaa atatacaagg tcagatatta
     9961 aaagtgaaaa taaatgatgt aaaagatgaa tatgtagaag gaattttgct ataacatgta
    10021 gaaattataa tatttataag ataggaggtg gaaagaatgg attgtatttt ttgtaaaata
    10081 gcgaacggag aaataccttc aactaaagtt tatgaagatg atagagtctt agcttttaat
    10141 gacttgaacc cagttgctcc atatcatata ttagttgtac ctaaaaaaca ttatgatagt
    10201 ttaattgata ttcctgataa agagatggac attgtgtcac atattcatgt tgttattaat
    10261 aaaatagcta aagagaaagg ttttgaccaa actggattca gagtcataaa taattgtgga
    10321 agtgatggag ggcaagaagt taaacatttg cactatcata ttttagctgg taaaaagctt
    10381 cctaattacg aagcgggaca aaactaaact aaattattga aaaattgagt tccttcttga
    10441 taaaaatact tgataaaagt aaaaatttag tttataataa acaaagtgtt aggttgtaat
    10501 gcatattatg caaaaagaac atagttacag tcccagcata attgcgctat tggagggagg
    10561 gaaaaagaaa tgtcagaagt aagagttaga gagaatgaaa cattagacag cgctttaaga
    10621 agattcaagc gtcaatgtgc aatgtctggc atcatgtcag aagtgagaaa aagagagcac
    10681 tatgataagc caagcgttaa gcgtaagaaa aaagctgaag cagcaagaag aaaaaacgct
    10741 aagaaatagt agtaaataag aataaagagg tgaaggggat gtcccttaag caaaagttac
    10801 aagaggattt gaaatcttcg atgaaaaaca aagatacagt gagaaaatct gtagtaactt
    10861 taataagagc ttctataaag cagtatgagg ttgataatag ggtcgagctt gatgaagatg
    10921 gaattatcga tgtaatagca aaacaattaa agcaacgtag agatgcatta gttgaatttg
    10981 aaaaagctgg aagagaagac ttaataaaag aaacagaagg tgaaattgaa gttttaaaag
    11041 agtacctacc tcaacaatta agcgaagaag agttagaaga aattgtaaaa tctactatat
    11101 ctgaagtagg ggcaacttct atgaaggata tgggaaaaat aatgtcagtt atccaaccaa
    11161 aagttaaagg aagagctgac ggaaaactta taaataagtt ggtaaaacaa aacttacaat
    11221 agattgatat agcctagaga gaaatctcta ggctttttat agtttttggg aataacgagt
    11281 catatttgag catatctata atcaaagaaa attttgaaag aaggggaaaa atttgattat
    11341 atcagtaaaa gagattagga attttttgat aaacatattt ataccactaa taataggtta
    11401 cttaagtagc atcttaacaa tgattatcag tggaacagat atttcaacct attatttaca
    11461 actcacaaag ccaagctttg caccaccagc ttttatcttt cctatagttt ggactatatt
    11521 gtacatattg atgggtatat cttcatacct aatattaaga aagggttaca acttacctaa
    11581 agtaagagat gcaatttttt attatggatt acaacttgta ttaaacttta tttggagtat
    11641 actatttttt ggatttggac ttagatttac agctttgata gatataataa taatgatttt
    11701 ggtttctata ataatgattt cgaagttttc taaaatagat aagagatctg gatacataaa
    11761 tttgatttat ttaatgtggc ttgtttatgc aggatttttg aactatttta tatggtttat
    11821 taataaatag aatgtaaaga ttttgtaaat taccctgtac ttttaataat atcataacaa
    11881 acgaaaaata aatagactat taaaaataat cattttcata tacaataata ttaatttaaa
    11941 tacaataaat ttataaaaat tgtatttaaa gattaacata ttaaagtatt agaattggaa
    12001 aggcttgaag ggagaggttt ttatgcaaat aatagtatct gggagacaaa tgaaattaac
    12061 tgacggaata aaaggatacg tagatggaaa attaagtagg ttagaaaaat accttgatcc
    12121 tgaatcagaa gtgaaagtaa cagtaagtgc gaaaaaggat agacaaaaag tggaggttac
    12181 aataattcct attaacggtc aaataataag agcagaagac gtagaagatg acttatatgc
    12241 agcaattgat attgtttgtg acaaattaag tagacaagtt gtcaaatata aaactaaagt
    12301 taaagacaaa gttcaaaata ataagagcat aagatttgaa aatcttgact ttatagataa
    12361 tagcagtgaa tttgatgatt atgattatga tgatgaagaa gatgagaata tagtaataga
    12421 aagaagaaag aaatttaatg taaaacctat gagttctgag gaggcgatac ttcaaatgga
    12481 actagtagga cacaatttct atatgtttag aaaccaagat aattttgaaa taaacatagt
    12541 gtataagcgt aaagctggtg gatatggttt aatagaacaa gattaataaa aattgtatac
    12601 gtttagattt tatataagaa aaaataaaaa ggtaatcatg ttgatttttt atcaatatga
    12661 ttaccttttt cttgtttaaa taatatatta gatattaggt atttattata taaaaatttt
    12721 aaaactaatc tgttacaaca tcaataaagt gcataaatac ctatttcaag cataaaatta
    12781 attaaggggg taatgcttat gttagaaata tccactgatt tacaagtaaa tcaaccagtt
    12841 attactgtta caagtaatac gtttattagt atagaaaatt atctatcaat attagaatat
    12901 gaagttgatt taataagaat aaagactaaa gttaaaacaa ttaaaatatc tggggataaa
    12961 ctttcactta agtatattac tgatagtgag ataggtataa aagggattat ctacaatgtt
    13021 gagtatgttg attaggagga gatacacttg ataagtttta taaggggata ctatgttata
    13081 gttgtggaag gagtaggact cgaacaattt ttaaatcatc ttataagaaa tgggataagt
    13141 gtttacaatg taactagaat aaaaaatact aaaatggagt ttcatataga tagacaagat
    13201 ataaaagaat ttaagaatgt ttatagagga agtaagtttg atataaaggt aaagcaaaaa
    13261 actggggtcc cttttattat caaaagagtt tataagcaca aaggtatgtg gatttgtgct
    13321 cttgtttctt tatttttatt gatgtctaca tcacagtttg tgacagatgt atatatacaa
    13381 tctcctgaag gtataaaaaa agaagctctt agaaatgagc tttataaggt tggagtaaga
    13441 ccaggagtct ataagaagag tattgataga aaagaagtta gagaccatat gatgtcaaaa
    13501 tttaatgatg tggcatattt atctatcaat gtaaaaggaa caaatatatt tgttactgtt
    13561 acaaaaaagg cagaatccct aaaatctaca gaccaatcaa attattgtaa tgtaattgct
    13621 ttaaaaaatg gtataataga aaaggtaatc cctagaagtg gtaaatcagt tattaaatct
    13681 ggagacatag tccaaaaggg agatgtctta ttaaatggag ctaataccaa gtcaatacca
    13741 gaagtatggg caagtacttt ttatgagtcc acaaaaaagg caagttatgt agatactgta
    13801 aataaaaaaa ctggagaaaa gaaaaatata tatacactaa gtttttatga taaagagttt
    13861 acaatgagaa aaaatataaa atataaagat tatgttgttg aaaataaaga aaaaaaacta
    13921 tcaataggaa actatacttt tccaataaag ataaaaacga gtacttttta tgaaacaaaa
    13981 aaggttgaag taaaaaggaa taaagaagag ttaaaaaaag aattatctga aaaagcttta
    14041 aaagagttag aatacataat cccagcttcg gctagaataa tagatgtaaa acataacttt
    14101 aaggttaata aaaatatgtt agaatattta ataacagttc aaactagtga aaatattgct
    14161 aaaatttatc ctcttagtaa gtcagaagca gaaaggttta taaaggaaga aagtaaacca
    14221 gatgaaggtg aagaggaagt tccttccaat ccagaaaaaa gaccattaaa tgatataaga
    14281 aatgagtttg atgaggataa taaggataat aaagatcaaa acaattctga tgaaaataat
    14341 agtaatcaaa atagtaataa tagtcaaaat aataatagca ataacaacta ataaaattaa
    14401 acttaaaatc ttaggaggac taattcaatt gataatacaa aagaaattta caatagcaga
    14461 tggtaacttt gaaagagagt tatttggcaa ctttgatgaa aatgtaaaat taatagagaa
    14521 gactttaaat atagatgtaa tacttagaga aggcaatata attttaattg gagaagaaaa
    14581 aaatgtagat tctgcattaa aacttatgaa tgaattacac caaactgtat caaatggtaa
    14641 gcatttagat aagcagagta tttcttattc attatctctt ttgcttgaag gaagtgaaca
    14701 aaaaataaaa gaacttgagg ggacaatcgt cataactcaa aggggaaaag ctgttcaacc
    14761 taaaacttta ggtcaaaaag aatatataaa acttatagaa aataatgata taacttttgg
    14821 tgttggacct gctggaacag gaaagactta tcttgcggtt gctatggcag taaaagcttt
    14881 taaaagagat gaagttagta gaattatact tacaagacca gctgtggaag caggagagag
    14941 tctaggtttt ttaccaggag atttaaagga caaagttgac ccatatttaa gaccactata
    15001 tgatgcctta tttgaaatgt tgggtgctga taaatttaat aagtatttag aaagaggtac
    15061 tattgaggtt gcaccacttg catttatgag aggtagaaca cttgataatt catttataat
    15121 attggatgaa gctcaaaata ctacttctga acaaatgaaa atgtttttaa ctagacttgg
    15181 atttggctct aaagctgtag ttacaggaga tgtaactcaa acagatttac cacaaaataa
    15241 gaagagtggt ctaatacaag ctacagagat tcttaaaggt gttccaggta ttgggtctat
    15301 aatgctaaca gatagagatg ttgtaagaca tgagttggta caaagaataa taagagctta
    15361 tgagaagcac gacaaaagag aagaatttaa aaaagaagaa cgtaaaaaag cgaaaatgca
    15421 ggaaaagact ttcaaaagaa agtaaaagtg tagtaatata gatatatagc attattaatg
    15481 aataaaaagt aggtgtagtg aatggatttg atactagatg atagacaaga taaattagaa
    15541 gtaagtgagg agttaattga aaagataaag gatataatca tagaatgttt agattatgaa
    15601 ggatatgatg ataattatga agtgagtctt tcttttgtag ataataaaga gattcatgaa
    15661 ttaaatagag aatatagagg agttgataga gtgactgatg ttttatcatt tcctctttta
    15721 agtgatgatt ttgaggatgt tgagttagaa gaagaatccc taggtgacat agtagtatct
    15781 cttgaaagag ccttagaaca gagtatagag tataaccata gctttgaaag agaagtatgt
    15841 tttttaatat gtcatagtat gtttcatctt ttaggttatg accacgatac agatgaaaat
    15901 acaaaagaaa tgagagaaaa agaagaacac atattaaata agttaaacat aacaagggag
    15961 tagtttttat gaaaccagaa aaaactcgtc aaggtataat taaagcattt aatgcagcta
    16021 tagaagggat attgtataca tttaaatttg aaagaaatat gaaaatacat tatttaggtt
    16081 cagttgctgt tcttataata agtttgtttt ttaacttttc aaaattagaa atgataatgt
    16141 tacttatgtc catatgctta gttgtagttg ctgaaatgtt taatacagct atagaaaaag
    16201 ctgttgattt agtaactgat gaatatcatg ttcttgctaa gatagcaaaa gatgttgcag
    16261 ctggaggcgt tctagtggca gcactaaatt cagtagtagt tggatatatt ttgttttatg
    16321 ataaattgac agatatatct ggaatattaa tttataaaat aagagaatca gaattacata
    16381 taaccttgat atgtatatta ttggttctta tagctgttgt agttgtaaaa gcattgactt
    16441 ctacaggtac tcctctaaaa ggaggaatgc caagtggtca tgctgcctta gcatttgcta
    16501 tagcaactgc aattacactt atgactgaaa gagttgttgc ctctactctt gcatatataa
    16561 tggctgtatt agttgcccaa agtagaattg aaggaaaaat acataccttt tgggagacta
    16621 ttgctggagc tttgttaggt gtgttgatag ctatattagt atttcagctt ggaatgttct
    16681 ataattaaaa taaatgtaca taaaatattt aaaataaaac aaatctgtgc taattaaatt
    16741 tttatgatat aatgtagagt attaaataaa aataactttt aattattgta tacaggagga
    16801 gttgttgtgg ataacataga attgttaagg ttggcagaag atgccagaca acattcttat
    16861 gctccttact caggttttag agtaggtgca gctcttttaa ctaagagtgg taaagtttat
    16921 actggatgta atatagaatg tgcatcatta ggtggaacaa attgtgcaga aagaacagct
    16981 atttttaaag caatatcaga gggtgataag gatatctata aaatagctat agcaagtgat
    17041 aactcagaaa ataatgagca aacatatcca tgtggaatat gcaggcaggt aattatagag
    17101 tttggttctg atataaaaat aataacggga tatactaaag gagaggtgtt tgagcatagt
    17161 ataaaggatt tgttgccaaa ctatttctct ggaaatgatt taaaataaat ttaaaagtat
    17221 aaataaattt aagtaattaa aacaagaaga taaaaagtta ggagacagtt aatgttcaaa
    17281 tcaggttttg tcagtatagt gggtagacca aatgtaggaa aatctacttt aatgaataat
    17341 gtagttggag aaaaaatagc tataatgagt gataagcctc aaactacaag aaatacaata
    17401 caagcagtat atacagatga agaaatgcag atagtattct tagatacacc aggtattcac
    17461 aaaccaaaaa ataaattagg tgaatttatg gtaaaggcag caacagaagc ttttaaaaat
    17521 gtagatttaa tattatttgt agttgatgat tctaaaaaaa taggtcctgg agatagaaag
    17581 ataatagagg atttaagaag tgttaagaca ccaataattt tagttgtaaa caaaatagac
    17641 caactagacc aaaaagatga gctatttgat ataatcaaaa tgtatgatag agaaggcatt
    17701 tttaaagaaa tagtaccaat atcagcatta aaaggaaaga atacggatac cttaataaaa
    17761 gttatacaaa attatttaga agaagggcca aagtattttc cagattatat gattacagac
    17821 cagccagaaa gagtattaat agcagaactt ataagagaaa aagttcttca ctatcttaat
    17881 gatgaaatac ctcatggtgt agctgttgaa attgaaaaaa tgaaagcgag aaatgataag
    17941 gaaatagtag atgtatctgc tgtaatatac tgtgaaagag attcacataa gggaataata
    18001 ataggaaaaa atggtaggaa actaaaagga ataggtaagt cagcaagaca agatatagaa
    18061 ttgcttttag gttcacaaat aaatcttcaa ttatgggtta aagtcaaaga aaattggaga
    18121 aatttacaaa attatataaa taattttgga tataatgata aataaaggtg ggttatatgg
    18181 ataggaaact ggatgcttcc caagatttat tatatgaagt aaaatcatta attgataata
    18241 ataaagtatt ggagttaaga gaattaatag aggaatatca tataattgat atattcgata
    18301 taatggaaaa tttagaggaa gacatgaaaa ttcaattatt tgaagtactt cctttagata
    18361 tggcatcttc tatattagaa gaaggtagtg tagagttttt tattagtatt ttatctaaac
    18421 tggatgtaga acactcgaaa aatatacttg aacttatgtc tcttggagat atggcagaca
    18481 agttgagtga acttgaagaa gaagaaagag aacacataat aaatcttttg aatcaagaga
    18541 atgccgatta tgtaaaagag ttactattct atgatgaaga ttctgctggt ggaacaatga
    18601 ccactggata tatttctata aataaagata tgacagctct tgaggctata gaccatatga
    18661 gagaagaagc tgaagaagct gaaactattt attatatata tgtggttgat gatgaagaaa
    18721 aactagttgg agtattgtca ttaagagaat taataatagc tagagacgca aatatagtag
    18781 aagatttgat gagtgaaaat ataatctctg tttatgtaga tgaagataga gaagaagcag
    18841 taagattagt atctaaatac aatttaatag caattccagt agtagacaga caagaaaaat
    18901 taaaaggaat aataacagta gatgatataa ttgatgtaat ggaagaagaa gcaactgaag
    18961 atatgtataa atttgcagga agttcagaac atgaaagaga agttgctgaa aaagaaaacc
    19021 ctacattgag agagcaaata atatcagcac ttagaggacg attaccttgg ttaattatta
    19081 ccttagttgg agggttgttg gcttcgttaa tactttctaa cttagactat ataatgaatc
    19141 ctgtatatgc tccattagta ttttttatac ctgtagtaat tggtatgggt ggaaatattg
    19201 gaactcaatc atcatctgtt acagtaataa cattatctaa taaggattta aattttagca
    19261 atgtggttag agaaggtatt gtaggtatta ttacaggtct tttgtgtagt ataataacag
    19321 gtattgtaat ttactttgtt atgagaaagt tagacattgt attaattgtt tcaatatcat
    19381 tatttataaa tatggtttta ggtgcaacaa taggtgcgtt tatgcctgtt ttattaaaaa
    19441 aaatggatgc agacccatct acagtttcat caccaattat atctacagct cttgatataa
    19501 ctggtatagc agtttacttt ataataacaa cggcattatt gtcaaaaatt gtttaataac
    19561 tttatgtatg atttatcctc ttcttactaa aaatataagt ataaatgtaa gaagggggtt
    19621 ttttaaaaat gaacaatatc agttgggaag tttttaaaaa aacaggtagt atagatgcat
    19681 atttatattt ctgtgattgc aaaaacatac atgaagaaat tgaagaagta agggagaaaa
    19741 aagaagacga tgataatcct gaacacccag gggatagtac ttaaagctat aaggtataag
    19801 gaaagtgata taatacttac actatttaca agaaagcttg gaaaagtatc tgcaatagca
    19861 aaaggagcta aaaaaaataa gagctctttg ctttcatcat cacagttatt ttcttatagc
    19921 aattttacct taaaaaaaca aggtaatatg tacaaggtta ctcaaagtga aataataaaa
    19981 agtttttata atatatccta tgatatagag gcattttctt atgctacata tattacaaaa
    20041 ttagttgaaa attctatact tgaaaatcag actaataata ggctatttat attacttgcg
    20101 cagactctgt atttgtatac acaggataat acagacaata ggtttataac agcagcattc
    20161 gagttaaaat ttttagacta tataggattt aaacctatag taaataaatg cattaattgt
    20221 gaatgtaaaa ttttacaaaa ttctgtgttt aatatctacg aaggtggtat actatgtagt
    20281 aagtgtagta aactttttga taataatata aaattagact taacaactat aagtcttatg
    20341 gaatatgtat taagaaatga tattttaaca tgtagtaaag ctaaagtatc aaaatatata
    20401 acacatgaac ttgagaatat tctagacaag tatttgaaag tttatgttga taatattaat
    20461 tttaaatcat tacacgtatt gcaaagtgta aaaaataata agggagtgga taatgatgag
    20521 tagtaatata actattgaaa tggttgattc agtctttgaa agagttccag gagcaactta
    20581 tgcagaagca aaagaagcat tagtaatgtg caatggagat gtaattgagg cagtaatata
    20641 tttagaaaat aaaaaaaata cttgtaattg taaagcaaaa tctgctaaag aaactatgga
    20701 agaagtattt ggcaaagatg gagaaaatat aaagtttcaa ttaaaagagc ttcttagaaa
    20761 aagtagtgta gtgagaataa tagttgaaaa agatggaaaa actatgatga atattccttt
    20821 aacagttgga gttgttggat tagcttttgt accattagct actttagttg gattatcagc
    20881 tgctgttata agtaaatatc gtataaaagt tcaaaatgaa gaagatggag aaattgtaga
    20941 tttaggtgaa ttgaatgaag aaaaacttca cgttttgaag aatatgataa ctaatgcagc
    21001 aaaagatgtg aaggatgtag tagttgacaa aaaagaagat gacaaagatg taactgctga
    21061 ccttatgaaa gaagaatctg aaaagaataa agaagacgaa gacgaaaata aatagatata
    21121 aagtgacttt taaaaaatga agagaagata attataagaa ttatcactaa cattgacaaa
    21181 ttttatagaa tttgatattc taaaagttgt agaagaacta ttaaaatagc ctttcgtgta
    21241 gacgagaggc tttattgtta taggagggat ttttatgaat tttcaagaga tgatactggc
    21301 gttgcaaaaa tactggtcaa agcaaggttg tatcatgatg caaccttatg atattgaaaa
    21361 aggtgcggga actatgaatc ctaatacttt tttaagatca ttaggacctg agccttggca
    21421 agtatgctat gtagagcctt caagaagacc agcagatgga agatatggtg aaaacccaaa
    21481 cagactatat caacatcatc aattccaagt tatactaaaa ccttctccag ataatataca
    21541 agaattatat ttggaaagtt tgaaagagat tggaattgac ccaagtgagc atgacataag
    21601 atttgttgaa gataactggg aagctgctac agttggtgct tggggacttg gatgggaagt
    21661 ttggctagat ggtatggaaa taactcaatt tacgtatttt caacaagtag gtaatattga
    21721 atgtgagctt gagacaggag aaattacata tggattagaa agattagcta tgtacattca
    21781 agaagttgat agtgtttatg atttaaaatg gaatgataaa ataacttatg gtgaagtatt
    21841 taataaagct gagtatgaaa actcaatgta cgcatttgaa ttatgtgatg cagatatgtt
    21901 gtttaatctg tttgatatat atgaaaaaga agcattaaga cttatggaaa atggccttgt
    21961 aataccgtca tatgactatg tgttaaaatg ctctcatgca tttaatacat tggatgcaag
    22021 aggtgcaata ggagttagtc aaagagcttc atttataggt agagttagaa atatggcaaa
    22081 gactgttgca gaaacttttg taaaacaaag agaagaaatg ggattccctc ttttaaagga
    22141 cggtgacaaa taatgaaaaa ttatctttta tttgaaatcg gtgttgaaga aatgccatca
    22201 agatttgtag gcagtacact agaacaatta aaaaacaatc ttagtaaatt atttgatgaa
    22261 aatagaatag cttttgataa aataaatgct tatgggacac caagaagact tactttagta
    22321 gtcgaaggat tgagtgatag acaaagtgat ttagaagagg aaataaaggg tcctgctaaa
    22381 aaaattgctg ttgatgcaga aaataattta acaaaaccag cattaggatt tataaaaagc
    22441 aaaggattaa gcgaatctga catatatttt aaacaagttg gaaaagaaga atatatattt
    22501 gcgactataa agcaagatgg aaaagaaact tcagaagtac taaaagacat attaccagag
    22561 actataaaat ctgtagtatt cccaaaagct atgcgttggg gaggaaaaaa tcttaaattt
    22621 gcaagaccta taagatggat agttgcattg ttaaatgata aagtattaga gtttgattta
    22681 gaaggaataa tatcttctaa tgtaacaaaa ggtcatagat ttttaggtga aagtacaata
    22741 gaagttgatt ctatagaaga ttattttgaa aaattagaaa aaaattatat agttttagac
    22801 caaaacaaga gaaaagaaat gataagaaaa caatgtatag aagtagcaaa ttctttaggt
    22861 ggagaagttg aatttgatga agatttactt gaagaggtaa cttatttagt tgaatatcca
    22921 actgcttttt atggagaatt tgatgtggat tatataaaac taccaaaaga agttgttata
    22981 actcctatga aacaacatca aagatatttt ccagtactta aagaaggaaa actgttacct
    23041 aactttatag ctgttagaaa tggtgattct tacagaatag acaatgttaa agctggaaat
    23101 gaaaaagttt tagaagcaag acttgcagat gctttatttt tctatagaga agatactaag
    23161 agaaacttag aaagctacat agaaaaatta aaaactgttg tattccaagt aaaattagga
    23221 actatttacg acaaaacttt aagacttgaa aaattaagtg ctgatatact tgatagttta
    23281 ggtttagtag atgaaaaggc agatactata agggctgcta aattatctaa ggcagattta
    23341 gttactggaa tggtaggaga atttgatgaa ttacaaggtt ttatgggaaa agaatacgca
    23401 aaagttggag gagaaaatga tgttgtaagt gaagctattt ttgaacatta tcttccaaga
    23461 tttgcaggag atatacttcc taagactaat gcaggggttg ccttatcaat agctgataag
    23521 ttggattcaa tagcaggttt ctttgctata ggaatacaac caacaggttc tcaagaccca
    23581 tatgctttaa gaagacaagc tttaggtata cttagtatac ttatggacag aaaagttgct
    23641 gtggatataa aaatacttat tgaacatgct ttagacaatt attctgaatt agattttaat
    23701 aaagaagaag ttgttgagca aataatgaat ttcttcaatg agagagtaaa aaatctattt
    23761 aaagatttag gaataagata tgatgttgtt gatgctgttt taagttctga tataaatgat
    23821 gtttctgata tgcatatgag agctttagag cttaataatt ggctagaaaa agatgaatta
    23881 gtggagatgc ttactgcatt taatagagtt tctactctag ctcaaaaagc agaaagtgat
    23941 aaaattgatg aatctttatt aaaagaagat gctgaaatta aactttacaa tgaatttaaa
    24001 caagtaaagg taaaagttaa tgaattatta aaggataaga aatatggtat tgctttagat
    24061 gaatttgcat ctttaagacc agtagttgat aatttatttg atacagttat ggtcatggat
    24121 aatgatgaag ctattaagaa caatagactt gctttactta aacaagtata tgatactatg
    24181 ctaggaattt gtgatttatc taaaattgtt tataaataaa atttaaacta tttataagaa
    24241 ataaggctgt ctcaaaatag agatagtctt att
//
LOCUS       DAJMZY010000059        23930 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.059, whole genome shotgun sequence.
ACCESSION   DAJMZY010000059 DAJMZY010000000
VERSION     DAJMZY010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 23930)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23930)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23930
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.059"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            complement(<1..256)
                     /locus_tag="OE968_002244"
     CDS             complement(<1..256)
                     /locus_tag="OE968_002244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HCP7219521.1"
                     /translation="MIKETHERGGYIFALLILPFINNLYLVKYDIAYKIVLIIIYIYF
                     AYLGSLFPDIDMRGSYISKKFMLIYKLFGSRFRHRGFTHSL"
     gene            complement(369..1043)
                     /locus_tag="OE968_002245"
     CDS             complement(369..1043)
                     /locus_tag="OE968_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HCP7219522.1"
                     /translation="MSLFIISQCITSFAFTPENNKFKVKPLPYAYDALEPYIDKETMK
                     LHHDKHYQAYVDKLNAALEKYPELYNYSLCELLQNLDSLPKDIATTVRNNAGGAYNHK
                     FFFDIMTPEKTIPSESLKEAIDRDFGSFEKFKQEFQKSALDVFGSGWAWLVATKDGKL
                     SIMTTPNQDSPVSKNLTPIIGLDVWEHAYYLKYQNRRNEYIDNWFNVVNWNGALENYK
                     NLKSQD"
     gene            1246..3120
                     /gene="asnB"
                     /locus_tag="OE968_002246"
     CDS             1246..3120
                     /gene="asnB"
                     /locus_tag="OE968_002246"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HCP7219523.1"
                     /translation="MDGNISIYYKGDISKKEDIKFKIKESVNNTRLSSRIEYKDEEKT
                     FDFERFNVIDAIYGNKPFEKDGKVIVFNGNIYNYHEIKEELIKKGHNFTTNDDIEVLL
                     ASYIEFGKNCVHKIKGMFNFIIYDRENESIFGARDLFGIKPLYYINKENAIIFSSEYK
                     FLLEYMKNLNINERSLQSYFSFQYVLPEDTMIQGIRLIPAGHYFRVENGILSLKRYNK
                     LEFRSSTKFFYTKNHLGNRDVNEDDIRNIVVDSIVTHMEEEKEIGTFLSGGIDSSIIT
                     TVASQINPNIKSFSAGFSVKGYSELEVAKKTADKLGIENIQINITQDEYIKSLPNVIY
                     SLDDPIADPSEVGLYFLIKEAGKHVKVALSGEGADELFGGYNIYKEYSTMKSVVNSPT
                     YIKSILGRVSELMPNIKGRNYLYRATTPLEKRYIGNAKVFENSEVKRFFFKYKEKNIY
                     EYLLSNLYRDAQKNNYDYISKMQHIDVNTWLQGDILQKISKLSTAEQVELRVPFLYKD
                     VFDVAKNLRMEQKINKNNTKVLLREAFREIVPEHVVQRKKLGFPTPIRVWLKDSLGDI
                     VKETIYNSNVDEFIDKKYAIKLLDTHLKGHRDNSRKIWTIFTFCLWHQLFIEHKNVEY
                     "
     gene            complement(3212..4648)
                     /locus_tag="OE968_002247"
     CDS             complement(3212..4648)
                     /locus_tag="OE968_002247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HCP7219524.1"
                     /translation="MICTIKPLKISIKKSTEPLIEFISDTTYKNKRSSYIKEVYFTRY
                     IGVDDSIDKYIEKIKNIDTYFFNNPTIPYIRLNNLKINFDKEQTDKMLKIFNIYNSSK
                     FNSWDLYNIDFPCKIENDTLNWTKKIAFKNTLDLFSTSMPNCTSSIIKNFAVKLLCWI
                     DYFLPKLFYNKVKTTISPKIVYFGNIKRQELFFLYFLSQLGCDILYINPNKDILDLYP
                     ECSKFSTLFELSRKTPNILEIPFERHITNINYSENTNKTSPTTNKPNSKNTLNNTNLT
                     SKKIVQDEEVELSYEDLAKLSASVVMIVVCNNENKPFKSGSGVVINNEGYILTNLHVV
                     NDGYSFLVRFENDDKVYTSYQIIKYHSDYDLAVIKVDRKCKPIPVKVSKKPVRGQKIV
                     AIGSPLGLFNTVSDGIISAFRDFETVQMIQFTAPISSGSSGGALLDMFGNLLGLISAG
                     YDDGQNLNLAVESNLVKIFANNFIEIVN"
     gene            4977..5555
                     /locus_tag="OE968_002248"
     CDS             4977..5555
                     /locus_tag="OE968_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_126936537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HCP7219525.1"
                     /translation="MGITLSKGQKVDLTKGNPGLKNILVGLGWDTNKYDGGFDFDLDT
                     AAFLTGASGSVTNDGDFVFYNNLKHTSGAVEHLGDNRTGEGDGDDEQIVVDLSKIPGE
                     ISKISFTVTIHDATERRQNFGQVSNSYIRIVDKDTNEELIKYELGEDFSIETAIVVAE
                     IYKHNGEWKFNALGSGFEGGLAALCGNFGINL"
     gene            5594..6172
                     /locus_tag="OE968_002249"
     CDS             5594..6172
                     /locus_tag="OE968_002249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_126936537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HCP7219526.1"
                     /translation="MAIVLKKGQKIDLTKGNPGLKNIKLGLGWDTNSFDSGYDYDLDV
                     SVFMVGESQRVEKDEDFIFYNNLKHPSGAVEHLGDNRTGEGDGDDEEILVNLETMPKH
                     IQKIAVTVTIYEAAERRQNFGQVSNSYIRVLNSENDEEILRYDLGEEFSIETAITVCE
                     IYKYNGEWKFSAVGAGFEGGLEALCRNYGLNV"
     gene            6258..6887
                     /locus_tag="OE968_002250"
     CDS             6258..6887
                     /locus_tag="OE968_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HCP7219527.1"
                     /translation="MSINLSKGDKIDLKKSNPGLSNILVGLGWDPVQQSGGGFFKSLF
                     GGGQADIDCDASVFMLNQEGKLSGIKDLIYFGNLKSACKSVLHTGDNLTGEGTGDDEQ
                     ILVNLDKVPSNIHKLLFVVNIYNCVDRKQHFGMIENAYIRVEDQGNKKEIAKYNLSDN
                     YSEKTTLIVGAIYRKDGSWQFKAIGEGTKDAGLKEVMQNLDRIECAYGI"
     gene            6877..9636
                     /locus_tag="OE968_002251"
     CDS             6877..9636
                     /locus_tag="OE968_002251"
                     /EC_number="7.2.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium-translocating P-type ATPase, PMCA-type"
                     /protein_id="HCP7219528.1"
                     /translation="MEFNNDIKYYNVDKEEVTKDLSVNPEKGLSESEVKTRREKYGLN
                     EFTPKEEGSFWDDLKESLSEPMIVILIIAAVVSAVIGETHDAIGIVGAIAIGIAIGMI
                     TEGRSKKAAEALSKLTENIEVKVLRDGEVHQISKSELVPGDIVYIETGDMVPADGRLI
                     ESINLKIREDMLTGESDDVSKKCDVVVSMEEIESKGAVVVQEPIPAKQINMVFGGTLV
                     AYGRGALVVTSIGDNSEMGKIAQNLSETDEQTPLQIKLGNLGGLIAKVSSAVAGLLFI
                     FMVFQMISKNVLNVDMSGILPFLESIDPVKTAFTVCVALIVAAVPEGLPTMINMTLAI
                     TMQKMAKINALVTKKEACETIGSVSVICSDKTGTLTENRMTVEVAYVDGRYIESSEEE
                     INSYFEENCMINSTADVEHNDGDIKYLGSATECALLLYYKNVDYRQVRKNSNIVAQNP
                     FTSDSKRMTSVIGQDNHHVLLSKGAPEVLLELCSHIQRGKDIVPLTENIKHEILEEIK
                     KLQIKSMRTLGFAYKEISQAEEEAAVTAESDAMNVSAMENNLVFSGFVGIRDPLRKDV
                     IESVNTANKAGVSVKMLTGDNINTARAIGEELGLLKNNMRVVEASYIDTLDDEELKQE
                     IQSISIVARSKPDSKMRIVSALQKSGDVVAVTGDGINDAPALSKADVGIAMGISGTEV
                     SKNAADIILTDDSFSTIVKGIKWGRGIYDNFQRFVQFQLTVNVIAFLVAIISQVMGQE
                     MPFTTIQLLWVNIIMDGPPALALGLEPVRDHVLNRKPVDRKANIISKSMVYTIVLNAF
                     YITAILMLQSTFNFLGVDEAHKGTVMFALFAFSALFNAFNCREFNADSIFPNFTHNKL
                     ALQIIVLTGIAQVIFTQLFQDFFNSVAMDFMTWVKVLCVAASVIVVNEVVKCIIRLVK
                     PKKTA"
     gene            9723..11285
                     /locus_tag="OE968_002252"
     CDS             9723..11285
                     /locus_tag="OE968_002252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YceG family protein"
                     /protein_id="HCP7219529.1"
                     /translation="MGDSKVFEKIFSSQSDRGNYTPSKGYLSYFISYIGLEDEVLYNL
                     EIFKTKQNIDSKKDIALFTDVIANPSDFDIINYFKSGLQKYRTSMEDVDINILGFEEI
                     DYKIKQAMDRVLKEEEKEFTNDRVKQNFIVKIMAWIKIYIGALDINKNEAPKVIFYGD
                     IKKHEVYLLLILYLAGFDVLYLNPNSKSNIDILKSERYNIEFEEANIIEEKISFEERV
                     ILGEKIDKSSVKKAFTVGAEASKRISEELLNDAGFIKPWQLQDRKIKNLLLSSTVDEI
                     SIYWNQPLKLRPGFKFNDAIVEAPNFLSKINGIYNDKNEYIKFLDLLRDSESSTFIEF
                     NGDVDRFSKAFTREAFSLSFLLDSKGAIDKNSVLNNKDYSISTLALNQQIMILEKVEE
                     LLEGSMFLNGLSGEDKIKGLFTVLHMDKKFVHMMNNFDYSLINPKLIIYMYKSIVFDK
                     EIVFLMLLLSKIGFDIIILCPGGENNIENVINNQLIDVHRLDKMVYDLKLNSLENDIP
                     LLKKIFGKRRRF"
     gene            11286..12422
                     /locus_tag="OE968_002253"
     CDS             11286..12422
                     /locus_tag="OE968_002253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HCP7219530.1"
                     /translation="MGININSFSKDKNSVEVTENLPTAVQEENFDIMEYTNNKKNELR
                     KSKEVEALTSLIEVENPDTILQFGRKASEGVARVSDSLLNTIKLNRNEENSKMLVHLT
                     KIMDKFDLDDFQETKEPNFVQKLFKKANNAIEMMFQKYETLGGEVEKIQIELEQYERD
                     IALSNKQIGAMLNENFEFYNELQKYIVAGEMAIEEMDNEILPFFKQKSETSGDQMDVV
                     NYQELLKVYDMLNQRVYDLRIAENIAIQTIPMLRGMQHNNYGLIRKINSAFVVTLPVF
                     KQCLSQAILLKKQELQAKSLKALDDKTNELLLRNAQNVSTQSAQIARMAGTSSVQIET
                     LEKMYNTIKSGIDETMRIEENNRALIKDNTKRLEELNTTIIYNK"
     gene            12486..13562
                     /locus_tag="OE968_002254"
     CDS             12486..13562
                     /locus_tag="OE968_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HpcH/HpaI aldolase/citrate lyase family protein"
                     /protein_id="HCP7219531.1"
                     /translation="MKYFDYICKDDLERIFLKEPEDFSAKTEKDVLKYALGAFLYVPA
                     TQYNMIYKSIIGDVKGVRPLAICLEDAVGVNGELEAIENLRLILKNISNESITNKDGI
                     PLIFVRIKDVEQLLRIKEIIIKNRHSITGILIPKANSELIENCIEALDSMNLQDMYVI
                     PIIETKEFIYNEKKELSFTNLYNAILRHKSRILSIRVGITDILGMYGIRRDKNFSIYN
                     NLICSSFILDIITYLQRPELDIPISGGVSEFFDMTNKDIRNKYIEEILLDKYHGLIGK
                     TVIHPMQIQIVQALSTVSYEDFTDALDILDSTDSKYGVSKGVLGERMNETNPHFLWAK
                     KTLILSKIYGVLNKGVDYEELLKF"
     gene            13540..14778
                     /locus_tag="OE968_002255"
     CDS             13540..14778
                     /locus_tag="OE968_002255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosyltransferase family protein"
                     /protein_id="HCP7219532.1"
                     /translation="MKNCLNFNCEIDIIDNPLNLELNDFLDVGIRNNSKRRFLFISKK
                     LGKHLACKPSEMDNLGKLMATIYNEKNKEESNGTVIAFAETGTAVGHSFFDYLCGDYE
                     FIHTTREQFDELENLEFLEEHSHATDQNLYFGMLNNFKFGDEIILVDDEITTANTCMN
                     IIRKIQSIYPKKKYTICSILNWVSDENLSKVTRLERELDCKIDFVYLFKGNFKFYIDE
                     DIISNYNDNYSITKLETISSDKVNLVVNHIYVDLEDYIGNKKYVKYTGRFGINRREQF
                     RLKEIVKRESKKITMASKESLKNEKEKILFLGTEEFMYIPMLFAKEKENQYDIYYHST
                     TRSPIINIDKNNYPIKSKFMLKSFYNIDIQNYIYNIDKHNFSKCYLFVELNKSENSYL
                     EFIDIIKKTSIKELTIVCCS"
     gene            14832..15920
                     /locus_tag="OE968_002256"
     CDS             14832..15920
                     /locus_tag="OE968_002256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine protease StiP family protein"
                     /protein_id="HCP7219533.1"
                     /translation="MRDFSTYSKDDVIFLLKDISNLIEEEGNKERELKIQNGRHYSEM
                     IPIEYEVSEDYLNLYHEKLRENKDKLAFSIGVMCEKIIKKNGNDVVLVSLARAGTPIG
                     ILAKRYIRSKYNVSLPHYTISIIRDKGIDMNAIEYIVKNHPSSKIQFLDGWTGKGTIS
                     KELEKACDELNVKFKKYFDSTLAVLADPAGYSGLYGIREDFLIPSACLNSTVSGLVSR
                     TVLREDLISKNDFHGAKFYRHLKDKDESMNYIETIEECFKNQFKNISDEVENWESDII
                     TRDGYFDVLNIKEKYNITDINFIKPGVGETTRVLLRRVPYKILVKDLNDKSLDHIFIL
                     AKEKNVEVEQMDLKAYKCCGIIKNMKDI"
     gene            15948..16739
                     /locus_tag="OE968_002257"
     CDS             15948..16739
                     /locus_tag="OE968_002257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HCP7219534.1"
                     /translation="MIVFSDLDRSIIYSNKFLNADSKYANIEIYREKEISYISLDTIN
                     LIKQIQYYGMFIPTTTRTVEQFKRIEFNKYGIYFPWSITSNGGVILKDNEILKSWSEK
                     IDKLKSDYEPIESMIHKFKDYLNVDGITNFKVAEDTFFYIVVDLSRFNLDSIKEYTNI
                     LESKNWKFYVSGRKIYFIPKEISKENAIKYLTKELGIEYFYAVGDSIMDYGMLNISNK
                     SYVLKHGDINKNEIENSFISSSFNGMSGTEEILSNILDENCLLNI"
     gene            complement(16854..17408)
                     /locus_tag="OE968_002258"
     CDS             complement(16854..17408)
                     /locus_tag="OE968_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HCP7219535.1"
                     /translation="MNIDVGSKIRSLRKSKNISISTLAKNSDLSTGLISQIERNMVVP
                     SIVAMWKISKALDINIGYFFEEIGREDSDIVVKKNNRKKIVTNDSTKFYELLVPNLSG
                     KKIEFILVTLDGHTHKNSEFVTHEGEECGYIIKGKMKITLGNKEYLLEEGDSFYFNST
                     IPHVYENYDDEVCISVWAMTPPSF"
     gene            17604..18806
                     /locus_tag="OE968_002259"
     CDS             17604..18806
                     /locus_tag="OE968_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF819 domain-containing protein"
                     /protein_id="HCP7219536.1"
                     /translation="MKSFVSPDNIWVLWAVVTGWAAFSIYLEQKYNWASKVSGAIIAL
                     VGAMLLSNLNIIPVESVVYDQVWGYVVPLAIALLLYQCNIKKIWKESGRLLIIFLVGS
                     VGTVLGAMIGFLALKNVVPDLNIVAAMMTGSYIGGNVNFAAMSGAFDAPGELVSATVV
                     ADNLLMALYFFVLIAIPSIGFFRKHFKHPHVDEMESIGITEGETVAANYWGRKEISLK
                     DIAIAIGSAFIIVAVSVELSTWFKAIIPLSNPFLAMLNTLFGNQYLIITTLTMLFATF
                     MPNFFGDIKGAQELGTFLIYIFFVVVGVPASITLIIQKSPLLLLYCGIMVLINMLVTF
                     IVAKIFKFSLEEAILASNANIGGPTTAAAMAISKGWSKLVGPILIVGTFGYIVGNYFG
                     LLVGNILI"
     gene            18863..19843
                     /locus_tag="OE968_002260"
     CDS             18863..19843
                     /locus_tag="OE968_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HCP7219537.1"
                     /translation="MIFDGHSDTWADVTIRRLNGEKDVFRRIHLDNFKRANIEGAIFV
                     IWIDPPYDKEPEKRVKQIISSIKDEIEDMKDVVNIVKKYSDIDKGISENKINILIGLE
                     GLSHIGRNIDLLDYFYKEVGARHASLTWNEQNELATGCLGDENRGLTEIGKKAVNKME
                     KLGMIVDVSHLNEKSFWDLMSVASKPVIASHSNARSLCDAKRNLTDNQLKEISNTGGL
                     VGINSFRGFTNSNPKKQDLIHLVDHIDYMVNLIGIEHVSFGFDFSDYLGKETIGSFTG
                     NASVPSVDGLESTHTAQNIVVELENRGYKKKDIELISSGNFYRLFKDILK"
     gene            20091..21044
                     /locus_tag="OE968_002261"
     CDS             20091..21044
                     /locus_tag="OE968_002261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HCP7219538.1"
                     /translation="MKKRYLVIGIIILSYFSLFIGAEDINIMHIFAKNQHKLMIFIMS
                     RIPRLISILIAGVGMSIAGLIMQQISKNKFVSPTTGATIDAAQFGIVICMLLVPTASI
                     FTKTIIAFVFSLVGTFTFMKIIGKLQFKNIIFVPLVGIMFGNIIGSMTDFIAYKYDLS
                     QNVSSWMQGDFSMILKGNYEILYITIPLIILAYIYANKFTVVGMGMDFATNLGLSYKR
                     IVNIGLIIVALVTVCVVVTAGNIPFIGLIVPNIVSLYMGDNIRASIWYTGLLGAIFVL
                     ICDIFGRIIIYPYEISIGLTVGVIGSILFLYLILRRNVNEA"
     gene            21034..21990
                     /locus_tag="OE968_002262"
     CDS             21034..21990
                     /locus_tag="OE968_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HCP7219539.1"
                     /translation="MKLSLNQKIYFVSILLFISIALFIIYGIDMNHLEYALSQRIPKI
                     FAMVLGGGCIAFTTVVFQTITNNQILTPSVLGLDSLYVMIQTIIVFIFGSSSSLIINE
                     NYNFIINVAMMIGASLLLYKTLFEKNKNNIFFLILVGMIFGTLFKSATTFIQVMIDPN
                     EFLALQTSIMASLNNINTNVLLIAFIIIIAIIPFIYDEIKYLDVLSLGKEQAINLGVD
                     FDKAVKKMIILIAILVSISTALIGPMTFLGLLLANITREIFKTYKHTYLISGSMLIGM
                     ITLIIGQFFIQHVFKFDTTLSVVINFIGGIYFIQLLLKGANR"
     gene            21987..22742
                     /locus_tag="OE968_002263"
     CDS             21987..22742
                     /locus_tag="OE968_002263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCP7219540.1"
                     /translation="MIEIKNIFKRYKNKNVVDDVSFSIEKGKITSFIGPNGAGKSTVL
                     SIVTRLIGGDGGEVIIEGKSLTNYSNKELAKKIAILKQSNNITLKLTIRELVGFGRFP
                     YSEGNLTKEDENYIDEAIEYMKLTDIQHKYLDELSGGQRQRAYIAMVIAQDTEYILLD
                     EPLNNLDMNHSVQMMKVLRSLCDELDKTIVLVMHDINFASCYSDNIVALKNGKVKKVG
                     RTDEIVNEKVLEDIYEMNFNIKNINGNRICIYF"
     gene            22834..23799
                     /locus_tag="OE968_002264"
     CDS             22834..23799
                     /locus_tag="OE968_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HCP7219541.1"
                     /translation="MNKKAAIVAAVAIIGLVTVFALGGSKKNESKTSENSNNTMKITH
                     NLGETDVKLNPKKVVVFDYSALDTMDALGVAENLVGLPKASLPASLEKYKDDKYADLG
                     GLKEPDLEGIKSANPDLIIINGRQEDFYEQLSKIAPTISTSKDDKKYLESVKNNIDKI
                     AKIFGVEEKANQEFSKIEKKIETLNKKVTDKNLNALTIMVNEGNLSVFGEESRFSILY
                     NSFGFENKDKNIKESSHGQNITFEYIAKQNPEVMFVIDRGIATGSDVKESSTAKSVLN
                     NDIIKSMDAYKNDNIIYLDSPTWYVNDGGLTSLNKMIDDASKAVN"
BASE COUNT         9434 a         2519 c         4094 g         7883 t
ORIGIN      
        1 ttagactgtg agtaaaccct ctatgtctaa acctacttcc aaataatttg tatattaaca
       61 taaatttttt acttatgtaa gaacctctca tatctatatc tggaaataaa gaacctaaat
      121 atgcaaaata aatataaatt ataattaata ctattttata tgcaatatcg tatttaacta
      181 ggtacagatt gtttataaag gggagtatca aaagtgcgaa tatataacct cccctttcat
      241 gtgtttcttt tatcatataa aaatcctcct gaatcgtcac tataaacatt atattggtaa
      301 atttagacta tcttttatta tattatatag caaacataag tttttttcaa aaggatttta
      361 atatttaatt aatcttgaga ttttaaattt ttgtaatttt ctaaagcacc attccaattt
      421 actacattaa accagttgtc aatgtattca tttcttctat tttgatattt taaatagtaa
      481 gcatgctccc aaacatcaag tcctattata ggagttaggt ttttacttac agggctatcc
      541 tgatttggag tagtcataat agataatttc ccatctttag tagctacaag ccaagcccaa
      601 ccagaaccaa agacatctaa agcagatttt tggaactctt gcttaaattt ttcaaaagaa
      661 ccaaagtctc tatcaatagc ttcttttaaa gattcagaag gtatggtttt ttctggcgtc
      721 attatatcaa aaaagaattt atgattataa gctccacctg cattatttct tacagttgta
      781 gcaatatctt taggtaaaga atctaaattt tgcaataatt cacataaaga ataattataa
      841 agctcaggat atttttcaag agcagcattt aatttatcaa cataagcttg ataatgctta
      901 tcatgatgca gtttcattgt ttctttatct atataaggtt caagtgcatc atatgcataa
      961 ggtaatggtt taaccttaaa tttgttattt tcaggtgtaa aagcaaatga agttatgcac
     1021 tgtgagatta taaataaaga cataataact ggtattaata tttttttctt cataaaaatc
     1081 acctcctaat atagtatttc tagaaataaa aaaaatatga aatattaaca gataatttat
     1141 aagaatttaa tagcaatttc attttaaatt gaataagttt taaagccaaa gacaaaacta
     1201 tgaaatatag aataagacta aaggacagaa aggaattttg attatatgga cggcaatatt
     1261 tcaatttatt ataaaggtga tatatctaaa aaagaagata ttaaatttaa aataaaagaa
     1321 tctgtaaata atacaagact ttctagtaga atagagtata aggatgagga aaaaactttt
     1381 gattttgaaa gatttaatgt aattgatgct atttatggaa ataaaccatt tgaaaaagat
     1441 ggaaaagtta ttgtttttaa tggaaatata tataactatc atgaaataaa agaagaatta
     1501 attaaaaaag gacacaattt tactacaaat gatgatattg aagtcttatt ggcatcttat
     1561 atagaatttg gtaagaattg tgtacataag attaaaggaa tgttcaactt tataatctat
     1621 gatagagaaa atgaaagtat atttggagca agagatttat ttgggataaa accactctat
     1681 tatataaata aggaaaatgc aataattttt tcctcagagt ataagttttt acttgaatat
     1741 atgaaaaatt taaatataaa tgaaagaagc ttacaaagtt atttttcatt tcaatatgta
     1801 cttcctgaag atactatgat acaaggaata aggctgatac cagcaggtca ctattttagg
     1861 gtagaaaatg gtatactatc tttaaagaga tataataaac ttgagtttag aagtagtaca
     1921 aaattttttt atactaaaaa tcacttaggc aatagagatg tgaacgagga tgatataaga
     1981 aatatagtag tagattcaat agtaactcat atggaagagg agaaagaaat tggaacattt
     2041 ctgtctggtg gaatagattc atctattata actactgtgg cttcacaaat taatccaaat
     2101 ataaaatctt tttctgcagg ctttagtgtc aaaggatata gtgaattaga agtagcaaag
     2161 aaaacagctg ataagttagg tatagaaaat atccagatta atataacaca agatgaatat
     2221 ataaaatcat taccgaatgt aatttattct ttggatgacc ctatagcaga cccttcagaa
     2281 gtaggtcttt atttcttaat taaagaggca ggtaaacatg ttaaagtagc attgtctgga
     2341 gaaggagcag atgaattatt tggaggatat aatatatata aagagtatag tactatgaaa
     2401 tcagttgtca attcacctac ttatattaaa agtatattag gaagagtttc agaacttatg
     2461 ccaaacataa aaggaagaaa ttatctttat agagctacaa caccattaga aaaaagatat
     2521 ataggaaatg caaaagtttt tgaaaacagc gaagtaaaaa gattcttttt taagtataag
     2581 gaaaagaata tatatgaata cctgttgtct aatttgtata gagatgcaca aaaaaataat
     2641 tacgattata taagtaaaat gcaacatata gatgtgaata catggcttca aggcgatata
     2701 cttcaaaaaa ttagcaaact ttctacagct gagcaggttg aacttagagt accattttta
     2761 tataaagatg tatttgatgt agcaaaaaat ttaagaatgg agcaaaaaat aaataagaat
     2821 aatacaaaag ttttacttag agaggcgttt agagaaatag tcccagaaca tgttgttcaa
     2881 aggaaaaaat taggatttcc aactccaata agagtttggt taaaagattc tctaggggat
     2941 attgtaaagg aaactattta taattcaaat gtagatgaat ttatagataa aaaatatgca
     3001 ataaaacttt tagatacgca tcttaaaggt catagagata attcgagaaa aatatggact
     3061 atatttacat tttgtctatg gcatcaatta tttattgagc ataaaaatgt cgagtattaa
     3121 tacttttttc aatattaatc agagggcaaa agcatgcaat gttttcaccc tcctgattat
     3181 tatggaatag gataagtaga attttgattg attagtttac tatctcaata aaattattgg
     3241 caaatatttt gacaagatta ctttcaacag ctaaatttaa gttttgtcca tcatcatatc
     3301 cagcggaaat caatcctagt aagtttccaa acatatctaa aagagctcct cctgaactac
     3361 cactagagat tggagctgta aattgtatca tttgaaccgt ttcaaaatca cgaaaagctg
     3421 aaataattcc atctgaaact gtattaaaaa gacctagagg gcttccaatt gcaactattt
     3481 tttgacctct cacaggtttt ttactgactt taacaggtat tggcttgcat tttctatcaa
     3541 cctttatcac agctaaatca taatctgaat ggtattttat aatttggtaa gatgtataaa
     3601 ctttatcatc attttcaaat ctaactaaaa atgaataccc atcattgact acatgaagat
     3661 tcgtaagtat ataaccttca ttatttatta ctactccaga accgctctta aacggtttat
     3721 tttcgttatt gcacacaaca atcataacaa cagaagctga taactttgca aggtcttcat
     3781 aagaaagttc tacttcctca tcttgtacaa tttttttaga tgttagattt gtgttattaa
     3841 gtgtattttt agagttaggt ttattcgtag taggagaagt cttattggta ttttcactgt
     3901 aatttatatt tgtaatatgc ctttcaaaag gtatttctaa tatatttgga gtcttcctag
     3961 aaagttcaaa tagagtagaa aattttgaac attcaggata taaatcaaga atatctttat
     4021 ttggatttat atataaaata tcacacccaa gttgtgataa aaaatataag aaaaaaagtt
     4081 cttgcctttt aatatttcca aagtatacta tctttggtga aatagtagtc ttcaccttgt
     4141 tataaaataa tttaggtaga aaatagtcta tccaacacaa aagtttaact gcaaagtttt
     4201 tgatgataga ggatgtacaa tttggcatac ttgtggaaaa taaatctaaa gtatttttaa
     4261 atgcaatctt tttagtccaa tttaaggtgt cattttctat tttacatgga aagtcgatat
     4321 tatataaatc ccaactgtta aacttagaac tattataaat attaaaaatt ttaagcatct
     4381 tatctgtttg ttctttgtca aaatttattt ttagattgtt taatctaata tagggaattg
     4441 taggattatt aaaaaaataa gtatctatat ttttaatttt ttctatgtat ttatcaattg
     4501 aatcatcaac acctatatat cttgtaaagt agacttcttt aatatatgaa gaacgcttat
     4561 ttttataggt agtatcagat ataaattcaa ttagaggttc agtagacttt tttattgaaa
     4621 tctttaatgg tttaatagta caaatcatat tttttctcct ataataagat gatataatct
     4681 attataaaac aacttaaaac aatatagtac aataattttg tagtttcaaa ataaaatatg
     4741 tacttgttta tataaatgat atataattac atattaaaca tagcttttat gcatttaata
     4801 aagtatgtaa aatctatgta aaaagtaaga aatataaaca tttttttaat tatattttaa
     4861 aaatatcaag caagttttat tcacaaatga ataaaaaatg ttataatatg attaaagaaa
     4921 aagataaata attagcaaga tttgtttagc taaaattaac aagggagcga taaattatgg
     4981 gtataacatt atcaaaaggc caaaaggttg atttaactaa aggaaatcca ggtcttaaaa
     5041 atattttagt aggtttagga tgggatacta acaagtatga tggtggattt gactttgatt
     5101 tagatacagc agcattttta acaggagcaa gtggaagtgt tactaatgat ggagattttg
     5161 tattttacaa caatttaaaa catacatctg gagcagttga gcatctagga gataacagaa
     5221 ctggcgaagg tgatggagat gatgaacaaa tagttgttga tttatctaag attcctggag
     5281 aaataagcaa gatttctttt actgttacaa ttcatgatgc aacagaaaga agacaaaatt
     5341 ttggacaagt aagtaattct tatataagaa tagtagataa agacacaaat gaagagttaa
     5401 taaagtatga attaggagaa gattttagta tagaaacagc tatagtagta gctgaaatat
     5461 ataagcacaa tggagaatgg aagtttaatg cactaggttc tggctttgaa ggtggtcttg
     5521 ctgcattatg tggaaacttt ggaataaact tataatttca actataacaa taaactaaag
     5581 ggggatattt tccatggcta tagtattaaa aaaaggacaa aaaatcgatt taactaaggg
     5641 aaatccaggt cttaaaaata taaaacttgg actaggatgg gatacaaatt catttgatag
     5701 tggctatgat tatgatttag atgtaagtgt tttcatggtt ggagaatctc aaagagttga
     5761 aaaagatgaa gattttatat tctacaataa cttaaaacat ccatctggag cagttgaaca
     5821 cttaggtgat aatagaactg gtgaaggtga tggagatgat gaggaaatat tagtgaattt
     5881 agagacaatg ccaaagcata tacaaaagat agctgtaaca gttacaatat atgaggctgc
     5941 tgaaagaaga caaaattttg gacaagtaag caactcatat ataagagtat taaattctga
     6001 aaatgatgaa gaaatattaa gatatgactt aggtgaagaa tttagtatag aaactgcaat
     6061 tacagtatgt gagatatata agtataatgg agaatggaag tttagtgcag ttggagcagg
     6121 atttgaaggt ggcttagaag cactttgtag aaactatggc ttaaatgttt aatttaagca
     6181 atataatata ttaaatataa ataacctata caaataatgt ataggttata ttatataaaa
     6241 ttttgtggag gtttagtatg tcgattaatt tatcaaaagg tgataaaata gatttaaaaa
     6301 aatctaaccc aggactgagt aacatacttg taggtctagg atgggaccct gtgcaacaat
     6361 ctggcggagg tttttttaaa tcgttatttg gtggaggaca agctgatata gattgtgatg
     6421 catctgtatt tatgcttaat caagaaggta aattaagtgg aataaaagat ttaatttatt
     6481 ttggaaatct aaaaagtgcc tgtaaatcag ttttgcatac aggagacaat ctaactggtg
     6541 agggtacagg tgatgatgaa caaatcctag ttaatttgga taaagttcca tcaaatattc
     6601 ataaattatt gtttgtagta aatatataca attgtgtaga tagaaaacaa cactttggaa
     6661 tgatagaaaa tgcctatata agagttgaag accaaggtaa taagaaagag atagcaaaat
     6721 acaatctatc tgataattat tctgaaaaaa ctactcttat agtaggagct atatatagaa
     6781 aagatggaag ttggcaattt aaagcaattg gtgaaggaac aaaagatgcg ggtcttaaag
     6841 aagtaatgca aaatttagac aggattgagt gtgcatatgg aatttaataa tgatatcaaa
     6901 tattataatg tagataaaga agaagttaca aaagacttat ctgttaatcc tgaaaaaggt
     6961 ttatcagaat cagaagtcaa gactagaaga gaaaaatatg gtttgaatga atttactcca
     7021 aaagaagagg gtagtttttg ggatgattta aaggaaagtt taagtgaacc aatgatagtt
     7081 atcttgatta ttgcagcagt agtaagtgca gtaattgggg aaactcatga tgcaataggg
     7141 attgtaggtg ctatagcaat aggtatagca ataggtatga ttacagaagg tcgttctaag
     7201 aaagcagcag aggctctttc taagttgact gaaaacatag aagtaaaagt attgagagat
     7261 ggggaagtac atcaaatttc taagagtgaa ttggtaccag gtgatatagt atatattgaa
     7321 actggtgaca tggtacctgc tgatggtaga cttatagaaa gtataaacct taaaattaga
     7381 gaagatatgt taacaggaga atctgatgac gtatctaaaa agtgtgatgt agtagtttct
     7441 atggaagaga tagaatctaa aggagcagta gtagtacagg aaccaatacc tgcaaaacag
     7501 ataaatatgg tgtttggtgg tacacttgta gcttatggta gaggagctct agttgtaact
     7561 tcaattggag ataatagtga aatgggtaaa attgctcaaa acttatcaga aacagatgag
     7621 caaactccac ttcagataaa acttggaaat ttaggtggtt tgatagccaa agtttctagt
     7681 gcagtagcag gattactatt tatatttatg gttttccaaa tgataagtaa gaatgtatta
     7741 aatgtagata tgtctggaat attaccgttt ttagaatcaa tagacccagt taaaacagca
     7801 tttacagtat gtgttgcgtt gatagttgca gcagtgccag aaggtcttcc aactatgata
     7861 aatatgacac ttgcaataac aatgcaaaaa atggctaaaa taaatgcatt ggttaccaaa
     7921 aaagaagctt gtgaaacgat aggttctgtt tctgtaatat gttcagataa aactggtaca
     7981 ttaactgaaa atagaatgac tgtagaagtt gcatatgttg atggcagata tattgaaagt
     8041 tcagaagagg aaataaatag ttattttgaa gaaaactgta tgataaactc tacagctgat
     8101 gtagagcaca atgatggtga tattaagtat ttaggaagtg ctactgaatg tgcattgctt
     8161 ttatattaca aaaacgtaga ttatagacaa gttagaaaaa attctaatat agtagctcaa
     8221 aatcctttta cttcagattc aaagagaatg acttctgtta taggtcaaga taatcatcat
     8281 gtactattat caaaaggagc accagaagtc ttacttgaat tatgttcaca tattcaaaga
     8341 ggaaaagaca tagttccatt aactgaaaat ataaaacatg agattttaga agaaataaag
     8401 aaattgcaaa taaaatcaat gagaacttta gggtttgcat ataaagaaat ctcacaagct
     8461 gaagaagaag cagcagtaac tgctgaaagt gatgctatga atgtaagtgc aatggaaaac
     8521 aatttagtat ttagtggttt tgttggtata agagacccac ttagaaaaga tgttatagag
     8581 tctgtaaata cagcaaataa agctggtgtt tctgtaaaaa tgcttacagg agataatata
     8641 aatacggcaa gagctatagg tgaagagtta ggcctattaa aaaataatat gagagtggtt
     8701 gaagcttcat atatagatac tttagatgat gaagaattaa aacaagagat acaaagtatt
     8761 tcaatcgtgg caagaagtaa accagatagt aaaatgagaa tagtttcagc tctgcaaaag
     8821 agcggagatg ttgttgcagt aacaggtgat ggtataaatg atgctccagc actttcaaaa
     8881 gcagatgttg gtatagcaat gggtatatct ggtacagagg tatctaaaaa cgcagcagac
     8941 ataattttaa ctgatgatag ttttagtacc attgtaaaag gtattaaatg gggtagagga
     9001 atttatgata acttccaaag attcgttcaa ttccaattaa ctgtaaatgt aattgcattt
     9061 ttagtggcta taatatctca agttatggga caagagatgc catttactac aatacaatta
     9121 ttatgggtaa acatcattat ggatggacca ccagcactag cattaggttt agagccagtt
     9181 agggaccatg tgttaaacag aaaacctgtt gatagaaaag ccaatataat ttctaagtca
     9241 atggtgtata caatagtatt aaatgcattt tatataacag caatactaat gttacaatct
     9301 acatttaatt tcttaggagt tgatgaagcg cataagggaa cagtaatgtt tgcgttattt
     9361 gcttttagtg cactgtttaa tgcatttaac tgtagagagt ttaatgcaga tagtatcttc
     9421 cctaatttta cacataacaa attagcacta caaataatag tgttgacagg aattgcacaa
     9481 gtaatattta ctcagctatt ccaagatttc tttaactctg tagcaatgga ttttatgaca
     9541 tgggtaaaag ttttatgtgt agcagcaagt gtaattgtgg ttaatgaagt tgtaaaatgt
     9601 ataataagac tggtaaaacc aaaaaagact gcttaaaaca aattttttag aagaaaacag
     9661 actgactcaa aatatgaatt ttgggtcagt tctgaataaa catttaaatt gggaggatag
     9721 ttatgggtga ctcaaaggta tttgaaaaaa tattctccag ccaatcagat agaggaaatt
     9781 acactccttc aaagggatat ctaagttatt ttatttcgta tattggttta gaagatgaag
     9841 ttttgtacaa tctcgagata tttaaaacaa aacaaaatat tgatagcaaa aaagatattg
     9901 ctttatttac tgatgttata gcaaatccta gtgattttga tattataaat tattttaaaa
     9961 gtggacttca aaaatataga actagcatgg aagatgtaga tataaatatt ttgggatttg
    10021 aagagattga ttataaaata aagcaagcaa tggatagagt gttaaaagaa gaggaaaaag
    10081 aatttactaa tgatagagtt aaacaaaatt ttatagtgaa aataatggca tggataaaaa
    10141 tttatatcgg tgctttagat ataaataaaa atgaagctcc aaaagtaata ttttatggag
    10201 atataaaaaa acatgaagtt tatttactct taatattata cttggcaggt tttgatgttt
    10261 tatatcttaa tccaaattca aagagtaata tagatatttt aaaatcagaa agatacaata
    10321 tagagtttga agaagccaac ataatagaag aaaaaatttc ttttgaagaa agggttattt
    10381 taggggaaaa aatagataaa agttctgtaa aaaaagcttt tactgttggg gcagaagcat
    10441 caaagcgtat aagtgaggaa ttgttaaatg atgcaggatt tataaaacct tggcaactcc
    10501 aagatagaaa aataaaaaat ctacttctaa gttcaactgt tgatgaaata tcaatatact
    10561 ggaatcaacc acttaaatta agaccaggat ttaagtttaa tgatgctatt gtagaagctc
    10621 caaattttct ttctaagatt aatggaatat ataacgataa gaatgaatat attaagtttt
    10681 tagatttatt aagagattcg gaaagttcaa catttattga atttaatgga gatgtagata
    10741 gattttcaaa agcttttaca agagaagctt ttagtttatc ctttttattg gattcaaaag
    10801 gtgcaataga taaaaactct gttttaaata ataaagatta ttccatatca acattagcat
    10861 tgaatcaaca aattatgatt ttagagaaag tggaagagtt gttagaagga agtatgtttt
    10921 tgaatggttt aagtggagaa gacaagataa aaggtctatt tacagtactt cacatggata
    10981 agaaatttgt tcatatgatg aacaatttcg attactcact tataaaccca aaattgatta
    11041 tatacatgta caagagtatt gtatttgata aagaaatagt ttttcttatg cttttactta
    11101 gtaagattgg atttgatatt atcatattat gtccaggagg agaaaacaat atagagaatg
    11161 ttataaataa ccaattgatt gatgtacaca gattggataa aatggtatat gaccttaaat
    11221 taaattcgct tgaaaatgat atacctttac ttaaaaaaat ttttggaaag aggagacgat
    11281 tttagatggg gataaatata aatagttttt caaaagataa gaactctgta gaggttactg
    11341 agaatttgcc tacagcagtt caagaagaaa acttcgatat aatggaatat acaaataata
    11401 aaaaaaatga actgagaaag tctaaggaag ttgaggcatt gacatctctt atagaagtag
    11461 aaaatccaga tacgatttta cagtttggta ggaaagcatc tgaaggagta gcaagagttt
    11521 ctgatagcct tttaaataca ataaaattaa atagaaatga agaaaattct aaaatgctgg
    11581 ttcatttaac taaaataatg gacaagtttg atttagacga ttttcaagaa actaaggaac
    11641 caaatttcgt tcaaaaactt ttcaaaaaag ctaataatgc cattgaaatg atgtttcaaa
    11701 agtatgaaac attgggagga gaagttgaga aaattcaaat tgagcttgaa caatacgaaa
    11761 gagatatagc actttctaat aagcaaatag gtgctatgtt aaatgaaaac tttgagtttt
    11821 acaatgaact tcaaaaatat attgttgctg gagaaatggc aatagaagaa atggataatg
    11881 aaatactacc tttctttaaa caaaaatcag agactagtgg agaccaaatg gatgttgtca
    11941 attatcaaga actattaaaa gtttatgata tgttaaatca aagagtctat gatttaagga
    12001 tagcagaaaa tatagctatc caaacaatac ctatgcttag aggtatgcaa cataataatt
    12061 atggtttaat tagaaaaata aatagtgcat ttgtcgtaac tttaccagta tttaaacaat
    12121 gtttatctca agctatatta cttaaaaagc aagaattaca agcaaaatct ctaaaagcac
    12181 ttgatgacaa aactaatgaa ttattgctta gaaatgcaca aaatgtaagt actcaaagtg
    12241 cacaaatagc tagaatggct ggaacaagtt ctgttcaaat agaaacattg gaaaaaatgt
    12301 acaatactat taaatctggt atagatgaaa ctatgagaat agaagaaaac aatagagctt
    12361 taattaagga taatacaaag agattggaag aattaaatac gactataatt tataataagt
    12421 agtattatat taagggctaa tttgtataaa gttggccctt tctatgtata tgaggaggct
    12481 agacattgaa atatttcgat tatatctgca aagatgattt ggagagaatt tttttgaagg
    12541 agccagaaga ttttagtgct aagactgaaa aagatgtgtt gaaatatgca ctgggcgctt
    12601 ttttatacgt tccagctact caatataata tgatttataa gagtattata ggggatgtta
    12661 agggagttag accattagct atttgtttag aagatgctgt tggagtaaat ggagagttag
    12721 aggctataga aaatcttaga ttaattttaa aaaatattag caatgaaagt ataactaata
    12781 aagatggaat accactaatt tttgtaagaa taaaagatgt ggagcaactg ttgagaatta
    12841 aagagattat aattaaaaat agacattcta taacaggaat attaattcct aaagcaaatt
    12901 cggagttaat agaaaattgt atagaagctt tagattctat gaatcttcaa gatatgtatg
    12961 ttattccgat aatagagaca aaagaattta tatataatga aaaaaaagaa cttagtttta
    13021 ctaatttgta caatgctatt ttaagacata agtcaagaat attaagcatt agagtaggca
    13081 taactgatat attagggatg tatggtataa ggagagataa gaacttctct atatataata
    13141 atttgatttg ttcttcattt atattagata taatcacata tcttcaaaga ccagagttag
    13201 atatacctat aagtggtgga gtatcagaat tttttgatat gacgaataag gatataagaa
    13261 ataagtatat agaagaaata ttattggata aatatcatgg attaattgga aagaccgtaa
    13321 ttcatccaat gcaaattcaa attgtacaag cgctatctac agtatcatat gaagatttta
    13381 ctgatgcttt ggatatactg gatagtacag acagtaagta tggtgtgagc aagggtgtat
    13441 taggagagag aatgaatgaa acaaatccac attttttatg ggctaaaaaa acattgattc
    13501 tatctaaaat atatggtgta ttaaataaag gagtagacta tgaagaattg cttaaatttt
    13561 aattgtgaga ttgacattat tgataatcca ttgaatttag aactaaatga ttttttagac
    13621 gtaggaataa gaaataatag caaaagacgt tttttgttta tctcaaagaa actcggtaaa
    13681 catttagcat gtaagccaag tgagatggat aatttgggaa aattaatggc tacaatttat
    13741 aatgaaaaaa ataaggaaga atcaaatggt actgttatag cttttgctga aactggtaca
    13801 gctgttgggc atagtttttt tgattactta tgtggagatt atgaatttat tcatactact
    13861 agagagcagt ttgacgagtt agaaaatctg gaatttttag aggaacattc ccatgcaaca
    13921 gaccagaatt tatactttgg tatgcttaac aactttaaat ttggagatga gataatattg
    13981 gttgatgatg agattaccac agccaataca tgcatgaata taattaggaa aattcaaagc
    14041 atttatccta aaaagaaata cactatatgc tcaatactca attgggtaag tgatgaaaat
    14101 ttaagtaaag ttactcgttt agaaagagag ctagattgta agatagattt tgtatactta
    14161 tttaaaggaa actttaaatt ttatatagat gaagatatta tttcaaatta caacgataat
    14221 tatagtatta ctaaattaga gactatttca agtgataaag taaatttagt agtaaatcat
    14281 atttatgttg atttagaaga ttatattgga aataagaaat atgtaaaata tacaggaaga
    14341 tttggaatta atagaagaga acaatttaga ttaaaagaaa tcgttaagag agaaagtaaa
    14401 aaaataacta tggccagtaa agaatcttta aaaaatgaaa aagaaaagat tctattttta
    14461 ggtactgaag aatttatgta tatacctatg ctgtttgcaa aagaaaaaga aaatcaatat
    14521 gatatatact atcattcaac aacaagaagt ccaattatta atattgataa gaataattat
    14581 cctattaaaa gtaaatttat gctaaagagt ttttataata tagatattca aaattatatt
    14641 tacaatatag ataaacataa tttttctaag tgttatttat ttgtagagct gaataaaagt
    14701 gaaaattctt atctagaatt tattgatata attaaaaaaa caagtataaa agaattaact
    14761 atagtatgtt gtagctaaag tgttttaaca ggataaaata tatcacgatt ttaagatagg
    14821 agttgagtca tatgagagat tttagcacgt attctaaaga tgatgttatt tttttattaa
    14881 aagatatatc aaatttaatt gaagaagaag gaaataaaga aagagaatta aaaatacaaa
    14941 atggtagaca ttattcagaa atgataccaa tagagtatga agttagtgaa gattatctga
    15001 atttatatca tgagaaacta agagaaaata aagataaact tgcattttct ataggagtta
    15061 tgtgtgaaaa aataattaaa aaaaatggaa atgatgtagt actagtttca cttgctagag
    15121 caggaacacc tattggtatt ttggcaaaaa gatatataag aagcaagtat aatgtaagtt
    15181 tacctcacta tacaatctct ataataagag ataagggaat agatatgaat gcaattgaat
    15241 atatagtaaa gaatcatccg agctcaaaaa ttcaattttt agatggatgg actggtaaag
    15301 gaactatatc aaaagaactt gaaaaagcat gtgatgaact taatgttaaa tttaaaaaat
    15361 attttgactc aacacttgct gtattagctg accctgctgg atattcagga ctttatggaa
    15421 ttagagaaga tttcttaata ccaagtgcat gtttaaattc aacagtttct ggtttagtaa
    15481 gtagaactgt actaagagag gatttaatta gtaaaaatga ctttcatgga gctaagtttt
    15541 atagacattt aaaagataaa gatgaatcta tgaactatat cgaaactata gaagaatgtt
    15601 ttaaaaatca atttaagaat atatctgatg aagttgaaaa ctgggaaagt gacattataa
    15661 caagagatgg atactttgat gttttaaata taaaagaaaa gtataacata acagatatta
    15721 actttatcaa accaggtgta ggggaaacga ctagggtttt acttagaaga gttccgtata
    15781 agattcttgt taaagactta aatgataaat ctttagacca tatattcata ttagctaagg
    15841 agaaaaatgt tgaagttgaa caaatggatt taaaagccta taaatgttgt ggaataataa
    15901 aaaatatgaa agatatttag gaaatatatt agacaggaga atattgaatg attgtttttt
    15961 cagatttaga caggagtatc atttactcca ataaattttt aaatgctgat agtaaatatg
    16021 ctaatataga aatttatagg gaaaaagaaa tatcttatat atctttagat actataaatt
    16081 taataaagca aatacaatat tatggtatgt ttatacctac aactactaga acagtggagc
    16141 aatttaagcg tatagaattt aataaatatg ggatttattt tccttggagt ataacttcaa
    16201 atggaggagt tatacttaaa gataatgaaa tattgaaatc atggagtgaa aaaatagata
    16261 aactaaaatc tgattatgag cccattgaaa gtatgattca taaatttaaa gactatttga
    16321 atgtagatgg aataactaat tttaaagttg cagaagatac atttttttat atagttgttg
    16381 atttatcaag atttaatttg gattcaatca aagaatatac aaatatattg gaatcaaaaa
    16441 attggaagtt ttatgtgagt ggcagaaaaa tatattttat accaaaagaa atttcaaaag
    16501 aaaatgctat aaaatacttg actaaagaat taggaataga atatttttat gcagttggag
    16561 attctattat ggactatggt atgcttaata tctcaaataa atcctatgta ttgaagcatg
    16621 gtgatataaa taaaaatgaa atagaaaatt catttatatc aagttctttc aatggaatga
    16681 gtggaactga agagatacta tctaacattt tagacgagaa ctgcctactt aatatataat
    16741 gactgatata taaataataa actagaaaaa tctgaaataa attatagtaa agtttatcat
    16801 actaatttat ttcagatttt tatcaattta tatttaagta agaactcaat atgttaaaat
    16861 gaaggtggag tcattgccca gactgagata catacctcat catcataatt ttcatacaca
    16921 tgtggtatag tactgttaaa ataaaaacta tctccttcct ccaatagata ttccttattt
    16981 ccaagtgtta tcttcatttt accttttatt atatagccac attcttctcc ttcgtgtgtc
    17041 acaaattcac tgtttttgtg tgtatgacca tctagtgtaa caagtataaa ttctattttt
    17101 ttcccagata aattaggaac aagaagttcg taaaattttg tagaatcatt agttactatt
    17161 ttttttcgat tatttttctt tactactata tcagagtctt ctcttccaat ctcttcaaaa
    17221 aaataaccta tatttatatc aagagctttt gatattttcc acattgctac aatagatgga
    17281 acaaccatat tacgctcaat ttgacttatt aagcctgtac ttaaatctga attttttgct
    17341 aaagtagaga tacttatatt tttagatttt ctaagagatc taattttgct tccaacatct
    17401 atattcatta gatacaaacc ccctcagaca tgattataac atataattta taaagattaa
    17461 taaaataaaa aaaaagtttt acaatacaag tattttttat gctatattga attttctgaa
    17521 aagatgcatt ataatagtat taatattcaa tatattgaat attgataacg atattttaat
    17581 ttaatgaaat ggaggtaatt aagatgaaga gttttgtaag tcctgataat atttgggtat
    17641 tatgggcagt tgtaactgga tgggcagcat ttagtattta tttggaacaa aagtacaatt
    17701 gggcatcaaa agtgtcggga gcaataatag ctcttgtagg agcaatgtta ttatcaaatc
    17761 taaatattat accagtagag tctgttgtat atgaccaagt atggggatat gttgttcctt
    17821 tagccatagc tttattgtta tatcaatgta acattaaaaa gatatggaaa gaaagtggaa
    17881 gattgctcat tatatttctt gtaggttctg taggaactgt acttggagct atgattggat
    17941 ttttagcatt aaaaaatgta gtaccagatt taaatattgt tgcagctatg atgacaggtt
    18001 cttatatagg tggaaatgta aactttgctg ctatgtcagg ggcgtttgat gcgccaggag
    18061 aattagtatc agcaacagtt gtagcagata atcttttaat ggcattatat ttctttgtct
    18121 taatagctat accatcaatt ggatttttta gaaaacattt taaacatcca catgtagatg
    18181 aaatggaaag tataggtata actgaaggag aaacagtagc agcaaattat tggggaagaa
    18241 aagaaatatc tttaaaagat atagcaatag ccattggtag cgcttttata attgtcgcag
    18301 tatctgtaga actatcaact tggtttaaag ctataatacc attatcaaat ccttttttag
    18361 caatgttaaa tactttattt ggaaatcaat atctaataat aactactttg actatgttgt
    18421 ttgccacatt tatgcctaat ttctttggtg atataaaagg agcacaggaa ttgggtacat
    18481 ttttaatata tatattcttt gttgtagtag gtgttcctgc ttcaataaca ttaataattc
    18541 aaaaatcacc attactactt ttatactgcg gaataatggt actaataaac atgctagtta
    18601 catttatagt tgcaaaaata tttaagttta gtttagaaga agctattctt gcatctaatg
    18661 caaatattgg tggtcctaca acagcagcag ctatggcaat atcaaaagga tggtctaagc
    18721 tagtagggcc aatacttata gttggaacat ttggatacat agtcggtaat tattttggtc
    18781 ttttagtagg aaatattttg atataatttt acgtgaaaaa aagttgtttt ttagaaagat
    18841 ttttatttaa ttggaggttg ttatgatttt cgatggacat tcagatactt gggcagatgt
    18901 aacaataaga aggcttaacg gggaaaaaga tgtatttaga agaatccatc ttgataattt
    18961 taaaagagca aatatagaag gagctatttt tgtaatatgg atagacccac catatgataa
    19021 agagcctgaa aaaagagtta aacaaattat aagctctata aaagatgaaa ttgaagatat
    19081 gaaagatgtt gtaaacatag taaaaaaata ttcagatata gataaaggta taagtgaaaa
    19141 caaaataaat attttaattg gtcttgaagg attaagccat attggaagaa atatagattt
    19201 actagattat ttttataaag aagttggtgc aagacatgca tcattaactt ggaatgaaca
    19261 gaatgaactt gctacaggat gtttagggga tgaaaatcgt ggtttaactg aaataggtaa
    19321 aaaagcagtc aataaaatgg aaaaattggg catgatagta gatgtgtcac atttaaatga
    19381 aaaatcattt tgggatttaa tgtctgttgc aagtaagcca gttatagctt ctcattctaa
    19441 tgctaggagt ttatgtgatg ctaaaagaaa tcttacagat aatcaattaa aagaaatttc
    19501 aaatacaggt ggattagttg gaataaatag ttttagagga tttactaata gtaatcctaa
    19561 gaagcaagat ttaatacatt tggttgacca tatagactat atggtaaatc ttataggtat
    19621 agaacatgta tcttttggtt ttgattttag tgattactta gggaaagaga ctataggttc
    19681 ttttactgga aatgctagtg tgccaagtgt agatggtctt gaaagcacac atacagcaca
    19741 gaacatagta gtagagcttg aaaatagagg ttataaaaag aaagatatag agttaatctc
    19801 tagtggtaat ttttataggc tctttaaaga tatactaaaa taatataata aagaacttaa
    19861 atttataaaa tagtatattt atacaaataa tatctacata tttaaattgg cgttcataat
    19921 ttattaaatt aaattttaat gttactagaa gtttcaattc tagtaacatt ttttatgtta
    19981 aaaacagata tagatatata ttgacaatga taattattat tgataaacta taaaagtgaa
    20041 aatgataata attttcattt taattaataa aagattttta aggagggaga atgaagaaaa
    20101 ggtatttagt cataggaata ataattttgt cttatttttc tttatttata ggagctgaag
    20161 atataaatat aatgcatata tttgccaaaa atcagcataa acttatgata tttatcatga
    20221 gtagaatacc aagattaata agtatattga ttgctggtgt aggaatgagc atagcaggtc
    20281 ttataatgca acagataagt aagaataaat ttgtatcacc tacaacaggt gctacaatag
    20341 atgcagcaca atttgggata gtaatatgta tgcttttagt accaactgcc tctattttta
    20401 caaagacaat aatagcattt gtattttctc ttgtagggac ttttacgttt atgaaaataa
    20461 tagggaagtt acaatttaaa aatataatct ttgtaccatt agtaggtata atgtttggaa
    20521 atataatagg ttctatgacg gattttatcg cgtataaata cgatttgagt caaaatgtta
    20581 gttcttggat gcaaggtgac ttttctatga tacttaaagg aaattatgag atattatata
    20641 tcacaatacc ccttataata ttagcatata tttatgcaaa taaatttact gttgttggta
    20701 tgggtatgga ttttgcgaca aacttaggtc ttagttacaa aagaattgtc aatataggtc
    20761 tgataatagt agcacttgtt acagtatgtg tagtcgttac agctggtaat atccctttta
    20821 taggtctaat agttcccaat atcgtatcct tgtatatggg tgataatata agagcaagca
    20881 tatggtatac tggtttactt ggagcgatat ttgtacttat atgtgatatt tttggaagaa
    20941 ttattattta tccatatgaa atatctatag ggcttacagt tggagttata ggaagtatac
    21001 tattccttta tttaatatta aggaggaatg taaatgaagc ttagtctcaa tcaaaaaatt
    21061 tactttgtaa gtatattact attcatatca atagcacttt ttataattta tggaatagac
    21121 atgaatcatt tagaatatgc attatcacaa agaataccaa aaatatttgc tatggtatta
    21181 ggtggaggat gtatagcatt tactactgta gtgtttcaaa caattacaaa caatcaaata
    21241 ttaacaccaa gtgtactagg tttagattca ttgtatgtaa tgattcaaac tataatagta
    21301 ttcatatttg gttcaagcag tagtctgatt ataaatgaaa attataattt tattattaat
    21361 gtagctatga tgattggagc ttcattgtta ttatataaga cgttatttga aaaaaataaa
    21421 aataatattt tctttttaat cctagtagga atgatatttg gaaccttatt taaaagtgca
    21481 acaacattta ttcaggtaat gatagaccct aatgaatttt tagctttaca aactagtata
    21541 atggcaagtt taaacaatat aaacactaat gtattgttaa tagcatttat aataattatt
    21601 gccataatac cttttatata tgatgaaata aagtatttag atgtattgtc gttaggtaaa
    21661 gaacaagcaa ttaatttagg tgtagatttt gataaagcag ttaaaaaaat gataatatta
    21721 atagcaattt tagtctcaat atcaacagca cttattggac ctatgacatt tttaggactt
    21781 ttacttgcta atataacaag agaaattttt aaaacatata agcatacata cttgatttcg
    21841 ggttctatgt tgatagggat gattacattg ataataggtc aattttttat acaacatgta
    21901 tttaagtttg atacaacttt aagtgtagta ataaatttta taggaggaat ttactttatt
    21961 caattactat taaagggggc aaatagatga tagagataaa aaatatattt aaaagatata
    22021 agaataaaaa tgttgtagat gatgtctctt ttagtataga aaagggaaag ataacatctt
    22081 ttataggacc aaatggagct ggaaaaagta cagtactatc aatagttaca agacttatag
    22141 gaggtgatgg tggagaagta ataatagaag gaaaaagctt gactaattat agcaataaag
    22201 aattagcaaa aaaaatagct attcttaaac aatctaacaa tataacttta aagcttacaa
    22261 taagagaatt agttggattt ggaagatttc catatagtga aggtaatcta actaaagagg
    22321 atgaaaatta tattgatgaa gcaatagaat atatgaagtt gactgatata caacataagt
    22381 atttagatga attgagtgga ggtcaaagac aaagagctta tatagcaatg gtaatagctc
    22441 aagatacaga gtacatatta cttgatgaac cactgaacaa tttggatatg aaccattccg
    22501 tacagatgat gaaggtactt agaagtcttt gtgatgagtt agataagact atagtattag
    22561 taatgcatga tataaatttt gcatcatgtt attcagataa tatagttgca ttaaaaaatg
    22621 gaaaagttaa aaaagtaggt cgtacagatg agatagtaaa tgaaaaagtt ttagaagata
    22681 tttatgagat gaattttaac attaagaata taaatggaaa tcgaatctgt atttattttt
    22741 aaaatattgt atatgaaaat aaacttgcta tatgattttt tataaagttt ttaaattaaa
    22801 ataaagatta ataggagaga ggaaaatatt gatatgaata aaaaagcagc aatagtagca
    22861 gcagtagcta ttataggatt agtgacagtg tttgcattag gtggaagtaa aaagaatgaa
    22921 tcaaaaacat cagaaaattc aaataatact atgaagataa ctcataactt gggagaaaca
    22981 gatgtaaaat taaatcctaa aaaagtagtg gtatttgatt attcggcttt agatacaatg
    23041 gatgcattag gtgtagctga gaatttagta ggacttccaa aagcgagttt accagcatcc
    23101 ttagaaaaat ataaggatga caagtatgca gatttaggag gattaaaaga accagattta
    23161 gagggtataa agtcggcaaa tccagattta attataataa atggaagaca agaagatttt
    23221 tatgagcaat tgtcaaaaat agcaccaaca ataagtacaa gtaaagatga taagaagtac
    23281 ttagaatctg ttaaaaataa tatagacaaa atagcaaaaa tatttggagt agaagaaaaa
    23341 gcaaatcaag aatttagtaa aattgaaaag aaaatagaaa ctttgaataa aaaagtaaca
    23401 gataaaaatt taaatgcttt aactataatg gtaaatgaag gtaatttaag tgtatttggt
    23461 gaagaatcaa gatttagtat attatacaat agttttggat ttgaaaataa agataaaaat
    23521 ataaaagaat caagtcatgg acaaaatatt acttttgaat atatagctaa acaaaatcca
    23581 gaagttatgt tcgttataga tagaggaata gctactggca gtgatgtaaa agaaagctca
    23641 actgcaaaat ctgttttgaa caatgatata ataaaatcta tggatgcata taagaatgat
    23701 aatataatat atttagattc accaacatgg tatgtaaatg atggtggtct aacatcttta
    23761 aataaaatga tagatgatgc ttcaaaagcg gtaaattaat aatccgatat aatcaaaata
    23821 tattttttat aaaatgatta tcaaataaac taggagtttt taagaactcc tagtttattt
    23881 tttgcataaa aaagatatag tttaaacaat aatattatct ataataagat
//
LOCUS       DAJMZY010000060        23664 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.060, whole genome shotgun sequence.
ACCESSION   DAJMZY010000060 DAJMZY010000000
VERSION     DAJMZY010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 23664)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23664)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23664
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.060"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            328..1179
                     /locus_tag="OE968_002265"
     CDS             328..1179
                     /locus_tag="OE968_002265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3100 domain-containing protein"
                     /protein_id="HCP7219542.1"
                     /translation="MEINKKHFIQVFLTCLILVVICEFIGQRTIAIGKASIVLFPMLY
                     AVIIGLIITPDLLGKKIKALKKVVGEKEINIAGEVVGIALVMLGIKYGTTVGPNIDKI
                     IQAGPAFIAQEFGHILAPIVALPLALMFGMKREAVGATASISREPSLGVISEKYGINS
                     PEGSGVLGTYLMGTVLGTIYFSVLGSISIYSGLHPYALGMACGVGSGSMMTAAAGSLS
                     TMVPPEMADTILAYAATSNMMSSITGIIFLVFVSLPFTNFMYKILEPKFSRNKKTKEI
                     KSTEGEC"
     gene            1183..1653
                     /locus_tag="OE968_002266"
     CDS             1183..1653
                     /locus_tag="OE968_002266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219543.1"
                     /translation="MFANLNLKKSSYQLLVMSVIGVIILIGQRISVGTSIVTALPGMV
                     MLILAAMAAMIIKDLFPKSIFPAFGFATIIGLLLSMPYSPTSEVFLTNTNNINFMAIT
                     TPLLAFAGISVGNKIEALKEMSWKIVIISLIVFTTIFFACASIAHIVLSIQGKI"
     gene            1666..2976
                     /locus_tag="OE968_002267"
     CDS             1666..2976
                     /locus_tag="OE968_002267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HCP7219544.1"
                     /translation="MNKEQLKSLVIKTIDENREKILKIGQGIYKNPEYGYKEFKTTEA
                     VSNFFEQELNLSVEKNIAVTGCKADANSSKKGPHISILGELDGISCKEHKDANEIGAS
                     HTCGHNIQIAGMLGAAVGLVKSGVLEHLDGKVSFMATPAEEFIELEYREQLKKEGKIT
                     YFGGKQELIKRGYFDDIDISMMFHASDLGEDKALVGPESNGFVGKKVKFIGKESHAGS
                     APHDGINALNAAMLAINNVNALRETFKESERVRFHPIITKGGDIVNVVPADVHMESYV
                     RARTINGMIDANERINKALMAGGMAVGADVEITEIPGYLPILRYKSLDNLFKNNLEDL
                     GLKGKVIDGGDFTGSFDFGDVSHIMPTLHPMIGGVKGALHTRDFEIVDEDLAYIIPAK
                     AMALTVVDLLFDNAKDAKDILDTFTPVMTKEEYLTFLEKHDKTL"
     gene            3188..3934
                     /locus_tag="OE968_002268"
     CDS             3188..3934
                     /locus_tag="OE968_002268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HCP7219545.1"
                     /translation="MFNAGNRIINTWLYPIQDGFVLIDTGYENGFKHFKKRISKFNIK
                     IKDIRYIFLTHAHDDHVGFLNQILDESPNTKIVMHDKALEILYKGQNSFIGGCTSRTA
                     FLFCQIMKLFGKGEHSFSPLKQEFEKRCILVSDKNRKEIEKELNGKIIDTPGHTADSI
                     SLLIDEGVLFCGDSAMNGFPSTHKITIFAESKLEFIQSWKTIINTKPKMIYPGHGKPF
                     EYSKLEQNLIYVNKINLYPLHNSKDIHRFL"
     gene            4296..5837
                     /locus_tag="OE968_002269"
     CDS             4296..5837
                     /locus_tag="OE968_002269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbgT family transporter"
                     /protein_id="HCP7219546.1"
                     /translation="MNDNVVKKKNFFDRTLNRIETVGNKLPDPVTIFLGLCVLLLILS
                     SLVGSMGISVVHPGTGETITAVNLLTVEQLQILLGNIVSNFQGFAPLGLVLVTMIGAG
                     VCDKTGLMTATIKASVSKIPETRVTLVVMTIGMLANIASDAGTILFPPLAALVYLGVG
                     RHPLIGLFSGYAAVCLGFAANIMISVNDILAASFTVPAAQMIDSGFQANATMNLFFMI
                     ASTFVLILLATWVTEKIVAPRFGKYEGNAELDVDGSLSDVEKKGLKKAGISILIYVAI
                     IVALSVIGKKPFLADPETGDLLSNNAPLMKGMVPIIALAFFIPGVVYGKTIGKIKKDK
                     DVVSIMASAMSDMGGYIILAFAASQFLQLFTNSNLGLILAVKGGEFLKSAGINGPLLL
                     IGFIILSCFINLFIGSASAKWAILAPIFVPMFMMVGYNPALTQMAYRIGDCITNPLSP
                     LFPYFPIILAFTRKYDKDAGMGTVIANMIPYSISFLIVWTILLILFMVFNIPLGPGIL
                     PSYSM"
     gene            5872..6978
                     /locus_tag="OE968_002270"
     CDS             5872..6978
                     /locus_tag="OE968_002270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HCP7219547.1"
                     /translation="MLDKNRLINNFMDMVRIDSPSNQELEMSKWLVNYLKERNIDAII
                     DDAGEKYGGNTGNVIAYIKGEEGSRPLCLCAHMDQVQPCLGVKPILDGNVVRSDGTTT
                     LGADDKAGIAAILEALEHVITEKIPHRDIYLCFTICEEAGMHGVKNFNPDNLPCKDMV
                     ILDSGGAIGSIAYKAPAQQSIKISFHGKKAHAGIEPEKGLNAILVASHAISNMHIGRI
                     DSLTTSNIGKIEGGGATNIVTDKVTLTAEIRSHIPETLEYELNHMEKCCKDAASKFNT
                     TYTFEHSMSYPSFELSRDSHVFKLSEEAIRQVGVVPNPMVIGGGSDANILANLGYNCA
                     ILSLGMYDVHTVNEYVNIDELYDTAKIVYHMIKL"
     gene            complement(7309..8595)
                     /locus_tag="OE968_002271"
     CDS             complement(7309..8595)
                     /locus_tag="OE968_002271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HCP7219548.1"
                     /translation="MIVGIIGPSDSGFKIKDDLKQIDSDLKTKIYVREKVVDTIEVIS
                     KCEDECDAIIFTGCAVYEFIKSKYEISKPHSFVPRSGTSIMKAFWAIKSANIKLDKFS
                     IDVVDRYVVEDALKEFDIKATSVFCNPFSLEVGESELVEWHIKLFEENKTDIMLTGFG
                     AVYNELKERGYPVFRLQATIQLIKESYDKVKSEYALSKARFSQIAVEILSLIDYKEKI
                     DNYYSDMIKKSDMDKLVVNYVRSIQGSLFLLGRNDYVVFVHKGVADNEYNYDKLFNLK
                     REIKDMGFSLSIGIGTGVTAYQAENNAHKALRHSIDSKEIGIYLVDEDENIRGPLASE
                     NELNYSLMLSDEKVIEISKKTGMSCESVAKIIAINENRKSKIYDSKELAEYLNVSERS
                     ARRILNKIVNAGLGRICAKETSIGGGRPKNITEILF"
     gene            complement(8718..11816)
                     /locus_tag="OE968_002272"
     CDS             complement(8718..11816)
                     /locus_tag="OE968_002272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HCP7219549.1"
                     /translation="MDVINLIDELDEIVYVSSLDTYELLYINEIGKKAMGLNDISHLK
                     CYKALQGKDSPCEFCTNSILKEDEYYIWENTNTRTNRHFILKDKLIKWEGKHARLEIA
                     LDITEKEDISKSIAEKLEIKELLVGCIKHLITESNFSDAVNLVLTNIGKFHKADRAYV
                     FEVSEDRTKVTNTYEWCNEGVDEQKQALTNLDINELKNWFLLFEQKGFVIIDDIENIK
                     EEQPIEYEILKPQKIESLMTSSLKQDDKVVGFIGVDNPHKAVGDTSLLTSLSYFLLTE
                     MKKRKVENKLNYMSYYDFLTGAYNRNKYIKYIDNFQKGKVKSIGVVFVDINGLKDIND
                     NFGHANGDSAIVSACVIIKKYFHSYNVYRIGGDEFVVLCEDISKQLFEELVSWLSEEF
                     KDEMIYSVAVGSIWSDDNIDIHKLIKVADERMYQDKKRYYNKNKLRNNEMKVISDLAD
                     STNNILFKHKELVDKVYFDDLMIKGYSKAYEKLAYNTYDIILSICIDTNLITPIYQSE
                     SNIFSFPIKENLEKTFSYIKKYLIHPDDIILFNDNHLLKSLDSLNNSKQDDLELNFEY
                     RRLGIDKKYYWALIYMLKISSKNKLGEKQTHILVAIKNIDYLMQLHKNQKDTLTGLYN
                     YESFCEQISLMLKRYPDKRYAIIMMDIDKFKVINDIYGVRGGDKALIYVAELIQKNIG
                     SNGICCRMYADVFCIFYESYSDRDIHKVIYKIKNSLNRKKFEYMLVPCFGVYRILDNH
                     IPITNACEMAGYAHKKVKKQSINNYIFYDDTIRNDALEEKQMEREMEYALENGQFHVY
                     LQPKYNLNANKIVGAEALVRWVHPEKGIIPPIKFISLFEKNGFIIRLDMYVWEQVCSL
                     IRKWIDLGEEPVPISVNVSRLHLHNPHFKEIVLSLINKYSIPKSFLELELTESLFIKN
                     IKLFTKIIADLRMDGIVLNMDDFGSAYSSLNMLKNINIDTLKIDCGFFNEEGITDREK
                     IVLKHTIAMAKDLDMDVVAEGVETKEQAEFLVSLDCVVIQGYYYCKPIPSSDFEKLLY
                     QK"
     gene            12541..12693
                     /locus_tag="OE968_002273"
     CDS             12541..12693
                     /locus_tag="OE968_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219550.1"
                     /translation="MKIFSFLLFVVGICFCIAGFMGHSSAFSGATLSFFATTMIAVRQ
                     VKTKKK"
     gene            complement(12986..13690)
                     /locus_tag="OE968_002274"
     CDS             complement(12986..13690)
                     /locus_tag="OE968_002274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCP7219551.1"
                     /translation="MEIKPLVLIVEDDKPICKFIKVSLETQNYRCVETDNGGTAISLI
                     HSLDPDLIILDLGLPDIDGIEVIGRVRACAKTNKIIVVSAREHERDKVEALDGGADDY
                     LTKPFSVTELLARVRVALRNKAQQDNINNDAPKSFEVKNLKIDYENHIVSINGEEIHL
                     TPIEYKIIELMSKYSGRVLTHKFIIDKVWGNYYESENQSLRVFMASIRRKIEKNPAQP
                     EYILTEVGVGYRMADE"
     gene            complement(13681..15288)
                     /locus_tag="OE968_002275"
     CDS             complement(13681..15288)
                     /locus_tag="OE968_002275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4118 domain-containing protein"
                     /protein_id="HCP7219552.1"
                     /translation="MKKERLQHEDLKEYDYDEDGYLSKKIIIKDFIKTILVMTIATGI
                     SVVFEKVGFNESNIILVYILGVLFATSITYGYFFGILSSVIGVLSFNFFFTHPLYTFL
                     AYRKDYPMTFCIMLMAAIITSTLTSRIKREVRLSHKREKMIRLLYENNKTLLKAKNKN
                     QIIEFCGSNLVNILNRTVIVTIADENNNLGKPSIYICNNDGSENIFHSVLEKEAIKEA
                     FRTGNPVGIGTKYCKNSSAYYFPIKGQESNVLGVIGVACFKIDIITENEKILLEAVST
                     QVALAIDRENLFEKNKKANLEAERERLRGNLLRSISHDLRTPLTSILGSSSTILENDD
                     VIDKETRVELLKNIYEDTSWLTHSVENILSMTRIDEGKLDIEKRPEVVDEIIAESILR
                     VKKFANSRDIKTNIPDEIIIVHVDVLLIEQVLVNLIDNAIRHTPKNSKIELTVKKESN
                     QVLFEVADNGKGIPNEDIGNIFNRFYTKNKSRNLERRGIGLGLEICKSIVEAHGGEIV
                     AFNNPSGGATFRFSIPMYDEEGKDKWK"
     gene            complement(15542..16720)
                     /locus_tag="OE968_002276"
     CDS             complement(15542..16720)
                     /locus_tag="OE968_002276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219553.1"
                     /translation="MEKLSDKRRVKAVSMETFVFIVLLAVGFGYVGSIMGAGMMFKVI
                     MSTAHALLLDTVFLIMAMAVLAGALSALLSEFGVISLVNKIFKGLMRPIWGLPGASIA
                     GVVATYLSDNPAIIPFAKDKTFTQYFKKYQVPALCNLGTAFGMGLIVTTFMIAQGKEY
                     VLPAIIGNVGAIIGSIISVRIMLTFTKKYYNYDPKNDTEKQINDKGAKLEEFREIRDG
                     NVFQRTLDAILEGGKLGVEMGMAIIPGVLVVCTLVMLLTFGPSTDPATGQAVYTGAAY
                     EGIKLLPAIGDKISFIIEPLFGFTSPEAIAFPVTALGAVGAAISLVPEFIKSGAITPN
                     DIAVFTAMGMCWSGYLSTHIGMMDALDARPLAGKAILSHTIGGLCAGICAHFIFMLVG
                     "
     gene            complement(16946..17440)
                     /locus_tag="OE968_002277"
     CDS             complement(16946..17440)
                     /locus_tag="OE968_002277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HCP7219554.1"
                     /translation="MHLFIEVIAAFFTALSFGVLFNMKGKNLILAGIGGSIAWFSYKF
                     LLNMGVTENLCFFIATVCFAIYCELCARIYMTPATTLSVCCLIILVPGYGIYNTMYSV
                     LTNNYIKAVEYGVSTLSCASSIALGLVFITTVFRKVNLYGVLTKIKENEKYKKSINKI
                     KQQK"
     gene            complement(17441..18202)
                     /locus_tag="OE968_002278"
     CDS             complement(17441..18202)
                     /locus_tag="OE968_002278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HCP7219555.1"
                     /translation="MDIDRILNFSSNAGKAMLQSGGETYRVEETIARICQSFGIDHVD
                     VFATPTAVMASVFVDGKLHSAIKRISSRRVDLNLVHEVNSLSRAISINNLDIELCEKI
                     LDEISEDNYYSDLITIFFAGIAAATFSILFGGNVEEFIAAFTVGILTKFVIMYLSKSS
                     LNDFFVNAIGAVIIASCSILILKLGFIKTLDHLIAGAIMLLVPGLALTNALRDLLDGQ
                     LISGLAKLAEVFFVGVSIAVGMFLVLGLYFKLGGI"
     gene            18924..21758
                     /locus_tag="OE968_002279"
     CDS             18924..21758
                     /locus_tag="OE968_002279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HCP7219556.1"
                     /translation="MLRKDKVLLSLHKLCENMTLKDLQSDKTGFTTIEIANHSSLDRS
                     NTSKELNNLYNEKKVLKISGKPILFLHASIIENLIGRTLNSDEFSINNCNELLKSSKN
                     DSEDIFSTLLGHDSSLKLPIEKAKSAILYPPKGLNTLLIGPTGVGKSTFAETMYKYAV
                     ESKIFSSESKFVVFNCAEYAENANLLLSNLFGYVKGSFTGANKDKFGIVAQADGGILF
                     LDEIHRLPPEGQEMLFLLMDKGIYRRLGESDIVHKANVFIVCATTEDIHSSLLGTFLR
                     RIPVTINLPALQDRSLKERLSLIKYFFIIESKYTNATIKVHKDVIKSLLLYDCFGNIG
                     QLKSDIQLMSARAFLNYKTGLKDNIEIDLSLVPDYIYIGLLKLNENRSNLNKLSELDY
                     MLFYEFNGNNLEVEYTKELSKYNIDTSNNGFKYSTEIPYLENDIRSMFINYMEKYSTK
                     LLSISSVTHSDYTSNEIFKVINPKIYYAVEHSLKEAEKISRNKYTKQTYIALSMHISA
                     LIENINQDTYNPKYNLYNDKIFLDKDLNIAKIVLSIIENDLQTSLPKDEVKFISMFLN
                     SMYLEPNNQSESIGVIILAHGNSTASSMCDVANSLLGTNHCNAIDMPLDVKVSTILDK
                     TIELVKECDEGKGVLLLTDMGSLIAFGELISEKTKIKTRSIEMVSTPIVLEAVRKSTL
                     PEMTLDELANSLSSLNPYIGRAAIDSTEINYPEKSREYVIITTCITGYGSAMKVADFI
                     NSSLKNISKYNINLVPHNIESFKMYKNKFSNTKILAVVGSVDFNVANTPFIHIEELLN
                     GYGLDMLNKIIEGTFNANSITNIKETNLSYNSLIINFMTQNLELLDSVKLFNYVNSSL
                     FTIIELIDENLKSKFKLGYILHCSFMIERCFKNTTFPYNNITELISKNHELYSLIREA
                     FKPTEAYFNILIPDEEIAYIIDMINEYLNK"
     gene            21801..23045
                     /locus_tag="OE968_002280"
     CDS             21801..23045
                     /locus_tag="OE968_002280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HCP7219557.1"
                     /translation="MEDEILKGKIKQLTILALIFIFITPVFAFADTPPVPNSSRAALL
                     IDQETKRILFEKNIDEKMPLASLSKMMTFLLAIEAVDKNQVKETDMVKIDKSTASVGG
                     STCKLKDGDEISLGELMQGLMLVSGNDAAIAIAKHIGKTEKNFVNMMNKKAEEIGMID
                     TYYFNPNGLPIYTDPEHKEPPIENMSTAHDIVTLGKYMYDHYENQVTRITTMQVYNDT
                     KKDFTHYNTNPLLVSVPGVDGIKTGYTDNAGYCLAFSMMVPKDAKNERNHRLIGVVLG
                     DGNKKNRISSSATLLKYGKDNFHSKKIAHKGDIIETPCVDGIDDFKITVKVDKDLYGV
                     VSDNENINPKVVFKNMNYPIHKGDIVGVVKYYNDSGKFVGSVDVKSESNIGCIPLKDK
                     IKIKVAKINKKLEIKNSVCFKA"
BASE COUNT         8326 a         3668 c         3101 g         8569 t
ORIGIN      
        1 aatttactat ttctcaattc tatattatta tttttcaatt ttatattact aattttaaag
       61 ctttttagct attattccta caatatttaa acaatttttt aataataaag ctatattaca
      121 atatattcaa aatatgtaat attttagata tttttcgttg acaatgttaa atttttgttt
      181 tatccttaat taaggacatg ttattgacat ttctgaaact tatttgaaat agttttttca
      241 ttttatttag gaaaacgtat tatacctaag aaaacgtatt ttctcatttc agataagtaa
      301 aatatttatt cttttgggga ggaaatcatg gaaattaata aaaaacattt tattcaagta
      361 tttttaactt gcttaatctt ggtagtaata tgtgaattta tagggcaaag aactatagct
      421 attggaaaag cctctatagt actgttccct atgctttatg cagttataat tggacttata
      481 ataacaccag atttattagg taaaaaaatt aaagcactta aaaaagtggt tggagaaaaa
      541 gaaataaata ttgctggtga agttgttgga attgcactag taatgcttgg tataaaatat
      601 ggtactacag ttggaccaaa cattgacaaa ataattcaag ctggaccagc atttatcgct
      661 caagaatttg gtcatatact tgcaccaatc gttgcattac ctcttgcatt aatgtttgga
      721 atgaaaagag aagctgttgg agctactgca agtataagtc gtgaaccttc tttaggagtt
      781 atatcagaaa aatatgggat aaactcacca gaaggtagtg gtgtacttgg tacatattta
      841 atgggaacag ttcttggtac tatatacttt agtgtactag gttcaatatc tatttatagt
      901 ggtcttcacc catatgcttt gggaatggcc tgtggtgttg gtagtggaag tatgatgaca
      961 gcagctgctg gttcattatc taccatggta ccacctgaaa tggcagatac aatacttgcc
     1021 tatgctgcaa caagcaatat gatgtctagt ataacaggaa ttatattctt agtttttgta
     1081 tccttaccat ttactaattt tatgtataag attttagaac ctaaattttc gagaaataaa
     1141 aaaactaaag aaattaaatc tacagaagga gagtgctaat aaatgtttgc taatttaaat
     1201 ttaaagaaaa gttcatatca attattggtt atgtctgtta ttggagttat aattcttata
     1261 ggacaaagaa ttagcgttgg tacatctata gttacagctc ttcctggtat ggtgatgcta
     1321 atattagctg ctatggcagc tatgattata aaagatttat ttcctaaatc aatctttcca
     1381 gcttttggat ttgcaactat aatcggcctt ttacttagta tgccatatag tccaacatct
     1441 gaagtattct taactaacac taataatatt aactttatgg ctataactac tccactacta
     1501 gcttttgcag gaatttctgt tggaaacaaa atagaagctt taaaagaaat gtcatggaaa
     1561 atagttataa tttcacttat tgtatttaca actatattct ttgcatgtgc gagtatagct
     1621 catatagttt taagtattca aggtaaaata taggaggaat ttattatgaa taaagaacaa
     1681 ttaaaatctc tagtaataaa aactatagat gaaaatagag aaaaaatatt aaaaataggt
     1741 caaggaatat acaaaaatcc agaatatgga tataaagaat ttaaaactac agaagctgtt
     1801 tcaaactttt ttgagcaaga attaaattta tctgtagaaa aaaatatagc agttacagga
     1861 tgcaaagcag atgcaaattc tagcaagaaa ggtcctcata tatctatact tggagaattg
     1921 gatggtatat catgtaaaga acataaagat gctaatgaaa taggtgcttc tcatacttgt
     1981 ggacataata ttcaaatagc tggaatgtta ggtgctgctg ttggtttagt aaaaagtggc
     2041 gttttagaac atttagatgg taaagtatct tttatggcta ctcctgctga agagtttatt
     2101 gagttggaat acagagagca attaaaaaaa gaaggaaaaa taacttattt tggtggaaaa
     2161 caagaattaa taaaaagagg ttattttgat gatatagaca tatctatgat gtttcatgct
     2221 tctgatttag gagaagataa ggctctagtt ggtcctgaga gtaatggatt tgttggaaaa
     2281 aaggttaaat ttataggtaa agaatctcat gctggttctg ctccacatga tggaataaat
     2341 gctttaaatg cagcaatgct tgctataaac aacgtgaatg cacttagaga aacttttaaa
     2401 gagtctgaaa gagttagatt ccaccctatc atcacaaaag gtggagatat agtaaatgtt
     2461 gttcctgctg atgttcatat ggaatcatat gttagagcta gaactataaa tggtatgatt
     2521 gatgctaatg aaagaataaa taaggctttg atggctggtg gaatggcagt tggagctgat
     2581 gttgagataa ctgaaattcc tggatatctt ccaatattac gatacaaaag tcttgataat
     2641 ttatttaaaa acaatcttga agatttaggt ctaaaaggaa aagttattga tggtggagat
     2701 tttacaggct cttttgattt tggagatgtg tctcatataa tgcctactct tcaccctatg
     2761 attggtggtg taaaaggagc tcttcataca agagattttg aaatagttga tgaagattta
     2821 gcttacataa ttcctgctaa agcaatggca cttacagttg tagaccttct ttttgataat
     2881 gctaaggatg ctaaagatat attagatacc tttactccag ttatgactaa agaagaatat
     2941 ctaacattct tagaaaaaca cgataaaact ttataagtct atttttataa tagggtggta
     3001 tctactgtaa aagttatacc actctttgtt tttgtaacag tatacttctt ttcttttagt
     3061 ttttagatta aactaagata tattatcctc cttaaaactt ttagagctac gttgaaatat
     3121 cagtagaact atgctatatt ctttctaatt aatataaatt tctattctaa ttcaaggtgg
     3181 tgaaaaaatg tttaatgcag gaaatcgaat tataaataca tggttgtacc ctattcaaga
     3241 tggctttgtc ttgattgata ctggatatga aaatggtttt aaacatttca aaaaacgaat
     3301 ttctaaattc aacataaaaa tcaaagatat tcgatacata tttctaactc atgctcatga
     3361 tgaccatgtt ggttttctaa atcagattct agacgaatct cctaatacaa agattgttat
     3421 gcatgataaa gctttagaaa ttctatataa aggtcaaaac tcttttattg gtggttgtac
     3481 cagccgtact gcctttctct tttgccaaat tatgaaacta tttggaaaag gtgagcatag
     3541 tttttctcca cttaaacaag aatttgaaaa aaggtgtatt cttgtgtctg acaagaatcg
     3601 taaagaaatt gaaaaagaac taaatggaaa aattatagat acaccaggac atactgctga
     3661 ttcaatttca ctactaattg atgaaggtgt tttattttgt ggagattctg caatgaatgg
     3721 atttccaagt actcacaaaa ttaccatatt tgcagaaagc aaactagaat ttattcaatc
     3781 ttggaaaaca atcatcaata caaaacctaa aatgatttat cctggacatg gaaaaccatt
     3841 tgaatacagt aaattagaac aaaatctaat ctatgtaaat aaaataaatt tatatcctct
     3901 acataattca aaagatattc acaggttttt gtagaaaata caaagtaaat ttatttgatt
     3961 aattaaaaaa tctaacactt tactacgcta cttattttaa taacttaatc ttccactagc
     4021 ttttcataaa attttgtttt aaaattaatt ttaaagcgca tatgttattt aaatacatta
     4081 gataaaattc gtcattaatc tacttaaagc atatttaact aacaccactc aaccagaaaa
     4141 ttcagaaaac tgcattgaca caggaaaaag tttattttat acttttttta ggacatattg
     4201 tggacacgtc ttaaatcgac aaacagaatt taaattgtaa gattaaccac aatacttatt
     4261 ttttaattat atttttaaac attagggagg atattatgaa tgataacgta gttaagaaga
     4321 aaaacttttt tgacaggaca ttaaacagaa tagaaactgt tggtaataaa ctaccagacc
     4381 cagttacaat atttttaggg ttatgtgtac ttttacttat actatctagt ctagttggtt
     4441 ctatgggtat atcagtagtt catcctggta ctggagaaac tataaccgct gtaaatttat
     4501 tgactgtaga acagcttcaa attcttttag gaaacatagt cagcaatttc caagggtttg
     4561 ctcctttggg tctagttcta gtaactatga taggtgctgg tgtatgtgac aaaacaggac
     4621 ttatgacagc aacaatcaaa gcatcagtaa gcaagattcc tgaaacaaga gtaactcttg
     4681 ttgtaatgac tataggtatg cttgccaata tagcttcaga tgcaggtaca atattatttc
     4741 caccattagc tgcacttgta tatcttggtg ttggtagaca tccacttata ggtttatttt
     4801 ctggatatgc agcagtctgt ctaggatttg ccgcaaacat tatgataagt gtcaatgata
     4861 tacttgctgc aagttttaca gttccagcag ctcaaatgat tgattctgga tttcaagcca
     4921 atgcaacaat gaacttattt tttatgatag catcaacttt tgttctaata cttttggcaa
     4981 catgggtaac agaaaaaatt gtagctccta gatttggtaa atatgaagga aatgcagaac
     5041 tagatgttga tggaagtctt agtgatgtag aaaagaaagg gcttaaaaaa gctggtataa
     5101 gtatattaat atatgtggct attatagtag ctcttagtgt aatcggtaaa aaaccattct
     5161 tagctgaccc agaaacagga gatttactat caaacaatgc tcctcttatg aaaggtatgg
     5221 tacctataat agcactagca tttttcatac ctggtgttgt atacggaaaa actataggta
     5281 aaataaagaa ggataaggat gtagtctcta taatggctag tgcaatgagt gatatgggtg
     5341 gatatataat actagcattt gctgcttcac aatttttgca attattcaca aatagtaatt
     5401 taggtctgat actagctgta aagggcggag aatttttaaa atcagcagga ataaatggac
     5461 ctttattgtt gataggattt attatattat catgttttat aaatttattt ataggtagtg
     5521 catctgcaaa gtgggctatt cttgcaccta tatttgtacc aatgtttatg atggttggat
     5581 acaatccagc acttactcag atggcttatc gtataggtga ttgtataaca aatccactta
     5641 gcccattatt tccgtacttc cctattatac tagcattcac aagaaaatac gataaagatg
     5701 ctggtatggg tactgtaatt gctaatatga taccatactc tatatcattc ttaatagtgt
     5761 ggactatact attaatattg tttatggtat ttaatattcc actaggacct ggaatacttc
     5821 cttcatatag catgtaattt atttaaatct ttctaaaagg agaaataatt tatgttagat
     5881 aaaaatagac ttataaataa ttttatggat atggttagaa ttgatagccc atctaatcaa
     5941 gaattagaaa tgtctaagtg gttggtaaac tacttaaaag aaagaaatat agacgccatt
     6001 atagatgatg caggtgaaaa atatggtggt aatacaggta atgtcattgc ctatataaaa
     6061 ggtgaagaag gaagtagacc actttgttta tgtgcacaca tggaccaagt tcaaccttgt
     6121 ttaggtgtaa aaccaatact agatggtaat gtagttagaa gtgatggaac tactacactt
     6181 ggtgcagatg ataaagctgg aatagctgct atacttgaag ctttagaaca tgttattaca
     6241 gaaaaaatac cacatagaga tatttatctt tgttttacaa tctgtgagga agccggtatg
     6301 catggtgtca aaaactttaa tcctgacaac ttgccttgta aagacatggt gattttagat
     6361 tctggtggag ctattggttc gatagcatac aaagctcctg ctcaacaatc tataaaaatc
     6421 tcttttcatg gaaagaaagc acatgctggt atagaacctg aaaaagggtt aaatgctata
     6481 ttagtagcct ctcatgcaat aagcaacatg cacataggca gaatagattc attgactact
     6541 tcaaatatag gtaaaataga aggtggtgga gctacaaaca tagtaactga taaggttaca
     6601 ttgactgctg aaattaggtc tcatatacct gaaactttag agtatgagct taatcatatg
     6661 gaaaaatgtt gtaaggatgc tgcatctaaa tttaatacta cttatacttt tgaacatagt
     6721 atgtcttacc ctagttttga acttagtaga gatagtcatg ttttcaagtt aagtgaagaa
     6781 gcaataagac aagttggtgt tgttccaaat ccaatggtaa ttggtggtgg aagtgacgca
     6841 aatatattag ctaatcttgg atataattgt gctatattaa gtctaggtat gtatgatgta
     6901 cacacagtta atgaatatgt aaatatagac gaattatatg atactgccaa aatagtttat
     6961 catatgatta aattataaat atcataatat aactctttaa attataaaaa taaaaaccta
     7021 tgtatcttca actttataag ttatatatta aagttgtttt acataggttt tagtatttta
     7081 tataataatt tgttttaaca tttttcataa taagcttcaa tattttgcat aataatttgt
     7141 tctagcattt ttaataacaa gctttagtat tttatattaa taatttattc tagtatttta
     7201 cataatcatt tgttctaatt tttttcataa taagctttaa tactttatat agtaatttgt
     7261 tgtagaattt tatacaatat aatgatttat acagttttat aaaatatctt aaaacagtat
     7321 ttcagtaata ttttttggtc ttcctccacc aatactagtc tcttttgcac atattcgacc
     7381 taaacctgca tttactattt tatttaatat acgtcttgca cttctttcac ttacatttag
     7441 atactctgct aactcttttg aatcataaat cttacttttt ctattctcat ttatagcaat
     7501 aatttttgca actgactcac aactcattcc agtcttttta gatatttcga ttaccttttc
     7561 atcagatagc atcaaagaat aatttaattc attttcggaa gctaaaggtc ctcttatgtt
     7621 ttcatcttca tctaccaaat atataccaat ttcttttgaa tctatggagt gtcttaatgc
     7681 tttatgtgca ttattttcag cctgatacgc agttactcca gtaccaattc ctatactaag
     7741 agaaaagccc atgtctttta tctctctctt tagattgaat agcttatcat aattatactc
     7801 attatcagct acccctttat gaacaaatac aacataatca tttcttccaa gtaaaaataa
     7861 ggaaccttga atacttctta catagtttac tacaagctta tccatatctg atttttttat
     7921 catgtcagaa taatagttat ctatcttctc tttataatct attaaactca atatttcaac
     7981 agcaatttga gaaaatcttg ccttacttag agcatattca ctctttacct tgtcataact
     8041 ttctttgatt aattgtatag tagcttgtaa acgaaataca ggatagcctc tttcttttaa
     8101 ttcattatat actgcaccaa aaccagttaa cattatatcc gtcttatttt cttcaaataa
     8161 ttttatatgc cattctacaa gttcagactc tcctacttcc aaagaaaatg gattacaaaa
     8221 tacactcgtt gctttaatat caaattcttt aagtgcatct tccacaacat atctatcaac
     8281 tacatctata ctgaatttat ctaattttat atttgcactt tttattgccc aaaatgcctt
     8341 cattatactc gtcccacttc tcggtacaaa tgaatgtggc ttacttatct catacttaga
     8401 ttttataaat tcataaactg cacatcctgt aaatataata gcatcacatt cgtcttcaca
     8461 tttagaaata acttctattg tatctactac tttttctctt acatatattt tagtctttaa
     8521 atcactgtct atctgtttta aatcatcctt tatcttaaac ccagagtctg aaggacctat
     8581 aatacccact atcataaact tcgctcctaa tccataaata ttatactttt taaaaattat
     8641 atcctcacta ttttctactt ctatttaatt attttgaact actccatcct acctacattt
     8701 agaatggaat aattagctta tttttgataa agtaacttct caaaatcaga acttggaata
     8761 ggcttacaat aataataacc ttgaattacc acacaatcta aactcactaa aaattcagct
     8821 tgttcttttg tctctacacc ttctgccact acatccatat ctaaatcttt tgccatggct
     8881 atagtgtgct ttaaaactat tttttctctg tctgtgattc cttcctcatt aaagaaacca
     8941 caatctatct ttaatgtatc aatattaata ttttttaaca tatttaatga agaatatgct
     9001 gaaccaaagt catccatatt taaaacaata ccatccattc taaggtcggc tattatctta
     9061 gtaaataatt ttatattttt aataaataaa ctttctgtaa gctctaattc taaaaaagat
     9121 tttggtatac tatatttatt tattaaactt aaaacaattt ctttaaaatg tggattatgc
     9181 aaatgtaatc ttgatacatt tacagagata ggaactggct cttcacctaa atctatccat
     9241 tttctaatca aagaacatac ttgttcccat acatacatat ctaatctgat aataaaccca
     9301 ttcttctcaa atagtgaaat aaatttaatt ggaggtatta tacctttttc tggatgaacc
     9361 catctaacca atgcttctgc accaacaatt ttatttgcat taagattata cttaggttgt
     9421 aaatatacat ggaattgccc attttcaagt gcgtattcca tttccctttc catctgtttt
     9481 tcttcaagtg catcatttct tatagtatca tcataaaata tatagttgtt gatactttgt
     9541 ttctttactt ttttgtgagc atatcctgcc atttcacacg catttgtaat tggaatatga
     9601 ttatccaaaa ttctataaac cccaaaacat ggtactaaca tatattcaaa tttttttcta
     9661 tttaagctat ttttaatctt ataaattact ttatgaatat ctctatcaga gtaactctca
     9721 taaaaaatgc aaaatacatc tgcatacata cgacaacata taccattaga accaatgttt
     9781 ttttgaatca actctgcaac atatattaaa gctttatctc ctcctctaac tccataaatg
     9841 tcattaatta ccttgaactt atctatatcc atcattataa ttgcataacg cttgtcagga
     9901 tatcttttaa gcattaaact tatttgttca caaaaacttt cataattgta tagtcctgtt
     9961 aatgtatctt tttggttttt atgtagttgc ataagataat ctatattttt tatagcaact
    10021 aaaatatgtg tttgtttctc acctaactta tttttactac taatctttaa catataaatt
    10081 aatgcccaat agtacttttt atctattcct aaacgtctat actcaaaatt tagttctaaa
    10141 tcgtcttgct tgctattatt aagactatca agagatttta gaaggtggtt atcattaaat
    10201 aatattatat catcaggatg aattaaatat ttttttatgt atgaaaaagt tttttcaaga
    10261 ttttccttta taggaaaact aaaaatattg ctctctgatt gataaattgg agtaattaaa
    10321 ttcgtatcaa tgcaaataga taaaattata tcatatgtat tataagctaa tttttcataa
    10381 gctttagaat acccttttat cattaaatca tcaaaataaa ccttatcaac taactcttta
    10441 tgtttaaata aaatattatt cgtcgaatca gctaagtcac taattacttt catttcatta
    10501 tttctaagtt tgttcttatt ataatacctc ttcttatctt ggtacattct ctcatcagca
    10561 actttaatta gcttatgtat atcaatatta tcgtcactcc aaatactgcc cactgctaca
    10621 ctatatatca tctcatcctt aaattcttca cttaaccaac tcactaattc ttcaaatagt
    10681 tgttttgata tatcttcaca taatacaaca aactcatctc ctccaatacg gtaaacatta
    10741 taagaatgaa agtatttttt tattattaca catgctgaca caatagcaga atcgccatta
    10801 gcatgtccaa agttatcatt aatatctttt aacccattta tatctacaaa tacaactcct
    10861 atggatttaa cttttccttt ttgaaaatta tctatatact taatatattt atttctatta
    10921 tatgcaccag tcaagaagtc atagtagctc atataattta atttattttc tacttttctt
    10981 tttttcatct cagttaataa aaaataagat agggatgtca aaagagaggt atctccaaca
    11041 gctttatgtg gattatcaac tccaataaac cctactactt tatcatcttg ttttagtgaa
    11101 gatgtcatta aactttcaat tttttgaggt tttaaaattt catattctat tggctgttct
    11161 tcttttatat tttctatatc atcaattatt acaaaacctt tttgttcgaa taataaaaac
    11221 caattcttta attcattaat atcaagattt gttagtgcct gtttttgttc atcaacacct
    11281 tcattgcacc attcatatgt attagttact tttgttctat cttctgatac ttcaaaaaca
    11341 tatgctctat cagctttatg aaatttacca atattggtta atacaagatt tacagcatca
    11401 gaaaaattag attctgttat aagatgttta atacatccaa ctaataactc ctttatctct
    11461 aatttttctg ctattgactt acttatatct tccttttctg taatatcaag agctatttct
    11521 aatcgtgcat gtttgccctc ccatttaatt aacttgtcct ttaatataaa atgtctattt
    11581 gttcgagtat tcgtattttc ccatatgtaa tattcatctt cttttaaaat agagtttgta
    11641 caaaattcgc agggagaatc tttcccctgt aatgctttat aacattttaa atgggatata
    11701 tcattaagtc ccattgcctt tttcccaatt tcattaatat ataaaagttc atatgtatct
    11761 aaagaagaaa catatacaat ttcatccaac tcatctatta aatttattac atccatttat
    11821 atatatctcc ttttattcat tttccagatt gaatttttaa agcttttaaa attttgctat
    11881 atatttggca atgatattat acttctttat gttttaaaat agtaccttaa tgaggttcta
    11941 ttttttagta aatagaatta ttattgtgtc aatcgtacaa tagagttttg taatacttaa
    12001 tttaatatat ttataattaa ctatcttatt atgtatttac aattaattct catataaatg
    12061 acaaatctcc acctcaatta agtattccaa tcatatatga ggataatact tcattcattt
    12121 aaaaatataa aactattata tattaaaatt tcttcaataa taaattattt agattgttac
    12181 tttgatatat tatataatat cacaaaggct gatataaaaa gacaaaaagg gcaatttttt
    12241 tatatcaaaa aaaatgttaa attgatatta tccatatata aattgatatt atccatatag
    12301 gtgctatatt taacaattct acttacttcc cttacactta ttagcatata gttattaaga
    12361 gtttgttgca aaacaacact tagcacactt taaaaagtgt ggtctaataa gtaatcaacg
    12421 aagaagacat aataaagcat aaaataggat atacttttcc acgtcatcaa aattgaggat
    12481 tttattatta atatatgata aaatatgctt aataaattaa attttaatgg gagaatagtt
    12541 atgaaaatat ttagtttctt gttgtttgta gtgggaatat gtttttgtat tgctggattt
    12601 atggggcatt cctcagcttt ttctggtgca acattgagtt tttttgcaac tacaatgata
    12661 gctgtaagac aagtcaaaac taagaaaaaa tgaaataggc aaatcctaac tttataagtt
    12721 aatattacat aagtaattag tctaaaatta gatacttttt ctattacaaa aatacatcat
    12781 ccactttgta ttctcttaaa aaaaataaaa tagctatgta aattcaagat tagatagact
    12841 aactctctat ccatttcatt gtaaaatata catagctatt tgtattcgat ttaaaatact
    12901 tagattttct tacataacaa ataatttcta tctgattatt actcatgttc atttattaac
    12961 cactcagcaa ctaatcattt agtatctatt catccgccat acggtaacct accccaacct
    13021 cagtcaaaat atattctggc tgagcaggat tcttttcaat tttccttctt atacttgcca
    13081 taaaaactct aagcgactga ttttcacttt catagtaatt tccccaaact ttatctatta
    13141 taaacttatg ggttaagact cttcctgaat acttagacat caactcaata atcttatatt
    13201 cgattggagt taaatgtatt tcttcaccat taattgacac aatatgattt tcataatcta
    13261 tctttaggtt tttaacttca aaagactttg gagcatcatt atttatatta tcctgttgag
    13321 ctttatttct aagagccaca cgtactctag ccaaaagctc tgttacacta aaaggtttag
    13381 ttaaataatc gtctgctcct ccatctaaag cttccacctt atctctctca tgctctctcg
    13441 ctgaaacaac aattatttta ttagtctttg cacatgccct aactcgtcct attacctcaa
    13501 tcccatcaat atctggtagt cctaaatcca aaattatcaa atctgggtca agagaatgta
    13561 taagtgatat agctgttcct ccattatctg tctctacaca cctataattt tgagtttcaa
    13621 gagatacttt tataaattta caaattggct tatcatcttc tacaattaga actaatggct
    13681 ttatttccac ttgtctttcc cctcctcatc atacataggt atgctaaatc taaatgtagc
    13741 tcctccagaa ggattattaa aggcgacaat ttctccacca tgagcttcta ctatagattt
    13801 acatatctcc aatccaagac caatacctct tctttcaaga tttctagact tattcttagt
    13861 ataaaaccta ttaaaaatat tcccgatatc ttcatttggt attccttttc cattatctgc
    13921 aacttcaaat agtacttgat ttgactcttt ttttacagtt agttctatct tagaattttt
    13981 aggtgtatgc cttatagcat tatcaattag atttactaac acttgttcta ttaataatac
    14041 atccacatga acgattatta tctcatctgg aatatttgtt tttatgtctc tactattggc
    14101 aaactttttg actcttaata tagattcagc tattatttca tcaacaacct ctggtcgttt
    14161 ttcaatatcc aattttcctt catctattct ggtcatacta agtatattct caacagaatg
    14221 agttagccaa ctcgtatctt catatatatt tttcaataat tctactctag tttctttatc
    14281 tatcacatca tcattttcaa gtattgttga agatgaaccc aatatacttg taagtggagt
    14341 tcttaaatca tgagaaattg acctaagcaa gtttcctctt aacctctctc tctctgcctc
    14401 aaggtttgct tttttatttt tctcaaataa attttctcta tcaattgcca acgcaacctg
    14461 tgttgaaact gcttctaata gtatcttttc attttctgta ataatatcta tcttaaaaca
    14521 cgcaacacct ataacaccaa gaacatttga ttcttgacct tttataggga aataatatgc
    14581 actgctgttt ttacaatatt ttgtcccaat tccaactggg ttacctgtcc taaaagcttc
    14641 ttttatagct tccttttcta atactgaatg gaatatattc tcacttccat cattgttaca
    14701 aatataaata cttggcttac ctagattatt attctcatct gcaatagtca ctattacagt
    14761 tctatttaat atatttacta aattagaccc acaaaattca ataatttgat ttttattttt
    14821 tgctttaagc aacgttttgt tattctcata gagcaatctt atcatttttt ctctcttatg
    14881 agaaagtctc acttctcttt ttatcctaga agttaaagta cttgttataa ttgctgccat
    14941 tagcataata caaaaggtca taggataatc ttttctataa gctaaaaaag tatataatgg
    15001 atgcgtaaag aaaaaattaa atgatagcac tcctattact gaagaaagta ttccaaaaaa
    15061 atatccatag gttatacttg tagcaaatag tacacctaat atgtatacta gtataatatt
    15121 agattcatta aaacctacct tttcaaaaac tactgatatt ccagtagcaa ttgtcataac
    15181 caatatagtt tttatgaagt ccttaataat tatcttttta ctgagatagc catcttcatc
    15241 ataatcatac tcttttaagt cttcatgttg tagtcgttcc tttttcattt actacaattc
    15301 ctccttattg ttactgttta aattggctct attttatata atacaatttt atcataataa
    15361 attcaatcaa tacatttaat taatgtactt aaattactaa aaggtgctgt cttaaaatga
    15421 aaataaatct ctatttcaaa acagcaccta tatatttaaa ttactaattt agtttttaca
    15481 tacttaaatc aatagtttta ttcaatttca taaattataa tacttcaatt ataaaacatt
    15541 tctatccaac aagcataaat ataaagtggg cacatatacc tgcacataaa ccacctatag
    15601 tatgcgaaag tatcgcttta ccagccaatg gtcttgcatc taaagcatcc atcataccta
    15661 tgtgtgtact taaatatcca ctccaacaca tacccattgc tgtgaatact gctatatcat
    15721 taggagttat agcgcctgat tttataaact ctggtactaa agatattgct gctccaacag
    15781 ctcctaatgc agttacaggg aatgctattg cctctggtga tgtgaatcca aataatggtt
    15841 ctattatgaa gctaatctta tcaccaatag caggtaataa ttttatacct tcatatgcag
    15901 ctcctgtgta aacagcttga cctgtagcag ggtctgtaga tggtccaaaa gttaataaca
    15961 taactaatgt acaaactact aaaactcctg gtattatagc catacccatt tcaacaccta
    16021 acttaccacc ttcaagtata gcatccaatg ttctttggaa tacattacca tcccttattt
    16081 ctctaaactc ttcaagtttt gcacctttat catttatttg cttttcagta tcatttttag
    16141 ggtcataatt ataatacttt ttagtaaaag tcaacataat tctaacacta ataatactac
    16201 ctattattgc cccaacatta cctattatag ctggtagtac atattcttta ccttgagcta
    16261 tcataaaagt tgttacaata agtcccatac caaaggctgt tcctaaatta cataaagcag
    16321 gtacttgata cttcttaaaa tattgtgtaa atgttttgtc tttagcaaat ggtataatag
    16381 ctggattatc agataaatat gttgcaacta ctcctgctat actagcacca ggtaagcccc
    16441 atataggtct cataagaccc ttaaatatct tattaactaa agatattact ccaaactctg
    16501 aaagcaatgc actaagtgca cctgcaagaa ctgccatagc cattattaaa aatactgtgt
    16561 ctaataaaag cgcatgtgct gtactcatta ttactttaaa catcattcct gcacccatga
    16621 tgcttcctac atatccaaat cctaccgcca atagtacaat aaatacgaag gtttccatac
    16681 ttactgcctt gactcttctc ttatccgaca gcttttccat cttgaaatct tccccctttt
    16741 aattttaaat taaggttcct aacattggta caaatttttt ggtacaaact gagttctaaa
    16801 acttacactc gtaatgcaag ttgtcagttt tttgaaataa aaaaaaatta cgtttataga
    16861 ataagaatat cctctttaat ttggatactc ttattctatt ttatgttatt atattatcat
    16921 ccttttgttt aaaagtcaat tttttctatt tttgttgttt aattttattt atactctttt
    16981 tatatttttc attttctttt atctttgtaa gtactccata taagttgact tttctaaata
    17041 cagtagttat aaataccaat cctaatgcaa ttgaacttgc acacgataat gtactcaccc
    17101 catattctac agcttttata taattattgg tcaaaacaga atacatagta ttatatattc
    17161 cataacctgg cactaatatt attaaacagc aaacacttaa tgtagttgct ggagtcatat
    17221 aaattcttgc acataactca caatatatcg caaaacaaac tgtagctata aaaaaacata
    17281 agttttctgt tactcccata tttaaaagaa atttatacga aaaccaagct atacttccac
    17341 cgattcctgc tagtattaag ttttttcctt tcatattaaa tagcactcca aagcttaagg
    17401 cagtaaaaaa agctgctatt acttctataa acaaatgcac ttatatcccc cctaacttga
    17461 agtacaatcc aagtaccaag aacattccta ctgctataga tacacctaca aaaaatactt
    17521 ctgctaattt tgcaagacca gaaatcaact gtccatctaa caaatctctt aatgcattag
    17581 tcaaagcaag cccgggaact aagagcatta ttgctcctgc tattaaatgg tctaacgtct
    17641 ttatgaatcc gagctttaaa attaaaattg aacaagaagc tataataact gctccaattg
    17701 catttacaaa aaagtcatta agggaagatt tacttaaata cataataaca aacttagtca
    17761 gaatcccaac agtaaatgca gctataaatt cttccacatt tcctccaaat aatatcgaaa
    17821 aagttgctgc tgcaatacct gcaaaaaata ttgttattaa atccgagtaa tagttatctt
    17881 cacttatttc atctaaaatt ttctcacata attcaatatc taaattattt atacttattg
    17941 ctcttgataa tgagttaact tcatgaacca agtttaggtc tactcttctt gagcttattc
    18001 ttttaattgc tgaatgtaat ttcccatcta caaatacaga tgccattaca gctgttggag
    18061 ttgcaaatac atctacgtgg tctattccaa aagattgaca tattctagct atcgtttctt
    18121 caactctata ggtttctcct ccactttgca acatagcttt acctgcattt gaggaaaagt
    18181 ttaaaattct atctatatcc acaaaacata tctcccattc ttttatagta ttattcatat
    18241 tttaatacaa gatattattt atttaaacta ttttaaataa ttcatatcca acatttacat
    18301 tttatgaaaa aacttgtttt ttatgcttgt caaaatcaaa ttttaagctt gtttacacca
    18361 taaaatggct gaattaatat ttgacaaaca ctttcaacca tttatataac cttctaaatt
    18421 gtataacttt ttactacaaa taaaattata tctcttttaa ttctttctct tgagtattta
    18481 gcttatagta acttcatatt tatatatgta caatataaaa cattattttt atgatacaaa
    18541 atataatttg taaatgtata tatgtattaa ctgtgtatat ataaattatt cttaacctta
    18601 tcagtttttt catatatctt catctatacc gaccatatat taattacatt gaccatatat
    18661 taataaatga tattacatag acttaagtat attaaaaaac ttaaatttag ttatttaaca
    18721 acataatact ctaatttaat ctataaaaat ccatacctaa tataatgcaa ctcttatttt
    18781 aacaccatct attacacaaa acaacatatt aaaaagtaaa atacaaaata tctactataa
    18841 accttatttt aatactgaat atatattata atatatttaa tgtagcttaa atatagttta
    18901 aacataaaga aaggaaacgg tatatgctaa gaaaagataa agttctatta tctctacata
    18961 aattatgtga aaatatgact ttaaaagacc ttcaatcaga taaaacagga ttcactacaa
    19021 tagaaattgc taaccattca tctcttgata gaagtaatac cagtaaagaa ttaaataacc
    19081 tatacaatga aaaaaaagtt ctgaaaatat ctggtaagcc aattttattt ctacatgcta
    19141 gtattataga aaatttaatt ggccgtactt tgaacagtga tgaattttct ataaataatt
    19201 gtaatgagct acttaaatca agtaaaaatg actcagaaga tattttttca acattacttg
    19261 gacatgattc tagtcttaaa ctacctatag aaaaagctaa atctgctata ctctatcctc
    19321 caaaaggtct taatacatta ctaataggac ctactggtgt tggaaaaagt acatttgctg
    19381 aaacaatgta caaatatgct gtagaaagta aaatcttttc ttctgaaagc aaattcgtag
    19441 tatttaactg tgctgaatat gcagaaaatg ctaacttatt attaagtaat ttatttggtt
    19501 atgtcaaagg ttcttttact ggtgctaata aggataaatt cggcatagtt gcacaggctg
    19561 atggaggcat attattctta gatgaaatac acagattacc accagaaggt caagagatgc
    19621 tttttctttt gatggacaaa ggcatataca gacgattagg agaatctgac attgtgcata
    19681 aagctaatgt ctttattgtg tgtgccacaa cagaagatat acattcttct ctgcttggaa
    19741 cttttttaag aagaatccct gttacaatca acctacctgc tttacaggat aggtctttaa
    19801 aagaaagatt atctcttatt aaatacttct ttattataga atcaaaatac accaatgcaa
    19861 ctataaaagt tcacaaagat gtaattaaat cattactcct ttatgattgt tttggtaata
    19921 taggtcagct taaatctgac atacaactta tgagtgcaag agccttctta aattacaaaa
    19981 ctggacttaa ggataatata gaaatagatt tatcccttgt tcctgattac atctatattg
    20041 gtcttttaaa attgaatgaa aatcgtagta atctaaataa attatcagaa cttgattata
    20101 tgctttttta tgaatttaat ggtaataact tagaagttga atatacaaaa gaactatcta
    20161 aatacaatat agatacatca aacaatggat ttaaatactc tacagagatt ccttatctgg
    20221 aaaatgatat aaggagtatg tttataaatt acatggaaaa gtactctaca aaattacttt
    20281 cgatatcttc agtaactcat tctgattata caagtaatga gatttttaaa gtaatcaatc
    20341 caaagattta ctatgctgtt gaacattctt taaaagaggc tgaaaaaata tcgagaaaca
    20401 aatacacaaa acaaacttat attgctcttt caatgcatat aagtgcactt atagaaaata
    20461 taaatcaaga cacatataat cctaagtaca atttatataa tgataaaatt ttcttagata
    20521 aagatttaaa tatagctaaa atagttttaa gtataattga aaatgactta caaacatctt
    20581 tacctaaaga tgaagtaaaa tttatatcca tgtttctaaa tagcatgtat cttgaaccaa
    20641 acaatcaatc tgaaagtata ggagtcataa tacttgctca tggaaattca acagcaagca
    20701 gtatgtgtga tgtagcaaat tcattgcttg gtacaaacca ttgtaatgca attgacatgc
    20761 ctcttgatgt aaaagtaagt accatacttg ataaaactat agagttggta aaagaatgtg
    20821 acgaaggtaa gggtgtactt cttttaacag atatgggctc tcttatagct tttggagaac
    20881 ttatttcaga aaaaacaaaa atcaaaactc gctcaattga aatggtatct actccaatag
    20941 ttttagaagc agtaagaaaa agtacactac cagaaatgac tttggatgaa ttagctaatt
    21001 ccttaagctc tttaaatcca tatattggac gagcagcaat cgattcaaca gaaataaact
    21061 atcctgaaaa gtcaagagag tatgtaataa taactacttg tataacagga tatggttcag
    21121 ctatgaaagt agcagacttt ataaattctt cacttaaaaa tattagtaaa tacaatatta
    21181 atttagttcc tcataatata gaaagtttta aaatgtataa gaataaattt agtaatacta
    21241 aaattctggc agttgttgga agtgtagatt ttaatgtagc taacacccct tttatacaca
    21301 tagaggaact actaaatgga tatggcctag atatgctaaa caaaataata gaaggtacat
    21361 tcaatgccaa tagtattaca aatataaaag aaacaaatct atcatacaac agtttaataa
    21421 taaactttat gacccaaaac ttagagcttt tggactctgt taaattattc aactatgtca
    21481 attcttcctt atttacaata atagaattaa tagatgaaaa cttaaagagc aaatttaagc
    21541 taggatatat actacattgc tcttttatga tagaaagatg ttttaaaaat acaacttttc
    21601 catataataa cattactgaa ttaattagta aaaatcatga actatatagt ttaatacgtg
    21661 aagcctttaa gccaacagaa gcttatttta atattttgat accagacgaa gaaattgctt
    21721 atataataga catgattaat gagtatctaa ataaataaaa tttatagcac ttattttgtg
    21781 catattaatt aatatatgaa atggaggacg agattttgaa aggaaaaata aaacagttaa
    21841 caatacttgc attaattttt atatttataa ctcctgtatt tgcatttgca gatactccac
    21901 cagtaccaaa ttcttcaaga gcagcactac ttatagacca ggaaactaaa agaatattat
    21961 ttgaaaaaaa cattgatgaa aaaatgccat tagcgagttt aagtaaaatg atgacctttt
    22021 tattggcaat agaagcagtt gataaaaatc aagttaaaga gactgatatg gtgaaaatag
    22081 acaagtctac agcttcagta ggaggttcta cttgtaaact taaagatggt gatgaaatat
    22141 ctctaggtga gcttatgcag ggtctaatgc tagtatctgg aaatgatgct gctatagcca
    22201 tagctaaaca tattggtaaa actgaaaaga attttgtaaa tatgatgaac aagaaagcag
    22261 aagaaatagg aatgattgat acgtattatt ttaatccaaa tgggcttcct atatatactg
    22321 acccagaaca taaagaacct cctattgaaa atatgtcaac tgctcacgat atagttacac
    22381 ttggaaagta tatgtacgac cattatgaaa atcaagttac aagaataacc actatgcaag
    22441 tatataatga tactaaaaag gattttacac attataacac aaatcctctg cttgtttcag
    22501 tacctggtgt tgatggaata aagacaggat atacagataa tgctggatat tgccttgcat
    22561 tttctatgat ggtacctaaa gatgctaaaa acgaaagaaa tcatagattg ataggtgttg
    22621 tacttggtga tggtaacaag aaaaatagaa tttcttcttc cgctacttta ttgaaatatg
    22681 gtaaagataa tttccattct aaaaagatag cacataaggg tgatattata gagactcctt
    22741 gtgttgatgg tattgatgat tttaagataa cagttaaggt tgataaagat ttgtatggtg
    22801 ttgtttcaga taacgaaaat atcaatccta aggtagtgtt taaaaatatg aattatccta
    22861 tccataaggg agatattgtt ggtgttgtaa agtattataa tgactctggt aaatttgttg
    22921 gaagtgttga tgtaaaaagt gaaagtaata taggatgtat tcctttgaag gataagatta
    22981 agattaaggt tgctaagata aataaaaaac ttgagattaa aaattctgtt tgttttaaag
    23041 catagtaaag catattatta aaagggtatg ttaaatttat aaagactcca ctttgtggag
    23101 tctttttgtt ttttacaaaa aattaaaata gtggcaacaa ttgaggatgt gagggagagt
    23161 tgccactatt ttgtataggg tattatatta tgtttttaag ctagttttac tatcttctat
    23221 gtttatataa taactcttgt gtgtgaattt aattgataat taatatgaaa attatgtgaa
    23281 gttttaagtt agttgactta gactattgta aattttttca gaaaaattct gttcataagt
    23341 ctattagacc accgaattat ttacctataa tattccgatc aaaaaatcta ttctttttta
    23401 aaagtaaggt catgattatt gtacatatat aaaaattccg aaaattaatc tacacactag
    23461 taacattaag tataataaat ttattttagt aaaactatta aaataacctc ataagaaact
    23521 atagattaaa tcaatcaatc taatctacag tttcttgatt attccttaat atttataatt
    23581 tacattattt gtttatttta aaactatctg ttacaaatct agtcaatgtt gaaaataaat
    23641 tcgctctgaa tatagtagat gatg
//
LOCUS       DAJMZY010000061        23074 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.061, whole genome shotgun sequence.
ACCESSION   DAJMZY010000061 DAJMZY010000000
VERSION     DAJMZY010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 23074)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23074)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23074
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.061"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            239..1075
                     /locus_tag="OE968_002281"
     CDS             239..1075
                     /locus_tag="OE968_002281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HCP7219558.1"
                     /translation="MNIKKIFNNNVVVSSLEDGTEIIVTGAGVGFKKKVGDLIDENLI
                     SKKYFVQDDQRDKYNQILNKTSIEYFKISEEIIEKANEVLNTQVNDSIILALTSHIEF
                     AVQREKQGIKLPNLILNETKQLYREEFEFGLWAIDEIEKRIGIKLPEDEAGYIAIHII
                     NGLENSQKDEGINILEFSKQVIQIIEEVHGFKLDVNSLNYTRLITHLKFFVQRILRKE
                     TYNDSDIEDMYKLVNKNYNKPKVCTEEIAALVLDRFEYKISKEEELYLMIHINKITNS
                     GC"
     gene            1428..3005
                     /locus_tag="OE968_002282"
     CDS             1428..3005
                     /locus_tag="OE968_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HCP7219559.1"
                     /translation="MKKNKLGLWNFFQMLGKTFMFPIALLSVSGMMLGLGAGFTDPKM
                     IEMVPFLGNEYVNLVLNFMLTIGLFAFNNLGALFAMAIPLGLLKKEKEFGAFSGLVGF
                     IAMHIGTNFYLTRADLLVPAEQMSTNGQAMIMGIQTYNTSVLGGIVAGLIVYAIYDKV
                     SNLKIPESLGFYSGPRLVPIVSLIVMSIVGLLIPIVWPPFFNAFQSLGRWISSAGPLG
                     YFSYAVAERVTIPFGLNHLVTSVFRFTPIGGTAVIDGETYFGTLNMFMAYVENNQIIP
                     LDLAGKMEQGKLMIQYGLAGAALAIYRTAKPENRKALKGLLISGVLTVIIGGISEPIE
                     FLFLFISPALFAFHTFMNGIANMVLPYLGVLMGFTGDLIAFISFGVLRGTATGWPIAV
                     LVAVLYFAIYYFVFKWAIIKFNIKTPGREDKEIKVSEGNGSDFKNLSTYKGQQMISAL
                     GGQSNILSLDNCVTRLRLKLQDVSLINEDAIKEAGGIAVVKLDEHTIQVIIGTQVYSL
                     RKQMDKAMEGHLEACND"
     gene            2998..4182
                     /locus_tag="OE968_002283"
     CDS             2998..4182
                     /locus_tag="OE968_002283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PatB family C-S lyase"
                     /protein_id="HCP7219560.1"
                     /translation="MINFDKKVDRLGTYCTQWDYVEDRFGKKDLLPFTISDMDLEFPF
                     EITEVLQERLNHRVLGYSRWKHDDFRNSVTNWYIKRFNCSVDSNWIYYSPSVMYSISK
                     LIEMLSNEGDGILINTPAYNAFYDVIINNNRNIIKSHLVNRNGFYSIDFNDFEKKCKK
                     SKIFILCNPHNPTGRVWSELELVKMIGICKNNDVKIISDDIHMDIVYDNRMTPILNVA
                     KDYLDSVFICTSASKSFNIPALTGSYVIIPNEGIRNKFENITRYRDFVNSPAILAILA
                     TMVCYDDCEYWLDELLKYLKENLKYTIDYIKDNLEPLKLVMPEGCYFAWIDFSELKIS
                     GEKFQKLLMDIGEVAIMSGSVYGEEGEFYLRLNVACSREKLEDGLNRIKKTMDYIAKR
                     IL"
     gene            4200..4799
                     /locus_tag="OE968_002284"
     CDS             4200..4799
                     /locus_tag="OE968_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HCP7219561.1"
                     /translation="MGYLKTMVDVMTTEMNAIRCLIDEAGIEYESIVSEIANCEGKVI
                     FMGVGKSAHIGKKLAATFASTGTPSFFVHATEAVHGDLGMIESKDITILISNSGNSME
                     VVNCIKYIKAIGSKTIAFTSNRNSVLAKECDYALIYPAKDEADHLNLAPTTSSTITLV
                     LGDSIACALSKSSNFGSSDFYKYHPGGSLGEKLKTANNG"
     gene            4823..5293
                     /locus_tag="OE968_002285"
     CDS             4823..5293
                     /locus_tag="OE968_002285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HCP7219562.1"
                     /translation="MFKMFKKKSIKSPISGKVIELSKIQDGVFSQKIMGEGVAIDSTG
                     DIVYAPINGKIVVVAETKHAFVIELENGMELLIHVGLDTVNLKGEGFEVLVSMGEQVK
                     EGTPMLKINRPLIESKGISLITPVTITNHSEYNMNTCNVGNSVEGGKDTVIEFK"
     gene            5665..6411
                     /locus_tag="OE968_002286"
     CDS             5665..6411
                     /locus_tag="OE968_002286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HCP7219563.1"
                     /translation="MKIENLSIDDIKRGYIFNDDLNCYSCIKCTKTYEVGEIYKIGNR
                     FFEASKAIELHMELEHSDYLEQLLNSDSKYNTLTENQKQLFQLFISDLPDKEIAKQVG
                     VSTSTIRHQKFIFREKAKQAKLYLALYESVFEDKSNKSSTIIPIHEHARMVDERYVVT
                     EEERKHILDTSFESMNPLKLKVFSSKEKKKVVILSKILEQFERGKKYSEKEVNQILES
                     IYDDFATIRRYLIEYGFMSRNKECTKYWLT"
     gene            6472..7146
                     /locus_tag="OE968_002287"
     CDS             6472..7146
                     /locus_tag="OE968_002287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase"
                     /protein_id="HCP7219564.1"
                     /translation="MNDELKSILYNKGVDIVRFVDISEFPINQTQGFSKAILFCIGLS
                     KKFITDIYNNLPTDSDEFLEKEEKVEELADWISKYIQNKGYRAYSQSEKNNLEHGYFE
                     KAYINPEMQSGISPLPHKTIANISGIGFMGKNNLFVTEEYGCAFSMCTVLTDAPISVE
                     RYPLIDSKCMDCNVCVENCPAKAIHGNEWTLPGKRESIIDVSKCFCVLRCMMSCPWSL
                     RYANQK"
     gene            7515..8861
                     /locus_tag="OE968_002288"
     CDS             7515..8861
                     /locus_tag="OE968_002288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 55 protein"
                     /protein_id="HCP7219565.1"
                     /translation="MEIETKTPDWINVLELNSKIDITGKYDVSNMIQNIVSDKSLEGS
                     IIYFPKGNYLFEKGIKISQQITLQGDSYYGGGNQVSNLDKKQSIIGTTNFITRGVSNM
                     SIITLSGTSQCIKNINFYYDSHDIEKIPPKNVSAITEYGETQGLSHFEHLFISGFSGI
                     GIEIPYYSTGNDITVSSCGLGMRLGEKSMLSSSKIYECKNGMEITTGVSLNNVRIEEI
                     KEIGINNKGFGFNLIMNLMVDQCGYCGFMFEKMCYSQITARITRCGQYYKSVDYNAYE
                     NMEDRKEEAYSIFYGDILENCNIVLMNSNIDTLENDSLDEHKIYVIKANETNNVMLTC
                     YAEADNFIQCAKGNLLLENGENTYKFYNGEICSVGGVQISDIDEKDLIKIIENTLYID
                     DKGKYLMVPRLKKNTVIYSVLDSTEEINKLHGGIWEQIDVKVLAGESMYYYKKIKD"
     gene            8888..10288
                     /locus_tag="OE968_002289"
     CDS             8888..10288
                     /locus_tag="OE968_002289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219566.1"
                     /translation="MEESIIIKDISGWINVLDYGICNDETKDVSFKLQEIMDAVPEDS
                     IIYFPKGKYLFESGVKIKKRLTLCGDSYILANVPKNTAGVTQFTFKGKKNPKSENIAI
                     ITAKSVRHCIKSICFYSDSCDRDMTSNHEPPTDGKPRFHHNVIINYRNISAIVCEDKQ
                     GESGHYKNLSFSGFSGIALDMPNNSTANDITIFTSGLGISTGENSTIANSKVWGCVDG
                     MIISTGTFINGMRVEEIKKVGIKNIGRGLNFITNITIDQCGYCGVWFDSISNVQISGN
                     ITRCGQYYYDVSYDNYLMLDNRVKEAYSLFYGNLLESSNIVLSNTNKDNWEDFKEDKH
                     KVYLVEALETKNVLLTCNIDATDWIVKSEKGNLTYNNMRQTVIFYDGKLSSINGIGIS
                     DEDYGDKVKIKKGNIYINSKDKDIKMHKPEVGDIMSTIIKDKSILSAHYGGTWEKIGE
                     KIEFGITVHYYKLIEK"
     gene            10498..11934
                     /locus_tag="OE968_002290"
     CDS             10498..11934
                     /locus_tag="OE968_002290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 55 protein"
                     /protein_id="HCP7219567.1"
                     /translation="MEGRTGIKDGRWINVVERGIKNDGSYNVGPALQDIIDEIETDFC
                     VLYFPKGKYLFTSGVKINKEIVLQGDSNSSTGTTQFITRGVENMSIITLTGKKQCIKN
                     INFYSDSCEIQVNKEPPTKGNPKYHYEMIINKNEKNVEMNNVSAILYDNSKNMIKGLG
                     HYENIYISGFSGTGIRIPYYSIVNDITVSSCGLGIDTGIDTIISNSRISKCQNGMRIR
                     TGTSINNVRIEKIQKVGLISSQVKGYEGYGSYKINNITIDQCGYCGFSFDSMKDSYFS
                     GIIRRCGQYYYNTDYDTYLSIKDRVEEAYSLFYGNYFTECNIDLVSDNKDNWDDGLEY
                     KHKVYVFKTLQIPKLTLRCNIDAYDYIVKSVHGGGNLMLKNNFNNYIFIDSSNPEVIN
                     GINFNYQKNGNLLRLNNGKLSYKNGKEETAIFRPNYGLIVASTDSECEQIETSYGGKW
                     EKLGSEVIGEETVYYYKHHEPDKTNQIQ"
     gene            12278..13222
                     /locus_tag="OE968_002291"
     CDS             12278..13222
                     /locus_tag="OE968_002291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1848 domain-containing protein"
                     /protein_id="HCP7219568.1"
                     /translation="MIVSVSRRTDIPAFYSKWFFNRLKEGFVYVINPMNPKQVSKIEL
                     NPHTVDCFVFWTKDVTPMLYDLNKLKDYKYYFHYTITSYGKEVETCILDKRKVIDSFK
                     ELSRKIGKERVILRYDPIFLSEKYTVDYHIKAFASLCNQLDGFTEKCIISFIDLYKKT
                     KFNTKALHIKPIEITEIETLSKEISKIAHKHGITLEMCSEEYNLSKFGIGKSKCIDDR
                     LISKIIGCEVEVKKDSTQRDICGCVKSVDIGQYNTCRHYCLYCYANFNYAKVEENCRL
                     YKEDNKLLIDTLRDDAKISIRDMKTIKVDKNKQISIFD"
     gene            13391..14323
                     /locus_tag="OE968_002292"
     CDS             13391..14323
                     /locus_tag="OE968_002292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HCP7219569.1"
                     /translation="MNLLKKYPIPIASLILSIFTLGNLLQSYSESLRNVIGFIGFILY
                     AIYIVKIILLRKGVKEQLENTLISSTFPTITMATMIFATYIKPLSLELSIMIWSIGIV
                     GHLVLIVLFSKKFLVKFSIKTVFPSWYIVYVGIVAASVTAPAFNQLLIGKIAFWIGFV
                     SYIVLIPVILKRVWIIKEMPEPSLPSIAILAAPGSLLLSGYINSFSDKNNVVLYLLFI
                     LSIVFYIIVLGYLPKLLRLPFYPSFAAFTFPMAISAMGMKLMNGYLTKSGHFISWISY
                     ASKLEEIIATVIILYVLVLFIIYLSKSETTSKAK"
     gene            14428..14895
                     /locus_tag="OE968_002293"
     CDS             14428..14895
                     /locus_tag="OE968_002293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C_GCAxxG_C_C family protein"
                     /protein_id="HCP7219570.1"
                     /translation="MKTKEEYLKEVRNISEEYFRKGEFFCSEAVLQTINDALGQPLSP
                     EITKLASGFPIGLGKAQCLCGAISGGEMALGIVYGRVHGEAMNPKMFEHAKGLHDYIK
                     KEYGATCCRAITKKWDGDNFMSPERKEHCIKITGQVTEWVADKLIEDEKLNIK"
     gene            complement(15139..15993)
                     /locus_tag="OE968_002294"
     CDS             complement(15139..15993)
                     /locus_tag="OE968_002294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009912760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake protein"
                     /protein_id="HCP7219571.1"
                     /translation="MLTIIIALLPVMGWGLMPIVANLKKSSPHEQLLGTSISAFIFST
                     IITLVIHPEITFFSFCISMISGIFWSLGQLMQFKAIQIASVSKVMPISNGSQLTFTTL
                     LAVILFNEWTSSKMLLIGSLSILCIILGILLTNYQTKKSTDKNMLKCVGVVLLSSLFL
                     SLYVVTNQIFLIEGYRIILPQSVGMLITSSIIVKYFSKEIVYRENVLFNLITGILWSI
                     ANLGMFITTNTLGVTISFSISQSCVIVATLGGIIFFKEKKNKKEWLAIFIGIILIMSG
                     VFMLSIIK"
     gene            16159..18123
                     /locus_tag="OE968_002295"
     CDS             16159..18123
                     /locus_tag="OE968_002295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HCP7219572.1"
                     /translation="MLTDMIQNREIKIIKFLLKEGHTTVKAIADDLDVSEKTVSKSLK
                     EVEAVLKKIGLSLIRKPKIGVYIDGDLKKILPYLDNKGSQIPTTREERVIYIYSVLLK
                     SNDYITIQQLSDELYISRGTIERDLAEVEKLLKNEGISIYKKPSKGIKLNISERDKRQ
                     LTAKFIHKFWSRNWYIKQEQESFYQAFEKIQADVNGIFSEDDLSIIIDILRNFSRERK
                     FEFSDYEFQSLVIHLAIAVERIRKGEYIEESLYTGNIENNQMSNTNYLAKQLEEKFSI
                     LLPKSEIGYINLHLVASDQHRDTNELKNTSTNPCETSTNNISNLREIIKNTLYETAYD
                     KDLIDGLTSHVHSSINRLKYGLSIKNPYVNTIKQNFSLSFEQALDLKKVIEFIYDIRI
                     NDDECAYIALHFEAFRERMKELPQNIRVILVCSTGLGSSRLLSARIKKYFPMIKIEKV
                     LSVQELVSSKIDADLVISTIYLELETIPTIVVSPILNESDIRTLERNIQNVSSCTSKK
                     YKSFRNLIFEENILLNIEASNYEDAIKYITDNLIKKGFAKEGIAKSAIERENLSYTSF
                     QSIATPHANPSYIKKSNISVATLKNPITWGNEKVEVIFFISLENDKNLELDEIYEVFY
                     DFIDNKKNINDILSATSTKEVYDLLVEESI"
     gene            18123..18584
                     /locus_tag="OE968_002296"
     CDS             18123..18584
                     /locus_tag="OE968_002296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HCP7219573.1"
                     /translation="MKISDVLKKEQIVFNLDTNTKEETIKKLSSIFVENGIVDNEEEY
                     VKSVLEREEHSTTGIGNGIAIPHGKSNAVKKSSIIFAKTKHKIEWDALDEKPVDSIFL
                     LAISNIDKDSNHLVLLSKLATKLMDDDNVDALKLANSEQEIINIFSEEGEM"
     gene            18587..18907
                     /locus_tag="OE968_002297"
     CDS             18587..18907
                     /locus_tag="OE968_002297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HCP7219574.1"
                     /translation="MKRKIIAVTACATGVAHTYMAAQALKKASKKMGHLIKVETQGAT
                     GIDNELTTKDAQIAEVVIFAVDTKVRNAERFEGKEILEVPVNAPIKDAEKVINDALKL
                     IDTK"
     gene            18923..20023
                     /locus_tag="OE968_002298"
     CDS             18923..20023
                     /locus_tag="OE968_002298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HCP7219575.1"
                     /translation="MLKKIVSELKKHVLTGISYMIPLVIAGAMIMAISRVGGSFYNIP
                     DIWDAKYAESASSIVRLLHDLDGFGGTALGLMFPVIAAFIGFSIADKLAIVPGLVGGM
                     IAKDIGAGFLGALAVGLIAGYTCLFIKNHVKLPKSAASIVPIFIVPVFGTLITVVLIN
                     YVIGIPFATLNTGLENWLNGLSGTNQILMAAIIGAMMAVDLGGPVNKAALTTSLALLT
                     SGIYAPNTAAMVGIVIPPLGLGLATILAKQKYNKQLREAGKSSLIMGLIGVSEGAIPF
                     AVESPLKVIPSCVIGTAIASAMAVGLGSVNATPISGFYGWFTVENWPMYVLSIAVGTV
                     IVAGLVIVLRGNPVIEDDEFEDDDFDEAEWES"
     gene            20143..22743
                     /locus_tag="OE968_002299"
     CDS             20143..22743
                     /locus_tag="OE968_002299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HCP7219576.1"
                     /translation="MIKAHIVNHTHWDREWYFTSGDALVLSEQLFTDVIDELERNPDV
                     SFVLDGQLSILDDYVQLHKEKIEIIKKLIKEDRLHIGPWFTQTDAFFARGESILRNLM
                     IGIFESKKYGKYMKIGYLPDTFGFNAQMPILLKHVGLDNIFFWRGIHLGKQVQSPYFK
                     WKSLNGESYIYAVNMPHGYGTGMLLEPSLKYVNGRLDPAIDFIKSYTDVDEVLIPSGN
                     DQLNIIGDFKNKIKAINDIGKYSYITSSYQEFLKYIKSIESLESYRGEFREPVLARIH
                     KSIGSSRMDIKLACDKLENKLIKRIEPLLVIAKKSKIEISNQLLINTWKKLLEGQAHD
                     SLAGCVTDTVTDDILHRIREANEICDSIENTIVKKISEGLKLSKNDILVFNTEAKRFN
                     GYKEIQVVSDSKNIYFKDNLDATIIEETYVKPRENVLEETPAGNIFIEEPGYYILKVR
                     INVQLPALGYKVVSFELSDKEMVSLDKSNDTFISNDNYKIIYEDGSLNLQLKDGTYIS
                     NFLTLKDSGNAGDTYDFSPLKNDENIKLSFDKVYTEKALGYEKMVVKGTTLLPLTLED
                     RKNKYLNGKLNVKVSIVLSKENPLMDVKLCVDNTIYNHRLRVHIKTDIKDNKNIASLP
                     FGYITRKNGVLDNWEDIYSEMPIDLEPLESNITLTNQNRSCTVFTRGIKEYQHIEDEI
                     ALTLLATTDELGKPDLLYRPGRASGDTTKKGHIRIKTDKAQMLKELEFSFAIYMDSKS
                     FDELEIANLTHNYLRECVNYQLQDYNFFLYHIDNKIQKSIVNKTVSRELEIISLPENY
                     LISACYPSYYSKDKFIIRVENPSSNRMILDEQIFKNRNGKIVNAIEDVEEEQVYEIAP
                     FDVISILLDL"
BASE COUNT         9075 a         2357 c         4061 g         7581 t
ORIGIN      
        1 aaaatgtcga ttgattttaa ataattaaat atacataaga aataattaaa tatctttcaa
       61 tgaaaatatg ataaaatatg acaaattaat tgatgacaat aaaaaatatt ttgttattgt
      121 agtattatag ggtaaattgc aaaatatata cgaaagtaaa attttaaata ttgacattaa
      181 attaaatata ctatactatg taagtgtgat gagagaattt ttttagaggg gatttatagt
      241 gaatataaaa aagatattta ataacaatgt agtagtaagc tccctagaag atggcacaga
      301 aataattgtc actggtgctg gagtaggatt taagaaaaaa gtaggcgatt tgatagatga
      361 aaatttgatt tctaagaaat attttgttca agacgatcaa agggacaaat acaatcaaat
      421 acttaataag acctctattg aatactttaa aatttcagaa gaaattatag aaaaggctaa
      481 tgaagtttta aatactcaag tgaatgattc aataatatta gccttaacta gtcacataga
      541 atttgctgtc caaagagaaa aacaaggtat aaaattacca aacttaatat tgaatgagac
      601 aaaacaactt tatagggaag aatttgaatt tggattatgg gcaattgatg aaattgaaaa
      661 aaggatagga ataaaattgc ctgaagatga agcaggatat attgctattc acataatcaa
      721 tggtttggaa aattctcaaa aagatgaagg tattaatata ctagagtttt caaaacaagt
      781 tattcagata attgaagaag tacatggatt taaattggat gtaaattcat taaattatac
      841 tagacttata actcacttaa agttttttgt tcaaaggatt ctccgaaaag aaacttacaa
      901 tgatagtgat attgaagata tgtataagtt agtgaataaa aattacaata aacctaaagt
      961 gtgtactgaa gaaattgcag cattggtatt agacagattt gaatataaga ttagtaaaga
     1021 agaagaatta tatttaatga ttcacataaa taaaataaca aacagtggtt gttaggattg
     1081 taactgataa agcaggcaaa acctaagtca ttgagcttaa ctattagatt aagttttttg
     1141 atttaggttt ttttattaga tacaatcaaa atacagacag tgacttttag gattgtaact
     1201 ggttaagcag gcaaaaccta aatcattgaa tttaactatt aggttaagtt ttttgattta
     1261 ggttttttta ttagatacaa tcaaatacag acagtgactt ttaggattgt aactggttga
     1321 gcaggcaaaa cctaaatcat taaacttaat tattaaatta agttttttga tttaggtttt
     1381 tctataaatt tgattatgtt tttagataaa aataggaggg gaaaattatg aaaaaaaata
     1441 agttaggttt atggaacttc ttccaaatgt taggaaaaac gtttatgttc ccaatagcac
     1501 tacttagtgt ttctgggatg atgctaggac ttggggcagg ttttacagac cctaagatga
     1561 ttgaaatggt tccattttta gggaatgaat atgttaactt agttttaaac ttcatgttaa
     1621 caataggatt atttgcattt aacaacttgg gagcattatt tgcaatggca attccactag
     1681 gattattaaa aaaagaaaaa gagtttggtg ctttttcagg attagtagga tttatagcaa
     1741 tgcatatagg tacaaatttt tatttaacaa gagctgattt gttagtacca gcagaacaga
     1801 tgtcaactaa tggtcaagct atgattatgg gtatacaaac atataataca agtgttttag
     1861 gtggtattgt agcaggatta attgtttatg caatatatga taaagttagt aatttaaaga
     1921 taccagaatc attaggattc tacagtggac caagattagt tccaattgtt agtttaatag
     1981 ttatgagtat agttggatta ttaataccta ttgtttggcc accatttttc aatgcattcc
     2041 aaagtttagg aagatggatt tcttcagcag gaccattagg atatttttca tatgcagtgg
     2101 cagaaagagt tacaattcca tttggactaa atcatcttgt aacatctgta ttccgtttta
     2161 caccaatagg tggaactgct gttattgatg gagaaacgta ctttggtaca ttgaacatgt
     2221 ttatggcata tgtagaaaat aatcagatta tacctcttga tttagctggt aaaatggaac
     2281 aaggtaaatt gatgattcaa tatggattag ctggtgctgc attggctatc taccgtacag
     2341 caaaaccaga aaatagaaag gcacttaaag gacttttaat atcaggagtg ttgacagtta
     2401 ttataggtgg tataagtgaa ccaatagagt ttctattctt attcatatca ccagcattat
     2461 ttgctttcca tacatttatg aatggtatag caaacatggt acttccatac ttaggcgtgt
     2521 tgatgggatt cacaggagat ttaattgcat ttataagttt tggtgtgtta agaggaacag
     2581 ctacaggatg gccaatagca gtattagtag cagttttata ttttgcaata tactattttg
     2641 tatttaagtg ggcaattatt aagtttaata taaagacccc aggacgtgag gataaagaaa
     2701 taaaagtatc tgaaggaaat ggttcagatt tcaaaaattt gtctacatat aaaggacaac
     2761 aaatgatatc tgctttaggt ggtcaatcta atatattatc actagataat tgtgtaacta
     2821 gattgcgttt aaaactacaa gatgtatcat taataaatga ggatgcaatt aaagaggctg
     2881 gtggtatagc agttgttaaa ttagatgagc atacaataca agtaattata ggaactcaag
     2941 tgtattcttt aagaaagcag atggataaag ctatggaagg tcatttggag gcatgtaatg
     3001 attaattttg ataaaaaagt agaccgattg ggtacatatt gtacccagtg ggactatgta
     3061 gaagatagat ttggtaagaa ggatttgctt ccttttacaa tttcagatat ggatttagag
     3121 tttccatttg aaataacaga ggtgttgcag gaaaggttaa atcatagagt tttgggatac
     3181 agtagatgga aacatgatga ttttagaaat tcagttacga attggtatat taaaagattt
     3241 aattgtagcg ttgatagtaa ctggatatat tatagtccaa gtgtaatgta ttcaattagc
     3301 aaacttattg agatgttaag taatgaagga gatggaatcc ttataaatac tcctgcatac
     3361 aatgcttttt atgatgtgat aataaataac aatcgtaata ttataaagtc acatcttgta
     3421 aataggaatg gattctattc aattgatttt aatgattttg agaaaaagtg taaaaaatct
     3481 aagatattta ttttatgtaa tcctcacaat ccaactggta gagtatggag tgagttagaa
     3541 cttgttaaga tgataggaat ttgtaagaat aatgatgtca agataatatc agatgatata
     3601 cacatggata ttgtatatga caatagaatg acacctatct taaatgttgc aaaggactat
     3661 ttagattctg tattcatttg tacatcagcg tctaaatctt tcaatatacc agcattgact
     3721 gggtcatatg tgattatacc aaatgaaggt attagaaata aatttgaaaa tatcactaga
     3781 taccgtgatt ttgtaaattc gccagcaatt ctagcaatat tagctacaat ggtctgttat
     3841 gatgactgcg aatattggtt agatgaacta ttaaaatacc ttaaagagaa tcttaaatat
     3901 acgattgatt atataaaaga taatttagaa ccattgaaat tggtcatgcc agaaggctgt
     3961 tactttgctt ggatagattt ttccgaactt aaaataagtg gtgagaaatt ccaaaaatta
     4021 ttgatggata ttggagaagt tgctattatg tcggggtctg tatatggtga agaaggtgag
     4081 ttttatttaa ggttaaatgt ggcatgttca agagaaaaac ttgaagatgg tttaaatagg
     4141 attaaaaaaa ctatggatta tattgcaaaa agaattttat agtaggaagg gagatagtta
     4201 tgggatattt aaaaacaatg gttgatgtta tgactactga aatgaatgcc ataagatgtt
     4261 taatagatga agcaggaata gaatatgaaa gtatagttag tgaaattgca aattgtgaag
     4321 gcaaagtaat ttttatgggt gtaggaaaat ctgcacatat aggtaagaaa ttggcagcta
     4381 catttgctag tactggtaca cctagctttt ttgtacatgc aacagaggca gtgcatggag
     4441 atttaggaat gattgaaagt aaggatatta caattttaat atcaaatagt ggaaattcta
     4501 tggaagtggt aaactgtata aaatatatta aagcaatagg ttctaagaca attgcattta
     4561 cttcaaacag aaattcagta ctggcaaaag agtgtgatta tgctttaata tatcctgcaa
     4621 aggatgaagc agaccattta aatctagcac caacaacatc atctacaatt actttggttt
     4681 taggagattc tattgcatgt gcattatcta agagtagtaa ttttggttct tcagattttt
     4741 ataagtacca tccaggagga agtttaggtg agaagttaaa aacagctaac aatggataaa
     4801 agcaaaaagg agagtagttt ttatgttcaa aatgtttaaa aaaaaatcaa taaaatcacc
     4861 catatcagga aaagtaatag agttatctaa aatacaagat ggtgtatttt ctcaaaaaat
     4921 tatgggagag ggtgtagcta tagattctac aggagacatt gtatatgctc caatcaatgg
     4981 aaagatagta gtagtagcag agactaaaca tgcatttgta atagaattag aaaatgggat
     5041 ggaacttctt attcatgttg gtttagatac tgtaaattta aaaggcgaag gttttgaggt
     5101 attggtgagt atgggagaac aagtgaagga aggaacacca atgttgaaaa ttaaccgtcc
     5161 tttgattgaa tcaaagggta tatcacttat tactccagtt acaataacta atcattcaga
     5221 gtacaatatg aatacatgta atgtaggcaa tagtgttgaa ggtgggaaag atactgtaat
     5281 tgagtttaaa taaagaacta aaatacaagg ttaatattta taaataccta taaacttatg
     5341 ttttataaga ttgattgtat agatttgttg tatagatttg ttgtataaaa aagaactctt
     5401 taattataaa ttaaggagtt cttttttatt ttgtaaatat tgtttagatt tatatagaaa
     5461 aacacttagt aataaataga ataaataagt atttatatag ctaaaaatct aaatagtttt
     5521 gtttaaatat atttttatat tttgtaattt caaattaata aataattaga tttaataaac
     5581 aaaaaataaa aatgttgatt atattaataa actttaatat aatatattta tgaaaaatgt
     5641 aaactgtgaa atggaggtag taacatgaaa attgaaaatc tttctattga tgatattaaa
     5701 cgaggctata tatttaatga tgatttaaat tgttatagtt gcattaaatg tacaaaaaca
     5761 tatgaggtag gagaaatata taaaataggt aatagattct ttgaagcttc aaaagctatt
     5821 gaacttcata tggaattaga acatagtgat tatttagagc aattgcttaa tagtgattca
     5881 aaatacaaca cattgactga aaatcaaaaa caattatttc aattatttat tagtgattta
     5941 ccagataagg agatagcaaa acaggttgga gtatccacat ctactatacg ccatcaaaaa
     6001 tttattttca gagaaaaagc aaaacaggct aagctctatt tagcactata tgaatctgta
     6061 tttgaagata aatctaataa aagtagtact ataataccaa tccatgaaca tgctcgaatg
     6121 gtagatgaaa gatatgtagt aactgaagaa gagagaaaac acattttgga tacatcattt
     6181 gaaagtatga atcctttaaa attaaaagta ttttcttcaa aagaaaagaa aaaggtcgta
     6241 attttatcta agattttgga acaatttgaa cgtgggaaga aatattcaga aaaggaagtt
     6301 aatcagattt tagaatctat atatgatgat tttgcaacaa ttagaagata tctaattgag
     6361 tatggtttta tgagtagaaa taaagaatgt acaaaatatt ggttaacata attaaaataa
     6421 taaattttac taatgtgtaa tgttattttt atctaggggg aggagtcaaa tatgaatgat
     6481 gaattaaaat ctattttata caataaaggt gtagacattg ttcgctttgt tgatatatct
     6541 gaatttccaa taaatcaaac acaaggtttt tctaaagcaa ttttattttg tatagggtta
     6601 tcaaaaaaat ttattacaga tatatacaat aacttaccta cagatagtga tgagtttttg
     6661 gaaaaagagg agaaagtaga agaattagct gactggattt caaaatatat tcaaaataaa
     6721 ggatatagag catattctca atcggagaaa aacaatctag aacatggata ttttgaaaaa
     6781 gcctatatta atccagaaat gcaatcaggg attagtcctt taccacataa gacaatagca
     6841 aatattagtg gcattggatt tatgggaaaa aataatttgt ttgtaacaga ggaatatgga
     6901 tgtgctttta gcatgtgtac agtacttaca gatgctccaa tttctgttga aagatatcct
     6961 ttgattgatt caaaatgtat ggattgcaat gtttgtgtag agaactgtcc tgcaaaagct
     7021 atacatggaa atgaatggac tttacctgga aaaagagaat ctattattga tgtttcaaag
     7081 tgtttttgtg tattgaggtg tatgatgagt tgcccatggt cattaagata tgcaaatcaa
     7141 aaataacttt actagagaag gtattaaatt gaatattata aaatttttaa aatgtaagat
     7201 tatataagat ttctcaaaat aaaaatttgt atagaacact cagaaatgag tgttttttta
     7261 ttgggattaa attatattga tacaaagctt aactatttta atcattatat aaaatttgta
     7321 ttaaaaaatt aagaataact tggtaatagt gaaaatataa tgagattata attgatttat
     7381 aatataacta taatgatatt gtaaaaatga aaattgtcct ctcaaaattc ccaaagagag
     7441 taaaagtcac ttcagttata gtcaaaaaaa tttttctgtg aaaagaattt agatttgaaa
     7501 aggaggaatt aatcatggaa attgaaacta aaactccaga ttggattaat gtactagaat
     7561 taaacagtaa aatagatatt actgggaaat atgatgtaag taatatgata caaaatattg
     7621 tctctgataa gtcactagaa ggttccatta tatattttcc aaaaggtaat tacttatttg
     7681 agaaaggtat taaaattagt caacaaataa cacttcaagg agattcttat tatggaggag
     7741 gtaatcaagt atcaaattta gataaaaaac aatcaatcat aggaacaacc aattttataa
     7801 cccgaggagt ttctaatatg agtattatta cattgtcagg aacaagtcaa tgtatcaaaa
     7861 atattaattt ttattatgat agtcatgata tagagaaaat accgcctaaa aatgtatctg
     7921 ctattacaga atatggagaa acacaaggac tatctcattt tgaacatctg tttatttctg
     7981 gattttcagg gataggaatt gaaattccat actattcaac tggtaatgat attactgtta
     8041 gttcatgtgg tcttggtatg aggcttggag agaagtcaat gctttctagt agcaagattt
     8101 acgaatgtaa aaatggaatg gagattacta ctggtgttag cttaaataat gtgagaatag
     8161 aagaaataaa agaaataggt attaataata aaggatttgg ttttaacctg attatgaatc
     8221 ttatggtcga ccaatgtgga tattgtggat ttatgtttga aaaaatgtgc tatagccaga
     8281 taactgccag aattactaga tgcggtcagt attataaaag tgttgattat aatgcttatg
     8341 agaatatgga agataggaaa gaagaagctt attccatttt ttatggagat attttagaaa
     8401 attgcaatat tgtattgatg aatagtaata ttgatacctt ggaaaatgat tcacttgatg
     8461 aacataagat atatgtaatc aaggcaaatg aaacaaacaa tgtaatgcta acatgttatg
     8521 ctgaagcaga taactttata caatgtgcaa agggcaactt gctgttagaa aatggtgaaa
     8581 atacttataa attttataat ggtgagattt gttctgtagg aggtgttcaa atttctgata
     8641 tagatgaaaa agatttaatc aaaataatag agaacacttt gtatatagat gataaaggta
     8701 agtatttaat ggttcctaga ttaaaaaaga atactgtaat atattcagta ctagattcta
     8761 cagaagaaat aaataaatta catggtggaa tatgggaaca gattgatgta aaagtattag
     8821 ctggggaatc catgtactat tataaaaaga taaaagatta aattatcaaa ctaggaggta
     8881 gtgattaatg gaagagtcta taataattaa agatataagt ggctggatta atgtccttga
     8941 ttatggaatt tgtaatgatg aaacaaaaga tgtaagtttt aagttgcaag agattatgga
     9001 tgctgtacca gaagattcta ttatatattt tccaaaagga aaatacttat ttgaaagtgg
     9061 tgttaagatt aagaaacgat taactttatg tggagattct tatattttgg cgaatgttcc
     9121 taaaaatact gctggagtaa cacaatttac ttttaaagga aagaaaaatc ctaaaagtga
     9181 aaatatagca attataacag caaaaagtgt aagacactgt attaagagca tttgctttta
     9241 ttcagatagt tgtgatagag atatgacatc taatcatgaa cctccaacag atggaaaacc
     9301 tagatttcat cataatgtaa ttataaatta tagaaatata tcggctattg tatgtgaaga
     9361 taaacaggga gaatcaggtc attataaaaa tctatctttt agtggttttt ctggaattgc
     9421 acttgatatg cctaataatt ctacagcaaa tgatattaca atttttacat ccggacttgg
     9481 aattagtaca ggagaaaatt caactattgc taacagtaag gtttggggct gtgttgatgg
     9541 aatgataatt tctactggaa cttttataaa tggtatgagg gtagaagaaa taaaaaaagt
     9601 tggaattaaa aatattggta gaggtttaaa ttttattaca aatatcacaa ttgaccaatg
     9661 tggatattgt ggagtttggt ttgattctat atccaatgtt cagatatcag gaaatatcac
     9721 aaggtgtggg cagtactatt atgatgtaag ctatgataat tatttaatgt tggataatag
     9781 agttaaagaa gcatattctt tattctatgg taatttattg gaatcaagta atatagtttt
     9841 atcaaatacc aataaagata attgggaaga tttcaaagaa gataagcata aggtgtatct
     9901 tgtagaagca cttgaaacca agaatgtact attaacatgc aatatagatg ctactgactg
     9961 gattgttaag tcagaaaaag gaaatttaac gtacaataat atgcgacaaa ctgttatatt
    10021 ttacgatgga aaactaagta gtatcaatgg aattggtata tctgatgaag attatgggga
    10081 taaagtcaag ataaaaaaag gaaatatata tataaatagt aaggataagg atattaagat
    10141 gcataaacca gaggtaggtg acattatgtc aacaattatt aaagataaaa gtattctttc
    10201 tgctcattat gggggaacat gggagaaaat tggtgaaaaa atagagtttg gaataactgt
    10261 acactattat aaattgatag agaaataagt aaatacgtag tatttgaata gatgtatttt
    10321 attggagagc taggactata gttttaatgt aaatggtttg gtaatagcat ggattgaata
    10381 atataaaaat aatataaaaa attaatttga ttatgtaaaa ttctatgaag tagtaaaact
    10441 gtgactttag tcataggagg ttcaaactaa gtaaaaggga aaggaatata taatattatg
    10501 gaaggaagaa ctgggattaa agatggaaga tggattaatg tagtagaaag aggtattaaa
    10561 aatgatggtt cgtacaacgt aggtcctgct ttgcaggata ttattgatga aatagaaaca
    10621 gatttttgtg tcttatattt tccaaaaggt aaatacctat ttacaagtgg tgttaaaatt
    10681 aataaagaaa ttgtattgca aggtgattct aattcatcta caggcactac acaatttata
    10741 actcgtggag tagaaaatat gagtattatt acattgacag ggaaaaaaca atgtattaaa
    10801 aatataaatt tttattctga tagttgtgag atacaggtaa ataaagaacc accgacaaaa
    10861 ggtaatccta aatatcatta tgagatgatt attaataaga atgaaaagaa tgttgagatg
    10921 aataatgtat cagcaatcct gtatgataac agtaagaata tgattaaagg tctaggtcat
    10981 tatgaaaata tttatataag tggtttttcg ggtacaggaa ttaggatacc atattactca
    11041 attgtaaatg atattacagt ttcatcttgt gggctgggta ttgatacagg aatagacaca
    11101 attatttcta atagtagaat atctaagtgt caaaatggaa tgaggattag aactggaact
    11161 agtataaata atgtaaggat tgaaaaaata cagaaagttg gtcttataag tagtcaagtt
    11221 aaggggtatg aggggtatgg aagttataaa attaataata ttacgattga ccaatgtggg
    11281 tattgtggct tttcatttga ttcaatgaaa gatagttatt tttctggtat tataagaagg
    11341 tgtggtcagt attattataa tacagattat gacacatatt taagtattaa agatagagta
    11401 gaagaagcat attctttatt ttatggaaat tattttacag aatgtaatat tgatttagtt
    11461 agtgataata aggataactg ggatgatggc ttagaatata aacataaagt ttatgtattt
    11521 aaaacccttc aaataccaaa attaacattg agatgcaata tagatgccta tgattatatc
    11581 gttaaatcgg tacatggagg aggtaattta atgttaaaaa ataattttaa caattatata
    11641 tttattgatt catctaatcc agaagttatt aatggaatta attttaatta tcaaaagaat
    11701 ggaaacttgt taaggttaaa taatggtaaa ttaagttata aaaatggaaa ggaagaaaca
    11761 gctatattca gacctaatta tggtcttatt gtagcatcaa cagattcaga atgtgaacaa
    11821 atagagacta gctatggagg aaaatgggag aagcttggtt ctgaagtaat tggagaagaa
    11881 acggtatatt attataaaca tcatgaacca gataaaacaa accaaataca ataaaatttg
    11941 tattatataa tgatataaag ttttaatata tagtgtttac ctttaatgta atattggtat
    12001 atttgtatag tattaaattt gttaaaaagt aaaattgtag ggtgcttgaa aatagcacct
    12061 tttttagttt cattataaaa ttagttttga aagtttagga ataatgtata tttattttta
    12121 aagaattata accttattaa ggatatttta aatgctagaa atgaatcagt aaatcatact
    12181 ggaattatct taaatgtttt gattaaatta agtatttaga gctataatta tattaaaaat
    12241 atattagaac ataattatat tactatggag gttaaatatg atagtaagtg tgagtagaag
    12301 aactgatata cctgctttct atagtaagtg gttttttaac agacttaaag aaggttttgt
    12361 ttatgtaatt aatccaatga atccaaaaca ggttagtaag atagagttaa atccacatac
    12421 tgttgattgt tttgtatttt ggacaaagga tgtaactcca atgttatatg atttaaataa
    12481 attaaaagac tataaatatt attttcacta tactataaca tcatatggaa aagaagtaga
    12541 gacatgtatt ttagataaaa gaaaggtaat agattcattt aaggaattgt ctagaaaaat
    12601 aggcaaagaa agagtaattt taagatacga cccgattttc ttaagtgaaa agtacacagt
    12661 agattatcat atcaaagcat ttgcgagttt atgtaatcag cttgatggat ttacagaaaa
    12721 atgtataata agttttatcg atttatataa gaaaacaaaa tttaatacta aagcattaca
    12781 tataaagcca atagaaatta cagaaataga aacattatca aaagagattt ctaagattgc
    12841 tcataagcat gggataacac ttgaaatgtg ttctgaagaa tataatttaa gtaaatttgg
    12901 gattggaaaa agtaagtgta ttgatgatag attaatatca aaaattatag gatgtgaagt
    12961 agaggtaaaa aaagatagta cacaaagaga tatttgtgga tgtgttaaaa gtgtcgatat
    13021 aggacaatac aatacttgca gacattattg tctgtattgt tatgctaact ttaattatgc
    13081 aaaagtagaa gaaaactgta ggctttataa agaagataat aaattactca tagatacttt
    13141 aagagatgat gcaaaaataa gcattagaga tatgaagact attaaagtag ataagaataa
    13201 acaaattagt atatttgatt aaaataaata tactaattac cttaatatat taagaatata
    13261 gatacttttg ataacaaaat taaacttaat agatattttc tatataagaa agatggtcat
    13321 aatatgtcaa tttgaccatc tttttgatat aattaaaaca caaataattt agtaacaaag
    13381 gaggcagaac ttgaatttat taaaaaaata tcctatacct attgcaagtt tgattttgtc
    13441 aatctttact ttaggtaact tattacaatc ttatagtgaa tcattacgta atgtaattgg
    13501 atttatagga tttattttgt atgcaattta tatagtcaaa ataatattac ttagaaaggg
    13561 tgttaaagag caattagaga acactttaat atcaagtaca tttccaacta taacaatggc
    13621 aacaatgata tttgctacat atataaaacc attatcttta gaattaagta ttatgatttg
    13681 gagcatagga attgtgggtc atcttgtgtt aatagtctta tttagtaaga agttcttagt
    13741 taaattctca ataaaaacgg tatttccatc ttggtatata gtatatgttg ggatagttgc
    13801 agctagtgtt acggcaccag catttaatca acttttgatt ggcaaaattg ctttttggat
    13861 aggatttgta tcttatatag ttcttatacc agtaatttta aagagagtat ggataatcaa
    13921 ggaaatgcct gaaccatctt taccaagtat agctatatta gctgcaccag ggtcactatt
    13981 attgtctgga tatattaatt ctttttcaga taaaaataat gtagtattat acttgttatt
    14041 catattatca attgtatttt atattatagt tttgggatat ttaccgaaat tattaagatt
    14101 gcctttttat ccgagttttg ctgcatttac atttcctatg gcaataagtg caatgggtat
    14161 gaaactaatg aatggttatt taactaaatc aggtcatttt ataagttgga tttcatatgc
    14221 ttctaagtta gaagagataa ttgctacagt gattatttta tatgttttag ttttgtttat
    14281 tatatatctt agtaaatctg aaactacatc taaagctaaa taagaattat taaatatgtg
    14341 tatttaatag gaatattgat ataaatatat gaagataaga taaaccatag aaacttaatt
    14401 tagcttaatt ttattggagg aaaacaaatg aaaacaaaag aagaatattt aaaagaagtt
    14461 agaaacatat cagaagaata ctttagaaaa ggagagtttt tttgctctga agcagttctc
    14521 cagacaataa atgatgcttt aggccaacct ttaagtccag agataactaa gttagcatca
    14581 ggatttccga taggacttgg aaaggcacaa tgtctttgtg gagcaatatc tgggggagag
    14641 atggctttag gtatagtata tggaagagtt catggtgaag ctatgaatcc aaagatgttt
    14701 gagcatgcta aaggtttgca tgattatatt aaaaaagagt atggtgcaac atgttgtaga
    14761 gctattacaa agaaatggga tggtgataac tttatgtctc ccgaaagaaa agagcactgt
    14821 attaaaataa caggtcaagt tacagagtgg gttgcagata agcttataga agatgaaaaa
    14881 cttaatatca aatagtgtaa tattagttgg tgaatttata aagttaaatt tacttatagt
    14941 ataagatact tgatattctc gtattgatag aaaaatttat agcatatgta tttaatgaaa
    15001 tatacttata tttagagtgt ggtttaattt cataaataca tatgctatta ttttaagtat
    15061 ataagcaaat ttatttaaat aaatagaaac agttaattta tatgtacaaa actatatatg
    15121 attagtgtaa ataaatacct attttataat actcaacata aagacaccag acatgattag
    15181 tattatacca ataaaaatag caagccattc ttttttgttc ttcttttctt taaaaaatat
    15241 aatccctcct aaagtggcta ctatcacaca actctgagag atagaaaaac ttattgtaac
    15301 tcccaatgta ttagtcgtta tgaacatacc taaatttgct attgaccaca atataccagt
    15361 aattaaattg aataaaacat tttccctata tacaatctct ttagaaaaat acttgacaat
    15421 aatagatgaa gttatcaaca taccaacaga ttgaggtaat ataattctat atccttcaat
    15481 taaaaatatt tgattagtta caacatataa tgataaaaat agagatgata ataatacaac
    15541 tccaacacat tttaacatat ttttatctgt agatttttta gtttgataat ttgtgagaag
    15601 tataccaagt attatacata atattgataa agaaccaatc agtaacattt tagaactggt
    15661 ccattcatta aacaagatta cagctaataa tgtcgtaaaa gttaattgtg aaccatttga
    15721 aattggcatt actttagata cactagcaat ttgaattgct ttaaactgca ttaattgtcc
    15781 caaactccag aatatgccag aaatcatact tatacaaaat gaaaaaaatg taatttcagg
    15841 atgtataacc agagttatta tagtggaaaa tataaacgca cttatggatg tacctaaaag
    15901 ctgttcatga ggagaacttt tctttagatt tgcaactatg ggcatcaatc cccatcccat
    15961 tacaggaagt aaagcaataa ttattgtcag cattaaacta tttcctttca tattaaattt
    16021 agacagcttt taatttatca tctaaaatta aagtgttcaa tacataaaaa ttaccgtatt
    16081 taatcaggaa atattagtag ttttttagaa aaacattttc cattaaaata aagacaaagg
    16141 gaaggagtaa aattgaaaat gttaactgat atgattcaaa atcgtgaaat taaaataata
    16201 aagtttttat taaaagaagg tcatacaact gtaaaagcaa tagcagatga tttagatgtt
    16261 tcagaaaaaa cagtttcaaa atctcttaaa gaagtagaag cagtgcttaa aaagataggt
    16321 ctttctttaa taagaaaacc taagataggt gtttatattg atggagattt aaaaaaaata
    16381 cttccttacc tagataataa aggaagtcaa attcctacaa ccagagagga gagagttatc
    16441 tatatatatt cagtactttt aaagagtaat gattatatta ctatacaaca actttctgat
    16501 gaactatata taagtcgtgg aactattgaa agggatttag cagaagttga aaaactgcta
    16561 aaaaacgaag ggatttccat atataagaaa cctagtaagg gaataaagtt aaatataagt
    16621 gaaagagata aaagacaact tactgctaag tttatacata aattttggag tagaaactgg
    16681 tatattaagc aagagcaaga aagcttttat caagcatttg aaaagataca agcagatgta
    16741 aatggtattt tttcggaaga tgatttatca ataattattg atattcttag gaatttcagc
    16801 agagaaagaa aatttgagtt ctctgattat gaatttcagt cattagttat tcatttggca
    16861 atagctgtag agagaattag aaaaggcgaa tatatagaag aaagtttgta tactggtaat
    16921 atagaaaata atcaaatgtc aaataccaat tatttagcaa aacaattaga agaaaaattt
    16981 tcaatattat taccaaaatc tgaaattgga tatataaatt tacatttagt agcgtctgac
    17041 caacatagag atactaatga actaaaaaat acttcaacta atccttgtga gacaagtaca
    17101 aataatatat caaatcttcg ggaaattata aaaaatacat tgtatgagac agcttatgac
    17161 aaggatttaa ttgatggatt gacttcacat gtacattcat caataaatag actgaaatat
    17221 ggacttagta ttaaaaatcc atatgtaaat acaatcaaac aaaacttttc tttatcattt
    17281 gagcaagctt tagatttaaa gaaagtaatt gaatttatat atgatattag gataaatgat
    17341 gatgaatgtg cttatatagc attacatttt gaagctttta gagaaagaat gaaagaactt
    17401 ccacaaaata ttagagtaat tctagtatgc agtacaggat taggttcatc taggttattg
    17461 tctgcaagaa taaaaaaata ctttccaatg ataaagattg aaaaagtact ttccgtacaa
    17521 gaattagtat ccagtaaaat tgatgcagat ttagtaataa gtactattta tttagagtta
    17581 gaaacaattc caaccatagt agttagtcct attttaaatg aaagtgatat aagaaccttg
    17641 gaaagaaata tacaaaatgt ttcaagttgt acttctaaga agtataaatc tttcagaaac
    17701 ttaatctttg aagaaaatat attgttgaat attgaagctt caaactatga agatgcaatt
    17761 aagtatataa cagataacct aataaaaaaa ggttttgcaa aagaaggtat agctaaaagt
    17821 gcaattgaga gagaaaattt atcttacact tctttccaat caatagctac acctcatgct
    17881 aatcctagtt atattaaaaa atctaatata tctgttgcaa cgttaaaaaa tcctattaca
    17941 tggggaaatg aaaaggtgga agttattttc tttatttcat tagaaaatga caaaaaccta
    18001 gagcttgatg aaatatatga agttttttat gactttattg acaataaaaa aaatataaat
    18061 gacatattaa gtgcaacttc cacaaaggaa gtgtacgatt tgctagtgga ggagagtata
    18121 tagtgaaaat atcagatgta ttgaaaaaag agcaaattgt ttttaatctt gatacaaata
    18181 caaaggaaga aacaataaaa aaattaagta gtatatttgt tgaaaatggg attgtggaca
    18241 atgaagaaga atatgttaag tctgttttgg aaagagaaga acattcaact acaggtattg
    18301 gtaatggtat tgctattcct catgggaaaa gtaatgctgt caaaaaatct tctataatat
    18361 ttgcaaagac taagcataag attgaatggg atgctttaga tgaaaaacca gtagatagta
    18421 ttttcttatt ggctataagc aatattgata aggatagcaa tcatcttgta ctattatcta
    18481 aattagcaac taaacttatg gatgatgaca atgtagatgc actaaaatta gccaattcag
    18541 aacaagaaat aatcaatata tttagtgaag aaggagagat gtagaaatga aaagaaaaat
    18601 tatagcagtt acagcatgtg caacaggagt tgcacataca tatatggcag ctcaagcatt
    18661 aaagaaagct tcaaaaaaga tgggtcacct tataaaagtt gaaacacaag gagctacagg
    18721 aatcgataat gagttaacta caaaggatgc acaaattgca gaagtagtaa tatttgcagt
    18781 agatactaaa gtcagaaatg ctgaacgttt tgagggaaaa gaaatactag aagtaccagt
    18841 taatgcacct ataaaggatg cagagaaagt aataaatgat gcattaaagt taattgacac
    18901 taaataaatg gagggaaatg taatgttgaa aaagatagtc tctgagttaa aaaagcatgt
    18961 cttaactgga atctcatata tgattccatt agtaattgca ggtgctatga taatggcgat
    19021 atctcgtgta ggtggttctt tctataatat accagatata tgggatgcta aatatgcaga
    19081 aagtgctagt agtattgtta gattattaca tgatttagat gggtttggag gtactgcatt
    19141 aggattaatg tttcctgtaa ttgctgcatt tataggattt tctatagctg ataaattagc
    19201 tattgtacca ggtcttgttg gaggtatgat tgctaaagat ataggtgcag gatttttagg
    19261 agctttggca gttggtctta tagcaggata tacatgtttg tttattaaaa atcatgttaa
    19321 attaccaaaa tcagcagctt caatagtacc aatatttata gtaccagtat ttgggacatt
    19381 aatcactgtt gtattaatca attatgtgat aggtatacct tttgccacat taaatactgg
    19441 attagaaaat tggttaaatg gattatctgg tacaaatcag atactaatgg cagctattat
    19501 aggggctatg atggcagttg acttaggtgg accagttaat aaagcagctt taacaacatc
    19561 acttgcatta ttaacaagtg gaatttatgc gcctaacact gctgcaatgg taggaatagt
    19621 tataccacca ctaggattgg gacttgctac tatactagca aaacaaaaat ataataaaca
    19681 gttacgtgaa gctggaaaat catctcttat aatgggttta attggagtaa gtgaaggagc
    19741 aattcctttt gcggtagaat ctccattaaa agtaatacct tcatgtgtaa ttggaacagc
    19801 aattgcttca gctatggcag ttggtttagg ttcagtaaat gcaactccaa ttagtggatt
    19861 ttatggatgg tttacagtag agaattggcc aatgtatgtg ttatcaatag cagttggaac
    19921 agtaattgta gctggattag ttatagtatt gcgtggaaat ccagtgattg aggatgatga
    19981 atttgaagat gatgattttg atgaagcaga gtgggaatct taaaatttaa taactattta
    20041 agacgtgtta taagctatat tcaatatgaa tcttatacta aataaagtgt taaatattca
    20101 gtttagactt aaatataaaa gataaagaac agaggagaat aaatgataaa agcacatatt
    20161 gttaatcata cacactggga tagagaatgg tattttactt ctggagatgc attagtactt
    20221 agtgaacaac tatttacaga tgtaattgat gaattagaac gtaatccaga tgtaagtttt
    20281 gtacttgatg gacaactttc tattttggat gattatgtac aattacacaa agaaaaaata
    20341 gaaatcatta aaaagttaat aaaagaagat agactacata ttggaccatg gtttactcaa
    20401 actgatgcat tctttgctag aggagagtct attttaagaa acttaatgat tggaattttt
    20461 gaaagtaaaa agtatggtaa gtatatgaaa attgggtatt tgccagatac atttggattt
    20521 aatgcacaga tgcctatact attaaagcat gtaggtcttg ataatatatt cttttggaga
    20581 ggtatacatc ttggtaaaca ggttcaatca ccatatttta agtggaaaag cttaaatgga
    20641 gaaagttata tatatgcagt aaatatgcca catggatatg gaactggtat gcttttagag
    20701 ccttcattaa agtatgttaa tggacgctta gacccagcta ttgattttat taaatcatat
    20761 actgatgtag atgaggtgtt aataccttct gggaatgacc agttaaatat aataggtgat
    20821 ttcaaaaata aaattaaagc gattaatgat atcggaaagt attcatatat aacgagttca
    20881 tatcaagagt ttttaaaata tataaagtcc atagaatcac tagaaagcta tagaggtgaa
    20941 tttagagaac ctgtattagc aagaatacat aaatcaattg gttctagtag aatggatata
    21001 aaattagcat gtgataaact agaaaacaag ctgattaaaa gaatagagcc attattagta
    21061 attgctaaaa agagcaaaat tgaaataagc aatcagttac ttataaatac atggaaaaaa
    21121 cttttggaag gacaagcaca cgatagttta gctggatgtg taactgatac tgtaacagat
    21181 gatattcttc accgtataag agaagcaaat gaaatatgtg acagtattga aaatactatt
    21241 gtaaaaaaga tttcagaagg gcttaaatta tctaaaaatg atattttagt atttaataca
    21301 gaagctaagc gttttaatgg atataaagag atacaagttg taagtgatag taaaaatatt
    21361 tattttaaag ataatttaga tgctactata attgaagaaa cttatgtaaa accgagagaa
    21421 aatgtattag aagaaacacc tgctggtaat atatttattg aagaaccagg atattatata
    21481 ttaaaagtaa gaataaatgt acagcttcct gcacttggtt ataaagttgt tagttttgaa
    21541 ttaagtgata aagaaatggt gtcacttgat aaatctaatg acacttttat atctaatgat
    21601 aattataaga taatatatga agatggaagc ttaaatttac aacttaaaga tggaacttac
    21661 atatcaaact ttttaacatt aaaagatagt ggtaatgcag gtgataccta tgacttttct
    21721 ccactaaaaa atgatgagaa tataaaactt tcgtttgata aagtgtatac agaaaaagct
    21781 ttaggatatg aaaaaatggt ggttaaaggt actactttac taccacttac attagaagat
    21841 agaaaaaaca aatatcttaa tggtaaatta aatgtaaaag taagtattgt cttatctaaa
    21901 gaaaacccat tgatggatgt aaaactttgt gttgataaca cgatatataa tcatagacta
    21961 cgtgttcata taaaaactga tataaaagat aataaaaaca tagcatcatt gccatttgga
    22021 tatataacaa gaaaaaatgg agttttagac aactgggaag atatttacag tgaaatgcct
    22081 atagatttag aacctttgga aagtaatatt acgcttacaa accaaaatag aagttgtact
    22141 gtatttacta gaggaataaa agagtatcaa catattgaag atgaaattgc attgacctta
    22201 cttgctacta cagatgaact aggaaagcct gatttattat atagaccagg acgtgcttct
    22261 ggtgatacaa ctaaaaaagg tcatataaga attaaaacag ataaagctca aatgcttaag
    22321 gaattagaat tttcatttgc aatatatatg gattctaaat catttgatga attggaaatt
    22381 gcgaatttaa cccacaatta tctaagggaa tgtgtaaatt atcaattaca ggattacaat
    22441 ttctttttat atcatataga taataagatt caaaaatcaa ttgtcaataa aactgtaagt
    22501 agagaattag aaataatatc tttaccagaa aactatctta tatcagcatg ttatccttct
    22561 tattacagta aagataaatt tataataaga gtggaaaatc caagtagtaa tagaatgata
    22621 ttggatgagc aaatatttaa aaatagaaat gggaaaattg taaatgcaat agaagatgta
    22681 gaagaggaac aggtatatga aatagcacct tttgacgtta tttcaatatt attggattta
    22741 taagtgtaaa agtaagttta ttgtttaaag tctgacagat attaatctgc cagacttttt
    22801 aatttgtata aatttgggta aatattaatg aatggtttta gtatttaagt atgaatttag
    22861 tatttaatat agaatttatt gaagtagaat aattagttta acaggataag cagtttaaat
    22921 aaagaattat tatattagag tgattttata tataatttaa aataataaaa ttttaataaa
    22981 atgagttaaa gattgtatat taatagagtt gatgtagtta caaaaaagtt accaattgtt
    23041 atgtatttac aaaactgata tattaattac ataa
//
LOCUS       DAJMZY010000062        22658 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.062, whole genome shotgun sequence.
ACCESSION   DAJMZY010000062 DAJMZY010000000
VERSION     DAJMZY010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 22658)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22658)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22658
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.062"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            <1..305
                     /locus_tag="OE968_002300"
     CDS             <1..305
                     /locus_tag="OE968_002300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCP7219577.1"
                     /translation="GYIDILIVSILEKKDCYGYEIAKQVRERSEFELKEGTMYLALKR
                     MESKNLIKSYYSNEQSSGGRRKYYNLTNEGKDFLEIKKQEWRFIKKVMNQFLGEVD"
     gene            309..1100
                     /locus_tag="OE968_002301"
     CDS             309..1100
                     /locus_tag="OE968_002301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219578.1"
                     /translation="MKLIDEYLDKLYKKCDNKSTIELKQEMRCHLIESANEFKLEGLD
                     EEEACKKAIERFDDGDEMQYELCNIIKELSLSLDRHKSIVMGFKKVLGYISIIAFLIS
                     GFMWYYNNSLQHNMYNLGKELDGEIKQLAERHDMTKIGEYKLELEKILDKDKYSKVKA
                     LRLYVIDMKDGNTNLSSSGLNANMVYEREADYNNISNFIQHLGYNGKDFLDKNGNIVN
                     PDIFLEYFFYFESEMLIPVAFAFGLLCIIAYFILRFKISLIKNNN"
     gene            1664..2746
                     /locus_tag="OE968_002302"
     CDS             1664..2746
                     /locus_tag="OE968_002302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
                     /protein_id="HCP7219579.1"
                     /translation="MKKIRKLATKLLIAMMVLTSCMSVTVYGMTAKDVTAKTPKSYVA
                     GTNSIYGPKLSQAQLNSVAQATADFMNKKITKNMTTDAKIRVAYNHIKNNTTYVNWNA
                     AEGANTAYTLVTKKGACSGMCRSLKALCDAMGIECYYVHSTTNDHQWNLIRFEDGRLY
                     HVDIDANKSAGADIIYKSLTHPLPFDKKAYPAVGEVVKTQNPTPTVKKPTPAKPSAPV
                     GPGNHTMIADQQGAILDEVYGNNLRPKIEMYEGVPCSLINSSINTIKFTSKNSNLDPS
                     KHTVTVIGFMNTPYGMVALAPDGVPDEYPFEYDKPFSLDFTGKNLSAAELSKKCKENN
                     VIIKVEIGETASNSGRGMVAYARYVN"
     gene            complement(2958..4151)
                     /locus_tag="OE968_002303"
     CDS             complement(2958..4151)
                     /locus_tag="OE968_002303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FprA family A-type flavoprotein"
                     /protein_id="HCP7219580.1"
                     /translation="MSKVFEVKKDIYFTGVVDEGLKVFDIIMETEFGTTYNSYLIKDE
                     KTVLFDTVKANFKDEFLSNLSEVTDIAKIDYVVIHHTEPDHAGSLKYLLDINPNIEVY
                     CTKAAKLYLDGQINRPFNCHVIKDGEILNIGKRNLRFITAPFLHWVDTMFTYIEEDKT
                     LLTCDAFGCHFASVDAEVVNSEDYLKSAKHYYDCIVKPFAKHVLSAVDKVVGLNIEFD
                     TILTSHGPMLTKDPMAAVKRYVEWSTEAVNTTNQNQVSIFYLSAYSNTLEMAKKIKEG
                     LDKEGAKAELYDLEDMTLTEMHDTLVVSKVILLGSPTINKTMVKPMWDLFSVIDPMAN
                     QGKIAGVFGSFGWSGEGITMAETLLKSMSFKMPVESLKKKFFPSEETLKECMAFGAEF
                     AKLVK"
     gene            4470..6314
                     /locus_tag="OE968_002304"
     CDS             4470..6314
                     /locus_tag="OE968_002304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03960 family B12-binding radical SAM
                     protein"
                     /protein_id="HCP7219581.1"
                     /translation="MNKVDLKKILKKVEKPARYLGNEINSIHKDTSNSELIRYAHCFP
                     DLYEVGMSHLGSHILYDVINKDEDVFCERVYSPAVDMENIMREKSIPLFALESREPIT
                     NFDFVTFTLQYELSYTNILNILDLANIPILKEERTLEDPFIMVGGPCAYNSEPLADFV
                     DVVILGEGEEVNLEVVNEYKEWKKNKTTREDFLYKISSIEGVYIPSFYDVKYNEDGTV
                     QSVTPNREGITKNPTKRIIKDVETVDYPEKLIVPYIDTVHDRIVLELFRGCTRGCRFC
                     QAGMIYRPIREKSVKRLKEILDKLVKNTGYDEISLSSLSTSDYSKLSELTDYLVDEYA
                     SNNIGISLPSLRLDNFSMEIADKIQQVRKSGLTFAPEAGTQRLRDVINKGVTEEDLEN
                     ATERAFEMGWNSVKLYFMIGLPTETYEDLDGIAKLAYKVIDIYRKVNGGKLKRSFSVT
                     VSTSTFVPKPFTPFQWHGQDTTEEVINKQRHLVNKLRNNNIKYNYHDSKTSLMEAVVA
                     RGDRRIGKVIYDAFRLGAKFDGWAEHFNLDIWKEAMEKNNLSIDFYAHRNRNYEEVFP
                     WDHIDVGISKKFLIREDENAKKEKITSDCRHNCNGCGINIHDIGRGLC"
     gene            6316..7017
                     /locus_tag="OE968_002305"
     CDS             6316..7017
                     /locus_tag="OE968_002305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2344 domain-containing protein"
                     /protein_id="HCP7219582.1"
                     /translation="MSKIIRVKFKKEGDMIYISHLDLQRLLQRAFRRAEINLSHSQGF
                     NPHPKMSYGNALALGTESQGEYVDIEIEEDDLSVEEFLNKVSIQLPDGIDFIKAKEID
                     RQTPSLSSVIDYGEYLFNIDLKRPMTKEFVKRKVIDFMNNKEIIITKKNKKGKMVEVD
                     IRPMIRTFDVLNLEDEHITLTATIATGSKTNLNTNILIPKILEMFELDIDPLDVDILR
                     RDLYVLEDGELVTPM"
     gene            7035..8456
                     /locus_tag="OE968_002306"
     CDS             7035..8456
                     /locus_tag="OE968_002306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rne/Rng family ribonuclease"
                     /protein_id="HCP7219583.1"
                     /translation="MKKIVIESLIGSQKTAVLEDERLTELFVEDNLNKKTVSNIYRGI
                     VKKVIPGIEACFVDIGFKKLAYLQLKKGSTIKSGQDILVQINKEEIGTKGAKLNTEIS
                     ISGRYIVYIPSNDRTTISNKITDEKERFRLKKITKAVNKENLGLIIRTEAQGCTHDEI
                     KKDIEELKLKYENILKEYKLGIGPKLLYKSLDFATKYVKDNVNDDIESIITNSYDKYS
                     ELKSILRGIDKTYVDKLCLEENRDVFDLYRIESKIEKLLNKKVWLKSGGYLIIEKTEA
                     LTVIDVNTGKFIGTGKLDETVYKTNLEAAKEIVRQLRIRDIAGIIIIDFIDMHKKKHQ
                     KEILHILEEEFNKDKRKAEVLGMTKLGLVEVARRREKESIDKYYLMSCPCCDGEQTIK
                     SVHYILDSIEKEIMRISEHTVYKNIMVEFNDFIFEQIKEYYMDIIDKIGEKYNIKISL
                     NANSTLKHNKTNVIFDKIVDNKM"
     gene            8557..8868
                     /gene="rplU"
                     /locus_tag="OE968_002307"
     CDS             8557..8868
                     /gene="rplU"
                     /locus_tag="OE968_002307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012063435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HCP7219584.1"
                     /translation="MYAIVKTGGKQYKVSEGDVLFVEKLEANAGDVVTLNEVLACSKD
                     GELKLGSPVVEGASVQAKVVEQGKAKKVIVFKYKAKKDYRRKQGHRQSYTKIVVEKIN
                     A"
     gene            8883..9200
                     /locus_tag="OE968_002308"
     CDS             8883..9200
                     /locus_tag="OE968_002308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HCP7219585.1"
                     /translation="MIKVKYYYNDDFLLQGFCLKGHADFAEIGYDIVCAAVTSNAIAV
                     INSLDKLQKIEFEKVVGEEGHIECIVKDTHVKDAQLLLNHFQLAVKEIKREYPKNIKI
                     LKK"
     gene            9214..9504
                     /gene="rpmA"
                     /locus_tag="OE968_002309"
     CDS             9214..9504
                     /gene="rpmA"
                     /locus_tag="OE968_002309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HCP7219586.1"
                     /translation="MLNMNLQLLASKKGVGSSKNGRDSISKRLGVKRFDGQLVTAGSI
                     IVRQRGTKIHPGTNVGKGSDDTLFALVDGTVKFERKDKKRKKVSIYPVAIAE"
     gene            9615..10892
                     /gene="obgE"
                     /locus_tag="OE968_002310"
     CDS             9615..10892
                     /gene="obgE"
                     /locus_tag="OE968_002310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000469293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HCP7219587.1"
                     /translation="MFIDKARIFVKAGNGGNGSVAFRREKYVPAGGPDGGDGGRGASI
                     IFEVDLGLRTLMDFKYQKKYQAQNGGDGSKGKRAGKNGENLVLKVPAGTVIRDEATGL
                     VLADLKKEGDTAIVAKGGIGGKGNQHFANAVRQAPAFAKSGTDGEERWITLELKMIAD
                     VGLLGFPNVGKSTFLSVVTKAKPKIANYHFTTLTPNLGVVQTKFGDSFVLADIPGIIE
                     GASEGIGLGHEFLRHVERTKVLIHIVDISGLEGRDPIEDFDKINDELKLYNEKLSKRP
                     QVVVANKFDILEDESKFEKFKSELEGRGYTVFKMSAATRQGIDEVIAYVSKMLKEVED
                     VELVSEEEMYRPELDIGTEEELSIDIEDGVYVVTGKALRRIMYSVNFDDMESLQYFQK
                     AMESQGVFDRLREMGIEDGDVVKIYELEFEFYN"
     gene            10944..11312
                     /locus_tag="OE968_002311"
     CDS             10944..11312
                     /locus_tag="OE968_002311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhbY family RNA-binding protein"
                     /protein_id="HCP7219588.1"
                     /translation="MLKGKQRAYLRSLANTLKPTTQIGKEGVTESFLEQLDGMLRTRE
                     LVKVTILENAGLDTKETANAVCEALRAEFVQAIGFKFTIYKRNIEEPKILFPGHEQAK
                     AKTKNNNVTKKGKPTKRAVR"
     regulatory      11404..11510
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            11613..12818
                     /locus_tag="OE968_002312"
     CDS             11613..12818
                     /locus_tag="OE968_002312"
                     /EC_number="1.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HCP7219589.1"
                     /translation="MKIAILGYGTVGSGLIDLIENNTSKRDIEVVGILVKNKEKHKYK
                     KYFDKITTDIEDIFDKDIDILVEVIGGLNPAFDYVTRALNKKIHVVTANKDLLAEKGS
                     DLIELANLNNVSIKFEASVAGGIPVLKPLIESLEGNNIKSINAILNGTCNFILSKMYD
                     ENLPYDVALKQAQELGFAEVNPDADVLGYDSARKLSILSTLSYGKIVYWKDLLLEGIT
                     SIDEKDIEYAKKLNCKIKLVARSKYESGEVSGFVRPALVDNNNMLSKIDNEFNVVILV
                     GDSVGELSFVGKGAGRGATGSAVYADIIDIIDNRSSNIKSFSKGKLDLSGLIEDECSA
                     VVRFGGYNNKDGILECLDKYVDSYDIIDDEELAIFVSAKSEHEIDRVLEIVKRNNYSE
                     SAKKLLKID"
     gene            complement(13019..13585)
                     /locus_tag="OE968_002313"
     CDS             complement(13019..13585)
                     /locus_tag="OE968_002313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HCP7219590.1"
                     /translation="MATRPIEIDEYKKIMELLHTGFTYSENGVEKRFRKNPKVALALM
                     LEANLGLRISDILRLKIGNFKGNMLEINEKKTGKLQYRPVNKNIIESINEHARKYNLK
                     SNDYLVNIKTKAIQKQLRIICKHLNLYNISTHSFRKLYATTQFEKSNNNLELVKELLN
                     HSSVATTQRYIRVTQQAINEASENFFIG"
     gene            complement(13865..15124)
                     /locus_tag="OE968_002314"
     CDS             complement(13865..15124)
                     /locus_tag="OE968_002314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation integral membrane protein YlbJ"
                     /protein_id="HCP7219591.1"
                     /translation="MKKNKIIAFFAPSIIVGVLVLGIILYPNEAIKSAREGFSIWSNV
                     LVPSLLPFIIGANLIVDLKIVDIIGFIINPITRFVFNVSGKSALAFAISTVSGYPVGV
                     SLASEFRSNGQISKYEAQRLVSFCSTSGPLFIIGSVGTGMFQNSNLGYLMILCHYLGT
                     ILVGLFFRNYGNENLPKTKLDLKTNIKNVINIRNSSGNGFFVLFGNAVFNGVNTLLTV
                     GGFVIVFSVVFKILSLFNVISLIASVIYLPLSFLGVSKELCQAFVSGLFEITIGCNKV
                     SSITSSPEILRASLASFLIGFSGLSILAQCCTFLSKTDIDLKLYILSKFAHGVLAAIF
                     IFILYPIANSAVLVSSFADTYNVIYNNLIWFYYLSYYDTILQIVVIIYLISAVFIAKK
                     HMKTLSTNGKLMRYKNTFFTKKFSRKK"
     gene            15249..15962
                     /locus_tag="OE968_002315"
     CDS             15249..15962
                     /locus_tag="OE968_002315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HCP7219592.1"
                     /translation="MFNSIASKKVYEQVIEQIQYKILNGELKKGDKLLSERELSEQMN
                     VSRTSIREAIRVLETMGVIESRQGEGNFICTNIEKTLIEPLSMIFKLNNGTLEDILEL
                     RIILEIEIAKLASKRITSSEVIELKHIIDEMRVETNKKDNNRVLVLLDQKFHSKLATL
                     SKNYLIQSLFMTASKLFDGFIEDAREKIIAEPFNENILLKQHEAIYNAVVENDVELAC
                     EKAKEHMDFISKNYRKNEN"
     gene            16080..17354
                     /gene="larA"
                     /locus_tag="OE968_002316"
     CDS             16080..17354
                     /gene="larA"
                     /locus_tag="OE968_002316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel-dependent lactate racemase"
                     /protein_id="HCP7219593.1"
                     /translation="MVKLKVPYSKQGMILEIPDERFLGVLESKSDNYIEHKTQEEIVE
                     ESMNNPIGSNSLEELVKGKKNVVIITSDHTRPVPSRITMPIILRRIRNVNPEIDVKII
                     VATGFHRPSTREELIYKMGEEIVDNEDIVMHISTDDKSMCKVGILPSGGDLYINKLAY
                     EAELLIAEGFIEPHFFAGFSGGRKSVLPGIASAKTIMYNHCSDFIDSDNSRTGKLNNN
                     PIHEDMVYAAKVAKLAFILNVVIDKDKKIIASFAGDVEKAHTKGCRFVTELSKVNSIK
                     SDIVVTTNGGYPLDQNIYQSVKGMTAAEATCKDGGVIIMISACNDGHGGQSFYENVAN
                     ADSPKQLLDKIRSVDRVDTIPDQWEFQILARILSKYTVIMVTDKCNPEMIKKMHMKHA
                     FNFKEALEMANSIVGKESKVVVIPDGVSVIVK"
     gene            17371..18159
                     /locus_tag="OE968_002317"
     CDS             17371..18159
                     /locus_tag="OE968_002317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003402402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HCP7219594.1"
                     /translation="MEILTCIKQVPGTTSVEVDETTGVLKRDGVDSKMNPYDLYALET
                     ALRIKEDKKANLKVLSMGPPQAKKVIEESFMMGADEGALISDRRFGGADVLATSYTIS
                     QGIKKMGKVDLIICGKQTTDGDTAQVGPEVAEFLDIPHVTNVTKLIEVKDESIVVEID
                     MPNDLQVCEIEYPCLITVEKDIFQPRLPSFKLKLNTKDREIPVYSLDDFEDKNENNYG
                     LNGSPTQVVRIFPPKPNTDKNIVRGNADELSFALVNKLEELKLV"
     gene            18173..19393
                     /locus_tag="OE968_002318"
     CDS             18173..19393
                     /locus_tag="OE968_002318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding protein"
                     /protein_id="HCP7219595.1"
                     /translation="MSKIVVNQDKITDLKRILEICPFGAIEEKSGIVEISAGCKMCKL
                     CVKSGPKGAFEFIESSKVQINKDEWRGIAVYVEHHNGNIHPVTYELIGKAREMASKIK
                     QPVYCVFVGKDIKDKCSNLISYGVDEVFVYDEDEFKDFRIEPYSKAIENFIDKIKPTI
                     VLVGGTTLGRSLAPRLAARFRTGLTADCTILDIQSNTDLDQIRPAFGGNIMAHINTPN
                     NRPQFATVRYKIFSAPEKIENTTGKITLCKVEKKELKSKIKVLSVKEKNKEVGLEEAE
                     VIVVASRAIKKQEDMEMIYKLADKLNAQVAGTRPVIEAGWIDAKKQIGLSGRTVKPKL
                     IITCGVSGAVQFVAGMQGADYIVAINKDDKAPILDVAHLALIGDIYDIIPKLIEKIEN
                     NKDNNQKYMASAAK"
     gene            19404..20795
                     /locus_tag="OE968_002319"
     CDS             19404..20795
                     /locus_tag="OE968_002319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HCP7219596.1"
                     /translation="MYKLIDKKDIDFLIDTCGEENVLVGSDINEDFSHDELGGIEKYP
                     EVLVNVLETEQVSKIMKYAYKNNIPVTPRGQGTGLVGAAVAINGGIMINLCKMNKILE
                     VDYENLTLTVEPGVLLMTIGQYVQDRDLFYPPDPGEKSATIAGNINTNAGGMRAVKYG
                     VTRDYVRGLEVVLPNGEIINVGGKVVKNSSGYSIKDLLVGSEGTLGIVTKAILKLLPL
                     PKKSISLLIPFPDLSMAIETVPKIIKSKSIPTAIEFMERDVILAAEEFLGKKFPDNTS
                     DAYLLLTFDGNSTEDIEKEYEKVANLCLENGALDVFISDTQERNDSIWSARGAFLEAI
                     KASTTQMDECDVVVPRDKIAEFIRYTHELQDKLKIRIKSFGHAGDGNLHIYILKDGMD
                     DNTWKIRLKETFDYMYKKSRELSGQVSGEHGIGYAKKEYLHESNSDAYMMLIKNIKLA
                     FDPKNILNPGKIY"
     gene            complement(21058..22338)
                     /locus_tag="OE968_002320"
     CDS             complement(21058..22338)
                     /locus_tag="OE968_002320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HCP7219597.1"
                     /translation="MNILGLIVEYNPFHNGHIYHLSKSIEKTNATHTVAIMSGNFLQR
                     GEPALFDKYTRAKIAVENGVDLVIELPTLFACQSAEIFSHGAITILNSLNCINSICFG
                     SEEGNTEILYNIAEILANEPNEFKLLLKKYLDDGLLFPTARANALFDYIHQDKKNNFI
                     QNYSKEQLSKTLNSSNNILGIEYIKNLIHLNSSIKPFTISRVQSEYNSEEIESDICSA
                     TAIRTSLKENTDLFHLKNVIPEKTYNILNEKIDNGFLPMFDDFFFDILKTIILRDMDT
                     LKEYFEVNEGIENRIYKDIFTSEFLHELQLAIKSKRYTLTKIKRTLNNILLGIKKSDM
                     QLIKNIDTIPYIRILAFNDKGREILKEIKNKSEIKIINKFSNISFSLDDTIFKTLISY
                     DIKATNIYNSIYYKNNKDLVKGPMDFYTHPIYVK"
BASE COUNT         8835 a         2521 c         3991 g         7311 t
ORIGIN      
        1 aaggttatat cgatatatta attgtttcta tattagaaaa gaaagattgt tatggatatg
       61 aaattgcaaa gcaagtaaga gaaagaagtg agtttgaatt aaaagaagga acaatgtatc
      121 ttgcacttaa aagaatggaa tctaaaaatt taattaaatc ttattatagc aatgaacaaa
      181 gttcaggtgg aagaagaaaa tattataatt taactaatga aggtaaagat tttttagaaa
      241 taaagaaaca agaatggaga tttattaaaa aggttatgaa tcaatttttg ggagaggtgg
      301 attaatttat gaaactaata gatgaatatt tagataaact atataaaaaa tgtgacaata
      361 aaagtactat agaattaaaa caggaaatga gatgccatct tatagaatct gcaaatgaat
      421 ttaaattaga aggattagat gaagaagaag catgtaaaaa agcaattgaa agatttgatg
      481 atggtgatga aatgcagtat gaattatgta atataataaa agaactatct ttatcattgg
      541 ataggcataa atcaattgta atggggttta aaaaagtatt aggttacata agtataattg
      601 catttttaat ttctggattt atgtggtatt acaataatag tttacaacat aatatgtata
      661 atttaggaaa agaacttgat ggagaaataa agcaattggc agaaagacat gatatgacaa
      721 agattggtga atataagtta gaacttgaaa aaatacttga taaagataag tatagtaaag
      781 tcaaagctct tagactatat gtaatagata tgaaagatgg aaacactaat ttaagttctt
      841 ctggattgaa tgctaatatg gtatatgaga gggaagcaga ttataataac ataagtaatt
      901 ttatacagca tttaggatat aatggaaaag attttttaga caagaatggg aatatagtaa
      961 atccagatat tttcttagaa tatttctttt attttgaatc ggagatgtta attccagtag
     1021 catttgcatt tggattatta tgtataatag cgtattttat attaagattt aaaatttctt
     1081 taataaaaaa taataattaa ataattcacc aaataatctt aatttgtaga gtaaataaga
     1141 tgtttcaaaa taaaatttga atcatcttat tttttattgt ttgttatact cttttctttt
     1201 atatttctcc atagtggatt gtatctatac ataatcacat attttgatat aattatactt
     1261 tccaaaaaat gtattgaata tacaaattat aatctgtata atgttgttag gggagaatgt
     1321 atgaagtgta tacaatttta attttaaatg tattattgac aattctcctc actctcgcca
     1381 ttaccaataa ttggaaaatt gacatacctg ttacagacca acatttttga atatattaat
     1441 tattatcatt ttattgtgat gatatcaaaa atgcaggttt gtgagttgga ttgtatacga
     1501 actatatagg aaatatagaa cagattttcc aagaaatcta aatattctat gaccacgtga
     1561 attgctatgc atacatgttg ataatccata ttttaaatct aaaatgaact taattaatgg
     1621 tagggaattg aaagtaaaat atattataaa ggagaatgct aatatgaaaa aaatcaggaa
     1681 attagctact aaactattga ttgcaatgat ggttttaacc tcatgtatga gtgtaacagt
     1741 ttatggtatg acagctaaag atgttactgc aaagacaccg aaaagttatg tagctggaac
     1801 caacagtata tatggtccaa agttatcaca agctcaactt aattcggtag cacaagcaac
     1861 agcagacttt atgaacaaga aaattacaaa gaacatgacc acagatgcta agattagggt
     1921 tgcttataat cacattaaaa acaacacaac atatgttaac tggaacgcag cagagggagc
     1981 caatactgct tatacattgg ttactaaaaa aggtgcttgt tctggaatgt gtaggagctt
     2041 gaaagcttta tgtgatgcta tgggaattga atgttattat gtacatagta caacaaatga
     2101 ccatcagtgg aatcttattc gttttgagga tggacgtttg tatcatgtag atattgatgc
     2161 caacaaatca gcaggagcag acatcatata caagagtctt actcacccat taccatttga
     2221 caagaaagca tatccagctg ttggcgaagt agtaaagaca cagaatccaa cgccaactgt
     2281 taagaaacct acgccagcta agccttctgc gccagttgga cctgggaatc acactatgat
     2341 agcagatcaa caaggggcaa tacttgatga agtttatgga aataatctac gtccaaaaat
     2401 tgaaatgtat gagggagttc cgtgtagttt aatcaactca tcaataaata caattaagtt
     2461 tacaagcaaa aattcaaatt tagacccatc aaagcataca gttactgtaa tagggtttat
     2521 gaatacacca tatggtatgg ttgcattagc tccagatggt gtacctgatg agtatccttt
     2581 tgaatatgat aagccatttt ctttagattt tactggtaag aacctttctg cagcagaatt
     2641 atcaaaaaag tgtaaagaaa ataatgtaat tattaaagtg gaaattggtg aaacggcatc
     2701 taattctgga agagggatgg tagcatacgc tagatatgtg aattaataca aatatactag
     2761 tgtacaaata gaacatatta taaataatgc accctcgcac aaagggtgca tttatcatta
     2821 tatcagtcat tttagaaaat aaaaaaggag ttgaacttaa aattagatta gaaaaattaa
     2881 ttttgagaca actccatttt aatttatttt taaatataaa atcatttatt ttaaataata
     2941 ttatgtttga ttaatggcta tttaactaat tttgcaaatt ctgcaccaaa tgccatacac
     3001 tcttttaatg tctcttcact agggaagaat tttttcttaa gagattctac aggcattttg
     3061 aatgacatag atttaagtaa agtctcagcc atagttatac cttcaccact ccaaccaaat
     3121 gaaccaaata ctcctgctat cttgccttgg ttagccattg ggtctataac agagaataaa
     3181 tcccacatag gtttaaccat agttttgttt atagttggag aacctagtaa tattactttt
     3241 gacactacta atgtatcgtg catttctgtt aatgtcatat cttctaaatc atataattca
     3301 gcctttgcac cttctttatc aagtccttct tttatctttt tagccatctc taaagtatta
     3361 ctataagctg ataagtagaa tatagaaact tgattttgat tagttgtatt aacagcttct
     3421 gtagaccact caacatatct tttaacagca gccattgggt ctttagtaag cattggacca
     3481 tgagaagtca atatagtatc aaattctatg tttagtccta ccaccttatc tacagcactt
     3541 aaaacatgtt tagcaaatgg cttaactata caatcatagt agtgtttagc tgattttaga
     3601 taatcttcac tattcactac ctctgcatca acacttgcaa agtgacaacc aaatgcatca
     3661 caagttaaaa gagtcttgtc ctcctcaatg taagtaaaca ttgtatcaac ccaatgtaag
     3721 aatggagcag ttataaatct aagatttctt ttaccgatat ttaaaatttc accatctttt
     3781 attacatgac agttaaaagg tctatttatt tgaccatcta agtatagttt agcagcttta
     3841 gtacaataaa cttctatatt aggatttata tctaataagt attttaaact acctgcatgg
     3901 tctggttctg tgtgatgaat tacaacatag tcaattttag ctatatcagt aacctctgat
     3961 aaattactta aaaactcatc tttaaaattt gcctttacag tgtcaaataa aaccgttttt
     4021 tcgtccttga ttaaataaga gttgtaagtt gtcccaaact cagtttccat tattatgtcg
     4081 aatactttta aaccttcatc tactactcca gtaaagtaga tatctttttt tacttcaaaa
     4141 actttactca tttttaaccc tcctaaaatt tatcattata taagtaacat accccatttt
     4201 gaggtgaatg aaacaaaaga tgtcatgata agtcatgtaa aacaatagtt ttatgtttat
     4261 aatatatcat actttgtaaa aaaattgtat ttcaataaaa atttaataga aaatattctt
     4321 aaatattttt agctattcta ttttgtgaat aatatgtatt ttaaattcaa tattttagtt
     4381 atatttttga tagaaaatat tttatcgtgt ataatattac ttataaataa gaataaaaat
     4441 aaagagcttg tttggaggaa ttttaataaa tgaataaagt agacttgaaa aaaatcttaa
     4501 aaaaagtaga aaagcctgct agatatcttg gaaatgaaat aaattcaatt cataaagata
     4561 ctagtaatag tgaattgata agatatgcac attgctttcc agatttatat gaagttggta
     4621 tgagtcactt agggagtcat atattatatg atgtaataaa taaggatgaa gatgtatttt
     4681 gtgagagagt gtattctcct gcagttgata tggaaaatat aatgagagaa aaaagtatac
     4741 cattatttgc attagagtca agagagccta taacaaactt tgattttgtc acttttacac
     4801 ttcaatatga actttcatac actaatatct taaatatatt agatttagcc aatataccaa
     4861 tattaaaaga agaaagaact ttggaagacc catttataat ggttggtggt ccttgtgctt
     4921 ataattccga accattagca gattttgtag atgtagtaat attaggtgaa ggtgaagagg
     4981 ttaatttaga agtagtaaat gagtataaag aatggaagaa aaataaaacg actagagaag
     5041 attttttata taaaatatct agcatagaag gagtatacat accaagtttt tatgatgtca
     5101 agtacaatga agatggtaca gttcaaagtg taactcctaa tagagaaggg attactaaaa
     5161 atcctactaa aaggataata aaagatgttg agactgtaga ttatccagaa aaactaatag
     5221 taccttatat agatactgtt catgatagaa tagtactaga attatttaga ggatgtacta
     5281 gaggatgtag attctgtcaa gcaggtatga tatacagacc aataagagaa aagagtgtta
     5341 aaagacttaa agaaatatta gataaattag ttaagaatac tggatatgat gaaatatcat
     5401 tatcatcact tagtacgagt gattatagta agttatcaga gttgactgat tatttggtag
     5461 atgaatatgc atctaataat attgggattt cgcttccatc ccttagatta gataattttt
     5521 caatggaaat tgctgataaa atacaacaag taagaaaatc tggacttact tttgctccag
     5581 aagcaggaac tcaaagactt agagatgtta taaataaagg tgttacagaa gaagatttgg
     5641 aaaatgcaac agaaagagct tttgagatgg ggtggaatag tgttaagttg tattttatga
     5701 ttggtttacc aactgagact tatgaagatt tagatggtat agctaaatta gcttataaag
     5761 ttattgatat ttatagaaaa gtaaatggag gaaagctaaa gagaagtttt agtgttacag
     5821 tgagtacttc tacatttgta ccaaagccat ttacaccttt ccaatggcat ggtcaagata
     5881 ctacagaaga agttattaat aagcagagac atttagtaaa taaattaaga aataacaata
     5941 taaaatacaa ttatcatgat tcaaagacta gtttgatgga agcagtagta gctagaggcg
     6001 atagaagaat aggaaaagtt atatatgatg catttagact aggtgctaaa tttgatggat
     6061 gggcagaaca ttttaattta gatatatgga aagaagctat ggaaaagaat aatctttcta
     6121 tagattttta tgcacataga aatagaaact atgaagaggt atttccttgg gaccatatag
     6181 atgtaggtat tagtaaaaaa ttcttaatta gagaagacga aaatgctaaa aaagaaaaaa
     6241 tcacttctga ttgtagacat aactgcaatg gttgtggaat aaatatacat gatataggaa
     6301 gggggctttg ctaatatgag taagataata agagtaaaat ttaaaaagga aggcgacatg
     6361 atatatatat cacatcttga ccttcagaga ttgttacaaa gagcgtttag aagagctgaa
     6421 ataaacttat cacattctca aggatttaat cctcacccta aaatgagtta tggcaatgct
     6481 ttggctttag ggacagaaag tcaaggtgag tatgtagata ttgaaataga agaagatgat
     6541 ttatcagtag aggaattttt aaataaagta tcaattcaac ttccagatgg gatagatttt
     6601 atcaaagcaa aagaaattga tagacaaaca ccttctcttt cttctgtgat agactatgga
     6661 gaatatttgt ttaatataga tttgaaaaga cctatgacga aagagtttgt aaaaagaaaa
     6721 gtaattgact ttatgaataa taaagaaata atcataacaa aaaagaataa aaaaggtaag
     6781 atggttgaag tagatataag acctatgata agaacctttg atgttttaaa tttagaagat
     6841 gaacatatta ctcttactgc tactatagct acaggctcaa aaactaattt aaatactaat
     6901 atacttatac caaagatatt agagatgttt gaacttgata ttgacccatt agatgttgat
     6961 atattgagaa gagatttata tgtattagaa gatggggaat tagtgactcc tatgtaagct
     7021 cgagaggtga agttgtgaaa aagatagtta ttgagtccct aatagggtcc cagaaaacag
     7081 cagtacttga agatgaaaga ttaacagaac tttttgttga agacaattta aataagaaga
     7141 ctgtatccaa tatatatcgt ggaatcgtaa aaaaagttat accaggaata gaagcttgtt
     7201 ttgtagatat tggatttaag aaacttgctt atttacaatt aaaaaaggga agtactataa
     7261 aatctggtca ggatattttg gttcagataa ataaagaaga aataggaact aaaggcgcaa
     7321 aattaaacac tgagattagt atttctggaa ggtatattgt ctatatacct tccaatgata
     7381 gaactacaat atcaaataaa attactgatg aaaaagaacg atttagatta aaaaaaatta
     7441 ctaaggcagt aaataaggaa aatctaggat taataataag gactgaggct caaggttgca
     7501 ctcatgatga aataaagaaa gatatagaag agttgaaatt aaagtatgaa aacattttaa
     7561 aagaatataa acttggtata ggtccgaaat tattatataa gtctttagat tttgcaacta
     7621 aatatgtaaa agataatgtg aatgatgata ttgaatctat aattaccaat agttatgata
     7681 agtactctga acttaagtct attttaagag gtatagataa gacttatgtt gataaactgt
     7741 gtcttgagga aaatagagat gtatttgatt tatacagaat agaatctaaa atagaaaaat
     7801 tattaaataa aaaagtatgg ttaaagagtg gaggttattt aataattgaa aaaacagaag
     7861 ctcttacggt tatagatgta aatacgggta agtttattgg aactggtaaa cttgatgaaa
     7921 ccgtttataa aactaatctt gaagctgcaa aagaaattgt aagacagctt agaattagag
     7981 acatagctgg gataataata atcgatttta ttgatatgca taaaaagaag catcaaaagg
     8041 agattttaca catcctagaa gaagaattta ataaagataa aagaaaagct gaagtattag
     8101 gtatgacaaa acttggttta gtagaagttg ctaggcgtag agaaaaagaa tccattgata
     8161 agtattattt aatgtcttgt ccatgttgtg atggtgaaca aacaataaaa tctgtacatt
     8221 atatactaga tagtattgaa aaagaaatta tgagaataag tgaacatact gtttacaaaa
     8281 acataatggt agaatttaat gattttattt ttgaacaaat aaaagaatat tatatggata
     8341 taattgataa aattggtgaa aaatataata taaagatttc tttaaacgca aatagtacat
     8401 taaagcacaa taaaaccaat gttattttcg ataaaatagt tgacaataaa atgtaaatat
     8461 tttataatta ataattgtaa tgccgcacag taaaggttta aatcttcaaa tgaagtacct
     8521 tgtactggcg agtttgaggc cgaggaggtg tatttaatgt acgctatagt aaagactggt
     8581 ggaaagcaat ataaagtttc tgaaggtgat gtattattcg ttgaaaaatt agaagctaac
     8641 gcaggtgatg ttgttacttt aaacgaagta ttagcttgct ctaaagatgg agaattaaaa
     8701 ttaggttctc cagtagtaga aggagcatct gttcaagcta aagttgttga acaaggtaaa
     8761 gctaagaaag ttatagtttt caagtataaa gcaaaaaaag attacagaag aaaacaagga
     8821 catcgtcaat catacactaa gatagttgta gaaaaaataa acgcttagtt attggttaag
     8881 ttatgataaa agttaaatat tattataatg atgatttctt gttgcaaggt ttttgtttaa
     8941 agggacatgc tgattttgct gaaataggct atgatatagt atgtgctgca gttacatcta
     9001 atgctattgc agttataaat tctttagaca aattacaaaa gattgaattt gaaaaagtag
     9061 taggagaaga aggtcatata gagtgtatag tcaaagatac acatgtaaaa gacgcacaat
     9121 tattactaaa tcactttcaa ttagcggtta aagaaattaa acgggaatac ccaaaaaata
     9181 taaaaatttt aaaaaagtag ggggtgactc catatgttaa acatgaattt acaattatta
     9241 gcatctaaaa aaggggtagg ttcttctaaa aatggtagag attctatatc taaaagatta
     9301 ggtgttaaga gattcgatgg tcaattagta actgctggaa gtataatagt tagacaaaga
     9361 ggaactaaaa tacatccagg aactaatgtt ggaaaaggta gtgatgatac tttatttgca
     9421 ttagttgatg gtactgttaa attcgaaaga aaagacaaga agagaaaaaa agttagtata
     9481 tatccagtag ctatagctga gtaatataca taaaaggagt gttgaggcac tcctttttct
     9541 tataatactg atgaatttat aatggtattt ttggtaatgc taattaaaag tttttaatta
     9601 agtaggtgaa gaatttgttt atagataagg caagaatatt tgttaaggct ggaaatggtg
     9661 gaaatggttc ggtagcattt agaagagaaa aatacgttcc agctggtggt ccagacggtg
     9721 gagatggtgg tcgtggagca agcatcatat ttgaagttga tttggggctt agaactctaa
     9781 tggactttaa gtaccagaaa aaatatcaag ctcaaaatgg tggcgacgga agcaaaggaa
     9841 aaagagctgg taaaaatgga gaaaatttag tattaaaagt accagcaggt acagtaataa
     9901 gagatgaggc tacaggtctt gtattagcag atttaaaaaa agaaggagat acagctatag
     9961 ttgcaaaagg tggtataggt ggtaaaggta accaacactt tgcaaatgca gtaagacaag
    10021 ctccagcttt tgcaaaatct ggtacagatg gagaagaaag atggataact cttgaactta
    10081 aaatgatagc agatgttggt cttttaggat ttccaaatgt aggtaaatca acatttctat
    10141 cagttgtaac taaagctaaa cccaaaattg caaactatca ttttacaaca cttacaccaa
    10201 atctaggtgt tgttcaaact aagtttggag atagttttgt acttgcagat atacctggaa
    10261 ttatagaggg tgcttctgaa ggcataggat taggtcatga gttcttaaga catgttgaga
    10321 gaacaaaggt attgatacat attgtagata tatctggatt agagggaaga gaccctattg
    10381 aagattttga caagataaat gatgagctta aattgtacaa tgaaaagctt tcaaagagac
    10441 cacaagttgt agttgcaaat aaatttgata tattagaaga tgagagtaag tttgagaagt
    10501 ttaagagtga attagaaggc agaggatata cagtatttaa aatgtcagca gcaactcgtc
    10561 aaggcataga tgaagtaata gcctatgttt ctaaaatgct aaaagaagta gaagatgtgg
    10621 agctagtttc agaagaagaa atgtatagac cagaacttga tattggtact gaagaagagt
    10681 taagtataga tattgaagat ggtgtgtatg tagttacagg taaagcactt agaagaataa
    10741 tgtattctgt aaattttgat gatatggaat cccttcaata tttccaaaaa gctatggaga
    10801 gtcaaggtgt ttttgatagg cttagagaaa tgggaataga agatggagat gtggttaaaa
    10861 tttatgaatt agaatttgag ttttacaatt aatttaaata tagattatag ataatttaag
    10921 tatagaatta tagaggtgag aatatgttaa aaggaaaaca aagggcgtat ttaagatctt
    10981 tggcaaatac tttaaagcct actacacaaa ttggtaaaga aggtgttaca gagagtttct
    11041 tagagcaatt agatggtatg ttaagaacta gagaattagt aaaagttact atattagaaa
    11101 atgcaggtct tgatactaaa gaaactgcta atgcagtatg tgaagcttta agagctgaat
    11161 ttgtgcaggc tattggtttt aaatttacta tttacaagag gaatattgaa gagcctaaaa
    11221 tactttttcc aggacatgaa caggcgaaag caaagactaa aaataataat gttacaaaaa
    11281 agggtaaacc aactaaaaga gctgttagat aatagtttat atccttttag ggaaataagt
    11341 taaaaaaata gtgacaattg gaagaaattg tattatacta ttaaacataa atttaaatta
    11401 gcaatcttat caagagtggc agagggactg gccctgtgaa gcccggcaac cagtatattt
    11461 aattatacat tggtgctaaa tcctgcagca tttatgctga aagatgagta taaacccgtc
    11521 atatggcttg agtttatact caagcttttt ttattggtat atttatatat ataaataatt
    11581 taatataatc aaaatgatgg gggtatgtta cagtgaagat agcaatatta gggtatggaa
    11641 cagtaggaag tggattaatt gatttaatag aaaataatac ttcaaaaaga gatatagaag
    11701 ttgttggaat tttagttaaa aataaagaaa aacacaagta taagaagtac tttgataaga
    11761 taactactga tatagaagat atatttgaca aggatattga tatactagtt gaagtaattg
    11821 gaggattaaa tccagctttt gattatgtaa caagagcgtt aaataaaaaa atacatgtag
    11881 tgacagctaa taaagattta ctggctgaaa aaggtagtga ccttatagaa ttagctaact
    11941 taaataatgt tagcatcaag tttgaagcat ctgtggcagg tggtattcca gttttaaaac
    12001 cattgataga atcactggaa ggcaacaata taaagagcat aaacgctatt ttaaatggga
    12061 cttgtaattt tatattatca aagatgtatg atgaaaattt accgtatgat gtcgctttaa
    12121 aacaggcaca agagttggga tttgcagaag ttaatccaga tgcagatgtt ttaggatatg
    12181 atagtgctag aaagttatct atattgtcta ctttatctta tggaaaaata gtatattgga
    12241 aagatttatt attagaagga ataacttcaa tagatgaaaa agatatagaa tatgcaaaaa
    12301 aattaaattg taagataaaa ttggttgcta gaagtaagta tgaatcagga gaagtaagtg
    12361 gatttgttag accagcatta gtggacaata ataatatgct ttcaaagata gataatgagt
    12421 tcaacgtagt tattttagta ggtgattcag taggtgaact ttcttttgta ggtaagggag
    12481 ctggaagagg tgcaacagga agtgctgttt atgcagatat tatagatata atagataata
    12541 gaagttcaaa tataaagtct ttttcaaaag ggaaattgga tttaagtgga cttatagaag
    12601 atgagtgtag tgcagtagtt agatttggtg ggtataataa taaagatgga attttagaat
    12661 gtttagataa atatgtagat agttatgata ttatagatga tgaagaattg gcgatttttg
    12721 taagtgcaaa gtcagaacat gagattgata gagttttgga aattgtaaaa agaaataatt
    12781 acagtgaatc agctaaaaaa ttattgaaga tagattaata tgtttatgca agaattatga
    12841 aaatttaata gggtgtctca aaatagagag ataagccttt tttccagtgt tgaaataata
    12901 aaaatatatt tgattttata aaaaaagagt gtcttatgaa ctaaaaagtt cattttgaga
    12961 cactcttttt taatatctgg tgaattaata agataataga aaaatgtata cgttataatt
    13021 aaccaataaa gaaattttca ctagcttcat taatagcttg ctgagttacc cttatatatc
    13081 gctgtgtagt ggctacagag ctgtgattta aaagttcttt aaccaactct aaattattgt
    13141 tactcttttc aaattgagta gtagcataga gctttctaaa gctatgtgta cttatattat
    13201 acagatttaa gtgtttacaa attatcctca actgtttttg aatagccttt gtctttatat
    13261 ttactaagta gtcatttgat ttaagattat actttcttgc atgttcattt atggactcaa
    13321 ttatattttt attaactggt ctatactgta atttgcccgt ctttttttca tttatttcca
    13381 acatattacc tttaaaatta cctatcttta atcttaaaat atctgatatt cttagaccta
    13441 aattagcttc taacattagt gccaatgcaa ctttaggatt ttttctaaat cttttttcaa
    13501 cgccattttc actataagta aagccagtat gtaatagttc cattatcttt ttatattcgt
    13561 ctatttctat aggtcttgtt gccattttca accactcctc ttagtttgat ttggtaagtt
    13621 taggtcggta tttattatat aatataaatg aaatattata taatggaaaa atttcccagt
    13681 aaacttatac aagtgtgata tatgtgatta aggagaattt tttgaaaaat atttctaata
    13741 aaattattaa attgtgatga aataactatg ctgttaaact aattaaaaag gttattaaaa
    13801 ttatgacaaa tataataaaa aaatggaagt atttagttaa gttttattag ttttattttt
    13861 agttttattt ttttcgtgaa aatttcttag tgaaaaaagt atttttatat cgcattagtt
    13921 tcccatttgt agataaagtt ttcatatgtt tttttgcaat aaatacggct gagattagat
    13981 aaattattac tacaatttga agaattgtat cataatagct aaggtaataa aaccagatta
    14041 aattattata tataacgttg tatgtatcag caaagctaga aaccaacaca gcagagtttg
    14101 caattggata aagtataaat ataaagatag cagctaaaac tccatgcgca aatttactta
    14161 gtatgtataa ttttaaatct atgtccgttt ttgatagaaa tgtacaacat tgagctagga
    14221 tggataatcc actaaatcct atcaaaaaac tagctaaaga tgctcttaaa atttctggag
    14281 aacttgttat actagatact ttattgcatc ctatagtaat ttcaaataga ccacttacaa
    14341 atgcttgaca gagttcttta ctaacaccta aaaatgaaag aggcaaatat ataactgatg
    14401 ctattaatga gattacatta aaaagagata gtattttaaa tactactgaa aaaacaatta
    14461 caaatccacc aactgtaagt aatgtgttta ctccattaaa tacagcattt ccaaataaaa
    14521 caaaaaaacc attcccactt gaatttctaa tgttgattac attttttata tttgttttta
    14581 aatccaattt tgtctttgga aggttttcat taccataatt tctaaagaaa agaccaacca
    14641 atatagttcc tagataatgg cagagaatca ttaaataacc taagtttgaa ttttggaaca
    14701 tacctgtacc aaccgaacct attatgaata aaggtcctga tgtagaacaa aaagacacaa
    14761 gtctttgtgc ttcatactta gaaatttgtc cattactcct aaattcagaa gctaaactta
    14821 ctcctactgg ataaccagat actgtagata tagcaaaagc taaagcgctc tttcctgaaa
    14881 cattaaatac aaatctagtt atgggattga tgataaaccc tataatatcc actattttta
    14941 aatcaacaat taagtttgct ccaattataa atggtagtag tgatggaact aaaacattag
    15001 accatataga aaagccttct cttgcagatt ttatagcttc atttgggtat aggataatcc
    15061 ctaaaactag aactccaact atgatagatg gagcaaaaaa agcaataatt ttattttttt
    15121 tcataatatc acctgtaaat ttgagttata agatattata ttaaaagtaa taaaaatata
    15181 tgaatgtaat ggcttaagat atataataga tatatattac aacaacgatt atcatattgg
    15241 aggaaaaaat gtttaatagt atagctagta aaaaagttta tgaacaagta attgagcaaa
    15301 tacaatataa aatactaaat ggagagttaa aaaaggggga taaattacta tcagaaagag
    15361 aactgtctga acaaatgaat gtgagtagaa cttccataag ggaagctatt agggtattag
    15421 agactatggg agtgatagaa agcagacagg gtgaaggaaa ttttatatgt acaaatatag
    15481 aaaaaacttt aatagaacct ttatctatga tttttaaact taataatggt acacttgaag
    15541 atatattaga gcttagaata atcctagaaa ttgagattgc aaaacttgct tcaaagagaa
    15601 taacttcttc tgaagttata gaattgaaac atataataga tgaaatgagg gtagaaacta
    15661 ataaaaaaga taataatcga gtactggtat tattagacca aaaatttcac agtaaactag
    15721 caacattaag taaaaattat ttaattcaaa gtctttttat gacagcatca aaattatttg
    15781 atggatttat agaagatgca agagaaaaaa taatcgcaga accttttaat gaaaatatat
    15841 tgcttaaaca gcatgaagct atatacaatg cagttgtaga aaatgatgta gaacttgcat
    15901 gtgagaaagc aaaggaacat atggatttta taagtaaaaa ttatagaaaa aatgaaaatt
    15961 aaaagtttgt tataaaataa attattcttg caaatggtag ataatggtac tattatataa
    16021 atgtaaaact ggtatgacca cataccaatt ttatagttta ttataatggg agattaaaaa
    16081 tggtaaagtt aaaagtaccg tattcaaaac aaggaatgat tttagaaata cctgatgaac
    16141 gttttctcgg tgttttggag tcaaaatcgg ataattatat agaacataag actcaagaag
    16201 agatagttga agaatctatg aataatccta taggctctaa ttctctggaa gaactggtta
    16261 aggggaaaaa gaatgtagtc ataattacaa gtgaccatac aagacctgta ccaagtagaa
    16321 taactatgcc aattatatta agaaggatta ggaatgttaa tccagaaatt gatgtgaaga
    16381 ttatagtggc aactggattt cataggccaa gtacaaggga agagctaatt tataaaatgg
    16441 gagaagaaat agtagataat gaagatatag ttatgcatat atctactgat gataaatcta
    16501 tgtgtaaagt agggatattg ccttcaggtg gagatttata tataaacaaa ctagcatatg
    16561 aggcagaact tttgatagca gaaggtttta tagaacctca tttctttgca ggtttttcag
    16621 gtggcagaaa aagcgtactt ccaggaatcg catctgcaaa gactataatg tacaatcact
    16681 gtagtgactt tatagatagt gataattcaa gaactggaaa attgaataat aatcctattc
    16741 atgaggatat ggtatatgca gctaaagttg caaaattagc attcatattg aatgttgtaa
    16801 tagataaaga taaaaaaata attgcttcct ttgctggtga tgtcgaaaaa gcacatacta
    16861 aaggatgtag atttgtaaca gagttatcaa aagtaaattc tataaaatct gatattgttg
    16921 taactacaaa tggtggatat ccactagacc aaaatattta tcaatctgtt aaaggaatga
    16981 cagcagctga agctacttgt aaagacggtg gagtaataat aatgatttca gcatgtaatg
    17041 atggtcatgg aggtcaatct ttttatgaaa atgtagcaaa tgcagattct ccaaaacaac
    17101 ttttagataa aattagaagt gtcgatagag tagatacgat tccagaccaa tgggaatttc
    17161 agatactagc gagaatatta tctaaatata ctgtgataat ggtaacagat aagtgtaatc
    17221 ctgaaatgat aaaaaaaatg catatgaaac atgcatttaa ctttaaagaa gctttagaaa
    17281 tggcgaatag tatagttggt aaggagagca aagtagtagt tatacctgat ggagtatcag
    17341 ttatagttaa ataaaaaagg agtgtacttt atggaaattt tgacatgtat taaacaagtt
    17401 cctggaacga cttcagtaga agttgatgaa actacaggag tactaaaaag agatggagta
    17461 gattcaaaaa tgaatcccta tgacctatat gctttagaaa cagctcttag aataaaggaa
    17521 gataagaaag cgaatctaaa agtacttagc atgggtcctc ctcaggcaaa gaaggtaatt
    17581 gaagaaagtt ttatgatggg agctgatgaa ggagcattaa taagtgatag gagatttgga
    17641 ggagcagatg tattggctac ttcctatacc atatcacaag gtattaagaa gatgggaaag
    17701 gtagacctaa taatttgtgg aaaacaaact actgatggtg atacagcaca ggtgggacct
    17761 gaagtagctg aatttttaga tatacctcat gttactaacg ttacaaaatt aattgaagtt
    17821 aaagatgaaa gtatagttgt tgaaatagat atgccaaatg atttacaagt atgtgagatt
    17881 gaatatccat gtttaataac tgtagaaaaa gacatttttc aaccaagact accttcattt
    17941 aaattaaaac ttaatactaa agatagagaa atacctgtat atagcttaga tgactttgaa
    18001 gataaaaatg aaaataacta tggacttaat ggttctccta ctcaagttgt aagaatattt
    18061 cctccaaagc caaatacaga taaaaatatt gtaagaggaa atgcagatga actaagtttt
    18121 gcacttgtaa ataaattaga ggaattaaag ttggtgtaag ggggagtaat aaatgtcaaa
    18181 gatagttgta aatcaagata aaataactga cttaaagaga attttagaaa tatgtccttt
    18241 tggggctata gaagaaaagt caggtatagt agaaataagt gctggctgta agatgtgcaa
    18301 gttgtgtgtc aaaagtggac caaaaggcgc atttgaattt atagagagta gtaaagtaca
    18361 aattaataaa gatgaatgga ggggaattgc agtatatgtt gaacatcata atggaaatat
    18421 acatcctgta acgtacgagc ttataggtaa agctcgtgag atggcatcaa aaataaaaca
    18481 acctgtgtat tgtgtatttg taggaaaaga cataaaagat aagtgcagta atttgatttc
    18541 ttatggggtg gatgaagtat ttgtatatga tgaagatgaa tttaaagatt ttaggataga
    18601 accatattca aaagcaatag aaaactttat agataaaata aaaccaacga tagtattagt
    18661 tggtggaact acattaggta ggtcattagc tccaagactt gccgctagat ttagaacagg
    18721 tcttacagca gattgtacaa tacttgatat tcaatcaaat actgatttag accaaataag
    18781 accagcattt ggtggaaata taatggctca tataaacaca cctaataata gaccacaatt
    18841 tgccactgta agatataaaa tattttcagc accagaaaaa atagagaata ctacaggaaa
    18901 gataacttta tgtaaagtag aaaaaaaaga actaaaatct aaaattaagg tactgagtgt
    18961 aaaagaaaaa aataaagaag ttggtctgga agaagctgaa gtgatagttg tggcaagtag
    19021 agcaataaaa aaacaagaag atatggagat gatatataaa ttagctgata agttaaacgc
    19081 tcaagtggca ggaacaagac ctgtaataga agcaggttgg atagatgcta aaaaacaaat
    19141 aggtcttagt ggtagaactg taaaacctaa attgataata acttgtggtg tatctggagc
    19201 tgttcaattt gttgcaggga tgcagggtgc tgactatata gtagcaataa ataaagatga
    19261 taaagcgcct atacttgatg tagcacattt agctttaata ggtgatattt atgatattat
    19321 tcctaaattg attgaaaaaa tagaaaataa caaagataat aatcaaaaat atatggcatc
    19381 agcagctaaa tagggggata gaaatgtata aattaatcga taaaaaagat atagattttt
    19441 taatagatac ttgtggagaa gaaaatgtat tagttggaag tgatataaat gaagattttt
    19501 cacatgatga acttggaggg attgagaagt accctgaagt tttagtaaat gtacttgaaa
    19561 ctgaacaagt atctaaaata atgaaatacg catataaaaa taatatacca gtcacaccaa
    19621 gaggtcaagg tactggtctt gtaggtgctg ctgttgccat aaatggtgga ataatgatta
    19681 atctatgtaa aatgaataaa atacttgaag ttgattatga aaatttaaca ttgacagtag
    19741 aaccaggtgt tttattgatg acaataggtc aatatgttca agatagagat ttattttacc
    19801 cacctgaccc aggtgaaaaa agtgctacaa ttgcaggtaa tataaacact aatgcaggtg
    19861 gtatgagagc agtaaaatat ggcgttacaa gggattatgt aagaggtctt gaagttgtac
    19921 taccaaatgg agaaattata aatgtaggtg gaaaggtggt taaaaatagt tctggatata
    19981 gtataaagga tttattagtg ggctcagaag gtactttagg aatagttact aaagctatat
    20041 taaaattgct tcctttacca aagaaaagta taagtttgct tataccattt ccagatttat
    20101 caatggcaat agaaactgtt cctaaaataa taaaatcaaa atcaatacca acggctatag
    20161 aatttatgga aagagatgtg atattggcag cagaagaatt tttaggtaaa aagtttccag
    20221 ataatacatc agatgcttat cttttgctta catttgatgg aaatagcact gaagatatag
    20281 aaaaagaata tgaaaaagta gctaatttat gtttagaaaa tggtgcatta gatgtattta
    20341 tatcagatac acaagaaaga aacgattcta tatggtcagc cagaggtgca tttttagaag
    20401 ctataaaggc atctacgaca caaatggatg aatgtgatgt cgttgttcca agagataaga
    20461 tagcagagtt tataagatac actcacgagc ttcaagacaa attaaaaata agaataaaaa
    20521 gttttggtca tgcaggagat ggaaatctac acatatatat tttaaaagat ggtatggatg
    20581 ataatacatg gaaaataaga ttaaaagaaa cttttgacta tatgtataaa aaatctagag
    20641 aacttagtgg tcaagtttct ggtgaacatg gcataggata tgctaaaaaa gagtacttac
    20701 atgaatcaaa ttcagatgct tatatgatgt taattaaaaa tataaagtta gcttttgacc
    20761 ctaaaaatat tttaaatcca gggaaaatat attagaaata ttaatttaat aatatttaca
    20821 aaacaaaaaa tattaaatta gatttaaata taatatttta aactttactt ttaaatctga
    20881 agctaaattg taaaattttt aggatggcaa tatttactta aatttagaaa gtaacataat
    20941 atttaagttg atgttgtcat cctaaaagca tgtgtacata aataaagtaa gactattgta
    21001 tcttatataa taaagagtta ataaaatgat ttttataaat atagttattt taaaaaacta
    21061 ctttacatat attggatgag tataaaaatc catagggcct tttactaaat ctttattgtt
    21121 tttataatat attgaattat atatatttgt agcttttata tcataactta tgagtgtttt
    21181 aaaaatcgta tcatctaatg aaaatgatat atttgaaaac ttgtttatta tttttatttc
    21241 agatttattt tttatctctt ttagaatttc tctaccttta tcattaaaag caagtattct
    21301 tatataaggt atagtatcta tgttttttat aagttgcatg tcgctttttt taatacctaa
    21361 caatatattg tttagagttc gtttgatttt ggttaaagtg tatcgcttgg atttaattgc
    21421 taattgtagt tcatgtagaa attcagatgt aaagatatct ttatagattc tgttttctat
    21481 gccttcattt acttcaaaat actcttttaa agtgtccata tctctaagta taattgtttt
    21541 taaaatatca aagaagaagt catcaaacat aggtaaaaaa ccattatcta ttttttcatt
    21601 taggatgtta taagtttttt ctggaataac attttttaaa tgaaaaaggt ctgtattttc
    21661 tttaagtgaa gttcttatag cagtagcaga acaaatatca ctctcaattt cttcggaatt
    21721 atactctgat tggaccctgg agatagtaaa tggttttata ctactgttta aatggatgag
    21781 gttttttatg tattctatac ccagtatgtt gtttgatgaa tttaatgttt ttgataattg
    21841 ttcctttgaa taattttgta taaaattatt ttttttgtct tgatgtatat aatcaaaaag
    21901 tgcattagct ctagctgttg gaaataacag accatcatct aaatattttt ttaaaagtaa
    21961 cttaaattca tttggttcat ttgctaaaat ttcagctata ttataaagaa tttctgtatt
    22021 tccttcttca ctaccaaaac atatagaatt tatgcagttt agtgaattta aaattgttat
    22081 agcaccatga gaaaaaattt cagcactttg acaagcaaat aaagttggta attctataac
    22141 taagtctaca ccattttcga cagcaatttt tgctctagtg tatttatcaa ataaagctgg
    22201 ttcgcctctt tgtagaaaat ttccactcat tattgctaca gtatgtgttg catttgtttt
    22261 ttctatagat ttagataaat gatatatgtg tccattatga aatgggttat attcaactat
    22321 taatccaagt atgttcataa aatactcctt ttatctttaa ttattttata tatatcacaa
    22381 tttattataa tatgtataaa atttaaattt ttaattataa aattaaaaaa cgtaaaaaaa
    22441 tttataaaaa tgtagaaatg ttacctacat aaaaaactgg ttaaatgtta ttaaaataac
    22501 tttattagct ctttatatta tattattata acaaatggga aagaataatc tacattaagt
    22561 taacttgtta atatattatt agtgaaatac acaatttacc atactagaaa tatgatataa
    22621 tataaaaaaa aagtatatac ttttatatta aaaggtga
//
LOCUS       DAJMZY010000063        22571 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.063, whole genome shotgun sequence.
ACCESSION   DAJMZY010000063 DAJMZY010000000
VERSION     DAJMZY010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 22571)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22571)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22571
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.063"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            149..1030
                     /locus_tag="OE968_002321"
     CDS             149..1030
                     /locus_tag="OE968_002321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HCP7219598.1"
                     /translation="MKKRLIIMILSVVLVLSSILTIFAYSNIKYNNNKLIYSNMIDKK
                     TQNSVKEILKENKINEKDIDTFIKAVNNYNKLQVKILQNNINISKSGYSSINAKQVPY
                     NLEKLQDNWVKKFPDYMDVNCRITAFRLFKDFINSNKKFTGDSIDLNVDLDTIMNNKD
                     AKFSIKDVEKFINFFSAIPAKDTDDTIKISEQIKNEWKKRKISFKNNKNISIINGFLR
                     YPETKNVFIGHTGICIKTKNGILFLEKYGVTSPYQVTKFKNKEDVKNYMFNRLKMSEG
                     EIELPDPIIMENDKLMK"
     gene            complement(1343..2122)
                     /gene="hisJ"
                     /locus_tag="OE968_002322"
     CDS             complement(1343..2122)
                     /gene="hisJ"
                     /locus_tag="OE968_002322"
                     /EC_number="3.1.3.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphatase HisJ"
                     /protein_id="HCP7219599.1"
                     /translation="MKDGHIHSPYCPHGSKDDFEKYVQRAMDVGITEMTFTEHFPYAN
                     GFRDPAPENDSCMSIEDLPKYFNDVKKLKEKYEGKIKINVGSEVDFIEGYEEGIKENL
                     NKYGKELEDSLLSVHIIKIDDDYYCVDYSVEEFQNLIDKLGSIEAVYNKYYETLIKAV
                     NSDLGIHKPKRIGHLNLVRKFNQVFPYDYKGNTILEELIKLIKEKGYELDYNVSGNRK
                     EYCKEPYIDGYLLELVKKYDIPLILGSDSHCAEEINKYDIV"
     gene            complement(2668..3018)
                     /locus_tag="OE968_002323"
     CDS             complement(2668..3018)
                     /locus_tag="OE968_002323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc transporter"
                     /protein_id="HCP7219600.1"
                     /translation="MIFDKEIVRYHHGHHDHDHCHEHTHGDICHEHPHDHAHDHDHEH
                     SHEESSESKDEKTLKILLVHWINHNETHEEGFREWVEKARAIGKEETAKSIEKAIEYM
                     EEANKMLLEAKKHM"
     gene            complement(3034..3450)
                     /locus_tag="OE968_002324"
     CDS             complement(3034..3450)
                     /locus_tag="OE968_002324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3842 family protein"
                     /protein_id="HCP7219601.1"
                     /translation="MIIAVIDGMGGGIGAQIVSSLREELPTYVEIYALGTNSIATSSM
                     MKAHANKGATGENAIVVSAKKANIIVAPISVIIPNSMMGEVTCNISEAIADSEALKIL
                     LPIMPENVELVGLEGKPLALLVKDSVNLIKKEFNIK"
     gene            complement(3469..3660)
                     /locus_tag="OE968_002325"
     CDS             complement(3469..3660)
                     /locus_tag="OE968_002325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CooT family nickel-binding protein"
                     /protein_id="HCP7219602.1"
                     /translation="MCESSAFICKSNNELEKVMENVVNIDPCDGKIYLTDLLGEQKII
                     DGIIKEIRLMDHKIIIQEN"
     gene            complement(3811..4626)
                     /locus_tag="OE968_002326"
     CDS             complement(3811..4626)
                     /locus_tag="OE968_002326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HCP7219603.1"
                     /translation="MNQWRVIHNKSYEGAMNMAIDEAIFTAYKKGHNKPTLRFYTWEP
                     ACLSIGYFQKLEDEIDLDKCRCMNIDYTRRITGGRAVLHDNELTYSIIIGEDNPLIDK
                     SINLSYRYISEGLVKGLNLSGIETDNLNRGERISRENLSAACFNAHASYEVTINNKKV
                     IGSAQSRKDGVLLQHGSIILDFDVEKLFKLIKTKTPELKERAMKFTAKKASGIENEIG
                     RKIDIDILQKNIVKGLAEQFNVEFVEGDLTDYEKQLVKELYEKYKNEEYNKKR"
     gene            complement(4673..5611)
                     /locus_tag="OE968_002327"
     CDS             complement(4673..5611)
                     /locus_tag="OE968_002327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HCP7219604.1"
                     /translation="MIRLSVGTAIELGILNKKSDIPPTTAYIMIGEKCINKCSFCSQS
                     IESSTRKDKLSRVIWPEFSKEEILDALKAYKGKNIKRICIQSMASEEAHNSVLDFINY
                     ISGKIDMPISLSAKLENDEQIKKFFSVGVDKIGIAIDAANKELYEKIKGNNYDEKLKF
                     ITEMSKSYPNKISTHIIVGMGESHEDIYNLYTYLKENDVTISLFAFTPVRGTKMEKIN
                     QPSIESYRRVQLMSYMINKGYPKEYFKFKNGYLNSIKLDNDILKDINKGYPFEIRGCK
                     DCNRPYYNERPGSTIYNYSRPLNQSEIDLAIREINL"
     gene            complement(5608..6480)
                     /locus_tag="OE968_002328"
     CDS             complement(5608..6480)
                     /locus_tag="OE968_002328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HCP7219605.1"
                     /translation="MNKNLSEKMEIAFDIKLKNFGNKIEFAYPNQTLALSTTSNQCSL
                     KCAHCNGHYLNNMVPIEEYEEKVQSRNITSFLLSGGCSYEGDVPINTHINTIKNLKEQ
                     GYRLNAHLGLMDKDSIVELCKYLDIVSFDLVFDDETIREVYKMKKSKEDYIEVYNTIQ
                     EHTEVAPHICIGLKGGQIKGEYEIIEYLQKNPPNKLTFIVLIPTKGTEYENVEPPELE
                     GVADILCEARINLPDTEINLGCMRPRGVYRKELDQLSIMCGVNRIVLPSRSAKNKAIE
                     MNMTINECKECCVL"
     gene            complement(6505..8433)
                     /locus_tag="OE968_002329"
     CDS             complement(6505..8433)
                     /locus_tag="OE968_002329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4445 domain-containing protein"
                     /protein_id="HCP7219606.1"
                     /translation="MIKVSFTPNNKEVYCNEGDILLEVARNADIFIDAPCNGNVSCGK
                     CKVKLLNGKVDTEKTRHITDDEWEQGYILACCTKVISDIEIEVPSKVSSSMHGMKIEG
                     SNKKEDREIFERAKKIIEEHNLQFKTNIKKKYIEMEEPNLDDNISDVDRLERYVRNNL
                     GYNEIDFRLDILRKMPTVFRKSDFKVTITYVQKQKKLTIINIEQGNKENSLYGVAIDI
                     GTTSVVVCLVDLYSKEVVDKASSGNAQIKYGADVINRIIYSTKKNGLETLHKAIVEET
                     INPLLKTIYERNGIDKEDVVTLVAAGNTTMTSLFLGVYTDFLRQEPYIPPFLKSPKLM
                     GENVGLFVNDSAYVYLAPSVASYVGGDITAGVLSAGIWSSEENVLFIDLGTNGEIVFG
                     NKDYMMSCACSAGPAFEGGGISCGMRASAGAIEKVIIDKETLEPTLKIIDECAPVGIC
                     GSGIIDLICQMITKGVIDRRGKIYRDLDNKRVRFNEHEIGEYVLAFKEEFDLENDIVV
                     NEVDIDNFIRAKGAIYSGAYTLVDSLGMDFSILDRVYIAGGIGNNLDIENSIIIGLLP
                     DIDREKFTYIGNSSLVGSYLALISKDAKNKLEEIGNQITYVELSVYPSYMDEFISACF
                     LPHTNIEQFPTAKKLLEE"
     gene            complement(8545..8922)
                     /gene="gcvH"
                     /locus_tag="OE968_002330"
     CDS             complement(8545..8922)
                     /gene="gcvH"
                     /locus_tag="OE968_002330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein GcvH"
                     /protein_id="HCP7219607.1"
                     /translation="MKLLPELKYSKDHEWVKVIDGDVVYIGITDYAQDQLGEILFVET
                     PEVEDTVTKGVDFGVVESSKVASDLISPVNGEVLEVNEKLEDEPECINEDPYENWILK
                     VKLADVAELDTLLSDKEYEAGLE"
     gene            complement(9009..11135)
                     /gene="cdhC"
                     /locus_tag="OE968_002331"
     CDS             complement(9009..11135)
                     /gene="cdhC"
                     /locus_tag="OE968_002331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CO dehydrogenase/CO-methylating acetyl-CoA
                     synthase complex subunit beta"
                     /protein_id="HCP7219608.1"
                     /translation="MNLYNIIFTGSEQALGAAQAMLAEAIEKNGKEHKVAFPDTAYSL
                     PCIYAATGQKMNTLGDLEGALEVVKSLINRTHLLEHAFNAGLATALAAEVIEALKYST
                     MDAPYSEPCAGHITDPIIRSLGVPLVTGDIPGVAVVLGECPDAESAAKVIKDYQSKGL
                     LTFLVGKVIDQAIEAGVKMGLELRVIPLGYDVTSVIHVVSVAVRAALIFGGLTPGDLN
                     GLLEYTANRVPAFVNAFGPLSELVVSAGAGAIALGFPVITDQTVLEVPMNLLTQKDYD
                     KIVATSLEARGIKIKVTEIPIPVSFAAAFEGERIRKSDMFAEFGGNRTEAWELVVKKE
                     ATEVEDHKIEIIGPNIDEVDADGVLRLPLAVIVKIAGKNMQEDFEPVLERRFHYFLNY
                     IEGVMHVGQRDMAWVRISKDAFDKGFRLEHIGEVLYAKMLDEFESVVDKCEITIITDA
                     EKVSELKGEAIAKYNARDERLASLVDESVDTFYSCNLCQSFAPAHVCVVTPERLGLCG
                     AVSWLDAKATKELDPTGPCQPIEKGECLDDRTGVWNSVNETVNQISQGAVESVTLYSI
                     LEDPMTSCGCFECICGIMPEANGFVVVNREFASVTPVGMTFGELASMTGGGVQTPGFM
                     GHGRHFISSKKFAYAEGGPERIVWMPKELKDYVADKLNATVKEMTGIENFCDMVCDET
                     IADDSEGVLAFLEEKGHPALAMESVM"
     gene            complement(11192..11998)
                     /locus_tag="OE968_002332"
     CDS             complement(11192..11998)
                     /locus_tag="OE968_002332"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HCP7219609.1"
                     /translation="MEKFMIIGERIHCISPSIRKALAERDPAPILKRAKEQLEAGAHY
                     IDFNIGPAERDGEEIMTWGIKLLQSEFNNVPIALDTANKKAIEAGLKVYDRTNAKPII
                     NSADAGSRFDLIDIAAEYEAMVIGLCAKEGIPRDNDERMAYCQEILEKGLMLGMEPTD
                     ILFDPLCLVIKGMQEKQVEVLEAIKMMTEMGLLTTGGLSNVSNGCPKHVRPVLDSAFL
                     AMAMANGFSSAIMNPCDPELMKTVKSCDIINGASLYADSFLELNEGGFAF"
     gene            complement(12048..13415)
                     /locus_tag="OE968_002333"
     CDS             complement(12048..13415)
                     /locus_tag="OE968_002333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA decarbonylase/synthase complex
                     subunit gamma"
                     /protein_id="HCP7219610.1"
                     /translation="MALKALDIFKLTPKKNCKDCGFPTCMAFSMKVASGAVEVGKCPH
                     MSDDAIAKLSEATAPLMKALKVGAGASEYELGGETVLFRHEKTLVSRNRYAVSFCTCM
                     SDEAVDAKIANMKKVDYVRIGEQMKVEMAVLEYCGDKDAYLKLIDKIKGSGLEVAYIL
                     ACDDAQVVKEAVEVLKDARPMVYGATKENYKDMIEVVKGASLPLGVKAGSLEELYETV
                     ELIQAAGYKELVLDVTGENIKDTYTNAIQVRRTALKEQDRTFGYPSIVFANRLSNSNP
                     MMEVALSSIFTIKYGSIIVIDDISYAKALPLFALRQNIYTDPQRPMRVEPKIYPINNP
                     DENSPVLVTVDFALTYFIVAGDIERSKVPVWLVIPDAGGYSVLTSWAAGKFGGNSISA
                     FIKESKVEEVTNCKDLIIPGKVAVLKGDIEDNLPGWNVVIGPEESMELPKFLKGYQEK
                     ACQTN"
     gene            complement(13446..14390)
                     /locus_tag="OE968_002334"
     CDS             complement(13446..14390)
                     /locus_tag="OE968_002334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA decarbonylase/synthase complex
                     subunit delta"
                     /protein_id="HCP7219611.1"
                     /translation="MAFKMSTQKYSGKISEVEVGIGEKAIKLGGENVLPFYSFDGEVG
                     NSPKIGIQISDVYPESWTDSYKELYKDVANCPVEWAKYVEANTQADFICLKFDGSDPN
                     GLDKSVDECADVAKAVIEAIKLPLVVAGSGNHEKDGKLFEKLAQTLDGHNCLFMSAVE
                     DNYKGVGASAGMAYAHKVGAESSVDINLAKQLNVLLTQLGVKGENIVMNVGCSAVGYG
                     YEYVASTMDRIRLAAFGQNDKTLQMPIITPVAFEVGHVKEAIAPIEDEPDWGCPEERT
                     IAMEVSTAASVLVGGSNAVILRHPKSIETIKELVNALA"
     gene            complement(14410..15180)
                     /locus_tag="OE968_002335"
     CDS             complement(14410..15180)
                     /locus_tag="OE968_002335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HCP7219612.1"
                     /translation="MGYNIAVAGKGGTGKTSLTGLLIDYLVKDKKGPVLVVDADANAN
                     INEVLGIEVEATIGEIREEVNQREKLGNAFPGGMTKAQYLQFRLNSIIEEGEGYDLLV
                     MGRSEGEGCYCFVNGILREQVNKISGHYKYLVMDNEAGMEHLSRKVTRHVDTLLLVSD
                     CSRRSIQAVARIRDLAEELKLSVGRILLIVNKVPNGVMNDGVKEEIEKHNLELIGVVP
                     MDELIYEYDSTGIPLVNLPEDSKSKVAMKEIFAKLELK"
     gene            complement(15236..16621)
                     /gene="lpdA"
                     /locus_tag="OE968_002336"
     CDS             complement(15236..16621)
                     /gene="lpdA"
                     /locus_tag="OE968_002336"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HCP7219613.1"
                     /translation="MKIVVVGGGPGGYVAAIKASMLGADVTVVEKRRVGGTCLNAGCI
                     PTKALLASSGVLNTVKEAKDFGIEIDGTVKPNFTAIMERKNKVVNQLISGIEFLFEKR
                     GVNLVNGFGKLIDKNTIEVTKDDGTVETIKADKIILANGSVPVVPRMFPYDGKVVITS
                     DEVLGLEEIPESMLIVGGGVIGCEIGQFFRALGTEVTIVEMVDQILLNEDKDVAKQLL
                     RQFKKDKIKVITGIGVQTCEVVDGKAVATLSNGKVIEAQYALVCVGRRPNLDNSGVED
                     IGIEMERGKVVVNEHLETNVEGIYAIGDIIDTPFLAHVASKEGIVAVENALGKTKVVD
                     YRAIPRCVYTEPEVAGVGKTEKQLEAEGVEYNVGQFDFRGLGKAQAIGHFQGFVKVIA
                     DKETDKIIGAAVVGPHATDLLTELSLAVHLGLTVEQVGDAIHPHPSLSEGLMEALHDV
                     HGECVHSVPKL"
     gene            complement(16665..17546)
                     /locus_tag="OE968_002337"
     CDS             complement(16665..17546)
                     /locus_tag="OE968_002337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase"
                     /protein_id="HCP7219614.1"
                     /translation="MSLLRETLESGKFAVTTEMAPPKGTDLSHLIECAKPLVGRVHAA
                     NVTDFQSAVMRATSLATCKLLKDAGLEPVIQITGRDRNRIAIQGEMLSAGVFGINNLL
                     ALTGDHTSVGDHPQAKGVFDLDSVGILQTAETLMAGTDMAGNKLKGSPDFYLGASVTP
                     EYSPIEVQLLKMKKKIKAGAKFFQTQALYDINTMRKFRELTRDMDCKVLAGIVPLKSP
                     GMAKFMTANVPGIFVPDEQIERLRAAGKENWVSEGIKMAGELIKQLKEEDLCDGVHIM
                     AIGAEENIPAILDAAGL"
     gene            complement(17582..18256)
                     /locus_tag="OE968_002338"
     CDS             complement(17582..18256)
                     /locus_tag="OE968_002338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase C-terminal
                     domain-containing protein"
                     /protein_id="HCP7219615.1"
                     /translation="MIISENKPLEEVLGYLKDFDKLVLVGCNQCAATCKSGGEEEVLK
                     MKETLEGEGKKILGYVMLDPACNLLKSKKDLKALKEETKEADAVLSLACGDGTQTIVK
                     NLKDKPVYPANNTLFIGEVQRVGEYEEACKACGDCELGWTGGICPVTMCAKGLMNGAC
                     GGAKNGKCEVNSENDCAWIKIYERLEAIGQLDNLAEIRPPKDYSKQNNPRSLSAKKKK
                     EAAANS"
     gene            complement(18293..19165)
                     /locus_tag="OE968_002339"
     CDS             complement(18293..19165)
                     /locus_tag="OE968_002339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 5,10-methylene-tetrahydrofolate
                     dehydrogenase/5,10-methylene-tetrahydrofolate
                     cyclohydrolase"
                     /protein_id="HCP7219616.1"
                     /translation="MEGMSTKGQIIKGKPVADKISEELIKEVDLLIKEGINPKLTIVR
                     VGARSDDLSYERGALKRCQNIGITTEVLELAEDITQEEYIDVLKRVNDDKNVNGILCF
                     RPLPKHLNEEVIKYVIAPEKDVDCFSPINSAKVMEGDKSGFPPCTPTAVVEILKHYNV
                     DLKGSKVTVLGRSMVVGKPVSMLLLSEHATVTICHSKTKNLSGVAAEADVLIAAIGRA
                     KMVDESFVKDGAVVIDVGINVDEEGNLCGDVDTNAVLDKVSMITPVPAGVGSVTTSIL
                     AKHVVKACKLQNNK"
     gene            complement(19257..19889)
                     /locus_tag="OE968_002340"
     CDS             complement(19257..19889)
                     /locus_tag="OE968_002340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclodeaminase/cyclohydrolase family protein"
                     /protein_id="HCP7219617.1"
                     /translation="MKIADKTCVDFVEVLSSKEAVPGGGGAAALVGAIGMALGSMVCN
                     LTIGKKKYAEYEESVKEILSKAGKLEKDLLKMIDDDAECFLPLSKAYGLPKETEEEKR
                     IKAETMEKALKVACEVPLNIVRVCYEAIKLHEDLVDKGSRLAISDVGVGVQCLRAAIL
                     GGQLNVVININSIQDKEYVNKVKTEVDKLVEDGVKICDEVYAKVEKALGK"
     gene            complement(19994..21670)
                     /locus_tag="OE968_002341"
     CDS             complement(19994..21670)
                     /locus_tag="OE968_002341"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014355320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HCP7219618.1"
                     /translation="MGFKSDIEIAQEAKPQDIREVAKKLGLGEDDVELYGKYKAKVDY
                     NLLKRETGKKAKLILTTAINPTPAGEGKTTTTIGVADAFAKLDKNVLVALREPSLGPV
                     FGVKGGAAGGGYAQVVPMEDINLHFTGDFHAIGAANNLLAAMLDNHIHQGNALRIDPK
                     KITWRRCVDMNDRQLRNIVDGMGKKGDGAVRQDGFDITVASEIMAAFCLASDISDLKE
                     RLGNIIVGYSYEGEPVTARQLKANGAMAALLKDALKPNLVQTLEGTPSFVHGGPFANI
                     AHGCNSVIATRMAMHFADYVITEAGFGADLGAEKFLDIKCRMANLKPDAVIIVATVRA
                     LKYNGGVAKADLNNENLEALEKGLPNLLKHVENITQVYGLPAVVAINRFPLDTEAELK
                     LVEDKCKELGVNVALSEVWAKGGEGGIAVAKEVLRLLDEEENNFRFCYEDDLSIKDKI
                     NAIATKIYGADGVDYTPEADKEIANLEKLGFTKVPVCMAKTQYSLTDDQTKLGRPTGF
                     RITVRQATISAGAGFIVALTGEIMKMPGLPKVPAAEKIDVDENGVIAGLF"
     gene            complement(21919..>22571)
                     /locus_tag="OE968_002342"
     CDS             complement(21919..>22571)
                     /locus_tag="OE968_002342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="carbon monoxide dehydrogenase"
                     /protein_id="HCP7219619.1"
                     /translation="LALGFPKEVYESIVPISEMKKLVSDRTAASVGSFGKMFKMNPKV
                     DDIPENFCKEYNGVRLLTLGTVDSGGTGCVCPEHVLLKRLCSHLILQNKDVVVMDMEA
                     GIEHLGRGTAQGVDAFIVVVEPGERSLQTYRKVKKLGHDIGVNKVFVVGNKIRNKEDE
                     EFIIQNLEDGESLGFIYYNQDVIDSDRANQSPYDSSETTKEQIKAIKDKLMSLKDK"
BASE COUNT         6816 a         4547 c         2548 g         8660 t
ORIGIN      
        1 tatatatatt tacatattaa aaaaaagttt taaataaagt tatatttttt acaacagttt
       61 tgtaattaaa aacatattga aggtaaattt aaaggtacta tatactataa atatgtcgac
      121 acaataaatt taaaaaggag aattaaatat gaaaaaaaga ttaataataa tgatattgtc
      181 tgttgtctta gtactatcaa gtatacttac gatatttgca tattcaaata ttaaatataa
      241 taataataaa ttgatatatt ctaatatgat agataaaaaa actcaaaata gtgtaaagga
      301 aatcctaaaa gaaaataaaa ttaatgaaaa agacatagat acatttatta aagcagtcaa
      361 caattataat aaattgcaag ttaaaatact tcaaaataat ataaatatat ctaaatctgg
      421 atattcttca atcaatgcaa aacaagttcc atataaccta gaaaaattgc aagataattg
      481 ggtgaaaaaa ttccctgatt atatggatgt aaattgtaga ataactgctt ttagactttt
      541 taaagatttt ataaattcaa ataagaaatt tactggagac tctattgatt tgaatgtcga
      601 cttggacact ataatgaata ataaagatgc taaatttagc atcaaagatg tagaaaaatt
      661 tatcaacttc ttttctgcaa taccagctaa agatacagat gatacaatca aaatttcaga
      721 acaaataaaa aatgaatgga aaaaaagaaa aatatctttt aaaaataata aaaatatatc
      781 tattataaat ggatttcttc gttatccaga aactaaaaac gtatttatag gtcatacagg
      841 catatgtatt aaaactaaaa atggcattct atttttagaa aaatacggtg ttacatcacc
      901 ttatcaagtt actaaattta aaaataaaga agatgtaaaa aattatatgt ttaatagatt
      961 gaagatgtca gaaggtgaaa ttgaattacc tgaccctata ataatggaaa acgataaact
     1021 tatgaaataa taactttaaa cgcaaaataa tatttataat tactaagtca atataataga
     1081 gaaggtctat agatttgtgt aaatacaagc ttatctacaa tcttatataa gaatatttat
     1141 ataaataaga tagattaatt ctaagtccta ttattctatt gaattttatt attattttat
     1201 ttagattcta ttgttatttt acttagaact tattattatt ttgtttaagt tctattacta
     1261 ttttcaatca tataaattta caaaagactg tacataaatt tattttatac aaacttatct
     1321 acagtctttt gtgtgaatat atctaaacaa tatcgtattt atttatttcc tctgcacagt
     1381 gagaatcaga acctaaaatt aatggaatat cgtatttttt taccaactct aataagtatc
     1441 catctatata aggctctttg cagtactctt ttctatttcc agaaacatta taatcaagtt
     1501 cataaccttt ttctttaatt aactttatta actcttcaag aattgtattt cctttataat
     1561 cgtatggaaa tacctgatta aactttctaa ctaaatttaa atgacctatt ctttttggtt
     1621 tatgtatacc taaatctgaa tttacagctt ttatcaatgt ttcataatac ttattataaa
     1681 cagcttcaat acttcctaat ttgtcgatta aattttgaaa ctcctctaca ctgtaatcta
     1741 cacaataata atcatcatca atcttaatta tatgtactga taaaagagaa tcctctaatt
     1801 cctttccata tttatttaaa ttctccttta tcccttcttc gtatccttct ataaaatcca
     1861 cttccgaccc aacatttatc ttgattttac cctcatactt ttctttcaac ttcttgacat
     1921 cattaaaata ctttggtaaa tcttcaatac tcatacaact atcattttca ggagcagggt
     1981 ctctaaatcc atttgcatac ggaaaatgtt ctgtaaatgt catttctgtt attccaacat
     2041 ccattgctct ttgtacatat ttttcaaaat catccttact tccatgagga caataaggtg
     2101 aatgtatatg accatctttc ataaataatt cactcctttt ttaaagaaaa aatctaatat
     2161 aaatgcataa atcttttaac ttcaaaataa tatttttaat catgctaatt tttattatat
     2221 ctaatattag agtaatttta aactgccttt taagtatctt atcattagta ctattttcaa
     2281 cttaacatta atattatttt ttaacttaac attaatacta tctttaaata gtaatactca
     2341 atatataatt acttaacata aaataactca aattgcttga tgaggctttt gcagtattta
     2401 aagaatatat aattatttaa cattaaataa tccaatcttg taataaaatt tactcattaa
     2461 agtatattac agaaaatacc tcaaaataaa ctttttagtt catgatatac tcttttttgc
     2521 atgaaattag atatattttt atcatttcaa caatgaaagg gaggcttata tccatcttta
     2581 gacaacccct tagataaaat ttttaataat taaacatcac aaaatataaa aatcgcttat
     2641 atcaaacgta taagcgatta attatattta catatgtttt ttagcctcta acaacatttt
     2701 attagcttct tccatatact ctatagcctt ttcaatactc tttgctgttt cttcttttcc
     2761 aatagctcta gccttttcaa cccactctct aaatccttct tcatgagttt cattgtgatt
     2821 tatccaatgt actaaaagta tttttaaagt tttttcatcc ttagactctg atgattcctc
     2881 atgactatgt tcgtggtcgt ggtcgtgagc atggtcatgt ggatgttcat gacatatatc
     2941 tccatgagta tgttcgtggc agtggtcatg gtcatgatgt ccatgatgat atcttacaat
     3001 ctctttatca aaaatcatta gttattcccc ctgttatttt atattaaact ctttttttat
     3061 aaggtttaca gaatctttta caagtagtgc taatggttta ccttctaatc caactaactc
     3121 cacattttct ggcataatag gtaaaagtat cttaagtgcc tcactgtctg caatagcttc
     3181 acttatatta caagtaactt ctcccatcat agaattaggt attattacag aaataggtgc
     3241 aactattata tttgcttttt tagctgatac tactatagca ttttcccctg tagctccttt
     3301 attagcatga gctttcatca tagaactagt tgctatagaa ttagtcccta gtgcataaat
     3361 ttctacatat gtaggtaact cttctctcaa agaagaaact atctgggctc caatacctcc
     3421 acccattcca tctatcactg ctattatcat atgaaattcc cctattaatt aattttcttg
     3481 tattattatc ttatggtcca tcaatcttat ttctttaatt atcccatcta ttatcttttg
     3541 ctctcctaat aaatccgtta aataaatctt tccatcacaa gggtctatat taaccacatt
     3601 ttccataacc ttttctaact cattattact tttacaaatg aaagctgatg attcacacat
     3661 ataaatctcc tcctaatatg atttttatta aaaatcaaaa aaagattccc ttaggtattt
     3721 caatacacca aagaaacctt catgatttca gtttttgtat attattatac cttaagtata
     3781 tcactttaat ttatgtaaag tcaattaaag ttaacgcttt ttattatact cttcattctt
     3841 gtatttttca tatagttctt taactaattg cttctcataa tcagtcaaat cgccctccac
     3901 aaactcaaca ttaaattgtt cagctaatcc ctttactatg tttttctgta gaatatctat
     3961 gtctattttt ctgccaattt cattttctat tccacttgct tttttagctg taaatttcat
     4021 agctctttct ttcaattctg gtgtcttagt ttttattaat ttaaacaatt tttctacatc
     4081 aaaatccagt attattgaac catgttgtaa taaaacacca tcttttctgc tttgagcact
     4141 tccaattacc ttcttattat taatagtaac ttcatatgat gcatgtgcat taaaacatgc
     4201 agctgataaa ttttccctac ttattctctc gcctctattt aaattatctg tttctatacc
     4261 acttagattc aaccctttaa ctagaccttc acttatatat ctataagata ggttgatgct
     4321 cttatcgatt aaaggattat cttctcctat aattatacta taagttagct cattatcatg
     4381 taatacagct cttccacctg taattcttct agtatagtct atattcatac atctacactt
     4441 atctaaatct atctcatctt ccaatttctg aaaatatcct atactcaaac aagctggttc
     4501 ccatgtataa aatctaagag ttggcttatt atgtcccttc ttatatgcag taaatatagc
     4561 ttcgtcaatt gccatattca ttgctccttc atatgattta ttatgtataa ctctccactg
     4621 attcatgatt attacgcccc catttttagt ataaatatat cctagaaatc ctctatagat
     4681 ttatttctct tattgctaaa tctatctcac tttgatttaa aggtcttgaa tagttgtata
     4741 tagtacttcc tggtctttca ttatagtatg gtctattaca atccttacaa cctcttattt
     4801 caaaaggata gcctttgttt atgtctttta aaatatcatt gtcaagcttt atactattta
     4861 agtatccatt tttaaactta aaatactctt ttggataacc tttatttatc atataagaca
     4921 ttaactgtac ccttctataa ctttctatgc ttggttgatt tatcttttcc attttagttc
     4981 ctctaactgg agtaaatgca aataaactaa tcgttacatc attttccttt aaataagtat
     5041 ataaattgta tatatcttca tgactttcac ccataccaac tattatatgt gtacttattt
     5101 tattgggata tgattttgac atttcagtta taaattttaa cttttcatca tagttatttc
     5161 cttttatttt ttcatatagt tctttatttg ctgcatctat tgctattcct attttatcaa
     5221 ctcctactga aaaaaacttc tttatctgtt catcattttc taattttgca gatagtgaaa
     5281 ttggcatgtc tatcttacca cttatatagt ttataaagtc taaaacagag ttatgtgctt
     5341 cttcacttgc cattgattga atacatattc tctttatatt ttttccttta taagctttta
     5401 aagcatctaa tatttcttct tttgaaaact ctggccaaat tactcttgat aatttatctt
     5461 ttctagtact actttctatt gattgagaac aaaaactgca tttatttatg catttttctc
     5521 caatcattat atatgctgtg gtaggaggta tatcgctttt tttgtttaat atcccaagtt
     5581 ctattgctgt cccaactgat agtctaatca taaaacgcaa cactccttac actcatttat
     5641 tgtcatattc atttctatag ccttattctt tgcagacctt gatggtaata ctattctatt
     5701 gactccacac attatagata attggtctag ctcttttcta tacactcctc ttggtctcat
     5761 acaacctaga ttaatttcag tatctggtaa attaattcta gcttcacata aaatatctgc
     5821 taccccttct aactcaggag gttctacatt ttcatactca gtcccttttg ttggaataag
     5881 gactataaat gtaagcttat taggaggatt tttttgtagg tattctataa tttcatattc
     5941 accctttatt tgtcctcctt ttaaaccaat acatatatgt ggtgctactt ctgtatgttc
     6001 ttgtattgta ttatagactt caatataatc ttctttactc tttttcatct tataaacttc
     6061 tcttattgtc tcatcatcaa acactaaatc aaaagaaact atatctaaat acttacacaa
     6121 ctctacaatg ctatctttat ccataagacc taaatgagca ttcaatctat atccttgctc
     6181 ttttaagttt ttaatggtat taatatgagt atttataggg acatctccct cataactaca
     6241 accgccactc aatagaaagc tagttatatt ccttgattgt actttttcct catattcttc
     6301 tattggcacc atattgttta agtagtgacc gttgcaatgg gcacatttca aactacattg
     6361 attgcttgta gtactaagag ctagtgtctg gttaggataa gcaaactcta ttttatttcc
     6421 aaaattcttt aatttaatat caaatgctat ttccattttt tcagatagat tcttattcat
     6481 agtttattcc ttcttaagta cattttactc ttctagtaat ttctttgctg ttgggaactg
     6541 ctctatattc gtatgtggta agaaacatgc agaaataaat tcatccatat aacttggata
     6601 tacactaagt tcaacataag ttatttgatt acctatttct tcaagtttat tttttgcatc
     6661 tttacttata agagctaagt aagaaccaac aagtgaacta ttccctatat aagtaaattt
     6721 ttctctatca atatcaggaa gtaaccctat aattattgag ttttctatgt ctaggttgtt
     6781 tcctatacca cctgctatat aaaccctatc taatatacta aaatccatac ctaaactatc
     6841 tacaagagtg tatgcgcctg aatatatagc tcctttagct ctgatgaaat tatctatatc
     6901 aacttcattg actactatat cattttctaa atcaaattct tctttaaatg ctaatacata
     6961 ctctcctatc tcatgctcat taaatctaac tctcttatta tctaaatccc tgtatatttt
     7021 acctcttcta tctattaccc ctttagtaat catttgacag attaaatcaa ttataccaga
     7081 accacatata ccaactggtg cacattcatc aataatcttt aatgttggct ctaaagtttc
     7141 tttatcaata attactttct ctattgctcc tgctgatgct ctcattccac agcttatccc
     7201 tccaccttca aaagcaggtc ctgctgaaca tgcacagctc atcatataat ctttatttcc
     7261 aaatacaatc tctccattag ttcctaaatc tataaataaa acattttctt cacttgacca
     7321 tatccctgct gataatacac ctgctgttat atctcctcct acataacttg caacagatgg
     7381 agctaagtac acatatgcac tgtcatttac aaaaagacca acattttcac ccataagttt
     7441 tggagatttt aaaaatggtg gtatgtaagg ttcttgtctt aagaagtctg tatacacacc
     7501 caagaataaa cttgtcatag ttgtattccc agcagccact aatgtaacta catcttcctt
     7561 atctattcca tttctttcat atattgtttt taatagtgga tttatagttt cctcaactat
     7621 agctttatga agtgtctcta atccattttt cttagttgaa tatataattc tatttataac
     7681 atctgctcca tattttatct gtgcatttcc agaagatgct ttatctacta cctcttttga
     7741 gtataggtct actaaacaaa caactactga agttgtacca atatctattg caactccgta
     7801 taaggaattt tctttatttc cttgttctat atttatgatt gtaagtttct tttgtttttg
     7861 aacatatgtt attgtaacct taaaatcact ctttctaaat acagttggca tttttctaag
     7921 tatatccaat ctaaaatcta tttcattata tcctaggtta tttctaacat atctttccaa
     7981 tctatctaca tcacttatat tatcatctaa atttggttct tccatttcta tgtatttctt
     8041 ttttatattt gttttaaatt gaaggttatg ttcttcaatt atttttttag ctctttcaaa
     8101 aatttcccta tcctcttttt tattactacc ttctatcttc ataccatgca tagaagatga
     8161 tactttagaa ggaacttcaa tttctatatc tgatattacc tttgtacaac aagctagtat
     8221 ataaccttgc tcccactcat catctgttat atgtcttgtt ttttctgtat caacttttcc
     8281 attcaataat tttactttac acttcccaca agacacgttt ccattacaag gagcatctat
     8341 gaatatatct gcatttcttg caacctctag taatatatcc ccctcattac aataaacctc
     8401 tttattgttt ggtgtaaaac ttacttttat catgttatcc ctcccaattt gttctatata
     8461 tgataaaagg aaagtatagc taaatttgcg tgcactcaaa ttttactata ctttccccaa
     8521 ttataataat atcttaatct ttaattattc taatccagcc tcgtattctt tatcacttaa
     8581 taacgtatca agttcagcca catcagctag ttttactttt aatatccagt tttcatatgg
     8641 gtcttcattt atacattctg gctcatcttc taatttttca ttaacttcca atacctcacc
     8701 attaacagga gatattaaat cagaagctac tttagaagac tcaactactc caaaatctac
     8761 tcccttagtt acagtatctt ctacttctgg tgtttcaaca aacaatattt ctcctaattg
     8821 atcttgagca tagtctgtta tacctatata tacaacatct ccatcaatta cttttaccca
     8881 ctcatgatct ttagagtatt ttaattctgg taataatttc atttcgatag acccccaata
     8941 ttatattatt gattaaatta cttaaatcat attaatatta tatcatatta ttttaaattt
     9001 tccatcaatt acattacact ttccatagct aatgctggat gacctttttc ttctaagaaa
     9061 gctaatactc cttcagaatc gtcagctata gtttcatcac aaaccatatc acagaagttt
     9121 tctattccag tcatttcttt aactgtagca tttaatttat cagctacata atcttttaat
     9181 tcttttggca tccaaactat tctttctggt ccaccttctg cataagcgaa ttttttagaa
     9241 gatatgaaat gtcttccgtg tcccataaat cctggagttt gaactcctcc acctgtcata
     9301 gaagcaagtt ctccgaaagt cataccaact ggagtaacac ttgcaaattc tctgttaact
     9361 acaacaaatc catttgcttc tggcattata ccacagatac attcgaagca tccacaagaa
     9421 gtcattgggt cttctagtat agagtataat gtaacagatt caactgcacc ttgagatatt
     9481 tggtttacag tttcatttac tgaattccat acacctgttc tatcatctaa gcactcgcct
     9541 ttttctattg gttgacaagg acctgttggg tctaattctt tagtagcctt agcatctaac
     9601 cagctaactg ctccacaaag accaagtctt tcaggagtaa caacacaaac gtgagctggt
     9661 gcaaatgatt gacataagtt acaagaatag aaagtatcaa cactttcatc aactaatgaa
     9721 gctaatcttt catctctagc attgtactta gctattgctt ctccttttaa ttcagaaact
     9781 ttttcagcat ctgtaattat agttatttca cacttatcaa ctactgattc aaattcatct
     9841 aacatcttag catataaaac ttctcctata tgctcaagtc taaatccttt atcaaatgca
     9901 tctttagaga ttcttaccca agccatatct ctttgtccaa cgtgcattac accttctata
     9961 tagtttaaga agtagtggaa acgtctttca agaactggct cgaaatcttc ttgcatattt
    10021 ttaccagcta ttttaactat tacagcaagt ggtaatctta atacaccatc tgcatcaact
    10081 tcatctatat ttggtcctat tatttctatc ttatggtctt caacttctgt tgcttctttc
    10141 ttaacaacaa gctcccaagc ttcagttctg tttccaccaa actcagcaaa catatcgctc
    10201 tttctaattc tctcaccttc aaatgctgct gcaaatgaaa ctgggatagg tatttcagta
    10261 acttttattt ttattcctct agcttctaat gaagtagcta ctatcttatc gtaatctttt
    10321 tgagttaata ggttcattgg aacttcaaga actgtttggt cagttataac tgggaatcct
    10381 aaagctattg ctccagcacc tgcagataca actaattcac ttaatggtcc aaatgcatta
    10441 acaaatgcag gaactctatt agctgtgtac tctaataatc cgtttaaatc accaggagtt
    10501 aatccaccga atattaatgc tgctcttact gcaacagata caacgtgtat aacagaagtt
    10561 acatcatatc ctagaggtat aactcttagc tcaagaccca tttttactcc agcttctata
    10621 gcttggtcta taactttacc aactaagaaa gttagtaaac ctttagattg gtaatctttt
    10681 ataacttttg ctgctgattc tgcatctgga cactcaccaa gaacaactgc aacaccaggt
    10741 atatctcctg taactaatgg tacaccaagt gatctgatta tagggtcagt tatatgacct
    10801 gcacatggct cactatatgg agcatccata gttgaatatt ttaatgcttc aattacttct
    10861 gctgctaaag ctgtagctaa accagcatta aaagcatgtt ctagtaaatg agttctattt
    10921 attaaagatt ttactacttc taaagcacct tctaagtccc ctaaagtgtt catcttttgt
    10981 cctgttgcag catatataca aggtaatgaa tatgctgtat cagggaaagc aactttatgc
    11041 tcttttccat tcttttctat agcttcagct aacatagctt gagccgcacc taaagcttgt
    11101 tctgaccctg taaagattat attatataga ttcattctat ttcccccttt aatatttaca
    11161 cctatttttt attaactata ccctaaaaac cctagaaagc aaatccacct tcatttaact
    11221 ctaagaaaga gtctgcatat aaagatgccc cgttgattat gtcacaagat tttacagttt
    11281 tcattaattc tgggtcacat ggattcatta tagctgaact aaatccatta gccattgcca
    11341 ttgctaagaa tgcactatct aaaacaggtc taacatgctt aggacatcca ttagatacgt
    11401 tagataatcc tcctgtagtt aaaagtccca tctcagtcat catttttata gcttctaaaa
    11461 cttctacttg tttttcttgc atacctttta taactaagca taatgggtca aatagtatat
    11521 cagttggctc cattcctaac attaagcctt tttctaatat ttcttggcag taagccatac
    11581 gctcatcatt atctcttggg ataccttctt ttgcacataa acctataacc attgcttcgt
    11641 attcagctgc tatatctatt aaatcaaatc ttgaaccagc atcagcagag tttattattg
    11701 gttttgcatt agttctatca taaactttaa gtccagcttc gatagctttt ttattagctg
    11761 tatctaatgc tataggaaca ttgttgaact cagattgaag taatttgatt ccccatgtca
    11821 ttatttcttc gccatctctt tcggcaggtc ctatattaaa atctatatag tgtgctcctg
    11881 cttctaattg ctcttttgct ctttttaaga ttggagctgg gtctctttct gctaatgctt
    11941 ttcttattga aggtgatata caatgtattc tctcacctat aatcataaat ttttccattt
    12001 ataatgtccc cctttaaatt taatattaat agttagttaa tattttatta gtttgtttgg
    12061 catgcttttt cttggtatcc ttttaagaac ttaggtaatt ccatagattc ctctggtcct
    12121 ataactacat tccatcctgg taagttatct tctatatcac ctttaagtac tgcaactttt
    12181 cctggaatga taaggtcttt acaattagtt acttcttcta ccttactttc tttaatgaaa
    12241 gcagagattg agtttccacc aaatttacca gcagcccaag atgtaagaac tgaatatcca
    12301 cctgcatctg gtattactaa ccatactgga acttttgatc tttctatatc accagcaact
    12361 atgaagtaag ttaatgcaaa gtcaacagta actaatactg gagaattttc atctgggttg
    12421 ttgattggat aaatctttgg ttcaactctc attggtcttt gtgggtcagt gtatatgttt
    12481 tgtcttagtg caaataatgg taatgcctta gcataactaa tatcatctat tactattata
    12541 gaaccgtatt ttatagtgaa tattgatgat aaagcaactt ccatcatagg gtttgaatta
    12601 gataatctat ttgcaaatac tattgaagga tatccaaatg ttctatcttg ctcttttaaa
    12661 gctgttcttc taacttgtat agcattagtg taagtatctt ttatgttttc tcctgttaca
    12721 tctaatacta attctttata tccagcagct tgaattaatt caactgtttc atataattct
    12781 tctaagctac cagcttttac acctaatggt aaacttgctc ctttaactac ttctatcata
    12841 tctttgtagt tctctttagt tgctccatat accattggtc tagcatcttt taatacttca
    12901 acagcttctt taactacttg tgcatcatca caagctaaaa tataagctac ttctaatcca
    12961 ctgcctttta ttttatctat taattttaaa tacgcatctt tatctccaca atactctaaa
    13021 acagccattt caactttcat ttgttcacca attcttacat agtcaacttt tttcatgtta
    13081 gctattttag catctactgc ttcatcactc atacaagtac agaatgaaac tgcatatcta
    13141 tttctactta ctaatgtttt ttcatgtcta aataatactg tttctccacc tagttcatac
    13201 tcagatgcac cagcaccaac ttttaaagct ttcattaaag gtgcagtagc ctctgataat
    13261 tttgctatag cgtcatcaga catatgtggg catttaccta cttctacagc tcctgaagca
    13321 accttcatag agaaagccat acaagttggg aatccacaat ccttacagtt tttctttggt
    13381 gttaatttaa atatatctaa agcttttaat gccattattt tttcccccta accttaacaa
    13441 tttaattaag ctaatgcgtt aaccaattct tttatagttt ctattgattt tggatgacga
    13501 agtataactg cgtttgaacc acctactaaa acacttgctg cagttgaaac ttccattgct
    13561 atagttcttt cttctggaca accccaatct ggctcatctt ctattggagc tatagcttct
    13621 ttaacatgac ctacttcaaa agctactggt gttatgatag gcatttgtaa tgtcttatca
    13681 ttttgaccaa atgctgcaag tctaattcta tccatagtag atgcaacgta ctcatatcca
    13741 taaccaactg ctgaacatcc aacattcata actatatttt cacctttaac gcctagttga
    13801 gttaacaata cgtttaattg tttagctagg tttatatcaa cagaagattc agctcctact
    13861 ttatgtgcat aagccatacc agctgatgct cctactcctt tgtagttatc ttctactgct
    13921 gacataaata agcagttatg tccatccaat gtttgagcta atttttcaaa taatttacca
    13981 tctttttcat gatttcctga accagctaca actaaaggta attttattgc ttcaattact
    14041 gccttagcta catcagcaca ttcatcaact gacttatcta atccatttgg gtcagaacca
    14101 tcaaatttta aacaaataaa atctgcttgt gtattagctt caacatattt agcccactct
    14161 actggacaat tagctacatc tttgtataat tccttatatg aatcagtcca gctttcagga
    14221 taaacatctg atatttgtat ccctattttt ggagaattac ctacttctcc atcaaaacta
    14281 taaaaaggta atacattttc cccacctaat ttaattgctt tttcccctat tcctacttca
    14341 acttctgata tttttccaga atatttttga gtagacattt taaatgccat atttttttcc
    14401 cccttaagcc tattttaatt ctaatttagc aaaaatttct ttcatagcca ctttagattt
    14461 tgaatcttca ggtaaattaa ctaaaggaat acctgtagaa tcatattcat atatcaattc
    14521 atccataggt acaacaccga ttagctctag gttatgcttt tcaatttctt ctttaacacc
    14581 atcattcata accccatttg gaactttatt tacaatcaaa agtattcttc caacacttaa
    14641 ctttagttcc tcagctaaat ctcttattct agcaacagct tgtatgctac gtcttgagca
    14701 atcactaacc aataaaagtg tatcaacatg tctagtgact tttctactta gatgttccat
    14761 accagcttcg ttgtccatga ctaagtattt gtaatgacca gatattttgt ttacttgttc
    14821 tctaagtatc ccatttacaa aacagtaaca tccttcacct tctgacctac ccattactaa
    14881 taagtcatat ccttcgcctt cttcgattat agaatttaat ctaaattgaa gatattgtgc
    14941 ctttgtcata ccaccaggga atgcattgcc taacttttct ctttgattta cttcttctct
    15001 tatttctcct attgttgctt caacttcgat acctaatact tcatttatgt tagcattggc
    15061 atcagcatct acaactaata ctggtccctt tttgtcctta accaaataat caatcaaaag
    15121 ccctgtgaga cttgttttac cagttccacc ttttcctgca acagctatat tgtatcccat
    15181 tttaagactt cccccttaaa tctagccaca gagccttatg tactctgtct gtctattata
    15241 atttaggtac agaatgaaca cattctccat gtacatcatg aagtgcttcc attagccctt
    15301 cagataaact tggatgtgga tgtattgcat cccctacttg ttctactgtt aatcctagat
    15361 gaacagcaag tgacaactct gtcaataaat ctgtagcatg aggtcctact actgctgcac
    15421 ctattatctt atcagtttct ttgtcagcta taacttttac aaatccttgg aaatgtccta
    15481 tagcttgtgc ttttccaaga cctctaaaat caaattgacc tacattgtat tctacacctt
    15541 cagcttcaag ttgcttttca gtcttaccaa caccagcaac ttcaggttca gtataaacac
    15601 atcttggaat tgctctataa tctactacct tagtcttacc taaagcattt tcaactgcta
    15661 cgataccttc tttagaagca acatgtgcta ggaaaggagt atctattata tcgcctattg
    15721 cgtatatacc ttctacatta gtttcaagat gttcattaac tactactttt cctctttcca
    15781 tttcaattcc tatatcttct actccagaat tgtcaaggtt aggtcttcta ccaacacata
    15841 ctaatgcata ttgtgcttct ataacctttc cattagaaag agttgcaaca gccttaccat
    15901 caactacttc acaagtttgt actccaatac ctgtaataac cttaatttta tctttcttaa
    15961 attgtctaag tagttgttta gctacatctt tgtcttcatt taatagtatt tggtcaacca
    16021 tctcaactat agttacttct gttcccaagg ctctaaagaa ctgccctatc tcacatccta
    16081 taactccacc acctactatt aacatagact caggtatctc ttcaagtcca agaacttcat
    16141 cactagttat tacaactttt ccatcatatg ggaacattct tggtacaact ggaacagaac
    16201 catttgctag tattatctta tctgctttta tagtttctac tgttccatca tctttagtta
    16261 cttctatagt gtttttatca attaattttc caaaaccatt aactaagttt actcctcttt
    16321 tttcaaataa gaactctata ccacttatta attggtttac aactttattt tttctttcca
    16381 ttatggcagt gaagtttggc ttaactgtac catctatttc tataccaaaa tcctttgctt
    16441 cttttacagt attcaatact cctgaagaag caagaagtgc tttagttggt atacatcctg
    16501 catttaagca agttcctcca actcttcttt tttcaacaac tgttacatct gcaccaagca
    16561 tagaagcttt tatagctgct acatatcctc ctggtccacc acctactact actatcttca
    16621 tctttaattc ccccaaacct aatataatct acaatcttgc aatactataa acctgcggca
    16681 tccagtatag caggtatatt ctcttctgcc ccaattgcca ttatatgaac accatcacat
    16741 aaatcttctt cttttaattg tttgataagt tcccctgcca tttttattcc ttcacttacc
    16801 cagttttctt ttccagctgc tcttaatctt tcgatttgtt catctggaac aaatattcct
    16861 ggtacatttg cagtcataaa tttagccatt cctggtgatt ttaaaggtac tattcctgct
    16921 aataccttgc aatccatatc ccttgttaat tctctaaact ttctcattgt atttatgtca
    16981 taaagtgctt gtgtttggaa aaatttagcc cctgctttta ttttcttttt catttttaat
    17041 aattgaactt ctattggaga atattctgga gttactgatg ctcccagata aaaatctgga
    17101 gaacctttta acttattacc agccatgtcc gtacctgcca ttaaagtctc agcagtttga
    17161 agtatcccca cagaatctaa atcaaacact cccttagctt gtggatggtc tcctacgcta
    17221 gtatggtctc ctgttagtgc caacagattg tttatcccaa atacacctgc tgacaacatt
    17281 tctccttgta tagctattct atttctatct ctccctgtta tttgaataac tggctctaat
    17341 ccagcatctt ttaataattt acatgtagca agagaagttg ctctcataac tgccgattga
    17401 aagtctgtta catttgctgc atgaactctt ccaactaacg gctttgcaca ttctattaaa
    17461 tgtgaaaggt cagtcccttt tggaggagcc atttcagtag taactgcaaa ttttccactt
    17521 tctaatgttt ctcttaataa gctcatctct aatccccctt ttaaccttct aaaaaaaact
    17581 tttatgaatt tgctgctgct tctttctttt tctttgcact taaacttctt ggattatttt
    17641 gcttagaata gtcttttggt ggtcttattt ctgctaagtt atctaattgt cctatagctt
    17701 ctagtctttc atatatcttt atccaagcac aatcattctc tgagtttact tcacacttac
    17761 catttttagc tccaccacaa gccccattca taagaccttt agcacacata gttactggac
    17821 atatcccacc tgtccaacca agttcacagt ctccacaagc cttacaggct tcttcatatt
    17881 ctccaactct ttgtacttcc cctataaaca aagtattgtt ggctggataa actggcttat
    17941 cttttaaatt cttaactatt gtctgtgtac catctccaca tgctaaagat aaaactgcat
    18001 cagcttcctt agtctcttcc tttagagcct ttaaatcctt tttagacttt aaaaggttac
    18061 aagcagggtc aagcattaca tatcctaaga tttttttgcc ttcaccttca agagtttcct
    18121 tcatttttaa aacttcttct tccccaccac ttttacaagt tgctgcacat tgattacaac
    18181 caactaaaac cagcttgtca aaatctttta agtaccctag cacttcttct aatggtttat
    18241 tttcagaaat tatcatatct acttcccccc taaaccttcc acatatatat atctatttat
    18301 tgttttgtaa tttacaagcc ttaactacat gttttgcaag tatagatgtt gtaactgaac
    18361 caacccccgc tggaactgga gttatcattg atactttgtc taaaactgca tttgtatcaa
    18421 catctccaca taaatttcct tcttcatcaa catttatacc aacgtctata actaccgctc
    18481 catctttaac aaaactttca tcaaccatct tagctctacc aatagctgct attagcacgt
    18541 ctgcctctgc tgctacacct gatagatttt tagtttttga atgacatatt gtaacagttg
    18601 catgttcact taataaaagc attgatactg gctttccaac taccattgat cttccaagaa
    18661 ctgttacctt acttcctttt aaatcaacat tatagtgttt taatatctca actactgctg
    18721 taggtgtaca tggtggaaat ccacttttat ccccttccat taccttagca gagtttattg
    18781 gactaaaaca atctacgtct ttttccggtg caataacata ttttataact tcttcattta
    18841 agtgttttgg aagaggtcta aaacataata taccattaac atttttgtca tcattaactc
    18901 tctttaatac atcaatatat tcctcttgtg ttatatcctc agctaactct aacacttctg
    18961 ttgttatacc tatgttttga catctcttta gtgctcctct ttcataagat aaatcatcac
    19021 ttcttgcccc aactctaact attgttagtt taggatttat accttcttta attagtaaat
    19081 cgacttcttt tattaattct tcactaatct tatcagctac aggttttcct tttataattt
    19141 gtcctttagt tgacattcct tccatacatt cacaactccc ctacaagcaa acttaaatta
    19201 atttattcta tataccacat attaataaca tagtatctac tttcgtcatt taaaaattat
    19261 tttccaagag ctttttcaac tttggcataa acttcatcac aaatttttac accatcttca
    19321 actaacttat ctacttctgt ttttacctta ttaacatatt ctttatcttg tatagaattt
    19381 atatttataa ctacatttaa ttgtccacca agtatagcag ctcttaaaca ctgaactcct
    19441 acaccaacat cacttatagc aagtcttgaa cctttatcaa ctaaatcttc atgtaactta
    19501 atagcttcat agcaaactct tactatgttt aatggtactt cacaagcaac ttttaatgcc
    19561 ttttccattg tttctgcttt tattcttttt tcttcttctg tttctttagg aagcccgtaa
    19621 gcttttgata atggtaagaa acattctgca tcatcatcta tcatttttaa taaatctttt
    19681 tctaactttc ctgccttact taatatctct tttacacttt cttcatactc agcatacttc
    19741 ttcttcccta ttgtaaggtt acataccata ctacctaaag ccatacctat tgcacctact
    19801 agtgcagcag ctcccccacc acctggtact gcttctttgg aagatagtac ttctacaaaa
    19861 tcaacacaag ttttatctgc tattttcatg ataatcctcc ttgaaaggat gtaggaaaat
    19921 atctcaaatt gttcgagata ttttacgaac tattttaaga tatctcctac tctttattta
    19981 taaattaatt tccttagaat aatccagcta ttactccatt ttcatcaaca tctatttttt
    20041 ctgctgctgg aacttttggt aatcctggca tcttcattat ttctccagta agtgcaacta
    20101 taaatccagc tcctgctgaa attgttgctt gtcttacagt tattctaaat cctgttggtc
    20161 tacctaattt agtttggtca tcagttaaag aatattgagt tttagccata catactggaa
    20221 ctttagtaaa tccaagtttt tctaagttag ctatttcctt atcagcttca ggagtataat
    20281 ctacaccatc tgctccataa atcttagtag ctatagcatt tatcttgtct tttatagata
    20341 aatcatcttc atagcagaat ctaaagttat tttcttcttc atccaataat cttaaaactt
    20401 ctttagctac tgcaattcca ccttctccac cttttgccca tacttcagaa agagcaacat
    20461 taacacctaa ttccttacac ttgtcttcaa caagtttaag ttcagcttca gtatcaagtg
    20521 ggaatctatt gattgcaaca actgctggta atccatatac ttgagttatg ttttcaacat
    20581 gttttaataa gtttggaagt cctttttcaa gagcttctag gttttcgtta tttaagtctg
    20641 ctttagcaac tccaccattg tattttaatg ctcttacagt agcaactatt ataacagcat
    20701 ctggttttaa gtttgccatt ctacatttta tatctaagaa tttttctgct ccaaggtcag
    20761 caccgaaacc agcctcagtt attacataat ctgcaaagtg catagccatt cttgtagcta
    20821 taacagagtt acatccatga gctatatttg cgaatggtcc accgtgtaca aatgatggtg
    20881 ttccttcaag agtttgaact aggtttggtt ttaaagcatc ttttaataat gcagccatag
    20941 caccattagc ttttaattgt ctagctgtta caggttcacc ttcgtagctg tatccaacta
    21001 ttatgtttcc taatctttct tttaaatcag atatatcact tgccaaacag aacgctgcca
    21061 ttatttcaga agcaacagtt atatcgaatc catcttgtct aactgctcca tcaccttttt
    21121 tacccatacc atcaacgata tttctaagtt gtctatcgtt catgtctaca catcttctcc
    21181 aagttatttt cttagggtct attctaagtg catttccttg gtgaatatgg ttatcaagca
    21241 tagcagctaa aagattgtta gcagctccta tagcgtgaaa atctcctgtg aagtgtaagt
    21301 ttatatcttc cataggaaca acttgtgcat atcctccacc agctgctcca cctttaacac
    21361 caaatactgg tcctagagat ggttctctta aagcaactaa tacatttttg tctagtttag
    21421 caaatgcatc agcaacacct atagtagtag tagtttttcc ttcacctgct ggagttgggt
    21481 ttatagctgt agttagtatt aacttagctt ttttaccagt ctctcttttt agtagattgt
    21541 agtcaacttt tgctttgtat ttaccataaa gttctacatc atcttcacct agtcctaatt
    21601 tttttgcaac ctctctaata tcttgaggct tagcttcttg agctatttca atgtcagatt
    21661 taaatcccat aactgaatct cctcccacaa cctaaataga tttaaaatat aatttttgta
    21721 aaaattgtat taatatgtaa aaattatatt ttataagata attatacatg taaaattact
    21781 taaaaactag ctactaagct attaaaatat tcaaacttaa tagctagtta tttatctaat
    21841 tacttactta ttacctatct attgcctatg tctaaccttt aaccaactta aaatcccaaa
    21901 tcaaaatttc tatctatttt acttatcctt aagtgacatt aatttatctt ttattgcttt
    21961 aatctgttct ttcgttgttt cactagaatc atatggagat tgattagctc tatcagaatc
    22021 aataacatct tggttataat aaataaatcc taaagattct ccatcttcta agttttggat
    22081 tataaattct tcatcttcct tatttctaat tttatttcct actacaaata ctttatttac
    22141 acctatatca tgtccaagtt tcttaacttt tctataagtc tgtagacttc tctctcctgg
    22201 ttctacaact actataaaag catctacacc ttgggctgtt cctcttccta agtgttcaat
    22261 tcccgcttcc atatccataa ccactacatc tttattttgt agtattaaat gtgagcagag
    22321 tctcttcaaa agaacatgct ctggacatac acatccagta ccaccagaat ctacggttcc
    22381 caatgtaagt aatcttactc cattgtattc tttacagaaa ttttcaggga tatcgtctac
    22441 tttaggattc atcttaaaca tttttccaaa tgaacctaca gaagcagctg ttctatctga
    22501 aactaatttt ttcatttctg atataggtac tattgattca tatacttctt ttggaaaacc
    22561 tagtgctaaa g
//
LOCUS       DAJMZY010000064        22313 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.064, whole genome shotgun sequence.
ACCESSION   DAJMZY010000064 DAJMZY010000000
VERSION     DAJMZY010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 22313)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22313)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22313
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.064"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            <1..369
                     /gene="tuf"
                     /locus_tag="OE968_002343"
     CDS             <1..369
                     /gene="tuf"
                     /locus_tag="OE968_002343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887863.1"
                     /note="EF-Tu; promotes GTP-dependent binding of
                     aminoacyl-tRNA to the A-site of ribosomes during protein
                     biosynthesis; when the tRNA anticodon matches the mRNA
                     codon, GTP hydrolysis results; the inactive EF-Tu-GDP
                     leaves the ribosome and release of GDP is promoted by
                     elongation factor Ts; many prokaryotes have two copies of
                     the gene encoding EF-Tu; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HCP7219620.1"
                     /translation="DNIGALLRGVQRNEIERGQVLAKTGSVKAHTKFTAEVYVLKKEE
                     GGRHTPFFDGYRPQFYFRTTDVTGACKLPEGIEMVMPGDNVTMEVDLINSIVVEEGLR
                     FSIREGGRTVASGVVATIIE"
     gene            741..1052
                     /gene="rpsJ"
                     /locus_tag="OE968_002344"
     CDS             741..1052
                     /gene="rpsJ"
                     /locus_tag="OE968_002344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HCP7219621.1"
                     /translation="MAKNEKIRIRLKSYDHKLLDFSAGKIVETAKKAGSQVSGPVPLP
                     TEKQVVTILRAVHKYKDSREQFEIRTHKRLIDIANPTPKTVDSLMRLDLPAGVDIEIK
                     L"
     gene            1144..1773
                     /gene="rplC"
                     /locus_tag="OE968_002345"
     CDS             1144..1773
                     /gene="rplC"
                     /locus_tag="OE968_002345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HCP7219622.1"
                     /translation="MKGILGKKVGMTQIFTDKGVVIPVTAVEAGPMVVTQIKTVDKDG
                     YNAIQIGFEDAKEKALNKPKKGHLAAANVLKKHLKEFRVDSVEGYTVGQEIKADVFEA
                     GAKIDVTGISKGKGFQGPIKRHGQSRGPETHGSRYHRRPGSMGACSYPGRVFKNKKLA
                     GHMGSVKVTVQNLEVVKVDADKNLILVKGAIPGAKGSVVTIKEAIKVSK"
     gene            1803..2426
                     /gene="rplD"
                     /locus_tag="OE968_002346"
     CDS             1803..2426
                     /gene="rplD"
                     /locus_tag="OE968_002346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001127258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HCP7219623.1"
                     /translation="MPKLNVLNVSGQNVGEIELSDSIFGVEVNGHVLYEVVKNQLANK
                     RQGTQSAKTRAEVRGGGRKPWKQKGTGRARQGSTRSVQWVGGGVAFAPKPRSYKYTLP
                     KKVRRLAMKSALSSKVQNSEVIVLDALNMDAPKTKEFAQILNNINAAKKALVVIADKN
                     DNVIKSARNIEGVQTALVNTMNVYDILKYDSFIITTDAVKKVEEVYA"
     gene            2426..2716
                     /gene="rplW"
                     /locus_tag="OE968_002347"
     CDS             2426..2716
                     /gene="rplW"
                     /locus_tag="OE968_002347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HCP7219624.1"
                     /translation="MTNPHDVIIRPVVTEHSMAEMGEKKYTFVVAKDANKTEIKKAVE
                     KVFGVSVDKVNTLNYDGKVKRMGRTQGRTSSFKKAVVKLTADSKEIEFFQGM"
     gene            2746..3576
                     /gene="rplB"
                     /locus_tag="OE968_002348"
     CDS             2746..3576
                     /gene="rplB"
                     /locus_tag="OE968_002348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HCP7219625.1"
                     /translation="MAIKKFRPTSPALRQMTVLVSDEITCNQPEKSLLVNLKKNAGRN
                     VHGRITVRHRGGGQKRKYRIIDFKRDKDGIPAKVATIEYDPNRTANIALLNYADGEKR
                     YILAPVGINVGDTILSGLGADIKPGNCLALKDMPVGTIIHNIELKPGKGAQLVRSAGV
                     SAQLMAKEGKNALLRLPSGEMRLVSINCKATIGQVGNIEHGNVVIGKAGRKRHMGIRP
                     TVRGSVMNPNDHPHGGGEGRSPIGRPSPVTPWGKPALGYKTRKKNKASNKLIVSRRTK
                     "
     gene            3611..3892
                     /gene="rpsS"
                     /locus_tag="OE968_002349"
     CDS             3611..3892
                     /gene="rpsS"
                     /locus_tag="OE968_002349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003454422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HCP7219626.1"
                     /translation="MSRSTKKGPFVHARLLKKIEAMNASGNKEVIKTWSRSSTVFPQM
                     VENTIAVHDGRKHVPVYITEDMVGHKLGEFVPTRTFKGHKDDEKSNKRK"
     gene            3924..4259
                     /gene="rplV"
                     /locus_tag="OE968_002350"
     CDS             3924..4259
                     /gene="rplV"
                     /locus_tag="OE968_002350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HCP7219627.1"
                     /translation="MEAKATAKYVRVSPRKAGQICDLVRGKNVDEALAILKFTPRGAA
                     SIIAKVVKSAKANAENNHEMDTEKLYIASIVANQGPTMKRFMPRAMGRATTIRKRTSH
                     IEVVVKEKK"
     gene            4282..5097
                     /gene="rpsC"
                     /locus_tag="OE968_002351"
     CDS             4282..5097
                     /gene="rpsC"
                     /locus_tag="OE968_002351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HCP7219628.1"
                     /translation="MGQKVNPHGLRVGVIKDWDSRWFATDKKEFGNLLLEDHNIRKFL
                     KKRLYSAGVAKIEIERSANKIKMDLHVAKPGVVIGRAGAGIEALKAELEKMTKKTIIV
                     NIVEVRSTDKNAQLVAENIALAIERRVAFRRAMKQAIQRAMKSGAKGIKVSASGRLGG
                     AEMARTEGYSEGNVPLQTLRADIDYGFAEADTTYGKIGIKVWICNGEVLPTRDGVNPR
                     EESRKSDRRDNKRDNRRNDRRGNDRRGNDNRGNYRGQRPQGGSRPQRTENKGN"
     gene            5133..5564
                     /gene="rplP"
                     /locus_tag="OE968_002352"
     CDS             5133..5564
                     /gene="rplP"
                     /locus_tag="OE968_002352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HCP7219629.1"
                     /translation="MLMPKRVKRRRVHRGSMAGQAHKGNKVTYGEFGLVALEASWITS
                     NQIEAARIAMTRYIKRGGKVWIKIFPHKPVTRKPAETRMGAGKGSPEYWVAVVKPGRV
                     MFELAGVSEDKAREAMRLAAHKLPIKCKFVKKEDLEVKGGE"
     gene            5566..5769
                     /gene="rpmC"
                     /locus_tag="OE968_002353"
     CDS             5566..5769
                     /gene="rpmC"
                     /locus_tag="OE968_002353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005810148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HCP7219630.1"
                     /translation="MKAKELRDLTSEELMNKLNDFKSELFSLRFQLATGQLENTARIK
                     FVKKDIAKVKTVLAERKLYETRA"
     gene            5793..6047
                     /gene="rpsQ"
                     /locus_tag="OE968_002354"
     CDS             5793..6047
                     /gene="rpsQ"
                     /locus_tag="OE968_002354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HCP7219631.1"
                     /translation="MERGRRKVRIGRVVSDKMDKTIVVAVEEFVRHPLYNKRVKRTKK
                     FKAHDEKNICNIGDRVKIMETRPLSKDKRFRLVEVVEKVK"
     gene            6073..6441
                     /gene="rplN"
                     /locus_tag="OE968_002355"
     CDS             6073..6441
                     /gene="rplN"
                     /locus_tag="OE968_002355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007885948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HCP7219632.1"
                     /translation="MIQQESRLRVADNSGAKELLCIRVLGGSKRRYGNIGDVIVATVK
                     SATPGGVVKKGKVVKAVIVRSKQGVRRNDGSYISFDENAAVIIKDDKTPVGTRIFGPV
                     ARELRDNEFMKIVSLAPEVL"
     gene            6465..6770
                     /gene="rplX"
                     /locus_tag="OE968_002356"
     CDS             6465..6770
                     /gene="rplX"
                     /locus_tag="OE968_002356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HCP7219633.1"
                     /translation="MRVKKGDTVVVIAGKDKGKKGSVLKVYPKTSKVLVEGVNVITKH
                     QKPSAMNQQGGIINKEAPIHISNVMPFDPETGKGVRVRYEVKDGNKVRVSAKSGKEL"
     gene            6800..7342
                     /gene="rplE"
                     /locus_tag="OE968_002357"
     CDS             6800..7342
                     /gene="rplE"
                     /locus_tag="OE968_002357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HCP7219634.1"
                     /translation="MASRLQEKYMKEVAPALMEKFGYKNVMEIPKLNKIVINMGIGDA
                     RENPKGLEKGVEELEMISGQKPVITKARKSVANFKLREGMPIGTKVTLRADKMFYFMD
                     KLVSVSLPRVRDFRGVNPNAFDGRGNYALGVKEQLIFPEIEYDKIDKVRGMDIIFVTT
                     AKTDEEARELLKLLGMPFSK"
     gene            7360..7545
                     /locus_tag="OE968_002358"
     CDS             7360..7545
                     /locus_tag="OE968_002358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HCP7219635.1"
                     /translation="MARKAMVVKQQRKQKYATREYTRCTICGRPHSVLKKFGICRICF
                     RELAYKGQIPGVRKASW"
     gene            7578..7976
                     /gene="rpsH"
                     /locus_tag="OE968_002359"
     CDS             7578..7976
                     /gene="rpsH"
                     /locus_tag="OE968_002359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012158382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HCP7219636.1"
                     /translation="MTMTDPIADMLTRIRNANVVKHETVDVPASNMKKELARILLEEG
                     FIRGYDVIEDGKQGIIRIQLKYGQEGERVITGLKKISKPGMRVYAANHEIPKVLNGLG
                     ISVISTSKGILTDKQARKENVGGEVICYVW"
     gene            8007..8549
                     /gene="rplF"
                     /locus_tag="OE968_002360"
     CDS             8007..8549
                     /gene="rplF"
                     /locus_tag="OE968_002360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HCP7219637.1"
                     /translation="MSRIGVKPIIIPAGVEVTIAEGNLVTVKGPKGTLTKQLSAELNI
                     KKEENTIMVERPTDNKKHRSLHGLTRTLLDNMVVGVNTGFEKKLELKGVGYRAQKQGK
                     KLVMNLGFSHPVEMEDPEGITVEAPNQTELIVKGIDKQLVGNYAAKIRAWRKPEPYKG
                     KGIKYVDEVIRRKEGKTGKK"
     gene            8585..8953
                     /gene="rplR"
                     /locus_tag="OE968_002361"
     CDS             8585..8953
                     /gene="rplR"
                     /locus_tag="OE968_002361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HCP7219638.1"
                     /translation="MLKKADKNANRLQRHKRVRRKISGTSQRPRLCVFRSANNIYAQI
                     IDDTKRVTLVAASSLEAEVKSAVNHTGNKEAAKKVGELVAKKAVEKGITEVVFDRGGY
                     LYHGRIQELAEGAREAGLKF"
     gene            8974..9483
                     /gene="rpsE"
                     /locus_tag="OE968_002362"
     CDS             8974..9483
                     /gene="rpsE"
                     /locus_tag="OE968_002362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011109776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HCP7219639.1"
                     /translation="MLRRKPIDAGQLDLQEKVVEVRRVTKVVKGGRNFRFAALVVVGD
                     ENGHVGIGAGKAMEVPDAIKKAVEDAKKNLIVVPIVGTTIPHEVRGHFGAGNILIMPA
                     VEGTGVIAGGPARAVLELAGLKDVRAKSLGSNNPRNMVNATIEGLNSLKTVEDIAKLR
                     GKKVEELLG"
     gene            9498..9683
                     /gene="rpmD"
                     /locus_tag="OE968_002363"
     CDS             9498..9683
                     /gene="rpmD"
                     /locus_tag="OE968_002363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HCP7219640.1"
                     /translation="MAKLQIKLVRSVIGTTPNQKKNVEALGLRKREQVVVKEDNAQTR
                     GMINKVSHLLEVTEIAE"
     gene            9716..10159
                     /gene="rplO"
                     /locus_tag="OE968_002364"
     CDS             9716..10159
                     /gene="rplO"
                     /locus_tag="OE968_002364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HCP7219641.1"
                     /translation="MKLHELKPAEGAVRAKRRLGRGTATGQGKTAGRGQKGQWSRSGG
                     GVRVGFEGGQMPLARRLPKRGFNNIFKKVYTEVNVEVLNRFENGTEITAELLKSTKTI
                     SKIGKDGIKILGEGNLEKALTVKAAKFTASAQEKIEKAGGKAELV"
     gene            10203..11471
                     /gene="secY"
                     /locus_tag="OE968_002365"
     CDS             10203..11471
                     /gene="secY"
                     /locus_tag="OE968_002365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HCP7219642.1"
                     /translation="MLSKLKQAWKIKAVRKKVMYTLMMIVIFRIGTTIPVPGIDTSII
                     QKMVGGNSLLSLYNMFTGGAFSNFSLFALGISPYITASIIIQLLTVGFESLAELQKSG
                     EEGKKKINKYTKYTALALAVVQALGITLGIVRSALISNSVFFITTVVITLVSASMLVM
                     WIGDKITEKGIGNGSSVIIFAGIISRIPTDVIKISQQVKSGEVAPWVIVILAVVILLT
                     VTGVTFIQEATRKIPVQYAKRVVGRKMYGGQSSHIPMKVNQSGVMPIIFASSLLAFPQ
                     TIAMFMGPNAQAFVQKYLSMATEQGFWTYRSIEILLIIFFSYFYTTVSFNTEDISKNM
                     KNNGGFIPGIRPGEPTMDYLNRILTRLTLAGATFLAIIAMVPALTTHYMKVNMSLAGT
                     SLLIVVGVALELKRQLESNLVMRSYQGFLK"
     gene            11488..12138
                     /locus_tag="OE968_002366"
     CDS             11488..12138
                     /locus_tag="OE968_002366"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HCP7219643.1"
                     /translation="MRIILLGPPGAGKGTQAAGIVEKYNIPHISTGDIFRKNIKEGTE
                     LGKKAKEYMDQGLLVPDELTVGLVTDRISQEDCKNGFMLDGFPRNVAQGEHLDIFLKN
                     AGISLDKVVNIEVDKSILVSRAVGRRICKSCGATYHVEFNPPKVEGVCDVCQGELYQR
                     ADDNEETVSKRIQVYLDETKPLVDYYSKQGIIADIKGDQAIDKVFEDIVAALGSGK"
     gene            12139..12885
                     /gene="map"
                     /locus_tag="OE968_002367"
     CDS             12139..12885
                     /gene="map"
                     /locus_tag="OE968_002367"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HCP7219644.1"
                     /translation="MIILKSKKEIELLREAGKIVADTHEVLRKAISPGISTLELDKIA
                     EENIRKYNAEPSFKGYGGFPGSICASINREVVHGIPGETILQEGDIVSLDIGAYYKGY
                     HGDSAKTHGVGMISEEDRKLIEVTRESFYEGIKFAKLGYRLSDISHAVQTHVEKHGFS
                     VVRDLVGHGVGANLHEDPQVPNYGLPGKGPRLREGMVIAIEPMVNAGRYHVKTLSDGW
                     TTVTIDGKKSAHYEHTIAITEHEPLILTKL"
     gene            12907..13176
                     /locus_tag="OE968_002368"
     CDS             12907..13176
                     /locus_tag="OE968_002368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KOW domain-containing protein"
                     /protein_id="HCP7219645.1"
                     /translation="MLSDNLSIGQVVKVSLGRDKGNLFFVVKIINNEYVLIADGKKRK
                     LDKPKLKKVKHLKKYNFINDEVRKRVVSGQEITDSFLRAELTKLN"
     gene            13214..13432
                     /gene="infA"
                     /locus_tag="OE968_002369"
     CDS             13214..13432
                     /gene="infA"
                     /locus_tag="OE968_002369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001029884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HCP7219646.1"
                     /translation="MAKKDVIELEGTVSEALPNAMFKVKLENGHEILCHISGKLRMNF
                     IRILEGDKVNVELSPYDLTRGRITWRKK"
     gene            13468..13581
                     /gene="rpmJ"
                     /locus_tag="OE968_002370"
     CDS             13468..13581
                     /gene="rpmJ"
                     /locus_tag="OE968_002370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HCP7219647.1"
                     /translation="MKVRPSVKPICEKCKVIKRKGKVMVICENPKHKQKQG"
     gene            13734..14105
                     /gene="rpsM"
                     /locus_tag="OE968_002371"
     CDS             13734..14105
                     /gene="rpsM"
                     /locus_tag="OE968_002371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005810116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HCP7219648.1"
                     /translation="MARIAGVDLPREKRAEIGLTYIYGIGKATANEILAKAEINPDTR
                     IKDLSEDQVNELRKVIDDDFLVEGDLRREIALNIKRLRDIKCYRGIRHAKGLPLRGQR
                     TKTNARTRKGPRKTVSRKKKK"
     gene            14141..14539
                     /gene="rpsK"
                     /locus_tag="OE968_002372"
     CDS             14141..14539
                     /gene="rpsK"
                     /locus_tag="OE968_002372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006440523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HCP7219649.1"
                     /translation="MAKPKKKVTRIRRRERKNIERGHAHIQSTFNNTIITLTDVHGNA
                     ISWASSGQLGFKGSRKSTPFASQMAAETAAKAAMEHGLKSVEVFVKGPGSGREAAIRA
                     LQATGLEVTMIKDVTPIPHNGCRPPKRRRV"
     gene            14571..15194
                     /gene="rpsD"
                     /locus_tag="OE968_002373"
     CDS             14571..15194
                     /gene="rpsD"
                     /locus_tag="OE968_002373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HCP7219650.1"
                     /translation="MARYTGASCRQCRREGMKLFLKGDRCYTDKCAIVKRNYAPGQHG
                     QGRKKVSNYGLQLREKQKVKRIYGVLETQFRNLYERAENMPGKAGENLLSLLERRLDN
                     VVYRMGLASSRKEARQLVTHGHFTLNGNKVDIPSLIVKVGDVIEVKEKSRSSAKFKNL
                     VEVNSRIAPKWLEANVEGMTAKVVGVPTREDIDLEIAEHLIIELYSK"
     gene            15272..16219
                     /locus_tag="OE968_002374"
     CDS             15272..16219
                     /locus_tag="OE968_002374"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HCP7219651.1"
                     /translation="MIEIEKPKVDIVELSEDYRYGKFVIEPLERGYGITIGNALRRIL
                     LSSLPGVAVNAIKIDGVLHEFSTIPGVKEDVTEIILTLKELSATIDGEGSRTLKIEAQ
                     GPCSITGADIICPPDVEILSKDLAIATLDDNAKLNMEIFVDKGRGYVSAEENKTENVP
                     IGVLPVDSIYTPVEKVSYHVENTRVGQKTDYDKLVLEVWTNGSINPQEGISLAAKVLV
                     EHLNLFIDLTEHVSSVEIMVEKEEDQKEKVLEMTIEELDLSVRSYNCLKRAGINTVEE
                     LANKSEDDMMKVRNLGKKSLEEVIQKLEELGLGLKPSEE"
     gene            16240..16581
                     /gene="rplQ"
                     /locus_tag="OE968_002375"
     CDS             16240..16581
                     /gene="rplQ"
                     /locus_tag="OE968_002375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003357477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HCP7219652.1"
                     /translation="MAKYRKLGRETAHRNLMLRNLVTCLLRSGRIETTVTRAKETRRM
                     AEKMITLAKRGDLHARRQVLAYVMDETVVNNLFTDLAPKYAERNGGYTRIIKIGPRKG
                     DAAEMAFIELV"
     gene            16701..17534
                     /locus_tag="OE968_002376"
     CDS             16701..17534
                     /locus_tag="OE968_002376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HCP7219653.1"
                     /translation="MDNIVKVNNISFEYITDEAKLKAIDNLSLDVKKGEFVAIIGHNG
                     SGKSTLSKNLNAILMPTEGNILIDDMDTKEEERLWDIRQTAGMVFQNPDNQIVATIVE
                     EDVAFGPENLGIEPKEIRRIVEESLKSVGMYDLRDRQPHLLSGGQKQRVAIAGIIAMR
                     PKCIIFDEATAMLDPSGRKEVMKTIKRLNKEENITVIHITHFMEEAVEADRVVVMEKG
                     KKILEGTPREVFSKIKMLKEIGLDVPCMTELSSLLIEEGINISSDILTVDEMVMELCQ
                     L"
     gene            17522..18388
                     /locus_tag="OE968_002377"
     CDS             17522..18388
                     /locus_tag="OE968_002377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HCP7219654.1"
                     /translation="MSIIVKNLTHIYNEGMPFASKALDDVSFEIKDRDFVGLIGHTGS
                     GKSTLIQHLNGLLKPSSGEIFINDFNITDKNLNLTEIRKRVGVVFQYPEYQLFEETID
                     KDIAFGPSNLGLEESEIHNRVKASMEAVGLDYEGFKDKSPFELSGGQKRRVAIAGVIA
                     MNPEVLILDEPTAGLDPGGRDEIFNLIKDLHEKKNMTIILSSHSMDDMAKLAKTLIVM
                     NHGSVEFMGTPREVFKSNASKLKDIGLDIPQVLELALKLREKGFDISEDILTLEEAKQ
                     EILKVVRGRGLC"
     gene            18382..19185
                     /locus_tag="OE968_002378"
     CDS             18382..19185
                     /locus_tag="OE968_002378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HCP7219655.1"
                     /translation="MLKDITIGQYYPTSSAIHKLDPRIKLVATIVFMVSIFVVNKFWP
                     YIVVLLCLLAMIKLANIPVKYIVKGVKPLKWIILFTFLINIFFLPGDEIWSFGFLAIT
                     KQGLRQAIFMAIRLIFLVVGTSLLTLTTSPIELTDGIERLLNPFKKIGLPVHELAMMM
                     TIALRFIPTLLDETDKIMKAQMSRGADFESKNLINRAKNLVPLLVPLFVSAFRRADEL
                     AMAMEARCYRGGHNRTKMRESVISRRDYMACVFQVVYLGAIIATRFIAI"
     gene            19217..19948
                     /gene="truA"
                     /locus_tag="OE968_002379"
     CDS             19217..19948
                     /gene="truA"
                     /locus_tag="OE968_002379"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003514691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HCP7219656.1"
                     /translation="MRNIKIKIQYNGKNYCGWQKQPDSLGIQGTIERAIYDITKEETS
                     LIGSGRTDSGVHAIGQIANFKINSGISIESIPMALNAKLPKDISVIEACEVNDDFHSR
                     YSAKGKTYKYLVYNSKFRNPILSEISYQVKYELDFDKMCSEAKSLLGTHDFKGFMSSG
                     SSVKDTVRTIYDIDISKKDDLITFEISGNGFLYNMVRIIVGTLVDMGRGRINEPFLDI
                     IQSKTRSRCGHTAPAQGLFLKKVHY"
     gene            20068..20499
                     /gene="rplM"
                     /locus_tag="OE968_002380"
     CDS             20068..20499
                     /gene="rplM"
                     /locus_tag="OE968_002380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HCP7219657.1"
                     /translation="MKSYIAKPADVQRKWYLVDAEGKTLGRLATEIATVLRGKHKPTF
                     TPHVDGGDFVVVVNAEKIVLSGKKLDQKYYRYHTGYVGGLKEISYRDMMDKKPEEVIS
                     HAVSGMLPKNKLRSRMMTRLRVFAGAEHTHAAQNPEVLNFK"
     gene            20528..20920
                     /gene="rpsI"
                     /locus_tag="OE968_002381"
     CDS             20528..20920
                     /gene="rpsI"
                     /locus_tag="OE968_002381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003515879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HCP7219658.1"
                     /translation="MANVQYYGTGRRKSSVARVRLVAGEGNILVNGRALENYFNYETL
                     IRDVKQPLVLTGNENKYDVIVKVEGGGFTGQAGAIRHGISRALLKADLDLRPALKKEG
                     FLTRDARMKERKKYGLKAARRAPQFSKR"
     gene            21379..22131
                     /gene="cwlD"
                     /locus_tag="OE968_002382"
     CDS             21379..22131
                     /gene="cwlD"
                     /locus_tag="OE968_002382"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase CwlD"
                     /protein_id="HCP7219659.1"
                     /translation="MEYYSVFISIHIQGDVVRKYIKHIIFSFAMICLVVVSIFEIKNI
                     SEDVIKYMPVTNKTIILDAGHGGIDPGALNKDKSTSEKDINLAITLKLRELIESSGGL
                     VILTREDDSSLYKEENNKTTRQKYNENLKNRKEIISNSNANMFVSIHLNAFEQSKYYG
                     AQTFYPKDKQDSKELSKCIQEELKRVVDKTNNREVKPRDDIYLLKENNIPSVLIECGF
                     LSNEKECKLLTDETYQEKIAWAIYIGIQKYLS"
BASE COUNT         8969 a         2609 c         4585 g         6150 t
ORIGIN      
        1 gataatatag gagcattatt aagaggagta caaagaaacg agatagaaag aggacaagta
       61 ctagcaaaga ctggatcagt aaaggcacac acaaagttta cagcagaagt atatgtactt
      121 aaaaaagaag aaggtggaag acatacacca ttctttgatg gatatagacc acaattctat
      181 ttcagaacaa cagacgtaac aggagcttgt aagttaccag aaggaataga gatggtaatg
      241 cctggagata acgtaacaat ggaagtagac ttaataaact caatagttgt agaagaggga
      301 ttaagattct caataagaga aggtggaaga acagtagctt caggagttgt tgctacaata
      361 atagagtaat cctttactaa actaatggat ttaatataaa aaaagagggg ggtaactcct
      421 ctcttttttg ttttttgttg acaagtagcg ctaaagcata tatactaaac tagtgccttg
      481 agacagatta acaatcaagt ttaaggttat gatgttgtaa tagaaaataa aattgaaaaa
      541 aacagaaaaa aaacttgaaa aaatgtaaca gatgatataa aatataatag tgtgcttgag
      601 agattaagaa aataataatt aaatcctagt gaaatacgaa ctgatatcga tttaaaagtt
      661 acaacacacc cggagcagtg tatcggtatt ggttgtacgc aacttgaaaa ttaaacacgt
      721 gataaaggag ggaaaacaaa atggctaaga atgaaaaaat aagaataaga ttaaaatcat
      781 atgatcacaa attattagat ttttcagcag gtaaaatagt tgaaactgct aaaaaggctg
      841 gatcacaagt ttcaggacct gtgcctctac caacagaaaa acaagttgta actatattaa
      901 gagctgtaca taagtacaaa gactctagag aacaatttga aataagaact cataaaagac
      961 taatcgacat agctaatcca acacctaaga cagttgactc attaatgaga ttagacttac
     1021 cagcaggtgt agatatagaa ataaaattat aagaacccct aagatattat cctatagatg
     1081 attatcttag aatgattact ctaaaagatg taatccgctg taagaattat aggaggtgct
     1141 aatatgaaag gaatattagg caaaaaagtt ggtatgactc aaatattcac tgataaaggt
     1201 gtagttatac ctgtaacagc tgttgaagca gggcctatgg tcgttactca aataaaaaca
     1261 gttgataaag atggatacaa tgctatacaa ataggttttg aagatgctaa agaaaaagct
     1321 ttaaacaaac ctaaaaaagg acatttagct gctgctaatg ttttaaagaa acatttaaaa
     1381 gaatttagag tagattctgt agaaggatac acagtaggac aagaaataaa agctgatgta
     1441 tttgaagcag gtgcaaaaat agatgttact ggaataagta aaggtaaggg attccaaggt
     1501 ccaataaaaa gacatggaca aagtagaggt cctgaaactc acggttctag ataccacaga
     1561 agaccaggtt caatgggagc ttgttcttac ccaggtagag tatttaaaaa caaaaaatta
     1621 gctggacata tgggaagcgt aaaggtaaca gttcaaaact tagaggttgt taaagtagat
     1681 gctgacaaga accttatatt agttaaagga gctataccag gagctaaagg ttcagtagta
     1741 actataaaag aagctataaa ggtttctaaa taatgactaa cctagagaaa ggaggaataa
     1801 caatgccaaa attaaatgta ctaaatgtta gtggacaaaa cgttggagaa atagaattat
     1861 cagattctat atttggcgta gaagttaatg gacatgtttt atacgaagtt gtaaaaaatc
     1921 aattagcaaa taagagacaa ggaactcaat ctgctaaaac tagagcagaa gttagaggtg
     1981 gcggaagaaa accttggaaa caaaaaggaa caggtagagc aagacaaggt tctacaagat
     2041 ctgtacaatg ggtaggtgga ggagttgctt ttgcacctaa accaagaagc tacaaatata
     2101 cattacctaa gaaggtaaga agattagcta tgaagagtgc tttatcttca aaagttcaaa
     2161 atagtgaagt tatagtatta gatgcattaa acatggatgc tcctaagact aaagaatttg
     2221 ctcaaatatt aaacaatata aatgctgcta aaaaagcttt agtagttata gctgacaaaa
     2281 acgataacgt aataaaatca gctagaaata tagaaggtgt tcaaactgca ttagttaata
     2341 ctatgaatgt atatgatata ttaaaatacg attcatttat aataactaca gatgctgtta
     2401 aaaaagtgga ggaggtgtac gcataatgac taatccacat gatgtaataa taagaccagt
     2461 tgtaactgag cacagtatgg ctgaaatggg tgaaaaaaaa tacacttttg ttgtggctaa
     2521 agatgcgaac aaaactgaaa taaaaaaagc agtagaaaaa gtattcggag ttagtgttga
     2581 taaagtaaat actttaaact acgatggaaa agttaaaaga atgggtagaa ctcaaggaag
     2641 aacatcaagc tttaagaaag cagtagttaa attaactgct gatagtaaag aaatagaatt
     2701 cttccaagga atgtagtatt ataacaaacg aaggagggaa aacagatggc tataaaaaag
     2761 tttagaccaa cttctcctgc cttaagacaa atgacagttt tagtttctga tgaaataaca
     2821 tgtaatcaac cagaaaaatc tcttttagtt aacttaaaga aaaatgctgg tagaaacgta
     2881 catggtagaa taactgttcg tcatagaggt ggaggacaaa aaagaaaata tagaataata
     2941 gattttaaaa gagataaaga tggtatacct gctaaggttg ctactataga atatgatcca
     3001 aacagaactg caaatatcgc attattaaac tatgctgatg gagaaaaaag atatatatta
     3061 gctccagttg gaattaatgt tggagatact atattatcag gattaggtgc tgatataaaa
     3121 ccaggaaact gtttagcatt aaaagatatg ccagttggta ctatcattca taatatagaa
     3181 ttaaagccag gaaaaggagc tcaattagtt agatctgctg gagtttctgc acaattaatg
     3241 gctaaagaag gaaaaaatgc tttattaaga ttaccatcag gtgagatgag attagtaagc
     3301 ataaactgta aagctactat aggtcaagtt ggaaatatag agcatggtaa cgtagttatc
     3361 ggtaaagcag gtagaaaaag acatatggga ataagaccta ctgtaagagg ttctgtaatg
     3421 aaccctaatg accatccaca cggtggaggg gaaggtagat ctccaatagg tagaccatct
     3481 cctgttactc catggggtaa accagctctt ggatacaaaa ctagaaagaa aaataaagct
     3541 tcaaataaac taatagtatc aagaagaact aagtagtaaa tttatttttg ctcggaaagg
     3601 aggaatataa atgtcaagat caactaaaaa agggcctttt gtccatgcaa gacttttaaa
     3661 gaagatagaa gctatgaatg ctagtggaaa taaagaagtt ataaaaactt ggtcaagatc
     3721 ttcaactgta tttccacaaa tggtagaaaa cactatagct gttcatgatg gaagaaaaca
     3781 tgttccagta tatataacag aagatatggt tggacataaa ttaggtgagt tcgttcctac
     3841 tagaactttc aaaggacata aggatgacga aaaatctaat aagagaaaat aattaaatta
     3901 tgactaagaa aggaggaata acaatggaag caaaagctac tgctaaatac gtacgtgtat
     3961 caccaagaaa agcaggccaa atatgtgacc ttgttagagg aaagaatgtt gatgaagcat
     4021 tagcaatatt aaagtttact ccaagaggag cagcttcaat aatagctaag gttgtaaaat
     4081 cagctaaagc taacgcagaa aacaatcacg aaatggatac tgaaaaatta tatatagcat
     4141 caatagttgc taatcaagga ccaacaatga agagattcat gcctagagct atgggtcgtg
     4201 caactacaat aagaaaaaga acttctcata tagaggttgt tgttaaagaa aaaaaataat
     4261 taatagatag gagggaaagt aatgggtcaa aaggttaatc cacacggctt aagggtcggt
     4321 gttataaaag attgggactc aagatggttc gctactgata aaaaagagtt cggaaactta
     4381 ttattagaag accataatat acgtaaattc ttaaagaaaa gattatactc agctggagtt
     4441 gctaagatag aaatagaaag atcagctaac aaaataaaaa tggacttaca cgttgctaag
     4501 cctggtgtag ttataggaag agctggtgca ggaatcgaag cattaaaagc tgaattagaa
     4561 aaaatgacaa agaaaactat aatagttaat atagtagaag taagaagtac agataaaaat
     4621 gctcaattag tagctgaaaa tatagcttta gctatagaga gaagggttgc tttcagaaga
     4681 gcaatgaaac aagctataca aagagcaatg aaatctggtg ctaaagggat aaaagtttct
     4741 gcttcaggaa gattaggtgg agctgaaatg gctagaactg aaggttatag tgaaggaaat
     4801 gtgccactac aaactttaag agcagatata gattatggtt tcgctgaagc tgatacaact
     4861 tatggaaaaa tcggtataaa agtttggata tgtaatggtg aagttttacc aactagagac
     4921 ggtgtaaatc caagagaaga aagcagaaag agcgatagaa gagacaacaa gagagataat
     4981 agaagaaacg atagaagagg aaatgacaga agaggaaatg ataacagagg aaactacaga
     5041 ggacaaagac ctcaaggtgg atcaagacct caaagaactg aaaacaaagg aaattaataa
     5101 tagttaggtt caaggaagga ggaaaaatac tcatgttaat gccaaaaaga gtaaagcgtc
     5161 gtagagttca tagaggaagc atggctgggc aagctcataa gggtaataaa gttacttatg
     5221 gtgagtttgg attagtagca ttagaagctt cttggataac ttctaatcaa atagaagctg
     5281 ccagaatcgc gatgactaga tatataaaaa gagggggaaa ggtttggata aaaatattcc
     5341 ctcataaacc agtaacaaga aaaccagcag agactcgtat gggtgcaggg aaaggttctc
     5401 cagaatattg ggtagctgta gttaagccag gaagagttat gtttgaatta gcaggtgttt
     5461 ctgaagataa agcaagagaa gctatgagac ttgctgcaca taaattacca atcaaatgta
     5521 aatttgttaa aaaagaagat ttagaagtaa agggtggtga ataggatgaa agctaaagaa
     5581 ttaagagatt taacaagcga agagctaatg aacaaattaa acgacttcaa aagtgaatta
     5641 tttagcttaa gattccaatt agctactggt caattagaaa atacagctag aataaagttt
     5701 gttaagaagg atatagcaaa agttaaaact gttcttgctg aaagaaagtt atacgaaact
     5761 agagcttaat ttggaaagga ggctttttaa acatggaaag aggaagaaga aaagttagaa
     5821 taggccgtgt tgttagtgat aagatggata aaacaatagt agtagctgtt gaagaattcg
     5881 tacgtcatcc actatataat aaacgtgtta agagaactaa gaaattcaag gctcatgatg
     5941 aaaagaatat atgtaacatc ggagatagag ttaaaataat ggaaactaga ccattatcta
     6001 aagataagag attcagacta gttgaagttg ttgagaaagt taagtagttt ttgaagaagg
     6061 agggattacg atatgataca acaagaatca cgtctaagag ttgctgataa ctcaggagct
     6121 aaagaacttt tatgtatacg tgttctaggc ggaagtaaaa gaagatatgg taacataggc
     6181 gacgttatag ttgctactgt taaaagtgca acacctggtg gagttgtaaa aaaaggtaag
     6241 gttgttaaag ctgttatagt aagaagcaaa caaggcgtaa gacgtaatga cggaagctat
     6301 atatcttttg atgaaaatgc tgctgttata ataaaggacg ataaaactcc agtaggaact
     6361 cgtatattcg ggcctgttgc tagagagtta agagacaatg aattcatgaa aatagtttct
     6421 cttgctccag aagtactata attaaggagg tgcaatagga catgatgcgt gttaaaaaag
     6481 gtgacactgt tgtagttata gcaggtaaag ataaaggtaa aaaaggttca gttttaaagg
     6541 tatatcctaa aactagcaaa gtgttagttg aaggtgtaaa tgtaataact aaacatcaaa
     6601 aaccaagtgc tatgaaccaa caaggtggaa taataaataa agaagcccca atacacatat
     6661 ctaatgtaat gccatttgat cctgaaacag gaaaaggcgt tagagtaaga tatgaagtaa
     6721 aagatgggaa caaagtaaga gtatcagcaa agagcggaaa agaattataa taaatattgc
     6781 ttgaaaggag ggaccttaaa tggcttctag attacaagaa aaatacatga aagaagttgc
     6841 tcctgcttta atggagaaat ttggatacaa aaacgtaatg gagataccta agttaaataa
     6901 aatagttatt aacatgggta taggtgacgc tagagaaaat ccaaaaggat tagaaaaagg
     6961 cgttgaagaa ttagaaatga tatcaggaca aaagcctgtt ataactaaag ctagaaaatc
     7021 tgttgctaac ttcaaattaa gagaaggaat gccaatagga acaaaagtta cattaagagc
     7081 tgacaaaatg ttctacttca tggacaaatt agtttcagtt tctttaccaa gagttagaga
     7141 ctttagagga gttaacccta atgcttttga tggtagagga aattatgctt taggagttaa
     7201 agaacaatta atattccctg aaatagaata tgataaaata gataaagtaa gaggaatgga
     7261 tataatattt gttactacag caaaaactga cgaagaagct cgtgaattat taaaattatt
     7321 aggaatgcca ttttctaagt aagcaaagga gggattcccg tggctagaaa agcgatggtt
     7381 gttaagcaac aaagaaagca aaagtacgct actagagaat acactagatg tactatatgc
     7441 ggaagaccgc attcagtttt gaaaaaattt ggtatatgcc gtatatgctt tagagaatta
     7501 gcttataaag gtcaaatacc tggtgttaga aaagcaagct ggtagaagct tgattagaat
     7561 ggaaggaggg caacaaaatg acaatgacag atccaattgc agatatgctt actcgtataa
     7621 gaaatgctaa tgttgttaag catgaaactg tagatgttcc agcttctaat atgaagaaag
     7681 aattagctag aatcttatta gaagaaggtt tcataagagg ttatgatgtt atagaagatg
     7741 gaaaacaagg tatcataaga atacaattaa agtacggaca agaaggcgaa agagttataa
     7801 caggtcttaa gaaaatatct aagcctggaa tgagagttta cgctgctaac catgagatac
     7861 caaaagtatt aaacggatta ggaatatcag ttatatctac ttcaaaagga atattaactg
     7921 acaagcaagc tagaaaagaa aatgttggtg gagaagtaat ctgctacgtt tggtaattaa
     7981 tatgaacaat gtaaggaggt gcgaccatgt caagaatagg tgttaagcca ataataatac
     8041 cagcaggtgt tgaagttact atagctgaag gaaatttagt tacagtaaaa ggtccaaaag
     8101 gaactttaac taaacaatta agtgctgagt taaacataaa aaaagaagaa aatacaataa
     8161 tggttgaaag accaactgat aataaaaaac atagatcttt acacggacta actagaactt
     8221 tattagataa tatggttgta ggtgtaaata ctggtttcga aaagaaatta gaattaaaag
     8281 gtgttggata tagagctcaa aaacaaggaa agaaattagt tatgaactta ggtttctctc
     8341 atccagttga gatggaagat ccagaaggaa taactgttga agctccaaac caaacagagt
     8401 taatagtaaa aggtatagac aagcaattag tagggaatta tgctgctaag ataagagctt
     8461 ggagaaagcc agagccatac aaaggtaaag gtataaaata cgttgatgaa gtaatcagac
     8521 gtaaagaagg aaaaactggt aaaaaataat accaaaactt aaacgctaga aaggagtgag
     8581 ctaggtgtta aaaaaggctg ataaaaatgc taatagactt caaagacata agagagttcg
     8641 tagaaaaata agcggtactt ctcaaagacc aagattatgt gtatttagaa gtgctaacaa
     8701 tatatatgct caaataatag atgacacaaa aagagtaact ctagttgctg catcttcttt
     8761 agaagcagaa gttaagagtg ctgtcaatca tacaggaaac aaggaagcag ctaagaaagt
     8821 tggagaatta gttgctaaaa aagctgttga aaaaggaatc actgaagttg tatttgacag
     8881 aggtggatac ttatatcatg gaagaattca agaattagct gaaggtgcta gagaagctgg
     8941 tcttaagttc taatacgaag gagggaaaaa tacatgctac gtcgtaagcc gatagatgca
     9001 ggacaacttg acttacaaga aaaagttgtt gaagtaagac gtgttactaa ggttgtaaaa
     9061 ggtggtagaa atttcagatt tgcagcatta gtagttgttg gagatgaaaa cggacacgtt
     9121 ggtataggtg ctgggaaagc aatggaagta ccagacgcta taaaaaaagc agttgaagat
     9181 gctaagaaaa atctaatagt agtgccaata gttgggacta caattcctca cgaagtacgc
     9241 ggacactttg gtgctggaaa tatattaata atgcctgctg tagaaggtac aggagtaata
     9301 gctgggggac ctgctagagc cgtacttgag ctagctggac taaaagacgt tagagctaaa
     9361 tctttagggt ctaacaatcc aagaaatatg gtaaatgcta caatagaagg acttaattct
     9421 ctaaaaacag ttgaagatat agctaaactt agaggtaaaa aagttgaaga acttctaggg
     9481 taaggaggta gtgtaaaatg gctaaattac aaataaagtt agttagaagt gttataggaa
     9541 ctactcctaa ccaaaaaaag aatgttgaag cgttaggatt aagaaaaaga gaacaagttg
     9601 ttgtaaaaga agacaatgct caaacaagag gtatgataaa taaagtaagt cacttattag
     9661 aagtaactga aatagctgaa taatttttat aaagtagtgc aaggaggtgc aatccatgaa
     9721 gttacatgag ttaaaacctg ctgaaggtgc agtaagagct aagagaagat taggtagagg
     9781 tactgcaact ggacaaggta aaactgcagg acgtggacaa aaaggtcaat ggtctcgttc
     9841 tggtggtgga gtaagagtag gatttgaagg tggacaaatg ccactagcta gaagacttcc
     9901 taagagaggt ttcaataaca tatttaagaa agtttacaca gaagttaatg ttgaagtttt
     9961 aaacagattt gaaaatggaa cagaaataac tgcagaatta ttaaaatcta ctaaaactat
    10021 aagcaaaata ggtaaagacg gaattaaaat cttaggtgaa ggtaatttag agaaagcttt
    10081 aactgttaaa gctgctaaat ttacagcttc agctcaagaa aaaatagaaa aagctggtgg
    10141 aaaagcagag ttagtataat aacctgctaa tctcctagcc agtacaggcg gggtgaatta
    10201 gcgtgctgtc aaaattaaaa caagcttgga agattaaagc agtaagaaaa aaagtaatgt
    10261 atacacttat gatgatcgtg atattcagaa taggtactac tataccagtt ccaggcatag
    10321 acactagtat tatacaaaag atggtaggcg gcaatagtct actttctctg tataatatgt
    10381 ttactggtgg agcatttagt aacttttcac tatttgcttt aggtataagt ccatatatca
    10441 ctgcatcaat cataatacaa cttctaacag taggttttga aagtttagca gaacttcaaa
    10501 aatctggtga agaaggaaag aaaaaaatca ataagtacac taaatataca gcactagctc
    10561 tagcagttgt acaagctttg ggaattacat taggaattgt aagaagtgct ttaatatcaa
    10621 atagtgtgtt ttttatcaca actgttgtaa taacattagt ttcagcaagt atgttagtaa
    10681 tgtggattgg ggacaaaatt actgaaaaag gaatcggtaa tggtagttca gtaataatat
    10741 ttgcaggtat aatatcaaga atacctacag atgttattaa aatatcgcaa caagttaaat
    10801 ctggcgaagt tgcaccttgg gttatagtga ttctagctgt agttatatta cttacagtaa
    10861 caggagttac atttatacaa gaagcaacta gaaagatacc tgtacaatat gctaaaagag
    10921 ttgttggaag aaaaatgtat ggaggacaaa gttctcatat accaatgaaa gttaaccagt
    10981 caggagttat gcctataatt tttgctagtt cacttttagc tttccctcaa acaatagcta
    11041 tgtttatggg tccaaatgct caggcttttg ttcaaaaata cttaagtatg gcaacagaac
    11101 aaggattttg gacatataga tcaattgaga ttctacttat aattttcttc tcatattttt
    11161 atacaactgt atcatttaat acagaagaca tatctaaaaa tatgaaaaat aatggtggat
    11221 ttataccagg tataagacca ggtgagccta ctatggatta tttaaataga attttaacta
    11281 gattaacttt agctggagct actttcttag caataattgc tatggtgcca gctcttacaa
    11341 cacattatat gaaagtaaat atgagtctag ctgggacttc attgctaatc gttgttggag
    11401 ttgctttgga gcttaagaga cagttagagt caaacttagt tatgagaagc tatcaaggtt
    11461 tcttaaaata aaatggagat ggataatatg agaataatat tacttggacc tccaggtgct
    11521 ggtaaaggta ctcaggcggc aggaatagta gaaaaataca atatacctca tatatcaaca
    11581 ggagatatat tcagaaagaa tataaaagag ggaacagaac ttggaaaaaa agctaaagaa
    11641 tacatggacc aaggtttatt agtaccagat gagttaactg taggtttagt tactgataga
    11701 atatctcaag aagattgtaa aaatggattt atgttagatg gatttccaag aaatgtagca
    11761 caaggagaac atttagatat cttcttaaaa aatgctggta tatcactaga taaagttgtc
    11821 aatattgaag ttgataagag tatattagtg tctagagcag ttggtagaag aatatgtaag
    11881 tcttgtggag ctacttacca tgttgagttt aatcctccta aagtagaagg tgtatgtgat
    11941 gtatgccaag gagaattata tcaaagagct gatgataatg aagaaactgt atctaagaga
    12001 atacaagttt atctagatga aactaagcct ttagtagatt attatagcaa acaaggtata
    12061 atagcagata taaaaggtga tcaagcaata gataaagtat ttgaagatat tgtcgcagcc
    12121 ttaggaagtg gaaaataaat gattatcttg aaatcaaaaa aagaaataga acttttaaga
    12181 gaagcaggta aaatagttgc tgacactcat gaagttttaa gaaaagctat ttctccggga
    12241 atatctactt tagaattaga taaaatagct gaagagaata taagaaaata caatgcagaa
    12301 ccttctttta aaggatatgg aggttttcca ggaagtatat gtgcttctat caatagagag
    12361 gtagtacatg gtattccagg agaaactata ttacaagaag gtgacattgt aagtttggat
    12421 ataggagcct attataaagg atatcatggt gattctgcga aaactcacgg agtaggcatg
    12481 atatctgaag aagataggaa attgatagaa gtaactagag aaagcttcta tgaaggaata
    12541 aaatttgcta aattaggata tagactttca gatatctcac acgcagtaca aacacacgtt
    12601 gagaaacatg gtttctcggt agttagagat ttagtgggtc atggagttgg agcaaatctt
    12661 catgaagacc cacaagtacc taattatgga ctcccaggaa aaggaccaag acttagagaa
    12721 ggaatggtta ttgctataga gccaatggtt aatgcaggtc gttatcatgt aaagactcta
    12781 tcagatgggt ggacgactgt tacaatagat ggaaaaaaat cagctcatta tgagcatacg
    12841 atagcaatta ctgaacatga acctttgata ttgacaaagt tgtaatttaa aaagtaggtg
    12901 aaaaaagtgc tatcagataa tttaagtata ggtcaagttg ttaaagtttc attaggacga
    12961 gataaaggaa atttattctt tgtagtcaaa ataattaata atgaatatgt attaatagct
    13021 gatggaaaaa agagaaaact tgacaaacct aagttaaaga aagtgaagca cttaaaaaaa
    13081 tataatttta ttaatgatga agttagaaaa agagtagtat ctggacaaga gattacagat
    13141 tcttttttaa gagctgaact tactaagtta aattagataa tttaacttat tgaaatggag
    13201 ggctggttag ttaatggcca aaaaagatgt tatagaatta gaaggtacag tttcagaagc
    13261 tttacctaat gctatgttca aagttaaact agaaaatgga catgagatat tatgccacat
    13321 ttctggaaag ctaagaatga acttcataag aattcttgaa ggtgacaagg tgaatgttga
    13381 actttctcca tatgacctta caagaggaag aattacttgg cgtaagaagt agactatatt
    13441 aatatttagt ctaaggaggg attaataatg aaggttagac catcagtaaa accaatatgt
    13501 gaaaaatgta aagtaataaa aagaaaagga aaagtaatgg ttatctgtga aaatccaaag
    13561 cataagcaaa agcaaggata agaaattatt actagcattt tgttaaattt tatagtataa
    13621 tactatattg tgatgttaac aaaagaacgt taaaatcgtt gaacaatctg gcgtaggatt
    13681 ggcatatgat gtgaagtttt aaacactaaa aactatgtgt aggaggtgcg atcatggcaa
    13741 gaatagctgg ggtagattta cctagagaaa aaagagcgga gataggctta acttatatat
    13801 atggtatagg taaagcaact gctaacgaaa tattagctaa ggctgagata aatccagata
    13861 ctagaataaa agatttatca gaagatcaag ttaatgagtt aagaaaagtt atagatgacg
    13921 atttcttagt tgaaggtgac ttaagaagag aaattgcttt aaacataaag agattaagag
    13981 atataaaatg ttatagagga ataagacacg ctaaaggtct tccattaaga ggacaaagaa
    14041 ctaagactaa tgctagaact agaaaaggtc ctagaaaaac agtatctcgt aaaaagaaaa
    14101 aataaataaa taataactag atgaaggagg gaaaaggaaa atggctaaac caaaaaagaa
    14161 agttacacgt attagaagaa gagaacgtaa aaatatagaa cgtggtcatg ctcatataca
    14221 atcaactttc aataatacaa taataacttt aactgacgtt cacggaaatg ctatatcttg
    14281 ggcaagttct ggacaattag gattcaaagg atcaagaaaa tcaactccat ttgcatctca
    14341 aatggctgct gaaacagctg caaaagctgc gatggaacac ggactaaaaa gtgttgaggt
    14401 attcgtaaag gggccaggtt caggaagaga agctgcaata agagctttac aagcaactgg
    14461 actagaagta actatgataa aagacgttac tccaatccca cataacggat gcagaccacc
    14521 aaagagaaga agagtgtaat taataagagt acaataggag gtgtagataa atggcaagat
    14581 atacaggtgc atcatgtaga caatgccgta gagagggaat gaaattattc cttaaaggtg
    14641 atagatgtta tacagacaaa tgtgctatag taaaaagaaa ctatgctcca ggtcaacatg
    14701 gccaaggaag aaagaaagtt tctaactatg gattacaatt aagagaaaaa caaaaagtta
    14761 aaagaatata tggagtttta gagactcaat ttagaaattt atatgaacgt gctgaaaata
    14821 tgcctggtaa agcaggtgag aacttattaa gtttattaga gagaagatta gataatgtag
    14881 tttacagaat gggactagca tcttctagaa aagaagctag acaattagtg actcatggtc
    14941 atttcacttt aaatggaaat aaagtagaca taccttcatt aatagttaag gttggagatg
    15001 ttatagaagt taaagagaaa tcaagatctt ctgcaaaatt caaaaattta gtagaagtta
    15061 actcaagaat agctcctaag tggttagaag ctaatgtaga aggaatgaca gcaaaagtag
    15121 ttggtgttcc aacaagagaa gatatagatc ttgagatagc agagcactta atcatagaac
    15181 tttactctaa ataataagca cacttttaaa aattatttta aaattttgtt taccctcagt
    15241 ggattactga attttaagga gggttttgtc catgatagaa atagaaaagc caaaagtaga
    15301 tatagttgag cttagcgaag actatagata tggtaagttt gttatagagc ctctagaaag
    15361 aggatatgga ataactatag gtaacgcatt aagaagaata ttattatcat cattaccagg
    15421 tgtagcagtg aatgctataa aaatagatgg agttcttcat gaattttcaa caatacctgg
    15481 tgttaaagaa gatgttactg agataatatt aactttaaaa gagctttcag caactataga
    15541 tggtgaagga agtagaacac ttaaaataga agctcaagga ccatgctcta tcacaggtgc
    15601 agatataatc tgtcctccag atgttgaaat attaagtaaa gatttagcaa tagctacatt
    15661 agatgataat gctaaactta atatggagat atttgtagat aaaggtagag gttatgtttc
    15721 tgctgaagaa aataaaacag agaatgttcc aataggtgtt ttacctgtgg attcaatata
    15781 tactcctgtt gagaaggtta gttatcatgt ggaaaacaca agagttggtc aaaaaacaga
    15841 ttatgataaa ttagtattag aagtttggac taatggtagt ataaatcctc aagagggaat
    15901 atcattagct gcaaaggtat tagttgagca tttaaactta tttatagact taactgaaca
    15961 tgtaagtagt gttgaaatca tggtagaaaa agaagaagat caaaaagaaa aagttcttga
    16021 aatgactata gaagaattag atttatcagt tagatcatat aactgtttaa agagagcggg
    16081 aattaataca gttgaagaat tagctaataa atctgaggat gatatgatga aggttagaaa
    16141 cctaggtaag aagtcattag aagaggtaat acaaaaacta gaagaacttg gattgggatt
    16201 aaaaccaagt gaagaatagc gagcaaagga gggataagaa tggctaagta ccgtaaatta
    16261 ggacgtgaaa cagctcacag aaaccttatg ttaagaaact tagtaacttg cttactaaga
    16321 agtggaagaa tagaaactac agtgactaga gcgaaagaaa ctcgtagaat ggctgaaaag
    16381 atgataactc ttgctaagag aggagatctt catgctagaa gacaagtttt agcttatgtt
    16441 atggatgaaa cagtagttaa taacttattc acagatttag ctccaaaata tgctgagaga
    16501 aatggtggat acactagaat aataaaaata gggccaagaa aaggcgatgc tgctgaaatg
    16561 gcttttatag aattagtata gtaaggaaag gattaggctt gatggcttaa tctttttttt
    16621 atttttttga ctaaggtatg atataataat gtgtaaaatg atttttataa gttattgctt
    16681 actaaaagga gtatgagtta atggataata tagtaaaggt aaataatatt tcgtttgagt
    16741 atattacaga tgaagcaaaa cttaaagcaa tagataattt aagcctagat gttaaaaaag
    16801 gagaatttgt tgcgataata ggacataatg gttctggtaa gtctacttta tctaaaaact
    16861 taaatgctat tcttatgcct actgaaggaa atattcttat tgatgatatg gatactaaag
    16921 aagaagaaag attatgggat ataagacaaa ctgcaggcat ggtatttcaa aatccagata
    16981 atcaaatagt tgctactata gtagaagaag acgttgcatt tggacctgag aacttaggta
    17041 tagaaccaaa agaaataaga cgaattgtag aggagtcttt aaaaagtgta ggtatgtatg
    17101 atttaagaga tagacagcct catttgttat caggaggtca aaagcaaaga gttgcaatag
    17161 caggaattat tgctatgagg cctaaatgta taatatttga tgaagcaaca gcaatgttag
    17221 atccatctgg aagaaaagaa gttatgaaaa caataaaaag acttaataag gaagaaaata
    17281 taactgttat acatataacg cactttatgg aagaagcagt agaagctgat agagttgtag
    17341 ttatggaaaa aggaaagaaa atcttagagg gaactcctag agaagtattc agtaaaataa
    17401 agatgttaaa ggaaatcggt ttagatgtac cttgtatgac agagttatct agtttattaa
    17461 tagaagaagg tataaatatt agtagtgata tattaactgt ggatgagatg gtgatggaat
    17521 tatgtcaatt atagtaaaga atttaacaca tatatataat gaagggatgc cttttgcaag
    17581 taaggcactt gatgatgttt cttttgagat taaagataga gattttgttg gtcttatagg
    17641 tcatacaggc tcaggaaaat ctacattaat acaacattta aatggattac taaagccttc
    17701 ctcaggagaa atatttataa atgattttaa tataacagat aaaaacttga atttaactga
    17761 gattagaaaa agagtagggg ttgtatttca atatccagaa taccaattgt ttgaagaaac
    17821 gattgataaa gatatagctt ttggaccctc taatttaggc ttagaggagt ctgagataca
    17881 taacagggta aaagcatcaa tggaagctgt aggacttgat tatgagggat ttaaagacaa
    17941 atctcctttt gaattatctg ggggacaaaa gcgtagagta gcaattgctg gagttatagc
    18001 catgaaccca gaagttctca tattggatga accaactgct ggtcttgacc ctggtggaag
    18061 agatgaaatt tttaacttaa taaaagactt acatgaaaaa aagaatatga ctataatact
    18121 atcatcacat agtatggatg atatggcaaa gttagcaaaa actttaattg ttatgaatca
    18181 tggtagcgta gaatttatgg gaactcctag agaagtgttt aaatcaaatg ctagtaaatt
    18241 aaaagatata ggattagata ttccacaagt tttagaactt gcattgaaat tgagagaaaa
    18301 aggctttgac atcagtgagg atatattgac tttagaagaa gcaaaacagg aaatattaaa
    18361 agttgtgaga ggacgaggat tatgttaaaa gatataacta tagggcaata ctacccaaca
    18421 agttctgcta ttcataaatt agatccaagg ataaagcttg tagcgacaat tgtatttatg
    18481 gtatctatat ttgtagtaaa taaattttgg ccttatatag tagttttatt atgtttatta
    18541 gctatgataa aattggctaa tataccagtc aaatatattg ttaagggtgt taaacctctt
    18601 aaatggatta ttttgtttac atttcttata aatatttttt tcttaccagg tgatgaaata
    18661 tggtcatttg gatttttagc tattacaaaa cagggtctaa gacaagcaat ttttatggca
    18721 ataagattaa tatttttagt agttggtaca tcattgctta ctttaacaac ttcaccaata
    18781 gaattaactg atggaataga gagattgttg aatccattta agaaaattgg tttgccagtt
    18841 catgaacttg caatgatgat gacaattgct ttacgtttta ttcctacatt gttagatgag
    18901 acagacaaaa taatgaaggc tcagatgtct agaggtgcag attttgaaag taagaatctt
    18961 ataaatagag caaagaattt agtaccactt ttggtacctt tatttgtaag tgcatttaga
    19021 agagctgatg aattggctat ggccatggag gccagatgtt acagaggtgg acataatagg
    19081 actaagatga gagagtctgt tatatcaaga agggattata tggcatgtgt atttcaggtt
    19141 gtttatctgg gagcaattat agctactaga tttatagcaa tttaattaat aagttataga
    19201 tataatgagg taaagtatga gaaatataaa aattaaaatc caatacaatg gtaagaatta
    19261 ttgtggatgg caaaagcaac ctgattcttt agggatacaa ggtacaattg aaagggctat
    19321 atatgatata acaaaagaag aaaccagtct tatagggtct ggtagaactg attcaggagt
    19381 tcatgctatt ggtcagattg caaattttaa aattaattca ggtataagta tagaaagtat
    19441 accaatggca ctaaatgcca agttgccaaa agacatatca gttatagaag catgtgaagt
    19501 aaatgatgat tttcactcca gatacagtgc aaaaggtaaa acatataaat atttagtata
    19561 taatagcaag tttagaaatc caatacttag tgagatatca tatcaagtaa aatatgaact
    19621 tgattttgat aaaatgtgtt cagaagcaaa aagtttatta ggaacacatg attttaaagg
    19681 ttttatgagt tctggttcat ctgtaaaaga tacagttaga acgatatatg atattgatat
    19741 aagtaaaaaa gatgacttga ttacttttga gattagtggt aatggttttt tatataacat
    19801 ggtgaggatt attgttggaa cacttgttga tatgggtcgt ggcagaatta acgaaccatt
    19861 tttagatata atacaatcaa aaactaggtc aagatgtgga catacagctc cagcacaagg
    19921 attatttctc aaaaaagttc attattaact tgacacacca ggctacatgt attaaaatat
    19981 atgagaatgt gttaataagt ccacttgccc cggacttgac ataaacggta aaaaaatttt
    20041 atgaaaagta gttaaggagg gacagttatg aaaagttata tagctaagcc agctgatgta
    20101 caaagaaaat ggtacttagt tgatgctgaa ggaaaaacat taggtcgttt agcaacagaa
    20161 attgcgacag tattgagagg taaacataaa ccaacattta ctcctcacgt tgatggtgga
    20221 gattttgttg ttgtagtaaa tgcagaaaaa atagttttaa gtggtaagaa attagatcaa
    20281 aaatattaca gataccatac tggttatgta ggtggattaa aagaaatatc ttacagagat
    20341 atgatggata agaaaccaga agaagttata tcacatgctg taagcggtat gttacctaaa
    20401 aataaattaa gaagcagaat gatgactaga ttaagagtat ttgcaggtgc tgagcacact
    20461 catgcagctc aaaatccaga agttttaaac tttaaataag attaataggt gaaaggagga
    20521 gtttataatg gctaacgttc aatattatgg aactggaaga agaaaaagtt ctgttgctag
    20581 agtaagacta gttgcaggtg aaggaaatat attagtaaat ggaagagcat tagaaaatta
    20641 ttttaattat gagacattaa taagagatgt taaacaacca ttagttttaa ctggtaatga
    20701 aaataaatat gatgttatag taaaagttga aggtggagga ttcactggac aagctggagc
    20761 tataagacat ggaatatcta gagctttatt aaaagctgat ttagatttaa gacctgcttt
    20821 aaagaaagaa ggtttcttaa ctagagatgc aagaatgaag gaaagaaaga aatacggatt
    20881 aaaagcagca agaagagctc cacaattctc aaaaagataa ttacttattt ttttggaaaa
    20941 gcaaaatcct ttatttactg ttattcagaa agtattggta ttttaaaaat gttgggttaa
    21001 gttaattatt gatatataat aaaataataa gatatcttat taggatgttt ttcattaaga
    21061 agaacatcct ttttattttg actatttaat aaaaaacata tgctaataag atttaaattt
    21121 tatttttata atattgtaat ttaaaagttt atataaggtt atatatttta agatattatt
    21181 taacaatata aattctgaat atacgttatc aaagtttata atataaacta agtataattt
    21241 attgtatagt attgaatgtt agataaacat agtgaattaa ataggggcag aaatataata
    21301 tcattacata ataatatatt aataccaata aataaagata tatcaatatt aaaaaaattt
    21361 aaatgtttgt actaatatat ggaatattat agtgttttta taagtataca tatacagggt
    21421 gatgttgtga gaaagtacat aaaacatata atttttagtt ttgcaatgat atgtctagta
    21481 gtagtatcca tatttgaaat taaaaatatt tctgaagatg ttatcaagta tatgccagta
    21541 acaaacaaaa ctataatttt agatgctggt catggaggca ttgatccagg tgcattaaat
    21601 aaggataaga gtacatctga aaaggatatt aacctagcaa taacacttaa gcttagagag
    21661 cttatagaat caagtggtgg ccttgtaata ttaactcgag aagatgacag tagcctttat
    21721 aaagaagaaa ataataaaac tacaagacaa aaatataatg agaatttgaa aaatagaaaa
    21781 gaaataatat ctaattctaa tgccaatatg tttgtctcta tacatcttaa tgcatttgaa
    21841 caatcaaaat actatggagc tcaaactttt tatcctaaag acaaacaaga cagtaaagaa
    21901 ttatcgaagt gtattcaaga agaacttaaa agagtagtag ataagacaaa caacagagaa
    21961 gtcaaaccaa gggatgatat atatcttttg aaagaaaata atattccatc agtactgata
    22021 gaatgtggtt ttttatcaaa tgaaaaagag tgtaaactct taactgatga aacatatcaa
    22081 gaaaaaatag catgggcaat ctacatagga atacaaaaat atttaagttg aaataactat
    22141 aaaaataggt ctaaatatgt aaatagcttg tattaaagca gttaaaatgc attaatatag
    22201 gctattttta ttttgacaaa aaaatattta aaataaaagt taaaaagttg ttgacttaga
    22261 ataatataga tgatattata tatgagtgcc caaaaggagc accaaaataa gac
//
LOCUS       DAJMZY010000065        22105 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.065, whole genome shotgun sequence.
ACCESSION   DAJMZY010000065 DAJMZY010000000
VERSION     DAJMZY010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 22105)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22105)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22105
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.065"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            <1..991
                     /locus_tag="OE968_002383"
     CDS             <1..991
                     /locus_tag="OE968_002383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ComEC/Rec2 family competence protein"
                     /protein_id="HCP7219660.1"
                     /translation="KSTGYKGIVYINNYKIIDKNKLYSLIGEIKFYISKTYRYLYKKN
                     SDFINSILLAEVENLTEEQKEIFTRTGTSHVISISGLHTGILCVIISFLLRGINKLYK
                     LLILSIFITLYCIMVGASPSIIRSIAFVMIFYLSIFIDRKKDGISALSLIGIILIMNN
                     PYVIYNVSFQLSFLATLSILIFYNKINSIIKLSMVSLTISSNILTLPIIYYTFKGIPL
                     LSIIGNLIIVPFVGVIMYLSIASLIVFKVSVVIAKIISFFNSTFIESIFFLLEKISNL
                     SFAYINIENPKFYIVVIYYIGVFFYIFYIEGKEIKEQENELQGYYKECKREKL"
     gene            945..1988
                     /gene="holA"
                     /locus_tag="OE968_002384"
     CDS             945..1988
                     /gene="holA"
                     /locus_tag="OE968_002384"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HCP7219661.1"
                     /translation="MNYKDIIRNVKEKNFEKMYLFYGREYYLIENAIKAFKDSLNEGM
                     LDFNLDIIDGKEIVLNQLISSIETLPFMDDRKIVIIKDFELLKGKKKNFTDSDEKYLI
                     EHLDNIPDTTTIVFVVYGDVDKRKSLVKKIGNNGIVFDCDKLSDMDLFKWIKKSFALN
                     DVIIDNSQIMYFIEQEGYRDKSSEKTLSDLENEINKISSFVGKGNNVTNDVIDKLSQK
                     KVENDIFKLIDYIGEQNASNAMKILNDMIQEGESVLGIFSMIARQFKIIMQVRQLQLD
                     GYSTKLIADKLKMHQFVVGKALKQTKNFSDDIIVEILNYILESDYKIKTGLIRDTLAV
                     EMLVSRYCKREAI"
     gene            complement(2175..2441)
                     /gene="rpsT"
                     /locus_tag="OE968_002385"
     CDS             complement(2175..2441)
                     /gene="rpsT"
                     /locus_tag="OE968_002385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HCP7219662.1"
                     /translation="MANIKSAKKRISVIEKKTALNRVRKSQIKTAIRRFEDAVAAGNR
                     EDAVAKFQYAQKRIYQVASKGTIHKNAAARKVAKLAQKLNGMNA"
     gene            3037..3558
                     /locus_tag="OE968_002386"
     CDS             3037..3558
                     /locus_tag="OE968_002386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCP7219663.1"
                     /translation="MDIAKLILNPARLRILQYIRLYGSVRTSDIVKYLNDIPRATVYH
                     HVKILEENNMIEVIKENRVRGTIEKVYALKEYTTSMEGETFVALSTAFYVGLMQEMNE
                     YFSRKEQDHKKDNVFFSSALLYMSDNEYENLLKSIADLLKPYIEQKPKSNLKLRKLSI
                     ISSPPVADNDKTK"
     gene            3592..4368
                     /locus_tag="OE968_002387"
     CDS             3592..4368
                     /locus_tag="OE968_002387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HCP7219664.1"
                     /translation="MKFHEFGNKNRPHIMLIHGGGNAWWNYLRQAEVLSNKYHVILPT
                     LDGHGEEYETTYISTEDTADKLISYIDENCSGHLFALCGVSLGGQIVMELLSRKPNIT
                     KKAIIDGSICYPRPLMARFCIAGIRFFGGLLFSEKACRFQIAMMPKLLPENMQYPDEI
                     KAYYMTDMPHVRKETFYNMYRTYMMNYTLKENVKKTTAQVMYWYGEKEMKCVKKSAKL
                     FQSYVPSCEIYEAKSYNHGYLSLYLPNEWLEIAEPFFQKE"
     gene            4710..5663
                     /locus_tag="OE968_002388"
     CDS             4710..5663
                     /locus_tag="OE968_002388"
                     /EC_number="3.4.24.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GPR endopeptidase"
                     /protein_id="HCP7219665.1"
                     /translation="MISVRTDLALEASEMCEKSQEGSSIPGVKIETKELENCIVTKVE
                     VIDRQGAEIMNKDIGKYITLESNLMKFDDDESREEMISYLKEELVDIFGQDKNKKTLV
                     IGLGNRNITSDALGPKSVSKTLVTRHLFKNYNKDYDDDFTEVSALSPGVMGVTGIETS
                     EIVKSLVEKVKPDRVVAIDALASRKMERVNSTIQISTAGISPGGGVGNTRKSLTKETL
                     GVDVIAIGVPTVVDAATLTIDVLDMAIDNLIAQSEETESFYEMLKKLKEEEKYHLIKD
                     SLDPYDKNLIVTPKDIDDTIENLSIIISEGLNRSLHPGRLV"
     gene            5681..6700
                     /locus_tag="OE968_002389"
     CDS             5681..6700
                     /locus_tag="OE968_002389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein P"
                     /protein_id="HCP7219666.1"
                     /translation="MFKKCIKVVTLTFILVCILPGKSLALNQDDFLKFLVNSSYPEAK
                     VEGNDTENKKNNKNKETSKENKEESKEGNTKSKDASKVDNKKESEKEYIKLYVGKENV
                     PDIESKNSDTTETNTTSSSDYKDDLRVTKENPRILIYHTHGCETYSNSPDGNYHSRDK
                     KNSVMEVGSALTSALDSKGWGVVHTTKYHDYPSYNNSYASSLKTIQSILPKYNSVDIA
                     IDLHRDARDLTNPATKEKDHLKYTTMINGERVSKFFFVVGGKNTNRKQLRALAEDITA
                     FAEKKYPGLVSPIVEKDYARFNQFAVKNHMLVEIGNNATSVEESKATTKYLAEILDEY
                     FKQKN"
     gene            6731..6982
                     /locus_tag="OE968_002390"
     CDS             6731..6982
                     /locus_tag="OE968_002390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219667.1"
                     /translation="MSRLEKNIESKSKLRKYKYIMRILFLITMIICTSVCVFIVDSNA
                     KSMLGMKQYDFPSIKFDITKFDFDIPNFDIHEIIKKFNK"
     gene            7264..9069
                     /gene="lepA"
                     /locus_tag="OE968_002391"
     CDS             7264..9069
                     /gene="lepA"
                     /locus_tag="OE968_002391"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HCP7219668.1"
                     /translation="MDNKQSRTRNFSIIAHIDHGKSTLADRLIQQTGLVSERDMKSQL
                     LDNMDLERERGITIKLQNIRLMYKAKDGNEYYLNLIDTPGHVDFNYEVSRSLAACEGA
                     LLVVDAAQGVEAQTLANVYLAIDQDLEILPIINKIDLPSARPEEVKNEIEDLIGLDSS
                     EAPLISAKTGLNIEDVLEDIVKNVPPPKGDNEAPLKALIFDSYYDAYKGVVAYVRVFE
                     GTVKKGMTIKMMNTNKKFEVTEVGVMAPGQTELSELSAGDVGYIAASIKDIRSCRVGD
                     TITDSNNPTEEPLPGYKKATPMVYCGIYPGEGEKYENVRDALEKLQVNDAALEYEAET
                     SAALGFGFRCGFLGLLHMEIMQERLEREFNLDIITTAPSVIYRVTKMDGEVVMIQNPA
                     NLPEPSEIKMIEEPIVKGDIIVPKDYVGVVMELCQERRGNMLNMEYIDDRRVMLHYDL
                     PLNEVVYDFFDALKSRTRGYGSLDYEVKGYVASTLVKLDILINKEQVDALSFIVHETR
                     AFPRGKAMCEKLKGEIPRHQFAIPIQAAVGNKVIARETISALRKDVLAKCYGGDISRK
                     KKLLEKQKEGKKRMRQIGSVEVPQKAFMSVLKLDE"
     gene            9218..10555
                     /locus_tag="OE968_002392"
     CDS             9218..10555
                     /locus_tag="OE968_002392"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HCP7219669.1"
                     /translation="MINIEIPKKVDYIIKELEKNGYEAYIVGGCVRDCLLERVPNDWD
                     ITTSARPEVVVELFEKTIPTGIQHGTVTVMIEHEPFEVTTYRIDGNYSDGRHPDSIEF
                     TNNIVKDLSRRDFTINSIAYNSKTGLVDPFNGYEDIQNKYIRCVGNPVDRFEEDALRM
                     LRAVRFSAQLNFKIAEGTKQSIHKKADLIKNVSIERIQTEFNKILVSDSSKLNLLKST
                     GLLKFIIPEICELEDVTQHNPYHIYDVQKHTLIATEVIEDELYLKLTMLFHDLGKKVT
                     KTTDKNGVDHFYTHSRESVKIAKKILKRLKYDNYTINKVLILIQYHDYRIEPKRKIIK
                     KLLNKLEDVELFEDLIKVNWADTLAKNPKYAKQKILNLIECEKEFKHIINQKECFNLK
                     DLAINGKDLISIGIKPGKDIGYILNKMLEIVINNPELNEKEILKEKALNIYTF"
     gene            10788..12101
                     /locus_tag="OE968_002393"
     CDS             10788..12101
                     /locus_tag="OE968_002393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCP7219670.1"
                     /translation="MHTQLQKTIGLSAALSTVVGMVIGSGVFFKPQAIYTTTNGAPGL
                     GIIAWLLGGFITITAGLTATEISAAIPKTGGMMIYIEEIYGEKLGFLTGWMQTVLFFP
                     GTSAALGVIFAQQASELLGMSPNNMANVLPIAIGVILFLALLNIIGSSLGGKVQTVAT
                     IGKMIPLILIIVFGFIKGQSSEVLNPFVGDGVNASNALGQVLIATLFAYDGWINVGAI
                     SGEMKSPEKDLPRAIVGGLSLVMAVYIIINIAYLWVVPASELATVTSPATLVATRLFG
                     NIGGKVITVGILISVFGTLNGYLLTGSRIPYTLAEMGTLPASKTLLKVNSGGSPVNSI
                     LLITVLACVYALSGQFNLLTDLTIFSIWVFYVLTFIGVMRLRRQKPDLHRPYKVPLYP
                     IIPIIAILGGLFVIINQILTSTVISLGGIFITLLGLPVYYYMKKR"
     gene            12273..13448
                     /locus_tag="OE968_002394"
     CDS             12273..13448
                     /locus_tag="OE968_002394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HCP7219671.1"
                     /translation="MLGLYVHIPFCVKKCKYCDFNSYKMDIDSKKRYIEDLKIEMELY
                     SNKLYKDNKYKNKECCSLNKNDKITSIFVGGGTPSILTSDEIREVFISIKEMFDIDEN
                     AEITIECNPGTLTLEKLKTMKEIGINRLSIGLQAIQEKHLNFIGRIHTYEEFEKNYKD
                     ALSVGFKNINIDLMYSLPNQTLCDWKETLEKVVHLNPTHISAYSLILEEGTELYNMYE
                     SNKFELIDENVDIEMYEYTINYLKSKGYNQYEISNYSKEGYNCEHNILYWECEHYIGI
                     GAGASGYINENRYNNVESLEDYHLSLVKREKPIQENEILSEKDMIEEKIFMGLRMNKG
                     IKFEDFKKKFGIDFREKYNKQIEMLLARKLINQSFEGIQLTQKGREISNSVFIEFME"
     gene            13551..14570
                     /gene="hrcA"
                     /locus_tag="OE968_002395"
     CDS             13551..14570
                     /gene="hrcA"
                     /locus_tag="OE968_002395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcription repressor HrcA"
                     /protein_id="HCP7219672.1"
                     /translation="MELNERKLNILKAIVKDYIETAEAIGSRTISKRHDLGVSAATIR
                     NEMADLEELGYLIQPHTSAGRVPSEKGYKLYVNSLMSKSELDDNDKILIEQCMNHNIN
                     HIKELIHETSKLLSQLTNYTTVAVTKSLINQSVIKHIQLVAMNDNNILLIVVTDKGDL
                     KKANLTTNVYLDQSKLNLISDNLTRKLLGKSITDLDDNLIAFIKYEISEYSGLIDELL
                     NALNSNMKEEDFSLSLNGATNIFSYPEFNDVLKAKSFLNMLEKKETIADIIKSKGIQK
                     DNLNIIIGSDNDCELAQDCSIVTATYNVDRDLVGRISFIGPTRMDYARIYSIINYMSL
                     LINRK"
     gene            14600..15220
                     /gene="grpE"
                     /locus_tag="OE968_002396"
     CDS             14600..15220
                     /gene="grpE"
                     /locus_tag="OE968_002396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HCP7219673.1"
                     /translation="MDKKNEQQEVREENDTSINQESETQVELEEEVVNEECETSSEKT
                     DEKEVDDENVTDINSKLAEKKLQDELDELNDKYQRLQAEYANYRRRTQQEKETIGVFA
                     NEKIITELIPVIDSMERALDACEDKEDTMYKGISLVHKQLIDTLVKFGVEEIEAESKE
                     FDPNLHLAVMQESVDGVEANQIVMVLQKGYKLGTKVVRPSMVKVSC"
     gene            15312..17159
                     /gene="dnaK"
                     /locus_tag="OE968_002397"
     CDS             15312..17159
                     /gene="dnaK"
                     /locus_tag="OE968_002397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000034699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HCP7219674.1"
                     /translation="MGKIIGIDLGTTNSCVAVLEGGEAQIIANSEGMRTTPSVVAFTK
                     DGERIVGEPAKRQAVTNADKTITSIKTHMGTDYKVNIDGKSYTPQEISAIILQKLKSD
                     AESYLGQTVTEAVITVPAYFTDAQRQATKDAGRIAGLDVKRIINEPTAAALAYGMDKL
                     DQEKKILVFDLGGGTFDVSILEIGDGTFEVLATAGNNRLGGDDFDQIVIDYLAEEFKK
                     AEGVDLRNDKMALQRLKEAAEKAKKELSSTMSSNINLPFITATAEGPKHLNIDLSRAK
                     FEELTRGLVEKTMEPTKTALQDAGLSTGDIDDVLLVGGSTRIPAVQEAVKKFIGKEPH
                     KGINPDECVAAGASIQAGVLAGDVKDLLLLDVTPLSLGIETMGNVMTKIIERNTTIPT
                     KKSQIFSTAADNQTAVDIHVLQGERSMAYDNTTLGRFQLTDIPPAQRGIPQIEVTFDI
                     DANGIVNVSAKDLGTGKEQKITITSNTNLSESEIEQKIKEAEMNAEADKQKKEKIEAF
                     NQAESTIYQTEKTLNELGDKISSGEKEDIEKAIADLKAVKDNQDATAEELKKATDEVM
                     TKFQKVSQEMYQKAAQEQQAAQGAEQAQDNGPKDDNVVDADFKEVDEDK"
     gene            17370..18524
                     /gene="dnaJ"
                     /locus_tag="OE968_002398"
     CDS             17370..18524
                     /gene="dnaJ"
                     /locus_tag="OE968_002398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HCP7219675.1"
                     /translation="MSTKRDYYEVLGISKGAEAQEIKKAYRKLAMKYHPDRNPGDKEA
                     EEKFKEINEAYEVLSDDTKRKTYDQFGHDGLNGQGGFGGQGGFGGQGFGGFEDMFGDI
                     FGDMFGGSFGGGRARRRGPQRGADIRQSVTISFEEAAFGKKMSIKVNRSEECEECNGT
                     GAKPGTSKKTCSTCNGTGQVRTVQRTPFGNIASSRPCSACNGTGEVIESPCSKCHGTG
                     NTRKVKTIEVDIPAGIDDGQMIKLSGQGEVGEKGAPRGDLYIVVNVKSHPLFTRDGND
                     IYFEMPITFVQATLGDEIEVPTLDGKVKYSVPEGTQTGTVFRLKEKGIPRIRGNSRGD
                     QYVKVVVEIPKKLNDKQKELLREFAKECGSNVHEKKKTFGQKIEDMFKKK"
     gene            19490..20425
                     /locus_tag="OE968_002399"
     CDS             19490..20425
                     /locus_tag="OE968_002399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HCP7219676.1"
                     /translation="MYYIGVDIGGTGIQAGVVDNYGKIIFRSECKTVIEKGFEGILND
                     IKIMIYKLLEDNKLTMSDIKSIGFGVPGFINKEGLVTCVNLKWNKKAFNKELKKRFPD
                     VEIHGENDATVAALGEAKFGSMKGANVGVLYTLGTGVGGGIVINQKVFSGAHGLGSEI
                     GHQIIGENYFNCNCGNNGCVETFCSATAIIKYSQKLIEEGEKSRILDLAEGNLENVNA
                     KMVFDAYRENDLVAIKVINRFKEYLAKTFANTINSLDPEIISIGGGISKSSDIILDGI
                     EGLVRKFVLYKTEDIATITCATLGSDAGIIGAAFL"
     gene            20461..21834
                     /locus_tag="OE968_002400"
     CDS             20461..21834
                     /locus_tag="OE968_002400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCP7219677.1"
                     /translation="MGKTNARRTLFLIAIGSGTMLNPLNSSMISLALHSIQNDFHISF
                     TTVSWIVSAFYLASAIAQPVSGKIGDLIGRKVLFLSGLMLVILSASIVPLVQSFFILI
                     FIRVIQAIGTSTLYPSGVALIQNNIKERQSSALAVLTIFASTTAGLGPTLGGLLLDLG
                     GWHAIFLVNIPVVLVSICLGYFLFPKEVKEKKSIKETLKNVLSRLDIIGILLFSIAMI
                     FILLFLLSMKESFNLEQLVFGIILMCLFIWHELRTKLPFIDIKLFVSNPKLSKVYLQF
                     IILNFFNYILFFGLPSYFQDALHYSAKSTGLFMLFMSGIGIFISPLTGKWIDKSGTRF
                     PLVTSSIFMFISAVLLSVVFIHIPVIGKGIILSLAGISYGVGNVALQSSMFEESPRDS
                     IGTASGLFQTSRYLGSILATVLLGMVFEVNITSEQFQILGYVMVVLGTISFLLNFILK
                     KELRKVE"
BASE COUNT         8755 a         2387 c         3913 g         7050 t
ORIGIN      
        1 aaaaagtact ggatataaag gtatagtgta tataaataac tataaaatta ttgataaaaa
       61 taaactttac tctttaatag gggaaataaa gttttatatt agtaaaactt ataggtactt
      121 atataagaaa aactcagatt ttataaattc tatactatta gcagaagttg aaaatttgac
      181 tgaggaacaa aaagaaattt ttaccagaac tggaactagt catgtaatat ctatatcagg
      241 tcttcataca ggaatattat gtgtaattat atcctttcta ttaagaggta taaataaatt
      301 gtataaatta ttaatactgt cgatttttat aactttatat tgtataatgg taggtgcgtc
      361 tccatccata attaggtcta tagcatttgt tatgattttt tatttatcaa tatttattga
      421 tagaaagaaa gatggaatat cggcattgtc tctaattggg ataattttaa ttatgaataa
      481 cccctatgtt atatataatg taagttttca attgtctttt ttagctacac tttctatatt
      541 aatattctat aataaaataa atagtattat aaaattaagt atggtatcat tgacaatatc
      601 atcaaatata ttaactttac ctataattta ttatacattt aaaggtatac cattgctttc
      661 aattatagga aatttaatta tagtgccatt tgtgggagta ataatgtatt taagtattgc
      721 aagtttaatc gtatttaaag taagtgtagt aatagctaaa attatatctt tttttaatag
      781 tacatttata gaaagcatat tttttttact agaaaaaatc agcaatttaa gttttgcata
      841 cattaatata gaaaatccta aattttatat tgttgttatt tattacatag gagtgttttt
      901 ttacatattt tacatagaag gaaaagagat aaaggagcaa gagaatgaat tacaaggata
      961 ttataaggaa tgtaaaagag aaaaactttg aaaaaatgta tcttttttat ggaagagagt
     1021 attatttaat tgagaatgca ataaaagcat ttaaagatag tctaaacgag ggaatgcttg
     1081 attttaattt agatataata gatgggaagg aaatagtctt aaatcagctt ataagctcta
     1141 tagaaacact tccatttatg gatgatagga agatagtaat aataaaagac tttgaactat
     1201 taaaaggaaa gaaaaagaat tttacagata gtgatgagaa atacttaata gagcatttag
     1261 acaatattcc agacaccaca actatagttt ttgttgtata tggagatgta gacaaaagaa
     1321 aatcattagt taagaaaata ggaaacaatg gaattgtttt tgattgtgat aagctttctg
     1381 atatggattt gtttaaatgg ataaaaaaat cttttgcttt aaatgatgtt ataatagata
     1441 attctcaaat catgtatttt attgaacaag aaggatacag agataagagt agtgaaaaga
     1501 cattatctga tttagaaaat gaaataaata aaataagttc atttgttggt aaagggaata
     1561 atgtaaccaa tgatgtaatt gataaattat ctcaaaaaaa agttgagaat gatatattca
     1621 aattaatcga ttatattgga gaacaaaatg cttctaatgc aatgaaaata ttaaatgata
     1681 tgatacaaga aggcgaatct gtattaggta tattttctat gatagcaaga caatttaaaa
     1741 taattatgca agtaagacag ttacaacttg atggatattc aacaaaactt atagctgata
     1801 aattaaaaat gcatcaattt gttgtaggaa aagcattaaa gcaaactaaa aatttttctg
     1861 atgatataat tgtggaaata ttaaactata tattagaaag tgattacaaa ataaagacag
     1921 gtcttataag agatacttta gcagttgaaa tgttggttag tagatactgt aaaagagaag
     1981 caatttaaaa aatctatata ttaataaaaa ataaatagca agatatgtta tagttcagag
     2041 tagatgtaag ctaaattaag tttgatatac aatcaactat aatatgtcta actatttatt
     2101 ttttattgta taaatttaca aaataaaaaa cccctacata ggggttatta tatataagaa
     2161 atataaactg gtaattaagc gttcataccg tttaattttt gagctaattt agctactttt
     2221 ctagctgcag cattcttatg tatagttcct ttagaagcta cttggtatat tcttttttga
     2281 gcgtattgga acttagcaac agcatcctct ctgtttccag ctgcaacagc atcttcgaat
     2341 cttcttattg cagtttttat ttgagatttt ctaactctat ttaaagcagt tttcttttcg
     2401 ataacactta ttcttttctt agctgatttt atatttgcca ccgtgttcac ctccctgtat
     2461 ttttttatca tattcatcgt caacatatta gattttaaca gaaataaatc taaaaatcaa
     2521 ggattattat ttatatattt taataatgtt ttttattttg attttttaga ctgtaaattg
     2581 tgtataaata atttgcaata tcttgttttt aaattggtat attttgtgtt ttaaatattt
     2641 tgacatatat aattaatatt tcattttgta acaaatattt gagataatac aaactattaa
     2701 catacatttt gatagtattt ccaataatta taagataata caagaaatta ctcatttttg
     2761 taaatttaat gaaaaattat aaaaatataa atttatatgc ttaattaaga taatttttcc
     2821 aataatcaag ataatttttt tcattagtat gtatgataga tgcatcaaac aatataacta
     2881 atatgttaga aggttatatg taattaatgt cagtgtttat atagaatagc atttgtagca
     2941 tttattatag ttgtaattac tatttatatc atagacttga atagtctaaa aaaatagact
     3001 ataatatttt tatagactaa agaaagggct gataagatgg acatagcaaa actaatttta
     3061 aatcctgcaa ggcttcgtat tttacaatat attcgacttt atggcagtgt tcgtacatct
     3121 gatattgtaa agtatttaaa tgatattcct cgtgcaacag tttatcacca tgtaaaaatt
     3181 ttagaagaga acaatatgat tgaagtaatt aaagaaaatc gtgtgcgtgg tactattgaa
     3241 aaggtttatg cactaaagga atatacaaca tctatggaag gagagacctt cgttgcactt
     3301 tctacagcat tttatgtagg tctgatgcag gaaatgaatg aatactttag cagaaaagag
     3361 caagaccata aaaaggataa tgtatttttc tcttcagcat tactatatat gagtgataat
     3421 gaatatgaaa atcttcttaa aagtatagct gatttattga aaccatatat agaacaaaaa
     3481 cctaaatcaa atctaaaact tagaaaactt tcaattatat cttctccacc tgtagctgat
     3541 aatgataaaa caaaataaca tgcaacccat ttttataaaa ggaggttata tatgaaattt
     3601 catgagtttg gaaataaaaa cagaccacat attatgttga ttcatggggg agggaatgca
     3661 tggtggaact atttgcgaca agcagaagtt ttgtctaaca aatatcatgt gatacttcct
     3721 acattggatg gtcatggaga agaatatgaa acaacataca tttctacaga ggatacagca
     3781 gataagttga tatcatatat agatgaaaat tgcagtggac atcttttcgc tttgtgtggg
     3841 gtatcacttg gtggtcaaat tgtcatggaa cttttatctc gaaaacctaa tattactaaa
     3901 aaagcaatta ttgatggtag tatttgctac ccaagacctc ttatggcaag gttttgtatt
     3961 gctggtattc gattttttgg aggacttttg tttagtgaga aggcttgtcg ctttcaaatt
     4021 gctatgatgc caaaattgtt acctgaaaat atgcaatatc cagatgaaat aaaagcgtat
     4081 tatatgacag atatgccaca tgtaagaaaa gaaacattct ataatatgta tcgtacttac
     4141 atgatgaact atacacttaa agagaatgtt aaaaaaacca cagcacaagt aatgtactgg
     4201 tatggagaaa aagaaatgaa gtgtgtcaaa aaatctgcaa aactgtttca gtcttatgtg
     4261 ccctcttgtg agatttatga agctaagagc tataatcatg ggtatttatc actttatctt
     4321 ccaaatgaat ggttggaaat tgcagaacca tttttccaaa aggaataaag gtgttaggtg
     4381 attattgtat aattattgct gtttttttat atagtaaata aattaggtat aaatataaaa
     4441 aattatttta gttaatatat tagtgaaagc ttaataggaa aattataaat agattaaagg
     4501 tagcacctat ataaatagtt gctacctttt tctgtttgta aataaatgat agataagaag
     4561 gtttactgac aaatcactga ctaaacccaa ttttcttaca ttgaaagcct taattttact
     4621 tgttttaaat aaatttacaa tttcttgtta taaaatacta aattttgtta acaattataa
     4681 ttagcattta atttatactg gaggtttata tgattagtgt aagaacagat ttagctttag
     4741 aagctagtga aatgtgtgaa aagtctcaag aaggaagtag tattcctggt gtaaaaatag
     4801 aaactaaaga attagaaaat tgcattgtaa ctaaagttga agtaatagac aggcaaggcg
     4861 cagagataat gaataaagat ataggaaagt atataactct ggaaagtaat cttatgaagt
     4921 ttgatgatga tgagtcaaga gaagaaatga taagttattt aaaagaggag ttagtagata
     4981 tatttggcca agacaaaaat aaaaaaaccc tggtaattgg tcttggaaat agaaatatta
     5041 cttctgatgc gttaggacca aagagtgtat caaaaacact tgtaactaga catcttttta
     5101 aaaattataa taaagactat gatgatgatt tcactgaggt atcagcttta agcccaggag
     5161 ttatgggtgt tactggaata gaaactagtg aaatagtaaa atcattggtt gagaaggtta
     5221 agccagatag agtagtagca atagatgcat tggcttcaag aaaaatggag agagtaaact
     5281 ctactataca gatatcaaca gcaggaatat cacctggtgg aggtgttggc aatactagaa
     5341 aatctctaac taaagaaact ttaggcgtgg atgttattgc aataggcgtt ccaacggtgg
     5401 ttgatgcagc aactcttaca atagatgtct tagatatggc aatagacaat ttaatagctc
     5461 aatcagaaga aacagaaagt ttttatgaaa tgttgaaaaa acttaaagaa gaagaaaaat
     5521 atcatctaat aaaagattcg ttagacccat atgacaagaa cttaatagta acaccaaagg
     5581 atatagatga tacaatcgaa aatctatcta taataataag tgaaggctta aataggtctt
     5641 tacatccagg tagattggta taaaataagg aggagcaatt atgtttaaaa aatgcattaa
     5701 agtagtaacc ttgactttta tattagtatg cattttacca ggaaaatcat tagctttgaa
     5761 tcaagatgat tttttaaagt ttttagtaaa ttcatcttat ccagaagcta aagtcgaagg
     5821 aaatgataca gaaaataaaa agaataataa aaataaagaa acaagtaagg aaaataagga
     5881 agaaagtaaa gaaggaaaca ctaaatctaa agatgcaagt aaagttgata ataaaaaaga
     5941 gagtgaaaaa gaatatataa aactttatgt tggtaaagaa aatgttccag atattgagtc
     6001 aaaaaattca gacacaactg aaactaacac aacatctagt tcagattata aggatgattt
     6061 aagagtaacc aaagaaaatc caagaatttt gatatatcat actcatggat gtgagactta
     6121 ttcaaattca cctgatggaa attatcattc aagagataag aaaaattcag taatggaagt
     6181 aggaagtgca ttaactagtg ctttagatag caaaggatgg ggtgtagtcc atactactaa
     6241 ataccatgac tatccatctt ataataactc ttatgcaagt agcttaaaaa caatacaaag
     6301 tatattacct aaatataact cagtggatat agcgatagac ttacatagag atgctaggga
     6361 tttaactaat ccagccacta aggaaaaaga ccatttaaaa tatacaacta tgataaatgg
     6421 agagagagta tcaaagttct tctttgttgt aggaggtaaa aatacaaata gaaaacaact
     6481 tagagcttta gcagaagata taactgcttt tgctgagaaa aagtatcctg gtctagtatc
     6541 tccaatagta gaaaaagact atgctagatt caatcagttt gcagttaaga atcatatgtt
     6601 agtagaaata gggaataacg caacaagtgt agaagaatct aaggctacta caaagtattt
     6661 agccgagatt ttggatgaat attttaaaca aaaaaattag agctttaagt tataattagg
     6721 agcatgctaa atgagccgat tagaaaaaaa tatagaaagt aaaagtaaac taagaaaata
     6781 caagtatatt atgagaatct tatttttgat tactatgatt atatgtacat cagtttgtgt
     6841 atttatagtg gacagtaatg caaaaagtat gctaggaatg aaacaatatg attttccaag
     6901 tattaaattt gatataacaa aatttgattt tgacatacca aattttgata tacatgaaat
     6961 cataaaaaaa tttaataagt agtaataagt gaataaggtt tattgattaa aataagcctt
     7021 attttagtta tatattttta atgtataaaa taaaaattca ttaactgtat tttataggat
     7081 ttactttaag tttatgatat tatataatat ttagtgttag acttgataat ccacatataa
     7141 tgtggataat tttgtttagt gccaattagt ttatattcaa aaattttaaa tttggtatat
     7201 aaagagtttt tagataatgt aaaataataa ctataagaat aatcaagagg agggaatttt
     7261 aaggtggaca ataaacaaag tagaactaga aattttagta taattgcaca tatagaccat
     7321 ggaaagtcta ccttagctga tagattaata caacaaactg ggcttgttag tgaaagagac
     7381 atgaaaagtc aattacttga caatatggac cttgaaagag aaagaggaat cactataaag
     7441 cttcaaaaca taagattaat gtataaagcg aaggatggaa atgaatatta tttaaatctt
     7501 atagatacac ctggacatgt agactttaac tatgaggtat caagaagttt agctgcatgt
     7561 gaaggagcac tattagtagt tgatgcagct caaggtgttg aggcacaaac tttagccaat
     7621 gtttatcttg ctatagacca agatttagaa atattaccaa taataaataa aatagattta
     7681 ccaagtgcaa gaccagagga agtaaaaaat gaaatagaag atttaatagg gcttgattca
     7741 agtgaagctc ctcttatttc agctaaaact ggtttaaaca tagaagatgt tttagaagat
     7801 attgtaaaaa atgttcctcc acctaaagga gataatgaag ctccattaaa ggcattaata
     7861 ttcgattctt actatgatgc ttacaaaggt gttgtagctt atgttagagt atttgaagga
     7921 actgttaaaa agggtatgac aataaaaatg atgaatacca ataaaaagtt tgaggtaact
     7981 gaagttggtg ttatggctcc aggtcaaact gaacttagtg aattatcagc aggtgatgtt
     8041 ggttatattg ctgctagtat aaaagatata agaagttgtc gtgttggtga tacaataaca
     8101 gattcaaata atcctacaga agaaccttta ccaggataca aaaaagctac tccaatggta
     8161 tattgtggta tatatccagg agaaggagaa aagtatgaga atgttagaga tgctcttgaa
     8221 aagcttcaag taaatgatgc tgcacttgaa tatgaagctg agacttcagc agcactagga
     8281 tttggtttta gatgtggttt cttaggtctt ttacatatgg agataatgca agaaagactt
     8341 gagagagaat ttaaccttga tataattact acagctccat ctgttatata tagagttaca
     8401 aaaatggatg gagaggttgt aatgatacaa aatcctgcaa acttaccaga accatctgag
     8461 ataaagatga tagaagagcc tatagtaaaa ggagatataa tagttcctaa agactatgtg
     8521 ggtgttgtta tggagctttg ccaggaaaga cgtggaaata tgttaaatat ggaatatata
     8581 gatgatagaa gagtaatgct tcactatgac cttcctctca atgaagttgt ttacgatttc
     8641 tttgatgctt taaaatcaag aactagaggt tatggttctc ttgattatga ggttaaaggt
     8701 tatgtagcat ctacacttgt aaaacttgat atattaatca ataaagagca agtggatgca
     8761 cttagtttta ttgtccatga gacacgtgct ttccctagag gaaaggcaat gtgtgagaaa
     8821 ttaaaaggag aaattccaag acatcagttt gctataccaa tacaagctgc tgttggtaat
     8881 aaggttattg caagagaaac aataagcgct ctaagaaaag atgttcttgc taaatgttat
     8941 ggtggagata tatctcgtaa gaagaaactt cttgaaaaac aaaaagaagg taagaagcgt
     9001 atgagacaaa ttggttctgt tgaagttcct caaaaagcat ttatgtctgt gcttaaatta
     9061 gatgagtaaa tccttataaa tttagataaa gatatttaaa agctagagtg attttagaat
     9121 tatttctaaa ttagtctagc ttttttatgg tatattttaa gtaaactcat agagaatata
     9181 agtaagaata ttaaagaaga ataaaaaggt gatatttatg attaatatag aaattcctaa
     9241 aaaagtagac tatataatta aagaattaga aaagaatggt tatgaagctt atatagttgg
     9301 aggatgtgtt agagattgtt tattagaaag agttccaaac gattgggata taacaactag
     9361 tgctagacca gaagtggtag tagaattatt tgaaaaaaca attccaactg gtatacaaca
     9421 tgggactgta acagttatga ttgaacatga accatttgaa gtgacgactt atagaattga
     9481 tggaaattat agtgatggta gacatccaga ttcaatagaa tttacaaata acatagttaa
     9541 ggacttgtca agaagagatt ttactatcaa ttcaattgca tacaattcaa agacaggatt
     9601 agtcgaccca tttaatggct atgaagatat acaaaataag tatatacgtt gtgttggaaa
     9661 tccagtagat agatttgaag aagatgcact tagaatgctt agagcagtta gattttcagc
     9721 acaactcaat tttaaaatag ctgaaggtac taagcaaagt attcataaaa aagcagattt
     9781 gataaaaaat gtttctattg aaagaatcca gacagagttt aataaaatat tagtatctga
     9841 ttcatctaaa ttaaacttat taaaatcaac aggtttgttg aaatttataa ttcctgaaat
     9901 atgtgaatta gaagatgtta ctcaacacaa tccatatcac atctatgatg tacaaaaaca
     9961 tactttaata gctacagaag taattgaaga tgaactgtat ttaaaactta caatgttgtt
    10021 tcatgattta ggtaaaaaag taactaaaac aactgataaa aatggtgttg accattttta
    10081 tactcatagt agagaatctg taaagattgc aaagaagatt ttgaaaagac ttaagtatga
    10141 taattatact attaataaag ttttaatatt aatacaatat catgattata gaatagaacc
    10201 taaaaggaag ataattaaaa agttattaaa taaacttgaa gatgttgaat tatttgaaga
    10261 tttaataaaa gttaattggg ctgatacact tgcaaaaaat ccaaagtatg caaaacaaaa
    10321 gatattaaat cttattgagt gtgaaaaaga atttaaacat ataataaatc aaaaggagtg
    10381 ctttaatctt aaagatttag ctattaatgg aaaagatttg atatctatag gtataaaacc
    10441 aggtaaagat ataggatata ttttaaataa gatgcttgaa atagtcataa ataatccaga
    10501 gttaaatgaa aaagaaatac taaaagaaaa agcattaaat atatatacat tttagattca
    10561 aatataaaaa atttaattac tttaaaaaac atagaataaa atacttattt agataaaata
    10621 aataattttt agagaatatt ttagaagtta cgattgtatg atttttaaat gcataggcat
    10681 ttactctagg actatagact aatataaaaa aaaactttgg gaatactaaa accataaatt
    10741 tataaaatta atattttata tactgtaaaa cagtgaggag ggacagtatg catactcaac
    10801 tacaaaagac tattggtctt tcagcagctc tttctactgt tgtaggtatg gttataggtt
    10861 cgggagtttt ttttaagcca caagcaatat acactacaac taatggagct ccaggtctag
    10921 gtattatagc gtggctttta ggtggtttta taacaataac tgctgggctt acagctacag
    10981 aaatttcagc tgctatacca aaaactggtg gtatgatgat ttatatcgaa gaaatatatg
    11041 gagaaaagtt aggtttttta actggatgga tgcaaactgt attatttttc ccaggtacat
    11101 cagcggcatt aggagtaata tttgctcaac aagcatctga acttttagga atgagcccaa
    11161 ataatatggc aaatgtactt cctatagcaa ttggagttat actattttta gcgttattaa
    11221 atataatagg ttcatcctta ggaggaaaag ttcagacagt agccactatt ggaaagatga
    11281 tacctttaat tttaataata gtctttggat ttattaaagg tcaaagtagt gaagtattaa
    11341 atccatttgt aggagatggt gtaaatgcat caaatgcact tggacaagta ttaatagcta
    11401 ctttgtttgc atatgatggt tggataaatg ttggagctat atcaggagaa atgaagtctc
    11461 cagagaaaga tttaccaaga gcaatagttg gtggtttatc attagttatg gcagtttata
    11521 ttataataaa tatagcttat ctttgggtag taccagcaag tgaattagca acagttactt
    11581 ccccagctac attagtagca acaagattgt ttggaaatat aggtggaaaa gtaataactg
    11641 tgggtatatt aatatcagta tttgggacat tgaatggata tttattaaca ggttcaagga
    11701 taccttatac attagctgaa atgggaactt taccagcatc taaaactctt ttaaaagtaa
    11761 attctggagg ttctcctgta aattcaatac tacttataac tgtgttagcc tgtgtatatg
    11821 cattatctgg tcaatttaat cttttgacag acttaacaat attttcaata tgggtatttt
    11881 atgtattgac ttttataggt gttatgaggc ttagaagaca aaagccagat ttacacagac
    11941 catataaagt ccctttatat ccaataatac caattatagc tatattaggt ggactgtttg
    12001 taataataaa tcaaatattg acttcaacag tcatatcttt aggcggaata tttataacac
    12061 tattaggttt accagtttat tattatatga aaaaaagata actacttaat ttaagttaga
    12121 taaatttggg taaaggtgaa aattaacttt tatccaaatt ttttatactg ttatacaata
    12181 taagtattat atattgcttg atgtgctatt ttgtttgatt tataatttag taattgatgt
    12241 tttaagataa tttaagaaat gaggagtgaa agatgctagg actttatgta catattccat
    12301 tttgtgtgaa aaaatgtaag tattgtgatt ttaattctta taaaatggac atagattcaa
    12361 aaaaaagata tatagaagac ttaaaaatag aaatggaatt atatagtaat aaattatata
    12421 aagataataa atataaaaat aaagaatgct gtagtctaaa taaaaatgac aaaataacga
    12481 gtatatttgt agggggaggt acacctagta tactaacctc tgatgaaata agagaagtat
    12541 ttataagtat aaaagaaatg tttgatatag atgagaatgc agaaataact atagagtgta
    12601 atcctgggac attaacatta gaaaaattaa aaactatgaa agagattggc ataaatagac
    12661 ttagtatagg gctacaagct attcaagaaa agcatttgaa ctttatagga agaatacata
    12721 cttatgaaga atttgagaaa aactataaag atgcattaag tgtaggtttt aaaaatatta
    12781 atatagattt aatgtacagt cttccaaatc aaactctatg tgattggaag gaaactcttg
    12841 aaaaagttgt acacttaaat ccaacacata tatcagctta ttcccttata ctagaagaag
    12901 gaactgaact atacaatatg tatgaaagta ataaatttga acttatagat gaaaatgtag
    12961 atatagaaat gtatgagtat acaataaact acttaaagtc aaaaggatat aatcaatatg
    13021 aaatatccaa ctactcaaaa gaaggctata attgtgagca taatatttta tattgggaat
    13081 gtgaacatta tatagggatt ggagcaggag cttctggcta tattaatgag aacagataca
    13141 ataatgtaga atctttagaa gattatcatt taagtttggt aaaaagagaa aaaccaatac
    13201 aagaaaatga aattctttct gagaaagata tgatagaaga aaagatattt atggggctta
    13261 gaatgaataa aggcataaaa tttgaagatt ttaaaaaaaa atttggaata gattttagag
    13321 agaagtataa taagcaaata gaaatgctat tagctagaaa gcttataaat cagagctttg
    13381 aaggtataca attaactcaa aaaggaagag aaatatctaa tagtgtattt atagaattta
    13441 tggaataatt tttaaggtgt tgacaaaata aatttataat ggtatataat atatataatc
    13501 tttttagcac tcgaacttag tgagtgctaa cagctaggag gtataataat atggaattaa
    13561 atgaaagaaa attaaatatc ctcaaagcta tagttaaaga ttatatagaa acagctgaag
    13621 ctataggttc tagaacaata tctaaaagac atgatttagg tgttagtgct gctaccataa
    13681 gaaatgaaat ggctgacctt gaagaattag ggtatttaat tcagcctcat acttctgcgg
    13741 gtagagttcc atctgaaaaa ggctataagt tatatgtaaa ctctcttatg agtaaaagcg
    13801 aattggatga taatgataag attcttattg aacaatgtat gaatcacaat ataaatcata
    13861 taaaagaatt gattcatgaa acttctaagc tattatcgca actaacaaac tatacaactg
    13921 tagcagttac taagagttta ataaatcaaa gtgttataaa gcacatacag ttggttgcta
    13981 tgaatgacaa taatatttta cttatagttg taacagataa aggggactta aaaaaagcta
    14041 accttacaac taatgtatat ttagatcaat ctaagttaaa tttgatttct gataatctta
    14101 caaggaagct cttaggtaaa agtataacag atttggatga taatctaatt gcttttatta
    14161 aatacgaaat aagtgagtat tctgggctta tagatgagct tttaaatgct ttgaactcaa
    14221 atatgaaaga agaagatttt tctctatcat taaatggagc tactaacata tttagttatc
    14281 cagaatttaa tgatgtatta aaagcaaagt catttttaaa tatgttggaa aaaaaggaaa
    14341 caatagctga cataattaaa tcaaagggaa tacaaaaaga caatctaaat ataataattg
    14401 gtagtgataa tgattgtgaa ctggcacagg attgtagtat agttacagca acttataatg
    14461 tagatagaga cttggttggg cgaataagct ttataggccc taccagaatg gattatgcta
    14521 gaatttactc tataataaat tatatgagtt tattaattaa tagaaagtaa agaaatttta
    14581 aattgcgagg tgtaaagtct tggataaaaa aaatgagcaa caggaagtaa gagaagaaaa
    14641 tgatacttct attaaccaag aatcggaaac tcaagtagag ttagaagagg aagttgttaa
    14701 tgaagaatgt gaaacatcaa gtgaaaaaac tgatgaaaaa gaagttgatg atgaaaatgt
    14761 aacagatata aattctaagt tagcagaaaa aaaattgcag gatgagttgg atgaattaaa
    14821 tgataaatat caaagacttc aagccgaata tgcaaactac agaagaagaa ctcaacaaga
    14881 gaaagagaca ataggcgtat ttgcaaatga aaaaataata actgaattga taccagttat
    14941 agatagtatg gaaagagcct tagatgcatg tgaagataag gaagatacta tgtataaggg
    15001 tataagcctt gtacataaac aattaataga cactttagta aaatttggag tagaagaaat
    15061 agaagcagaa tctaaggaat ttgaccctaa tctacatcta gcagttatgc aagaaagtgt
    15121 agatggagtt gaagcaaatc aaatagtaat ggtacttcaa aaaggatata agctaggaac
    15181 taaagttgta agaccttcaa tggttaaagt ttcttgctaa gtataaatta aaggttaaat
    15241 tatttaacct aatataaaat attaaaataa gtaaaactta attatataat tactcgagga
    15301 ggattttagt catgggaaaa ataataggaa tagatttagg aacaacaaat tcatgtgttg
    15361 cagtgttaga aggtggagaa gcacaaataa tagcaaatag tgaaggtatg agaactactc
    15421 catcagtagt agcatttaca aaagatggtg aaagaatagt tggagaacct gcaaaaagac
    15481 aagcagttac aaatgcagat aaaacaataa cttctataaa aactcatatg ggaactgatt
    15541 ataaagtaaa tatagatgga aaatcatata ctccacaaga aatatcagca ataatattac
    15601 aaaaattaaa atcagatgca gaaagttact taggacaaac agtaacagaa gcagttataa
    15661 cagtaccagc ttactttaca gatgctcaaa gacaagcaac taaagatgct ggtagaatag
    15721 cagggcttga tgttaagaga ataataaatg agccaacagc agcagctctt gcttatggta
    15781 tggataaatt agaccaagaa aagaaaatat tagtatttga cttaggtgga ggaacttttg
    15841 acgtatctat acttgaaata ggagatggaa cttttgaagt tttagctaca gctggtaaca
    15901 atagattagg tggagatgac tttgaccaaa tagtaataga ttatttagca gaggaattta
    15961 aaaaagctga aggtgtagat ttaagaaatg ataaaatggc tcttcaaaga ttaaaagaag
    16021 cagcagaaaa ggctaagaaa gaattatcat caacaatgag ttcaaacata aacttacctt
    16081 tcataactgc tacagcagaa ggaccaaaac acttaaatat agatttatca agagctaaat
    16141 ttgaagaatt aactagaggt ttagttgaaa aaactatgga accaactaag acagctttac
    16201 aagatgcagg actttctaca ggtgatatag atgatgtatt attagtaggt ggttctacaa
    16261 gaataccagc agtacaagaa gctgttaaga agtttatagg aaaagaacct cataaaggta
    16321 taaacccaga tgagtgtgtt gcagcaggtg cttctataca agctggagtt ttagcagggg
    16381 atgttaaaga cttattatta ctagatgtta ctccattatc tcttggtata gaaactatgg
    16441 gtaatgtaat gactaagata atagaaagaa atactacaat accaactaag aagtctcaaa
    16501 tattctcaac tgctgctgat aaccaaacag ctgttgatat acatgttctt caaggtgaaa
    16561 gaagtatggc ttatgacaat acaactttag gaagattcca attaacagat ataccaccag
    16621 cacaaagagg aatacctcaa atagaagtta cttttgatat agatgcaaat ggtatagtta
    16681 atgtttcagc taaagattta ggtacaggaa aagagcaaaa aataactata acatcaaaca
    16741 ctaatttatc agaatcagaa atagagcaaa agataaaaga agcagaaatg aatgcagaag
    16801 ctgacaaaca aaagaaagaa aaaatagaag cattcaatca agctgaatct actatatatc
    16861 aaactgaaaa aactttaaat gaacttggag ataaaataag ttcaggtgaa aaagaggata
    16921 tagaaaaagc tatagcagac ttaaaagctg taaaagataa tcaagatgct acagcagaag
    16981 aacttaagaa agctacagat gaagtaatga ctaagttcca aaaagtatct caagaaatgt
    17041 accaaaaagc agctcaagaa caacaagcgg cacaaggtgc agaacaagca caagacaatg
    17101 gacctaaaga tgacaatgta gtagatgctg actttaaaga agtagatgaa gataaataag
    17161 ctatataata tgtaacacta aatgataatt ggaacatata tgatttgtga aaatcatata
    17221 gatgttaaag atatatggac aatatacatc ataaagaata taatatatca tagattatat
    17281 aacttaaagt agaatataag aattaatgat agcttgtagt ttattattct acaagctatc
    17341 gttttgtaaa atgaaggtgg tgtcaatttt tgagtacaaa aagggattat tatgaagtct
    17401 taggtatcag taaaggtgca gaagctcaag agataaaaaa agcttataga aaattagcaa
    17461 tgaagtacca tccagataga aatcctggag ataaagaggc ggaagaaaaa tttaaagaga
    17521 taaatgaagc ttatgaagtt ctatctgatg atacaaagag aaaaacttat gaccagtttg
    17581 gacatgatgg gctaaatggt caaggcggtt ttggtggtca aggaggattt ggcggtcaag
    17641 gctttggtgg ttttgaagat atgttcggag atatatttgg tgacatgttt ggaggaagct
    17701 tcggaggtgg aagagcaaga agaagagggc ctcaacgtgg tgcagatata agacagagtg
    17761 ttactatatc ttttgaagaa gctgcatttg gtaaaaagat gtctataaaa gtaaatagaa
    17821 gtgaagaatg tgaagaatgt aatggaactg gagcaaaacc aggaacatca aagaaaactt
    17881 gttcaacttg taatggaact ggtcaagtta gaactgttca aagaactcca tttggtaata
    17941 tagcaagttc aagaccatgt agtgcttgta atggaactgg agaagtgatt gaatctccat
    18001 gtagtaaatg tcatggaact ggaaatacaa gaaaagttaa gactatagaa gtagatatac
    18061 ctgctggtat agatgatggt caaatgataa aactttctgg tcaaggtgaa gtaggagaaa
    18121 aaggtgctcc aagaggagac ttatatattg tagttaatgt taagtcacat ccactattta
    18181 ctagagatgg aaatgatatt tattttgaaa tgccaattac atttgttcaa gcaactttag
    18241 gtgatgagat agaagtacct actttggatg gaaaagttaa atatagtgtg ccagagggga
    18301 cacaaactgg aactgtattt agacttaaag agaaaggaat ccctagaatt agaggtaatt
    18361 caagaggaga ccaatatgtt aaggttgtag ttgaaattcc taaaaaatta aacgataagc
    18421 aaaaagaact attgagagaa tttgcgaagg agtgtgggtc gaacgtccac gaaaagaaga
    18481 aaaccttcgg acaaaagata gaagatatgt ttaagaaaaa gtagttaaag tagccaatat
    18541 ataatcatat ttttaaaatc ttagttattt ataagattgt caaaggagat attatgattt
    18601 ttatattggc tatttttgta taaaaaataa atgtgcataa aataaaactg aatataaata
    18661 attttctgaa aaatacttgt cctaaaatat ataatatgct ataatataat caaataaaag
    18721 aaaggggtga ttccagtggg aacggatgtg gcactgccaa atgatgaaga aaactttatt
    18781 gtaatataca aaataaaatt agatactttt agtgctagat taagtactgg aaaaactcat
    18841 gagctgggat aattattgta attacctaga ctcaaacttt tagtagtaaa atagtaatat
    18901 tatatagaca aggtatctaa tttttaaatc ttttgtatga attaaaattt ttataaaggg
    18961 tatatctgat tagaatgtaa ttagggaaac ctagttgtga attactttta gtatatacat
    19021 gtgtaaagaa atatgtatat ggtattgggt attgtgctag atgtgtatgt aaaggaatat
    19081 gtgtctagtt gggtatatgt aaagaaatat acttataatc tatgaaaaat ttttagtata
    19141 aattgctaaa acattgagat tgttttttat agaaagttag tttataccaa ctaaaaatgt
    19201 gcttaagatt tgtttgatgt ttaattataa ataaggttgt agataaaaaa ataagtaaag
    19261 acaaaggttt aaaatacttg ctttaaatat agtttgtttt gaacacttgc caaattaaaa
    19321 taattaataa aatagacatc ttctcatagt aaaatatact gtgagaggat gtttttgctt
    19381 tgttcataaa cttttatgaa aaatttgcat agtgtcacat tttaatatac tatatatata
    19441 ataaaatata gataaaatta aatgattcaa aagagaaagg tgaaaagaga tgtattatat
    19501 aggtgtagac ataggaggaa caggtataca agcaggagta gttgataact atgggaagat
    19561 aatttttagg tcagagtgta aaacagtaat tgaaaaagga tttgaaggaa tacttaatga
    19621 cataaaaata atgatttata agttgttgga agataataaa cttactatga gtgacataaa
    19681 atctattgga tttggtgttc caggttttat aaataaagaa ggattagtaa cttgtgtaaa
    19741 tttaaaatgg aataaaaaag cttttaataa agagttaaaa aaaagatttc cagatgttga
    19801 aattcatgga gaaaatgatg caacagtagc agcacttgga gaagcaaagt ttggaagtat
    19861 gaaaggtgct aatgttggag tattatatac tttaggaact ggtgtaggtg gaggaatagt
    19921 aattaatcaa aaagtctttt ctggagcaca tggattgggt tcagaaatag gtcatcaaat
    19981 tataggagaa aactatttta attgtaattg tggaaataat ggttgtgtag aaactttttg
    20041 ttcagcaact gcaattataa agtattctca aaaactgata gaagaaggag aaaagagtag
    20101 gattttagat ttggcagagg gaaatttaga aaatgtaaat gcaaagatgg tgtttgatgc
    20161 atatagagaa aatgatttag tggcaattaa agtaataaat agatttaaag agtatttagc
    20221 aaaaactttt gcaaacacaa taaattcttt agacccagaa attatatcta taggaggagg
    20281 catttctaaa tctagcgata taatacttga tggaatagaa ggtttggtaa gaaaatttgt
    20341 attatacaaa acagaagata tagctacaat tacatgtgca actttaggtt cagacgcagg
    20401 aattatagga gcagcttttt tataatgtaa atgaactgct tattggaggc gtgatgatat
    20461 atgggtaaaa caaatgctag aagaacgctt tttttgatag caataggttc aggaactatg
    20521 ctgaatcctc ttaattcttc tatgatttca cttgctttac atagtataca aaatgatttt
    20581 catattagtt ttacaactgt atcttggatt gtttcagcat tttacctagc tagtgctatt
    20641 gcacaaccag tttcaggtaa gataggagat ttaataggta gaaaggtctt atttttgagt
    20701 ggtttgatgc ttgtaatttt atcagcatcc atagtaccac ttgttcaatc attctttata
    20761 ttgattttta taagagtaat tcaagcaatt ggaacaagta ccctatatcc atctggagtt
    20821 gctcttatac aaaataatat aaaagaaaga caatcttctg cattagcagt tctaaccatt
    20881 tttgcttcaa ctacagcagg attaggtccg acacttggag gattattgtt ggacttagga
    20941 ggatggcatg ctatatttct tgtaaatata cctgttgttt tggtttctat atgcttaggg
    21001 tattttttat tcccaaaaga agtaaaagaa aagaaatcta taaaagaaac tttaaaaaat
    21061 gttttgtcaa gattagatat tattggcata cttctatttt caattgcaat gatttttata
    21121 ttactatttt tgctatctat gaaggaatct tttaacttag aacaacttgt atttggtata
    21181 atactgatgt gtctttttat ttggcatgaa ttgagaacaa aattgccatt tatagatatt
    21241 aagctttttg taagtaatcc taaattgtca aaagtttact tgcaatttat tatattaaat
    21301 ttctttaatt atattttgtt ttttggtctt cctagttatt ttcaagatgc cttacattat
    21361 agtgcaaagt cgactggatt atttatgcta tttatgtctg gtataggtat atttatatct
    21421 ccattaactg gaaaatggat agataaatct ggaactagat ttcctcttgt tacatcatca
    21481 atctttatgt ttattagtgc agtacttctt tcagtagttt ttatccatat acctgtaata
    21541 ggaaagggta ttatattatc attagcaggt attagttatg gagttggtaa tgtagccctg
    21601 caatcctcta tgtttgaaga aagtcctcgt gacagtatag ggacagcttc tggtctgttt
    21661 caaactagtc gttatttagg ttctatttta gcaactgttt tacttggaat ggtatttgaa
    21721 gtaaatataa catcagaaca atttcagata ttaggttatg ttatggtggt cttaggtaca
    21781 ataagttttt tattaaattt tatattaaag aaagaattaa gaaaagtaga atagtggatt
    21841 tatggattta ataagtctaa taactgataa gtttaaaaat attgtttgta aaacataact
    21901 ggtttgatat ttattaattc taagttttga agcatagagt actcgataag tatacaatat
    21961 tttgaattaa aattaagcag aaatttgaac tagtctttca aatctctgct taatttagta
    22021 gttaaatttt tttatagaga aaataagatt tgacacttag ataaaaaatc attgcatttt
    22081 caaaattctt taaatcaaac ccaag
//
LOCUS       DAJMZY010000066        22029 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.066, whole genome shotgun sequence.
ACCESSION   DAJMZY010000066 DAJMZY010000000
VERSION     DAJMZY010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 22029)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22029)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22029
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.066"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            69..251
                     /locus_tag="OE968_002401"
     CDS             69..251
                     /locus_tag="OE968_002401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219678.1"
                     /translation="MKKFRKHKSISNCISILLILYLTLGSLLPNNIYAQDLQSYSGKV
                     CNTTYKAPIERSEGFF"
     gene            587..2154
                     /locus_tag="OE968_002402"
                     /pseudo
     CDS             587..2154
                     /locus_tag="OE968_002402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021426623.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iota toxin protein Ib"
     gene            complement(2806..3807)
                     /gene="trpS"
                     /locus_tag="OE968_002403"
     CDS             complement(2806..3807)
                     /gene="trpS"
                     /locus_tag="OE968_002403"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HCP7219679.1"
                     /translation="MSEKKVILSGAQPSGKMTLGNYLGAIKNWTELQDNYDCYYSIVD
                     LHAITVPQDPKVLRANTIELLAQYIACGLDPEKNTIFIQSHVKEHVELMWVLNTMTYM
                     GELSRMTQFKDKSQKSEANLNAGLFTYPVLMAADILLYQTDLVPVGDDQKQHLELARD
                     LANRFNNRFSPTFVVPEGYYPKGGARVMSLQEPTKKMSKSDSNENAFILLADDSDSIK
                     RKIKRSVTDSLGVVKYNDEQPGIKNLIDIYSNLSKKSVEEIVNMYEGKGYGIFKEDVA
                     EVVSEALRPIREKYVDLLNNKDYLEKIYSMGAEKAEKQARKTLRKVYKKVGFIERRY"
     gene            complement(3830..4528)
                     /locus_tag="OE968_002404"
     CDS             complement(3830..4528)
                     /locus_tag="OE968_002404"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HCP7219680.1"
                     /translation="MNVIGIIGAMDEEVSILVDLMDIRETIKKASLEFYKGILEGKNV
                     VLVKCGIGKVNSALCAQILISEFKVDAIVNTGVAGALNEKLDVNDIVISTDAIQYDVD
                     TTAFGDPKGVIPRMKTSVFKADERLIDAAYKSSVEEVKTHKVLKGRVVTGDKFINSKE
                     LKEELVNDFGGYCGEMEGGAIAHVCYLNNTPFVIIRAMSDKADGSADVTYDVFVHDAA
                     NNSKDIVLNMLKSI"
     misc_binding    complement(4571..4811)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(4902..6305)
                     /locus_tag="OE968_002405"
     CDS             complement(4902..6305)
                     /locus_tag="OE968_002405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCP7219681.1"
                     /translation="MEKKKIGLWSLVFMNVSALYGIRWIAKSTASSFGLGLGAIPMWL
                     LFSFIYFVPGALICAELASTYQKGDGGLYDWVKEAFGEKYGFLVSWLNWTAKIFWYSS
                     FLTFLAVNVSYTIGNPALADNKMFVLILSLIIFWALSLIATKGISFTKIFTNTGALGS
                     TIPSAILIIFSFVAVFVLKKHDIASTYTIASMTPKLNMDAFVAISAIMFGLAGAETAA
                     NFITEIDKPEKNFPKAILISAGIVASLYVLGSIAITMIIPPDQITASKGVLDALSAVC
                     ASLGIGSWLVQLIAFGIAFSVLGAIVLYIASPIKMLFGSVKKGIFPDSLVEVNEHKIP
                     SKAVILQAIIVTIILLVTTLMPSVDAIYNVLVTMTALTALFPYVLLYASYIKLRKERP
                     DEIRPYTMAKSTSTCLGLAKMVLVVTVVGILLSAAPVMPTFAENVIYEIEMIGGGLLV
                     ILSGLWLWNRYEKKTAK"
     gene            6802..7878
                     /locus_tag="OE968_002406"
     CDS             6802..7878
                     /locus_tag="OE968_002406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HCP7219682.1"
                     /translation="MKAQRLNAVLEQMKKDDISQMLVSDPTSIFYLTGVLIHPGERLL
                     ALYLNLNGNNKLFINELFPVSEDLGVEMVWFNDTQNPVEIITEHIDKNATMGVDKNWP
                     ARFLLNLIELGGGSKFVNSSYIIDTLRMCKDEEEKELMRIASKLNDKAMEQLKATVSG
                     ELTEKQLVGKLSKIYEDLGTDGFSFDPIIGFGPNGANPHGEPGNALVKPGDAIILDIG
                     CIKDNYCADMTRTVFYKEIPEKGREIFEIVLEANKRAEAIVKPGVRFCDIDAAARDYI
                     TEKGYGQYFTHRTGHSIGLEVHDKGDVSSINTDTVQPGMIFSIEPGIYLPGEFGVRIE
                     DLVLVTEDGCEILNKHDKEICVVG"
     gene            complement(7995..8837)
                     /locus_tag="OE968_002407"
     CDS             complement(7995..8837)
                     /locus_tag="OE968_002407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HCP7219683.1"
                     /translation="MDKIKLIVDSACDLPDDIIEKYNIEVVGLNVSFGEESYISGKEI
                     DNETFYRKMSESKVLPKTSCPSPDKFLEAYHCQEESVLVINISSGLSGTYNSALLAKD
                     MFEKEGNNKKVEVIDSLSGSIGIGQLVLKAAILIKEGKEIEEIVSIINKYKDNPPFFG
                     TLETLENAIKGGRINPIAGKIINTLNFKAIIQVADGVVTPIDKARGEGNSLKKLITLV
                     ESKIKDKEEKVLFIGHANCPEKAQKVREVMEKDVKYKDVVICEVGSVMGTYTSKGAIL
                     ITAI"
     gene            9021..9593
                     /locus_tag="OE968_002408"
     CDS             9021..9593
                     /locus_tag="OE968_002408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCP7219684.1"
                     /translation="MKTNNMKQAILSSATNLIAKNGVQNTSLADIAKDVNISKGTLYY
                     HYASKDDIIYDIADTHLEVITSAILNCVKNVKSKNSQIEMVNLILEKISTIESRGRVH
                     MYLICEAITSNNDLKERIRLKYIEWRTTLKSEIVESLEKYNSSENEQDAESFSFLLMS
                     IVDGLVVQSLLKTEKIPYENIASFLVNHWI"
     gene            complement(9756..10028)
                     /locus_tag="OE968_002409"
     CDS             complement(9756..10028)
                     /locus_tag="OE968_002409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219685.1"
                     /translation="MLRERFVVRNHHNPHTSGCCGTGGEGCCGGDNHEHSHQHSHSHG
                     HEHEHVNGVGHDHNHDDGFSGTHEHSHEHTHTHGHEHSDGHTHEHK"
     gene            complement(10155..11027)
                     /locus_tag="OE968_002410"
     CDS             complement(10155..11027)
                     /locus_tag="OE968_002410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HCP7219686.1"
                     /translation="MYGESKKLSIDNNIFLQYCLIILGMILSTLGINLYLAPAKLLSG
                     GVAGICVILYKLFGINQGISSFLMNIPIFIIARKYFDNKFLLISFVNMLLFSLALGLT
                     QDIAKYFPIDDTMLQCIYGGALTGIGMGLTFKARATAGGLDIIAAIMKRKYDIPMKNT
                     FLFINFFVVCAGAFLFGAKLVMYTLITMYIISFTMDIGKDCFDRKKSILLISNKYDEI
                     SKVIMNKMGRGVTFLEAEGAYTQNKKKMIYCIISANEIGKFKDLIYDMDSEAFISVNN
                     VEEVKGGGFKDKFL"
     gene            complement(11314..14421)
                     /locus_tag="OE968_002411"
     CDS             complement(11314..14421)
                     /locus_tag="OE968_002411"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HCP7219687.1"
                     /translation="MAKFKPLVDSSVKQAEAQVFDYWKDINILEKTLEKGKDDPSFVF
                     YEGPPTANGNPGVHHVLSRTLKDSVCRYKTMSGYQVKRKAGWDTHGLPVEIQVEKELG
                     LTSKQQIEEYGIAEFNQKCRESVFSFEKQWRIMTERMAYEVDLDNPYITLDNNYIESV
                     WWILNKFNKEGYIYEGHKILPYCPRCGTGLASHEVAQGYKEVKTNTVIAKFKKKDADE
                     YFLAWTTTPWTLPSNVSLTVNADVDYLKVKKGDEVYYVSKPLADKVLGEDYEVLEEMK
                     GKDLEGLEYEQLMPFVEVDKKAFFITVGDYVTTEDGTGIVHTAPAFGEDDYNTGKRYD
                     LPVIQPVDETGKFTSTPWEGRFVMEDGLDVEIIKWLASENKLYSKEKVVHNYPHCWRC
                     QTPLVYYAKPSWYIEMTKLKDKLIENNNGVKWFPSFVGEKRFGNWLENLNDWAISRTR
                     YWGTPLPIWRCECGHTDSVGSRAELAEKAIEDVNPETVELHRPYVDDIHLKCEKCGKP
                     MTRVTEVIDCWFDSGAMPFAQHHYPFENKENFDQLFPADYISEGIDQTRGWFYSLLAV
                     STFVLGKAPYKSVLVPDLVLDKDGKKMSKSRGNTVNPMELFDQYGADALRWYLLYVSP
                     PWTPTKFDMDGLKEIQSKFIGTMKNVYNFFTLYANTDDINPTEFFVEYKDRPELDRWI
                     LSKFNNLMKDVEENLAIFELNKTLRMIQDFINDDLSNWYIRRSRRRFWATELTEDKKA
                     VYNTTYELLHGLCRAIAPFAPYMSEEMYRNLTGEVSVHLAEYPKCNEELVDTKLEEKM
                     DLAKNLVTLGRASREVERIKVRQPLQKVLVDGKFEDTISDVVDLIKEELNVKEVIFAK
                     DLDEYMNFSLKPNFKEAGPLLGSKMNLFVGALSKLNAHETANKLEKGETLTVDLDGEA
                     FEFNKDLVLIGITAKEGFNVSVENNLFVILDTKLTEELINEGYAREFISKVQQLRKSN
                     NFEVLDNIVIEYCGDDEIAKAVDHFNEYIKSETLALEINRVDDKSLEEQNLNDHMTGI
                     KVIKK"
     misc_binding    complement(14514..14746)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(14921..15448)
                     /locus_tag="OE968_002412"
     CDS             complement(14921..15448)
                     /locus_tag="OE968_002412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HCP7219688.1"
                     /translation="MLTPIEIENKEFKKGLRGYRDEEVDEFLDIIKEDYESLCRENTA
                     LKEKLGLYQDQVNKYENIEETLKATLITAQSAAEDTCSAANKKAKIIVEEADLKARQI
                     IEQANNRVIEIRKEYDALVKEFKIFRNKFKSLLEDEIRSVDEIFYDVDEKCVNAFEGT
                     TVYNYSNDEAATTLE"
     gene            complement(15483..16268)
                     /locus_tag="OE968_002413"
     CDS             complement(15483..16268)
                     /locus_tag="OE968_002413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HCP7219689.1"
                     /translation="MDKLKLTNHIKDIDLKNKMFKVIDKANSCIKNYDVKSTEFLNPY
                     EVKNAVAILNSTNEIKYSVDGGYEQAERSTVFIYPFYMEYEDIEDTLRFLQIEGNFKF
                     KNISHKDYLGSILGLGIKREKIGDIIIHDSFCQVVVSSDICDFIIVNLEKVSRNNVIV
                     KEISRENIVNSSSKYKEVSFTVSSDRLDCVISGIYNISRQDSAKYINGEKVHVNYEKI
                     TSTSKIVKNDDLISIRGKGRAKVTQIGDITKKGKIKVQARLIV"
     gene            complement(16278..16535)
                     /locus_tag="OE968_002414"
     CDS             complement(16278..16535)
                     /locus_tag="OE968_002414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HCP7219690.1"
                     /translation="MGTIRIALYYLLDIIAWMIVIKSLMTWFPNGRQSKIFDILENLT
                     EPIEGPIRSIMYKYTNGPIDFSPLIAIVLLMFLRQLVLVIF"
     gene            complement(16554..17012)
                     /locus_tag="OE968_002415"
     CDS             complement(16554..17012)
                     /locus_tag="OE968_002415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HCP7219691.1"
                     /translation="MSNGIISKFKNWIVDEEEDYIEDEYESGMDDIVQEEEMNSGFST
                     AKANKIVNLHTTSQMKVVIVEPKVYDEAATIADHLKQRRAVIVNLEGLTNSEVRKSIF
                     NFMNGAVYVLDGSIQKVSKSIFILAPNNVDIDANMKKELESKAFFPWQNK"
     gene            complement(17052..17756)
                     /locus_tag="OE968_002416"
     CDS             complement(17052..17756)
                     /locus_tag="OE968_002416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HCP7219692.1"
                     /translation="MGSIKDNLSEIRNKIDKAAKKVDRDSKEITLLAVTKTVDVDLVN
                     EAMREGITSVGENKPQELARKYDIIGDKLNWHLIGTLQTNKVKYIIDKVCMIHSLDRI
                     ALCEEIQKRAEQINREIDCLVQVNISKEESKHGLDREEVVDFVKEVSEKYKNIKIKGL
                     MTMAPFIEDEDEIRGVFKGLKDLSKQIKELNIPNVGMDVLSMGMSHDYEIAIEEGATI
                     VRVGTSIFGERNYNKK"
     gene            complement(17766..18401)
                     /locus_tag="OE968_002417"
     CDS             complement(17766..18401)
                     /locus_tag="OE968_002417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219693.1"
                     /translation="MKKVKYTRLVILGILIYLVFNILVMIISKNVDTLVLKNEKVDAK
                     IHVKGTIEKDANDQSNYLSTYISKEDSNNFEKNQNVIIEYHEQKLDAKVYKIYENNNK
                     IMVKLKISNQIVANQDTSVEEFDIIYNQMECLKIPKTSIKTKDNKRGVYVIDEQSQSV
                     KFVILEGITYENESSVFVDYYKNDINGVTSVNLYDKIILRPNSINTNIRIK"
     gene            18782..19822
                     /locus_tag="OE968_002418"
     CDS             18782..19822
                     /locus_tag="OE968_002418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCP7219694.1"
                     /translation="MSEILLGTGLLLLVLCCFTIFSYKAPYGMKAMGALANAACATFL
                     VEAFNLSLLGDVLGMEFFRSVGAANGSLGGVAAAILVPLALGVSPVYAVLIGLSCLDF
                     SILSGFVAGYFVSFLIKFIEKKVPPGVDLVVVILLCAPLSRLIASNVDPLVNSTLLQI
                     GQVLIEATNISPIIMGIILGGLITVVGTSPLSSMALTSIIGLTGLPMAIGALGAFGSA
                     FMNSTLFAKLKLGSKKDIISVAIEPLTQSDIISANPIPIYSTNFFGGAFSGIIVALMG
                     LVNMTPGTATPVAGFAIMFAYNPVQQVLITAGLCALFNVIAGFLGSKIFSTFKVLTAG
                     EIRGTDVEEEIA"
     gene            complement(20285..21640)
                     /locus_tag="OE968_002419"
     CDS             complement(20285..21640)
                     /locus_tag="OE968_002419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009170073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HCP7219695.1"
                     /translation="MNVGNILETIKMIDEEQLDIRTITMGISLLDCIDPDGDKAREKI
                     YNKIMSSAKDLVKVGKDIEREFGIPIVNKRVSVTPISIIAGATDENDYVKFAQTLDKA
                     AEDLGIDFIGGFSALVQKGYTKGDKILIKSIPKALASTNKVCASVNVGSTRCGINMDA
                     VKEMGEIIKETAELTKDAKGFGCAKLVVFCNAVEDNPFMAGAFHGVGEADRIINVGVS
                     GPGVVKRALEKVKGEPFDVVSETVKKTAFKITRVGQLVAKEASSRLDVPFGIIDLSLA
                     PTPAIGDSVANILEEMGLEVVGTHGTTAALALLNDAVKKGGVMACSHVGGLSGAFIPV
                     SEDAGMIDAVIKGALSIDKLEAMTAICSVGLDMIAVPGNTTAGTLGAMIADEAAIGMI
                     NNKTTAVRIIPAPGCDVGDMVEFGGLLGRAPVMPINTNSSELFTQRGGRIPAPIHSFK
                     N"
     gene            complement(21666..21935)
                     /locus_tag="OE968_002420"
     CDS             complement(21666..21935)
                     /locus_tag="OE968_002420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010963800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HCP7219696.1"
                     /translation="MKAILTVIGKDKPGIVAGISDELYKQNINIVDISQKILQDYFTM
                     IMIVDLEKSLNSFEKTVEDLVERGKKLSVDVKIQREEIFNSMHNL"
BASE COUNT         7365 a         3698 c         2570 g         8396 t
ORIGIN      
        1 ttagattata taatctaaat aaattaaaat tcaaaagtta actaaactaa tatttgtagg
       61 gagaataaat gaaaaaattt aggaaacata aaagtattag taattgtata tctatattgt
      121 tgatattata tctaacttta ggtagtttgt tacctaataa catttatgca caagatttac
      181 aaagctatag tggaaaagtt tgtaatacta cttacaaggc tcctatagaa agatcagaag
      241 gattttttta aagataaaga aaaggctaaa gaatgagaaa gaaaagatca aaaacttgaa
      301 aaatctgaaa aagaagtatt aggatcatat aaaaaagatt ctatagagat aagcaaatat
      361 tctcagacaa gaaattattt ttatgattat caaatagaag caaattcttg agaaaaagaa
      421 tatagagaac ttcgaaatgc tatatcaaaa aataaaatag ataaacctat gtatgtatat
      481 tattttgaat ctccagaaaa atttgcattt aataaagtaa taagaacaaa aaatcaaaac
      541 gaaatttcat tagaaaaatt taatgagttt aaagaaacta tacaagacaa attattacca
      601 tacaacagat aattcaactg ctgttcaaaa tagcaatgga taatcatgaa atactggatt
      661 aagtataaac aaaggagaat ctgcatatat aaatgcaaat attagatact acaacacagg
      721 tactgcacct atgtacaaag tgacaccaac aacaaattta gtgttagatg gagatgcatt
      781 atcaactatc aaagcacaag aaaatcaaat tggcaataat ctatctcctg gaaatactta
      841 tctcaaaaaa ggattttcac ctatggctct taacacaatg tatcaattta gttctagact
      901 gattcctata aattataatt aattaaaaaa attagatgat ggaaagcaaa ttaaattaga
      961 aacaacacaa gtaagtggaa attttggtac aaaaaatggt tctggacaaa tagtaacaga
     1021 atgaaatagt tggtaagacg atataggtca aattgacagt atttctgtat ctattatatt
     1081 agatacagaa aatgaatctt acaaaagaag aattactgct aaaagtttac aggtcccaga
     1141 agataaaaca cctgaactta caattggaga agcaattgaa aaaacttttg gcactactaa
     1201 aaaagatggt ttgttatatt ttaataatat accaatagat gaaagttgtg ttgaactcat
     1261 atttgatgat aatataggca ataagattaa agacagttta aaaactttgt ctgataaaca
     1321 aatatgtaat gttaaacttg aaagaggaat gaatatactt ataaaaacac caacttactt
     1381 tactaatttt gatgattaca ataattaccc tagtatatgg agtaatgtta atactacaaa
     1441 tcaagatggt ttaaaaggct cagcaaatag attaaatggt gagacgaaga ttaaaatacc
     1501 tatgtctgaa ctaaaacctt ataaacgtta tgtttttagt aaaattcaaa aaatccttta
     1561 acatataatt caataattgt aaatataaaa gtaaaagaag aaaaaacgga ttatttggta
     1621 ctagaacaag gatatacaaa atttagttat gaatttgaaa ctactgaaaa agattcttct
     1681 aatataaata tagcattaat tgatagtgat acaatatact tagataactt atctattaca
     1741 gagctaaata gtactcctga aatacttgat gaaccagaag ttaaaattcc aactgttcaa
     1801 gaaataatag ttacacataa aatatattct gcagatttta aatttaatcc aagtacaata
     1861 aaggcttata taaatggtat gtattttaca ccaacataaa ctaataaaga agctctcgat
     1921 tatgtccaaa aatatagagt tgaagctact ttacaatatt ttggatttaa agatattgaa
     1981 actaaagata aagaattgcg taattattta ggagatacaa atcaacctaa aactgattgt
     2041 gttaatctta ggagttattt tacaggtgga gaaaatatta tgacatacaa gaaattaaga
     2101 atatatacaa ttactcaaga tgatagagag ttattggttc ttagtgttga ttagtatcaa
     2161 atgatttaaa tttatcccca caatacaata tgtatttacc ttataaagta ttaaaaaatt
     2221 aactttataa ggtatttttt atttaaatat tatcttcttc taatatattc ttttttagaa
     2281 ctatattgta ttaaaaagat aattatctgt atcatatcac ctatatataa acataaattc
     2341 atttaattat ataaatttaa aaaatatttt tttgatatat tattgacaat tttcattata
     2401 agagttaaaa ttaactcata aattacatat tgggtataaa atacaatgta tgttagaagt
     2461 tgtttcagaa ggctatggtt ttctgatttt tttatgctca gtagtgatat gcaaaaaaga
     2521 caaagttgac atcagttaac ttttaccttt attctacttt ccccaaagta agaataatct
     2581 aacccctttg agatgagcaa aagctcatct ttttttatta tcaaaagatg ctgtctcaaa
     2641 atagagataa tcctcttttt cattgttgaa atgattaaaa tatattttat ttcatacaaa
     2701 aaagagtgcc tcatgaacaa aagttcactt tgagactctc tctttcatat catatacctt
     2761 tttaataact ttaaaattta tttatcaagt aaagatagct aataattagt atcttctctc
     2821 tataaatcca acttttttat aaacttttct aagagttttt ctagcttgtt tttcggcttt
     2881 ttctgctccc atactatata ttttttctaa ataatcttta ttattaagaa ggtcaacata
     2941 tttttctctt ataggtctta aagcttctga tactacttca gccacatctt ctttaaatat
     3001 gccataaccc tttccttcat acatgtttac aatctcttct acactctttt tacttaaatt
     3061 agaatatata tcaattaggt ttttaatacc tggttgttca tcattgtatt ttacaacacc
     3121 taaagaatca gtaacacttc tttttatctt tctctttata gaatctgaat catctgctaa
     3181 tagtataaat gcattttcat ttgaatcgga tttactcatt tttttagttg gctcttgcaa
     3241 actcatcact cttgctccac cttttgggta gtatccttct ggaactacaa aagtaggtga
     3301 aaatctatta ttaaacctat ttgctaaatc acgagctaat tctaaatgtt gtttttggtc
     3361 atctccaact ggaactaggt cagtttgata caacaatatg tcagcagcca taagaactgg
     3421 atatgtgaat aaacctgcat ttagatttgc ttcactcttt tgtgatttat ctttgaattg
     3481 agtcattcta cttaattcac ccatataagt catagtattc aatacccaca taagttcaac
     3541 atgctctttg acatgtgatt gtataaatat agtatttttt tctgggtcta atccacaagc
     3601 tatatattga gcaagtaatt ctatagtatt ggctcttaaa actttagggt cttgaggtac
     3661 tgttattgca tgcaaatcaa ctatactata ataacaatca taattgtctt gaagttcagt
     3721 ccagtttttt atagctccta aataatttcc taaagtcatt ttgcctgatg gctgtgcacc
     3781 acttaatata actttttttt cactcatttt tttgtacctc cttatatatt tatattgatt
     3841 ttaacatatt taaaactatg tctttagagt tattggcagc atcatgtaca aatacatcat
     3901 aagtaacatc agcacttcca tctgccttat cagacattgc tcttattatt acaaatggag
     3961 tattatttaa atagcataca tgagctatag ctccaccttc catttctcca caatatccac
     4021 caaaatcatt tactaattct tcttttaatt ctttagaatt tataaattta tctcctgtaa
     4081 ctactcttcc ttttaatact ttatgagtct ttacttcttc cacagaagat ttgtaagcag
     4141 catctataag tctttcatct gctttaaata cagaagtctt cattcttggt ataactccct
     4201 tagggtctcc aaatgctgta gtgtctacat catactgtat agcatcagtt gatattacta
     4261 tatcattaac atcaagtttt tcgtttaaag ctcctgcaac acctgtatta acaatagcat
     4321 caaccttaaa ttcgcttatt agtatctggg cacaaagagc agagttaacc ttacctatgc
     4381 cacactttac taacactaca ttcttacctt ccaaaattcc cttataaaat tctaagctag
     4441 ctttttttat agtctctcta atatccatta aatcaactaa aatactaact tcttcatcca
     4501 ttgcacctat aattcctatt acgttcattt ttcctcctaa attttctata ttaaaaaatc
     4561 cgtcctaaat caataggacg gatatatttt ccgtggtacc acctaaattt atatacactc
     4621 aaaattgaat atatatatct taatatatgc tataacgtgc atacacgata tcaaatactc
     4681 tgtaatctta aattacattt cattttactc ctcaaagacc cattcaataa atacttttta
     4741 ttaagttctc agcatcctta attctctgtg caaaaatata tttatttact atttcttatc
     4801 tcaggattta atttattaat ttctttattt tataatattc cttacactat aaattgtcaa
     4861 ctatatatta taatatccaa aagaaatttt taaaatacat tttatttagc tgttttcttt
     4921 tcatatctat tccataacca tagaccagat aatataacta gaagacctcc accaatcatc
     4981 tctatctcat atataacatt ttcagcaaat gtaggcataa ctggtgctgc agataataat
     5041 atacccacta cagttacaac taaaaccatt tttgctaaac ctaggcaagt acttgttgat
     5101 tttgccatag tataaggtct aatttcatct ggtctctctt ttcttagttt aatataagaa
     5161 gcatataaca atacatatgg gaataatgca gttaatgctg tcatagttac aagaacattg
     5221 tatatagcat caacagaagg cattaatgta gtcaccaata gtattatagt aactattatt
     5281 gcttgaagta taactgcttt agaaggtatc ttgtgttcat ttacctctac taaactatct
     5341 ggaaatattc cttttttaac actaccaaat aacattttta ttggtgatgc tatgtaaaga
     5401 actattgctc ctaatactga aaaagctata ccaaaagcta ttaattgaac caaccaagaa
     5461 ccaattccta aagacgcaca aacagcagaa agtgcatcta atacaccttt agaagcagta
     5521 atttggtctg gtggtattat cattgttatt gcaattgaac ctaatacata taatgaagct
     5581 actattccag ctgatattaa tattgcctta gggaagttct tttcaggctt atctatttct
     5641 gttatgaagt tagcagcagt ctctgctcct gctaaaccaa acattatagc tgatatagca
     5701 acaaatgcat ccatattaag ttttggagtc attgaagcta ttgtgtatgt agaagctata
     5761 tcatgttttt tcaatacaaa tactgctaca aatgaaaata ttataagtat agcacttggt
     5821 attgttgaac ctaatgcacc tgtattagta aatatttttg taaaacttat tcctttagtt
     5881 gctataagag ataatgccca gaatattatt aaagataata taagtacaaa catcttatta
     5941 tcagcaaggg ctggatttcc tattgtataa gaaacattta ctgctaagaa agttaaaaat
     6001 gaagaatacc aaaatatttt agctgtccag tttaaccaag aaactaaaaa tccatacttt
     6061 tctccaaagg cttccttaac ccaatcgtaa agacctccat cacctttttg atatgtagaa
     6121 gctaattcag cacaaattaa agctcctggt acaaagtata taaatgagaa taataaccac
     6181 ataggtattg cacctaatcc taaaccaaag cttgatgctg tagatttagc tatccatctt
     6241 ataccatata aagctgatac attcataaat accaaactcc ataggcctat ttttttcttt
     6301 tccatcctaa tttaatttcc cctctctatt aattatttta aatttaattt caaaattaat
     6361 aaaatagatt cattattatt aaactgatat ttttcaaaat atttgcatat tcaaaaacag
     6421 ttttaataat aaaccttaaa tactttgaaa tcaaatctta ttaaaaatga taaatttaaa
     6481 agttttacca ctttaattct aatgatacta aatttttaaa attgtttcaa tattatttta
     6541 ttataaaatt ttatttatta tttttcatta gtatataaaa agataaaata cataacttta
     6601 tagacttaat ttattacttt tatagaattt tcacaataaa aagtcatttt acttccgtat
     6661 ttaatgcaaa agtagagatt aaacttaata taaaaaatat ataacaaatt ttttttatat
     6721 ttctagaaga aaagtatact cttttttgtt taataatgct aaaattgatt tgtattgaat
     6781 tttgattagg aggaaattat tatgaaagct caaagattaa atgctgtact tgaacaaatg
     6841 aaaaaagatg atatttctca aatgttagta agtgacccta cttctatatt ttatcttaca
     6901 ggagtactaa tccatccagg cgaaagacta ttagcattat acttaaattt aaatggcaat
     6961 aataaattat ttataaatga attattccca gtttcagaag atttaggtgt tgaaatggtt
     7021 tggttcaatg atactcaaaa tccagtagaa ataataactg aacatataga caaaaatgct
     7081 actatgggtg ttgataaaaa ctggccagct agattcttat taaacttaat agaattaggt
     7141 ggaggaagta agtttgtaaa ttcatcttat ataatagata ctttaagaat gtgtaaagat
     7201 gaagaagaaa aagagttaat gagaatagct tcaaaattaa atgacaaggc tatggaacaa
     7261 cttaaagcta ctgtttctgg tgaacttaca gaaaaacaac ttgttggtaa attatctaaa
     7321 atatatgaag acctaggtac tgatggattt tcatttgacc ctattatagg ttttggacct
     7381 aatggagcta atccacatgg tgaacctgga aatgcacttg tgaaaccagg agatgcaata
     7441 atcttagata taggttgtat aaaagataac tattgtgctg atatgacaag aactgtattc
     7501 tataaagaaa tacctgaaaa aggtagagaa atatttgaaa tagttcttga agctaataag
     7561 agagctgaag ctattgtaaa accaggtgtt agattctgtg atatagatgc tgctgctcgt
     7621 gactacataa ctgaaaaggg atatggacag tacttcactc atagaactgg tcactctata
     7681 ggacttgaag ttcatgataa aggagatgta tcttctataa atacagatac tgtacaacca
     7741 ggaatgatat tctctataga gccaggtata tatttaccag gtgagttcgg agttagaata
     7801 gaagatttag tacttgttac tgaagatggt tgtgagatat taaacaaaca tgacaaagaa
     7861 atatgtgtag ttggttaatt ctaaaatcaa tttgataaaa ttaaaaagcc atataaaaat
     7921 gttttaaaca tttttatatg gctttaattt ctcaatctat gatttatttc aatccattat
     7981 ttatattgca gtatttatat tgcagttatt aagattgcac cctttgaagt atatgtcccc
     8041 atcactgaac caacttcaca gattacaaca tctttgtatt ttacatcctt ttccataact
     8101 tcccttacct tttgagcctt ttctgggcaa ttagcatgtc ctataaataa aaccttttct
     8161 tctttatctt taatttttga ctctactaaa gtaatcagct ttttcaaact gtttccttca
     8221 cctcttgcct tatctatagg agttacaacg ccatctgcaa cttgtattat cgccttaaaa
     8281 tttaaggtat ttataatttt tcctgctatt ggatttattc taccaccctt aatagcattt
     8341 tctaaagttt caagtgttcc aaaaaatgga ggattatctt tatatttatt tattattgaa
     8401 acaatctctt caatttcttt tccttctttt attaatattg ctgcttttaa cactaattgt
     8461 cctattccaa ttgacccact aagtgaatct ataacctcaa ctttcttgtt atttccttcc
     8521 ttttcaaaca tatcttttgc taaaagtgca ctattataag tcccagataa tcctgaactt
     8581 atattaatca ctaatacact ttcttcctga caatggtatg cttctaaaaa tttatcagga
     8641 gaaggacatg atgtttttgg tagtacttta ctctcactca tttttctata gaaagtttca
     8701 ttatctattt cctttccaga tatataactt tcttctccaa aagatacatt taaaccaaca
     8761 acttctatgt tgtatttttc tattatatca tcaggtaagt cacatgcact gtccactatc
     8821 aattttattt tatccatatt aacctcacta taagatatta ttttatttat tcagtcggtc
     8881 gtacgaccga tttaattatt attttatata ttgaatgaaa aaaagtcaat agatatagat
     8941 tctcgcttta ttgacaataa atatccataa gcttataatg ttattaattt gttataaata
     9001 tacatggaaa ggtaggtttt atgaaaacaa ataatatgaa acaggctatt ttatcatctg
     9061 caaccaattt aatagccaaa aatggagttc aaaatactag ccttgctgat attgcaaaag
     9121 atgtaaatat aagtaaaggt actttgtatt atcactacgc atctaaagat gatattatat
     9181 atgatattgc ggatactcat ttagaagtta taactagtgc tatactaaac tgtgtaaaaa
     9241 atgtcaaatc aaaaaattct caaatagaaa tggttaactt aatcttagag aaaatatcta
     9301 ctatagaaag tcgtggtagg gtacatatgt atcttatttg tgaggcaatt acttcaaata
     9361 atgatttaaa ggaaagaata agattaaaat atattgaatg gagaactact cttaaatctg
     9421 aaattgttga atcactagaa aaatataata gtagcgaaaa tgaacaggat gctgaatcat
     9481 tttctttttt actcatgtca atagttgatg gtttagttgt ccaaagttta ttaaaaacag
     9541 aaaaaatacc ttatgaaaat atagcttctt ttttagttaa tcattggatt taaacttaat
     9601 acttagataa ttaataaaag tgaactattt aagttatcta ctttaacagt tcactttctt
     9661 atttattctc aataattttt acttaaaaca ttcaattttt atttaaacct tcatggaatc
     9721 acaaaataaa aatctcttat aaatttaaaa tgtttttatt tatgttcatg tgtatgccca
     9781 tctgaatgtt catgaccatg tgtatgtgta tgctcatggc tatgctcatg agtacctgaa
     9841 aaaccatcat catgattatg gtcgtgacct acaccattta catgctcatg ttcatgccca
     9901 tgactgtgag aatgttgatg tgaatgttca tggttatctc ctccacagca tccttctcct
     9961 ccagtcccac aacacccact tgtatgtgga ttatgatgat ttcttactac aaatctctct
    10021 cttaacataa ttcttatacc tcctagtata ttattgagta cttcatgtac cccattaact
    10081 atggtataca tctaactagg tataatctca atacatatgt cattttttaa catatataat
    10141 taacatatat aatcttaaag aaatttatcc ttaaaacctc caccttttac ttcttcaacg
    10201 ttattgacag aaataaaagc ttcactatcc atatcataaa ttaaatcttt aaatttacct
    10261 atttcatttg cagatattat gcaataaatc atctttttct tattttgtgt atatgcacct
    10321 tctgcctcca aaaaagtgac tcctctaccc attttattca ttatcacttt ggatatttca
    10381 tcatatttat ttgatattaa aagtatagat ttttttctat caaagcaatc ttttcctata
    10441 tccatagtaa aagaaattat atacattgta attaaagtgt acatcaccaa tttagctcca
    10501 aataaaaaag ctcctgcaca tactacaaaa aaattaataa ataaaaatgt atttttcata
    10561 ggtatatcat actttctttt cattatggct gctattatat caagtcctcc agcagtagct
    10621 cttgctttaa aagttaaccc catacctata ccagttaatg caccaccata aatacactgt
    10681 agcatagtat catctattgg gaaatattta gcaatatctt gtgttagccc cagtgctaga
    10741 gaaaatagta acatattgac aaaacttatt agcaaaaatt tattatcaaa atactttcta
    10801 gctataataa atattggtat gttcatcaag aaacttgata ttccctgatt tataccaaat
    10861 aatttgtata atataacaca aattccagct actcctccac ttaataactt ggctggtgct
    10921 agatataaat ttattcctaa ggttgataga atcataccca atataatcag acaatattgt
    10981 aaaaatatat tattatcaat acttagcttt ttactttcac catacatcaa aacgcacccc
    11041 tttgcataat aaataaacca ccctgcataa cacacgataa atttacaaat aaatttatca
    11101 gaagtagttt cctaaaaata ttattcatcc tcacttaaac gtttattcat taatattcta
    11161 tcacatgaca taaataattt atatgattta tacagattta tttattgtaa attttggaat
    11221 attaaaacat tttattgaat agataattat attacataaa aaatccctat agaaatctat
    11281 aaactaattt ctatagggat tttgattaac taactatttt tttataactt ttatacctgt
    11341 catatggtca tttaagtttt gttcctctaa agatttatca tctactctgt ttatttctaa
    11401 agctaaagtt tcagacttga tatattcatt aaaatggtca acagctttag caatttcatc
    11461 atcaccacag tattctatta ctatattatc taatacttca aagttattag attttcttaa
    11521 ttgctgtact ttagatataa attctctagc ataaccttca ttaatcaact cttcagttag
    11581 cttagtatct agtataacaa aaagattgtt ttcaacagat acattaaatc cttccttagc
    11641 agttatacct attaatacta aatccttatt aaattcaaaa gcttcaccat ctaaatcaac
    11701 tgttaaagtc tcaccttttt caagtttatt agcagtttca tgagcattta atttacttaa
    11761 tgctccaacg aataaattca tcttagaacc taataatggc cctgcttcct taaagtttgg
    11821 ttttaaacta aaattcatat actcatctaa atctttagca aatattacct ctttaacatt
    11881 aagctcttct tttattaaat caactacatc acttattgta tcttcaaact taccatctac
    11941 taacactttt tgtaatggtt gacgaacttt tattctttct acttctcttg aagctctacc
    12001 taaagtaact aagtttttag ctaaatccat tttttcttct aatttagtat ctactaactc
    12061 ttcattacat ttaggatatt cagctaaatg aacagatact tctcctgtta agtttctata
    12121 catttcttct gacatatatg gtgcaaatgg agctatagct ctacaaagac catgtaacaa
    12181 ttcataagtt gtattgtaca ctgctttttt atcttctgtt aattcagttg cccaaaatct
    12241 tcttcttgaa cgtcttatat accagttaga taaatcatca tttataaaat cttgtatcat
    12301 tcttaaagtt ttatttaact caaatatagc taaattttct tctacatctt tcattaaatt
    12361 attgaactta gataatatcc atctatcaag ttctggtcta tctttatatt ctacaaaaaa
    12421 ttcagttgga tttatatcat ctgtgtttgc atataaagta aagaagttat atacattctt
    12481 catagtacct ataaatttac tttggatttc ttttaatcca tccatatcaa atttagttgg
    12541 agtccatggt ggagaaacat atagtaaata ccatcttaat gcatctgctc catattggtc
    12601 aaataattcc attggattta ctgtatttcc tcttgattta ctcattttct taccatcttt
    12661 atcaagtaca aggtctggaa ctaaaacact cttatatggt gcttttccta atacaaatgt
    12721 tgatactgca agtaatgagt agaaccaacc tctagtctgg tctatacctt ctgatatata
    12781 gtcagctggg aacaattggt caaagttttc cttattttca aatggatagt ggtgttgagc
    12841 aaatggcata gccccactat caaaccaaca gtctataacc tctgttactc ttgtcattgg
    12901 ttttccacat ttttcacatt ttaagtgtat atcatctaca tatggtctat gaagttcaac
    12961 tgtttctgga tttacatctt ctatagcttt ttcagctaat tcagctcttg aaccaactga
    13021 atctgtatga ccacattcac atctccatat aggaagtgga gttccccaat atctagttct
    13081 tgatattgcc cagtcattta gattttctaa ccagtttcca aatctcttct ctcctacaaa
    13141 acttgggaac cattttacac cattattatt ttctattaat ttatctttaa gtttagtcat
    13201 ctctatatac cagcttggtt ttgcatagta tactaatgga gtttgacatc tccagcagtg
    13261 tggataatta tgaactactt tttctttgct atataattta ttttcagaag ctagccattt
    13321 tattatttca acatctagcc catcttccat tacaaatcta ccttcccaag gagtagatgt
    13381 aaatttacca gtttcatcta ctggttgaat aactggtaaa tcatatcttt tacctgtgtt
    13441 gtagtcatct tcaccaaatg ctggtgctgt atgaactata ccagttccat cttcagtagt
    13501 tacataatct cctactgtaa taaaaaatgc ttttttgtca acttctacaa aaggcattaa
    13561 ttgttcatat tctaaacctt ctaggtcttt acctttcatt tcttctaaaa cttcataatc
    13621 ttcacctagt actttatcag ctaaaggttt agatacataa tatacctcat cacctttttt
    13681 aacttttaaa taatctacat cagcatttac tgttaatgaa acatttgatg gtaaagtcca
    13741 tggagttgtt gtccatgcta agaagtattc atcagcatct tttttcttaa atttagctat
    13801 aactgtatta gtttttactt ctttatatcc ttgtgcaacc tcatgactag caagaccagt
    13861 tccacatctt gggcaataag gaagtatttt atgcccttca tatatatatc cttctttgtt
    13921 gaatttgttt agtatccacc atacagactc tatatagtta ttatctaaag ttatatatgg
    13981 attatctaaa tcaacttcat aagccattct ctcagtcatt attctccatt gtttttcaaa
    14041 tgagaaaact gactctctac atttttggtt aaattcagct attccatatt cttctatttg
    14101 ttgcttacta gtaagtccta actctttctc tacttgtatt tcaactggta atccatgtgt
    14161 atcccaacca gcttttctct ttacttgata accagacatt gttttatatc tacaaactga
    14221 atctttaagc gttctagata aaacatggtg tactccagga tttccattag ctgttggagg
    14281 tccttcatag aatacgaaac ttgggtcatc tttccctttt tctaaagttt tttcaagtat
    14341 atttatgtct ttccaataat caaaaacttg tgcttctgct tgttttacag aactgtctac
    14401 caatggctta aatttcgcca tgtaaatcac cctttcctac taaatattat aattccaaaa
    14461 ttttttattc tttcacataa atttaaatac taaaaaactc gcccccttta aaccaaaggg
    14521 acgagttata aatcgcgtta ccaccctaat tctatatgta aactaaatac tagctacata
    14581 taacactcta atagtataac ggtactaacc ggcacagctt agtagaattt aatcgttcag
    14641 cctgcagctc aagagtgatt tttatcttta taaattcatt ggttctcagc atacccaatt
    14701 ctctgtaaaa ttatctaaag ataaatgtct ctatcaacgc ttttaaaaat ttatctgtgt
    14761 ttatatgaaa ttctataaca aataatttga atagtcaata tatttttgaa aaatataata
    14821 atttctattt ttcttacatt tttatcctat ttttaatctt tgttatagat ttctcaaact
    14881 cacacaatta ttctacataa aaaataaaca aattacaagc ttattctaaa gttgtagcag
    14941 cttcatcatt actataatta tacactgttg ttccttcaaa tgcgtttaca catttttcat
    15001 ctacatcata aaaaatctca tcaacacttc ttatttcatc ttctaacagt gatttaaatt
    15061 tatttctaaa tatcttaaat tctttgacta aagcatcata ctcttttctt atctctataa
    15121 cacggttatt agcttgttct ataatttgtc tagcttttaa atcagcttct tcaacaatta
    15181 tcttagcctt tttattagcc gcgctacaag tgtcttctgc tgcactttga gcagttatta
    15241 aagtagcttt tagtgtttct tcaatatttt catacttgtt tacttggtct tgatataacc
    15301 ctaatttttc tttaagagct gtattttccc tacatagaga ttcataatct tccttgatga
    15361 tatctaaaaa ttcatcaacc tcttcatctc tataccctct taaacctttt ttaaactctt
    15421 tattttctat ctcaattgga gttagcatta catttcctcc cagctataat ttaaattagt
    15481 ccttatacaa ttaatcttgc ttgaactttt atttttcctt ttttagtaat atctcctatt
    15541 tgtgttacct tagctcttcc tttgcctcta atagaaatca aatcatcatt ttttactatt
    15601 ttagaagttg aagttatctt ttcataattg acatggactt tttctccatt tatgtatttt
    15661 gcactatctt gtctagatat attgtaaata ccacttatca cacaatctaa cctatctgaa
    15721 gatactgtaa atgatacttc tttatatttt gaagaactat taacaatatt ttctctggaa
    15781 atttccttta caattacatt atttcttgaa accttttcta agtttacaat tataaaatcg
    15841 caaatatcac tacttacaac tacttgacaa aagctatcat gtataattat atctccaatt
    15901 ttttctcttt ttatacctag acccagtatt gaccctaagt aatctttatg agatatattt
    15961 ttaaatttga aattcccttc tatttgtaaa aatctaagag tatcttctat atcttcatat
    16021 tccatgtaaa atggataaat aaatacagtg cttctttcag cttgttcata acctccatcc
    16081 acactgtatt ttatttcatt tgtagaattt aatattgcta cagcattttt cacttcatat
    16141 ggattaagaa actccgtaga cttaacatca tagtttttta tacaactatt agccttgtct
    16201 atcactttaa acattttatt tttcaagtct atatccttta tgtgatttgt tagttttaat
    16261 ttatccatcc tatcacctta gaatataacc aatactaatt gtcttaggaa catcaataat
    16321 actattgcaa ttaaaggaga aaaatctata ggtccatttg tatatttata cattatagac
    16381 cttattggcc cttctattgg ctctgtaaga ttttccaaaa tatcaaaaat tttactttgt
    16441 cttccatttg gaaaccaagt catcaagctt tttataacta tcatccatgc tattatatct
    16501 aaaagataat aaagtgcaat tcttattgtt cccatatatt aaccgccttt ttactattta
    16561 ttttgccaag ggaagaatgc tttactttct aattcttttt tcatatttgc atctatatcc
    16621 acattattag gagctagtat aaatattgat ttagaaacct tttgtatact tccatctaag
    16681 acataaactg ccccattcat aaagttaaat atagatttac gaacttcaga attagtcaat
    16741 ccttccaaat tcactataac tgcccttctt tgttttagat ggtctgctat agttgcagct
    16801 tcatcataaa ccttaggttc aactattaca actttcattt ggctagttgt atgtaaattt
    16861 acaattttat ttgcttttgc agtactaaag ccactgttca tttcttcttc ttgaactata
    16921 tcgtccatgc cactttcata ttcatcttca atgtaatctt cttcttcatc aactatccaa
    16981 ttcttaaatt tagatattat tccatttgac attattaact tcctccttaa aatttattca
    17041 aatttgagta attatttttt attgtagttt ctttctccaa agattgatgt tccaactcta
    17101 acaatggtag ccccttcctc tatagcaatt tcataatcgt gactcattcc cattgacaaa
    17161 acatccatcc ctacattagg gatgtttagt tcttttattt gttttgataa atctttaaga
    17221 cctttaaata cacctcttat ctcatcttca tcttctataa aaggtgccat tgtcattaga
    17281 ccctttattt ttatattttt atatttttct gacacttctt tgacaaagtc tacaacttct
    17341 tctctatcaa gtccatgctt agactcttct ttagatatat tcacttgtac taagcaatct
    17401 atttctctgt ttatttgttc tgcacgtttt tgaatttctt cgcataatgc aattctatct
    17461 aaagagtgta tcatacaaac tttatcgatt atgtacttaa ctttattggt ttgcaaagtt
    17521 cctatcaggt gccagtttaa tttatcacct ataatatcat actttctagc taattcttgg
    17581 ggtttatttt caccaacaga agtgattcct tccctcattg cctcattaac taagtctaca
    17641 tcaacagtct ttgtgactgc caaaagggta atctctttgc tgtctctatc tacttttttt
    17701 gcagctttat caattttgtt tcttatctca gacaaattgt ctttaataga acccattatt
    17761 atcacctact ttatccttat atttgtgttt atactgttag gtcttaaaat tattttgtca
    17821 tatagattaa cacttgtaac tccatttatg tcatttttat aataatccac aaatacagaa
    17881 gattcattct cataagttat tccttctaat atgacaaatt ttacactttg tgattgttca
    17941 tcaattacat atacaccacg tttattgtct tttgttttta tagaagtttt aggtattttt
    18001 aaacattcca tctgattata tattatatca aattcttcga cacttgtatc ctgatttgca
    18061 acaatttggt tacttatttt taattttacc attattttat tattattttc atatattttg
    18121 taaacttttg catctaattt ttgctcatga tattcaatta ttacattttg atttttttca
    18181 aagttattag aatcttcttt actgatgtat gtagatagat aattactctg gtcattggca
    18241 tctttttcta tagttccttt tacatgaatc tttgcatcaa ctttttcatt ttttaacacc
    18301 aacgtatcta catttttgct aattatcatt actaatatat taaatactaa atatataaga
    18361 ataccaagta tcactaatct ggtatatttt acctttttca aagactctcc ccctataaaa
    18421 ttactttcat tataagtact tcttctaaaa aatgtttatt ccttttttat aagctaatat
    18481 tttacgttct aataattatt ttttccatat taaatttatt ttttatcaat cttcctatac
    18541 aagactgcat tatttatata taattgtatt ataaagtata agtttaattt acattttata
    18601 cgttaagctt actttatatg tttttatagt tatttttatt tttagatgca atataaaacc
    18661 aattaagatt taaaataact tttgttatgt tgacatttat ttaggtaatc atttatgaat
    18721 taggataacg ttatcataac aaaagtttat gtcctaaaaa aaatacaagg aggattttct
    18781 tatgtcagaa attttattag gaacaggttt acttttattg gttctatgtt gtttcacaat
    18841 ttttagttac aaggccccat atggtatgaa ggctatggga gctctagcaa acgctgcatg
    18901 tgctactttc ttagtagagg cattcaacct ttctttactt ggtgatgttt taggtatgga
    18961 attttttaga agtgttggag ctgctaatgg tagtcttggt ggagttgctg ctgctatact
    19021 tgtgccttta gccttaggtg tatctccagt ttatgcagtt ttaataggat tatcttgttt
    19081 agatttttct atattatctg gattcgttgc tggatacttt gtttctttct taattaagtt
    19141 tatagagaaa aaagtgccac ctggagtgga tttagtggtt gtaattcttc tatgtgcacc
    19201 gctatctcgt cttatagcat caaatgtaga cccattagtt aatagtacac tactacaaat
    19261 tggacaagtt ttgatagaag ctaccaacat tagccctata ataatgggaa ttatactagg
    19321 aggtctaata acagtagttg gaacgtctcc acttagttca atggctctta catctataat
    19381 tggtcttact ggtcttccta tggcaatagg agcattaggt gcttttggtt cagcttttat
    19441 gaactcaaca ctatttgcaa aattgaaatt aggttctaaa aaagatatta tatctgttgc
    19501 tattgaacca ttaacccaat cagacataat ttcagctaat ccaataccta tatattctac
    19561 taatttcttt ggaggagcct tttctggtat cattgtagcc ttgatgggtc ttgtaaacat
    19621 gacaccaggt acagctacac ctgtggctgg ttttgctata atgtttgctt ataatccagt
    19681 tcaacaagtt cttataacag ctggtttatg tgctttattc aatgtaattg caggattttt
    19741 aggttcaaaa atattcagta cctttaaagt tcttactgct ggtgaaatac gtggtactga
    19801 tgtagaagaa gaaattgctt aaaaaacaat aagatttata aatttatatc tcaagtagta
    19861 gagttttata ttgtaggcaa ttttattaat tgcaaacgtt ttatttttta tttatgttta
    19921 tgattattat gtgtgttgaa tatttagata aatttttatt tattattttt atttagattt
    19981 ttgtttagtt ttttatttgg ttgatatatt aggaataaaa attagtatag tttattacta
    20041 gttagatagc ataacttttt agatacataa aaaattttat attaattaga tattattaaa
    20101 ataaaagcga tacatgaatt tttaaatgtc catgtatcgc tttatttttg ccataatctt
    20161 aacaactgat ttttaaagtt tattatctta acaaagttca ttatcttata taatatttaa
    20221 atgcatagac ttctttaatt taaccatcta aatatttaat taaatattat tatatgtaat
    20281 ataactaatt tttaaatgaa tgtataggag ctggaatcct tcctcctctt tgagtaaata
    20341 attcagatga atttgtattt ataggcatta ctggtgctcg tcctaaaagt cctccaaatt
    20401 ctaccatatc acctacatca catcctgggg ctggtataat tctaacggct gtagtcttat
    20461 tattaatcat acctattgct gcctcatcag ctatcatggc tccaagcgta cctgctgtag
    20521 tatttcctgg cacagctatc atatcaagac ctacagaaca aatagcagtc attgcttcaa
    20581 gcttatctat acttaaagca cctttaataa cagcatcaat catacctgca tcttcagata
    20641 ctggtataaa cgctccacta agtcctccaa catgtgaaca tgccattact ccaccttttt
    20701 taacagcatc atttaaaagt gctaatgctg ctgtagtccc atgagtacca acaacttcaa
    20761 gacccatttc ctctaatata tttgctaccg aatcaccaat agcaggtgta ggagctagtg
    20821 ataagtctat tatcccaaat ggaacatcca atctactaga agcttccttt gccacaagtt
    20881 gtccaactct tgtaatttta aatgcagtct ttttaactgt ttctgaaaca acatcaaaag
    20941 gctctccctt tactttctct aaagctctct taacaacacc agggccactt acaccaacat
    21001 ttataattct atcagcctca ccaacaccat ggaaagctcc tgccataaat ggattatctt
    21061 ctactgcatt acaaaatact actaattttg cacaaccaaa accttttgca tcttttgtta
    21121 attctgcagt ttcttttatg atttctccca tttctttcac tgcatccata tttataccac
    21181 atcttgtaga acctacattt actgaagcac atactttatt agtacttgct agagcttttg
    21241 gaattgactt aattagtatc ttatcacctt ttgtatatcc cttttgaact aatgctgaga
    21301 atccaccaat aaaatctata cctaaatctt ctgcagcctt atccaatgtc tgtgcaaact
    21361 ttacatagtc attttcatct gttgcacctg caataatgga aattggagtt actgataccc
    21421 ttttatttac aattgggata ccaaattcac gctctatatc ttttccaacc ttcaccaaat
    21481 ctttagcaga actcataatc ttattgtata ttttttctct agctttatct ccatcagggt
    21541 ctatacaatc taataaagaa atccccatag ttatagttct tatatccaac tgttcttcat
    21601 ctatcatctt tattgtttca agtatatttc ctacattcac tattatcacc tccccttact
    21661 gtctactaca gattatgcat tgaattaaat atttcttctc gctgaatttt tacatccact
    21721 gataatttct tacctctttc aaccaagtcc tcaaccgttt tctcaaaaga atttaatgat
    21781 ttctctaaat caactatcat aatcatagta aaataatcct gtaatatttt ttgtgatata
    21841 tctactatgt tgatattttg cttgtataat tcatcactaa ttcctgccac tatacctggt
    21901 ttatcctttc caattactgt taaaattgct ttcataataa tatcctccct tattttttta
    21961 taaatcttat atttttacaa attgaactat gtgttaacat atatttcatt tatttgttag
    22021 taaaccact
//
LOCUS       DAJMZY010000067        22028 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.067, whole genome shotgun sequence.
ACCESSION   DAJMZY010000067 DAJMZY010000000
VERSION     DAJMZY010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 22028)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22028)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22028
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.067"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            <1..819
                     /locus_tag="OE968_002421"
     CDS             <1..819
                     /locus_tag="OE968_002421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HCP7219697.1"
                     /translation="TFFISCFALILFMEGTKYIQLRLGYSFLLEGVLNIILFLVLIIL
                     SFYTGFKVIRLINNNNEQEYKLQKLDSKINHKDNIIIKLRSQKHDYLKHLQVVYSLLN
                     TGLDEDAKEYIMNISNSFKSKNSRYGKVSYLDAIASLKYEECLEKDISFDVYIQDFMD
                     NLEIEPNDMSSVLLNIIDNAIESLSTIKKEKKYIRVHAYEDEFQYIIAIKNNGPKIHN
                     VESIFWNGFSTKEGQDRGYGLHLVKNILDKYDYSILVNSDDFLTEFVILIPKYY"
     gene            838..1575
                     /locus_tag="OE968_002422"
     CDS             838..1575
                     /locus_tag="OE968_002422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCP7219698.1"
                     /translation="MIKVLICDDDKIVRDDIANIAKESGYVDYVKKVKDGIEAIEFIK
                     NEKIDLLIIDIDMPYKNGIDSAEEILSIDKDIHIVFVTGFADYSLESFKVHPIDFVVK
                     PFKKEKILDSINIAIDHINSHKIANNNFIEDTLFVYKIRKQIHMINFDDIVMFEKNSR
                     AINLHTKDEDIIKFYENFDDLKKRLPPNFFMTHRQYIVNLRFIHKVIPINKSSLEIRF
                     INFQENAILNKSLEKDFLYRFYRVKRF"
     gene            complement(1761..6818)
                     /locus_tag="OE968_002423"
     CDS             complement(1761..6818)
                     /locus_tag="OE968_002423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4132 domain-containing protein"
                     /protein_id="HCP7219699.1"
                     /translation="MLERTRVEKNPKIIENFKNNFTKSSSKQYYDLAKSLWDCIENSS
                     YYYREPEDKFLNMIKKYYNCHYYEIKNMDELLSGPLKNALELIFTSEQVEELCQLIKR
                     KMDYTYSGGYYRKGYRSNKLVDYFRGIIRFISNYVDLIYYDFSVIDYLTLPNKVLYYD
                     SIMSDKIALEIDKGNQKVISALEEVIFGENQTALLTRQMIIGIMKSHSDKCYEMLSKL
                     LLAAKQQEGLRQQIVESLDEGTISASIYMLKTILDNNLERFSSVIRALDTWTGLGFSD
                     QKPGIIRKCLELSYKSLTDEKFRIESINSNDNLEIYFALWATATYNIYDSYSLIENLL
                     SCQEKYKKLVALYFLSHTESTYFKHSIASKNIKGDDLEILAWVITNFYVEGSVGYYYS
                     WQNRETNFDLSNTPIDKDFDARKEQFESLKHTLEILNSKTKSFSGSVFPWTWIEISSH
                     EILKCMMTLTAYDMNAQFIDVLMENCHLMSSDLRASLIVNFVNEPKTDRQREFLLECL
                     SDKSVSNRETVLSLLRKLELTDVELDKITNLLSLKTSSIRQTVIKILLEQDDSNLENI
                     ASSLIKSSNSQKCLGGLEIVNLLKDNTARQELYNKLVLLIEDIDKSKKNTSQVQILID
                     NLLGKAKNDYCKENGFGIYNPENKVQIPEQFDFKDDSNSSSKLNKIISNISLSTREDS
                     VSVATKKEAKKILDTDINKIIKVYEKFDELITENADYEYEVERWSGNVDKVLLGYSTY
                     NLTPIKYKVSNDTLDNYPLAELWRETSKKLDLDYKLILDILFYSISTCGYNETEKSWF
                     SSIYSNVLDSKKQNKIYTKLEKLKFNGLTRKLLRVLLNEFDHKEIFNYCLEIYYKLRN
                     LLTIEQCKKQRVEFTKNYYRQNEYCPALNAPILNYWLDKAHSFIYDDISFTKFFYTTF
                     SNYQLLEYKFPFYTSINVFARAHELGLMTEEQVNREMISGYNASNIIRTLTNPRWAGD
                     TLEKYPWLKDNLKTVTNRIIEIESRRGDMPTEVSHLANNIQYFEGINYFVNILVALGK
                     ETFQRGYSYGSNYSKKDVLSSLLKNCYPTKEDDSKKLKSLLKNTDITELRLIESAMYA
                     PQWVNIIEKYLNWKGLKSTIWYFHAHINEGFSAQKESEVALFSPISPRSFIDGAFDVD
                     WFLDSYKTIGEERFNILYKSAKYITSGGNSHRRAQLYADATLGKLDKDMLMKEIETNR
                     NQDKLRSFSLLPMKKGDLKEATFRYEFIQKFAKESKQFGAQRRESESKACTIALENLA
                     RSAGFGDVNRMMWALETEKLNEVAHLFKPKDIDGTSIWIDVDENGKASTKVQKGNKSL
                     KSIPKAIAKHPYVLELKSVQKDLKSQYSRAKQSLEQAMKNEIVFTVKEIANIYKNPVI
                     CPLIKNLVWVCDDNIGYVYNDKSKFFICNIEGETYKLTAKNKLKLAHPVHLFESGKWS
                     EFQHDLFSKQIVQPFKQVFREYYRINSDELSEKTISRRYAGHQIQPKKTVALLRNQLW
                     TVDYEEGLQKVFYKENIVAKMFALADWFSPADIEPPTIETVEFFDRKTYKSLELASIP
                     PILFSEVMRDIDLVVSVAHAGGVDPETSHSTVEMRIAIAKELLLLLKINNVNFEGSHA
                     LIAGNLGEYSVHMGSGIVHKKGMGALNILPIHSQSRGKIFLPFADEDPKTAEIMSKIL
                     LLAEDSKIKDPSILSNL"
     gene            complement(6843..7262)
                     /locus_tag="OE968_002424"
     CDS             complement(6843..7262)
                     /locus_tag="OE968_002424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219700.1"
                     /translation="MQIYFRVKAVGKRKPMLELTPFDVSDNINCLKEAISEIVSKNVL
                     EYNEKIPEKSIINFLTNEEIESQADIGKVGFGSIYNENKQSVEKAIEVALQAFEDGIY
                     KVLINEDVIEKLDSSINLKSGDIFTFIRLTLLAGRMF"
     gene            complement(7496..7747)
                     /locus_tag="OE968_002425"
     CDS             complement(7496..7747)
                     /locus_tag="OE968_002425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219701.1"
                     /translation="MNRYTKIINMMGSYYTKDFEKEKKNVIKVREVKEDTVRKFFLQG
                     DCEVLVVFEDTGKEILIDDFSPEEDIKKYLGAKFINKKR"
     gene            7836..8567
                     /locus_tag="OE968_002426"
     CDS             7836..8567
                     /locus_tag="OE968_002426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkgJ family cysteine cluster protein"
                     /protein_id="HCP7219702.1"
                     /translation="MTSIKNKDILNCIDYSIKNKLFDKLNDVYKSLPVGNCSGCGNCC
                     MESVGINLIEFLNIFCYLEDRVDLKKSCISKILDYYFEEYTRKNPCPFKDTNNRCLIY
                     EVRPLNCRMFGHWKKEDYNKNLDNVIEKNNNYRELMKKQYGFEINDEVVNYRIDYCDR
                     FIPNKDYLSKSKRLSFFDELMILDSNIYSSGNIDIDFRDRGIVEYFIESLLYRNLAYN
                     VKIRISKEYKIRKRTIDRIKRIVLV"
     gene            8626..9537
                     /locus_tag="OE968_002427"
     CDS             8626..9537
                     /locus_tag="OE968_002427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HCP7219703.1"
                     /translation="MNLTKVKGNTFFIKGGTNTGIYVFEDNTALMIDPGLCGSRPRRV
                     NKVLDENNIQVRYIINTHGHDDHYGACNQFKEYYKDVCIMSSEYDKLYIENPELFSKY
                     IVGGKSNVFMDNILKNKMLDDIKIDKFIEAGKFELNNEMFDIIEFQGHTPGSIAVLTK
                     DNVIFVGDLLIGDEILSKYDFLFLYDIQEQINSLEKLKNIDFEYLVLGHGKQVISKED
                     SYKLIEKHLNALKKYLYQIRELLVEPKSLEILLKNIINNNNLSNNYKEYHFFKSSLVS
                     VISYLVDLEEIGYILENGELLYYTKTK"
     gene            9588..10400
                     /locus_tag="OE968_002428"
     CDS             9588..10400
                     /locus_tag="OE968_002428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HCP7219704.1"
                     /translation="MEYEKWNEILAPYEHAVEELKIKFKNIRKEYLAKGEYSPIEFVT
                     GRTKKISSIISKLKRINAKDIETEIDDIAGIRIMCQFVEDIYAIVDLIKVRNDMTIIG
                     EKDYITNYKDSGYRSYHVIIKYPINSIAGSKEIICEIQIRTLAMNFWATIEHSLKYKY
                     DHYIPETLAERLRRASDAAFLLDQEMSEIREDIMKAQAMYQMKSIAIRDTLNRIQELY
                     DLGDTHKAMQYQRKLDRTETDKNITEILELKQEIDILLEQYKDTKVDDKVVQ"
     gene            10509..11201
                     /locus_tag="OE968_002429"
     CDS             10509..11201
                     /locus_tag="OE968_002429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HCP7219705.1"
                     /translation="MSLYAIGDLHFSTSVNKPMNIFGSNWDGHEKKIIDNWKEVVKEE
                     DMVLVLGDTSWGINLSEAKKDLDIISKLPGQKILIKGNHDYWWTTVTSLNKLYEDMRF
                     IQTNFYEYKDYAICGGRGWICPNDVKFDETDEKVYKREEHRLRLSLESARKSGHSKII
                     VITHYPPTNDKLEESLFTKLFEEYNVEKVIYGHLHGKESFKMGLKGIRNGVEYTLASC
                     DYTEFNLIKVHD"
     gene            11288..12229
                     /locus_tag="OE968_002430"
     CDS             11288..12229
                     /locus_tag="OE968_002430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219706.1"
                     /translation="MRWILVFIFLYLIPLVVIFRNYKNFKRSCIYSSIYVVLATTIMI
                     SNIYMSGLNKIKESMYYHNYISDETYDEKYVSNFKEKESTDLNQDNKKNEEISNNKNL
                     NNKQDRNIQNKESNEEGSNDIKEKNNSDSNVSVNNKSEKQEDNTKENNKYTSKEKNSE
                     DIKKIDMESIGIFKKEIYNIERAALVPMRECIPYTKDIAKNITKLSSIKKDVTNARNK
                     CKEVVKEYENMQIPELSKEKYTETLSNARDDVKKAYELREKSMESALKLINTKSPKYI
                     GKITEYLDLSDKQIESFKNRLNDLKEEINNSETNNIN"
     gene            12266..13423
                     /locus_tag="OE968_002431"
     CDS             12266..13423
                     /locus_tag="OE968_002431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase"
                     /protein_id="HCP7219707.1"
                     /translation="MNKQSIGKLNMFFMGITQRNLDNRDFFIELEVIFKSGRKEFKGI
                     AIEEDNKYKFNFKGKSDLYTFNELLKNISKEAENYDGLVFKYVERGTIVVIEGDNKKV
                     NVKYLDNKEEVPKIDEFTASQIKNRDYYVKVGQANALLKEIGVLTKDGKIKNDKIRKY
                     NQIDHFVELIDSILKEIKDKDCITILDCACGKSYLSFVLNFYIKEVLKKNCYFIGIDY
                     SDVVIEASKNMAKNLGYKNMSFIKEDLTNYTPNRDVDLVISLHACDTATDMAIGLGIR
                     AKSEAIVVVPCCHKELLGQYRYEAMEPILKHGVFKARFADLITDGLRTLLLEGNGYDT
                     SVVEYISPLDTPKNLMIRAIKTKTNNDKALKEYKELKSQFGVEPTLEKLIY"
     gene            13575..14135
                     /locus_tag="OE968_002432"
     CDS             13575..14135
                     /locus_tag="OE968_002432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HCP7219708.1"
                     /translation="MNKLNICIDIDGTITSPYHFLPYLNDIFNKNITEAECITHNWEE
                     LYGSGIRDVYAEFNNKYIHSYDEAKIVEGATEVISTLSKGHNLSFVTARHECLTDVTK
                     NWLSRQGFSDIDVYLLGSDYKVEKARELSCDIFIEDNPLNSVQLADDGVKVILLDTNY
                     NKDVKHQNIVRVSNWIDIEKIIKQGI"
     gene            14163..14654
                     /locus_tag="OE968_002433"
     CDS             14163..14654
                     /locus_tag="OE968_002433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219709.1"
                     /translation="MIDLKIENRKGKIHVKSSEIKDILELRPDFEYVQDISNTINQEN
                     ILVFDCQLTGNSFDMDDLDIEEILEELGEEIDESYFSVLFEDVRAYLKDATDEIEADL
                     QDNYLFDNLRCYFDIYNINQEFTDFKFVFLVSFKDIKISSLANLAKIVSKRQLIGASK
                     FYS"
     gene            14883..15434
                     /locus_tag="OE968_002434"
     CDS             14883..15434
                     /locus_tag="OE968_002434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCP7219710.1"
                     /translation="MQSLNEIIAENLKKIRKEKHLSLDKIAQLSGVSKSMLSQIEKCE
                     VNPTISTLKKITNGLKISFTSLMERQESDIELIQKSDIDHFIEDNGKYISYPIFPFDS
                     KRRFEIFMIEIEEGGNLDSNAELPGTQEFITVFSGEVTIKINGEDYIVSSGNSIRFKA
                     DVSHIYRNSGKGIAKMSMVVYYI"
     gene            15520..16452
                     /locus_tag="OE968_002435"
     CDS             15520..16452
                     /locus_tag="OE968_002435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacyl-tRNA deacylase"
                     /protein_id="HCP7219711.1"
                     /translation="MNNKKAVFFFCSDLKKDPVASNVIKCCEEIMDLNQTDIVIDDNF
                     VLEFKDKNNNLFHFVKTKDVISHNYKYYLPILNRHFRDYDFAGVVNWHEGENAPEHIL
                     TAHTIGDVPTGEFGNSNPRYFKNLINAIEDIKNENLLDEFTTLTEATHWSGTTYGEES
                     KLITEYSVPMLDIEIGSSSDSFNNSIAIQVLAKSLIRVFDCDEPLKTLLCVGGVHFEK
                     SFSDIIKNKEYNISIGHVLPNQWIVSGMYDDESGFEKLEKCINSIEGGIDCIVFHDKL
                     KGTYKEQCRKLGEKLNVPVFKHKILKNPKDLPIW"
     gene            16507..17370
                     /locus_tag="OE968_002436"
     CDS             16507..17370
                     /locus_tag="OE968_002436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HCP7219712.1"
                     /translation="MILSYFALLIRVVLLAFERVVVRLLGDEEGDIYKNIASSFLFFF
                     IGGVCLLPFSIMDRVSDWSFLIPCYISSLVYSIGSVAYVTSLATGEVSLVTPINSLNS
                     LFLLLLSVIFLGEGLSLAKVAGIIIMIGGVFILKKVSSFLKNVSVIFNNLPCRLMFLY
                     IFLQSVGRVLDKAFFVQVSPILYSTILYFFVGLNLFIFLAFKKKQKIICEIFSNKKGL
                     SILSGAINGYSYLALLIALNNLELSIAEPFSQVSMIITLILAHFIFKENIKEKIPGSI
                     LILIGGWLLLL"
     gene            17617..19479
                     /locus_tag="OE968_002437"
     CDS             17617..19479
                     /locus_tag="OE968_002437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HCP7219713.1"
                     /translation="MNYKKTAIDIIEQVGGSKNILALEHCSTRLRFKLIDRSKVNQDA
                     LKKVQGVMSIVNGAQFQVVIGNSVVDVYDEILKVCPLDTNDSTVKTEEKINLGTRFIE
                     FIINIFQPLIFAIAGAGILKSLLMLLAMFNILKSDSTIYTLLVAISDATFYFLPLMVA
                     VTTANVLKCNRLVAIAAVGYLLLPATTTALSEGVELFGFTIPNIAYNAQVFPAILCVS
                     FLATMEKIFNKYSPKPIRTFFVPMMSLAITVPITLTILGPLGYNVGTIFTTIILFLYN
                     KMGFLVVGLLAAFLPFMVATGMHKALIPYSINTIGKLGYEALYMTSSLAHNISESGAC
                     FAVALRTKDETLKQTALSAGISALMGITEPALYGITLQHKRAMLGVVFSSAISGTFLG
                     LFAVKGFVIVGPGLASMSMFIDPNNGNNLIFASIGFVIAILGSFIITLIIWKEDTNTV
                     ESSIGDVVEEELEEEKEVNILVTPVEGKVIDLSKVNDELFASKTLGDGVAIIPTNGNL
                     YAPCDSEVVMLFETKHAIGLRTKNGAEILIHIGINTVSMNGDGFKTFVKTGDNVKEGD
                     LLIQFDLDKISHANLDSTVMIVNNNGADYAYKVLNQSYGNVKKGSILFDVKGGI"
     gene            19482..20948
                     /locus_tag="OE968_002438"
     CDS             19482..20948
                     /locus_tag="OE968_002438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000110363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HCP7219714.1"
                     /translation="MRKFPEGFLWGGATAANQFEGGWNLGGKGWSVSDVAKAHFDADV
                     KDYKSNNEITTKDIEEGLAHPEDEVNYPKRHGSDFYHHYKEDIALMAEMGFKTYRMSI
                     AWSRIFPNGDDKEPNEEGLQFYDDVFDELISYGIEPLVTMSHYEPPLNIVLNYDGWYS
                     RQVINMFVRYVETICERYKNKVKYWLTFNEVDSMIRHPYTTGGLVRDRFKDKNFEEVI
                     FQAMHHQFVASALATKICHEIIPNSKVGCMLTKLTYYPYTCRPEDVLATQRKMRSIYA
                     YSDTQVFGEYPVYLLSYFKNNNIQIVKEEHDDEIMKKYPVDFISFSYYMSSCEAADTT
                     GLDITPGNTLLAVKNPYLEMSEWGWQIDSIGLRISLIELYDRYRKPLFIVENGLGAKD
                     ILTEDKKVHDQYRINYLKEHFKCMLDAIIEDGVELWGYTSWGCIDLVSESTKQMSKRY
                     GYIYVDADDYGKGTYNRYKKDSFYWYKKVIESNSIDFK"
     gene            20972..21808
                     /locus_tag="OE968_002439"
     CDS             20972..21808
                     /locus_tag="OE968_002439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HCP7219715.1"
                     /translation="MNYIIKKVLNSSVVLVHDTKDNEFILLGKGIGYGKKTGEYICGS
                     NDNQMFVPVENTKSKQFLELMDDIPVDILKITQEIIVEAEKLLNSSFNKNLYLILADH
                     FNFAIERMRKGIKITNRVFWEIKNYYPNEFKVGMVAIYMVEERLGIQLPEEEAANIAF
                     HFANAMASDGNSYDTIKYAKVIGEIINIFVFSLNRTLDKKSMHYMRFITHIKFFVERF
                     FSDSMLSSGDDLLFNQMKRSNPKEMLIALKVRDFLEKKYGKKLTNEEIAFLVVHIARV
                     KQ"
BASE COUNT         8297 a         2480 c         3612 g         7639 t
ORIGIN      
        1 acatttttta tatcgtgttt tgcattgatt ttatttatgg agggcactaa atatatacaa
       61 ttaaggttag gatatagttt tttacttgaa ggagtattaa atattatact ttttttggtt
      121 ttaattattt taagttttta tacaggcttt aaagttataa gattgataaa taataataat
      181 gaacaggaat ataaactaca aaaactagat agtaaaataa atcataagga taatataatt
      241 atcaaattaa gaagtcaaaa acatgactat ttgaaacatt tgcaagtggt gtattctcta
      301 ttaaatactg ggctagatga agatgccaaa gaatatataa tgaatatatc aaatagtttt
      361 aaatcaaaaa attcaaggta tggaaaagta tcttatttag atgctatagc ttcattaaaa
      421 tacgaggaat gtcttgaaaa ggatatatct tttgatgtct acattcaaga ttttatggat
      481 aatttagaga ttgaacctaa tgatatgagt tcagtactat taaacataat agataatgca
      541 atagagtctt tgtctactat aaaaaaagaa aagaagtata taagagtaca tgcatatgaa
      601 gatgaatttc agtatattat agctataaaa aataatggtc ctaaaataca taatgttgaa
      661 agtatatttt ggaatggatt tagtactaaa gaaggacaag ataggggata tgggctacat
      721 ttagttaaaa atatattaga taagtatgat tatagtatac ttgtaaatag tgatgatttt
      781 ttaactgaat ttgtaatctt aatcccaaaa tattattagt taggaggaga aaagtctatg
      841 ataaaagttt tgatttgtga tgatgataag attgtaagag atgatatagc aaatatagct
      901 aaagagtctg gatatgtaga ttatgttaaa aaagttaagg atggtataga ggcaattgaa
      961 tttataaaaa atgagaaaat agatttattg attattgaca ttgatatgcc atataaaaat
     1021 gggattgatt ctgctgaaga aattctttct atagataagg atatacatat agtatttgtg
     1081 acgggtttcg ctgattatag tcttgaaagc tttaaagtgc atcctataga ttttgtagtt
     1141 aaaccattta aaaaagaaaa aatacttgat tcaattaaca tagcaataga ccatattaac
     1201 tcccataaga ttgctaataa taattttata gaagacaccc tttttgtata taaaataagg
     1261 aagcagatac atatgattaa ttttgatgat atagttatgt ttgagaaaaa ttcaagagca
     1321 attaatctac acactaaaga tgaagatata ataaagtttt atgagaactt tgatgattta
     1381 aaaaaacgcc tacctcctaa tttctttatg acccatagac aatacatagt aaatctaaga
     1441 tttatacata aggttatacc tataaataaa tcttcattag agataaggtt tataaatttt
     1501 caagaaaatg ccatattaaa caaatctcta gaaaaagatt ttttatatag attttatagg
     1561 gttaaaagat tctagtgaag atagaagaaa aatacttttt gtgtgatata ataagtacca
     1621 taaagataat gtataagaga agtttatata aaaattattt gtaattatga tttaatctat
     1681 ataaattaca gtatagtata tattggactt tctaattttt tttaagaaag tccaatatat
     1741 tttagggata gtttttatac ttataaatta cttaagatac tagggtcttt aatcttacta
     1801 tcttcagcaa gtaatagtat cttagacata atctcagcag ttttagggtc ttcatcagcg
     1861 aatggaagga atatcttacc tctactttga gaatgtatag gaagtatatt caaagcaccc
     1921 atcccttttt tatgtacaat accagaaccc atatgcacag aatactcacc taaattacct
     1981 gctataagag catgagagcc ttcaaaattg acattgttaa tttttaataa taataaaagt
     2041 tctttagcaa ttgctatacg catctctaca gtagaatggc tagtttcagg gtcaacacca
     2101 ccagcatgag cgacacttac aacaaggtct atatcacgca taacttctga gaatagaatt
     2161 ggaggtatag aagctaattc taaactttta taagtttttc tatcaaaaaa ttctactgtt
     2221 tcaatagtag gaggctctat atctgctggt gaaaaccaat ctgcaagtgc aaacatcttt
     2281 gccactatat tttctttata aaatactttc tgtaatccct cttcataatc gacagtccaa
     2341 agctgatttc taagaagtgc tacagttttc tttggctgaa tttggtgacc agcatatctg
     2401 cgagatatag ttttttcaga taattcatca ctgtttattc tataatactc acggaatact
     2461 tgcttaaatg gttgaacaat ttgcttacta aataaatcat gttggaactc actccactta
     2521 ccagattcaa acaaatgaac tggatgtgca agttttaatt tattttttgc cgtcaactta
     2581 taagtttcac cttctatatt gcaaataaag aacttagact tatcattata aacatatcca
     2641 atattatcat cacataccca tactagattt ttaatcaaag ggcagataac tggattttta
     2701 tagatattgg caatttcttt aactgtaaat actatttcat ttttcatagc ttgttctaaa
     2761 ctctgttttg cacgagaata ctgactcttt aaatcttttt ggacagattt aagttcaagt
     2821 acatatggat gtttagcaat agcttttggt atactcttta aagacttgtt gcctttttga
     2881 actttagtag atgcttttcc gttttcatca acatctatcc aaattgaagt accatcaata
     2941 tcttttggtt taaatagatg agcaacttca tttagttttt cagtctcaag agcccacatc
     3001 atacgattta catctccaaa tccagcactt ctagctagat tttctagcgc tatagtacaa
     3061 gcttttgatt cactttcacg acgttgtgca ccaaattgct tgctttcttt agcaaacttt
     3121 tgaataaatt cataacggaa agttgcttct tttaggtctc cttttttcat aggaagtaaa
     3181 gagaaacttc tcaatttatc ttgatttcta tttgtttcaa tttctttcat caacatgtct
     3241 ttatcaagct taccaagtgt agcatcagca tagagttgtg cacgtctatg agagttacca
     3301 ccactagtta tatatttagc tgacttgtaa agtatattga atctttcttc cccaatagtt
     3361 ttatatgaat ctaaaaacca atctacatca aatgcaccat caatgaaact acgtggtgaa
     3421 ataggggaga atagagcaac ctctgattct ttttgtgcag agaagccttc atttatatgt
     3481 gcatggaagt accaaattgt acttttcaga cccttccagt ttaaatattt ttcaattatg
     3541 tttacccatt gaggggcata catagcagat tctatcaatc ttaactcagt aatgtcggta
     3601 tttttaagta aactttttaa tttttttgag tcatcttctt tagtaggata gcaattttta
     3661 agtagagaac ttaaaacatc tttttttgaa taattgctac catatgaata tcctctctgg
     3721 aacgtttctt taccaagagc gaccaaaata tttacaaaat aatttatacc ttcaaagtat
     3781 tgtatattat tagctagatg agacacctct gttggcatat cacctctacg tgattcaatt
     3841 tctataattc ggtttgtaac agtttttaaa ttatctttaa gccaagggta cttttctaat
     3901 gtgtcgccag cccatctagg atttgtcaat gttcttatta tatttgatgc gttgtatcca
     3961 cttatcattt ctctattaac ttgctcttca gtcattaatc ctaattcatg tgcacgagca
     4021 aacacattta tgctagtata gaaaggaaac ttatattcta gcaactgata atttgaaaac
     4081 gtagtgtaga aaaacttagt aaaagaaata tcatcataaa taaacgaatg tgctttatca
     4141 agccaatagt ttaaaatagg ggcatttaaa gcagggcagt attcattttg tctgtaatag
     4201 tttttagtaa attcaactct ttgtttttta cattgttcta tagtcaataa gtttctaagt
     4261 ttatagtata tttctaaaca atagttaaat atttctttat ggtcaaactc atttagtaaa
     4321 actcttaaaa gttttcttgt aagtccatta aatttaagtt tttcaagttt tgtatatatt
     4381 ttattttgtt ttttagagtc aaggacattt gaatatatag atgaaaacca acttttttct
     4441 gtttcattat atccacatgt acttatacta taaaataaaa tatcaagtat taatttgtaa
     4501 tctaagtcaa gctttttact agtttctctc caaagctctg ctaatggata attatcaaga
     4561 gtatcattag aaactttata tttaatagga gtcaagttat aagtagaata acctaaaagt
     4621 actttgtcta cattacctga ccatctttca acttcatatt cataatctgc attttcagta
     4681 ataagctcat caaatttttc ataaactttt attattttat ttatatccgt atcgagaatt
     4741 ttttttgctt ctttttttgt tgctacagaa acagaatcct cacgagtaga taaacttata
     4801 tttgagataa ttttattaag ctttgatgag ctattagaat catctttaaa atcaaattgt
     4861 tctggaattt gaactttgtt ttcagggtta tatattccaa aaccattttc tttgcagtaa
     4921 tcattttttg ctttacctaa caaattatca attagtattt gaacttgaga tgtattcttt
     4981 ttagatttat caatatcttc tataagtaaa acaagcttat tatatagttc ttgtctagca
     5041 gtattgtctt ttaataagtt tacaatttca agacctccaa ggcatttttg agaatttgaa
     5101 gattttatca gtgaagaagc aatattttcc aaatttgaat catcttgttc aagtaaaatt
     5161 tttattactg tttgtctaat agagcttgtc tttaaagaca atagattggt tatcttatct
     5221 aattctacat ctgttagctc aagctttcta agtagactca ataccgtttc tctattggaa
     5281 acactcttat cacttaaaca ttccaataaa aattcacgtt gtctatctgt ctttggttca
     5341 tttacaaaat tgactataag tgaagctctt aaatctgaac tcataagatg acaattttcc
     5401 ataagcacat ctataaattg agcattcata tcgtatgctg ttaaagtcat catacattta
     5461 agtatttcat gagaagaaat ttcaatccaa gtccatggaa atacacttcc tgaaaatgat
     5521 tttgtctttg aatttaaaat ttctaaagta tgttttaaac tttcaaattg ttcttttcta
     5581 gcatcaaagt ctttgtcaat aggagtgttt gacaagtcaa aattagtttc tctgttttgc
     5641 caactatagt agtagccaac agaaccttct acatagaaat ttgtaattac ccatgctagt
     5701 atctctaaat catcaccctt aatgttttta gatgctatag aatgtttaaa atatgtactt
     5761 tctgtatgcg ataaaaagta aagagctaca agttttttat atttttcctg acaagaaagt
     5821 aagttttcaa taagagagta agagtcatat atgttgtaag ttgcagtagc ccataaggca
     5881 aaataaattt caagattatc attgctatta attgattcta tacggaactt ttcatcagtc
     5941 aatgatttat atgaaagttc taaacattta cgtattattc caggtttttg gtctgaaaaa
     6001 ccaagtcctg tccatgtatc caaggctctt ataacagaac taaatcgctc taaattgttg
     6061 tccaaaatag tttttaacat gtatattgat gcagaaattg taccctcatc taaactctct
     6121 acaatttgct gtctaagtcc ttcttgttgt ttggctgcca aaagaagttt agaaagcatt
     6181 tcatagcatt tatcactatg actcttcatg ataccaatta tcatttgtct tgtaagtaga
     6241 gcagtttgat tttctccaaa tattacttct tctaaagcac ttattacttt ttgatttcct
     6301 ttgtctattt ctagtgctat tttatcactc attatagagt catagtacaa gaccttattt
     6361 ggaagagtaa gataatctat aactgaaaaa tcataataaa ttaaatcaac atagtttgaa
     6421 ataaacctta taatacctct aaaataatcc acaagtttat ttgagcgata ccctttacga
     6481 taatatcctc ctgaatatgt ataatccatc tttcttttaa ttaattggca aagttcttct
     6541 acttgttcag aagtaaatat taattctaat gcatttttta aaggtccaga aaggagctcg
     6601 tccatatttt taatttcgta gtagtggcaa ttgtagtatt tctttatcat atttaagaat
     6661 ttgtcttcag gttctctata atagtatgaa ctattttcta tgcagtccca aagagacttt
     6721 gctaagtcgt agtactgttt tgaagaagat ttagtaaaat tatttttaaa attttcaatt
     6781 attttaggat ttttttctac tctagtacgt tctaacattt atgtacctcc aaattattta
     6841 ttttaaaaca ttcttccagc aagcaaggta agtcttataa aagtaaatat atctccactt
     6901 ttcagattta tagaggaatc gagtttttca ataacatctt catttataag cactttgtag
     6961 attccatctt caaatgcctg taacgctacc tctattgcct tttctacaga ttgtttattc
     7021 tcattgtaaa tagagccaaa tccaactttt ccaatatcag cttgagattc aatttcttca
     7081 ttagttaaga agtttattat tgatttttct gggattttct cattatattc aagaacattt
     7141 ttagatacaa tttcagagat agcttctttt aggcaattga tgttgtcaga tacatcaaaa
     7201 ggggtaagtt ctagcatagg tttgcgtttg ccaacagcct taactctaaa ataaatttgc
     7261 ataaaatcac ctcgcaaaat attaattatg tatttagaaa tttaaaaatt tatctatttg
     7321 ttatattata tcattttgtg aattattaat gtgaattatg gaattatttt acaaaaaata
     7381 gaaaaaaagc tatcttaaag tctaaaaaag caataaaaga taacttttaa ctataattat
     7441 atagaattat aactgtacat ttattaaatt ttaattttag aattattttt gataactatc
     7501 tttttttatt tataaatttt gctcctaaat attttttgat atcttcttca ggagaaaagt
     7561 catcaataag tatttctttc ccagtgtctt caaatactac aagaacttca cagtcacctt
     7621 gtaagaaaaa ttttctaact gtatcttctt taacttctct aacttttatt acattctttt
     7681 tttctttttc aaagtctttt gtgtaataac ttcccatcat attaattatt tttgtatatc
     7741 tattcataaa atacctccat atgcgattaa atttaaaaaa tatgttataa taattgtttg
     7801 tattaactta ataattataa caaggagtaa taataatgac tagtataaaa aataaagata
     7861 ttttaaattg tatagattat tccattaaaa ataagctctt tgacaaacta aatgatgtat
     7921 ataagtcctt gccagtagga aattgttctg gatgtggaaa ttgttgtatg gagtcagtag
     7981 gtataaattt aattgagttt ttgaatatat tttgttatct tgaagataga gttgatttaa
     8041 aaaaaagctg tataagtaaa atattagatt attattttga ggagtataca agaaagaacc
     8101 catgtccatt taaagatact aataatagat gtttaatata tgaagttaga ccattaaatt
     8161 gtaggatgtt tggacattgg aaaaaagagg attataataa aaatttagat aatgttattg
     8221 agaaaaataa taactataga gagttaatga aaaagcaata tggatttgaa ataaatgatg
     8281 aagtagtaaa ttacaggata gattattgtg atagatttat tccaaataaa gattatttaa
     8341 gtaaatctaa gagattaagc ttttttgatg agcttatgat attagactca aatatttatt
     8401 caagtggaaa tatagatata gactttaggg atagaggtat agttgaatat tttatagagt
     8461 cattacttta tagaaattta gcatataatg tgaaaataag gatatctaaa gaatacaaaa
     8521 taagaaaaag aactatagat agaataaaaa ggattgttct tgtatagttt tatattagta
     8581 agtaataaat tgtatcataa atattgtcaa aatgaggtga agaaggtgaa tcttacaaaa
     8641 gtaaaaggaa ataccttttt tataaaaggt ggcacgaata caggaatata tgtatttgaa
     8701 gataacacag cacttatgat agacccaggg ttatgtggtt caagacctag gagagtaaat
     8761 aaagtattag atgaaaataa tatacaggtt agatatatta taaatactca tggtcatgat
     8821 gaccactatg gagcttgtaa tcaatttaaa gaatattata aagatgtgtg tataatgtca
     8881 tctgaatacg ataaattata tatagaaaat ccagaattgt tttcaaagta tattgttggg
     8941 ggaaagagca atgtatttat ggataatatc ttaaaaaata aaatgttgga tgatataaaa
     9001 atagataaat ttatagaagc tggaaaattt gaattaaaca atgaaatgtt tgatataatt
     9061 gaatttcagg gtcatacacc tggtagtata gctgttttga cgaaggataa tgtgattttt
     9121 gttggcgatt tattgatagg agatgaaatt ttatcaaaat acgatttctt gtttctatat
     9181 gatatacaag aacaaataaa ttcattagaa aaattaaaaa atatagattt tgagtactta
     9241 gttttagggc atggcaagca agttatatcg aaagaagatt cttataaatt aatagaaaaa
     9301 catttgaatg ctttaaaaaa atatttatat caaataagag agttgcttgt agaaccgaaa
     9361 tctttagaaa ttttattaaa aaacattata aataacaata atttaagcaa taattataaa
     9421 gagtatcatt tttttaaatc ttcgttagta tctgtcataa gttacttagt tgatttagaa
     9481 gaaatagggt atatattgga aaatggagaa ttgctttact atacaaaaac aaaataaatt
     9541 atgataaaat aaagaaggtc ataaaaaaca aataaagggt gagcaatatg gaatacgaaa
     9601 aatggaatga gatactagca ccttatgaac atgcagtaga ggaattaaaa ataaaattta
     9661 aaaatataag aaaagaatat ttagcaaaag gtgaatattc tcccatagag tttgtcacag
     9721 gtagaacaaa aaaaatatct tccataatat ctaagttaaa aaggataaat gcaaaagata
     9781 tagaaactga aattgatgat attgctggta taagaataat gtgccagttt gttgaggata
     9841 tatatgctat agttgatttg ataaaagtaa gaaatgatat gactataata ggagaaaaag
     9901 attatattac aaattacaaa gatagtggtt atagaagcta tcatgttata ataaaatacc
     9961 ctataaactc cattgcgggt tcaaaggaaa ttatatgtga aatacaaata agaactcttg
    10021 caatgaattt ctgggctaca atagaacatt cattaaaata taaatatgac cattacatac
    10081 ctgagactct tgctgaaagg cttagaagag catctgatgc tgcctttctt ttagaccaag
    10141 aaatgagtga aataagagag gacataatga aagctcaggc tatgtaccaa atgaagtcta
    10201 tagctattag agatactcta aatagaatac aagagttata tgacttgggt gatacacata
    10261 aagctatgca gtaccaaaga aaacttgata gaactgaaac agataaaaat ataactgaaa
    10321 ttttggaatt aaaacaagaa atagatatat tattagagca atataaggat actaaggtag
    10381 atgataaagt agttcagtaa aaactacttg tagaaaattt gctaaatatt aatggggctg
    10441 cctcttaatg gaaaataatt tctaaaaaga gacagcctat ttagtgtaat taagaaagga
    10501 atgatattat gagtttgtat gctataggtg atttacattt ttcaacatca gtcaataagc
    10561 caatgaatat ctttggaagt aattgggatg gtcatgaaaa gaaaattata gataattgga
    10621 aagaagttgt taaggaagaa gatatggtct tagtactagg agatacatct tggggaatta
    10681 atttatccga agctaaaaaa gatttagata taataagcaa acttccaggt cagaaaatac
    10741 ttataaaggg aaatcatgat tactggtgga caaccgttac aagtttaaat aagctatatg
    10801 aagacatgcg ttttattcag acaaattttt atgaatataa agattatgca atttgtggag
    10861 gtaggggctg gatatgtcct aatgatgtta aatttgatga gactgatgaa aaagtttata
    10921 aaagagaaga acatagactt agactatcat tagaatctgc tcgtaaaagt ggtcactcaa
    10981 aaataattgt gattactcat tatcctccta cgaatgataa attggaagaa tctttattta
    11041 caaagttatt tgaagaatat aatgttgaaa aggtgattta tggtcacttg catggtaaag
    11101 aatcttttaa aatgggattg aaggggattc gaaatggagt agaatataca ttagcatctt
    11161 gtgactatac agaatttaat ttaataaaag ttcacgatta aaaaacataa attggtaaat
    11221 actataagat acatgattaa aaataaatat ttgagggatt tcggttttga gaaaggagac
    11281 acgacttatg aggtggatat tagtttttat atttttatat cttattcctt tagtagtgat
    11341 attcagaaat tacaagaatt ttaagaggtc ttgtatctac agtagtattt atgtggtatt
    11401 agctacaaca ataatgataa gtaatattta tatgagtgga cttaataaaa taaaagagtc
    11461 tatgtattat cacaattata tttctgatga gacatatgat gaaaagtatg tatcaaattt
    11521 taaggaaaaa gaaagtactg atttaaacca ggataataaa aagaatgaag aaatatcaaa
    11581 taataaaaat ttaaacaaca aacaagatag aaatatacaa aataaagaaa gtaatgaaga
    11641 aggaagtaat gatataaaag aaaagaataa ttctgatagt aatgtttcag tgaataataa
    11701 atcagaaaaa caagaagata atacaaaaga aaataataaa tatacaagta aagaaaaaaa
    11761 tagtgaagat ataaaaaaaa tagatatgga aagtatagga atttttaaga aagaaattta
    11821 taatatagaa agagcagctt tagttccaat gagagaatgc ataccttaca ctaaggatat
    11881 agcaaaaaat ataactaaat tatctagtat aaaaaaagat gttacaaatg ccagaaacaa
    11941 gtgtaaagaa gttgtaaaag aatatgaaaa tatgcagatt ccagaacttt ctaaggagaa
    12001 gtatacagaa acattgagta atgctagaga tgacgtaaag aaagcatatg agcttagaga
    12061 aaaatctatg gaaagtgctt tgaaattaat aaatactaaa agccctaaat atatagggaa
    12121 gataacagaa tatcttgatt tatcagataa gcagatagaa agttttaaaa atagattgaa
    12181 cgatttaaaa gaagaaataa ataattcaga aacaaataat attaattaat aagatttaag
    12241 gatataagtt aaaagggaga ttatgatgaa taaacagagt ataggaaaac taaatatgtt
    12301 ttttatgggg attactcaaa gaaaccttga taatagggat ttttttattg agttagaggt
    12361 gatttttaaa tctggaagaa aagagtttaa aggaattgca atagaggaag ataataaata
    12421 taaatttaat tttaaaggaa aatcagattt atatacgttt aatgagttgc ttaagaatat
    12481 ttctaaagag gcagaaaatt atgatggatt agtatttaaa tatgttgagc gaggaactat
    12541 tgttgtaatt gaaggagaca ataagaaggt aaatgtaaaa tatttagata ataaggaaga
    12601 agtacctaaa atagatgaat ttacggcatc tcaaataaaa aacagagatt attatgtaaa
    12661 agtaggacaa gcaaatgcac ttttaaaaga aattggagta cttacaaaag atggtaagat
    12721 aaaaaatgat aaaataagaa aatacaatca gatagaccat tttgttgaat tgatagatag
    12781 tattttaaaa gaaataaagg ataaagactg tataactatc ttggattgtg cttgtggaaa
    12841 atcctactta agctttgtct taaattttta tataaaagaa gtattgaaga aaaactgtta
    12901 ttttatagga atagattatt cagatgtagt tatagaagca tcaaaaaata tggctaaaaa
    12961 cttgggttat aaaaatatgt catttataaa agaggatttg actaattata cacctaatag
    13021 ggatgttgac cttgtaataa gtctacatgc ttgtgatacg gctacagata tggcaatagg
    13081 tctaggaatt agagcaaaat ctgaagctat agtagtagta ccatgttgtc ataaggagct
    13141 attagggcaa tatagatatg aagctatgga accaatatta aaacatggtg tatttaaagc
    13201 tagatttgca gatttaataa ctgatggttt aagaacattg ttattggagg gcaatggata
    13261 tgatacttct gtagtagaat acatatctcc acttgataca ccaaaaaatt taatgataag
    13321 agcgataaaa actaaaacga ataatgacaa agcattaaaa gaatataaag aactgaaatc
    13381 acaatttgga gtggaaccaa ccttagaaaa acttatatat tagttaaaaa tgtaaaattt
    13441 acgaaaagct tgcttaaata tgcaagcttt ttggtattat ataggtatag tcatatccag
    13501 agttttgatt tataattaaa gctgtgctat aatatttgat taatcaaatc aataaatgtt
    13561 acatggaggt aaaaatgaac aaattgaata tatgtattga tatagatgga acaataacaa
    13621 gcccttatca ttttcttcca tacctaaatg atatctttaa taaaaatata actgaagcag
    13681 agtgtataac acataattgg gaagaattgt atggttcggg aataagagat gtgtatgcgg
    13741 agtttaataa taagtatata cactcatatg atgaagcaaa gattgtagag ggtgctacag
    13801 aggtaattag cacattatct aaaggacata atttatcttt tgtaacggct agacatgagt
    13861 gtttaactga tgtaactaaa aattggctat cgagacaagg attttcagat atagatgttt
    13921 acttattagg aagtgattat aaagttgaaa aggcaagaga actgagttgt gacatattta
    13981 tagaagataa tcctttaaac tcagtgcaac tagctgatga tggtgttaaa gtaatacttc
    14041 tggatactaa ctataataaa gatgttaaac atcaaaatat agttagagtt agtaattgga
    14101 tagatattga aaagattata aaacaaggta tttaaagatt tgtagattga aagggggagc
    14161 atatgataga tttaaaaatt gaaaatagaa aaggaaaaat ccatgtaaag agcagtgaaa
    14221 taaaagacat tttagaatta cgtccagact tcgaatatgt acaagatata tcaaatacta
    14281 taaatcaaga aaatatattg gtatttgatt gccagttgac aggaaattct tttgatatgg
    14341 atgatttaga tatagaagaa atattggaag agttaggtga agaaatagat gagtcttatt
    14401 tcagtgtttt atttgaagat gtaagagcgt atttaaaaga tgctactgat gagatagaag
    14461 cagacttaca ggataattac ttatttgata atttgagatg ttattttgat atatacaata
    14521 taaatcaaga atttacagat tttaagtttg tatttttagt ttcttttaaa gatataaaaa
    14581 tttcttcatt agcaaaccta gctaagattg tttctaagag acagcttata ggtgcatcta
    14641 agttttatag ttaaaatgaa agattattat aataaaagct agtaaccttg taaaaatata
    14701 ggttactagt tttttattta ttcattttca caaaatttca gaaaactatt tacattctaa
    14761 aaaaagtaat gtatattaaa cataatgtac attataatgg ataaaaagtt tctattaaat
    14821 tactaagttt atttaataat caaaataatt tatcttatat tagtatgtat tagggggtat
    14881 ttatgcaaag tttaaatgaa ataattgctg aaaatttaaa aaagataagg aaagaaaaac
    14941 atcttagttt agacaagatt gcacaactta gtggtgtaag taagagtatg ctatctcaaa
    15001 ttgaaaagtg tgaggtaaat cctactatat ctactttgaa gaaaataact aatgggctaa
    15061 aaatctcatt tacatcattg atggagaggc aggaaagtga catagaattg attcaaaaaa
    15121 gtgatataga ccattttatt gaagataatg gaaagtatat aagttatcca atatttccat
    15181 ttgactccaa aagaagattt gagatattta tgattgaaat agaagaaggt ggaaatttag
    15241 attcaaatgc tgaacttcca ggaacacaag agtttataac tgtttttagt ggcgaagtaa
    15301 ccattaaaat aaatggagaa gattacattg tatctagtgg aaattctata agatttaaag
    15361 ctgatgtatc acatatatat agaaactcag gcaaaggtat agctaaaatg agtatggtag
    15421 tatattatat ataaataatt taatggaatt agagtgatat ttagatgatt ttaggtatga
    15481 agatatatta tatttaagtt ataggagtgt gatttatgga tgaataataa aaaagcagtt
    15541 tttttctttt gcagtgattt aaagaaagac ccagtagcca gtaatgtgat aaaatgttgt
    15601 gaagaaataa tggatttaaa tcaaactgat attgttattg atgataattt tgtattagag
    15661 tttaaggata aaaacaataa cttatttcat tttgtaaaaa caaaagatgt aataagtcat
    15721 aattataaat attatcttcc aattttaaat agacatttta gagattatga ttttgcagga
    15781 gttgtaaatt ggcatgaggg agaaaatgct ccagaacata tcctaacagc tcatacaatt
    15841 ggagatgttc caacaggaga atttggaaat tcaaatccaa gatactttaa aaatctaatc
    15901 aatgctattg aggatataaa aaatgaaaat ctacttgatg aatttactac attaacagaa
    15961 gcaactcact ggtctggaac aacatatggt gaagaatcta aattaattac agaatattct
    16021 gtacctatgt tggatattga gataggaagt agtagtgata gttttaataa tagtatagca
    16081 atacaggtat tggcaaaatc attaattaga gtatttgatt gtgatgaacc tttgaagact
    16141 ttgttatgtg ttggaggggt acattttgag aaatctttct cagatattat aaaaaataaa
    16201 gaatataaca tatcaattgg acatgtattg ccaaatcaat ggattgtaag tggaatgtat
    16261 gatgatgaat ctggatttga gaaactagaa aagtgtataa atagtattga aggaggaatt
    16321 gattgtatag tttttcatga taaattaaaa ggtacctata aagagcaatg tcgtaaacta
    16381 ggtgaaaaac ttaatgtacc tgtatttaaa cataaaatat taaaaaatcc aaaagactta
    16441 cctatatggt agttttatac agttaatata acaataagtc ggattaattt ttaagcgagg
    16501 tcaaaaatga tattatctta ttttgcatta ttaattagag tagtgctatt agcttttgaa
    16561 agagtagttg taagattatt aggtgatgaa gaaggagata tttataaaaa tatagcttca
    16621 tcatttctat ttttctttat agggggagta tgtttacttc catttagcat aatggataga
    16681 gttagtgatt ggtcgttttt aataccatgt tatataagta gtttagtcta ttcaattggt
    16741 tcagtagcgt atgtaacgtc tttagcaact ggggaagttt cacttgttac tccaataaat
    16801 agtttaaatt cattgttttt actgctttta tcagttatat ttttaggtga aggtttaagt
    16861 ttagcaaaag ttgcaggaat cataattatg attggtggag tgtttatatt aaaaaaagta
    16921 agctcttttt taaagaatgt ctctgtaatt tttaacaatt taccatgtag attaatgttt
    16981 ttatacatat ttttgcagtc agtaggaaga gtattggata aggctttttt tgtacaagta
    17041 tctcctatat tatattcaac tatactgtat tttttcgtag gtttaaattt atttatcttt
    17101 ttagcattta aaaagaaaca aaaaataatt tgtgagattt ttagtaataa aaaggggctt
    17161 tcaattttaa gtggtgctat taatggatat tcttatttag cattattaat tgctttaaat
    17221 aatctagaac ttagtatagc agagccattt tctcaagtat ctatgataat aactttaata
    17281 cttgctcatt ttatattcaa agaaaatata aaagaaaaaa taccaggttc aattttgata
    17341 ctaattggtg ggtggctact gttactttaa ttgatataaa aaatgaatta taaaggtgct
    17401 attagttagt atcagaaaat ttaaaaaagt attgacaatt cttttaggca aatgttaata
    17461 taataataca aaatagtata aatagaagac atgttactgg taatgcaggc aggatcgaat
    17521 atattgcttt gatttttcaa ggtgtttata taggttctgc cttttttgca tcttgaatgg
    17581 ccattcataa aaaattatgg agaaggagat tacaagatga attataaaaa aactgccatt
    17641 gacattattg aacaagttgg tggttcaaaa aatattttag ctttagaaca ctgttcaact
    17701 agactacgct ttaagttgat tgatagaagt aaagtcaatc aggatgcttt aaaaaaagta
    17761 caaggtgtta tgagtatagt taatggggca caatttcaag ttgtcattgg aaatagtgtt
    17821 gttgatgtgt atgatgaaat tttaaaagtt tgccctttag atacaaatga tagtactgta
    17881 aaaactgaag aaaaaataaa cttaggaaca agatttatag aatttattat taatattttt
    17941 caaccactga tttttgctat tgcaggagct ggtattttaa aatcactgtt gatgttatta
    18001 gcaatgttta atattttaaa atcagattct actatatata cattattagt tgctatttca
    18061 gatgcaacat tctatttcct acctcttatg gtagctgtaa ctactgccaa tgtattgaaa
    18121 tgtaatcgtt tagtagctat tgccgctgta ggatacttat tgcttccagc aacaacaact
    18181 gctttaagtg aaggtgtcga actatttgga tttacaattc caaacattgc ctataatgca
    18241 caggttttcc cggctatctt atgtgtgtct ttcttggcaa caatggagaa aatttttaac
    18301 aagtattcac caaaaccaat tcgaactttc tttgttccta tgatgtcttt ggcaattact
    18361 gttccaatta ctctaactat tttaggtcct ttaggatata acgttggtac aatttttaca
    18421 accattattt tattcttata taacaaaatg ggattcttag ttgtaggatt acttgctgct
    18481 tttcttccat ttatggttgc aacaggaatg cacaaagcac taatacctta ttcaattaat
    18541 acaattggaa agttgggtta tgaagcttta tatatgacat cttcattagc ccacaatatt
    18601 tctgaaagtg gtgcttgttt tgcagtagcc ttgcgaacaa aagatgaaac attaaaacaa
    18661 acagcattat ctgcaggaat ttctgccttg atgggaatta cagagccagc tttatatggt
    18721 attactttac aacataaaag agcaatgtta ggtgttgtat tctcaagtgc aatttctggt
    18781 acatttttag gattatttgc agtaaaagga tttgtaattg ttggaccagg gcttgccagt
    18841 atgagtatgt ttattgaccc aaacaatgga aacaatttga tttttgcaag tattggtttt
    18901 gttattgcaa tattaggctc gtttattatt acactgatta tttggaagga agatacaaat
    18961 acagtagagt catcaattgg agatgttgtt gaagaagagc tagaagaaga aaaagaagta
    19021 aatatcttag taactccagt agaaggaaaa gtaatagatt taagtaaggt taatgatgaa
    19081 ctatttgcaa gtaagacttt gggagatgga gttgcaatta taccgaccaa tggaaattta
    19141 tacgcacctt gtgattcaga agttgtgatg ttatttgaaa caaaacatgc aattggttta
    19201 agaacaaaaa atggggctga gattttgatt catattggaa taaatactgt aagtatgaat
    19261 ggagatggat ttaaaacatt tgttaagaca ggcgataatg taaaagaagg agatttatta
    19321 attcagtttg atttagacaa aatctcacat gctaatttag attcaactgt tatgattgta
    19381 aacaataatg gagcagatta tgcttataaa gtgttaaacc agtcttatgg caatgtaaaa
    19441 aaaggaagta tcttgtttga tgtaaaggga ggaatataaa tatgagaaag tttccagaag
    19501 gatttctttg gggaggagct acagctgcta atcaatttga aggtggttgg aatttaggtg
    19561 gtaaagggtg gtctgtatca gatgtagcaa aggcacactt tgatgcagat gtgaaagatt
    19621 ataaatctaa taatgaaatc acaacaaaag atatagaaga aggattagca catcctgaag
    19681 atgaagtaaa ttatccaaaa cgtcatggta gtgattttta tcatcactat aaagaagata
    19741 ttgctctaat ggcagaaatg ggatttaaga catatcgaat gagtattgct tggtctcgta
    19801 tttttccaaa tggagatgat aaagagccaa atgaagaagg tttacagttt tatgatgatg
    19861 tatttgatga gttgataagt tatggaattg aaccacttgt tactatgtca cattatgaac
    19921 caccattaaa tatcgtttta aactatgatg gatggtattc acgacaagtt atcaatatgt
    19981 ttgttaggta tgtagaaact atctgtgaaa gatataaaaa caaagtgaaa tattggctta
    20041 catttaatga agttgattct atgattcgtc atccgtacac tactggtggt ttagttcgag
    20101 accgttttaa ggataaaaac tttgaggaag ttatttttca agctatgcat catcaatttg
    20161 tagctagtgc ccttgcaaca aaaatttgtc atgaaattat tccaaattca aaagtagggt
    20221 gtatgttaac aaaattaacg tattatccat acacatgtag accagaagat gttttggcaa
    20281 ctcaacgaaa aatgagaagt atttatgcat atagtgatac gcaggttttt ggtgagtatc
    20341 cagtatattt actgtcgtat tttaaaaata ataacattca aatagtaaaa gaagaacatg
    20401 atgatgaaat tatgaaaaag tatccagtag attttatttc attctcttac tatatgtctt
    20461 cttgtgaggc agctgataca actggattag atattacacc tgggaatacg ttattagctg
    20521 taaaaaatcc ttatttagaa atgagtgaat ggggttggca aattgattca ataggtctac
    20581 gtatatcttt gattgaatta tatgatagat acagaaagcc tttatttata gttgaaaatg
    20641 gattgggagc caaagatatt ttaactgaag ataaaaaagt tcatgaccaa tatagaatta
    20701 attatttaaa agaacacttt aaatgtatgt tagatgcgat tattgaagat ggtgttgaac
    20761 tttggggata tacttcatgg ggttgtattg atttggtcag tgaatcaacg aaacaaatgt
    20821 caaaacgtta tggatatatt tatgtggatg ctgatgatta tggaaagggg acatataatc
    20881 gatataagaa agatagtttt tattggtata aaaaggtaat tgaaagtaat agtatagatt
    20941 ttaaatgacc aatagaaggt gagcaaataa aatgaactac ataataaaga aagttttgaa
    21001 ctcgagcgtt gttttagttc atgacacaaa ggataatgaa tttattttgc tagggaaagg
    21061 aattggatat ggtaaaaaaa caggagaata tatttgtggt tccaatgata atcaaatgtt
    21121 tgtccctgtt gaaaatacaa aatcaaaaca atttttagaa ttaatggatg atattcctgt
    21181 cgacatttta aagataacac aggaaataat agtagaggca gaaaagttat tgaactcatc
    21241 ttttaataaa aacttatact taatattagc agaccatttt aactttgcaa ttgaaaggat
    21301 gcgtaaagga ataaaaatta caaatcgagt attttgggaa ataaaaaatt attatccaaa
    21361 tgagtttaag gttggaatgg ttgcaattta tatggtagag gagagattgg gcattcaatt
    21421 accagaggaa gaagcagcta acattgcttt ccattttgca aatgctatgg cttcagatgg
    21481 aaattcatat gatacgatta agtatgccaa agtaattgga gaaataatta atatttttgt
    21541 tttttctttg aatagaacct tagataaaaa gagtatgcat tatatgagat ttataacaca
    21601 tataaaattt tttgtggaaa gatttttttc agatagtatg ttaagcagtg gtgatgattt
    21661 attatttaat caaatgaaaa ggtcaaatcc aaaagaaatg ttaattgcat taaaagttag
    21721 agatttttta gaaaagaaat atggaaaaaa gttaacaaat gaggaaatag ctttcttggt
    21781 tgtccatatc gcacgagtta agcaatagag tgaattacta atattatctt atacgtctac
    21841 atggtagaaa attgaaagaa ggtaaagtat ataaagaaac tgagacatat tattttgttg
    21901 ttcattatgt ttattttatg agtgtatcct gttaaaaatt taagttaata tttataatta
    21961 aaatatacaa atagttaaaa taagtttatg tggttatgaa tttattttaa ctattttttt
    22021 gtttaatg
//
LOCUS       DAJMZY010000068        21909 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.068, whole genome shotgun sequence.
ACCESSION   DAJMZY010000068 DAJMZY010000000
VERSION     DAJMZY010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 21909)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21909)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21909
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.068"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            complement(240..704)
                     /locus_tag="OE968_002440"
     CDS             complement(240..704)
                     /locus_tag="OE968_002440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4624 domain-containing lipoprotein"
                     /protein_id="HCP7219716.1"
                     /translation="MKKLVIILISIISMVSLTACKKSNESKYNNLNNKESGQTTIEMD
                     LDKNYDTSDPFVNARLFCVSNDIDVLDTEISFKMDGDSGIVEIKDNKTDETLWSNTWH
                     GSVDNDTFTISLSNIQKEKEYAICFTGIKINHAVVKVTFESNLVKEKEKPSK"
     gene            complement(1028..1636)
                     /locus_tag="OE968_002441"
     CDS             complement(1028..1636)
                     /locus_tag="OE968_002441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HCP7219717.1"
                     /translation="MKKTIIKNVNPMIENKFIGLFEIEYKNKLDEDKVWMVASRKSSE
                     QLKNIYLKNEEDSVDAVVIVGLHKSSKKLILIRQFRVPINGYIYELPAGLVDEGESID
                     ISVERELREETGLTLLEIKKNKSIDKVYLSPGMSDESVAFVYCICDGDITDEFLEPDE
                     EIEALLISQEDAKEILQSNHKIDTKAFLILQMFVSLGAKLFE"
     gene            complement(1718..2419)
                     /locus_tag="OE968_002442"
     CDS             complement(1718..2419)
                     /locus_tag="OE968_002442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219718.1"
                     /translation="MKFIVEKEVFDKLENVCFGVVVAKGIDNTKEIERISNLLDISID
                     RVEDYFKDKKVKESEEIIPYREAFRSLGMNPNKFMSSIEAMTTRVAKNKKLPHINPIV
                     DLGNSISLKYLLPMGAHDMDFRNDDVYVRFSKKGDKFVPFGETDVELMEEGELIYSVG
                     DMVKTRRWIWRQGEEGKITNSSKNIFFPIDGFTDANLDKVMSAREELAKLLKEIFNCE
                     IKVGFVDKDNPEMEI"
     gene            2646..2912
                     /locus_tag="OE968_002443"
     CDS             2646..2912
                     /locus_tag="OE968_002443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HCP7219719.1"
                     /translation="MKNFILIYFIVINSIAFFSMYIDKKRAIRNEWRIKEATLMSIAV
                     IGGSIGSIIGMYSFRHKTKHIKFTFGIPFILFLQFLLVYFYILK"
     gene            complement(3015..3434)
                     /locus_tag="OE968_002444"
     CDS             complement(3015..3434)
                     /locus_tag="OE968_002444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjdF family protein"
                     /protein_id="HCP7219720.1"
                     /translation="MDKISGKLTVLFEEPFWVGIFERQDGKKYEACRVVFGAEPKEVE
                     VYEFILERFFSLDFGSIKLEKNVTKDNIGYKRMQRKVKKEQEKETIGTKAQNALKLQY
                     EERKQDRKNLAKNRKEEEKERLFNLKQEKRKAKHKGH"
     gene            complement(3701..4483)
                     /locus_tag="OE968_002445"
     CDS             complement(3701..4483)
                     /locus_tag="OE968_002445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HCP7219721.1"
                     /translation="MEYYIVDSFATKLFKGNPAGVCVLDRRIPLELMQKIAEENNLPE
                     TAFVVKGKGNYELRWFTPKAEIDLCGHATLAAAYVISNFIDVNVKRIDFFTQSGKLEV
                     TRNGNLYEMIFPEIMPIEIELSPQQANLIGCVPSAVYSSRDLILLLNSEQEVINYKPN
                     YAQLRKLTDWLGIIITAQGSNTDFVSRYFCPELDSEDPVTGSSHCNLIPYWSEKLGKH
                     KMVAAQLSNRGGIIQCEVLKDNTVKISGEAVLFMQGTIKIDI"
     gene            complement(4548..5309)
                     /locus_tag="OE968_002446"
     CDS             complement(4548..5309)
                     /locus_tag="OE968_002446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896901.1"
                     /note="N-terminal region resembles flavodoxins. C-terminal
                     ferrodoxin region binds two 4Fe-4S clusters; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EFR1 family ferrodoxin"
                     /protein_id="HCP7219722.1"
                     /translation="MIGIYFSGTGNSRYCVEKFLQEYDITANSYSIEDNELLQHINNH
                     ENIIFSYPVQYSNVPKILKDFIINHSTLWNGKRVFIIATMALFSGDGSGVLSRILKKY
                     GAITVGGLHVKMPDSIGDEKVLKHSLEYNRKLVIKAEKKVTKAAKKLKHGSPPKEGLG
                     FLSHIVGLFGQRLYFINKTNMYTDKLKINTEECIVCGKCVNLCPMKNLVIKNCMIVAN
                     GQCTMCYRCVNNCAKKAITLLGKKVVEQSNIKKYM"
     gene            complement(6357..7169)
                     /locus_tag="OE968_002447"
     CDS             complement(6357..7169)
                     /locus_tag="OE968_002447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HCP7219723.1"
                     /translation="MYLERPELYKQSEINFWDDEYISKQLLKAHLDTNFEGASRNFNF
                     IEDSVNWIVTVANPANYPKLLDLGCGPGLYAEKFAQKGYKVTGIDFSKRSINYAQNRN
                     KETNLNINYLFQSYLNMNYNEEFDLATLIYCDYGALSTENRRLLMEKIYDSLKPGGKL
                     ILDVFTINKYNNFEEIKYWEINEDGGFWSNEKYMCLQDNCKYNDYNTLEQTLVITEKD
                     ENVFYVWNHYFSKESFLLEVENIGFKSVEFFSNVKGEAYSDDSMTMGLVLQK"
     gene            complement(7539..8441)
                     /locus_tag="OE968_002448"
     CDS             complement(7539..8441)
                     /locus_tag="OE968_002448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HCP7219724.1"
                     /translation="MYNKIKYIPINCEIACNKLKRSMPYKWDLNIYRGCEHGCKYCYA
                     IYSHKYINSNNYFEEIYVKTNIVEKLERQLKSSKWKKEVINIGGVTDSYQPIEADYKI
                     MPEILNLLIKYKTPAIISTKSDLILRDYDLIDKLSRITYINVASTITTVNEDTQRLIE
                     PNGVDSMRRFKMLKEFRKTNASVGLHIMPIIPYITDDFDNINSLFRHAKECNVHYVLP
                     GTLYLRGITRGVFFDFVKKEFPELFDKLSILYSAGSLNREYKNQLYKMVNELRYKYSL
                     SSSYSKIMKEKLKNSGDVQISFFD"
     gene            complement(8491..8952)
                     /locus_tag="OE968_002449"
     CDS             complement(8491..8952)
                     /locus_tag="OE968_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine dimer DNA glycosylase/endonuclease V"
                     /protein_id="HCP7219725.1"
                     /translation="MRLWHKDLIDVLPKNQLVSQWRELLAIKGSIDKKGTPNHLLVNK
                     VLNYSIDEFKFYTKIVHDEMLKRNYKPNELKYTSILKWKNRNFANDISNEHSLNLENL
                     YDDWHNKMYLKQCLYNLEEKATCGGIPINEWNILLCKYSKDYELWSGNIMF"
     gene            complement(9004..9459)
                     /gene="def"
                     /locus_tag="OE968_002450"
     CDS             complement(9004..9459)
                     /gene="def"
                     /locus_tag="OE968_002450"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HCP7219726.1"
                     /translation="MAIRKIRTFDDEILRKKSKYVENVDNKIREILNDMAETMYNTPN
                     GGGLAACQVGVLKRLVVIDLGEGLIKLVNPEIIEQEGEQIVVEGCLSFPEVWGKLKRP
                     KKVTVQALNEYGEKIEIKGSGFMAKCLCHEIDHLNGIVFTDKIIEHVKL"
     gene            complement(9431..9694)
                     /locus_tag="OE968_002451"
     CDS             complement(9431..9694)
                     /locus_tag="OE968_002451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCP7219727.1"
                     /translation="MKNKIKILREKLGLTQEQLGRLVGTSRQAINAIETGKNEPSIWL
                     AYDISRIFNEPIESVFLFEESERKSRAQISRGEYYGYKKDKNI"
     gene            complement(9791..10507)
                     /locus_tag="OE968_002452"
     CDS             complement(9791..10507)
                     /locus_tag="OE968_002452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCP7219728.1"
                     /translation="MIKIINAFKQEFEQIKRDAMLFIVCVSPILCGVFIKFGIPLIQN
                     ISLNKFYYQLNLEPYFLMFDLLLAFITPFMFFFASTMVILGEIDDSISRYLIVTPLGK
                     TGYLISRFGIPGILAFIITMILLIFFSLTKISLLLNLSISLLVLLQGVIISILVISLS
                     SNKLEGMVITKFSGVFMMGILAPFFILNKAQYILFFLPTFWISKAFKEDNYVYMFISI
                     VISLIWILLLFKKFSKKIVK"
     gene            complement(10504..11187)
                     /locus_tag="OE968_002453"
     CDS             complement(10504..11187)
                     /locus_tag="OE968_002453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCP7219729.1"
                     /translation="MRLKNLILGDIKFQFKYGFYFLYLFLSIIYICIINVFPTFMREK
                     IAIIMIYSDPAAMGLFFMGAIVLLEKSQRVLNSLAVSPVKVSEYILSKVISLGVISSI
                     VAMFIAITLNLDNIIISTIGTFFSSIIFSLLGLIIASKASSLNQFIVLSIPIEIICFI
                     PPILNVLLDTKSYANLYPFNICISLISGDKNFIMINILILISIIIIIYFITYYFICSS
                     WKKVGGVKL"
     gene            complement(11184..12029)
                     /locus_tag="OE968_002454"
     CDS             complement(11184..12029)
                     /locus_tag="OE968_002454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCP7219730.1"
                     /translation="MIKVDDLSFSYTDRDFLQNINFEVGKGEILGFLGPSGAGKSTLQ
                     KILIGMITNYGGSVIVNGVESKRHSNKFYENIGVDFEFPSLYEKLTAIENLKYFGSLY
                     SKKLLSIDELLKSVGLENESNKRVSEYSKGMKSRLNFIKALLHNPDILFLDEPTSGLD
                     PSNSKVMKDIILSEKSKGKTIILTTHNMLDATELCDRVAFIVNGKISALDTPHNLIMS
                     KGAIKVRYTYFDNGEKTSECFLNNTANDKNLNMLIEKNKLLSIHSSEPTLNDIFIEIT
                     GRNLQ"
     gene            complement(12143..12733)
                     /locus_tag="OE968_002455"
     CDS             complement(12143..12733)
                     /locus_tag="OE968_002455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCP7219731.1"
                     /translation="MPKSYSDKEREYIIKRLKEEARLCMEQYGIRKTTVDELVKRVKI
                     PKGTFYLFFQSKELLFFEVLRDIHDSIQKEILYEINRVDESITCEQLTDIFMKFYRMV
                     DSTSILNLMINGEFEILVRKLPDSIIEEYFRHDDFEIGEIISCIPNAKNKDIESFSGA
                     FRAVFLTMLYKREVGSNCFEDALRLMINGLVIQLME"
     gene            13022..13255
                     /locus_tag="OE968_002456"
     CDS             13022..13255
                     /locus_tag="OE968_002456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HCP7219732.1"
                     /translation="MATTTKNRFYDYVQENLNKYVEVHSYFSSCPLYGEIIEADSLSI
                     TLCSRYIDESNPTLNETYTLYLPLSSIISIRTL"
     gene            complement(13486..15873)
                     /locus_tag="OE968_002457"
     CDS             complement(13486..15873)
                     /locus_tag="OE968_002457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding cysteine protease Cwp13"
                     /protein_id="HCP7219733.1"
                     /translation="MKKFTSKKVTRFVALFLISILVMSTIPVSADNSNTLNQIKKAEY
                     SETYKQYLNDAKNGCTEKYNGIIPNPYQLEGTQIQSKGRTAPTSYDPRKLGLMTSIKN
                     QEDLGICWDFAAMATLESFLKLNNYGDYDLSEEHLRWWASDGEYGWSVNDMNGALNYE
                     AMGYLTSWSGPKLEKDIPYNGRVSKAQGAKKPTNMNTAPTVFNVTDAVCVSNDINSTK
                     NAILQYGAVTSGYYEDIKYQSDDQNSYYCPTKSFNTNHAISIVGWDDNYSKDNFNANI
                     RPSKNGAWLIKNSWGDYNSEGGYFWISYEDKTLMSDIDNFSIKGGKKPNDDEKMYQHD
                     YASIVPLISKKITAANVFDFNRGDETLKSVMFLTESIGAKYEVYYAPVVNGIPQENNM
                     KKLKEGTAQYSGYITVPIDSFDIPEGKGAIVVSIEGKNGESTIGSESNVPGYDTFKAK
                     ANLGESYIIDNTGKFFDINRDSNFYPCNFTIKAVTEKSSGESIPNESLIGSDRYETAI
                     KVSQNGFNSSENVVLVNGSSIVDALAATPFTSAINSPILLTQKEALNSKTKAEIQRLG
                     AKKVYLIGGENSISKEIEQQLKSLNISIERISGSDRYKTSLLLAQKLNGIKNVSQIAV
                     VNGVKGLADAISVGAAAAENNIPIILANEKSELQGADEFLNSLNIEKSYIIGGTASLS
                     NNLESKLKNPTRLSGSSRDETNSKIIDNFYKKDTLKNAFVVKNGIKNQNDLIDGLAVG
                     PLGAKTGSPVILVGDKLADSQKEVLKNKTLEKVTQVGGGANKNAFKELVKLKSAK"
     gene            complement(16065..16820)
                     /locus_tag="OE968_002458"
     CDS             complement(16065..16820)
                     /locus_tag="OE968_002458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyglutaryl-CoA dehydratase"
                     /protein_id="HCP7219734.1"
                     /translation="MFSIGVDSGSVATKGVLFDGEKIIKKIIIPTGWSPKSTSKQVYE
                     LLSSEIDKKDIKKVVGTGYGRGVMDFADKKVTEITCHTRGIYFLNKNIRTILDVGGQD
                     SKVINLDRDGNVFNFIMNDKCAAGTGRFLEITSNLLGSDIESIDTLAKGYEPVNISSM
                     CTVFAESEIVSLLAQNISTGEVAAGILKSIANKSTSMLARGEVIDEVAFTGGLAKSKE
                     LVKMIEEILGKKIFIAEDTQIIGALGAAVIGFR"
     gene            complement(16845..17996)
                     /locus_tag="OE968_002459"
     CDS             complement(16845..17996)
                     /locus_tag="OE968_002459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyacyl-CoA dehydratase"
                     /protein_id="HCP7219735.1"
                     /translation="MTNLPKQFDSFNEARQKGFINAKELKESGKKMVGVFCTFTPVEI
                     PMAAGATVVGVCGVSEEPIPDAERVLPRNLCPLIKSSYGHAITDTCPYFYFSDLLIGE
                     TTCDGKKKMYEELAKVKPTYVMHLPNTSKGEFAYKLWKDEMIRLKEEVEKSLGVTITE
                     EDIRTAIKDKNEERELLKEFYALGKLQPSALTGLELHNVLYQAGFKFDRAELKHSLRK
                     VIDDMKERYEKGECPVQKDKPRILITGSPIGGISEKIVKTLEDAGASVVAYELCGAIR
                     SNDLLVDEEIEDVYDALTQKYINIGCSCMMNNDNRIELLDRIIDEYNVDAVIDVVLQA
                     CHTFNIESYRIREFVTKEKNKPFMSLETDYSKSDTEQLRTRFEAFVEML"
     gene            complement(18212..18952)
                     /locus_tag="OE968_002460"
     CDS             complement(18212..18952)
                     /locus_tag="OE968_002460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EcsC family protein"
                     /protein_id="HCP7219736.1"
                     /translation="MKDYEDVVYIKLVKKELEEWKKNILKKPSIFDKASKGIQNKFNG
                     VLPDKYHEIITSSIKVMTKTVLFGYKYATKPPLRNMSLEEREKLVLEKAKTYKTTAMI
                     EGAGTGAGGILLGLSDFPLLLGIKVKFLYDVASIYGYDVKDYRERIYILNILQLAFSS
                     QQHINKTFKLMNNWDEYVNSLPEDINDFDWRTFQQEYRDYLDLAKFLQLMPGIGAFVG
                     FYVNGKLIDKLCETAVSAYRLRIRELKL"
     gene            complement(19024..20013)
                     /locus_tag="OE968_002461"
     CDS             complement(19024..20013)
                     /locus_tag="OE968_002461"
                     /EC_number="3.5.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HCP7219737.1"
                     /translation="MFENLPKIDLHCHLDGSVRVETMLDIAIKEKIDLPSNNMDEIKK
                     LAKVSFNCTSLDEYLEKFDLPLKVMQSKENLKRITFELLEDASRENVKYIEIRFAPLL
                     HTQKGMSVKNIIEGIIEGIREAESIYDIKGNLILGCMRTMTSKEALLVIEEGKSFVNK
                     GVVAVDLCGPEKEGFCKEYKDVFKLAREYGYKVTIHAGEAASGENVLDAINILKADRI
                     GHGVKIKDHKKAYNLVKDKKILLELCPTSNVQTKTVDSYEAHPFYTFYKDNLHVSINT
                     DNRTVSDINLSSELNVIFDTFKLGLEDYKIIYRNAVEASFADKETKEYLNSLI"
     gene            20273..21526
                     /locus_tag="OE968_002462"
     CDS             20273..21526
                     /locus_tag="OE968_002462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:glutamate symporter"
                     /protein_id="HCP7219738.1"
                     /translation="MITLSFDIVQTLTLSIFFFLIGNLLKNKVNFLNNFCIPAPVIGG
                     LLFCFLNLFFKYFNIADISISGNLMPNFITFFFTTIGLEISINLIKKGGSVLFRYWIL
                     CGVLAFCQNILAITISKIIKLEPLLGLMCGNVSMEGGHGYSAAFGLTIENLGIEGAVG
                     VGLSAATIGLIMGGILGCPVAKFLINKYKLKPSSNIDLSIPRYNRNLKRFGSKFFRNK
                     NRIKNNNFSETITPSVFLEQVLLIFICINTGEIISRCFYITFNILLPSVVTCMFSAVI
                     FRNLNDKINILELNFKLIDFLKELSLGIFLTLSLMNIDLFELSTLLPPILLIVTFQVI
                     FIILFSIFICFRVLGKDFDSAIIISGLIGHGIGATPNALANMSSLTQKYGDSPKAFLV
                     VPLVSGFLLDAISIPCILFFINILT"
     gene            21623..21847
                     /locus_tag="OE968_002463"
     CDS             21623..21847
                     /locus_tag="OE968_002463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HCP7219739.1"
                     /translation="MTVYNLKLGQKGIIDNIAGNEKLMKRLLALGLIDGTEVEVKKIA
                     PLNDPIVIRFRGFDLAIRKSDAKNINLKNN"
BASE COUNT         7279 a         3631 c         2196 g         8803 t
ORIGIN      
        1 aattagctta ttgttaacta aattatggaa atatacttaa ttgaaaactt aaatttattt
       61 ccttgtatta tcaagatttc atgcttacca tttccaatat catgctcacc aacttttgat
      121 gtgcataaac tatttcaagt aaaaatgcac aacctatcct ttttgataag aaaaagcagt
      181 caatcataaa tatcaactgc ttttatgtac tgaatatcaa gttatagaaa agctggaatt
      241 tattttgagg gtttttcttt ctccttaact aaattgcttt caaaagtaac ctttacaact
      301 gcatgattta ttttaattcc agtaaagcat atagcatact ctttctcttt ttgtatatta
      361 gaaagagaaa ttgtgaatgt atcattatca acgcttccat gccatgtatt actccataaa
      421 gtttcatctg ttttattgtc ctttatttcc acaataccac tatctccatc cattttaaaa
      481 gaaatctctg tgtctaaaac atctatatca ttagacacac aaaacaaacg tgcattaaca
      541 aatgggtctg aagtatcata atttttatct aagtccattt caatggttgt ttgtccggat
      601 tctttgttgt ttaaattatt atatttactt tcattgcttt ttttacaagc tgtcaagcta
      661 accatactaa tgatactaat taaaataata actaattttt tcatagaatt tatctccctt
      721 acaatttcta atttttaacc ctacaaacta tagtattaaa ctaagctact attttacatc
      781 aaatttttca atcattcagc ctttacattt tctcatttta attgcaaata tgttaaataa
      841 ttttggaatt ttaattattg tagtatctta aattggttta taacatatta tgaaaattta
      901 agagtcaaat cacttattta aaaatacaca aaattatact ttattgtata aaaaaagaga
      961 ttataattta cacaagtaaa ataaacttta ttattttact cttctatata acctcttttc
     1021 tatatatcta ttcaaataat ttagctccta aactcacaaa catttgtaaa atcaaaaatg
     1081 cttttgtgtc tatcttatga ttactttgta aaatctcttt tgcatcttct tgcgaaatta
     1141 aaagcgcttc aatctcttca tctggttcta aaaattcatc tgttatatca ccatcacata
     1201 tacaataaac aaaggcaaca gattcatcac tcattccagg agataaataa actttatcaa
     1261 tacttttatt ttttttaatt tctaaaagag taagtcctgt ttcttctcta agttctcttt
     1321 caacggaaat atctatagac tctccttcat caacaagacc tgctggtaac tcgtatatat
     1381 atccattaat aggtactcta aattgtctta ttaaaattaa ttttttacta cttttatgaa
     1441 gcccaactat tacaactgca tctacactat cttcttcatt cttcaaataa atatttttta
     1501 attgctcact actttttctt gatgctacca tccaaacctt atcttcatct aatttgtttt
     1561 tatactctat ttcaaaaagt cctataaact tattttcaat cattggattt acattcttta
     1621 ttatagtttt tttcaaattt actacgacct ttctttttta ataccttttt aacatcatta
     1681 agtaaatata atatcttaac aagtattcaa caacttatta tatttccatt tcaggattat
     1741 ctttatctac aaaacctact ttaatttcac aattaaatat ttcctttaac aattttgcta
     1801 attcttctct tgcactcatt accttatcta aattagcatc agtaaaacca tctataggaa
     1861 aaaatatatt ttttgagcta ttagtaattt ttccttcttc tccttgtctc catatccatc
     1921 ttctagtttt taccatgtct ccaactgaat aaattaattc tccttcttcc attaattcaa
     1981 catcagtttc tccaaatggt acaaatttat cccctttttt agaaaatcta acatatacat
     2041 catcatttct aaaatccata tcatgagcac ccattggaag taaatatttt aaagaaatag
     2101 agtttcctaa atctacaata ggatttatat gaggaagttt cttattctta gcaacccttg
     2161 ttgtcattgc ttctatcgaa ctcataaatt tatttgggtt catgcctaga cttctaaatg
     2221 cctctctata tggtataatt tcttctgatt cctttacttt tttatctttg aagtaatctt
     2281 ctactctatc tatacttata tctaaaaggt tgcttattct ttctatttct ttagtattat
     2341 ctattccttt tgcaactact acaccaaagc atacattttc taatttatca aaaacttctt
     2401 tttctactat aaatttcatt ttgctttatc ctcctgttat tttacattat tttctaaata
     2461 gattttatca ctttgtgtct tataaatata ccccctattt gctaattgtt taattttttt
     2521 aaattttcca attaatatta tatttgttct tatcaaatat tttatatgta ctaattacaa
     2581 atttaacttt ccaaaacaaa tatcttgttt tataatgtat aatatatttt tatggaggca
     2641 agactgtgaa aaattttatt ctaatatatt ttatagtgat taattctatt gctttctttt
     2701 caatgtacat agataagaaa agagcaatta gaaacgaatg gagaataaaa gaagctactc
     2761 ttatgtctat agcagtaatt ggaggtagta taggttctat aattggaatg tattctttta
     2821 gacataaaac taaacacatt aaatttacat ttggtatacc atttatacta tttttacaat
     2881 ttttattagt atatttttat attttaaagt aattgaaata taaaacctta ttcttttcaa
     2941 taaattaagg tgtataaaat taaaaatttt atacaccttt ttctagcaat tattaaaaag
     3001 atatttaatt aaaattaatg acccttatgt ttagcttttc tcttttcttg tttcaaatta
     3061 aatagtcttt ctttttcttc ttcttttcta tttttagcta ggttttttct atcctgtttt
     3121 ctttcttcat attgaagctt aagagcattt tgagccttag tccctatagt ttctttttct
     3181 tgttcctttt ttacttttct ctgcattctt ttgtatccaa tgttgtcttt ggtcacattt
     3241 ttttctaatt taatgctacc aaaatctaat gagaaaaatc tttcaagtat aaattcatac
     3301 acttctactt ctttaggttc tgctccaaaa actaccctac atgcttcata ttttttacca
     3361 tcttgtcttt caaatatacc tacccaaaat ggttcttcaa ataagactgt taattttcca
     3421 ctaattttgt ccattgctag ttcctcctta aattactttc taaagaacgg acaaccaagg
     3481 aggcaggtta ctgacagcta ttgctgcgtc tggactacca accagactgt gtttttatct
     3541 ttatagatta aatattatct tttttaatca tgcttgtcaa tcttagtatc aacatctatc
     3601 atattgattt aagtgaaatc aagtttttta actctacttt attattgtta acactaagaa
     3661 aattaattat ttttcataat aaattagtta ttatacttat ttaaatatca atctttattg
     3721 ttccctgcat aaacaagact gcttcaccag aaattttcac agtattatcc ttcaacactt
     3781 cacactgaat tataccacca cgattagaaa gttgagcagc taccattttg tgttttccca
     3841 acttttcaga ccagtatgga ataagattac aatgtgatga accagtaaca gggtcttctg
     3901 aatctaattc tggacaaaaa tatcttgata caaaatctgt attacttcct tgtgctgtga
     3961 ttattatacc taaccagtct gtcaatttac gcaattgtgc gtaattaggt ttataattta
     4021 taacttcttg ttcactgttt agcaataaga ttaaatctct tgaagaataa acagcacttg
     4081 gtacacagcc tatcaaatta gcttgttgtg gtgataactc tatttcaata ggcattattt
     4141 ctggaaatat catttcatat agatttccat ttcgtgtaac ttcaagcttt ccactttgag
     4201 taaagaaatc tatccttttt acattaacat caataaaatt tgatattaca taagctgctg
     4261 ctaaagttgc atgaccacat aaatcaattt ctgctttagg agtaaaccat cgtaattcat
     4321 aatttccttt acctttaact acaaatgctg tttctggtaa attgttttct tctgctattt
     4381 tctgcattaa ctctaaaggt attcttctgt caagaacaca aactccagca ggatttcctt
     4441 taaatagttt agttgcaaat gaatcaacta tgtagtattc cattatttaa cctctctttc
     4501 taacataaaa tatacatcaa tttacattca ataaaacttt aaatttctta catatatttt
     4561 ttaatattac tctgttcaac aactttttta cctaacaatg taattgcttt tttagcacaa
     4621 ttatttacac aacgataaca cattgtacat tgcccatttg caacaatcat acaattttta
     4681 attactagat tcttcattgg acataaatta acacatttac cacatacaat acattcctca
     4741 gtattaattt ttagtttatc tgtatacata tttgttttgt tgataaaata caatcgttgt
     4801 ccaaataacc ctacaatatg actcaaaaaa cctaaccctt cttttggtgg tgacccatgt
     4861 ttcagttttt tagcagcttt agttactttc ttttctgctt ttattacaag ctttctatta
     4921 tactctaaag aatgttttaa taccttttca tctcctatac tatctggcat cttcacatgt
     4981 aatccaccaa cagttatagc accgtatttt tttaatattc tagataacac accagagcca
     5041 tctccactaa atagagccat agttgcaata ataaaaacac gtttaccatt ccacaaagtt
     5101 gaatgattta ttataaaatc tttcaatatt tttggcacat tactatattg caccggataa
     5161 ctaaaaataa tattctcatg attattgatg tgctgtaaaa gttcattatc ttcaatagaa
     5221 taagaatttg ctgttatatc atattcttgt aaaaattttt ctacacagta tcttgaattt
     5281 cctgttccac taaaatatat tcctatcata gtaattctcc taatagctaa gattatatag
     5341 ctctattctt aaaattctga ctttttatat tatctaaatt aagtagttta tttaaataat
     5401 ataaacttaa ttcaacaagt tacctactga acctcccatg actaaagtca tagggttcct
     5461 gcttgataga attttgcata gtcaatttac taaatacttg tctaattctt tttttatcat
     5521 tttaaatata cattttaata atattagtaa gctatacttc cttaagcata tattttccct
     5581 aaagtaaaac tattgatgat tattccatta tataacctaa ttataaattc agtaagttca
     5641 tcacatacta tacccttaat tctcaattat aaagtttcct aaaaaatact tgaaaattta
     5701 actatgaaaa aatttcctat tgcctaatat gtataagtaa ggagtactat atagtactcc
     5761 ttatattgta ctcttataac attgatgcct taatattatt ttaatcttaa tcattattga
     5821 tttgatttaa aattataaac aagttccaat attttaatta tgtcaactat atctcttata
     5881 gttttaataa tctcatcaat tggtttatgt gcttgttgca ctttatcaat agtattaatt
     5941 aaatccattt acacatctag cacctgtatg gcaatttagc attatcctta tcttatactt
     6001 tgttgtaaat tcttgattac ataattctat tatctaactt atagctgtgc aatctacatt
     6061 atctgtaaat actttgcttt atatattttc cctgaacctc taacattaat ataacagcct
     6121 ttttgctata cacttttaac tacatactta attttaataa cattacttgt ttataaaaat
     6181 atactataga taaatttcac ataaaaataa taattcaagt attgattttt atataagcaa
     6241 atttgtaatg tactaaaaat aacataaaag tttccatttt tcaatatgta agcttttatt
     6301 atgttatttt attgttaaag gtttcaagtt tttatttatt cattttaaaa aaattattat
     6361 ttttgtaaaa ctaatcccat agtcatacta tcgtcagaat atgcttcacc cttaacatta
     6421 ctaaaaaact caacagactt aaatccaata ttttcaactt ctaataagaa actttctttt
     6481 gaaaaatagt gattccaaac ataaaataca ttttcatctt tttcggttat tacaagagtt
     6541 tgttctaatg tattataatc attgtattta caattatctt gtagacacat atatttttca
     6601 ttactccaaa atcctccatc ttcatttatt tcccaatatt taatttcctc aaaattattg
     6661 tatttattta ttgtaaatac atctaatatt aattttcctc caggttttaa actatcataa
     6721 attttttcca ttaataacct tctattttca gttgacaaag ctccataatc acaataaatt
     6781 aaagtagcca aatcaaattc ctcattatag ttcatattta aataactttg gaacaagtaa
     6841 tttatgttta aattagtctc cttatttcta ttttgtgcat agttaataga acgttttgag
     6901 aaatcaattc cagttacctt ataacctttt tgtgcaaatt tctctgcata taaacctgga
     6961 ccacaaccta aatcaagtaa tttaggataa ttagctggat ttgcaactgt aactatccaa
     7021 tttacagaat cctcgataaa gttaaaattt ctacttgctc cttcaaaatt agtgtctaag
     7081 tgtgctttta ataattgctt tgaaatatac tcatcatccc aaaaattaat ttcactttgt
     7141 ttataaagct ctggtctttc taaatacata cataatttgt ttaacaaaac ataccactcc
     7201 ttaaaattta tttttaaaat aaaaaaacca cagagtttac tctgtggttt aacttcaaaa
     7261 agatgagttt aaataagagt aaaatagaac caaatatttt taagcacaac aataaaacta
     7321 tagctttact ttgtttgctt attaaatttg attttattca ctcttttcca gcaatactta
     7381 tatcaacgat tttatgatat caaatatcac cgaacaacat catcctttca tatttttatt
     7441 ttatgaatta attatatatt taaattttat atttgtcaat aaattttaat tttaataaat
     7501 tttaatcatc atagtaaaaa aaattttttt atataaaact aatcaaaaaa agatatctgt
     7561 acatctcctg agttttttaa cttttccttc attattttag agtaactgct tgatagagaa
     7621 tacttatatc taagttcatt aaccatttta tacaattgat ttttatactc cctattaagt
     7681 gaacctgcac tatatagtat tgataattta tcaaataatt caggaaactc ttttttaaca
     7741 aagtcaaaaa aaacacctct agttataccc cttaagtata aagtcccagg taaaacataa
     7801 tgtacattac attcttttgc atgtctaaat agcgaattta tattatcaaa atcatctgta
     7861 atatatggta taattggcat aatatgtaga ccaactgatg cgttagtttt tctaaattct
     7921 tttaacattt taaatcgtct cattgaatcc acaccatttg gctcaataag cctttgtgta
     7981 tcttcattta ctgtggtaat tgtagatgct acattgatat atgtaatcct agatagctta
     8041 tcaattaaat cgtaatctct taaaattaaa tctgactttg tagaaataat agctggtgtc
     8101 ttgtatttta ttagcaggtt taatatttct ggcataattt tatagtcagc ttctattggt
     8161 tgataactat ctgtaactcc tcctatattg attacttctt tcttccattt actgctttta
     8221 agttgtctct caagtttttc tactatattt gtttttacat aaatctcttc aaaataatta
     8281 ttggagttga tgtacttatg agagtaaata gcataacaat atttacatcc atgctcacat
     8341 ccacgataaa tatttaaatc ccatttatat ggcatactcc tttttaattt attacaagct
     8401 atttcacaat ttattggaat atattttatt ttattataca aataatcacc tctttatata
     8461 caataatact ataatgttaa tctatagtaa ttaaaacatg atatttccag accacaattc
     8521 ataatcttta ctatatttac aaagtaatat attccattca tttattggta ttcctccaca
     8581 tgttgctttt tcttctaaat tatataagca ttgctttaaa tacattttat tatgccaatc
     8641 atcatataaa ttttctaaat ttaaactatg ttcattagat atatcatttg caaaatttct
     8701 atttttccat tttaatatac ttgtatattt aagttcatta ggtttataat ttctttttaa
     8761 catttcatca tgtacaattt ttgtataaaa tttaaattca tctatactat aattcaatac
     8821 tttattcact aatagatggt ttggagtacc ttttttatct atagaacctt ttatagcaag
     8881 tagctctctc cattgactta ctaattgatt tttaggtaat acatcaatta aatccttatg
     8941 ccataatctc ataatttaac tccttactat aaaatatttt ataaattcaa taaccaatct
     9001 atcttacaat tttacatgtt caataatttt atctgtaaaa actataccat ttaaatggtc
     9061 tatctcatga caaagacatt ttgccataaa acctgaacct ttaatttcta ttttctcacc
     9121 gtattcgttt agagcttgca ctgtaacttt ttttggtctt tttaatttac cccatacttc
     9181 aggaaaactt aaacatcctt caacaacaat ttgttcccct tcttgttcaa taatttcagg
     9241 attaacaagc ttaataagtc cttctcctaa atctataaca actaatcgct ttaatactcc
     9301 tacttggcat gcagctaatc ctcctccatt tggagtattg tacatggtct ctgccatgtc
     9361 atttaatatt tctcttatct tattatctac gttttctaca tacttactct tttttcttaa
     9421 aatttcatca tcaaatgttc ttatctttct tatagccata atattctccc ctacttatct
     9481 gtgctcttga ttttctttca ctttcttcaa ataaaaatac actttcaatt ggttcattaa
     9541 aaattcttga aatatcatat gccaaccata ttgaaggttc atttttacca gtttctatag
     9601 catttatagc ctgtctagat gttccaacta atctccctag ttgttcttgt gtcaatccta
     9661 atttttctct taatatcttt attttatttt tcatatttgc tccattcatg taaggttaac
     9721 tttacatctt aaatgtaaca tttttcaaca ttactgtcaa gtcaacctta catttatata
     9781 ttaaattttc ttatttaact atttttttac taaacttttt aaataataat aaaatccata
     9841 ttaatgatat aacaattgaa ataaacatat agacataatt atcttcctta aatgccttcg
     9901 atatccaaaa agttggtaag aagaacagaa tatattgtgc tttatttaaa ataaaaaatg
     9961 gtgctaaaat acccatcata aaaacacctg agaatttcgt aattaccatt ccttctagtt
    10021 tatttgatga taaagaaatc actaatattg atataataac tccttgtaat aaaactaata
    10081 aagaaattga taagtttaac aagagagaaa ttttagttag agaaaaaaag ataagtagaa
    10141 tcatagtaat aataaatgct aagatacctg gtattccaaa tcgtgaaata agataaccag
    10201 ttttaccaag cggagttact attaaatatc ttgaaatgct gtcatcaatt tctcccaata
    10261 tgaccattgt agaagcaaaa aagaacataa aaggtgtaat aaaagctaaa agtaaatcaa
    10321 acatcaagaa atacggctct aaatttaatt gataataaaa cttgttaagt gatatattct
    10381 gtattaatgg tattccaaat tttataaata ctccacataa tattggagaa acacatacta
    10441 taaaaagcat agcatctctc ttaatttgtt caaactcttg tttaaacgca tttataatct
    10501 ttatcatagt tttactccac ctaccttttt ccaactgcta caaataaaat aataagttat
    10561 aaaataaatt attattataa ttgatattaa aattaaaata ttaatcatta taaaattttt
    10621 atctccacta ataagagaaa tacatatatt aaaagggtac aaatttgcat atgattttgt
    10681 gtcaagaagt acattcagta ttggtggaat aaagcatata atctcaatag gaatacttaa
    10741 aacaataaac tgattcaaac tagatgcttt acttgcaatt atcaatccaa gcaaagaaaa
    10801 tataatagaa gaaaaaaagg tacctatagt tgatattata atattatcta aatttaatgt
    10861 aatagcaata aacatagcta caatactaga tattactcct aatgaaatta cctttgataa
    10921 aatatactca gatactttta ctggagatac agctaaggaa tttaaaaccc tttgactttt
    10981 ctcaagaagt acaatagctc ccataaaaaa caatcccatt gctgctgggt cagaataaat
    11041 cataattata gctatttttt ctctcataaa agttggaaat acattgataa tacaaatata
    11101 tataatactt aaaaaaagat ataaaaaata aaaaccatac ttaaattgaa actttatatc
    11161 tcctaaaata agatttttta gcctcattgt aaattcctcc ctgttatctc aataaaaata
    11221 tcatttaatg ttggttcact actatgtatt gataaaagtt tatttttctc aataagcata
    11281 ttcaaatttt tatcattagc agtattgttc agaaaacatt cagaagtttt ttctccatta
    11341 tcaaagtaag tatatctaac tttaatagct ccttttgaca taataagatt atgtggtgta
    11401 tctaaagcag atattttacc atttacaatg aacgctactc tgtcacaaag ctctgttgca
    11461 tctaacatgt tatgagttgt taaaataata gtcttacctt tcgatttttc tgataaaatt
    11521 atatctttca taaccttgct atttgatggg tcaagaccac ttgttggttc atctaaaaat
    11581 aaaatatctg gattatgtaa taaagctttt ataaaattta atcgagattt catacctttt
    11641 gaatactcag ataccctttt atttgattca ttttctagtc ctactgattt taataactca
    11701 tcaatagata gtagtttttt agaatataga gacccaaaat attttaaatt ttctattgca
    11761 gtcaactttt catataaact aggaaattca aaatcaactc ctatattttc ataaaattta
    11821 tttgagtgtc ttttactctc tactccattt acaatgacac ttcctccata attagttatc
    11881 attccaatta gaatcttttg taatgtagat tttcctgcac ctgatggtcc taaaaatcct
    11941 agtatttccc cttttcctac ttcaaagtta atattttgta aaaaatctct atctgtataa
    12001 ctaaatgata aatcatcaac tttaatcatt caatatcacc ctttcaaatt tttgactatt
    12061 ttgactatat ggtcaataaa atataatttt tttgtttgtt aataattttt aataaaagtt
    12121 attagcaaac aaaatttaaa ttctattcca taagttgtat aactaatccg tttatcatta
    12181 atcttaaagc atcttcaaaa caattacttc caacctcgcg cttatatagc atggtaagaa
    12241 aaactgctct aaatgctcca ctaaagcttt ctatgtcttt attttttgca tttggtatgc
    12301 aagatataat ctctccaatt tcaaagtcat catgtctaaa gtattcttca attatagaat
    12361 ctggtaactt tctcaccaat atctcaaatt ctccatttat catgagattt aaaattgaag
    12421 tactatcaac catcctatag aatttcataa atatatctgt caattgttca catgtaatac
    12481 tttcatctac tctatttatc tcatataaga tttctttttg tatagagtca tgtatatctc
    12541 ttaatacctc aaaaaagagt aattcttttg attgaaaaaa tagataaaaa gttccttttg
    12601 gtatttttac ccgttttaca agctcatcaa cagtagtttt tctaatacca tattgctcca
    12661 tacacaatct tgcttcttct ttaagtcttt ttattatata ctctctttct ttatcagaat
    12721 atgatttagg catcttttcc ctccagtttg actaaaataa tttatatagt caatataata
    12781 ctttttctat ctaatgtcaa tagtattatt agtatattta aaaataagct taaaaacttt
    12841 cgaaaattct gaattttata tagcattttt tattatctag tgttataatt aagatataaa
    12901 taatatatta ttctaatttt catatctatt tgcttatttt ttaacttagt ttctaataga
    12961 agtaatcata tttatctttt taaaagtttc aactttaata aaaaataaag gagttgattt
    13021 tatggctact actacaaaaa accgttttta cgattatgtt caagaaaact taaataaata
    13081 tgttgaagta cattcttact ttagcagttg tcctctatat ggtgaaatta tagaagcaga
    13141 tagcttatca attacacttt gctcaagata tatagatgaa tctaatccaa ctttaaatga
    13201 aacttacaca ttatatttac cattaagttc aataatatct attagaacac tataaaaagt
    13261 taattaaata tgggttattt atatataaaa tgtaagattt tctatatttc tatataaagt
    13321 aacccttttt tatgttttta aacttatact acataaattt aaagctgaaa acaaaacttt
    13381 acaatcattg attatcttat ttatcaataa tttgaagtaa ttattttcag cttttattaa
    13441 gataagttac taatacacac taatatatgt taatacttaa gtactctatt tagcactttt
    13501 taattttact aactctttaa atgcattttt atttgctcct ccaccaactt gagttacttt
    13561 ttctaaagtc ttatttttaa gaacttcttt ttggctatca gctaatttat caccaactaa
    13621 aattactggt gacccagttt ttgctcctaa aggaccaact gccaatccat ctattaaatc
    13681 attttgattc ttgattccat ttttaactac aaatgcattt tttaaagtat cttttttata
    13741 aaaattatct attatctttg aattagtttc gtctctacta ctaccagata atctagttgg
    13801 attttttaac ttactttcta gattgtttga tagggatgct gttcctccaa taatataaga
    13861 tttctctata tttaatgaat ttagaaattc atcagctcct tgcaattcgc tcttttcatt
    13921 tgcaagtatg attggtatgt tattttctgc tgctgcagcg cctacactaa ttgcatcagc
    13981 taatcctttc actccattta caactgctat ttgagataca ttttttatac catttaactt
    14041 ttgagctaat aataaacttg tcttgtatct atcacttcct gatattctct ctatcgatat
    14101 atttaagctt tttaattgtt gttcaatttc tttacttata gaattttctc cacctattag
    14161 gtatactttc ttagcaccta atctctgtat ctcagcttta gtttttgaat ttaaagcttc
    14221 tttttgtgtc aataatattg gtgaatttat agcagatgta aaaggagttg ctgccaatgc
    14281 atctactatt gaactgccat ttactaaaac tacattttct gaagaattga aaccattttg
    14341 actaactttg atagcagttt catatctatc actaccaatt aaagactcat ttgggatact
    14401 ctcaccagaa gacttttctg taacagcttt tatagtaaaa ttacacggat agaagttact
    14461 atctctattt atatcaaaga attttccagt attatctatg atataacttt cacctaaatt
    14521 agcttttgct ttaaatgtat catatcctgg tacatttgac tcagaaccta tagttgactc
    14581 tccatttttc ccctctatac tgactacaat tgcacccttt ccttctggta tatcaaaaga
    14641 atcaattgga actgttatgt atcctgaata ttgggcagta ccttctttta attttttcat
    14701 attgttttct tgaggtatac catttactac tggagcataa tatacttcat acttagctcc
    14761 tatactttca gttaagaaca ttacagattt tagagtttca tcgcctctat tgaaatcaaa
    14821 tacatttgca gctgttatct tttttgaaat taaaggtaca atacttgcat agtcatgttg
    14881 atacatcttc tcatcatcat ttggtttttt accacctttg attgaaaaat tatctatatc
    14941 agacataagt gtcttgtctt cataagatat ccagaaatat ccaccctcag aattataatc
    15001 tccccagcta ttttttatta accaagcacc attttttgat ggtctaatat ttgcattaaa
    15061 attatcttta gaatagttat catcccaacc tacaattgaa atagcatgat ttgtattaaa
    15121 actttttgtt ggacaataat atgaattttg gtcatcactt tgatatttaa tatcttcata
    15181 ataaccagat gttacagctc catactgtaa tatagcattt tttgtagaat ttatgtcatt
    15241 gcttacacac acagcatctg tcacattaaa aacagtaggt gctgtattca tattagttgg
    15301 tttttttgct ccttgtgctt tagatactct accattgtat gggatatctt tttctaattt
    15361 aggacctgac caagatgtta aatatcccat agcttcataa tttaaagcac cattcatatc
    15421 atttacagac catccatatt caccatctga agcccaccat cttaagtgtt cttctgataa
    15481 atcatagtct ccataattat ttaactttaa gaaactttct aaggttgcca ttgcagcaaa
    15541 atcccaacag attcctaaat cctcttgatt ttttattgat gtcataagac ctaattttct
    15601 agggtcataa gatgttggag ctgttcttcc tttactttgg atttgagtac cttccaactg
    15661 atatggattt ggtataatcc cattatattt ttctgtacat ccatttttag catcatttag
    15721 atattgttta tacgtctcac tgtattctgc tttttttatc tgattcaatg tattgctatt
    15781 gtcagctgat acaggaattg ttgacattac taaaatagat attaaaaaca gcgcaacaaa
    15841 ccttgttact ttttttgaag taaatttttt cacgctttct cccccttatt ttgagctaat
    15901 ttttaaaatt ataatgttat atatgactaa atatcaagta tttacaaata tacaatcatt
    15961 taaatcaatt ataccaaagt tttcctttat aaataaataa aataaaataa aaaactgaat
    16021 ttatttataa taaattcagc ttctcatttt ctttttatat gtttttatct aaatcctatt
    16081 acagcagctc ctaaagctcc tattatttga gtatcttctg caataaaaat ttttttaccc
    16141 agtatttctt ctatcatttt tactagttct ttactttttg caagccctcc agtaaatgca
    16201 acttcatcta ttacctcacc tcttgctaac attgaggtgg atttatttgc aatagattta
    16261 agtatccctg ctgctacctc tccagtagaa atgttttgag ctagaagact tacaatttca
    16321 gactcagcaa aaactgtaca catactagat atattaactg gttcatatcc tttagctaat
    16381 gtatctatac tttcaatatc gcttcctaaa aggttagaag taatctctaa aaatcgacca
    16441 gttcctgcag cacacttatc attcattata aagttaaata catttccatc tctatctaaa
    16501 tttataactt tactatcttg accacctaca tctaaaatag tccttatgtt cttgtttaaa
    16561 aagtaaatac ctctagtatg acaagttatt tctgttactt tcttatcagc aaaatccatt
    16621 actccccttc cataacctgt acctaccacc ttttttatat cttttttgtc aatttcacta
    16681 cttagcaact catagacctg tttagatgta cttttagggc tccatccagt tggtataatt
    16741 attttcttaa taattttttc accatcaaat agcacaccct ttgttgccac tgaccctgag
    16801 tcaactccta tactaaacat agttcctcct acttttattt attcctacaa catctctaca
    16861 aacgcttcaa atctagttct taattgttca gtatctgatt ttgaataatc agtttcaaga
    16921 gacataaatg gcttattttt ttcttttgta acaaattctc ttattctata actttctata
    16981 ttaaatgtat gacatgcttg taaaactaca tctattacag catctacatt atattcatct
    17041 attattctat ctaataattc aatacgattg tcattattca tcatacaaga acaacctata
    17101 tttatatatt tttgtgttaa agcatcatat acatcttcta tttcttcatc aaccaataaa
    17161 tcgtttgatc taatagctcc acaaagttca tatgcaacga ctgatgcccc tgcatcttct
    17221 aaagttttaa ctattttttc gcttattcca ccaataggag aacctgttat caatattctt
    17281 ggcttatctt tttgaacagg acattcacct ttttcatatc tttctttcat atcatctata
    17341 acttttctta aagaatgttt aagttctgca cggtcaaatt taaaacctgc ttgatataaa
    17401 acattatgta actcaaggcc tgtaagtgca gatggttgta atttaccaag tgcataaaac
    17461 tcttttaaaa gttctctttc ttcattttta tcttttatag cagttcttat atcttcttca
    17521 gttatagtta cacctaaaga tttctcaacc tcttctttta atcttatcat ttcatctttc
    17581 caaagtttat aggcaaattc tccttttgaa gtatttggca aatgcattac atatgttggc
    17641 ttaacttttg caagttcttc atacattttt ttcttaccat cacaagtggt ttctcctatc
    17701 aacaaatcag aaaaatagaa ataaggacag gtatctgtta ttgcatgtcc atagcttgat
    17761 ttaattaaag gacaaagatt tcttggaagc accctttctg catcaggtat tggctcttca
    17821 ctaacgccgc atacacctac tacagttgct ccagctgcca ttggaatttc aactggagta
    17881 aatgtacaga aaactccaac catctttttc ccactttcct taagttcctt tgcatttata
    17941 aatccttttt gtctagcttc attgaagcta tcaaattgtt ttggcaaatt tgtcatgaaa
    18001 atattcctcc caattacttc tcttcataat tcaatctctt cgtaattcaa tttgtatctt
    18061 aagcaataaa aactaaattt ttccattaaa atacaaacct ctacattaga ttctatcatg
    18121 ctttaccttt tatccataat tgtttttatc aatgcaaaat tagatacata tagatatatt
    18181 gtataactaa ttttttatgt tataattttt cttataactt aagctctcga atcctcaatc
    18241 tataagcaga cacagcagtt tcacataatt tatcaattaa ttttccattc acataaaatc
    18301 ctacaaatgc tcctattcca ggcattagtt gtaaaaactt agctaaatct aaataatccc
    18361 tatactcttg ttgaaatgtt ctccaatcaa aatcattgat gtcttctggt agactattta
    18421 catattcatc ccagttattc atcaatttaa aagttttgtt tatatgctgt tgactagaaa
    18481 aagccaactg taatatattt aatatataaa tcctttctct ataatcttta acatcatatc
    18541 catatattga agctacatca tataaaaatt tcactttaat acctaaaagc aaaggaaaat
    18601 cagataaacc taagaggatt cctcctgccc ctgttcctgc cccttcaatc attgctgtag
    18661 tcttgtaagt tttagctttt tctaaaacta atttttctct ttcttctaat gacatatttc
    18721 taagtggtgg ctttgtagca tatttatatc caaacagtac ggtttttgtc attactttta
    18781 tagaagaagt aattatttca tgatatttat ctggcaatac tccattaaat ttattctgta
    18841 taccctttga tgctttgtca aatatagaag gtttctttaa tatatttttc ttccattctt
    18901 caagttcttt tttgactagt ttaatataaa caacatcttc ataatctttc acattttttc
    18961 tcctaataca atgtattttt atcaatttaa tagcttaatt taaagtttaa atatttttat
    19021 ctattaaatt aaactattca aatactcttt agtttcttta tctgcaaaac tagcttctac
    19081 tgcatttcta taaattattt tatagtcttc taatcctagt ttaaaagtat caaatataac
    19141 atttagttct gaacttaaat ttatatctga tacagttcta ttatcagtat ttatacttac
    19201 atgtaaatta tctttataaa aagtataaaa tggatgtgct tcataagaat ctactgtctt
    19261 agtttgtaca ttactagttg gacataattc aagcaatatt tttttatctt taactaaatt
    19321 atacgccttt ttatggtctt taatttttac cccatgacca atcctatccg cctttaaaat
    19381 atttatagca tccaatacat tttctccact tgcagcttct cctgcatgta ttgtaacttt
    19441 atatccatat tctcttgcta atttaaaaac atctttatat tccttacaaa atccctcttt
    19501 ctctggacca cacaagtcta ctgctacaac acctttattt acaaatgatt tcccttcttc
    19561 aattactaat aatgcctctt ttgaggtcat tgttctcata caacctaata ttaaattgcc
    19621 ttttatatca taaatacttt cagcttctct aattccttca attataccct caattatatt
    19681 tttaacactc ataccttttt gggtgtgaag taatggtgca aatctaattt caatatattt
    19741 tacattttct ctacttgcat cttccaaaag ttcaaaagta attcttttta aattttcctt
    19801 agattgcatt acttttaagg gtaaatcaaa tttttctaaa tattcatcta gtgaagtaca
    19861 attaaaagaa acctttgcta atttttttat ttcatccata ttatttgaag gtaaatctat
    19921 tttctcttta atagctatat caagcatggt ttctactcta acacttccat ctaagtggca
    19981 atgtaaatct atcttaggta aattttcaaa cattttatcc tcctactgta cttataaata
    20041 atactatcaa cagattttta agtcttattt ctattatatc aatatactac ggtttttaat
    20101 tctaaaaaag tcatatctca ttaaaatatt ttaatttaat ttatgactat ctaattatat
    20161 ctactgattc tttttaatat acatttatta atatacattt gataataaaa tttcaataca
    20221 taagaattta agttatataa ttaaaacttt gaattacaaa ggaggactta ttttgattac
    20281 cttaagtttt gatatagtgc aaaccttgac actatctata ttcttctttt taattggtaa
    20341 tttattgaag aataaagtta actttttaaa taatttctgt atacctgcac cagtaatagg
    20401 aggtctatta ttttgttttc taaatttatt ttttaaatat tttaatatag cagatatatc
    20461 tataagtgga aatttaatgc caaatttcat aaccttcttt tttacaacta taggacttga
    20521 aataagcata aatcttataa agaaaggtgg tagtgtatta tttagatatt ggattttgtg
    20581 tggagtattg gcattttgtc aaaatatatt agctattaca atatcaaaga ttataaaact
    20641 tgaacctctt ttagggctta tgtgtggaaa tgtatctatg gaaggtggtc atggttattc
    20701 tgctgcattt ggacttacaa tagaaaatct cggtatagaa ggagcagttg gggttggatt
    20761 atctgctgca acaataggac ttattatggg tggtatattg ggatgtcctg tagctaaatt
    20821 tctaataaat aaatataaat taaaaccatc atcaaatata gacttgtcga ttcctagata
    20881 taatagaaat ctaaagagat ttggaagtaa attttttaga aataagaata ggataaaaaa
    20941 taataacttc tccgaaacaa taacaccatc tgtatttttg gaacaggttc ttctcatatt
    21001 tatttgtata aatacaggag aaattataag tagatgcttc tatataacgt ttaatatact
    21061 attaccctct gttgtaactt gtatgttttc ggctgttatt tttagaaatt taaatgataa
    21121 gataaatata ctagaattaa attttaaact tatagatttt ttaaaagaac tttcattggg
    21181 aattttttta actttatcac ttatgaatat agatttattt gaattatcta cattattacc
    21241 tcctattctc ttaatagtaa cttttcaagt aatctttata atcctatttt caatatttat
    21301 ttgctttaga gtacttggaa aagattttga ttctgccatc ataataagtg gtttgattgg
    21361 acatggaata ggagctactc cgaacgctct ggcaaatatg agttctttga cacaaaaata
    21421 tggtgattct ccaaaagcct ttttagttgt accattagta agtggttttt tgctagatgc
    21481 tattagtatc ccatgtatac tattttttat aaacatacta acttagtatg tttatttttt
    21541 gttatatatt gacaatttgc tctttttgtt atatattata aatataaagt ttgataatga
    21601 ttttcattag gaggtgttaa taatgactgt ttacaactta aaacttggac aaaagggaat
    21661 tatagacaat atagctggaa atgaaaaact tatgaagaga cttctagcct taggactaat
    21721 agatggcact gaagttgaag tgaaaaagat agctcctctt aatgacccta tagtgattag
    21781 atttagaggg tttgacttag ctattagaaa atctgatgca aaaaatataa atttaaaaaa
    21841 taattaatat ataataaaaa agagatttta aatctatttt caggccatca acattctatg
    21901 tgttgatgg
//
LOCUS       DAJMZY010000069        21757 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.069, whole genome shotgun sequence.
ACCESSION   DAJMZY010000069 DAJMZY010000000
VERSION     DAJMZY010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 21757)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21757)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21757
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.069"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            complement(263..550)
                     /locus_tag="OE968_002464"
     CDS             complement(263..550)
                     /locus_tag="OE968_002464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCP7219740.1"
                     /translation="MKILAVCGFGVGSSMVLKMTIQKALKQLGIECEVENTDINSARG
                     ADCDCIFTSQELLNELKGTCNVDVYPVKKYMDLAEVTEVVQTFLSDKNDKK"
     gene            complement(563..2482)
                     /locus_tag="OE968_002465"
     CDS             complement(563..2482)
                     /locus_tag="OE968_002465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HCP7219741.1"
                     /translation="MKERAKKILDFIIKNNNVTSQELQEKFNVSKRTIYYDILAINEQ
                     LGKSGNIKNVKHKFIFEGNLCDARKIISTEEDKFLDSDYRKTFILNKILLGEKISIEK
                     LTNEMLLSKNTVVQTITDVKKYLQTMGLRLEYKGKYKIIGDEYVIRELFLIIVQENVL
                     EINSISEEVSSFDTKGHIKLTDYSLLNLTKFVEFLNKRIRDGKTLYSYKYLNEAKKIS
                     YFSNCKELLCEEANENEQAYICTYISSLPSLNSEVKEDVVEEYVDKLIDKFEVNTAIK
                     LESKHEFKKNILRHLHSSYNRIRFKFPIRNPMLDETKYKHESLYKIIKSIIENEEEFP
                     VFEGIREEEIGFIAAYFGGYLRGSRDNGLRRNKVLLVCPNGLMVSKSLEIQLYKYIPT
                     IEIVGIVSIKQLKEVNVYYDYIITTIDIQNVNNVIVVNPLLTSSDVQLLMNKLISVKE
                     NEKYFNLELIIQAIRKNGVINNEEALKADLLNIIHKIDEGEMYQPMLKELINAERVNI
                     IKNVRDWKEAIKIASKPLLEDNSIEELYIENMIKSVEKYGPYIVLADRFALPHASSKE
                     GVNKLAMSLLIVEDEVDLLGKPVNIFMVLAAVDNTTHIRALASLSEMMYEEENVKLII
                     NGDKSSIIELINKQN"
     gene            complement(2826..3350)
                     /locus_tag="OE968_002466"
     CDS             complement(2826..3350)
                     /locus_tag="OE968_002466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219742.1"
                     /translation="MKIDLEMIELFEQLEEIFRSASTIPFSHKCTVDKDEVLAIINDI
                     RTLIPEEVTQAVWINKERNKIISQAKQDATNIVEQAKKEAERIQQEYQDNIEELKKNS
                     EDVVKAYVESSEPVVQADQRAKDIVDRAERIANEIRIGSIEYAEDVLSSVEYNLREIL
                     EEVKRDKAELRPKK"
     gene            complement(3354..3851)
                     /gene="coaD"
                     /locus_tag="OE968_002467"
     CDS             complement(3354..3851)
                     /gene="coaD"
                     /locus_tag="OE968_002467"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HCP7219743.1"
                     /translation="MENKPRKAIFAGSFDPITNGHLDIICRASKLFDELQIGVLNNPN
                     KKGLFSFDERVKLIEKSTSHLNNIKVVTFDGLLINYCQENGIGALVRGVRSGADVDYE
                     LQMAHMNRELNPDIETIILPSCTKYSFISSSLIKEVLLFDADIKNLVPKIVLEELKKK
                     TSGGN"
     gene            complement(3853..4407)
                     /gene="rsmD"
                     /locus_tag="OE968_002468"
     CDS             complement(3853..4407)
                     /gene="rsmD"
                     /locus_tag="OE968_002468"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HCP7219744.1"
                     /translation="MRVISGKARGLKLNTPKNEDVRPTTDRVKESLFNMINSYIMESE
                     VLDLFAGTGSLGIECLSRGAKSCTFVDISKESIDIVKSNIKKARVESESIILNLDFKT
                     AIDKLKLQNSKFDIIFMDPPYYKNMFIEAIEKIDNSNLLNEDGIIVVEHDTNDLFPDK
                     ICKLEKTRDKKYGNTTLTFYKMEA"
     gene            complement(4466..6523)
                     /gene="recG"
                     /locus_tag="OE968_002469"
     CDS             complement(4466..6523)
                     /gene="recG"
                     /locus_tag="OE968_002469"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HCP7219745.1"
                     /translation="MDLYKDVQYVKGIGPKKADKLNKLGIFTLKDLLYYFPRQFEDRN
                     NLKKIAQLEDGEKVTIKAVISSINTFSPKEGMTLTKIDVKDETGSAKLVFFNKSYIKN
                     TFRPGDSILVFGKVKKKFNNLELTSCELEYLTNSPKNTCRFMPVYQLTYGVTNKEIMS
                     IIRTVLEDKELIIQEYMPQRIIEKYRLCSIDFAVRNIHSPSSKESLKIALYRIVFEEL
                     LILQLGLFVFKSGRNKEDGIKFETSKDLKKIISALPFKLTKAQNRALDEIIQDMNLEK
                     IMNRLVQGDVGSGKTVVALLALANCVLNGYQGALMAPTEILAGQHYISLTESLKDFGI
                     NVGLLIGSLTKKQKDTVLEQIKNNEIDILIGTHALIEDKVEFNNIGLVITDEQHRFGV
                     MQRSKLSLKGANPDILVMTATPIPRTLALILYGDLDISIIDELPPGRQPIETIAIEKS
                     KRDRAYNNLVRREVESGRQVYIVCPLVEESEAIEAKSAVELVEELRAEYFHDLRLGLL
                     HGKMKSSEKDEVMRLFKDKEIDILVSTTVIEVGVNVPNATLMIIENAERFGLAQLHQL
                     RGRVGRGSHKSYCVLIYDSKTDVCRQRMAIMEETNDGFKISEKDLEIRGPGEFFGTRQ
                     HGLPELKVANLFKHIKILKLAQQEARYILGEDNNLQLKENMALKKEIIDKFKDTLKEI
                     SLN"
     gene            complement(6604..8247)
                     /locus_tag="OE968_002470"
     CDS             complement(6604..8247)
                     /locus_tag="OE968_002470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HCP7219746.1"
                     /translation="MIQYIDGKRLREMFISGANNLQNNKELVDKLNVFPVPDGDTGTN
                     MSLTISYALKELAKVENDNISDIGKALSKGSLMGARGNSGVILSQIIRGIAKSIEGKS
                     KLSTEDLAKAFKNGSDTAYKAVIKPIEGTILTVVRESGEFAIKTAKKEKDVVKFLSML
                     VKESNSSLERTPDLLKNLKEAGVVDSGGKGLVLIYEGMLASIKGDNIEIKNVDLDTNI
                     STSMDFAKSTTSTDDIKYCYCTEFILESSKVEDTKIRDIMMAYGDSLAVVGDDGVIKV
                     HVHTNDPGNVLQEALKYGQLLTIKIENMKLQHENTLLDVEEKKENDSEPLEEEKEFGF
                     IATSMGEGLANIFKDFGVDHIIEGGQTMNPSTEDFMNAIKHINAKNIFIFPNNSNIIM
                     AANQAKELSDKNIIVIPTKNTPQGFAALVTFNGELSEDENKEAMMNALNSVKSGQVTF
                     AVRDTVMNEIDVKEGNIIGIAEGNLLSAGDYVDEVTSNLIEKLVDEDTAIITLFFGED
                     VTESQANELRTSLEEKFEDVDVELYYGGQPLYYYLISVE"
     gene            complement(8266..8616)
                     /locus_tag="OE968_002471"
     CDS             complement(8266..8616)
                     /locus_tag="OE968_002471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HCP7219747.1"
                     /translation="MSAKVTNQYGNIEIDNQVIAQVVYRAAMESYGLVGLAYKSKGIV
                     ELLKGENATKGVRVEEVEEDAIAIELYVIIQYGTNISTVANNIIDRVKYVVEKMTGVR
                     VTRIDINVQGIRVK"
     gene            8977..9165
                     /locus_tag="OE968_002472"
     CDS             8977..9165
                     /locus_tag="OE968_002472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HCP7219748.1"
                     /translation="MAKVCSVCGKGKVSGNQVSHSNKHNKRTWSANLRSVRAIIDGAP
                     KRVKVCTRCLRSGKIERA"
     gene            complement(9325..9477)
                     /locus_tag="OE968_002473"
     CDS             complement(9325..9477)
                     /locus_tag="OE968_002473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate translocator"
                     /protein_id="HCP7219749.1"
                     /translation="MRNNKSKVLLGILCLATGMAVILSMLLPGWIWSALTALILIGCG
                     ALLFFC"
     gene            complement(9575..10051)
                     /locus_tag="OE968_002474"
     CDS             complement(9575..10051)
                     /locus_tag="OE968_002474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HCP7219750.1"
                     /translation="MNLKRSNEKREEYRRMYSDKESFLSLIQNFTSVSIAKELTLKNI
                     ELETSFICEYKGKEVDIIYKVFSKSGKVSHYIVLEFQTEMDTEIVPRLKSYREQIWKS
                     FIMKKSLEEIEDKNFKLPKVIPVVLYSGPERLSRKKGILDIVESISEFSNNSSMKN"
     gene            10270..11031
                     /locus_tag="OE968_002475"
     CDS             10270..11031
                     /locus_tag="OE968_002475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HCP7219751.1"
                     /translation="MEYTVQKLSKLAGISTRTLRYYDEIGLLKPLKINSSGYRIYGQN
                     EVNKLQQILFYRELGINLENIKNIINSPNFDSLSALKEHHNKLLAKRKQIDLLIENVT
                     KTIALKEGKYTMTDIEKFEGFKEKMIDENEKNYGTEIREKYGKDIIDTSNKKLKNMSK
                     QDYENWQNLNIEIISKLKKAFKTGDASSELAQEVAKLHHKWLSYTWNTYSKEAHSSLA
                     QMYVYDERFTSYYDREQPGLAKFLRDAIVIYTRDK"
     gene            complement(11291..13219)
                     /locus_tag="OE968_002476"
     CDS             complement(11291..13219)
                     /locus_tag="OE968_002476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HCP7219752.1"
                     /translation="MHKRLLTLFKLLNESDDRITCKTLSNHLKVSERTIRNDITSING
                     TLEKNGAIIKIKKGEGYYIDILNLALYQQYLALISDDIMDSSEIPDSPIERNQYILKY
                     ILYNNTYIKLEDLANSLYVSKFTILNDIKRIKPILSKYNLILVSKPYYGVKVEGKEID
                     IRRCISNNMINRNFENYIIGITDREIELFNNVDLIELQRVVLSEINKFNINFLDFNLK
                     NFIIHLAITVSRILDGYCLDNVLDVVLTDFQSNTTVENIFNYIESKYTIIISKADRVY
                     LYNHFITKSSLLDNVSNRVDTKIIEYVEEILEVINNQYTFDLRNDSVLFDDLVLHFKS
                     ILNSKSYNLNKVNPLINTIKSNYPLAFEITLNAIEKVFKNSIYSLTEDEIGYVSLHIG
                     AGIERFFQSNIKCKNVVLVCGSGYGSSRLLEVQLNKVFHDKINILQCLSFNQFLASEL
                     SDVDIIISTIPLNHDSIPIVLVDLKLLKKDIENISKSITNNSHIYSNLLDNFFDKNLF
                     IVNPKIKDKDELIKLMCNKLTQSEIVFPSFAESVFYRESLSSTNIDDFLAIPHPMELS
                     SIRTKICISILDEPIYWSEDSTVKLIMMLAINKDDYIKINSIYDILLKIIHDNDIRDS
                     ISNCNDFDNFLSIIKSIV"
     gene            13453..13905
                     /locus_tag="OE968_002477"
     CDS             13453..13905
                     /locus_tag="OE968_002477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HCP7219753.1"
                     /translation="MVLQEKYIFIDKDLKSKEEVLNFIADSAYILGITTNKEALLKDL
                     LKRENEFPTGIKDGFAIPHTKSVNVKEASILYIKTTNELEWKTLDDSKVRYVFSLLAP
                     HKNEGNIHLKTLSKLATCLMEDDFTNEVKNASDASHLVKYITNKMKEE"
     gene            13908..14216
                     /locus_tag="OE968_002478"
     CDS             13908..14216
                     /locus_tag="OE968_002478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HCP7219754.1"
                     /translation="MKIVAITSCIAGLAHTPMAAKALEQAASKMGHEIKVEQQGAMGR
                     VNTITKEEAQDADFILIASDQTISGMERFDGKKVIKVKIGIALKKPEAVLTKCIEAIS
                     "
     gene            14330..15436
                     /locus_tag="OE968_002479"
     CDS             14330..15436
                     /locus_tag="OE968_002479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HCP7219755.1"
                     /translation="MSKKNKSLLSELKGHLMTGISYMLPLVIGSSLVVAIPKLTALAM
                     GITSLDAYKNVSGFYHILYLMEQVGWTGIGLLNTVLAGFIAFSIGEKPAMGAGFIGGL
                     IASNTNAGFLGAVIAGFFAGYVCKFLKKKIKISGSASGMMPLIIMPLITVGLTGFLMS
                     VVLAGPLGNINTSLNAWVAEMCQNGTNSVVLALILGAMIGFDLGGPVNKAAWMAGNAL
                     LLEGIYLPAILVNCAIVIPPLGYGLATFIRKSKFSNALAETGKGNIVMGIIGITEGAI
                     PFTLTNPLKLVPVNMIGCALGVGLSALLGVHAIMPPVGGLYGFISIGSGWAYLVGAIF
                     GALVIAILSTTLVDFNEDETTENTEFDEIELDIM"
     gene            15511..18189
                     /gene="mngB"
                     /locus_tag="OE968_002480"
     CDS             15511..18189
                     /gene="mngB"
                     /locus_tag="OE968_002480"
                     /EC_number="3.2.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosylglycerate hydrolase"
                     /protein_id="HCP7219756.1"
                     /translation="MKKTKVHVVPHSHWDREWYFTTSRSKIYLMKDFQDILDILEEKE
                     DFKYFTMDAQASLLDDYLKWRPQDEYRIRDLVQRRRLVIGPWYTQTDQLVISGESIIR
                     NLYYGIDRCNEFGEPMRVGYVPDSFGQSAQMPQIYRGFGIDSSLFWRGVSDDMVDTTE
                     FIWKGSDGSKVLAVQIPFGYYYGGNIPEDDSDLKEYLKDIIGKLKVKASTNNVYFPNG
                     FDQAPIRKNLPDILKKANEIDNENEYEISDIENYIDSVRNERNEFTELKGEFLNAKHM
                     RIHKSIFSSRSDLKIMNNKLENYITNVLEPLLTLSYSLGNEYPHLVIKDIWKLMFENA
                     AHDSIGSCNSDTTNEDVYTRYKQARDLSINLLDLHMRLISTQIKNNNEEITLTVFNGF
                     PEVRNEVVEFDTYIPGQDFVIKNKNGKILNYIIKEKEDITNYILTQTIRLNPSKKIYI
                     PKTVYRAKIALSVKDIPPMGYTQLVFELDTKNKCEIETSNCKEIENKYYKITANKNGS
                     LEILDKESNKTYKNQAVIEDNGDDGDSYNYSPPRKDIYVSSLDSVSSVEVLKSNIQEE
                     MILKYSLTIPTSLEERAIGKVSVKMPVTMKITLEPKEQIIKFNVNIKNNQALSHRVRV
                     LFNTEIASKFSIADQQFGIIQRPTVLEKDLALWKRDNYSWQEKPITIEPMQSFVTLED
                     GQRGIALITGCVREYQIVGDNLDTIALTLFRSFGYMGRENLLYRPGRASGEKIIATPD
                     AQLLKELNFDFGLYIYNNKFDEANVANTAKRFLTPIQIYEYADFLNGRLIFAFNDEKQ
                     IYENEFSLMNVNNSNFTVSAIKKEEKGDGIVVRIFNGMKNEDAKGSLNINKNVNDAYS
                     AMLDEIYDNTSKLKVNTKTVEVNSLSHCKVQTIVIK"
     gene            complement(18506..20839)
                     /locus_tag="OE968_002481"
     CDS             complement(18506..20839)
                     /locus_tag="OE968_002481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HCP7219757.1"
                     /translation="MDTKLKKFKDKYIVTIIVFILMLSASLGMISQYSTIQASAKGGA
                     ENPFEQESFVDSIYKGSYVLYHNMKEEQEGKMIQPSKLFINEETMNYIKNVSKEKDTY
                     DGSETYYTDDSINADFNENFENWEHFIKASGKNLKYYLVDKESNFEFFNDNKELGVLD
                     TTKNDASKENSNENQSKNTEMNDEERQKQITDIKENYRFYVVMNFDKDGKVNIVDSYG
                     VNQKIINQMLLSKAREDLMDTSLGGNSISYKLSPIKNITLVYAVPKVISKGDSVEYGY
                     GNTYFDDGIISYISNVENNSYYKISGMILKIILAIVVIVALAFPYRKSKELLGFDTLS
                     RIPLEILFIALAIIQGLVDLYPTVIISNTLSGNYVEYLINNDISAKMASILVSLMNLT
                     YWFVIFSIIFVFIILLKHILNVGIREYFTKHTVTGMFFVWLKKAGKAVINQIRTINLK
                     EKPNKTIVTILGINLLIIVIMCSMWFFGIILALIYSVVLFKILSDYSKKTIYEYNQLL
                     DVTKKISDGNLDVNMEKDLGFFNPIKDELGNIQTGFKKAVDEEVKSQKMKTELISNVS
                     HDLKTPLTSIITYIDLLKDESITDENRKLYIDTLDRKSQRLQHLIEDLFEVSKANSGD
                     VYLNIVNVDIVSLMKQTLLELDDKLADSSLIVKNNFSNEKIILPLDSQRTFRVFENLI
                     INISKYAMPNSRVYIDILETDNKVNIMLKNMSASEIDFSVDDIMERFVRGDKSRNTEG
                     SGLGLAIAKSFIELQGGKMNISVDGDLFKVTITFNKN"
     gene            complement(20814..21530)
                     /locus_tag="OE968_002482"
     CDS             complement(20814..21530)
                     /locus_tag="OE968_002482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCP7219758.1"
                     /translation="MNSYNILVVEDEKEIADAIEIYLLNQGYNVFKGYNGLEGLKVIE
                     NQEIHLAIVDIMMPKMDGITLTMKLRENYNFPVIMLSAKSEEVDKIMGLNIGADDYVT
                     KPFKPLELLARVNSQLRRYTKYLNMVGNKEQKVESDDSVFAIGGLELNENTKEVSIDG
                     KYIKTTPIEFKILSLLMRNAGRVFSADEIYERVWNENAVNTDTVMVHVRNIREKIEID
                     PKNPKYLKVVWGVGYKIEKI"
BASE COUNT         7461 a         3428 c         2576 g         8292 t
ORIGIN      
        1 cagcaattca agtagtattg gataggttct atcctatctc tacatatagg tttccctata
       61 tgctgactat tttagctact aactcatgac taaggtcacg agtgtgcgta gctatttttt
      121 aatcaagcat tatatttttt agtgataggt caactgttta agttttctac cactaaatcc
      181 ctcctctctt tcttactatt tttgaactta gtaagttttt attttattct gattaactta
      241 aatttacttt ttaaaactta tactatttct tatcattttt atcacttaaa aaagtttgaa
      301 caacttctgt gacttctgct aaatccatgt actttttaac tggatataca tctacattac
      361 aagttccttt taattcattt aacaattctt gacttgtgaa tatacagtca caatcagcac
      421 ctctagctga atttatatct gtattttcta cttcacattc tatacctaac tgctttagag
      481 ccttttggat tgtcattttt aataccattg atgaacctac accaaaacca catactgcta
      541 atatcttcat ttttcattcc ccctaatttt gcttatttat aagttctatt attgaacttt
      601 tatcaccatt aattattagt tttacatttt cttcctcgta catcatctct gatagtgatg
      661 ctaatgctct aatgtgagta gtgttatcta cagcagctaa taccataaat atatttactg
      721 gttttcctaa taaatcaact tcatcttcta ctattagtaa agacatagca agcttgttta
      781 ctccttcttt agaacttgca tgtggtagag caaatctatc agctaaaaca atatatggtc
      841 catatttctc aactgacttt atcatatttt ctatatataa ctcttctata gagttatctt
      901 ctaacaatgg ctttgaggct atttttattg cttctttcca atctctaaca ttttttatta
      961 tattgaccct ttctgcatta attaattcct ttaacattgg ttgatacatc tctccttcat
     1021 ctatcttgtg tattatgttt aataaatcag cttttagtgc ttcttcatta ttgataactc
     1081 cattttttct tatagcttgt attattaatt caagattgaa atacttctcg ttttctttta
     1141 cacttattag tttgttcata agtaattgaa catctgatga tgttaaaaga ggatttacaa
     1201 caattacgtt gtttacattt tgtatatcta tagttgtaat tatgtaatcg tagtatacat
     1261 ttacttcttt tagttgctta atggatacta tacctactat ttctatggtt ggtatgtatt
     1321 tatatagttg tatttccaaa ctctttgata ccataagacc attaggacaa actagtaaga
     1381 ctttatttct tcttagacca ttatccctag accctcttaa atatcctcca aaatacgctg
     1441 ctataaatcc tatttcttct tctcttatcc cctcaaatac aggaaactct tcttcattct
     1501 ctataattga ttttataatt ttataaagtg actcatgttt atacttagtc tcatctaaca
     1561 ttggatttct aataggaaac ttaaatcgta ttctgttgta agaagagtgg aggtgcctta
     1621 aaatattttt cttaaactca tgcttacttt ctaattttat tgctgtattt acttcaaact
     1681 tatctataag tttatctaca tattcttcaa caacatcttc cttaacttca ctatttaagc
     1741 tgggaagtga acttatgtaa gtgcatatat aggcttgttc attttcatta gcttcttcac
     1801 ataaaagttc tttacaatta ctaaagtaac taattttttt agcttcattt agatatttat
     1861 atgagtataa tgttttccca tctcttatcc ttttatttag aaattccaca aacttagtta
     1921 gatttaataa agaataatca gtaagtttta tatgtccttt tgtatcgaaa ctacttactt
     1981 cctcacttat agaattaatt tccagtacat tttcttgaac aattatcaga aacagctctc
     2041 taataacgta ttcatcacct ataattttgt actttccctt atactctaat cttaacccca
     2101 ttgtttgaag gtattttttt acatcagtta ttgtttgtac tactgtgttt tttgaaagta
     2161 acatttcatt tgttagtttt tctattgata ttttttcgcc aagtaatatc ttgtttaata
     2221 taaaagtttt tctgtaatca ctatctaaaa atttatcttc ttcagttgaa attattttcc
     2281 ttgcatcaca taaattacct tcaaatataa atttgtgttt tacatttttt atattaccac
     2341 tttttcctag ttgttcattt atagctagaa tatcgtaata aatagttctc tttgaaacat
     2401 taaacttttc ttgtagttct tgtgatgtta cattgttatt tttaataata aaatctaata
     2461 tttttttagc cctttccttc atactacctc cttaatttta ttatctatat tttctacatg
     2521 tagtgccata ccaaataatt gcacatgatt tagtattatt ttataatttt gcacagtcta
     2581 actctaatct aaaagaagac agtggtaaaa ttattaaaaa aatttgaaaa taacctatat
     2641 tatttataca aataaataag ttgatttcaa caaataaaag attaaactac attataatat
     2701 caaaataaga tataagtaat ctaaaaagca caattatata acaaaaaatt gctatattaa
     2761 aagagagcta tcacacataa attggaattt tttgtgtgat agctccattt ttatttattt
     2821 aaaatttatt ttttaggtct aagttcagct ttatctcttt ttacttcttc taatatttct
     2881 cttaaattat actcaacact agaaagcaca tcctctgcat attcaattga cccaattctt
     2941 atctcattgg ctattctctc agctctatca actatatctt ttgctctttg gtctgcttga
     3001 acaacaggtt cactggattc tacatatgcc tttactacat cttcagaatt tttctttaat
     3061 tcctctatat tatcttgata ttcttgttgt attctctcag cttctttttt cgcttgttca
     3121 actatatttg tagcatcttg cttagcttga cttattattt tatttctttc tttattaatc
     3181 catactgcct gtgttacttc ttctggtatt aaagttctta tatcattaat tattgctaaa
     3241 acctcatctt tatccactgt gcatttatgt gagaaaggga ttgtagaagc acttctaaat
     3301 atctcctcta actgctcaaa tagttcaatc atttctaaat ctatcttcat atatcaatta
     3361 cccccactag tttttttctt taattcttcc aaaacaatct ttggaaccaa attttttata
     3421 tcagcatcaa agagcaaaac ctcttttatt aaagatgaac ttataaatga atattttgta
     3481 caacttggta aaattatagt ctctatatct ggattaagct ctctattcat atgcgccatc
     3541 tgaagttcat aatcaacatc agcaccactt ctcacacctc taactaatgc tccaatccca
     3601 ttttcctgac agtaatttat taataaacca tcaaaagtca caacttttat attatttaaa
     3661 tggcttgtac ttttttctat aagttttact ctttcatcaa agctaaatag acccttttta
     3721 ttaggattat ttaatactcc tatttgtaat tcgtcaaata acttcgaagc cctgcaaata
     3781 atatctaaat gtccattagt aattgggtca aaacttcctg caaatatagc ttttctaggt
     3841 ttattttcca tattatgcct ccatcttata aaaagttaat gtagtatttc catatttctt
     3901 atctctagtt ttctccaatt tacatatctt atctggaaat aaatcattcg tatcatgttc
     3961 tacaactatt attccatctt cgttcaatag attagaatta tcaatttttt caatagcttc
     4021 tataaacata tttttataat acggagggtc cataaaaatt atgtcaaatt tactattttg
     4081 taatttaagt ttatctattg cagtcttaaa atcaaggttt aaaataatac tttcactttc
     4141 aactcttgcc ttttttatat tggacttaac aatatctatg ctttccttac tgatatctac
     4201 aaaagtacat gacttggcac ccctagataa gcactctatt cctaaagaac cagtcccagc
     4261 aaataaatcc agaacttcac tttccattat atatgaattt atcatattaa atagagactc
     4321 ttttactcta tctgtagttg gccttacatc ttcatttttt ggagtattta gttttaatcc
     4381 tctcgctttt cctgaaatta ctctcaatat gacaatctcc cttcagcaca ttattacatt
     4441 agtaatattt taacacaatt taaaattaat ttaatgaaat ttctttcaat gtatctttaa
     4501 atttatctat aatttctttt ttgagtgcca tgttttcttt taattgtaga ttattatctt
     4561 cacccaatat atatcgagct tcttgctgtg ctaacttcag tatttttata tgcttaaata
     4621 agtttgctac cttaagttct ggaagaccat gctgccttgt cccaaaaaat tccccaggtc
     4681 ctcttatttc taaatccttc tctgaaatct taaaaccatc attggtctct tccattatag
     4741 ccattctttg tctacataca tctgttttag aatcataaat tagtacacaa tacgatttat
     4801 gactacctct tccaactcgc cctctaagct gatgtaattg tgcaagtcca aatctttctg
     4861 cattttctat tatcattaat gttgcatttg gcacattgac accaacttct attactgttg
     4921 ttgaaactaa aatatctatt tctttatctt taaaaagtct cattacttca tctttttcac
     4981 ttgacttcat tttaccatga agcaacccaa gccttaagtc gtgaaaatat tccgctctta
     5041 actcctcaac aagttcaact gctgatttgg cttctatggc ttcactttct tctaccaagg
     5101 gacatacaat gtacacttgt cttcctgatt caacctctct tcttacaagg ttattatatg
     5161 ctctatctcg cttacttttt tcaatagcaa ttgtttctat tggctgtctt cctggaggaa
     5221 gttcatctat aatagaaata tctaaatctc catagagtat aagtgctaaa gttcttggta
     5281 ttggtgttgc tgtcattact aatatatcag gatttgctcc tttcaatgaa agtttgctcc
     5341 tttgcataac accaaatcta tgttgttcat ctgttataac taaaccaata ttattaaatt
     5401 caaccttatc ttcaattagt gcatgtgtac ctattaatat atcaatctca ttattcttta
     5461 tttgttccaa tactgtatcc ttttgttttt ttgtaagact acctattaat agacctacat
     5521 ttattccaaa atcttttaga gactcagtaa gtgaaatata atgttgccct gctaatatct
     5581 ctgtaggtgc catcaaagcg ccctgataac catttaaaac acaatttgca agtgctaaga
     5641 gagctactac tgttttacca ctccctacat caccttgtac caatctattc attattttct
     5701 ctaaattcat atcttgtata atttcatcta atgccctgtt ttgagcttta gtcagtttaa
     5761 atggtaaagc acttattatt ttttttaagt ctttacttgt ttcaaacttt attccatctt
     5821 ctttatttct gccactttta aatacaaaca accctagttg tagtataagt aattcttcaa
     5881 atacaattct atataaagct atttttaatg attccttact acttggtgaa tgtatgtttc
     5941 taactgcaaa atctatacta catagcctat atttttctat aattctttgt ggcatatatt
     6001 cttgtataat taattcttta tcttcaagta ctgttctaat tatactcata atttctttat
     6061 ttgtaacacc gtatgtaagc tggtacacag gcataaatct acatgtattc ttaggtgaat
     6121 tagtaagata ttctaattca catgatgtaa gttctaagtt attaaatttt ttcttaacct
     6181 tcccaaaaac taatattgaa tctcctggac gaaaagtatt ttttatataa ctcttattaa
     6241 aaaacactaa tttagccgag cctgtctcat cttttacatc aatctttgtt aaagtcatac
     6301 cttcttttgg gctaaatgta tttatacttg atattactgc ttttatcgta actttctcac
     6361 catcttctaa ttgtgctatt ttctttagat tatttctatc ttcaaattgt cttggaaaat
     6421 aatacaatag gtcttttagt gtaaatatac ccagtttatt taatttatct gcttttttag
     6481 gtcctattcc cttaacatat tgaacatctt tatataaatc caacaaatat atcacctact
     6541 acacaaaaat cctgtacaac caattttata aaagctactt ggtcatacag gttcttataa
     6601 tcattattca actgaaatta agtaataata aagaggttgt cctccataat ataactctac
     6661 atctacatct tcaaactttt cttctaaaga agtacgtagt tcatttgctt gagattctgt
     6721 aacatcttca ccaaagaata atgttattat agcagtatct tcatcaacca acttttcaat
     6781 aaggtttgat gttacttcat ccacataatc tcctgctgat aataaattcc cttctgcaat
     6841 tccaattata ttaccttctt taacatcaat ttcgttcatc actgtatccc taacagcaaa
     6901 agttacttga cctgatttaa ctgagtttaa agcattcatc atagcttctt tattttcatc
     6961 ttcgcttaat tctccattaa aagttactaa tgcagcaaat ccttgaggcg tattttttgt
     7021 aggtataact attatatttt tatcactcaa ttcttttgcc tgattagcag ccattattat
     7081 attgctgtta tttgggaaaa taaatatatt tttagcattt atatgcttta tagcattcat
     7141 aaaatcttca gtacttggat tcatagtttg accaccttct attatatggt caactccgaa
     7201 atctttaaat atatttgcca aaccttcacc catagaagta gctataaacc caaactcttt
     7261 ttcttcttct aaaggttcac tatcattttc tttcttttct tctacatcca gtaatgtatt
     7321 ttcatgttgt aacttcatat tttctatttt tatagttaat aattgaccgt actttagagc
     7381 ttcttgaagt acatttcctg ggtcattagt gtgtacatgt acctttatga ctccatcatc
     7441 tccaactact gctaggctat caccataagc catcattatg tctcttattt tagtatcttc
     7501 taccttagaa ctttctaaaa taaattctgt acaatagcaa tattttatat catctgtgct
     7561 agtagtactc tttgcaaaat ccatacttgt tgaaatatta gtatctaggt caacattttt
     7621 tatttctatg ttatcgcctt ttatagaagc taacattcct tcatatataa gtacaagacc
     7681 ctttccacca gagtcaacca caccagcttc ttttagattc tttagaaggt ctggagttct
     7741 ttctaatgaa gaatttgatt ccttcacaag catacttaaa aactttacta catctttctc
     7801 ttttttcgca gtttttattg caaactctcc actttctcta actacagtaa gtatagttcc
     7861 ttcaattggt tttattacag ctttatatgc tgtgtctgaa ccatttttaa aagcttttgc
     7921 taaatcttct gttgataatt tactttttcc ttctatagat ttagctatac ctctgattat
     7981 ttgtgaaagt ataactcctg agtttcctct agctcccatt aaagaacctt tagataatgc
     8041 ttttccgata tctgatatat tatcattttc aacttttgct aattctttta aggcataaga
     8101 tattgttaat gacatattag ttcctgtatc tccatctggt acagggaata catttaactt
     8161 gtcaactaac tctttattgt tttggagatt gtttgcacct gaaataaaca tctcccttaa
     8221 ccttttacca tctatatatt gaatcatttg tttcctccta tgaaattact taactcttat
     8281 tccttgtaca ttaatatcaa ttctagtaac tcttacgcca gtcatttttt caactacata
     8341 ttttactcta tctattatat tattggcaac agtagatata tttgtaccat attgtattat
     8401 aacataaagt tcgattgcta tggcatcttc ttctacttcc tcaactctta cacctttagt
     8461 tgcgttctcg ccttttaata gctctactat tcctttagac ttatatgcta aacctactaa
     8521 gccataactt tccattgcag ctctatatac gacttgagct attacttgat tatctatttc
     8581 tatatttcca tattgattcg ttacctttgc actcatggtt gaccccctta agcttatttt
     8641 tattaaaaac atttcttaat ttatttttta ctatttttac ttatttatta tataaaatta
     8701 taatcatatc atactataaa tatggtataa tttaaaccta gaaaagtttt tggataaaat
     8761 ttcttctata gtatatatat tcaaagaaaa ataataatta ttttccaaat atatttactt
     8821 tatataaaat tatatatata attttatatg ataataagaa attcttcaat atgtgtaagg
     8881 caaatatata tttctattgc aaatttttgt tatttatgat aatataaata tgtttttagt
     8941 ctttaaatag ttatcatttt aaggaggtgt gcgtagatgg caaaagtatg tagcgtatgt
     9001 ggtaaaggta aggtttctgg aaaccaagta tcacactcaa ataaacataa taaaagaaca
     9061 tggtcagcta acttaagaag cgtaagagcg attatagatg gagctcctaa gagagtaaaa
     9121 gtttgtacta gatgtttacg ttctggtaaa attgaaagag cttagtaacc acgtttaaaa
     9181 gcctacttcc gtaagtaggc tttttaattt aatcattttt actctttctc ataaatttta
     9241 ggattatact tgaaatccat tttggtaatt ttattgttac tactttcatc aatactcacc
     9301 ccacacttta tagttaaaac tattttaaca aaaaaataat aatgctccac atccaataag
     9361 tattaatgcg gtaagtgctg accaaatcca gccaggaagc aacattgaca gaattacagc
     9421 cattcctgtt gctagacaaa gtattcctag caatacctta gacttgttat ttctcatgga
     9481 acacctccac atagaacctg tatctataaa tattttcata ttcaagttta tgcgacagtt
     9541 ttccatttta gaccaataaa cacattatgt aattttaatt tttcatacta gaattattac
     9601 tgaactccga tatagattct acaatatcca aaattccttt ttttctactt aacctttcag
     9661 gtccactata taaaacaact ggtataactt taggaagttt aaaattttta tcttctattt
     9721 cttcaaggct ttttttcata ataaaacttt tccaaatttg ttctctatac gatttcaatc
     9781 ttgggacaat ttcagtatcc atttctgttt gaaattctaa cactatataa tgtgatactt
     9841 tgccactttt agaaaatacc ttataaatta tatcaacttc ttttccttta tattcacata
     9901 taaaagatgt ttctaactct atatttttaa gagttaattc ttttgctatt gagacacttg
     9961 taaaattttg aatcaaactt aaaaaacttt ctttatctga atacattctt ctgtactctt
    10021 ctcgtttttc attgcttctt tttaaattca tacagttcct cctagactat agaccctcta
    10081 ttttttagta aagatagtct ataaatttta ttttttaatt ttcattagtg agtattgaca
    10141 gttgtgtgta aaatatccag taaagatatt tttttatatt tttattaaaa gatataaatt
    10201 tttatatttt aatgtattga catttacgtt gcgtaaaagt gtatatttaa tttataggag
    10261 gtactactta tggaatatac agttcaaaaa ttaagtaaac tagctggtat aagtactaga
    10321 acacttagat attatgatga aataggtctt cttaaaccac ttaaaataaa ttcttcaggt
    10381 tatcgtatat atggtcaaaa tgaagttaat aaacttcaac aaatactttt ttatagagaa
    10441 ttaggaatta acttagaaaa tataaaaaac attataaatt caccaaactt cgatagttta
    10501 agtgcgttaa aagaacacca taataaatta ctagccaaaa gaaagcaaat tgatttacta
    10561 atagaaaatg taactaaaac tatagctctg aaggagggaa aatacactat gacagatata
    10621 gaaaaatttg aaggttttaa agaaaagatg attgatgaaa atgaaaaaaa ttatggaact
    10681 gaaattagag agaaatatgg taaagatatt atagatacat caaataaaaa acttaaaaat
    10741 atgtctaagc aagattatga aaattggcaa aacctaaata tcgaaataat tagtaaactt
    10801 aaaaaagctt ttaaaactgg tgatgcctct agtgaactgg ctcaggaagt tgcaaaatta
    10861 catcataaat ggttgagtta cacttggaac acatactcta aagaagctca ttcctctcta
    10921 gcacagatgt atgtatatga tgaacgtttt acatcatatt atgatagaga acaacctgga
    10981 ttagctaagt ttttaaggga tgctatagta atatatacaa gagataaata atataaaata
    11041 ataaaggtgg tgtctcaaaa tgaacttttt agttcatgag acactctttt ttgtatgaaa
    11101 tcagatatat ttttatcatt ttatcaatga aaaacaggtt tctctctcta ttttgagaca
    11161 gaatctttat tgtataataa ttataatcaa tacaaaataa taacaaatta tacaaaactt
    11221 acttatacta tttatgctaa aaacaaaaaa tattttatta aagtttttaa aacttatgta
    11281 atataaaaat ctatactata gacttgatta tggaaagaaa attatcaaaa tcattacaat
    11341 tagatatact atctctaata tcattgtcat gaattatctt taaaaggata tcataaatgg
    11401 agtttatttt tatataatca tctttattta tagccaacat catgattaat ttaacagtag
    11461 aatcttcact ccaatatatt ggttcatcca atatggaaat acaaatctta gttcttatag
    11521 agcttaattc cataggatga ggtatagcta aaaaatcatc tatattggta gaagataaac
    11581 tttctctgta aaatacagat tcagcaaatg atggaaatac aatttcactt tgagttaatt
    11641 tgttgcacat caactttata agctcatctt tatctttgat tttaggatta acaataaata
    11701 aatttttatc aaagaaattg tccaaaagat tactataaat atgggaatta ttagtgattg
    11761 acttagatat attctctata tcttttttta atagttttaa atccactaat acaataggaa
    11821 tactatcatg atttaaagga attgtcgata ttattatatc tacatctgac aattcactag
    11881 ctaaaaattg attaaatgat agacattgaa gtatatttat tttatcatga aaaactttgt
    11941 ttaattgaac ctctaataac ctacttgaac cataccctga accacatact aatactacgt
    12001 ttttacactt aatattactt tgaaaaaatc tctctattcc agcacctata tgcagggata
    12061 catatccaat ttcatcttct gttaaagagt aaatactatt tttaaaaact ttttctatag
    12121 catttaaagt tatttcaaat gctaaaggat aattactctt tattgtattt ataaggggat
    12181 tcaccttatt taaattataa gatttagaat tgagaattga tttaaagtgc agtactaaat
    12241 catcaaataa tacactatca tttctaaggt caaaagtata ttgattgttg attacttcta
    12301 aaatttcttc aacatactct ataattttag tatctaccct attggaaacg ttatccaaaa
    12361 gagaactttt agttataaaa tgattatata gataaactct gtctgccttt gaaataatta
    12421 tagtatattt actctcaata taattaaata tattttcaac agttgtattc gattgaaaat
    12481 ctgttaaaac aacatctaaa acattatcta agcagtaacc atcaagtatt ctacttacag
    12541 taatagctaa atggataata aagtttttta gattaaaatc taggaaattg atattaaatt
    12601 tattaatttc acttaacact accctttgaa gctctattaa atctacatta ttaaataatt
    12661 ctatttctct atctgtaatt ccaattatat agttttcaaa attcctattt atcatattat
    12721 tagaaataca tcttcgaata tctatttcct taccttcaac tttaactcca taatatggct
    12781 tagaaactaa tattaaatta tactttgaca aaataggctt tattcttttt atgtcattta
    12841 gtattgtaaa tttactcaca tacaagctat tagctaaatc ttctagtttt atatatgtat
    12901 tgttatagag aatatatttt aaaatatatt gatttctttc tataggagaa tctggtattt
    12961 cacttgaatc cataatatca tcagatatta atgctagata ctgttggtat aatgctaaat
    13021 taagaatatc tatataatat ccttctcctt tttttatttt aataatagca ccatttttct
    13081 ctaaagttcc atttatagaa gtaatatcat ttcttatagt tctctcactc acttttaaat
    13141 gattacttaa agttttacaa gtaattctat catcactttc atttaataat ttaaacaacg
    13201 tgagcaatct cttgtgcata aatatccccc cttatagaat ttcttctaaa ttatactatt
    13261 tacactcata taatacaatt actctaataa aattgtatta taataattta tttccacttc
    13321 tatatggaaa ttagttatta tcataatata aatttccatg tcgaagtgga aattagttat
    13381 atttaattta attaggataa tgattacaat ataaatataa gttaagacat tatgaatgga
    13441 gtggaaaaat atatggtact acaagaaaaa tatatattta tagataaaga cttaaaaagc
    13501 aaagaagaag tattaaattt tattgcagat agtgcttata tactaggtat tacaactaat
    13561 aaagaggctc ttttaaaaga ccttctaaaa agagaaaatg aatttccaac aggaataaaa
    13621 gatggatttg cgatacctca tacaaaaagt gtaaatgtaa aggaagcttc catactctat
    13681 attaaaacaa ctaacgagtt agagtggaaa actttagatg atagtaaggt tagatatgta
    13741 tttagtttgt tagccccaca taaaaatgaa ggaaatatac atttgaaaac tctatctaaa
    13801 ttagccacat gtttaatgga ggatgatttt acaaatgaag ttaaaaatgc tagtgatgca
    13861 agtcatttag taaaatatat aactaataaa atgaaggagg aataattatg aaaatagtag
    13921 caataacatc atgtatagca ggattagcac acacacctat ggcagcaaaa gctttagaac
    13981 aagctgcatc aaaaatgggt catgaaatca aagtagaaca acaaggtgct atgggacgag
    14041 taaatactat aacaaaagaa gaagcacaag atgcggactt tatacttata gcatctgacc
    14101 aaactatatc tggaatggaa agatttgatg gtaaaaaggt gataaaagtc aaaataggta
    14161 tagcgttaaa aaaaccagaa gctgtcttaa caaagtgtat agaagctatt tcttaataaa
    14221 aaaatctcac tctaatatag aatgagaaaa atcaaaaatt aaaaaattgt ctaatgtaat
    14281 tataacatat tatcaaaaaa tataacaaac ttatatagga ggattaaaaa tgagtaaaaa
    14341 aaataaatct cttttaagtg aacttaaggg acacttaatg acaggtatct catatatgtt
    14401 gccacttgta ataggctcat ctttagttgt agctatccca aagcttacag ctttagcaat
    14461 gggtataaca agtttagatg cttataaaaa tgtatctggt ttttatcata ttctttactt
    14521 aatggaacaa gttggttgga ctggcatagg tctattaaat acggtattag caggatttat
    14581 agcattttca ataggtgaga aaccagctat gggtgcaggt tttattggtg ggctcatagc
    14641 aagtaatact aatgcaggat tcttaggagc agtaatagca ggtttctttg ctgggtatgt
    14701 ttgtaagttt ttaaagaaaa aaattaaaat atctgggtca gcatcaggaa tgatgccact
    14761 tataataatg ccacttataa cagttggatt aactggtttt ttaatgagtg ttgtattagc
    14821 aggaccttta ggaaacataa atacttcatt aaatgcttgg gtagctgaaa tgtgtcaaaa
    14881 tggaacaaat tcggtggtat tggctttaat tttaggcgca atgataggat tcgatttagg
    14941 tggaccagta aataaagcag cttggatggc aggaaatgca ttattgttag agggaatcta
    15001 tctaccagcg atattggtaa actgcgcaat agttatacct ccactaggat atggtttagc
    15061 tacattcata agaaaatcaa agttttccaa tgcattagct gaaacaggaa aaggcaatat
    15121 agttatgggt ataattggaa taacagaagg tgcaattcct ttcactttaa caaatccatt
    15181 aaaattagtt cctgttaata tgataggatg cgctttgggt gtaggattat cagctttgtt
    15241 aggtgtacat gctataatgc ctccagttgg tggattatat ggatttatat caataggttc
    15301 tggatgggct tacttagtag gtgcaatatt tggagcttta gtaatagcaa tattatcaac
    15361 aactttagta gacttcaatg aagatgaaac tacggaaaat acagaatttg atgaaataga
    15421 gttagatata atgtaaatta aaaacttaat tttagataat tgagaattga gtgtactctc
    15481 aattctcaat taaattttgg gaggattttt atgaaaaaga caaaagtaca tgtagttcca
    15541 cacagtcatt gggatagaga atggtatttt acaacatcaa ggtcaaaaat atatttaatg
    15601 aaagattttc aagatatatt agacatattg gaagaaaaag aagactttaa atactttact
    15661 atggatgcac aagcttctct cttagatgat tatttaaaat ggagacctca ggatgaatat
    15721 agaataagag atttagttca aagaagaaga ttagttattg gaccttggta tactcaaaca
    15781 gaccaattgg ttatatcagg agaatctata attagaaacc tttactatgg aatagataga
    15841 tgcaatgaat ttggtgaacc tatgagggtt ggatatgtac cagattcttt tgggcaatca
    15901 gctcaaatgc cacaaatata cagaggtttt ggaatagata gttcattatt ttggcgtgga
    15961 gtttctgatg atatggtaga tacaacagag tttatatgga aaggttctga tggttcaaaa
    16021 gtattagcag ttcaaatacc atttggttat tactatggag gtaatatacc agaagatgat
    16081 tctgatttaa aagaatattt aaaagatata atcggaaaac ttaaggttaa agcttctact
    16141 aataacgtat attttccaaa tggatttgac caagcaccaa taagaaaaaa ccttcctgat
    16201 atattaaaaa aagctaatga aatagataat gaaaatgaat acgaaataag tgatatagaa
    16261 aactatatag attcagtaag aaatgaaaga aatgaattta cagagcttaa aggtgaattt
    16321 ttaaatgcta aacatatgag aatacacaaa tccatattct cctcaaggtc agaccttaaa
    16381 ataatgaata acaaattaga aaattatatt acaaatgtac ttgaaccatt attaacatta
    16441 agttattcac ttggaaatga ataccctcac ctagttataa aagatatatg gaaacttatg
    16501 tttgaaaatg cagctcatga cagcataggt tcttgtaata gtgacacaac aaatgaggat
    16561 gtatacacaa gatacaaaca agccagagat ttgagtataa atttattaga tttgcatatg
    16621 agacttataa gtactcaaat caaaaataat aatgaagaaa taacattaac agtattcaat
    16681 ggattcccag aagtcagaaa tgaagttgta gaatttgata cttatattcc aggtcaagat
    16741 tttgtgataa agaataaaaa tggaaaaatt cttaattata taataaaaga aaaagaagat
    16801 attacaaatt atatattaac tcaaacaata agattaaacc caagtaaaaa aatatatata
    16861 cccaaaactg tatatagagc aaaaattgca ctttcagtaa aagatatacc accaatggga
    16921 tatactcaac tagtttttga attggatact aaaaataaat gtgaaataga aacaagtaat
    16981 tgcaaggaaa tagaaaacaa atactacaaa ataacagcca ataaaaatgg ttcattagaa
    17041 atattagata aagaatctaa taagacttat aaaaaccaag ctgtaattga agacaatgga
    17101 gatgatggag attcatacaa ctattctcct ccaagaaaag atatttatgt ttcatcttta
    17161 gattctgtat cttcagtaga agtgctaaaa tcaaacattc aagaagaaat gatacttaaa
    17221 tattcattga ccataccaac ttcactggaa gaaagggcta taggtaaagt ttctgtgaaa
    17281 atgccagtaa caatgaaaat caccttagaa cctaaagaac aaataattaa gtttaatgtt
    17341 aatataaaaa ataaccaagc actatctcat agagtaagag ttttatttaa tacagaaata
    17401 gcatctaagt tttctatagc agatcaacaa tttggaataa tacaaagacc aacagtatta
    17461 gaaaaagacc ttgcattgtg gaaaagagac aattactcat ggcaagaaaa acctataact
    17521 atcgaaccaa tgcaaagttt tgttacttta gaggatggac aaagaggaat agcattaata
    17581 actggttgtg taagagaata tcaaatagtt ggtgataatt tagatacaat agcattaaca
    17641 ctattcaggt catttggata tatgggaaga gaaaatttac tttatagacc aggaagagct
    17701 tctggagaaa aaataatagc aacaccagat gcacaattac ttaaagagtt aaactttgac
    17761 tttggtcttt acatatataa caataaattt gatgaagcaa atgtagctaa tacagctaag
    17821 agattcttaa cacctataca aatatatgaa tatgctgatt ttttaaatgg tagacttata
    17881 tttgcattca atgacgaaaa acaaatatat gaaaatgaat ttagtttgat gaatgtaaat
    17941 aattcaaatt tcacagtaag tgcaataaag aaagaagaaa aaggagatgg aattgtagtt
    18001 agaatcttca atggtatgaa aaatgaggat gctaagggaa gtcttaacat caataaaaat
    18061 gtcaatgatg cttatagtgc aatgctcgac gaaatctatg ataatactag caagcttaaa
    18121 gtaaatacta aaactgtaga ggtaaattct ttatcacatt gtaaagtaca aacaatagta
    18181 attaaataat ataaaatagc ttatacaaga tttcaaaata aattgctagt actatgttaa
    18241 tagtaaagcc agatattatg ctatttataa gctctgtaac actaaataac attttgtaaa
    18301 ataaaaaggt gaaccttgta tattaggatt cacctttttt aaataaatca acattctgtt
    18361 ttaaaataac atttataagc tgttttgaaa taatgcttac aaattatttt aaaacaatac
    18421 ctataaattt ttatttaaag aatacacata aatatttcca gattctttta ttctatagac
    18481 tttataatta ttaaagaagt ctaatctaat ttttgttaaa agtaattgta actttgaata
    18541 aatcaccatc cacacttata ttcatcttac caccctgtaa ttctataaaa ctttttgcta
    18601 tcgctaaacc aagaccagaa ccttctgtgt tacgtgattt atctcctctt acaaatctct
    18661 ccattatatc atctacacta aaatcaatct cagatgcaga catattttta agcataatat
    18721 ttactttatt atctgtttct aaaatatcaa tatacactct tgaatttggc attgcatatt
    18781 tgcttatatt tattataaga ttttcaaata ctctaaatgt acgctgacta tctaatggta
    18841 atattatttt ttcattagaa aagttattct ttactattag agatgaatct gcaagtttgt
    18901 catctaattc taaaagtgtc tgcttcatta gagatacaat atccacattt actatattca
    18961 aataaacatc tccactattt gccttgctta cttcaaacaa atcttctatt agatgttgca
    19021 atctttgtga ctttctgtct aatgtatcaa tatacaactt acgattttca tctgttatac
    19081 tttcatcttt taataaatct atataagtga ttatagatgt tagaggtgtt tttaagtcat
    19141 gtgatacatt tgatataagc tctgttttca tcttttgact cttaacctct tcgtcaacag
    19201 cttttttaaa tccagtttga atatttccta attcatcttt tataggatta aaaaatccta
    19261 aatctttttc catatttaca tctaagtttc catctgaaat tttctttgta acatctaaaa
    19321 gttgattata ttcatatatt gtctttttag agtaatctga cagtatctta aataatacta
    19381 ctgaatatat taatgcgagt attattccaa agaaccacat actacacatt ataactataa
    19441 tcaataaatt tattcccaaa attgtaacta tagttttatt tggcttttct ttcagattta
    19501 ttgttctaat ttgattaata actgcttttc ctgctttttt taaccataca aaaaacattc
    19561 ctgtcacagt atgttttgta aaatactctc ttattccaac atttaaaatg tgttttaaaa
    19621 gtattataaa tacaaatatt attgagaata ttacaaacca ataagttaaa ttcattaaac
    19681 ttaccaatat actagccatt ttagcactta tgtcattgtt tataaggtac tctacataat
    19741 tcccactcaa ggtattactt attataacag taggatataa atctacaagc ccctgtataa
    19801 tagcaagagc aataaagagt atctctaacg gtattcttga taatgtatca aatcctagca
    19861 actctttaga ttttctatat gggaatgcta aagctacaat aacaactata gctaatataa
    19921 tttttaaaat cattccagaa atcttataat aagaattatt ttctacattg cttatatatg
    19981 aaattatacc atcatcaaaa taagtatttc cataaccata ctctacacta tcacctttac
    20041 ttattacttt aggtacagca tatactaatg ttatattttt tattggagat aacttatatg
    20101 aaattgaatt tcctcctaaa cttgtatcca ttaaatcttc tcttgcttta gataacaaca
    20161 tttgattaat aattttttga tttactccat aagaatccac aatatttact tttccatctt
    20221 tatcaaaatt cattacaacg tagaatctat agttttcttt tatatctgta atctgctttt
    20281 gtctttcctc atcattcatt tctgtatttt ttgactgatt ttcattagaa ttttcttttg
    20341 aagcatcatt ttttgttgta tcaagtactc ctaattcttt attatcatta aaaaattcaa
    20401 aattgctttc tttatcaact aaatagtact ttaaattctt tcctgacgct ttaatgaaat
    20461 gctcccaatt ttcaaagttt tcattaaaat ctgcattaat actatcatct gtataataag
    20521 tttctgaacc atcataagta tctttttctt tacttacatt ttttatatag ttcatagttt
    20581 cttcattgat aaatagcttt gatggttgta tcatcttacc ttcttgttct tccttcatat
    20641 tatgatataa aacataactt cctttatata tactatctac aaagctttcc tgttcaaatg
    20701 gattctctgc tccaccttta gcacttgctt gtatagtaga atattgacta atcataccta
    20761 atgatgctga taacataagt ataaaaacta taatagtaac tatatattta tctttaaatt
    20821 ttttcaattt tgtatccaac accccacacc acctttaaat atttaggatt ttttgggtca
    20881 atttctatct tttcccttat attcctcaca tgtaccataa ctgtatctgt atttacagca
    20941 ttctcattcc aaactctttc atatatttca tcagcagaaa aaactcttcc tgcatttctc
    21001 ataagtaaac ttagtatttt aaattctata ggagttgttt ttatatactt tccatcaata
    21061 ctaacttctt ttgtattttc atttaattct aatccgccta ttgcaaacac actatcgtca
    21121 ctttctacct tttgctcttt atttccaacc atgtttagat acttagtgta ccttctaagt
    21181 tgtgaattaa ctctagccaa tagttctaat ggcttaaaag gttttgttac ataatcgtct
    21241 gctcctatat taagccccat tattttgtca acttcttctg attttgcaga tagcattatt
    21301 actggaaaat tatagttttc tctaagcttc attgtaagtg ttataccatc cattttaggc
    21361 atcattatat caactatagc taaatgtatt tcttggtttt ctataacctt aagaccttct
    21421 aatccattgt atcccttaaa aacattatat ccttgattta atagatatat ttctatagca
    21481 tctgctatct ccttttcatc ttctaccacc aaaatattat atgaattcat tctaatctcc
    21541 tttatattaa tttataaatt ttctttacat atatgattat acaatatgat agaagttttt
    21601 ccatttatat atatatttat atcttttgtt ctggttattt gtatttaatg tccatcttag
    21661 aaacctcctt ctagtttaaa tttaatattt tttcattttg ttttatatac ttaatattaa
    21721 aattaaaaac ttaagatatt acatatactt ttctaaa
//
LOCUS       DAJMZY010000070        21721 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.070, whole genome shotgun sequence.
ACCESSION   DAJMZY010000070 DAJMZY010000000
VERSION     DAJMZY010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 21721)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21721)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21721
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.070"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            48..1646
                     /locus_tag="OE968_002483"
     CDS             48..1646
                     /locus_tag="OE968_002483"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative manganese-dependent inorganic
                     diphosphatase"
                     /protein_id="HCP7219759.1"
                     /translation="MSLLVFGHKNPDTDSICSAISLAHLKNKLGIKATAYALGDIRKE
                     AKYALDYFKVDAPEILDNVRIQVRDLNYDKVVPLTPTSSILEAYNLMDEKNVKTLPVT
                     YDDGTFAGIITMKEIAKNLLHQHFTTIHTSLSNICKNLNGTILVDCGEDIKGRVVTLS
                     FGMETLIETLKEGDIAIVGDRYDSIEYAIDTKVKLLILTNHTEISKDLLALAKINGVS
                     VVSVESDNYKTSNVINQCSFLDSIEATENLITFKEDDYMDEIKEIMLETNFRSYPILD
                     DDNKFLGLVSKGHLLNPSKKNVVLVDHNEYAQSADGIEQANIVEIIDHHKLGGISTDV
                     PMSFRVMPVGCNSTIIYQMYKENNVEIPYEIAGLLLSAILSDTLLFKSPTTTDMDKKA
                     CEELSKIAKVDMEKYAMDMFKCGTSLDEYTIEEIVNMDFKEFNMSGHRVGIGQVFTLD
                     IDSIFAKKDEFLSYINSTDYDKLILSVTDIIKEGSYLIYKAEDSLIANAFGVEGVQGT
                     FAPGVVSRKKQLVPNLTTAIKNFK"
     gene            complement(1881..3962)
                     /gene="bclA1"
                     /locus_tag="OE968_002484"
     CDS             complement(1881..3962)
                     /gene="bclA1"
                     /locus_tag="OE968_002484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like exosporium glycoprotein BclA1"
                     /protein_id="HCP7219760.1"
                     /translation="MRNIILYLNDDTFISKKYPDKNFSNLDYCLIGSKCSNSFVKEKL
                     ITFFKVRIPDILKDKSILKAELFIHIDSNKNHIFKEKVDIEIKRISEYYNLRTITWND
                     RVSMENIRGYLPIGISDTSNYICLNITGTIKAWAMNKYPNYGLALSLNYPYQILEFTS
                     SRGCNKPYILVTFEDRIIDNCYPKCECLPIRITGPMGPRGATGSTGPTGVTGPTGSTG
                     ATGSIGPTGPTGNTGATGSIGPTGVTGPTGSTGATGSIGPTGVTGPTGNTGVTGSIGP
                     TGATGPTGVTGEIGPTGVTGPTGVTGSIGPTGATGPTGATGVTGEIGPTGATGPTGNT
                     GVTGATGPTGNTGVTGVTGATGPTGATGVTGEIGPTGATGPTGEIGPTGATGPTGATG
                     VTGEIGPTGVTGPTGEIGPTGATGPTGVTGSIGPTGATGVTGEIGPTGPTGVTGSIGP
                     TGATGPTGNTGVTGVTGPTGATGPTGVTGEIGPTGATGPTGVTGEIGPTGATGPTGPT
                     GNTGATGSIGPTGVTGPTGATGATGVTGPTGPTGATGNSSQPVANFLVNAPSPQTLNN
                     GDAITGWQTIIGNSSSITVDANGTFTVQENGVYYISVSVALQPGSSSINQYSFAILFP
                     ILGGKDLAGLTTEPGGGGVLSGYFAGFLFGGTTFTINNFSSTTVGIRNGQSAGTAATL
                     TIFRIADTVMT"
     gene            complement(4640..5164)
                     /locus_tag="OE968_002485"
     CDS             complement(4640..5164)
                     /locus_tag="OE968_002485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HCP7219761.1"
                     /translation="MENKNPIVTIEMENGKEIKIELYPNIAPNTVKNFVSLVNEGYYN
                     GIIFHRVIPGFMIQGGCPNGTGMGGPGHSIKGEFSGNGFTNNLKHERGVISMARTMAP
                     NSAGSQFFIMHKNSPHLDGQYAGFGRVIEGMDTVDEIASVRTDSADKPQTPQIMKSVT
                     VETFGIDYSDVEKN"
     gene            complement(5229..5981)
                     /locus_tag="OE968_002486"
     CDS             complement(5229..5981)
                     /locus_tag="OE968_002486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HCP7219762.1"
                     /translation="MKLGLCLEGGGAKGAYQAGVVKALYDGGINKFYSISGTSIGAIN
                     GYYLYTGNVDNLEKMWTNIKDIQNGNVKIVNNTVDNSPAIDNLRELDDSNIEEMNFYV
                     NYVEVDNKVVSEKIVDVSKMPRNEAIISISYSGLLPSNPNATLGFKEQFVKDVQEGIY
                     DGFKLDGGLIRSALIEPLIGDNVDKIILISTKYNYELPEDIKKVYDEDKIIVVRPNTQ
                     FAPKDTLNFDDEFCKTIYQEGYEIGKNILDRL"
     gene            complement(6012..7310)
                     /locus_tag="OE968_002487"
     CDS             complement(6012..7310)
                     /locus_tag="OE968_002487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M18 family aminopeptidase"
                     /protein_id="HCP7219763.1"
                     /translation="MDSINFAKNLIDFIYDSPSSFHAVKSTKEILDKNGFEELVLNQR
                     WNLRVGGKYYVTKNLSAIVAFVVNSEDIERDGFRIIGSHSDSPTFSIKPNAEIEAEKS
                     YLKLNTECYGGAILSTWLDRPLGIAGRVVLKGDSILKPNERLIDFKKPICIIPNLAIH
                     LNRSINDGHSYNKQKDMLPLVGMLNDTLEKDNFLIKQIASNLDVNMDDIIDFDLFLYE
                     FEKGSLIGANDEFISIGRQDNLAMVHASLNALVNTKGQHGVNVMAVFDNEEVGSSTKQ
                     GADSNMLLNILERICISMGKDREGFFESIYSSFMISSDLAHAIHPNIPEKHDPTNKPI
                     MGKGPVIKINASQAYTSDGYSIAIYKNICREANVEYQEFVNRSDERGGSTIGPISSTH
                     IDIPSVDVGSPILAMHSIRELGNVEDHYSIYKTFSKFFEI"
     gene            complement(7327..9591)
                     /locus_tag="OE968_002488"
     CDS             complement(7327..9591)
                     /locus_tag="OE968_002488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3553 domain-containing protein"
                     /protein_id="HCP7219764.1"
                     /translation="MNLDTLNPAQREAVEKTEGPVLILAGAGSGKTKVLTTRIAYLIE
                     DKGVQAPNILAITFTNKAANEMRERVEQNIGPETKDMWISTFHSCCVRILRKDINKIG
                     YNRSFVIYDSADQVTLVKDCLKELNLSDKVFEPKAVISAISGAKDKLYTPKQFKDINM
                     ADNRMVKIADIYALYQDRLKRNSALDFDDLILKTVELFKANDEVLAYYRSRFRYIMVD
                     EYQDTSKAQYELIKLLAREHQNICVVGDDDQSIYGWRGADIRNILEFEKDYDNVHVVK
                     LEQNYRSTQVILDAANKVISNNIERKRKKLWSEKKEGELIKIQLTGSEIEEADFIADS
                     IAQIARKENRPYKDFAVLYRANAQARPVEDALNRSQIPYNIYGGTKFYERKEIKDLLA
                     YLRVIQNPQDDISIKRIINVPRRGIGLRTIEKIEDRANLKQESIYSVLIDIETNSDIS
                     TKARASISGFVDIIGTLRTIKEVYPVSKLIEKVLDTTGYMDELVEIRNKNEKDLTGKG
                     EEAQDRIDNLREFISIALEFESSNDDTYENKDLETFLTSIALTSESNDEEDNDRVSLM
                     TIHTSKGLEFPVVFLTGMEEGLFPISRAIKSMSDSQIEEERRLCYVGITRAKEELYMS
                     LTEKRTLYGKTNVAIASRFMEELPEECIERLYKVKKELSYSKASYNMLDKYTKKYMST
                     ISKSKVADKVNATIKDSNKETNPDDIKLGSKVHHPKFGVGTVVSIIGTDVTIAFDQQG
                     IKKINKEYTTLNIL"
     gene            complement(9846..10664)
                     /locus_tag="OE968_002489"
     CDS             complement(9846..10664)
                     /locus_tag="OE968_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HCP7219765.1"
                     /translation="MFKINNLTYQYEKNTNALLNINMDFSKGNVIGIIGSNGSGKSTL
                     FMNLMGILKPTSGEILFKEEKLKYDKRSLYNLRKNVGIVFQDPEKQIFYSKVYDDIAF
                     AMRNIGMDEKTIKERINKALVAVNGIDFIDRPVHFLSYGQKKRVAIASVIAMENEIVL
                     LDEPTAGLDPVSTRSIVDIIKGLNKNNIKIVISSHDMNLMYEICDYIYVLDKGILIDE
                     GKAENVFINENNIIQAGLESPWLVKVHRNMNLPLFKKEEDLYKYWKERELNTNK"
     gene            complement(10657..11355)
                     /gene="cbiQ"
                     /locus_tag="OE968_002490"
     CDS             complement(10657..11355)
                     /gene="cbiQ"
                     /locus_tag="OE968_002490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ECF transporter T component CbiQ"
                     /protein_id="HCP7219766.1"
                     /translation="MLIIDKYAYTNRLSKVNPNKKVAIGVIFLIASMVIQNIFILSGI
                     MILMSILVVCVAGIDLKNYLKLLRIPMYFLFLSIGITLVNISFNKADLLYSFEFFSFN
                     VGISKASIDMSIHVLFRAMSCLTCVYFCILTTPFNQLIFFFKKLHLPDTFVELSMLIY
                     RFIFIFLEEFSEIYKSQELRFGYINLKTSYKSLGILGSMLYKRLMTRYDDMCISLDIK
                     LYDGKFHIVGDNDV"
     gene            complement(11358..11636)
                     /locus_tag="OE968_002491"
     CDS             complement(11358..11636)
                     /locus_tag="OE968_002491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     substrate-binding protein"
                     /protein_id="HCP7219767.1"
                     /translation="MSAKTKTNILLLLLVVALIIFPLLVNSGAEYGGADGQAESEITK
                     INPNYKPWFSSPYEPPSGEIESLLFSAQAALGAGVIGYILGLQKGKRS"
     gene            complement(11626..12378)
                     /locus_tag="OE968_002492"
     CDS             complement(11626..12378)
                     /locus_tag="OE968_002492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006440549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter permease"
                     /protein_id="HCP7219768.1"
                     /translation="MKQNIKLGVIAALMLIILTPVTSNAMHIMEGYLPVKWSIAWGVI
                     FIPFFLFGLKSIGKIVKQDPKKKVLLALCGAFVFVLSALKIPSVTGSCSHPTGVGLGA
                     IMFGPSVMFVLGTIVLIFQALLLAHGGITTLGANAFSMAIIGPIVSFLIFKALKKKDG
                     NNAIPVFLAAAIGDLATYTITSIQLALAFPDPSGGVMASAIKFLGIFFMTQIPIAIAE
                     GILTVIVYNLITENGEKSILENNDKGVKANEC"
     regulatory      complement(12560..12752)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            complement(12884..14656)
                     /locus_tag="OE968_002493"
     CDS             complement(12884..14656)
                     /locus_tag="OE968_002493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitric oxide reductase activation-like protein"
                     /protein_id="HCP7219769.1"
                     /translation="MKWIYDDYEFENRANNLSWTIAGDYNESIDISEKDYSSKEIGLY
                     FAIIAGARRKYVDWDIVKKYLTNRIRKGYNKDIILGLIQVILNTIVEEKVIKDRPGIE
                     DIRRNAYKDIVSRFTKIHNDNIMDKIKYTFVLYSMDKHPALDSMTRRIVNDIRNIDTN
                     QDIMEILKALDVIYLTYFEYILNGEENSLIDENNVESVEVNFDTFADFMYEELYSDEE
                     ENIIESDIDSISSSMLVEGVGDFDDSKCSNSADRVIYVDEDTANKIYSKIEHYYGKTY
                     LSKGEIKKIETQNCRNVHEGCRIHFTDGVLRSECNNVFQLKYVTRQKENNLGKFREHA
                     RMYRQQIKRLKESLSRILIEENAKSRVYSDCGTILANRAWRVGRSNNNKIFYKDIENE
                     KGKYVIDILLDASGSQSRNQGNVAIQAYIIANALTEVGIPNRVMGFSSFLDYTILKRF
                     KDYDDSIKNSENIFEYFCAGNNRDGLAIKSICSGLINRDEENKILIVLSDGRPNDVKI
                     GKSSERTLRGEKAYRGIVGLRDTANEVRKARKQNILVLGVFTGKESELEAERLIYGND
                     FIYSRDITRFSDVVSMYLKKIIRN"
     gene            complement(14670..15599)
                     /locus_tag="OE968_002494"
     CDS             complement(14670..15599)
                     /locus_tag="OE968_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HCP7219770.1"
                     /translation="MDIIDNLRVQGVDEKLIEDVLYFRNYYGLEKDLEYRVTKSKTYF
                     YGKDILSMCIAAILEEENILLSGPKATGKNLLADNLGEIFNRPQWNTSFHINTDSSTL
                     IGTDTFIDNEVKLRRGSVYECAINGGFGVFDEINMAKNDAIVVVHSALDYRRIIDVPG
                     YERVNLHPATRFIGTMNYEYAGTKELNEALVSRFMVIDIPPIEEDKLMMILKNEFSDA
                     DEEKLIHFAGIFLDLQLKSQNGEISSKAIDLRGLMASLKTIRRGLKPTLAINMGLTGK
                     TFDVYEKEMVGDVIKTRIPNKWESIDVFPISHI"
     gene            15828..16016
                     /locus_tag="OE968_002495"
     CDS             15828..16016
                     /locus_tag="OE968_002495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCP7219771.1"
                     /translation="MEYMSCPEVAKKWGISERRVQKLCEESRIPGVSKLGYMWLIPKN
                     AEKPVDGRTKRRKEVQYE"
     gene            16009..16710
                     /locus_tag="OE968_002496"
     CDS             16009..16710
                     /locus_tag="OE968_002496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCP7219772.1"
                     /translation="MNSVLIIDDDKELCALMKKCVEQENLSAITAHGGAEGLHLVDKN
                     RHTLSLVILDIMMPDIDGFQVLKKIRETSNIPVIMLTAKNDEDDKVSGLRLGADDYLT
                     KPFSINELMARVNSLIRRYTMLNPAFITDTDFIIINGMIIDKTNRIVSVNNIPVQLTS
                     KEFDLLAFLASNKGRVFTKKQIYTQVWEEEYAFDDSNIMSFISKLRKKIEPDPNHPFY
                     ILTVRGVGYRFNKEA"
     gene            16712..17635
                     /locus_tag="OE968_002497"
     CDS             16712..17635
                     /locus_tag="OE968_002497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HCP7219773.1"
                     /translation="MNTSVYLLLILALSLIIIAYLVSVLLRVRIQLTLIKDALEDIKN
                     GNLNRRILTDENDITKQICYDINEIAINSQFQLIQQKQSEQAYKQLMTSLSHDVKTPL
                     ASLVGYLEAVESKIVVGEEKDEYIHVASNKAHYLKNFVENLFEWVKLDSKEQVFHFDI
                     FDLNELSRNIISDWIPVLESSHFEYEFDIPEIEYFLRIDANAYTRIINNLLQNIITHS
                     SGNKMTLRIFENKEQAQIIITDNGKGISSDNLPHIFERLYQCDHSRASKGNGLGLAIA
                     KELINAHKGNITANSTPGMGTEFTILLPKAL"
     gene            17792..18715
                     /locus_tag="OE968_002498"
     CDS             17792..18715
                     /locus_tag="OE968_002498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019639192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCP7219774.1"
                     /translation="MNDFVIETKQLTKIYGNQTVVDKVNLHVKKGRIYGLLGRNGAGK
                     TTIMKMILGLTSITYGEVDVFGENIKGREKQVYPRIGAIIETPGFYPNLTGTENLEIF
                     AKLRGTAAPNSVKRALEIVGLPYKNKKLFSKYSLGMKQRLGIANAILHDPELLVLDEP
                     TNGLDPIGIAEMRKFIRDLSVEHGKTILISSHILSEISLLADDIGIIDHGVLLEESSM
                     SELEKKNSKYILLQVSDIPKTSLILERQFNTKDYSVQDDYTLHLYNTNLDMGEINKAL
                     VMQNVTVISSQLCNDTLEDYFKKITGGEGIA"
     gene            18708..19445
                     /locus_tag="OE968_002499"
     CDS             18708..19445
                     /locus_tag="OE968_002499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCP7219775.1"
                     /translation="MLKLIQTEFLKLRRRKLIWLMLLSALIMPFFALLYFNYFGKTGV
                     EPIKFYKWSAFGYTLWIILPVVLGIFCTMLIHEENQYDMLKQLWIVPISKMGYFFSKF
                     FVVLIYSICFMLITAVASVLFSVLSGYVVFSWASILYLLKKCLEIGVITAFVMLPILA
                     IATSQKGYILPICITLVYAFSGFVIMTINMYLHPLSSMGVIIMRNKDIPGLIFSQEIN
                     VPLAFLCICIWSIVSVLFANIALGRRK"
     gene            19456..20229
                     /locus_tag="OE968_002500"
     CDS             19456..20229
                     /locus_tag="OE968_002500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCP7219776.1"
                     /translation="MWKLLWAECQKIRRSKIVWITVFASIMIAVIVFAGGQDVYNDPD
                     LHYGLKSVYDGSRYIDNAGWYMDAVQPWSTFFVLPAVIALLGSYIICREEEEDTIKSL
                     RLIPINETNLTIAKMIITFIFSILLYLLLFTITFLTESVLHFSDLSTKLVLSCMKEYF
                     LDGIGVFFAISPIIALVSRMKKGYWLALVFTEVYSIAGLFAGMSNVLQTFFPIAAIFN
                     ISGYYITTGEKIMGSIMSLLLCACLSAFILKGLKHNEKN"
     gene            complement(20770..21378)
                     /locus_tag="OE968_002501"
     CDS             complement(20770..21378)
                     /locus_tag="OE968_002501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HCP7219777.1"
                     /translation="MSVINSFILQYGLISVFVLIMIEYACFPLPSEVVLPLCGAIAAR
                     NHFGFLTILILSIIAGILGSIFCYTVGNWGGKSIINKIIEICPKAKKGIFASQDYFNK
                     YSSISVCVCRLIPLCRTYISFIAGIAGQNIITFVISSIVGITIWNTSLISIGYIFSES
                     WVRIMSHYNDYKFLVLIIPISIIFIGFVIKSFIHKKHHKIRL"
     gene            complement(21556..21672)
                     /gene="rrf"
                     /locus_tag="OE968_002502"
     rRNA            complement(21556..21672)
                     /gene="rrf"
                     /locus_tag="OE968_002502"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         6897 a         3781 c         2861 g         8182 t
ORIGIN      
        1 atttttatca attattatta tattcaagtt ttgaaaggag tattaaaatg agtttattag
       61 ttttcggaca taaaaatcca gatacagatt caatatgttc tgcaatttca ttagcacatt
      121 taaagaacaa actaggaata aaagcaacag cttatgcttt aggagatatc agaaaagaag
      181 ctaaatatgc cttggattac tttaaggtag atgcacctga aattttagat aatgttagaa
      241 tacaagttag agatttaaat tatgataaag tagtaccttt aacaccaact tcatctatat
      301 tagaggctta taaccttatg gatgaaaaaa atgttaaaac actacctgta acttatgatg
      361 atggaacttt tgctggtatc attactatga aagaaatagc taaaaatcta cttcatcaac
      421 actttacaac tatacacaca tcactatcaa acatttgtaa aaaccttaat ggtactattc
      481 ttgtggactg tggtgaagat ataaaaggta gagtagtcac tttatcattt ggaatggaga
      541 ctctaataga gactttaaaa gaaggagaca tagctattgt tggagataga tatgatagta
      601 ttgaatatgc tattgataca aaagttaaac ttttaatact tactaatcat acagagattt
      661 caaaagattt gctagctctt gctaagataa atggagtgtc tgttgtttct gttgaaagtg
      721 acaattataa aacttctaat gtaataaatc aatgtagttt cttagactct atagaagcta
      781 cagaaaattt aattacattc aaagaagatg attatatgga tgaaataaaa gagattatgc
      841 tagaaacaaa cttcagatct tatccaatat tagatgatga taataagttt ttaggtttag
      901 tttcaaaagg tcatctatta aacccatcta aaaagaatgt tgttttagtt gaccataacg
      961 aatatgctca aagtgctgat ggaattgaac aagcaaacat agttgaaata attgaccatc
     1021 ataaacttgg cggtatttct actgatgttc ctatgtcatt tagagttatg cctgttggat
     1081 gcaatagtac tataatttat caaatgtaca aagaaaataa tgttgagata ccttatgaaa
     1141 tagctgggct tcttttatct gctatattat cagatacatt attatttaag tctccaacaa
     1201 caactgatat ggataagaaa gcttgtgaag aattaagtaa aatagcaaaa gtagacatgg
     1261 aaaaatacgc tatggatatg tttaaatgcg gtacttcttt agatgaatat actatagaag
     1321 aaatagtaaa tatggacttt aaagaattta atatgagtgg acatagagtt ggtattggac
     1381 aagtatttac cttagacata gactctatat ttgctaaaaa agatgagttt ttatcttata
     1441 taaattcgac tgattatgat aaattaattc tttcagttac agatataatc aaagaaggtt
     1501 cttatttaat ctataaagca gaagatagct taattgctaa cgcatttggt gttgaaggtg
     1561 ttcaaggcac atttgcacca ggtgttgtat caagaaaaaa acaattagtc cctaatttaa
     1621 ctactgcaat caaaaatttt aaataatata aaatttttaa ataacgaaaa ctgtctcaaa
     1681 tctatatttg agacagtttt ttattatata tatattgata ataaagttaa ataaaaatcc
     1741 ataaatttaa aatttttatg aatatatttt attattattg ttattttatt cattctaaaa
     1801 taggtaaaac tcaatatata aaaatacttt tgtcatttaa ataaaaccta aatagttttt
     1861 aagattattt tagacacgtt ttaagtcata acagtatcag ctattctaaa tatcgtcaaa
     1921 gtagccgcag ttcctgctga ttgcccattt cgtatcccta ctgttgtaga tgaaaagtta
     1981 tttattgtaa aagtagtccc accaaataaa aaaccagcaa aatatccaga aagtactcct
     2041 ccgcctcctg gctcagtagt aagccctgcc aaatcttttc ctcctaaaat tgggaatagg
     2101 atagcgaaag aatattgatt tatacttgat gaacctggtt gtaatgctac tgaaactgat
     2161 atataataca caccattttc ttgtactgta aacgtaccat ttgcatctac tgttatactt
     2221 gaactatttc ctattattgt ttgccaacct gttatagcat ctccattatt tagtgtttgt
     2281 ggagatggtg catttacgag gaagttagca actggctgag aggaattgcc tgttgctcct
     2341 gttggacctg ttgggcctgt tactcctgtc gctcctgttg ctcctgttgg acctgttact
     2401 cccgttggcc ctatacttcc tgtcgctcct gtatttcctg ttgggcctgt tggtcctgtt
     2461 gctcccgttg gtcctatttc tcctgttact cctgttgggc ctgttgctcc cgttggtcct
     2521 atttctcctg tcactcctgt tgggcctgtt gctcccgttg ggcctgttac tcctgtcact
     2581 cctgtatttc ctgtcggtcc tgttgctccc gttggtccta tacttcctgt cactcctgtt
     2641 gggcctgttg gtcctatttc tcctgtcact cctgtcgctc ctgttggtcc tatacttcct
     2701 gtcactcctg ttggtcctgt tgctcctgtt ggtcctattt ctcctgttgg gcctgttact
     2761 cctgttggcc ctatttctcc tgtcactcct gtcgctcctg ttgggcctgt tgctcccgtt
     2821 ggtcctattt ctcctgttgg gcctgttgct cctgttggcc ctatttctcc tgtcactcct
     2881 gtcgctcctg ttggacctgt tgctcctgtt actcctgtta ctcctgtatt tcctgttgga
     2941 cctgttgctc ctgttactcc tgtatttcct gttggacctg ttgctcccgt tggtcctatt
     3001 tctcctgtca ctcctgtcgc tcctgttgga cctgttgctc ctgttggtcc tatacttcct
     3061 gtcactcctg ttgggcctgt tactcccgtt gggcctattt ctcctgtcac tcctgttggg
     3121 cctgttgctc ccgttgggcc tatacttcct gtcactcccg tatttcctgt cggacctgtt
     3181 actcctgttg gtcctatact tcctgtcgct cctgtacttc cggttgggcc tgttactccc
     3241 gttggcccta tacttcctgt tgctcctgta tttccggttg ggcctgttgg tcctatgctt
     3301 cctgtcgctc ctgtacttcc ggttgggcct gttactcctg ttgggcctgt acttcctgtc
     3361 gctcctcttg gtcccattgg acctgtaatt ctaattggaa gacactcaca tttaggataa
     3421 caattatcta taattctatc ttcaaatgtt acaagtatat acggtttgtt acaacctcta
     3481 ctagatgtaa attcaagaat ctgataaggg taatttaaag ataaagctaa cccataatta
     3541 ggatatttat tcattgccca tgcttttata gttcccgtaa tatttaaaca aatatagttg
     3601 gatgtatcac ttatcccaat tggtaaatat cccctgatat tttccataga cactctatca
     3661 ttccatgtta tagttcgtaa attataatat tcacttattc ttttaatttc aatatctact
     3721 ttttctttaa aaatatgatt cttatttgaa tcaatatgaa taaataactc tgcttttaat
     3781 atacttttgt cttttaatat atctggtatt ctcactttaa aaaaagtaat caacttttct
     3841 tttacaaaac tatttgaaca tttacttcct attaagcaat aatctaaatt actaaagttt
     3901 ttatctggat attttttaga tataaaagta tcatcattta aataaagtat aatatttctc
     3961 atttataatc cctccatttt gggtctatat catactatgt ttaaaataca tgcttagtta
     4021 caatacaatt aaaatttata gtattaaatt tttatataat aatgctgatt tctacaaaaa
     4081 aagaacatgt cattagaaat ttctaatagc atgttctttt tcattattat atattacact
     4141 ttaaattatt ccttgactgg cttagctggt gtaaactaaa ccagtctttc taaaatatta
     4201 agcacttttt tcttattatg ttttttagga tttattgtct atattattgt aaaccaaagt
     4261 tataaaattg taaatagaat atattaccat aacaatattt ttttataagt aaaaattata
     4321 aaaaacttta tttttgttaa atggaataaa taaaataagt ttaaaaaata ctgaaataag
     4381 tgttttccac atattttata tatttattta atacattatt atttaaaaat aaatatataa
     4441 acaatcataa taaaattttt ttaataaaac tttatttttt agttaaaatc atacaatata
     4501 tagatttcca caatacaaat aaattaaaaa gtgaaatgta tttgtctaaa aacataataa
     4561 catttcactt tatcctcatt tttaagtaat atatattttt aatttttatt tataactaaa
     4621 tctagttttt atataaattt tagttttttt ctacatctga gtaatctatt ccaaaagttt
     4681 ctacagtaac agatttcata atttgtggag tttgtggctt atcagctgaa tctgttctaa
     4741 ctgatgctat ttcatcaact gtatccatac cttctatcac tctaccaaaa cctgcatact
     4801 gaccatctaa gtgtggtgag tttttatgca ttatgaaaaa ttgagaacca gctgaattag
     4861 gtgccatagt tctagccatt gatatgactc ctctttcatg ttttaaattg ttagtaaatc
     4921 cattaccact aaattcacct tttattgagt gacctggacc acccattcct gtaccatttg
     4981 ggcatcctcc ttgtatcata aatcctggta ttactctatg aaatattatt ccattgtaat
     5041 atccttcatt tactaatgat acaaagtttt taactgtatt tggagctata tttggatata
     5101 actcaatttt gatttctttt ccattttcca tttctatagt tactatagga tttttatttt
     5161 ccataattta ttaccttcct tttcattagt taaattacat aattacattt attatattat
     5221 actctaaatt aaagtctatc aagtatattt tttcctattt catatccttc ttgataaata
     5281 gttttacaaa actcatcatc aaagttaagc gtgtctttag gagcaaattg agtattaggt
     5341 ctaactacta ttattttatc ttcatcatat acttttttaa tatcttctgg caactcataa
     5401 ttatattttg tggatattaa aataatttta tccacattat ccccaattaa tggttcaatt
     5461 aatgcactcc taattaaacc tccatctaat ttgaaaccat cataaattcc ttcttgcaca
     5521 tctttcacaa attgttcttt aaatccaaga gttgcgtttg gatttgatgg taacaaccca
     5581 ctgtatgaaa tgctgataat ggcttcatta cgaggcattt ttgatacatc aacaatcttt
     5641 tctgatacta ctttattatc aacttcaaca taattaacat aaaagttcat ttcttctata
     5701 ttactatcat ctagttccct taggttgtct atagcaggag aattatccac agtattattt
     5761 actattttta catttccatt ctggatatct tttatatttg tccacatttt ctccaagtta
     5821 tcaacattcc ctgtgtacaa ataatatcca tttattgctc ctattgatgt ccctgaaatc
     5881 gaataaaatt tatttattcc tccatcatac aaggctttaa ctactcctgc ttgataagcc
     5941 ccttttgctc ctccaccttc taaacataat cctaatttca tagtctcatc tccaaattgt
     6001 ttatcttata tttatatttc aaaaaactta ctaaatgttt tatatatact atagtggtcc
     6061 tcaacatttc ctaattctct tatagaatgc attgctaaaa ttggacttcc cacatccaca
     6121 gatggtatat ctatatgagt agaagatatt ggacctatag tacttcctcc tctttcatct
     6181 gacctattaa caaattcttg atactcaaca ttagcttctc tacatatatt tttataaata
     6241 gctatagaat atccatcact agtatacgcc tgactagcat ttatctttat aaccggacct
     6301 tttcccatta ttggtttatt agttgggtca tgcttttctg gaatgtttgg atgaatagca
     6361 tgagctaaat ctgatgatat cataaaagat gaataaatag actcaaagaa tccctctcta
     6421 tccttaccca ttgatataca aattctctcc aatatattta acaacatgtt tgaatctgca
     6481 ccttgtttag tagagctacc aacttcttca ttgtcaaata cagccattac atttacacca
     6541 tgttgacctt tagtattaac aagagcattc aaactagcat gtaccattgc aagattatct
     6601 tgtctcccaa tagatataaa ttcatcatta gcccctatta aacttccttt ttcaaattca
     6661 tataaaaata aatcaaaatc tataatatcg tccatattta catctaagtt agatgctatt
     6721 tgctttataa gaaaattatc tttttctaat gtatcattta acatcccaac taaaggtaac
     6781 atatcttttt gcttattata tgaatgacca tcatttatac ttctatttaa atgtattgct
     6841 agatttggta ttatacaaat tggcttttta aagtctataa gcctttcatt tggttttaat
     6901 atactatcac cttttaaaac tactctacca gctatcccaa gaggtctatc caaccatgta
     6961 cttaatattg ctcctccata gcattctgta tttaacttca aataagattt ttcagcttct
     7021 atttctgcat ttggtttaat actaaatgta ggagaatctg aatgagagcc tattattcta
     7081 aatccatctc tttctatatc ttctgaattt actacaaaag ctactatagc tgataaattc
     7141 ttagtaacat aatactttcc accaactctt agattccatc tttgattcaa aactaattct
     7201 tcaaatccat ttttatctaa gatttcctta gtactcttga ctgcatgaaa agacgacgga
     7261 ctatcatata tgaagtctat taagttttta gcaaagttta tactatccat tcctcattta
     7321 cctccattat aaaatattta gtgttgtata ttctttattt atttttttaa ttccctgttg
     7381 gtcaaaagct atagtaacat ctgtaccaat tatagaaacc actgtcccaa ccccaaattt
     7441 aggatgatgt accttagaac caagttttat atcatctgga ttagtttctt tattagaatc
     7501 ttttattgta gcattaactt tatctgcaac tttagatttg cttatagtac tcatatactt
     7561 tttagtatat ttatctaaca tattataact tgctttagaa tagcttagtt ctttttttac
     7621 tttgtacaat ctttctatac attcttctgg cagttcttcc ataaatcttg aagctattgc
     7681 aacatttgtt ttaccatata atgttctctt ctctgtcaat gacatatata gctcttcttt
     7741 agctctagtt ataccaacat aacaaagtct tctctcttct tctatttgtg aatcactcat
     7801 agattttata gctcttgata taggaaataa cccttcttcc atacctgtta aaaacacaac
     7861 agggaactct aaacctttag atgtatgaat tgtcataagc gaaaccctat cattgtcttc
     7921 ttcatcattt gattcagatg taagtgctat acttgttagg aatgtctcta agtctttatt
     7981 ttcataagta tcatcattac tactttcaaa ctccaaagct atagaaataa attctctcaa
     8041 attatcaatt ctgtcttgag cttcttcacc tttgcctgtt aaatcttttt catttttatt
     8101 tcttatctct acaagctcgt ccatatatcc tgtagtgtcc aagacttttt ctataagttt
     8161 gctaacagga taaacttctt ttatagttct aagagtccct ataatatcaa caaatccact
     8221 tatacttgcc cttgccttag tagatatatc tgaatttgtt tctatatcaa ttaatactga
     8281 gtatatactt tcctgtttta agttagctct atcttcaatt ttttctatgg ttctaagccc
     8341 tatacctctt ctaggaacat ttataatcct ttttatagat atatcatctt gtggattttg
     8401 aataactctt aaatacgcca acaaatcctt tatttctttt ctctcataga attttgtacc
     8461 accatatata ttgtatggaa tttgacttct atttaaagcg tcctctacag gtcttgcctg
     8521 tgcatttgct ctataaagta ctgcaaaatc cttataaggt ctattttctt ttctagctat
     8581 ttgtgcaatt gaatcagcaa tgaaatcagc ctcttctatt tcactaccag ttaattgtat
     8641 ctttataagt tctccttctt ttttttcact ccaaagcttt tttctttttc tttctatatt
     8701 attagatata actttattag ctgcatctaa tatcacttgt gtagacctat aattttgttc
     8761 caactttaca acatgtacat tgtcataatc tttctcaaat tcaagtatgt ttcttatatc
     8821 tgcacctctc catccataaa tactttggtc atcatctcca acaacacaaa tattttgatg
     8881 ttctcttgct aataatttta tcaattcata ttgagcttta cttgtatctt ggtactcatc
     8941 taccattatg tatctaaatc tacttctgta atatgctaac acttcatcat tagccttgaa
     9001 aagttctaca gttttaagta ttaaatcatc aaagtcaagt gcactatttc tttttaaacg
     9061 gtcttgatat agcgcataaa tatctgcaat cttaaccatt ctattatctg ccatattgat
     9121 atctttaaac tgctttggag tataaagttt atcttttgct cctgaaattg cacttataac
     9181 tgcttttggt tcaaacactt tatcacttaa atttaattct tttagacagt ctttaaccaa
     9241 tgtaacttgg tctgctgaat cataaattac aaaacttcta ttgtaaccaa tcttatttat
     9301 atcttttctt agtatacgaa cacagcaaga atggaatgta cttatccaca tatccttagt
     9361 ttcaggacct atattttgtt caactctctc tctcatttca tttgcagctt tgtttgtaaa
     9421 tgttatagct aatatatttg gtgcttgtac acctttatct tctataagat atgctattct
     9481 tgttgttaat accttagttt tacctgaacc agcaccagcc agtataagta ctggaccttc
     9541 agtcttttct actgcttctc tttgagcagg atttaatgta tctaaattca tatttctcct
     9601 cctgttaaca gccataaata tattttaatc taaaatatga attacttcaa attataatta
     9661 tgtattatat taatagatta tttccaatat attacaatta aataacattt ttccatataa
     9721 tttatttcat tgtttaataa aaaaaataac cttatgattt ggggaatcat aaggcacctt
     9781 taaggggtct aggttaaggg ttattatata taaatctatt tttttaaaat aggtttaggg
     9841 cttaattatt tatttgtatt aagttctctt tccttccaat acttatacaa atcttcttct
     9901 ttcttaaata agggtaaatt catatttcta tgtactttta ctaaccatgg ggattctagg
     9961 ccagcttgta taatattatt ttcatttata aacacatttt ctgcttttcc ttcatcaatc
    10021 aaaatcccct tatccaatac atatatgtaa tcacatattt catacattaa attcatatca
    10081 tgactggata ttactatttt tatattattt ttatttaatc cctttattat atctacaata
    10141 gacctagtac ttactgggtc taaaccagct gtaggttcat caagtaatac aatttcattt
    10201 tccattgcta taactgatgc tattgccact ctttttttct gtccatagct aagaaaatgt
    10261 actggcctgt ctataaaatc tattccatta acagctacta gagctttgtt tattctctct
    10321 ttaattgttt tttcatccat accaatgttt ctcattgcaa aggctatatc atcatatact
    10381 tttgaataaa aaatttgttt ttctgggtct tggaacacaa tacctacatt ttttctaagg
    10441 ttgtataaac ttctcttatc atattttaac ttttcttctt taaaaagaat ttctccagat
    10501 gtaggcttta atatacccat taaattcata aataatgttg attttcctga accatttgaa
    10561 cctattatac ctataacatt tccctttgaa aaatccatat taatgtttaa tagtgcattg
    10621 gtattttttt catattgata cgttaaatta tttattttaa acatcattat cccctactat
    10681 gtgaaattta ccatcataca attttatgtc taatgatata cacatatcat cataccttgt
    10741 cataagtctt ttgtacagca tacttccaag aatacctaag gatttatatg aagtttttaa
    10801 atttatatat ccaaatctta gctcttgtga cttgtatatt tctgaaaatt cttctaaaaa
    10861 tatgaatata aacctatata ttaacattga taactcgaca aaagtgtcag gtaaatgaag
    10921 ttttttaaaa aagaatatta attgattaaa aggtgttgta agtatacaaa aatacacaca
    10981 agtcaaacaa gacatcgctc taaataacac atgaatagac atgtcaatag acgcctttga
    11041 tattcctaca ttaaaactaa aaaattcaaa actatataat aaatctgctt tattaaaaga
    11101 tatatttaca agagttattc ctatactaag aaataaaaag tacattggta ttctaagtaa
    11161 ttttaaataa ttttttaaat ctattccagc cacacaaaca accaaaatac tcattaaaat
    11221 cataattcca cttaaaataa atatattttg tattaccata gaagcaatca gaaaaattac
    11281 tcctatggct acttttttgt ttggatttac tttactcaat ctatttgtat atgcatattt
    11341 atcaattata agcatgatta acttctcttt cctttttgaa gacctaatat gtatcctatt
    11401 acaccagccc ctaaagctgc ttgtgcagag aataataaac tttctatttc tccacttggt
    11461 ggctcatatg gactgctaaa ccatggtttg taatttggat ttatcttagt aatttcactt
    11521 tcagcttgac catctgctcc tccatattca gcacctgagt tgacaagtaa tgggaatata
    11581 ataagagcta ctactaataa aagtaataat atgttagttt ttgttttagc actcattagc
    11641 tttaactcct ttatcattat tttctagtat gcttttttct ccgttttctg taattaaatt
    11701 atatacaatt acagtaagta taccttctgc tattgctatt ggtatttgag tcataaagaa
    11761 aattcctaaa aatttaattg ctgaagccat taccccacct gatgggtctg ggaaagccag
    11821 tgctaattgt attgaagtta ttgtatatgt ggctaagtct cctattgctg ctgcaagaaa
    11881 tactggaata gcattatttc catctttttt ctttaaagcc ttaaatatta ggaatgatac
    11941 gattggccct attatcgcca ttgaaaaagc attagctcct aaagtagtta ttcctccatg
    12001 tgctaataac aatgcttgga atattaaaac tatagttcca agaacaaaca ttacgcttgg
    12061 tccaaacatt attgctccaa gacctacacc agtaggatgt gaacaacttc ctgttactga
    12121 aggtattttt agtgctgata atacaaacac aaatgctcca cataaagcta ataatacttt
    12181 ctttttaggg tcttgcttta ctattttacc tattgatttt aatccgaata agaaaaatgg
    12241 tataaatata actccccatg ctatagacca ttttactggt aagtaacctt ccattatatg
    12301 cattgcattt gatgtaactg gagttaaaat gattaacata agtgcagcta taacccctaa
    12361 tttaatattc tgtttcatct tagtatccct ctctcccttt ctaataatta aaacataata
    12421 atacatgtct gatttattta ataaaataaa aaagcctaac tcgatggtta ggcttctaat
    12481 tttccacaat ctaaatacaa acacataaaa caaacatatc tgtataatta ttataagaaa
    12541 ctttctccat ccccgaagaa attactttaa tattttaggc aggtctcctg acttagcttc
    12601 atcctactcc tcttccttcc catgagatat aaaaaatatc atcatagtgg ctaacaaaag
    12661 tttcgtctgc atcacagtag cgggggctgt aaaggaattt aacctttttc cctattaatc
    12721 ttgcttaaag aacctataat attatatatt taatttttaa attcttctta aattattttc
    12781 tatataaatc attgtatacc ttttctgtga aaatttctac attttttata aattttattc
    12841 atttttatat ttttatgtat ataaattctt ttttgtaagt ttattaattt ctaattatct
    12901 tctttaaata cattgaaact acatcagaaa atctagttat atctcttgaa tatataaaat
    12961 catttccata tattaatctt tcagcttcaa gttctgattc ttttcctgta aatactccta
    13021 atactaatat attttgcttt ctagcttttc tcacttcatt ggctgtatct ctcaaaccaa
    13081 ctatacccct ataagccttt tctcctctta atgttctctc actacttttt cctatcttta
    13141 catcatttgg tcttccatca ctgagaacta tcaggatttt attttcttca tctctattta
    13201 ttagaccact acatatagat tttattgcca aaccatctct attattacca gcacaaaaat
    13261 attcaaatat attttcacta ttttttatac tatcatcata atctttaaat ctttttaata
    13321 ttgtatagtc taaaaaacta gaaaatccca tcactctatt tggtatgcca acttctgtta
    13381 gagcatttgc aattatgtaa gcttgaattg ccacatttcc ctgatttcta ctttgagagc
    13441 cacttgcatc caataatata tcaataacgt atttcccttt ttcattttct atatctttat
    13501 aaaatatttt attattatta cttctaccaa ctctccaagc tctattggct aatatagtac
    13561 cacaatcaga atatactcta cttttagcat tttcttctat taaaattctt gatagacttt
    13621 cttttaatct ctttatttgc tgtctataca ttctagcatg ttctctaaat tttcctaaat
    13681 tattttcttt ttgtcttgtt acatatttta gttgaaatac attattacac tcacttctaa
    13741 gaactccatc tgtaaagtgt attctacaac cttcatgaac atttctacaa ttttgtgtct
    13801 caattttttt aatttcacct ttactcaaat aagtttttcc ataataatgt tctatttttg
    13861 aatatatctt atttgcagtg tcttcatcaa catatataac tcggtctgct gaattgctac
    13921 atttagaatc atcaaaatcc cctacacctt ctacaagcat ggatgaagat attgaatcta
    13981 tatcactttc aataatattt tcttcttcat cactataaag ttcttcatac atgaaatcag
    14041 caaatgtatc aaaatttact tctacacttt ctacattatt ttcatcaata agactatttt
    14101 cttctccatt taatatgtat tcaaaataag ttaaatatat aacatctaat gcttttaaaa
    14161 tctccataat atcttgattg gtatctatat ttcttatatc attaactatt cttctagtca
    14221 tactatctaa tgctgggtgc ttgtccatac tataaagtac aaatgtgtat ttaattttat
    14281 ccataatatt atcattgtgt attttggtaa aacgtgaaac aatatcttta taagcatttc
    14341 ttcttatgtc ttctatccct ggcctatctt taatgacctt ttcttcaact attgtattta
    14401 atataacttg aattagaccc agtataatat ctttgttgta tccttttctt attctatttg
    14461 taagatattt tttaactata tcccaatcta catactttct tctagcacct gcaattattg
    14521 caaaatatag acctatttct tttgaagagt aatctttttc tgatatatct atactttcat
    14581 tgtaatcacc agctattgtc catgataagt tattagctct attttcaaat tcataatcat
    14641 catatatcca tttcataatc tcacctatat taaatatgac ttattggaaa cacatctata
    14701 ctctcccatt tattaggtat tctagtttta attacatctc caaccatttc tttctcatat
    14761 acatcaaaag tctttcctgt aagtcccata ttaattgcaa gagttggttt taatcctctt
    14821 cttatagtct taagagatgc cataagacca cgtaaatcaa tagctttact agatatctct
    14881 ccattttgag acttcaattg taaatctaaa aatattcctg caaagtgtat tagtttttct
    14941 tcatcagcat ctgaaaattc attttttaaa atcatcatta acttatcttc ttctatagga
    15001 ggaatatcta ttaccataaa tctagatacc agtgcttcat taagttcttt tgttcctgca
    15061 tattcataat tcatagtccc aataaatctt gttgctggat gtagattgac tctctcatac
    15121 ccaggtacat caattattct tctatagtct aaagctgaat gtaccacaac tatagcatca
    15181 ttttttgcca tattaatttc atcaaacacc ccaaaacctc cattaatagc acactcataa
    15241 actgagcctc ttctaagttt aacttcattg tctataaatg tatctgtacc tataagtgtt
    15301 gaactgtctg tatttatatg aaatgatgta ttccactgag gtctattaaa tatttcccct
    15361 agattatcag caagtaagtt ttttcccgtt gcctttggtc ccgataataa tatattttct
    15421 tcttctaaaa tagctgctat acacatagac aagatatctt taccataaaa ataagtttta
    15481 gactttgtta ctctgtattc taaatctttt tctaatccat aataatttct aaaatacagt
    15541 acatcttcaa taagtttttc atctacccct tgcaccctta gattatctat tatatccata
    15601 tttttacccc ttttatataa atagtatttg tttcatttct tatcaccatt ttagcataaa
    15661 aggatataag ctaaaattga ttttttaatc tcccccattt taagtaaaac catgcaccat
    15721 tttatcacta caaaattaag agtactactt actgatattt cttgatttta ttcgtctata
    15781 cgtatataat atatactgat aaattatgag gaaaggatga ttgaaatatg gaatatatgt
    15841 cttgcccaga agtagcaaaa aaatggggta tttctgaaag aagagtacaa aaactatgtg
    15901 aagaaagtcg cataccagga gtttcaaaac tcgggtatat gtggctgata ccaaagaacg
    15961 cagaaaagcc tgttgatggt agaacaaaaa gaagaaagga agtacaatat gaatagcgtt
    16021 ttgattatag atgatgacaa agaactttgt gctcttatga aaaaatgtgt tgagcaagaa
    16081 aatttatctg ctattactgc acatggtggt gcagaaggtc tacatttagt cgataaaaat
    16141 agacacacac tctctcttgt aattttggac ataatgatgc cagatataga cggttttcaa
    16201 gttctgaaaa aaattagaga aacaagtaat attccagtaa ttatgcttac tgctaaaaat
    16261 gacgaggatg ataaagtttc cggactacgt ttaggtgctg acgattacct aacaaaaccg
    16321 ttcagcataa acgaacttat ggctcgtgtc aattctctta ttcgtcggta tactatgcta
    16381 aaccctgctt ttataacaga cacagatttc ataataataa atggcatgat tattgacaag
    16441 acaaaccgaa ttgtttctgt caataatatt cctgttcaac ttacaagcaa agaatttgat
    16501 ttacttgctt ttctggcttc taataaggga cgggtgttta ccaaaaaaca gatttataca
    16561 caagtatggg aagaagaata tgcttttgac gatagtaaca tcatgtcttt catcagtaaa
    16621 ttgagaaaaa agattgaacc agaccccaac catccatttt atattttgac agttcgtggt
    16681 gtcggttatc gttttaataa ggaggcttaa catgaataca agtgtctatc tgcttttgat
    16741 attggctctt agcctgatta ttatagcgta ccttgtttct gtcctgctac gtgtccgaat
    16801 acaacttaca cttataaaag atgctttaga ggatataaaa aatggaaacc ttaatcgacg
    16861 tattttaaca gatgaaaacg acattacaaa acaaatttgc tatgatatta acgaaatagc
    16921 aatcaatagc caatttcaac ttattcagca aaaacaatca gaacaagcct acaaacagct
    16981 aatgacaagt ctctcccatg atgtaaaaac tccacttgct tctttggtcg gttatttgga
    17041 agcagtagaa agtaaaattg ttgtaggaga ggaaaaagac gagtatatcc atgttgcgtc
    17101 taataaggct cattacttaa agaattttgt agaaaatcta tttgaatggg taaaattgga
    17161 ttctaaggaa caagtttttc attttgatat ttttgacttg aatgaattat cccgtaatat
    17221 tatatctgat tggatacctg ttttagaaag cagtcatttt gaatatgaat ttgatatacc
    17281 agaaatagag tacttcttac gtatagacgc aaatgcatat acccgtatca ttaataacct
    17341 attacaaaat attattaccc atagtagtgg aaacaaaatg acattgagaa tttttgaaaa
    17401 caaagagcaa gctcaaatta taataacaga taatgggaaa ggtatatctt cagacaatct
    17461 cccacatatt tttgaaaggt tgtaccaatg cgaccattca cgagcttcaa agggaaatgg
    17521 tttaggcttg gcgattgcaa aggaacttat taacgctcat aagggaaata ttaccgccaa
    17581 cagcactccc ggtatgggaa cagaatttac aatattgctt cctaaagccc tgtaaaagta
    17641 cgaggctttc ttactctaaa acaagataaa agcaagatta tggcaaggtt ttggcaaggt
    17701 tcatgtttta taattctaat tgtagttgat tttgacgttg tatcaactat cttttgtaga
    17761 aacaaattta ttaaaagtga ggaaattata tatgaatgat tttgtgattg aaacaaagca
    17821 acttacaaaa atttatggga atcaaacagt agttgacaaa gtcaatctcc atgtaaaaaa
    17881 aggccgaata tatggtctgt taggacgcaa cggagctggg aaaaccacaa ttatgaaaat
    17941 gattttagga ttgacttcaa tcacgtatgg cgaggtagat gtatttggag agaatattaa
    18001 gggacgtgaa aaacaagtat atccccgtat cggtgcaatt atcgaaacgc caggatttta
    18061 tcctaatctg acaggaacgg agaacttgga gatttttgca aaactgcgtg gtacagccgc
    18121 ccctaattct gtaaaaagag cattggaaat tgtaggctta ccttataaaa ataaaaagct
    18181 gtttagtaaa tattcacttg gcatgaaaca gcgacttggt attgccaacg ctatcctgca
    18241 tgacccagaa ctgttagttt tagatgagcc aaccaatggt cttgacccta ttggtattgc
    18301 ggagatgaga aagtttatta gggacttgag cgttgagcat ggaaagacaa ttcttatttc
    18361 cagtcatatt ctttcagaaa tctcattgtt ggctgatgat attggaatta tcgaccacgg
    18421 tgttcttttg gaagaaagta gtatgagtga actagaaaag aaaaacagta aatatatcct
    18481 gctacaagtt tcagatattc cgaagacatc acttatttta gagcgtcaat ttaacacgaa
    18541 ggattattcc gttcaagatg actacacgtt acacctttat aacactaatc tggatatggg
    18601 tgaaatcaat aaagcacttg taatgcagaa tgtaactgtt attagttctc aactttgtaa
    18661 tgatacttta gaggactact ttaaaaaaat cacaggagga gagggcattg cttaaactta
    18721 ttcaaacaga atttcttaaa ctgcgtcgta ggaaacttat ttggctgatg ttgttgtctg
    18781 ctctcattat gccgtttttc gcactactat acttcaatta ttttggtaaa acaggtgttg
    18841 agccaataaa gttttataaa tggtctgcat ttggttatac actttggatt attttgcctg
    18901 ttgttttggg tatattttgc accatgctta tacacgaaga aaaccagtat gatatgctca
    18961 aacagctttg gattgtacct attagtaaaa tgggatactt ttttagtaaa tttttcgttg
    19021 ttttgattta ctctatttgt tttatgctga ttacagccgt tgcttctgtg ttatttagtg
    19081 tactttctgg atatgtcgta tttagctggg caagcatttt atatttgttg aaaaaatgtt
    19141 tagaaattgg tgtaatcact gcttttgtaa tgttgccgat tttggcaatc gctacatctc
    19201 aaaaaggata cattctccca atttgtatca cattggtata tgccttttcc ggttttgtta
    19261 taatgacaat aaatatgtat ttacacccat tatccagtat gggagttatt atcatgagaa
    19321 ataaagacat tccaggtctt atattttcac aggaaattaa tgtcccatta gcatttcttt
    19381 gtatttgtat ttggagtatt gtatcagtat tgtttgcaaa tattgcacta ggaagaagaa
    19441 agtgaggtgt agataatgtg gaaattactt tgggctgaat gtcaaaaaat tcgtcgttca
    19501 aaaattgttt ggattacagt ttttgcatcc attatgatag cagtcatagt ttttgcaggg
    19561 gggcaggatg tatataatga cccagattta cattatggct taaagagcgt ttatgacggt
    19621 tcacggtata tagacaatgc aggttggtat atggacgcag tacaaccttg gtcaactttt
    19681 tttgttcttc ctgctgtcat tgccctatta ggaagctata ttatttgtcg tgaagaagag
    19741 gaggacacta ttaaatccct gcgtcttatt cccataaatg aaacaaattt aaccatagca
    19801 aaaatgatta ttacttttat attcagtata cttctttatt tgttactctt tactataaca
    19861 tttttgactg aatccgtttt acatttttcc gatttatcga caaaattggt tttaagttgc
    19921 atgaaagagt attttcttga tggcataggt gtattctttg caatttctcc cattattgcc
    19981 ttggtatcgc gcatgaaaaa aggatattgg cttgcattag tattcacaga agtttattct
    20041 attgctggac tatttgcggg tatgtcaaat gtcttacaaa ccttttttcc tattgcggca
    20101 atatttaata tttctggata ctatataact actggagaaa aaattatggg gagtatcatg
    20161 agtttattac tttgtgcctg cctttctgca tttatactta aagggctaaa acacaatgaa
    20221 aaaaattgaa ataggtatat caaaatgaaa aagataaaaa aactgattat tctaattgta
    20281 ttcttgtttc tttttggcat gttacactgt tatactgaat ggaaattcaa caataaccca
    20341 cctaaagggg taatagaaag aataaatgag tggactgata agattggact ggattagtaa
    20401 cttatgttaa ttatagtgaa tgtaatatta gcaagttatt gtttcgtatt ttaatactat
    20461 aactttaaat atttggtttt aatcttccaa acgaatataa aaaaactgtc acagaggcaa
    20521 catatttttg aatatttata aagtggtagt tttgattttc aaagctaccg ccttttcttc
    20581 tatataagca aacttatcct caacaaagtg taaaacatgg tgcattttaa gaaaaaagta
    20641 ccacagacac aagcaataaa agaaacgccg agaacctaca aaaacgtagt gcttatgcag
    20701 atttacgacg ccttctattt tctcaaccgt cttaatgacc ttgtacaaaa gaaatttttc
    20761 taatattttt tataatctta tcttgtgatg ttttttatgt ataaatgact taataacaaa
    20821 tccaataaaa attatggata ttggtataat tagaacgagg aatttataat cattataatg
    20881 tgacattatt cttacccaac tctcagaaaa aatatatcct atactgatta atgaagtatt
    20941 ccatatggtt attcccacga tagatgatat tacaaaagtt ataatatttt gacctgctat
    21001 acctgctata aaagatatgt atgttctaca taaagggatt aatctacata cacaaacaga
    21061 aatagaagag tatttattaa aataatcttg agatgcaaat attcctttct ttgcctttgg
    21121 acatatctct attattttat ttatgataga tttacctccc caatttccca ctgtataaca
    21181 aaatatcgaa ccaagtatac ctgcaattat acttaaaatt aaaattgtca gaaatccaaa
    21241 atgatttctt gcagcaattg ctccacataa aggtaaaaca acttcgctag gtaatggaaa
    21301 acaagcatac tcaatcataa ttaatacaaa tacagagatt aatccatatt gtaaaataaa
    21361 actattgatt acagacactt acttatctat ctcctttctt atttaaaggt tttaagggta
    21421 catgttctaa ggattctcac cctatattta aagaatcaat ctctttaaac tattatatgt
    21481 atttacacaa agcatttata acatacttta aaaatagtac cttaaaataa gaaacttaat
    21541 aaataaaaaa agattacgtg gctacgtcct actctcccag gcagtttccc accaagtacc
    21601 atcagcgcta gagagcttaa cttctgtgtt cggaatggga acaggtgtat cctctctgct
    21661 attgtaacca cataatcttt atgcttaata tttccattaa gtttttaata agtttataga
    21721 a
//
LOCUS       DAJMZY010000071        21623 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.071, whole genome shotgun sequence.
ACCESSION   DAJMZY010000071 DAJMZY010000000
VERSION     DAJMZY010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 21623)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21623)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21623
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.071"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            <1..210
                     /locus_tag="OE968_002503"
     CDS             <1..210
                     /locus_tag="OE968_002503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219778.1"
                     /translation="AMSELRSLIKQYDEMIHKDWNLATEEQKNRVEKLKCEVDNLKKS
                     DTGDDSKIWVEAIQNIAMKRGVNNG"
     gene            203..1612
                     /locus_tag="OE968_002504"
     CDS             203..1612
                     /locus_tag="OE968_002504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase B"
                     /protein_id="HCP7219779.1"
                     /translation="MDKALLTLLDCYWDNPVWFAEDMLNFKADKWQSDVLMALAQTPK
                     VSIRSGQGVGKTGLESIATVWYLSTRPFPKVVATAPTRQQLYDVLWAEIAKWLSNSKV
                     EKLLEWTKTKVYMKGFEERWWATARTAVKPENMQGFHEDYMLFVVDEASGVADPIMEA
                     ILGTLSGAENKLLLCGNPTRTSGTFYDSHNRDRDLYKTFKVSSLDSPRTSKDNIEMLK
                     RKYHEGSDPWRVRVLGEFPKGESDSLISLEAVETSTIREVNISNDYILNIGADIARYG
                     DDETIIAPRIGGKVFDLLTYSKKDTMETVGNILRAVDKFKNMYHQINRVKIKTDDDGL
                     GAGVTDRLKEVIRHERLKYEVIPIQNGSSAIEKDKYYNKASEMWDNMREELDANLSSF
                     IQNKEAIIQLPNDDKLIKQLSNRKYTVDSKGKIQIESKKEMKKRIGESPDRADAVIYS
                     FAENNNTDLSLLKGGSVWG"
     gene            1603..3105
                     /locus_tag="OE968_002505"
     CDS             1603..3105
                     /locus_tag="OE968_002505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HCP7219780.1"
                     /translation="MGIISYVKKLFKRPAGEIMRMSSGNIGVYKLDDSRVDYELAREL
                     YQNKNANYKLGSSFVRPIVNSTTGFMGVPHFQIEDEEAQYILDEFVLDNTSKMLKTHT
                     DSLKQGDCYIWITREERENPLYPDKKVRLIYNFISPEEVKEIILDPTTKEPIAYILES
                     QNEWTDLGENKRKAKVKQIITAESRFVEVEGDKIEGLEEGETPNVWGFIPIIHFKNEA
                     DETLKYGQSDIEPIEPLLKAYHDVMLHALKGSKMHSTPKLKLKLTDVASFLAHNFGVE
                     DPVKFAKEGGKINLDGHEILFLNKDEEAEFVEVKSAIGDAKELLKLLFYCIVDVSETP
                     EFIFGVHTPSALASVKEQMPIMVNKIRRKREQFTNSWQLLARMVLIMSSNSSGMKYSS
                     YDVTIGWDEVNPRDDKELAETLEKVCSALDKALEGGFISEESTVNFLAQYIDTMSNYI
                     SDDPEIVGEREKIIKTKMLKYRLDDSQGLNDESNEIEKEINKIKDNNGNG"
     gene            3092..4105
                     /locus_tag="OE968_002506"
     CDS             3092..4105
                     /locus_tag="OE968_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219781.1"
                     /translation="MAMDKSTSELITVAGEYKKWALEARKKFIDLRLKQDDEIRTMYI
                     NITRNITKEIRKGNLSDFNKVRLKQILKQLTQEIKILNEQLVFNFDEYLNKNVETATS
                     YSKNILINAVETAQITKVTKTMIQKAFYDINIRTVEAYYTRVKDGLFLSDRIWSKCKK
                     YREDMKVILQTAVTEGQDCVKTAKMLDKYVLKGKKTLVDEYPNMIKRIGNRVPQNISY
                     EALRLARTEMTSAYGDGVLASAMINPATIGIQFMLSMAHPHTDICDEICGEDNFGLGK
                     GVYPINEAPVYPFHPHCLCIMLTVVQPLDILVGRLKNWIKNPMNDVPLEMWYQEVYGN
                     LNF"
     gene            4125..5459
                     /locus_tag="OE968_002507"
     CDS             4125..5459
                     /locus_tag="OE968_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219782.1"
                     /translation="MNVITGEMDSMNALISSIKPSDIPLAKDIDIEALKSIDDDPLEV
                     VVEIPATKSKRGWNYTAKSLKDIVDYTNENTLNGFLGHQKAENISTEFALPVTHWIGA
                     EMKGDKAYFRGLIDADATNLKRWIRTKRIKEVSIFGYPKLKKSAKGEMNVIGYEPLSI
                     DWTPLHRPGMPTSIVGMEMSPNGEQLDGTFEALRIDLREALKAKFSINDNNSYLYIQN
                     IRYDNNTVIYELEQNGLCKLYSIPFTIVENKINLGEEIEVIKKISYEAKGEMKGEENK
                     LEGKELIKNVKGLLQTGEISYSEVIQGIGLTKEIVTGEMEDVKSSLKAEKELREVKKV
                     LGIVGEMDTVEVAKKASKALENEKKEAWNCIVNKVIKDKVSGEIAQTLVKKMLNVEEG
                     SSEEVITGEIENILNDEFVKNTMSNMYKDNPTTTGLLNSSNNGSLTTKKNRI"
     gene            5475..5858
                     /locus_tag="OE968_002508"
     CDS             5475..5858
                     /locus_tag="OE968_002508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2190 family protein"
                     /protein_id="HCP7219783.1"
                     /translation="MAFKGQPTPSTITQITRAKISDGKSVRVILSEGESTKTQQFYLI
                     NGFFGVAMQDGEKGDEVTLQIEQAEYETDNIVTSEAFEAGKLIYWDNTAKKFTTTSAS
                     NRLVGRVTDGKDSNNVIWFILLPQQ"
     gene            5877..6914
                     /locus_tag="OE968_002509"
     CDS             5877..6914
                     /locus_tag="OE968_002509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate ammonia-lyase"
                     /protein_id="HCP7219784.1"
                     /translation="MAFKVISQENLLEQKRKETLQEDIPFIVNGEMEYVTKKISNGEM
                     ETLELNKPLGEMMTFSSTSNLKELLRKVVLDVELGREQVQLLYKPIYDSIADSNLPQV
                     MDAKWALQGNCVFLEHIEGEEIKFGTINAENGPVARIQTYATGFEYTKEMKDFNQTFS
                     VEILNKSIGESYNALLNHIHLSPIINFNYKASNKTAFKGETNDPIWLGIWRTLTQAQK
                     DTVIAKRQGNILMASSADQIEIEMALNGGHLLNGSMYPSIKNISTVIYYDGWEVTVGK
                     KTYSYKGVTPGKGYLIRPKRGFKELIKRDLTTEVGNADLSKLVENQIVGHCYRGAFAA
                     VEENVQEISFR"
     gene            6954..7292
                     /locus_tag="OE968_002510"
     CDS             6954..7292
                     /locus_tag="OE968_002510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219785.1"
                     /translation="MTPARDLIEKLRLLLNDKDKKSFTDEELNLFLEEADCIYCAASQ
                     GWILKSLQYENTVGEMYEYKVGQETYKSSSIKDLVSVAYQNADKFKDMCTNKKEKGSF
                     MLGISTEFEI"
     gene            7289..7666
                     /locus_tag="OE968_002511"
     CDS             7289..7666
                     /locus_tag="OE968_002511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219786.1"
                     /translation="MINIDRRRKDIIRTININPTNITITSIKKTEIDGAFEETETEIK
                     CVVRIFNEKTAEKQISSEKQGTFSSIRTYGMLVSNDVILEVNSRDSLEFECIYGRMKI
                     VNIYPQIVKGELCGYQCSLERID"
     gene            7668..8078
                     /locus_tag="OE968_002512"
     CDS             7668..8078
                     /locus_tag="OE968_002512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219787.1"
                     /translation="MSAFTNAINDINRKKAGMLVLCMSASAMLEGEAKANARWTDRTS
                     HARQSLNAKTLSGGNNFIIRLSHGAEYGGILEEGSKPHVITPKSAQALYWRGASHPVK
                     SVQHPGTKATPIIKPTIDKNIGKIGNMIFRYWSD"
     gene            8079..8900
                     /locus_tag="OE968_002513"
     CDS             8079..8900
                     /locus_tag="OE968_002513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219788.1"
                     /translation="MRAGIRKALIDNIKELKGCYEPNVPNKDTKKPYMVVVQGQDNDH
                     GETIGFERSIEVWIYEGRTTFKKLDKLTKQVVEVLDMNTIVDESENEAFTCIYKGTSE
                     NDIVVEEWDAIARGIRFSVIALEDKEDTTNDRWVEALSRHTKDLLEIESYKDNWKKNF
                     IAPCALWRTTHIENKRINYHLIEITKTMKCHVVSKNKDEIVKLLETLETSLIIDKRVR
                     LREDKNMYLTLVSVVEDRESDMFTTGQLTAVFKMIGKIKREGPTMDKIYGNGNLK"
     gene            8913..9116
                     /locus_tag="OE968_002514"
     CDS             8913..9116
                     /locus_tag="OE968_002514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219789.1"
                     /translation="MAETNNKKINVSKQEEKYLKSDFIKNSEALGYGKMVVAGALFNC
                     KKEELTKAEFEKLIKDFLEREVK"
     gene            9118..10539
                     /locus_tag="OE968_002515"
     CDS             9118..10539
                     /locus_tag="OE968_002515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail sheath subtilisin-like
                     domain-containing protein"
                     /protein_id="HCP7219790.1"
                     /translation="MATGTWNEKERKEIPGFYNRFKTQAEKSTNTGLKGRLAMPIRAN
                     WGDVGKVVTIKNDLRQLKNLFGDDMNYSAFKLGKLALLGNVKELLLYRLVDGNQKKGT
                     LTLKDTTENSAKDVIKLETKYPTARNFNVTIKSNLVDSDKKDFIFFENTKQLFSSSIK
                     GTIDEIVLEINSNLDNEYVIATKVADSDTILANVVNQALEGGNDGCTSITNESYLKAL
                     EEFERYSFDSFVLDGVADEALQETTKAWVAKNKELGKDILLFLGGKTEDNIKQINDKS
                     KSFNDENIVNVGSSAYYENIKYTPSEVAVYIAALSVSKGITGSICNAKTIFEEVEPRL
                     SQSEVKECLKSGTLVLDFDDGDVIIVDDVNTFKKYVDDKNEAMGYISNIMFINTINKD
                     TSLKRKEFVGKIFNDATGQTTVICALKKYFEELMSQGIISEFNVDIDTELQATAKADE
                     FYWKWDAVKVDVMKKIYGTGYLG"
     gene            10555..10968
                     /locus_tag="OE968_002516"
     CDS             10555..10968
                     /locus_tag="OE968_002516"
                     /inference="COORDINATES: protein motif:HMM:NF020949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219791.1"
                     /translation="MYNDDYIEEASFLNGSDVVILIDGVEELYMEEIKADFEQDEQSI
                     KLLGCQNEISRVGTTKGSFSLNGYKTDSKFAKLGFRSFEIIYNLSNSETLGYESIRLK
                     NCRLKKLPLINSKAGEIVKIEVEGSFRGYDLLNEL"
     gene            11052..11543
                     /locus_tag="OE968_002517"
     CDS             11052..11543
                     /locus_tag="OE968_002517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219792.1"
                     /translation="MSEIYKRELENEVVEDNDLDEEIEETNEDRLKMKEDEIIAKLLE
                     DSPVPQRTVFLDRLGIPITLKALTEKEISKIRKECTKIVKVQGRREEKLNDDEFTLAL
                     IEKGTVKPNFSNQKLLNAMKVTNAREFIKRKFLAGELSKISDQILELSGFYDEISDDD
                     IKN"
     gene            11720..15994
                     /locus_tag="OE968_002518"
     CDS             11720..15994
                     /locus_tag="OE968_002518"
                     /inference="COORDINATES: protein motif:HMM:TIGR01760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HCP7219793.1"
                     /translation="MREIAKKEMYHIDVVISAKGDGETKSKLSAMEKYMKQTEKRMQT
                     LNRIKVNPAIKATDKASSVVNRVNNNMNKAKKTVTARIKATDNASPVANRASNNVNKA
                     KKTVTARLKATDNASSTVNKVNNKIKEVAKPVPPVIIRGQDESSSIIDKVKAKIQNLK
                     ADTIIKIKSQADEAINTISRTKNKLQEFVSKRYEAAVKIRDEASSALRGLTGKIDSFV
                     SGAISKFARLATTAGALIGGIGVGSAVKGFATFEQSMKNTQAVSGATGKEMEALTAKA
                     RQLGRETSFTAKDAGDAMYYMGMAGWKSEQMIKAIPDVLNLAAAGGTDLALTSDIVTD
                     GLTALGMTANDTTEFVDVMAATITNSNTSVELMGETFKYVGSMGGALGVSMKDLSLAT
                     GLMASASVKGSMAGTSLRGGLVRLIKPPEEAASAIKKYGIELKKNKNGSLDLAGTIGS
                     LREKLGGLKDVEKGVAISSIFGRTAMAGWAAVVNASESDFNKLTTAIAESEGEAKRIA
                     DMKLDTLSGQFEILKSAIDDVRISVGQRLGPMTRGFVEDLIKKMPQIGDAIVGVVEKF
                     VNNFDKIKAGFQVLLPAIGSVIASVMVLKATFAFGGAIKSLSLLASTFGTAKLVAFGL
                     TVGIGAIVIAFAGMTVAISNNKTAMMDLQTRFGSFGEYVTTIMETVGGVIKLTLGNLL
                     IMLGGIGKGIGILLSDKSWDEKASSLKNLFGKTTAEIKTNTKEALSDINGETSNATAL
                     LKKSTSKELQGVTKAFSTAFDQSKNVTEKKSSDIARALTNGLKGLDDQSLTMMRGLND
                     NMAIILSGVTADMKPSDKVNKITKNLDDAFKAGKLSAQEYRSSIQETLNFISKYSADS
                     SNNLKQGMSDAFNAFKEGTNIGGLKDGVTGMLNSLKATGPQALETLKGLGGKASEIFK
                     GVDFNSSIDAQKTKVLQNLNSLGLEGTQAIDTLRTIFSQASSALDTTNLKQGLSNTFN
                     SFKEGFNSGGIKNAINSMLGTINQAGPQMQQALGKMDGKMGQVFANVDFSTPIETQAS
                     KVLENLNNLGIEGPKALETVRSIFAQASSQIQGSASQTAQQANQEVANALTQGNPAVQ
                     QAGQQLGTDLTNGVVNGVQAGVPVVQQKSNELATATQNGVTNAVNSATPQIDNSNLTS
                     GIDTAFNQATATVQQGASSMYNGAKQSFTQLAQIGREAGSSLYNGATTSFNMLATNVR
                     VACSSMYNGARTSFTSLSSSAISAISAMCSSVVSQVSAMSSQIISYWNSVRATVSAPI
                     TASFNVKTTQTTVKRTVNESSGGILGNILDRFADGGVATRTSICGENGAEMVIPLTNT
                     RRSRAIELYEQTGKMLGLGSTPSQKVGNSNIVNNVRQFPLANVLDTDNKEYKEATPNS
                     VNSSNNTINLGGISINVQNSDNKEEMIQELLSQVESGIREALQDIG"
     gene            16076..16819
                     /locus_tag="OE968_002519"
     CDS             16076..16819
                     /locus_tag="OE968_002519"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219794.1"
                     /translation="MWQKFKSMNGILKIIIGIIAIILLPITLVLLSIEFLVKAIGSKK
                     KAKIALGCILVFLTTLCTRNVYNVLSIEKEEHIPVKQVSYNDKDKGKSENNIQEQQQK
                     KEESKKLEEQKKNEEKEQNNEPTKFFTDVYLKNKNCVNMTSYEGIKSNLDIFGYKYEV
                     IEPNETTLRQINVYDNQSNDTIQFQFYENDTGEEVVTVMQYNKKDEPDKSVAISDGFH
                     TQPPKFQNHINNTNKEVNSIEEQINFMFN"
     gene            16888..17559
                     /locus_tag="OE968_002520"
     CDS             16888..17559
                     /locus_tag="OE968_002520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HCP7219795.1"
                     /translation="MVIDIYLKNEKEKIDFHFPVNPQDSLSIKKEKRFETVDIVNLGE
                     FDIKKEGEKIREISFKTFLPNLYDASYCRYSELKNPIEVVAMLEKWVDQAEPLRLIIT
                     GFGYNGLVTISSFSNTQTAGREEDRDIEITFRTYRELKIETLKKDTKSNTKTDLKDNR
                     PNTQTKSKIYTVKASDTLYKIAKNLLGKGSRWPEIYNIPENKKVIGKNPNIIKKGQKL
                     VIPSK"
     gene            17556..18518
                     /locus_tag="OE968_002521"
     CDS             17556..18518
                     /locus_tag="OE968_002521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdQ"
                     /protein_id="HCP7219796.1"
                     /translation="MKIILNGKYDIANFNEGITLSEAIDGVAYKMDVSLVEPKQLKDI
                     NIKKGDKIILIDIAYESKKEETIFDGVVWETRRSEKSKKLTLSCRERTVYMEESEEQY
                     QFKENTATQRIEYYCKQWNIPYYNLANTGKKLAKVIHKTNILDMIKKDLKETATKGGD
                     LFRVRMDNKLKLFKLGTNANVYKLDSILEDANFTSSFNDAVTSVKVLGKSKDENTKAP
                     IIGTYKKDADKFGTLQKIKQDEKIKNAKEAKKAAEAMFNSGEETISVDCAVDINRIRA
                     GDKVSLKSKEYYVIDVTHTLDSRPKMKLNIGSLEYIRRKFYNND"
     gene            18511..18876
                     /locus_tag="OE968_002522"
     CDS             18511..18876
                     /locus_tag="OE968_002522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219797.1"
                     /translation="MTDARFNGIARILKENMNKSVANGTFGMGCELAEITANGLKVNG
                     YKDEIQDYLVLENLTLKEDYFTFSDEALSGEYRHKHKIETPKELKPLRIGDNVLVAVM
                     GAEFVVIGRVVNAKPISSK"
     gene            18851..19309
                     /locus_tag="OE968_002523"
     CDS             18851..19309
                     /locus_tag="OE968_002523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2634 domain-containing protein"
                     /protein_id="HCP7219798.1"
                     /translation="MPNLFPQSETFETVELKNNDENELDLKGSFLFDFEKGEFVKNAD
                     GTLKKCDKVQAYKQWCQKAILTPRYKKAAYTNIYGSEIKDLIASNLSQSAKELEITRL
                     IKETILVHPYTKEVGEFSFNWLENSRLVEYEFDVLTIDDENIVIDGNIKR"
     gene            19318..20454
                     /locus_tag="OE968_002524"
     CDS             19318..20454
                     /locus_tag="OE968_002524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate J/gp47 family protein"
                     /protein_id="HCP7219799.1"
                     /translation="MERELPIPVFLTEDEDSVHERMLSNFQDVSTLEGDFIYDATRPT
                     AEQIAELKQLGLQNNLKIAFPQTSYGTYLEWLGECKGVFKNQPTKATGVITFTGVQGT
                     IITKGTIVTTIATDEKQSIEFELLETKTIGENETVDIKAESRIVGTIGNVSKGSISVL
                     LGSISGVKSITNKEDFRGGTDIEDEEHFRERVLVAEQEDKLSGASSDYIRWAKEVDGV
                     GYAYVVSEWAGAGTVKVLILDKNRKAATQELIDKVQEYIYPLNISEGENRDGKAPIGA
                     LVTVVTPDTLLINVKASFIFSNGFSEETVLNNLKTKIDKYLDKIDLGGTVSYNAIQAI
                     VGSMMLTDEGIEDFSNLTINDVKENIKLQDQVVGIGEIVNEVVG"
     gene            20451..21080
                     /locus_tag="OE968_002525"
     CDS             20451..21080
                     /locus_tag="OE968_002525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012705217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YmfQ family protein"
                     /protein_id="HCP7219800.1"
                     /translation="MIASKKGKEMLLTLSPIYEQSIIMQSLYEAIGSEFDNLELLDEE
                     IELQLFPQSATWGLGFWENRVGLITNLDEDMETRRRKVIAKLQSKYIMTPKRMSMILQ
                     SYTGANIKINENISPYTFGVELTSTQGFPKDLEDLYKRVNVIKPSHLAVSYKLVSLLK
                     SKTYFAQTAIMSEEITIYPYTSKEVKASVKAKFALAHNMSSETLTVYPR"
     gene            21093..>21623
                     /locus_tag="OE968_002526"
     CDS             21093..>21623
                     /locus_tag="OE968_002526"
                     /inference="COORDINATES: protein motif:HMM:NF023985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HCP7219801.1"
                     /translation="MADEQFYTILTNIGKAKIANAGMLGKPVVLEKIQAGDGGGNYYN
                     PTEEQTALKNKVWEGNINAFDNDENNPNWIIATACIPGSIGGFTVREMGLIDNEGDMI
                     AICKSPETYKPKIDNGAMKDLYLKFIIEVSNVEKVTLVVDPTAIFLTKKDEEKILTNI
                     NKLDTKIDTTKIELTSN"
BASE COUNT         8854 a         2439 c         4283 g         6047 t
ORIGIN      
        1 gctatgagtg agttaaggag tttaattaaa cagtatgatg aaatgattca taaggattgg
       61 aatttagcta cagaggagca gaaaaataga gttgaaaagt taaaatgtga agttgataac
      121 ctaaagaaaa gtgatactgg agatgattca aaaatttggg ttgaagctat acaaaatatt
      181 gcaatgaaac gtggtgttaa caatggataa agctttattg acactattag attgttattg
      241 ggataatcct gtttggtttg cagaggatat gttaaatttt aaagctgaca agtggcaatc
      301 tgatgttctg atggctttag ctcaaacccc aaaagtatct attagaagtg gtcaaggagt
      361 aggtaaaact ggattagaaa gcattgcaac tgtatggtat ttaagcacta gaccttttcc
      421 gaaagtagtt gctacagctc caacacgaca acaattatat gacgtactat gggctgaaat
      481 agctaaatgg ctaagtaata gcaaggttga gaagctactt gagtggacta aaacaaaagt
      541 gtatatgaaa ggctttgaag aaagatggtg ggctacagct agaacagcag taaagcccga
      601 gaatatgcaa ggttttcatg aagattatat gttatttgtt gttgatgaag cttcgggagt
      661 tgctgacccc attatggaag ctatattggg aacattatca ggtgcagaaa ataagcttct
      721 tttatgcgga aacccaacta gaacgagtgg aacgttttac gatagccata atagagacag
      781 agatttatat aaaacattta aagtatcttc tttagacagc cctagaacat caaaagataa
      841 tattgaaatg ctaaaaagaa agtaccatga aggttctgac ccttggcgtg tcagagtact
      901 tggagagttt ccaaaaggtg aaagtgattc tttaatatct ttagaagctg ttgaaacaag
      961 cacaataaga gaagtgaata tatctaatga ctatatatta aatatagggg cggatatagc
     1021 aagatatggt gatgatgaaa ccataatagc tccaagaata ggtgggaaag tatttgattt
     1081 attaacttat tcaaaaaaag atacaatgga aacagtagga aatatattaa gagcagttga
     1141 taaatttaaa aatatgtatc atcaaattaa cagagtaaaa ataaaaacgg atgatgatgg
     1201 cttaggtgca ggtgtaacag atagattaaa agaagttata agacatgaaa gacttaaata
     1261 tgaagttata cctattcaaa atggttctag tgctatagaa aaagataagt actataataa
     1321 agcttctgaa atgtgggata acatgaggga ggaattagat gcaaatttaa gtagttttat
     1381 acaaaataaa gaagctataa tacagcttcc taatgatgat aaacttatta aacaactatc
     1441 aaatagaaaa tatacagtag attcaaaagg gaaaatacaa atagaaagta aaaaggaaat
     1501 gaaaaaaaga attggagaat cacccgatag agctgatgca gtaatatatt cgtttgcaga
     1561 aaataacaat actgatttat ctttactgaa agggggtagt gtatggggat aatatcttat
     1621 gtaaaaaagc tatttaaaag acctgcagga gagattatgc gtatgtctag tggaaacatt
     1681 ggcgtatata aattagacga ttctagagtt gattatgagt tagcaagaga actgtatcaa
     1741 aataaaaatg ctaattacaa gttaggttct agttttgtta gaccgattgt caattcaaca
     1801 actggtttta tgggtgtacc tcattttcaa atagaagatg aagaagctca atatatatta
     1861 gatgaatttg ttttagataa cacatctaaa atgttaaaaa cacatacaga tagtttaaag
     1921 caaggtgatt gttatatttg gataactaga gaagaaagag aaaatccttt atatcccgat
     1981 aaaaaagtta gattaatata taacttcata tcacccgaag aagtgaaaga aataatatta
     2041 gaccctacaa caaaagagcc tatagcttat atattagaaa gtcaaaatga atggactgac
     2101 ttaggagaaa acaagagaaa ggctaaggta aaacaaataa taactgctga aagtagattt
     2161 gttgaggttg aaggtgataa gatagaaggt ttagaagaag gggaaacgcc taatgtatgg
     2221 ggttttatac caataataca ttttaaaaat gaagctgatg aaacattgaa atatgggcaa
     2281 agtgatatag aaccaataga acctctttta aaagcttatc atgatgttat gttacatgcg
     2341 ttaaaaggta gcaaaatgca ctctactcca aaactaaagt tgaaattaac tgatgttgca
     2401 agttttttag cacacaattt tggtgttgaa gacccagtta aatttgccaa agaaggtgga
     2461 aagataaatc ttgatgggca tgaaatacta ttcttaaaca aagatgaaga agctgagttt
     2521 gtagaagtaa aatcagccat aggtgatgct aaggagcttt taaagcttct tttttattgc
     2581 atagtagatg tatctgaaac acccgagttt atatttggag tacatacacc tagtgcttta
     2641 gcttctgtaa aagaacaaat gcctattatg gtaaataaga taagaagaaa aagagaacaa
     2701 tttacaaata gctggcaatt acttgcaaga atggttttaa taatgagttc taattctagt
     2761 ggtatgaaat attcatctta tgatgtgact ataggttggg atgaagtaaa tccacgagat
     2821 gataaagaat tagctgaaac actagaaaaa gtatgtagtg cattagataa agctttagag
     2881 ggtggattta ttagtgaaga atcaacagta aactttttag cacagtatat agatacaatg
     2941 agcaattata taagtgatga ccctgaaata gttggagaaa gagaaaagat aataaaaacc
     3001 aagatgttaa aatacagatt agatgactct caaggtttaa atgatgagtc aaatgaaatt
     3061 gagaaggaaa taaataaaat aaaggataat aatggcaatg gataaaagta cttcggaatt
     3121 aataactgtt gcaggggagt acaagaaatg ggcattagaa gctagaaaaa aatttataga
     3181 tttaaggctc aagcaagatg atgaaataag aacaatgtat attaacataa caagaaatat
     3241 tacaaaagaa ataagaaaag gaaatctttc agactttaac aaagttaggt taaaacagat
     3301 actaaaacaa ttaacacaag aaataaaaat attaaatgaa caactagtat ttaattttga
     3361 tgaatactta aataaaaatg ttgaaacagc tactagttac tctaaaaata ttttaattaa
     3421 tgcagttgag acagctcaaa taactaaagt aactaaaact atgatacaaa aagctttcta
     3481 tgatattaat ataagaactg tagaagctta ttatacaagg gttaaggatg gtttattttt
     3541 atctgataga atttggtcta agtgtaagaa gtacagagaa gatatgaaag ttatattaca
     3601 aacagcagta acagaaggtc aagactgtgt taaaacagct aagatgttag acaaatatgt
     3661 tttaaaaggt aagaaaactt tagttgatga atatccaaat atgataaaaa gaataggaaa
     3721 tagagtacct caaaatataa gttatgaagc tttaagattg gcaagaactg aaatgacatc
     3781 agcttatggt gatggggttt tagcttctgc aatgattaac cctgcaacca taggtattca
     3841 gtttatgttg tccatggcac atcctcacac agatatatgt gacgaaatat gtggagagga
     3901 taattttggt ttgggtaaag gtgtttatcc tataaatgaa gctcctgtat atccattcca
     3961 ccctcattgt ttgtgtatta tgcttactgt agttcaacca ttagatatat tagttggaag
     4021 gttgaaaaat tggattaaaa atcctatgaa tgatgtacct cttgaaatgt ggtatcaaga
     4081 ggtgtatgga aatttgaatt tttaaattga aaggtggtga ttaaatgaat gtaataactg
     4141 gagaaatgga ctcaatgaat gcgttaatat ctagtataaa accttctgat attcctttag
     4201 ctaaagatat agacatagaa gctttaaaat ctatagatga tgaccctctt gaggtagttg
     4261 ttgagatacc agctacaaaa tctaaaaggg gatggaatta tactgctaaa agcttgaaag
     4321 atattgtaga ttacactaat gaaaatactc ttaatggctt tttaggacat caaaaagctg
     4381 aaaatatatc aactgaattt gcactacctg taacgcattg gataggtgca gaaatgaaag
     4441 gggataaagc ttatttcaga gggctgattg atgctgatgc aacaaattta aaaagatgga
     4501 ttagaactaa aaggataaaa gaagttagta tatttggtta tccaaaactt aaaaagagtg
     4561 ctaaaggcga aatgaatgtt ataggatatg agccactatc tattgattgg actcctctac
     4621 atagaccagg tatgccaaca agtattgtag gtatggaaat gagtcctaat ggcgaacagt
     4681 tagatggaac ttttgaagct ttaagaatag atttaagaga agctttaaaa gctaagtttt
     4741 ctattaatga taataattca tatctctata tacaaaacat aagatatgat aacaatactg
     4801 tcatatatga gttggagcaa aatggattat gcaagcttta tagtatacca tttactatag
     4861 ttgaaaataa aataaatcta ggtgaagaaa ttgaagtaat aaagaaaata agctatgaag
     4921 ctaaaggaga aatgaaagga gaggaaaaca aattggaagg aaaagagtta ataaaaaatg
     4981 tcaaaggatt actgcaaact ggtgaaatat catattcaga ggtcatacaa ggaataggct
     5041 taactaagga aattgtgaca ggagagatgg aagatgtaaa aagttcatta aaagcagaaa
     5101 aagaattaag agaagtgaaa aaagtacttg gaatagtagg agagatggac acagttgaag
     5161 tggcaaaaaa ggcttcaaaa gctttagaaa atgagaaaaa ggaagcttgg aactgtatag
     5221 ttaataaagt aattaaagat aaagtgtcag gtgaaatagc tcaaacatta gttaagaaaa
     5281 tgttaaatgt tgaggaaggc tcaagtgaag aagtaataac aggagaaata gaaaatatat
     5341 taaatgatga gtttgtaaaa aatacaatgt ctaatatgta taaagataat ccaacaacaa
     5401 caggattatt aaactctagc aataatggaa gtttaacaac taagaaaaat agaatataaa
     5461 ggagtgatgt ttatatggca tttaaaggtc aaccaacgcc aagcacaata acacagataa
     5521 caagagcaaa aataagtgat gggaaatctg taagagttat tctttcagaa ggtgaaagca
     5581 ctaaaacaca acaattttat cttataaatg gattctttgg agtcgctatg caagacggag
     5641 aaaaaggcga tgaagttact ttgcaaatag agcaagctga atacgaaacg gataatattg
     5701 ttacatcaga agcttttgag gcagggaaat tgatttattg ggataataca gctaagaaat
     5761 ttactactac atctgcaagt aataggctag ttggtagagt aacagatggg aaagacagta
     5821 ataatgtaat ttggtttata ttattacctc aacaatagaa aaggagtgat aaatatatgg
     5881 catttaaagt aattagtcag gaaaatttgc tggaacaaaa aagaaaagaa actttacaag
     5941 aagatatacc atttatagta aatggtgaaa tggaatatgt aacaaagaaa atatcaaatg
     6001 gagaaatgga aaccttggag ttaaataagc cacttggtga aatgatgact tttagctcga
     6061 cttcaaattt aaaagagtta ttaagaaaag ttgtattaga tgttgaacta ggcagagagc
     6121 aagtacaact attatataaa ccaatctatg acagtatagc agattctaat ttaccacaag
     6181 ttatggatgc taagtgggct ttacaaggta actgtgtatt cctagagcat atagaaggtg
     6241 aagaaattaa attcggtaca ataaatgcag aaaatggtcc agttgcaagg atacaaactt
     6301 atgcaactgg ttttgagtat acaaaagaaa tgaaggattt taaccaaaca tttagtgttg
     6361 aaatattaaa taaatcaatt ggtgagagtt acaatgcctt gttaaaccac atacatctaa
     6421 gcccaataat aaattttaat tataaagctt ctaataagac agcttttaaa ggtgaaacta
     6481 atgacccaat atggctagga atttggagaa cattaacaca agcacaaaaa gatacagtta
     6541 tagcaaaaag acaaggtaat atattaatgg cttctagtgc tgaccaaatt gaaatagaaa
     6601 tggcgttaaa tggaggacat ttattaaacg gaagcatgta tccatctata aaaaatatat
     6661 caacagtaat ttattatgat gggtgggagg ttactgttgg taaaaaaaca tattcttaca
     6721 aaggtgttac accaggcaaa ggatatttga taagacctaa gcgaggattt aaagagttaa
     6781 taaagagaga tttaacaaca gaggttggaa atgctgattt aagtaagtta gtagaaaatc
     6841 aaattgtagg tcattgttat agaggtgctt ttgcagcagt agaagaaaat gtacaagaaa
     6901 taagttttag ataaaacact cataagagtg ttatttttat gaggtgataa tatatgacac
     6961 cagctagaga tttaatagaa aaattaagac tattattaaa tgataaagat aaaaaatcat
     7021 ttacagatga agaattaaac ttgtttttag aggaagcaga ctgtatttac tgtgcagctt
     7081 ctcaaggatg gatattaaaa tctttacaat atgaaaatac agtaggggaa atgtatgagt
     7141 ataaagtggg tcaagaaaca tataaaagct ctagtataaa agacctagta tctgtagctt
     7201 atcaaaatgc agataaattt aaggatatgt gtactaacaa aaaagaaaag ggaagtttta
     7261 tgttaggaat tagcacagaa tttgaaatat gataaatatt gatagaagaa gaaaagatat
     7321 aataagaact attaatataa accccactaa tattactata actagtatta aaaaaaccga
     7381 aatagatgga gcttttgaag aaactgaaac agaaataaaa tgtgttgtta gaatatttaa
     7441 cgaaaagaca gcagagaagc aaatatcaag tgaaaagcaa ggtacattta gttctattag
     7501 aacatatgga atgttagtaa gtaatgatgt tatcttagag gttaacagta gagattcttt
     7561 agagtttgag tgcatatatg ggagaatgaa aatagttaat atatatcctc aaattgtaaa
     7621 aggagaactt tgtggatatc aatgttcact tgaaaggatt gattaaaatg agtgctttca
     7681 caaatgcaat aaatgatata aatagaaaaa aagcaggtat gcttgtactt tgtatgagtg
     7741 caagtgcaat gctagaaggt gaagctaaag caaatgcacg ttggacagat agaacatcac
     7801 atgcaagaca aagtttaaat gctaaaacac ttagtggagg aaataatttt atcattagat
     7861 tatctcatgg tgcagaatat ggagggatac ttgaagaagg ctcaaaacca catgttatta
     7921 ctccaaaatc agctcaagcc ctatactgga gaggtgcttc acatcctgta aaatcagttc
     7981 aacatcctgg tacaaaagca acgcctatta taaaaccaac tattgataaa aatataggta
     8041 aaataggtaa tatgattttt aggtattgga gtgattaaat gagggcagga ataagaaaag
     8101 ccttaataga taatataaaa gaattgaaag gttgttatga acctaatgta ccaaacaaag
     8161 atactaaaaa accttatatg gtagttgtac aagggcaaga caatgaccat ggagaaacaa
     8221 taggttttga aagaagtata gaagtatgga tttatgaagg tagaacaaca ttcaagaaat
     8281 tagataaatt aactaaacaa gttgttgaag tcttagatat gaatactata gttgatgaat
     8341 ctgaaaacga agcttttact tgcatttata aaggtacaag tgaaaatgat attgttgttg
     8401 aggaatggga tgctatagca agaggtataa ggtttagtgt aatagcttta gaagataaag
     8461 aagatacaac taatgatagg tgggtagaag ctctatctag gcacacaaag gatttattag
     8521 aaatagagag ttataaagat aattggaaga aaaactttat agctccatgt gcattatggc
     8581 gaactacaca tattgaaaat aaaagaatta actatcattt aattgagatt actaaaacta
     8641 tgaaatgtca tgttgtaagt aaaaataaag atgaaatagt taagcttctt gaaacattag
     8701 aaacaagctt aataatagat aaaagagtaa gacttagaga agataagaat atgtatttaa
     8761 ctcttgttag cgtagttgag gatagggaat cagatatgtt tacaactgga caattaacag
     8821 ctgtgtttaa aatgatagga aagataaaaa gagaaggtcc tactatggat aaaatttatg
     8881 gtaatggaaa tttaaaatag gaggtgcaag aattggctga aacaaataat aaaaagatta
     8941 atgtaagtaa gcaagaagaa aaatatttga aaagtgattt tataaaaaat agcgaagcac
     9001 ttggctacgg aaaaatggta gttgcaggtg ctttatttaa ttgtaagaaa gaagaactta
     9061 caaaagcaga atttgagaaa ttaataaaag atttcttaga aagagaggtg aaataaaatg
     9121 gcaactggta catggaatga aaaagaaaga aaagagatac ctggttttta taacaggttc
     9181 aagactcaag cagaaaaatc tacaaacaca ggattaaagg gtagattagc aatgcctatt
     9241 agggctaatt ggggagacgt tggcaaggtt gtaacaataa aaaatgattt aagacagctt
     9301 aaaaatctat ttggggatga tatgaattat tcagctttca agctaggcaa attggctctg
     9361 ttagggaatg taaaagagtt attactatat agacttgtag atggaaatca aaagaagggt
     9421 acattaacac taaaagatac tacagaaaat agtgcaaaag atgtaattaa gttagaaact
     9481 aagtatccaa cagctagaaa ctttaatgta acaataaaat ccaatttagt agattcagat
     9541 aaaaaggact ttatattctt tgaaaatact aaacagttat ttagttcaag tattaaaggc
     9601 actatagatg aaatagtact agaaataaac tcaaatttag ataatgagta tgtaattgca
     9661 actaaagtag ctgatagcga tacaattcta gcaaatgtag taaatcaagc tttagagggt
     9721 gggaatgatg gttgcacatc tattactaat gagtcttatc taaaagcact agaagaattt
     9781 gaaagatata gttttgactc ttttgtactt gatggtgtgg ctgatgaagc attgcaggaa
     9841 actacaaaag cttgggtagc taaaaataaa gaattaggaa aagatatact actttttcta
     9901 ggtggaaaaa cagaggataa tataaaacag ataaatgata aatcaaaaag tttcaatgat
     9961 gaaaatatag ttaacgttgg aagctcagct tattatgaaa atataaaata tacacctagt
    10021 gaagtagctg tttacattgc tgctctttct gtaagtaaag gtataacggg tagtatatgt
    10081 aatgcaaaaa ctatatttga agaagtagaa ccacgattaa gtcaatcaga agttaaagag
    10141 tgtttgaaaa gtggtacatt ggtcttagat tttgatgatg gagatgtgat tatagttgat
    10201 gatgtgaaca catttaaaaa atatgtagat gataaaaacg aagcaatggg atatatctct
    10261 aatatcatgt ttattaatac tataaataaa gatacttcat taaaaagaaa agagtttgta
    10321 ggtaagatat ttaatgatgc aacaggtcaa acaactgtta tatgtgcatt gaagaaatat
    10381 tttgaagaat tgatgagtca aggtattata tcagaattta atgttgatat agatacagag
    10441 cttcaagcaa ctgccaaagc agatgaattt tactggaagt gggatgctgt taaggttgat
    10501 gtcatgaaaa aaatatatgg tactggatac ttaggataaa ggaggttata gattatgtat
    10561 aatgatgatt atatagaaga agccagtttt ctgaatggtt ctgatgtagt tatacttatt
    10621 gatggtgtag aagagctata catggaagaa ataaaagctg attttgagca agatgagcaa
    10681 agtattaaac tgttagggtg tcaaaatgaa atatcaaggg ttggtactac taaaggttca
    10741 ttctccttga atggatataa gacagattca aaatttgcaa aattaggatt taggtctttt
    10801 gaaataatat ataatttatc taattctgaa acattaggat atgaaagtat tagattaaag
    10861 aattgtagat taaaaaaatt gcctcttata aattctaaag ctggtgaaat tgtaaaaata
    10921 gaagtagagg gaagttttag aggatatgat ttgttaaatg aactttaaaa caaaataatg
    10981 ttgtacttta aagctatgaa caattaattt tgtttgtagc tttttaaaat taaaaatatt
    11041 ggaggaatag tatgtcagag atatataaaa gagagttaga aaatgaagta gtagaagata
    11101 atgatttaga tgaagaaata gaagaaacaa atgaagatag attgaagatg aaagaggatg
    11161 aaataatagc aaagctattg gaggattcac cagttcctca gagaactgtg tttttagata
    11221 gattaggaat accaattact ttgaaagcat taacagaaaa agagattagt aaaataagaa
    11281 aagaatgcac taaaattgta aaggtccaag ggcgaagaga agaaaaatta aatgatgatg
    11341 agtttactct agcattaata gaaaaaggaa ctgtaaaacc taatttttct aatcaaaaat
    11401 tacttaatgc tatgaaagta acaaatgcta gagaatttat aaagagaaaa ttcttagctg
    11461 gagaattaag taaaataagt gaccaaatat tagaattatc cggtttttat gatgaaataa
    11521 gtgatgatga tataaaaaac taataaaaat ggggggacga ctgactgttt taaataacat
    11581 ctttgtcaag catcatgttc ccccagatgt ttatgttaag aaaaatttaa tgtctcaacg
    11641 cttaatgaaa gtatttactc aaaatgaaat agagcaagag aataaagcta tgaaaaaata
    11701 aatatctaca gaaaggtagg tgagggaaat agctaaaaag gaaatgtatc atattgatgt
    11761 tgtcataagt gcaaaaggcg acggagaaac aaaaagcaaa ctaagtgcta tggaaaaata
    11821 catgaagcag acagaaaaaa ggatgcaaac acttaatagg ataaaggtta atcctgctat
    11881 aaaagctact gataaagctt caagtgttgt aaatagagtt aataacaata tgaataaagc
    11941 aaaaaaaact gttacagcta gaataaaagc tacagataac gcgagtccag tagccaatag
    12001 agctagcaat aatgttaata aagctaaaaa gacagtaaca gcaaggttga aagctacaga
    12061 taatgcgagt tctactgtta acaaagttaa taataagata aaagaagttg ctaagcctgt
    12121 acctcctgta atcatacgag gacaagatga atctagttct ataatagata aagtaaaagc
    12181 taagattcag aatctaaaag ctgatactat cataaaaata aaatcacaag ctgatgaagc
    12241 tataaatact atttctcgaa ctaaaaataa attacaagaa tttgtgagta agagatatga
    12301 agcagcagtt aagattagag atgaagctag ttcagcactt agagggctta caggaaaaat
    12361 agattctttt gtaagtggag ctattagtaa attcgctaga ctggctacta ccgcaggagc
    12421 tttaataggt ggaattggtg taggttctgc tgtaaaagga tttgctactt ttgaacaaag
    12481 tatgaagaat acacaagccg taagtggagc aacaggaaaa gaaatggaag ctttaactgc
    12541 aaaagctaga cagcttggga gagaaactag ttttacagct aaagatgcag gagacgcaat
    12601 gtattacatg ggtatggcag gatggaagtc cgagcaaatg ataaaagcaa ttcctgacgt
    12661 tcttaacttg gcagcagcag gaggaacaga cttagcgtta acgagtgaca ttgtgactga
    12721 tggactaact gcattaggaa tgactgcaaa tgacacaact gaatttgttg atgtgatggc
    12781 agcaacaata actaattcaa atacaagtgt tgagttaatg ggtgaaacat ttaaatacgt
    12841 aggctctatg ggcggagcat taggagtatc tatgaaagat ttatctcttg cgacaggtct
    12901 aatggctagt gcaagtgtca agggaagtat ggcaggtact tcgttaagag gaggtctagt
    12961 tagattaata aagccaccag aagaagccgc atctgcaatt aaaaaatatg gaatagaatt
    13021 aaagaaaaat aaaaatggaa gtttagactt ggcaggaaca ataggaagtc ttagagagaa
    13081 attaggagga ttaaaagatg ttgaaaaagg tgttgcaata tcctctatat ttggtcgtac
    13141 tgcaatggca ggttgggcgg ctgtagtaaa tgctagtgaa agtgacttta ataagttaac
    13201 tacagctatt gcagaaagtg aaggagaagc taagagaatt gctgatatga agttagatac
    13261 cttatcagga caatttgaaa ttttaaaaag tgctattgat gatgtaagga taagtgtagg
    13321 tcaaagacta ggacctatga caagaggatt tgtagaagat ttaattaaga aaatgccaca
    13381 aatcggtgat gctatagttg gagtagtaga aaagtttgtt aataatttcg ataaaataaa
    13441 agcaggattt caagtattat tgcctgcaat tggttccgtt atagcctctg ttatggtact
    13501 taaagccaca tttgcttttg gaggagccat taaaagttta agtttacttg caagtacttt
    13561 tggtacggct aaattagttg ccttcggatt aacagttgga ataggggcta ttgttatagc
    13621 ttttgcagga atgactgttg ctatttctaa taataaaact gctatgatgg acttacaaac
    13681 acgttttggt tcgtttggtg agtatgttac tacaataatg gagactgttg gtggagtcat
    13741 aaagcttacg ttaggtaact tgcttataat gttaggtgga attggaaaag gaataggaat
    13801 acttttatct gataagagct gggatgaaaa agcttcatca cttaaaaatc tatttggcaa
    13861 aacaacagca gaaattaaaa caaatacaaa agaagcttta tcagatataa atggagaaac
    13921 ttctaatgca acagctctat taaaaaagtc tacttcaaaa gagttacaag gtgttactaa
    13981 agctttctca acagcatttg accaatctaa aaatgtaaca gagaagaaat ctagcgatat
    14041 agctagagca ttaacaaatg gattaaaggg tttagatgac caatctctta ctatgatgag
    14101 aggtttgaat gacaatatgg cgataatttt atctggtgtg acagcagata tgaaacctag
    14161 tgacaaagtt aataaaatca ccaaaaatct tgatgatgct ttcaaagcag gtaaattaag
    14221 tgcacaagaa tacagaagta gcatacaaga gactttaaat tttataagca agtatagtgc
    14281 agattcttca aataatttga aacaaggtat gagtgatgct ttcaatgcct tcaaggaagg
    14341 gacaaatata ggcggattaa aagacggagt aacaggaatg ttgaactctt taaaagcaac
    14401 tggtccacaa gctttagaaa ccttaaaagg tttaggagga aaagcaagtg agattttcaa
    14461 aggagtggat tttaattctt ctatagatgc acagaaaact aaagtattac agaatttaaa
    14521 tagtttagga ttagaaggaa cacaggctat agatacttta agaactattt tctcacaagc
    14581 atcatctgct ttggatacta caaatttaaa gcaaggttta agcaatacat ttaactcttt
    14641 taaagaagga tttaatagtg gaggaataaa aaacgctata aatagtatgc ttggaactat
    14701 taaccaagca ggtccacaaa tgcaacaagc attaggcaaa atggatggaa agatggggca
    14761 agtatttgct aatgtagact ttagtactcc aatagaaaca caagctagta aagttcttga
    14821 aaatttgaat aatctaggaa tagaaggacc aaaagcttta gaaactgtaa gaagtatatt
    14881 tgctcaagct tcaagtcaaa tacaaggttc agcttctcaa acggcacaac aagcgaatca
    14941 agaagtggct aatgctctaa ctcaaggtaa tccagctgta caacaagcag gacaacaatt
    15001 aggtacagat ttgactaatg gtgtagtaaa tggagtacag gcaggagtgc cagttgtaca
    15061 gcaaaaaagt aatgaacttg ctacagcaac acaaaacgga gtaacaaatg ctgtaaatag
    15121 tgcaactcct caaatagata attcaaatct tacaagtggt atagatacag cattcaatca
    15181 agctactgca acagttcagc aaggggcgag tagtatgtat aatggtgcta aacaaagttt
    15241 tacacaacta gcacaaatag gtagagaagc aggttcaagt ctttataatg gtgctacaac
    15301 ttcttttaat atgttagcaa caaatgttag agttgcatgt agtagcatgt acaatggagc
    15361 tagaacatct tttacgagtt taagcagttc agctataagt gccatttctg ctatgtgtag
    15421 ttctgtagta agccaagtta gtgccatgtc gagtcaaatt atcagctatt ggaatagtgt
    15481 aagagcaaca gtttcagcac caattacagc atcttttaat gttaagacta ctcaaacaac
    15541 agttaaaaga accgtaaatg aaagtagtgg tggaatactg ggtaatatac tagaccgttt
    15601 tgctgatggt ggagtagcaa caagaacttc tatctgcgga gagaatggag ctgaaatggt
    15661 tatccctctt acaaacacta gaagaagtag agcaatagaa ttatatgaac aaacaggtaa
    15721 aatgttagga ttaggttcaa ctccttctca aaaagtaggt aattctaata ttgtaaataa
    15781 tgttagacaa tttcctcttg caaatgtttt agatacagat aataaagaat ataaagaagc
    15841 tacaccaaac agtgttaatt cttctaataa tactataaat ttaggcggaa tatctataaa
    15901 tgttcaaaat agtgataaca aagaagaaat gatacaagaa ctattatctc aagtagaaag
    15961 tggaataaga gaagcattac aagatattgg ataatgtcga attgttgcta aaaaaatctt
    16021 cctcataaat gatataatat tgttaaaata tgcaaattta tgagggggaa attttatgtg
    16081 gcagaaattt aaaagtatga atggaatttt aaaaattatt attggaatta tagctataat
    16141 tcttttacca ataacattgg ttttgttatc tattgagttt ttagttaaag ctattggaag
    16201 taagaaaaaa gctaaaattg cattaggttg catattagtt tttttgacaa cactttgtac
    16261 tagaaatgtt tataatgtac taagtataga gaaagaagag catattcctg tgaagcaagt
    16321 ttcttataat gataaagata agggaaaatc cgagaataat attcaagaac aacaacaaaa
    16381 gaaagaagaa tcaaaaaaat tggaagaaca aaaaaagaat gaagaaaaag agcaaaacaa
    16441 tgaaccaaca aagtttttta ctgatgtata tttaaaaaat aaaaattgtg ttaatatgac
    16501 atcttatgaa ggtataaagt caaacctaga tatattcggt tataaatatg aagttataga
    16561 gccgaatgaa actacattaa gacagattaa tgtatatgat aaccaaagta atgataccat
    16621 tcaatttcaa ttttatgaaa atgatactgg agaagaagtt gtaacagtta tgcaatacaa
    16681 taaaaaagat gaacccgaca aatctgttgc aataagtgat ggtttccata cacaaccacc
    16741 aaaatttcag aatcatatta ataatacaaa taaggaagtt aatagcatag aagaacaaat
    16801 aaattttatg tttaattaat atttgtataa tactttaaag ctcttacagt ttgtaggagc
    16861 tttttattgt aaaaaagagg tgataacttg gtaatagata tttatctaaa aaatgaaaaa
    16921 gaaaaaatag attttcattt tccagtaaat ccacaagatt ctttatctat aaaaaaagaa
    16981 aaaaggtttg aaactgtaga tatagtaaac ttaggtgaat ttgatataaa aaaagaaggg
    17041 gagaagataa gagaaatatc atttaaaaca tttctgccta acttatatga cgcttcttat
    17101 tgcagataca gcgagttaaa aaatccaatc gaagtagtgg caatgcttga aaaatgggta
    17161 gaccaagccg aacctttaag acttattata actggttttg gctacaatgg attagtcaca
    17221 atatctagtt ttagcaatac tcaaacagca ggaagagaag aagatagaga tattgagata
    17281 acatttagaa cttacagaga actgaagata gagacattaa aaaaagatac aaaaagtaat
    17341 actaaaacag atttaaaaga taatagacct aatacccaaa ctaaatctaa aatatatact
    17401 gttaaagcaa gtgatacatt atataagata gctaaaaatc ttttaggtaa gggttcaagg
    17461 tggccagaga tttataatat acccgaaaac aaaaaagtca ttggtaaaaa tcctaatata
    17521 attaaaaaag gtcaaaagtt ggtgatacct agtaaatgaa aataatatta aacgggaaat
    17581 atgatattgc aaatttcaat gaaggaataa ctctttcaga agctatagac ggagttgcat
    17641 ataagatgga tgtatcatta gtagaaccta aacaacttaa agatataaat attaaaaaag
    17701 gtgataaaat aattctaatt gatatagcat atgagagtaa aaaagaagag acaatatttg
    17761 atggagttgt atgggaaact agaaggagtg aaaagagtaa gaaactaaca ttgtcttgca
    17821 gagaaagaac agtttacatg gaagaatcag aggaacaata tcagtttaaa gaaaatacag
    17881 caacacagag aattgaatat tactgtaagc aatggaatat accctattac aacttagcta
    17941 atacagggaa gaaacttgct aaagtaatac ataagacaaa tatactagat atgataaaaa
    18001 aggacttaaa agaaacagca acaaaaggtg gagacttatt tagagtaagg atggataata
    18061 aattaaaatt attcaagctt ggtactaatg caaatgtata taaattagat agtatattag
    18121 aagatgctaa ctttacaagt agttttaatg atgcagtaac aagtgtaaaa gttttaggta
    18181 agagtaaaga cgaaaataca aaagcgccta taattgggac atataaaaaa gatgctgata
    18241 agtttggaac actacaaaag attaaacaag atgaaaagat aaaaaatgct aaagaagcta
    18301 agaaagcagc agaagcaatg ttcaatagtg gagaggaaac aataagtgta gattgtgcag
    18361 tagatataaa tagaataaga gcaggtgaca aagtaagttt aaaaagtaaa gaatattatg
    18421 ttatagatgt cactcataca ctagattcta gaccgaaaat gaagctgaat atagggtctt
    18481 tagaatatat aaggaggaaa ttttataata atgactgatg ctagatttaa tggaattgct
    18541 agaatattga aagaaaatat gaataaaagt gtagcaaatg gcacttttgg aatgggttgt
    18601 gaacttgcag aaataacagc aaatggatta aaagtaaatg gctataaaga tgaaatacag
    18661 gactatctag tattagagaa tttaacatta aaagaagatt attttacttt ttcagatgaa
    18721 gctttaagtg gagaatatag acataagcat aaaatagaaa ctccaaagga attgaagcca
    18781 ctacgtatag gcgataatgt gctagtagct gttatgggag ctgaatttgt agtaattggg
    18841 agggttgtaa atgccaaacc tatttcctca aagtgaaact tttgaaactg tagaattaaa
    18901 aaataatgat gaaaatgaat tggacctaaa gggttctttt ttatttgatt ttgaaaaagg
    18961 tgaatttgtt aaaaacgcag atggaacact aaaaaaatgt gataaggtgc aggcgtacaa
    19021 acaatggtgt caaaaggcta tattaacacc tagatacaaa aaagcagctt atacaaacat
    19081 ttatggaagt gaaataaaag acttaatagc tagtaactta tctcaaagtg caaaagagct
    19141 tgaaataact agattaataa aagaaactat tttggttcat ccttacacaa aagaagtagg
    19201 agagtttagc tttaattggt tggagaatag caggttagta gagtatgaat ttgatgtact
    19261 aacaatagat gatgaaaata tagtaattga tggcaatata aaaaggtagg tgattatatg
    19321 gaaagagagc tacctatacc agtattttta acagaagatg aggactctgt acatgaaagg
    19381 atgttaagca actttcaaga tgtttctaca ttagaaggtg acttcatcta tgatgcaaca
    19441 agacctacag cagagcagat agctgaatta aaacaactag gattacaaaa taatttaaag
    19501 atagcatttc ctcagacttc ttatggaact tatttagagt ggcttggtga atgtaaagga
    19561 gtatttaaaa atcaaccaac taaggctact ggagttatta catttacagg tgtacaagga
    19621 actatcatta caaaaggaac tatagtaact actattgcaa ctgatgaaaa acagagcata
    19681 gaatttgagc ttcttgaaac caaaactata ggagaaaatg aaacagtaga tattaaagca
    19741 gaaagtagga ttgtaggaac tatagggaat gtgtctaaag gtagtatatc cgttttacta
    19801 ggttctatta gtggtgttaa atcaattact aataaagaag atttcagagg tggaacagat
    19861 atagaagatg aagaacattt tagagaaaga gttcttgtag cagagcaaga agataaactt
    19921 agtggagcta gttcagatta tattcgttgg gctaaagaag ttgatggagt tggatatgct
    19981 tatgtagttt cagaatgggc tggagcaggg acagtaaaag tattaatact agataaaaac
    20041 agaaaagcag caacacaaga attaatagat aaggtccaag aatatatata tccattgaat
    20101 atatcagaag gagaaaatag agatgggaaa gctcctatcg gtgcattagt tacagttgtg
    20161 acacctgaca cattacttat taatgtaaaa gctagtttta tatttagtaa tggctttagt
    20221 gaagaaactg tattaaacaa tctaaaaact aagatagata aatatttaga taagattgat
    20281 ttagggggga cagtctcata caatgctata caggcgatag taggctctat gatgctgaca
    20341 gatgaaggta tagaagactt ttctaatctt actataaatg atgtaaaaga aaatataaaa
    20401 ttgcaagacc aagtggtcgg aataggggaa atagttaacg aggtggttgg atgatagctt
    20461 ctaaaaaagg taaagaaatg cttcttacat tatctcctat ttatgaacaa tctatcataa
    20521 tgcaaagctt atatgaagct ataggaagcg aatttgataa tctagagtta ttggatgaag
    20581 aaatagaatt acaattattc cctcagagtg caacatgggg tttgggcttt tgggaaaata
    20641 gagtagggtt gattactaac ttagatgaag atatggaaac tagaagaaga aaagtaattg
    20701 ctaaacttca aagtaaatat atcatgacgc ctaaaagaat gtctatgata ctccaatctt
    20761 atacaggtgc aaacataaaa ataaatgaaa atatatctcc atatactttt ggtgttgaat
    20821 taaccagtac ccaaggtttt cctaaagatt tagaagattt atataagaga gtaaatgtta
    20881 taaaaccttc tcatttagct gtaagttata agttagtttc tttattgaaa agtaaaacct
    20941 attttgcaca aacagcaatt atgagcgaag aaataactat atatccgtac acaagcaaag
    21001 aagtaaaagc aagtgttaaa gccaagtttg cactagctca taacatgagt tcagaaacat
    21061 taacagtgta tccaagatag gaggtggtat aaatggctga tgaacaattt tacacgatac
    21121 taacaaatat aggtaaagct aagattgcta atgcaggaat gttaggtaag ccagtagttt
    21181 tagagaagat tcaagcagga gatggtggag gaaattatta taatccaaca gaagaacaaa
    21241 cagcattaaa aaataaagtt tgggaaggga atataaatgc ttttgataat gatgaaaata
    21301 atcctaactg gattattgca acagcatgta tccctggttc gataggcgga tttacagtta
    21361 gagaaatggg tcttatagat aatgaaggag atatgattgc aatttgcaaa agccccgaaa
    21421 cttacaagcc aaaaattgat aatggagcta tgaaagattt gtatttgaaa tttatcatag
    21481 aagtatctaa tgtagagaaa gtgacattag ttgttgaccc tacagctatt tttctaacta
    21541 aaaaagatga agaaaaaata ttaacaaata ttaataaact agacactaaa atagatacaa
    21601 ccaaaataga attaacaagc aac
//
LOCUS       DAJMZY010000072        21534 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.072, whole genome shotgun sequence.
ACCESSION   DAJMZY010000072 DAJMZY010000000
VERSION     DAJMZY010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 21534)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21534)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21534
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.072"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            complement(<1..790)
                     /locus_tag="OE968_002527"
     CDS             complement(<1..790)
                     /locus_tag="OE968_002527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp11"
                     /protein_id="HCP7219802.1"
                     /translation="MKMNKKILSLGLAVSLILVNFKSVNASSVVEKIYGKDRYETAAK
                     IADKQTYETVILVNTEKSLADGLSASGLSGATKAPILFTQQNKIPADTNRCLKNIKKA
                     YIIGTEDTISKSVEKELDSKNIEVKRIGGEDRLKTSYLIAKEIATIKKVDKVLLTNAY
                     SGEADAMSVSSVATRDGAPIILTDGKSVPFDVKNIQSYCIGSEEIMSNPLVKNTNSVR
                     IEGTDRFETNKNVIDYFFNSADGFYVSDGYQLVDAIAAAPLTKNS"
     gene            complement(1157..3037)
                     /locus_tag="OE968_002528"
     CDS             complement(1157..3037)
                     /locus_tag="OE968_002528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp10"
                     /protein_id="HCP7219803.1"
                     /translation="MSKRKSFIRTIAVSTMAVAVTGSATCAYAAPVLQGTKTYEKVNT
                     IDISVDSVENIVYSFQASIKVQGEVEVVDNEQKEKITWSDNIKSQIKSGNANATCRVE
                     YNKSSNTTTLDIYVTSNEDLLDGNRLNIGRISVKKSGSNSNADYKVLGKGTNDKPALK
                     IVTYNNKTVDYENISSDEGLIFTLINESEVKPIGGTGSSKNDPEKYKVEKSEALEYLL
                     NNIRINYSIVSKETQESGSNVILKLGLAQKTTKGRKATINKYVEVTLPKSLEYIVENE
                     LSKPDELPPDNGNGGNNGGGSNSGGSSSGGSSGGGSSSDSTSNVTVKKLKGADRFETA
                     IKISQSGWTKSDTVVIVNGEDKSMVDGLTATPLASVKNSPILLSSNEKLPQKTVEELK
                     RLNPSKVIVIGGNNSMPNSVVEAIKAVNSKISVQRIGGDTRYQTSINIAKEIDKTNNV
                     SKLYIGAGNGEADSLSIASLAGKEKTPIVLTQKDGVDNEAEQFIKSNKVSNIYFIGGV
                     EKISNKAIEQVGKIANKDISNNRVAGQTRQETNAKVIDKFYSQSKLDGVVVANQDKLI
                     DALAVGPLAAKNNSPVILATNTLDKSQESSLKGKNSSKLFEVGGGIASSVIDKIKSLI
                     EK"
     gene            complement(3241..9204)
                     /locus_tag="OE968_002529"
     CDS             complement(3241..9204)
                     /locus_tag="OE968_002529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium-binding adhesion protein"
                     /protein_id="HCP7219804.1"
                     /translation="MKKAISCVLAVSMCSAPLNVFAEPILEGKLRAVEKSVTEKLRGS
                     LEVDLNFSLPIKNSESESMTNMQLRLKDDSNNSGIIKLGEKDSGTVNVGTDNIEYTIK
                     KLSASRSEIKNKDENISYYNIVFNNLPVGKYNVEVSGDGFKNKEIKDIDISSYSQRVL
                     LSNRASVDNKNKPLNYELFLMGDVNGDGKVDKSDYNKVLENIDSNKREFDLNRDGKVD
                     IVDLDYVQKNLGQSEDAKSLESIVSTNPIVDTSKVELKGNSDVDINGNVENLFSGENN
                     GVTISSKNDEISEEKPAVMDIALSEALNMEVINIKAPEGTAPAKGIVEVTDKDGNVQQ
                     IPYENKEYMKNLKDEEQQEEVNNEQEEVNQEEVNNKDENINQTDNNSNNKDENNDKQQ
                     ENSDKQEANSNTNQDKNNDKENSSMDKPNSDEDTPKEEGNISKDDNSTTSTYSRSALE
                     TYADVQNSDIVINLGKQVAVKKITIKITATTANDRNLAEISKVEFLNNVYKEIPKPEM
                     NIPKINKISTSTAVGNEKVSFYWNNEVNVSAYELILDKIDSKGKVLSTKKLQTSKNTI
                     EVRDIEAYGLYRVSIQSLNGDWSSGYKDATPENLDGVPENVDSNYKPIQFSPDSILEF
                     QVVPDTKPEPPEGINVKGKFKSLDVSWKNHKQAKDFDLYYKEKGSNGSWIKYNDKLIR
                     GTSSKIEGLKDNTTYEVRMTATNHLGTSGMSKTYIGTTESMDAPTTPNYRLINTPKEN
                     GGFGIPTNHIVDVVYPDGYDKSEYSDKNPFDKFNVVDGDFTTHWTFPTYNAAEGTNRG
                     PIITFDKSYTMDTFMATPRFDVSDKTINDFEVRYWDENGQLHNLGDVPFETKTDPVNN
                     NKYVMVRLKEPITATKIQVSVCSSYSYKSNISELKFYEYDSIEDDVRNLFMDGLQVEL
                     KEDVTQEKITELKDRLNTPDKASGEYHPYKTVIERELKLAQDLYNDRATLTDVTTVNQ
                     EINKLGKYKDKNGQYTVNSNNLGMQNDWQALGVAARAGDEITVYVGSKSGKTPKLIYT
                     QYYGESGAYKSGEINLNTGKNVIQLSKLHSLDIECGGSLYIRYAEDTPSGGDIKVRVA
                     GATKIPHLNLNGTINDKSPAGVSESKKKIKAYIEELAKYKDAVKGEPYYPGTNVGNSY
                     GYSEKTGVLNTTDIESDKVTLNVPATAVYQEISKGNSDLNTQVDRLYNSMLAWEQIMD
                     LVYSERGVFKTQDLDGNGTVDDNEFNLTKNDMAPKSRMNIKYQRMFIGAFMYASGLHV
                     GVEYGSVPGLMNGVPFQIDDSGKATGGNLFGWGIGHEIGHVTDIGKMTYSETSNNVLA
                     LLAQTFDDKTHSRLEGSTMDKIYEHVTSNSLGIPSNVFERLGMLWQLHLAYDDDFTGS
                     MLKNNSDADLSNDTFYAKISRKYRALSSSDPINSLPKDQMLVAMASSVVEKDLRDYFK
                     AWGVEITPELNSIMDSKNYEKESRKIQYVNDEARRKILNENIASMAKDTKVSASFSDG
                     IQSGSLVKSNKISIDLDVDKDKDKILGYEIIRSDGNYLDGENGTQVKYRTVGFVDAKG
                     NSKTKFTDNISPLNNRAFTYKVVAYDYHLNPTEEFEVGTVKLSDEGKINKSAWSFITN
                     TVSDGDVRTENDSHGPLQNPEIDNIKDNDASTTYKGKIISKAEWNKDPQKDPDINVEE
                     NPYIIVDMKETLPIVGLKYTKPETEARKFSLKGLFNFRKNTSTTYNPLTNYKIQVSND
                     KKNWEDVSQGTFEYGQDLVGGGKDQDNEARVTFNKDGKLWTYQARYVKLISNNKSNIE
                     VAELDIIGPPGDNIEIGIINNADETRTNGIGKLAEDYVYQSDDSSTSEDETGKIPAGS
                     IVITGEYSGNPAFNLPLLIDKNNKTISGEALLFAEVPEKGELGEISKGTWVYYMPKEN
                     FDSLSDKVKAELYRYNDLQGDTPVGQRFVSDTMYVPVGAKNYDELKTISLTDSNSKAR
                     KATRNSIDISNKKVITVSNKVKGNIVRDK"
     regulatory      complement(9328..9413)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            complement(9585..10988)
                     /locus_tag="OE968_002530"
     CDS             complement(9585..10988)
                     /locus_tag="OE968_002530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp9"
                     /protein_id="HCP7219805.1"
                     /translation="MKNSKKILAIGLTLFLVMVNTPMVNALTSVEQIKGNDRYETAAK
                     IADKQNYNTAILINSDNSLADGLSASGLAGALNAPILMTKQNQIPNTTMERLNKAKTV
                     YIIGSESTISKNVENQLLSKKKVVQRIFGENRFDTSIKIAEKIKEIKPIDKVIIANGF
                     TGEADAISASPVAARDGVPIILTDGNSVGFDTTGLKSYALGSSEIISDELVKSTNSIR
                     LGGTDRFETNKIVIQEFYKNSKEFYLSKGLQLTDALAASTIAKNAPVVLVENGSNKSI
                     LSGADKLTVLGGINQNVIKQCINQASPNQQGLYYNPNDRAFKERIKGKVYALTKQYRK
                     ENGVRALSVASRLEGLANDWSNLMANKKTLSHTINGKNSYSTFLKYLDWSEIKPGYIA
                     VQGENIIKYKIPDKPVYTNRDADDIGNFIFNEWKTNPEEGTNMLHKGYEIMGFGIAIT
                     GDKNLYATHEFYGRYKE"
     gene            complement(11450..13345)
                     /locus_tag="OE968_002531"
     CDS             complement(11450..13345)
                     /locus_tag="OE968_002531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp8"
                     /protein_id="HCP7219806.1"
                     /translation="MLSNKKRSMAIVMAGATVMSAAAPIFADNTVTENVDKNYTVSAK
                     DSAKLIEEVRKALEVKFEDTKAGANVNDRVYDIKVDNVNLTNATQLQNKINSLTEGQS
                     LKVTIQDKGHQVLGGKVVDYKIENYKTAQEIVDAVNAYNATLAEDSDNKLTATIKSTN
                     TVEVKRAKDSANVITLNVGDQHLDFSKVITSEEGTFEGYEKSYSDIDSKELHTITVKN
                     ADLQDISAEELFDGIRLTTLGREIVNKVKNGYALTFENEAILTQEQEDSDDKDKPEKS
                     SFDIVLSKANEKPETISVSSKNHKLVRDLHKVLTDVKDGKELKVEVLSGDSRFTTAVE
                     VSKERFKDGEAEAIILVGEDAIVDGLASAPLASQKNAPILLSKKDSLPSEIEAEILRV
                     LGSNLSSKKIYIVGGESKVSKETEEKLSKLGVSKVERVSGEDRFETSLEIAKQLKDTF
                     KTAFVVGGNGEADAMSISARAAQFGAPIIVTGNELDANAEKLLKGKELEIVGGENSVS
                     KEVEDKLVDIDLNNKVERLAGENRKDTNAKVINKYYAGATKAYVAKDGYVGGNGQLVD
                     ALTAAPLAASSKAPIVLTTEELSKSQEEVVELRLKNATKLVQIGEGIAKNAIEKIAEK
                     INLFTKN"
     gene            complement(13972..14115)
                     /gene="scfA"
                     /locus_tag="OE968_002532"
     CDS             complement(13972..14115)
                     /gene="scfA"
                     /locus_tag="OE968_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="six-cysteine ranthipeptide SCIFF"
                     /protein_id="HCP7219807.1"
                     /translation="MENKHVKTLSQATLKQSAAKGGCGECQTSCQSACKTSCTVANQE
                     CER"
     gene            complement(14181..14543)
                     /locus_tag="OE968_002533"
     CDS             complement(14181..14543)
                     /locus_tag="OE968_002533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04086 family membrane protein"
                     /protein_id="HCP7219808.1"
                     /translation="MGKSNYIFKGLGYAYIITLAVLLVYNLFLTFTDIGGDNITMVSS
                     FITTISAAIGGFYTSKHMKEKGLMYGLLVGLLYIVCIFLTVFLAQEKFVFEIGMIYKL
                     LLISAAGGIGGVLGVNFK"
     gene            complement(14601..14894)
                     /gene="yajC"
                     /locus_tag="OE968_002534"
     CDS             complement(14601..14894)
                     /gene="yajC"
                     /locus_tag="OE968_002534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HCP7219809.1"
                     /translation="MPQQQIIMSIGLWVVVIAIFYFLMIRPQKKKDKQLKEMRSSLSV
                     GDKVITIGGIVANVAKVEDDVVILELGPNRTKVPFEKWAIGTVKSKKEEIEED"
     gene            complement(15028..16149)
                     /gene="tgt"
                     /locus_tag="OE968_002535"
     CDS             complement(15028..16149)
                     /gene="tgt"
                     /locus_tag="OE968_002535"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HCP7219810.1"
                     /translation="MYAVRYELIKTCKQSGARLGRLHTPHGIIETPIFMPVGTQATVK
                     SMTPEELKEIGSQIILSNTYHLYMRPGHELIKRAGGLHKFMNWDKPILTDSGGFQVFS
                     LGPLRKIKEEGVEFRSHLDGSKHFLTPEKAMEIQNALGSDIMMAFDECAPYPSDREYV
                     KNSLERTTRWLKRCKDAHNNTDKQALFGIIQGGMYKDLREQSAKEITNIDLPGYAIGG
                     LSVGEPKPLMYDVLEHTTPLMPKDKPRYLMGVGSPDDLVEGVIRGVDMFDCVLPTRIA
                     RNGTAMTSQGKVVVRNATYAEDFTPLDPECDCYACKNYSRAYIRHLIKANEILGARLI
                     TTHNLHFLLNLMKQIRQAIMEDRLLDFRNEFFAKYGYEI"
     gene            complement(16228..16713)
                     /locus_tag="OE968_002536"
     CDS             complement(16228..16713)
                     /locus_tag="OE968_002536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219811.1"
                     /translation="MHSLQKQKKNNPILKIAFIFERVLAVVVLIAVFLGTIDVLRLMW
                     GAYIVDFQNPVQYSQLNDFLAQILLLVIGVELVVMLSLHIPGAFIEALLYAIARKMLL
                     LPKNEGMIDVLIGVIAIAGLFAIKKFLVTKDKSALNIMSIHDEEAIKEQQNKEDEDKS
                     I"
     gene            complement(16725..17750)
                     /gene="queA"
                     /locus_tag="OE968_002537"
     CDS             complement(16725..17750)
                     /gene="queA"
                     /locus_tag="OE968_002537"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HCP7219812.1"
                     /translation="MKTSDFKFDLPQELIAQVPIEDRASSRLMVLDKETGNIEHKVFR
                     DIIEYLNPGDCLVLNNTRVIPARLIGEKLETGGKIEFLLLKRTEEDTWQALVKPGKRA
                     KVGTKFSFGNGKLIGEVVDLSDEGSRIIKFHYDGIFEEILDELGNMPLPPYITARLDE
                     KERYQTVYSKHNGSAAAPTAGLHFTEELLNKIKEKGVDIAFVTLHVGLGTFRPVKVED
                     VLNHKMHSEYYMVSQEAADKINRAKENGKNVICVGTTSCRTIESACNEYGKMKETSGW
                     TEIFIYPGYKFKVLDKLITNFHLPESTLIMLVSAICGKDNVLNAYNEAVKERYRFFSF
                     GDAMIIK"
     gene            complement(18068..19087)
                     /gene="ruvB"
                     /locus_tag="OE968_002538"
     CDS             complement(18068..19087)
                     /gene="ruvB"
                     /locus_tag="OE968_002538"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HCP7219813.1"
                     /translation="MQGFEDENRIITSTMKMEDIDIENSLRPKTLEDYLGQEKSKEQL
                     SIFIEAAKSRNEQLDHVLLYGPPGLGKTTLASIIANEMGVNLRITSGPAIERAGDLAA
                     ILTNLNENDVLFIDEIHRINRSVEEVLYPAMEDFCLDIIIGKGPSARSIRLDLPKFTL
                     IGATTRAGMLTNPLRDRFGVICKLDYYTVDELSKIVLRSSSILDAEIQSNGALELAKR
                     SRGTPRIANRLLKRVRDFAQVRADGKITDKVAKDALELLGVDSLGLDFVDEKLLMTII
                     EKFRGGPVGLDTLAASIGEDRNTIEDVYEPYLLQLGFINRGPRGRVAMPLAYEHLKIP
                     YPNEK"
     gene            complement(19194..19796)
                     /gene="ruvA"
                     /locus_tag="OE968_002539"
     CDS             complement(19194..19796)
                     /gene="ruvA"
                     /locus_tag="OE968_002539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HCP7219814.1"
                     /translation="MYSYIKGTVEEIYIDSIVVENNGIGYKINVSSNTIMNLQVGEAT
                     KIYTKLIVREDDMSLCGFVSREELKMFELLTSVSKIGPKVALSILSFASPAQLGAYIL
                     SEDIGKLSKAPGVGKKTAERIVLELKDKVDKNNIEFEPTLLSQKPTLISQDESVDALV
                     ALGYTLSESKEAVQKCKKDGMNTEAIIKKALTYIMSKSLK"
     gene            complement(19789..20298)
                     /gene="ruvC"
                     /locus_tag="OE968_002540"
     CDS             complement(19789..20298)
                     /gene="ruvC"
                     /locus_tag="OE968_002540"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="crossover junction endodeoxyribonuclease RuvC"
                     /protein_id="HCP7219815.1"
                     /translation="MIILGIDPGIAIVGYGIIEYKNSKFKVIDYGAVTTPAHMNISRR
                     LELVYKGIDTIVKNYNIDEVGMEELFFNKNVKTAITVAQARGVTMLACAHNGKPVYEY
                     TPLQVKQGVVGYGRADKAQVQQMVTSFLSLKKVPKPDDVADALAVAICHAHSNKLEKT
                     LKNIGGKYV"
     gene            complement(20641..21270)
                     /locus_tag="OE968_002541"
     CDS             complement(20641..21270)
                     /locus_tag="OE968_002541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219816.1"
                     /translation="MFEKKKKELFPWKISALILVGVFVLSSGVYIGTRLKHNGVQTGE
                     VVSTSANMNEKSKEAFGLNKNCEVWLQSEGENETNYKRTLTMAGIVPESLLDKTKSEI
                     VSYFKKEYPTKKIKSMDKNEIILVESKYSDNKDVQAMDVTIKGKYTIENDNGNIALYK
                     YDDSGSKTLVEKTKIRVDSLPKTVQDEIKKGVVMDTEEEAYSRLEDFAS"
BASE COUNT         6226 a         3946 c         2377 g         8985 t
ORIGIN      
        1 gagagttttt agtaagtggt gcagctgcta ttgcatctac taattggtat ccatctgata
       61 catagaatcc atctgcacta ttaaaaaagt agtctattac gtttttgtta gtttcaaatc
      121 ggtcagttcc ttctattctt actgagtttg tatttttaac tagaggatta ctcattatct
      181 cctctgaacc tatacaatat gattgaatat tttttacatc aaaaggcaca ctctttccat
      241 ctgtaagtat gattggagct ccatctctag tagctactga tgatacactc attgcatctg
      301 cttctccact atatgcatta gttaatagta ctttatccac tttttttata gttgctattt
      361 ctttagctat taaatagctt gtttttagtc tatcttctcc accaattctt ttgacttcta
      421 tatttttaga atctagttct ttttctactg atttacttat agtatcttct gtacctatta
      481 tatatgcttt tttgatattt tttagacatc tatttgtgtc tgctggtatc ttattttgtt
      541 gtgtaaatag tattggagct tttgtagctc ccgataatcc acttgcactt aatccatctg
      601 caagtgattt ttctgtattt actaaaatta ctgtttcata agtctgttta tcagctatct
      661 ttgctgctgt ttcatatcta tctttaccgt atattttttc tactactgat gatgcattta
      721 cacttttgaa gtttactaag attaatgata ctgctagacc taatgataat atttttttgt
      781 tcattttcat atccccctga tgatttttat attttatatt tatattgtga ttattttcca
      841 tttattttct ctttattttc catatattat agagtatata tgatatgaat atatctcgtc
      901 tatatattag tgttttattt tattaaattt aaaaaattat ttttaacttc tttttaaaca
      961 tattcaaaat tgaatttata tttatatata taaaagatat ctgctttatt taaaattaaa
     1021 cttaatatag ctcaaattat tatacatttt aacctcaata ttattagatt gttaagataa
     1081 tgaaaataaa ataagaatgc atttaaatat ataactttat atctaaatac attcttattt
     1141 tctatttact taatatttat ttttcaatta aactcttaat cttgtctatt acagatgagg
     1201 ctattcctcc acctacttca aacaactttg atgaattttt accttttaat gacgattctt
     1261 gtgatttatc taacgtattt gtagcaagta taactggtga attgttttta gctgctaatg
     1321 gtccaactgc taaagcatct ataagtttat cttgatttgc aactacaact ccatctagct
     1381 tagattgaga gtagaattta tctattactt tggcattcgt ctcttgtcta gtttgacctg
     1441 ccaccctatt gtttgatata tctttgtttg ctatttttcc aacttgttca atagccttgt
     1501 tagatatttt ttctactcca ccaataaaat atatatttga caccttattt gatttaataa
     1561 attgttcagc ttcattatct acaccatctt tttgtgtaag tactattgga gttttttctt
     1621 taccagccag tgatgctatt gataatgaat cagcttctcc atttcctgct cctatataca
     1681 acttgcttac attattcgtc ttatctattt cttttgctat attaatagaa gtttgatatc
     1741 ttgtatctcc acctattctt tgtactgata tttttgaatt tacagctttg atagcttcaa
     1801 caactgaatt tggcattgag ttgtttccac ctatcacaat tacttttgat ggatttagcc
     1861 ttttcaattc ttctacagtt ttttgaggaa gcttttcatt tgatgataaa agaattggtg
     1921 agttttttac actagcaagt ggtgtagctg taagcccatc caccatactt ttatcttctc
     1981 catttactat tacaactgta tctgattttg tccaaccact ttgagatatt ttgatagctg
     2041 tctcaaatct atcagcacct tttaattttt tgactgtgac attagatgta gaatcacttg
     2101 aacttcctcc tccagagctt ccaccactag atgagccgcc tgaattactt cctccaccat
     2161 tatttccacc attgccatta tctggtggta attcatccgg ttttgataat tcattttcaa
     2221 ctatgtattc taaacttttt ggaagtgtaa cttcaacata tttgtttatt gtagcttttc
     2281 ttcccttagt tgttttttgt gctaatccaa gttttaatat tacatttgaa ccactttctt
     2341 gtgtttcttt actaacaata gaatagttta tcctaatatt gtttaataaa tattcaagtg
     2401 cttcactttt ctctacctta tacttttcag ggtcattttt actagaacca gttccaccaa
     2461 ttggttttac ttcactctca ttaataaggg taaatattaa tccttcatca gagcttatat
     2521 tttcataatc cactgttttg ttgttatatg ttacaatttt taaagctggt ttatcatttg
     2581 ttccttttcc taaaacttta tagtcagcat ttgagttact gccagatttt tttacagata
     2641 ttcttcctat attcaatcta tttccgtcta gtaaatcttc atttgatgta acatatatat
     2701 ctaatgtagt tgtattactt gatttgttgt attctactct acaagtagca tttgcatttc
     2761 cactttttat ctgagatttt atattatcag accaagtaat cttttctttc tgctcattat
     2821 ctactacttc aacctcacct tgtactttta tactggcttg aaatgaatat actatgtttt
     2881 ctactgagtc cacagatata tctatagtat ttactttctc atacgttttt gttccttgta
     2941 aaactggagc tgcatatgca catgtagcac taccagttac agctactgcc atagttgata
     3001 ctgctatagt tcttataaaa gattttcttt tactcattaa cacccgtcct tatctatcat
     3061 taactaagtg gataaattta cttatccacc tagcttttat atttaattta taaattaccc
     3121 taaatttatg gttacattta tatactttac ttttaatatc tactatttta aaactattct
     3181 agtacctaat cttattagat atacaatgtt agtattttta cgtttttaga gttccaccta
     3241 ctatttatct ctaacaatat taccctttac tttattgctt acagttataa ccttcttatt
     3301 actgatatca atagaatttc ttgtagcttt tctagcttta ctattactat cagtaagact
     3361 tattgtcttt aactcatcat aattcttagc tcctacaggt acatacattg tatcacttac
     3421 aaatctttga cctactggag tatctccttg aaggtcattg tatctatata gttcagcctt
     3481 aaccttatca cttaaagaat caaagttttc ttttggcata tagtaaaccc atgtaccttt
     3541 actgatttca cctagttcac ctttttctgg aacttctgca aataaaagtg cttctccaga
     3601 tatagtctta ttgtttttat ctataagtag tggtaaatta aatgctggat ttccactgta
     3661 ttcacctgta ataactattg aacccgctgg aatcttacct gtttcatctt cacttgtgct
     3721 agagtcatca ctttgatata cataatcttc tgctaatttt ccaattccat tagtacgagt
     3781 ttcgtctgca ttatttatta tgccaatttc tatattatca cctggaggtc ctattatatc
     3841 taattctgca acttctatat tagacttatt atttgagatt agttttacat atctagcttg
     3901 gtatgtccaa agtttaccat ctttattaaa tgtaactcta gcttcattat cttggtcttt
     3961 tcctccacca actaaatctt gtccatattc aaaagttcct tgacttacat cttcccagtt
     4021 ctttttatca ttacttactt gtatcttgta attagttaaa ggattgtatg ttgtgctagt
     4081 attctttcta aagttaaata atccttttaa tgagaacttt ctagcttctg tctctggttt
     4141 tgtatatttt agtcctacta taggtaatgt ttctttcatg tctactatta tatatggatt
     4201 ttcttctaca tttatatcag ggtctttttg agggtctttg ttccactctg ctttacttat
     4261 tatctttcct ttatatgtag tacttgcatc attatctttt atattatcaa tttcaggatt
     4321 ttgtaatggt ccatgtgagt cattttcagt tctaacatca ccgtcagaaa cagtatttgt
     4381 tatgaatgac catgctgatt tatttatttt cccttcatct gataatttta cagtaccaac
     4441 ttcaaattct tctgttggat ttaggtgata atcatatgca actaccttat atgtaaatgc
     4501 tctgttatta agaggagata tattatcagt aaatttagtc ttgctatttc cttttgcatc
     4561 cacaaatcca actgttctgt attttacctg tgttccattt tcaccatcta aataatttcc
     4621 atcacttctt attatttcgt atcctagtat cttatcttta tccttatcta catctaggtc
     4681 tatagatatt ttattagatt taactagaga accactttgt attccatcag aaaaactagc
     4741 acttacttta gtatcttttg ccatactagc tatattttca tttaaaatct ttcttctagc
     4801 ttcatcattt acatattgta tctttcttga ttctttttcg tagttcttgc tatccattat
     4861 actgtttaat tctggtgtaa tttctactcc ccatgcctta aagtaatctc ttaaatcttt
     4921 ttcaacaaca cttgatgcca ttgctactag catttggtct tttggtaaac tattaattgg
     4981 gtcactactt gaaagtgctc tgtattttct tgaaatcttt gcatagaatg tatcattact
     5041 taaatcagca tctgagttat tctttaacat tgaacccgta aaatcatcat cataagctag
     5101 atgtaattgc cataacattc caagcctttc aaatacattg cttggtatac ctaagctatt
     5161 tgaagttaca tgctcatata tcttatccat tgttgaacct tcaagtcttg aatgtgtctt
     5221 atcatcaaag gtctgagcaa gtaaagcaag tacattgtta ctagtttcgc tatatgtcat
     5281 ctttccaata tctgtaacat gtcctatctc atgacctatt ccccatccaa ataagtttcc
     5341 tcctgtagct tttccactat catctatttg gaaaggtact ccattcataa gccctggaac
     5401 tgaaccatat tctactccta catgtaatcc agaagcatac ataaatgctc caataaacat
     5461 tctttggtat tttatgttca tacgagattt tggagccata tcatttttag ttaagttaaa
     5521 ttcattatca tctacagttc cattaccatc taaatcttgt gttttaaata ctcctctttc
     5581 tgagtaaact aaatccatta tttgttccca tgcaagcata ctattatata atctatctac
     5641 ttgtgtattt aaatcagaat ttccttttga tatctcttga tatactgctg ttgcaggaac
     5701 atttaatgtt actttatcac tttcaatatc tgtagtgttt aacacaccag ttttttctga
     5761 atatccatat gaattaccaa catttgttcc tggataatat ggttctcctt ttacagcatc
     5821 tttatattta gctaattctt ctatatatgc ttttatcttt ttcttagatt cagaaactcc
     5881 cgcaggactc ttatcattta ttgttccatt tagattaaga tgtggtatct tagtagctcc
     5941 tgctacacgt acttttatat ctcctccact tggagtatct tcagcgtatc ttatgtataa
     6001 acttcctcca cattctatat ctaaactatg aagtttgctt aattgaatta cattttttcc
     6061 agtgttaaga tttatttctc cactcttata tgcaccagat tctccatagt actgtgtata
     6121 tatcaactta ggagtttttc cacttttact tccaacatat actgtgattt catctcctgc
     6181 tctagcagct actcctaatg cctgccagtc attttgcata cctaaattat tggaatttac
     6241 agtatactgt ccgtttttat ctttatattt tcctaattta tttatttctt gatttacagt
     6301 agttacatca gtaagtgtgg ctctatcatt atataagtct tgagctaatt ttaattctct
     6361 ctcaataact gtcttatatg gatgatattc tccactagct ttatctggag tatttaatct
     6421 atcttttaat tcagttattt tttcttgagt tacatcttct tttaattcaa cttgtaggcc
     6481 atccataaat agatttctta catcatcttc tatactgtca tactcataaa acttaagttc
     6541 tgatatatta gacttatatg aataggatga acaaacactt acttgtatct tggtagcagt
     6601 tattggttct tttaatctaa ccattacata cttattatta tttacagggt ctgtctttgt
     6661 ttcaaaagga acatccccca gattgtgtaa ttgaccattt tcatcccaat atcgtacctc
     6721 aaagtcattt attgtcttat cagaaacatc aaaacgaggt gtagccataa aagtatccat
     6781 agtataagat ttatcaaaag ttattattgg tcctctattc gttccctcag ctgcattata
     6841 tgttgggaat gtccaatgtg ttgtaaagtc cccatctact acattgaatt tatcaaatgg
     6901 atttttatca ctatattcac ttttgtcata tccatctgga taaacaacat ctacaatgtg
     6961 atttgttggt attccaaatc caccattttc tttaggagta ttaattaatc tatagttagg
     7021 tgttgttggt gcatccatgc tttcagttgt acctatatat gttttagaca ttccactagt
     7081 tcccaagtgg ttagtagctg tcattctgac ttcatatgtt gtattatcct taagaccttc
     7141 tatctttgaa cttgtcccac gaataagctt atcattgtat tttatccaag acccattaga
     7201 gcctttttct ttatagtaca agtcaaaatc tttagcttgt ttatgatttt tccagcttac
     7261 atcaagagat ttaaatttac ctttaacatt tataccttct ggtggttctg gttttgtgtc
     7321 tggaacaact tgaaattcta atatactatc tgggctaaat tgtataggtt tatagtttga
     7381 atctacattt tctggtactc cgtctaagtt ttctggtgtt gcatctttat aaccactaga
     7441 ccaatctcca tttaaagatt gtatgctaac tctatatagt ccatatgctt ctatatctct
     7501 aacttctatt gtatttttac tagtttgtaa ttttttagta gataatactt ttcccttact
     7561 atcaattttg tctagtataa gttcgtatgc tgatacattt acttcattat tccaataaaa
     7621 agatactttt tcatttccaa cagcagtgct agtcgatatt ttatttattt taggtatgtt
     7681 catctctggc tttggtattt ctttatatac attgtttaaa aattcaactt ttgatatttc
     7741 tgcaagattt ctatcgtttg ctgttgtagc tgttattttt atagttatct tttttactgc
     7801 tacttgttta ccaagattta ttactatatc actattttga acatctgcat atgtttctaa
     7861 tgctgaccta ctatatgtag atgttgtaga gttatcatct ttactgatat taccctcttc
     7921 ttttggagta tcttcatctg aattaggttt atccattgat gaattttctt tatcattatt
     7981 tttatcttga ttggtattag agtttgcttc ttgtttatcg ctattttcct gttgtttatc
     8041 attattttca tctttattat ttgagttatt atcagtctgg tttatatttt catctttatt
     8101 atttacttct tcttgattta cttcttcttg ttcgttattt acttcctctt gttgctcctc
     8161 atcttttaag tttttcatat attctttgtt ttcataagga atctgttgaa cattaccatc
     8221 tttgtcagta acctcaacta ttccttttgc tggagcagta ccttctggag cttttatatt
     8281 gatgacttcc atattaagtg cttctgataa agctatatcc attactgctg gtttttcctc
     8341 agatatttca tcattttttg aagatattgt aactccatta ttttctccac taaataaatt
     8401 ttctacatta ccattaatat ctacatcact atttcctttt aattcaacct tacttgtatc
     8461 tactatagga ttggtagata ctatactttc taggcttttt gcatcttcac tttgtcctaa
     8521 atttttctgt acataatcta agtcaacaat atctaccttt ccatctctat ttaaatcaaa
     8581 ttctctttta tttgaatcta tattctctaa aaccttatta taatcactct tatctacttt
     8641 accgtctcca tttacatcac ccattaagaa caattcataa tttaaaggtt tatttttatt
     8701 atctacactt gctctattgc ttaataagac tctttgtgaa taacttgata tatcaatgtc
     8761 tttaatttct ttgttcttaa atccatctcc agagacttct acattgtatt ttccaacagg
     8821 taaattatta aatacaatat tataatatga tatattctca tctttatttt ttatttcact
     8881 tctacttgca gataattttt ttatagtata ttctatatta tctgtcccaa catttactgt
     8941 tcctgaatct ttttctccaa gctttattat tccactattg ttactatcat cttttaatcg
     9001 taactgcata ttagtcatac tttctgactc gctatttttt attggcagtg aaaaatttaa
     9061 atctacttca agactccccc ttaacttttc tgtaactgat ttttcaactg cccttagctt
     9121 cccctctaat ataggttctg caaaaacgtt tagtggtgca ctacacatag atactgctag
     9181 tacacaagat attgcctttt tcatgaaata acaatcctcc cttaataaat atctaatttt
     9241 tcatgaattt aaatactata agtttcagac aataaaaaaa gacactcaaa gagaatctta
     9301 attataaaat aaaaagactt tactcttttt agcaactggc tgatatggct ttaaaagctt
     9361 taatccctat agttttgcgt cattagattt ccctaatttt gccatttaat tttcactact
     9421 ttcttaccca ttttatacta tatttaaact ttttaatata atttttttag attaaattat
     9481 aaaaaaataa catttatatt aatttattaa tataaatgct attttccatt ataatttaat
     9541 tatttatata gcttccttac aagcataatt ttgtgtatat tttcttattc tttatatctt
     9601 ccataaaatt catgtgtagc atatagattc ttatctcctg ttatagctat accaaatccc
     9661 attatttcat accctttatg caacatatta gttccttctt ctggatttgt cttccactca
     9721 ttaaaaataa agtttcctat atcatctgca tctctatttg tatatacagg tttatctgga
     9781 attttatatt taattatatt ttcaccttga actgctatat atccaggttt aatctcactc
     9841 caatctaagt atttcaaaaa agtagaatat gaattttttc catttatcgt atgagataaa
     9901 gtcttcttat ttgccattaa attagaccaa tcatttgcta gaccctctaa tctgcttgct
     9961 acagataacg ctcttactcc attctctttt ctatactgct ttgtaagagc atatacttta
    10021 ccctttattc tctctttaaa tgctctatca tttggattgt aatataaacc ttgttgattt
    10081 ggtgaagctt gatttataca ttgcttgata acattctgat ttatgcctcc tagtacagtc
    10141 aatttgtctg caccacttaa aatactcttg ttactgccat tttcaactaa aactacagga
    10201 gcattttttg ctattgtaga ggcagccaaa gcgtctgtta attgtaagcc tttacttaga
    10261 taaaattctt tactattttt ataaaactct tgtataacta tcttattagt ttcaaatcta
    10321 tctgtgccac ccaatctaat agaatttgtg ctcttaacta attcgtcgct tattatttca
    10381 ctagaaccaa gcgcataact ctttaagcct gtcgtgtcaa atcccacact atttccatct
    10441 gtaagtatta taggtactcc atctctagca gctactggtg atgcacttat cgcatctgct
    10501 tctcctgtaa atccattggc tataattact ttatctattg gcttaatttc tttgattttt
    10561 tcagctattt ttatacttgt atcaaatcta ttttcaccaa atattctttg tacaaccttc
    10621 tttttggata gtaactgatt ctcaacattt ttacttattg ttgattctga acctattata
    10681 tacacagtct ttgctttgtt taatctttcc atagttgtgt ttggaatctg gttttgtttt
    10741 gtcatcaaaa taggcgcatt taaggctcca gctaaaccac ttgcacttag accatctgct
    10801 aagctattat ctgagttgat tagtattgct gtattgtagt tttgcttatc tgctattttt
    10861 gctgctgtct catatctgtc attccctttt atttgctcaa ctgatgtcaa cgcatttacc
    10921 ataggagtat ttaccattac taaaaatagt gtaagtccta tagctaatat ctttttacta
    10981 ttcttcatat tattttctac ccccaatgta cttttcatat tttttattag tactcatact
    11041 tatttttaat caaaagttac aattttgtta ccatatttta tatatgatac catagttatc
    11101 catacaactc aaacaatata cctaaagttt ttattctcta taaattcaaa acattataat
    11161 ttattttatt taattacgtt ataagttcaa aataatttat gttagtaata tgtttaatca
    11221 ttataagaag tatcttttta taataatttt tgcaatatga atttctcaac attataatca
    11281 aaaaataaaa taaggtatct caatctaatt ctaaatgaga caccttattt ttattatttt
    11341 atcttgttat ttgtatattt tataatatct acactatgtc ttacatatta acgcattgta
    11401 taatcatata ttatctaaat aaacttttaa tattaattcc tatatcttat tagttcttag
    11461 taaataagtt tattttttct gctatttttt caatagcgtt tttagctatt ccttcaccta
    11521 tttgtactaa cttagtagca ttcttaagtc ttaactcaac tacttcttct tgtgatttag
    11581 aaagttcttc tgtagttaat actattggag cctttgaact agctgcaagt ggtgctgctg
    11641 taagtgcatc aactaattgt ccatttccac ctacataacc atcttttgct acatatgctt
    11701 tagttgcacc tgcatagtat ttattgatta ctttagcatt agtatctttt ctattttctc
    11761 cagctaatct ttcaacttta ttatttaaat ctatatcaac taatttgtct tcaacttctt
    11821 ttgatacaga attttctcca cccactattt ctaattcttt tccttttaat aatttttcag
    11881 catttgcatc taattcgtta cctgtaacta ttattggagc accaaattga gcagctctag
    11941 ctgatatact catagcatca gcttctccat ttccacctac tacaaaagca gtcttaaatg
    12001 tatcttttaa ttgttttgct atttctaaag aagtttcaaa tctatcttct ccagaaactc
    12061 tctcaacttt acttacacct aatttagaaa gtttttcttc agtttctttt gatactttag
    12121 attctccacc tactatatat attttcttag aagatagatt acttccaagt actcttaata
    12181 tttcagcttc tatttctgat ggtagtgaat cttttttaga taataatatt ggtgcatttt
    12241 tttgagaggc aagtggtgct gatgctaatc catcaactat agcatcttct ccaactaaaa
    12301 ttatagcttc tgcttctcca tctttaaatc tctctttact aacttctact gctgttgtaa
    12361 atcttgaatc accagataaa acttctactt ttaattcttt tccatctttt acatcagtta
    12421 atactttgtg taagtctcta actaacttat ggtttttact tgaaacactt attgtttctg
    12481 gcttttcatt tgccttgctt aaaactatat caaagcttga tttttctggt ttatctttat
    12541 catcactatc ttcttgttct tgagtaagga ttgcttcatt ttcaaatgtt aaagcatatc
    12601 catttttaac tttattaact atttctcttc ctaatgtagt taatctaatt ccatcaaata
    12661 attcttctgc tgatatgtct tgtaaatctg cgtttttaac tgttatcgta tgtaattctt
    12721 ttgaatctat gtcactataa ctcttttcat aaccttcaaa agtaccttct tctgatgtta
    12781 tcacttttga gaaatctaaa tgttggtctc ctacatttaa tgtaataaca tttgctgaat
    12841 cttttgctct ttttacttca actgtatttg tagattttat agttgctgtt aacttgttat
    12901 cagaatcttc tgctaaagtt gcattgtaag cattaactgc atctactatt tcttgagcag
    12961 ttttgtagtt ttcaatttta tagtcaacta cttttccacc taacacttga tgccctttat
    13021 cttgaatagt aacttttaaa ctttgccctt ctgttaaaga gtttatttta ttttgtaatt
    13081 gagttgcatt agttaagttt acattgtcta cttttatatc gtaaactcta tcatttacat
    13141 ttgctcctgc ttttgtatct tcaaacttaa cttctaatgc ttttctaacc tcttcgatta
    13201 gtttagcaga atctttcgca cttactgtgt aatttttatc aacattttct gtcacggtat
    13261 tgtctgcgaa tattggtgct gctgcactca taactgtagc acctgccatt actattgcca
    13321 tacttctctt tttgttgctt aacatattta tgtcctccga atattatttt ttatttttta
    13381 tattcgtatt tcccacacat aaataatatt atatataata ttatttttca atatatttta
    13441 tgtgtttaca taatttacta acacaaacac taataatatc ttcttgaaac ccttccccct
    13501 acttaggctc tctataatta tgctcaaaga tagaaatcct attttatagt gattttctac
    13561 taaacaatca tatactaaca aaagtattca aactccattt ttatatacta ctatgcacta
    13621 atttttgctt tactcttatt acttaaatat atatcactaa attaatatct atctccatat
    13681 attaaaatat ataacatatt ataaaaatca tcataaatta gagtttaaaa ttaaaaatta
    13741 ttctaataca tgtaattgat aaaaaataaa atataagagt agctacttta aaataaatgc
    13801 tcttacatga ttagatattt ttgcataatt aaacgataag aaatcaaatt tacttctaca
    13861 taaatagaat atatattttt atataataat tgaaaataaa agaggatacc tcataatgat
    13921 aaaagaatca ctttgagata ccctcttaca aacaactaaa tcaataattt tctatctttc
    13981 acactcttga tttgcaactg tacaagaagt tttacaagct gattgacaag aagtttgaca
    14041 ctctccacat ccaccttttg cagcactttg ctttaaagta gcttgagata aagtttttac
    14101 atgtttattt tccattttca acgcctccat ttctaattgt ttcctattga ttatatcata
    14161 aaactacttt aatataaact ctatttaaag ttgacaccca atacgcctcc aatgcctcct
    14221 gctgctgata ttagcaataa cttataaatc atccctattt caaatacaaa cttttcttgt
    14281 gctaaaaaca cagtcaaaaa aatacatact atgtacaaaa gtcctactaa aagcccatac
    14341 ataagtcctt tttctttcat gtgttttgaa gtgtaaaacc ctcctatagc tgcagaaata
    14401 gtagttataa atgatgagac catagttata ttatctccac caatatctgt aaatgtcaaa
    14461 aataagttat acactaataa aacagccaaa gttattatat atgcatatcc tagaccttta
    14521 aaaatataat tagattttcc cataaaaaaa cctcctctca aattaatata tattcgagaa
    14581 aaggctttta aattactaat ttagtcttct tctatttctt cttttttaga tttaacagtt
    14641 cctatagccc atttttcaaa tggaacttta gttctatttg gtcctaattc taatattaca
    14701 acatcatctt caactttagc tacattagct actattccac ctattgtaat gaccttgtct
    14761 cctacactta ggctgcttct catttctttt aattgtttgt cttttttctt ttgaggtcta
    14821 atcattagga aataaaagat tgcgattact actacccata gacctatact cataattatt
    14881 tgttgctgtg gcattaattt ttcactcctt tgtaaattat actcttttgt aaatcataat
    14941 aaatgtttat ataacaattt actttctcta tctttgagta ctattgaata ttatatatta
    15001 aaatgattat aattaatagt gcaaaaccta tatttcatat ccatattttg caaaaaattc
    15061 atttctaaaa tcaagtaatc tatcttccat tatcgcttgt cttatttgtt tcattaaatt
    15121 taataaaaag tgaagattat gagtagttat taatcttgca cccagtattt catttgcttt
    15181 tataaggtgt cttatataag ctcttgaata gtttttacaa gcataacaat cacattcagg
    15241 gtcaagtgga gtaaagtctt cagcataagt tgcatttcta actactactt taccttggct
    15301 agtcattgca gttccatttc tagcgatacg agtaggtaga acacaatcaa acatgtctac
    15361 tcctcttata acaccttcta ctaagtcatc tggactacca actcccatta ggtatcttgg
    15421 tttatccttt ggcataagtg gagttgtatg ctctaacacg tcatacataa gtggttttgg
    15481 ttctccaaca ctaagtccac caatagcata tcctggtaaa tcaatattag ttatttcttt
    15541 cgctgattgt tcccttaagt ctttatacat cccaccttgt attataccaa ataaagcttg
    15601 cttgtcggta ttattatggg catctttaca tctttttaac catcttgttg ttctttctaa
    15661 agaatttttt acatattctc tatctgatgg gtatggtgca cactcatcaa atgccatcat
    15721 tatgtctgaa cccaatgcat tttgtatttc catagctttt tctggagtta gaaaatgttt
    15781 tgaaccatct aagtgtgacc taaattctac accttcttct tttatctttc ttaaaggccc
    15841 tagactaaat acctggaacc ctccactatc tgtaagtatt ggtttatccc aattcataaa
    15901 cttatgaaga ccaccagctc tttttataag ttcatgacct ggtctcatat ataaatggta
    15961 tgtgttacta agtattattt gtgaaccaat ctcttttaat tcttctggtg tcatagattt
    16021 tacagttgct tgagttccaa ctggcatgaa tattggtgtt tcaataatcc catgtggagt
    16081 gtgtaatctt cctaaccttg caccactctg cttacaagtc tttatcaatt cgtatcttac
    16141 tgcgtacata aagttctcct taatcatatt tatttctcat tatttcttaa gatatatttg
    16201 taataagcta ttcatataat ttattgtcta aatagattta tcttcgtctt ctttgttctg
    16261 ttgttcctta attgcttctt catcatgaat actcattata ttaagagcac tcttgtcttt
    16321 tgttactaaa aactttttta tagcaaatag tcctgctata gctataactc ctattaaaac
    16381 atctatcata ccttcatttt taggcagtag caacattttt ctagcaattg cgtaaagtaa
    16441 tgcctcaata aatgctcctg gtatatgaag agatagcatt actacaagtt caacacctat
    16501 tactaaaagt aatatttgtg ctaaaaaatc attaagctga ctgtattgta ctggattttg
    16561 aaaatcaact atatatgctc cccacataag tcttagaaca tctatagttc ctaaaaatac
    16621 tgctattaga actactactg ctaaaacacg ttcaaatata aaagcaatct ttaatatagg
    16681 gttattcttt ttttgttttt gtaaactatg catccattac ctccctactt tataatcata
    16741 gcatctccaa aactgaagaa tctatatctt tcttttactg cctcattata tgcatttaaa
    16801 acattatcct ttccacaaat agcacttact aacattatta gtgtagactc tggtaagtga
    16861 aaattagtaa taagtttatc taaaacttta aatttataac ctggatatat aaatatttct
    16921 gtccatccac tagtttcttt catctttcca tactcattac aagctgattc tatagttcta
    16981 caactggtag taccaacaca tattacattt tttccatttt cctttgctct atttattttg
    17041 tcagctgctt cttggctaac catataatat tctgaatgca tcttgtgatt taaaacatcc
    17101 tctactttta ctggtctaaa agttcctaag ccaacatgta gagttacaaa ggctatatct
    17161 acaccttttt cttttatttt atttaacaat tcttctgtaa aatgtaatcc tgctgtaggt
    17221 gctgctgctg aaccattatg ctttgaataa acagtctggt atctttcttt ttcatctagt
    17281 ctagcagtga tatatggagg tagtggcata tttccaagtt catccaatat ttcttcaaaa
    17341 attccatcat aatggaattt tataattctt gaaccttcat ctgataaatc tacaacttct
    17401 ccaattagct ttccatttcc aaaagaaaat ttagtcccta cttttgctct ttttcctggt
    17461 tttactaaag cctgccaagt atcttcctct gttcttttta ataataaaaa ctctatttta
    17521 cctccagttt caagcttctc tcctattaat ctagctggta taactctagt attatttaat
    17581 actaagcaat ctcctggatt taaatattct attatatctc taaatacttt atgttcaata
    17641 ttacctgtct ctttatctaa taccatcaat cttgagctag ctctatcttc tataggaact
    17701 tgagctataa gttcctgtgg taagtcaaat ttaaaatcac ttgttttcaa tgttaaactt
    17761 cctctcttaa aatttctcca gctacaataa tatcaaaaaa acaacttatt ttccacaata
    17821 ttaccataat ctatcaagaa attgctattt ttaacagaca ccatatccac aatatataga
    17881 tatttttcca cgatatacat gtcttatcca caatatatag atacaataca cacaattttt
    17941 atcgtgttta tccacagtat ctacagatat aattaccatt ttgtggatat gtttgaattt
    18001 ttagccattt tagaaatatt ttaatttaat gactctttta ttttataaat actcgtataa
    18061 tctattttta tttttcatta ggatatggaa tttttaagtg ttcatatgct aatggcatag
    18121 ctactcttcc tctaggacct ctatttataa atcctaattg aagcaaatat ggctcatata
    18181 catcttctat tgtatttcta tcttctccga tagaagctgc caatgtatct aaacccactg
    18241 gtcctcctct aaatttttct attatagtca taagaagctt ctcatctaca aaatcgagac
    18301 ccaaactatc gactcctaaa agttccagag catcttttgc caccttatca gttatttttc
    18361 catcagctct gacttgtgca aaatctctaa ctctttttag taatctattt gctatccttg
    18421 gagtccctct tgaacgtttt gcaagttcta atgctccatt agactgtatc tctgcatcta
    18481 agatgcttga agacctaagt actatttttg aaagttcatc aactgtataa tagtccaatt
    18541 tacaaataac accaaatcta tctctaagtg gatttgtaag cataccagct cttgtagtag
    18601 ctccaataag tgtaaattta ggaaggtcaa gtcttatgct tctagcagat ggccctttcc
    18661 ctattattat atctaggcaa aaatcctcca ttgctggata taaaacttct tcaacacttc
    18721 tattgattct atgaatctca tctataaata aaacatcatt ttcatttaaa ttcgtaagta
    18781 tggctgccaa atctccagct ctttctattg caggtcctga cgtaattctt aaatttaccc
    18841 ccatctcatt tgctattata cttgctagtg tagtttttcc aagacctggt ggtccatata
    18901 aaagcacatg gtctaactgc tcatttctag atttagctgc ttctataaat atactaagtt
    18961 gttctttgga tttttcttga cccaaataat cttctaaagt ttttggtctt aaactatttt
    19021 ctatatctat atcttccatc ttcattgtag aagttattat cctattttca tcttcaaaac
    19081 cttgcattta tacccctcct ctcatacttt tgaaaatcta ctttatatat tttcaaattt
    19141 acataaactc cttaaatatt gttttaaaat ccaaatatta taaaatccaa atactatttc
    19201 aaggatttac tcattatata tgtaagtgct ttctttataa tagcttctgt attcatacca
    19261 tcttttttac atttttgaac tgcctctttt gattccgaca aagtatagcc taaagctaca
    19321 agtgcatcta cagactcatc ttgtgatatc aaggtaggtt tttgtgataa taatgttggt
    19381 tcaaactcta tgttattttt gtctacctta tccttaagct ctaagacgat tctttctgct
    19441 gtctttttac caacaccagg agctttggat aattttccaa tgtcttcact taaaatatat
    19501 gctcctaact gtgctggtga tgcaaatgat agtattgaaa gcgccacttt aggtcctatt
    19561 ttagatacag atgttagtaa ttcaaacatc ttaagttctt ccctacttac aaaaccacaa
    19621 agactcatat catcttctct tacaattaat ttagtatata tttttgtggc ttctcccact
    19681 tgtaaattca ttattgtatt ggatgataca tttattttat atcctatccc attattttca
    19741 acaactatac tgtctatata aatttcttct actgtacctt ttatataact atacatactt
    19801 accacctata ttctttagag ttttttcaag tttgtttgaa tgagcatggc aaatagccac
    19861 agctaaagca tctgcaacat catctggttt tggaactttt tttagactta aaaatgaagt
    19921 taccatctgt tgaacttgtg ccttatctgc tctcccatat ccaactacac cttgttttac
    19981 ttgaagtgga gtgtattcat atacaggctt cccattatga gcacatgcaa gcatagtaac
    20041 acctctagct tgtgcaactg ttatagctgt ttttacattc ttgttaaaga ataattcttc
    20101 cattccaact tcatctatat tgtaattctt tactattgta tcaattcctt tatacacaag
    20161 ttccaatctt ctcgatatat tcatatgggc aggtgttgta actgctccat aatcgattac
    20221 tttaaacttg ctatttttgt attcaattat accatatcca actatggcta tacctgggtc
    20281 aatccccaat attatcattt tttaaaattc cccctaaaaa taaaagaaat accaaaatgt
    20341 atttctcata aaaacttatg ttctaaatca ttatatcata aataatatta acaaatcata
    20401 aaatgctcta tgtaaaatat aaaatcaaat aaaaaagtta tatcaaagca agattttacc
    20461 tcaatataac ttttatattt attacaaata aattattgta tttttatagg aattaaatgt
    20521 gactacaatt ttaatactaa tctatttaat actaatctat ttaatattaa attatttatt
    20581 attaatttac ttagtattta acttacttag tatttaactt aaaataatat taatttacta
    20641 ttaacttgca aagtcttcta atcttgaata ggcctcttct tcagtatcca taactacacc
    20701 ttttttgatt tcatcttgaa ctgttttagg aagtgaatct actcttattt ttgttttttc
    20761 tactaatgtt ttgcttccac tatcatcata tttatatagt gctatatttc cattatcatt
    20821 ttcaatagta tatttacctt ttatagtaac atccattgct tgtacatctt tattatcact
    20881 atatttagat tctaccaata tgatttcatt tttatccata ctctttattt ttttagttgg
    20941 atattctttt ttaaaatatg atactatttc tgacttcgtc ttatctaata atgactctgg
    21001 aactattcct gccattgtaa gtgttctctt atagttagtt tcattttcgc cttcactttg
    21061 aagccaaact tcacaatttt tatttaatcc aaaagcttct tttgactttt cattcatatt
    21121 cgcactagta cttacaactt caccagtttg aactccattg tgttttaatc ttgtccctat
    21181 ataaactccg ctacttaata caaatactcc aaccagtatt aaggcagata ttttccaagg
    21241 aaataattct tttttcttct tttcaaacat tgattacgcc tcctttttct attattttct
    21301 ccaagctgta agtttttata caatttaggt aaattttaga agaaaatata tttatatttc
    21361 aaattactct aagaatagat attttctaaa aggtagtttt ctcttaatgg ttatattctt
    21421 gtaattatat ggacataatt tataataaat aatcgtttag gaggtaataa ctttggaaag
    21481 aataaactgt aatgtaatta actgttcaca taacaacagc catatatgtt atgc
//
LOCUS       DAJMZY010000073        21438 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.073, whole genome shotgun sequence.
ACCESSION   DAJMZY010000073 DAJMZY010000000
VERSION     DAJMZY010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 21438)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21438)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21438
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.073"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            complement(144..1022)
                     /locus_tag="OE968_002542"
     CDS             complement(144..1022)
                     /locus_tag="OE968_002542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HCP7219817.1"
                     /translation="MRYDIAIIGSGPAGLSAAINAKIRNKTIIMFGNDNLSNKLVKAP
                     SIDNYLGFYDISGDELKDKFKSHIDSMDISIENKRINNIYAMGEYFTIMSGNDMYEAT
                     TVILATGVEYTRPIKGEEEFLGRGVGYCATCDAPLYRNKKVAVIGYNEESKEEANFLS
                     ELTSKTYFIPMYKKDNLMRSSDNLDDSIEVIHDRPVQIDGDKLVNKVSFKENHIEVDG
                     VFVIKDSTAPSALVPGIEIDGIHIKVDNNMKTSIDGCFAAGDCVGKPYSYIKAAGQGQ
                     IAALNAVYYLDKLKRA"
     gene            complement(1039..1356)
                     /gene="trxA"
                     /locus_tag="OE968_002543"
     CDS             complement(1039..1356)
                     /gene="trxA"
                     /locus_tag="OE968_002543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HCP7219818.1"
                     /translation="MAKVINTSEFRSSVEGSKGVVVVDFFATWCGPCNMLGPVFAELG
                     EEMKDKARFVKVDIDESLEIAQQFNVSTVPTMIIFKDGKPVETLIGFMPKNKIEMQVK
                     SYL"
     gene            complement(1506..2738)
                     /locus_tag="OE968_002544"
     CDS             complement(1506..2738)
                     /locus_tag="OE968_002544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HCP7219819.1"
                     /translation="MINKNVFTSTKNHLIKMYIIVVGSFLIIFSIFIYSYFRGLTYSG
                     IDSEINDELEYIVSQFKRTSFLNPIRLKDPKDMVYVYEDGRISYYTQNEYFDELLPDR
                     RLDKKNSFFKYTENGYTFRELNVDVGRYQIQIIRNIDSEMNSLRQLTSVLIIGILISV
                     IITYFVAVYLTRKALIPIETAWKNQAKFIQDASHELRTPITIVSSKLESMLKSPESTV
                     NDEVETIATAMKETRRLKKMITDLLSLTKEDSIVKVNLEEIDLEKLLEEISEDYIDIA
                     EFQEKRFVFNSKLKNKVIITDKNKLRQLILIFIDNAFKYTKLGDEIALELKEDIEDEV
                     TLLISDTGIGIKKEEIPLIFDRFFRSENVRNKDLEGSGIGLSIARMISLNLSIDINVT
                     SDVDIGTTFELSIPKKLK"
     gene            complement(2728..3399)
                     /locus_tag="OE968_002545"
     CDS             complement(2728..3399)
                     /locus_tag="OE968_002545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCP7219820.1"
                     /translation="MKVLIVEDNKILLESVVEELSKHFETEKCEDGEEALYLVNQNIY
                     DLVILDLMLPNINGFDILKKMRVNNIDTPVLILTAKETLDDKVEAFTIGANDYLTKPF
                     YMEELVARVYAILRTNGKIKERNGLEFKSLYLDTLEKRVYIEKEEIKLQNKQFNLLEY
                     FVLNKGSILLKEQIYDRIWGIDSDATIEIVEVYVSNLRKKLSKYGYDKYIKTKRKVGY
                     IFDDK"
     gene            complement(3415..4251)
                     /locus_tag="OE968_002546"
     CDS             complement(3415..4251)
                     /locus_tag="OE968_002546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219821.1"
                     /translation="MNKIVKKSISLMIILTIFIFMLTACEKDEQPDSVDIQTEDKNEI
                     KIDEGNAKVLNIGKSEIINIDEGDKVDTSTKVENNSTFNISNVELIYNEYDENKKIIS
                     SDSKALLDMTLMPGKVAYIECGHKTFVKGVEVYAYEYEAEGKIVYVNLKENTINIRNN
                     NIKLENSSQYEVLSTSELKKVNESNEGITYQVKVKNSSSKDLGNIILKTAEVNENGEY
                     LTVNRVPSYKILKPSEETDIDILCSTKAKSVEIVGYTYDDIKEKANVDIDLKSHKVKI
                     DK"
     gene            complement(4277..4951)
                     /locus_tag="OE968_002547"
     CDS             complement(4277..4951)
                     /locus_tag="OE968_002547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HCP7219822.1"
                     /translation="MNNNEDRIDKFLELQSKGFKFAEIAQNLKISQSTLRTFLNKKGY
                     KSEKGKYIFKDELNYNKSLDNRNLEEEKAKEYEKSKKNTISNRKKVSTKKKISNEKAL
                     SKSVEQIEFNDTGLKNAKPKQNIKPKKDRKINITQEDLDKLCEVYDWYLEVKDYNIKP
                     KKVSNKKDVHIDDEHIDELKTTRIRIDKEIWNDFERLCSNSNFEKHQILTQALKEFMK
                     KYKNLL"
     gene            complement(4965..5693)
                     /locus_tag="OE968_002548"
     CDS             complement(4965..5693)
                     /locus_tag="OE968_002548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HCP7219823.1"
                     /translation="MMFDRVKWNKLDYNELLEYMMSIQDIKYRDFNKKLIPGTENIIG
                     IRVPNLRKLSKEISQGNWKEFLEVAEDTYYEEVRLQGMVIGNINSNFEETLYYVKRFI
                     PKIDNWSVCDGFCSDLKSMKKYKENMYDILKKYVYSKNPWEIRFALVMFLIYYVDDKH
                     IKEIFEYCNNIQSEEYYVKMGMAWLLSICFIKCEEETFLYIKNNNLDDFTYNKMLQKI
                     IESNRVDLEKKNIIRSMKRKTRRC"
     gene            complement(5820..6509)
                     /locus_tag="OE968_002549"
     CDS             complement(5820..6509)
                     /locus_tag="OE968_002549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HCP7219824.1"
                     /translation="MDRYSEITNKNQREIVLLKGFPCIWGKCSFCDYIDDNSNLEEEM
                     NKLNLKVLKNVTGKYGVLEVINSGSCFELPKDTLEKIKCIIKEKNIKKLFLESHWSYK
                     NRLKEMREYFEIPVVFKIGVETFDNDFRNNILNKNANFKTPQDVKEYFDSPCIMVGIK
                     GQTKEMIDKDIEIILNTFEKATVNVFINNSSSIKRDEELVKWFVSKYKFLDENPNIEV
                     LYNNTDFGVGD"
     gene            complement(6517..7080)
                     /locus_tag="OE968_002550"
     CDS             complement(6517..7080)
                     /locus_tag="OE968_002550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HCP7219825.1"
                     /translation="MKRKICVKTITLIAFGISINIIGAFIAMGLRLPVYLDSIGTIMI
                     ASLLGPKYAVVTGVFGSLISGITFDVYSLYFAPVQISTGLLAGIAFKKNFLRGLKTPL
                     GVLLFAIPTSIISSIISAFLFGGMTSSGSSYIVQILKVLGLGDVFSVFVTQVFTDYGD
                     KLLAVVLVNLGLNAVPKTLKVSLTGGK"
     gene            complement(7082..8050)
                     /locus_tag="OE968_002551"
     CDS             complement(7082..8050)
                     /locus_tag="OE968_002551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside hydrolase"
                     /protein_id="HCP7219826.1"
                     /translation="MEKRKVIIDCDPGIDDSLAILLALNSPELEVIGITTCCGNVPAN
                     IGAENALKTLQMCSSLNIPVYIGEEAPLKRKLVTAQDTHGEDGIGENFYQKVVGAKAK
                     NGAVDFIINTLYNHEKVSIIALAPLTNIAKALIKDKKAFENLDEFVSMGGAFRIHGNC
                     SPVAEFNYWVDPHGADYVYKNLSKKIHMVGLDVTRKIVLTPNIIEFINRLDKKMAKYI
                     TEITRFYIDFHWEQEGIIGCVINDPLAVAYFIDRSICKGFESYVEVVEDGIAMGQSIV
                     DSFNFYKKNPNAIVLNEVDEKKFMYMFLKRLFKGYEDIIDSVEGVI"
     regulatory      complement(8151..8194)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            8559..9188
                     /locus_tag="OE968_002552"
     CDS             8559..9188
                     /locus_tag="OE968_002552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCP7219827.1"
                     /translation="MSIKERRKNEKEEMKKKIMDASIEIINQHGYENLSIRKIATKIE
                     YSPTTIYLYYKDKAEIISDMTNKLYNTVESNAIDIMNNCSSLPIDKQIIEIMTSFIKT
                     LSSEPEMAKSIMYSRMNIIFASENTNNTPSNNGIKMLDKFLSIGIEQGIFKKNIDKSS
                     WMLISALLGFVLCVVENKLYSLHNFSQLIENFLDILVGGLYNENSQQGY"
     gene            9163..9567
                     /locus_tag="OE968_002553"
     CDS             9163..9567
                     /locus_tag="OE968_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-binding protein"
                     /protein_id="HCP7219828.1"
                     /translation="MKIRNKATNKKKKYVKISIALFFVFICIIIVIVSNLKPENLVVK
                     DIDINNVKNGIYTGSADNNLVKATVSVEVNNGKIQNINILKHDHLLGKPAEKITTSII
                     KQQSLDVDAITSATYSSNTIRKAVENALRKGE"
     gene            9570..10043
                     /locus_tag="OE968_002554"
     CDS             9570..10043
                     /locus_tag="OE968_002554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HCP7219829.1"
                     /translation="MNTIIIYSSKYGCTKDCANILKNKLSDNVTIVDINNNNKIELSK
                     FDKIIIGSSIYVGSVSKKIQVLCNDNVELLNKKQVGIFLCCGFSEQADKYLKSNFPSS
                     LLESANAIGIFGSEARLEKMKFLDKLIMKAVSKGNYDSFRISQDNIDNFLINLNS"
     gene            10613..11278
                     /locus_tag="OE968_002555"
     CDS             10613..11278
                     /locus_tag="OE968_002555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HCP7219830.1"
                     /translation="MIKLIGILIVVIGFILKIDTLFTVLLAGVATGIVAGLDFNQIFT
                     ILGDSFVSNRGVSLFILTLPVIGVLERYGLKQRAVSLIEKLKRLTTGKVLTIYMIARQ
                     IAGALSIRMSGHPQFVRPLVNPMAQAAGLSNSDELKESDEEAIKALSAASENYGNFYG
                     QNLFAGSSGVLLIASTLTQFGYNVTGLNIVKASTIMAVIALVVATIQFTLYDKKLNKS
                     HKK"
     gene            11300..12232
                     /locus_tag="OE968_002556"
     CDS             11300..12232
                     /locus_tag="OE968_002556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HCP7219831.1"
                     /translation="MQNFINISLEIFYALMGFLMIVIAYKSFTTINNNKKYGTSLFWI
                     LISLPFIFGRLIPANIIGIILILSSLLTLSKQVVFAKYEEPDENFGKEQADKLKNKIF
                     IPSLILAFAAVVVAMSLSNFDNSSQFAIGVGSIIALISALIITKAKPATSVQDGSRLL
                     QQMGPASMLPQLLVALGALFTQAGVGEVISTMISGVVPADSRLFGVIAYVLGMVIFTM
                     IMGNAFAAFSVITAGIGIPFVLSQGGNPAIIGALALTAGYCGTLLTPMAANFNIVPAA
                     LLECKNDYIVIKYQAPVALVLIIAHILVMYFLGF"
     gene            12253..12894
                     /gene="pcp"
                     /locus_tag="OE968_002557"
     CDS             12253..12894
                     /gene="pcp"
                     /locus_tag="OE968_002557"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HCP7219832.1"
                     /translation="MKILLTGFDPFGGEPINPAQEAVERVNNNINGAEIIKITIPTVM
                     TKSVEAIDKAIQEHNPDIVISVGQAGGRFDITPERVAINIDDFRIKDNEGNQVIDTII
                     KEDGEPAYFSKLPVKAMVKHMNENKIPASVSNTAGTFVCNHVMYGILYMIDKKYPNIR
                     GGFIHIPYTTSQVIDKKNTPFMSLEEIVKGLELAIEACIIYKEDVKEIGGEIS"
     gene            complement(13014..13346)
                     /locus_tag="OE968_002558"
     CDS             complement(13014..13346)
                     /locus_tag="OE968_002558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCP7219833.1"
                     /translation="MSIDCISNTDLSETGFSYTLSLISGKYKMIILYCLVEFEVVRYN
                     ALKRYINTISYKTLSLSLKELEADNLIIRTEYPQIPPKVEYSLSERGKSLIPILDAMC
                     EWGERNRP"
     gene            13612..14232
                     /locus_tag="OE968_002559"
     CDS             13612..14232
                     /locus_tag="OE968_002559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HCP7219834.1"
                     /translation="MKVLLINGSPNQYGCTYTALNEITKVLSKHDIKTEILYLGKETI
                     PGCISCASCFETGKCIRNDKVNKLIEDLDNIDGIIIGSPVYFSSATGQLTSFLDRLFF
                     IAGSRMATKLGASVVSCRRGGASATFDQLNKYFSISNMPIVSSQYWNQVHGFTPEDVM
                     KDEEGLQTMRTLGENMAWLLKCISAGKKAGIKEPQYEETIMTNFIK"
     gene            complement(14557..15381)
                     /locus_tag="OE968_002560"
     CDS             complement(14557..15381)
                     /locus_tag="OE968_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraX"
                     /protein_id="HCP7219835.1"
                     /translation="MDFFKKGISGFTIKILALIFMTFDHIAAFMPQTMQIPIWFHWVG
                     RISAPLFIFMAVEGFYHTSNRKKYISRLYIWSVIMAIGNQIINNVFSHPEGAIIINNI
                     FSTLFLIAIYLQAIEFIKKFRKEKEIKYFIIGLLMIIIPIILGIFTVALLFKVTNRVI
                     ALFMILVPVPFLVEGGPIWIILGIIFYLCRGKKFSLSICYVLMCIFIFTTMSNGDYSL
                     KNSILQNYQWMMIASLPLMLLYNGEKGKSMKYLFYLYYPIHVYILYILGIYLINGF"
     gene            complement(15392..16795)
                     /locus_tag="OE968_002561"
     CDS             complement(15392..16795)
                     /locus_tag="OE968_002561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HCP7219836.1"
                     /translation="MKWKITRNFIFTIVFVAISVVIINIISILYVISTNSFFKVVDSG
                     NNPEEFARSFEKDLYEKDGEFKLSKIGAEKLEKSNSWIQVLNDLGEEVYGVNVPKDTP
                     KKYTPFQMVNNYKYIETKYVNFVLEKYLNKKHLNIIVGIPSRDISRIILTYSQNNIKK
                     TLNKVIIITLVIDSVVALGVGYLFSRKLTKPISSVLWSIETMANGNYSLYLKDRGIYE
                     EVFKNINMLADTLRVNEVERKENEELREEWLANITHDIKTPLASIQGYAEIINDKDYE
                     FEEDEIQEYTEIIYNKSKYIKDLVDDLNLSTRLKNNTIVLDKKKINLVSLVRDIIIDI
                     LNDNRYKNRNIEFESNEDLIEVYVDSILFRRAITNLIFNSIVHNSEGTLISVEIVKKD
                     NIEIIIKDNGIGISKSDLKHIFKKYYRGTNTGEMHKGSGLGMAISKEIIEIHKGKIYV
                     SSEIGIGTKIIIEIKQN"
     gene            complement(16799..17524)
                     /locus_tag="OE968_002562"
     CDS             complement(16799..17524)
                     /locus_tag="OE968_002562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012450879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCP7219837.1"
                     /translation="MENRVLIIDDEVEILKLLETVLKKEGLNNIYTAKTKKEGLELFK
                     SINPDLIVLDIMLPDGEGYDICKEIRKTSNSPIIFLSAKTEELDKLLGLAIGGDDYVT
                     KPFSPKEVAFRVKAHLRRLSYFSDAQNESKNLNNNEEKIISFGPYILNESRAELIKDG
                     KSIGLFAKELKILSLFAHNQNQIISKEKLWDKVWGEDYVGFDNTIMVHIRKIREKLED
                     NPSKPEYILTIKGLGYKLAVKED"
     gene            complement(17636..18409)
                     /locus_tag="OE968_002563"
     CDS             complement(17636..18409)
                     /locus_tag="OE968_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCP7219838.1"
                     /translation="MMYLVKAEMIKILKSKSVWIIWLFLIFFGFFLIRKFDVLDTYAD
                     IFYKIEGSIPLIGLIMFIITSGNYIKEYDSNMTGLINTTKKGKKSVVLSKLVANGLIL
                     SIINISFILLVGIRGFSFFDFKNLNESIHNLWYFGNSNLNLTVIQMYIIVILTTIFAS
                     FIFAQIGLTLSSIFKSAVIPFILGGLIMAIPYFSVGFIPDKAIKFMSVTPNWIMMSQQ
                     MVKYNVPSILIVFSIVISIILMIVLTKITYENFTSSKRF"
     gene            complement(18415..19302)
                     /locus_tag="OE968_002564"
     CDS             complement(18415..19302)
                     /locus_tag="OE968_002564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011948651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCP7219839.1"
                     /translation="MNKLEIENLSKIYGKKVANDKITVTLENGVYGLLGPNGAGKSTL
                     MKQITTLIKPDEGQILYNGEDIFKMDADYRNILGYLPQEFGVYKNFTAKEFLQYIGAL
                     KGLRGKYLNSKIGELLDLVGLYDVRNKSIGKFSGGMKRRAGIAQVLLNDPKIIVLDEP
                     TAGLDPQERARFRNLIAKMSRDKIIILSTHIISDIESVAKETIMIKDGKLLMKGTHKD
                     ILSHMENKVYNVQVKNECEVDDIQSKYKVVSIQSDINSIVLRIVSEDIPSEDNIQPVQ
                     AKFEDVYMFYFDLEDAREV"
     gene            complement(19316..20338)
                     /locus_tag="OE968_002565"
     CDS             complement(19316..20338)
                     /locus_tag="OE968_002565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219840.1"
                     /translation="MVNWEIKKLAKSKSMFISLGILVLILMISIFITPVLETESYYID
                     KEKGRIEDTRSGIDIGNEKFQNKINVLKQFSNQTDTGEFSKKIELMSKKKLDNLSVNE
                     YKDISFWKVFNYRVTNSLINVGMLIIISIIISNIYVDEVVTSVKDIILSSKEKKKALN
                     SKIFVALLVPLVIYSVYLMGIFIITCMQQGVPVNGDLESFRIVDNVVALKTNLSITKY
                     VILNIGIELLMFEGWAMIAIFGSFISKSSISSISFFIFIISITKIMSVIHILPKKLLS
                     VVSNVNYYDLIFGFNKIIGNYLGDIMIFKVNIDIVNIAIGLLMAILIGAMSLCFLVIK
                     SDYISR"
     gene            20913..21089
                     /locus_tag="OE968_002566"
     CDS             20913..21089
                     /locus_tag="OE968_002566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219841.1"
                     /translation="MFIGEIDKCTHILTAYISSSYDYCNFLDTQLDDFISEYGETVVE
                     TCLHQVLLLVSRYN"
BASE COUNT         7461 a         3361 c         2294 g         8322 t
ORIGIN      
        1 gagttttatt aataaaagta attacatata gattttaaaa tacttttatt aataacttaa
       61 aaataaaaaa ctgtcttgaa ataataaaat tatttcaaga cagtttttta taaatatctt
      121 taaaaagtta atcaatataa atattaagcc ctctttaatt tatctaaata gtaaacagca
      181 tttaaagctg ctatttgccc ttgaccagct gcttttatat aagaatatgg ttttccaaca
      241 caatctccag cagcaaagca tccatctata ctagtcttca tattattgtc aactttaata
      301 tgaatgccat caatctctat tccaggaacc aatgcacttg gagctgtact atcttttata
      361 acgaatactc catcaacttc aatgtggttt tctttaaaag atactttgtt tacaagttta
      421 tctccatcta tctgtactgg tctgtcatgt ataacttcaa tagaatcatc taggttatct
      481 gaacttctca taagattatc ttttttgtac ataggtataa aataagtctt tgaagtgagt
      541 tcacttaaaa aatttgcttc ttctttagat tcttcattat atcctataac tgctaccttt
      601 ttatttctat aaagtggtgc atcacatgta gcacagtagc ccacacctct tcctagaaat
      661 tcttcttcac ccttgattgg tctagtatac tctaccccag ttgcaaggat tacagtagta
      721 gcttcataca tatcatttcc agacattatt gtaaagtatt ctcccatagc ataaatatta
      781 tttattcttt tattttcaat tgaaatatcc atactatcta tatgtgattt aaacttgtct
      841 tttaattcat caccacttat atcataaaaa cctaaataat tatctattga aggagcttta
      901 acaagcttat tacttaaatt atcattacca aacatgataa ttgttttatt tcttattttt
      961 gcatttatag cagcagacaa tccagctgga ccactgccga ttatagctat atcatatctc
     1021 ataatactca cccatttttt ataaatatga ttttacttgc atttcaattt tgttctttgg
     1081 catgaatcca attaaagttt ctactggttt tccatcttta aatataatca tagttggtac
     1141 tgtagataca ttgaattgtt gagctatttc taagctctca tctatatcaa cttttacaaa
     1201 tctagcttta tccttcatct cttcacctaa ttctgcaaat acaggtccca acatgttaca
     1261 aggtccacac caagttgcaa agaaatcaac tacaactact cccttactac cttcaacact
     1321 acttctaaat tcagatgtat ttataacttt tgccattttt aaatcctcct attaaacttt
     1381 attatcccta tataattata ctatgaaatt tataaatata aatttacttt tataaggtct
     1441 ttttatattt tatactaatt agtataccca ttcttcattt ctaaaaacaa ttttttatat
     1501 ttttattatt ttaacttttt gggtattgac aattcaaatg tagttccaat atctacatca
     1561 gaagttacat ttatatcaat agataagttt aaactaatca tgcgagctat tgaaagtcct
     1621 attccagaac cttctaaatc tttatttctt acattttcac ttctaaaaaa tctatcaaat
     1681 ataagaggta tctcttcttt ttttatgcct ataccagtgt cacttataag taaagttacc
     1741 tcatcctcta tatcttcttt caattctaat gctatctcat cacccaattt tgtatactta
     1801 aaggcattat caatgaaaat taatataagc tgtcttaatt tatttttatc tgttattata
     1861 actttattct taagtttaga attaaacacg aatctttttt cctgaaactc agcaatgtca
     1921 atatagtctt ctgatatttc ttccaataac ttttctaaat ctatttcttc taaattaact
     1981 ttaacaatag agtcctcttt agtaagagac aataaatcag ttatcatttt tttaagtctt
     2041 ctagtttcct tcattgcagt agctattgtt tcaacttcat catttactgt actttctggg
     2101 gattttaaca tactttctaa ttttgatgaa actattgtta ttggtgttct taattcatga
     2161 gaagcatctt gtataaactt agcttgattt ttccatgctg tttctattgg aattaaagct
     2221 tttctagtga gatatacagc cacaaagtaa gtaattatta cagaaattaa tattccaatt
     2281 ataagaacag atgtaagctg tcttaaagaa ttcatctcag aatctatatt tctaattatc
     2341 tgtatttggt atctacctac atctacattt aattctctaa aagtatatcc attttctgtg
     2401 tatttaaaaa acgaattttt tttatctagt cttctatctg gaagtaactc atcaaaatat
     2461 tcattttgag tatagtaact tatccttcca tcttcataca catacaccat atctttagga
     2521 tctttcagtc ttattgggtt caaaaatgaa gttcttttaa attgagagac tatatattca
     2581 agttcatcat ttatctcact atcaattcca ctatatgtaa gtcccctaaa atatgagtat
     2641 ataaatatag aaaagattat taaaaaacta cctactacaa taatatacat ttttattaaa
     2701 tgatttttag tactggtaaa tacattctta tttatcatcg aatatatatc ctaccttacg
     2761 tttagtttta atatatttat catatccata tttacttagt ttttttctta gattacttac
     2821 atatacttcc actatttcaa tagtcgcatc tgaatcaatt ccccatattc tatcataaat
     2881 ctgctctttt aataaaattg aacctttatt taatacaaaa tactcaagca agttaaactg
     2941 tttgttttga agttttattt cttctttttc aatatacact cttttttcta gtgtatctaa
     3001 atataaagat ttaaattcta atccgtttct ttcttttatc tttccattag tccttaatat
     3061 agcgtatacc ctagctacta actcttccat ataaaaaggt tttgtcaaat aatcattagc
     3121 tcctatagta aatgcttcta ctttgtcatc taatgtttct tttgctgtca atataagtac
     3181 aggtgtatct atattattaa ctctcatttt ctttaggata tcaaatccat ttatattagg
     3241 aagcattaag tctaaaatga ctaaatcata tatattttga tttactaagt ataaagcttc
     3301 ttctccatct tcacactttt cagtttcaaa atgcttgcta agttcttcta ctacactttc
     3361 taaaagtatc ttattatctt caactattaa aaccttcata agtatcccct acctttattt
     3421 gtctatctta actttatgag attttaagtc aatatccaca ttggcttttt cttttatatc
     3481 atcatacgta tatcccacta tttcaacact ttttgccttt gttgaacaca atatatctat
     3541 atctgtctct tctgaaggct ttaaaatctt atatgatggc acacgattta ctgttaaata
     3601 ttctccattt tcattaactt ctgctgtctt aagaataata tttcctaaat cttttgatga
     3661 tgaatttttt acttttactt gatacgtaat tccctcattt gattcattta cttttttaag
     3721 ttctgatgta gatagcacct catactgact actattttct agcttaatat tattatttct
     3781 tatattaata gtattttctt ttaaattaac atacacaatc ttaccctctg cctcatattc
     3841 atatgcataa acttctacac cctttacaaa agttttatgc ccacattcta tgtaagcaac
     3901 tttcccaggc attaaagtca tgtccaacaa agccttacta tccgaagata taattttttt
     3961 attctcatca tattcattat atatcaattc aacattggat atattaaatg ttgaattatt
     4021 ttctaccttt gttgatgtat ctactttatc accttcatct atatttataa tttctgattt
     4081 tcctatattc aatacttttg catttccctc atctattttt atctcatttt tatcttctgt
     4141 ttgaatatca actgaatcag gctgttcatc tttttcacat gctgtcaaca taaaaataaa
     4201 tattgttaat ataatcatta gagaaattga tttttttact attttattca tattaagcac
     4261 ctcatatagt agtattttat agtagatttt tatacttttt cataaattct ttcaatgcct
     4321 gtgtaagtat ttgatgtttt tcaaaattcg aattactaca taatctttca aaatcattcc
     4381 atatttcttt atctatacgt attcttgttg tttttaattc atctatgtgt tcatcatcta
     4441 tatgtacatc ttttttatta gatacttttt taggctttat attgtaatct tttacttcta
     4501 aataccaatc atatacttca caaagcttat ctaaatcttc ttgagttata tttatttttc
     4561 tatctttctt aggcttaata ttttgttttg gctttgcatt ttttaaacct gtatcattaa
     4621 actcaatttg ttcaacactt ttacttaaag ccttttcatt agaaatcttt tttttggtgc
     4681 ttactttttt tctattactt atagtattct ttttactttt ttcatactcc ttagctttct
     4741 cttcttccaa gtttctatta tccaaacttt tattataatt taattcgtct ttaaatatgt
     4801 atttaccttt ttctgactta tatccttttt tatttaaaaa agttcttaaa gtactttgac
     4861 taatctttag attttgagct atctctgcaa atttaaatcc tttgctttga agttctaaaa
     4921 atttgtcaat tctgtcttca ttgttattca ttaatattcc tccgtcaaca tcttcttgtc
     4981 tttcttttca tacttcttat tatattcttc ttttctaaat ctactctatt tgattcaatt
     5041 attttttgta gcattttatt ataagtgaaa tcatctaaat tattattttt tatatagaga
     5101 aaagtttcct cttcacattt aataaaacaa attgatagca accatgccat acccatttta
     5161 acataatatt cttcactttg tatattatta cagtattcaa atatttcttt aatatgttta
     5221 tcatcaacat aatatattaa aaacataact aatgcaaatc taatttccca tggattcttt
     5281 gaataaacat attttttaag tatatcatac atattttctt tatatttttt catagacttt
     5341 aaatcagaac aaaatccatc gcaaactgac caattatcga ttttaggtat aaatcttttt
     5401 acatagtata aagtttcttc aaaattacta tttatattgc caattaccat accttgtagc
     5461 ctaacttctt catagtatgt atcctctgct acttctaaaa attccttcca attcccttgg
     5521 cttatttctt ttgataactt tcttaaatta ggaactctaa tacctattat attttctgtt
     5581 ccaggtataa gctttttatt aaaatctcta tattttatat cttgtataga catcatatat
     5641 tctaaaagtt cattataatc caatttattc cattttaccc tatcaaacat catttaattg
     5701 ctccttaatt ccttttttct tattgtaaca taaaactcta caaaaaaagc ttctaactat
     5761 tagaagcttt ttcaaaaaca taagaaactt ttcaatttta aatttaaact aaattaatgc
     5821 taatctccta caccaaaatc tgtattattg tataaaactt ctatatttgg attttcatcc
     5881 aagaatttat acttactaac aaaccatttc actaactctt catctctttt tatactagaa
     5941 gaattattta taaaaacatt cactgtcgct ttttcaaaag tatttaggat aatctctata
     6001 tctttatcta tcatctcttt tgtttgtcct tttattccaa ccataataca aggtgaatca
     6061 aaatattctt ttacatcttg tggagtctta aaatttgcat ttttatttaa aatattattt
     6121 ctaaaatcat tgtcaaaggt ttcaactcca attttaaata ccacaggaat ttcaaaatac
     6181 tctctcattt ccttaagcct atttttgtaa gaccaatgac tttctaaaaa taattttttt
     6241 atatttttct cttttataat acactttatt ttttctaaag tatccttagg taattcaaaa
     6301 cagcttccag aatttatgac ttcaagaact ccatatttcc cagttacgtt ttttaaaacc
     6361 tttagattta atttattcat ctcttcttct aaattagaat tatcatctat ataatcacaa
     6421 aaagaacact ttccccatat acaaggaaat cctttaagca gaacaatttc tctttgattt
     6481 ttatttgtta tctcactata tctatccatt ttctatctat tttcctccag tcaatgatac
     6541 ctttaaagtt tttggaactg catttaatcc taaattcact aaaacaactg ctaacagctt
     6601 atctccataa tcagtaaata cttgggttac aaacacacta aaaacatccc ccagtcctaa
     6661 cactttcaag atttgcacta tatatgatga acctgaagag gtcatacctc caaataaaaa
     6721 tgctgaaatt attgaactta ttatagatgt tggaatggca aataaaagta ctcctagtgg
     6781 agtttttaaa ccccttaaaa aattcttttt aaatgctatt ccagcaagta atccggttga
     6841 tatttgaact ggtgcaaaat agagagaata cacatcaaac gtaattccac ttattaaact
     6901 tccaaacaca cctgtaacaa cagcgtattt aggtcctaaa agtgaagcta tcattatagt
     6961 tcctattgaa tctaagtata caggtaatct taatcccata gctataaaag cgcctattat
     7021 atttatagaa ataccaaaag ctataagtgt aatagttttt acacatattt ttcttttcac
     7081 actatatcac tccttccaca gagtctataa tgtcttcata acctttaaaa agcctcttta
     7141 aaaacatgta cataaatttc ttctcatcaa cttcatttag aacaattgca ttaggatttt
     7201 ttttatagaa attgaaagaa tccactatag actgacccat agctattcca tcttctacaa
     7261 cttctacata tgattcaaat cctttacata tacttctatc tataaagtac gctactgcta
     7321 gagggtcatt tatcacacag ccaattattc cctcctgttc ccaatggaaa tcaatataaa
     7381 atctagttat ttcagttata tactttgcca tcttcttatc aagtctattt ataaactcaa
     7441 taatattagg agtaagtaca atttttctag ttacatctaa acctaccatg tggatttttt
     7501 tagataaatt cttgtaaaca taatctgctc catgtgggtc tacccaataa ttaaactctg
     7561 ctactggaga gcaatttcca tgaatcctaa atgctcctcc catagataca aactcatcga
     7621 gattttcaaa tgctttctta tctttaataa gtgctttagc tatatttgta agtggtgcaa
     7681 gtgctattat tgatactttt tcatgattat ataaagtatt tattataaaa tccactgctc
     7741 cattttttgc tttagctcct acaacctttt gataaaagtt ttctccaata ccatcttctc
     7801 catgtgtatc ttgagctgtt acaagttttc tttttagtgg tgcttcttct cctatatata
     7861 ctggaatatt tagtgaagaa cacatttgaa gtgtttttag tgcattttct gcacctatat
     7921 ttgctggaac atttccacaa catgtggtaa ttccaattac ttctagctct ggtgagttta
     7981 aagccagaag aattgccaaa gaatcatcaa ttcctgggtc acaatcaatt attacttttc
     8041 tcttttccat tttttatcct ccttgatttg tggtcgagga gaactacaca tcttttttcc
     8101 actttcaaaa aggtgtgtct aagggtatta attatatact gccactatat aattccttag
     8161 ttttttatac ttggagttct cgaacaagta cagatgtaaa atcatatttt taggctactt
     8221 actatagact cttaaaaact atagactgtt aaaaaatttt taaacatctg atttaatagc
     8281 tataaaataa attttatagc ataaaagaat ttattatatt ttaatgtatc ttattaaagt
     8341 ttatttagaa ttatgaacca actttaataa gatgtggcgc atttaaaccg attattatta
     8401 tacaataata tcttaaatat tacaattaat aacattaatt tattatccat aaaaatatat
     8461 taacttatat tatttaataa tttattgaca gtattaaaat taaattatac aataacagtg
     8521 taaattaact taacaccgtt aagcaaagag gtgattatat gagtatcaaa gaaagacgta
     8581 aaaatgaaaa agaagaaatg aagaaaaaga ttatggatgc tagcatcgaa attataaacc
     8641 aacatggata tgaaaattta tcaataagaa aaattgctac aaaaatagaa tattctccaa
     8701 ctacaattta tctttactac aaagacaaag cagagattat cagcgatatg accaataaac
     8761 tttataacac agtagaaagt aatgccattg acattatgaa taattgctca tcactaccaa
     8821 tagataaaca aatcatagaa attatgacta gctttataaa aactctttct agtgaaccag
     8881 agatggcaaa atctatcatg tatagtagaa tgaatattat atttgcatct gaaaatacaa
     8941 acaatacgcc tagcaataat ggtataaaaa tgcttgataa attcctttcc attggaattg
     9001 aacaaggaat attcaaaaaa aatatagata aaagctcatg gatgcttata agtgcattgt
     9061 taggattcgt tttatgtgtt gttgaaaata aactatattc tttacataat ttttctcaac
     9121 ttatagaaaa tttcttagat attttagtgg gaggacttta caatgaaaat tcgcaacaag
     9181 gctactaata aaaagaaaaa atatgtaaaa atatctattg ctctattctt tgtatttata
     9241 tgcattatta ttgtaattgt aagcaactta aagccagaaa acttggtagt aaaagatata
     9301 gatattaata atgttaaaaa tggcatttat actggaagtg ctgataataa cttggtaaaa
     9361 gctactgtgt ctgttgaagt taataatggt aaaatccaaa atattaatat cttaaaacac
     9421 gaccatcttt taggtaaacc tgctgaaaaa attacaacaa gtattattaa acaacagtct
     9481 ttagatgtgg atgctataac ttctgcaact tatagcagta atactatacg aaaagctgta
     9541 gaaaatgctt taagaaaggg agaataatta tgaatactat tattatatat tcaagtaaat
     9601 atggttgtac aaaagactgt gcaaatatac taaaaaataa actatcagat aatgtcacta
     9661 ttgttgatat taataataat aataaaattg agttatcaaa atttgataaa attattattg
     9721 gaagttctat atatgttggt tcagtttcaa aaaaaataca agtgctatgt aatgataatg
     9781 tagagttatt aaacaaaaaa caagttggca ttttcctttg ctgtggcttt tctgaacaag
     9841 cagataaata tttaaaatca aattttccat catccttatt agaaagtgca aatgctattg
     9901 gaatttttgg tagtgaagct cgattagaaa aaatgaaatt tttagataaa cttattatga
     9961 aggctgtttc aaaaggtaat tatgacagtt ttagaatatc acaggataat atagataatt
    10021 ttttaataaa tcttaatagc taaaataaaa ctaattattt ctatgataaa ttcttttatt
    10081 tataagtaat attgctcaaa atagtcttta aactttatca aaattttatt tttcttagtg
    10141 aaatctaatg aaactagcac ttaatatatg ctttattaat cataacaaat atgttttatt
    10201 aatcataaca aaaagagagt gtctaatgaa ctaaaaaatt cattagacac tctctttttg
    10261 tatgaaatca aatatatttt tatcatttca aaagtgaaaa atacacttgt ctctatgttt
    10321 ggcacattct ctttttataa tataatatct aatttaaaac ctatttcaaa tattgacata
    10381 tacttaaact atagacttac aaaatcaatt catattagct taaaatataa tctttgttat
    10441 tcaaattcct atacacaacc attatttact ttgatacttt aaaacatctt ccctattttt
    10501 tattaaattt tataataata gtcctattaa cgcaaatact ataaaaagag tttaacttta
    10561 tccattaaat aaatttaaat taaaacatat agaaatggaa ggagaacaat ttatgataaa
    10621 actaatcggt atattgatag ttgtaattgg atttatactt aaaattgaca cattatttac
    10681 tgtattatta gcaggagtgg caacaggaat tgttgcagga ttagatttta atcaaatttt
    10741 tacaatttta ggagattctt ttgtctcaaa cagaggtgta tcattattca tattaacatt
    10801 gccagtaatc ggtgtattag aaagatatgg tttaaaacaa agagctgttt ctttaataga
    10861 aaaattaaaa agacttacaa caggaaaagt acttactata tacatgatag ctagacaaat
    10921 agctggtgct ctatcaataa gaatgagtgg acatcctcaa tttgtaagac cacttgttaa
    10981 tcctatggca caagctgctg gtttaagtaa tagtgatgaa ctaaaagaat cggatgaaga
    11041 agccataaag gcattatctg ctgcatcaga aaactatgga aatttttatg gtcaaaactt
    11101 atttgcaggt agtagtggag tattacttat agcatctact ctgactcaat ttggatacaa
    11161 tgtaactgga cttaatatcg taaaggctag tactattatg gcagtaatag cacttgtagt
    11221 ggctacaatc cagtttacct tatatgataa aaaattaaac aaaagtcata aaaaatagtt
    11281 ttatttagga ggaataaaaa tgcaaaattt tataaacata tcattagaaa tcttttacgc
    11341 actaatggga tttttaatga ttgttatagc atataagtct tttactacca taaataacaa
    11401 taagaaatat ggtacatcat tattttggat acttatatca ctgccattca tatttggtag
    11461 attgattcca gccaatataa taggaataat attaatatta tctagtttat taacactttc
    11521 taaacaagtt gtatttgcaa agtatgaaga accagatgaa aattttggaa aagaacaagc
    11581 agacaaactt aaaaataaaa tatttatacc atcattaata ttagcatttg ctgcagtagt
    11641 agtagctatg agcctttcta attttgataa ttcttctcaa tttgcaatag gtgtgggttc
    11701 aataattgca ttaatatcag cccttataat aactaaggca aaacctgcta catcagttca
    11761 agatggctca agattacttc aacaaatggg acctgctagt atgttaccac aacttttagt
    11821 tgcattggga gctttattta ctcaagccgg agtcggtgaa gttatttcaa ccatgatatc
    11881 tggtgtagtc cctgctgata gcagattatt tggtgttata gcttatgtat taggtatggt
    11941 tatatttacc atgataatgg gaaatgcatt tgccgcattt tcagtcataa cggcaggaat
    12001 tggtattcct tttgtattgt ctcaaggtgg aaatcctgct ataattggag cattagcatt
    12061 aacagcagga tattgtggaa ctctacttac tccaatggct gctaatttta atatagttcc
    12121 agcagccttg ctagaatgta aaaatgatta tattgttata aaatatcaag ctccagttgc
    12181 tttggtatta attatagccc acatattagt aatgtacttt ttaggatttt aatataatta
    12241 ggaggtaaaa taatgaaaat tttgttaaca ggatttgacc catttggtgg agaaccaata
    12301 aacccagctc aagaagcagt tgaaagggtc aataataata taaacggtgc agaaatcata
    12361 aagataacta taccaacagt tatgacaaaa tctgttgaag ctatagataa agctattcaa
    12421 gagcacaatc cagatatagt aatatcagtt ggacaagctg gaggtagatt tgacattaca
    12481 cctgagagag ttgctataaa tatagatgat tttagaataa aagataatga gggtaaccag
    12541 gttatagata ctattataaa agaagatggt gaacctgcat atttttcaaa attgcctgta
    12601 aaagctatgg taaaacatat gaatgaaaat aaaattccag ctagtgtttc aaacactgca
    12661 ggaacatttg tttgcaatca tgtgatgtat ggaattcttt atatgataga caagaaatat
    12721 cctaatataa ggggtggatt tatacacatc ccatatacaa cttcacaagt aatagataaa
    12781 aaaaatacac cattcatgtc tttagaagaa atagtaaaag gcttagaatt agctatagaa
    12841 gcttgtatta tatataaaga agatgtaaaa gaaattggtg gtgaaatttc ataataaatt
    12901 ttttagtatt tttataaatt aaaaatacta actattaatt taaatataga ctgtgagtag
    12961 attattcaaa caattttact cacagtcttt ttatggtatc tacagataca aaattaaggt
    13021 ctattcctct ctccccactc acacattgca tctaaaattg gaatcagaga ttttcccctt
    13081 tctgatagac tatattctac cttaggaggt atttgaggat attcagtacg aataatcaag
    13141 ttatctgctt ctaattcttt taatgataaa ctcaaagttt tataggagat agtatttata
    13201 taacgtttta atgcattata tcttacaact tcaaattcta caagacagta aagaattatc
    13261 atcttatatt taccactaat cagtgaaagt gtataactaa atcctgtttc acttaaatct
    13321 gtatttgata tacagtctat actcatatat tacactctcc ttttggttag tattgaacaa
    13381 aaatgtgcgt acttgttttt agaataattt ataataaaat tatagtgtaa gaataattga
    13441 aagtcaattt tataatagga ggtgtattta ctaaaaaaaa agttatttta aataggattc
    13501 taagattaga catttctata taaattgata atattcatga aaatcctatt ttataaaaaa
    13561 taatatctct tagaaaatct attaaataaa attcattgga ggaaatttat aatgaaagtt
    13621 ttattgataa acggtagccc aaaccaatat ggatgtactt atacagcact aaatgagatt
    13681 actaaagtat tgagtaaaca cgatattaaa acagaaatac tgtatttagg taaagaaaca
    13741 atcccaggat gtattagttg cgcatcctgt tttgaaactg gaaaatgtat tcgaaatgat
    13801 aaagttaata aattgattga agatctggat aatattgatg gtattattat tggttctcct
    13861 gtttactttt ctagtgcaac tggtcaatta acttcttttc ttgaccgtct atttttcata
    13921 gctggaagtc gcatggctac aaaattaggt gcttcagttg tgtcatgtag acgtggtggt
    13981 gcaagtgcaa catttgacca actaaataaa tatttttcaa tcagcaatat gcctattgta
    14041 tcatcacagt attggaacca ggtacatggc tttactccag aggatgttat gaaggatgaa
    14101 gaaggattac agactatgcg aactctagga gaaaacatgg catggcttct taagtgtata
    14161 tcagcaggta aaaaagctgg aattaaagaa ccacaatatg aagaaacaat tatgactaat
    14221 tttataaaat aaataaaaaa tgtactaata ttaattaaaa caaaacacta atttataaat
    14281 aaaataagca taaatgtagg ataaaaagca ctaaaacaga ggtattgaat tttatatcaa
    14341 acctctgttt tattattaca ttaataacca aaccatgtat aacatcatat atttctaaat
    14401 aaattataat attatattct aatgttattg aaattacaat aactgaattt ctgctcataa
    14461 atttaaatat tctacaaatc tcatctaaat aacaatttta atagacctaa aacaatcctc
    14521 atactgttca ttttgtatta aaaatatcac ttacaatcaa aaaccattta ttaagtatat
    14581 tcctaagata tacaatatat atacatggat tggatagtat aaataaaata aatacttcat
    14641 actcttccct ttttctccat tgtaaagtaa cattaaaggt agagaagcaa tcatcatcca
    14701 ttggtaattt tgtaaaatag aattttttaa actataatct ccatttgaca ttgttgtaaa
    14761 tataaatata cacattaaaa cataacaaat actcaaactg aactttttac ctctacacaa
    14821 ataaaaaata atcccaagta taatccaaat tggtccacct tctactaaaa atggtactgg
    14881 taccaaaatc ataaataaag caataactct gttagtgact ttaaaaagta aagctactgt
    14941 aaatattcct aaaattatag gaatgattat catcaataat cctataataa aatatttaat
    15001 ttctttctct tttctaaatt tctttatgaa ctctattgct tgtaaataaa tcgctattaa
    15061 aaataatgtt gaaaaaatgt tatttataat tatagctcct tctggatgtg aaaatacatt
    15121 attaattatt tgatttccta tagccataat aacagaccaa atatacaatc tacttatata
    15181 tttttttctg ttactagtgt gataaaatcc ttcaacagcc atgaatataa acagtggtgc
    15241 tgatattctg cctacccaat gaaaccaaat tggtatttgc attgtttgtg gcataaatgc
    15301 tgctatatgg tcaaatgtca taaatattaa tgctaaaatt ttaatagtaa acccacttat
    15361 acctttttta aaaaaatcca tatcatatct cctaattttg ttttatctct ataataattt
    15421 ttgttcctat tccaatttca ctacttacat aaattttacc tttatgaatc tctattattt
    15481 ctttagaaat agccatacca agacctgaac ctttatgcat ctcacctgta ttagtacctc
    15541 tataatattt tttaaaaata tgtttcaaat cacttttgct tattccaatt ccattatctt
    15601 ttattataat ttctatatta tcttttttta caatttctac acttatcaaa gttccttcgc
    15661 tattatgaac tattgaatta aatataagat tggttatagc ccttctgaat aagattgaat
    15721 ctacatatac ttcaattaaa tcttcattac tttcaaattc aatattccta tttttatatc
    15781 tattatcatt taaaatatca attattatat ctctgactaa actgactaaa tttatttttt
    15841 tcttgtccag aactatagta ttatttttta atcgagtaga taaatttaaa tcatcaacta
    15901 aatcttttat atacttagac ttattatata taatttctgt atactcttgt atttcatctt
    15961 cttcaaactc ataatctttg tcattaatta tctctgcata cccttgtata gatgctagag
    16021 gtgtctttat atcatgtgtt atatttgcca gccattcctc tctcaactct tcattttctt
    16081 ttctctcaac ttcatttact cttaaagtat cagctaacat atttatattt ttaaaaactt
    16141 cttcatatat acctctgtcc ttaagatata aactataatt tccattagcc atagtctcaa
    16201 tactccatag tacgcttgaa attggttttg taagttttct actaaataaa tatcctacac
    16261 ctaaagctac cacgctatca attactagtg ttataatgat aactttattt aaagtttttt
    16321 taatgttatt ttgagaatag gttaaaatta ttcttgatat atctctacta ggtataccta
    16381 ctattatgtt taaatgtttt ttgtttaaat atttttctag tacaaaatta acatactttg
    16441 tttctatata cttgtaatta ttcaccattt gaaagggtgt atattttttt ggagtatcct
    16501 ttggcacatt tactccataa acttcctctc ctaaatcatt taaaacctgt atccaggaat
    16561 ttgatttttc taatttttca gctccaatct tagatagttt aaattctcca tctttttcat
    16621 ataaatcttt ttcaaaagaa cgtgcaaatt cttcaggatt atttccagaa tctacaactt
    16681 taaaaaagct attagttgaa atcacataca atatagatat gatatttata attactactg
    16741 atatagctac aaacacaatt gtaaatataa aatttctagt aatcttccac ttcatattct
    16801 aatcttcctt tactgctaat ttatatccaa gaccttttat tgtcagaata tattcaggtt
    16861 ttgaaggatt atcctctaat ttttccctaa tttttcttat atgaaccatt atagtattgt
    16921 caaatccaac ataatcttct ccccacactt tatcccatag tttttcttta cttataattt
    16981 gattttgatt atgtgcaaat aaagatagga tttttagttc ctttgcaaac agtcctatag
    17041 attttccatc ttttataagt tctgccctac tttcatttaa tatatatggg ccaaatgata
    17101 taattttttc ttcattatta tttagatttt tactttcgtt ttgagcatca ctaaaataac
    17161 ttaatcttct caaatgcgct ttaactctaa aagccacttc cttagggcta aaaggttttg
    17221 taacataatc atctcctcca atcgctagtc caagtaactt atctaattct tcggttttag
    17281 ctgataaaaa tattattgga gaattggagg tttttcttat ttctttacaa atatcataac
    17341 cttcgccatc tggtaacata atatccaata caatcaaatc aggattaata cttttaaata
    17401 attctaatcc ttctttttta gtttttgcag tatatatatt attaaggcct tcttttttta
    17461 ggacagtttc taaaagcttc aatatttcta cttcatcatc tattattaaa acacgatttt
    17521 ccataaacaa cctcctgtaa taatttacat atatattagc atatatttta tctaaaattc
    17581 atttatctta tttttaatta aactaaaata taaataaaat tactattatt tttagttaaa
    17641 accttttgct tgatgtaaaa ttttcatatg ttattttagt taacactatc attaatataa
    17701 ttgagattac tatagaaaaa actatcaaaa tacttggtac attatactta accatttgtt
    17761 ggctcatcat aatccaattt ggagtcactg acataaattt tatagcttta tctggtataa
    17821 aacctacact aaagtatgga attgccatta tcaatccacc tagtataaat ggaattacag
    17881 ccgatttaaa tatagatgaa agtgttaagc ctatttgtgc aaatataaaa gaagcaaaaa
    17941 tagtagtcaa tataacaatt atatacattt gtattactgt aagatttaaa ttactatttc
    18001 caaagtacca taagttatga atcgattcat ttaaattttt aaaatcaaaa aaactaaaac
    18061 ctctaattcc tactaacaat ataaaagaaa tattaataat agataaaatt aatccattag
    18121 ctactagttt tgataatact actgattttt ttcccttttt agttgtattt attaaacctg
    18181 tcatattaga atcatattct ttaatgtaat ttccagaagt tattataaac attatcaaac
    18241 ctattagagg tattgagcct tctatcttgt aaaatatatc tgcataagta tctaaaacat
    18301 caaactttct aatcagaaaa aatccaaaaa atattaaaaa cagccaaatt atccaaacac
    18361 tctttgattt taatattttt atcatttcag ctttaactaa atacatcatt tctactacac
    18421 ctcccttgca tcttctaaat caaaataaaa catgtataca tcttcgaatt ttgcttgaac
    18481 tggttgtata ttatcctcgc ttggaatatc ctctgaaaca attctaagta ctattgaatt
    18541 aatatcactt tgaatactta caaccttata tttagattgt atatcatcaa cttcacattc
    18601 atttttaact tgaacattat atactttatt ttccatgtga cttaatatgt ctttgtgtgt
    18661 tcctttcatt aggagtttgc catctttaat cattattgtt tcctttgcaa ctgattctat
    18721 atcggaaatt atatgagtag aaagtattat tatcttatct ctagacattt ttgctattaa
    18781 attcctaaat ctagctcttt cttgtgggtc aagacctgct gttggctcat caaggactat
    18841 tatcttaggg tcgtttagta aaacttgtgc tatcccagct ctcctcttca tacctcctga
    18901 aaattttcct atagacttat ttctcacatc ataaagacct actaaatcta ataattctcc
    18961 tatcttacta tttaaatatt ttccccttaa accttttaaa gctccaatat actgtaaaaa
    19021 ttcttttgct gtaaaatttt tataaactcc aaattcttgt ggcaaatatc ctaaaatatt
    19081 tctataatca gcatccattt taaatatatc ctcaccatta taaagtatct gaccttcatc
    19141 aggttttatc aacgttgtta tttgtttcat taatgtagat tttcctgctc catttggtcc
    19201 tagaagacca taaactccat tttctagagt tactgtaatc ttgtcgtttg ctactttttt
    19261 accatatatc tttgaaagat tttctatttc taatttattc atcttaactc cccttttatc
    19321 tacttatata atctgatttt attactaaaa aacataatga catagcacct atcaatattg
    19381 ccatcaaaag tcctattgct atattgacaa tgtctatatt cactttaaat atcataatat
    19441 cacctagata atttcctatt attttattaa aaccaaatat caaatcataa taatttacat
    19501 ttgatacaac tgaaagtaat tttttaggta atatatggat taccgacatt atcttagtta
    19561 tagatataat aaatataaaa aaacttattg aagatattga agacttactt ataaaagacc
    19621 caaatatggc tatcatggcc catccttcaa acatcaaaag ctctatgcct atatttaata
    19681 ttacatactt tgttatactt aaattagttt tcaatgcaac tacattgtct actattctaa
    19741 aagattctaa gtctccatta acaggtactc cttgttgcat acaagttata ataaatattc
    19801 ccattaaata aacagaataa attactaatg gaactaataa agcaacaaat attttagaat
    19861 ttaatgcttt tttcttctct tttgatgata gtatgatatc ttttaccgaa gtaacgactt
    19921 catctacgta aatattagat ataattatag atataatgat taacattcct acatttataa
    19981 gtgaatttgt aactctatag ttaaatactt tccaaaaact aatatcctta tattcattca
    20041 cacttagatt atcaagtttt ttctttgaca ttaattcaat ttttttagaa aattcacctg
    20101 tatctgtttg atttgaaaac tgctttaaaa cattaatctt attttgaaat ttctcattac
    20161 ctatgtcgat accacttctc gtatcttcta tacgtccttt ttctttatct atataataac
    20221 tttctgtttc taaaacaggc gtaataaaga tactaatcat tagtattaac actaatatgc
    20281 ctagagatat aaacatactc ttagatttag ccaatttttt tatttcccaa tttaccaata
    20341 tatttctcct cctaaatcat tttaattaca catatatatt aaaacttaaa tcttatataa
    20401 atataatact aaccttaaat aaagcttaaa ttattttata atttataggt gtgtttatta
    20461 ttggagttac atttattatt tttctgggaa attatacatt ttcaattatt tttattattt
    20521 ttgatatttt tattgattgg aaattttatt gttgttcaaa ttgtagttat tctttaaatt
    20581 taaagatgga gttttttaag aatagaacct actgtcctta ttatggaaag attattaaat
    20641 agttgcatat aactttattt atcttgaatc ttatttttaa aaacaattat aattttagaa
    20701 tattttctat tctcaaacaa gcatgttgaa taatgaagca tcttctagta ttatatactt
    20761 gtagaataaa actaaattgg taaaactggg aatatttaac cttaaggagt taagttatag
    20821 aaactagtac taaaaaattt tataaattat gttaattgac taatagaatg cgacttttta
    20881 tttttactaa attttttagg gggatggata atatgtttat tggagaaata gacaaatgta
    20941 cacatatact aactgcttac atcagtagtt catatgatta ttgtaatttt ttagatacac
    21001 agttagatga ttttatatca gaatatggag aaacggtagt tgaaacctgc ttacatcaag
    21061 tcttattatt agtaagtaga tacaattaaa actaaatttt tctagaaaaa cctttttaga
    21121 tttatctact ctaataaata tataattttt tgtactttat aagtaactat aacttctgct
    21181 aaagtaaaga tgtattggga gtacatcttt actttcccat tatagaagtt aaaagcatac
    21241 accataaaat taatcatcca atacaaatta tatatttcct atgtctaact taatttacaa
    21301 gaatcattct atatgcatat tctgcaatcc actaaacatg gctctaaacc tttactattt
    21361 tatacattct ctataaatca tacaaatcat atataaaatc cccctaatat gtttaaacca
    21421 cctataaaat aacaccaa
//
LOCUS       DAJMZY010000074        21066 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.074, whole genome shotgun sequence.
ACCESSION   DAJMZY010000074 DAJMZY010000000
VERSION     DAJMZY010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 21066)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21066)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21066
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.074"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            330..1448
                     /locus_tag="OE968_002567"
     CDS             330..1448
                     /locus_tag="OE968_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCP7219842.1"
                     /translation="MIAVKKAYKFRMYPNKKQQELINKTFGCCRFVYNKYLAKRIDVY
                     KSDKETFTYKQCSSDLTNLKKELKWLKEPDKFSLQNALKDLDNAYKKFFKEKAGFPKF
                     KSKKINRFSYKTNFTNGNIMYCGQYIKLPKLGMVKIRDKQVPQGRILNATISKEPSGR
                     YYVSLCCTDVDIEVFENTNNHIGLDLGIKEFCISSCGDFIENPKYLKKSLNKLAKLQR
                     ELSRKTIGSLNRNKARLKVAGLQEHIANQRNDFLQKLSTKLIKENDIICIEDLQVKNM
                     IRNRKLSRLISDVSWSEFIRQLEYKANWYGRKIVKVGKFFASSQICNKCGYKNEEVKD
                     LNIREWICPSCNETHDRDINASINILKEGLRLITIQNK"
     gene            1566..1871
                     /locus_tag="OE968_002568"
                     /pseudo
     CDS             1566..1871
                     /locus_tag="OE968_002568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438308.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
     gene            1884..2789
                     /gene="truB"
                     /locus_tag="OE968_002569"
     CDS             1884..2789
                     /gene="truB"
                     /locus_tag="OE968_002569"
                     /EC_number="5.4.99.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HCP7219843.1"
                     /translation="MNKIISILKPTGMTSHDVVSRVRKILNIKKVGHTGTLDPDASGV
                     LPICIGKATKVCEVILNKDKSYICELTLGISTDTYDASGEILKKVDDFKFSNEDIERA
                     FDTQRGEINQLPPIYSALKVNGKRMCDLVRSGRQSEITLKTRRVNIKDIKILSIKGNK
                     VMFYVECSKGTYVRSICHDIGEYLGCGAHMSFLNRTSSGKFDLDNSITLEELELFYEN
                     KTLDKYLYDIDYVLDSFNYVVLNPNAIKYYSNGGSIDDKRFLKNNFDKDDEFVRVYST
                     DNFLGLGKLSKHNNTISVKSDKMFI"
     gene            2920..3849
                     /locus_tag="OE968_002570"
     CDS             2920..3849
                     /locus_tag="OE968_002570"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HCP7219844.1"
                     /translation="MVIIKSIKEIANIKESVITIGNFDGVHKGHQVLIGKTVEHAKKE
                     NIQSIVFTFANHPVNYFRPNSTKNIISNDDKIKLLEDLGIDIVVIIPFDEYMTKIPAK
                     DFVDEILVKKLKAKKIVIGHDFTFARAKEGNVNLLKSLEHEFGFEVEVIKPIKINDVR
                     VSSTYIRSLVSQGDMANVKEYLGRNYKLEGCVIHSKHLGRTIGFPTANIDLKNNMLVP
                     KRGIYASIVHIGDETYFGATNVGYNPTVNGKTLSIETNILEFDRDIYGENIIVEFLER
                     IRDERKFNSIDDLKNQLYNDTNYVYENYVCKNK"
     gene            3953..4210
                     /gene="rpsO"
                     /locus_tag="OE968_002571"
     CDS             3953..4210
                     /gene="rpsO"
                     /locus_tag="OE968_002571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002843739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HCP7219845.1"
                     /translation="MINKSEIIKEYGRAEGDTGSPEVQIALLTARINELNGHLKTHKK
                     DHHSRRGLLKMVGRRRNLLAYLKEKDLEGYRALIAKLGLRK"
     gene            4450..5295
                     /locus_tag="OE968_002572"
     CDS             4450..5295
                     /locus_tag="OE968_002572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HCP7219846.1"
                     /translation="MKIKLVCDSLCDIPDEISEKDYIEIVPLTVIFNDREYIEGVDIK
                     KEEFYKKVKEIKQIPKTSQATYMEFKEVFDKFITEGYHIICMTGAANASGTFQSAMIA
                     KNDVNENEKIHIFDTRNLSLGSGQYVIKACELLEEGLGFEEIIDELENTRSSVRLLFA
                     PYTLDFLKQSGRVPVATALIGNMLNIKPIFFFDNGEAKLVNKVRGIKNIASKLVDIIL
                     EMNEGSLEGKIVTIGCGDNLHDCEILKDEVNKRIKARRVLFTRGGVSICSHTGPDILA
                     ISCSN"
     gene            5420..7531
                     /gene="pnp"
                     /locus_tag="OE968_002573"
     CDS             5420..7531
                     /gene="pnp"
                     /locus_tag="OE968_002573"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HCP7219847.1"
                     /translation="MFEHKIFKMDFAGRELSVEIGKICEMASGSCIVRYSDSMVMVNT
                     TKSAKPRDGIDFFPLSVDYEEKLYSVGKIPGGFLKREGKPSEKAILTSRLIDRPIRPL
                     FPKGFRNDVQVVATVLSVDQDCTPDIVAMIGSSIALSISDIPFNGPTGSVCVGLVDGA
                     FVVNPNAEQREKSSMHLVVSGTKEAIMMVEAGADEVPDEVMLDAILFAHQEIKKIVEF
                     IEGIVAEVGKEKMPVELYHAGEEITQLVREFATDKMKKAVQTFEKLERMENMDRVKEE
                     TLAHFEETLEDFEDFVGDIEEVLQDIIKEEVRKLIVHENVRPDNRKLEEIRPIWCETG
                     MIPRAHGSAIFTRGQTQVLNVATLGALGDVQKLDGLDEEENKRYMHHYNFPAYSVGEA
                     RPSRGPGRREIGHGALAERALLPVIPSQEEFPYAIRLVSEVLSSNGSTSQASVCGSTL
                     SLLDAGVPIKDMVAGIAMGLIKHDGKVAVLSDIQGMEDHLGDMDFKVAGTEYGITAIQ
                     MDIKIDGIDKEILQRALKQAKEGRIHILGEMRKTISQPKPELSPYAPKIVKMQINPDK
                     IKDVIGPGGKIITKIIDETGVKIDIEQTGEVFISGIEIDMIKKAQELINNIVVEPEVG
                     KTYKGKVSRIMNFGAFVEILPGKEGLLHISHIAHERVAKVEDVLNIGDEVEVKVTEID
                     EKGRVNLSRKVLLPKPEHKNK"
     gene            7797..8540
                     /locus_tag="OE968_002574"
     CDS             7797..8540
                     /locus_tag="OE968_002574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HCP7219848.1"
                     /translation="MIMMVLNKSKLKKIIILILVVLLVLSGGVMVLKLFNNKPVFNLF
                     NGVDLPYERGTKDKSGYVALTCNIDLGWETEYVESILETLKKENVKITFNVTGKWAEK
                     NKDELLKIKKQGHEIGNHGYKHLDYSTLSYEDNYEQIETSKKIIEEIIGEKTKFFQAP
                     AGSFGPETVKAAKALGYTSIKWDADTIDWKYKDQPEVIIDRMKKKDIKDSSIILMHPT
                     NATTKCIDDIIAIVREKGLKPGKLSDVFK"
     gene            8698..9945
                     /locus_tag="OE968_002575"
     CDS             8698..9945
                     /locus_tag="OE968_002575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HCP7219849.1"
                     /translation="MYKTKILENGLTIIGEEIPYLKSITLGIWINAGSRIEEAQVSGI
                     SHFIEHMMFKGTKNRTSKEIASSIDNLGGQINAFTSKECTCYYVKLIDEHIDTGIDVL
                     SDMILNSKFDKNDIDKERLIILEELKMYEDSPDDLSYDLLVENIYANDGLGMNIIGTK
                     ESLYNITRESMLEYLNKYYIPNNAVISIAGNFNFDDMVEKIKSKFGHWEKKNLSIDIS
                     EAKFNPCFISKNKDTEQVNLAMCLKGIPFENDEEVYSMAVVNNIFGGSISSRLFQKIR
                     EEKGLVYSIYSSQTLYRKCGELGIFASMSTENLQDVYNLIKKEIENIRENYLTEKEIS
                     ESKEQLKGNYILDLESTSSRMMSTGKSMLLSKKVKTTDEILECINNVNINSIKKVVDK
                     VFNIENIGTCIVGRDVEKILHLD"
     gene            9980..10225
                     /locus_tag="OE968_002576"
     CDS             9980..10225
                     /locus_tag="OE968_002576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlmC/YmxH family sporulation protein"
                     /protein_id="HCP7219850.1"
                     /translation="MNLSEIAGKEIVNLVTGERLGVIGECDLILDETTGDILALLIPK
                     EKGFFARRKDKSFLEVPWRNVKKIGNDMIIIEYEGYI"
     gene            10235..11458
                     /gene="dapG"
                     /locus_tag="OE968_002577"
     CDS             10235..11458
                     /gene="dapG"
                     /locus_tag="OE968_002577"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HCP7219851.1"
                     /translation="MSILVQKFGGTSVESYEKMNEVCKIVKAYKKNDEELQLVLVVSA
                     MGRKGAPYATDTLINLCSAVNDEPSKRELDLIMSCGEIISGTILANLLNAQGIDSVFF
                     TGQQAGIITSDEYSNAKIKYINPKKVKRALDDGKVVVIAGFQGVTDDGEITTLGRGGS
                     DTSAVAIGKALECETVEIYTDVDGIMTADPRVEPNAKVLSFIDYEEVFQMADKGAKVI
                     HPRAVQLAKSGNITLAIKNTMNPTFEGTKIGSLCRHLEDNIEYEQERDFKVAVANKDS
                     VAQVKIKSAEEVFTEVLNEIEKKLITIDMINFFISEKAFVVEDADIKSLKEILDKFEL
                     DYEVNRDCAKVTLICSRIADEMSGIMSKVVRGLSKAGVSLLQTSDSNMTISCLVSEED
                     MHTAVHAIHQQFYLK"
     gene            11571..12305
                     /locus_tag="OE968_002578"
     CDS             11571..12305
                     /locus_tag="OE968_002578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit"
                     /protein_id="HCP7219852.1"
                     /translation="MKDYREDNEKFDKDNCSEESSCEERECIKQFGTNEMPPQPPKDI
                     QCITIIGEIEGHFIGNPQKKATKYEHIIPMLYSIEESNDVKGVLVVLNTVGGDIEAGL
                     AIAELLNSTSKKVVTLVLGGSHSIGVPLATAGDYSFIAPTATMIIHPVRTTGLVIGIN
                     ETFEYFKKMQDRIIQFIIRTSNIKKDVLEKLMHEKDELVSDVGSVLIGKEAVDYGLID
                     EVGGLKEALKKLRELIKESEEEKNND"
     gene            12428..14839
                     /locus_tag="OE968_002579"
     CDS             12428..14839
                     /locus_tag="OE968_002579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HCP7219853.1"
                     /translation="MATKKKKKKKVNTLSFNAEYHNLITIFIGVFLLYSLNSNSMGWI
                     PVLMQNLFKGLFGGLSIAIPFIVIITGLLGFFDGNEYIYRLRKTKLYYIIILFIFVFY
                     GLLNAGTLPVDSPLKGNMFDDVMKLGVSGQGSGLIATTIAYYMSKIFGIAGGWLISIF
                     ALILSVMFIFNISIKDLVSNAKSKSKASKDSNLTFKDKIANMKKSAIDMMTDEVDDTT
                     INKKPGFFKGLMSKGLNNDDEEDEYFEEENSDGVDDKTIKIVGFNKAEDEYLEILEGT
                     QSMPELDVLKELQKATNENPVVDTKPEKKVDIAKPNLNIEKTQPMSIVAEPVNEDYSN
                     YKKPSIELLNKVNKKSDENGKKKVLKNASLLEKTLSDFGVEAKINQVTVGPTITRYEI
                     QPSPGVKVSKIVNLTDDIALSLAAKSIRIEAPIPGKSAIGIEVPNEEAQMVGVREVLE
                     SEEFNNFNSPLAMGLGKDVAGKIIIGDIGKMPHLLIAGSTGSGKSVCVNTLISSILYK
                     ANPDEVKLLLIDPKVVELANYNGIPHLLIPVVTDPKKAANALNWAVTEMNRRYKLFAD
                     AQVKDVTSYNEKAEEKLPKIVIIIDELADLMMASANDVEDYICRLAQMARAAGMHLIV
                     ATQRPSVDVITGVIKANIPSRIAFAVSSQTDSRTILDMGGAEKLLGKGDMLFYPLGAA
                     KPVRLQGAFISESESEKVIDFVKSQVKDGIKYEEDIIETISKVNTSKGSDEDEFLSEA
                     IEFVVESGQASASMLQRRFKIGFNRAARLIDSMEERGIIGASEGSKPRKVLISKQDLQ
                     NLEGE"
     gene            14842..15900
                     /gene="mnmH"
                     /locus_tag="OE968_002580"
     CDS             14842..15900
                     /gene="mnmH"
                     /locus_tag="OE968_002580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-selenouridine(34) synthase MnmH"
                     /protein_id="HCP7219854.1"
                     /translation="MSVIKIEKALKLDKVIFVDVRTEGEYEEDHILNAINMPLFKNNE
                     HNEVGTIYKMQGKHEAIQKGFDYVSYKLKDIYLQAAELALNYDNIVIYCARGGMRSGS
                     IVNLLSSLGVNVYQLEGGYKAYRNFVLEYLRHVMDTKNFVSVHGLTGTGKTDLLHLLD
                     EKGIDVLDLEGIAKNSGSTFGFITFDKKPPSQKNFETKLFESIFFSKENYIFVESESK
                     RVGSVTVPNEIFEAMTREGHHILLECDIENRVDRLCRDYIYDKDEGNILILKECINKF
                     RKRLGNKVVDDYIDLLESGEYKELVKRYLLEYYDPLYMHSVEKYKYSKIINFNDTQKA
                     LEDVIDLYESILEGESEC"
     gene            15894..17228
                     /gene="rimO"
                     /locus_tag="OE968_002581"
     CDS             15894..17228
                     /gene="rimO"
                     /locus_tag="OE968_002581"
                     /EC_number="2.8.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12 methylthiotransferase
                     RimO"
                     /protein_id="HCP7219855.1"
                     /translation="MLKIALESLGCSKNLVDAEIMMGILNNKGYKLIGDFEEADVIIV
                     NTCGFIESAKQESIDTIINFAELKKTGNLKLLIVTGCLAQRYSEELKTEIPEIDAIVG
                     TGSYQNIDKILKELSEMHQIVSLNDIEFVFNEDLPRYISTPSYMAYLKIGEGCSNNCT
                     YCIIPKLRGKYRSRKFEDIIKEAKKLAESGVKELVVIAQDTTKYGFDLYGKERLSELL
                     EELAKIDGFKWIRVMYSYPESITEELIQVIKKYDNICSYFDMPIQHASNNILKLMNRK
                     TTKEDILNKINLIRSNIPDAILRTTIIVGFPGETEDDFKQLVDFVEEVKFDRLGAFAY
                     SREEDTPADRLPNHIDEEVKIQRRDTLMMIQQKISEELNDKKIGKTYEVLIEEQIEDN
                     VYTGRTQGDAEEIDSIVYVKSVDNLEVGEFVSVQINDAMEYDLMGDVLYELA"
     gene            17215..17757
                     /gene="pgsA"
                     /locus_tag="OE968_002582"
     CDS             17215..17757
                     /gene="pgsA"
                     /locus_tag="OE968_002582"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HCP7219856.1"
                     /translation="MNLPNKLTLFRIFLIPVFVLIMLLNVPNKFLIACIIFIIASITD
                     ALDGKIARKYNLVTDFGKFMDPLADKLLVISALTCMIEDHLVSSWMVIIIVARELTVS
                     ILRAIAAADGKVIAAGNSGKLKTITQMVSIVFLLLGAQFENVLILNIGEILILIATLL
                     TLYSGWEYLYKNKELFMSSK"
     gene            18045..19091
                     /gene="recA"
                     /locus_tag="OE968_002583"
     CDS             18045..19091
                     /gene="recA"
                     /locus_tag="OE968_002583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HCP7219857.1"
                     /translation="MSVDQEKLKALNEALGKIEKDFGKGSVMKLGEATSMSIDVISTG
                     AIGLDIAIGIGGLPRGRIVEVYGPESSGKTTVALSCVASAQKDGGIAAFIDAEHALDP
                     VYAKALGVDVDNLIISQPDTGEQALEIAEALIRSGAIDIIVIDSVAALVPKAEIDGDM
                     GDSHVGLQARLMSQALRKLTGSIKKSNCVAIFINQLREKVGIMFGNPETTTGGRALKF
                     YSSVRLDVRKIDTIKQGDKVIGSRTRVKVVKNKVAPPFKQAEFDIMYGEGISKIGDLL
                     DIAADVDIVKKSGSWYSYNDTKLGQGRENVKKFLEDNLDLTTEIDEKVRAFYNLNEEH
                     EESGISVSKEIVEE"
     gene            19267..20808
                     /gene="rny"
                     /locus_tag="OE968_002584"
     CDS             19267..20808
                     /gene="rny"
                     /locus_tag="OE968_002584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HCP7219858.1"
                     /translation="MDVIDSVVMIVIGAAVGIIAGYFVRKNISEAKIGQAENLAKEII
                     DKAHHDSETVQKEKLLEAKEEIHKWRTEAERENRERRTEVQKYEKRVVQKEEVLDRKL
                     QNLESKEVNLSEKLKVVEKKEEEVEVIKTQQLEKLESISGITSDKAKEIILTNAERDV
                     RREMSIMIKEIESQAKEEADKKSREIIGYAIQKCAADHVAETTVTVVSLPNDEMKGRI
                     IGREGRNIRTLETLTGIDLIIDDTPEAVILSGFDPIRREIARIALEKLIADGRIHPAR
                     IEEMVEKARKEVDNIIKEYGEQAAFETSVHGIHPELIRLLGRLNYRTSYGQNVLKHSI
                     EVAHIAGIMAAEIGADIRLAKRAGLLHDIGKAVDHEMEGTHVEIGMDLLRRYKESKEV
                     IHAMSTHHGDYEPQTVEAVLVTAADAISAARPGARRETLEAYIKRLEKLEEIANSYEG
                     VEKSFAIQAGREIRIMVKPEAINDEEIHLLARDMTKKIEDELEYPGQIKVSIIRETRA
                     IEYAK"
BASE COUNT         8638 a         2138 c         4040 g         6250 t
ORIGIN      
        1 aagctattgg tagtggaagt gggtagacct taacggataa tgccgaagga taagatatag
       61 tctgtgctta catgaaagtg taagaagttc ataagagaac tgcataggta gtagcgagct
      121 tatgtgaacg acaacctcaa aaatgataaa agttaagact tacggttctt aaatatgtta
      181 tttaaaatta aatataaaac cttctaaata attgttttaa ataattacat ttgttaatat
      241 tatgataggt ggttaataaa ttgttcacca cagcattata taatatatta aaatcattaa
      301 aaagtgtatc aaaaaacaat taaagtgagg tgatagcagt gaaaaaagcc tataagttta
      361 gaatgtatcc aaataaaaaa caacaagagt taattaacaa aacttttgga tgttgtagat
      421 ttgtatataa taaatatctt gctaaaagaa tagatgttta taaaagcgat aaagaaactt
      481 ttacttataa acagtgtagt tctgatttga ccaatttaaa aaaagaatta aaatggctta
      541 aggaacctga caaattttca ctacaaaacg ccttaaaaga tttagataat gcatataaaa
      601 aattctttaa agaaaaggca ggatttccta aatttaaatc aaagaaaatt aatagatttt
      661 catataaaac taactttaca aatggaaaca ttatgtattg tggtcaatat ataaaactac
      721 ctaaacttgg tatggttaag ataagggata aacaagtacc tcaaggtaga atacttaatg
      781 ctactatatc taaagaacca agtggtagat attatgtatc attatgctgt actgatgtag
      841 atattgaagt atttgaaaat actaataatc atataggttt agatttagga attaaagaat
      901 tttgtatctc aagttgtgga gactttatag aaaatcctaa gtatcttaag aagtcattaa
      961 acaagcttgc taaattacaa agagaattat cgagaaaaac aatcggtagt ttaaatagaa
     1021 ataaagcaag attaaaagtt gcaggacttc aagaacatat agctaatcaa agaaatgatt
     1081 ttctacaaaa actatctact aaattaataa aagagaatga tattatttgc atagaagatt
     1141 tacaagtaaa gaatatgatt agaaatcgta aactatctcg cttaatttca gatgtatcat
     1201 ggtcagaatt tattcgtcaa ttagaataca aggctaattg gtatggtaga aaaattgtaa
     1261 aggtaggtaa attctttgca agttcacaaa tatgcaataa atgtgggtat aaaaacgagg
     1321 aagttaagga tttaaatata agagaatgga tttgtcctag ttgtaatgaa actcacgata
     1381 gagatataaa tgcaagtata aatatattaa aagaaggatt aagactaata acgattcaaa
     1441 ataaataact tatgtaagaa ccgtaggaac tacggggata gcctgtggag aattagtaag
     1501 acatatttta atatgcaaaa ttctgtgaag caggaaccct gtgactttag tcatgggagg
     1561 ttcagtcaaa ggtatctagt atagttttaa ctcaagacat gatgaataga aataatatta
     1621 gctttaatga tgttgatgga ataacaacat atacaagaga cataaaaggt atagaagttg
     1681 gaattttatt taaagagaaa aaacaaaatg aaattaaagt gagttttagg tcaaaaaatt
     1741 atgttgatgt aagtgaaata gccaagttat ttggtggtgg tggtcatgta agggctgctg
     1801 gatgtactat tagagatagt attgataatg caaagaaaat ggtactagag gcagtgttaa
     1861 aatcaattta aggtgacagt aaaatgaata agattataag tatattgaaa cccacaggta
     1921 tgacatctca tgatgttgta agtagagtga gaaagatttt aaatataaaa aaagttggtc
     1981 atacaggtac tcttgaccca gatgcttcag gtgttttacc aatctgtata gggaaagcta
     2041 caaaagtatg tgaagttatt ttaaacaaag ataaatcgta tatatgtgag cttactttag
     2101 gtataagtac agatacttat gatgcttcag gtgaaatttt aaaaaaagtt gatgatttta
     2161 aatttagtaa tgaagacata gaaagagctt ttgacacaca aagaggagag ataaatcaac
     2221 ttcctccaat ttattcagct ttaaaggtaa atggaaagag aatgtgtgat ttagtaagaa
     2281 gtggtagaca atctgaaatt actttaaaaa caagaagagt aaatataaaa gacataaaaa
     2341 tactaagtat aaaaggtaat aaagtaatgt tttatgttga gtgttctaaa gggacttatg
     2401 tgagaagcat ttgccatgat ataggagaat atctaggttg tggagctcat atgtcgtttt
     2461 tgaatagaac atcttctggt aaatttgact tagataattc aataacatta gaagaattag
     2521 aattatttta tgaaaataaa actttagaca aatacttata tgatatagat tatgtccttg
     2581 attcgtttaa ttatgttgta ttaaacccta atgctataaa atattatagt aatggtggct
     2641 caatagatga taaaaggttt ttaaaaaata atttcgataa agatgatgaa tttgtaagag
     2701 tatacagtac agataatttc ttaggattag gaaaattatc aaaacacaat aatacaataa
     2761 gtgttaaaag tgataagatg ttcatataac caatgtattt aaaaaaacaa caaaagagat
     2821 agtactataa taacttctat agtctatctc ttttacttat gctataatag tttgtgaata
     2881 agttaagagt aaattatatt ttagcgggga acatttatta tggtgattat aaaatctata
     2941 aaagaaatag caaacataaa agaaagtgtc attaccatag gaaattttga tggtgtacac
     3001 aaaggacatc aagttcttat aggaaaaaca gttgaacatg caaaaaaaga aaatatacag
     3061 agtatcgtat ttacatttgc aaatcatcct gtaaattact ttagaccaaa ctcaacaaaa
     3121 aatattataa gcaatgatga taaaataaaa ttattagaag atttgggaat agatatagtt
     3181 gtaatcatac catttgatga gtatatgact aaaatacctg caaaggattt cgtagatgag
     3241 atactagtaa aaaaattaaa agctaaaaag atagtaattg gacatgactt tacatttgca
     3301 agggcaaaag aaggcaatgt taatctatta aaaagcttag aacatgaatt tggttttgag
     3361 gtagaagtaa taaaacccat caaaatcaat gatgtaagag tgagtagtac ttatattaga
     3421 agtttagtat cccagggtga tatggctaat gtcaaggaat atttgggtag aaattacaag
     3481 ttagaaggtt gtgttataca ttctaaacac cttggaagaa ctataggatt cccaacggca
     3541 aatattgacc ttaagaataa tatgctcgtt ccaaagagag gtatttatgc ttctattgta
     3601 catattggag atgagactta ttttggtgct acaaatgtag gctataaccc aacagttaat
     3661 ggaaaaactt tgtctattga aacaaatatt ttagagtttg atagagatat ttatggggaa
     3721 aatataattg ttgaattttt ggaaagaata agagatgaaa gaaagtttaa ttcaatagat
     3781 gacttaaaaa atcaattgta taatgataca aattatgtgt atgaaaacta tgtttgcaaa
     3841 aacaagtaat gtatgataaa atgattaagg aaaataacca ttactcagca tttgaatact
     3901 ccaatcaatg cttagtaata ggcgtttcta aaaaaatacg gaggtaatct aaatgataaa
     3961 caaatcagaa ataataaaag aatatggaag agctgaaggg gatactggtt ctccagaagt
     4021 acaaatagct ttattaacag ctagaataaa cgagttaaat ggacatttaa aaactcataa
     4081 gaaagaccac cattcaagaa gaggactatt aaaaatggtt ggtagaagaa gaaacttatt
     4141 agcttactta aaggaaaaag atcttgaagg atatagagca ttaatagcta aattaggatt
     4201 aagaaagtaa tttcattctt tataaaaaag caggtatagt gtatacctgc ttttttatag
     4261 ttaattcatt ataaagtaaa atagttaata ataaaagtag tttatatgtt ataaaaaatt
     4321 ataaaatgaa taatattggg taagaatatt aaaatagtat acaaatacat aatcaattta
     4381 aaaggaaaga caggataaat atagaaattt tataacagga taattagttg gaataaggag
     4441 gatattattt tgaaaataaa gttagtatgc gatagtttgt gcgatattcc agatgaaata
     4501 tcagaaaaag attatataga gatagttcca cttacagtta tttttaatga tagggaatat
     4561 atagaaggag tagatataaa gaaagaagag ttttataaaa aagtaaaaga aatcaagcaa
     4621 atacctaaaa cttcacaagc tacatatatg gagtttaaag aagtgtttga taagttcata
     4681 acagaaggtt atcatataat ctgtatgaca ggggctgcaa acgcatcagg aacttttcaa
     4741 agtgctatga tagctaaaaa tgatgtaaat gaaaatgaaa aaatacatat atttgatact
     4801 agaaatttat ctctaggtag tggacaatat gttataaagg catgtgaact tcttgaagaa
     4861 ggactgggat ttgaagaaat tatagatgaa ttagaaaata ctcgcagtag tgtaagattg
     4921 ctttttgcac catatacact tgatttttta aagcagagtg gaagagttcc agttgcaact
     4981 gctttgatag gaaatatgtt aaatataaag cctatatttt tctttgataa tggggaagct
     5041 aagttggtaa ataaggttag aggaataaag aatatagcaa gtaaattggt cgatataatt
     5101 ttagaaatga atgaagggtc tttagaagga aaaatcgtca caataggttg tggagataat
     5161 ttacacgatt gtgaaatatt aaaagatgaa gtaaataaaa gaataaaagc aagaagagta
     5221 ttatttactc gaggaggagt ttctatttgc tctcatacag ggccagatat attggctata
     5281 agttgttcta attagtagta atataaggtt tttgcatata tatgtgaaga taattttata
     5341 ttgttaattt atagtatttt tgataatata gtaaatagag tgatatacgt gttttttaat
     5401 aagaggagga caagcattaa tgtttgaaca taaaatattt aaaatggatt ttgcaggaag
     5461 agaactttct gtagaaatag gaaagatttg tgaaatggct agtggtagtt gtatagttcg
     5521 atacagtgat agtatggtaa tggtaaatac aactaaatca gccaaaccta gagacggaat
     5581 agactttttt cctttaagtg tggattatga agaaaaatta tactctgtag gtaagatacc
     5641 tggaggtttt ttaaagagag aaggcaagcc ttcagagaaa gctatactta catcaagatt
     5701 gatagataga ccaataagac ctttattccc aaaaggattt agaaatgatg ttcaggtagt
     5761 tgcaacagtt ctatcagtag accaagattg tacaccagat atagtagcaa tgataggttc
     5821 ttcaatagcc ctttctatat cagacatacc atttaatgga ccaacaggtt cagtatgtgt
     5881 tggccttgta gatggtgcat ttgttgtaaa tccaaacgca gagcaaagag aaaaaagttc
     5941 aatgcatcta gttgtttcag gtacaaagga agcaataatg atggttgaag ccggagctga
     6001 tgaagttcca gacgaggtaa tgcttgatgc tattttattt gctcaccaag aaataaaaaa
     6061 aatagttgag tttatagaag gtatagttgc agaagttgga aaagaaaaaa tgcctgttga
     6121 attataccat gcaggagaag aaataactca attggttcgc gaatttgcaa ctgataagat
     6181 gaaaaaagca gttcagactt ttgaaaagtt agagagaatg gaaaatatgg atagagttaa
     6241 agaagaaact ttagctcact ttgaagaaac tttagaagat tttgaagatt ttgttggaga
     6301 tatagaagaa gtattacaag atataataaa agaagaagta agaaaactta tagtacatga
     6361 aaatgtaaga ccagataata gaaaacttga agaaataaga cctatatggt gtgaaactgg
     6421 catgatacct agagctcatg gttcagccat atttactaga ggacaaactc aagtacttaa
     6481 tgttgctact ttaggtgctt taggagatgt tcaaaaacta gatgggttag atgaagaaga
     6541 aaacaagaga tatatgcatc attataattt ccctgcatat agtgttggag aagctagacc
     6601 atcaagagga ccaggaagaa gagaaatagg acatggtgct ttagcagaaa gagctttatt
     6661 accagtaata ccatctcaag aagaatttcc ttatgctatt agattagttt ctgaagtatt
     6721 aagttcaaat ggttctacat ctcaagcaag tgtatgtggc tcaacattat ctttacttga
     6781 tgcaggtgta cctataaaag atatggttgc aggtatagca atgggactta taaagcatga
     6841 tggtaaggtt gcagtgcttt cagatataca aggtatggaa gaccatttag gcgatatgga
     6901 ctttaaagta gctggaacag agtatggtat aacagcaata caaatggata taaaaattga
     6961 tggtatagat aaagaaattc tacaacgtgc tttaaaacaa gctaaagagg gtagaatcca
     7021 tatactagga gagatgagaa aaactatatc tcagccaaaa ccagaacttt caccatatgc
     7081 acctaagatt gttaaaatgc aaataaatcc tgacaagata aaagatgtaa taggacctgg
     7141 tggaaagata ataactaaga taatagacga aactggagtt aagatagata ttgaacaaac
     7201 tggggaagta tttatatcag gtattgagat tgatatgatt aagaaagctc aagaacttat
     7261 aaataatata gtagttgaac cagaagtagg aaaaacttat aaaggtaagg taagtagaat
     7321 aatgaacttt ggagcatttg ttgagatact tccaggaaaa gaaggattac ttcatatatc
     7381 tcatatagct catgaaagag ttgccaaagt tgaagatgta ttgaatatag gggatgaagt
     7441 tgaagttaaa gttacagaga ttgatgaaaa aggaagagtt aatttatcaa gaaaagttct
     7501 tttaccaaaa ccagaacata aaaataaata acttattata taattaaaag caaagtctta
     7561 ggattttgct tttttaaata caaaaaagta gataatttta aaatgatagt tatggatggc
     7621 ttatagttct ttttctgtca ggctttactc ttataaagaa gctatttaaa agctgattaa
     7681 tagagagctt tattgatata tatagaatca cttaagttat atttagtgca taaacagagc
     7741 ttatttttaa tagtattaaa taagaaacaa tttgtacata attaggggga gttttaatga
     7801 taatgatggt acttaataag agtaagctca aaaaaatcat aatactaatt ttagtagtgt
     7861 tattagtatt atcaggaggg gtaatggtat taaagttatt taacaacaag ccagtattta
     7921 atttatttaa tggtgtagat ttaccatatg aaagaggtac aaaggataaa agtggatatg
     7981 ttgcattaac ctgtaatata gaccttggat gggaaacaga gtacgtagaa tccattttag
     8041 aaacacttaa aaaagaaaat gtaaagatta catttaatgt aactggaaaa tgggcagaaa
     8101 agaataagga tgaattatta aagataaaaa aacaaggaca tgaaataggt aatcatggat
     8161 acaaacattt agattattct acattatcat atgaagacaa ttatgagcaa atagagacct
     8221 ctaaaaagat aattgaagaa attataggtg aaaaaactaa attttttcaa gcaccagcag
     8281 gttcttttgg tccagaaaca gtaaaggctg ctaaagcatt agggtatact tctatcaaat
     8341 gggatgccga tactatagat tggaaataca aagaccaacc agaggtaatc attgatagaa
     8401 tgaagaaaaa agacattaaa gatagtagta taattttaat gcatccaacc aacgcaacga
     8461 caaaatgtat agatgatatt atagctattg taagagaaaa aggactaaaa ccaggaaaac
     8521 ttagtgatgt atttaagtag acaaagtata aatatttggt taagattgta taagttgtag
     8581 ttgaattaat taaaagactg acttataatg taatacatat aaaaaataaa tataattaaa
     8641 acatagtgtt ttcaataatc caatatgaaa caaagaataa attgttagga gaatgtaatg
     8701 tataagacaa aaatactgga aaatgggctt acaataattg gtgaagaaat accatatcta
     8761 aagtcaataa cattaggtat ttggataaat gcaggctcta ggatagaaga agcacaggtg
     8821 agtggaattt ctcattttat agagcatatg atgtttaaag gaaccaaaaa cagaacatca
     8881 aaagagattg ctagttcaat agataatttg ggtggtcaaa taaatgcatt tacaagtaaa
     8941 gaatgtacat gttattatgt aaaactaata gatgagcata tagatacagg aattgatgta
     9001 ttgagtgata tgatactaaa ttctaaattt gataaaaatg atatagataa ggaaagactt
     9061 ataatattgg aagaacttaa gatgtatgaa gactctccag atgacttatc ttatgattta
     9121 ttagtggaaa atatatatgc taatgatgga ttaggaatga atataattgg gacaaaagaa
     9181 tctctgtaca atataactag agaatccatg ttagaatact taaataagta ttatattcca
     9241 aataacgctg ttatttctat agctggaaac tttaactttg atgatatggt ggagaaaatc
     9301 aaatcaaaat ttggacactg ggaaaagaaa aatttaagta tagacataag tgaggctaag
     9361 tttaatcctt gctttatatc aaaaaataaa gatactgaac aggtgaactt agctatgtgc
     9421 ctaaaaggta ttccttttga aaatgatgaa gaagtctatt caatggcagt ggtaaataat
     9481 attttcggtg gaagtataag ctcaaggctt tttcagaaaa taagggaaga aaaaggttta
     9541 gtatattcaa tatactcatc acagacatta tataggaaat gtggtgaatt aggtatattt
     9601 gcaagcatga gtacagaaaa tttacaagat gtatataatt taataaagaa agaaattgaa
     9661 aatataagag aaaactatct tacagaaaaa gaaatatctg aaagcaagga acagttaaaa
     9721 ggaaattata tattggattt agaaagtact agcagtagaa tgatgtctac tggtaaatct
     9781 atgttactta gcaaaaaagt aaaaactaca gatgaaatac ttgaatgtat aaataatgtt
     9841 aatattaatt caataaagaa ggttgttgat aaggtattca atatcgaaaa tattggtaca
     9901 tgtatagttg gaagagatgt agaaaagatt ctacacttgg attaatattg aaaaaagtaa
     9961 atctctggag gtataaaata tgaatttatc tgaaatagca ggtaaggaaa tagttaactt
    10021 ggtcacagga gaaagattgg gggtcattgg agaatgtgac cttatactag atgaaactac
    10081 aggcgatata ttagcgcttc taattccaaa agaaaaagga ttttttgcca gaagaaaaga
    10141 taagtcattt ttagaagtac catggagaaa tgtaaaaaaa ataggtaatg acatgataat
    10201 tatagaatat gagggatata tttaggagga aaaaatgagt attttagtgc aaaagtttgg
    10261 tgggacatca gtagaatcat atgaaaaaat gaatgaagta tgtaagatag taaaagcata
    10321 caaaaaaaat gatgaagaat tacaattagt attagtagtt tcagcaatgg gaagaaaagg
    10381 agctccatat gctacagata cacttataaa tttgtgtagt gcagtaaatg atgagccaag
    10441 taaaagagaa cttgatttaa taatgtcttg tggagaaata atatcaggaa caattcttgc
    10501 taatttattg aatgcacagg ggatagattc tgttttcttt actggtcagc aagcaggtat
    10561 aattacaagt gatgaatatt ctaatgcaaa gataaagtat ataaatccta aaaaggtaaa
    10621 aagagcttta gatgatggta aggttgtagt tatagctggg ttccagggtg taacagatga
    10681 tggagaaata actactcttg gaagaggcgg aagcgataca tcagcagttg ctattggtaa
    10741 agctttagaa tgtgaaacag ttgaaattta cactgatgtg gatggtataa tgactgcaga
    10801 ccctagagta gaaccaaacg ctaaagtatt gagttttata gactatgagg aagtattcca
    10861 aatggctgac aaaggtgcaa aagtaataca tccaagagca gtacagttgg ctaaaagtgg
    10921 aaatataact ttagccataa agaatacaat gaatccaact tttgaaggta caaaaatagg
    10981 ttctttatgt agacacttag aagacaatat agaatatgaa caagaaagag attttaaggt
    11041 tgctgttgca aataaagata gcgtagcaca agttaagatt aagtcagcag aagaagtgtt
    11101 tacagaagta ttaaatgaga tagaaaagaa acttataact atagatatga taaatttctt
    11161 tatatcagaa aaagcatttg ttgtagaaga tgctgatata aaatcattaa aggaaatact
    11221 agataaattt gaattagatt atgaagtaaa tagagactgt gctaaggtaa cattgatatg
    11281 ttcaagaatt gctgatgaaa tgtctggtat catgtcaaag gtagttagag gattatcaaa
    11341 agcaggggta tctcttttac aaacatcaga ctcaaatatg actatatctt gtttagttag
    11401 tgaagaagat atgcatacag cagtacatgc tatacaccaa caattttatt taaaataaac
    11461 tgtataatac aattattttt taatcaaatt taagaatttc atatatatct taatatattt
    11521 gatttatttg gtaaaactaa attaaatata attttgatag gagttttttt atgaaagatt
    11581 atagagaaga taatgaaaaa tttgataaag ataattgtag tgaagaatct agttgcgaag
    11641 agagagaatg tataaagcaa tttggtacca atgaaatgcc acctcaacct cctaaagata
    11701 ttcaatgtat aactataatt ggagaaattg agggacattt tataggaaat cctcaaaaaa
    11761 aagctacaaa gtacgagcat ataattccaa tgctatactc aattgaggaa agtaatgatg
    11821 ttaaaggagt gttagttgtt ttaaacactg ttggaggaga tattgaagca ggtttagcta
    11881 ttgcagaact tttaaacagt acatctaaaa aagtagttac tcttgttcta ggaggaagtc
    11941 atagtatagg tgttcctctt gctacagcag gagattactc atttatagca ccaacagcaa
    12001 ccatgattat acatccagtg cgaactactg gtcttgtgat tggtataaat gagacttttg
    12061 aatattttaa aaagatgcaa gatagaataa ttcaatttat aataagaaca tcaaatatca
    12121 aaaaagatgt acttgaaaaa cttatgcatg aaaaagatga acttgtaagt gatgttggta
    12181 gtgtattaat aggaaaagaa gctgtggatt atggtcttat agatgaagtt ggaggactaa
    12241 aagaagcact taaaaaatta agagagctta taaaagaatc tgaggaagaa aaaaataatg
    12301 attaaaattt gtttaaataa taaaatttat gatataatga tgtaataaag taggagtgtt
    12361 agtgttaagg cattagcact ttttgctgtg aaggggtaaa acttgctaaa aataaggagt
    12421 gatattaatg gccacgaaaa agaagaaaaa aaagaaggta aataccttaa gttttaatgc
    12481 agaatatcat aatttaataa caatatttat aggtgtattt ttattatata gtttaaattc
    12541 taattctatg ggatggatac ctgtgttaat gcaaaatctt tttaagggac tatttggagg
    12601 gctttcaata gcaataccat ttatagtaat tataacagga cttttaggat tttttgatgg
    12661 aaatgaatat atatataggc taagaaagac taaactatac tacataatta ttttatttat
    12721 atttgtattt tatggattat taaatgcagg aactcttcct gtagatagcc cactaaaagg
    12781 taacatgttt gatgatgtta tgaaattggg tgtaagtgga caaggtagtg gtttgatagc
    12841 aacaactatt gcgtattata tgagtaaaat atttggtata gcaggtggat ggttaataag
    12901 tatcttcgca cttatacttt ctgtaatgtt tatatttaat atttctataa aagatttggt
    12961 gtcaaatgca aaatcaaaat ctaaagcatc taaagacagc aatttaacgt ttaaagataa
    13021 aattgcaaat atgaaaaaat ctgcaataga tatgatgact gatgaagtag atgatactac
    13081 tataaataaa aaaccaggtt tctttaaagg gttaatgtca aaaggtctta ataatgatga
    13141 tgaagaagat gaatattttg aagaagaaaa tagtgatggt gtagatgata aaactataaa
    13201 aatagttgga tttaataagg cagaagatga gtatttagaa atattagaag gaactcaaag
    13261 tatgccagag ttagatgttt taaaagaatt acaaaaagct accaatgaaa atccagttgt
    13321 agatactaaa ccagaaaaaa aagttgatat agctaaacct aatttaaata tagaaaaaac
    13381 tcaacctatg agtattgtag cagagccagt taatgaggat tattcaaact ataaaaagcc
    13441 tagcattgag cttttaaata aagtaaataa gaagtctgat gaaaatggta aaaagaaagt
    13501 gttgaaaaat gcttctcttt tagaaaagac actatcagat tttggagtgg aagcaaaaat
    13561 taatcaagtt acagttggac ctactataac aagatatgaa atacaaccaa gtccaggagt
    13621 caaggtaagt aaaattgtaa atttaactga tgatatagct ttaagtttag cagctaaaag
    13681 tataagaatt gaagccccaa ttcctggtaa aagtgcaatt ggaatagaag ttccaaatga
    13741 agaagctcaa atggttggtg tgagagaagt tctagaaagt gaagaattta ataattttaa
    13801 ctctcctctt gcaatgggac ttggaaaaga cgtagcagga aaaattataa ttggagatat
    13861 aggtaagatg ccacacttac taatagctgg ttctacaggt tcaggaaaga gtgtgtgtgt
    13921 aaatacatta ataagtagta ttttatataa ggcaaatcct gatgaagtaa aattactatt
    13981 aatagaccca aaagtagttg aacttgcaaa ttataatgga ataccacatc tattgatacc
    14041 agtagttact gaccctaaaa aagctgcaaa tgctttaaat tgggcagtta cagagatgaa
    14101 tagaaggtac aaattatttg cagatgctca agtaaaagat gtaacaagtt ataatgagaa
    14161 agcggaagaa aaacttccta aaatagtaat aataatagat gagttagcag atttaatgat
    14221 ggcaagtgca aatgatgtag aagattatat ttgtagatta gctcaaatgg caagagctgc
    14281 tggaatgcac ttgattgtag caactcaaag accatctgtt gacgttataa caggggtaat
    14341 aaaggctaat ataccatcta gaatagcatt tgcagtatca tctcaaactg attcaagaac
    14401 aatccttgat atgggtggtg cagagaagct tctaggtaaa ggtgatatgt tattctatcc
    14461 acttggtgca gcaaaaccag ttagacttca aggggcattc atatcagaga gtgagtcgga
    14521 aaaagtaatc gattttgtaa aaagtcaggt taaagatgga ataaaatatg aagaagatat
    14581 aattgaaact atatctaagg ttaatacttc aaagggtagt gatgaggatg agtttttgag
    14641 tgaagcgata gaatttgtcg tggaaagtgg tcaagcatct gcctctatgc tacagagaag
    14701 atttaaaata ggattcaata gagcagctag acttatagat tctatggaag aaagaggaat
    14761 aattggagca agtgagggaa gtaaaccgag aaaggtatta ataagcaaac aggatttgca
    14821 gaatttagaa ggtgaataga attgtcagtt ataaaaatag aaaaagcact taagctagat
    14881 aaagtaatat ttgtagatgt gagaactgaa ggagaatatg aagaagacca tatattgaat
    14941 gcaatcaata tgcctctttt taaaaataat gaacataatg aagttggaac aatttataag
    15001 atgcagggaa aacatgaagc aatacaaaaa ggatttgact atgtatcgta taaattaaag
    15061 gatatatatt tacaagcagc agaacttgca ttaaattatg ataatattgt catatattgt
    15121 gcaagaggcg gaatgagaag tggcagtata gtaaatttat tatcatcatt aggtgtaaat
    15181 gtatatcaac ttgaaggtgg atataaggct tatagaaatt ttgttttaga gtatttaagg
    15241 catgtaatgg atacaaaaaa ctttgtatct gttcatggat tgactggtac aggaaagact
    15301 gatttgttac atttattaga tgaaaaagga atagacgtgc tggatttaga aggcatagct
    15361 aaaaacagtg gttctacctt tggttttata acttttgata aaaagccacc atctcaaaag
    15421 aactttgaaa caaaactatt tgaaagtata tttttttcga aagagaatta tatatttgtc
    15481 gagagtgaaa gcaaacgagt tggaagtgtt acagttccaa atgaaatttt cgaggcaatg
    15541 acacgagaag gacatcatat attattagaa tgtgatattg aaaatagagt tgatagactt
    15601 tgtagagatt atatttatga taaagatgaa ggtaatatat tgattttaaa agaatgtata
    15661 aacaagttta gaaaaagatt gggtaataaa gtagtagatg attatattga tttattagaa
    15721 tcaggtgaat ataaagaact tgtaaaaaga tatcttttag aatactacga cccactttat
    15781 atgcattcag tagagaaata taagtatagt aagattataa attttaatga tacacaaaaa
    15841 gctttagaag atgttataga cttatatgag agtatattgg aaggagaaag tgaatgttaa
    15901 aaatagcatt ggaatcatta ggatgctcaa aaaatttagt agatgcagaa ataatgatgg
    15961 gaattttaaa taacaaaggc tataaattaa ttggagattt tgaagaagct gatgtaatta
    16021 tagtaaatac atgtgggttt atagagtcag ctaaacaaga atctatagat acgataataa
    16081 actttgcaga gttaaaaaaa actggcaatt tgaagttgtt gatagtaaca gggtgtctag
    16141 cccaaagata ttctgaagaa ttaaaaactg aaattcctga aatagatgct atagtaggaa
    16201 caggaagcta tcaaaatata gataaaatac ttaaagaatt aagtgaaatg catcaaattg
    16261 taagccttaa tgatatagag tttgtattta atgaagattt accaagatat atatctacac
    16321 ctagctatat ggcctattta aaaattggag aaggatgttc caataattgt acttattgta
    16381 taataccaaa actaagaggt aaatatagaa gtagaaaatt tgaagatata attaaagaag
    16441 ctaagaaatt agctgaatct ggagtaaaag aacttgtggt tatagcacag gatacgacaa
    16501 agtatggttt tgatttatat ggaaaagaaa gattatcaga acttttagaa gaacttgcaa
    16561 aaatagatgg atttaagtgg ataagggtta tgtattcata tccagaatct ataacagaag
    16621 aattgataca agttataaag aaatatgata atatatgtag ttactttgat atgccaatac
    16681 agcatgcaag taacaatatt ttaaaattaa tgaatagaaa aactactaaa gaagatatat
    16741 taaataaaat caatctgata agaagtaata taccagatgc tatacttaga actacaataa
    16801 tagtagggtt tcctggtgaa acagaagatg acttcaaaca acttgtggac tttgttgaag
    16861 aggttaaatt tgatagactt ggtgcatttg catattcaag agaagaagat acaccagcag
    16921 atagattgcc aaaccatata gatgaagaag taaaaataca aagaagagat actttaatga
    16981 tgattcaaca aaaaatatct gaagaactta atgacaaaaa gataggaaaa acttatgagg
    17041 tgttaataga agaacagata gaagataatg tatatacagg aagaacacaa ggtgatgcag
    17101 aagaaattga cagtatagtg tatgtaaaaa gtgtagacaa tcttgaagta ggagaatttg
    17161 taagtgttca aataaatgat gcaatggaat acgatttaat gggagatgtt ttatatgaac
    17221 ttgcctaaca agttaacttt gtttagaata tttttaatac cagtatttgt tttaattatg
    17281 ttgctcaatg taccaaataa atttttaata gcttgtatta tttttataat agcttcaatt
    17341 actgatgctt tagatggaaa aatagctaga aaatacaatc tagtcactga ctttggaaaa
    17401 tttatggacc cattagcaga taagttattg gttatttcag cacttacatg tatgatagaa
    17461 gaccatcttg taagtagttg gatggtaatt ataatagtgg ctagagagct tacagttagc
    17521 atattaagag ctatagctgc tgctgatgga aaagtaattg ctgctggaaa cagtggaaaa
    17581 cttaaaacga taactcaaat ggtatctata gtgtttttat tgttaggtgc tcagtttgaa
    17641 aatgtattga tattaaatat tggtgaaatt ctcattctta tagctacact acttacatta
    17701 tattctggat gggaatatct atataaaaat aaagagcttt ttatgtcttc taagtaaaaa
    17761 attatgcttt aataaataaa aactaatgat taataaataa aaaataacaa cttaaaattt
    17821 taaaaatgta aaaaagggta tactattata gtatacctct tttcatttta agaatatttt
    17881 cttttgtgta tataattatt aataatggtt tataaataaa atgtaatgaa taaaaatata
    17941 atcattagta gcgtttttaa attgactagg tttgatttat gttatataat taatatataa
    18001 caagagaaca aatgtttgta gataaatgaa gggatggtat agagatgagt gtagatcaag
    18061 aaaaattaaa agcgttgaat gaagctttag gtaaaattga aaaagatttt ggtaaaggtt
    18121 cagtaatgaa attgggagaa gcaacatcta tgtctataga tgttatatca acaggagcga
    18181 ttggtttaga catagctatt ggtataggag gtctacctag agggagaata gttgaagtat
    18241 atggtccaga atcttctggt aaaactactg ttgcgcttag ttgtgtagca tcagctcaaa
    18301 aagatggagg aatagctgca tttatagatg cagaacatgc acttgaccca gtatatgcaa
    18361 aagctttggg tgtggatgtt gataacctaa taatatctca accagataca ggtgaacagg
    18421 ctttagagat agcagaggca ttgataagaa gtggagcgat agatataata gtaatagact
    18481 cagtagcagc attagttcca aaggctgaaa tagatggaga tatgggtgat tctcatgtag
    18541 gtttacaagc tagacttatg tcacaagcac ttagaaagtt aactggttca attaaaaaat
    18601 caaattgtgt tgctatattt ataaaccagt taagagagaa agtaggaata atgtttggaa
    18661 acccggaaac tactactgga ggacgtgcac taaaattcta ttcatcagtt agattggatg
    18721 ttagaaaaat agatacaata aaacaaggtg ataaagttat aggtagtaga actagagtta
    18781 aagttgttaa aaacaaagta gcaccaccat ttaagcaagc tgaatttgat ataatgtatg
    18841 gagaaggaat ttcaaaaatt ggagaccttt tagatatagc tgctgatgta gatatagtta
    18901 aaaaatcagg ttcatggtat agttacaatg atactaaact tggacaagga agagaaaatg
    18961 ttaaaaaatt cttggaagat aatttagatt taactactga aatagatgag aaagttagag
    19021 cattttacaa tttaaatgaa gaacatgaag aatcaggtat ttcagtatca aaagaaattg
    19081 tagaagaata agtaaaaata caaaaaaata actagtaatt aaagacatgc cacgctccct
    19141 attagcttga cacaatgttg aaaaaattat aaaattaagt gaggataaaa tatctaaatt
    19201 taattttaat tattaggaat attttttaat catagtgatg acattttggg attattaacg
    19261 aaggaggtgg atgtcataga tagtgtagta atgattgtaa taggtgcagc tgttggtatt
    19321 atagctggat attttgttag aaaaaatata tctgaagcaa aaattggaca agctgaaaac
    19381 ttggccaaag aaataataga taaagcacac cacgactcag aaacagtaca aaaagaaaaa
    19441 ttactagaag ctaaagaaga gatccataag tggagaacag aagctgaaag agaaaacaga
    19501 gaaagaagaa cagaagtaca aaagtatgaa aaaagagtag tacaaaaaga agaagtctta
    19561 gatagaaaat tacaaaattt agaatctaaa gaagtaaacc taagtgaaaa attaaaggta
    19621 gtggaaaaga aagaagaaga agttgaagta ataaaaactc aacagttaga aaaattagaa
    19681 agtatatcag gaattacttc tgataaggcc aaagaaatca tcttaaccaa tgcggagaga
    19741 gatgtaagac gtgaaatgtc tataatgata aaagagatag aaagtcaagc taaagaagaa
    19801 gctgataaga aatcaagaga aattatagga tatgcaattc aaaaatgtgc agcagatcac
    19861 gtagccgaaa ctactgtaac agtagtaagc ttgcctaatg atgaaatgaa aggtagaata
    19921 ataggtaggg aaggtagaaa tataaggact ttagaaacct taacaggtat agaccttata
    19981 atagatgaca ctccagaagc cgtaatttta tcaggatttg atccaataag aagagaaatt
    20041 gcaagaattg ctctagaaaa attaatagca gatggaagaa tacatccagc tagaattgaa
    20101 gaaatggttg aaaaggcgag aaaagaagtt gacaatatta taaaagaata tggtgaacaa
    20161 gctgcatttg aaactagtgt acatgggatt catccggaat taataagatt attaggtaga
    20221 cttaactata gaactagtta tggacaaaat gtacttaaac attctataga agttgctcat
    20281 atagctggta taatggctgc tgaaatagga gcagatatta gattggctaa gagggcaggt
    20341 ttattacatg atataggtaa ggctgtagac catgaaatgg aaggtacaca tgttgaaata
    20401 ggtatggatt tacttagacg ttataaagag tctaaagaag ttatacatgc catgagtact
    20461 catcatggag attacgagcc tcaaacagta gaggctgtat tagttacagc agcagatgca
    20521 atatcagctg ctagacctgg tgcgagaaga gaaactttag aagcatatat aaagagactt
    20581 gaaaaattag aagaaatagc taattcatat gaaggtgtag aaaaatcatt tgctatacaa
    20641 gctggtagag aaataagaat aatggtaaaa ccagaagcta taaatgatga agaaatacat
    20701 ctattggcta gagatatgac taagaaaata gaggatgaac ttgaatatcc tggacaaata
    20761 aaagtaagca taataagaga aacaagagct atagagtatg cgaagtaaaa gaaataatat
    20821 ctaaataata agaaaatatt tttagaaatt taaatttgcc acaagatatg ataatatatc
    20881 ttgtggcttt taaattgttt aagtttaatt ttatataatg caaaaataat ctaagtgcta
    20941 aaagtgctac ttacaaaaga ttaataaaat aaagctttat atatgtatta tttatataat
    21001 tatccaagtt tgtttgatat aatgaagttg taaaatcaat actttactac aaaataaata
    21061 gtaaat
//
LOCUS       DAJMZY010000075        20019 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.075, whole genome shotgun sequence.
ACCESSION   DAJMZY010000075 DAJMZY010000000
VERSION     DAJMZY010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 20019)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20019)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20019
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.075"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            345..1775
                     /locus_tag="OE968_002585"
     CDS             345..1775
                     /locus_tag="OE968_002585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCP7219859.1"
                     /translation="MSSQESKPKGNLISNFRDDMRDPKKRAIYTYSSSINLAYNFIGY
                     FVSTVTNIFLTDVAKLGVIMAGGMQIIQSFIKIAVAPITGTVFDKQPFKKGKYYPWLR
                     YAPAALALTYGIFFIVPLMKISPALLLPLMTALLLIASCAQQVVFTIIYAIYPVVAKT
                     PRDRVIGSTTTNIFKEVGKFLVGFSYPLLLVLFADVLGGEGMGYLGTYLFFAAGCLLV
                     FWFSSTEIIKSGAEEEVLQKEEKPKIKASEMAKALFTNVPLMMAFCLEFLICIRSIGL
                     GPLAPYYFKYVIEDERGLAVFLSIMPLVSVAFMFFAPVFIKICREQKLASIISFSICA
                     LCHLLVAWTPWGKTTLGVTMLLAIGGGFSNVVSIINLNFFAGSCDYGHWKSGKDLPGL
                     SMSLYPVAIQVGVLLATTIRTVLMNSMGYQADMVVTEAVKSGFINMISYSMAIPLIIA
                     VVIAILYPVSDKKLNQIREELNQRNA"
     gene            1878..2981
                     /locus_tag="OE968_002586"
     CDS             1878..2981
                     /locus_tag="OE968_002586"
                     /EC_number="2.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate transaminase"
                     /protein_id="HCP7219860.1"
                     /translation="MIEKLLRNTVKELHQYVPGEPIEKVKEKYGVKEIIKLASNENPL
                     GPSPKAIEAMIEMLKQGQLYPEPEANELRRKLAEKLDLKPENFIVANGADNVITLIGE
                     AFINRGDEVIYCNPTFPSYRTATIKNEGIPVEVPLTEDYKYDLQGILDKITDKTKLIC
                     VCNPNNPTGTIVDDKELEEFLKKVPENIITILDEAYIEFLTVPNYVDGLKYVRENYNV
                     IVTRTFSKIYGLAGLRVGYGIAKDEIIRTLFTVKEPFSANRVAISGATAALDDEEFIK
                     ETYELNRVGMAYFKEEFTKMGFDVVDSQSNFLYVDMKTDIPKLFEDLKKRGFVIRPSA
                     THARVSIGTMEENKKFVAVLKEILNIKGEPSIG"
     gene            2996..3232
                     /locus_tag="OE968_002587"
     CDS             2996..3232
                     /locus_tag="OE968_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HCP7219861.1"
                     /translation="MKRGVDMNLKINAERCKSCEYCVISCKKGALKISSKINKEGYAH
                     VEVDESKCILCGICYQVCPDNVFEIIKEEACQEA"
     gene            3249..4298
                     /gene="vorB"
                     /locus_tag="OE968_002588"
     CDS             3249..4298
                     /gene="vorB"
                     /locus_tag="OE968_002588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate dehydrogenase subunit
                     VorB"
                     /protein_id="HCP7219862.1"
                     /translation="MKKMWKGNHAIAEAALRGGCEFYAGYPITPQTEVIEFLSHRMSE
                     LGRTFIQSENEMAAIYMVYGAYASGMRSMTSSSGPGISLKQEGISYLCANHYPCVIVN
                     VQRWGPGLGSLDSAQTDYLRDTRGGGNGDYHLIVYAPNSIQETVDLMYNSFDVAEKYR
                     VPVEILTEAALGQMMEPVEFPEFKKREGDLGWTYDGSNRDHAKVADNQKPTFCMEKRM
                     RITENEQQWEDYQVEDAEYVFVAFGIPSRTTMNAVRRLREQGEKVGIIRPITVWPFPY
                     KAFEKVSKDVKGFISVESTDTGQLVEDVALTSKKVCKENVPVYGLFSGNHIPKTLQVM
                     DTYSKIKSGEIKEVF"
     gene            4300..5040
                     /locus_tag="OE968_002589"
     CDS             4300..5040
                     /locus_tag="OE968_002589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate oxidoreductase"
                     /protein_id="HCP7219863.1"
                     /translation="MATEKLTPSVVSIPNKFCPGCGHGIVNRIIAEVIEEHGYEKNHV
                     LTLGVGCVCNMNFSWNGDKMQTAHGRASSTAIGVKVALPDTLVMTYQGDGDAYVIGLS
                     ETLNTAYRNHNVTVFVINNNNFAMTGGQMSWTTMPGQVTTTSVNGRDIKTTGSPLKVP
                     EMVANFFDVAYVARGSVHSPKEIINLKKYIKNAIEAQLNGEGYSLVEILAPCPTNWGV
                     SLEKSIKWMEEEIVPYYALGEFKQRDGE"
     gene            5043..5582
                     /locus_tag="OE968_002590"
     CDS             5043..5582
                     /locus_tag="OE968_002590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoacid:acceptor oxidoreductase family
                     protein"
                     /protein_id="HCP7219864.1"
                     /translation="MEKELVFAGFGGQGVLTLGLIVAESALELGKQVTWMPAYGPTMR
                     GGKAYSVVKFSDESIGGPDMEEIDVLVAMNKPSLDYINLVKEGGTVVINTSAIDENVT
                     LREDISVVKINCQELAQKVNNPKAANIVVLGALIAKTGLFEKELALKTMCDFFEEKGK
                     GKFNVQNEAAFMEGYNNAI"
     gene            5706..7805
                     /locus_tag="OE968_002591"
     CDS             5706..7805
                     /locus_tag="OE968_002591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate--CoA ligase family protein"
                     /protein_id="HCP7219865.1"
                     /translation="MSLEKLIRPKSIAIVGVTDKLGFGRSAALSIVKSKETDRVYYVN
                     PKREELFGRKCYKTIQEVPEVVDCVVVCTPRNVVPSVLKDSGELGTKAAVVYASGFAE
                     EGTEEGTDLENQLIEISNTYDMKILGPNCMGLLNCIDKVNLWAGGSKWDLDTKKPGIG
                     IVGQSGFITAEIVSSDYFNISYGFSTGNGNIVTLEDAVDFLVDDDYASVIAIYLEGLK
                     NPQKFIDALKRAAQKRKPVIILKSGRSEKGAISAASHTGNLAGSSKAFESIFEKYGVI
                     SVENLEQFMCLAQAFSVLDGNLPANSNFAAINFSGGENTICADLAEENGVELAEISSE
                     TKEEMKKYLPGFATPKNPLDATTALFHEKDMIVGLLHTFEKDDSVGFTMVGANIRDEE
                     NEMHETLCKAVSEAREQGLKKPVFAVPTLEGNRYLDYRTRLEDNQVPIMSSVGTTFTC
                     FNKMAKFIDYDYSKRTLEFKAVKKRESNNVVALSELDSKIEMKKYGVPVPGQGNAKSI
                     DELDEILKYIKYPVVLKINSSEILHKSDVGGVKIGIENRDEAVDAYNEILTNVKKAKP
                     DANIDGILVQEMVESGIEIIIGITNDDQFGPMLLVGLGGVFVEVFKDTTLYPLPINHD
                     EAIMMLKKLKSFKLLNGYRGSEPCDIDALADMMVKLGKYAYENKDEVKEIDLNPVFVY
                     PKGKGVCAVDALIVKYK"
     gene            complement(8072..8587)
                     /locus_tag="OE968_002592"
     CDS             complement(8072..8587)
                     /locus_tag="OE968_002592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferritin"
                     /protein_id="HCP7219866.1"
                     /translation="MISAKMEKLLNEQINHELYSAYLYLSMSSYLEAEGLKGFSNWFY
                     VQYKEETDHAMFFYKYLHNVGGKVQLDAIPMPDSDFTSAMDILERTLAHEKKVTALIN
                     NLAAVANSESDFRTSQFLLWFISEQAEEETNCEDNIKRVKLAGEGGLFFVDQEFANRT
                     YAAPTNPPVTI"
     gene            complement(8679..9890)
                     /locus_tag="OE968_002593"
     CDS             complement(8679..9890)
                     /locus_tag="OE968_002593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HCP7219867.1"
                     /translation="MSNKQGSNIKDVKIKNKLIILKLLSTNTPMSRVDLAKSTGLTKM
                     TLSNLVTELINENMIREIESSTLNAHSSGRKPILLDISNISPCICGILIRRNICKVII
                     SDLKGNIVKQLSETYPKCLSNDVLKDIIKRMFTKIMKINKRDIIGIGISSIGPVDDIN
                     GTILNPPDFGNVSNLNIVDFIKEMSDLPIFLINDANSGALAEKMYGLGKNISNYIYLH
                     IMNGIGAGLVLENKLHTGNLGQSGEIGHTSINFSGPLCSCGNNGCLDYYTSVSNLIKR
                     IESLSHIYPNSPLINCKDFSLVKLIDEANNKDSLAMFLLDEFCTYVSYALVNTLTLID
                     CSSIIIGYDFNIPGTFIENTLLKKLTASASFSKYKKISVRHSNFGANAPLIGSIAIVS
                     YNFFNGSINFY"
     gene            10566..12008
                     /locus_tag="OE968_002594"
     CDS             10566..12008
                     /locus_tag="OE968_002594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HCP7219868.1"
                     /translation="MRTIRRVLALGLTLAIFLINVPNVDALTSDTIKGNNIYETAGLI
                     ADKKSYDTAIMVNMDNSIADGLSASGLAGAVDAPILLAQKNKIPNETKQRLKNVKKIY
                     IIGKELSISKSVETELKNTGAQVTRLGGDDRIKTSYSVAKEVNGIKKVDEVILTNAYK
                     GEADTISAAPVSVRDIAPIVLTDGKSVPFSTSNVKTYAVGGSISMSTSLVNKTNAKRL
                     GGSDRYDTNKKVIKEFYPDASEFYLSDGYDLVNALTGSTIAKENPIVLVSESSDKSIL
                     AGADKITRLGSISDSVYNKCVSAAQNNGDSSTKGESPMKNETSILGQPTASLEACLKW
                     AKSKKANDLFIELIPILYDTAVQEGVNPVLAVAQSAKETGFCNFGGVLDASFKNPCGL
                     KTSVGGSDTDKNAHSRFDTWEEGILAQIQHLCLYAGQDGYPLSNPVDPRHEKSLFGKA
                     KTVESLSNNWAGGQYGQDLVRMMGEIEATK"
     gene            12050..12403
                     /locus_tag="OE968_002595"
     CDS             12050..12403
                     /locus_tag="OE968_002595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219869.1"
                     /translation="MKKSNIFSIIFPTVIMVLMFLTFATDIFNIPDIQSKSIFVVGMV
                     LIFPISFLIQGIICVLNKTNWILSLIVSLVTYIVLMYIFLNDSAYIYVLLYTAFYMIG
                     HITAKLYYKIKTFKN"
     gene            12594..13415
                     /locus_tag="OE968_002596"
     CDS             12594..13415
                     /locus_tag="OE968_002596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphatase HisJ family protein"
                     /protein_id="HCP7219870.1"
                     /translation="MNLIDNHIHTNFSSDGKDSMEDTIKKAISIGVRYLTFTDHLEHD
                     EDRGFCINYNDYVPVFNKFKEKYKKDIELLLGVEVGYRKHLKNEIEEIINSNPFDFVL
                     CSTHTIDNVPVPSKEYFKGLSKEDAYYKYFNSILETNREFGDYNIYGHLDYISRYGIY
                     SDNRVIYNDFKDVIDEVLKSIINNGSGIELNTSGYRYGLNAIHPNEDILKRYKELGGF
                     IVTVGSDSHRVEDICKDFDVAYDMLKYLDFKYVSLFKERETYFVNIEKVKSNNIA"
     gene            13673..15556
                     /locus_tag="OE968_002597"
     CDS             13673..15556
                     /locus_tag="OE968_002597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HCP7219871.1"
                     /translation="MSNKNKENITLSNQIKGTIQNSLTKEAILHIPMSNYAYGYDRET
                     LHIRLRTKKNEAKRVILRIGDQYVWDKGGAGGGNLNASGVGWSGGTNIVMSKEVETEL
                     FDYWIAKCKPLNKRSRYGFIIEGQEEKLLFTEKRIIELGNENDEKELCEIGNFFGYPY
                     LNYIDIPKVPNWVKDTVWYQIFPDRFANGDPSINPEGVDKWGAIPTRDNFTGGDLQGV
                     IEHLDYLSDLGINGIYFCPITIGKTNHRYDTVDYMEVDPTLGDKETLKKLIEEAHKRN
                     IKIMLDAVFNHIGYYSKQWQDVVQNKENSRYKNWFYIKDMSKIDTPIEQIDEKNIPYE
                     TFGCEKYMPKLNTENSEVIKYLLDVGKYWIQEFDIDAWRLDVSNEVDHVFWRKFREEV
                     KKVKPDIYILGEIWHGSLPWLMGDQFDSVMNYLMSEAMKKFFCTDEINAEEFKYMIND
                     VMVSYPIQVSEVIFNLLGSHDTTRILTYANGNIDRFKLAYMFMFVQTGCPCIYYGDEI
                     GMEGELSSISEGQRKCMEWNEEKWNKDIFDFMKKIIRLRKENKELRSISNEWVLADKE
                     NGTIILKKESISIIINNSSKNIILTLPDYLANKKVKDLYEEEIVDLKEELMLEKYKFI
                     ILK"
     gene            15781..16461
                     /gene="pgmB"
                     /locus_tag="OE968_002598"
     CDS             15781..16461
                     /gene="pgmB"
                     /locus_tag="OE968_002598"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HCP7219872.1"
                     /translation="MIEAFIFDLDGVITDTAYYHYMAWRKLAHKVGIDIDTKFNESLK
                     GISRMESLDRILEFGNKKYSFSEEEKVRMAEEKNNYYVSLIDEITSNDILPGIESLLI
                     DVKSNNIKIGLSSASKNAINVLNHLGISDKFDFIADAGKCKNNKPHPEIFLMSAKGLN
                     VNPQNCIGIEDASAGIDAINSANMFSVGVGNYENLKKANLVVDSTNQLKFEYIQEKYN
                     EYIVRRII"
     gene            16458..18743
                     /locus_tag="OE968_002599"
     CDS             16458..18743
                     /locus_tag="OE968_002599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HCP7219873.1"
                     /translation="MKCLFSNVDEWKIIQDKIEIKENRLAESIMSIGNGYMGMRGNYE
                     ENYSGDTHKGSYIAGVWFPDKTRVGWWKNGYPEYFGKIPNSVNYIGVRIFIDDVELDL
                     AKCKVEDFYRELDMKNGILNRRFIVNINDKKFEVRVARFLSISVKELAVIKYSIKSLN
                     SNTKIKFVPYLDSNIKNEDSNYEEKFWNGISSSSLEYKGSILSRTKENAFNTPVFTVG
                     SMMYIKTNGDVEAVSHESDYNYCENSITMDVLKNEVASIEKYVSITSTRDYKESELLR
                     KCEDILNRELSKSYDDILNEHTKLWNKRWESADVKINGDKSSQQGIRYNLFQLFSTYY
                     GEDSRLNIGPKGFTGEKYGGATYWDTEAFCVPVYLGVADKEVTRNLLEYRYNQLEQAK
                     DNAKKLGLKGALYPMVTFDGVECHNEWEITFEEIHRNGSIVYAIYNYTNYTGDYKYIK
                     EKGIDVIIEIARFWASRVHLSTKKDLYMIHGVTGPNEYENNINNNWYTNYIAKWCLDY
                     AVENILRLEKECNECIDRNNVTREEVEFWKIISNKMYLPYDEELQIIIQNDNFLDKEF
                     VEVKDLPKENFPLNQNWSWDKILRSCFIKQADVLQGIYYFGNRFTKEEKKRNFDFYEK
                     YTVHESSLSSSIYSIIASEIDNLEKAYELYSRTARLDLDNYNNDTNDGLHITSMSGSW
                     LSIVHGFAGMRTWNETLSFDPKLPKEWKNYSFNINYRDNIINVDVCSDLIKIENLKGR
                     PIKIIVYGKKYILEKCIKIDK"
     gene            18968..19861
                     /locus_tag="OE968_002600"
     CDS             18968..19861
                     /locus_tag="OE968_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HCP7219874.1"
                     /translation="MKNKKFIVIILIISILIGVLVKEYSSREIKKDDINVSKYIKYAD
                     LASKNNAQVNWKYVASIVAVLNKNNLKNVKDSQIQEVSDLFVKNFSKNNKINKLSDIL
                     DELEFSNRQKRLVDNYIDNLKDYGIKPERLKSDTKYMKFIDEIKTEAIQNYKDYKILP
                     SITIAQAIIESSWGKSTLAKQYSNLFGIKADAYWKGKSVTLETKEHLDTIIDDKFRIY
                     DDKNESIKDHAKFLATNKRYKNNGVFDAKTYIYQAKALEKAGYSTAKDENGNSIYAAR
                     LIELIQQYNLQLIDSEIQSEM"
BASE COUNT         7861 a         2155 c         3591 g         6412 t
ORIGIN      
        1 atatcttgaa taaattattc ttgaataaaa ttataaaaaa ttaaaatcac tagaaatatg
       61 ataaaataat ttaaaatacg catttcaatg acatttcaaa acaataaaat aataaaaaac
      121 aaacctaaat taagtctaaa tagcttttta gttaatttta gtagtaaaaa ataaaactta
      181 aaaagtgttt gacaattatg aattttgaga atataattaa attaaaatta tacacatata
      241 aaaatatact cctgaatcaa gaatgagata tttaagattc aaaatatata ttattatacg
      301 tgaataataa aaaagtaaga aaattttata agggaggggt agatgtgagt agtcaagaaa
      361 gcaaaccaaa aggaaatctt atatcaaatt ttagagatga tatgagagac cctaagaaaa
      421 gagcaatata cacatattca agttctataa acttagcgta caattttata ggttactttg
      481 tatcaactgt tacaaatatt tttttaactg atgtggcaaa acttggtgta attatggcag
      541 gtggtatgca aattatacaa tctttcataa aaattgctgt agctcctata acaggtacag
      601 tatttgacaa acaaccattc aaaaaaggaa agtattatcc atggcttaga tatgcaccag
      661 cagcgttagc attaacatat ggaatatttt tcatagttcc attaatgaaa ataagtccag
      721 cattactttt acctttgatg acagctttat tattaatagc atcttgtgct cagcaagtag
      781 ttttcactat aatttatgct atttaccctg tagttgctaa gacacctaga gaccgagtta
      841 taggctcaac tactacgaat atatttaaag aagttggtaa attcttagta ggtttttcat
      901 atccgttatt attagtttta tttgcagatg tattaggtgg agaaggaatg ggttatttag
      961 gtacctactt attctttgca gcaggatgcc ttttagtatt ttggttttct tcaacagaga
     1021 taataaaatc tggagcagaa gaagaagttc ttcaaaaaga agagaagcca aagattaaag
     1081 caagtgaaat ggcaaaagct ttattcacta atgtaccact tatgatggca ttttgtttag
     1141 aatttcttat atgtataaga tctataggat taggaccttt ggctccatat tattttaaat
     1201 atgtaataga agatgaacgt ggattagcag tatttttatc aatcatgcct ttggtaagtg
     1261 tagcattcat gtttttcgca ccagtgttta taaaaatctg tagagagcaa aaactagctt
     1321 caataatttc tttttctata tgtgcactat gccacttatt ggttgcatgg actccttggg
     1381 ggaaaactac tttaggagta actatgttgc tggcaattgg tggaggtttt tcaaatgtag
     1441 tatcaataat aaatcttaat ttctttgccg gttcttgtga ttatgggcat tggaaatcag
     1501 gaaaagactt acctggctta agtatgtcac tatatccagt tgcaatacaa gtaggagtat
     1561 tacttgcaac tactataaga acagttttaa tgaactcaat gggatatcaa gctgatatgg
     1621 tagtcacaga agcagttaaa tcaggtttta taaatatgat ttcttattct atggcaatac
     1681 ctttaataat agctgttgtt atagcaatac tatatccagt aagtgacaag aaattaaacc
     1741 aaataagaga agagttaaat caaagaaatg cttagttaaa agaaagttaa gtagatggtt
     1801 aatttaagct attaaagtaa gtagacgcaa tagcgtttat ataaatgaaa atacatatac
     1861 agagggggct tttaaaaatg atagaaaaat tattgagaaa taccgtaaaa gaattacatc
     1921 aatatgttcc aggtgaacca atagaaaaag ttaaggaaaa atatggtgta aaagaaataa
     1981 taaaattagc ttcaaatgaa aatcctctag gaccatcacc aaaagcaata gaagctatga
     2041 ttgaaatgtt aaaacaaggt caactttatc cagagccaga agctaacgaa cttagaagaa
     2101 aattagctga aaagctagat ttaaaaccag aaaattttat tgttgctaat ggtgcagata
     2161 acgttatcac tctaataggt gaggctttta taaatagagg agatgaagtt atatattgta
     2221 acccaacatt tccatcatat agaactgcaa ctataaaaaa tgaagggata ccagtagaag
     2281 tacctttaac agaagattat aagtatgatt tacaaggtat attagataag attacagata
     2341 aaacaaaatt aatatgtgta tgtaacccta ataatccaac aggaacaatt gtggatgata
     2401 aagagttaga agaattttta aagaaagtcc ctgaaaatat tataactata ttggatgaag
     2461 catatataga atttttaaca gttcctaatt atgtggatgg acttaagtat gtaagggaaa
     2521 attataacgt tatagtaaca agaactttct ctaaaatata tggtcttgca gggcttagag
     2581 taggatatgg tattgctaaa gatgagataa taagaacttt atttacagta aaagagcctt
     2641 tctctgcaaa tcgtgttgct ataagtggag caacagcagc acttgatgat gaagagttta
     2701 taaaagaaac atatgaatta aatagagttg gaatggctta ctttaaagaa gagtttacaa
     2761 aaatgggatt tgatgttgta gattcacaat caaatttcct ttatgtagat atgaaaacag
     2821 atatacctaa gttatttgaa gacttgaaaa aaagagggtt tgtaataaga ccaagtgcta
     2881 cacatgcacg tgtaagtatt ggaactatgg aagaaaataa gaaatttgta gcagttttaa
     2941 aggaaatatt aaatattaaa ggagagccaa gtattggata atagatagaa atattatgaa
     3001 acggggtgta gatatgaact taaaaataaa cgcagagaga tgtaaaagtt gtgaatactg
     3061 cgttatatct tgtaaaaaag gagcattaaa aatatcaagt aagataaaca aagaaggtta
     3121 tgctcatgta gaagttgatg agagtaaatg catactttgt ggaatttgct atcaggtgtg
     3181 tccagataat gtttttgaaa taattaaaga agaagcatgt caagaggctt agaaggagtt
     3241 gggataatat gaaaaagatg tggaagggga accacgccat tgcagaagca gccctaagag
     3301 gaggttgtga attttatgca ggatatccaa ttacaccaca aacagaggta attgaatttt
     3361 tatcacatag aatgtctgaa cttggaagaa cttttataca gtccgaaaat gagatggctg
     3421 ctatatatat ggtatatgga gcatatgcaa gtggaatgag gtctatgacg agttcttcag
     3481 gaccaggaat atctttaaaa caagaaggga tttcttactt atgtgcaaat cattaccctt
     3541 gtgtaatcgt aaatgtacag agatgggggc ctggtcttgg ctcattggac tcagcacaga
     3601 cagactatct aagagatact agagggggag gaaatggaga ttatcatttg atagtttatg
     3661 caccaaacag tattcaagag actgtagatt tgatgtataa ctcatttgat gtagcggaga
     3721 agtacagagt gcctgtcgaa attttgacag aagcagcttt aggtcaaatg atggaaccag
     3781 tagaatttcc agagtttaag aagagagaag gagatttagg ctggacttat gatggaagta
     3841 atagagacca tgcaaaggtt gcagataacc aaaagccaac tttttgtatg gagaaacgta
     3901 tgagaataac tgaaaatgaa caacaatggg aagattatca agtagaagat gcagaatatg
     3961 tgtttgtagc gttcggtata ccatcaagaa caactatgaa tgctgttaga agacttagag
     4021 aacaaggtga aaaagttgga ataataagac caataacagt atggcctttc ccatataaag
     4081 catttgaaaa ggtaagtaaa gatgtaaaag gatttatctc agtagaatca acagacacag
     4141 gtcaattagt agaagatgtt gctttaacct caaagaaagt atgtaaagaa aatgtacctg
     4201 tgtatggttt atttagtgga aatcatatac caaaaacatt gcaagtaatg gacacttata
     4261 gcaaaataaa atctggcgaa atcaaggagg tgttctaata tggctacaga aaaattaaca
     4321 cctagcgttg tttcaatacc aaacaagttt tgcccaggtt gtggtcatgg aatagtaaat
     4381 cgtataatag cagaggtaat agaagaacat ggatatgaaa aaaatcatgt attaacatta
     4441 ggagttggtt gtgtctgcaa tatgaatttt agctggaatg gtgataagat gcaaactgca
     4501 catggtagag cttcatctac agctatagga gttaaagtag cacttccaga tacattagta
     4561 atgacttacc aaggtgatgg agatgcttat gttataggtc tttctgaaac tttaaataca
     4621 gcatatagaa atcataatgt gactgtattt gtaataaaca ataataattt tgcaatgact
     4681 ggtggacaaa tgtcatggac cactatgccg ggtcaagtca caacaacaag tgtaaatgga
     4741 agagatataa agactactgg tagtccactg aaagttcctg agatggtggc aaacttcttt
     4801 gatgtagcat atgtagcaag aggttcagtt catagcccaa aggaaataat taatctaaaa
     4861 aaatatataa aaaatgcaat agaagctcaa ttaaatggag agggatattc cttagttgaa
     4921 atattagcac cttgtccaac taactggggt gtatcactag agaaatctat caaatggatg
     4981 gaagaagaaa tagtgccata ttatgctctt ggcgaattta agcaaaggga tggtgaatag
     5041 ttatggaaaa agagctagta tttgcagggt ttggtggtca aggagtttta actcttggtc
     5101 tgattgtagc tgagtcagca cttgaattgg ggaaacaagt aacttggatg cctgcatatg
     5161 gtccaactat gagaggtgga aaagcctata gtgtagtaaa gttttctgat gagagtatag
     5221 gtgggcctga tatggaagaa atagatgttt tagtagcaat gaataaacca tctttagatt
     5281 atataaattt agttaaagaa ggtggaacag tagttattaa tacatctgca atagatgaga
     5341 atgtaacatt aagagaagat ataagtgtag ttaaaataaa ttgtcaggaa ttagctcaaa
     5401 aagtaaacaa tccaaaagca gcaaatatag tagtacttgg agcattaatt gctaaaacag
     5461 ggttatttga aaaagaatta gctttaaaaa ctatgtgtga tttctttgag gaaaaaggaa
     5521 aaggaaagtt taatgttcaa aatgaagcag cattcatgga aggctataat aacgccattt
     5581 gataaattac ccttatctta agtgatttat ctcaagattt aataatcttt agtgccaaga
     5641 gaaacttcat cttgagataa aattcactta aaatcacaac tataaacata taggagcgtg
     5701 aatttatgag tttggaaaaa cttattagac caaaaagtat tgctatagta ggagtgactg
     5761 ataaacttgg ttttggaaga agtgcagcac ttagtatagt aaaaagtaag gaaacagata
     5821 gagtatatta tgttaatccc aaaagagaag aattgtttgg gagaaaatgt tataagacga
     5881 tacaagaagt tccagaagta gtagactgtg tagtagtatg tacacctaga aatgtagttc
     5941 catctgtatt aaaagattct ggagagttag gaacaaaggc agcagtggta tatgctagtg
     6001 gatttgcaga ggaaggtaca gaggaaggta cagatttaga aaatcaactt atagaaatat
     6061 caaatacata cgatatgaaa atattgggtc caaactgcat ggggttgcta aattgtatag
     6121 ataaggttaa tctatgggca ggaggttcta aatgggattt agatactaaa aaacctggta
     6181 taggaattgt aggtcaaagt ggatttataa ctgctgaaat tgtttcaagt gattatttta
     6241 atatatctta tggtttttca acaggaaatg gaaatatagt tacactagaa gatgcagtag
     6301 atttccttgt agatgatgat tatgcatcag taatagcaat ttaccttgaa ggtttaaaaa
     6361 atcctcaaaa atttatagat gctttaaaaa gggcagcaca aaaaagaaag ccagtaataa
     6421 tattgaaatc aggaaggtca gaaaaaggtg ctatttctgc tgcttctcat acaggaaatt
     6481 tagctggttc gagtaaagct tttgaaagta tttttgaaaa atatggagta atttctgtgg
     6541 aaaatttaga acagtttatg tgtttagcac aagcttttag tgttttagat ggtaatttac
     6601 ctgcaaattc taattttgca gcaataaact tctcaggagg agaaaatact atttgtgcag
     6661 atttagcaga agaaaatggt gtagaacttg cagaaatatc ttctgaaact aaagaagaaa
     6721 tgaaaaaata tcttccagga tttgcaacac ctaaaaatcc actagatgct acaacagcat
     6781 tattccatga aaaggatatg atagtaggtt tattacatac ctttgaaaag gatgatagtg
     6841 ttggatttac tatggtaggt gcaaatataa gagatgaaga aaatgaaatg catgaaaccc
     6901 tttgtaaagc tgtaagtgaa gctagagaac aaggattgaa aaaacctgtg tttgcagttc
     6961 ctacacttga aggaaataga tatttagatt ataggactag attagaagat aatcaagtgc
     7021 ctataatgtc atcagttgga actacattta cttgttttaa taaaatggct aagtttatag
     7081 attatgatta ttcaaaaaga actttagaat ttaaagctgt taagaaaaga gagtcaaata
     7141 atgtagtagc attatcagaa ttagatagta agattgagat gaaaaaatat ggagtaccag
     7201 ttccaggaca aggtaatgca aaaagtattg atgaattaga tgaaatctta aaatatatta
     7261 agtatcctgt tgttttaaaa ataaattctt ctgaaatatt gcacaaatct gatgttggag
     7321 gagttaaaat aggaattgag aatagagatg aggcagtaga tgcatataat gagattttaa
     7381 ctaatgtaaa aaaagcaaaa ccagatgcta atattgatgg tatattagtt caagaaatgg
     7441 tagaaagtgg tatagaaatt attattggta taactaatga tgaccaattt ggaccaatgt
     7501 tattagtcgg tttaggagga gtatttgtag aggtatttaa agatactaca ttatatccat
     7561 tacctataaa tcatgatgaa gctattatga tgcttaaaaa actaaaatca tttaagcttt
     7621 taaatggcta tagaggaagt gagccttgtg atattgatgc tcttgcagat atgatggtca
     7681 agttaggaaa atatgcttat gaaaataagg atgaagtcaa ggaaatagac ttaaatccag
     7741 tgtttgtata tcctaaagga aaaggcgtat gtgcagtaga tgccttaata gttaaatata
     7801 aatagtttat aagttttggt attcaaccat aattaaagca ccgactgaaa atcacatttt
     7861 gtaagttaga tagtgtgatt ttcagtcacc ccaaatttaa tttaaaaata ttttaaaatg
     7921 aaagtatagt tttaagttta attgtgaaat agcactgtat aaacaataaa atactacgta
     7981 taaaacgaat aataaaaggt gttttaatga taagaatcaa tcttgatttt cattaaaaca
     8041 ccttctttat tatattaaaa atttttaaac gttatattgt cacaggtggg tttgttggag
     8101 ctgcatatgt acgattagca aattcttggt caacaaagaa tagaccaccc tctccagcaa
     8161 gtttaacacg ttttatattg tcttcacaat ttgtttcttc ttctgcttgt tcagatataa
     8221 accaaagtaa gaattgagaa gttctaaagt ctgattcaga gtttgctaca gctgctaagt
     8281 tgtttattaa agctgtaacc tttttttcat gagctaacgt acgctcaaga atatccattg
     8341 cagaagtaaa gtctgaatct ggcattggga tagcatcaag ctgaaccttt cctcctacat
     8401 tatgtaagta tttgtaaaaa aacatagcgt ggtctgtctc ttctttatat tgaacataaa
     8461 accaattaga aaatccttta agtccttctg cttcaaggta agaagacata gaaagataaa
     8521 gatacgcaga atataattca tggttaatct gctcattaag taatttttcc attttagctg
     8581 aaatcatttt tatacctcca aattttaaat gctcttataa aatataataa tattaaatgg
     8641 aaaaatattc aataaaagtg tttaaatatt ttacatattt aataaaaatt tatactacca
     8701 ttaaaaaaat tataacttac aatggctata gagccaatta atggtgcatt tgctccaaaa
     8761 tttgaatgcc ttacacttat ttttttatat ttagaaaaac ttgctgaagc agtcaatttt
     8821 tttaataatg tattttctat aaatgtacca ggtatattaa agtcatagcc tattattata
     8881 gaactacaat caatcaatgt aagtgtatta actaatgcat atgatacgta tgtacaaaat
     8941 tcatcaagca aaaacatggc aagactatct ttattatttg cctcatctat taacttgact
     9001 aaagaaaaat ctttacagtt aattaatggg gagttaggat aaatatggct caatgattca
     9061 attcttttaa ttagattact gacacttgta taataatcta aacatccatt attaccacaa
     9121 ctgcacaatg gtccactaaa attaattgat gtatgtccta tttctccact ttgtcctagg
     9181 ttgccagtat gaagtttatt ttctagaact agaccagctc caataccatt cattatgtgt
     9241 aggtatatat aatttgatat atttttacct aaaccataca ttttttctgc taatgcaccc
     9301 gaattagcat catttatcaa aaatattggc aaatcagaca tttcttttat aaaatctact
     9361 atatttaggt ttgatacatt tccaaaatct gggggattta gtatggtacc atttatatca
     9421 tctactggac ctattgaaga aataccaatt ccaattatat ctctcttgtt gattttcatt
     9481 attttagtaa acattctttt tattatatct tttaaaacat catttgatag acatttgggg
     9541 taagtttcag aaagttgttt tacaatatta ccttttaaat ctgaaataat taccttacat
     9601 atatttcttc ttattaggat tccacaaata caaggcgata tattagaaat atctaataaa
     9661 ataggtttac gacctgatga atgtgcattt aaagttgatg actctatttc cctaatcata
     9721 ttttcattaa taagttcagt aactagattt gataaagtca ttttagtaag tcctgtagac
     9781 ttagctaaat caactctgga cataggtgta tttgtagaaa gtaatttcaa tattattaac
     9841 ttatttttaa tttttacatc tttgatgtta gaaccttgtt tgttactcat cataaatctc
     9901 cttaaataaa gttaagtgtt ttatttattt tcaagtatac tatcacctta taatagagta
     9961 acattttttt acttgaaaat atcattaatt agaatatatc acattatata tcataaaata
    10021 tataaaaaaa tgttagaatt aaattaaaag tgaaaagtag attgatatat aaatagtaaa
    10081 tacttaatta aaaaaagata atgatagcaa taattattgt taccaagaat ctactacttc
    10141 aagtgttacc ttaggtattt aagttgatag tggtttgcac gtaataaact tgatgtaata
    10201 tatattctta ataatatcga taaaagattt acttaaaaat aatatagatt atgtaaacat
    10261 ataatctatt tattgtatac aataaaattt cattttgtaa aacagtgaat taaatatgta
    10321 atatagatat cgatttttat tacaaattgt tactaaatat aggtacatta gaacaaaaat
    10381 ctagtaaatt gtaactaaaa tgtaaatttt tcctttaatc tatacaatat tatggaaact
    10441 ttttgtaatt tatgatataa taacaaatat ataattatta aattataata aatgactata
    10501 gcgtagatgt aatactatgt tatagtcatt tttgaattaa acttgatata tcaaggggga
    10561 agaatatgag aacaattaga agagttttag cattaggttt aacattagct atatttctaa
    10621 taaatgtacc taatgtagat gcattaacat cagatacaat taaaggtaac aatatatatg
    10681 agacggctgg attaatagca gataaaaaga gttatgatac agcaattatg gtaaatatgg
    10741 ataattctat agcagatggt ctttcagcaa gtggtcttgc aggtgctgtt gatgctccaa
    10801 ttttgcttgc acaaaaaaat aagataccaa atgaaacaaa acaaagatta aaaaatgtta
    10861 aaaagatata cataataggt aaagaattat caataagtaa gtcagtagaa actgaactaa
    10921 aaaacacagg ggcacaggta actagattgg gtggagatga cagaataaag actagttata
    10981 gtgttgctaa agaggtaaat ggtatcaaaa aagttgatga agtgatatta actaatgcat
    11041 ataaaggaga agcagataca ataagtgctg cacctgtatc agtaagagat atagctccta
    11101 tagtacttac agatggaaag agtgtacctt tttcaacaag caatgtaaaa acatatgcag
    11161 taggtgggag tatatcaatg agcactagtt tagttaataa aactaatgct aaaagacttg
    11221 gtggttcaga tagatatgat acaaataaga aagttataaa agagttttat ccagatgcat
    11281 cagaatttta tttgagtgat ggatatgatt tagtaaatgc acttacaggt tctacaattg
    11341 ctaaggaaaa tccaattgta ttggtgtcag aaagtagtga taagtctata ttagcaggag
    11401 cagataagat tactagatta ggttcaataa gtgacagtgt gtataataag tgtgtttctg
    11461 ctgcacaaaa taatggcgat tcgtctacaa aaggtgagtc acctatgaaa aatgagacaa
    11521 gcatattagg tcagccaaca gctagtttag aagcgtgctt aaaatgggca aaatctaaaa
    11581 aagctaatga tttatttata gagttaatac caatattata tgatactgct gttcaggaag
    11641 gtgttaatcc tgttttggca gtagctcaat ctgcaaaaga aactggtttt tgtaattttg
    11701 gtggagtatt agatgcatca tttaagaatc cttgtggact taaaacttct gtaggaggtt
    11761 ctgatactga taagaatgcc cattcaagat ttgatacttg ggaagaagga atattagctc
    11821 aaattcaaca tttatgctta tatgcaggac aagatggtta cccactttca aatccagtag
    11881 accctagaca tgaaaaatct ttatttggta aggctaaaac agttgaaagt ttatctaata
    11941 attgggctgg aggtcaatat ggacaagatt tagtaagaat gatgggagaa attgaggcaa
    12001 caaaataatt gaagattatc aaatatccaa taaataagga ttgattatta tgaaaaagag
    12061 taatattttt agtatcatat ttcctacagt cataatggtg ctaatgtttt taacttttgc
    12121 tacagatata tttaatattc cagatattca atctaaaagt atttttgttg tgggaatggt
    12181 tttgattttt ccaatttctt ttttgataca agggataatt tgtgtattaa ataagactaa
    12241 ttggatttta tctcttattg tgtctttagt aacttatata gtattaatgt atatattttt
    12301 aaatgattct gcatatatat atgttttact ttatacagct ttttatatga ttggacatat
    12361 aacagctaaa ctctattaca aaattaagac ttttaaaaat taaattgaag tatataaaag
    12421 taacattagg agaagtatcc ttaatgattt tctaaaatca gaaataggtg cttctctttt
    12481 ttgtaaaaat aaaagtatgt aaataaaatt taaccattat aattttcttt taacaaatgt
    12541 atacaataaa cttgttgtat aattaagata gataaaataa agggagggat aatatgaatt
    12601 taatagataa tcatattcat actaattttt caagtgatgg aaaggattcc atggaagata
    12661 caataaaaaa agctataagt attggtgtta gatatttgac ttttacagac catttagaac
    12721 atgatgaaga tagaggattt tgcataaatt ataatgacta tgttccagta tttaataagt
    12781 ttaaagaaaa atataaaaag gacatagagt tattactagg tgttgaagtg ggttacagaa
    12841 aacatctaaa aaatgaaata gaagaaataa taaattctaa tccttttgat tttgtattgt
    12901 gctcaactca tacaattgac aatgtacctg ttccatcaaa ggagtatttt aaaggtctta
    12961 gcaaagaaga tgcgtattat aaatatttta atagcatact tgaaactaat cgtgaatttg
    13021 gagattacaa tatatatggt catttggatt atatatctag gtatggaata tattcagata
    13081 atagagttat atacaatgac tttaaagatg ttattgatga ggtcttaaag tcaataatca
    13141 ataatgggag tggtatagag ctaaatactt ctggttatag atatggatta aatgctatac
    13201 atccaaatga agatattcta aaaagatata aagaacttgg aggatttata gttactgtag
    13261 gttctgattc tcatagggta gaagatatat gtaaagattt tgatgtggcc tatgatatgc
    13321 ttaagtatct tgactttaaa tatgtatctt tatttaaaga aagagaaact tattttgtaa
    13381 atatagaaaa agttaaatct aacaatatag cttagagtgt gttttgaagt aaattaatgg
    13441 atagttaaaa agttaatagt tataatattg tatcctctag aaaaatacta gaggttttta
    13501 ttttgctaaa ataactaaat agaattaaat ttaaatagta tagtttattt taaattgaat
    13561 agtttattgt tgatatattt tactattata tatttttatt gtgatataat agtaaaatat
    13621 attaacctat ctttagatta tataaattat tataaaggag ggaaatttta aaatgtctaa
    13681 taaaaataaa gaaaatataa ctttaagtaa tcaaatcaaa ggaacaattc aaaatagttt
    13741 aacaaaagaa gctatattac atataccaat gagcaattat gcctatggtt atgatagaga
    13801 aacactacat ataagactta gaactaaaaa aaatgaagcg aaaagagtaa ttttacgaat
    13861 aggagaccaa tatgtgtggg ataaaggagg tgcaggagga ggaaatttaa atgcatctgg
    13921 agttggttgg tctggtggaa caaatatagt aatgagtaaa gaagtagaaa ctgaattatt
    13981 tgactattgg atagctaagt gtaagccttt aaataaacgc tcacgatatg gctttataat
    14041 agaaggtcaa gaggaaaaac ttttatttac agaaaaaaga ataatagagt tgggaaatga
    14101 aaatgatgaa aaggaattat gtgaaatagg taattttttt ggatatccat atttaaatta
    14161 tatagatata cctaaagtgc caaattgggt gaaagatact gtttggtatc agatatttcc
    14221 agatagattt gcaaatggtg acccgtctat aaacccagaa ggagtagata aatggggagc
    14281 tattccaacc agagataatt ttacaggtgg agatttacaa ggtgtgatag aacacttaga
    14341 ttatttgagt gatttgggaa taaacggaat ttacttttgc cctattacaa ttggaaaaac
    14401 caatcataga tatgatacgg tagattatat ggaggtagac cctacattag gagataaaga
    14461 gactttaaaa aaactaatag aagaagcgca taagagaaat ataaaaataa tgttggatgc
    14521 tgtttttaat catataggat attattctaa acagtggcaa gatgtagttc aaaataagga
    14581 aaattctcga tataaaaact ggttttatat aaaagatatg agtaaaattg atactccaat
    14641 agaacaaata gatgaaaaaa atatacctta tgaaaccttt gggtgtgaaa aatatatgcc
    14701 taaacttaat acagaaaatt cagaagtaat aaaatattta ttggatgtag gcaagtactg
    14761 gatacaggaa tttgatatag atgcgtggag attagatgtt tcaaatgaag tagaccatgt
    14821 tttttggaga aagtttagag aagaagtcaa aaaagtaaaa ccagacattt atatattggg
    14881 agaaatttgg catggtagtt taccatggct aatgggtgac caatttgatt cagttatgaa
    14941 ttacttgatg tcagaagcca tgaaaaaatt cttttgtaca gatgagataa acgccgaaga
    15001 atttaagtat atgataaatg atgtaatggt aagttatcca atacaagtta gtgaagttat
    15061 ttttaattta cttggaagtc acgatactac aagaatattg acttatgcta atggaaatat
    15121 tgatagattt aaacttgcat atatgtttat gtttgtacaa acaggatgtc cttgtatata
    15181 ctatggtgat gaaatcggaa tggaaggaga attaagttca atatctgaag gtcaaagaaa
    15241 atgtatggaa tggaatgaag aaaaatggaa taaggatata tttgatttta tgaagaagat
    15301 tattagactt cgtaaagaaa ataaagaact taggtctata tcaaatgaat gggtgttagc
    15361 agataaggaa aatggaacga ttatattgaa aaaagaatct atttctataa taataaataa
    15421 ttcatctaaa aatataattt tgacgttacc agattattta gcaaataaaa aagtaaaaga
    15481 tttatatgaa gaagaaatag ttgatttaaa agaagaacta atgttagaga aatacaagtt
    15541 cattatttta aaataataca aaaaagtatt tattttagat ttcatgttaa attattatac
    15601 agtttaaata agtctttata aacgataaaa aaatatggtc tacaagtgag tgaattgaaa
    15661 gtagatttta aattaaagac tgagttagag tagataattt tataaataat atcttaaata
    15721 caagatagaa aataaattga ttattagtct aaaaatttct tgtagaaaga ggaaataaga
    15781 atgattgaag catttatatt tgatttagat ggtgtaatta cagatactgc atattatcac
    15841 tatatggctt ggagaaaact agcccataaa gttgggatag atatagacac aaaatttaat
    15901 gaatctttaa aaggcataag tagaatggag tcattggaca ggatattaga atttggaaat
    15961 aagaaatatt cattttcaga agaagaaaaa gtgagaatgg ctgaagaaaa aaataattac
    16021 tatgtatcat tgatagatga gataacttca aatgatattt tgccaggtat agaaagcttg
    16081 ttaattgatg taaaatctaa taatataaag ataggtctat cttctgcaag taagaatgca
    16141 ataaatgtat taaatcattt gggtataagt gacaaatttg attttatagc tgatgcagga
    16201 aaatgtaaaa acaataaacc acatccagag atatttctta tgtcagcgaa agggcttaat
    16261 gtaaatccac aaaattgtat agggatagag gatgcaagtg caggtataga cgctataaac
    16321 tcagctaata tgttttctgt tggtgttgga aattatgaaa acttaaaaaa agcaaattta
    16381 gttgtagatt caacaaatca attaaagttt gaatatatac aagaaaagta taatgagtat
    16441 atagttagga gaattatatg aaatgtttat ttagtaatgt agatgagtgg aagattatac
    16501 aagataagat tgaaatcaaa gaaaatagat tagcagagtc cataatgagt ataggcaatg
    16561 gatatatggg tatgagagga aactatgagg aaaattatag tggagataca cacaaggggt
    16621 cttatatagc tggagtatgg tttccagata aaactcgtgt tggttggtgg aaaaatgggt
    16681 atccagaata ctttggtaaa attcctaatt cagtcaacta tataggtgta agaattttca
    16741 tagatgatgt agaattagat ttagcaaaat gtaaagtaga agatttttat agagaattag
    16801 atatgaaaaa tggtatttta aatcgtaggt ttattgtaaa tataaatgat aaaaaatttg
    16861 aagttagggt tgctaggttt ttaagtatat ctgttaagga acttgcagta attaaataca
    16921 gtataaaatc attaaattct aatactaaaa taaaatttgt accatattta gattcaaata
    16981 taaaaaatga agattcaaac tatgaggaaa agttttggaa tggaatttct tcaagttctt
    17041 tagaatataa aggtagtatt ctttctcgaa caaaggagaa tgcatttaat acaccagtat
    17101 tcactgtggg ttcaatgatg tatattaaga caaatggtga tgtagaagct gtatctcatg
    17161 agagtgatta taattactgt gaaaattcga taacaatgga tgttttaaaa aatgaggttg
    17221 caagtataga aaaatatgta tctataactt caactagaga ttataaggaa agtgagctat
    17281 taagaaaatg tgaagacatt ttaaatagag aactatctaa aagttatgat gatatattaa
    17341 atgaacatac aaagttatgg aataaaagat gggaaagtgc agatgtaaaa ataaatggag
    17401 ataaaagtag ccaacaaggt ataagatata atttattcca actattttca acatattatg
    17461 gagaagattc gcgattaaat ataggtccaa aaggatttac tggtgaaaag tatggaggag
    17521 ctacttattg ggatacagaa gcgttttgtg ttccagtata tctaggtgta gcagataagg
    17581 aggtaactag aaatctttta gaatataggt acaatcagtt agaacaggca aaggataatg
    17641 caaaaaaact agggcttaaa ggtgctttat atccaatggt aacatttgat ggagtagaat
    17701 gtcataatga atgggagata acatttgagg aaatccaccg aaatggaagt atagtatatg
    17761 caatatataa ctatacaaat tatacaggtg actataaata tataaaagaa aaaggaatag
    17821 atgtaataat agaaatagct agattttggg caagtagagt tcatttgtct acaaaaaaag
    17881 atttgtatat gatacatgga gtaacaggtc caaacgagta tgaaaacaat atcaataata
    17941 attggtatac taattatata gctaaatggt gtttagatta tgctgtagaa aatatcttac
    18001 gattagagaa agagtgtaat gaatgtattg acagaaataa tgtgactagg gaagaagttg
    18061 agttttggaa aataatatca aataaaatgt atctgccgta tgatgaggaa ctacaaataa
    18121 taattcaaaa tgataatttt ttagataaag aatttgtaga agtaaaggat ttaccaaaag
    18181 aaaattttcc tcttaatcaa aattggtctt gggataagat tcttaggtcg tgttttataa
    18241 aacaagcaga tgtattacag ggaatttact attttggaaa tagatttact aaagaagaaa
    18301 aaaagagaaa ttttgacttc tatgaaaaat atactgtaca tgaatcttct ttatcttcta
    18361 gtatttattc tattattgcc tcagaaatag ataacctaga aaaggcttat gaattatatt
    18421 caagaacagc taggcttgat ttagataatt acaataatga tacaaatgat ggactgcaca
    18481 taacttcaat gtctggttca tggctttcca ttgtacatgg atttgcaggc atgagaacat
    18541 ggaatgaaac tctatctttt gaccctaagt tgccaaaaga gtggaaaaat tattctttca
    18601 atataaatta tagagataat attattaatg tagatgtatg tagtgattta attaaaatag
    18661 aaaatttaaa aggtagacca ataaaaatta ttgtatatgg gaaaaaatat atattagaaa
    18721 aatgtataaa aattgataaa tagatttaat aatattttta ttatataaat agttaaaata
    18781 agctatctaa ttatttattt attttaacta ttttgtgtga tagaaaacta tatattataa
    18841 caatagtagt gcttttaatt aaatatattt cataaatctt cataaaatct tcaaaatttc
    18901 gtaaagaata tgtcacaaaa gtaaggtata ttatattcag cagatagtat aagggaggac
    18961 aatatttatg aagaataaaa aattcattgt tataatactg ataatatcaa ttttaatagg
    19021 tgtattagtg aaggaatatt catctagaga gataaaaaag gatgatataa atgtcagtaa
    19081 gtatataaaa tatgctgatt tagcaagtaa aaataatgca caagttaact ggaagtatgt
    19141 agcttccatt gttgctgtgt taaataaaaa taacttaaaa aacgttaagg attcacagat
    19201 acaagaagta tcagatttat ttgttaagaa tttttctaaa aataataaaa taaataagtt
    19261 aagtgatatt ttggatgagt tagaatttag taatagacaa aaaagattgg ttgataatta
    19321 tatagacaat cttaaggatt atggtataaa accagaaaga ttgaagtctg atacaaaata
    19381 tatgaagttt attgatgaaa ttaaaacaga agcaatacaa aattataagg attataaaat
    19441 acttccatct ataactattg cacaagctat aatagaatct agctggggca agtcaacttt
    19501 ggcaaaacaa tatagcaatc tatttggtat aaaggctgac gcttattgga aaggtaagtc
    19561 agtgacttta gaaacgaaag aacatttaga tacaattata gatgataaat ttagaatata
    19621 tgatgataaa aatgaatcta taaaagacca tgcaaaattt ttagccacaa ataaaaggta
    19681 taaaaacaat ggtgtatttg atgcaaaaac gtatatatat caagctaaag cattagaaaa
    19741 ggcaggttat agtactgcga aggatgaaaa tggcaatagt atatatgcag ctcgtctaat
    19801 agaattaatt caacagtata atcttcaatt aatagacagt gaaattcaaa gtgaaatgta
    19861 actttgatta aatttttatt gataaggcta tgatttttaa aatcatagcc ttattttgac
    19921 atgcttttac ttgtaattat taaatcgata tcattatctt tcaaaattta ctttatactg
    19981 taaatcaaat tatttaagtt aaaacttgga attatttat
//
LOCUS       DAJMZY010000076        19747 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.076, whole genome shotgun sequence.
ACCESSION   DAJMZY010000076 DAJMZY010000000
VERSION     DAJMZY010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 19747)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19747)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19747
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.076"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            312..1691
                     /locus_tag="OE968_002601"
     CDS             312..1691
                     /locus_tag="OE968_002601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016290023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HCP7219875.1"
                     /translation="MAQDKIVVEILENIGGKENIKEVAHCMTRLRIKVCDSSQVNQEK
                     LKKIKGVLGLVLKGEQYQIVIGPNVSQVYNTLNEVIGIIPEKDSKKTISEGKQNSIAK
                     ILDTIAGIFNPIVPALAGAGLIKAILALLVASKFLSADSETYIILNTISDGVFSFLPF
                     MLAYSAAKIFKMNTYVAVAIAGAMLHPNFINLIQQGLTKISFIGIPMSLIQYNGSVFP
                     IVLTIWFASYIEKGVDKITPKALKIILVPALTILFAAPIALIIIGPIAQMLGNYIAGG
                     ASILFERGGIFAGLIYGGIYSFMVVTGLHHGMVPVLVDGITRYGFNYISPVSGSSNMA
                     QAGSAFGVWLKAKDKDLKAVAATATISALTGVTEPAIYGVNLRLKKPFLCAAIGGAAG
                     GGFAAYFQCKAFAMGGPSFLTLPMFIGEGGHVGLVAIAFTIAFIVSAIATYIVGFEEE
                     VTADSHANL"
     gene            1735..2469
                     /locus_tag="OE968_002602"
     CDS             1735..2469
                     /locus_tag="OE968_002602"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010990049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HCP7219876.1"
                     /translation="MKIYLTKDYEEMSQVAAQMVLKYMYSNDNKRINLSITAGQTPKR
                     TYEILSEFVKNKPYFENVHYYNFDEIPIKGEKVGVTIRNLTNMYFREAQIPEERIHVL
                     DENNYQGFDRKIEADGGIDMVLMGLGWDGHFCGNLSGTVNSFDEETRAVSTYITDDMA
                     KLLTKSVGGNPEKLFDYYVTYGPKTIMHCKNIIMIVNGKHKAQILKQTLFGPLDLLCP
                     SSLLRLHPNFTLIVDEEAASEIKDLI"
     gene            2558..3757
                     /locus_tag="OE968_002603"
     CDS             2558..3757
                     /locus_tag="OE968_002603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006875852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HCP7219877.1"
                     /translation="MYNHMKKVFQGLEGGLFSSVEKADVGDSYQKLGEQGVSLMGWAD
                     PFFPDYCIPRHILDAATLAISSNMSTHYTAPVGNDLLKIEIAEKLKEVNNLDVDFKRN
                     ILITPGSDSGLYYSMLPFINEGDEVLIPTPCYPNNIQNTKLMGGVPIFVELKESDGYQ
                     IDITEFEKRLTNKTKLVVLTHPNNPTTTIFNKESLEKLAKFIIDNDLILICDQAFEDF
                     TFENELITPASLEGMFERTVTIFSTSKGMGLSGFRVAYMVCSDKLMDKYYGAAVTVLG
                     ATNTVAQMSTIEAFKDRSFMEDFERVFDKRRQEAYKIINEIPNVSMQMPESGFLGWIN
                     VSKLGTSSEIQKYLVDEAKVCINDGINYGPGGEGHLRIILGSYKDDSKVIGALNRIKD
                     ALIKKQQ"
     gene            3781..4263
                     /locus_tag="OE968_002604"
     CDS             3781..4263
                     /locus_tag="OE968_002604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015529974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HCP7219878.1"
                     /translation="MLSIFKSKKNDNKLKAFASGKVIPIEDVDDNVFSSKMLGDGIAI
                     YPTNEYVVAPCDAEVNIIMKDTKHAVGIKLFNGMEILFHVGIDTVSMNGEGFEIFVSP
                     GDKIKRGDKLISFNSKLIKEEGLQDVVIMVVTNSEQYKNIKYHIGLEAVIDDTIIAEI
                     "
     gene            complement(4581..5178)
                     /locus_tag="OE968_002605"
                     /pseudo
     CDS             complement(4581..5178)
                     /locus_tag="OE968_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816433.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(5422..5850)
                     /locus_tag="OE968_002606"
     CDS             complement(5422..5850)
                     /locus_tag="OE968_002606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219879.1"
                     /translation="MKIHSIQNLTLDTRNLIKKYSLTLNEDLIWEFKHGKYHTIKYFT
                     HKFAVKESVLALLFNIHKLCYAKIKYFESSFSKYEPYKYSYQNEFVKCEMYDMNFMFH
                     KYSNIMIDLRNLQEIKTIEEFRLFCDYLESFEDNLQDLII"
     gene            complement(6251..6712)
                     /locus_tag="OE968_002607"
     CDS             complement(6251..6712)
                     /locus_tag="OE968_002607"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HCP7219880.1"
                     /translation="MIYEGKLIGKDLKIGIINSRFNEFITSKLLSGAEDCLLRHDVSP
                     ENIEIVWVPGAFEIPLVAQKMAKSGKYDAIICLGCVIRGATSHYDYVCSEVSKGIAKV
                     SLDSELPVIFGIVTTENIEQAIERAGTKAGNKGYDCAMNALEMANLFKSLD"
     gene            complement(6817..8010)
                     /locus_tag="OE968_002608"
     CDS             complement(6817..8010)
                     /locus_tag="OE968_002608"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HCP7219881.1"
                     /translation="MFNTIEEAIEDIKNGKMVIVVDDESRENEGDLLMAAEMATPESI
                     NFMATYGRGLICLPATEKKFKSLNIPLMVRENTDTFQTAFTVTIDGADTLTGISAYER
                     AETVKLFCDENSTSKDFKTPGHIFPLIAKTGGVLVRDGHTEASVDLARLAGFKEIGLI
                     CEIMKDDGTMARVDDLMIFKEKHNLKIITIKDLIEYRKINETTIEKVSSAFLPTKYGN
                     FEIIGYRDTYSNEEHIALTYGNINIENTLVRLHSECLTGDVFHSLKCDCGLQLESSMK
                     KIVENGSGVLIYMKQEGRGIGLLNKIKAYKLQEEGYDTVEANLMLGFEEDMRDFYMAA
                     QILKNLNIKSINLLSNNPDKINQLEKYGIKIENRIPINEEINDFNKLYLKTKKDKMGH
                     LLDII"
     gene            complement(8033..8698)
                     /locus_tag="OE968_002609"
     CDS             complement(8033..8698)
                     /locus_tag="OE968_002609"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HCP7219882.1"
                     /translation="MFTGIVEEVGILRKITANGKSGKVTILSNKILDGTNLGDSIAVN
                     GVCLTVSNLGKNEFTADVMMETIRSTNLGLLNANDKVNLERAMSLSSRFGGHIVTGHV
                     DGKGTICKFEKDENAVLVSIRPDKKLLSSMILKGSVAIDGVSLTISYLDDEIFKVSII
                     PHTKINTILLTKNVGDFVNLESDVIGKYVNNFMANNYKELNSNSSNHKSNIDKDFLFK
                     NGF"
     gene            complement(8732..9844)
                     /gene="ribD"
                     /locus_tag="OE968_002610"
     CDS             complement(8732..9844)
                     /gene="ribD"
                     /locus_tag="OE968_002610"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HCP7219883.1"
                     /translation="MNFVNQKEKDIYYMKKAIELAKNGEGFVNPNPLVGCVIVKDSNI
                     IGKGYHEKFGSNHAEVNAINSAKQSLKDSTLYVNLEPCSHYGKTPPCVDKIIQNKIKR
                     VVISTLDPNPLVCGNGVKKLKDNNIDVTVGILEDEARDLNEAFFYHIKNKRPLCIVKS
                     AVSLDGKIATKSLESKWISNESSRYLTHKYRNKYQSIMVGINTVLNDNPLLTCRLNQE
                     KVSHPTRIVIDTHLKLPLNSNLVKDKTSKTIVFTCCKESIKLSMLKENNVETIISPSK
                     NNLVDLEFVMYKLGELNIDSVLVEGGATLNDSLFRNKLVDKVKLFLSPKIIGGKDAPT
                     FVSGEGINHLSDSTQLTINNVTLIDGDILIESDVLN"
     regulatory      complement(9976..10097)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            10286..12768
                     /gene="recQ"
                     /locus_tag="OE968_002611"
                     /pseudo
     CDS             10286..12768
                     /gene="recQ"
                     /locus_tag="OE968_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729557.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
     regulatory      12857..12968
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            13110..14411
                     /gene="thiC"
                     /locus_tag="OE968_002612"
     CDS             13110..14411
                     /gene="thiC"
                     /locus_tag="OE968_002612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomethylpyrimidine synthase ThiC"
                     /protein_id="HCP7219884.1"
                     /translation="MNYTTQMDAARKGIITKEMEIVSQKEQVDVNELRELIANGQVVI
                     PANKNHKSLSAEGVGKNLRTKINVNLGISRDCKDIEKELEKVRVAIDMKAEAIMDLSN
                     YGKTREFREKVVEMSPAMIGSVPMYDAVGYLEKELKDITEEEFLNVIRQHAIDGVDFI
                     TIHAGLTRSVCQKIKNHERLTHIVSRGGSLLFAWMELNNKENPIYTNFDKILDICEEY
                     DVTLSLGDACRPGCIKDSTDGVQIQELVVLGELTKRAWERNVQVMIEGPGHMAIDEIE
                     ANVVLEKRLCHGAPFYVLGPLVTDIAPGYDHITSAIGGALACAKGVDFLCYVTPAEHL
                     RLPNLDDMKEGIIAAKIAAHAGDIAKNVKGAREWDNKMSKARADLDWCEMFRLAIDPE
                     KAKRYRDESTPTHEDSCTMCGKMCSMRTVKKILNNEELNLI"
     gene            14465..14659
                     /gene="thiS"
                     /locus_tag="OE968_002613"
     CDS             14465..14659
                     /gene="thiS"
                     /locus_tag="OE968_002613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfur carrier protein ThiS"
                     /protein_id="HCP7219885.1"
                     /translation="MKVNGKEIEFEKDLTVIDLLNKYNLKSDRVVVEVNLEIIEESNY
                     NTYVLKDEDIVELISFIGGG"
     gene            14652..15455
                     /gene="thiF"
                     /locus_tag="OE968_002614"
     CDS             14652..15455
                     /gene="thiF"
                     /locus_tag="OE968_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine biosynthesis protein ThiF"
                     /protein_id="HCP7219886.1"
                     /translation="MVKIKIFVNELLTDVEENTTAYKVRDSYNNKCDVLVLNGYPIKT
                     DMTLCENDKLTLIQKGVKPSLDELESLLIARHTPNIHNKLKKGKVAILGLGGLGSNIA
                     ISLARIGVGELLLIDYDVVEPSNLNRQQYFIDDIGKLKTDAMIENIKKINPFIKLNKR
                     DIFLNKNNMDTIKDSDLIIEAFDDASCKAQVCNYVLINLKDKYLIASSGMAGYYDSNI
                     ITTKKIKDRFYICGDFVNEAKFGEGLMAPRVAICANHMANLATQILIDM"
     gene            15518..16288
                     /locus_tag="OE968_002615"
     CDS             15518..16288
                     /locus_tag="OE968_002615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018592874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiazole synthase"
                     /protein_id="HCP7219887.1"
                     /translation="MDKLVLGGHEFNSRLLVGTGKYGSNNILPEVIKESGSEIITMAL
                     RRVDLDNKQENILTYIPKEMTILPNTSGATNAEEAVRIARISRKMGCGDFIKIEVISD
                     TRYLLPDNEETIKATKILADEGFIVLPYMTPDLYAGRRLIEANAAAVMPLGAPIGSNR
                     GLQMKEMIRIMIDELDIPIIVDAGIGKPSQAMEAMEMGADAVLVNTAIASAGDPVQMA
                     RAFKLAVEGGREAYIAKTGNVSEFANASSPLTGFLGNL"
     gene            16305..17408
                     /gene="thiH"
                     /locus_tag="OE968_002616"
     CDS             16305..17408
                     /gene="thiH"
                     /locus_tag="OE968_002616"
                     /EC_number="4.1.99.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-iminoacetate synthase ThiH"
                     /protein_id="HCP7219888.1"
                     /translation="MSFYDVIEKYRDFDFDGYLNNVTDNDVLRSLSKDKLEDFDILNL
                     LSKTAVKHLEDMAQKAHKLSVQYFGKTVCLYTPMYIANYCVNQCVYCSYNIKSGIKRK
                     KLTMDEIREEGEAISKEGFKHLLVLTGESSFHSSVEYIGEAIEILREKFPSIGIEVYP
                     MEVEEYKYIVDKGVEGLTVYQETYDEEIYKRVHIKGPKSNYKFRLDAPERGAKAGMRT
                     LSIGALLGLNDFRKETFFTILHGKYLKTKYPHIELSYSTPRMRPFKGCFEELVDISDT
                     DLVQAMVCMRLFDPHAAINISTRENLEMRSHIIPLGVTKLSAGVSTDVGGHSQDEHDT
                     AQFKINDESTVKDVEKMLNSIGYQHVFKDWERF"
     gene            17409..18098
                     /locus_tag="OE968_002617"
     CDS             17409..18098
                     /locus_tag="OE968_002617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HCP7219889.1"
                     /translation="MYLITNRKLCSEERYLEVIKESILSGVENIIIREKDLEYQELRK
                     LYMKIKTKINCIDFQEQISDESLKTNINQKECRNKFKVNFIINSNIEFFEKVDCQGIH
                     LPFKLFLNLIENKYNFNENKILGLSLHKVEEVDYLEKLIRNQNIKIDYITLSHIYETK
                     CKEGLNPKGIELLKEAKKITDIKIIALGGILPSNVKETLKYCDDFAIMSTIMRSKDIK
                     KTISNYNEKLN"
     gene            18286..19680
                     /gene="yfcC"
                     /locus_tag="OE968_002618"
     CDS             18286..19680
                     /gene="yfcC"
                     /locus_tag="OE968_002618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HCP7219890.1"
                     /translation="MTDSKKKRFIIPHTFTIIFLLIVLMAILTWIVPSGEFSREDVEG
                     RMVVVPGTYQSVESNPQGFADVFKAPIEGFIDSAEVVGFVLIVGGAFGIVNRTGAIEA
                     GIASVISKFKGKELLIIPISMILFGLGGTTFGMAEETLPFYMIFVPLMTSLGYDSLTA
                     IAIVFIGAAAGAAASTINPFSVGIAQALAQLAPGSGVTYRVVIFIAYILISIAFVMYY
                     AKKVKENPESSIVYEIDKNNKSILNQTSTEIKEFTFKEVSVLAIFGIGMAIMIWGVLS
                     QGWYIPEISMCFAAIGVLSGLVGRLSQIEISESFIDGAKDLASAALAIALARGIVIIA
                     QNGFIIDTILNSAAAFLGGLPKVIFVYLSFFLEAALAFLIPSSSGLASLTVPVLAPLG
                     DLVNISAQVIVTAYQFGVGLTNFITPTSGVLMGALAVAHIPFSKWVRFIMPILLILTA
                     VSLVFLTIGIYIGF"
BASE COUNT         7411 a         2365 c         3286 g         6685 t
ORIGIN      
        1 gtattattga cagaatatat aaaatgttaa aaatagtatc taggaattaa acaaattaaa
       61 ggactagtga tttgaatttt tttagtataa tatgtgactt ccaattaata tttattaaac
      121 accaataaaa ttgtaaatat gcttaatgat atactttagc gatgaagtga aaatatttta
      181 tttttatgat taacctatag gaattaattt agcatactgt ttagctagta aatctaaata
      241 aattttagct ttagctgata tcatgttgaa taaagtttct attggatttt gtataacaaa
      301 ggagtgggga gatggcacaa gataaaattg tggttgaaat tttagaaaac attggtggta
      361 aggaaaatat taaggaagta gcacattgta tgactagact gagaataaag gtatgtgata
      421 gttctcaggt aaatcaggaa aaactaaaga aaataaaagg tgtactaggt cttgtattaa
      481 aaggtgagca atatcaaatt gttataggtc ctaatgtatc acaagtgtat aatactctta
      541 atgaagttat aggaattata cctgagaagg atagtaaaaa aacaatatct gaaggtaaac
      601 aaaatagtat tgcaaaaata ttagatacta ttgcaggtat ttttaatcct atagttccag
      661 cattagcggg tgcaggtcta ataaaagcta tattagcatt actagtagca tcaaagtttt
      721 tatctgcaga tagtgaaacc tatataatat taaatacaat atctgatggt gtattttcat
      781 ttttaccatt tatgttagct tactcagcag ctaaaatatt taaaatgaat acttatgttg
      841 ctgtagcaat agcaggagca atgctacatc ctaatttcat taatttaatt caacaaggct
      901 taactaaaat atcttttatc ggtattccga tgtcactaat ccagtataac ggaagtgtat
      961 ttccgatagt actaactatt tggtttgcat cgtatataga aaaaggagta gataaaataa
     1021 caccaaaggc acttaagata atattagtac ctgcattgac tattttattt gcagctccta
     1081 tagcattaat tattattgga ccaatagctc aaatgctagg aaactatata gccggtggag
     1141 caagtatcct atttgaaaga ggaggaatat ttgcagggtt aatttacgga ggaatttatt
     1201 cattcatggt agtaacagga ttacatcatg gtatggttcc tgtattagta gatggaataa
     1261 caagatatgg atttaactat ataagtcctg tgtcaggtag ttcaaatatg gctcaagcag
     1321 gatctgcatt tggagtatgg ttaaaagcaa aagataaaga tttgaaggct gtagcagcta
     1381 cagctaccat atcagcatta actggagtta ccgaacctgc aatatatggt gttaatttaa
     1441 gattaaagaa accgttttta tgcgctgcta taggtggtgc agcaggaggt ggatttgctg
     1501 catatttcca atgtaaagca tttgctatgg gaggtccatc gtttttaact cttcctatgt
     1561 ttataggaga aggtggacat gtaggattgg tagcaatagc atttacaata gcatttatag
     1621 tatctgcaat agctacctat atagtaggat ttgaagaaga ggtaacagca gattcacacg
     1681 ctaacttata ataaagagaa attatttaac atatcaaaaa ggagattaat tactatgaaa
     1741 atttatttaa ctaaagatta tgaagaaatg agccaagtgg cagcacaaat ggtgttaaag
     1801 tatatgtaca gcaatgataa taaaagaata aacctttcta taacagcagg tcaaacacca
     1861 aaaagaacat acgaaatatt aagtgaattt gttaagaata aaccttattt tgaaaatgta
     1921 cattattata actttgatga aataccaata aaaggcgaaa aagttggagt tactataaga
     1981 aatttaacta atatgtactt tagagaagct caaataccag aagaaagaat acatgtgtta
     2041 gatgaaaata attatcaagg ctttgataga aagatagaag ccgatggtgg aatagacatg
     2101 gtattaatgg gattaggttg ggatggacac ttctgtggaa atcttagtgg tacagtcaac
     2161 tcttttgatg aagagacaag agctgtttca acttatataa cagatgatat ggctaaacta
     2221 ttaacaaaat ctgtaggtgg aaatccagaa aaattatttg attactatgt gacatatgga
     2281 cctaaaacaa taatgcattg taaaaatata ataatgatag taaacggaaa acacaaagct
     2341 caaatattaa agcaaacact atttggacca ttagatttat tatgtccatc atctttattg
     2401 agattacatc ctaacttcac attaatagta gatgaagaag cagcatctga aataaaagat
     2461 ttaatataaa taagtaagga attaaaatta aaaatgaatt taggtgcaaa gtaatatttt
     2521 attttgcacc tttgctttaa taaaaaggag aataaaaatg tataatcata tgaaaaaagt
     2581 attccaagga ttagagggtg ggttattttc aagtgtagag aaagctgatg taggcgattc
     2641 ttatcaaaaa ttaggtgagc agggtgtaag tttaatggga tgggcagatc catttttccc
     2701 agattactgt atacctagac atatattaga tgcagctaca ttagcgatat caagtaatat
     2761 gtcaactcat tatacagcgc ctgtaggtaa tgacttatta aaaattgaga tagcagaaaa
     2821 attaaaagaa gtaaataatt tagatgttga ttttaaaaga aatatattaa taactcctgg
     2881 gtcagactca gggctttatt actcaatgtt accgtttata aatgaagggg atgaggttct
     2941 tataccaaca ccatgctatc caaataatat acaaaatact aaattaatgg gaggagttcc
     3001 tatatttgta gagttaaagg aatcagatgg atatcaaata gatataacag aatttgagaa
     3061 gagattaact aataagacga agttagtagt tcttactcat cctaataatc caacaactac
     3121 aatatttaat aaagaatctt tagaaaaatt agctaaattt attatagaca atgatttaat
     3181 attaatatgt gatcaagcat ttgaagattt tacttttgaa aatgaattaa taacaccagc
     3241 ttcattagaa ggtatgtttg aaagaacagt aacaatattt tcaacatcaa aaggtatggg
     3301 attaagtgga tttagagttg catatatggt atgcagcgat aaattaatgg acaaatacta
     3361 tggagcagca gtgacagtat taggtgctac taatacagta gctcaaatgt caacgattga
     3421 agcatttaaa gatagaagct ttatggagga ttttgaaaga gtttttgata aaagaaggca
     3481 agaagcatat aagataatca atgaaatacc taatgtatct atgcagatgc ctgagtccgg
     3541 atttttaggt tggataaatg tatcaaagct tggaacatca tcagaaatac aaaagtatct
     3601 agttgacgag gctaaagttt gtattaatga tggaattaat tatggtccag gaggagaagg
     3661 gcatttgaga ataattttag gaagctataa agacgatagt aaggtaattg gtgcattaaa
     3721 tagaataaaa gatgctttaa ttaaaaagca acaataaata aaaaataatt ggagtggagt
     3781 atgttatcaa tatttaagag taaaaaaaat gacaacaagc ttaaggcatt tgcatcaggg
     3841 aaagtaattc ctatagaaga tgttgatgat aatgtttttt catctaaaat gttaggtgat
     3901 ggaatcgcta tttatccaac taatgaatat gttgtagccc cttgtgatgc agaagtaaat
     3961 ataataatga aagatactaa acatgcagtt ggaattaaat tatttaatgg tatggaaatc
     4021 ttatttcatg ttggaataga tactgtatct atgaatggag aaggttttga gatatttgtt
     4081 tcaccaggtg acaagataaa aagaggtgat aaattaatat cttttaatag taaattaata
     4141 aaagaagaag ggttacaaga tgtagttata atggtagtta ctaattcaga acagtataaa
     4201 aatataaaat atcatattgg actggaggca gtaatcgatg atactattat tgcagaaatt
     4261 taaaaacagt tatttaagta aatacttaga taatttagat atagttaaaa ttaaatcctt
     4321 aaaatcaaat tatttaattt ttgtgtaatt ttaactataa agccgattaa taatataaag
     4381 tatactaaat aatatggtta ttatgattgt tactgacaaa gcctaagtag atataacaat
     4441 ttgctctaat tgagtattgc tatatctact tgtttttata tttaaaataa aagagtctgc
     4501 attgaaaaga taattctgat gagagtaaat agggtattta ataatagttt aattctgact
     4561 tatcaagatg aacctattca tatacctaaa acatctttaa caccttctaa attcatacaa
     4621 atagctgtat aggctgcctt attgattatt tttccgtcaa tttttacttt gtagtgaaca
     4681 gcatatataa atattatcga atagattgta tcaagagctc tattttgcta ttcattagct
     4741 aaagatagta ctctgtcagt tatttttgaa actaatgcat gagatatatc aattccgtaa
     4801 atattattta aatgtatgat atatatcgcg agtcgacatt ccttttgagt acatgccaat
     4861 tacttggttc tctattccag aaatttcatt ttcgtaattt tgaataaccc taggctggaa
     4921 atcatcccta gggatattta attttacctc tccaaaatct gatttaacat tcttagctct
     4981 atatccattt cttgaatttg atgttgcttt actttggtta tcatatctct cgtacattaa
     5041 atgatcttca atctctgact ctaacatttt gtgaattgtg cttgcgaata aatcttttaa
     5101 catctcttgg atgtctttag tattttttac atcatactct tgaactaagt gttttaatat
     5161 ttaatttttg ttgtacataa aaaatgtgta cctcctattt tggtaattag atttaatatc
     5221 ttgactttta ggagaataca cattttattt tacagaccct cttttctaga aaagttttta
     5281 tgaaaattgt gatataaatt attaataaaa aataatttta tatttatttt attatgtaat
     5341 ttagttttat taaaaatttt ttattattgg atatagatta tctattataa attttatctt
     5401 taagtttatt ctcctaaaat actatataat taaatcctgt aaattatctt caaagctttc
     5461 taggtaatca caaaataatc taaattcttc tatggtttta atttcttgta aatttctcaa
     5521 atctatcatt atattactat atttatgaaa cataaaattc atatcataca tttcacattt
     5581 aacaaattca ttttgataac tatatttata aggttcgtat tttgaaaaac tcgactcaaa
     5641 atattttatt ttagcataac ataatttgtg tatgttgaac aaaagtgcaa gaacagactc
     5701 cttaactgca aacttatgtg taaagtattt tatcgtgtgg tatttaccat gtttaaactc
     5761 ccaaattaaa tcctcattta aagtaagaga atattttttt ataaggttac gcgtatctag
     5821 tgttaaattt tgtattgaat gtattttcat aatttattct cctcataaat atttaataag
     5881 tattaaatta tagtgtttta ttattaattg ttcttaatta tattgtatgg taaattaaaa
     5941 aagtaataaa atagataatt aatatactag taatatatgc tataaataaa aacaatagct
     6001 aaaatagtaa tatatatgtt tttatgatat tttatgttta gggttatatt tgtaattatt
     6061 ttaagcttct aaaagtagat ttgatggata acgtataatt ttagaaggat atgcaatttg
     6121 tttgataaga acgtacatat gattaaatta aaaatattaa gtaccaaaaa gaagaaagat
     6181 agtttctccc tttggtactt aatattttgt atcctttaca ctaattttta atatttatta
     6241 atgatattat ttaatctaga gacttaaata aatttgccat ttctagcgca ttcatagcac
     6301 aatcataacc tttatttcca gcttttgtac ctgctctttc aatagcttgt tcaatatttt
     6361 ctgtagttac gattccaaat ataacaggta attcactgtc taaagatact ttggctatcc
     6421 ctttagagac ttcactacat acataatcat aatgagaagt agcccctctt ataacacagc
     6481 ctaaacagat tatagcatca tacttaccac ttttagccat tttttgagca acaagaggaa
     6541 tctcaaaagc tccaggtacc caaactattt ctatattttc tggagaaacg tcatgtctta
     6601 aaagacagtc ttcagctcct gataaaagtt ttgatgttat aaattcatta aaacgagaat
     6661 ttattatacc tatttttaaa tcttttccaa taagttttcc ttcatatatc atttttactt
     6721 cctccaattt tatttatgtt atagatttat atttataaat atctttaatt taattataaa
     6781 aaactactta gtagaaaaat atcatcatat aatcatttat ataatatcta aaagatgtcc
     6841 cattttatct tttttagttt ttaaatatag cttattaaag tcattaattt cttcattaat
     6901 agggattcta ttttcgattt ttattccata tttctctaat tgatttattt tatctgggtt
     6961 attacttaaa agatttatac tttttatgtt taaatttttt aatatttgag cagccatata
     7021 gaaatctctc atatcttctt caaatccaag cattaaattt gcttcaacag tatcgtaacc
     7081 ttcttcttga agtttataag ccttaatttt atttaaaaga ccaatacctc taccttcttg
     7141 cttcatataa attaaaactc cacttccatt ttccacaatt ttcttcatag aagattctag
     7201 ctgtaatcca caatcacatt ttagagagtg gaacacatct cctgttaaac attcagaatg
     7261 aagtctaact agagtatttt ctatatttat atttccataa gtaagggcaa tgtgttcttc
     7321 atttgaataa gtatctctat atcctatgat ttcaaaattt ccatattttg tcggaaggaa
     7381 agcactagat actttttcta tagtagtttc atttattttg cggtattcta taaggtcttt
     7441 tatagtgatg atttttaaat tatgcttttc tttgaaaatc attaaatcat caactcttgc
     7501 cattgtacca tcatctttca ttatttcaca gataagacca atctctttaa aacctgcaag
     7561 tctagcaagg tctactgagg cttctgtatg tccatccctg acaagaactc caccagtttt
     7621 tgctattaaa ggaaagatgt gaccaggcgt tttgaaatct ttacttgtag aattttcatc
     7681 acagaataat tttacagttt cagctctttc atatgcagat ataccagtta gagtatctgc
     7741 tccatctata gtaacagtaa aggctgtttg aaatgtatct gtattttctc taaccataag
     7801 aggtatatta agacttttaa attttttttc agtggcaggt agacaaatta gacctctacc
     7861 atatgtagcc ataaaattta ttgattcagg agtagccatt tcagctgcca tcaataaatc
     7921 tccttcattc tctctacttt catcatcaac tacgattacc attttcccat tttttatatc
     7981 ttcaatagct tcttcaatag tattaaacat gtaattcact cctttattat ttttaaaaac
     8041 catttttaaa taaaaaatct ttatctatat ttgatttatg gttactacta ttagaattta
     8101 attccttgta gttattagcc ataaaattat taacatactt tccaattaca tcgctttcta
     8161 aattaacgaa atctccaaca ttctttgtca agagaatagt gttaatttta gtatgaggta
     8221 taatagaaac cttaaatatt tcatcatcta aatatgatat agttaaactt acaccatcaa
     8281 tagcaacaga acctttgagt atcattgagg ataaaagttt tttatcaggt cgtatactta
     8341 ctaaaactgc attttcatct ttttcaaatt tgcagatagt tcctttacca tcaacatgac
     8401 ctgttactat atgaccacca aatcttgaag aaagactcat agctctttca agatttacct
     8461 tgtcatttgc atttaataaa cctaaatttg tggaacgaat tgtctccatc ataacatcgg
     8521 ctgtaaattc attttttccg aggtttgaaa cagttagaca aactccattt acggctatac
     8581 tatctccaag atttgtgcca tctaatattt tatttgatag tatggttact tttccactct
     8641 taccattagc agtaattttt ctaagtattc caacttcttc tactatgcca gtaaacatcc
     8701 taacctccta tatgaatgta ttaacaaaaa tttaatttaa aacatctgat tctataagaa
     8761 tatcgccatc tatcaaagtt acattattga ttgttaactg tgttgaatct gacaaatgat
     8821 ttattccttc tccagaaacg aatgtaggtg catctttacc acctataatc ttgggtgata
     8881 gaaataattt gactttatca actaacttat ttctaaagag actgtcattg agagtagcac
     8941 caccttcaac tagaacagaa tcaatgttta actctcctaa tttatacatt acaaactcca
     9001 aatctactaa gttgtttttt gaaggagaaa ttattgtttc aacattattt tcttttaaca
     9061 tagataattt tatactttct ttgcaacatg tgaaaactat agttttactg gttttatctt
     9121 taaccaaatt actattaagt ggcaacttta ggtgtgtatc tattactatt cttgtaggat
     9181 gagacacttt ttcttgattg agcctacaag ttagtaaagg attatcgttc aaaactgtat
     9241 ttatgccaac cattatactt tggtatttat ttctgtattt atgagttaga taccttgatg
     9301 attcattaga tatccatttt gattctagtg attttgtggc aattttacca tctagactta
     9361 ctgctgattt tacaatacaa agaggtcttt tgttttttat atgataaaaa aatgcctcat
     9421 ttaaatctct tgcttcatct tctaatattc ccacagtaac atcaatattg ttatctttta
     9481 atttttttac tccattacca caaacaagtg gatttgggtc taatgtagat attacaactc
     9541 tcttaatctt attttgtata attttatcta cacaaggagg cgttttccca taatgagaac
     9601 atggttctaa gtttacataa agagtagagt cttttagact ttgtttagca ctgtttatag
     9661 catttacttc agcatgatta gagccaaatt tctcatgata tcctttgcct attatattac
     9721 tatctttaac aattacacat ccaactaatg gatttggatt tacaaagcct tctccatttt
     9781 tagccaattc aatagctttt ttcatataat aaatatcttt ttctttttga ttcacaaaat
     9841 tcacaatatg tacacctcct gtttaattgg ataattttta aacaaaaaac cctgagaatt
     9901 aactcagggt ttagaataat ctacaataaa tgtttaataa atgtagaaca aaattgctct
     9961 acaaaaacac tcattaaata tcttcttcca tccagacttt actgtcggct ttggaattta
    10021 accaaatcaa ccaagtttta cattggctcg cgggctatac cgccgattgg gaatttcacc
    10081 ctaccccgaa gattaagtat taaatttata tttagaatgt atcataaatt attttacttt
    10141 gcaaactatt tttttaaaaa atatatgtta atatataata tagaatgtct ataaactttg
    10201 aaataccacg attgtgaata taaaaataaa aatttgaaca taatcaggaa agaagtctaa
    10261 ttaatttaaa ttaggagagt aatatatgaa taaaaaactt ttagaaatac tatcaaaata
    10321 ctatggatat acaagtttta gaaaaggtca ggaatctata ataaattcta tcttaagcga
    10381 aaaagatgtg ctagctatta tgccaacagg agggggaaaa tcaatatgtt atcaaattcc
    10441 agctttgatt ttagatggaa tgacaatagt aatttctcca cttatatcac ttatgaaaga
    10501 ccaagtagat gccttaaaga ctatgggaat tagtgctgct tttataaata gttcattaag
    10561 tagcaaagaa tttaatgaaa tattaaataa tattagaaaa aataattata aaatactcta
    10621 tattgctcca gagagattag atgcacaaga gtttattgag ctaataaata ataacaatgt
    10681 aagtcaagtt gcgatagatg aagcacattg tgtatctcaa tgggggcatg attttaggtt
    10741 gagttataga aggatttctg attttataaa aaatttgcct aaaagaccta tagttacagc
    10801 atttactgca acagcttcag aagaggtaag aactgatata ataaatttac tgtgtttaga
    10861 aaatccagat tattatataa ctggatttga tagagagaat ttatcaataa atatagtaaa
    10921 atcatctagt aaaaataagt atattttaga ttatattcaa aatcataaaa atgagtctgg
    10981 aattatatat gttgcaacta gaaaggaagt tgaaaatata tataatggtt tatctaagag
    11041 aaatatatct gtatcaaaat atcatgcagg tttatctaaa aatgaaagaa gtaaaaatca
    11101 agaagatttt ataaatgata atgtggatat aatggtagca acaaatgcat ttggaatggg
    11161 tattgataaa cctaatataa gatgggttat acattacaat atgcctcaaa gtatagaaaa
    11221 ctactatcaa gaaataggta gagctggtag ggatggagaa aaaagtgagt gtgtactttt
    11281 attttctcca ggagatgtac atatacaaaa atatttaatt gatattggag ttgaaaatcc
    11341 tgaaagaaaa ttatttcagc ataagaagct tcaatacatg attgacttag tttacagtaa
    11401 ttcatgctat agaaagacaa tattgagtta ttttggagaa aattatatag acaattgcaa
    11461 taattgtagc aattgtttag tagagggtga aatagtagat aaaactatag atgcacaaaa
    11521 agtcatttca tgtgtagcta gaatgaaaag aagttatggt gttactacta ttgtagatgt
    11581 gcttagaggt tctaagaata aaaagatttt acagcttgga ttaaatactt tgtctacata
    11641 taacattatg agagattatt ctagtgaaga cttaaagaat tttgtaaata cattggtttc
    11701 tcatggtttt ttagatttag ttgagactct aggcaatgga aatagaggta gttttcctac
    11761 tataagatta aatgagatgt ctatgaaagt tttaaaaggt gaagtgaaag tagagtttaa
    11821 agaaattgtt atgacaaaat cattggaagt agaggatgag ttatataatg ctttaagaga
    11881 acttagacat tcaattgcaa gtgaagaaag gatagctcca tatatggtat ttggagatgg
    11941 tacacttaga gccatgtcta gtagttatcc aattaataaa gaagaaatgc tagatatctc
    12001 tggagtagga gaaattaaat accaaaaata tggtagagat tttgaagcag taattaaaga
    12061 atatgtcgaa aaaataatat aaataaaaaa atagatgaaa aaaatgtcga ttcaaagaac
    12121 gttaatagtg atttcttaga ggttaataca gataaagttt tatatgaaaa actgttagtc
    12181 attagagaag aatatgcaac aaaggaaaaa ttacctgcat atatgatttt agccaataag
    12241 gctttgaaag aaataagtgg aagatatcca cttgatgaag aacaattaaa agatatttct
    12301 ggcataggtg gagtaaaatt tgaaaaatat ggagctagta ttttggcaga ggttaataaa
    12361 tatgtaaaag aaaataatat taatgttatt tgggagaaaa agggcaaaag gaagttaata
    12421 ttagatggag aaagtagaaa aaataatgaa atagcattag atttgctaaa tcaaggaaaa
    12481 gatatacaaa gtatcagtca agaaatagaa gtttcactgt caaccattat tggatatgtg
    12541 catgactatg taaaggatgg acatagtata tcatttgaat taggactaga aaatttttat
    12601 aatgaagata aaaagaagat gattttagaa gtttgcgaaa aagttggcta tgataattta
    12661 aataacataa aaagaaaact tccagattca ataaagtatg aaaatataag agctgtgata
    12721 cttgactctt atcttgaaaa cttaaaaaat aatattatag cagagtaatt tttaacttaa
    12781 taaaaaataa aatttgtatt attgtgttga actaataatt ttgctgtgtt atactgaatt
    12841 tgtaaaaata atgaaaaatt agagctaggg gcgctagaat tggctagctg agagataaag
    12901 ccgtaactta caaaccctaa taacctgatc aagataatgc ttgcgaaggg aagcttttta
    12961 atataatttt attatataaa taggcaaatt attcaatgtt aggagaaatt tgtctaagtg
    13021 tatatacgat tataagagtg ctttccaaac gaggaaaagc acttttttta ttttcaaaaa
    13081 ctataacttt aatcttggag gattgtaata tgaactatac aacacaaatg gatgctgcta
    13141 gaaaaggcat aataactaaa gaaatggaaa tcgtttctca aaaagaacag gtagatgtaa
    13201 atgaattaag agaattaata gcaaatggac aagttgttat accagctaat aaaaatcata
    13261 aatctttaag tgcagaaggt gtaggtaaaa atttaagaac aaaaataaat gtaaatctag
    13321 gaatttcaag agattgtaag gatatagaaa aagaacttga aaaagttaga gtagcaatag
    13381 acatgaaagc tgaagctata atggatttaa gtaattatgg caaaactaga gaatttagag
    13441 aaaaggttgt tgaaatgtca cctgcaatga taggttcagt acctatgtat gatgcagtag
    13501 gatatttgga aaaagaatta aaagatataa cagaagaaga gtttttaaat gtaataagac
    13561 aacatgctat tgatggagta gactttatta ctatacatgc aggtcttaca agaagtgttt
    13621 gccaaaaaat aaaaaatcat gagagattga ctcatatagt atctcgtgga ggttctttat
    13681 tgtttgcatg gatggaatta aataataagg aaaatcctat ttatactaat tttgataaaa
    13741 tattggatat atgtgaagaa tatgatgtta cattgagttt aggagatgct tgtagaccag
    13801 gttgtataaa agattctact gatggtgttc aaattcaaga acttgtagta ttaggtgaac
    13861 ttactaaaag agcatgggaa agaaatgtac aagtaatgat agaaggtcct ggacacatgg
    13921 ctattgatga aatagaagca aatgtagtat tagaaaagag attatgccat ggagcacctt
    13981 tttatgttct tggaccattg gttacagata tagcaccagg ttatgaccat ataacaagtg
    14041 caataggagg agctttagca tgtgctaaag gagtagattt tttatgttat gtaactccag
    14101 cagaacattt aagattgcct aatttagatg atatgaaaga gggtataata gctgcaaaga
    14161 tagctgctca tgcaggagat atagctaaaa atgttaaagg tgctcgtgaa tgggataata
    14221 agatgagtaa agctagagct gatttagact ggtgtgagat gtttagactt gcaatagacc
    14281 ctgaaaaagc taagagatac agagatgaat caactcctac tcatgaggat agttgtacta
    14341 tgtgtggaaa aatgtgctca atgagaacag ttaagaaaat attaaacaat gaggaactta
    14401 atctaatata atttttggct agtatgactg gaataaaaat aagctgaaaa gaggaggtga
    14461 tttagtgaag gttaatggga aggaaattga atttgaaaaa gatttgactg ttatagattt
    14521 attaaataaa tataatttaa aaagtgatag agttgtagtt gaagtgaatt tagagataat
    14581 tgaagaatct aactacaata catatgtatt aaaagacgag gacattgtag agcttattag
    14641 ctttattgga ggtggttaaa ataaaaatat ttgtaaatga attattaaca gatgttgagg
    14701 aaaatacaac tgcttataaa gttagagata gctataacaa taaatgtgat gtattggtgt
    14761 taaatggata tccaattaaa acagatatga ccctttgtga aaatgataaa ttaacactta
    14821 tacaaaaagg agttaagcca tcacttgatg aattggaaag cttgttgatt gctagacata
    14881 ctccaaatat acataataaa ttaaaaaaag ggaaagttgc tatattggga ttggggggac
    14941 ttggttccaa tatagctatc tctttagcta gaataggagt gggagaactt ttacttatag
    15001 attatgatgt tgtagaacca tctaatttaa atagacagca gtattttata gatgatatag
    15061 gaaaactaaa aactgatgcc atgatagaaa atataaaaaa aataaatcca tttataaaat
    15121 taaataaacg agatattttt ttaaacaaga acaatatgga tactattaag gattcagatt
    15181 taataattga ggcctttgat gatgcttcat gtaaagcaca ggtatgtaat tatgtattaa
    15241 taaatttaaa agataaatat ttaatagcat catctggtat ggcaggttac tatgattcaa
    15301 atataataac tactaagaag ataaaagaca ggttttatat atgtggggat tttgtgaatg
    15361 aagctaaatt tggtgaaggg cttatggctc caagggttgc catctgcgca aatcatatgg
    15421 caaatttggc aacgcaaata cttatagata tgtaaatatt aaaattagat ataaaaaaga
    15481 ttgaatatta aaaaaattta acgtggaggg aaataatatg gataaattgg tacttggtgg
    15541 acatgaattt aatagcagat tattggttgg aacaggtaaa tatggttcaa ataatatatt
    15601 gcctgaggta ataaaagaaa gtggaagtga aataataaca atggcactta gaagagtgga
    15661 tttagacaat aaacaagaaa acatattaac gtatattcca aaagagatga caatacttcc
    15721 aaatacatca ggagctacta atgcagaaga agctgtaaga atagctagaa tatctagaaa
    15781 aatgggatgt ggagatttta taaaaataga agtaatatca gatactagat atttacttcc
    15841 tgataatgaa gaaactataa aagctacaaa gatacttgct gatgaggggt ttatagttct
    15901 tccatatatg acaccagacc tttatgctgg aagaagactt atagaagcta atgcagcggc
    15961 agttatgcca cttggagctc caattggttc aaatagaggt cttcaaatga aagaaatgat
    16021 aagaataatg atagatgagt tggatatacc aataatagta gatgcaggta ttggaaaacc
    16081 atctcaagct atggaggcta tggaaatggg agctgatgca gtacttgtca acactgctat
    16141 agcttcagca ggagaccctg tacaaatggc tagagcattt aaattagctg tagaaggtgg
    16201 aagagaagca tatattgcaa aaacaggaaa tgtgtcagaa tttgcaaatg catcttctcc
    16261 tttaacaggt tttttaggca atttatagaa agtggtgatt ggtgatgagt ttttatgatg
    16321 taatagaaaa atatagggat tttgattttg atggatattt aaataatgtt actgataatg
    16381 atgttttaag aagtttatca aaagacaagc ttgaagattt tgatatatta aatttgcttt
    16441 ctaaaactgc agtaaaacat ttagaagata tggcacaaaa agcacataaa ttaagtgttc
    16501 aatactttgg taaaacagta tgtttatata caccaatgta tatagcaaat tattgtgtta
    16561 atcaatgtgt ttattgtagc tataatataa agagtggaat aaaaagaaaa aaattaacta
    16621 tggatgaaat tagagaagag ggagaagcaa tttcaaaaga aggtttcaaa catctacttg
    16681 ttttgactgg agaaagtagt tttcactcaa gtgtagaata tataggtgag gctatagaaa
    16741 tattaagaga gaaatttccc tctataggta tagaagttta tccaatggaa gtagaagaat
    16801 ataagtacat tgtagataaa ggtgttgaag gattaacagt atatcaagaa acttatgacg
    16861 aggaaatata taagagagta catataaaag gcccaaaatc aaattataaa tttagactag
    16921 atgctcctga aagaggggca aaagcaggta tgaggacttt atcaataggt gcacttttag
    16981 ggctaaatga ttttagaaaa gaaacttttt ttacaatatt gcatgggaaa tacttaaaaa
    17041 cgaaatatcc tcatattgag ctttcatatt caacaccaag aatgagacct tttaaagggt
    17101 gttttgagga attggtagat ataagtgata ctgatttagt tcaagctatg gtatgtatga
    17161 gattatttga ccctcatgca gctataaata tatccactag agaaaattta gaaatgagaa
    17221 gtcatataat acctttagga gtaactaaat tgagtgcagg tgtatctact gatgtaggag
    17281 gtcattctca agatgaacat gatactgctc aatttaagat aaatgatgaa agtactgtta
    17341 aagatgtgga gaaaatgcta aactcaattg gttatcagca tgtgtttaaa gattgggaaa
    17401 gattttaaat gtatctgata acaaacagaa aattatgtag tgaggaacga tatttagaag
    17461 ttattaaaga gtctatattg agtggtgtag aaaatataat aataagagaa aaggatttag
    17521 aatatcaaga gctaagaaaa ttatatatga aaataaaaac taaaatcaat tgtatagatt
    17581 ttcaagagca aatatcagat gaaagtttga aaactaatat aaatcaaaaa gagtgtagaa
    17641 ataaattcaa ggttaatttt ataataaata gtaacattga attttttgaa aaagtggatt
    17701 gtcaaggtat ccatcttcct tttaaattat tcttgaattt aattgaaaat aagtataatt
    17761 ttaatgaaaa taaaatacta ggattatctt tacataaagt agaggaagta gattatttag
    17821 aaaaattaat aagaaatcaa aatataaaaa tagattacat aacattatca catatatatg
    17881 aaactaaatg taaagaagga ttaaatccaa aaggaattga gcttttaaaa gaagctaaaa
    17941 agattactga tattaaaata attgcacttg ggggaatttt accatctaat gtcaaggaaa
    18001 cattaaaata ctgtgatgat tttgctataa tgtcaactat aatgaggtct aaagatatta
    18061 aaaaaaccat atcaaattat aatgaaaagt tgaattagta aatatagtat attgaatttt
    18121 taacttaaat aaaaataaaa aagttatctt ttaaatttta aaaggtagct tttttatttt
    18181 atatctttgc taataaaaaa ttgtaaaaag ggaaaacttt agtcagagag attaaacaat
    18241 atcctagaaa gatttaaaat ttagtaaagt atggaggaca ttataatgac tgacagtaaa
    18301 aagaaacgat ttattatacc acacactttt acaataatat ttttactaat agtcttgatg
    18361 gcaatattga cttggatagt accaagtggt gaatttagta gagaagatgt agaaggtaga
    18421 atggtagttg taccagggac ttatcaaagt gtagaaagta atcctcaagg atttgcagat
    18481 gtttttaaag caccaataga aggctttatc gattcagctg aagttgtagg ttttgtttta
    18541 atagttggag gtgcttttgg tattgtaaat aggactggag ctatagaagc aggaatagct
    18601 tcggttatct ctaagtttaa gggaaaagaa cttcttataa ttccaatatc aatgatttta
    18661 tttggacttg gaggtacaac atttgggatg gcagaagaga cattaccatt ttatatgata
    18721 tttgttccac tcatgacatc cttgggatat gattctctaa cagcaatagc aattgtattt
    18781 ataggagcag cagcaggagc cgccgcttca acaataaatc cattttcagt tggtattgca
    18841 caggcactag ctcaacttgc tcctggttca ggagtaactt acagagtagt tatttttata
    18901 gcatatatac taataagtat agcatttgtt atgtactatg ctaagaaggt aaaggaaaat
    18961 cctgaaagtt caatagtata tgaaatagat aaaaataata aatcaatact taatcaaact
    19021 tcaacagaaa taaaagaatt tacttttaaa gaagtatctg ttcttgctat atttggaata
    19081 gggatggcaa taatgatttg gggtgtttta agtcaaggat ggtacattcc agaaatatca
    19141 atgtgttttg ctgcaatagg tgtgctttct ggattggttg gtagattatc tcaaattgaa
    19201 atctcagaaa gttttataga tggagcaaaa gatttagcat ctgcagctct tgctatagct
    19261 ttggctcgtg gaatcgtaat aattgctcaa aatggattta taatagatac tatattaaat
    19321 tccgcagcag cctttctagg tgggcttcca aaggttatat ttgtatattt atcatttttc
    19381 ttggaagctg cattggcatt tttaattcca tcatcttcag gtcttgcttc acttacagta
    19441 cctgtacttg ctcctcttgg tgatttggtt aatatatcgg ctcaagtgat agtaaccgct
    19501 tatcaatttg gtgtgggtct tacaaacttt ataactccaa cttcaggagt actgatggga
    19561 gcacttgcag tagcccatat tccattttca aaatgggtaa gatttataat gcctatcttg
    19621 ttgattttga cagctgtatc tctagtcttt ttaacaatag gtatttatat agggttttaa
    19681 ttaagtgtag ttttatttaa gatatttagt aatggtataa aatgataata tgttttcaat
    19741 aaattgc
//
LOCUS       DAJMZY010000077        19633 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.077, whole genome shotgun sequence.
ACCESSION   DAJMZY010000077 DAJMZY010000000
VERSION     DAJMZY010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 19633)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19633)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19633
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.077"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            complement(<1..827)
                     /locus_tag="OE968_002619"
     CDS             complement(<1..827)
                     /locus_tag="OE968_002619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HCP7219891.1"
                     /translation="MKDKNTYFNRKGQENFIDIFLKDDIKKGANFKRHWHEHLQIYYF
                     IDGIAYLECGLDNFKVVPGNIVIANSNELHYLESLSDNLKFYSIRIEPTFLFSNQVDL
                     LQTKYLAPLALNHIVFNNLIQNDSLILKCITTILDEYHNKEVGYELSIKANIYQLIVL
                     LLRSHIDKIYSEDEFIKRKYSLEKFECIFDLIEEKYMDKITLKELASRVNLSAHHFCR
                     TFKQITGKTTIDFINGIRLDKAIYYLKETDLNMTEIAMRCGFDSINYFSRLFKKNYN"
     gene            968..2395
                     /locus_tag="OE968_002620"
     CDS             968..2395
                     /locus_tag="OE968_002620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCP7219892.1"
                     /translation="MTNSFKKDDNRKKITVLFVVIAMTFMATLDSSIINVALPVLASK
                     LNVSLASIEWVIASYSIIICSTLLFFGRLGDIIAKSRVFQVGTILFTSASLLCGLSNS
                     LTLLIVCRFIQGIGASAYMANNHGIITELFPKESRGKALGILVTAVAIGNMVGPSVGG
                     FILSIFNWNVIFFINIPIGLIVIFLNTKFLPNSKKSSENMDKTGAILQFLGTTLFFSA
                     LISAQQTGLLNPYILIALLLSIIFIILFLILEKKHPQPLLDLEIFRNFKFSLNLICAL
                     TSFICIASSSILIPFYLQSTMKLPPIQAGLFMILSPLILAIFSPIFGNISDKIKSEKI
                     ILIGLLVMSFGFFLMSRLKESSALILFVIYISIISIGQAIFQPANNALIMSSCSRSKL
                     GVVGSINSLVRNLGQVIGITISTTLLYNFMSIKAGYRVNDYVINNDKIFVFGMRNVYI
                     IVTLVCLIGAILIGFYLFKYNKNEQ"
     gene            complement(2591..5185)
                     /gene="clpB"
                     /locus_tag="OE968_002621"
     CDS             complement(2591..5185)
                     /gene="clpB"
                     /locus_tag="OE968_002621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HCP7219893.1"
                     /translation="MDVEKMTLRVQKSLNEAYNEAVKNHNQQVDVIHLFSALINQEDG
                     LIPNIIEKMNISIDSLRNTVNFEIDKLPKVYGEGADSQGVSATRKINEVLIKAESISK
                     EFKDSYISVEHVMLAMMETESKSAVGKILKQYNINKNDFLNILSQVRGSQRVETQDPE
                     GTYDALARYGTNLVDLAKKNKLDPVIGRDEEIRRIIRILSRRTKNNPVLIGEPGVGKT
                     AIVEGLAERIVRGDVPEGLKDKIVFSLDMGALIAGAKYRGEFEERLKAVLKEVQSSDG
                     KIILFIDEIHTIVGAGKTEGSMDAGNLIKPMLARGELNCIGATTFDEYRKYIEKDKAL
                     ERRFQPVIAEEPTVEDTISILRGLKERFEIHHGVRIHDNAIVAAAKLSHRYIQDRFLP
                     DKAIDLIDEAGAMIRSEIDSLPTELDVVRRKLFTLETEREALLKENDDKSKSRLDDIQ
                     KEIAELKSKNDEMTAKYEKEKSQILDIKNLKAQLDEAKGKAEKYEREYDFNKAAEVKY
                     GEIPKLEEQIKQYEENMNDGSENSLLKEEVTEEEISSIVSKWTGIPVTKLVEGEREKL
                     LKLEDELHKRVIGQDEAVTAVSNAVIRARAGLKDERKPIGSFIFLGPTGVGKTELAKT
                     LARNLFDSEDNIIRIDMSEYMEKHAVSRLVGPPPGYVGYEEGGQLTEAVRRAPYSVIL
                     FDEIEKAHEDVFNMFLQILDDGRLTDNKGKTVDFKNTLIIMTSNIGSNYLLEAGGNIT
                     ETTNNLVMNEMKHRFKPEFLNRVDDIIMFKPLDQENIKKIIDIFMKDLKNRLKEKDIT
                     IEVTNSAKDVMVREGYDPVYGARPLKRYIGNTLETIIAKKLIAGDVYNGCTIVIDGKD
                     ENIEVLVK"
     gene            complement(5222..5818)
                     /locus_tag="OE968_002622"
     CDS             complement(5222..5818)
                     /locus_tag="OE968_002622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219894.1"
                     /translation="MSLKLDRNVLQWFDYVFENEKTSLRHYNFNCTLKEISSTSLNKV
                     AFILEKNNSKYWKLYFEIPAEVTLKLKQNIHPLFREYIYEQISLYNNNQIYNFVNSNI
                     LKVFNNIAIYQYNILENLYTIDFKKSFIDKCQYLLIGEKRLIDEDLYLIAKSKEVFDF
                     FNSDGTFNLTLSFDIQKNENLLDSLLELRKSIIINERI"
     gene            complement(5835..6239)
                     /locus_tag="OE968_002623"
     CDS             complement(5835..6239)
                     /locus_tag="OE968_002623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication/maintenance protein RepL"
                     /protein_id="HCP7219895.1"
                     /translation="MDKTLKKDLNQEYTESKSLVMNKSKYMNVCFKNYIKVVEGMYTK
                     RDLIPLKLINSMDKNNKIRKTLYELSCEFEYPKTSLSSLFTELKKMDFLQRVKNGEYM
                     INPHIAYKGSRADKESLLAEYNQIKRPNKVSK"
     gene            6606..6980
                     /locus_tag="OE968_002624"
     CDS             6606..6980
                     /locus_tag="OE968_002624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCP7219896.1"
                     /translation="MNIVISNSSGKPIYEQITTQIKSMIISGELPEGSALPSMRLLAK
                     ELRISVITTKRAYSDLERDGFIETVTGKGSFVSSKNMDFVKEEQFRLIEEYLQKAVDT
                     AKSSDITYDELKDILFLLYKGE"
     gene            6977..7840
                     /locus_tag="OE968_002625"
     CDS             6977..7840
                     /locus_tag="OE968_002625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCP7219897.1"
                     /translation="MISMDAITIKNLNKTYKDFSLQDISFSVPKGSVMGFVGENGAGK
                     TTTLKAILNLISYDSGNIEIFGLDSKKNEKEIKEQIGVVFEGSNFHENLNTDHVSKIM
                     SKIYKNWNDTLFKDYLKKLRVPDNKLIKEFSKGNKMKLSIAVALSHKPKLLILDEATS
                     SLDPIVREEILDIFLDFIQDEEHSIILSSHITSDLDKIADYITFIHKGKIVFSENKDE
                     LIDTMGVLKCKPSDFDNLSREDYSYYRKSQFGYEVLLKDKHRFISRHPNCIVDNTSIE
                     EIMLFYVRGDK"
     gene            7840..8478
                     /locus_tag="OE968_002626"
     CDS             7840..8478
                     /locus_tag="OE968_002626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 transporter permease"
                     /protein_id="HCP7219898.1"
                     /translation="MKGLILKDLLNLKGNIKFILLFIIMFGFMSSLGDGNVNNFIGVI
                     IVLCTTMIVSTFSYDDLNKWDSYVLTMPINRNDIVLSKYLTMLIFSFIGVLVSLIVSV
                     TIGYFKNTLILNETLLINALILSISVCFGSLILPLIYKFGTERARLLMILCFLVPTLA
                     LLVFKSILENISSPISIEIILNTLVYSLPFVAILLFVISYFISSKIYSKKEV"
     gene            8970..9383
                     /locus_tag="OE968_002627"
     CDS             8970..9383
                     /locus_tag="OE968_002627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCP7219899.1"
                     /translation="MELEITEKIEKQDEDTIFQGLLKYNLARLEDKNPVDLGIYIRDK
                     AGKIVAGFIGVTHGNWLSIKYLWVSEKLRYKGTGSQLLYKAEKIAKERGCKYVFLDTF
                     SFQAPKFYEKFGYHKVFSLENYPLTGKRYYFRKIL"
     gene            9574..10791
                     /locus_tag="OE968_002628"
     CDS             9574..10791
                     /locus_tag="OE968_002628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallo-hydrolase"
                     /protein_id="HCP7219900.1"
                     /translation="MLGKKCMDYLQTLGKISSTTNGLTRLILTQEHKKSIDLISSWME
                     GLNLDIEIDDIGNVIGTYKSSFPNAPTLVVASHQDSVKCGGIFDGMLGIIVPLVGLEE
                     AKHNNRSYPFNIKLIAFAEEEGTRFETSLMGSKVFAGTFKEELLKSVDENGITLEEAV
                     TKFGFNTKNLTNLHPRKDVDAYLEFHIEQGPVLENESLPAGIVSSITGFKSFKISVNG
                     KSGHAGTLPMNMRLDAGCCACECVLAIEKVAKTTADLVATVGKMNFYPSSSNVVPERA
                     EFTLDVRSCSQEILDNSVEKIFNEISHICENRKLNYTSELAFENVPVPCSNKITKIIE
                     KSFIDLNLNPFYIYSGAGHDAQEMDNITDIGMVFIRCAGGVSHNPNESVSVDDLDTAV
                     KIFLKILDNLDLK"
     gene            10953..11651
                     /locus_tag="OE968_002629"
     CDS             10953..11651
                     /locus_tag="OE968_002629"
                     /EC_number="5.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid racemase"
                     /protein_id="HCP7219901.1"
                     /translation="MNEKLIGILAGMGPRSTAPFVDLIIDECQSQYGAKYDDEFPKMM
                     IYSLPTPFYIDRPINHELMKETIIDGLQKLESTGVNFIAMPCNSAHIYFKELKESINI
                     PILNIVEETVKKLPTISQKVTLFSTSSTFESTIYQNGIIHNGHEFIFKDEWQIKLNNL
                     IQNIKMDKENPHNIDIWNKLIEDVKNESIENIVIACTDLNVVLEKSYPSINIVDSSKC
                     LAESVVNKYLKLVK"
     gene            complement(11871..12488)
                     /locus_tag="OE968_002630"
     CDS             complement(11871..12488)
                     /locus_tag="OE968_002630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4878 domain-containing protein"
                     /protein_id="HCP7219902.1"
                     /translation="MKKIILALTTFLLAISLTACSSAKPEDTIDSFFNSAKKFDFEGM
                     NKVMENNDEKYKDILKELDTKDPNAQYVLDYLKQNASKITYTIKDSEVKGDKATIKVE
                     CKFIDSTPLLQEIVAEAFTKMIGMSFSGQDLTDEKTTEMLVSIMKEKQKSVKETYVTK
                     NVEFECSKKDNKWIISSVNDAVADVLLSNLVTAGQEFSNSMNTLE"
     gene            complement(12615..13637)
                     /gene="argF"
                     /locus_tag="OE968_002631"
     CDS             complement(12615..13637)
                     /gene="argF"
                     /locus_tag="OE968_002631"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HCP7219903.1"
                     /translation="MNNISLKGKSFLTLKDFTKEEIRYLLTLSSYLKTKKKVGIKGDL
                     LQGKNIALLFEKTSTRTRCSFEVAAHDEGAHVTYLGPNDCHMGKKESVSDTAKVLGRF
                     YDGIEFRGFKQETVESLAKYSGVPVWNGLTDEYHPTQILADFLTVIENVDKDLNKVKF
                     VYVGDARNNMGNSLMIGCAKMGIHFVALAPKELWPNEELVKEMKEIAKKSKGDIMLTE
                     NIDDVKGADVIYTDVWVSMGEEEQYEARINQLKDYQVNMDMIKKTENENVIFLHCLPA
                     FHDLETKVAQEIYEKFGLSELEVTNEVFNSKYSKVFEEAENRMHTIKAVMVSTMTDVN
                     MNNNLI"
     gene            complement(13746..14933)
                     /locus_tag="OE968_002632"
     CDS             complement(13746..14933)
                     /locus_tag="OE968_002632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate aminotransferase family protein"
                     /protein_id="HCP7219904.1"
                     /translation="MNNDNTISKWNEYFIDTYNQPNFVIDYGEGSCFFDTNGNKYIDF
                     TSGYGVSSLGYSNSNLKNALKEQVDKLLHTSNLYFNEPVLYSGEKIINSSGMAKVYFC
                     NSGTEANETAFKIARKYSSDKYGNGRGTIISLKDSFHGRTMMSLMATGMDKYHKYFYP
                     LPEGFKYVERNNIEDLKNNLDSTVCAIILEAIQGEGGVNVLEKDYVLEIVKICQEKDI
                     VVIFDEVQCGIGRTGKLFGYEYFDVKPDIVTVAKGLGAGIPVGGVLVNKKLSKVLGKG
                     DQGTTFGGNLLAMVAASVVLDEISKDGFYNEVLEKGNYIRKSIESFNNKVVLKTKGIG
                     LMIGIETNIESSIIEEKARKKGLLILTAGKNVLRFLPPLTISYKEIDEALEILKDILL
                     EIN"
     gene            complement(14963..15823)
                     /gene="argB"
                     /locus_tag="OE968_002633"
     CDS             complement(14963..15823)
                     /gene="argB"
                     /locus_tag="OE968_002633"
                     /EC_number="2.7.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylglutamate kinase"
                     /protein_id="HCP7219905.1"
                     /translation="MINIEKANTLIEALPYIEKHQGKTIVVKYGGSAMKKDGLKESVM
                     EDLVLMSYVGINIVLVHGGGAEINKMLAKVDIESKFVNGLRYTDEETMEIVKMVLAGK
                     VNKDLVNKIHTKGGKAVGLCGIDNNMILCDPYKNYELGFVGEIKKVNVELIESCLKSG
                     YISVIATIGVGDDGETYNINGDTAASAIAKELNADKLILLTDVPGLLREPDEEKSLIT
                     EVILEDVDKLFEEGIITGGMIPKIEGCVDALNNGVNRVHILDGRVPHSIITELFTDSG
                     IGTLIRKENE"
     gene            complement(15838..17055)
                     /gene="argJ"
                     /locus_tag="OE968_002634"
     CDS             complement(15838..17055)
                     /gene="argJ"
                     /locus_tag="OE968_002634"
                     /EC_number="2.3.1.1"
                     /EC_number="2.3.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate
                     N-acetyltransferase/amino-acid acetyltransferase ArgJ"
                     /protein_id="HCP7219906.1"
                     /translation="MEIIKGGVTVSEGFFASGIHCGLRKNKEKRDLALVYSDVLCDAA
                     AVVTQNKVKGNPVYVTQEHIKNGKAQAIIVNSANANTFNGKEGLINAYKMAKFTSDKL
                     NIKESDVLVASTGVIGKPLNIDLIEENMDELVNNLSKQGHIGAREAIMTTDIIKKEIA
                     VAIMYGDKKITIGGMAKGSGMIHPNMATTLGFITTDANIDGVLLKEALKIAVDKSFNR
                     VSVDGDTSTNDMVMILANGKAKNDRINKKDEHYQVFLSALTYVCIELAKLVAKDGEGC
                     TKLIECYINGALSEAHAVKLAKTVISSSLVKTAVFGADANWGRILCALGYAGEEIDME
                     KVDIIFESMKGYIEVCKNGNGLDFNEEKAKKILEDDEISILVDLNMGNARGNAWGCDL
                     SYDYVRINGSYRN"
     gene            complement(17096..18130)
                     /locus_tag="OE968_002635"
     CDS             complement(17096..18130)
                     /locus_tag="OE968_002635"
                     /EC_number="1.2.1.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyl-gamma-glutamyl-phosphate reductase"
                     /protein_id="HCP7219907.1"
                     /translation="MNKIKVGIIGATGYVGAELIRLLMNHDKVEVTAIGSNSYVGKDI
                     VDIYPSIGYKNNMICIENEKVIDMCDVVFTALPHGVSEKFVIKAIKSKKKVIDLGADF
                     RIKDEEVYSKWYGVSFIDKILHKKAVYGLSEIYKEDIKDADIIANPGCYPTSISLPLM
                     PLLSSKLIKNNNIIIDSKSGLTGAGRELSISSHFTEVNENITAYKIGKHRHTPEIEQN
                     LSESCKEKVSVVFTPNLIPVNRGILSTIYCTKEDNISINDIHRKLTDYYEFKEFIEIL
                     PLDKIASLKNVRFSNKCVISLHENGDTLIICSAIDNMIKGAAGQAIQNMNIIFGIEEN
                     TGLKNIAPSF"
     misc_binding    complement(18384..18597)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(18815..19582)
                     /locus_tag="OE968_002636"
     CDS             complement(18815..19582)
                     /locus_tag="OE968_002636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YoaP domain-containing protein"
                     /protein_id="HCP7219908.1"
                     /translation="MQIIDININNIDNEHICCSISEKKGENCVFSKKAWMKNNFDKGL
                     VFKRFDVRGKAFIEYIPAENAWCPITADNYIFINCFWISGKFKGQGYSNLLLQECVDD
                     AKSKGKYGLVVLSSSKKMPFLSDAKYLKYKDFCLADTSEPNYELLYFPFTDNAPIPCF
                     KNCVKQRKLNENGIVLYYSNQCPHTEKYAPILKKIANSRGIDVNLIKFETAKEAQNAP
                     APFTTYSLFFNGEFVTNEILSEKKIEKFLDTNIKKFN"
BASE COUNT         6562 a         3091 c         2199 g         7781 t
ORIGIN      
        1 atattataat tctttttaaa taagcgacta aaataattta tgctatcaaa gccacatctc
       61 atagcaattt ctgtcatatt taaatctgtt tcctttaaat aatatatagc tttatcaagc
      121 ctgattccat ttataaaatc gattgtagtc ttacctgtta tttgcttaaa tgttctacaa
      181 aagtgatgtg cactcaagtt cacacgacta gcaagttctt ttaatgtaat tttatccata
      241 tatttttctt ctatcaaatc aaagatacat tcaaattttt ctaaagaata ctttcttttt
      301 ataaattcat cttcagaata tattttatca atatgacttc ttaataagag tactattaat
      361 tgatagatat tagcttttat agataactca tatccaactt ctttattgtg atattcatca
      421 agtatagttg taatacattt taaaatcaga gaatcatttt gaattaaatt attaaataca
      481 atatgattta aagccaatgg tgctaagtac ttggtttgta acaaatcaac ttgattacta
      541 aaaaggaatg tgggttcaat acgaatacta tagaatttta aattatctga taagctttct
      601 aaataatgta attcattact gtttgctatt acaatatttc caggcactac cttaaaatta
      661 tccaatccac attcaagata tgctatacca tcaataaaat aatatatttg tagatgctca
      721 tgccaatgtc ttttaaagtt tgctcctttt ttaatgtcat cctttaaaaa aatatctata
      781 aagttttctt gacctttcct gttaaaatat gtatttttat ccttcattat tcccccctca
      841 tcaaaatagt gctaattata agcaatatag ttattgtatt cattatttca tatcgctatt
      901 atataaaatg taactatcat tgtaaacatt aacataatgc agtcattata ataaggaggt
      961 aataaaaatg acaaactctt ttaaaaaaga tgataataga aaaaaaatca cagttttatt
     1021 tgtagtcatt gccatgactt ttatggcaac attagattct agtattataa atgttgctct
     1081 cccagttctt gcaagcaaac taaatgtatc tctagcatct attgaatggg taatagcaag
     1141 ttactcaatt attatttgtt caacactatt attttttgga agacttggag atattattgc
     1201 taaatcaaga gtatttcaag taggtactat tctctttaca tcagcttcat tactatgtgg
     1261 attaagtaat tctttaactt tacttatagt ttgccgcttt attcaaggaa taggcgcttc
     1321 tgcctacatg gcaaacaatc atggaattat cacagaacta tttccaaaag aaagcagagg
     1381 aaaagcccta gggattttag ttactgcagt tgctattgga aatatggttg gaccatctgt
     1441 gggaggattt attttgtcaa tatttaattg gaatgttata ttttttataa atattccaat
     1501 cggtcttatt gtaatctttt taaatacaaa atttcttcct aatagtaaaa aatcttcaga
     1561 aaatatggat aaaactggtg ctatacttca atttttagga acaacattat tttttagtgc
     1621 tctaattagt gctcaacaaa caggattact aaatccatat atattaattg cactattatt
     1681 atcaattatt tttattatat tatttttgat attagaaaaa aaacatcctc aaccgcttct
     1741 tgaccttgaa atttttagaa attttaaatt ttcattgaat ttaatttgtg ctcttacatc
     1801 attcatttgt attgcatcat caagtatttt aattccattt tatttacaaa gtactatgaa
     1861 acttccccct attcaagcag gtttatttat gatactatca cctttgattt tagccatttt
     1921 ttcacctata tttgggaata tatcagataa aattaagtca gaaaaaatta ttttaattgg
     1981 tcttctcgtt atgagttttg gattctttct aatgtcaaga ttgaaagaaa gttctgccct
     2041 tattttattt gtaatttata tatcgataat atcaatagga caagctatat ttcaacctgc
     2101 taacaatgct ttgataatgt caagctgttc tagaagtaag ctaggagttg taggaagcat
     2161 aaattccctt gtaagaaatt taggacaagt tataggtatt actatttcta caacactttt
     2221 atataatttt atgagtatta aagctggata tagggtcaat gattatgtga ttaataatga
     2281 taaaatattt gtatttggaa tgagaaatgt ttatattatt gttacacttg tttgcttaat
     2341 aggtgcaata ttaattggct tttatttatt taaatataat aaaaatgaac aatagttttt
     2401 ataattatat tcaaattatg attatattat aagaaattta ctaaaatact tcctttgagt
     2461 taaatttaat ttggacatat tgacttaaaa atgttttatt aatttgataa aatatttctt
     2521 ttcctatagt ttataaataa aaatcagctg agcaaaatat ttagtatatt atgctcaact
     2581 gattctttta ttatttaact aaaacttcaa tattttcatc ttttccatct ataactatag
     2641 tacatccatt atacacatct ccagcaataa gtttctttgc aattatagtt tctaatgtat
     2701 ttcctatata tctcttaaga ggtcttgctc catatacagg gtcatatcct tctctcacca
     2761 taacatcttt tgctgaattt gtaacttcaa tagtaatatc tttttctttt aatctatttt
     2821 ttaaatcttt cataaatata tctataattt tcttgatatt ttcttggtct aaaggcttaa
     2881 acattataat atcatctact ctgtttaaaa actcaggttt aaatctatgc ttcatttcat
     2941 tcattactaa attgttagta gtctctgtta tatttcctcc tgcttctaat agataattac
     3001 ttcctatatt agaagtcatt attataagag tatttttaaa gtctactgtc ttacctttat
     3061 tatcagtaag tctaccatca tctaatatct gtaagaacat gttaaataca tcctcatgtg
     3121 ctttttctat ctcatcaaat agtattacag aataaggagc acgtctaact gcttctgtaa
     3181 gttgaccacc ctcttcatat cccacgtacc ctggaggagg tccaactagt cttgatacag
     3241 catgtttttc catgtattca gacatatcta ttcttattat attatcttca ctatcgaata
     3301 aatttctagc aagagttttt gcaagttcag ttttaccaac acctgtaggg cctaagaaaa
     3361 taaatgaacc aattggtttt ctttcatctt ttaatcctgc tcttgcacgt attactgcat
     3421 ttgaaactgc tgtaactgct tcatcttgtc caataactct tttatgaagt tcatcttcta
     3481 gtttaagtaa tttttctctt tctccttcaa ctagtttagt tactggtata cctgtccact
     3541 ttgatacaat gctagatatt tcttcttcag taacttcttc ttttaaaaga gaattttcag
     3601 aaccatcatt catattttct tcgtactgct ttatttgttc ttctaactta ggtatttcac
     3661 catatttaac ctctgctgct ttgttgaaat catattctct ttcatacttt tcagctttac
     3721 ctttagcttc gtctaattga gcctttaagt ttttaatatc taatatttga ctcttttctt
     3781 tttcatattt tgctgtcatt tcatcatttt tagattttaa ctctgctatt tctttttgaa
     3841 tatcatccaa tcttgattta cttttatcat cattttcttt aagtaatgct tctctttcag
     3901 tttctaatgt aaataacttt cttctaacaa catctaattc tgttggcaat gaatctattt
     3961 cactacgaat catagctcca gcttcatcaa ttaaatcaat tgctttatct ggtaaaaatc
     4021 tatcttgtat atatctatga gaaagttttg ctgctgctac aatagcatta tcatgtattc
     4081 ttactccatg atgtatttca aatctttctt ttaaacctct aagtatagat attgtatctt
     4141 caacagtagg ttcttctgca attacaggct gaaaacgtct ttcaagagcc ttatcttttt
     4201 ctatatactt tctatattca tcaaaagtag ttgcaccaat acagttcaat tcacctcttg
     4261 caagcatagg tttaataaga ttacctgcat ccattgaacc ttctgtttta ccagctccaa
     4321 caatagtatg aatctcatct ataaacagta taatttttcc atcagaactt tgaacttctt
     4381 ttaaaactgc ctttaatctt tcttcaaatt cacctctata ttttgcacca gcaattaaag
     4441 ctcccatatc aagtgagaat acaatcttat cttttaaacc ttctgggaca tctcctctta
     4501 ctattctctc tgctaaccct tctacaattg cagttttacc tacacctggc tcaccaatca
     4561 atacaggatt attttttgtt cttcttgata aaattcttat aatccttctt atttcttcat
     4621 ctctcccaat tacagggtct aatttatttt tcttggctaa atctactaag tttgttccat
     4681 atctagcaag tgcatcatat gtgccttctg ggtcttgtgt ttctactctt tgactacctc
     4741 tcacttgtga taaaatattt aaaaagtcat tcttatttat attatattgt tttaatattt
     4801 taccaacagc tgattttgat tctgtttcca tcattgcaag cataacatgt tctacactta
     4861 tatatgaatc tttaaattct ttagaaatac tctctgcctt tataagcacc tcatttattt
     4921 ttctagtagc tgatactcct tgtgagtcag caccttctcc atatactttt ggaagcttat
     4981 caatttcaaa gtttacagta tttctcaaag aatcaattga tatattcatt ttttcgatta
     5041 tatttggtat caatccatcc tcttgattaa taagtgctga gaaaagatga attacatcta
     5101 cttgttggtt atgatttttt actgcttcgt tataagcctc atttaaactt ttttgaactc
     5161 ttaaagtcat tttttctacg tccatataaa tccctccatt ttaatattat atccaaataa
     5221 attaaattct ctcatttata attattgatt ttctaagctc taaaagacta tcaagtaaat
     5281 tctcgttttt ttgtatatcg aaactcaatg ttaaattaaa tgttccatct gaattaaaaa
     5341 aatcgaatac ttcttttgat tttgctatta aatacaagtc ttcatctata agtctttttt
     5401 cacctattaa taaatactga catttatcta taaaactctt tttaaaatca atagtgtata
     5461 gattttctaa aatattatat tgataaatag caatattatt aaacactttt aatatgtttg
     5521 aatttacaaa attgtaaatt tgattattgt tatacagtga tatttgttcg tatatatatt
     5581 ccctaaataa aggatgaatg ttttgcttaa gttttaaagt aacttcagct ggtatttcaa
     5641 aataaagctt ccagtactta gagttatttt tttctaaaat aaaagctact ttgttcaaac
     5701 tggtagaact aatctccttt agtgtacaat taaaattata gtgtctcaaa ctagtttttt
     5761 cattctcaaa tacatagtca aaccactgta gaacatttct atcaagtttt aaactcatat
     5821 aaaaaccttc ttccttattt actaacctta ttaggtcttt ttatctgatt atattctgct
     5881 aataaacttt ctttatcagc tctactacct ttatatgcta tatgtggatt tatcatatac
     5941 tcaccatttt tcactctttg taaaaaatcc atttttttca gctccgtaaa caatgaagat
     6001 aaagaagttt ttggatattc aaattcacaa gataattcat ataatgtttt tctaatctta
     6061 ttatttttat ccatagagtt tattaatttt aatggaatta aatccctctt agtatacatt
     6121 ccttctacta ctttaatata attcttaaaa caaacattca tatacttact tttattcata
     6181 actaaacttt tgctctctgt atattcctga tttaaatcct tttttaatgt cttatccaaa
     6241 ttaaatatct cttctcactc tccttatctc taattgataa tataaatata ttacaaaaaa
     6301 atatgtatgt caaaactgaa aatgcaaaaa gttcacctta taagtaaact tttatttagc
     6361 tataagctaa actttattat ttttttaatt tagtatttcc aatttattgg caggattttt
     6421 gaacaatatt tataaatttt ttaaaaaaat ttaaatctat ttaatatggc agactttcat
     6481 aaaatacatt acatttatta aatgtataat attggcaatt agttttttct aaaatcagtt
     6541 gacatattat atatatattt atataatgtg tatatactat atatacaatt taaggaggtg
     6601 tcttattgaa tatagttatt agtaattcga gtgggaagcc aatatatgaa cagattacta
     6661 cacaaattaa aagtatgatt ataagtggag agttaccaga aggctcagct cttccaagta
     6721 tgagactatt ggcaaaagaa cttagaataa gtgtaattac tacaaaacga gcatatagcg
     6781 atttagaacg agacggattt attgagacag ttactggtaa aggcagtttt gtatctagta
     6841 aaaacatgga ttttgtcaaa gaagaacaat ttcgtttaat tgaagaatac ctacaaaaag
     6901 cagttgatac agcaaaaagt agtgatatta catatgacga attaaaagat attttatttt
     6961 tattatataa aggagaatga taagtatgga tgcaataact ataaaaaatt taaataaaac
     7021 ttataaagat tttagcctac aagatatatc tttttcagta ccaaaaggga gtgtaatggg
     7081 atttgtaggt gaaaatggtg caggaaaaac aactacatta aaagcaattt taaatttaat
     7141 atcttatgat agtggaaata tagaaatctt tggtcttgat agtaaaaaaa atgaaaaaga
     7201 aattaaagag caaattgggg ttgtatttga gggaagcaac tttcatgaaa atttaaacac
     7261 tgaccatgtt tcaaaaatca tgagtaaaat ctataaaaat tggaatgaca cattatttaa
     7321 agactactta aaaaaattga gagtaccaga caataaatta attaaggagt tttcaaaggg
     7381 gaataagatg aaacttagta ttgctgtagc cttatctcat aaaccaaaat tattaatact
     7441 agatgaggca actagttcac ttgaccctat cgttcgtgaa gaaatactag atatattttt
     7501 agattttata caagatgaag aacactctat tatcttatct tcacatatta caagtgattt
     7561 agataagata gcagactata ttacatttat acataaagga aaaattgtat ttagtgaaaa
     7621 taaggatgaa ttaattgata ctatgggagt tttaaaatgt aaacctagtg attttgataa
     7681 cctttcaaga gaggattatt catattatcg taaaagccaa tttggatatg aagtacttct
     7741 taaagataag catagattta tctcaagaca tccaaactgt attgttgata atacgtctat
     7801 agaagaaatt atgttatttt atgtgagagg tgataaataa tgaaaggtct aattttaaaa
     7861 gatttactta atttgaaagg aaatataaag tttatacttt tattcatcat tatgtttggc
     7921 tttatgtctt ctttaggaga tggaaatgtt aataacttta taggtgttat tatagtttta
     7981 tgtactacaa tgattgtttc aacattttca tatgatgatt tgaataaatg ggatagttat
     8041 gtacttacaa tgcctattaa tcgcaatgat attgtattaa gtaaatattt aactatgtta
     8101 atatttagct ttataggtgt tcttgtttca cttattgtta gtgtaactat tggttatttt
     8161 aaaaatacac ttatattaaa tgaaacacta cttattaatg cactaatctt atcaatttca
     8221 gtatgttttg gtagccttat tctaccactt atttataaat ttggtacaga aagagctcgt
     8281 ttattaatga ttttatgctt tttagttcca acactagctt tattagtttt taaaagtatt
     8341 ttagaaaata ttagttcacc tatttctata gaaattatac ttaatacact agtatattct
     8401 cttccatttg ttgctatttt actatttgtg atttcatatt ttatatcatc aaaaatctat
     8461 agtaaaaaag aagtataaaa tatactatat atgtttctgt atttaagtat ttaaataaaa
     8521 tactatcgag tttattttgg tagtatttta ttttttaatt attaatctct actaggtatt
     8581 tattatttta ttacttatat ttaataagac tatttactac tttctaatct tatttatata
     8641 atttattcat tttataaatt gaactactaa tgatattatt gaacatagca atagaataac
     8701 atctaaaata gtttttatgt attaaattaa cttattttaa tattcaacaa tttaggttta
     8761 ctaaatttat tgatgatttc tttttatata acttaaacta catttttatt taaaaaaatt
     8821 taatatcaac aatataaaat taagaataag tattattagt ttgacattag cataaatgcc
     8881 tattagaata atgttaaact atattctttc tactgatttt attaaaaaat accaatatac
     8941 aaaagattat acaaggagaa agttcaaata tggaattaga aattacagaa aaaatagaaa
     9001 aacaagatga agatactatt tttcaaggat tattaaaata taatcttgct agacttgaag
     9061 ataaaaaccc agtggattta ggaatatata ttcgagataa agcaggtaaa attgttgcag
     9121 gttttatagg tgttactcat ggtaattggc tttctataaa atacttatgg gttagtgaga
     9181 agcttagata taaaggtact ggaagtcaac ttttatataa ggctgaaaaa attgctaaag
     9241 aacgaggttg taaatatgtt tttttagata cattcagttt tcaagcacct aaattttatg
     9301 agaaatttgg ataccataaa gtattttcac ttgaaaatta tcctctaact ggaaagagat
     9361 attattttag aaaaatacta taataataaa aatcatattt tatattttta acttaaaact
     9421 tctgctcttc gtctacagac tttatatttt tatatcatta ttaatactaa aatagtattt
     9481 tactatacat acaaaattat ttgaaagttc aaaaattata agtataaaag ctaatcttag
     9541 cttaaataaa aattatattt ttaggaggta aatatgttag gaaaaaaatg tatggattat
     9601 ctacaaacat taggaaaaat aagttcaaca acaaatggtc ttacaagact tatcttgact
     9661 caagaacata aaaaatctat tgatttaatt agttcatgga tggaaggttt aaatcttgat
     9721 attgaaattg atgacattgg aaacgttata ggtacatata aatcaagctt tccaaatgct
     9781 cccacattag tagttgcatc tcatcaagat agtgtaaagt gtggaggtat atttgatggt
     9841 atgttaggta taatagtgcc tctagttggt cttgaagaag caaaacacaa taataggtct
     9901 tatcctttca atattaagct aattgctttc gctgaagagg aaggaactag atttgaaact
     9961 tctttaatgg gaagtaaagt ttttgctggt acttttaaag aggaacttct taaatctgtt
    10021 gatgaaaatg gaattacact tgaagaagct gtaacaaagt ttggatttaa tacaaaaaac
    10081 ttaacaaatt tgcatcctag aaaagatgta gatgcatatt tagaatttca tattgagcag
    10141 ggtcctgttt tagaaaatga atctcttcct gctggaattg tatcaagtat tacaggattt
    10201 aaaagtttta agatatcagt aaatggtaag tctggacatg ctggtacact tccaatgaat
    10261 atgagacttg atgctggatg ttgtgcctgt gaatgtgtat tagctatcga aaaagtagct
    10321 aaaacgactg ctgatttggt tgctactgta ggaaagatga atttctatcc atcttcatca
    10381 aatgtggtac ctgaaagagc tgaatttact cttgatgtac gctcttgttc acaagaaatt
    10441 cttgataatt ctgtagaaaa gatatttaat gaaatatcac atatatgtga aaatagaaaa
    10501 cttaattata caagtgaact tgcttttgaa aatgttcctg taccatgttc taataaaata
    10561 acaaaaatca tagaaaaaag ttttatagat ttaaatctta atccttttta tatttatagt
    10621 ggtgctggcc atgatgctca ggaaatggat aatataactg atattggtat ggtatttata
    10681 agatgcgctg ggggcgtaag tcataatcct aatgaaagtg tttctgtaga tgacttggat
    10741 actgctgtaa aaatattttt aaaaatacta gataatcttg atttaaaata attcttatat
    10801 aagaaagtat attaaaatat ataatctaaa aaatcacttt atatttatat tatataagtg
    10861 tacaatataa tctattataa aatataattt tatgctttta tagattttta ttttatacat
    10921 aaatatattt atatataaag gagataattt ttatgaatga aaaattaatt ggtattttgg
    10981 ctggaatggg tccaaggtca acagcccctt ttgttgattt aattattgat gagtgtcaat
    11041 ctcaatatgg agcaaaatat gatgatgaat ttccaaagat gatgatatat tcattaccta
    11101 ccccatttta tattgaccgt ccaataaatc atgaacttat gaaagaaact ataattgatg
    11161 gattacaaaa gcttgaatca actggtgtaa attttattgc aatgccatgc aattcagcac
    11221 atatatactt taaagaatta aaagagtcta ttaatatacc aatattaaat attgtagaag
    11281 aaacagttaa aaaattacct actatctcac aaaaagtaac tcttttttcg actagttcaa
    11341 cttttgagtc tacaatttac cagaatggta taatacataa tggacatgaa tttatattta
    11401 aagatgaatg gcaaataaaa ttaaacaatc ttattcaaaa tataaaaatg gataaagaaa
    11461 atccacacaa tattgatatt tggaataaac ttatcgaaga tgttaaaaat gaatctatag
    11521 aaaatatagt aattgcttgt actgatttaa atgtagtttt agaaaaatca tatccttcaa
    11581 taaatattgt tgattcatca aaatgcttgg ctgaatcagt tgtcaataaa tatctaaaat
    11641 tagttaaata aatttttcat gcactatatt ataaaaaata tatgttataa gtttatttta
    11701 aatagtatag acttataaca tatatcatag tttcttgaca atatagaaat taaccatgta
    11761 tttcattata ttaataaaaa ggataccaaa aatggtatcc ttcataaata tttatatgtt
    11821 tatttataaa aataatcata tatttattac tttactacac ctaaacaata ttattcaagt
    11881 gtattcatag agttagaaaa ttcttgtcct gctgtaacaa gattagataa caatacatca
    11941 gctactgcat catttactga acttattatc catttattat cctttttaga acattcaaac
    12001 tctacatttt ttgtaacata agtctcttta acgctttttt gtttttcttt cataattgat
    12061 actaacattt cagttgtttt ctcatcagtt aagtcttgtc ctgaaaaact cataccaatc
    12121 atctttgtaa atgcctcagc tactatttct tgaagtaatg gtgttgaatc tataaattta
    12181 cattctactt tgattgtagc cttatcacct ttaacctcgc tgtcttttat tgtatatgtg
    12241 attttagatg cattctgttt tagataatct aaaacatatt gggcatttgg gtcttttgta
    12301 tctaattcct ttaatatatc cttatatttt tcgtcattat tttccattac cttattcatg
    12361 ccttcaaagt caaacttttt cgcactgtta aaaaaactat caattgtatc ttctggtttt
    12421 gcacttgaac atgctgttaa agatattgct aataaaaaag ttgttaaagc taatatgatt
    12481 tttttcatat ctcaaatcct ccctcttaat ttgttgatac ataagttatt ttaacatata
    12541 atgagagttt ttgaataata tatttaaaat attttataaa ttttcattaa agtaaagtct
    12601 atattaaaac atatctatat taaattattg ttcatattta catcagtcat agtagaaacc
    12661 ataacagctt ttattgtatg cattctattt tcagcttctt caaatacctt tgaatatttt
    12721 gaattaaata cctcgtttgt aacctctaat tctgataatc cgaacttttc ataaatctcc
    12781 tgagcaacct tagtttctaa atcatgaaat gctggaagac agtgtaaaaa tataacattt
    12841 tcattttcag ttttctttat catatccata tttacttgat aatctttaag ttgatttatt
    12901 cttgcttcat attgctcctc ttctcccata gaaacccata catctgtata tataacatct
    12961 gcacctttaa catcatcaat attttcagtc aacattatat ctcctttgga tttcttggct
    13021 atttccttca tttccttaac caattcttca tttggccaaa gttccttagg tgctagtgct
    13081 acgaaatgta ttcccatttt agcacatcct atcatcagtg agtttcccat attatttcta
    13141 gcatcaccaa catatacaaa tttaacttta ttcaaatctt tatctacatt ttcaattact
    13201 gttaaaaaat ctgccagtat ttgtgttgga tgatattcat ctgtaagtcc attccaaaca
    13261 ggcacaccag aatattttgc tagactttca actgtttctt gtttaaagcc tctaaattct
    13321 attccatcat agaatcttcc tagaactttt gctgtatctg atacagactc ttttttaccc
    13381 atatgacaat catttggacc tagataagtt acatgtgctc cttcatcatg agctgctact
    13441 tcaaatgaac atctagttct tgttgatgtt ttctcaaata ataaagctat attttttcct
    13501 tgtagcaaat cgccttttat accaactttt ttcttagttt ttaaataact tgataaagtt
    13561 aataaatatc taatctcttc ttttgtaaaa tcctttaatg tcaaaaaact cttacctttt
    13621 aaacttatat tattcatatt aattcgcccc ttcttataaa ctttttaaat tcaattaaac
    13681 ttgttagcac tttacttttt tatttacttc taatttttat ctttaatcaa ctatttcttg
    13741 aatatttagt taatttctag taatatatct tttaggattt caagagcctc atctatttcc
    13801 ttataactga ttgttaatgg tggtaaaaat ctcaatacat tttttccagc agtcaaaata
    13861 agcaatcctt tttttctagc tttctcttct ataatactag attcaatatt agtttcaatt
    13921 cctatcatta gaccaatacc ttttgtcttt aatacaactt tgttattaaa actttcaata
    13981 gattttctta tataatttcc tttttctaat acttcattat aaaaaccatc tttagatatc
    14041 tcatctaata caactgaagc tgccaccata gctaataaat tacctccaaa agttgtacct
    14101 tggtctcctt ttcctagtac ttttgaaagt tttttattta ctaatactcc tcctactggt
    14161 attcctgctc ccaacccttt tgctacggta actatatctg gttttacatc aaaatattca
    14221 tagccaaaaa gtttaccagt tcttcctata ccgcattgga cttcatcaaa aatcactaca
    14281 atatcctttt cttgacatat ttttactatt tccaaaacat aatctttttc aagaacatta
    14341 actccacctt cgccttgaat cgcttcaaga attattgcac aaactgtgga atcaagatta
    14401 ttttttaaat cttcaatatt atttctttct acatatttaa aaccttcggg aagaggataa
    14461 aaatacttat ggtatttgtc cataccagtt gccattaaag acatcattgt tctaccatga
    14521 aaagagtctt ttaaacttat gatagttcct ctaccattac catatttgtc actactatac
    14581 tttcttgcta ttttgaatgc tgtttcattt gcttctgttc cagaattaca aaaatatact
    14641 ttagccattc cacttgaatt aattattttc tctcctgaat acaacactgg ctcattaaaa
    14701 tataaatttg aagtatgtaa taatttatct acttgctctt ttagagcatt ctttaaatta
    14761 ctattactat acccaagaga agatactcca tatccacttg taaaatctat atatttattg
    14821 ccattagtat caaaaaaaca acttccttca ccataatcta tgacaaaatt gggttgatta
    14881 tatgtatcta taaaatattc attccatttt gaaattgtat tgtcgttatt cattcttatt
    14941 ctcccctctt aaacttataa ttttattcat tttcttttct tattaatgta cctattccac
    15001 tatcagtaaa tagctctgtt attatagaat gtggaactct tccatccaaa atatgtaccc
    15061 tatttactcc gttatttaag gcatctacgc atccctctat tttaggtatc atacctccag
    15121 taattatacc ttcttcaaat aatttatcaa catcctctaa tataacttct gttattaatg
    15181 atttttcttc atctggctct cttaacaaac cagggacatc tgtaagaagt atcaatttat
    15241 ctgcatttaa ctctttagct atagcagaag ctgctgtgtc accatttata ttataagtct
    15301 ctccatcatc tccaacacct atagttgcaa ttactgaaat ataacctgac tttagacaag
    15361 attctataag ctcaacattt acttttttga tttctcctac aaatccaagt tcataatttt
    15421 tatatgggtc acataaaatc atattattat ctattccaca aagccctact gcttttccac
    15481 cttttgtatg tattttattt actaggtctt tattaacctt tccagcaagt accattttta
    15541 caatttccat ggtctcttca tctgtatatc taagaccatt tacaaattta ctttctatat
    15601 ccacttttgc tagcatctta ttgatttctg cccctccacc atgtactaaa actatattga
    15661 ttccaacata actcattaac acaaggtctt ccataacaga ttcttttaga ccatcttttt
    15721 tcattgcact tccaccatac ttaactacaa tagtctttcc ctgatgtttt tctatatatg
    15781 gtaaagcttc tataagtgta tttgcttttt ctatattaat cattaaagta tatcctccta
    15841 atttctataa cttccattta ttcttacata atcatagctt aaatcacatc cccatgcatt
    15901 tcctctggca ttgcccatat ttaaatctac taatatactt atttcgtcat cttcaaggat
    15961 tttttttgct ttttcctcat taaaatctaa tccatttcca tttttacata cttcaatata
    16021 tcctttcata ctctcaaaaa taatatcaac tttttccata tctatttctt cacctgcata
    16081 acctaaagca cacagtattc taccccaatt tgcgtcagct ccaaatacag ctgtctttac
    16141 taatgaagaa gatataactg tttttgctaa ttttactgca tgtgcttcac ttaatgctcc
    16201 atttatatag cattcaatta gttttgtaca tccttctcca tcttttgcaa caagtttagc
    16261 aagttctata cagacatatg taagtgcact caaaaatact tgataatgtt catctttttt
    16321 gtttattcta tcattttttg cttttccatt tgctagaatc attaccatat cattagtact
    16381 tgtatctcca tctacactaa ctctattaaa acttttgtca acagcaattt ttaaagcttc
    16441 ttttagcaaa actccatcaa tatttgcatc tgtagttata aatcctaacg ttgttgccat
    16501 attaggatgt atcataccag aaccttttgc catacctcca atagttattt ttttatctcc
    16561 atacattatt gctactgcta tttctttttt tataatatca gttgtcataa tagcttctct
    16621 tgctccaata tgaccttgtt tacttagatt attcactaat tcatccatat tttcttctat
    16681 taaatctata tttaatggct ttcctataac acctgtagat gcaaccaaaa catcactttc
    16741 tttaatattt aatttatcac tggtgaattt agccatttta taagcattta taagtccttc
    16801 ttttccatta aaggtattag cattagcact atttactatg atagcttgtg cttttccatt
    16861 tttaatgtgt tcctgtgtaa cataaacagg attgcccttt actttatttt gagttactac
    16921 tgctgctgca tcacataaaa catctgaata aaccaaagct aaatctcttt tttctttatt
    16981 ttttctcaag ccacagtgaa tccctgaagc aaaaaatcct tctgaaactg taactccacc
    17041 ctttataatc tccatattta tcctcctaat tatatgagtt tagtattttt tatttctaaa
    17101 atgatggtgc aatatttttt aaacctgtat tttcttcaat accaaatatt atattcatgt
    17161 tttgtatagc ttgacctgct gctcccttaa tcatattatc tatagctgaa cagattatca
    17221 atgtatctcc attttcatgt aatgatatta cacatttatt tgagaatcta acattcttta
    17281 aagaagctat cttatctaat ggaagaattt ctataaattc tttaaattca taataatcag
    17341 ttaatttcct atgtatatca tttatagaaa tattatcttc ttttgtacaa tatatagttg
    17401 ataagattcc cctatttact gggattaagt ttggtgtaaa aactacactt actttttctt
    17461 tgcaggattc acttaaattt tgttctattt ctggagtatg tctgtgtttc cctattttat
    17521 atgcagtgat attttcatta acctccgtaa agtgactact aatcgataat tctctaccag
    17581 cacctgtaag acctgattta gaatcaatta ttatattatt attttttatc aatttagaac
    17641 ttagtaatgg catcaatggt aaagaaatac tagttggata acatccagga tttgcaatta
    17701 tatctgcatc ttttatatct tctttgtata tttcacttaa tccatataca gcttttttat
    17761 gtaagatttt atctataaaa gatactccat accatttact atatacttct tcatctttta
    17821 ttctaaagtc agcacctaaa tctataactt tctttttcga tttaattgcc tttattacaa
    17881 acttttcact aactccatgt ggaagggctg taaacacaac atcacacata tctataactt
    17941 tttcattttc tatacatatc atgttatttt tatatcctat acttggatat atatcaacta
    18001 tatcttttcc aacatacgaa tttgaaccta tcgctgtcac ttcgacttta tcatgattca
    18061 ttaataatct aatcaactct gccccgacat atccagttgc accaataata ccaactttta
    18121 ttttattcat tttgttccct ccatttttat attcaaatag tcttaaaatc ctatctttcc
    18181 actttactat atgataatca tttgataata cgtagattaa aatactctaa ttaaaacaaa
    18241 aaacccctta gcattataaa tactaagagg cgattttccg cggtaccact cttattggta
    18301 aaattacaat aatcattaaa actcaaatta aaaagtatct acaaaatgta catttaaaat
    18361 taaaaaagcc tcttggtcaa agaccaagag acgaatatac acccgcgtta ccactctaat
    18421 tgataagata atcttaccca ctctaatctc ttaaggcgag attcaccaat taccatacta
    18481 ttacttctgg taatctcctc caaagctcta ttcacaataa aattcgttac taggcttcca
    18541 ccattcccag ctctctatca actagcttta tgctactctc tttttcacag gatttcaatt
    18601 tattttctta ttgttttata tgatagttta tttttttaac tttgtcaata taatttttaa
    18661 atttttggaa atattttcta tatggttaat ttccagcatt ttgtatctaa attgcgatat
    18721 aatttttata tttcattcgt caatttaaaa aacatccaaa atatattaaa ttataaaata
    18781 atatattttc aaaatacaat atttacatct ctttttaatt aaatttttta atgttggtat
    18841 ctaaaaattt ctcaatcttt ttctcagaaa gtatctcgtt ggttacaaat tcaccattaa
    18901 aaaaaagact gtatgtagta aatggtgcag gagcattttg tgcttctttt gctgtttcga
    18961 attttataag atttacatca atacctctag aatttgcaat ttttttcaaa ataggagcat
    19021 atttttccgt atgtggacac tgattactgt aatataaaac tataccattc tcatttaatt
    19081 ttctttgttt tacacaattc ttaaaacatg gaataggagc attatcagta aagggaaaat
    19141 ataatagctc ataatttggt tctgatgtat ctgctaaaca aaagtcctta tattttagat
    19201 atttagcatc agataaaaaa ggcatttttt tactagacga aagcacaact aatccatatt
    19261 taccttttga ttttgcatca tcaacacact cttgtagcaa tagattagaa tatccttgac
    19321 ccttaaattt tccagatatc caaaaacagt taataaatat ataattgtcc gcagtaatag
    19381 gacaccatgc attttctgct ggaatatatt ctataaaagc tttacctctt acatcaaatc
    19441 gtttaaagac tagaccttta tcaaaattat ttttcatcca agctttttta gaaaaaacac
    19501 aattttctcc ttttttttca gaaattgaac aacatatatg ttcattgtca atattattta
    19561 tatttatatc aataatctgc atacttatct ccttttctaa ttgcataata atttttaaat
    19621 atattctata tat
//
LOCUS       DAJMZY010000078        19501 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.078, whole genome shotgun sequence.
ACCESSION   DAJMZY010000078 DAJMZY010000000
VERSION     DAJMZY010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 19501)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19501)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19501
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.078"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            285..1583
                     /locus_tag="OE968_002637"
     CDS             285..1583
                     /locus_tag="OE968_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase/BAAT N-terminal
                     domain-containing protein"
                     /protein_id="HCP7219909.1"
                     /translation="MKVNVYNVESFVDERLKIMVSDLIPNTKLKISVKMEFPWCKGEE
                     FSSYGVFCSNEKGEVDLDLVEPIEGTYKADNCMGLIYSLEKSKTEGKNFAENISIDKP
                     IIMNMIFETSIERKEVELKRIFKSEDITTKYISDEFIGKLFYKQNSNNKTILMLGGSD
                     GNLDALDLLAAPLASRGFNVLTVAYFALEGLPDKLEEVPLEYFEKVFEWISENEITST
                     KEIFVHGTSKGGELAFLLASRYEQIKKVVVSQPHIYCFQALNGLMSGNDTSSWSYKGE
                     PFPYIKVDNDIFFEEQKKNISKDIPFGFNSTYKKSLKRAENRKEARIKIENSKADILM
                     IAGKEDNIWNSYEACLEALEIFEENNYPYNVELLTYNNMGYPLPIPYIMPLKETLCMS
                     MSRGIFSSGGTVEGNSKGQFESWNRTIEFYKKPLSSDLNN"
     gene            1773..3164
                     /locus_tag="OE968_002638"
     CDS             1773..3164
                     /locus_tag="OE968_002638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="benzoate/H(+) symporter BenE family transporter"
                     /protein_id="HCP7219910.1"
                     /translation="MERLARREQPHIKFGMFKIRIPFIHYRFEKPEAIQGIISSMTSL
                     GTIGLSTQILGLPYEVAWSMAIINSILYCLHVFMGDPVVPGWITASITLTTAYLLKFS
                     MGIERIQALTALQIDLGIIFILMGITGVAGKLVSKIPNSIKGGILMGVGISTIISEFN
                     PKGRFDSYPISITVGILVACFVMFSERFDTLKVKNKFLFHLGEYGVVSAILVSLIVGI
                     FSKEIEIPRFSFDNLVYIVDFKNLINTVSPFGIGFPSVMLFIQGIPMAFMIYIIAFGD
                     FITGENLVLSESENRKDEYIDFNSNRSNVISGIRNIFMAIFSPYIPMCGPLAATLTGS
                     VAQRYKVGKEAMQSVFSGMGTLVWVSAIFICFYPIAQIATPLIPLALSVTLLVQGYLC
                     TKLSMELCNTGVEKGLIGLMGGVIAAKGGTWGLAVGFILYFILIDSKKRKEKDINSIE
                     DCVYEILDKKKSI"
     gene            3341..3928
                     /locus_tag="OE968_002639"
     CDS             3341..3928
                     /locus_tag="OE968_002639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCP7219911.1"
                     /translation="MPPKVKITKEMILNTVLDITREVGFEAVNARSIASKLQCSTRPI
                     FTCYENMNELKNEFLAFAYEYYNQYVVNYSNSKSVSPYLLLPLSYIEFAQEETHLFKL
                     LFINDLDLMMEEANDFYKEIDNEKKARLFSESIGIELECAKVIFLDLFLYTHGIAVLT
                     ATKKLTLDRYSAEKMLKNILTAFIRQEKPDWNLSI"
     gene            3961..4752
                     /locus_tag="OE968_002640"
     CDS             3961..4752
                     /locus_tag="OE968_002640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HCP7219912.1"
                     /translation="METKQYLIDFYNTYDEDSRLALKHGMVEFLTTMHYIDKYIKSGD
                     CVLEIGAATGRYSHTLARQGYDVDAVELVEHNIEVFHKNTQSNENISITQGNAMDLSV
                     FPDNKYDITLLLGPLYHLYNKEDKQQALHEAIRVTKPGGVVFAAYVISDGCLIDEGFH
                     RGNINVSEYIEKGLIDPQTFAAKSEPKDLFELVRKENIDDLMSAFNVTRLHYVASDGL
                     ALYMREAVDSMDDDAFALYLKYHLATCEREDLVGVTSHAIDIFRK"
     gene            complement(4933..7350)
                     /locus_tag="OE968_002641"
     CDS             complement(4933..7350)
                     /locus_tag="OE968_002641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCP7219913.1"
                     /translation="MFRNNNRTFIRKIALNDLKINKLKTYLSGIIIMISTCLLLTVTL
                     VSYNASVDLVNASPYHAIYKSVDEKAKNILYKNKNFSGVGTYKLIGSNKKTDCIMSIV
                     YADDTAIKLMNFQPLKGKLPTNKNEIAISEKYLQEFGLDKDIGDSIKLNYYDDITNKE
                     VQCDFIIVGFLENYYQDNAKQYYTVVSNDYFKNIASTPLQNKSNTFDESRPDTVDVLV
                     KLSEENTEKDSASIKTQLNKIGLSLGIKKYNIYLNDNYIESNLIDGEQIITVLVVGIV
                     VLFSSVFVIYSIFYISVVNSVQMYAKLKSLGMTSFQLKKIISLQGNILSIIFIPLGVI
                     ASCIIAYIIQPLAWQMIADLFIILILSLVMFLTVRISLFKPARIISKISAIEAMQYTE
                     TKFRKKAKNFSYINIKNLALKNIESNRKKNLIALISLSISGVLFISIANLANSIDFKK
                     QLSQQFVYNEDYIISIKSDNLYEHITEIQQNNPLTDSLKNEIKSIHGVKKLIESKSIK
                     SNIIEPYIKDRDEKQFITLIKGITPELSKSLEEYIVSGKIDYTHLDSDSLIINKYRTK
                     YYGLNLKVGDTVTFNIFSGNDIIKKKMKIIGIIDNSNTGGMFFASDKTLESLTPYNTN
                     LDFSILIDKKHSKEVEEKLLSIIQKNSNLMLYSYEDDYRMITRAFQYIIIASYIFVGL
                     ISCFGILNMTNTLINSVLIRKKEFALLQAVGMTRKQLRNMLYREGLNISIKAICTSST
                     LGYFGSNLLCTFIKDVIRLDFINFKFSIFTILIFSFVLIGIQVLVTELLVRNIEKKSL
                     TERLRSQ"
     gene            complement(7363..8028)
                     /locus_tag="OE968_002642"
     CDS             complement(7363..8028)
                     /locus_tag="OE968_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCP7219914.1"
                     /translation="MSILQVINLKKYYGQSSNITKALDGVTLSIEKGEFISIVGTSGS
                     GKSTLLNMMGGLDNPTSGKVIIKGKELSTMSDEQLTIFRRRNIGFIFQNYNLVPLLNV
                     YENIILPIGLDGETIDKDFINEIINMLSLEEKLYDIPSNLSGGQQQRVAIARALVTKP
                     AIILADEPTGNLDSRTSSDVLSLLKVTSKKFNQTIVMITHNNEIAQLTDRIIRIEDGK
                     IVN"
     gene            complement(8110..9141)
                     /locus_tag="OE968_002643"
     CDS             complement(8110..9141)
                     /locus_tag="OE968_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HCP7219915.1"
                     /translation="MNFKKFSFSSIYLIIAVGIIFTAILFSISIYLITGDLKLIALLL
                     IYTMVLCGFIALIIFLLHKKIVIFCSKICHTLDSMMNSEDNIEIELEEETILSRINHR
                     LIRMYEVIQENRNSIAIEKADLQELVSDISHQIKTPIANLKMINTTLLNQTFKTEIQK
                     DFLMDMENQLDKLDFLMQSMVKTSRLETGIITLSKKKNSIYETIATALSGILFDAEKK
                     NIEVTVDCDPNLYIIHDKKWTSEAIFNILDNAVKYTSSNGKIRVATECWVMYTKIDII
                     DNGKGISESRQAEIFKRFYREEDVHDIEGIGIGLYLSRKIISLQGGYIKVTSDIGKGS
                     TFSIFLPNK"
     gene            complement(9131..9817)
                     /locus_tag="OE968_002644"
     CDS             complement(9131..9817)
                     /locus_tag="OE968_002644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCP7219916.1"
                     /translation="MEKILVVEDDSILNKTLSYNLIEDGYIITSKFTAKSALKSIFEC
                     EFDLIILDINLPDKSGFELCNEIKENYNIPIIFLTANDMECDMIKGYELGALDYITKP
                     FNINIFKQKIKAFLNHLTIKTKQDYYKDGYLEINFSELSANINGNQIIFTPLEYRTLK
                     LLTENPKSILTRKVLLEKLWDIDANFVDEHTLTSVISRIRSKIEKDNLKYIKTVYGMG
                     YMWLGERNEF"
     gene            complement(9975..11039)
                     /locus_tag="OE968_002645"
     CDS             complement(9975..11039)
                     /locus_tag="OE968_002645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S ferredoxin"
                     /protein_id="HCP7219917.1"
                     /translation="MKRVDERNTMFARANYKKDSTAYNDYYKKNPDKKEIDDSIRNRP
                     NLCSEGTMTYNELNSPMASSAFDFLSDIKSLCEGKVSDTKVDVDAKSMTKKIKGLAKQ
                     YGASVVGITKLKDYHIYTNRGRHEENYGEEINLTHKYAIVFGCEMDKEMINRAPMICE
                     VIETSKCYVDASIVGMILSYYIRNLGYDARNHMDANYLVMPVFIARDAGLGDIGRNAI
                     LTNKDYGSRLRLGVVTTDIPLLEDEYVDFGLEDFCKVCKKCSFNCPSHSLSNDIKIGD
                     DGKYNWVIEHETCYIKWRYLGTDCGMCISACPFSQNLETIKNTTSFKGNNELIQKALD
                     EYTSKFGKRIFIPGNPSWLK"
     gene            11301..11972
                     /locus_tag="OE968_002646"
     CDS             11301..11972
                     /locus_tag="OE968_002646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCP7219918.1"
                     /translation="MNLLIIEDDINLNEGLFYAFENDGFNVFKAYTKQEGLNIFNSKN
                     IDFIILDCNLPDGDGFDVCQIIREKSDIPIIMLTARDSEIDEVKGLEIGLDDYITKPF
                     SLSVLKARVKVAIRKKSNNKVIYSNGIKLDQKLLKVYKNKECLELSSVEYKLLSYLIE
                     NKGQILLKEQILHHIWDSEENYVDDNIVSVNIRRLRVKVEDDPSNPKYIKTAYGMGYL
                     WNEVE"
     gene            11974..12882
                     /locus_tag="OE968_002647"
     CDS             11974..12882
                     /locus_tag="OE968_002647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HCP7219919.1"
                     /translation="MFILAFIICTVVIFIVSTKINRKRYDELNLMLNQILEGKEVTYP
                     DTKDTRASKISHQVKKIKDMIEIEVEQSKSEKEAIKGLISNMSHQLKTPLSNITIYCE
                     LLENINISTLQKKEFLQKMKNETFKIDWLLQSLFKMTKLEDGVIEFEVEELLIKDTLI
                     QSISTIFNKAEAKNIRINLEPFSDIKLVHNKKWTIEAIVNVLENAIKYSPSDSTITIS
                     VIKMELYTKITIKDEGIGIDSRELNDIFKRFYRSKNVENQNGTGIGLYLTRLILEKEN
                     GNIIVESKLGSGCCFSIFLQNCKSLN"
     gene            12959..13645
                     /locus_tag="OE968_002648"
     CDS             12959..13645
                     /locus_tag="OE968_002648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCP7219920.1"
                     /translation="MSILVTNNLVKHYGKGETKVKALNGVSIEIERDTFTAIVGTSGS
                     GKSTLLNIIGGLDNPTSGDVIIKGKNISKIGKKDLTVFRRRNIGFIFQNYSLMPVLNT
                     YDNIALPVTLDKGNHIDHEYIEMLMKTLGIWDKRLKFPSELSGGQQQRVAIARALANK
                     PALILADEPTGNLDSKTTMEVVCLLKESSAKFHQTILMVTHNENIAQVCDSIIHIEDG
                     VVVNTGGELL"
     gene            13642..16197
                     /locus_tag="OE968_002649"
     CDS             13642..16197
                     /locus_tag="OE968_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HCP7219921.1"
                     /translation="MMSLVKFSIQYIKHYKKQSISIVLSIVLSVALLTGIGSLVHSAD
                     KSRIEKIREDSGDYHYFYKVDKEQLNKIKENKKSKEYTVDRLGVTKPKNQIDEPFIIE
                     FLNADSSYLDMTGRKLLKGTLPSKDGEIVLDTYSLNNLNVNKEIGTEINLDGKIYKLC
                     GILSSLSNPETALEGFVNDYFQPKEKDSYIVYVKYDENKNIKKQNYKFMKKFNISKEK
                     TYINWSLSVEFGVKPPKNIEKYNIFEFLKNLELNTNAIILLVGVFGAAAVYSIFHVSI
                     LQRISQYGVLEVLGANNKQLLFLLFLELFLLFIVGFPIGCFLGIGVASTIYEQFPHIF
                     LSSDIVPGAFFISEKSIYLGFLFILLLLILIAVRVVHQLNKYSSIESMKNFKITNKKK
                     RILESVKHSNMTKVLSHKYMTQKKGMFIGILFSLSLGGIIFLCSSYSIQLTKNNNELT
                     MKADDGLNSDYQITMQTTDFDVGIPKDKISRLNNVEGISKVYPVRYLFGAMQIKEEQL
                     FWKNFFKPLEKDYRIKTFFDGICTKQNEGGYLLKTNIYGYNNGMLEGLNSYIIDGEIN
                     THDMVKNNKVIVRLPMDGTGMYDAVDINPGDTIKVKVPKTMKPTDEIVKFKEENKNDY
                     TTKEFVVAATVKRVMANNIYFIGDYGMDIVMTNGQMKNNFDIENYNSVSIKKTEDSNS
                     EELSENIKSVVSDVKRCIVTDYTIAIEKNNTYLNQKLLFIYGIVFVLLAISLFHIINT
                     VSYLIFSRRHEFGILRAMGITDNKFLLMMIREGFLYGFYASIIMVIGSVIGQFMIYFM
                     VKRVYLYINPILKINTPLYIGMIILNITISIVAVIIPVRQILKSDIISEINKN"
     gene            complement(16391..17590)
                     /locus_tag="OE968_002650"
     CDS             complement(16391..17590)
                     /locus_tag="OE968_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003493023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coenzyme F420-0:L-glutamate ligase"
                     /protein_id="HCP7219922.1"
                     /translation="MDRLVGTVSRGVRAPIIRQGDDLVKIVVDSVLNASKSENFEVRD
                     KDVIAVTEAVVARAQGNYAHVDNIAKDVKDKFGDDTVGVIFPILSRNRFAICLKGIAK
                     GCRKVVLMLSYPSDEVGNHLISIDELDDKGINPWSDVLTEEKYRELFGYNKHTFTGVD
                     YVDYYKNLIKDCGAEVEIVFANNPKTILNYTTSILTCDIHTRQRTKRILRQNGAKKVY
                     SLDDIMTASVDGSGYNDQYGLLGSNKATEETVKLFPINCDEVVNKIQGNIKEITGKDV
                     EVMVYGDGAFKDPVGKIWELADPVVSPAYTKGLEGTPNEVKLKYLADNDFADLSGDEL
                     KEAISKYIVEKDNKSDDLTGNMVSQGTTPRRLTDLIGSLADLTSGSGDKGTPIIYIQG
                     YFDNYTK"
     gene            17709..18596
                     /locus_tag="OE968_002651"
     CDS             17709..18596
                     /locus_tag="OE968_002651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCP7219923.1"
                     /translation="MNIKLELYKVFNAVVNNKSFSLAAKELFMSQPAVSQSIKQLEEQ
                     LDTLLFYRNNKGVKLTPEGKILSEHVTTALKLISSGEDRINKFKKLEYGSLKIGVGDT
                     AARFFLLKYLEIFHKKYPHIHVSTINRTSRELISLLKDGNIDIAIINMPIEDDTLNIV
                     ECIEIHDIFVCANDYIEYKGRKISLEELNTLPLIMLENKANSRLYVNEYFLSKGIKLN
                     PDIELGSHELLLEFAYINLGVSCVIEEFSIDYLENEKLFKLDIKEPIPKRNIGYCHLK
                     DISLSLATKEFLSMISNNI"
     gene            18786..19343
                     /locus_tag="OE968_002652"
     CDS             18786..19343
                     /locus_tag="OE968_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCP7219924.1"
                     /translation="MSDSEYPQMKTLETRNCILRPASLDDVEDFFDCYKNKIVVKHLP
                     FSEHKSLEDTRKFIKSFFLNPYKKGKIGHFAIVYKRDNKVIGNMGFNNINPKALEAEI
                     GICINPSYWGHDFATEITKRVIQYGFRELNLNKIIAITYEENQNSTKSLDLLGFKCTG
                     KYIKKIHTGNTVKNVPCYQYELKKQ"
BASE COUNT         7295 a         2437 c         2826 g         6943 t
ORIGIN      
        1 atagtttata ttaaaaacca ttctttaaat gagtggtttt ttattttgaa tatatatatt
       61 ctaaacctaa tagcattcct atctttaatt agccaaaaat caactggatt tcatatagac
      121 cataatttta aattactaaa aaagacaata tgttgacaaa gatgaaatat gttgataaaa
      181 tgaaatagtc aatatggtgt cttaatttaa aaatttattt atcttgtatt agataaagct
      241 gttttatata aaacataaat aattattata aggagaaata gattatgaaa gtaaatgtat
      301 acaatgtaga atcatttgtg gatgaaagac ttaagattat ggtttcagac ttaattccaa
      361 atactaaact taaaataagt gtgaaaatgg aatttccatg gtgtaaggga gaagaatttt
      421 catcttatgg agtgttttgt tcaaatgaaa aaggagaagt agatttagat ttagttgaac
      481 ctatagaagg tacttataag gctgataatt gtatggggtt aatttattcg ctggaaaaat
      541 ctaaaactga aggtaaaaat tttgcagaaa atatatctat tgataaacca ataattatga
      601 atatgatatt tgaaacttct attgaaagaa aagaagttga attaaagaga atatttaaat
      661 cagaagatat taccacaaaa tacatatctg atgagtttat aggaaaatta ttttataaac
      721 aaaattctaa taataaaaca attttaatgc taggtggttc tgatggaaat ttagacgctc
      781 tagacctttt agcagctcca cttgcatcta gaggattcaa tgtactaaca gttgcatact
      841 ttgctttaga agggttacca gataaattag aagaggttcc attagaatat tttgaaaaag
      901 tatttgagtg gattagtgaa aatgaaatta ccagtactaa agaaatattt gtacatggga
      961 catcaaaggg tggagaattg gcctttttac ttgcttcaag atatgaacaa attaaaaagg
     1021 ttgtagtatc acaacctcac atttattgtt tccaagctct taatggattg atgagtggaa
     1081 atgatacttc atcatggtca tataaaggag agccatttcc atatatcaaa gtagacaatg
     1141 atatattctt tgaagaacag aaaaaaaata tatcaaaaga tattccattt ggatttaata
     1201 gtacttataa gaaaagtctt aaaagagcag agaatagaaa agaggctaga ataaaaatag
     1261 aaaattccaa agcagatata cttatgattg ctggaaaaga agataacata tggaatagtt
     1321 atgaagcttg tttagaggca ttagaaatct ttgaagaaaa taattatcca tataacgtag
     1381 aattattaac atacaataat atgggttatc cgttaccaat tccatatatt atgcctctaa
     1441 aggagacttt atgtatgagt atgagtagag ggattttttc ttcaggtgga actgtagaag
     1501 gaaattcaaa aggacagttt gaatcatgga atagaactat tgaattttat aaaaaacctt
     1561 tatcaagtga tttaaataac taatattaag tgatttaagt aactaaaaat gaagcggtct
     1621 ttctatatat gcacaaaatc tatcaatttt atagatttaa tttattgttt atataatttg
     1681 catgttatat actaatttta atgacattga taatttataa acaattataa agttgtaaac
     1741 ttataagagt tattgaaagg tggagtgaag ttatggaaag actcgctaga agggaacaac
     1801 ctcatataaa atttggaatg tttaagataa gaattccatt tatacattac agatttgaga
     1861 aaccagaagc tattcaaggt ataatatcaa gtatgacaag tttaggcaca attggcctta
     1921 gtacacaaat tttgggatta ccctatgaag tggcatggag tatggctatc attaactcaa
     1981 tattatactg tttgcatgtt tttatgggag acccagttgt acctggctgg attacagctt
     2041 ctataactct tacaactgca tatttgttaa agttcagcat gggcattgaa agaatacaag
     2101 cattaacagc tttacaaata gatttaggaa taatatttat tttaatgggt ataactggtg
     2161 tagctggaaa gttagttagt aagataccaa attctattaa aggtggaata ctaatgggtg
     2221 tcggtatatc gactataata tcagagttta atcctaaagg gagatttgat tcttatccta
     2281 tatctataac agtaggaatt ttggttgctt gttttgtaat gttttctgaa agatttgata
     2341 ctctaaaagt taagaataaa tttttatttc atttaggaga atatggtgta gtatcagcta
     2401 ttttagtgag tttaatagta ggtatattta gtaaagaaat agaaattcct agatttagtt
     2461 ttgacaattt agtttacata gtagatttta aaaatctgat aaatacagta tctccttttg
     2521 gaataggttt tccaagtgta atgttattta tacaagggat accaatggct tttatgatat
     2581 acataattgc ctttggtgat tttataacag gtgaaaactt agtactttct gaaagtgaaa
     2641 atagaaaaga tgaatatata gatttcaatt caaataggtc taatgttata agtgggataa
     2701 gaaatatttt tatggcaatc ttttctccat atataccaat gtgcggtcca ttagctgcga
     2761 cacttacagg aagtgttgct caaaggtaca aggttggaaa ggaagccatg cagtctgttt
     2821 ttagtggcat gggtacatta gtatgggttt cagcaatttt tatctgtttt tatccaattg
     2881 cgcagattgc tacacctctt ataccattag cattgtcagt aacactttta gttcaaggat
     2941 atttatgtac aaagctatca atggagctat gtaatacagg tgttgagaag ggattgattg
     3001 gacttatggg aggtgtaatt gctgctaaag gcggaacatg gggacttgct gtaggtttta
     3061 tactgtattt cattttaatt gattctaaaa aaagaaaaga aaaagatatt aattcaatag
     3121 aagattgtgt atatgaaata ttagacaaaa agaagagtat ttaaaggaaa atctgagttg
     3181 ctgttatcta ttaatagatt aattgcaact catgttttat ttataagttt taggaattgc
     3241 aaaaaaatgc aaagcttttt cttgacataa tttcttgata tgttactata gttatataac
     3301 atatgtgttt tataaaaatt taatggagag gtgaacatat atgccaccta aagtaaagat
     3361 aacaaaagaa atgattttga atacagtctt ggatattaca agagaagtgg gatttgaagc
     3421 tgtaaatgcg aggagtattg caagtaaatt acagtgttcc actcgaccaa tttttacttg
     3481 ttacgaaaac atgaatgaat taaaaaatga atttcttgct tttgcatatg aatactataa
     3541 tcagtatgtt gttaattata gtaattctaa aagtgtaagt ccttatttac tgcttccgct
     3601 ttcatacatt gaatttgctc aagaagaaac tcatttattt aagttgttat ttataaatga
     3661 tttagatttg atgatggaag aggcaaatga tttttataaa gaaattgaca atgaaaaaaa
     3721 ggcaagactt ttttcggaaa gcattggaat agagttggaa tgtgcaaaag taatattttt
     3781 agatttattt ctttatactc atggcatagc tgtcttaaca gcaacaaaaa aattaacatt
     3841 agatagatat agtgctgaaa aaatgttgaa aaatatatta acagctttta taagacaaga
     3901 aaaaccagat tggaatttgt ctatttgatg tttattaact aatatagaag aggtgaaatt
     3961 atggaaacaa aacaatactt aattgacttt tataatactt atgatgaaga tagtcgactt
     4021 gcattaaaac atggaatggt ggaatttctc actactatgc attacattga taagtacata
     4081 aaatcaggtg attgtgtgct tgaaattggc gctgcaactg gtcgttattc tcacacactg
     4141 gcacgtcagg gatatgatgt tgacgcagtg gaattagtcg aacataatat agaggttttc
     4201 cataaaaata ctcaatcaaa tgaaaatata agcattactc agggtaatgc tatggattta
     4261 tctgttttcc cagataataa atatgatatt acgttactgt taggaccact atatcatctt
     4321 tataacaaag aagataaaca acaagcttta catgaggcaa ttcgtgtaac aaaacctggt
     4381 ggtgtggttt ttgctgcata tgttatatct gatggctgtc tcattgacga ggggttccat
     4441 agaggaaata ttaatgtatc tgaatatatt gaaaaaggtt tgattgatcc acagacattt
     4501 gctgctaagt ctgaaccaaa ggatttgttt gagcttgtac gtaaagaaaa cattgatgat
     4561 ttgatgtctg catttaatgt aactagactg cattatgtcg catcagatgg tttggcttta
     4621 tatatgcgtg aagcagtaga ctctatggat gatgatgcat ttgcattata tttaaaatat
     4681 caccttgcta cttgtgaacg tgaagattta gtaggggtta caagtcatgc aattgacata
     4741 tttagaaaat aaggaatatg cttgtttatg tctctggtga tgttgctcgg agatataagt
     4801 aagtgtatct gtataaaata aaaacaagta tagggataga aaattatgta aagtcaaaat
     4861 tttctatccc tatagctttt aaaaaatcat attaaaactt gtataaaaaa tggctatttt
     4921 ttatatacat tcttactgag aacgtaagcg ttctgtaagt gatttttttt ctatatttct
     4981 tacaagtaat tcagtcacta aaacttgtat accaattaat acgaatgaaa aaattaaaat
     5041 agtaaatata gaaaatttaa aattaataaa gtctaatcta attacatctt ttataaaagt
     5101 gcaaagtaga tttgaaccaa aataacctag tgtacttgaa gtacatatag ctttgatact
     5161 tatgtttaga ccttctctat aaagcatatt tcgcagttgc tttcttgtca ttccaacggc
     5221 ttgaagtaat gcaaactctt tttttctaat taaaacgctg tttattaggg tattggtcat
     5281 atttagtata ccaaagcaag aaattaaacc aacaaaaatg tatgaagcta taattatata
     5341 ttgaaatgct ctagtaatca ttctataatc atcttcatat gaataaagca ttaaatttga
     5401 atttttctga attatactta acaacttttc ttcaacttct ttagaatgct ttttatctat
     5461 taaaatagaa aaatctaaat ttgtattata tggtgttaga gattctaaag ttttgtctga
     5521 agcaaaaaac atacctcctg tattggaatt gtcaatgatt cctataattt tcattttctt
     5581 tttaataata tcatttccac taaagatatt aaatgtaact gtatctccaa cttttaaatt
     5641 taatccataa tattttgttc tatatttatt tataattaaa ctatctgaat ctaaatgtgt
     5701 atagtctatt tttccactga caatatattc ttcaagtgat tttgaaagtt caggcgtaat
     5761 acctttaatt agagtaataa attgtttttc gtctctatct ttgatgtaag gttctataat
     5821 attactttta attgatttgg attcaattaa tttttttact ccatgaatag atttaatttc
     5881 attcttaaga gaatctgtta gtggattatt ttgttggatt tctgtaatat gctcatataa
     5941 gttatcactc ttaatgctaa ttatataatc ttcgttatag acaaattgtt gagatagttg
     6001 ttttttgaaa tctattgaat tagcaagatt agcgattgaa ataaataaaa ctccactaat
     6061 gcttagcgat attaatgcaa tcaaattttt ctttctattt gactcgatat tctttaatgc
     6121 tagatttttt atatttatat aactaaaatt ttttgctttt tttctaaatt tagtttctgt
     6181 atattgcatg gcttcaatag cagatatttt agaaataatt ctagctggtt taaataaaga
     6241 aattctaaca gttaaaaaca ttaccagtga taaaattaaa attataaata aatcagctat
     6301 catttgccat gctaatggtt gaattatgta agcaattata caagaagcta taacccctaa
     6361 tggaataaaa ataattgaca aaatatttcc ttgtagagaa ataatttttt ttaactgaaa
     6421 agaagtcata cctaacgatt tcaacttagc atacatctga actgaattaa caactgaaat
     6481 ataaaaaata ctatatataa caaaaacgct agaaaaaaga acaactattc caactactaa
     6541 aactgtaata atctgctcac catcaattaa atttgattca atatagttat catttaagta
     6601 tatattatat ttcttaatac ctaaagataa accaatttta tttaactgtg tcttaattga
     6661 agctgaatct ttctctgtat tttcttctga tagtttaact aatacatcta cagtatcagg
     6721 tcttgactcg tcaaaagtat tacttttatt ttgtaaaggt gtagaagcta tattcttaaa
     6781 ataatcattt gaaacgactg tatagtattg cttggcatta tcttgataat aattttctag
     6841 aaatccaaca ataataaaat cacattgaac ttctttattc gtaatatcat cataataatt
     6901 taatttaatg ctatctccaa tatctttatc taaaccaaat tcctgtaaat atttttctga
     6961 aatagcaatt tcatttttat ttgtaggtag tttgcctttc aatggttgaa aattcataag
     7021 tttaattgct gtatcatctg cataaacaat cgacataata caatctgtct ttttattact
     7081 tccaattaat ttgtaagttc ctacgccact aaagttttta tttttatata gtatattttt
     7141 tgctttttca tctacagatt tatatatagc atgatatgga gatgcattaa ctaaatctac
     7201 agaggcatta tatgaaacta aggtcactgt taataataaa catgtagaaa tcattataat
     7261 gatacctgaa agatatgttt taagtttatt aatttttaaa tcatttaaag ctatttttct
     7321 tataaatgtg cgattattat ttctaaacat atactacacc tcctagttaa caatttttcc
     7381 atcttcaata cgaataattc tatcagttag ttgtgcaatt tcattattgt gtgtaatcat
     7441 tacaattgtt tggttgaatt ttttacttgt cactttaagt aaactcagta catctgaact
     7501 agttctacta tcaaggttac ctgttggttc atcagctagt ataatagctg gttttgttac
     7561 aagtgctcta gctatagcaa cacgttgctg ttgaccacca gaaagattac ttggtatatc
     7621 atataatttt tcttcaagag aaagcatatt tataatttca tttataaaat ccttatctat
     7681 ggtctctcca tccaatccta ttggtaagat aatattttca tatacattaa gtaaaggaac
     7741 aagattataa ttttgaaata taaaacctat atttctgcgt ctaaagattg taagctgttc
     7801 atcagacata gtagataatt ccttaccctt tataataacc tttccagatg taggattatc
     7861 taatcctccc atcatattta ataatgtgga tttgccacta ccagatgtac ctacaataga
     7921 aataaattcg cctttttcaa tagatagagt tacaccatca agagcttttg taatgtttga
     7981 actttgtcca taatatttct ttaaattaat tacttgtaaa atactcataa taatacctcc
     8041 ttaacatctt gtaaatacag tataaaacca aaatgttgca gaatcattac aaatgaaatt
     8101 tttaaaaatt tatttattag gtaagaaaat agaaaaagtc gacccttttc caatatctga
     8161 tgtaacttta atatagccac cttgaagaga tataattttt cttgaaagat agagacctat
     8221 tccaatacct tctatgtcat ggacatcttc ttcacgataa aatcttttaa agatttctgc
     8281 ttggcgactt tctgatattc cttttccatt atcaataata tctatttttg tatacataac
     8341 ccaacattct gtagctacac gtatcttacc attagaactt gtgtatttta cagcattatc
     8401 taatatatta aaaatagctt cagaagtcca tttcttgtca tgaattatat ataaatttgg
     8461 gtcacaatca actgtaactt caatattctt tttttcagca tcaaacaaaa ttccactaag
     8521 tgctgtagca attgtttcat aaattgaatt tttcttttta gatagtgtga ttatacctgt
     8581 ctctagtctg gaggttttta ccatagattg cattaaaaaa tctaatttat ctaattggtt
     8641 ttccatatcc attaaaaaat ccttttgaat ttctgtttta aatgtttgat ttagtagagt
     8701 agtattaatc atttttaaat ttgcaatagg agttttaatt tgatgagata tatcagaaac
     8761 tagttcttgt aaatcagctt tctctatagc aatactattg cgattttctt gaataacttc
     8821 atacattcta attaatctgt gattgatacg tgataaaata gtttcttctt ctaattcaat
     8881 ttcaatatta tcttcactat tcatcatact atctaaagtg tgacatattt tagaacaaaa
     8941 tataactatt tttttatgaa gtaaaaatat tattaatgct ataaatccac aaagtaccat
     9001 tgtatatatt aataatagag caattagttt taaatcacca gttattagat aaattgagat
     9061 actaaataaa atagctgtaa aaattatacc aacagcaatt attaaataaa tagaactaaa
     9121 agaaaatttt ttaaaattca tttctttcac ctaaccacat atatcccata ccatataccg
     9181 ttttgatata cttaagattg tctttttcaa ttttgcttct aatcctactt ataacagatg
     9241 ttaaagtatg ttcatctaca aagttagcat ctatatccca gagtttttct aaaagtactt
     9301 tccttgttaa aatactttta ggattttcag taagcagttt taaagtacga tattctaatg
     9361 gtgtaaatat aatttgattt ccatttatat tggcagataa ctcagaaaag ttaatttcaa
     9421 gatatccatc cttatagtaa tcttgttttg tttttattgt aagatgattt aaaaaagctt
     9481 taattttttg tttaaatata ttgatattaa atggttttgt tatataatcc aaagctccaa
     9541 gttcatagcc tttaatcata tcacattcca tatcattagc agttaaaaaa attattggta
     9601 tattgtaatt ttcctttatt tcattacata attcaaaccc acttttatct ggtaaattaa
     9661 tatccaaaat tattaaatca aattcacatt caaaaataga ctttagtgca gatttagctg
     9721 taaattttga agtaattata tatccatctt caattaggtt atatgataga gttttattta
     9781 atatagaatc atcttctact actaatattt tttccataca gttactcctt ttagtttaat
     9841 attttataat gtcaattata gactaaaaac attgctgaat tgttataaac gagaaaaagt
     9901 atttaaaaat ttatatattt aataaagaac ctgtcctatg ataaattcta gtacagattc
     9961 tttattaaat aaaattattt caaccaagat ggatttccag gtataaatat tcttttacca
    10021 aattttgaag tatactcatc taaagctttt tgaataagct cattattacc cttaaatgaa
    10081 gtagtattct ttatagtttc gagattttgg ctaaatgggc aagcagatat acacatacca
    10141 caatctgtac ctaaatatct ccatttaata tagcatgtct catgttcaat tacccaatta
    10201 tattttccat catcaccaat tttaatatca ttagaaagcg aatgagaagg gcagttaaaa
    10261 gagcattttt tacagacctt acaaaaatct tctagtccaa aatcaacata ttcatcttct
    10321 aaaagaggaa tatctgtagt aacaacacct aatctaagtc tagagccata atctttattt
    10381 gtaagtatag catttcttcc tatatctcct aaaccagcat cacgagctat aaaaacaggc
    10441 attactaaat aattagcatc catatgattt ctagcatcat atcctaaatt tcttatatag
    10501 taacttaaaa tcatgccgac gatagatgca tccacatagc actttgatgt ttctataact
    10561 tcacatatca ttggagctct atttatcatt tctttatcca tctcacatcc aaatacaatt
    10621 gcatacttat gagttagatt aatttcttca ccgtaatttt cttcatgtct acccctattt
    10681 gtataaatat gatagtcttt taatttagtt ataccaacta cagaagctcc atactgcttt
    10741 gcaagaccct taattttttt tgtcattgac tttgcatcta catctacttt agtatcagaa
    10801 acttttcctt cgcataaaga tttgatatca gataaaaaat cgaatgcact acttgccatt
    10861 ggagagttta actcattgta agtcattgtt ccttcactac ataaatttgg tctatttctt
    10921 atactatcat caatttcttt tttgtcagga tttttcttat aatagtcatt ataagcagta
    10981 ctatcttttt tgtaatttgc tcttgcaaac atagtatttc tctcatcaac ccttttcaat
    11041 tctattcccc ctagtaaaaa tatatttaaa aaatataact ttattgttgt ataatttaat
    11101 tatataagaa taaagttata ttttcaattt aagcgtaatt aaattgggaa atatataact
    11161 atatgcttga ttataatgtt tttattttga aaacaaattt aaatacaatc tttttagtga
    11221 aataaataaa attaaaatat ttttagtatg ataatgcaag aaaataatta tttatctaaa
    11281 aaatctaaag gagagtaaaa ttgaacttat taattattga agatgatata aacttaaatg
    11341 aaggtctttt ttatgcattt gagaatgatg gatttaatgt atttaaggct tatacaaaac
    11401 aagaaggatt aaatatattt aatagtaaaa atatagattt tataatctta gactgcaatc
    11461 ttccagatgg agatggattt gatgtatgtc aaataataag ggaaaagtca gatataccaa
    11521 ttataatgct tactgcaaga gactcagaaa ttgatgaagt aaaaggatta gaaatagggc
    11581 ttgatgatta tattacaaaa ccattttctt tatctgtatt aaaggcaaga gtcaaagtag
    11641 caataagaaa aaaatcgaat aataaagtaa tatattccaa tggaataaaa ttggaccaaa
    11701 agttactaaa agtatataaa aataaagaat gtttggaact tagctctgta gaatataagc
    11761 ttctaagtta tctaattgaa aataaaggtc aaatattatt aaaggaacaa attttacacc
    11821 atatttggga cagcgaagaa aattatgttg atgataatat tgtatctgta aatataagaa
    11881 gacttagagt aaaagtagag gatgacccat ctaatccaaa atatataaaa acagcttatg
    11941 gaatgggtta tttatggaat gaggtagaat aatatgttta tattagcctt tataatatgt
    12001 acagttgtta tatttatagt atctactaaa ataaatcgaa aaagatatga tgaattaaat
    12061 ttgatgttaa atcaaatatt ggaaggtaaa gaagttactt atccagatac aaaggataca
    12121 agagcgtcaa aaatttctca ccaagtaaaa aaaattaagg atatgataga aatagaggta
    12181 gaacagtcaa agtcagaaaa agaagcgatt aaaggtttaa tatcaaatat gtcacatcaa
    12241 ttaaaaactc cactttcaaa tataaccatt tattgtgaac ttctggagaa tataaatatt
    12301 tccacattac agaagaagga gtttttacaa aagatgaaaa atgaaacttt taagattgac
    12361 tggctgttac aatccttatt taaaatgact aaattagagg atggagttat agaatttgaa
    12421 gtagaagaac tactaattaa agatactctt attcaaagta tcagtactat ctttaataaa
    12481 gcagaagcta aaaatataag gataaatctc gaaccatttt cagacataaa attagttcat
    12541 aataaaaagt ggaccataga agcaattgta aatgttttag aaaatgcaat aaaatactca
    12601 ccatcagata gcacgattac tatttctgta ataaaaatgg aactatatac gaagattact
    12661 attaaagatg agggaatagg tattgatagt agagaactaa atgatatttt taaaagattt
    12721 tacagaagta aaaatgttga aaaccaaaat ggcacaggga ttggtctata tcttacaaga
    12781 ttaattttag aaaaagaaaa tggaaacatt atagtagaat ctaaactagg aagtggatgt
    12841 tgttttagta tcttcttaca gaattgtaag agtttaaact aattttgtag gatgagtgta
    12901 attatcgtca cttacaatat tttatagaac atatatctgt attgaaagga gaaattaaat
    12961 gagtatatta gtgacgaata atttagtaaa acactatgga aaaggtgaga ctaaagtaaa
    13021 agccttaaat ggagtaagta tagaaattga acgagataca tttactgcta tagttggaac
    13081 ttctggttct ggaaaaagca cattgttaaa tattataggt ggattagata atccaacctc
    13141 aggtgatgta ataattaaag gaaagaacat atctaaaata ggaaaaaaag atttgacagt
    13201 gtttagaaga agaaatatag gatttatatt tcaaaactac agtttaatgc ccgtattaaa
    13261 cacttatgat aatatagctc ttcctgttac attagataaa ggaaaccata tagaccatga
    13321 atatattgaa atgctgatga agacattggg aatttgggat aagcgtttaa aatttccaag
    13381 cgaactatct ggtggtcaac aacagagggt agcaattgct agagctttgg caaataaacc
    13441 tgcgcttata ttagcagatg aaccaacagg aaatctcgat agtaaaacta caatggaagt
    13501 ggtatgttta ttaaaagaaa gtagtgcaaa attccatcaa acgatactta tggtaacaca
    13561 caatgaaaat atagcacaag tatgcgactc aattatccat attgaagatg gagttgtggt
    13621 taatactggt ggtgaattac tatgatgtct ctagtaaaat tttcaattca atatataaag
    13681 cattataaaa aacaatctat atctatagtt ttaagcatag tactatcagt agcattattg
    13741 acgggaattg gttctttagt tcatagtgca gacaaaagta gaattgaaaa gataagggaa
    13801 gatagtggag attatcatta tttctataaa gtagataagg aacaacttaa taaaattaaa
    13861 gaaaataaaa aatcaaagga atacactgta gatagacttg gcgttacaaa acctaaaaat
    13921 cagatagatg aaccttttat tatagaattt ttaaatgctg attcttcata tttagacatg
    13981 acaggtagaa aattattaaa aggaactctt cctagtaaag atggagagat agtacttgac
    14041 acatattctc taaacaattt aaatgtaaac aaagaaattg gaacagaaat caatttagat
    14101 ggtaaaatct ataagttatg tggtatttta tcaagtcttt caaacccaga aactgctctg
    14161 gagggatttg taaacgatta ttttcagcct aaagaaaagg attcttatat agtttatgta
    14221 aaatatgatg aaaataaaaa tattaaaaag caaaattata aatttatgaa aaaattcaac
    14281 atatcaaaag aaaaaactta tataaactgg tctctttcag ttgaatttgg agtaaaacca
    14341 ccaaaaaata tagaaaaata taatatattt gagttcttaa aaaatttaga actaaataca
    14401 aatgcaatta tattgcttgt tggagtgttt ggtgcagcag cagtatatag tattttccat
    14461 gtttcaatac ttcagagaat atcacaatat ggggttttag aagtattagg cgctaataat
    14521 aaacaacttt tatttctact atttttagag ttatttttac tttttattgt tggatttcct
    14581 ataggttgct tcttaggtat tggagtagcg tctacaatat atgaacaatt tccacatata
    14641 tttttgagta gtgatattgt tccaggagca ttttttataa gtgaaaaatc tatttattta
    14701 ggctttttat ttatcttatt gttgttaatt ttaattgctg tacgtgttgt acatcagttg
    14761 aataaatact ctagtataga atctatgaaa aactttaaga ttactaataa gaaaaagaga
    14821 atattagaaa gtgtaaaaca ctctaacatg acaaaagtat tatctcataa atacatgact
    14881 caaaaaaagg gaatgtttat tggaattttg ttttcattat cacttggtgg aattatattt
    14941 ctatgttcta gttactctat acagcttact aaaaataata atgaacttac aatgaaagct
    15001 gatgatggtt taaattctga ctaccaaata actatgcaaa caacagattt tgatgtaggt
    15061 ataccaaaag ataaaatttc aagattaaac aatgttgagg gaatatcaaa agtctatcca
    15121 gtaagatatt tatttggagc tatgcaaatt aaagaagaac aactattttg gaaaaatttc
    15181 tttaaacctc ttgaaaaaga ttacaggata aagacttttt ttgatggtat ttgtacaaag
    15241 caaaatgaag gtggctatct tttaaaaaca aatatttatg gttataacaa tggtatgtta
    15301 gaaggattaa attcttatat tatagatggg gagattaata cccatgatat ggttaaaaat
    15361 aataaggtta tagttagact acctatggat ggaactggga tgtatgatgc agttgatata
    15421 aatccaggag atacaataaa agttaaagtg ccaaagacaa tgaaaccaac agatgaaatt
    15481 gttaaattta aagaagaaaa taagaatgat tatacaacaa aagaatttgt agttgctgct
    15541 actgtaaaac gtgtgatggc aaataacata tatttcattg gtgattatgg tatggatata
    15601 gttatgacga atgggcaaat gaaaaataac tttgatatcg aaaattataa ttcagtaagt
    15661 ataaaaaaga cagaagatag taacagtgag gaattgtctg agaacataaa aagtgttgta
    15721 agtgatgtaa aaagatgtat cgtaacagat tataccattg ctattgaaaa aaataatacc
    15781 tacttaaatc aaaaactctt atttatatat ggtattgtat ttgtacttct tgcaataagt
    15841 ttgttccata taatcaatac agtaagctac ttaatttttt caagaagaca tgagtttgga
    15901 attttaagag ctatgggtat tacggataat aagtttttac ttatgatgat aagagaaggt
    15961 tttttatatg gattctatgc aagtattata atggtaattg gaagtgttat tggacaattt
    16021 atgatttatt ttatggtaaa acgtgtatat ttatatataa atccaattct taaaataaat
    16081 acacctctat acataggtat gattatttta aatatcacta ttagtatagt tgctgtaatt
    16141 attccagtaa gacaaatttt gaagagtgat attatttcag aaataaataa gaattagagt
    16201 tatataaatt tttaagatta tataactttc tgacaatctt gtttaaatta tttaaatata
    16261 tcttatctgt gaacattaaa taaacctctt aatagatata actcttgaaa agtcatatct
    16321 attaagaggt tttaataaat tttcatgtta atatatataa tccaaaaaaa ttaaatctta
    16381 ttaaaacata ctattttgta tagttatcga aatatccttg tatgtaaata ataggagtac
    16441 ccttatctcc acttccagat gttaaatctg ctaaagaacc tataaggtct gttaatcttc
    16501 ttggagtagt accttgagaa accatgtttc ctgttaaatc atcagattta ttatcttttt
    16561 caactatgta ttttgaaatt gcttctttta actcatcacc agataagtca gcaaaatcat
    16621 tatctgctaa gtattttaat tttacttcgt ttggagttcc ctctagccct tttgtataag
    16681 caggagatac tactgggtca gctaattccc atattttacc tacagggtct ttaaaagctc
    16741 catctccata aaccattact tctacatctt tccctgttat ttcttttata ttaccttgga
    16801 ttttgtttac aacttcatca caatttatag ggaataattt tactgtttct tctgtagctt
    16861 tgtttgaacc taaaagtcca tactggtcat tgtaaccact accatctaca cttgctgtca
    16921 ttatatcatc aagtgaatat acttttttag ctccattttg tcttaaaatt ctctttgttc
    16981 tttgtcttgt atgtatatca caagttaaaa tacttgttgt atagttaaga atagtttttg
    17041 gattgtttgc aaatactatt tctacctctg caccacaatc cttgattaaa ttcttataat
    17101 aatcaacata atctacacca gtaaatgtat gcttgttata tccaaatagt tctctgtatt
    17161 tttcttctgt taaaacatct gaccaaggat ttattccctt atcatcaagt tcatcaatac
    17221 ttattaagtg atttccaact tcatcagaag ggtagcttaa cattaatacg acttttctac
    17281 atccttttgc aattcctttt aaacatatag caaaacgatt tctacttaaa attgggaata
    17341 taaccccaac agtatcatct ccaaatttat cttttacatc ttttgcaata ttgtcaacgt
    17401 gagcataatt tccctgtgct ctagctacaa cagcttctgt aacggcaatt acatctttgt
    17461 ccctaacttc aaagttttca ctttttgacg catttaaaac agaatcaaca actattttaa
    17521 ctaagtcatc tccttgtctt ataataggtg ctctaacccc tcttgaaaca gttccaacta
    17581 atctatccat tatctaaaat cctcctaaag aattaatatt gtcatattag taccatgtat
    17641 attataattc aaatataatt ataagtaaaa taaataatac taatatttga cataaggagt
    17701 aattatatat gaatataaaa cttgaacttt ataaggtttt taatgcagtt gtaaataata
    17761 agagtttttc tcttgctgct aaggaattgt ttatgtcaca gccagctgta agccagtcaa
    17821 taaagcaatt agaagaacaa ttagatactt tattatttta tagaaacaat aagggagtaa
    17881 aattaactcc agaggggaaa attctaagtg aacatgtcac tactgcatta aagttaatat
    17941 catcaggaga agatagaata aataaattta aaaaattaga atacggttct ctgaaaatag
    18001 gagtaggaga tacagctgca cgttttttct tgttaaaata tttagaaatt tttcataaga
    18061 agtatccaca tatacatgta tctacaataa atagaacgag tagagaactt atatctttac
    18121 tcaaagatgg gaatatagat atagcaatta taaacatgcc aatagaagat gatacactaa
    18181 atattgttga gtgtattgaa atacatgata tatttgtatg tgcaaatgat tacatagaat
    18241 acaaaggtag gaaaatatca ttggaagaat taaacacatt gcctttaata atgctagaaa
    18301 ataaagcaaa ttcaagactt tatgtaaatg aatatttttt atcaaaaggt ataaaactaa
    18361 acccggatat agaattgggt tctcatgaat tacttttaga atttgcgtat ataaatcttg
    18421 gagtgtcttg tgttatagaa gaatttagca tagattattt ggaaaatgag aaattgttta
    18481 aattagatat aaaagagcca atacctaaga gaaatatagg ttactgccat ttaaaagata
    18541 tatctttatc cttagcaacc aaagaatttt taagcatgat atctaataat atataattta
    18601 gaatacatat ttcacaagta atttaatata aaaatagaga taaattcgta aatttgaaag
    18661 attcatatag taattagttt ttattaaaaa taaaaataag gttaatttga gaacatttat
    18721 ataattaata tcgtatttta aatatgaaca gtatatttag attaatgtat aaagggggat
    18781 tagaaatgtc tgattctgaa tatcctcaaa tgaaaacctt agaaactaga aattgtatac
    18841 taagacctgc atcattagat gatgttgaag atttttttga ctgttataaa aataaaatag
    18901 tagtaaaaca tttaccattt agtgagcata aatctttaga agatacaaga aagtttataa
    18961 aatcattttt tctaaatcca tataaaaaag ggaaaattgg ccactttgct atagtatata
    19021 aaagagacaa taaagttatt gggaatatgg ggtttaataa tataaatcct aaagcattag
    19081 aagcagaaat aggtatatgt ataaatccaa gctattgggg acatgatttt gctactgaga
    19141 taacaaaaag agtaatacag tatggattta gagaactaaa cttaaataaa ataattgcaa
    19201 taacctatga agaaaaccaa aattctacaa aatcattaga tttattagga tttaaatgta
    19261 caggaaagta tatcaaaaaa attcatactg gaaatactgt gaaaaatgtt ccttgttatc
    19321 aatatgaatt gaaaaaacaa tagatataat catttaatat ctatgctggt tatttagtaa
    19381 tgattgtttt ctaaataaaa tttcaataaa gtggttgcct caaaatatag ataatcctgt
    19441 ttttattgtt aaaatactga aaatgcattt gattttatac aaaaaagagt gtctcatgaa
    19501 c
//
LOCUS       DAJMZY010000079        19103 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.079, whole genome shotgun sequence.
ACCESSION   DAJMZY010000079 DAJMZY010000000
VERSION     DAJMZY010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 19103)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19103)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19103
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.079"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            193..705
                     /locus_tag="OE968_002653"
     CDS             193..705
                     /locus_tag="OE968_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219925.1"
                     /translation="MKVKKFKSGIVMALTVMAIGASLTNVSAMELNKSKEFETKYNEM
                     KMDFQEEYGKEDKFNITLDDEFTKEEVNGAKGIIKTTNKMNNEVVVLNYFDEMKSGIE
                     FELKPKAEKNAILRDEFQQGYGKEDKFKVVLDDEFTKEEVNGAKGIIKTTDKETGEVI
                     VYNYFDELEK"
     gene            complement(1158..2255)
                     /locus_tag="OE968_002654"
     CDS             complement(1158..2255)
                     /locus_tag="OE968_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--glyoxylate aminotransferase family
                     protein"
                     /protein_id="HCP7219926.1"
                     /translation="MKKTYLFSPGPVMVTDKVRNSLLHYDICHRGNEFMDLFKDTQQK
                     INKLYNATSNYYSLIVSGSGTSVNECVLSSIFDKEDAVLLVSNGVFGERLEEILSTYN
                     VKTYKPNFEWAEYPDLDILEKYIIENSDIKVIAMVFHETSSGMINPVPELGKLAKKYN
                     KIFFVDAISASAGEYIDVEEFNIDIITGVGGKALGAFPGSAYLCAKESILQNIKENQC
                     KNVYLNLYKHYKVAKSSSQTPNTPNVTLIFALNEALTEFLEDDSKIERYKECSAILRN
                     GMEELGLTFLLPDKYMSNTVTSVFLPKEINVNEFILGLERESGYVVYPGKGKFLDANI
                     FQVANMGEIYPEDCYKFLDILKSKLEIKKVI"
     gene            2548..4074
                     /gene="glpK"
                     /locus_tag="OE968_002655"
     CDS             2548..4074
                     /gene="glpK"
                     /locus_tag="OE968_002655"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HCP7219927.1"
                     /translation="MKYVLAIDQGTTGTRAVLINEKSEFVFSDYMEHTQIYPQSGYVE
                     HDPIEIWNNTKTVSNNVLQQAFENGINESDIKGIGIDNQGETVMLWDKNTGKPLYNAI
                     VWQCRRTYDYVENLKNIPGLENKIIDKTGLIIDPYFSGTKIKWVIDNVKGVKEKIKNG
                     EVLAGTLDSWLIWKMTGGKSFLTDVSTAARTMLFNIRDMDWDRELLDIIGVPRSILAD
                     IMPTSGDFGTTDKEAFCGVSIKITASMVDQPAALFGNGCFEPGMVKNTYGTGCFLYMN
                     IGEELNIAGNGILTTVAWKIGDKVTYAYDGGVYIAGAAIQWLRDGIGVIKNYSETDDM
                     ANSISSTGGVYFVPAFAGIAAPYWDQYARGTMVGITGSTKKEHIVRATLESVALQVKD
                     VVDSMNLASGKKIKMLRVDGGITKNNFTMQFQSDILGIPIEIAENPETTVLGVGYMAG
                     LSCGVWNSIDEIRSEFTISKKYIPNMTTQKREEILLGWNQAVKRAMNWENDTKKVCAN
                     "
     gene            4115..5230
                     /locus_tag="OE968_002656"
     CDS             4115..5230
                     /locus_tag="OE968_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization protein EutH"
                     /protein_id="HCP7219928.1"
                     /translation="MPFDKIILYIMAVGVLLGALDRIIGNKFGLGEQFEEGFNSMGPL
                     ALGMVGIVCLAPVISDVLGPIIIPIFNLCGADPSMFATILANDMGGYPLAMELAHNKE
                     AGMLAGLVVSSMLGCTLVFSIPVGLGLIEYEDRPFFAKGLLIGLITIPFGGIIGGLIA
                     GFNLSMVIINMIPVIILAVILAVGLKFNSTLMINGSLVFGKFISILITIGLGAAAFQE
                     ITGIVLIKGMTPIREGIQVIGSIAIVLLGTFPILHLLVKVLNKPLTIVGGKLGMDATS
                     AAGLVFTLANSIPVYKMMKDMSPKGKVVNTAWLVCATAALGDHLGFTAGVVPEMITPV
                     VIGKLVGGVLAIALAILMTKDLTLEEEQSIKMKKDAV"
     gene            complement(5511..6275)
                     /locus_tag="OE968_002657"
     CDS             complement(5511..6275)
                     /locus_tag="OE968_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HCP7219929.1"
                     /translation="MLPQERYEKILSILKSDNIIKINDIVQMFDISIETARRDLAHME
                     SIGLLKRVYGGAIPVIASSVELNYVKRKKINSNDKKQIAIKCSEFINTNDTIFMDTGT
                     TVLEVSKNLKDKKNLTVITNSILVANELMNTNIKVYVLGGYLRETEGSFSGPLTLSAI
                     EQFNVDKAILGAGGITLENGISDYHLEEALVRKKMIERSRKSIVVVEPPKFGINSFAS
                     VAPIEHIDTIITSASIDHNIIIEFSQKGIPLVIADN"
     gene            6534..6624
                     /locus_tag="OE968_002658"
     tRNA            6534..6624
                     /locus_tag="OE968_002658"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:6568..6570,aa:Ser,seq:gct)
     gene            6712..7500
                     /locus_tag="OE968_002659"
     CDS             6712..7500
                     /locus_tag="OE968_002659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor protein"
                     /protein_id="HCP7219930.1"
                     /translation="MTTLIFFIVGIASLVVAFVIDGGHVGALFVFSSALVVFGGTIGA
                     VGASTPFPVFKKSIKIMLLTFKNKKPNNIENIIYFKEIATKARKEGLLSIDKEISEND
                     ELDPFIRKGLELMVDGVDAVTIRNILESQIQITSKRHKEGIAIFDSAGGYAPTLGIIG
                     TVMGLVHILGNLSSNPDALGPQISVAFLATLYGVGSANLIWLPIASKLKAINQQEVSE
                     RLLVIEAILSILEGDNSNLMTEKLKIFLNSKELIELEEIGGRAE"
     gene            7521..8261
                     /locus_tag="OE968_002660"
     CDS             7521..8261
                     /locus_tag="OE968_002660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HCP7219931.1"
                     /translation="MLYDEDEKEENNERWLLTYSDLITLLMIFFVIMYSMSNVDAEKY
                     KQLSQSLNSAFGGSSGVIEGGNSKIEPVVEPGSNDLDTLQNAKFKKIGEEIQKYLNEN
                     GMANSVSLRVQDRGLVISLKDTILFDTGKAIVKDNSRDKIIQIGKMLNEMNSYMRVEG
                     HTDNMSIKNSEFKSNWDLSVMRATNVVQLLIDNAGIAPDKLSAVGYGEFRPIAENSSE
                     EGRSKNRRVDIVLVDSKYDNVENVSKDK"
     gene            8437..8811
                     /locus_tag="OE968_002661"
     CDS             8437..8811
                     /locus_tag="OE968_002661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219932.1"
                     /translation="MGNKNKNTKYKDKTRERYNKKVENLNKEKLNKINKQSKKVDKID
                     DIINKSSIVLCVLLVVFSLLYLFKLVQLNIIMILLVITVAIQQGLVSFGAFRNKNYVK
                     ALFSIFVIVCFLIAFKYVVNPV"
     gene            8903..10363
                     /locus_tag="OE968_002662"
     CDS             8903..10363
                     /locus_tag="OE968_002662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HCP7219933.1"
                     /translation="MNRCKFAKLIITSMIVLLLTGCSLKKEDNYKLDPENPTSIQIWH
                     YYNGQQKMAFDKLVKEFNDTVGAEKGIIVEAFSQGNVVDLSEKVLDSANKKVGSEDVP
                     NIFAAYSDTAYEMDKLGLLVDMDKYISKEELNEYIDEYVEEGRINSKDEFKLFPIAKS
                     TEILMLNKTDWDKFAKATNSNINDIKTIEGLVETSKKYYEWTDSLTKEPNDGKAFFGR
                     DALANYIIIGSKQLGVEIFSVKDGKVTLNIDEKVMKKLWDNFYVPYINGYFASYGKFR
                     SDDAKTGDILALVGSSSGAAYFPDRVMLNDNESYNIETSVFQAPRFKGEGKYAVQQGA
                     GMAVTKSTKEEEYASVEFLKWFTDKEPNIKFSIASGYLPVKKKTNDLDVIKEVMKKDN
                     LSLSDKVEGSIASSIEQINSCNLYTNKAFDGGTKARQILEYSMLDKAKEDSNKINELV
                     KSGTSKKDAVAQFNNDKNFKTWFESFKAELENAIKK"
     gene            10416..13445
                     /locus_tag="OE968_002663"
     CDS             10416..13445
                     /locus_tag="OE968_002663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HCP7219934.1"
                     /translation="MENNLRKNNSIMKKMIFPLIIVMLIQTSLFCATILWGGTIKKLN
                     DNSFDILNERVINRKNYIQNEMLQRWSNTSETEATINSSVKKVLNEKNALIEDVGNNE
                     EINKDIIKSISNDLIYLLRKNSVTGAFIILSDKNINDKSIDSKGEISRTGLYIRDLDP
                     KFNPNDNSDLLIERGSSDIARSFGISMDSYWEPKFSFKSENEQDGDDFFYKPFRAAID
                     NPNVSSSNLGYWGSKFLLTNAGDRLMTYTVPLIYEDGTVYGVLGIDLSVNYLRELLPY
                     SEINGNKKGNYILGVDRNNDMAFENVISNGYSLKEKFWDGLHSNLEQKESYKNIYKIK
                     NKDNECGNGNIYASVQYLDLYNSNTPFENERWALLGIIEEKSLLSFSKRVEKLVIISI
                     AISLLIGLIGIYIASRLFTKPIVLLANKVRNSNPSKPVNLDKINISEIDELSSAIELL
                     SANVADSSSKLSQIIEMVDMPIGAFELYKNAENVFCTKEFFSVFTTEIKFEEYGYMEK
                     NKFLKKLRGLDKYLQESYETENTYIYKFESKDKKLKWIRMNIFEDELKVLGVVVDVTK
                     EFIEKRKIEYERDFDILTNLLNRRAFHSQIQEKFKNKDELKIAAFIMWDLDNLKYIND
                     TYGHDAGDEYIRCAADILKKFISWNGIVSRLSGDEFYVFIYGYESKDSIRDIINSVKK
                     QMNNTLLKLHDGTEFKIRASAGISWYPDDSTNYDELMRYADFAMYQIKNTIKGEVSEF
                     DINIYNKDSFLLSNREELNKLIDGQLVEYAFQPIVDCKGKVFAYEALMRPKIKTFSSP
                     IDVIRLARSQSKLYQIERITWFKALKSFKKYKEKFGDCKLFLNSIPNNNLSKVDFEEI
                     EDLYGEYLNRVVLEITENDKINEDFIEKKKAYIDHWNIEIALDDFGTGYNGDAVLLYI
                     MPDYVKIDMSIVRGIDKDENRQKILKNLISYSNERNIKVIAEGVETKGEMETLINLGV
                     DYMQGYYISKPSFIPEDISDKIKKELKICHENRNDVV"
     gene            13522..15588
                     /locus_tag="OE968_002664"
     CDS             13522..15588
                     /locus_tag="OE968_002664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HCP7219935.1"
                     /translation="MVELIITTNIDIRKLNENQLEAVEHIDGPCMILAGPGSGKTRVI
                     TYRIANMVVNKNIAPTRILAISFTKASSIEMKNRALNLSDDIRLNKVTYGTFHSVFFK
                     ILRYFERYNLDSIFDEKSKRMTIKAILKSLNIENADDDENIGQVINEISYVKNELMDK
                     NEFNSEVLTKDEFLKVYNLYEEQKSKVNKIDFDDMLIRTYYLLLNNKSALEMVRNVYK
                     YILIDEFQDINKVQFEVLKLICSPLNNIFAVGDEDQSIYGFRGARPDFLLEFEQYFNN
                     TKKIILDINYRSKSEIVHTANRLIDKNKNRYEKIIKCSQGDGGSVTYISPHDSEEEAL
                     YIAREIIDEIQKDYVEYSDFAVIYRTNIQSRALVDVFMDMRIPFVVKDSVITIYDHWA
                     SQDILAYLRIGINPKSNKDWLRIINKPFRYISKDSINMVKDEKDFITALINKCNLHPK
                     QVKTINDLEIDLSYLNTLNPKNAISYIRTSLDYDRYVLDYCSNRKIKTNGLVEILNEL
                     ESSATNFNTVTEFLEHIDRVKTELTENNKNKQTEGVIFTTMHSAKGLEFRNVYIIGVN
                     EGTIPHEKSYDICKEEKKEEQLEEERRLMYVAITRAEEKLCISSTLNKYGKKVDKSLF
                     INDIKSPTKKEIDSIGVGDKVYHKKFHEGEIIKKDGIMFTIKFKDRERILDLKTCLLK
                     NIIYTI"
     misc_binding    15971..16181
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            16407..17222
                     /locus_tag="OE968_002665"
     CDS             16407..17222
                     /locus_tag="OE968_002665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HCP7219936.1"
                     /translation="MKVFKKLLSLGLVLGLTLSLVGCSGGGEKTKLEQIKDNGKLVVG
                     TSAEFPPFEFHKVVDGKDSIKGFDIMLAEEFAKELGVKVEIKDMSFDGLIGALNADQV
                     DIVLAGMSPTPEREKSVDFSELYYLSRNAVIVKDADIDKVKTEDDLKKLRVGVQAGSI
                     QEEYVVNTLKMTTTKSLKAIPDLITELKNGNIDAVVTNEAVSLINVKKYDGIKMANTE
                     VGKDVTEGMAAAIKKSDNNKDFIELLNKKIKELQDGKKIEEFLNEASTEAASN"
     gene            17250..17927
                     /locus_tag="OE968_002666"
     CDS             17250..17927
                     /locus_tag="OE968_002666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HCP7219937.1"
                     /translation="MSLDFSFLSRFGTSFLEGTGVTVSISLVALCFGFIIGIIICMAK
                     ISKSKVLRAISSIYIEVLRGTPLLVQIYIVWFGLPQLGIRFPMLFGIPSEFIASAFAL
                     SVNSGAYVAEILRSGIQSVDNGQMEASRSLGLNYWSTMRYIIIPQAIKNILPSLANEF
                     ITLVKESSIISVIGVVEIMRTADIVKNAAFRALEPLIVAAAIYFVITFTLSRLVGLLE
                     KKLSVSN"
     gene            17986..18708
                     /locus_tag="OE968_002667"
     CDS             17986..18708
                     /locus_tag="OE968_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004398740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HCP7219938.1"
                     /translation="MITIKNLSKSFGDLNVLKNIDLEIAKGEIMVIVGPSGSGKSTLL
                     RCMNLLEIPTGGEIIFEGKNLVDKKTNIDEVRQNIGMVFQNFNLFPHKTILDNITLAP
                     IKLKKMTKEEAEKKAEILLSRVGLLDKKDSYPSQLSGGQKQRIAIARALAMEPDMMLF
                     DEPTSALDPEMVNEVLDVIKELAKEGMTMAIVTHEMGFAKEVADRVIFIDGGSILEDN
                     TPEEVFGNPKHERTKAFLAKVL"
BASE COUNT         7569 a         2011 c         3387 g         6136 t
ORIGIN      
        1 tttaaatcta taaatataga taaaatctaa ttatttaact tcaactattc ctcaaaaaag
       61 caacttttaa ggaatagttg aagcaaaaag tttggttaca taatagtaat tttagttaca
      121 agaatgaaac tgtaaaactt aggattttct ttatataatt tcattgagaa catttaattt
      181 aggaggtaag atatgaaagt aaaaaaattt aaaagtggta tagtaatggc attaacagta
      241 atggcaattg gagcatcatt gacaaatgta tcagctatgg aattaaacaa gagtaaagag
      301 tttgaaacta aatacaatga aatgaagatg gattttcaag aggaatatgg aaaagaagac
      361 aaatttaata taacattgga tgatgaattt acaaaagaag aagtaaatgg agctaaaggg
      421 attataaaga caactaataa aatgaataat gaggttgtag tattaaatta ttttgatgaa
      481 atgaaatctg gaattgaatt tgagttgaag ccaaaagcag aaaaaaatgc aattttgaga
      541 gatgaatttc aacaaggtta tggaaaggaa gataaattca aagttgtgtt agatgatgaa
      601 tttacaaaag aagaggtaaa tggagctaag ggcattataa agactacaga taaagagaca
      661 ggtgaggtta tcgtatataa ttactttgat gagcttgaaa aataatgctt aaagattact
      721 ttgattgaat gaaaaggtaa ttgtgttgag aatataaaat gactgaataa aaacagttgt
      781 atcaaaacaa acaataatag aatgtaagaa tgattgtgtt gaaaatatta aatgactgaa
      841 taaaaaacga ttgtgtcaaa aataaaaaat aattaagtgt aagaatgatt gtatcaagaa
      901 tataaaatga ctgaataaaa aacgattgcg tcaaaaataa aaaacaatta aatgtaagaa
      961 taattatgtc aaaaatataa aataaattaa aagaaaaaga ttatattgaa ggaaaaagat
     1021 ttgaaatagg ggtgaacttt acatattata gttcaccctt atacaaaaat ataaaatata
     1081 atttattata ggaaaattta aaaaaatcag tctatttaat ttatactgat atattgtagg
     1141 attttacaaa caaactgtta tataactttt tttatctcca attttgattt taagatatct
     1201 aagaatttat aacaatcttc tggatatatt tctcccatat ttgctacttg gaatatatta
     1261 gcatctagga atttaccttt tcctggatag acaacatagc cactttccct ttctagccct
     1321 aatataaact catttacatt gatttcttta ggtagaaata cagatgttac tgtattagac
     1381 atatacttat ctggaagtaa aaatgttaga cccaattctt ccataccatt ccttaaaata
     1441 gcagaacatt ctttgtatct ttctatttta ctgtcatctt ccaaaaactc agttaaagct
     1501 tcattaaggg caaatattaa agtaacatta ggtgtatttg gtgtttgaga agatgattta
     1561 gcaactttat agtgtttata aagattaaga tacacattct tacattgatt ttctttaata
     1621 ttttgtaaaa tactctcttt agcacaaagg tatgcagaac ctggaaatgc tccaagagct
     1681 ttgccaccaa cacctgttat tatatctata ttaaactctt ccacatcaat atattcacct
     1741 gctgaggcac ttattgcatc tacaaaaaat attttgttat acttcttagc aagttttcct
     1801 agttcaggga ctggatttat cattcctgaa ctagtttcat ggaacaccat agcaattact
     1861 tttatatcag aattttcaat tatgtatttt tctaaaatgt ctaggtccgg gtattctgcc
     1921 cattcaaaat taggtttata tgtttttaca ttataagtag ataatatttc ttctagcctt
     1981 tctccaaaaa caccattact aactagcaga actgcatctt ctttgtcaaa gatagaagat
     2041 agtacacatt catttacaga tgttccagag ccagatacaa ttaatgagta gtaattagaa
     2101 gttgcattat atagtttatt gattttttgt tgtgtatctt tgaataaatc cataaactca
     2161 tttcctctat ggcatatatc atagtgaaga agtgaatttc tgactttatc tgtaaccatt
     2221 actggtccag gactgaatag atatgttttt ttcattgtaa agcctcctta aaaagttaaa
     2281 tttaaatttt tgaatgactg attatgtgta aatattaaaa tattatgtgt tattttaact
     2341 agattataga ataaaataat aaatattgca ataatatttc aataaaaata cttttttaat
     2401 cactataatt aaaaataaca aaaaatattg taatgaatat tgcataaatc cacatgatga
     2461 tataaaatat aaataacttg aatagattat atattcaaaa aataaaaaag aatttattaa
     2521 ttctgaaaat aaagggggac atttaaagtg aaatatgtat tagcaattga ccaaggaaca
     2581 acaggaacaa gagcagtatt gataaacgaa aaatcagagt ttgtttttag cgattatatg
     2641 gaacatactc aaatatatcc acaatctgga tatgttgaac atgaccctat agaaatttgg
     2701 aataatacaa aaactgtgag taataatgta ttacaacagg cttttgaaaa tggaatcaat
     2761 gaaagtgata taaaaggaat tggtatagat aatcaaggtg aaacagtaat gttatgggat
     2821 aaaaatacag gtaaaccact ttacaatgct attgtgtggc agtgcaggag aacttatgat
     2881 tatgtggaaa atttaaagaa tataccaggt ttagaaaata agataataga taagactggg
     2941 ttaattatag acccatattt ctcaggtaca aaaattaaat gggtaataga taatgtaaaa
     3001 ggtgtaaaag aaaaaattaa aaatggagaa gtacttgcag gaacattaga tagttggtta
     3061 atatggaaaa tgacaggagg aaaatctttt ttaactgatg tatctacagc agcaagaaca
     3121 atgcttttta atataagaga tatggattgg gatagagagt tgcttgacat tataggagta
     3181 cctagaagta ttttagcaga tataatgcct acgagtggtg attttggaac tacagataag
     3241 gaggcatttt gtggggtttc tataaaaatt actgcttcaa tggtagacca accagcagct
     3301 ttatttggca atggatgttt tgaaccagga atggttaaaa atacttatgg tacaggatgt
     3361 ttcctatata tgaatatagg tgaggaacta aatatagcag gtaatggtat tttgacaact
     3421 gttgcttgga aaataggaga taaagttaca tatgcttatg atggtggagt gtatatagca
     3481 ggtgctgcaa tacaatggct tagagatggc attggagtta taaaaaatta ttcagaaact
     3541 gatgacatgg caaattccat atcaagtact ggaggtgtat attttgtacc agcatttgca
     3601 ggtatagcag caccttattg ggaccaatat gctagaggta caatggttgg aataacagga
     3661 agtactaaaa aagagcatat agtaagagcg actcttgagt ctgttgcact tcaagtcaaa
     3721 gatgttgttg attctatgaa cttagcctca gggaaaaaaa taaaaatgtt gagagtagat
     3781 ggtggaatta ctaaaaataa ctttacaatg caatttcaat ccgacatatt aggtatacca
     3841 attgaaattg cagaaaatcc tgagacgaca gtacttggag taggatatat ggcaggtctt
     3901 tcttgtggtg tctggaacag tattgatgaa attagaagtg aatttacaat aagcaaaaaa
     3961 tatattccaa atatgactac tcaaaaaaga gaagaaatat tacttggatg gaaccaagca
     4021 gtaaaaagag ctatgaattg ggaaaacgat accaaaaagg tgtgtgctaa ttaagttaca
     4081 atagagtatt ttacatgtat aggaggaatt aaaaatgccc tttgataaaa ttatattata
     4141 cataatggct gtgggagtgc ttttaggagc gttagataga ataattggaa ataaatttgg
     4201 acttggcgag cagtttgaag aagggtttaa ttcaatgggt ccattggctt taggaatggt
     4261 tggtatagtt tgtttagctc cagtaatttc agatgtacta ggtcctataa taataccaat
     4321 cttcaatctc tgtggagctg acccatctat gtttgcaact attttagcga atgatatggg
     4381 agggtatcca ttggctatgg aacttgcaca caataaagag gcaggaatgc ttgcaggatt
     4441 ggttgtgtca tccatgcttg gatgtacatt agtattttca attccagtag gactaggtct
     4501 tatagaatat gaagacagac cattctttgc aaaagggtta ctgataggct tgataacaat
     4561 accttttgga ggtattatag gaggattaat agcaggattt aacttatcaa tggtaattat
     4621 aaatatgata ccagtgataa tattggcagt aatattggca gtaggtttaa aatttaattc
     4681 tacgcttatg ataaatgggt cattagtttt tggaaaattt atatctatat tgataacgat
     4741 aggtttggga gcagcagcat ttcaagaaat aacaggtata gtacttataa aaggcatgac
     4801 acctataaga gaaggtattc aagtaattgg aagtattgca atcgtgttat taggtacttt
     4861 tccaatatta catttattag ttaaagttct taataaacca cttacaatag tgggtggaaa
     4921 attaggtatg gatgccacta gtgcagcagg attagttttt actttagcca atagtattcc
     4981 agtatataaa atgatgaaag atatgagtcc aaaggggaaa gtagtaaata ctgcttggct
     5041 ggtttgtgct acagcagctt tgggggacca tttaggattt acagcaggag tagttccaga
     5101 gatgattaca cctgttgtaa ttggaaaatt ggttggagga gtattggcaa ttgcacttgc
     5161 tatacttatg acaaaagatt taaccttgga agaagaacaa agtattaaaa tgaagaaaga
     5221 tgcagtgtag aataaacaat acttaagtca aatttaaatt attttaaagt aggagtttaa
     5281 ataactaaaa ataaattaaa aagacagaca attaaaaaat aatcgaataa ctaaaactta
     5341 taaattaaat aaaatggcaa tcaaataact aaaaatgata agctaactga aagtagttac
     5401 ataattaaaa tataaagtat agtttagaca taaatggagc taaataaata attatttggc
     5461 tccttaattt taatttatta catcaaggaa ctaaaaatca atcatataag ctaattatca
     5521 gctatgacta aaggtattcc tttttgagaa aactctatta ttatattatg gtctatacta
     5581 gcagaggtaa taatagtatc tatatgttct ataggagcta ctgatgcaaa tgaatttata
     5641 ccaaacttag gaggttcgac aactactata gattttctag acctttcaat catttttttt
     5701 ctaacaagtg cttcttctaa gtgatagtca gagattccat tttcaagagt gatacctcca
     5761 gcgcctaaaa tagctttatc aacattaaat tgttcaatag ctgacagtgt aagcggacca
     5821 gaaaaagaac cttcagtttc tctaagatag cccccaagca catatacttt tatattagta
     5881 ttcataagct cgtttgcaac taaaattgag ttggttatta cagttagatt ctttttatct
     5941 ttcaaatttt ttgaaacttc aagtacagta gttccagtat ccataaaaat agtatcattt
     6001 gtatttataa actcactaca tttaatagca atctgttttt tatcgtttga gtttattttt
     6061 tttcttttaa catagttaag ttctacgcta cttgctataa ctggtatagc accaccataa
     6121 actcttttta aaagaccgat actctccata tgggctaaat ctcttcgtgc agtttctatt
     6181 gatatatcaa acatttgaac tatgtcattt attttaatta tattatctga tttgagaata
     6241 cttaaaatct tctcatatct ttcctgtggt aacataaaat atcctccttg gactagtatt
     6301 attttagttt tggcataact tacaattaag tcagagttta ggtatatttg ttaatgtatg
     6361 tatatttatc aaataatatt ataagtgtta tgcaagataa ttttaccata tttaaaactt
     6421 acatttaagc aaaaaagtaa aaatagatgt ttaataattc aaaataactc aaattttata
     6481 aaacaattga ctaaaatatg attttattat ataatttact agtatagaga tatggagaag
     6541 tactcaagtg gctcaagagg atcccctgct aagggattag gctgggtaac cggtgcgagg
     6601 gttcgaatcc ctccttctcc gccaattatt aaaggctatt tttattaaag atagtctttt
     6661 tataatgtca taaatgatta gatatgtata actaaagaaa ggagggaata gatgacaact
     6721 ttaatttttt tcatagtggg gatagcatct ttggtagttg cttttgttat tgatggggga
     6781 catgttggag cattatttgt attttcatca gcacttgttg tgtttggtgg aactatagga
     6841 gctgttggag cttcgactcc attccctgtg tttaaaaagt ctataaagat aatgttatta
     6901 acttttaaaa ataaaaagcc taataacata gaaaatataa tctatttcaa agaaattgca
     6961 acaaaggcta ggaaagaggg gcttcttagt attgacaaag aaataagtga gaatgatgaa
     7021 ttagaccctt ttattagaaa agggcttgaa cttatggtag atggagtgga tgcagttact
     7081 ataagaaata tattggaatc acagatacag ataacatcaa aacgacataa agaaggaata
     7141 gcaatttttg attcagcagg tggatatgca cctacactgg ggataatagg tacagttatg
     7201 ggattagtac atattttagg taatctttca agtaatccag atgcattagg acctcaaatt
     7261 tctgttgcat ttttggctac tttgtatggt gttggttctg ccaatttaat atggttacca
     7321 atagcatcaa aacttaaggc tataaatcaa caagaagtaa gtgaaagact tttggtgata
     7381 gaagcaatat tatccatact tgagggtgat aattctaatt taatgacaga aaaattaaaa
     7441 atatttttaa attcaaaaga actaattgaa cttgaagaaa ttggtggtag agctgaataa
     7501 tataaaagga tggaatgttt atgttgtatg atgaagatga aaaagaagaa aacaatgagc
     7561 gatggctttt aacttattca gacctcataa cattacttat gattttcttt gtaataatgt
     7621 attctatgag taatgttgat gcggagaaat ataaacaatt atctcaatct ctaaattctg
     7681 cttttggtgg ttcttctgga gttattgaag gtggtaatag caagatagaa ccagtagttg
     7741 aaccaggaag taatgattta gatactttac aaaatgctaa gtttaaaaaa attggtgaag
     7801 aaattcagaa gtatttaaac gaaaatggta tggctaattc agtatcatta agagttcaag
     7861 atagaggatt agtaataagc cttaaagata caatactatt tgatacaggg aaagctattg
     7921 tgaaggataa ttctagagat aagattattc aaataggtaa gatgttaaat gaaatgaata
     7981 gttacatgag agtagaaggc catacagaca atatgtctat aaaaaattca gagtttaagt
     8041 caaattggga tttatcagtt atgagagcaa ccaatgttgt tcaacttctt attgacaatg
     8101 caggtatagc accagataaa ttatctgctg taggatatgg tgagtttaga ccaatagcag
     8161 aaaattcatc tgaagaaggt aggtcaaaaa atagaagagt tgatatagtt ttagttgata
     8221 gtaaatatga taatgtagaa aatgtttcaa aggataaata gttaaattag ctgtctcaat
     8281 acagaattaa ttctaaagga gatggctttt ttatgcgaaa atcaaaaata gatacatagt
     8341 aagttacctt tttgtaggaa tatatggtat cttaaatata taatatttaa ataatgtata
     8401 agctcaatta aaaaatttat agaggatgga aaataaatgg gaaataaaaa taaaaatact
     8461 aaatataaag ataaaacaag agaaaggtat aataaaaaag ttgagaattt aaataaagaa
     8521 aaattaaata aaattaataa gcaatctaag aaagtagata agattgatga tattattaat
     8581 aaatctagta ttgtattatg tgtacttcta gtagtgtttt cattgcttta cttatttaaa
     8641 ctggttcaac ttaatataat aatgatactt ttagtaatta cagtagctat tcaacaagga
     8701 ttggtgtcat ttggtgcatt tagaaataaa aattatgtaa aagctttatt ttctatattt
     8761 gtaatagtat gtttcttaat tgcttttaaa tatgttgtaa atcctgttta aatatatcaa
     8821 taaacgttct ataattaata taaatagtga agttacagtt ttaatgctat tataaatttt
     8881 ataatttgaa ggagtagatt ttatgaatag gtgtaagttt gcaaaattaa ttatcacatc
     8941 aatgattgtt ttattactta caggatgtag tttaaagaag gaagataatt ataagttaga
     9001 cccagaaaat ccgacatcaa tacaaatttg gcattattat aatggacagc agaaaatggc
     9061 ttttgataag cttgttaagg aatttaatga cactgtaggt gctgaaaaag gaattattgt
     9121 tgaagcattc agtcaaggta atgtagttga tttatcagag aaagttttag attctgcaaa
     9181 taaaaaagtt ggttctgaag atgtaccaaa tatatttgca gcatactcag atactgcata
     9241 tgaaatggat aaattagggt tactagtaga tatggataag tacataagta aagaagaatt
     9301 aaatgaatac atagacgaat atgtagaaga aggcagaata aattctaagg atgagtttaa
     9361 acttttccca attgcaaaat caactgaaat tttgatgtta aataaaactg attgggataa
     9421 atttgcaaaa gctacaaatt caaatataaa tgatataaaa acaattgaag gattagtaga
     9481 gacatcaaaa aaatattatg aatggacaga tagtttaacg aaagagccta atgatggtaa
     9541 agcatttttt ggaagagatg ctttagcaaa ttatattatt ataggaagta aacaactagg
     9601 agtagaaatt ttttctgtta aagatggtaa agttacacta aatattgatg aaaaagttat
     9661 gaaaaaacta tgggataatt tctatgtacc atatataaat ggatattttg cttcttatgg
     9721 taagtttcgt tctgatgatg caaaaacagg tgatatatta gctcttgtag gttctagttc
     9781 aggagcagca tactttccag atagagtaat gctaaatgat aatgagagtt ataatattga
     9841 aacatctgtt tttcaagcac cacgttttaa aggagaagga aaatatgctg tacaacaagg
     9901 tgcaggaatg gctgtaacaa aatctactaa agaagaagaa tatgcatcag tagaattttt
     9961 aaaatggttt acagataaag aacctaatat aaaattctct attgcttctg gatacttacc
    10021 agtaaagaaa aaaacgaatg atttggatgt tataaaagaa gttatgaaga aagataattt
    10081 gagtttatct gataaagttg aaggttcaat agcctcatct attgaacaga ttaacagttg
    10141 taatttatat actaataaag catttgatgg tggaactaaa gctagacaaa tacttgaata
    10201 ttcaatgctt gataaagcta aagaagattc aaataaaata aatgaattag taaaaagtgg
    10261 aacttctaag aaggatgcag tagcacaatt taataatgat aaaaatttta aaacttggtt
    10321 tgaaagtttt aaggctgagc ttgaaaatgc tataaaaaaa tagatgaatt ggcagttagt
    10381 gtgttgacga gcacaaaggt ataggtggaa tgggtatgga aaacaatcta agaaaaaaca
    10441 attcaataat gaaaaagatg atatttcccc taattattgt tatgctaatt caaacaagtt
    10501 tattttgtgc cacaatttta tggggaggaa ctattaagaa attaaatgat aattcgtttg
    10561 acatcttaaa tgaaagagta attaatcgta aaaattatat acaaaatgaa atgttacaaa
    10621 gatggtcaaa tacaagtgaa acggaagcta caattaattc ctctgtaaaa aaagtattaa
    10681 atgaaaaaaa tgccttaatt gaggatgtag gcaacaatga agaaattaac aaagatatta
    10741 taaaaagcat atcaaatgat ttaatatatc ttttgagaaa aaattctgtt acaggagctt
    10801 ttataatcct aagtgacaaa aatattaacg ataagtcaat agatagtaaa ggtgaaataa
    10861 gtaggacagg attgtatata agggatttag accctaagtt taatccaaat gataattctg
    10921 atttgttaat tgagagaggt tcatcagata tagcaagaag ttttggaata tctatggaca
    10981 gttattggga acctaagttt tcatttaaaa gtgaaaatga gcaagatgga gatgattttt
    11041 tttataaacc atttagagct gcaattgata atccaaatgt atcaagttct aatttaggat
    11101 actggggaag taagttttta ttgacaaatg caggtgatag gcttatgaca tatacagttc
    11161 cccttattta tgaagatgga actgtatatg gagtacttgg aatagattta agtgtaaatt
    11221 atttaagaga attacttcca tactcagaga taaatggaaa taaaaagggt aattatattt
    11281 taggtgtaga tagaaataat gatatggcct ttgaaaatgt aatttcaaat ggatactcat
    11341 taaaagaaaa attttgggat ggtttacatt ctaatttaga gcagaaggaa tcgtataaaa
    11401 atatatataa gattaaaaat aaagataatg aatgtggtaa tggcaacatt tatgctagtg
    11461 tacaatactt ggatttatat aactccaata ctccatttga aaatgaacgt tgggctcttt
    11521 tgggtattat tgaagaaaaa agtcttttgt cattttcaaa aagggtagag aaattagtta
    11581 taatatctat agcaatttct ttattaatag gtctaatagg tatttacatt gcatcaagat
    11641 tatttacaaa accaattgtt cttttagcca acaaagttag aaacagtaat ccatcaaaac
    11701 cagtaaatct tgataagata aatatatctg aaatagatga attatcttca gctatagagt
    11761 tgctcagtgc aaatgttgca gattcttcgt caaaattatc acagattatt gaaatggtag
    11821 atatgccaat tggggctttt gagttataca aaaacgcaga gaatgttttt tgtacaaaag
    11881 aattttttag cgtgtttact actgaaatca aatttgaaga atatggatat atggaaaaaa
    11941 ataagttcct gaaaaaatta aggggactag ataaatattt gcaagaaagt tatgaaacag
    12001 aaaatacata tatatataag tttgaatcta aagataaaaa acttaagtgg ataagaatga
    12061 atatctttga agatgagcta aaggttcttg gtgttgttgt tgatgtcaca aaagaattta
    12121 ttgagaaaag gaagatagaa tatgaaagag attttgatat tttaacgaat cttttaaata
    12181 ggagagcttt tcattcacag atacaagaaa aatttaagaa taaagatgaa cttaagatag
    12241 cagcatttat tatgtgggat ttagataatc taaaatatat taatgataca tatggacatg
    12301 atgctggtga tgaatatatt aggtgtgctg cagacatact taagaagttt atatcatgga
    12361 atggtatagt atctagactt tcaggtgatg agttttatgt atttatatat ggatatgaaa
    12421 gcaaagatag tataagagat attattaatt ctgttaagaa acagatgaat aataccttat
    12481 taaaacttca tgatggaaca gaatttaaaa taagggcatc agcaggaatt tcctggtacc
    12541 ctgatgactc aaccaactat gatgaattaa tgagatacgc agattttgct atgtatcaaa
    12601 ttaaaaatac aatcaagggt gaagttagtg aatttgatat taatatatat aataaggatt
    12661 cattcttatt gagtaataga gaagaattaa acaagttaat tgatggtcaa ttagttgagt
    12721 atgcatttca gcctattgta gattgtaaag gtaaagtatt tgcatatgaa gcacttatga
    12781 gacctaaaat aaaaactttt agttcaccaa tagatgtcat tagattagct cgttcacagt
    12841 ctaaattata tcaaattgag cgtattacat ggtttaaagc acttaaatca tttaaaaaat
    12901 acaaagaaaa atttggcgat tgcaaattgt tcttaaattc tattcctaat aataatttgt
    12961 caaaagtaga ttttgaggaa attgaagatt tatatggtga atatttaaat agagtagtac
    13021 tagaaataac agagaatgat aagattaatg aagattttat tgaaaaaaag aaagcatata
    13081 tagaccattg gaatatagaa attgctttag atgattttgg gacaggttac aacggagatg
    13141 ctgtactatt atatataatg ccagactatg taaagattga tatgtctatt gtaagaggta
    13201 ttgataaaga tgaaaacaga cagaaaatat taaaaaatct tatctcatat tctaacgaaa
    13261 gaaatattaa agtgatagca gaaggtgtag aaacaaaagg tgaaatggaa acactaatta
    13321 atcttggagt agattatatg caaggctact atattagtaa accatcattt atacctgaag
    13381 atataagcga caaaattaaa aaagaactca agatatgtca tgaaaatagg aatgatgtgg
    13441 tttaatagag gaaaaattaa atttattttt atgaactttt agtttataat taaaaagaaa
    13501 ataatataat tataaatcaa ggtggtggag ctaataatca caacaaatat agatataaga
    13561 aagttaaatg aaaatcaatt agaagcagtt gagcatatag atgggccttg catgatactt
    13621 gcagggcctg gttcaggtaa gaccagagta attacatata gaatagccaa tatggttgta
    13681 aacaaaaaca tagcaccaac aagaatcttg gcaataagtt ttaccaaggc atcttcaata
    13741 gaaatgaaaa atagagcttt gaatttaagt gatgacataa gacttaataa ggtaacctat
    13801 ggtacttttc actctgtatt ttttaaaatt ctaagatact ttgaaagata caacttagac
    13861 agtatatttg atgaaaagtc aaagcgaatg acaatcaagg caatcctaaa aagtttaaat
    13921 atagagaatg ctgatgatga tgagaatata ggacaagtta taaatgaaat ttcctatgta
    13981 aaaaatgaac ttatggataa aaatgaattt aattcagaag tattaacaaa agatgagttt
    14041 ttaaaagtat acaacttata cgaagaacaa aaatctaaag ttaataaaat agattttgat
    14101 gatatgctta taagaactta ttatttactt ttgaacaata agtctgcact agaaatggtt
    14161 agaaatgtgt ataaatatat attgatagat gaatttcaag atataaataa agtacagttt
    14221 gaagttttaa agttaatttg tagcccatta aacaatatat ttgcagttgg agatgaagac
    14281 caaagtatat atggatttag aggtgctaga ccagattttt tgcttgaatt tgaacaatac
    14341 tttaataata ctaaaaaaat aatattagat ataaattaca ggtctaaaag tgagatagtg
    14401 catactgcaa atagacttat cgacaaaaat aaaaatagat atgaaaaaat cattaagtgt
    14461 agtcaggggg atggaggaag tgttacctat atttctccac atgattcaga ggaagaagcc
    14521 ttatatattg ccagggaaat aattgacgaa atacaaaaag attatgtaga gtattcagat
    14581 tttgcagtaa tttatagaac taatatacag tcaagagcat tagtagatgt atttatggat
    14641 atgaggattc catttgtagt aaaagactca gtaattacaa tatatgacca ttgggcaagt
    14701 caagatatac tagcctattt aagaataggt attaatccaa aatcaaataa agattggttg
    14761 agaattataa acaagccttt tagatatata tccaaagaca gtataaatat ggttaaggat
    14821 gaaaaagact ttataacagc attaataaat aagtgtaatc ttcatcctaa acaagttaaa
    14881 acaataaatg atttggaaat agatttaagt tatttaaata ctttaaatcc taaaaatgca
    14941 atatcttata ttagaactag tcttgattat gatagatatg ttttagatta ttgtagcaac
    15001 agaaagataa agactaatgg acttgtagag atattaaatg aacttgagag ttcagcaact
    15061 aattttaata ctgttacaga gtttttagag catattgata gagtaaagac tgagttaacg
    15121 gaaaataaca agaataagca gactgagggt gtcatattta caactatgca tagtgcaaaa
    15181 ggattagaat ttagaaatgt ttatattata ggtgtaaatg aaggaacaat acctcatgaa
    15241 aaatcatatg atatttgtaa ggaagagaaa aaagaagaac aattagaaga agaaagaaga
    15301 cttatgtatg ttgctattac aagagctgaa gaaaagttat gtataagctc tactttaaat
    15361 aagtatggta agaaagttga taaatcatta tttattaatg atataaaatc tccaacgaaa
    15421 aaagaaattg acagtattgg tgtaggggat aaggtatacc ataaaaaatt tcatgaagga
    15481 gaaataatta aaaaagatgg aattatgttt acaataaagt ttaaagatag agagcgaatc
    15541 ttggatttga aaacttgttt attgaagaat ataatttata ctatttaatt tagaatctaa
    15601 atttagatag aaatataatg tattatttat tatgtgcaag acaaatagat atgtgtaaaa
    15661 tgtattattt aacttattag aaaaagaaat aagggtttaa tatattattt atagttgttt
    15721 agaaaaagca acaatgtgga aaatattatt tagtattatt aaagaaaagc aacaatgtga
    15781 aagatattat ttagtattat ttaagaaata gctaaaaata tgaaatatac tatttataat
    15841 tacacaaata atatcaataa atataaacag tagtatttag ataatttaca agtaaaaatt
    15901 attaaaaaaa taaaaaactt attgacaaaa atattataag gaagtacaat tgtattaaca
    15961 atttaaggaa acaaatccaa tgatagagaa agtagcatat atggatttac agcgagttag
    16021 gggttggtgt aagcctaaca atgaagtcta tgtgaagaga gctctggagg agattatcag
    16081 aaactttagt atgataattg gtttacccgc cttaagggat tgagaggata agtacttact
    16141 tatcaaaaag agtggtaacg cggatataat tcgtctctta gctgtaaagc taagggactt
    16201 ttttgatttt aaaataaaaa tatccataca gcttaaaagc taacagtcac aaattttgaa
    16261 agtaatataa gtatttatca ataagagtgg taacgcggta aagtcgtctc ttagtcatta
    16321 aagactgaga gacttttttt gtaactcgaa acatttaagt attaaaatct gagggaaatt
    16381 ataattaaaa gagaggggta gttaaaatga aagtatttaa aaaattatta agtttaggat
    16441 tagtattagg attgacatta tcgctagtag gatgtagtgg tggaggagaa aaaacaaagt
    16501 tagaacaaat aaaagacaat ggaaaattag ttgttggtac tagtgcagaa tttcctccat
    16561 ttgaatttca taaggtagta gatggaaaag attcaataaa aggattcgat ataatgttgg
    16621 ctgaagaatt tgcaaaagag cttggtgtaa aggttgaaat taaggatatg tcatttgatg
    16681 gattaatagg tgctttaaat gcagaccaag ttgatattgt tcttgcaggt atgtctccaa
    16741 caccagagag agaaaagagt gttgattttt cagaattata ttatttaagt agaaatgcag
    16801 ttatagttaa agatgcagat atagacaaag taaaaactga agatgattta aagaaactta
    16861 gagttggagt tcaagcagga agtatccaag aagaatatgt agttaacact ttaaaaatga
    16921 caactacaaa atctttgaaa gcaatacctg atttaattac agaattaaaa aatggaaaca
    16981 tagatgcagt tgttactaat gaagcagttt ctttaataaa tgttaaaaaa tatgatggaa
    17041 taaaaatggc aaatactgaa gttgggaaag atgtaacaga aggtatggca gcagcaatca
    17101 aaaaatctga caataacaaa gattttatag aattattaaa caaaaagata aaagaattac
    17161 aagatggcaa gaagatagaa gaatttttaa atgaagcatc tactgaagct gcttcaaatt
    17221 agtaagaaag ttatgtggga gatgaaatta tgagtttaga ttttagtttt ttaagtagat
    17281 ttgggacttc ttttttggaa ggaacaggtg tgacagtatc aatttctctt gtggcattat
    17341 gctttggatt tataataggt ataattatct gtatggcaaa aatatcaaag agcaaagtat
    17401 taagagcaat atcatcaatc tatattgagg ttttaagagg gacaccatta ttagtacaga
    17461 tatatatagt atggtttggt ttacctcaat taggaataag attccctatg ttgtttggta
    17521 taccaagtga atttatagct agtgcatttg cattatcagt aaactctggt gcatacgtgg
    17581 cagagatact tagatcaggt atacaatcag ttgataatgg acaaatggaa gcaagtagat
    17641 cattaggatt aaattattgg tcaactatga gatatataat aatacctcaa gctataaaaa
    17701 atatattacc ttcattagca aatgagttta ttacacttgt aaaagaatct tcaataatat
    17761 ctgtaatagg agttgttgag ataatgcgta ctgctgatat agtaaaaaat gcagcattta
    17821 gagcattaga gccattaata gtagcagcag caatttactt tgttataaca tttactctat
    17881 caagattagt tggattatta gaaaagaaac tatctgtgtc taactagatg agagcatgtt
    17941 tagcatttag ggaaaacata gaatagtaaa aaggaaagtg ataatatgat tacaataaaa
    18001 aatttaagta aatcttttgg agatttaaat gtattaaaaa atatagactt agaaatcgct
    18061 aaaggcgaaa taatggttat agtaggtcca agtggttctg gtaaaagtac acttcttaga
    18121 tgtatgaatt tactagaaat acctacaggt ggagaaataa tatttgaagg aaaaaatttg
    18181 gtcgataaaa aaactaatat tgatgaggtt agacaaaata taggtatggt gtttcagaac
    18241 tttaatttat tcccacataa gactatttta gataatataa cattagcacc aattaaatta
    18301 aaaaagatga ctaaggaaga agcagaaaaa aaagcagaaa ttttgttgag tagagttggt
    18361 cttttagata aaaaagattc atatccatca caattatctg gaggacaaaa gcaaagaata
    18421 gcaatagcta gagcacttgc tatggaacca gatatgatgt tgtttgatga gccaacatct
    18481 gctcttgacc cagaaatggt aaacgaagtt ttggatgtta taaaagaact tgctaaagaa
    18541 ggtatgacaa tggcaattgt aactcatgag atgggatttg ctaaggaagt tgcagataga
    18601 gttattttta tagatggagg aagtatactt gaagataata ctccagaaga agttttcgga
    18661 aatccaaaac atgaaagaac aaaagcgttt ttagcaaaag tgctataata tataaaaagg
    18721 atgttattga tattagaaat tcaatacatc cttttttagt gatggttaat attaatttta
    18781 aaattaaagt tatattaata ttaactttat ttttacgatt ttttgcagaa aaaaaaagag
    18841 ctcggggtaa gctctttttt tccaccgaat taatttccgt tactaatccg atttttaata
    18901 aatataaaat atatccttat gaaagggtat tgggaataga tatattaact aactagggtt
    18961 accaggggga taaccttaat ttattataac aaaatgcgac acaaaaatca atattttttt
    19021 tgaaataaat tataaaagtt atttttataa caagtaagct tataaattta acttttatag
    19081 taaaaataag tatatgtata ata
//
LOCUS       DAJMZY010000080        19042 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.080, whole genome shotgun sequence.
ACCESSION   DAJMZY010000080 DAJMZY010000000
VERSION     DAJMZY010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 19042)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19042)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19042
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.080"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            101..334
                     /locus_tag="OE968_002668"
     CDS             101..334
                     /locus_tag="OE968_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219939.1"
                     /translation="MPQVKKLNRILTIEECKIDDFLEMGYDLIDETGKAVKYGKSLSV
                     KDLIAENNILRSKVESLEEENKQLKEKNKLTKK"
     gene            344..745
                     /locus_tag="OE968_002669"
     CDS             344..745
                     /locus_tag="OE968_002669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219940.1"
                     /translation="MENNIIDEIEKRLESFGYILKDGDKWLIGFVREKIENIIKLDCN
                     IKTMPIELKEIEVDMIVGEFLFTKKNMGQLDIESINFEAVEKSISEGDTKVDFAIGSG
                     SQTPEQRFDSLIAYLTTYGKNKILTFRCLRW"
     gene            739..1086
                     /locus_tag="OE968_002670"
     CDS             739..1086
                     /locus_tag="OE968_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219941.1"
                     /translation="MVSKTRKAIEMLYRDKCTIVEYQPIKDPVTKRTNNKEVIVLENQ
                     PCKLSYKNIVSATEGKVAKLEQTIKLFISPDIEIKAGSKLIINDKEYVRSGESAIYPN
                     HQEIILELFKDKA"
     gene            1086..1376
                     /locus_tag="OE968_002671"
     CDS             1086..1376
                     /locus_tag="OE968_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HCP7219942.1"
                     /translation="MARWGSVDFREFKRVCKKMEELTKIDLDKFCKDAARELAARLLG
                     KVIRRTPVDTGFLRQGWNGVAYARSLPVYKQGNNYIIEVVNPTEYALTQWGI"
     gene            1486..2292
                     /locus_tag="OE968_002672"
     CDS             1486..2292
                     /locus_tag="OE968_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219943.1"
                     /translation="MAKFLDITGKKFGRLRVIKFSKEIKSGKRNRKYWLCKCDCGNFK
                     EIRTDSLTSGLVQSCGCLKKEQDKLNLTDKYQFKKKYKVQNKRLYSIWKGIISRCTDK
                     NNKRYNRYGERNIIVCDEWFCYDNFANWALSNGYSEKLTIDRINNEGNYESSNCRWVD
                     IKTQCRNRSTNILVKHEEKEITLIELSEKTGISYSCLRSRYSKGLVGNNLIEKVKIIE
                     ESRAKLSIEDVKEIRKKYSDGYTIKQLSEIYPVTYSSISNIVHRRTWKNI"
     gene            2641..3078
                     /locus_tag="OE968_002673"
     CDS             2641..3078
                     /locus_tag="OE968_002673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219944.1"
                     /translation="MLNNIIDGISIKLDKTFGESYTIYSEDVEQGINEPCFFIVPLNP
                     SKVSYPSGRTLKKNSFDVHYFPKSNDKSFEIDEVAEMLLEELEYIEIDGDLVRGTNMN
                     FEIVDNVLHFFVDYNYFTIKNNDINKMDTVELFGGLKRGDNFE"
     gene            3071..3247
                     /locus_tag="OE968_002674"
     CDS             3071..3247
                     /locus_tag="OE968_002674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219945.1"
                     /translation="MSKTLSKGTDYKFTKEQIVNSKKYINRKDLLNAILKENELYSFS
                     EVEEIINSFMKGVS"
     gene            3249..4559
                     /locus_tag="OE968_002675"
     CDS             3249..4559
                     /locus_tag="OE968_002675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail sheath family protein"
                     /protein_id="HCP7219946.1"
                     /translation="MALGGGTFVTQNKILPGSYINFISAKRATSSLSDRGIVAIPLEL
                     DWGIDEDVFQVTSDDFEKYSVKYFGYDYTHEKLKGLRDLFKNIRLGYFYKLNKGVKAS
                     CTIATAKYSGIRGNDLKVTVTTNIDDNAKFDVVTLLDNKKVDTQIAKVITDLQDNDYI
                     TWKKDATLEASAGLVFTGGTNGEAVTGAEYQAFLDKIESYSFNALGCLATTTEIKSLF
                     VEFTKRMRDKVGAKFQTVLYKKSDADYEGVVSVENKIKDIGLVESSLIYWAAGVIAGC
                     DINKSNTNKKYDGEFDVDVNYTQIQLEEALKTGKFIFHKVGDEVHVLEDINTFVSFTD
                     DKNDDFSSNQSVRVLDQIANDIATLFNEKYLGKVPNDKAGRISFWNDVVKHHKELENI
                     RAIEDFKTDDVSVELGNDKKTVIVSDAVKVINAMSKLYMTVSVN"
     gene            4576..5046
                     /locus_tag="OE968_002676"
     CDS             4576..5046
                     /locus_tag="OE968_002676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tube protein"
                     /protein_id="HCP7219947.1"
                     /translation="MAQTINAKDTVSAKKAECFITIEGKRYNFMQAIDLEAKMEKNKS
                     EVPILGRTTKGNKTTGSTNTGSATFHYNTSIFRELLYRYKETGEDIYFDIQVTNEDPT
                     SAVGRQTVVLKDCNMDSGIITKFDADGEYLDEDMDFTFEDWELVEKFNLLAGME"
     gene            5118..5558
                     /locus_tag="OE968_002677"
     CDS             5118..5558
                     /locus_tag="OE968_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HCP7219948.1"
                     /translation="MSNLSAFLSQNAIKVDNVKYVASNRFLDKEGKPVEWELKVLSSE
                     EDEALRRKCTKRVKVIGNNGKHTGQYTSEIDYNSYVAELCVASTVFPDLKDAELQNSY
                     GVMGEAQLLKTMLTAGEYVNYTVKVNEVNGFDTSFEDKVEEAKN"
     gene            5899..6060
                     /locus_tag="OE968_002678"
     CDS             5899..6060
                     /locus_tag="OE968_002678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219949.1"
                     /translation="MNNFLLNVIAGVIASLIFCLICKVFLKVKSHSTRGKSKSGWEFD
                     FKIKFHKFK"
     repeat_region   6798..7221
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=6798..6826
                     /rpt_unit_seq="gttttagattaactatatggaatgtaaat"
     gene            7385..7558
                     /locus_tag="OE968_002679"
     CDS             7385..7558
                     /locus_tag="OE968_002679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HCP7219950.1"
                     /translation="MSSKMGRPKVDNPKNIDVKVRFDENTHKKLLDYCEKENLTRTEA
                     IRKGVDLLLEEDK"
     gene            7682..8509
                     /locus_tag="OE968_002680"
     CDS             7682..8509
                     /locus_tag="OE968_002680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin Bro"
                     /protein_id="HCP7219951.1"
                     /translation="MNNELMNFENNELGIKIRTIKYEDGSIGINAEDTAVGFGWCQTQ
                     NKNGKQYVSIRWETINKYCKEFGFLNLLGKDEYIPESLFYLLGMKAKNEIAVKFQTWL
                     AVDVLPSIRQTGAYITNNANPEKLREKASEIEKLQLAYNSTSMLKELLDGAGFDNKSK
                     LLTAKTLYKKAGIDLPIEIEEEESFFDTKQIASKLKIYSKSNKPAQLAVCEIIKKIDL
                     EENEVKGVWETNGSWTGTVNKYTKSVIDKVRNWIEENNRPAKIAGEKKNYHVVYKIE"
     gene            8572..8748
                     /locus_tag="OE968_002681"
     CDS             8572..8748
                     /locus_tag="OE968_002681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219952.1"
                     /translation="MCENLLNEYNLKTDEDVEYFVKFATLLYKLKQDNEEKFQEYAEI
                     LRGILREQQERENK"
     gene            complement(9161..9364)
                     /locus_tag="OE968_002682"
     CDS             complement(9161..9364)
                     /locus_tag="OE968_002682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008982964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCP7219953.1"
                     /translation="MYFNIDKLLESKGRTRYWLAKEVGIAYPNMMKLANNETSSIKLD
                     LFEKLCLVLECTPNELVTLSSKE"
     gene            9608..9994
                     /locus_tag="OE968_002683"
                     /pseudo
     CDS             9608..9994
                     /locus_tag="OE968_002683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013726857.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ORF6N domain-containing protein"
     gene            10058..10411
                     /locus_tag="OE968_002684"
     CDS             10058..10411
                     /locus_tag="OE968_002684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219954.1"
                     /translation="MKLLVTKTFFERAGIELPLEVEEKEHFYDTKQIAKKLGLYTMSN
                     KPAFMAVKQIIRKLDIKEDEMKTVLETNGNWTGTVTKYSNKVTEKVKVWLKENNNPIS
                     IKGDKKNYYILYKNN"
     repeat_region   10843..11794
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=10843..10871
                     /rpt_unit_seq="gttttatattaactatgtggtatgtaaat"
     gene            11924..12439
                     /locus_tag="OE968_002685"
     CDS             11924..12439
                     /locus_tag="OE968_002685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HCP7219955.1"
                     /translation="MFCSNCGYEITGAGKFCSNCGTATLADKVNNDDLFINVHGKELN
                     LTNIYKETKGDKILAIDIAMKLLGLDIKECKNIIYPAFKELSEKINIEEEKEILREDE
                     YKQTNVLEDDVARCPRCGSVSLSAHKKGFGIGKAVAGATIAGGIGLVAGNLGAKKVRV
                     TCLSCGKQFWA"
     gene            12504..14897
                     /locus_tag="OE968_002686"
     CDS             12504..14897
                     /locus_tag="OE968_002686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HCP7219956.1"
                     /translation="MATIQTSIKIFDGMTPAFRNMTNSINTTINSLERLQGRLNNPLN
                     AGNIQASQQSLNNIESILTRIEQKIGRNTNEQENFNNKIRQGSEAGSLLVSKLKSIAG
                     IYIGIKGIDSITKVADTIASTKARLNLMNDGLQTTDQLNKMIYLSAQSARASYADTAA
                     QIAKLGILAGDAFGSSAEVIKFTELMNKAFVIGGTSANEASAAMYQLTQAMGAGKLQG
                     DEFRSIMENAPLLATKIADAMGKTKDQLKELSSSGAITADVIRNALFKASDEIEKKFA
                     SMAITFSQALTMMKNDAYMIFSETLSKISGALQSVRFSEIVVSMRNVMIAISSNIYDT
                     LNIIKNILNSDFFSDFVSNVTLGAILIINGLGWVTNATLNVANVFAQNWSIIAPIIYG
                     VIAAIAIYKGVLLASTIATTVASFVNSLYAVAAYKSCAALAAQEFAIFGKISAQTMEA
                     LVTAQATAAQWGFNAALLSCPIFWIIAGIIAFVVVVFVAVAAVNKFSGTSLTVLGAIV
                     GAVFAAVAFIQNIMIWLFNRCVDVNEGIANGWNQCVYLMKQAIAKGVIFIIEKMASLN
                     DAVNNAGNALGKAFIDGANIAIRGVNKLIDLINKIPGINIGKVGEATFTPVKADNSYI
                     KQQIDSLNKWVGDAPEKIKLDRMGYKDIGAEFQKGNALGTKWQNAITDKFKDTFDINK
                     MLEDAKKKLGLDDLWNKQNPLNNLGGFGGDLGKNVKDTAGNTAKMAKTMDKSQEDLKY
                     LRDIAEQETINRFTGVNIKIDMNNTNNISKDTDVDGIVNVLTEKLNDAMIVSAEGIV"
     gene            14913..15602
                     /locus_tag="OE968_002687"
     CDS             14913..15602
                     /locus_tag="OE968_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HCP7219957.1"
                     /translation="MAYDFYLDGVQLPIPPPKLEIKVTNKNKIVDLINTGEVNILKKE
                     GLSEISFEAEFTHNKLPFYRGAFRDVQFFLSKLELLKTDCKPFQFIVSRELGNKVLFN
                     TNIKVSLEEYAISEDAENGSDTKVAIKLKQYRDYSTKKLVLAPPKNETGRPNVKIEPK
                     RVDSVNATNTKTYTVKAGDSLWSICQKQLGNGSLYKKVYELNKTMMDKANKGKKVPKY
                     TIYKGQVLRLV"
     gene            15595..17487
                     /locus_tag="OE968_002688"
     CDS             15595..17487
                     /locus_tag="OE968_002688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HCP7219958.1"
                     /translation="MSDDLVLANDRDIRLVIAHWEDFYEPAVIDGITWEIERRGSPSK
                     LEFTIAMDDILEFCEGNSVRIYYKGIGIFYGYIFQKKRDKENHIKIVAYDQLRYFKNK
                     DTYVYSNKTASELVKMLAKDFNLKYNVIEDTKYKISRVEENKTLFDMVLTALDDTLRE
                     KKEMYVLYDDFGRITLKNVASMKLDTVMNNDVIEDFDYNSSIDSDTYTKIKLVRDNEE
                     TGKRDVYIAQDSTHMRSWGILQMFDTVDKNMSEAEIKQKCDILLKLYNKKTKSLSLKN
                     VLGDIRVRAGCLVPVFLNLGDIKLQNYMLVEKVKHTFENNSHFMDLTLVDGDEFASYS
                     SSSYSSGNTNNKDEKKNGPAQSITKKNTGKKVPAIFTAYYPGNNAMEGGKTDCNGKPL
                     DVKSRTVAGPMNREGVKKTWYTDDFLKKHPVFEYGDKVKIILPGTAYDNKVYTVKDNG
                     GRIYVETNGTYHIDVLLANASECKKFGRKNGYIIIGGDEEQTYQVEGNNQSSTNNNSK
                     EDKLISIAKSKLGCNYVYGAEGPNNFDCSGFTQWCYKQIGIKIPRTASAQSKAGKAVD
                     LKDRSKWKAGDLLCRIGGGSSNHVVMYIGNNQIIHSPQTGDVVKIESVNSYRKGKAYT
                     HVRRFI"
     gene            17501..17761
                     /locus_tag="OE968_002689"
     CDS             17501..17761
                     /locus_tag="OE968_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2577 domain-containing protein"
                     /protein_id="HCP7219959.1"
                     /translation="MSQDLLQIIKKAAMDAVETSNPMRVVFGTIESISPLRVKIEQKL
                     SIGEIFLIQTDTFKRYTDKKIGDKLVLIRMQGGQQYLILDRM"
     gene            17766..18185
                     /locus_tag="OE968_002690"
     CDS             17766..18185
                     /locus_tag="OE968_002690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2634 domain-containing protein"
                     /protein_id="HCP7219960.1"
                     /translation="MLPSDNLDYDIEDVSIINFDVRQEPSKTFKLHIEKSKIDGICDD
                     VEALKQTIFLILNTERYQHLIYSWNYGVELNDLIGEPISFVIPELERRIKEALIQDDR
                     VENVDNFEFENIKGKVQCKFSVHTKYGNIKAEKVVSV"
     gene            18198..>19042
                     /locus_tag="OE968_002691"
     CDS             18198..>19042
                     /locus_tag="OE968_002691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate J/gp47 family protein"
                     /protein_id="HCP7219961.1"
                     /translation="MTFENIIKRMLDSVPNTLDKREGSIIYNALAPVAVELTETYIAM
                     DELLDQTFVDTASYYYLEKRCKERGITPLPATNTIAKGVFNIDIPLDSRFNLGEYNYI
                     AIERISEKTYKMKCETAGPIFELGKLIPIEYIDGLETAELTEILINGEDEESEDSLRQ
                     RYYDSLNSQSFGGNIQNYKDEVNKIQDVGGVKVYPVWDGGGTVKLVIINSNFKVPSED
                     LVNLVQEEIDPIGHQGQGLGLAPIGHKVTVTGVVSTTINISAEITYKNGYTWENIKSI
                     AEEAI"
BASE COUNT         7569 a         1985 c         3633 g         5855 t
ORIGIN      
        1 cttctacttt gaagaaagtt ttgaggatgt atttatatta aataaaaaag ctgatgcaat
       61 acaatttgtt gttgaagcat agaaaaagga gtgatatata gtgccacaag taaaaaaact
      121 aaatagaata ctaaccatag aagaatgtaa aatagatgat ttcttagaga tgggatatga
      181 tttgatagat gaaactggta aggcagtaaa gtatggcaag tcattaagtg taaaagattt
      241 aatagctgaa aataatattt taaggtcaaa agttgagtct ttagaagaag aaaataagca
      301 gcttaaagag aaaaataaac ttactaaaaa gtaggtgaaa attatggaaa ataatataat
      361 tgatgaaata gaaaaaagac ttgaaagttt tggatatata ttaaaagatg gagataagtg
      421 gttaataggt tttgtaagag aaaaaataga aaatattatt aaactagatt gtaatataaa
      481 aactatgcca attgaattga aagaaattga agttgatatg atagttggag agttcttatt
      541 taccaagaaa aatatgggtc aattagatat agaaagcatt aactttgaag ctgtagaaaa
      601 gtctatatca gaaggtgata caaaggtaga ttttgctata ggaagtggtt ctcaaacacc
      661 agaacaacgc tttgatagct taatagctta tcttactact tatggcaaga ataagatatt
      721 aacctttagg tgcttaagat ggtaagtaaa actagaaaag caatagaaat gttatataga
      781 gataaatgta ctatagttga gtatcagcca attaaagacc ctgtaacaaa acgaactaac
      841 aataaagaag tgattgtatt agaaaatcaa ccatgtaaac tttcatataa aaatatagtt
      901 tctgctacag aagggaaagt agctaagcta gagcaaacta ttaaactctt tatatctcca
      961 gatatagaaa ttaaagcagg ttcaaaactt attataaatg ataaagagta tgtaagaagt
     1021 ggagaatcag ctatatatcc aaatcatcaa gaaataatac ttgagttatt taaggataaa
     1081 gcataatggc tagatggggc agtgttgatt ttagagagtt taaaagagtt tgtaaaaaga
     1141 tggaggagct tacaaagatt gatttagata agttttgcaa ggatgcagca agagaattag
     1201 cagcacgatt acttgggaaa gtaattagaa gaacaccagt tgatacagga ttcttacgac
     1261 aaggatggaa tggagtggct tatgctaggt cgcttcctgt gtataaacaa ggaaataatt
     1321 atattataga ggttgttaat ccgactgaat atgccttaac acaatggggc atataaaacc
     1381 cagcaaaatc ggtaaacgct aagtgtaata gtgttacatt ataaagtagg tagaatatgg
     1441 acatagaata actcttgatt tataatgtat aaaagaggtg attttatggc aaaattttta
     1501 gatattacag gaaaaaaatt tggaaggcta agagtcatta aattttctaa agagataaaa
     1561 agtggtaaaa gaaatagaaa atattggtta tgtaagtgtg attgtggaaa tttcaaagaa
     1621 ataagaactg actctttaac tagtggctta gtacaatctt gtggatgttt aaaaaaagaa
     1681 caagataaat taaatttaac agacaaatac caatttaaaa agaaatataa ggttcaaaat
     1741 aaaagacttt acagtatatg gaagggtata atatctagat gtacagataa aaataataaa
     1801 agatacaata gatatggtga aaggaatata attgtgtgtg atgaatggtt ttgctatgat
     1861 aattttgcaa attgggcatt gagtaatgga tattcagaga aacttacaat tgatagaata
     1921 aataatgaag gaaattatga atcaagcaat tgtagatggg tggatataaa gacacaatgt
     1981 agaaataggt caacaaatat attagtaaag catgaagaaa aagaaattac attgatagag
     2041 ctttctgaaa aaacaggtat ttcatattct tgcttaagaa gtagatattc taagggatta
     2101 gtaggaaata atcttataga aaaagttaag attattgaag aaagcagagc taagttatct
     2161 attgaggatg taaaagaaat tagaaaaaag tattctgatg gatatacaat aaaacaacta
     2221 agtgaaatat atcctgtaac atattcatct atatcaaata tagtccatag aagaacatgg
     2281 aaaaatattt aattaattat atatgccaat accgaggaaa acctatagat tgcgaatagg
     2341 ctataggttt ccgtagagcg tagagagtga ataaatataa tctctccaag agtgctgggc
     2401 aactaaataa agtttatttt gttgatgatg tacgccgaac ttataggaaa ctataagagc
     2461 tagaggataa aaagccttta ggataacaaa atgcatatgt tgaatatggc catagaacta
     2521 aagatggaaa aggttgggtt aaaggacaac atttcttaac aatttcagag atggaactac
     2581 aaagccaagt tgataagatt atagagaaaa aactattaat attgcttaaa ggagtatttg
     2641 atgcttaata atataattga tggaatatct attaaattag ataaaacatt tggagagagt
     2701 tatacaattt atagtgaaga tgtggagcaa ggtataaatg aaccttgttt ttttattgtt
     2761 cctttaaatc caagcaaagt atcctatcca agtggcagga cattaaaaaa gaactctttt
     2821 gatgtacatt attttccaaa aagtaatgat aaatcatttg aaatagatga ggtagctgag
     2881 atgctactgg aggaattaga gtatatagaa attgatggag atttagtcag aggtacaaat
     2941 atgaactttg aaattgtaga taatgtactt catttctttg ttgattataa ctactttact
     3001 ataaaaaata atgatatcaa taagatggat acagtagagt tattcggtgg tttgaagaga
     3061 ggtgataatt ttgagtaaga cattaagtaa aggaaccgat tacaagttta ctaaggagca
     3121 gatagttaat tctaagaagt atataaatag aaaagactta ttaaatgcaa ttttaaaaga
     3181 aaatgagtta tattccttct cagaggtaga ggaaataata aatagcttta tgaaaggagt
     3241 gagttaattt ggcgttaggt ggaggaacat ttgtaacaca gaataaaata ttaccaggta
     3301 gctatataaa ttttatctca gctaagaggg caaccagttc attatcggat agaggtattg
     3361 ttgcaatacc tttagagtta gattggggca tagatgaaga cgtatttcaa gtaaccagtg
     3421 atgattttga gaagtattca gtgaagtatt ttggatatga ttatactcat gagaagctga
     3481 aaggtttgag agatttattc aaaaatataa ggttgggata tttttataaa ttaaataaag
     3541 gcgttaaagc cagttgtact atagccacag caaaatatag tggtatcaga ggaaatgact
     3601 taaaagtaac agttacaaca aatatagatg ataatgctaa gtttgatgtt gtaacacttt
     3661 tagataataa gaaggtagat actcaaatag caaaggttat tacagactta caagacaatg
     3721 actatatcac ttggaagaag gatgcaacac tagaagcaag tgcaggactt gtatttactg
     3781 gtggaactaa tggcgaagct gtgacaggag cagagtacca agctttcttg gataaaatag
     3841 aaagctatag ctttaatgct ttaggatgtt tggctacaac aacagaaatt aaaagtttat
     3901 ttgtagaatt tacaaagaga atgagagata aggtaggagc taagtttcaa acagtactat
     3961 ataagaaaag tgatgcagat tatgaaggtg tagtgtctgt agaaaataag attaaagata
     4021 ttggattagt agaatctagt ttaatttatt gggcggctgg agttatagca ggatgcgata
     4081 taaataaatc taatactaat aaaaagtatg atggtgagtt tgatgttgat gttaattata
     4141 cacaaataca acttgaagaa gctttaaaaa ctggtaaatt tatattccac aaggtgggag
     4201 atgaagttca tgtgttagag gatataaata cttttgtatc atttacagat gataaaaatg
     4261 acgatttttc aagtaaccaa agtgttagag tacttgacca aattgctaat gatattgcaa
     4321 ctttatttaa tgaaaagtat ttaggtaaag ttccgaatga taaggcagga agaataagtt
     4381 tctggaatga tgttgttaaa caccataaag aattagagaa tataagggca atagaagatt
     4441 ttaaaactga tgatgttagt gtagagcttg gaaatgataa gaaaactgtc atagtatctg
     4501 atgctgttaa ggtaataaat gctatgagta agctttatat gactgtttca gttaattaga
     4561 gaggagagtg ataatatggc tcaaacaata aatgctaaag atacagttag tgcaaagaaa
     4621 gctgaatgtt ttataactat agaaggtaaa agatataatt ttatgcaagc tatagattta
     4681 gaggctaaaa tggaaaaaaa taaaagtgaa gttccaattc taggaagaac aacaaaggga
     4741 aataaaacaa ctgggagtac aaatactgga agtgcaacat ttcattataa tacttctatt
     4801 tttagagaat tactttacag atataaagaa actggtgagg atatttattt tgacatacaa
     4861 gttacaaatg aagaccctac atctgctgta ggaagacaga cagtagtact taaagattgt
     4921 aatatggaca gtggaataat tactaaattt gatgctgatg gtgagtattt agatgaagat
     4981 atggatttca cttttgagga ttgggaatta gtagaaaaat ttaatttatt ggcaggaatg
     5041 gagtaaaata cacatttata aattatatat gtgtattttt tatatgaaaa attaaaataa
     5101 aaggagatta gaataatatg agtaatttaa gtgctttttt aagtcaaaat gcaataaagg
     5161 ttgataatgt aaaatatgta gcgagtaaca gatttttaga taaagaaggg aaaccagttg
     5221 aatgggaatt aaaagtttta tcatctgaag aagacgaagc actaagaaga aagtgtacta
     5281 aaagagtaaa agtgattggt aacaatggta agcatactgg acaatataca agtgaaattg
     5341 actacaatag ttatgtagct gaattatgtg tagcatctac agtatttcca gatttaaagg
     5401 atgccgaact ccaaaatagt tatggagtaa tgggagaagc tcagttatta aagacaatgc
     5461 ttacagcagg tgagtatgtc aattatacag taaaagtgaa tgaagtcaat ggatttgata
     5521 catcttttga ggataaagta gaagaagcaa aaaactaatc agaggtggcg attttgatgc
     5581 tagcatcact cattattgta ttcaaaaatt aaagtggaag ccaagtgaat atatgaattt
     5641 agaagttaat gagagagcgt tagcagccgc ctcaatactt ataaagatag aagatgaaga
     5701 ggaagcaatg aaagaagctg aaagagagag aaagagggga cgaagaagat agcaaaataa
     5761 aaaaataaat atagaatagg taaaatatgt aataattata tgttataata tttttagcaa
     5821 gaagatgtaa tctacaattt atagagtgga gttcatactg ggataaaacc tacttcctaa
     5881 tgaaaggagg tgggaagtat gaataacttt ttacttaatg taatagctgg cgttattgct
     5941 agtttaatat tttgcttaat ttgtaaagta tttctaaaag taaaaagcca ctcaactcgt
     6001 ggcaagagta aaagtggctg ggaatttgat tttaaaatca agttccataa gttcaaatag
     6061 attcatttaa ttatgaactt cactctaccg caaaatagat tgtagttctt cttgctttta
     6121 ttataccaca aattagaaaa aatattgttt atataaaata aaaaataaaa atttttatta
     6181 aaaaattgaa aacttgatta taaagcaatt aatttataaa atatatataa ataagtaggt
     6241 atttatttac ttgaatttca ttgtttatat aaaaaaaatg gaaaaatatg taataattat
     6301 atgttataat aattgtagca aggataataa tcgaaagtgc gaagggtgat tattttcata
     6361 ttaaacgcca aattccaaat aaggaaggag gtgaaattat atgataggtt ttttattaag
     6421 catactagct ggtgttatat cagcttatat ttatgacaaa ataaaaaatc acccagacgc
     6481 caataagggt gatttaaaaa aataattctt taaatcaatt ttgatggaaa tagctactct
     6541 tgtataaagt aaattatttc cttgctttta ttataccaca aattggtaca gatattcaaa
     6601 aataatattt ttatgatata ataaaaatgt agagattttg cagtgagcaa tatttgcgat
     6661 aaattgaagt ttaacaattg gaatacaagg tattgagggt gtgtgataaa tgttatcaat
     6721 tgcactactc atggttcact gcaaatttga gagagatgcg tatgtgtagg tattggaaat
     6781 gccaagttta ttttggggtt ttagattaac tatatggaat gtaaattaac ctttttattg
     6841 ttgttgttat tcttattgtt attcgtttta gattaactat atggaatgta aatgttgtaa
     6901 gaagtatcat tctatttttt aatctttctg ttttagatta actatatgga atgtaaatag
     6961 tacatataat gagtctttaa catcagttat gaaaggtttt agattaacta tatggaatgt
     7021 aaatgattgt actttagcgt ctgcactagc tttgtctatc gttttagatt aactatatgg
     7081 aatgtaaatt attttacaga tgaacaatta cagttacttc ttgaatgttt tatattaact
     7141 aagtggtatg taaataatgg aagcaagata atttttaaag gtatggataa ttgttttata
     7201 ttaactatgt ggattcaaaa ttaaatagaa aaaagaaagc acttacttaa atagtaggtg
     7261 cttttgtttt gctcaaaatt ggtcggttga gtaaaataat tagaaaaaat tgggataagt
     7321 tattgacttt ttggaacaca aataatataa ttatattatg gaacacaaaa agtgaggtga
     7381 aacaatgagt tctaaaatgg gaagaccaaa agttgataat cctaaaaata ttgatgtcaa
     7441 agtaagattt gatgaaaata ctcataaaaa attattagat tattgtgaga aagaaaatct
     7501 tactagaaca gaagcaataa gaaaaggagt agacttactt ttggaggaag ataagtaaaa
     7561 aagtagccca acgccgacca aagcatactg gactacttaa cctagagtta tctctatatg
     7621 aaatattcta tcatgtaaag ataactcttt caagataata aatcgaaagg gtgatttttg
     7681 tatgaataat gaactgatga attttgaaaa taatgaatta ggaataaaaa taagaactat
     7741 taaatatgaa gatggaagta taggaattaa tgcagaggat acagctgtag ggtttggatg
     7801 gtgtcagaca cagaataaaa atggtaagca atatgtatca attagatggg aaactattaa
     7861 taaatactgt aaagaatttg gtttcctcaa cttgttgggg aaagatgagt atatacctga
     7921 atcattattt tatcttttag gtatgaaagc taaaaatgaa atagcagtaa aatttcaaac
     7981 atggttagca gtagatgtac taccatcaat aagacaaact ggtgcataca taactaacaa
     8041 tgctaatccc gaaaaactaa gagaaaaagc aagtgagatt gaaaagttac aattagccta
     8101 taacagcaca tctatgttaa aagaattgct agatggtgca ggatttgaca ataaatccaa
     8161 actattaaca gctaaaacat tatataaaaa ggcaggcatt gatttaccta tagaaattga
     8221 agaagaggaa tctttctttg acacaaaaca aatagcatct aaactgaaaa tatattctaa
     8281 gagtaataaa ccagcacagt tggctgtttg tgaaattatt aaaaagattg atttagaaga
     8341 aaacgaagtc aaaggcgttt gggaaactaa tggttcttgg actggtactg taaataaata
     8401 tacaaagagt gtaatagata aggttagaaa ttggatagag gaaaataata gacctgctaa
     8461 gattgcaggt gaaaagaaga attatcatgt ggtttataag attgagtaaa tttatcagtt
     8521 gtattaaata atttagttta gtttatttta gttttgaggg ggattaatac aatgtgtgag
     8581 aatttactta atgaatataa tttaaaaact gatgaagatg tagaatactt tgtaaagttt
     8641 gctacattat tatataaatt aaaacaggac aatgaagaaa aatttcaaga gtatgcagag
     8701 atattgagag gtattcttag ggaacaacaa gagagagaaa ataagtaaaa taatatagat
     8761 aaagcacttg aatattacat agtttcaagt gctttgtttg gtataaaatg gtataataga
     8821 gataagagtt atattaacta tgtggtatgt aaagaatgta taaggcatct tctcaaattc
     8881 tgcgttggtc attttatatt aactatgtgg tatgtaaagt gcgttaactg caataatgct
     8941 gaactcattt cttgatttta tattaactaa gtggtatgta aatgttaatt ccttcaacct
     9001 tctaatagaa gatgctttta ggtttatatt aactaagtgg tatgtaaatg tttcaacatt
     9061 tgacatgtgc tgtggagtaa tgtttatgtt ttatattaac tatgtggatt caaaattaaa
     9121 tagaaaaaag aagcacttac ttaaatagta ggtgcttttg ttattctttg ctagataaag
     9181 taacaagttc attaggtgta cattcaagaa caagacaaag cttttcgaat aaatctaatt
     9241 ttatagaact tgtttcattg ttagctaatt tcatcatgtt aggataagct atacctactt
     9301 ctttagctaa ccaatatcta gttcgacctt tggattcaag taatttatca atgttaaaat
     9361 acattttttc acctcttaag tatattatac aacaattata taatgtttgc aatatataat
     9421 atgcaaacaa tataattata taatgttgac attatataat gtgtgcgata taatatactt
     9481 aaggaataaa aaataagagc cactcgcccc taccaagttt gagtaactct tattgacata
     9541 tactacatat acattaatta tagtatatgt cattccttaa aaaaaatcaa ttaaggagtg
     9601 tgtttttatg aacaatttag tactaattaa caatcaagaa gtgcaagtta aggaatttaa
     9661 taatcaaaga gtagttacat ttaaagaaat tgacagagta catgaaagag tagaaggaac
     9721 agcaggtaga aattttagag aaaataagaa gcactttata aaaaatgagg actattttta
     9781 tttagaagga aaagaattat caacaattaa acagacaacg aatttcgttg gcagtaatgc
     9841 aagagaatta atcttattaa ctgaaacagg ttatctaatg ttagtaaaat cttttacaga
     9901 tgatttagct tggaaagtac aaagacaatt ggtaaatagt tattttagag ttaaagaaga
     9961 aaagaaagaa atgaaagcat tagaaaaatt agaaacagtt aatgagtcaa ttaggttaat
    10021 aactccaatt tttgatgatt taaacattga taaaagtatg aaacttcttg taactaagac
    10081 tttttttgaa agagcaggta ttgaattgcc tcttgaagtt gaagaaaaag aacattttta
    10141 tgatacaaag cagattgcaa aaaaattagg actttacaca atgtctaata aaccagcatt
    10201 tatggcagtt aagcaaatta taagaaagct tgatattaaa gaagatgaaa tgaaaacagt
    10261 attagaaacg aatggcaatt ggactggtac tgtaacaaaa tattctaata aggttacaga
    10321 aaaggtcaaa gtgtggttga aagaaaataa taatcctatc tcaatcaaag gagacaagaa
    10381 aaactactat atattgtata aaaataatta gattttagtt tttggggggg taatacaatg
    10441 tatgagaatt tacttgatag tatagatatt gaaaagagaa aagaagaatt tagaattaaa
    10501 cttttgaaaa taagagaaac agatatagat atatatatat aataagatag aaagaatagt
    10561 atataaactt tctgagaaaa aattagagaa aaataattaa ataaatagat aaagcacttg
    10621 gatattatgt tgtttcaagt gctttatttg gtataaaatg gtataataaa aatataggaa
    10681 ttttgcagtg ttcgattttt ctacttaagt atagtttaac aattggaata caaggcattg
    10741 agaaggtttg ataagtgtta tcaattgcac tattacccgc tcactgcaaa tttgagaaag
    10801 ttatatgtgt gtaagtcttg gaaatacaca atttattttg gggttttata ttaactatgt
    10861 ggtatgtaaa tctttttaaa aaagcacgtc aattacaata ctaaaattgt tttatattaa
    10921 ctatgtggta tgtaaatttg aaaactgcat gttctttaac aaaagcatct aattgtttta
    10981 tattaactat gtggtatgta aatgtattac tcccaattat gaacatagga tatagtcttt
    11041 gttttatatt aactatgtgg tatgtaaatt atagtttgcc atatgttcct ggttcgtatg
    11101 attggggttt tatattaact atgtggtatg taaataaatt taatattact ggaaaaggag
    11161 aaatggatat cggttttata ttaactatgt ggtatgtaaa ttttgttata agaatatcgc
    11221 caccttcctt ttctggtgtt ttatattaac tatgtggtat gtaaattttt ctgcatcttc
    11281 tactatgtta tattcttcta atggttttat attaactatg tggtatgtaa atgcacattt
    11341 aacttcaagt cttagagtat tatctgcaag ttttatatta actatgtggt atgtaaattt
    11401 cgttcaactt ttatcttagc ttctcctgct acttgtttta tattaactat gtggtatgta
    11461 aatgtactag aaaatgcact acctgcattc attcctatac ggttttatat taactatgtg
    11521 gtatgtaaat gtgctatttc caactttttt ttcaagttct gaatactgtt ttatattaac
    11581 tatgtggtat gtaaattagt tagtcccata tcgttatggt actgcattaa cgcgttttat
    11641 attaactaag tggtatgtaa atagtgtaaa aggcattttt tcaaattgtg cattggtttg
    11701 gtttatatta actaagtggt atgtaaaggc taatgtttga gtatttaaaa gcatctgagc
    11761 aaacaatttt atattaacta tgtggactta aaattaaaaa taattcaaaa acacttacaa
    11821 atgagtaagt gtttttttaa tgaaaggagg tgataataat gtaaaaattt tacgtatata
    11881 gtataatagt gctataaaat aagtattatg tgaggtgatt gttgtgtttt gttcaaattg
    11941 tggttatgag ataactggtg caggcaaatt ttgctcaaat tgcggaacag ctacattagc
    12001 agataaagtt aacaatgatg atttatttat aaatgttcat ggaaaagaat taaatctgac
    12061 taatatttat aaagaaacta aaggagataa aatcttagca attgatattg caatgaagtt
    12121 actagggctg gacataaaag agtgtaaaaa tattatatat ccagctttta aagaattaag
    12181 tgaaaaaata aatatcgaag aggaaaaaga gatattgagg gaagatgagt ataaacaaac
    12241 taatgtactt gaagatgatg ttgctcgttg ccctaggtgt ggctctgttt cattgtctgc
    12301 tcataagaaa ggttttggca taggaaaagc tgtagcaggg gctactatag caggaggcat
    12361 tggtttagta gctggaaatt taggagcaaa gaaagttaga gttacatgtt tgagctgtgg
    12421 taaacagttt tgggcataaa taataaacac ttactaatgt aggtgttttt ttatatggaa
    12481 atttatgaaa ggagagtgag gaaatggcta caatacaaac ttcaataaag attttcgacg
    12541 gaatgacacc agcatttcgt aatatgacta attctattaa tacaacaatt aatagtttag
    12601 agagattgca aggcagattg aataatccac tcaatgcagg taatatacaa gcttctcaac
    12661 aaagtttgaa taacatagaa agtattctca caaggataga acagaaaatt ggaagaaata
    12721 caaatgaaca ggaaaacttt aataataaaa taagacaagg tagtgaagca ggttctctat
    12781 tagtgtctaa attaaaaagt attgctggga tatacattgg aataaaagga atagatagta
    12841 ttacaaaagt agcagataca attgcaagta caaaagcacg tttaaatcta atgaatgatg
    12901 gcttacagac aacagaccag cttaataaaa tgatttattt gtcagcccaa agtgcaagag
    12961 ctagttatgc agatacagca gcacagattg ctaaacttgg aatacttgca ggagatgctt
    13021 ttggaagttc agcagaggtg ataaagttta cagaacttat gaataaagct tttgtaattg
    13081 gaggaacatc agcaaatgaa gctagtgcag caatgtatca attaacacaa gccatgggtg
    13141 caggaaaact tcaaggtgat gagttccgtt ccataatgga aaatgcacct ttattagcca
    13201 ctaaaatagc tgatgcaatg ggaaaaacta aagaccaatt gaaggaatta tcaagtagcg
    13261 gagcaataac agcagatgtt ataagaaatg cactgtttaa agcttctgat gagatagaaa
    13321 agaaatttgc aagtatggca atcacttttt ctcaagctct cacaatgatg aaaaatgatg
    13381 cttatatgat attttctgag actctcagta agataagtgg agctttgcaa agtgtacgtt
    13441 ttagtgagat tgttgtatct atgcggaatg ttatgattgc aatatcttca aacatttatg
    13501 atacattaaa tattataaaa aatatattaa atagtgattt tttttcagat tttgttagca
    13561 atgttacatt aggagctata ctaattatca atggactggg atgggttact aatgcaacac
    13621 taaatgttgc taatgtcttt gctcaaaatt ggtcgattat tgctcctatt atttatggag
    13681 tgatagcagc aattgcgata tataaaggag tattacttgc aagtacaatt gccactacgg
    13741 tagcatcttt tgtaaattca ttgtatgcag tagcagcgta taaatcttgt gcagctttag
    13801 cagcacaaga atttgcgata tttggaaaaa tatctgcaca aacgatggaa gctttggtaa
    13861 cagcacaagc aacagcagca caatggggtt ttaatgcagc attattatcc tgtccaattt
    13921 tttggataat agcaggtatt atagcatttg tagtagtagt ttttgttgca gtagcagcag
    13981 taaacaaatt ctcaggaaca agtctgactg tactaggagc aattgtaggt gcagtatttg
    14041 cagcagtagc atttatacaa aacataatga tatggctatt taatagatgc gtagatgtaa
    14101 atgaagggat tgcaaatgga tggaatcaat gtgtatatct aatgaaacaa gctattgcaa
    14161 aaggtgtaat ctttataatt gagaaaatgg catcattaaa tgatgctgta aataatgctg
    14221 gaaatgcact tgggaaagct ttcatagatg gggcaaatat cgcaatacga ggtgtaaaca
    14281 aattaattga cctaataaat aaaataccag ggataaatat tggtaaagtt ggagaagcaa
    14341 catttacgcc tgtcaaggca gataatagtt acatcaaaca acagattgac agtttaaata
    14401 aatgggtagg agatgcacca gaaaaaataa aattggatag aatgggatat aaagatattg
    14461 gagcagaatt tcaaaaagga aatgcacttg gaactaaatg gcaaaatgct ataactgata
    14521 aatttaaaga tacttttgac attaataaga tgctagaaga tgcaaagaaa aaattaggat
    14581 tagacgattt gtggaataaa caaaatcctt taaacaacct tggtggattt ggtggagatt
    14641 taggaaaaaa tgtaaaagac acagcaggaa acacagccaa aatggctaaa acaatggata
    14701 aaagtcaaga agaccttaaa tacttaagag acattgcaga acaagaaaca ataaacagat
    14761 tcacaggagt aaacataaaa attgatatga acaatactaa caatataagt aaagacacgg
    14821 atgtggatgg tatagtaaat gttttaacag aaaaactgaa tgatgctatg attgtatcag
    14881 cagaaggaat agtttagaaa ggagggatat aaatggctta tgacttttat ttagatggag
    14941 tacaattacc aatacctccg ccaaagttag agattaaagt tacaaataaa aacaagatag
    15001 ttgatttgat aaatactgga gaagtaaaca tactaaaaaa agaaggatta tctgaaataa
    15061 gttttgaagc agaatttaca cataataagt tgccattcta tcgtggagct tttagggatg
    15121 ttcaattctt tttaagtaaa ctggaactat taaaaactga ttgtaagcca tttcaattta
    15181 ttgtatcgag ggaattaggt aataaagtac tatttaacac taatataaaa gtatctcttg
    15241 aagagtatgc tatttcagaa gatgcagaaa atggttcaga tacaaaagtt gcaataaagt
    15301 taaagcaata tagagattac tcaactaaaa agttagttct tgcccctcct aaaaatgaga
    15361 ctggtagacc taatgtaaag atagagccaa aacgagttga ttcagtcaat gccacaaaca
    15421 ctaaaacata tacagtaaaa gcaggggata gcctttggtc aatttgtcag aagcaacttg
    15481 gtaatggttc gttatacaag aaagtatatg agttaaataa aacaatgatg gataaagcta
    15541 acaagggtaa aaaagtacct aaatatacca tctataaagg gcaggtgttg aggcttgtct
    15601 gatgatttag ttctggcgaa tgatagagat ataaggctag ttattgcaca ttgggaagat
    15661 ttctacgaac ctgctgtcat tgatggtatc acatgggaga tagaaagaag aggttcacct
    15721 tcaaagttag agtttactat agcaatggat gatatattag agttttgcga aggtaattct
    15781 gtaaggatat attataaggg aattggcata ttttatggat atatatttca gaagaaaaga
    15841 gataaagaaa atcacattaa aatagttgct tatgaccagt tgagatattt taaaaataaa
    15901 gatacttatg tatatagtaa taaaacagca agtgaacttg taaagatgtt ggctaaagat
    15961 tttaatttaa aatacaatgt catagaagat acaaaatata aaatatcgag agttgaagaa
    16021 aataaaacac tctttgatat ggtcttaact gcactagatg atactctaag agagaaaaaa
    16081 gaaatgtatg tgttatatga tgattttgga agaataacat taaagaatgt tgcatcaatg
    16141 aaattagata ctgttatgaa caatgatgta atagaagact ttgactataa ttcatcaata
    16201 gatagtgata cttacacaaa gattaaactt gtgagagata atgaagaaac aggaaaaaga
    16261 gatgtgtata ttgctcaaga ctcaacgcat atgaggagtt ggggaatact tcaaatgttt
    16321 gatacagtag acaaaaacat gagtgaagca gagataaaac aaaagtgtga tatacttcta
    16381 aaactatata ataagaaaac taagtcatta agtttaaaaa atgtacttgg agatattaga
    16441 gtgagagcag gttgtttagt acctgttttt ttaaatctag gagatattaa acttcaaaat
    16501 tatatgctag ttgagaaagt aaaacatact tttgaaaata acagtcattt tatggatttg
    16561 actcttgttg atggagatga atttgcttct tattcttcaa gctcatattc aagtggaaat
    16621 actaacaata aggatgaaaa gaaaaatggt cctgcacaaa gtattacgaa aaaaaataca
    16681 ggtaaaaaag ttcctgctat atttactgca tattatccag ggaacaatgc aatggaaggc
    16741 ggaaaaacag attgcaatgg aaagccactt gatgtaaaat caagaactgt tgctggtcca
    16801 atgaatcgag aaggagttaa gaaaacttgg tatactgatg attttctaaa gaaacatcca
    16861 gtttttgaat atggagataa agtaaaaatt atacttcctg gtactgccta tgacaacaaa
    16921 gtatatacag ttaaagataa tggaggaaga atatatgttg aaacaaacgg aacatatcat
    16981 atagatgtac tattagctaa tgctagtgaa tgtaaaaaat ttggtagaaa gaatggctat
    17041 ataattatag gtggagatga agaacaaaca tatcaagttg aaggtaataa ccaaagtagt
    17101 acaaataata actctaaaga agataaatta attagtatag caaaaagtaa actgggttgt
    17161 aattatgtgt atggagcaga aggtcctaat aattttgatt gcagtgggtt tactcaatgg
    17221 tgttataaac aaataggtat aaaaattcct cgtactgctt ctgcacaaag taaagcagga
    17281 aaagcagtag atttaaaaga tagaagcaag tggaaagcag gagacttatt atgtagaatt
    17341 ggaggaggaa gtagtaatca tgttgtaatg tatattggaa acaatcaaat aattcattca
    17401 ccacaaacag gagatgtggt aaaaatagag tctgttaatt cttatagaaa aggaaaagca
    17461 tacacacatg tgagaagatt tatataagtg aggtggcaat atgagccaag atttattaca
    17521 gataataaaa aaagctgcaa tggatgcagt agaaacaagc aacccaatga gggttgtatt
    17581 tggaacaata gaaagtatta gtcctctaag agttaagata gaacaaaaac tatctattgg
    17641 tgaaattttt ctaatacaaa cagatacatt taaaagatat acagataaaa aaataggaga
    17701 taaattagtc ttaattcgta tgcaaggagg gcaacaatac ttgattttag ataggatgtg
    17761 ataaagtgtt accaagtgat aatttagatt atgatattga agatgtatca ataattaatt
    17821 ttgatgtaag acaagagcca agtaagacat ttaaacttca tatagaaaag tctaagattg
    17881 atggtatttg tgatgatgta gaagcattaa aacagaccat ctttttgatt ttaaacacag
    17941 agagatacca acatctaata tatagttgga attatggagt cgagttgaac gaccttattg
    18001 gagagcctat atcctttgta ataccagagt tagagagaag aatcaaagaa gcactaattc
    18061 aagatgatag ggttgaaaat gtagataatt ttgagtttga aaatataaag ggtaaagtac
    18121 aatgtaaatt ttcagttcat acaaaatatg gaaatataaa agcagagaag gtggtgagtg
    18181 tataattgtt tgagttaatg acatttgaaa atataattaa aagaatgtta gatagtgtac
    18241 ctaacacact tgataagaga gaaggttcta taatatacaa tgccttggca ccagttgcag
    18301 tggagcttac agaaacatat attgctatgg atgaattact agaccaaaca ttcgtagata
    18361 ctgctagtta ttactattta gagaagagat gtaaagagcg aggaattaca cctttaccag
    18421 ccactaatac aattgctaaa ggagttttta acatagatat tccacttgat tctaggttta
    18481 atctaggaga atacaattat attgcaattg agagaatatc tgaaaaaaca tataaaatga
    18541 aatgtgaaac tgctggacct atatttgagt taggaaaact aatacctatt gaatatatag
    18601 atggtcttga aactgctgaa ctaactgaaa tcttgataaa tggagaggat gaagagtcag
    18661 aagatagttt aagacaaaga tattatgata gcctaaattc acagagcttt ggtgggaata
    18721 tacaaaacta taaagatgaa gttaacaaaa tacaagatgt tggaggagtt aaggtttatc
    18781 ctgtgtggga cggtggagga actgttaagt tagtaataat taactctaat ttcaaagtac
    18841 catcagagga tttagttaat ttagtgcaag aagaaattga cccaattgga catcaaggac
    18901 aaggcttagg attagcacca atagggcata aagttactgt tacaggtgtt gtaagtacaa
    18961 ctataaatat atcagcagag ataacataca aaaatggcta cacttgggag aatataaaat
    19021 caattgcaga agaagcaata ga
//
LOCUS       DAJMZY010000081        18834 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.081, whole genome shotgun sequence.
ACCESSION   DAJMZY010000081 DAJMZY010000000
VERSION     DAJMZY010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18834)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18834)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18834
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.081"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            76..993
                     /locus_tag="OE968_002692"
     CDS             76..993
                     /locus_tag="OE968_002692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WYL domain-containing protein"
                     /protein_id="HCP7219962.1"
                     /translation="MMILIQSRGKMKCKELSEELEVSERQIKSYKMYLEQAGIFINST
                     PGIYGGYEIDKCNSISLIKLLDSEVSILDMINSQLEYNNDIYKNEFNNIVEKIKAVLN
                     TGEKSDTYMDYFTVQAQRNCDYESEKNKCNEIIRAYTTKHKFWIEYYSLNSGNSERIV
                     HPYGLFNYKSDTYMVAFCEKRFKFIDFKLCRIKDYKVLEEKYNVDKSFSWDEYSKNSI
                     GIYKGEEINVVIKISHPFSTIIKEKVWVNNQQIIEYDDKSIMFKAKMRGYEEIKSWIL
                     SMGAYVEVVEPDRLRNDILLEIEKMKKIY"
     gene            1071..1808
                     /gene="cas6"
                     /locus_tag="OE968_002693"
     CDS             1071..1808
                     /gene="cas6"
                     /locus_tag="OE968_002693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endoribonuclease Cas6"
                     /protein_id="HCP7219963.1"
                     /translation="MKMKIEFSTGCIPISYNSLFMSIIKEAIRKSNEDYYKNMYYYKE
                     KNNKKTKNFTFSVYIKKYSIEGDNFIIEDKVILNISTPDLELGFHIYNGLMTSKKCLY
                     KDYELTRIRIDLSREKKVTEERVLFNALSPICVKSKEGKFLEITDDRYIEELNYITNE
                     VVKNYRGNGLKRKLEFENIGLKKVVVKESLREFKKITGKEYQYINGYKGKFILKGDID
                     DLNLIYNLGIGFRRAQGFGDVDILEWR"
     gene            1814..3664
                     /gene="cas8a1"
                     /locus_tag="OE968_002694"
     CDS             1814..3664
                     /gene="cas8a1"
                     /locus_tag="OE968_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated protein Cas8b1/Cst1"
                     /protein_id="HCP7219964.1"
                     /translation="MKLRVYRGDWFFNMGIVGFLNIIKKADKQAEIFIMEDYIEFDSL
                     FLENFHEYYFNYFMDEYDVSKRIKKNIDYSINFIKSKPDRIKDGIKKIKDSVKQQNDK
                     IKKFDEEKFNMIKEKLDSMSKIKSYDEFDSLEALVDETIDIFKIKSINDRLTANLYKY
                     VVQDNYFGQVSFFNVAKAKLDLDGLKQVMFNDYLRQIIYFGELEDLLEENDYDKLKNY
                     LNDRLNSIAKDINEKKVSKSSINTIEKIMKEINKNFIKKNKSIEDIKKYMDSLEVCEM
                     CGLYKGILDEYSESNFAPLGVSTNNARNMFWNQAYVPSICDICKLILFCTPAGATYTR
                     KNYLINEENEFYLFVNMDTCINELFERNNSLKAQKSEYSDSKDENPFNQLIKSIVEEN
                     TLKSEWQLRNILFVEFKASIDSKKCKINYFNIPTYLAKFFVKENKKIQSIYDYKLKSN
                     VLDLILKSKDLKHLINNTLRNIVKSNLESNNKSNISGLSCFNVVQLRTILNNYKRGVY
                     KMDYKKLRKIYESGCEIHDYYIDKNAKNKIEGITYKILNLIKVGNKNDFMQTILRIFS
                     PSEKTPPEEILQIFVEEDLDFESVGYAFVTGLISGKYEGKDKLPNEKEEK"
     gene            3666..4580
                     /gene="cas7i"
                     /locus_tag="OE968_002695"
     CDS             3666..4580
                     /gene="cas7i"
                     /locus_tag="OE968_002695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated protein
                     Cas7/Cst2/DevR"
                     /protein_id="HCP7219965.1"
                     /translation="MKRGLTFTVIAQAQSLNYGEGIGNISELKKLSRDDGNIYTFASR
                     QCLRYDIVRLAAELFNWNLQVVDKEKGTIQFKDNISIRESEEMDLFGYMKTNKKDEKD
                     KKGGSLTREATVRLSNAISLEPYRSDMDFLNNKGLADRIGEHPNLANIEQHLSYYTYT
                     VTIDLSKIGKDGDIELDNKEKCRRVVEFLEIIKVLNRNIRGRQENLSPLFVVGGVYEI
                     ANPFFLGRIKLKGDKNGFKINKQAIEEVIQGTFLGKDLKEFTYVGMVDGVFINKEEFK
                     GLFEDNFLSVDKFFGQLVKEVKEYYGVN"
     gene            4582..5283
                     /gene="cas5b"
                     /locus_tag="OE968_002696"
     CDS             4582..5283
                     /gene="cas5b"
                     /locus_tag="OE968_002696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated protein Cas5"
                     /protein_id="HCP7219966.1"
                     /translation="MKVLKLDLFQETACYKKPFAMKITETYPLPPYSTINGLIHKILN
                     ATEYIPFNISVQGTYESIFNNYQTTYFYKKDSITSMPMNSHMLLNVNLIIHIGGDFDL
                     LEEIYDSLLNYDEHLSLGRKEDLVRINDIRFVEVNKFEVDEDIQLDDYENYKLSECNI
                     RMPIYIPKTSLQDTDIDGISYRLNNYYDNNAVEDKKRVWNKVDSYYVEDGNTISIGDI
                     LLDNEGDLLYFNNIN"
     gene            5294..7615
                     /locus_tag="OE968_002697"
     CDS             5294..7615
                     /locus_tag="OE968_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated helicase/endonuclease Cas3"
                     /protein_id="HCP7219967.1"
                     /translation="MLYAKSNPVETLREHTDELLKQMNVLRESYGKNINSLDFLEEEI
                     FWQLLDFVIEFHDIGKAFSPFQELIKSRMDTKINEPKIVTYLENNVGHNYLSPAFIDY
                     SYIDRKKNKELRAVLNQVIVYHHERDIFIDKDFKNLIQKILDEDLINKVYELQHEFKV
                     RYPIKTEKLSKVYLQSVEKRIDKNHKYYNLYIMLKGILHRLDHSASAHEVVECNNVIN
                     IGEQTENYLMKEFGSLREAQSFAKSNRNKNIILIASTGMGKTETALIWIDKDKAFFTL
                     PLRVSINALFDRAKNIVGVGESNDTFLGLLHSTAIDYLEESNQENSSEIVDLAKLLSC
                     KLTFSTIDQIFKFPFLYRGYEKVYSTLAYSKVVIDEIQAYSPEIAAVLVKGIEMIHKI
                     GGRFMIMTATMPTIYIDELKKRGVMNSNLAELTCNTEKIRHCVSIVENSIDENLGKII
                     QSGMNKKVLVIVNTVKSAVEKYELIEEIVKPKGIDVNLNLLHSMYIQEDRAKLEKYIK
                     EFANSDRNGIWITTQLVEASLDIDFDELHTENSTLDSLFQRFGRCYRSREYEENSPNI
                     FIYTEKATGIGSIYDKDIVEKGLELLKTFINGKECVKMKEKYKVEMVKILYSKESLEG
                     TAFEKRFTSALNILDTITPYSLGSKDAQNILRNIEGYTVIPEDIYNKIEETLIKDYEE
                     LGQELINAYSNDDRQLINKIKSKRKKARREIIKKTVNLPIYKAKQNVIDIQVKGLEDL
                     KILLYKYDIYENKHTKQIFGKGVLISNEIDQFI"
     gene            7630..8181
                     /gene="cas4"
                     /locus_tag="OE968_002698"
     CDS             7630..8181
                     /gene="cas4"
                     /locus_tag="OE968_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated protein Cas4"
                     /protein_id="HCP7219968.1"
                     /translation="MWLKFTKEGDFVPIDLEVLKVQGVKINYYYVCKRKLWLFSKGIT
                     MEQNSSRVLSGKIVHEDSYKRMKNKEILIDDILKLDIIKDEYVKEVKISSKMKEADEM
                     QLYYYLYYLKNSMGIEKKGTINYVKEKKQEELILTEEKERIIENTLININEINMQLSP
                     PKIEKKHYCTKCAYYEFCFVKEE"
     gene            8184..9164
                     /gene="cas1b"
                     /locus_tag="OE968_002699"
     CDS             8184..9164
                     /gene="cas1b"
                     /locus_tag="OE968_002699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated endonuclease Cas1"
                     /protein_id="HCP7219969.1"
                     /translation="MYKDYYIISNGDIKRKENTIYYYNLEGEKKILPVEQVDDIHIYG
                     EVDLNTKLINYISKYGVMLHFYNYYGYYSGTYYPRKKNVSGFSLVCQSACYLDKNERL
                     YLAKSFVESASYHILRNMRYYKVDESLIDTIKDELNDLNDVKEISELMGKEGRIRKTY
                     YKSFNQILKDDFEFYKREKRPPKDPVNALMSFGNSIMYTNVLSEIYKTQLDPTISFLH
                     EPSTKRFSLSLDIAEIFKPIIIDTIIFSLINNKRINKNDFEYQDKICYLSEKGKKKFL
                     QEFENKMQTTIKHRNLNRKVSYRMFIRLECYKLIKHFINDERYKVLKVWW"
     gene            9167..9433
                     /gene="cas2"
                     /locus_tag="OE968_002700"
     CDS             9167..9433
                     /gene="cas2"
                     /locus_tag="OE968_002700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endonuclease Cas2"
                     /protein_id="HCP7219970.1"
                     /translation="MFVIVTYDIVEARSLNRIRRILRKYLTWTQNSVFEGNITEGKLH
                     KCISEIENIIDNSEDSIYVYEIKNPNSIKKKCYGIDKYSDEMFI"
     repeat_region   9617..11345
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=9617..9645
                     /rpt_unit_seq="gttttatattaactaagtggtatgtaaat"
     gene            11406..11834
                     /locus_tag="OE968_002701"
     CDS             11406..11834
                     /locus_tag="OE968_002701"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HCP7219971.1"
                     /translation="MIKKLNNKDINKIMEIWEKSTIKAHDFISKEYWQNNYNTVKNEY
                     IPISDTFVYDDGDEIKGFISIIDKSFIGALFIKPKYQNLGIGGKLLDYATKKYKSLSL
                     AVYKDNKKAVVFYNKKGFNIVKEQVNEDSGFKEYIMEYSK"
     gene            complement(12289..13068)
                     /locus_tag="OE968_002702"
     CDS             complement(12289..13068)
                     /locus_tag="OE968_002702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219972.1"
                     /translation="MKVNENNINNIDEELDELSRKVYLESPDFWISISDKIIDKVFDE
                     MLLFFAVKYNYFNIVCFAIENNYLDLNMPSKNKKYTNIMEHLLDTSKQNEDKKIYNYL
                     LSLNKGNNLDERPILDELNCNISSDTFEKKDIYLPKYLCPSCNSNIFDTGYKVSNDIT
                     YKFSSKEAEPIEMCSEVSSIRCCNCDELLEDITLDKLYNLCKIQNCNNCGSNLTKVGI
                     IAKKKMNFDENTEKFKDVSTSYCCGNCDSEINLSQREHFKI"
     gene            13392..13937
                     /locus_tag="OE968_002703"
     CDS             13392..13937
                     /locus_tag="OE968_002703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HCP7219973.1"
                     /translation="MKNTKVNIQDLTKMSICVALLCISSYIYIPLPFTPAGVTAQTIM
                     INLIALILTPRQAFSTVGVYIMIGLIGIPVFGGGTSGIGKLLSPTGGFYFGFLFAALI
                     ISLLKGRNNDIKRYILITIFVGMPIIYFMGTVFMCYFNQMTVEAALFAAVVPFLIGDT
                     IKSVIASFLGTKLNNVLRRNL"
     gene            13969..15105
                     /locus_tag="OE968_002704"
     CDS             13969..15105
                     /locus_tag="OE968_002704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiolase family protein"
                     /protein_id="HCP7219974.1"
                     /translation="MKEVFILGGLRSHIGLKNGIFQFVQPELLGASVLKDLIKKYEID
                     KIDEIICGNAVGTGGNIARLMTLTAGVSNEVPAFTVDMQCASAMMSIDIAFSKVKSGQ
                     CDLIIAGGFESSSLQPMRTYHKNDKRYNTNNPNYTVAQFSPDDNSQNSMLEGAERVAE
                     LYQIEKADLDFWVKESHKRAKEAREEKILEDIISPINNSTYDEGIRDKMSQRLLDRMP
                     SILGKETITNAANSCLINDGASFIIICSKKYLEHVKKKPKAKIINTCTIGTDATLSPT
                     SAIQAMDKLLEIESLNYLDVSAVEFNEAFAVIDVLFQRKYPELIDRYNIFGGALAYGH
                     PYGASGAIIALHLLKALEKTKGRYGICSIAAAGGLGSALLLERV"
     gene            15109..16500
                     /locus_tag="OE968_002705"
     CDS             15109..16500
                     /locus_tag="OE968_002705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HCP7219975.1"
                     /translation="MNYYELLRIKKERHKNKNFLIIDGEKYTYENILSYSEELGKQIS
                     LGENIPILIYSKNIMFQLISFFAINYSKNIPIICHYNLSKKVLDDILLKNNISIIISD
                     ESMDVIDLYDDNNNEVAKKVNFSIFNPKFNIYMYQYKNLINYLDKSICMGALSSGSTS
                     VPKVLYRTYESWAGFFPIQNGIFNISGESILFVNGTLSFTGNLNSIMSVLYEGGSIVI
                     SSGLNCKSWIRIIKQYNVTNIYLIPTKLQLLVKHLKEPVLKVVSIFTGSQLLFEDTAR
                     NLKKYMPKSEIILYYGASELNYITYLCYDELIEKPLSVGRPFPGIDIYIREGKIFVNT
                     EYAVYNATKPYSVNDIGYYDNDGYLIFEGRSDDILNIGGFKVSSTKIENEVKKIPQIE
                     DAIVLPYSDTIRGNQIVLFVITIDKITKKDLLIKMKDNLMKNEIPKKIIFLNSFPYTS
                     SEKIDRLALLKML"
     gene            16576..17451
                     /gene="dpsA"
                     /locus_tag="OE968_002706"
     CDS             16576..17451
                     /gene="dpsA"
                     /locus_tag="OE968_002706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipicolinate synthase subunit DpsA"
                     /protein_id="HCP7219976.1"
                     /translation="MSNQYDITVIGGDLRQVYMVKKLINKGYSVVTYGISNEIINGIV
                     GKSTSLAEALSKSSIILCPIPFTKNQVNIENTDDCLDATIDNLLINLSPNQILFGGNI
                     PTKVCKFCEQHSIQIYDFMKMNDVAILNAVATAEGAIAEAIKRSIINIHQSNCLVLGY
                     GRCAQILAKKLYALDANVCVGARNNDARSTANAFGYSSISLSQLDEKLLQFDYIFNTI
                     PECILTKERLEKVSQEVTIIDIASSPGGVDYSVVKEAGINATLCLGLPGKYSPKTSGE
                     ILVNAIENIINERRD"
     gene            17454..18044
                     /locus_tag="OE968_002707"
     CDS             17454..18044
                     /locus_tag="OE968_002707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipicolinate synthase subunit B"
                     /protein_id="HCP7219977.1"
                     /translation="MRLEGLTIGVGFTGSFCTYDKIFIELENLVKEGANVHTIFSDVS
                     QNIDCRFGNSEEFMKKAYELTGNKPIVTIEEAEPFGPKGIADIIIIAPCTGNTAAKLA
                     NGITDSPVLMAAKGHLRNDKPLVISISTNDALSFNFKNIGILLNSKNIYFVPFGQDNC
                     KAKPNSMIAHTELIIPTIELALENKQLQPVIKSPHQ"
     gene            complement(18251..18451)
                     /locus_tag="OE968_002708"
     CDS             complement(18251..18451)
                     /locus_tag="OE968_002708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219978.1"
                     /translation="MEKLKTISVFSLIISVILTIGGIGIVTYYVDNLFIRGLSVFVLI
                     MSSSFVSTTVRLIFEESKRYKF"
BASE COUNT         7656 a         1787 c         3012 g         6379 t
ORIGIN      
        1 gaaataaata ataaaaatat caattaatgt tattaggggg ggttactcat tagtaaatta
       61 gctaatacac ttagaatgat gatattaatt caaagcagag gcaaaatgaa atgcaaagaa
      121 ttatcagaag agttggaagt aagtgaaagg caaataaaaa gttacaagat gtatttagag
      181 caagctggta tatttataaa ttcaacacct gggatttatg gtggttatga aatagataaa
      241 tgtaatagca tctcattaat taaattatta gatagtgaag tttcaattct agatatgata
      301 aattcacagt tagagtataa taatgatatt tacaaaaatg aatttaataa tattgtagaa
      361 aaaataaaag cagtattaaa tacaggagaa aaaagcgata catatatgga ttattttaca
      421 gttcaagcac aacgtaattg tgattatgag tctgaaaaaa ataagtgtaa tgaaataatt
      481 agagcatata ccacaaaaca caaattttgg atagaatatt attcattaaa ttcaggaaat
      541 agtgaaagaa ttgttcatcc atatggttta tttaattata aatcagatac ttatatggta
      601 gctttttgtg aaaaaagatt taagtttata gactttaaat tatgtaggat taaagattat
      661 aaggttttag aagaaaaata taatgtagat aaaagtttta gttgggatga atatagtaaa
      721 aatagtatag gaatttataa gggagaagaa attaatgttg ttataaaaat tagtcatcca
      781 ttttcaacaa ttataaagga gaaagtttgg gttaataatc aacaaatcat agaatatgat
      841 gataaatcta taatgtttaa agctaaaatg agaggttatg aggagataaa aagttggatt
      901 ttaagtatgg gagcttatgt tgaggttgta gaaccagata gacttagaaa tgatatattg
      961 ttagagattg aaaaaatgaa aaaaatttac tgattttttc aaataattta tacttggacc
     1021 aatatacttc acggtctagt gttaatatat taattgagag aggtgatatt atgaaaatga
     1081 aaattgaatt tagtacaggt tgtataccaa tatcttataa ttcgctcttt atgagtatta
     1141 taaaagaagc aataagaaaa tctaatgaag attactataa aaacatgtac tattataaag
     1201 aaaagaataa taaaaaaact aaaaatttta cattttcggt ttatataaaa aagtatagta
     1261 ttgaaggtga caattttatt atagaagata aagtaatatt aaatataagt actccagatt
     1321 tagaattggg ttttcatata tacaatgggt taatgacttc taaaaaatgt ttatataaag
     1381 actacgaact tacaagaatt agaatcgatt tatcaagaga aaagaaggta acagaagaaa
     1441 gggtactatt taatgcattg tctccaatct gtgtaaagtc taaagaagga aaattcttgg
     1501 agataactga tgatagatac atagaagaac taaactatat aactaatgaa gtggttaaaa
     1561 attatagggg gaatggatta aaaagaaagt tagaatttga aaatataggt ctcaaaaagg
     1621 tagtagttaa agagagttta agagaattta aaaaaataac aggtaaagag tatcaatata
     1681 ttaatggtta caaaggtaaa tttatattga aaggtgatat tgatgattta aatcttatct
     1741 acaatctagg aattggtttt agacgtgctc agggatttgg agatgtagat attttagaat
     1801 ggaggtgaga taaatgaagt taagagttta tagaggagat tggtttttta atatgggtat
     1861 agttggattt ttaaatataa taaagaaagc agataaacaa gctgaaatat ttattatgga
     1921 agattatatc gaatttgata gcttatttct tgaaaacttt catgagtatt attttaatta
     1981 ctttatggat gaatatgatg tatcaaaaag aattaaaaaa aatattgatt acagtataaa
     2041 ttttattaaa tctaagcctg atagaatcaa agatggaatt aagaaaatta aagatagtgt
     2101 gaaacaacaa aatgataaga ttaaaaaatt tgatgaagaa aaatttaaca tgataaaaga
     2161 gaagctagat agtatgtcta agataaaaag ttatgatgaa tttgatagtt tagaagcttt
     2221 agtagatgag actatagata tatttaaaat aaaatcaata aatgacaggc ttacagcaaa
     2281 tctttataaa tatgtagttc aagataatta ttttggacaa gttagttttt ttaatgttgc
     2341 taaggcgaaa ttagatttag atggattaaa acaggtaatg tttaatgatt atttaagaca
     2401 aattatatat tttggagagt tagaagattt attagaagag aatgactatg acaagttgaa
     2461 aaactattta aatgatagat taaatagtat agctaaggat ataaatgaaa aaaaagttag
     2521 taagtctagt ataaatacta tagaaaaaat tatgaaggaa ataaataaaa actttataaa
     2581 gaaaaataaa agcatagaag atataaaaaa gtatatggat agtttagaag tatgtgaaat
     2641 gtgtggttta tataagggaa tattagatga atactcagaa agtaattttg ctccacttgg
     2701 agtaagcacc aataatgcta ggaatatgtt ttggaatcag gcgtatgtac catcaatatg
     2761 tgatatttgt aagctaatat tgttctgtac tccagcaggg gctacttata caagaaagaa
     2821 ttatttaatt aatgaagaaa atgagtttta tttatttgtt aacatggata cttgtataaa
     2881 tgagcttttt gaaagaaata atagtttaaa agctcaaaaa agtgagtatt cagattccaa
     2941 agatgaaaat ccttttaatc agcttataaa aagtatagta gaagaaaata cattaaaaag
     3001 tgaatggcaa cttcgtaata tactttttgt ggaatttaaa gcaagtatag attctaaaaa
     3061 atgtaaaata aattatttta atattccaac ttatttagca aagttttttg taaaagaaaa
     3121 taaaaaaata caaagtatat atgattataa acttaaatca aatgtgttag atttaatttt
     3181 aaaaagtaaa gacttaaaac atttaattaa taacacttta aggaatatag ttaagagtaa
     3241 tttagaaagc aataataaat caaacatatc agggttatct tgtttcaatg ttgttcaatt
     3301 aagaacaata ttaaataact ataagagagg agtgtataaa atggactata aaaagttgag
     3361 aaagatttat gagtcaggtt gtgaaataca tgattattat attgataaga atgctaaaaa
     3421 taaaatagaa ggaataacat ataaaatttt aaatttaatt aaggttggta ataaaaatga
     3481 ttttatgcaa acaattttaa gaattttttc accaagtgaa aaaacaccac cagaagaaat
     3541 tttacagata tttgttgaag aagatttaga ttttgaatct gtagggtatg catttgtaac
     3601 aggattaatt tctggaaaat atgaaggaaa agataaacta ccaaacgaaa aggaggaaaa
     3661 ataagatgaa aagagggtta acatttacag taatagcaca ggctcaaagt ttaaactatg
     3721 gggaagggat aggtaatata tcagaattaa aaaaattaag tagagatgat ggaaatatat
     3781 atacatttgc atctcgccag tgtttaagat atgacatagt acgattagca gcagaattgt
     3841 ttaattggaa tttacaggtt gtcgataaag aaaaaggcac tattcaattt aaagacaata
     3901 taagtataag agaatcagaa gaaatggatt tatttggata tatgaaaaca aataaaaaag
     3961 atgagaaaga taaaaaagga ggttctttga ctagagaagc tactgtaaga ttaagtaatg
     4021 caatttccct tgagccatat agaagtgaca tggacttttt aaataataaa ggattagcag
     4081 atagaatagg agaacatcct aatcttgcta acatagagca acatttaagt tattatacat
     4141 atacagtgac tatagattta tctaaaatag gtaaggatgg agatatagaa cttgataata
     4201 aagagaaatg tagaagagta gtagaatttt tagaaataat aaaagtattg aatagaaata
     4261 ttagaggtag acaagaaaat ttatctcctc tatttgtagt aggaggagta tatgaaatag
     4321 caaatccatt tttcttgggt agaattaaat taaaaggaga taaaaatgga tttaaaataa
     4381 ataagcaagc tatagaagaa gtaattcaag gtactttttt aggaaaagat ttaaaagaat
     4441 ttacctatgt tggaatggta gatggggtat ttataaataa agaagaattt aagggattgt
     4501 ttgaagataa ttttttaagt gtagataaat tttttggaca actagttaaa gaagtaaagg
     4561 aatattatgg ggtgaattaa tatgaaggtt ttgaaattag atttatttca agaaactgca
     4621 tgctacaaaa aaccatttgc tatgaagatt acagagacat atccactgcc tccatattct
     4681 acaataaatg gattaattca caaaatatta aatgctacag aatatatacc atttaatata
     4741 agtgtacagg gaacatatga aagtatattt aataattacc agacaacata tttttataaa
     4801 aaagatagta ttacatctat gccaatgaat agtcatatgc tattgaatgt aaatttgata
     4861 attcatatag gtggggattt tgatttattg gaagaaatat atgatagttt attaaattat
     4921 gacgagcact tatcattagg tagaaaagaa gatttagtaa gaattaatga tattagattt
     4981 gtagaagtca ataaatttga agtagatgag gatatacaat tagatgatta tgaaaattat
     5041 aagttatcag aatgtaatat aagaatgcct atatatatac caaaaacaag tttacaagat
     5101 acagatatag atggtataag ttacagactc aataattact atgataataa tgctgtggaa
     5161 gataaaaaaa gggtttggaa taaggtagat agttattatg ttgaggatgg aaatactata
     5221 tcaattggag atatattatt agataatgaa ggagatttat tatattttaa taatataaat
     5281 taggagggag attatgttat atgctaaatc taatccagtg gaaacactta gagaacatac
     5341 tgatgaactt ttaaaacaaa tgaatgtatt aagagaaagt tatggaaaaa atataaatag
     5401 cttagatttt ctagaagagg agatattttg gcaattactt gactttgtta tagaatttca
     5461 tgatattgga aaagcatttt caccgtttca agagttaata aaaagcagaa tggatactaa
     5521 aataaatgaa cctaaaatag taacttattt agaaaataat gtaggccata attatctttc
     5581 tcctgcattt attgattata gttatataga caggaaaaaa aataaagaac ttagagcagt
     5641 attaaatcaa gttattgtat atcatcatga aagagatatc tttatagata aagattttaa
     5701 aaatttaata caaaaaatat tagatgaaga tttaataaat aaagtttatg aactacagca
     5761 tgaatttaaa gttagatatc caataaaaac agaaaaattg agtaaagtat atctacaaag
     5821 tgtagaaaaa agaatagata aaaatcacaa gtactataat ttatatatta tgttaaaagg
     5881 aatactacat agactagacc atagtgcttc tgctcatgaa gttgtggaat gcaataatgt
     5941 tataaatata ggagaacaga cagaaaatta tttaatgaaa gagtttggta gtttgagaga
     6001 ggctcaatca tttgctaaat ctaatagaaa taagaatata atactgattg catctacagg
     6061 aatgggaaaa acagaaactg ccttaatttg gatagataaa gacaaggcat tttttacact
     6121 tccattaaga gtaagtataa atgcattatt tgatagagca aaaaatatag ttggtgttgg
     6181 agaatcaaat gatacattct taggtttgtt acattcaaca gcaatagatt atctagaaga
     6241 aagtaatcaa gaaaattcaa gtgagattgt agatttagca aagttattat cttgcaaact
     6301 gacattttct acaatagacc aaatatttaa atttcctttt ttgtatagag ggtatgaaaa
     6361 agtgtactca acattagcat attcaaaagt agtaatagat gagatacaag catattcacc
     6421 agaaatagca gctgtattgg taaaaggtat agaaatgata cataagatag gtggcagatt
     6481 tatgataatg acagctacta tgccaaccat atatatagat gaattaaaaa aaagaggtgt
     6541 aatgaatagt aacttagctg aattgacatg taatacagaa aaaataagac attgtgtttc
     6601 tattgtagaa aattcaatag atgaaaactt aggtaaaata atacaaagtg gaatgaataa
     6661 aaaagttctt gtaatagtaa atacagttaa aagtgctgta gaaaaatatg agttaataga
     6721 agaaatagtt aaaccaaaag gaatagatgt caacttaaat cttttacatt ctatgtatat
     6781 acaagaagat agagcaaaat tagaaaaata tataaaagaa tttgccaata gtgatagaaa
     6841 tggaatttgg attacaacac aattagtaga ggcatctctt gatattgatt ttgatgagct
     6901 tcatacagaa aattcaacac ttgacagtct atttcaacga tttggtagat gttatagaag
     6961 tcgtgagtat gaagaaaata gcccaaatat atttatatat acagaaaaag ctacaggaat
     7021 aggtagtatt tatgataagg atattgtaga aaaaggactt gagctactga aaacttttat
     7081 aaatggaaaa gaatgtgtga agatgaaaga aaaatataag gtagaaatgg ttaagatact
     7141 atactctaaa gaaagtctag aaggtacagc ttttgaaaag agatttacca gtgctttaaa
     7201 tattttagat actataacgc catatagttt aggttctaaa gatgcacaaa atatacttag
     7261 aaatattgaa ggatatacag taattccaga ggatatatat aataaaattg aagaaacttt
     7321 aatcaaagat tatgaagagt tgggacaaga gcttataaat gcatatagta atgatgatag
     7381 acaattgata aataaaataa agtctaagag aaaaaaagca agaagagaga taattaaaaa
     7441 aactgtaaat ttaccaatat ataaagctaa acaaaatgta attgacatac aggtgaaagg
     7501 tcttgaagat ttaaaaatac ttttatataa atatgatata tacgaaaata agcatacaaa
     7561 acagatattt ggtaaaggtg tgcttataag taatgaaata gaccaattta tttgattttt
     7621 atattaacaa tgtggctaaa atttactaaa gaaggtgatt ttgtgccaat agatttagaa
     7681 gtattaaaag ttcaaggtgt aaaaataaat tattattatg tatgtaaaag aaaactatgg
     7741 ctattttcta aaggaataac catggaacaa aatagtagta gagtattgtc tgggaagata
     7801 gtacatgaag attcatataa aagaatgaaa aataaagaaa tattgattga tgatatcttg
     7861 aagctagata taataaagga tgagtatgta aaagaagtaa aaataagttc aaagatgaaa
     7921 gaagcagatg aaatgcagtt atactattac ttatactatt taaagaatag tatgggtata
     7981 gagaaaaaag gtactataaa ttatgttaag gaaaagaaac aagaagaatt gatattgaca
     8041 gaagaaaaag aaagaattat tgaaaacaca cttataaata taaatgaaat aaatatgcag
     8101 ttatctcctc ccaaaattga gaaaaaacat tattgtacaa aatgtgctta ttatgaattt
     8161 tgttttgtga aggaggagta acaatgtata aagactatta tattataagt aatggggata
     8221 taaaaaggaa agaaaatacg atttactatt acaatttaga aggtgagaaa aaaatattac
     8281 cagtagaaca agttgatgat attcatatat atggagaagt agatttaaat acaaaactta
     8341 taaattacat aagcaaatat ggggtgatgc ttcatttcta caattactat ggatattatt
     8401 caggtacata ttatccaagg aagaaaaatg tatcaggatt cagtttagta tgtcaatcag
     8461 cctgctattt agataaaaat gaaagattat acttagcaaa atcctttgtg gaaagtgcat
     8521 cataccatat tttaagaaat atgagatatt acaaagttga tgaaagttta attgatacta
     8581 taaaggatga actaaatgat ttgaatgatg tcaaagaaat atcagaactt atgggtaaag
     8641 aaggcagaat aagaaaaaca tactataaat catttaatca aatattaaaa gatgattttg
     8701 aattttataa aagagaaaaa agacctccca aagacccagt aaatgctctt atgtcttttg
     8761 gaaatagcat aatgtatacg aatgttttaa gtgagatata taagacacaa cttgacccta
     8821 caataagctt tttacatgaa ccatcaacaa agagattttc tttaagttta gatattgcag
     8881 aaatttttaa gccaattata attgacacaa taatttttag cctgattaat aataaaagaa
     8941 ttaataagaa tgattttgaa tatcaagaca aaatttgtta tttaagtgaa aaaggaaaga
     9001 agaaattttt gcaagaattt gaaaataaga tgcagacaac tataaaacat agaaatctaa
     9061 atagaaaagt ttcatataga atgtttataa ggttagagtg ttataaatta attaaacatt
     9121 ttataaatga tgaaaggtac aaagttttaa aggtgtggtg gtaagtatgt ttgttattgt
     9181 tacttatgat attgttgaag caaggtcgtt aaatagaatt agaaggatac ttagaaaata
     9241 tttgacttgg acgcaaaatt ctgtttttga aggcaatatt actgaaggaa agttacataa
     9301 atgtatttct gaaatagaaa atattattga taatagcgag gattcaatct atgtttatga
     9361 gataaaaaat cctaattcaa ttaaaaagaa atgttatggg attgataagt attctgatga
     9421 aatgtttata taggtttgca gtgagcgata tttatgctaa aataggtgtt aacagttgga
     9481 atataaggga ttgaaggtgt atgataattg ttatcaattg cactactgct cgctcactgc
     9541 aaattttgat gtttttattg aattataatt gcttgattga agtgttttca atgtattcaa
     9601 atatacctat tttggggttt tatattaact aagtggtatg taaataattt tttcggatat
     9661 ttaataattt attttaaatt tagttttata ttaactaagt ggtatgtaaa tctcaacagt
     9721 atctacaaga acttctatat cttctaagtt ttatattaac taagtggtat gtaaattaat
     9781 ttagggtaac ttttatatta ttttcttcta tcgttttata ttaactaagt ggtatgtaaa
     9841 tttggttgat atagatatta gtcctattat ttctgcttgt tttatattaa ctaagtggta
     9901 tgtaaataaa ttagataatt tataagtcaa taaaataagt ccaagtttta tattaactaa
     9961 gtggtatgta aataaatttg taatattata taatcatcct aaaacaaaag gttttatatt
    10021 aactaagtgg tatgtaaatt cgaatgctat aattttaata tataaaataa atggagtttt
    10081 atattaacta agtggtatgt aaatatggat tttagtcgtt tttaaatttt tctcgtaata
    10141 gttttatatt aactaagtgg tatgtaaata ccattcattt atatttttat ctgtatctct
    10201 tagccatgtt ttatattaac taagtggtat gtaaattaag ttttcttaaa aaagtacttg
    10261 ctttaaatat gttttatatt aactaagtgg tatgtaaatt ttattttctc tttattagtc
    10321 attagttttt gccttcgttt tatattaact aagtggtatg taaatatgaa gaatttgcga
    10381 aactaataag aaaagatatt gagttttata ttaactaagt ggtatgtaaa tctttcttta
    10441 tcaaagtaag ctaaatttag ttcctccgtt ttatattaac taagtggtat gtaaatcgtc
    10501 attacttttt attgcttcca ttaaatttgt tcgttttata ttaactaagt ggtatgtaaa
    10561 tatcgcaaga taggctaaat ctatcaagga gagttgagtt ttatattaac taagtggtat
    10621 gtaaatgact ctgccatccc tgtaacaaac agtcttaccg caagttttat attaactaag
    10681 tggtatgtaa ataaatattt tacgattagt tgatgctata attctattag ttttatatta
    10741 actaagtggt atgtaaattc ttttgattta gcgttgtttg tccggaattt taaagtttta
    10801 tattaactaa gtggtatgta aattcgggct agaatgtatt ttaaacccta gttcattgaa
    10861 gttttatatt aactaagtgg tatgtaaatt ttctaatatc gctatttaaa ctcaatgctt
    10921 catttgtttt atattaacta agtggtatgt aaattcagaa caaattaaat atgtttcgtt
    10981 ttccatgtaa ggttttatat taactaagtg gtatgtaaat agaacttttt tatattagaa
    11041 gtacttgaca tgattgccgt tttatattaa ctaagtggta tgtaaatctt gataatattt
    11101 cagcatatga tactgaagat ggttttatat taactaagtg gtatgtaaat ttgccaatgt
    11161 aacatcttta gatattacag tatcattgtt ttatattaac taagtggtag ataagtagaa
    11221 tattagcaat atcaacgagt atttagaaac ttattttata ttaataaagc agtatataaa
    11281 attgtagaat caacaatagc atatactaaa acatccacct tatattaact aaatcatatc
    11341 taaataaaat aaacttacct ataaacatta taaaatcaat acaaaaatga ggtgaaataa
    11401 aatttatgat aaagaaatta aacaataaag atataaataa aatcatggaa atatgggaaa
    11461 aaagtacaat caaagcacat gactttataa gtaaagaata ctggcaaaat aactataata
    11521 ctgttaaaaa cgaatatata cctatatcag atacatttgt atatgatgat ggagatgaaa
    11581 taaaaggatt tataagcata atagataaaa gctttatagg agctttattt ataaagccca
    11641 aataccaaaa tctaggtatc ggaggtaaac ttttagatta tgcaactaaa aaatataaaa
    11701 gtctaagctt agcagtatat aaagataata aaaaagcagt tgtgttttat aataaaaaag
    11761 gttttaatat agtaaaagaa caagtaaatg aagattcagg atttaaagag tacataatgg
    11821 aatatagtaa ataatatgat tacattctat taaaaggata attaatttat ttgccatttg
    11881 attttttaag agtaattttt aaaatagact atatgaagat aaagatattt attatagatg
    11941 taagttaatc agaattgata tagctacaaa agaggaaaat aaaattgtat ggtgtatttc
    12001 agatttaaca aatttactat ttaaagataa taagtttgat ataatattaa agatactttc
    12061 acctataaac tatagggtat ttgaaagaat tttaaataat tatggaatgc taataaaggt
    12121 ttgttaaaat ttaataatta ttagattata gaaaattgcc atgaaattag ttcatcaaga
    12181 actagtttca tagcaatttt aattcttata agtgtattta tttttacaga tttaaaaaac
    12241 ttatacagta tctaataatg taatcttatt actttagcct ataaatattt aaatcttaaa
    12301 atgttctctt tgagataagt ttatttcaga gtcacaattt ccacaacagt aagatgttga
    12361 gacatcttta aatttttcag tattctcatc aaagttcatt tttttctttg caataattcc
    12421 taccttagtt aaattagaac cacaattatt acagttttga attttgcata ggttatatag
    12481 tttatcaagt gtaatatctt ctaataattc atcacaatta caacatctga tagaagaaac
    12541 ttcactacac atttcaatag gttcagcttc tttagaagaa aatttatatg ttatgtcatt
    12601 tgatacttta taacctgtat caaatatatt agaattacaa cttggacata agtactttgg
    12661 aagatatata tctttttttt caaaagtatc actactaata ttacagttta attcatctaa
    12721 aattggtctt tcatctaggt tattaccttt atttaagctt agaagataat tataaatttt
    12781 tttatcttca ttctgttttg atgtatctaa caaatgctcc attatattag tgtatttttt
    12841 gttttttgaa ggcatgttta aatccagata attgttttca atagcaaagc atactatatt
    12901 gaaatagtta tatttaactg caaaaaataa taacatttca tcaaatactt tatctattat
    12961 tttgtcagaa atacttatcc aaaaatctgg tgactctaag taaactttcc tactaagttc
    13021 atctaactct tcatctatat tatttatatt attttcatta actttcatat catcacttcc
    13081 ttttaaatat cttgtgtata aactatttgt tactattttt tatataaaat aaaatcttat
    13141 ataaaaatat atcatattat aatttacaag tatagtctaa atagagctgt ttttaagcaa
    13201 agttttataa atgactatta aaatataaag taacagtata aagtttactt ataaattaaa
    13261 tgtaaaccta aatgcttata atagttgaca aaaaaacgtc tttattttat actaaaacaa
    13321 agctttaata gaagctttgt atatgtacat ataaactaaa tgaaataaga catatgaagg
    13381 gaattataaa aatgaaaaat actaaagtaa atattcaaga tttaactaaa atgtcaatat
    13441 gtgtagcatt attgtgtata tcatcttaca tatatatacc attgccattt actccagcag
    13501 gagtaacagc acaaacaata atgataaatt taatagcttt gattttaaca ccaagacaag
    13561 catttagtac agttggtgta tatataatga taggtttaat tgggattcca gtatttggtg
    13621 gaggtacatc tggtattgga aagttattaa gcccaacagg tggtttttat tttgggtttt
    13681 tgtttgcagc actaattatt agtttattaa aaggacgaaa taatgatatt aagagatata
    13741 tactaataac aatttttgtt ggaatgccta ttatatattt tatgggaaca gtatttatgt
    13801 gctattttaa tcaaatgaca gtagaagcag cactttttgc agcagtagta ccatttttaa
    13861 ttggagatac aataaagtca gttattgcat cttttttagg cactaaactg aacaatgtac
    13921 tcagaagaaa tctatgataa atctataata taaggaaggg tgtaatgtat gaaggaagtt
    13981 tttatattag gaggattgag aagtcatata ggtctaaaaa atggaatttt tcaatttgtt
    14041 caacctgaat tactaggagc aagtgtttta aaagatttaa ttaaaaagta tgaaattgat
    14101 aaaattgatg agattatatg tggaaatgca gttgggacag gagggaatat agctagatta
    14161 atgactttaa cagcaggagt gtcaaatgaa gtacctgctt ttactgtgga tatgcagtgt
    14221 gcttctgcta tgatgagtat agacatagct ttttcaaagg ttaaatctgg tcagtgtgat
    14281 ttaattattg caggtggttt tgaaagtagt tctctacaac caatgcgcac atatcataag
    14341 aatgataagc gatataatac aaataatcca aattatacag ttgctcaatt ttctcctgat
    14401 gataatagcc aaaatagtat gctcgaaggt gcggaaagag tagcagagtt atatcaaatt
    14461 gagaaagcag acttggattt ttgggtaaag gaaagtcata aaagagcaaa agaagcaaga
    14521 gaggaaaaaa tacttgaaga tattatatct cctataaata atagtaccta tgatgaaggt
    14581 atacgtgata agatgagtca aaggttatta gataggatgc catcaatttt aggaaaagaa
    14641 actattacaa atgcagcaaa ttcatgtctt attaatgatg gagcttcatt tattataata
    14701 tgttctaaga agtatttaga acatgtaaaa aagaagccta aagcaaaaat tattaataca
    14761 tgcacaatag gaacagatgc aaccttaagt ccaacatcag cgatacaagc aatggataaa
    14821 cttttagaga tagaaagtct taattattta gatgtatctg ctgttgaatt taatgaagca
    14881 tttgcagtta tagatgtgtt gtttcaaaga aaatatccag agttaataga tagatataat
    14941 atatttggtg gagctttagc gtatggacat ccatatggtg cttcaggtgc aattattgca
    15001 ttacatcttt taaaagcatt agaaaagact aagggtagat atggaatttg ctctatagct
    15061 gcagctggtg gtctaggttc agctttactg cttgaaaggg tgtagattat gaactattat
    15121 gaacttttaa gaataaaaaa agagaggcat aaaaataaaa attttttaat tatagatgga
    15181 gaaaaatata cttatgaaaa tatattgagt tatagtgagg aactaggaaa acaaatttct
    15241 ttaggtgaaa atatcccaat tttaatatat tctaaaaata taatgtttca gttgattagt
    15301 ttttttgcta ttaattattc aaaaaatatt cctattattt gtcattataa tctttctaaa
    15361 aaagtattag atgatatttt attaaaaaat aatatttcaa tcattatatc tgatgaatct
    15421 atggacgtta ttgatttata tgatgataac aataatgaag tagcaaaaaa agttaatttt
    15481 tctattttta atcctaaatt taatatatat atgtatcaat ataagaacct tataaattat
    15541 ttagataaaa gtatttgtat gggagcttta tcttcaggtt ctacaagtgt tccaaaggta
    15601 ttatatagaa catatgagag ttgggctgga ttttttccta tacaaaatgg tatttttaat
    15661 atctctgggg aatcaatctt gtttgttaat ggaacactta gttttacagg gaatctaaat
    15721 tctataatgt cagtattata tgaaggaggt agtattgtaa taagttcagg tcttaattgt
    15781 aaatcatgga taaggataat aaaacaatat aatgtaacta acatatacct tatacctaca
    15841 aaacttcaac ttttggttaa acacttaaaa gaaccagtac tcaaagttgt aagtattttt
    15901 acagggtctc aattattatt tgaagatact gcaagaaatc taaaaaaata tatgccaaag
    15961 tctgaaatta ttttatacta tggggcaagt gaattaaatt atattacata tttatgctat
    16021 gatgaactaa ttgaaaaacc tctaagtgta ggcagaccat ttccaggaat agatatatat
    16081 attagagaag gaaaaatttt tgtgaataca gaatatgcag tatataatgc aaccaaacct
    16141 tattctgtca atgatattgg atattatgat aatgatggat acttaatatt tgaaggaaga
    16201 agtgatgaca ttttaaatat tggaggattt aaagttagtt ctactaagat tgaaaatgaa
    16261 gttaaaaaaa ttcctcaaat tgaagatgca attgtattgc cgtactcaga cactataaga
    16321 ggaaatcaaa ttgtattatt tgtaataact atagacaaaa ttacgaagaa agatttgttg
    16381 attaaaatga aagataatct aatgaaaaat gaaatcccaa agaaaattat ctttttaaat
    16441 tcatttccat atacctcttc tgaaaagata gatagattag cattattaaa aatgttataa
    16501 gtataatatt tagtaatttt agtgaaccaa tgtattgata aaaacatatt gtatatagta
    16561 aaggaggctt acaatatgtc aaatcaatac gatataactg ttattggggg agacctgcga
    16621 caagtgtaca tggtaaaaaa actaattaat aaagggtatt ctgtagtcac ttatgggata
    16681 tcaaatgaaa ttataaatgg aatcgttgga aaatcaactt cactagctga agcactatcc
    16741 aaaagttcca ttattttatg tccaattcca tttacaaaga atcaagttaa tattgaaaat
    16801 acggatgatt gtcttgatgc tactattgat aacttgctaa ttaatttatc tcctaatcaa
    16861 atattatttg gaggtaacat accaactaaa gtttgtaaat tttgcgagca acactctatt
    16921 cagatttatg attttatgaa aatgaatgat gttgctattt taaatgcagt tgctacagct
    16981 gaaggggcta tagcagaagc tattaaaaga agtataatca atatacatca aagtaactgt
    17041 ttagtattag gttatggaag atgtgcacaa atacttgcaa aaaaattata cgctttggat
    17101 gcaaatgtat gtgttggcgc aagaaataat gatgcaagaa gtacggctaa tgcatttgga
    17161 tattccagta tttctttaag tcaacttgat gaaaaacttt tacaatttga ttatattttt
    17221 aacaccatac cagagtgtat tttaacgaaa gaaaggttag aaaaagtatc acaagaagta
    17281 actattatag atatagcttc ttctcctgga ggagtagatt attctgttgt taaagaagca
    17341 gggattaatg cgactctttg ccttgggctt cctggtaaat attcaccaaa gacatctggt
    17401 gaaattcttg ttaacgctat agaaaatatt ataaatgaaa gaagggatta gaaatgagac
    17461 ttgaaggact tacaattgga gtaggattta ctggttcgtt ttgtacttat gataaaatat
    17521 ttatagagtt agagaatttg gttaaagaag gagctaatgt acacactata ttttcagatg
    17581 tatcacaaaa tatcgattgt agatttggaa attctgaaga gtttatgaaa aaagcatatg
    17641 aacttacagg aaataaacct atagttacga ttgaagaggc agagccattt ggacctaaag
    17701 gaattgctga tattataata atagctcctt gtactggaaa tactgctgca aaattagcaa
    17761 atggtattac agattcacca gtattaatgg cagcaaaagg tcatcttcgt aatgataaac
    17821 cactagtaat atcaatatca acgaatgatg ctctaagctt taatttcaaa aatattggca
    17881 ttctccttaa ttctaaaaat atatattttg taccttttgg tcaagataat tgcaaagcaa
    17941 agcctaattc tatgattgca catactgagc taataattcc aactatagaa cttgctctag
    18001 agaacaaaca gctacagcct gttataaaaa gtccacatca atagaattgg ttcttataat
    18061 attatgtatt agatacaata ctagcaaaga ggctgtctca aaatagagag aagcctcttt
    18121 ttcttgttga aatgatgaaa atatatttaa tttcatacaa aaaaatgcct catggactaa
    18181 aaagtctatt ttgagctaat ctccgtaatt tttgctatat taaaattatt tacttaatcc
    18241 aatttttaaa ttagaattta tatcgttttg actcttcaaa tatcaatcta actgttgttg
    18301 atacaaaaga agaggacata attaaaacaa atactgatag tcctctaata aacaaattat
    18361 ctacataata agttactatt ccaatacctc caatcgttaa aattacactt ataatcaaag
    18421 aaaaaacgct aattgttttt aatttttcca tgcttatcct ccttcttata aacttcaaat
    18481 ttatctatat aatattaaat atattttatt tcatattata taaaaatcat gaatatatat
    18541 ttttttaatt atactatatg ttgtaaatgt ttgtacattt aactatattt actttaactt
    18601 gttaattaag ttttaatttt cattttcaag gatttttatt tttaaacttg atagagtatc
    18661 atattaaaaa ttctttttat aaagttttat ttgcaaaaaa tacaaaaata taaacgttaa
    18721 aaaaataacg ttatccttaa gtttttagat gatttcatta gtgatttgcg taaaaaataa
    18781 agtgatatct agttaaatta agtatttgta aagctagata ttattagtag aaat
//
LOCUS       DAJMZY010000082        18708 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.082, whole genome shotgun sequence.
ACCESSION   DAJMZY010000082 DAJMZY010000000
VERSION     DAJMZY010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18708)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18708)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18708
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.082"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            complement(<1..525)
                     /locus_tag="OE968_002709"
     CDS             complement(<1..525)
                     /locus_tag="OE968_002709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB-like nuclease domain-containing protein"
                     /protein_id="HCP7219979.1"
                     /translation="MEYKSPVYGIIAVPIEKIESNDYNPNAVAPPEMQLLYKSIKEDG
                     YTMPIVCYYNEEKDKYIIVDGFHRYRVMLENEDIYDRENGLLPVSVIDKSLDERMAST
                     IRHNRARGSHNVDLMSKIITELCEIGKSDEWISKHLGMEVDEILRLKQITGLAYLFKD
                     KEFGNAWIPFGSDIE"
     gene            complement(543..1856)
                     /locus_tag="OE968_002710"
     CDS             complement(543..1856)
                     /locus_tag="OE968_002710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3440 domain-containing protein"
                     /protein_id="HCP7219980.1"
                     /translation="MDKRYLESDVFEAFQERLSYLFNEFDYIYVSFSGGKDSGLLLNL
                     VLDYKRKNNISSKIGVFHQDFEAQYSLTTEYVEKVFEDNIEDIEPYWVCLPMATRTAV
                     GNYEMYWYPWDDEKEELWVREMPVKEYIINQKNNPFTYYKYKMRQESLAKQFGRWIRD
                     IHEGAKVVCLLGTRAAESLQRYCSIVNKQHGYKGKCWITKEFKNVWTASPIYDWEIED
                     IWLAHYKFDYDYNKIYDLFYKAGVAPRKMRVASPFNDSAKESLNLYRILDPDVWVKLV
                     ARVQGVNFTSIYGKTKAMGYRSVKLPYGHTWKSFTYFLLDTLPENIRNSYIKKFSTSI
                     EFWQNTGGGLSEIVIRELLRKGYKIELNGVSNHTKDKKSRVIFLDDIPDDTDDIKFTK
                     DIPSWKRMCYCILKNDHMCRFMGFGPTKEQRIRTEYIKKKYEKIH"
     gene            2211..2651
                     /locus_tag="OE968_002711"
     CDS             2211..2651
                     /locus_tag="OE968_002711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3788 domain-containing protein"
                     /protein_id="HCP7219981.1"
                     /translation="MYERMLDKSNKPCLSQIIEYIGKDGYARLCKLETYLKTQYNLSR
                     ELRFPFGNNYGWGYKYSHKSFHLFYAFFEKGAFTVLIQIGDKQVPAVEKTLVALTPKA
                     KELWVTRYPCGNNGGWIKYRILEDADLLDIIQYIRAKKSPPKQN"
     gene            complement(2836..3024)
                     /locus_tag="OE968_002712"
     CDS             complement(2836..3024)
                     /locus_tag="OE968_002712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219982.1"
                     /translation="MNKNNNLVIICMFIGMILGMAIGCAIGISKGNVGITMCYGLIFG
                     MIIGICIGTVIKNSNKKE"
     gene            4071..4466
                     /locus_tag="OE968_002713"
     CDS             4071..4466
                     /locus_tag="OE968_002713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219983.1"
                     /translation="MNILKMKKTGIFLGGVLFGTVGVKILSSDCVKKTCTRATAGALK
                     VKDSVLETTTKIQENVEDILAEAKEINEQEDLSTSKVNVVQDTLKCEQEVLKTETIKT
                     VEDTNSNSIKCEEIKDNVIEEKNSTCTTE"
     gene            4509..6608
                     /locus_tag="OE968_002714"
     CDS             4509..6608
                     /locus_tag="OE968_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HCP7219984.1"
                     /translation="MNFYIKHEIRGRIRFDLQLGKLNNKQSDTLLYYLTSINGITKAK
                     VYDRTGDAVIYYNGEREYIIREITKFSFNNSKIENLVPEHTSRELNNYYRDKLANKLL
                     VKSISKIFFPKSLRFFLIGLHSIKYFKKGLSSLLNKKIEVSVLDATAIGISIFRKDIN
                     TAGSVMFLLGIGELLEEWTRKKSIDDLAQSMSLNIEKVWLRKGDTEILIPISEIKEGD
                     LVSVTMGNMIPLDGVIVSGEAMVNQASLTGESLAVNKKEGSYIYAGTVIEQGNIVMCV
                     KEKAGTTRFQKIVTMIEESEKLKSSVESKFEHLADTLVPYSFLGSILTYAITRNPIKS
                     LSILMVDFSCALKLSIPISVLSAMRECNNNNITVKGGKFLEGVACADTIVFDKTGTLT
                     KAQPTVSDIITFQNYNKEDMLRLAACLEEHFPHSIANAVVYEAEKQGLSHKEMHTEVE
                     YIIAHGISTKVDDKKVVIGSKHFVFEDEKCTIPDGEEDKYNNLSDEYSHLFMAISGKL
                     SAVICINDPLRKEAKYVISNLRECGIKKIVMMTGDSEKTAKSIASKVGVDEYYSEVLP
                     EDKANFVKSEKLKGRKVIMIGDGINDSPAISESDVGIAMSEGAEIAREISDITISADN
                     LNNLIVLKQISNKLMKRVDLSSKFIIGFNLGLILLGVGGFVRPSTSAFLHNASTVGIS
                     LNSMTNLLENTNTYNYH"
     gene            complement(6833..12043)
                     /locus_tag="OE968_002715"
     CDS             complement(6833..12043)
                     /locus_tag="OE968_002715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosome-binding GTPase"
                     /protein_id="HCP7219985.1"
                     /translation="MANKLYSEIVNLLEEGRDELRKYDLKEKSILLFLGASGVGKSTC
                     INYLKGCVMEEKTDEETGQIYITAKDSAVEIGNGVYSKTLCPEVVDIANRDFSLCDCP
                     GFFDNRGAEYMIAGAMLVRETISTSSKVKGMVVILDYQSLLDSRHTLLIETGKNLKDM
                     LGDYAKYKENFFFLINKIPKTLIGNVTEEKIRNILEKAKEDLDSQEKDYDGCKELVYL
                     LNVALSDGVSIKLCNPLDKQPEKLLDEMKNLPETFEKTDLGLMLTASCKIEIQKAVDV
                     TYKDLEKLLVPYIESVKKGMEDSISILSSINSLKDKKIQLDKMYTDLCSRTNNMKEIM
                     EFVQELSYGDGVQKVNILEETRLLLELNSYCSETHIVGLSELLKSLLKNTLEDTLKDI
                     KYWIAEEEYREEEAKKLEDAEYRIEKIQSCTYIKSYEKENVLSIYIPIPKVNLSDLTK
                     IISGYQLNILSSIYMYGDCELKIDCNMEKEVFSGKNIVLLTEKLHIPEGTYSINVSGK
                     DAEKLVGESSIYDGMNGRNGNNAGTSGDIILSFKEIEKRGELKLYVDGGRGGNGQDGK
                     KGDTGITGEAGANAKIGSKKESKEFANVKGTKYYVVKAEKGKQGGTGGTGGNGGNAGL
                     GSKSGQVYLLGKAPLLKSAISKKDGNHGLAGKGGSGGAGGAGGLGGIRGIYEETIRYI
                     GTSPPMDNSDRNYYYFDRYVFNHALNQKQAADDGEKLNALYEEHKDWIISKREDSGSA
                     GAEGTAGHSGDALKEKELLKQEYSLSIDTFFYEFFERFGFSGIKGYRNLRLLCAVGIL
                     EADILELSHIYEIFHAVEKIEMQLNREILQKYYSFEKKNKAVLSLDDMNTKKEFYKEA
                     KEIYEYLINKLMQSDRIESFVGKNQNFSEWSMILFALEQKTAFYVQMIEESEIGGNRV
                     TDIRSLTDYLDKTLRELEQGKKDELKEGYFNTYKESILTQIESGNQQIEVLKNELENK
                     MLSVNAKMNLLIQEIIKMKEDEQEDIEELKKKQAKLEEQMKTQLILSGIQSALSLLTA
                     FSGVGQACLGAFDSAKSLKENLSAKEEEYKWTNRMVNFSDFKLDSDGMRFVLGEQLSE
                     DRKNALDKMTYNLAGVDEERRTKFDQIKEIIVKSIDDDNYADKADDIQRAKEGLSESE
                     YKEIYTKIQKKEIGMLEANYNNKQQKDKLAALEKSKQAIERQQKTSKIKNALSIGSSA
                     CSLINTAISGVNNCLNVKSSFESKIEVVKEAIKDKENNIKKLDELNTQMVEFKDKTLK
                     ESVIPFVEKFDSTVKNQDIFENEISKLKMKEVLTELSTKFGSLKMENSEEISIIFKKV
                     QDMMETQIIITDKIDKKKDNLAMGELIYQMSDSGNQMNEYQKKLIHQIELNQVRYLCQ
                     VEAAAFQLWTFPFGSNIVNILNRCHVGITEDENEVINQAKEQNRQIREFLDQDAYQWQ
                     KTDNHILKVALTGSLDGKSRVGFENTYSLYDCNEEEVKKLLTGDEISFEVPLNKNFDA
                     IKYVTMYANIPNLRRNILEDSLKVKVHIHLYDSGYFSLYDDKKDVYYQYVFPQNYINI
                     THGLDVKYNDSDSINSIWSSVEDKGIEKFKNAGLNSGRSPYSMAKISLKAHFNKKLSY
                     DSLTNEQKKKLESYFDKPSKYAWSDSIDILKSLGYIDFKGILSKSWYEIKKDIDSDGE
                     IMKHFSILQVDLLERIIYEQTSILKENIPNLTIELVGCGIYVESEFNYLKQNDLKCYE
                     ERLVENTIIG"
     gene            complement(12058..14553)
                     /locus_tag="OE968_002716"
     CDS             complement(12058..14553)
                     /locus_tag="OE968_002716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HCP7219986.1"
                     /translation="MPENNNQLLEEITLLLNEGKVAINKAENQNLILILGGTGCGKST
                     AINYLAGCVMMEVEDEDTGISYIDCLDPVAEIGSGAVSQTLYPNIVNMRKPIEGMDAK
                     LCDTAGFSDNRGVAHDISAAVSLGEVFKNSASICAVIVLIPEADILDSRLTKVLDLFQ
                     QLNMCLHKENFKGSITFFISKSFLGRTEKQIYNVIKRKYEQLCENLDSNIEEKAWLFE
                     ELLKDNGKNIHLCKPLASDEREGLLKQVLELDEVKDKTSAFQYPISADARLVLDTLIK
                     EIQNNIVSSLEDYVKAYTEDFINIIGSITMIQEIAKYDEVVKVFKNWLESTTSLTIER
                     FINVLAKQSGLFLQDSCMKLQNKIKGNLDIIDALSKYTEHGTGEILLPSVHMEFIIEK
                     ASKKIMEQNFIIIRKNLEKVLVSYEVQKQVFTLPNREKLMEVANKKDYVYSVSDFNSI
                     LTNVTVTQNEELEDSITRLSAYGEEGNEIIREFIGKYILNPFIVKTININDKKGIEIR
                     ALIPNLVISSVLEYFKNRKVDDNVSTFMFFAKDTIYMDDNLGMNFASEKNIILASNNL
                     DVGSNVKINVSGKSGELVDNSMYGKNGEDGRDAGNIYLYIKEEIRNYRLTLIANGGNG
                     SKGIDGENGETGASGSNGADAGYTSYFHGQMFKGYFEKGTSGKKGEKGGAGGNAGRGG
                     NAGKKGNIYFISDSEEQKNRIINHCDITVKDGEAGPNGRPGLGGYGGSGGYHGYNTLS
                     FSPSGIDKTVYYTGYFTSWDYKLDSIIKYHIEFSGGSWNEGKTGPAREYAEYGDRGDN
                     GGFNAPNTKLSTAVSKVEENLIKEKYQGYCSEI"
     gene            complement(15236..15523)
                     /locus_tag="OE968_002717"
     CDS             complement(15236..15523)
                     /locus_tag="OE968_002717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219987.1"
                     /translation="MRLNVTKQNTIEVENSRKEDVYFVIVDNVFFERQGDVFNSITNN
                     NLNNYDVKILPTDNVFLELKITSTKDLEPVFIVVEDRQYNHGSIMFKPVLV"
     gene            complement(15543..15818)
                     /locus_tag="OE968_002718"
     CDS             complement(15543..15818)
                     /locus_tag="OE968_002718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219988.1"
                     /translation="MSLFVGGWSKFRAVEEEDLKVFNEAVGMLEGVGYEPLIVSTQVV
                     AGTNFKFICNATSVTNPPQNYLAEIVVFKPLPCDEHNATITSINIIK"
     gene            complement(16455..16634)
                     /locus_tag="OE968_002719"
     CDS             complement(16455..16634)
                     /locus_tag="OE968_002719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219989.1"
                     /translation="MGKDRFEKVYSQGKINATEIWVDKETGVNYVFHYYGHAAGFTPL
                     LDREGKPVISPIVSK"
     gene            complement(16919..18394)
                     /locus_tag="OE968_002720"
     CDS             complement(16919..18394)
                     /locus_tag="OE968_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCP7219990.1"
                     /translation="MKRKPQYLIIFEHIIQQIYTGKITIGDRLDSIKSMSEEYMVSKN
                     TIKTVIKMLSEKGFIETKAGSRPVLIQSTSKQSIESDLLYEKILQISEIYKIFSLIFP
                     SIAMYNIKRFTSKDFEELNEIIDCMEKNSSNYLVFKEQRLKYINKLISKTNNFLIHHF
                     CEIIQHDVIISQLAYNFDNLDNLDNCCIDFFRNKYIEQVRKTYLYGLDGNLIEFKKLL
                     TYMYKACRESILKMVENRAPQSIDTSSFNSVTLEKCYLYDLIVSDVICQIFEGNIKIG
                     DCLPSITSIINRYNVSLPTVRSAYNELNELGIAKTINGKGTYITLFSEYDDDYINTEE
                     GAKRLSLLLDAMEFVTITLEDVVLLLGNKMDLIAVDKIETHLRYLQNNCEECKVYPDF
                     VLLCKIVDYTQIYVLQETFLHLKQYMIFGIYLERFFHEEYNEILKTRFDVCFEILRYL
                     KKGDVERFAESFSNIFKESLQYLKKVISSLNVDMRVKLDIL"
BASE COUNT         6211 a         3270 c         2062 g         7165 t
ORIGIN      
        1 ttctatatca gagccaaagg gaatccatgc attaccaaac tctttatctt taaataaata
       61 agctaatcca gttatttgct tcaatctaag aatttcatca acttccatac ccaggtgctt
      121 tgatatccat tcatcagatt ttccaatttc acaaagttca gttataattt tactcattaa
      181 atccacatta tgagaacctc ttgcacgatt gtgtcgaata gtacttgcca ttctttcatc
      241 aagagattta tcaattactg aaacaggaag aagtccattt tctctatcat atatatcctc
      301 attttcaagc attactctat atctatgaaa accatctaca ataatatact tatccttttc
      361 ctcattataa taacagacaa ttggcattgt atacccatct tcttttatac ttttatacaa
      421 caactgcatt tctggtgggg ctactgcatt tggattatag tcgttagatt ctatcttttc
      481 gattggcact gcgatgattc catatacagg acttttatat tccatagcat cttaactcct
      541 atctaatgaa ttttttcata tttcttctta atatattccg ttctaattct ctgttctttt
      601 gtaggaccaa atcccataaa tctacacata tggtcatttt ttaaaataca ataacacatt
      661 cttttccaac ttggtatatc tttggtaaat ttaatatcat ccgtatcatc aggtatatca
      721 tccaaaaata tgactctact ctttttatct tttgtatgat ttgaaactcc atttaattct
      781 attttataac cttttctcaa caattcacgt ataactattt ctgacaaacc accacctgta
      841 ttctgccaaa actcaataga tgttgaaaat tttttaatat agctattcct tatattttca
      901 ggtaaggtat caagcaaaaa atatgtgaaa cttttccatg tgtgtccata tggcaattta
      961 acactacgat atcccatagc ttttgttttg ccataaatag aagtaaaatt aactccttgt
     1021 actctagcaa ccaatttcac ccatacatct gggtccaata ttctgtataa atttaaactc
     1081 tcttttgctg aatcattaaa aggtgatgcc actctcattt ttcttggagc tactccagct
     1141 ttatagaata agtcataaat tttattatag tcatagtcaa atttatagtg tgctaaccat
     1201 atatcttcta tttcccaatc atatatagga gatgccgtcc agacattttt aaattcctta
     1261 gttatccagc actttccttt atatccatgc tgtttattca caatagaaca ataacgttgt
     1321 agagattctg ctgctcgtgt tcctaataag caaacaactt ttgcaccttc atgtatatct
     1381 ctaatccatc taccaaattg ttttgccaaa ctttcttgtc tcattttata tttataataa
     1441 gtaaaaggat tatttttttg atttattatg tattctttga ctggcatttc ccttacccat
     1501 aactcttctt tctcatcatc ccatggatac caatacattt cataatttcc tacagcagtt
     1561 cttgtagcca ttggtaaaca cacccaatat ggttcaatat cttcaatatt atcttcaaat
     1621 actttttcaa catattcagt agtcaaacta tattgagcct caaaatcttg atgaaatact
     1681 cctattttgg aacttatatt attctttctc ttataatcca aaactaaatt tagcagtaaa
     1741 ccactatctt ttcctccgct aaaagataca tagatataat caaattcatt aaaaagataa
     1801 gaaagtcttt cttgaaaagc ttcaaataca tcggattcta aatatctctt atccatttga
     1861 attatcccct ttcaattaga agtttataaa accttacaat gcaatattat tatgcttttt
     1921 tagcagtaat cagcataaat tatacattat ttaaatacac aaatccaact aactacatat
     1981 aattataatg taattatact tttgtattat aaactatatt ttatcattat tttacatttt
     2041 tttccaatat atataaatat catatttttc tattagctaa aactaattac tttatatttc
     2101 tacgtattag tataataata cataaaaact tgaataatgc ataaaaactt gacatactgt
     2161 tgtcataatt actttgctat aattaaaagt aaaaatggag gtaaattcta atgtatgaac
     2221 gtatgcttga taaaagcaat aaaccctgtt tgtctcaaat aatagaatat ataggtaaag
     2281 atggatatgc acgattgtgt aagttggaaa cttacttgaa aactcaatat aatttatcaa
     2341 gagaacttcg atttcctttt ggaaacaatt atggttgggg ttacaaatat agccataaat
     2401 cttttcattt attttatgct ttttttgaaa aaggtgcatt tactgttctg attcagatag
     2461 gtgacaagca agttccagca gtagaaaaaa cgttggtagc tttgacacca aaagctaaag
     2521 agctctgggt cactcgttat ccttgtggca ataatggagg ctggattaag tatcgtattt
     2581 tagaagatgc agacttactt gatattattc aatatataag agcaaaaaaa tctccaccta
     2641 aacaaaatta acttttattt tttgtgattt aaatatagtg tatataaatt ccattctttc
     2701 catataaaaa aaataatata aaaaatatct attagtataa cttatttagt atgtcttatt
     2761 ctacttttta cagataatta aaaagtttta tcataaataa atcataacta gacatcctag
     2821 taaatcaaaa ttaatttatt cttttttatt agaatttttg ataacagtcc ctatacatat
     2881 gccaattatc attccaaaaa ttagaccata acacattgtg atacctacat ttcctttaga
     2941 aatacctata gcacaaccta tagccattcc aagtatcatg cctataaaca tacatataat
     3001 aactaaattg ttgtttttat tcatagtttt ctccattcaa tatattttaa attgcctagc
     3061 tcgccttctt agcttaaaac aaagaaatat aaattaactt tctttcattc taatatctgc
     3121 ttgtataaat gtcaaacaac acatttcttg tcataacctc ctctttttga agtaagtaca
     3181 atctcccaga cgcaataata tcaatttcct aaaaccattt aagtaacttt tatatttaca
     3241 taatatttac aatcataaac tatattttta ttcatttata catcataaac actccctact
     3301 aatcattatt atacttaaaa taatgttcat ttataataat atatctaaca cactttaatt
     3361 gaaaaaaata aaactttgcc tttcattccc atatataaat aagtatactt tttgatgctc
     3421 tattacaaat caactaaatt aattgatata aattatcatt ttctgttgaa aataccattc
     3481 gcacatgcta tacttaattg cataaatggt aataaatgtc atatgatttt acaaatctat
     3541 taataacaat tattactttt actgtatttt aaattttttg gactaaatat caagaacttt
     3601 ctaaaataca aagtacaaaa aatttatata agttataaat ttatatgaac tagataagct
     3661 caaacaatat gttatgtata aactgtgtag tattcggtta taaatttata taaattatat
     3721 aagctagata aagtattacc tcaactatat aagctagata tataaattgc atatataagc
     3781 tatataagaa ttatttcaac tatataaact acatatgtaa attatataca taagctagat
     3841 atataaacta gatatataaa ctagatatat aaactgcata tataagctat ataagaatta
     3901 tttcaactat ataaactaca tatgtaaaat tcatgtaaat ttactaatat aaatcaaata
     3961 aaattactaa actctctaaa ctaattttgt aaaacatact ctatttttaa catttgttac
     4021 cttatacata agtacaaaca aaatctaact aaatgaaagg ataatgtaaa atgaatattt
     4081 taaaaatgaa aaaaacaggg atatttttag gaggagtact ttttggtact gtaggtgtta
     4141 agatactttc aagtgattgt gttaaaaaaa cttgcactcg tgcaacagca ggagcattga
     4201 aagttaaaga ttctgttctt gaaacaacta cgaaaattca agaaaatgta gaagatattt
     4261 tagctgaagc aaaagaaatc aacgagcaag aagacttatc tacatctaag gtaaacgttg
     4321 tacaagatac tcttaaatgc gaacaagaag ttcttaaaac tgaaactata aaaactgtag
     4381 aagatactaa ttctaatagc attaaatgtg aagaaatcaa agataacgta attgaagaaa
     4441 aaaatagtac ttgtacaaca gaatagattt aatgattatt atgattaata atatcaggag
     4501 gaagtaaatt gaatttttat ataaaacacg aaataagagg tcgtatacgc tttgacttac
     4561 aacttggcaa attaaacaac aagcagtccg atactctctt atattattta acttctataa
     4621 atggtattac caaagcaaaa gtttacgata gaactggtga tgcagtcatt tattacaatg
     4681 gtgaaagaga atacataata agagaaatca ctaaattcag ttttaacaat agcaaaatag
     4741 aaaacctagt tcctgaacat accagcaggg aattaaacaa ttattataga gacaaattag
     4801 caaataaact gctagtcaaa agtatctcca aaatattttt tccaaagtcc ttaagatttt
     4861 ttttaattgg acttcattct ataaaatatt ttaaaaaagg tctctcttcc ctgctaaata
     4921 aaaaaataga agtttctgtt ttagatgcca ctgctatagg tatttctatt tttagaaaag
     4981 atatcaatac ggctggttca gttatgtttc ttcttggtat cggtgaacta ttagaagaat
     5041 ggactagaaa aaaatctata gacgacttgg ctcaaagtat gtcactaaac attgaaaaag
     5101 tatggttaag aaaaggtgac actgaaatcc taattccaat ttcagagata aaggaaggag
     5161 atttagtaag tgtaactatg ggaaatatga ttccattgga tggagttata gtatcaggag
     5221 aagcaatggt caatcaggca tcacttacag gtgaatccct tgcagttaac aaaaaagaag
     5281 gatcttacat atatgctgga actgtaatag agcaaggcaa tattgttatg tgcgtcaagg
     5341 aaaaagctgg tactactaga ttccagaaaa tagtaactat gattgaggaa tctgaaaaac
     5401 taaaatcttc tgtagagagt aaatttgaac atctagcaga tacattagtt ccatacagct
     5461 ttttaggaag tatattaacc tatgcaatta ctagaaaccc tataaaatca ctctctatat
     5521 taatggtaga tttctcttgt gcattaaaac tctctatccc tatttcagta ctatcagcca
     5581 tgagagaatg taacaataac aacattactg taaaaggtgg aaaatttctt gaaggtgttg
     5641 catgtgcaga tactattgta tttgataaga caggcacatt aacaaaagct caaccaactg
     5701 tttcagatat aattacattc caaaattata ataaggagga tatgttaaga cttgcagctt
     5761 gcttagaaga acacttccca cactccatag caaatgcagt agtttatgaa gctgaaaaac
     5821 aagggcttag tcacaaagaa atgcatacag aagtagaata tattattgct catggcattt
     5881 caacaaaagt tgatgataaa aaggttgtaa taggtagcaa acattttgta tttgaagatg
     5941 agaagtgtac tatcccagac ggtgaggagg ataagtacaa taatctatca gatgagtatt
     6001 cacacctatt tatggcaata tcaggtaaat tatcagcagt tatttgcata aatgaccctt
     6061 tacgaaaaga agcaaaatat gtaatttcaa atttaagaga atgcggaata aaaaagattg
     6121 tgatgatgac tggagatagc gaaaaaacag ctaaatctat agcaagtaaa gttggtgttg
     6181 atgaatatta ttcagaagtc ttaccagaag acaaagccaa ttttgttaaa agtgaaaaac
     6241 tcaaaggtcg caaagtaatt atgattggtg atggaatcaa tgattctcct gctatttcag
     6301 aatcagatgt cggaattgca atgagtgaag gtgctgaaat agcaagagag atttcagata
     6361 ttaccatatc agcagataat ttgaataatt taatcgtttt aaagcagatt agtaataagc
     6421 ttatgaaaag agttgattta agttctaagt ttattatcgg ctttaattta ggtttgattt
     6481 tacttggtgt aggtggattt gttagaccaa gtacatctgc ctttttacac aacgcatcta
     6541 ctgtcggaat aagtttaaac agtatgacaa atttattgga aaacaccaat acttataact
     6601 accattaatc tccattacat aaaacatatg atataaaaaa tttataattc atctttttaa
     6661 aaaaatatgt cttaaaatta gcttttttct aatcaaaatt atataaagca tactttacaa
     6721 attttaaact caacttattt ctatttttta caaaaaagga gatgattcaa attttcattt
     6781 tgaaacatcc ccttttgtaa atttctttaa aatttatata ttaattatat tttcaaccaa
     6841 taattgtatt ttcaaccaat ctttcttcat agcattttaa atcattttgc tttagataat
     6901 taaattcaga ctctacataa ataccacagc ctaccaattc aattgtcaaa ttaggtatat
     6961 tttcctttag tatactagtc tgctcataaa taattctttc caataaatca acttgtaata
     7021 tagaaaaatg cttcataatc tccccatcac tatctatatc tttcttgatt tcataccaac
     7081 tctttgacaa aattccctta aaatcaatat accctagact cttcaatata tctatactat
     7141 cgctccatgc atacttacta ggtttatcaa agtatgactc tagtttcttc ttctgctcat
     7201 ttgtaagtga atcataagaa agcttcttat taaaatgtgc cttcaaagaa atcttagcca
     7261 tagaatatgg acttctacca gagtttaatc ctgcattttt gaacttttca attcctttat
     7321 cttctactga agaccatatt gagtttattg aatctgaatc attgtattta acatcaagac
     7381 catgtgtaat atttatatag ttttgtggaa atacatattg ataatagaca tcttttttat
     7441 catcatatag agagaagtat ccactatcat ataaatgaat atgcaccttt acttttaaac
     7501 tatcctctaa aatatttcgt ctaaggttcg ggatatttgc atacatggtt acatatttta
     7561 tggcatcaaa gtttttattt aatggaactt caaaactaat ttcatctcct gtcaaaagct
     7621 ttttcacttc ttcttcatta caatcatata gagaatatgt attttcaaat cccacacgtg
     7681 atttcccatc taaactgcct gttaatgcta ccttcaaaat atggttatct gttttttgcc
     7741 attggtaagc atcttggtca agaaactctc taatctgtct attttgctct ttcgcctgat
     7801 ttataacctc gttttcatct tctgtaatcc ctacatggca tctatttaag atatttacta
     7861 tattgcttcc aaatgggaat gtccatagtt gaaaagctgc tgcctcaacc tgacacaagt
     7921 atctaacctg atttaattca atttgatgga taagtttttt ctgatattca ttcatctgat
     7981 taccactatc tgacatttga taaatcaatt ctcccattgc aagattatct tttttcttat
     8041 caatcttatc agtaatgata atttgagttt ccatcatatc ctgtactttt ttaaatatta
     8101 tagaaatctc ctctgaattt tccattttta agcttccaaa ctttgtgctt aattcagtta
     8161 aaacttcctt catctttaat ttacttatct cattttcaaa aatatcttga tttttaactg
     8221 tactatcgaa tttttctaca aatggtataa cagattcttt caaagtttta tctttaaatt
     8281 ccaccatttg agtattcaat tcatctaatt tcttaatatt attttcttta tctttaattg
     8341 cctctttaac tacctctatt ttactctcaa aactagattt tacattaaga caattattaa
     8401 caccactaat cgcagtattt ataagagaac aagcagaact tccaatactc aatgcatttt
     8461 taattttaga tgtcttttgc tgtctttcaa tagcttgttt acttttctct agtgcagcta
     8521 acttatcttt ttgctgttta ttattgtaat ttgcctccaa catacctatt tcttttttct
     8581 ggatttttgt gtaaatttcc ttatactcgc tttcacttaa cccctctttt gctctttgaa
     8641 tatcgtcagc tttgtctgca taattatcat catctataga cttaactata atctccttaa
     8701 tttggtcaaa tttagttctt ctttcttcat caacacctgc caaattataa gtcattttat
     8761 ctaaagcatt ttttctatct tcacttagct gttctccaag tacaaatctc ataccatcag
     8821 aatccaattt aaaatctgaa aaattaacca tcctgttagt ccatttgtat tcctcttctt
     8881 tagctgaaag attttccttc aaagattttg cactgtcaaa tgcccctaga caagcttgac
     8941 caacaccact aaatgcagtc agtaaactca atgcgctttg tattccagaa agaattaact
     9001 gtgttttcat ttgttcctca agttttgcct gtttcttttt tagttcctct atgtcttctt
     9061 gttcatcttc tttcatcttt ataatttctt gaatcaacag gttcattttt gcattaacag
     9121 aaagcatttt attctcaagt tcatttttta aaacctctat ttgttgattt ccagattcaa
     9181 tttgagttag gatactttcc ttatatgtat tgaaatatcc ttcttttaac tcatctttct
     9241 tcccttgttc caattctctt aaggtcttat ccagataatc tgtcaaagaa cgaatatctg
     9301 taacacgatt tcctccaatt tcactttctt caatcatctg cacataaaat gctgtcttct
     9361 gctcaagtgc aaataaaatc atactccatt cgctaaaatt ctgatttttt cctacaaaag
     9421 attctattct atcagactgc atcaatttat ttataaggta ttcatagatt tcctttgctt
     9481 ctttataaaa ttctttcttt gtattcatat catccagaga aagtactgct ttatttttct
     9541 tctcaaaact atagtacttc tgaagtattt ctctatttaa ttgcatctct attttctcaa
     9601 ctgcatgaaa aatttcataa atatgtgaaa gttctaaaat atcagcttct aaaattccta
     9661 ctgcacacaa cagtctaaga tttctataac ctttaattcc agaaaaacca aatctctcga
     9721 aaaattcata gaagaatgta tctattgaca aagaatactc ctgctttaac aattcctttt
     9781 cttttagtgc atctccagag tgaccggctg ttccctctgc tccggctgaa cctgaatctt
     9841 cacgtttgct aattatccag tccttatgtt cttcataaag agcatttaat ttctctccat
     9901 catctgctgc ttgcttctga tttaaagcat gattaaacac atatctatca aaataatagt
     9961 agtttctatc actattatcc attggaggag aggtacctat atatcttatt gtttcttcat
    10021 atatacctct aattccacca agacctcctg caccaccagc tcctccagag cctccttttc
    10081 ctgctaaacc atgatttcca tcttttttac ttatagcact ttttaataaa ggagcttttc
    10141 caaggagata aacctgtcca gacttgcttc caagacctgc atttccacca ttacctcctg
    10201 tgcctccagt tccaccttgt tttccttttt ctgcttttac cacatagtat tttgtacctt
    10261 taacattagc aaattctttt gactcttttt tagaacctat tttagcattt gccccagctt
    10321 ctccagttat ccctgtatct cctttttttc catcttgtcc atttccacca cgtccaccat
    10381 ctacgtaaag tttaagttct cctctttttt ctatttcttt aaaagataat atgatatcac
    10441 ctgaagtacc tgcattattg ccatttcttc cattcattcc gtcgtaaata gaactttctc
    10501 caaccaattt ttctgcatcc ttaccagata cgttgattga ataagtccct tctggtatat
    10561 gtaatttttc tgtaagtagt acaatattct tacctgagaa gacttctttc tccatattac
    10621 agtcaatttt caactcacaa tctccataca tatatataga tgacaaaata ttaagttgat
    10681 aaccagatat tattttagtc aaatccgata aattcacttt aggtatagga atatatatag
    10741 aaagtacatt ttctttctca tatgatttta tatatgtaca actttgaatc ttctctatcc
    10801 tatactctgc atcttcaagc tttttggctt cttcttccct atattcttct tctgctatcc
    10861 aatatttgat atcttttaat gtatcttcta aagtattttt tagcaatgat tttaacaact
    10921 cacttagacc aacaatatga gtctcactac agtaactatt taactctaaa agaagacgtg
    10981 tttcttctaa tatattcact ttctgtacgc catcaccata tgaaagttct tgtacaaact
    11041 ccataatctc tttcatatta ttagtcctac tacataaatc tgtatacatc ttatctaatt
    11101 gaatcttttt atcttttaga ctatttatag aagatagaat ggaaatagaa tcttccatac
    11161 cttttttaac actttctata taaggaacta aaagtttttc taggtcttta taggttacat
    11221 caacagcttt ttgtatttct attttacaag aagcagtaag catcaacccc aaatctgttt
    11281 tttcaaatgt ttcaggtaga tttttcattt catccaacaa cttttctggc tgtttatcta
    11341 gtggattaca taatttaata gatacaccat ctgataatgc tacatttaat aagtacacta
    11401 attccttaca accgtcgtaa tctttctctt gactatctag gtcttctttt gctttttcca
    11461 atatatttct tattttttct tctgttacat taccaattag tgttttaggt attttattga
    11521 taagaaagaa gaaattttct ttatactttg cataatcacc aagcatatct ttcaaatttt
    11581 tgcctgtttc tatcaataat gtatgtctag agtccagtag ggattgatag tctaaaataa
    11641 ctaccatccc ttttaccttt gaagatgtgg aaatagtttc ccttacaagc atagcaccag
    11701 caatcatata ctctgctcca cggttatcaa aaaaacctgg gcaatcacat aatgaaaaat
    11761 ctctatttgc aatatctaca acttctggac ataaagtctt agaatataca ccatttccaa
    11821 tttcgacagc tgaatctttt gcagttatat atatttgtcc agtctcttca tccgtttttt
    11881 cttccatcac acagcctttt aaataattta tacaagtact ctttccaacg cctgaagcac
    11941 ctaagaataa caaaattgac ttttctttta agtcatattt tctaagctcg tctcttcctt
    12001 cttccaaaag gtttacgatt tcactataaa gtttatttgc catacatcca tccctttcta
    12061 tatttcggaa caatagcctt gatatttttc tttaataaga ttctcttcta cctttgaaac
    12121 agctgttgat aacttagtgt ttggagcatt aaatcctcca ttgtctcctc tatctccata
    12181 ttcagcgtat tctcttgctg gtcctgtttt accttcattc cagcttccac cactaaattc
    12241 tatatgatat ttaattatac tatctaactt ataatcccaa cttgtaaaat atcctgtata
    12301 gtatacagtc ttatctatac cacttggaga aaatgaaagt gtattatatc cgtgatagcc
    12361 accacttcct ccatatccac ctaaacctgg tctaccattt ggacctgctt ctccatcttt
    12421 cactgttata tcacaatgat taattattct atttttttgt tcctctgaat ctgaaatgaa
    12481 gtaaatatta cctttcttac cagcatttcc acctcttcca gcatttccac cagctccacc
    12541 tttttcacct tttttgccac ttgtaccttt ttcaaaatac cctttaaaca tctgtccgtg
    12601 gaaataactt gtatatcctg catcagctcc attacttcca gaagctcctg tttcaccatt
    12661 ttccccatct attcctttag aaccatttcc tccatttgca atcagtgtta gacgataatt
    12721 tctaatttct tctttaatat ataagtaaat attacctgca tctctaccat cttcaccatt
    12781 tttcccatac atagaattat ctacaagttc tccgctcttt ccacttacat taatttttac
    12841 attactacct acatcaagat tgttagaagc aagaataata tttttctctg atgcaaagtt
    12901 cattccaagg ttatcatcca tataaatagt atctttagca aagaacataa atgtagaaac
    12961 attgtcatct acttttctat ttttgaaata ttccaataca ctgctaatta ctaagtttgg
    13021 aattaatgct cttatttcaa tacctttctt atcattaata ttaattgttt ttactataaa
    13081 tggatttaaa atgtatttac caataaattc tctaattatc tcattacctt cttctccata
    13141 tgcacttaat cttgttatac tgtcttctaa ctcttcattt tgtgtaactg taacatttgt
    13201 caaaattgaa ttaaaatcac ttacactata tacataatcc tttttatttg caacttccat
    13261 taatttttct ctatttggta atgtaaatac ctgtttttgc acttcataag aaactaaaac
    13321 tttttctaaa ttctttctta ttataatgaa gttttgttcc attatcttct tacttgcctt
    13381 ttctataata aattccatat gtacagaagg taataaaatt tccccagttc catgttctgt
    13441 atatttactt aaagcatcaa ttatatctaa gtttcctttt atcttatttt gtaatttcat
    13501 gcaactatct tgtaagaata atccactttg tttggctaat acgttgataa atctctctat
    13561 agtaagactt gttgtacttt ccaaccagtt tttaaatact tttacaacct catcatattt
    13621 tgctatttct tgaatcattg ttatacttcc aataatattg ataaaatctt ctgtatacgc
    13681 cttaacataa tcttctaggc tagatacgat attgttttga atttctttta tcaacgtatc
    13741 taaaactaat cttgcatctg cactaattgg atattggaat gctgatgtct tatctttaac
    13801 ttcatctaat tctagtactt gctttaataa gccttccctc tcatctgatg caagtggctt
    13861 acaaagatga atattttttc cattatcttt tagcaattct tcaaataacc aagctttttc
    13921 ctctatatta ctgtctaaat tttcgcataa ttgttcatat tttcttttta taacattata
    13981 tatttgtttt tctgttcttc ctaagaaact ttttgaaatg aaaaaagtta tactaccctt
    14041 aaaattttct ttatgaagac acatatttaa ctgttggaac aggtctagta cttttgtaag
    14101 tctagaatct aatatatctg cttctggtat caatacaatt actgcacata tagatgcaga
    14161 atttttaaat acttcaccta atgaaactgc tgcactaata tcatgggcta ctcccctatt
    14221 gtcgctaaaa cctgcagtat cacataattt tgcatccatt ccttctattg gttttctcat
    14281 atttacaatg ttcgggtata aagtttgaga aacagctcct gaaccaatct ctgccacagg
    14341 gtctaagcaa tcaatatatg atataccagt atcttcatct tctacttcca tcattacaca
    14401 tcctgcaaga tagttaattg cagtactttt gccacatcct gtcccaccaa gaattagaat
    14461 taaattttga ttttcagcct tatttattgc tacttttcct tcatttaata agagtgttat
    14521 ttcttctaaa agttgattgt tattttctgg catttatttt cccccttggt tatatatttt
    14581 atttaaataa agtttaatcc cttaagtaga ttgcaaagtt tttatactat atttaaattt
    14641 gttttttatt ttttattttt aataaatttg cattttcact aaatttgtat tttcactcaa
    14701 taattattct tctttgttta ttaaaataac tgtgttgtat aatataatct ttatcaacac
    14761 agttatttta tttaatgcgc ttattttatt gtattttatg taatacagtt gttttttata
    14821 ttatatgtcc attattttcc tgtggttatt acatatagat ttttaattat atttgtacca
    14881 ttaatttaaa cattcctata ctactgctta agttttacac ctataccagc ttgaatattt
    14941 tatttttatt tgcttaaata gttcaactat actggtttaa ataggttatc tttatttgct
    15001 taaatagttc aactatactg gtttaaatag gttatcttta tttgcttaaa tagttcaact
    15061 atactggttt aaataggtta tctttatttg cttaaataag ttcaactata ctggtttaaa
    15121 taggttatct ttatttgctt aaattagttc aactatactg gtttaaatag ttttccttta
    15181 gtttaaataa ttcacctata cctacttgaa tagttcactt ttatttgctt aaattctata
    15241 ccaatactgg cttaaacatt atactaccat gattgtattg tctatcttca actacaataa
    15301 aaacaggttc taaatcttta gtagatgtta tttttaattc taaaaaaaca ttatcagttg
    15361 gtaatatttt tacatcataa ttatttaaat tattattcgt gatactatta aatacatcac
    15421 cttgacgttc aaaaaaaaca ttatcaacta ttacaaaata aacatcttct tttctactat
    15481 tttcaacctc tatagtattt tgtttagtta catttagtct catcttccac ctcctattaa
    15541 tattacttaa ttatattaat acttgtaatt gttgcattat gttcatcaca aggaagaggt
    15601 ttaaaaacaa ctatctctgc taaataattc tgtggaggat ttgtaactga agtagcatta
    15661 caaataaatt taaaatttgt tcctgctaca acttgagtag aaacaataag tggttcataa
    15721 ccaacccctt ctaacattcc tacagcttca ttaaatactt ttaaatcttc ttcttcgaca
    15781 gctctgaatt ttgaccatcc accaacaaaa agactcatat aaaaacctcc tttatatata
    15841 tatttattta tatatatagt agtaccaatt ttctcaatat tcaatatttt ctgtgtaact
    15901 ggtcaatgaa aatgcataac tggataaaaa tacttataaa ataacttaac tttacatata
    15961 aatagcttaa tttacatgta ataagattat tctacaatat gaaatacatc ttattttgaa
    16021 tatattctaa atacaataat ggatattttc aattattata cttagaaaat atccattact
    16081 taatttgttt tatttaaaat cacatagaga ctttattatt ttttttattg catgaatagc
    16141 tatttcaggt atcataaggt gatatacccc ctccttgaaa ccacaaaaaa cataacaaac
    16201 tttacgaatc ttgtcttaaa agaccacagg tacattcctt atttgtggat tggagtagcc
    16261 ataacaagca aattttacaa tttttatgat gacaaaaatc aataaaatcg cttagtatat
    16321 aacacgaaat actacttgtt gctattaaga atagttagat aggaagtatg cattatacca
    16381 ataaaggaat caataaagaa agttaaaaca tccctacaaa ttaaaaatct gttacatttt
    16441 tctatattta aacgttattt acttacaatt ggagaaataa caggttttcc ttctcggtca
    16501 agtaaaggcg taaatccggc tgcatggcca taatagtgga atacatagtt cacacctgtt
    16561 tctttatcca cccaaatctc cgttgcattt atttttcctt gtgaatatac tttttcaaat
    16621 ctatcttttc ccattttata atcctccata tttttgattg gtctatgcct tcttcactta
    16681 agtagaaaaa atacataact tattttttta attctaatat gagcacgtaa aaatgtcaaa
    16741 cagcttattt aatttcataa cttcatgtta ctgttcgtaa ccttgtctgt ttacttacac
    16801 tgcattacag caccatttta tcctttacat tattgtattg cacacagtaa aaatgcttac
    16861 tttattggat ttttcaacta aaaaaaggat tttttctcca cagaacattt actatttttt
    16921 ataatatatc taattttact ctcatatcaa catttaatga agatataacc tttttcaaat
    16981 attgtaaaga ctccttaaaa atattagaaa aagattctgc aaatctctca acatctcctt
    17041 tttttaaata cctaagtatc tcaaaacata catcaaaacg tgttttcaaa atttcattat
    17101 attcttcatg aaaaaatctc tctaaataga ttccaaatat catatattgt tttaaatgta
    17161 aaaatgtttc ctgtaataca taaatttgtg tataatctac tatcttacaa agtaaaacaa
    17221 aatctggata aaccttacac tcttcacaat tattttgtaa gtaccttaaa tgagtttcta
    17281 ttttatctac agctatcaaa tccattttat ttcctagtaa aagtactaca tcctcaagag
    17341 taatcgtaac aaactccata gcatccaaaa gcaaactcaa ccttttagct ccttcttctg
    17401 tatttatata atcatcatca tattcagaaa aaagtgttat atatgttccc ttgccattaa
    17461 ttgttttagc aattcccaat tcatttagct cattataggc acttctaact gttggaagag
    17521 atacattata tctattaatt atcgaagtaa ttgatggtag acaatctcct attttaatat
    17581 tgccttcaaa aatttgacaa attacatctg aaacaattaa gtcatataaa taacattttt
    17641 ccaacgttac agaattaaaa ctacttgtat ctatactttg tggagcacga ttttctacca
    17701 ttttaagtat ggattctcta caagctttat acatatatgt taatagtttt ttaaattcaa
    17761 ttagattccc gtccaatcca tataagtaag tttttcttac ctgctctatg tatttattac
    17821 gaaaaaagtc tatacaacaa ttatccaagt tatccaagtt atcgaaatta taggccaatt
    17881 gtgaaataat gacatcatgc tgaataatct cacaaaaatg gtgaatcagg aaattatttg
    17941 ttttacttat tagtttattt atatatttta gcctttgttc tttaaagact aaataattag
    18001 aactattttt ttccatacaa tcgataatct cgtttaattc ttcaaagtct ttagatgtaa
    18061 atcttttaat attgtacata gcaatagaag gaaatattaa actaaaaatc ttatatattt
    18121 ctgatatttg taaaatcttc tcatataata agtcagattc tattgattgt ttactcgtac
    18181 tctggattaa aactggtcta gaaccagctt ttgtctctat aaagcccttt tctgagagca
    18241 tttttattac agtttttata gtattttttg ataccatata ttcttctgac atgcttttta
    18301 tagaatcaag cctatctcca atagtaattt taccagtata aatttgttga attatatgct
    18361 caaaaataat taaatattgt ggttttctct tcatattttt cctcttcgat aaattagatt
    18421 tattgttttt tgtaaggtat atttactttt atttaatagg gcaaaatagt tgcttatttt
    18481 ttcctcataa tctataatta atatagacca tttatatata tggtctaagt tttataatac
    18541 tgtaatgcag taaaatagca tattgtagct atactacagc aaattaacat accattgtag
    18601 tatattaatt ggaataattt taagtacttc aaaattccag caaaacatat atgtgttttt
    18661 gatattatgt atattcgtta atagaatagc tatacttgtt ttacataa
//
LOCUS       DAJMZY010000083        18349 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.083, whole genome shotgun sequence.
ACCESSION   DAJMZY010000083 DAJMZY010000000
VERSION     DAJMZY010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18349)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18349)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18349
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.083"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            <1..209
                     /locus_tag="OE968_002721"
     CDS             <1..209
                     /locus_tag="OE968_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF1540 domain-containing protein"
                     /protein_id="HCP7219991.1"
                     /translation="SSFLDESIYSNLSSNVNNRNCEELVCTVKNCKYNKDGSLCTLDN
                     ILVAPETDRVNLYIETCCSSFECK"
     gene            477..1331
                     /locus_tag="OE968_002722"
     CDS             477..1331
                     /locus_tag="OE968_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219992.1"
                     /translation="MSTFYIQFLYFVIYSFIGWCCETTYCSVLQKQFVNRGFLNGPFC
                     PIYGFGALAIVATLTPFVHTIPLLFLFSIIITSIMEYCTSFILEKIFNMTWWDYSKHK
                     FNIHGRVCLENSLMFGVLSLIVMLIVHPIVVDFINSISKNVLFIFAISIEIYFVLDLV
                     ITVHTILQLNGKLKQINLIIKELKDKKEYYKLITQETIENKLESLVENRLDTLEDRFE
                     ILKEKENYRYAKNRIDELKNKLNTLLSNHKLLHRRIIKAFPNISSNKHTDILNKIKEN
                     IKSIKKDK"
     gene            complement(1517..2953)
                     /locus_tag="OE968_002723"
     CDS             complement(1517..2953)
                     /locus_tag="OE968_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
                     /protein_id="HCP7219993.1"
                     /translation="MREVKPISIDILNTFKQVDEDRLNKLLADELKHLDRKIVVLDDD
                     PTGVQTVHDISVYTDWDKDSMEQGFNEKNSMFFILTNSRGFTVAQTTKAHKEISKNIV
                     DVSKKVNKDFIIISRSDSTMRGHYPLETNLLKSEVERLSEKLFQGEIIMPFFKEGGRF
                     TIDNVHYVKEGEILVPAGMTEFAKDKSFGYKSSDIGEWCEEKTNGKYKSSDMIYISSK
                     ELRELNIEAITEKLKKAEGFNKIIVNATDYVDVKVFTIAFIRAVNSGKEFMFRSAAAI
                     TKILGGVSDKELLTKDELVSKGNTNGGIILVGSHVNKTTQQLEELKNCKYPIEFIEFN
                     QHLVLQENGLKNEVKRVIKVVEEKISRGKTVAVYTRRERFDLDTNDKDKQLMISVEIS
                     DAVTSIIGMLNVRPNFIIAKGGITSSDVGTKALRVKKATVMGQIKPGIPVWMTGKESK
                     FPNMPYIIFPGNVGEISTLRESVEILMG"
     gene            complement(3024..4406)
                     /locus_tag="OE968_002724"
     CDS             complement(3024..4406)
                     /locus_tag="OE968_002724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HCP7219994.1"
                     /translation="MITGYGLLIAFVISIGILLVSIIKFKVNPFLALLITSIITGFMV
                     RMPINEISTTISTGFGNTLGSIGIVIGLGIIFGNILSESRATESIAKGLLAKTGEKNS
                     ALAVTTAGFLISIPVFMDAAFVIMMPIIKYVSRVTKKSLMVFVCALGVGTIVGHALVI
                     PTPGPLAVAANVNANVGSFILYSIIVAFPAALIGGWIYGKRFEKYPAYAIDENDREKN
                     LEQGKDSIKIEDDDSSKVPGFGISMFSLLFPILLILISNVFSMFLEKGSTMSGVLAFI
                     GDKNIAILLGILVAIGFLKKYINKPMGDVVIEAADSAGLILLITGSGGAFGSVINASG
                     IGNFLVDTMSGLSISVVVLGFLLSALLRISQGSATVALVTTSSILGPTILATGMSPVL
                     VGLAICAGGVGFSLPNDSGFWVLSRFSGLSVKDTLNSWTIGGTIAGVVAFIMVLLLSV
                     INGIIPLPGL"
     gene            complement(4542..5447)
                     /gene="garR"
                     /locus_tag="OE968_002725"
     CDS             complement(4542..5447)
                     /gene="garR"
                     /locus_tag="OE968_002725"
                     /EC_number="1.1.1.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxy-3-oxopropionate reductase"
                     /protein_id="HCP7219995.1"
                     /translation="MEGYKMKLGFIGLGIMGKPMAKNLLKDGCNLLVYDINKSAVDEL
                     ISCGAKYASVLEMGQECDIVFTILPNGTIVQDILFGMDGLAKTLKEGSIVVDMSSVTP
                     TESILCANKLKDMGLEFIDSPVSGGEPKAIDGTLAFMAGGKEEIYKKVEPFFNIMGSS
                     SILIGDNGSGSVTKLTNQVIVNLTIAAVSEAFVLAAKAGADPEKVYKAIRGGLAGSTI
                     LDAKIPMIMNRDFKPGGKISINLKDIKNVMQTAHNLDVPLPMTSQLLEIMQTLKVHGH
                     LEDDHSGIAQYFEKLAGVEIKKHNN"
     gene            5843..6514
                     /locus_tag="OE968_002726"
     CDS             5843..6514
                     /locus_tag="OE968_002726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCP7219996.1"
                     /translation="MATFKRLQEQAYDYLKELILSGEMIENEIYSETKLASEIGISRT
                     PIRDALQRLSQDGFIDIIPSKGFRIHQITANEIVEIFQIRSAIEGFCTFLITSQYKEA
                     RAVETISKLKHLLDKQKDILLGDKNLNSFAEYDTLFHTTIVSYAQNTEFDKMFNNYMY
                     RIKKLALDSLSHEGRLETTLKEHTDIFNNIANGCIEDIYRTTLIHMETPKYINLEDFC
                     NNKLF"
     gene            6617..7165
                     /locus_tag="OE968_002727"
     CDS             6617..7165
                     /locus_tag="OE968_002727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219997.1"
                     /translation="MIFLNEDVVTNETIDKDYAIEEVRMACKHFGDLYFYFSKVLFEE
                     FGEDKTSEILRKVLFERSEERAIAMRERAHENGDELIADNIISTTDVPFLGWVPEFEE
                     LHCPYGASWLLRFEENPWFKKFASLYCDVTDTTVAEVFTGDTSHKITKNILWGDKSCE
                     RIYFHDDKVSEGKYTYGNKNCK"
     gene            7427..7735
                     /locus_tag="OE968_002728"
     CDS             7427..7735
                     /locus_tag="OE968_002728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7219998.1"
                     /translation="MFNKIYEKKEFIVFQVKKGYVVYNTRKSFEEGHTHLKHFEAAKT
                     AIDLAINKKIPRSKDGYYLTSLIRISDDGYYIDKLSELLYVREQKGKKEKYCNSGYQM
                     "
     gene            complement(7897..9687)
                     /locus_tag="OE968_002729"
     CDS             complement(7897..9687)
                     /locus_tag="OE968_002729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCP7219999.1"
                     /translation="MKKSKGFKKTIGRLLPFVKKYKFSFIIAIICIISAATMNALAPK
                     TEGLIITQLTKDVISIAKGVPGASVNFDYVTKILVILACIYFANAIFTYTSSFLLTNA
                     IQNTMRDLRNEVENKIRRLPISYFDSNSFGDVLSRISNDVDTISNALQQSFMQIVNSI
                     LVIILALSMMFTINIYMALIALFIIPISYFVSKFVVKKSQSRFSLQQNALGKLNGKVQ
                     EMYTGFNEIKLYGKEEDSIKEFKKVNQELCENGFKAQFISSMMNPMVSLVTYFGIAAV
                     AVVGSIYAVSGGITVGNLQAFVRYIWQINQPLSQMTQLSTVIQSSFAAIERVFEILDE
                     EEEIPDVENPVKIENVKGNVTFEHVNFGYGENSTLIEDLNAEVKSGQMVAIVGPTGAG
                     KTTLINLLMRFYDVKKGAIKIDGVDIRDMKRKDLRSMFGMVLQDTWLFNGTIFENIEY
                     GRFGATKEEIIQAAKVANVHHFITTLPDGYNMFLNEEASNISLGEKQLLTIARAFISD
                     PSILILDEATSSVDTRLELMLQKAMRNLMNGRTSFVIAHRLSTIRNADLILVMNNGSI
                     IEQGNHDELMEKGGFYEKLYNSQFADKESE"
     gene            complement(9687..11414)
                     /locus_tag="OE968_002730"
     CDS             complement(9687..11414)
                     /locus_tag="OE968_002730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003496244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCP7220000.1"
                     /translation="MKLILSYLKNYKLLIVLNILAIFSFALVELGIPTIIAKIIDNGI
                     ANQNIAYIKQMGIVIVIISIIGVVGSILLGYCSAKVSTSVTRDIRNDIFEKSQEFSHT
                     EYNKFGISSMITRTTNDAFQIQQFVNILLRTALLTPVMFIISIIMTIRTSVELSIVLA
                     ISVPFIIIGVAIIAKVSQAISSKQQKGLDKLNLISRENLTGIRVIRAFGNDDYETERF
                     EKTNTYYANVSKKLFKLMSITQPAFFLLLNIAVLAVFWISSEKINIGELQVGQLVAFL
                     EYLFHAMFSIMLFSMVFIMYPRAEVSANRIKELLNEEPLIKNPENGIKDTENKGIIEF
                     DNVTFTYPDGEASVLKDISFTAKTGETVAFIGSTGSGKSTLINLIPRFYDVTEGSIKI
                     NGVDIREYDLKALRKKIGFIPQKSLLFTGSIANNIRFGKHKAGESELEYSAKVAQAYE
                     FISKKPRKFDELISEGGANVSGGQKQRLSIARAIIRRPEIYIFDDSFSALDFKTDAIL
                     RAKLKKETKDAIVLIVAQRISSIIDADKIIVLNEGQVVGMGTHKELLKNCEIYYEIAT
                     SQLKKEELE"
     gene            complement(11659..11925)
                     /locus_tag="OE968_002731"
     CDS             complement(11659..11925)
                     /locus_tag="OE968_002731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase family protein"
                     /protein_id="HCP7220001.1"
                     /translation="MNLEPKKLIEQIGKEKDKKDIWIVGGGDIVKLFMKDNLIDDYYI
                     YILPIILGRGISLFKSGIDKTNLNFKKASNIGELVKLEYSKKQK"
     gene            12223..13335
                     /locus_tag="OE968_002732"
     CDS             12223..13335
                     /locus_tag="OE968_002732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HCP7220002.1"
                     /translation="MKISEVATPNFLLDLDQLEKNIDKIQQICTNNNKQLWPMLKTHK
                     STYIARLQKNAGASGFLVGTLDEGEALIKAGFEDIMLAYPYMGEVNINRIVTMASKIN
                     LICATDNIECAKAYSEAFSKSKIECKLLIIVDCGLHRFGVEPEKVVELATEISKLENI
                     KIVGISSHPGQVYGCSSPEGVPDVCVQEDSSMEKAYKALTDNGFNIEIVASGSTPTVE
                     SEAASKTITAVRPGNYVYYDAIQIGLGCATEDMCALTVVCTVISKNSSGYYLIDCGSK
                     CLGLDKGAHGNSSIVGYGRVCGHPELTIDSLSEEVGKIKVNGETDIKIGDRIRIIPNH
                     SCSTANLTSNLLGFRGDTIEKVIEVDIRENSKQIIL"
     gene            complement(13699..14208)
                     /locus_tag="OE968_002733"
     CDS             complement(13699..14208)
                     /locus_tag="OE968_002733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside recognition protein"
                     /protein_id="HCP7220003.1"
                     /translation="MSQQNTGNAIVNSKPKKTAVEIFMGGAKKGFYIGVEQILPAMIM
                     GYVIVQFLQLTGLVDILGNIFGPVMGIFGLPGESVLVLIAAFFAKAAGAATAANLFAQ
                     GLITAPQATILIMPCMLMGTLVGHYARIVLVANASTKYRMLLLAVPIFDAIVGMLIVR
                     VLLTVMGLM"
     gene            complement(14210..14857)
                     /locus_tag="OE968_002734"
     CDS             complement(14210..14857)
                     /locus_tag="OE968_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220004.1"
                     /translation="MDVTAGDNKVTWKGYLSLFVLIVLFSGVFKDSQGFLKALDFANL
                     TGSFGTIADGVDFMGKGGTGAKDGFLFALTLIPTVCFAVGLIDVVESMGGMKAASKIF
                     NPLLRPLLGIPGIAGIAFVSSFTSSDVASIMTKELFESGEITDDERTIFVAYQYAGSA
                     VILNTINTQAPLLPIALLALGPIILIEIFCKILGANLVRLIIGVRNKKNKAKEAV"
     gene            complement(14871..16043)
                     /locus_tag="OE968_002735"
     CDS             complement(14871..16043)
                     /locus_tag="OE968_002735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HCP7220005.1"
                     /translation="MNTYLNEISKFVDENREEIVSLWKEIVNIESYTHCKESVNKLAK
                     RLKFEFEKEGLDCELVDVGDNGSTLIGTLGSNINKKPIIFSGHMDTVFETGTFGENPF
                     KIIEGKAYGPGVLDMKGGIIISLYVIKALNKIGYKERPIKIVFSGDEEIGHKDSTGAD
                     VILREAKGGLCAFNMETGLVDNSLCVGRKGRIGCNIHVKGVETHAGNDFEGGRNAIEE
                     MANKILRIQKLTNLDVGTTVSVSVIKGGRVENSIPEDCSIKVDLRFEKVEEMENVKEQ
                     VREICKETYIEGTSTEVNFISEMMPFETTEDVMRFHTFVNEVSKENGFGELNAKRLGG
                     SSDASYLTIANVPAICSFGVRGEWNHTSREYAVVDSMFERVKLISTVILNLDKFEV"
     gene            16311..17687
                     /locus_tag="OE968_002736"
     CDS             16311..17687
                     /locus_tag="OE968_002736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220006.1"
                     /translation="MKYKIGFLTTSYFMSDKFKQALKELNDTCEITFIELKGENPFNN
                     LPNIYYEQVDNFDGFVCSGIVPYSELIINIKDIKVPLNFLKLDERDFYKYLFKLLNSQ
                     KDIDFTKSFMDFLREDNNYYDIYSLIDSNKCPYTIKDFNIPQPVYDFKKLNDKLLEIH
                     LDLLRDNKINLSFTRNYIISCELNKLGYDCIYMVPSTESILNTFKSLVNEITLQNLDK
                     NKSATCIVTVNSSEYINEDLIFKNDEIQNQIYNTILNSLSRHGFYGVQVKKNDMKIEI
                     HTTKEMLNNMTNNYTDFFISEDLKEIKYSLNIGWGIGNTNIHAEQNARQANGKSASLN
                     GNCTFIVNDTNDTIGPLYSNKNSNNIEDSSIANKVASFIPLSNTNVSKIMCMINDRNS
                     NNVSAEILSNYMNITLRSANRILSILYKAGIATIVNTKLDNQRGRPKKIYKVDFLSFL
                     NKMQKLNS"
BASE COUNT         6423 a         2982 c         2216 g         6728 t
ORIGIN      
        1 gtagttcatt tttagatgaa tctatttata gtaatttatc tagcaacgtt aataatagaa
       61 attgtgagga attagtttgt actgtaaaaa attgtaaata caacaaagat ggtagcttat
      121 gtacacttga taatatattg gttgctcctg aaactgatag agtaaacctt tatattgaaa
      181 catgttgctc tagtttcgaa tgtaaatagt catagtataa atataagggt gtcaaatgta
      241 attaaactaa catagtgtag agtatctaca actattagtt tgattatact tgacaccctt
      301 atttatttta aataaaattt cattattata accatgttta taatgttcta actgtaatta
      361 aatttgataa atttctataa attggtataa tcaatatgta aattgaattt agtaaattaa
      421 tcataaaaat aaaatatcga gtatatagtg ttatactaac tagaaatgag gtgcttatga
      481 gtacatttta tattcaattt ctttattttg taatttatag ctttatagga tggtgttgtg
      541 aaactacata ttgttcagtt ttacaaaaac aatttgtaaa tagaggtttt ttaaatggtc
      601 cattttgccc tatatatgga tttggagcat tagcaatagt tgctaccttg actccttttg
      661 tacacactat tcctttgttg tttttgttta gtataattat aactagcata atggagtatt
      721 gtacgagctt tattttagaa aaaatattta atatgacttg gtgggattat tctaaacata
      781 aatttaatat tcacggaaga gtttgtctgg aaaactcact tatgtttggt gtattatcat
      841 tgattgtaat gcttatagta catcctattg tggttgactt tattaactct atctctaaaa
      901 atgtgctatt tatatttgct atatctatag aaatttattt tgttttagat ttagttatca
      961 cagtccatac aattttacaa ttaaatggta agttaaaaca aatcaatctt ataattaagg
     1021 aattaaaaga taagaaagaa tactacaaac ttattacaca agaaactata gaaaacaaac
     1081 ttgaatcttt agttgaaaat agactggata ctttggaaga taggtttgaa atacttaaag
     1141 aaaaagaaaa ttatcgctat gctaaaaatc gtattgatga gctaaaaaat aaacttaata
     1201 ctttgctgtc taaccacaaa ttacttcata gacgtataat caaagcattc cccaacataa
     1261 gctctaataa gcatacagat attttaaata aaatcaaaga aaatattaaa tcaattaaaa
     1321 aagataaata ataaaataaa cacataagtt aaataataaa aatactaata cataagatta
     1381 aggtttagaa tattttttgt aaaatactct aaaccctaat taatatacta ttatttttaa
     1441 tcttaattta taattttagt ttattttaat tttaactcag taaatttaag cgtttaaact
     1501 tcaatacact aatatactac cccatcaata tctcaactga ttctctaagt gtgctaatct
     1561 ctcccacatt tccagggaaa attatatatg gcatattagg aaatttgctt tctttgcctg
     1621 tcatccatac tggtatacca ggttttatct gtcccattac tgtagctttt tttactctta
     1681 gtgctttagt accaacatca ctagaagtaa ttccaccctt agctataata aaatttggtc
     1741 ttacattaag cataccaatt atactggtaa ctgcatctga tatttctaca gaaatcataa
     1801 gctgtttatc tttatcattc gtatccaagt caaaacgctc tcgtctagta taaacagcaa
     1861 cagttttacc cctgcttatt ttttcctcta caacttttat aactcttttt acctcatttt
     1921 ttagaccatt ttcttgaaga actaaatgtt gattaaattc tataaattct atcggatatt
     1981 tacaattttt aagttcttct aactgttggg tagtcttatt cacatgtgaa ccaacaagta
     2041 taattcctcc attggtatta ccttttgata ctaattcatc cttagtaagt agttccttgt
     2101 cactcactcc gccaagtatt tttgttatgg cagcagcgct tctaaacata aattccttac
     2161 cactatttac tgctcgtata aacgcaattg taaatacctt tacatctaca taatcggttg
     2221 catttacaat aattttattg aatccttcag cttttttaag tttttctgtt atagcttcaa
     2281 tatttagctc tctaagttct tttgacgaaa tatatatcat atcactagat ttgtactttc
     2341 catttgtctt ttcttcacac cactcaccta tatcagatga tttatatcca aaagatttat
     2401 cttttgcaaa ttcagtcatt cctgctggta caagtatttc tccttcttta acataatgta
     2461 cattatctat agtaaaccta ccaccttctt taaaaaatgg cattattatt tcaccctgaa
     2521 ataacttctc cgataatctc tctacttcgc tttttaataa attagtttca agaggataat
     2581 gtcctctcat agtagaatca ctacgactta tgattataaa atccttatta actttctttg
     2641 atacatccac aatattcttt gaaatttctt tatgtgcttt tgtagtttga gcaacagtaa
     2701 atccccttga attggtaagt ataaaaaaca tactattttt ctcattaaaa ccttgttcca
     2761 tactatcctt atcccaatca gtataaacag aaatatcatg aactgtttgt acacctgttg
     2821 ggtcatcatc taatacaaca atttttctat ctaaatgctt aagctcatct gcaagaagtt
     2881 tatttaatct gtcctcatct acttgtttaa aagtattaag tatatctatg ctaattggtt
     2941 ttacttctct catttaaaac gcccctttat gtaatttgta tagtctaaat gtaatttata
     3001 tgatataaac aatagtttgt tatttataga cctggaagtg gtataattcc atttataaca
     3061 ctaagcaata aaaccattat aaatgctaca actccagcaa tggttcctcc aattgtccaa
     3121 gagtttaaag tatctttaac tgataatcca ctaaatcttg aaagtaccca gaatccagaa
     3181 tcatttggaa gggagaaacc aactcctcca gcacatatag caagccctac taaaactggt
     3241 gacattccag ttgccaaaat tgtaggtcct aaaattgatg atgttgttac taaggctaca
     3301 gtagcagaac cttgagaaat tctaagcaag gcacttaata agaatccaag cactacaact
     3361 gatatactaa gaccagacat agtatcaact aagaagttac ctataccact tgcatttata
     3421 acactgccaa acgcaccacc tgaccctgtt atcaataata ttagccctgc tgaatcagca
     3481 gcttcaataa ctacatctcc cataggttta tttatgtatt tctttaaaaa tcctattgcc
     3541 accaatattc caagaagtat tgctatgttt ttatctccta taaatgcaag tactccactc
     3601 attgtagaac ctttttctaa gaacatacta aatacatttg atataagtat aagaagtatt
     3661 gggaacaata aagaaaacat agaaattcca aaacctggta ctttagaaga atcatcatct
     3721 tcaattttta tgctatcttt tccctgctct aaattttttt ctctatcatt ctcatcaata
     3781 gcataagctg gatatttttc aaaacgtttt ccataaatcc atccacctat aagagctgct
     3841 ggaaaagcaa caattataga ataaagtata aaactaccta catttgcatt tacatttgct
     3901 gcaactgcta aaggtcctgg tgtaggtatt acaagtgcat gacctactat agtcccaact
     3961 cctaaggcac atacaaaaac cattagagat ttcttagtta ctctcgaaac atacttaatt
     4021 ataggcatca ttataacaaa agctgcatcc ataaaaactg gaattgaaat taaaaaacct
     4081 gctgtagtta ctgctaaagc actgtttttt tctccagtct tagctaacaa cccctttgca
     4141 atagattctg ttgctcttga ttctgaaaga atatttccaa atattattcc aagtccaatt
     4201 acaataccta tactacctaa tgtatttcca aatccagtcg atattgtggt tgatatttca
     4261 tttataggca ttctaaccat aaagcctgta attatagatg ttatcagtaa tgccaaaaac
     4321 ggatttactt taaatttaat aatcgataca agtaaaattc ctatagatat aacaaatgct
     4381 atcaaaagtc catatcctgt aatcataatc tttacccctt tatcattcta ctttattatt
     4441 tatcaatttt atttttcttt tactatgata acttaacctc gctgtattta tataatctaa
     4501 tcctaataat atgtatttaa ttatattgat atatttaaat attaattatt gtgttttttt
     4561 atttcaacac ctgccaactt ttcaaaatac tgtgctattc cactatggtc atcttccaaa
     4621 tgtccatgta cttttaatgt ctgcataatt tctaataatt gacttgtcat aggtagtggt
     4681 acatctaaat tgtgtgctgt ttgcattaca ttcttaatat ctttcaaatt aatagatatt
     4741 ttcccacctg gtttaaaatc acgattcata atcattggta tcttcgcatc caatattgta
     4801 ctaccagcta ggcctcctct tattgcctta tatacttttt ctgggtctgc acctgctttt
     4861 gctgcaagta caaatgcctc agaaactgct gctatcgtca aattaacaat tacttggttt
     4921 gtaagttttg taacacttcc actaccatta tctccaatta aaatagatga gcttcccatt
     4981 atattaaaaa atggttctac tttcttataa atttcttcct taccaccagc cataaaagca
     5041 agtgtaccat caatcgcttt tggctcccct ccacttactg gtgagtctat aaattctaag
     5101 cccatatctt ttaatttatt tgcacacaat atggattctg taggagtaac tgaactcata
     5161 tcgactacta tacttccttc ttttaaagtt tttgccaatc catccatccc aaacaatata
     5221 tcctgcacaa tagttccatt tggaaggatt gtaaatacaa tatcacattc ttgacccatt
     5281 tctaaaacac ttgcgtattt tgctccacat gatataagtt catccacagc agatttatta
     5341 atgtcataca ccaaaagatt acatccatct tttaataaat tttttgccat tggctttccc
     5401 attattccta atccaataaa tcccaatttc attttataac cctccatatc ttcacatttt
     5461 tgaaaacgtt ttttatgttt tagagtatac tacataccag tataccggtc aatataaaat
     5521 ataaaagtat ttattttaac aataaatagt aatttttaaa gtcatttatt atatttagtc
     5581 atcctatata agttttaata catactattg ttttcaaata taatatacta cttttacagt
     5641 tttgtatttt aactaatttc aattagtttt aattaatctg cctttaatgt taatcatgct
     5701 tcacacttca ataatttttt atatttttta atcttatctg caatttaaat tgcaaaagat
     5761 tgaccttatt ttcactatgt tgtatgctta aaattatata agtttttgta tttttatatt
     5821 gtttaggggg gtattattaa gtatggctac atttaaaaga ttacaagaac aagcatatga
     5881 ctacttaaaa gaattgatac tatctggaga aatgatagaa aatgaaatat attctgaaac
     5941 aaaacttgct agtgaaatag gtatctctag aacacctata agagatgctc ttcaaagact
     6001 tagtcaagat ggatttatag atataatccc aagcaaagga tttagaatcc atcaaattac
     6061 agcaaatgaa attgtagaga tattccaaat acgctctgca atagaaggat tttgtacttt
     6121 tttaattaca agtcaataca aagaagctag agcagtagaa actataagta aattaaaaca
     6181 tcttttagat aaacaaaaag atattttatt aggtgataaa aatttaaact catttgcaga
     6241 atacgataca ttatttcaca caactatagt ttcatatgct caaaatactg aatttgacaa
     6301 aatgtttaac aattatatgt acagaataaa aaaattagct ctcgattcat tgtcacatga
     6361 aggaaggctt gaaacaacat taaaagagca cacagatatt tttaataata ttgcaaatgg
     6421 atgtattgaa gatatttaca gaactactct cattcatatg gaaactccta aatacattaa
     6481 tttagaagat ttttgtaaca ataagttatt ttagcattat actttcattt attaaaaata
     6541 tatctatctc aaattaattt cctaatttat aaaaaatatt ctataattat attgtaacta
     6601 atacttattc taaggagtga tttttttgaa cgaagatgtt gtaactaatg aaactattga
     6661 caaagattat gctattgaag aagttcgtat ggcatgcaaa cattttggtg atttatattt
     6721 ttatttttcc aaagtgttat ttgaagagtt tggtgaagat aaaactagcg aaatattaag
     6781 aaaagtttta tttgaaaggt ctgaagaaag agctattgct atgagagaga gagctcatga
     6841 aaatggagat gaattaattg cagacaatat tattagcaca actgatgttc catttctagg
     6901 atgggttcct gaatttgaag agttacattg cccctatgga gcttcctggc ttttaagatt
     6961 tgaggaaaat ccttggttta aaaaattcgc ttctctttac tgtgatgtta cagatactac
     7021 tgtagctgaa gtatttacag gagatacgtc ccataaaata acaaaaaaca ttctatgggg
     7081 agataaaagt tgtgaaagaa tatatttcca tgatgacaag gtatctgaag gtaaatatac
     7141 ttatggaaat aaaaactgta aataaataat ttaaattttc tatattcata tactatattt
     7201 tgtacttttt catataaata ttataactag tcttttattt tacttttgtt taacctaaag
     7261 ataatttact tttaatctat atgaattatc atataaataa tcagaaagtt atctttataa
     7321 attatagttt tagatttata atttataaaa tatttatgtt ctttgtaaaa ttttttagaa
     7381 gcttctaatg ttatgctata aaactatctt gagaagggct gattgaatgt ttaataaaat
     7441 atatgaaaag aaagaattta tagtttttca agttaaaaaa ggttatgtag tttataatac
     7501 tagaaagagt tttgaagaag gtcatacaca tttaaagcat tttgaagcag caaagacagc
     7561 tattgattta gcaataaata aaaagattcc tagaagcaaa gatggatatt atctgactag
     7621 tttaattcgc ataagtgatg atggttatta cattgataag ttaagcgaat tgttatatgt
     7681 tagagaacaa aaaggtaaaa aagaaaagta ctgtaattct ggttatcaga tgtaacaaga
     7741 ctagttgtga attataagta ccaatcataa gtacctttgg tcttaaaatc aaagagtatc
     7801 agtaaatcta taaaaaaaca acttactgat actcttttta attatatgat taatatttga
     7861 atttgataca aaattttata caaaagttta tgttatctat tctgattctt tgtctgcaaa
     7921 ttggctatta taaagcttct cataaaatcc acccttttcc attaattcat catgattccc
     7981 ctgctctata atacttccat tattcataac taaaatcaag tcagcattgc gaattgtaga
     8041 aagtctatgt gctataacaa aactagttct accattcata agatttctca ttgctttttg
     8101 aagcataagt tccagcctag tatcaacaga actcgtagct tcatcaagta tcaatattga
     8161 agggtctgat ataaaagctc tagctatggt taaaagctgt ttttccccta gagatatatt
     8221 agatgcttct tcatttaaaa acatattgta tccatctgga agagtggtta taaagtgatg
     8281 aacatttgct acttttgctg cttgtataat ttcttcttta gtagctccaa atctaccata
     8341 ttctatattt tcaaaaatgg ttccattaaa taaccatgta tcttgaagca ccataccaaa
     8401 cattgaacgc aaatctttac gtttcatatc tcttatatct actccatcaa ttttaatagc
     8461 acctttcttt acatcataaa acctcatcaa taagtttatt aatgttgttt tacctgctcc
     8521 agtaggtcca acaatagcta ccatctgacc actttttact tctgcattta aatcttctat
     8581 taaagttgaa ttttctccat atccaaaatt aacatgctca aatgtaacat ttccttttac
     8641 attttctatc ttaactggat tttcaacatc aggtatttcc tcttcttcgt ctaaaatttc
     8701 aaatacacgt tctatagctg caaaagaaga ttgtattact gtagataact gagtcatttg
     8761 tgaaagtggc tgatttatct gccatatata acgcacaaat gcttgtaaat ttcctactgt
     8821 tattcctcca cttactgcat atatagaacc gacaactgcc acagctgcaa ttccaaagta
     8881 agttactaat gaaaccatag gattcatcat acttgatata aattgtgcct taaatccatt
     8941 ttcacaaagt tcttgattta cttttttaaa ttcttttata gaatcttctt ctttaccata
     9001 tagttttatt tcattaaatc cagtatacat ttcttgtact ttcccattta attttccaag
     9061 agcattttgt tgcaatgaaa atctactttg agattttttt actacaaatt tagatacaaa
     9121 ataactaatt ggaattataa aaagagctat aagagccata tatatattaa ttgtaaacat
     9181 cattgaaagt gccaaaatta tgactaagat tgagtttaca atttgcataa aactctgctg
     9241 caatgcattt gatattgtat ctacatcatt tgatatacga cttaatacat ctccaaaact
     9301 attactatca aaataactaa taggcaatct tcttatttta ttttcgactt catttcttaa
     9361 atctctcatt gtgttttgaa tagcattggt aagtagaaaa cttgaagtat acgtaaaaat
     9421 tgcattggca aaatatatac atgctaaaat caccaatatt tttgttacat aatcaaaatt
     9481 tacggaagcc cctggtactc cttttgcgat actaattaca tctttagtca attgtgttat
     9541 tatcaatcct tcagttttag gtgcaagtgc attcatagta gctgctgaaa ttatacatat
     9601 aatagctata ataaaggaaa atttatattt ctttacaaat ggaagaagtc taccaattgt
     9661 tttcttaaaa cctttagact ttttcattat tctaattcct ccttttttaa ctgagatgtt
     9721 gcaatttcat agtatatttc acagtttttt aataattctt tatgagttcc cattcctaca
     9781 acttgtcctt cattgagtac tataatctta tcagcatcaa taatagaact aattctctgg
     9841 gcaacaatca atacaattgc atcttttgtt tccttcttca atttagcacg aagtattgca
     9901 tcagttttaa agtcaagtgc agaaaaacta tcatcaaaaa tgtatatttc aggtcttctt
     9961 ataatagccc ttgcaataga aagtctttgt ttttgacctc ctgatacatt tgctccacct
    10021 tcactaatca attcatcaaa ctttctaggt ttttttgata taaactcata tgcttgtgca
    10081 acttttgcgg aatattctaa ttctgactct cctgccttat gtttcccaaa tctaatatta
    10141 tttgctatgc taccagtaaa aagcagtgat ttttgaggta tgaatcctat cttttttctt
    10201 aaagctttta aatcatattc tcttatatct actccattta tcttaatact accttctgtt
    10261 acatcataaa atctaggtat caagttaatt agagtacttt tcccactacc agtacttcct
    10321 ataaaagcaa ctgtttcacc tgtttttgca gtaaatgaaa tatccttaag tacagaagct
    10381 tctccatctg gataggtaaa agttacatta tcaaattcta tgataccctt attttcagta
    10441 tccttaattc cattttcagg attttttatc aatggttctt catttaaaag ttcttttatt
    10501 ctatttgcag atacctctgc tcttggatac ataataaata ccattgaaaa aagcataatt
    10561 gaaaacatgg catggaaaag atattccaaa aatgcaacca actgtccaac ttgaagctct
    10621 ccaatattta tcttctcact tgaaatccaa aatacagcca aaacagctat atttaatagt
    10681 aaaaagaatg ctggttgagt aattgacata agcttaaata gtttcttaga aacattagca
    10741 taatatgtat ttgttttttc aaatcgctct gtttcataat catcatttcc aaaagctcta
    10801 attactctta ttccagttaa attttctctc gatataaggt ttaatttatc tagtcctttt
    10861 tgttgttttg aagatattgc ctgagatact tttgctatta ttgctactcc aataattata
    10921 aaaggtactg atatagccaa tactatagaa agttccacac ttgttctaat tgtcattatt
    10981 atacttataa tgaacataac tggagttaat aaggcagtcc ttagtagtat attaacaaat
    11041 tgttgaattt gaaatgcatc attcgttgtt cttgtaatca ttgaagaaat tccaaattta
    11101 ttgtattcag tatgtgaaaa ttcttgtgat ttctcaaata tgtcatttct tatatctctg
    11161 gttacacttg ttgatacctt agcagaacaa taacccaaca atatactacc tacaacccct
    11221 ataatagaaa taataacaat cactattccc atttgtttta tgtaagctat attctgattt
    11281 gcaataccat tgtcaattat tttagctatt atagttggaa tccccaactc gactaatgca
    11341 aaactaaata tagccagtat gtttaatact attaataact tataattctt taaataactt
    11401 aaaattaatt tcatattttt ctcctttctt aatttttgag atagtgtaat catgtaataa
    11461 tactaaattt ataaatgctt aattttataa aaaaaggaga aaagagttaa cgcactctct
    11521 tctccagcat attcttttta atacaccctc cgacaagtcg cttatatgtt aacatatttg
    11581 acaagtaatg tcaattcata tagccaaaag tcttttaaat gcttcatttc ataacattgt
    11641 aacaaattgg catgtaattt atttttgttt tttactgtat tccaatttta caagttctcc
    11701 aatattacta gctttcttaa aattcaaatt agtcttatct ataccagact taaatagtga
    11761 aatccctctc cccaatatta ttggcaatat atatatataa taatcatcaa ttaagttatc
    11821 tttcataaat aattttacta tatcgcctcc accaactatc caaatatctt ttttatcctt
    11881 ctcttttcca atttgctcaa ttaatttttt aggttctaaa ttaatttata gtgtgattat
    11941 tctatgtaaa catcactttt ttactcattc aataataccc tattaataaa tcctcaaact
    12001 aatttaaata aactttgcat aaaattaaaa atatattata taaataattt aaaaccacac
    12061 taacttattg aaaattctaa ttattacaaa taaatattgc tctctgttaa cgctagttct
    12121 ataatataat tataagctat taatattata aagacgatat tactaatata ataattataa
    12181 tacttatagt taatttactt ttgttgaaag gtggtaaata acatgaaaat ttcagaagtc
    12241 gctactccaa attttttgct agatttagac cagttagaaa agaatataga taaaattcaa
    12301 caaatttgta caaataataa taaacaactt tggcctatgc ttaagacaca taaaagtact
    12361 tacatagcga gacttcaaaa aaatgcaggt gctagtggtt ttctagttgg aacacttgat
    12421 gaaggtgaag ctctgataaa agcaggtttt gaagatatta tgttggctta tccttacatg
    12481 ggagaagtaa atataaatag aattgtgact atggcatcaa aaataaattt aatctgtgct
    12541 acagataata tagaatgtgc taaggcttat agtgaagctt tttctaaatc aaaaatagag
    12601 tgcaagctac ttattattgt agattgtggc ttacaccgtt ttggggttga accagagaaa
    12661 gtggttgaac ttgctactga aatttctaag ctagaaaaca taaagattgt tggtataagt
    12721 tcgcatccag gtcaagtgta tggttgtagt tctccagaag gtgttccaga tgtttgtgtt
    12781 caagaagatt cttctatgga gaaagcatac aaagctctaa ctgataatgg atttaatata
    12841 gaaattgtcg cttctggtag tactccaaca gttgaatctg aagctgcttc taaaactata
    12901 actgctgtaa gacctggaaa ctatgtatac tatgatgcta tacagatagg tttaggttgt
    12961 gctactgaag atatgtgtgc tcttactgtt gtgtgcactg taatctcaaa aaatagcagt
    13021 ggatactatt taattgattg tggaagtaag tgccttggac ttgataaagg tgcacatgga
    13081 aatagtagta ttgttggtta tggtagggta tgtggacatc cagaacttac tattgattca
    13141 ctttcagaag aagttggaaa aattaaagta aatggtgaaa ctgatataaa aattggtgat
    13201 agaataagaa ttatacctaa tcattcttgt tccactgcaa acttgacaag taatttatta
    13261 ggttttagag gagatacaat agaaaaagtc atagaagtag atattcgtga aaattcaaaa
    13321 caaatcatcc tttaaaaaca gatttattct gatattaaca tgaaagtata tttttcttaa
    13381 aattatttct aataactaat gttaatgttg gataaataaa aaacataaat tctagaaata
    13441 taaatttaaa agaagaggct gtctcaaaat agagataagc ctctctttca ttgttgaaat
    13501 tatgaaaata tacttgattt catacaaaaa gagtatctca tgaactaaaa agttcacttt
    13561 gagatactct ctttttttaa ttaatataca cattaattac tatcttagtt tattactata
    13621 tatcaattac tactcattaa tccttgtata tattaattct tatatatcat ttatagttag
    13681 gttataattt tatgttattt acattaatcc cataacagtg agtaaaactc ttactattaa
    13741 catccccact attgcatcaa atataggaac tgccaacagt aacattctat acttagtact
    13801 ggcatttgct acaagcacta ttctggcata atgaccaact agagtaccca ttaacataca
    13861 tggcataatt aatatggttg cttgtggtgc agtgattaga ccttgtgcaa ataagtttgc
    13921 agctgtagct gctcctgctg ccttagcaaa gaatgctgct atcaaaacta aaacagattc
    13981 cccaggtagt ccaaaaatac ccattactgg tccaaaaata tttcctaaaa tatcaactaa
    14041 accagttaat tgtaaaaact gcactattac ataacccatt atcatggctg gtaatatctg
    14101 ttcaacacct atgtaaaaac ctttttttgc tccccccata aatatctcaa cagcagtttt
    14161 cttaggttta ctatttacaa ttgcatttcc agtattttgt tgactcatac tacacagcct
    14221 ccttagcctt attcttttta tttcttacac ctatgattaa tctaactaga ttagcaccaa
    14281 gtattttaca gaatatctct ataaggatta ttggacctaa tgccaataat gctattggta
    14341 aaagtggagc ttgagtattt attgtgttca gtataacagc tgaaccagca tattgatatg
    14401 ctacaaatat agttctttca tcatctgtta tttccccact ttcaaataat tctttcgtca
    14461 ttattgaggc tacatctgaa ctagtaaatg aagatacaaa tgctattcct gctattccag
    14521 gtataccaag cagaggtcta agcaatggat taaatatctt tgatgccgct ttcattcctc
    14581 ccatagattc aactacatct ataagaccta cagcaaaaca gacagttgga atcaaagtca
    14641 gagcaaataa gaaaccatct tttgctcccg ttcctccttt acccataaag tctacaccat
    14701 ctgcaatagt accaaatgaa cctgtcagat tagcaaaatc taatgcttta aggaagcctt
    14761 gactatcttt aaacactcct gaaaataata ctatcaatac aaataaagat aaataccctt
    14821 tccatgttac cttattatct ccagctgtta catccatata aaatccccct ttatacctca
    14881 aatttatcta agtttaaaat aactgtagaa attaatttca ccctctcaaa catagaatct
    14941 actactgcat attctcttga tgtgtggttc cattcccctc ttacaccaaa tgaacagatt
    15001 gcgggaacgt ttgcaatagt caaataacta gcatctgaac tacctccaag tctcttagca
    15061 tttaattctc caaatccatt ttcttttgac acttcattta caaatgtatg aaatctcata
    15121 acatcttctg tagtttcaaa tggcatcatt tcacttataa aattaacttc tgtagaagtt
    15181 ccttctatgt aagtttcttt acatatctct ctaacttgtt ctttaacatt ctccatttct
    15241 tctacttttt caaatctaag gtctactttt atactacaat cttctggaat agaattttcc
    15301 actcttccac ccttaatcac acttacactt actgtagttc caacatctaa attagtcaat
    15361 ttttgtatgc gtagtatctt attagccatt tcttctatag catttcttcc accttcaaaa
    15421 tcattacctg cgtgtgtttc tacacctttt acatgtatat tacatcctat tcttcctttt
    15481 ctacctacac acaaactatt atctactaat ccagtttcca tattaaaagc acaaagacca
    15541 ccttttgctt ccctcaatat aacatctgca cctgttgaat ccttatgtcc tatctcttca
    15601 tctccagaaa atactatttt tattggtctt tctttgtatc ctattttatt taatgcttta
    15661 ataacatata aggaaattat tataccaccc ttcatatcta aaacacctgg gccatatgct
    15721 tttccttcta ttattttaaa tggattctct ccaaatgtac ctgtttcaaa gacagtatcc
    15781 atgtgacctg aaaaaattat aggcttttta tttatattag aaccaagtgt acctatcaat
    15841 gtactaccat tatctccaac atctactaac tcgcaatcta aaccttcttt ttcaaactca
    15901 aactttaatc tcttagccaa tttatttacg ctttctttac aatgtgtata gctttctata
    15961 ttaacaatct ctttccataa tgaaactatt tcttctctat tctcatcaac aaacttagaa
    16021 atttcattta aatatgtatt cataatcttc tcctttattt tcaaataaaa tgtatttctt
    16081 tcctaaaatc taagtttatt ttaggaaatc ttaaaagact agtccttaat tacaaaatag
    16141 cacaattatt cttgacagtc aacatatttt tcagtctttt ttatattttc tgatttttct
    16201 ttaaattttc cttttgtaaa ataaattgac gcgttttatc tactattata aaatgaggtt
    16261 ataaattgat tgattagtta ctatactctc gaaattttaa aggaggtttt atgaaatata
    16321 aaattggttt tttgacaaca tcttatttta tgtcagataa gtttaaacaa gctcttaaag
    16381 aattaaatga tacttgtgaa attacattta ttgagctcaa aggggagaat ccttttaata
    16441 atttacctaa tatatactat gagcaagtag ataattttga tggatttgta tgcagtggta
    16501 tagttccata tagtgaactt ataataaata taaaagacat aaaagttcca ttaaattttt
    16561 taaagcttga tgaaagagat ttttataaat acttattcaa attattaaat agccaaaaag
    16621 atattgactt tacaaaatca tttatggatt ttttaagaga ggacaacaat tattatgata
    16681 tatattcatt aatagactct aataaatgtc catatacaat taaagatttt aatatccctc
    16741 aacctgtata tgactttaaa aaattaaatg ataaattatt ggaaatacat ttagacttat
    16801 tgcgagataa taagattaac ctttctttta ctagaaatta catcattagt tgtgaactta
    16861 ataaacttgg atatgattgt atttacatgg ttccatctac agaatcaatc ctgaatacat
    16921 ttaaatctct ggtgaatgaa ataacattac aaaacttaga caaaaataaa tctgcaactt
    16981 gtatagttac agtaaatagt tcagagtaca taaatgaaga tttgatattt aaaaatgatg
    17041 agatacaaaa tcaaatatat aacactatat taaattctct atcaagacat ggattttatg
    17101 gagttcaggt caaaaaaaat gatatgaaaa tagagataca cactactaaa gaaatgttaa
    17161 acaatatgac caataactat acagattttt ttatttcaga agatttaaaa gaaattaaat
    17221 atagcttaaa tataggttgg ggcattggaa atacaaatat tcatgcagag caaaatgctc
    17281 gtcaagctaa tggtaaatct gcttctttga atggaaactg tacttttata gtaaatgata
    17341 ctaatgatac aataggccct ttatattcaa ataaaaattc taataatatt gaagatagct
    17401 caatagccaa taaagttgct tcttttatac ctctatctaa tacaaatgta tctaaaatca
    17461 tgtgtatgat taatgataga aattcaaata atgtgtcagc agaaatatta tcaaactata
    17521 tgaacataac tcttagaagt gctaatagaa tattgagtat cttatataaa gcaggaattg
    17581 caactattgt aaatacaaaa ctcgataatc aaagaggaag gcccaaaaaa atatataaag
    17641 ttgatttctt atcttttcta aataagatgc agaaattaaa ttcttaatat ttaatttttt
    17701 aataagaaca atgtattttc tctaatttta aagaatcaaa atgtttaaat tttattagaa
    17761 tatacaactt tttactttaa aatacctaaa ccttttatca gtgaaataaa ccataatata
    17821 tcgtaactta ttagaaaaac aaaataattt catatacaaa taataaaata gccactacaa
    17881 tccataattt gcagtggcta ctttttacac tatcacttat tacttaattt ttaaaaatta
    17941 attgtatttt ttaaataatt tatacatacc tattatcagt aaagcaataa atacaagtat
    18001 atctataaaa ataattattg taacatgtct ggcaatattg taaataaaaa gtatagagaa
    18061 tatttctata gacaacgcta caaaacacat aaaattcgtt aaataatctg caatagtgtc
    18121 actataaaaa gcatgtattt gtaaccatct ccatataaat ggacgtaaaa ggattctgaa
    18181 tacaacacaa atgacagggt aggcataaat aaatttttta tctacataat tagctacacc
    18241 attattccat tggataggaa tttgaggtgg caactttgga aatactgtta ttgcaattta
    18301 aacactacct ctctattcta ttaatttata actataatat agtcttaaa
//
LOCUS       DAJMZY010000084        18245 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.084, whole genome shotgun sequence.
ACCESSION   DAJMZY010000084 DAJMZY010000000
VERSION     DAJMZY010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18245)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18245)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18245
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.084"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            complement(221..907)
                     /locus_tag="OE968_002737"
     CDS             complement(221..907)
                     /locus_tag="OE968_002737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HCP7220007.1"
                     /translation="MFGVIANSLAIAGGCIVGLIIKGGLPQRVSDTIMNGIALCVLYI
                     GISGALEGKNTLVTIISVAVGALIGELIDIDKWVNKLGAFLQSKFSKGNKKDSIAEGF
                     ISSSLLFCIGAMAVVGSLESGLTGSHDTLFVKSVIDGIASIIFTASLGIGVMFSAISV
                     FLYEGIICVGASFLNGFLSDPVVTEMTAAGSLLIIGLGLNVLKLTNIKVANLLPAIFI
                     PILFGVFGII"
     gene            complement(956..1489)
                     /locus_tag="OE968_002738"
     CDS             complement(956..1489)
                     /locus_tag="OE968_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HCP7220008.1"
                     /translation="MSDLNNKKEQDENESSMNETKIYDILDKLNVEYDVVEHEAVYTA
                     EQLVILDGITKGCQCKNLFLRNAKGNKYYLIVVKGEKQVDLNSLKDKIGSSRLSFASP
                     ERLYNVLKLLPGSVNPFSLINDTERKVELYIDKDVIKEDYLNFHPNINTKTVNISRKG
                     FEEFLEYLKYPIQSIDV"
     gene            complement(1533..2165)
                     /locus_tag="OE968_002739"
     CDS             complement(1533..2165)
                     /locus_tag="OE968_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclase family protein"
                     /protein_id="HCP7220009.1"
                     /translation="MKVFDLTHVTHNDMPVYAEPNRPDIKKVAIIEENGYQETLISVF
                     SHNGTHMDSPRHMYTKGETLDKLDIENFVGKAYVLELEKGNENIELEYLKKYEDEIKN
                     SDFIIFKSGWSKFWDKKQYYVGYPTLTKEAANYIANTNIKGIGIDMLSVDRYDTSVFE
                     VHHILFEKGKIIIENLTNLENVPEKFLFIAAPFKYNDADGAPVRAIAIVE"
     gene            complement(2255..3334)
                     /locus_tag="OE968_002740"
     CDS             complement(2255..3334)
                     /locus_tag="OE968_002740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
                     /protein_id="HCP7220010.1"
                     /translation="MKIAIFLGAGASAAENLPIQNELFSEYFKKLNPTNYNTKMNREL
                     YIFFKQMFNIDIVKDNIDNANFPTFEEVLGLLDLAEQRKEAFRNFGLENLNNRSDSIR
                     FLRQYLILLMAEAIHNTPRTDNKYHKLLVENLLENDLLLDTTFISANYDIHIDNTVTG
                     LRDKNDLPIMLDYGVEFTNFKEELNWRKPKEPLIKLYKIHGSLNWLYCPICNSVTLTP
                     HEGGVMKLIENSSETKCLECGELTEPIIVPPTYFKNMSNIFLSNVWNETEKTLRDTDL
                     LIFCGYSFPEADMHIKYMLKRVQTNRKKPPLKIMVFNNHSQKQRITLKKEEGRYKRFL
                     GEDVIFTDNSFQDFSVNPLRFIKNI"
     gene            complement(3467..4813)
                     /gene="pepV"
                     /locus_tag="OE968_002741"
     CDS             complement(3467..4813)
                     /gene="pepV"
                     /locus_tag="OE968_002741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HCP7220011.1"
                     /translation="MKEQIKEKVNSLQDEMISSIQESVKIPSVISEATENCPFGENVD
                     KALRGILDLCKSLGFKTVYKDGYYGYAEIGQGEKMIGILGHVDVVPEGDLESWNYPPF
                     EAVLEDGKLYGRGTQDDKGPTISAIYAVKALMDLNVDFNKRIRFIFGADEENLWRCIN
                     KYKENNEEIPNYGFTPDSRFPITNAEKGLLQVHLTCDSKSDIELSVGKALNAVPGKAI
                     YIGKYSDKLKKELDKLNFEYTVEGNKICIIGKSVHSAASDTGINAVARLCIALNNIGI
                     DSNIIKFLAEVIGEDANGNNIIPNCKDDVSGKLTVNIGRVTIDNEKEFAGIDVRIPVT
                     YKKDDFVKELKKMTDKYNLNYEEYDFLDSIYVPEDTLLVKTLRKVYEEETGLDGTPLS
                     SGGATYARALDNCVAFGAIFPGKPETEHQANEYLIVEDIIKATQIYALSIYELLKI"
     gene            complement(4882..6162)
                     /locus_tag="OE968_002742"
     CDS             complement(4882..6162)
                     /locus_tag="OE968_002742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine gamma-lyase family protein"
                     /protein_id="HCP7220012.1"
                     /translation="MLNETKELLKDYYGIDDDTFKLSQEIMEEIKDKFEEIKEIREYN
                     QYKVLKAMQESKLSDMHFNWTTGYGYNDIGREKIEEIYSKVFNTEDALVRPIIVNGTH
                     ALTLCIQGIVRPGDEILSVTGRPYDTLEGVIGIREEKGSLKEYGVTYDDVDFLEDGNL
                     DLEGIKNKINDRTKLVMIQRSKGYSWRKSLSISDIKEAIEVIKSVKPEAIVMVDNCYG
                     EFLDTKEPTDVGADVMAGSLIKNPGGGLALTGGYIAGRKDLIELISYRMTSPGIGKEC
                     GLTFGTTRNVLQGFFLAPYIVSQAVMGAIFCSRAFEKLGYDVLPKYDDLRSDIIQCIR
                     LNNADEVISFCEGIQEAAPVDSYVKPVPWDMPGYESEVIMAAGAFIQGSSIELSADAP
                     IRPPYNVYFQGGLTFDHSKMGTLKAIEFIKKLKK"
     gene            complement(6289..6549)
                     /gene="hfq"
                     /locus_tag="OE968_002743"
     CDS             complement(6289..6549)
                     /gene="hfq"
                     /locus_tag="OE968_002743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA chaperone Hfq"
                     /protein_id="HCP7220013.1"
                     /translation="MKNTVLNLQDLFLNNARKERIPVTIYLVNGVQVKGLVKGFDSYI
                     ILIEGDNRQQNMIYKHAVSTIQPGKYINLTNQNQNNNNNNNR"
     gene            complement(6663..7598)
                     /gene="miaA"
                     /locus_tag="OE968_002744"
     CDS             complement(6663..7598)
                     /gene="miaA"
                     /locus_tag="OE968_002744"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HCP7220014.1"
                     /translation="MKKIPLIILTGPTAVGKTDLSIKLAKDMNAEIISADSMQIYEYM
                     DIGSAKVTEEEMQGVKHYLIDEVKPDYPFSVSEFQQRAKKYIHEINEKEKCVLVTGGT
                     GLYLNSLIYNMDFAQSDANNELREELQKQLAEKGIDYMHNKLKELDEESANRIHKNNT
                     KRVIRALEVCLSGKKMNDFSSDLKFNEEYQPIIIVLNRDREHLYQRINMRVDIMIKNG
                     LVEEAKKLLSMGFKKDMISMQGIGYKEILKYLDGEYTYEEAIEIIKRDSRRYAKRQIT
                     WFKRYKTAKWFDLDQYENIDELKNEIILYIKDSIK"
     gene            complement(7636..9603)
                     /gene="mutL"
                     /locus_tag="OE968_002745"
     CDS             complement(7636..9603)
                     /gene="mutL"
                     /locus_tag="OE968_002745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HCP7220015.1"
                     /translation="MKNIINILDDLTINKIAAGEVVERPSSVVKELIENSIDAGANKI
                     SIDIIDGGKSLIKITDNGIGIPSSEVEKSFLRHATSKIKKIDDLYDLYSLGFRGEALA
                     SISAVSKLEMTTKTKDEIIGTKIYVEGGKIISKEPIGSTNGTTIIIKDIFFNTPARQK
                     FLKSTHAETINISDLINKLAIGNPNIQFKYTNNNKQMLNTPGDGKLVNTIRSIYGKEI
                     TENIIDVEFKCNHFKMNGYIGNNNIYRSNKNLQHIYINKRFVKSKIIIDAITESYKSI
                     IPIGKHAVCFLNIEVDPSCIDVNIHPNKLEIKFEKEQEVYIELRDFLKVKLIHSNLIG
                     KYATYSDKKTQPRIAINSREKSTDYKLRNNDLLESTPKNSNITKGKDEVIEVVTLSSE
                     KPINEFQSVSEVLNASVEDDVKNINYLSEDSANDNIQEEFQVDGIKNEGNYYLGDSIK
                     DSEEEYLCSSKRKFSLYGYFVIGVVFNTYIILSKDDSMYLLDQHAAHERILYERYMEK
                     FYRQDINMQILLDPVVIEVSNIDMLQIENNLELFMKFGFELEIFGNNHIMVRCVPTIF
                     GVPETEKFILQIIDNIEEITSNYDLKGERFASMACRSAIKANDKIYDIEIKSLLEQLE
                     KCENPFTCPHGRPIMVEISKTEIEKMFKRIM"
     gene            complement(9614..12457)
                     /gene="mutS"
                     /locus_tag="OE968_002746"
     CDS             complement(9614..12457)
                     /gene="mutS"
                     /locus_tag="OE968_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HCP7220016.1"
                     /translation="MQIDMNKLTPMMKQYLEVKNRYKDCILFFRLGDFYEMFFEDALV
                     ASKALEIALTGKACGLEERAPMCGVPFHSANSYISKLVENGYKVAIGEQMEDPSTAKG
                     IVRREVIRVITPGTVLDGNLLENKKNNYLLSLYKDGTNIGLTYVDISTGETNATCLNE
                     DKVIEEIAKIHPTEIIINDLDFIEKLRDIATVSNIYINESFSDNYLDINILKEYFPDV
                     YLQKLKFDDKGLIKSSLSILLNYIYNTQKQITSNINNINIYNSSEYMVLDMFTRTNLE
                     LTQTIRGNKKKGSLLHVLDKTSTAMGGRLLRKYVEEPLINKSKIENRLDVIEEIKDDF
                     ILREDLNDILKNIYDIERICGKIAFERVTPKELIHLKNSIEKLPNLKDTINLSNAKIL
                     KEYVSEMDKLDDIYNLIDEAILEEPTITIKDGNIIKSDFSDELKELREISKNGAFLVK
                     EIENREREKTGVKSLKIGFNKVFGYYIEITKANFKQAKLDETYIRKQTLSNAERYITP
                     ELKEIEEKILHAEEKIKSLEYEIFVEIRDTIYKNIDRIQKVAKTIANIDVFVSLATVA
                     HINNYVKPAINENNKLDIRNGRHPVVENIVGEENFVPNDTYLNRGENIINIITGPNMS
                     GKSTYMRQTAIIALMAHIGSFVPAESADIPILDRIFTRVGASDDLSQGQSTFMVEMNE
                     VSLILKNATERSLVILDEIGRGTSTYDGISLAWSIVEYIQKNIRCKTLFATHYHELTD
                     LEEEFKEVKNYSIAVKEDGEGIIFLRKIIPQGADKSYGIYVAKLAKLPDEVIERAKYI
                     LKDLEKNHVYNSVAINGDKENNNIINSNLDEELVKVNQSNFKNKYESLKIEHELIVKD
                     YKHIKKDYDKLNSKFKALNDEVALMKQNDDKEKINQEDSVKEVALTQISFDSVNRDIL
                     SEEILNLDILNMTPLDAINSLYNLQRKAKEIKS"
     gene            complement(12618..13352)
                     /locus_tag="OE968_002747"
     CDS             complement(12618..13352)
                     /locus_tag="OE968_002747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCP7220017.1"
                     /translation="MLTQMNFYHNKKVKVSIENVSKTYKDIEVLKDISIDVYEGEFVS
                     ILGPSGCGKSTIFNIITKLTDYDSGKVNINGKYSYMYQKDLLLPYKTIIDNVSLPLIL
                     KKEKKSKARSMVKPYFEVFGLSGYEDKYPSELSGGMRQRANFLRTFINSNDIMLLDEP
                     FGALDSLTKTSMQKWLLDVKKKVNSTILLITHDIDEAIMLSNRIYVISKKPSIVKKEF
                     VIDSRKLNEDNLENIIKLKKEIISLL"
     gene            complement(13321..14334)
                     /locus_tag="OE968_002748"
     CDS             complement(13321..14334)
                     /locus_tag="OE968_002748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HCP7220018.1"
                     /translation="MNFKKLGILGLVSVFTLATITGCSSNNNKDKNNDKDTSSKKVTM
                     VLDWTPNTNHTGLFVALDKGYYKEEGLDVEIVQPPESGAETLVATGKADFGISYQEQV
                     TYAKTSEDPLPIKAVATVIQHNTSGFASPKEKNITTAKDFEGKTYGGWGSPSEEAVFK
                     AVMKKNGADFNKLKIVNTGQDDFFAAMKTVDFAWIFEGWDAVKADLIGYDLNFIPVKD
                     LDERLDYYTPLIISNETVLKNNPELAKKFLKATTKGYEYAIKNPEESAKILVKHAPEV
                     DEKLALKSQEYLASKYKDDAPRWGEMKDSVWNNYTSFLKEYKLIDKDMKASDAYTNEF
                     LPQ"
     gene            complement(14356..15126)
                     /locus_tag="OE968_002749"
     CDS             complement(14356..15126)
                     /locus_tag="OE968_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCP7220019.1"
                     /translation="MKNLEIIDKVKDSIYPIATFLFILILWQSMVGVLEVPQYILPTP
                     VDIINVFFKDYQNLSIHAVVTIGEAILGFIVAIIISLVIGILMDFVSIIKKCLYPIML
                     VTQMIPTIIIAPLFMIWFGFGTMPKVLMVMLTCFFPILISFVDGIENIDKDYLNLFKT
                     MDSNKVNTFIHLKFPMAMDKFFSGLKISATYAVMAATVAEWLGGTKGLGVYMLRSKSA
                     YALDKVFASTILVVIFSLMFVGIVQAVKKVVIRHRLID"
     gene            complement(15101..15391)
                     /locus_tag="OE968_002750"
     CDS             complement(15101..15391)
                     /locus_tag="OE968_002750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MTH1187 family thiamine-binding protein"
                     /protein_id="HCP7220020.1"
                     /translation="MVIADIAVMPLRPYKGEEEMYKVVDACIAEIEKSGLKCEIGAMS
                     TTVEGDFDEVFELLKKVHKIPFNLGCERVITVARVDEKAGGLTIDEKLRNHR"
     regulatory      complement(15522..15621)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     regulatory      16241..16330
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            16383..16559
                     /locus_tag="OE968_002751"
     CDS             16383..16559
                     /locus_tag="OE968_002751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220021.1"
                     /translation="MFMDKMDRCTHILTAYICSSRDYCNFIDTQLNDFILEYGENVVE
                     SCLHQVMVLVSRYN"
     gene            complement(16674..17030)
                     /locus_tag="OE968_002752"
     CDS             complement(16674..17030)
                     /locus_tag="OE968_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCP7220022.1"
                     /translation="MDIDNNFEEFPNIEERQKDFNCSIGFTMTVIGSKWRAIILWHIL
                     KQEPIRYSQLKKEVVHISHKILSQELKYLERDGLIKRISYPTIPPKVEYLSTKRGKSL
                     ESILLELCNWGKQYMR"
     gene            17286..18199
                     /locus_tag="OE968_002753"
                     /pseudo
     CDS             17286..18199
                     /locus_tag="OE968_002753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007061260.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family isomerase"
BASE COUNT         5861 a         3081 c         1946 g         7357 t
ORIGIN      
        1 tagctccatt tacatcaaaa gtaatcattg agttttaacc tccccattag tttcatcaat
       61 aaaataaatt taatataaac tttataatca taatattaaa cttatttata ctataattat
      121 taatttgatg ataaaagcta ttttccttct aaataaaaaa tttgtctaaa gtttctaaaa
      181 aatttagaca aatcttaggt tattactctt taaattattt ttaaattatt ccaaatacgc
      241 caaataatat tggtataaat atagctggta acaaattggc tacttttata ttcgttaatt
      301 taagtacatt tagaccaagt cctataatta ataaacttcc agctgctgtc atttctgtga
      361 ctacaggatc acttaaaaat ccatttaaaa atgatgctcc cacacatata ataccttcat
      421 acaaaaatac agatattgca gaaaacatta cacctatacc taaagaagca gtaaatataa
      481 ttgaagctat tccatctata acagatttta caaataaagt atcatgactt cctgtaagac
      541 cactttctaa tgaaccaact actgccatgg ctcctataca gaataataaa ctagatgata
      601 taaaaccctc tgctatagaa tcttttttat ttcctttaga aaatttactt tgtaaaaaag
      661 cacccaactt atttacccat ttgtcaatat ctattaattc tcctatcaga gcacctacag
      721 ctacggatat tattgtcact aatgtgtttt ttccttctag tgctcctgat ataccaatgt
      781 acaatacaca taaagcaatt ccattcatta tagtatcgct tactctttga ggtaatcctc
      841 cttttattat aagacctact atacatccac ctgcaattgc tagactattt gctattactc
      901 caaacatttt ttctcccctc gattagctaa ttgaaattta tcctattatt aaaacctaaa
      961 catctatact ttgtattgga tattttaaat attccaaaaa ttcttcaaaa ccttttctag
     1021 atatatttac agttttagta tttatgttag gatgaaaatt taagtaatct tctttaatta
     1081 catctttatc tatgtaaagc tcaacttttc tttctgtatc atttattaat gaaaaaggat
     1141 ttacacttcc aggaagaagt ttaagtacat tgtatagtct ttcaggtgaa gcaaacgata
     1201 atctagaact tcctatctta tctttaagtg agtttaaatc aacttgtttt tctcctttaa
     1261 ctacaataag ataatactta tttcctttgg catttcttaa aaataaattt ttacattgac
     1321 acccctttgt tattccatct aaaatgacta attgctctgc tgtatataca gcttcatgct
     1381 ctactacatc atattcaaca tttaatttat ccaaaatatc atatatttta gtttcattca
     1441 tgctagattc attttcatct tgttcttttt tattatttaa atcactcata cttttctcct
     1501 taaacacttc atcataatat cattgtgagg tattattcta ctatagctat tgctcttact
     1561 ggagctccat cagcatcatt atacttaaat ggtgctgcta taaatagaaa tttttctgga
     1621 acattttcta aatttgtaag attttctatg attatttttc ctttttcaaa taaaatatga
     1681 tgcacttcaa atactgatgt gtcatatcta tccactgata gcatatctat tcctatgcct
     1741 tttatattag tattagctat atagtttgca gcttcttttg ttaatgtagg ataacctaca
     1801 tagtactgct ttttatccca aaattttgac caacctgatt taaatattat aaaatcacta
     1861 ttttttattt catcttcata tttttttaga tattctaatt ctatattctc atttcccttt
     1921 tcaagttcca atacataagc ttttccaaca aaattttcta tatccaactt atctagggtc
     1981 tcacctttag tatacatatg tcttggtgaa tccatatgag ttccattgtg agaaaataca
     2041 ctaattaatg tttcttgata accattttct tcaataatag ctactttctt gatatctggt
     2101 ctattaggct ctgcatatac aggcatgtca ttatgtgtca catgagttaa atcaaaaacc
     2161 ttcatcttta tataccccct atgtttttat tttctattat atacctaaat tcattttatt
     2221 tctatcagat tttattccat tatataccat actactatat attttttata aacctcaagg
     2281 gatttaccga aaaatcttgg aaagaattat cagtaaatat aacatcttca cccaaaaaac
     2341 gtttatacct tccttcttct ttctttaaag taattctctg tttttgtgaa tgattattaa
     2401 aaaccattat cttaagagga ggtttttttc tattagtctg cactcttttt aacatgtatt
     2461 ttatgtgcat atcagcttca ggaaatgaat atccacaaaa tattaaaagg tcagtatctc
     2521 ttaaagtttt ttctgtttca ttccaaacat tacttaaaaa tatgtttgac atattcttaa
     2581 aatatgttgg tggcactata ataggttctg ttaactcacc acactctaaa cattttgtct
     2641 ctgaactatt ttcaataagc ttcatgacac caccttcatg tggtgtaaga gttacactat
     2701 tacaaatggg gcaataaagc caattcaatg acccatgtat cttatataat ttgattaatg
     2761 gttcttttgg ttttctccaa tttaactcct ctttaaaatt tgtaaactcc acaccataat
     2821 caagcataat tggcaaatca ttcttatctc ttaatccagt aactgtattg tctatatgta
     2881 tatcataatt tgcactaata aaagtagtat caagaagcaa atcattttcc aaaagatttt
     2941 caactaaaag tttatgatat ttattatctg ttctaggtgt attatgaatt gcttcagcca
     3001 ttagcagtat taaatattgt cttaaaaaac gtatactatc acttctgtta tttagatttt
     3061 ctagtccaaa atttctaaat gcttcttttc tttgttctgc taagtctaaa agacctaaaa
     3121 cttcttcaaa ggtaggaaaa tttgcattat ctatattatc ttttactata tcaatattga
     3181 acatctgttt aaagaaaata tacaattctc tattcatttt ggtattataa tttgtgggat
     3241 ttagtttttt aaaatattcg ctaaaaagtt cattttgaat aggtagattc tctgctgctg
     3301 aagctcctgc tcctaaaaat attgctattt tcatatagtt cctcctaata taaatattac
     3361 tcctattttt atatccatta aatatccata tcatttattt tatgatacaa caataaagct
     3421 gtcttttact agaaaaaatc ctattacaag acagccttat attatattaa atctttaata
     3481 attcgtaaat agaaagagca tatatttgag tagcttttat aatatcctct actattaagt
     3541 attcattagc ttggtgttct gtttctggtt ttcctggaaa aatagctcca aatgcaacac
     3601 aattatctaa agctcttgcg tatgttgctc ctccagatga aagtggtgtt ccatcaagac
     3661 cagtttcttc ttcatatact tttctaagtg tcttaacaag aagagtatct tctggaacat
     3721 agattgaatc caagaaatca tattcttcat aatttaaatt gtatttatct gtcattttct
     3781 ttaactcttt tacaaaatca tcctttttgt atgttactgg aatccttaca tctattcctg
     3841 caaattcttt ttcgttatca atagttactc tacctatatt tactgttagt ttacctgata
     3901 catcatcctt gcaattagga attatattgt ttccattagc atcttcacca ataacttctg
     3961 ctaaaaactt aattatatta gaatctatac ctatattatt aagagctata caaagtctag
     4021 ccactgcatt tataccagta tcacttgctg ctgaatggac actttttcca attatacaga
     4081 ttttattacc ttcaacagta tactcaaaat ttaatttatc aagttctttt tttaatttat
     4141 cagagtattt tccaatatag attgctttac ctggaactgc atttaaagcc tttccaactg
     4201 acaactctat atcacttttg ctatcacaag tcaaatgaac ttgtaaaaga cctttctctg
     4261 catttgttat tgggaatcta gaatctggag taaatccata gtttggtatt tcttcattat
     4321 tttctttata tttatttata catctccaaa gattttcttc atcagcccca aaaatgaatc
     4381 ttatcctctt attaaagtct acatttaaat ccataagagc tttcactgca taaattgctg
     4441 atattgtagg tcctttatca tcttgtgttc ctcttccata caatttacca tcttctaaaa
     4501 cagcttcaaa tggagggtaa ttccagcttt ctaaatcacc ttctggaacc acatcaacgt
     4561 gaccaagtat acctatcatt ttttcacctt gtcctatttc tgcatatcca taatatccat
     4621 ctttgtatac tgtcttaaat cctaaagatt tacataagtc taatatacct cttaaagctt
     4681 tatctacatt ttcaccaaat gggcaatttt cagttgcttc agatataaca ctaggtattt
     4741 ttacactttc ttgtattgaa gaaatcattt catcttgtag agaatttact ttttctttaa
     4801 tttgctcttt catattatca cccttcaatt ttcatcataa tatactaata aatattttga
     4861 ccttttaaaa aaaaaatatg cttatttttt cagttttttt ataaattcaa tcgcttttaa
     4921 agtccccatt tttgaatggt caaatgtaag tccaccttga aaataaacat tataaggagg
     4981 tcttattgga gcatctgcac ttaattctat agaagaacct tgtataaatg ctcctgctgc
     5041 cattatgact tcactttcgt atccaggcat gtcccaagga acaggtttta cataagaatc
     5101 gactggtgca gcttcttgta taccttcaca aaaacttatt acttcatcag cattattaag
     5161 tctaatacat tgaataatat cacttcttaa gtcatcatat tttggtaata catcatatcc
     5221 taatttttca aaagctcttg agcaaaagat agctcccatt acagcctgag atactatata
     5281 aggcgccaag aaaaaaccct gaagtacatt tctagttgtt ccaaaagtaa gaccacattc
     5341 ttttcctatt ccaggagaag tcattctata agatataagc tcaatcaaat cttttctacc
     5401 agctatatat ccacctgtca atgcaagccc accaccagga ttttttatta aagagccagc
     5461 cataacatct gctccaacat cagtaggctc tttggtatct aaaaactcac cataacaatt
     5521 atcaaccatt actatagctt ctggtttaac agactttatt acttctatag cttcttttat
     5581 atcactaatt gaaagtgatt ttctccaaga atatcctttt gacctttgta tcataacgag
     5641 tttagttcta tcatttattt tgtttttaat tccttctaaa tctaagtttc catcctctaa
     5701 aaaatctaca tcatcatatg taacaccata ctctttcaat gaaccttttt cttctcttat
     5761 gcctataact ccctctaaag tatcatatgg tctaccagta acagataaaa tttcatctcc
     5821 tggtctaact ataccttgta tacataaagt aagtgcatgt gtaccattta caattattgg
     5881 tcttacaaga gcatcttctg tattaaatac tttagaataa atttcctcta ttttttcacg
     5941 accaatatca ttatatccat atcctgtagt ccagttaaag tgcatatcac ttagtttaga
     6001 ttcttgcata gcttttaaaa ctttatattg attatattct cttatttctt ttatttcttc
     6061 aaacttatct tttatttctt ccattatttc ttgcgatagt ttaaaagtat catcatctat
     6121 tccatagtag tcttttaata attcttttgt ctcattaagc attttatcac ctgtctcttt
     6181 attattttat ttaaacatgt aaaggagact attttactaa aacaaataaa ttatagttta
     6241 taagttagta taagtctcct ctcaatcatc ttaaattaaa ttaattatct atctgttgtt
     6301 attattattg ttgttttggt tttgatttgt tagattaata tactttccag gttgtatagt
     6361 tgatacagca tgtttataaa tcatgttttg ttgtctatta tccccttcta ttaatattat
     6421 ataactatca aaccccttta caagcccttt aacttgcact ccattaacta aatatatagt
     6481 aacaggtatc ctttctttcc ttgcattatt taaaaacaaa tcttgtaaat ttaaaactgt
     6541 atttttcatt agatttgtac cctcccaaga ttaaattgaa cttctaaaat attcctacct
     6601 tatattctat ataagttatg acaaattttc aatattaagt tgtatactta aaaatttata
     6661 tattatttta tagaatcttt aatatataag attatttcat tttttaattc gtctatattt
     6721 tcatattggt ctaaatcaaa ccattttgct gttttatatc ttttaaacca tgttatctga
     6781 cgttttgcat accttctaga atctctttta attatttcaa tagcttcttc gtatgtatat
     6841 tctccatcca gatactttaa tatctcttta taacctatac cttgcattga tatcatatct
     6901 tttttaaatc ccatacttaa aagttttttt gcctcttcaa ccaatccatt tttaatcata
     6961 atatcaactc tcatatttat tctttgatac aaatgttctc tatctctatt tagaactatt
     7021 attattggtt gatattcttc attaaatttt aaatcacttg aaaaatcatt cattttctta
     7081 ccacttagac aaacttcaag agctcttatg acccttttag tattgttttt atggattcta
     7141 ttagcagatt cttcatcaag ttcttttaac ttattatgca tgtaatctat tcccttttca
     7201 gcaagctgtt tttgaagttc ttctcttaat tcattattgg catcagattg tgcaaaatcc
     7261 atattatata ttaaagagtt taaataaagt cctgtgcctc cagttactaa aacacatttt
     7321 tccttttcat ttatttcatg tatatatttt tttgctcttt gttgaaactc tgaaactgaa
     7381 aatggatagt caggcttaac ttcatctata aggtaatgct tcactccttg catctcttcc
     7441 tctgtaactt ttgcacttcc aatatccata tattcatata tttgcataga atcagctgaa
     7501 attatctctg cattcatatc ttttgctaat tttattgaca aatctgtttt tccaacagca
     7561 gttggacctg taagtattat aagtggtatt tttttcataa cattcctttc catatatttt
     7621 aaatatccaa atattttaca taattctttt aaacattttt tctatttctg tcttagatat
     7681 ttcgaccatt ataggtcttc catgaggaca tgtaaatgga ttctcacact tttctagctg
     7741 ttccaataaa ctttttattt caatatcgta tattttatca tttgctttta tagcagacct
     7801 acatgccata gatgcaaatc tctctccttt taaatcataa ttacttgtaa tttcttctat
     7861 attatcaatt atttgaagta taaatttctc agtttcaggt actccaaata tagtaggaac
     7921 acatcttacc attatatgat tattgccaaa aatttctagc tcaaaaccaa atttcataaa
     7981 taactccaag ttattttcaa tttgaagcat atctatattt gatacttcaa taaccactgg
     8041 gtctaaaagt atttgcatat ttatatcttg tctatagaac ttctccatat atctttcata
     8101 tagtattctt tcatgtgcag catgttggtc caacaaatac atagaatcgt ctttgctcaa
     8161 aattatataa gtattaaata caactccaat tacaaaatat ccgtataaag aaaacttgcg
     8221 ttttgaacta cacaagtatt cttcttcact gtccttaata ctatctccta agtaataatt
     8281 tccttcattt ttaattccat caacttgaaa ctcttcttgt atattatcat ttgcactatc
     8341 ttcacttaga taattaatgt tttttacatc atcttctaca cttgcattta ggacttcact
     8401 tactgattga aattcattta ttggtttttc acttgataaa gtaacaactt caatgacttc
     8461 atccttacct ttagtaatat tactattttt aggagtagat tctaataaat cattatttct
     8521 taatttataa tctgtacttt tttctctact gttaatagcg attctaggtt gtgttttttt
     8581 atcactataa gtagcatatt ttccaataag atttgagtgt attaatttaa cctttaaaaa
     8641 atctctaagt tctatataca cttcttgttc tttttcaaat ttaatttcaa gtttattggg
     8701 gtgtatattt acatctatac atgatgggtc tacttctata tttaagaagc acactgcatg
     8761 tttacctatt ggaattatag acttataact ttctgttatt gcatctatga ttattttact
     8821 ttttacaaat cttttattta tatagatatg ttgtaagttt ttatttgaac ggtatatatt
     8881 gttattacct atatatccat tcattttaaa gtgattgcac ttaaactcta catctattat
     8941 attttccgtt atttcttttc catatatact tctaatagtg tttacaagtt ttccatcccc
     9001 tggagtattt agcatctgtt tattgttatt tgtatattta aattgaatgt ttggattacc
     9061 tattgcaagt ttatttatca aatcacttat gtttatagtt tctgcatgag tagattttaa
     9121 aaatttctgt cttgctggtg tattaaagaa aatatctttt ataatgatgg tagttccatt
     9181 agtagaacct attggttctt tcgatattat ttttccacct tcaacatata ttttagttcc
     9241 tattatttca tctttagttt tagtcgtcat ttctaatttt gatacagctg aaatagatgc
     9301 caatgcttct cctctaaaac caagagagta taaatcatac aaatcatcaa tttttttaat
     9361 tttactagta gcatgtctca aaaatgattt ttcaacttca cttgaaggta ttcctattcc
     9421 attatctgta atcttaatta gactttttcc tccatcaatt atatctatgg aaattttatt
     9481 tgcacctgca tcaatggagt tttcaataag ttcttttact acagaagaag gtctttctac
     9541 aacttcacct gctgctatct tatttatagt caaatcatct aggatgttaa ttatattttt
     9601 catttttaca cctctaagat tttatttctt ttgcttttct ttgaagatta taaagagagt
     9661 ttatagcatc taatggagtc atatttaaaa tatccagatt taaaatttct tctgatagta
     9721 tatctctatt tacactatca aaagagattt gagttaaggc tacttctttt acagaatctt
     9781 cttgattaat tttctcttta tcatcatttt gcttcattaa agcaacttca tcatttaatg
     9841 ctttaaattt agaatttaat ttatcataat ccttttttat atgtttgtag tcttttacta
     9901 taagttcatg ttctattttt agagattcat atttattctt aaaattactt tgatttacct
     9961 taactaattc ttcgtccaaa ttactattaa ttatattatt gttttcttta tctccattta
    10021 ttgcaacact gttgtaaaca tgattttttt ccaagtcttt aagtatatat tttgctcttt
    10081 ctatgacttc gtctggtaat ttagctaatt tagcaacata tattccataa ctcttgtctg
    10141 ctccctgagg aattattttt cttaaaaata ttattccttc cccatcttct ttgactgcta
    10201 ttgaataatt tttaacctct ttaaactctt cttctaaatc agtaagttca tgataatgtg
    10261 ttgcaaataa tgtcttacat ctaatatttt tttgaatata ttccactatt gaccatgcta
    10321 aacttatacc atcataggta ctagttccac gacctatttc atctaatata actaaacttc
    10381 tctctgttgc attttttaat ataagggata cttcgttcat ctctaccata aaagtagatt
    10441 gaccttgaga taaatcgtca ctagctccaa ctcttgtaaa tattctatct aatattggaa
    10501 tatcagcaga ctctgctggt acaaatgagc ctatatgtgc cataagagct attatagcag
    10561 tttgcctcat atatgttgat ttacctgaca tattaggacc agttattatg ttaataatgt
    10621 tttctccacg atttaaataa gtatcatttg gaacgaaatt ttcctctcct actatatttt
    10681 cgacaacagg atgtctacca tttcttatat caagtttatt attttcattt attgctggtt
    10741 ttacgtagtt atttatatgt gcaactgttg caagggacac aaaaacatct atattagcta
    10801 tagtcttagc cactttttgt attctatcta tgtttttata tattgtatct cttatctcta
    10861 caaatatctc gtattctaaa gatttaatct tttcctctgc atgtagtatc ttttcttcta
    10921 tttcctttaa ttctggagtt atatatcttt ctgcattact aagtgtttgc tttcttatat
    10981 atgtctcatc tagctttgcc tgtttaaagt tggcttttgt tatttctata taatacccaa
    11041 aaactttatt aaatcctatt tttaatgatt taactcctgt tttttctctt tccctgtttt
    11101 ctatttcctt tacaagaaag gctccattct tagaaatctc tcttagttcc ttaagttcat
    11161 cactaaaatc tgatttaatt atgtttccat cttttatggt tatcgtaggt tcttctagaa
    11221 tagcttcatc tattaaattg tatatatcat ctaatttatc catttctgaa acatactctt
    11281 ttaggatttt tgcatttgat aaatttatag tatcttttaa attaggtaac ttttctatcg
    11341 aattttttaa gtgaattaac tcttttggtg ttactctctc aaatgctatc tttccacata
    11401 ttctttctat atcgtatata tttttaagta tatcatttag gtcttctctt aatataaagt
    11461 catcttttat ttcttctatt acatctaatc tattttcaat tttagattta tttatcaaag
    11521 gttcttctac atattttctt aaaagtctac ctcccattgc tgtagaagtt ttgtcaagta
    11581 catgtaataa tgaacctttt ttcttattcc ctcttatagt ttgagtaagt tctaaattag
    11641 ttctagtaaa catatctaga accatatatt ctgatgaatt gtatatattt atattattaa
    11701 tgttagatgt tatttgtttt tgagtattgt atatataatt cagaagaatt gataagcttg
    11761 actttattag acctttatca tcaaacttta gtttttgtag ataaacatct ggaaaatatt
    11821 cttttaatat atttatatcc aaatagttat cactaaaact ttcatttatg tatatattac
    11881 ttacagtagc tatatctcta agcttttcta taaagtctaa atcatttata attatttcag
    11941 ttggatggat ttttgcaatt tcttcaatta ccttatcttc atttaaacat gttgcattag
    12001 tttctcctgt acttatatca acataagtta gacctatatt agtaccatcc ttatacaaag
    12061 ataataaata attattcttt ttattttcaa gtaaatttcc atctaaaact gtaccaggag
    12121 tgatgaccct tataacctct cttctaacaa ttccttttgc tgtagatggg tcttccattt
    12181 gttcacctat tgctacttta tatccatttt caactaattt tgatatatat gaattggctg
    12241 agtggaaagg aacaccacac ataggagcac gttcttctaa accacaagct tttcctgtca
    12301 atgctatttc aagagctttt gaagctacta atgcatcttc aaaaaacatt tcataaaaat
    12361 ctccaagtct aaaaaacagt atacagtctt tatatctatt ttttacttca agatactgtt
    12421 tcatcatagg agttaattta ttcatatcta tttgcattat caaacctcct tcttttctaa
    12481 ttaaatatta tatcatagta gatgattatt attaacacaa tatataaaat tttgacatat
    12541 aactaaaaac aatccaaaat gtatactcac attttggatt gctaagttta atgcttatta
    12601 aataaaaata ttttttttta caataaagat attatttctt ttttaagttt aatgatattt
    12661 tcaaggttat cttcatttaa ctttctacta tctataacaa attctttctt tactattgat
    12721 ggtttttttg aaataacata aattctgttt gatagcatta tagcttcgtc aatatcatga
    12781 gttataagaa gtattgttga atttactttt ttcttaacat ctaaaagcca tttttgcatg
    12841 gatgttttag ttaatgaatc aagtgcccca aaaggctcat ctaaaagcat tatgtcatta
    12901 gaatttataa aagttctcaa gaagttagct ctctgtctca ttcctccaga aagttctgaa
    12961 ggatatttat cttcatatcc gcttaatcca aacacctcaa aataaggttt taccattgac
    13021 ctagctttac tctttttttc tttttttaaa attagtggta gtgacacatt atctattata
    13081 gttttatatg gcaagagtaa atctttttga tacatataac tatacttacc atttatattc
    13141 actttgccac tatcataatc tgtaagttta gttataatat taaaaatagt actttttcca
    13201 catccacttg gccctaatat agaaacaaac tcaccttcat aaacatcaat acttatatct
    13261 tttaaaactt caatatcttt ataagttttt gatacatttt ctatagatac ttttactttt
    13321 ttattgtggt aaaaattcat ttgtgtaagc atcacttgcc ttcatatcct tatctattaa
    13381 tttatattct tttaagaatg atgtatagtt gttccataca ctatctttca tttctcccca
    13441 tcgtggtgca tcatctttgt acttgcttgc taaatattct tgactcttta aagctagttt
    13501 ttcatctact tcaggtgcat gttttactaa aatttttgct gattcttctg gattttttat
    13561 tgcatattca taaccttttg ttgtagcttt taagaatttt ttagcaagct ctggattatt
    13621 tttaagcaca gtttcattag aaattataag tggtgtataa taatccaatc tctcatctaa
    13681 atcttttact ggtataaagt ttaagtcata tccaattaaa tcagctttaa ctgcatccca
    13741 accttcaaat atccatgcaa aatctacagt tttcatagct gcaaagaaat catcttgacc
    13801 agtattaact atctttaact tattaaaatc agctccattt ttcttcataa ctgctttaaa
    13861 aacagcttct tctgatggag agccccaacc accataagtt tttccttcaa aatctttagc
    13921 tgttgttata ttcttttctt ttggtgatgc aaacccagaa gtattatgtt gtataacagt
    13981 tgctacagct tttattggaa gtggatcttc actagtcttt gcataagtaa cttgttcttg
    14041 atagcttata ccaaagtcag cttttcctgt tgctactaaa gtttctgctc cactttcagg
    14101 tggttgtact atttcaacat ccaaaccttc ttctttatag taacccttat caagtgctac
    14161 aaataatcca gtatgatttg tatttggtgt ccaatcaagc accatagtta cttttttaga
    14221 agaagtatct ttatcattgt ttttgtcttt attgttattt gaagaacatc cagttattgt
    14281 tgccaatgta aaaacactta ctaaacctaa tattcctaac tttttaaaat tcataattgc
    14341 ctccctcaaa tacctttaat ctattaatct atgtcttata acaacttttt ttacagcctg
    14401 tacaattcct acaaacatta aactaaatat aactactaat atagtagatg caaatacttt
    14461 atcaagtgca tatgcacttt ttgacctaag catataaaca ccaagtcctt tcgttccacc
    14521 tagccattct gcaacagttg ctgccattac agcatacgtt gcagatattt taagtccaga
    14581 aaaaaattta tccattgcca taggaaattt aaggtgaatg aatgtattaa ctttatttga
    14641 gtccatagtc ttaaataaat ttaaataatc tttatcaata ttctcaatgc catctacaaa
    14701 acttattaat ataggaaaaa aacaagtaag cattaccatc aatacttttg gcattgttcc
    14761 aaatccaaac catatcataa agagtggtgc tataattatt gtaggtatca tctgtgtaac
    14821 caacataata ggataaagac atttttttat tattgataca aaatccatca atattccaat
    14881 taccaatgat attataattg cgactataaa accaagtatt gcttctccta tagtaaccac
    14941 agcatgtatg gataaatttt gataatcttt aaaaaacaca ttaattatat ctactggtgt
    15001 gggtagtata tactgaggaa cttctaaaac tcctaccata gattgccaaa gaataagtat
    15061 aaacaaaaat gttgctattg gatatatact atctttgact ttatctatga tttctaagtt
    15121 tttcatctat agtcagacct ccagcttttt catctactct agctactgtt atgactcttt
    15181 cacatccaag attaaaaggg attttatgta ccttttttaa taattcaaaa acttcatcaa
    15241 aatcaccttc aacagtagtg ctcattgctc ctatttcaca tttaagacca cttttttcaa
    15301 tttcagcaat acaagcatct actactttat acatctcttc ttcacctttg taaggtctta
    15361 gtggcattac tgctatgtct gcgattacca tttaaatcac tcctttaaaa ataattaata
    15421 cctactaggt atattttgtt ttttattaaa aaattttatt actaaaaaga tattatattt
    15481 aaataaaaga aaagtcttat ccaaaatagg ataagactta tttttatctt aactggtctc
    15541 cctacactgg cattatccaa acaggttcaa agggtcgaga taaaatctcc tctcagcaca
    15601 ttagctcccc gaaatatatt atatcttttc tacttgatta tactacactt atcatatttt
    15661 aacaaatttt ttatttatat tagatatttt atccgttcaa aaatatctaa tataaattgt
    15721 acattattac accaaataaa ttatcttaaa atggtaattt atcaacatct tccaaaacta
    15781 gattaactga attttctagt ttttattttg ctatttcaag catatttgga tgtatatcaa
    15841 ttccatacaa atattgtgct aaatttctgt tttcactcat ctaatttgca atcgttacaa
    15901 attacagatt agaaatagct tttagactct acttatcttt atctacaaaa aatccttcaa
    15961 taaattcatt aataatattc agtaatctaa aaataaacct ctatctagat ttttaagata
    16021 caagcctttt aggaagtatc ttttgtgata atataaaaat tactcatcat tatcatcaaa
    16081 atcctcagca accaacattt tagataagaa tcaaactcta taatataatt attttatcca
    16141 atttattttt gagaaataaa atattttttt aatttttaaa ttttttaata tgcaccttga
    16201 aaaaagaaac gttttcctat attatggtaa tagtagaata aaactaaata ggcaaaacta
    16261 gagaaattta gtgacgcaaa gctataggga ctaagactta tgaaatgagt tatgtcagcc
    16321 agttgccaaa gagatatttt ctttttgttt ttatgaatgt tttttagggg gatatatgat
    16381 atatgtttat ggataaaatg gatagatgta cacatatact aactgcatat atatgcagtt
    16441 cacgcgatta ctgcaatttt atagatacac aattaaatga ttttatacta gaatatggag
    16501 agaatgtggt agaatcttgt ttgcatcaag tgatggtatt ggtaagcaga tataattaaa
    16561 gaaattttat tttctagaaa acccttttta gttttatcta cgttttataa ttcattaaag
    16621 aactaattaa aataagcttc attatatatt tttcataaag taaacagttg agtttatctc
    16681 atatactgtt taccccaatt acataattct aataatatag attctaatga tttaccacgt
    16741 ttagtagaca aatattcaac ttttggagga atagtcggat aagaaatcct cttaataagt
    16801 ccatctcttt caagatactt taattcttgt gacagtatct tatgacttat atgaacaact
    16861 tcttttttta attgactgta acgtattggc tcttgtttta aaatatgcca taaaataatt
    16921 gccctccatt tacttcctat cacagtcatg gtaaaaccaa ttgaacaatt aaaatctttt
    16981 tgtctttctt caatatttgg aaattcttca aaattattat ctatatccat ctcaatcctc
    17041 tctttcaaaa tagtaagtat ctaactaaaa agtgcattct tgtttagcgt actaattcgt
    17101 aatataatct tgattgtagt atagagcctt acataatact acttttttag atgtatatgt
    17161 ttaaacttta atatagacat atgttatttt attaatttta tttaaacaga taataataaa
    17221 taataattta tctcaagttt tctatgtaga taaactaatc taatgtttag aaaggattat
    17281 ataatatgaa taaaaaattt cgtctttatc aagttgactc attacaaaag aaaaatttac
    17341 aggtaatcca gctggtgtaa ttacaaatgc tgatggctta tctgaatcac aaatgcaaaa
    17401 aatagcaaga gaattaaata attcagaaac tgcttttatt ttcaataact tggctaaaaa
    17461 tcatcaagaa aattatgatg tacatatcag attttttaca ctaactaatg aggttcctat
    17521 atgtggtcat gctactattg ctgcccatta tgttagagca gtagaaaacc aattcaataa
    17581 caaaacagta tttcaaaaaa ctagtgctgg aatattacca gttgatatta taaaaaaaga
    17641 taatgattat gaaataatta tgacacaagg aaaaattgaa gtatctccac cgttacaaca
    17701 aacctatcaa aaaagattac ttaatgcatt tggtatttta aaggaagata ttcgtacaga
    17761 ttgtcctatt gccatatcat ctacaggaca ttcaaaagtt atgattggaa taaaggaatt
    17821 atcaacatta aatagtttat ctccaaattt atatgaatta tcgaaaataa gtcaagaaat
    17881 aaaatgtaat ggatattata tttttacatt acataataaa gaaactctac aagttcatgg
    17941 aagaatgttt gctcctgcaa ttggtatttc agaagaccct gttacaggaa atgctaatgg
    18001 acccttaggt gcgtaccttg tacattataa agtaatacct acacccaaca cagagtttat
    18061 atttgaagca gttcaaggag aaacaataaa acgcaaaggc aagatgttag taaaagtaat
    18121 tattttagat aataaaccag ttgaagtaaa aataattgga aaagctgtaa ttgcattctc
    18181 aacaaacata gaaatctaat tatagattcc ttctaagtaa atttttgaac tttttaatac
    18241 taatt
//
LOCUS       DAJMZY010000085        16766 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.085, whole genome shotgun sequence.
ACCESSION   DAJMZY010000085 DAJMZY010000000
VERSION     DAJMZY010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16766)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16766)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16766
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.085"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            102..3005
                     /locus_tag="OE968_002754"
     CDS             102..3005
                     /locus_tag="OE968_002754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HCP7220023.1"
                     /translation="MELRDKLVNIINTENKKDPLTDVQIAKFLSTTRENITNLRKELN
                     ISNSRQRRYPYLKSAISAILQKNKNISVSEITRELMTEGFNISRRVVEELLPKESLEM
                     DVVEESEEESNDPFETLIGNKGSLRNAVEQAKSAILYPPKGLPTLIIGESGVGKSLFS
                     RHMYEFAKQKKIVKESSNFVVFNCADYSDNPQLLLSLLFGYKKGAFTGAEYDTPGLVE
                     EADEGVLFLDEIHRLPPKGQEILFSILDRGKFRRLGETNAERKVSIMLIGATTENVET
                     NLLLTFRRRIPMLITLPPLHDRLLKEKIDLIYNIFQQECNRINAKIFVDKNVIEILAL
                     KKFSGNIGQLQNMIQVLCARAFMKFINSKDEDSESIVVVDINEVLKLKDSFKDAAFQE
                     IEYTEIRKYLKNAIFIPFNLEESSVKGSLLSDEYILPEDIYKTIEKKYYDLKSLDIED
                     IDIENILWTFILNRFADLKFNLDSNEEIFSMSDLNSFVSDSLVKLVKELMNDIVEKNM
                     NLEVNKNMFKYLAIHLEEAIKRIKLNQKIINVNLEKIKIDFSKEYEISKSFAIKIEES
                     IGIKIPDDEIGFITLYIKSALKNEVKKDKVGLIIISHGRIATETVNVVKELLGVKFPV
                     AIDMPLDEKPINIYNKAVELSKIIDQGKGILFLVDIGSLTNIGQIVNKRTNISTKTID
                     RVDLLMALEATRKVSMGEEELDEIFFSLLKDRMGYNYELEKHIDKSNAIVTLCLTGEG
                     TAKYISKTLEEKYDNTKCYQMSALDENLFCKIENLKETNNILAIVGTINPKIPGINFI
                     PYNKELFKNLDIYLSKSKQQDDRPVKSYERMLDEDLVIFEPDIYFKKDLLEYVCSILI
                     NKEYVEKDYLDSVLHREEMLPTYSKGAIGVPHGDSSTVNSTRFVFVKLKNPIDWGVGN
                     VNFIFMPVFQANDKEIVKNVLEILKDAEFMNNANKCFDKDAFRRIIFDKFKHL"
     gene            3038..3484
                     /locus_tag="OE968_002755"
     CDS             3038..3484
                     /locus_tag="OE968_002755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HCP7220024.1"
                     /translation="MNVDLISLGLESNDYESVIEELGSIMCKKEYVKETYINAVLERE
                     RTLPTGLDIGEMCVAIPHTDSKHVNESNVAVGILKNPVKFNSMIDPKDRLDVELVFLL
                     AVKNPDSQVKLLKDLMSVFQNIKLLKNIKNASTKEEVAKLLDFIEI"
     gene            3607..3909
                     /locus_tag="OE968_002756"
     CDS             3607..3909
                     /locus_tag="OE968_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCP7220025.1"
                     /translation="MKQFNVLSVCGSGTVTSSMVAGKLKEVLGNKGISITTTEARPTE
                     ALNLAQSGRFDFITFTSPLQTGDYGIPTINAFACLTGIGEEAFFEEVLTVIEGIDK"
     gene            4090..5496
                     /locus_tag="OE968_002757"
     CDS             4090..5496
                     /locus_tag="OE968_002757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HCP7220026.1"
                     /translation="MLEFMKSIIDTFGSAIIVPIIIFIIAKIFKVTTKKSFLSAVYAG
                     VALQGFTLILNSFTPIITPVINRMVESTGVNLPVFDVGWQATSLVAFSTSAGMIYLGL
                     GILLQTILFLIKWTDVFQPSDLWNNYSYMVWGAMVIGVTGNFPLGIACMVLLNLYSLL
                     ISELVAKRWSSYYRYPNCTIIAMHNVEASVFAVFADPIYNKLGLNKIKLNPKELEKKL
                     GFLGEPITLGLFLGMFIGILGNMTRINTMEAWGEIMKVGISTSAVMAIFPKVASMFAQ
                     AFAPITEAARKIMQKAGNREWYIAVNDAVGYGEPATLISGLILIPIMLVIAMVLPGNK
                     VLPVVDLLAIPYMVQGLVAIHNGNIPKVLVSGIIWFGLGLYVCTSTAPLFTDMATNIG
                     VAIPAGAMLITSFNILGKPLMGLVFFAFLSANPIYIGLSVVIYFVLWALFRKNKTSIL
                     DYLEKQALKNVEEEPVAV"
     gene            5840..6898
                     /locus_tag="OE968_002758"
     CDS             5840..6898
                     /locus_tag="OE968_002758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012101107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HCP7220027.1"
                     /translation="MGDKMRASVLYSVGDVRYEMVDIPEITDTQVLVNVKYVGICGSD
                     LPRSMVSGLSGNTKYPLILGHEFSGEVVKIGEKVKHINVGDRVAVAPLVPCGKCDYCN
                     EGNFGLCDDYNIIGTRVNGAFAEYVRVPEEHILKLPDTLDYETAAGIEPATIAYHGIS
                     KSNIRVGDSVVVLGCGPIGQFVIQWAKVFGASKIIAVDIFDEKLELSKLLGANYILNS
                     KEVNVIKEIKKITNGGADVVIETAGSRFTQEQSLFVAKKRGNIVFVGISHTELPLSAD
                     ATECILRGELTLKGSWNSYTSPYPGRAWTATLDFMGKGDIIFKPMISHKIGLNEVGDF
                     LSKMSKREINFNKILVEI"
     gene            6997..7683
                     /gene="araD"
                     /locus_tag="OE968_002759"
     CDS             6997..7683
                     /gene="araD"
                     /locus_tag="OE968_002759"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HCP7220028.1"
                     /translation="MLENLKEEVLKANLELPKKKLITYTWGNVSGIDREKGLVVIKPS
                     GVEYSNMTVEDMVVVDLEGNIVDGKLRPSSDTPTHLVLYKEFEELGGIVHTHSSWATI
                     WAQIGKSIPSCGTTHADYFYGSIPCTRKMTREEICNEYEKETGNVIIEEFMGRNPIHC
                     PGIIVNDHGPFTWGKDANEAVHNAVVLEEVAKMAYYTELMSPDNIMDKVLMNKHFSRK
                     HGKNAYYGQK"
     gene            7701..8348
                     /locus_tag="OE968_002760"
     CDS             7701..8348
                     /locus_tag="OE968_002760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HCP7220029.1"
                     /translation="MLDSLKGKIVEIAIKAEHYGLCKEKTGNFSIRDKDTGYILITPS
                     GVGREELKVEHICVLDLDGNVIEVEKGIKPSSEVLMHIEIYKTRENINAISHTHSLYA
                     TAFSVAKKPIIPIVYESVNYGGYVDIAPYERPGTLKLAKSVSKLLIDTDACLLERHGL
                     TTVGNDLDEALLKSRYVEEVAEIYYRSLVLNQFKELEVVDVDEFKSWKYPEEIKF"
     gene            complement(8521..9888)
                     /locus_tag="OE968_002761"
     CDS             complement(8521..9888)
                     /locus_tag="OE968_002761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HCP7220030.1"
                     /translation="MNLIDILNKVDAFIWGPPLLVLLVGTGILLTVKLGVVQITKLPR
                     ALKLIFSAENKGSGDVSSFAALCTALAATVGTGNIVGVATAIKAGGPGALFWMWIAAF
                     FGMATKYSEGVLAIKYRTKDKNGQVSGGPMYYIVNGMGEKWRPLAIFFAISGILVALL
                     GIGTFTQVNSITDAINNSFGIDPRITGVVLAVFVALVVFGGLKSISNVATKIVPFMAV
                     IYVVICGIILISFWNKIPETFMLIIKSAFTPTAATGGFLGATMSLAIRNGIARGVFSN
                     ESGLGSAPIAAAAAKTEWPAEQGLISMTGTFIDTIIICTLTGFSLVISGVWCSDLNGA
                     VMTQAAFNGAIPTFGPILLTVSLTLFAFTTILGWSYYGERCFEFLFGVKGMNGYRTVF
                     VAMVLLGAFLKLEVVWIIADIVNGLMAIPNLIALLALSPIIVSETKKYFEHINSPENQ
                     IKKNA"
     regulatory      complement(10078..10166)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            10594..12714
                     /locus_tag="OE968_002762"
     CDS             10594..12714
                     /locus_tag="OE968_002762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HCP7220031.1"
                     /translation="MGKILVLAEKPSVGRDIAKVLGSKNEKNGYIEGPKYVITWALGH
                     LVTLADPESYGERYKSWSLEDLPILPKHLKTVVIKKSGKQFNTVKSQMNRNDIDEIVI
                     ATDAGREGELVARWIIEKSQVKKTIKRLWISSSTDKAIKDGFAKLRSGKEYENLYYSA
                     IARAEADWIIGINATRALTTKYNAQLSCGRVQTPTLAMLLKREEEIRNFKPKEYYGLE
                     LIATKGNSDIKFIWNDKNNNSSTFSKEKIESTLKKVKGVDIKISEVNKSYKKKYSPAL
                     YDLTELQRDANKMFGFSAKETLSIMQKLYEHHKVLTYPRTDSRYLTSDIVGTLKDRIK
                     AVNISDYSKTCNKLLKSNIIANKSFVDNSKVTDHHAIIPTEQKVFMSDFSDKERKIYN
                     LVVKRFLAVLSPPFEYEQTTISATVEGEIFKAKGNKVINLGWKESYKDIEDEDEYESI
                     PNILEKDVLKVKGLKITSGKTNPPPYLNEGTLLTAMEKNGLGTVATRADIIEKLFNSF
                     LMEKKNKDIYITSKGRQLLDLVPVDLKTPELTASWEKKLLDISKGKLSKNTFINDMKD
                     YSKDIVLEVKNSDNKFKHDNLTKNRCPECGKFMLEVNGKKGKMLICEDRECNTRKTIS
                     QVTNSRCPNCHKKLELRGEGEGRIFTCSCGYREKLSSFNKRKQEEKQKASKKDVNQYL
                     KNQNKNQETFNNPFAEALAKLKNK"
     gene            12818..14071
                     /locus_tag="OE968_002763"
     CDS             12818..14071
                     /locus_tag="OE968_002763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein FliS"
                     /protein_id="HCP7220032.1"
                     /translation="MDLSGIFKYYCKECENTWNNSSVELFENIETYSKDSQKKREKEL
                     DKLLNTISVHLERYPSDAVLRKMWVKKGEVFLQKTLEKENIFKLEKMDVEDRKKFLDI
                     TKQFIRDARKFDDDLPIGDIMQAMRNVWISNALQLLFGKEVYYSKANFAYSMLYPYTD
                     NYLDNTNIDKNDKILFNNWLEKRLLGEHIKSKDYHESKVSKMIDYIESVYPREKFTEV
                     YESLLLIFKSQVNSLKQHGKENHLCKEDLLSISIEKGGSSVLVDGYLISGLMTKEEIE
                     FCIGYGFLLQISDDLQDIKEDLKYNHKTIITEMSKEGTLDKVVNKLINFTIELIDSFK
                     INNKNKSVITMIKNDCLMLILFSVVYNAEFFSVGYIKEVEKFIPYTIDYSLEIEEKIK
                     EKFKNIDVLNNENEYKEMIDIICAE"
     gene            complement(14224..15285)
                     /gene="ytvI"
                     /locus_tag="OE968_002764"
     CDS             complement(14224..15285)
                     /gene="ytvI"
                     /locus_tag="OE968_002764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation integral membrane protein YtvI"
                     /protein_id="HCP7220033.1"
                     /translation="MDIQKQKNFIIKFTYVVLITSIVYIVLKFLLPLLMPFVISFIIA
                     SILRPIIRLITNNTNLNRTLISIVILLIFYGLCIFLLVSFGVKIFASVSDVFFRLPEI
                     YKSSIQPTLNTLFSKIDASTPNVNLALILGWDNISQSMMSLVASISTNALNAIASIAS
                     KTPAFMLKLIITLIASFFFTFDYQKIVNFILKQFPEKSQFMIINIKNSSINALLKLLK
                     AYAILLSVTFIELLIGLTILKVENAFTISVIIALVDILPVLGTGSILTPWMIISLING
                     NINLAIGLLILYIIITVVRQILEPKVVGHQIGLYPLITLMCMFVGAQLFGIAGLFGFP
                     IAATIIKNLHDNGIITAFK"
     gene            15559..16299
                     /locus_tag="OE968_002765"
     CDS             15559..16299
                     /locus_tag="OE968_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein phosphatase"
                     /protein_id="HCP7220034.1"
                     /translation="MKNFRDLGGNKTEDGRTVKKGLFYRSAKLSNLSENDIKILKELN
                     IKYIFDYRSDEEARKHPSTIISNIKNIRIPAMRELEESGGSFGSIEDMIDGLFEKDGA
                     FNMLNNSYYNLPINNPSYKKLVELIRDYSNLPILNHCTAGKDRTGVGSAIILMILGVS
                     RENIMKDYLKSNDFADKEIERFIEYKPKFKDIPKENLKYIFGVNEEYMKTAFRRIDEE
                     YISVEAYLYGEFNLNKEEIRKLRNQYLE"
     gene            16311..>16766
                     /locus_tag="OE968_002766"
     CDS             16311..>16766
                     /locus_tag="OE968_002766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HCP7220035.1"
                     /translation="MSLNITARQINIIKILLNSKDTISGIALSQEIGCSSKTIQNEIK
                     DINKQLRNGKILSIRGVGYKLEGSFDEVNLNSNLYDDVDRVEYIIRKILTLSNEEKNT
                     IKLEDLADSMYVSVSTVKNDLKEVKRMLEKYSISVKSKHKQGICVLESED"
BASE COUNT         6722 a         1851 c         2901 g         5292 t
ORIGIN      
        1 tatgacatct agttacttac agggtttaag tagaaaaaaa tatcaaagta agtatggcat
       61 gatagttgct tatatattta tcaagaaagg agttattaag catggagttg agagataaac
      121 ttgtaaacat cataaataca gaaaataaaa aagatccatt aacagatgtt caaatagcaa
      181 agtttttaag tacaactaga gagaacataa ctaatttgag aaaagaactt aatataagta
      241 attcaaggca aagaagatat ccttatttaa aatcagcaat ttcggcaata ttacaaaaga
      301 ataagaatat ttctgtatca gaaattacaa gggaattgat gacagaaggc tttaatatat
      361 ctagaagagt tgtggaggaa cttttaccta aagaaagttt agaaatggat gtagtagagg
      421 aatctgaaga agaatcgaat gacccatttg aaactctgat aggtaataaa gggagtctta
      481 gaaatgctgt agagcaggct aaatctgcta tattgtatcc accaaaaggg ttaccaacgt
      541 tgattattgg ggaaagtgga gttggtaaga gtttattttc tagacatatg tatgagtttg
      601 caaagcaaaa aaagatagta aaagaaagct ccaattttgt tgtatttaac tgtgctgatt
      661 atagtgacaa tccacaatta ttattatctt tgttatttgg atataaaaaa ggtgcattta
      721 caggtgctga atatgataca ccaggtcttg tagaagaagc tgatgaagga gttttatttt
      781 tggatgaaat acatagattg cctccaaaag gccaagaaat actattttct attttagata
      841 ggggaaagtt taggagatta ggtgaaacta atgctgaaag aaaagtaagt attatgttga
      901 ttggggcaac tactgaaaat gtagagacta atttattatt aacattcaga agaaggatac
      961 caatgctaat aactttgcca ccattacatg atagattact aaaagagaaa atagacctta
     1021 tatacaatat ctttcaacaa gagtgtaata gaataaatgc aaaaatattt gtagataaaa
     1081 atgtgattga aatacttgca ctaaaaaagt ttagtggaaa tataggacaa ttacaaaata
     1141 tgattcaggt tctttgtgca agagctttta tgaagtttat aaattccaaa gatgaagata
     1201 gtgaatcgat agtagtagta gatataaatg aagttttaaa gcttaaagat tcttttaaag
     1261 atgctgcctt tcaagagatt gaatatacag agataagaaa atatttgaaa aatgctatat
     1321 ttataccatt taatttagaa gaatcatcag taaaaggaag tcttttaagt gatgaatata
     1381 tattaccaga ggacatatac aaaacaattg aaaagaaata ttatgaccta aaatccctag
     1441 acattgaaga tatagatata gagaatattt tatggacttt tattttaaat agatttgctg
     1501 acttaaagtt taatctcgat agtaatgaag aaattttttc aatgagtgat ttaaatagtt
     1561 ttgtaagtga tagtttagtt aaactggtaa aagaacttat gaatgatata gttgaaaaaa
     1621 atatgaattt agaagtaaat aaaaatatgt tcaaatatct agcaatacac ttagaagaag
     1681 ctataaaaag aattaagcta aatcaaaaga taataaatgt aaatttagaa aaaataaaga
     1741 ttgacttttc aaaagaatat gaaattagta aaagttttgc aataaaaatt gaggaatcaa
     1801 ttggtattaa gattccagat gatgaaattg gatttataac actctacata aagtctgctc
     1861 taaaaaatga agtgaaaaaa gataaagtag ggttaataat aatttctcat ggacgtatag
     1921 ctacagagac tgtaaatgta gttaaagaac ttttaggtgt aaagtttcct gtggctatag
     1981 atatgccttt agatgaaaaa ccaataaata tatacaataa ggcagtagaa ctgtcaaaaa
     2041 taatagacca agggaaaggc atattgtttt tggtggatat tggttcactt acaaacatag
     2101 gtcaaatagt aaataagaga accaatataa gcactaaaac tattgataga gtagacctcc
     2161 taatggcact agaagcaact agaaaagttt ctatgggaga ggaagaactt gatgaaatat
     2221 ttttttcttt gctaaaagat aggatgggat ataactatga attagaaaaa cacatagata
     2281 aatcaaatgc aattgtaaca ttatgtctta ctggagaagg aactgctaag tatataagta
     2341 aaacgttgga agaaaagtat gataacacta aatgttatca aatgagtgca ttggatgaaa
     2401 atttattttg taaaattgaa aatctaaaag agacaaacaa tatattagct attgttggga
     2461 caataaaccc taagatacca ggtataaatt ttatacccta taataaagaa cttttcaaaa
     2521 atttggatat ctatctatca aaatcaaaac aacaagatga cagaccagtt aaatcgtatg
     2581 aaagaatgct tgatgaggat ttagtgattt ttgaaccaga tatatatttt aaaaaggatt
     2641 tattagaata tgtatgttca attcttataa ataaagaata tgtagaaaaa gattacttag
     2701 attctgtttt acatagagaa gaaatgcttc caacatattc taaaggagct ataggtgtgc
     2761 ctcatggaga ttcttctact gtaaatagta caaggtttgt ttttgttaaa ctaaagaatc
     2821 ctattgattg gggtgtaggt aatgtaaatt tcatatttat gccagttttt caggctaatg
     2881 ataaagagat tgttaaaaat gttcttgaga tactaaaaga tgcagaattt atgaacaatg
     2941 ccaataagtg ttttgataaa gatgctttta gaaggattat atttgataaa tttaaacatc
     3001 tgtagccata gcaaaaaaat tgagaggagt tagagtaatg aatgtagatt taatatcatt
     3061 gggtttagaa tctaatgatt atgaaagtgt tattgaagaa ttaggaagta taatgtgtaa
     3121 aaaagaatat gtaaaagaaa catacataaa tgctgtcttg gaaagagaaa ggacattacc
     3181 aacaggtcta gatattggag aaatgtgtgt tgctattcca catacagatt caaagcatgt
     3241 aaatgagtct aatgtagctg tagggatatt gaaaaatcct gtaaagttta attcaatgat
     3301 agacccaaaa gatagacttg atgtagaact tgtattttta ttagcagtaa agaacccaga
     3361 ttcacaagta aaactgttaa aggatttaat gtcagttttt caaaatataa agttattaaa
     3421 aaatataaaa aacgcatcaa caaaagaaga agtagctaaa ttattggatt ttatagaaat
     3481 ttaatgtagg agaattttat aaataaaaaa ttaaaattta aacaatcaaa gtaagtatta
     3541 tttttttaat aggtttaatc ttatataaaa taaaaattta gagtgaaaaa ttaggaggaa
     3601 attattatga aacaatttaa tgtattatca gtttgtggtt cagggacagt tacatcatct
     3661 atggtagcag gtaaattaaa agaagtacta ggtaataagg ggatttctat tactacaaca
     3721 gaagctagac caacagaagc actaaattta gcacaatcag gaagatttga ctttataaca
     3781 tttacgagtc cacttcaaac aggcgattat ggaataccaa ctataaatgc atttgcttgc
     3841 ctaactggta taggggaaga ggcattcttt gaagaagttt tgactgttat tgaagggata
     3901 gataagtaag ttttggagac gtgaatttat agtatttaaa tcaatgattt agatactata
     3961 ataagctaat attaactaaa tatttgtgga aaaaacattt tatatgttgt cataaattaa
     4021 aaaattataa aaatagtcac ttaagtatta aattaagctt ataaatattt ataagtagga
     4081 gggaaaaaga tgttagaatt tatgaaatct ataatcgata catttggttc tgcaattata
     4141 gttccaatta taatattcat aatagcaaag atatttaaag taactactaa gaaatcgttt
     4201 ctttctgctg tgtatgcagg agttgcttta caaggtttta cactgatttt aaattcattt
     4261 acaccaataa taacaccagt tatcaatagg atggttgaga gtacaggagt aaacctacca
     4321 gtttttgatg ttggttggca agcaacatca ttggttgcat tttcaacaag tgcaggtatg
     4381 atatatttag gtcttggtat attattacaa acaattttat ttttgataaa atggacagac
     4441 gtgtttcaac catcagattt atggaataac tattcttata tggtatgggg agcaatggtt
     4501 ataggagtaa caggaaattt tcctttaggt atagcatgta tggttttatt aaacctatat
     4561 agtttattaa tatcagagtt agttgcaaag agatggtcta gttactatag atatcctaat
     4621 tgtacaataa tagctatgca taatgttgaa gcttctgtgt ttgcagtatt tgcagaccct
     4681 atatacaata aattgggatt aaataaaata aaattaaatc caaaagaatt agagaagaaa
     4741 ttagggtttt taggtgaacc aattacttta ggtctttttt taggtatgtt tataggtata
     4801 ttaggtaata tgacgagaat aaatactatg gaagcttggg gagaaataat gaaagtaggt
     4861 atatctacaa gtgcagtgat ggcaattttc cctaaagtag caagtatgtt tgctcaagca
     4921 tttgcaccta taacagaagc agctagaaag attatgcaaa aagctggaaa ccgtgagtgg
     4981 tacatagcag taaatgatgc tgttgggtat ggtgaacctg caactttaat atcaggtctt
     5041 atattaattc caataatgct tgtaatagct atggtacttc ctggtaataa ggtattacca
     5101 gttgtggatt tattggcaat tccatatatg gttcaaggtt tagttgccat acataatggt
     5161 aatataccaa aagtattggt ttcaggtata atttggtttg gattaggatt atatgtttgt
     5221 acatctacag caccattatt tacagatatg gctacaaata taggtgtagc tatacctgca
     5281 ggagcaatgt taataacaag ctttaatata ctaggaaaac ctttgatggg attagttttc
     5341 tttgcatttc taagtgcaaa tccaatttat ataggtcttt cagttgtaat ttactttgtt
     5401 ctatgggcat tgtttagaaa gaacaaaaca agtattcttg attatttaga aaaacaagca
     5461 cttaaaaatg tagaagaaga gcctgtagca gtttaagttt ataaaaatga aataagaata
     5521 attaaaggag tttataattg attttatata agtatcagat aatacctgag aaatatttaa
     5581 atgaaatata gacttctttt tatttgataa tatttgtaat tataatgcat tgtatcttta
     5641 tagttgagtt ttctgtataa cctgctattt aaaacatact cttttatatt tatacagtaa
     5701 tgtggtttaa ttttataaaa tgtaatctct actggtaaaa gactttgtat ataaggcatt
     5761 tgcctgaata aaccatttat cttttgtatg gcatagatat tgctatatag aagtatatag
     5821 catgaaagga gatatttata tgggagataa aatgagagca tcagtattgt atagtgtagg
     5881 tgatgtcaga tatgaaatgg tagatatacc agaaataaca gatacgcaag tgcttgtaaa
     5941 tgtaaaatat gttgggatat gtggttcaga tttacctagg tctatggtaa gtggtttgag
     6001 tggaaataca aaatatccat tgattttagg acatgaattt tctggcgaag ttgttaaaat
     6061 tggagaaaaa gtaaagcata ttaatgtagg agatagagta gctgttgcac cattagtacc
     6121 ttgtggaaaa tgtgattatt gtaatgaagg taattttggc ttgtgtgatg attacaatat
     6181 aattggaaca agagtaaatg gagcgtttgc agaatatgta agagttccag aagaacatat
     6241 tttaaaacta ccagatacat tggattatga aactgctgcc ggaattgaac cagcaactat
     6301 agcttatcat gggatttcaa agtctaatat tagagtagga gatagtgtag ttgtgttagg
     6361 atgtggtcca ataggtcagt ttgttataca atgggcaaag gtgtttggtg catctaagat
     6421 tatagcagtt gatatttttg atgaaaaatt agaactttct aaacttctag gagcaaacta
     6481 tatacttaac tcaaaagaag taaatgtaat caaagaaata aaaaaaataa caaatggtgg
     6541 tgctgatgtt gtaatagaga ctgctggtag ccgatttaca caagaacaat ctctatttgt
     6601 agcaaaaaag aggggaaata tagtgtttgt aggtatatca cacacagaat taccacttag
     6661 tgcagacgct actgagtgta tattacgtgg agaacttacc ttgaaaggtt cttggaattc
     6721 atatacaagc ccttatcctg gaagagcatg gactgcaaca ttggatttta tgggaaaagg
     6781 tgacattatt tttaaaccca tgatttcaca taaaataggt cttaatgaag tgggtgactt
     6841 tttaagtaaa atgagcaaga gagaaattaa tttcaataaa atcctagtag aaatataaaa
     6901 atttaataaa aaattctaaa agcaattaaa ttttataact atgacattaa ataaaataaa
     6961 aataattttc ttaaataaaa tataggagga agaaaagtgt tagaaaattt aaaagaagaa
     7021 gtattaaaag caaacttaga attacctaag aaaaagctaa ttacttatac ttggggaaat
     7081 gtaagtggaa tagatagaga aaaaggatta gtggtgataa agccaagtgg tgtagagtat
     7141 agtaatatga ctgtagaaga tatggttgta gttgatttag agggaaatat agttgatggc
     7201 aaattaagac cttcttcaga taccccgact catctagttt tatataaaga gtttgaagaa
     7261 ttggggggaa tagtacatac acattcaagt tgggcaacaa tttgggctca aataggaaaa
     7321 tctataccat cttgtggtac tactcatgca gattattttt atggaagtat accatgtacc
     7381 agaaaaatga ctagagaaga aatttgcaat gaatacgaaa aggaaactgg aaatgtaatc
     7441 attgaagaat ttatgggaag aaatccaatt cattgtccag gaataattgt aaatgaccac
     7501 ggacctttta catggggaaa agatgcaaat gaggctgtac acaatgcagt agttttagaa
     7561 gaagtcgcaa agatggctta ttatacagag ttaatgagtc ctgataatat tatggataag
     7621 gttcttatga ataagcattt ttcaagaaaa catggaaaaa atgcatacta tggtcaaaaa
     7681 tgattatctg gaggtgaatt atgctagact ctttaaaagg taaaattgtg gaaatagcaa
     7741 ttaaagcaga gcattatggt ttatgtaaag aaaagactgg taattttagt attagagata
     7801 aggatactgg atatatactt ataaccccat caggtgtagg aagagaagaa ttaaaagttg
     7861 aacatatttg tgtattggat ttggatggaa atgtaataga agttgagaaa ggtattaagc
     7921 caagtagtga ggtattgatg catattgaaa tatacaaaac aagagaaaat ataaatgcca
     7981 tatcacatac tcattcttta tatgcaacag cattttcagt agcaaagaaa ccaattatac
     8041 caattgtata tgaatcagtt aattatggcg gttatgtaga tattgctcca tatgaaagac
     8101 caggaacttt aaaattagct aagagtgttt caaaattact gatagataca gatgcatgct
     8161 tattagaaag acatgggttg acaactgtag gtaatgattt agacgaagca ttattaaaat
     8221 caagatatgt ggaagaggta gcagaaatat actataggtc tttagtatta aatcaattta
     8281 aagaacttga agtagtagat gttgatgagt ttaaatcttg gaaataccca gaagaaataa
     8341 agttttaatc taaataattt tcattgaagt ggttaattaa aatatatgta ttatttatat
     8401 caattactat gttttattat gttaattacc gtattttgca aatatattta ttacattttt
     8461 tcaaaaaaat atagaatccg aaagccatat aaaattgact tgggattcta tactttttat
     8521 ttatgcattt ttctttatct gattttctgg agaatttata tgttcaaaat attttttagt
     8581 ttcagatact attataggtg ataatgcaag taaagctata aggttaggta ttgccataag
     8641 cccatttaca atatcagcaa ttatccaaac aacttctaac tttaagaaag cacctaataa
     8701 caccatagcc acaaatacag ttctataccc attcatgcct tttacaccaa acagaaattc
     8761 aaaacatctt tctccataat aactccatcc caaaattgta gtaaatgcaa ataatgttaa
     8821 actaactgta agtaatattg gtccaaatgt aggaattgct ccgttaaaag ctgcttgtgt
     8881 cataacagct ccatttaggt ctgaacacca cactcctgaa ataacaagag agaatccagt
     8941 aagagtacag attataatag tatctataaa agtacctgtc atagatataa gaccttgttc
     9001 cgctggccat tcagttttag cagcagcagc agctattgga gcactaccta gaccagactc
     9061 atttgaaaat acaccacgag cgataccatt tctaattgcc agtgacatag ttgctcctaa
     9121 aaaaccacca gtagcagcag taggtgtaaa tgcactttta attattaaca taaaagtttc
     9181 agggatttta ttccaaaaag atattaaaat gattccacag attacaacat atataactgc
     9241 cataaaaggt actattttag tagctacatt agatatactt ttaagtcctc caaatacaac
     9301 caaagctaca aatactgcta atacaacccc tgtaattcta gggtctatcc cgaaactatt
     9361 atttattgca tctgttattg aatttacttg agtaaaagta ccgattccta aaagtgcaac
     9421 tagtatacca cttatagcga aaaatattgc aagaggtctc catttttctc ccataccatt
     9481 tactatgtaa tacattggcc caccagacac ttggccattt ttatctttag ttctgtattt
     9541 tattgcaaga acaccttctg aatacttagt agccattcca aagaatgctg ctatccacat
     9601 ccaaaaaagt gcaccaggtc caccagcttt gatagctgta gcaacaccaa caatattacc
     9661 agtaccaact gtagcagcta gagcagtaca taaggctgca aaacttgaaa catcaccact
     9721 acctttgttt tcagcagaga atattaactt aagagctctt ggcagtttag ttatttgaac
     9781 aactccaagc ttaacagtaa gtagtatacc agtaccaact aatagtacca gtaggggtgg
     9841 tccccaaata aaagcatcaa ctttgtttaa aatatcaatt agattcataa aaacactccc
     9901 tcattttttt tgctttacat aatcaataga atttttaatg aagtaattga caggaaataa
     9961 gtataattta ttaataattt ctagtgtaat aaaaaaagct aaatctaaaa aagattcagc
    10021 tctggatgta cactaattag caaccaaaat aaaagtatta gtaaatactg tttttggtag
    10081 ataatccctg tccttttgcc tgagagattg agcataaaag ccttgcccct tcggcgccca
    10141 taatgggtct ctccagagtt ccgtaaattt tacagtccta cttttaaaag tacctgagag
    10201 tgttactcct tcggtgtgct atatagcaac tcttctataa aatcttaacc ggatattgat
    10261 ttgtcatagc ttattgtatt aataatatta atataagttt ttatgttttg tcaactaaaa
    10321 aattaaaaaa caaagaaaaa atataaaaat gtaagcctat ttacgaatta taaacttaga
    10381 aagatgagta atatacgtga aaatgaattt tgtaatacac atacaaatga agtgtaaaat
    10441 aagttctaaa taaaaaaata ataaaatctt aaataattaa ttagatatga ttaaattatg
    10501 gtaatattat agttacgata ttaagaaaag ttctatttag ttagatttta agcgtaatat
    10561 gagattatgt atagagaaag gatgtatttt tagatgggaa aaatattagt gctagcagaa
    10621 aaaccttctg ttggaagaga tatagcaaaa gttttagggt caaaaaatga aaaaaatggt
    10681 tatatagagg ggccaaagta tgtgataact tgggcactag gtcatttggt tacacttgct
    10741 gaccccgaaa gttatggaga aagatataaa tcatggagct tagaagacct gccaatactt
    10801 cccaagcacc ttaagactgt tgtaataaaa aagagtggaa agcagtttaa tacagttaaa
    10861 tcgcaaatga atagaaatga tatagatgaa atagttatag caacagatgc aggtcgtgaa
    10921 ggagaacttg tagcaaggtg gataatagaa aaatcacagg taaaaaaaac tataaaacgt
    10981 ctttggattt cttcaagtac agacaaagca ataaaagacg gatttgcaaa attaagaagt
    11041 ggaaaagaat atgaaaattt gtattactca gcaatagcac gagcagaagc tgattggatt
    11101 attggaataa atgcaaccag agctttgaca acaaagtaca atgcacagct ttcttgtgga
    11161 agagtacaaa ctcctactct tgcaatgttg cttaaaagag aagaagaaat aagaaatttc
    11221 aaacctaaag agtattatgg attagaatta attgctacaa agggaaattc agatataaaa
    11281 tttatttgga atgataaaaa caataattct tcaactttta gtaaagaaaa gatagaatcc
    11341 acattaaaaa aagtaaaagg tgtagacata aaaatatctg aagtaaacaa gtcatataag
    11401 aaaaaatatt cacctgcact ctatgattta acagaattac aaagagatgc aaataaaatg
    11461 tttggatttt cagcaaaaga aactttatct ataatgcaaa aactgtatga acatcataaa
    11521 gtacttactt atcctagaac tgattctaga tatttaacat cagatattgt tggaacatta
    11581 aaagatagaa taaaagctgt aaatattagt gattattcaa agacttgtaa taaattatta
    11641 aaaagcaata ttatagctaa taaatcgttt gttgacaatt caaaggtaac agaccatcat
    11701 gcaataatac caacagaaca gaaggtattc atgagtgatt ttagtgacaa agagcgaaaa
    11761 atatataatc ttgtagtaaa aagattttta gcagtactat ctcctccttt tgaatatgag
    11821 cagacaacta taagtgcaac tgtagaagga gaaatattta aggctaaggg aaacaaagta
    11881 ataaatttag gttggaaaga aagttataaa gatattgaag atgaagatga gtatgaaagt
    11941 ataccaaata ttttagaaaa agatgtactt aaggtcaagg gattaaagat aacttcagga
    12001 aaaacaaatc caccaccata cttaaatgag ggaacattat tgactgctat ggaaaagaat
    12061 ggtctaggga cagttgctac aagagcagat ataatagaaa aattattcaa ttcattttta
    12121 atggaaaaga aaaataaaga tatatatata acatcaaaag gaagacaatt attagattta
    12181 gttccagtag acttaaagac accagaactt acagcttcat gggaaaagaa attattggat
    12241 atttcaaagg gaaaacttag taaaaataca ttcataaatg acatgaaaga ttattcaaaa
    12301 gatattgtac tagaagtaaa aaatagtgat aataaattta aacatgataa cttaactaaa
    12361 aatagatgtc cagaatgtgg taaatttatg ttagaggtaa atggtaaaaa aggtaagatg
    12421 ttgatttgtg aagatagaga gtgtaatact agaaaaacta tatcacaagt aaccaattca
    12481 agatgtccta actgccataa aaaattagaa cttcgtggag aaggtgaggg gagaatcttc
    12541 acttgtagtt gcggatacag agaaaagttg tcgtctttca acaagagaaa gcaagaagaa
    12601 aaacagaagg catcaaaaaa agatgttaat caatatttaa aaaatcaaaa taaaaatcaa
    12661 gagacattta ataatccatt tgcagaagca ttagctaagc taaaaaacaa ataattttaa
    12721 agttattatt atacacaatt ataactttaa ctgtatatta gttatatgta ctgatataat
    12781 atagtgtata gtttaggcat gaaagtaggg ctgttaaatg gatttaagtg gcatatttaa
    12841 atactattgt aaagagtgtg aaaatacatg gaataattcg agtgttgaat tatttgagaa
    12901 tatagaaacg tatagtaaag attcacaaaa aaagagggaa aaagaattag ataaattgct
    12961 aaatacaata tcagttcatt tagagaggta tccaagtgat gctgtattga gaaaaatgtg
    13021 ggtaaaaaag ggcgaggttt tcttacaaaa gacattggaa aaagaaaata tttttaagtt
    13081 agaaaaaatg gatgtagagg atagaaaaaa atttttagat ataacaaaac agtttattag
    13141 agatgctaga aaatttgatg atgatttacc tataggtgat attatgcaag ctatgaggaa
    13201 tgtatggatt tcaaatgcat tacaattatt atttggtaaa gaagtatatt attcaaaagc
    13261 taactttgca tatagtatgt tatatccata tactgataat tatttagaca atacaaatat
    13321 agataaaaat gataagattt tatttaataa ctggttagaa aaaaggctcc tgggagaaca
    13381 cattaaatct aaggattatc atgaaagtaa agtatctaaa atgatagatt atattgaaag
    13441 tgtataccct agagaaaagt ttacagaagt ttatgaatcg ttattattaa tatttaaaag
    13501 tcaagtaaat agtttaaaac aacatggtaa ggaaaatcat ttgtgtaaag aagatttatt
    13561 atccatttct attgaaaaag gaggttcatc cgttttagta gatggatatt taataagtgg
    13621 attgatgaca aaggaagaaa tagagttttg tataggatat ggatttttat tacaaatatc
    13681 tgatgattta caagatataa aagaagattt aaaatacaac cataaaacta ttattacaga
    13741 gatgtcaaaa gagggtactt tagataaagt tgtaaataaa ctaataaatt ttactattga
    13801 gttaatagat agttttaaaa ttaataataa aaataaatct gtaataacta tgataaagaa
    13861 tgattgctta atgttaattt tattttctgt agtttataat gctgaatttt tttctgtagg
    13921 atatataaaa gaagtagaga aatttattcc atatacaata gattattcat tagagattga
    13981 agaaaaaata aaagaaaaat ttaaaaatat agatgtttta aataatgaaa atgaatataa
    14041 agaaatgatt gatattattt gtgcagagta gaaaaaaagg gagtgtctta gaatagactt
    14101 tttagtttat gaggcactct ttttgtataa aatcaaatgt attttcatca ttttaataat
    14161 taaaaagagc ttatccctat ttgagaaagc cctttttaat ttaataaaaa tgtcaaggtt
    14221 aaactattta aatgcagtaa taatcccatt atcatgtaag ttttttatga ttgtagctgc
    14281 gatagggaat ccaaataatc cagctattcc aaatagttga gctccaacaa acatacacat
    14341 taatgttatt aaaggatata ggccaatttg gtgtcctact acctttggtt ctaatatttg
    14401 tctaacaacg gttataatta tgtatagtat taaaagtcct attgctaaat taatatttcc
    14461 attaatgagt gagataatca tccaaggtgt caaaatactt cctgtaccca agactggcaa
    14521 aatatcaaca agtgctatga tgacagatat agtaaatgca ttttcaacct ttaggatagt
    14581 aagtccaata agtagttcta tgaatgtcac tgatagtagt attgcatagg cttttagtag
    14641 ttttaaaaga gcattaatac tgctattttt tatatttatt atcataaatt gacttttttc
    14701 tggaaattgt tttaagataa agtttactat tttttgatag tcaaaagtaa agaaaaaaga
    14761 agcaattaaa gtaataataa gttttaacat aaatgcaggt gttttacttg caatactagc
    14821 aatagcattg agtgcatttg ttgaaataga agctactaaa gacatcatag attgacttat
    14881 attatcccaa ccaagtatta atgctaggtt aacattaggt gtactagcat ctatctttga
    14941 aaataaagta tttagcgttg gttgtatact tgatttatat atttcaggaa gtctaaaaaa
    15001 tacatcactt acacttgcaa atatcttcac accaaagcta actaataaaa atatacacaa
    15061 cccataaaaa attaaaagta ttactataga aataagtgta cgatttaaat ttgtattatt
    15121 tgtaataagt cttataatag gtcttaagat ggatgcaatg ataaaactga ttacaaaagg
    15181 cattaataat ggcaataaga attttaatac aatatataca atacttgtta ttaaaactac
    15241 atatgtaaat ttaattataa aattcttttg cttttgaata tccataatat aaaacctcca
    15301 atgtatttga tattattcta aatatggtct tttttacaga aaatatacta ctgtatattg
    15361 attataaact ataaagctta tgtaaagtaa ataaattatg taaaatttag gttaattttg
    15421 tataaagaga tacttttata ttttacaatt aataaccaaa tactaaaaaa tattttaaat
    15481 aaagaactta aaattgtgat aaaattaatt tatagatatt aaaaaaagta taatatatgg
    15541 tttttaagag gtgctaagat gaaaaatttt agagatttag gtgggaacaa aactgaggat
    15601 ggcagaactg taaagaaggg attattttat aggtctgcaa aattatcaaa tctaagtgaa
    15661 aatgatataa agattttaaa agagttaaat attaaatata tatttgatta tagaagtgat
    15721 gaagaagctc gtaaacatcc atcaacaata atatcaaata taaaaaatat aagaatacca
    15781 gcaatgagag agctagaaga atcaggagga agttttggtt ctattgaaga tatgattgat
    15841 ggattgtttg aaaaagatgg tgcatttaat atgttaaata atagttacta taatttgcct
    15901 ataaataatc cgtcatataa aaaattagta gaacttataa gagactattc taatttacca
    15961 atattaaatc attgtacagc tggtaaggat agaactggtg tggggagtgc tataattctt
    16021 atgattttag gggtatcgag agagaatata atgaaagatt atctaaaaag taatgatttt
    16081 gcagataaag agatagaaag atttatagaa tataagccta aatttaagga cattccaaaa
    16141 gaaaatttga aatatatatt tggtgtaaat gaagagtata tgaaaactgc atttagaaga
    16201 attgatgaag aatacattag tgtagaagca tatttatatg gagaatttaa tttaaataaa
    16261 gaagaaataa gaaaattaag aaatcaatat ctagagtaaa aggtgagttt atgagtttaa
    16321 atataacagc aagacagata aatataataa aaatattgtt aaattcaaaa gatacaatta
    16381 gtggtattgc cttaagtcaa gagataggat gttcttcaaa aactatacaa aatgaaataa
    16441 aggatattaa taaacaactt agaaatggta aaattttgtc aataagagga gttggttata
    16501 aactagaagg aagttttgat gaggtaaatc taaatagcaa tctctatgat gatgtagata
    16561 gagtagaata tataatcaga aaaatattaa ccttaagtaa tgaagaaaaa aatactataa
    16621 aacttgaaga tttagccgat tctatgtatg taagtgtttc aacagtaaaa aatgatttaa
    16681 aagaagtaaa aagaatgttg gaaaagtatt caatatcagt taaatctaag cataaacaag
    16741 gtatatgtgt tttagaaagt gaagat
//
LOCUS       DAJMZY010000086        16748 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.086, whole genome shotgun sequence.
ACCESSION   DAJMZY010000086 DAJMZY010000000
VERSION     DAJMZY010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16748)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16748)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16748
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.086"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            578..1228
                     /locus_tag="OE968_002767"
     CDS             578..1228
                     /locus_tag="OE968_002767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic nucleotide-binding domain-containing
                     protein"
                     /protein_id="HCP7220036.1"
                     /translation="MKAEKTSIYPIIKNNLNKISIVEYKKGQRFVASDKDLQEVFFII
                     EGVALVECTTRGGNKFLVDIVPENEFIGKISYIYEHNLKCDIFAKTNIKLFRFEKNVF
                     EEFYLKPDFIALFHRKCTRRIYELYKTRMVRELFSCTEVIAYCISNKQENNVCNIKAI
                     RNFSEIYSISRKSRYHSLLKLTEKEIVKKMGNTYEILNYDELHKLAFEVKEFLEDE"
     gene            complement(1368..2744)
                     /locus_tag="OE968_002768"
     CDS             complement(1368..2744)
                     /locus_tag="OE968_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HCP7220037.1"
                     /translation="MQELFSLKDENKRFYKILLSLCIPIIIQNLISTSVNVIDTIMIS
                     SLGETSVASVGVANQFFFLFNMSLSGITGGAGVFISQFYGKKDVSNIRKVTGLTCVLA
                     IVLSFVFVIPALLTPKPIIHIFSYDSEVVKLCIDYFSIAVFSYPLIAVSTVFSTGSRG
                     VRNPKLGMICSAFALVTNVILNYGFIFGNFGLPALGVKGAALATVIARICELILMITY
                     VYLYKKDYILKFGLKNLKAIDKIFIKSFSSKSFPIFVNDSVWAIGTVLYSVAYARAGT
                     SAIAASQIATSTGNFFIMTAVCIASGASIMLGNELGADHIKRAIEYAKKFSILVFSAG
                     LILGIILILNIPLLLKMFSVSDSLASDITKIFFIMGILMALKSFNTLVIIGILRSGGD
                     TKYALFLELGCMWLASIPLTFIAAFKGAPIFVLVLLTYSEEVVKFIFGVPRALSKKWA
                     INIVKEID"
     gene            complement(2760..4673)
                     /locus_tag="OE968_002769"
     CDS             complement(2760..4673)
                     /locus_tag="OE968_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HCP7220038.1"
                     /translation="MIVLSCNNLNKSFGIDSILENISFTVNEGDKIGIIGVNGTGKTT
                     LFKIISGIYGYDSGDIYTSKDCEIGYLEQNTNFYSDNTILEEVLEVFKNLIEMESYLR
                     ELEVKISEESTKTNSPIIEKIMDEYSHKLELFSDLNGYGYKSEAKGVLKGLGFSDNDM
                     DKPISILSGGEKTRVLLGKLLLKKPTLLLLDEPTNHLDSEAIEWLEVFLKQYKGTVML
                     ISHDRYFLDQSVNRIFEVHNKKLKVYNGNYSKFVELSKIEKELELKKFEDQQKEIKKQ
                     EESIERLKAYGREKHLKRARSKEKALDKVDVLDKPEAYRKKARIQFTPSVQSGNDVLQ
                     IRDVSMGYGERILFKDLDLDIYRGEKVALIGANGVGKSTLFKIITNELQPLSGNIKFG
                     TNVHVSYFHQEQKTLNLDNTIIDEIWENNTHLTQTTLRNMLGAFLFVDEEVFKKISTL
                     SGGERARVAILKLILSNANLLLLDEPTNHLDIDSKEVLEEALTNYDGTIFTISHDRYF
                     LNTVVDKILVLDENGITEYLGNYDYYIDKKRQIQEMSIIEEKEEKTRTQIKDEKRKER
                     EQREIEKKNRIKRQNIEKEIEKLEIEIEKLDILLCQEEVYSNPDKAKEVSQEKINLEN
                     NLASLYDEWEEFM"
     gene            4809..5441
                     /locus_tag="OE968_002770"
     CDS             4809..5441
                     /locus_tag="OE968_002770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HCP7220039.1"
                     /translation="MLGNKNISMAVIRRLPKYHRYLGDLLDRDIQRISSKELSDIIGF
                     TASQIRQDLNNFGGFGQQGYGYNVEALHTEIGKILGLDRPYNAVLVGAGNLGQAIANY
                     AGFRKAGFEIKALFDANPRMIGLKIREFEVLDSDTLEDFIKNNNIDIAVLCIPKNGAQ
                     EVINRVVKAGIKGVWNFAPLDLEVPKGVIVENVNLTESLFTLSYLMKEGK"
     gene            5580..6119
                     /locus_tag="OE968_002771"
     CDS             5580..6119
                     /locus_tag="OE968_002771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraR/DksA C4-type zinc finger protein"
                     /protein_id="HCP7220040.1"
                     /translation="MVFVEELWKKAIEFHGHECPGLAIGFKAALAAKKYLGCKQSGDE
                     EIVCISENDACGIDGIQVVLSCTMGKGNLLLRMTGKSVYHFFNRENGKSIRIYVKSKP
                     FEMDREGYKRYLLESDFEEIFEITDTKLRLPEKARIFKSLKCEVCGEFASEQYIRIEE
                     GKKVCLDCFDKYERFYEEY"
     gene            complement(6295..6465)
                     /locus_tag="OE968_002772"
     CDS             complement(6295..6465)
                     /locus_tag="OE968_002772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004619190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HCP7220041.1"
                     /translation="MAYKITDACISCGACEAECPVSCISAGDDAYVIDAGSCIDCGSC
                     AGACPVDAPQPE"
     gene            6750..7817
                     /locus_tag="OE968_002773"
     CDS             6750..7817
                     /locus_tag="OE968_002773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HCP7220042.1"
                     /translation="MKNKLVYICIMSLLLFVVGCSNNPNKESTIKKDSKNNQSQVKEE
                     KREPVKKDITISFAGDVTMGNYKGSSYYGSFDHEFKRQGEDYNYFLKNVKPVFEKDDL
                     TVVNLEGPLTTASNAKEKKFAFKGKPGYVNILKSGSVEAVSIANNHSEDYFEEGMKDT
                     QFILDENKINYFGLGKDAVVDVKGIKVGLLGYNGLSTEYNEKNLKQMEDDIKSLKKKS
                     DVVVVYFHWGIELDYYPDKKQKDFAHYAIDKGADLVMGSHPHVIQGIEKYKNKYIAYS
                     LGNFCFGGNKNPSDTDSYIYQQTFTFSDNKLTSIKEPNIIPTSITSSNSRNNYQPKIL
                     DGSEKDRVLNKLEKISKDLNK"
     gene            7987..9888
                     /gene="cooS"
                     /locus_tag="OE968_002774"
     CDS             7987..9888
                     /gene="cooS"
                     /locus_tag="OE968_002774"
                     /EC_number="1.2.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic carbon-monoxide dehydrogenase
                     catalytic subunit"
                     /protein_id="HCP7220043.1"
                     /translation="MACNTCKMCESADKKLESFVASKDVETAFHRTEDQKVKCGFGLQ
                     GVCCRLCSNGPCRVTPKSPRGICGADADTIVARNFLRAVASGAACYLHVVENTAKNLK
                     NVGITKGVVKGEKTLNQLAEMFGIESDEKYDKCIKVADKVINDLYKSRDDKMELVEKI
                     AYAPRVKKWKELGIMPGGAKSEVFDAIVKSSTNLNSDPVDMLVNCLNLGISTGLYGLT
                     LTNLLNDVMLGEPVIRMAPVGFNVIDPDYINIMITGHQHSTFANFQDRLKDEDVIKLA
                     QSVGAKGFKLVGCTCVGQDLQLRGEHYQEVFAGHAGNNFTSEAVLSTGAIDIVLSEFN
                     CTIPGLEPIADKYKVKMVCLDDVAKKANAECIGLDRSKLDELSNTLIEKALESYKERR
                     GSIEIDIPKDHGFEQSLTGVSEKNLKAFLGDSWKPLINLIAEGKIKGVAAVVGCSNMT
                     AGGHDVNTVELTKELIKKDIIVLSAGCSTGGLENVGLMSPGAEELAGENLKEVCKTLG
                     IPPVLNFGPCLAIGRLEIVATELAAELGIDLPQLPLVLSAPQWLEEQALADGAFGLAL
                     GLPLHLALPPFITGGKLVTEVLTEKLKDLTGGHVIVNPDPKSSANQLEEIIIDRRKNL
                     GLKDVECNA"
     gene            9881..10354
                     /locus_tag="OE968_002775"
     CDS             9881..10354
                     /locus_tag="OE968_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HCP7220044.1"
                     /translation="MHRIFINKDLCTGCKSCVLACMLKHNKDYDMYTLDLENIDNDSR
                     GHIELDSRHNNPVPILCRHCDEPECVLACMSGAMHKDSESGIVSYDEEKCGSCYMCVM
                     SCPYGLLKPDDRSKQNILKCDLCKDEEYPRCVANCPSGAIELQKEENDELCSVRG"
     gene            10329..11555
                     /locus_tag="OE968_002776"
     CDS             10329..11555
                     /locus_tag="OE968_002776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HCP7220045.1"
                     /translation="MNYVVLGASAAGINAVKTLRELDKDSNIVVISKDENVYSRCMLH
                     HVISEHRTLKQINFVDEDFMEQNNVKWIAGKTVKGIDINKKVVQTEDITVNYDKLLIA
                     TGASSAIPPIKNLRDGNFVYSVRNIDDIYKIKEKAQNSKNVVIIGAGLVGIDALVGLF
                     KYEQLNISVAFMEKYILDRQLDEYTASVYENKFKEKGVKFYPSASIQEIVLDNSKNVT
                     GVAFSNGEVLDADMVIVATGVKPNADFLDGTGIEYDRGIIIDDMCQTTQKDIYAAGDV
                     VGKNAIWPLAVKQGIVAAYNMVGKDKKIEDEFAFKNSMNFMDIPTISIGMNTPVDDSY
                     KVLTRHGINDYKKFVFKDNVIYGAVIQGDISYVGVLTYLIKNKVEIYDLENRIFDICY
                     ADFFNIKENGEFCYSV"
     gene            complement(11694..12881)
                     /locus_tag="OE968_002777"
     CDS             complement(11694..12881)
                     /locus_tag="OE968_002777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HCP7220046.1"
                     /translation="MNITKNFLKDYLEKFGETPFLVRLKDEEEFLIGEGSPQFKVIVN
                     NDISKSELLKSTSLALGEAYINRDIEVEGDLFLTLNLLLKQIDKFNIDNSAVKHLLHS
                     SNSMRHQKKEIHAHYDIGNDFYSLWLDKTLSYSCAYFRNDNDTLYDAQVNKVHHILTK
                     LNLEEGMSLLDIGCGWGFLLIEAAKKYKIHGVGITLSEEQFKEFNARIKEENLQDYLE
                     VRLMDYRELKKSDLMFDRVVSVGMLEHVGRENYELFIKNVNAVLKDGGLFLLHYISGL
                     QESYGDPWIKKYIFPGGVIPSLREMIHICSDYKYHTIDVESLRLHYVKTLLYWQKNFS
                     ENLPKIKEMFDDKFIRMWDLYLCSCAAAFNTGIIDIHQILFTKGIKNDLPLTREYMYN
                     CSK"
     gene            13154..13978
                     /locus_tag="OE968_002778"
     CDS             13154..13978
                     /locus_tag="OE968_002778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HCP7220047.1"
                     /translation="MEVYALVGSSGTGKSFKALEFAYENDIEYIIDDGILIYKNKVLA
                     GISAKQANTTIEAVKRAIFYNLEHRQEVREAIKKENIRKILIIGTSKKMVNQIVERLS
                     IGRVCKFINIQDISTKYEIEIAKQARKEGNHVIPVPAVEIKSMASGLSINSLKRLFRK
                     GNNRNMVVLEKTIIRPTFSYIGKFYISADVIKQIIEYEVYNFGSIDRINKINIENCNN
                     FMNIFVSININDLETIKKIEDIQQTIKKSIEKMTLVNVQKIDINIHKIKKINFLQC"
     gene            14107..15372
                     /gene="gluD"
                     /locus_tag="OE968_002779"
     CDS             14107..15372
                     /gene="gluD"
                     /locus_tag="OE968_002779"
                     /EC_number="1.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-specific glutamate dehydrogenase"
                     /protein_id="HCP7220048.1"
                     /translation="MSGKDVNVFEMAQSQVKNACDKLGMEPAVYELLKEPMRVIEVSI
                     PVKMDDGSIKTFKGFRSQHNDAVGPTKGGIRFHQNVSRDEVKALSIWMTFKCSVTGIP
                     YGGGKGGIIVDPSTLSQGELERLSRGYIDGIYKLIGEKVDVPAPDVNTNGQIMSWMVD
                     EYNKLTGQSSIGVITGKPVEFGGSLGRTAATGFGVAVTAREAAAKLGIDMKKAKIAVQ
                     GIGNVGSYTVLNCEKLGGTVVAMAEWCKSEGSYAIYNENGLDGQAMLDYMKEHGNLLN
                     FPGAKRISLEEFWASDVDIVIPAALENSITKEVAESIKAKLVCEAANGPTTPEADEVF
                     AERGIVLTPDILTNAGGVTVSYFEWVQNLYGYYWSEEEVEQKEEIAMVKAFESIWKIK
                     EEYNVTMREAAYMHSIKKVAEAMKLRGWY"
     gene            15585..16175
                     /locus_tag="OE968_002780"
     CDS             15585..16175
                     /locus_tag="OE968_002780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M56"
                     /protein_id="HCP7220049.1"
                     /translation="MHFKSKDLNLKYLVLFLKIVYWFNPFICIMEKYMDLDCELYCDE
                     RVLKNCTVQQKQEYALTIVNSMKRSTNFSNKFVAGLNKQSDIRKRVINMFSEKHKNGI
                     LRALIISLFSSITFFKFDSTSIIEENDFLERSRYTFEGRQEDMFVTIDFIYADVPIKL
                     RKEHEENCRVNGIVPKDSDSIEIIPRFYKDCMDLKK"
     gene            16505..>16748
                     /locus_tag="OE968_002781"
     CDS             16505..>16748
                     /locus_tag="OE968_002781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M56"
                     /protein_id="HCP7220050.1"
                     /translation="MSNFILNGIFRTVIVSSLSILLILIFKKNVFKRFSKKFNYYIWM
                     IVVIKLFLPFTYYTFTINILRSKKHININNINLEGFN"
BASE COUNT         6423 a         1994 c         2697 g         5634 t
ORIGIN      
        1 tatctattaa tatttataga atctccaaaa actaatttca aattattttc taaaaagtct
       61 attaaatctt ttctactatc atttaccaga gctactgatt ttttcattta tttctcctta
      121 tataataaat agtttccaac aaaatagttg tataaagcaa tctaattttg ataatttaaa
      181 tttatcaaat aaaaaagaaa gtgtctataa tgactttcta aaagttgcat taagacactt
      241 tctttcttat agttaaaaat cttgtcacca aatcccccta attgttgctt aaaacttaaa
      301 ctgtatgtat atttttcatt tctattcgat taaattataa tatacaccca aaaaaattta
      361 ttttaataaa ttctattgat aatataattt tataaatata gaattatatt aaaataaatt
      421 atatatgaaa atatatatgt ataagtttat tctgcgtgag tagaatggat ttgtcaagtt
      481 taatttagtt gtaattctat cttttattaa aaataacata aattaaaaca tataaataaa
      541 atattttata caatatattg taaaggaggt aactttgatg aaagcagaaa aaacaagtat
      601 atatccaatt attaaaaata atttaaacaa aatatcaatt gttgaatata aaaagggtca
      661 aagatttgta gcatcagata aagacttaca agaagtgttc tttataatag agggagttgc
      721 attagtggag tgtactacta gaggaggaaa taaatttctt gttgacattg tacctgaaaa
      781 tgaatttata ggcaaaatta gttacatata tgaacataat ttgaaatgtg atatatttgc
      841 aaagactaat ataaaattat ttcgatttga aaaaaatgta tttgaagagt tttatctcaa
      901 accagatttt attgcactat ttcacagaaa atgtacaaga agaatatatg aattatataa
      961 aaccagaatg gtaagagaac tattttcttg cacagaagtt attgcctatt gtatatcaaa
     1021 taaacaagaa aataatgtct gcaatataaa agctattcgt aatttcagtg aaatctattc
     1081 aattagtaga aaaagtagat accattctct gctaaagtta actgaaaagg agatagtaaa
     1141 aaaaatgggt aatacatatg aaattttaaa ctatgatgaa ttacataaat tggcatttga
     1201 agtaaaagaa tttttggaag atgagtaaaa attgttactt aatcaaaata aagtataata
     1261 atttctgtaa aaaatagaaa tagtctcact gaaaatcaaa aatactttag ttattttcaa
     1321 tgagactgtt tagaaatatt gtatacttat aatgtatagt ataattatta atcaatttcc
     1381 tttactatat taatagccca ttttttagat aatgctctag gaacaccaaa tataaactta
     1441 accacttctt cactataagt gagcaaaacg agtacaaata taggtgcacc tttaaatgca
     1501 gctataaaag ttagaggaat agaagctaac cacatacatc ctaattctaa aaatagagca
     1561 tatttagtat ctcctccact tcttaaaata ccaattataa ccaatgtatt aaaagattta
     1621 agagccatta gtattcccat tataaagaat atcttagtta tatcagaagc taagctatca
     1681 gaaacactaa acatttttaa taataatggt atatttaaaa ttaaaataat tccaagtatt
     1741 aaaccagctg aaaatacaag tatagaaaac tttttagcat attcaatggc tcttttaata
     1801 tggtcagctc caagttcatt tccaagcata atagatgcac cagatgcaat acatacagct
     1861 gtcattatga agaaattacc tgtactggtt gctatctggc tagctgctat agcagaagta
     1921 ccagctcttg catatgcaac agaatacagg acagttccaa ttgcccatac agagtcattt
     1981 acaaatatag gaaagctttt tgatgaaaaa gattttataa aaattttatc aatagctttt
     2041 agatttttta gaccaaactt taatatatag tcttttttat aaaggtaaac ataagtaatc
     2101 attaaaatta attcacatat tctagcaata acagtagcta gagcagcacc ttttacaccc
     2161 aatgcaggaa gaccgaagtt accaaatata aatccataat ttaaaataac atttgttaca
     2221 agtgcaaatg cactacaaat catacctaac ttaggatttc taacacctct tgaaccagta
     2281 ctaaatacag tacttacagc aattaatgga taactaaata ctgcaatact aaagtaatct
     2341 atacaaagtt ttaccacctc agaatcatac gaaaatatgt gtataattgg ctttggtgtt
     2401 agtaaagcag gaataacaaa tacaaaactt aaaacaattg ccaatacaca agtaagacct
     2461 gtgacttttc ttatattact cacatccttc tttccataaa actgtgaaat aaaaactcca
     2521 gcacctcctg tgataccaga taaggacata ttaaaaagaa agaaaaattg gtttgcaact
     2581 ccaactgaag ctacagatgt ttcccccaaa ctacttatca taattgtatc tattacattt
     2641 acagaagtag aaattaagtt ctgtatgata ataggtatac ataaagatag aagtatttta
     2701 taaaatcttt tattttcgtc ttttaaagaa aatagttctt gcaaataatc ctctcctttt
     2761 tacataaatt cttcccactc atcatataga gaggcaaggt tattttctaa attaattttt
     2821 tcttggctaa cttctttagc tttatctgga ttagagtata cttcttcttg acataaaagt
     2881 atatctaatt tttcaatttc aatctctaac ttttcaattt ctttttctat attttgtctt
     2941 tttattctat ttttcttttc tatttctctt tgttctctct cttttctttt ttcatctttt
     3001 atttgagttc tagttttttc ttctttttct tctataatac tcatctcttg gatttgcctt
     3061 tttttatcta tataataatc ataatttccc agatattcag taattccatt ttcatctaaa
     3121 actaaaattt tatcaacaac agtatttaga aagtatctat catgtgatat tgtaaatata
     3181 gtcccatcat aattagttaa ggcctcttca aggacttcct tagaatcaat atctaggtga
     3241 ttagtaggct catctaataa caataagttt gcatttgata gtataagttt aagtatggca
     3301 actctagctc tttctccacc actcaatgta gaaatcttct taaaaacttc ttcatctaca
     3361 aataaaaatg cccctaacat atttctcaaa gtagtttgag taagatgagt attattttcc
     3421 caaatctcat caattattgt gttatctaaa ttaagagttt tttgttcctg atggaagtag
     3481 gaaacatgta cattagttcc aaatttaata ttgccactaa gaggttgtag ttcattagtt
     3541 attattttaa ataatgtaga tttgccaaca ccatttgcac ctataagtgc aactttttcc
     3601 cctctatata tatctaaatc caagtcttta aaaagtattc tttctccata acccatagat
     3661 acatctctaa tttgaagaac atcattacca ctctggacag aaggcgtaaa ttgtatacga
     3721 gcttttttcc tataagcttc tggtttatct aaaacatcta ctttgtctaa tgctttttct
     3781 ttacttcttg cacgctttag gtgtttttct ctaccataag cttttagtct ttcaattgat
     3841 tcttcttgct tttttatttc tttttgttgg tcttcaaatt tcttaagctc tagttctttt
     3901 tctattttag ataactcaac aaatttagag tagttaccat tatatacttt aagcttttta
     3961 ttgtgaactt caaaaattct atttacggat tggtctaaga aatatctatc atgagatatt
     4021 aacatgacag tccctttata ttgttttaaa aatacttcta accattctat tgcttcagag
     4081 tctaagtggt tagtaggttc atcaagtaac aatagagttg gtttcttaag aagtaatttt
     4141 cctaaaagaa ctctagtttt ttcaccacca gaaagtatgc ttattggctt atccatatca
     4201 ttgtcactaa atcctaatcc ctttagaact cctttggctt cagatttata tccatatcca
     4261 tttaaatctg aaaataattc tagtttatgt gaatattcat ccatgatttt ttctataatt
     4321 ggagagtttg tttttgtact ttcttcagat attttaacct ccaattctct taaataggat
     4381 tccatttcta tcaaattttt aaaaacttct agtacttctt ccaaaatagt attatccgaa
     4441 taaaaattgg tattttgttc taaatatccg atttcacaat ctttagaagt gtaaatatct
     4501 ccactatcat atccataaat tcctgaaatt attttaaata aagtagtttt tccagtacca
     4561 ttaacaccga ttataccaat tttatcgcct tcatttactg taaaactaat attttctaat
     4621 atagaatcta taccaaaact tttatttaag ttattacatg acaaaacaat cataaatttc
     4681 tacctccttg aactatctaa aattataatg ttttgatata atataatcaa ggttatatgt
     4741 attagttttg aaaaagaaat attttattgt gaatcaaaca aaaaagagga cacttttagg
     4801 aggtgaagat gttgggaaat aaaaatatat caatggcagt tataagaagg ctcccaaaat
     4861 atcatagata tcttggagac ttattagata gggatataca aagaatatct tctaaagaat
     4921 tgagtgatat aatagggttt accgcttctc aaataagaca agatttaaac aactttggtg
     4981 gatttggaca acaaggatat ggttataatg tagaagctct tcatactgag ataggtaaaa
     5041 ttcttgggtt ggatcgacca tacaacgcag ttcttgtagg agcaggtaac ttaggacaag
     5101 ctatagccaa ttatgcagga tttagaaaag ctggattcga gataaaagct ttatttgatg
     5161 caaatcctag aatgataggt ttaaagataa gagagtttga agtattagat tcagatactt
     5221 tagaagactt tataaaaaac aataatatag atattgctgt attatgtata cctaaaaatg
     5281 gagcacaaga agttattaat agagttgtaa aagctggaat caaaggtgta tggaattttg
     5341 cacctttaga tttagaagtt ccgaaaggtg ttatagttga aaatgtaaac ttaacagaaa
     5401 gtttatttac cttatcgtat ttaatgaaag aaggaaagta gacaacttaa acatattaat
     5461 aatgagcagt tgtaaagagt attgagaaag tcagaagatt taatattaaa tcctctggct
     5521 ttttgaaata ttaggataaa aatttaaata atgtatggaa ataaacaata ttaaggagag
     5581 tggtttttgt ggaggaatta tggaaaaagg caattgaatt tcatggtcat gaatgtccag
     5641 ggttagctat aggatttaaa gcagcacttg cagcaaaaaa atatttagga tgtaaacagt
     5701 caggagatga ggaaattgta tgtatttctg aaaatgatgc ttgtggaata gatggtatac
     5761 aagtagtgct aagttgcaca atgggtaagg gaaatttact acttaggatg actggaaaat
     5821 cagtatatca tttctttaat agagaaaatg gaaaatctat aaggatatat gtaaagtcaa
     5881 aaccatttga gatggataga gaaggataca aaagatattt attagaaagt gattttgaag
     5941 aaatatttga gattacagat actaagttaa gacttcctga aaaagcaaga atatttaaat
     6001 cccttaaatg tgaagtgtgt ggtgaatttg catctgagca atatataagg attgaagaag
     6061 gaaagaaagt atgtcttgat tgttttgata aatatgaaag attttatgaa gagtattaaa
     6121 attataaatt agattaaagt taaaagtatt agatatgtgc taacagtatt ttaagatgaa
     6181 ttaggtagca acataataaa gtatataaat aatattaatt gaatcataca taattaaaaa
     6241 gaggctgatt agtatttata aaataaaatc agtctcttta tgaataacga attattattc
     6301 tggttgaggt gcatctacag gacaagctcc tgcacaagaa ccacagtcta tacaagaacc
     6361 agcatctata acatatgcgt cgtctccagc tgatatacag ctaacagggc attcagcctc
     6421 acaagcacca cagcttatac aagcgtcagt aattttatat gccattttga aatcctccct
     6481 tttatatgta ttgtaattca ataacattat aacaaatatt attgaatata acaattaaat
     6541 taattctaca acaaaaactt tattatgata ttcttgtttt aaagttttac aataaagttt
     6601 aatctgctta tatttttatt tattttaaag aagtttattt taaaaataaa attaaattta
     6661 aaaagttatg tattgattat atttaaaaat gttatactct aaaaaagtat attttattta
     6721 aaaatttatt aatacaaagg agatttacta tgaaaaataa attagtttac atatgtatta
     6781 tgagtctatt gctatttgta gtaggatgtt ctaataatcc aaataaggaa agtaccatta
     6841 aaaaagactc taagaataac caaagccaag ttaaagaaga aaaaagagaa cctgtgaaaa
     6901 aagatataac tataagtttc gctggtgatg taactatggg gaactataaa ggttcatcat
     6961 attatggcag ttttgaccat gaatttaaaa gacaaggaga agattacaat tattttctta
     7021 aaaatgtaaa acctgtattt gaaaaagatg acttaacagt ggttaattta gaaggtccac
     7081 ttactacagc gtcaaatgca aaagaaaaaa aatttgcatt taaaggaaag cctggatatg
     7141 taaatatttt aaaatctgga agtgtagagg cagtaagtat tgcaaataat cattcagaag
     7201 attattttga agaaggaatg aaagatacac agtttatatt ggacgagaat aaaataaatt
     7261 attttggatt agggaaagat gctgttgtag atgtcaaagg aattaaagtg ggtctattag
     7321 ggtataatgg attatcaact gaatataatg aaaaaaattt aaaacaaatg gaagatgata
     7381 ttaagtcctt aaaaaagaaa tcggatgttg ttgtagtgta ctttcattgg gggatagaat
     7441 tagattatta tccagataaa aaacaaaaag attttgctca ttatgctata gacaagggag
     7501 cagatttagt tatggggtct cacccacatg tgattcaagg aatagaaaag tataaaaata
     7561 agtatatagc ttatagtcta gggaattttt gctttggagg aaataagaat ccttctgata
     7621 cagatagtta tatatatcaa caaaccttta ctttttcaga taataaatta acttcaatta
     7681 aagagccaaa tataatacca acttcaataa catctagtaa ctccagaaat aattatcaac
     7741 caaaaatatt ggatggaagt gagaaggata gagttttaaa taaacttgaa aaaataagca
     7801 aagatttaaa taaataaaat gtaaaaaaaa ataaatatat atatttattt taataattta
     7861 tattttgttt agggtatggt aaatcgtggt attaaataag tagattttaa tagttaaatt
     7921 atagtcaatt ataataaagc tatttaatct acttttttaa tataaaaata taagggggaa
     7981 tttgtaatgg cttgtaacac ttgtaaaatg tgcgaaagtg cagacaagaa attagaaagt
     8041 tttgtagctt caaaggatgt tgaaacagca tttcatagaa cagaagatca gaaagttaag
     8101 tgtggttttg gacttcaggg ggtttgttgt agactctgtt caaatggacc atgtagagta
     8161 actcctaaat caccaagagg tatatgtgga gcagatgcag acactatagt agcaagaaac
     8221 tttttaagag cagtagcatc aggagcagct tgttatttac atgtggtaga aaatacagct
     8281 aagaatttaa aaaatgttgg aataactaaa ggtgttgtta aaggagaaaa aacattaaat
     8341 caattagcag agatgtttgg aatagaaagt gatgaaaagt atgataaatg tataaaggtt
     8401 gcagacaaag ttatcaacga tttgtataaa tcaagagatg ataaaatgga attagtagaa
     8461 aaaatagctt atgcacctag agtgaaaaag tggaaagagt taggtataat gcctggtggt
     8521 gcaaagtcag aagtttttga tgcaatagta aaatcatcaa caaatttaaa cagtgaccca
     8581 gtagacatgc tagttaattg tttgaactta ggtatatcaa caggattata tggtcttaca
     8641 ctaactaatc ttttaaatga tgttatgttg ggagaaccag ttataagaat ggctcctgta
     8701 ggatttaatg taatagaccc agactacata aatataatga taacaggtca tcaacattca
     8761 acatttgcaa atttccaaga tagattaaaa gatgaagatg ttataaaatt agctcaatct
     8821 gttggcgcaa aaggatttaa gttagtagga tgtacatgtg ttggtcaaga tttacaatta
     8881 agaggagaac attatcaaga agtatttgct ggacatgcag gtaacaattt tacaagtgag
     8941 gctgttttat caactggagc aatagatata gttctttcag aatttaactg tactatacca
     9001 gggcttgaac caatagcaga taaatataaa gtaaaaatgg tttgtttaga tgatgttgct
     9061 aaaaaagcga atgcagaatg cataggttta gacagaagta aattagatga acttagtaac
     9121 actttaatag aaaaagcatt ggagtcttat aaggagagaa gaggaagtat tgaaatagat
     9181 ataccaaaag accatggatt tgaacaatct ttgactggtg taagtgaaaa gaacttgaaa
     9241 gcgtttttag gagattcatg gaaacctctt attaatttaa ttgcagaagg aaaaattaaa
     9301 ggtgttgcag ctgttgtagg atgttcaaat atgacagcag gaggacatga tgtaaatact
     9361 gttgaactta ctaaagaatt gattaaaaaa gatataatag tactatctgc aggatgttct
     9421 actggaggat tagaaaatgt tggtcttatg tcacctggag cagaagaatt ggcaggagaa
     9481 aacttaaaag aagtatgtaa gactttagga ataccaccag tattaaactt tggaccatgt
     9541 ctagctatag gaagactaga aatagtagca acagaattag cagctgaact tggaattgac
     9601 ctaccacaat taccattagt gctttcagct ccacaatggt tggaagaaca agcattagct
     9661 gatggagctt ttggtcttgc ccttggctta cctcttcatt tagctttacc tccatttata
     9721 acaggaggaa aattggtaac agaagtatta acagaaaaat taaaagactt aacaggagga
     9781 catgttatag tgaatccaga ccctaaatct tcagctaatc aattagaaga aataataata
     9841 gatagaagaa aaaatttagg gttaaaggat gtggaatgca atgcatagaa tttttataaa
     9901 taaagattta tgtacaggat gtaagagctg tgtactagca tgtatgctaa aacacaataa
     9961 agattatgac atgtacactc ttgatttaga aaatatagat aatgatagta gagggcatat
    10021 agaattagat agtagacata ataatccagt tccaattctt tgtagacact gtgatgaacc
    10081 tgaatgtgta ttagcatgta tgagtggtgc aatgcataaa gatagtgaaa gtggaatcgt
    10141 ttcatatgat gaagagaaat gtggttcatg ttatatgtgt gtaatgtctt gtccatatgg
    10201 attattaaag ccagatgata gaagcaagca gaacatactt aaatgtgatt tatgtaaaga
    10261 tgaggagtat cctagatgtg tagctaattg cccaagtgga gcaattgaat tacagaagga
    10321 ggaaaatgat gaattatgta gtgttagggg ctagtgcagc tggtataaat gcagtaaaaa
    10381 cattaagaga attagataaa gattcaaata tagtagtaat ttctaaagat gaaaacgtat
    10441 attcaagatg tatgttgcat cacgttatat ctgaacacag aactttaaaa caaataaatt
    10501 ttgttgatga agattttatg gagcaaaata atgtaaaatg gattgcaggt aagactgtta
    10561 aaggtataga cataaataaa aaggtagttc agacagaaga cattactgta aattatgata
    10621 aacttttaat agctacaggt gcatcttctg ctattcctcc tataaaaaat ttaagagatg
    10681 gaaattttgt atattctgtg agaaacatag atgatattta taaaataaaa gaaaaagcac
    10741 aaaattctaa aaatgtagtt ataataggtg ctggtttagt tggtatagat gcattagtgg
    10801 gattatttaa atatgagcag ttaaatattt ctgtagcttt tatggaaaag tacattttag
    10861 atagacaatt ggatgaatat acagcatcag tgtatgaaaa taagttcaaa gaaaaaggtg
    10921 taaaatttta cccaagtgca tcaatacaag aaattgtatt ggataacagt aaaaatgtta
    10981 caggtgttgc attttcaaat ggtgaagttt tagatgcaga catggtaatt gtagctacag
    11041 gggttaaacc aaatgctgac tttttagatg gaacaggaat agaatatgat agaggtataa
    11101 taatagatga tatgtgccaa acaacacaaa aagacatata tgcagcagga gatgttgtag
    11161 gtaaaaatgc tatttggcct ctggcagtaa agcaaggaat tgtagctgcc tataatatgg
    11221 ttggaaaaga taagaagata gaagatgaat ttgcttttaa aaatagtatg aatttcatgg
    11281 atataccaac tatttctata ggaatgaata cacctgtaga tgatagctat aaagtattaa
    11341 ccagacatgg aattaatgat tataaaaagt ttgtttttaa agataatgta atctatggag
    11401 cagttataca aggagatatt tcatatgtag gtgtattaac ttatttaata aaaaataaag
    11461 ttgaaatata tgatttagaa aataggatat ttgatatatg ttatgcagac ttttttaata
    11521 taaaagaaaa tggagaattt tgttatagtg tatagtatat acgtggagta aggtttataa
    11581 atacagtaaa tcaataaata gagttattct aaaataagaa aaatgacaaa tcttatttag
    11641 aaatagctct attttttgta attaaattta aattatattc aatttgtaaa atattatttt
    11701 gaacaattat acatatactc tctagttaga ggtaaatcat tttttatacc tttagtgaaa
    11761 agtatttgat gtatatctat aataccagtg ttgaaagcag cagcacaaga acaaaggtat
    11821 aaatcccaca ttcttataaa cttatcatca aacatttctt taatctttgg aagattctca
    11881 gagaaatttt tttgccagta tagtaaggtt tttacataat gtaatcttaa actttctacg
    11941 tctatagtat gatatttgta atcactacaa atatgtatca tttctcttag gctaggaata
    12001 actcctcctg ggaaaatata tttttttatc caagggtctc cataagattc ctgcaatcca
    12061 cttatatagt gaagtaaaaa caatccacca tcttttaaaa cagcatttac gtttttaatg
    12121 aaaagttcat agttttctct accaacatgt tcaagcatcc caacgcttac aactctatca
    12181 aacataaggt ctgatttttt taattctcta tagtccataa gtcttacctc aagatagtct
    12241 tgaaggttct cttctttaat tcttgcgtta aattccttaa attgctcttc gctaagtgta
    12301 attccaacgc cgtgaatttt atattttttt gcagcttcta ttagtaaaaa tccccaacca
    12361 caaccaatat cgagaaggct cataccttcc tctaaattta gtttagttaa tatgtggtga
    12421 actttattga cttgagcatc ataaagagta tcattatcat ttctaaagta tgcacaagaa
    12481 taactaagtg tcttatctaa ccataagcta taaaaatcgt tgccaatgtc atagtgggca
    12541 tgtatttctt tcttttgatg tctcattgaa tttgatgagt gcaatagatg ttttacagct
    12601 gaattatcaa tattgaattt gtctatttgt tttaaaagta gatttaaagt taagaataaa
    12661 tctccctcaa cttcaatgtc tctatttatg taggcttctc caagtgctaa agatgtactt
    12721 tttaatagtt cagacttgct aatatcatta tttactataa ctttgaactg aggggagccc
    12781 tctccaatta gaaattcttc ctcatcttta agcctaacta gaaatggtgt ttcaccaaat
    12841 ttctctaaat agtcttttaa aaaatttttt gtaatattca tattaccagc tccttctaat
    12901 gtaaatccag taagtttccc tgcttaaaat atattatagt ccttttttta aaaaagtaaa
    12961 attttttcaa taaatttttt atttaaagga aatttatttt ttgtaaagaa atttcatgtt
    13021 gtagtatatt ttttgcttat aaattttggt actggatata atattaaact gttaatgata
    13081 taataaattt aatctataaa gtaaataaaa ttttgtaata aatagttaaa gctattttat
    13141 aaggagatat atgatggaag tatatgcttt ggttgggtca agtggcacag ggaagagctt
    13201 taaggcttta gagttcgcat atgaaaatga tatagaatat ataattgatg atgggatttt
    13261 aatatacaaa aacaaggttt tagctgggat atcggcaaaa caagcaaata ctactataga
    13321 agcagttaaa agggctattt tttataatct ggagcataga caagaagtta gagaagcaat
    13381 taaaaaagaa aatataagaa aaattcttat tattgggaca tcaaaaaaaa tggttaatca
    13441 aattgtagag agattgtcaa ttggaagggt ttgcaagttt ataaatatac aagatataag
    13501 tactaaatat gaaatagaaa tagcaaaaca agctagaaaa gaaggaaatc atgtaattcc
    13561 tgttccagca gttgagataa aaagtatggc aagtggtctt agtataaatt ctttgaagag
    13621 actttttaga aaaggaaata ataggaatat ggtagtttta gaaaaaacaa ttataagacc
    13681 aacttttagt tatataggaa agttttatat tagtgctgat gtaattaaac agattattga
    13741 atatgaagta tacaactttg gaagcattga tagaataaat aaaatcaata tagagaattg
    13801 caataatttt atgaatattt ttgtaagtat aaatatcaat gatttagaaa ctataaaaaa
    13861 aattgaagac atacaacaga caataaaaaa gtctattgag aaaatgactt tagttaatgt
    13921 acaaaaaata gatattaaca ttcataaaat taaaaaaata aacttcctcc aatgttaaaa
    13981 aataaactga gaaaatgata tactaatttg caataaagtg tgctataatt aaactgtaaa
    14041 tttaggaaat ggttttttct aaatggagta tacataatta taacgtattt ataagggggc
    14101 tttcaaatgt caggaaaaga tgtaaatgtc ttcgagatgg cgcaatctca agtaaaaaat
    14161 gcatgtgata aattaggtat ggaaccagca gtttatgaat tattaaaaga acctatgaga
    14221 gttatagagg tttcaattcc agtaaaaatg gatgatggtt ctataaaaac ttttaaagga
    14281 tttagatcac aacataatga tgcagtaggg ccaacaaaag gtggaataag attccatcaa
    14341 aatgtttcaa gagacgaagt aaaagcttta tctatatgga tgactttcaa gtgttctgta
    14401 acaggtatac catatggtgg aggtaaaggt ggaataatag tagatccatc aactttatct
    14461 caaggtgaat tagaaagatt aagtagagga tacatagatg gaatatataa attaataggt
    14521 gagaaagttg acgttcctgc accagacgta aatactaatg gtcaaataat gtcttggatg
    14581 gttgatgagt acaataaatt aactggacaa agttctatag gtgttataac tggtaagcca
    14641 gttgaatttg gtggttcttt aggaagaaca gctgctactg gatttggtgt tgctgttact
    14701 gcaagagaag ctgctgctaa attaggaata gatatgaaaa aagctaaaat agctgttcaa
    14761 ggtataggaa acgttggttc ttatacagtt cttaactgtg aaaaacttgg tggtactgtt
    14821 gtagctatgg ctgaatggtg taaatcagaa ggttcttatg ctatatacaa tgaaaatggt
    14881 ttagatggtc aagctatgtt agattatatg aaagaacatg gtaacttatt aaacttccca
    14941 ggagctaaga gaatatcttt agaagagttc tgggcttcag atgttgatat agtaatacca
    15001 gctgcattag aaaactctat aactaaagaa gttgctgaat ctataaaagc taaattagtt
    15061 tgtgaggctg ctaatggacc aactactcca gaggctgatg aagtatttgc tgaaagagga
    15121 atagttctta ctccagatat attaactaat gctggtggag ttacagtttc ttacttcgag
    15181 tgggtacaaa acttatatgg atactactgg tcagaagaag aagtagagca aaaagaagaa
    15241 atagctatgg ttaaagcatt tgaatctatt tggaaaatca aagaagagta caatgttaca
    15301 atgagagaag ctgcttacat gcattcaatt aagaaagttg ctgaagctat gaaattaaga
    15361 ggatggtact aagatttact cttaataaat aataggatat aattatttaa gatataaagg
    15421 ggctgtacat agtacagccc ttaaattatg tggcttacaa tgaagtaagc tatttttgtt
    15481 ttaacttata aataacttga taaattatgt aatttagaat gtatttttta ccaccacatg
    15541 attacaaatt agaggagtta gattgaattt ttagacatga acttatgcat tttaaaagca
    15601 aagaccttaa tttaaagtat ctagtattat ttttaaaaat agtatattgg tttaatccat
    15661 ttatatgtat aatggaaaaa tatatggatt tggattgtga actttattgt gatgagagag
    15721 ttttaaaaaa ttgtactgta caacaaaagc aagaatatgc tctaactatt gtaaattcaa
    15781 tgaaaagaag tacaaatttt tcaaataaat ttgtagctgg attaaataaa caatctgata
    15841 ttagaaaaag agtaataaac atgttcagtg aaaaacataa aaatggtatc ttaagggctt
    15901 tgattataag cttgttttct tctattacat tttttaaatt cgattcaact agtattattg
    15961 aagagaatga tttcttagag aggtcaagat atacgtttga aggaaggcaa gaagacatgt
    16021 ttgtaacaat agattttata tatgcagatg tacctataaa acttagaaaa gagcatgaag
    16081 aaaactgtag agtcaatgga atagtaccaa aagattcaga ttcaatagaa attattccta
    16141 gattttataa agattgtatg gatttaaaaa aataagttag acttaatatt gatgttgata
    16201 ttatgaattt tttatattta agcaattgaa aattttatta tagattcaat tttatatgtg
    16261 tttaagtatg aaatttatag atagttgaaa taattaaata tgattgatgc ataggaatca
    16321 ttactaagct ataattaatt ataggggagt ttaaataaat tatgagttac acaatcataa
    16381 aatgataaaa atagttatct gttacaaaaa atgtatcttt ttaattaata aagataatat
    16441 gaaaacttaa aaggcaaata aacttaaata taaaatactc ttaaataaga taggagaaaa
    16501 atgtatgtct aactttattc taaatgggat ttttagaaca gttatagtaa gtagtctaag
    16561 cattcttctg atattgattt tcaagaaaaa tgtatttaaa agatttagca aaaaatttaa
    16621 ttattatata tggatgatag ttgttattaa attattttta ccatttacat attatacttt
    16681 tacaataaat atcttgagaa gtaaaaaaca cattaatatt aataacataa atttagaggg
    16741 atttaata
//
LOCUS       DAJMZY010000087        16714 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.087, whole genome shotgun sequence.
ACCESSION   DAJMZY010000087 DAJMZY010000000
VERSION     DAJMZY010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16714)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16714)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16714
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.087"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            complement(<1..199)
                     /locus_tag="OE968_002782"
     CDS             complement(<1..199)
                     /locus_tag="OE968_002782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HCP7220051.1"
                     /translation="MALILPKGLPVINKLLDEGIDVIYKEDFKKELKYEENIDTKIAI
                     LNLMPIKIDTELDLLRRIDKTG"
     gene            complement(229..1494)
                     /locus_tag="OE968_002783"
     CDS             complement(229..1494)
                     /locus_tag="OE968_002783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase"
                     /protein_id="HCP7220052.1"
                     /translation="MYNKETICVQGNYKPGNGEPRVLPLYQSTTFKYSSIDQLAELFD
                     LKVDGHIYSRISNPTIQAFEEKISLLEGGVSSVAVSSGQSANMLAVLNICKSGDSILC
                     SSKVYGGTFNLLGPSLKKFGIDLISFDLDSSEDEIVELAKENTKVVFAETLANPTLEV
                     IDFEKIANVAKRINVPFIVDNSLASPVLCNPLKYGANIVTHSTTKYLDGHASSVGGII
                     VDGGNFNWDNGKFPELVEPDPTYHGISYTQKFGNAAYATKARVQLLRDYGNCLSPFNA
                     YLTNLNVETLHLRMERHSENALKIARFLEKHENVDWINYPGLEDNKYYENAKKYLSRG
                     CSGVLSFGVRGGLENAKKFVEKLQIASLVTHVSDVRTCVIHPASTTHRQLTEEQLIAS
                     GVLPSLIRLSVGIENVEDLIADLNQALNF"
     regulatory      complement(1604..1706)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            complement(1760..4417)
                     /locus_tag="OE968_002784"
     CDS             complement(1760..4417)
                     /locus_tag="OE968_002784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HCP7220053.1"
                     /translation="MENHKQMPWHSRATHEILESLDSSEEGLTDTEAEKRLKENGLNE
                     LRKKPPRTTLQMLWSQITDAMVMILIGAAILSLIFGEFTEAFVILIIVTVNAVIGIVQ
                     EKKAESSLEALKNMNSPTARVMRDGEENVIPASNLVVGDIVFLEDGAMVPADLRLIET
                     SSLKIQEASLTGESVPSEKDADTILPKECVLGDRSNMAYTSSIVTYGRGVGVVVATGM
                     DTEVGNIAHLLDSQDDFDTPIKRKLNTVGKTLSVIGIIVCVVIFAIGAFYQRPLLPMF
                     MIAISLAISIIPEGLPATATIVMALGVQRMAKRNALIRKLPAVETLGGATVICCDKTG
                     TLTLNKMTVTHIAVNGDFESGKVTSIDTASEKHPLVYKEIVYAGALCNDACINPDKTD
                     EILGDPTEGALIFMAKKFGIDQEALEEEYPRVFEQPFDSDRKCMTTVHNIDEKIIAYT
                     KGAVDEILDLCTKILTSKGERNITEVDKKNIHELCLNMSKDALRVLGFAKREISSIPK
                     EDSENIEYDLTFIGMVGMIDPPRTEVIDAVSTCKEAGIRTIMITGDHKVTATTIAHEL
                     GIWSEENTVISGDELDNLSDDELDEAVKNTTVFARVSPFDKLRIIQSLKRIGEVPAMT
                     GDGVNDSPALKSADIGIAMGISGTDVAKDSSDMILMDDSFTTIAYAIKEGRRVYRNIQ
                     KVIQFLLVGNIAEILTLFVAILLNWDTPLLAVHILWVNLATATLPALALGVDPPSRNI
                     MKHQPVKSTTLFEKNLIQRVVTQGIFVAIMTILAYKIGLNIENHSVGQTMAFCVLAFS
                     QMLRAFSQRSNTDSMFNRNNGKNPFLLISFLTSAFLIAVILFAPVFRNAFNLTVLNNL
                     EWLITIVLAIMSVIQVEVGKIIKRKKLKK"
     gene            complement(4545..5288)
                     /gene="yaaA"
                     /locus_tag="OE968_002785"
     CDS             complement(4545..5288)
                     /gene="yaaA"
                     /locus_tag="OE968_002785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HCP7220054.1"
                     /translation="MIIMLSPAKNMKNIEVFDRDLSLPCFIDNTKEIVENIKTFGIED
                     FKNKMKINEKLAVLNKNRFESIKFDRLGNPAILTYDGIQYKNIEAENFTRKDEEFANS
                     CIRIISGLYGVVKPYDSIYEYRLEMQTKLRVGEFKNLYEYWGNRIYKELIKEKTAIVN
                     LSSNEYSKSIEKFIKDSDTYITCTFKVNKNGILKVESTQAKKARGMMTKYIVKNRIRD
                     IEELKKFNLEGYKYKENLSNNSEYIFVKE"
     gene            complement(5298..5762)
                     /gene="bcp"
                     /locus_tag="OE968_002786"
     CDS             complement(5298..5762)
                     /gene="bcp"
                     /locus_tag="OE968_002786"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002586316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-dependent thiol peroxidase"
                     /protein_id="HCP7220055.1"
                     /translation="MLSIGTKAPEFTLEDKDGNKVSMSDFKGKKVVVYFYPKDNTPGC
                     TRQACAFRNAYDGFKKEDIQVIGISKDSIKSHQKFAEKHELPFILLSDPDLVAIKAFD
                     VWKEKKMYGKTALGVVRATYIIDENGIIEKVFEKAKPDTNAQEILEYLEKQE"
     gene            complement(6114..7619)
                     /gene="ade"
                     /locus_tag="OE968_002787"
     CDS             complement(6114..7619)
                     /gene="ade"
                     /locus_tag="OE968_002787"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HCP7220056.1"
                     /translation="MSPGFIDAHMHIESTMVMPIELSKKLLKSGTTTIIADPHELVNV
                     KGVSAIDFLLESTKDIPLNVYIMVPSSVPATSFETNGVGKFSAKDMESYVNNPRILGL
                     GEVMCFNDVINSENEILDKLELFKNKVVDGHAPNINGKSLQTYVCAGIENDHECITFD
                     EVYEKLRAGLKILIREGSAAKNLKSIVSGMLKHNLPIEEFMFCTDDKHLDDIEKQGHI
                     RWNIKCAIDLGMEPVRAIKVATYNSAKAYGLRKIGAIGAGYKADIVVLNDLDKMEVDS
                     VYKDGNLVNEEMFSNYNYEIKDKELLNTVKFKYINKEKIQLKVSEKNYVMEIVPYQIL
                     TNKVYESLPCADGYFVPNKEYSKLCVVERHRMTGNVAVAPLKGFGIKNGAIATTVAHD
                     SHNIIVAGDNDDDILVAINYLKEIQGGYVIVSNGKVLAHLSLQVAGLISTFTAEEVQE
                     ITDNMLEIARKMGVPEYVDPFITLSFMALPVVPQIRLTDLGLFDVEEFKFI"
     gene            complement(7752..8870)
                     /locus_tag="OE968_002788"
     CDS             complement(7752..8870)
                     /locus_tag="OE968_002788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCP7220057.1"
                     /translation="MIVVEKAYKFRMYPNKKQQELINKTFGCCRFVYNKYLAKRIDVY
                     KKHKETFTYKQCSSDLTNLKKELKWLKEPDKFSLQNALRDLDNAYKKFFKEKAGFPKF
                     KSKKINRFSYKTNFTNGNIMYCGQHIKLPKLGMVKVRDKQVPQGRILNATISKEPSGR
                     YYVSLCCTDVDIGAFENTNNHIGLDLGIKEFCISSCGDFIENPKYLKKSLNKLAKLQR
                     ELSRKTIGSLNRNKARLKVARFQEHIANQRKDFLQKLSTKLIKENDIICIEDLQVKNM
                     IRNRKLSRLISDVSWSEFIRQLEYKANWHGRQIVKVGKFFASSQICNKCGYKNEEVKD
                     LNIREWICPSCNETHDRDINASINILKEGLRLITIQNK"
     gene            complement(9519..9695)
                     /locus_tag="OE968_002789"
                     /pseudo
     CDS             complement(9519..9695)
                     /locus_tag="OE968_002789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728625.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
     gene            complement(10001..11155)
                     /locus_tag="OE968_002790"
     CDS             complement(10001..11155)
                     /locus_tag="OE968_002790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenic efflux protein"
                     /protein_id="HCP7220058.1"
                     /translation="MEMLISASEEAFLHVGSMIGFFILLFGYINYKTSGNFTNIISKN
                     RKFQPLIGALIGAIPGCGGSLAIMPLYINGKLSFGAIIASLIASMGDAAFVLISSNIK
                     MYFFVTIVSTITGIITGQLVDYFKLEEKLGLKNRRKSDKYDISKNNPKENKEQHNHDE
                     IILDTLAKSHGNTNRLAFIITHGKGYKIYIGIIVIGFIFMSLAHSGLNLPIIEKLHSL
                     EEVIAVIGILFSIIYMWCFKKVFKNSNQKEEENKKISLREMLIHSVGEISFVITWIFI
                     AYLIYDLIILILGGDEYLVKLVLSTGVISVFIGAGLGLIPGCGIQIVLMSFYLKGTIP
                     LGAVIANSISQDGDALFPLLAMDKKSSLWAMIITTIPAILVGMIVYAFLG"
     gene            complement(11400..12239)
                     /locus_tag="OE968_002791"
     CDS             complement(11400..12239)
                     /locus_tag="OE968_002791"
                     /EC_number="1.17.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-3-methylbut-2-enyl diphosphate
                     reductase"
                     /protein_id="HCP7220059.1"
                     /translation="MNIKIAKNAGFCFGVKRAMKMAWDEVEKNDSGIYALGPLIHNKQ
                     AVAKYEEKGLKTVNEIDTIPNHENMIIRSHGVPENIYKEAKDKKLKIVDTTCPFVKKI
                     HTVVSEYHNKGYEIIVIGDMKHPEVIGINGWCENSAIIIKTLEQMENMEFDNSKRYCL
                     VAQTTINPELYISIVNKLSDKLEEIVFNDTICSATKTRQESAKELAKKVDCMIVIGGK
                     HSSNTQKLVKVCEDLVPTFAIETKDELDVNTLKKYKNLGITAGASTPNWIIEEVVTFL
                     ENL"
     gene            complement(12252..12848)
                     /locus_tag="OE968_002792"
     CDS             complement(12252..12848)
                     /locus_tag="OE968_002792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HCP7220060.1"
                     /translation="MNFYRFVINIFKGFSKIFFKYEVIGAENIPDRGNIVIASNHKSN
                     LDPIFLAAAIENREIAAIAKKELFKVKPLGFILKKLHVMPINREKPDVSTIKTILRSV
                     RDGYVLGIFPEGTRIKGDSFGKAKAGLSVFTIKSKSKVVPVSIISKYKLFSKVIVYIG
                     EPISFEEHFKEKLSNDDHERISQEILEVIKQNYFKYSK"
     gene            complement(12899..13549)
                     /locus_tag="OE968_002793"
     CDS             complement(12899..13549)
                     /locus_tag="OE968_002793"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HCP7220061.1"
                     /translation="MGNLVIAVDGPAGAGKSTIAKIVAKKLNINYIDTGAMYRAVTYK
                     CLKSGIDVNNEKEVIQIAENSDIDFKDNNIYLDKEVINEEIRTIEVSNNVSNVAKIKE
                     VRQLMVEVQRKIGMKNSVILDGRDIGSYVFPDADYKFFLVATPEERGNRRYKELCNKG
                     YNTTLEEVIEDIIRRDEIDSNREFAPLVKANDALEIDTTGKTIEEVVEEVVSKINL"
     gene            complement(13595..14848)
                     /locus_tag="OE968_002794"
     CDS             complement(13595..14848)
                     /locus_tag="OE968_002794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HCP7220062.1"
                     /translation="MSKVIVVGGGASGMMAALSASKNNNEVILVERNGELGRKLRATG
                     GGRCNFTNNREIEDFFDKVVSNKKFLYSSFYTFTNKDLISYFESRNLEYKIEEENDHK
                     VYTKNDKSIEVIEVLNKDLLNHNVKIMYNKKVIDIITEEIALKDDSNKDKSKYLIKGI
                     ILDNGDKILGDKVIISTGGVSYSKTGSDGSMYKILKKHGHTLNKLYPALVPLTIEEKW
                     IKDLQGISMKNVEISCKIKKRKISKSGDMLFAHFGITGPCVLIMSSYINKIIEKEKVE
                     LNIDFLPNLSTDEISSIIRAFPNKNVLNNLKQILPQNFLKEIFSLLSLVDKKASDLSK
                     ADEIRIIEYIKNMKLTCNGTTGINTGMVTSGGISVKEINSSTMESKLVKNLFFTGEVI
                     DIDAETGGYNLQIAFSTGYLAGISV"
     gene            complement(14872..15513)
                     /locus_tag="OE968_002795"
     CDS             complement(14872..15513)
                     /locus_tag="OE968_002795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HCP7220063.1"
                     /translation="MGNTFYIVRHGQTDWNILGKTQGHGNSDLTPQGIEQAKELSEDI
                     GKYSIDYIFSSDLGRAMQTAQILGDKLNIEVQKTEALREMGFGVWEGLLIKEIQKDYS
                     DIYATWRNEPHLVNIPEGETLKIIKERVDAFIKELNEKYDNKNIILVTHSITLRVMLL
                     SFLESGMENIYRIKQDNTALNIVEFKDYGPVIVKMNDTSHIKNHVKINNSALE"
     gene            complement(15715..16128)
                     /locus_tag="OE968_002796"
     CDS             complement(15715..16128)
                     /locus_tag="OE968_002796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1653 domain-containing protein"
                     /protein_id="HCP7220064.1"
                     /translation="MLELKNNLGISERKLKYPCIYKHFKGKYYATMGLSKAIDHIENI
                     CEIYGKENLIQNRNKYKLVIRHTEREEDIYVYRDLDGNFYHKKEEDTNDLVLYKTLYD
                     DTGIFARPLDMFLEKVDTDKYVNSIQEYRFEEVYK"
     gene            complement(16279..16620)
                     /locus_tag="OE968_002797"
     CDS             complement(16279..16620)
                     /locus_tag="OE968_002797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family transcriptional regulator"
                     /protein_id="HCP7220065.1"
                     /translation="MKEENFINVEYEDKRFSINSKEVLYIEKQEYEVKIYTESGNYEV
                     GENAPCIRKLLKEENFFKCSNSYIVNLDKCEFYLSNNCIFVNNNFIRILGSERKKKLK
                     KKLEKLYDYED"
BASE COUNT         5195 a         2996 c         1796 g         6727 t
ORIGIN      
        1 atcctgtttt atctatcctt cttagtaaat ctaattctgt atctatcttt ataggcatta
       61 gatttagtat agctatctta gtgtctatgt tttcttcata ctttaattcc tttttaaaat
      121 cttctttata aattacatct attccttcat ctaataattt attaataaca ggtaatccct
      181 ttggtagtat taaagccata tcttttcact tctctttctc ttagaatatt agaaatttaa
      241 agcttgattt aaatcagcta ttaaatcctc tacattttct attccaacag ataatcttat
      301 tagtgaaggc aatactccag atgcaattaa ttgttcctct gttaattgtc tatgagtagt
      361 tgaagctgga tgtataacac aagttcttac atctgaaaca tgtgtaacca aagatgctat
      421 ctgtaatttt tccacaaatt ttttggcatt ttctaaccca cctcttactc caaatgataa
      481 aacaccacta catcctcttg ataaatactt tttggcattc tcataatact tgttatcttc
      541 aagtcctggg taattaatcc aatctacatt ttcatgtttt tctaaaaatc tagctatttt
      601 aagtgcattt tcactatgtc tctccattct aagatgtagt gtttcaacat ttaaattagt
      661 aagatacgca ttgaatgggc ttaaacaatt tccatagtct ctaagcaact gaactcttgc
      721 tttagttgca tatgcggcat ttccaaattt ttgagtatag cttataccat gatatgttgg
      781 gtctggctca actaattctg gaaattttcc attatcccag ttaaagtttc caccatccac
      841 tataattcct ccaacacttg aagcatgccc atctaaatat tttgtggtag aatgagtaac
      901 tatatttgct ccatacttta aagggttaca aagcactgga gatgctaatg aattatcaac
      961 aataaatgga acattaattc tcttagctac atttgctatt ttttcaaaat ctatgacttc
     1021 aagagttgga tttgcaagtg tttctgcaaa cacaacctta gtattttcct ttgcaagttc
     1081 tactatctca tcttcacttg aatctaagtc aaacgatatt aaatctatac caaatttttt
     1141 aagactaggt cctagtaaat tgaatgttcc tccatatact tttgaagaac aaagtatact
     1201 atctcctgat ttacatatat ttaaaactgc caacatattt gcagattgcc ctgatgatac
     1261 agctacagaa gatactccac cctctagtaa acttattttt tcttcaaaag cttgaatagt
     1321 aggattgctt attcttgaat atatatgtcc atcaactttt aaatcaaata attcagcaag
     1381 ttggtctata ctgctatatt taaaagttgt actttgatat aaaggtagta ctcttggttc
     1441 tccattacct ggtttataat ttccttgcac acatattgtt tctttattat acattcttgt
     1501 atccccctta gattttagta aaaaaaatta aactatttac cagatgagag ttaaaataaa
     1561 taaagcctga gtatataact caggctctgt ataagcttaa ttatactcat ctctcagctt
     1621 tcgccgcagg atttagcacc actgtatata aatatactgg ttgccgggtt tcatagggcc
     1681 agtccctcca cctctctgga taagatttat ttaatttttc tatgttttat atcttatata
     1741 tttttcctaa ttttgtcaac tattttttta atttttttct tttaataatt ttcccaacct
     1801 ctacttgaat tacagacatt atggctaaaa caatcgttat aagccactct aagttattta
     1861 aaactgttaa gttaaaagca tttctaaaaa caggtgcaaa tagtattact gctattaaaa
     1921 atgcagaagt taaaaatgag attaaaagaa atggattttt accattattt ctattaaaca
     1981 ttgaatctgt atttgaacgc tgactaaatg ctcgtaacat ctgtgaaaat gctaatacac
     2041 aaaatgccat tgtttgacct acagaatgat tttctatatt aagaccaatt ttatatgcta
     2101 aaatagtcat tattgccaca aatatacctt gggtaacaac tctttgtata agattttttt
     2161 caaacaaagt ggttgatttc actggctggt gcttcattat atttctgctt ggtgggtcaa
     2221 ctccaagagc aagggctgga agcgtagcag ttgcaaggtt tacccataga atatgaacag
     2281 caagaagcgg agtatcccaa tttaataata ttgctacaaa caacgtaagt atctctgcta
     2341 tattaccaac aagcaaaaat tgtataactt tttgtatgtt tctatataca cgtctacctt
     2401 cttttattgc ataagcaatt gttgtaaaac tatcgtccat taaaatcatg tcagaagaat
     2461 cttttgcaac atctgtacca cttataccca tggctatacc aatatcagca gactttaagg
     2521 caggagagtc atttacacca tccccagtca ttgctggtac ttctccaatt ctttttagag
     2581 attgtataat tctaagttta tcaaatgggg atacacgagc aaatactgta gtatttttaa
     2641 cagcttcatc tagttcatca tcactcaaat tatcaagttc atcaccagat atcacagtat
     2701 tttcttcact ccatattcct aactcatgag cgattgttgt ggcagtaact ttatggtcac
     2761 ctgttatcat tatggttctt atacctgctt ctttacaagt acttactgca tcaattacct
     2821 cagttcttgg tgggtcaatc ataccaacca tacctataaa tgttaaatca tattctatat
     2881 tttcactatc ttcttttggt atagatgaaa tctcacgctt agcaaaacca agtacacgca
     2941 atgcatcttt agacatgtta agacataatt cgtgtatatt ctttttatcc acttcggtaa
     3001 tgtttctttc accttttgaa gttaatattt tagtacatag gtcaagaatt tcgtctactg
     3061 ctcctttagt ataagcaata atcttttcat ctatattatg aacagttgtc atacattttc
     3121 tatctgaatc aaaaggctgt tcaaatacac gtggatattc ttcttcaaga gcttcttgat
     3181 ctattccaaa ttttttggcc ataaaaatta atgcgccctc tgttgggtca cctaatattt
     3241 catctgtttt atctggatta atacatgcat cattacaaag tgcaccagca taaacaatct
     3301 ctttatacac taatggatgt ttttcagatg cagtatctat tgatgtcact tttccagatt
     3361 caaaatctcc attgacagca atatgtgtaa cagtcatttt atttaaggtt aacgtaccag
     3421 ttttatcaca acatattact gtagctcctc ctaatgtttc aacagcaggt aattttctaa
     3481 ttaaagcatt tcttttagcc atacgctgta cgcctaaagc cattacaata gtagctgttg
     3541 caggtaatcc ctctggaata attgatatgg caagggaaat tgcaatcata aacattggca
     3601 agagaggtct ctgataaaat gcacctattg caaatataac aacgcataca ataataccta
     3661 tgacacttaa tgtctttcca acagtattaa gtttacgttt tataggagta tcaaaatcat
     3721 cttgtgaatc taaaagatgt gctatgttac ccacttctgt atccatacca gttgctacta
     3781 caacacctac acctctacca tatgtgacta ttgaagatgt atacgccata ttgctacggt
     3841 ctcctaatac acattcttta ggtaagattg tatctgcatc tttttctgat ggaacagatt
     3901 ctcctgttaa agaagcctct tgaattttta aacttgatgt ttctattaaa cgaaggtctg
     3961 ctggaaccat agctccatct tctaaaaaaa caatatctcc tactacaaga ttacttgctg
     4021 gaataacatt ttcttcacca tcacgcataa cacgagctgt aggtgagttc atatttttta
     4081 atgcttctaa tgatgattct gcttttttct cttgaacaat tccaataact gcatttactg
     4141 ttacaattat tagtattaca aaagcttctg taaattcgcc aaatatcaaa gataatattg
     4201 ctgctcctat tagtatcata accatagcat ctgtaatttg actccaaagc atttgtaaag
     4261 ttgttctagg tggttttttt ctaagttcat ttaagccatt ctctttaagc cgtttttccg
     4321 cctcggtatc ggtgagcccc tcctctgatg aatctagact ttctaaaatt tcatgcgttg
     4381 ctcttgaatg ccaaggcatc tgtttgtgat tttccatttt ggaagaccac tcctttcttt
     4441 ttttaattta agaataatta tattttaaaa tcaagttcaa ttcaatacac actaagtata
     4501 ttttacctaa atttaacaat gccatttaat atttaacaaa acttctactc ttttacaaat
     4561 atgtattcac tattgttaga taagttttct ttatacttat aaccttctaa attaaacttt
     4621 ttcagttctt caatatctct tatcctattt tttacaatgt attttgtcat catacctcta
     4681 gctttctttg cttgtgtaga ttccactttt aatatgccat ttttatttac tttaaaagta
     4741 catgtaatat atgtatcact atctttaata aatttttcta tggatttgct gtattcattt
     4801 gatgaaagat taacgatagc tgttttttct ttgattagtt ctttatatat acgatttccc
     4861 caatattcgt ataaattctt aaactcacct actcgtaatt ttgtctgcat ttctaatcta
     4921 tattcatata tactatcata tggttttaca acaccataca atccacttat gattcgaata
     4981 cagctatttg caaactcttc atctttcctt gtaaaatttt ctgcttctat atttttatat
     5041 tgtattccat cataagttaa gattgcaggg tttcctaatc tatcaaattt aatgctttca
     5101 aatctatttt tatttaatac agctaatttt tcattaattt tcattttatt tttaaaatct
     5161 tctataccaa atgtctttat attttccact atttcttttg tgttatctat aaagcaaggc
     5221 aaactcaaat ctctatcaaa tacttctata ttcttcatat ttttagctgg tgataacatt
     5281 ataatcataa attcttatta ctcctgtttt tccaaatatt caagaatctc ttgtgcattt
     5341 gtgtctggtt ttgctttttc aaagactttt tcaataattc cattttcatc tataatatat
     5401 gtcgcacgta caactcccaa tgcagttttt ccatacattt ttttctcttt ccatacatca
     5461 aaagctttta tagcaactaa gtcagggtca gaaagtaaaa taaaaggaag ttcatgcttt
     5521 tctgcaaatt tttgatgtga ttttatacta tctttactta tcccaataac ttgtatatct
     5581 tcctttttaa atccatcata tgcatttcta aaagcacaag cttgacgtgt acatcctggt
     5641 gtattatctt taggataaaa atatactact acttttttgc ctttaaaatc tgacatactt
     5701 accttatttc catctttatc ttctagtgta aattctggtg cttttgttcc tatactcaac
     5761 ataaatatct ctccttttgt ttttattaat aattttatac tatgcttata ttattaccct
     5821 ataaatctat atataaataa aatattttat tttttatgta taaagtttca taaatatata
     5881 attttcatgt atttatatgt taaaatagac tgaaaatagt tttattaaga tatctatgct
     5941 taaaacaagg ttaaatgata gattaattaa aataaggata tctaaaaata aaatttttag
     6001 ttcatgagat gctctttttt gtatgaaatc aaatatattt ttatcatttc aacaataaaa
     6061 agagacttat ccctattttg agaaagcctc atttattatt acttttatat tatctatata
     6121 aatttaaatt cctcaacatc aaatagacct aaatctgtaa gtcttatttg tggaacaact
     6181 ggaagtgcca taaaagaaag tgtaataaaa gggtctacat actctggaac tcccattttt
     6241 cttgctatct ccaacatatt atcagtaatt tcttgtactt cttcagctgt aaaagtacta
     6301 attaatccag ctacttgaag acttaggtgt gcaagaactt ttccatttga tacaattaca
     6361 taaccacctt gtatttcctt taagtaattt atagctacta gaatatcatc atcattatcc
     6421 cctgcaacta taatattatg agaatcatgg gccacagtag tagcaattgc tccatttttt
     6481 atgccaaatc cttttagtgg agcaactgct acatttccag tcattctatg tctctcaaca
     6541 acacaaagtt ttgaatactc tttatttgga acaaaatatc catctgcaca tggtaaagat
     6601 tcatatacct tatttgtcaa aatttgataa ggtacaatct ccattacata atttttttca
     6661 cttactttta actgtatttt ttctttatta atatatttaa acttgactgt attaagcaat
     6721 tctttatctt taatctcata attgtaatta gaaaacatct cttcgtttac caaattacca
     6781 tctttatata cactatccac ttccattttg tctaaatcat tcaatacaac aatatctgcc
     6841 ttataacccg cacctattgc tccaattttc cttaacccat atgcttttgc agaattataa
     6901 gttgcaactt ttatagccct aacaggttcc atacctaaat caatcgcaca ttttatattc
     6961 catcttatgt gaccttgttt ttctatatca tctaagtgct tatcatctgt gcaaaacata
     7021 aattcttcaa ttggcaagtt atgctttagc ataccactta ctatagactt taaatttttt
     7081 gctgcgcttc cttctcttat taaaattttt aatcctgctc tcaatttttc atatacttca
     7141 tcaaaagtta tacattcatg gtcattttct attcctgcac atacatatgt ctgaagtgat
     7201 ttaccattta tattaggtgc atgtccatct acaactttat ttttaaaaag ctctagttta
     7261 tccaagattt cattttcaga atttataaca tcattaaaac acattacctc tcctaaacct
     7321 aaaattctag gattatttac ataactctcc atgtcttttg cactaaattt accaactcca
     7381 ttagtttcaa aacttgttgc aggtacggat gaaggcacca taatatatac attaagtggt
     7441 atatcttttg tcgattctaa taaaaaatct attgcactaa ctccttttac attgaccaac
     7501 tcatgtgggt cggctatgat agttgtcgta cctgatttta ataatttttt cgataattca
     7561 attggcatta ccattgtaga ttcaatatgc atatgtgcat caataaagcc aggtgatata
     7621 tatttattgc tacactgaac ctcccatgac taaagtcaca gggttcctgc ttcacagaat
     7681 tttgcatact aaaatatgtc ttactaattc tccacaggct atccccgtag ttcctacggt
     7741 tcttacatac gttatttatt ttgaattgtt attagtctta atccttcttt taatatattt
     7801 atacttgcat ttatatctct atcgtgagtt tcattacaac taggacaaat ccattctctt
     7861 atatttaagt ccttcacttc ctcgttttta tacccacatt tattgcatat ttgtgaactt
     7921 gcaaagaatt tacctacctt tacaatttgt ctaccatgcc aattagcctt gtattctaat
     7981 tgacgaataa actctgacca tgacacatca gaaattaagc gagatagttt acgatttcta
     8041 atcatattct ttacttgtaa atcttctatg caaataatat cattctcttt tattaattta
     8101 gtagataatt tttgtagaaa atcctttctt tgattagcta tatgttcttg aaatcttgca
     8161 acttttaatc ttgctttatt tctatttaaa ctaccgattg tttttctcga taattctctt
     8221 tgtaatttag caagtttgtt taatgacttc ttaagatact taggattttc tataaagtct
     8281 ccacaacttg agatacaaaa ttctttaatt cctaaatcta aacctatatg attattagta
     8341 ttttcaaatg ctccaatatc tacatcagta cagcataatg atacataata tctaccactt
     8401 ggttctttag atatagtagc attaagtatt ctaccttgag gtacttgttt atcccttacc
     8461 ttaaccatac caagtttagg tagttttata tgttgaccac aatacataat gtttccattt
     8521 gtaaagttag ttttatatga aaatctatta attttctttg atttaaattt aggaaatcct
     8581 gctttttctt taaagaattt tttatatgca ttatctaaat ctcttaaggc gttttgtagt
     8641 gaaaatttgt caggttcttt aagccacttt aattcttttt ttaaattggt caaatcagaa
     8701 ctacactgtt tataagtaaa agtttcttta tgttttttat aaacatctat tcttttagca
     8761 agatacttat tatacacaaa tctacaacat ccaaaagttt tgttaattaa ctcttgctgt
     8821 tttttatttg gatacattct aaacttataa gctttttcca ctactatcac ctcactttaa
     8881 ttgttttttg atacactttt taatgatttt atcatattta atatattata taatgctgtg
     8941 gtgaacaatt tattaatcac ctataataat gttaacaaat gtaattattt aaaacaatta
     9001 tttagaaggt tttatattta attttaaata acatatttaa gaaccgtaag tcttaacttt
     9061 tatcattttt gaggttgtcg ttcacataag ttcgctacta cctatgcagt tctcttatga
     9121 acttcttaca ctttcatgca agcacagact atatcttatc cttcagcatt atccgttaag
     9181 gtctacccac ttccactacc aatagcttgt agtgtacttc cctcaagagg aatagtcgtt
     9241 gaagtttctc ctattcggag tttacctgct gattgcccat tttaaagtac ttagggttta
     9301 accttatacc atctaaccaa ttttttctac tttcgtaact ttcacactta ggtttatttc
     9361 atccttatgt tttagtttga ttagctttag gggtttccag caattcaagt agtattggat
     9421 aggttctatc ctatctctac atataggttt ccctatatgc tgactatttt agctactaac
     9481 tcatgactaa agtcacgagt gtgcgtagct attttttaat caatttctac attgcccttg
     9541 taatcgccaa ttccaacgat agtgtctcct actattgcta catctcctgt tattaactct
     9601 tctgtaaata catttatgat tgtcccattt tttagtacaa tgtcagcttt ttctcttcca
     9661 cttgaaacat cacactgtct ttttaaatta cccattttta caactcctcc taagtttttt
     9721 atatcaatat actgactgta ttacgtatta tagtttaatt tattaatata tattatatat
     9781 gagttttgat agaaagtatc acttgaaatt tgttccataa ttcctttaat taaatagaga
     9841 gaacatgagg aataatatta tctcccatgt tctcattaat atttaagcaa taatttaatt
     9901 catattgaat tttttatttt tatatttaat cttcactatt cttataaata aatttatgtg
     9961 ctttattatt tttttaatac ttctttattc ataattatat ttaacctaaa aatgcataaa
    10021 ctatcatacc tacaagtatt gctggtatag tagtaataat catagcccat aaagaagatt
    10081 ttttatccat tgctaaaagt gggaaaagtg catctccatc ttgagaaata gagttggcta
    10141 tcactgcacc aagtggtata gttcccttca aataaaatga cataagcaca atttgtatcc
    10201 cacaacctgg aataagtcca agacctgcac ctataaatac acttattaca cctgttgata
    10261 atactaattt aactaagtat tcatctccac ctaaaattaa tattatcaaa tcgtaaataa
    10321 gatatgcaat aaaaatccat gtaattacaa atgatatttc tccaacagaa tggataagca
    10381 tttctcgcaa agaaatcttt ttattttctt cctctttttg attagaattt ttaaatacct
    10441 ttttaaaaca ccacatataa attattgaaa ataatattcc aatcactgct attacttctt
    10501 ccaatgaatg taacttctca attataggaa gattaagtcc agagtgagca agtgacataa
    10561 atataaaacc gattactata attcctatat aaattttata tccctttcca tgtgttatta
    10621 taaatgcaag tctatttgta tttccatgag atttagctag agtgtctaaa attatttcat
    10681 catgattatg ttgttcttta ttttctttag ggttattttt acttatatca tatttatctg
    10741 attttctacg gttttttaac cctaattttt cttctagttt aaagtaatcc actaattgtc
    10801 cagttattat tcctgtaatt gtactaacta tagtgacaaa aaaatacatt ttaatatttg
    10861 atgaaataag tacaaatgct gcatctccca tactagctat taaacttgca attattgctc
    10921 caaagcttaa ttttccattt atatacaatg gcattattgc caaacttccg ccacaacctg
    10981 gtatagctcc aattaaagca cctattaagg gttgaaattt tctgtttttt gatatgatat
    11041 tagtaaaatt tccactagtt ttataattaa tatatccaaa taacaaaata aaaaatccaa
    11101 tcatagaacc tacatgtaaa aacgcctctt cagaagcgga tatcaacatt tccattaatt
    11161 tacctcctag actaattttg caacaattat attatattct attttctatt gataatcaat
    11221 atcaatattt cttttgaatt tctaatatta aaaagtgcgc atcttatact cttagttttt
    11281 catcttaaga tacacacttt ttgatattag gttatctatt taccacatgt aatatgaaat
    11341 caaaggtgga tattatgata aattataaca atgtccacct atttttatta cctatcaaat
    11401 tataaatttt caaggaatgt tacaacttct tctattatcc aattaggtgt agatgcccct
    11461 gctgtaatac ccaaattttt atatttttta agcgtattta catccaattc atctttagtc
    11521 tctattgcaa aagttggtac taagtcttca caaaccttta ctaacttttg agtatttgaa
    11581 ctgtgtttac ctcctataac tatcatacaa tcaacttttt tagctaactc tttagctgat
    11641 tcttgtcttg tttttgtagc tgaacaaatt gtatcattaa atactatttc ttctaattta
    11701 tctgatagtt tattaactat acttatatac aactctggat ttattgtagt ctgtgcaaca
    11761 agacaatatc ttttggagtt atcaaattcc atattttcca tttgttctaa ggtctttatt
    11821 attatagctg aattttcaca ccatccattt atacctataa cttctggatg cttcatatct
    11881 ccaataacta ttatttcata gcctttatta tgatattcac ttactactgt atgtattttc
    11941 tttacaaatg gacatgtagt atccacaatt tttaattttt tatctttggc ttccttatat
    12001 atattttcag gaactccatg agaccttatt atcatatttt catgatttgg tattgtatca
    12061 atttcattca cagtcttaag acctttttct tcatattttg ctactgcttg cttgttatga
    12121 ataagaggac ctaaagcata tatgccagaa tcattttttt caacttcatc ccatgccatt
    12181 ttcattgctc tttttactcc aaaacaaaag ccagcatttt ttgctatttt tatgttcata
    12241 actttacccc cttattttga atatttaaag taattttgtt ttatcacttc taaaatctct
    12301 tgtgatatcc tttcatggtc atcattactc aatttttcct taaaatgttc ttcaaatgat
    12361 attggttctc caatatatac aattacttta ctaaaaagtt tatatttaga tattattgat
    12421 actggaacaa ctttagattt actttttatt gtaaatacag aaagacctgc cttagcctta
    12481 ccaaaagaat ctccttttat tctagtaccc tctggaaata ttcctaatac ataaccgtct
    12541 ctaactgacc ttaaaatagt ttttattgta gatacatctg gtttttctct atttataggc
    12601 ataacatgca atttttttaa tataaatccc aatggtttta ctttaaacaa ttctttcttt
    12661 gcaattgcag ctatttctct attttctatg gcagcagcca agaatatagg gtcaagattc
    12721 gatttatgat ttgatgctat tactatattt cctctatctg gaatattctc tgcacctata
    12781 acttcatatt taaaaaatat tttagaaaaa cccttaaaaa tatttattac aaatctataa
    12841 aaattcacgt ttatctccct tcaacactac atttattttc attatgatgc ataaaaaact
    12901 aaagatttat tttagataca acttcttcta caacttcttc tatagttttt cctgtagtat
    12961 ctatttctag tgcatcatta gcttttacca atggtgcaaa ttctctattt gaatcaattt
    13021 catctcgtct tattatatcc tcaattactt cttctaaagt agtattatat cctttattac
    13081 aaagttcttt atagcgtcta tttcctcttt cttctggagt agctactaaa aagaatttgt
    13141 aatctgcatc tgggaaaaca tatgaaccta tatctctacc atctagtatt actgaatttt
    13201 tcattcctat ttttcgttga acttcaacca tcaactgtct tacttctttt atttttgcta
    13261 cattagaaac attattgctt acttctattg ttcttatttc ttcatttata acttctttgt
    13321 ccaaatatat attgttatct ttaaaatcta tatccgaatt ttcagctatt tgaataactt
    13381 ctttttcatt attgacatca ataccacttt ttaaacactt ataagtaact gctctgtaca
    13441 tagcacctgt atctatataa tttatattta gcttttttgc tactatcttg gctattgtac
    13501 tttttccagc tcctgctgga ccatctacag ctataactaa attacccata tatacacctc
    13561 tatttattca tatttaatta ttaaaaaatt atatttatac acttataccc gcaagatatc
    13621 cagttgaaaa tgctatttgt aaattatatc caccagtttc tgcatctata tcaattactt
    13681 cacctgtaaa aaataagttc ttaactaatt tagattccat agtagaagaa ttaatttctt
    13741 taactgaaat accaccagaa gtaaccatac cagtgtttat acctgtagtc ccattacaag
    13801 ttagcttcat attttttata tactcaataa ttctaatttc atctgcctta gacaaatcac
    13861 ttgccttttt atcaactaaa gataatagag aaaaaatctc ttttaagaaa ttttgaggta
    13921 gtatttgctt aagattattt agaacatttt tatttggaaa tgctctgatt atactagaga
    13981 tttcatcagt acttaaattt ggtaagaaat ctatatttaa ttctaccttt tccttttcaa
    14041 taatcttgtt aatataagaa gacattataa gaacacaagg tcctgttatc ccaaaatggg
    14101 caaatagcat gtctccagat tttgatattt tccttttctt aatcttacaa gatatttcca
    14161 cattcttcat ggatattcct tgtaaatctt taatccattt ttcctctatt gtaagtggaa
    14221 ctaaagcagg atatagtttg tttaatgtat gtccatgctt tttaagaatc ttatacattg
    14281 aaccatctga acccgtcttt gaataactca ctcctccagt tgatataata accttgtctc
    14341 ctagtatttt atctccatta tctaaaataa tcccttttat tagatacttt gacttgtcct
    14401 tattagaatc atcttttaga gcaatttctt cagttataat atctataact ttcttattat
    14461 acattatctt tacattgtga ttgagtaaat ctttatttaa tacttctatt acttctatag
    14521 atttatcatt tttagtgtat actttgtggt cattttcttc ttcaatctta tattccaaat
    14581 ttctactttc aaaatacgaa ataaggtctt tatttgtaaa tgtatagaaa ctactataga
    14641 gaaatttttt attactgaca actttatcaa aaaaatcttc tatctctcta ttattggtaa
    14701 aattgcatct accgccacca gttgccctaa gttttcttcc taattctcca tttctctcaa
    14761 ctaatattac ttcattattg ttttttgaag ctgacaaagc tgccatcatt ccagaagctc
    14821 ctccaccaac tactataact ttactcataa atttctcctt ataattgatt cctactccag
    14881 tgcagaatta tttatcttta catgattttt tatatgactt gtatcattca tttttactat
    14941 aacaggccca taatctttaa attctactat atttaaagca gtattatctt gcttaattct
    15001 atatatattt tccatacctg attctaaaaa tgacaacaac ataaccctca atgtaattga
    15061 atgtgtaaca agaattatat ttttattatc atatttttca tttagttcct ttataaaagc
    15121 atctactctt tcctttataa tcttaagagt ttcgccttct ggtatattta ctaagtgtgg
    15181 ttcatttctc catgttgcat atatatctga ataatctttt tgaatttctt ttattaaaag
    15241 gccttcccaa actccgaatc ccatttctct aagtgcctca gttttttgaa cttcaatatt
    15301 gagcttatct cctaaaattt gagctgtttg cattgctctc ccaaggtcgc tactaaaaat
    15361 ataatcaatt gaatacttgc caatatcttc agaaagttct tttgcctgtt ctataccttg
    15421 aggcgtaagg tcagaattac catgaccttg tgtttttccc aatatattcc aatccgtttg
    15481 tccatgtctt actatataaa aagtatttcc catatgtcct cctaatatat gcctattttt
    15541 tattaaatat aaattatcac ttctcaaaac ttaattatat catataatac tttactttgt
    15601 ttctatttta taatctaatc taacatatta tttacaataa atctcatttg tatttctgca
    15661 aattattgta ctgttaaaga atttttctaa atttataaac atatttctct tatattattt
    15721 atatacttct tcaaatctgt attcttgaat tgaattgaca tacttatctg tatctacttt
    15781 ttctaaaaac atatccaaag gtcttgcaaa tattcctgta tcatcatata aggtcttgta
    15841 taaaactaaa tcattagtat cttcttcttt tttatgataa aagtttccat ctaaatccct
    15901 ataaacatag atatcttctt ctctttcagt atgtctaata actaatttat atttatttct
    15961 gttttggatt aaattttctt taccatatat ttcacatatg ttttctatat gatcaatagc
    16021 cttgctaaga cccattgtag cataatattt ccctttgaaa tgtttataga tacaaggata
    16081 ttttaacttt ctttcactga tacctaagtt attctttaat tcaagcattt tattataatc
    16141 tcccatatct cgtccctttc ttttaaaaag tattttattc tgaaataagt tacttgtttt
    16201 atattttatc ataatttaaa atttattaat aatacaatca ataaataaag aggctgtata
    16261 aaatacagcc tcccaatatt aatcttcata atcatataat ttttctaatt tcttttttaa
    16321 tttctttttt ctttctgaac ctaaaattct tataaaatta ttattcacaa aaatacaatt
    16381 attgctgaga taaaattcac acttgtctag atttacaata taactattac tgcatttgaa
    16441 aaaattttct tctttcaata gttttcttat acaaggagca ttttctccaa cttcataatt
    16501 accactttca gtataaatct ttacttcata ctcttgcttt tctatgtaca aaacttcttt
    16561 actattaatt gaaaaacgtt tatcctcgta ttcaacatta ataaaatttt cctctttcat
    16621 ttccatccct ccaagtactt ttattaattt aattttagtg ttttttatca atataatcta
    16681 tcggaaatat atgtaagact gatttactta agat
//
LOCUS       DAJMZY010000088        16586 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.088, whole genome shotgun sequence.
ACCESSION   DAJMZY010000088 DAJMZY010000000
VERSION     DAJMZY010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16586)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16586)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16586
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.088"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            603..1310
                     /locus_tag="OE968_002798"
     CDS             603..1310
                     /locus_tag="OE968_002798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HCP7220066.1"
                     /translation="MIFTKSNKYDKDFLMKNMMGPNCIKILEELTSKIKLEKGMRILD
                     LGCGKGISSIFLAKEFDATVFATDLWIEPTENYKRFKEFKLDDKIFPIQAEAHELPYA
                     EGFFDAVISIDSYHYFGNKEGFLDNHISPLVKEGGILAMAMPGLKEDFVDCIPDELIP
                     FWQDNMNFHSITWWNKLWSESESVIVEKCEALNCHDEAWKDWINCDNSYAINDKKMME
                     VENGKYFNTISLIARTK"
     gene            1909..2409
                     /locus_tag="OE968_002799"
     CDS             1909..2409
                     /locus_tag="OE968_002799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCP7220067.1"
                     /translation="MIEGIKFIKAEEKYIYSYWQTFDKIAKERKYLAMDEAFPFEETV
                     EFIKNIINKNLPQLFIIDLESDNCIGWCDVLPKTEKVGYLGMGILKEYREKGIGSNLL
                     KQIIDLSKEYGYEKIELDVFKSNSRAIHVYKSLGFVEVNTISSGFTWNDRPVKEEVIQ
                     MELTLI"
     gene            complement(2659..3438)
                     /locus_tag="OE968_002800"
     CDS             complement(2659..3438)
                     /locus_tag="OE968_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220068.1"
                     /translation="MNKNILNNSFPEVPESFHNSLSKTLNSLPEREENYKMINNKTHK
                     LPFRKGLVATLAITLILSTTALAVGHIYSLVGKSSTKATYTSIPTTEQVKKDFNFTPN
                     IVSEFSNGYKFKGAYTVNKKAFDKENNVLGKSKALSFEYKNGNDEISLDTANNVLGKS
                     SDNLKVVDTYKDINISYEAFAQKFVPEGYKMTEQDKIDEKSGKYTFSVGPNNESDKVE
                     VNKFKFLTWKQDGVYYSFTVQDSNLSMNDLVKMAHEVIDAK"
     gene            complement(3435..3914)
                     /locus_tag="OE968_002801"
     CDS             complement(3435..3914)
                     /locus_tag="OE968_002801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HCP7220069.1"
                     /translation="MDKTTFTNNILESEQTLYRVSKSILGNDQDCEDAVNNAILKAYE
                     KLDSLKEEQYFKTWLIRIVINECNSLRRKRLKSLSFEDVFKNKKIDEKDDYSDLYTAI
                     QSLPKKIKIPIVLYYIEGYSVDEVKEILDIPQGTVKSRLSRGRRLLKTKLENTEVII"
     gene            4900..5907
                     /locus_tag="OE968_002802"
     CDS             4900..5907
                     /locus_tag="OE968_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HCP7220070.1"
                     /translation="MGKYQDSKKVVRNYFEALENATGDEVENVLKQHMKSDYNWKGVY
                     PFREQEGTENVADVFWKPLKKSLSNMQRRQDIFIAGTNEIDNSEWVMSMGHFMGLFDN
                     DWLGIKHTRKMISLRYAEFNCVQDGKIAKTGLFVDIIGFMIQAGVNPLPPQTGSYFVY
                     PGPIDHNGLLFEDADEVEGVKTLALVNKMVDDLSELNESGAMGCPPEILEKSWAKDMI
                     WYGPGGIGASYTIPRYQEQHQLPFRNNLKGKTFNGHVCRFAEGNFACFFGWPNLTNVP
                     CGGFLGLPGGEVKADMQVVDVYYRKGDKLQENWVLIDIPYWLKQQGLDILERTKSIFN
                     A"
     gene            5945..7372
                     /locus_tag="OE968_002803"
     CDS             5945..7372
                     /locus_tag="OE968_002803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ester cyclase"
                     /protein_id="HCP7220071.1"
                     /translation="MASTNKNNATSKEEEKEVSTSGLESCTVKENKAKMNQTNFSNIN
                     ENQTNENKTNTYKRNIDKGNIDKGNIDKTNTNKSDINKVNIDTVDTDKLNTNTLTKKN
                     KKVIFKGEDNMSSTKIYYGDSLEVTPVGVMDYNDFSKQTKREQEIPGFDSKYRDFVDY
                     IMKITHNIWEEKGIGVIYDTYHNNVTMHCGSSNLVGIKDVISNTLQTLHAFPDRRLIG
                     QNVIWSNFGADGFLSSHRVLSTATNLGDSNFGPATGRKINFRTVIDCATTNNRIHEEW
                     LVRDNLWIVTQLGLNPQEVAKSMAKASESKVLSLQSTYGICESMDGQFMPTKYQAKDD
                     SAGEMMLEMTSRIYNYKYINEVKKYYHDNAVVHFICDKDLNGYDEIQGMIVSLLASIP
                     NGSYEVERVTCNQREKNEGYDVSVRWRLRGINEGIGFFGQPSGKHIEVMGINHYHILQ
                     GKVKEEWITFDGMDVLKQMYMGVEE"
     gene            7514..8779
                     /locus_tag="OE968_002804"
     CDS             7514..8779
                     /locus_tag="OE968_002804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCP7220072.1"
                     /translation="MKTTVEIENDIILGKDYSNLKRGIAFFSIALIYFFYCYNFMVGT
                     FIKPTMIYALADGGFGFSLKQTEEIFAVMSFGTIPGTFIFGVISTKIGKKRTLISVAL
                     LIGLTTFIPMLSPTNIMLWKIARLCTGVVLGGVFGTAMPLVADMFPSKYRGKLAAILT
                     ALFSLAMIFGGKVYGVLGDANWQILMYTAIIPPIVGAILAIFFVPDDLEYTKELVKKG
                     KETGEKISYISMYKGKYLWIGLGTILLSGANFTAYSAFSNNATTYLVTRIGMSAAVAG
                     SIYSLQGIGQLVGYLFWGSIADKFGRKIPFIGMALAAVFVFIYTKLGGDNTTTFYMIS
                     VLLGVAVGYSGAWGAYYTELFPSKYRSLSSGMSFNGGRIISTFAIPAIAGTASGTLGM
                     MTIFYISIAVFVAGAIVWLFLPETLNNKK"
     gene            8821..10419
                     /locus_tag="OE968_002805"
     CDS             8821..10419
                     /locus_tag="OE968_002805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter"
                     /protein_id="HCP7220073.1"
                     /translation="MISSIDVCIIIGYLLLMLVIGYYSGKDNKNQEDYFLAGRSMPWI
                     PIALSVAATMISANGFIGGPGWAYVDGMYPVMVNITVPLAIFFALSITTPVIYKLKIT
                     SIYEYMGLRLGNYSRGLTIIQFFINSLIQASSMVYIPVLIIQMITGWSLYALVPIVVL
                     VSIIYTLLGGIKAVIWTDSIQMIVVISAVFIVIIVALKGMNLSFFDTLQIAQQSGKLN
                     TFDFSRDISVTNTFWATLIGGTVMWIRYFCFDQSQVQRVLTSKSLKCAKNSFVVSAFV
                     MNLVYYFMLLVGVILFVFYGGRTFETSNEIMITFILNELPVGAIGIIIAGVFAAAMSS
                     IDSILNSMTTVFTKDIYEFYFKKDNKESSLKVTMIITVVIGVVMTGFIIMGFGGSIKS
                     ILDLVGNYISYFAGPATGAFVLAMFTYKANDKGVSIGFIVGLVLGFFISNKYNVSWLW
                     NPAIGATITLIFGYIFSVILKKNHNADDIKKYTAFGMRNHLISQGMDKVDGVSIVPFS
                     LGKQELIVLAFFIIQYIILFLIQF"
     gene            10454..11476
                     /locus_tag="OE968_002806"
     CDS             10454..11476
                     /locus_tag="OE968_002806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCP7220074.1"
                     /translation="MNQKKVHYNKSATSKDVARLAGVSQSSVSRAFGSANGKGVKPEV
                     RERIFRVANEIGYVPNLVARGMISGKTNVIGLIVGDSLGPFYNRIINLFVEKIQEIGK
                     QCLVFKVPRQQSIDSIISKVIQFQVEAVIITASAMNKVMAETCEENNIPVILFNRFIP
                     GIKISTVYVDPIEGGGMAAEYLLKKGHKNIGYIQFTRETSEEMEKKIGFYSKLRQSGI
                     HNLKEESANYDYDSGYEAGKRMLALSNPPTAIFCTSDLIAIGVMDAARFEYKLRVPED
                     LSVIGYDDIQMASWKSYNLTTIRQPLDLLIEKTINILKSLLNEENPESVVEMLKPELI
                     ERGSTL"
     gene            complement(11864..13267)
                     /locus_tag="OE968_002807"
     CDS             complement(11864..13267)
                     /locus_tag="OE968_002807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HCP7220075.1"
                     /translation="MKMLNNFFKKINNPAPVFAQTKMERDNQTDDSLSTKPKTTFRDV
                     AGLDEVKEELFEIVDFMKSPQKYQKMGAKIPKGVLFYGPPGTGKTLLASAVAGETNSS
                     FFNVTGSEFVEKYVGVGAKRVRTLFEKARKEAPSIIFIDEIDAVGAKRHLESNNEKDQ
                     TLNQLLVEMDGFNKDSNVLIIGATNRLDLLDEALLRPGRFDRHIHIGAPNYHTRFEIL
                     KVHTDDKPIDKSVNLELLAKKTHGFNGAHLSNIANEAAIFAVRDDSECITSEHFDKAL
                     ERVIAGLESKNSALVEKEKKIVAYHEAGHALVSDIVGICPIQKISIVPRGQALGYVLQ
                     LPDEDRYIYTKDELIGKIKILLAGKASEELIFNHKSTGAKDDLKKVTEIANQMVCEYG
                     MSNLGFMTIDGNDKTFLCDKVQKEANRIVEICYKETLEMLKDNLEDLHSVSKFLFEKE
                     TMTHEELKDLIGKEAVN"
     gene            14134..14643
                     /locus_tag="OE968_002808"
     CDS             14134..14643
                     /locus_tag="OE968_002808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HCP7220076.1"
                     /translation="MSKELAINEQIKDKEIRVLSPTGEQLGVMPTKEAQAMANSKNLD
                     LVQISSNANPPVCKIMDYGKFRYEQARKEKEAKKKQKTIVVKEVRLRPGIEQNDLNTK
                     ANNAIKFLKKGDKVKVELRFRGRELGHKDIGKEVMLKFLDIIKEFGEPTKAPAFEGNN
                     MVVIIDPKK"
     gene            14671..14865
                     /gene="rpmI"
                     /locus_tag="OE968_002809"
     CDS             14671..14865
                     /gene="rpmI"
                     /locus_tag="OE968_002809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011721840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HCP7220077.1"
                     /translation="MPKMKTHRGAAKRLKKTGTGKLKRAKAFKKHILTKKSAKTKMNL
                     RKSTLVSDGDAKRIAQLLPY"
     gene            14921..15277
                     /gene="rplT"
                     /locus_tag="OE968_002810"
     CDS             14921..15277
                     /gene="rplT"
                     /locus_tag="OE968_002810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HCP7220078.1"
                     /translation="MARVKKAMNARKKHKKILKLAKGFRGSRSKLYRPANTFVMKALK
                     NAYIGRKLKKRDFRKLWIQRINAAARMNGISYSRLMNGLKLSGIEVNRKMLSEMAIQD
                     PEGFAKLAEVAKAKLA"
     gene            15587..16132
                     /locus_tag="OE968_002811"
     CDS             15587..16132
                     /locus_tag="OE968_002811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220079.1"
                     /translation="MNEKLMDCFVNPIKCKLLIEIFSNNRTTAKQLGEKFQDISKATL
                     YRYLNKMLKDDIIKVVEENKIRGTVEKVYAMKLDIADDVNKIIDENSGEEYAQLFTQY
                     MMGFLREFYEYAERKEKDILKDGSGFSVCPVYASIDEIVEVSKKIASILEPLRNNSHE
                     EGRRMHSIGVIITPPKEDEGK"
     gene            16119..16283
                     /locus_tag="OE968_002812"
     CDS             16119..16283
                     /locus_tag="OE968_002812"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220080.1"
                     /translation="MKGNKSDLHEVEPIYTENRFMIYICIQSKVSLLGLYFIVSFHLS
                     NDLEWYNEVF"
BASE COUNT         6171 a         1868 c         2841 g         5706 t
ORIGIN      
        1 tttaaaaaaa tagaattatt atatttatga taataaatgg tataataaaa ggtaaagtgt
       61 caaatatgca ctaaattaaa taagttaatt agtatatagg ttaaagtgga agtaattaaa
      121 acttattaag tattagaaaa tgacttctta ttagagtaag tatctaaaat gatataaaaa
      181 ttatgattac tcattaaagt gactattata gagtggataa gattactcat taaagcgatt
      241 actgtggagt agataaaatt actcactaaa ataactatca tagagtggat aagattactc
      301 attaaagcga ttactgtaga gtagataaaa ttactcacta aaataattat catagagtgg
      361 ataagattac tcattaaagc gattgctgtg gagtagataa aattactcac taaaataact
      421 atcacagtag ataagattat tcattaaagt tactatcaca gagtggataa aattacacat
      481 taaaattgtc tgttaaagaa tgaataaaaa agagattgct caatataaga agcatataaa
      541 aaataaaaaa tcaaacgtat aaaatttaat aaataataac tgatagggaa aggaaagata
      601 gaatgatatt tacaaaaagt aataaatacg ataaggactt tctcatgaaa aatatgatgg
      661 gacctaattg tataaaaata ttggaagaat taacaagtaa gataaaacta gaaaagggaa
      721 tgcgtatttt agacttaggt tgtggtaaag gtatatcttc gatattttta gcaaaggaat
      781 ttgatgctac tgtatttgca acagatttat ggatagaacc aactgaaaac tataaaagat
      841 ttaaagagtt taaattggat gataaaatat ttccaataca ggcagaggca catgaactac
      901 cttatgcaga aggtttcttt gatgcggtga taagtatcga ttcttatcac tattttggaa
      961 acaaagaagg atttttagac aatcatatat cacctcttgt aaaagagggg ggaatacttg
     1021 ctatggcaat gcctggatta aaagaagatt tcgtggattg tataccagat gaactcattc
     1081 cattttggca agataatatg aacttccatt caattacatg gtggaataaa ctttggtctg
     1141 aatcggagtc tgtgattgta gagaaatgtg aagctttaaa ttgtcatgat gaagcttgga
     1201 aggattggat aaattgtgat aattcatatg ctataaatga caaaaaaatg atggaagtag
     1261 agaatggaaa gtattttaat acaatttctt tgatagcgag aactaaataa ttgtgatgaa
     1321 tttataaaag tataagataa gtagaaatat aagttgaatg agagtataag aagcatagaa
     1381 atataagttg aattaaagta gaaggtaaat aaaaatgtaa gttaaataaa gagtttatac
     1441 aaaaatgatt ttttagatta tttataccca atcgagttgc ttaggtcagt tgggtatttt
     1501 tattttttaa agttaaattg caaatactat tgtgtgatat atattttaat actaaatgtt
     1561 tgttttataa gaaataaact aatagaaaaa atagttttaa caatgaaagc aaaaaaggta
     1621 ttgatgaaga ttaaaaattt tatagtacca ttttatatat tttattatac tttaaatcaa
     1681 atttcaaaat gattaagtat atatacccaa aagattaaag aactatattt attatactat
     1741 taaaaattat tttaatagag atacaagaga tagatatatt ggttttaatt ttatagaaat
     1801 atacaaagat attttaagct aatatatagt aatttatata gcattataaa atagaatcat
     1861 ataaaataag ttaactacaa tcaaaaatta aaaaggggaa atgttaagtt gatagaaggc
     1921 ataaaattta taaaggcaga agaaaagtat atttattcgt attggcaaac ttttgataaa
     1981 atagcaaaag agaggaaata tctagctatg gatgaagcct ttccttttga agaaacagtt
     2041 gaatttataa aaaatattat aaataaaaac ttaccacaac tgtttataat tgatttagaa
     2101 tcagataact gtattggttg gtgtgacgtt ttacctaaaa ctgaaaaagt tggttattta
     2161 ggcatgggta ttcttaaaga gtatagggaa aaaggtatcg gaagtaatct tttaaaacaa
     2221 attattgatt tatcaaaaga atatgggtat gaaaaaattg agcttgatgt atttaaaagt
     2281 aatagtagag ctattcatgt ttataaatct ttagggtttg tagaggtaaa tacaatatct
     2341 agtggtttta catggaatga tagacctgta aaagaagaag taattcaaat ggagcttaca
     2401 cttatataaa ataaagttaa agtctttaaa attccatata cacttgtata aaataaagtt
     2461 aaagccctta aaattccata taaaagaaat atttttaagg gctttttaat aatgcttctt
     2521 ttgaaggtag ctaaatatct aaaattttat atattaaatt taaagaaaat ataaagatgg
     2581 aagatacaac catgtttact aataaaaaaa ttaaagtcat aaataataaa ctcataaaca
     2641 acttattatt acttatgttt attttgcatc tattacttca tgagccattt taactaagtc
     2701 attcatagat aaatttgagt cttgaactgt aaaagaatag taaactccat cttgtttcca
     2761 tgtcaaaaac ttaaatttat taacttcaac tttgtctgat tcattatttg gccctacact
     2821 aaatgtgtat ttgcctgatt tttcatcaat tttatcctgt tctgtcattt tataaccttc
     2881 tggtacaaac ttttgtgcga atgcttcata agaaatatta atatctttgt aagtatctac
     2941 aacttttaga ttgtcagaac tcttcccaag tacattattt gctgtgtcaa gagatatttc
     3001 atcattgcca tttttatatt caaaactaag tgcttttgat tttcctaaaa cattattttc
     3061 tttgtcaaat gcttttttat ttacagtata tgctccttta aatttatatc cattactaaa
     3121 ttcagaaact atattagggg taaagttaaa gtcttttttt acttgttctg tagttgggat
     3181 agatgtatag gtagccttag tacttgattt tccaaccaaa ctatatatat gtcctactgc
     3241 aagggctgtt gtgctcaata tcaaagtaat ggctaaagtt gcaactaagc cttttctaaa
     3301 tggtaatttg tgtgttttat tattaatcat tttataattt tcctctcttt ctggtaaact
     3361 atttagtgtt ttgcttaaac tattatgaaa actttctgga acttctggaa acgaattatt
     3421 taatatattt ttattcatat gattacctcc gtgttttcta atttagtttt taataatctt
     3481 cttcctcttg ataatctact ttttacagtt ccttgaggta tatctaatat ttccttaact
     3541 tcatctactg aataaccttc aatatagtaa aggactattg gaattttaat ttttttaggt
     3601 agactttgaa tagcagtata caaatcgcta tagtcatctt tttcatcaat ttttttgttt
     3661 ttgaagacat cttcaaatga tagagatttt aatcgtttgc gtcttaatga attacattca
     3721 tttatgacta ttctaatcag ccatgtttta aagtattgtt cttccttaag agaatccaac
     3781 ttttcatatg cttttaaaat agcattgttg acggcatctt cacagtcttg gtcgtttcct
     3841 agaatagact tagatactcg atacaaagtc tgttctgatt caagtatatt gtttgtaaat
     3901 gtagttttat ccaactaagt tccttccctt ctatgcaaat cgtagcgcta cttttttgtc
     3961 tttcacttat tagataaaat tttactatag atggttcact ttttttatga ttatttgata
     4021 aatttaagtt tgaaagtttt gcctattcta tacaaatatt ctataatata ttttttctag
     4081 tattttcccc tcatatataa agccatgtag atatattaaa ctttagaagc catttatata
     4141 tttagtttta tagtaagtct ttatattgag taattagaaa atagtaagta tttaatgttg
     4201 agtagttaga ataacaatgc ttttggatta tttacttcat gtacagattt aaaataagtt
     4261 ctttaaatag caactttttg aaaaaacgca aaaatatttt atgttgtctg attatattta
     4321 tagatgtgaa acaatattgt atagagtaaa agtatataga agatgattac atagagttta
     4381 tacttgaatt ttacaaatat aattatcaaa atactgtcaa agagaaaaat agttttgatg
     4441 aacgttttta tcaaattgct acagagacag ggctaagtgc taatactgta tataaagtat
     4501 tcaataaaat aataaatagt ggaaaaactg aatttacatc aaaggaatta gctactatat
     4561 gtggtgtaag tattagaact atggacagga ttatacttag attgtgtgat tctggttatt
     4621 gtgaggtagt gagtgaacag cttatgagca agtatggtag acccagtaga atattacgtt
     4681 ttaaaccttt tctgttgttt taaatagata taagtcaaaa attaaatttt tatgataaca
     4741 ttttctttac aattttttag atatatgtta atatttagaa aaatgcatat gtattcataa
     4801 aataaactta aaacagctaa aaaatcatta aaaaggaaat tgtatgcatg aaatgagaaa
     4861 gttaatttat aacttaaata aatctgggag gagataatta tgggaaaata tcaggattca
     4921 aaaaaagttg taagaaatta ttttgaagca ttagaaaatg ctactgggga tgaggttgaa
     4981 aatgtcttaa agcaacatat gaaatcagat tataactgga aaggtgtgta tccatttcgt
     5041 gaacaagaag gcactgaaaa tgtagcagat gtattttgga agcctttaaa aaaatcattg
     5101 agtaatatgc aaagacgaca agatattttc attgcaggaa caaatgagat tgacaatagt
     5161 gaatgggtaa tgagtatggg gcattttatg ggactttttg ataacgattg gcttggcatt
     5221 aaacatactc gtaaaatgat tagtttaaga tatgcagaat ttaactgtgt tcaagatggt
     5281 aaaattgcta aaactggatt atttgtagat ataattgggt ttatgattca agcaggagtt
     5341 aatccattgc caccacaaac aggttcatat tttgtatatc cagggccaat tgaccataat
     5401 ggattacttt ttgaagatgc agatgaagtt gaaggagtaa aaactttagc attagtaaat
     5461 aaaatggtag atgatttatc tgaattaaat gaaagtggtg ctatgggatg cccaccagaa
     5521 atacttgaaa aatcttgggc taaagatatg atttggtatg gtccaggtgg aattggtgct
     5581 tcttatacta tacctagata tcaagagcaa caccagctac catttagaaa taatttaaaa
     5641 ggaaagactt tcaatgggca tgtatgtaga tttgcagaag gtaattttgc ttgtttcttt
     5701 ggatggccta atctgactaa tgtaccatgt ggaggttttt taggattacc aggtggagag
     5761 gttaaagcag atatgcaagt tgttgatgtt tattatcgta agggcgataa acttcaagaa
     5821 aactgggtgt taattgatat tccttattgg ttgaaacaac aagggcttga tattcttgag
     5881 agaactaaaa gtatttttaa tgcttagtta tgcatacgta ttctaaaata aagggggata
     5941 taaagtggca tctaccaaca aaaataatgc aacaagtaaa gaagaagaaa aagaagtttc
     6001 tacaagtggg cttgaatcat gtacggttaa agaaaacaaa gctaaaatga atcaaactaa
     6061 ttttagtaat ataaatgaaa atcaaacaaa tgagaataaa acgaacacat ataaaagaaa
     6121 tatagataaa ggaaatatag ataaagggaa tatagataaa acaaacacaa ataaatccga
     6181 cataaataaa gttaacatag atacagtgga tacagataaa ttaaatacaa atactcttac
     6241 taaaaaaaat aaaaaagtta tatttaaggg ggaagataat atgtcatcta caaaaattta
     6301 ctatggagat tcattagaag taacgcctgt tggagtaatg gattacaatg atttttcaaa
     6361 acagacaaaa agggaacagg aaatacctgg atttgattct aagtatagag attttgtaga
     6421 ttatattatg aagattacac ataatatctg ggaagaaaaa ggtataggtg ttatttatga
     6481 tacatatcac aataatgtta caatgcattg tggctcttca aatttagttg gtattaaaga
     6541 tgttatttcc aatactcttc aaacattaca tgcgtttcct gatagaagat taattggtca
     6601 aaatgtaata tggtctaact ttggtgctga tggtttttta tcttctcacc gtgttttgtc
     6661 tacagcaact aacttaggtg atagtaattt tggaccagca acaggtagaa aaataaactt
     6721 tagaactgta attgattgtg ccacaactaa caatagaatc cacgaagaat ggttggttag
     6781 agataattta tggattgtta ctcaattagg attaaaccct caggaagtag caaagagtat
     6841 ggcaaaggca agtgaatcta aagtgcttag tttacaatca acttatggta tctgtgaatc
     6901 tatggatggt caatttatgc caactaagta tcaagcaaaa gatgattctg ctggcgaaat
     6961 gatgcttgaa atgacaagcc gtatttataa ttataaatat ataaatgaag ttaaaaaata
     7021 ctatcatgat aatgcagtag tacattttat atgtgataaa gatttaaatg gttatgatga
     7081 gattcaagga atgattgtaa gtttacttgc atcaattcca aatggaagtt atgaagtgga
     7141 aagagtaact tgtaatcaaa gagaaaaaaa tgaaggttat gatgtatctg taagatggag
     7201 attacgtgga ataaatgaag gtataggatt ttttggacag ccttctggaa agcatataga
     7261 agtaatggga atcaatcatt atcatatact acaaggtaaa gtaaaggagg agtggataac
     7321 ttttgatggt atggatgtat taaaacaaat gtatatggga gtagaagaat aaagctgttt
     7381 agagtataaa tagttttgaa atatataggg aagtattgct ttataaaatt taagtgggga
     7441 atgtatatga aaaatagatg tttaaacttt tagcaaaatt atgactaaat ttaaaagggg
     7501 gaattataaa aatatgaaaa caacggttga aatagaaaat gatatcatat taggaaaaga
     7561 ctattcaaac ctaaaaagag gaattgcatt tttttcaatt gctttaatat acttttttta
     7621 ttgctacaat tttatggtgg gtacttttat taaaccaaca atgatttatg ctttagcaga
     7681 tgggggattt ggtttttcat taaaacaaac agaagaaata tttgcagtta tgtcttttgg
     7741 tacaattcca ggtacattta tttttggggt gatttctaca aaaattggga agaagaggac
     7801 tttaattagc gttgctttac tgattggatt gacaacattt ataccaatgt tatctcctac
     7861 aaatattatg ttatggaaaa tagcacgttt gtgtacagga gtagtgttgg gaggcgtatt
     7921 tggaacagct atgcctttag ttgcagatat gtttccaagt aaatatcgtg gtaagttagc
     7981 tgctatatta actgctttat tttcattagc aatgattttt ggtgggaaag tatatggcgt
     8041 tttaggtgat gcaaattggc aaatattgat gtatactgcg attataccac ctatagttgg
     8101 agctatctta gcaattttct ttgtgccaga tgatttggag tatacaaagg aattagttaa
     8161 aaagggaaaa gaaactggtg aaaagattag ctatataagt atgtataagg gaaaatactt
     8221 atggattgga ttgggaacga ttcttttatc aggtgcaaat tttacagcat attcagcatt
     8281 ttcaaataat gcaactacat acctagtgac aagaatagga atgtcagcag cagtggctgg
     8341 gtctatatat agtttacaag gaattggtca attagtagga tatttattct ggggttcaat
     8401 tgcagataaa tttggaagaa aaataccttt tataggtatg gcattagcag cagtatttgt
     8461 ttttatatat acaaaattag gtggagataa tacaacaaca ttctatatga tatcagtatt
     8521 actaggtgtt gctgttggat attctggagc atggggagca tactacacag agttgttccc
     8581 aagtaaatat cgttcgttgt catctggtat gtcatttaat ggaggaagga ttatatctac
     8641 gtttgcaata cctgctatag ctggtacagc ttctggtact ttaggtatga tgactatctt
     8701 ttacatatca atcgcagtct ttgtagcagg tgctattgta tggttattct taccggagac
     8761 gttaaataat aaaaaataaa atactaggaa tttattttgt tacttagaaa ggggtggctt
     8821 atgatttcat caattgatgt atgtattata ataggatatt tgctattaat gttagttatt
     8881 ggttattatt caggaaaaga taataaaaat caagaagatt atttcttggc aggtaggtca
     8941 atgccatgga ttccaattgc tttatcagtt gcagctacta tgattagtgc aaatggcttt
     9001 ataggtggtc ctggatgggc atatgtagat ggaatgtatc cagtaatggt taatattaca
     9061 gtacctttag caatattttt tgcactgagc attaccaccc cagttatcta taaattaaaa
     9121 ataacctcta tatatgaata tatgggactt cgtttaggaa attattcaag aggattaact
     9181 attattcaat tttttattaa ttcattgatt caagctagtt ctatggtata tattccagtg
     9241 cttattattc aaatgattac tggctggtca ctttatgctt tagtcccaat agttgtactt
     9301 gtatcaatta tatatactct attaggtggg attaaggcag ttatatggac tgatagtatt
     9361 caaatgatag tagtaataag tgctgtattt atagtaatta ttgtagcctt aaaaggaatg
     9421 aatctaagtt tctttgatac attacaaatt gcacaacaga gtggaaaatt aaatacattt
     9481 gatttcagta gggatatttc agtgacaaat actttttggg ctactttaat tggtggaact
     9541 gtaatgtgga taagatactt ttgttttgac caatctcaag tacaaagagt tttaacatct
     9601 aaatctttaa aatgtgcaaa aaattctttt gtagttagtg catttgttat gaatttagtt
     9661 tactacttta tgctattggt aggagtaatt ttatttgttt tttatggggg aaggacattt
     9721 gaaacttcaa atgaaataat gattactttt attttaaatg aacttccagt aggagccatt
     9781 ggaattatta ttgcaggtgt gtttgcagca gcaatgtcta gtatcgactc tatattaaac
     9841 agtatgacaa ctgtttttac gaaggatatt tatgagtttt atttcaaaaa agacaacaaa
     9901 gaatcatcat taaaagttac aatgattata actgtagtta taggagttgt tatgacaggt
     9961 tttattatta tgggatttgg aggaagcatc aaatcaattc ttgaccttgt tggtaactat
    10021 atctcatact ttgctggacc agctacaggt gcatttgtac tagcaatgtt tacatataaa
    10081 gctaatgata aaggagtatc tattggtttt attgtagggt tagttttagg attttttatt
    10141 tctaataaat ataatgtgag ttggttgtgg aatccagcaa taggtgctac aataacattg
    10201 atatttggat atatttttag tgtcatttta aagaaaaatc ataatgcaga tgatattaaa
    10261 aaatacactg catttggtat gagaaatcac cttatttctc aaggaatgga taaagtagat
    10321 ggagtatcta tagtgccatt ttctttaggt aaacaagaac taattgtatt agcttttttt
    10381 attatccaat atattatatt atttttgata caattttaag aagaaatact agatatttaa
    10441 ggagaaatac taaatgaatc aaaagaaagt tcattataat aaatcggcta cctcaaaaga
    10501 tgttgcaaga ttggcaggag tatctcaatc atctgtttca agagcatttg gtagtgcaaa
    10561 tggaaagggc gtaaaacctg aagtaagaga aagaattttt cgtgtagcaa acgaaatagg
    10621 atatgttcct aatttggtag cacggggaat gattagtgga aaaactaatg ttataggatt
    10681 gatagttggt gatagtctag gtccatttta caatagaatt atcaatttat ttgtagaaaa
    10741 aattcaagag ataggtaaac agtgtctcgt ttttaaagtt cctagacaac aaagtataga
    10801 tagtataatt tcaaaagtaa ttcagtttca agtagaagct gtgattatta cagcttcggc
    10861 catgaataag gtgatggctg agacttgtga agaaaacaat attcctgtga ttctttttaa
    10921 tcgttttata cctggtataa aaataagtac agtctatgta gacccaattg aaggtggggg
    10981 aatggctgct gaatatctgc ttaagaaagg tcataagaat ataggatata ttcaatttac
    11041 gagagaaaca agtgaagaaa tggaaaagaa aattggattt tattctaagt taagacaaag
    11101 tgggattcat aaccttaaag aagaatctgc aaactatgat tatgattctg gatatgaagc
    11161 aggtaagaga atgttagcat tatcaaatcc tccaacagca attttttgca caagtgactt
    11221 gatagctatt ggtgtaatgg atgctgcaag gtttgagtac aagttgaggg tgccagagga
    11281 tttatcagtg ataggatatg atgatattca aatggcttca tggaagagtt ataatttaac
    11341 gacgattaga cagccactag atttgttgat tgaaaaaaca attaacatac ttaagtcctt
    11401 attaaatgaa gaaaatccag agtcagttgt tgaaatgtta aaacctgaat tgattgaaag
    11461 aggttctaca ctttaagtgg tagatattta attaagtggt agatacctaa ttaagttgta
    11521 gatatctgat aagaaatttt taagttttca atcgttctaa attgtgagta taaaaatcta
    11581 ctaaatttag ttatgtaaaa tataaattat aagtgtagaa actaggctac tagcttttat
    11641 accacttcaa acattactgg aggtagttaa gtttacatca gtttagtttt atgtagatat
    11701 aatattctgt aaatagacaa aattaaaata tgtaagtgtc tcaaaatgaa atttttagtt
    11761 tatgaggcac ttttttgtat aaaatcaaat gtatttttat aactttaaca ataaaaagag
    11821 gcttatctct attttgagac agcctcaaat ttttaaaact atattagttt acagcttctt
    11881 ttcctatcaa atcttttaac tcttcatgag tcatagtttc tttttcaaat aagaatttag
    11941 aaacagaatg taaatcttca agattatcct ttaacatctc taaagtctct ttataacaaa
    12001 tttcaactat acgatttgct tccttttgaa ccttatcaca taagaaagtc ttatcatttc
    12061 catcaatagt cataaatcct aagttactca taccatattc acaaaccatt tggttagcta
    12121 tttcagtgac tttctttaag tcgtcctttg caccagtaga tttatgatta aatattaatt
    12181 cttctgaagc ctttccagca agtaatattt ttatttttcc aatcaactca tccttagtat
    12241 aaatatatct atcttcatca ggtaattgaa gaacataacc taatgcttgt cctctaggaa
    12301 ctatagatat tttttgtata ggacaaattc ctactatatc acttacaaga gcatgtccag
    12361 cttcatgata tgctactatt tttttctctt tttcaaccaa tgcagagttt ttagattcta
    12421 gccctgcaat aactctttca agtgccttgt caaaatgttc tgatgtaata cactcactgt
    12481 catctctaac tgcaaatata gctgcttcat ttgctatatt tgaaagatga gccccattga
    12541 aaccatgagt ttttttagct aaaagttcta gatttacaga tttgtctata ggtttgtcat
    12601 ctgtatgtac ctttagaatt tcaaatctag tgtgatagtt tggtgcacct atatgaatgt
    12661 gtctgtcaaa tcttcctggt ctaagtaaag cttcatctaa taagtcaagt ctattggtag
    12721 cacctattat taatacattg gaatctttat taaatccatc catttcaact aaaagttggt
    12781 ttagtgtttg gtctttttcg ttgttacttt caagatgtct ctttgctcct acagcatcta
    12841 tttcgtctat aaatattata cttggagctt cttttctagc tttttcaaat agagttctaa
    12901 ctctttttgc tcccacacct acatattttt caacgaactc tgaaccagta acattgaaaa
    12961 atgatgagtt tgtttcacca gctacagcag atgcaagtag ggttttacct gttcctggag
    13021 gaccataaaa taatactcct ttaggtattt ttgcacccat tttttgatat ttttgtggtg
    13081 acttcataaa atcgactatt tcaaatagtt cttcttttac ttcatctaat ccagcaacat
    13141 ctctaaatgt agtctttggt tttgtagaaa gtgaatcatc tgtttgatta tctctttcca
    13201 tttttgtctg tgcaaagaca ggagctggat tgttgatttt cttaaaaaag ttgtttagca
    13261 ttttcatatt cacacctcag gtaattaatt attgttaatc aattttatat tttccatatt
    13321 tactattttt tattatttat ttttcatgga aaaaatatac atgttatcta aataaaaata
    13381 aatttgtaag atgtatgaaa aaatgaattt atgtatatag agatttctac ttatgtattg
    13441 aataaagtat tacaaattat aaattatgta ttgattatat attgagtaaa gtattataaa
    13501 gcatgtattg attaagtatt gaataaaata ttacaaattt agttgaaatg aaaatgataa
    13561 aaaatcttgt actatatttt acaaatcata taaatagaga aattgttgta gcacaaagta
    13621 gtaggtagta tattagaata taatatagga tttgttgtgt agtatagtag catattagaa
    13681 tataatatag gatttgttat gtagtatagt agtatattag aatacaatat agaatttgtt
    13741 gggtagtata gtgttatatt agaatacaat ataggatttg ttatgtagaa tatatagagt
    13801 catgtagaat ataaatatat aaaaggattt tgggtataaa tttaaaaatt aatagcaaaa
    13861 tgagtagtat agacatataa ttagtagtag gaagtaatta aatttttcct aaacaaaaaa
    13921 aatagttgca aataatttga ttaagtgata tagtagataa ggtaagaata aaacaaagaa
    13981 gaagtccgct tctcacctta cgccggaggt tagtaaggta aatataagtt aaagcttaat
    14041 tttaatttaa gtttgtttaa atttggtaac ttatattgcg gatgattacg tcatccgctt
    14101 tttattttat aaaaattttg gaggtgtcct acaattagca aagaattagc aatcaatgaa
    14161 caaataaaag ataaggaaat aagagtcctt tcaccaacag gtgaacaact tggagtaatg
    14221 cctactaaag aagctcaagc aatggctaat agcaaaaact tagatttggt tcaaatctcg
    14281 tcgaatgcaa atccaccagt atgtaagata atggattatg gaaagtttag atatgagcaa
    14341 gcgagaaaag agaaagaagc taagaaaaaa caaaaaacta tagttgtaaa agaagtaaga
    14401 cttagaccag gtattgaaca aaatgattta aatacgaaag ctaataatgc tataaagttc
    14461 cttaaaaaag gggataaagt caaagttgaa cttagattta gaggaagaga attaggacat
    14521 aaagacatag gtaaagaagt tatgcttaag tttttagata taataaaaga gtttggagaa
    14581 ccaacaaaag cccctgcatt tgagggtaat aatatggttg taattataga tccaaaaaaa
    14641 tagatgatta actgagagga ggaatttgtc atgcctaaaa tgaaaactca tagaggtgca
    14701 gcaaagagat taaagaaaac aggaactgga aagttaaaga gagctaaagc ttttaaaaaa
    14761 catatattaa ctaaaaaatc tgcaaaaact aaaatgaact taagaaaatc aactttagta
    14821 agtgatggag atgctaagag aatagcacaa ttattaccat actaagatac agattgtaaa
    14881 taataactat agaagaggga tataaaagga ggtcataacg atggcaagag ttaaaaaagc
    14941 tatgaacgct cgtaaaaagc ataagaaaat attaaaactt gcaaaaggat tcagaggatc
    15001 tagaagcaaa ttatatagac cagcaaatac attcgtaatg aaagcattaa aaaatgctta
    15061 tataggaaga aagttaaaga agagagactt cagaaaactt tggatacaaa gaataaatgc
    15121 agctgctaga atgaatggaa tatcttattc aagattaatg aatggattaa aattatctgg
    15181 tattgaagtt aacagaaaaa tgttatctga aatggctata caagacccag aaggatttgc
    15241 aaaattagca gaagttgcta aagcaaaatt agcttagtat tgaatcatga gatgtaaagt
    15301 ctttgagtta tataaataat tcaaggactt ttttattttt tgaaaaatac ttattagtgt
    15361 catgtacaac caattttata atgataaata aaataagcaa tacaatagaa ttttatgaga
    15421 tttattataa gaattgttac aattatttat gatagctata aaaagtcata gtaaaaatga
    15481 tattgatgta tgttgatata tgtataaagc tttcaatcaa tcttgaatta atattatcaa
    15541 catgataata ttatcttatt aataatataa ataaggggga gataatatga atgaaaaact
    15601 aatggattgt tttgtaaacc caattaaatg caagttattg attgaaattt tttcaaataa
    15661 tcgaactaca gctaaacaat taggagaaaa atttcaagat atatcaaagg caacacttta
    15721 tcgttacctt aataaaatgt tgaaagatga tattataaaa gtagttgaag aaaataaaat
    15781 aaggggaact gttgaaaaag tatatgctat gaagttagat atagctgatg atgtgaacaa
    15841 aattatagat gagaactctg gagaagaata tgctcaactg tttactcaat atatgatggg
    15901 atttttaaga gaattttatg aatacgctga aagaaaggaa aaggatatcc taaaagatgg
    15961 ttcaggattt tctgtctgtc cagtatatgc tagtattgat gagatagttg aagtgagtaa
    16021 aaaaattgct agtatactag aacctctaag aaataactcg cacgaagaag gcagaagaat
    16081 gcattctata ggagtgataa tcactccacc taaagaggat gaagggaaat aaatctgatt
    16141 tacatgaggt agagccaatt tacacggaaa atcgttttat gatttacata tgtatccaga
    16201 gcaaagtatc tctgcttgga ttgtacttca ttgtatcatt tcatctatct aatgacttgg
    16261 agtggtacaa tgaagttttt taatttttca tatcaatgcc taaagaaatg aactttagac
    16321 cacatatgca attaggttac attatacaat tagaccagat atacaaaata aaaatcagta
    16381 tttttatagc agataaattg actgttattc ttcttaaaaa tcatctatta gttattgtta
    16441 gcatattgaa agaaattata ggaatctatt gaataaatga atattgccca taatcatata
    16501 aactgctata gtttaaaata aagcaggacg ttaaatttta tagtaatcta aaaatttaag
    16561 agggggattt tatgaaaata aaattt
//
LOCUS       DAJMZY010000089        16580 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.089, whole genome shotgun sequence.
ACCESSION   DAJMZY010000089 DAJMZY010000000
VERSION     DAJMZY010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16580)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16580)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16580
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.089"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            <1..766
                     /locus_tag="OE968_002813"
     CDS             <1..766
                     /locus_tag="OE968_002813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="cell wall-binding protein Cwp11"
                     /protein_id="HCP7220081.1"
                     /translation="AKNITSVGEINEKVIQQCINASNSNGQPPTITVGSTEVYKGEKF
                     DTGKLNIVAKDNTGKVLPIEVDGFIDTNRVGTYILTLKATDEWGKSTGKRVEIKVLDD
                     KSHDYNSPEFKKMVSTEMYNLINSYRKEKGKEPLLVSSRLEGMANAWSKYMMDKKVFA
                     HYIDGKNAPQVFSEFGMRSEENIAYIYIDSKNVQTTQDAKDLAKAIFEVWKKSPEYNA
                     NMLSNEFYSTGFGLYILSDGQVHATQEFLNGNEGSL"
     gene            985..2583
                     /locus_tag="OE968_002814"
     CDS             985..2583
                     /locus_tag="OE968_002814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HCP7220082.1"
                     /translation="MKVNKRVLSIGLTISLIMAGAPNINALSSIEKIQGKDRYETSAL
                     IADKQIYDTIILVNTDNSIVDGLSASGLSGVAKAPIMLVQRDKIPTDVEKRLKDVKNA
                     YVIGTEDTIGKSVENQLKNKGIEVKRIGGEDRIKTSYLIAKEISAIKPVNDGDKVFLV
                     NGYTGEADAMSVSSVAARDGVPVILTDGKSIPFKVDGVQCYSLGSEEIMSNELVSKTN
                     SVRIAGKDRFETNKKVIQRFYKGTKKFYVSQGYKLVDAVAGSPLAKDKPIVLVNDGSD
                     KSVLRGADEVTSLGGMDKKVVDQCISSASDKNTMPTITANDVEISVGDKFDNSMLNIV
                     ATDYYGNDLKANIKGNVDINKAGTYVLNISVVDNLGQKSEISVNVKVVVNASTKDSNS
                     YEFKAMVSNEMYDLVNSYRKEKGKKSLRELDSLAGMANAWSKYMEDKKVFAHEIDGKN
                     AAEVFFGFGARSGENIAYLPMNVKSVYTSKDAKEMAESIFDLWKKSSKYNENMLKEEF
                     YSFGFGMHVSSKGEVNATMEFLNS"
     gene            2873..5071
                     /gene="slpA"
                     /locus_tag="OE968_002815"
     CDS             2873..5071
                     /gene="slpA"
                     /locus_tag="OE968_002815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-layer protein SlpA"
                     /protein_id="HCP7220083.1"
                     /translation="MNKKNLAMAMAAVTVVGSAAPIFADTTVKEEGYTVVQDKYEKLL
                     KELKAKIKDGTITSVGVEFDGKPITTLAPKADGSDKDAIAEQLETLTKNQLKGLGDGK
                     YVDFKITYGAKAEVPAASLSADDIQKYADQINASEKILVEVAAGSEAGIAKFDSVNNK
                     VIAGDAPLKVKDAVKATVTTNGSNKKVLTISAAAGLSGFSYGTLKDTGASSSDVDAIT
                     LDTTNATITEGDTKVLDFDNSFKFNESTKKVGSLVTPNTTNTPADPGTKTTVRVIKAV
                     EKTIDVSSNSTTKAKDLAKQYVFTDVSDTDPESLSYMLKNINDGKVAVKNSDGDYEVT
                     IFPEGKRLNTLSASSAKTILGDKDTPAKIVLKASTTKKLADYIDDLITYNNSYSNVQT
                     VAGSDRIETAIELSRKYYNSTDKNALYGDPVNNVVLVGSQAIVDGLVASPLAAEKDAP
                     LLLSSKDKLDSSTRAEIKRVMDLNSSTGIKNNKEVFIAGGVNSISKDVENELKDMGLK
                     VTRLSGDDRYETSLAIADEIDINDKAYVVGGTGLADAMSIAPVASQIKDGEATPIVVV
                     DGKSDKLSKEAEDFLDDAQVDIIGGENSVSAKMEDYIDDATGKSPERISGADRQATNA
                     EVIKEYFDKDGVSNYFLAKDGSTKEDQLVDALAAAAVAGNYGSKHNEDGDITTDASPA
                     PIILATDNLSAEQHVAVSKTATTNGAKNLVQVGQGIADSVVSKLKDLLDM"
     gene            5317..7659
                     /gene="secA"
                     /locus_tag="OE968_002816"
     CDS             5317..7659
                     /gene="secA"
                     /locus_tag="OE968_002816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HCP7220084.1"
                     /translation="MSVLDVILDKTDELEIKKLNNIVDKIDALEDKIQILDDEALKNM
                     TNVFKDKLSKGETLDDILPEAFAVVREVSKRILGMRQYRVQLIGGIVLHQGKIAEMRT
                     GEGKTLVGVAPVYLNALTGKGVHVITVNDYLAQRDKELMQPVYEFLGLTVGVIINGQQ
                     PVERKLQYQCDITYGTNNEYGFDYLRDNMVTQKSEKVQRELNFAIVDEVDSILIDEAR
                     TPLIIAGGGDEGTKLYELANAFIKNIRDEDFEMDRKDKTIALTASGLSKAEKFFGIEN
                     ITHIDNIEIFHHVNQSLRAHKLMNIDVEYVVRDNEILIVDEFTGRIMDGRRFTDGLHQ
                     AIEAKEGVKINDESKTMATVTFQNFFRLYSKLSGMTGTAKTEESEFEATYKINVVQIP
                     TNKPVIRADLHDKVFKTERAKYNAVVEEIIRINKTKQPVLVGTVSIEKSEKLSKLLKK
                     KGVKHEVLNAKQHDKEAEIISKAGKLGSVTIATNMAGRGTDISLGAGDKEEEEKVKEL
                     GGLYVIGTERHETRRIDNQLRGRSGRQGDPGTSRFFVSLEDEVIKLYGGKSIEKILKR
                     MNANEDDALESKALNRAIERAQKGIEGKNFEQRKNVLKYDDTINEQRKVIYDERNKVL
                     DGSDIEEEIQKMVMDIITEAAEKYLKKFRDYHGYFKYLYNTFMPADTLLIPDLDKKNV
                     EEIVNQTYQISKRVYDLKKMMIGIEELAQLEKRVLLQVVDTYWVDHIDAMDQLRQYIG
                     LKSYAQKDPFKEYAIEGYEMFEALNRNIRITTVQYLYKFN"
     gene            8073..9944
                     /locus_tag="OE968_002817"
     CDS             8073..9944
                     /locus_tag="OE968_002817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HCP7220085.1"
                     /translation="MNRKNLYVIMAAAMVSTSVAPSFAAEATQVKKQTITKKEATELV
                     SKVRELMAQRYTGGSQVGQPIYEIKVGETSSQLKIITNIDELEKLVNALGENKELLVT
                     IADKGHTTNSANEVVAEAIEKYENSADLSAEANSITEKAKTEATGIYGVATVEASYDS
                     TKDKLVITLKDKTDVVTSKTLQIGIGDEKVDLTANPVDIAGTNLDPSAEGFRVSKINK
                     LGVEGAKNIADIQLAEITIKNSDLNTVSPQDLYDGYRLTIRGNTIANSVGKSISDISS
                     KDSETGKYKFTVKYTDTSGKAIELTVESTNDKELKDVKDALNGNTKVNLIAGEDRYAT
                     AVAIAKETEYTDNIVIVNSNKLVDGLAATPLAQSKKAPILLASDNEIPKVTLDYIKEI
                     IKKSPSAKIYIVGGESAVSNTARKQLESVTKNVERLAGDDRHTTSVAVAKAMGSFKEA
                     FVVGAKGEADAMSIAAKAAELKAPIIVNGWNDLTADAIKLMDGKEIGIVGGSNNVPSQ
                     IENQLADIDKDRKVQRVEGETRHDTNAKVIETYYGKLDKLYIAKDGYGNNGMLVDALA
                     AGPLAAGKGPILLAKNDITNSQKNTLDKKLNLGAEVTQIGNGVELTVVQKIGKILGW"
     gene            10053..10760
                     /locus_tag="OE968_002818"
     CDS             10053..10760
                     /locus_tag="OE968_002818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HCP7220086.1"
                     /translation="MIEATLFFSPHQDDETLSMGSAIIEHVERSDTHVILCTDGSKSI
                     IRKVLDDGGSCSYHIKDVHKYSLSESDFSKNRDEEFKNSCKAMGVKENNIHIENNRAH
                     DGELSKEKARDIMLKYLEKYPDAKVKTVTPYKALGIHEDHRALGEAALELYREGKIKD
                     LRFYVEPYDYNDFKKVNPNVRVWKVLSSQEEKLLNAMDAYKKWNPENGNYAIGYHSVK
                     SHFDELKSNKIQYVHAP"
     gene            10793..12925
                     /locus_tag="OE968_002819"
     CDS             10793..12925
                     /locus_tag="OE968_002819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HCP7220087.1"
                     /translation="MKISKRIMSLLTATFFIFALSINIADASSKESLVGSGRWETAIK
                     ISQNGWKDATNAILVNDNSIADALSATPFAKLKDAPILLTQSDKLDSRTKAELKRLGV
                     KNVYLIGGMNTLSTNIEKQLKSENMTFERISGNSRYETSLKLAERLDKEKSISDIVVV
                     NGEKGLADAVSVGSAAAQENMPIILSDPNNGIKVANSFISSKNIKKSYIIGGTYSVSS
                     SIEQSLPNVKRLSGNNRNETNAKVLEEFYKNTDLKNAYITKDGMKKQGDLIDSLAVGV
                     LAAKNSSPVVLVGNSLDSSQYDVLNTKSFDNIVQVGGNGNEDAVKDILDLQEETIYRV
                     KTADELDVALRKADANDIITFKPDDNKKITSSFSIETKKAITVELEGLYTQTITVNMP
                     NGELTNKGTLDGTVKIMDIKNGTFINEGDINDIDIYDPNGCKIENKSGGDIWVLTISS
                     SAKDVNIENKGDISKVTNNSTSVIIRNSGNIDTLSGINAPAISGNKPRVDDTDKDEKR
                     ASGIYPTSEPLSPARAGYISVKIFTKPEDTNYKIYYRVVSSRPSALYIGDRIDTSDWT
                     AVPSSVLPFTIKAENGYYIEAVEINSDTKKVSRWGKSDYIDDGFYLKSETAKGLSADI
                     DFDGDYVKLTATGADSGCTVYYRIVSKKPVSMNVGDKVTISDWDEITTNRVRIEANDV
                     KDKYIELVELDDSTNKVTRWGASDKVVE"
     gene            complement(12978..13373)
                     /locus_tag="OE968_002820"
     CDS             complement(12978..13373)
                     /locus_tag="OE968_002820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HCP7220088.1"
                     /translation="MILKKHRETILYLFFGAFTTLVNIVSYLFFTRVILFNFMVANAL
                     AWILAVLFAYVTNKFFVFESKRIELIFLFKEFLFFVSFRLLSGIIEMIIMYIMIDLFF
                     VNDITVKVFTNIIVIVLNYLFSKMIIFRK"
     gene            13600..16011
                     /locus_tag="OE968_002821"
     CDS             13600..16011
                     /locus_tag="OE968_002821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding cysteine protease Cwp84"
                     /protein_id="HCP7220089.1"
                     /translation="MRKYKSKNLSKLLALLTVCFLIVSTIPVSAENHKTLDGVETAEY
                     SESYLQYLEDVKNGDTAKYNGVIPFPHEMEGTTLRNKGRSSLPSAYKSSVAYNPMNLG
                     LTTPAKNQGSLNTCWSFSGMSTLEAYLKLKGYGTYDLSEEHLRWWATGGKYGWNLDDM
                     SGSSNVTAIGYLTAWAGPKLEKDIPYNLKSEAQGATKPSNMDTAPTQFNVTDVVRLNK
                     DKETVKNAIMQYGSVTSGYAHYSTYFNKDETAYNCTNKRAPLNHAVAIVGWDDNYSKD
                     NFASDVKPESNGAWLVKSSWGEFNSMKGFFWISYEDKTLLTDTDNYAMKSVSKPDSDK
                     KMYQLEYAGLSKIMSNKVTAANVFDFSRDSEKLDSVMFETDSVGAKYEVYYAPVVNGV
                     PQNNSMTKLASGTVSYSGYINVPTNSYSLPKGKGAIVVVIDNTANPNREKSTLAYETN
                     IDAYYLYEAKANLGESYILQNNKFEDINTYSEFSPCNFVIKAITKTSSGQATSGESLT
                     GADRYETAVKVSQKGWTSSQNAVLVNGDAIVDALTATPFTAAIDSPILLTGKDNLDSK
                     TKAELQRLGTKKVYLIGGENSLSKNVQTQLSNMGISVERISGSDRYKTSISLAQKLNS
                     IKSVSQVAVANGVNGLADAISVGAAAADNNMPIILTNEKSELQGADEFLNSSKITKSY
                     IIGGTATLSSNLESKLSNPTRLAGSNRNETNAKIIDKFYPSSDLKYAFVVKDGSKSQG
                     DLIDGLAVGALGAKTDSPVVLVGNKLDESQKNVLKSKKIETPIRVGGNGNENAFNELN
                     TLLGK"
     gene            16308..>16580
                     /locus_tag="OE968_002822"
     CDS             16308..>16580
                     /locus_tag="OE968_002822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HCP7220090.1"
                     /translation="MKAPKTILTILTIALTLSSISIIPSYALTEEKLIGNGRYETAVK
                     ISQKAYSSSPNVVLVNDNSLADALSATPFAKAKGAPILLTESDKLDD"
BASE COUNT         6693 a         1878 c         3124 g         4885 t
ORIGIN      
        1 agctaagaat ataacctctg taggtgaaat aaatgagaag gtaatacaac agtgtataaa
       61 tgcttcaaat tcaaatgggc aacccccaac aattacagtt ggaagtacag aggtatataa
      121 gggtgaaaag tttgacactg gcaagttaaa tatagtagct aaagataaca cagggaaggt
      181 attaccaata gaagttgatg ggtttataga tacaaataga gtaggtacat acatattgac
      241 attaaaagct acagacgaat ggggaaaaag cacaggaaaa agagtagaaa taaaagtgtt
      301 ggatgacaaa tctcatgatt acaacagccc agaatttaaa aaaatggtat ctactgaaat
      361 gtataactta atcaattcct atagaaaaga aaaaggcaaa gagcctttgc tagtgtctag
      421 taggctagaa ggtatggcaa atgcatggtc taagtatatg atggataaaa aagtatttgc
      481 acattatata gatggaaaaa atgctccaca agtattttct gaatttggaa tgagaagtga
      541 ggaaaatata gcatatattt atatagattc taagaacgtt caaacgacac aagatgcaaa
      601 agacttggca aaggctatat ttgaggtgtg gaagaagtct ccagagtaca atgcaaacat
      661 gcttagtaat gagttttata gtactggatt tgggctttat atattatctg atggtcaagt
      721 gcatgctact caggagtttt taaatggaaa tgaaggtagc ttgtaaaaaa ttccataaat
      781 cttgtttttt tgttaattta ctgatattat aaaatgaaaa tcacatctaa agtacttttt
      841 gtaatctgtt ttgttattgc tttacaggct atggtatttt aggtgttttt tgttttagta
      901 gtttatagat tttgagggaa tcactactga ggatgtaatt tatgattagc tgaattatat
      961 aaaaaaatta gtaggaggag tttgatgaag gtaaataaga gagtattatc aataggattg
     1021 acaatatcat taataatggc aggagcacca aatatcaatg cactttcgag catagaaaag
     1081 atacagggga aagatagata tgagacttct gcattgatag cagataaaca aatatatgat
     1141 acaatcatat tagtaaatac tgataattct atagtagatg gattaagtgc aagtggatta
     1201 tctggagttg caaaagctcc tataatgttg gtgcaaagag ataagatacc aacagatgtt
     1261 gaaaaaagac taaaggatgt taagaatgct tatgttatag gtacagagga tacaataggt
     1321 aaatctgtag aaaatcaact taagaataaa gggattgaag ttaaaagaat tggtggggaa
     1381 gatagaataa agactagcta tcttatagct aaggagattt cagctattaa accagtaaat
     1441 gatggtgata aggtttttct tgtaaatgga tacacaggtg aggctgatgc aatgagtgta
     1501 tcttctgtag ctgctagaga tggagttcct gtgatactta ctgatggaaa gagtatacca
     1561 tttaaagttg atggcgttca gtgctattct cttgggtcag aggagataat gagtaatgaa
     1621 cttgtgagta agactaattc agttaggatt gctggtaagg ataggtttga aactaataag
     1681 aaggttatac aacgctttta taaaggaaca aagaagtttt atgtttctca agggtataag
     1741 ttagttgatg ctgtggctgg ttctccgttg gctaaggaca aacctatagt acttgttaat
     1801 gatggaagtg ataagagtgt gcttagaggt gctgatgaag ttacttcttt aggtggaatg
     1861 gataagaagg ttgttgacca atgtattagt tctgcatctg ataaaaatac aatgcctaca
     1921 attactgcta atgatgtaga gatttctgta ggggataagt ttgataatag tatgttgaat
     1981 atagttgcta ctgattatta tggaaatgat ttaaaggcaa atattaaagg aaatgttgat
     2041 attaacaagg ctggaacata tgttttaaat ataagtgtag tggataattt aggtcagaag
     2101 agtgagatta gtgtaaatgt taaggtagtt gtaaatgcga gtacaaaaga ctctaatagt
     2161 tatgagttta aggctatggt atctaatgag atgtatgatt tagttaattc atatagaaaa
     2221 gaaaaaggca agaagagttt aagagagtta gactctttag ctggaatggc aaatgcatgg
     2281 tctaaatata tggaagataa gaaggtattt gcccatgaga ttgatggtaa aaatgcagct
     2341 gaagtatttt ttggctttgg agcaagaagt ggtgaaaata ttgcatatct accaatgaat
     2401 gttaaatctg tttatacttc taaagatgca aaagaaatgg ctgagtctat ttttgattta
     2461 tggaagaagt cttctaagta taatgaaaat atgttaaaag aagaatttta tagctttgga
     2521 tttggtatgc atgtttctag taaaggagaa gtgaatgcga caatggaatt tttaaatagt
     2581 tagattttat attaatttac attggaaaag atatagtaaa tttgtaaaaa taaatatata
     2641 aaattaaaat aacttataaa attataaaaa ataatttaaa aataataaaa atgatgaaaa
     2701 aacaattaat ttgttggaaa aaacttcaat taattttgca taaattattg aatttatatt
     2761 ttatatagtc tatcataaga gtgtgagaaa tatttggatt atatgaacat ggaaatttaa
     2821 tgtacataat taaagagatg taattaatat aatgttggga ggaatttaag aaatgaataa
     2881 gaaaaattta gcaatggcaa tggcagctgt tactgttgta ggttctgctg ctccgatatt
     2941 tgctgatact actgttaaag aagaaggata tacggtagta caagacaaat atgaaaaatt
     3001 acttaaagaa ttaaaggcaa agataaaaga tggaactatt acatcagttg gtgttgaatt
     3061 tgatggaaaa ccaattacta cattagcacc aaaggcagat ggtagtgata aagatgcaat
     3121 agcagaacag ttagaaactc ttactaaaaa ccaacttaaa ggtttaggtg atggaaaata
     3181 tgtagatttt aaaattactt atggtgctaa agcagaagtt ccagctgctt cattaagtgc
     3241 agatgatata caaaaatatg cagatcaaat aaatgcttct gagaaaatat tagttgaagt
     3301 agcagcagga tctgaagcag gtatagcaaa atttgattct gttaacaata aagttatagc
     3361 aggagatgct cctcttaaag ttaaagatgc agtgaaagcg actgttacta ctaatggtag
     3421 taataaaaaa gttcttacaa tatcagctgc agctggatta tcaggatttt catatggaac
     3481 acttaaagac acaggtgcaa gttcatctga tgttgatgca ataactcttg acactacaaa
     3541 tgcaacaata acagaaggtg atactaaagt attagatttt gataattcat ttaagtttaa
     3601 cgaaagtact aaaaaagttg gtagtttagt tacaccaaat acaacaaaca ctccagcaga
     3661 tcctggtact aaaactactg ttagagtgat aaaagctgtt gaaaaaacaa tagatgtaag
     3721 ttcaaattca actacaaaag ctaaagattt agctaaacaa tatgtattca cagatgttag
     3781 tgatactgat ccagaaagtt taagttatat gcttaaaaac ataaatgatg gaaaagttgc
     3841 tgttaaaaat tctgatggag attatgaagt aactatattc ccagaaggaa aaagattaaa
     3901 tactttatct gcttcttcag ctaaaactat tttaggagat aaagatactc cagcaaaaat
     3961 agttttaaag gcttcaacaa caaagaaatt agcagactat atagatgatt taataactta
     4021 taacaatagt tattcaaatg tacaaactgt agcaggtagt gatagaatag agactgctat
     4081 agagctaagc cgtaagtact ataactctac tgacaaaaat gctttatatg gagatcctgt
     4141 aaataacgtt gtattagtag gttctcaagc tatagttgat ggattagtag catctccttt
     4201 agcagcagaa aaagatgctc ctttattgtt aagttctaaa gataaattag attcatcaac
     4261 aagagctgag ataaaaagag ttatggactt aaattcttca acaggaataa aaaataataa
     4321 agaagttttc atagcaggtg gagtaaattc tatatctaaa gacgttgaaa atgaactaaa
     4381 agatatggga cttaaagtaa ctagattatc aggtgatgat agatatgaaa cttcattagc
     4441 gatagctgat gaaatagata taaatgataa agcttatgtg gtaggtggaa caggattagc
     4501 agatgctatg agtattgctc cagttgcatc tcaaataaaa gatggtgaag ctactccaat
     4561 agtagttgta gatggaaaat ctgacaagtt atctaaagaa gctgaagatt tcttagatga
     4621 tgcacaagta gatataatcg gtggagaaaa tagtgtttct gctaaaatgg aagattatat
     4681 agatgatgct actggaaaat ctccagaaag aattagtggt gctgatagac aagcaactaa
     4741 tgctgaagtt ataaaagaat actttgataa agatggagtt tcaaattact tcttagcaaa
     4801 agatggttca actaaagagg atcagttagt tgatgcatta gcagcagcag cagtagctgg
     4861 aaactacggt tctaagcata atgaagatgg agatataact acagatgctt ctcctgctcc
     4921 aattatttta gcaactgata atttatcagc tgaacaacat gtagctgtaa gtaaaactgc
     4981 tactactaat ggtgctaaga acttagtaca agtaggtcaa ggaatagctg attcagttgt
     5041 tagcaaatta aaagatttat tagatatgta atataaattt tatatattga ataaaaaagg
     5101 tttctctttt gagaaacctt ttttatttta aacataaatt tttataaata aaaagaggct
     5161 aattagcctc tttttaatgt gagaaacact taaaaaataa gatgtaatta tttatttaag
     5221 tatcattatt atactatacc ttaaaataaa tgtctactat tctataattt taaggtataa
     5281 tagtaagtgg aaaataaata aggaggtaaa ttaaatatgt cagttttaga tgtaatatta
     5341 gacaaaacag atgaattaga aattaaaaaa ttaaataata tagtagataa aatagatgct
     5401 ttagaagata aaatacaaat actagatgat gaagcattaa aaaatatgac gaatgtattt
     5461 aaggataagt taagtaaagg agaaacctta gatgacatat tgccagaagc atttgctgtt
     5521 gtaagagaag tatcaaaaag aatattaggt atgcgtcaat atagagttca attaattggt
     5581 gggattgtat tacatcaagg gaaaatagca gagatgagaa ctggagaagg aaagactcta
     5641 gtaggagtag ctccagttta cttgaatgca ttgactggta agggggtaca tgtcatcacg
     5701 gttaatgatt acttggctca acgtgataaa gaacttatgc aaccagtata tgaattttta
     5761 ggtttaacag taggagtaat tattaatggg caacagccag tagaacgaaa attacaatat
     5821 caatgtgata ttacttatgg tacaaacaat gagtatggat tcgattattt aagagataat
     5881 atggtaacgc aaaaatcaga gaaagttcaa agagaactaa actttgctat agttgatgag
     5941 gttgattcaa tacttataga tgaagctaga acaccactta taattgctgg tggaggagat
     6001 gaaggtacta agctgtatga acttgcaaat gcttttataa agaatataag agatgaagat
     6061 tttgaaatgg atagaaaaga taaaaccata gcacttactg caagtggtct tagtaaagct
     6121 gagaaatttt ttggaataga aaatataact catatagata atatagaaat ttttcaccat
     6181 gtaaatcaat ctctaagagc acataaatta atgaacatag atgttgaata tgttgttaga
     6241 gataatgaga tactaattgt agatgaattt acaggaagaa taatggatgg aagaaggttt
     6301 actgatgggc ttcatcaagc aattgaagct aaagagggag taaaaataaa tgatgaatca
     6361 aagaccatgg caacagtaac atttcaaaat ttctttagat tatactctaa attatcagga
     6421 atgacaggta cagcaaagac agaggaaagt gagtttgaag ctacatataa gattaatgtt
     6481 gttcagatac caactaataa accagttata agagctgatt tacatgataa agtattcaaa
     6541 acagaacgtg caaagtacaa tgctgttgta gaagaaataa taaggataaa taaaactaag
     6601 caaccagtgc ttgtaggaac tgtttcaatt gaaaaatctg agaaattatc taagctactt
     6661 aaaaagaaag gtgtaaagca cgaggtctta aatgctaaac aacatgataa ggaagctgaa
     6721 ataatatcta aagctggtaa attaggttct gttacaattg ctactaatat ggcaggtaga
     6781 ggaactgata tatcacttgg agctggagat aaagaagaag aagaaaaggt gaaagagtta
     6841 ggtggcttgt atgttatagg tactgaaaga catgagacaa gaagaattga taatcagctt
     6901 agagggcgtt cgggaagaca aggtgaccct ggaacttcta gattctttgt aagtttagag
     6961 gatgaagtaa taaaattgta tggtggaaaa agtatagaaa aaatattaaa gagaatgaat
     7021 gctaatgaag atgacgcgtt agaaagtaag gctttgaata gagcaataga aagagcacag
     7081 aaaggcattg aaggtaaaaa ttttgaacaa agaaagaatg ttcttaagta cgatgatact
     7141 attaatgagc aaagaaaagt aatatatgat gaaagaaata aggtattgga tggttctgat
     7201 attgaagaag agatacaaaa aatggttatg gatattatta cggaggctgc tgaaaagtac
     7261 ttaaaaaaat ttagagacta tcatggatat tttaagtatt tatataatac ttttatgcca
     7321 gctgatactt tattaattcc agacttagat aaaaaaaatg ttgaagaaat agtaaatcaa
     7381 acatatcaga tttcaaagcg tgtttatgat cttaagaaga tgatgattgg aattgaagaa
     7441 ttggctcaat tagagaaacg agtattactt caagttgtgg atacttattg ggttgaccat
     7501 atagatgcaa tggatcaact aagacaatat ataggtctta aatcttatgc acaaaaagat
     7561 ccatttaaag agtatgctat agaaggttat gaaatgtttg aagctttaaa taggaatata
     7621 agaataacaa cagtgcaata tctatataaa tttaactaaa aaagtgaccc attgggtcac
     7681 tttttatata ttaagattaa agtgaaattt attttacagt acacactcat atagataaat
     7741 atttataata atgaaaaaga ggctgaacgt cagcctcttt tcctgtgtga gaaatacgga
     7801 aaaaagagat gcttgaaatt tctttcttcc atttaatatt atactataaa gagaataaaa
     7861 agtccatgag ttatctttat gattaaaaaa aaaaattaca attttgttac tttttagtat
     7921 acaataataa atttaaattg actttgttaa tttttattaa taaaatatcc aaatattaca
     7981 atatctacag tttattgaaa taatgtgtaa attatattat aattggtaaa taaggaaaaa
     8041 tggtgaaaac caaattttgt agggggaaat atatgaatag aaaaaatctt tatgtaatta
     8101 tggcagctgc aatggtaagt acatcagtag ctccaagttt tgctgcagaa gctacacaag
     8161 taaagaaaca aacaataact aaaaaggaag caacagaatt agtttctaaa gttagagaac
     8221 taatggctca gagatataca ggaggttctc aagttggaca accaatatat gaaataaaag
     8281 ttggtgaaac ttcatcacaa ttaaaaataa taactaatat agacgaatta gagaaattag
     8341 taaatgcttt aggagaaaat aaagagcttc ttgtgactat agcagataaa ggacatacaa
     8401 caaatagtgc aaatgaagtg gttgctgaag caattgaaaa atatgaaaat tcagcagacc
     8461 tttcagctga agctaattca ataacagaaa aagctaaaac tgaagctact gggatttatg
     8521 gagtggcaac tgtagaagct tcatatgaca gtacaaaaga taagttagta ataactttaa
     8581 aagataagac tgatgtagta acttctaaaa cgctacaaat aggtattggt gatgaaaagg
     8641 ttgatttaac agcaaatcca gttgatatag caggaaccaa tttagaccct tctgcagaag
     8701 gatttagagt aagtaaaata aataaattag gtgtagaagg agctaaaaat attgctgata
     8761 ttcaattagc tgaaataact ataaaaaata gtgatttaaa tacagtttca cctcaagatt
     8821 tatatgatgg atatagattg actattcgag gtaatacaat agcaaatagt gtaggaaaat
     8881 caattagtga tatttcatca aaagattcag agacaggaaa gtataaattt actgttaaat
     8941 atactgatac atctggaaaa gcgatagaac ttactgtaga aagtactaat gataaagagt
     9001 taaaagatgt taaagatgcc ttaaatggaa atacaaaagt caatttaata gctggggaag
     9061 acaggtatgc aactgctgta gctatagcaa aagaaacaga atatactgac aatatagtta
     9121 tagttaattc aaataaatta gttgatggat tagcagcaac accactagct caatctaaaa
     9181 aagctcctat attgttggcg tctgataatg aaataccaaa agtaacttta gattatataa
     9241 aggaaataat taaaaaaagt ccatcagcta aaatatatat agtaggtgga gaatcagcag
     9301 tatcaaatac agctagaaag caattagaat cagtaactaa gaatgttgaa agattggctg
     9361 gagatgatag acatacaact tcagtagcag tagcaaaagc tatgggttct tttaaagaag
     9421 catttgtagt aggtgcaaaa ggggaagctg atgctatgag tatagctgct aaagctgctg
     9481 aacttaaggc tcctataata gtaaatggtt ggaatgatct tacagcagat gctatcaagt
     9541 tgatggatgg aaaagagatt ggtatagttg gtggttctaa taatgtacct agccaaattg
     9601 aaaatcaact tgctgatatt gataaagata gaaaggttca aagagttgaa ggtgaaacaa
     9661 gacacgatac taatgctaaa gttatagaaa catattatgg caaattagat aaactatata
     9721 tagcaaaaga tggatatgga aataatggta tgttagtaga tgcattggca gcaggtcctc
     9781 tagcagcagg aaaaggacca attcttttag ctaaaaatga tataacaaac tcacaaaaga
     9841 atactttaga taaaaaacta aatcttggtg cagaagtaac tcaaataggt aatggggttg
     9901 aattgactgt agttcaaaaa ataggcaaaa tactaggatg gtaataatca ataatataga
     9961 aaaggattcc ttattattta taggaatctt tttctatcga cataatattc attaaagtat
    10021 aacatgctct tgacagatag gaggatatga tagtgataga agcaacattg tttttttccc
    10081 cacaccaaga tgatgaaaca ttaagtatgg gtagtgcaat aattgaacat gtagaaagaa
    10141 gcgatacaca tgttatatta tgtactgatg gcagtaaatc aataataaga aaagtattag
    10201 atgatggagg gtcatgttct tatcatatta aagatgtaca caagtactct ttatcagaaa
    10261 gtgatttttc aaaaaataga gatgaagaat ttaaaaatag ttgtaaagca atgggagtta
    10321 aagaaaataa tatacatata gaaaataata gagctcatga tggagaattg agtaaggaaa
    10381 aagcaagaga tataatgcta aaatatttag aaaaatatcc tgatgctaaa gtgaagaccg
    10441 ttacaccata taaagctctt ggaatacatg aagaccatag agcattaggt gaagctgcat
    10501 tagaattgta tagagaagga aaaataaaag atttaagatt ttatgtagag ccatacgatt
    10561 ataatgattt taaaaaagtt aatccaaatg ttagagtatg gaaggttttg agtagtcaag
    10621 aagagaaatt attaaatgct atggatgcat acaagaaatg gaatcctgaa aatggtaact
    10681 acgcaattgg atatcattct gtaaaatctc actttgatga attaaaatcc aataaaatcc
    10741 aatatgtaca tgctccataa acattaatat aaaaactagg aggatatagt taatgaaaat
    10801 atctaagaga ataatgtcgt tgttgacagc aacttttttt atctttgcat tatctatcaa
    10861 tatagctgat gcttcatcaa aagagagtct agtgggctct ggtagatggg aaactgcaat
    10921 aaaaattagt cagaatggat ggaaagatgc tactaatgct atactagtaa atgataattc
    10981 tatagctgat gcattatctg caactccatt tgctaagtta aaagatgcac ctattttatt
    11041 aactcaaagt gataaattgg atagtagaac taaagcagaa ttaaaaagac taggtgtaaa
    11101 aaatgtatat ttaattggag gtatgaatac tctaagcacc aatattgaaa aacaattaaa
    11161 atcagaaaat atgacttttg agaggatttc aggtaatagt agatatgaaa catctttaaa
    11221 attagctgaa agattagata aagagaagag tatttctgat atagttgtag ttaatggaga
    11281 gaaagggcta gcagatgcag taagtgtggg ttctgctgca gcacaagaaa atatgccaat
    11341 tatactttca gatcctaaca atggaataaa agttgcaaat agctttatta gtagtaaaaa
    11401 tataaagaaa tcttatataa ttggtggtac atattctgta tctagttcta ttgaacagag
    11461 tttacctaat gtaaaaagat tatctggaaa caatagaaat gaaactaatg caaaggttct
    11521 agaagaattt tataaaaata cagacttaaa aaatgcttat ataactaaag atggtatgaa
    11581 aaaacagggg gatttgatag attctctagc tgtaggtgta ttggcagcta aaaatagctc
    11641 tccagttgta ttagtaggaa attcacttga ctctagccaa tatgatgtgt taaatactaa
    11701 aagttttgat aatattgtgc aagttggtgg aaatggaaat gaagatgctg taaaggatat
    11761 tcttgattta caagaagaaa ctatatatag agttaagaca gcagacgaat tggatgttgc
    11821 tctaagaaaa gcagatgcta atgatattat aacatttaaa cctgatgata ataaaaaaat
    11881 tactagttca tttagtatag aaacaaagaa agctataact gtagagcttg aaggattgta
    11941 tacacaaaca ataactgtaa atatgccaaa tggagaatta actaataagg gtacattaga
    12001 tggaactgtg aaaataatgg atataaaaaa tggcacattt atcaatgaag gtgatataaa
    12061 tgatattgac atttatgatc caaatggatg taaaatagag aataaaagtg gtggagatat
    12121 atgggtttta actatatcta gtagtgctaa agatgtaaat atagaaaata aaggtgatat
    12181 aagtaaggtt acaaataatt ctactagcgt tataataaga aattcaggaa atattgatac
    12241 tttaagtgga attaatgcac cagcaataag tggaaataaa cctagagttg atgataccga
    12301 taaggatgaa aaaagagcaa gtggaatata tcctacttca gaacctttat cacctgcaag
    12361 agctggttat ataagtgtaa aaatattcac taagcctgaa gatacaaatt ataaaattta
    12421 ttatagagta gtaagcagta gaccatctgc attatatatc ggagatagaa tagatacaag
    12481 tgactggact gctgtaccat cttctgtttt accatttact attaaagcag aaaatggata
    12541 ttatatagaa gctgttgaaa taaattctga tactaagaaa gtatctagat gggggaaatc
    12601 tgactatata gatgatggat tttatttaaa atcagaaact gcaaaaggat taagtgcaga
    12661 tatagatttt gatggagatt atgttaaatt aacagcaaca ggtgctgatt ctggatgtac
    12721 agtttattat agaatagtat caaaaaagcc agtatcaatg aatgttggag ataaagtaac
    12781 tatatctgat tgggatgaaa ttactactaa tagagtgagg atagaagcaa acgatgtaaa
    12841 ggataaatat atagaactag ttgaattgga tgattcaact aataaagtaa ctagatgggg
    12901 agcaagtgat aaggtagtag aataggtatc taatgtgaaa cataaaaaca gactgattaa
    12961 taatgggcag tctgttttta tttcctaaaa attatcattt tactaaataa ataatttaaa
    13021 actataacaa ttatattagt aaatactttt acagtaatat catttacaaa aaataaatca
    13081 atcattatat acataataat catttctata ataccagaaa gtagcctaaa actgacaaaa
    13141 aacaaaaact ccttaaacaa aaatattagt tcaattcttt tactctcaaa cacaaaaaac
    13201 ttattagtaa cataagcaaa taaaacagca agtatccatg ccaaagcatt tgcaaccata
    13261 aaattaaata aaataactct agtaaaaaat aaatacgaaa ctatatttac aagagtagta
    13321 aatgctccaa aaaataaata taatatcgtc tctctatgct tttttaaaat caaatataat
    13381 cctcctaagc taatttaata taaatatact taaagatact aacaaacatt agtataacac
    13441 atctattaat aaatcaatat atcttaaaat attataaaaa taaaactata atattctata
    13501 attaatatgt actcataatc catattttat caaaataaaa tatgacctta atttagaaat
    13561 ctgatataat aaaaattaaa tacatataag ggggtaaaca tgagaaagta caaatcaaaa
    13621 aacttgtcaa agctactagc attgttgaca gtttgctttt taatagtgtc aacaatacct
    13681 gtctcagcag aaaaccataa aactctagat ggagtagaaa ctgcagagta ttctgaaagc
    13741 tatcttcaat acctagaaga tgtcaaaaat ggagacacag caaaatataa tggagtaata
    13801 ccttttccac atgaaatgga aggtacaaca cttcgaaata agggtagaag tagtcttcca
    13861 tcagcatata aatcaagtgt agcatacaac ccaatgaatc ttggtcttac tacaccagca
    13921 aaaaatcaag gaagtcttaa tacatgctgg tctttttcag gtatgtcaac gttagaagca
    13981 tatcttaaat taaaaggata tggaacgtat gacttatcag aagaacattt aagatggtgg
    14041 gcaactggtg gaaaatatgg atggaactta gatgatatgt cagggagttc aaatgtaaca
    14101 gctataggat atctgacagc atgggcaggt cctaagttag aaaaggacat accatataat
    14161 cttaaatctg aggcacaagg tgcaactaaa ccttcaaata tggatactgc acctactcaa
    14221 tttaatgtaa cagatgttgt tcgtcttaat aaagataagg aaactgtaaa gaatgctata
    14281 atgcaatatg gttcagtgac atcaggttat gcacattatt caacatattt taataaagat
    14341 gaaacagcat ataactgtac aaataagaga gctccattaa atcacgctgt agcgatagta
    14401 ggatgggatg ataattattc aaaagataat tttgcatctg atgtaaaacc agaatcaaat
    14461 ggagcatggt tagtaaaaag tagttgggga gagtttaatt ctatgaaagg attcttctgg
    14521 atttcttatg aagataaaac tctactaaca gatacagata actatgcaat gaaatcagta
    14581 tcaaaaccag atagtgataa aaaaatgtac caacttgaat atgctggtct tagcaagata
    14641 atgtcaaata aagtaacagc agcaaatgta tttgatttta gcagagactc tgaaaaactt
    14701 gattctgtta tgtttgaaac agactctgta ggagcaaaat atgaagtata ttatgcacca
    14761 gtggtaaatg gagttcctca aaacaattca atgacaaaac ttgcaagtgg aacagtatca
    14821 tattctggat acataaatgt acctactaat tcttacagct taccaaaagg taaaggagca
    14881 atagtagtag ttatagacaa cacagcaaat cctaatagag aaaaatcaac tttagcatat
    14941 gaaactaata tagatgcata ttatttatat gaggctaaag caaacttagg tgaaagctac
    15001 atacttcaaa acaataagtt tgaggatata aatacatata gtgaattttc tccttgtaac
    15061 tttgttataa aagctataac aaaaacatct tctggacaag ctacttcagg agaatcttta
    15121 actggagcag atagatatga aacagcagtt aaagttagtc aaaaaggatg gacttcttca
    15181 caaaatgcag tattagtaaa tggagatgca atagtggatg ctttaacagc tacaccattt
    15241 acagcagcaa ttgactctcc aattcttttg acaggaaaag ataacttaga ttcaaaaact
    15301 aaggcagagt tacaaagatt aggaactaaa aaagtttatc taataggtgg agaaaattct
    15361 ttaagcaaga atgtacaaac tcaacttagt aatatgggta tatcagtaga aagaatttca
    15421 ggtagtgata gatacaagac cagtatatct ctagctcaaa agttaaatag tataaaatct
    15481 gtttcacaag ttgcagtggc aaatggtgta aatggacttg cagatgcaat aagtgttggt
    15541 gcagcagctg ctgataacaa tatgccaata atacttacta atgaaaaaag tgagttgcaa
    15601 ggtgctgatg agtttttaaa ttcatctaaa ataactaagt cttatataat tggtggaaca
    15661 gctactttat catcaaattt agaaagtaag ctttcaaatc caacaagact tgcaggcagt
    15721 aatagaaatg aaactaatgc taagataata gataaattct accctagctc agatttgaaa
    15781 tatgcttttg ttgttaaaga tggttcaaag agtcaaggag acttgataga tggactagca
    15841 gtaggagcat tgggtgctaa aactgattca ccagtagttc tagttggaaa taagttagat
    15901 gaaagtcaaa aaaatgtact taagtctaag aaaatagaaa ctcctattag agttggtgga
    15961 aatggaaatg aaaatgcttt taatgaacta aatactcttt taggaaaata gtgaatggaa
    16021 agatagtaag gatatacatt ttattattaa aaaatgttca atagaagttt ataaatataa
    16081 aataacaaaa aggggtgtct caaaatgaac tttttagttc atgaggcact cttttttgtt
    16141 gttttatatt tttatcattt aaataatgaa aaataggatt gtctatattt ttagatagtt
    16201 ttcttattat tgatgaaaaa tgtaataatt ttaaactgta aaatagtgta aagttatttt
    16261 ataatataaa tatagtaaga ttttaaacaa aataaggggg aataataatg aaagcaccaa
    16321 aaactatttt aacaatactg acaatagcgc ttactttaag tagcatttct ataataccat
    16381 catatgcact tacagaggaa aaattaatag gtaatggtag atatgaaact gctgtaaaga
    16441 taagtcaaaa ggcatacagt tctagtccta atgtagtgct agttaatgac aattcattag
    16501 ctgatgcact ttcagctaca ccatttgcaa aggctaaagg agcaccaata cttttgacag
    16561 aaagtgataa gctagatgat
//
LOCUS       DAJMZY010000090        16533 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.090, whole genome shotgun sequence.
ACCESSION   DAJMZY010000090 DAJMZY010000000
VERSION     DAJMZY010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16533)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16533)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16533
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.090"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            157..504
                     /locus_tag="OE968_002823"
     CDS             157..504
                     /locus_tag="OE968_002823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HCP7220091.1"
                     /translation="MHENKKNLLDGSLAQYNDTAVPKIPVFAGNDITSEVYYFKPNQV
                     LNAHRHPNGEQIFVFLKGEGKMKLGEHECDVKNGDTVFVPTGEWHEITNGSNEEMVAV
                     QITKINAGAEYRG"
     gene            complement(654..1703)
                     /locus_tag="OE968_002824"
     CDS             complement(654..1703)
                     /locus_tag="OE968_002824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HCP7220092.1"
                     /translation="MFKKIVAIASSIIVSTICLTGCDFNSNDKKDESSSSKNLDKVTI
                     AEVTHSVFYAPQYAAITKGFFEDEGIKIDLINTQGADKTMAALISGEANVGLMGPEAS
                     IYVYNQNKNDYAVNFAQLTKRDGSFLVARKKMPNFSYNDLKGTEILGGRKGGVPLMTF
                     EYVLKEKGLTIGENLKAGNVNVRTDVQFGVMAGAFAGGEGDFTTAFEPTATAMEKEGS
                     GYIVTSIGKDSGEIPFTAYSTTRSYMKNNKDLIQRFTNAVYKGQLWIQQASSKEVAKA
                     MQPFFEDISLEDLTTVVDRYKSIDAWSQNPVLKEEGLKKLMTVMKEAKELDKEAPYKD
                     IVNTEFANNAIKNIK"
     gene            2089..2823
                     /locus_tag="OE968_002825"
     CDS             2089..2823
                     /locus_tag="OE968_002825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HCP7220093.1"
                     /translation="MKQNKYDDDRFFNKYSKMERSTNGLAGAGEWHVLKKMLPDFKGK
                     RVLDLGCGFGWHCQYAVENGAISAVGVDISEKMLKEARNKTQLDNINYICMPIEDINF
                     PKDSFDVVISSLAFHYIQSFEDICKNISNCLSNKGNFVFSVEHPIFTAYGSQEWYCDK
                     DGNNLHWPVDRYFEEGVRRSNFLGEEVIKYHKTLTTYLNALMKTGFEILEIIEPQPEE
                     KLLDTIPDMKDELRRPMMLLVSAKKR"
     gene            complement(2966..3457)
                     /locus_tag="OE968_002826"
     CDS             complement(2966..3457)
                     /locus_tag="OE968_002826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HCP7220094.1"
                     /translation="MNNQQQEVYKKLDELSIPYEAVNHPPVYTIEEMEELKTLHMEFV
                     VKNLFLRDAKGKEHFLVVLGKDKKADLKDIRQQIDSKPLSFASEERLQKYLKLTKGAV
                     TPFGILNDKEAVVKVVFDKDLLKMDKIGIHPNDNTATVFLKFEDMKKLIEENGNEIYY
                     VEV"
     gene            3806..4189
                     /locus_tag="OE968_002827"
     CDS             3806..4189
                     /locus_tag="OE968_002827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220095.1"
                     /translation="MSTDKVVGIIDEETAELAGIEYTGKIYASSGVIKHIKKKHRCQL
                     SKDIFNDIIDTIKMVLKSPEYIGSHPKKPGKSVEFIKKIDDYILVATELDTKKGYLYV
                     SSMYAIKEAKLESRVNSGRVKQYDG"
     gene            4697..5080
                     /locus_tag="OE968_002828"
     CDS             4697..5080
                     /locus_tag="OE968_002828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HCP7220096.1"
                     /translation="MNLSKKIEDKRKAKQRAEKVKKAKIATAGVVLGAVTGAVSGVLL
                     APKSGKETREDIKDASQQIAEKINMKTVDVKGKVSEKLEDKKGNFIESKKKIKKYIDN
                     KKSVENSSEEDKIIDIVEPVSVTEE"
     gene            5082..5432
                     /locus_tag="OE968_002829"
     CDS             5082..5432
                     /locus_tag="OE968_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220097.1"
                     /translation="MDNTITINISIIYVLLAILACIALVYLIIVLVKLHKILNNVGTM
                     LNENTQNINTTLNNLPNVVETFGEVGENMKDVTEVVTEVTADFLVTKDSVKSNMDVIV
                     DILTIIKNIFVDKK"
     gene            complement(5533..5991)
                     /locus_tag="OE968_002830"
     CDS             complement(5533..5991)
                     /locus_tag="OE968_002830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220098.1"
                     /translation="MIRTKVVELIATVCRENKPHKWVDENYTPYDKSGKVELMSIEDL
                     NELISSSGRADFLYSSRLQKLLNEVYINQSRASYISGCGLFWSSYWDILEEKFEEWLY
                     NSYIFFDEDDEYLEGMEDFELECKDVLMDVIETTSIDIYVQMIKRNITNY"
     gene            complement(6036..6824)
                     /locus_tag="OE968_002831"
     CDS             complement(6036..6824)
                     /locus_tag="OE968_002831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HCP7220099.1"
                     /translation="MKVVIIPGHTLIGKGTGAVGYINESKETRILNDLIVKWLKIGGA
                     TVYTGRVDESSNHLADQCAIANKQETDLAVQIHFNSNATTSTPVGTETIYKTNNGKTY
                     AERVNTRLATVFKDRGAKSDVRGLYWLNHTIAPAILIEVCFVDSKADTDYYVNNKDKV
                     AKLIAEGILNKSISNSQGGGENKVYENVIVYTGDADKVAAQILHWQLKDSLIIEASSY
                     KQGLGKKVYVVGGEANKLVKGDVVINGADRYETVKLALQEIDKL"
     gene            complement(6963..7400)
                     /locus_tag="OE968_002832"
     CDS             complement(6963..7400)
                     /locus_tag="OE968_002832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HCP7220100.1"
                     /translation="MNKKLENRCSWQEYFMRLCETVAERGTCDRAYVGAIIVNSENRI
                     VSTGYNGSISGDKHCSEVGHEMRDGHCIRTIHAEQNALYYCAKEGISVKNCSIYVTHF
                     PCLNCTKAIIQAGIKHIYYRTGYRIDEYAIKLLQSSNVLYTKL"
     gene            8222..8731
                     /locus_tag="OE968_002833"
     CDS             8222..8731
                     /locus_tag="OE968_002833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCP7220101.1"
                     /translation="MLSENIKTIRKSKGLSQQELAIKLNVVRQTISKWEQGLSVPDSD
                     MLISISEVLETPVSTLLGETIVESEVDNLKVISEKLEIINLQLAQRKNMRRKMFHWLF
                     ILLCAVILIVFVVLGRLNSPYLDWNYTDPETAVFGVAFHAFEWLFVRLVPIVLIGAII
                     GIFLTRKKI"
     gene            9145..9576
                     /locus_tag="OE968_002834"
                     /pseudo
     CDS             9145..9576
                     /locus_tag="OE968_002834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016295744.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
     gene            complement(9763..9956)
                     /locus_tag="OE968_002835"
                     /pseudo
     CDS             complement(9763..9956)
                     /locus_tag="OE968_002835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227347.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
     gene            10058..10564
                     /locus_tag="OE968_002836"
     CDS             10058..10564
                     /locus_tag="OE968_002836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HCP7220102.1"
                     /translation="MKNEKKITVALLIVYLLILSWIILFKLQFSFSALDHIRQINLIP
                     FGGSVIANGKIDFDEIINNAIVFIPVGAYFSLLFKNKSVLKAIGSVLGISFVYEIIQF
                     IFAIGASDITDLISNTLGGIIGIALVYVLSIVLKDKTHKILNRIAIVCTVLVVAFLFM
                     LLAVNNIF"
     gene            10569..10845
                     /locus_tag="OE968_002837"
                     /pseudo
     CDS             10569..10845
                     /locus_tag="OE968_002837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436830.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4865 family protein"
     gene            11114..11686
                     /locus_tag="OE968_002838"
                     /pseudo
     CDS             11114..11686
                     /locus_tag="OE968_002838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902350.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
     gene            11789..12604
                     /locus_tag="OE968_002839"
     CDS             11789..12604
                     /locus_tag="OE968_002839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HCP7220103.1"
                     /translation="MFKIGEFSKLTQVSTRMLRYYDETGLLKPAKIDSLTGYRMYSAE
                     QISTLNRIIYLRDSGFNVAEIALALNFSNNAIIEQLDRKSIEIMDNIQKEQEKLKKIE
                     IAKKEVLHGKSELYFNITIKEIPSYCVLSLRKEIPNYYYEGELWKELSAFAKENKINI
                     SDETFSIYHNEEYKEKDVDVELCAIVNKIGKATGDFKFRFTEPVSMMACTMVYGDFSN
                     ISYAYRSFAKWLQENSQYKMKGSSRQIVHRGPWNEKNPENYLTEIQIPLENLL"
     gene            12685..13161
                     /locus_tag="OE968_002840"
     CDS             12685..13161
                     /locus_tag="OE968_002840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002608187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase"
                     /protein_id="HCP7220104.1"
                     /translation="MTTYKVNSIGTICNNEKGAFIQLEAPYILALRALDGFSHINVLW
                     WFSDFDNTNFRSVLETEQPYKNAPEKMGIFATRSPVRPNPIALSAVEIIDIDYMSGLI
                     QIAYIDANDKTPILDIKPYTPSLDRVENPQVPDWCSHWPHSLEESASFAWESEFNF"
     gene            13175..13738
                     /locus_tag="OE968_002841"
     CDS             13175..13738
                     /locus_tag="OE968_002841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCP7220105.1"
                     /translation="MSLQDYIFEKPVIETEHLILRTMNKNDIDDLKEWISDISLYEYW
                     GKRPSKSEKNPELLFDKSKKSTKSFHWGIVHKQDSKVIGEIWIYLIENNRMAKVAFRL
                     SKHYQGNGLMSEVLKNVIEFCFSKTELQKIWTDVHILNHASYKTLEKVGFQREGHIRG
                     GKMVNTYCDYYLYGILKSDYITRWCYG"
     gene            13993..14904
                     /locus_tag="OE968_002842"
     CDS             13993..14904
                     /locus_tag="OE968_002842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HCP7220106.1"
                     /translation="MYAYENIEMSLNYIEQHLSEKIETEKLAEIACLSTFYYQRLFKR
                     LVKKSVQEYIKLRRLAMVIAELNNSEERILDIALKYGFSDHANFTRAFKEVYHITPDE
                     YRKNVPMLNTFDKPELSSRYIMIDENVPLIVGNIVLEIQRKTLRTKETYFGFEKTVNI
                     SEQIPAGESTGIDVPGQLWREFHAKKLQTENAIFNNDIELGVSHLASPDKGTFLYFAG
                     GMVSSTDVCPKNMVQHTLPAGEYIVCKIEAESFEELVTTALNQANKYLFETWLPNHNL
                     VTKPFMAEKYYKGNAEINYMEIWIIPV"
     gene            14982..15416
                     /locus_tag="OE968_002843"
     CDS             14982..15416
                     /locus_tag="OE968_002843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3788 domain-containing protein"
                     /protein_id="HCP7220107.1"
                     /translation="MINIKDINYVPNISEISVYIENSAFDELYQHMNNEYKAVCKIEY
                     SKDVWARGWNVKFKKSGKSLCVVYPKKNYFTVLVVVGNKEKEDVENLLPRLSEYVQEI
                     YRNTREGNGQRWLMIDLKSKNNVYQDVLRLIEIRYAIKCVKP"
     gene            15884..16533
                     /locus_tag="OE968_002844"
                     /pseudo
     CDS             15884..16533
                     /locus_tag="OE968_002844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009243519.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
BASE COUNT         5956 a         2312 c         2682 g         5583 t
ORIGIN      
        1 cttataagga ttgtattttt ctaactataa aaatagtatt atacttatat ttaaaaataa
       61 aagaatttta ttcctattgt gtaaagtgag aatactattt tcttatattg gtataataat
      121 agtaaatcta taatatagaa aagaggtatt tctagtatgc atgaaaataa aaaaaatcta
      181 ttagacggaa gcttagctca atataatgat acagcagttc caaaaatacc agtatttgct
      241 ggtaacgata taacttcaga agtttattat tttaaaccta atcaagttct taatgctcat
      301 agacacccta atggtgaaca aatatttgtg ttcctaaaag gagaaggtaa aatgaaactt
      361 ggtgagcatg aatgtgatgt aaaaaacgga gatactgtat ttgtaccaac aggagagtgg
      421 catgaaatta ctaatggaag caatgaagaa atggtagccg ttcaaattac aaaaattaat
      481 gctggagcag aatacagagg atagatatat aagtacagtt agtactttaa tatctatttt
      541 attatataaa ctttaatctc aaatataaaa agagtctttt aaaaggctct ttttatattt
      601 ttgttaattt tcattataaa aacaagaaaa tatctagcta aaactaatat attttattta
      661 atatttttta tagcattgtt tgcaaactca gtatttacga tatctttata aggtgcttcc
      721 ttatctagtt ctttagcttc tttcataaca gtcatcaatt tcttcaaacc ttcctctttt
      781 aatacaggat tttgagacca tgcatctatt gatttatatc tatctacaac tgttgttaaa
      841 tcttctaaag atatatcttc aaagaaaggt tgcatagcct tagctacttc tttgctagat
      901 gcttgttgaa tccataattg acctttataa acagcatttg taaatctttg aattaaatct
      961 ttattgtttt tcatgtatga tctcgtagta gagtatgctg taaaaggtat ttctccagaa
     1021 tcttttccta tagatgtaac tatatatcca ctaccttctt tttccattgc tgttgctgta
     1081 ggttcaaatg ctgttgtaaa gtcaccctct ccacctgcaa aagctccagc cattacacca
     1141 aattgtacat cagttcttac attaacattg cctgctttta gattttctcc aatagtaaga
     1201 cctttttctt ttagaacata ttcaaaagtc attagtggaa ctccaccttt tctaccacct
     1261 aatatttcgg ttccttttaa atcattgtaa gagaaattag gcattttttt cctagcaact
     1321 agaaaactac catctctttt tgtcaattga gcaaagttca ctgcataatc gtttttgttt
     1381 tgattatata catatataga tgcttcagga cccattaaac ctacgtttgc ttcacctgaa
     1441 atcaaagctg ccatagtttt atctgcacct tgggtattta taaggtcaat ctttatacct
     1501 tcatcttcaa agaatccttt cgtaatagca gcatactgtg gagcataaaa aacagagtga
     1561 gtaacttctg ctatagttac tttatccaga tttttagacg aagaagattc atcttttttg
     1621 tcattagagt taaaatcaca tccagttaga catattgtac ttacaatgat agagcttgct
     1681 attgcgacta tttttttaaa cataataaat acctcccata agacatacga atagtatata
     1741 gtattaaata tttattgtag ttgttacaaa aatgtatcta tacttataat atttctacaa
     1801 aaacttaata ataattttca gttttatgtt tagttttttc agtaatgtgt aatattggat
     1861 aaattatatt gattatttat aaactaagta ataaaattaa aataatatca cttttttgtc
     1921 tattatatat aaggaaaaat tttttaataa tataaatcat attcatttat attattaaaa
     1981 aatttgttta tagaaacttt tattatttta tataaaagtg ataaaaactt atattttgta
     2041 tttaatagag tgttgctaag tgaatatatt taaaatggag gaaactttat gaaacaaaat
     2101 aaatatgatg atgatagatt ttttaataaa tacagtaaaa tggaacgttc tacaaatgga
     2161 ttagcaggtg ctggagagtg gcatgtttta aaaaaaatgt tacctgattt caaaggaaaa
     2221 agagttttag atttaggatg tggatttgga tggcattgtc aatatgcagt tgagaatgga
     2281 gcaatttctg ctgttggagt tgatatttca gaaaaaatgt taaaagaagc tagaaacaaa
     2341 acgcaacttg ataatataaa ttacatatgt atgcctattg aagatattaa ttttccaaaa
     2401 gatagttttg atgtagttat tagttccttg gcatttcatt atattcaatc atttgaagat
     2461 atatgtaaga atataagtaa ttgtctttca aataaaggta attttgtatt ttctgttgaa
     2521 catcctatat ttactgcata tggaagtcaa gagtggtact gtgataaaga tggaaataat
     2581 ctacactggc cagtagatag atattttgaa gaaggagtac gtaggtcaaa ttttctagga
     2641 gaagaggtta taaaatatca taaaacatta acaacttatt taaatgcgtt aatgaaaaca
     2701 ggatttgaaa tattagaaat tattgaacct caaccagaag aaaaactgtt agatacaatt
     2761 cctgatatga aagatgagct acgtagacct atgatgttac ttgtatctgc aaaaaaaaga
     2821 taagtaaata taaataatca ttattgtaga aaaaaagttg tagaaaataa ttacactaat
     2881 ggagatgatt ataccagtgg tattaattac accagtagta aggaggcaaa agcattcgtt
     2941 gcttttgcca ttttttaagt tgcaattata cttctacgta gtatatttcg tttccatttt
     3001 cttctataag ctttttcata tcttcaaatt ttaaaaatac agtagcagta ttatcatttg
     3061 gatgtatacc tattttatcc atttttaata aatccttatc aaatacaact tttacaacag
     3121 cctctttatc atttaatata ccaaaaggag tcacagctcc tttagtaagt ttcaagtatt
     3181 tttgaagtct ttcttctgat gcaaaactaa gaggtttact atcaatttgt tgacgaatat
     3241 cttttaaatc tgcttttttg tctttaccta atacaactaa aaaatgttct tttcctttag
     3301 catcacgaag aaataggttt tttacaacaa attccatatg taatgttttt aattcttcca
     3361 tttcttcaat tgtataaact ggtggatgat ttacagcctc ataaggtatg cttaactcat
     3421 ctaatttttt atatacttcc tgttgttgat tgttcatgat ttcctcccat tagaaattta
     3481 ttttatatat aaataatatt atcacagaaa actttaaaag aaaacgtttt atataatata
     3541 gacaatagat tatattttta taaagaagca agaatactca ataaaactta aagaaattaa
     3601 acgatttcta aaaatacctt gaaaatagaa ccttatttgc catttataaa ttatataaaa
     3661 agggattata taaagtcata tatgaaaaaa ctatattata ctatcttttc tttttggaat
     3721 aaactatact ttaaatatag atatttaatt taaataaatt ttacagtatt aatagtaaat
     3781 tatcttagaa aggaatgtgc tttatatgtc tacagacaaa gttgttggaa tcatagatga
     3841 agaaacggca gaacttgcag gaattgaata tactggtaaa atttatgctt cttctggtgt
     3901 tataaaacat ataaagaaaa aacatagatg tcaactgagt aaggatattt ttaatgatat
     3961 aatagacact ataaaaatgg tattaaagtc acctgaatat ataggaagtc atcctaaaaa
     4021 acctggaaaa agtgtggagt ttataaaaaa aattgatgat tatattttag tagctacaga
     4081 attagataca aaaaaaggat atttatatgt atcttcaatg tatgctataa aagaagcaaa
     4141 attagaaagt agagtaaaca gtggaagagt aaaacaatat gatggttaac ataatattat
     4201 taattttccc taaaatattg aaaaatatta ttatataagt tataatatta atatacacgt
     4261 agatatttat tagttagatt tgaggttgga aaaggcaccc aatacgctac tatagagtag
     4321 ttaatagaga tgcaggatac gccgccctgc caaatctaat taaattaaaa agagaggatt
     4381 aattcctctc ttattgtttt tttgagatac taatttaatc tataatagaa agattgaagg
     4441 tcgtttatac aaaaaaattt tcagttatat acattaaact aattaaataa gatatttata
     4501 atctatatgt gatacatatt atatattaat aaaagaaaaa tatatagaaa atccttataa
     4561 aaatttaaat tgtaatgaat aggaagtaat taaaaagaat ttttattgat ttttaaaaat
     4621 ttagttagaa actatatcat tatggtaaaa aatgtattat aatgtttaga aatattataa
     4681 taaggagcga ttaaacatga atctatcgaa gaaaatagaa gataaaagaa aagctaaaca
     4741 gagagctgaa aaagttaaga aagctaaaat tgctacagct ggtgtggtat taggagctgt
     4801 tactggtgca gtgagtggag tacttttggc tcctaaatct ggaaaagaaa caagagagga
     4861 tataaaagat gcttcacaac aaattgctga aaagataaat atgaaaactg tagatgtaaa
     4921 aggcaaagta tctgagaagc tagaggataa aaaaggaaac tttatagaat caaagaaaaa
     4981 aataaaaaaa tatatagata acaaaaagag tgttgaaaat tctagtgagg aagataaaat
     5041 aatagatata gttgaaccag ttagtgttac tgaggaataa tatggacaat acaataacga
     5101 ttaacataag tataatatat gtattattag ctatacttgc ttgtattgct ttagtttatt
     5161 taattattgt acttgttaaa ctacataaga ttttaaataa tgttggaact atgttaaatg
     5221 aaaatactca aaatataaat acaactttaa ataatcttcc taatgttgta gaaacttttg
     5281 gagaagtagg agaaaatatg aaagatgtaa cagaagtagt tactgaagtt acagcagatt
     5341 ttcttgttac taaagacagt gtcaaatcaa atatggatgt tatagttgat atattgacta
     5401 taattaaaaa catttttgta gataaaaaat aataagttaa tataaaataa gcctataaga
     5461 tataatttaa acgaccttaa aatagcattt ataaggtcgt tttttattag cttgatttga
     5521 cactatgtgt ttttaataat tggtaatatt cctctttatc atttgaacat atatatctat
     5581 gcttgttgtt tcaattacat ccataagaac atctttacat tcaagctcaa aatcttccat
     5641 tccttctaaa tattcatcat cttcatcaaa aaagatataa gaattatata gccattcttc
     5701 aaatttttct tcaagtatat cccaatacga actccaaaat aatccacaac ctgatatata
     5761 agatgctcta ctttgattta tataaacttc atttagaagc ttttgtaatc tactgctata
     5821 aagaaaatct gctcttccac tgcttgatat taattcattt aaatcttcta ttgacattaa
     5881 ttcaacttta ccacttttat cataaggagt ataattttca tcaacccatt tatgtggttt
     5941 gttttctctg catactgttg ctatcaactc tacaactttt gttcttatca tttttttatc
     6001 ctaacttatt tattttttat aaaataatca tgattttata atttatctat ttcttgtaat
     6061 gctaatttaa cagtttcata tctatcagca ccatttatta ctacatcacc ttttacaagt
     6121 ttattagctt ctccacctac aacataaacc tttttaccta aaccttgctt ataactagac
     6181 gcttcaatta ttaaagaatc tttcaattgc caatgtaaaa tctgagcagc cactttatca
     6241 gcatcacctg tataaacgat tacattttca tacactttat tttcccctcc cccttgagaa
     6301 tttgatatag atttgtttag tataccttct gctatcaatt tagcaacttt atctttatta
     6361 ttaacataat aatctgtatc tgctttacta tctacaaaac atacttctat taatattgct
     6421 ggtgcaatag tatgattaag ccaataaaga cctctaacat cagactttgc acccctatct
     6481 ttgaatactg tagctaacct agtattcact ctttctgcat aggttttgcc attattagtc
     6541 ttatatattg tttctgtccc tactggagtt gaagttgtag catttgaatt aaaatgaatc
     6601 tgaacagcca aatcagtttc ctgtttattt gctatagcac attggtctgc taaatgatta
     6661 cttgattcat caactcttcc tgtataaaca gtagctccac ctattttaag ccatttaaca
     6721 attaagtcat tcagtattct tgtttctttg ctttcgttta tatacccaac agctcctgta
     6781 ccttttccaa ttaaagtgtg ccctggtatt attactactt tcaaactaac atctccttta
     6841 caattaaatt taacttctat ttaatatatg cataacctag aattttgttt ctttttatat
     6901 cttatacttt tattataacc cattttgtaa aaatatagaa tattaagtaa ataatgttaa
     6961 aattataatt ttgtatataa gacattactt gattgcaata attttatagc atattcatct
     7021 attctatatc cagttctata atatatatgt ttaattccag cttgaattat agccttagta
     7081 caatttaagc atggaaagtg agttacataa atagagcaat ttttaactga aataccttct
     7141 tttgcacaat aataaagggc attttgttca gcgtgaatgg ttctaataca atgtccatct
     7201 ctcatttcat gaccaacttc actacaatgc ttatctccag aaatactacc attatatcca
     7261 gtagacacta ttctgttttc tgaattgaca attatagctc ctacataagc tctatcacaa
     7321 gttcctcttt cagctactgt ttcgcacagt ctcataaaat attcttgcca tgagcatcta
     7381 ttttcaagtt ttttattcaa atcatatacc tccaaaattt atatctaata tataagattt
     7441 ataccttaaa aataatatta aaaacaaatt tatatgataa ataaaattta ttaatactgt
     7501 ttttagtcta aattatttca ttttaaatta aagttacaag gaatctaaga ttatatatat
     7561 ctttcttcgt aatatgaatg ttacaatata aaaaactgtc tcaataaaat agagacagtt
     7621 ttacagtcaa agtttataat acaagttcat atttttcttt aaattctttt acagcttcgg
     7681 gccatgcctt ttgttctgta ataccttttt ctttagctat tttaattgca atctctctta
     7741 tcattgcagc gccttctaat attcccattt ttaatctccc ttcaaatatc tttttgtata
     7801 gaatataaat agtgctaaga tttattacat gctgcatata caatatctat acaacacata
     7861 acttgtaaat tccttttatt ttcatacgtc tttaaccgac atataattat attcaataag
     7921 ttttaaaatt atgaactcaa ttataattat ttttattttt ttagaatcta aacactaaaa
     7981 attgtaggta aatttgtctt atgcctttat aaatatttct acagttttaa ttactggaca
     8041 tatctatttt tattataaaa agcgattaaa aatggagaat atcctcataa aaactatata
     8101 taagcaaaac ggttaaagga aaaagaagaa atttacttga atgttaaaat gcgttgcttg
     8161 aagcaatggg cagttttgcc tataatatcg gtaacaactg aaagaaaggt ggttagccct
     8221 aatgttaagc gaaaacatta aaacaatcag gaagtcaaaa ggactttcac aacaagaact
     8281 tgctataaaa ctgaatgtag tgcgacaaac aatatctaaa tgggaacaag gactgtcggt
     8341 tcccgattct gatatgttga tttccatatc agaggtgctt gaaacgcccg taagcacttt
     8401 acttggagaa actattgttg agtcggaagt tgataactta aaagtgattt ctgaaaaatt
     8461 agagattata aacttgcaac ttgcacaaag aaaaaacatg agaagaaaaa tgtttcattg
     8521 gttatttatt ttattatgtg cagtcatatt aatagttttt gtggtcttag ggagactaaa
     8581 tagtccttac ttggattgga attataccga ccctgaaacc gctgtttttg gagtagcttt
     8641 tcatgctttt gagtggctat ttgtcagatt agtaccgatt gtccttatag gagcaattat
     8701 tggaatcttt ttgacacgta agaaaatatg aagtaactct gctttttata atacagcaag
     8761 cgttccttaa aagcgtcatt ctacatggca atcgaggacg actatgtaag gaagaacctt
     8821 tttgatttcc aactaagcga agttattgag gacgacagta ggcccaaaac cgcattaagt
     8881 aaagtacagg aagcaagact gctggactta tactctcatg cgtcagatgc aggaaatgcg
     8941 aggtctggta gcatgattta caacgatttg tacaacgact acgagtagaa atatatggag
     9001 ataagtatta tctacgaaat cagaaaagaa atgacttgat aatttactca tgttataatt
     9061 attgatgtga aattaataaa tcgaaattcc ttttttggat ttaacaatac tgagtaagga
     9121 aaaagtgaat tacttttgca aggaggtgtt atttggatgg tgctagcagg tattttgatt
     9181 gtagtacaag gctttttgac tggtccttta gcaaaaaaaa ttggtgagaa gcgactaata
     9241 ctgataggta tgttttgcaa agccttagta gcgtttgcca tggtattgac aactgggttt
     9301 gttagtgtgt tggtggtttt tggcttattt gcggtatctt ctgctattac agtacccaca
     9361 ttaaacgcaa ccctttcaaa aactgacaat cagcataaag gaacactgat gggatttgcc
     9421 agtaccgccg gaaatcttag caaagttatt gctcctttat taactgggta tctgtatgaa
     9481 agcaatattg aattaccata tataaccacg ggagggatag ccttaatcgg agtggttatc
     9541 tgctatatct ggataaaaaa tcaaaagaac aaatgatgga agaggacgtt tatatggagg
     9601 ttatacacag taactaatct ggtatagaaa ttcaattgag gcttttctgc tttattaaag
     9661 tcttgctact acttaaccct ataatatcct taattcatta tgacaaattc caattcaaca
     9721 gttttgatac acataaggag gtaacaatac tatggaaaat tatcaatgaa gtgctaattc
     9781 tttatcagtg aagttatcca taagtttttc tacctgtaat cgtctggtgc tttttgccag
     9841 atcattggta ggtaagaaaa attcatcaac agacacatga agtaatgata caaggtcact
     9901 tgtatgcttg gatgttgccc tttattttca atattagtta agtaacgtgg gtcaatattt
     9961 gtaattcgat tttagggaaa tatttaaaga aatattttcg ttttatttct ttaaatcttc
    10021 aagaatattg atagtttttt gaaagtaggt gtgtattatg aagaatgaga aaaaaattac
    10081 agtcgcattg ctcattgttt atttattgat tttatcatgg attattttat ttaagctaca
    10141 attttcattt tctgcgttag accacataag acaaataaac ttaattcctt ttggtggttc
    10201 agttattgca aatggaaaaa ttgacttcga tgaaattata aacaatgcca ttgtttttat
    10261 ccctgtaggt gcatatttca gtttgctttt taaaaataaa tctgttctaa aagcaatagg
    10321 ttctgtttta ggaattagct ttgtatatga gataattcaa tttatatttg ctatcggagc
    10381 aagtgatatt acagacttaa ttagcaacac attagggggt ataattggaa ttgcattagt
    10441 atatgtatta tctattgttc taaaggataa aacacataag atattaaatc gaatagcaat
    10501 agtatgtact gtattagtag ttgccttctt atttatgctt cttgctgtaa ataatatatt
    10561 ttaatgccat gttaattaca tgttgttttg gaaaagactt taatctgtca aagtttgctt
    10621 ttgaaattga acatgaaatt acaccaatgg aacaaatgaa agctataaat ttttcattgg
    10681 agaaagatga ctgtacaagt aaagtattaa tatacaatcc agacaaatgg aaatatgtag
    10741 aatactattt ctataaagat agacctatta aaaaaactat tggaaaaatt tattcaattt
    10801 tgcatttgtc acaataaaat atgttttgaa atattgaata cttaaatatg caaaaaaaca
    10861 aatgtaactg gctatggggc tatatctact aaaaagctat gtgataggtt gggattaaat
    10921 ttaaacatca cttctagaag gcatgaatac acaaggctga caaactatac agttatgatt
    10981 aaacgatacc aacgggattg aaaatttcgt gaagaacttt gagaagtcct attacacatg
    11041 agcaacagca acgaagctat tgaagcaagg acgcaggcaa tctagcggtt atctgacaaa
    11101 ggagttgtag gacttgaatg tagatactat cagaacggat ataccgacca gctctgcggt
    11161 tacagatgtg attgtgtaga atatcgagca gtcgggaacg gacactttat ctgctaccta
    11221 cgaagtagat cagcagataa aagagagaga acagacaaca gcggtcaagg caacctatac
    11281 cgtaaaagtc catgtggacg ctgacgggga tatggtaatc gttcagaacc ttactcttgc
    11341 accagcaatc gaaaaatcag actatgagcc aaagatatca gaaacagacg caagcgtgga
    11401 cgctgatacc gttaatgacg ctaccgcatt tctggaaaca ttctttgagg tgtacccgac
    11461 agccacagaa aaagaacttg cctattatgt atcggaaaat gtgattgaac ctatcggcag
    11521 ggactacctt tattctgaat tggtaaaccc agtctttaca aaggacgggg acaatgtgaa
    11581 agtcaaggta gctgtgaaat tccttgataa tcagacaaag gcaacgcagg tgtcgcagta
    11641 tgatcttgta ctccaaaagg atagcaactg gaagatttta ggataacatg gaaatgggct
    11701 tgtatcataa ttatagtgtg caagcccttt tcatattgaa gtatcaataa tcaataatta
    11761 taattaggta catgaatgga gggataaaat gttcaaaatt ggtgagtttt caaaattgac
    11821 acaagtttct actcgtatgt tgcgttatta tgatgaaacg ggtttattaa aacctgctaa
    11881 aattgattca ttaactggat atcgtatgta ttcagcagaa caaatctcaa ctttaaatag
    11941 aattatatat ttacgtgata gtggcttcaa tgtcgctgaa attgcattag ccctcaattt
    12001 cagtaataat gccattatag aacagcttga tagaaagtct attgaaatta tggataatat
    12061 acaaaaagaa caagaaaaac taaagaaaat tgagattgct aaaaaagaag tgttacatgg
    12121 caaaagtgaa ttgtatttta acataaccat taaagagata ccgagttatt gcgttttatc
    12181 tttaagaaaa gaaataccaa attattatta tgagggcgaa ctctggaaag aactctctgc
    12241 ttttgctaaa gaaaataaaa taaatatttc tgatgaaaca ttctcaatat atcacaatga
    12301 agaatataaa gaaaaagatg ttgatgtaga attatgtgcc attgtaaata aaataggaaa
    12361 agctacagga gattttaagt ttcgttttac cgaaccagtt tctatgatgg cttgtactat
    12421 ggtatatgga gatttttcta atatttctta tgcttatcgt tcatttgcaa aatggcttca
    12481 agaaaacagt caatataaga tgaaaggttc aagccgtcaa atagttcatc gtggaccgtg
    12541 gaacgagaaa aatccagaga actatctaac agaaatccaa attcctttag aaaatctctt
    12601 gtaaaaaatg ataatctgcc ttgactttaa catggtgtta aggtttatcg tttatttatc
    12661 aagaagaaaa cggaggaaaa tataatgaca acttataaag taaattcaat aggtactatc
    12721 tgcaacaatg aaaaaggtgc tttcattcaa ctagaagcac catatattct agcattaagg
    12781 gcattagacg gattcagtca tataaatgtt ttatggtggt tcagtgattt tgataatacg
    12841 aattttagaa gtgtattgga aacagaacag ccttataaaa atgctccaga gaaaatgggg
    12901 atttttgcaa caaggtcgcc agtacgccca aatccgattg ctttatcagc agtagaaatt
    12961 atcgatattg attatatgag tgggctgata caaattgctt atattgacgc taatgacaaa
    13021 acgcctatct tggatattaa accatacacg ccgagtttgg atagagtgga aaatccgcaa
    13081 gttccagatt ggtgtagtca ttggcctcac agcttagaag aatctgcttc ttttgcatgg
    13141 gaaagcgaat tcaattttta aggagtgatg aaccatgagt ttgcaggact acatttttga
    13201 aaaaccagta attgaaacag aacatcttat tttaagaaca atgaataaaa atgacataga
    13261 tgatttgaaa gaatggatta gtgatatttc tttatacgag tattggggga aacgtccctc
    13321 aaaaagcgaa aaaaatccag aattactctt tgataagtca aaaaaatcta ctaaaagttt
    13381 tcattggggt attgtccata aacaagatag caaagtgatt ggtgaaatat ggatatatct
    13441 tattgaaaat aatagaatgg caaaagtggc tttcagactt tctaagcatt atcaaggtaa
    13501 tggactaatg agtgaagtgt tgaaaaacgt aattgaattt tgtttttcaa aaacagaatt
    13561 acaaaaaata tggacagatg tgcatatttt aaatcatgct tcttacaaga cattggagaa
    13621 agtcggtttt caaagggaag gacatattcg aggggggaaa atggtaaata cctattgcga
    13681 ctactaccta tatggaattt taaaatctga ttatatcact aggtggtgct atggctaata
    13741 ttgaagcgac gattggcgaa gcaatgaaca atacagttcc aaaggtctat gatacgaaaa
    13801 gcattaaaag atatgtgatg aatttattag atatggctca ttaaaaagta ccaaagaaat
    13861 aaaagttacc atatagacaa aattggtttt ttatatcttt tgatttctta taagataatg
    13921 gcattgtgcg acaagctatg caaaaaattt tcatgtatac tttgattata atttatacaa
    13981 ggaggtactg atatgtacgc atatgaaaat attgaaatgt cattaaacta tattgaacaa
    14041 catttaagtg agaaaatcga aacagagaaa ctggcggaaa ttgcctgtct ttctacattt
    14101 tattaccaac gcttgtttaa aaggttagtt aagaaatcag ttcaagagta tatcaaactt
    14161 cgccgtttag caatggtaat agcagaattg aataattcag aggaaagaat attagacata
    14221 gctttaaaat atggattttc agaccatgct aacttcacaa gagcatttaa agaagtttac
    14281 catattactc ccgatgaata cagaaagaat gttcctatgt taaatacatt tgacaagcca
    14341 gaactttctt cacgttatat catgattgat gaaaatgtcc cattgattgt aggaaatatt
    14401 gttttggaaa ttcaaagaaa aacattaaga acaaaggaaa catattttgg ttttgaaaaa
    14461 acagtaaata tttctgaaca aattcctgct ggagaaagta caggaattga tgttccaggt
    14521 cagctatggc gcgaattcca tgcaaagaaa ctgcaaaccg aaaatgccat ttttaacaat
    14581 gatattgaac ttggtgtatc tcacttagca agtccagata aaggaacatt cctttacttt
    14641 gcaggaggta tggtttcatc aacagatgta tgtcctaaaa atatggtaca acatacatta
    14701 ccagcaggtg agtatattgt atgcaaaatt gaggcagaat cttttgaaga acttgttact
    14761 actgctttaa atcaagcaaa taagtatctg tttgaaactt ggcttccaaa tcataatttg
    14821 gttacaaagc cattcatggc agaaaaatat tacaaaggaa atgcagagat taattatatg
    14881 gaaatatgga taattcctgt gtaaacagta aatgctaaat aggaattatc tgacgtaata
    14941 aaaaggaaat agaaagctta taaaggaggg catagtccgt tgtgataaac ataaaagata
    15001 taaattatgt acctaatatt agtgaaataa gcgtttatat tgaaaactct gcatttgatg
    15061 agttgtatca gcatatgaac aatgaatata aagcagtttg caaaatcgaa tacagtaaag
    15121 atgtctgggc acgaggttgg aacgtaaagt ttaaaaaatc tgggaaatca ttgtgtgttg
    15181 tctatccgaa gaagaactac tttactgtat tggtggttgt aggtaataaa gagaaagaag
    15241 atgttgaaaa cttgttacct aggctttctg aatatgtaca ggaaatttat cgtaacacta
    15301 gagagggaaa tggacaaagg tggcttatga tagacttaaa atctaaaaat aatgtatatc
    15361 aagatgtatt aaggcttatt gaaattcgtt atgccataaa atgtgtaaaa ccgtaataaa
    15421 aatatttttc acatacgtaa tctcaaggta ttatcgttga gacaagtaac ctatataatt
    15481 atgggaaatg agatttttag atacttaaga aagtacttta gggggcttgc gttatggaaa
    15541 gatttaagta caattccaca caatcaaata caatctaata aaactttact aaaaattgaa
    15601 tgcaatacag ctttaaaggc tcgtacaaac tatatgtttt gtgcgggctt ttttcattta
    15661 ataggaattt ggattcgtca gagagtatat tataaaaata aaacgataag ggtaccttaa
    15721 aaataaggta cctcaggctg tagacaaagt cccggactct cgtctgggct tttcttatat
    15781 ttgagttatc cacaattcaa ctttttaaga gttatcttat taagaaaaaa gtgtatgttt
    15841 tccaccctat agttttactt ctgtgatatt tgcagatgcc actcaagtag aaagtggtgg
    15901 tacggcagaa gatgtcatgc agagttcaga aagtctggga ctaccgccta attccttaga
    15961 cacggaaagc tcaatcaagc aggggtgtaa gtattttgcg tccctgcttt cttcctgcaa
    16021 aaatcaaggt atcgacgatt tgaatgtagc gatacaatct tacaactatg gcgggggtta
    16081 tgtgggctat gtggcaggaa aagggaaaaa gcacactttt aatcttgcag agagcttcgc
    16141 ccgtgagaaa tcgggtggaa agaaagtaac ctacgccaac ccgatagccg ttgcaaagaa
    16201 cgggggctgg cggtatggct atggaaatat gttttatgtg gaattagtca atcagtattt
    16261 aactgttccg caggtgtcgg gggaactggc acaaaaggta atgaatgaag cgttgaagta
    16321 tcaagggtgg aaatatgtgt ttgggggaag caatcccaac acttcctttg attgtagcgg
    16381 acttgtgcaa tggtgctatg gaaaagctgg tatctactta ccgagaacgg cacaaacaca
    16441 gtatgacgca acccagcata tccctttatc gcaggcaaaa gctggggagt tgttcttttt
    16501 ccattcaacc tataacgctg gttcgtatgt aac
//
LOCUS       DAJMZY010000091        16350 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.091, whole genome shotgun sequence.
ACCESSION   DAJMZY010000091 DAJMZY010000000
VERSION     DAJMZY010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16350)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16350)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16350
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.091"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            <1..369
                     /gene="tuf"
                     /locus_tag="OE968_002845"
     CDS             <1..369
                     /gene="tuf"
                     /locus_tag="OE968_002845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887863.1"
                     /note="EF-Tu; promotes GTP-dependent binding of
                     aminoacyl-tRNA to the A-site of ribosomes during protein
                     biosynthesis; when the tRNA anticodon matches the mRNA
                     codon, GTP hydrolysis results; the inactive EF-Tu-GDP
                     leaves the ribosome and release of GDP is promoted by
                     elongation factor Ts; many prokaryotes have two copies of
                     the gene encoding EF-Tu; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HCP7220108.1"
                     /translation="DNIGALLRGVQRNEIERGQVLAKTGSVKAHTKFTAEVYVLKKEE
                     GGRHTPFFDGYRPQFYFRTTDVTGACKLPEGIEMVMPGDNVTMEVDLINSIVVEEGLR
                     FSIREGGRTVASGVVATIIE"
     gene            619..768
                     /gene="rpmG"
                     /locus_tag="OE968_002846"
     CDS             619..768
                     /gene="rpmG"
                     /locus_tag="OE968_002846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004402360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HCP7220109.1"
                     /translation="MRVKVTLACTECKQRNYNTTKNKKNNPDRIELQKYCRFCKKHTT
                     HKETK"
     gene            794..1015
                     /gene="secE"
                     /locus_tag="OE968_002847"
     CDS             794..1015
                     /gene="secE"
                     /locus_tag="OE968_002847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HCP7220110.1"
                     /translation="MAAQKNDGAKTKKRFSLFGYLKETKQELKRVTWPTKKELFKNTS
                     IVLTVVISCTILVWGIDTILSGALALLLK"
     gene            1035..1577
                     /gene="nusG"
                     /locus_tag="OE968_002848"
     CDS             1035..1577
                     /gene="nusG"
                     /locus_tag="OE968_002848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination factor
                     NusG"
                     /protein_id="HCP7220111.1"
                     /translation="MSELQEASWYVVHTYSGHENKVKATIEKAVKTRGMEDCIRQVVV
                     PTEEVVETTKTGKEKTRQRKVYPSYVLVKMIITDESWYVVRNTKGVTGFVGPGSKPVP
                     LSEDEVKAMGIDTTDPKVVNSDIDFEIGDTVKVSQGPFSGQIGNIEEIDLENREVKVC
                     INAFGKRTLFVIELEGIEKI"
     gene            1616..2041
                     /gene="rplK"
                     /locus_tag="OE968_002849"
     CDS             1616..2041
                     /gene="rplK"
                     /locus_tag="OE968_002849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012158357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HCP7220112.1"
                     /translation="MAKKVIGQIKLQIPAGKATPAPPVGPALGQHGVNIMGFTKEFNA
                     KTADQAGMIIPVVITVYQDRSFSFITKTPPAAVLIKKALNLKSGSGEPNKKKVAKMTS
                     AQVREIAELKMPDLNAASVEAAMSMIAGTARSMGVVIED"
     gene            2112..2810
                     /gene="rplA"
                     /locus_tag="OE968_002850"
     CDS             2112..2810
                     /gene="rplA"
                     /locus_tag="OE968_002850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HCP7220113.1"
                     /translation="MAKKGKRYAGALQKVDRTKFYDASEALTLVSDIAGAKFDETVEA
                     HIKLGVDSRHADQQVRGAVVLPHGTGKTKRVLVFAKGEKAKEAEQAGADFVGAEELVQ
                     KIQGENWFDFDIVVATPDMMGVVGRLGRVLGPKGLMPNPKSGTVTFDVAKAIDEIKAG
                     KVEYRLDKTNIIHVPVGKVSFGGEKLTENFTALMDAIIKAKPAAAKGQYLRSITVASS
                     MGPGVKINPARTAE"
     misc_feature    2862..2990
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            3033..3539
                     /locus_tag="OE968_002851"
     CDS             3033..3539
                     /locus_tag="OE968_002851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HCP7220114.1"
                     /translation="MRKAIEIKSEVVSEIVEKLQKSSAAVVVDYKGLTVEEVTELRKQ
                     MREAGVDYKVYKNTLVRRAAKEVGIEQFNDELLVGTNAIAFGYDDPVAPARILKGFMD
                     SHPKMKLKMGIVEGAFYDESKIVEMANIPSREVLIAKLLGSLKAPVSNFAYLIDAIAK
                     KAEGQEEA"
     gene            3597..3962
                     /gene="rplL"
                     /locus_tag="OE968_002852"
     CDS             3597..3962
                     /gene="rplL"
                     /locus_tag="OE968_002852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000159736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HCP7220115.1"
                     /translation="MTIEQILEAIENMKVLELNELVKAAEEKFGVSASAPVMVAGAAA
                     GGPAAEEKTEFDVVLTDVGSSKVGVIKAVREITGLGLKEAKEVVDNAPKTVKEGASKE
                     EADQIKEKLEAAGAKVEVK"
     gene            4354..5142
                     /locus_tag="OE968_002853"
     CDS             4354..5142
                     /locus_tag="OE968_002853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HCP7220116.1"
                     /translation="MEKLQGKIAVVTAATKGIGLASAEILAKNGATVYLAARSEELAN
                     EVINKISAEGGCAKFVYFNAREEETFTSMIEEVVKKEGKIDILVNNFGSTNPSLDKDL
                     VTGDTDNFFDTVNTNLKSVYLPCKAAIPHMIKNGKGSIVNISSIGSVLPDLSRIAYCV
                     SKAAINSLTQNIATQYAKDNVRCNAVLPGLIATKAALDNMSPEFIKEFLKHVPLNRIG
                     EPDDIAKAVLFYASDDSSFITGDLLEVAGGFGLPTPQFADNILG"
     gene            5613..9329
                     /locus_tag="OE968_002854"
     CDS             5613..9329
                     /locus_tag="OE968_002854"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HCP7220117.1"
                     /translation="MPHPVTIGKRTRMSFSKIKEIADVPNLIEIQVDSYEWFLKEGLK
                     EVFDDISPIEDYTGNLILEFVDYSLDDKPKYDIEECKERDATYCAPLKVKVRLINKET
                     GEIKEQEVFMGDFPLMTERGTFVINGAERVIVSQLVRSPGVYYAEERDKTGKRLISST
                     VIPNRGAWLEYETDSNDVISVRVDRTRKQPVTVLLRALGIGTDAEIIDLLGEDERLSA
                     TLEKDNTKTVEEGLVEIYKKLRPGEPPTVESASSLLNALFFDPKRYDLAKVGRYKFNK
                     KLALCYRIMNKISAEDIINPETGEVFVKAGEKISYDLAKAIQNAGINVVNLLMDDDKK
                     VRVIGNNFVDIKSHIDFDIDDLNIKEKVHYPTLKEILDGYSDEEEIKEAIKSRIKELI
                     PKHILLDDIIASISYEFNIFYNIGNIDDIDHLGNRRIRSVGELLQNQVRIGLSRMERV
                     IKERMTVQDMEAITPQALVNIRPVSAAIKEFFGSSQLSQFMDQTNPLSELTHKRRLSA
                     LGPGGLSRERAGFEVRDVHHSHYGRMCPIETPEGPNIGLINSLGTYAKINEFGFIESP
                     YRKFDKETSTVTDEIHYLTADEEDLFVRAQANEPLTEDGKFVNHRVVCRTVNGAVEMV
                     PESRVDYMDISPKQVVSVATAMIPFLENDDANRALMGANMQRQAVPLVRREAPIIGTG
                     IEYRAAKDSGAVVVARNSGIAERVTADEIIIKREDGNRDRYNLLKFKRSNSGTCINQT
                     PIINKGDQIVKGDVIADGPATDLGEVALGRNCLIAFMTWEGYNYEDAILINERLVKED
                     RLSTIHIEEYECEARDTKLGPEEITRDIPNVGDSAIKNLDDRGIIRIGAEVDSGDILV
                     GKVTPKGETELTAEERLLRAIFGEKAREVRDTSLKVPHGESGIIVDVKVFTRENGDDL
                     SPGVNELVRCYIAKKRKIKVGDKMAGRHGNKGVISRVLPEEDMPFMENGTPLDIILNP
                     QGIPSRMNIGQVLEVHLGLAAKTLGWYVATSVFDGANEYDIMDALEEAGYPRDGKLTL
                     YDGRTGESFDNRITVGYMYYLKLHHLVDEKLHARSTGPYSLVTQQPLGGKAQFGGQRF
                     GEMEVWALEAYGAAHILQEILTVKSDDVVGRVRTYEAIVKGENIPEPGIPESFKVLIK
                     ELQSLCLDVKVLTDEDQEIEVRESVDEDDTIGEFELDVVNHMGEVEESNIIEEIEDDF
                     AENAEDEDIENLEEFTEDDLFEEEIDFDSDDFDM"
     gene            9371..12856
                     /gene="rpoC"
                     /locus_tag="OE968_002855"
     CDS             9371..12856
                     /gene="rpoC"
                     /locus_tag="OE968_002855"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HCP7220118.1"
                     /translation="MFELNNFESIKIALASPEKIRQWSRGEVKKPETINYRTLKPEKD
                     GLFCERIFGPQKDWECHCGKYRRVRYKGVVCDRCGVEVTKSKVRRERMGHIELAAPMS
                     HIWYFKGIPSRMGLLLDMSPRSLEKILYFASYVVVDPGETGLNEKQLLTEKEYRTALE
                     KYGYTFTVGMGAEAVKTLLQNIDLEQQSKDLRAELKDSTGQKKVRTIRRLEVVEAFKK
                     SGNKPEWMILDAIPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLKRLLELGA
                     PDIIVRNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSDMLKGKQGRFRQNLLGK
                     RVDYSGRSVIVVGPELKFYQCGLPKKMALELFKPFVMDKLVKEGYAHNIKSAKSIVEK
                     VKPEVWDVLEDVIKSHPVLLNRAPTLHRLGIQAFEPILVEGKAIKLHPLVCTAYNADF
                     DGDQMAVHVPLSVEAQAEARFLMLSVNNILAPKDGSPITTPSQDMVLGCYYLTIEAQD
                     GAKGTGMVFKDFNELLLAYYNKSVHLHALVKLKVTLEDGRSSLVESTVGRFIFNENIP
                     QDLGFVDRKENPFALEVDFLADKKSLGKIIDKCFRKHGNTETAELLDYIKALGFKYST
                     LGGITVAVDDMSVPEEKKVFIAEAEAKVDKYEKAYRRGLISDEERYEKVIETWTETTD
                     KVTDALMGGLDRLNNIYIMAHSGARGSKNQIRQLAGMRGLMANASGKTVEIPVKSNFR
                     EGLSVLEYFTSSHGARKGLADTAIRTAESGYLTRRLVDVSQDVIVREIDCGTEDTTEI
                     YAIKEGNEVIEEIYDRIVGRYTIDPILNPETGEVIVEADSMIQEDEAETIVALGIEKI
                     RIRTVLNCKTNHGVCSKCYGRNLATGKEVNIGEAVGIIAAQSIGEPGTQLTMRTFHTG
                     GVAGADITQGLPRVEELFEARKPKGLAVITEVSGRVEIDETGKRKEVNVIPEEGETQT
                     YVIPYGSRLKVKQGQMLEAGDPLTQGFINPHDIVRVNGVKGVQEYIVKEVQRVYRLQG
                     VDVNDKHIEVIVRQMLSKVKVEDPGDTDLLPGGYEDVLTFNECNKDAIDKGLRPAVAK
                     RVLLGITKASLATDSFLSAASFQETTRVLTEAAIKGKEDHLIGLKENVILGKLIPAGT
                     GMKKYRNIAVEKIED"
     gene            13145..13567
                     /gene="rpsL"
                     /locus_tag="OE968_002856"
     CDS             13145..13567
                     /gene="rpsL"
                     /locus_tag="OE968_002856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HCP7220119.1"
                     /translation="MPTINQLVRKSRKALEKKSTAPALQKGYNSLNKKVTDASAPQKR
                     GVCTSVKTVTPKKPNSALRKVARVRLTNGIEVSAYIPGEGHNLQEHSVVLIRGGRVKD
                     LPGVRYHILRGTLDTAGVDKRRQSRSKYGAKRPKEAKK"
     gene            13691..14161
                     /gene="rpsG"
                     /locus_tag="OE968_002857"
     CDS             13691..14161
                     /gene="rpsG"
                     /locus_tag="OE968_002857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001137493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HCP7220120.1"
                     /translation="MPRKGNIPKREVLPDPMYGSKVVTKLINNLMVDGKKGKSQRIVY
                     DAFAIVAEKTGEEALEVFNKAMDNIMPVLEVKARRVGGANYQVPIEVRPERRQTLGLR
                     WLVKYTRARGEKGMVEKLAKEIMDAANNTGASVKKKEDTHKMAEANKAFAHYRW"
     gene            14210..16276
                     /gene="fusA"
                     /locus_tag="OE968_002858"
     CDS             14210..16276
                     /gene="fusA"
                     /locus_tag="OE968_002858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HCP7220121.1"
                     /translation="MARKFPLERTRNIGIMAHIDAGKTTTTERILFYTGQTHKIGETH
                     EGASQMDWMEQEKERGITITSAATTASWKDHRINIIDTPGHVDFTVEVERSLRVLDGS
                     VAVFCAKGGVEPQSENVWRQAETYGVPRIAFVNKMDILGADFYNVVSMMKSRLNSNAV
                     PMQLPIGKEDSFIGIIDLLKMDAVIYKDDLGVEMEETDIPEDMKELAAEWREKLVESV
                     AETDEELMMKYLEGEELTIDELKVAIRKATIACEMNPVFCGTAYRNKGVQLVIDAVLD
                     YLPAPTDIPAIKGILADGEEAERHSSDEEPFSALAFKIMTDPFVGKLAFFRVYSGTLE
                     SGSYVLNATKNKRERIGRILQMHANTREEITKVYAGDIAAAVGLKDTTTGDTLCDPAN
                     PIILESMEFPEPVISVAIEPSSKAAQEKMGIALQKLAEEDPTFTVKTDQETGQTIISG
                     MGELHLEIIVDRLLREFKVEAKVGAPQVAYRETITQPVDVEYKYSKQSGGRGQYGHVK
                     IRVAPQEPGEGYKFTNKTVGGSVPKEYVGPVDMGIQGAMQSGIVAGYPVVDVAVELYD
                     GSYHEVDSSEMAFKMAGSMAFKDAMKKGNAVLLEPYFKVEVVTPEDYMGDVMGDLNSR
                     RGLIQGMEARSGAQVINAFVPLSEMFGYSTDLRSSTQGRATYTMIFDHYEQVPASVAK
                     KIAEGK"
BASE COUNT         6411 a         2033 c         3339 g         4567 t
ORIGIN      
        1 gataatatag gagcattatt aagaggagta caaagaaacg agatagaaag aggacaagta
       61 ctagcaaaga ctggatcagt aaaggcacac acaaagttta cagcagaagt atatgtactt
      121 aaaaaagaag agggtggaag acatacacca ttctttgatg gatatagacc acaattctat
      181 ttcagaacaa cagacgtaac aggagcttgt aagttaccag aaggaataga gatggtaatg
      241 cctggagata acgtaacaat ggaagtagac ttaataaact caatagttgt agaagaggga
      301 ttaagattct caataagaga aggtggaaga acagtagctt caggagttgt tgctacaata
      361 atagagtaat tctttactaa actgatggat taaaaggaat aacaaaaaga ggggttatgc
      421 tcctcttttt ttaacataga aatacaaaaa cattgacaca gcataggatt ttgtgataac
      481 ttatacaagg taatgattat aggaagttaa taatatcttg aatactgtag atttttaata
      541 aatacatatt ttaaagatat tatattcaca tatattaaca atatatatta ttgtattaca
      601 aagttggagg tgtatcagat gagagttaaa gtaactttag catgtacaga gtgtaagcaa
      661 agaaactaca acactactaa gaataagaaa aataatccag acagaataga attacaaaaa
      721 tattgtagat tctgtaaaaa gcatacaact cataaagaaa caaaatagtt ttttataagg
      781 atgtgagtat ggaatggctg cccaaaaaaa tgacggtgca aaaactaaaa aaaggtttag
      841 tttgtttgga tacttaaaag aaactaaaca agaattaaaa agagttacat ggccgacaaa
      901 aaaggaactg tttaaaaaca caagtatagt tttaactgta gttatttcat gcactatatt
      961 agtatggggt atagacacta tattatctgg tgcactagcg ttattactaa aatagacgaa
     1021 aagaggtaag ttaaatgtca gaattacaag aagcaagttg gtatgtagtt catacctatt
     1081 cgggacatga aaataaagtt aaagctacaa ttgagaaagc agttaaaaca agaggtatgg
     1141 aagactgcat aagacaagta gttgttccaa cagaagaagt agtggaaact actaaaactg
     1201 gaaaagaaaa aactagacaa cgtaaagttt atccaagtta tgttttggtt aaaatgataa
     1261 taactgatga atcttggtat gtagtaagaa atactaaggg agttacaggt ttcgttggac
     1321 ctggttcaaa accagtgcca ttaagtgaag acgaagtcaa agctatgggg atagacacaa
     1381 cagaccctaa agtagtaaat agcgatattg attttgaaat aggagataca gtaaaagtat
     1441 ctcaaggacc atttagtgga caaataggta acatagaaga aattgactta gaaaatagag
     1501 aagtcaaagt atgcataaat gcatttggta aaaggactct atttgtaata gagcttgaag
     1561 gtatagaaaa aatctaatac tatattatag aaaaatctga ggaggtgcgc tcaaaatggc
     1621 taaaaaagtt ataggtcaaa taaaattaca aatacctgca ggaaaggcta ctccagcgcc
     1681 accagttgga ccagcattag gacaacatgg tgttaatata atgggattca caaaagaatt
     1741 taatgctaaa actgcagatc aagctggaat gataatacca gttgttataa ctgtatatca
     1801 agatagatca ttcagtttta taacaaaaac tccaccagct gcagttttaa ttaaaaaagc
     1861 attaaactta aaatcaggtt ctggagaacc aaacaagaaa aaagttgcta aaatgacttc
     1921 agctcaagta agagaaatag ctgaattaaa gatgcctgac ttaaatgctg catcagtaga
     1981 agctgctatg agtatgatag ctggtactgc tagaagcatg ggtgttgtaa tcgaagacta
     2041 gttaaaagat acactttttt ttataaagtg ggaggctaga agccgaaatt aaccacgagg
     2101 aggaaaataa aatggctaaa aaaggtaaaa gatatgcagg tgcattacaa aaagtagata
     2161 gaactaaatt ttatgatgca tcagaagcat taacattagt ttcagatata gctggagcta
     2221 aatttgatga gacagtagaa gcacacatta aattaggtgt tgactcaaga catgctgacc
     2281 aacaagtaag aggtgcagtt gtattacctc atggaactgg taaaacaaaa agagttttag
     2341 tttttgctaa aggtgaaaaa gctaaagaag ctgaacaagc tggtgctgac tttgtaggag
     2401 ctgaagaatt agttcaaaaa atacaaggtg aaaactggtt tgactttgat atagtagttg
     2461 ctactccaga tatgatgggt gtagtaggta gattaggtag agtattagga cctaaaggtt
     2521 taatgccaaa ccctaaatca ggaacagtta catttgatgt agctaaagct atagatgaaa
     2581 taaaagctgg taaagttgaa tacagattag acaaaactaa cataatacac gttccagtag
     2641 gaaaagtatc atttggtgga gaaaaattaa ctgaaaactt tactgcatta atggatgcta
     2701 taataaaagc taaaccagct gctgctaaag gacaatattt aagaagtata acagtagctt
     2761 cttcaatggg acctggagtt aaaataaacc cagcaagaac agctgaataa taaaactgtt
     2821 gacacaggtt gacaaaaatg ttattatatc acttgtcaat gtaaaaaaga atagatttgc
     2881 cgtagatagt gggtgcgaaa gcttaatatc ccgccgaggt tttagataaa ttgagattac
     2941 taaagctttt gatgtctact tttggcaaca aaagcttttt ataatgttgc ggtaaatact
     3001 aagcctattt ggtgaaggag gtgcacatct atatgagaaa agctatagaa attaaatcag
     3061 aagttgtttc tgagatagtt gaaaagttac aaaaatcttc tgctgctgtt gttgtagatt
     3121 acaaaggatt aacagttgaa gaagtaactg agttaagaaa acaaatgaga gaagctggtg
     3181 tagattacaa agtatacaaa aatactttag ttagaagagc agctaaagaa gttggtatag
     3241 agcaatttaa tgatgaatta ttagttggaa ctaatgccat agcatttgga tatgatgatc
     3301 cagttgctcc agctagaata ttaaaaggat tcatggattc tcatccaaaa atgaaattaa
     3361 agatgggtat tgtggaaggt gcattctatg atgaatctaa gattgttgaa atggctaaca
     3421 taccatcaag agaagttctt atcgctaaat tacttggtag cttaaaagct ccagtatcaa
     3481 acttcgcata cttaatagat gcaatagcga aaaaggcaga aggtcaagaa gaagcttaat
     3541 tgcttaacta aaaaattata aatattaatt tgaaataaaa ttcggaggtg ctaaaaatga
     3601 caatagaaca aatattagaa gctatagaaa atatgaaagt tttagaatta aatgaattag
     3661 ttaaagctgc tgaagaaaaa ttcggtgtat cagcttcagc tccagtaatg gtagctggtg
     3721 cagctgctgg tggaccagct gctgaagaaa aaactgagtt tgatgtagta ttaactgacg
     3781 ttggttcttc aaaagttgga gttataaaag cagttagaga aataacagga ttaggattaa
     3841 aagaagctaa agaagtagtt gacaatgctc ctaagacagt taaagaagga gcttctaaag
     3901 aagaagctga tcaaataaaa gagaaattag aagctgctgg agctaaagta gaagttaagt
     3961 agtttcttta aaaagatacc cattgggtat ctttttttat ttataaaaaa ctataaagaa
     4021 agtatttgga attataaaga aagtattttt ataaaataaa aaaaatttat ataatagtac
     4081 taaattaagg gtatcatata tggtgtaatg gtattttaat ttaacattat tatcaaatta
     4141 aaatataaac aattgttgta atgtctatat ataaagtata taattaaact aaaatgtaaa
     4201 attttacatt ttagtttaaa aaaatacacg aatgttttat aaataaaatg taataaataa
     4261 ttaattaaca aatataaatt ttaaaataag ttagatattt agaaaaatcg aaatttgtag
     4321 gatttaaagg acatattcaa ggaggagtta ataatggaaa aattacaagg aaaaattgca
     4381 gtagttactg cagcaacaaa aggtattgga ttagcatcag cagagatatt agcaaaaaat
     4441 ggagcaactg tgtacttagc agctcgttca gaagaattag ctaatgaagt tataaataaa
     4501 ataagtgcag aaggtggttg tgctaagttt gtttacttta atgctcgtga agaagagacc
     4561 tttacctcaa tgatagaaga ggtagttaaa aaagaaggta agatagatat acttgtaaac
     4621 aattttggtt caacaaaccc ttctcttgac aaagaccttg taactgggga tacagataat
     4681 ttctttgaca cagtaaatac taatttaaaa agtgtgtatt taccatgtaa agcagcaatt
     4741 cctcatatga taaagaatgg aaaaggaagt atagtaaata tatcaagtat aggttcagta
     4801 ttacctgatt tatctagaat agcttactgt gtatcaaaag cagcaatcaa ctcattaact
     4861 caaaatatag ctacacaata tgctaaagac aatgttagat gtaatgctgt acttccaggg
     4921 cttattgcaa ctaaagcagc attagacaat atgtctccag agttcataaa agaattttta
     4981 aagcatgttc ctttaaatcg tataggggaa ccagatgata tagcaaaagc tgttctattc
     5041 tatgctagtg atgactcatc atttataaca ggggatttac ttgaagttgc aggaggattt
     5101 ggtttaccta ctccacaatt tgcagataat atattaggat aattaaatta ctaatatgca
     5161 atgaaagctt atgcattagt tatagtagaa atgatatttt tataaaggcc atagatataa
     5221 tttatattgg aaaggtttga ggttcaaaat tccaagttaa atttatttat ggtctttatt
     5281 ttgtatattt taataaattg tatatatttg tataaatgta attatttaca atcattttaa
     5341 tatggaatta taattaaata ggggggatgg tacttgtata aaatttttta tagaaaatta
     5401 gacctataaa tgaaaaatat ggattttata ttggaaaatt gtacataata cataatatat
     5461 gcttaaaata atttacaaaa aatcaaaaat aatgcatagt ttacatataa gataaaaaat
     5521 atattgaaaa atacttgaca ttatgctaaa attattagat gcgttagaat gaactattgt
     5581 tttattttta attattgaga ggtgaaaagt gaatgccaca tcctgtcacg ataggtaaaa
     5641 gaactagaat gagcttttct aaaattaagg aaatagctga tgtgccaaat cttatagaaa
     5701 ttcaagtaga ttcctatgag tggtttttaa aagaaggttt aaaagaagtg tttgatgata
     5761 tttcaccaat agaagattat actggtaatc ttatattgga atttgtcgac tattctctag
     5821 atgataaacc aaagtacgat atagaagagt gtaaagagag agatgctaca tattgtgcac
     5881 ctctaaaggt taaggtaaga cttataaata aagaaacagg tgagataaaa gaacaagaag
     5941 tgtttatggg tgacttccct ttaatgacag aaagaggaac tttcgttata aatggagcag
     6001 aaagagttat agtaagtcaa ttagttagat ctcctggtgt ttactatgcg gaagaaagag
     6061 ataaaacagg taagagattg atttcatcta ctgtaattcc taatagagga gcatggttag
     6121 aatatgaaac agattctaat gatgtaatat ctgtaagagt tgatagaaca agaaaacaac
     6181 cagttacagt tttacttaga gctttaggaa taggaacaga tgcagagata attgaccttt
     6241 taggagaaga tgagagatta tctgctacat tagaaaaaga taatactaag acagtagaag
     6301 aaggtcttgt agagatatac aaaaaattaa gaccaggtga acctcctact gtagaaagtg
     6361 catcatcttt attaaatgct ttattctttg acccaaaaag atatgaccta gcaaaagttg
     6421 gtagatataa attcaataag aaacttgctt tatgttacag aataatgaat aaaatttcag
     6481 cagaagacat aataaatcca gaaactggag aagtatttgt aaaagctgga gaaaaaataa
     6541 gctatgattt ggctaaagcc atacaaaatg caggtataaa tgtagtaaat ctactaatgg
     6601 atgatgataa aaaagttaga gttataggaa ataattttgt ggatattaag tctcacattg
     6661 attttgacat agatgattta aacataaaag aaaaagtaca ttatccaact ttaaaagaaa
     6721 ttttagatgg atatagtgat gaagaagaaa taaaagaggc tataaaatca agaattaaag
     6781 aacttatacc aaaacatata ttattagatg atataatagc ttcaataagt tatgagttca
     6841 atatattcta taatatagga aatattgatg atatagatca cctaggaaac agaagaataa
     6901 gatctgtagg tgaattgtta caaaatcaag ttagaattgg tctttcaaga atggaaagag
     6961 ttataaaaga aagaatgacg gttcaagata tggaagctat aacgcctcaa gcgttagtta
     7021 acataagacc agtttcagct gcaataaaag aattttttgg tagttctcag ttatctcagt
     7081 tcatggatca aacaaatcct ctatctgagt taacgcataa gagaagatta tcagcccttg
     7141 ggcctggagg tctttcaaga gaaagagctg gattcgaagt gcgtgacgtt caccattcac
     7201 actatggtag aatgtgtcca atagagactc cagagggacc aaatatcggt cttataaact
     7261 ctctaggaac ttatgcaaaa ataaatgaat ttggatttat agaatcacca tatagaaaat
     7321 ttgataaaga aacatcaaca gttactgatg aaatacatta tttaactgct gacgaagaag
     7381 atttattcgt aagagctcag gcaaatgagc cattaacaga agatggtaaa ttcgtaaacc
     7441 atagagttgt ttgtagaact gtaaatggtg ctgttgaaat ggttcctgaa agtagagtag
     7501 attacatgga tatatctcct aagcaggttg tatctgttgc cactgctatg atacctttct
     7561 tagaaaatga tgatgccaac cgtgccctta tgggagcgaa catgcagcgt caggcagtgc
     7621 ctctagttag aagagaagca ccaattatag gaactggtat agaatacaga gcagcaaaag
     7681 actctggagc agttgttgtt gctagaaatt ctggtatagc agaaagagta acagcagatg
     7741 aaataattat aaaaagagaa gatggaaaca gagatagata taatctactt aagtttaaac
     7801 gttcaaactc aggtacttgt ataaatcaaa cacctataat aaataagggt gaccagatag
     7861 taaaaggtga tgttatagca gatggtccag caactgattt aggagaagtt gcacttggaa
     7921 gaaactgtct tatagcattc atgacttggg aaggttataa ctacgaggat gctatattaa
     7981 taaatgaaag attagttaaa gaagatagat tatcaacaat tcatatagaa gaatatgaat
     8041 gtgaagctag agatacaaaa ctagggccag aggaaataac tagagatata cctaatgttg
     8101 gagatagtgc aattaagaac ttagatgaca gaggtataat aagaataggt gcagaagtag
     8161 actcaggtga tatattagtt ggtaaagtaa ctccaaaagg agaaactgaa cttactgctg
     8221 aggaaagatt acttcgtgca atatttggag aaaaggctag agaagttaga gatacttcac
     8281 ttaaagtgcc tcatggtgaa tctggtataa tagttgatgt aaaagtattt actagagaaa
     8341 atggagatga tttatctcca ggagtaaatg aattagtaag atgctatata gctaaaaaga
     8401 gaaaaataaa agttggagat aaaatggctg gtcgtcatgg taataaaggg gttatctcaa
     8461 gagtattacc tgaagaagat atgccattca tggaaaatgg aacaccacta gacataatac
     8521 ttaacccaca aggtatacca tcacgtatga acattggtca ggttttagaa gttcatttag
     8581 gacttgctgc taagacatta ggatggtatg tagcaacatc agtattcgat ggtgctaatg
     8641 agtatgacat aatggatgct cttgaagaag ctgggtatcc tagagatggt aaattaactt
     8701 tatatgatgg tagaacaggt gagtcttttg acaacagaat aactgttgga tatatgtact
     8761 acttgaaact acatcactta gtagatgaaa aactacatgc aagaagtact ggaccatact
     8821 cattagttac tcaacagcca ctaggtggta aagcacaatt tggtggacaa agatttggag
     8881 agatggaggt ttgggctctg gaagcatatg gagctgctca catacttcaa gaaatactta
     8941 ctgttaagtc tgatgacgtt gtaggtcgtg ttagaacata tgaagctata gttaaaggtg
     9001 aaaatatacc tgaaccagga atcccagaat catttaaggt tcttataaaa gaacttcaaa
     9061 gtttatgctt agatgtaaaa gtattgacag atgaagacca agaaatagaa gtaagagaat
     9121 ctgtggatga agatgataca ataggtgaat ttgagctaga tgttgtaaat catatgggag
     9181 aagttgaaga aagtaatata atagaagaaa ttgaagatga ttttgcagaa aatgcagaag
     9241 atgaggatat agagaattta gaagaattca ctgaagatga tttatttgaa gaagaaatag
     9301 attttgatag tgatgacttt gatatgtaaa tttaattaat gtaaatctca aatagaaggg
     9361 agagaactcc ttgtttgaat taaacaattt cgagtcgata aaaatagcat tggcttctcc
     9421 agaaaaaata agacaatggt ctaggggaga agttaaaaag ccagaaacta taaattaccg
     9481 tactttaaaa ccagaaaaag atggtctttt ctgtgaaaga atatttggac cacaaaaaga
     9541 ctgggagtgc cactgtggta aatatagaag agttagatat aaaggtgtag tttgtgatag
     9601 atgtggagta gaagtaacta aatcaaaagt aagaagagag agaatgggac atatagagct
     9661 agcggctcct atgtctcaca tctggtactt caaaggtata ccaagtagaa tgggactttt
     9721 acttgatatg tcaccaagat cgttagaaaa aatattatac tttgcctcat atgtggtagt
     9781 tgatccagga gagactggat taaatgaaaa acaattgctt acagaaaaag aatacagaac
     9841 tgctcttgaa aagtatggat atacttttac tgtaggaatg ggtgctgaag ctgtaaagac
     9901 attactacaa aatatagatt tagagcaaca aagtaaagac ctaagagcgg agttaaaaga
     9961 tagtacaggg caaaagaaag ttagaacaat aagaagatta gaagttgtag aggcatttaa
    10021 aaagtctgga aataaaccag aatggatgat tttagatgca ataccagtaa taccaccaga
    10081 tttaagacca atggtacaac ttgatggtgg aagatttgcg acttcagacc taaatgattt
    10141 atatagaaga gttataaata gaaacaatag acttaaaaga ttattagagc ttggagctcc
    10201 agatataatt gtaagaaatg aaaaaagaat gcttcaagaa gctgttgatg cattgataga
    10261 taatggtaga agaggtagac ctgtaacagg acctggaaat agaccactta aatctttatc
    10321 agatatgtta aaaggtaagc aaggtcgttt ccgtcaaaac ttacttggta agcgtgttga
    10381 ctactcagga cgttctgtta tagttgttgg accagaactt aaattttatc aatgtggact
    10441 tccaaagaag atggcattag aattattcaa gccatttgtt atggataaat tagttaaaga
    10501 aggttatgca cataatataa aaagtgcgaa atctatagta gaaaaagtta agccagaagt
    10561 ttgggatgtt ttagaagatg ttataaaaag tcatccagtt cttcttaacc gtgcaccgac
    10621 tctacataga ttaggtatac aagcatttga accaatctta gttgaaggta aggctataaa
    10681 actacatcct cttgtatgta cagcttataa tgcagacttt gatggtgacc aaatggcagt
    10741 tcatgtacct ttatcagtag aagcacaagc agaagcaaga ttcttaatgc tttctgtaaa
    10801 taatatactt gctcctaaag atggttcacc tataactact ccatctcagg atatggtttt
    10861 aggttgctat tatctaacaa tagaagccca agatggagct aaaggaacag gtatggtatt
    10921 taaagacttt aatgaactat tacttgctta ttacaataaa tcagttcatc tacatgcatt
    10981 agtgaaactt aaggtaacac ttgaagatgg aagaagttca ttggttgaaa gtactgttgg
    11041 tagatttata tttaatgaaa atatacctca agacttaggt tttgtagata gaaaagaaaa
    11101 tccatttgca cttgaagttg atttcttagc agataaaaaa tctcttggta aaataataga
    11161 taaatgcttt agaaaacacg gaaatacaga aacagctgaa ttactagatt atataaaagc
    11221 tctaggattt aaatattcta cattaggtgg cataacagtt gctgttgatg atatgagtgt
    11281 cccagaagaa aagaaagtat ttatagctga ggcagaagct aaagttgata agtatgaaaa
    11341 agcatacaga agaggtctaa tctctgatga agaaagatat gaaaaagtta tagagacatg
    11401 gacagaaaca actgataaag ttactgatgc tcttatgggt ggactagata gattaaataa
    11461 tatatatata atggcacatt caggagccag aggttctaaa aaccaaatta gacagctggc
    11521 aggtatgcgt ggtcttatgg caaatgcatc tggtaaaaca gttgagatac cagttaaatc
    11581 taatttccgt gaaggtttat cagtactaga atactttaca tcttcacatg gtgccagaaa
    11641 aggtcttgcc gatacagcta tacgtacagc tgaatctgga tatttaacaa gaagacttgt
    11701 tgatgtaagt caagatgtta ttgtaaggga aatagattgt ggaacagaag atactacaga
    11761 gatttatgct ataaaagaag gaaatgaagt tatagaagag atatatgata gaattgtagg
    11821 aagatatact atagacccta tattaaatcc tgaaactgga gaagttatag ttgaggctga
    11881 ttcaatgata caagaagatg aagcagaaac tatagtagct ttaggaattg aaaaaattag
    11941 gataagaaca gttcttaact gtaaaactaa tcatggagtt tgttctaagt gttatggtag
    12001 aaacttggca acaggaaaag aagttaatat aggtgaagca gttggtataa tagcagctca
    12061 atctatcggt gagccgggta ctcagcttac aatgcgtaca ttccatactg gaggagttgc
    12121 aggagctgat ataactcaag gtctaccaag ggttgaagaa ttatttgaag ctagaaaacc
    12181 aaaaggatta gctgtaataa ctgaagtatc tggtagagtt gaaattgatg aaacaggaaa
    12241 gagaaaagaa gtaaatgtaa taccagaaga aggcgagact caaacatatg taattccata
    12301 tggttctaga ttaaaagtta agcaaggtca aatgctagag gctggagacc ctctaacaca
    12361 aggatttata aatcctcatg atatagtaag agtaaatggt gttaagggag ttcaagaata
    12421 tatagttaaa gaagttcaaa gagtgtatag acttcaaggg gttgatgtta atgataagca
    12481 tatagaagtt atagtaagac aaatgctatc taaagtaaaa gttgaagacc caggagatac
    12541 agatttattg ccaggtggat atgaagatgt attaacattc aatgaatgta ataaagatgc
    12601 tatagataaa ggtctaagac cagcagttgc taaaagagtt ttacttggta taactaaagc
    12661 atctcttgca actgattcat tcttatcagc agcttctttc caagaaacaa caagagtatt
    12721 aacagaggca gcaataaaag gtaaagaaga ccacttaata ggacttaaag aaaatgttat
    12781 attaggtaag ttaataccag caggaacagg aatgaagaaa tatagaaata tagctgttga
    12841 aaaaattgaa gattaatagc atatagagta aagaaatctt gacaaccatt atttgtggtg
    12901 ttaaaatagt aaagtgtgtt gtttaaaagt acactaaggg cttgaacaag ttcttagtga
    12961 cttttagatg gcaataaatg agaactaaaa agcatcaagc tagaaaagtg ctaatatcac
    13021 atatttatgt gttatagaca ttaaattgta agtaacgaat gttacaatca gtcagtatga
    13081 atattcatat tgatgtagtt ggcggtcact gataagatcg aaaatttgga aggaggtgca
    13141 gatgatgcca acaattaacc aattagttcg taaaagtaga aaagcgctag agaagaaatc
    13201 tactgctcca gcattacaaa aaggttacaa ctctttaaat aagaaagtaa ctgacgctag
    13261 tgccccacaa aaaagagggg tttgtacttc agtaaaaaca gttactccta agaagcctaa
    13321 ctcagcttta agaaaagttg ccagagttag attaactaat ggtatagaag tttctgctta
    13381 tataccagga gaaggacaca acttacaaga gcatagtgtt gttcttataa gaggaggaag
    13441 agtaaaagac cttccagggg ttagatacca tatactaaga ggtactctag atacagcagg
    13501 tgttgataag agaagacaat caagatctaa atacggtgcg aagagaccta aagaagctaa
    13561 aaagtaaaaa caattaatga ttgattatag ttcggtgctt taaatatata tatatttacg
    13621 gcatcacggc attaaatgat ttatgtcgag tacctatgat ttaagttaaa taattaagga
    13681 gggaagcgaa atgccaagaa aaggtaatat tccaaaaaga gaagttttac cagatcctat
    13741 gtatgggagt aaggtagtta ctaaattaat aaataatcta atggtagacg gaaaaaaagg
    13801 aaagtctcaa agaatagttt atgatgcttt cgcaattgtt gctgaaaaga caggagaaga
    13861 agctttagaa gtatttaata aagcaatgga taatataatg cctgttttag aagtaaaagc
    13921 aagaagagtt ggtggggcaa actaccaagt gccaatcgaa gttagacctg aaagaagaca
    13981 aacattaggt ttaagatggc tagtaaaata tactagagct cgtggagaaa aaggaatggt
    14041 tgaaaagcta gctaaagaga taatggacgc agctaacaac actggagctt cagttaagaa
    14101 aaaagaagat actcataaaa tggcagaagc taataaagca tttgctcatt acagatggta
    14161 ggatatatag atatcttata aaattgagga tatcataagg aggataacca tggctagaaa
    14221 gtttcctttg gaaagaacta ggaatatagg aatcatggct catatagatg caggaaaaac
    14281 tactactaca gaaagaatcc tgttttatac tgggcaaact cataaaatag gagaaactca
    14341 tgaaggagct tctcaaatgg actggatgga gcaagaaaag gaaagaggta taacaataac
    14401 ttctgccgct actactgctt catggaaaga ccatagaata aacataatag atactcctgg
    14461 acacgtggac ttcacagttg aggttgaaag atctctaaga gttcttgacg gttcagttgc
    14521 tgtattctgt gcaaaaggtg gggttgagcc tcaatcagaa aatgtatgga gacaagctga
    14581 aacttatgga gtacctagaa tagcttttgt aaataaaatg gatatattag gtgcagattt
    14641 ctacaatgtt gtaagcatga tgaaatctag attaaattct aatgcagttc ctatgcaatt
    14701 accaataggt aaagaagatt catttatagg tataatagac ttattaaaaa tggatgctgt
    14761 tatatacaaa gacgacctag gggttgaaat ggaagaaaca gatataccag aagatatgaa
    14821 agaattagct gctgagtgga gagaaaaatt agttgaatca gtagctgaaa ctgatgaaga
    14881 attaatgatg aaataccttg aaggtgaaga acttactata gatgaattaa aagttgctat
    14941 aagaaaagct actatagctt gtgaaatgaa cccagttttc tgtggtacag cttatagaaa
    15001 caaaggtgtt cagttagtaa tagatgcagt tttagattac ttaccagcgc caactgatat
    15061 accagctata aaaggtatat tagcagatgg agaagaagct gaaagacatt cttctgatga
    15121 agagccattc tctgcattag cattcaaaat aatgactgac ccattcgttg gaaaactagc
    15181 gttcttcaga gtttattctg gaacattaga atcaggttct tatgttttaa atgcaactaa
    15241 gaataagaga gaaagaattg gtcgtatatt acaaatgcat gctaatacaa gagaagaaat
    15301 aactaaagtg tatgctggag atatagcagc agcagtagga ttaaaagata ctactactgg
    15361 agacacatta tgtgaccctg ctaatccaat aatacttgaa tctatggaat tccctgagcc
    15421 agttatatct gttgctatag aaccaagttc taaagcagct caagaaaaaa tgggtatagc
    15481 tcttcaaaaa ttagctgaag aagacccaac tttcacagtt aagactgacc aagaaacagg
    15541 acaaactata atatctggta tgggtgaatt acacttagag ataatagtag atagattatt
    15601 aagagaattt aaagtagaag ctaaagttgg tgcaccacaa gttgcatata gagagactat
    15661 aactcaacca gttgatgttg aatacaagta ctctaagcaa tcaggtggta gaggacaata
    15721 cggtcacgtt aagattagag ttgctcctca agagccaggt gaaggataca aattcacaaa
    15781 caaaactgtt ggtggatcag taccaaaaga atatgttggt ccagttgaca tgggtataca
    15841 aggagctatg caatctggta tagttgctgg atatccagtt gtagacgttg ctgttgagtt
    15901 atatgatggt tcttaccatg aggttgactc ttctgagatg gcgtttaaga tggctggttc
    15961 aatggcattc aaagatgcta tgaagaaagg taatgcagtt cttttagagc cttacttcaa
    16021 agtagaagtt gttactccag aagattacat gggagatgtt atgggtgact taaactcaag
    16081 aagaggatta atccaaggta tggaagctag aagtggtgca caagttataa atgcattcgt
    16141 tccactttca gaaatgtttg gatactcaac agacctaaga tcttcaactc aaggtcgtgc
    16201 aacttacaca atgatattcg atcactatga gcaagttcca gcttcagttg ctaagaaaat
    16261 agctgaagga aaataattta aaaataatta ataatataaa tataaaaaat aatcagctag
    16321 atgagagata tctctcatct agcacaagat
//
LOCUS       DAJMZY010000092        16243 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.092, whole genome shotgun sequence.
ACCESSION   DAJMZY010000092 DAJMZY010000000
VERSION     DAJMZY010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16243)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16243)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16243
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.092"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            161..679
                     /locus_tag="OE968_002859"
                     /pseudo
     CDS             161..679
                     /locus_tag="OE968_002859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888399.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            1111..1365
                     /locus_tag="OE968_002860"
     CDS             1111..1365
                     /locus_tag="OE968_002860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220122.1"
                     /translation="MENKDIKLTICIFAFVIGIIVLFCCIGLGQFNMDCIIKQNGGSI
                     ATEQYNIYLEQSISQYRNFGSILVLLGGIGILFDKSVRKY"
     gene            1401..1724
                     /locus_tag="OE968_002861"
     CDS             1401..1724
                     /locus_tag="OE968_002861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220123.1"
                     /translation="MARDVFSVKMTPLEAQKMVEKNLEADLVSVDIYNLENNKSIIVT
                     IFEKYYARSNSDAGLVVICENTTGKTLVKITSTGSAIGLFQIDWGTGNNLIKRVKKIF
                     IDYII"
     gene            1998..2150
                     /locus_tag="OE968_002862"
     CDS             1998..2150
                     /locus_tag="OE968_002862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220124.1"
                     /translation="MDNFLFNVLASVTASYIVYLISKLIKKVKSHSTAKSDLKIDINF
                     KYHRKK"
     gene            2344..3267
                     /locus_tag="OE968_002863"
     CDS             2344..3267
                     /locus_tag="OE968_002863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHOCT domain-containing protein"
                     /protein_id="HCP7220125.1"
                     /translation="MVGAFVLPNYAIILSEMSNLWGNFIMWILVPIITIVLLIIAVSS
                     MQYILVMIAFLLIIYSFIEKKIVMGLVSVLFFTYSIYLCATWEDKSLIADNKVETVKA
                     QRETVEREKEMERRRIQEEVDKERYIEKHGMEISENDLKVKLEALVPQEYKGKKYELK
                     VGKFKRYSMYFDLTVQNEKFSNSEECKKFVKEIANDLKKIKISKAYFKFHSKDDGGIY
                     NSVYIDYFRNIQNNVDNVENLEFNEFELKTEEEEKREQEKIEQEKNSYNNYIQNRVVD
                     PLDRIKKLKELLDSGAITQEEYNKKKKELLE"
     repeat_region   3534..4214
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=3534..3561
                     /rpt_unit_seq="gttttagattaactatatggaatgtaaa"
     gene            4406..4558
                     /locus_tag="OE968_002864"
     CDS             4406..4558
                     /locus_tag="OE968_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220126.1"
                     /translation="MKNRRKDKRGFSVLLDKEKLDKFDEVLEEKNLTKKEWLEEKIDE
                     ELEQKE"
     gene            4678..5492
                     /locus_tag="OE968_002865"
                     /pseudo
     CDS             4678..5492
                     /locus_tag="OE968_002865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894376.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="toxin Bro"
     gene            5544..5705
                     /locus_tag="OE968_002866"
     CDS             5544..5705
                     /locus_tag="OE968_002866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220127.1"
                     /translation="MCENLLDNMYIEKRKEEYRIKLLKIRETDIDIYNKLESIVYKLS
                     EKKLEKNNK"
     gene            complement(6034..6498)
                     /locus_tag="OE968_002867"
     CDS             complement(6034..6498)
                     /locus_tag="OE968_002867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220128.1"
                     /translation="MDFGEVKSELSDKDLKDNEEALNKYKKYYLKVYKYYSEMDSIKS
                     IQDIEIEQSRLKGQLQKNSNPIFALYISIMAVVFSTTINLTFDLSDITNYFIRMIMTL
                     LFIVLLIFLVNKGILPIAIPYRNNIQFYTTALDVLEDMKKKILRERKYKKRR"
     gene            complement(6634..6951)
                     /locus_tag="OE968_002868"
     CDS             complement(6634..6951)
                     /locus_tag="OE968_002868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220129.1"
                     /translation="MDFGNINLILIGIIVIIGTTIIYLIKPKTAFCSKKYFNKLESIY
                     GNIDKKKTVKLEVLYRYVTGLEYIAIGLFTRRLDITIIAIILVAIITTALYYLIRKKY
                     ITI"
     gene            complement(7234..7530)
                     /locus_tag="OE968_002869"
     CDS             complement(7234..7530)
                     /locus_tag="OE968_002869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220130.1"
                     /translation="MYFKTYILKREVNNKQLEITRSFDLDNLICTATEILKDNEIDLI
                     ITNEVNNVVWRNEKSTPPARECLVIAIEVYWWYTSIFLLYHINYVIKKSYLNRF"
     gene            complement(7549..7962)
                     /locus_tag="OE968_002870"
     CDS             complement(7549..7962)
                     /locus_tag="OE968_002870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220131.1"
                     /translation="MKVKSKRSFIVGIIVCMLCCASLVIYCILKDKRFLISSFLLIVI
                     AIFNFCNAFSRKGIVEELHDSADERDLYLTMKTSHILVKIMNYTLFTFTFLFIIAYSA
                     WKNQSLLVIAITLCVIEIFLFVAYLLINIFLEKKE"
     gene            complement(7946..8179)
                     /locus_tag="OE968_002871"
     CDS             complement(7946..8179)
                     /locus_tag="OE968_002871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCP7220132.1"
                     /translation="MKTKVREFRTNMGLTQQQLADLVHVSNRTIISIEKEQYSPSLML
                     AYRMAQVFGTTIEELCCLKENKEMEDKKHESKE"
     gene            8398..8772
                     /locus_tag="OE968_002872"
     CDS             8398..8772
                     /locus_tag="OE968_002872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HCP7220133.1"
                     /translation="MKISKLPEAELKVMRYICEANKVLTSRELVAAMEEKYEWNESTT
                     FTVLKRLERREFLSTEKIGKLTHYNILVKEKKYLRFETKEFLKNIHKNSISSLMSALH
                     GEDDEVDEDKLSELEEYFKNLK"
     gene            9384..10076
                     /locus_tag="OE968_002873"
     CDS             9384..10076
                     /locus_tag="OE968_002873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCP7220134.1"
                     /translation="MYNILVVDDDKEIVDSIEIYLKSEGFKIYKAYDGMKALEIITEN
                     DIHLILMDIMMPKLDGIKATVKIREERNIPIILISAKSEDTDKIIGLNIGADDYITKP
                     FNLLELIARVKSNLRRYVTLGNYEDTCKEILKSGALELNTLTKEVKIDGENIKMTPIE
                     YKIIELLLENKGRVFSIDEIYEKVWNEESFNSENTVAVHIRRIREKIEINPKEPRFLK
                     VVWGVGYKIEKF"
     gene            10272..12332
                     /locus_tag="OE968_002874"
     CDS             10272..12332
                     /locus_tag="OE968_002874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HCP7220135.1"
                     /translation="MEKYRVLKLVSLIIISISFPLTILLVTIGLAEPKYNIQKTSTKS
                     GIFDISDDFYDSNIFDEGTMASLLPKFKLSVGGKLTSKEKGKFQQEGKSIDLSSSDSE
                     YDKIMINEQASEEYLSYLKNIKVYVINTYTGVFYTNTSYASLYDFKQKTKSYCNVEII
                     NKIGKSSYIKTINGEKFELNNLSLELNEVDEGFEAYVSFPEEPTIEDGIVYTNFQIFK
                     QATEKVRLFFVASLSLAIICLLSIILYIKIKGEVLKRNNVFLLIYSKIPMEFNVILVS
                     ISIAILTIYALAVSYHIDVIALVSLSLLIVSNNIFFINVQLSYLENKMCIFKTSIIVR
                     VILWLIKTVREVSNAIKKVSLARKVIVIVIISLALIMAISTRSIGMGLLFSICIFLGF
                     TIYITKRLSYLSYVIEGTERIKKGELDYKIKITGNDNFTSLAENINNIGEGLDRAIEE
                     QVKSERMKSDLITNVSHDLKTPLTSIINYVDLIKKEESIQPEYINDYINVLESKSKRL
                     KLLIEDLFEASRVSSGNIELQISKIDLVQLLRQSIGELEEKLSKNNLYLKLNVPNDKV
                     YIWADGRRMYRVFENLLSNIAKYSLEETRVYIDVYDYGENVKVTMKNISSYELNFDPS
                     EIMERFKRADESRNTEGSGLGLAIARDLVALQGGKFYIEIDGDLFKANLEFQKYEEEI
                     TNME"
     gene            complement(12538..12861)
                     /locus_tag="OE968_002875"
     CDS             complement(12538..12861)
                     /locus_tag="OE968_002875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HCP7220136.1"
                     /translation="MNNNYIFFIIIGMYIVTYLPRVLPMLIFSKKEMPDFLKKIMKFI
                     PVAILTSLTAKDVFFNGDSLYLSIANPKIISFMIVLLVAYKFKSIGISIITGVISIYL
                     FGIIL"
     gene            complement(12854..13555)
                     /locus_tag="OE968_002876"
     CDS             complement(12854..13555)
                     /locus_tag="OE968_002876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HCP7220137.1"
                     /translation="MERTQQLKESFIASIPIFLGYIPIGIVGGILLQKSGLSPFQIAL
                     MVTLVFGGSSQFIAASMISTGASVTSIVLTTFIVNLRHFLMSSNLNMYIKNKSPKFIL
                     PFCHTITDETFAVNYEKFTAGNWSDRNAIYLNFFCLISSVLANFIGAFLGESISIDSS
                     ISGFILTSMFIALIVSQIKNKIYIVVFISSIIISVILYALFKSNLVIIVASILASLIG
                     FFIEESYCKKEESYE"
     gene            complement(13833..15218)
                     /locus_tag="OE968_002877"
     CDS             complement(13833..15218)
                     /locus_tag="OE968_002877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HCP7220138.1"
                     /translation="MPINSFENYPMNWKPKRPSKGQILYKALVEQLEQDINNGFLLPG
                     TKLPPQRELADFLDVNVSTISRAFKICEKKGLISGVTGSGTFVSYDTRSNLFLMSSNN
                     KITFIEMGTMNPDFTLEEMNTLFKHIIKEIDFKTIFQYGQRDGAKWQKEAIAKLIYKA
                     GLETTSDSLLPASGGQNAIVAILAGLFQHGDRIGVDPLTYPGIKTAAKMLGIQLIPIK
                     QEDNEISEEGLLYACKNENIKGLYIIPDYQNPTTHIMSQNGRKMIANIASKYNLIVIE
                     DAIHSLLNETHLNPVASYLPNQTIYITSLSKIIAPSLRLAYISTPKQYREALSSALYN
                     INLSQSYFLTEIAYRMITSGEADKLINARRKSARRRNKIINQYLSGYNLLGNEECIFR
                     WLILPDGIMAEKFEIQALKEGVQVYASERFAVGKEKPISAIRIAVCATESTEELKAGL
                     SVLKRLLEEKK"
     gene            complement(15664..16086)
                     /locus_tag="OE968_002878"
     CDS             complement(15664..16086)
                     /locus_tag="OE968_002878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HCP7220139.1"
                     /translation="MNTFKTEVLLKYSAKDIFNIFTKSARLNFPNFNEKKAVGTFVQQ
                     KNNKRFKVEITNFEKNRVYEIKTSNKRESTITRYELVHIDLENTKLIFIESESKRNIF
                     GKINSALVRVLFGKRQPEEFNKFIKKLEMELENNSVNL"
BASE COUNT         6446 a         1774 c         2435 g         5588 t
ORIGIN      
        1 tttaatagaa tatgtatagt atatagtaga tagaatgtat aaaaataaaa actgttcaat
       61 aagaattaat atacattaat tcagctgaat ccaatcaaaa tacttaaata aaagtaatct
      121 gaaaataaca taattcaaat caatttattc aaataaacct caatttatct caaatcttaa
      181 gaagtcatta aacaaacttg ctaaattaca aagagaatta tcaagaaaaa caatcggtag
      241 tttaaataga aataaagcaa gattaaaagt tgcaagactt caagaacata tagctaatca
      301 aagaaatgat tttctacaaa aactatctac taaattaata aaagagaacg atattatttg
      361 catagaagat ttacaagtaa agaatatgat taggaatcgt aaactatctc gctcaatttc
      421 tgatgtgtca tggtcagagt ttattcgtca attagaatac aaggctaatt ggcatggtag
      481 acaaattgta aaggtgggta aattctttgc aagttcacaa atatgcaata aatgtgggta
      541 taaaaacgag gaagtgaagg acttaaatat aagagaatgg atttatccta gttgtaatga
      601 aactcacgat agagatataa atgcaagtat aaatatatta aaagaaggat taagactaat
      661 aacaattcaa aataaataac gtatgtaaga accgtaggaa ctacggggat agcctgtgga
      721 gaattagtaa gacatatgtt agtatgcaaa attctgtgaa gcaggaaacc tgtgacttta
      781 gtcatgggag gttcaggcta gtattactca ttattgtatt caaaagctaa agtggaaacc
      841 tagtgaatat atgaatttag aagttaatga gagagcatta gcagccgact caatacttat
      901 taaaattgaa gatgaagaag aaacaatgaa agaagctgaa agagagaaaa agagaggtag
      961 aagaaggtag aatttaaagt taaaatagtt acattgctaa tatatgaaaa tgttacaaat
     1021 ttggaaatag atggatatat atgttgtata gtataatgta gataatatat caccaagtaa
     1081 aaaacaacaa ataaatctaa attatgaggg gtggaaaata aagatattaa acttacaata
     1141 tgtatatttg cttttgtaat tggaataata gtgttatttt gctgtatagg tctaggtcaa
     1201 tttaatatgg attgtattat aaaacaaaat ggtgggtcaa tagctaccga acaatacaac
     1261 atatatttag aacaatctat ttcacaatat agaaattttg gttctatact ggttttacta
     1321 ggaggaatag gaatactgtt tgataaaagt gtcagaaaat actaaaaaag tatattttta
     1381 tttaggatgt gatgaatgat atggcaagag atgtatttag tgtaaagatg acaccactag
     1441 aagcacagaa aatggtagaa aaaaatttgg aagcagattt agtttctgtt gatatttata
     1501 acctagaaaa taataagtct ataatagtta caatctttga aaaatattat gcaagaagca
     1561 atagtgatgc aggtttggta gtgatttgtg aaaatactac aggaaaaaca cttgttaaaa
     1621 ttacctcaac tggtagtgca attggactat ttcagattga ttggggaaca ggtaataatt
     1681 tgattaaaag agtaaaaaaa atatttattg attatattat ttaattattt tatgtagata
     1741 ttcttaggtt ggtatggaat ttgtactaac ctattaagta atcaataaaa ctaaataaac
     1801 atagaaagca cttacaaata tgtaggtgct ttttattgaa aaaatagaaa ataaaataaa
     1861 aagtaagata taggaaaaat atgtaagaat tatatgttat aataattgta gcaagaagat
     1921 gtaatctaca atttatagag tggagttcat gtattaaaaa attatcctcc caacgataag
     1981 aagggaggtg aatatacatg gataattttt tatttaatgt gttagctagt gtaacagcta
     2041 gttacatagt ttatttgatt agcaagttaa tcaaaaaagt aaaaagccac tctaccgcaa
     2101 agagtgactt aaagattgat ataaatttta aatatcatcg taaaaaataa ctttcagtta
     2161 tagaacttca ctctaccgca aatagattgt agttcttctt gtttttatta taccacaaat
     2221 tagaaaaaat attgcatata atatttttta tagtcaataa aaatatgaaa ttttttatac
     2281 acaatgatga tgaatctaac tagatgaata aatttaattg taaataagaa agtacttact
     2341 taaatggtag gtgcttttgt tttgccaaat tatgctataa tattgagtga gatgagtaat
     2401 ttgtggggga attttataat gtggatatta gtaccaataa taacaatagt attacttata
     2461 atagctgttt cttctatgca atatatttta gttatgatag cttttttgtt gattatatat
     2521 tcttttatag aaaagaaaat agttatgggt cttgtgtcag ttcttttttt cacttattca
     2581 atttatcttt gtgcaacttg ggaagataaa tccttgatag cagataataa agttgagact
     2641 gttaaggcac aaagagaaac tgtagaaaga gaaaaagaaa tggaaagaag aagaatacaa
     2701 gaagaagtag acaaagaaag atatattgaa aaacatggaa tggaaatatc agaaaatgat
     2761 ttaaaagtta agctagaggc tttagtacct caagaatata aggggaagaa atatgaatta
     2821 aaagtaggaa aatttaaaag atatagtatg tattttgatt taactgtaca aaatgaaaaa
     2881 tttagtaatt ctgaagaatg taaaaaattt gtaaaagaaa ttgctaatga tcttaaaaaa
     2941 attaaaataa gcaaggcgta ctttaagttt cattcaaaag atgacggcgg tatatataat
     3001 tctgtttata ttgattattt tagaaacata caaaataatg tagataatgt tgaaaattta
     3061 gaattcaatg agtttgaact taaaaccgaa gaagaagaga agcgagaaca agagaaaata
     3121 gaacaagaaa aaaacagtta taataactac attcaaaaca gagtggttga cccactagat
     3181 agaataaaga aactaaaaga gttgctagat tcaggagcaa ttacacagga agaatataat
     3241 aaaaagaaaa aagaattatt agaatagata atatagtaag cacttacaag tatgtaggtg
     3301 cttttaaatt tacaaagtat tccattttaa ttttatagtt tagattttat gatataataa
     3361 aaatatagaa gttttgcagt gtgcgatatt tgttacaaag tagggcttaa tacttgaaat
     3421 ctaagatgtt gagggtgcgt gataagtgtt atcaattgca ctattgcccg ctcactgcaa
     3481 ttttaagagt attgtatata tgtaggtatt ggaaatgcta agtttatttt ggggttttag
     3541 attaactata tggaatgtaa aactgactcg ggagcatata ataagtaata tcaagaatag
     3601 ttttagatta actatatgga atgtaaaatt cgtaaaataa caattgtcag gaatatgaga
     3661 agtttgtttt agattaacta tatggaatgt aaaattggac tcaaaatata agttaaaaaa
     3721 atttttaagt tttagattaa ctatatggaa tgtaaaaatt tttgacgcta tgaagaaatt
     3781 tactacaaaa tttgttttag attaactata tggaatgtaa aaactttttt catcctccca
     3841 aacctcttgt tcgctgtcgt tttagattaa ctatatggaa tgtaaaaaag aaaataagtt
     3901 taaaaaaagg tttcattatt atatcgtttt agattaacta tatggaatgt aaaaccaatt
     3961 atgtacagtt tagttactgt gttaagtctt gttttagatt aactatatgg aatgtaaaat
     4021 ccttttataa atatcttctg acatgtgtat atgcttgttt tagattaact atatggaatg
     4081 taaatcggct acaacggtat aaattaaatt tagcagggta cattttagat taactatatg
     4141 gaatgtaaat tgctgtgatt tcaataataa aacaattaat aattgtgttt tagattaact
     4201 atgtggattc aaaattaaat aaacaaagaa agcacttaca aatatgtagg tgcttttatt
     4261 ctgctcaaaa ttggtcggtt gggtaaaata attagaaaaa gttagtaaaa acctattgac
     4321 tgtaactcgt tacaatattg ttattaatgt aacgagttac agaaaagagg tgaataaaat
     4381 agcaactaaa agtagggcag agtatatgaa aaatcgtcga aaagataaaa gaggttttag
     4441 tgtactttta gacaaagaaa agttagataa atttgatgaa gtgttagagg aaaagaatct
     4501 aaccaagaaa gaatggctag aagaaaaaat cgacgaggaa ctggaacaaa aggaataaaa
     4561 aataagggtc actcccaccg accaaagttt gagtaacccc tatgacgtat actatcgtat
     4621 atcaattata gtatatgtca ttccttaaaa aaatcaatta ttaaggagtg taatattatg
     4681 aaaaatgaat taatgatgtt tgaaggaaaa gagattgaag tatttgaatt tgaaggaaga
     4741 attttattca actcaaaaga tgtagtaaac tgtttagaca taaaaaatgt taatgagaat
     4801 ataagactta tgaatgaaaa gcaagttgta aagttaagaa attcggatat cagtaatact
     4861 gacatccgaa aacttaataa tgctggagaa aattttctta ctgaaagtgg agtgtataaa
     4921 ttaatcttta aatcaagaaa agaagaagct gagagattcc aaggctggat aagtgatgaa
     4981 gttttaccaa gcataagaca aactggtgca tacataaata ataatgcaat accgaaaagt
     5041 tgagagaaaa agcaagtgag attgaaaaat tacagttggt ttataacagt acatctatgt
     5101 taaaagaatt gctagatgat gcaggctttg acaataaatc aaaactatta acagctaaaa
     5161 cattatataa gaaagcagga attgatttac caatagagat aaacgaagaa gaacattatt
     5221 ttgatacaaa acaaatagca tctaaactga aaatatattc taagagtaat aaaccagctc
     5281 agatggcagt ttgtgagatt attaaaaaga ttgatttaga agatggtgaa gttaaaggtg
     5341 tttgggaaat taatggttct tggactggta ctgtaaataa atatacaaag agtgtaatag
     5401 ataaggtgag aacttggata gaggaaaata atagacctac caagattgca ggtgagaaga
     5461 agaattatta tgtattttac aaaattgagt aaatttatca gttgtattaa ataatttagt
     5521 ttagttttgg ggggattaat acaatgtgtg agaatttact tgataatatg tatattgaaa
     5581 agagaaaaga agaatataga attaaacttt tgaaaataag agaaacagat atagatatat
     5641 ataataagtt agaaagtata gtatataaac tttctgagaa aaaattagag aaaaataata
     5701 aatagacata taaagcactt ggatattcta ctgtttcaag tgctttgttt ggtataaaat
     5761 ggtataatgg agatagagaa ttatattaac ccaaaaatgg agaaaataga gaagatgatt
     5821 tagttgacgc tttatcagta ggagtacttg caggtaagac agaatctcta gtactattag
     5881 ttggaaatgg aataagtgat actcaaaaaa gtttaataaa taaaagagaa tttagaaata
     5941 taactcaaat tggtggaaat ggaaatgaga aagcatttag tgaagtagaa aacttagtta
     6001 aatagattag aaggtagcaa ctagagttgg ttgttacctt ctttttttat actttctctc
     6061 tctaagtatt ttctttttca tatcttctaa tacatctaat gcagtagtat aaaattgtat
     6121 attatttcta taaggtatag ctattggaag aatgcccttg ttaactaaaa aaataagaag
     6181 tacaataaat aaaagtgtca taatcattct aataaaataa ttagtgatat ctgataaatc
     6241 aaatgttaag ttaattgttg tagaaaatac aacagccata atagatatat acaaagcaaa
     6301 aatggggtta ctattttttt gtaactgtcc tttaagccta gattgctcta tttctatatc
     6361 ttgaatactt tttatggaat ccatttcact ataatactta taaactttta aataatattt
     6421 tttatacttg tttaaagctt cttcattatc tttaaggtct ttgtcactta actctgattt
     6481 aacttcccca aaatccataa aatccctcct acaatgttat ataatatact ttaatttata
     6541 gcatatttaa gaacttatat cagcaatttg tcgaacgatt ttagctaaaa atagagtata
     6601 atgataggct tattatttat aagatattat tttttatata gttatatatt tctttctaat
     6661 tagataatat aatgctgttg ttataatggc tactaatatt attgctatta ttgtaatatc
     6721 taatcttctt gtaaataagc ctattgctat atactcaaga cctgttacat agcgataaag
     6781 tacttctagt ttaacagttt ttttcttatc tatatttcca tatattgatt ctaatttatt
     6841 aaaatatttt ttactacaaa aagcagtttt aggtttaatt aaatatatta ttgtagttcc
     6901 tattataact attattccaa taagtataag attgatattt ccaaaatcca tagcagatac
     6961 ctcctattaa atttgctttt cttaatcaaa gtatatcagt aacacaagta caaagagcat
     7021 ctaaaatatt acaaatatta acaggataga taaaactata gtaaaaattg taataataaa
     7081 gcgaacgaaa attatcatac taaaacataa gacatgttat aattgtatta gatagaagat
     7141 taacatacac caaagcactc cttacaataa agagtgctta tttttttgaa attcatcaat
     7201 atataaacta tcaagaacct tattcaacac accttaaaat cgatttaaat agctcttttt
     7261 gataacataa tttatatgat ataataaaaa aatagaagtg taccaccaat acacttctat
     7321 agctataact aagcattctc ttgctggggg agtgcttttt tcatttctcc aaacaacatt
     7381 atttacttca ttagtaatta tcaaatcaat ctcattatct ttcaaaatct ctgttgcagt
     7441 acaaattaga ttatctaagt caaaacttcg agttatctct agttgtttgt tatttacttc
     7501 tctttttagt atataagttt taaaatacat ttatatcacc ccttgtattt actctttttt
     7561 ctctaaaaat atattgataa gtaaatatgc aacaaataaa aaaatctcaa tgacacatag
     7621 tgttatagct ataactagaa gtgattgatt tttccatgca ctataagcta tgatgaaaag
     7681 aaatgtaaaa gtaaataatg tataattcat aattttaact aagatatgac ttgttttcat
     7741 tgttaagtac aagtctcttt catctgcact atcgtgtaat tcttcaacaa tgccttttct
     7801 tgaaaaagca ttacaaaaat taaagattgc tattacaatt aaaagaaatg atgaaattag
     7861 gaatctttta tcttttaaaa tgcaataaat aactaaacta gcacaacata acatacaaac
     7921 tataataccc actataaaac ttcgtttact ctttactttc atgtttttta tcctccattt
     7981 ctttattttc ttttaaacaa catagttctt caatcgttgt accaaacact tgtgccatac
     8041 gataggcaag cataagagaa gggctatatt gctctttttc aatagaaata attgttctgt
     8101 ttgatacatg gactaaatca gcgagttgtt gctgtgttag acccatattt gttcgaaatt
     8161 ctcgtacttt tgttttcatt ccataacctc tttctatatg aagctaactt catgtgaagt
     8221 tagcttcata atatcctaaa atgagtaaaa tgtcaatctc attagataag tattataaaa
     8281 cctaaaagaa taatatggta aaaattggat ggaattattt accttaattc tcttgtttgt
     8341 aaaactttat tgatatagaa tttaacatat acataaatcg gcaaaggggc gcgaattatg
     8401 aaaattagta aattaccaga agcggaatta aaagttatga gatatatttg tgaagctaac
     8461 aaggtattaa cttctaggga attagttgct gcaatggaag aaaaatatga gtggaatgaa
     8521 tcaactacat ttacagtttt gaaaagatta gagcgaaggg agtttttaag tacagagaaa
     8581 ataggcaaac ttacacatta taatatacta gtaaaagaga aaaaatatct aaggtttgaa
     8641 acaaaggaat ttttgaagaa catacataaa aattcaattt caagtttaat gtcagcgtta
     8701 catggtgaag acgacgaagt ggatgaagat aaattaagtg aactcgaaga atattttaag
     8761 aatttgaaat aagaaaatga caaattgata cataataaat aaaatgaagg tatgaaatta
     8821 taactttttc taccttcatt ttgtttatta ttctgaacat gttaagaaaa tgaaataagt
     8881 ttgtatttta gttatataaa ttttaataga atatgtacag tatatagtag atagaatgta
     8941 taaaaataga atttaaataa gtagctatta ttgcagtgaa atgaatgttt ctaagtatat
     9001 ttgggtggaa gaatggtgga agaaaattag tgaaatgtaa ttcttccacc attcttccac
     9061 ccaaaaaata aaaactgttc aataagaatt aatatacatc aattcagctg aatgcaatca
     9121 aaatacttaa atgaaagtaa tctgaaaaca acataattca aatcaattta ttcaaataaa
     9181 cctcaattta tcttaaatct taagaaatat ttaagaatta ggataatatt ttcttaagat
     9241 ttatatttta ttatatagtt ataagggaaa gttacaaaaa tgtaagccaa agtaatataa
     9301 caatttagtc attgttgaga aagggagtga aagatattgt ataatataga taagtattat
     9361 tatacaatag aggaagtgaa aatatgtaca atatattagt agtagacgat gataaagaaa
     9421 ttgttgattc gatagaaata tatcttaaat cagaaggatt taaaatatat aaagcatatg
     9481 atggaatgaa agctttggaa ataataacag agaatgacat tcatctaata ctaatggata
     9541 taatgatgcc taaattagat ggaatcaaag caactgtaaa aatacgagaa gaaagaaata
     9601 ttccaataat tttaatttca gcaaaaagtg aagatacaga taaaataata ggattaaata
     9661 ttggagctga tgattatata acaaagccat ttaatctatt agagcttata gctagggtta
     9721 aatcaaactt aagacgatat gtaactttag gtaattatga agatacatgt aaagaaattc
     9781 taaaaagtgg agctttggag ttaaatacac taacaaaaga agttaaaatt gatggtgaaa
     9841 acataaaaat gactccaatt gagtataaaa taattgaact tcttttagaa aataaaggac
     9901 gagttttctc aatagatgag atatacgaaa aagtatggaa tgaggaaagt tttaattcag
     9961 aaaatacagt agcagtacat atcagacgaa taagagaaaa gattgaaata aatccaaaag
    10021 aaccaagatt tttaaaggtg gtgtggggag ttggttataa gattgaaaaa ttttagtgga
    10081 aaaattataa aagaaaagag tttaatattt aattgcattt tgattttagt catttttaca
    10141 tttacacaaa tgttaggaat tttaatatgt tttaattttt tctctgagag tttaatttac
    10201 tctatgggga ttatgctttt cttaaacttt attttatata aaatactgac aatgtagatg
    10261 aggtgggcaa cttggagaaa tatagagtat taaagttagt ttcattaatc ataatatcta
    10321 tctcatttcc attaactata ttgttggtga caataggact tgctgagcct aaatacaata
    10381 tacaaaaaac ttctacaaag agtgggattt ttgatatatc tgatgatttt tatgatagta
    10441 atatatttga cgaaggaaca atggcaagtc tattacccaa gtttaagcta tctgtaggtg
    10501 gtaaattaac tagtaaagaa aaaggtaaat tccaacaaga aggtaaaagt atagatttaa
    10561 gtagtagtga ttctgagtat gataaaatca tgattaatga acaagcttct gaagaatatt
    10621 taagttatct aaaaaatata aaagtgtatg ttattaatac atacacagga gtattttata
    10681 caaatacgtc atatgctagt ttatatgatt ttaaacaaaa aactaagagc tattgtaatg
    10741 tagagataat aaataagata ggaaagagct catatattaa aacaataaat ggagaaaaat
    10801 ttgaactgaa taatctgagt ctggaactaa atgaagtaga tgaaggtttt gaggcatatg
    10861 tatcttttcc agaagagcca actatagaag atggaatagt atatactaat tttcaaatat
    10921 ttaaacaagc tacagaaaaa gtaagattat tttttgtagc tagtttaagt ttagcaatta
    10981 tatgtttatt atctataatt ttatatatca aaataaaagg tgaagtttta aaaagaaata
    11041 atgtattttt actaatatac agtaagatac ctatggaatt taatgtaata ttagtatcta
    11101 tttcaattgc aattttaact atatatgctc ttgctgtatc ttatcatatt gatgtaattg
    11161 cattagtttc tttatcttta ctgatagtat caaataatat attttttata aatgtgcaat
    11221 tgagctattt agaaaataaa atgtgtatat ttaagacaag tattatagta agagtgattt
    11281 tatggttaat aaaaactgta agggaggtca gtaacgctat aaagaaagta tctttagcaa
    11341 ggaaagttat tgttatagtg ataatatctt tagctttaat catggcaatt agcactcgaa
    11401 gtataggtat gggattactg ttttctatat gtattttttt aggatttaca atatatataa
    11461 ctaaaagact ttcatatctt agttacgtaa tagaaggtac agaaagaata aaaaagggag
    11521 aattagatta taagataaaa attactggga atgataattt tacgtcttta gctgaaaata
    11581 taaataatat tggagaaggt cttgatagag ctatagaaga gcaagtaaaa agtgaaagaa
    11641 tgaagtctga ccttataaca aatgtatctc atgatttgaa aactccactt acttctataa
    11701 taaattatgt agatttaatt aaaaaagaag aatcaataca accagagtat ataaatgatt
    11761 atataaatgt acttgagtca aagtcaaaaa gactaaaatt attgatagaa gatttatttg
    11821 aagcgagtag agtaagtagt ggcaatatag aattacaaat tagcaagatt gatttagtgc
    11881 aactattaag acaaagtata ggtgaacttg aagaaaaatt atctaaaaat aatttatatt
    11941 taaaattaaa tgttccaaat gataaggtgt atatatgggc agatggaaga agaatgtata
    12001 gagtatttga aaatctttta tctaatatag caaaatattc cttagaagaa actagagtct
    12061 atattgatgt atatgactat ggtgaaaatg taaaggtaac tatgaaaaat atatcttctt
    12121 atgaattaaa ttttgaccca agtgagatta tggaaagatt taaaagagct gatgaatcaa
    12181 ggaatactga aggaagtgga ttagggcttg ctattgcaag agatttagta gctttacaag
    12241 gtggaaaatt ttatatagaa atagatggag atttatttaa agcaaattta gagtttcaaa
    12301 aatatgaaga agaaataaca aatatggaat gagatagtat ttaagtatat atattttttt
    12361 tactgtcgaa agcttttatt ataatatatt agaatattta cagtagagaa tgaagagtaa
    12421 aaacagagta actttaagtc actctgtttt ttatttaaaa tcaataatat aacaacttaa
    12481 attaaaattg tacacatagt tttaaaataa cttatacaat aaaacattat ccaaatatca
    12541 caagataatt ccaaataaat atatagatat cactcctgta ataatagaaa taccaataga
    12601 tttaaactta tatgcaacaa gaagtacaat cataaaagat ataattttag ggttagctat
    12661 agataaatat agactatctc cattaaaaaa tacatcttta gcagttaagg aagtaagtat
    12721 tgctacaggt ataaatttca tgattttttt caaaaaatca ggcatctctt tttttgaaaa
    12781 aattaacata ggaagcactc ttggtagata tgtaacaatg tacattccaa ttataataaa
    12841 aaatatataa ttattattca taagattcct cctttttaca gtaagattct tctataaaga
    12901 aaccaattaa agatgctaaa attgatgcaa ctattattac taaattgctt ttgaataatg
    12961 catataaaat aacagaaata atgattgatg atataaatac tacaatataa atcttatttt
    13021 ttatttgaga aactattaaa gctataaaca tagaagtcaa tatgaagcca gaaatagaac
    13081 tgtctataga tatactttct cctaaaaatg ctccaataaa attagctaaa actgatgaaa
    13141 ttaagcagaa gaaattaaga taaatagcat ttctatcaga ccaatttcca gcagtaaatt
    13201 tttcataatt aactgcaaaa gtttcatctg ttatagtatg acaaaatggc aatataaatt
    13261 ttggactttt attttttatg tacatgttca aattagaact cattagaaaa tgtcttaagt
    13321 taactataaa tgtagtcaaa acaatagatg ttacacttgc accagtagaa atcattgaag
    13381 ctgcaatgaa ttgagaactt cctccaaata ctaaagttac cattagtgct atttgaaaag
    13441 gtgaaagacc agatttttgt aatagtattc ctcctactat acctataggt atataaccta
    13501 agaatatagg aattgaagca ataaagcttt cttttaattg ttgagttctt tccacaataa
    13561 atcactcctt ttgtattaaa tgtattaaag tattagtaaa acagaaaaat agattaattg
    13621 tataattgca attataatta aaaataaatt tggattaata tataaaatac tatacaacaa
    13681 atagataatc ttaaacggtt attaaatttt atctatttgt tattatgatg taataataca
    13741 tattaatctc tataagttaa ttactatctg gtgtaatttt attttaacaa caaaaaaaaa
    13801 tacacacaat taaaatattg tgtgcaatac aattattttt tctcttctaa tagtcttttt
    13861 aatacgctca aaccagcttt aagttcttct gtactttctg tagcacatac agctattctt
    13921 attgcagaaa ttggtttttc ttttccaaca gcaaaacgtt cagaagcata gacttgtaca
    13981 ccttctttaa gtgcttgtat ctcaaatttt tctgccatta ttccatcagg tagaatcaac
    14041 catctaaata tacattcttc atttcccaaa agattatatc cagataaata ttgattaata
    14101 atcttgtttc ttcttcttgc agatttacgg cgtgcattaa ttaatttatc ggcttcacct
    14161 gatgtaatca tgcgataagc aatttctgtt aaaaaataag attgagatag attaatgttg
    14221 tataatgcgc ttgataatgc ctctcgatac tgtttaggtg tagagatata tgctagccgt
    14281 aaactaggtg caataatttt tgataaactc gtaatataaa ttgtttgatt tggcagatag
    14341 gaagccactg gatttaaatg tgtttcatta agtaaactat gaatagcatc ctcaataaca
    14401 attaaattgt atttagatgc aatatttgca atcatttttc gtccattttg tgacattata
    14461 tgtgtagttg gattttgata atctggtatt atgtatagac ctttaatatt ttcattttta
    14521 caagcatata atagtccttc ttcactaatc tcattatctt cttgtttaat tggaattagt
    14581 tgaatcccaa gcattttagc tgctgtcttt attccaggat aagttaatgg gtctacacct
    14641 attctatctc catgttgaaa caaaccagct aaaatagcaa caattgcatt ttgtccacca
    14701 cttgcaggaa gtaagctatc tgatgtagtt tcaagcccag ctttataaat taatttggca
    14761 atagcttctt tttgccattt agcaccatct ctttgtccat attggaatat agttttaaaa
    14821 tctatttcct taattatgtg tttaaacaaa gtattcattt cttctagcgt gaaatctgga
    14881 ttcattgtgc ccatttcaat aaatgtaatt ttattattac tggacatcaa gaatagattt
    14941 gaacgtgtat cataagatac aaaagttcca cttcctgtaa ctccacttat tagacctttt
    15001 ttttcacaaa ttttaaaagc tctagagata gtactcacat taacatctaa gaaatctgcc
    15061 aattcacgtt ggggtggtaa tttagtacct ggtaataaaa atccattgtt gatatcttgt
    15121 tctagttgtt ctacaagcgc cttatataat atttgccctt ttgaaggtct ctttggtttc
    15181 cagttcatag gataattttc aaaagaatta attggcataa gttttcacct cacattatta
    15241 atttgatttt ttctttatct aaaacaataa attctaaaga tacaaataaa aactgatagg
    15301 aaataattct atcagttttt gtcttttaat tgatttcaaa tcttcctata atttttatac
    15361 cttctttatc ataaagaggg attgtttttt taaatatatt aaaatttctt tttcttgtat
    15421 ataaaacagc ttcttctggt gtctttggtt ggttatcaca atcgtacaaa tttctttttt
    15481 ttaactaaaa gcaataatac ataaaattat tattgctaat gatactctta atgtggtata
    15541 tagtcatagt gtcacatgtc tatcaatagt tttttcagta attattgtaa cgaatagtag
    15601 gactcataaa atacttagaa atatgttttt agataaattt taaatatata atctaactta
    15661 tatctataaa ttaacactat tattctccaa ttccatttct agttttttta taaatttatt
    15721 aaattcttct ggttgccttt ttccaaacaa tactcttaca agagctgaat tgatttttcc
    15781 aaatatattc ctcttgctct cactttcaat aaaaataagt tttgtatttt ctaagtcaat
    15841 atgtactaat tcatatctag taatagtact ttctctttta ttgcttgttt ttatctcata
    15901 tactctattt ttttcgaaat tagttatttc aaccttaaat cttttattat ttttttgctg
    15961 tacaaatgtt cctactgctt ttttctcatt aaaattagga aaatttagtc ttgcagattt
    16021 tgtaaatata ttaaatatgt cttttgcaga atattttaat aaaacttcag ttttaaatgt
    16081 attcatatcg ttttcccttc tgtatataaa tttaatattt ataagttaat ttttaagtta
    16141 aaatagtata atatgccata ttaaatcatg ttaaaactat ttatatagct aaaatcttac
    16201 ctatataagt atgtatacta tcatataaaa ataaaatctt aaa
//
LOCUS       DAJMZY010000093        16031 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.094, whole genome shotgun sequence.
ACCESSION   DAJMZY010000093 DAJMZY010000000
VERSION     DAJMZY010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16031)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16031)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16031
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.094"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            80..622
                     /locus_tag="OE968_002879"
     CDS             80..622
                     /locus_tag="OE968_002879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HCP7220140.1"
                     /translation="MKICITVGHSILKGGKSTGVNGIVDEYNYNKKLAPMLAEMLISQ
                     GNTVDVIICPERHFMSEREEFFYRVPKVNSGKYDLLVELHLNKADGTQCGTEVLYYGT
                     EGLEYAKRVSNRLGELFENRGAKKRENLYILRNTNPVAIQIESFFCDNVNDCNKANES
                     GYDYIARLITEGILNKDINM"
     gene            950..2443
                     /locus_tag="OE968_002880"
     CDS             950..2443
                     /locus_tag="OE968_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HCP7220141.1"
                     /translation="MKYTFEKFKLNEKILKSLKSLGYNIPSRVQREVIPKLLKGQNLV
                     VRSKTGSGKTASFAIPLCENINVDYNNIQALIVVPTRELALQVKDEISDIGRLKKVRC
                     SAIFGKQSIKDQIAELKQRVHIVVATPGRILDHINRGSIKLENVKYLVIDEADKMFNK
                     GFVEQMEKILLNLPKEKIVSLFSATIDEEIKYICEKYMLDYSVINIEENESDTNQKTR
                     QIDDKIIKANGREKYILLKELIYSENPKSVIIFCNTKEKVSKLYNKMSKEGFLIRELH
                     ADLSQERRIFVIKDFKNQKFNVLVSSDVASRGIHIDDISLVINYDVPQDKENYIHRIG
                     RTGRKGNSGKAITIVTEKDEKYIENIETYIGYKINELKDIEKSRITHGKILFEEYSKG
                     ILKKVSKRKKVDKNSYNSKDIKLNIESEVVKLYLNAGKKKKIRVLDIVGAFSNIKGIT
                     NDDIGVIEVQDLCSYVDILNYKGDLILKKYKEIPIKKKMVKVKRDIR"
     gene            2517..2750
                     /locus_tag="OE968_002881"
     CDS             2517..2750
                     /locus_tag="OE968_002881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220142.1"
                     /translation="MKAEDMKRKVSPIDLERILVTGGVIKHEDSIWLLDFWGNKDIAG
                     ILLMPPTRHVILHLNDCCKWKEYFRTKKKFYRS"
     gene            2906..3670
                     /locus_tag="OE968_002882"
     CDS             2906..3670
                     /locus_tag="OE968_002882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HCP7220143.1"
                     /translation="MAYFNYNDKQCYYNEIGDGTPLLFLHGNTASSKMFNDIIDFYKD
                     EYKVILIDFVGHGKSQMVDKFSADLWFDEAMQVICFLEAMNYKKVNIIGSSGGALVAL
                     NVALERPDLVNKVIADSFEGEVPLESFVQNVKIEREASKQDDGAKAFYIYNQGENWEK
                     VVDNDTEAIFEHYKTIGKFFHKPLETMQPEVLLTGSREDEFVSLISSDFFENTFSLLL
                     EKIKNGKMYLFDKGGHPAILSNGLDFSNVAKKFLEE"
     gene            complement(3955..7134)
                     /locus_tag="OE968_002883"
     CDS             complement(3955..7134)
                     /locus_tag="OE968_002883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HCP7220144.1"
                     /translation="MKIDMIYKLIRRNTEPSRWSRGVKYYTNQLVDYIDIDIDDLQNN
                     LLTFRGGVNSEDNYSFYFNSITIDIKHFKIIENDCSCADCQSKGKSIFICKHIVAIVI
                     KSLKQIKNKKDVPPILIDILGADKDKLSNTNSKTSLDLSKQLLSLLDNTKRERVNLDV
                     LINVDSNKAIAEFKIGIDKMYILKNITEFAYSKLNGYELDFGKKFTYNPNTHYFADED
                     EKLVDIIEEYGTNLSYNFSSSHSKKFMEINASSLKQFLNAIKYKDFTLIFSKEEYHPK
                     ILNDTLPVRFDFKNIEDKIVLYSKDSLPVPLTKKNDVLLYDGNIYLLSHKKAHDYSKI
                     YQILSKTKELKFDKEDSKDVLGLLVPRLKSISQEVHLDDNIKNNITKDFKSEFYFDMI
                     DGNICCDVKYIYDDEDKKFVLPNIQKEATIENKLTSSQFTKENNHYVFKGTDHDLFTF
                     LDLQLESLKEFGDIYYSEKFKLKKIYNASSIQASINQTNQNYLEFNFNISDINPREYK
                     DILKAFQEKRTFYKLKDGNFIDLSERETKDFFELVENLDIMDKSKNNKIHKNKALYIN
                     DVIRSKNLKFIDGKKELDSICEKFRNFDSINLEIPANLNANLRDYQINGLNWFKVLDY
                     YKFGGILADEMGLGKTIQTIAFLLSLSNKKSLIVTPTSLIYNWKNEFEKFAPDIKVLL
                     IHGNKRDREKCFMELENFDVILTTYGTLRNDLEKYSEIKFDYCILDEAQNIKNPVALV
                     TESVKSINAENKFALTGTPMENNLLELWSIFDFIMPGYLYSKAKFQELFINKEDNVKN
                     LKKLIKPFILRRSKKQVMKELPDKIEKNFFVELNKEQKKIYSVYSKDIQDKMKDKNLK
                     KDKIVIFSYLTKLRQLCLDPSIVVKDYNKKSSKIETCLEILRDSINENHKILLFSQFT
                     SVLKNISKELDKYKIKYHYIDGKTNAKERLELVDEFNNSMDKKVFLISLKAGGTGLNL
                     TSADMVIHFDPWWNPSVENQASDRAHRFGQKNSVQVIKLIAKGTIEEKIIKLQESKKE
                     LINQFINGELSNEGVLKSLSDEEIINLFN"
     gene            7415..9592
                     /locus_tag="OE968_002884"
     CDS             7415..9592
                     /locus_tag="OE968_002884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HCP7220145.1"
                     /translation="MYNKYNNLYLLLGKENVNMDSYRQLKAKIPCKETGIEIKRTLCD
                     ICSPGVHCGIDAYVKDGKVIKIEGTKEHPMNKGLLCTKGLCNREYIYREDRIKTPLKR
                     IGKRGEGKFKPISWDEAYREIAEKLNRVKSEYGAKHVAFFTGYGKWYRPFLQRFASSF
                     GSPNYGTESSSCSTSAQMAGNVATGRNFTMQDMENAKTYLGWGFNPYYSKFLNSVNLI
                     KLKEKGLKFIIVDPRITPTTQKLADLHLRIKPGTDGALALGMANLFIQKDLIDREYIE
                     KHVHGFNEYKEYVKLFDLDTVSRITGVSKDNIVKAVEMLSQGPFCINESAAPIVHHQN
                     GFQNYRAMMSLSAITGNYDRIGGNIPKQDYFAGKIGGFQTLEKEFVKEVLPKNINERI
                     GGERFPLWNEMVTQFQAMDLPRQIEEKTPYEIRALFCHGINARMFTNSGRLFKALNSV
                     DFFVNIDLFMTDTSKYADILLPACTSFEREECKSYPGGYITYTKKVIDKLYDSKSDVE
                     ILSDLANAMNIDDDLLKAGYEASIRHMFKNTCVDVDKLKESDLPLKCKDFKPYIVGSY
                     TREGYDTSTSRFELKSTIIEKYKDFGLDALPTYRGFNDNIDDEYTHLLTSGARISNAL
                     HSRLHDIKLSRILKNEASCDISSLDAKELGVISGDYIKITTKIGSLDVKVNVTDRVLY
                     KNIHMYHGYREADINSIICDNFDPYSGFPAYRSCKCKIEKMNR"
     gene            9606..10028
                     /locus_tag="OE968_002885"
     CDS             9606..10028
                     /locus_tag="OE968_002885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HCP7220146.1"
                     /translation="MKSLFKFNKELCTACGACLLACIDQNDNNIDNGELFRHVFTIEE
                     GENIEYFSLACIHCNEPKCLGVCPKNCFKKEEGFIVLDNQNCIGCKLCEKACEYGALI
                     YGNDGKANKCNGCIERYKCGMDSPCVMVCPTGALKFNK"
     gene            10436..11239
                     /locus_tag="OE968_002886"
     CDS             10436..11239
                     /locus_tag="OE968_002886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HCP7220147.1"
                     /translation="MKKLKLIIMFALVSALLVTGCSSGNNKNKEEQKVIRVATSGTYY
                     PFAFKDKDKLKGFEVDFWDEFAKRTNCKVEWVLTDFSGLFGLLEADKADVVSAQLTAT
                     PEREKKYAFSDAYNYSGTNIIVREDDTSIKSIDDLVGKKVGVGTGAVANEILKEKYPN
                     DEIKIVNYSSATLKGNYQDLEMGRLDAVVAQDVEALIAIKEQKLNLKMIEPPIQFGAC
                     SFALQKNEKGEKWTKEINEVIEEMYKDGTLTKISENWLGKDITKEPINE"
     gene            11232..11900
                     /locus_tag="OE968_002887"
     CDS             11232..11900
                     /locus_tag="OE968_002887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HCP7220148.1"
                     /translation="MSNFNFEFCLSIFPFLIKALGITILISIVAFFLSILLGVILAFF
                     TQTKSKVLQYITRVYVSFFRGTPLLIQIFFFYFGFPMIFSFMKDCSPYLAIVICLGVN
                     SSAYMAEIIRASIESVDKGQQEACYAFGLSKYQSMVKIILPQAATSAVPPIVSCTLDI
                     IKGSSLGLTIGIQDLMGVAQVEAASSFKYFEIYMITILIYWAVSIILSNIQSKVEKRI
                     RRAY"
     gene            12136..12798
                     /locus_tag="OE968_002888"
     CDS             12136..12798
                     /locus_tag="OE968_002888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HCP7220149.1"
                     /translation="MAFNMKYFLELFPTIMKSFNVTVILAISSLVFSLIIGTIVALSS
                     YYKVKVLNQICKVYVSIFRGTPLMPQLFFLYFGLAYMSDFVKNMDPVFATSIVLSLNM
                     GAYMSETIRASILSIDTGQIEAAYAMGLTNLQTMKRIVIPQAVRVALPSLFNNFIDLI
                     KGSSVAFVVGVNDIMGAAKSQGALSFKFFEVYGAVMVIYWCIITPLGWGQKKLEKKIS
                     NY"
     gene            12858..13655
                     /locus_tag="OE968_002889"
     CDS             12858..13655
                     /locus_tag="OE968_002889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HCP7220150.1"
                     /translation="MIKRNIIKCLVAVLSLTFVITGCSKKEEVKNEKVITVASSNSAD
                     PYSYVDNGEHKGFEVDMWKEIGKRSGYKIKMEPTGFSSIFGMLDSGKVDVAANFFGMS
                     KERLEKYDASIPYGSDSVCIAVKDGNNEINKLEDLKGKVVAVSEGSQGQQVATSVNKD
                     NLFQEKVYGDGTSGLQDLDLGRVSAWIDAELTIVGDAKKANMKVRVLDKKLSATNIAY
                     FFKKNDDKSKTIKEDVNKAIEEMLADGTVKKISEKWFGMDVSADIQK"
     gene            13773..14963
                     /locus_tag="OE968_002890"
     CDS             13773..14963
                     /locus_tag="OE968_002890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HCP7220151.1"
                     /translation="MEVLQMIETKIKSIALKNREKIIKIRRQIHSNPELAFKEYKTSK
                     LIKEELNKLNIEYINIAGTGVLATIKGKNNGGKTILLRADMDALPIKEENDLEFKSIN
                     DNMHACGHDAHVSWLLGTAMILNDIKEELNGNVKLLFQPGEEKGGSDIVIKENVLEGV
                     DALATGHCWPTIESGKIGIARNCAMAATNTFEITIIGKGGHGAEPHNCIDPIAVGNAV
                     YSSIQQIVSRKIDPVVPVVVSVCSFNSGVSKNIIPDVCTLQGTIRAISKEQVIEVSKI
                     LEYIVKNVCKAHGADCKFEKSTGGDAVINDKNMIEIGRESACKILGAENVEIIDFPAM
                     TGEDFAIYMKEKPGLFMYIGVGDKEKNINYRLHSNKFNIDEKCLSIAPSLFSQLTVDY
                     LCQL"
     gene            15072..15821
                     /locus_tag="OE968_002891"
     CDS             15072..15821
                     /locus_tag="OE968_002891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HCP7220152.1"
                     /translation="MIKVENLHKSFKGTEVLKGINLEISQSEVVAILGSSGTGKSTLL
                     RCLNYLVEPTKGKIMIGDVKVDVEKATKKDITNLRKHTSMVFQNYNLFKNKTALENVM
                     EALIVVHKKSKKEAREISLKLIDKVGMLDRKDFYPSKLSGGQQQRIGIARAMAVNPNV
                     ILFDEPTSALDPELVGEVLSVIKSLAKEGITMLIVTHEINFAKEVADKIIFMDNGVIA
                     EEGTPDEIFNNPKNERTAKFLNIIRKEEVFS"
BASE COUNT         6232 a         1678 c         2650 g         5471 t
ORIGIN      
        1 atatattatt attagtaata actttaaaat tatattacta ttatataaaa attggcttaa
       61 aagaaggtga aaaaagtaaa tgaaaatatg cataacagta ggtcatagta tactaaaagg
      121 tggtaaaagt acaggtgtaa atggtatagt tgatgaatac aattataata aaaaattagc
      181 tcctatgtta gctgagatgc ttataagtca aggtaataca gtagatgtaa taatttgtcc
      241 agaaaggcac tttatgtcag aaagagaaga atttttctat agagttccaa aagtaaacag
      301 tggtaaatac gatttattag tagagctaca tttaaataaa gctgatggaa cacaatgtgg
      361 tacagaagtg ctttactatg gcactgaagg attagaatat gctaaaagag tatctaatag
      421 acttggagaa ttatttgaaa atagaggagc taaaaaaaga gaaaatttat atatattgag
      481 aaatacaaat ccagttgcaa tacagattga aagttttttc tgtgataatg tgaatgattg
      541 taacaaagca aatgaatcag gttatgatta tatagcacga ttgattacag aaggtatatt
      601 gaataaagat ataaatatgt gagattatgg tgatttaggt attgattaat accttttaat
      661 attagatata aataaaaata caatgtatta gtataattta aactttcaaa agatagatta
      721 gtttgattat tgacaagaga tacctccttg aaaatattga tttatcagta tatttaagga
      781 ggtatttaaa tataaaaatt taattaattt gctactaaac tataggttta tagagtatat
      841 atttttatct tcagtctaat aaataatata aaaatagtag aaccttgtat tataataata
      901 taatgtagaa aaatatatag ataagataaa tataataagg tggtaatata tgaaatatac
      961 atttgaaaaa tttaagttaa atgaaaagat acttaagtca ttgaagagtt taggatataa
     1021 tataccttct agagtacaaa gagaagttat tccaaaatta ttaaaaggtc aaaacttagt
     1081 agttaggtca aaaacaggaa gtggaaagac agcaagtttt gcaatacctt tatgcgagaa
     1141 tataaatgta gattacaata atattcaagc tcttatagtg gttccaacaa gagaattagc
     1201 cttgcaagta aaagatgaga tatcagatat agggagacta aagaaggtga gatgtagtgc
     1261 tatatttggt aaacaatcta taaaagacca aatagctgaa ttgaaacaaa gggttcatat
     1321 tgttgtagct actccaggca gaatacttga ccatataaat agaggttcta ttaagttgga
     1381 aaatgtaaag tatttagtaa tagatgaggc agataaaatg tttaataaag gttttgttga
     1441 acaaatggaa aaaatattat taaatttacc taaggagaaa atagtaagtc ttttttcagc
     1501 tacaatagat gaagagataa aatatatatg tgaaaaatat atgctagatt acagtgttat
     1561 aaatatagaa gaaaatgaga gcgatactaa tcaaaaaaca agacaaatag atgacaaaat
     1621 aatcaaggca aatggaagag agaagtacat ccttttaaaa gaattaatat acagcgaaaa
     1681 tccaaagagt gtgataatat tttgtaatac caaagagaaa gtatctaaat tatataacaa
     1741 gatgagtaaa gaaggttttt taataagaga gttacatgca gatttatcac aagaaagaag
     1801 aatttttgta attaaggatt ttaaaaacca aaaatttaat gtattagtta gtagtgatgt
     1861 agcgtccaga ggaatacata ttgatgatat ttctttagta ataaattatg atgtgccaca
     1921 agataaagaa aactatatac atagaatagg tagaactggg agaaaaggaa atagtggaaa
     1981 ggcaattact atagtaactg aaaaggatga aaaatatata gagaatatag aaacgtatat
     2041 aggatataaa ataaatgaat taaaagatat agaaaaaagt agaattacac atggcaaaat
     2101 tttgtttgaa gaatattcaa aaggaatcct aaaaaaagta tcaaagagaa aaaaagttga
     2161 taaaaattct tacaatagta aagatataaa actaaatata gaaagtgaag ttgttaaatt
     2221 atatttaaat gctggtaaga agaagaaaat aagagtttta gatatagttg gtgcatttag
     2281 taatataaaa ggtataacta atgatgatat aggtgtaatt gaagttcaag atttatgttc
     2341 atatgtagat atattaaatt ataagggaga tttgatatta aaaaaatata aggagatacc
     2401 tataaagaaa aaaatggtta aagtgaaaag agatatacga taatttagtc aatattgatg
     2461 aattgctttg ttatcgaaat gaagttgcaa aaaacacaat agaagttgtt aaggatttga
     2521 aagctgaaga tatgaaacga aaggtctctc caattgactt agaaaggatt ttggtgactg
     2581 gaggagtaat aaagcatgaa gattctattt ggttgttgga cttttggggg aataaagata
     2641 ttgctggaat tttgcttatg cctcctactc gtcatgttat acttcatttg aatgattgtt
     2701 gtaaatggaa ggaatatttt cgtacaaaaa agaaatttta cagaagttaa attataataa
     2761 attagacaaa caatagataa attagcaagg aatgttgatt ttatctacat tctaagttat
     2821 actattttta agtggctaat ggaatagtca ttttaaatat aagtaataaa tatataccta
     2881 tagggatatt aaagggggga aatatatggc atattttaac tataacgaca aacagtgcta
     2941 ctataatgaa attggggatg gtacaccatt acttttttta catggaaata cagcctcttc
     3001 caagatgttt aatgatataa tcgattttta taaagatgaa tataaagtaa tattaattga
     3061 ttttgtaggt catggaaaat ctcaaatggt cgataaattt tctgctgact tatggtttga
     3121 tgaggctatg caagtgatat gttttttaga agcaatgaac tataaaaaag taaacataat
     3181 tggtagtagt ggaggagctc ttgttgcatt aaatgttgca cttgagagac ctgatttagt
     3241 gaataaggta attgcagata gttttgaagg agaagttcct ctagagtcat ttgtacaaaa
     3301 tgtgaaaata gagcgtgaag catctaagca agatgatggt gcaaaagctt tttatattta
     3361 taatcaagga gaaaactggg aaaaagttgt agataatgat acagaagcta tttttgaaca
     3421 ttataaaact ataggaaaat tttttcataa gcctctagaa actatgcaac cagaggtgct
     3481 tttaacagga agtagagaag atgagtttgt atctctaata tctagtgatt tttttgaaaa
     3541 tactttttca ttacttcttg aaaagattaa aaatggtaaa atgtatttgt ttgataaagg
     3601 tggtcatcct gcaattttat cgaatggatt agatttttca aatgtagcaa agaaattttt
     3661 agaggaataa tttaaccaaa atttataata atgaaaactg taaaatggat tgcaaaactt
     3721 acaaaagtga gtgtacatat acttcattat tatgatgaaa tagtattgtt aaaacaaaat
     3781 attctaatag tcaagttatt acatttgtat atgcaatatg tatagaaaga gatatcatta
     3841 gattgtaaag ttgggattaa ataacaatat taaattttat ttattcagat attttagctt
     3901 aactatataa atgttagaac aaatttatat agttaagctg taggattaaa taatttagtt
     3961 aaataagttt attatctcct catcagatag actttttaat acaccttcat tagaaagttc
     4021 tccatttata aattgattta taagctcttt tttactttct tgtaatttta ttattttttc
     4081 ttctatagtc cctttagcaa tcaattttat aacttgtact gaattttttt gaccaaatct
     4141 atgagctcta tcactagctt gattttctac tgatggattc caccatgggt caaagtgaat
     4201 taccatgtca gcagatgtaa gatttaaacc agttccgcct gcttttaaag atattaaaaa
     4261 aactttttta tccatactat tattgaactc atctacaagt tcaagtcttt ctttggcatt
     4321 agttttacca tctatataat ggtatttaat tttatactta tcaagttcct tacttatgtt
     4381 cttaagcaca gaagtaaatt gtgaaaacaa taatattttg tggttttcgt ttatactatc
     4441 cctaagtatt tctaaacatg tttcaatttt tgaacttttt ttattgtaat cttttactac
     4501 tatacttggg tctaaacaaa gttgtcttag tttagttaaa taagaaaata taactatttt
     4561 atctttcttt agatttttat ctttcatttt atcttgtata tcttttgaat atacactata
     4621 tatctttttc tgctctttat tcaattcaac aaaaaagttt ttttcaatct tatctggaag
     4681 ttctttcata acttgttttt tacttcttct aagaataaaa ggttttatca attttttcag
     4741 gtttttaaca ttatcttctt tatttataaa caattcctga aactttgctt tactatatag
     4801 atagccaggc attataaaat caaatataga ccataattct agtagattat tttccatagg
     4861 tgtaccagtg agtgcaaatt tattttctgc atttatactt tttacagact cagttactaa
     4921 agctactgga ttttttatat tttgagcttc atctaatata caataatcaa actttatttc
     4981 actatatttt tctaaatcat ttctaagagt accatatgtt gtaagtatta catcaaaatt
     5041 ttctaattcc ataaaacatt tttctctatc tcttttattt ccatgtatca ataaaacttt
     5101 tatatctgga gcaaactttt caaattcatt tttccaatta taaatgagtg atgtcggtgt
     5161 aacaataaga ctttttttat tagataatga taataaaaat gcaatagtct gtattgtttt
     5221 accaagaccc atttcatcag ctaatatacc accaaattta taataatcta aaactttaaa
     5281 ccaattgagg ccatttattt gatagtcacg aaggtttgca tttaaatttg cgggaatttc
     5341 taaatttatg ctatcaaaat ttctaaattt ttcacatata ctgtctagtt cttttttacc
     5401 atctataaac tttaaatttt tactacgtat tacatcattt atatatagag ctttattttt
     5461 atgaatttta ttattttttg atttatccat tatatctaga ttttcaacta attcaaaaaa
     5521 atcttttgtt tctctttctg ataaatctat aaagtttcca tctttaagtt tataaaaagt
     5581 acgtttttct tgaaaagctt tcaaaatatc cttgtactct cttggattta tatcagatat
     5641 attaaaatta aattctaggt aattctggtt agtctgattg attgaagctt gaattgatga
     5701 agcgttatat atttttttca atttaaactt ctcagaataa tatatatctc caaattcctt
     5761 tagagattct aattgtaaat ctaaaaatgt aaataggtca tggtcagttc ctttaaacac
     5821 ataatgatta ttttcctttg taaattgtga agaagtaagt ttattttcaa tagtagcttc
     5881 cttttgtatg ttggggagca caaatttttt atcttcatca tcatatatat actttacatc
     5941 acaacatatg ttgccatcaa tcatatcaaa gtagaactca gatttaaaat cttttgttat
     6001 attatttttt atgttatcat ctaaatgaac ttcttgagat atagatttta atctaggaac
     6061 tagcaatcct aaaacatcct tagaatcctc tttatcaaat tttaactctt tagtctttga
     6121 taatatttga tatatttttg aataatcatg agctttttta tgtgataata aatagatatt
     6181 gccatcatat aaaagtacat catttttttt agtaagtgga acaggtagtg aatctttaga
     6241 atataagact attttatctt ctatattttt aaaatcaaac cttacaggta gagtatcatt
     6301 taatatcttt ggatgatatt cctctttaga aaaaataagg gtaaaatcct tgtacttaat
     6361 agcatttaaa aattgtttta aagagcttgc atttatctcc ataaattttt ttgaatgtga
     6421 tgaagaaaag ttgtatgaaa gatttgtccc atattcttct ataatatcta ctaacttctc
     6481 atcttcatca gcaaaataat gagtgttggg gttgtaagta aatttcttcc caaaatctaa
     6541 ttcatatcca ttaagttttg aatatgcaaa ttcagtaatg ttttttaaaa tgtacatttt
     6601 atcaattcct attttaaatt cagcaattgc tttatttgaa tccacattta tcaatacatc
     6661 taaattaacc ctttctcttt tagtattgtc taacaaagaa agtaattgct tgcttaaatc
     6721 taagctggtt ttagaatttg tattagaaag cttatcctta tctgcaccta atatatctat
     6781 tagaatagga ggaacatctt ttttattttt tatttgtttt aagcttttta tcacaatagc
     6841 aactatatgc ttacatataa aaatactttt gccctttgat tgacagtcag cgcaactaca
     6901 atcattttca attatcttaa agtgctttat atctatagtt attgaattaa aataaaagct
     6961 ataattatct tcagaattga ctccaccacg aaatgtcaac aggttatttt gtaggtcatc
     7021 aatatctatg tctatataat caactaattg attagtataa tattttacac ctcttgacca
     7081 tcttgatggt tctgtatttc ttcttattag tttatatatc atatctattt tcatattatt
     7141 caccttacct cactgtatat attataatct aaatgcattc aatttacact ctaaatttaa
     7201 gactaaaatt aaggcagata tgaatagctt ttatctatca caatatatgt gtaaataaca
     7261 atttactatt agatttttat tgaattatct tataaactat gaatgaaaaa taattatata
     7321 aatagattat taataaatat aaaatcttat tattaaaaat attcttagaa attacactat
     7381 ataaaatata aagtatgata tttgaataaa aagaatgtat aataagtata ataatttgta
     7441 tttattattg ggaaaggaaa atgttaatat ggatagttat agacaactta aagctaaaat
     7501 accctgtaag gaaacaggta tagaaataaa gaggacttta tgtgatattt gttctccagg
     7561 agtacattgt ggaattgatg catatgttaa agatggtaaa gtaataaaaa tagaaggtac
     7621 aaaagaacat ccaatgaata aagggttgtt atgtaccaaa ggtctttgca atagagaata
     7681 tatctataga gaagatagaa taaaaacacc tctaaaaaga attggaaaaa gaggtgaagg
     7741 aaaatttaaa ccaatatcat gggatgaagc ttatagagaa atagcagaaa aattaaatag
     7801 agtaaaatct gagtatggag caaagcatgt agcttttttt acgggttatg gaaagtggta
     7861 tagacctttt ttacaaaggt ttgcatcttc atttggttca cctaattatg gtacagaatc
     7921 tagttcatgt tcaacatcag cacagatggc tggaaatgtt gctactggaa gaaactttac
     7981 aatgcaagat atggagaatg caaaaactta tttagggtgg ggatttaatc catactactc
     8041 taaattttta aatagtgtga atctaataaa attaaaagaa aaaggtctaa aatttataat
     8101 tgtagaccct agaataacac cgacaactca aaaactagca gatttacatt taagaattaa
     8161 acctggaact gatggagctt tagctcttgg aatggcgaat ctatttatac aaaaggattt
     8221 aatagataga gaatacatag aaaagcatgt acatggattt aatgaatata aagaatatgt
     8281 aaaattattt gatttagata ctgtaagtag aattacagga gtttctaaag ataatatagt
     8341 aaaagctgtc gagatgttgt cacaaggtcc attttgtata aatgaaagtg cagctccaat
     8401 agttcaccat caaaatggat ttcaaaatta tagagcaatg atgtctttat ccgctataac
     8461 aggtaattat gatagaatag gtggaaacat accaaaacaa gattactttg ctggtaagat
     8521 aggtggattc caaacactag aaaaagagtt tgtaaaagaa gttctaccta aaaatataaa
     8581 tgaaagaatt ggtggagaaa gatttcctct atggaatgaa atggtgactc aatttcaagc
     8641 tatggattta cctaggcaaa tagaagaaaa gacaccatat gaaataagag ctttgttttg
     8701 tcatgggata aatgctagaa tgtttactaa ttcagggaga ctttttaaag cgttgaatag
     8761 tgtagatttt tttgtgaata tagatttatt tatgacagat acatcaaaat atgcagatat
     8821 acttttacct gcatgtacat catttgagag agaagaatgt aagagttatc caggagggta
     8881 tattacatat accaaaaaag ttattgataa attatacgat tcaaaatcag atgtagaaat
     8941 actttcagat ttagcaaatg ctatgaatat agatgatgat ttattaaaag caggttatga
     9001 agcaagtata agacatatgt ttaaaaatac atgtgtagat gtagataaac ttaaagaaag
     9061 tgatttacca ttaaaatgta aagattttaa gccatatata gtaggttcat atacaagaga
     9121 agggtatgat actagcactt ctaggtttga attaaaatct acaattattg aaaaatataa
     9181 agattttggg ctggatgcac taccaacata tagaggattt aatgataata tagatgatga
     9241 atatactcat ttattgacat caggagcaag aatttcaaat gcactacatt caagacttca
     9301 tgacatcaaa ctttcaagaa tattaaaaaa tgaagctagt tgtgatattt ctagcttaga
     9361 tgcaaaagaa ttgggtgtta tcagtggaga ttatataaaa ataactacta agataggaag
     9421 tttggatgta aaagtcaatg ttactgatag agtcttatat aagaatatac atatgtatca
     9481 tggatataga gaagctgata taaatagtat tatttgtgat aattttgacc cttatagtgg
     9541 attccctgcg tatagaagtt gtaagtgtaa gattgaaaaa atgaatagat aaatggagag
     9601 atataatgaa aagtttattt aaatttaata aagaattatg tacagcatgt ggagcatgtt
     9661 tgcttgcatg tatagaccaa aatgataata atatagacaa tggtgaactt tttagacatg
     9721 tatttacaat agaggaaggt gaaaatatag aatatttttc attagcatgt atacattgta
     9781 atgagccaaa atgtttaggt gtatgtccta aaaattgttt taaaaaagaa gaaggattca
     9841 ttgtattaga caatcaaaac tgtatagggt gtaaactttg tgaaaaagct tgtgaatatg
     9901 gagccttaat ttatggaaat gatggtaagg caaataagtg taatggttgt attgagagat
     9961 ataagtgtgg tatggattca ccttgtgtaa tggtatgtcc tacaggagca ttaaaattta
    10021 ataaataaat taaatataga gaatgactta tacttaggta taagatattt ttacaaaaag
    10081 ctgtattgag tttgttataa tgaaaactca atatagcttt tttatggata tagttggata
    10141 ctataatgtg attcttagta atagtttttt gctattggac aaagactgta aaacatatta
    10201 aacttatgtt gttcaaagtc gaagtataat ataataacta gaaaattggt ttatagtgct
    10261 ataaaagcaa atttagtaag gtataaaatc agaggcaatc ctttactata atatcaatat
    10321 ttgggagttc tgttattgca gagctattaa acaattataa tggtacaagt gattcaacct
    10381 ttgaaaatgt attatataaa aaattaaaat aagattaaaa aggagagaat aaattatgaa
    10441 aaaacttaaa ttaattatta tgtttgcctt ggtatcagca ctgttagtta caggatgttc
    10501 atcaggaaat aataaaaata aagaagaaca aaaagttata agagttgcaa catcaggaac
    10561 atattaccct tttgctttta aagataaaga taaacttaaa gggtttgaag tagatttttg
    10621 ggatgaattt gctaaacgaa ctaattgtaa agttgaatgg gtattaactg attttagtgg
    10681 attatttgga ttattagaag ctgataaagc agatgttgta tctgctcaac ttactgcaac
    10741 acctgaaaga gagaaaaaat atgctttttc agatgcttat aattatagtg gaacaaacat
    10801 tattgttaga gaagatgata ctagtataaa atcaatagat gatttagttg gcaagaaagt
    10861 aggtgtgggt actggagcag tagcaaatga aatattaaaa gaaaaatacc caaatgatga
    10921 aataaaaata gtaaattatt caagtgcgac tcttaaaggg aattatcaag acctagaaat
    10981 gggaagatta gatgcagtag ttgcgcagga tgttgaggct ttaatagcta taaaagaaca
    11041 aaaattaaat cttaaaatga tagaacctcc aattcaattt ggtgcctgtt cttttgcgct
    11101 tcaaaaaaat gaaaaaggtg aaaaatggac aaaagaaatt aacgaagtaa ttgaagagat
    11161 gtataaagat gggactttga ctaaaatatc tgaaaactgg ctaggaaaag acattactaa
    11221 ggagcctatt aatgagtaat tttaattttg aattttgtct aagtatattt ccatttttga
    11281 ttaaagcatt gggaataaca atactaatat ctattgttgc atttttttta tcaatattat
    11341 taggtgtaat acttgccttt ttcacacaga caaaatcaaa agttttacaa tacataacaa
    11401 gagtgtatgt ttcattcttt agaggaacac cacttttaat tcaaatattt ttcttttatt
    11461 ttggatttcc aatgatattt tcttttatga aagattgttc accttattta gcaatagtaa
    11521 tttgtttagg tgtaaattca tctgcatata tggctgaaat tatacgagca tctattgaga
    11581 gtgttgataa aggacaacag gaagcatgtt atgcttttgg gttaagtaaa tatcagtcaa
    11641 tggttaaaat aattctacct caagcagcta catctgcagt acctcctatt gtaagctgta
    11701 cactggacat aattaaaggt tcttctttag gtttaactat aggaatacaa gatttaatgg
    11761 gagtagctca agtagaggct gcttcaagtt ttaaatattt tgagatatat atgataacga
    11821 tattaattta ctgggcagta tctataatat tgagtaatat acaaagcaaa gttgaaaaaa
    11881 gaataagaag agcatattag atttcaatat ttaaaaatgg gatgatatag atatattatt
    11941 acttgtaaat aaatttttaa ttttagaaaa ataaacttag taatctaaat tattgagaaa
    12001 atatagtatc aaaatggact gtataatcaa gttaaaaaat agtttttcta ttgaaaaaat
    12061 aaataaaatt ctattgtaat ttaatatgcg ataaagtttt ataaaaaaca acattaagct
    12121 agggggactt attttatggc ttttaatatg aaatattttt tagaattatt tccaacaata
    12181 atgaaatcgt tcaatgtaac tgtgattttg gcaataagtt cattagtatt ttcattaatt
    12241 ataggtacaa tagtagcgtt atcatcttat tacaaagtga aagtattgaa tcaaatatgt
    12301 aaagtatatg tatctatttt tagaggtaca cctcttatgc cacagttatt ctttttatat
    12361 tttggactag catatatgag tgattttgtt aaaaatatgg acccagtatt tgcaacatct
    12421 atagtactta gtttaaatat gggagcttat atgtctgaaa cgataagggc atctatactt
    12481 tcaattgata caggtcagat agaagcagca tatgcaatgg gattaacaaa tttacaaaca
    12541 atgaaaagga tagtgatacc acaggccgta agagttgcac tgccatcatt attcaataat
    12601 tttatagatt taattaaagg gtcttctgta gcttttgttg ttggagtaaa tgatataatg
    12661 ggtgctgcca aatcacaagg agcgttgagt tttaagtttt ttgaagtgta tggagcagtt
    12721 atggtaattt actggtgtat aataactcct ttaggttggg ggcaaaaaaa attagaaaag
    12781 aaaataagca attattaagt tattaagaaa atacataaaa gtatttttat ataaaaaatg
    12841 gtgtgaggag aagagatatg ataaaaagaa atattataaa atgtttagtg gcagttttat
    12901 cgttaacgtt tgtaattact ggttgttcaa aaaaagagga agtaaagaat gaaaaagtta
    12961 taactgtagc ttcatctaat tcagctgacc catattctta tgttgataat ggtgagcata
    13021 agggttttga agttgacatg tggaaagaga ttggtaaaag aagtggatat aagataaaaa
    13081 tggaaccaac aggttttagt tctatatttg gtatgttaga ttctggtaaa gttgatgtgg
    13141 cagccaactt ctttggaatg tctaaagaaa gattagaaaa atacgatgct tctatacctt
    13201 atggttctga ttctgtgtgt atagctgtaa aagatggaaa taacgaaatt aataagcttg
    13261 aagatttaaa gggaaaagtt gtagcagttt cagaaggttc tcaaggtcaa caggttgcaa
    13321 ctagtgttaa taaagataat ttgtttcaag aaaaggttta cggtgatgga actagtggtc
    13381 ttcaagattt agatttggga agagttagtg catggattga tgcagagctt actattgtgg
    13441 gagacgctaa aaaagctaat atgaaagtaa gagtattaga taaaaaatta tcagctacta
    13501 atatagcata cttctttaag aaaaacgatg ataaatctaa aacgataaaa gaagatgtaa
    13561 acaaagcaat agaagaaatg cttgcagatg gaacagtgaa aaaaatatct gaaaaatggt
    13621 ttggaatgga tgtaagtgct gatatacaaa aataaatact ttaaaattaa aatgtaaaac
    13681 tgtgataact atagataagt atactaaatt tatctatagt tatctgtgta ttacaatgta
    13741 tttagattag tctttataaa tcaaaatgag ttatggaggt attgcaaatg attgaaacta
    13801 aaataaaatc cattgcacta aaaaatagag aaaaaattat aaaaataaga cgacagatac
    13861 acagtaatcc agagttagca tttaaagaat ataaaacatc taaacttata aaagaagagc
    13921 taaataaact taatatagaa tacataaata ttgctggtac aggagtatta gctactataa
    13981 aaggaaaaaa taatggtgga aaaactatat tactcagagc ggatatggat gctcttccaa
    14041 tcaaagagga aaatgattta gaatttaaat caataaatga taatatgcat gcttgtgggc
    14101 atgatgcaca tgtttcatgg ttgttaggaa cagcaatgat tttaaatgac ataaaagaag
    14161 aattgaatgg aaatgtaaaa ttactatttc aacctggcga agaaaaaggt ggttctgata
    14221 ttgtaattaa agaaaatgta cttgaaggtg tggatgcatt agcgactggt cattgttggc
    14281 caactattga gtcaggaaaa attggaatcg ctagaaattg tgctatggca gcgactaata
    14341 cttttgaaat aacaataatt ggcaagggtg ggcatggagc agagcctcat aattgtatag
    14401 acccaattgc agttggaaat gcagtatatt catccattca acagatagtt tcaagaaaaa
    14461 ttgacccagt tgtacctgta gtagtgtctg tttgttcttt taattctggt gtttctaaaa
    14521 atataatacc agatgtatgt acacttcaag ggactattag agcgataagc aaggaacaag
    14581 taattgaagt aagtaaaatt ctagaatata tagtaaaaaa tgtatgtaaa gcacatggag
    14641 cagattgcaa atttgaaaag agtacaggag gagatgctgt tataaatgac aaaaacatga
    14701 tagagatagg aagagaaagt gcttgcaaaa tacttggagc tgaaaatgtt gaaataattg
    14761 attttcctgc aatgacaggt gaggattttg ctatttatat gaaagaaaaa cctggtttat
    14821 ttatgtatat aggtgtagga gataaagaaa aaaatataaa ttacagattg catagtaaca
    14881 agtttaatat agatgaaaaa tgtcttagta tagcaccttc attattttca caacttacag
    14941 tagattattt atgtcaacta tagagtacat tcataaaaat atatttagcc tatttttaaa
    15001 tttaatgcta gtatattaat tttgatgtag aacatattat ttattatatt tatttaaaaa
    15061 ggtggataac aatgataaaa gtagaaaatt tacataaaag ttttaaaggg acagaagttc
    15121 ttaaaggtat aaatttagag ataagtcaaa gtgaagtagt agctatactt ggatcatctg
    15181 gaacaggtaa atctacgtta cttagatgtt taaattattt agttgagcct acaaaaggaa
    15241 agataatgat tggtgatgta aaagtagatg tagaaaaagc aacaaaaaaa gatataacca
    15301 atttaagaaa acatacatct atggtgtttc aaaattataa cttatttaaa aataaaacag
    15361 cattagaaaa tgtaatggag gcattgatag tagttcataa aaagagtaag aaagaagcta
    15421 gagaaatatc tttaaaatta atagataaag taggtatgtt ggataggaaa gatttttatc
    15481 catcaaagtt gtctggggga cagcaacaaa ggataggtat agcgagagcg atggcagtaa
    15541 atccaaatgt aatattattt gatgagccta catctgcact tgacccagaa cttgttggag
    15601 aagttttaag cgttataaaa tctcttgcaa aagaaggtat aacgatgctt attgtaactc
    15661 acgaaataaa ttttgcaaaa gaagttgctg ataaaattat atttatggat aatggtgtaa
    15721 tagctgaaga aggaactcct gatgaaatat ttaataatcc taaaaatgaa agaacagcaa
    15781 aatttttaaa tatcattagg aaagaagaag tatttagtta aaagtgtata aattaagcat
    15841 tagaagatat gtaagatacc cccattaaat ttataagtta gataataaat ttaatgggag
    15901 tatattttta ttattagatt tattatttaa tttaaaatta gaaatgtaac tatttgaaaa
    15961 ttctttttaa aagtatatca aaatatcaaa tacataaaaa aataatattt gacaaagtat
    16021 catatgtgtt t
//
LOCUS       DAJMZY010000094        15915 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.095, whole genome shotgun sequence.
ACCESSION   DAJMZY010000094 DAJMZY010000000
VERSION     DAJMZY010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15915)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15915)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15915
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.095"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            <1..1030
                     /locus_tag="OE968_002892"
     CDS             <1..1030
                     /locus_tag="OE968_002892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HCP7220153.1"
                     /translation="MKYIEEEDITKRLKTIFEELDLFNNNQEEKYKLVLSCGIYFILP
                     EDRDINSIIDRANIPHKMAKGGHKSSYAFYDNKIHDQEIKEKEMENTMFSSLENKEFI
                     IYLQPKIELNTGEIQGSEALVRWKRPDKGLIPPNEFIPFFERNGFVINLDLYVLEEVC
                     IYLRKWIDAGINPVTVSVNVSRIHLYCNNFIETYKNIIDKYNIPAKYIELELTESIIF
                     DNFDILIDIMNNLKKIGFLISMDDFGSGYSSLNMLKEIPMDILKLDQKFIMETYNSKR
                     SKIIVTKVIEMAKELGMKVISEGVETEEQFKLLKEVKCDMAQGYLFGKPMPIEEFEHL
                     IVSNLVRG"
     gene            1206..1574
                     /locus_tag="OE968_002893"
     CDS             1206..1574
                     /locus_tag="OE968_002893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCP7220154.1"
                     /translation="MEWELDNNKPIYIQLVEHLKLKIISGEIKIGSKLETVRALAEDA
                     EVNPNTMQKALTELERQGLVYSQRTKGRFVTDDKEKIKAMKEEIANVEINTLKVTLEK
                     LGYDRDEMLKLITENLKGEL"
     gene            1576..2301
                     /locus_tag="OE968_002894"
     CDS             1576..2301
                     /locus_tag="OE968_002894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCP7220155.1"
                     /translation="MDKNISNVSQDGIVEFKGVNKSYGTKNVLKNIDLNIPKGKIVGL
                     LGPNGSGKSTMIKLMNGLLQPDNGEIMINGMKPSIDTKKIVSYLPERTYLNDWMKVSD
                     LLKFFYDFYSDFDVRRANEMIKSLDIDVNEKLKTMSKGTKEKVQLILVMSRNASIYIL
                     DEPIGGVDPAARSYILKTILKNYSEDSTLLIATHLISEIENICDEIIFISKGEIVLQG
                     DVEAIREEKGKSIDALFREEFKC"
     gene            2295..3059
                     /locus_tag="OE968_002895"
     CDS             2295..3059
                     /locus_tag="OE968_002895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCP7220156.1"
                     /translation="MLGKLLKYELKASGRIFIPLYIAILIVAVFNGIFMNTNILQVQG
                     IGILVLTSLFMALGVLTIVVTIQRFRKNLLGDEGYLMFTLPVSTSSLILSKCITALIY
                     AVLSFIVAVFTFGVLMLFGTSGILLPEILDLFNTSFKWISENFLDILLLVVVMFISYS
                     SFILLLYTSISMGQLPKFNKHRNIVAFASFIAINIVISIVGDAVGSILPNEDTNMVYH
                     LYQSPSFMLAILGSLVVAIALFFATKFILDKKLNLE"
     gene            3281..4531
                     /locus_tag="OE968_002896"
     CDS             3281..4531
                     /locus_tag="OE968_002896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCP7220157.1"
                     /translation="MKSYTKAKWSVWGIITFSFVLVLFLRMSTAVVSDNLANELGFNS
                     IQISNIASFCLYAYAFMQIPAGILIDKYGARKISSLGIIMASLGSILFGLIQSIELAY
                     ISRVIVGAGTSVILLCILKIQGRWFNKSEFASATAKFSFVGNLGGVLATFPLVFLSEL
                     VGWRNSFLLIGIIGVVIGCFMYIIVRDTPKEYGFNIDTEPYEKSEKVNIVDGIKSVIK
                     NKSTWYNSMIMFSFVGLTSAFISLWGVRYIMDVYGVSKSFSAFIVSFFTYGFIFGSII
                     MDFVFAKIRSSKFNIIKFGAMIDLFIWIVIVVVYQVKPPIIVLPISFFIMGCIVMSHL
                     QVFNDAKYKNKEIYSGLATSVINTFEFIGSGIINLIIAISLQVNSYNIVDGYKKGFVV
                     FIVLSIITIVSSHIGVKNDDFKAI"
     gene            4724..5608
                     /locus_tag="OE968_002897"
     CDS             4724..5608
                     /locus_tag="OE968_002897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HCP7220158.1"
                     /translation="MDTTKIDDISKLDLNNLDINKMDMGGIMESLLEWATTSGVKLII
                     GILILSIGFKIIKKFVNHVMLLLSKRDIDLTLRRFLKSLLLSVLKVAVIIIVLEYWGM
                     SLSSFAAVIASAGVAIGLALQGSLSNFAGGFIILLIRPFKVGDYVEAAGHGGTVEQIG
                     LFYTQLVTPDNKQILIPNGSVSNDSLINYSAKNTRRVDLTFSVGYEDDILHVRRVLKD
                     IVNNHKLIINEPEPFIGVVEHGDNAIKFATRVWCKTEDYWTIYLDLLEEVKVRFDEEG
                     ITIPYPKMDLTVKELNKI"
     gene            5967..6584
                     /locus_tag="OE968_002898"
     CDS             5967..6584
                     /locus_tag="OE968_002898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HCP7220159.1"
                     /translation="MCKKMYLLVVGILIAGLLTACNGSPTKDSEQAQDNTKKEANVSN
                     NALKDEKNNENLMEQDFKVPYTDAINIFKDKYKDADIVDLSLERDLNKFVYTVEGVDD
                     NNEYKMKIDANTKDVLEDKTEKLDSEDLNGVARKEKLDFNDIMTPQQAMEIALKEQNG
                     MVKEWSLDKDLDVTFYKIRIDKDKNEYDIKVDSKKGTVLKVEKED"
     gene            6692..9223
                     /locus_tag="OE968_002899"
     CDS             6692..9223
                     /locus_tag="OE968_002899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HCP7220160.1"
                     /translation="MSLKSLKIKENLYWVGSLDPDLRVFDIIMYTPYGTTYNSYVLKG
                     TEKTVLFETVKDKHFDNYIERLNDLNIDFEKIDYIVVSHTEPDHAGSVEKLLDLAKNA
                     KVVASETAIKYLKEIVNKDFEYVAVTDGDTLSIGDKTLEFFSVPMLHWPDTIYTYIKE
                     DKTLVTCDSFGSHYSNDKIVNTLDEDEEKDYLDALRYYYDCIMGPFKPSMVTAIEKIK
                     DLDIDTVCPGHGPVLTENPRKIIDLYYNWSVNEQIKLEKEVTICYVSAHGYTKIMAEA
                     IKAYIEKNSNYKVNLFDVIEHKQEDILAKIAVSQGVLFGTPTILGDALKPIWDILISL
                     NPVLHGGKVASVFGSYGWSGEGIENAMERISQLRMTAVKPFAVNFKPSNEEIDKLHSY
                     TGKFLDKLNSTFGSKKKTKKFKCVICNEVFEGDSAPSVCPVCGAKEDQFIEVEEDEVT
                     FRKDTDEYFVIVGNGAAGFYAADAIRKRNKTCKITMISNEDELTYYRPALSDGINEEL
                     GSDFYMEDKDWYDKNNIVVILGTNVDKLDEVNKTIIVNDGAIKFDKLVIATGSRNFIP
                     PIKGHDLENVFTLRNIKDLYSVKEALEKSKKVVVIGGGLLGLEAAWEFRLKGLEVVVV
                     EAMDSILSKQLDKEGSKILEQCVRDTGIDVRLGVAVDGIEGDGKAQKVVFKDGDSVDC
                     DMVVFSIGVRANTQMVQDTSVKIDRGIVVDKTLQTNVKDIYACGDVAQVGNISLAIWP
                     SSVEMGKIAGANASGDNLTFESEVYPVSLDAMNVKVFSIGNIQNFDKEISSKDEGQRI
                     YKKLFMKDGSLVGAILINDLSCTVKLIRLISEKGDFEDIMKADIL"
     gene            9657..10358
                     /locus_tag="OE968_002900"
     CDS             9657..10358
                     /locus_tag="OE968_002900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanG-Cd-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HCP7220161.1"
                     /translation="MNENILIVDDEKEIADLIEVYLKNEGFTVYKFYTGKEALECIES
                     KNLDMAILDIMLPDIDGFHICQKIREKYYYPIIMLTAKIEDIDKIMGLTIGADDYITK
                     PFNPLEVVARVKTQLRRYMRYNNSYEQQSIIVNEYDIKGLIINKETHKCSLFGKEVAL
                     TPIEFSILWYLCEHQGKVVPSEELFEAVWGEKYLDNNNTVMAHIGRLREKIHEPSKNP
                     KFIKTVWGVGYTIEK"
     gene            10408..11490
                     /locus_tag="OE968_002901"
     CDS             10408..11490
                     /locus_tag="OE968_002901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HCP7220162.1"
                     /translation="MRTALMAFIAIIFIWILYSFILYGKFSIWIVSFFENAFRMEYKA
                     ALNLYQQIFRNSMELFMILAMVIVFFIIFRVYLNWFTKYFSEINQGIDSLIKEDVGEV
                     ALSPELLAIEKKINSIKHILEQRKFETQMAEQRKNELIVYLAHDLKTPLTSVIGYLTL
                     LRDESQISEELRKKYLSISLDKAERLEDLINEFFEITRFNLSNISLEYSTVSLTRMLE
                     QLTYEFKPTLMSKNLKYTLNVTPNMMIRCDVNKMQRVFDNLLRNAVYYSFEDTTIEIT
                     AVQEDDYIKLKFINHSNTIPEEKLERIFEQFYRLDTSRNSNSGRAGLGLAIAKEIVEL
                     HNGTITAHSENNIITFKVIIPIVGNL"
     gene            11751..12851
                     /gene="vanG"
                     /locus_tag="OE968_002902"
     CDS             11751..12851
                     /gene="vanG"
                     /locus_tag="OE968_002902"
                     /EC_number="6.3.2.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-serine ligase VanG"
                     /protein_id="HCP7220163.1"
                     /translation="MNNKKIAVIFGGNSTEYDVSLQSAFAVLENLNTEKYDIIPIGIT
                     REGNWYHYIGDYNNIQNNTWFERDTDIIPVIVSQNRVKNGIIEFLIPDAVSQNHIPNS
                     AIESCENDIKYTKLDFVFPVLHGKNGEDGTVQGLFELAGIQVIGCGTLSSALCMDKDK
                     SHKLVHSEGIKVPKSILLKYSDKFNVAELSKDLTYPLFIKPVRAGSSFGISKIYKKEE
                     LQVAVDLAFEHDNEVIIEENIDGFEVGCAVLGNNDLLVGRVDEIELSKGFFDYTEKYT
                     LKSSKIHMPARIDLDCEKRIQETAKIIYRTLGCSGFARVDMFLTPSGEIIFNEVNTIP
                     GFTSHSRYPNMMKGIGLSFEEILDKIIEVYIK"
     gene            12848..13654
                     /locus_tag="OE968_002903"
     CDS             12848..13654
                     /locus_tag="OE968_002903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HCP7220164.1"
                     /translation="MMNNILLDKNKEDKMTNTILLTKDKVYDGNLILVNAFLPVKTSE
                     DIDLIPVDTRFPSILMKREATNILQNILKSICGINEIVPVSGYRTAEEQQDIYSSSLR
                     DNGKDFTKKFVALPNHSEHQTGLAIDLGLKKEVIDFICPEFPYNGICNEFRKAALHYG
                     FIERYQCKKEEITGISQEPWHFRYVGYPHSEIINKMNLALEEYIEYIKRFSYTNCLKI
                     EDKEKIIEIFYVPIHTKEEVRISIPEQCVYQISGNNKDGFIVTFWRNRKD"
     gene            13672..15810
                     /gene="vanT"
                     /locus_tag="OE968_002904"
     CDS             13672..15810
                     /gene="vanT"
                     /locus_tag="OE968_002904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine racemase VanT catalytic subunit"
                     /protein_id="HCP7220165.1"
                     /translation="MIRNKSYAGLDYFRIIAALLIIAIHTSPLLSYSKMADFVLTSII
                     ARIAVPFFFMLSGFFLISTYNYNCNKLKSFLKNVLFIYGIAIVIYIPLNIYTGYFSMN
                     NLVPNIIKDIVFDGTLYHLWYLPASIIGASIAYFLVKKLGLKYSLVITIVIYVIGMFG
                     DSYYGFLEKIPLLKNLYGYIFEVSDYTRNGIFFAPVFFILGGIISNKSNYMSTKNSLI
                     GFLISFLLMLCEGMFLHKLGVQRHDSMYIMLLPCMYFLFTALTFLKGSRARLLRTSSL
                     IIYIIHPMMIVVIRMFSKIFGIQTVLVDNSLIHYIVVSIASFIASIIIILILKPLKKD
                     LKGEHKVNTNRAWIEIDLNNLEHNVKMIQKAMPEDCELMAVVKANAYGHSAFEVATCA
                     NQIGVKAFAVATIDEGIDLRRYGILGEILILGYTNPIRAKELHKYNLTQSVIDLNHAI
                     SLNKQKYNIKSHIKIDTGMHRLGFDVNDVRSILKAFKLKYLDICGIFTHLCVSDSLKD
                     EDVDFTNKQIECFYKLIDFLLKKGIKIPKVHIQSSYGFFNYPNLKCNYVRIGIALYGI
                     LSFPNDTTKLQLDLRPVLSLKSQVILIRKIQKDDSFGYGRVFIASRDSVIAILSIGYA
                     DGIPRNLSCGKSYVIINGCRAAIVGRICMDQLAVDITDIPNVEVGNTAIIIGRDNLSE
                     LSVSEVANNSCSISNELLSRVGRRLNVIKK"
BASE COUNT         6042 a         1602 c         2854 g         5417 t
ORIGIN      
        1 tatgaaatat atagaagaag aagatataac aaagaggtta aaaactatat ttgaagaatt
       61 agacttgttt aataataatc aagaagaaaa atataagtta gttttaagtt gtggaatcta
      121 ttttatactt ccagaagata gagatatcaa ctcaatcata gatagggcta atatacctca
      181 taaaatggca aagggaggac ataaaagttc atatgcattt tatgataata agattcatga
      241 ccaagagata aaagaaaaag agatggaaaa tacaatgttt tcaagtctag aaaataaaga
      301 atttattata tacttacaac ctaagataga acttaataca ggagagatac aaggttcaga
      361 agcacttgtt aggtggaaac gtcctgataa agggctaata cctccaaatg aatttatccc
      421 attttttgaa agaaacggtt ttgttataaa tttagattta tatgtgcttg aagaagtatg
      481 tatatacctt agaaaatgga ttgatgcagg aataaatcca gttactgttt cagttaatgt
      541 ttcaaggata catttatatt gcaataattt tatagaaaca tacaaaaata taattgataa
      601 atacaatata cctgcaaagt atatagaact tgaattaacg gagagtatca tatttgataa
      661 ttttgatatt ttaattgata taatgaataa tttaaaaaaa ataggatttt taatatctat
      721 ggatgatttt ggctcagggt actcatcatt aaatatgtta aaagaaattc ctatggatat
      781 cttaaaactt gaccaaaaat ttattatgga aacttataat agtaaaagaa gcaaaataat
      841 tgttactaaa gtaatagaaa tggcaaaaga gttgggtatg aaagtcatat cagaaggagt
      901 tgagacagaa gaacagttta aacttttaaa agaagtaaag tgtgatatgg cacaaggata
      961 tttgtttgga aagccaatgc caattgaaga atttgaacat ttaattgtat ctaacttggt
     1021 aagagggtaa ttaatctgta atataaagaa tttaataaat tgtgttaaaa atggactcta
     1081 atgtagtgtt catttttttt gtaaaatttt ttatactttt actaaaaagt aattgacata
     1141 tactttgtat tattatatta ttgtattaac aacttaatac aataatataa taaggaggca
     1201 tgaacatgga atgggaactt gataataaca aacctatata tatacaatta gtagaacatt
     1261 taaagttaaa aataatttca ggggaaatta aaataggatc taaattagaa acagtgagag
     1321 cactagcaga agatgcggaa gttaatccaa atacaatgca aaaggctcta acagaacttg
     1381 aaagacaagg tttagtttat agtcagagaa ctaaaggaag atttgtaaca gatgataagg
     1441 aaaaaataaa agctatgaaa gaggaaatag ctaatgtgga gataaataca ttaaaagtaa
     1501 ccttagaaaa gcttggatat gatagagatg aaatgctaaa acttattaca gaaaatctga
     1561 aaggagaatt ataaaatgga taaaaatata agcaatgttt ctcaagatgg aatagttgaa
     1621 tttaaaggtg taaacaagag ttatggaact aagaatgttt taaaaaatat tgatttaaat
     1681 ataccaaagg gaaaaatagt cgggctgtta ggacctaatg gaagtggcaa aagtacaatg
     1741 attaagctaa tgaatggatt attacagcct gataatggtg aaattatgat aaatggaatg
     1801 aaaccatcca tagatactaa aaaaatagtt tcatatttac cagaaagaac ttatttaaat
     1861 gattggatga aggtatcaga tttacttaag tttttctatg atttttatag tgattttgat
     1921 gttagaagag caaatgagat gattaaaagc ttagatattg atgtaaatga aaagctaaag
     1981 acaatgtcta aaggaactaa agaaaaagtt caacttattt tagtaatgtc aagaaatgcg
     2041 agcatatata tattggatga acctataggt ggtgttgacc cagctgcaag gtcatatata
     2101 cttaagacta tattaaaaaa ttattctgaa gatagtactt tactgattgc tacccattta
     2161 ataagtgaaa tagaaaacat atgtgatgag ataatattca tatcaaaagg agaaatagtg
     2221 ttacaaggag acgttgaagc aataagagaa gaaaaaggaa aatctataga tgcattattt
     2281 agggaggaat ttaaatgtta ggtaaattat taaaatatga gttaaaagca agtggaagaa
     2341 tatttatacc gttatatata gccatattga tagtagctgt atttaacgga atatttatga
     2401 atacaaatat acttcaggta cagggaatag gaatactagt attaacaagt ctttttatgg
     2461 cattaggagt tttaactatt gtagttacaa ttcaaaggtt tagaaaaaat cttttggggg
     2521 atgaaggtta tttaatgttt actcttcctg ttagcactag ttcacttata ttatctaaat
     2581 gtataacagc acttatatac gctgtactta gttttatagt tgcagtattc acttttggag
     2641 ttcttatgct ttttggtact tctggaattt tactacctga aattttagat ttgtttaaca
     2701 ctagttttaa atggatttct gaaaactttt tagatatttt attattagta gtagtaatgt
     2761 ttatttcata ttcatcattt attttgttat tatatacatc aatctcaatg ggacaattac
     2821 caaaattcaa taaacataga aacatagtgg catttgcttc ttttatagct ataaatatag
     2881 taatatcaat tgttggagat gcagttggaa gcatcttacc aaatgaagat acaaatatgg
     2941 tatatcatct ttatcagagt cctagtttta tgcttgcaat acttggtagt cttgtagttg
     3001 caatagcgtt atttttcgct acaaaattta tattagataa aaaattaaat ttagaataaa
     3061 tgtttttata tggagccatc ttttgagtaa tgttaaaaga tggctcttat tatttatgta
     3121 gttaattcat gtatataata tgaatagtgt tttatttcta gttaaatata tacatatgtt
     3181 gtataatgat attgcgtgta aaaatttgta agaataacta tacactttat ataagttata
     3241 tcaagaaaat ttaaaaatat atggatttga gggagaagat atgaaaagtt atacaaaggc
     3301 taagtggagt gtttggggta taattacatt ttcatttgtt ttagtattat ttttaaggat
     3361 gtcaactgct gttgtttcag acaatttagc aaatgagtta ggttttaatt ctatacaaat
     3421 ttcaaatata gcatcctttt gcctatatgc atatgcattt atgcaaatac ctgcaggaat
     3481 tttgattgat aaatatggag caagaaaaat tagcagtctt ggaataataa tggcaagttt
     3541 agggtcaatt ttatttggtt tgattcaaag tatagaatta gcatatattt ctcgtgtaat
     3601 tgtaggggca ggaacatcag taatattact ttgtatttta aaaattcaag ggagatggtt
     3661 taataagtca gaatttgctt ctgcaacagc taaattttca tttgtaggaa atttaggtgg
     3721 agttcttgct acttttccac ttgtgttttt gtctgaactt gttggttgga gaaattcatt
     3781 tttattaatc ggtataattg gtgttgtaat tggatgtttt atgtatatta ttgttagaga
     3841 tacaccaaaa gagtatggat tcaatataga tactgaaccc tatgaaaagt cagagaaggt
     3901 taatattgtt gatggtatta agtctgttat aaagaacaaa tcaacatggt ataattcaat
     3961 gataatgttc tcttttgtgg gtcttacaag tgcatttata agcttgtggg gagtaagata
     4021 cataatggac gtttatggtg tgagtaagag tttttctgcg tttatagtat cattttttac
     4081 atatggattt atatttggtt caataattat ggattttgta tttgctaaaa taaggtctag
     4141 caaatttaat ataataaaat ttggggcaat gatagatttg tttatatgga ttgtaattgt
     4201 agttgtatac caggtaaaac caccaattat agttttacca atatcattct ttattatggg
     4261 atgtatagtt atgtcacatc tacaggtttt taatgatgcc aagtataaaa ataaagaaat
     4321 ttattctgga ctggcaacta gtgttattaa tacttttgaa tttataggaa gtggaattat
     4381 taatttgatt atagctatct ctttacaagt aaattcatat aatatagttg atggatataa
     4441 aaaaggtttt gtagtattta tagtactaag tattataact atagtatcat ctcatatagg
     4501 ggtaaaaaat gatgatttta aggctatata gtgttttatt aatagtttaa tttagtatta
     4561 tattttgcat atatatataa caaatagttt gcattttcct aagatgtata attggaatat
     4621 aaatcttgtt tactatgtac aaatggtatt gtattatatt aaatagaaaa taagaacttt
     4681 aaactataat attggttcta aaatataagg taaggagttt tttatggata cgacgaaaat
     4741 agatgatata agcaagttag atttaaataa tttagatatt aataagatgg atatgggagg
     4801 tataatggaa agtctattag aatgggctac tacaagcgga gtaaaactta taataggcat
     4861 acttatactt tctattggat ttaaaataat aaaaaaattt gtaaaccatg ttatgttatt
     4921 acttagtaaa agagatattg atttaacttt aagaaggttt ttgaagtctc ttcttttgag
     4981 tgtacttaaa gttgccgtta taatcattgt tctggaatat tggggaatga gtttgtccag
     5041 ttttgctgct gtgatagcat cagcaggggt agcaataggt ttggctttac aaggtagtct
     5101 atcaaatttt gctggaggat ttattatact attgattaga ccttttaaag taggagatta
     5161 cgtagaagca gcaggccatg gaggaacggt tgaacaaata ggactttttt atacacaatt
     5221 ggttactcca gataataaac agatacttat acctaatggt tctgtatcaa atgatagtct
     5281 aataaactat tcagcaaaga atactagacg agttgatttg acttttagtg tagggtatga
     5341 agatgatata ctacatgtta gaagagtact taaagatatt gttaataatc ataaattaat
     5401 aataaatgaa ccagaaccat ttataggagt agtagaacat ggagataatg ctattaaatt
     5461 tgcaactaga gtttggtgca agacagaaga ttattggaca atttatcttg atttactaga
     5521 agaggttaaa gttaggtttg acgaagaagg aattacgatt ccatatccta aaatggattt
     5581 aacggtaaaa gaattaaata aaatttaatt tttttatgta gtgtttaaat ttaagaatat
     5641 tatatagata tatttataag atttgtgaaa aattaataag tcctgttatt ttgtaagtga
     5701 aaatataaaa aatgggagtg tctcaaaatg aactttttag ttcatgaggc actctttttg
     5761 tatgaaatca aatatatttt tattatttca acaataaaaa agaggtctgt ttctattttg
     5821 agacaatatt atttttatgt agatttaatc ttaatgagta taaagtttta aaactactaa
     5881 aataggagga attttaatat aaaagggtaa ataaagggtt tagagggcat aatatagaat
     5941 aaattaatta tttaaggagg gtttttatgt gcaaaaaaat gtatttatta gtggtaggta
     6001 tacttatagc aggtttatta actgcatgta atgggagtcc aactaaggat tcagaacaag
     6061 cacaagataa tacaaaaaag gaggcaaatg tatcaaataa cgctttaaaa gatgaaaaaa
     6121 ataatgaaaa tttaatggaa caagatttta aagtgccata cacagatgca ataaacatat
     6181 ttaaagacaa atacaaagat gctgatatag tagatttaag tcttgagaga gatttaaata
     6241 aatttgttta tactgtggaa ggtgtagatg ataataatga atataagatg aaaattgatg
     6301 ctaatacaaa agatgtatta gaagataaaa cagaaaagtt ggattcagaa gatttaaatg
     6361 gagtcgctag aaaagaaaaa ttagatttta atgacataat gacacctcaa caagctatgg
     6421 aaattgcatt aaaagaacaa aatggaatgg ttaaagagtg gagtttagat aaagatttag
     6481 atgttacttt ttataaaata agaatagata aagataaaaa tgaatatgac ataaaagtag
     6541 attctaaaaa gggaactgta ttgaaggtag aaaaagaaga ttagaagatt taaactatct
     6601 ttaaaataat ttcttttttg aataaaattt gtttaaaata taacaagtag ggtataaaga
     6661 gactaaataa ctattttagg aggagtacgg tatgtcattg aaatcgctaa aaataaaaga
     6721 aaatttatat tgggtaggtt cgcttgaccc tgatttaaga gtatttgaca taattatgta
     6781 tacaccttat ggaactactt ataattcata tgtattaaaa ggaacagaaa aaacagtttt
     6841 atttgagaca gttaaagata agcattttga caattatatt gaaagattaa atgatttaaa
     6901 tatagatttt gaaaaaatag actatattgt tgtaagtcat actgaaccag accatgcagg
     6961 aagcgttgaa aagcttttgg atttagctaa aaatgcaaaa gtagtagctt cagaaacagc
     7021 aattaaatat cttaaggaaa tcgtaaacaa agactttgaa tatgttgcag ttacagatgg
     7081 agatacatta tcaattgggg acaaaacttt agaatttttc tctgtaccta tgcttcattg
     7141 gccagatacc atatacacat atataaaaga ggataaaact cttgtaacat gtgattcatt
     7201 tggtagtcac tatagtaatg ataagatagt aaatacactt gatgaagatg aagaaaagga
     7261 ttacttggat gctttgagat actattatga ttgtataatg ggaccattta aaccatctat
     7321 ggtaactgcc atagaaaaga taaaagattt agatatagat actgtatgtc caggtcatgg
     7381 tccagtatta actgaaaatc ctagaaaaat tatagacctt tattacaact ggagtgtaaa
     7441 tgaacaaata aagttagaaa aagaagttac aatttgttat gtttctgcac atggatatac
     7501 aaagattatg gcagaagcta taaaagcata tattgaaaaa aatagcaact ataaagtaaa
     7561 tttatttgat gtaatagagc ataagcaaga agatattttg gcaaaaatag cagtatcaca
     7621 aggtgtatta tttggaacac caacaatatt aggagatgcg ttaaagccta tatgggatat
     7681 attaatatcg ttaaacccag ttcttcatgg tggaaaagtt gcttcagtat ttggttcata
     7741 tggatggagt ggagaaggta tagaaaatgc tatggagaga ataagtcagc ttagaatgac
     7801 agcagtaaaa ccttttgctg ttaactttaa accatcaaat gaagagattg ataaattaca
     7861 ttcttataca ggtaaattcc tagataagtt aaattctact tttggaagta aaaagaaaac
     7921 taagaaattt aaatgtgtaa tttgtaatga agtttttgaa ggtgatagtg ctcctagtgt
     7981 atgccctgta tgtggagcta aggaagacca atttatagaa gttgaagaag atgaagttac
     8041 ttttagaaaa gatactgatg aatatttcgt aatagtagga aatggagcag ctggttttta
     8101 tgcagcagat gctataagaa aaagaaataa aacttgtaag ataactatga tttctaatga
     8161 agatgagttg acttactata gacctgcact ttctgatggt ataaatgaag aacttggttc
     8221 agatttctac atggaagata aagattggta tgataaaaat aatatagtag taatattagg
     8281 aacgaatgta gataaattag atgaagtgaa taaaactatt atagtgaatg atggagctat
     8341 taaatttgat aagcttgtaa tagctacagg aagtagaaac tttataccac caattaaggg
     8401 tcatgattta gaaaatgtgt ttactcttag aaatataaaa gatttatata gtgtaaaaga
     8461 agcactagaa aaatctaaga aagttgtagt gattggtggc ggtttattgg gacttgaagc
     8521 tgcatgggaa tttagactaa aaggattaga agtagtagta gttgaagcca tggatagcat
     8581 actatcaaaa caacttgata aagaaggcag taaaatatta gaacaatgtg taagagatac
     8641 aggaatagat gtaagattgg gtgtagcagt tgatggtatt gaaggtgatg gaaaagctca
     8701 aaaagttgta tttaaagatg gagatagtgt tgactgtgat atggtagtat tttcaattgg
     8761 tgtaagagca aacactcaaa tggttcagga tacatctgta aaaattgaca gaggtattgt
     8821 tgtagataag acattacaga caaatgttaa agatatatat gcttgtggag atgttgcaca
     8881 agtgggaaat attagtttag caatatggcc atcttcagta gaaatgggaa aaatagcagg
     8941 ggcaaatgca agtggagata atttgacatt tgaaagtgaa gtatatccag tttcattaga
     9001 tgcaatgaat gtaaaagtat ttagtattgg taatatacaa aattttgata aagaaatttc
     9061 atcaaaagat gaaggtcaaa gaatatataa aaaattattt atgaaagatg gttcattagt
     9121 tggagctata cttataaatg atttaagctg tactgttaaa ttgataagat taatatctga
     9181 aaaaggtgat tttgaggata ttatgaaggc tgatatacta taatttaaat acattaaaat
     9241 aaaaaggagt tgtcttaaaa ttgatttttt tctaatcaaa ttttaaattc aactcctttt
     9301 ttgaattttt atataaaata acatggaaat tttagtaatg tctgtggtta catacatagg
     9361 tttaattgtt ttttatatgg attgtctctg gtataataaa ttgaattgtg tttgactgat
     9421 agatattttt attgaaagtt aatacctgtt atgcgataat aaggacgtgt taggggagtt
     9481 tttataataa caattaatct cagtttttgt gttccaatag tagcatcaac acattctgat
     9541 gtagtagttc ttttcttata aaaattagtt acaaatatgc ttgtaattat ttgatatgta
     9601 aatttaccaa tattataaat gatgacctcg ataataagga gagtgaaaaa taatctatga
     9661 acgaaaatat tttgattgtg gatgatgaaa aagaaatagc agatttaatt gaagtatatt
     9721 taaaaaatga aggttttaca gtatacaagt tttatacagg taaggaagct ctagaatgta
     9781 ttgaatctaa aaatttggat atggctattt tagatattat gcttcctgat attgatggat
     9841 ttcatatttg ccagaaaatt cgagaaaaat actattatcc tatcattatg ttaacagcta
     9901 aaattgaaga tatagacaag ataatgggtt taaccatagg tgctgatgat tatataacaa
     9961 agccatttaa ccctttggaa gttgttgcaa gagtaaagac acaattaaga agatatatgc
    10021 gatataataa ttcttatgaa caacagtcga taattgttaa tgagtatgat attaaaggat
    10081 tgattatcaa taaagaaaca cataaatgta gtttatttgg gaaagaagta gcattaacac
    10141 cgattgaatt ttctattctt tggtatttat gtgaacatca aggaaaagtg gttccttctg
    10201 aagaattgtt tgaagctgta tggggagaaa aatatcttga taataataac acagttatgg
    10261 ctcatatagg gcgattacgt gaaaaaattc atgaaccttc taaaaacccg aaatttataa
    10321 aaactgtatg gggagtaggt tatacaattg aaaagtaaaa atattaaagt caatcctgac
    10381 tttactcaag tgagaaataa aatttttatg agaacagctt taatggcatt tatagccatt
    10441 attttcatat ggattttata ttcttttata ttgtatggta agttttctat ctggatagta
    10501 tcattctttg aaaatgcttt tcgtatggaa tataaagctg cattgaattt atatcagcag
    10561 attttccgta atagtatgga gctcttcatg atactagcta tggtgattgt gttttttata
    10621 atattccgtg tttatttaaa ttggtttaca aaatatttta gtgaaataaa tcaaggtatt
    10681 gactctctta tcaaagaaga tgttggagaa gtggctttat ctccagagtt attggcaata
    10741 gaaaagaaaa taaactcaat taaacatata cttgaacaac gtaaatttga gacacaaatg
    10801 gcagaacaac gtaagaatga acttattgtt tatcttgcac atgatttaaa aacaccactt
    10861 acatcagtta tagggtatct gacactactt cgagatgaaa gtcagatttc tgaagaactg
    10921 cgaaaaaaat atttatctat ttcgttggat aaggcagagc gtcttgaaga tttaattaat
    10981 gaattctttg aaattacaag gtttaattta tcaaatatat cacttgaata cagtacagta
    11041 agcttaactc gtatgcttga acaactaaca tatgagttta aacctacttt gatgagtaag
    11101 aatttaaaat atacactgaa tgttacacca aatatgatga taaggtgtga tgttaataaa
    11161 atgcaacgtg tatttgataa cttattacga aatgctgttt attatagttt tgaagatact
    11221 actattgaaa taacagctgt acaggaggat gattatataa agcttaaatt tataaatcat
    11281 agcaatacga ttccagagga aaaacttgag cgtatttttg aacaatttta caggttggat
    11341 acatctcgta attcaaacag tggtagagct gggttgggac ttgctatagc taaagaaata
    11401 gtggagcttc ataacgggac aataacagct catagcgaga acaatataat tacctttaag
    11461 gttattattc cgattgtagg aaatttgtaa gaatttaagt ataaaaaaat aggaaattct
    11521 ttaggataaa taaataaaga gcactcttgt tattgatata attactgtat caaaacaaga
    11581 gtgcttttat tttgatacag taattatatc aatagaaaaa tgtgaaaata tattatgtgg
    11641 aacagatgca attgtaagtg aaggttgatt ggatttgaaa tagaaaaagt attttaacat
    11701 gtttctgtag attgtataaa aataaataaa tcaacaaagg agaatcaaag atgaataata
    11761 aaaaaattgc agttatattt ggtggaaact caacagaata tgatgtatca ttacaatcag
    11821 cttttgcagt acttgagaat ttgaatacgg aaaaatatga tattatacca attggaatta
    11881 caagggaggg taattggtat cattatattg gagattataa taatatccag aataacactt
    11941 ggtttgaaag ggatactgat ataattccag ttattgtttc gcagaaccgt gtcaaaaatg
    12001 gtattattga atttttaatt cctgatgctg tttctcagaa tcatattcca aatagtgcta
    12061 ttgaatcatg tgaaaatgat attaaataca ctaaacttga ttttgtgttt cctgtactgc
    12121 atggaaaaaa tggagaagat ggaacagtgc aggggttatt tgaattggca ggtatacagg
    12181 ttattggatg tggtactctt tcttcagcat tatgtatgga caaagacaaa tcacataaac
    12241 ttgttcattc agaaggtatt aaagtaccaa aatcaatatt actaaaatac tcagataaat
    12301 ttaatgtggc tgaactgtca aaagacttaa cttatccatt atttataaaa cctgtgcgtg
    12361 caggttcatc atttggtatt agtaaaattt ataaaaaaga agagttacaa gtagcagtag
    12421 acttggcttt tgaacatgat aatgaagtaa taattgagga aaatattgat ggttttgagg
    12481 tagggtgtgc agttttagga aacaatgact tacttgttgg aagagtagat gaaatagaat
    12541 tgtcaaaagg attttttgat tatacagaaa aatatacatt gaaaagttca aaaattcata
    12601 tgccagctag aattgatttg gattgtgaga aaagaataca agagacagca aaaattattt
    12661 atagaactct tggatgttct ggatttgcta gagtagatat gtttttaact ccatctggtg
    12721 aaattatttt taatgaagtc aatacaattc ctggctttac ttctcatagt cgttatccaa
    12781 atatgatgaa aggtattgga ctgtcttttg aagaaatatt ggacaagata attgaggtgt
    12841 acataaaatg atgaataata ttttattaga taaaaataaa gaagataaaa tgacaaatac
    12901 tatcttattg actaaagata aagtttatga tgggaatcta attctagtaa atgctttttt
    12961 accagttaaa acatctgaag atatagattt aattcctgta gatacaaggt ttccaagtat
    13021 tcttatgaaa cgtgaagcta caaacatttt acaaaatatt ttaaaaagta tatgtggaat
    13081 aaatgaaata gtacctgtaa gtggatatcg tactgcagag gaacaacaag atatatattc
    13141 aagttctctg cgtgacaatg gaaaagactt tactaaaaag tttgtagcac ttccaaatca
    13201 cagtgaacat cagacagggc ttgctattga tttagggtta aagaaagaag ttatagattt
    13261 tatctgccct gaatttcctt ataatggtat ttgtaatgag tttcgtaagg cagcactaca
    13321 ttatggtttt atagagcgtt atcagtgtaa aaaagaagaa ataacaggaa tatctcaaga
    13381 accatggcat tttcgttatg tgggatatcc gcattctgag attatcaata aaatgaatct
    13441 cgctcttgaa gaatatatag aatatattaa gagattttcg tatacaaatt gtttaaaaat
    13501 agaagataaa gaaaaaatta tagaaatctt ttatgtgcct attcatacta aagaagaagt
    13561 gagaatctct atacctgaac aatgtgtata tcaaatatcg ggtaacaata aggatggttt
    13621 tattgtgaca ttttggagaa atagaaagga ctaagaaatg gaggaacaag aatgattagg
    13681 aataaatctt atgcagggct tgattatttt aggattatag ctgcattact tataattgca
    13741 attcatacat ctccattatt atcatatagt aaaatggctg actttgtgtt aactagtata
    13801 attgctcgta ttgctgtgcc attctttttt atgctatcag gcttttttct aatttcaaca
    13861 tataattata attgtaataa actgaaatct tttctaaaaa atgtattatt tatttacggg
    13921 atagctattg taatttatat tcccttaaat atttacactg gatatttttc catgaataat
    13981 ttagtgccca atattattaa ggacattgta tttgatggga ctttatatca tttatggtat
    14041 cttcctgcat caattattgg tgcaagtatt gcatactttc ttgtaaaaaa actaggttta
    14101 aagtactcac tagtaatcac tattgttatt tatgtaattg gtatgtttgg tgatagttat
    14161 tatggttttt tagaaaaaat accactatta aagaatttat atgggtatat ttttgaagta
    14221 tcagattata cacgaaatgg tatatttttt gcacctgtat ttttcatact tggtggaata
    14281 atatctaata aatctaatta tatgtcaact aaaaatagct tgattggatt tcttatatca
    14341 ttcttactta tgttatgtga gggaatgttt ttacataaac taggggtaca gcgtcatgat
    14401 agcatgtata ttatgttatt gccatgtatg tatttcttat ttacagcctt aacatttttg
    14461 aaaggttctc gagctaggtt attgcgaaca tcatcattaa ttatttatat tatacatcct
    14521 atgatgattg ttgttattcg tatgttttct aaaatattcg gaatacaaac tgtcttggtt
    14581 gacaatagcc ttattcatta tatagtggta agtatagcat cttttatagc ttctataatt
    14641 attatattga ttcttaaacc tctaaaaaaa gacttgaaag gagaacataa ggtaaatacc
    14701 aatagagctt ggattgaaat tgatttaaat aatttggaac ataatgtaaa gatgatacaa
    14761 aaagctatgc cagaagattg tgaattgatg gcagttgtaa aagctaatgc ctatggtcat
    14821 agtgcttttg aagtagcgac ttgtgcaaac caaataggtg taaaagcatt tgcagtagca
    14881 acaatagatg aggggattga tttacgtcga tatggaatac taggagaaat attgattctt
    14941 ggatatacta acccaataag ggcaaaggaa cttcataaat acaatcttac acagagtgtt
    15001 attgacctta atcatgctat ctctttaaac aaacagaaat acaacataaa atcacacatt
    15061 aaaattgata caggtatgca cagactgggt tttgatgtta atgatgtgag gtcaatttta
    15121 aaggcattta aattaaaata cttagatata tgtggcatat ttacacactt gtgtgtttca
    15181 gatagtctga aagatgaaga tgtagacttt acaaataaac aaattgaatg tttttataag
    15241 ttaattgatt ttctgttaaa aaaaggtata aaaattccta aagtacatat tcaaagtagt
    15301 tatggttttt ttaattatcc caatcttaag tgtaattatg taagaattgg aattgcatta
    15361 tacgggatat taagttttcc aaatgatacg actaaattgc aacttgattt acgacctgtt
    15421 ttatccttaa aatcacaagt aattcttatt agaaaaatac aaaaagatga tagttttgga
    15481 tatggaagag tctttattgc aagcagagat agcgtaattg ctatattatc tattggctat
    15541 gccgatggta tacctagaaa tttatcctgt ggaaaaagtt acgtaataat aaatggttgt
    15601 agagcagcaa tagtgggtcg aatttgcatg gaccaacttg ctgttgatat tacagatata
    15661 cctaatgtag aagttggtaa tacggcaata ataataggaa gagataattt atctgaatta
    15721 tctgtttctg aagttgcaaa taactcatgt agtatatcga atgaattatt gagcagagta
    15781 ggaagaaggt taaatgttat aaagaagtaa ctcaattaaa tagtaatatt tgttgtactg
    15841 tgtaatttat tttactctga ctagacattt ttagtaatat tatgtctaat atatattttt
    15901 tataacttac atgac
//
LOCUS       DAJMZY010000095        15902 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.096, whole genome shotgun sequence.
ACCESSION   DAJMZY010000095 DAJMZY010000000
VERSION     DAJMZY010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15902)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15902)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15902
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.096"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            complement(90..1637)
                     /locus_tag="OE968_002905"
     CDS             complement(90..1637)
                     /locus_tag="OE968_002905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrite/sulfite reductase"
                     /protein_id="HCP7220166.1"
                     /translation="MDNFKKILLNELPNFKEYSSKFLNGEINKMQYKGFSGGYGVYAQ
                     RDKKSFMIRLRVSAGVLSQYQLNKIYEIAIKHNLDKIHLTTRQAIQLHDLSINSIVDI
                     MEEGIKNDIFTRGGGGNYPRNVGLSPLSGVDPSEVFDVTPYAVATDKYFIKNATTYHL
                     PRKLKVSYSNCYTDTAHCSIQDLGFVATLKNDEPYFRVFLGGGLGKQPKVALELDELI
                     KPKDALYCVEGMIKFFMDYGNYENKNRARVRYMVESLGEELFLEKFKEYYKLEKENGS
                     LELNIEEIDYSKPGVKIDIQDSRLIPQKQDGLYTVYIHPVGGILLTKDLSTLLKELDN
                     VENPMIRLGMTEGLYILNLNGNEAKRILEISKTISCNSQLEQSISCIGVPICQMGIQN
                     SQKMLHEIIDYFRLQNNEEILNKAPKLYISGCLNSCGVHQVGSIGLCGKKKNVDGIST
                     DAFELFVGGSFEIGKTRLGKSLGDFKASDIPEMLYKISDASSGNFYEWVNSNDNILNK
                     ITDKYKI"
     gene            1917..2684
                     /locus_tag="OE968_002906"
     CDS             1917..2684
                     /locus_tag="OE968_002906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HCP7220167.1"
                     /translation="MGEIINALDRALDIILLLYHEKREMGITEISKAMGVYKSTVHRT
                     LVTLENKGFVIQNAENGKYWLGINLYAIGMVVGEKMSLTEIVKPYTKKLNQEFNEVVN
                     VSILEERAQDSPRSIIIHKEYGSNQLLSVNPSVGSSSECYCSAVGKCLMAFNDSIDFE
                     KYRKTPIHKYTEHTIDNWDDMMLFLAKIKEQGYAIDDEELEHGLTCIGAPILDKNNKA
                     IAAISLSGPTIRMREGDFEYKIKRVIETAKSISELFR"
     gene            2967..3164
                     /locus_tag="OE968_002907"
     CDS             2967..3164
                     /locus_tag="OE968_002907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HCP7220168.1"
                     /translation="MEKVKLSVERCKGCYLCIEACKKDAISLSDYTNKKGFVTIKVDE
                     EKCIQCGACYTMCPDLVFEIL"
     gene            3193..4269
                     /gene="vorB"
                     /locus_tag="OE968_002908"
     CDS             3193..4269
                     /gene="vorB"
                     /locus_tag="OE968_002908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate dehydrogenase subunit
                     VorB"
                     /protein_id="HCP7220169.1"
                     /translation="MQSLLIKGNEALAEGAIRGGCRFYAGYPITPQSEILEMMAWRQK
                     EVGGVFIQGESEIASVNMVMGASALGARAMTSSSGPGFSLKQEGIAYWVSAGLPAVVA
                     CVQRYGIGDGFIGAGQDNYWQAVKGGGNGDYHLIVLAPNSVQENMDMAYESFELAEKY
                     MHPVLILSDATIGQMVEPCIAPPMKEYDMDKAPWAAKGTPVGEKNKVITDITYFEDQD
                     TWQKGYIEKMRKVQEDEQRWEEIEIEDAEVVFVAYGISSRIAEGAVRDARAKGMKLGL
                     IRPKTLWPYPRKAFKKLSDSLKGLVTVEMNMMAQMKEDVIIACDNRFPVYSVATAQYM
                     AEVNQLIDFAQQIIDGKAKQEEVF"
     gene            4272..4991
                     /locus_tag="OE968_002909"
     CDS             4272..4991
                     /locus_tag="OE968_002909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate oxidoreductase"
                     /protein_id="HCP7220170.1"
                     /translation="MAKKAPAIMMCENMFCGGCGHSIVDRIIGEVLTEMDICQDTIIC
                     SDIGCNHMFQFSMNVDVVVPPHGKMGAAMAAMKRVRPDKYIFTIAGDGGAYAIGLGET
                     MSAATRNDNVIFLVMNNNMFAMTGGQMAPTTIEGQYTASTPAGRNYADHGSTFDVVKV
                     MGNLDIAYLARGTITNPKEINTTKRYIKKALEKQKEKKGFCLIEVLVPCPTNWGLKPV
                     DAMKRIENELVPKYPLGEFID"
     gene            5004..5543
                     /locus_tag="OE968_002910"
     CDS             5004..5543
                     /locus_tag="OE968_002910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoacid:acceptor oxidoreductase family
                     protein"
                     /protein_id="HCP7220171.1"
                     /translation="MLNEIICAGFGGQGVLTAGKIIMYVAYKAEKKITWFPSYGNEMR
                     GGSANCNVVVSDEKIANPCVKNPDILLGMNSVSVDKYESLMKKNGYMFVNESLVSKDR
                     KYREDINVIKVPVTEIAQNLGNEKAANICMLGAMVKSLDLFTKEEFESGMCEYFENQG
                     KGKFNSKNVEAFEAGYDYE"
     gene            5700..6758
                     /gene="buk"
                     /locus_tag="OE968_002911"
     CDS             5700..6758
                     /gene="buk"
                     /locus_tag="OE968_002911"
                     /EC_number="2.7.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="butyrate kinase"
                     /protein_id="HCP7220172.1"
                     /translation="MKVLVINPGGTSTKISVFQDENEILKKNITHTREDLKNFSKVFD
                     EYDYRKQLIVDILSSENHSINSFDAVVGRGGLMKAIKGGTYTVSEEMIEDMRNEINGE
                     HASNLGALLAKTIADEIGVQSFVVDPVSVDEFDDVSRITGISDIEKASWLHALNHKAV
                     SRKIAQKLGGKYEDYNFIVAHLGSGISIVAHKQGKMIDGSGGRSDGPFSPERSGGLLA
                     YPLIELCYSGKYTHDEMVAKVSSIGGMYDYLGTKDMIEIENRIKEGDEKAKLIMDAFI
                     YQVAKEISMYGASLSGNVDRVILTGGISHSEMVVKGVAEKVSYLAPIEIVPGEMEMEA
                     LALGALRVLNGEEIAKTY"
     gene            6776..7669
                     /locus_tag="OE968_002912"
     CDS             6776..7669
                     /locus_tag="OE968_002912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional enoyl-CoA hydratase/phosphate
                     acetyltransferase"
                     /protein_id="HCP7220173.1"
                     /translation="MLKDFNNLLEEAKKLEPVIVSVAVAEDKEVLKAVKSATDLNIIK
                     PILVGDKDKIESISREIGLKGHEIIGCQNPDESVKKAVEIVKNKEAKVLMKGLVNTSV
                     YMRAILNKETGLRTGRLLSLLAVYELPQYHKLLYCTDSGINVSPNLNQKKDIMTNALL
                     TMKSIGMENPKTAILTANEMVDPKIQSTVDANLLVEMEKSGEIPKCIVEGPIAFDVAF
                     DAHAAEHKGIKSNIAGDVDLLVFPNIEAGNILGKSWLRFNKAKWAGIVLGATNPIILG
                     SRSDTAEIKINSIALACLASQ"
     gene            7699..8907
                     /locus_tag="OE968_002913"
     CDS             7699..8907
                     /locus_tag="OE968_002913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HCP7220174.1"
                     /translation="MKYAKRMDMVKASAIRDSQKKIAQKVASGGTVISFAAGLPDPNL
                     FPIEEISEITQKVLNERGKFALAYGPTKGEDELLDLLVKRMKEEENIDTKAENIIITT
                     GSQQGIALSAMILLEKGDVVVTENPSYLGAINAFRPYECDFLGVDTDEEGMVTDDLDK
                     LLSENSNIKVIYVIPTFQNPTGKTWSLQRRKDFMEVVNKYDVIVIEDNPYGEIRFTPE
                     PLPTLKSLDTKDKVLYLGSFSKVLCPGFRVAWMCGNVDIIDKAELLKQGIDLQSNQFS
                     QVQVIEFLKKYNLNEHIEKIRAEYKKRCLLMLDAMKKHFPEEAKYTEPDGGMFIWVEL
                     PESINVDDLLDKAIDAGVAYVSGESFFANNGPKNTMRLNYTTMSEEQIVKGVEILAEV
                     IKKELNYACE"
     gene            8931..10190
                     /locus_tag="OE968_002914"
     CDS             8931..10190
                     /locus_tag="OE968_002914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCP7220175.1"
                     /translation="MGEKENGIKFGKLMFQLVIIAISWELVYIIPFIQYTLYDPILKA
                     LECTNTQLGFLLTIYGLGNIFGAPIGGWLADRFDYRKIILGSVFLNGVVSFLFAFNMN
                     YPFAVATWVGCAITSLVMNYPSMVKILRVIGKDNQGKVYGFNEAMVGVSGVVMGAIFL
                     YIYTCFATPTLGMRWVMISLGILSIAMCPVLWFVIKDVDIKEEREEAGEKMSAGDFIT
                     VLKSPNTWLVGISIFCVYSFTVTMSYFTPYITSVLGGSVALSGALAIIRQHGLKLFGA
                     PFGGYCADKLKSPTKVLLPIYVFGIAVIVLFLVLPASTPMTIFIALTFVVGILGYMGK
                     GIYYAVQDEVKVPVKYSATTIGIAAALGFSPDVFQFALIGHWIDTYGNKGYTYTFIFQ
                     IAILVIGILSCLYILKVKKRRASKLEA"
     gene            10835..12298
                     /locus_tag="OE968_002915"
     CDS             10835..12298
                     /locus_tag="OE968_002915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine:cation symporter family protein"
                     /protein_id="HCP7220176.1"
                     /translation="MTDLVNTINGIVWSPVLVAMCLCIGLYFSLKLKFFQIRDVKEMF
                     TLLLEGDSSHVGISSFQGFATSMAGRIGTGNIAGVAVAIAMGGPGALVWMCIMATLGS
                     ATAFVESTLAQIYKDEHDGQYRGGPPYYFEKGLGWKKCSVLFSIVAIISYTFFMPGTQ
                     SNTLYLAMNQAFGFSKMTIAVASSIALAIIIFGGIKRIGLFAEKVVPIMGGAYLIMTL
                     VIIITNISLVPEAIVTMFKSAFGFGSVFGGMLGSAISWGVKRGIYSNEAGEGSGTYGA
                     AAAEVSHPAKQGLVQAFSVYVDTLLICMATGIMIVITGMYNVTGVCTALPGVEPGPQY
                     VQSAINTLHPQLGDIFIAIVLLLFTFTTLLAFSYMMETNVSYLVTRIKAEKHEKYIIN
                     VCRFMLIACAAMCCFIEPLTSWALGDICIGVLTYINLIAIFTLKKPAIKAYYDYIRQK
                     KMGIKRSDRTFNPIELDIRNAEFWENRYLKEDKHELN"
     gene            12354..13490
                     /locus_tag="OE968_002916"
     CDS             12354..13490
                     /locus_tag="OE968_002916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HCP7220177.1"
                     /translation="MKERIIQVADSKKEKILGLCQSLYDEPEIALQEYKSAKKISEFL
                     REEGFDVEENLAGMATAFKATKKNGDGPKIAFIAEYDALPGNGHACGHHLIASMGVGA
                     GIALSSILDTYKGEVSIIGTPAEETGDGKPYLIEHGVFDGYDAAMMIHPNSKTCVTPE
                     IIAIGGLDFIFTGKASHAGAKPYNGINALDAVVLLYNNINALRQQLVDGTRIHGIILE
                     AGTAANVIPDMGKVRLEIRAKEQNYFDEVVEKVKNCARGAAIATGCELEFYHFEPTCQ
                     GLNENKVLVDIFTKIMEEFGIYEDEQVMLGSTDMGNLSQIMPCIHPLMKFSENGEELH
                     TKEFLEASINSYAKDRVIDGIKILALTGFNLFENPELLKKMKEE"
     gene            13726..14841
                     /locus_tag="OE968_002917"
     CDS             13726..14841
                     /locus_tag="OE968_002917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="linear amide C-N hydrolase"
                     /protein_id="HCP7220178.1"
                     /translation="METLEVRNIELSGTNYEIGYRLGELVANMPEIIEGQINKSNLVS
                     KKEEKEMIELFDKYCPGLNEELQGFADAIQVNCNQILYYTMTYLKPGCSQVALAPELT
                     ENGHVLFARNFDFSHNMEDFVLCKTKVNGKYAHIGTTVMQFGRGEGMNECGLGVSQSS
                     CGIPVGNSDGLRKPAIVGLQFWAVIRYLLENCKDVDEALEYLKDMPIAYNINLLLADK
                     SGNIALVETLDGKKEVNIINSLESKREYFLHSTNHTHIDKLHKLEPQSMKNSIHRYKL
                     IKEYINKSKKIGEKELMNLLSSKYPNGLSCNYYNDFFGTLKSIVMDLNIGKFNILWGG
                     LENKWESYYLKNDIKSITQRININIEKAPSDFFDFIE"
     gene            14993..15862
                     /locus_tag="OE968_002918"
     CDS             14993..15862
                     /locus_tag="OE968_002918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HCP7220179.1"
                     /translation="MDYLKYFKKAVMYIENNLHENITVNDVAKETGYSYYHLTRLFKS
                     MFGESVGSYIKKRRLVSSTKELLYSDKKVIDIAIGSGFESSEAFSRAFKSIYKVSPIE
                     YRKNRIDVFVGKKKKLELDFMRHLVGNITIKPVIKEIEKIKVIGIKDKVILENNSLPD
                     LWEKFRKVHHIVPNTLPSKRVFGICEAISEIHLVSESMEFNEIIGLEVNSYDVIPNSF
                     VSKTIKEGKYAIFTHTGSLDNLDKTYEYIWGTWFLSSKEELDIRDDFEVYDERFLGPS
                     NVNSQIDIYIPIK"
BASE COUNT         6074 a         1796 c         2934 g         5098 t
ORIGIN      
        1 atatatttga tttcatagaa aaagagtgtc tcataaacta aaaagttcat tttgagacac
       61 ccatgttttt tgtaagtaaa tataataaat tatattttat acttatcagt tattttgttt
      121 aaaatattat catttgaatt tacccattca taaaaattgc ctgaagatgc gtccgatatt
      181 ttataaagca tttcaggaat atcactagct ttaaaatctc caagtgattt tcccaatcta
      241 gtcttaccta tttcaaaact gcctccaaca aataattcaa atgcatctgt agatatacca
      301 tcaacattct tctttttacc acataaacct atgctaccaa cttgatgaac accacatgaa
      361 tttaaacatc ctgatatata taacttaggt gctttattta aaatttcttc attattttgt
      421 aatctaaaat aatctatgat ttcatgtaac attttctgac tattttgtat gcccatttga
      481 caaattggaa cacctatgca agatatactt tgttctaatt gagaattaca actaatagtt
      541 ttacttattt ctaatattct ttttgcttca tttccattta aatttaaaat atataatccc
      601 tctgtcattc ctagtctaat cataggattt tcaacattat ctaattcttt aagtaaagta
      661 cttaaatcct ttgttaacaa aatacctcca actggatgta tatatacagt gtataaacca
      721 tcctgttttt gaggtattag tctagaatct tgtatatcta ttttaactcc aggtttagag
      781 taatctattt cttcaatatt gagttcaaga ctaccatttt ctttttctaa tttatagtat
      841 tctttaaatt tttctaagaa tagttcttca ccaagtgatt cgaccatata tctaacccta
      901 gctctgtttt tattttcata atttccataa tccataaaga atttaatcat accttcaaca
      961 caatataagg cgtctttcgg ctttataagt tcatcaagtt ctaaagcaac tttgggttgt
     1021 ttacctagac ctccacctaa gaaaactctg aaatatggtt catcattttt caaagtagca
     1081 acaaatccta agtcttgtat actacaatga gcagtatctg tgtaacaatt agaataagaa
     1141 acttttaatt ttctaggtaa atggtatgta gtagcatttt tgataaaata tttatcagta
     1201 gcaactgcat atggagtaac atcaaagact tcactagggt caactccaga taatggagat
     1261 aatccgacat ttctaggata attaccacca ccacctctag tgaatatatc attttttatt
     1321 ccttcttcca tgatatcaac aattgaattt atagataaat cgtgtaattg tatagcttgt
     1381 ctagttgtta agtgtatctt atctaagttg tgtttaatag ctatttcata gattttatta
     1441 agttgatact gagataaaac tccagcagat actctaagtc ttatcataaa agattttttg
     1501 tctctttgag cataaacacc atatccacca gaaaatccct tatattgcat tttatttatt
     1561 tctccattta aaaattttga agaatattct ttaaaattag gtagttcatt taacaatatc
     1621 tttttaaaat tatccattat ttcacctcat tgttagtctt gtataaaaat atatctattg
     1681 tataatagat atatatatta ttatctagtc aggataaaaa tataacagaa taattctatt
     1741 aaaagtaaga ataataagga catagtgagt attttgtttt tattttacaa attaagtata
     1801 atatttttgt tttataaaat ataattaaga taaatagata attttgtaat tttaatatat
     1861 aatatttagt agagtgtggg agtagcactt aatatttgca ggaggagttt ttgtatatgg
     1921 gagaaataat aaatgcatta gatagagccc tagacataat tttgctgtta tatcatgaaa
     1981 agagagaaat gggaataact gaaataagta aggctatggg agtatataaa agtactgtac
     2041 atagaacttt ggttactctt gaaaacaaag gttttgttat acaaaatgca gagaatggta
     2101 agtattggct aggaataaat ttatatgcaa taggtatggt tgtgggagaa aaaatgtcat
     2161 tgactgaaat agtaaaacca tatacgaaaa aattaaatca agaatttaac gaagtagtta
     2221 atgtatctat attagaagaa agagctcaag attctccaag aagtatcata atacataaag
     2281 agtatggttc aaatcaatta ctttcagtaa atccatccgt tggttcaagt agtgaatgtt
     2341 attgttcagc agttggtaaa tgtcttatgg catttaatga ttctatagat tttgaaaaat
     2401 atagaaaaac accaatacac aagtatacag aacatacaat tgataattgg gatgatatga
     2461 tgcttttttt agcaaaaata aaagaacaag gatatgctat agatgatgaa gaactagaac
     2521 atggactaac ttgtattgga gcacctatct tagataaaaa taataaagct attgcagcca
     2581 taagtttgtc aggtccaact ataagaatga gagaagggga ctttgagtat aagattaaaa
     2641 gagttataga aactgcaaaa agtatatctg aactttttag atgattttta atctcgataa
     2701 taaaaatagg ctatatttaa attgttattt gtaaatatca gtttaaatgt agcctatttt
     2761 tctttaatct aaaattaaat attcttaaaa tttaaaatgt tattgaaata tataagcgaa
     2821 tgtgttatct tttaattaag caataaaaat agaacaaggt tctatactat agaacaaaat
     2881 tgatgcatat atagtattta tacaaaatat aaatattata tatttaaaat taagtaaaaa
     2941 tattacataa aggggagatt tgagaaatgg aaaaagtcaa gttgagtgtt gaaagatgta
     3001 agggatgcta tctttgtatt gaagcttgca aaaaagatgc aataagtctt tctgactaca
     3061 caaataaaaa aggctttgta actattaaag tcgatgaaga aaaatgtatt caatgtggcg
     3121 cttgttatac aatgtgccct gatttagtat ttgagatatt ataaattatt tttattagag
     3181 gggagaaaag gtatgcaaag tttattaatt aaaggaaatg aagctttagc agaaggtgct
     3241 atacgtggtg gttgcagatt ttatgcaggt tatccaataa cgccacaatc agaaatatta
     3301 gaaatgatgg catggagaca aaaagaagtt ggaggagtat ttatccaagg tgaatcagaa
     3361 atagccagtg taaatatggt tatgggagca agtgcacttg gagcaagagc tatgacttct
     3421 tcatctggtc caggattttc attaaaacaa gaaggtattg catattgggt atcagctggt
     3481 ttgccagcag ttgtagcatg tgtgcaaaga tatggtatag gtgatggatt tataggagct
     3541 ggtcaagata attattggca agcagtaaaa ggcggtggaa atggagatta tcatttaatc
     3601 gtgttagcac ctaatagtgt tcaagaaaat atggatatgg catatgaatc ttttgaattg
     3661 gctgaaaaat atatgcatcc agtacttata ctttctgatg ctacaatagg tcaaatggta
     3721 gaaccttgta tagcaccacc aatgaaagaa tacgatatgg ataaagctcc atgggctgca
     3781 aaaggaacac ctgtaggaga aaaaaataaa gtaataactg atataacata ttttgaagac
     3841 caagatacat ggcaaaaagg gtatatagaa aaaatgagaa aagttcaaga agatgaacaa
     3901 agatgggaag agatagaaat agaagatgct gaagtggtat ttgtggcata cggtatttca
     3961 tcaagaatag cagaaggtgc agttagagat gctagagcaa aaggaatgaa attaggtcta
     4021 ataagaccaa aaacattgtg gccttaccca agaaaagcat ttaagaaatt aagtgattca
     4081 ttgaagggac ttgtaacagt tgaaatgaac atgatggcac agatgaagga agatgtaatt
     4141 atagcatgtg ataatagatt tccagtatat tcagtagcaa cagctcaata tatggcagaa
     4201 gtaaatcaat taatagattt tgctcaacag attatagatg gaaaagctaa gcaagaggag
     4261 gtattttaat tatggctaaa aaagcaccag caataatgat gtgtgaaaat atgttctgtg
     4321 gaggctgtgg acactctata gtcgatagaa ttattggaga agtattaaca gaaatggata
     4381 tatgtcaaga tacaattata tgttcagata taggttgtaa tcatatgttt caatttagta
     4441 tgaatgtaga tgttgtcgtt ccacctcatg gtaaaatggg agcagcaatg gcagctatga
     4501 aaagagttag accagataaa tatatattta caatagctgg agatggtgga gcttatgcaa
     4561 tagggcttgg agaaactatg tcagctgcta ctagaaatga taatgtaata tttcttgtta
     4621 tgaacaataa tatgtttgca atgacaggag ggcaaatggc tccaactact atagaaggtc
     4681 aatatacagc ttctactcca gcgggtagaa attacgcaga tcatggttca acatttgatg
     4741 ttgtaaaagt tatgggaaat ttagatatag catatctagc aagaggaaca ataactaacc
     4801 ctaaagaaat aaatacaaca aaaagataca tcaaaaaagc tctagaaaaa caaaaagaaa
     4861 agaaaggttt ttgcttaata gaagtgcttg taccatgtcc aacaaactgg ggattaaagc
     4921 cagtagatgc tatgaagaga attgaaaatg aacttgttcc aaagtatcca cttggagaat
     4981 ttattgatta gggaggaaat aatatgttga atgaaattat atgtgctggt tttggaggac
     5041 agggagttct tacagcagga aaaattataa tgtatgttgc atataaggca gaaaagaaaa
     5101 ttacatggtt cccatcttat ggaaatgaga tgaggggagg aagtgcaaat tgcaatgttg
     5161 ttgtaagtga tgaaaaaatt gcaaatcctt gtgtaaaaaa tccagatata ctattgggaa
     5221 tgaacagcgt atcagtagat aagtatgaaa gtttaatgaa aaaaaatggt tatatgtttg
     5281 tcaatgaatc actagtaagt aaggatagaa agtacagaga agacattaat gttataaaag
     5341 tacctgttac tgaaatagca caaaatttag gcaatgaaaa agctgctaac atttgcatgt
     5401 taggtgctat ggtaaagagt ttggatttat ttacaaaaga agaatttgaa agtggtatgt
     5461 gtgaatactt tgaaaatcaa ggcaaaggta aattcaattc taaaaatgta gaagcatttg
     5521 aagctggata cgactacgaa tgaatatttt aaatatttaa aataattatt gaaatactta
     5581 tttttatatg ttagtattta attaataaaa tatagaacgt cgttctgaac aataggacga
     5641 agtctttagg tcggaataca agaacgacgt tctgtatagt agaactaggg ggtgttaaat
     5701 tgaaagtttt agtaataaat cctggtggta catccacaaa aatttctgtt ttccaagatg
     5761 aaaatgaaat tttgaaaaaa aatataaccc atacaagaga agatttaaaa aatttttcta
     5821 aagtatttga tgaatatgat tatagaaaac aactgatagt agatatttta agtagtgaga
     5881 atcatagtat aaattctttt gacgcagtag ttggtcgtgg tggacttatg aaggctataa
     5941 aaggtggtac ctatactgtg agtgaagaaa tgattgagga tatgagaaat gaaataaatg
     6001 gggaacatgc atcaaattta ggtgcattat tagctaaaac tatagctgat gaaataggag
     6061 tacaatcatt tgtagtagac ccagtttctg tagatgaatt tgatgatgta tcgaggatta
     6121 caggaatatc agacatagaa aaagcaagtt ggttacatgc attaaaccat aaagctgttt
     6181 caagaaaaat tgcacaaaaa ctagggggaa aatacgagga ttataacttt attgtagctc
     6241 atttaggttc aggaatatcg attgtagcac ataaacaagg caaaatgatt gatggaagtg
     6301 gtggtaggtc tgatggtcca ttttctccag aaaggagtgg tggattactt gcatatcctc
     6361 ttatagaatt gtgttactcc ggaaaatata ctcatgatga aatggtcgca aaagtaagtt
     6421 cgattggggg aatgtacgat tatttaggaa caaaggatat gatagaaatt gaaaacagaa
     6481 tcaaggaggg tgatgaaaag gcaaaactta taatggatgc atttatttat caagtagcaa
     6541 aagaaatttc tatgtatgga gcttcacttt cagggaatgt agatagagtt atcttgacag
     6601 gagggatatc tcactcagaa atggtagtca aaggagtagc agaaaaagtt tcatatctag
     6661 ctccaataga gatagtacca ggagagatgg aaatggaggc acttgctcta ggggcactta
     6721 gagtacttaa tggagaagaa atagcaaaaa cttattaata tttaggagaa agagtatgtt
     6781 aaaagatttt aataatttat tagaagaggc taaaaagctt gaacctgtta ttgtaagtgt
     6841 tgctgttgca gaagacaaag aagtattaaa ggctgtgaaa tcagcaacag atttaaacat
     6901 tataaagcca attcttgtag gagacaagga taaaatagaa agtatatcaa gagaaattgg
     6961 attaaaaggt catgaaataa taggttgtca aaatcccgat gaatcagtta aaaaagctgt
     7021 agagatagtt aaaaataagg aagctaaagt tcttatgaag ggattagtaa atacaagtgt
     7081 ctatatgaga gctatattaa ataaagaaac gggtcttaga acaggaagat tattaagttt
     7141 gcttgcagta tatgaattac ctcaatatca taaacttctt tattgtactg atagtggaat
     7201 aaatgtatcg ccaaacttaa atcaaaaaaa agatataatg acaaatgcac ttcttactat
     7261 gaaaagtata ggcatggaaa atcctaaaac tgcgatactt actgcaaatg aaatggtaga
     7321 ccctaagata caatctacag tggatgccaa cctacttgta gagatggaaa aatcgggaga
     7381 aataccaaag tgtatagtgg aaggtccaat agcatttgat gtagcatttg atgcacatgc
     7441 agcagaacat aaaggtatta aaagtaatat tgctggtgat gttgatttat tagtatttcc
     7501 aaatatagaa gcagggaata tattaggaaa gtcatggctt agatttaata aagctaagtg
     7561 ggcaggtata gttttaggag caacaaatcc gataatttta ggttcacgtt ctgacacagc
     7621 tgaaataaaa ataaattcaa tagcattagc gtgcctagca tcacaataag aaattattat
     7681 taaggaggaa aaagtattat gaaatatgca aaaagaatgg atatggtaaa agcttcagct
     7741 ataagagatt ctcaaaagaa aatagctcag aaggtagcaa gtggtggaac tgttatatct
     7801 tttgctgcag ggcttcctga cccaaattta tttccaatag aagagataag tgaaataact
     7861 caaaaagtac ttaatgaaag gggaaaattt gccctagcat atggacctac taaaggtgaa
     7921 gatgagttgt tagatctatt agtaaaaaga atgaaagaag aagaaaatat tgatacaaaa
     7981 gcagaaaata ttataataac tactgggtca caacaaggga tagcattaag tgctatgatt
     8041 ttattagaaa agggagatgt agtagttaca gaaaatccaa gttacttagg tgcaataaat
     8101 gcatttagac cttatgaatg tgatttttta ggagtagata cagatgaaga aggaatggta
     8161 acagatgatt tagacaaatt attatctgaa aattctaaca taaaggtgat atatgtaata
     8221 ccaacatttc aaaaccctac aggaaaaaca tggtctttac aaagaagaaa agattttatg
     8281 gaagtcgtga ataaatatga tgtcatagta atagaggata atccttatgg agaaataaga
     8341 tttacaccag aacctctacc tacacttaaa tctcttgata ctaaagataa agtattgtac
     8401 cttgggtcat tttcaaaggt attatgtcca ggatttagag ttgcttggat gtgtggtaat
     8461 gtagacatca tagataaggc agaactttta aaacaaggta tagatttaca gtcaaatcaa
     8521 ttttcgcaag tacaagtaat agaattttta aagaaataca acttaaatga acatatagaa
     8581 aaaataagag cagagtataa gaaaagatgt ctgctaatgt tagatgctat gaagaaacat
     8641 ttcccagagg aagctaaata tacagaacca gatggaggaa tgtttatatg ggttgaactt
     8701 cctgaaagta taaatgtaga tgatttatta gataaagcca ttgatgctgg agttgcttat
     8761 gtttctggag agtccttctt tgcaaataat ggtccaaaaa atactatgag acttaactat
     8821 acaacaatgt cagaagaaca aatcgttaaa ggtgttgaga tacttgcaga agttataaaa
     8881 aaagaactca attatgcttg tgaataaata taaaaagtga gggtttaaat atgggagaaa
     8941 aagaaaacgg tataaagttt ggaaagttaa tgtttcaact tgttattata gcaatatctt
     9001 gggaattagt ttatattata ccatttatcc aatatacatt atatgatcca attctaaaag
     9061 cattagaatg tacaaacact caactaggtt ttctacttac aatttatggg ttaggtaata
     9121 tatttggagc tcctatagga ggctggttag cagatagatt tgattataga aagataattt
     9181 taggttctgt atttcttaat ggagtagtat catttttatt tgcatttaat atgaactatc
     9241 catttgcagt tgctacttgg gtaggttgtg caatcacatc attagttatg aactatcctt
     9301 ctatggtaaa aatacttaga gttataggaa aagataatca aggtaaggtt tatggattta
     9361 atgaagctat ggttggagtt tctggagtag taatgggagc aatattctta tatatttata
     9421 catgctttgc aactcctaca ttgggtatga gatgggtaat gatatcttta ggaatattat
     9481 caatagcaat gtgtccagta ttatggtttg taattaaaga tgtagatatt aaagaagaaa
     9541 gagaagaagc aggtgaaaaa atgtctgctg gtgattttat aacagtacta aaatcaccaa
     9601 atacttggct agtaggaata agtatattct gtgtatattc attcacagtt acaatgtctt
     9661 attttacacc atatataaca tctgtacttg gaggttctgt agcattatct ggtgcattag
     9721 caataataag acagcatggt ctaaaattat ttggagcacc atttggagga tattgtgcag
     9781 acaaattaaa atctcctaca aaagtacttt taccaatata tgtatttggt atagcagtaa
     9841 tagttttatt cctagtatta cctgcatcaa ctccaatgac tatattcata gctttaacat
     9901 ttgtagtagg tatattaggt tacatgggaa aaggtatata ttatgcagta caagatgaag
     9961 taaaagttcc agttaaatat tcagcaacta ctataggtat agctgcagct ttaggatttt
    10021 caccagatgt attccaattt gcattaatag gacactggat agatacttat ggcaataaag
    10081 gttacacata tacatttata ttccaaatag caattctagt tattggaata ctatcttgtt
    10141 tatatatatt aaaggttaaa aagagaagag caagtaaatt agaagcttaa atattcaatt
    10201 tggtaattaa gtatatataa atacaatact tattttgatg aatgtgattg tataaataac
    10261 ataaaaaata tcaatagatt aagttttata ataatgttta gagaataaag tataaaaatc
    10321 aaaatgttat caagttttct aggttttaac ataaagttac ccctgaaggt gtaaaattga
    10381 gtggcaatta ttatctattt tcttacctac ataaacctat ttaatttaaa ttctaagaga
    10441 ttttaaaaat agatggtagt tgtactcaat tttaaacctc ataataaata cgaaaattta
    10501 aaatctaact agatactatt taattatata ttaataaata tatattgtac tatttatata
    10561 ataataattt caggcttttc attatatgta ttccaattta tattgtttga ttattattca
    10621 aacacacgtc gttaaaaatt ttataaattt atgtttagat atgattaata ctcttgattt
    10681 tagaaataaa tatttgtaga ttgtagatta aagataatat aaataaatag aaggtagatt
    10741 ttttagatat attaatataa agattatata aaatattgaa atatagctgt ttaaattatt
    10801 gtctataaat ataaaatgaa tggtggtgag ttaagtgacc gatttagtta acaccattaa
    10861 tggaattgtt tggtcacccg tattagttgc aatgtgtttg tgtataggat tatatttttc
    10921 attgaaatta aaattttttc aaataagaga tgtaaaagaa atgtttactc tcttgcttga
    10981 aggagatagt tctcatgttg gtatatcatc atttcaaggt tttgctacat ctatggctgg
    11041 aagaataggg actggaaata tagctggtgt agctgtagca atagcaatgg gaggtccagg
    11101 agcattagta tggatgtgta taatggctac attaggttca gcaactgcat ttgtagaatc
    11161 tactctagct caaatatata aagatgagca tgatgggcag tatagaggag gacctccata
    11221 ttattttgaa aaaggtcttg ggtggaaaaa gtgttcagtt ttattttcaa tagttgcaat
    11281 aataagttat acatttttta tgcctggtac acaatcaaac actttatatc tagcaatgaa
    11341 tcaagcattt ggattttcaa aaatgacaat agcagtagca tcttctattg cattagcgat
    11401 aataattttt ggaggaatta aaaggattgg tttatttgct gaaaaagtag tacctataat
    11461 gggtggagca taccttatta tgacattagt aataattata acaaatatta gtttagttcc
    11521 agaggctatt gtaacaatgt ttaaatctgc atttggattt ggttcagttt ttggaggaat
    11581 gctaggttca gcaatatctt ggggagtaaa aagaggtata tactcaaatg aagcaggaga
    11641 aggttctggg acttatggtg cggcagcagc agaagtgagt catccagcca aacaaggatt
    11701 agttcaagca ttttctgttt atgtagacac attattaata tgtatggcta caggtattat
    11761 gattgtaata acaggaatgt ataatgttac aggtgtttgc acagcactgc caggtgtaga
    11821 accgggacca caatatgtac agagtgcaat aaatacatta catccacaat taggtgatat
    11881 ttttatagca atagttttat tattatttac atttacaact ttattagcct tctcatatat
    11941 gatggagact aatgtatctt acttagtaac tagaattaaa gcagaaaaac atgaaaagta
    12001 cataattaat gtctgtagat ttatgcttat agcatgtgca gcaatgtgtt gttttataga
    12061 accacttaca agctgggcat taggtgatat atgtataggt gtattaacat atataaattt
    12121 aattgccatc tttacactaa aaaaaccagc tataaaggca tattatgatt atataagaca
    12181 gaagaagatg ggaataaaaa ggagtgatag aacttttaac cctatagagt tagatataag
    12241 aaatgctgag ttttgggaaa atagatactt aaaagaggat aagcatgagt taaattaaag
    12301 ttataataaa atataaaaat tactaaataa atttagtggg aggtaagatt ggtatgaaag
    12361 aaagaataat acaagtggct gattcaaaga aagaaaaaat tctagggcta tgtcaatctt
    12421 tatatgatga accagaaatt gctttgcaag aatataaatc tgctaaaaaa atatcagaat
    12481 ttttaagaga agagggtttt gatgttgagg aaaacttggc aggtatggct acagctttta
    12541 aagcaaccaa gaaaaatgga gatggtccta aaatagcatt tatagcagaa tatgatgctc
    12601 ttccaggcaa tggacatgca tgtggacatc atttaattgc atctatggga gttggagctg
    12661 gaatagctct ttcaagtata ctggatactt acaagggaga agtaagtata attggaacac
    12721 ctgctgaaga aactggagat ggaaagcctt acttgataga acatggtgta tttgatggct
    12781 atgatgcagc aatgatgata catccaaatt caaaaacttg tgtaacacct gaaattatag
    12841 caataggagg tctagatttc atatttactg gaaaagcatc tcatgcagga gctaagccat
    12901 ataacggaat aaatgcttta gatgcagtag tattactata taataatata aatgcactaa
    12961 gacaacaatt agtagatgga acgagaatac atggtattat actagaagca ggaactgctg
    13021 caaatgtaat acctgatatg ggaaaagtaa gattagagat aagggcaaaa gaacaaaatt
    13081 actttgatga agtagtagaa aaagtgaaaa attgtgctag aggtgctgca atagccactg
    13141 gatgtgaact tgaattttat cactttgaac caacttgcca aggattaaat gaaaataaag
    13201 ttttggtaga catatttaca aagattatgg aggaatttgg aatatatgaa gatgaacaag
    13261 taatgttagg ttcaacagat atgggaaatt taagtcaaat aatgccatgt atacatcctt
    13321 tgatgaagtt ttctgaaaat ggagaagaac tacatacaaa agaatttttg gaggcttcta
    13381 taaattcata tgcaaaagat agagtaattg atggtataaa aatattagct ttaacaggat
    13441 ttaatttatt tgaaaatcca gagttattga aaaaaatgaa ggaagagtag aacttagact
    13501 atttttaatt atactcttta aaataagaag agtgtctcaa aatgaacttt ttagtttatg
    13561 agacactctt ttttgtatga aattaaatat atttttatta ttttaacaat gaaaaagagg
    13621 cttatctgtt tttatatgac cttttttaac ttgtagcaca aaatatcatg aatgattaca
    13681 attcgaatga taaaatcgat tataagatat ataggagggg tacatatgga aactttagaa
    13741 gtaagaaata ttgaattgag tggtacaaat tatgagatag gatacagact aggagaattg
    13801 gttgctaata tgccagagat aatagaaggt cagattaata aatctaatct ggtaagcaaa
    13861 aaagaagaaa aagagatgat agagttgttt gataaatatt gtccaggtct taatgaagaa
    13921 ttgcaaggtt ttgctgatgc aattcaagtg aattgtaatc aaattttata ttatactatg
    13981 acttatctta aaccaggttg tagtcaagtt gcattagcac cagaattaac tgaaaatggg
    14041 catgtactat ttgcacgtaa tttcgatttc tcacacaata tggaggattt tgttttatgt
    14101 aaaactaagg taaatggaaa atatgcacat ataggtacta ccgttatgca atttggaaga
    14161 ggtgaaggta tgaatgaatg tggcttaggt gtaagtcagt catcatgtgg tattcctgta
    14221 ggcaattcag atggtttaag aaaaccagca attgtaggtt tacagttttg ggctgttatt
    14281 agatatttgt tagaaaattg caaagatgta gatgaagcat tagaatattt aaaagatatg
    14341 ccaattgcat acaatattaa tttattgctt gcagataagt ctggaaacat tgcacttgtg
    14401 gagactttag atgggaaaaa agaagtaaat ataatcaata gtttagaaag taaaagagaa
    14461 tattttttac actctactaa tcatacacat attgataaac ttcataaatt agagccacaa
    14521 tcaatgaaaa attctattca tagatataaa ttaattaaag aatatataaa taagtctaaa
    14581 aaaattggag agaaagagtt aatgaattta ttgtcttcaa aatatccaaa tggcttatct
    14641 tgtaattact ataatgattt ttttggaact ttaaaaagta tagttatgga tttaaatata
    14701 ggaaagttta atattttatg gggtggacta gagaataaat gggagagcta ctatttaaaa
    14761 aatgacatta aatctataac acagaggata aacataaata ttgaaaaagc accatctgac
    14821 ttttttgatt tcattgaata aaaaatgtat ttaattattc taaataatta ggatatataa
    14881 atcaactaaa agtttttatt tatcgtattg aattagttat aatattttag tatagtaaaa
    14941 aatagtgcta ttttacatat ttaaagagtt taagtagaag agaggtgcca tattggatta
    15001 cttaaagtat tttaaaaaag ctgtaatgta tattgagaat aatttacatg aaaatataac
    15061 tgtaaatgat gtggcaaaag aaactggata ttcttattat catttaacac gcttatttaa
    15121 gtctatgttt ggtgagagtg taggaagtta tataaaaaaa agacgattag taagtagtac
    15181 aaaagaactt ttatatagtg ataaaaaagt gatagatata gctattggta gtggatttga
    15241 atcttcggaa gcatttagca gagcatttaa atctatatac aaggttagcc ctatagaata
    15301 tagaaaaaat agaattgatg tatttgttgg taaaaagaaa aaattagagt tagattttat
    15361 gagacatctt gttggaaata taacgattaa accagttata aaagaaatag aaaaaataaa
    15421 ggtaataggt ataaaggata aagtaatttt agaaaataat tcattacctg acttgtggga
    15481 gaaattcaga aaagtacatc atattgtccc aaatactttg ccatcaaaga gagtttttgg
    15541 aatctgtgaa gcaatctctg aaatacacct agttagtgaa agtatggaat ttaatgagat
    15601 aataggactt gaagttaata gttatgatgt gattccaaat tcatttgttt caaaaactat
    15661 taaggaagga aagtatgcta tatttactca tactggtagc ttagataatt tagacaaaac
    15721 ttatgaatat atatggggta cttggttttt aagttcaaaa gaagaacttg atataagaga
    15781 tgattttgaa gtatatgatg aacgattttt aggtcctagt aatgtgaact cacaaattga
    15841 tatttatata cctataaaat aatctataag aaaactaaaa aataatttga ttaagaaata
    15901 ga
//
LOCUS       DAJMZY010000096        15735 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.097, whole genome shotgun sequence.
ACCESSION   DAJMZY010000096 DAJMZY010000000
VERSION     DAJMZY010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15735)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15735)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15735
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.097"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            complement(146..526)
                     /locus_tag="OE968_002919"
     CDS             complement(146..526)
                     /locus_tag="OE968_002919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HCP7220180.1"
                     /translation="MCLKKLSKLELVIMKFIWNLDIKTNSYEIIDYMKEEHNLPEKVA
                     LKTLSKLSKKRFLYVQETGKCMYYTVAIKEKAYLEFISRNVQNLLKNNFIRNLLVSFH
                     EEELTEEKIKSLENWVVNWEEAYV"
     gene            complement(727..1920)
                     /locus_tag="OE968_002920"
     CDS             complement(727..1920)
                     /locus_tag="OE968_002920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HCP7220181.1"
                     /translation="MLTSLALIFLLGMASGGIFKRIKLPNLLGMLLTGIILGPYVLNL
                     IDNSILDISSDLRKIALIIILTRAGLSLDINDLKKVGRPAVLMCFIPATFEIIGMIVL
                     APKLLGVSILEAAVMGAVVGAVSPAIIVPKMLKLMEEGYGTEKSIPQMLLAGTSIDDI
                     FVIVMFTVFTGLAQGNSISAISFLQIPVSIILGVIVGAVIGIYLAVFFKKVHMRDSAK
                     GVLLLSISFLMISLETALEGIVPFSGLLAVMSIGIFLQIKYRVVARRLSIKYSKLWVG
                     AEILLFVLVGATVDISYAFKAGIGAVILIFGVLLFRMVGVFFCLIKTNLTIKERLFCM
                     IGYIPKATVQAAIGGVPLAMGMASGQLILTLAVLAILITAPLGAFGIDVTYKKLLTSV
                     KGENK"
     gene            complement(1983..3239)
                     /locus_tag="OE968_002921"
     CDS             complement(1983..3239)
                     /locus_tag="OE968_002921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HCP7220182.1"
                     /translation="MIEKFKTLIWIKMIIRIKSVYKTYGGLFFLGLIGIPVGAIIGLI
                     DTIFGTVLLKVTDIRETYPMYLIPFLAVVGVVIAYCYFKFGGKSSKGMNLIFEVGHGE
                     EEIIPLRLVPFIISGTWLTHLFGGSAGREGVAVQIGATFSHWVGKRLPIKNASSIFLV
                     TGMAAGFAGLFETPIAAILFAMEVLVAGSLEYQSLFPAFTASFTASAVSKALGLEKFS
                     FALSSKVVFDLSIFWKLIVLGIIFGMVGGAFAWCLKLSKRKIGNRLKNPMIRIAIIGV
                     CLSVLFLLFYKGRYSGLGTNLIQNSFYGGEIYSFDWLLKFILTILTLSAGFQGGEVTP
                     LFSIGASLGVLLAGFFNLPIELVAALGYASVFGSATNTFFAPVFIGAEVFGYSYLPYF
                     FVVCAISYIFNMDKSIYSLQKISTKQ"
     gene            complement(4035..4769)
                     /locus_tag="OE968_002922"
     CDS             complement(4035..4769)
                     /locus_tag="OE968_002922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HCP7220183.1"
                     /translation="MNLAKGLDVLKISSNVFGEDKVMYIPVIYTEDDATLIDTGLPGQ
                     GDLIIDALNKSNTSFDKLKNIIITHHDIDHIGNINYLREKSKNNIKVYAYKSEISYIT
                     GEETPFKLYMLEQMVDKIDDKMLSMLNVMGLGFKSSYTKVDVSLDNHEKLNLGEEIEV
                     IHTGGHTRGHICLYLKESKVLIAGDLLQVENGELKPVDVMYSNKQELKDAIKNISNYD
                     IETIVFSHGGLYQRNIIGTLKNLIIE"
     gene            complement(5775..6413)
                     /locus_tag="OE968_002923"
     CDS             complement(5775..6413)
                     /locus_tag="OE968_002923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 transporter permease"
                     /protein_id="HCP7220184.1"
                     /translation="MLIHLVKKDILIVKKYVLLILFIAIGIPLFILWRLPPFAQILGF
                     VLSIIFSEFMLCQYLLLKESQYSKASVLLCSTPYPRRGLVQSKYVLFAMVFIYCTLVY
                     WIENLLIPQIGTFDLTYILIVLLISSIIYGVYMPIQYKLGYETTKFFFVMIIMASSFV
                     LPLTIAHSNFEIPFIYQYPSMIVNIVLFLLSLIILLASMFISIKIFSNKELV"
     gene            complement(6416..7273)
                     /locus_tag="OE968_002924"
     CDS             complement(6416..7273)
                     /locus_tag="OE968_002924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCP7220185.1"
                     /translation="MENILEVYNLNKTYTDFSLSNISFALPEDCITGFIGVNGAGKTT
                     TIRSILDVVKRDSGKIKIFGKDFDGNEKELKNRIGVVFDDSYFYEELSMAEMKSIIAP
                     SYDNWCEEDYQQNMKRFNLNPKQKIDTLSKGMKMKFALALALSHKAEFLIMDEPTSGL
                     DPLIRSQILDILTGYMKKCGRGVFFSTHITSDLDKIADMIVMIDNGRIILEREKDTLL
                     DEHRKVKGDIQFLNDETKKLFLNLEITGYGFIGITSKINEVQKNMPDILIERPTIEDI
                     MLAYIERRE"
     gene            complement(7275..7649)
                     /locus_tag="OE968_002925"
     CDS             complement(7275..7649)
                     /locus_tag="OE968_002925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCP7220186.1"
                     /translation="MKVLISNTSDKPLYQQIKEQIKEAIFTEELKEGDAMPSIRNFAN
                     DLKVSILTIRRVYEELENEGFLTRQVGIGTFISTGNLEILRDSKRRIVEQKMADMIKD
                     AKALGITQIELQEMMDILYEED"
     gene            complement(8798..9988)
                     /locus_tag="OE968_002926"
     CDS             complement(8798..9988)
                     /locus_tag="OE968_002926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HCP7220187.1"
                     /translation="MSDMLLWFSVVLVLFAIGDLIASKTKAKVSAVFVTLLLFLILFV
                     TKAIPADIIEKAGMTAAASWSVPMIMFSMGTMLNVKQFIDEWRTVLTAWLGIVAVIVC
                     VSLCIPLFGKSTVLTSIPVINGALPATTIMTQAALEKGLTLAAATATVVFAIQKFIGT
                     PIASRAALQEANRLLVEYHEAKSKGIDLANVDTDKKEAENTGTKVKQAFCEKYDKYYS
                     TNVCIFFIALFSYLGYELSEIIHVNYSIVCLVVGVIVTRIGIVPKDILEKGKIKGFIN
                     MVVFAAVIPSLAKVSLTDLISLFVPIVGMFAASIIGIFLMMKVLPGWKIIGSKPLAFG
                     VGFCQMLGFPTTYLISNEVCNAVGETEEERAYLMSKIMPKLVVGGMACMISIVVAGLM
                     VPML"
     gene            complement(10004..11959)
                     /locus_tag="OE968_002927"
     CDS             complement(10004..11959)
                     /locus_tag="OE968_002927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S9 family peptidase"
                     /protein_id="HCP7220188.1"
                     /translation="MEKIKIENSDIFEYIFPHDISCSPDGKHIAYIISNINEEKDCYE
                     HDLYVMDIKTEKQIHMTQTKDVTSFSWISNTELLFTSKRNKPKSGTTDFYTISIEGGE
                     AKKAFSIPKACSVPVSLGNKLWLLTTKNPTDSKKSEPDRAVEGVDYWTFTDKPFIRDG
                     ENFSQRRRVTLELYQEGENITKAITPKFCEVAGVDVSSDKNRILYTGQIYEDCATPFS
                     GLWEYHIDSGETKELVPQGKYQISLAKYIGKDKVMLQASTLDRSITQNHDIFILDLST
                     NEINMIASPDGMYATLLDVDAVYGGGRSNKVIGDKFIGARICRTMTEFNEFDTKTGNI
                     RIITKVDAFTSFDIYDNTMYTVMLKDYELAEIYSIDMTTGTMKKMTAFSKPYLDTHKV
                     SLPEKLTFVAKNKEEVDGFVIPPIDAKEGEKYPAVLFIHGGPKWAYGYMFTHLKQCVT
                     SKGMYVIYCNPHGGDGYGEKFLEMVERWGYVDYEHLMEFVDTCIEKYPGIDADRLGVA
                     GGSYGGYMTNWIIGHTDRFKAAVSQRGISNLITASLIIDFGDRIMKQTCGDKTPWNHE
                     EVLWNHSPIKYVKNVKTPTLFLHSDRDYRCFMGDTFQMFTALKQLGVDTEMYLFHGDT
                     HGLSRNGRPSNRIARANAIVDWFERYL"
     gene            complement(11976..14042)
                     /locus_tag="OE968_002928"
     CDS             complement(11976..14042)
                     /locus_tag="OE968_002928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S9 family peptidase"
                     /protein_id="HCP7220189.1"
                     /translation="MKEVVESLKKITKERIENTMKKLFTSETFLEYQFISDCQISPDG
                     GYTAFIVKKADIKENGYTSQVYILNNKTGELKQITSINSVGAYAWEDENTILFPALRN
                     EKVKEAVKNGKQCMSYYALSLNGGEAEELFRLPIKGGKLNPIGKGLYAVIDSYDNDRP
                     IVEGLPEEEQQKKINAYNKRHYEHFKEIPYAVNGEGYISRKRKRLYVYDSNINELKAI
                     TAPMFNVVGMKISDGKILYIGQEFKDVKGLKNGVYVFDTNTNTNVCILEKDKYIIKGF
                     ELYQNQVILNLTDALSYGNGENGDFYTIDIDTKEMKLLSGHQHHCIGNTVTSDVKMGA
                     GQTTKVDGEYIYYTSTVDMDCIIERIHIPTGKQEKVTQTGSVDFIDVKDGNIVCVGCL
                     GNGLPEVYTVENGTLCKKTHLNDHILEEYKISVPEYIESKGSSKWEIQGYVYKPVDYE
                     VGKKYPAVLAIHGGPRLTYGPYFMHEIQVFTSAGYFVFFCNPRGSEGRGNAFADIRKQ
                     FGDIDYIDFMEFTDTVLEKYTDIDKTKLAVEGGSYGGFMTNWIIGHTNRFAVACAQRS
                     IANWSGMEGTTDIGYYFCKGQTGASHMENHELQWKQSPLAYADKCVTPTLFLHGEKDY
                     RCYMQEAFQMFSALKIHGCPTKLCLFEGENHELSRSGRPKQKLQRLVEMLDWFSVYIK
                     KDNIGQ"
     gene            complement(14369..15019)
                     /locus_tag="OE968_002929"
     CDS             complement(14369..15019)
                     /locus_tag="OE968_002929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCP7220190.1"
                     /translation="MKVKSNLDEILYHKIIESLIRGEYSVGQKILLNDLCEKFEVSRT
                     PVVQAVKMLNKDGVLTIMTNGKVYVPEYEYDMVKQVCETRTLIETYALEKMMQEEEEV
                     FQQKLDVIKRYSDKCEEYYRQEKSVELALADLELHKAIVEGANNEILNDVYVGIQGRF
                     IVVNYLIRPLKNRNYEGTVQDHFEILKFIEDRDTKKAVDKLRNHIQGTIKRFCEDE"
BASE COUNT         5414 a         2775 c         1753 g         5793 t
ORIGIN      
        1 aattgaagtt agtaaatata aatgcgttta cttttaagta ttgcttaagg gaataaaaaa
       61 taaaaataaa ctctgcaacc atctaaaaat agttgcagag cttacaaaac caaaattatc
      121 taaattgtaa taaaaataat aacatttata cataagcttc ttcccaattt actacccagt
      181 tttctaacga ctttatcttt tcctctgtta gctcctcttc gtgaaatgat actaataaat
      241 tccttataaa attattcttc aaaagatttt gcacatttct tgatataaac tctaaatatg
      301 ccttttcttt gattgcaact gtataataca tacacttgcc tgtttcttga acatataaga
      361 atcttttctt tgatagtttt gataaagttt ttaaagctac tttttctggt aaattatgtt
      421 cttctttcat ataatcaata atctcatatg aattggtttt tatatctaaa ttccaaataa
      481 atttcataat aactaactct aattttgata atttttttaa acacatagtt atcactccgc
      541 ttctttatct atataattaa atattacaat aataatttca caaaatcaat tctaataatc
      601 ataacatacc ttaaaatctg ttcttaactt ctaccttctt aatctcccaa atgatttttt
      661 tatattgtat tcaatagtat aatccttttc caaaatataa cttaccagtt aaaataatct
      721 ttatttttac ttattctcgc cttttacaga agttaataat tttttataag ttacatcaat
      781 tccaaaagct ccaagaggtg cagttataag tatagctaga actgctaacg tcaaaataag
      841 ttgtccagat gccatcccca ttgcaagtgg tacacctcct attgccgcct gtactgtagc
      901 ctttggaata tagccaatca tacagaacaa tctttccttt attgtcaaat ttgtcttaat
      961 aaggcagaag aatactccta ccatacggaa taaaagaact ccaaatatta aaattacagc
     1021 tccaattcct gctttaaatg cataacttat atctactgtt gcccctacca aaacaaacaa
     1081 gagaatttca gcaccaaccc atagtttcga atactttata gacaatcttc ttgcaactac
     1141 acgatatttt atctgaagga aaatcccaat actcataact gctaataatc cagaaaatgg
     1201 cacaataccc tctaaagcag tctctaaact tatcattaaa aatgagatac ttaaaagcaa
     1261 caccccttta gcagaatctc tcatatgaac cttcttaaaa aatactgcta aatagattcc
     1321 aatcactgct ccaactatta cacctaatat aattgatact ggaatttgta aaaagctaat
     1381 agctgatata ctatttcctt gtgccaatcc tgtgaatact gtaaacatca caattacgaa
     1441 aatatcgtct atagaagttc ctgctaaaag catctgtgga atactttttt ctgtaccata
     1501 accttcttcc attaatttaa gcattttagg tacaataatt gcgggagaaa ctgctcctac
     1561 tactgcaccc atgactgctg cttccaatat agaaacgcct agtaactttg gtgctaaaac
     1621 tatcattccg ataatttcaa aagtagctgg aataaagcac ataagtacag cgggtcttcc
     1681 cactttcttc aaatcgttta tatctaaaga taatccagcc cttgttaata taataatcaa
     1741 tgcaatcttt ctaaggtcag aagaaatatc tagtattgaa ttatcaatca aatttaaaac
     1801 atatggacct aatataattc ccgtaagtaa cattcccaat aagttaggta attttatcct
     1861 cttaaaaata cctcccgagg ccattcctaa taaaaaaatc aaagctaaac ttgtcaacat
     1921 attcctaccc tatcctttct ctaatattct ttctcttcta atcatacatt atgttgtttt
     1981 atttattgtt ttgttgaaat tttttgtagt gaataaatag atttatccat attaaatata
     2041 tatgaaatag cgcatactac aaagaaataa ggtaaatagc tgtacccaaa aacttctgcc
     2101 cctataaata caggtgcaaa aaaagtattt gtagcactac caaagacact agcatagcca
     2161 agcgctgcaa ctaattcaat tggcaaatta aaaaatcctg ctaacaatac accaagacta
     2221 gctccaatgg aaaacaaagg tgtaacctct cctccttgaa aacctgctga caaagtcagt
     2281 attgtaagta taaactttaa cagccagtca aatgaataaa tttctccacc atagaaacta
     2341 ttttgaatta aatttgtccc taaacctgaa tatcttcctt tataaaataa aaggaataat
     2401 acactaagac atactccaat aatagcaatc cttatcatag gattttttaa tctattccct
     2461 atttttcttt ttgacaattt cagacaccat gcaaatgctc caccaaccat tccaaaaata
     2521 attcctaaaa caataagctt ccaaaatatt gacaagtcaa atacaacttt agaagaaagt
     2581 gcaaaagaaa atttctctaa ccctaaagct tttgatactg cacttgctgt aaaagaagca
     2641 gtaaacgcag gaaaaagcga ttgatactcc agtgaaccag caaccaaaac ctccatagca
     2701 aatagtattg ctgctattgg tgtctcaaat aatcctgcaa aaccagctgc cataccagtt
     2761 actagaaaaa tactagaagc attttttata ggcaaccttt tacctaccca atgtgaaaaa
     2821 gttgcaccaa tctgaacagc aactccttct cgtcctgcac taccaccaaa taaatgggtt
     2881 aaccatgtac ctgatattat aaatggaacc aatcttaaag gaataatttc ttcttctcca
     2941 tgccctacct caaatattag attcattcct ttactacttt ttcctccaaa tttaaaatag
     3001 caataagcaa taacaactcc tactactgct aaaaatggta tcagatacat tggatatgtt
     3061 tctcgaatat ctgtaacttt tagaagaacc gttccaaata tggtatctat aagacctata
     3121 attgcaccaa ctggtatacc tatgagtcct aaaaaaaata gtccaccata tgttttataa
     3181 acgcttttaa ttcttattat cattttaatc catattaaag ttttaaattt ttctatcatt
     3241 ttaattcctt tctatttgca tcataagatt ttttgaaagt tttattacat caactgtagt
     3301 caatgtaatg actatcataa ttgtttttta aattgatagg atataggtac actcttaacc
     3361 cattcttaat aaaataatta acatataatc tactattttt tctattaatt aaatatttct
     3421 tcaaatttaa aaaataaaaa tttagtaagt acttcacctc cattttatcg atttaaacaa
     3481 caaaaaaagc tggtggcatc tatgatatca tagaagtcat cagctcattg gcagtttagg
     3541 atattatcat ccaagggaga acctcattcc cataattatt atataatttt ttatttttca
     3601 tatgtctatt ttatgtaaat tgtattttta atgttataaa taatataacc tatcaattaa
     3661 aatattaaag tctctaatat tatgagtgtt caatacttca tattattttt atgatatata
     3721 atttaaatga ttttctttac tttgcattat gatacatgat ttaaatattt ttcttcactt
     3781 tgtatactaa agtttattta aaatattttc tttcctatta tactatgctg ttaaatattt
     3841 ttcaactgaa gtattgtaga actttaaaat tactataaaa aattatattc taaaatactt
     3901 gtaatactac atatcaccct taacacttaa gtataatttt aaagcaaaat tcttattact
     3961 tatatttaat tttgattcta catctttaga tataatttta agtaatttaa gaaattattg
     4021 taaatcatat agtactactc aataattagg tttttcaatg ttccaattat gtttctttga
     4081 tataatccac catgactaaa aactatcgtt tctatatcat aattacttat atttttaata
     4141 gcatctttta actcttgttt gttgctgtac atcacatcaa caggcttaag ttctccattt
     4201 tctacctgta acaaatctcc agcaataagt actttagact cttttaaata aagacatatg
     4261 tgacctctag tgtgacctcc tgtatgtata acttctattt cctcacctag attcaatttt
     4321 tcatggttat ctaatgacac atctacttta gtatatgatg atttaaatcc aagtcccata
     4381 acatttagca tactaagcat cttatcatca attttatcta ccatttgttc caacatataa
     4441 agtttaaaag gagtttcttc tcctgttata tagctgattt cacttttgta tgcatatact
     4501 ttgatattat tcttagattt ttctcttaga taatttatgt ttcctatatg gtctatatca
     4561 tgatgagtga ttattatatt ttttaactta tcaaagctcg tgttactttt attaagagca
     4621 tcaattatta aatcaccttg acccggaaga cctgtgtcaa taagtgttgc atcatcttct
     4681 gtgtagatta caggaatata cataacttta tcttcaccga atacatttga tgaaattttt
     4741 aaaacatcta atccctttgc taaattcata atttttctcc ttataattac ttaattagag
     4801 gtcaatttaa ttaaagaaat tgagaaaatg tagattttcc tctagttata ttttattaat
     4861 taaaaattat taatacctag tatatcattt aagttgaagg attactcgac ttgatttttt
     4921 tgttatttta tggtatagta attaatatag aagtaagtaa ttgcaagctt tgcaattact
     4981 tttatttttt tctaataact attttatttt tgataattcg tataaaatta aaagtaaagt
     5041 aatatagaaa atatgaatat agaaaaactt taataagaaa ataaattatg aataaataaa
     5101 agaaacgcaa tactgtatat agatgattat ttagaaaaat aaaatctctt ttaataaaaa
     5161 taagcttcaa aataaacttt tagttcataa agcttaggag taactaaatt gagtgcaagt
     5221 gtatctactg ttcaaaataa atagttcata aagcactctt ttttatatta aatcaattat
     5281 attttcgtca tttcagcaat gaaaaagaag cttatctcta ttttgagaca gcttcttttt
     5341 attaacgtcc tactttttat tagttttcta aaattaaaaa gctttattta taggattcct
     5401 tagatttata ttttgacgat ataatttttt aaaaacacct taaaagatgg tatacaatac
     5461 acacaatcat actcataatt gaaaaataat caatggaaaa caaaattact ggatattccc
     5521 tattaaaaaa tacaaattga ttcacaagaa acatataatc tataatatta tgatgttact
     5581 ctcccacacc aagtaacttt attttcaagt aaccttttca taccatctaa cttcactcaa
     5641 taaaaatggc aatataaata tatactctat tttttacttt taaatatctg acaagcttta
     5701 tatactattg gaagtaagat acaaagtaaa acagcccaat ctggtaaatg tggcatataa
     5761 aagtccccct taccttatac aagctcctta ttactaaaaa ttttaataga aataaacatt
     5821 gaagctaaca gtataattaa acttaaaagg aacaatacaa tattcactat catggatgga
     5881 tactgatata taaatggaat ttcaaaattg ctgtgagcta tagttaatgg taatacaaat
     5941 gatgaagcca tgattatcat cacgaaaaag aattttgttg tttcatatcc taatttgtat
     6001 tgaataggca tataaactcc ataaataata gaacttatta ataaaacaat caaaatatat
     6061 gtcaagtcaa aagttcctat ttgtggaata agtaaatttt caatccagta aactaatgta
     6121 caatagataa ataccattgc aaataaaaca tacttagatt gaactaagcc acgtctagga
     6181 taaggagttg aacaaagtaa tacagatgct tttgaatatt gactctcctt taataataga
     6241 tactgacaca gcataaattc tgaaaatata attgatagta caaatcccaa tatttgtgca
     6301 aatggaggta aacgccataa tataaataat gggattccta ttgcaataaa taatatcaac
     6361 aatacatatt tttttacaat cagaatatct tttttaacta aatgaatcaa cataattact
     6421 ctctcctttc aatatatgca agcataatat cttcaattgt aggacgctct attaaaatat
     6481 ctggcatatt tttttgcact tcattaattt ttgaggtaat ccctataaaa ccataacctg
     6541 taatttctaa atttaaaaat aattttttgg tttcatcatt tagaaattga atatcccctt
     6601 ttacttttct atgttcgtcc aatagagtat ctttttcacg ctctaatata atacgtccat
     6661 tgtcaatcat aacaatcata tctgctattt tgtctaaatc agatgttata tgagtggaaa
     6721 agaaaacacc acgaccacat ttcttcatat atcctgttag tatgtcaagt atctgactac
     6781 ggattagtgg gtctaaacca cttgtaggct catccataat taaaaactca gctttatgcg
     6841 ataatgctaa tgctaaagca aatttcattt tcattccttt tgaaagtgta tcaatctttt
     6901 gttttgggtt aagattaaaa cgcttcatat tttgttgata atcttcttca caccaattat
     6961 catatgaagg tgcaataata cttttcattt ctgccattga caactcctca tagaaatatg
     7021 aatcatcaaa gacaactcca attcgatttt ttaattcctt ctcatttcca tcgaaatctt
     7081 taccaaagat ttttattttt ccactatcac gctttacgac atccaatatc gaacggattg
     7141 ttgttgtttt tcctgctcca ttaacaccta taaatccggt tatacaatct tctggtaatg
     7201 caaagcttat attagataat gaaaaatcgg tataagtctt atttaagtta taaacttcta
     7261 aaatattttc catattaatc ctcctcatat agaatatcca tcatttcttg taactctatc
     7321 tgtgtaattc ctagtgcttt tgcatcttta atcatatctg ccattttttg ttcaactata
     7381 cgtctctttg agtctcttag tatttctaaa tttccagttg aaataaatgt tcctattcca
     7441 acttggcgtg taagaaagcc ttcattttca agttcttcat acactcgtct aatagtcaaa
     7501 atactaactt ttaaatcatt agcaaaattt cttatggatg gcattgcatc cccttctttc
     7561 agttcttcag taaatattgc ttctttaatt tgctctttaa tttgttggta taatggctta
     7621 tctgatgtgt tagaaatgag cactttcatt ttttatcacc ccctttttat cactttcagt
     7681 gtgatgttat catatacaca ctatacactt agagcacttt tttgtcaata taaaagatgt
     7741 aaaatattac tatgacaaaa taaatatgaa tgaaatatta gagattgtta atagccataa
     7801 acacttttta aaactacata agataggatg tattaaatat ttattaaaag taagaattga
     7861 atatataaaa gaaaaagtaa tcctgtatga atgatttgtt taatgataaa ttaagttata
     7921 aactatttat aaaaaacata aaggaataaa tccatttcta attacaaaca tactaaaaaa
     7981 tttagataat aataaataaa tagtaataaa tgggatgaat ttataagaat ttggatagag
     8041 gaaagagtta ttcaagagtg tagactagag gtaaactcta tattaaaaaa atttaaattg
     8101 ggatattatt atgtatggaa tatttgcaga agtaaccttg ctataagtat agaagatttt
     8161 tttgattaca aaagataata ctctaaaatg tgaggatttc aacattcaat actgtgcttt
     8221 aaataatatc actccaaaat accatccacc ttttactata attgaatacc ctaattattt
     8281 taaaaaagaa aacattagaa acggaaaacc ttgtatatat aaaataaaaa atactaactt
     8341 ctaaaacacg aatactcttt gataaataaa acaaaaaata attttaataa ttaaaattgg
     8401 ctatctcaaa ctagagataa gtctctttct cacttttaaa acgttgaaaa tatattcgat
     8461 ttcgtacaaa aaagagtgcc ttagaactaa aaagttcact ttgtggcact cccttttttc
     8521 tcctcttttt aattttttat aaaaattctt caaaaatatt attaaatacc ctatattata
     8581 cataaatcaa attaaagttg cattttagca aataaaaaca aattataact attagcatag
     8641 caaataaaaa atctgctatc ttataaaatc aaaattataa ttataaaaag aaaatattct
     8701 tataacaaat taactaatat aaaattattt tataaattaa tactactttt tagcttctcc
     8761 tataaattaa taccactttt ttaactatga aacctatcta caacattggt accataagac
     8821 cagctaccac aatagaaatc atacaagcca taccaccaac taccagctta ggcataatct
     8881 tagacatcaa atatgctctt tcttcttccg tttctccaac agcattacac acttcatttg
     8941 aaattaaata tgtagttggg aatcccaaca tctgacaaaa ccctactcca aaagcaagag
     9001 gtttagaacc gataattttc caacctggta acaccttcat cataaggaat ataccaatga
     9061 tagaagctgc aaacataccc acaattggta caaaaagact aattaaatct gtcaaagaaa
     9121 cttttgctaa agaaggaata acagctgcaa acacaaccat gttgataaat cccttgattt
     9181 ttcctttttc caaaatgtct tttggcacaa taccaatacg tgttacaata acaccaacaa
     9241 caagacatac aatagaataa tttacatgaa taatctctga aagttcatac cctagataag
     9301 agaataatgc tataaaaaat atacaaacat ttgtagaata atatttatcg tatttttcac
     9361 agaaagcttg ttttactttt gtgcctgtat tctctgcttc tttcttatca gtatcaacat
     9421 ttgctaaatc aatgcctttt gattttgctt catgatattc tactaaaaga cggtttgcct
     9481 cttgtaacgc tgctcttgaa gctattggtg taccaataaa cttctgaatt gcaaatacaa
     9541 ctgttgctgt agctgctgca agtgtcagtc ctttttctag tgctgcttgt gtcataatag
     9601 tagtagcagg taaagctcca tttataactg gtatgcttgt caatactgtt gattttccaa
     9661 acaaaggaat acataatgag acacagacta taactgctac aattccaagc catgctgtca
     9721 atactgttct ccattcgtct ataaattgtt taacattcaa cattgttccc atactaaaca
     9781 taatcattgg aacactccaa ctagctgctg cggtcatacc tgctttttca ataatatcag
     9841 ctggtattgc ttttgtgaca aatagaatca aaaataaaag tagtgtaaca aatacagctg
     9901 atacttttgc ttttgttttg cttgcaatta aatccccaat agcaaataaa actaatacga
     9961 cactaaacca taataacata tcactcatag aataaccccc ttattataaa tatctttcaa
    10021 accaatctac aatagcattt gctcttgcaa ttctattaga tggtcttcca tttctagaca
    10081 atccatgtgt atctccatga aacaaataca tttctgtatc tacaccaagc tgttttaatg
    10141 ctgtaaacat ttggaaagta tcccccataa aacatctata atccctatca ctatgtaaga
    10201 acaatgttgg tgtcttaaca tttttcacat atttaatagg tgaatgattc caaagaacct
    10261 cctcatgatt ccaaggcgtc ttatctccac aagtctgctt cataattcta tccccaaagt
    10321 caataattaa agaagctgta atcaagttac taatacctct ttgagaaact gctgctttga
    10381 aacggtctgt atgaccaatt atccagtttg tcatataacc accgtaactt ccccctgcaa
    10441 cccctaagcg gtctgcatca atcccaggat atttttcaat acaagtatct acaaattcca
    10501 taagatgctc atagtcaaca tacccccatc tttctaccat ttctaagaat ttttcaccat
    10561 aaccgtcacc accatgaggg ttacaataaa tcacatacat tccctttgat gttacacact
    10621 gcttcaagtg tgtaaacata tagccatatg cccatttagg cccaccatga atgaacaata
    10681 cagcaggata tttttcgcct tctttagcat ctataggtgg tataacaaaa ccatcaactt
    10741 cttctttatt ttttgctaca aacgtcaatt tttcaggtaa tgaaacctta tgagtatcta
    10801 aatatggttt agaaaaagca gtcatttttt tcattgtacc tgtagtcata tcaatgctat
    10861 atatttctgc taactcataa tctttcaaca ttactgtgta catggtgttg tcgtaaatat
    10921 caaaagatgt aaaagcatct acttttgtga tgatacgtat attacctgtc tttgtatcaa
    10981 actcattaaa ttctgtcata gttctgcaaa ttcttgcacc aataaatttg tctcctataa
    11041 ctttattact acgtccacca ccatatactg catctacatc cagcaatgta gcatacatac
    11101 catctggact agcaatcata tttatttcat tagtactcaa atcaagtata aaaatatcat
    11161 gattctgtgt gatagaacgg tctaatgttg aagcttgcaa cattacttta tctttgccaa
    11221 tatattttgc caaacttatt tggtactttc cttgtggtac aagttctttg gtttcaccac
    11281 tgtctatatg atactcccaa agtccagaaa aaggagttgc acaatcttca taaatctgac
    11341 cagtatataa aattctgttt ttatcagaag aaacgtctac acctgctact tcacaaaatt
    11401 ttggtgtaat ggcttttgtt atattttcac cttcttgata taattctaat gttacacgtc
    11461 ttctttgaga aaaattttct ccatctctta taaaaggttt atctgtaaat gtccaataat
    11521 ctacaccctc tactgcccta tctggttctg attttttaga atccgttgga ttttttgttg
    11581 tcagtaacca caatttattt ccaagtgata caggtacgct acaagctttt ggaatagaaa
    11641 atgctttttt tgcttctcct ccttctatag aaatagtgta aaaatctgtt gtacctgatt
    11701 ttggcttatt tcttttagat gtaaaaagga gttctgtatt agaaatccaa ctaaatgatg
    11761 ttacatcttt tgtttgagtc atatgtattt gtttttctgt tttgatgtcc atcacatata
    11821 agtcatgttc atagcagtct ttttcctcgt tgatatttga tataatataa gcaatatgct
    11881 ttccatcagg tgaacaagaa atatcatgag ggaatatata ttcaaaaata tctgaatttt
    11941 caatctttat tttttccatt tttatattct cctttctact gtcctatgtt atcttttttt
    12001 atatatactg aaaaccaatc tagcatttca actaatcttt gtagcttttg ttttggtcta
    12061 ccagaacgag acagttcatg gttttctcct tcaaatagac aaagttttgt aggacaccca
    12121 tgaattttca atgctgaaaa catctggaat gcttcttgca tatagcatct atagtctttt
    12181 tcaccatgta aaaataaagt cggtgtaaca catttatcag cataagcaag aggtgactgt
    12241 ttccattgaa gctcgtggtt ttccatatga gaagcacctg tttgtccttt gcagaaataa
    12301 taaccaatgt ctgttgtacc ctccatgcca ctccagtttg caatagaacg ctgagcacaa
    12361 gcaacagcaa aacggtttgt atgaccaatt atccaattcg tcataaatcc accataactt
    12421 ccaccttcaa cagccaattt tgttttatca atgtctgtat atttttcaag tacagtatct
    12481 gtaaattcca taaaatctat ataatcaata tctccaaact gtttcctaat atctgcaaaa
    12541 gcattgccac gaccttcaga cccccttggg ttacagaaga atacaaagta acctgcactt
    12601 gtaaatacct gtatctcatg cataaaatat ggtccatatg tcaatcttgg tcctccatga
    12661 atcgccaata cagctggata ttttttcccc acctcataat ctactggttt atatacgtat
    12721 ccttgtattt cccatttaga acttcctttt gactctatgt attctggcac agaaatttta
    12781 tattcctcta aaatatggtc atttaaatgt gttttcttac acaatgttcc attctctact
    12841 gtataaactt ctggtaatcc atttcctaaa caacccacac atacaatatt gccatctttt
    12901 acatctataa aatcaactga acctgtctgt gttacttttt cctgttttcc tgttggaata
    12961 tgtattcttt caataatgca gtccatatct actgtagaag tgtaataaat atattctcca
    13021 tctacctttg ttgtctgacc agcacccatt ttaacatcag atgttactgt atttccaata
    13081 caatgatgtt gatgccctga aagaagtttc atttctttcg tatcaatatc aatagtataa
    13141 aaatctccat tttctccatt tccataagat aaagcatcag ttaggtttag tatcacttga
    13201 ttttgatata attcaaaacc ttttataata tacttatctt tttctaatat acagacattt
    13261 gtgtttgtgt ttgtatcaaa tacatagacc ccatttttca aaccttttac atctttaaac
    13321 tcttgcccta tatataagat ttttccatca cttattttca tacctacaac attaaacata
    13381 ggtgctgtaa ttgccttcaa ctcatttata ttactgtcgt atacatatag gcgttttctt
    13441 tttctgctaa tatatccctc cccattgaca gcataaggaa tttctttgaa atgttcataa
    13501 tgtcttttgt tataagcatt tatttttttc tgttgttctt cttctggcaa tccctctaca
    13561 ataggtcggt cattgtcata agaatcaata actgcataca aaccttttcc tataggattc
    13621 aatttaccac ctttgatagg gagtctaaaa agttcttctg cttctccacc atttaaagat
    13681 aaagcatagt aactcatgca ttgcttaccg tttttgacag cttcttttac tttttcattt
    13741 cgcaaagcag ggaacaagat agtattttca tcttcccagg catatgctcc aacagagttt
    13801 atagacgtta tttgttttaa ttcgccagtt ttattgttta atatataaac ttggcttgtg
    13861 taaccattct ctttgatatc agcttttttt acaataaatg ctgtatatcc tccatctggt
    13921 gatatttggc aatcacttat aaattgatat tccaaaaatg tttcactcgt aaatagcttt
    13981 ttcatagtat tttctatcct ttctttagta atttttttca aactctctac cacctctttc
    14041 attttttatt ttaaatttaa aataaaaaat tttaaattta aaataaaaaa ttttataaag
    14101 gttatttttt taggaagcct tctggcttcc ttgtaatatt tgtaatttaa agtatattta
    14161 atccatgctt aattcatgct taattcatac ttaatctata cttaatctat acttaatcta
    14221 tatttaattc atacttagac ttatttacac tatatttaga ttatatttat tagattatat
    14281 ttagattatg tttaaactat aattagatta tacttagact acatttagca acttaataga
    14341 taagtatata tagtaacttc aaaacttatt attcatcttc acagaatctt ttaatagttc
    14401 cttgaatatg atttcttagt ttatctactg ctttttttgt atctctgtct tcaatgaatt
    14461 ttaatatttc aaaatggtct tgtactgttc cttcataatt acgatttttt aatggtcgaa
    14521 ttaaatagtt cactactata aatcttcctt gtataccaac atatacatca tttaaaatct
    14581 cattatttgc cccttctaca atggctttat gtaattccaa atctgctagt gcaagttcta
    14641 cagatttttc ttgacgatag tactcctcgc atttatcaga gtatcttttt attacatcta
    14701 gcttttgttg aaaaacctct tcctcttctt gcatcatttt ttctaaagca tatgtttcaa
    14761 tcagtgttct cgtttcacaa acttgtttta ccatatcata ttcatactct ggtacgtaca
    14821 ctttaccatt tgtcataata gtaagcactc catctttatt tagcattttt actgcttgta
    14881 caactggtgt tctgcttact tcaaattttt cacaaaggtc atttagtaat attttttgac
    14941 ctacagagta ttcaccacga ataagacttt caataatctt atgatataaa atttcatcta
    15001 aatttgactt tactttcact actctcacct tatttctatt cttttgccat attatattga
    15061 attactggac tttaattact tttagtaata tttttaaagt agaaattctt atttgatagt
    15121 acttttgtac tacaatttaa attattgtac tgtaaatcat gctcttatac tatagattaa
    15181 ttcattgtat tgcaaatcaa gttattgtac tatagattaa atcgttgtac ttcaaattaa
    15241 actattatac tatagattaa accattgtac ttcaaattaa actattatac tatagattaa
    15301 atcgttgtac ttcaaattaa actattatac tatagattaa ttcattgtac ttcaaattaa
    15361 actattatac catagattaa ttcattgtat tgcaaatcaa gttattgtac tatagattaa
    15421 atcgttatac ttcaaatcaa gttattgtac tatagattaa atcgttgtac ttcaaattaa
    15481 actattatac tatagattaa atcgttgtac ttcaaatcat gctagtgtac tatagattaa
    15541 atcgttgtac ttcaaatcat gctagtgtac tatagattaa atcgttgtac tttaaattaa
    15601 actattatac tatagattaa ttcattgttc tgcaaatcat gctagtgtac tacaaattaa
    15661 actataaatg tttactatct cttaataatt tgaataatat gttacaaaaa gtatagcacc
    15721 tttttatttt tttcg
//
LOCUS       DAJMZY010000097        15590 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.098, whole genome shotgun sequence.
ACCESSION   DAJMZY010000097 DAJMZY010000000
VERSION     DAJMZY010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15590)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15590)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15590
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.098"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            284..1675
                     /locus_tag="OE968_002930"
     CDS             284..1675
                     /locus_tag="OE968_002930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HCP7220191.1"
                     /translation="MSSTESVSKKSGHPKSFWLICMTILWERFSYYGLTALLVLFFTA
                     SVAQGGLGLSTQEATSMFGLFTGLIYLTPLVGGWLADKVLGQQKCISIGALLIAIGDF
                     VLFASSTSIAMVWVGLSIIILGNGFFKSSCSNIVGDIYPKTDVSRKDAAYSLFYMAVN
                     VGAFIAPIICGLLSDNVFAVRGASGDIVSYGYKMAFLICGIGMMLGMIIFTLLAPKLL
                     NEVGKYPVTKGNKGEKIEYGPLTKLEKNRIIAMVILFLFVVLFWTAYYQTQSSFMIYV
                     RDNVNRTLFGFEMPVAWLTSLNAILCVALCPVLATLWVKLSHTKRGDFSIPVKMGLGM
                     IIMGVGFIVMVFATLANGPDGMVKASILFIVLTYIFTTVGELFLSPIGLAMFNKLAPA
                     KYATLSMGAWYLTSFFASLLSGKIAGFTATLGFLQIFGGIATVLIIFGLILLGIRNVL
                     TRLMAMDLLTKEK"
     gene            1928..3721
                     /locus_tag="OE968_002931"
     CDS             1928..3721
                     /locus_tag="OE968_002931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HCP7220192.1"
                     /translation="MNIKDRLSGLRKFMEEKNIDAYMIPSSDNHQSEYVGDYFKSREF
                     ISGFNGSAGTVIVTKDEAGLWTDGRYFIQAESQLEGSTIKLFKMGQEGCPTTDEYLYK
                     NIPEGGTLGFDGRVISAREGATLAEKLSKKGIKIEYQYDLIDSIWPDRPALSDSKAFL
                     LDVKYCGESFSSKLARLREKMSEKGTSTHVITTLDDIAWLFNIRGGDVKYNPVVLSYA
                     VITLKEVYLFVDESKLNEEILNELAKENVQIKPYNDVYEFVKNIDKTEKVLLDGTKLS
                     YTIYNNIPCEVEKVDEFNPVMFFKAQKNEVELENIRNSHVKDGVAFTKFMYWLKKNVG
                     KMEITEISATQKLEDLRREQEGFFEPSFNTIAAYKEHAAMMHYSATPESNYKLEAEGL
                     FLVDSGGQYYDGTTDITRTTVLGPISDELKLHFTSVARGMINLSKAKFLHGCRGYNLD
                     ILSRSCMWNMGIDYQCGTGHGIGFVLNVHEAPNGFRWRVVPERFDSAVLEEGMVTTNE
                     PGIYIEGSHGIRTENEIVVRKAEKNFYGQFMEFEVVTLAPIDLDGIVPELMNKDEKDY
                     LNWYHKLVYDKISPFLTDEEREWLKVYTRAI"
     gene            complement(3802..5184)
                     /locus_tag="OE968_002932"
     CDS             complement(3802..5184)
                     /locus_tag="OE968_002932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HCP7220193.1"
                     /translation="MSVLKTQEKLKQPRDLYFCCSIFTFVGLAYYGMKLVLLLFLAEQ
                     VSKGGLGLTPAESASMLASFLAWTYFSPVIGGWVSDRFLGPKNCIILGMLMVSIGYFL
                     GYIANSKMDINIMIFLSGLGIGFYKGNLHTMVGNLYTNDDPRKDGAFSITYMATNLGT
                     LFGPLICGLVANEWFAMKSGLSISMYGYRYVFLFSSITVLIGLFFFIFGNRKFYKPLN
                     NDPSNGRESIRKSLEYKKMLASRPLTLIEKKRIIVILVLAFFTVFFWIAYNQASMSIA
                     LYTKEHINLTVGNFQIPTSWIDSYNGLLCVILGPISALVWVKLSQTKKGDLSVPKKMS
                     LGFILLAIAFLFMIVAVIQTGTDPNSIHKASVFWVVGFLTFQSIGEICFSPVGYGMVN
                     KLSPEKYISFLMGVWFLGKFAANKLSGYTQAIIDQLGMLQVFIVIPSFLLIFGIILLI
                     MNKKLVELSN"
     gene            5442..5789
                     /locus_tag="OE968_002933"
     CDS             5442..5789
                     /locus_tag="OE968_002933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HCP7220194.1"
                     /translation="MIRKKSELQVEVKENLNGGIGKVKLENIIQNEELKGKGRLFKRV
                     ALPVGSSIGVHDHTTDFEVYYILKGKGKVFDNGEFVEVNEGDVVYTADGEKHSIENIG
                     EEDLEFVALVLYM"
     gene            5807..6841
                     /locus_tag="OE968_002934"
     CDS             5807..6841
                     /locus_tag="OE968_002934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220195.1"
                     /translation="MTGKIEEIKDKINRFCNSNLNQEYKDISFKILQNLLDNNKEIIH
                     SSRADIWSSAILNIVLEQNLLYNKKHPLHITKKEFSKQIGVSLNTINNKSSLIKDVCS
                     IDFLNQDTIAISNVEFWVKETNSKSKSVDLDLEKKKILYKRYIKLSQDANSDIESIRY
                     MEEAVNIGKSMITKEDKELGFWKGLSTRAYMIALESLARKLESINNLKESKKVLEYLI
                     EINPSDEQGIRYKLLNVLIRLNDRTSINKLFELYKEEKSATWMYSKALYYFKNKSMFL
                     ANDSIKVARSKNKYVGLYLLDWRNAFGREFVTEEEKAEAVYYYDENIVIWNEVKGSMD
                     WLLKKMLEFS"
     gene            complement(6890..7939)
                     /locus_tag="OE968_002935"
     CDS             complement(6890..7939)
                     /locus_tag="OE968_002935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCP7220196.1"
                     /translation="MEINYKKRNFKSFAKRKNIEISVQRYLIDALSYMALGLFSSLLI
                     GTIFNTLGDNFNISLFTEVISPLAKQVTGPAIAVAIAYGLQAPPLVLFSCALVGACGN
                     ELGGPVGAFVATLFAVEVGKLVSKETKIDILVTPAVTILIGVLVAELIGPAVSAFMTS
                     FGNIIMQATTMQPIIMGALVSALVGIALTLPISSAAICMMLSLGGLAGGAATVGCCCQ
                     MVGFAVMSFRENGVGGLVAQGLGTSMLQVPNIIKNWKIWIPPTVASILLGPLSTTIFK
                     MENIPIGSGMGTCGLVGQFGTVTAMQSAGKGGISMWVGILLLNFILPAIVTLLISEFM
                     RKKGLIKPEDLKLDV"
     gene            8214..9749
                     /locus_tag="OE968_002936"
     CDS             8214..9749
                     /locus_tag="OE968_002936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220197.1"
                     /translation="MIFVKNKKYRKIAIIISIPILLVAQYYLFKFGILRPMVKGVEIE
                     IVDGEYVKDIDKYVVKLNETVTLSTGEYIKVPSYAKNPNIWFNVLDNSGTLKIDGNKM
                     TALKVGYSSVGIMKNSRVLKKATIKVVDPEVESLDMEINGDLKHVGDSATIESTIEVD
                     YDKFKKSYKPVYKSSNENILKIKGNKVSAVGVGKATIYAKCGNKEIERTFRIQARVAE
                     INMDDIKIEVDQNEKLKPDIITSPPGLEPPKIYYELVDSKLPVERAISLSSNGNVVGL
                     REGKDRVRITCGDKSKVITVTVVKETITNDYIQNLVGSHKIVNNKVIIKLEWDYMKDV
                     FDYDIYLKDKLSGESFKKIKSITINESDLGKSNKVYATIEVDMKGNQNIDFDIYVIGK
                     KDSDTTKPSNVINITNGNGNSNNDNNIKDMRVENISANVDRDNNVIRVNWSSISHKDC
                     TYSIYVKNNTNGDGEFTLYQSDIQGNEHTISIPEGDLNLDIYVVANYNGNSSQNSDVI
                     NVR"
     gene            complement(9934..10620)
                     /locus_tag="OE968_002937"
     CDS             complement(9934..10620)
                     /locus_tag="OE968_002937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate/glutamate racemase family protein"
                     /protein_id="HCP7220198.1"
                     /translation="MKTIGLIGGMSWESTITYYQVINTVIKERLGGLHSSKCILYSVD
                     FQEIEECQSSGNWEKSAKILADAAIKLQEAGADFIVICTNTMHKVSDKIQESIHIPLL
                     HIADVTATVLREKEIKKVALLGTKYTMEQDFYKNVIINNGIEVLIPNEEDRIIVNDTI
                     FNELCLGIISESSKKAFLSIIDKLGKQGAEAVILGCTEIGLLIKQNDTSIPLFDTTVI
                     HAIEAALSSI"
     gene            10745..12127
                     /locus_tag="OE968_002938"
     CDS             10745..12127
                     /locus_tag="OE968_002938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HCP7220199.1"
                     /translation="MPINSFENYPMTWKPKLDNRKPPIYKTLAMLLEEDIKRGNLNPG
                     DKLPPQRELADFLDLNLSTITRAFKLCEEKGLICAKVGKGTFISSDVNVSNTLLYQTE
                     SKDIIELGTVHPPYEQNTYIIDFIKNVLKQPEMDRFLQYMSPSGTYMQKKSIAKWIER
                     NNVYTSEENILLSTGGQNAICATLLGLFKAGDRIATDSLSFSGIKSIAKMIGIQLVPI
                     PQENNEISIEYLESYCKNENIKGIYLIPDYHNPTTHTMSDLSRKKIAKIAKQYNIIII
                     EDAINSIFRDGIQTPIFSLASDNTIYIFSTSKFLCAGLRVAFVVAPKRYIENLENALY
                     NMNLMVSPFTAEIVHRLLYSPIIDKIIEEKRDAIIERNEVADKVLSDYNLIGDKNCSF
                     RWLLLPDELDGKSFEISAKNLGVQVYCAERFSVGNSTVPKAVRICVTAPKDVEELEKG
                     LNIIKSLLKS"
     gene            12529..13797
                     /gene="eam"
                     /locus_tag="OE968_002939"
     CDS             12529..13797
                     /gene="eam"
                     /locus_tag="OE968_002939"
                     /EC_number="5.4.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 2,3-aminomutase"
                     /protein_id="HCP7220200.1"
                     /translation="MNEQTRISLERAAELKSKIDDYIQARKTINRGLEKEEEINKRKQ
                     KILSILNGTEEDWNNYKWQLSNRITDVDTLSKIITLTKKEKEYIKEVGTQFRWAISPY
                     YLSLIDPEDICDPIKLLSIPTHIELEDEQEDLDPMGEEYTNPAGCITRRYPDRLIINV
                     TNECAMYCRHCQRRRNIGQQDSHKSKAIIQESIDYIRENEEIRDVLVTGGDALTLKDD
                     YLEWILSQLKEIPHVDYVRLGTRTLVTMPQRITDEFCNMLKKYHPVYINTHFNHPMEI
                     TKESKEACEKLANAGVPLGNQAVLLNGINNDKFVMRCLNQELLKIRVKPYYIFQSKHV
                     KGTKHFNTSVDDGLEIMEYLRGYTSGMAIPTYIVNAPKGGGKTPLLPQYLVSKGTDYV
                     MLRTWEGKVIKMEDEPAVDIKKLIKEQAQD"
     gene            complement(13890..14246)
                     /locus_tag="OE968_002940"
     CDS             complement(13890..14246)
                     /locus_tag="OE968_002940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220201.1"
                     /translation="MKKALISLLVLSCLLLTAPVNESSYADSQKNVPVSQNTKLTQEQ
                     AKELLVKYNNEVDYIYQGNASDFEALKAKNLNGYVFLPDADGDIGYFVNENTSEIYYF
                     HPSGYLELVNQQQNNK"
     gene            complement(14397..15491)
                     /locus_tag="OE968_002941"
     CDS             complement(14397..15491)
                     /locus_tag="OE968_002941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HCP7220202.1"
                     /translation="MQDKKIYLNIVLTVVVSYILIKVIDNYKYFFGVISLLMSLLTPF
                     IIAFVLAYIFNPLVKFLESKLNFKRIYSLLLTYGVLIVILISFILFTVPSIVNSLADL
                     VAQIPTYIDKTEQFLFDLGKSLQSVDPNTLKEYGDKIMSVMPKFSNLLIGSLGGIFST
                     TFSVGKFIVQFLLGFIICFYILLEKEKFLLFTKKVVYISLGKKYGDFIIELCQSLNLN
                     IGKYFTGKILDSFIVGVLSGIGLYFLKSEYALLFGTLMGVMNMVPYFGPVIGMAPVVI
                     INLFSNPTIALTSLIYLIIIQQVEVTFIEPKIVGGQLGLSPFFTILAVTVGGGFFGIP
                     GMILSAPVMGVIKIYFCEFVNRRHDKIQME"
BASE COUNT         6048 a         1924 c         2502 g         5116 t
ORIGIN      
        1 taatttgaat tttttcaata aaaatttaca aaaatgaaaa aacaaacaaa aaagaattga
       61 agatttaagt tgttatttaa atatatatat attaagattt tctgctgaag atactaaaaa
      121 aataatattt ttcataattt taaaaataat aataaaaaaa tgaaaataca ggcgataatc
      181 tattgagtaa acatagaaaa gatgatatta taagtatgtg ctaaaatggt taaagcaata
      241 ttaatattaa atttaactat aaaacaaaag ggggcgtttt tttatgtcaa gtacagaaag
      301 cgtatctaaa aaaagtggtc atccgaagag tttttggctt atttgcatga caattttgtg
      361 ggaaagattt agttattatg gtttaacagc tttattggta ttatttttta cagcaagtgt
      421 agctcaaggt ggtttaggtc tttctactca agaagcaaca tccatgtttg gcttatttac
      481 aggtcttata tatcttacac cattagtcgg tggctggtta gcagataaag ttttaggtca
      541 acaaaaatgt atttctatag gtgcactttt aatagcaata ggagatttcg tactatttgc
      601 ttcatctaca tctattgcaa tggtttgggt aggtctatca ataattattt taggaaatgg
      661 tttttttaaa tcaagttgct caaatatagt tggggatata tatcctaaaa ctgatgtgtc
      721 aagaaaagat gcagcataca gtttattcta tatggcagta aatgtaggag catttatagc
      781 tccaataata tgtggattgc tttctgataa tgtatttgca gtaagaggag caagtggaga
      841 tatagtatct tatggatata agatggcatt tttaatttgt ggtataggca tgatgttagg
      901 tatgattata tttacacttc ttgcaccaaa attattaaat gaagtcggaa aatatcctgt
      961 gactaaaggt aataaaggtg aaaaaattga gtatggacca cttactaagt tggagaaaaa
     1021 taggataata gcaatggtta ttttattttt atttgtggtc ttattctgga cagcatacta
     1081 tcaaacacaa agttctttta tgatttatgt aagggataat gtaaatagaa ctctatttgg
     1141 atttgaaatg ccagtagcat ggcttacatc actaaatgct atattatgtg tggctttatg
     1201 cccagtatta gctaccctat gggttaaatt atctcatacc aaaagaggtg atttctctat
     1261 tccagttaaa atgggattag gaatgataat aatgggtgtt gggtttatag ttatggtatt
     1321 tgctacatta gctaatggtc cagatggaat ggtaaaggct agtatattgt ttatagtatt
     1381 gacttatata tttacaacag taggtgaatt attcttatct cctataggac ttgcaatgtt
     1441 caataaatta gctccagcta agtatgctac gttgtctatg ggagcctggt atctaacaag
     1501 tttttttgca agtttattat caggaaagat tgctggtttt acagccacac ttggtttttt
     1561 acagatattt ggaggaatag caacagtttt aataatattt ggtttaatat tattgggaat
     1621 aagaaatgta ttaacaagat taatggctat ggatttacta acaaaagaaa aataattcat
     1681 gacgaattat tgtaaataaa tgaattactt taaataaagg aagttacatt taaatataaa
     1741 attaaatgta atttcctctt tgattatgaa aaaaagcttt acacaaatag atattataat
     1801 taaaattata attgtgataa ttagagtgta taagatttat ataaattata caaaaaatat
     1861 ttatgtaata aactttacat acttatatat ttagttattc aaactattat ttcgaggagg
     1921 tcttgttgtg aatataaaag atagattaag tggattaaga aaatttatgg aagaaaaaaa
     1981 tatagatgcc tatatgattc catcttctga taatcaccaa agtgaatatg taggagatta
     2041 cttcaaatca agagaattta tatcagggtt taatggttca gcagggacgg ttattgtgac
     2101 taaagacgaa gctgggttat ggacagatgg aagatatttt atacaggcag aatctcaatt
     2161 agaaggaagt acaataaaat tattcaaaat gggacaagaa ggttgcccaa ctacagatga
     2221 atatttatat aaaaatattc ctgaaggagg aactttagga tttgatggta gagttatatc
     2281 tgctagagaa ggagctacat tagctgaaaa attatctaaa aaaggtataa agatagaata
     2341 tcagtatgat ttaatagata gtatatggcc agatagacct gctttatcag atagtaaagc
     2401 atttttatta gatgttaaat attgtggaga aagttttagc tcaaaattag ctagattaag
     2461 agaaaaaatg agtgaaaaag gtacttctac tcatgtaata actactcttg atgatatagc
     2521 atggttattc aatataagag gtggagatgt taaatataat ccagttgtac tttcttatgc
     2581 agtaataact ttaaaagaag tttatctatt tgttgatgaa agtaagttaa atgaagaaat
     2641 actaaatgaa ctagctaagg aaaatgttca aataaagcca tataatgatg tgtatgaatt
     2701 tgtaaaaaat atagacaaaa ctgaaaaagt tttattagat ggaactaagc ttagttatac
     2761 aatttacaat aatatacctt gtgaagttga gaaagttgat gagttcaatc cagtaatgtt
     2821 ttttaaagct caaaaaaatg aggtagaatt agaaaatata agaaattcac atgtaaaaga
     2881 tggtgtagct ttcactaaat ttatgtactg gttaaagaaa aatgtaggta agatggaaat
     2941 cactgaaata agtgctactc aaaaattaga ggacttaaga agagagcaag aaggtttctt
     3001 tgagccaagt ttcaatacaa ttgctgcata taaagagcat gctgcaatga tgcactatag
     3061 tgcaactcca gagtcaaatt ataaattaga ggcagaagga ttatttttag tagattcagg
     3121 tggacaatat tatgatggaa ctactgatat aactaggact acagttttag gacctataag
     3181 tgatgaatta aaactacact ttacttctgt agcaagagga atgataaatc tttctaaggc
     3241 taagttcttg catggttgta gaggatataa cttagacata ctatctagaa gttgcatgtg
     3301 gaatatggga attgattatc aatgtggaac tggacatggt ataggatttg tgctaaatgt
     3361 tcacgaagct ccaaatggat ttagatggag agtagtacct gaaagatttg atagtgcagt
     3421 tcttgaagaa ggaatggtaa ctactaatga accaggtata tatatagaag gttctcatgg
     3481 tataagaaca gagaatgaaa ttgtagttag aaaagctgaa aagaatttct atggtcaatt
     3541 tatggaattt gaagttgtta cgttagctcc tattgactta gatggtatag taccagaatt
     3601 aatgaataag gatgaaaaag attatttaaa ctggtatcat aagttagttt atgataaaat
     3661 atcacctttc ttaactgatg aagaaagaga atggttaaaa gtttacacta gagctatata
     3721 gtttgtacta gatacaataa aaatcgaggt attataatgc ctcgattttt tattgtatat
     3781 tttattaact ttaaaaaatt tttaatttga taattctact aattttttat tcattataag
     3841 tagtataatt ccaaatatca ataaaaatga tggtatcact atgaagactt gtaacatacc
     3901 aagttggtct ataatagctt gcgtatagcc agataattta tttgctgcaa atttgcctaa
     3961 aaaccaaaca cccattagga atgaaatata cttttcaggc gaaagtttat ttaccatacc
     4021 atacccgact ggagaaaagc aaatttctcc tatactttgg aatgttaaaa atccaactac
     4081 ccaaaataca cttgctttgt gaattgaatt agggtctgtt cctgtttgta taactgctac
     4141 tatcataaac aaaaatgcta tggctaatag tataaaacct aagctcattt tttttggcac
     4201 acttaaatcg ccttttttag tttgagataa ttttacccat actaaagcag agataggtcc
     4261 aagaataaca caaaggagac cattgtatga atctatccat gaagtaggaa tttgaaaatt
     4321 gccaacagta agatttatgt gttcctttgt atagagtgca atagacatag aggcttggtt
     4381 atatgctatc caaaaaaata ctgtgaaaaa agctaacacc aatattacta ttattctttt
     4441 tttctcaatc aaagttaaag gtcttgaagc tagcattttc ttatattcta gtgattttct
     4501 tatagactct ctcccgttac tagggtcatt attcaaaggt ttataaaact ttctgtttcc
     4561 aaatataaag aagaataaac ctattagaac cgtaattgat gaaaataaaa atacatatct
     4621 atatccatac atacttatag ataatccgct tttcatagca aaccattcat tagcaactaa
     4681 accgcatatt aaagggccaa ataaggtacc tagattagta gccatatacg taatagagaa
     4741 agctccatct tttcttgggt catcattggt atataagttt ccaaccatag tatgtaagtt
     4801 tcctttataa aaacctattc ctaatccaga taaaaatatc atgatgttta tatccatctt
     4861 actatttgct atgtatccta gaaaataacc aattgaaacc attagcattc caagtataat
     4921 acagtttttg ggacctaaaa atctatcact gacccatcca ccaataactg gagagaaata
     4981 agtccatgct aaaaaagatg caagcattga tgcggattct gctggtgtta accctaaacc
     5041 acctttggag acttgttcag ctaaaaacaa taataatacc aatttcatac catagtatgc
     5101 aagtcctaca aaggtaaata ttgaacagca gaaatataaa tctctaggtt gtttaagttt
     5161 ttcttgcgtt tttaaaactg acatatgtcg agaacctcca gataaatagt ttaacaaaat
     5221 tttaccatac tatatgagta tatgtttttt tcatatagac gtcaacttgt aagataattt
     5281 aattaagtcg aaatatatgt aaaaatagta tcatttttgt gtattcagta atattttttt
     5341 atgataatat atgttattat tatattaaaa tacaaacata tttatggaaa ggatatgcca
     5401 atttagtagt tagattgatt gtttggcagg tgggatgagc tatgataaga aagaaatctg
     5461 aattacaagt agaagtaaaa gaaaatttaa atggtggtat aggaaaggtt aagcttgaaa
     5521 acataataca aaatgaagag cttaaaggaa aaggaagact atttaaaaga gtagctttac
     5581 cagtaggaag ttcaattggt gtgcatgacc atacaacaga ttttgaagta tattatatac
     5641 taaagggaaa aggtaaagta tttgataatg gggaatttgt agaagtaaat gagggtgatg
     5701 tagtgtatac agctgatggc gaaaaacatt ctatagaaaa tataggagaa gaagatcttg
     5761 agtttgtagc actagtttta tatatgtaaa atatggagga ggagtcatga caggcaagat
     5821 agaagaaatt aaggacaaga taaatagatt ttgcaactcc aatttaaatc aagaatacaa
     5881 agatataagc tttaaaattt tgcaaaacct tttagataat aataaagaga taattcattc
     5941 ttctagagct gatatatggt cttcagctat actaaatata gttttagaac aaaatctttt
     6001 atacaataag aagcatccac tacatataac aaaaaaagag ttttcaaaac aaataggtgt
     6061 ttctttaaat actataaata ataaatcgtc tttaataaaa gatgtttgta gtattgactt
     6121 tttaaatcaa gatactatag ctatttctaa tgtagaattt tgggtaaaag agaccaattc
     6181 caaatcaaag tctgtagatt tagatttaga aaagaaaaaa atactatata aaagatatat
     6241 taagctatca caagatgcga atagtgatat tgaatcaatt agatatatgg aggaagctgt
     6301 aaatataggt aaaagtatga ttactaaaga agataaagaa cttggatttt ggaaaggttt
     6361 atctaccaga gcctatatga tagcacttga atcccttgct agaaagttag aaagtattaa
     6421 taatctaaag gagtccaaaa aagtattaga atatttaata gaaattaatc ctagtgatga
     6481 gcagggaata agatacaaat tattaaatgt attaattaga ttaaatgata gaacttcaat
     6541 aaataaatta tttgaacttt ataaagaaga aaaatctgct acatggatgt acagtaaagc
     6601 tctttattac tttaaaaata aaagtatgtt tttggcaaat gattctatta aggttgctag
     6661 aagtaaaaat aagtacgttg gattatattt gttagattgg cgaaatgctt ttggtagaga
     6721 atttgttaca gaggaagaaa aggcagaagc tgtctattac tatgatgaaa acatagtgat
     6781 ttggaatgaa gttaaaggtt ctatggattg gctattaaaa aaaatgttgg aattttcata
     6841 aaaaaaacta ctccttactt ttatataagt aaaaggagta gtttttaatt tatacatcta
     6901 gttttaaatc ttcaggtttt attagacctt tttttctcat aaattctgaa atcaacaaag
     6961 ttacaatagc aggaagtata aaattaagta aaagtatacc aacccacata gatatacctc
     7021 cttttccagc actttgcata gcagttactg ttccaaattg tccaaccaat ccacaagtac
     7081 ccataccaga accaatagga atattctcca ttttgaatat tgttgtagat aatggtccaa
     7141 gtaatattga agctacagta ggtggtatcc aaattttcca attttttatt atattaggta
     7201 cttgcaacat agatgtccca agaccttgtg ccacaaggcc gccaactcca ttttctctaa
     7261 agctcataac agcaaagcct accatttggc aacaacaacc tacagttgct gcaccaccag
     7321 caagaccacc taaacttaac atcatacaaa tagctgcact acttataggt aatgtaagag
     7381 ctattccaac aagtgcagag actaaagctc ccattattat aggttgcata gttgtagctt
     7441 gcattattat atttccaaat gaagtcataa aagcagaaac agctggacca ataagttcag
     7501 ctacaagtac tccaattagt attgttacag caggtgtaac caatatatct atttttgttt
     7561 cttttgaaac taattttcca acctctacag caaaaagtgt agcgacaaat gctccaacag
     7621 gtcctcctaa ttcattacca caagctccaa caagtgcaca agaaaatagt acaagtggag
     7681 gtgcttgaag tccatacgca atagccactg ctatagctgg accagtaacc tgtttagcaa
     7741 gagggcttat aacttcagta aaaagagaaa tattgaaatt atctcctaat gtattgaaaa
     7801 ttgttccaat taaaagggac gaaaaaagac cgagtgccat ataacttagt gcgtcaataa
     7861 gatacctttg aacagaaatt tcaatatttt ttcttttagc aaatgatttg aaatttcttt
     7921 ttttataatt gatttccaat ttaaaatcct cctcatataa tataagtata atttcttttt
     7981 aattaattat ataacttttc agctgacaag acaaatgtta tttcactaaa attagactat
     8041 tgtaatagta agaaattaac attaatttta gttttaaatt ttaaatttat ggtttataat
     8101 tagtataggg atattctgaa atataataat tttccagttt atcccaatat ttaacttagg
     8161 tagattgctt acaaaacaaa tgattatata ttaggctaaa aggaagtgga tagatgatat
     8221 ttgtaaaaaa taagaaatac agaaaaattg ccataattat atctattcct atattgcttg
     8281 ttgcgcagta ctaccttttt aaatttggaa tacttagacc aatggtaaag ggagtagaaa
     8341 ttgaaattgt agatggggaa tatgttaaag atatagataa atatgtagta aaattaaatg
     8401 aaacagttac tttgtctaca ggtgaatata ttaaggttcc ttcgtatgct aaaaatccaa
     8461 atatttggtt taatgtattg gataactcag ggactttaaa aatagatgga aataaaatga
     8521 cagcattaaa ggttgggtat tcttctgtgg gtatcatgaa aaattcaaga gtattaaaaa
     8581 aggctactat aaaagtagta gacccagagg tagaatcact agatatggag attaatgggg
     8641 atttaaaaca tgttggtgat agtgctacta tagaaagtac aatagaagtt gattatgata
     8701 agtttaaaaa atcatataag ccagtttata agagtagcaa tgaaaatatt ttaaaaatca
     8761 aaggaaataa agtaagtgca gttggagttg gtaaagctac aatatatgct aagtgtggaa
     8821 ataaagaaat tgagagaaca tttaggattc aagctagagt tgctgaaata aatatggatg
     8881 atataaaaat agaagttgac cagaatgaaa aattgaaacc agatataata acttctccac
     8941 ctggtttaga accaccaaaa atatattatg agttagtaga ttcaaaatta cctgtagaaa
     9001 gagcaataag tttaagtagt aatggaaatg ttgtagggct tagagaaggt aaagataggg
     9061 tgagaataac ttgtggagat aaatctaaag taataacagt aacagtagtc aaagaaacta
     9121 taacgaatga ctatatacaa aacttggttg gttcacataa aatagtaaac aataaagtta
     9181 ttattaaact tgaatgggat tatatgaaag atgtctttga ttatgatata tatcttaaag
     9241 ataagttgtc aggagaatca tttaagaaaa ttaaatctat aactataaat gaaagtgatt
     9301 taggtaagtc taacaaggta tatgcaacta tagaagtaga tatgaagggt aatcaaaata
     9361 tagattttga tatttatgtc ataggtaaaa aggattcaga tacaactaag ccaagtaatg
     9421 taataaatat taccaatgga aatggaaatt caaataatga taataatatt aaagatatga
     9481 gggtagaaaa tatatcagct aatgttgata gagataataa tgtcattaga gttaactgga
     9541 gtagtatatc tcataaggac tgtacttaca gtatatatgt aaaaaataat actaatggag
     9601 atggagaatt tactctatat caaagtgata tacagggaaa tgagcatact ataagtattc
     9661 ctgaaggaga tttaaatcta gatatttatg ttgttgcaaa ttataatgga aatagctctc
     9721 aaaatagtga tgttataaat gtaagataga tttgtataca aattgaaagt gttgagttta
     9781 tttaaatatt aaattaagaa aaaggatagt atagggtaat tatactatcc ttttttgtta
     9841 caatatatag gtttaaaatc tctagtaata taaattataa aaagtcttat ttacacaaat
     9901 ctatagatat tttttttatt aatcaatatt gtcttaaatt gaacttagtg cggcttctat
     9961 tgcatgtatt actgtcgtat caaatagtgg aatagaagtg tcattttgtt taattaaaag
    10021 acctatttct gtacatccta atataacagc ctctgcacct tgtttgccaa gcttatctat
    10081 aatagataag aaagcttttt ttgaagattc agatataatt cctaagcaaa gttcattaaa
    10141 tattgtgtca tttactatta tacggtcttc ttcatttgga attaagactt caattccatt
    10201 attaataatt acatttttat aaaaatcttg ttccattgta tatttagtac ctaataaggc
    10261 cacttttttt atttcttttt cccttaatac cgtagcagtt acatctgcta tgtgaagtaa
    10321 tggaatatgt atactttctt gtattttatc tgatacctta tgcatagtat tagtacagat
    10381 aacaataaaa tctgcccctg cctcttgtaa tttaattgca gcatcagcta aaattttggc
    10441 gcttttttcc caatttccac tagattggca ttcttcaatt tcttgaaaat ctacactgta
    10501 aagtatacat ttagaagagt gtagtccacc taatctttct tttattactg tattaataac
    10561 ttgataatat gtaatggtac tttcccaact cataccacca attaagccta tagtcttcat
    10621 attatacctc tcttatttat ttattttgaa atagctattt acaaatacaa gtatagcatc
    10681 taaaatagaa gcatacaata ataaaattgt atggagtaca attataatta agaggagtaa
    10741 ttatatgcca ataaattctt ttgaaaacta tcctatgaca tggaaaccaa agttagataa
    10801 ccgaaaacca ccaatatata aaactttagc aatgttatta gaagaagata ttaaaagagg
    10861 aaatttaaat cctggagata aattgcctcc acaacgggaa ttagcagatt ttctagattt
    10921 aaacttaagt acaataacac gagcatttaa actttgcgaa gaaaagggac taatatgtgc
    10981 aaaagtggga aagggaacat tcatttcttc tgatgtaaat gtaagtaata cattattata
    11041 tcaaacggaa tcaaaagaca taattgagtt ggggacagtt catcctccgt atgagcaaaa
    11101 tacatatatt attgacttta ttaaaaatgt actaaaacaa ccagaaatgg ataggttttt
    11161 acaatacatg tctccatctg gcacatatat gcaaaaaaag tcaattgcaa aatggataga
    11221 aagaaataat gtatacacca gtgaagaaaa tatattatta tctacaggag ggcaaaatgc
    11281 tatatgtgca actttactag gattatttaa agctggtgat agaattgcta cagattcttt
    11341 aagtttttct ggaattaagt caatagctaa aatgataggt attcaattag tcccaattcc
    11401 tcaagaaaat aatgaaatat cgattgaata tcttgaaagt tattgtaaaa atgaaaatat
    11461 aaaaggcata tatcttatac cagattatca taatccaacg acacatacta tgtctgattt
    11521 atctcgtaaa aagatagcca agatagcaaa gcaatataat ataataatta ttgaagatgc
    11581 tataaatagc atttttagag atggtataca aactcccata ttttctttag ctagtgataa
    11641 tactatatat atttttagta catctaaatt tttatgtgct ggtcttagag tagcatttgt
    11701 agttgctcca aaacgatata tagaaaattt agaaaatgca ctatataata tgaatctaat
    11761 ggtttctcca tttacagcag aaatagtaca ccgtttatta tattctccta ttatagataa
    11821 aattatagaa gagaaaagag atgcaattat agaaagaaat gaagttgctg ataaagtttt
    11881 gtcagattat aatttgattg gtgataagaa ttgcagtttt cgttggttac ttcttcctga
    11941 tgaattggat ggaaaatcat ttgaaatttc tgcaaaaaat ctaggagttc aagtatattg
    12001 tgccgaacga ttttcagtag gaaactctac agttccaaaa gcagttcgta tttgtgtaac
    12061 agctccaaaa gatgtagaag aattagaaaa agggcttaat ataataaagt cacttcttaa
    12121 gagttaaatt tattttacta ttatttaatt aaataaataa aaaggcggag aaatttatta
    12181 taataaacct ccgcttttat tatttaatga aatactttac tttttattaa aaaatttaat
    12241 tttaataatc ttgaaaatat aatcgtttta tggtaaaata attcttaaaa atagaaaaaa
    12301 ttaatcattt gttaaaaaaa atgcataatt tattgtaatt tattgacgaa ggttgaaaaa
    12361 tattcataaa tgtgcgaaat aacagaaaaa atgcaaaaat taattcaatt tcatttgtta
    12421 taaaatctat atggcaaaat taaatctgcc tatcagaatg atataaacac atcagaaagg
    12481 aggacgctat caaataatac aagtagttaa ctttgatagc aaaaaattat gaatgaacaa
    12541 actagaatat ccttagagag agctgctgaa ttaaaatcaa aaattgatga ttatattcag
    12601 gctagaaaaa cgattaacag aggtcttgaa aaagaagaag agataaataa acgaaaacag
    12661 aaaatattaa gtatcttaaa tggaactgaa gaggattgga ataactacaa atggcaatta
    12721 tcaaatagaa taacagatgt agatacttta tcaaaaatta taactctaac taaaaaagaa
    12781 aaagaatata taaaagaggt tggtactcaa tttagatggg caatatctcc atattatttg
    12841 agtcttatag acccagaaga tatatgtgac ccaataaaat tactgtctat accaacacat
    12901 atagagttgg aagatgagca agaagatttg gacccaatgg gagaagagta tacaaaccca
    12961 gcaggatgta taactagaag atacccggat agattaataa taaatgtaac aaatgagtgt
    13021 gctatgtatt gtagacactg tcagagaaga agaaatattg gacaacaaga ttctcataag
    13081 tcaaaagcta ttatccaaga atctatagac tatatcagag aaaatgaaga aataagagat
    13141 gtactagtaa ctggtggaga tgctcttaca ttaaaagatg attatttaga gtggattctt
    13201 agccaactta aagagatacc acatgttgat tatgttagat taggtactag gactcttgtt
    13261 acaatgccac aaagaattac agatgaattt tgcaatatgc taaaaaaata tcaccctgta
    13321 tatataaata ctcattttaa tcatccaatg gaaataacta aggaatctaa agaagcttgt
    13381 gaaaagttag caaatgcagg cgttccatta ggaaatcagg cagtattatt aaatggaata
    13441 aataatgata aatttgtaat gagatgttta aatcaagaat tactgaaaat aagagtaaaa
    13501 ccttattata tattccaaag taaacatgta aagggaacaa aacatttcaa tacatcagta
    13561 gatgatggtc ttgaaatcat ggagtattta agaggatata catcaggaat ggctatacca
    13621 acatatatag taaatgctcc aaaaggagga ggaaagactc ctttgcttcc tcaatacctt
    13681 gtatcaaaag gaacagatta cgttatgctt agaacatggg aaggaaaagt tataaaaatg
    13741 gaagatgaac ctgctgtaga tataaagaaa cttataaaag aacaagcaca ggattaaaaa
    13801 aatatttaaa gtttataaaa agaaacaact ttaaaataaa aagaaaatgg atgtcaaatt
    13861 tatatcaatt tgcatccatt ttttattagt tatttattat tttgttgttg attaactaat
    13921 tcaagatatc cacttgggtg gaagtaatat atctcagaag tattttcatt tacaaagtaa
    13981 ccaatatcac catctgcatc tggtaaaaat acataaccat taagattttt agcttttaat
    14041 gcttcaaaat cactagcatt tccttgatat atgtaatcaa cttcattgtt gtattttact
    14101 aaaagttctt tagcttgttc ttgagtcaat ttagtatttt ggcttacagg aacattcttt
    14161 tgagaatctg cataagaaga ttcatttact ggtgcagtta ataacaaaca agataaaact
    14221 aataaagata taagtgcttt tttcatacta aaaccctctt tcatgtttaa ttatataaga
    14281 ttcattactt aataatattg tatgtttcct ataattaaat attaccatta aagagaataa
    14341 tattacagtt acacagctgt aacttttgat tacaaaatcg taattaaatt gtatttttat
    14401 tccatttgta ttttatcatg tctacgattt acaaactcac agaagtatat ctttataacg
    14461 cccatcacag gagcagatag aatcatacca ggtataccaa agaatcctcc accaacagta
    14521 actgctagga ttgtaaagaa tgggctaaga cctagttgtc cacctacgat ttttggctct
    14581 ataaatgtaa cttcaacttg ttgaattatt attaagtaaa ttaaagaagt taaagcaatt
    14641 gttggattgg agaataaatt aattattaca actggtgcca tacctattac tggaccaaaa
    14701 tatggaacca tattcatgac acccataagt gtaccaaata atagtgcata ttcagatttt
    14761 aaaaagtaaa gaccaattcc agaaagtact ccaactataa aagaatctaa aatcttacct
    14821 gtaaagtatt taccaatatt taaatttaag ctttgacata gttctattat aaagtctcca
    14881 tattttttac ctaaggaaat ataaactact ttttttgtaa acagtaagaa tttttctttt
    14941 tctaataata tatagaaaca aattataaaa cctaaaagaa attgtactat aaattttcca
    15001 actgaaaatg tagtgctaaa tatcccacca agtgaaccaa taagcaagtt actaaattta
    15061 ggcattacac tcataatttt gtcaccatac tcttttaatg tattagggtc aactgattgt
    15121 aaactcttgc ctaagtcgaa taaaaactgc tctgttttat ctatgtatgt aggaatttga
    15181 gcaactaaat cagctaaact atttactatg gatggaactg taaataatat aaacgaaatt
    15241 agtataacta tgagtacacc ataagtaaga agtaacgaat atattctctt aaaatttaat
    15301 ttactttcta agaactttac tagtgggttg aatatatatg ctaatacaaa tgctattata
    15361 aatggtgtta gtagtgacat taataaactt atcactccaa aaaaatattt gtaattatca
    15421 ataactttaa tcaagatata tgaaacaact acagtgagta caatatttag ataaattttt
    15481 ttatcttgca aaataacaca acctttctta tatttattaa atttagatat acttaaatct
    15541 aagttaaagt taatatttat agcttattat acaataaaaa gcagtattaa
//
LOCUS       DAJMZY010000098        15418 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.099, whole genome shotgun sequence.
ACCESSION   DAJMZY010000098 DAJMZY010000000
VERSION     DAJMZY010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15418)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15418)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15418
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.099"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            complement(88..1185)
                     /gene="ychF"
                     /locus_tag="OE968_002942"
     CDS             complement(88..1185)
                     /gene="ychF"
                     /locus_tag="OE968_002942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HCP7220203.1"
                     /translation="MKLGIVGLPNVGKSTLFNAITQAGAESANYPFCTIDPNVGVVSV
                     PDERLNKLQELYNSEKIVPTAIEFCDIAGLVRGASKGEGLGNKFLSHIREVDAIVHVV
                     RCFEDENVVHVDGSVDPLRDIETINLELIFSDIEILERRINKTQKAAKADKTLGSELD
                     LLKSIMSTLEESKCVRTMEFTEDEQTFVNSLDLLTSKPVIYASNVSEDDLADNGENNK
                     YVQQVKAFAETEDAEVVVVCAQIEAEISELDSAEEKKEFLETLGLEQSGLDKLIKSSY
                     ALLGLISFLTAGPKEVRAWTIKVGSKAPQAGGKIHSDIERGFIRAETIAFNDLVEHGT
                     MAAAKEKGLVKLEGKEYIVKDGDVILFRFNV"
     gene            1501..2766
                     /locus_tag="OE968_002943"
     CDS             1501..2766
                     /locus_tag="OE968_002943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HCP7220204.1"
                     /translation="MVNTKKIINLGNNINLTLIKTEKFKSNLISLYVQRLLDEKETTK
                     NALIPSIIASGSSKYPSARAISNKLDDLYGSSMGADAVKRGERQVLSFKVINISEKYL
                     DESIFEEVVEFFNEVINNTLVVDGGFKEEYLNIEKENLREKIQSIINDKKEYAQDKCI
                     EAMCKGERYSVSEFGYEDEIDSITSRELYEHYKNILKTSPIDIVVEGNFDEDKVVDII
                     SKNLKFEREEIINIPRADFIKNVDEVKVIDEQMEITQGKLVMGYRANVDYADIDKYYA
                     LVVGSNVLGGGPHSKLFVNVREKESLCYYIFSSIEKYKSIMFISSGIETKDYDKAVEL
                     IKKQVESVKAGDISDEELENSKLALVNSMKSITDNIGGMSDFVFSQSMAKTNSEVQDI
                     ISSIEKVTKKDIVEAIKNIELDTVYFLRN"
     gene            2781..4067
                     /locus_tag="OE968_002944"
     CDS             2781..4067
                     /locus_tag="OE968_002944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HCP7220205.1"
                     /translation="MEKIVNDILKEEVYYEKLQNGLDVYFMPKRGFMKKYAILATNYG
                     SNDLEFVPIGEDKKIRVNEGIAHFLEHKMFEQPDGGDAFDKFSKLGVNANAFTNFTMT
                     AYLFSATENFYESLEHLIDYVQTPYFTDENVEKEKGIIAQEIKMYNDDPDWNVYFNCL
                     KAMYVNYPARIDIAGTVDSIYKITKEELYKCYNTFYNPGNMALFVVGDLDVEKVIDVT
                     KKSNNYKVDKLSKSIERFYPEEPEGVKEKEVIEKFPISMPMFNIGFKDSNVGLKGKEL
                     LRKEIVTDILVGMLFKKGSKLYEDLYMQGLINENFGAGFSSQVDYAFSIIAGDSKEPK
                     KVKEIILDYIEKSKKEGLSKEEFERTKKKKIGSFIKCFDSINFIGNSFISYVFKDINL
                     LEYLDVIKDITFEEVEERLKEHFKEEYCVISIVEPK"
     gene            4461..5207
                     /locus_tag="OE968_002945"
     CDS             4461..5207
                     /locus_tag="OE968_002945"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HCP7220206.1"
                     /translation="MDRVAFTLFGIDIMWYGILMACGMILGTLIAIKEAKRVGIKEDD
                     VLNIAIIAIPVGLICARIYYVVFNWSYYAQNMSQIFNFRGGGLAIHGGLIGGILAGYI
                     YTKIKNINFLKMADTVILGMPLAQAIGRWGNFINGEAHGGATNLPWGIMVDGVKVHPT
                     FLYESIWDFGIFIVLLLFRKNKKYEGQVIVTYITLYSIGRFFIEGLRTDSLMLGPLRM
                     AQVISLIGVIGGIIAHVYLSKKNKNNISEE"
     gene            5237..6172
                     /gene="rsmH"
                     /locus_tag="OE968_002946"
     CDS             5237..6172
                     /gene="rsmH"
                     /locus_tag="OE968_002946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HCP7220207.1"
                     /translation="MEFHHVSVLLNECIENLNIKPDGVYVDCTMGGAGHSKEIVKKLS
                     DKGLFIGFDQDKNAISTAKERLSEYESRVKFVHSNFENIKEELEKIGVYKIDGVLADL
                     GVSSHQLDEADRGFSYMQDAPLDMRMDVRCEFSAYDVVNTYTEDELTKIIKDYGEDNW
                     AKRIAKFIVEERANKPIETTGELVDVIKKAIPKKARIDGPHPAKRTFQAIRIEVNNEL
                     GVITKMINDASSIMNEGGRICIITFHSLEDRIVKNAFKHLASDCICPQHLPICQCDKE
                     SEVKIITRKPILPSEEEIEVNPRSRSAKLRVAEKI"
     gene            6658..7005
                     /locus_tag="OE968_002947"
     CDS             6658..7005
                     /locus_tag="OE968_002947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220208.1"
                     /translation="MKKNYKIHNLNEYKNKKKNNYKKRNKKKIGAKCILLIATFSVII
                     LNLCGYSKISEMKYDIYYLQKDLRKKEIVLEELKAKETEKTSIKEIELKAKELLNMDY
                     PKDGQIKYIDVDN"
     gene            7017..8996
                     /locus_tag="OE968_002948"
     CDS             7017..8996
                     /locus_tag="OE968_002948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein D"
                     /protein_id="HCP7220209.1"
                     /translation="MRKVKRISKKRLVLVLILACALFFCLVIRTGYLQLMKGNWLSTK
                     ALEQQTRDIPIEPKRGTIYDRNMKELAVSVTKYTVWCKPVEVEDKKEAAEKVAEILDE
                     DYKDIYALISKKNMALVKVKRWIDDDKASQIRDAKLSGIWVAEDNQRYYPYGNFAPYV
                     LGHTSSDATGISGVEMQYDKKLKGKPGKLIVSTDASGREIPQGMEKYYEPVQGNGLVL
                     SIDEVIQHYTEKAVQKAYELNNAKKVTAIAMNPKTGDILALASKPDYDPNDSRTPIYP
                     YYQEELEKYNDKDKIKGYYQMWRNPAVSDTYEPGSTFKLITSSSALEEGVIKDGEKFT
                     CTGSVTVGGRKIKCWRHYRPHGTQEFKQAVQNSCNPVFVELGSRLGVGKMYDYIESFG
                     LMDKTGIDLPGEAKGILYNEKNVGPVELATISFGQSISVTPIQLITAISSIANGGDLM
                     QPRVVKSYTDNKGNITETVKPKKVRSVISKETSKKMLEIAESVVTEGGGKIAYIPGYR
                     LGGKTGTAQKVIDGKYAPGKYICSFVGIAPCDDPQIVVLAIVDEPTGVSAFGSTTAGP
                     IVKEIMNDSLKYLGVKPVYKEEEKAEYEKKQVKVPDVRNLKIGDAVKALEDAKLKPDL
                     DADIELPEDTKVKDIFPKPGVKVNEDSSITLYFEN"
     gene            9163..10536
                     /locus_tag="OE968_002949"
     CDS             9163..10536
                     /locus_tag="OE968_002949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HCP7220210.1"
                     /translation="MECLTIKELVLATNGKLIYGDYNDCVSDIVIDSREANAQNAFVA
                     IVGENLDGHTFMKSAYDSGCKTFIKNESNGIKLESSDINLIEVKDTSLALGDISKYYK
                     EKFDIPFIGVTGSVGKTTTRDMIYSAISAKLNILKNEKNLNNHFGVPLTLFNLNKEHE
                     CAVIEMGMSGFNEIKYLVDIVNPKIAVISNIGLSHVEKLGSQEGILKAKMEITSNFDE
                     TNTLIVNGDDKFLSTLKEKEHVYKLKTFGFNKNNDVYCESYTMEEDSLTFICVINGKK
                     EEIFIPTIGEHNIYNAMSAILVGLCLNISLDYIKKGLKNFKGTKMRLDIIKNEKLTII
                     NDSYNASPDSMDAALKILGRYKGRRVAILGDILEMGEISEYGHRLVGKSSMNNTDIII
                     TIGENSVFIGEEAKQLGFNSANIYHFENREDVFNKLNELVKTGDTILVKGSRGMRLEK
                     IVEYLNK"
     gene            10577..11545
                     /locus_tag="OE968_002950"
     CDS             10577..11545
                     /locus_tag="OE968_002950"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HCP7220211.1"
                     /translation="MMLGITELTYTALIAFLIVIIIGPIFIPMLRKFKFGQTVRDDGP
                     QTHLAKNGTPTMGGIIMIVAILITGLTRVKVSHDMAVGLICIAGFGFIGFLDDFIKIK
                     LKRSLGLKAYQKIILQVALSFYVAFYQYTSSSSASQLMIPFTDFVINVGILYIPIMMF
                     IIVAIVNAVNLTDGLDGLASGVTLIVSVFFMLFASSIAGNTEVAVLAAATVGACLGFL
                     GFNSYPARVFMGDTGSMALGGAVVAFSVLTNSVLIIPIIGGIYFAEALSVLIQVGYFK
                     ATRKRFFKMAPIHHHFEQCGWPETRVVFIFWIITVVLAWISIIAVF"
     gene            11564..12919
                     /locus_tag="OE968_002951"
     CDS             11564..12919
                     /locus_tag="OE968_002951"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HCP7220212.1"
                     /translation="MDLKGKKVLLVGLAKTGISTIKHLDKLGASVIVNDIKDENKLRN
                     ILDELKSINDIKYILGHHPEDVDDIDMVVVSPGVPLDLPFILKLKNSGKYIIGEVELA
                     FKLSNNPIFIGITGTNGKTTTTSLVGEIFSRAKRDTYVVGNIGNPVIDTIETSSEESV
                     LVTELSSFQLESIDEFRPKVSAILNITEDHLNRHHTMEKYIEAKANIFMNQTVEDFCV
                     LNYDDEIVKSLADKCNAKVIYFSRTKKVNGGVYLENNDIIIDIDDKIKFLNKDDVSLP
                     GGHNLENCMAAIAIAYVCKIDLEVIKDVLMTFKGVEHRQEFVRNLDNVIYVNDSKGTN
                     PDSTIKAIQSYDRPIILIAGGMDKGSNFDELLETAKSYVKSLVLLGETASNIENCAKN
                     KGFNDIHIVKDMEEAVKTSYEISKSGDIVLLSPACASWDMYESFEVRGKDFKDNVNNL
                     K"
     gene            12971..14101
                     /gene="spoVE"
                     /locus_tag="OE968_002952"
     CDS             12971..14101
                     /gene="spoVE"
                     /locus_tag="OE968_002952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein E"
                     /protein_id="HCP7220213.1"
                     /translation="MPKENLKKQIDIRMKTEFDGVVFYTTMLLVFVGIVMVFSASFIQ
                     SSFKHNDAYYFLKKNVIYAVLGFIVMIITSRIDYSFWKKNATAIGAIAVVLLLLVLTP
                     LGIEANGAKRWLGIGALTFQPAEIAKFATIILTAKLIEKNYDKIKSLTKGVVPLLVVP
                     GIFFALIILQPNLSTAGTVILVTFVMIFVAGMDMKIVFAMIGSGAALFAALVIAEPYR
                     LSRVTSFLDPFQDPLGKGYQVIQGLYALGSGGLFGLGLGKSKQKYFYIPEPQNDFIFA
                     IIGEELGLIGCIIVIMLFVVLVYRCVRIALKTSNVFACMVVIGIGAQIGIQAALNIAV
                     ATSSMPATGVALPFISYGGTSLTIFMGAVGIVLNISKHVKIN"
     gene            14119..15345
                     /gene="murG"
                     /locus_tag="OE968_002953"
     CDS             14119..15345
                     /gene="murG"
                     /locus_tag="OE968_002953"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HCP7220214.1"
                     /translation="MKVLLSGGGTGGHVYPAIAIANKIRDEHPDAEIIFVGTEKGIES
                     EIVPKYGFELKTVTVQGFKRKIDFDNVKRVFKLFKGLEQSRKIVKKFKPDIVIGTGGY
                     VSGPVLFNASMGKIPAIIHEQNSFPGVTNKILSKTVTKVLTSFEDSHKRFPEAAEDKL
                     VFTGNPVRKEILLSRKNIARKNLSISDEKRMVLCYGGSGGSRKINDAMRLVIKNMVNE
                     DIAFIFATGKSYYDEFMGSISDINLKPYQKVVPYLEDMANALAASDLVIGSAGAISLA
                     EITALGKPSIIIPKAYTAENHQEYNAKSIEKQGAGIAILEKNLTPESLNTAVFKLLGD
                     RELLVDMANASKTIGKPEAIDLIYDEIMKVYNSTQKSTSKKTKKEKVIKEVKEIKKET
                     TPSIEGQAKVIGIKKR"
BASE COUNT         6062 a         1666 c         2837 g         4853 t
ORIGIN      
        1 taattattat aaggtaatat tgtattatta taatcttagt tttttagtta ttatatataa
       61 tagtcaaagt gtatacgatt aatcatttta aacattaaat ctaaataata ttacatctcc
      121 atctttaact atgtattctt taccttctaa tttaaccaac cctttttctt tagcagcagc
      181 catagtacca tgctcaacca aatcattaaa ggctattgtt tctgctctga taaatcctct
      241 ttctatatca gaatgtattt ttcctcctgc ctgaggagct ttacttccaa cttttatagt
      301 ccatgctcta acttcttttg gaccagcagt taagaatgaa attaaaccaa gtaaagcata
      361 agaagatttt ataagcttat caagccctga ttgttcaaga cctaatgttt ctaaaaactc
      421 tttcttttct tcagcagaat caagttcaga aatttctgct tctatttgtg cacatactac
      481 aacaacttcg gcatcttctg tttctgcaaa tgctttaact tgttgaacat atttattatt
      541 ttctccatta tcagctaaat catcttctga tacatttgaa gcatatatta caggcttaga
      601 tgtaagtaaa tccaatgaat ttacgaatgt ttgttcatct tctgtaaatt ccatagttct
      661 tacacactta ctttcttcta aagtagacat tattgatttt aataaatcaa gttcagaacc
      721 taaagtttta tcagccttag cagctttttg agttttatta attcttcttt caagaatctc
      781 tatatctgag aaaattaatt ctaagtttat agtttctata tcacgaagtg ggtctacaga
      841 accatctaca tgtacaacat tttcatcctc aaaacatcta acaacatgaa ctattgcatc
      901 aacttctctt atatgtgata agaatttatt tcctaaacct tctcctttag aagctcctct
      961 aactaaacct gctatatcac aaaattctat agcagtagga actatttttt cagaattata
     1021 taattcttgt agtttgttta atctttcatc tggaacagat acaactccca catttgggtc
     1081 tattgtacaa aaagggtaat ttgcagattc tgcacctgct tgagttattg cgttaaatag
     1141 tgtgctttta cctacatttg gtaaaccaac tatacctaat ttcatattaa tcgtcctctc
     1201 tcttattctt ttttatattc tttatataac tttaaacaat caatctatag gattgcaaaa
     1261 ttgttttaat tatagacata catattgatt atacatcata tatatcaagc ttgtaaacta
     1321 gactttaaag catattgatt taaataatat ttgtatttaa tttaaataaa aatattgctt
     1381 ttagaaaata ataaaaagga tataattaaa tagaaggttt ttatatgtga gtatatgtaa
     1441 ttaaaaaata aataaatttc aattttaaaa ttgatgttta aataaaaata ggaggtacat
     1501 atggttaata ctaaaaaaat aataaattta ggtaataata ttaatcttac tttgataaaa
     1561 acagaaaagt ttaaatcgaa tcttataagt ttatatgttc agagactatt ggatgaaaaa
     1621 gaaactacaa aaaatgctct aataccatca ataatagcaa gtggaagctc taaatatcct
     1681 agtgctagag caatatccaa taaattagat gatttatacg gttcatctat gggagctgat
     1741 gctgtaaaac gtggagaacg tcaagtattg agttttaaag taattaacat aagtgaaaag
     1801 tatttagatg agagtatatt tgaagaagta gtagaatttt ttaatgaagt aataaataat
     1861 acgcttgttg tagatggtgg gtttaaagaa gaatatttaa atattgaaaa agagaattta
     1921 agagaaaaga tacaatcaat aataaatgat aaaaaggaat atgcgcaaga taaatgtatt
     1981 gaggctatgt gtaaaggaga gagatatagt gtaagtgaat ttggttatga agatgaaata
     2041 gatagtataa cttcaagaga gttatatgaa cattataaaa acatacttaa aacatcacct
     2101 atagatatag ttgtagaagg taattttgat gaagataaag ttgtagatat aataagtaaa
     2161 aatctaaaat ttgaaagaga agaaattata aatataccaa gagcagattt tataaaaaat
     2221 gtggatgagg taaaagttat agatgaacaa atggaaataa ctcaaggtaa gttagttatg
     2281 ggttatagag caaatgtgga ttatgcagac atagataaat attatgcttt agtagttggg
     2341 agcaatgtct taggtggtgg tccacactct aaattatttg ttaatgtaag agaaaaagaa
     2401 agtttatgtt actatatatt ctcttcaata gagaagtata aaagtatcat gtttatatca
     2461 tctggtatag aaactaaaga ttatgataaa gctgtagaat tgataaaaaa acaagtagaa
     2521 agtgtaaaag caggtgatat atctgatgaa gaattagaaa acagtaaact tgctttagtt
     2581 aattctatga aatctataac tgataatata ggtggtatgt ctgattttgt tttctctcaa
     2641 tctatggcaa agacaaattc tgaagtacaa gatataatat ctagtataga aaaggttaca
     2701 aaaaaagata tagttgaagc tataaaaaat atagagcttg atactgtata cttcttgaga
     2761 aattaatgga ggagatgtct atggaaaaaa tagttaatga tatattgaaa gaagaagttt
     2821 attatgagaa attgcaaaat ggattagatg tatattttat gcctaaaagg ggttttatga
     2881 aaaagtatgc tattttagct actaattatg gttcaaatga cttagaattt gtaccaattg
     2941 gagaagataa gaaaattaga gtgaatgaag gtattgcaca ttttctagag cataagatgt
     3001 ttgagcaacc tgatggagga gatgcatttg ataaattttc aaaattagga gtaaatgcaa
     3061 atgcatttac taattttaca atgacagcct acttattttc tgctactgaa aatttttatg
     3121 agagtttaga acatctaatt gactatgttc aaacacctta ttttacagat gaaaatgttg
     3181 aaaaggaaaa aggtataata gcacaagaga taaaaatgta caatgatgac cctgattgga
     3241 atgtatactt taattgcttg aaggcaatgt atgtaaatta tcctgctaga attgatatag
     3301 caggtactgt tgatagtata tataagataa ctaaggaaga gctatataaa tgttataata
     3361 ctttctataa tccaggaaat atggctttat ttgttgttgg tgacttagat gtagaaaaag
     3421 ttatagatgt aactaaaaag tcaaacaatt acaaagtaga taaactctct aagagtatag
     3481 aaagatttta tccagaagaa ccagaaggtg taaaagaaaa agaggttata gaaaaattcc
     3541 ctatatctat gcctatgttc aacataggtt ttaaagatag taatgttggt ttaaaaggga
     3601 aagaactttt acgtaaagag attgtaactg atatacttgt agggatgtta tttaaaaaag
     3661 gaagtaagct ttatgaagat ttgtatatgc aaggtttaat aaatgaaaat tttggagctg
     3721 gattttcgtc tcaagtggat tatgctttta gcataatagc tggagattct aaagagccta
     3781 aaaaagtaaa agaaataatt cttgattata tagaaaaatc aaaaaaagaa ggattatcaa
     3841 aagaagagtt tgagagaact aaaaagaaaa aaatagggtc atttattaag tgctttgatt
     3901 ctataaactt tataggtaat agttttatat cttatgtttt taaggatata aatctattgg
     3961 agtatttaga tgttattaaa gatattactt ttgaggaagt tgaagaaaga ttaaaagagc
     4021 attttaaaga agagtattgt gttatttcta ttgtagagcc taaatagaaa cttaatcata
     4081 ataagaataa ctaattaagt attagtttat gtttttaaat gtttattttg gtaaaacaaa
     4141 tttataaaat atatttatat aaattgaggt aaaaatttaa gagctataga taagaattag
     4201 aagaggttga tgtatatatg catcaatctt tttgattaaa aaatatctat gtacacttgt
     4261 aactttagtc atgagagatt cagtttaaaa aattttatag taattagata taatatagtg
     4321 tagggagttg tagaataaat tttaatattt tttgtagaat taacattaat gtgttatcat
     4381 aatttagtat aattacaatt aattgtaatt atagcatatt gctttggaaa tattttcaat
     4441 taatacaaag aggtgacgtt atggatagag tagcatttac actgtttggc atagacatca
     4501 tgtggtatgg aatacttatg gcatgtggaa tgattttagg aactttaata gcaataaaag
     4561 aagcaaaaag agtgggaatt aaagaagatg atgtattaaa tatagctata atagcaattc
     4621 cagttggact aatctgtgca agaatctatt atgttgtatt taattggagt tactatgctc
     4681 aaaatatgtc tcaaattttt aattttagag gtggtggact tgctatacat ggagggttaa
     4741 ttggtggaat attagctggt tatatataca ctaagattaa aaatattaac ttcttaaaaa
     4801 tggctgatac agttatactt ggaatgcctt tagcacaagc tattggaaga tggggaaatt
     4861 ttattaatgg agaagcacat ggaggtgcta ccaatttacc ttggggaata atggttgatg
     4921 gagtaaaggt acatccaact tttttatatg agtctatatg ggattttgga atatttatag
     4981 ttttattact atttagaaaa aataaaaaat atgaaggtca agttatagtt acttatataa
     5041 ctttatattc aataggaaga ttttttatag agggattaag aacagatagt ttaatgttag
     5101 gaccacttag aatggcacaa gttataagtc taattggagt tattggtggc ataattgcac
     5161 atgtttattt atcaaagaaa aataaaaata atattagtga agaatagttt aaaaagtgaa
     5221 tttaagggag gtaactatgg aatttcatca tgtatcagtt cttttaaatg agtgtataga
     5281 gaatttaaat ataaagccag atggcgtgta tgttgactgt actatgggag gagcaggaca
     5341 ttctaaagaa atagtaaaaa aactgtcaga taagggatta tttatagggt ttgaccaaga
     5401 taaaaatgct ataagcacag caaaagagag attgagtgaa tatgaaagta gagtgaagtt
     5461 tgttcacagc aattttgaaa atataaaaga ggaattagaa aaaataggag tttacaaaat
     5521 tgatggtgta ttagctgatt taggagtttc atctcaccaa cttgatgaag ctgatagagg
     5581 attttcttat atgcaagatg caccacttga tatgagaatg gatgttaggt gtgagttttc
     5641 tgcatatgat gttgtaaata cttatacaga agatgaatta actaagataa taaaagatta
     5701 tggagaagat aactgggcta agcgtatagc taaatttata gttgaagaaa gagcaaacaa
     5761 accaatagaa actacaggag aattagtaga tgtaattaaa aaagctatcc ctaagaaagc
     5821 tagaatagat ggacctcacc cagctaaaag aacttttcag gcaatacgaa tagaagtaaa
     5881 taatgaactt ggagtaatta caaagatgat aaatgatgct tcttctataa tgaatgaagg
     5941 tggaagaata tgtataataa cattccattc attagaagat agaatagtga aaaatgcatt
     6001 taagcattta gcatcagatt gtatatgtcc acaacattta cctatatgcc aatgtgataa
     6061 agaatctgag gtgaaaataa taactagaaa acctatatta cctagtgagg aagaaataga
     6121 agtaaatcca cgttcaagaa gtgctaagct aagagtagca gaaaaaatat aagtagttat
     6181 aaggctaaag aataatctta tatataaaat aagattatta taattaatta aaaagtatta
     6241 tatattttgt tgcactggta aagcaattaa aaaacaatta acactataag aaatgttctt
     6301 tgttattgag atatataatg aaaatttaga tataaaaata tagatataga tggtattaag
     6361 taatataatg gagaacttag gaatcagaga gtagatagtt agttacatat tatatttatg
     6421 gaagaaatta tctaaaaata ctagaagtga taaaaataaa tagaaattaa tatctaacct
     6481 atagattcat ataaaagtat aagtgaattt ataggttttt gttgtgtata gaaaaaaata
     6541 caattagatt gtgtaatagt gtattaattt agcgatgaaa ttttagagga agaaatatga
     6601 ttaataacaa atatagtata gaggaaaatt taaactatat actatcgggg tgagaatttg
     6661 aaaaaaaatt ataaaataca taatctaaat gaatataaaa ataaaaaaaa gaataattat
     6721 aaaaagagaa ataagaaaaa aataggagct aaatgcattt tactgattgc aactttttca
     6781 gtaataatat tgaatctatg tggttattca aaaatctcgg aaatgaagta cgatatctat
     6841 tatttacaaa aagatttaag aaaaaaagag atagtattag aggaactaaa ggcaaaagaa
     6901 actgaaaaaa catcaataaa agaaattgag ctaaaggcta aggaattgct caatatggac
     6961 tatccaaaag atggacaaat aaagtatata gatgtggata actaggggga atagatttga
     7021 gaaaagtaaa gaggataagt aagaaaaggc tggtactcgt tcttattcta gcatgtgcat
     7081 tgtttttttg ccttgttatt aggactgggt atctacaact tatgaaggga aattggttga
     7141 gtacaaaagc actagaacaa caaacaagag atataccaat agaacccaaa agaggaacta
     7201 tatatgatag aaatatgaaa gagttagcag taagtgtaac taagtatact gtttggtgta
     7261 aacctgtgga agtagaagat aaaaaagaag cagccgaaaa ggtagctgag attttggatg
     7321 aagattataa agatatttac gctttaataa gcaaaaaaaa tatggctctt gtaaaagtaa
     7381 aaagatggat agatgatgat aaggcaagtc aaataagaga tgctaaatta agtggaatat
     7441 gggtggcaga agataatcaa agatattacc catatgggaa ttttgcacca tatgtgttag
     7501 gacatacttc ttcagatgca acaggtatat ctggtgtaga aatgcaatat gataaaaagt
     7561 taaaaggaaa gcctggaaaa cttatagtaa gtactgatgc ttcaggaaga gaaataccac
     7621 aaggaatgga aaaatattat gagcctgtac aaggtaatgg tcttgtgttg tctatagatg
     7681 aagtaattca acactatact gaaaaagcag tacagaaagc ttatgagtta aataatgcaa
     7741 aaaaggttac tgcaatagct atgaacccta aaacaggtga tatacttgct ttagcatcaa
     7801 aaccagatta tgaccctaat gactcaagaa cgccaatata tccatattat caagaagaac
     7861 ttgaaaaata taatgataaa gataaaataa aaggctatta tcaaatgtgg agaaatccag
     7921 cagtaagtga tacatatgaa ccaggttcta catttaagct tattacatct tccagtgctc
     7981 ttgaagaagg agtaattaaa gatggagaaa aattcacatg tacaggtagt gtaactgttg
     8041 gaggaagaaa gattaaatgt tggagacatt acagacctca tggaacacaa gaatttaaac
     8101 aagcagtaca aaactcttgc aacccagtat ttgttgagtt gggaagcaga ttaggtgttg
     8161 gaaaaatgta tgattatata gaatcatttg gtcttatgga taagacaggt atagatttac
     8221 caggagaagc taagggaata ctgtataacg aaaaaaatgt aggaccagtt gaattggcta
     8281 caatatcatt tggtcaatct atatcagtaa ctccaataca acttataaca gctatatcat
     8341 caatagctaa tggtggagat ttaatgcaac caagagtggt aaaatcttat actgacaata
     8401 aaggaaatat aactgaaaca gtaaaaccaa aaaaagtaag aagtgttata tctaaagaaa
     8461 catctaaaaa aatgttagaa attgcagaat cagttgtaac tgaaggtgga ggaaagatag
     8521 catatatacc aggttataga cttggtggta aaacaggtac agctcaaaaa gttatagatg
     8581 gtaagtatgc tccaggaaaa tatatatgtt catttgttgg aatagcacct tgtgatgacc
     8641 cgcaaatagt agttcttgct attgttgacg aaccaacagg agtaagtgca tttggtagta
     8701 ctacagcagg accaatagtg aaagaaataa tgaatgactc tttaaaatat ttgggagtta
     8761 aaccagtata taaagaagaa gaaaaagctg agtatgaaaa gaagcaagtt aaagtgccag
     8821 atgtaagaaa tctaaaaata ggagatgctg taaaggcatt ggaggatgcg aagttaaaac
     8881 cagacttaga tgcagatata gaacttccag aagatacaaa ggtaaaggat atattcccaa
     8941 aacctggagt aaaagttaat gaagactcaa gtataaccct atattttgaa aactaaaaag
     9001 taacagataa ttaacatata cccataaaca tcttcaaaaa aacagaaata tagtatataa
     9061 ttataaagtt aagagttatc gtaggcaatg tatatataac ggtatacatt gccttttgtt
     9121 gctaagagaa tatagctaag gttttaaagg aggagtttaa taatggagtg cttaacaata
     9181 aaagagttag tacttgcaac taatgggaag ttaatatatg gagattataa tgactgtgta
     9241 agtgatatag ttatagatag cagggaggca aatgcccaaa atgcatttgt agccatagtt
     9301 ggagaaaatt tagatgggca tacatttatg aagtctgcat atgatagtgg atgtaaaact
     9361 tttataaaaa atgaaagtaa tggaataaaa ttagaaagtt cggatataaa tttaatagag
     9421 gtaaaagata catctttggc tctaggagat atttcaaaat actataaaga aaaatttgat
     9481 attccattta taggtgttac aggtagtgtg ggaaaaacta ctactagaga tatgatttac
     9541 tctgccatat ctgcaaagtt aaatatacta aaaaatgaaa aaaacttaaa taatcatttt
     9601 ggagttccat tgactttatt taatctaaat aaagaacatg agtgtgctgt aatagagatg
     9661 ggtatgtctg gattcaatga aataaaatat ttagtggata tagtaaatcc taaaattgca
     9721 gtcatatcga atataggatt atcacatgta gaaaaactag gttcacaaga gggtattttg
     9781 aaagcaaaga tggagattac ttcaaacttt gatgaaacaa atactttaat tgtaaatgga
     9841 gatgataagt ttttatctac attaaaagaa aaagaacatg tatataagtt aaaaacattt
     9901 ggctttaata aaaacaatga tgtttattgt gaaagttata ctatggaaga ggatagttta
     9961 acatttatat gtgtaataaa tgggaaaaaa gaggaaatat ttataccaac aataggagaa
    10021 cataatatat ataatgcaat gtctgctata ttagttggtt tgtgtctaaa tatttcttta
    10081 gattatataa aaaaaggttt aaaaaatttt aaagggacaa aaatgagatt agacataata
    10141 aaaaatgaaa aattaacaat aattaatgat tcatataatg ctagtccaga ttctatggat
    10201 gctgctttaa agatacttgg aagatataaa ggtagaaggg tagcgatact tggagatata
    10261 ctagaaatgg gtgaaatttc agagtatggt catagattag ttggaaaatc atctatgaat
    10321 aatactgata ttataataac tataggtgaa aattcagtgt ttattggaga agaagcaaaa
    10381 caattaggat tcaattcagc caatatatat cactttgaga atagagaaga tgtgtttaac
    10441 aagttaaatg aattagtaaa aacaggagac actattttag taaaaggctc aagaggcatg
    10501 agattagaaa aaatagtcga atatctaaat aaataagctt aaactaatga gttaattgac
    10561 aagggagagg agttttatga tgttaggaat aacagagctt acgtacaccg cattgattgc
    10621 gtttttaata gtaattataa taggaccaat atttatacca atgcttagaa aatttaaatt
    10681 tggtcagaca gttagagatg atggacccca aacacatcta gctaaaaacg gaacacctac
    10741 tatgggtgga attataatga ttgttgcaat tctaataact ggacttacaa gagtaaaagt
    10801 tagtcatgat atggcagtag gtcttatatg tattgcaggt tttggtttta ttggcttttt
    10861 agatgatttt ataaaaataa agctaaaaag atcacttgga ctaaaagcat atcaaaaaat
    10921 aatccttcaa gttgcattat ctttttatgt tgctttttat cagtatacat catcatcaag
    10981 tgcttcacaa cttatgatac catttacaga ttttgtgata aatgttggaa tattatatat
    11041 accaataatg atgtttataa tcgtagcaat agtaaatgct gtaaacttga ctgatggatt
    11101 agatggatta gcatcaggag taacattaat agtttctgta ttctttatgc tatttgcaag
    11161 ttctattgct ggaaatacag aagtcgcagt tttagcagca gcaactgttg gagcatgttt
    11221 aggtttctta ggatttaatt catatccggc tagagtgttt atgggcgaca caggttcaat
    11281 ggcattagga ggtgcagttg tagcattttc agttctaact aactcagtgc ttataatacc
    11341 tataattgga ggaatttatt ttgcggaggc tctatcagtt ttgattcaag ttggatattt
    11401 taaggcaaca agaaagagat tctttaagat ggctccaata caccaccact ttgaacagtg
    11461 tggttggcca gaaacaagag ttgtatttat tttttggatt ataacagttg ttttagcttg
    11521 gataagtata atagcagtat tttagggcta gggggaatga aaaatggact taaaaggaaa
    11581 aaaagtttta ttagtaggac ttgcaaaaac tggtatatct acaattaaac atttagataa
    11641 attgggtgca agtgtaatcg taaatgatat aaaagatgaa aataaattga gaaatatact
    11701 tgatgaattg aaatctataa atgacataaa atacatatta ggacatcacc cagaagatgt
    11761 agatgatata gatatggttg tagtgtctcc aggtgtacca ctagacctac cattcatatt
    11821 gaaattaaaa aattcaggca agtatataat tggtgaggta gaattagctt ttaaactatc
    11881 gaataatcca atttttatag ggattacagg tacaaatgga aagacaacta caactagttt
    11941 ggtaggagaa attttttcaa gagcaaaacg agatacatat gtagttggta atataggaaa
    12001 tcctgtaata gatactatag aaacttcaag tgaagagtct gtgttagtaa ctgaactaag
    12061 cagttttcag cttgagagta tagatgaatt tagacctaaa gtaagcgcaa tattaaatat
    12121 tacagaggac catttaaata gacaccatac tatggaaaaa tacatagaag caaaggcaaa
    12181 tatatttatg aaccaaactg ttgaggattt ctgtgtatta aactatgatg atgagatagt
    12241 aaaatcttta gctgataaat gcaatgccaa agtaatttac ttttcaagaa ctaaaaaagt
    12301 aaatggagga gtatatttag aaaataatga cataataata gatatagatg ataaaatcaa
    12361 atttctaaat aaagatgatg taagtttacc tggaggtcat aacttagaaa attgtatggc
    12421 agctatagca atagcatatg tctgcaaaat tgatttagaa gttataaagg atgtacttat
    12481 gacatttaaa ggagtggaac acagacaaga gtttgtaaga aatttagaca atgtaatata
    12541 tgtaaatgat tcaaagggaa ctaatccaga ttccactata aaagctatac agtcttatga
    12601 tagacctata atacttatag caggggggat ggataaggga agtaattttg atgaacttct
    12661 tgaaactgca aagtcatatg ttaaatcatt ggtcttatta ggagaaactg catcaaatat
    12721 agaaaattgt gctaaaaata aaggatttaa tgacatacat atagtaaaag atatggaaga
    12781 agcagttaag acttcttatg aaatttcaaa aagtggagat atagtgcttc tttcaccagc
    12841 ttgtgcaagt tgggatatgt atgaaagttt tgaagtaaga ggaaaagact tcaaagataa
    12901 tgtaaacaat ttaaaataat ctcttacctc taaacttact taaatggaag aatggaggta
    12961 gattagttgg atgcctaaag aaaatttgaa aaaacaaatt gacataagga tgaagactga
    13021 atttgatgga gtagtgtttt acactactat gcttttagta tttgtaggaa tagttatggt
    13081 gtttagtgca agttttatac aatcttcatt taaacacaat gatgcgtact attttctaaa
    13141 aaagaatgta atatatgctg tacttggatt tatagttatg attattacat caagaataga
    13201 ttatagtttt tggaagaaaa atgctacagc aattggagct atagcagtag tattattatt
    13261 gttagttttg acccctttag ggatagaagc aaacggagca aaaagatggt tgggaatagg
    13321 agctttaaca tttcaacctg cagaaatcgc aaagtttgct acaataatat taactgcaaa
    13381 attaattgaa aaaaattatg ataaaataaa atctttgaca aaaggtgttg taccacttct
    13441 cgtagttcca gggatatttt ttgcgttgat aatacttcag ccaaatttgt caacagcagg
    13501 tactgtaatt ctagttactt ttgtaatgat atttgttgct ggaatggata tgaaaattgt
    13561 atttgctatg atagggagtg gggctgcttt atttgctgca ttagtaattg ctgaacccta
    13621 tagacttagt cgtgttacat catttttaga cccttttcaa gaccctcttg gtaaggggta
    13681 tcaggtaata caaggtctat atgcactagg ttcaggtgga ttgtttggtc taggcttagg
    13741 aaagagtaaa caaaagtatt tttatatacc agagccacaa aatgacttta tatttgctat
    13801 aataggagaa gagttaggat tgattggttg tataatagtt attatgctat ttgtagtttt
    13861 agtctacaga tgtgtaagaa tagctttgaa gacttctaat gtatttgctt gtatggttgt
    13921 tataggtata ggtgcacaaa ttggaataca agcagcttta aatatagcag ttgcgacatc
    13981 atcaatgcca gctacaggtg tagcactacc atttataagt tatggaggaa cttcactcac
    14041 catctttatg ggagctgtag gaatagtgtt aaacatctca aagcatgtca aaattaatta
    14101 acaggagatg atgatttgat gaaagtttta ttatcaggcg gtggaactgg agggcacgtg
    14161 tatccagcta tagctattgc aaacaaaata agagatgagc atccagacgc tgagataatt
    14221 tttgttggga cggaaaaggg aatagagtca gaaatagttc ctaagtatgg atttgaatta
    14281 aagactgtaa cagttcaagg ctttaagcga aaaatagatt tcgataatgt aaaaagagtt
    14341 tttaagcttt ttaaaggttt ggagcaatca agaaagattg ttaagaaatt taaaccagat
    14401 atagttatag gaactggtgg atatgttagt ggacctgttt tatttaatgc atctatgggg
    14461 aaaataccag ccataataca tgagcaaaat tcttttcctg gtgtaactaa taagatttta
    14521 tctaaaacag ttacaaaggt acttacaagt tttgaagatt cgcataaaag atttccagag
    14581 gcagcagaag ataaattagt ttttacagga aatccagtta gaaaagaaat tttattatca
    14641 agaaaaaata ttgcaagaaa gaatctatca ataagtgacg aaaaaagaat ggtactttgc
    14701 tatggtggta gtggaggttc aagaaaaata aatgatgcaa tgagacttgt aataaagaat
    14761 atggtaaatg aagatatagc ttttatattt gctacaggca aaagctatta tgatgaattt
    14821 atgggaagta ttagcgatat aaatcttaaa ccataccaaa aagttgtgcc ttacttagaa
    14881 gatatggcaa atgcacttgc agcaagtgat ttggttatag gtagcgcagg agcaatttca
    14941 ttagctgaga taacggctct tggaaagcca tctataataa tacctaaagc ttatactgct
    15001 gaaaatcatc aagagtataa tgccaagagt atagaaaaac aaggggcagg aattgctatt
    15061 ttagaaaaaa atctaactcc agagagccta aatacagcag tatttaaact tttaggagat
    15121 agagaacttt tggttgatat ggcaaatgca agtaaaacta taggtaagcc tgaagccata
    15181 gaccttatat atgatgagat aatgaaagta tacaattcaa cacaaaagtc aacttctaaa
    15241 aaaacaaaaa aagaaaaagt tattaaggaa gtaaaagaaa taaaaaaaga aacgactcca
    15301 agtatagaag gtcaagctaa ggtaatagga ataaagaaaa gataagtaaa tatttacccc
    15361 taatttataa tatattagat tttctaaatt attataaatt aggggtttat ttgtatgt
//
LOCUS       DAJMZY010000099        14906 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.100, whole genome shotgun sequence.
ACCESSION   DAJMZY010000099 DAJMZY010000000
VERSION     DAJMZY010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 14906)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14906)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14906
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.100"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            40..678
                     /locus_tag="OE968_002954"
     CDS             40..678
                     /locus_tag="OE968_002954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220215.1"
                     /translation="MSNQRKDFDITNDMFQESIPITTKIILEDMPSNDELNHVFSKGC
                     ERKMKKRKIVLITLLLIGVLLLGSILYNLFLGKTANISMLKESWNFDIPIPNKEIEVF
                     DTQDSINGDGQSYFIQGFSEKNFKKVFNLKGGIVVSKDNINEIEKYIDKFKRDSVNIN
                     KSNKNKIEEDFKKYKLEVKKDDKYIYKRNYENYVVLIIKKDEQKLYSLIWNQ"
     gene            complement(1167..2927)
                     /locus_tag="OE968_002955"
     CDS             complement(1167..2927)
                     /locus_tag="OE968_002955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HCP7220216.1"
                     /translation="MQEVEVIKAKNVLARQARGKAIERLRVAAYCRVSTDSEDQLNSY
                     KSQVQYYTDMIKKNKEWVLADIYADEAITGTQVTKREDFQRMINDCMNGEIDMVFTKS
                     ISRFARNTLDTLKYVRMLKERNIAVYFEDEKINTLTMDGELLLVVLSSVAQQEVENIS
                     ANVKKGLKMKMKRGELVGFQGCIGYDYHPEDKTITVNQEEAEIVRYIFNRYVDGAGGS
                     VIGQELESLGYKTKYGSSTWAPSTVIGIIKNEKYKGDILLGKTFTVDPISKRRLENMG
                     EEDKFYMKDHHEPIISEEVFEKAQEILNRRNKNRTTVGSGKREKYSRKYAFSCMLECG
                     FCGGTLTRRNWHSGSKYSKVIWQCVTATKKGKKFCKHSKGIPETAIEEAFVESYRLLC
                     DDNKDVLEEFLQRMDDTLSSSVVSKQLAKAEKEIDALEKKKSKLVDMRLEEIIDKETY
                     ESKYADLVSKQEQLVEERQKLQETSDNEKDIKKRLKEFKKTLEQNEVLDKFDRYVFES
                     IVEKVIVGGLDENGNVDPAQLTFVYKTGLKNSVDGAKFKTQRKNARGRHRTNELCSHD
                     SNEVDKMCSDSSNDTCGNCS"
     gene            complement(2990..3133)
                     /locus_tag="OE968_002956"
     CDS             complement(2990..3133)
                     /locus_tag="OE968_002956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HCP7220217.1"
                     /translation="MNNIIRYSMQIAMLKQLLARKLISEKEYTLVKQRLMKDYKVLSD
                     ITA"
     gene            complement(3452..3691)
                     /locus_tag="OE968_002957"
     CDS             complement(3452..3691)
                     /locus_tag="OE968_002957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002592280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCP7220218.1"
                     /translation="MMKSTKKCPSFSTISSAADGNEVAIEKILNHYDAYISKASLRPF
                     YDEHGNMYIVLDMELKGRIRAALIKVILGFEVKVK"
     gene            complement(3696..4112)
                     /locus_tag="OE968_002958"
     CDS             complement(3696..4112)
                     /locus_tag="OE968_002958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002592281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HCP7220219.1"
                     /translation="MKPSSFEGAIRLQFDCLARKVVGRTVKNYDRELGRRARRETPFC
                     DLSEMELNQIGAMDEYCVEFTSFDVFGSEVHIYDERLCEAIKELTESRRNILLMSYFL
                     EMTDAEIAEVMEMERFSVCRNRLHTLKLIKDMYEEE"
     gene            complement(4109..4408)
                     /locus_tag="OE968_002959"
     CDS             complement(4109..4408)
                     /locus_tag="OE968_002959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HCP7220220.1"
                     /translation="MKHLHIQQLSTIGSSLKKHLNSTEHNAPICGFLQHITGIICLAQ
                     DQYVCIALVLFYCIKLFQKIFAVGYQIPPFMVSVSAKRGRSLFALATFAGKGVRL"
     gene            complement(5459..5626)
                     /locus_tag="OE968_002960"
     CDS             complement(5459..5626)
                     /locus_tag="OE968_002960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002587909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220221.1"
                     /translation="MNWKELWMTLFGTTEWLGLNIGFWVAMAVVLLIVIVMNVVFWSM
                     KPKKDTKESYK"
     gene            complement(5639..8404)
                     /gene="mgtA"
                     /locus_tag="OE968_002961"
     CDS             complement(5639..8404)
                     /gene="mgtA"
                     /locus_tag="OE968_002961"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002571344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HCP7220222.1"
                     /translation="MNKKENRMAIRQTVEKAVIRDEQNRRIQFAATNPIKEVLKKLHT
                     TLRGLEVDEVSVSRAKYGTNKVTHEKKKSLAKRLVGAFINPFTAILFCLALVSTITDM
                     IFPYFSLFGSVPEDFDSLTVVIILTMVFISGTLRFVQESRSGNAAEKLLAMITTTCTV
                     TRRNYEKKELPMDDLVVGDIVHLSAGDMIPADVRILDAKDLFVSQASLTGESEPIEKT
                     PNVSAQKESVTDYTNIAFMGSNVISGSATAVVVCVGDHTLFGSMASAVAGEAVETSFT
                     KGVNAVSWVLIRFMLIMVPLVFFVNGITKGDWLAAFLFGVSIAVGLTPEMLPMIVTTC
                     LAKGAVSMSKKQTIVKNLNSIQNFGAIDILCTDKTGTLTQDKVVLEYHLNVNGEDDTR
                     VLRHAYLNSYFQTGYKNLMDLAIIHKTEEEEAADSRLIDLSENYVKVDEIPFDFTRRR
                     LTTVVQDNKGKTQMVTKGAVEEMLSICAFAECNGGVQPLTDDVRYRILETVDNLNDKG
                     FRVLAIAQKSNPSPIGAFGVKDECDMVLIGYLAFLDPPKESTADAIKALKDHGVITKI
                     LTGDNDKVTRTICKQVGLEVRNMLLGSDLEQMGDAELARVAESTDVFAKLTPDQKARV
                     VSVLRENGHTVGFMGDGINDAAAMKAADIGISVDTAVDVAKESADIILLEKDLMVLEQ
                     GIIEGRKTYANMIKYIKMTASSNFGNMFSVLAASALLPFLPMMSVHLIFLNLIYDLSC
                     TAIPWDNVDEEFITKPRKWDASSVGSFMIWIGPTSSIFDFTTYIFMYFVFCPLFVSNG
                     VLFNDLPAHFSGAELAMLQAQYIGMFQAGWFVESMWSQTLVIHMIRTPKLPFVQSRAS
                     APVTLLTMTGIIVLTIIPFTVFGTMLGFVALPAAYFAYLIPCILLYMTLATSLKKAYV
                     RHFGELL"
     gene            complement(8570..8881)
                     /locus_tag="OE968_002962"
     CDS             complement(8570..8881)
                     /locus_tag="OE968_002962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3784 domain-containing protein"
                     /protein_id="HCP7220223.1"
                     /translation="MDFTCIFFGILFTLAGFWLAFGKGYRHLSLWKNMPQEEKDKINI
                     VPLCRNVGEMIALNGIIFLMKGFLPGFSNHWFVFAIIAWLIVAGFDVWYIEKSVRYRN
                     Q"
     gene            complement(9128..9805)
                     /locus_tag="OE968_002963"
     CDS             complement(9128..9805)
                     /locus_tag="OE968_002963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018597221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HCP7220224.1"
                     /translation="MFYTDFILRIALSLTLGFLIGLERQLTGHPAGIRINVLICMGTS
                     FFTLFPMLYGSDQVFRVGSSIISGVGFLCSGVIFKDRGTVRGMNTAATLWCTAAIGIL
                     ASTGMYAMAITAATILIGSNLILRPFARKFHPITSSDESEKQYRISVTCQEKAEQDIR
                     LLLINSNSCKTLFLNNLESGDVVGDKVEIVAEYCSVGKSKNNILEGIVGQVLVIPEVI
                     SAGWEVL"
     gene            complement(9943..10446)
                     /locus_tag="OE968_002964"
     CDS             complement(9943..10446)
                     /locus_tag="OE968_002964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006566797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HCP7220225.1"
                     /translation="MKKNISYIPMDSALEIWLLEKLLRDPPDSDCAKDLLSGIQEMIR
                     GEVSSLLLGASEESDWPVGTLSDRILAGDLEIYPRGRKVLIKGSEVNLTPKEFDILYF
                     LVQNKGEVFTKEQIYRAVWEEDYILDNSNIMAFIRKLRKKIEPAPDCPTYILTIWGIG
                     YKFNDQI"
     gene            complement(10462..13125)
                     /gene="mgtA"
                     /locus_tag="OE968_002965"
     CDS             complement(10462..13125)
                     /gene="mgtA"
                     /locus_tag="OE968_002965"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016440611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HCP7220226.1"
                     /translation="MSKATLFDSRIKKYAYCRTSEIYRDIGSSPDGLSIEQIGSMREK
                     YGANSFNGRKNDTTMQRLRRAFINPFHVILFVLGIVSLVTDVFVASNFARNATTAIII
                     FSMIVISGVIRLIQELRAKSAAAQLDRLVHESVTVRRDGKLIEIPGEELVVGDIVLFS
                     AGDRVPADIRLTKITDLFISQAAITGESAIIEKSCRKLSYGEQDTLTQLENLAFMATT
                     VISGKGEGIVLAVGKDTLYGGFTKPDSDDKNSFKKGADSIAWVMIRFMAILVPIVFIL
                     LGITDGKWMESFAFALSVAVGLMPEMLPMVITACLAKGSLAMSKKQTIIKDINAMQSF
                     GSMDVLCMDKTGTLTNESILLEYYMDIFGNENAEVLDLAYLNSCYHSGVCNTIDNAIL
                     ACNTMPGREAHYANLLTKFQKADEIPFDYARKFVSTLVQDSNGNSQLIMKGDIEHIFS
                     RCNHVEYRGKLLPMGQDARQSVSSVVGEMLQDGMKVIAVARKNVGAQKKITPDDEWGM
                     TLVGYLSFFDAPKQTAKESVTALKRLKVIPKILTGDQAAIAVSVCRRVGIYTERILTG
                     TQLDEMTDCELKKAVEHTHVFAELTPGHKVRLVSAMQDNGHSVGFLGDGVNDIPALNE
                     ANVGISVDTAVDAAKDAADVVLLQKDLNVLEQGVMEGRKTFTNMLKYIKITASSNFGN
                     IFSIICASAFLPFLPMTSIQILLLNLLYDTLCIVLPWDNVDEEEMLSPRDWSGKTLRQ
                     FMLSFGPISSLFDIVTFLFLYYFLCPMLCGGATYLQLTDPSLQLQYVALFQTGWFLES
                     MWTQVLILHFLRTSKIPFFQSRASAPVISITLVGIIAFTSLTFVGGASLFGLTKLPLW
                     YFVFLLLVVSLYMLLNSVAKYFYKKKYQELI"
     gene            complement(13218..13427)
                     /locus_tag="OE968_002966"
     CDS             complement(13218..13427)
                     /locus_tag="OE968_002966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220227.1"
                     /translation="MVKVKTKKKFVSTHMCQGEMPIYVRERYEKMLAVSIRAPNLEGM
                     VENFDKDLSRPNETDLIELKNAISK"
     gene            13377..13712
                     /locus_tag="OE968_002967"
     CDS             13377..13712
                     /locus_tag="OE968_002967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220228.1"
                     /translation="MTHMSADKLLLGFHLDHVSNLNELLRKVAHNNICIMSDRMTKVA
                     VWKPSVKTIQLVCMEYLNYIIDHSVIYEKIQCANWNGTEETNSIFNNSPSPLITLIYS
                     CDLQQNKTT"
     gene            complement(13911..14813)
                     /locus_tag="OE968_002968"
     CDS             complement(13911..14813)
                     /locus_tag="OE968_002968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HCP7220229.1"
                     /translation="MFKKNKKQTENVKEKKVRTVKVGTHKKTVIALWVVLIASVSFGV
                     YKNFTAIDQHTTHEKEVIELRLQDTNGIENFVKNFAKSYYTWSNSKEAIDARTQAISG
                     YLTKELQDLNMDTIRTDIPTSSAITDVIVWSIEQSGTDTFSATYEVDQQIKEGEQTTA
                     VKATYTVKVHVDAGGNMVIIQNPTLAPAIEKSDYEPKTPEADASVDADTINDATAFLE
                     TFFKLYPTATEKELAYYVSGNVLESIGRDYLYSELVNPIFTVDGDNVKVKVAVKFIDN
                     QTKATQVSQFELVLHKESNWKIIG"
BASE COUNT         4685 a         3188 c         2430 g         4603 t
ORIGIN      
        1 actagaaaaa atcaaaagaa atattagaag aaatggatat tgagtaatca aagaaaagat
       61 tttgatatta caaatgatat gtttcaagaa agcattccta tcacaacaaa aattattctt
      121 gaagacatgc cttcaaatga tgaattaaat catgtttttt caaaaggttg tgaacgaaaa
      181 atgaaaaaga gaaaaattgt attaatcaca ctactattaa taggtgtttt gttattagga
      241 agtatcctat ataatctttt tttaggaaaa acagctaata tttcaatgct aaaggaatct
      301 tggaattttg atataccaat acctaacaaa gaaattgaag tatttgatac tcaagatagt
      361 attaatggag atggacaaag ttattttatt caaggatttt ctgaaaaaaa tttcaaaaaa
      421 gtttttaatt taaaaggtgg tatagttgta agcaaagata atattaatga aatagaaaaa
      481 tatattgata aatttaaaag agattctgtt aacattaata aaagtaataa aaataaaatt
      541 gaagaagatt ttaaaaaata taagttagaa gttaaaaaag atgataagta tatatataag
      601 agaaattatg agaactacgt agttttaatt ataaaaaaag atgaacaaaa attatacagt
      661 ttaatatgga atcagtaggt acatatgtat tattaagaat tataaataat aaaaataaat
      721 tttagtcaat atacaaaaac cttttaaatt gtctggaaat cacctcttca tttgttataa
      781 aaacatacaa caaatgaaga ggtgatttta tggttttaaa aaaaataatt ataagtggat
      841 atgtgctttc acatgtttat caacatttgt aatgcctata tttgctaatg aattataaaa
      901 atattaaata atattcaact atagattatg taaattactc tatgaaaaaa atgagttgta
      961 taaaatctgg ctactgtaga ttgactattt cttttaaaat tacaattata ataagtttta
     1021 tagaattaaa aataaaactt tagagatttt tgataacatt gtagactaaa tttgccaccg
     1081 aaatcgcttt acagtggcaa atcggtggca aatacaatat attattagta tataatctat
     1141 ataaacatta ctattgtttg attatcttag ctacagtttc cacatgtgtc gttactacta
     1201 tcggaacaca ttttatcaac ctcgttgctg tcatgtgaac acaattcatt agtcctatgc
     1261 cgtcctcttg catttttcct ttgtgtttta aatttagcac catctacgct attcttcaag
     1321 cctgttttat aaacaaaggt caactgtgca gggtcaacat ttccgttttc atcaagtcca
     1381 cctacaatta ctttttcaac aatgctttca aacacatagc ggtcaaattt atcaagaacc
     1441 tcattctgtt ccagagtttt cttaaactct ttcaaacgtt tttttatgtc tttctcatta
     1501 tcagaagttt cttgtaactt ttgtctttct tcaacaagct gttcttgttt acttactaaa
     1561 tcagcatatt tactttcgta ggtttcctta tcaataattt cttccagacg catatccaca
     1621 agtttacttt ttttcttctc taatgcgtct atctcctttt ccgcttttgc aagttgtttt
     1681 gacaccacac tactactaag agtatcgtcc attctctgca aaaattcttc cagaacatct
     1741 ttattatcat cacataataa acgataactt tctacaaatg cttcttcaat agctgtttct
     1801 ggaatacctt tgctatgttt acaaaatttc tttcctttct tcgtagccgt tacacattgc
     1861 catataacct tgctgtattt tgagccactg tgccaattac gtcttgttaa agtaccacca
     1921 caaaagccac attctagcat acagctaaat gcgtatttcc tgctatactt ctcacgctta
     1981 ccgctgccta ccgttgttcg gttcttattt ctccgattaa gaatttcctg tgctttttca
     2041 aaaacttctt cactaataat cggctcatgg tgatctttca tataaaattt atcttcttca
     2101 cccatgtttt caaggcgacg tttggaaatc ggatcaacag taaaagtttt gcctaagagt
     2161 atatcaccct tgtatttctc attcttaata attccaataa ccgtagatgg tgcccatgtg
     2221 gaactcccat acttcgtttt ataacctaga ctttcaagct cctgtccaat aacagaacca
     2281 ccagcaccat caacataacg gttgaaaata tatctgacaa tctctgcttc ttcttgattt
     2341 acagttattg tcttatcctc tgggtgataa tcatatccaa tacaaccttg aaaacctacc
     2401 agctcgccgc gcttcatttt cattttcaac ccttttttta cattggctga aatgttctcg
     2461 acttcctgct gtgcaacaga actaagaaca acaagcaata actctccatc cattgtaagt
     2521 gtattgattt tttcatcttc aaaataaacg gcgatatttc tctcttttag catacgaaca
     2581 tatttcaatg tgtctaaagt atttctggca aatcttgata tggattttgt aaataccatg
     2641 tcaatttcac cattcataca gtcatttatc atacgctgaa aatcttctcg ttttgttact
     2701 tgtgtccccg taattgcttc atcagcataa atgtcagcta acacccattc cttgtttttc
     2761 ttaatcatgt cagtataata ctgaacttgt gatttataac tgtttaactg atcttcgcta
     2821 tctgtactta cacggcaata tgcagctaca cgcaaacgct caatggcttt tccacgggct
     2881 tgtcttgcca aaacattttt tgcttttatt acttcaactt cctgcatagt acacctcctt
     2941 attttgtgtt cctttcatat tgttattgta ctactttaaa aaacacaatt caagcagtta
     3001 tgtcagaaag caccttatag tctttcatca gcctttgttt tacaagagtg tattcttttt
     3061 cagaaatcag tttacgggca agcagttgtt ttaacatagc aatttgcata ctatacctaa
     3121 ttatattatt cattaaaacc ctccttgctt ttttatttat ggaagtaatc agacggcttc
     3181 ggcagctcca ctggactttc accattccca ttctgatggg tgaaccgtgt catacgggtg
     3241 tatcattatt cagatatacg agtcatggca gcaacctttc caaagatcgc ttgcggttca
     3301 ctggcataat cgctcgctgc tttccccatt tcagtggtcg tggcgttcca gtccgctggc
     3361 tcgtcgtata tcaaacgtat ctgattactg tattcacttg tcaaagaacg gaaaagagtt
     3421 aaaatgaggt ggtagatact ctctgttata tttacttcac tttgacttca aaccctaaga
     3481 ttactttaat caacgctgcc cgtatcctgc ctttcagttc catatcaagc acgatataca
     3541 tattcccgtg ttcgtcatag aacgggcgta ggctggcttt tgatatgtaa gcgtcataat
     3601 ggttcaaaat cttttcaatt gccacctcgt taccgtcagc tgcagaactg atggtcgaga
     3661 atgatggaca cttttttgta gacttcatca tgtttttatt cctcctcgta catatcctta
     3721 ataagcttta atgtgtgcag cctgtttcta catacggaaa atcgttccat ttccataacc
     3781 tctgcaattt cagcgtcggt catttcaaga aagtaggaca taagcagaat gttacgtcgg
     3841 ctttctgtta attctttgat agcttcacat aagcgttcat catagatatg gacttctgaa
     3901 ccaaatacat caaatgacgt aaactcaacg caatattcgt ccatggcacc gatctggttt
     3961 aactccattt cagataaatc acagaacggc gtttcacgtc ttgcacgtct gccaagctct
     4021 cggtcatagt tctttacagt tcgtcctaca accttgcgag ctagacaatc aaattgaagt
     4081 ctgatagcgc cctcgaaaga agatggtttc ataatctcac cccctttcca gcgaaagttg
     4141 ctaaagcgaa aagacttcta cctcttttcg cactaacact caccatgaaa ggtgggattt
     4201 gatacccaac cgcaaaaatt ttttgaaaaa gttttatgca gtaaaaaagc acaagggcaa
     4261 tacagacgta ctgatcttgt gctaaacaaa ttattcctgt tatatgctgt aaaaaaccac
     4321 atataggagc attatgttcc gtagaattta aatgtttttt taatgaacta ccgatggtcg
     4381 aaagttgttg aatatgtaag tgtttcatac ggctacccct agagccgata aaacaagacc
     4441 atccagtaat ttgtccaacg ttaggcaaaa ataaaacggc ggctatataa ccgtcgtctt
     4501 attcaaaagt tcaaaaagaa ctaaactaaa ccctctaaag cagtatgtat ttataatcag
     4561 tcttgcaaaa taacaaagta gaattgaaat ataaggtagc aatccttgtg catctaataa
     4621 acttataggg gttacagcag accacggaat aatattttgt atactttcag atcaatatag
     4681 tccaacaaaa ccaattcccg atatttagta actaaaaagt aaactagagt agaaaacatt
     4741 tctttgcaaa acacaaataa taagtaatgg actcattgac aatagattga gaaatccagt
     4801 tttttagact tagatagatt atctcacttg taaatgattt aagttctttg acttcatata
     4861 tagcggtata atctgtcaac gtgatcatta caaaccataa tgcctatata acatactttc
     4921 caagcaaaaa ctttattcta ttagttgggg aatacaaaat atttatcatt gtgcgttcaa
     4981 catattcttt ttgtataaaa atgtaattac aaaacaccac tcaatataag atagataata
     5041 atttgaatag gaattatcaa tctacgtaac cattcattac ctgtcattgt tgttacaata
     5101 gatttgggat tctgtttcca ttacataatt tttttatcct tctttcagat atctcctcat
     5161 tttatcgaag cttcttctac agacatacat tccataataa aatctacctt tgaatattat
     5221 ttcacgattt cgttatagac gcgtaaacaa acaataaaaa acgaaatttc ttttaagtac
     5281 cataattttt atatcgaaat tacaattatc cacttatata cagcatttat aggtaattca
     5341 atgataaaaa aacacatact ttactactaa attgccacaa ttgaatgcgc cttgatatga
     5401 tagggagatt ccacaataaa aaactgtgca tctcccttga ttcattcata ctgatatctt
     5461 atttataaga ctcttttgtg tctttttttg gtttcatgga ccaaaatact acattcatta
     5521 caataacaat cagcaacaca actgccatag ccacccaaaa gccgatatta agaccaagcc
     5581 attcggtagt tccaaaaagg gtcatccaaa gttctttcca gttcatcatt ccacctcctt
     5641 aaagcagttc tccgaaatga cggacatagg ctttttttaa acttgttgcc aaagtcatat
     5701 acagcagaat acatggaatc agataagcaa agtatgctgc aggcaatgca acaaatccaa
     5761 gcatagttcc aaacacagta aacggaataa tggtcagaac tataattcca gtcattgtta
     5821 gcaaagtcac cggagctgat gcacgactct gaacaaaagg tagctttgga gtacgaatca
     5881 tgtgaatgac taatgtctgg ctccacatag attccacgaa ccaccctgct tggaacatcc
     5941 cgatatactg tgcctgaagc attgccagtt ctgcaccgct gaaatgagca ggcaaatcat
     6001 taaataatac accattcgat acgaacaatg gacaaaatac aaagtacata aaaatatagg
     6061 ttgtaaaatc aaagatagaa ctggttggtc caatccagat cataaaactt ccaacactgg
     6121 aagcgtccca tttacgaggt ttggtaataa actcctcatc cacattatcc caaggaattg
     6181 cagtacagga taaatcataa attaagttta gaaatataag atgaacactc atcattggta
     6241 agaaaggtag caaagcagat gcagcaagca ctgagaacat attgccgaag ttggatgaag
     6301 cagtcatttt aatgtacttg atcatgttgg catatgtctt tcgtccctca ataataccct
     6361 gttccaaaac catcagatct ttttccaata gaataatgtc agcagattct tttgccacgt
     6421 ccacggcggt atccaccgaa ataccaatat cggcggcttt catagctgca gcatcattaa
     6481 taccgtcacc catgaaaccg accgtatgac cattttcacg gagaacagaa accacacggg
     6541 ctttctgatc aggggttagc tttgcaaata catctgtaga ctctgccact cttgcaagct
     6601 ctgcatcgcc catttgttcc aaatcagaac cgagaagcat attgcgaacc tctaatccca
     6661 cctgcttgca gatagttcga gtcactttgt cgttgtcacc tgtcaaaatt ttggttataa
     6721 caccatggtc tttcagagct ttaatagcat ccgcagtaga ttcttttgga ggatcaagga
     6781 atgccagata tccaatcagt accatatcac actcatcttt aacaccaaat gcgccgattg
     6841 gggaaggatt actcttctgt gcaatagcta gtacgcggaa tcccttatcg ttaagattgt
     6901 ccactgtctc cagaattctg taacgaacgt catcagtcag aggctgcact cctccattac
     6961 actctgcaaa cgcacaaata gagagcattt cttccacagc accttttgtt accatctggg
     7021 tcttaccctt attatcctgt accactgtag tcagacgacg acgtgtgaag tcaaaaggaa
     7081 tctcatctac tttcacatag ttttcagaca ggtcaatgag acgcgaatct gcggcttcct
     7141 cttcctccgt cttatggata attgccaaat ccatcaggtt tttatagcca gtctggaagt
     7201 aactattgag gtaagcgtga cgcagtactc gcgtatcgtc ctcgccattt acattcagat
     7261 ggtattccag cacaacctta tcctgggtca gcgtgccagt cttgtcagta cagagaatat
     7321 caatagcacc gaagttctga atggaattga ggtttttaac gattgtctgc ttcttgctca
     7381 tggaaacagc gcctttcgca agacaggttg ttacaatcat cggcaacatt tctggtgtca
     7441 aaccaacagc aatagaaacg ccgaataaga aggccgccaa ccaatcgccc ttggtgatac
     7501 cattgacaaa gaacaccagc ggaaccataa tgagcataaa acgaatcaat acccaagaaa
     7561 cggcattgac acccttggta aagcttgttt caaccgcttc tccagcaact gcggacgcca
     7621 tagagccaaa cagagtatga tcgccaacac aaacaacaac agctgttgcg ctaccagaaa
     7681 ttacattact ccccataaaa gcaatgtttg tgtaatcagt cacgctttct ttctgagcac
     7741 ttacattggg tgttttttca ataggttcac tctcaccagt aagacttgcc tgactgacaa
     7801 acaaatcctt cgcatccaaa atacgaacat ccgccggaat catatctcca gcagaaagat
     7861 gcacaatatc tcccaccacc aaatcatcca taggaagttc ttttttttca tagtttctac
     7921 gagtaactgt acaagtggtc gtaatcatgg ctaacaattt ctctgctgca tttccgcttc
     7981 tggattcctg tacaaaacga agcgtaccgg aaatgaatac cattgttaaa atgattacaa
     8041 cagtcaggga atcaaagtcc tctggcacac tgccaaacag agaaaaatac ggaaaaatca
     8101 tatctgtaat tgtggatact aaagccagac aaaataaaat ggcggtaaat ggattgataa
     8161 atgcgccaac cagtcgtttt gccagagatt tctttttttc atgagtgact ttattggtac
     8221 catatttagc acgacttacg gatacttcat ctacttctaa gccacgaagt gtggtatgaa
     8281 gtttttttaa aacttcttta ataggattgg ttgccgcaaa ttgaatgcgg cggttctgtt
     8341 cgtcacggat gactgctttt tctacagtct gacgaatagc catacgattt tcttttttgt
     8401 tcattggtct tacctccttg aattttcata ggggcaagga atattatatg agcgacacgg
     8461 aatctccaaa ttctcatata atattctctg ccttcgtgga ctgacatcag agtccatgtc
     8521 tttcacctca caatcttaaa aaaatatcta tgtgaaacct caatgtggat tattggttgc
     8581 gatagcggac acttttttcg atataccaga catcaaagcc ggcaacaatc agccatgcga
     8641 ttattgcaaa tacaaaccag tggtttgaaa atcccggcaa aaatcctttc attaagaata
     8701 taatcccatt taacgcaatc atttctccaa cattacgaca aagcgggaca atattaattt
     8761 tatctttctc ctcctgcggc atatttttcc acagggaaag atgacgatat ccttttccaa
     8821 aggccaacca aaagcctgca agagtaaata aaattccaaa aaagatacat gtaaaatcca
     8881 tcgtttgttc ctcctttcaa tgcttaaacc tgtttcttag ttttgtcagc ttcagaagtt
     8941 taatgaagag cacaataata gtaacagcaa gaataaacca gatcacaata ctcacctgat
     9001 accatatctt aaagattacc attctttgtt caaagaaatt ccaacccaaa tagctacata
     9061 agattgtaaa tacagggtag aaagcaaaaa gaattgctcg tttcaaatct tcgatttctc
     9121 tcctcactca caacacctcc caaccagcac taatcacttc cggaattacc aatacctgcc
     9181 caacgattcc ttctaaaata ttgtttttgg attttccgac agaacagtat tctgcgacaa
     9241 tctcaacctt gtcaccaacc acatcaccgc tttccagatt gttcaaaaag agcgtcttac
     9301 aggaattgct gttaatcagc aataagcgta tatcctgctc tgccttttcc tgacatgtaa
     9361 ccgaaatacg atactgcttt tcagattcat cactggaagt aattgggtga aactttcttg
     9421 caaagggacg tagaatcagg ttggaaccaa ttaaaatagt agcggcggtg atcgccattg
     9481 catacattcc cgtacttgca agaattccaa tcgctgcagt acaccataag gtggcagcgg
     9541 tattcattcc acgtactgtc cctctgtcct tgaaaataac accactgcat aaaaaaccaa
     9601 caccggatat aatactgctt ccgacacgga atacctgatc cgaaccgtag agcataggaa
     9661 acaaggtaaa gaaacttgta cccatgcaga ttaacacatt gatacgaata cctgcaggat
     9721 gaccagtcaa ttgccgttct aatccaataa gaaatccaag tgttaaggag agggcaattc
     9781 tcaaaataaa atctgtgtaa aacatatgaa acacctccct ttaactacta acagtatata
     9841 aaaaatccaa atacaatcct atggctaaag tcttgcgatt ttcttgcgat ttggtaagaa
     9901 aatagacgga ctgaaaccga aaatggtctt agtccgtctt tgtcatatct gatcattaaa
     9961 tttgtatcca ataccccaga tggtcaaaat atatgtggga caatccggag caggttcaat
    10021 cttttttcgc aacttccgga taaaagccat aatgttgctg ttatccagaa tataatcttc
    10081 ctcccatacg gcacgataaa tctgttcctt tgtaaaaact tcacctttgt tctggacaag
    10141 aaagtacaaa atatcaaatt cctttggagt caggttgact tcagaacctt ttatcagtac
    10201 ttttctgcct cttggataaa tttccagatc ccctgccagg attctatctg acagagtacc
    10261 cactggccaa tcgctttctt ctgatgctcc taacaataac gaagatacct ctccacgaat
    10321 catctcctga ataccagaaa gtaaatcctt cgcacaatca ctgtccggtg gatctcttag
    10381 tagtttttct aatagccaga tttcaagagc cgaatccatc ggaatataac taatattctt
    10441 tttcatcatg aatgcctcct cttaaatcaa ctcttgatat tttttcttat aaaaatattt
    10501 ggctactgaa ttcagcagca tatagagaga taccaccagc agtaaaaata cgaaatacca
    10561 aagaggtaat ttcgtcagtc caaacaacga cgcaccgccg acaaatgtaa gggaagtaaa
    10621 agcaataatc cccactagag ttatagaaat gaccggtgca gatgccctgc tctggaaaaa
    10681 aggaatcttg gaagttcgca gaaaatgtaa aatcaaaacc tgtgtccaca tagattccaa
    10741 aaaccatcca gtctgaaaca gtgctacata ctgaagttgc agggaaggat ctgtaagctg
    10801 cagataggtt gcccctccac atagcatcgg acataggaaa taatacaaaa ataggaaggt
    10861 gacaatatca aacagagaac tgatcggtcc gaaagacagc ataaactgtc tcagtgtttt
    10921 gccggaccag tctcttgggg acagcatctc ttcctcatct acattgtccc aaggaagcac
    10981 aatacacaac gtatcataca gcagattcaa aagcagaatc tgaattgaag tcataggcag
    11041 gaacggtaaa aaggcactgg cacaaatgat ggaaaaaata tttccaaagt tagagctagc
    11101 ggtgatttta atatatttca gcatattggt aaaagttttt cgcccctcca ttacaccttg
    11161 ctccaaaaca ttcaagtcct tttgcagcaa aaccacatcg gcagcatctt ttgctgcgtc
    11221 cactgccgta tctacagaga ttcccacatt tgcttcattc agtgccggaa tgtcgttgac
    11281 tccatcacca agaaatccca cggaatgacc attatcctgc atagcagaga caagacgcac
    11341 cttatgtccc ggagtaagct ctgcaaaaac atgagtatgt tccacagcct ttttaagttc
    11401 acagtctgtc atttcatcca gttgagtacc agttaagata cgctctgtat aaatacccac
    11461 ccggcggcaa acagacacag caatcgctgc ctggtcccct gtcagaatct tagggataac
    11521 ttttaatctt ttgagtgcag ttacagactc ctttgctgtc tgctttggtg catcaaagaa
    11581 ggatagatag ccaactagag tcatgcccca ttcgtcatca ggagttattt tcttttgcgc
    11641 tcccacattt tttcgtgcca ccgcaatgac cttcattccg tcctgtaaca tttcacctac
    11701 tacagaagat acactctgtc tcgcatcctg ccccatgggg agaagttttc cacgatattc
    11761 tacatggttg cagcgtgaga atatatgttc aatatcacct ttcataataa gctgactatt
    11821 cccattgcta tcctgtacaa gtgtactgac aaacttacga gcatagtcaa agggaatttc
    11881 atcagctttt tggaattttg tcagaagatt tgcgtaatgg gcttcccgcc ctggcatggt
    11941 attgcaggca agaatggcat tatcaatggt attgcagaca ccagaatgat agcagctatt
    12001 cagataagca agatcaagaa cctctgcatt ttcattccca aaaatatcca tataatattc
    12061 cagcaggatg ctttcattgg taagtgttcc tgttttatcc atacaaagca catccatgct
    12121 accaaagctc tgcatggcat taatatcctt gataatggtc tgctttttgc tcatagcaag
    12181 acttcctttg gcaaggcagg ctgtaataac cataggaagc atttccggca tcagacctac
    12241 agcaactgac agggcgaaag caaaagattc catccatttt ccatcagtaa tccccagtaa
    12301 tataaataca atgggaacta atatcgccat aaaacgtatc atcacccagg cgatggaatc
    12361 ggctcctttt ttaaaggaat ttttatcatc agaatccggt ttggtaaatc ctccatacag
    12421 ggtatctttg cctactgcca gtacaatgcc ttcccctttt ccactgatga ctgtggttgc
    12481 cataaaagcg aggttttcaa gctgagtcag tgtatcctgc tctccgtaac tgagttttcg
    12541 gcagctcttt tcaatgatgg cgctctcgcc agtaatcgca gcctgagaga taaagagatc
    12601 cgtaatcttc gtcaatctga tatccgccgg aacacgatca cctgcagaga atagtacaat
    12661 atcccctacc actaattctt cgccaggaat ctctattaac tttccatcac gcctcactgt
    12721 gacgctttca tgaactaggc gatcaagctg agcagcagcg ctctttgctc gcagctcctg
    12781 aatcagacga attacgccac taattacgat catggaaaag atgataatgg cggtagtagc
    12841 atttctcgca aaattggatg ctacgaaaac atccgtaaca agagaaacaa tgcccagaac
    12901 aaaaagaatc acatgaaacg ggttaataaa tgcccgtctc aaccgttgca tcgtcgtatc
    12961 atttttccgc ccattgaagc tgttcgctcc gtatttctcc cgcattgaac cgatttgctc
    13021 aatggataaa ccatccggag atgagccaat gtctcgataa atttctgatg ttctacagta
    13081 tgcgtatttt ttgatacgac tatcaaatag tgttgctttt gacacgaaac atcccctcct
    13141 ttataagtat aagtaataac attttaacac agtgttctga aaatgctata tttatattct
    13201 tgcttttttc ttgcaattta ctttgatatg gcatttttca gctcgatcaa atccgtctcg
    13261 ttagggcgag ataaatcctt atcaaagttt tcaaccattc cttctaaatt tggagcacgg
    13321 atggatacgg caagcatttt ctcatagcgc tctcgcacat aaataggcat ttccccttga
    13381 cacatatgag tgctgacaaa cttcttcttg gttttcacct tgaccatgta tcaaatttaa
    13441 atgaactact tagaaaagtt gctcataata atatttgtat tatgagtgat agaatgacaa
    13501 aagtggcagt atggaaaccg agtgtaaaaa caatacaatt agtttgtatg gaatatctga
    13561 actacataat tgaccactct gtaatttatg aaaaaataca atgcgcaaat tggaacggga
    13621 cagaagaaac caatagtatt tttaataatt ccccttcacc attgattact cttatctatt
    13681 cttgcgattt acaacaaaat aaaacaacat aaattttaaa tacgttgact ggcataattc
    13741 atatgtatag taagtctaca attaagatgc gctttttcta atccaaatat attaagaaaa
    13801 aagttttgcg aagccattaa tactttgttt aagatgtctt tcataaatat aaagaataat
    13861 gctcttaaca aaagcgtgca aattcctaaa gaaatgcacg ctttcaataa ttatcctata
    13921 atcttccaat tgctctcctt atgtagcact aattcaaact gcgatacctg tgttgccttt
    13981 gtctgattat caatgaattt cacggcaacc ttgactttca cattgtcccc atcaaccgta
    14041 aagatagggt ttaccaattc agaatagagg tagtccctgc cgatagactc aagcacattt
    14101 ccagacacat agtaagcaag ctccttttct gtggctgttg ggtatagctt aaagaaagtt
    14161 tccagaaatg cagtagcgtc atttatggta tccgcgtcta cacttgcgtc tgcttctggt
    14221 gtctttggtt catagtctga tttctcgatt gctggtgcaa gggtagggtt ctgaataatt
    14281 accatattcc cgccagcgtc cacatgaact tttacggtat aggttgcctt aaccgctgtt
    14341 gtctgttccc cctcttttat ctgctgatct acttcgtagg tagcggaaaa agtgtccgtt
    14401 ccagactgtt caatgctcca tacaatcaca tctgtaatgg cagagctggt cggtatatcc
    14461 gttctaatgg tatccatatt caagtcctgc aattcctttg tcagataacc gctgattgcc
    14521 tgcgtccttg cgtcaatcgc ttctttgctg ttactccatg tgtaatagga ctttgcaaaa
    14581 ttcttcacga aattttctat cccgttggtg tcctgcaagc gaagctcaat cacttctttt
    14641 tcatgggtcg tgtgctggtc aatagcggta aaattcttat atactccaaa gctcacgctt
    14701 gcaataagca ccacccacaa tgcaatcacg gttttcttat gtgtgcctac cttgacagta
    14761 cgtacctttt tttctttgac attttctgtc tgtttcttat tcttcttaaa catatttttc
    14821 aagtcctttc tattgtttta ctcgtcctgc accgattaag tgctgttgcc agtaactact
    14881 acttaggtct gtatatccta tcgggt
//
LOCUS       DAJMZY010000100        14905 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.101, whole genome shotgun sequence.
ACCESSION   DAJMZY010000100 DAJMZY010000000
VERSION     DAJMZY010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 14905)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14905)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14905
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.101"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            complement(<1..985)
                     /locus_tag="OE968_002969"
     CDS             complement(<1..985)
                     /locus_tag="OE968_002969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCP7220230.1"
                     /translation="MQIKIGKVIQCLRKERNLTQEQLAKFIGVSTPAVSKWESGNSYP
                     DIELLPLLADFFNVSIDKLLNYKIDLSEEEVMKIYKELESGFARIEIDLSTEEPKEEF
                     RQDLESVKKLSNMYIEKYPKSYLLKLRICSLYQMYSYKFGKSELNDRVKETMNILEDI
                     VRNTDDIQIKETALIILSNAYCMLEDYEKAELYLNMIHKSIGDTSVNLAMIYLKQNRL
                     EEAEILLQNKLFSNVFNISMDCKGIINVYKNQYKELKKKLENRNFNKNAIEREMEYIK
                     NKLLGYANLSLEIKKMLSEDKGAFFSMYMDYMELSLIFLFFNMKEEAKKALY"
     gene            complement(1450..2385)
                     /locus_tag="OE968_002970"
     CDS             complement(1450..2385)
                     /locus_tag="OE968_002970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HCP7220231.1"
                     /translation="MKCTNFTFKGEEGLDIYTYKWEDENIKKPKAVIQIAHGMAETAQ
                     RYETFAKVLTKNGYIVYINDHRGHGKTAKIIENVGHLAEKEGFRCLVEDMYTLTNIIK
                     KENEDLPIYLFGHSMGSFASQRYIMDYSNNLSGLILCGSNGKQGIILNLAHLIINREI
                     KKYGRRSKSNKINNLIFGGEIIRRNEKTKFDWLSRDKEQVEKYINDPFCGVVCSCGFF
                     YDLVQGLKEIEDKENLKKVPLDIPIYIISGDKDPIGKNGKGVLRLRDRYIKLGVKDVT
                     CKLYKDGRHELLNEINREEVFEDIICWLNNKIEIL"
     gene            2673..3239
                     /locus_tag="OE968_002971"
     CDS             2673..3239
                     /locus_tag="OE968_002971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HCP7220232.1"
                     /translation="MDYSNELKELFLMNQTYATLFTLTNKIQIEGDKYFGILTSRQYM
                     TILSILHLPEEETTLNNIARKMGTSKQNINRLVANLEKNGYVDVIPSPHDKRAINVKV
                     TDLGKKVMVTCSRTGINFMADVFHEFTKDELETLWSLLKKMYRFNGEEQDGFEEDANF
                     MEYEEIDKIKSEALEEFAKRRNRVNKKD"
     gene            complement(3430..5466)
                     /locus_tag="OE968_002972"
     CDS             complement(3430..5466)
                     /locus_tag="OE968_002972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin domain-containing protein"
                     /protein_id="HCP7220233.1"
                     /translation="MDSNRKPNNLINEKSPYLLQHAYNPINWYSWNDEAFKKAKEEDK
                     PIFLSVGYSTCHWCHVMEKESFEDEEVAEIMNRNFVAIKVDKEERPDVDSVYMTVCQA
                     MTGSGGWPMTIIMTPDKKPFFAGTYFPKYSRYNRPGVIDLLENVSEKWNTSRDILIKS
                     GDEIIEALKDDFGVKNTEGDLSKEMLSSSVRVFKAIYDEKYGGFGNAPKFPSPQNLMF
                     LMKYYSIEKDKDVLKMVEKTLDGMYRGGLFDHIGFGFSRYSTDKKWLAPHFEKMLYDN
                     AMLTIAFLDAYKITKKELYKEIAIKTIDYVVREMKDKEGGFYSAQDADSEGEEGKFYT
                     FNPLEIIEVLGEEDGIFFNNYFDITSSGNFEGKSIPNLIKNKEYERHNEKIADLSKKV
                     FEYRKERTSLHKDDKILTSWNALMIVALTKAYSTLKNDIYLEYSNKCLNFINNNLVNE
                     SGRLLARYRDGSSDYLAYLDDYAFLIWAYIELYESTFNMKYLEKALNLNESCINLFWD
                     YEKSGFYIYGKDSENLIARPKDLYDGAIPSGNSVQLYNLIRLAKITGDNRLEEMSYKQ
                     LKLYVDNVKSSPTGYSFYMLSLMFELYSTKEIICIFKEDSDLIAFKELISENFIPNAT
                     FLAKKYNEENTIIGFLNNYILKDDKTSYYVCQSNSCSQPINDLQKLKDMILGVE"
     gene            complement(5640..6317)
                     /locus_tag="OE968_002973"
     CDS             complement(5640..6317)
                     /locus_tag="OE968_002973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HCP7220234.1"
                     /translation="MFKHDKALLKEVKVERPNPQYAVLMQEQLGGANGELKAAMQYLS
                     QSFRIKDPQIKDLFLDIAAEELSHMEMVAQTINLLNGHDVDYNSVNTGEIETHVLTGL
                     SPVLINSSGAPWTANYVTVTGDLVADLLSNIASEQRAKVVYEYLYRQIDDKYVKETID
                     FLLNREEAHNALFRDALNKVKDTGSNRDFGVTEDSKLYFDLSTPGPNHDTKIDINPPS
                     FEKPLKK"
     gene            7034..7210
                     /locus_tag="OE968_002974"
     CDS             7034..7210
                     /locus_tag="OE968_002974"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220235.1"
                     /translation="MEQKESKIVYSKGGSGTYSAKISLPLSQLEKMGFTREKRKAVVI
                     FKEDEIIIKKSDEE"
     gene            7758..7943
                     /locus_tag="OE968_002975"
     CDS             7758..7943
                     /locus_tag="OE968_002975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB/MazE/SpoVT family DNA-binding
                     domain-containing protein"
                     /protein_id="HCP7220236.1"
                     /translation="MILLEQRKLRVAFNKSGKGSFTPRLILPMSWIKEMNISPDERDV
                     LVTFEDGKIIIEKTENE"
     gene            complement(7984..10383)
                     /locus_tag="OE968_002976"
     CDS             complement(7984..10383)
                     /locus_tag="OE968_002976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HCP7220237.1"
                     /translation="MIFKKYIKSLLIVVSVTLIMNKSILFVNALDLESNNNIKSYKRK
                     NVKEIDISNKFVDESFRRDIVEKVLDNRDDPLTNEVASKDNYKIYESDLNKIESCLEL
                     DLHKNPDVSNPNKIDNLDGIENFRNLEKLDCSSNNLESVDLSKNIKLKYLDISGNKIL
                     NINLKNNNLINELHCDANKLSSLDLKNNKNLVSLFFTSNELTEIDLSNNVNLENLQFL
                     NNNLKSIDLSHNKKLKSLNCTNNKLKSLNLSNNVFLKNLSCSGNNLSKLNIKGLTSLE
                     YLGCAKNKLQDLDVSTNIKLDSLFCGKNSLTKIDISKNKELKSLECSGQYIEKSIIKN
                     GENIVVDIGIENSKLKELYPQNYNISTGFLTWKNISEFPNNVSYSLEYEYGPVNDVET
                     MDVNISIDKLVKCRIRYIDYDGSIINEKEISDNSSINEIQINPQRENYEFNGWRNNKD
                     EKIYTSEQVSKLVFDDSTDFIATYKRKSTGSSGSSGGTSSKEDFNIAPSKEKLTGADR
                     NETSVKISQKGWNKADNIVLINDSSISDALSATPFAKSKDAPILLTKNNNLNKLTEKE
                     INRLEAKNVYIVGGLKSVDEKVVSDLKKKGLNVIRISGNDRYETSIKLAKELDKNSNL
                     SKVVVVNGEKGLADAVSMGAISAKEEMPILLTNQNDDMKDIKDLIANKNISKSYVIGG
                     ESLFNNKEVNNTLPSVTKIAGSDRTETNSKVISHFYSKDTLNDLYVAKNGMNKQDDLV
                     DALSVGVLAGKTESPVVLVGNGLDDSQKELIKNKKFKNITQIGGNGNEKAFNEVENLV
                     K"
     gene            complement(10477..11289)
                     /locus_tag="OE968_002977"
     CDS             complement(10477..11289)
                     /locus_tag="OE968_002977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HCP7220238.1"
                     /translation="MKICITVGHSILKSGACTSADGVVNEYQYNKSLAPVLADTFRKE
                     GHKADVIICPEKQFKTKAEEKTYKIPRVNSGGYDLLIELHLNASDGQGKGSEVLYYSN
                     KGLEYATRICNKLGTVFRNRRAKLDKGLYILNSSNPTAVLIESFFCDNKEDYEKAKKL
                     GHEGIAKLIVEGVLNKNINNEGVKQMYKHTIVYDGEVDKISATVVGWGYNDGKILICD
                     IKDYVPGQTQNLYVIGGAACEKIGSMTKEKFTMIKGNDRFDTLYKALDFINR"
     gene            complement(11368..12231)
                     /locus_tag="OE968_002978"
                     /pseudo
     CDS             complement(11368..12231)
                     /locus_tag="OE968_002978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429958.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Abi family protein"
     gene            complement(12492..12749)
                     /locus_tag="OE968_002979"
     CDS             complement(12492..12749)
                     /locus_tag="OE968_002979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HCP7220239.1"
                     /translation="MDNLISFIPEQLLILVAALYVIGAGCKKYKQLDNKYIPVVLLIL
                     GIGFSIWMLGLNPVAVLQGVICWGVAIGVNQTYKQFKDGEK"
     gene            complement(12753..13043)
                     /locus_tag="OE968_002980"
     CDS             complement(12753..13043)
                     /locus_tag="OE968_002980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220240.1"
                     /translation="MEEISINLLCAVAGVVISYLAFRNSSNRKIQDDTETTTKLEQQI
                     TFLCENVRDIKHDVAKFNTSFLDISERVAKVEASTKQAHLRIDEIINRIGGK"
     gene            complement(13074..13640)
                     /locus_tag="OE968_002981"
     CDS             complement(13074..13640)
                     /locus_tag="OE968_002981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220241.1"
                     /translation="MTFKELVNKVRNLVLEAKNVTIEDTESKFTSENVEGALKECIDR
                     ADEAFQEADSGKTLLSTAIGSPATSEQTFQDYANYITGFKSNISNLETQLKSKYSIRY
                     GPIDGYDGNPFSANFGKSASYLIVYVYFRRSVYYYNPSGSSLGSNTGGSERAWITIDS
                     NKTGFSVHSYDTSYEPYPFTGYYIACFA"
     gene            complement(13671..13841)
                     /locus_tag="OE968_002982"
     CDS             complement(13671..13841)
                     /locus_tag="OE968_002982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220242.1"
                     /translation="MYNLLKLMIEQKNYSTKEDLQHKIDVFYAVNRITEEQYLELTSL
                     LNKEETPAEPIK"
     gene            complement(13853..14200)
                     /locus_tag="OE968_002983"
     CDS             complement(13853..14200)
                     /locus_tag="OE968_002983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220243.1"
                     /translation="MNRNNRIIYDQTGNIWLQTGEATGDIQEWSKITELNFLDVEFGS
                     IDYSKQYIESINPVTKEPIIKDIEVILTDEQKRLQALEKELSMLKEENKNRDSEIVNT
                     AFEVENIKLNNNL"
     gene            complement(14221..>14905)
                     /locus_tag="OE968_002984"
     CDS             complement(14221..>14905)
                     /locus_tag="OE968_002984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220244.1"
                     /translation="KVLSISKNIMPLPENVNLNDISTKLVEVNAGFKVGKTSIINTLA
                     LKNIEASLNNTLVELSEKIKTSFDSSDTSVQDLQNQVTQKNNTITQLETELSKRKRFI
                     TGTYTFTKTDAENFNLSIYDKEGTSKTLTIPVNMGFSPSLIVLSGVTFSTTSKSYVYF
                     DNVCNSNFYNFGYNSDSTHSNPKAVGILNVSNVGYSSLVLTLYKLSMSEAVGIWAKEG
                     ATLTYKIYI"
BASE COUNT         4900 a         2401 c         1566 g         6038 t
ORIGIN      
        1 tatataaggc tttttttgct tcttctttca tgttaaaaaa taaaaaaatt agagataatt
       61 ccatataatc catatacata ctaaaaaatg cacctttatc ttcactgagc atttttttta
      121 tttctaaaga aagatttgca taccccagca acttattttt tatatactcc atttctctct
      181 caattgcatt tttattaaaa tttctattct ccaatttttt ctttaattcc ttgtattgat
      241 ttttgtatac attaattatt cccttacaat ccatgcttat attaaataca ttactaaaca
      301 atttattttg aagcaatatt tctgcttctt caagtctatt ttgctttaaa tatatcatag
      361 ctaaattaac acttgtatcc cctattgact tatgtatcat atttaaatac aactctgcct
      421 tttcataatc ctccaacata caatatgcgt ttgataatat aataagagct gtttctttta
      481 tttggatatc atctgtattt ctcactatat cttcaagaat attcattgtt tcttttactc
      541 tgtcattaag ttcactctta ccaaatttat atgaatacat ctgatacagc gaacatatcc
      601 ttagcttcaa taaatagctt ttaggatact tctctatata catattggaa agctttttta
      661 cagattctaa gtcttgtcta aattcttctt ttggttcttc tgttgataaa tcaatttcaa
      721 ttctagcaaa gcctgattct aattctttat aaattttcat tacttcttct tcacttaaat
      781 caatcttgta atttaaaagc ttatcaatag acacattaaa aaagtctgct aataaaggca
      841 ataattctat atctgggtaa gaatttccac tctcccactt agatactgct ggtgttgaca
      901 cacctataaa ctttgctaat tgttcttgag ttaaatttcg ttcttttcta agacactgta
      961 tgactttacc tattttaatt tgcatatata cctccctagt acatctgttg taatttaagt
     1021 atataaaaaa aatatttact agtaaatcga gggaaagtta acaaaatgtc tgtaatttaa
     1081 ccattggtta tattttaatc taaaacccta tctcattggc ttgaaatata aaatctatta
     1141 attaagttta agtataacct aattaataga ttcacattaa atagcattta aatatttaga
     1201 ttttctcttt attacaactt actatattta aactttcaag gaattttaaa taaaataaat
     1261 tccatataca atgataatca tactgagtgt taataattta tttataataa cacccaccta
     1321 ttcaataaat ggcattatag caaaaaatca cttctaggct ctctcttttc tactttgcat
     1381 atacataatc cacttttcaa atattatata taaataaatt taaagcaaat atatcattat
     1441 atttttttat tacaatattt ctattttatt atttaaccaa caaattatat cctcaaaaac
     1501 ttcttctcta tttatttcat tcaacaattc atgccttcca tctttgtaaa gtttgcaagt
     1561 tacatctttt actcctaatt ttatatatct atcccttagt cttaagactc ctttaccatt
     1621 ttttcctatg gggtctttat ctccagatat tatgtaaata ggtatatcaa gtggcacttt
     1681 ttttaagttt tctttatcct caatttcttt taacccttga actaaatcat aaaaaaagcc
     1741 acaactacac actactccac aaaatgggtc atttatatat ttttcaactt gttctttatc
     1801 tctacttaac cagtcaaact tagtcttttc atttcttctt attatttcgc caccaaatat
     1861 caaattattt attttattac ttttagaacg tcttccatac tttttaatct cacgattgat
     1921 tatcagatga gcaagattta gaatgattcc ttgctttcca tttgaaccac atagtataag
     1981 accagataaa ttattactgt aatccattat atatctttga cttgcaaatg aacccatgct
     2041 gtgtccaaat agataaattg gcaaatcttc attttctttc tttataatat ttgttaaagt
     2101 atacatgtcc tctacaagac atctaaatcc ttctttttca gctaaatgtc caacattttc
     2161 tattatcttt gcagtttttc catgacctct atggtcattg atatatacta tataaccatt
     2221 tttagtaagt accttggcaa aagtctcata cctttgtgca gtttcagcca ttccatgtgc
     2281 aatttggata actgcctttg gtttttttat attttcatct tcccatttat atgtatatat
     2341 atctaaacct tcctctcctt tgaaagtaaa gtttgtacac ttcataatta tccctccaga
     2401 ttgattttat tcagtatatt aatttatata ttatattaca agtattttca agtcaaaatc
     2461 tttctaaaaa atttaagaat tattaattcc tcatagaaat tatcattggt acatagaagt
     2521 ttttacataa aattatacaa taatttaatt aattaatagt tacataaaaa agtaatactt
     2581 taatatattt tgacaccata ttgacattag aattaattca tgatattctg ttttcgacaa
     2641 aacaacatct aaaaataaag gagatatatt tcatggatta ttcaaatgaa ctaaaagagc
     2701 tctttttaat gaatcaaaca tatgcaactc tttttaccct tacaaacaaa atacaaatag
     2761 aaggagataa atattttggt atacttactt caagacagta tatgactatt ttatcaattc
     2821 ttcatttacc agaggaagaa acaacattaa ataatattgc aagaaaaatg ggtacaagta
     2881 aacaaaatat aaatagacta gttgctaatc ttgaaaaaaa tggatatgtt gatgtaattc
     2941 caagtcctca tgataagaga gcaattaatg ttaaagttac agacttagga aaaaaggtta
     3001 tggtaacatg tagtaggact ggaataaact ttatggcaga tgtatttcac gaatttacca
     3061 aagatgaatt agagacctta tggagtttac taaaaaaaat gtatcgtttt aatggtgaag
     3121 aacaagatgg ctttgaagaa gatgctaatt ttatggaata tgaagaaata gataaaatta
     3181 aatctgaagc acttgaagaa tttgcaaaaa gaagaaatag ggtaaataaa aaagattaat
     3241 actatcgcat ctataatacc acttttttat agtacaatat tttatataac tataatgtca
     3301 tttttatttt ttaacaaaac aatcattaca tagattaggt gttcttagga actctttttc
     3361 tgttttttat acaaaaaaag gagatgatta gacttttatt ttaaagcatc tcctttttcg
     3421 ctattatgat tattctactc ctaaaatcat atcttttaat ttttgtaaat cattaattgg
     3481 ttgactacaa ctattacttt gacacacgta ataactagtc ttatcatcct tcaatatata
     3541 gttatttaaa aaacctataa tagtgttttc ttcattgtat ttctttgcta aaaaagttgc
     3601 atttggtata aaattttcac ttatcaattc tttaaatgca attaaatcag aatcttcctt
     3661 aaaaatacat ataatttcct tagtagaata aagttcaaac atcaatgaaa gcatataaaa
     3721 gctgtagcca gttggagaac tctttacatt atccacatac agttttaatt gtttatatga
     3781 catttcttca agtctattat ctccagtaat tttcgcaagt cttataagat tgtataattg
     3841 aacagaattt cctgatggaa tagctccatc atacaaatct tttggtcttg ctattaaatt
     3901 ttcactatct ttaccatata tataaaatcc acttttttca taatcccaaa aaaggttgat
     3961 acagctttca ttcaaattta aagccttttc taaatatttc atattaaatg ttgactcata
     4021 aagctctata tacgcccaga ttaaaaaagc ataatcatct aaatatgcta aatagtcgga
     4081 acttccatct ctatatctag ctaataatct acctgactca tttacaagat tattatttat
     4141 aaagttaaga cacttatttg aatactctaa atatatgtca ttttttaaag tactatatgc
     4201 ctttgttaaa gcaactatca tcaatgcatt ccatgatgta agtatcttgt catctttatg
     4261 caaagatgtt ctttcttttc tatattcaaa taccttttta ctaaggtcag ctatcttttc
     4321 attatgtctc tcatattctt tattttttat aagattagga atacttttgc cttcaaaatt
     4381 tccactacta gttatatcaa aataattatt aaagaaaatt ccatcttctt cacccaaaac
     4441 ttcaattatc tcaagaggat taaatgtata aaatttacct tcttcacctt cactatcagc
     4501 atcctgtgct gaataaaacc caccttcttt atccttcatc tctctaacta cataatctat
     4561 agtttttata gcaatttctt tatataactc tttctttgtt attttatacg catctaaaaa
     4621 agctatagta agcatagcat tatcatatag cattttttca aaatgaggag ccaaccactt
     4681 tttatcagta gagtatcttg aaaacccaaa tccaatatga tcaaacaagc ctcctctata
     4741 cattccatct aaagtttttt ccaccatttt taacacatct ttgtcttttt ctatactata
     4801 atatttcatt aaaaacataa gattctgagg acttggaaat ttaggagcat taccaaaacc
     4861 accatacttt tcatcataaa tagccttaaa tactctaact gatgaactca acatctcttt
     4921 tgataaatca ccctcagtat tttttacacc aaaatcatcc ttaagagctt ctattatttc
     4981 atctccagat tttattaata tatccctgct tgtattccac ttttcagata cattctctaa
     5041 taaatctata actccaggtc tattatacct tgaatatttt gggaaatatg ttcccgcaaa
     5101 aaaaggtttt ttatctggtg tcattattat ggtcattggc catccaccac tacctgtcat
     5161 ggcttggcaa actgtcatat acacgctatc tacatcaggt ctttcctctt tatctacttt
     5221 tatcgccaca aagtttctat tcattatttc agcaacttct tcatcttcaa aagattcttt
     5281 ttccataaca tggcaccaat gacatgttga atatcctaca cttaaaaata ttggcttatc
     5341 ctcttctttt gcttttttaa aagcctcatc attccaacta taccagttta taggattata
     5401 tgcatgctgt aaaagatatg gagatttttc atttattaga ttattaggtt ttctattact
     5461 gtccaaaata ccacctcatt tgttatttta ttatatgttt tgcaataaac aaatagatat
     5521 acacttataa taagtgtata cccattttta accatacata tttaattttt catataatta
     5581 attctcctag taaataattt ttataactac taaaacaaaa caacataaaa aatatcaaat
     5641 tattttttta aaggtttttc aaaagaagga ggattaatat ctatcttagt atcgtgattt
     5701 ggccctggag tagacaaatc gaaatataat ttagaatctt ctgtaactcc aaaatctcta
     5761 tttgaacctg tatctttaac tttatttaaa gcatctctaa atagagcatt atgtgcttct
     5821 tctctattaa gtaagaaatc tattgtttct tttacatatt tatcatctat ttgtctatac
     5881 aagtactcat aaactacctt agctctttgt tcagaagcta tatttgaaag taagtcagct
     5941 actaaatccc ctgtaactgt aacgtaatta gcagtccaag gagctcctga tgagtttatt
     6001 aagactggtg atagaccagt taatacatgt gtttctattt cgcctgtatt aactgaatta
     6061 taatcaacat catgtccatt taataaattt atagtttgtg ctaccatttc catatggcta
     6121 agctcttctg ctgctatatc aagaaataaa tcttttattt gagggtcttt tattctaaaa
     6181 ctttgggaca agtattgcat agctgctttt aactctccat ttgcaccacc caactgttct
     6241 tgcattaaaa cagcatattg aggatttggt ctttctactt ttacttcttt taataatgct
     6301 ttatcgtgtt taaacatatg aatacctccg taaattatta ttcaaaatta ttatttactt
     6361 aagttgtaat attattctag gttatttgtt tattgttgtt attttttaca agtgttggta
     6421 tttcaatgtt ttattaaggt cagttttgtt gtttatgttt tattatgttt aatttaaatt
     6481 tattctatta tttattttcg gtggcaaaag ggtggcaagt ttggttttgc cacccttatt
     6541 tttatttgta aaaaaatata gtttgtcaat ataactttat tgaaaaatat ggaaataaat
     6601 atcgcttttg ccggttcggc atattataat ataaatatag aaagggggtg aaaaggaaaa
     6661 tgagtagaat agaaagaaga aaaaaagata gagaaagcaa actcgccaaa gttaaaactg
     6721 ctctctctat cttacccatt ttaataaatt taattgataa actaattaaa ttattaaaag
     6781 atttatagtt ttgtaagcta ggaagaattt aatcttcttc ctagtgactt ctttctaaat
     6841 attataacac attttctata aaatatgagt gataaagttt ataaattctg tcttattata
     6901 gttgctataa ctatagtaat agacataata cttttatttt tacattttaa tatcaacaat
     6961 ataataggat taatagtaag cattttattg ttaatatttg ttacattaca atataaaaaa
     7021 ggaggaaaat agtttggagc aaaaagaatc taaaatagtt tacagtaaag gtggttcagg
     7081 tacttattcg gctaaaattt ctttaccttt aagccaactt gaaaaaatgg gatttacaag
     7141 ggaaaaacgt aaggctgtag ttatttttaa ggaagatgag attataataa aaaaatctga
     7201 tgaggaataa ctctaaaata agtgggtgta taatgtaaac atccacttat ttttattata
     7261 ttttgtattt tatattaata tattttatag ctttattgaa aaatatggaa tatttattga
     7321 ctttcacgtc acgtgatgat ataatataaa tatagaaagg aggtaagaaa ataaaaaact
     7381 tagaagggag gacaaagaaa gtggggagat tagaaagaag aaaaaataaa agagaaaaca
     7441 aatttaataa aattaaaaat gctttctctt tcacattagt tttaattaat ctagtactcg
     7501 caatactaag attgattaaa gaattataag tttcaatcct aggaggaaaa taccttcctt
     7561 ctaggtagct tctttctaat attataacac attttctaat ttaatatgaa taataaattt
     7621 tatagaattt gtatgattat tcttggtatc actatagttt taaatattat taatataata
     7681 ataagtttta cttttaaagc tcttattgct ttggtattta ctttattatt gctggcattt
     7741 attaatagta gaaaggaatg atattattgg aacaaagaaa acttagagtt gcattcaata
     7801 aaagtggcaa aggctctttt acacccagat tgatacttcc aatgtcatgg attaaagaga
     7861 tgaatatctc tcctgatgaa agggatgttc ttgttacttt tgaggatgga aaaataatta
     7921 ttgaaaaaac tgaaaatgaa taaaaaagga ggtagtaact atttccagtt actacctttc
     7981 aatctattta actaagtttt ctacttcatt aaatgctttt tcatttccat ttccaccaat
     8041 ttgagttata tttttaaact ttttattctt gattaactct ttttggctat catctaatcc
     8101 atttccaact aatactactg gagattcagt tttacctgca agcactccta ctgataaggc
     8161 atctactaaa tcgtcttgtt tattcattcc attcttagct acatataagt cattaagtgt
     8221 atctttgcta tagaaatgac ttattacttt tgagttagtt tctgttctat cagaacctgc
     8281 tattttagtt acagatggta atgtgttatt cacttcttta ttattaaata aagattctcc
     8341 acctattaca tatgattttg atatgttttt attagctatt aagtctttta tatctttcat
     8401 atcatcattt tgattagtaa gaagaattgg catttcctct tttgctgata tagctcccat
     8461 acttactgca tcagctagtc ccttttctcc atttaccact actacttttg acaggttaga
     8521 atttttgtct aattcttttg caagttttat tgatgtttca tatctatcat ttccagatat
     8581 tctaattaca tttaatcctt ttttctttaa atcagacact actttttcat caacagactt
     8641 taatccaccc actatgtaca cattttttgc ttctaatcta tttatttctt tttctgttaa
     8701 tttatttaag ttattatttt tagtaagtaa tattggtgca tctttagact tagcaaatgg
     8761 tgttgctgat aaagcatccg atatgctaga gtcatttatt aacactatat tatcagcttt
     8821 attccatcct ttttgactta ttttcactga tgtttcattt ctgtctgcac ctgttaattt
     8881 ttccttagat ggtgctatat taaaatcttc tttacttgaa gttccaccag aagaaccact
     8941 tgatcctgtt gattttcttt tataagttgc tataaaatca gtactatcat caaaaactaa
     9001 tttacttacc tgctctgatg tatatatttt ttcatcttta ttgtttctcc aaccattaaa
     9061 ctcatagttt tctctttgag gattaatttg aatttcattt atactagaat tatctgatat
     9121 ttctttttca ttgattatac ttccatcata atctatatat ctgattctac atttaactaa
     9181 tttatctatt gatatattta catccatagt ctctacatca tttactggac catattcata
     9241 ttccaaacta taacttacgt tatttggaaa ttcagaaata tttttccatg ttagaaaacc
     9301 tgttgagata ttataatttt gtggatataa ttcctttaat ttcgaatttt caattcctat
     9361 atctacaact atattttcac cattttttat aatacttttt tctatatatt gaccactaca
     9421 ttccaatgat tttaattctt tatttttact tatatctatt tttgttaaac tatttttccc
     9481 acaaaataaa gaatctaatt ttatatttgt agatacatct aaatcttgta atttattctt
     9541 agcacatccc aaatactcaa gacttgtaag tccttttata tttaatttac ttaggttatt
     9601 acctgaacaa cttaaatttt tcaaaaaaac attattactt aaattaagag atttaagttt
     9661 attgttagta caatttagag atttcaactt tttattatga cttaaatcta tactttttaa
     9721 attattatta agaaattgca aattttctaa gttcacatta ttacttaaat ctatctctgt
     9781 taattcatta ctagtaaaaa ataaacttac caaattttta ttatttttaa ggtctaaact
     9841 tgataattta tttgcatcac aatgtaattc attaataaga ttattgtttt ttaaattaat
     9901 gtttaatatt ttatttccac taatatctag atattttaat tttatatttt tacttaaatc
     9961 tacactttct agattatttg aactacaatc aagcttttct agatttctaa aattttctat
    10021 cccatctaaa ttatctattt tgtttgggtt ggaaacatct ggatttttat gtaaatctaa
    10081 ctctaagcaa ctctcaattt tatttaaatc actttcatat attttatagt tatcttttga
    10141 tgcaacttca tttgttaatg gatcatccct attatctaat accttttcaa caatatctct
    10201 tctaaaggat tcatcaacaa atttattgct tatatcaatt tcctttacat tctttctttt
    10261 ataagatttt atgttattgt tactctctaa atctaatgca tttacaaata atattgattt
    10321 gttcattatc aatgtaacac taacaactat cagtaatgat tttatatact tcttaaatat
    10381 cataatctac ccccatacct attaataata aataatattt atctaaatat taccatactt
    10441 atgattttca agaaatacta aaatatttta tataatctat ctattaataa aatctaatgc
    10501 cttataaagt gtatcaaatc tatcattacc ctttatcata gtaaattttt ctttagtcat
    10561 agaaccaatc ttctcacatg ctgcaccacc aatgacataa agattttgcg tctgacctgg
    10621 cacgtaatct tttatatcac atatcagtat tttcccatca ttataacccc aaccaactac
    10681 agttgcagag attttgtcaa cttctccatc ataaacaatt gtatgtttgt acatctgttt
    10741 aactccctca ttatttatat ttttatttaa tacaccttct acaattaact tagcaatacc
    10801 ttcatgacct agtttcttag ctttctcata atcttcttta ttatcacaga agaaactttc
    10861 aattaatact gctgtaggat ttgaactatt taagatatat aatcctttat ctaatttagc
    10921 tcttctattt ctaaatactg tacctagctt attacatatt ctagttgcat attctaaacc
    10981 tttattacta taatatagaa cttctgaacc ttttccttga ccatcacttg catttagatg
    11041 tagttctata agtaaatcat atcctccact attaactcta ggtattttat aagtcttttc
    11101 ttctgcttta gttttaaact gcttttcagg gcatattatt acatctgcct tatgaccttc
    11161 ttttctaaat gtatctgcta atactggtgc aagagattta ttgtattggt attcgttaac
    11221 tactccatca gcagaagtgc atgcaccact ttttaaaata ctgtgtccta ctgtaataca
    11281 tattttcatt atttattttc ctccttcttt tcaataaaaa aacacttaca tatagtaagt
    11341 gtttataaac ttcttaaagt aactatttta tttagccaat atctctatcc aattattagg
    11401 aaaaccaata agctttaagt ctatagaatt attataatca ttaattaact tttgaagttt
    11461 tataaaaaaa ctattccaaa ttaatttatc catagtcaaa tgcttcatag caagtatata
    11521 agaaaatatc tttttattat ccaagttata ctttttatat tcgtttttta ttgttataat
    11581 acggaaatta ttattatata ttctaccata atgagcgcat tgatttctga cctgtgttaa
    11641 tgattgtaac caagatttaa ctaataaagt attcactcta cacaaattat tttttatgta
    11701 tctagtatct tctggcaaca tgtttgaata taatttttac aacataccaa aagtcattat
    11761 ttccgttgca acccaaatgg gaagttttcc tttatatttt tctttatggt gtataataaa
    11821 aagcttatct gaattattat ttttttctct ctctaatgct gtcaaaaaat taatatagaa
    11881 tttttcatct ttgaaactct ccctttatag atatccacaa gcaccatgtt taattgctaa
    11941 tgtatatgca atgtatgtcc taaatgctat ttctatgctc cctaacaaat ctgttaataa
    12001 tatcctaaat tccttattaa acctatatat atcataaact tcttcaaacg tagttccttc
    12061 tttatatgag ccatcatcat tcttaaaact tagaagatat gctgtaaacc tataataatt
    12121 gacattactt aatacaaatt tagcatcttc tttatcattt attattaatc ctctactttt
    12181 taaaatatct atttgttcat caaatgtttt ttcttctttt acttcaacca ttgttttcac
    12241 cttttcatag atatactttt atataataaa acccaccaat taatattagt gggtaaattt
    12301 atctgtcccg actatttgag ctataaaaga agcttggcgg gttccttcaa aaatcaatgt
    12361 cccgtatatt tgagcatata aatgctttac gagttctgta ctattattat atacttatta
    12421 gctataaaag tatactctat ttaatgaaat tttttaaatt tttgtgagta ataatatttt
    12481 tgttaatttc attacttttc accatcctta aactgtttgt aagtttgatt tacacctatt
    12541 gcaactcccc aacaaattac accttgtaag actgcaacag gatttaatcc tagcatccat
    12601 attgagaaac ctattccaag tatcaataac actactggaa tgtatttatt atctaattgt
    12661 ttatattttt tgcaacctgc tcctataaca taaagagcag ctactaaaat tagtaactgc
    12721 tctggtataa aacttattaa attatccatc ttttattttc ctccaattct atttataatt
    12781 tcatcaattc taagatgtgc ttgttttgta cttgcttcta cttttgcaac tcgttcactg
    12841 atatctaaga aacttgtatt aaactttgct acatcatgct ttatatctct tacattctca
    12901 cacagaaaag ttatttgttg ttctaatttt gtagttgttt ctgtatcatc ttgtatcttt
    12961 ctgtttgagc tatttctaaa tgctaagtag gatattacaa ctcctgcaac tgcacataat
    13021 agatttatgc taatttcttc catacatcct cctagtttta ataatataat ttattatgcg
    13081 aaacaagcaa tataataacc tgtaaaagga tatggctcat aactagtatc atatgaatga
    13141 actgaaaaac cagttttatt gctgtctata gtaatccatg cacgttcaga acctcctgta
    13201 ttacttccta aagaactacc actgggatta taataatata cacttcttct aaagtaaaca
    13261 tagacaataa ggtaacttgc actcttgcca aaattagcag aaaaaggatt accatcatat
    13321 ccatcaatag gaccatatct aatagaatat ttgcttttca attgagtttc taaattgctt
    13381 atattgctct taaatcctgt aatatagttc gcataatctt gaaatgtttg ttctgatgta
    13441 gcaggagagc cgatagcagt tgataaaagt gtttttccac tatcggcttc ttgaaaagcc
    13501 tcatctgctc tatctataca ttctttcaat gctccttcta cattttcact tgtaaattta
    13561 ctttctgtat cttctatagt tacattcttt gcttctaata caagatttct aactttatta
    13621 actaactctt taaaagtcat ttagtcacct tctttcaata aaaaaagaac ctattttatt
    13681 ggttctgctg gtgtttcttc tttatttaat aaacttgtaa gttctaaata ttgttcttct
    13741 gtaattctat ttactgcata gaatacatca attttgtgtt gcaaatcctc tttagtgcta
    13801 tagttctttt gttctatcat aagttttaat aagttataca tgttaattcc tcctataaat
    13861 tgttatttaa ttttatattt tctacctcaa aggctgtgtt tactatctca ctatctctat
    13921 ttttattttc ttcttttaac atgcttaatt ctttttctaa tgcttgtaat ctcttttgtt
    13981 catctgttaa aatgacttct atgtctttga tgattggttc ttttgtaact ggatttatag
    14041 actctatata ttgtttacta tagtctatac taccaaattc aacatccaaa aaatttaatt
    14101 cagttatttt tgaccactct tgtatatctc ctgttgcttc accagtttga agccatatat
    14161 tgcctgtttg gtcgtaaatt attctattat ttctgttcat attatcacct cattttttta
    14221 ttaaatatat attttgtaag ttaatgtagc tccctctttt gcccatattc caactgcttc
    14281 tgacattgat aatttatata atgtaagcac taatgaagaa tacccaacat tagatacatt
    14341 aagaatacca acagctttcg ggttactatg agtagaatca gaattatagc caaaattata
    14401 aaaatttgaa ttacaaacat tatcaaaata aacataagat ttacttgttg tactaaaagt
    14461 tactccacta agtacaatta aactaggaga gaagcccatg ttaactggta tagtaagagt
    14521 ttttgaagtt ccttctttgt catatatact taagttaaaa ttctctgcat ccgtttttgt
    14581 gaatgtataa gttcctgtta taaatctttt tcttttactt aactctgttt ctaattgagt
    14641 tatagtattg tttttttgtg ttacttgatt ttgtaaatct tgcacactag tgtctgaact
    14701 atcaaaactt gtttttattt tctctgataa ctccacaagt gtattattta aacttgcttc
    14761 tatattttta agtgctaaag tgtttataat acttgttttc ccaactttaa atcctgcatt
    14821 aacctcaact aattttgttg atatatcatt taaatttaca ttttcgggca gtggcattat
    14881 attcttactt atacttaaca ctttt
//
LOCUS       DAJMZY010000101        14861 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.102, whole genome shotgun sequence.
ACCESSION   DAJMZY010000101 DAJMZY010000000
VERSION     DAJMZY010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 14861)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14861)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14861
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.102"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            568..1479
                     /locus_tag="OE968_002985"
     CDS             568..1479
                     /locus_tag="OE968_002985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YafY family transcriptional regulator"
                     /protein_id="HCP7220245.1"
                     /translation="MKINRLTEIIVILLNKKLVTAKELADRFEVSTRTIYRDIETLSM
                     SGVPVYMTKGKGGGISLIEEYSIDKAILSKKDKESLIVALKTLQATKYPEINSVVNKI
                     GSIFGEQNFSNWIEIDFTEWGSNFNEDDKFTKIKEAILRRNTINFNYVNSLSSQTNRT
                     VEPLKLMYKSKTWYLYGFCKLKDDFRIFRISRIRNLSIKDEVFSRKIIEEVCLNDSKV
                     IKENTITLKLRFKEKMLFRVFDDFNKDLITKNEDDTYDVITEFPIGEWIYGYILSFGD
                     NVEVLEPKDVRDNVITRLRELSKIYSL"
     gene            1654..2151
                     /locus_tag="OE968_002986"
     CDS             1654..2151
                     /locus_tag="OE968_002986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HCP7220246.1"
                     /translation="MNYEIVEINEKIVIGISKETTNKDGQAVNDIGELWKKFMGKGIY
                     NAIKGKKNDKTIGLYTDYQGDFTSPYSFVACCEVNSNSDKEKNLEELNTNNTVGESII
                     SKVIPAGKYAKFVIVGGQKEVGDFWFEFWQMDFDRTYISDFEEYQCNTFDTKKQEVHI
                     YIGIK"
     gene            2895..3257
                     /locus_tag="OE968_002987"
     CDS             2895..3257
                     /locus_tag="OE968_002987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HCP7220247.1"
                     /translation="MENKILIVDDAIFMRMIIKEALSKSGYNNLIEANDGEEACNIFK
                     YEKPDLMLLDITMPKKDGLEVLREIKKLDSSAKVVMCSAIGQENMIVEAIKLGALDFI
                     VKPFKTETLVKVVDNALK"
     gene            3322..3939
                     /locus_tag="OE968_002988"
     CDS             3322..3939
                     /locus_tag="OE968_002988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheC"
                     /protein_id="HCP7220248.1"
                     /translation="MINYLELDDVHIDALREIGNIGSGNAITALASMINSNVEVLIPM
                     VKILEYNEATNLLGGPENKVVCILLDMKGDINGMFMFLLDESITQLMLSSLFNKEEAF
                     LDEIEAIEISAIKEIGNIMASSYVNAIASMLNMTISVSIPDICIDMVGAVLNVPMIRF
                     SDVGDKVLFIENKFKMSDNYFTSHILMIPEMSSLREILVRLGLEV"
     gene            3936..4421
                     /locus_tag="OE968_002989"
     CDS             3936..4421
                     /locus_tag="OE968_002989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheD"
                     /protein_id="HCP7220249.1"
                     /translation="MNREIVVNIADMKIAYRPNVLVTYALGSCVGVCLIDKVAGIGGM
                     LHVMLPYSKDAINIENKCKFADTGINELIKSMENIGANRIYIKAKIAGGAQMFLGSSN
                     SVIASIGHRNVEAVKKTLLGLNIPILAEDTGMNYGRTIRFYTETGELLVDSINKGKKK
                     L"
     gene            4464..4982
                     /locus_tag="OE968_002990"
     CDS             4464..4982
                     /locus_tag="OE968_002990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-binding chemotaxis protein CheW"
                     /protein_id="HCP7220250.1"
                     /translation="MRFPDDPYLDYGLIDEGIKYLKFRVDEQDFGVELEKVIEITGNQ
                     EIIFIPELPTYSKGIINLRGKIIPIIDMRLRLKKDELMTTNCMYIVVTEIKDLVVGFV
                     VDRVDDIVSLEKSKISPPPRVTIEYSDYFVSGVGELEGKIITLLDLEKLLTDKDEVLI
                     DELINGFDCTIM"
     gene            5118..6077
                     /locus_tag="OE968_002991"
     CDS             5118..6077
                     /locus_tag="OE968_002991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HCP7220251.1"
                     /translation="MKNKQQGTILVVDDSVLMCDLIDKTLTKDNFKVKKAFNAIEAKE
                     FIEEFIPDIILLDIILPDNSGFEFCKEVKSNARTADIPIIFITSKNTDTDIVKGFGVG
                     AIDYMVKPFSMTELKARVIAHLEVKKSQDKLKKINNELESSLEKLNRLVVRDYLTGLY
                     NRRHIINQLMEQRRINKYSETSISLILGDIDDFKVINDTYGHEAGDFVLTVISSIIKK
                     NCRQIDTVSRWGGEEFLIMLTNTPIEGAKILSERIRKEIKEFDFNYKEHKIKCTITLG
                     VVEVNSNISLEENISLADKAMYEGKNLGKDCSVVSTMKGLKKI"
     gene            6103..7806
                     /locus_tag="OE968_002992"
     CDS             6103..7806
                     /locus_tag="OE968_002992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing protein"
                     /protein_id="HCP7220252.1"
                     /translation="MKREVKLSKLAIVLLIIIVLAVLAGIFSSISSYKAFEKVEKSIN
                     DMNNLRTQSQYIKDTTREISDVLRRYVFTGEKKNKDIYEKELYGKTRESALNKLEKIG
                     LTKSESNKILEAKEISDSLVPTEQSAIKAVESNDKSKAQSIIFGSDYINSQEKMDSLI
                     NEFQEDIVTRSNSKIVEVKKELQSLILRTIFILSLLIILTIIEYTVIKLKIVIPINKV
                     EKHFSRIASGDLRTSIDVEESKSEIGLLVSSVKKMQSMLLNYIDLIDSTLTSIAKGDL
                     RVEIDQEFIGDFKSIKISLESIINSFNGDFSEINLSAEQVASASEQVAAGAQALSQGA
                     TEQASSVEELASTINEISDGIKKCADSASLACEVSDQSASQVGFGSRCMDDMMTSMGE
                     ISEKSSEISKIIKTIDEIAFQTNILALNAAVEAARAGQYGRGFAVVADEVRSLAGKSA
                     KAAQNTAILIEEAIKTVENGVRIAKETANALDLVVNGVEKTTNYINGISSAVHSQEVA
                     ITQILSGIEQISIVVQMNSATAEESAAASEEMSAQAQILKELVEKFHLKESEVRESSW
                     V"
     gene            8067..10169
                     /locus_tag="OE968_002993"
     CDS             8067..10169
                     /locus_tag="OE968_002993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheA"
                     /protein_id="HCP7220253.1"
                     /translation="MRQMLDMFIFETSLLLEQLDEIMIQIEKEKVFTHNNINETFRIM
                     HTIKGSASMMGLDNISALAHSVEDLFYAIREGKIEVLDNDLLFDLVFQSLDFIRRDID
                     ELQSRGCISSDYSNFIEGIEEYVSTLELSSSMKSKDNANLESKDEKEVIDSNFEYKED
                     SDVVKIIFEQGCMMENVRAFMLVFELRDYCEFIDFYPKDVETNAESTEYIKSYGFYIQ
                     FVAKEDKAIVYKTIEDNLYVKEYINISKKEIEMKNTSNNDAVENKLKDNNKVSKSYQN
                     NYTEDEIQEDVLNEKTDMEKDSLSEENEHLPISKQSIMSVNLEKLDLLQNIVGEIVIM
                     ESMVVNSVNSTGVDIDNFNKATRQLHKLTDELQDIVMSMRMIQIAGVFQKMHRIVRDM
                     NKKLDKNVELITIGAETEVDKSVIDNLAEPFMHLIRNAMDHAIEPIEERIAKGKEEVG
                     KIVLSAENLGGEAVISISDDGRGIMRDKILAKAKEQGLLKHQSNEYTDDEVNSLIMTP
                     GFSTKESITEFSGRGVGMDIVRKSIEKVGGSIEVKSKQDEGTTFTIKIPLTLSIVEGM
                     KFKVGDSLFTLPISSIRRTFKLTDLNQIITEGNKTELITIYGACIPIIRLHKIYNIQT
                     KVTNLMNGNMIIIENEHKAVCIFVDEIIGNQQVVVKPFPVYFNRFNIKNKGLSGCTIL
                     GDGSISLIIDADSIIEIY"
     gene            10182..10622
                     /locus_tag="OE968_002994"
     CDS             10182..10622
                     /locus_tag="OE968_002994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheW"
                     /protein_id="HCP7220254.1"
                     /translation="MAKDEIIKQVLTFYVNDVIYGIELENVIETIRFQSITYVPCLPT
                     YISGVINLRGRIIPVINMHIKYNLPKADYNERTCIIITKVDEYQVGIIVDKVVDVIHI
                     ENLNLLETTNSNNTNINKDIKEIAKVEDNSILILDIRKFLINSI"
     gene            10658..11461
                     /locus_tag="OE968_002995"
     CDS             10658..11461
                     /locus_tag="OE968_002995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-glutamate O-methyltransferase CheR"
                     /protein_id="HCP7220255.1"
                     /translation="MIKLTDEEFIVLVNYVKKEYGIDLSKKRALIEGRLYNTMIEKKL
                     SSFSQYMNLLFKDKTGNEAINLINRLSTNHTFFMREPQHFEFIQNSILPFWEENNKIR
                     NINIWSAGCSSGEEAYSIAMTLDDYFGYNKELWNIKIIATDISTNSLEKAKRGIYIES
                     NVNNVPELWKKKYFIDNKDGTFKICDKIRKSVIFKPFNLMNDFSYQHFDLIFCRNVMI
                     YFDLKTREELINKFYNATKKDSFLFVGHAEVINRSSTKYKYVKPAIYKR"
     gene            11501..12097
                     /locus_tag="OE968_002996"
     CDS             11501..12097
                     /locus_tag="OE968_002996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheB"
                     /protein_id="HCP7220256.1"
                     /translation="MERFNNMVIAIGASVGGTEAILEIIKDLPKSTPGIVVVQHMPAI
                     FTYMYAQRLDKQCIMNVREAKNNDRVEQGNVLIAPGGYQMKLCTDKQGYYVTCEKGER
                     ISGHCPSVDVLFDSVAEVAGKNSIGIILTGMGYDGANGLLKMKENGSFTIGQDENSCI
                     VYGMPMVAFDRGSVMLQLPLGEISNCLIRHINILKQKD"
     gene            12203..13066
                     /locus_tag="OE968_002997"
     CDS             12203..13066
                     /locus_tag="OE968_002997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 and DUF4163 domain-containing protein"
                     /protein_id="HCP7220257.1"
                     /translation="MKFFKVDTKAKVLRYVFVLTLTIMAVLAIKHDYKYNNLRKDASI
                     NLNSNKEAVTVMSNQSLPKGNTNSKQTLSVSTIGSKTIVKNDEYLESTINMPVITNSN
                     KIVERSTNDKIKNDIFEFYNKSYKEAKQYLKDNPDEKNKFVANVDFELKKNTDSALSI
                     KVRYYTYSGGAHGFYQDIAYNVDMRTGKFLELMDLFKDNTKYKEVIDEEIKRQIAELE
                     KKDEENIGIYNFKGIKENQNFYLQDENLVVYFDLYDITPYAAGIPEFSINKALISSML
                     KPEYVDLFDLK"
     gene            13133..14122
                     /locus_tag="OE968_002998"
     CDS             13133..14122
                     /locus_tag="OE968_002998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HCP7220258.1"
                     /translation="MLLLKKDDIKKVFTMRDAIEADKEAFRIYCEGKSVNPLRTNISV
                     PSQDASMLFMPGYIEELGCGGIKIVSVFPKNAQKGKPVIPATVLLLDGETGEVSAVLD
                     GTYVTQIRTGAASGAAIDVLAKKDSKIGALIGLGGQGEPQLEAMIEARNLDEVRVFSR
                     NKESREKFAEEMNLKLSKYNTKIVAVESSDEAINNADVIVLATPSKQPVLNGNLVKKG
                     ALISAVGSYMPDMQELCPNCLTRASKIFFESTDAVLSESGDILIPLKEGKISKDDFSG
                     DLGNVINGTIPGREDDDEIIVFKTVGIGVQDVVTAKRIYDKAKENGIGIDWKW"
     gene            14214..14825
                     /locus_tag="OE968_002999"
     CDS             14214..14825
                     /locus_tag="OE968_002999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HCP7220259.1"
                     /translation="MKMVKKLILSTIMALVLVLTIGCSNAEEKVKSNFEANLAALEMY
                     KYDEKGISDALTEAEYKQIQTYNSKDKVSMIAQLTPLYGKENAEKIYETIVKLIQGVE
                     KTVTVESSSKDKITLKVVSKALDTSKVMSEANTLVKSYVTDEKNYDKKEKEVQDDMTK
                     MIIDLYNKKPTKEVTTMITYTKKDGKWQPPSNIQKLCEGIYTI"
BASE COUNT         6100 a         1384 c         2742 g         4635 t
ORIGIN      
        1 ttagcaaagt atggaaatta atattacaat aaaaaataaa taatatgtaa agactttaaa
       61 ttaattttaa gtattaagta caaatactaa tttttgatat agaaattgaa taaagtaaat
      121 gataataatc aaatgaatta agatgataat aagtgaattg atatagaaat aagtaaatta
      181 aataagacga taacaagtga gataataata aatgaattga catagcaata agtaaattaa
      241 gtaagacgat aacaaatgag atgataataa gtaaattgat atagaaataa gtaaattaag
      301 taagatgata acaagtgagg taataataag tgaattgata tagaaataag taaattaagt
      361 aagacgataa caaatgagat gataataagt aaattgatat agtaataaat aaattaagat
      421 gataatatcc aaagtgagaa agataataga aagtaaataa aatcatgtaa gaataattta
      481 gataagattc taagatttta tttatttaaa aattagtatg attaatttag attaaataaa
      541 tttaataatt ttagtaggtg gtaatgaatg aaaataaata gattaacaga aataatagta
      601 attctattaa ataaaaaatt agtaacagct aaagagttgg cagatagatt tgaagtttct
      661 acaagaacca tatatagaga tatagaaact ctgtctatgt cgggagtacc agtatatatg
      721 acgaaaggca aaggaggagg gatatcttta atagaagaat attctataga caaggctata
      781 ttgtcaaaaa aagataaaga gagtttaata gtggcactga aaacattaca ggcgactaag
      841 tatccagaaa taaattcagt agtaaataaa attggctcaa tatttggaga gcagaatttt
      901 tcaaactgga ttgaaataga ctttactgaa tggggaagta attttaatga agatgataaa
      961 tttacaaaaa taaaagaagc tattttaagg cgtaatacta taaattttaa ttatgtaaat
     1021 agtttgtcaa gccagacaaa cagaactgtc gaaccactga agcttatgta taagagtaag
     1081 acttggtact tgtatggatt ttgtaaacta aaagatgatt ttaggatatt tagaattagt
     1141 aggataagga atttatctat aaaggatgaa gtattttcaa gaaagataat agaagaagta
     1201 tgtttgaatg attctaaagt aattaaggaa aatactataa cgttgaaatt gaggtttaaa
     1261 gaaaagatgc tttttagagt atttgatgat tttaataagg atttaataac taaaaatgaa
     1321 gatgatacat atgatgtaat tacagaattt cctattggtg aatggattta tggatatatt
     1381 ttatcatttg gtgacaatgt tgaagtactt gaacctaaag atgttaggga taatgtaata
     1441 actagactaa gggagttgtc taaaatttat tcattataat ataatgctag attaaagatt
     1501 ttattaaata tataatatct tgcatttagt atataatatc tcactgagtt taattatatt
     1561 aaaaatatga cataaaggtg tcgtatatta taaattataa ttgaattagt tcaaaataaa
     1621 atatattaat aaaaacaaag tgaggtataa agtatgaatt atgaaatagt agagataaat
     1681 gagaaaatag ttataggaat atcgaaggag actacaaata aagatggaca agcggtaaat
     1741 gatataggtg aattgtggaa aaaatttatg ggcaaaggga tatataatgc tataaagggt
     1801 aaaaagaatg acaagacaat aggtctatat acagattacc agggtgattt tacaagtccg
     1861 tatagctttg ttgcatgttg tgaagtaaat agtaattctg ataaagagaa gaatttagaa
     1921 gaattaaaca ctaataatac tgttggagaa agtattatta gtaaagttat accagcaggt
     1981 aagtatgcaa agtttgttat agtaggaggt caaaaagaag taggagattt ttggtttgag
     2041 ttttggcaaa tggattttga taggacttat ataagtgatt ttgaagagta tcaatgtaat
     2101 acttttgata caaagaaaca agaagttcat atttatatag gaataaagta gatttgttat
     2161 tactatattg aatgaagtat tgagtatagt acatttatta tagatagttt tattatttat
     2221 aactataagc agtaaatctg taaaagattt actgcttttt tagtaattaa tattatcagt
     2281 atcactttga atcttcagac atattcttca tttaatattg tttattgata aatgatactt
     2341 gtaaatataa tgatttgtta tttaatttaa aatatgaaaa aaagtattat aaacacatta
     2401 gaatacttct ggatttatga gtatacaatt tgaaaaatat aaaaaataat gtataaagct
     2461 aaatctaatt taatcgataa tacatataga gaaatataat taagtaaata aacaactatc
     2521 tattagatat tgagaaagtc aaatcctata tgaatctaca gaaatgattt taatgaatct
     2581 gaaaaatttt tttatacaaa cataaaaaag gtataaagtt gttttattat aatttaatta
     2641 cttttgataa ctttttatgt tttatacaat tatattttta ataactcgtc aaaacgccaa
     2701 acatatatta caatagatat ataagttttt ttgttgacaa attatgttaa gagaattaag
     2761 tataatatgg cataaataat tacttttatt tatcaatgaa atgtatttat tgtgtagcga
     2821 aaaatagtca gatagtatag acaataactg aagataaaag cgtttattgt tgtacatatg
     2881 gaggagttag ttttatggaa aataaaattt tgatagtaga tgatgctatt tttatgagaa
     2941 tgataattaa agaagctctg agtaaaagtg gctataataa tttaatagaa gcaaatgatg
     3001 gagaagaagc gtgtaatata tttaaatatg aaaagcctga tttgatgttg cttgatatta
     3061 caatgccaaa aaaagatggt ttagaggtgc taagagaaat aaaaaagttg gattcaagtg
     3121 ctaaggttgt aatgtgctct gcaataggac aagagaatat gattgtagaa gccataaaac
     3181 ttggagcgtt agattttata gtgaagccct tcaaaacaga aacattagtt aaagttgtag
     3241 ataatgcttt aaaataaaag tgtaaatata cactaataca atgaaaagca aataaatgca
     3301 ataataaagg gaggggttta tattataaat tatttagaac ttgatgatgt tcatatagat
     3361 gctcttagag aaattggtaa tataggctct gggaatgcaa ttactgcact tgcatccatg
     3421 ataaatagca atgtagaagt attaatacct atggtcaaga tacttgaata taatgaagcg
     3481 acaaatttgc ttggtggtcc agaaaacaaa gtagtatgta ttttactcga tatgaaaggt
     3541 gatatcaatg gaatgtttat gtttttgttg gatgaatcaa taactcaact tatgctaagt
     3601 tctcttttta ataaagaaga agctttttta gatgagattg aggcaattga aatttcagca
     3661 attaaggaaa taggaaatat tatggcaagt tcatatgtaa atgctattgc atctatgtta
     3721 aacatgacta taagtgtttc aattccagat atatgtattg atatggttgg agctgttcta
     3781 aatgtaccta tgataagatt ttcagatgtt ggtgacaaag tcttatttat agaaaataaa
     3841 tttaaaatga gtgataatta ttttactagt cacattttga tgattccaga aatgagctca
     3901 cttagagaaa tactcgtgag gttgggatta gaagtatgaa tagagagata gtagtgaaca
     3961 ttgcagatat gaagatagcc tatagaccaa atgttttagt tacttatgca cttggttctt
     4021 gtgtaggagt atgtttgata gataaagtag ctggaattgg tggaatgtta cacgttatgt
     4081 tgccatatag taaagatgct attaacattg aaaataagtg taaatttgct gacacaggaa
     4141 taaatgagct cattaaatct atggagaata taggtgcaaa tagaatatat ataaaagcaa
     4201 aaattgctgg aggtgctcag atgtttttag gaagtagcaa ttcagtaatt gcaagtatag
     4261 gacataggaa tgttgaggca gtaaaaaaaa ctcttttagg attaaatatt ccaatattag
     4321 ctgaggacac aggtatgaat tatggtagaa caatacgttt ttacactgag acgggtgaat
     4381 tacttgtaga ttcaataaat aaaggtaaga agaaattata atatatattt catagaaagt
     4441 gtattttagg agggaggtat taaatgagat ttccagatga cccatattta gattatggac
     4501 taattgatga aggaattaag tatctaaagt ttagagtaga tgagcaagac tttggggttg
     4561 aacttgaaaa ggtaatagaa attactggaa atcaagaaat tatatttatt ccagaactac
     4621 ctacatattc taaaggcata ataaatctaa gaggaaaaat cattccgata atagacatgc
     4681 gtttgagact taaaaaagat gaattaatga ctacaaattg catgtatata gtagtaactg
     4741 aaataaagga cttggtagtt ggatttgtgg ttgatagagt tgatgatata gtaagcttag
     4801 aaaaaagtaa aatatcacct ccaccaagag ttactataga atattcggat tattttgtaa
     4861 gtggagttgg agaattagaa ggtaaaataa ttactttact agatttagag aaacttttga
     4921 cagataaaga tgaagtttta atagatgaat taatcaatgg gtttgattgc actatcatgt
     4981 aacataggga tgtagttgga gtgttattat aaaaagattg tgatgagaac atttaagaat
     5041 atagtggtat aattattaag tataaaaatt ttaaatcatt aaaatttgaa tatattatgt
     5101 ttaagagagg tttgtatatg aaaaataagc aacagggaac aattttagtc gttgatgata
     5161 gtgttctgat gtgtgactta atagataaaa cacttacaaa agataatttt aaggttaaaa
     5221 aagcatttaa tgcaatagag gcaaaagaat ttattgaaga atttatacca gacattattt
     5281 tgcttgatat aattttacca gataactctg gttttgagtt ttgtaaggaa gtaaaatcta
     5341 atgctcgtac agcagatata cctataattt ttataacttc aaaaaataca gatacagaca
     5401 tagtaaaagg atttggtgta ggagcaattg actatatggt gaaacctttt agtatgacag
     5461 aattaaaagc tcgtgttata gctcatcttg aagtaaagaa atctcaagat aaattaaaaa
     5521 agataaataa tgaactggaa tcttctcttg aaaaattgaa tagactcgtt gtaagagatt
     5581 atcttacagg tctttacaat aggcgacata taattaatca gcttatggag caaagaagaa
     5641 ttaataaata tagtgaaaca tcaatatccc ttatccttgg tgatattgat gactttaagg
     5701 ttatcaatga tacttatggg catgaagcag gggatttcgt gttaacagta atatcaagta
     5761 taataaaaaa gaattgtaga caaattgata ctgtatcaag atggggtgga gaagagtttt
     5821 tgataatgct cacaaatact ccaatagaag gtgctaagat actttcagaa agaatccgta
     5881 aagagataaa ggagtttgat ttcaactata aagaacataa aataaagtgc actattacat
     5941 taggagtagt agaagtaaac tcaaatatat cattagaaga aaacatatcc ttagcagata
     6001 aagcaatgta tgagggtaaa aacttaggaa aagattgtag cgtagtgagt acaatgaaag
     6061 gattaaaaaa gatataaact tactttatga aggagtacag atatgaaaag agaagtaaag
     6121 ctttctaaat tagcaattgt attgctgatt attatagtat tggctgttct agcagggatt
     6181 ttttcttcta tttcatctta taaagcattt gaaaaagtag aaaaaagtat taatgatatg
     6241 aataatttga ggactcaaag tcagtatata aaagatacaa ctagagagat aagtgatgta
     6301 ttaagaagat atgtatttac aggagaaaaa aagaataaag atatttatga aaaagaatta
     6361 tacggaaaaa caagagaatc agctttaaac aaattagaaa aaattggtct tacaaagagc
     6421 gagtcaaata aaatcttaga agcaaaagaa atatcagatt ctttagtacc aacagaacaa
     6481 agtgcaataa aggcagtcga aagtaatgat aagagtaaag ctcaaagtat aatttttggt
     6541 agtgactata taaactccca agagaaaatg gattctttaa taaatgaatt tcaagaggat
     6601 atagttaccc gttcaaattc caaaattgta gaggtaaaaa aagaattaca aagtctaata
     6661 ttaagaacaa tatttatact ttccctttta ataatattga caataataga atatacagta
     6721 ataaaattaa aaatagtgat tcctattaat aaagtagaaa aacacttttc aagaattgca
     6781 tctggggact taagaacaag tatagacgtt gaagaaagta aatctgaaat agggctatta
     6841 gtgagttctg tcaaaaagat gcaaagtatg cttttaaatt acatagacct tatagacagt
     6901 acattaacta gtattgcaaa aggagattta agagtagaga tagaccaaga atttataggt
     6961 gattttaaat caattaaaat atctttagaa agtataataa actcttttaa tggtgatttt
     7021 tctgaaataa atttatcagc agagcaagtt gcaagtgctt cagaacaagt tgcagcaggt
     7081 gcacaagctc tttcacaggg tgctactgaa caagctagtt cagtagaaga attagcttcc
     7141 acgattaatg agatatcaga tggaattaag aagtgtgcag atagtgctag tcttgcatgt
     7201 gaggtatctg accaatctgc atcacaagtt ggttttggaa gtagatgtat ggatgatatg
     7261 atgacatcaa tgggtgaaat aagtgaaaaa tcgagtgaaa tatcaaaaat aatcaaaaca
     7321 atagatgaga tagcattcca aactaatatt cttgcattaa atgcagctgt tgaagcagca
     7381 agagcaggtc aatatggtag aggatttgca gttgtagcag atgaagttag gtctttggct
     7441 ggtaaaagtg caaaagcagc tcaaaataca gctattctca tagaagaagc tattaaaaca
     7501 gtagaaaatg gtgtcagaat tgctaaagag actgcaaatg cattggactt ggtagtaaat
     7561 ggtgtagaaa aaactactaa ttatattaat ggtatttctt cggctgtaca tagtcaagaa
     7621 gtagcaatta cacagatttt atctggaata gagcaaattt ccatagtagt ccaaatgaac
     7681 tcagcaacag cagaggaaag tgcagcagcc tcagaagaga tgtctgctca agctcaaatt
     7741 ttaaaagaat tagtagaaaa atttcatcta aaggaaagtg aagtaagaga atcatcatgg
     7801 gtttaaatta tgaggtgaat attgaagtaa gagaattatc atgtatttaa attatgagat
     7861 gtatatatat tgaaataaga gaattatcat gtatttaaat tatgagatgt atatatattg
     7921 aagtaagaga ataattgtgt atttaaatta tgaggtacat atagtgagat aagagaatca
     7981 tcaaggattt aaattatgag atgcatatat aatagaaaat tatttgtagg tcgtaggtga
     8041 taaatgtgaa ttatattgaa ccgagtatga gacaaatgtt agatatgttt atatttgaga
     8101 caagtttatt actcgaacaa ttagatgaaa ttatgattca aatagaaaaa gagaaagtat
     8161 ttactcataa caacattaat gaaactttta gaataatgca tacgataaaa ggttcagcat
     8221 ctatgatggg gttagacaat atatctgctt tagcacatag tgtagaagac ttgttttatg
     8281 ctatacgtga aggtaaaata gaagttttag acaatgacct attatttgat ttagtctttc
     8341 aatcattaga ttttataaga agagatatag atgagttaca atcaagaggt tgtatatctt
     8401 ctgattactc taattttatt gaaggaattg aagagtatgt gagtactttg gaattatcaa
     8461 gttctatgaa atcaaaggat aatgcaaatt tagaaagtaa agacgaaaaa gaagtaatcg
     8521 attcaaattt tgaatacaaa gaagactctg atgtagtaaa aataatcttt gaacaaggtt
     8581 gcatgatgga aaatgtgaga gctttcatgc ttgtatttga acttagagat tactgtgaat
     8641 ttatagattt ttatccaaaa gatgtagaaa caaatgcaga gtctacagag tatattaaaa
     8701 gttatgggtt ttatatacaa tttgtagcta aagaggataa ggcaatagtt tataaaacta
     8761 tagaagataa tctctatgta aaagaataca taaatattag taaaaaagaa atagaaatga
     8821 aaaatacatc aaacaatgat gcagtagaaa ataaattaaa agataataat aaagtaagta
     8881 aaagttatca aaataactat acagaagatg agatacaaga agatgtttta aatgaaaaaa
     8941 ctgatatgga aaaagatagt ctaagtgaag aaaatgaaca tttaccaata agtaagcaga
     9001 gtattatgag tgtaaattta gaaaaattgg acttacttca aaatatagtt ggagaaattg
     9061 taattatgga atcaatggtt gtaaatagcg taaattctac aggtgttgat atagataatt
     9121 tcaataaggc aacaagacaa ttacacaagc ttacagatga attgcaagat atagtaatgt
     9181 ctatgcgtat gattcaaatt gctggtgtat ttcaaaaaat gcatagaatt gtacgagata
     9241 tgaataaaaa attagataaa aatgtagagt taataactat aggagcagag acagaggtag
     9301 ataagagtgt aattgataat ttagcagaac cttttatgca ccttataaga aatgctatgg
     9361 accatgcaat agagcctatt gaggagcgta tagcgaaagg taaagaagaa gtgggaaaga
     9421 tagttttatc tgctgaaaat ctaggcggag aagctgtgat aagtatttca gatgatggta
     9481 gaggcattat gagagataag attttggcaa aagctaagga acaaggtctt cttaaacatc
     9541 aaagtaatga gtatactgat gacgaggtca attctttgat tatgactcca ggcttttcta
     9601 caaaagaatc tataactgaa ttttctggaa gaggagtagg catggacatt gttcgtaaaa
     9661 gtattgaaaa agttggaggt tcaattgaag taaaaagtaa acaagatgaa gggacaacct
     9721 ttactataaa aataccatta actctttcta tagtagaggg tatgaagttt aaagttggag
     9781 attcactatt tactttacca atatcatcca taagaagaac atttaaactt acagacttaa
     9841 atcaaataat tacagaagga aataagacag agttaattac aatatatgga gcatgtattc
     9901 ccattataag gttacataaa atatataata ttcaaacaaa agtaaccaat ctgatgaatg
     9961 gtaatatgat aattattgaa aatgagcata aagcagtatg catttttgtt gatgaaataa
    10021 taggtaatca gcaagttgtt gtgaaaccat ttccagttta ttttaaccga tttaatataa
    10081 aaaataaggg tttatcggga tgtacaatac ttggggatgg aagtataagt ttaattatag
    10141 atgcagatag cattatagaa atatattagg ggatttaaag tatggctaaa gatgaaatta
    10201 ttaaacaagt attaacattt tatgtcaatg atgttattta tggaatagaa ttagaaaatg
    10261 tgattgaaac cataagattt caatcaataa cgtatgtacc atgtcttcca acatatataa
    10321 gtggagttat taatttgaga ggaagaataa taccagttat taatatgcat ataaagtaca
    10381 atcttcctaa agctgattat aatgagagaa cttgtataat aattacaaag gttgatgagt
    10441 atcaagttgg aattattgta gataaagttg ttgatgttat tcatatagaa aatctaaatt
    10501 tactagagac gactaattct aacaacacta atattaataa agatataaaa gagattgcga
    10561 aagttgaaga taattctata ttaattttag atattcgaaa gtttttgatt aatagcatat
    10621 agttagttct gataaattag caggaggaag tttttgcatg ataaaactca cagatgaaga
    10681 atttatagtt cttgtaaact atgtaaaaaa agaatatggt attgatttaa gtaaaaaaag
    10741 agcgttaatt gaaggtcgct tatacaatac aatgatagag aaaaaactta gttcttttag
    10801 tcaatatatg aatctattat ttaaagataa gacaggaaat gaagctataa acctaataaa
    10861 tagattgagt actaaccaca cattttttat gagagaacct caacattttg agtttataca
    10921 gaatagtata cttccttttt gggaagaaaa taataaaata agaaacataa atatatggag
    10981 tgcaggatgt tctagtggag aagaagcgta ttcaatagct atgactttgg atgattattt
    11041 tggatataat aaagagttgt ggaacattaa aatcatagcc acagatattt caactaactc
    11101 acttgaaaaa gctaaaagag gtatatacat agaatcaaat gttaacaatg ttcctgagtt
    11161 atggaagaag aagtatttta tagacaacaa ggatggtaca tttaaaattt gtgataagat
    11221 tagaaaaagt gtaattttta agccgtttaa tttaatgaat gatttctcat atcaacattt
    11281 tgatttgatt ttttgtagaa atgttatgat ttattttgat ttaaaaacaa gagaagaact
    11341 tataaataaa ttttataatg ctaccaaaaa agatagtttt ttgtttgtag gacatgcaga
    11401 agtaatcaac agaagtagta ctaaatacaa atatgtaaaa cctgctatat ataaacgata
    11461 aaaaggtatt tttgatatat gattttttgg aggcggtaat gtggaacgtt ttaataatat
    11521 ggttattgct ataggcgcat ctgtaggtgg tacagaagca atacttgaaa ttataaaaga
    11581 cctaccaaaa tcaacaccag ggattgttgt agttcaacat atgccagcta tatttactta
    11641 tatgtatgca caacggcttg acaagcagtg tattatgaat gtaagagaag ctaagaataa
    11701 tgatagagtc gaacaaggaa atgtgttaat tgcacctggg ggttaccaga tgaaattgtg
    11761 tacagataaa caaggatatt atgtaacttg tgaaaaggga gaaagaataa gtggtcactg
    11821 tccatcagta gacgttttgt ttgattcagt agcagaagta gcaggtaaaa attcaatagg
    11881 aataatactt acaggtatgg gttatgatgg agcaaatgga cttttaaaaa tgaaagaaaa
    11941 tggttcattt acaattggac aggatgaaaa ttcttgtata gtatatggaa tgccaatggt
    12001 agcttttgat agaggttctg ttatgttaca attacctctt ggtgaaattt caaactgttt
    12061 gataagacat attaatattt taaaacaaaa agattaattt tttataaata aaaattaatc
    12121 ttttattaaa ttatatggat aaaaaaccct agaaactcca aatataataa gagagattta
    12181 tatttaggag gaaaatgata atatgaaatt ttttaaagtc gatacaaaag ctaaagtttt
    12241 aagatatgta tttgttttaa cattgactat aatggctgtt ttggcaatta aacatgacta
    12301 taaatataat aatttaagga aagatgcttc aattaattta aatagtaata aggaagcagt
    12361 gactgttatg agtaaccagt cattaccaaa gggtaataca aatagtaaac aaactttatc
    12421 agtaagtaca ataggaagta aaacaatagt gaaaaatgat gagtatttag aaagtactat
    12481 aaacatgcct gtaataacaa attcaaataa aattgttgaa aggtctacaa atgataagat
    12541 aaaaaatgac atatttgaat tttataataa atcatataaa gaagcaaagc agtatcttaa
    12601 ggataatcct gacgagaaaa ataagtttgt tgcaaatgta gactttgaac ttaaaaagaa
    12661 tactgattct gctcttagta taaaagtgag atattatact tatagtggtg gagcacatgg
    12721 attttatcaa gatatagcat ataatgtgga tatgagaact ggaaaatttt tagaattaat
    12781 ggacttgttt aaggataata ctaaatataa agaagttata gatgaagaaa ttaaaagaca
    12841 aatagctgaa cttgaaaaaa aggatgaaga aaatatcgga atatataatt ttaaaggtat
    12901 aaaagagaat caaaactttt atttgcaaga tgagaatcta gttgtatatt ttgatttata
    12961 tgatataact ccatatgcag caggaatacc agaattttca ataaataaag cgttgataag
    13021 ttctatgcta aaaccagagt atgtagattt atttgatttg aaatagaaga ttaaattaaa
    13081 tgttatgcta taatatttag catagagact tattaaaatt gggggtataa aaatgctact
    13141 tttaaaaaaa gacgacataa aaaaagtatt tacaatgaga gatgcaattg aagctgataa
    13201 ggaagctttt agaatttatt gtgaaggaaa gagtgtaaat cctttgagaa ccaatatatc
    13261 tgttccaagt caagatgcta gtatgttatt tatgccagga tacatagaag aattaggctg
    13321 tgggggaata aaaattgtat ctgtatttcc taaaaatgct caaaaaggca aaccagtaat
    13381 tccagcaaca gtactattat tagatggaga aactggagaa gttagtgcag tattggatgg
    13441 cacttatgta actcagattc gtactggagc agcctctgga gcagctatag acgtattggc
    13501 taaaaaagat tctaagattg gagctttgat aggtctagga ggacaaggtg agccacaact
    13561 tgaagccatg atagaagcta gaaatttgga tgaggtaaga gtttttagta gaaacaagga
    13621 aagtagagaa aaatttgcag aagaaatgaa cttaaaatta agtaaatata atactaaaat
    13681 agttgcagtt gaatcatctg atgaagccat aaataacgca gatgtgatag ttttagctac
    13741 tccatcaaaa caaccagtac ttaatggaaa cttagtgaaa aaaggagctt taataagtgc
    13801 agtaggttca tatatgccag atatgcaaga gttgtgccca aactgtttaa ctagagcgtc
    13861 taagatattt tttgaatcaa cagatgcagt tttatctgag tcaggagata tattaattcc
    13921 attaaaagaa ggtaagataa gtaaagatga ttttagtggt gatttaggga atgttataaa
    13981 cggaactatt cctggaagag aagatgatga tgagataatt gtatttaaaa ctgttgggat
    14041 aggtgtacaa gatgtcgtaa cagcaaaaag aatatacgat aaagcaaaag aaaacggtat
    14101 tggaatagac tggaagtggt aaaatattca aaataattct atagttagac aaatttatgt
    14161 tataatgttg ataaataaat tttttattat tttaattgag ggaggatgtt tgtatgaaaa
    14221 tggtaaaaaa gttaatatta tctacgatta tggctctagt tttagttcta actatagggt
    14281 gttctaatgc agaagaaaaa gtaaagtcga attttgaagc taatttagct gcattagaaa
    14341 tgtataagta tgatgaaaaa ggaatttctg atgcattaac agaagctgaa tataaacaga
    14401 ttcaaactta taacagcaag gacaaggttt caatgattgc tcaattgaca cctctttatg
    14461 gtaaagaaaa tgctgaaaag atatacgaaa caattgttaa attaattcaa ggtgttgaaa
    14521 agacagtaac agtggaatct tctagtaagg ataagataac tttgaaagtt gtaagtaaag
    14581 ctttagatac tagtaaagta atgagtgaag cgaacacttt agtaaaatct tatgtaactg
    14641 atgaaaagaa ttacgataaa aaagaaaaag aagttcaaga tgatatgaca aaaatgatta
    14701 tagaccttta caataagaaa ccaactaagg aagttacaac tatgattaca tatactaaaa
    14761 aagatggtaa atggcaacca cctagtaata tacaaaagtt atgtgaagga atatatacaa
    14821 tttaatttat tttaaagaca caaaactatc ttttaagcat a
//
LOCUS       DAJMZY010000102        14801 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.103, whole genome shotgun sequence.
ACCESSION   DAJMZY010000102 DAJMZY010000000
VERSION     DAJMZY010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 14801)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14801)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14801
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.103"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            <1..359
                     /locus_tag="OE968_003000"
     CDS             <1..359
                     /locus_tag="OE968_003000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HCP7220260.1"
                     /translation="ILGFVNAPSLFQRVIARSLDAEVDVNIYKKNFDLLYNSLIDMGY
                     SCVKPNGTFYLFPKAPIEDDKKFCNDAKQFNLLLVPGSSFGCPGHFRVSYCVSYDKVK
                     SSLPAFEKLAKLYNLK"
     gene            529..1491
                     /locus_tag="OE968_003001"
     CDS             529..1491
                     /locus_tag="OE968_003001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HCP7220261.1"
                     /translation="MKKGYVYIILTTLFFSSMEISLKTVTNDFNPLQITLSRFFVGGL
                     VLLPFAVKRLRALSLSITKSDLKYFAFLGFMCVVVSMSLYQLAVLNTKASVVAVLFSC
                     NPVFVMLLAYLILKEKIYRHNVISLILEVLGIIVIINPLHTKLTLSGIFLTLSSAIIF
                     SMYTVFGKRKTLKFGGIVVTCFSFIFGSLEMLILVLLTKINFIADILNKNKLHVFANI
                     PIFSGYTLHNMPIMIYVFVFVTGVGYALYFMAMEATSTSLTSLVFFFKPVISPILALL
                     ILKEIIPINMVIGILLIVIGSIISIIPTIITQMHNKHVEALYKE"
     gene            complement(1613..2275)
                     /gene="zmp1"
                     /locus_tag="OE968_003002"
     CDS             complement(1613..2275)
                     /gene="zmp1"
                     /locus_tag="OE968_003002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease Zmp1"
                     /protein_id="HCP7220262.1"
                     /translation="MRPSKKLLIAIISIFLISSVPVSAHADSTTIQQNKDTLSQIVVF
                     PTGNYDKNEANAMVNRLANIDGKYLNALKQNNLKIKLLSGKLTDEKEYAYLKGVVPKG
                     WEGTGKTWDDVPGLGGSTVALRIGFSNKGKGHDAINLELHETAHAIDHIVLNDISKSA
                     QFKQIFAKEGRSLGNVNYLGVYAEEFFAESFAYYYLNQDTNSKLKSACPQTYSFLQNL
                     AK"
     regulatory      complement(2375..2460)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            complement(2646..5564)
                     /locus_tag="OE968_003003"
     CDS             complement(2646..5564)
                     /locus_tag="OE968_003003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021362860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SrtB-anchored collagen-binding adhesin"
                     /protein_id="HCP7220263.1"
                     /translation="MKKGNRKALLISLIMILSMVVSTIYPTVSYASELGENSQIQSGS
                     TNSSTGEEKESDNKKPEQTPEKDKATDNKKPEQTPEEEKPTDNKKPEQTPEEDKSTDN
                     KKPEQTPEGEKPIDNKKPEQIPEEDKSTDNKKSEQALEDEKPLDNKNTEKTPEEDNLL
                     EDENLLKVLEEELNEENEDYGFVVKINNNTIETESMKKISFNLTYTPTSKGIQAGDSI
                     TFKVPDVFNKVNLDYTSECFDKTESNGEYTLTFRELPNGQSVMQGKIGLEAYVKKVDE
                     DTNAKIHIETTGKIESGSGDIDVEIKPGDKTDVPDAKGTLKKLVEGKKSTTVFMPVKN
                     KDINYSIQVNEKQEELKDIILYDELPEGLTLINGSVSVVTSDGKEVSDFNIEQSKNSI
                     SVNFGNIDKSYTVKYKARISDKNAKHGNKYKNVARIESDGKKIQEDDATVSIFDRGDD
                     YLLTKGHSGATNITQVGQVINYQISINDDKSPISNVVITDNIPEGMRLTTSGEAGHDF
                     RVVEIPMNGSWTPWSKEKIANNISYKVEEKRNESGQVDKVITGFTINLSKEEVESKFF
                     IAYTLKVISIEDSYINRAVLDANNSEIDKNDEINFKKNSGLISAKKEVDKKVLNSSDN
                     QIVKYKINMSTYGVYDAGQVNLLDEVNSALEISNIKYSDNLELKKEAGDGKNTIRLVN
                     KYEFKQIKEGEPVQSWVTFDADFTNVKVGETIQNVAQINGSSPPGVETTKQGYAFEAK
                     KVDALDKNVLSGAKFNLEDAFGNIVVKDLVSDEDGIIQSSIKKPGTYYLVEIMAPSGY
                     EKLKDKIKVEIGNKDIGRIVDIGNIENIRQENPPVNPPAPPNTDEPIVNPPVPPSTDK
                     PRKPSSSSDTEDTIVINPPIPPSEDIINPPIPEVLNPPVPPSEEMIETPVKQIIPIPE
                     VVKPSVSEEKNNKVKDDTLVNPPVPPKTGDSTTIIGEILLVIGAIVGLIVLRRNKNTN
                     "
     regulatory      complement(5682..5767)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
     gene            complement(5894..7072)
                     /locus_tag="OE968_003004"
     CDS             complement(5894..7072)
                     /locus_tag="OE968_003004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HCP7220264.1"
                     /translation="MFSKILVKTFIRDSENVQNTDVRNKYGYVAGVVGILSNLLLFVI
                     KVFIGMLTSSIAIMADAFNNLSDMASSAITMIGFKLASKPADKEHPFGHGRIEYLSAL
                     IVAFMVMLVGLQFVKSSIERIVNPIPVKFEVIPLILLIASIMIKIWLSRFNKFMGNKI
                     DSSALKAVSLDALGDVFTSSCVVISFIVARFTNFPIDGYVGIVVSLVILYAGFSLVKD
                     TINPLLGEAPDEEMVNSIIELLLSYKYIIGTHDLIIHNYGVGRCIASIHAEIPSNIDI
                     MEIHEIIDTAEREISEKLDIYLVIHMDPICLEDKEVMSAKKELEEILKKNSLVKSMHD
                     FRIVGKGSKKNLIFDIVVNPSEFSKNMSEDDLKEDITKLVKEINPEYNCVIVVDKDFI
                     "
     gene            7447..7596
                     /locus_tag="OE968_003005"
     CDS             7447..7596
                     /locus_tag="OE968_003005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HCP7220265.1"
                     /translation="MFFISYIYTKSPIEFDTPLQKEAYKILQKLDIDFECVDTDEAIT
                     MEDCV"
     gene            complement(7697..10471)
                     /locus_tag="OE968_003006"
     CDS             complement(7697..10471)
                     /locus_tag="OE968_003006"
                     /EC_number="7.2.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium-translocating P-type ATPase, PMCA-type"
                     /protein_id="HCP7220266.1"
                     /translation="MRYYNKPTKEVLKYLKTNPEIGLDDNEVEERKLRYGLNEFTIKE
                     GRTFWDELGESLTEPMILILIGAAVISSFVGELHDALGILGAIFIGISIGIITEGKSK
                     KAAHALSKLTENIEVKVLRNGKIIKISKNDLVPGDIVYIETGDMIPADGRLIQSINLK
                     LREDMLTGESDDVAKNADAVLDMEVVYSKTEIIEQDAIPAKQVNMVFGGTLVAYGRGI
                     MVVTHTGDKTEMGKIAQNLSNEDQQTPLQIKLGKLGAKIAGISGVIATLLCMFMIIQM
                     QRKGMLILDTSSVLSFLQSLEPAKNAYMVCIALIVATVPEGLPTMINITLAITMQKMA
                     KINALVTKKEACETIGSVSVICSDKTGTLTQNKMMVEVAYVDGKYISGGEYQSNSYFE
                     QNCIVNSTADIEKEDNSFKYIGSATECALLLYHNDKNYNEMRKQTYLISQIPFSSEEK
                     KMSTLIRQEDSDILLSKGAPEVLLKKCSYVQQGKNIVPITPKVEKSILDEIKKLQIKS
                     MRTLGFAYKKMSNSKTEVAMTSEGELNLIGNSRSYMKEDNLVFSGFVGIVDPLREGVK
                     DSIDKAFNAGVDVKMLTGDNINTATAIGNELGLLNDGKKAVEATYIDVLTDKELREEI
                     KGISIVARSKPDTKMRIVSALQKSGEVVAVTGDGINDAPALSQADVGIAMGISGTEVS
                     KNAADIILTDDSFSTIVEGIKWGRGIYENFQRFIQFQLTVNIVAFIIAIISQLTGKDM
                     PFTTIQLLWVNIIMDGPPALALGLEPVRDYVLKRKPINRHSGIIARSMFVNIIINAIL
                     IITIVFTQSAFNILGATSEEQGTVIFSLFAFSALFNALNCREFGLNSTIPNFFKNKLA
                     LQIIVVTGIIQIIFTQVFQSFFNSVSLDFDMWIKIILFASTILLSNEFVKLILRTMKN
                     SRTMNFNSKN"
     gene            complement(10643..11899)
                     /locus_tag="OE968_003007"
     CDS             complement(10643..11899)
                     /locus_tag="OE968_003007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HCP7220267.1"
                     /translation="MLKTTKISDPELYKIVADELVRQEHNIEMIASESTAPTEVLELS
                     GCVFTNKTEEGYPGARFQAGSEEADKLETLAIKRAKEVFGAEHVNVQPYSGSTANYCV
                     YSSILKPNDTVLSMRLDQGGHLTHGSAVNFLHDIYKYEFYGVDPNTGRIDYDALEAKA
                     KECRPKLIIAGASSYPRLIDYERISKVAKEVGAYFMVDMAHVAGLVAAKVIPSPVPYA
                     DFVSSSTTKTFCGPRSGIVLCKAEHAKKLDKGVFPGTLGSIHLNTVAAKAFSLLYLST
                     DKFKKIMEQVVVNAQTLASELISHGFSIVSGGTDNHIVMVDLRSKNLTGKQFEKALEY
                     VGITVNKNVIPDDPQSPFVTSGVRIGLTSISQRGLKEKEVIQIAGIMNKVAENIDNKE
                     VLDECKAEAQELISKFPLYPEGYFED"
     gene            complement(11971..13473)
                     /locus_tag="OE968_003008"
     CDS             complement(11971..13473)
                     /locus_tag="OE968_003008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbgT family transporter"
                     /protein_id="HCP7220268.1"
                     /translation="MRALNVVERAGNKLPDPVTIFLLLCIIVVILSAVISNLGVEEIH
                     PSTKEVVKVVNLLEKEQIQSYLGSIVTNFQSFAPLGLVLVTMLGAGVAEKSGFMEVLM
                     KKGISKVPQKLVTVAIVFAGMLSHTAADVGFIILPPLAALVFLGIGRHPLVGMFAAFA
                     GVAGGFAANVMLSTTDVLLAGFTIPAAQMMDPSYQGNPAMNLYFAFISAIVLTFAGAF
                     VTEKFIAPRFTKYNDSTNDKDIQELSELENKGIKYALLSLLVVVVVIVALCIGDNAFM
                     KDPETGSILSSNAPLMKGIVPIITIIFLTPGLVYGKVSKKIKSDKDLVSMMGSSMSDM
                     GGYIVLAFIASQFINLFNLSNLGTILSITGAKLLAESGIPSYGLIIGFILLSGFINLF
                     VGSASAKWAILAPIFVPMFMLLDFNPALTQIAYRIGDASTNPISPLFPYFPVILAFAR
                     RYDKDIGIGTVISNMIPYSVVFTLIEIIILLLFMGIGIPLGPGGGISYVL"
     gene            complement(13564..14754)
                     /locus_tag="OE968_003009"
     CDS             complement(13564..14754)
                     /locus_tag="OE968_003009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HCP7220269.1"
                     /translation="MHELILISEKYKEDILDFFTDIHMHPELSFKEFRTTKAIKDLLV
                     SLDIEILDLGMETGVVGLLKGKYDGPTVALRGDIDALPIYEEVDIKYKSRYDGIMHAC
                     GHDIHTSCLVGCAYVLSHIRDSLHGNVKFIFQPAEEVNKGAKMLVERGVMENPKVDAI
                     FGLHNHPDIPCGKIGVKLGGLMAAVDTIKIEVNGFGGHGGIPNRTIDPIVASSAIIMG
                     IQTIVSRNISPLESAVISIGTINGGTANNVISEKVDMTGTCRSFSNEVRKKISENLEN
                     IVCEIARGYQATAKLDYLFDLPAVINSKEMYAIACKSVCDLYSEDAIVDPIPSTGGED
                     FSIFMEKAPGFFYWLGVGNKEQDCIYQWHNPKFKADKNSILVGTNVLCQSVINYMDKL
                     KNKI"
BASE COUNT         4562 a         2630 c         1772 g         5837 t
ORIGIN      
        1 gaatacttgg atttgtaaat gctccttctc tttttcaaag ggttattgca agaagtttag
       61 atgcagaagt tgatgtaaat atttataaaa agaattttga ccttctatat aatagtttaa
      121 tcgatatggg atattcttgt gttaaaccta atggtacatt ctatttgttc ccaaaagctc
      181 caattgaaga tgataaaaaa ttctgcaatg atgcaaaaca atttaattta ttattagtac
      241 caggttcttc ttttggttgt ccaggtcatt ttagagtatc atattgtgta tcttatgata
      301 aagttaaaag ttctttacca gcatttgaaa aattagccaa attatataat ttaaaataac
      361 taaatcaaag taattcaaat aattaactac cttagtatag aatacttaca ttctatatta
      421 aggtagttta taattttatg tactatattt tatacatacc atattattcc aatatgcttg
      481 aatattctta tctatagtac taatataaat tacaaggagg tgtttgactt gaaaaaaggt
      541 tatgtttata taatactgac taccttattt tttagttcaa tggaaattag tctaaaaact
      601 gtcactaatg actttaatcc cttacaaata actttatcaa gattttttgt tggcggttta
      661 gtcttactac cttttgctgt aaaaagatta agagctctta gtctttctat tacaaaatca
      721 gacttaaaat actttgcatt tttaggtttt atgtgtgtag tagtaagtat gtcattgtat
      781 caacttgctg ttctaaacac aaaggcatct gtagttgctg ttttgttcag ttgtaatcca
      841 gtctttgtaa tgcttttagc ttacttaatt ttgaaggaaa aaatatatag gcacaatgta
      901 atttcactta tattagaagt tcttggaatt atagttataa taaatccatt gcatacaaaa
      961 ctaactctta gtggaatatt cttaacatta tcttctgcta ttattttttc aatgtatact
     1021 gtatttggta aaagaaaaac cttaaaattt ggtggaatag ttgtaacctg ctttagcttt
     1081 atatttggta gtttggaaat gttgatattg gttttactca ctaaaattaa ttttatcgca
     1141 gatatattaa ataaaaataa gcttcatgta tttgcaaata tccctatttt tagtggatat
     1201 accttacaca atatgcccat tatgatttat gtattcgtat ttgttacagg tgttggttat
     1261 gcgctttact ttatggcaat ggaagctaca tctactagtc ttacatcttt agtattcttc
     1321 tttaaaccag taatatctcc aatactagca ttattaatac ttaaagaaat tatccctata
     1381 aacatggtta taggaatttt attgatagta attggttcaa taatttctat tatacctacg
     1441 ataattactc aaatgcataa taaacacgtt gaagccttgt ataaggagta gtaattgata
     1501 atctatcata gttatacata agacaaaatt tattagattt aaacgcaata taaaagagat
     1561 gctattataa tagcatctct ttatttatat ttattttaaa tttattaaaa ctctatttag
     1621 ctaaattttg caaaaagcta taagtttgtg gacaagctga ttttaactta ctatttgtat
     1681 cttgatttaa atagtaatat gcaaatgatt ctgcaaaaaa ttcttctgca tatacaccta
     1741 agtagtttac attacctaaa gaacgacctt ctttagcaaa tatttgtttg aattgtgctg
     1801 atttagatat atcatttaat actatatggt ctattgcatg tgctgtttca tgtaattcta
     1861 aatttattgc atcatgccct ttacctttgt tactaaatcc tattctaaga gctactgtac
     1921 ttccacctaa acctggaaca tcatcccaag tttttccagt accttcccat cccttaggaa
     1981 ctacaccttt taaataagca tattcttttt catctgttaa ctttccactt aataatttta
     2041 tttttaagtt attttgcttt aatgcattta aatactttcc atctatatta gctaatctat
     2101 ttaccatagc attagcttcg tttttatcgt aatttccagt tggaaaaact actatttgac
     2161 taagtgtgtc tttattttgt tgtatagtag tactatctgc atgtgcactt actggaactg
     2221 aacttattaa gaatattgat attatagcta ttaataattt tttacttggt ctcatattat
     2281 tccctccttt gagttaggcc gggagtaata aatttcaaaa taaaaaagat acccaagagt
     2341 atctttgtat atacaaaaag aaatttttac tcttttcggc aactggctgg catggtttac
     2401 taaactttag cccctatagc tttgcgtgac taggtttccc tagttttgcc tcatttaatt
     2461 ttatatctat attatagctt atatcttttt aattgtctat atccctttgg aacttttttc
     2521 taaaaagtta ttattttttt acataaatct tcaaaaaaaa atatcttcta acaatatttt
     2581 cattattaaa tattgtttta gaagatattt tttaatataa cttatatttt ttataatgtt
     2641 agggtctaat ttgtattttt atttcttctt aatacgataa gtcctacaat agctcctata
     2701 accaaaagta tttctccaat aattgtagta ctatcccctg tttttggtgg tactggtgga
     2761 tttaccaaag tatcatcttt aactttatta tttttttctt ctgacactga tggctttact
     2821 acttctggta ttggaataat ctgtttaaca ggagtttcta tcatctcttc tgatggtggt
     2881 actggcggat tcaatacctc tggtattggc ggatttatta tatcttctga tggtggtatt
     2941 ggtggattta taactatagt atcctctgta tcagatgaac ttgatggttt ccttggttta
     3001 tctgtgcttg gtggtactgg tggatttact attggttcat ctgtatttgg tggtgctggt
     3061 ggatttactg gtggattttc ttgtcttatg ttttctatat ttccaatatc cactattcta
     3121 ccaatatctt tattaccaat ttcaacctta attttatcct tcagtttttc atatccactt
     3181 ggagccatta tctccactaa ataatatgtt cctggttttt ttatactaga ttgaattata
     3241 ccatcttcat cactaactaa atccttaact actatatttc caaatgcatc ttctaaattg
     3301 aacttagcac ctgaaagtac atttttatct aaagcatcca cttttttagc ttcaaaagca
     3361 taaccttgct tagtagtctc tactcctgga ggacttgaac cattaatctg agccacattt
     3421 tgtatagtct ccccaacttt tacatttgtg aagtctgcat caaatgtaac ccaactttgc
     3481 acaggttccc cttcttttat ctgtttaaat tcgtatttat ttactaatct tattgtattt
     3541 tttccatctc cagcttcttt tttaagttca agattatcag aatattttat attagatatt
     3601 tctagagctg agtttacttc atctaaaaga tttacttgtc ctgcatcata aactccataa
     3661 gttgacatat tgattttgta tttaacaatc tggttatcac tactatttaa aactttttta
     3721 tcaacttctt tttttgcgct tattaatcca gaatttttct taaagtttat ctcatcattt
     3781 ttatcaattt cactattatt tgcatcaaga acagctctat ttatatagct atcttcaata
     3841 ctaattacct ttaatgtata agctataaaa aactttgatt ccacttcttc tttactgaga
     3901 ttaattgtaa atccagttat aactttatct acttgcccac tttcatttct tttttcttct
     3961 actttatatg aaatattatt ggcaattttt tctttactcc aaggagtcca gctcccattc
     4021 attggaattt ctacaactct aaaatcatgc ccagcttctc ctgaagtagt taatctcatg
     4081 ccttctggta tattatctgt tataacaaca ttacttattg gtgatttatc atcatttatt
     4141 gaaatctgat agtttattac ttgaccaact tgagtaatat ttgttgctcc tgaatgtcct
     4201 ttagtaagaa gataatcatc tcctctatca aatatactta cagtagcatc atcttcttgt
     4261 atcttcttac catcagattc aatcctagct acattcttat atttattacc atgttttgcg
     4321 tttttgtcac tgattctagc cttatactta acagtatacg atttatctat atttccaaaa
     4381 ttaactgaaa tagaattttt actctgttca atattaaaat cactaacttc ttttccatca
     4441 cttgttacta cacttacaga accatttatc aatgtcaatc cttcaggaag ctcatcatac
     4501 aaaataatat cttttaactc ttcctgcttt tcatttactt gtatactgta atttatatct
     4561 ttatttttaa ctggcataaa tacagtagtt gatttttttc cttcaacaag ctttttaagt
     4621 gttcctttag catctggaac atccgtttta tctccaggtt ttatttctac atctatatct
     4681 ccacttccac tttctatttt tccagtagtt tcaatatgta tttttgcatt agtatcttca
     4741 tcaacctttt taacatatgc ttccaaacct attttacctt gcattacact ttggccatta
     4801 ggtaattctc taaatgtaag tgtatactct ccattacttt ctgttttatc aaagcattca
     4861 cttgtataat ctaaattaac tttattgaat acatctggca ccttaaaagt tattgaatct
     4921 cctgcttgta ttccttttga tgttggagta taagttaaat taaatgatat ttttttcatt
     4981 gattccgttt ctattgtatt gttattaatt tttacaacaa atccatagtc ttcattttct
     5041 tcattaagtt cttcttctaa aactttcaat aaattttcat cttctaatag attatcttcc
     5101 tctggagttt tttctgtatt tttattgtct agtggttttt catcttctaa agcttgttct
     5161 gactttttat tatctgttga cttatcttct tctggtatct gctctggctt tttattatct
     5221 attggctttt ctccttctgg agtttgctct ggctttttat tatctgttga cttatcttct
     5281 tctggggtct gttctggttt tttattatct gttggttttt cttcctctgg ggtctgttct
     5341 ggttttttat tatctgttgc cttatctttc tctggagtct gttctggctt tttattgtcg
     5401 ctttccttct cctctccagt tgatgaatta gttgaaccac tttgaatctg actattctct
     5461 cctaattctg aagcataaga tacagttgga tatattgtag acaccaccat acttaaaatc
     5521 ataattaaac taattaataa tgcctttcta tttcctttct tcatgtaaat ctcacccctt
     5581 taggttacct ataatttata atctaatctt ccattaatat cgtatataaa gtaattttta
     5641 ctaaaaaatt atacaaaaaa agctatgaaa ataaataaat ttatattcat agccggttgc
     5701 accactgact cagtatatcc ataaggtgcc caataataga atatacttca acatctctat
     5761 aatatttcat aaaaacaatt aaaattgctt tatttatatt aaaaatacaa ttatatactt
     5821 ctattatatt atgcctctat actattgtct atccttttta cattttttac cttatgatga
     5881 gattaattaa taattaaata aaatccttat ctacaacaat tacacaatta tattcaggat
     5941 ttatctcctt aactaatttt gttatatctt cttttaagtc atcttctgac atgtttttgg
     6001 aaaattcgga aggattaact actatatcaa atattaaatt cttcttgctt ccttttccaa
     6061 ctattctaaa atcatgcata gattttacaa gactattttt cttaagtatt tcttcaagtt
     6121 cttttttggc tgacataact tctttatctt caagacatat tgggtccatg tgaattacta
     6181 gatatatatc taatttttca gatatttctc tctctgcagt atctataatt tcatgtattt
     6241 ccattatatc tatgttggat ggaatttctg catgtataga tgcaatacat ctaccaactc
     6301 catagttatg aataattaaa tcatgtgtac ctattatata tttataagat aacaatagct
     6361 ctataataga atttaccatt tcttcatctg gtgcttcccc taaaagagga tttatagtat
     6421 cttttacaag agagaaacca gcataaagta tcactaatga tactacgata ccaacatatc
     6481 catctatagg aaaattagta aatctagcta caataaatga tataactaca cagcttgaag
     6541 taaatacatc tcctaaagca tcaagtgaaa ctgcttttaa ggctgaagaa tcaattttat
     6601 ttcccataaa tttattaaaa cgactcaacc agattttaat cattatagat gcaattaaaa
     6661 gtataagtgg tattacttca aattttacag gaattggatt tactatcctt tctatagatg
     6721 actttacaaa ttgaagtcca accaacatca ccataaatgc tactattaat gctgataaat
     6781 actctattct tccatgacca aaagggtgtt ctttatcagc tggcttactt gctaatttaa
     6841 aacctatcat agttattgct gaagatgcca tatcagaaag attattaaat gcatcagcca
     6901 ttatagctat actagatgtg agcattccta tgaatacctt tatcacaaat aaaagtaaat
     6961 tggataatat acctactaca ccagctacat aaccatactt atttctaaca tctgtatttt
     7021 gaacgttttc gctatctctg ataaatgttt tgactaggat tttggaaaac atgaaactta
     7081 cctccctgcc ctttatttta ttaacaaatt ttataatcta tatctttatt tatgataaca
     7141 taatttatat ataaaattct taaaaatcac tctacttcag taaaatatta ttctatatat
     7201 ctatttagat acgaatttta tatttagtaa agtttttatg gcttagtgtc tgtttaatag
     7261 attctatata agtttttaca aagattattt attatgataa tatcattttt cccaagtatt
     7321 acttagaata tgattttttt gttttgtctg tacatatttt aaatttatac tatatttatc
     7381 tatattttat aaccttatga tacactataa ctataagttt ttaaatggaa aggaatgaaa
     7441 taaatcatgt tttttatcag ttatatttac acaaaatcac ctattgaatt tgatactcct
     7501 ttgcaaaaag aggcatacaa aatattacaa aaattagata ttgactttga atgtgttgac
     7561 acagatgaag caattacaat ggaagattgt gtttagatta ataaaaaatt aaatatgaaa
     7621 atggtaatat aaaacaacat taaacaaaca aaaaccgcaa agttacaata tatagtactt
     7681 tgcggtttca taggaattaa tttttactat taaagttcat agttctacta tttttcattg
     7741 ttctaagaat tagctttaca aattcatttg acaataggat agtggatgca aatagtatta
     7801 tctttatcca catatcaaag tccaaagaaa cagaattaaa gaaactctgg aacacttgtg
     7861 taaatattat ttgaattatc cctgtaacta ctattatttg caatgccagt ttatttttaa
     7921 agaaatttgg tattgtacta tttaaaccaa actctctaca atttaatgca ttaaaaaggg
     7981 cactgaatgc aaataaagaa aatataacag taccttgttc ttctgatgta gctcccaata
     8041 tattaaaagc tgattgagta aatacaattg taattataag aatagcattt ataataatat
     8101 ttacaaacat agacctagct attattccag aatgtctatt tattggtttt cttttcaata
     8161 cataatctct aacaggttct aatcctaatg ctagggctgg aggaccatcc attattatat
     8221 ttacccataa taattgtatt gtagtaaatg gcatatcctt accagtaagt tgagatatta
     8281 tagcaattat aaatgctact atatttacag taagctgaaa ctgtataaat ctttgaaagt
     8341 tctcatatat acctcttccc cattttattc cctctactat agtactaaag ctatcatcag
     8401 tcaatattat atctgctgca tttttagata cttctgttcc tgaaataccc attgcaattc
     8461 caacatctgc ttgactaagt gctggggcat catttatacc atcacctgtt acagctacaa
     8521 cttcgccact tttttgaagt gctgaaacta ttctcatttt tgtatctggt ttacttcttg
     8581 caacaataga tattcctttg atttcttctc tcaattcttt atctgtcaat acatctatat
     8641 atgttgcttc aactgccttt ttcccatcat ttaataatcc taattcattt ccaatagctg
     8701 ttgctgtatt tatattatct cctgtaagca tttttacatc tactcctgca ttaaatgctt
     8761 tatcaatgga atctttgacc ccttctctca atgggtccac tattcctaca aatccactaa
     8821 aaactaaatt atcttccttc atataacttc ttgaatttcc tattaaattc aattcacctt
     8881 ctgaagtcat tgcaacttct gttttagaat tactcatttt tttataagca aatcctaatg
     8941 ttctcataga tttaatttgt aacttcttaa tctcatctaa aatacttttt tctacttttg
     9001 gagttattgg aacaatattt tttccttgtt gtacataaga acattttttt aataatactt
     9061 ctggagcacc ttttgaaagt aatatatctg aatcctcttg acgaattaat gttgacatct
     9121 tcttttcttc tgagctaaat ggtatttgtg atatcaaata cgtttgtttt ctcatttcat
     9181 tatagttctt atcattatga tataaaagta atgcacactc tgttgcgctt cctatatatt
     9241 taaatgaatt atcttctttt tctatatctg cagttgaatt tactatacag ttttgttcaa
     9301 aatagctatt actttgatac tctcctccac ttatatattt accatcaaca tatgctacct
     9361 ctaccatcat tttgttttgt gttaaagtcc ctgttttgtc ggaacatatt acagaaacag
     9421 aacctatagt ttcacaggct tctttctttg ttactaatgc atttatcttt gccatctttt
     9481 gcattgttat agctaaggta atatttatca tagttggcaa accttctgga acagttgcaa
     9541 ctattaatgc aatacaaacc atatatgcat ttttagcagg ttctaatgat tgtaagaaag
     9601 ataatacact gcttgtatct aaaattaaca taccttttct ctgcatctgt ataatcataa
     9661 acatacataa taaagtagct attacgcctg atattcccgc tattttagca cccaacttcc
     9721 ctaatttaat ttgaagtgga gtttgctggt cttcatttga taaattctgt gctatcttac
     9781 ccatctctgt cttatcacca gtatgagtga caaccattat gcccctacca tatgctacaa
     9841 gagtccctcc aaataccata ttgacttgct ttgcaggtat tgcatcctgt tcgattattt
     9901 ctgttttaga ataaactact tccatatcta atacagcatc agcattctta gctacatcat
     9961 cagattctcc tgttagcata tcttctctaa gtttcaaatt tatagactgt ataagtcttc
    10021 catctgctgg tatcatatcc ccagtttcta tatatacaat atctcctggt actaaatcat
    10081 tttttgatat tttaattatc ttcccatttc taagcacctt tacttctata ttttctgtta
    10141 attttgacag ggcatgagct gcttttttag attttccttc agttattatg cctatagaaa
    10201 ttccaataaa aatagcccct aaaataccta atgcgtcatg taattctccc acaaaagaac
    10261 ttattactgc tgctcctatg agaattaata tcataggttc tgtcaaactt tctcccaact
    10321 cgtcccaaaa tgttctacct tcttttatag taaattcatt taatccatat ctaagcttcc
    10381 tttcttctac ctcattatca tcaagtccaa tttctggatt tgtttttaag tattttaata
    10441 cttctttggt aggtttatta taatacctca taactttatc ccccttgtta attatctata
    10501 aggaattata tgcttatgat agcttgtata ttacttttca aaaaaaataa ggtgttgatt
    10561 aatcaacacc ttatagtggt tatatattat taaattttat gttacaggct ttataaattg
    10621 tgagctatac aaatcaaaat atttaatctt caaaataccc ttctggatat aatggaaact
    10681 tagatataag ttcttgtgcc tctgctttac attcatctaa tacttcttta ttatcaatat
    10741 tttctgctac cttattcatt atccctgcta tctgtataac ttctttttct ttcagacctc
    10801 tttgagatat tgatgtaaga cctatacgaa caccactagt tacaaatggt gattgtgggt
    10861 cgtcaggtat aacattttta ttaactgtta ttcctacata ttcaagagct ttttcaaatt
    10921 gttttcctgt aagattctta cttcttaagt caaccattac tatatgatta tcagtacctc
    10981 cacttacaat actaaaacca tgtgaaatca gttcagaagc tagagtctga gcatttacta
    11041 caacttgctc cattatcttt ttaaatttat ctgtacttaa atataatagt gaaaaggctt
    11101 ttgctgcaac tgtattaaga tgtatagacc ctaatgttcc tggaaaaaca cctttatcga
    11161 gtttctttgc atgttctgct ttacaaagta caataccact tcttggtcca cagaaagtct
    11221 ttgtcgtaga tgaagaaaca aaatctgcat aaggtacagg actaggtatt actttcgctg
    11281 cgactaatcc tgcaacatgt gccatatcta ccataaagta agctcctact tcttttgcaa
    11341 cctttgatat tctttcataa tctattaatc ttggatatga acttgcccct gcaattataa
    11401 gttttggtct acattctttt gcctttgctt caagagcatc ataatctata cgtccagtat
    11461 ttgggtctac cccataaaat tcatatttat aaatgtcatg taaaaaatta actgcgctac
    11521 catgtgtcaa gtgtccacct tggtcaagac gcatacttaa aacagtgtca tttggtttta
    11581 atattgatga atatacacaa tagttagctg tagaacctga atacggttgt acgtttacat
    11641 gttctgctcc aaatacttct tttgcacgtt ttattgctag ggtttcaagt ttatctgctt
    11701 cttcagaacc tgcttgaaaa cgagcccctg gatagccttc ttctgtttta tttgtaaata
    11761 cacatccact taattcaagt acttctgttg gtgctgtact ttcagaagct atcatctcaa
    11821 tattgtgttc ttgtctaacc aactcatcag ctacaatctt gtataactct gggtctgaaa
    11881 tttttgttgt ttttaacata ataatcctcc tcttaattaa agaatatatt ttattagttt
    11941 aatcttcatt gataaattta ttataacggt ctataaaacg taagatattc ctccaccagg
    12001 tcctaatggt atgccaatac ccatgaatag taacaatatt attatttcta ttaatgtaaa
    12061 taccactgag tatggaatca tattcgatat gacagtacct atacctatat ctttatcata
    12121 tcttctggca aaggccaata taactggaaa atacggaaaa agtggactta ttggatttgt
    12181 tgaagcatct ccaatacgat aagctatttg agttaatgct ggattaaagt ctagtagcat
    12241 aaacatggga acaaatatag gtgctaaaat cgcccatttt gcagaagcac ttcctacaaa
    12301 taaattgata aatccagata gcaatataaa tcctattatc aatccatagc taggtattcc
    12361 cgactctgct agtaattttg ctcctgttat tgataaaatt gttcctaagt tactaagatt
    12421 aaataaatta ataaactggg atgctataaa tgctaggact atatatccac ccatatcact
    12481 catactacta cccatcatag atactaaatc tttgtcactt tttatcttct tacttacttt
    12541 tccatacact aatcctggag ttaaaaatat aatagtgatt ataggaacta tacctttcat
    12601 taaaggtgca ttactagata gtatagaacc agtctctgga tctttcataa atgcattgtc
    12661 acctatacat aaggcaacta tcactactac tacaactaac aatgataata aagcgtattt
    12721 tataccctta ttttcaagtt cactcaattc ctgtatatcc ttatcatttg ttgaatcatt
    12781 atattttgta aaacgaggag ctataaattt ttcagttaca aatgctcctg caaaagttaa
    12841 aactatcgct gatataaaag caaaataaag attcattgct ggattgcctt ggtaagatgg
    12901 gtccatcatt tgagctgctg gtattgtaaa tccagctaac aatacatctg tagtactaag
    12961 cataacattt gctgcaaatc cccctgcaac acctgcaaaa gctgcaaaca tacctacaag
    13021 aggatgtctt ccaattccta aaaacacaag tgctgcaagt ggtggtaata ttataaatcc
    13081 tacatctgct gctgtatgtg acaacatacc tgcaaatacg attgctacag ttacaagttt
    13141 ttgtggaact ttacttatac cctttttcat taacacttcc ataaatccag atttctcagc
    13201 aacacctgct ccaagcattg taaccagtac taatcctaaa ggagcaaatg actgaaagtt
    13261 tgtaactatg ctacctaaat atgattgaat ctgctctttc tctagtagat ttactacctt
    13321 tacaacttct tttgtagaag gatgtatttc ttctactcct aaattagata taactgctga
    13381 caatattaca acaattatac atagtaataa aaatatggtt actgggtctg gaagtttatt
    13441 tcctgctctc tctacaacat ttagtgccct catcaataat ccactatctt tgtttttttc
    13501 ctgtgaatta attttcctca aactaatacc ccctcataaa ctttatctcc agaatgctct
    13561 atcttaaatt ttatttttta atttatccat ataatttata acagactgac atagtacatt
    13621 tgtacctacc aatatagaat ttttatcagc tttaaattta ggattatgcc actgatatat
    13681 acaatcttgt tctttgttgc ctacccctaa ccagtaaaaa aatcctgggg ctttttccat
    13741 gaatatagaa aaatcttccc ctcctgtaga aggtattgga tcaactatag catcttctga
    13801 atacaaatca cacacagact tacaagctat tgcgtacatc tctttactat ttataacagc
    13861 tggtaaatca aataaataat ctagctttgc agttgcttga tatccacgag ctatctcaca
    13921 aactatattt tctaaatttt ctgatatttt ctttcgtact tcattactaa agcttctaca
    13981 tgtgcctgtc atatctacct tttctgaaat tacattattt gcagtccctc catttatagt
    14041 acctattgat ataacagctg attctaatgg acttatgttt ctgcttacta tggtttgaat
    14101 acccattata attgcacttg atgctactat agggtctatt gttctgtttg gtatacctcc
    14161 gtgacctcca aatccattta cttctatctt aatagtgtct actgctgcca ttaacccacc
    14221 taacttaaca cctatttttc cacaaggtat atctggatga ttatgaagtc caaatatagc
    14281 atcaactttt ggattttcca ttactcctcg ttccactaac atcttcgcac ctttattgac
    14341 ttcttcggct ggttgaaata taaactttac atttccatga agactatctc taatatgaga
    14401 caatacatat gcacatccta caaggcaaga cgtgtgtata tcatgcccac atgcatgcat
    14461 tataccatca tatctggatt tatacttaat atcaacctct tcatatattg gcaacgcatc
    14521 aatatctcct cttagtgcta ctgtgggacc atcatacttc ccttttaata atccaacaac
    14581 gcctgtttcc attcctaaat ctaatatttc tatgtctaaa ctcactaata aatcttttat
    14641 agcttttgta gtcctaaatt ctttaaaact taattcgggg tgcatatgaa tatctgtaaa
    14701 aaaatctaaa atatcttctt tatacttttc tgagattaaa ataagttcat gcatactaac
    14761 acctctccaa aattttattt ttttattttt tataatttaa c
//
LOCUS       DAJMZY010000103        14353 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.104, whole genome shotgun sequence.
ACCESSION   DAJMZY010000103 DAJMZY010000000
VERSION     DAJMZY010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 14353)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14353)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14353
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.104"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            <1..412
                     /locus_tag="OE968_003010"
     CDS             <1..412
                     /locus_tag="OE968_003010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220270.1"
                     /translation="GFKKTKPCNKIYKIIIVLILTCILFKSFMYVKSINELEDYISQN
                     KLVDKSRHTLPTTDKTREKFSKIKLNEIKKIYETIGINIITKISIDKNKLEIEGVCSD
                     LDVLNNLRKIKYIKYYYIDSIVRDGEYYRFRIKS"
     gene            427..1011
                     /locus_tag="OE968_003011"
     CDS             427..1011
                     /locus_tag="OE968_003011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220271.1"
                     /translation="MRLNNREKNLLKILLILVIILASDIAVSYLEENLTSLKNEKQNI
                     INKINNQDNYQIKDNKHIDDKYIESVESNKNEELKNNFNNSFLDKKTNKDIVLLVENE
                     LRDIVNVEYINQESSLDNHNKKQVNLEIKVNGELANLLKLEGVMKKLRLNNKLEKIEI
                     NKLKVNNFDVQNIPNEYKQEKDNIVECKMTVRVI"
     gene            1264..2301
                     /locus_tag="OE968_003012"
     CDS             1264..2301
                     /locus_tag="OE968_003012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SEC-C domain-containing protein"
                     /protein_id="HCP7220272.1"
                     /translation="MLGRNELCPCGSGKKYKKCCLNKDIVSERACRKTELSQKQYTDL
                     YSKLYDYSRQDKFKEECEKAKEMFYIMQNDSVNEKFERFFNTYLIQDHIMENKKVMTV
                     GFLEENGANLSQSEVSILKSMFESYVSIYEVKEVSAGKIVLKDCLSGNELCTEDVKLL
                     RSFKIGSCMIARIVDIEGTNILIDITISISNEVKDIILKDIMNLFNQYQDVYKDMKSF
                     LIYHTHILYKYIQQLLDPSIAEYLKRERDKNDTKVNSENELAEEECKVLDTLKENVEK
                     ENIDACIEFWNEYKKNHENIKGAENGWAAAVEYYVKKEAGQPITQVQISKKYDISSST
                     LGKRYKDLKIS"
     gene            2382..2747
                     /locus_tag="OE968_003013"
     CDS             2382..2747
                     /locus_tag="OE968_003013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220273.1"
                     /translation="MSLSLGNAIAVSTNFIKSNPAVPVYNGEEIYAVIYHIEIGYNNG
                     VSPDTKQYIIIDYKEFDLSMDKKNELINIAKEYCKSKGIVENENLEINLLDNEEAENF
                     LEKVFNNMKVIRGLITKKG"
     gene            2752..3069
                     /locus_tag="OE968_003014"
     CDS             2752..3069
                     /locus_tag="OE968_003014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220274.1"
                     /translation="MDYIGIENITPYENTYEFSVYEYDDEITLGSEKLYVCELRVVLI
                     KVNSLYVERLHKSVEAMVLVKNLKKDLDKTLVVNKIKNFVLDEIWVENLVKENIEVIF
                     VES"
     gene            3117..4721
                     /locus_tag="OE968_003015"
     CDS             3117..4721
                     /locus_tag="OE968_003015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220275.1"
                     /translation="MLRVSNVKLGIDKDISLLKDVILKKLKIKEKNLVKYSIYKESID
                     ARKKGKMEFVYSVDVEVKDENKILNSKIKDVTKIKEIRYVNVPVGDKKLKNNPLVIGS
                     GPAGLFAGLLLAQMGYEPIILERGLDVDSRTKDISDFWTTRKLKNNSNVQFGEGGAGT
                     FSDGKLTTRIKDIRCRKVLEELVQFGAPDEILYSHKPHVGTDILKNVVKNIRNEIISL
                     GGQVRFNSKVTDIVVSNDSIQSVIINDTEKIDTDTIILAVGHSARDTYEMLYSRGIKI
                     VQKPFAIGARVEHPQDLINKAQYKDFYNHPRLGAADYRLIEHVSNGRTAYTFCMCPGG
                     SVIASASNDFEIVTNGMSEHARDKINANSAFLVNVTPEDFKSDNPLAGVHFQQKYEKL
                     AFELGGKNYNAPVQLVGDFINNKTSLNLGSVEPSYRPGYTLTNLSECLPSFVTETMRE
                     AFISLDKKLNGFAMYDAVLTGVETRSSSPIRIVRDENTLESVSIKNLYPCGEGAGYAG
                     GIVTAAVDGIKCAEKIIQKYTNNTKI"
     gene            4845..6473
                     /locus_tag="OE968_003016"
     CDS             4845..6473
                     /locus_tag="OE968_003016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HCP7220276.1"
                     /translation="MNIIISLMGGLGLFLYGMNLMGEGLQKSAGTKLKKIIKLLTSNL
                     FMGVLVGTGVTAVIQSSSATTVMVVGFVNAGIMTLKQAIGVIMGANIGTTVTAQLVSF
                     DLTGMAPVALGVGIILYLFGNKPRIKNIAEILIGFGILFTGMDFMKMAVEPLRDYQGF
                     TDLLVTFGRYPLLGLLLGFGITAIIQSSSASMGMLVALAAEGLVPLSAALPILYGQNI
                     GTCVTSLLSSIGANKNARRAAMMHLIFNVLGTVIFLIFLNKPVVSMVTSWDPSNVARQ
                     IANTHTLFNIISVLILLPFTSLIIKLAIKLVPDRAGDIDEDETKTIKYIDDRMIETPS
                     IALANTIKEALRMGEKAKESLNASMEALVEHSTEKIDKTYRRERLINDLQKAILNYLL
                     KLSKAALDDDSREVVDTLFNTVNDIERIGDHAKNIAELSQVAIDSNIYFSEEGQSELD
                     VMYNRVVSAYTYALESMRSDNVDLACKVIKIEEQVDIMEKSCRANHMYRLNNNLCSIE
                     NGVIYLDVISNLERISDHAVNIAQQVIAKRLGND"
     gene            6738..8087
                     /locus_tag="OE968_003017"
     CDS             6738..8087
                     /locus_tag="OE968_003017"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HCP7220277.1"
                     /translation="MGKINFDYSKATEFFCQNEIDVMQPYVDVAHDMLHNKTGLGNTF
                     LGWIDLPKNYDKEEFDRIKKSADKIKSDSDVLLVIGIGGSYLGSRAAIDMVSHSFRNG
                     LKKEQRKAPEVYFVGHNISSTYIMDLLDIIEGKDISVNVISKSGTTTEPALAFRIFKD
                     YLEKKYGKEEARKRIYATTDASKGALRQLATEEGYETFVIPDDVGGRFSVLTAVGLLP
                     IAAAGLDIDAMMKGANDAREAFQNPDLKSNDSYRYAVARTILHRKGKDVELLVNYEPQ
                     LHYVSEWWKQLYGESEGKENKGLFPASVDFSTDLHSMGQYIQDGKRLLFETVLNVENC
                     KRNITISSEEVDLDGLNYLAGKTVDFVNHKAFEGTLLAHTDGKVPNLVINIPQLDEYN
                     FGYLVYFFEKACGISGYLLGVNPFDQPGVEAYKKNMFALLGKPGYEKEKEELEKRLK"
     gene            8243..9322
                     /locus_tag="OE968_003018"
     CDS             8243..9322
                     /locus_tag="OE968_003018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HCP7220278.1"
                     /translation="MSRRKKGISLVILVAIISSILSSFLTIILVKDNLVSKSTGSSTP
                     IVVNDDGKSQNIYQAVAEKATPSVVGITTTSVDTSNMFAIPTETQGVGTGIIVDSNGY
                     ILTNSHVISDGQATSVNVLFNDGSTTSGKVVWFDQQLDLAIVKVDKTGLTPAEFADSD
                     KVKVGDISIAIGNPLGLDFQKTVTQGIISGLDRTIQTEKTNMTGLLQTDASINAGNSG
                     GPLLNQKGQVIGINTAKASQAEGLGFAIPINTAKSIVEEVIKNGKYEKVTLGIKGTDV
                     SNYEAATGTKLSTDKGVYVAEVISGSSAEKAGVKVGDIITKVGDTDITGMNDLNKKLY
                     TFSKGASTKITVNRGGKAVTINVNF"
     gene            9667..10575
                     /locus_tag="OE968_003019"
     CDS             9667..10575
                     /locus_tag="OE968_003019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HCP7220279.1"
                     /translation="MNPLVINLQKCSIHDGPGIRSTVFFKGCPLECVWCHNPESQTYT
                     KQVLYNEERCSKCEACINICPHKAIYKGETKICLDQDKCEFCETCLDYCVNNAREIVG
                     QEYSVRDLVKEIEKDRIFYEESGGGVTLSGGEVMAQDMDFICGVINMCKSKGIHVAID
                     TCGYAKSENYERVAKCADLFLYDIKLIDEDKHIKFTGKSNDLILKNVKILSELGANIN
                     IRIPLIVGVNVDDENLEVKKMIEFLKPLNIQAVSLLPYHNIGKHKYDKIYKKYEGEEL
                     QRPSEEKLEEIKRLFEASNFNTKIGG"
     gene            10580..12949
                     /locus_tag="OE968_003020"
     CDS             10580..12949
                     /locus_tag="OE968_003020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HCP7220280.1"
                     /translation="MARGTFERTKKLREESINAEPHISIERAVLMTEAYKKYEGSVEI
                     PVLRALSFKHYIENRTLSINDGELIVGEKGDSPNGAPTYPEICCHTMEDLEVMHNRDI
                     INFSVSEEARKIHKEEIIPFWKKRQTRDKIINAMTPEWLAAYEAGMFTEFMEQRAPGH
                     TVCGDTIYKKGFLDLKKDIEARLKELDFLNDLDAYNKKADLEAMAIACDAMVILGKRY
                     AEKARQMAEEETDEAKKQDLLLIAETCDVVPAHKPETYHQAIQMYWFVHIGVTTELNI
                     WDAFTPGRLDQHLNPFYERDVENGILDRDRAQELLECLWVKFNNQPAPPKVGITLKES
                     STYTDFANINTGGINPDGQDGVNEVSYIILDVMDEMKLIQPSSNVQISKKTPQKFLKR
                     ACEISRKGWGQPAFYNTEAIVQELMEAGKTIEDARLGGTSGCVETGCFGKEAYVLTGY
                     MNIPKILELTLNNGYDPISKKQIGIETGDPRNFQSYEELFEAFKKQLHYMIDIKIEGN
                     AVIENICAKHMPCPLMSTIVDDCIEKGKDYQRGGARYNTRYIQGVGIGTITDSLTAIK
                     YNVFDKKKFDMDTLLKALDANFEGYEAILNLVSNKTPKYGNDDDYADEIMQEIFNAYY
                     NEVTGRPTVCGGEYRVDMLPTTCHIYFGEIMGASPNGRLCAKPVSEGISPEKGGDTNG
                     PTAVIKSCAKMDHIKTGGTLLNQRFAPSVVQGEKGLDNMANLVRAYFNMDGHHIQFNV
                     FDKNVLLEAQKNPQDYKDLIVRVAGYSDHFNNLSRTLQDEIIGRTEQTF"
     gene            13274..14077
                     /gene="proC"
                     /locus_tag="OE968_003021"
     CDS             13274..14077
                     /gene="proC"
                     /locus_tag="OE968_003021"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HCP7220281.1"
                     /translation="MKTLGFIGSGNMGSAMIGGIVQSGLVKAEDITVSDLSQVALDKV
                     KEEFGVNTTTDSKVAVTNSDVVIVALKPNICEKALTPLKELIDANKIIVSIAAGKTIE
                     SLESFIGSDKKIVRVMPNTPALVGEGMSALCKNSNVTDEELNMIKALFESFGEAEIVS
                     EYLMDTVTGISGSSPAYVFMFIEAMADAAVLAGMPRQQAYKFASQAVMGSAKMVLETG
                     KHPGELKDMVCSPAGTTIEAVKVLEEEGFRAAVIKSIVACIDKSKDMSK"
BASE COUNT         5879 a         1467 c         2633 g         4374 t
ORIGIN      
        1 tggatttaaa aaaactaaac catgtaataa aatctataaa ataataatag tcttaatttt
       61 aacgtgtatt ttatttaaat catttatgta tgtgaaatct ataaatgaac ttgaagatta
      121 tataagtcaa aataagctag tggataaatc aagacacact ttaccaacaa cagataaaac
      181 tagagagaaa ttttctaaaa taaaacttaa tgaaataaaa aaaatatatg aaacaattgg
      241 aataaatatt attactaaaa tatcgataga taaaaataag ctagagattg aaggtgtgtg
      301 tagtgattta gatgttttaa acaatctaag gaaaataaag tacataaaat attattacat
      361 agacagtatt gtaagagatg gagaatatta tagatttaga ataaaaagtt agatgggtga
      421 ttatttttga gattaaataa tagagaaaaa aatctactta aaatattgtt aatattagtt
      481 attatattgg caagtgatat agcagtaagt tatttggaag aaaacttaac tagtttgaag
      541 aatgaaaagc aaaatataat aaataaaata aataatcaag ataattatca aataaaggat
      601 aataagcata tagatgataa atatatagaa agtgttgaat caaataaaaa tgaagaatta
      661 aaaaataatt ttaataactc atttttagat aaaaaaacaa ataaagatat agtgttatta
      721 gtagaaaatg aactgagaga tattgtgaat gtagaatata ttaatcaaga aagtagttta
      781 gataatcaca ataaaaaaca agttaattta gaaataaaag ttaatggaga acttgcaaat
      841 ttgttgaaac ttgaaggtgt aatgaagaag ttaagactaa ataataaact tgaaaagata
      901 gaaattaata aattaaaagt caataatttt gatgttcaaa atattccaaa tgaatataaa
      961 caagaaaaag acaatattgt tgaatgtaaa atgacagtta gagtcatata acaaaaaaga
     1021 atagataaag taaaaaacta ttatcaatta ataaaatttt atagaggaat tagttttacg
     1081 ataattcatt tctacaagag ggattgttga tgattttatc gaaatcctaa ttaaagttaa
     1141 tatattgtac caaaatataa gtgaatttaa tagaatattt acttatacta tagattgatt
     1201 aataaaaaaa tggtataata acaaattgta ctttaattta ataataaggg agtggaagtc
     1261 atattgttag ggagaaatga gctatgccct tgtggaagtg gcaaaaaata caagaaatgt
     1321 tgtttaaata aagatattgt ttcagaaaga gcatgcagaa aaactgaact ttcacaaaaa
     1381 caatatacag atttatattc aaagttatat gattattcaa gacaggataa gtttaaagaa
     1441 gaatgtgaaa aagctaaaga aatgttttat ataatgcaaa atgatagtgt aaatgaaaaa
     1501 tttgaaagat tttttaatac ttatttaata caagaccaca taatggaaaa taaaaaggtt
     1561 atgacagttg gttttcttga agaaaatggt gcaaacctaa gtcaatcaga agtatcaata
     1621 ttaaaaagta tgtttgaatc atacgtaagt atttatgagg taaaagaagt ttctgctgga
     1681 aaaatagtat taaaggactg tttaagtgga aatgaacttt gtacagaaga tgtaaaactt
     1741 ctgagaagtt ttaaaatcgg aagttgtatg atagctagaa tagttgatat tgaaggaact
     1801 aacatattga tagatataac tataagtata tcaaatgagg ttaaagatat aattttaaag
     1861 gatattatga atctattcaa tcaatatcaa gatgtataca aagatatgaa gtcgttctta
     1921 atttatcata cacatatact atacaagtat atacaacagc ttttagaccc aagtatagct
     1981 gaatatttaa agagagaaag agataaaaac gatacaaaag ttaattcaga aaatgaatta
     2041 gctgaagaag aatgtaaagt tttagatact cttaaagaaa atgtagaaaa agaaaatata
     2101 gatgcatgta tagagttttg gaatgaatat aagaaaaatc atgaaaatat aaaaggagct
     2161 gaaaatggtt gggcagctgc tgttgaatac tatgttaaaa aagaagcagg acaacctata
     2221 actcaagttc aaatatcaaa gaaatacgat ataagctcta gtacactagg aaagagatac
     2281 aaggatttaa aaatatctta attaattata aaaagcttta agtcatagat aaagaatcta
     2341 tagtataata tatgtataat gtttagaaag aggtattaat aatgagtctt agtttaggaa
     2401 atgcaattgc tgtatcaacg aactttataa aatctaaccc agctgtacct gtgtacaatg
     2461 gagaagaaat atatgcagtt atttatcata tagaaatagg atataataat ggtgtatcac
     2521 ctgataccaa acaatatata ataatagact ataaagagtt tgatttatct atggataaaa
     2581 aaaatgaact aataaatatt gctaaagagt actgtaaatc taaaggtatt gtagaaaacg
     2641 aaaaccttga aataaacctt ttagacaatg aagaagcaga gaacttctta gaaaaggtgt
     2701 ttaataatat gaaggttata agaggtctta taactaaaaa aggataaata aatggactat
     2761 ataggaatag aaaatataac accttatgaa aatacatatg aatttagtgt atatgaatat
     2821 gatgatgaaa tcaccttagg tagtgaaaag ttatatgtat gtgaattaag ggttgtattg
     2881 attaaagtta attctctgta tgttgaaaga ttgcataaat cagttgaagc aatggtctta
     2941 gtaaaaaact tgaaaaaaga tttagataaa acacttgttg taaacaaaat aaagaatttt
     3001 gtgctagatg agatttgggt agaaaatcta gtaaaagaga atatagaagt tatatttgta
     3061 gaaagctagg aataacccta gcttttttat attacaatct aagagaggaa aacaatatgt
     3121 taagagtatc taatgtaaaa cttggaattg ataaagatat atctttatta aaagatgtta
     3181 tacttaagaa gctaaaaata aaagaaaaaa acttagtcaa atatagtata tataaagaat
     3241 ctatagatgc tagaaaaaaa ggaaaaatgg aatttgttta ttctgtagat gtagaagtta
     3301 aagatgaaaa taaaatactt aactcaaaaa taaaagatgt aacaaaaata aaggaaatca
     3361 gatacgtaaa tgtacctgtg ggtgataaaa aattaaagaa taatcctttg gtaattggta
     3421 gtggaccagc tggtttgttt gcaggtctgc ttttagctca aatgggttat gaaccaatca
     3481 tacttgaaag aggtcttgat gtagacagta gaaccaaaga tataagtgat ttttggacaa
     3541 ctagaaaatt aaaaaataat tcaaacgttc aatttggaga aggtggagca ggaacttttt
     3601 cggatggtaa acttacaact agaataaaag atatacgatg tagaaaagta ttagaagagt
     3661 tagttcagtt tggggcacca gatgaaatat tatactcaca taagccacat gttggaacag
     3721 atatattaaa aaatgtagtt aaaaatataa gaaatgaaat aataagttta ggtggtcaag
     3781 ttagatttaa ttcaaaagta acagatatag ttgtatcaaa tgattctata caatctgtaa
     3841 taataaatga tactgaaaaa atagatacag atacaattat attagctgtt ggacatagtg
     3901 caagagatac ttatgaaatg ttgtattcaa gaggtataaa aatagttcaa aaaccttttg
     3961 caataggagc tagagttgaa catccacaag atttaataaa taaagcacag tacaaggatt
     4021 tttataatca ccctaggtta ggagctgcag attatagact tatagagcat gtttcaaatg
     4081 gaagaacagc atatactttt tgtatgtgtc caggaggtag tgtcatagca tctgcatcaa
     4141 atgattttga aatagttaca aatggtatga gtgaacatgc aagagataaa ataaatgcaa
     4201 atagtgcatt tttagtaaat gtaacgccag aagattttaa gagtgataat ccactagcag
     4261 gtgttcattt ccagcagaag tatgaaaaat tagcttttga attaggtgga aaaaattata
     4321 atgcaccagt tcagcttgtt ggagatttta taaacaataa gacttctttg aatttaggaa
     4381 gtgttgagcc atcatataga ccaggatata cacttacaaa tttaagtgaa tgtttgccta
     4441 gcttcgtaac agagactatg agagaagcgt ttatatctct tgataaaaaa ttgaatgggt
     4501 ttgcaatgta tgatgctgtt ttgacgggag tagaaactag gtcatcatca ccaataagaa
     4561 tagtgagaga tgaaaatact ttagaatcag tgagtattaa gaatctatat ccatgtggtg
     4621 aaggtgctgg atatgcaggt ggtatagtta cagcagcagt tgatggtata aaatgtgcag
     4681 aaaaaataat acaaaaatac accaataata caaaaattta acataaactt aatgattttt
     4741 taatatttaa catgaattta acattatcac tcctataatt tgataaaata caataggtta
     4801 taaaattttt agatacagta atctctttac aaggaggaaa taatttgaac attataataa
     4861 gtctaatggg tggattaggt ctgttcttat atggtatgaa ccttatggga gaaggtcttc
     4921 aaaaatctgc tgggacaaag ctaaaaaaga taataaaact acttactagt aacctattta
     4981 tgggagtttt ggtaggtaca ggagttacag cagtaataca aagttcaagt gctactactg
     5041 taatggttgt tggtttcgta aatgcaggaa taatgacttt aaaacaggca ataggagtta
     5101 taatgggtgc taatataggg actactgtta cagcccaatt ggtatctttc gacttaactg
     5161 gtatggcccc agtagcatta ggtgtaggta ttatacttta tttatttgga aataagccta
     5221 gaataaaaaa tatagccgaa atacttatag gttttggtat attatttaca ggtatggatt
     5281 ttatgaagat ggcagtggag ccactaagag actatcaagg atttactgac ttacttgtta
     5341 catttggtag atatccacta cttggattat tattgggatt tgggattaca gcaataatac
     5401 aaagttcaag tgcatctatg ggtatgttgg ttgcactggc agcagaaggt ctagtgccac
     5461 tatcagcagc actgccaatt ctttatggcc aaaatattgg tacatgtgta acttcactgt
     5521 tatcaagtat tggtgctaac aaaaatgcac gaagagcagc tatgatgcat ctaatcttca
     5581 atgttttagg aacggtgata ttcttaatat tcttgaataa accagtagta agcatggtta
     5641 caagttggga tccaagcaat gttgcaagac aaatagccaa tacacataca ttgtttaata
     5701 taatatctgt attgatactt ttaccattta caagtcttat tataaaacta gctataaagc
     5761 ttgttcctga tagagcaggt gatatagatg aagatgaaac taaaactatt aaatatatag
     5821 atgatagaat gatagaaact ccttctatag ctcttgcaaa tacgataaaa gaagcacttc
     5881 gtatgggtga gaaggcgaag gaaagcctaa atgcatctat ggaagcttta gtagaacatt
     5941 caactgaaaa aatagataag acatatagac gagagagatt aatcaatgat ttacagaaag
     6001 ctattttaaa ttatttactt aaactttcaa aagcagcttt agatgatgat tcaagagaag
     6061 ttgtggatac tttgtttaat acagtcaatg atatagaaag aattggtgac cacgctaaaa
     6121 atatagctga attatcacaa gttgcaatag attcaaatat ttatttctca gaagaaggac
     6181 aatctgaact tgatgttatg tataatagag ttgtttcagc atatacttat gcattagaat
     6241 caatgaggag cgataatgtt gatttagctt gcaaggttat aaaaattgaa gaacaagttg
     6301 atataatgga gaaatcttgt agagctaatc acatgtatag attgaataat aatctatgta
     6361 gtatagaaaa tggagttatt tatttagatg taataagtaa tttagagaga atatctgacc
     6421 atgctgtcaa tatagcacaa caagttatag cgaagagatt aggaaatgat taaaaataat
     6481 taatttaaaa taatataaaa tttaaaatag aggataaata aaagagaaac tttaaatgat
     6541 acgtttagag tttctttttt tgtaaattta tttgactaaa atttttaaat ttatacatag
     6601 ttatagtatt tagaagaatc gatttcctga taataaatga tgagatatgt atgattttgt
     6661 ggcaaacttt taaaaaaaac acctatattt tgtgttataa tctctttaaa acgaatatgc
     6721 tgaaaagagg gatttaaatg ggaaaaataa attttgatta tagtaaagct acagagtttt
     6781 tttgtcaaaa cgaaatagat gtcatgcaac catatgtaga tgttgcgcac gacatgttac
     6841 ataataaaac tggtttagga aatacttttt taggatggat agaccttcct aaaaattatg
     6901 ataaagaaga gtttgacaga ataaaaaaat ctgctgataa gataaaatca gactcagatg
     6961 ttcttttggt aataggtata ggaggctctt atttaggttc gagagctgct atagatatgg
     7021 taagtcattc ttttaggaat ggacttaaaa aagagcaaag aaaggctcca gaagtatatt
     7081 ttgtagggca taatataagc tcaacatata ttatggattt attagatata attgaaggaa
     7141 aggatatttc tgtaaatgta atatctaaat caggaactac tacagaacca gctctggctt
     7201 ttagaatatt taaagattac ttagagaaaa agtatggtaa ggaagaagca agaaagagaa
     7261 tttatgcaac aacagatgca agtaaaggtg cacttagaca gttagctaca gaagaaggat
     7321 atgagacttt tgtaatacca gatgatgtag gtggtcgttt ttctgtattg acagcagttg
     7381 gattacttcc tattgctgct gctggacttg atattgatgc tatgatgaaa ggcgcaaatg
     7441 atgctagaga agcatttcaa aatcctgact taaaaagtaa tgatagttat agatatgctg
     7501 ttgctagaac aattttacat agaaaaggaa aagatgtaga gttattagtg aactatgaac
     7561 ctcaactaca ttatgtaagt gagtggtgga aacagcttta tggagaaagt gaaggaaaag
     7621 aaaataaagg tttattccct gcttctgtag atttctcaac agatttacat tctatgggtc
     7681 aatacataca agatggaaaa aggcttttat ttgagacagt acttaatgtt gaaaactgta
     7741 agagaaatat aactataagt tcagaggaag tagacttaga tggtttaaat tatttagcag
     7801 gtaagactgt agattttgta aatcataaag cttttgaagg aactctattg gctcatacag
     7861 atggaaaagt acctaattta gtaataaata tacctcaact agatgagtat aattttggat
     7921 atttagttta tttctttgag aaggcttgtg gaataagtgg atatttattg ggagttaatc
     7981 catttgacca accaggagta gaagcttaca agaaaaatat gtttgcttta ctaggcaaac
     8041 caggttatga aaaagaaaag gaagagctag aaaaaagact taaataattt taaatagtta
     8101 aggtttaatt aagattaaaa taatataatg aaatcatcaa aaaggagttt actcaaaata
     8161 gatgatttca ttttttttat gaaaaattgg gaaaaatata ttttgataat ttatattata
     8221 ttaagatagg gagtggtatg agatgtcaag aagaaagaaa gggataagtt tagtaatatt
     8281 agttgctata ataagttcaa tacttagtag ttttctaaca ataattttag ttaaggacaa
     8341 tttagtaagc aaatctacag gaagttctac gccgatagtt gtaaatgatg atggtaagag
     8401 tcaaaatatt tatcaagcag ttgcagaaaa agctacgcca tctgttgtag gtattacaac
     8461 aactagtgtt gatactagta atatgtttgc aataccaact gaaacacaag gtgtaggaac
     8521 tggaatcata gttgattcaa atggatatat acttactaat tctcatgtta tatcagatgg
     8581 tcaagctaca agtgtaaatg tattattcaa tgatggttca acaacttcag gtaaagtagt
     8641 atggtttgac caacaacttg atttagctat agttaaggtt gataaaactg gactaacacc
     8701 agcagaattt gctgatagtg acaaagtaaa agttggagat atatcaatag caataggtaa
     8761 tcctcttgga ttagattttc aaaaaacagt tactcaaggg ataataagtg gattagatag
     8821 aactatacaa acagaaaaaa ctaatatgac tggtttatta caaactgatg caagtataaa
     8881 tgcaggaaat agtggaggac cattgttaaa tcaaaaaggt caagtaattg gtataaacac
     8941 agcaaaagct tctcaagcag aaggattagg atttgcaata ccaatcaata cagctaagag
     9001 tatagttgaa gaagtaatca aaaatggaaa atatgaaaaa gtaactttag gcataaaagg
     9061 tacagatgta tcaaattatg aagcagcaac aggtacaaaa ttaagtactg ataaaggtgt
     9121 ttatgttgca gaagtaatat ctggttcatc agcagaaaaa gctggagtaa aggtagggga
     9181 tattataact aaagtaggag atacagatat aacaggtatg aatgatttaa ataaaaagtt
     9241 gtatactttc tcaaaaggtg ctagtacaaa aataacagta aatagaggcg gaaaagcagt
     9301 aacaataaat gtgaatttct aaatatgacc aaaaagatag agactacatg gtaaagtgta
     9361 gtctctattt ttatttaatt tttatagtat atacatctaa attaattaaa atgatgtatt
     9421 gtttatagtt tattgctata ttttcttata aaaataaatt taataaatat ttaaatttaa
     9481 tttacaaaaa caatataaat atcataataa aataaaattt tttaatatta ctaaaaatat
     9541 atagacaaaa taataacaaa tatagtatta tgtaattgta gaaatgcttt tcataggtat
     9601 attctatgaa gatgaattgc ataaaaatga aaaaatggaa tggatattat ttaggggtga
     9661 aaaatcatga atccattagt tataaactta caaaaatgta gcatacatga tggaccaggg
     9721 ataagaagta cagtattttt taaagggtgt ccacttgaat gtgtttggtg tcataatcca
     9781 gagagtcaaa catatacaaa acaagttttg tataatgaag aaagatgttc aaaatgtgaa
     9841 gcatgtataa atatatgccc tcataaggca atttacaaag gtgaaacaaa aatatgctta
     9901 gaccaagata agtgtgagtt ttgtgaaact tgcttagact attgtgtaaa caatgcaaga
     9961 gagattgttg gtcaagagta ttctgtaaga gatttggtta aagagataga gaaggataga
    10021 attttctatg aagaatcagg tggtggagta actctatcag gtggagaagt aatggctcaa
    10081 gatatggact tcatttgtgg agtaataaac atgtgcaaat caaagggaat ccatgtagca
    10141 attgatacat gtggctatgc aaagtcagaa aattatgaaa gagttgctaa atgtgcagat
    10201 ttgtttttat atgatattaa gcttattgat gaagataagc acataaaatt tacaggaaaa
    10261 tcaaatgact taatactgaa aaatgttaag attttaagtg aattaggggc taacataaat
    10321 ataagaatac cattaattgt aggagtaaat gtagatgatg aaaatttaga ggttaaaaaa
    10381 atgatagagt ttttaaagcc tttgaatata caagcagtaa gtcttcttcc atatcataat
    10441 attggtaaac acaagtatga taaaatttat aaaaagtatg aaggagaaga actacaaaga
    10501 ccatcagaag aaaaattaga ggaaataaaa agactgtttg aagcaagtaa tttcaatact
    10561 aagattggag ggtaataaaa tggcaagagg aacttttgag agaactaaaa aattaagaga
    10621 agaaagtatt aatgcagaac cacacatatc tattgaaaga gcagtactta tgacagaagc
    10681 ttataaaaaa tatgagggaa gtgtagagat tcctgtactt cgtgctttat catttaagca
    10741 ttatattgag aatagaactc ttagcataaa tgatggagaa ttaatagtag gtgaaaaagg
    10801 tgattctcct aatggagcac caacatatcc agaaatttgt tgtcatacaa tggaagattt
    10861 agaagtaatg cacaatagag atataataaa ttttagcgta tcagaagaag ctagaaaaat
    10921 acataaagaa gaaataattc ctttttggaa aaagagacaa acaagagata agataataaa
    10981 tgcaatgaca cctgagtggt tagcagcata tgaagcaggt atgtttacag agtttatgga
    11041 acaaagagcc ccaggacata cagtttgtgg agatacaata tataaaaaag gatttttaga
    11101 tttaaagaaa gacatagaag caagattaaa agagctagat tttcttaatg atttagatgc
    11161 atataataaa aaagcagatt tagaagctat ggcaatagct tgtgatgcaa tggttatatt
    11221 aggtaaaaga tatgctgaga aagcaagaca aatggcagaa gaagaaacag atgaagctaa
    11281 gaaacaagat ttattactaa ttgctgaaac ttgtgatgtt gtaccagctc acaaaccaga
    11341 aacttatcat caagctatac aaatgtattg gtttgttcat ataggggtta ctactgaact
    11401 taatatatgg gatgctttta ctccaggaag acttgaccaa catctaaatc ctttctatga
    11461 aagagatgta gaaaatggaa tactagatag agatagagca caagaattac ttgaatgttt
    11521 atgggttaaa tttaacaatc agccagcacc accaaaagtt ggtataacat taaaagaaag
    11581 tagcacatat acagattttg caaatataaa cactggtgga ataaatccag atggtcaaga
    11641 tggtgttaat gaagttagtt atataatact tgatgttatg gatgaaatga aattgataca
    11701 acctagttca aatgttcaaa taagtaaaaa gactcctcaa aaattcttaa agagagcttg
    11761 tgaaatatca agaaaaggat ggggtcaacc agcattttat aatactgaag caatagttca
    11821 agagcttatg gaagctggaa aaactataga agatgcaaga cttggtggaa ccagtggttg
    11881 tgttgaaact ggatgttttg gtaaagaagc atatgttcta actggatata tgaacattcc
    11941 aaaaatactt gaattaacat taaataatgg atatgaccca attagtaaaa aacaaatagg
    12001 tattgaaact ggagacccta gaaatttcca atcttatgag gaactatttg aagcatttaa
    12061 aaagcaatta cattatatga ttgacataaa aatagaagga aatgctgtga tagaaaatat
    12121 atgtgcaaaa cacatgcctt gtccacttat gtctacaata gttgatgatt gtatagaaaa
    12181 aggcaaggat taccaaagag gtggagcaag atacaacact agatatatac aaggtgttgg
    12241 tataggaact ataacagata gtttaacagc aataaaatat aatgtatttg ataagaaaaa
    12301 attcgatatg gatacattgc ttaaagcact tgatgctaat tttgaaggat atgaagctat
    12361 acttaattta gtttcaaata agactcctaa atatggaaat gatgatgatt atgctgatga
    12421 aataatgcaa gagatattca atgcatatta caatgaggta actggtagac caactgtttg
    12481 tggtggagaa tacagagtag atatgttacc aacaacttgt catatatact ttggagaaat
    12541 tatgggagca agtccaaatg gtagactttg tgcaaaacca gtttcagagg gaatttcacc
    12601 tgaaaaaggt ggagatacta atggacctac agcagttata aaatcttgtg ctaagatgga
    12661 ccacataaaa actggtggaa cattattaaa tcaaagattt gcaccatcag tagttcaagg
    12721 agaaaaaggg ttagataata tggctaatct agtaagagca tactttaata tggatggtca
    12781 tcatatacaa tttaatgtat ttgataaaaa tgtactgtta gaggctcaaa agaatcctca
    12841 ggattataaa gacttaatag ttagagttgc aggatatagt gaccatttca ataatttaag
    12901 tagaacacta caagatgaga taataggaag aactgagcaa acattctagg tttgcttgta
    12961 aataaaactt cttactatat aaaatcgtaa ctgatataat aaagtataaa tggtttgatt
    13021 ccatttttaa aattttagat taattatgag ctaactttct aaataggaag ttagctcgtt
    13081 aagtttaatg aaaaaatcgt taaatttata tttagtaaat catacacata ttagtaagta
    13141 atacatacaa aagaataatt tattatagtt ataataaggt tatattttat aaaaataaga
    13201 taattttaag cagttaaaat aaagtcaatt tagctacttt aaaataaaac taatagaaaa
    13261 aaggagattt gatatgaaaa ctttaggatt tattggttca gggaatatgg gaagtgcaat
    13321 gataggtggc atagtacagt caggattagt aaaggcagaa gatataactg tatcagattt
    13381 aagccaagtt gccttagata aagtaaaaga agaatttgga gtaaatacta caactgattc
    13441 aaaggtagct gttacaaatt ctgatgtggt aatagtagca cttaaaccta atatatgcga
    13501 aaaggcttta actccactta aagaattaat agatgcaaat aaaataatag tatctatagc
    13561 agcaggtaaa actatagaaa gtctggaaag ttttataggt tcagataaaa aaatagtaag
    13621 agtaatgcct aatactccag cccttgttgg cgaaggaatg tcagctcttt gtaaaaatag
    13681 taatgtaaca gatgaagagt taaatatgat taaggctctg tttgaatctt ttggtgaggc
    13741 agaaatagta tcagaatatt taatggatac agttacaggt attagtggtt cttctcctgc
    13801 atatgtattt atgtttatag aagctatggc agatgcagca gtattagctg gaatgccaag
    13861 acaacaagct tataaatttg catctcaagc agtaatgggg tcagctaaga tggttcttga
    13921 aactggaaaa catccaggtg aattaaaaga tatggtttgt tctccagcag gaactactat
    13981 agaagctgtt aaggtattag aagaagaagg ctttagagca gcagttataa aatctattgt
    14041 tgcttgtata gataagtcta aagatatgag taaataacag atgtaattaa gtttactata
    14101 tggtttcttg aattgttttt ttagtgctta tttatatcta tacataaatg tatttggtat
    14161 aagtaaaata agagtaattt actataaaaa ggaatttaat gattgagtga gaatttatta
    14221 cttaaatatt aataattaaa tagatatatt tttaactata tttgagatat atcattgtga
    14281 aaaaataaaa tttataagta ttattgtgag gttataagta gatttattta aaaataaatt
    14341 tatttatagc ctt
//
LOCUS       DAJMZY010000104        14231 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.105, whole genome shotgun sequence.
ACCESSION   DAJMZY010000104 DAJMZY010000000
VERSION     DAJMZY010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 14231)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14231)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14231
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.105"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     regulatory      complement(123..206)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
     gene            complement(439..1281)
                     /locus_tag="OE968_003022"
     CDS             complement(439..1281)
                     /locus_tag="OE968_003022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein"
                     /protein_id="HCP7220282.1"
                     /translation="MFKKKIGVLLASTMLVGALAVGCSSNSGGSGDSGDSSKVSVSGS
                     TSIGPLMETIGEKFQEKNQGVSVEVQQIGSSGGIKNAIEGTSEIGMSSRDLKDEEKSA
                     GLKETKIAIDGIALITNTANSVKNLTMDQVKGIYTGKITNWKEVGGNDAPIVIVSREE
                     GSGTRDGFQEIVGFDSEELTKDAQISDGSGNIKTTVEGNENAIGYISFGYVDEKVNSL
                     KINDVEATDANVIANKYPISRPFILVNKEDGLSEKGKALIDYILSDEGQALVSEKGFI
                     KVNQ"
     gene            complement(1533..3317)
                     /gene="pepF"
                     /locus_tag="OE968_003023"
     CDS             complement(1533..3317)
                     /gene="pepF"
                     /locus_tag="OE968_003023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HCP7220283.1"
                     /translation="MGTDRSTIEEKYKWKIDKMYSSKEEIEKDISKVKNLIQEVKEYK
                     GKLSESKENLYKVLNISENASRIVQNLYVYTHMKQHEDTRINDNQGRATKTEMLSTDL
                     GVATSYIVPEILAIEENKLSEYLKDEKLSFYTKYIKDILRDKPHTLSEREEEILAATS
                     ELSTIPENVYDMLAYADMEFPEIEDEEGNKVKLSHSNYSLFIKSKNSRVRKDAFEGEF
                     STYEKYKNTFASTLYGGIKSEIFYAKTRKYNSAIEASLFSDDVSLDVYNNLISAIDKS
                     IPNLNKYVELKKKFLGLNEIHMYDLYVPLTDKFDMDIPYDKAQDIILEALKPLGEEYL
                     KVIKSAFDEGWIDVYDNEGKKGGAYSWGSYDSHPYILMSYKNDLNSLFTLVHELGHSV
                     HSHYSRTSQPFLYSDYKIFVAEVASTLNELLLINYLLENSKSKDETIYLLNYYLEQFR
                     TTVHRQTMFAEFEKIVHQRVESGEPLTADEFTNIYYKLNEKYYGKSAIVDKQIGIEWA
                     RIPHFYSNFYVYKYATGFSAASALSQQILSEGSTAVDRYINFLKSGGSEYPLEQLKSA
                     GVDMTKKESIEEALNVFAELVNKLEKEL"
     gene            complement(3383..4048)
                     /locus_tag="OE968_003024"
     CDS             complement(3383..4048)
                     /locus_tag="OE968_003024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HCP7220284.1"
                     /translation="MIDIGSKEIAIRLLLALIIGGIIGLEREKIRQFAGFRTHILIAI
                     GSCIVSITSIQLFFDYNLYTNADPARMPAQVLSGIGFLGAGAILKNKGGVKGLTTAAG
                     MWATACIGIAVGYGYYELAILGGLFVMIALFVLRIINTFLFSQEKNVLILKLSNLDSI
                     PFLYDKFEKNQLIVRNMEIECRNEEYWKVNFFVSYAKRIHLHDVMKEINMIEGVINVD
                     YLD"
     gene            complement(4199..4360)
                     /locus_tag="OE968_003025"
     CDS             complement(4199..4360)
                     /locus_tag="OE968_003025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartyl-phosphate phosphatase Spo0E family
                     protein"
                     /protein_id="HCP7220285.1"
                     /translation="MANNELEALKNEIEAVREEINTYIEYPEIFQEELVESSKKIDIL
                     INKYMYLSK"
     gene            complement(4438..4947)
                     /locus_tag="OE968_003026"
     CDS             complement(4438..4947)
                     /locus_tag="OE968_003026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HCP7220286.1"
                     /translation="MKTRKMTFLGLMIGYSLALYVLETYIPNPLIVIFPGAKLGLSNI
                     ITLISLMLLGVKDTVIIVTIRVILSSIFAGPLSYLLFSIGGAYLSLLFMYLASKIKDL
                     SLIGISIIGAIGHNIGQLIVASLIIENILAIGYLPFMLMASLVTGMFVGLVSRYTIPK
                     LKHFYSKFY"
     gene            5153..5371
                     /locus_tag="OE968_003027"
     CDS             5153..5371
                     /locus_tag="OE968_003027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HCP7220287.1"
                     /translation="MTVYDLKIGEKGFINSIDGDIKLSKRLLALGCINSTEIEVKKVA
                     PLGDPIIIRFRGFDLAIRKSDAKNISLQ"
     gene            5389..7335
                     /gene="feoB"
                     /locus_tag="OE968_003028"
     CDS             5389..7335
                     /gene="feoB"
                     /locus_tag="OE968_003028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HCP7220288.1"
                     /translation="MINVALLGNPNVGKTTVFNLLTGSNQYVGNWPGVTIEKKEGFLG
                     KEIKVVDLPGIYAMDTFSNEEKVSKSYLENEDVDVIVNVVDASNLSRNLYLTTQLMQF
                     NKPIVILLNMLDIAESKGVNIDAKKLSEELGVIVVPIIAKKKNGVDRIEEEIKGATQK
                     AFIYQKNFGSETETYKKLESILSRCTKTTYTQKKSISDKIDNIVLNPILAYPIFIGVL
                     FLLFKFTFDWVGGPLQEGFASLIEAYISAPVSDMLSNSSPWFKSLIVDGIIGGVGGTL
                     PFFPLIFTLFFGISLFEDSGYMSRTAFLMDKVMRKVGLSGKAFIPIVMGMGCSSPAIM
                     ATRTLESEKDRRVTALIAPLMTCGAKLPIYALFVAIFFPHNAALVTTSLYLVGIVMAI
                     VVALFLNKTAFKTEAEPFILELPEYRIPTIDALIKNTWNKSKGFLIRVVTVMFAMSVV
                     IWGLSSFNVFGYTEDINVSFLATLGHIISPIFKPLGFDDWRTSVAILSGLGAKEIVVN
                     SLNILYGNLTVVLPTIFNGVTAYTFLIFTALYTPCIAALATMKKEYGNKMMFTSFAYQ
                     FILAWIMAFIVKSIGGVLFMGNSIMEALIGGIIIVLALFILFNKFKSTKNGNVCSGCS
                     ICSGCPSANSCSSKEDSNKKNNAH"
     gene            complement(7514..8569)
                     /locus_tag="OE968_003029"
     CDS             complement(7514..8569)
                     /locus_tag="OE968_003029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HCP7220289.1"
                     /translation="MTIQDYMLETPVRMREIISNADSLFNEVKRTNLKKIIITGSGTS
                     YHSGVQVQPYLQNLLDIDVVKMYPFMITEDTFKFDNENTLVVGVSQGGSSYSTYNAMK
                     LAEDKGCKIASMAGCKNALIDEISDYILTVNCGEEKSGAKTKGYYCTKLNLMLLGLQI
                     AREKGIISSEKYNEEINKILDAINRFEAVYKLSKQWIERNKEKLVNSKEIRIIGHSDI
                     YGDTLEAALKLLETMRIPVTGYEFEEFIHGIYNAINSDSTIFILDTGKEPRVTKMIDV
                     LSGWTENVFAIGRDVTENDKNLKIDITDNPYYQTFNFIVPIQLICGEIPTLRGVDPSV
                     PKDTRFHMKLGSKKLNK"
     gene            complement(8617..9417)
                     /locus_tag="OE968_003030"
     CDS             complement(8617..9417)
                     /locus_tag="OE968_003030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HCP7220290.1"
                     /translation="MNKLTKKELRSMFWRSFALQGAFNYERMQNLGYCYSMLPAIKKL
                     YNKKENQAKAIERHLEIFNTTTVVVPAILGITAAMEEENANNPEFDESSISAVKTALM
                     GPLAGIGDSLFWGTFRIIAAGVGVSLAKEGNIFGPLLFLLLYNIPAFALRIFGLKYGY
                     QVGVNSLERIQREGLMEKIMSMATTVGLFVVGGMVATMLSITTPLKFNLNGAEVILQD
                     ILDKIIPNMLPLTFAFVIYYMLKRKVSVTKLTIGTIVTGIALHAIGLL"
     gene            complement(9410..10201)
                     /locus_tag="OE968_003031"
     CDS             complement(9410..10201)
                     /locus_tag="OE968_003031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCP7220291.1"
                     /translation="MLVQATMLAIIAGVGILDGRIFGQSMLDRPIVTGMLVGLVLGDI
                     KSGIMIGAQLELIWMGIAGIGAATPPDVVTGGVLGTAFAILSGNGAEVALAVAVPVAV
                     LAQSLGVLVRIINSYFSQKAVFYAKQADFKKVTIMMWLPVILFFLSTSVPTFLAIMIG
                     ADKVTALINAIPKVILDGLGVAGTLLPAVGFALLMDMLLSKKMSVFFFIGFLLASYGG
                     LDITAIALFGVCVAFVLNFYINNKENNQNPQLAINTLTEGEIDFE"
     gene            complement(10241..10663)
                     /locus_tag="OE968_003032"
     CDS             complement(10241..10663)
                     /locus_tag="OE968_003032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HCP7220292.1"
                     /translation="MKKFLIATHGELSRELVDTSKLIIGSLTNIEYFCMTTDKSADDA
                     EKEIRSILSNNKDSEEFVVLTDVFGGSVANICTNLLLQGFKFELLTGVNLPMLLSILL
                     LVEEDTKLIVKSGLEEAKNGIVYVNELLENQNKIKNVM"
     gene            complement(10679..11158)
                     /locus_tag="OE968_003033"
     CDS             complement(10679..11158)
                     /locus_tag="OE968_003033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCP7220293.1"
                     /translation="MVSLMRIDDRLIHGQVAYGWATSLGINVILVANDEAKNDQMKAM
                     SLNLAKPSNVTLYIRGVEESGEIVEKFASSKKSNVLVLVKNTKDALVVAKNSGGVLKE
                     INVGGLRYEEGKKKLTDLVAVDDDDINNFKQIGDLGIDIEFRMLPRDKKKQLSDLIK"
     gene            complement(11290..14046)
                     /locus_tag="OE968_003034"
     CDS             complement(11290..14046)
                     /locus_tag="OE968_003034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HCP7220294.1"
                     /translation="MRDEILSFVNECVLFNSFDELKKESGIITEDIVKKFNLSRTQSS
                     RLLNDLVKSDNLIKINSRPVIFLPKNKINDVVGPTKKSIYENLDELKNECKLLKQETV
                     FNSIIGYDNSLKEVIEQIKTAVLYPNGGLTIMLTGESGVGKTFLAKIIYKYSVSSNVL
                     EKNSPYNVLNCAQYYNNLELLSSLLFGHVKGAYTGANESRAGLIEQSDGGVLFLDEVH
                     RLNSEGQEKLFTFMDTGTFSRIGENGVIRKARVRLIFATTESLSEFLQTFLRRIPINI
                     YVPNIEERGTIEKRKIVEHFIYEESKVLGLPIEITQITLNAILKIKFKGNIGECKNVI
                     KYACGRAYAKNQRRNGNIFVTLQDLPRNLYIENVDIFQFQSGKSKSIIFSPKQFSIEM
                     SNGRNKRNIIYQSFIKCLDYFDRLEKNEITKEKFSKKSSNLMIRLMDNLVFSNNDENN
                     NVLMELIISIMQDIFRNLEVNNNIKYDGNNVLAFSSYLYLKDESYQLSDEYKALENKL
                     LIYLKKESYKEYSIISKISTLITNRLDMYLNNVDTIIMIIFIKSTIIRMKFNQVNATI
                     IAHGYATASSMANVCNRMLGKNIFTAIDMPIDATIADVSKQMSRYLEGDRIKNGLIVL
                     FDMGSLNLIYEDLKNKINSPMLFIDQISTISALEVGNLLMQGKNIEEIAEIMDEETKP
                     NIQLYYPQKNKEYAIISSCFTGIGIAIKIQHLLSESLIGIVDVKIIPYDYDSLVSMGD
                     KEPVFEMYDVMAIVGTANPNVNGVDFILLEDIISGKGEDDVFRIFSRVVENEKIKNIN
                     DSIVKNFSLIRVIDSLTILDSKKIIERIEEGINAIENIQKKKLSNDKKISLYVHLSCM
                     IERLVRQTEIEEYTDMDLLIKNHHSEVKLIKNAFSVLEKSYSVQIPISEIGYIYNIIY
                     GLPQ"
BASE COUNT         4611 a         2470 c         1616 g         5534 t
ORIGIN      
        1 gctactttaa aagccaaaat tttacctatc aataaaaatc ttaacgacta atactcttat
       61 tttcaaattt tgcaacattt ttgttaattt taaaacaaaa aaagactatg caatataaaa
      121 attatattca tagccggttg caccactaac tccatatatc tctagatgcc caataataag
      181 atatacttct cagtttctaa aatattttta ttaaaaatct tttatatatt ttcataaatt
      241 tcttttttat tctaacattg taatattatt ttgtcaatat ttccatattc ttagagataa
      301 gatactaaaa tacctatttt atctaaagat atttatattt ctacattcaa taatagacaa
      361 taccctgcaa gttaaagcat catttttatg agcttatctc acagggtatt atatgtttac
      421 tttatattat aactcttgtt attgattaac tttaataaat cctttttctg aaacaagtgc
      481 ttgtccttca tcacttaata tataatctat taaagcttta cctttttctg acaaaccatc
      541 ttctttatta actaatataa atggtcttga tattggatat ttattagcta ttacatttgc
      601 atcagttgct tcaacatcat ttatttttaa actatttact ttctcatcaa catatccaaa
      661 tgatatatat cctatagcat tttcatttcc ttcaactgta gtttttatat ttcctgaacc
      721 atcacttatt tgtgcatctt tagttagttc ttctgaatca aaccctacaa tttcttggaa
      781 tccatctcta gttcctgaac cttcttctct tgatactatt actattggtg catcatttcc
      841 tcctacttct ttccagttag taatctttcc tgtatatata cctttaactt ggtccattgt
      901 cagatttttt actgagtttg cagtattagt tatcaatgct ataccatcta ttgctatttt
      961 agtttccttt aatccagcac ttttttcttc atcttttaaa tctcttgaac tcattcctat
     1021 ttcagatgtt ccttctatag cattttttat acctccagaa gaaccaatct gttgtacttc
     1081 tacactaaca ccttgatttt tttcttgaaa cttttctccg atagtttcca taagaggacc
     1141 tattgaagtt gaacctgaaa cagaaacttt gcttgaatct cctgaatcac ctgaacctcc
     1201 tgagttagaa ctacatccta ctgctaaagc tccaactaac attgtactag ctaaaagaac
     1261 gcctattttc tttttaaaca ttttacttac ccccgcttat attttaattt tttgttgtca
     1321 tttttctata ttttaataat acagattctt tgttaaatga atattagagc agggttaagt
     1381 aaatgtaaat attgttaaat acatgtaaaa acttaatttt atatgattta ttcttaatta
     1441 gattaacttt ttaaagttac tttaggcaga tataaacata atacaactca tattatcaga
     1501 agtcttcatt gaagctatca acctatcaca tcctataatt ctttttctag tttattaact
     1561 aattcagcaa atacatttaa ggcttcctct atagattctt ttttcgtcat atctacacca
     1621 gcagatttta attgttctag tgggtattct gaccctccac tttttaagaa gtttatatat
     1681 ctatctactg cagtacttcc ttctgaaagt atctgttgac ttaaagcact tgcagcagaa
     1741 aaccctgtgg catacttata tacatagaag tttgaataaa aatgaggtat tctcgcccat
     1801 tctattccta tttgtttatc tactattgca gattttccgt aatacttttc atttaatttg
     1861 tagtatatat tagtaaattc atcagcagta agtggttctc cactctctac cctttgatgt
     1921 acaatttttt caaattcagc aaacatagtt tgtctatgaa ctgtagttct aaattgttct
     1981 aaataataat ttaataagta tatagtttca tccttagact tagaattttc taataaataa
     2041 tttataagaa gtaattcatt taatgtagat gcaacttctg caacgaatat cttatagtcc
     2101 gaatataaaa atggttgact tgttcttgaa taatgactgt gaacagagtg ccctaattca
     2161 tgaactaaag tgaatagaga attaaggtca tttttatagc tcattaatat ataaggatgt
     2221 gaatcataac ttccccaaga ataagctcct ccttttttac cttcattatc atatacatca
     2281 atccaccctt catcaaaagc actttttatg accttcaagt attcttctcc taaaggttta
     2341 agtgcctcta atatgatatc ctgtgcttta tcatatggta tatccatgtc aaatttatct
     2401 gtcaaaggaa catacaaatc atacatgtgt atttcattca atcctaaaaa tttcttttta
     2461 agctcaacat atttatttag attaggaata cttttatcta tagctgatat aagattattg
     2521 taaacatcta aacttacatc atctgaaaat aaagacgctt ctattgctga attatacttt
     2581 ctagtttttg cgtaaaatat ctctgatttt attccaccat aaagcgttga ggcaaatgta
     2641 tttttatatt tctcatatgt tgaaaattca ccttcaaaag cgtcttttct aactctacta
     2701 ttcttacttt ttataaataa agagtagttt gaatgagaaa gcttaacctt attcccctcc
     2761 tcatcttcta tctcaggaaa ttccatatct gcatatgcta acatatcgta tacattttct
     2821 ggaattgtcg ataattctga tgtagctgca agtatttctt cctctcgttc actcaaagta
     2881 tgtggtttat ctctcaatat atcctttata tattttgtat aaaaggatag cttctcatct
     2941 tttaagtatt cacttaactt attctcttct atcgccagta tttctggaac tatataagaa
     3001 gtagccacac ctaaatcagt agataacatt tctgtcttag tggctcttcc ttgattatca
     3061 ttaattctag tatcttcatg ttgtttcata tgagtatata catataaatt ttgaacaatc
     3121 ctagatgcat tttcagagat atttaatact ttatataagt tctccttact ctcagaaagc
     3181 ttccctttat attcttttac ttcttggata agatttttta ctttacttat gtctttttca
     3241 atttcctctt tactggagta catcttatct atcttccatt tgtacttttc ttctattgta
     3301 cttctatcag ttcccatatc atacacctct attttaattt gttttatatt ttattcactt
     3361 tacaaaatat attgtatata ttttagtcca aataatctac atttattact ccttctatca
     3421 tatttatttc tttcataaca tcgtgtaagt gtattctctt agcataagat acaaaaaaat
     3481 taaccttcca gtattcttca ttacgacatt ctatttccat atttcttacg ataagttgat
     3541 ttttttcaaa tttatcatat aaaaaaggta tagagtccaa attgcttaat tttaatatca
     3601 atacattctt ttcttggcta aataaaaacg tattgattat cctaagcaca aataatgcta
     3661 tcattacaaa taatccacct agaattgcca attcataata accatatcca actgctatac
     3721 caatacatgc agttgcccac atcccagcag ctgtagtaag cccttttacc ccacctttat
     3781 tttttaaaat tgctcctgca cctaaaaaac caattccaga taatacttga gcaggcattc
     3841 ttgctgggtc agcatttgta tacaaattat aatcaaagaa taattgaatc gaagttattg
     3901 aaacaataca agaacctatt gcaattagta tatgtgtcct aaatcctgca aactgtctta
     3961 ttttttctct ctctaagcct attattcctc ctattattag tgctaatagt aaccttattg
     4021 ctatctcctt acttcctata tcaatcataa tataaaaccc tcctgactta attacaactt
     4081 atgtcctaca gataatttac acatcagaaa tactatttta tatcttaata ttattattaa
     4141 tatatgtaaa atatagccat ctgttaattt ttgatacaaa aaaacccaca actgtgggct
     4201 atttgcttag gtacatgtat ttatttatta atatatctat tttcttactt gattctacta
     4261 actcttcttg aaatatttct ggatattcta tgtatgtatt tatctcttcc ctaactgctt
     4321 caatctcatt ttttaacgct tctaattcat tgttcgccat aataatcacc actattacaa
     4381 atttgtatat ttttatatac attttatcaa acaatattat attttgtcaa tattatgtca
     4441 ataaaactta ctataaaaat gctttaattt aggtattgta tacctggata ctaagcctac
     4501 aaacatacca gttactaatg atgccattaa cataaatggt aagtacccta tagcaagtat
     4561 attttctatg attaaacttg caactattaa ttgacctata ttatgcccta ttgcacctat
     4621 aatgcttatc cctattagtg ataaatcttt tattttactc gctaaataca taaataaaag
     4681 actcagataa gctcctccta tactaaatag tagatatgat aaagggcctg caaatattga
     4741 tgacaaaatt accctgatag taacaattat aacagtatct ttgacaccta acaacattaa
     4801 tgaaattaaa gttataatat tgctcaaacc caattttgcc cctggaaata taactataag
     4861 aggatttggt atatatgtct ctaatacata taaagctaaa ctatacccta tcataagacc
     4921 taaaaatgtc atttttctag ttttcattaa gttaactcct ccaaatttta tctatcatct
     4981 tacattataa tacaaaatat ataaaaacac ctaatttaga ctaaaatatt tttaatctat
     5041 ttagaataaa tattagttat ttcaatgtgc aattacctct ataaatcttg actttttgta
     5101 tcatacttgt tacaatttta atgataatga atttcattag gaggtgttaa taatgactgt
     5161 ttacgattta aaaataggag aaaaaggatt tattaatagt atagatggag atattaaatt
     5221 atctaaaaga ttgcttgcac ttggatgtat aaatagtact gaaatagaag ttaaaaaggt
     5281 tgccccactt ggagacccaa ttataattag atttagaggc tttgaccttg cgattagaaa
     5341 atctgatgct aaaaatattt ctttacaata atagaggagg agctacccgt gattaatgta
     5401 gcattattag gaaacccaaa tgtcggtaaa actactgttt ttaatctact tacaggttca
     5461 aatcaatatg taggtaactg gcctggtgtt actatagaaa aaaaagaagg atttcttgga
     5521 aaagagataa aggttgtcga tttacctggt atatatgcaa tggatacttt ctcaaatgaa
     5581 gaaaaggttt ctaaatcata tttagaaaat gaagatgttg atgtaatagt aaatgtagtt
     5641 gatgcttcta atttatcaag aaacctttac ttaacaactc aacttatgca atttaacaag
     5701 cctatagtta tattgcttaa tatgttagac attgcagaat ctaaaggagt taatatagat
     5761 gccaaaaaat taagtgaaga acttggagta attgttgttc caattatagc aaaaaagaaa
     5821 aatggtgttg ataggataga agaagagatt aagggagcta cgcaaaaagc ttttatatat
     5881 cagaaaaact ttggaagtga aacagaaaca tataaaaaat tagaatccat tttatcgaga
     5941 tgtacaaaaa ctacatatac acaaaagaaa tctatcagtg ataagataga caatatagtc
     6001 ttgaatccta tattagcata tccgatattt attggtgtat tgttcctctt atttaaattt
     6061 acctttgact gggtcggagg accactacaa gagggatttg ctagtcttat agaggcttat
     6121 atttctgcac ctgttagtga tatgttatct aactctagcc catggtttaa atcacttata
     6181 gttgatggaa taattggagg tgttggtggt actttaccat tcttcccttt aatatttaca
     6241 ttattctttg gtatatcgtt gtttgaagat agtggataca tgtcaagaac agcattttta
     6301 atggataaag ttatgagaaa ggttggtcta tctggtaaag cttttatacc tatagttatg
     6361 ggtatgggat gttcttctcc agctataatg gcaactagaa cattggaaag cgaaaaagat
     6421 agaagagtta cagctcttat tgcaccactt atgacttgtg gagcaaagct acctatatat
     6481 gcactatttg tagctatatt ctttccacat aatgctgctt tagtaactac atcactgtat
     6541 ttggtgggta tagttatggc aattgtagtt gcattattct taaataaaac agcctttaaa
     6601 acagaggctg aaccatttat attagaatta ccagaatata gaatccctac tatagatgca
     6661 cttattaaaa atacttggaa taaatcaaaa ggtttcttga taagagttgt tactgtcatg
     6721 tttgcaatgt cagtcgtaat ttggggactt tcttcattca atgtttttgg atatacagaa
     6781 gatataaatg taagcttctt ggctactcta ggtcatatta tatctcctat attcaaacct
     6841 cttggttttg atgattggag aacttcagtt gctattttaa gtggtcttgg agcaaaagaa
     6901 atcgtagtaa actctttaaa tatactatat ggtaatctaa ctgttgtctt accaacaata
     6961 tttaatggag ttactgcata tacattcttg atatttactg ctttatatac tccatgtata
     7021 gctgcacttg caactatgaa aaaagaatat ggcaataaaa tgatgtttac atcatttgca
     7081 tatcaattta tactagcatg gataatggct tttatagtta aaagtatagg tggagtacta
     7141 tttatgggta attcaataat ggaagctttg ataggtggaa taattatagt ccttgcactc
     7201 tttattctgt ttaataaatt caagtctaca aaaaacggaa atgtctgtag tggatgttct
     7261 atttgttctg gatgtccaag tgctaattct tgctcaagta aggaagacag caataaaaaa
     7321 aataatgcac actaatatat aaatatttta gtttaaaata agataaaagt gggtgtctca
     7381 aaattaactt tttagttcat gaggcactct tttttatata aaatcaaata tattttcatc
     7441 atttcaacag taaaaaagag cttatctagt aaaaaagagg cttatctcta ttttgagaca
     7501 acctcttttt ttgttactta ttcagtttct tgctacctaa cttcatgtgg aacctagtat
     7561 cttttggaac acttgggtct acacctctta atgtaggtat ttccccacat attagttgta
     7621 taggtactat aaaattaaat gtttgatagt aaggattatc tgtgatatca atctttaaat
     7681 ttttatcatt ttctgtaaca tctctaccta tagcaaatac attttccgtc caaccagaaa
     7741 gtacatcaat catcttagtt actctaggtt cttttcctgt atctagtata aatatagtag
     7801 aatcactatt tatagcatta tatataccat gtataaactc ttcaaactca tacccagtta
     7861 caggtattct cattgtttcc aataatttta atgctgcttc taatgtatct ccatatatat
     7921 cagagtgacc tattattctt atttctttag aattaactaa cttttctttg tttctttcaa
     7981 tccattgttt agagagctta tacactgctt caaatctatt aattgcgtct aatatcttat
     8041 ttatttcctc attgtacttt tcactagata ttataccttt ttctctagct atttgaagac
     8101 ctaataacat taagtttaac tttgtacaat aatatccttt tgttttagct ccagattttt
     8161 cttcaccaca atttactgtt aatatataat cagaaatctc atctattaaa gcattcttac
     8221 aacctgccat agatgctatt ttacagccct tatcttcagc taacttcata gcgttgtatg
     8281 tagaataact actcccacct tgagatacac ctactactag ggtattttca ttatcaaact
     8341 tgaatgtatc ttcagttatc ataaatggat acattttcac aacatctata tctaataaat
     8401 tttgtaaata tggttgcacc tgcactcctg agtgatagct agtacctgaa cctgttatta
     8461 taatcttttt tagatttgtt ctcttaactt cattaaataa gctatctgca ttagatataa
     8521 tttctctcat tctaactggt gtttctaaca tataatcttg tattgtcatt ttatacacct
     8581 tccttatcta tatattcaat aaattataat taatttctat aacaaaccta tagcatgtaa
     8641 agcgattcct gttactatag tgcctatagt taattttgtt acacttacct ttctctttaa
     8701 catgtagtat attacaaatg caaaggttaa aggtaacata ttaggtatta ttttatctag
     8761 tatatcttgt aaaattactt ctgcaccatt taagttgaat ttcagaggag tagttatact
     8821 caacatagtt gcaaccattc ctcctacaac gaataaacca acagttgtag ccatagacat
     8881 tattttctcc ataagtccct ctctttgtat tctttcaaga gaatttaccc ctacttgata
     8941 accatactta agtccaaata ttctaagggc aaatgctggt atattgtata atagtaagaa
     9001 taatagtggt ccaaagatat taccttcttt tgcaagtgat actcctactc ctgctgctat
     9061 aatcctaaat gttccccaga ataatgaatc accaattcct gcaagaggtc ccataagagc
     9121 tgttttaaca gcactaattg aactttcatc aaattctgga ttattagcat tctcttcttc
     9181 catagcggct gttataccta atatagcagg aactaccact gtcgttgtat taaaaatctc
     9241 caaatgcctt tctattgctt ttgcttgatt ttctttctta ttgtatagct tctttattgc
     9301 aggtaacatt gaataacagt aacctaagtt ttgcattctt tcgtaattaa atgcaccttg
     9361 aagagcaaat gaacgccaaa acatacttct taattctttt tttgttaatt tattcaaagt
     9421 caatctctcc ttccgttaaa gtattgattg ctaattgagg attttgatta ttttctttgt
     9481 tattgatata aaagtttagt acaaatgcta cacatactcc aaataaagct atagcagtta
     9541 tatctaatcc accataagat gctaacaaaa accctataaa gaaaaataca gacatctttt
     9601 ttgaaagtaa catatccata agcaatgcaa aacctactgc tggcaacaat gttcctgcaa
     9661 cacccaatcc gtctaatata actttaggta ttgcatttat taatgctgta actttatcag
     9721 caccaatcat aattgctaaa aaggttggaa ctgatgtact taaaaagaat aatattactg
     9781 gcaaccacat cattatggta actttcttaa aatcagcctg tttagcatag aaaactgcct
     9841 tttgagaaaa gtacgaattt attattctaa ctaatactcc aagagattgt gctaagactg
     9901 ctactggtac tgctactgct aaagcaactt ctgcaccatt acctgataat atagcaaaag
     9961 ctgtacctaa tacacctcct gttactacat ctggaggagt agctgcacct attcctgcaa
    10021 ttcccatcca aattaattca agctgtgcac caatcataat tcctgatttt atgtctccta
    10081 aaactaatcc tactaacata cctgtaacta ttggcctatc aagcatagat tgaccaaata
    10141 tacgcccatc tagtatacca actcctgcta taatagctaa catagtagct tgtactaaca
    10201 tattgaacct ccattttaac ttagtttaat ttacattaaa ttacattaca tttttgattt
    10261 tgttttgatt ttctaataac tcatttacat aaacaattcc attttttgct tcctctaatc
    10321 ctgatttaac tattagtttt gtatcctcct caactaataa aagtatagat aaaagcattg
    10381 gtaaatttac tcctgtcaat aattcaaatt tgaacccttg taaaagtaag tttgtacata
    10441 tgtttgccac acttccacca aacacatctg ttaagacaac aaattcttca ctatctttat
    10501 tatttgataa tatacttcta atttctttct cagcatcatc tgctgattta tccgttgtca
    10561 tacaaaaata ctcaatatta gttaatgaac caattattaa tttacttgtg tcaacaagct
    10621 ctctggacaa ttctccatgt gttgcaatta gaaatttttt cattctcttt ctcctaaatt
    10681 attttattaa atctgatagt tgtttctttt tgtctctagg taacattcta aattctatat
    10741 caatccctaa atcacctatt tgtttaaagt tatttatatc atcatcatca acagcaacta
    10801 aatctgtaag tttcttcttc ccttcctcat atcttaatcc tcctacattt atttctttta
    10861 atactcctcc tgaattttta gctacaacta aagcatcttt ggtatttttt actaacacta
    10921 atacattgct tttctttgaa gaagcaaatt tttctactat ttctccagat tcctctaccc
    10981 cccttatata taaagttaca ttgctaggtt tcgctaagtt cagtgacata gctttcattt
    11041 ggtcattttt tgcttcatca tttgcaacta gtattacatt tatacctagt gatgttgccc
    11101 atccatatgc aacctgacca tgtatcaatc tgtcatcaat tctcatcaaa gataccattt
    11161 tccccaaatc ctccatcata cattaaaatt tttattgttt atactctcat ttatctataa
    11221 aagcaaaaag tatgccaaat actggcatac ttttttaaat ttcattcact tattttgtaa
    11281 tcttgtattt tactgtggta gaccatagat aatattataa atatatccta tctctgaaat
    11341 tggtatttgc acactataac tcttttctag cacactaaat gcatttttta ttagttttac
    11401 ttcactatga tggtttttga ttaacaaatc catatcagta tactcttcaa tttcagtttg
    11461 tctaactaat ctttcaatca tacaacttaa gtgaacatat aaagaaatct ttttatcatt
    11521 tgaaagtttt ttcttttgaa tattttctat agcattaatt ccttcttcta ttctctctat
    11581 tatctttttt gaatctaaaa tagttagact atctattact ctaattaatg aaaaattctt
    11641 tacaatagaa tcatttatgt tctttatttt ttcattttct actactctgc taaatattct
    11701 aaaaacatca tcttctcctt ttcctgatat tatatcctct aataatataa aatctacccc
    11761 attcacattt ggattggcag ttcctactat agccatcaca tcatacattt caaaaactgg
    11821 ttctttatct cccatagaaa caagactatc ataatcataa ggtattattt tgacatcaac
    11881 tattccaatt aaactttcgg aaagtagatg ttggattttt atagcaatac ctatccctgt
    11941 aaaacaagat gatattatag catattcttt atttttttga ggataataca attgtatatt
    12001 aggtttagtt tcttcatcca taatttctgc aatctcttca atgtttttac cttgcattaa
    12061 taaatttcct acttctagtg cagaaatagt ggatatttgg tctataaata acattgggct
    12121 atttatctta ttctttaaat cttcatatat aagattaaga gagcccatat caaataatac
    12181 aattaaacca ttctttatcc tatctccctc tagatatcta gacatttgtt ttgatacatc
    12241 agcaatagta gcatctatag gcatatcaat agctgtaaat atatttttac ccaacatccg
    12301 attacataca ttcgccatac tactggcagt agcatatcca tgtgctataa tagtcgcatt
    12361 aacttgatta aatttcattc ttataattgt tgatttaata aatataatca ttatgattgt
    12421 atctacatta ttaagataca tatccaatct attcgttatt aatgttgata ttttacttat
    12481 tatagagtat tctttgtaac tctctttttt taaatatatt agtaatttat tttctaaagc
    12541 tttatactca tcagacaatt gataagattc gtccttcaaa taaagataag acgaaaatgc
    12601 caatacatta ttcccatcat attttatatt gttattaact tctaaatttc taaatatatc
    12661 ctgcattatc gatattataa gctccataag tacgttatta ttttcatcat tatttgaaaa
    12721 gactaaattg tccattagtc taatcattag attagaactc tttttactaa atttttcctt
    12781 tgttatttca tttttttcta gtctatcaaa gtaatctaaa cattttatga aactttgata
    12841 gattatattt cttttatttc ttccatttga catttcaata ctaaattgtt taggagaaaa
    12901 gataatgctt ttgcttttac cactttggaa ttgaaatata tctacatttt ctatataaag
    12961 atttctagga aggtcttgaa gagtaacaaa aatatttcca tttcttcttt gattttttgc
    13021 ataagctcgt ccacatgcat attttattac atttttacat tcacctatat tccccttgaa
    13081 ttttatcttt aaaatcgcat ttaatgtaat ttgagttatc tctataggca aaccaagtac
    13141 cttactttct tcataaataa aatgttctac aatctttctt ttttcaatag tccctctttc
    13201 ttctatattg ggaacataaa tatttatggg tattcttctt aaaaaggttt gtaaaaattc
    13261 agatagactt tctgttgtag caaatattaa tcttacccta gcttttctaa ttactccatt
    13321 ctctccaatc ctagaaaacg tacctgtatc cataaatgta aataactttt cctgaccttc
    13381 actatttaat ctatggactt catctaaaaa taaaacacca ccatctgatt gttctattag
    13441 acctgctcta gattcatttg ctccagtata tgctcctttt acatgcccaa ataatagact
    13501 agacaataac tccaaattat tataatactg cgcacagttt aacacattgt atggagaatt
    13561 tttttctaat acattactgc ttacactata tttgtatatt atcttggcta aaaaagtttt
    13621 tcctactcca ctttcacctg tcagcattat tgtaagtccg ccatttggat aaagtacagc
    13681 ggtttttatt tgttcgatta cttcttttaa gctattatca tatcctatga tactattaaa
    13741 cacagtctct tgctttaata atttacactc atttttaagt tcatctaaat tttcataaat
    13801 actttttttt gtaggtccta ctacatcatt tattttattt ttaggtaaaa aaataacagg
    13861 tctactgttt atctttataa gattatcaga ttttactaaa tcatttaata atctacttga
    13921 ttgagttcta cttaaattaa acttttttac tatatcttct gttattatgc cactttcttt
    13981 tttaagttca tcaaagctgt taaataatac acattcattt acaaaactta aaatttcatc
    14041 cctcatgttc aacctccaat acaaatatca ataatactat aatattagta tatcatttat
    14101 atatttatga aaaagataat tatattccta tcttgattct cttttgtaag gttgtaaaat
    14161 caaacttttt ataagtataa aatctagatt ttttaacata atctcaaggt tcttatcttt
    14221 ccatatatct g
//
LOCUS       DAJMZY010000105        14160 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.106, whole genome shotgun sequence.
ACCESSION   DAJMZY010000105 DAJMZY010000000
VERSION     DAJMZY010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 14160)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14160)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14160
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.106"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            479..1372
                     /locus_tag="OE968_003035"
     CDS             479..1372
                     /locus_tag="OE968_003035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfide/dihydroorotate dehydrogenase-like
                     FAD/NAD-binding protein"
                     /protein_id="HCP7220295.1"
                     /translation="MSNKIVSKRQLTDSIYLMEIEAPRVAKSSQPGQFIIIKNDEKGE
                     RIPLTIADYDREKGTVTIVFQTVGASTKKLAMFEENDFVMDFVGPLGQASEFIHEDIE
                     ELRNKKILFVAGGVGSAPVYPQVKWFKEHGLDVDVIIGARTKELIILEDDMKKVAKNV
                     YVSTDDGTYGFNGRVTDLLKDLVDNQGKKYDQAIVIGPMIMMKFMCQLTKELNIPTIV
                     SLNTIMIDGTGMCGGCRVSVGNETKFACVDGPEFDGHLVDFDQAMRRQSMYKTQEGRA
                     MLKLEEGDSHHHSNCGCGGNK"
     gene            1372..2766
                     /gene="gltA"
                     /locus_tag="OE968_003036"
     CDS             1372..2766
                     /gene="gltA"
                     /locus_tag="OE968_003036"
                     /EC_number="1.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent glutamate synthase"
                     /protein_id="HCP7220296.1"
                     /translation="MDAKKVKVPVREQEPAVRATNFDEVCLGYNKEEAMAEANRCLAC
                     KKPKCVGGCPVGIDIPGFITKIKEDDIEGAAKVIAKSSSLPAVCGRVCPQESQCEGVC
                     ILGIKSDAVSIGKLERFVADWSKENDINLSDTEPKKNQKVAVIGSGPAGLACAGDLAK
                     KGYDVTIFEAMHEPGGVLTYGIPEFRLPKQAVVQPEIDNIRKLGVKIETNVIVGKTIT
                     VDELIEDEGFEAIFIGSGAGLPMFMNIPGENANGVFSANEFLTRVNLMKAYRDDYDTP
                     ISSGKKVAVVGGGNVAMDAARTALRLGSESYIVYRRSEKELPARAEEVHHAKEEGIIF
                     NTLTNPKEILVDENGYVKGMVCIRMELGEPDDSGRRRPIEIEGSEFVLDVDTVIMSLG
                     TSPNPLISSTTKSLDINKKRCLITDENGQTSKEGVFAGGDAVTGAATVISAMGAGKTA
                     AASIDEYLKAKVNA"
     gene            3132..5351
                     /locus_tag="OE968_003037"
     CDS             3132..5351
                     /locus_tag="OE968_003037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HCP7220297.1"
                     /translation="MKKREKVFDGLVFKHILILLILLVLIDLTSTIIYASNSMEITSR
                     NMIEASKRELENYLEVNISLLKALSQDDRFSNGETSLIEKGKLLSPYQKEYNLFMIGI
                     TDTKGNASSTYRENVNSIKDKPSFEKAIKTKQVVVSDIEVSNVTGDKVFIIYVPIVKN
                     NEMIGTIFASFYFQDVNNLISRSNFDDSIKFLMIDKDYTIISHPNKKYVNDKSKMLDL
                     EGNIIGTTKSEILKNINKKCQGDFLSWDNWRLYNVKYTNIKWTNWTLVSKCNIFKNFK
                     NLIVNFMIKLYFYIVIFMILWKLSNAKLIEQLKKLAYYDSLSGIKNKEKFRKDSMYIL
                     KNYYQDNFYLVQLDVNKFKYINEMFGYAEGNKILIHISQVLNNNTNKYEICARMDNDH
                     FILLIACNTEDELLNRLSKINKEICNLNTTNSSKYKIVMSSGIYKITKKDDIKKIDLL
                     IDRANIAAKSKKEKYEHSYSFFNEDTRNRLYKEKRLEDNMNKALEKGEFIVYYQPKYS
                     LDDVNEIEGAEALIRWNSPEFGFISPIDFVPLFEKNGFIVNIDMFVFEEVCKTLNKWI
                     NKGYTPVPISVNMSRVHLYRDNFIENITDLISKYNISPEFIELELTESVVFDNLNILI
                     DIMKKIKEIGFLISMDDFGSGYSSLNLLKDLSFDILKLDRGFLIETTDTKRGKIIISK
                     IVEMAKAIDIKVICEGVETYEQVEFLKEIGCDKVQGYLFAKPMVLDEFEKHLNFKFD"
     gene            5498..6244
                     /locus_tag="OE968_003038"
     CDS             5498..6244
                     /locus_tag="OE968_003038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014466367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCP7220298.1"
                     /translation="MNILSIRNISKTYCGNIPFKALDKVSLNIEKGEFVSVMGPSGSG
                     KSTLLNIISTVDRQSEGEVVLDGYDVSKLKGEKLAEFRRKQLGFVFQDFNLIDTLTVG
                     ENIMLPLTLEGASIKDMNIQTKSISKFLGIDKILDRKTYEISGGQAQRCAIARAIINK
                     PAILLADEPTGNLDSKSTDDVLKLFTRINKEQKVTTLMVTHEAYSASYSDRVIFIKDG
                     CIYTEIKKSESSNSFYSDILAVLSQIGGVR"
     gene            6244..8124
                     /locus_tag="OE968_003039"
     CDS             6244..8124
                     /locus_tag="OE968_003039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCP7220299.1"
                     /translation="MDFRKFAYNNIVRNFRAYLAYFLSSVFSIMIFFVFAVSMFHPII
                     TKSGMQSGSTAFMALMTSELIIFGFSLLFILYSLGNFLKYRLKDFGVLMIIGMSNRQL
                     KKLILIENLIIGFLAVMLGILLGLSISKLFLLYLSKLFYMNLTEFYFPVKAMLLTIVS
                     FMILFLITGPMSLKLLSKKSILELLVGTKKPKKEIKSSKLFGIIGVICLILGYAMILF
                     GNKLKINGGMYTTALLITLGIFLFFSQFTILILKYLKNKEKFYKNKVNMLLISNLIYK
                     LKDNTRLLFLITILLSATLVAFTTTSTLVSSQGEASKNNFPMVYSYFSEHNNEKEYEE
                     LQQIREAIKGYDYKELSFPVLKYNREVLLSVKNYNKLSKELGLDKISSKLEKYEGIII
                     PSSNSQEHINSLKQLKNYSIKNLNIEVKKSKNKIIFPTGLFSKVVVISDDLYNEVKGE
                     FSKINFHGFDYKNWQSSAKITENLKEKHFNLDREYNRSYFLTLPDMYLVELQQSKILQ
                     FMGVFIGVILFIAVFSFLYFRLYTDEIEDNVKYKKLSKIGLSFKNMNKIVSIEIGTLF
                     FIPYFIAIINSIISLLFLNQVLNNSFKLENLGILLLISSIYSLYFYLLKKNYTRKVWF
                     FD"
     gene            8243..9634
                     /locus_tag="OE968_003040"
     CDS             8243..9634
                     /locus_tag="OE968_003040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HCP7220300.1"
                     /translation="MENQQLLGTERISKLLLKYSIPAIIGMLVNSLYNVVDRIFIGNI
                     PGVGPLAITGLGVTMPIMTIILAFGMLIGIGTTTTISIKLGQGKVEEARKLIGNAMTL
                     SVITGIIIMILGILFANKILTLFGASENTLIYAKSYINIILLGTVVNLLSFSLNHSIR
                     ADGSPKISAGIMIVGCLTNIVLDWILIFGFNLGIQGAAIATVTSQALTAILTIGYYIS
                     GKSNLRFSKSNLKLDKKLIKAVFAIGMSPFAMQLAASLVQVISNIALKTHGGDLAIGA
                     MATISSIAMVFLMPIFGINQGAQPIIGFNYGAEKYDRVKKAYLGSLVVATIILCMGMV
                     VVMLFPEAIIGIFNKDPELMNISVNGLRIYLLMLPIVGLSVTGTNFIQSIGKAKMAML
                     LSLLRQVILLIPAVLILPTFLGLQGVWTAQPVSDFIATVITGIVVFRELKRYTPKTEK
                     LNENERLNEITTE"
     gene            9741..10781
                     /locus_tag="OE968_003041"
     CDS             9741..10781
                     /locus_tag="OE968_003041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HCP7220301.1"
                     /translation="MEFTKKSKLKNMYVNMNVARMLSKINEYKGRQLLYKKQPKEILE
                     NLEKKSLVDCSESTYIGNQRDSSNFNLEKLISNEVTPRSREELSIVEYRDVVKTINSA
                     YESIPISSQTILELHGYLYKFSSTRGGSYKSDNDFIEHNLKPSEFISTDSSVNKVEKA
                     VEEICEAYNTLIEEDEIDILILISAFVLDFILIHPFKEGNIKMARVLILLLLNKNGYE
                     VGRYISLGKIFDDSSYEYYSNLNYLKASIGSEKADMNAWIEYFLETILTAYEKLDDSL
                     NISDKKRQTKTSRIEKIINSTLGYFTKEDIRDLCPDIPEPTINRVFNNLRKQDKIEVV
                     ARGRSAKWKKKY"
     gene            11270..11923
                     /locus_tag="OE968_003042"
     CDS             11270..11923
                     /locus_tag="OE968_003042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HCP7220302.1"
                     /translation="MKKKLLYINVNSKPEDLSSSKTVARKFINKFMEKNKDFEVEEID
                     LYKEHIPRLEYQYFEKRNSIVSEENAKNLDDKDRKELTKIRNLCDQFVNASVYVIAAP
                     MWSLSFPAPLKEYIDCIIQDGKTISFEGNDKPQGILNDIDRSMVYIQSSGGHIPWVLK
                     PVMNKGLNYVESIMKFIGIKKFDELLVDGTGTSEEERQAAIEKASEKIDGIIDGMKF"
     gene            11999..12208
                     /locus_tag="OE968_003043"
     CDS             11999..12208
                     /locus_tag="OE968_003043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220303.1"
                     /translation="MREEKSNEKYDCYWCNQENNFCVEIKDNIVMIDDGTGTLKQAVF
                     IGYKQIQINLNCSHCQNLNRIKLNL"
     gene            complement(12348..12914)
                     /locus_tag="OE968_003044"
     CDS             complement(12348..12914)
                     /locus_tag="OE968_003044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HCP7220304.1"
                     /translation="MMNNELNTIILETLNNADITSNDIPSIDLYMDQIISLIDNKLSA
                     NKRFESDKILTKTMINNYSKEGLIKPVKGKKYTKEQILQMIIIYSMKNTLTIQEIKRI
                     LHGVYEKDNFSEKDLVSCYEKFMLIKENQRKNIPDFIESNFENISINPENKDDLLIAL
                     LSLTSMADQLKNISEKLVDRYFPDITKK"
     gene            13075..13728
                     /locus_tag="OE968_003045"
     CDS             13075..13728
                     /locus_tag="OE968_003045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HCP7220305.1"
                     /translation="MYQFFLKGRDPISSLTHFIGACLSLLATIILVFQSVTLQETSLL
                     MIVSVSVFGLSLIALYSASSYYHFLKGTPEQELFFRKVDHAMIYVLIAGSYTPICLNF
                     MEKKEGIIFVTAIWIVAFIGIIIKIFWMDAPRWLSTSIYLLMGWAIVFDINAFNSIPK
                     DCLRLLIMEGVSYSIGAIIYIIKKPNISPEFGFHEIFHIFIMIGSLFHFLAVLLYVL"
     gene            complement(13886..14062)
                     /locus_tag="OE968_003046"
     CDS             complement(13886..14062)
                     /locus_tag="OE968_003046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220306.1"
                     /translation="MYKYDDYVNLTNDLDLPVEIRNKCVRIVSVSENLEDIIIVHKFK
                     LYVVNEKYIKGIME"
BASE COUNT         5547 a         1399 c         2379 g         4835 t
ORIGIN      
        1 aatattgaaa attttagata tataataaaa taagagtata ttttatacaa tatgaaagct
       61 ggtattgcaa tagattaaag ccttatacac gtttagtttt taaagaaatt agtgttatta
      121 tgaaaaccta agttaattta ttaaataaat aattgaataa aaaaatttta ttatgtattt
      181 ataaaatttt tgttacaaat ttggcataat atagtatact ttaagtgtgt attaggttaa
      241 atctataaca aattagacgt atgatataga cttagtgttt attggcattt acaagaaatt
      301 tgttaatatc aactatttgt agtttgggca gttataatta ttataggggg gatgtccaat
      361 acaaaacaat caaccaagaa ctaatattat attataaaga gttatagttt tgtgtgttta
      421 tgtttttaat taaatttaaa gtgggaaaaa tatatttgtt agaatggaga atagcgagat
      481 gagtaataaa atagttagta agagacaatt aacagatagt atttatttaa tggaaataga
      541 ggcacctaga gttgcaaaat cttctcaacc aggtcaattt ataataatta aaaatgatga
      601 aaaaggagag aggattcctc ttacaatagc tgactatgat agagaaaaag gaacagtaac
      661 tattgtattc caaacagttg gtgcttcaac taaaaagtta gcaatgtttg aagaaaacga
      721 ttttgtaatg gattttgtag ggccattagg acaagcaagt gaatttatac atgaagatat
      781 agaagaatta agaaataaaa agatattatt tgtagctggt ggagttggtt ctgctccagt
      841 ttatccacaa gttaaatggt ttaaagagca tggattagat gtagatgtaa taattggtgc
      901 aagaactaaa gaattaatta tattagaaga tgatatgaaa aaagtagcta aaaatgtata
      961 tgtatcaaca gatgatggta catatggatt taatggaaga gttacagacc tattaaaaga
     1021 tttagttgat aatcaaggta aaaaatacga ccaagcaata gtaattggac caatgataat
     1081 gatgaaattt atgtgccaat taactaaaga actaaatata cctactatag taagtttaaa
     1141 tacaataatg atagatggaa caggtatgtg tggtggttgt agagttagtg ttggaaatga
     1201 aactaagttt gcatgtgtag atggtcctga atttgatggt catttagttg attttgatca
     1261 agcaatgaga agacagtcta tgtacaagac tcaagaggga agagctatgc taaaacttga
     1321 agaaggcgat agtcatcatc atagtaattg tggatgtgga ggtaacaaat aatggatgct
     1381 aaaaaagtaa aagtaccagt tagagaacaa gaacctgctg tgagagcaac aaattttgat
     1441 gaagtatgct tagggtataa taaagaagaa gctatggcag aagctaatag atgtttggct
     1501 tgtaaaaaac caaaatgtgt gggtggatgt ccagtaggaa tcgacatacc agggtttata
     1561 acaaaaatta aagaagatga tatagaaggt gctgctaaag taatagctaa gagcagttca
     1621 ttaccagctg tttgtggtag agtatgccca caagaaagtc aatgtgaagg tgtatgtata
     1681 cttggaataa aatcagatgc tgtatcaata ggtaaattag aaagatttgt agcagattgg
     1741 tcaaaagaaa atgacataaa tttatctgat acagagccta agaaaaatca aaaagtagca
     1801 gtaataggaa gtggtccagc aggtctagct tgtgctggtg atttagctaa aaaaggctat
     1861 gatgtaacaa tctttgaagc aatgcatgag ccaggtggag ttttaactta cggaatacct
     1921 gagtttagac ttccaaaaca agctgttgtt caacctgaaa tagacaatat aagaaaatta
     1981 ggtgtaaaaa tagaaactaa tgtaattgtt ggtaaaacaa ttacagtaga tgaacttata
     2041 gaagatgaag gatttgaagc tatattcata ggttcaggag ctggtcttcc aatgtttatg
     2101 aatataccag gggaaaatgc aaatggagta ttttctgcaa atgagttttt aactagagta
     2161 aacttaatga aggcttatag agatgattat gatacaccta ttagttctgg taaaaaagtt
     2221 gctgtagtag gtggtggaaa tgttgctatg gacgctgcta gaactgcatt aagattaggt
     2281 tcagaatcat atatagttta tagaagaagt gaaaaagagc ttccagcaag agctgaagaa
     2341 gttcatcatg caaaagaaga aggcattata tttaatacat taacaaatcc taaggaaatt
     2401 ttagtagatg aaaatggata tgttaaaggt atggtttgta taagaatgga attaggagag
     2461 ccagatgatt ctggaagaag aagacctata gaaatagaag gttctgaatt tgtacttgat
     2521 gtagacacag ttataatgtc acttggaaca agcccaaatc cactaatatc ttctacaaca
     2581 aagagtcttg atataaataa gaagagatgc ttaataacag atgaaaatgg tcagacttct
     2641 aaagagggtg tatttgcagg tggagatgct gttactggag cagcaacagt aatatctgca
     2701 atgggtgctg gtaaaacagc agcagcatca atagatgaat atttaaaagc aaaagttaat
     2761 gcttaatttg taaattaaag agagggtgtc tcaaaatgaa ctttttagtt catgaggcac
     2821 tctttttgta caaaatcaaa tatgttttaa tcatttcaac aatgaaaatt tcattcctgt
     2881 agaaagtcta acttttaggt cttagtacaa tctctatttt gatgtagcca cttttttaga
     2941 tggtttaata atttatcagt tattattgta atatttgata ctaagtaaca taactttgtc
     3001 taactatgat aaaatagtta tacaataaag gtcttgtaag gagtgaataa tgtgtggcta
     3061 ataaaatcag atttgtcaaa tctaacatta aataatagaa aaataaattg tgtaattaat
     3121 ggtattttaa tatgaaaaaa agagaaaaag tatttgatgg gctagttttt aagcatatat
     3181 taatcttatt aatactatta gttttgattg atttaacaag taccatcata tatgcaagta
     3241 actctatgga aattacttct agaaatatga ttgaggcatc aaaaagagaa cttgaaaact
     3301 atttagaagt aaacatatct ttattaaaag ctcttagtca agatgataga ttttctaatg
     3361 gtgaaacatc actaattgaa aagggaaaat tattaagtcc atatcaaaag gaatataatc
     3421 tttttatgat tggtataaca gatacaaaag gaaatgcttc aagtacatat agggaaaatg
     3481 ttaactcaat aaaagataag cctagttttg agaaagcaat taaaacaaag caagtagtag
     3541 tttcagatat tgaagtcagt aatgtaacag gtgacaaagt atttatcata tatgtaccaa
     3601 ttgtaaaaaa taatgagatg attgggacca tttttgcttc tttttatttt caagatgtaa
     3661 ataatttaat aagtagaagc aattttgatg attctattaa atttctaatg atagataaag
     3721 attatactat tatttctcat ccaaacaaaa aatatgtaaa tgataaaagt aagatgcttg
     3781 atttagaagg gaatattata ggaaccacta aaagtgaaat cttaaaaaat ataaataaaa
     3841 aatgtcaagg tgatttttta tcttgggata attggagatt atataatgta aaatatacga
     3901 acataaagtg gactaattgg actttagtat caaaatgtaa tatatttaag aactttaaaa
     3961 atctaatagt taattttatg ataaagttgt atttttatat agtaatattt atgatattgt
     4021 ggaaattaag taatgctaaa ttaatagaac aacttaaaaa attggcttat tatgattctt
     4081 taagtggaat aaaaaataaa gaaaagttta gaaaagattc tatgtatatt ttaaagaatt
     4141 attatcaaga taatttttac ttagtacaat tggatgtcaa taaatttaaa tatataaatg
     4201 agatgtttgg atatgctgaa gggaataaga tattaattca tatatcacag gttttaaata
     4261 ataatacaaa taaatatgaa atttgtgcta ggatggataa tgaccatttt atattgttga
     4321 ttgcttgtaa cactgaagat gaacttttaa atagattatc taaaataaat aaagaaattt
     4381 gtaacttaaa tactactaac tcatctaagt ataaaattgt tatgtcaagt ggaatatata
     4441 agattactaa aaaggatgat attaaaaaga ttgacttgtt aattgataga gcaaatattg
     4501 cagcaaaaag taaaaaggaa aaatatgaac attcatattc attttttaat gaagatacaa
     4561 gaaatcgatt gtacaaggaa aaacgattgg aagataatat gaataaagct ttagaaaaag
     4621 gtgaatttat agtatattat caacctaagt atagtttaga tgatgtaaat gaaattgaag
     4681 gagcagaagc cttgataaga tggaatagtc cagaatttgg gtttatttca cctatagatt
     4741 ttgtaccttt atttgaaaag aatggtttta ttgtaaatat tgatatgttc gtgtttgaag
     4801 aagtatgcaa aacattaaac aagtggataa ataaagggta tactcctgta ccaatctctg
     4861 taaatatgtc tagagttcat ttatataggg ataattttat agaaaatata actgatttga
     4921 taagtaaata caatatatct cctgagttta ttgagcttga actaacagaa agtgttgtgt
     4981 ttgataattt aaatatattg attgatataa tgaaaaagat taaagagata ggattcctta
     5041 tatcaatgga tgattttggt tcgggatatt catctttaaa tctgttaaaa gacctttctt
     5101 ttgatatttt aaaattagat agaggatttt taatcgaaac aacagataca aaacgtggaa
     5161 aaattattat ttctaagatt gtggaaatgg caaaagcgat tgatattaaa gtaatctgtg
     5221 agggcgtaga aacttatgaa caagtagagt tcttgaaaga gataggttgt gataaggttc
     5281 aaggatactt atttgctaaa cctatggtat tagatgaatt tgaaaaacac ttaaacttta
     5341 aatttgatta atcattaata attattagac tataagatac cctaacaact tacttacaaa
     5401 tatgtaagtt aattgttagg gtatttttat ggttaaagta gtatattcac gatattatgg
     5461 tattgtagta aaaataaaaa attatggaga atataaaatg aacatattga gtattagaaa
     5521 tatatcaaaa acatattgtg gaaatattcc atttaaagca ttagataagg ttagtctaaa
     5581 tatagaaaag ggagaatttg tgtctgttat gggaccatct ggaagtggta aatctactct
     5641 tttaaatata atatctacag ttgatagaca gagtgaaggt gaggttgtat tagatggata
     5701 tgatgtaagt aaattgaaag gagaaaaact tgctgaattt agaaggaaac aacttggttt
     5761 tgtatttcag gattttaatt tgattgacac tttaactgtt ggcgaaaata ttatgttgcc
     5821 acttacacta gagggggcaa gtatcaaaga tatgaatata caaactaaaa gtatatctaa
     5881 atttttagga atagataaaa ttttagatag aaaaacctat gaaatttcag gaggtcaagc
     5941 tcaaaggtgt gctattgcta gagctattat aaataaacct gccatacttc ttgcagatga
     6001 gccaactgga aatcttgatt caaaatctac tgatgatgtt ttgaaattat ttactaggat
     6061 aaacaaagaa caaaaggtaa caacacttat ggtaactcat gaagcatata gtgcaagtta
     6121 ttcagataga gtaattttta taaaagatgg ttgtatatat acagaaataa aaaaatctga
     6181 aagcagtaat tctttctatt ctgatatact agctgttttg tctcaaatag gaggtgtaag
     6241 atagtggatt ttagaaagtt tgcttataat aatatagtta gaaatttcag ggcatattta
     6301 gcatattttt taagttctgt tttttctata atgatatttt ttgtttttgc agtgtctatg
     6361 ttccatccaa ttataacaaa atctggaatg cagagtggtt ctactgcatt tatggctctt
     6421 atgacttcag aattaataat attcggtttt agtctacttt ttatattgta ctctttagga
     6481 aatttcttaa aatatagatt gaaagatttt ggagtattga tgataattgg aatgagtaac
     6541 agacaactga aaaaattgat attaattgaa aatttgataa taggattttt agcagtgatg
     6601 ttaggaatat tacttggttt atcaatttca aaattgtttt tattgtattt aagcaaactg
     6661 ttttatatga atttaactga attttatttt ccagtaaaag caatgctatt gactattgta
     6721 tcatttatga ttttattttt gataacagga ccaatgagct taaaattatt gagtaaaaag
     6781 agcattttag agcttttagt aggtacaaaa aagcctaaaa aagagataaa atcttcaaag
     6841 ctatttggaa taattggtgt aatatgtctt atattaggat atgctatgat actatttggc
     6901 aataagttaa aaataaatgg aggtatgtat acaacagcac tattaattac tttggggata
     6961 tttttatttt tttctcaatt tactattttg atattaaagt atttaaaaaa taaagaaaaa
     7021 ttttataaga acaaagtaaa tatgttactt ataagtaatt tgatatataa attaaaggat
     7081 aatacacgat tgttattttt aataacaata cttttatcgg ctactttagt agcatttaca
     7141 acaacttcaa cacttgtaag ttctcaagga gaagcttcta aaaataattt cccaatggtt
     7201 tactcatatt tttcagagca taataatgaa aaagaatatg aagaactaca acaaattaga
     7261 gaagcaatca aaggatatga ttataaggag ttaagttttc ctgtacttaa atataatagg
     7321 gaagtcttac taagtgtaaa gaattataac aaattatcaa aggaattggg attagataaa
     7381 attagttcaa agttagaaaa atatgaaggg attataattc ctagtagcaa ttcgcaagaa
     7441 catataaatt ctttaaaaca attaaaaaat tatagtataa aaaatttaaa tatagaagta
     7501 aaaaaatcaa aaaataaaat aatttttcct acaggactgt ttagtaaagt tgtggttata
     7561 agtgatgact tatacaatga agtaaaaggt gaattttcaa aaattaattt tcatggattt
     7621 gattataaaa actggcaaag cagtgcaaag ataactgaaa atttaaaaga aaaacatttt
     7681 aatttggata gagaatataa caggtcatat tttttaacat taccagatat gtatttagta
     7741 gagttacaac aaagtaaaat tcttcaattt atgggtgttt ttataggagt gatattattt
     7801 atagcagttt ttagtttttt atacttcaga ttatatacag acgagataga agataatgta
     7861 aagtacaaaa aactatcaaa aataggtcta tcttttaaaa atatgaataa gattgttagt
     7921 atagagatag gtacattgtt ttttataccg tattttatag caattataaa tagcataatt
     7981 tctttactgt ttttaaatca agtattaaat aatagtttta agttagaaaa tttgggtata
     8041 ttactactga tatcatctat atattcactt tatttttact tattaaaaaa aaattatact
     8101 agaaaagttt ggttttttga ttaaagtggt atataataga tatataaatt aatatttaaa
     8161 aagtagttaa tattagggga gggcatttgc acctcccttg taatatgtgg aaaattgaat
     8221 attagaagaa ggaggagact tgatggaaaa tcaacaatta ttaggaacag aacgaattag
     8281 taaattacta ctaaaatatt ctataccagc tataataggt atgttggtaa atagtttata
     8341 taatgtagta gatagaattt ttattggaaa tataccaggg gttggaccac ttgcaataac
     8401 aggtcttggt gtaacaatgc caataatgac aataatactt gcatttggga tgttgatagg
     8461 tataggaact actactacca tatcaataaa acttgggcaa ggtaaagtag aagaggcaag
     8521 aaaacttata ggaaatgcaa tgacgttatc tgtaataaca ggaattatca taatgatact
     8581 tggaatatta tttgcaaata aaatacttac attgtttgga gcaagtgaaa atactttaat
     8641 atatgcaaaa tcatatatca atattatatt attaggtaca gtagtaaatc ttctttcctt
     8701 ttctttaaac cactcaataa gagctgatgg tagtcctaaa atttcagcag gaataatgat
     8761 agtaggatgt ttaactaata tagttttaga ctggatatta atatttggat tcaatttggg
     8821 aatacaagga gctgcaattg ctacagtaac ttctcaggct cttacagcta ttttaactat
     8881 agggtattat ataagtggaa aatcaaactt acgattcagt aaatctaatc taaaattaga
     8941 taaaaagcta ataaaagcag tgtttgcaat aggtatgtcg ccatttgcta tgcaacttgc
     9001 agcaagttta gttcaagtaa tatcaaatat tgcacttaaa actcatggtg gagatttagc
     9061 tataggggct atggctacta tttcttctat tgcaatggta tttttgatgc ctatctttgg
     9121 aataaatcaa ggagcgcaac ctattatagg tttcaattat ggagctgaaa aatatgatag
     9181 ggttaaaaaa gcatatttag gttcattagt agtagctact ataattttat gtatgggtat
     9241 ggtagtagtt atgcttttcc cagaagctat tataggtata tttaataaag accctgaact
     9301 tatgaatata tctgttaatg gattaagaat atacttactt atgttgccaa ttgtaggctt
     9361 atcagttaca ggaacaaact ttatacaatc tataggaaaa gcaaaaatgg ctatgttatt
     9421 gagcctttta agacaagtaa ttttattgat accagcagta ttaattcttc ctacattctt
     9481 aggtttacag ggtgtatgga cagctcaacc agtgtctgat tttatagcta cagtaattac
     9541 aggtatagtt gtatttagag aattaaaaag atatactcct aaaactgaaa aattaaatga
     9601 aaatgaaaga ctaaacgaga taactactga gtaaaaatat aaattcagat aattgagcaa
     9661 gaaattgcaa aaaatacgat tatatgataa aataaaaccg ctgtcaagga taagagaaat
     9721 tctaattatg gagtgatttt atggaattta caaagaaaag caaattaaaa aatatgtatg
     9781 taaacatgaa tgtagctaga atgttgtcta agataaatga gtataagggt agacaactgc
     9841 tttacaaaaa acaaccaaaa gaaattttag aaaacttaga aaaaaaatct ttagtagatt
     9901 gttctgaatc tacatacatt ggaaatcaaa gagatagtag taattttaat ctagaaaagt
     9961 tgataagtaa tgaagttaca cctagaagta gagaggaatt gagtattgtt gaatacagag
    10021 atgtggtaaa aactattaac agtgcttatg agagtattcc catcagttca caaacaattc
    10081 ttgagcttca tggatactta tataaatttt catctactag aggaggaagt tataagtcag
    10141 ataatgattt tattgaacac aatttaaaac ctagcgaatt tataagtact gattcaagtg
    10201 tcaataaagt tgaaaaagct gtagaagaaa tatgtgaagc ttataataca ttgatagagg
    10261 aagatgaaat tgatatatta atattaattt ctgcatttgt gttagatttc atattgatac
    10321 atccattcaa agaaggtaat ataaaaatgg cgagagtact tatcctattg ttactaaata
    10381 aaaatgggta tgaagttgga agatatataa gtttaggaaa gatatttgat gatagttcat
    10441 atgaatatta tagtaattta aattatttga aagcctcaat aggtagtgaa aaagcagata
    10501 tgaatgcatg gattgagtat tttttagaga cgatattaac tgcatatgag aagctggatg
    10561 atagtttaaa tatatctgat aagaaaagac aaacaaaaac tagtagaata gagaaaataa
    10621 taaattctac ccttggatat tttacaaaag aagatataag agatttatgt cctgacattc
    10681 cagaacctac tataaataga gtttttaata atctaagaaa acaagataag atagaagttg
    10741 ttgcaagagg aagaagtgca aaatggaaga aaaaatatta aaaaatgttt agataactaa
    10801 aatggtatag tgttttacac tataccattt ttaatgtcat tagcatgagc aataatttaa
    10861 caacttaagc aatatcaatt ttatttattg attatttttg aactgaaaaa tggcgttata
    10921 tggtatacct cagtggtaat taattttgga tgagaagata taatattaca gaatatatta
    10981 ggagtatatg tagaaaaaat ataataaaag tgtgaggctt agtaattaac aaattatgtg
    11041 gcttcacact tttttataaa ataaagatac ttagcagaat aatattttag ttgatatgtt
    11101 tataagatgg tacttgtttg ggtaaaagta taaatagtaa aaaagtagaa gtaatgtgta
    11161 taaaaacata agttacattc tgtaataata gttattttat aattcaacaa aagaatagaa
    11221 tgggtatatt tgtgaaataa taatataaaa taatcttagg agtgagctta tgaagaaaaa
    11281 attattatat ataaatgtaa attcaaaacc tgaagactta tcttcaagta aaactgtagc
    11341 aagaaaattt ataaataaat ttatggaaaa aaataaagat tttgaggttg aagagataga
    11401 cctttataaa gaacatatac caagacttga gtatcagtac tttgaaaaaa gaaatagcat
    11461 agttagtgaa gaaaatgcta aaaatttaga cgataaggat agaaaagagc ttacaaagat
    11521 tagaaatctt tgtgaccaat ttgtgaatgc aagtgtttat gtaatagcag cacctatgtg
    11581 gagtttatct tttccagcac cacttaaaga gtatatagat tgtataattc aagatggaaa
    11641 aactatatct tttgaaggca atgataaacc acaaggaatt ttaaatgata ttgatagaag
    11701 tatggtatat atacaatctt ctggtggaca cataccatgg gtgttgaagc cagttatgaa
    11761 taaagggtta aattatgtgg aaagtattat gaaatttata ggaattaaaa aatttgatga
    11821 attgttagta gatggaactg gaactagtga agaagaaaga caagctgcaa tagaaaaagc
    11881 atctgaaaaa atagatggta taatagatgg gatgaaattt taattataat attttattaa
    11941 aaatataaag gaaaaacctc ttttaatgta gaaacttata ttgaaggagg cgagaatcat
    12001 gcgagaagaa aaaagtaatg aaaagtatga ttgttattgg tgtaatcaag agaataattt
    12061 ctgtgtagaa ataaaagata atatagtcat gatagatgat ggcactggta cgttaaaaca
    12121 agccgttttc atagggtata aacaaatcca aattaattta aactgttcac attgtcaaaa
    12181 cttaaataga ataaaattaa atttgtagaa ttttaaaatg gaaattattg aaggaattaa
    12241 aaatagaaag tgttaatatt tagactgaaa attatatttt atacaataaa agtttattta
    12301 aataacattg tattttaata tttattttca gtcttacttt attaaaatta ttttttggtt
    12361 atgtctggaa aatatctgtc tactaatttt tctgaaatat tttttaattg gtcagccatt
    12421 gaagtcagac ttaataaggc tatcaataaa tcatctttat tttctggatt tatactaata
    12481 ttttcaaaat tagactctat aaagtccggt atattctttc tttgattttc ttttattaac
    12541 atgaattttt cgtaacatga aactaaatct ttttcactga aattatcctt ttcatacaca
    12601 ccatgtaaga ttcttttaat ttcttgtatt gtaagtgtat ttttcataga ataaataatt
    12661 atcatctgta aaatttgttc tttagtatac ttttttccct taactggttt gattaatccc
    12721 tctttgctgt aattatttat catggtttta gtaagaattt tatcactttc aaatctttta
    12781 ttagcagaaa gcttattgtc aattagagaa ataatttgat ccatatataa gtcaatagat
    12841 ggaatatcgt ttgaagttat atctgcatta tttagtgttt ctagtattat agtattaagt
    12901 tcattattca tcatatgtta cctccataat atatataata cactaaatta gaaagtaaaa
    12961 caatattaag gcttgtaaaa aaaacataaa gtggtataat taaatatata atatagtaat
    13021 caaaactata tttatgaatc tgatttttaa aatacataat tgtaggagga cgaaatgtat
    13081 caattttttt taaagggtag agacccaata agcagtttaa ctcattttat aggtgcttgt
    13141 ttatctcttt tagcaactat aattttagtt tttcaatctg ttacattaca ggaaacttct
    13201 ctcttgatga tagtatctgt atctgtattt ggactttcac taattgcttt atatagtgca
    13261 agttcgtatt atcatttttt aaaggggaca ccagaacaag aattgttttt tagaaaagta
    13321 gaccatgcaa tgatttacgt attgattgct ggctcttata caccaatatg tctgaatttt
    13381 atggaaaaaa aagaaggcat aatatttgtt acagcaatat ggatagttgc atttattggc
    13441 ataataataa aaatattttg gatggatgca cctagatggt tatctaccag tatatattta
    13501 cttatggggt gggcaattgt ttttgatata aatgcattca attcaattcc taaggattgc
    13561 cttagactat taattatgga aggtgtatct tactctatag gtgcgattat ttatataatt
    13621 aaaaagccta atataagtcc tgagtttgga tttcatgaaa tatttcatat ttttattatg
    13681 ataggttctt tatttcactt tttagcagtt ttattgtatg ttttatagtt ttaaaagatt
    13741 tgattaattg atactaaaat tctacaatga ataaaatgga actgccttat atagattata
    13801 tcttagacaa taagacagtt ccttattata aatattaaat tctacttata ataaaatttt
    13861 gataaaaata gtccattcaa aatgcctatt ccataattcc tttaatgtac ttttcattta
    13921 cgacatatag tttgaattta tgtactataa ttatatcctc taaattctct gaaacactaa
    13981 caattctgac acatttgttt ctaatttcta caggtaaatc taaatcattt gttaaattca
    14041 catagtcatc atatttatac ataaaatcat ccctttacat taagatatac ttattatact
    14101 atattttaat aagttttttt aaattattac aatttttccc gaaatttcat tttttataca
//
LOCUS       DAJMZY010000106        13950 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.107, whole genome shotgun sequence.
ACCESSION   DAJMZY010000106 DAJMZY010000000
VERSION     DAJMZY010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13950)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13950)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13950
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.107"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            complement(95..334)
                     /locus_tag="OE968_003047"
     CDS             complement(95..334)
                     /locus_tag="OE968_003047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCP7220307.1"
                     /translation="MNYNLIKVIFSLFKKKSGYTFTNFLNKVRVEKSKKYILKKDLSI
                     LDVAVLIGFNSQNYYSIIFKKFNNFTPIEYKNIYN"
     gene            605..796
                     /locus_tag="OE968_003048"
     CDS             605..796
                     /locus_tag="OE968_003048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220308.1"
                     /translation="MERLMELIERKFLKDVELLELEDIENVIECKMTQPYNAHYNEYL
                     VKVKNGDEVEEYFVYLKHR"
     gene            complement(885..1697)
                     /locus_tag="OE968_003049"
     CDS             complement(885..1697)
                     /locus_tag="OE968_003049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mrp/NBP35 family ATP-binding protein"
                     /protein_id="HCP7220309.1"
                     /translation="MADCNSCPSKGNCNSQSNCSIENNPNNKFGKIIGVMSGKGGVGK
                     STVTALLANKLNKMGYKVGILDSDITGPSIPRLMGVKNVKAYSDGSYIYPVENSNNIK
                     VMSINLMIDDENEPVVWRGPLLGGVVKQFYTDVLWEELDYLLIDMPPGTGDVALTVMQ
                     SIPISGIVMVSVPQDLVSMIVSKAVNMAKKMNINVLGVIENMSYIQCPDCSKKIKLFE
                     GESTEKFLDDLDLELLGELPMTKEIIDITHNGVTEISDDLDSILTNVVEKIK"
     gene            2119..3270
                     /locus_tag="OE968_003050"
     CDS             2119..3270
                     /locus_tag="OE968_003050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004452985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCP7220310.1"
                     /translation="MELRPRSAKLEEFDKVIELINYVFRISRNHKPTMMEEFPLLLSK
                     NNIENMIIISEDDKVVSDVNYLIQDVSIQGNRLKVAAIGGVCTHPDYEKRGYSSKILD
                     KVEEKMFYDGVDIVIISGTRSLYSRRNCSLVKSFYKYTIKPEDVKIAYEIVEFDETNF
                     EKDNDLDKMIELYNQNSTRFIRTRDEFQKLLHAATIAWGPIGYKKVFIKENNNIIGYL
                     IIRTIKKEDSTVGEVAEIGLNSVNVENILKYVANKFGLESLNYKVHVKNLKDQLKCNG
                     TKSLDYQQGTMKIINFTKLCDSLRSYFSQYVDFELLKYMEFKQVENKYIIKYKEEELV
                     IENLDKLNKLFFEKNEEQYNEFKHLKNIYEFATKAFPVDFPWTANLNYQ"
     gene            3388..4026
                     /locus_tag="OE968_003051"
     CDS             3388..4026
                     /locus_tag="OE968_003051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423639.1"
                     /note="Presence of a B(12) (cobalamin)-binding domain
                     implies dependence on cobalamin itself, in one of its
                     several forms, or in some unusual lineages, dependence on
                     a cobalamin-like analog; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin-dependent protein"
                     /protein_id="HCP7220311.1"
                     /translation="MDILDDIAECILNMGVDNIENLVKIAIDKNIDVEDIYEYGLNKG
                     MIGALDKFENKEYYLSEVIVCTDALNKGINLLKGTGKVKKKSKGVILMSVVEGDTHEI
                     GKNIVKVMVEATGYKVIDLGVNRKSEDIIEEAIKNNVDIIGLSSMMTTTMENMKSVID
                     ELNMIEIDKRPKVIIGGGPVSMEFAEEIGADGYSSNAPKAVKLINKLIGGEV"
     gene            4027..5049
                     /locus_tag="OE968_003052"
     CDS             4027..5049
                     /locus_tag="OE968_003052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase"
                     /protein_id="HCP7220312.1"
                     /translation="MFSDMTLLQYINSEDRGFFLPDMGTNGLFLINKKAYEVYDSVDL
                     QLELAKTMDKYFESDFIYSFCDGITFCETLGLDTLRPDYDFPSVLTHTITDRDKLRKL
                     DVPDPYTSGRMPLNIESLSVISKSIKKPLYESIQGPFTLAGQLAGATQLLRCIITDKK
                     FVEELLEFTTELVRRYAVAANKAGAKYISIAEPTSVTLSKDRFDEFIVKNLNKIYNEL
                     DCWKGMHICGDTRELLDNMLSCNIDAVSLDQILDYEEIAPMIPRDIVLIGNLDPIKLL
                     GRSKPDKIRRETLKLLKKMRRYDNFLCDFGCNCLNTTPVENLQAAIKAGRISYKELDR
                     IDIDEL"
     gene            5039..5659
                     /locus_tag="OE968_003053"
     CDS             5039..5659
                     /locus_tag="OE968_003053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220313.1"
                     /translation="MNYNSNKNKYLLKDINLDDIFIDKNIVLKFLGYGNRKAPDTISK
                     IVEREIRNINDILDIKIYISEVDINKTPKECKKAFAVLYTIGDKIDFKMNDYMENCNM
                     MAGLALDKVGIVCLDCINEKIKMYLKGKYDSLKISHEIYPGDKDFEVERQKDIYNYVK
                     NKYNSIEIEINDYHQLSPIKSVAMLILMGDEENLESRCSKCPRKCF"
     gene            complement(5783..6469)
                     /locus_tag="OE968_003054"
     CDS             complement(5783..6469)
                     /locus_tag="OE968_003054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HCP7220314.1"
                     /translation="MKTYKFIFFDADDTLFDFKKSESHAFKKLLSEFDLEFNFENYIE
                     SYRNISDKLWLDLEKNIITLNELKLLRFELFANKISLDVDSETLSKMYLNFLGECTFL
                     IPGAIDILQYLKKKYTIVIITNGISAVQKKRLENSKIKEYIDGMVVSEELKISKPNPE
                     IFKYALKKFNCHDKSSALIIGDSLTSDILGGINSGIDTCWLNSNNSINYTNHIPTYEI
                     NTLIELKKLL"
     gene            complement(6483..7028)
                     /locus_tag="OE968_003055"
     CDS             complement(6483..7028)
                     /locus_tag="OE968_003055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCP7220315.1"
                     /translation="MNDLNLGEKIAEVRKKQNLSIRDLAKLADVTPSLLSQIERGLAN
                     PSVNSLKSIASSLNVPLFTFFVSEVDKKNLIVRHDNRKKVILPGSKEVIYEILIPDSS
                     GNLEFAIMDLAPNTSSCVDRITHNGDEIAYVLEGEVKLFMDDDEFTLSKGDSVKVPLG
                     TKHKWQNDSNSESKVIFAVIL"
     gene            7256..8503
                     /locus_tag="OE968_003056"
     CDS             7256..8503
                     /locus_tag="OE968_003056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HCP7220316.1"
                     /translation="MQITTFGAIFGLLIAIILIIKKFQAVYSLMLGAFIGGLVGGANI
                     TQTVDFMANGAMNISPSILRALASGVLAGSLIKTGAVDKISEQIVKIFGEKRALFSIA
                     ISTMVLAGVGVNLDVSIITVAPIGLYIGRKLNYSKLSILLAMLGGGKAGNIISPNPNT
                     IAVADNFSVNLSSVMMANIIPAIIGVVITVILASILINKGNKVQSYEILEQREDLPSL
                     FKSLCGPIIAIFLLFLGNVSPIVIDPMIALPIGGIVTLIVTGNLNNSREYLAFGLSKM
                     QGVCILLLGTGTIAGIIQMSELQQSTIGALQFLNMPQFLLAPVSGILMSLATASSTAG
                     ATIASSTFHDAIINGGLSPISGASIVNAGSSVFEQLPHGSLFHTSAGSINMDIGERFK
                     LIPYEALIGIVMTIISTSIQLVL"
     gene            8590..10584
                     /locus_tag="OE968_003057"
     CDS             8590..10584
                     /locus_tag="OE968_003057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HCP7220317.1"
                     /translation="MNKKKIVIIGIIYSFLVVFSLTNMYVNMEYNLNVFEYIKKSLPF
                     TEEEKKWLEKHKNLIYSSDQSSPPLRYKGKEDGQYKGIIVDLINSLSIQIGRDFYFKP
                     NNWWKESFVNSIDDSIKFFDLIPSKERANKFIFTDPIYTLSANILKDKKSQDINSYMD
                     LKGKTVAIPEGDYSINFLKQKIQDINILLTPDIKTGVNHLMSGKVDAVVGDEPVLRYY
                     INNYGLSNKYSVLSNPIYTKKAVLAVPKQYEELVSILNKGIFKLQKNGVYKDLKKKWY
                     STYNEVDDILYERGIVPSIYLFIGIILISIYVFYSYTYLLKIEIKRKTEQVIENKKTL
                     EATFNSITDIIMLVDENNNIVESNKVLYDFMGEMSYKIADLISMIKGVIENTFSENTN
                     KTSEIEIHNKILKINTFPVEYKKNNTEYIVVLIKDITNDKIVEAKLLRENKMISIGQL
                     ASGVAHEIRNPLGIIRNNCYLLKDNVTMEEVNDCVKSIESNVDRASNIITNLLNFARI
                     SDDNLEHINIRNFIENIVKLQYKMLQLKNVEIKIDCEHNLVCYINGESLKHVFINLIS
                     NSIDAIHQDGKIIIYCYEKNYCLFIDFKDNGEGIKEDALKDIFNPFYTTKPIGEGTGL
                     GLYITYNEIKKNNGDISVESKLGVGTCFHIKIPLNKEVTI"
     gene            10584..11906
                     /locus_tag="OE968_003058"
     CDS             10584..11906
                     /locus_tag="OE968_003058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54-dependent Fis family transcriptional
                     regulator"
                     /protein_id="HCP7220318.1"
                     /translation="MKILLVDDELEYGVVMKKILQKKGYLVDIALSGEEAINIIKKDK
                     NYDLVLSDVMMKNMDGVQLLDRIKSINRDIEVILVTGYGSIENAVDAMKRGALSYFIK
                     SNPIENLLEEVEKVKASKISVSVQKNNLEFTLESKNRDFNNIIKIAKKAACKDVNILI
                     LGESGVGKDILARYIHSISPRKNEIFVPVNCCSFSENLLESELFGHEKGSFTGAVDSR
                     KGRFELSNKGTLFLDEIGDIPLNVQVKLLRTLEDKSIERIGSNKSIKVDFRLICAMNK
                     EPKVEISNGNIREDFFYRISTITITIPPLRKRREDLTTLIEFFLNKYQIEHDKKIHSI
                     DKEVKDFLLNYNYPGNIRELKNIINRLVVLSEEGNLSKDNLNLISNNVYIDDKISIRP
                     LREIRKEFECEYIEKVLSLCGNNISNTAKKLEISRRQLTNKISEYNIK"
     gene            12185..13471
                     /locus_tag="OE968_003059"
     CDS             12185..13471
                     /locus_tag="OE968_003059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006807454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine/sarcosine/betaine reductase component B
                     subunit"
                     /protein_id="HCP7220319.1"
                     /translation="MKLELGNIFIKNVEFGEKTEVKDGVLYISSEEIEKIVLEDERIV
                     SVNVELARPGESIRIAPVKDVIEPRVKIGDESKIFPGIINKVKTVGSGRTHVLLGACV
                     VTCGNIVGFQEGVIDMSGPTAKYTPFSKTNNICIVIKAKDGIDTHDYEEAARIAGLKI
                     GAYVGEAGREVEPDEVIVYETKPLLKQVKEYPDLPTVAYVHMLQSQGLLHDTYYYGVD
                     AKQIVPTFMYPTEIMDGAIISGNCVAPCDKVTTFHHLNNPVIHDLYKRHGKDLNFIGV
                     ILTNENVFLVDKERSSDMVAKLIEFLGVDGVLVTEEGYGNPDTDLMMNCRKCSEVGAN
                     VVLITDEFPGKDGKSQSIADATKEADAVVSCGQGNLVVHFPAMEKIIGTLDYVEMMIG
                     GYKGCLNEDGSMDAELQIIIASTIANGYNHLTARYY"
     gene            13557..>13950
                     /locus_tag="OE968_003060"
     CDS             13557..>13950
                     /locus_tag="OE968_003060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006316653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine/betaine/sarcosine/D-proline family
                     reductase selenoprotein B"
                     /protein_id="HCP7220320.1"
                     /translation="MSKIRVVHYINNFFAGIGGEEKADIPPEKRAGVVGPGIAFQSQF
                     NDDAEIISTVICGDTYFGENIESATQELLKMIKEESPDLFIAGPAFNAGRYGVACGTI
                     CKAVEEELNIPVITGMYKENPGVDMFKLD"
BASE COUNT         5559 a         1452 c         2304 g         4635 t
ORIGIN      
        1 tttttagtat tttatgtaca aacaatttaa caaagaatta actataattg taaaaaatat
       61 gtaaaaaaat aacatccttt tagaatgata ttttttagtt ataaatattt ttatattcaa
      121 ttggtgtaaa gttattaaac tttttaaaaa ttatactata gtaattttga ctattgaatc
      181 caattagtac agcaacgtct aaaatagaca agtctttttt taatatatac tttttgcttt
      241 tttcaactct aactttattt aaaaaattag taaaagtata tccacttttt ttcttaaaca
      301 aagaaaaaat aacttttatt aagttgtaat tcattacata tattacttac tgttatatct
      361 tctgagtaat ttttgtgaat ataatttata gttttcttta agttttcttt acataaaact
      421 aagagttggt ctatgtttca ttttatcaag gcatatttat taaaaaatca atctctattt
      481 gttaaaataa tttatgaatg atgttagaaa ctgtaatata ttggatataa tataataaac
      541 agataaactc tgcattaaga ggatatatag tttatcttaa ttatagggga agtgaggata
      601 tattatggaa agattaatgg aactcataga aagaaaattt ttaaaggatg tagaactttt
      661 agaattagaa gacatagaaa atgtaataga atgcaaaatg acacagccat ataatgctca
      721 ttataatgaa tatttagtaa aagtaaaaaa tggagatgaa gtagaagaat attttgtgta
      781 tttaaaacat agataaacat aaaagaggtt tatatttatt tgtatgatta taaaataaat
      841 acaagcctct ttttttgata aatataaaat tataaaattt ttatttattt aattttttca
      901 acaacattag tcaatattga atctaaatca tcactaattt ctgtaactcc attatgagta
      961 atatctataa tttctttagt cataggaagt tctcctaaaa gctctaagtc taaatcatct
     1021 aaaaactttt cagtagattc tccttcaaat aacttgattt ttttagaaca atcaggacat
     1081 tggatataac tcatattttc aataactcca aggacattta tgttcatttt tttagccata
     1141 ttaacagctt ttgatacaat catagatacc aaatcttgag gtactgaaac cataactatt
     1201 ccacttatag gaatagattg cataactgtt aaggcaacat ctccagtacc aggaggcata
     1261 tctattaata aatagtctaa ttcttcccaa agtacatcag tataaaattg ctttacaacc
     1321 cctccaagta aaggtcctct ccaaacaaca ggttcatttt catcatctat cataaggttt
     1381 atagacatta cttttatgtt atttgagttt tctacagggt aaatataaga gccatcagaa
     1441 taagctttta cattttttac acccataagt ctaggaatac ttggtccagt tatatctgag
     1501 tctaatatac caaccttata tcccattttg tttagcttat tagcaagtaa agcagttaca
     1561 gttgattttc caactccacc cttcccactc ataacaccaa ttatttttcc aaatttattg
     1621 ttagggttat tttcaataga acaatttgat tgactattac aatttccctt tgatggacat
     1681 gaattacaat ctgccatatc tattacctcc aaactttaat atttattaga ttatttgtaa
     1741 cctacatata ctattttagt acaattgaac cataaagtca ttatttaaaa gcaacttaga
     1801 agattttcta ttgatttatt catagactat agcaaaaaga atacaataaa aaaattataa
     1861 cattcttgaa aaagtgatta tttcaattta gttatagaac ttagtcatat aaatatatag
     1921 aaaatatttt aatatattat acataacggg ttattttata agtttaacta taaattaggt
     1981 ttatatttta taaaaatttg ctaaaaaaaa caattaaaaa ttgtaaagaa aaaagatata
     2041 attagaactg tagtaataaa tgttttatta tagataatag agttttaagt atcttaaata
     2101 atatttggag gaatatgaat ggaattaaga ccaagaagtg caaaattaga agaatttgat
     2161 aaagtaatag aattaataaa ctatgtattt agaatatcaa gaaatcataa accaactatg
     2221 atggaagaat ttcctctttt actaagtaaa aataatatag aaaatatgat tataatatca
     2281 gaagatgata aagtggtttc tgatgtaaac tatctaattc aggatgtatc tattcaagga
     2341 aacagattga aggttgcagc tataggtgga gtatgtactc atccagatta tgaaaagaga
     2401 ggctattcat ctaagatatt ggataaagta gaagaaaaaa tgttttatga tggtgtagat
     2461 attgtaatta tatcaggaac aagaagtcta tacagtagaa gaaattgtag tttggtaaag
     2521 agtttttata aatatacaat aaaacctgaa gatgtaaaaa tagcatatga aatagttgaa
     2581 tttgatgaaa ctaattttga aaaagataat gatttagata aaatgattga actatataat
     2641 caaaatagta ctagatttat aagaacgaga gatgagtttc aaaaactatt gcatgcagca
     2701 actattgcct ggggaccaat tggttacaag aaggtattta taaaggaaaa taataatata
     2761 ataggatatt tgataataag aacaataaaa aaagaagatt ctactgtagg agaagttgct
     2821 gaaatagggt taaactctgt aaatgttgaa aatatattga aatatgttgc aaataaattt
     2881 ggattagaat ctttaaatta taaagtacat gtgaaaaatc ttaaagacca gttgaaatgt
     2941 aatgggacaa aatctttgga ttatcaacaa ggaactatga aaataataaa ttttactaag
     3001 ttgtgtgata gtttaagaag ttattttagt caatatgtag attttgaatt actaaaatac
     3061 atggaattta aacaagttga aaataaatat attattaaat acaaagaaga agaacttgta
     3121 atagaaaatt tggataagct taataaactg ttttttgaaa aaaatgagga acagtacaat
     3181 gaatttaaac atctaaaaaa tatatatgaa tttgctacaa aggcatttcc tgtagatttt
     3241 ccatggactg caaatttaaa ttatcaatag ttttagatga tattaaataa aattgattga
     3301 tacctagagt tagtccttgt taaataagag aaattattgg atattgaaaa agcaattttg
     3361 taagtaatta gaaaggatga gtattatatg gacatacttg atgatatagc agaatgtata
     3421 ttaaatatgg gtgtagataa tatagagaat ttagtaaaaa ttgctataga taaaaatatt
     3481 gatgtggaag atatttatga atatggttta aacaaaggta tgataggagc tttagataag
     3541 tttgagaata aggaatacta tctttcagaa gttatagtat gcacagatgc attaaataaa
     3601 ggtattaatc ttttgaaggg aactggaaaa gtaaagaaaa aatcaaaggg agtaattctg
     3661 atgtctgtag tagaaggaga tactcatgag ataggaaaaa atattgtaaa agtaatggta
     3721 gaagccactg gatataaggt tattgactta ggtgtaaata gaaaaagtga agatataata
     3781 gaagaagcta taaaaaacaa tgtagatata ataggcttat cttcaatgat gacaactaca
     3841 atggaaaata tgaaatcggt tatagacgaa cttaatatga ttgagataga taaaagacca
     3901 aaagtaataa ttggtggagg acctgtaagt atggagtttg cagaagaaat aggagcagat
     3961 ggatacagtt caaatgctcc aaaagcagtt aaattaataa ataaacttat aggaggtgaa
     4021 gtttaaatgt tttcagatat gactttactt cagtatataa atagtgaaga tagaggtttt
     4081 tttctgcctg atatgggtac aaatggattg ttcttaataa ataaaaaggc atatgaagta
     4141 tatgatagtg tagatttgca attagaatta gcaaagacta tggacaagta ttttgaatca
     4201 gattttatat actcattctg tgatgggatt acattttgtg aaactctggg tttagataca
     4261 ttaagaccag attatgattt tccaagtgta ttgacacata ctataactga cagagataaa
     4321 ttaagaaaat tagatgttcc agacccttat acgagtggac gtatgccact caatatagag
     4381 agcttatcag ttatatcaaa aagtattaaa aaaccactat atgaatcgat acaaggtcca
     4441 tttacacttg caggtcaatt agctggagct actcaacttt taagatgtat aataactgat
     4501 aaaaaatttg tagaagaatt attggaattt acaactgaat tggtaagaag atatgctgta
     4561 gctgcaaata aagcaggagc aaaatatatt tcaatagcag agccaacatc agtaacccta
     4621 agtaaagata gatttgatga atttatagta aaaaatttaa ataaaatcta caatgaactt
     4681 gattgttgga aaggtatgca tatatgtgga gacaccagag aattattaga taatatgcta
     4741 agttgtaata tagatgcagt aagtttagac caaattttag actatgaaga aattgctcca
     4801 atgattccta gagatatagt tttgattggt aatttagacc caataaaact tcttggacgt
     4861 tctaagccag ataagattag aagagagaca ctaaaattgt taaagaagat gagaagatat
     4921 gataactttt tatgtgattt tggctgtaac tgcttaaata ccactccagt agaaaattta
     4981 caagcagcta taaaggcagg aagaattagt tataaagaat tagataggat tgatattgat
     5041 gaattataat agtaataaaa ataaatatct tttaaaggat ataaatttag atgatatttt
     5101 tatagataag aatattgtgc taaagttttt ggggtatgga aatagaaaag ctccagatac
     5161 aattagtaaa atcgttgaaa gagaaataag aaatataaat gatattttag atatcaagat
     5221 atatataagt gaagttgata ttaataaaac acctaaagaa tgtaaaaaag catttgctgt
     5281 actatataca ataggggata aaattgattt taagatgaat gactatatgg aaaattgcaa
     5341 tatgatggca gggctggcat tggataaggt aggtatagta tgtttagatt gtattaatga
     5401 gaaaataaaa atgtatttaa aaggaaagta tgatagtctc aaaatatcgc atgaaatata
     5461 tccaggagat aaagattttg aagtagagag acaaaaggat atttataact atgtaaaaaa
     5521 taaatataat agtatagaaa tagaaattaa tgattatcat caactatccc ccataaaaag
     5581 tgttgcaatg cttattttaa tgggggatga agaaaattta gaatcaagat gtagtaagtg
     5641 tcctagaaaa tgcttttagt taattttcaa gactaagatt tgttttgtgt ataaattgca
     5701 ataatttttt tggtcatttt atgtataaac taaaaaaatt attgcaaagt aatattctat
     5761 ttaatttgaa cagacttaca aactatagta gtttctttaa ttcaataagt gtatttattt
     5821 cataagttgg tatatgatta gtataattta tactgttatt ggaatttaac caacaagtat
     5881 ctattcctga atttattcca cctaagatat cagaggttaa gctatcccca attattaagg
     5941 cagaagattt atcatgacaa ttaaactttt tgagagcgta tttaaatatt tcaggatttg
     6001 gttttgatat tttcaactct tcagatacaa ccattccatc aatatattct tttatttttg
     6061 aattttcaag tcttttcttt tgaactgcag aaattccatt tgttattata acaatagtat
     6121 actttttttt aagatattgt aatatatcga ttgcacctgg aattaaaaat gtacattcac
     6181 ctaaaaaatt taagtacatt ttgctaagag tttcagaatc aacatccaaa gatattttat
     6241 ttgcaaaaag ttcaaatcta agtaatttaa gttcattcaa agttataata tttttttcaa
     6301 ggtcgagcca aagcttatca cttatatttc tatatgactc tatataattc tcaaaattaa
     6361 attctaaatc aaactcagat agaagttttt taaaagcatg tgattcactt ttcttaaaat
     6421 caaataaagt atcatctgca tcaaaaaata taaatttata tgtcttcatg gtttttactc
     6481 ctttacaaga tgactgcaaa aattacttta ctttcactat ttgagtcatt ttgccattta
     6541 tgttttgttc ctaaaggaac ttttacacta tctcctttgg acaaagtaaa ttcatcatca
     6601 tccataaaaa gtttaacttc tccctccaaa acatatgcaa tttcatctcc attatgagta
     6661 atcctatcaa cacaagaaga agtgtttgga gctaaatcca taattgcaaa ttctaaatta
     6721 ccactagagt ctggaattaa aatctcatat ataacttctt tgcttccagg taaaataact
     6781 ttttttctat tatcatgtct tactatcaag ttttttttat ctacctcaga tacaaaaaat
     6841 gtaaataaag gaacgtttag agaagaggct atagatttta atgaatttac agatggatta
     6901 gcaagacctc gttctatttg gctcaataat gatggtgtaa catcagctag ttttgctaaa
     6961 tctcgaatac ttaagttttg tttttttcga acttcagcta ttttttcccc taaatttaaa
     7021 tcattcatat aaatatcctc tctttttaat ttaaaaaata ttaacttaaa ataatcaagt
     7081 aaaatgatta tgtagtatga aattattata acatatagaa ttaggttttg aaaaaactat
     7141 gttcaatata attaaataaa ttaaaatata attgacaaag tggatacaga atacttaaaa
     7201 tatatttaaa taaaattaag caaaagatag ttaatttatg ataggagggg atattatgca
     7261 aataacgact tttggagcta tatttggttt attaatagca attattttaa ttataaaaaa
     7321 atttcaagct gtatatagtt taatgctagg agcatttatt ggaggattag ttggaggagc
     7381 aaatataaca caaactgtag attttatggc aaatggagct atgaatatat caccatcaat
     7441 tcttagagct ttggcatcag gtgtattagc tggaagttta ataaaaacag gggcagtaga
     7501 taaaatatca gaacagattg taaaaatatt tggtgaaaag agggctttat tttcgattgc
     7561 catttcaact atggtacttg ctggagtagg cgtaaatttg gatgtatcta taataactgt
     7621 agcacctata ggattatata taggtagaaa attaaattat tctaaattgt caatactatt
     7681 agctatgttg ggagggggta aagcaggtaa tataatatca ccaaatccaa atactatagc
     7741 agtagcagat aatttttctg tcaatctctc tagtgttatg atggcaaata taattccagc
     7801 aattattgga gttgttatta cagttatttt agcaagtata ttaataaata aaggaaataa
     7861 agtacaatca tatgaaattt tagagcaaag agaagattta ccaagtttat ttaaatcatt
     7921 atgtggtcca attatagcta tatttctatt gtttttagga aatgtatctc ctatagttat
     7981 agacccaatg atagcccttc caataggagg aatcgtaact ctaattgtca caggaaactt
     8041 gaacaattca agagaatatt tagcttttgg attatctaag atgcaagggg tatgcatatt
     8101 attacttgga acagggacta tcgcaggaat tatacagatg tctgaattac aacagagtac
     8161 aataggtgct ttacaatttt taaatatgcc acaattttta ttggcaccag tttcgggtat
     8221 acttatgtca ttagcaacag catcatcaac agctggtgct actatagcat catctacttt
     8281 tcatgatgct ataataaatg gtgggctatc accgatttca ggtgcctcaa tagtaaatgc
     8341 tgggtctagt gtattcgagc aattaccaca tggctcacta tttcatacta gtgcaggtag
     8401 tataaacatg gatataggtg aaagatttaa gttaattcca tatgaagcat tgataggaat
     8461 agtaatgact ataatttcaa catctattca attagtttta taataaatat aaatatttaa
     8521 tgaaaaaagt aggattttgt tattaaatat tgaatttatt atagtaaaaa agaagattgg
     8581 agttttaaag tgaataaaaa aaagattgtt attataggga ttatttattc atttttagta
     8641 gtattttcac ttacaaatat gtatgtaaat atggagtata atctaaatgt atttgaatat
     8701 attaagaagt cacttccatt tacagaagaa gaaaaaaagt ggttagaaaa acacaagaat
     8761 ttgatttaca gctctgacca aagttcacct cctttgagat ataaaggtaa ggaagatgga
     8821 cagtataagg gaattattgt tgatttaata aattctctgt caattcaaat tggtagagat
     8881 ttttatttta aaccaaataa ttggtggaaa gaatctttcg taaattcaat agatgatagt
     8941 ataaagtttt ttgacttgat tccatcaaaa gaaagggcaa ataaatttat atttactgac
     9001 ccaatataca ctttgagtgc aaatatattg aaagataaaa agtcccaaga tataaatagt
     9061 tacatggatt taaaggggaa aacagtagca attccagaag gtgattattc tataaatttt
     9121 ttaaagcaaa aaattcaaga tataaacatt ttgttgactc cagatataaa gactggagtc
     9181 aaccatttaa tgtctggaaa agtagacgca gttgttggtg atgaaccagt attgcgatac
     9241 tatataaata attatggact ttcaaataaa tacagtgttt taagtaatcc tatatatact
     9301 aaaaaagcag ttcttgctgt acctaaacaa tatgaagagc tggttagtat tttaaataaa
     9361 ggcattttta aacttcagaa aaatggagtg tataaagatt taaagaaaaa atggtattct
     9421 acgtataatg aagttgatga tatattgtat gagcgaggaa ttgtgcctag tatttatctt
     9481 tttataggta taattttaat atcaatttat gttttttata gctatacata tttgttaaag
     9541 atagaaatca aaaggaaaac agaacaggta atagaaaata aaaaaacttt agaggcaact
     9601 tttaatagta ttacagatat aataatgctt gtagatgaaa ataacaatat agtagaatcg
     9661 aacaaagtac tatatgactt tatgggtgaa atgagttata agatagcaga tttgattagc
     9721 atgataaaag gtgttattga aaataccttc tctgaaaata ctaataaaac tagtgaaata
     9781 gaaatacaca ataaaatttt aaagataaac acttttcctg tagagtataa aaaaaataat
     9841 actgagtata tagtagttct tattaaagat ataactaatg ataaaatagt agaggcgaaa
     9901 ttacttagag aaaacaaaat gatatctata ggacaattag cttctggggt agcacatgag
     9961 ataagaaatc ctttgggtat aataagaaat aattgctatc tcttaaaaga taacgttaca
    10021 atggaagaag taaatgattg tgttaaatca atagaaagta atgtagatag ggcaagtaat
    10081 ataataacca acttgttaaa tttcgcaaga atatcagatg ataatttaga acatataaat
    10141 ataagaaatt ttattgaaaa tatagtgaaa cttcaatata aaatgttaca gttaaagaat
    10201 gttgaaataa aaattgactg tgaacataat ttagtatgct atataaatgg agaatcgtta
    10261 aaacatgtat ttataaattt aatttctaat tcaatagatg caatacatca agatggaaaa
    10321 attattatat actgttatga aaaaaattat tgtttattta tagattttaa agataatggt
    10381 gaaggaataa aagaagatgc cctaaaggac atatttaatc ccttctatac aacaaaacca
    10441 attggtgagg gaactggttt aggtttatac attacttata atgagattaa aaagaataat
    10501 ggagatataa gtgttgaaag taaattgggg gttggaactt gttttcatat aaaaattcca
    10561 ttaaataaag aggtgactat ataatgaaaa tactattagt tgatgatgag ctagaatatg
    10621 gagtggtaat gaaaaaaatt ctacaaaaga agggctatct tgtagatata gcactaagtg
    10681 gtgaagaagc tataaatata attaaaaaag ataaaaatta tgatttggtt ttgtctgatg
    10741 ttatgatgaa aaatatggat ggagtacagc tattagatag aattaaatct attaatagag
    10801 atatagaggt tatattagtt acaggatatg gaagtattga aaatgcagtt gatgctatga
    10861 aaagaggagc tttatcttat tttataaaaa gtaatcccat tgaaaattta ttagaagaag
    10921 ttgaaaaggt aaaggcaagt aaaatatctg tttctgtaca aaaaaataat ctggaattta
    10981 ctttggaatc taaaaataga gattttaata atatcataaa aatagcaaaa aaagctgctt
    11041 gtaaagatgt taatatatta atcttggggg aatctggtgt aggaaaagat atattagcta
    11101 gatatataca tagcataagt ccaagaaaga atgagatatt tgtacctgta aattgttgtt
    11161 ctttttcaga aaatctattg gagtctgagt tgtttggtca tgaaaaaggt tcttttacag
    11221 gagcagtaga tagtagaaaa ggtagatttg aactttcgaa taaaggaact ctatttttgg
    11281 atgaaatagg agatatacct ctaaatgttc aggtaaaact tttgaggaca cttgaggaca
    11341 aatctataga gaggatagga agtaataaat ctattaaagt tgactttagg ttaatttgtg
    11401 ctatgaataa agaaccaaaa gtggaaatat caaatggaaa tataagagaa gatttttttt
    11461 atagaataag tacaataaca ataactatac caccgctaag aaagagaaga gaagacttaa
    11521 ctactcttat agaatttttc ttaaataagt accaaattga acatgataaa aagatacact
    11581 cgattgataa ggaagtaaag gattttttat taaattacaa ttatccagga aatataagag
    11641 aattaaaaaa tataataaat agacttgtag ttttaagtga agaaggcaat ttatcaaaag
    11701 acaatttaaa tttaatatca aataatgtat acatagatga taaaataagt attagacctt
    11761 taagagaaat aagaaaagag tttgaatgtg agtatattga aaaagtttta tctttgtgtg
    11821 gaaataatat ttcaaataca gctaaaaaat tggagattag tagaagacag ttaaccaata
    11881 aaatatcaga gtataatatt aagtgagaaa aaaacttctc attaagtgag aaaaaaattt
    11941 ctcaaactgt attaaaagat aaacagaaaa aatctgttta tcttttttta ttataatttt
    12001 aaaaattaat atttacaata attattgcta aattcaatat tggtgtaaat taaaaatgaa
    12061 aatttctatg acattaatac atagaatata tattttaaat aattggcata gaaaatgctt
    12121 tatatattaa taaacgtaat aaatactttt aattgcgatt aaatatatta agggggattt
    12181 tcatatgaag ctagagctag ggaatatatt tataaaaaat gttgaatttg gagaaaagac
    12241 agaagtaaaa gatggagtac tatatattag tagcgaagaa atagaaaaga tagtattaga
    12301 agatgaaagg attgtaagtg taaatgttga acttgcaaga cctggcgaat caataagaat
    12361 agctccagtt aaagatgtaa tagagcctag agttaaaatt ggagatgaaa gcaaaatatt
    12421 tcctggaatt ataaataaag tgaagactgt aggaagtgga agaacccatg tacttttagg
    12481 agcttgtgtt gtaacttgtg gaaatatagt tggatttcaa gaaggcgtaa ttgatatgag
    12541 tggtcctact gctaaatata cacctttttc aaaaacaaat aatatatgta ttgttataaa
    12601 agcaaaggat ggtatagata ctcatgatta tgaagaagca gctagaattg caggattaaa
    12661 aataggtgca tatgtaggtg aggcaggaag agaagttgag ccagatgaag tcattgtata
    12721 tgagacaaag ccattattaa aacaagtaaa agaatatcca gacctgccaa cagtagcata
    12781 tgttcacatg ttacaatcac aaggactttt acatgacact tattactatg gggtggatgc
    12841 taaacagata gtgcctacat ttatgtatcc aactgaaata atggatggag ctataatatc
    12901 tggaaactgt gtagcaccat gtgataaggt tacaacattc catcatttaa ataatccagt
    12961 tatacatgac ttatataaaa gacatggaaa agatttaaac tttataggag ttattttgac
    13021 taatgagaac gtattcttag tcgataaaga gagaagctct gatatggtag ctaaattaat
    13081 agaattttta ggagttgatg gagttctagt gacagaagaa ggttatggga atccagatac
    13141 tgacctaatg atgaattgta gaaaatgtag tgaagttgga gcaaatgtag ttttgataac
    13201 ggatgaattt cctggaaaag atggcaagag tcaatctata gcagacgcta ctaaggaagc
    13261 agatgcagtt gtttcttgtg gtcaaggaaa tctagtggtt catttcccag caatggaaaa
    13321 aattatagga actttagatt atgttgaaat gatgataggt gggtataaag gatgcttaaa
    13381 tgaagacgga agcatggatg cagagctaca aattataata gcatcaacta tagcaaatgg
    13441 ctataatcat ttgacagcaa gatattatta aataagtatt tgaatataaa gttctgttga
    13501 tataatcatt ggtctaattg atgtaacaac tataaagtga tttggaggat taagagatga
    13561 gtaaaatcag agtggttcat tatataaaca atttctttgc tggtataggt ggagaggaaa
    13621 aagcagatat tccgccagaa aaaagggctg gtgtagtagg acctggaata gcatttcaga
    13681 gtcaatttaa tgatgatgca gagataatct caactgtaat ttgcggagat acgtattttg
    13741 gtgaaaatat tgagagtgca actcaagaac ttttaaaaat gataaaagaa gaaagccctg
    13801 atttatttat tgcaggccca gcatttaatg caggtagata tggagtagct tgtgggacta
    13861 tttgtaaggc agttgaagaa gagttaaata ttcctgtaat tacaggcatg tataaagaaa
    13921 atccaggtgt agatatgttt aaattagatt
//
LOCUS       DAJMZY010000107        13740 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.108, whole genome shotgun sequence.
ACCESSION   DAJMZY010000107 DAJMZY010000000
VERSION     DAJMZY010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13740)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13740)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13740
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.108"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            <1..167
                     /locus_tag="OE968_003061"
     CDS             <1..167
                     /locus_tag="OE968_003061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF2140 domain-containing protein"
                     /protein_id="HCP7220321.1"
                     /translation="LKNISIKKGNVDLDMEVEIDLKSQINGALGYLKDSGKVQDILNH
                     LINLKKTSVG"
     gene            326..889
                     /locus_tag="OE968_003062"
     CDS             326..889
                     /locus_tag="OE968_003062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220322.1"
                     /translation="MNKVYIVTTYTGTILSYLIRNISKKLYTHVSISLNENLKPMYSF
                     GRLNPRNPFIGGFVEENINQGLYAIRKNTVCRVYSLEVDNLQYENLYKNIKLISDYRE
                     DYYYDTMALIYLLMNIQRQSEYKYVCSNFVADMLEKSEIDILNKQAFEVTPNDFYNLS
                     GLTLEYEGLLSEYNSRQHSYVSKIANI"
     gene            1286..2986
                     /locus_tag="OE968_003063"
     CDS             1286..2986
                     /locus_tag="OE968_003063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220323.1"
                     /translation="MKRYLKTYGVALIIVIIYAFIKLPVLRLDFTSLFSVGIIFFVVA
                     GILDMMLDRNERASKMAKYNFSIAIALLVYIVVVPFITSTPVLHAKSYRELLGKVTES
                     KFTDDISPVSVNDIRLVDEDMAMKLGDKKLGEVPAIGSVSKLGKFHIQNVDGELYWVA
                     PLVHRDIIKWITSLSGTSGYVKVSASNPQDVQLVQEIDGKPIKIVYQPEAYLHQDLQR
                     HLYIHGIVNVGMTDFTLEINDEGRPYWVVSLYEHKIGYGGANATGIATVDAETGKINV
                     YDVKNTPKWVDRIQPQSFVTDQIKDWGVYVNGFLNSVISEKGVLVPTEGTSLVYGNDN
                     RSYWYTGITSSGGDESTIGFMLVDSRTKEARLYKQPGATETAAMKSAEGNVQEKNYEA
                     TFPVMYNILGQPTYVSSLKDKAGLVKRVAFVSVEDYNVLGIGEDKNEALRNYKDALES
                     KGNDLKLDNDLKDEVLEGTVTRISPDVRGGNTNYYVTLDSNKDIIFRATSKVSSELPL
                     TQVGDKVKISYSKEESGVIEMSEFDNLNIANFEDKKAKEKTGTDENTDSKDSENQGNV
                     "
     gene            3156..3773
                     /locus_tag="OE968_003064"
     CDS             3156..3773
                     /locus_tag="OE968_003064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220324.1"
                     /translation="MTNMEKEILLLISRVRCVTESQFRKIYGDQKRYNKKNFKKTLRK
                     MCSEYTLKKYPCDVDYYNYKDLSYVYYLNGSKLFKGDDLIKALVGSELVVRINTAGCD
                     VKRFYRNVSVDDVKYDLFIEYTDQFGNIKQVLVDVDLNNEIDISKYENLSKKIDKSTI
                     PFFKVPNVLVVTPDNLSELNDLERYDNEYSINFIDLGLNKLFNCI"
     gene            4134..5327
                     /locus_tag="OE968_003065"
     CDS             4134..5327
                     /locus_tag="OE968_003065"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HCP7220325.1"
                     /translation="MSIIVQKYGGSSVADTEKIKSIAENIIERRKENPQMVIVVSAMG
                     KSTDEYITLAKELSNEPSKRELDALMSTGEMISASLLSIALNALGCKAISYNAYQLNI
                     KTSGLHGKSQIDDINVNRIKNSLDEGNVVIVTGFQGINEDGDVTTLGRGGSDTSAVAL
                     AVKLNGKCEIYTDVDGIYFTDPRKYSKASKLDEIEYEEMLELASLGAQVMHSRSIELA
                     QKYGVEIYVGRTCGTEKGTYIRGGKDMKLEDKVITGLATSDDDSSITIKDFKAENISS
                     LFEDIATIGISVDMISQTAPILDKISVSFTVPKEELGECKKIVSKYTDEEHVVIDNNI
                     TKFSLVGLGMKNTSGVAAKVFKIFNENGIMIKLITTSEIRITCAINSDDKQVAIEKIA
                     EVFNI"
     gene            5345..6637
                     /gene="lysA"
                     /locus_tag="OE968_003066"
     CDS             5345..6637
                     /gene="lysA"
                     /locus_tag="OE968_003066"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HCP7220326.1"
                     /translation="MKLHGTMTVNNDELYIGGVSCLELSKKYQTPLYVFDEALVRQNC
                     REYVEYFKAREGKNKVAYAGKAFLPLYMCNLINEEQMCLDVVSGGELYTAYKSNFPME
                     KVFFHGNNKTKEEINMGLDLGVGKFVVDNFYELDLLEALCEDKGKTQEIYFRITPGIE
                     AHTHDYIKTGQIDSKFGFALVNGDLFRAIEKLSEYKNIKLVGLHAHIGSQIFDVEPYI
                     DTVDIMMNLVKEIKEKFNIQLTEIDLGGGVGVYYSEGDKPKTIKEFCETIITKAETSC
                     KELGIEVPTLVIEPGRSIVANAGSTLYTVGSIKDIKDVRVYVSVDGGMTDNVRPSLYQ
                     ASYECSIVNKINHEAMNHVTIAGKCCESGDILIGDINIMDIKSGDILITTSTGAYGYS
                     MSSNYNKIPRAAVVSVFDGNDKIICKRQSYEDLLALEI"
     gene            6854..7513
                     /locus_tag="OE968_003067"
     CDS             6854..7513
                     /locus_tag="OE968_003067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220327.1"
                     /translation="MRGRVILLISILSIFLVGCSFNKKDEINLVEQGKTYLEKHNYKK
                     AMESLSSALEEDSTNENARAMYMQAMRMSNMTEFEELKNYEGAIKELKLIEKIKNGSS
                     VIKEEATKKKEELTKLEKEQNEAEEQRKKKAKDTAGEDRYRVESDARKSSYSGSSKNN
                     KSSSKNNDKKSDSNKSDNSNSSSQNQEKPNNSNPTPAPTPQDTTGGSDSGGNSQNSNN
                     Q"
     gene            complement(7668..8753)
                     /locus_tag="OE968_003068"
     CDS             complement(7668..8753)
                     /locus_tag="OE968_003068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HCP7220328.1"
                     /translation="MIIISKENIKYYLIVVFIGILFFKFINTPSDFISSIEGFLKFFS
                     PFLLAILLALLLNPLVMLFEIKFKAHRLLAIFLSYIFIGFILAFAIRLLIPSIANTLN
                     RLINEMPMYTDYIDSFIEKNMSNIYFLKTLIPHIQHSLDNLLKEASNFVGKIPKNFLI
                     YTLSISSMLFNMTMGFILSIYIIYDKEKIALGFKRFLYSSTARNKADNIIEFFRTTHD
                     IFYDYLLGRILDSLIIGIIAFLGFQFVIRIENALFLASIIFLGNIIPYFGPFIGAIPP
                     IAMTILYSPQKTIWVIAFLFILQQLDGNFIEPKVMGNQVGIGAIWVISAILVGQSLFG
                     FIGVFLSVPIAAVVKTYVDKYIDNRLQ"
     gene            8944..9660
                     /locus_tag="OE968_003069"
     CDS             8944..9660
                     /locus_tag="OE968_003069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HCP7220329.1"
                     /translation="MRINKYIASCGIASRRKAEEIILGGRIKVNGSVVKELSFNIDEE
                     KDIVEFDNKKVKPSENYIYIVLNKPEGYITTVKDQFNRPSVIDILKDVRERVYPIGRL
                     DYETSGLLILTNDGDLTYKLTHPKHEIDKMYVASVKGIISDDEIRQFETGLKIEDYTT
                     APAKIRVTKENKEKNYSVCEITIHEGRNRQVRKMCKAINHPVLNLRRISVGKIVLKDT
                     KVGEYRYLTEDEIKYLKSIK"
     gene            9718..10296
                     /locus_tag="OE968_003070"
     CDS             9718..10296
                     /locus_tag="OE968_003070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HCP7220330.1"
                     /translation="MAYAKYLTKITDINKFYLENIINEGDIVIDATMGNGYDTRYLAE
                     KVGEKGFVYAFDIQEEAIKSTRKKLEKEGYTDRVKLIFDGHEKMNQYIKEEVSCVLFN
                     LGYLPRAKHSIITKPDTTLKAIKLSLEMLKENGVISIAIYTGHDGGQEEKDCIYNLVN
                     NLNQDEFNVLESKFLNQVNNPPQLILIEKKKA"
     gene            10690..11562
                     /locus_tag="OE968_003071"
     CDS             10690..11562
                     /locus_tag="OE968_003071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HCP7220331.1"
                     /translation="MEETNEMKDSKHLISNIQSQYTRLSKGQKLIAQYILNNYDKVAF
                     MTACKLGETVGVSESTVVRFANALGYSGYPKLQAALQELIKNKLTTVQRVEMAHDYSD
                     DFAILNKVLKSDIDNIRSTLEEIDERAFKEASNKLLRARKIYILGMRSSFVVAQYLGF
                     YLDIILDNVHIIRMDMGDAFEQIVRINEEDVIVAISFPRYSKKSYQIVNYAKEKGAHV
                     ISLTDSLFAPVASLADNTLLVKSNMASFVDSLVPALSISNALAISVGMKEKEDIKQHF
                     DDLEQIWKRYSVYE"
     gene            12833..13513
                     /locus_tag="OE968_003072"
     CDS             12833..13513
                     /locus_tag="OE968_003072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCP7220332.1"
                     /translation="MQIDVLIIDGDKNSSQELKNFLEGKGINVYLAYNCKDAIIKIFS
                     KKFDLIFLEIILVDGDGWDFCKKVRSITTCPIIHITYINENQSILNALNSGGDDYLIK
                     PLNLEILYAKVKAILRRRDLFLNNNKNNIKLEDYNRASGVIKLENKMIKLTPTENRLL
                     NYFIENAEKTLTIKEIYEHVWMNEYLDDNYSVVVAVSGLRKKIEKDYKNPQKIITIRE
                     VGYYFNKI"
BASE COUNT         5724 a         1347 c         2272 g         4397 t
ORIGIN      
        1 cacttaaaaa tatatctata aaaaaaggaa atgttgattt ggatatggaa gtagaaatag
       61 atttaaaatc acaaataaat ggggcattag gatatttaaa ggactctgga aaggttcaag
      121 atatactaaa tcatctgatt aatttgaaga aaacatctgt tggttaaaaa tatagaaaac
      181 ttatatttat atttttatta tattatataa tattaaagta ccttaaaatc aaaatttgta
      241 aaaccacatt tattatgtta gaatatctta tgatattaaa ttgtaagtgt ataatattat
      301 ttagttacta gattgggggg aaatgatgaa taaagtctat attgtaacaa catatacagg
      361 aactatatta tcttacttaa taaggaatat aagtaaaaag ctgtatacac atgtgtcaat
      421 atcattaaat gaaaatctaa aaccaatgta ttcttttgga aggctaaatc caaggaatcc
      481 atttattgga ggatttgttg aagaaaatat aaatcaagga ttatatgcta taagaaaaaa
      541 cactgtgtgt agggtatatt cgttagaagt agataattta caatatgaaa atctatataa
      601 aaatataaaa ttaattagtg attatagaga agattactat tacgatacaa tggcattaat
      661 atatttacta atgaatattc agagacaatc tgaatataaa tatgtatgtt caaattttgt
      721 tgctgacatg ttagaaaaaa gtgagataga cattttaaat aaacaagcat ttgaagtaac
      781 gccaaatgat ttttataatt tatctggctt aaccttagag tatgaaggtt tattatcaga
      841 atataattct agacaacatt cttatgtatc aaaaatcgca aacatttaaa aacttgattt
      901 agagtttttc atataaaaaa atattgctag ataattaggc tgaagatagt agtttaactt
      961 cgataggatt aagaatttgt aaatcttagt tagaatactt tcttcagttt ttaaatttct
     1021 gctaatattt gtatttttat aatatttttg gatatatata atacagaata gtgcaaaaat
     1081 cccactcctt taggtgcggg atggatagta caaacagtgt ataaaaagta tttatacata
     1141 cacgtataat gttaaatata gttgaataag cagaactata aatatataaa gatatcttaa
     1201 tatataataa atatgataaa tatttatttt ttgtaaatat atggatataa tagtaataat
     1261 aacatttttt agagaggagt attaaatgaa acgatatctt aaaacatatg gagttgcatt
     1321 aataattgta ataatttatg catttattaa attacctgta ctaagattag attttacatc
     1381 tttattttca gtaggaataa ttttctttgt tgtagcagga atactagata tgatgttaga
     1441 tagaaatgaa agagcatcta aaatggctaa atataatttt tcaatagcaa tagctttgct
     1501 tgtgtatatt gtagtagttc cctttataac ttctacacct gtacttcatg caaaatcata
     1561 tagagaacta ttgggaaaag taactgaaag taaatttact gatgacatta gccctgtcag
     1621 tgtaaatgac attcgtcttg tagatgaaga tatggcaatg aaattaggtg acaaaaagct
     1681 tggagaagtt cctgcaatag ggagtgtatc caaattagga aaatttcata tacaaaatgt
     1741 agatggagag ttgtactggg tagcgcctct tgttcacaga gacataatta aatggataac
     1801 atctctaagt ggtacaagtg gttatgtaaa agtatcagct agtaatcctc aagacgtcca
     1861 attagttcaa gaaatagatg gaaagccaat aaagatagtt taccaaccag aagcctactt
     1921 acatcaggat ttacaaagac atttatacat acatggtatt gtaaatgttg gtatgacaga
     1981 tttcactctt gaaataaatg atgaaggaag accttattgg gttgtaagtt tatatgaaca
     2041 taaaattggc tatggaggag caaatgcaac aggaatagcc actgttgatg cagaaactgg
     2101 aaaaataaat gtttatgatg ttaaaaacac gcctaaatgg gtggatagaa tacaaccaca
     2161 aagctttgta acagaccaaa ttaaagactg gggtgtttat gttaatggat ttttaaactc
     2221 tgttatatca gaaaagggag ttttagtacc aacagaaggt acatcactag tttatggcaa
     2281 tgataacagg tcttattggt atacaggtat aacatcttca ggtggagatg aatctacaat
     2341 tggatttatg ttagttgatt ctagaacaaa agaagctaga ttatataaac aaccaggagc
     2401 tactgaaacg gctgcaatga aatcagctga aggtaatgtt caagaaaaaa attatgaagc
     2461 gacgttccct gtaatgtata atatattggg tcagccaaca tatgtatcat cattaaaaga
     2521 taaggctggt cttgttaaga gagttgcatt tgtatctgtt gaagattata atgtacttgg
     2581 aataggtgaa gataagaatg aagcattaag aaactataag gatgcattag aatctaaggg
     2641 taatgattta aaacttgata atgatttaaa agatgaggta ttagaaggca cagtgacaag
     2701 aataagccca gatgtgcgag gtggtaacac taattattat gtaactttag attcaaataa
     2761 agatataata tttagggcta cttcaaaagt atctagcgaa ttgccattga ctcaggttgg
     2821 tgataaagtc aaaatatcgt attcaaaaga agaatctggt gtaatagaaa tgtcagaatt
     2881 tgataaccta aatattgcaa actttgaaga taaaaaagca aaagaaaaaa caggaactga
     2941 tgaaaataca gattccaaag attctgaaaa tcaaggtaat gtataattta aataaaaaga
     3001 ttgataatag tatttaacat agtgatagct aatttttata gaatttaatt ctataaaaat
     3061 tagctatttt attttaattc tttgtaaatt taatgtcata aaattaatat aatattagta
     3121 caactttgca aataatactt caaggagaat gtactatgac gaatatggaa aaagagatat
     3181 tacttttaat tagcagggtt agatgtgtta cagagtctca atttagaaaa atttatggag
     3241 accaaaaaag atacaataaa aaaaatttta aaaaaacttt gagaaaaatg tgtagtgaat
     3301 atacactaaa aaaatatcct tgtgatgtgg attattataa ttataaagac ctctcttatg
     3361 tatactattt aaacggtagt aaacttttta agggagatga tttaataaag gctctagtag
     3421 gatcagaatt agttgttaga atcaatactg caggttgtga tgtaaaaaga ttttaccgaa
     3481 atgttagtgt agatgatgtg aaatacgatt tatttattga atatacagac caatttggta
     3541 atataaagca agttttagtt gatgttgact taaataatga aatagacatt tctaaatacg
     3601 aaaatctttc taaaaaaata gataaatcta caattccatt ttttaaagta ccaaacgttt
     3661 tggtagttac accagataat ctatccgaat taaatgattt agagagatat gataatgagt
     3721 atagcataaa ttttatagat ttaggattaa ataaactatt taattgtata taagctaact
     3781 ttagaaaaga aaactatcga tttgccacat tttgtaaaat aattgttgca atattatata
     3841 gaatatgata aaactatatt aataaattaa ttaaaaataa tgagcctagg gtagaggtag
     3901 ctgtattcaa tagtattcaa taggagctgg taagcgttga taattgatga aagggtatat
     3961 agccgaagaa attttgttga cggacaaatt ttctggactt atgcagaata tgcataaggc
     4021 tgtcactttt aaagtggtga gctacaaggt tacttggtct atgaaattta cacgtccaaa
     4081 gtataccttt gggcgttttt atttatcaaa atttagcttg agggggagaa agcatgagta
     4141 taattgttca aaaatatggt ggaagttcag tagcagatac tgaaaaaata aaatcaatag
     4201 cagaaaatat aatagaacga agaaaagaaa atccacaaat ggtaatagtt gtgtctgcca
     4261 tgggaaaatc cactgatgaa tatataactt tagcaaagga attgagtaat gaacctagta
     4321 agagggaatt agatgcttta atgtctactg gtgaaatgat ttcagcatct ttattatcaa
     4381 tagcattaaa tgcacttgga tgtaaagcta taagttataa tgcttaccag ttaaatataa
     4441 aaacgagtgg tcttcatgga aagtctcaaa ttgatgatat aaacgtaaac agaattaaaa
     4501 atagtttaga tgaaggaaat gtcgtgatag taactggatt tcagggaatc aacgaagatg
     4561 gtgatgtaac cactcttgga agaggtggtt cagatacatc tgctgtagct cttgcggtta
     4621 aattaaatgg aaaatgtgag atatatacag atgttgatgg aatttatttt acagacccaa
     4681 gaaaatattc aaaggctagt aaacttgatg agattgaata tgaagaaatg cttgagttag
     4741 cgagtttagg agcacaagta atgcattcaa gaagtataga gcttgcacaa aaatatggtg
     4801 ttgaaatcta tgtcggacgt acatgtggta cagaaaaagg aacatatata agagggggaa
     4861 aagacatgaa attagaggat aaagtaataa caggattagc tactagtgat gatgacagtt
     4921 ctataacaat aaaagatttt aaagctgaaa atatatctag cttatttgaa gatatagcaa
     4981 ctataggtat aagtgtagat atgataagcc aaactgcacc tattttagat aagataagtg
     5041 tatcatttac agttccaaaa gaagagttgg gagaatgtaa aaagatagta tctaaatata
     5101 cagatgaaga acatgtagtg attgataata atatcactaa attttcttta gtaggtcttg
     5161 gtatgaaaaa tacttctgga gttgctgcta aagtatttaa gatattcaat gaaaatggta
     5221 taatgataaa acttataact acatcagaga ttcgtataac ttgtgctata aattctgatg
     5281 ataagcaagt agctatagaa aaaatagcag aagtatttaa tatataaaat ttggggaggc
     5341 tattatgaaa cttcatggaa ctatgactgt aaataatgat gaattatata ttggaggagt
     5401 gagttgttta gaacttagta aaaaatatca aactccactt tatgtatttg atgaagcttt
     5461 agttagacaa aattgtagag aatatgtaga atattttaag gctagagagg gaaaaaataa
     5521 ggttgcttat gcagggaaag cttttttacc tctttacatg tgtaatctta taaatgaaga
     5581 acaaatgtgt ttagatgtag tttcaggagg cgagttatat acagcttata aatcaaattt
     5641 tcctatggaa aaagttttct ttcatggaaa caataagact aaagaagaaa taaacatggg
     5701 attagattta ggtgtaggta aatttgtggt ggataatttt tatgaattag atttgcttga
     5761 agcattatgt gaagataaag gtaaaactca agagatatac tttagaataa ctcctggtat
     5821 agaagctcat acacatgatt atataaaaac tggacagata gattctaaat ttggatttgc
     5881 tttagtaaat ggagatttat ttagagcaat agaaaaatta agtgaatata aaaatattaa
     5941 acttgtgggt cttcacgctc atataggttc acaaatattt gatgtagaac catacataga
     6001 tacagtggat ataatgatga acttggtaaa agaaataaaa gaaaaattca acatacaact
     6061 aacagaaatt gacctaggtg gaggagttgg cgtttattat agcgaaggag ataaacctaa
     6121 aactataaaa gagttttgtg aaaccataat cactaaagca gaaacttcat gtaaagagct
     6181 tggaatagaa gtacctacat tggtaataga accaggaagg tcaatagttg caaatgcagg
     6241 aagtacattg tatacagtag gttctataaa agatataaaa gatgttaggg tttatgtaag
     6301 tgtagatgga ggtatgacag ataatgtaag accttcgttg taccaagcta gttatgagtg
     6361 tagtattgtg aataaaatta atcatgaggc tatgaatcat gtaacaatag ctggaaaatg
     6421 ttgtgagagt ggagatatat taattggaga tataaacata atggatatta aaagtggaga
     6481 tatacttata acaacatcaa ctggtgcata tggatattca atgtcttcaa attataataa
     6541 aataccaaga gcagcagtag tatcagtatt tgatggaaat gataagataa tttgtaagag
     6601 acaaagctat gaggacttat tagctttaga gatataaaat ggagaagtat ataataaaaa
     6661 ttaaatatta aagtttatta tgagcagatt tgctaggata tgtatctcta aattaatttt
     6721 tggtttattg tatcgttcgt agcatatctg cttatttttt gttttactaa caaatttctt
     6781 gtaataaata taaaatattt taaaaacttt ataattatga taaaatttaa agtatatgac
     6841 aaggagggat ttaatgagag gaagagtaat tttattaata tcgatattat ctatatttct
     6901 tgtaggatgt tcatttaata aaaaagatga aataaattta gtagagcaag gaaaaacata
     6961 tttagaaaaa cataactata aaaaagctat ggaatcatta tcctctgcac tggaagaaga
     7021 tagtactaat gagaatgcaa gagctatgta tatgcaagct atgagaatgt caaatatgac
     7081 ggagtttgaa gaattaaaaa attatgaggg tgcaatcaag gaacttaaac ttatagagaa
     7141 aatcaaaaat ggttcctctg ttattaaaga agaggcaact aaaaagaaag aagagttaac
     7201 taaattagaa aaagaacaaa acgaagcaga ggaacaaaga aagaaaaagg caaaagatac
     7261 ggctggagaa gataggtata gagttgaatc agatgcaagg aaatcttctt atagtggaag
     7321 tagtaaaaat aataaatcta gttctaaaaa taatgataaa aaatcagata gtaataagtc
     7381 tgacaatagt aacagttctt ctcaaaatca agaaaagcca aataatagta atccaacacc
     7441 agcaccaact ccacaagata ctactggtgg ttcagatagt ggtggaaatt ctcaaaactc
     7501 aaataatcaa taagtataaa atatatgcat aaatttaatg aacaaattat atattataaa
     7561 aaatatctct tagcaatttt ttcttactaa gagatatttt ttgagaaata atttaataaa
     7621 taacagttaa attttaaact aaaaattaaa gtcacagtag agataagcta ttgtaaacga
     7681 ttatctatat atttatcaac ataagttttt acaacagcag ctattggtac tgaaagaaaa
     7741 actcctatga aaccaaatag agattgtccc accaaaatag cagatattac ccatatagct
     7801 cctataccaa cttgattacc cataactttt ggttctataa aatttccatc taattgttgc
     7861 aatataaata gaaatgcaat gacccatata gttttttgtg gactatataa tatagtcatg
     7921 gctattggag ggattgcacc aataaaagga ccaaaatagg gaattatatt acctaagaat
     7981 attattgaag ctaaaaataa agcattttct attctgataa caaattgaaa tcctaaaaat
     8041 gcaattatac caataataag agagtctaat attctaccaa gtaaataatc atagaaaata
     8101 tcatgagtag tcctaaaaaa ttctataatg ttatctgcct tgtttctagc agtagaagaa
     8161 tatagaaatc tcttaaatcc caatgcaatt ttttctttgt catatataat gtatatagat
     8221 agtataaatc ccattgtcat attaaatagc atagaagata tactaagtgt atagattaag
     8281 aagtttttag gaattttacc aacaaaatta cttgcttctt ttaataaatt atctaaacta
     8341 tgttgtatat gaggaattaa agtttttaga aaatatatgt ttgacatatt tttttctata
     8401 aaactatcta tataatcagt atacataggc atttcattta tcaatctatt taatgtatta
     8461 gctattgatg gaattaataa cctaatggca aaggctaaaa taaaacctat aaatatataa
     8521 gataaaaaaa tggctaaaag tctatgtgct ttgaatttta tctcaaaaag catcacaagt
     8581 ggatttaaaa gtaaagcaag taaaatagct aataaaaatg ggctaaaaaa ctttaagaat
     8641 ccttcaatac tagatataaa gtctgatgga gtattaataa atttaaaaaa taaaattcca
     8701 ataaacacga ctattaaata atattttata ttttcctttg aaataataat cacttcctta
     8761 aaatagtgtt tagtcagcta ttacatatta atagtatgtg aaaagaaatt acaattattt
     8821 aggaaaatta aataattttt ttgcttgttt ttaattaagg tctagtatag tataataatg
     8881 tagcaaaatt aacattgata aaaatattaa acacacataa tttaagataa ggaaggatta
     8941 agtatgagaa ttaataagta tatagcttct tgtggaatag catcaagaag aaaagcagaa
     9001 gaaataattc ttggaggaag aataaaggta aatggaagtg tagtaaaaga gttatctttt
     9061 aatattgatg aagaaaaaga catagtagaa tttgataata aaaaagtaaa accaagtgaa
     9121 aattatatat atatagtatt aaataaacca gagggatata taactacagt aaaagaccaa
     9181 ttcaatagac ccagtgtaat agacatactt aaagatgtaa gggaaagagt atatccaata
     9241 gggagattag attatgaaac tagtggttta ttaatactta ctaatgatgg cgatttaaca
     9301 tataagctta cccatccaaa gcatgaaatt gataaaatgt atgtggcaag tgtgaaggga
     9361 attataagtg atgatgagat aagacaattc gaaacaggac taaaaataga agattacaca
     9421 acggcacctg ccaaaataag ggtaactaaa gaaaataaag aaaaaaatta ttcagtgtgt
     9481 gaaataacta tacatgaggg tagaaataga caagtaagaa aaatgtgcaa agctataaat
     9541 catccagttt taaatttaag aaggatttct gtggggaaaa tagtattaaa agacaccaaa
     9601 gttggagaat atagatacct aacagaagat gaaataaaat atttaaaatc aataaaataa
     9661 gataaaaata aattgagaaa aaatgaaata aagttaatag tagggagaaa tagtattatg
     9721 gcatatgcaa agtatttaac taaaattaca gatataaata aattttattt agaaaatatt
     9781 ataaatgaag gtgacatagt aattgatgct actatgggaa atgggtatga tacaaggtat
     9841 ctagctgaga aggttggaga aaagggcttt gtatatgctt ttgatataca agaagaagca
     9901 ataaagtcta caagaaagaa actagagaaa gaaggatata cagatagagt aaaattgata
     9961 tttgatgggc atgaaaaaat gaatcaatat ataaaagaag aagtttcatg tgttttattt
    10021 aatttgggtt atcttccaag agcgaaacat tcaattataa ccaaaccaga tacaacttta
    10081 aaggctataa agttaagttt agaaatgtta aaagaaaatg gagtaataag cattgccata
    10141 tatacagggc atgatggagg tcaagaagaa aaagattgca tatataacct tgtcaataat
    10201 ttaaatcaag atgaatttaa tgttttagaa tctaagtttt taaatcaagt caataaccca
    10261 ccacaattga ttttaattga aaagaaaaaa gcataataaa tactaaaaaa cttgacaaga
    10321 ttgtattaag agttaatata tatagtgtga cctattaaaa atactttaaa taataagtat
    10381 acaacagttt attctcaaaa caaaatatac atctaaatat gcaaaataag atagataact
    10441 tttaaatgag taaaaattga aaaatttaaa agaaatattg gataaatatt aaaaaatgca
    10501 aggaaagatg gtataataaa tttaatcgaa aatactatgt gaagtataag gtacagaaaa
    10561 gttagaattt tatgagttta agaagctatg ataaaaacta agatgaaatt gagataaaaa
    10621 ataaaatttt tagagaaaaa gacagtgtta ataaaacaaa atagtttata taactaaaag
    10681 gagaaaaaaa tggaagaaac aaatgaaatg aaggacagta aacatttgat atcaaatata
    10741 caatctcaat atacgagatt gagtaagggt caaaaactta tagcacaata cattttaaat
    10801 aattatgata aagttgcatt tatgactgca tgtaaattgg gtgaaactgt aggagtaagt
    10861 gagtctacag ttgtaagatt tgcaaatgca ttaggttata gtggatatcc taaattacaa
    10921 gctgcacttc aagaactcat aaaaaataaa ctaactacag tacaaagagt tgaaatggca
    10981 catgattatt ccgatgattt tgcaatacta aacaaagttt taaaaagtga tatagataat
    11041 ataaggtcta cactagaaga aattgacgag agagcgttta aagaagcttc taacaaactt
    11101 ttaagagcga gaaaaatata tatacttgga atgaggagtt cttttgtagt agctcaatat
    11161 ttaggttttt acttagatat aatacttgac aatgttcata taattagaat ggatatggga
    11221 gatgcttttg agcagattgt aagaataaat gaagaagatg taatagttgc tattagtttc
    11281 cctcgttatt ctaagaaatc ttatcaaatt gtcaattatg ctaaagaaaa aggagcccat
    11341 gtaatatcat taacagatag cttatttgcg ccagtagcat cacttgcaga taacactctt
    11401 ctagttaaga gtaatatggc ttcatttgta gattctctag ttccagctct tagtatttca
    11461 aatgctcttg ctatatctgt tgggatgaag gaaaaagaag atattaaaca gcattttgat
    11521 gatttagagc aaatttggaa aagatattct gtgtatgagt aaagtttgtg tattaataag
    11581 gctatgaaat tgagaatcat agccttatta ataaatacta gattatcact taaaaaataa
    11641 attttcgttt aaataataca aataaatatt tcgagactca aaacataaag atgtattctg
    11701 aatatatctt tactacatca actaatttat taaagaaagc atttcccttc atggagagtg
    11761 ctttttttat ttctctaaac aatatcattt ccttaattaa caattataaa attaatttta
    11821 tttgtattta agtatataat atcttattaa aattctatta aaatatgtat ttctatcttt
    11881 tttgttcact ataatatgtg tcttttagta ttttatttta actttgacaa agaagttgaa
    11941 aaatttaaaa atcatagaat tagtagttag gtatgaaatc ttgatttttt aagtagccat
    12001 ttttggggaa agggaaactt ttttagaaat ataatacttt ataaaaataa aataaagttt
    12061 ttataaatat taagacatag aatataaagc ttttgtaata atgtatttac caaaataata
    12121 caatatatct tatattataa ctatataaat tatataaatc aatacttaaa cataccaata
    12181 gaggcatttt aaaaaaaaca taaatttata atataaaatt gttttaagct ccctttcccc
    12241 aaaataggaa atttttatta gtatttaata atgattttta atttttaata taatattaaa
    12301 gaattattta agaatattta atctctaaag cttaaattac aataatatta taaaaataaa
    12361 agtgatatat tgtgtaataa tcgaaatttt atactttggt taaaataatt ttatatatag
    12421 tgcctaatgt ataacctaat gctcgtagac aataatgtgg atattatcaa atttattttt
    12481 ataatagaaa ttttaattta tatctatatt aaattgttaa agatataatt atgagaataa
    12541 aaaatatagc cttgaattat ataattgtat atgcttatct ttatacagta aataaaaaat
    12601 caaatgaaat accaaataaa gtgtatatct taaaacaatt tactagagat acaaggatgc
    12661 tatgtgaatt ttgaagtgtg cagtttagat aataaatata tataaataat aaagaaaatg
    12721 gatttatagt atttaaaatt tcttataagg gtaaaaaatg ctattagaaa atgtactaaa
    12781 aatatttttc caattcttta tagaaaaata atgatattta ggagagattg taatgcaaat
    12841 tgatgtattg ataattgatg gagataagaa tagttctcaa gagctgaaaa attttttaga
    12901 aggaaagggg ataaatgtct atttagcata taattgtaaa gatgctatta taaaaatatt
    12961 tagcaagaaa tttgacttaa tatttttaga gataatttta gttgatggtg atggttggga
    13021 tttttgtaaa aaagttagaa gtataactac ttgcccaatt attcatataa cttatataaa
    13081 tgaaaatcaa agtattttaa atgctttaaa ttctggagga gatgattatt taataaagcc
    13141 tttaaattta gaaatattat atgcgaaagt gaaagctatt ttaagaagaa gagatttatt
    13201 tttaaataat aataaaaata atataaaact agaagattat aatagagcta gtggagtaat
    13261 aaagttagaa aataaaatga taaagttaac tccaacagaa aatagattat taaattactt
    13321 tatagagaat gctgaaaaga ctctaactat taaggagata tatgaacatg tatggatgaa
    13381 tgagtattta gatgataatt atagtgtagt ggttgctgtg agtggattaa gaaagaaaat
    13441 agagaaagat tataaaaatc ctcaaaaaat tataacgata agagaagtag ggtattactt
    13501 taacaagata taaagcttta taaacagaat gaatgataag gcatagataa tatgttagta
    13561 tattacaaga gtttttgttc taacgatata tttgtaaaat tagatttaat ttacttaatt
    13621 aaattatagc agtagaataa atataaaaaa tgtctgaaat attatagaca tcagtaaaat
    13681 atataaaact ataatataag tcgtaataat aaaacaaatg aatattaatt aataaaaaga
//
LOCUS       DAJMZY010000108        13722 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.109, whole genome shotgun sequence.
ACCESSION   DAJMZY010000108 DAJMZY010000000
VERSION     DAJMZY010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13722)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13722)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13722
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.109"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            106..246
                     /locus_tag="OE968_003073"
     CDS             106..246
                     /locus_tag="OE968_003073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220333.1"
                     /translation="MGIIESASKLAEMVHLLAVEKGITDIEAWDEAVKEYSKIYEERR
                     NE"
     gene            complement(421..741)
                     /locus_tag="OE968_003074"
     CDS             complement(421..741)
                     /locus_tag="OE968_003074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HCP7220334.1"
                     /translation="MKLKTISLPELNNLDPTLESTFIKMGEEQGELAECIGKFRNLSG
                     ENNDLDEVDIIKKTAKELMDVAQTCVTMMFKLEEQYGINLDEIRKEHIKKLEKRGYIK
                     NMDK"
     gene            complement(861..1598)
                     /locus_tag="OE968_003075"
     CDS             complement(861..1598)
                     /locus_tag="OE968_003075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HCP7220335.1"
                     /translation="MDANSLKDLIANHNNIVFFGGAGVSTESNIPDFRSSTGLFSQKL
                     NKQFTAEQLVSHTFFVRYPEEFFEFYKDKLIYPNAKPNNAHIALAKLEEMGKLKAVIT
                     QNIDGLHQMAGSKNVLELHGSVHRNYCTKCGKFFDLESMLNLGGNIPYCDNCGSIVKP
                     DVVLYEEALDSDVITKTISAISNADLLIIGGTSLAVYPAASFIDYYKGDYIALINKAN
                     TVYDKSASLVINKPIGEVLYEAVLRQI"
     gene            1813..3636
                     /gene="acd"
                     /locus_tag="OE968_003076"
     CDS             1813..3636
                     /gene="acd"
                     /locus_tag="OE968_003076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosaminidase"
                     /protein_id="HCP7220336.1"
                     /translation="MKKKAALATLAMLPLGVVNAHADGDIGIVTINYLNVRNEPTAES
                     SIAFVAKKDDKVLIKDSSNGWYKIKAESGQEGWASSKYIAKSNSDSLRTSTNKEKQVI
                     SNSLNMRNGAGTSYRVITVLKKGQKVEVISESNGWSKIKYDGRLGYVSSSYLGDVSNS
                     TNKSKTKQVNTTSLNVRSGPNTSYGLLGKLPKGSKVEVISESNGWSKIKYNGKDAYVS
                     SMYLSDVSQSNSDNSSQSNDKKNTDKVVNTASLNVRSGPGSTYSKLGKVYKGSKVTVL
                     SESSGWAKINFNNKEAFVVGNYLSTSADTSNNNSNSNSDNSSNSNGNNSSSSGQVNGM
                     SGISGAKIDYKSLSYTLESHISKQVEKAASGGNVIAPSNRKSTPSPEFSTFSAQRTSS
                     FVNASSSDIEYYLNPKNFTNTTKGMMQFLKINSYRDGISESSLNSYLNGLSSSVFKNQ
                     GAAFINAAKKYNIDVVYLVSHAMWETAYGKSTLAQGQTLTSYKGQPLSKPVKVYNFFG
                     IGAIDKSANVSGAEAAYSNGWTSVEATIDGSAKWISQNYVNSSKYNQNTIYKMKWNYD
                     YTWHQYATDVNWANGISGIMENLIGLYGGGSSLVFEVPQYK"
     gene            3851..8149
                     /locus_tag="OE968_003077"
     CDS             3851..8149
                     /locus_tag="OE968_003077"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HCP7220337.1"
                     /translation="MESIKEYLDKLEINNSGLGKQLKEVYINRVVYFKEDKIVYFYLT
                     SKDIVSHELLDKFKEELMYKLDYFKDMRMKIRFTGLERKSNKDVIKKYWNNILYILKY
                     LCPSIAGWYKQVEFLCLEEELKIKLPKGIFYERLMKKNVTYVLKTVLSEELGLDLNIT
                     IEKAVDEKVNKERLIRINDREMEEKIRALEIGKVNNCEENEEESYVIKSDVDENLIYG
                     DNANAMIENIVELNASSGTVAVVGDIFDVDTKELKNGKILMIASITDYTSSISCKLFL
                     TDTNKDGVLENVKKGAYLKIKGDIVYDTYQREISMMISGIRKETRIEREDKSEEKRVE
                     LHAHTQMSSMDAICSVKKLVERAAKWGHSAIAITDHGVVQGFPDAMNAGKSNNIKILY
                     GVEGYLVEDDSLIIEDANDKELSQTFVVFDIETTGFSNTNDKITEIGAVKIENFKIVD
                     RFSELINPEKDISYKIQELTGITNELIKDKPTIEEVLPKFMEFVGDSVLVAHNAEFDT
                     GFISQKCREQGLLYNNKKVDTLMLARVMLPNLKRHRLNVVAKELGIPLLNHHRAVDDA
                     EATALIFNKFLQMLTEKGAKTLSDVNNILGKIDYTKLSTNHITLIAKNSIGIKNLYKI
                     ISDAHVNHFFRAPRILRSVLNEYKEGLIIGSACEAGVVFQAVKKNVSDEEMKKIIDLY
                     DYIEVMPIDNNRFMIDKGEVKDEEELRELNRKLIDTAKKFDKIPVATGDVHFLDKHEA
                     VLRKVLKYSQGFKVDEEETYLHFRTTDEMLEEFSYLGEELAYEVVVENSNLIADMVED
                     IKPIPDDTYPPIIEGSDVELREMCYKKAKRIYGDPIPEIVQKRLDRELNSIISNGYAV
                     MYIIAQKLVAKSLSDGYLVGSRGSVGSSFAATMSDITEVNPLPAHYICENEDCKYSFF
                     YEIGEWGSGVDLPDKDCPKCGRKLAKNGHDIPFEVFLGFEGDKEPDIDLNFSGNYQPT
                     IHKYTEELFGEGYVYRAGTIGTVAEKTAFGYARKYVEENNISVPNAEVLRLSNGCTGV
                     KRTSGQHPGGVMVIPDYKDVYDFTPIQYPANDTSCGVITTHFDYHSISGRILKLDILG
                     HDGPTIIRMLEDMTGINITEIPLDDKETMSLFTSTEALGVTPEEINCPIGCLAVPEFG
                     TKFVRQMLLDTKPTTFAELVRISGLSHGTDVWVNNAQDLVREDIVGLKDVISTRDDIM
                     NYLIFKGLPPKMSFTIMESVRKGKGLKPEHIEEMKKNNVPEWYIGSCKKIKYMFPKAH
                     AVAYVMTSFRIAYCKVHYPEAFYATYFTTKVEDFDADLIVKGLDAIKSKINEIESLGN
                     DATTKEKGMLTVLEVALEMYARGIKLLPVDIYKSDATEFIVVGEKTLLPPMAAIQGLG
                     GNAAINIQNERKNGEFISKEDLRKRTKISKTVIETLTNHGSLENMSERNQLSLF"
     gene            8353..8814
                     /locus_tag="OE968_003078"
     CDS             8353..8814
                     /locus_tag="OE968_003078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HCP7220338.1"
                     /translation="MKKNLEATIEEIVTKITDEHGFEMVDVEYVKEAGEYYLRVYIDK
                     EEGISLNECELVSRELSPILDEKDPIKENYFLEVSSPGLDRALKKDRDFVRYQGRDVD
                     LKLYKPLNGCKQFEGELVGLTEDNNIKIIANGKEMEFNRKDVAIVRLAIKF"
     gene            8844..9998
                     /gene="nusA"
                     /locus_tag="OE968_003079"
     CDS             8844..9998
                     /gene="nusA"
                     /locus_tag="OE968_003079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HCP7220339.1"
                     /translation="MNHEFMEALDELVVDRGIDKEILIDTIEQALLTAYKKNFGSAQN
                     VRVEFDRDKGDIKVFSQRVVVDESDLYDTFLEIELADAREINPNYELGDIIEHEVTPK
                     NFGRIAAQTAKQVVVQRIREAEREIVYNEFIEKENEIVTGEVARANKNVVYVNLGRIE
                     GIMTQSEQIPFENYKAGQKIKFYILEVKKTNKGPQIVVSRSHPGLVKRLFEEEVPEIY
                     EGIVQIKSVAREAGSRTKMAVRSIDEKIDPIGACVGPKGLRVKNIVDELGDEKIDIIK
                     YSEDPAEFISAALSPSKVVRVDIDEDEKSALVIVPDYQLSLAIGKEGQNARLAAKLTN
                     WKIDIKSESQAEQEMLNLENSKEIEAEDVEAEFIDQEELDTSEDNFSEEE"
     gene            10005..10286
                     /locus_tag="OE968_003080"
     CDS             10005..10286
                     /locus_tag="OE968_003080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HCP7220340.1"
                     /translation="MILKKVKKVPQRKCIACQDRDSKKELIRIVKNKEGKIFLDPTGR
                     ANGRGAYVCKSSECLKKAIKSKALNKAFKIDVPDEVYDNLLMELEEYEK"
     gene            10276..10587
                     /locus_tag="OE968_003081"
     CDS             10276..10587
                     /locus_tag="OE968_003081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal L7Ae/L30e/S12e/Gadd45 family protein"
                     /protein_id="HCP7220341.1"
                     /translation="MKNNKEKVLSFLGLATRAGKIVSGDDSTLLDLKKGKVNLILIAE
                     DASNNTKKLFKDKSTFRNIPYLFFSTKEEIGFAIGKSPRAVVGIKDENFSKKIIELIE
                     I"
     gene            10609..12549
                     /gene="infB"
                     /locus_tag="OE968_003082"
     CDS             10609..12549
                     /gene="infB"
                     /locus_tag="OE968_003082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HCP7220342.1"
                     /translation="MSKTRVYQIAEELNISNEELINKLAELDINVTDKDSVLEGEELE
                     LALEMLGEDLSQENGNVIEIDGKLTVQVLATKLDKSPSEIIMKLMKMGTMATINQEIS
                     FEIAALAAKDYGFELTVAESDDTEALEIEALMEIEEDKEEDLKPRPPVVTVMGHVDHG
                     KTSLLDAIRKTDVISGEAGGITQHIGASEVKINGHKIVFLDTPGHEAFTSMRARGAQV
                     TDIAILVVAADDGIMPQTVEAINHAKAAGVPLIVAINKIDKPGANPDKVKQELADQGL
                     LVEDWGGEVIAVPVSAKKKEGIDTLLEMVLLVAEMEELRANPNKRAVGTVIEAELDKG
                     RGPVATVLVQGGTLTVGDPIVAGVACGKVRAMINAKGKRVKTAGPSTAVEILGLSEVP
                     QGGDQFVEVPTDKIARSVAARRQQIVRDEMLKSTQRLSLDALFSQMSEGSIKDLNIVI
                     KADVQGSVQAVKQSLEKLSNEEVQVKVIHGGVGAVTESDILLAAASNAIIIGFNVRPV
                     PGAESLGEKENVDIRTYTIIYKAIEDIQAAMTGMLDPEYVDEETGKAEIREIYKISGV
                     GTVAGCYVTNGKIFRNCKVRLVRDSIIIHEGELAALKRFKDDVKEVNSGYECGMSFVN
                     YNDIKEGDIVEAYITKEVERKL"
     gene            12592..12972
                     /gene="rbfA"
                     /locus_tag="OE968_003083"
     CDS             12592..12972
                     /gene="rbfA"
                     /locus_tag="OE968_003083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HCP7220343.1"
                     /translation="MASYNRTRRIAEEIRKVVSTMLINGVKDPRITSMVSVTDVEVTN
                     DLRYAYVYVSILGGDEESTLTGLKSAGGYIRREVGKNIKLRYIPEIVFKLDDSIEKGM
                     YMDSLIKRVNEKNAQQNEDENYDE"
     gene            12953..13630
                     /locus_tag="OE968_003084"
                     /pseudo
     CDS             12953..13630
                     /locus_tag="OE968_003084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438308.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
BASE COUNT         5478 a         1561 c         2581 g         4102 t
ORIGIN      
        1 aataaaaaaa tttttattta ttagagtttt tggaaataat aataacagat attataatta
       61 attaacagtt tttgtaagta tttgacaata gagagggtgt aacaaatggg aataatagag
      121 tcagcatcaa aattggctga gatggttcat ttattggctg ttgaaaaggg gataactgat
      181 atagaagcat gggatgaagc tgtgaaagaa tacagcaaaa tttatgaaga aagaagaaat
      241 gaatagaatg ataaaaaatg aaaacttgat gataaaaaat aactttattt aaagaaattc
      301 aatttttata gaagtattaa aaataatata aataaaaaga tggtatttca aatgtaagta
      361 aaaaatcatt ttgggatacc atccttatta tttattttaa taatatataa gtaataaatc
      421 ttacttatcc atatttttta tgtaacctct tttttctaac ttttttatat gctccttacg
      481 tatttcatca agattaatac catattgttc ttctagctta aacatcatag taacacatgt
      541 ctgcgctaca tccattagtt ccttagcagt tttctttata atatcaactt catctaaatc
      601 attattttct ccacttagat ttctgaattt acctatacat tcagctaatt caccttgttc
      661 ttcacccatt ttgataaatg tagattctag tgttgggtct aaattattaa gctctggtaa
      721 agatatagtt tttagtttca taaaagctcc tttcaagtta ttcgtattta tactaaaaca
      781 tcataacaaa aataatacta aaaaaaaact ttaaattcaa cataaaaact tacatatata
      841 ataaaaatca tgaaataaat ctatatttgt cttaatacag cctcatataa aacttctcca
      901 ataggtttat ttattacaag agaagctgac ttatcataga ctgtatttgc tttattaata
      961 agagcaatat aatcaccttt gtaataatct ataaaacttg ctgctgggta cacagctaat
     1021 gatgtacctc ctataatcaa taaatcagca ttacttatag cagaaattgt tttagtaatg
     1081 acatcactgt caagagcttc ctcataaagt actacatctg gttttactat agaaccacag
     1141 ttgtcacagt aaggaatatt acctcccaga tttaacatag attctaagtc aaaaaactta
     1201 ccacatttag tacaataatt tctatgtaca gaaccatgaa gttctagcac atttttactt
     1261 ccagccattt gatgaagtcc atcaatattt tgagttatga cagctttaag cttacccatt
     1321 tcttcgagtt ttgctaaagc tatatgagca ttattgggtt ttgcattagg atatattaat
     1381 ttatccttat aaaattcaaa aaattcttct ggatatctaa caaaaaaagt atgtgaaact
     1441 aattgttcag cagtaaattg tttattgagt ttttggctaa ataatccagt agaacttcta
     1501 aagtctggaa tattagattc agttgaaaca cctgctccac caaaaaatac aatattattg
     1561 tgattagcta ttaagtcttt taagctattt gcatccatag ttacacctcc aaattattat
     1621 atataaattg tactacatat taggtcgttt atgttttatt aatttaaata aatatatagt
     1681 ttaataagtt aaataaaggg aatataaata aaatgtatac agagtataaa tagacaatat
     1741 ttactaaaat aacaagttgt cgtataatta tattaaaatt gttttagtgt ataagaaggg
     1801 cgggggaagt acgtgaagaa aaaagcagct ttagcaacat tggctatgtt acccttaggt
     1861 gtggtaaatg cacatgctga tggagatata ggtatagtga ctataaatta tttaaatgta
     1921 agaaatgaac caactgccga aagtagcata gcctttgttg ctaaaaaaga tgataaagtt
     1981 ttgattaaag actcttctaa tggatggtat aaaataaaag ctgaatctgg acaagaaggt
     2041 tgggcttcat caaaatatat agcaaaatca aatagtgact ctttaagaac gtctacaaat
     2101 aaagaaaaac aagttatttc aaatagttta aatatgagaa atggagcagg tacaagttac
     2161 agagtaataa ctgtactaaa aaaaggtcaa aaagtagaag taatatcaga gagtaatgga
     2221 tggtctaaaa tcaaatatga tggaagacta ggatatgtat ctagctctta tttaggagac
     2281 gtttcaaact caactaataa atcaaaaact aaacaagtga atacaacttc actaaatgta
     2341 aggagtggac caaatacaag ttatggtttg ttaggcaagt tgccaaaagg aagtaaagta
     2401 gaagtaatat cagaaagtaa tggatggtcc aaaataaagt ataatggaaa agatgcctat
     2461 gtatctagta tgtacttatc ggatgtaagt caaagtaatt cagacaattc tagtcaaagc
     2521 aatgataaaa agaatactga taaggttgta aatacagctt ctttaaatgt aagaagtgga
     2581 ccaggttcta catatagtaa gttgggaaaa gtttataaag gaagtaaagt aactgtacta
     2641 tcagaaagta gtggatgggc taagattaat tttaacaata aagaagcatt tgtagtaggc
     2701 aattatttat ctacctcagc agatacttca aataataact caaatagtaa ctctgataac
     2761 agttctaata gtaatggtaa taattcttca tcatcaggcc aagtaaatgg tatgtcaggt
     2821 ataagtgggg ctaaaattga ttataaatct ttgagttata ctttagaatc tcatataagt
     2881 aaacaagttg agaaagcagc atcaggagga aatgtgatag ctccaagtaa taggaaaagt
     2941 actccaagtc ctgagtttag tactttttca gctcaaagaa caagctcatt tgtaaatgca
     3001 agttcaagtg atatagaata ttatttaaat cctaagaatt ttacaaatac tactaaaggt
     3061 atgatgcagt ttttaaagat taacagttat agagatggta tttcagaatc aagtcttaac
     3121 tcgtatctta atggtttatc ttctagtgta tttaaaaacc agggagcagc ctttataaat
     3181 gctgccaaga agtataatat agatgttgta tatctagtat ctcatgctat gtgggaaact
     3241 gcttatggta agtctacact tgcccaaggt caaacattaa catcttataa gggacaacct
     3301 cttagtaagc cagttaaagt atacaatttt tttggtatag gagcaataga taaaagtgct
     3361 aatgtttcag gtgcagaagc agcgtattcc aatggctgga ctagtgtaga agctacaata
     3421 gatggctctg caaagtggat atcacaaaat tacgtaaata gttctaagta caatcagaat
     3481 actatctaca agatgaagtg gaattatgat tatacatggc atcagtatgc aactgatgta
     3541 aactgggcta atggaatttc tggaattatg gaaaatttaa ttggtcttta tggaggagga
     3601 agtagtttgg tttttgaagt tcctcaatat aagtaataca taaataaaaa atatagacta
     3661 tgggtagttt tcattttatt taaattatct atagtctttt tgtatataat ttataatctg
     3721 taaatttaat gttaacaaaa cttttatgtt ataatattaa ttctaagtaa atataagtga
     3781 gtaataggta gaaatagata aaaagtggta ataatatata taaagataat tttgagaaag
     3841 gaggatatat atggaaagta ttaaggaata tttggataag ttagaaatta ataatagtgg
     3901 tcttggaaag caacttaaag aagtttatat aaatagagta gtttatttta aggaagataa
     3961 gatagtttat ttttatctaa cttctaaaga tattgtttct catgaacttt tagataaatt
     4021 taaagaagaa ttgatgtata aactcgatta ttttaaagat atgaggatga agataagatt
     4081 tactggtctt gaaagaaaat ccaataaaga tgttataaaa aaatattgga ataatatatt
     4141 gtatatatta aagtatcttt gtccatctat tgcagggtgg tataaacaag tagaatttct
     4201 ttgtttagaa gaagaattaa aaataaaact tccaaaaggt atattttatg agcgattaat
     4261 gaaaaaaaat gtaacttatg tacttaaaac cgtgcttagc gaagagttgg gattagattt
     4321 aaatataaca atagaaaaag ctgttgatga aaaggtaaat aaagaaagac tcataagaat
     4381 caatgataga gaaatggaag aaaaaattag ggctttagaa attggaaaag ttaataactg
     4441 tgaagaaaat gaagaggaaa gctatgtcat taagtctgat gtagatgaaa atttaatcta
     4501 tggagataat gcaaatgcta tgattgaaaa tatagttgaa ttaaatgcat cttctggaac
     4561 agttgcagtt gttggagata tatttgatgt tgacactaaa gaacttaaaa acggaaaaat
     4621 acttatgata gcttcaatta cagattatac tagctcaata agctgtaaac tttttttaac
     4681 agatacaaat aaggatggag tacttgaaaa tgttaaaaaa ggagcatact taaaaatcaa
     4741 gggtgacata gtttatgata catatcaaag agaaattagt atgatgatta gtgggataag
     4801 aaaagaaact agaatagaga gagaagataa atcagaggaa aaaagagtag aactccatgc
     4861 acatacacaa atgtcttcta tggatgctat ttgttctgtt aaaaagcttg tagagcgtgc
     4921 agccaaatgg ggtcattctg ctattgctat aacagaccat ggtgttgtac aaggatttcc
     4981 agatgctatg aatgcaggta agtcaaataa tataaaaata ctttatggag tagaagggta
     5041 cctggttgaa gatgattctc tcattataga ggatgcaaat gataaagaac tttcgcagac
     5101 atttgttgta tttgacatag agacaactgg cttttctaat acaaatgata aaataactga
     5161 gattggtgct gtaaaaatag aaaactttaa gattgtagat agatttagtg agttaataaa
     5221 tcctgaaaaa gatatttctt ataagataca ggaattgaca ggaataacta atgaattaat
     5281 taaagacaag ccaaccattg aagaagttct tcctaagttt atggaatttg ttggagatag
     5341 tgtattagta gcacataatg cagagtttga tactggattt atatcgcaaa aatgtaggga
     5401 acaaggcttg ttatataata acaaaaaagt agatacactt atgttagcaa gagtaatgtt
     5461 gccaaactta aaaagacata gattaaatgt cgttgcaaaa gaacttggta ttcctctttt
     5521 aaatcaccat agagcagtgg atgatgctga agctacagca cttatattta ataagttttt
     5581 gcagatgctt acagaaaaag gtgcaaaaac tctaagtgat gtaaacaata tacttggaaa
     5641 gattgattac acaaagctta gcacaaatca tataaccttg atagcaaaaa attctatagg
     5701 tataaaaaat ttatataaaa taatttcaga tgcacatgta aatcattttt ttagagcacc
     5761 aagaatcctt agaagtgtat taaatgaata taaagaagga ttaataattg gttcggcttg
     5821 tgaagctggg gtggtttttc aagctgtaaa gaaaaacgtg tctgatgagg aaatgaaaaa
     5881 aataatagat ttatacgatt atattgaagt aatgcctata gataataata gatttatgat
     5941 tgataaagga gaagtaaagg acgaagaaga gttaagggag ttgaatagga aactaattga
     6001 tacagccaaa aaatttgaca aaattccagt agctactggg gatgttcatt ttttagacaa
     6061 acatgaagct gtcttaagaa aagttcttaa atattctcaa ggttttaaag tagatgaaga
     6121 agaaacttat ttacatttta gaacaacaga tgaaatgttg gaagagttta gttatcttgg
     6181 agaagaattg gcatatgaag ttgtagttga aaatagtaat ctgattgccg atatggttga
     6241 agatataaaa cctataccag atgatactta tcctccaatt atagagggct cagatgtgga
     6301 gttaagagaa atgtgttaca aaaaagccaa acgaatctat ggagacccaa taccagaaat
     6361 agttcaaaaa agactggata gagaattaaa ttcaataata agcaatgggt atgcagttat
     6421 gtatattata gctcaaaaac tggttgcaaa atctctttca gatggatatt tagttggttc
     6481 aagaggctca gttggctcat cttttgcagc tactatgagt gatataacag aagttaatcc
     6541 tcttccagca cattatattt gtgaaaacga agactgtaaa tattcattct tttatgaaat
     6601 aggtgaatgg ggctcaggtg ttgatttacc agacaaggat tgtccaaagt gtggaagaaa
     6661 acttgctaaa aacggtcatg atattccatt tgaggttttc ttaggttttg aaggtgataa
     6721 ggaaccagat atagacttaa atttctcagg aaattatcag ccaacaattc ataaatacac
     6781 agaagaacta tttggagagg ggtatgtata tagggctggg actataggta ctgtagcaga
     6841 aaaaacagct tttggatacg caagaaaata tgtggaagaa aataatataa gtgtaccaaa
     6901 tgcagaagta cttaggcttt caaatggatg tactggagta aaaagaacct caggacaaca
     6961 tcctggtgga gttatggtta taccagacta taaagatgta tacgatttta cacctataca
     7021 gtatccagca aatgatactt cttgtggtgt tataactact cactttgatt atcattcaat
     7081 aagtggtaga atacttaaac ttgatatact tggacacgac ggtcctacca ttataaggat
     7141 gcttgaagat atgactggaa taaatataac agaaattcct ttagatgata aagagactat
     7201 gtctctattt acatctacag aagcattagg tgttacacca gaagaaataa actgtcctat
     7261 aggttgcctt gctgtaccag agtttggaac taagtttgta cgacaaatgt tacttgacac
     7321 aaaacctact acatttgcag aacttgtacg tatatctggt ctctctcatg ggacagatgt
     7381 ttgggtaaat aatgcacaag acttagttag agaagatata gttggattaa aagatgttat
     7441 atctacacga gatgacataa tgaactattt aatatttaaa ggattacctc ccaaaatgag
     7501 ctttacaata atggagagtg taagaaaagg taaaggttta aaaccagaac acattgaaga
     7561 aatgaaaaaa aataatgttc cagaatggta tataggctca tgtaaaaaga ttaagtacat
     7621 gttcccaaaa gcacatgctg ttgcttatgt aatgacatca tttagaattg catattgtaa
     7681 agttcactat ccagaagcat tttatgcgac ttattttacg acaaaagttg aggattttga
     7741 tgcagattta attgttaaag gattagatgc tataaaatca aaaataaatg aaattgagtc
     7801 actgggaaat gatgcaacca caaaagaaaa aggtatgttg accgttttag aagttgctct
     7861 tgaaatgtat gctagaggaa taaaattatt accagttgat atatataaat cagatgcaac
     7921 tgagtttata gttgtaggag aaaaaacatt acttccacca atggcagcaa tacaaggtct
     7981 tggaggaaat gcggctataa acatccaaaa tgaaagaaaa aatggtgaat ttatatcaaa
     8041 agaagatttg agaaagagaa caaaaatatc aaaaacggta atagaaactc ttactaatca
     8101 tggttcactt gagaatatga gtgagagaaa tcaattgtca ttgttttaag ttagcccaaa
     8161 aagttgcaaa taaaagaatt ttatgatatc atagtataga aaatagtata ctttgcagaa
     8221 actaagagtg agacagctgt tctcactctt ttattttaaa tatattatta aaaagctggt
     8281 ttatttttat taaatatatt ttatttaaga ttatataaac tggtcattta caattgaata
     8341 ggaggaactt taatgaaaaa aaatttagaa gctacaattg aggagattgt aactaaaata
     8401 acggatgaac atggatttga aatggttgat gttgaatatg taaaagaagc aggagaatac
     8461 tacttaagag tatacataga taaagaagaa ggaatatctt taaatgaatg tgaattagtt
     8521 agtagagaat taagtccaat actagatgaa aaagacccta taaaagaaaa ttacttttta
     8581 gaggtatctt ctccagggct tgatagagca ttaaaaaaag acagagattt tgttagatat
     8641 caaggtagag atgtagattt aaaattatat aaaccattaa atggatgtaa gcaatttgaa
     8701 ggtgaacttg taggattaac agaagataat aatataaaaa tcattgcaaa tggtaaggaa
     8761 atggaattta atagaaaaga tgttgctatt gtcagattag caataaagtt ttagtggtat
     8821 attaaatagg gaggatataa aaaatgaatc atgaatttat ggaagcatta gatgaattag
     8881 tagttgacag aggtatagat aaagaaatac ttatagatac tatagaacaa gctcttttaa
     8941 ctgcatacaa gaaaaacttt ggttcagcac aaaatgttag agttgaattt gatagagaca
     9001 agggagatat aaaagtattt tctcaaagag ttgttgttga tgaatcagat ttatatgata
     9061 ctttcttaga aatagagtta gcagatgcta gagagataaa tcctaattat gaattaggtg
     9121 atattataga acatgaagtt acacctaaaa actttggaag aattgcagct caaacagcaa
     9181 agcaagtagt tgttcaaaga ataagggaag ctgagagaga aatagtgtat aatgaattta
     9241 tagaaaaaga aaatgaaata gttacaggag aggttgctag agcaaataaa aatgttgttt
     9301 atgtaaatct tggaagaata gaaggtataa tgactcaaag tgaacaaata ccatttgaga
     9361 attataaagc aggtcaaaaa ataaaattct atatacttga agttaaaaag actaacaaag
     9421 gacctcaaat agttgtatca agaagtcatc cgggtctagt aaagagattg tttgaagaag
     9481 aagttcctga aatatatgaa ggaatagttc aaataaaatc tgtagcaaga gaagcagggt
     9541 caagaactaa aatggcagta agatctatag atgaaaaaat agacccaatt ggagcttgtg
     9601 ttggaccaaa aggacttaga gtaaaaaata tagtggatga acttggcgat gagaaaatag
     9661 atataataaa atatagtgaa gacccagcag agtttatatc agcagcactt agcccatcaa
     9721 aggttgttag agtagatata gatgaagatg aaaagtctgc cttagtaatc gttccagatt
     9781 atcagttatc gcttgctata ggtaaagaag gtcaaaatgc aagactagca gcaaaattga
     9841 ctaactggaa aatagatatt aagagcgaat ctcaagcaga acaagaaatg ttaaatcttg
     9901 aaaattccaa agaaatagaa gctgaggatg ttgaagctga atttatcgac caagaagagt
     9961 tagatacttc agaggataat tttagtgaag aagagtaagg agggatgatt ttgaaaaaag
    10021 taaaaaaagt gcctcaaaga aaatgcatag catgtcaaga tagagactct aaaaaagagc
    10081 ttataagaat agttaaaaat aaagaaggaa aaatattttt agacccaaca ggaagagcca
    10141 atggaagagg agcatatgta tgtaaaagct ctgaatgtct aaaaaaagct ataaagagta
    10201 aagcattaaa taaagctttt aaaatagatg ttcctgatga agtctatgat aatctactta
    10261 tggagttaga agaatatgaa aaataataaa gaaaaagtac tttcgttctt agggctcgca
    10321 actcgtgcag ggaaaatagt gtctggtgat gattcaactt tgcttgacct taaaaaagga
    10381 aaagtaaatt tgattttaat cgcagaagat gcatcaaata atactaaaaa actttttaaa
    10441 gataaatcaa cttttagaaa tattccatat ctattttttt caacaaaaga ggaaatagga
    10501 tttgcaatag gaaaatctcc aagagcagtt gtaggaataa aagatgaaaa tttttctaaa
    10561 aagataattg aactaataga aatttaaaat aaaatagggg gtgatcttgt gtcaaaaaca
    10621 agagtatacc aaatagcaga agaattaaat atatcaaatg aagagcttat aaataagtta
    10681 gctgaattag atataaatgt aactgacaaa gattcagtat tagaaggtga agagttagaa
    10741 ttagcacttg aaatgttagg tgaagattta tctcaagaaa atggaaatgt tatagaaata
    10801 gatggaaagt tgacagtaca agtattagca acgaaattag ataaatctcc atcagaaata
    10861 attatgaagc ttatgaaaat gggaactatg gcaacaataa atcaagagat aagttttgag
    10921 attgctgctt tggctgccaa agactatgga tttgaattaa cagtagctga aagtgatgat
    10981 acagaagctt tagaaataga agctttaatg gaaattgaag aagacaaaga agaggattta
    11041 aaacctagac caccagttgt tacagttatg ggacatgttg accatggtaa gacatcttta
    11101 ctagatgcaa taagaaaaac tgatgtgatc tcaggtgaag ctggaggaat aactcagcat
    11161 ataggtgctt cagaagttaa aatcaatgga cacaaaatag tatttttaga tactccagga
    11221 catgaggctt tcacatcaat gagagcaaga ggagcacaag ttacagatat agcaatatta
    11281 gtagttgcag cagatgatgg tataatgcct caaacagttg aagctataaa ccatgctaaa
    11341 gcagcaggtg tacctttaat agttgctatt aataaaatag ataaaccagg tgcaaaccca
    11401 gataaggtta aacaggaatt agcagaccaa ggattattag ttgaagactg gggtggagaa
    11461 gtaatagcag ttccagtatc agctaagaaa aaagaaggaa tagatacact tttagaaatg
    11521 gtattattgg ttgctgaaat ggaagagtta agagctaatc caaataaaag agcagtagga
    11581 actgttatag aagctgagct tgataaagga agagggccag ttgcaacagt acttgttcaa
    11641 ggtggtactt taacagtagg tgacccaatc gttgcaggtg ttgcatgtgg taaagttaga
    11701 gcaatgataa atgcaaaagg taagagagta aaaacagcag gaccatctac agcagtcgag
    11761 atattaggtc tatcagaagt tccacaagga ggagaccaat ttgtcgaagt tccaactgat
    11821 aagattgcta gaagtgtagc agcaagaaga caacaaatag ttagagatga aatgttaaaa
    11881 tcaactcaaa gattatcact agatgctcta tttagtcaaa tgagtgaagg ttctataaaa
    11941 gaccttaata tagttataaa agcagatgta caaggttcag tacaggcagt taaacaatct
    12001 ttagaaaaat tatcaaatga agaagttcaa gttaaagtaa tacatggtgg tgttggagct
    12061 gtaacagaat cagacatatt acttgcagca gcttctaacg caataataat aggattcaat
    12121 gtaagaccag ttccaggtgc agaatctcta ggagaaaaag aaaatgttga tataagaaca
    12181 tatactataa tatacaaggc aatagaagat atacaagcgg ctatgactgg tatgttagac
    12241 cctgaatatg ttgatgaaga aacaggaaaa gctgaaataa gagaaatata taaaatatct
    12301 ggtgttggaa cagtagctgg atgttatgtg actaatggta agatatttag aaattgtaaa
    12361 gtaagattag ttagagatag cataataata catgaaggtg agcttgcagc acttaagaga
    12421 tttaaagatg atgtaaaaga agttaattct ggatacgaat gtggtatgag ttttgtaaat
    12481 tataacgaca taaaagaagg cgatatagta gaagcttata taactaaaga agtagaaaga
    12541 aaattataaa ttcgtatcaa agaaaatcag ttagtaaaga aggtcgatgg tatggcatca
    12601 tataatagaa caagaaggat agcagaagaa ataagaaaag tcgtaagtac tatgcttata
    12661 aatggagtaa aagaccctag aataacatct atggtgagtg taactgatgt agaagttaca
    12721 aatgacctaa gatatgctta tgtatatgta agtattctag gcggagatga agaatccaca
    12781 ctaacaggtc ttaaaagtgc tggaggatat ataagaagag aagtaggaaa aaatataaaa
    12841 cttagatata ttcctgagat agtatttaaa cttgatgatt caatagaaaa aggaatgtat
    12901 atggatagcc ttataaaaag agttaatgaa aaaaatgctc aacaaaatga ggatgaaaat
    12961 tatgatgaat aatatggata gtattataaa ctatatttat gagggtgact attttatagt
    13021 tacctctcat atcagtccag atggagacaa tattggttct acactttcaa tgtattatac
    13081 attgaagaat ttaggaaaaa atgtatatta tgtacttgat gatgaagctc cattaaattt
    13141 aaggtttttg gttgaaggtg taaaaatcta taagtctaat gaatttaata tgaagaacta
    13201 ttctctaatt gcacttgatt gtggggataa gatgagaata tgtgtgagtg atgaaatcaa
    13261 aaataatgca tcaaaattaa tctgtattga ccatcatgct agtaatgatt catatggaga
    13321 tttaaattat gtagatattg atgcatcttc tacatgtgaa ttagtttata atttattagt
    13381 tagatttcag caaataaaag atattaatat tataaatgaa gatatagcaa catgtttata
    13441 tacaggtctt gtaactgata ctggaaactt ttcgtattca aatgtacatg caagtagctt
    13501 tgaaatggca aaaaatttac ttgttttagg tgcacaaaaa aatactataa tacaaaatat
    13561 atatcaaagc aattcttctg gttattacaa attattagga gaagctctaa agggtttgga
    13621 gatatttgat taaaaaatag ttacgcacac tcgtgacttt agtcatgagt tagtagctaa
    13681 aatagtcagc atatagggaa acttatatgt agagatagga ta
//
LOCUS       DAJMZY010000109        13435 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.110, whole genome shotgun sequence.
ACCESSION   DAJMZY010000109 DAJMZY010000000
VERSION     DAJMZY010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13435)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13435)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13435
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.110"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            complement(253..906)
                     /locus_tag="OE968_003085"
     CDS             complement(253..906)
                     /locus_tag="OE968_003085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCP7220344.1"
                     /translation="MKVDPLTTQVYDYISKKIQNGEYEANQRITESEICKSIGVSRTP
                     AREALTRLAGENLLEKIPNKGFVVKEFQEKEKLDTYSVIGVLDALAGSSALQNLTESD
                     LVKMEELTEMMAVSIKYKNYNSYLKLSNEFHDIYITKSDNQVLVNLLNSLRYNFMSKS
                     YTSDNEDELYKMLTYSNNQHIEVVKSMRENDLENVERILREHWKTIPIAEMKKEKLL"
     gene            complement(1151..3016)
                     /locus_tag="OE968_003086"
     CDS             complement(1151..3016)
                     /locus_tag="OE968_003086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 13 protein"
                     /protein_id="HCP7220345.1"
                     /translation="MQSVIEYNSWDKNFKAPFGALKFDEELTICVKVNEGYNIKSISL
                     EINREEEMRTITLNEELDNDKLGKCFCGKIEKFDGTGVYFYYFKVDVEMDGQIKTLFY
                     GKNRDNGYSCEYNYSDINKYQITVYKDFKVPTWYKEGILYHIFVDRFNNGNRSGKVDN
                     PKKNSFIYGNWEDTPMYIKDSQGDVIRWDFHGGNLRGIINKLGYLKKLGVSILYLSPI
                     FEASSNHKYDTGDYKKIDPMFGDEDTFKELIDKAKEKGISIVLDGVFSHTGADSKYFN
                     MYGNYNSLGAYQSKESPYYSWYMFEEFPQKYKSWWDVKTLPNINELEHSYMDYIIYDN
                     DSVINKWVNMGIKGWRLDVADELPTKFIRELKKELKKADDDSILIGEVWEDASNKISY
                     GQRRSYLLGEELDSVMGYPFRNNMFSFLKGEINSYELCNRYMQIKENYPKESFRSNLN
                     LIGTHDVTRAKTELNDDVDLVKLAVAIQMTFEGVPYIYYGDEAGLCGGVDPDNRRTYP
                     WKNEDEDMLNFYRDVIKIRNKNKLLSSGNTEFIYTNNDSVFSFIRVNENNDRMLILVN
                     RSENVESISLCIESSFIEEIPIKYSLKNANSTIQIENNELKVDLDSKSFRIFRVN"
     gene            complement(3021..5441)
                     /locus_tag="OE968_003087"
     CDS             complement(3021..5441)
                     /locus_tag="OE968_003087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan phosphorylase"
                     /protein_id="HCP7220346.1"
                     /translation="MVTISKKKFKQKFEVKMYSLYAQSIKEATDEQLLNVLCSLLKDE
                     IAKKWVATKLDKKKEVYYFSLEFLIGRQLKSNLLNLNIEEEVREGLSELGINLDDLIE
                     TEVDPALGNGGLGRLAACFLDSMASLNISGQGYGIRYKYGLFEQKFVNGYQVEVPDNW
                     LTEGRYAWETVRPNEATMVKFGGEVELIKEGSHLKVIHKNYLPVMAMPYDIPIIGYQN
                     QCINTLRLFKSEIPKRDFGELTSNALNYSGSYEEALKHKYYTEEISQVLYPDDSNYAG
                     KLLRLKQEYFFVSAGIQDIIRKYKKNKLNINNLFDKVAIHINDTHPTLCIPELMRILL
                     DEENLSWDEAWEITKKTVSYTNHTIMSEAMEKWPVSMMKELLPRIYMIIEEINRRYVE
                     ELNNKGYDQDRIKRMSIIDCDNINMANLCIVTSHSVNGVAKLHTHILETEVLKDFYQD
                     EPNKFNNKTNGIAHRRWLISSNPQLSNLITDLIGDSWKKDTLQLKNIEKFKNDSSVLQ
                     RLDDIKYNNKANLAKFIKDKYDLNVDPSSIFDVQVKRLHAYKRQLLNIFNVLHMYHEL
                     LDNPNLNLDPRTFIFGAKAAPGYYLAKCIIKFINSVASTINNDVRVKDKLKVVFLENY
                     GVSLAEIIIPAANVSEQISTTTKEASGTSNMKFMMNGAITLATLDGANVEICEQVGKE
                     NMFLFGLSAEQVLNYNKYGGYSSLDLYHSNMDIKRVVDDLINGFIPNLGEEGRSIYNS
                     LTTYNDEYFVLRDFENYGQAQADINRLYRDKEKWNKMSLVNIANSGFFSSDRTISEYA
                     KDIWFKRV"
     gene            complement(5455..6897)
                     /gene="glgA"
                     /locus_tag="OE968_003088"
     CDS             complement(5455..6897)
                     /gene="glgA"
                     /locus_tag="OE968_003088"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011053260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HCP7220347.1"
                     /translation="MKVFYVTAECWPFAKTGGLGDVSYALPKELKKEGVDVRVIMPKY
                     STIPSYLKDQLKEIAVFSVRVGWRNQYCGLLEMELDGVKFYFIDNEFYFRREDERKSI
                     YGYGDDAERYTFFTDAVLEAISRIDFYPDVIHINDWHTGMLPLILKERYATLEGYKNI
                     KTMYTIHNLQYQGVFDKHVLYDILDLPQKYFDNGDIEYYGSINFMKAGINFADKIITV
                     SPTYANEIQTSFYGEQLDGLLRKESGKLKGILNGIDYDLNDPAKDKDIFVHYDVDSID
                     KKVENKLRLQDILGLKKDSSIPLIGIVSRLVSQKGFDLIAYMMPELMREDLQIVVLGT
                     GEHQYQSMFNYYDSNFSDKVSARITFNASLAQQIYAASDMFLMPSLFEPCGIGQMLAM
                     RYGSLPIVRETGGLRDTVTPYNKFTGEGNGFSFKNYNAHEMFFCLKNAIKVFKDKEKW
                     IKLVENAMKTDNSWKKSAKEYIETYRDICD"
     gene            complement(6926..8056)
                     /gene="glgD"
                     /locus_tag="OE968_003089"
     CDS             complement(6926..8056)
                     /gene="glgD"
                     /locus_tag="OE968_003089"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HCP7220348.1"
                     /translation="MRNECLGIINLNKKGDPAINKLNYGRPIASTPIAGRYRIIDFAL
                     SNMINSGITKVGIFAKEKYRSLTDHIGSGKDWDLSRKKGGLSIFSPENTKYRNTYSHR
                     EGDIYTILANLDYIEKSEEEYILIAPSYMLCNLNYSQALEYHKKSHNDITIIYKNVNN
                     ANKDFAGNLTLNLDSNNRVINVGNNLGKFPRANICMETYIMKREDFVECIYNIVNKGN
                     YCYLEEFIIEEAENMKIGAYEYTGYLKCVNSVESYFEMSKDLLNLEVADELLYSERKI
                     FTKEKNESPTIYTDSAKVENSFIASGCLIEGTVKDSIIFRKVNVEKGTVIENSIVMQN
                     CVIKSNAKLYNAILDKNTSVSNGKELRGDEKYPLVVEKNTNI"
     gene            complement(8058..9218)
                     /locus_tag="OE968_003090"
     CDS             complement(8058..9218)
                     /locus_tag="OE968_003090"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HCP7220349.1"
                     /translation="MKKEMLAMILAGGQGSRLGVFTKRIAKPAVSFGGKYRIIDFVLS
                     NCSNSGIDTVGVLTQYRPLILNSHIGMGSHWDLDRINGGVYVLQPFMNEKEGNWYNGT
                     AHAIYQNMDFVDTYNPEYVLILSGDHIYKMDYSKMLKFHKEKGSKATIAVIEVPWDEA
                     SRFGIMNTNEDSSIYEFEEKPSEPKSNLASMGVYIFDWKMLRNYFKEAEKNPEINYDD
                     FGKNLIPKMLEDNVGMYAYPFKGYWRDVGTIQSLWDANMDIIKSPETLDLADPKWKIY
                     TNTMAMPPQYIGKNANVHRSMIADGCRILGEVGNSVLSHGVVVGKGSKVIDSVIMPNV
                     VIGENVTIEKAMIGECATINDNVQIKNVNNEINVVSEYENIEPRCVLIEGGL"
     gene            complement(9989..11032)
                     /locus_tag="OE968_003091"
     CDS             complement(9989..11032)
                     /locus_tag="OE968_003091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH/Band 7/PHB domain protein"
                     /protein_id="HCP7220350.1"
                     /translation="MGTKIVLSIVLIVVVVAISLTCIRVIKQSKVGIIMRLGKFQKVA
                     ETGVHFLIPFLDKMAYVIDLREIVIDFPPQPVITKDNVTMQIDTVVYYKVTDPVRYVF
                     EIANPIAAIENLTATTLRNIIGELDLDETLTSRDIINVKMRTILDEATDKWGIKVNRV
                     ELKNIMPPQDIQVAMEKQMRAERERREAILQAEGNKSAAILQAEGEKQSAILTAEAKK
                     EAMVRVAEGEKESAILVAEGEAEAIRQTAIAKAQGEAEMIKRTQMATAEGLKLVFSAM
                     KEADIDNNILALKSMEALEKMAEGKSTKLVLPSEAVNFLGTFKGIKEVMSDDNKEVLD
                     IKEVLNDNESLKK"
     gene            complement(11053..11499)
                     /locus_tag="OE968_003092"
     CDS             complement(11053..11499)
                     /locus_tag="OE968_003092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HCP7220351.1"
                     /translation="MKLIWLIVAVLFGIAEMLTPSLTLIWFSVGAVILIFLSSFIESI
                     FLQILIFAVISIAMLVVATKKIVKKDKGYKSNTNLQAMMSKKGIVTEEISPNNTGLVV
                     VEHETWTAISIDGEKIEKGSTVEVLKIEGVKLVVKKVDATVNVTNQ"
     gene            complement(11677..13257)
                     /locus_tag="OE968_003093"
     CDS             complement(11677..13257)
                     /locus_tag="OE968_003093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional ADP-dependent NAD(P)H-hydrate
                     dehydratase/NAD(P)H-hydrate epimerase"
                     /protein_id="HCP7220352.1"
                     /translation="MLIGTSKLSRNVDTACVEEVGIPMIVLMENAVISAMKNMDIDMY
                     NSYTVVCGVGNNGGDGLGIARHLNTYGKEVNVFLVGNLEKLSECSKINYNVLLNMGIN
                     IININKNDLSEKNYGEENEVDKIIKVEKQNIIKNKNLTIFKDRVSKSDVVVDAIFGTG
                     LKRDITGIFKEVIDIVNDNSKNTYSIDIPSGIDSDNGNVLGTCIRANKTISFEFYKRG
                     FLNYDTSALIGDVVVEKIGVPDFITRKYHDEEFITDKTFVKNNIRRRDKHGFKSDFGK
                     VSIVAGSKGFYGASFIATESAVKSGSGLVTLISSEDVQEKVSIRLTEAMTLNFEEERL
                     NKLLNSSDAIGFGPGMGDNSQTFDKLLKIVENSNCPIVLDADGLNVMKDRCYKFLEWK
                     NRFVITPHLGEMARLTGDSIGYIREHRVDVAKEFAQKYNLVVLLKGYQTVITDGKKTY
                     INPTGNSCMATGGMGDCLLGMITSFIGQGMDILEATVSGAYIHGYIGDKLSKAMYTVN
                     ATDLISNISLTMKELLDI"
BASE COUNT         4274 a         2433 c         1275 g         5453 t
ORIGIN      
        1 taaataattt tcctattttt gtattttaat tttaatataa aatttattaa attttttaat
       61 tgataaaata aattctatat ttatgatatt aaaattctat aagttcattg atttatatat
      121 gttaatttaa atacattatt ctatcgtagt gccttagagt ttttatttgt atttaaagtt
      181 aaatttattc ttgtttttcc tttaatattt aatagtaaaa caacaaaatt ataaaaaaaa
      241 taaagagaaa ctttataaaa gcttctcttt tttcatctct gctataggta tcgttttcca
      301 atgttctctc aaaattcttt caacattttc taaatcattc tccctcatag attttactac
      361 ttcaatatgt tgattattgc tgtatgtcaa cattttatat aactcatctt cattatcact
      421 agtatatgac tttgacataa aattatatct taaagagttc aatagattta ctaacacctg
      481 attatctgat ttagttatgt atatatcgtg aaattcatta cttaatttta aatagctatt
      541 gtaattttta tactttatag agaccgccat catttctgtt aattcttcca tttttactag
      601 gtctgattca gttaaatttt gtaatgctga agaaccggct aacgcatcca atactccaat
      661 tacggaatag gtgtctaatt tctccttttc ctgaaattct tttactacaa atcccttatt
      721 aggtattttt tctagtaaat tttcacctgc taacctagtt aatgcttctc tcgctggtgt
      781 tctactaact ccgatagatt tacaaatctc agattcagta attctctgat tagcttcata
      841 ttctccattt tggattttct ttgatatata gtcatatact tgagttgtaa gtggatctac
      901 cttcataaga cgttcctcca tattaagatt ataaaagtta aatctcccta caactttggt
      961 agagagttca gttttatctt actaatttat ataatatcac aattatgata ttttttatac
     1021 ttctttgtaa tattttgaaa tactaaaatt cttatgataa tttatacaaa aaaagtagaa
     1081 aaagttttga taaaacaaaa ctctttccac attcgcctta ttttctattt atttttctaa
     1141 aaaaagatat ttaatttact ctaaaaattc taaatgattt agagtctaaa tctactttca
     1201 actcattatt ttcaatttgt atagtactat ttgcattttt aagactatac tttataggta
     1261 tttcctcaat aaaactactc tctatacata atgatatact ttccacattt tcacttctat
     1321 ttactaaaat taacattcta tcattatttt cattaactct aataaaagaa aatacagaat
     1381 cattattagt atatataaat tctgtatttc cagaacttaa aagtttattc ttatttctaa
     1441 tttttataac atctctataa aaattaagca tatcttcgtc ttcatttttc catggataag
     1501 ttcttctatt atctggatca acacctccac aaagacctgc ttcatctcca taatatatat
     1561 atggtactcc ttcaaatgtc atctgtatag ctacagcaag cttcactaaa tctacatcat
     1621 catttaattc cgttttagct cttgtaacat catgtgttcc aattaaattt aaattagacc
     1681 taaatgattc ttttggataa ttttctttaa tctgcatata tctattacaa agttcatatg
     1741 aattaatttc tccttttaag aaagaaaaca tgttatttct aaaaggataa cccataacag
     1801 aatctaattc ttcacctaat aaataacttc ttctctgacc atagctaatc ttatttgatg
     1861 catcttccca tacttcacct ataagaattg agtcatcatc tgcctttttt aattcctttt
     1921 ttaactctct tataaactta gttggtaatt cgtctgcaac atctagtctc cagcccttaa
     1981 tacccatatt tacccattta tttataacgc tatcattgtc atatattata taatccatat
     2041 agctatgttc taattcattt atatttggca atgtcttaac atcccaccaa cttttatatt
     2101 tttgaggaaa ttcttcaaac atataccatg aataatatgg agattcttta gattgatatg
     2161 ctcctaaact attatagttt ccatacatat taaaatattt actatctgct ccagtatgac
     2221 taaaaactcc atctaatact attgatatac ctttttcttt tgctttatca ataagttctt
     2281 taaatgtatc ttcatctcca aacattgggt caattttttt atagtcacct gtatcatact
     2341 tatgattact agaggcttca aatatagggc ttagatatag tatacttaca cctaattttt
     2401 ttaaatatcc aagtttattg attatccctc ttaaatttcc accatggaaa tcccatctta
     2461 taacatcccc ttgactatcc tttatgtaca taggtgtatc ttcccaattt ccatatatga
     2521 aactattttt tttaggatta tcaaccttac cactacgatt tccattattg aatctatcta
     2581 caaatatatg ataaagtatt ccttctttgt accatgttgg tactttaaaa tctttataaa
     2641 cagtgatttg atatttatta atatcactat aattatattc acaagaatat ccattatctc
     2701 tgttttttcc ataaaataaa gtctttattt gaccatccat ttcaacatca actttaaagt
     2761 aataaaaata aacacctgta ccatcaaact tttcaatctt accacaaaag cactttccaa
     2821 gtttatcatt atctaattct tcatttaaag ttattgttct catttcttct tctctattta
     2881 tttctaggga aatagacttg atattgtatc cctcatttac tttaacacaa atggtcaatt
     2941 cctcatcaaa ttttaaagct ccaaacggag ccttaaaatt tttatcccaa gagttatatt
     3001 ctattacact ttgcatttaa tcacaccctt ttaaaccaaa tgtcttttgc atactcagaa
     3061 attgttctat cagaagaaaa aaatccagag ttagctatat taactaaaga cattttattc
     3121 catttttctt tatctctata taacctgttt atatctgctt gagcttgacc ataattttca
     3181 aaatctctca atacaaaata ctcatcattg taagtagtga gtgaattata aatacttctt
     3241 ccttcttcgc caagattagg aataaatcca tttattaaat catctactac cctttttata
     3301 tccatattag aatgatatag gtcaagtgaa gaatatccac catatttatt ataatttagt
     3361 acttgttctg cactaagtcc aaataaaaac atattttctt taccaacctg ttcacatatc
     3421 tctacatttg caccgtcaag tgtagccaaa gttatagcac cattcatcat aaacttcata
     3481 ttacttgttc cagatgcttc cttagttgta gttgaaattt gctcactaac atttgctgct
     3541 ggtattatta tttctgctaa tgatactcca taattctcta aaaatactac ttttaacttg
     3601 tcctttactc taacatcatt atttatagta cttgcaacag aatttataaa tttaattata
     3661 catttagcca aataatatcc tggtgctgct tttgcgccaa atataaaagt tcttgggtca
     3721 agattcaaat taggattatc aagtaattca tgatacatat gaagtacatt aaatatattc
     3781 agtaactgtc ttttatacgc atgcaatctc ttaacttgaa catcaaatat cgaacttggg
     3841 tctacattta aatcgtattt atcttttata aactttgcta gatttgcttt attattgtat
     3901 tttatatcat caagtctttg taaaacagag gaatcatttt taaatttttc aatatttttt
     3961 aattgtaatg tatctttctt ccatgaatca ccaattaaat ctgtaattaa attgctaagt
     4021 tgaggatttg aacttataag ccatcgccta tgtgcaattc cattagtctt attattaaat
     4081 ttatttggtt catcttgata gaaatctttt aatacctctg tttcaagaat atgagtatga
     4141 agcttagcaa ctccatttac actatgactt gtgacaatac ataagtttgc catattgata
     4201 ttgtcacagt ctattatact cattcttttt attctatctt ggtcatatcc tttattattt
     4261 aattcctcta catatcttct atttatttct tctattatca tataaattct tggtaatagc
     4321 tctttcatca tacttacagg ccatttttcc attgcttctg acattatagt atgattagta
     4381 taggacactg tttttttagt tatttcccat gcttcatccc aagataaatt ttcttcatca
     4441 agcaaaattc tcataagttc tggtatgcat aaggtaggat gtgtatcatt tatatgaatt
     4501 gctaccttat cgaataaatt attaatattt aatttgttct ttttatattt tcttattata
     4561 tcttgtatcc ctgcacttac aaaaaagtat tcttgtttca acctcaacaa cttacctgca
     4621 tagtttgaat catcaggata taatacctgt gatatttcct cagtataata cttatgtttt
     4681 aaagcctctt catagctacc agaataattt agagcatttg aggtaagttc accaaaatct
     4741 ctctttggta tttcactctt aaacaatctt aaagtattta tacattggtt ttggtatccg
     4801 attattggta tatcataagg cattgccatt acaggaaggt agtttttatg aattactttt
     4861 aaatgactac cttccttgat taattctacc tcaccaccaa acttcaccat tgttgcttca
     4921 tttggtctta cagtttccca tgcatatcgt ccttctgtaa gccagttatc aggcacttct
     4981 acctgataac catttacaaa tttttgttca aacagaccat atttatacct tattccatat
     5041 ccttgaccac ttatgttcaa agatgccata gaatctaaaa agcaagctgc taatctacca
     5101 agtccaccat ttcctaaggc tgggtctact tcagtttcaa ttaaatcatc caagttgatt
     5161 cctaattcag ataaaccttc tctaacttct tcttcaatat ttaaatttaa taaattagat
     5221 tttaactgtc tccctattaa aaattctaaa ctaaaataat aaacttcttt tttcttatct
     5281 aactttgtag caacccattt ttttgctatc tcatctttca atagactaca taatacattt
     5341 aacaattgtt catcagtagc ttccttgata gattgtgcat ataagctata catttttact
     5401 tcaaattttt gcttgaattt ctttttgctt attgttacca aaaaaaccac tcctttaatc
     5461 acatatgtct ctatatgttt ctatatactc cttagctgat tttttccaac tattatctgt
     5521 tttcattgca ttttcaacta atttaatcca tttttctttg tccttaaata ctttgattgc
     5581 atttttcaaa cagaaaaaca tctcatgagc attgtaattt ttaaaactaa atccattgcc
     5641 ttctccagta aatttattat aaggtgttac tgtatctcta agccctccag tctctctaac
     5701 tattggtaaa gaaccatatc tcatagctaa catttgacct ataccacaag gctcaaataa
     5761 tgatggcatt aagaacatat cacttgcagc atatatctgt tgagccaatg atgcattaaa
     5821 agtaattcta gctgatactt tatctgaaaa attagaatcg taatagttga acattgattg
     5881 atattgatgt tctccagttc ctaaaacgac aatctgtaaa tcttctctca taagttctgg
     5941 catcatgtat gctattaaat caaatccttt ttgagaaact aatctcgaaa ctatacctat
     6001 caacggaata gatgaatctt ttttaagtcc caatatatct tgtaatctca atttattttc
     6061 tacttttttg tcaattgagt ctacatcata atgaacaaat atatctttat cttttgcagg
     6121 gtcatttaaa tcataatcta taccatttaa tatacctttt aattttcctg actcttttct
     6181 aagtaatcca tctaattgtt caccataaaa agatgtttgt atttcatttg cataagtagg
     6241 actaacagtt ataattttat ctgcaaaatt tataccagct ttcataaaat ttattgagcc
     6301 ataatactct atatctccat tatcaaagta tttttgtggt aagtccaata tatcatataa
     6361 aacatgctta tcaaatacac cttgatattg gagattatgt atagtataca tagtttttat
     6421 atttttatac ccctcaaggg ttgcatatct ttcttttaga attaatggta acatccctgt
     6481 atgccaatca tttatatgta ttacatctgg ataaaaatca attctactta tagcttctaa
     6541 aactgcatct gtaaagaaag tatatctttc tgcatcatct ccatatccat agatactctt
     6601 tctttcatct tctcttctaa aataaaattc attatctata aagtaaaatt ttacaccatc
     6661 taattccatt tctaaaagac cacagtattg atttctccat ccaacacgta cactaaacac
     6721 agctatttct tttagttgat cttttaaata acttggtata gttgaatatt tgggcattat
     6781 tacccttaca tctacacctt ctttttttaa ttctttaggc aatgcataag aaacatctcc
     6841 taatcctcca gtttttgcaa agggccaaca ctctgctgtt acataaaaaa ccttcattag
     6901 tcattccccc ttctaaaaaa tttatttata tatttgtatt cttttccact acaagaggat
     6961 atttttcatc tcctcttaat tctttcccat ttgatacact cgtattttta tctaatattg
     7021 cattatatag ttttgcattt gactttatta cacaattttg cattactatt gagttctcta
     7081 taactgttcc tttttcaaca tttacctttc taaatatgat actatctttt acagtacctt
     7141 ctattaaaca accagatgct ataaagctat tttctacttt agcactatct gtataaattg
     7201 taggtgattc attcttttct tttgtaaata tctttctttc agaatataat aattcatctg
     7261 caacttctaa atttaataaa tctttgctca tttcaaaata tgattcaaca gaatttacac
     7321 attttagata tcctgtatat tcataggctc ctattttcat attttctgct tcttcaataa
     7381 taaattcttc taaataacaa taattgcctt tatttacaat gttatatata cattcaacaa
     7441 aatcttcacg cttcataata tatgtctcca tacatatgtt tgctctaggg aacttaccta
     7501 aattatttcc tacatttatt accctattgt tactatctaa atttagagtt aagttaccag
     7561 caaaatcttt atttgcatta tttacatttt tatatattat agttatatca ttatgagatt
     7621 ttttatggta ttccaatgct tgagaataat ttaaattgca tagcatatag cttggagcta
     7681 ttaaaatata ttcttcttca ctcttttcta tataatctag attagctaag atagtatata
     7741 tatcaccttc tctatgtgag taagtatttc tatacttagt gttttctgga ctaaaaattg
     7801 ataggccacc tttttttcta cttaaatccc aatctttacc actacctata tggtctgtta
     7861 atgatctgta tttttctttt gcgaatattc caactttagt gattcctgaa tttatcatat
     7921 tagataaagc aaagtctatt attctatatc ttccagctat tggtgtagat gctattggtc
     7981 ttccatagtt aagtttgttt attgctgggt ctcctttttt gtttaaattt attatcccta
     8041 aacattcatt tctcatctta aagacctcct tctattaata cgcatctagg ttcgatattt
     8101 tcatactcag aaactacatt tatttcatta tttacattct ttatctgaac attatcattt
     8161 atagttgcac actcacctat catagctttt tctatagtta cattttcacc tattacaaca
     8221 tttggcatta ttactgaatc aattacttta cttcctttac caacaacaac tccatgtgat
     8281 aatacagagt tacctacttc acctaaaatt ctacaaccat cagctatcat tgatctatga
     8341 acatttgcat ttttacctat atattgtgga ggcattgcca tagtatttgt atatatcttc
     8401 cacttagggt ctgctaaatc aagtgtttct ggagatttta ttatatccat attagcatcc
     8461 catagacttt gtatagttcc tacatctctc cagtatcctt taaatggata agcatacatt
     8521 ccaacattat cttctaacat tttaggtatt aaattttttc caaaatcatc ataatttatt
     8581 tctggatttt tttctgcttc cttaaaataa tttctcaaca ttttccaatc aaatatgtat
     8641 actcccatag atgccaaatt gctcttaggt tcacttggtt tttcttcaaa ttcatagata
     8701 cttgaatctt catttgtatt cattatccca aatcttgaag cttcatccca aggaacttca
     8761 atcactgcta ttgtagcttt agagcctttt tccttatgaa attttaacat tttgctataa
     8821 tccatcttgt atatatggtc accagataat atcaatacat attctggatt ataggtatct
     8881 acaaagtcca tattttgata tatcgcatgt gctgtaccat tataccaatt tccttctttt
     8941 tcattcataa atggttgtaa aacatagaca ccaccattta ttctgtccaa atcccaatga
     9001 cttcccatgc ctatatgtga atttaatatc aacggtctat attgagttaa aacacctaca
     9061 gtatcaatac cagagtttga acaattgctt aacacaaaat ctataattct atacttacct
     9121 ccaaatgata cagctggttt ggcaattctt tttgtaaaaa cacctaatct tgaaccttgc
     9181 cctcctgcca aaatcatagc taacatctct tttttcattt aatgacactc ccctcatcta
     9241 gtaattaata tttataattg catttttact tttataaact ttatcagtca ataaatgtcg
     9301 tgtataaatg ttgcttaaat aataccttaa taaaaataaa ataatatcaa ctatacaatt
     9361 gatataatgt ataccccata atggacttac cgacgtatac attattttcc ataagcacta
     9421 tagtatttat taatattcaa ttattggtta aaaaataata caaattttat tttataaata
     9481 taaaaacatt ttttataaat cctttgtgtc atatgaacat gcttattttt taatttgtta
     9541 aattcgtaat agcaaaatat aatctaatat ttgttaaata attatccaaa gaaaatcaag
     9601 taattattaa tcaactttat tttttaattg atacttcttt gtctataatt taaacaaaag
     9661 gatataaact tttaaattat ttattagttt tcttagtatt aatgtttata tttttataaa
     9721 tatatattaa taatataaat agactaacta aaaccatgct tatttgctat atgttttata
     9781 ttatattata taacactttt tacattagta aaggataaat tgtataaaga ttctgttaat
     9841 ttatttttat aatttcatct ttctaataaa aacaaagaag aagacttaaa aatttataag
     9901 tcctcttctt ttcaacgtgc atttttgtgc tatatttaat taattcgacc tttaatttcc
     9961 atatccttcc tatgataaca aaactctttt atttttttaa tgattcatta tcatttaaaa
    10021 cttcttttat atcaagtact tctttgttat catcactcat aacttccttt attcctttga
    10081 atgttcctag gaaattaact gcttctgaag gtaaaaccag ttttgttgac ttaccttcag
    10141 ccattttttc aagagcttcc atagatttta atgctagaat attattgtct atatcagcct
    10201 ctttcattgc tgaaaaaact aattttaaac cttctgctgt tgccatttga gttcttttta
    10261 tcatttcagc ttcaccttgt gccttagcaa tagctgtctg tcttatagct tcagcttcac
    10321 cttctgccac taatatagca gattcttttt caccttctgc tacacgtacc atagcttctt
    10381 ttttggcttc tgctgttaat attgcagatt gtttttcacc ttctgcttga agtattgcag
    10441 ctgacttatt accttctgct tgaagtattg cctctcttct ttctctttct gctctcattt
    10501 gtttttccat tgcaacttga atatcctgag gaggcattat attttttaac tctactctat
    10561 ttacttttat accccattta tctgttgctt catcaaggat agttctcatt tttacattta
    10621 ttatatctct tgatgttaat gtttcatcta aatcaagttc accaattata tttcttagtg
    10681 ttgtagctgt taaattttca atagcagcta ttggattagc tatctcaaac acatatctaa
    10741 ctgggtctgt aactttataa tatacaactg tatcaatctg catagttaca ttatctttag
    10801 ttataactgg ttgaggtgga aaatctatta caatttctct aaggtcaatt acatatgcca
    10861 ttttatctaa aaatggtatt aagaaatgta cacctgtttc agctactttt tgaaacttac
    10921 caagtctcat tattatacct actttagatt gttttataac tcttatacaa gttaaactta
    10981 ttgctacgac tactactatt aatacaatac ttaaaacaat tttagtaccc atactataaa
    11041 tcctccttta ttctattggt ttgtcacatt aactgtggcg tctacttttt taacaactaa
    11101 ttttacccct tcaattttta atacttctac tgtagaacct ttttctatct tttcaccatc
    11161 tatagaaata gccgtccatg tttcatgttc aactacaact agacctgtgt tatttggaga
    11221 aatctcttct gtaacaatac cttttttaga catcattgct tgtaaattag tgttagattt
    11281 atagccttta tcttttttta ctattttttt agtagctacg actaacattg ctatagaaat
    11341 tactgcaaat attaaaattt gtaagaaaat actctctata aagctactta aaaatataag
    11401 tattacagct cctacactaa accatatcaa tgttaagctt ggtgttaaca tttctgctat
    11461 tccaaataag actgctacta tcaaccatat taacttcata ctatctaccc tcttttcata
    11521 tgaattataa aaccctatat aaattatatg tttatacaat gtttttgaat ataaatttaa
    11581 attacaaaac aataaaataa attaattaat taattaatag tattatatca acatactttg
    11641 ttaaatttgt tacaaagtag tatcaaatat caccaattat atatccaaca actctttcat
    11701 tgttaatgaa atgttactta ttaaatccgt agcatttacc gtatacattg ctttgctcag
    11761 tttatctcct atatagccat gtatatatgc tccactaact gtagcttcca atatatccat
    11821 accttgacct ataaatgaag taatcattcc aagcaaacaa tcacccattc caccagttgc
    11881 catacagcta tttcctgtag gatttatata tgttttttta ccatctgtta tgacagtttg
    11941 ataacctttt aaaagcacca ccagattata tttttgagca aattcttttg caacatctac
    12001 tctatgttct cttatatacc caattgaatc tcctgtcaac ctggccattt ctcccaaatg
    12061 aggtgtaatt acaaatctat ttttccattc taaaaactta taacatctgt ccttcataac
    12121 gttcaatcca tctgcatcta atactattgg gcaattagaa ttttctacta tcttaagtaa
    12181 tttatcaaat gtttgactat tatctcccat acctggacca aaaccaattg catcactaga
    12241 attaagtaat ttatttaatc tttcttcttc aaaatttaaa gtcattgctt ctgtaagtct
    12301 aatagatacc ttttcttgca catcttcact actaattaat gttacaagtc cactcccact
    12361 cttaacagca gattcagttg ctatgaaact tgcaccataa aatccttttg aacctgcaac
    12421 tatagatact tttccaaaat cacttttaaa accatgctta tctcttcttc taatattatt
    12481 ttttacaaaa gtcttatcag ttatgaactc ttcatcatgg tattttcttg taataaaatc
    12541 tggaacacct atcttttcta caactacatc acctataagt gcgctagtgt catagtttag
    12601 aaaacctctt ttataaaact caaagctaat cgttttgttt gctctaatac aagttcctaa
    12661 tacatttcca ttatcgctat ctatacctga aggaatatct atagaatacg tatttttgct
    12721 attatcgttt actatgtcaa taacttcttt aaaaatacca gttatatcac gttttaatcc
    12781 agtcccaaat atagcatcta ctacaacatc acttttagat actctatctt taaaaattgt
    12841 taaattttta ttttttataa tattttgttt ctcaacttta ataattttat ctacttcatt
    12901 ttcctctcca taattttttt cacttaaatc atttttatta atatttataa tattaattcc
    12961 catatttaaa agtacattgt aatttatttt agagcattca cttagttttt caagattacc
    13021 tactaaaaat acgtttactt cttttccata tgtatttaga tgtcttgcta ttccaagacc
    13081 atctcctcca ttatttccaa caccacatac aactgtataa ctattataca tgtctatatc
    13141 catatttttc attgcagata taaccgcatt ttccatcaat acaatcattg gaatccctac
    13201 ttcttctaca catgcagtat caacatttct gcttaattta gatgtaccta ttagcataaa
    13261 ttatcactcc tataaagtta aagacttctt aaatacttac caaaaatatc tattgaaatc
    13321 tttttaatcc cataaatatc ataaataaaa tcactaaaac taagagtttt gaaataattt
    13381 aaaataacaa aaaattttga attaaaacaa ttatttaatt tattatacca tataa
//
LOCUS       DAJMZY010000110        13412 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.111, whole genome shotgun sequence.
ACCESSION   DAJMZY010000110 DAJMZY010000000
VERSION     DAJMZY010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13412)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13412)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13412
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.111"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            91..324
                     /locus_tag="OE968_003094"
     CDS             91..324
                     /locus_tag="OE968_003094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220353.1"
                     /translation="MAQVRKLNRILTIEECKIDDFLEMGYDLIDETGKVVRYGKSLNV
                     KDLIAENNILRSKVESLEEENKQLKEKNKLTKK"
     gene            334..735
                     /locus_tag="OE968_003095"
     CDS             334..735
                     /locus_tag="OE968_003095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220354.1"
                     /translation="MGNNIIDDIEKRLESFGYILKDGDKWLIDFVREKIENIIKLDCN
                     IKTMPIELKEIEADMIVGEFLFTKKNMGQLDIESINFEAVEKSISEGDTKVDFAIGSG
                     SQTPEQRFDSLIAYLTAYGKNKILTFRCLRW"
     gene            729..1076
                     /locus_tag="OE968_003096"
     CDS             729..1076
                     /locus_tag="OE968_003096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220355.1"
                     /translation="MVSKTRKAIEMLYRYKCTIVEYQPIKDPVTKRTNNKEVIVLENQ
                     PCKLSYKNIVSATEGKLAKLEQTIKLFISPDIEIKAGSKLIINDKEYVRSGESAIYPN
                     HQEIILELFKDKA"
     gene            1076..1501
                     /locus_tag="OE968_003097"
     CDS             1076..1501
                     /locus_tag="OE968_003097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HCP7220356.1"
                     /translation="MARWGSVDFREFKRVCKKMEKLTKIDLDKFCKDAARELAARLLG
                     KVIRRTPVDTGFLRQGWNGVAYARSLPVYKQGNNYIIEVVNPTEYASYVNFGHRTKDG
                     KGWVKGQHFLTISEMELQSQVDKIIEKKLLILLKGVFDA"
     gene            1494..1931
                     /locus_tag="OE968_003098"
     CDS             1494..1931
                     /locus_tag="OE968_003098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220357.1"
                     /translation="MLNNIIDGISVKLDKSFGEKYTIYSEDVEQGINEPCFFIVPLNP
                     SKTPYPSGRELKKNSFDVHYFPRSEAKNFEINEIAEMLLEELEYIEINGDLVRGTNMN
                     FEIIDNVLHFFVDYNYFTIKSNNADKMNTVELFGGLKRGDNFE"
     gene            1924..2100
                     /locus_tag="OE968_003099"
     CDS             1924..2100
                     /locus_tag="OE968_003099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220358.1"
                     /translation="MSKTLSKGTDYKFTKEQIVNSKKYVNRKDLLNAILKENELYSFS
                     EVEEIINNFMKGVS"
     gene            2101..3411
                     /locus_tag="OE968_003100"
     CDS             2101..3411
                     /locus_tag="OE968_003100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail sheath family protein"
                     /protein_id="HCP7220359.1"
                     /translation="MALGGGTFVTQNKILPGAYINFISAKRATSSLSDRGIVAMPLEL
                     DWGIDEEVFQVTSDDFEKYSTKYFGYDYTHEKLKGLRDLFKNIRLGYFYKLNKGVKAS
                     CSIATARCSGIRGNDLKVIVTTNIDDNAKFDVVTLLDNKKVDTQIAKVITELQDNDYV
                     TWKKEATLEATAGLTFTNGTNGEAVTGTEYQAFLDKIESYSFNALGCLATTAEIKSLF
                     VEFTKRMRDKVGAKFQTVLYKKNDADYEGVVSVENKIKDTGLLESSLIYWTTGAIAGC
                     DINKSNTNKRYDGEFDVDVNYTQIHLEEALKTGKFIFHKVGDEVHVLEDINTFVSFTD
                     EKNDDFSSNQSVRVLDQIANDIATLFNTKYLGEVPNDKSGRISFWNDVVKHHEQLQNM
                     RAIEDFKADDVSVEPGSDKKTVVVSDAVKVISAMSKLYMTVSVS"
     gene            3433..3903
                     /locus_tag="OE968_003101"
     CDS             3433..3903
                     /locus_tag="OE968_003101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tube protein"
                     /protein_id="HCP7220360.1"
                     /translation="MAQQIKARDTISASKAECFVTIKGKRYNFMQAINLEAKMEKNKS
                     EIPILGSTTKGNKSTGSKYSGNATFYYNTSIFRELLYEYKETGEDIYFDIQITNEDPT
                     SSVGRQTIILEDCNMDSGIIAKFDADGEYLDEDMDFTFENWKLVEKFNIANGME"
     gene            3956..4213
                     /locus_tag="OE968_003102"
     CDS             3956..4213
                     /locus_tag="OE968_003102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220361.1"
                     /translation="MIKIKDKYEIKDSISFDYSNKRPLEERVSEMYKKAGKYLIDISD
                     KLATDTIDGSSLKPIIIKFEINEAGVATIEKQTKYLVMEVE"
     gene            4218..4658
                     /locus_tag="OE968_003103"
     CDS             4218..4658
                     /locus_tag="OE968_003103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HCP7220362.1"
                     /translation="MGDLNAFLSQNAIKVENRKYVASERFIGEDGKAIEWELKAIDSD
                     RDRQLRKDSTIRVPVLNKKGKATGQYTSETDFNTYTLKLCVETVVFPDLHDAELQNSY
                     GVMGAEELLTTMLTPGEYTDLSSEVGEVNGFDRTFEDKVEEAKN"
     gene            4979..5140
                     /locus_tag="OE968_003104"
     CDS             4979..5140
                     /locus_tag="OE968_003104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220363.1"
                     /translation="MDNFLLSILASLIASLIGYIVCRCIKNVKSHSTRGKSKSGWELG
                     FKIKFRKFK"
     gene            5289..5522
                     /locus_tag="OE968_003105"
     CDS             5289..5522
                     /locus_tag="OE968_003105"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220364.1"
                     /translation="MNKDIELTEKDLYCIARHIQVYVFKKDDEVIKKEDNPCCRCKHK
                     FKYYENSVCIYHCSVFQKLSKITGLKMGFGVKL"
     gene            5582..6109
                     /locus_tag="OE968_003106"
     CDS             5582..6109
                     /locus_tag="OE968_003106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4352 domain-containing protein"
                     /protein_id="HCP7220365.1"
                     /translation="MREGKRRRGCLFWFIIIIIFSGVVGAIAGNSTNNGSTEKQKEDL
                     TKYIGEEGNIGDLKLTVNSISKASEIPVASGYLAYTPDSGKYGIINLTIKNQTKESQS
                     FMLNSFTLIGPDNSKYVPSLLIDVGNKYITMDTVNPNLDVTGNIAFEIPKDLLVSDCK
                     LKYSGSEQEFILKEK"
     gene            6232..6810
                     /locus_tag="OE968_003107"
     CDS             6232..6810
                     /locus_tag="OE968_003107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HCP7220366.1"
                     /translation="MLGGNVMFCSNCGAEITGIGKFCSSCGVAVETEIIEDNNIKSND
                     LIVDANGIEINMTEIYRKYRKEKVNAIKNVMEISGLNIKEAKKIVDFSFEELKINFID
                     DTMSNSEKEKIIQNQNRKNNIEKAQQESVACCPKCGSTSLTAQKKGFGIGKAMVGASL
                     TGGIGLVAGNLGAKKVRVTCLNCGKQFWAGKK"
     gene            6888..9176
                     /locus_tag="OE968_003108"
     CDS             6888..9176
                     /locus_tag="OE968_003108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HCP7220367.1"
                     /translation="MATIQTSIRIFDGMTPAFRHMTTAMNIVLSSFEQLQRTSSNAVN
                     ANSIIRAREELARAEAGFDRLERQIRESDNQQRKLNEDINKGASSTDRLVGSAKKLAA
                     TYLGIRTLGGLGNLSDQMTSTNARLGMINDGQQSDAGLNKMIFQSAERSRASYLDTAQ
                     IVSRIGMNAGKAFSSTKEIVGFAEQLNKKFVIAGASTEEMNSALLQLTQGLSSGVLRG
                     EELNAVFESAPNIIQSIADYLDVDIGKIRGMASEGMLTADIVKNSLLAAAEQTNAEFE
                     KMPYTFSQIWTSIKNNAIMIFGVIQKKIEQSMSSKGFRTFIDNFINSLYVLGNVAYNI
                     FNEIISILGSPFFQAFVNAIIVGVSLIVQALGWIITQALNIANVFAQNWSIIAPIVLG
                     VAAAMLVYNNALLLSIANKVKDIALSAKSLVMSFAHIVAESYRAAALVATTIAQDGLN
                     AAMAACPITWILYGIIAIVVAFFVAIAIFNHFAGTSVSAIGVVAGAISVAASFIGNLF
                     IATGNLIIDIVALIYNTLAGFAEFFANFLDDPIGSVIRAVSGMANAVLGIIRSIASAF
                     DTVFGSNLADAVSGWQDKLQGWTDKVAGEAKIKVKRMDPNKLHFDRFNYGKAWDAGYK
                     WGDKLETNIKDKFDISKMAEDAKKKLGLDDLWDKKYGLGDGFGSAGLNSPLNDAAKGA
                     KDTAGNTAKMAKTMDKSQEDLKYLRDIAEQETINRFTGVNIKIDMNNTNNISKDNDLD
                     GIVNVLTEKLNDAMAVSAEGIV"
     gene            9193..9894
                     /locus_tag="OE968_003109"
     CDS             9193..9894
                     /locus_tag="OE968_003109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HCP7220368.1"
                     /translation="MAYDFYLDGVQLPIAPPKLEVKVTNKNKTVDLINVGEVNILKKE
                     GLSEISFEAEFTHNKLPFYRGTFRDVQFFLSKLELLKTDCKPFQFIVSRELGNKVLFN
                     TNIKVSLEEYAISEDADNGSDTKVAIKLKQYRDYSTKKLVPATPEKTNYGRTPPPVMK
                     PKEFRPDSSNKPNGKTYTVKAGDSLWAICQKQLGNGSLYKKVYELNKTMMDKANKGKK
                     LSKYTIYKGQVLRLV"
     gene            9887..11857
                     /locus_tag="OE968_003110"
     CDS             9887..11857
                     /locus_tag="OE968_003110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HCP7220369.1"
                     /translation="MSDDLVLANDRDIRLVIAHWEDFYEPVVLDGITWEIERRGTPSK
                     LEFTIVMDDILEFCEGNSVRLYYKGVGIFYGYIFQKKRDKENHIKIVAYDQLRYFKNK
                     DTYVYSNKTASELVKMLAKDFKLKYNVIEDTKYKISRVEENKTLFDMVLTALDDTLRE
                     KKEMYVLYDDFGRITLKNVASMKLDTVMNNDVIEDFDYNSSIDSDTYTKIKLVRDNEE
                     TGKRDVYIAQDSTHMRSWGILQLFDTVDKNMSEAEIKQKCDILLKLYNKKTKSLSLKN
                     VLGDIRVRAGCLVPVFLSLGDIDLQNYMLVEKVKHTFENNSHFMDLTLVDGDEFASYS
                     SSSYSSGNTNNKNEKQNGPAQSTTSKEDTDMANKINKLLKGKLSNTGNIFVKYSNAYK
                     VNPALMAAISMHESARGTSNIANTKNNFFGMKKNGDYMSFSSVDEGIKRGISNLSRNY
                     IHIGRKTLESIRNKYSSSSDKEWVKCVGAFYKQITGSTYNSNSAGTGVGSNEEAEKNL
                     KDLTYQVQNNNSNTSTNNNNKVSKVIQEAKNQLGKPYKWGGNGPKSFDCSGLMVWAFK
                     RGAGINLKRVSADQSKDSRGKLLCNINDVKAGDLVFFAYNKGKGNVHHVGLYIGNDQY
                     IHAPQTGDVVKISSLSGRQKKKHDFARARRFF"
     gene            11871..12131
                     /locus_tag="OE968_003111"
     CDS             11871..12131
                     /locus_tag="OE968_003111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2577 domain-containing protein"
                     /protein_id="HCP7220370.1"
                     /translation="MSQELLQIIKKAAMDAVETSNPMQIAFGTIESVNPLIVKIEQKL
                     SIGEIFLIQTDTFKRYTDKKIGDKLVLIRMQGGQQYLILDRM"
     gene            12136..12555
                     /locus_tag="OE968_003112"
     CDS             12136..12555
                     /locus_tag="OE968_003112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2634 domain-containing protein"
                     /protein_id="HCP7220371.1"
                     /translation="MLPTDNIDYDIEDVSIINFDVRQEPSKTFKLNIEKNRVDGICDD
                     VEALKQTIFLILNTERYEHLIYSRNYGVELNDLIGEPISYVIPELERRITEALIQDDR
                     IENIDNFEFQNIKGKVQCRFSVHTKYGNIKAEKVVSV"
     gene            12568..>13412
                     /locus_tag="OE968_003113"
     CDS             12568..>13412
                     /locus_tag="OE968_003113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate J/gp47 family protein"
                     /protein_id="HCP7220372.1"
                     /translation="MTFENIIKRMLDSVPDTFDKREGSIIYNALAPVAIELTETYIAM
                     DELLDQTFVDTASYYYLEKRCKERGITPLEATNTIAKGVFNIDIPIDSRFNLGEYNYV
                     AIERISEGIYKMKCETAGPIFELGQLIPIEYIDKLETAELTEILINGEDEESEDSLRQ
                     RYYDSLNSQSFGGNMQNYKDEVNKIQDVGGVKVYPVWNGGGTVKLVIINSNFKVPSSD
                     LVNLVQEEIDPLQNQGEGLGLAPIGHRVTVEGVTSTTINISAEITYKSGYTWENIKLI
                     AEEVI"
BASE COUNT         5334 a         1454 c         2663 g         3961 t
ORIGIN      
        1 cttctacttt gaagaaagtt ttgaggatgt atttatatta aataaaaaag ctgatgcaat
       61 acaatttgtt gttgaaggag ctggagcata atggcacaag taaggaaatt aaatagaata
      121 ttaaccatag aagagtgtaa aatagatgat ttcttagaga tgggatatga tttgatagat
      181 gaaactggta aggtagtaag gtatggcaag tcattaaatg taaaagattt aatagctgaa
      241 aataatattt taaggtcaaa agttgagtct ttagaagaag aaaataagca gcttaaagag
      301 aaaaataaac ttactaaaaa gtaggtgaaa attatgggaa ataatataat tgatgatata
      361 gaaaaaagac ttgaaagttt tggatatata ttaaaagatg gggataagtg gttaatagat
      421 tttgtaagag aaaaaataga aaatattatt aaactagatt gtaatataaa aactatgcca
      481 attgaattga aagaaattga agctgatatg atagttggag agttcttatt taccaagaaa
      541 aatatggggc aattagatat agaaagcatt aactttgaag ctgtagaaaa gtctatatca
      601 gaaggtgata caaaggtaga tttcgctata ggaagtggct ctcaaacacc agaacaacgc
      661 tttgatagct taatagctta tcttactgct tatggtaaga ataagatatt aacctttagg
      721 tgcttaagat ggtaagtaaa actagaaaag caatagaaat gttatataga tataaatgta
      781 ctatagttga gtatcagcca atcaaagacc ctgtaacaaa acgaactaac aataaagaag
      841 tgattgtatt agaaaatcaa ccatgcaagc tttcatataa aaatatagtt tctgctacag
      901 aaggaaaatt agctaagcta gagcaaacta ttaaactctt tatatctcca gatatagaaa
      961 ttaaagcagg ttcaaaactt attataaatg ataaagagta tgtaagaagt ggagaatcag
     1021 ctatatatcc aaatcatcaa gaaataatac ttgagttatt taaggataaa gcataatggc
     1081 tagatggggc agtgttgatt ttagagagtt taaaagagtt tgtaaaaaga tggagaagct
     1141 tacaaagatt gatttagata agttttgcaa agatgcagca agagaattag cagcaagact
     1201 cttaggaaaa gtaattagaa ggacaccagt tgatacagga ttcttaagac aaggatggaa
     1261 tggagtggct tatgctaggt cgcttcctgt gtataaacaa ggaaataatt atattataga
     1321 ggttgttaat ccgactgaat atgcaagtta tgtaaatttc gggcatagaa ctaaagatgg
     1381 aaaaggttgg gttaaaggac aacatttctt aacaatttca gagatggaac tacaaagcca
     1441 agttgataag attatagaga aaaagttatt aatattactt aaaggagtat ttgatgctta
     1501 ataatattat agatggaata tcagtaaagt tagataaatc atttggagaa aaatatacaa
     1561 tttatagtga ggatgtagag caaggtatta atgaaccttg tttttttatt gttcctttaa
     1621 atccaagcaa gacaccatat ccaagcggga gagaattaaa gaaaaattct tttgatgtac
     1681 attatttccc tcgttcagaa gctaagaatt ttgaaataaa tgagatagct gagatgttac
     1741 tggaagaatt agagtatata gaaatcaatg gagatttagt tagaggcaca aatatgaatt
     1801 ttgaaattat agacaatgtt cttcacttct ttgttgatta taactacttc actataaaga
     1861 gtaataatgc agataaaatg aatacagtag agttattcgg tggtttgaag agaggtgata
     1921 attttgagta agacattaag caaaggaacc gattacaagt ttactaagga gcagatagtt
     1981 aattctaaga agtatgtaaa tagaaaagac ttattaaatg caattttaaa agaaaatgag
     2041 ttatattcct tctcagaagt agaggaaata ataaataatt ttatgaaagg agtgagttag
     2101 atggctttag gtggaggaac attcgtaacg caaaataaaa tacttcctgg tgcatatata
     2161 aattttatct cagctaagag ggcaaccagt tcattatcag atagaggtat tgttgcaatg
     2221 cctttagagt tagattgggg tatagatgaa gaagtattcc aagtaaccag tgatgatttt
     2281 gagaagtatt caactaagta ttttggatat gattatacac atgagaagtt gaaaggtttg
     2341 agagatttat ttaaaaatat aaggctagga tatttctata aattaaataa aggtgttaaa
     2401 gctagttgta gtattgctac agctagatgc agtggtataa gaggtaatga cttaaaagtt
     2461 atagtaacaa caaatataga tgataatgct aaatttgatg ttgtaacact tttagataat
     2521 aagaaagttg atactcaaat agctaaagtt attacagaac tgcaagataa tgattatgtc
     2581 acttggaaga aggaagcaac attagaggct acagcaggat taacttttac taatggaact
     2641 aatggtgaag ctgtgacagg aacagagtat caagcttttc ttgataagat agaaagttac
     2701 tcatttaatg cactaggatg tttggctaca acagcagaga ttaaaagttt gtttgtagag
     2761 tttactaaga gaatgagaga caaagttggg gctaagtttc aaactgtatt atataaaaag
     2821 aatgatgcag attatgaagg tgtagtatct gttgaaaata agattaaaga tactggatta
     2881 ttagaatcta gcttaattta ctggactact ggagctatag caggatgcga tataaataaa
     2941 tctaatacta acaagcgata tgatggtgaa tttgatgtag atgttaatta cactcaaata
     3001 catttagaag aagctttaaa aactggtaag tttatatttc ataaggttgg agatgaagtt
     3061 catgtattag aggatataaa tacttttgtt agttttacag atgaaaagaa tgacgacttt
     3121 tcaagtaatc aaagtgttag agtacttgac cagattgcta atgatatagc gactttattt
     3181 aatacaaagt acttgggtga agtaccaaat gataaatctg gtcgtatctc gttttggaat
     3241 gatgtagtta agcatcatga acaactgcaa aatatgagag caatagaaga tttcaaagct
     3301 gatgatgttt ctgtagaacc tggaagcgac aagaagactg ttgtagtaag tgatgctgta
     3361 aaagttatta gtgctatgag taagctttat atgactgttt cagttagtta acaataagaa
     3421 aggagaataa taatggcaca acaaataaaa gcaagagata caataagtgc atctaaggca
     3481 gagtgttttg taactataaa aggtaaaaga tataatttta tgcaagctat taacttagaa
     3541 gctaaaatgg aaaagaataa gagtgagata cctatattag gtagtactac aaaaggaaat
     3601 aaatcaacag gaagtaaata ttcaggaaat gcaacatttt attataatac ctctatattt
     3661 agagaattgt tgtatgagta taaagaaact ggtgaggata tttacttcga tatacaaatt
     3721 accaatgaag acccaacaag ttcagtgggt cgtcaaacta taatactgga agattgcaat
     3781 atggactcag gcataattgc taaatttgat gctgatgggg agtatttaga tgaagatatg
     3841 gattttactt ttgagaattg gaaattagtt gagaaattta atatagcaaa tggtatggag
     3901 taaaatacac atttatgatt tatgtatgtg tattttttat ttataagaat aggagatgat
     3961 taaaattaag gataaatatg agataaaaga ttcaatttct tttgattata gcaataaaag
     4021 acctttggaa gaacgtgtca gcgagatgta taaaaaggca ggaaaatatc ttatagatat
     4081 ttcagataag ttagcaacag atacaattga tggttcgtca ttaaagccaa taatcataaa
     4141 atttgaaata aatgaagctg gtgttgcaac aatagaaaaa caaacaaaat atttggtgat
     4201 ggaggtagaa taagaatatg ggagatttaa acgctttttt aagtcaaaat gcaataaaag
     4261 tagagaatag aaagtatgtg gcaagtgaaa ggtttatagg agaagatgga aaagcaatcg
     4321 aatgggaact taaagcaata gattcagata gagatagaca attaagaaaa gattcaacta
     4381 taagagtacc tgtactaaat aaaaaaggga aagcaacagg gcaatacact agtgaaacag
     4441 attttaatac ttatactttg aaactgtgtg tagaaactgt agtatttcca gatttacatg
     4501 atgcagaact tcaaaatagc tatggtgtaa tgggagcaga ggaactatta acaacaatgt
     4561 taactcctgg tgaatacaca gacctttcaa gtgaggtagg agaagtgaat ggttttgata
     4621 ggacttttga agataaagta gaagaagcaa aaaactaatt gaaggaggcg attatgatgc
     4681 tagtgtagct cattattgcc ttcataaatt caaatggaaa ccacatgaat atacagattt
     4741 accagacttc gagagggcat ttgttgctgc ttctatagat attaaagtag aagaagaaat
     4801 aaaagaagaa aaaaagattg ctaaagaagc tagaagaagt agaagaagat aaaatatagg
     4861 taaaatatgt aagaattata tgttataata attgtagcaa gaagatgtaa tctacaattt
     4921 atagagtgga gttcatactg ggataaaacc tacttcctaa tgaaaggagg tgggaagtat
     4981 ggacaatttt ttacttagta tattagctag cttgatagct agtttaattg gatatatcgt
     5041 ttgtagatgt atcaaaaacg taaaaagcca ctctactcgt ggcaagagta aaagtggctg
     5101 ggaacttggt tttaaaataa agttccgcaa atttaaataa tttatatttt ttaaaattat
     5161 gaacttcact ctaccgctaa atagattgta gttcttcttg cctttattat accacaaatt
     5221 agaaaaaata tgcaaagtac ttgttttaat agtaagtact ttttttatgt gaaaaagaag
     5281 gtgattgaat gaataaagat atagaactta cagaaaaaga tttatattgt attgctagac
     5341 atattcaagt gtatgtgttt aaaaaagatg atgaggtcat aaaaaaggaa gataatccat
     5401 gttgcagatg caagcataaa tttaagtatt atgagaatag tgtatgtatc tatcattgtt
     5461 cagtatttca gaagttatct aaaattacag gtcttaaaat gggttttgga gtcaaactat
     5521 aatgtaaaaa ttttgaatat atagtataat attcttataa aatataattt agggggatat
     5581 tatgagagaa ggaaagagaa gaagaggatg tctattttgg tttatcatta ttattatatt
     5641 ttctggggtt gttggagcaa tagcagggaa cagtactaat aatggaagca ctgaaaaaca
     5701 aaaagaagat ttaactaaat atattggtga agaaggtaat ataggagatt taaaattaac
     5761 tgttaatagt atttcaaaag ctagtgaaat accagtagct tctggttatt tggcgtacac
     5821 tccagatagt ggcaaatatg gtattataaa tttaacaata aaaaatcaaa ctaaggaaag
     5881 ccaatctttt atgctaaatt cattcacatt aataggacca gataattcaa aatatgttcc
     5941 atctttattg attgatgtag gaaataaata tataactatg gatactgtaa atcctaattt
     6001 agatgtaaca ggtaatattg catttgaaat tcctaaggat ttactagttt ctgattgtaa
     6061 actaaaatat agtggttcag agcaagaatt tatattaaaa gaaaaataat atatagattt
     6121 aaaatcaaaa atactaaaaa cacttactaa tgtaggtgtt tttttaatga aaggatgtga
     6181 tgataatgta aaaattttac taatatagta taatattctt ataaaattat tatactgggg
     6241 ggaaatgtta tgttttgttc aaattgtggt gcagaaatca caggcatagg caagttttgt
     6301 tcaagttgtg gggttgctgt agaaactgaa attattgaag ataataatat taaatcaaat
     6361 gacttaatcg ttgatgctaa tggaatagaa ataaatatga ctgaaattta tagaaaatat
     6421 agaaaagaaa aagtaaacgc aataaaaaat gtaatggaaa taagtggttt gaatataaag
     6481 gaagcaaaaa aaatagtgga tttttctttt gaagaattaa aaattaattt tattgatgat
     6541 actatgagta attcagaaaa ggaaaaaata atacaaaatc aaaatagaaa aaataatatt
     6601 gaaaaagctc aacaagaatc agttgcttgt tgccctaagt gtggttcaac atccttgaca
     6661 gctcaaaaaa aaggttttgg tatagggaaa gcaatggtag gagctagtct aactggtggt
     6721 ataggtttag tagctggaaa tttaggagca aagaaagtta gagttacatg cttgaattgt
     6781 gggaagcagt tttgggcagg caaaaaatag atgtattaat tataaaaaca cttactaatt
     6841 tagtaagtgt ttttattatc taaattaaca gaaaggagag tgaaaaaatg gctacaatac
     6901 agacatcaat tcgcatattt gatggaatga cacctgcgtt tcggcatatg acaactgcta
     6961 tgaacatagt actgagttca tttgagcaat tacaaagaac ttctagtaat gcagtaaatg
     7021 ctaatagcat aataagagct agagaagaac tagcaagagc agaagctgga tttgatagat
     7081 tagaacgaca aataagagaa tcagataatc aacagcgaaa acttaatgag gatataaata
     7141 agggtgcaag ttctacagat agattagttg gaagtgcaaa gaagctagca gcaacttatt
     7201 taggtataag aacattagga ggtctaggaa atttaagcga ccagatgaca agtactaatg
     7261 cgagacttgg catgataaat gatgggcaac aatcagatgc tggacttaat aaaatgatat
     7321 ttcaatcagc tgaaaggtca agagcatctt acttagatac tgcacaaata gtgagtcgta
     7381 taggcatgaa cgcaggaaag gcgtttagca gtacaaaaga aattgtaggt tttgcagagc
     7441 aattaaacaa aaaatttgta atagcaggcg caagtactga ggaaatgaac tcggcattgt
     7501 tacagctaac ccaagggttg agttctggcg tattaagagg tgaggaactg aatgctgtgt
     7561 ttgagtcagc acctaacatc atccaatcga ttgcagatta tttggacgtg gacataggaa
     7621 aaataagagg aatggcatca gagggaatgt taacagcaga tattgtaaaa aactcattac
     7681 ttgcagcagc agagcagacc aatgcagagt ttgaaaaaat gccttacaca ttttctcaaa
     7741 tttggacttc aattaaaaat aatgcaatca tgatatttgg tgttatacag aaaaaaattg
     7801 aacagtctat gtctagtaag ggatttcgaa cctttataga taattttata aactctttgt
     7861 atgtacttgg aaatgttgct tataacattt ttaatgaaat tataagtata ttagggagcc
     7921 cgttttttca agcatttgta aatgcgatta ttgtaggtgt tagtttaata gtgcaggcac
     7981 taggttggat aataacacag gcattaaata ttgctaatgt gtttgctcag aactggagta
     8041 ttattgcacc aatagtactt ggagttgcgg ctgctatgtt agtgtataac aatgcgttat
     8101 tacttagtat tgcgaataaa gttaaagata ttgcactatc tgccaaatct ttagtcatga
     8161 gctttgcaca tatagtagca gagtcttata gagcagcagc tttagtagca actacaatag
     8221 cacaagacgg attaaatgca gcaatggcag cttgtcctat tacttggatt ttatatggaa
     8281 ttatagctat agttgttgca ttttttgtag ctatagcaat atttaatcac ttcgcaggca
     8341 ctagtgtatc tgctataggt gtagttgcag gtgcaatatc agttgcagcc tctttcatag
     8401 gaaacttatt tattgcaaca ggaaatttaa ttatagatat tgtagcttta atatacaata
     8461 ctttagcagg ctttgcagag ttctttgcta attttttaga cgacccaatt ggctctgtta
     8521 taagagcagt atccggaatg gctaatgctg tattaggcat tataagaagt atcgcaagtg
     8581 catttgatac cgtgtttggt tcaaacttgg cagatgcagt aagtggatgg caagataaat
     8641 tgcaaggttg gactgataaa gtagcaggag aagctaaaat aaaagttaaa agaatggacc
     8701 ctaataaact gcattttgac agatttaatt atggaaaagc atgggacgca ggatataaat
     8761 ggggagataa gttagaaact aatataaaag ataaatttga tattagcaaa atggcagaag
     8821 atgcaaagaa aaaattagga ttggatgatt tatgggataa aaaatatgga ttaggagatg
     8881 gatttggttc agcaggatta aactctcctc tcaatgatgc agcaaaagga gcaaaagaca
     8941 ctgcgggaaa tacagcaaag atggctaaaa caatggataa aagccaagaa gacttaaaat
     9001 acttaagaga catagcagaa caggaaacaa tcaatagatt tacaggagta aacataaaaa
     9061 ttgatatgaa caacacaaac aacataagta aagataatga cttagatgga atagttaatg
     9121 ttctaactga aaagttaaat gatgcaatgg ctgtttcagc cgaaggaata gtttaggaag
     9181 gagagtgaga aaatggctta tgatttttac ctagatggag tacaactacc aatcgcacca
     9241 ccaaagcttg aagtcaaagt gacaaataaa aacaagacag ttgatttaat aaatgttgga
     9301 gaagtaaata tattaaaaaa agaaggatta tctgaaataa gttttgaagc agaatttaca
     9361 cataataaac taccatttta tcgtggaact tttagggatg ttcaattctt tttaagtaaa
     9421 ctggaactac taaaaactga ttgtaagcca tttcaattta ttgtatcgag ggaattaggt
     9481 aataaagtac tatttaacac taatataaaa gtatctcttg aagagtatgc tatttcagaa
     9541 gatgcagata atggctcaga tacaaaagtt gcaataaaat taaaacaata tagagattac
     9601 tcaactaaaa agttagttcc tgcaactcct gaaaagacaa actatggtag gactccccct
     9661 ccagtcatga aaccaaaaga atttagacca gattcatcca ataagccaaa tggtaaaaca
     9721 tatacagtaa aagcagggga ttctctttgg gcaatttgtc aaaagcaatt aggaaatggt
     9781 tcgttataca agaaagtata tgagttaaat aaaacaatga tggataaagc taacaaggga
     9841 aaaaaattaa gtaaatacac catctataaa gggcaggtgt tgaggcttgt ctgatgattt
     9901 agttctggcg aatgatagag atataaggct agttattgca cattgggaag atttctacga
     9961 acctgtagtt ttggatggta tcacatggga aatagagaga cgaggaacac catctaaact
    10021 tgaatttaca atagtcatgg atgatatatt agagttttgt gaaggtaact ctgtaagact
    10081 atattacaaa ggtgtaggta tattctatgg atatatattt cagaaaaaga gagataaaga
    10141 aaatcatatc aagatagttg cttatgacca gctaagatat tttaagaata aagatactta
    10201 tgtatatagt aataaaacag caagtgaact tgtaaagatg ttggctaagg attttaaatt
    10261 aaaatacaat gtcatagaag atacaaaata taaaatatcg agagttgaag aaaataaaac
    10321 actctttgat atggtcttaa ctgcactaga tgatactcta agagagaaaa aggaaatgta
    10381 tgttttatat gatgattttg gaagaataac attaaagaat gttgcttcta tgaaacttga
    10441 tacggttatg aacaatgatg taattgagga ctttgactac aattcttcta ttgatagtga
    10501 tacttacaca aagattaaac ttgtgagaga taatgaagaa acaggaaaaa gagatgtgta
    10561 tattgctcaa gactcaacgc atatgaggag ttggggaata ctacaactat ttgatacagt
    10621 tgataaaaat atgagtgaag cagagataaa acaaaaatgt gatatactcc taaaactata
    10681 taataagaaa actaagtcat taagtttaaa aaatgtgtta ggagatatta gagtaagagc
    10741 aggttgttta gtacctgttt ttttgtcgtt aggagatatt gatttacaaa attatatgtt
    10801 agttgagaaa gtaaaacata catttgaaaa taacagtcat tttatggacc taactttggt
    10861 tgatggagac gaatttgctt cttattcttc atcaagttat agtagtggaa atactaataa
    10921 taaaaatgag aaacaaaatg gtcctgcaca aagtactaca agtaaagaag atactgatat
    10981 ggctaataag attaataaac tacttaaagg taaattatca aatacaggaa atatatttgt
    11041 taaatattca aatgcttata aagttaatcc agcactcatg gctgctatat ctatgcacga
    11101 atcagctaga gggacttcaa atattgcaaa tactaaaaat aatttctttg gaatgaaaaa
    11161 aaatggagat tacatgagtt tttctagtgt agacgaagga ataaaaagag gtataagtaa
    11221 tttatcaaga aactatatcc atataggacg aaaaacttta gaaagcatca gaaataaata
    11281 ttcttctagt tcagacaaag aatgggtaaa atgtgtaggt gcattttata agcaaataac
    11341 aggaagtact tataattcta atagtgcagg cacaggagtt ggaagtaatg aagaagcaga
    11401 aaagaattta aaagatttaa cttatcaagt tcaaaacaat aattctaata catcaacaaa
    11461 caataataat aaagtaagta aagttattca agaagcaaaa aatcaacttg gcaagcctta
    11521 caaatggggt ggtaatggtc caaagagttt tgactgtagt ggtcttatgg tgtgggcatt
    11581 taaaagaggt gcaggaataa atctcaaaag agtttcagca gaccaatcaa aagatagtag
    11641 aggaaaacta ttatgtaaca taaatgatgt aaaagctggt gatttagtat tctttgcata
    11701 caacaaagga aaaggaaatg tacatcatgt tggactatat ataggaaatg accaatatat
    11761 tcatgctcca caaactggtg acgtagtaaa aataagtagt ttaagtggta gacaaaagaa
    11821 aaagcatgat tttgcaagag ctagaagatt cttttaagtg aggtgataaa gtgtcacaag
    11881 aattattgca aataattaag aaggctgcaa tggatgcagt agaaacaagc aatccaatgc
    11941 aaattgcatt tggaactata gaaagtgtta atcctttgat agttaagata gaacaaaaac
    12001 tatctattgg tgaaattttt ctaatacaaa cagatacatt taaaagatat acagataaaa
    12061 agataggaga taaattagtc ttaattagga tgcaaggagg gcaacaatac ttgattttag
    12121 ataggatgtg atgaaatgtt accaacagat aacattgact atgatataga agatgtatcg
    12181 ataattaatt ttgatgttag acaagaacca agtaagacgt ttaaattgaa tatagagaaa
    12241 aatagagtag atggtatttg tgatgatgta gaagcattaa aacaaaccat ttttttaatt
    12301 ttaaatactg aaaggtatga gcaccttatt tattctagaa attatggtgt tgaattaaat
    12361 gatttaattg gagaacctat ttcatatgta atacccgaac ttgaaagaag gataacagaa
    12421 gcactaattc aagatgatag gattgaaaat atagataatt ttgagtttca aaatataaag
    12481 ggtaaagtac aatgtagatt ttcagttcat acaaaatatg gaaatataaa agcagagaag
    12541 gtggtgagtg tataattgtt tgagttaatg acatttgaaa atataattaa aagaatgtta
    12601 gatagtgtac cagatacttt tgataaaagg gaaggttcta taatatataa tgctcttgct
    12661 cctgttgcta tagaacttac agaaacatac attgctatgg atgaattact agaccaaaca
    12721 ttcgtagata ctgctagtta ttattattta gagaagagat gtaaagagag aggtattaca
    12781 ccacttgaag ccactaatac aattgcaaaa ggagttttta acatagatat tcctattgat
    12841 tctaggttta atctaggaga atataactat gtagcaattg agagaatatc tgaaggtata
    12901 tataagatga aatgtgagac tgcgggacct atttttgagt tggggcaact aatacctatc
    12961 gaatatatag acaaattaga aacagcagaa ctgacagaaa tactgataaa tggagaagat
    13021 gaagaatcag aggacagtct aaggcaacga tattatgata gtttaaattc acaatcattt
    13081 ggtggaaata tgcaaaatta taaagatgaa gttaacaaaa tacaagatgt tggaggagtt
    13141 aaagtatatc cagtttggaa cggtggaggt actgttaagt tagtaataat taattctaac
    13201 ttcaaagttc catctagtga tttagttaat ttagttcaag aagaaattga ccctctacaa
    13261 aaccaaggag aaggccttgg tttagcgcca ataggtcata gagtcaccgt tgaaggagtt
    13321 acaagtacaa ctataaatat atcagcagag ataacataca agagtggtta cacttgggag
    13381 aatataaaat taattgcaga agaagtaatt ga
//
LOCUS       DAJMZY010000111        13384 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.112, whole genome shotgun sequence.
ACCESSION   DAJMZY010000111 DAJMZY010000000
VERSION     DAJMZY010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13384)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13384)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13384
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.112"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            complement(73..783)
                     /locus_tag="OE968_003114"
     CDS             complement(73..783)
                     /locus_tag="OE968_003114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCP7220373.1"
                     /translation="MTSICICDDEKQQRNMLNKIITREMDLWGYPYQIKEYSNGESLV
                     YNLEHENYYIDIIFLDIELGKSNGVDIAKTIRKHSKDTIIIFVTGFSDYVFHGYDVGA
                     LNYILKPYKTEKICKVLKEALKKLEQWKENFITVQIGTNLCKINTKDILYFKSELRKL
                     TVVTFDKTLEYYGKLNDMETVLPSNFIRTHQRYIVNLNHVDSITQTYAKVQNEKIPIS
                     RKKYQEVVGKFTRYMLEP"
     gene            complement(1167..3278)
                     /locus_tag="OE968_003115"
     CDS             complement(1167..3278)
                     /locus_tag="OE968_003115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCP7220374.1"
                     /translation="MTINKLYSKLRAYNWKNYTTLFFCIILSVVLVTSYALIYFSPTI
                     QNILPTGGDSRKQATMIFSVAILGCAVFTTYASSLFLKFKSKEIGIFMALGTDKKKLK
                     KLLFSEILLISIVCCFLGLILSIPVSFGIWKIFQLVIIDTREMTYHFGTQGFIYGFIF
                     SVFVTLCIFILSVKFINRTNIIDILNDQRISEPIQDVKDWYGILGIIFIILGIFLGYL
                     VPSLTINKLNYKLPSIWSFTYLLSLIGIYMIMTYIVVHAKRGKHPEKYYKNIISTSMM
                     RFMGRQTVKNMCVISFLIAGALFAVFYVPNMVTGIYDTLKNNPIDYTFTYNQRDKQVS
                     KKDIEQLADKHNIKIQNYMEIPSIELIVDGVESIYHKDGTIEKVYMKKSSYDMFFNSK
                     DFSKLIGKPITIKNGEYLAVVNKGNENQDYKYTKFISSPVTEKEIPFRYAGKIIFNGS
                     FFQNRSMNAYVLNDEDYKSFTKDLSIKNYNNSILFNVDKDTYAFANDLKKEIIKRTSK
                     EMGMFSGYDEYVKKRYESTGRKYFMDEEYPSGEGHLKLDPNNNQLYLNWKYYPNFKIL
                     QSQDMIKNMAVFLMLFIYVAIICFTAVGIIAYTRGVTIAINHKQVFMDLNRLGANNDY
                     IKFCIRNQLKKVFSYPLIAGSFLIYLFNFMIMLNNDGRIVNSEVNALLINLGFIGICG
                     VYMYLIYLLTYKKFKKIIGIL"
     gene            complement(3268..4020)
                     /locus_tag="OE968_003116"
     CDS             complement(3268..4020)
                     /locus_tag="OE968_003116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCP7220375.1"
                     /translation="MLKVNQLCKSYKTGSKTYPVLKNISFEINKGEFVAIMGSSGSGK
                     TTLLNCISCFIPIDNGEIILGNNNIRNLKEKELSEVRNQQLGFVFQDFMLFDGLSVFE
                     NICVPQIIKGSQVLQMENRAINLCELFGIEHIRKKYPAEISGGEKQRTAVARALMNNP
                     DLILADEPTGNLDSKSCRTVIESFLKAKQELDATILMVTHDSFAASFCDRVIVLKDGI
                     IYKEVVKSNSRHKFLDELLEVLKEMGGAQDDN"
     gene            complement(5286..5462)
                     /locus_tag="OE968_003117"
     CDS             complement(5286..5462)
                     /locus_tag="OE968_003117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220376.1"
                     /translation="MFFTFIGVISAILLLCTIICGLWIKLNNRNNDSNSHFTFSILSI
                     AFSLLIVVAFLVRN"
     gene            complement(5566..6174)
                     /locus_tag="OE968_003118"
     CDS             complement(5566..6174)
                     /locus_tag="OE968_003118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCP7220377.1"
                     /translation="MGKLLRGKIMKADSTKEQLINATIQLLSSHRDVSSITAREIVAK
                     ANVNLAMINYYFKSKEELINISIKKFLKRHMDEYKATHDTKNLAPKQQLREILIAFFD
                     FIGEHSQFIKISVPYILIQEEIVYPFEILPLIKAHYENQNNKKTEAEYRTIAYQITSF
                     IQLLFLRSNAFFKYSGIDILNIEQRNGLIDFQLDLLLVDITK"
     gene            complement(6273..7097)
                     /locus_tag="OE968_003119"
     CDS             complement(6273..7097)
                     /locus_tag="OE968_003119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HCP7220378.1"
                     /translation="MFKIGEVSKLTQISIRMLRYYDELGILKPAEIDKYTGHRLYSVE
                     QISILQRIVLLRDSKFSVAEIANIVHNWNDEFVIKELNRKKNEIQKEINQEQQRINKI
                     DKFIEAINCDKDEIHYNVVFKKIPSYKIISLREIIPDYQSEGILWEKLSKFIKEEHIE
                     VSRQSNNNIAFYHDEEVKDNGVDIEVGMVVKKIGKNKSGFIYRETEEIDMMACTMVYG
                     PYENIAGAYESFCYWLDKNSDYQISGINRQIGHKGEHNEINPENYLTEIQIPLIKV"
     gene            complement(7275..8168)
                     /locus_tag="OE968_003120"
     CDS             complement(7275..8168)
                     /locus_tag="OE968_003120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HCP7220379.1"
                     /translation="MQLYNTPFNTNKHLIYFFTFTLVLNWIFSLTPALLGITNTILGE
                     IIFYLAYTSPAIVGLFFISTIYPQSAKQDFIYRYLSFKEIRIKWILLTILFFALTFIT
                     SLIIGNYFNVKTSDIDWIHIAVFRPSKIAYMLLASFILSILSQEAGWRGYAIDKLLVR
                     FGFIGSSIILGLVCGIWYLGSYFTPNQIPYNLAQYSLFDAFLFIPNIVLLNFIINFVY
                     INTSRSILSAGLVHMMYYFFNIQLLLHYPIKLCVIAQYVQIIFGLIFLVYMISSNKFK
                     QKVNSEIEQIKSDDFEFELDW"
     gene            complement(8425..8862)
                     /locus_tag="OE968_003121"
     CDS             complement(8425..8862)
                     /locus_tag="OE968_003121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family transcriptional regulator
                     DNA-binding domain-containing protein"
                     /protein_id="HCP7220380.1"
                     /translation="MKIHVEQGINCDDIEITIKCSALDNNIEKIISLLSTPLLDIKGK
                     KSGEIYKLNVCDILYFETVGNKTFAYYEDDVFEIDLKIYKLSKLLANTSFSRISKSMI
                     LNMDYIKSIKVISHNRMQATLKNNEKVIINRRYIKNIKEKLNI"
     gene            complement(9119..9268)
                     /locus_tag="OE968_003122"
     CDS             complement(9119..9268)
                     /locus_tag="OE968_003122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvrJ family protein"
                     /protein_id="HCP7220381.1"
                     /translation="MDDSLQLLITNVGFPIALSMYLLVRIEGKLNTLSNSIDTLSKNI
                     LIFKK"
     gene            complement(9281..9511)
                     /locus_tag="OE968_003123"
     CDS             complement(9281..9511)
                     /locus_tag="OE968_003123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2922 domain-containing protein"
                     /protein_id="HCP7220382.1"
                     /translation="MEIKKKLVMSFKNVKDKQVSFSIENPKDDLTEENIKSVMDLIVS
                     KNIFSVGGFDLASVVEAKVVETNTTPYDLVIE"
     gene            complement(10329..10550)
                     /locus_tag="OE968_003124"
     CDS             complement(10329..10550)
                     /locus_tag="OE968_003124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1659 domain-containing protein"
                     /protein_id="HCP7220383.1"
                     /translation="MEVVSTKNLSSIKLKLDAGFDDKGKAVVKSKSFANVKAEALNED
                     VYAVAEAIASLQENPIVDILKLDSTSLSK"
     gene            11130..11387
                     /locus_tag="OE968_003125"
     CDS             11130..11387
                     /locus_tag="OE968_003125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HCP7220384.1"
                     /translation="MKIKVEDIPVQFHAMVEIIGIDKFIEVAKLYGGTNTYIPTYKGL
                     FRYARNRDIVKQFNGVNHNELAIRYNMCVSNIKRILNENNV"
     gene            11856..13094
                     /locus_tag="OE968_003126"
     CDS             11856..13094
                     /locus_tag="OE968_003126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conserved phage C-terminal domain-containing
                     protein"
                     /protein_id="HCP7220385.1"
                     /translation="MNKGFYKLNSVVLNFDIKNDVNKIRFNHYIMRKENIQRLQGTLP
                     NGQFYMTVRRAATDLQLSISTISRLVKEFLDLGIIRLVSKGVKGNRSVYSYVSIEFNG
                     SLFDDSKYMELDCVCNDEFIDNSGIEFDCDSKDNSFNGDINVETVHCINEYLSDDDVE
                     HNYNNFHNKDTIKDKAISNISTIKKYIDESFDKNKSENSNLQQESINFNFNDTCNEID
                     KRTNNSIENNQNKRPMRLSDISLLSDKGMTNKKNYFNHNHGIQKGTKSVTKKKESLNK
                     FNKKNIQQSIINMLNKKSGKNFKIDSPISIKLINERLKEGYVLEDFYKVIEVKVAKWK
                     NTIMEMYIRPETLFSYKFESYVNENISMKSQSNVHPCKEGNSNDSSNYIHSDYTTYDG
                     SVRERKKYENVRYWNPICEI"
BASE COUNT         4949 a         1605 c         1767 g         5063 t
ORIGIN      
        1 acaaaactct aaaaactaag ctttaaaaag ttaagtttca aaaataaaat tctagagatt
       61 gaacttcaaa aattaaggtt ctaacatata ccttgtaaat tttcctacaa cctcttgata
      121 ttttttacgg cttataggaa ttttttcatt ctgaactttg gcataagttt gagttatact
      181 atctacatgg tttagattga caatatacct ttgatgcgta cgtataaaat tagagggaag
      241 aacagtttcc atatcattta attttccgta gtattctaat gttttatcaa aggtaactac
      301 agttaatttt cttagctcac ttttaaagta gaggatatct tttgtattaa ttttacaaag
      361 attagttcca atctgaactg taataaagtt ttctttccat tgttctaatt tttttagtgc
      421 ttcttttaat actttacata ttttttcagt tttataaggt tttaagatgt agttcaaagc
      481 tcctacatca tatccatgaa atacatagtc agaaaaacct gtgacaaaga tgattatagt
      541 atcctttgaa tgttttcgta tagtttttgc tatgtcaacg ccattacttt ttccaagttc
      601 aatatctaaa aaaataatat ctatgtaata attttcgtgt tctagattgt atactagact
      661 ttctccattt gaatattctt ttatttggta ggggtagccc cacaaatcca tttctcttgt
      721 aatgatttta ttcagcatgt ttctttgttg tttttcatca tcacaaatac aaatcgaagt
      781 caatttttta tctcctttca aattttatat ttatatagtt aagtatataa tatattttgc
      841 tacctagata tataaaatga aataacaatt atatccagat agcaaaataa aattttttat
      901 attagtatac ttacacttaa aactattcta ttaaacttat tctgaagtgc taatgatttt
      961 cttattaaaa aatctaacaa tctttcttat tataaaatac aaatgctttt attattataa
     1021 aaagtaatga ttttattact ttaaaaatct aataaccttt cttattataa aacaccaatg
     1081 attttattac tttaaaaatc taataacctt ttttattata aaacaccaat gattttatta
     1141 ctttaaaaat ctaataacct tttttattat aaaataccaa taattttttt gaatttctta
     1201 taagttaata gatatataag gtacatataa accccacaaa tccctataaa acctaagttt
     1261 atcaaaagag cattgacctc actattgacg attctaccat cattatttaa cataatcata
     1321 aaattaaaca gataaattaa aaaacttcct gcaataagag ggtatgaaaa tactttcttt
     1381 aattgatttc taatacagaa ctttatataa tcattgtttg ctcctaatcg atttaaatcc
     1441 ataaagacct gcttgtgatt tatagctata gtaacacccc ttgtatatgc aatgattcct
     1501 actgctgtaa aacatatgat tgccacatat atgaataaca ttaagaagac tgccatgttt
     1561 tttatcatat cttggctttg taaaatttta aagttaggat agtatttcca attaagatac
     1621 aactgattgt tgtttgggtc tagttttaaa tgaccttcac cacttggata ttcttcatcc
     1681 ataaaatatt ttcttccagt tgattcataa cgttttttta cgtattcatc ataaccactg
     1741 aacatgccca tttccttaga tgttcttttt ataatttctt tctttaagtc attggcaaaa
     1801 gcataggtat ctttatctac attaaatagt atagaattat tgtaattttt tatggataaa
     1861 tctttagtaa atgatttata atcctcatca ttaaggacat aggcgttcat acttctattt
     1921 tgaaaaaaag aaccattaaa tattattttt ccagcatatc taaaggggat ttctttttct
     1981 gtgactgggc ttgatataaa tttggtatat ttataatctt gattttcatt tcctttattt
     2041 acaacagcaa gatattcacc attttttata gttattggtt tgccaattag cttggaaaaa
     2101 tctttagaat taaagaacat atcataggag ctttttttca tatatacctt ttcgatagtt
     2161 ccatctttat gatatattga ttctacacca tcaacaatta attctataga aggaatttcc
     2221 atatagtttt gaatttttat attgtgttta tctgctaatt gttcaatatc tttttttgat
     2281 acctgtttat ctctttgatt gtaggtaaaa gtataatcta tagggttatt tttaagagta
     2341 tcatagatac ctgtaaccat attaggaaca tagaatacag caaataatgc tcctgcaatc
     2401 aaaaatgaaa taacacacat gttttttact gtttgtcttc ccataaatct catcatgcta
     2461 gttgatatga tgtttttata gtatttctct ggatgttttc ctcttttagc atgtacaact
     2521 atgtatgtca taatcatata tattccaata agagagagta gataagtaaa gctccatata
     2581 gatggtagtt tataatttaa tttgtttata gttagtgaag gtacgagata tcctagaaaa
     2641 ataccgagta taataaaaat tatacctaat ataccatacc agtcctttac atcctgtatt
     2701 ggttcagata ttctctggtc atttaatata tcaattatat ttgtacgatt aataaatttt
     2761 acagaaagta taaatatgca taatgtcaca aatacactaa atataaatcc atatatgaat
     2821 ccttgagttc caaaatgata tgtcatttct ctggtatcaa taatcactaa ttgaaatatt
     2881 ttccatatac caaaagatac aggaatactt aatataagac ctaaaaaaca gcatactatt
     2941 gaaattaaca atatctctga aaatagaagt ttttttaatt tcttcttatc tgttcctaga
     3001 gccatgaaaa taccaatttc cttgctttta aattttaaaa agagggaaga agcgtatgta
     3061 gtaaagacag cgcatcctaa tatagcaact gagaatatca ttgtagcctg ttttctgcta
     3121 tctccaccag ttggaagtat gttttgtatt gttgggctaa aataaattag agcatatgaa
     3181 gttactaata ccacagaaag tattatacaa aagaataaag ttgtatagtt cttccaatta
     3241 taggctcgaa gtttactgta taatttatta attgtcatct tgagcgcctc ccatttcttt
     3301 taaaacttct agtaattcat ctaggaattt atgtcttgaa tttgatttta caacttcttt
     3361 ataaattatt ccatctttaa gcacaataac tcggtcacag aagcttgctg caaagctatc
     3421 gtgtgtaacc atgagtatag tagcatctaa ttcttgcttt gcttttaaaa atgattcaat
     3481 gactgtacga caagacttac tatcaaggtt accagttggt tcatctgcta atattaaatc
     3541 tgggttgttc atgagtgctc ttgctactgc tgtacgctgt ttttctccac cagatatttc
     3601 ggcagggtat ttttttctga tatgttcaat accaaatagc tcacatagat taattgcacg
     3661 gttttccatt tgtaagactt gactaccttt gataatttgt ggaacacata tattttcaaa
     3721 gacactaaga ccatcaaata gcatgaagtc ttggaataca aatcctagtt gttgatttct
     3781 aacttctgaa agttcctttt cttttaaatt tcttatatta ttatttccaa gaattatttc
     3841 cccattatca attgggataa aacatgaaat acaatttaaa agagtagttt ttccacttcc
     3901 tgatgaaccc atgattgcga caaattctcc tttgttgatt tcaaaagaaa tattttttaa
     3961 tacaggatat gttttactgc ctgttttata tgatttacat aattggttta ctttaagcat
     4021 atatatcatc ctcactttca tttatcttgt aagtcaatga tagcatttga aaggggagga
     4081 gggatatgag ctatattgta atagttggat gtttttttgt aatgtttgaa aatatattgt
     4141 ttggatagtg tgagaggtta ttattatagt taaattgatt atattattgg aggatttaga
     4201 gggttatttt taggtattaa ttgttgtgct aaagtaatat gatgtggaac attgaaggtg
     4261 tagttagaaa agaagtatat agtaaaagta aaaaggttat agaataacga atgttgtatt
     4321 gaaaaaaatg atgtaaataa tgtatagtag ggttaaaaag aaaaaaagaa ttatagagca
     4381 gtaagattat ttaatagaat gtattgtaaa taatttgaaa ggatttaggg gctattaaca
     4441 caatgtaatt gagaaaatat attggagttt tggaaataaa taggttgtta gaaacaattg
     4501 aaatgtataa taaaaaggtt aaaaagtatt attagtatag gtatgataga taattttaga
     4561 aagtggaagt attttagact atgctgaaaa gtgattgata tgattttgag atattaaaat
     4621 attactatat tatagtaaag aagttaaaat aataaaatgt tgtaataata aaggtttgta
     4681 gtataataaa gaactgtaat aaataagact ttgcaatgta atagaaatgc tgtaataata
     4741 aaagtctgta gtataataaa gaactgtaat aaataagact ttgcaatgta atagaaatgc
     4801 tgtaataata aaggtctgta gtatagcaaa gaactgtaat aaataagaga ttgtaataat
     4861 aaaagtctgt agtgtaataa agaactgtaa taaataagac tttacaatgt aatagaaatg
     4921 ctgtaataat aaaggtctgt agtataataa agaactgtaa taaataagac tttacaatat
     4981 aatagaaatg ttgcaataac aaaacaccat aataaataag agtttgcaat ataatagaaa
     5041 cactgcaata aataagagat ttcaatataa taaaagtctg taatataaca aaatcctata
     5101 ataaataaga ttttacaata taataaaaat cctataataa ataggactct gtaatataat
     5161 aaaatgctgt aacaacaaaa cactataata aataagaccc tgtaatataa taaaaatact
     5221 ataatatagt aaaaatcatg caataataaa aatctataat aataaacctc agcataacaa
     5281 agacattaat ttcttactaa aaaggccacc acaattaaca gtgaaaaagc aattgaaagt
     5341 attgaaaaag taaaatgaga attagagtca ttattacgat tattaagttt tatccataaa
     5401 ccacatataa ttgtacacaa caataaaatt gctgatatta ctcctataaa tgtaaaaaac
     5461 attaaaattc ctccccctta tttaatgcaa gtatttttag tcaatgagaa tattttcaaa
     5521 cgttaccata aaataaaaaa atgtacataa aaaattaata tagtattatt ttgtaatatc
     5581 taccaataat aaatctaatt gaaaatctat taaaccattt ctctgttcaa tattaagaat
     5641 atcaatacca ctatacttga aaaaagcatt agaacgaaga aaaagcaact gaataaatga
     5701 agttatttga tacgcaatag ttctgtattc agcttcagtt tttttgttat tctgattttc
     5761 atagtgagcc ttaattaaag gtagtatctc aaatggataa acaatttctt cctgtatcaa
     5821 tatatagggt acagaaatct ttataaattg actatgttca cctataaaat caaaaaatgc
     5881 aattagtatt tcccttaatt gctgtttagg tgctaaattt ttagtatcat gtgtagcctt
     5941 atattcatcc atatgacgct ttaaaaattt tttaatagaa atattaatta actcctcttt
     6001 agatttaaaa taataattaa tcatagctaa attgacattt gctttagcta caatttctct
     6061 agccgtaatg cttgaaacat ctctatgtga agatagtaac tggattgtgg cattaattaa
     6121 ttgttccttt gttgaatctg ctttcataat ttttcccctt aaaagtttcc ccataaaaaa
     6181 attaaacatg tttaacacac gtttagatac tatcatgaaa attttgggat gtcaatgggt
     6241 gattagtact taagtattta agtactaatc tattagactt ttataagggg gatttgaatt
     6301 tctgtaagat aattttcagg atttatttca ttatgttcac ctttatgtcc gatttgtcta
     6361 tttatacctg atatttgata atcactattt ttatctaacc aataacagaa cgattcatat
     6421 gcaccagcta tattttcata tggaccataa accatagtac atgccatcat atcaatttct
     6481 tctgtctcac gatatataaa tccagatttg ttctttccaa tcttctttac aaccattcca
     6541 acttcaatat ctacaccatt atctttgact tcttcatcat ggtaaaaagc tatgttattg
     6601 ttggattgac gtgatacttc tatatgttct tctttgataa atttagatag cttttcccag
     6661 agtatacctt cagattggta gtctggaatt atctctctaa gtgatatgat tttataactt
     6721 ggaatctttt taaagacaac attgtaatga atttcatctt tatcacagtt tatagcttct
     6781 ataaatttat caattttatt tattctttgt tgttcctgat ttatttcctt ttgtatttca
     6841 ttcttttttc tattcaattc tttaattaca aattcatcat tccaattatg tacgatattt
     6901 gctatttctg caacgctaaa ttttgaatct ctcaataata caattctttg tagtattgaa
     6961 atctgttcaa ctgagtataa tctatgacct gtatatttgt ctatttctgc aggttttaaa
     7021 ataccaagtt catcataata acgcaacata cgaatagaaa tttgtgttag ttttgaaacc
     7081 tctcctattt taaacatgaa aatatgacct ccttttcact tataatcagt atatattttg
     7141 tttttatata cttcaagcgt ttgtggaaat acaattattt tccagatgtt gcaataaatt
     7201 atagagagta aattatattt aagtagtaat cgtatcaaat catagattat cttaatttat
     7261 aattcatatt aaaattacca gtctaactca aattcaaaat catccgactt tatctgttca
     7321 atttcagaat ttaccttctg tttaaattta ttagaagaaa tcatatatac aagaaatatt
     7381 aaaccaaata ttatttgtac atattgagct attacacata atttaatagg gtagtgtaga
     7441 agtaattgaa tgttgaaaaa atagtacatc atatgaacta acccagctga taaaatgctt
     7501 ctacttgtat tgatatatac aaaattaatt ataaagttta aaagtacaat gtttggtata
     7561 aataaaaaag catcaaatag ggagtattgt gccaaattat atggtatttg attaggtgta
     7621 aaatacgacc ctagatacca gattccacaa acaagcccta aaataattga agagcctata
     7681 aatccaaatc taactaataa tttgtcaatg gcatatcctc tccatccagc ttcttgacta
     7741 agtatactca atataaaact tgctaatagc atataagcta ttttagaagg tctaaacact
     7801 gctatgtgta tccaatctat atcagaagtt tttacattaa agtaatttcc gattattaac
     7861 gaagtaataa aagttaaagc aaaaaataat attgttaata gtatccattt tattctaatt
     7921 tctttaaagc ttaggtatct ataaataaaa tcttgttttg cactttgtgg atagattgta
     7981 gaaataaaaa atagacctac aatagctggt gatgtatatg caagataaaa aatgatttct
     8041 ccaagtattg tatttgtaat tccgagcaac gcaggtgtaa gactgaatat ccagttcaat
     8101 actagcgtaa atgtaaagaa atagattaag tgtttgtttg tattaaaggg ggtgttatat
     8161 agttgcattt tttcactatc cttccgtttt ataatgaagt tttaattttt attaattgtt
     8221 tatttatttt tatatgtatt aagttatcgc ttgatgttag ttattgccta taataatatc
     8281 ctatttttta tattttgatt aattattttt acactaaata taattaatta gtatttaata
     8341 ttgaatatat tatattatta ttaattatta aataggtcaa taaatttgca attagtgata
     8401 ttaataaatt actttagatt tttattaaat gtttagcttt tctttaatat tttttatata
     8461 acgacgattt ataataactt tttcgttgtt ttttaaagta gcttgcatgc gattatgtga
     8521 tattactttt atacttttta tgtagtccat atttaaaatc atggatttag atattcgtga
     8581 gaaggatgta ttagctaata attttgataa tttatatatt tttaaatcaa tttcaaatac
     8641 atcatcttca taataagcaa atgttttatt tccaactgtc tcaaagtata aaatatcaca
     8701 gacattgagt ttataaatct ctcctgattt tttacctttt atatcaagta acggtgtact
     8761 caataatgaa attatttttt caatgttatt atctagagca gaacatttta tggttatttc
     8821 aatatcatca caattaatac cttgttcgac atgtattttc attaatcatc acctcatttt
     8881 attactgtca ttagaatagc attatatctt attgagtcca actagatgcg ttctaaattt
     8941 caaattaagc atagtgaaat tcaaaaataa aacagtgaaa ttcaaatttg aggtggtaaa
     9001 attcaaaaaa atactatgga tatttggata aattatccaa atatcctagt atttcacata
     9061 gaatatgtct aattatttta caaatagacc tattttatga cttacatata ttgtcaaatt
     9121 acttcttaaa tatcaaaata tttttggata atgtatcaat actgtttgat aaagtattta
     9181 atttaccctc aattctaacc aataagtaca tggatagagc tataggaaaa ccaacattgg
     9241 ttattaacag ttgtaaacta tcatccataa aattagcccc ctattctata actaagtcat
     9301 aaggagtggt atttgtttcc acaaccttgg cttcaacaac agaagctagg tcaaatcctc
     9361 caaccgaaaa aatattttta gatactatca aatccatgac agattttata ttttcttcag
     9421 ttaaatcatc ctttggattt tctatagaaa aagaaacttg tttatccttt acatttttaa
     9481 agctcatgac taattttttc ttaatttcca tataattacc tccgatataa taatttatat
     9541 tttaattgtt tgcttgttaa tattggtatt ttaattgtca atattaatgt tttgcttgtt
     9601 agtattaata tttcaattgt caatattaat gttttgcttg ttagtattaa tatttcaatt
     9661 gtcaatatta gtgtcttgct tgttagtatt aatatttcaa ttgtcaatat taatgttttg
     9721 cttgttagta tcagtgtttc aattgtcaat attagtgttt tgcttgttag tattaatatt
     9781 tcaattgtca atattagtgt cttgcttgtt agtattagta tttcaattgt caatattagt
     9841 gttttgcttg ttagtattag tatttcaatt gtcaatatta gtgttttgct tgttagtatt
     9901 agtatttcaa ttgtcaatat taatgttttg cttgttagta ttagtatttc aattgtcaat
     9961 attagtgttt tgcttgttag tattaatatt tcaattgtca atattagtgt tttgcttgtt
    10021 agtatcagtg tttcaattgt caatattagt attttaattg ttgactctag ttattgctga
    10081 tatagaaaat atttaattta tttcaattaa ttagattaaa gtagggtagc atctaaaata
    10141 gctaacatgt ttaagttgaa atacgtttaa tatattaatt tttcaaagca ttaatatatt
    10201 aaagttataa tcaaaattga agttataatc tgccaaatct atagcgtatt aagtgcgtta
    10261 tataacttaa tcttttatat aaagagttaa tttttttaat ttgtaaagca gagtacgttt
    10321 aaaaggtact atttagataa tgatgtacta tctaatttta aaatatctac aatagggttc
    10381 tcttgaagac ttgctattgc ttctgcaaca gcataaacat cttcatttaa tgcctctgct
    10441 tttacatttg caaatgattt acttttaaca actgccttac ccttatcatc aaaaccagca
    10501 tccaatttta gttttatact agataaattt tttgttgaaa caacttccat aaaattacct
    10561 cctaaaaatt taatttcaaa gatttgtcga ctttctttgt tagctataat actatcatct
    10621 aagataatat cggagttaaa cagtaatttc taaagatttt ttgtgtaaat ttttatagga
    10681 aaaattttac ttttttgctg atgaaaaagt ttacaagtta tttgtgaaga tatgttctta
    10741 gtgttttgaa atagtatttg tatatattca tgcttagttg agatagtttt gtatggattt
    10801 tcatatgtgt agagttaaat gttaggtact aaagtttatg ttaaattaaa tgttaaagct
    10861 tatgttaaaa attttattaa atttaatctg taaataaaaa agttaaaagt ccaatattaa
    10921 cattttactt ttaaaccatt aaaatcttta ttaaagctaa caaagttata agttatgaga
    10981 aattttatta aagttaatac aaaaattaat tttaaagcta agaaattttt tattagattc
    11041 aataaaacta ataaatatag tttagtcaat aatgtattaa ataaaaactt tgttaagtct
    11101 ataaaaatat cttaaaggag gtgtaactta tgaagataaa agtggaggat ataccagttc
    11161 aatttcatgc aatggtagaa ataattggaa ttgataagtt tatagaggtt gccaagttgt
    11221 atggaggaac aaatacttat atacctacgt ataaggggct ttttagatat gctagaaata
    11281 gggatatagt aaaacaattt aatggagtca accacaatga attggctatt agatataata
    11341 tgtgtgtaag caatattaag cgaatactca atgaaaataa tgtttaaata taataaaata
    11401 atgtttaaac ataatgaaaa tagccttgtt aaacgtaaga gtaaagacaa agaagatgtt
    11461 ttataaagtt tttttagaca aattaactaa atttactact tattaattta aatacattgt
    11521 atattctata aaaaaatttg ttaaatactg gagatatatt gagaatacaa agaaaatggt
    11581 cgaaaatatt tgttggctaa aaaatagata aaatgataca attgcttgta taaaggggaa
    11641 aaataaataa ataaactata taaataaaga aatagcaatt aatatgacat aatatattta
    11701 taaaattaag aatataaata gatattttaa ggtattagtt gttaaattag gaaatattaa
    11761 aaaaaatata tatttatatt taaactattt tgttatttat ataaaaatac ttatctagtt
    11821 actagcaatt attagtagaa atgggggaaa tagagatgaa taagggattt tacaaattaa
    11881 attcagtggt attgaacttt gatattaaga atgatgttaa caagataaga tttaatcatt
    11941 atataatgag aaaagaaaac atacaaagac ttcaaggaac tctgccaaac ggacaatttt
    12001 atatgacagt gagaagagct gctacagatt tacaactttc tatttctact ataagtaggc
    12061 ttgtaaaaga gtttttggat ttagggataa taagattagt gtctaagggt gtaaaaggta
    12121 atcgttctgt atatagttac gtaagtatag agtttaatgg aagtttattt gatgatagca
    12181 aatatatgga acttgactgt gtatgtaatg atgaatttat tgataatagt ggcatagagt
    12241 ttgattgtga tagcaaagat aattctttta atggagatat aaatgtagaa actgtgcatt
    12301 gcattaatga gtatttgtct gatgatgatg tagagcataa ttataacaat ttccataata
    12361 aagatactat aaaggataaa gccatttcta atattagcac tatcaaaaaa tatattgatg
    12421 aatcttttga taaaaataaa tcagaaaatt ctaacttaca acaggagtca ataaatttca
    12481 actttaatga tacatgcaat gaaatagata aaagaacgaa taatagtata gaaaataatc
    12541 aaaataaaag gcctatgaga ttgagtgaca tcagtctttt aagtgataaa ggtatgacaa
    12601 ataaaaagaa ttactttaat cataatcatg gtatacaaaa agggactaaa tctgtaacaa
    12661 agaaaaaaga atccttaaat aaatttaata aaaaaaatat acagcaaagc attataaata
    12721 tgctaaataa aaaatcaggt aagaatttta aaatcgattc tccaataagc ataaaactta
    12781 tcaatgaaag gctaaaggaa ggctatgtct tagaagattt ctacaaagtt attgaggtaa
    12841 aagtggctaa gtggaaaaat accataatgg aaatgtatat aagaccagaa actttgttta
    12901 gctataagtt tgaatcctat gtaaatgaaa acatatctat gaaaagtcaa agtaatgttc
    12961 acccatgtaa agaaggcaat agtaatgata gcagtaatta tatacattct gattatacaa
    13021 catatgatgg cagtgtgcgt gagagaaaaa aatatgagaa tgtaagatac tggaatccta
    13081 tatgtgaaat ttaattagtt taagaatgta tttatgataa ataagatatt aatagagaat
    13141 agtgagctat agcaaatgat atatcaatag ttggtagtaa gttatattaa gcaagatatt
    13201 actatcaggt agtgaattat attgaacgat atatcaataa ttggtagtaa attatattaa
    13261 gtaagatatt actatcaggt agtgaattat attgaacgat atattaataa ttggcagtaa
    13321 attatattaa ataagatatt aatatcgagt aatgaattat attgaacgat atatcaataa
    13381 ttgg
//
LOCUS       DAJMZY010000112        13327 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.113, whole genome shotgun sequence.
ACCESSION   DAJMZY010000112 DAJMZY010000000
VERSION     DAJMZY010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13327)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13327)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13327
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.113"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            185..1522
                     /locus_tag="OE968_003127"
     CDS             185..1522
                     /locus_tag="OE968_003127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HCP7220386.1"
                     /translation="MGTYSLISTSINFILILINIFIAFFLYTLTSYFIDFRNHWIFKI
                     ILILGYSIISQMIIWLSDPVNILFTLFGYFILLIICSKSKLIPIISVVMIFYPIIIGL
                     NFLFINNPIYEELIHSKEYILILSIVQIISALIKLLFWFLIHIFLKNRLVNIKQYLSN
                     KIWIFIDMVCISSFLSILIAIILPPTNLIPMGSNKNIILGNLPYGTYLIILSAILANI
                     GVILLLQPLIENVKMKIEKQANHLKEKYYNLLENQQIQIRKMRHDMNNHFQMIESYLE
                     IEDIAGAKKYFNQLKIGIGTLSGKQFCKNQALNSILNLRHTSLEENGVDVHFNIDIDN
                     HLGIEPIDLCTIFSNSLDNAIEASLKIPDLSNRKVVLKARCEKEYFSYLLTNNKVNPI
                     NRKQELFISDKKDSNSHGYGIENIREIVNKYNGKLDISYTENEFSLFLYIRLF"
     gene            complement(1858..2427)
                     /locus_tag="OE968_003128"
     CDS             complement(1858..2427)
                     /locus_tag="OE968_003128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GrpB family protein"
                     /protein_id="HCP7220387.1"
                     /translation="MKKKLEDMTLEELWNLFPIFLTTHKECWKNWFKEEQYRLTGILP
                     MQKIVRISHIGSTSVSTIYAKPIVDILIEIIPDYNMKDIKDLIESNGYICMSESSSRL
                     SLNKGYTVDGFEERVFHLHIRYVGDNDELFFRDYLIDHPDVAKEYEKLKLDLWKKYEH
                     NRDAYTDSKLDFVREFTEKAKVLYFNRYN"
     gene            complement(2783..3796)
                     /locus_tag="OE968_003129"
     CDS             complement(2783..3796)
                     /locus_tag="OE968_003129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M56 family metallopeptidase"
                     /protein_id="HCP7220388.1"
                     /translation="MVSSFLNDIFRTILVSCIFIVILLVFRITLFKIFSKKFNYYIWL
                     IVIIKLSLPFMNYTFIFNESKYNGNINKISLGNFNSISIVYSTVLVSVWIAITIFYLV
                     YTLLKYIKLKNMINDLSYDVEDDKIKNLYENLLKELKINKKIRLKYSYEVESPVFFNS
                     CVILPPSDYTLKELNWIFRHELMHFKSKDLYIKYLVIFLKCVYWFNPFVYIMEKFIDL
                     DCEFYCDERVLKNCTIEEKQDYALTIISAMRKGSNSSNKFVAGLHKESDIKKRVFSMF
                     NEKYRNGILIAVILCLLSSITYFKIDLITTKSIFYPLSKQTPIENRTNSKPTYQINVY
                     IDN"
     gene            complement(4408..5310)
                     /locus_tag="OE968_003130"
     CDS             complement(4408..5310)
                     /locus_tag="OE968_003130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HCP7220389.1"
                     /translation="MLPQDYYGLIVILGVILGVMGAFYNWFTLYVQSLYKKIPKIGTF
                     GKLLIPFIMAGILGLVMPDVLGSGHNLVEELTSHEYIFGMVVLIFVIRFIFSAVSFGS
                     GAPGGIFFPLLVLGAFIGGIFGMVGVKVFGMNPDYVNNFVLLAMAGYFTAIVRAPLTG
                     IILIFEMTGSVSQMLSLSVISIVAYIVATLMKSKPIYESLLERLLEKNGEPVHKERGE
                     KILDQFSVMFGSPVANKAIQDVQWPENCLLVAIQRGGEEIIPRGKTILRPSDVIVTMT
                     DERDSGAVYDKMENLCKEHTSHIF"
     gene            complement(5437..5556)
                     /locus_tag="OE968_003131"
                     /pseudo
     CDS             complement(5437..5556)
                     /locus_tag="OE968_003131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888399.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(6102..6764)
                     /locus_tag="OE968_003132"
                     /pseudo
     CDS             complement(6102..6764)
                     /locus_tag="OE968_003132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016440163.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
     gene            complement(6924..7460)
                     /locus_tag="OE968_003133"
     CDS             complement(6924..7460)
                     /locus_tag="OE968_003133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GrpB family protein"
                     /protein_id="HCP7220390.1"
                     /translation="MIGLKCGMVKLLEHQMIWDKSAKDVIILLKSIWDKTAIDIQHIG
                     STSIPSISAKPIIDIVVGVASLEEAKLYLERLEQCGIVFRGQDVPKQLLFAMGDFEKN
                     TRTHHIHVVEWNGVAWNNYINFRDYLNTFTDKAKLYDSHKQKLALQFEDNRKIYTQRK
                     QELINILLEEARLWRINT"
     gene            complement(7533..7946)
                     /locus_tag="OE968_003134"
     CDS             complement(7533..7946)
                     /locus_tag="OE968_003134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003507530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3795 domain-containing protein"
                     /protein_id="HCP7220391.1"
                     /translation="MKMPKESIDTIMFAPCGMNCMVCYKHCYHKKPCAGCLNGDTGKP
                     EHCRKCKIKDCVCQKGLFYCFECFNFPCKLIKNLEKSYNKRYQASLMENSKFVQQYGL
                     EKFMQKQKERYTCSKCGGIISIHDRECSECQEKVK"
     gene            8412..9029
                     /locus_tag="OE968_003135"
     CDS             8412..9029
                     /locus_tag="OE968_003135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid stabilization protein"
                     /protein_id="HCP7220392.1"
                     /translation="MDEKILELLQEMQGSISGIEGTISDMQSNINGIEGTISDMQSNI
                     NGIEGTISSMQGNINGIENTISGMQGTIGDMQGSISGMNGTISDMQGSISSMDGTINS
                     MQDSITDMQVEIKEVNSKLDNMEPDIKDLKTGQVETSSRLDTIQSDVTEIKSDVKINR
                     NTLDTVIKHTSSLVKDTSDIKNDLNNIEIVTSKNSNDIAKLKSVK"
     gene            complement(9637..9816)
                     /locus_tag="OE968_003136"
     CDS             complement(9637..9816)
                     /locus_tag="OE968_003136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HCP7220393.1"
                     /translation="MLQTGKQGADKKYLDNMFFVKGYVEELLFLDNNYNIVFSCIVFH
                     HCTNVQNIFCIFWKW"
     gene            complement(10042..10575)
                     /locus_tag="OE968_003137"
     CDS             complement(10042..10575)
                     /locus_tag="OE968_003137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HCP7220394.1"
                     /translation="MQYISYYHSPIGNILLASDNIGLTGLWFENQKYYAYNLDQEHQE
                     KELPIFEQTKKWLDIYFSGKEPDFTPSLHMVGTPFQTTVWKILQQIPYGKTITYGEIA
                     YKVAQQKGISKMSAQAIGGAVGHNGISIIIPCHRVVGTNGSLTGYAGGINRKIKLLSL
                     EKVSVQHYFIPKKGSAL"
     gene            complement(11996..12568)
                     /locus_tag="OE968_003138"
     CDS             complement(11996..12568)
                     /locus_tag="OE968_003138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HCP7220395.1"
                     /translation="MWIYQKTLEHPVNIRQADPRMAKYIMTQLGGPNGELAAATRYLQ
                     QRYTMPTGKSRALLTDIGTEEMAHVEIISSVLYQLIGNCTPEELKAAGLGSNYANFGH
                     GLQPVDSNGVNFTTSYINVFGDSVTDLHEDMAAEQKALATYYQLINLTDDPDLKDILR
                     FLGEREVVHYQRFGEALMDVYEFTECKHQF"
     gene            complement(12630..12893)
                     /locus_tag="OE968_003139"
     CDS             complement(12630..12893)
                     /locus_tag="OE968_003139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat protein CotJB"
                     /protein_id="HCP7220396.1"
                     /translation="MSLNRRELLERISEYQFACIELNLYLDNNPRDKKALDSYNRYCD
                     KFTQAVCDYESKYGALTNFGYESSEYPWSWISEPWPWDKSFYK"
     gene            complement(12893..13114)
                     /locus_tag="OE968_003140"
     CDS             complement(12893..13114)
                     /locus_tag="OE968_003140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat associated protein CotJA"
                     /protein_id="HCP7220397.1"
                     /translation="MGYLKEDKQDYCCEFARPYINRQIYDDTYNPKTALKRGTLFPEL
                     DLIESNNYNDWLYANPKNRVRAKKGGNMY"
BASE COUNT         4721 a         2247 c         1500 g         4859 t
ORIGIN      
        1 aattttttga aacttaattt ttaaaatttc aatcttttaa aactcaattt tttgaagttc
       61 aatctctaga attttatttt tcaaaatcaa ttctttgaaa tttaatttcc agaattttaa
      121 tttttaagat ttaatttttt aaaacttagt ttccagaatc ttaattaata gaaaggtata
      181 ttaaatgggc acttattctt taatctctac aagcataaat tttattctaa tattaatcaa
      241 tattttcata gccttttttc tttatacgtt gacttcctat tttatagact ttaggaatca
      301 ttggattttc aaaatcatat tgattttggg ctactctatt attagtcaaa tgataatatg
      361 gctttccgac cccgtaaata ttttgtttac actattcgga tattttatac tacttataat
      421 atgtagcaaa agcaaattaa ttcctataat atcagttgtc atgatatttt atcctattat
      481 aattgggctt aattttcttt ttataaacaa ccctatatat gaggaactta tacactcaaa
      541 agagtatatt ttaatacttt caatagtcca gataatttct gctctaatta aattattatt
      601 ttggttttta atacatattt tcctaaagaa tagattggtc aatataaaac aatacttatc
      661 aaataaaata tggattttta ttgatatggt atgtatatct tcatttttat caatattaat
      721 tgctattatt ctgccaccta ctaatttaat ccctatgggt agtaataaga atattatctt
      781 aggcaactta ccttatggca cttatctaat catcttgtca gcaattctgg caaatatcgg
      841 tgtgatactt cttttacagc cattgattga aaatgtaaag atgaagatag aaaaacaagc
      901 aaatcatcta aaagaaaaat actataactt actagaaaat caacaaattc aaatacgcaa
      961 aatgcgacat gatatgaata atcactttca aatgattgaa tcgtatttag aaattgaaga
     1021 tattgctgga gctaaaaagt attttaatca gttaaaaata ggtataggta ctcttagtgg
     1081 caaacagttt tgcaaaaacc aagctcttaa ctcaatttta aatcttcgtc atacaagttt
     1141 ggaagaaaat ggtgttgatg tgcactttaa tatagatata gacaatcact tgggtataga
     1201 acctatagat ttatgtacta ttttttcaaa ttctttagat aacgctatag aagcatcttt
     1261 gaagattcct gatttgtcaa atagaaaagt ggtattaaag gcacgttgtg agaaggagta
     1321 ttttagctat ttattgacaa acaacaaggt aaatcctatc aatagaaaac aagaactatt
     1381 tatttcagat aaaaaagata gtaattctca cggatatggt attgagaata ttagagaaat
     1441 tgttaataag tacaatggaa aattggatat ctcttatact gagaatgaat tttctttatt
     1501 tctttatatt agattatttt agtctaaaat tagattatct tatataatac aaattagatt
     1561 gtttgatact atgtaaaatt ataataactt ataattaaat atttacacat atattcatta
     1621 acttaaaatt taatcaaatg tgatatttta tttaccttag taaaaatgtg tgtgtctcaa
     1681 aataaacttt ttagttgatg aggcactctt ttttacatga aatcaaatat atttttatcc
     1741 tttcaacaat gaaaaaggga tttatctctc cattttgaaa caaccccttt ttctattaat
     1801 tactttctta aaaaatataa tacgatatat aagataaata tctaattgta cctatttcta
     1861 attatatcta ttaaaataca acacctttgc cttttcagta aactccctaa caaaatctag
     1921 tttactatct gtataagcat cacgattatg ctcatacttc ttccaaaggt ccaacttaag
     1981 tttttcatac tcctttgcaa catctgggtg gtcaattaag taatctctaa aaaacaactc
     2041 atcattatca cctacatacc ttatatgcaa atgaaaaact cgttcttcaa acccatctac
     2101 tgtataccct ttattaagtg aaagcctact actgctctca gacatacaaa tatatccatt
     2161 cgactcaatc aaatctttaa tatctttcat attataatca ggaattatct caatcagtat
     2221 gtcaacaatg ggcttggcat aaatcgtact cacagaagta cttccaatat gacttattct
     2281 aacaattttt tgcattggca atattccagt tagtctatat tgttcttctt taaaccaatt
     2341 tttccaacat tctttgtgag tagtcaaaaa tataggaaac aagttccata actcctctaa
     2401 agtcatatct tccaacttct ttttcattag ttacctcctt ttaaatttgt actttatatt
     2461 ttttcttttt caaatttact tagttaatat ttaactttat tttttatcaa atcatttttc
     2521 taattatgta aatttttcta aatttagttt ttaatgtatt ataacagatt tttacccttc
     2581 ttacacttgt gtatttcttt aaatattaga acacttttta atctgcaatt gtagtaaaat
     2641 atttttcttt acctgtattt actggcattg gagcttctaa agaataattc attggcttta
     2701 atataattaa agtaaattta acatatgtga aagatactta ttaaaattat ttatattaat
     2761 ctcttgttaa actttgtatt ttttaattat ctatataaac attaatctga tatgtaggtt
     2821 ttgaattagt tctgttttca ataggtgttt gttttgaaag tggataaaat attgatttag
     2881 tagtaattaa atcaatttta aaatatgtaa tagaagataa taaacataaa ataactgcta
     2941 tcaaaatacc atttctgtac ttttcattaa acatactaaa cactcttttt ttaatatctg
     3001 actccttatg taatccagcc acaaatttat ttgaactatt tgaacctttt ctcattgcac
     3061 taattattgt caatgcataa tcctgcttct cttctatcgt acaattcttc aaaactcttt
     3121 catcacaata aaattcacaa tccaaatcta taaacttctc cattatatac acaaaaggat
     3181 taaaccaata aacacatttt aaaaatatca ccaaatactt aatataaagg tctttactct
     3241 taaaatgcat caactcatgc ctaaatatcc agtttaactc ttttaatgta taatcacttg
     3301 gtggtaaaat gacacacgaa ttaaaaaata ctggactttc aacttcatat gaatatttaa
     3361 gccgtatttt tttatttatc ttaagctctt ttaataaatt ttcataaaga ttttttatct
     3421 tatcatcctc aacatcataa gacaaatcat ttatcatatt tttaagctta atatatttca
     3481 ataaagtata aactaaataa aatatcgtaa tagcaatcca aacagagact aaaacagtac
     3541 tatatacaat agaaatacta ttaaaattgc ctaaacttat cttattaata ttaccattat
     3601 attttgactc attaaatata aaagtataat tcataaatgg taatgatagc ttaataatca
     3661 caataagcca tatatagtaa ttaaattttt tactgaaaat cttaaataaa gttattctaa
     3721 agactaataa aataactata aaaatacaac ttactaaaat tgttctaaag atatcattta
     3781 aaaatgaact aaccacagat actcaccttt cttatacttt tatatttata taatcatcta
     3841 cacgaatact aaactgatat gtaggttttt aattaacttt gttttcaata ggcgattgtc
     3901 ttgaaagtgt tttaaaagtt gatataacaa tgatttagga gtaataaggt caattttaaa
     3961 atatgtaata aaatataata agcatgaaac aactgctatc aagataccat ttccaaactc
     4021 tataagcaaa aggggctaat acaaccttaa ccccttttaa ttattttcat ttataaataa
     4081 attctattct tcccaaaata tcgcaattaa aatatattaa ttaaaatatc ccagtaagaa
     4141 tatctgaaaa atcttctacc tattttttca aaccctttat tcccattcct catacaatag
     4201 tgcaactttt agcacagtat aaatatacca ttagtccata taatctcatt aacaaatata
     4261 tacaattatt ttcttcaaac tcttttacat ctaagatatc acattttcat tttcttatat
     4321 taattcctta actctctttc aaattaccaa ttttttaatc aaatcttcat taaatattct
     4381 atcattatta aacattcatc attatcccta aaaaatatgt gacgtatgtt ctttacacaa
     4441 attttccatc ttatcataca cagcaccact atctctctca tctgtcatag tcacaattac
     4501 atcacttggt ctaagaattg tcttacctct aggaataatt tcttctccac ctctttgaat
     4561 tgctaccaaa agacaatttt caggccactg tacatcctga attgccttgt tcgcaacagg
     4621 agagccaaac ataacagaga actggtctaa tatcttttcg cccctctctt tatgtacagg
     4681 ttctccattt ttttcaagta acctctcaag aagactttca taaataggtt tagacttcat
     4741 aagtgtagcc acaatatatg ccacaattga aattactgat agtgaaagca tttgactaac
     4801 agaacctgtc atttcaaaaa ttaatatgat accagtcaaa ggggcacgca caatagctgt
     4861 aaaatatcct gccatagcca aaagcacaaa gttatttaca taatcgggat tcattccaaa
     4921 aactttaaca cctaccatac caaatattcc acctataaat gctcctaaaa caagcaatgg
     4981 aaaaaatatt ccccctggtg cacctgaccc aaaactaaca gccgaaaata taaaacgtat
     5041 aacaaaaatc aaaacaacca ttccaaaaat atattcatga cttgtaagtt cttcaactaa
     5101 attgtgtcca ctccccagaa catcaggcat aacaagccca agaataccag ccattataaa
     5161 tggaatcaac agttttccaa acgtaccaat tttaggaatc ttcttgtata aagactgcac
     5221 atatagagta aaccagttgt aaaatgcccc cataactcca agaataacac ctaaaatcac
     5281 tattaatcca taataatctt gtggcaacac atttccaatc tgaacctccc atgactaaag
     5341 tcacagggtt cctgcttcat agaattttgc atactaacat atgtcttact aattctccac
     5401 aggctatccc cgtagttcct acggttctta cataagttat ttattttgaa ttgttattag
     5461 tcttaatcct tcttttaata tatttatact tgcatttata tctctatcgt gagtttcatt
     5521 acaactagga caaatccatt ctcttataat aatgttaaca aatgtaatta tttaaaacaa
     5581 ttatttagaa ggttttatat ttaattttaa ataacatatt taagaaccgt aagtcttaac
     5641 ttttatcatt tttgaggttg tcgttcacat aagttcgcta ctacctatgc agttctctta
     5701 tgaacttctt acactttcat gcaagcacag actatatctt atccttcggc attatccgtt
     5761 aaggtctacc cacttccact accaatagct tgtagtgtac ttccctcaag aggaatagtc
     5821 gttgaagttt ctcctattcg gagtttacct gctgattgcc cattttaaag tacttaggat
     5881 ttaaccttat accatctaac caattttttc tactttcgta actttcacac ttaggtttat
     5941 ttcatcctta tgttttagtt tggttagctt taggggtttc cagcaattca agtagtattg
     6001 gataggttct atcctatctc tacatatagg tttccctata tgctgactat tttagctact
     6061 aactcatgac taaagtcaca agtgtgcgta gctatttttt aatcaaactg gaatacagac
     6121 tccattccta ggaaattggc tgaaatatag tctgctgtca aagatgctgt catcacagaa
     6181 attaaaacag atactgaaaa gtttttatgg acttcttcaa gtgaaaacat aacacccgcc
     6241 agtggtgcat gaaaggctgc tgataatcca gcacttgccc cacaggttaa caggaatttt
     6301 tcctctgtct tccctcggtc aagagctcta gaaatacctt tacctgccat agcaccaagc
     6361 tgaatggaag gaccttccct tcccaaagca agaccaccca tgagtgataa gaatcctcca
     6421 ataaattttg ttggcaacac tcgccaccat acttgtttta ttttccctgt catttccccc
     6481 tcaagctgag ggataccact tccagaaatc attggctccc agtccaccaa ctttgataca
     6541 atccatgcaa gtactgcaag tactgcaaac caagctatta tttttattgt agaaccttct
     6601 acaaatttta aaatttggct aagccaagta ccagcctgcc ctaaaagtat cctgtataaa
     6661 agcacaatca aaccagccac agccccaacc ataagtcctt caccaatcaa aattacctga
     6721 aagtgctctg cccgtttgat aatatgagat gtatcctttt tcatactgtt cctccttcat
     6781 ccaataattc tacacaatct gaatctccaa tgactaaagt catgagtgtg tacagatatt
     6841 ttttaatcaa caaaaataga tttttattta ctaaatataa gaaaataatt gctcaatttc
     6901 tcaataaatg taaatttatt cttttaggta tttattctcc acagtcgtgc ttcttccagc
     6961 aaaatattta ttagttcttg ctttctctgt gtatagattt tacgattgtc ctcaaactgt
     7021 aatgccaatt tttgtttatg actatcatag agttttgctt tgtctgtaaa agtatttaga
     7081 taatctcgaa aattgatata attattccat gcaacaccat tccattcaac aacatgaata
     7141 tggtgagtac gagtattttt ctcaaaatct cccatagcaa aaagtaattg ttttggtaca
     7201 tcctgacctc gaaaaacgat tccacattgc tctaaccttt cgaggtataa tttagcttcc
     7261 tctaaagaag caacacctac aacaatatca ataataggct ttgcgctaat actgggaata
     7321 gaagtgcttc caatgtgttg aatatcaatg gcagtcttat cccatatact tttcaataat
     7381 ataatgacat cttttgcact tttatcccat atcatctgat gttccaataa tttaaccata
     7441 ccacatttta aacctatcac tatataccac ctcaatataa tccaccttta tatatattac
     7501 aattttttct ctcttgataa acagtgattt agctatttca ctttttcttg acactcgcta
     7561 cattccctat catgaataga tataattcct ccacatttag aacaagtata tctctccttc
     7621 tgcttttgca taaacttctc taaaccgtac tgctgaacaa atttactatt ttccataagg
     7681 cttgcttgat atctcttgtt ataacttttt tcaagatttt ttatgagttt acaaggaaaa
     7741 ttgaaacatt caaaacaata aaacaaccct ttttgacaga cacaatcctt tattttacac
     7801 ttacggcagt gttctggctt tcctgtatcg ccattcaaac aaccagcaca tggctttttg
     7861 tgataacaat gcttatagca aaccatacaa ttcattccac aaggagcaaa cataatcgta
     7921 tcaatactct cttttggcat tttcataaca ttttactcct ttcaaaaatc caatttgtcg
     7981 aattgttata tattcatatt gtaacataaa aaatagctaa aaaattcatg cactttcatt
     8041 gccaataaat tttcaaggaa atatgaaagt ttaaaactaa gaataaaaag agataaaaag
     8101 gaagctacta atcaaattat tcaaatacaa gtaatcaata taaataactt aaggtatatt
     8161 taaaagtata tgatattacc agcagtttta aatacaaata taaccacaca tgcctcaaaa
     8221 acacttatta cagtatctta gaaacttaga caatacataa gattcattaa taaaaaagtt
     8281 ctcaatatag atatatttaa ccatgttttg aatagcagat aatcatatga ttaaaaatta
     8341 aatatgacat agcgtttgtg gaatataaca cctaaattat gttataataa taaaacagga
     8401 gtgtgatagt gatggatgaa aaaatattag agttattaca ggaaatgcaa ggtagtatca
     8461 gtggtatcga aggcactatt agcgatatgc aaagcaatat caatggtatc gaaggcacta
     8521 ttagcgatat gcaaagcaat atcaatggta tcgaaggcac tattagtagt atgcaaggca
     8581 atatcaatgg tatcgaaaac actattagtg gtatgcaagg cactattggc gatatgcaag
     8641 gtagtatcag tggtatgaat ggcactatta gcgatatgca aggcagtatc agtagtatgg
     8701 atggcactat taatagtatg caagacagta ttactgatat gcaagttgaa attaaagaag
     8761 tcaatagtaa gttagacaat atggaacctg atattaaaga cttaaaaact ggacaagttg
     8821 aaactagtag tagacttgat actattcaga gtgatgttac agaaattaag tcagatgtaa
     8881 aaattaacag aaatacatta gatacagtga ttaaacatac ctcttcatta gtaaaagata
     8941 catcagatat taaaaatgat ttaaataata tagagatagt cacatctaag aattcgaatg
     9001 atattgctaa attaaaatca gttaaataat ataccatagt aaaaaatacc tgaaaatttc
     9061 acatacttct ttaaagttat accaaatttt atacagaaat actgattatc cgacaacaca
     9121 ctttacttat aaataattta ttaaaaaaat actcatttta tcctaaaatt aacacgacta
     9181 aatgagtctt gatataataa taaaaaataa gggagattgg acactaaaaa gttgtgtatc
     9241 tcccttatat cctataatat agttatataa tttttcagcc taaaataaaa gtccatcttt
     9301 gattaaaaca catcccctta tcacttataa aaggataaaa tcttgttttc atttttccat
     9361 ttatatcttc ttgcttaaga gtaataattt tttcttttga tactttaagt gtttggttaa
     9421 atttaactaa tcgactaagt tttgttcaac atctattttt catattttcc aatacttaat
     9481 ctatttttta taaataattc tttcatttct aactcactta cattttttac ataaaacgaa
     9541 acatataaat ttcaacctta tcttgtatgg ttcttaatac ttaatgagta gcttaagtat
     9601 caatcattat aaatttttcc cttacattta acactcttac catttccaaa atatacaaaa
     9661 tatattttga acatttgtac aatgatgaaa tacaatacat gaaaatacaa tattataatt
     9721 gttgtctaaa aatagaagtt cttcaacata acctttcaca aaaaacatat tatctaagta
     9781 ttttttgtct gctccttgtt ttcctgtttg tagcatataa attacttcct ctaaacatat
     9841 aactactcac atgaaaaaag aaaataaact tccaaaatac aagctctaaa aactacctct
     9901 aaagttgtat aatgtttact aggaataagg ttgtataaca tatagtttaa ataatcattt
     9961 tttaaaattg caagttattg ctttcaaaat tagatgtttg tatatcaaat aaatgattaa
    10021 gaatttctaa atttaatggc tttataatgc actccctttc tttgggataa aataatgttg
    10081 cacagatact ttttctaaag ataacaattt tatttttcta ttaattccac cagcataccc
    10141 agtcaaactc ccatttgttc ctacaacacg atgacatgga ataataatag agattccatt
    10201 atgccctact gcaccaccaa ttgcttgtgc tgacatttta gatattcctt tttgttgagc
    10261 aactttatat gcaatttctc cataagtgat tgttttacca tatggtattt gttgtaaaat
    10321 tttccacact gtagtctgaa aaggagtacc taccatatgg agtgatggtg taaaatcggg
    10381 ttcttttcct gaaaaataaa tatctaacca tttctttgtc tgctcgaaaa ttggcaattc
    10441 tttttcttga tgttcttggt caagattata agcataatac ttttgattct caaaccaaag
    10501 accagttaac ccaatattat ctgatgctaa aagaatattt ccaattggac tatggtaata
    10561 gctaatatat tgcatacaat tcctccttat attctgaaaa cttcactcaa atcattagac
    10621 acttcttttc tatctaccat tatgtaaaaa catactaata taatttcctt ctaactacac
    10681 tttcgttata atatctatcc tcatatcata ttagttttat atttacctgc atctgttcat
    10741 ccttttttcc ctttcccttt gatggatata aaattcatac atttaagctt cctactgtat
    10801 taacttttat agaagtgtat cttataattt tatcactaaa tagaccaaaa aaatatcgat
    10861 atagcatcaa gtaatatcat aatactttca aatgggaaaa gtaagaatag gctgtaaaaa
    10921 agaaaagtat ttttatgtta gaaatccagt aaaatcgtta gtagatagaa taacagaaaa
    10981 cgaacaattt gctatttatc attttacaca taaatataat tgacgcaata aagtgttttc
    11041 tattctacaa cgattaataa ggttagaaaa aagtaaaaat gaactgtata tgtatgaagc
    11101 attagtttct gtttctttcc tttggcttat tatgataaaa aatattgttt tgccaccaat
    11161 aaaacacaaa aatataatta atatccatat gcaaaaaatt ttacgttata ttgaaaaata
    11221 ctattgtttt acattatatt gaagggtact attgtgaaaa cttaattttg gagtactatc
    11281 aagcagtggt aatatcaata aatcagagtg ctccagatga tttgaactaa gtttaaatac
    11341 tataccttat aaatatttta ctgagttttg tttattaaaa gcaactcaat ttctaaaagg
    11401 cacaaatgag ctaataagtg acattactat aaaagttgtt tttcatcaaa taatctattt
    11461 tagtaaatgt tttaaagaaa aaacgggata ttctccaaaa gtgtacagaa atataaaaaa
    11521 agagatatga ttttttattt cttttgatta tccaaagagt aaataaaaaa tattgtaaaa
    11581 aacttactaa caacggcaat gctttgaact atggtaatac tttgaacttt tgattggact
    11641 ttttttgcta aaataatata tttaaatagc aaagtaatct gtttaatcaa taaaaaataa
    11701 gagataaaag aaatcaacta aaacttttac ctcttatttt gatagtttat cagagctaat
    11761 atttacactc tttttatttt tgatacttca ttaaaaatga tgcttattct cttttcattt
    11821 ttaatacttc attagaactt atgcttattc tcttttcact tttaattctt cattagaact
    11881 tatgcttact ctccattcac ttttaattct tcattaaaaa tgatgcttac tctccattca
    11941 cttttaattc ttcattaaaa atgatgctta ttctccattc actttcaatt cttcattaaa
    12001 actgatgctt gcactctgta aactcataaa catccattaa tgcttcacca aatctttgat
    12061 agtgaactac ttccctctca cccaaaaatc tcaatatatc tttcaaatca gggtcatcag
    12121 ttaaatttat taattgatag tacgtagcca atgctttttg ttcagcagcc atatcctcat
    12181 gtaaatcagt taccgaatcg ccaaagacat taatataact tgtagtaaag tttactccat
    12241 tagaatctac tggctgaaga ccatgtccaa aattagcata attactacca agtccagcag
    12301 ccttaagctc ttctggagta caattgccta ttaattgata taacactgaa gaaattatct
    12361 caacatgagc catttcctct gtacctatat cagttaaaag tgcacgagat tttccagttg
    12421 gcatagtata tctttgttga agatatctag ttgcagctgc caactcacca ttaggtcctc
    12481 ccaactgagt catgatatat tttgccattc tagggtctgc ttgtcttatg ttaactggat
    12541 gttccagtgt tttttgataa atccacatat tatcttactc ctccttaata tatatttaat
    12601 aataaatcta attttaaagt ttaataattt tatttataaa atgatttgtc ccatggccaa
    12661 ggttcagata tccatgacca aggatattca cttgattcat atccaaaatt agttaatgct
    12721 ccatatttag attcataatc acacacagct tgtgtaaatt tatcgcagta tctgttgtat
    12781 gaatcaagag ctttcttatc ccttggattg ttatctaaat ataaatttaa ttctatacag
    12841 gcaaattgat attctgaaat tctctctaaa agttctcttc tatttaatga cattagtaca
    12901 tgttaccccc ttttttagct ctaactctat ttttaggatt tgcatatagc caatcattat
    12961 agttatttga ctctattaaa tctaattcag gaaataaagt acctcttttt aatgctgttt
    13021 ttggattgta tgtgtcatca taaatttgac gattgatgta tggtctagca aattcacaac
    13081 aatagtcttg tttatcctct tttaaatatc ccattaatta tcctccttaa tttttagaat
    13141 tttaaaatag cattattttt aaaaattgta tactggttct atattataac tggtagtttt
    13201 aataggtctt taataagatt aaatgattaa ataagtatct ttttttctta ttttacctct
    13261 aaaatttttc taattaatct ttcataaata tctattttaa ataaataata tagagtttat
    13321 acaattt
//
LOCUS       DAJMZY010000113        13276 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.114, whole genome shotgun sequence.
ACCESSION   DAJMZY010000113 DAJMZY010000000
VERSION     DAJMZY010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13276)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13276)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13276
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.114"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            536..1438
                     /locus_tag="OE968_003141"
     CDS             536..1438
                     /locus_tag="OE968_003141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCP7220398.1"
                     /translation="MSGIISVMTQSLILSIMALGVYITYKILDFPDMSADGSYTMGAS
                     IVAFSLTNGISPVVATLMAILCGCTAGLVTGILHIKFKISNLLSGILVMGMLYSINLR
                     IMGKSNIPLFSFKHLFNGEISPIVLALAFVFICKVLLDLFLKTGLGYTLKGVGDNSQM
                     IKSLGINIGSIKILGLMISNGLIALSGSLMAQFLGFSDVNMGIGTLVLGIASIIIGIT
                     LFKKFTFIKDTTAIIVGSFIYQFTIYFAMSLGMLSTDLKLITAIVIIAFLATGNLNIS
                     LKKNKCKASTKNKSEKRGVVDVTN"
     gene            1425..2180
                     /locus_tag="OE968_003142"
     CDS             1425..2180
                     /locus_tag="OE968_003142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003399531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCP7220399.1"
                     /translation="MLQIKNLSKSFPNPYGEPNTIFENLSIDIEDGEFVSIIGSNGTG
                     KSTLLNIISGLIKESSGQITLDSTTITNLAEYKRTQIVSRVFQDPSLGTCPSMTVREN
                     LSLALNKGKLLNLKKCLRHKTNDLEHLLEGISLDLKKYLDIKVQYLSGGQRQSLSLIM
                     SSLASPKVLLLDEHTAALDPKTSNEVIELTDKIVREKNITTLMVTHNLKHALQYGDRL
                     IMLHKGEVVLDVKDKEKKDLTVEEILEKFEYAV"
     gene            2277..3314
                     /locus_tag="OE968_003143"
     CDS             2277..3314
                     /locus_tag="OE968_003143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HCP7220400.1"
                     /translation="MIKSKKILSLIIAGVLGVSMLTGCSQNDGSNASNENKETDSKKQ
                     KNIGITQLVEHPSLDKAKKGFIKALEDKGYKDGDNIKIDFQNAQNDMPTTQSIASKFV
                     SDKKDLIYAISTPSAQAAYNATKDIPIIMTAVTDPVEAGLVKSLEKPGGNVSGTSDYL
                     SIDKTLELVKTLTPKAKKIGVIYNTSEVNSKIQVDSLHDYAKKNNYEVVEKGISSSSE
                     VNQAISSLVGKIDVLYVPTDNLIVSSMPIVSKVANENKIPIIASEEGSVSSGALACCG
                     IDYEKLGYKAGELAIEVLEGKSVGDIPVTTLDETEIIINEDTLKALDMQKLSADNIKY
                     IKSDENAKSTK"
     gene            4123..5025
                     /locus_tag="OE968_003144"
     CDS             4123..5025
                     /locus_tag="OE968_003144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCP7220401.1"
                     /translation="MSGIISVMTQSLILSIMALGVYITYKILDFPDMSADGSYTMGAS
                     IVAFSLTNGISPVVATLMAILCGCTAGLVTGILHIKFKISNLLSGILVMGMLYSINLR
                     IMGKSNIPLFSFKHLFNGEISPIVLALAFVFICKVLLDLFLKTGLGYTLKGVGDNSQM
                     IKSLGINIGSIKILGLMISNGLIALSGSLMAQFLGFSDVNMGIGTLVLGIASIIIGIT
                     LFKKFTFIKDTTAIIVGSFIYQFTIYFAMSLGMLSTDLKLITAIVIISFLATGNLNIS
                     LKKNKCKASTKNKSEKRGVVDVTN"
     gene            5012..5767
                     /locus_tag="OE968_003145"
     CDS             5012..5767
                     /locus_tag="OE968_003145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCP7220402.1"
                     /translation="MLQIKNLSKSFPNPYGEPNTIFENLSIDIEDGEFVSIIGSNGTG
                     KSTLLNIISGLIKESSGQVLLNKHNLSNLAEHRRTQIVSRVFQDPSLGTCPSMTVREN
                     LSLALNKGKLLNLRKCLRYKRDFLENLLEGVSLDLKKYLDVQVKFLSGGQRQSLSLIM
                     SCLTNPSVLLLDEHTAALDPKTSNEVIELTNKIVREKNITTLMVTHNLKHALHYGDRL
                     IMLHKGEVVLDVKGKEKEQLTVEEILEKFEYAV"
     gene            5898..6920
                     /locus_tag="OE968_003146"
     CDS             5898..6920
                     /locus_tag="OE968_003146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HCP7220403.1"
                     /translation="MINKKRLASLILAGALSISMLTGCSQGGDSGNSKQESNSKGKEV
                     KKIGITQLVEHPALDATRTGFVKALEKNGFKDGENIDIDFQNAQNDMPTTQSIASKFA
                     SDKKDLIFAISTPSAQAAFNATKDIPILITAVSDPVAAGLVKTLEKPGTNVSGTSDFV
                     SVDKGLELLKIFAPKAKTIGVMYNTSEVNSKVQVDALKEYASKNGFKVVEKGITTSNE
                     VNQGISSLVGKIDVLYVPTDNLVASSMPIVSKIATENKIPVIAAESGPVEKGALACQG
                     INYEKLGYKTGEMAVKILNGESVSDMPVATSDDTDIIVNEDILKALGMEKPSNENISY
                     VKTKQE"
     gene            complement(7084..7641)
                     /locus_tag="OE968_003147"
     CDS             complement(7084..7641)
                     /locus_tag="OE968_003147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HCP7220404.1"
                     /translation="MTEKEKMLSGKGYYANDELLVKEREYCKKLTRLFNNTLEDEYEK
                     REDILRQLFGSVGKQINVEQNIRCDYGYNIHVGENFFANYDCIFLDVCKIEIGDNVML
                     APNVQIYTAYHPIDAQLRNSGIEYGSPVKIGDNVWIGGGVIITPGITIGDNVVIGAGS
                     VVTKDIPPNTVAVGNPCRVIKKIEE"
     gene            complement(7647..8723)
                     /locus_tag="OE968_003148"
     CDS             complement(7647..8723)
                     /locus_tag="OE968_003148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate/molybdate ABC transporter ATP-binding
                     protein"
                     /protein_id="HCP7220405.1"
                     /translation="MSLYVDIEKDLSSFKLKVEIKQEKGTLGFLGESGSGKSMTLKCI
                     AGLEKPTRGKIVLNDRVLFDSEKKINLSTQDRKVGFLFQNYALFPHMTVSQNIELGLL
                     KLSKSEKKEIVARYLDILKLNGFEGRYPWQLSGGQQQRVALARALATSPDILLLDEPF
                     SALDHHLRSNMEKELMNMLKDYKGDILFVTHDIEEAYRVCDDIIVYNKGEGLPKRPKK
                     ELFESPKYLIEAKITGCKNISKLNRLDKNTIYATDWGCELTLNREIGDNIEYVGIREH
                     HIKVLDSNEDLNEKLCFELINIVENPFTYTIYVRKTDLSNECVPIQIELEKSKMRFKK
                     GDRIYLDFPQEYLFCFRYNYNKKE"
     gene            complement(8724..9407)
                     /gene="modB"
                     /locus_tag="OE968_003149"
     CDS             complement(8724..9407)
                     /gene="modB"
                     /locus_tag="OE968_003149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter permease subunit"
                     /protein_id="HCP7220406.1"
                     /translation="MGTDWSPLWISLKTSILSTIITFVIGIFVSYIMANYRGKWKGLI
                     DGLFTLPLILPPTVVGFFLLLLCGKNGFIGKFLLNFDRTLIFSWTATVISAVVVSFPM
                     MYRTSRSAFEQIDNNMLSAARTLGLNEWKVFFKIAVPLAWPGIIGGLVLSFARALGEF
                     GATLMIAGNIPGKTQTMPIAIFFAVEGGDMNKAMMWVMIIVAISIAMILLLNYWSEFQ
                     QKIIGKRCG"
     gene            complement(9556..10368)
                     /gene="modA"
                     /locus_tag="OE968_003150"
     CDS             complement(9556..10368)
                     /gene="modA"
                     /locus_tag="OE968_003150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter substrate-binding
                     protein"
                     /protein_id="HCP7220407.1"
                     /translation="MKKILGILGLVACLTLGTVGCNSNEDKKDDGKQEKTTKSSDSVE
                     LNISAAASLKEAMAKIEEEYKKVDSNVKLTVNYGASGSLQQQIEQGAPCDLFISAGQK
                     QMKALDEEKLLVSDTMKDLVKNDLVLISSADSSVSGMEDLTTDKVKKIAVGEAESVPA
                     GKYADEVLTNLNLKDKLKDKLVFAKDVKEVLAWVQSGNADVGFVYFSDTVNNDKIKVV
                     EKTDEKTHSPITYPVSVIKASKNVDAAKKFEEFLLSESGQKIFEEFGYKKVE"
     gene            10561..11490
                     /locus_tag="OE968_003151"
     CDS             10561..11490
                     /locus_tag="OE968_003151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCP7220408.1"
                     /translation="MDSLSSLTPVEVAELLKITKNTVYELIKRGELPSYKVGKKIRVD
                     TKDVEEYINSQKTGKVKDTHFNNKNIDINNNFKIIISGQDVILDILARSVEKKLDGIS
                     TFRSYIGSYNALYELYNGRVSIASSHLWDFETDEYNSTFVKKLLPGIPCVLINLAYRM
                     QGFYVAKGNPKEITTWEDLTKPSITIVNREKGSGTRVLLDGKLRLLNFNGKHIKGYDN
                     EELSHLGVASTVSRGIADVGLGNEKAALQVNNIDFIPLHKERYDLVIKKEDLQNPVYQ
                     TIINIINSPEFKAELQGLGGYDLTDTGKTIAKV"
     gene            complement(11651..12100)
                     /locus_tag="OE968_003152"
     CDS             complement(11651..12100)
                     /locus_tag="OE968_003152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220409.1"
                     /translation="MKNKNNKDKNMLNIKVLRVLGVLLILFDYTGDTLNFYNFFAKPL
                     VSGNLYKTTGTDCIVFLLFIVECVYLVGRYILKVKINWSEIIENEKGNFINNLLVEKI
                     QEESNIVYNLLNSYVLPNIYKKARGLMFKTYHMLIYIKEKYYYVNIY"
     gene            complement(12303..>13276)
                     /locus_tag="OE968_003153"
     CDS             complement(12303..>13276)
                     /locus_tag="OE968_003153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HCP7220410.1"
                     /translation="SFKNCISLRNKFIIISIVFLLILLIVSYIFGKLVYNSSVGLEQL
                     IKNEDIVKIFSERKDKPLEKLKNYKTSELMIQSSNNYKLESLFITSNIKTRDTMILVH
                     GIGSSYYEMLKVAYRYLDKGYNVLVYNQRNTGNSGGDNYTFGLYERYDLDSLVKFVKN
                     KFPEGRLGVHGFSMGAGTAAMHSEINSKDDKVDFYILDSPYSEMKDAIRMGVLEKRIP
                     DILINYVVTCGDLYNKFKSGFWYSDVKPYESVEKSNVPILFIHGTKDTVCNYQNSKKM
                     YDLVKHDKKDLWLIEGIGHVDGFEHDSTVYFNKIFKFIDSNVLSDKS"
BASE COUNT         4687 a         2017 c         1747 g         4825 t
ORIGIN      
        1 tatttttcat ttttataaaa aaacaataat taagaatata actatattct acatgtaaaa
       61 atttttttat ttaaactcaa ttttctgata atttgataat ttttcaaaat ttatagttga
      121 cttttatttt ttactgtatt aaactaatta ctatacaaaa cagaaaacaa aattttcaaa
      181 attattaaat taaaaggaga ggtaaatatg aagactttat taaacaaaca agtacgattt
      241 tttagtagcc aatttagtta gggtttgtac ctaagttaag acaaattgtc ataacataga
      301 tacaagcccc ttaggattat gatttttaag gattgtatct atgttggcta tagtaattgt
      361 tgttaaagtt tttattttat catcataata tagagccaca tggattatac tgtgtggctt
      421 attcgaattt ttgccataca gttatatata ctgtgtggtt tttttatatc aaaatcattt
      481 tttaaaacca aattttaaaa accatttaaa atattttcaa aggggtgttt tatttatgtc
      541 aggtattata tctgtaatga cgcaaagttt aattttatcg attatggcac tgggggttta
      601 tataacttac aaaatcttag attttccaga tatgtctgct gatggtagct atacaatggg
      661 tgcttctatt gtagcatttt ctcttactaa tggtatttct cctgtagtag caactttaat
      721 ggctatctta tgtggttgta ctgctggtct tgttacaggg attcttcaca ttaagtttaa
      781 gatatctaat ttactttctg gtattttagt tatgggaatg ctatactcta tcaatttaag
      841 aataatggga aaatcaaata ttcctctatt tagctttaaa cacttattca atggggaaat
      901 atctcctata gttttagcct tagcttttgt attcatctgt aaagtccttt tagatttatt
      961 cctaaaaaca ggtcttggat acactttaaa aggtgttggt gataactctc aaatgattaa
     1021 atctctaggt ataaatatag gttctataaa aatactagga cttatgattt caaatggact
     1081 tatagcttta tctggtagtc ttatggctca gttcttggga ttctcagatg taaatatggg
     1141 tataggaact ttagttcttg gaattgcctc tatcataatt ggtattacac tatttaagaa
     1201 atttactttt atcaaagata ctactgcaat aattgttggc tcttttatat accaattcac
     1261 tatatacttt gcaatgagtt taggaatgtt atcaactgac ttaaaactaa taactgccat
     1321 agttataata gctttcctag ctactggtaa cttaaatatt tcactaaaaa aaaacaaatg
     1381 caaagctagt accaaaaata aatcagaaaa aagaggtgtt gtagatgtta caaattaaaa
     1441 atctttcaaa gagtttccct aatccatatg gtgaacctaa tactatcttt gaaaatttat
     1501 caatcgatat agaagatggt gaatttgtaa gtatcatagg tagtaatgga actggtaaat
     1561 ctactttatt aaatataata tctgggctta taaaagaatc ttctggtcaa attactttag
     1621 atagtactac tataacaaat ttagctgagt ataaaagaac tcaaatagta agtagagttt
     1681 ttcaagaccc aagccttgga acttgtcctt ctatgacggt tagagaaaat ttatctctag
     1741 cacttaataa agggaaatta ttgaacttaa aaaaatgtct tcgtcataaa acgaatgact
     1801 tggaacactt acttgaagga atttctttgg atttaaaaaa atatttagat attaaagtac
     1861 aatatctttc agggggtcaa agacaatcac tatcactaat tatgtctagc ttagcaagtc
     1921 ctaaggtctt attactagac gaacatacag cagcacttga cccaaaaaca tcaaatgaag
     1981 taatagagtt aacagataaa atcgtaagag agaaaaatat aactacactt atggttactc
     2041 acaacttgaa acacgctctt caatatggag ataggttgat aatgcttcat aagggtgaag
     2101 ttgtattaga tgtaaaagat aaagaaaaaa aagatttaac agttgaagaa atcttagaaa
     2161 aatttgaata tgcagtataa gaaattaaaa tcttagtttt aatcagaaat atttataatc
     2221 tatcatatga atatatgaac aaatataatt attaaatttt aagggaggaa aataaaatga
     2281 taaaaagtaa aaaaatatta agtttaatta tagcaggagt acttggtgta tcaatgctta
     2341 ctggatgttc tcaaaatgat ggctccaatg cttcaaatga aaataaagaa acagatagca
     2401 aaaaacaaaa aaatataggt attactcaat tagtggaaca tccatctctg gataaagcaa
     2461 agaaaggatt catcaaagca cttgaagata aaggctataa agatggagat aatataaaaa
     2521 tagatttcca aaatgcacaa aatgatatgc ctactacaca aagtattgct agtaagtttg
     2581 tatccgacaa aaaagatttg atatatgcta tatctactcc atctgcacaa gcagcttata
     2641 atgctactaa agatattcca ataataatga ctgctgttac agaccctgta gaagctggac
     2701 ttgttaaatc tcttgaaaaa ccaggtggaa atgtttctgg tacatctgat tatctttcaa
     2761 ttgataaaac attagaattg gttaaaacat tgactccaaa agcaaagaaa ataggggtta
     2821 tatacaatac tagtgaagtt aattcaaaaa tccaagttga ttctctacat gattatgcta
     2881 agaaaaataa ttatgaagta gttgaaaaag gaatcagctc ttcaagtgaa gttaaccaag
     2941 ctatttctag tttagttggt aaaatagatg ttttatatgt ccctactgac aatttaatag
     3001 tttcttctat gccaatagtt tctaaagttg ctaatgaaaa caagattcct ataatagcct
     3061 ctgaagaagg ttctgtatct tctggtgctt tagcttgttg tggaatagat tatgaaaaac
     3121 taggttataa ggctggagaa cttgctattg aagtattaga aggaaaatct gttggcgata
     3181 taccagttac tacattagat gaaactgaaa taataattaa cgaagataca ctaaaagcac
     3241 ttgacatgca aaagttatca gcagataata taaagtatat aaagtcagat gaaaatgcaa
     3301 aatctacaaa ataaaactta ttaatttcaa aaaataggta atatgaagta ggtaatatga
     3361 aaactttata taataagtac tcttatccac cctaaccctt tgaaaattgt gcttattgta
     3421 gcaatttgaa tattgcatat aaagttattc attttccata aaagtcgtct atattgacga
     3481 ctgattatga aagttatata actttctaat cactacttga gctgtccaaa agaattttaa
     3541 tattctccag acagcttttt tttatgatat ttgattgata tacatgtcta gttattccat
     3601 atttagtaaa tattttgata aaatttccac attcacttat aacttaggat aacgtttttt
     3661 tcaaacaata cattaattta aaagtattct gagtatacat tatttagtat tttaattaaa
     3721 tttagcagtt gacttttatt attgtataat ttataattta taacaagtcg agaatacata
     3781 taattttctg actaattaaa atattaaaag ggagagataa ttatgaatac tttattaaac
     3841 aatagaaaat attattatta ttatagccac tatttttagg gtttgtacct acgttttaac
     3901 atagatacag accccttaag actactaaaa ttttgggatt gtatctatgt tggctatatt
     3961 gtttataaag ttttcattta actatataag agccacatag attaaactat gtggcttatt
     4021 cgtgttttta ccacatagtt ttgtacacta tgtggttttt ttatacacaa aattagcaaa
     4081 taattaaaat tataaaaata ttttcaaagg agtgttttat ttatgtcagg tattatatct
     4141 gtaatgacgc aaagtttaat tttatcgatt atggcactgg gggtttatat aacttacaaa
     4201 atcttagatt ttccagatat gtctgctgat ggtagctaca caatgggtgc ttctattgta
     4261 gcattttctc ttactaatgg tatttctcct gtagtagcaa ctttaatggc tatcttatgt
     4321 ggttgtactg ctggtcttgt tacagggatt cttcacatta agtttaagat atctaactta
     4381 ctttctggta ttttagttat gggaatgcta tactctatca atttaagaat aatgggaaaa
     4441 tcaaatattc ctctatttag ctttaaacac ttattcaatg gggaaatatc tcctatagtt
     4501 ttagccttag cttttgtatt catctgtaaa gtccttttag atttattcct aaaaacaggt
     4561 cttggataca ctttaaaagg tgttggtgat aactctcaaa tgattaaatc cctaggtata
     4621 aatatcggtt ctataaaaat actaggactt atgatttcaa acggacttat agctttatct
     4681 ggtagtctta tggctcagtt cttgggattc tcagatgtaa atatgggtat aggaacttta
     4741 gttcttggaa ttgcctctat cataattggt attacactat ttaagaaatt tacttttatc
     4801 aaagatacta ctgcaataat tgttggctct tttatatacc aattcactat atactttgca
     4861 atgagtttag gaatgttatc aactgactta aaactaataa ctgccatagt tataatatct
     4921 ttcctagcta ctggtaactt aaatatttca ctaaaaaaaa acaaatgcaa agctagtacc
     4981 aaaaataaat cagaaaaaag aggtgttgta gatgttacaa attaaaaatc tttcaaagag
     5041 cttccctaat ccatatggtg aacctaatac tatctttgaa aatttatcaa tcgatataga
     5101 agatggtgaa tttgtaagta tcataggtag taatggaact ggtaaatcta ctttattaaa
     5161 tataatatcc gggcttataa aagaatcttc tggtcaagta ttattaaata aacataactt
     5221 gtctaattta gctgaacaca gaagaactca aatagtaagt agagtttttc aagacccaag
     5281 tcttggaact tgcccttcta tgactgttag agaaaacttg tctttagctc ttaacaaagg
     5341 aaaactatta aatctaagaa aatgtcttcg ttacaaaaga gatttcttag aaaatttatt
     5401 ggaaggtgta tctcttgatt taaaaaaata ccttgatgtt caagtaaaat ttttatcagg
     5461 aggtcaaaga caatcattat cactaattat gtcgtgctta acaaatccat cagttttatt
     5521 acttgatgaa catacagcag cacttgaccc aaaaacatca aatgaagtaa ttgaattgac
     5581 taataagatt gtaagggaaa aaaatataac tacacttatg gttactcaca acttaaaaca
     5641 cgctcttcat tatggtgata gattgataat gcttcataag ggtgaagttg tattagatgt
     5701 aaaaggtaaa gaaaaagaac aattaacagt tgaagaaatc ttagaaaaat ttgaatatgc
     5761 agtttaaaat aatatatcta ttgtattaaa ctcggcttta aaataaagtt aaaattacaa
     5821 taattatggt tactttgtaa taattcatat gaatatatga acatatataa taataaattt
     5881 ttgaggggga tataaaaatg attaataaaa aaagattggc aagtttgatt ttagctggtg
     5941 ctcttagtat atctatgctt acagggtgtt cacaaggagg agactctggt aattcaaaac
     6001 aagaaagtaa ttctaaaggt aaagaagtta aaaaaattgg tataactcaa ctggttgaac
     6061 atccagcatt agatgccact aggacaggtt ttgtaaaagc attagaaaag aacggattta
     6121 aagatggaga aaatattgat atagacttcc aaaatgctca aaatgacatg cctactacac
     6181 aaagtattgc gagtaaattt gcatctgata agaaggactt aatatttgct atatctactc
     6241 catcagctca ggcagcattt aatgctacta aagatatacc tatacttatt actgctgtga
     6301 gtgaccctgt tgctgctgga ttagttaaaa ctcttgaaaa gccaggcaca aatgtatctg
     6361 gaacatcaga ttttgtttct gtagacaaag gtttagaact tcttaaaata tttgctccta
     6421 aggcaaaaac tataggagtt atgtacaata ctagtgaagt aaattccaaa gtccaagttg
     6481 atgctttaaa agaatatgca tctaaaaatg gatttaaagt tgttgaaaaa ggtataacta
     6541 cttcaaatga agttaaccaa ggtatttcta gtttagttgg caaaatagac gtattatatg
     6601 ttcctacaga taacttagtg gcttcttcta tgcctatagt ctctaaaata gctactgaga
     6661 ataaaatacc tgttatagca gctgaatctg ggccagttga aaaaggtgct cttgcttgtc
     6721 aaggtatcaa ctacgaaaaa ctaggttaca aaacaggtga aatggcagtt aaaattttaa
     6781 atggtgaatc agtatctgat atgcctgtgg ctacatcaga tgatacagat atcattgtta
     6841 atgaagatat attaaaagct ttaggtatgg aaaaaccttc taatgaaaat atttcttatg
     6901 taaagactaa acaagaatag aaagatattt tctatatacg attaatatgc ctgtttctat
     6961 aaattaattt atagaaacag gcatatattt ttattttaat gtattatcta tttaaagatt
     7021 atatgtaaat gctcttaatt tgtttgtata aattttactt gtataaactt tatacaatca
     7081 tatttattct tctattttct ttattactct acatggattt ccaacagcta cagtatttgg
     7141 tggtatatct tttgtgacta cacttcctgc acctattact acattatcac ctatagtaat
     7201 tcctggtgtt atgattactc ccccacctat ccatacatta tcacctattt ttacaggaga
     7261 accatactct atacctgaat ttctaagttg tgcatcaatt ggatgatagg ctgtatagat
     7321 ttgaacgttt ggagctaaca ttacattgtc acctatttca attttacata catctaaaaa
     7381 aatacaatca taatttgcaa agaaattttc gcctacatgt atgttatatc cataatcaca
     7441 cctaatattt tgttctacat ttatttgctt gccaactgaa ccaaatagtt gtcttaaaat
     7501 atcttctctt ttttcatatt catcctctaa agtattatta aacaatctag ttaatttttt
     7561 acaatactct ctttctttta ctaacaattc atcatttgca tagtatcctt tcccagacaa
     7621 cattttttct ttttcagtca tatagtttac tcctttttgt tataattgta tctaaagcaa
     7681 aataaatatt cctgtggaaa atctaaatat attctgtcac ctttcttaaa tctcatttta
     7741 cttttttcca attctatttg aataggtaca cattcgttag ataaatcagt ttttctaaca
     7801 tatatagtat atgtaaaagg attttctaca atgttaatca attcgaaaca taacttttca
     7861 tttaaatctt cattagaatc caagacctta atatgatgct ccctgattcc cacatattct
     7921 atattatcac ctatttctct atttaatgtc aactcgcatc cccagtctgt agcataaata
     7981 gtatttttat ccagtctatt taatttggat atatttttac accctgttat cttagcttct
     8041 ataaggtact ttggagattc aaagagctct tttttaggtc tctttggaag accttctcct
     8101 ttgttgtaca ctataatatc atcacaaact cggtaagctt cttcaatatc atgagtaaca
     8161 aatagtatat ctcccttgta atcttttaac atattcataa gttctttttc catattgctt
     8221 cttaaatgat ggtccaatgc tgagaaaggt tcatctaaaa gtaatatatc tggagatgtt
     8281 gccaatgctc tagctagtgc taccctttgt tgttgaccac cagataattg ccaagggtat
     8341 ctcccctcaa acccatttaa tttaagtata tctaagtacc ttgctactat ttcctttttt
     8401 tcactcttac ttagttttaa aagcccaagt tctatatttt gacttacagt catatgtgga
     8461 aacaaagcat agttttgaaa taaaaatcct acctttctat cttgtgttga taaatttatc
     8521 ttcttttcag aatcaaatag aactctatca tttaatacaa ttttacctct tgttggtttc
     8581 tcaagccctg ctatacattt taatgtcata ctttttccag aaccagattc tcccaaaaac
     8641 cccagagtac ctttttcttg tttaatttct acctttagtt taaaagagga taaatctttt
     8701 tcaatatcca cgtataagct caactatcca cacctctttc ctataatttt ctgctgaaat
     8761 tccgaccaat aatttagtaa taaaatcatt gctatagata ttgctacaat aatcataacc
     8821 cacatcatag ctttattcat atctccgcct tcaacagcaa aaaatatagc tattggcata
     8881 gtttgagttt ttccaggtat atttccagct atcataagtg tagcaccaaa ttctccaaga
     8941 gctctggcaa acgacagcac caatccacca attattccag gccatgctaa tggaactgca
     9001 atcttaaaaa atactttcca ttcattaaga cctaatgttc tagcagctga caacatatta
     9061 ttatcaatct gttcaaaagc tgaccttgaa gttctataca tcataggaaa agacaccact
     9121 actgctgaaa ttacagttgc tgtccaacta aatattaaag tcctatcgaa atttaataaa
     9181 aactttccta taaatccatt cttcccacat agtaataata aaaagaaacc tacaactgtt
     9241 ggtggcaaaa ttagtggaag tgtaaatagt ccatctataa gacccttcca cttacctcta
     9301 tagttagcca taatatatga cacaaatatt cctattacaa aagttattat tgttgacaaa
     9361 atagatgtct taagtgatat ccataagggt gaccaatctg ttcccatctt tccctcctta
     9421 attttaaatg gaaatagtga aactaataac tctattaatt tcactatttc cattttatta
     9481 taatacacaa ttattttcaa ttttcattta tttatatata atttatactt aattacacat
     9541 aatttatttc taagtttatt ctactttttt atatccaaat tcttcaaaaa tcttttgtcc
     9601 tgactcactt aataaaaatt cttcaaattt cttagcagca tctacgtttt tactagcttt
     9661 aattactgaa actggatatg taataggcga atgagttttt tcgtctgttt tttcaactac
     9721 ttttatctta tcattattga cagtatcact gaagtaaacg aatccaacat cagcatttcc
     9781 tgattgcacc catgctaaaa cttcttttac atcttttgca aatactagct tatcttttaa
     9841 cttatctttt aaatttaaat tagttaacac ctcatctgca tacttaccag ctggaacact
     9901 ttcagcttca ccaacagcaa ttttcttcac tttatctgta gtcaaatctt ccatacctga
     9961 tacactactg tcagcagaag aaataagaac taaatcattt tttactaaat ctttcatagt
    10021 atcagaaact aataacttct cttcatccaa agctttcatt tgtttttgac ctgctgaaat
    10081 aaataaatca caaggtgctc cttgttctat ttgttgttgt aatgagcctg atgctccata
    10141 gttaactgta agttttacat ttgaatcaac ttttttatat tcttcttcaa tctttgccat
    10201 tgcttctttt aaacttgcag cagccgatat atttaactct actgaatcac tacttttagt
    10261 tgttttttct tgttttccat catctttttt gtcttcatta ctattgcacc caactgtccc
    10321 caaagttaaa catgcaacta atcctaatat tcccaatatt tttttcataa caatctccct
    10381 ttttgtaaat ttgatacaca ttttaacatg ttttattatg ttttatcatg ttttgttata
    10441 tatagtttaa ttatatatac atgataataa attttcaagt aatttattta cactactttt
    10501 aaatattttg ctacattttc ctttttttaa tgttaaaata accttatatg gaggtggatt
    10561 atggactcat tatcatcttt gacacctgtc gaggtagctg aattattaaa gataacaaaa
    10621 aatactgtat atgaattaat caaaagaggt gaacttcctt cttataaagt agggaaaaaa
    10681 ataagagttg atactaaaga tgttgaagaa tatatcaaca gccaaaaaac tggtaaagta
    10741 aaggatacac atttcaacaa taaaaatata gatataaata ataatttcaa aattattatt
    10801 tctggtcaag atgtaatatt agacatttta gctaggtctg ttgaaaaaaa attggatgga
    10861 ataagtacat ttcgctctta tataggtagt tataatgctt tgtatgagtt atataatggc
    10921 agagtttcta tagcatcatc ccatctatgg gatttcgaaa cggatgaata taatagcact
    10981 tttgttaaaa agctattgcc aggaatacca tgtgtactta taaatctagc ttatagaatg
    11041 caaggtttct atgttgctaa aggaaatcct aaagagataa caacctggga ggatttaaca
    11101 aaaccaagta taaccattgt aaatagggaa aaaggttctg gaactagggt tttactagat
    11161 ggtaaactta gacttctaaa ctttaatggt aaacatataa aaggttatga taatgaagaa
    11221 ttatcacatc ttggagttgc aagtactgtt tctcgtggaa tagcagatgt tggtttggga
    11281 aatgaaaaag ctgctttaca agtaaataat atcgacttta ttcctcttca caaagagcgc
    11341 tatgatttag ttattaaaaa agaagactta caaaatccag tttaccaaac tataattaac
    11401 ataataaact ctcctgagtt taaagctgaa cttcaaggtc ttggcggata tgatttaact
    11461 gatactggaa aaactatagc aaaagtttaa gattaaaatc gcaatctatt ttataagatt
    11521 tataattttt cacaaaattt ataacttaaa cacgaaataa attgcgattt tagtgtctca
    11581 aaaaatttat gtctttcatt ttatcatcca atacaaaata taatataatt aattgtgcaa
    11641 tcatattata ttaatatata tttacataat agtatttttc tttaatgtag attaacatat
    11701 gatatgtttt aaacatcaat ccccttgctt tcttatatat atttggcaac acatatgagt
    11761 ttaataaatt atatacaatg ttgctttctt cttgtatttt ttcaaccaac aagttattta
    11821 taaaattacc tttctcattt tcaataatct cactccaatt tatcttaact tttaatatat
    11881 atcttcccac taggtataca cactctacaa taaataataa aaatacaatg cagtcagtac
    11941 ctgttgtctt atataaatta cccgatacta atggctttgc gaagaaatta taaaaattca
    12001 aagtatcacc cgtataatca aaaagtatta atagcactcc tagaactctc aatactttaa
    12061 tattcaacat gtttttatct ttattatttt tgtttttcat atatactacc tctcttttct
    12121 ttagatttga ttgtaatcta atactaactc ttttatttga ggtataaatg aatttaattg
    12181 gtagttattt tcatttttac tagaaattaa ttcacattac taaacaaaac ttatatttaa
    12241 acataaaaat agcctatcta tcttttaata aatacaaaaa taaataagct actaatattc
    12301 aattaacttt tatcacttaa aacattacta tctataaatt taaatatttt attgaagtat
    12361 actgtactat catgttcaaa tccatcaaca tgaccaatac cttctataag ccataggtct
    12421 tttttatcat gtttaactaa atcatacatt ttcttgctat tttgataatt acaaacagta
    12481 tcttttgttc catgtataaa cagtatgggt acattagatt tctcaactga ctcatatggt
    12541 tttacatcac tgtaccaaaa tccagattta aacttattat ataaatctcc acaagtcacc
    12601 acataattga ttaatatatc tggtattcgt ttttctagta ctcccattct aattgcatct
    12661 ttcatttcag aataaggaga atccagtata taaaaatcga ccttatcatc ttttgaattt
    12721 atctctgaat gcatagcagc tgtccctgcc cccatggaaa atccatgcac acctaatctc
    12781 ccttcaggaa atttattttt tacaaattta actagactat ctaaatcata cctttcataa
    12841 agaccaaatg tgtaattatc tccaccacta ttaccagtat ttctttgatt ataaactaat
    12901 acattataac ctttatctaa atatctatat gctaccttta acatttcata gtaactactt
    12961 ccaattccat gaacaagtat catagtatct cttgtcttta tatttgaagt tataaaaaga
    13021 ctttcaagct tgtaattatt agaactttgt atcattaatt cagatgtctt gtagtttttt
    13081 aatttctcca gtggtttatc ttttctctca gaaaatattt ttactatatc ttcgtttttt
    13141 attaactgct ctaaaccaac tgaactatta tacactaatt ttccaaatat ataagataca
    13201 attaatagga ttaatagaaa cacaattgat ataattataa atttatttct taaactaata
    13261 caatttttaa aactat
//
LOCUS       DAJMZY010000114        13137 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.115, whole genome shotgun sequence.
ACCESSION   DAJMZY010000114 DAJMZY010000000
VERSION     DAJMZY010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13137)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13137)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13137
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.115"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            <1..196
                     /locus_tag="OE968_003154"
     rRNA            <1..196
                     /locus_tag="OE968_003154"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            324..440
                     /gene="rrf"
                     /locus_tag="OE968_003155"
     rRNA            324..440
                     /gene="rrf"
                     /locus_tag="OE968_003155"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            448..522
                     /locus_tag="OE968_003156"
     tRNA            448..522
                     /locus_tag="OE968_003156"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:480..482,aa:Asn,seq:gtt)
     gene            528..613
                     /locus_tag="OE968_003157"
     tRNA            528..613
                     /locus_tag="OE968_003157"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:562..564,aa:Leu,seq:taa)
     gene            629..704
                     /locus_tag="OE968_003158"
     tRNA            629..704
                     /locus_tag="OE968_003158"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:662..664,aa:Met,seq:cat)
     gene            712..786
                     /locus_tag="OE968_003159"
     tRNA            712..786
                     /locus_tag="OE968_003159"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:745..747,aa:Glu,seq:ttc)
     gene            801..874
                     /locus_tag="OE968_003160"
     tRNA            801..874
                     /locus_tag="OE968_003160"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:833..835,aa:Gly,seq:tcc)
     gene            880..955
                     /locus_tag="OE968_003161"
     tRNA            880..955
                     /locus_tag="OE968_003161"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:913..915,aa:Val,seq:tac)
     gene            961..1037
                     /locus_tag="OE968_003162"
     tRNA            961..1037
                     /locus_tag="OE968_003162"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:995..997,aa:Asp,seq:gtc)
     gene            1048..1122
                     /locus_tag="OE968_003163"
     tRNA            1048..1122
                     /locus_tag="OE968_003163"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1080..1082,aa:Gly,seq:gcc)
     gene            1132..1205
                     /locus_tag="OE968_003164"
     tRNA            1132..1205
                     /locus_tag="OE968_003164"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1166..1168,aa:Arg,seq:tct)
     gene            2189..3028
                     /locus_tag="OE968_003165"
     CDS             2189..3028
                     /locus_tag="OE968_003165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HCP7220411.1"
                     /translation="MLDINSFLNGFFNIILRMSIYDLIDISIVAYIFYKIFMFIKDTR
                     AEQVFKGIIFLLLATQLSNTFKLHTVYWISLKALDYGVIAALIIFQPEFRAGLEHIGR
                     AKFNLFGKNVNTSEETLNRNIEEIVEALYSLSRQKIGALIIMERETRISDIINTGTII
                     DAEISRQLLINIFIPNTPLHDGAVVIRDSKVKAAACFLPLTESKDLSKDLGTRHRAGI
                     GVSEVSDCITLIVSEETGGVSIAKAGKLYRDISRERMMNILRSNLKTNTETRSFFKGG
                     IFK"
     gene            3025..4206
                     /locus_tag="OE968_003166"
     CDS             3025..4206
                     /locus_tag="OE968_003166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220412.1"
                     /translation="MINRLKNNTKIKIISFLSAIALWMYVMAVVDPEETKGFEDIPVS
                     ISNMSDLKDKNLVIYPDEKLTADVYIKGSLSKVQSVKKEDIHVYGTIEDPIQGQKEVY
                     LKANIPQGVTLEFKHDVLVVNLEKNIKEKRDIKVEVSGNSKRNINKIELSKEFVDVSG
                     PRTLVKEVKSVRANLDVGNETDDFSKKLQLIPLNSDGTKVEGVTLSSSFVTAKIELLK
                     EKIVPIRVSLNDNKDNDVLKNYKLSKEQVTIKGKKEDIDKISYIKTKPIDLADLANGE
                     EKEVSLEIPEGITLEDSSITIKLNDTKQLSAEFLYNAGDIELRNIPTNMDNPNVISDV
                     DIKVVVESTEDLSKLNKKDISLYIDLSQGPEEDSKYKIKYETTYQFKKINIEPNIVEV
                     E"
     gene            4510..5412
                     /gene="ptb"
                     /locus_tag="OE968_003167"
     CDS             4510..5412
                     /gene="ptb"
                     /locus_tag="OE968_003167"
                     /EC_number="2.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate butyryltransferase"
                     /protein_id="HCP7220413.1"
                     /translation="MRSFEEVIKFAKERGPKTISVACCQDKEVLMAVEMARKEKIANA
                     ILVGDIEKTKEIAKSIDMDIENYELIDIKDLAEASLKSVELVSQGKADMVMKGLVDTS
                     IILKAVLNKEVGLRTGNVLSHVAVFDVEGYDRLFFVTDAAMNLAPDTNTKKQIIENAC
                     TVAHSLDISEPKVAAICAKEKVNPKMKDTVEAKELEEMYERGEIKGCMVGGPFAIDNA
                     VSLEAAKHKGINHPVAGRADILLAPDIEGGNILYKALVFFSKSKNAGVIVGAKAPIIL
                     TSRADSEETKLNSIALGVLMAAKA"
     gene            5434..6513
                     /gene="buk"
                     /locus_tag="OE968_003168"
     CDS             5434..6513
                     /gene="buk"
                     /locus_tag="OE968_003168"
                     /EC_number="2.7.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="butyrate kinase"
                     /protein_id="HCP7220414.1"
                     /translation="MSKIFKILTINPGSTSTKIAVFDNEDLVFEKTLRHSSEEIGKYE
                     KVSDQFEFRKQVIEEALKEGGVKTSELDAVVGRGGLLKPIKGGTYSVSAAMIEDLKVG
                     VLGEHASNLGGIIAKQIGEEVNVPSYIVDPVVVDELEDVARISGMPEISRASVVHALN
                     QKAIARRYAREINKKYEDINLIVAHMGGGVSVGAHKNGKIVDVANALDGEGPFSPERS
                     GGLPVGALVKMCFSGKYTQDEIKKKIKGNGGLVAYLNTNDAREVEERIEAGDEKAKLV
                     YEAMAYQISKEIGASAAVLKGDVKAILLTGGIAYSKMFTEMIADRVKFIADVKVYPGE
                     DEMIALAQGGLRVLTGEEEAQVYDN"
     gene            6503..7180
                     /locus_tag="OE968_003169"
     CDS             6503..7180
                     /locus_tag="OE968_003169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HCP7220415.1"
                     /translation="MITNDKRIRIITGHYGSGKSEFAMNYVVKLRDMVSGKVAIADLD
                     VVNVYFRTREKKELMKSLGIQPIDSSINAPTLDLPAVSAEVMSPMVDHSYNSVIDLGG
                     DNVGARVIGRFSHLLKEGDYDMLFVINANREKTQTSEEVIQYIKEIEKSSKLKVTGLI
                     NNTHLIRFTTIDDVLRGQKVAKEVSEKCNIPIRYVACLENLVEQLPKDLEGEIFPIKL
                     YMREDWM"
     gene            7223..7438
                     /locus_tag="OE968_003170"
     CDS             7223..7438
                     /locus_tag="OE968_003170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HCP7220416.1"
                     /translation="MAKGKVSFNQERCKGCGLCVEACPVKIIQLDSNVINKKGYNPAT
                     VFEMEKCIGCASCATMCPDVVITVERD"
     gene            7467..8546
                     /locus_tag="OE968_003171"
     CDS             7467..8546
                     /locus_tag="OE968_003171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate dehydrogenase subunit
                     VorB"
                     /protein_id="HCP7220417.1"
                     /translation="MAKILMKGNEAFGKAAIEAGCKYFFGYPITPQSELPEYLSRELP
                     KIGGAFVQAESEVSAINMVYGGAGAGARVMTSSSSPGVALKQEGITYAVGAEVPCVVL
                     NVMRGGPGLGSIQPSQADYFMSTRGGGNGDYRTPVFAPATVQEAVDMIMEAFDVADYY
                     RSPVMVVADGMIGQMMEPVEFRAPEKKRELPPKDWATVGTKGKRKPNVINSLYLEPEV
                     LEDHCWHLQEKFDAMEKNEVQYEMYKTEDAEFVFAAYGTTSRVVKSAIDILREEGIKA
                     GLIRPKVLWPFPFEAFNQIPNARNILTVEMSMGQMVEDVKMAVEGKLPVYFHGRPGGM
                     TPTPAEIVEKAKKIIAGELVAGGAR"
     gene            8546..9298
                     /locus_tag="OE968_003172"
     CDS             8546..9298
                     /locus_tag="OE968_003172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate oxidoreductase"
                     /protein_id="HCP7220418.1"
                     /translation="MAVVFKKTEGLQDTQTHYCPGCTHGIIHRLVGEVLEELGVLGDA
                     VGVVPVGCSVLGYKYFNCDTQEAAHGRAPAAATGIKRVHPENTVFTYQGDGDLASIGT
                     AEIVHAAARGEKITTIFVNNTTYGMTGGQMAPTTLVGQRATTAQSGRNAETQGYPIRV
                     SEMLATLTGAVFVERVAVDTPAHVRQAKKAIKKAFQVQQAGLGFGIVEVLSTCPTNWG
                     LAPNDALQWLRDNMIPYYPLGNFKNVEVEEVK"
     gene            9299..9856
                     /locus_tag="OE968_003173"
     CDS             9299..9856
                     /locus_tag="OE968_003173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoacid:acceptor oxidoreductase family
                     protein"
                     /protein_id="HCP7220419.1"
                     /translation="MSTARVICAGFGGQGVMSMGQLLTYAGMLEGKEVSWLPSYGPEM
                     RGGTANCAVTVSNEPVGSPLITDDATAAILLNIPAFEKFKDDVIPGGKIIVNSSLIKE
                     KVDRTDVDVYYIPANELAAELGNDKVANMIMLGAYLKVSDTVDIESVLEAFKKVFGPR
                     KEKFVPLNREALQKGMDATCSKATN"
     gene            10026..11372
                     /locus_tag="OE968_003174"
     CDS             10026..11372
                     /locus_tag="OE968_003174"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HCP7220420.1"
                     /translation="MRKYFGTDGVRGVANTELTCDLAYKLGRAGGFVLAQGDHRVKVV
                     VGKDTRISGDMLEASLIAGLMSVGCDVITVGIIPTPAVAYLTRKYGADCGVVISASHN
                     PVEYNGIKFFNKNGYKLDDEIELKIEEYIDDIDKIDCLPIGENVGRKLHEHCAQRDYV
                     DYLKSIISTDFKGLKVVLDCANGASYKVAPIVFDELGASVISINSSPDGNNINYKCGS
                     THPEQLQRAVLEHNADLGLAYDGDADRLIAVNEKGQIVDGDHIMILSALNLKKNNKLA
                     QDTLVVTVMSNIGLTIAAKENGINLSTTAVGDRYVLEDMVKNGYNLGGEQSGHMIFLD
                     YNTTGDGVLSSLILANIILQEKKPLSEIASIMSQYPQVLVNATIKNENKNKYMEYPEI
                     KTEIERIESILDGNGRVLIRPSGTEPLVRVMLEGKEEGQIKELATNLANLIQEKLS"
     gene            11639..>13137
                     /gene="glmS"
                     /locus_tag="OE968_003175"
     CDS             11639..>13137
                     /gene="glmS"
                     /locus_tag="OE968_003175"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003401499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HCP7220421.1"
                     /translation="MCGIVGYLGSRKAAEVIVEGLSKLEYRGYDSAGVAVNSSNEKEL
                     NIRKFKGRLSVLAEDLEKNPIDGNLGIGHTRWATHGEPSDVNSHPHFNQAKTIAVVHN
                     GIIENYMEIKEELISEGVKFESQTDTEVIAHLVDKYYEGNLLDAVYKTISKLRGAYAL
                     GVICKEHGNELVAVRKDSPLVVGVGEGENFIASDIPALLKYTRDVYFLENGEVVHLKD
                     ENVTVYDSNRNLVEKEVFHVTWDVEAASKGGYDYFMSKEIHEQPTGVRETLERRLDDN
                     GNIILDSINISKEDLEKINKVYIVACGTAYNAGLLGKYAIEKFVNIPVITDIASEFRY
                     SDPFVDENSLVILVSQSGETADTLAVLRDSKAKGARILSITNVVGSSIARESDDVFYT
                     WAGPEVAVASTKAYTTQITSLYMIALDFAIKKGTITREFYDSMISKMKEIPSKIQEIL
                     DNEEYIKEVAKTVVSSEHAFYLGRGIDYSLAMEGSLKLKEISYIHAEAFA"
BASE COUNT         5032 a         1618 c         2647 g         3840 t
ORIGIN      
        1 ctgccaaggg catggctggg tagctatgta cggaatggat aagcgctgaa agcatctaag
       61 cgcgaagcca acttcaagat aagatttccc accgcaaggg taagacccca gaaagactat
      121 ctggttgata ggtcgaaggt gtaagtgcag caatgtattt agcttatcga tactaatagg
      181 tcgaggactt gaccaatatt tatttgatgt tcattcatta agatatatgt gtagttttta
      241 gagtgctaac tctaaagaaa ctagtattgc taggttctat aaacttatta aaaacttaat
      301 agaaatatta agcataaaga ttatgtggtt acaatagcag agaggataca cctgttccca
      361 tttcgaacac agaagttaag ctccctagcg ctgatggtac ttggtgggaa actgcctggg
      421 agagtaggac gtagccacgt taaatgttcc aaggtagctc aacggtggag caaccggctg
      481 ttaaccggta ggctgtgggt tcgagcccca cccttggagc caaaaaagcc gaagtggcgg
      541 aactggcaga cgcacaggac ttaaaatcct gcgggactta cctctcgtac cggttcgatt
      601 ccggtcttcg gcacttataa aacaatatcg cggggtggag cagttggcag ctcgtcgggc
      661 tcataacccg aaggtcgtag gttcaagtcc tgcctccgca accattaaaa cggctcgttg
      721 gtcaagaggt taagacaccg ccctttcacg gcggtaacag gggttcaatt cccctacgag
      781 tcaccaattc aattaaatat gcgggtgtag ctcaatggta gagttctggc cttccaagcc
      841 agctgtgagg gttcgatccc cttcacccgc tccaaaaatg ggaccatagc tcagctggga
      901 gagcacctgc cttacaagca gggggtcaca ggttcgagcc ctgttggtcc caccattcgc
      961 ggcctggtag ttcagttggt tagaatgcca gcctgtcacg ctggaggtcg agggttcgag
     1021 ccccttccag gtcgccaaat taaataagcg ggaatagttc agtggtagag cgcaaccttg
     1081 ccaaggttga agtcgcgagt tcgaatctcg tttcccgctc cataataact tgggtgcata
     1141 gctcagctgg atagagcaac gcccttctaa ggcgtgtgtc cggggttcga atccctgtgc
     1201 gctcattaag aaaagtttac tataaattat agtaaacttt tatattgttt aaaaagacac
     1261 aggaaacatg tatattacct gtgtcttttt atttataaac tttaaactat gtaaaaatta
     1321 cagtatattc taatagagtt acagtatatt cattaatatt gtaaacatac ggagggtaat
     1381 gtataatagt ctacaagatg tttatgaagg catcagttaa atataataaa tataactaat
     1441 tagtaagagt tatatacatt atattgtata ctttatggta tttatatatt gaaataactt
     1501 atgaaattat ttataaagag attcatgagc atatttttgt ctaaacaata agtataagaa
     1561 attataaaaa gttagagact atagtgaatt tacaatttaa tgtaatattt ataagttata
     1621 ctaaataaat tattatactg tgaaatggat atataacttt aggtattgtg tattattttc
     1681 actgtaggag attatatcta gttatacata ataagtttta atgatagttt atagtaagat
     1741 attaaaataa atttatctaa tctagatatg aaataagtta ttactttaat ataaaaatga
     1801 atctaatgga ataatattga tgataagtaa tatttagatt ttgtatttgt ttatagttaa
     1861 taagtggatt atagaattta taataattaa tatatattaa acaaagatat attaagatat
     1921 tttagaacat aaaactgaat taaggcgcga gtactatttt gtattcgcgc cttgatggtt
     1981 tgagttattt gagtaaaaac taactttaat aagaaatatg tatttattaa gttgatattt
     2041 ttaatgtgtt tagagattat ttaacaatct ccaaatataa aactagaatt atttacataa
     2101 aagttaaata gtttgtatag agttagattt atatagtata atacttagtg taaataatta
     2161 agaagttatc aaacaggagg ataaaactgt gttagatata aattcttttt taaatggatt
     2221 ttttaatata atattaagaa tgagtatata tgatttaatt gacatatcta tagtagcgta
     2281 tattttttac aaaatattta tgtttataaa agatacaaga gcagaacaag tgtttaaagg
     2341 tataatattt cttttattag caactcaact tagtaacacc tttaaattgc ataccgttta
     2401 ttggatatct cttaaagctt tagattatgg agttatagct gctcttataa tttttcaacc
     2461 agaatttaga gcaggacttg aacatatagg aagagcaaag tttaatttat ttggaaagaa
     2521 tgtaaatact tctgaagaaa ctctcaatag aaatatagaa gaaattgtag aagctttata
     2581 ttcactttct agacaaaaaa taggagctct tatcataatg gagagagaaa ctagaataag
     2641 tgatataata aatacaggaa ctattattga tgctgaaatt tctaggcaac tattaataaa
     2701 tatatttata ccaaatacac cattacacga tggagctgtt gtaattagag attctaaggt
     2761 aaaagcagct gcatgttttt tgccattgac agaaagtaag gatttaagta aagatttggg
     2821 cactagacat agagcaggaa taggggtaag tgaggtgtct gactgtataa ctttgattgt
     2881 atcagaggaa acaggtggcg tatcaattgc taaagcaggt aagttatata gagatatttc
     2941 tagagaaaga atgatgaata tattacgtag taatttaaaa acaaatacag aaacaagaag
     3001 ttttttcaaa ggtggtatat ttaaatgata aatagactaa aaaataatac caaaataaaa
     3061 ataatatcat ttttaagtgc aattgcatta tggatgtatg ttatggctgt agttgaccct
     3121 gaagaaacta aagggtttga agatatacct gtatctataa gtaatatgag tgatttaaag
     3181 gataaaaatc ttgttatata tccagacgaa aaattaacag cagatgtata tataaaaggt
     3241 agtttatcaa aggtacaaag tgttaaaaaa gaagatatac atgtatatgg aaccattgaa
     3301 gacccaatac aaggacagaa ggaagtatat ttaaaagcaa atattcctca aggtgttact
     3361 ctagaattta agcatgatgt tttagtagta aatcttgaaa aaaacataaa agaaaaaaga
     3421 gatataaagg tagaagtaag tggaaattca aaaagaaata taaataaaat tgaacttagt
     3481 aaggaatttg tcgatgtatc aggtccaaga actctagtta aagaagtcaa aagtgtaaga
     3541 gctaatctag atgttggtaa tgagacagat gatttttcta aaaaattgca attaatacca
     3601 ttaaatagtg atggaactaa ggttgaagga gtaacattaa gttcatcctt tgtgactgca
     3661 aagatagagc tattaaagga aaaaattgtc ccaataagag taagtctaaa tgataataaa
     3721 gataatgatg tactgaaaaa ctataaatta agtaaggaac aagttacaat aaaaggaaag
     3781 aaagaagata tagacaaaat aagttatatt aagacaaaac ctattgactt agctgatttg
     3841 gctaatggtg aagaaaaaga agttagctta gaaattccag agggtataac tcttgaggat
     3901 agctctataa caattaaatt aaatgataca aaacaattga gtgcagaatt tttatataat
     3961 gcgggagata ttgaattaag aaatatccca acaaatatgg ataatccaaa tgtaatttct
     4021 gatgtagata taaaagttgt tgtagagtca acggaggatt tgagtaagtt aaataaaaaa
     4081 gatatttcat tatatattga tttatcacaa ggtcctgagg aagatagtaa atataaaata
     4141 aaatatgaaa caacatatca atttaaaaaa ataaatatag aacctaatat tgttgaagtg
     4201 gaatgaacaa atatttcgaa tatttagttg ttacaagatg cgacaaaaaa acctataaaa
     4261 ttaagtttgt taattttatg tttttgttgc atcttgttta ttttagttat attataaaat
     4321 aaggacaatg agatatttgt taaatctaaa aagcgctaga tatatgaaaa aagactgata
     4381 aatagattta aataaatatt ttgaattaaa tatttcaatt atctctagga aaacgttgct
     4441 gaacgagtta taatttaatt gagatataaa aagttctatt tcaaaaaatt caagatgagg
     4501 tggaaatgca tgagaagttt tgaagaagta attaagtttg caaaagaaag aggacctaaa
     4561 actatatcag tagcatgttg ccaagataaa gaagttttaa tggcagttga aatggctaga
     4621 aaagaaaaaa tagcaaatgc cattttagta ggagatatag aaaagactaa agaaattgca
     4681 aaaagcatag acatggatat cgaaaattat gaactgatag atataaaaga tttagcagaa
     4741 gcatctctaa aatctgttga attagtttca caaggaaaag ccgacatggt aatgaaaggc
     4801 ttagtagaca catcaataat actaaaagca gttttaaata aagaagtagg tcttagaact
     4861 ggaaatgtat taagtcacgt agcagtattt gatgtagagg gatatgatag attatttttc
     4921 gtaactgacg cagctatgaa cttagctcct gatacaaata ctaaaaagca aatcatagaa
     4981 aatgcttgca cagtagcaca ttcattagat ataagtgaac caaaagttgc tgcaatatgc
     5041 gcaaaagaaa aagtaaatcc aaaaatgaaa gatacagttg aagctaaaga actagaagaa
     5101 atgtatgaaa gaggagaaat caaaggttgt atggttggtg gaccttttgc aattgataat
     5161 gcagtatctt tagaagcagc taaacataaa ggtataaatc atcctgtagc aggaagagct
     5221 gatatattat tagccccaga tattgaaggt ggtaacatat tatataaagc tttggtattc
     5281 ttctcaaaat caaaaaatgc aggagttata gttggggcta aagcaccaat aatattaact
     5341 tctagagcag acagtgaaga aactaaacta aactcaatag ctttaggcgt tttaatggca
     5401 gcaaaggcat aattttaagg gggaaatagg caaatgagca aaatatttaa aatcttaaca
     5461 ataaatcctg gttcgacatc aactaaaata gctgtatttg ataatgagga tttagtattt
     5521 gaaaaaactt taagacattc ttcagaagaa ataggaaaat atgagaaggt gtctgaccaa
     5581 tttgaatttc gtaaacaagt aatagaagaa gctctaaaag aaggtggagt aaaaacatct
     5641 gaattagatg ctgtagtagg tagaggagga cttcttaaac ctataaaagg tggtacttat
     5701 tcagtaagtg ctgctatgat tgaagattta aaagtgggag ttttaggaga acacgcttca
     5761 aacctaggtg gaataatagc aaaacaaata ggtgaagaag taaatgttcc ttcatacata
     5821 gtagaccctg ttgttgtaga tgaattagaa gatgttgcta gaatttctgg tatgcctgaa
     5881 ataagtagag caagtgtagt acatgcttta aatcaaaagg caatagcaag aagatatgct
     5941 agagaaataa acaagaaata tgaagatata aatcttatag ttgcacacat gggtggagga
     6001 gtttctgttg gagctcataa aaatggtaaa atagtagatg ttgcaaacgc attagatgga
     6061 gaaggacctt tctctccaga aagaagtggt ggactaccag taggtgcatt agtaaaaatg
     6121 tgctttagtg gaaaatatac tcaagatgaa attaaaaaga aaataaaagg taatggcgga
     6181 ttagttgcat acttaaacac taatgatgct agagaagttg aagaaagaat tgaagctggt
     6241 gatgaaaaag ctaaattagt atatgaagct atggcatatc aaatctctaa agaaatagga
     6301 gctagtgctg cagttcttaa gggagatgta aaagcaatat tattaactgg tggaatcgca
     6361 tattcaaaaa tgtttacaga aatgattgca gatagagtta aatttatagc agatgtaaaa
     6421 gtttatccag gtgaagatga aatgattgca ttagctcaag gtggacttag agttttaact
     6481 ggtgaagaag aggctcaagt ttatgataac taatgataaa agaataagaa tcataactgg
     6541 tcactatgga agtggtaaaa gtgaatttgc gatgaactat gttgttaagt taagagatat
     6601 ggtttctggc aaagttgcta tagccgattt agatgtggta aatgtatact ttagaactag
     6661 agaaaagaaa gagttaatga aatccttagg tatacaacca atagatagct caattaatgc
     6721 tccaacatta gatttaccag cagtatcagc agaggtaatg tctcctatgg tagaccattc
     6781 atacaattct gttatagatt taggtggaga taatgtaggt gctagggtta taggaagatt
     6841 tagtcatttg ttaaaagaag gcgattatga tatgcttttt gtaataaatg caaataggga
     6901 gaaaactcaa acttctgaag aagttatcca atatataaaa gaaatagaaa aatcttctaa
     6961 attaaaggta acaggtctaa ttaataatac tcatcttatt aggtttacta ctattgatga
     7021 tgttttaaga ggtcagaaag ttgcaaaaga agtttctgaa aaatgtaata taccgataag
     7081 atatgttgca tgtttagaaa atcttgttga acagttacca aaagatttag aaggagaaat
     7141 ttttcctata aaattatata tgagagaaga ctggatgtag tttgagctca aatatataga
     7201 aagtttaagg aggcttaggt aaatggctaa aggaaaagta tcttttaatc aagaacgttg
     7261 taaaggttgt ggattgtgtg ttgaagcatg tccagtaaaa atcatacaat tagactcaaa
     7321 tgtaataaac aaaaaagggt ataacccagc aactgttttt gaaatggaaa aatgcatagg
     7381 atgtgcaagt tgtgcaacta tgtgtccaga tgtagttata acagtagaaa gagattaatt
     7441 taattaatat ttaaggggga attttaatgg ctaagatact tatgaaaggt aacgaagcat
     7501 ttggaaaagc agctatagaa gctggttgca aatatttctt cggttaccca ataactccac
     7561 aaagtgaatt accagaatat ttatcaagag agttacctaa aataggtgga gcgttcgttc
     7621 aagctgaatc agaagtttct gcgataaaca tggtttatgg tggagcaggt gcaggagcaa
     7681 gagttatgac ttcttcatct tcaccaggag ttgctttaaa gcaagaaggt ataacatatg
     7741 cagtaggagc agaagttcct tgtgttgtac ttaatgtaat gagaggtggt ccaggacttg
     7801 gaagtataca accttcacaa gctgactact ttatgtctac aagaggtgga ggaaatggag
     7861 actacagaac tccagtattc gcaccagcta cagttcaaga agctgttgat atgataatgg
     7921 aagcttttga cgttgcagat tattacagat caccagttat ggtagttgca gatggtatga
     7981 taggtcaaat gatggagcca gttgaattta gagctcctga gaagaaaaga gaattgcctc
     8041 ctaaagattg ggcaactgtt ggaactaaag gaaaaagaaa acctaatgta ataaactctc
     8101 tatacttaga gccagaagta ctagaagacc attgttggca tttacaagaa aaatttgatg
     8161 caatggaaaa gaatgaagta caatacgaaa tgtacaaaac agaagatgct gaatttgtat
     8221 ttgcagctta tggaactact tcaagagtag taaaaagcgc aattgatata ttaagagaag
     8281 aaggaataaa agcaggtctt ataagaccta aagtattatg gccattccca ttcgaagcat
     8341 tcaaccaaat tcctaatgct agaaacatat tgactgttga aatgagtatg ggacaaatgg
     8401 tggaagatgt taaaatggca gtagaaggta aattaccagt ttacttccat ggaagaccag
     8461 gaggaatgac tccaacacca gcagaaatag ttgaaaaagc taaaaaaatt attgccggag
     8521 aattggttgc aggaggtgct agataatggc tgttgtattt aagaaaactg aaggattaca
     8581 agatactcaa actcactact gtccaggatg tacacatggt ataatccata gattagttgg
     8641 tgaagtatta gaagaactag gagtattagg tgatgctgta ggtgttgttc cagttggatg
     8701 ttcagtttta ggatataaat attttaactg tgacactcaa gaagctgctc atggtagagc
     8761 gccagctgct gctacaggaa taaaaagagt tcatcctgaa aatacagtat tcacttatca
     8821 aggtgatgga gacttagctt caattggtac tgctgaaata gttcatgcag ctgctagagg
     8881 agaaaaaata actactatat ttgtaaacaa tacaacttat ggtatgactg gtggacaaat
     8941 ggctccaact acattagttg gacaaagagc tactactgct caatcaggaa gaaatgctga
     9001 aactcaaggt tatccaataa gagtaagtga aatgttagct acattaacag gagctgtatt
     9061 tgtagaaaga gtagcagttg atactccagc tcatgttaga caagctaaaa aagctataaa
     9121 gaaagcattc caagttcaac aagcaggatt aggatttgga atagtagaag tattatctac
     9181 ttgtcctaca aactggggac tagctccaaa cgatgcttta caatggttaa gagacaacat
     9241 gataccatac tatccattag gaaatttcaa aaatgttgaa gttgaggagg tgaagtaaat
     9301 gtctacagct agagtaatat gtgcaggctt cggaggccaa ggtgttatgt ctatgggaca
     9361 attacttact tatgcaggaa tgctagaagg aaaagaagtt tcttggttac catcttatgg
     9421 accagaaatg cgtggaggta cagcaaactg tgcagtaact gtatctaatg agccagttgg
     9481 ttctccactt ataacagatg atgcaactgc agctatatta ttaaatatac cagcatttga
     9541 aaaattcaaa gatgatgtta ttcctggtgg aaaaataata gtaaatagtt ctttaataaa
     9601 agaaaaagtt gatagaacag atgtagatgt ttattatata ccagcaaatg aattagcagc
     9661 tgaattagga aatgataaag ttgctaacat gataatgtta ggtgcttact taaaagtatc
     9721 tgatactgta gatatagaat ctgtactaga agcattcaaa aaagttttcg gacctagaaa
     9781 agaaaaattc gttccattaa acagagaagc tttacaaaaa ggtatggatg ctacatgttc
     9841 taaagcaact aactaataaa gaaaaagatg tcaaaaaaaa gacaatagaa ttatttctat
     9901 tgtctttttt gctgataagt attaaaatat ttttatgact gaaattaagc ctataatgat
     9961 attttatgaa ctataaaaat ataatacaaa ttacaagctt ttcaattatg aaaggagaat
    10021 ctttagtgag aaagtatttt ggaacagatg gagttagagg agtagcaaat acagaactaa
    10081 catgtgattt agcatataaa cttggtagag ctggtggatt tgtcttagct caaggagacc
    10141 acagagtaaa agtagtagta ggtaaggata ctagaatatc aggtgatatg ttggaagcat
    10201 ctttaatagc aggacttatg tctgttggat gtgatgttat tactgttgga ataataccaa
    10261 cacctgcagt ggcatattta actagaaaat atggtgctga ttgtggtgtg gttatatctg
    10321 catctcacaa tcctgttgaa tataatggaa tcaaattctt taataagaat ggatataaat
    10381 tagatgatga aattgaattg aaaatagaag aatatataga cgatatagac aaaattgatt
    10441 gtcttccaat tggtgaaaat gtaggaagaa aattacatga acattgtgca caaagagact
    10501 atgtagacta cctaaaatca ataataagca ctgactttaa gggattaaaa gtagttttgg
    10561 actgtgctaa tggtgcgtca tataaagtgg caccaatagt gtttgatgaa ctaggagcaa
    10621 gtgtaatttc aataaatagt tcaccagatg gaaataatat aaactataaa tgtggctcta
    10681 cacatccaga acaacttcaa agggctgttt tggaacataa tgctgactta ggtcttgcat
    10741 atgatggaga tgctgataga ttaattgcag taaatgaaaa gggtcaaatt gttgatggag
    10801 accatataat gatattgagt gccttaaatt taaagaaaaa taataaattg gcacaagata
    10861 ctttggtagt tacagttatg agtaatatag ggttgacaat agctgctaag gaaaatggaa
    10921 taaatttatc tactacagca gttggagaca gatatgtttt agaagatatg gttaaaaatg
    10981 gatataatct tggtggagag caatctggac atatgatatt tttagattac aacactactg
    11041 gagatggagt gcttagttct ctaatacttg caaatataat cttgcaagaa aagaaacctt
    11101 tatcagaaat tgcatcaata atgagccaat acccacaagt attagtaaat gcaacaataa
    11161 aaaatgaaaa taagaacaaa tatatggaat atccagaaat aaaaactgag atagaaagaa
    11221 tagaatctat tttagacgga aatggtagag ttttgataag accatcagga actgagccat
    11281 tagttagagt tatgttagag ggtaaagagg aaggtcaaat aaaagaatta gcaacaaact
    11341 tagctaatct tatacaagaa aaattatcgt aatttaaagg gtattctcag atataaatac
    11401 tgaggacacc tttctaagcg ccagaactta gttatagaca taattattga gtaatatagg
    11461 aactaagttg acgaggtcag agttaatcga attgtcggcg gatgctctgc ggtgtgttta
    11521 ccatcgaaag acttctttaa ataataggag caatcctatg gacaaaggga agccaaagta
    11581 aacttatatg acctaactct taaaatatat aaataatatt tttaggagga cacaaataat
    11641 gtgtggaata gttggatatt taggaagtag aaaggcagca gaagttatag tagaagggct
    11701 ttctaagcta gagtacagag gttatgactc agcaggagta gcagttaata gttctaatga
    11761 aaaagaactt aatattagaa agtttaaagg tagactttct gtacttgcag aagacttaga
    11821 aaagaatcct attgatggaa atttaggtat agggcatacg agatgggcaa ctcatggaga
    11881 accatctgat gtaaactcac atcctcattt taatcaagcc aaaacaatag cagttgttca
    11941 taatgggata atagaaaact atatggaaat aaaagaagaa ttaatttctg aaggtgttaa
    12001 gtttgaatct caaacagata cagaggtaat agcacattta gtagataaat actatgaggg
    12061 taatttatta gatgctgtat acaaaactat atcaaaatta agaggagctt atgcattagg
    12121 tgttatatgt aaagaacatg gaaatgaatt agttgcagta agaaaagata gtcctcttgt
    12181 agttggtgtt ggtgaaggtg aaaactttat agcatcagat atacctgcat tattaaaata
    12241 tactagagat gtttatttct tagaaaatgg agaagtagtt catctaaaag acgaaaatgt
    12301 aacagtttat gactctaata gaaatcttgt tgaaaaagaa gtatttcatg taacttggga
    12361 tgtagaagct gcgtctaaag gtggatatga ctactttatg tcaaaagaaa ttcatgagca
    12421 accaacagga gtaagagaaa ctttagaaag aagacttgat gataatggaa atataattct
    12481 agacagtata aatatttcta aagaagactt agaaaaaata aataaagttt atatagtggc
    12541 ttgtggaaca gcatataatg ctggattact tggtaagtat gccatagaaa aatttgtaaa
    12601 tataccagta ataactgata tagcatcaga atttagatat agcgacccat ttgtagatga
    12661 aaattcatta gtaatattag ttagtcaatc tggtgagaca gcagatactc tagcagtatt
    12721 aagagattca aaggctaaag gagcaagaat actttcaata actaacgttg taggttcatc
    12781 tatagcaaga gaatcagatg atgtattcta tacttgggca ggacctgaag tagcagttgc
    12841 atcaactaag gcatatacta ctcaaataac ttctttatac atgatagctt tagactttgc
    12901 tatcaaaaaa ggaacaataa ctagagaatt ttatgatagt atgatttcta agatgaaaga
    12961 aataccatca aaaatacaag aaatactaga caatgaagaa tatataaaag aagttgctaa
    13021 aacagttgtt agttctgaac atgcattcta tttaggaaga ggtatagact atagcttagc
    13081 aatggaaggt tcattgaaat taaaagagat ttcatatata catgcagaag cttttgc
//
LOCUS       DAJMZY010000115        12989 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.116, whole genome shotgun sequence.
ACCESSION   DAJMZY010000115 DAJMZY010000000
VERSION     DAJMZY010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12989)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12989)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12989
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.116"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            65..946
                     /locus_tag="OE968_003176"
     CDS             65..946
                     /locus_tag="OE968_003176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCP7220422.1"
                     /translation="MNLYHLRYFVTLAHLEHYTKAAENLSITQPSLSHAISLLENELG
                     VALFEKEGRNIVLTKYGKIFLKDVEKSLEILDSSVKSLKITGTGEGQIDLAFLRTLGT
                     DFIPDIVHKFLKSNPAKSIDFKFHTGVTTDIIQGLKERKYDIAFCSKLEKEKGIEFIP
                     VAKQDLVLIVPYSHPLAAKDTIDLKETIPYPQIVFNQRSGLRYIIDDMFKKINQQPNI
                     VYEVEEDQVIAGLVAKNFGIAVVPNMNMLSFTKVKVIQIIHPSWERNFYLAFIKDRYL
                     PPAIKNFKNFVIKNAQL"
     gene            complement(1154..2017)
                     /locus_tag="OE968_003177"
     CDS             complement(1154..2017)
                     /locus_tag="OE968_003177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3800 domain-containing protein"
                     /protein_id="HCP7220423.1"
                     /translation="MLSSYVKRVSKIIKKKYIMFIDESGRADINHEDPFTLTGVIFEY
                     KYAVSQGDYVCSLRKEMDAFKEYCFGTSNIGIHLTDISRKSRAFEKFDDSQIKLFYDE
                     LPLFLSRLECTIISVTVDKARLKKYYAPSKEPYVVAFIHVLQNFYSFVNNETVESARI
                     VIESRDDVSNLKVQKAFFDVFNNGTIYLDIDEELRDKVKGFIIAKKEDADYREGLEIA
                     DILCNPLSRARRGLIEANPKCMQYGEKNKIFKSVRNKIYTPTSVNDIRNWGFKEVPIV
                     EPVGPWLEKMR"
     gene            complement(2172..4106)
                     /locus_tag="OE968_003178"
     CDS             complement(2172..4106)
                     /locus_tag="OE968_003178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp22"
                     /protein_id="HCP7220424.1"
                     /translation="MKKSLKKYLVLALTLVLVFACGVPESSAASKHVIIVNSRKNTLG
                     YFVNNKLVKEFRVATGKKGSETPTGKTKVVNKIKNRPYYKGNIPGGSPRNPLGDRWMG
                     LALKGTYGDTYGIHGNNNESSIGKHISGGCIRMHNKDVRWLFDQVPVGSDVIIDYSND
                     SYVKIAAKYKINLNQTGWKTENGKKYYVKSDGTYQKNSWLKVNGKMYYFDASGVMQTG
                     WKTINNKKYYLGTDGARVSGWKVIDGKTYYFNSDGVMQTGWQEKNGKKYYLGSDGLAV
                     TGWQEIDGNKYYFDKTGIMQTGWQQIDGKSYYLDKDGKMLTGSQKIDGKDYTFNEDGT
                     INPTWDTIIGANRFDTAKKISSVGNWNADSSDTVILVNGNAIADGITATPLASSYDST
                     ILLTNTANLPTETVEEMKLLAPKTVILIGGENAISSKLEQEIKTTFNTETKRIAGQDR
                     YQTATRIAEELGNREEIKTAYMVSGNGEADALSVASKAGEEKQPIILVNKDGITEESY
                     KWLTERKLENAYFIGGPSAINDSVIAKMNDITTEDISGNRIYGDSRVDTNAKVIEKFY
                     GDTDLQAVLVSKSDALVDALSAGPLAVKLHSPIVLMDNSGLSSEQQRVFANKKVETPY
                     QIGGGVSYIVMDKLMDILAK"
     gene            complement(4218..5231)
                     /gene="galE"
                     /locus_tag="OE968_003179"
     CDS             complement(4218..5231)
                     /gene="galE"
                     /locus_tag="OE968_003179"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HCP7220425.1"
                     /translation="MAVLVAGGAGYIGSHTAIELLESGYEVVIVDNLSNSNSIVVDRI
                     KELSKKPVKFYNIDIRNKDEMHVVFKENNIESIIHFAALKAVGESVEKPIEYYSNNLI
                     STLNLFELMREYGVKKFVFSSSATVYGDPHTCPILEDFPLSVTNPYGRTKLMIEQMLV
                     DISKADKSLDIALLRYFNPVGAHKSGRIGEEPNGVPSNLMPYITKIAVGKLKELSVYG
                     NDYPTHDGTGVRDYIHVLDLAAGHVKALQKLEENPGLVVYNLGTGKGYSVLDLVKAFS
                     KASGKEIPYKIVGRRAGDVAMCYADSSKAEKELGWKAKYELEEMCEDSWRWQSMNPNG
                     YEE"
     gene            complement(5255..6124)
                     /gene="galU"
                     /locus_tag="OE968_003180"
     CDS             complement(5255..6124)
                     /gene="galU"
                     /locus_tag="OE968_003180"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HCP7220426.1"
                     /translation="MTVKKAIIPAAGLGTRFLPATKSQPKEMLPIVDKPTLQYIIEEA
                     IESGIEEILIITGRNKKSIEDHFDKSVELELELEQKGKTEMLEMVRDISNMVNIHYIR
                     QKEPKGLGHAIYCAKSFIGDEPFAVLLGDDIVDSDVPCLKQLIDTYNEYKTTVLGVQK
                     IAKEDTNKYGILDVKHIEDRVYKVKDMVEKPAIEEAPSDIAILGRYIITPAIFSILEK
                     QTPGKGGEIQLTDALQTLGKQEAIYAYNFEGRRYDVGDKIGFLEATIDFALKRENLKD
                     DLMDYMRKKVSEK"
     gene            complement(6322..6642)
                     /locus_tag="OE968_003181"
     CDS             complement(6322..6642)
                     /locus_tag="OE968_003181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220427.1"
                     /translation="MSSKYNVWTFNYEFLGLDSGDEKNNEVYYEIDLDEILNENYIDE
                     DIDSGLDSDGNSILGELISEMDIDEDVSVDMTYQELEVDLEDLDSYLDEDIDSDIKGI
                     LDEI"
     gene            complement(6632..8623)
                     /locus_tag="OE968_003182"
     CDS             complement(6632..8623)
                     /locus_tag="OE968_003182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220428.1"
                     /translation="MLKLGEKIIYELSDGFELSGISRYSKEYKKLHITNLGNIIISKS
                     DEVNEDTGVKYIYSFSDNKEKLEAVLEDSQIIVYGNNLPFYIKSENSSKNVTANLTMK
                     ITLDEYDLICKSQREFIFYLKDNMTILSLDDNKFYMGGINKDNEKFIFISGKNRFEIN
                     FDDIERYILEDKRVSLKGYFHMEREGIIVRSVSIFNNNIDSVVPSDLNERVKDNQKIG
                     NLPKDCEIVFCKISGNIDGFDYKNTNMLLVKYQDQLIFINKKSKKTIVKSAKDNCSKL
                     NLGEDIILYDNKNVFNLHINDKNREIMQIDDLKDIENEIVGYTLKHAPFFIQEDFDSL
                     TILKSFQKEIISIKNSDIKDIVINKELENENSNFVETEIKFNNQKVLLNLSKSMVQKL
                     MQDVFIYAKQPLLKENSIEVIYKNWSKAMNDMIIFNFFGNIYYMKSEFDKILEKELND
                     EIRIEVINSLYKQIQEQRNNLDLLSAYMPRILENQEIDLFEKYNTKLDVQVFKQIKNL
                     LSDLSYNISSYLNEVEKSLDNIIFVISGEDKKKYNYRMLKESESASLDVFLKQAISRL
                     NHLVENMYPYYVDETSREMFKLFELLWKNYRNIDDDSIKEILFERITNTYVFKQLTLN
                     NSTKERRKDIIEKIYNSVDYGTNKLDENMFFTGGIKYVK"
     gene            complement(8746..11289)
                     /locus_tag="OE968_003183"
     CDS             complement(8746..11289)
                     /locus_tag="OE968_003183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPOR domain-containing protein"
                     /protein_id="HCP7220429.1"
                     /translation="MKVLSENNIIRNTVLNVTASFLKQESKINEKLDGVLEKKFEKVE
                     FNEAKYAELLKFNILFYKTLARNTEPLIGKWIVDKYIPEIDELEKDLELTTAKCRKYV
                     NKAMKEGLDSLKANDLNSFLAYDKMELSERRRRLEKDYKVLNLYKDLLNISLRKISLE
                     KKECGDLFLKNQADAKRELKREIIFCVNKILASNKDVVPNNVEENNEQNKVEIKATEI
                     EDLQLGKDNSENDMLLNEIKNSKVKHESKSNDIESKFIDKLNSLNNESISQTIHNEYK
                     KLCGLEELHSVEAYGFGKEIIKDFACATVVLEFLKRRNRDLIEGAMRLTIIGEFGPEN
                     FKEFVDYVIKNKTEISEDTWNKAQNLIKDNYSELENHEIASKRTRRNKDIDIEEYIYM
                     IKNADKDICFRSSISIEDDAEEGTKEEVDSNNQDIGDVVEDKDTTDKEYDSNKEDIIE
                     PENKKSKKKAKLFGFIKKDNEEAEQEEENLNDISPDIILDKPVENHQVKSEEIEQNEL
                     KEIKQEEPSQHIEEERSVKIEKPINNNLDEKVSSNNESKLEKESKNLEDKKAKEIKEE
                     KLENEKSVVIPIKKKENSNKKSKNSSKDKYRENKKEMKNYVSDKEDSLDDEEVVSKKS
                     RLKETIIAVVIVVIVGVGYFITVGNNKKNDKENIPKSSTQQQANNKLTEEEKKAQAEK
                     EKKEAEEKAKAEKEAQEKAQAEKKAKEMEAYKDGKGVYYTVYAGSLKVEKTAKETAKE
                     YEAKGISSTIIQENGYYKIKIGDYSQYGEAQEKCNELAKKSIDTYIAMYDKYYDYKLE
                     ELKESAPSLSAEELKQKYEDLRSELKNKSGYREYVKHLDKLYEEIVEGA"
     gene            complement(11567..11901)
                     /gene="rnpB"
                     /locus_tag="OE968_003184"
     ncRNA           complement(11567..11901)
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="OE968_003184"
                     /product="RNase P RNA component class A"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00010"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00010"
     gene            12033..12710
                     /gene="srtB"
                     /locus_tag="OE968_003185"
     CDS             12033..12710
                     /gene="srtB"
                     /locus_tag="OE968_003185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtB"
                     /protein_id="HCP7220430.1"
                     /translation="MKKLYRIVINIILVLVILYSGFNIYSKLTKYNHDTKISSELQKK
                     EYKKEDLSKINSDFKFWLSVENTNINYPVVQSKDNSYYLDKDFYKKDSISGTLFMDYR
                     NKSIDDKNIIIYGHNMKNKTMFNNLNKFKDADFFKKNNKIKITLNGKEFLYDVFSAYI
                     VESDYDYLKTNFNNESDYQNYINDITSKSLYKSPIKVNSNDKIVTLSTCTYEFDDARM
                     VIHGRLI"
     gene            complement(12870..12944)
                     /locus_tag="OE968_003186"
     tRNA            complement(12870..12944)
                     /locus_tag="OE968_003186"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(12910..12912),aa:Thr,seq:tgt)
BASE COUNT         3990 a         2285 c         1329 g         5385 t
ORIGIN      
        1 atatcttaaa ggttaacttc tacaaatata taaataaaaa tacctatgaa aggatgaaca
       61 aaaattgaat ttatatcact tacgctattt tgttacattg gcacatttag aacactatac
      121 aaaagcggca gaaaatttat ctataacaca accaagctta agtcatgcta tttctttact
      181 agaaaatgaa cttggggtgg ctctatttga aaaagaaggt agaaatatag tccttactaa
      241 gtatggaaaa atatttttaa aagatgtgga aaaatcatta gaaattttag attcaagtgt
      301 aaaatcatta aaaataactg gtactggtga aggacaaata gacttagctt ttcttagaac
      361 acttggtact gattttatcc cagacatagt gcacaaattt ttaaaatcta atcctgctaa
      421 atcaatagat tttaaatttc atactggtgt aactactgac attattcaag gtcttaaaga
      481 aagaaaatat gatattgcat tttgttcgaa acttgaaaaa gaaaagggaa ttgaatttat
      541 acctgttgcc aaacaagatt tagtactaat tgtaccatat agtcatccac tagctgcaaa
      601 ggatactata gatttaaaag aaaccatacc ttatcctcaa atagtattta atcagagaag
      661 tggtcttaga tatataattg atgatatgtt taaaaaaata aatcaacagc ctaatatagt
      721 ctatgaagta gaggaagacc aagtaattgc tggattagtt gcaaaaaatt tcggaattgc
      781 tgtagtccca aatatgaata tgcttagctt tacaaaagta aaagtaattc agattattca
      841 cccaagttgg gaaagaaact tttacttagc atttataaaa gatagatatt tgcctcctgc
      901 aattaaaaac tttaaaaact ttgtcattaa aaacgctcaa ttataattta ttaataaagg
      961 ggttattttt aaatatcctc ttttattctt tttataaaat aaaaaaatct atacttttaa
     1021 aagtatagat tcctaactga cagtcggcat ccgagtctca gtaattatcg ttatacaaca
     1081 gcaactggat tcagttcctg aataactagg ttacttacat tatatcagat tttttaaaat
     1141 ttgtcaattg tatctaacgc attttttcaa gccatggtcc aacaggctct acaataggaa
     1201 cttctttaaa tccccaattt cttatatcat tcacactcgt tggagtatat attttgtttc
     1261 tgacagattt gaatattttg tttttttctc catattgcat acactttgga ttagcttcta
     1321 ttaaccctct tcttgctctg ctaagaggat tacataaaat atctgctatt tctaaacctt
     1381 ctctatagtc agcatcttct tttttggcaa ttataaaacc cttaacctta tctcttaatt
     1441 cttcatctat atctaagtat attgttccat tattaaatac atcaaaaaac gccttttgta
     1501 cttttaagtt tgagacatca tcccttgact ctataactat tcgtgcagat tctacagttt
     1561 cattatttac aaatgaataa aaattctgaa gaacatgtat aaaagccaca acatacggtt
     1621 cctttgaagg tgcataatat ttctttaatc tagctttatc tactgttact gatattatag
     1681 tacactctaa tctagataga aataaaggca actcatcata gaataactta atctgtgaat
     1741 catcaaactt ctcaaatgct cttgattttc ttgatatatc tgtcaaatgt attcctatgt
     1801 tactggttcc aaaacaatac tctttaaatg catccatttc tttcctcaaa gaacatacat
     1861 aatcgccttg acttactgca tatttatatt caaaaattac tcctgtcaat gtaaatgggt
     1921 cttcatgatt tatatcagct cttccacttt catcaataaa cattatatat tttttcttta
     1981 taatcttact caccctctta acatatgatg atagcatcta tattcatttt atatgagttt
     2041 taaaaatatt ccaagatttt tatataactt aaacttaatt ttatactaaa aaattgagat
     2101 gtaaaacaat caagctttta ttgattgaat ttcacatctc aattataatt atttttcaat
     2161 atatattttt actattttgc aagaatatcc attaatttat ccattactat ataagatact
     2221 ccgcctccta tttgataagg agtttcaact tttttatttg caaatactct ttgttgctct
     2281 gatgataatc ctgaattatc cattaaaact attggtgaat gtaattttac agctaatggt
     2341 ccagctgata aagcatctac taaagcatct gatttactaa ctaatacagc ctgtaaatca
     2401 gtatctccat agaatttttc tatcactttg gcattagtat ctactctact atctccatat
     2461 attctatttc ctgaaatatc ttcagtagtt atatcattca tttttgctat tactgaatcg
     2521 ttaattgcac ttggtccacc tataaagtat gcattttcta attttctttc tgttagccat
     2581 ttataagatt cttctgtaat tccatcttta ttgactaata ttataggttg tttttcttcc
     2641 ccagctttag aagctacaga taaagcatct gcctccccat ttccagaaac catatatgca
     2701 gtttttattt cttctcgatt tccaagttct tcagctattc ttgtagcagt ttgatatcta
     2761 tcttgacctg ctattctctt tgtttctgtg ttgaaagtag tttttatttc ttgctctaat
     2821 ttagaactta ttgcattttc tccacctatc aagattactg ttttaggtgc taataacttc
     2881 atttcttcaa cagtttcagt tggtaaatta gctgtattag taagtagtat tgttgagtca
     2941 tagctacttg ctaaaggagt tgctgttata ccatcagcta ttgcattacc atttactaat
     3001 attacagtat ctgaactatc agcattccag tttccaactg aacttatctt tttagctgta
     3061 tcaaatctat ttgcacctat aattgtatcc catgtaggat ttatagttcc atcttcatta
     3121 aaagtataat ctttcccatc tattttttga gaaccagtta gcatctttcc atctttgtct
     3181 aaatagtaag acttaccatc tatttgttgc catcctgtct gcattattcc tgttttgtca
     3241 aagtaatact tattaccatc tatttcttgc catcctgtta ctgctaaacc atcagatcct
     3301 agatagtatt tctttccatt cttttcttgc catcctgttt gcattactcc atctgagtta
     3361 aagtaataag tttttccgtc tattactttc catccagata ctcttgctcc atcagttcct
     3421 aaataatatt ttttgttatt aattgttttc catcctgttt gcattactcc tgaagcatca
     3481 aagtaataca tttttccatt tacttttagc caactattct tttggtatgt tccatcagat
     3541 tttacataat acttcttacc attttctgtt ttccatcctg tttgatttag atttatctta
     3601 tattttgccg ctatctttac atagctgtcg ttactataat ctataattac atctgaacct
     3661 acaggaactt ggtcaaataa ccatctaaca tctttattgt gcattcttat acatccacca
     3721 gaaatatgct ttcctataga actctcatta ttatttccat gtattccata tgtatctcca
     3781 taagttcctt ttaatgctaa tcccatccat ctatctccta atggatttct tggacttcct
     3841 ccaggtatat tacctttata atatggtcta ttttttatct tgttaactac ttttgttttc
     3901 cctgttggtg tttctgaccc ctttttacct gttgcaactc taaattcttt tacaagttta
     3961 ttatttacaa aatatcctag agtatttttt cttgaattta ctataatcac atgtttactg
     4021 gctgcgcttg attctggtac gccacatgca aatactaaaa ctaaagtcag tgctagtact
     4081 aaatactttt ttagactttt tttcactata acttccccct cttttagaaa cattactaca
     4141 tgtgtctaat tataacataa aattaccaat accttatatt tacaaatttg ttacatttat
     4201 acatataagt atgtattcta ctcttcatac ccattaggat tcatactttg ccatctccat
     4261 gaatcttcac acatctcttc aagttcatac ttagctttcc atccaagctc tttttctgcc
     4321 tttgaagaat ctgcataaca catggctaca tctccagccc ttcttcctac aatcttatat
     4381 ggtatttctt ttccacttgc tttagaaaat gcttttacta aatcaagaac actatacccc
     4441 tttccagttc ctaaattata aacaacaagt cctggatttt cttctaattt ttgtaatgct
     4501 tttacatgac cagcagctaa atctaataca tgtatatagt ctctaactcc agttccatca
     4561 tgtgttggat agtcattacc ataaacactc aattccttca atttacctac tgctattttt
     4621 gttatataag gcattagatt gctcggaact ccatttggtt cttcacctat tctaccactt
     4681 ttatgagcac cgactggatt aaagtatctt aaaagagcta tatccaatga cttatctgct
     4741 tttgatatat ctactaacat ctgctctatc ataagtttag ttcttccata tggattggtt
     4801 acagaaagtg gaaaatcctc taatatagga caagtatgtg ggtctccata tacagtagct
     4861 gaagaactaa atacaaactt tttaacacca tattctctca ttaattcaaa taaatttaag
     4921 gtacttatta gattattgct gtaatattca attggttttt ctactgattc accaactgct
     4981 tttaaagctg caaagtgtat aattgattca atattatttt ctttaaatac aacatgcatt
     5041 tcatctttat ttctgatatc aatattataa aattttactg gttttttaga taattccttg
     5101 attctatcaa ccactattga gttgctatta cttaagttat caactataac aacttcataa
     5161 cctgattcta aaagttctat tgctgtatgg cttcctatat atcctgctcc tccagctact
     5221 aaaactgcca ttgtaattac ctcttttcta atatttattt ttcacttact ttttttctca
     5281 tatagtccat taaatcatct tttaaatttt ctctctttag agcaaagtct attgttgcct
     5341 ctaaaaaacc aattttatct cccacatcat atcttctacc ttcaaagtta taagcataaa
     5401 tagcctcttg ttttccaaga gtttgaagtg catctgtcag ttgtatctct ccacctttac
     5461 caggtgtctg tttctctaat atgctaaata ttgcaggagt tattatatat cttccaagta
     5521 tagctatatc agatggagct tcttcaattg caggtttttc aaccatatct ttaactttat
     5581 atactctatc ttcgatatgt tttacatcca atataccata tttattagta tcttctttag
     5641 ctatcttttg aacacctaat acagttgttt tatactcatt ataagtatct attaattgtt
     5701 ttaagcacgg aacatctgaa tctactatat catcacctaa taatacggca aaaggttcat
     5761 cacctataaa actttttgca cagtaaattg catgtccaag accttttggc tctttttgtc
     5821 ttatataatg aatatttacc atatttgata tgtctcttac catttctaac atctctgtct
     5881 tacctttttg ctctagttct aactctaatt caactgattt atcaaaatga tcttctatag
     5941 attttttatt tctacctgtt attataagaa tttcttcaat tcccgattct atagcttctt
     6001 ctattatata ctgtaaagtt ggtttatcta ctataggaag catttctttg ggctgtgatt
     6061 ttgttgctgg taaaaatcta gttcctagcc ctgctgctgg tattattgct tttttaactg
     6121 tcatctgcat tttttcaccc ttcttcgtaa attttctatt gtaccaaatt aatataccat
     6181 atttatactt tttcttcaaa ctctatatta tcccaatatt taatgctata agataatata
     6241 aggtagatga aatttcatct acctttagtt ttataagtta atattgtatt gtttatattt
     6301 tatccaaaac ttatacaggt actaaatttc atctaagatg ccttttatat cactatctat
     6361 atcttcatct agataagaat ctaaatcttc taagtcaact tctagttctt gatatgtcat
     6421 atcaacactg acatcctcat ctatatccat ttctgatatt aattctccta aaatactatt
     6481 tccatcagaa tctaaaccac tatctatatc ttcatctata tagttttcat ttaaaatttc
     6541 atctaaatca atctcgtaat aaacttcatt atttttttca tcccctgagt ccaatcctaa
     6601 gaactcatag ttaaaagtcc aaacattgta tttacttgac atactttatt cctcctgtga
     6661 aaaacatatt ttcatctagt ttattggttc cataatcaac agagttatat attttttcaa
     6721 ttatgtcttt tcttctttct tttgtactat tatttaatgt caattgttta aatacatatg
     6781 tatttgttat tctctcgaat aatatttctt ttatactatc atcatcaata tttctatagt
     6841 ttttccacaa taactcaaat aacttaaaca tttccctact agtttcatct acataataag
     6901 gatacatatt ttctactaaa tggtttaatc ttgatatggc ttgttttaaa aatacatcaa
     6961 gacttgcact ttcactttct tttaacattc tataattgta tttcttctta tcttctcctg
     7021 aaattacaaa gatgatattg tctaaacttt tttcaacttc atttaaataa ctgcttatat
     7081 tatatgataa atcagacaat agatttttaa tctgcttaaa cacttgtaca tcaagtttag
     7141 tattatactt ttcaaacaaa tctatttctt gattttctaa tattcttggc atatatgctg
     7201 acaataaatc taaattgttt ctttgttctt gtatttgctt ataaagtgaa tttataactt
     7261 ctattcttat ttcatcattt aactcttttt ctaaaatctt atcaaattca gatttcatat
     7321 agtaaatatt tccaaagaaa ttaaatatta tcatatcatt catagcttta gaccaattct
     7381 tatatatcac ttcaatagaa ttttctttaa gtagaggttg ctttgcatat ataaatacat
     7441 cttgcataag tttttgaacc atacttttac ttaagtttaa aagtactttt tgattattaa
     7501 attttatttc cgtttctaca aaattagaat tttcgttttc aagttcttta ttaattacaa
     7561 tgtcttttat atcactattt tttatagata tgatttcttt ttgaaaagac tttagaatag
     7621 tcaagctatc gaaatcttct tgaataaaaa atggagcatg ttttaatgta tatcccacta
     7681 tttcattttc tatatctttt aggtcatcta tttgcataat ttctctattt ttatcattta
     7741 tatgtaggtt aaatacattt ttattatcat ataatattat atcttctcct aaatttaact
     7801 tagaacaatt atctttcgct gactttacaa tagtcttctt agatttctta tttataaaaa
     7861 ttaattggtc ttgatatttt actaaaagca tgtttgtgtt tttataatca aatccatcta
     7921 tatttcctga tatcttgcag aatactattt cacaatcttt aggaagattt cctatttttt
     7981 ggttatcttt aactctctca tttaaatcag atgggactac actatctata ttgttattaa
     8041 atatagatac agaccttact ataatcccct ctctttccat atgaaagtat cccttcaatg
     8101 acactctttt atcttctaaa atgtatcttt ctatatcatc aaaatttatt tcaaatctat
     8161 ttttcccact gataaatata aacttctcat tatctttatt aattccaccc atataaaact
     8221 tattgtcatc taaacttaat atagtcatat tatcctttag atagaatata aattctcttt
     8281 gacttttgca gattaaatca tattcatcca aagttatttt catagtcaaa tttgctgtaa
     8341 catttttact tgaattttca ctttttatgt aaaaaggcaa gttatttcca tagacaatta
     8401 tttgagaatc ttctaaaact gcctctaatt tttctttatt gtctgaaaaa ctatatatat
     8461 attttacacc tgtatcctca ttaacttcat ctgatttgct gattattata ttccctagat
     8521 ttgttatatg aagcttttta tattcttttg agtatctact tatgccacta agctcaaacc
     8581 catctgaaag ctcatatatg attttttctc ctaatttcaa cataccttca ccacctaaac
     8641 agaattataa gtattttata aaggtgaata aaatgtctca aaacaaataa tatttttttt
     8701 aatacttttt attctgagac atagtttctc cttttttata atgctctaag caccttcaac
     8761 tatttcttca taaagtttat ctaaatgttt aacatattca cgatatccag atttgttctt
     8821 taactcactt cttaaatctt catatttttg tttaagttct tcagcactca aagaaggagc
     8881 tgattctttt aattcttcta acttataatc atagtactta tcatacatag ctatatatgt
     8941 atcaatagac ttcttagcta gttcattaca tttttcttgt gcttctccat attgagaata
     9001 atcacctatt tttattttat agtatccatt ttcttgaatt attgttgaag aaataccttt
     9061 agcttcatat tcttttgctg tttcttttgc tgttttttca actttaagtg aacctgcata
     9121 aacagtgtaa tatacacctt taccatcttt atatgcttcc atttcttttg ctttcttttc
     9181 agcttgtgct ttttcttgag cctctttttc agcttttgcc ttttcttctg cttctttttt
     9241 ctctttttca gcttgtgctt ttttctcttc ttcagttaat ttattgttag cttgttgttg
     9301 agttgatgac tttggaatat tctctttatc atttttctta ttgttgccta ctgttataaa
     9361 atatcctaca ccaacaataa ccactataac tactgctata atagtttctt ttaatctact
     9421 cttcttagaa acaacctctt catcatctaa agaatcttct ttatctgata cataattttt
     9481 catttctttc ttgttttctc tatatttgtc cttagaagaa tttttagatt ttttattact
     9541 attttctttc tttttaatag gtattactac tgatttttca ttttctaatt tttcttcttt
     9601 tatttctttt gcttttttat cttctaagtt tttactttct ttttcaagct tcgattcatt
     9661 atttgaagat actttttcat ctaagttatt atttattggt ttttctattt ttacactacg
     9721 ttcttcttct atatgttgac ttggttcttc ttgttttatt tctttcaatt cattttgctc
     9781 tatttcttct gatttcactt gatgattttc aactggttta tctaaaatta tatctggaga
     9841 aatatcattt aaattctctt cttcttgttc agcttcttca ttgtcttttt taataaatcc
     9901 aaataattta gccttctttt tactcttttt attttctggt tcaattatat cttctttatt
     9961 gctgtcgtac tctttatctg tagtatcttt atcttctaca acgtcaccta tatcttgatt
    10021 attactatct acttcttctt tagtcccttc ttcagcatca tcttctattg aaatactact
    10081 tctaaagcaa atatctttat ctgcattttt tatcatgtaa atgtattctt caatatcgat
    10141 atctttattt cttctagttc tttttgatgc aatttcatga ttttctaatt cactatagtt
    10201 atcttttatt agattctgtg ctttattcca tgtatcttca ctaatttctg ttttattttt
    10261 aattacatag tccacaaatt ccttaaaatt ttcaggacca aattctccaa ttatagtcag
    10321 tctcattgca ccttctataa ggtctctatt tcttctcttt aaaaattcta atacaactgt
    10381 tgcacaagca aaatctttaa taatttcttt gccaaaacca tatgcttcaa cagaatgaag
    10441 ttcttctaat ccacataact tcttatattc attgtgtatt gtttgagata tactttcatt
    10501 atttaagcta tttaacttat ctataaactt cgattctata tcatttgatt ttgattcatg
    10561 ttttactttt gaatttttaa tttcatttag tagcatgtca ttttctgaat tatctttacc
    10621 taattgcaaa tcctcaattt cagttgcttt tatttctact ttgttttgtt cgttattctc
    10681 ttccacatta ttaggtacca catctttatt actagctaat attttgttta cacagaatat
    10741 aatttctctt tttaattctc ttttcgcatc tgcttgattt ttaagaaata aatctccaca
    10801 ttctttcttt tctaaactta tttttctaag agatatatta agaaggtctt tatataggtt
    10861 taaaacctta taatcctttt ctaaacgtct tcttctctct gatagttcca ttttatcata
    10921 agctaaaaaa ctatttaaat cattggcttt tagagagtct aatccctctt tcatagcctt
    10981 atttacatac tttctacatt ttgctgtagt taactctaaa tctttttcta attcatctat
    11041 ttcaggtatg tacttatcta ctatccattt gccaataagt ggttctgtat ttcttgctaa
    11101 tgtcttataa aacaatatat taaattttaa aagctctgca tattttgctt cattaaattc
    11161 tactttttca aatttctttt ccaaaacacc atctagcttt tcatttattt tagactcttg
    11221 ttttaaaaaa cttgctgtga catttaaaac agtgtttctt attatattat tttcactcaa
    11281 aaccttcact ccttaaatca attattttat tgtaatattt acattgtgca aagttgctaa
    11341 tttgattatg atatctaaat aattatttac taaatttgct acatcttata tcatatcata
    11401 ttatttacat cattttactt tttcttttta tatctatctt atattatacc atttttaata
    11461 tctgtactaa cttatattac aatattcctc aaaattttaa aagtagatta gacaaattta
    11521 caaataaaaa aacatcagtt taaactgatg tttttgacta tcgaaataat taagcaagtc
    11581 tataagcgga gttctgtatt agataatcat ctttctaggc ctattgtcac caataggctc
    11641 aagcgaccta cctaccggag agtacgagca gcactcttta ttcctatctt ggtcttgctc
    11701 caggtggggt ttacatagcc aactagtcgc ctagctgctg gtgagctctt acctcgcctt
    11761 tccatcctta ccacaatagt ggcggtttat ttctgttgca ctatccttag gatcgctccc
    11821 actaggcgtt acctagcacc ctgctctatg gagctccgac tttcctcatg taagattaca
    11881 tgcgattatc tggcttactt aatatttatt ttacttagtt atgttaacac aaattctttt
    11941 acatgtcaaa gtaatattat actaaaaatt taaatttatt caaaaatagt gtaatataga
    12001 tatataaact acatttaact cgaggtgatc tattgaaaaa attatataga atagtaatta
    12061 acattatact agtattagta atactttaca gtggatttaa tatatactca aaacttacca
    12121 aatacaatca tgatactaaa atatcctcag aacttcaaaa aaaagaatat aaaaaagagg
    12181 atttatcaaa gattaacagt gattttaaat tttggctttc tgttgagaat acaaatataa
    12241 attatccagt tgtacaatct aaagataatt cttactatct tgacaaagat ttttataaaa
    12301 aagattctat ttctggtaca ctgtttatgg attatagaaa taaatctatt gatgacaaaa
    12361 atatcataat atatggacat aatatgaaaa ataaaactat gttcaacaac ctaaataagt
    12421 ttaaagatgc tgacttcttt aaaaaaaata ataaaataaa aataaccttg aatggaaaag
    12481 aatttttata tgatgttttt tctgcttata ttgtagaatc tgattatgat tatctaaaaa
    12541 caaattttaa caatgaatct gattatcaaa attacataaa tgatattact tctaaatcat
    12601 tgtataaatc tcctattaag gtaaatagca atgataaaat agttacactt tctacatgta
    12661 cctatgaatt tgatgatgcc agaatggtga ttcatggtag attgatttaa aactcacaga
    12721 cacagtttaa aacaataatt ttaaactgtg tcatctttta tacctataat ttgtaaatta
    12781 gaccactaaa agtatttaat acaaaataac aaatacatca aacaataaaa aacaataaaa
    12841 aaagactatg ctaaaaacat agtctttact ggagctggtg ataggaatcg aacctacaac
    12901 ctgctgatta caagtcagct gctctaccgt tgagccacac cagcacacct attttattgt
    12961 aaattagcaa aactaatttt taaaagtta
//
LOCUS       DAJMZY010000116        12953 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.117, whole genome shotgun sequence.
ACCESSION   DAJMZY010000116 DAJMZY010000000
VERSION     DAJMZY010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12953)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12953)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12953
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.117"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            204..1400
                     /locus_tag="OE968_003187"
     CDS             204..1400
                     /locus_tag="OE968_003187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HCP7220431.1"
                     /translation="MNYSNRVSAMQASPIRKLVPFAQAAKDKGIKVYHLNIGQPDIKT
                     PKGFFDAVKNFDSEVLEYATSEGIPELLEALQNYYKTYDMNFEKDELLVTNGGSEALL
                     FTMMAVCDPGDNLLVPEPFYTNYNGFGQSVNVEVNAVTTKAENGFHLPSKEEILSKVD
                     DKTKAIILSNPGNPTGAIYTKEELNILAEIAKEKDLWIIADEVYREFVYDGLEYTSCG
                     NLEGVQDRVIIIDSVSKRYSACGARIGSIACKNKGLIAQILKLCQGRLCVPTLEQIGA
                     VELYKTPVSYFKEVNEEYKKRRDVLYNELMKVEGVICKKPTGAFYIVAKLPVENAEDF
                     TIWMLKEFNKDNETVMVCPAEGFYATPGLGRDEIRLAYILNEKDLHRAATLLKEGLEQ
                     YVALQK"
     gene            complement(1512..2852)
                     /locus_tag="OE968_003188"
     CDS             complement(1512..2852)
                     /locus_tag="OE968_003188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-alpha-glucosidase"
                     /protein_id="HCP7220432.1"
                     /translation="MKKRYNIAIVGGGSTWTPGLLKSLCKMSDRFPLNKVTMLDVVEE
                     RQRLIGEFGKILFKEEYPKATLEYTTNPDEAFIDVDFVFVQMRTGGLKMRELDEKIPL
                     QFGLVGQETCGAGGFAYGLRSIGDMIEMVKTVRKYSPKAWILNYTNPAAIVAEALKRV
                     FPDDKRLLNMCDQPVNLLRSYGRLLDMDSRTFEPVYFGLNHFGWFTHLYDKNGEDLVP
                     KIKDLVANSGFQPVDAEQRDKSWLDTYGMVKDMLEDVPDYLPNTYVQYYLYPDKKVAK
                     SNINCTRAREVMNGREKRVFEECKSVIEKGTSIGSNLVHNDAHGEFIVEVAEAIAHNK
                     HQIAIVITENNGAISNLPDDAMVEVAAILTKNGPRPLHVGNIPTFYKGLLEGQLAYEK
                     LAVDAYFEQSYEKAILSLTLNRTIISPTKARQVLDALIKVNKDYWPTLYKENEK"
     gene            complement(2991..3743)
                     /locus_tag="OE968_003189"
     CDS             complement(2991..3743)
                     /locus_tag="OE968_003189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HCP7220433.1"
                     /translation="MNLIDKLDINQKKLSTNEISLLNYFLKNSEKINQKKIKDIANET
                     FNSTAYIVRFCQKLGFSGYSEFKNFLVFSYSNRNERNKEFTKSQSDIFTDVMDTQNLI
                     NVENIDMCLNEIHNSKHIYFFGVGSSRLVCTEMSQRFSAIGVNVKYYDDSTLMYLAAS
                     NITKDDLVIAVSMSGETAQVIKACNIAKTNQVKVISLTNISVNSLSNIADIKLFVSSP
                     QYNFNSVNYTSRVPALSLMEYMFHKYIEKYNR"
     gene            complement(3891..5468)
                     /locus_tag="OE968_003190"
     CDS             complement(3891..5468)
                     /locus_tag="OE968_003190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HCP7220434.1"
                     /translation="MKQKMKGFFLQLGKSFLLPIALISAAGIFLGISSAFSNPNIVSD
                     MPFLANNFIQGILGFTKAITGVLFGNLAIFFAISISVGLAKEEKAVSAFSGFVGYLVL
                     HTSVNYMLGCRGIIAEPDMMREMGQAVTLGIQTLELGVFGGIVVGIITASLHNKYYNI
                     KLPDYLGFFGGTRFVPIITTVVFSILGIIIPYIWPYVNTIIQSVGIGIASLGYLGTFV
                     FGFLERLLIPFGLHHILNAMFRFTEVGGSLVVGGQEVFGALNIFLAQLSDPETISFST
                     EATRFLAQGKIPIMVFGLPAAAYAMYKTAKPENRSKVKGILLAGALATFVTGITEPLE
                     FSFLFVSPILFVIHAFLSGISFMMMHIFGVAIGNTQGGIIDLVVFGVMQPNTKWIYSI
                     ILGLVYAIVYYNVFKILILRFNLQTPGREEITDINFDLKPLSNKVEIAQSGETTKRAL
                     SIIKYLGGKDNIEDITNCITRLRVVVKDMSKVDENAFKKYTGAMGVIKVSDKDIQIIY
                     GPSVSQVRDEVSFAMSI"
     gene            complement(5880..6332)
                     /locus_tag="OE968_003191"
     CDS             complement(5880..6332)
                     /locus_tag="OE968_003191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HCP7220435.1"
                     /translation="MNYIVKDTISFLVKTFPKIYSSLYLEDLKKFAPDYNVNKTQLRA
                     LVFIKNYGVISMTDLCSKLNIEKGSLTSMVDDLTDKKYVTRKRDLVDRRKYLIDITEE
                     GDKIATDFMDKLSDGLGEKLSKLTEEDRKKYLEAINTLQYILNKEEFR"
     gene            complement(6643..8088)
                     /locus_tag="OE968_003192"
     CDS             complement(6643..8088)
                     /locus_tag="OE968_003192"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HCP7220436.1"
                     /translation="MIDNKYTTYSNPLTDRYCSKDMSYIFSPQFKFSTWRRLWVALAE
                     GEHELGINITEEQLDELRANIDNINFDEARKIEKEVRHDVMSHVKAYGLQCEKAKGII
                     HLGATSAYVGDNTDVIQMNEALKLLRVKLVNLINNLKEFALKYKDMPALGFTHFQAAQ
                     LTTVGKRACLWAQDLILDLEDLNYRIDNMKLRGVKGTTGTQASFLSLFEGDHEKVKEL
                     DKKICKKMGYHSSYAVSGQTYTRKLDYQVISILSGIAQSMHKMTNDIRLLQSLKELEE
                     PFEKNQIGSSAMAYKRNPMRSERIASLSKYIISESISPAMVQATQWLERTLDDSANKR
                     LAIPQAFMAADAILEIGINVTDGLVVYENMINRRVNEELPFMATETILMEAVKRGGDR
                     QELHEIIREYSMKAAYRVKHEGKDNNLIELIMNDDSFKMSKEEILSIMDPKNFIGRAP
                     EQVVEFVNEVVEPAIKDYKEDLGKVDVDLRV"
     gene            complement(8232..9140)
                     /locus_tag="OE968_003193"
     CDS             complement(8232..9140)
                     /locus_tag="OE968_003193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HCP7220437.1"
                     /translation="MYSTKILDDYEYETFNVFSTKLNPNTKHDYLSKVILFKEFLKGK
                     ELIYATKEDCKNFVDYIQTKYAKSTCEKIYSYLHSFYNFLKKEGYIDINPFRYVEKPT
                     VTRIKTKDDVLSIQEINKLIGILPKLNIRDRVIIVCLVTTGCLLNELVSLKWKDLMVD
                     ENDNSYVRLGKGRKERVVKLHPYFFKLLEDYRNYSGLPEVIIPSDDFIFTTQKSNSIT
                     DRNVRLIVKKALDLAGLSQYSARDFRHSFAAISLRLGADESDVKNQLGWSDKYYAIRY
                     KYVLNFVDSEIVDYLIEKDNLDINKK"
     gene            9397..10221
                     /locus_tag="OE968_003194"
     CDS             9397..10221
                     /locus_tag="OE968_003194"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HCP7220438.1"
                     /translation="METFSLLEIFKAVILGIVQGITEWLPVSSTGHMILVDEFIKLNF
                     SNTFISTFLVVIQFGSILAVLVIFFRKLNPFDSAKNIKQKKETVRLWLKVIIAVIPSG
                     VIGILFEDDIDRLFFNSTVVAIALIVYGIIMIGLEKRNKKPKYKDFSQVTYKLALCIG
                     LFQCLALIPGTSRSGSTIIGAVLLGTSRYVAAEFSFFLAIPTMLGASALKLLKAGFGF
                     TGFEWLILGVGSVVAFVVSIVVIKFFMDYIKKHDFKVFGYYRIVLGIVVLAYFFLL"
     gene            10261..10791
                     /gene="lepB"
                     /locus_tag="OE968_003195"
     CDS             10261..10791
                     /gene="lepB"
                     /locus_tag="OE968_003195"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HCP7220439.1"
                     /translation="MSVKKEIFDWIKSIAMAIVLAFVILQFIRPSIVSGESMYPTLDD
                     KDYLILNRISYKVGKPEKGDIVVFKTNLVDGETGKKKDLIKRVIATEGDRIKISNSKV
                     YVNGKLLNEPYIHNNYTSGDIDTVVPKGKLFAMGDNRENSNDSRFPDVGMVDEDEVLG
                     KVMVRLLPLDNIGKVD"
     gene            complement(10873..12654)
                     /locus_tag="OE968_003196"
     CDS             complement(10873..12654)
                     /locus_tag="OE968_003196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UvrD-helicase domain-containing protein"
                     /protein_id="HCP7220440.1"
                     /translation="MSQYININSQLDALKLKEFEKIFYENINEDVKVVPKVTPFKGIN
                     TDLLYVKDGRILFIKFMDTTEDIFFILEEELLEVMNEEYELLKLKMGQKNRNISYNYV
                     YIMPYVEVEETYEFEEFVNNNIIDKNKLQDIMNKGSLEEYLNDENDEINLNLFLLDIC
                     SEYYIINDKLHLNEKFKKISFYNDDYKYTATMMEDVQIKDVVSIKYGNTLIEGGSGIG
                     KTAIMLSRAIKLAKVYPHHKLVIFTHTKQLCNELRERIELLYKDNNNLEVHTFSSFIF
                     KLAKKFNLIVDYNMLKNDYEKTFNNLVKQAQNIIKNKNMFKAIFIDEAESFLEYEIDF
                     IREFLYKTKFIFNVCSCNSLNISNRLNIFKKLYNGIEFDDKIILSKNYRQAKEIVDFT
                     NKFSNNSNSYINELRPNTEFSTFFYTKALRGGNKSVDIIKVSDLDDQISSVIWEIEYL
                     ISKKGLDYSEVAIVYPYNKKKLKSGKTIYFQYMLKKALEEAKIPYICAEDNLTNISKK
                     VGTTIANIYAIKNLEYKAVIVCELEMLYNQTINDIEQDYQVNDFVGDLNKVYLAMSRA
                     TDYLSIVTTFNEEASDIIRLITESKDI"
BASE COUNT         4363 a         1975 c         1582 g         5033 t
ORIGIN      
        1 taatttatga atacataatt tagtggcata aacatgggta ttttactata atttgttaaa
       61 agtttatttt aaagctatat taattttttt tgatgatttt tacccataag tatgttatta
      121 ttatcttgta aagatgtctt gtattcaaac atacaattta cataatacaa tatacgtatt
      181 taaattaaat agggggtatt aaaatgaatt attcaaacag agttagtgca atgcaagcct
      241 ctccaatcag aaaacttgtt ccatttgcac aagcagcaaa agataaagga atcaaagtat
      301 atcacttaaa cataggacaa ccagacataa aaactcctaa aggatttttt gatgctgtta
      361 aaaactttga tagcgaagtc ttagaatatg ctacatcaga aggtattcca gaattattag
      421 aagcacttca aaattactat aaaacttacg atatgaattt tgaaaaagat gaattattag
      481 taactaatgg tggtagtgaa gctttacttt tcactatgat ggcagtttgt gacccaggag
      541 ataatctatt agttccagaa ccattctata caaactacaa tggatttggt caatctgtaa
      601 acgtagaagt taatgctgtt acaacaaagg cagaaaacgg tttccacctt ccatctaaag
      661 aagaaatatt gtctaaagta gatgataaaa ctaaggctat aattctttct aacccaggaa
      721 atccaactgg tgcaatttat acaaaagaag aacttaatat cctagctgaa atagctaaag
      781 aaaaagattt atggataata gcagatgaag tttatagaga atttgtttat gatgggcttg
      841 agtatacaag ctgtggtaac ttagagggtg tacaggatag agttataata atagacagtg
      901 tttctaagag atacagtgct tgtggtgcta gaattggttc tatcgcttgc aaaaataaag
      961 gtcttatcgc tcaaatcctt aaattatgtc aaggaagact ttgtgttcct acattagagc
     1021 aaataggagc tgttgagtta tacaaaactc ctgtttctta cttcaaagaa gttaatgaag
     1081 agtacaaaaa aagaagagat gtattataca atgaattaat gaaggttgaa ggtgttatat
     1141 gtaaaaaacc aactggtgct ttctatatag ttgctaaatt accagttgaa aatgcagaag
     1201 atttcacaat ttggatgtta aaagaattta acaaagataa tgaaacagtt atggtttgcc
     1261 ctgctgaagg attctatgct actccaggtt taggacgtga tgaaataaga ttagcttaca
     1321 tcttaaatga aaaagacctt catagagctg ctacattatt aaaagaaggt ttagagcaat
     1381 atgtagcttt acaaaaataa ttttttaaac ttaatttata taaatttaat gatataaaat
     1441 gtcccctttt cagatattat ttgaaaaggg gacatttctt aattaatata ttaattaaga
     1501 cttagacctg actatttttc attttcttta tatagtgttg gccagtaatc tttattcact
     1561 ttaattaaag catctaaaac ttgtcttgcc ttagttggag agattatagt tctatttaat
     1621 gttaaagata aaatagcttt ttcataagat tgttcaaagt atgcatcaac tgctaacttt
     1681 tcataagcta gttgaccttc taacagtccc ttataaaatg ttggtatatt acctacatgt
     1741 aaaggtctcg gtccattctt tgtaagaatc gcagctactt ctaccattgc atcatcaggt
     1801 aagttgctaa tagccccatt attttctgtt ataactatgg ctatttggtg tttgttatga
     1861 gctattgctt ctgcaacttc aactataaat tccccatgag catcattatg cactaaatta
     1921 gaacctatag atgttccttt ttctataaca gatttacatt cttcaaatac acgcttttct
     1981 cttccattca taacttctct tgctctagta caatttatat ttgatttagc tactttttta
     2041 tcaggatata gataatactg tacatatgta ttaggtaagt aatctggtac atcttccaac
     2101 atatctttaa ccattccata agtgtctaac caagatttat ctctttgttc tgcatcaaca
     2161 ggttggaatc cagagtttgc tactaaatct tttatcttag gtaccaaatc ttcaccattt
     2221 ttatcataca aatgtgtaaa ccatccaaag tgatttaatc caaagtatac aggctcaaat
     2281 gttcttgaat ccatgtctaa caatcttcca taagacctta acaagttaac tggttggtca
     2341 cacatattaa gtaatctttt atcatctgga aatactcttt ttaatgcttc tgcaacaata
     2401 gcagcaggat ttgtataatt taatatccat gctttaggag agtattttct tacagtctta
     2461 accatttcta tcatatcacc tatagacctt aacccataag caaatccacc agctccacaa
     2521 gtttcttgac caaccagtcc aaattgtaga ggaatctttt catctaattc tcgcatctta
     2581 agaccaccag ttctcatttg aacaaataca aaatctacat ctataaatgc ttcatctggg
     2641 tttgtagtat attcaagtgt tgctttagga tattcttctt taaataatat ttttccaaat
     2701 tcccctatta atctttgacg ttcttctact acatctaaca tagttacttt atttagagga
     2761 aatctatcac tcattttaca taaagacttt aaaagtcctg gagtccaagt actgcctcct
     2821 ccaactatag ctatattgta tctttttttc attgtcatat taatcacccc tgttttttat
     2881 taactaactt gtaagatgat tataatatat aaagttttct acatgaatac ttttaggtaa
     2941 tcattaaaaa tagttcaatt ttagtatttt tttcaaaatt gtaatttttt tcatctattg
     3001 tatttttcaa tgtatttatg aaacatatat tccataagag aaagtgctgg cactctagat
     3061 gtatagttaa cactattaaa attatattgt ggagaagata caaataattt tatatcagct
     3121 atatttgata atgaattgac acttatattt gtcagagaaa ttactttaac ttgatttgtt
     3181 tttgctatat tacatgcctt aataacttga gcagtctctc cagacataga tacagcaatt
     3241 acaaggtcat ctttagtaat atttgatgca gccaaataca tgagagttga atcatcatag
     3301 tattttacat ttacacctat agctgaaaaa cgttgagaca tttcagtaca tactaatcta
     3361 gaagacccaa caccaaaaaa atatatatgc ttagaattat gtatttcatt taaacacata
     3421 tctatattct ctacatttat taaattttgt gtatccataa catcagtaaa aatatcactt
     3481 tgacttttag taaactcctt atttctttca tttctatttg aatatgaaaa aactaaaaag
     3541 tttttaaatt cactatatcc agaaaagccg agcttctgac aaaaccttac tatgtatgca
     3601 gtcgaattaa aagtttcatt tgctatatct ttaatctttt tttgatttat tttttcagaa
     3661 ttttttagaa aatagtttaa aagagatatt tcatttgtag ataatttttt ttgatttata
     3721 tctaatttgt ctattaggtt catttatacc tccataataa tgatttgtag ttaaacaact
     3781 ttctcatatt tattatataa atatacacta tacagcattt atcttatgtt tattatacta
     3841 taaaaaagac aatacaaatt ataaattagt attgcctttt aatatttact ttaaatagac
     3901 attgcaaaag aaacttcgtc tcttacttga gatacagatg gcccataaat tatttggata
     3961 tctttatcag atacttttat aactcccatt gcacctgtat attttttaaa agcattttca
     4021 tctactttac tcatatcttt aactactact cttaagcgag ttatacagtt tgttatatct
     4081 tctatattgt ccttaccacc taaatattta attatagata atgctctctt agtagtttct
     4141 ccactttgag ctatttctac tttatttgat aaaggtttta aatcaaaatt tatatctgtt
     4201 atttcttctc gtcctggagt ttgtaagtta aatctaagta tcaaaatctt aaatacatta
     4261 taataaacta ttgcatacac taaaccaagt attatagaat aaatccactt tgtatttggt
     4321 tgcataactc caaatactac taaatctatt atgccacctt gagtatttcc tattgctact
     4381 ccaaatatat gcatcatcat aaatgatata cctgataaaa atgcatgtat aacaaataat
     4441 attggtgata caaataagaa tgaaaattcc aatggttccg taattcctgt tacaaatgtt
     4501 gctaaagcac cagctagtaa tataccttta accttcgacc tattttcagg ctttgcagtt
     4561 ttatacatgg catatgcagc agcaggaaga ccaaatacca ttataggtat tttcccttga
     4621 gctaaaaatc tagttgcttc tgttgaaaaa ctgattgttt cagggtcact tagttgagct
     4681 aagaatatgt tcaatgctcc aaatacttct tgccctccca caactaaaga acctcctact
     4741 tcagtaaatc taaacatagc atttaatata tgatgtaatc caaatggtat taaaagtctt
     4801 tcaagaaatc caaatacaaa tgttcctaaa tatcctaaac tagctatacc aatacctaca
     4861 ctctgaataa ttgtatttac atatggccat atatatggta ttattatccc caaaatagag
     4921 aatactactg ttgttattat tggaacaaac ctagttccac caaagaatcc taaataatct
     4981 ggcagtttta tattatagta tttattatgt aatgatgctg ttattatacc aactacaatt
     5041 ccaccaaata ctcctaattc taatgtttgt atgcctaaag ttacagcttg acccatttct
     5101 ctcatcatgt caggttcagc aataatcccc ctacacccta acatataatt tacactagtg
     5161 tgtaatacta aataaccaac aaaaccagaa aatgcagaaa ctgctttttc ttctttagca
     5221 agaccaacag atattgatat agcaaagaat attgctaagt ttccaaaaag tactcctgtt
     5281 atagcttttg taaaacccaa tattccttga ataaaattat ttgctaaaaa aggcatatca
     5341 ctaactatat taggatttga aaatgctgaa cttattccta aaaatatacc tgctgcagat
     5401 attaatgcta ttggcaataa aaatgatttt cctaactgta aaaagaaccc tttcattttt
     5461 tgtttcattt ctatccctcc atttttaaat ttttaaaacg ttttctatgt cataattata
     5521 tatttttatt ttgtttttga aactttataa tttgttttaa aatattttta cataaatagt
     5581 aattttttca aaactgtaaa ttttttcaaa caaagacata gtaacgttgt aacatatata
     5641 aatttaaaaa gagcttagaa aataaaatta ttgaatataa aatggaaaaa tataaattac
     5701 acaaagagat atgagtacgt actaacaaat acgaaaatgt ataagaaatt ataaaaaagt
     5761 acatcaagaa aatttaagat gtacttttta gattgtattt agacttataa ttatatagtt
     5821 aaatgaataa caaagaatta atcttagtac tattaaatac aaaaattttt atattttttc
     5881 tatctaaatt cttctttgtt taatatatat tgaagagtat ttattgcttc taaatatttt
     5941 tttctgtctt cttcagttaa tttagaaagt ttttctccta aaccatcact taatttatcc
     6001 ataaaatcag ttgctatctt atctccctct tcagtaatgt caattagata ttttcttcta
     6061 tcaactaaat ctcttttcct tgttacatac ttcttatcag ttaaatcatc aaccatacta
     6121 gttaaactgc ctttttctat atttaactta gagcataaat cagtcatact tattactcca
     6181 taatttttta tgaaaactaa tgctcttaat tgtgttttat ttacattata atctggtgca
     6241 aattttttta ggtcttctaa gtacaggcta gaataaatct taggaaatgt ttttactaaa
     6301 aaacttatgg tatcttttac tatatagttc atataatcac ctcggttgtt ttaaaattta
     6361 ttaaattatc taaataactt tatttcagtt tacattaaaa atattgcaag tacaatagtt
     6421 tttgctgaat gtttaaattt aattagtaat cttatcattt ttttattttt atttatatta
     6481 ttcctattaa atattattta tatagctatt ttattaaatt catggtatag taagtaaaga
     6541 agaactcttc acagcggtgg agagaagacg ctagcccatt aaaatggcta tcttatttat
     6601 aaataagata gccgttttta attatatttt atctgtacaa ttctatactc ttaagtctac
     6661 atctactttt cctaagtctt ccttataatc ttttatagca ggttctacaa cttcatttac
     6721 aaattctaca acttgttctg gagctctacc tataaagttt tttgggtcca ttatagatag
     6781 tatttcttcc ttgctcattt taaatgaatc atcattcatt ataagttcaa ttaagttatt
     6841 atccttgcct tcatgcttta ctctataggc agctttcata gaatattctc ttattatttc
     6901 atgtaattcc tgtctatctc cacctctttt tacagcttcc ataagtattg tttctgtagc
     6961 cataaaagga agttcttcat ttacacgtct atttatcata ttttcatata ctactaaacc
     7021 atcagttaca tttatcccta tttcaagtat agcatctgct gccataaatg cttgaggtat
     7081 tgccaatctc ttattggctg agtcatctaa tgttctctct aaccattgag tggcttgtac
     7141 cattgcaggg cttatagatt cagagattat atacttagat aaagatgcta ttctctcact
     7201 tctcattgga ttcctcttat aagccattgc tgatgaacct atttgatttt tttcaaatgg
     7261 ctcttctaat tcttttaaac tttgtaaaag tcttatatca ttagtcatct tatgcatact
     7321 ttgagctatc cctgatagta tgcttattac ttgataatct aactttctag tatatgtctg
     7381 tccacttact gcataggaag aatggtatcc catcttttta caaattttct tatctaactc
     7441 ttttactttt tcgtggtctc cttcaaataa gcttaaaaaa cttgcttgag taccagtagt
     7501 acctttaact cctcttaact tcatgttgtc tattctatag tttaaatctt ccaaatcaag
     7561 aattaaatct tgagcccata aacaagctct ttttcctact gttgtaagtt gagcagcttg
     7621 gaagtgtgta aatccaagag ctggcatatc tttgtactta agtgcaaatt cttttaaatt
     7681 gtttattaaa tttacaagct ttactcttag aagttttaaa gcttcattca tttgtataac
     7741 atctgtatta tctccaacat atgcagatgt tgctcctaaa tgtattattc ctttggcttt
     7801 ttcacattgt aaaccataag cttttacgtg agacattaca tcatgtctta cttctttttc
     7861 tatttttcta gcttcatcaa aatttatatt atctatatta gctcttagct catctaattg
     7921 ttcttcagtt atattgattc ctaactcatg ttcaccttct gcaagtgcaa cccataacct
     7981 tctccatgta gagaatttaa attgtggaga aaatatataa ctcatgtcct tgctacaata
     8041 tctgtctgta agtgggtttg agtaagtagt atatttatta tctatcatta tattagcacc
     8101 ttccttaaat cttttgtcgt gtgattactg tgtacacatt agtacataaa taattatata
     8161 taattttacg aactataaca agactttttt attttttgtt cacatttata tatagtattt
     8221 tttatttatt actatttttt atttatatcc aaattatctt tttcaattaa gtaatccact
     8281 atttcactat caacaaaatt taatacatac ttatatctaa ttgcatagta tttatcactc
     8341 catccaagct gattttttac atcactttca tctgccccaa gccttaaact tattgctgca
     8401 aatgaatgtc taaaatctct tgctgaatat tgagaaagtc cagctaaatc taatgctttt
     8461 ttgactataa gtctgacatt tctatctgtt atagaattac tcttttgagt tgtaaaaata
     8521 aaatcatcac taggtattat tacctctgga agcccagaat aattcctgta atcttctaaa
     8581 agtttaaaaa agtatggatg taatttaact actctttctt ttcttccctt acctaacctt
     8641 acatatgagt tatcgttttc atctaccata aggtctttcc actttaagct aactaattca
     8701 tttaataaac acccagtagt aactagacag actattatta ctctatctct tatatttaat
     8761 tttggtagga tacctataag tttatttatt tcttgtatac ttagaacatc atcttttgtt
     8821 tttattcttg ttactgtggg tttttctaca tatctaaatg gatttatatc tatgtatcct
     8881 tcttttttta agaagttata aaaactatgt aaataactat atatcttttc acaagttgat
     8941 ttcgcatatt tagtctgtat atagtctaca aaatttttac aatcttcttt cgtagcataa
     9001 atcaattctt tcccttttaa aaattcttta aacagtataa cctttgataa ataatcgtgt
     9061 ttcgtgtttg gatttaattt tgtagaaaaa acattaaaag tttcatactc ataatcatct
     9121 agtatttttg tactatacat aataactcct ttccttttca taaaataaaa tagctatact
     9181 tttactatac catatatttc cccctcaaat atacccctta ttcaatagat aacttttaag
     9241 tttattttgt tatattgtga aggttttatg aaaatatcaa tcttccattg tgcactacac
     9301 agtactatgg tattataagt tagtaaaagg tggcattttt ttattaatct atgaataaaa
     9361 tatgctacta taaatttgta ttggaggtat tttgatttgg aaacatttag tttgcttgaa
     9421 atttttaagg cagtcatttt gggcatagtt cagggaataa cagaatggct accagtaagt
     9481 agtacagggc atatgatatt agttgatgag tttataaaat tgaatttttc aaatacattt
     9541 ataagtacat ttttagttgt aattcaattt ggttcaatat tagctgtact tgttatattt
     9601 tttagaaaat taaatccttt tgatagcgca aagaatatta agcagaaaaa agaaacagtc
     9661 cgtttatggc ttaaggttat aattgcagtt ataccatctg gagttattgg aatactgttt
     9721 gaagatgata tagatagatt attctttaat tcaacagtag ttgctattgc tcttattgta
     9781 tatggtataa taatgatagg gcttgaaaag agaaataaaa aacctaagta taaagatttt
     9841 tctcaagtta catataaatt agctctttgt ataggattat tccagtgtct agctcttata
     9901 ccaggtacat ctaggtctgg ttctactata ataggtgcag tattacttgg tacttctaga
     9961 tatgtagcag cagagttttc attcttctta gccatcccta caatgcttgg agctagtgca
    10021 ttaaaacttc taaaagctgg atttggattt actggatttg aatggcttat tttaggtgtt
    10081 ggttctgtag tagcatttgt tgtttcaatt gtagttatta aattttttat ggactatatc
    10141 aaaaaacatg acttcaaagt atttggttat tatagaatag tcttgggtat agtggttctt
    10201 gcttatttct ttctattata atgtattcta atttaataac aaatgataag gagaaaagtt
    10261 atgagtgtta aaaaagaaat atttgattgg attaagtcaa tagctatggc tattgtactt
    10321 gcatttgtaa ttctacaatt tataagacct tctattgtaa gtggagaatc aatgtatcct
    10381 actttagatg ataaagatta tctgatttta aataggatat catacaaggt tggtaaacct
    10441 gaaaaaggcg atattgtagt ttttaaaacc aatttagttg atggagaaac aggaaagaaa
    10501 aaagacttaa taaaaagagt tatagctact gaaggtgaca gaataaaaat atcaaattct
    10561 aaagtgtatg taaatggaaa attattaaat gaaccatata tacacaataa ctatacttct
    10621 ggagatatag atactgttgt tccaaaaggt aaactatttg caatgggaga taatagagaa
    10681 aatagtaatg atagtagatt ccctgatgta ggtatggttg atgaagatga agttcttggt
    10741 aaggttatgg tgagactatt acctcttgat aatattggga aagtagacta aaaaataaga
    10801 gactgaattg gtaaagttta ttttacaaat ctcagtctct ttttattttc ttaaattaca
    10861 aatatttttt tactaaatat cttttgattc tgtaataagt cttattatat cacttgcttc
    10921 ttcattaaaa gttgttacta tacttaggta gtctgttgct ctactcatag ctaaataaac
    10981 cttatttaaa tctcctacaa agtcatttac ttgataatct tgttcaatat catttatagt
    11041 ttgattgtat aacatctcta attcacatac tattaccgct ttatactcta aattctttat
    11101 tgcatatata tttgctattg tagttcctac cttcttactt atatttgtca aattatcttc
    11161 tgcacatata taaggaattt ttgcctcttc caatgctttt tttaacatat attgaaagta
    11221 aatggttttt ccacttttta atttcttctt attgtaagga taaacgatag caacttcaga
    11281 ataatcaaga ccttttttac ttattaaata ctcaatttcc cagattacag aacttatttg
    11341 gtcatcaagg tcacttactt ttattatatc aacagactta tttccacctc taagtgcttt
    11401 agtataaaag aaagtactaa attctgtatt tggtcttaat tcgttgatat atgagttaga
    11461 attatttgaa aatttatttg taaaatctac aatctcttta gcttgtctat aatttttact
    11521 taagataatc ttatcatcaa attctatacc attatataat tttttaaata tattcaatct
    11581 attagagata ttcaaggagt tacaagaaca cacattaaat atgaattttg ttttatataa
    11641 aaactccctt ataaaatcta tttcatactc taaaaagctt tctgcttcat caataaaaat
    11701 agccttgaac atatttttat tttttataat gttctgtgct tgttttacaa gattattaaa
    11761 ggtcttttcg taatcatttt ttaacatgtt ataatctaca attaaattga attttttagc
    11821 tagtttaaat ataaaagaac taaatgtgtg aacttctaaa ttgttattat ctttgtataa
    11881 taactctatc ctctctcgaa gctcattgca caattgtttt gtatgtgtaa atatgactaa
    11941 tttatgatgt ggatatactt ttgctaattt tatagcccta gaaagcataa ttgctgtttt
    12001 gcctatacca gaaccacctt caataagtgt attcccatat ttaatagaaa caacatcttt
    12061 aatttgaacg tcttccatca tagttgctgt atacttatag tcatcattgt agaatgaaat
    12121 ttttttaaat ttttcattta gatgaagttt atcatttatt atatagtatt ctgaacatat
    12181 gtctagtaaa aataaattta agtttatttc atcattctca tcattaagat attcctccag
    12241 cgaaccctta ttcattatat cttgaagctt atttttatct attatattat tattaacaaa
    12301 ttcttcaaat tcatatgttt cctcaacttc aacgtatggc ataatgtaaa cgtagttata
    12361 acttatattt ctattctttt gtcccatttt tagtttcaaa agttcatatt cctcattcat
    12421 aacttcaagt aactcttctt ctaaaataaa aaatatatct tctgttgtat ccataaattt
    12481 tataaataaa attcttccat ctttaacata caacaaatcg gtatttattc ctttaaaagg
    12541 agtaactttt ggcactactt taacgtcctc attgatattt tcgtaaaata ttttctcgaa
    12601 ctccttcaat tttagggcgt ctaactgaga atttatattt atgtattggc tcacttacat
    12661 tacctccttc tgttatactt aattatacca ttttgaacta tatttttata tatacttttt
    12721 ataggcaaat ttagtaaata aattcaaaat aaatacaaat aaatacaaaa ctgctaaaaa
    12781 aattttgcaa taagtataga tatttattgt tataaaatac tttctgtaaa taataaaatg
    12841 ataaatttca taattaatgc ttaaaataat aagtaaagtc ttaaaaaaaa taaatcttgt
    12901 tagccaaaaa taagatttat tataaaaaat ttaaaaacct actaaaaata atc
//
LOCUS       DAJMZY010000117        12450 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.118, whole genome shotgun sequence.
ACCESSION   DAJMZY010000117 DAJMZY010000000
VERSION     DAJMZY010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12450)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12450)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12450
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.118"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            245..1306
                     /locus_tag="OE968_003197"
     CDS             245..1306
                     /locus_tag="OE968_003197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dicarboxylate/amino acid:cation symporter"
                     /protein_id="HCP7220441.1"
                     /translation="MRDFLKNYKSSIILLACTIVGAIVGLVLGPKASILKPFGDLFIN
                     ALLMIVVPLVFLSVSSGVASIKNMERFGKIMKGTAIVFMGTTLVIAFLGITSALLFNP
                     SKGLDVSSVKNLMVTQDAETLESKGTLLDQVVSSITVKNFGDLFSSSNLLQLVIFAVL
                     IGTAIAMMGDRGNTIRKLLSEGTEAILKVVSIFMLYAPIGLGCYTATIIGELGSKIIQ
                     GYVRVFVIYSLTAAMYFLLFYSLYAFLSAGKQGFRQFWRNAIKPIATALATSSSSACI
                     PSNLEASKNIGVPDDISETVIPLGINIHKDGSVLAVIIKVAFLSGILGSGMANPATIG
                     QLFITVFVVGVFMAPVAGG"
     gene            1319..1516
                     /locus_tag="OE968_003198"
     CDS             1319..1516
                     /locus_tag="OE968_003198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:dicarboxylase symporter family
                     transporter"
                     /protein_id="HCP7220442.1"
                     /translation="MLVVSIFGFPVEAIPLLTVITTITDIPNTILNTTGNTVSSMLVS
                     RLVEGKDWLIDKTAITTKKIS"
     gene            complement(1680..2384)
                     /locus_tag="OE968_003199"
     CDS             complement(1680..2384)
                     /locus_tag="OE968_003199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HCP7220443.1"
                     /translation="MQQGSDYLKKFLEKHIDLLKKIPLFEGIKSDELEEMLECLGVVD
                     KTYTKDSIIFSVGSEVTSIGIMLKGSAHIIKEDIEGNRNIVAELLPGDLFGEVFACTR
                     LHKSNVTVTTTSSCEVLFIKFKSVTGICSSACVFHNRLVENMLQLIAEKNILLHNKIE
                     LLSRKTTREKLLMYFSKQIEQTGSHQFTIPFSRNEMADFLCVDRSSMSRELGKMRDEG
                     LLSFNKNKFEIFYFKK"
     gene            2549..3274
                     /locus_tag="OE968_003200"
     CDS             2549..3274
                     /locus_tag="OE968_003200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HCP7220444.1"
                     /translation="MMRKIIKIDEEKCNGCGLCVEACHEEAIGMVNGKAKLLRDDYCD
                     GLGDCLPTCPTNAISFEYREAAEYDEAAVKANMEAKKAQKKTLACGCPGSQSKSINRE
                     VSNSMSISNDIVEIKGSQLNQWPVQIKLVPTNASYLKNASLLIAADCTAYAYGNFHNK
                     FMKNKVTLIGCPKLDEVDYAEKLTEILKENDIKNIVVTRMEVPCCGGIVNAVKTALQN
                     SGKMIPWQIVTISVDGKIVDGEI"
     gene            3334..4926
                     /gene="hcp"
                     /locus_tag="OE968_003201"
                     /gene_synonym="priS"
     CDS             3334..4926
                     /gene="hcp"
                     /locus_tag="OE968_003201"
                     /gene_synonym="priS"
                     /EC_number="1.7.99.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxylamine reductase"
                     /protein_id="HCP7220445.1"
                     /translation="MEKMFCFQCEQTAGGKGCTINGVCGKKGGTANLQDELTGVLIGL
                     SRATIGNKNRPTSETDKIMIEGLFTTITNVSFDDEAIKRQIEKTEVEKSKLVPRCSDC
                     STTCNRNDNYDMKDLWNDNEDIRSLKSLILFGLRGMAAYAYHAMVLGYTDKDVNEFFY
                     EGLIAVGGDLSIDELLGLVMKTGEINLKCMELLDRANTETYGTPEPTQVSMKIEKGPF
                     IVVTGHDLYDLHKLLEQTKDKGINIYTHGELLPAHAYPKLKEYKHLKGNFGTAWQNQQ
                     KEFDNIPAPILFTTNCLMPVKDSYRDRVFTTEVVAYPGMVHIDEDKDFSSVIEKALEL
                     GGYREDVHMTGINGGDTLTTGFARGTVSSVQDKVVDAVKSGAIRHFLLVGGCDGAKPG
                     RNYYTEFVKQAPKDTVILTLACGKYRFNDLDLGDICGLPRLMDMGQCNDAYSAIKVAV
                     SLANAFECGVNDLPLSMVLSWYEQKAVCILLTLLHLGIKNIYIGPSLPAFLSKNVLDI
                     LVDKFALTPISTPEEDMKKILG"
     gene            5298..6203
                     /locus_tag="OE968_003202"
     CDS             5298..6203
                     /locus_tag="OE968_003202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HCP7220446.1"
                     /translation="MKNSNFNILAFDGGGLKGALSISILERIVKEYPNLLNNINMFGG
                     TSTGSLIALGLAYGVSPKEIKELYSIENSKYIFNKSYAEILRPKYENKNLKEVLLSIF
                     PEELELKDLNKLVMIPSFYIGNEENAWKPVFYNNMPNSFTKTSKVVDVAMASSAAPVF
                     FPTYNRHVDGGIIATDPSLACIIHAIDSGFKLKNTRLFSIGTGYVYNSIKADTTEWGA
                     IDWIINKEPDLPIISITLEGNSQMSQLFSQKLLGDNYYRLNPKMEKDVAMDDCDALEY
                     LMSLGENCDIKDAFGWIKKKSFYRN"
     gene            6327..7280
                     /gene="msrA"
                     /locus_tag="OE968_003203"
     CDS             6327..7280
                     /gene="msrA"
                     /locus_tag="OE968_003203"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HCP7220447.1"
                     /translation="MIKLATFAGGCFWCMVKPFDKYDGVIKVVSGYTGGHVENPTYQE
                     VCSGTTGHLEAIQITYDDDIISYDELLNIFWKQINPTDDGGQFGDRGTQYKTAIFYHD
                     EEQKNIALESREHLENSKIFDSKIVTDIIPATKFYEAEENHQDYYKKRPLNYNMYYKG
                     SGRYNFVKSHWDGNNINREELKKTLTHIQFEVTQNDMTEVPFENEYYDNNKEGIYVDI
                     VSGEVLFSSKDKFDSGCGWPSFSKPVIDKSIIERSDFSQGMYRVEVRSAKGNSHLGHV
                     FDDGPKELGGLRYCINSASLKFIPRENMEALGYGEYLKLFE"
     gene            7433..8563
                     /locus_tag="OE968_003204"
     CDS             7433..8563
                     /locus_tag="OE968_003204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCP7220448.1"
                     /translation="MNLKDFNGKRLKSARIFRAKTIEQLSKETKINKKDLKAFEENKY
                     VPNIENTLKLSNILNFPKEYFYKNENINIVVEDSHFNPQSKLPRVEEISYREKIIIIH
                     KIYSFMENYIKFPKENLPNRKVMSDININDIESLAYKTREFWDLNSTPIVNMVSLLES
                     KGIIISGMNVDRKGATIFTQKQRISKESKYLISLGNDKKSASIRNYTLACELGYIISS
                     ELRIPSKQFSEDEYACAFLLPKESFLKDLTHPEDLDYYVELKKKWIVPISAMIFRAYN
                     LEKINYKKYNYLMNEMDKKGWLIEEPLDKMKGSSPTYLKRAVELLIENKIMSVNSIVS
                     SLEEFGINLYPEDLELLMGLKKGLLSQEVNKKSKVIKFDGKK"
     gene            complement(8680..9648)
                     /locus_tag="OE968_003205"
     CDS             complement(8680..9648)
                     /locus_tag="OE968_003205"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HCP7220449.1"
                     /translation="MAIKPRKISIVGSGHVGSHCGFSLITQGVCDELFMIDIDESKSK
                     AQALDLADAVSYLPHKVHIEKGTFSDCKDSDIVVISVADSSEGPLRRQNTTRLDLLRP
                     TIGMIKSIVKPIVDSGFDGIFVVISNPVDVVTNYIWEKSGFPKNKVIGTGTALDSTRL
                     RRILSEETGIAQQSIQAYSMGEHGDSQMVPWSHVSIGGKPILDMIKDNPSTYSNLDLP
                     SIVEKNKKTGISIINGKDCTEFGIGTALVEIVKAILHNEKKVLPVSTLLEGQYNERNV
                     FAGVPCVIGKDGIEEIIEINMTEYEQNEFNKSCSVLREYIALSKTL"
     gene            9983..10171
                     /locus_tag="OE968_003206"
     CDS             9983..10171
                     /locus_tag="OE968_003206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220450.1"
                     /translation="MNYHTKEELVEALRVVSSSIINCGKGQKKFSEETSHHTRFKNII
                     EVMYISKSLIMDEISKRD"
     gene            10431..11630
                     /locus_tag="OE968_003207"
     CDS             10431..11630
                     /locus_tag="OE968_003207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanyl-tRNA editing protein AlaX-L"
                     /protein_id="HCP7220451.1"
                     /translation="MEKLYYTNQYIRDFTAEIIEIKEVENKYHVLLDKTAFFPGGGGQ
                     FGDLGKIESDDVINVYEDGKKIYHVLDKKPIKIHKVKCSIDWDRREDGMHQHFGQHVL
                     SGCFFKTFNANTTGFHLGNEYSTVDIEGNLEEDKIREIELFANEIIRQNIQVETLLPT
                     KKELKKIWLRRDLPNTDEEIRVIKIGDLDTNACCGVHPKSTGELRMIKIKKWEKHKSS
                     TRIEFLAGKRAVDEVLKRDIYLTKICRYLSCSEEDAINGIVNLNSKVEEALIKKRRLE
                     EVVSTYQVKEMIEKANKVGNISVIKKIYDDEDLKYVNKIANKIAEYENSIALLAVKFN
                     DKINLVFACSKNLKDINMGVLLKDAISLIDGKGGGSKVLAQGGGKNNGNLEATLDYAF
                     MKIEKTL"
     gene            11682..12185
                     /locus_tag="OE968_003208"
     CDS             11682..12185
                     /locus_tag="OE968_003208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCP7220452.1"
                     /translation="MEQQKDYIELYENEELIEIREARMDDLDTIAKFNYNLAKETEGK
                     ELDMDVLTKGVKALLLDERKGKYHVYTVFDKVVAQIMYTYEWSDWRNGNFLWIQSVYV
                     DKEYRRKGIFNYLFNYIKNICDKDENIVGMRLYVEKENINAKATYESLNMYECDYNMY
                     EYEVIHS"
     gene            12292..>12450
                     /locus_tag="OE968_003209"
     CDS             12292..>12450
                     /locus_tag="OE968_003209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220453.1"
                     /translation="MGVLKGMFYVFLFLDLVSIFCFFFNKGKIASNKIVFNAIGVLTF
                     VLCFMLFSY"
BASE COUNT         4851 a         1330 c         2162 g         4107 t
ORIGIN      
        1 taaaattaat ctagaaaaaa agttttaaaa gcagaatttt attaatattt atatatagat
       61 atgaactatt aataaaacgt taaaaataca aaaaaactat agaaattgac atatattcca
      121 gtatttgcta aagtagctgt tggggaaaat tacaaaaatt attaatgcgc attagataat
      181 ttactttaat ttttttagca tttggggtaa tttataatat aaagcattag aaaggaaaat
      241 ataaatgagg gactttttaa aaaattataa gtcatcaatt atacttttag catgtactat
      301 agtaggggcg atagtaggat tagtacttgg tccaaaagct tcaatactaa aaccatttgg
      361 agatttattc ataaatgctc tattaatgat agtagtacca ttagtttttc ttagtgtttc
      421 ttcaggtgtt gctagtataa aaaatatgga acgatttgga aaaataatga agggtacagc
      481 tatagtattt atgggaacaa cacttgtaat tgcattttta ggtattacat ctgcattatt
      541 atttaatccg tctaaaggat tagatgtatc aagtgtaaaa aatttaatgg tgactcaaga
      601 tgcagaaact ttagaatcaa aaggaacgtt attagaccaa gtagtatcaa gtattacagt
      661 taaaaatttt ggagatttat tttccagtag taatttacta caattagtta tatttgcagt
      721 tttaattgga acagcaatag ctatgatggg agatagggga aatacaataa gaaagctttt
      781 atcagaagga acggaagcaa tattaaaagt agtaagtata ttcatgcttt atgctcctat
      841 agggctaggc tgttatacag ctacaataat tggggaactt ggaagtaaaa taattcaagg
      901 atatgtaagg gtgtttgtaa tttattcact aacagcagcc atgtatttct tattatttta
      961 cagtctgtat gcttttttat ctgcaggaaa acaagggttt agacaattct ggagaaatgc
     1021 tataaaacca atagcaacgg cactagctac ttcttcaagt tcagcatgta taccatcaaa
     1081 tttagaagct agtaaaaata taggagttcc tgatgatata tcagaaacag ttatacctct
     1141 tggaataaat atacataaag atgggtcagt tttagcagta ataataaaag tggcattttt
     1201 atcaggtatt ttaggtagtg gaatggcaaa tccagcaacg ataggtcaat tatttataac
     1261 tgtatttgtt gttggagtat ttatggctcc tgtagcaggt ggctgactta ttggtgagat
     1321 gctcgtggtt agcatcttcg gttttccagt ggaggcaatt ccactgttaa cagttataac
     1381 tactataact gatattccta atactatatt aaatacaact ggaaatacag tatcatcaat
     1441 gttagtttca agattagtag aaggaaaaga ttggcttata gataaaacag caattactac
     1501 aaagaaaata agctaattgt acacttaatt aataaagtta ataggtatct taattttaat
     1561 aaattagata cctattaact ttttaagtaa aaatataaat ttaagattca aatatgatat
     1621 ttataatttg aatcaactaa tatagtatat attgaaataa atatgtttaa atatctattt
     1681 tattttttaa aataaaagat ttcaaattta tttttgttaa aagataacaa gccttcatct
     1741 cgcatcttgc caagctctct tgacatagaa cttctgtcaa cacataaaaa atcagccatt
     1801 tcatttcttg aaaagggaat tgtaaactgg tggctacctg tttgttctat ctgttttgaa
     1861 aaatacataa gcaatttctc gcgagttgtt ttacgagaaa gtaattctat tttattgtga
     1921 agtaaaatgt ttttttcagc tattaattgt agcatatttt caacaagcct attatgaaat
     1981 acacatgcag atgaacaaat accagttaca cttttaaact ttatgaataa aacttcgcaa
     2041 gaagatgttg tggttactgt aacattactt ttatgtagtc tagtacatgc gaatacctct
     2101 ccaaataaat ctccaggcaa gagttcagct acaatattcc tattcccttc gatatcttcc
     2161 tttattatat gagcacttcc tttaagcata attccaatag aagtaacttc acttccaaca
     2221 gagaatatta tactatcttt tgtgtaagtc ttatctacaa cacctaaaca ttccaacatt
     2281 tcttcaagtt catcactttt aattccttca aatagaggaa tttttttaag taggtctata
     2341 tgcttttcta aaaatttttt caaataatca cttccttgtt gcatatgcaa ccgataattt
     2401 gttttcattg tactatacta agtttataaa agcaagggga tataaaaatc ctactacaag
     2461 aaatttgaaa taaagaaata taggtattaa aaatatatat ataagaaatc aatactttaa
     2521 attaaaaaaa ttttatgagg tgatataaat gatgagaaaa ataattaaaa ttgatgagga
     2581 aaagtgtaat ggttgtggac tatgtgttga agcttgtcat gaagaagcta taggaatggt
     2641 aaatggaaaa gcaaaacttt taagagatga ctattgtgat gggctgggag attgtctgcc
     2701 aacttgtcca acaaatgcga tttcatttga gtatagagaa gcagcagaat atgatgaagc
     2761 tgcagtaaaa gcaaatatgg aagcaaagaa agcacaaaag aaaactttag catgtggatg
     2821 tccaggttct cagtctaagt caataaatag agaggtttca aatagtatgt ctataagcaa
     2881 tgatatagta gagataaaag gttctcaact taatcaatgg ccagtacaaa taaaattagt
     2941 accaactaat gcatcatatt taaagaatgc aagtctttta atagcagcag actgtacagc
     3001 gtatgcatat ggaaattttc ataataaatt tatgaaaaat aaggttacat taatcggatg
     3061 ccctaaactt gatgaagttg actatgctga aaaacttaca gagattttaa aagaaaatga
     3121 tattaaaaat atagtagtaa cacgtatgga agttccttgc tgtggtggta tagtaaatgc
     3181 tgttaagaca gctctacaaa atagtggaaa aatgatacca tggcaaatag ttactatatc
     3241 tgtagatgga aaaattgtag atggagaaat ttaattaagt gaattataga aaaatataat
     3301 aaattttaat aaataaaaag ggaggaataa aaaatggaaa aaatgttttg ttttcaatgt
     3361 gaacaaacag caggaggtaa aggttgtact ataaatggtg tctgtggtaa aaaggggggt
     3421 acagctaact tacaagacga acttacagga gtgttgattg gtctttcaag agcaactatt
     3481 ggaaataaga atagaccaac aagtgaaaca gataaaatta tgatagaggg gctattcact
     3541 actataacga atgtaagttt tgatgatgaa gctataaaaa gacaaattga aaaaactgag
     3601 gtagaaaaaa gtaagcttgt acctagatgt tcagattgtt caacaacttg taatagaaat
     3661 gataactatg atatgaagga tttatggaat gataatgagg acatacgttc attaaaatca
     3721 ttaatcttat ttggattaag aggtatggct gcctatgcat atcatgcaat ggtacttggt
     3781 tatacagaca aagacgtaaa tgaatttttc tatgaaggat taatagcagt tggaggagac
     3841 ttgtctattg acgaactttt aggtctagtt atgaaaactg gagaaataaa cttaaaatgt
     3901 atggaattgc ttgatagagc aaatactgaa acttatggaa caccagaacc gactcaggta
     3961 tctatgaaaa tcgagaaagg gccatttatt gtagttacag gacatgacct ttatgattta
     4021 cacaaattat tagaacaaac gaaagataag ggtataaata tatatactca tggtgagtta
     4081 ttaccagcac atgcatatcc aaaactaaaa gaatataaac atctaaaagg taattttggt
     4141 acagcatggc aaaaccagca aaaagaattt gataatattc ctgctccaat attatttaca
     4201 acaaactgtt taatgcctgt taaagatagt tatagagata gagtatttac tacagaagta
     4261 gttgcttatc caggtatggt tcatattgat gaagataaag atttttctag tgtaatagaa
     4321 aaagctcttg aacttggagg atatagagaa gatgttcata tgactggtat taatggagga
     4381 gatacattaa ctactggttt tgcaagaggt acagtttcat ctgtacaaga taaagtagta
     4441 gatgctgtaa agagtggagc tataagacac tttttattgg ttggaggttg tgatggtgca
     4501 aaacctggaa gaaattatta cactgaattt gtaaaacaag ctcctaaaga cactgttata
     4561 ttgacacttg catgtggaaa atatagattt aatgatttag accttgggga tatatgtggc
     4621 ttacctcgtt taatggatat gggacaatgt aatgatgctt atagtgcaat taaagtggca
     4681 gtttcattgg caaatgcttt tgaatgtgga gtaaatgatt tgcctcttag catggtactg
     4741 tcatggtatg agcagaaagc tgtttgtata cttcttacac tacttcattt aggtatcaaa
     4801 aatatctata tagggccttc tttgccagca ttcttatcta agaatgtatt agatatattg
     4861 gttgataaat ttgcattgac acctatatct actcctgaag aagatatgaa gaagatttta
     4921 ggataaataa acatatctat acttaaagat atttatagtt aaaatatttt taagtatgcc
     4981 acaattaaga taaggggtta aacttaaaat ttgattaaaa aatcaatttt gagatgaccc
     5041 tttatttatt ttttgtaata attgaaaaat aaacctgctt tcagtatatt ctttttaaga
     5101 atctttgtat taaatttata atacttagat atataatatc ttatatattt tattttaagt
     5161 attaaaggtt tgaatgtaac ttaaatatta aaagaggaac attgtaatat gtaacttgca
     5221 taaaatatat atactatagt gaaattattt tgattaaaat ttaaaatata aggtgtttta
     5281 tgtgggggta tatgtatatg aaaaattcta attttaatat attggcattt gatggtggtg
     5341 gattaaaagg ggcattgagt atatccatac ttgagaggat agtaaaagag tatccaaatc
     5401 tattaaacaa tataaatatg tttggaggta catctacagg gagtctaatt gcactagggc
     5461 ttgcgtatgg tgtaagccct aaagagataa aagaacttta ctcaattgaa aattcaaagt
     5521 atatttttaa taaaagttat gcagaaatac tcagaccaaa gtatgaaaac aaaaacttaa
     5581 aagaagtttt attaagtata tttccagagg aactagaatt aaaagattta aataaattag
     5641 taatgatacc aagtttttat ataggaaatg aggaaaatgc atggaaacca gtgttttata
     5701 acaatatgcc aaattctttt acaaagacta gcaaagttgt agatgtagca atggcaagta
     5761 gtgctgctcc ggtatttttt ccaacatata atcgtcatgt tgatggagga ataatagcaa
     5821 ctgacccgag tttagcgtgt ataattcatg ccattgacag tggatttaaa cttaagaata
     5881 caagactttt ttcaataggg actggatatg tatataacag tataaaggca gatactactg
     5941 aatggggagc tattgactgg ataattaata aagaacccga tttaccaatt atatctatta
     6001 ccttagaagg aaattctcaa atgagtcagt tattttctca aaaacttctt ggagataatt
     6061 actatagatt aaatcctaag atggaaaaag atgtagctat ggatgattgt gatgcattag
     6121 aatatctaat gtctttagga gaaaattgtg atataaaaga tgcttttgga tggataaaga
     6181 aaaagagctt ttatagaaat tagattcaat ttgcaattgt atttttacac atgatttcat
     6241 tgagtaggta aaaataataa aatgcagatt attaagttac ttcttaggga ataaataaag
     6301 tataatttat ttaaggagtg atgaaaatga taaaacttgc tacttttgca ggtggatgtt
     6361 tttggtgtat ggtaaaacct tttgataagt atgatggagt tattaaagta gtttctggat
     6421 atacaggtgg tcatgttgaa aaccctacat atcaagaggt atgctcagga actactggtc
     6481 atttagaagc aattcaaata acatatgatg atgatataat aagttatgat gaacttctaa
     6541 atatcttctg gaaacagatt aatcctacag atgatggtgg acaatttggt gataggggaa
     6601 ctcaatataa gactgctata ttttatcatg atgaagaaca aaaaaatata gctttagagt
     6661 caagagaaca tctggaaaat agtaaaatat ttgatagtaa aatagtgact gatataattc
     6721 cagcaactaa attctacgaa gcagaagaaa atcatcagga ttattataag aaaagaccat
     6781 taaactacaa tatgtattat aaagggtctg gaagatataa ttttgtaaaa agccattggg
     6841 atggaaacaa tataaatagg gaagagttaa aaaagacttt aactcatata caatttgaag
     6901 tcactcaaaa tgatatgaca gaagtacctt ttgaaaatga atattatgac aataacaaag
     6961 agggaattta tgttgatatt gtaagtggag aagtgttatt ttcttcaaaa gataaatttg
     7021 attctggatg tgggtggcca agtttttcaa agccagttat agataaatct atcattgaga
     7081 gaagtgattt ctcacaaggt atgtacagag ttgaagtaag aagtgctaaa ggaaattctc
     7141 atttaggtca tgtatttgat gatggtccaa aagaacttgg aggtttaaga tattgtataa
     7201 attctgcttc tcttaaattt ataccaagag aaaatatgga agctttagga tatggagaat
     7261 atttaaaact ttttgagtaa ttaggaatat ttattataaa cttatctaaa aggtgaaaat
     7321 ataaaaaaat attttcacct tttgtttttt tgtcaataat atgataaatt attaattgta
     7381 atcttattta taccaataga ttaagaattt aattttgaaa gagagaaaac aaatgaattt
     7441 aaaagacttt aatggaaaga gattaaaatc agctagaatt tttagagcaa agacgataga
     7501 acagttgtct aaagaaacta aaataaataa aaaagattta aaagcttttg aggaaaataa
     7561 gtatgtacca aatatagaaa atacattaaa attatctaat atattaaatt ttccaaaaga
     7621 gtatttttat aaaaatgaaa atataaatat cgttgtagag gatagccact ttaaccctca
     7681 atctaaacta cctagagtag aagagatttc ttatagagaa aaaataatta taatacataa
     7741 aatatattca tttatggaga attatattaa gtttccaaaa gaaaacttgc caaatagaaa
     7801 agtaatgtca gatattaata taaatgatat agaatctctt gcatataaga ctagagagtt
     7861 ttgggattta aatagtactc caatagtaaa tatggtaagt ttgttagagt ctaaagggat
     7921 tataatatca ggtatgaatg tagatagaaa aggggcaact atctttactc aaaaacagag
     7981 aattagtaaa gaatctaaat atctaatatc tctgggtaat gacaaaaagt cagcatcaat
     8041 tagaaattat actttggcat gtgagcttgg atatataata tcaagtgaat taagaatacc
     8101 aagtaagcaa ttttcagaag atgagtatgc ctgtgcattt ttattgccaa aagagagttt
     8161 tttaaaagat ttgactcatc cagaagattt agattattat gtagaactaa agaaaaaatg
     8221 gattgtacct atatctgcta tgatttttag agcatataat ctagaaaaga taaattacaa
     8281 aaaatacaat tatcttatga atgaaatgga taaaaaaggc tggttgatag aagaaccact
     8341 agacaaaatg aaaggttcaa gcccaacgta tttaaaaaga gcagttgaat tattgataga
     8401 aaataaaata atgagtgtaa atagtatagt atcaagttta gaggaatttg gaataaatct
     8461 ttatccagaa gacttagaat tattgatggg attgaaaaaa ggattgttat ctcaagaggt
     8521 aaataaaaaa agtaaagtta taaaatttga tggtaaaaaa taggtttata ttttagtatt
     8581 aaaattaaaa gcaggtacaa atgatttaaa cattaactta gttaaaagtc ttttcaataa
     8641 gtcatttacc tgcttttagt gtaagaaaga atattgaatc taaagtgttt ttgaaagtgc
     8701 aatatattcc cttaaaacag aacaagattt attaaattcg ttttgctcat attcagtcat
     8761 attgatttca ataatttctt caataccatc ttttcctata acacatggaa cacctgcaaa
     8821 tacatttctt tcgttatatt gaccttctag taatgtagaa actggaagaa cttttttctc
     8881 attgtgtagt atagctttta caatttctac taaagcagta cctataccaa attctgtaca
     8941 atctttacca tttattatac ttattcctgt ttttttattt ttttcaacta ttgatggtaa
     9001 gtctaaattg ctataagtac ttgggttgtc ttttatcatg tctaagattg gtttaccacc
     9061 aattgaaaca tgagaccaag gaaccatttg agaatctcca tgttcaccca tagaataagc
     9121 ttgaattgat tgttgagcga ttccagtttc ttcagataaa atccttctaa gtcttgttga
     9181 atctaaagct gttccagttc caatgacttt gtttttagga aagccagatt tttcccaaat
     9241 ataatttgta actacatcaa caggattaga tatgactaca aatataccat caaagccaga
     9301 atcaactatg ggttttacta tagattttat cattccaata gttggtctta gtaaatctaa
     9361 tctagttgtg ttttgtctac gtaaaggccc ttctgaagag tctgcaacac ttatcactac
     9421 tatgtcagaa tctttacagt cagaaaaagt tcctttttct atatgtactt tatgtggcag
     9481 atatgaaact gcatcagcta aatctaaagc ttgagctttt gatttagatt catctatatc
     9541 aatcataaag agttcatcac aaactccttg agttattaaa ctaaatccac aatgagaacc
     9601 aacatgccct gaacctacaa tagatatttt tcttggcttt attgccattt taaatcactc
     9661 cccctaaaat aacgatacat tgaaaattat agatgttatt aaaagctgtt tttggatatt
     9721 ttaatattct attatttcag aaaatttatt taatatgatt ttatactaaa atttttaaaa
     9781 aagcaatgtt aatatactct ctattagtga atattaaagt attatatgta tattaataat
     9841 tattaaaata tgtaatgtca ctgatagtta gaatatttaa gtgctaaaag atgtgtataa
     9901 ataataatga tgtcagttta taatgatatt aaattgagat atactgtttc tctaaattaa
     9961 aaaataaagg agtaaatgtg ttatgaatta tcatacaaaa gaagaattgg tggaagcact
    10021 gagagtagta tcttcaagta ttattaattg tggaaaagga cagaagaaat tttctgagga
    10081 gacatctcat catacacgtt ttaagaatat tatagaagta atgtatattt caaaatcatt
    10141 aataatggat gaaattagta aaagagattg aagcttattt tgcaatttaa catgttttaa
    10201 tatacatttt attatataag aaaataagta aacatacatg ttataaaata ttggaataat
    10261 atacaattat aaatttgtta acactaatat ctatatgtta aaatatagta gaagatgtta
    10321 gtaaataata ggatgagttc tattttaata caattaaatt aagcttagtt tgaaatttgt
    10381 atctaaaaag taaagtaatc tagaattaag aaaatggaga tagaattata atggaaaagt
    10441 tatattatac aaatcagtat ataagagatt ttacagcaga aataattgaa ataaaagaag
    10501 tagaaaataa gtatcatgtt ttattagata agacagcttt ttttcctggt ggaggaggtc
    10561 agtttggaga cctgggaaaa atagagagtg atgatgtaat aaatgtgtat gaagatggaa
    10621 aaaaaatata ccatgtatta gataaaaaac ctataaagat acataaggta aagtgtagta
    10681 ttgattggga tagaagagaa gatggaatgc atcaacattt tggacaacat gtattgtctg
    10741 gatgtttttt taaaactttt aatgcaaata cgacaggttt tcatttggga aatgagtata
    10801 gtacagtaga tatagaaggt aatttagaag aggataaaat tagagagata gagttgtttg
    10861 ccaatgaaat tattcgtcaa aatatacaag tagagacatt acttccaacg aaaaaagaac
    10921 taaaaaagat ttggttaaga cgtgatttgc caaatactga tgaagagata agagtaataa
    10981 aaataggtga tttagatacg aatgcatgtt gtggagtgca tccaaaatca actggtgaat
    11041 tgagaatgat aaaaataaag aaatgggaaa aacataagtc aagtacaaga atagagtttc
    11101 tagcaggtaa aagggcagtg gatgaagtat tgaagaggga tatatatttg actaaaatat
    11161 gtagatattt aagctgtagt gaggaagatg ctataaatgg tattgtaaat ctaaatagta
    11221 aagtggaaga ggctttaatt aaaaaaagaa ggcttgaaga agtagtatct acatatcagg
    11281 tcaaagaaat gattgaaaaa gcaaataagg ttggcaatat ttcggtcatt aaaaaaattt
    11341 atgatgatga agatttgaaa tatgtaaata agatagcaaa taaaattgca gaatatgaaa
    11401 atagtattgc attattagct gttaaattta atgataaaat aaatttagtt tttgcatgtt
    11461 ctaaaaattt aaaagatatt aatatgggag ttttattaaa ggatgcaata agtcttatag
    11521 atggcaaggg tggtggaagt aaagtattag ctcaaggagg aggtaagaat aatggaaatt
    11581 tagaggctac acttgattat gcatttatga agatagaaaa aactctataa atatattata
    11641 taaaaaacct tagtagataa aatagatatg gaggaataag tatggagcaa caaaaggact
    11701 acatagagtt atatgaaaat gaagaactaa tagagataag agaagcacgt atggatgatt
    11761 tggatacaat agcaaaattt aattataatt tggctaaaga aactgaagga aaagaacttg
    11821 atatggatgt tttaactaaa ggtgtaaaag cattgttatt agatgagaga aaaggaaaat
    11881 atcatgtata tacagtattt gataaagttg ttgcacagat tatgtataca tatgagtgga
    11941 gtgattggag aaatggaaat ttcctttgga ttcagagtgt atatgtagat aaggaatata
    12001 gaagaaaagg tatctttaat tatttattta attatataaa aaatatatgt gataaagatg
    12061 aaaatatagt tggaatgaga ttatatgtag aaaaagaaaa cataaatgca aaagcaacat
    12121 atgagtcttt aaatatgtat gagtgtgatt ataatatgta tgaatacgaa gtaatacatt
    12181 cgtaatataa atttgtaata ctgttatact gatgttataa agtattgatt atattgacga
    12241 ttatatgaaa taaactggat attataatta gaatttttag ggggtataaa aatgggcgtt
    12301 ttaaaaggaa tgttttatgt atttttattt ttagacttag tgtcaatatt ctgtttcttt
    12361 ttcaataaag gaaaaatagc atctaataaa attgtgttta atgcaatagg agtacttaca
    12421 tttgtacttt gttttatgct ttttagttat
//
LOCUS       DAJMZY010000118        12219 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.119, whole genome shotgun sequence.
ACCESSION   DAJMZY010000118 DAJMZY010000000
VERSION     DAJMZY010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12219)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12219)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12219
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.119"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            <1..2187
                     /locus_tag="OE968_003210"
     CDS             <1..2187
                     /locus_tag="OE968_003210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HCP7220454.1"
                     /translation="LCSLIISILVITVFNTVKLHNISNKQSKNYLNDVSTQIVMNVDS
                     KIKFILSDLRIMADFIKQYEGDSRYEYLSKRKTSYKYYDVGIIDLEGKAEFLSGKKFD
                     LKNTVSYKKGIEGKEYSEVIESMGFVLYSVPIFNDNHEVSSILIGVSNKESMNEILNI
                     DNFNGKGTIEIINSKGKPLFIGKNTELIKDLSHKYKSSGDEPWAQKMLEDFKNDKSGN
                     ITITSSKGVQCLLTYHPITRGLNDWHFLLIVPEDAVLGELNKLNSFTITMTFIITCII
                     GIITLILYIIRRKYVNQIENIAYLDSITNGINSTKFSMLVKPLISESPDSTYMMIAMN
                     IKDFKLINDCFGSEKGNMTLKHLYNILYKNIDENEEFVCRHDADLFYLLIKNRPVLEA
                     LELLYKIEADTNYFNKNRENPYFLRLSVGIYTIENHNEDLITIQDHANTARKSFNKTH
                     QSDFSFYSDIERKRLISEKEISNLMEKALENKEFFMCLQPKIDIKSGKISGAESLVRW
                     KNSEKGIIYPSDFIPLFEKSGFICKLDLYILEETCKLISKWIKEGKEVLRISVNVSRQ
                     HLNDKLFLEKYKHICNKYNVPTCLIDLELTESIFLENPEAIDIIEDIHSNGFKCSIDD
                     FGFGYSSLGILKDFKVDIIKLDRSFFVSKNNIDRGKVVIKSIIELSKRLGMKVTAEGI
                     EELEQVEFLKNVGCDYIQGYVFSKPLLISDFENFAYENNKIKNIHY"
     gene            2443..4473
                     /locus_tag="OE968_003211"
     CDS             2443..4473
                     /locus_tag="OE968_003211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HCP7220455.1"
                     /translation="MISGRMLLIMNFLKGKNKTSYKDISKQLSIEERKVRYDINNLNI
                     VLRSLNKSVIQKMNKGVLIIPDDFQVVCINNNEYVFSLTERVSIMKIISMFKIDNLNL
                     EKLSKEFQVSRSSIKNDLNVLSSELERNQITITYDKSFKISGEEDIIYKQRLNILKSY
                     SYLFGKEKSDLSVFEKYLVNVIEKIFKGIYLIDIYNWSMNLLLQMGWTLNDESFTWYV
                     SNIFLFTWYIHSDEKHPLESASLSEPCFENKFDQEFETIIQKKLTKEQIFLLKSFVFF
                     TNKYASLNEDMDLISTEIIVQDLIYNMSEILEISFKEDMILYKGLLNHIAPLIERIKQ
                     NIQIYEELLHVIPDKYQYVLEATKVSIQKNRVLSQIKNENETILLAIHFLGSIHRNER
                     NNYKNILLVCGFGYGVIAMLKDSLVNDYQINIVESIPSYKLQDYKDWESIDFIITTSK
                     IVIDLPKTIIEINPFLQEEDYLKFEEKGIKRKNVLTNYMSIKKRLDFLEEDAQKRVLS
                     IICQELGYSDERILFRQLNLSDLIGIDTIRIIDGDMKWEDAVKFSSNILANCDFVSAQ
                     YAENIIDILKNVGFYAVKDNEFALLHGNDSSLVKVSSISLLICKEAVSFGDKKVKIIF
                     CLASRDKKEQIPAIINLTKMVYKTNFIAMLESAKTKEEAEVLIHKYEKEVTV"
     gene            4470..4922
                     /locus_tag="OE968_003212"
     CDS             4470..4922
                     /locus_tag="OE968_003212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HCP7220456.1"
                     /translation="MNKLVNVKCSFKIHVNSKEEAIISLVDVVSKEGYLIDKNQFLKD
                     VLKREETLSTYIGHGIGLPHSQSVGVKNSCITIGKLDTPIEWTEEGEKVDLIFLISVT
                     KDNENNLHLKILSKLARLLMHESFRNQIRCSDEQTVYNLIKEKIEEED"
     gene            4924..5979
                     /locus_tag="OE968_003213"
     CDS             4924..5979
                     /locus_tag="OE968_003213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit EIIC"
                     /protein_id="HCP7220457.1"
                     /translation="MRILKFLQKHLMTATSYMIPFVVAGGILFALSVTLSGQAAVPET
                     GWLAKLNQIGAAGLALFIPILGGYIAFSMADKPGLAPGMIGAYLAKEVNAGFIGGIIA
                     GFIAGFVVLQLKKIKLAPTMRTLGSIFIYPLVGTLITGGIIVFLIGEPIASFMTWMTN
                     WLNGMSGVSKIPLGGILGGMIASDMGGPINKVAATFAQTQVDTLPYLMGGVGVAICIP
                     PIGLGLATLLFPKKFSKEERDSGKASLLMGCVGITEGAIPFATSDPVRVIPCIMAGSI
                     VGNIMAFLLGCLNHAPWGGLIVLPVVDNRLGYIASVLTGAVVVAVLMKLVKKDVKEDE
                     EIEEDLDESIELIFEEL"
     gene            6046..6354
                     /locus_tag="OE968_003214"
     CDS             6046..6354
                     /locus_tag="OE968_003214"
                     /EC_number="2.7.1.202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose-like transporter subunit IIB"
                     /protein_id="HCP7220458.1"
                     /translation="MKIVAVTSCPSGVAHTYMSAESLELSAKKFGIEIKVETQGSSGI
                     DNELSLKDIDEATCVILTNDVEIRNMERFKGKKVVRMSVSEIIKKSDALIKKIKDTFQ
                     "
     gene            6458..7723
                     /locus_tag="OE968_003215"
     CDS             6458..7723
                     /locus_tag="OE968_003215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II D-tagatose-bisphosphate aldolase,
                     non-catalytic subunit"
                     /protein_id="HCP7220459.1"
                     /translation="MKKLPIKTVVQRLLNLQEEGKSATLLGIGPMSPNLLQASFELAK
                     DDDFPLMFIASRNQVDADELGGGYVNGWNQETFTKDIKKVADKVGFDGLYYLCRDHGG
                     PWQRDKERNDHLPVDEAMELGKKSYLADIEAGFDLLMIDPTKDPFEIGKVIPLDVVLE
                     RTVELIEYCENERKRLNLPDIGYEVGTEETNGGLTSTETYETFITRLKVELDNRGLPM
                     PTFIVGQTGTLTRKTEQVGTFNFRNAYDLAQMAKKYGVGLKEHNGDYLDDVTLLEHIP
                     SQIIATNVAPQYGTEETRAYLKLAEVECKLEKEGLVEKTSNIRHVLLVNAIECGRWRK
                     WVVGEQKNLTTEEIFKDEVLSNEILDIAGHYTFNNDDVKKEIEVLYDNLSKNNIDGQR
                     FVVDHIKRPLRDYAECYNLKGVTTRILNK"
     gene            7811..8527
                     /locus_tag="OE968_003216"
     CDS             7811..8527
                     /locus_tag="OE968_003216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HCP7220460.1"
                     /translation="MINLIFDVDDTLYNQLTPFYTAYNKVFSSIKDISIEDLYMSSRK
                     YSDEVFHMTENGEMPIKEMHIYRIMKAFEELGNSITEKDAQSFQDEYIYQQSQITLIP
                     EVERILNFSKERNINLGIITNGPSNHQRMKLKQLNIENWVDKSNIFISSEVGFSKPDT
                     NIFRVAENVMNLDRENTYYVGDSYRNDVLGAKKAGWKSIWLNHRGHEVEELFYKPDFV
                     ILEHKDLISLFIKICSYKNM"
     gene            complement(8722..9015)
                     /locus_tag="OE968_003217"
     CDS             complement(8722..9015)
                     /locus_tag="OE968_003217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat protein"
                     /protein_id="HCP7220461.1"
                     /translation="MRNMIENLIKNNTYIDDKVIMLSMLSSAKASANMYLNSALTSST
                     PELRAIYSASLTQMVEGHTALTELSINKGWVKPYDKPIQQLTCSYKESQNVID"
     gene            complement(9021..9236)
                     /locus_tag="OE968_003218"
     CDS             complement(9021..9236)
                     /locus_tag="OE968_003218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220462.1"
                     /translation="MRILSETEKISLAAVIKMESDGLLMQRAINMLISDEDLKRQSES
                     SILATEGRIKAMQQFIVENEILISEEV"
     gene            9685..10083
                     /gene="tnpA"
                     /locus_tag="OE968_003219"
     CDS             9685..10083
                     /gene="tnpA"
                     /locus_tag="OE968_003219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011291581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HCP7220463.1"
                     /translation="MYKSNKNIVYDCKYHIVFCPKYRKPVLVGEVEKMLKEILPYKAD
                     ELGAEIIEMETDKEHVHLLISCDPQYGIHKVVKGLKGFSSRVLRENFPHLKSSMPSMW
                     TNSYFVGTVGSVSLEVVKQYIENQQVRTKK"
     gene            10080..11243
                     /locus_tag="OE968_003220"
     CDS             10080..11243
                     /locus_tag="OE968_003220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCP7220464.1"
                     /translation="MIKTHRVKLNLTRTQFELVREKQMESANCWNYIVNLSKEYYFEH
                     KQWIKKNDIQKLIKGKYNLHSQTIQAISDKFDANRKTISELRKKGNTKAKYPYKTKKF
                     YIIPFKASAINRNAKGNLKLSMSKGRYLELDFNVENIKTAEIVWRNGYYLYYTFDNEL
                     NGVVAKGTNTVGVDLGEIHSIASVTNEGVGLILSNREGRSIKQFRNKMYAYISKRLSK
                     CKKGSRQSKKLWRLKNKIRSKTDNQLMNLYHQTTRKFIDFCVEQKVCEIVLGDIKGVE
                     KDTKKKKRLNRVNRQKISQMEYGRIKDYIKYKAKEQGIEVKLVKENYTSQTCPKCSKK
                     HKPTGRTYSCTCGYETHRDIVGAWNILNKKHKYGLVDFRINHKQPINLKVSTV"
     gene            complement(11627..12139)
                     /locus_tag="OE968_003221"
     CDS             complement(11627..12139)
                     /locus_tag="OE968_003221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HCP7220465.1"
                     /translation="MLEVIKNRRSIRTYIDKNIEEDKITEILKSAMQAPSSKNAQPWE
                     FIIVDDKELLKQLSKSQHRAKHIEFAPLCIVVLGNRDKFLKPGKWIQDLGACTQNLLL
                     EVTNQGLAACWAGVFPKNKVVNKVRQTLDLPLKLVPYALISIGYSEEKNEFIDRFDEN
                     KIHRNVYKNR"
BASE COUNT         4709 a         1304 c         2080 g         4126 t
ORIGIN      
        1 ttatgttcac ttattatttc aatccttgta attactgttt ttaataccgt aaaactacac
       61 aatatatcta ataaacaatc taaaaactat ttaaatgatg tatctacaca gattgtaatg
      121 aatgttgatt ctaaaatcaa atttatttta tccgacttaa gaataatggc agattttatt
      181 aagcaatatg aaggtgatag tcgatatgag tatttatcta aaagaaagac tagttataag
      241 tattatgatg ttggaataat agatttagaa ggtaaagctg agtttttaag tggaaaaaag
      301 tttgacttaa agaatactgt ttcctataaa aaaggaattg aaggtaaaga atactcagaa
      361 gtaatagagt caatgggttt tgttctttat agtgtaccta tatttaatga taatcatgaa
      421 gtatctagta ttttaatagg tgtatccaat aaagaaagta tgaatgagat tcttaatata
      481 gataacttta atggaaaagg aactattgaa attattaata gtaagggaaa acctcttttc
      541 ataggaaaaa atactgaatt aataaaggac cttagccata aatataagag ttctggagat
      601 gaaccttggg cacaaaagat gcttgaggat tttaaaaatg ataaatcagg gaatattaca
      661 ataacctcat caaaaggtgt acaatgctta ttaacttatc atccaattac aagaggttta
      721 aatgattggc attttcttct catagtacct gaagatgctg tacttggtga acttaataaa
      781 ttaaactctt ttacaataac aatgacattt ataattacat gtattattgg aattataaca
      841 ttaattttat atattataag aagaaaatat gtaaatcaaa tagaaaatat tgcatattta
      901 gatagtataa caaatggtat aaattcaact aagtttagta tgctagtcaa acctttaatt
      961 tcagaatcac ctgatagtac ttatatgatg atagcaatga atataaaaga ttttaagcta
     1021 ataaatgatt gtttcggtag tgaaaaggga aatatgacac taaaacatct ttacaatatt
     1081 ttgtataaaa acattgatga aaatgaagag tttgtgtgcc gtcatgatgc agaccttttc
     1141 tatttgctta ttaagaatag accagtgtta gaagccctgg agttattata taaaatagaa
     1201 gctgacacaa attattttaa taaaaatagg gaaaatccat actttttaag actatcagta
     1261 ggtatttaca caattgaaaa tcataatgaa gatttaatta caatacaaga ccatgcaaat
     1321 acagcaagaa aaagctttaa taaaactcat caaagtgatt tttcttttta tagtgatata
     1381 gaaagaaaac gattaatatc tgaaaaggaa atttcaaatt taatggaaaa agcccttgaa
     1441 aataaagaat tttttatgtg cttacaacct aaaattgata taaaaagtgg aaaaattagt
     1501 ggagcagagt ctcttgtgcg ttggaaaaat tcagaaaagg gcataattta tccaagtgat
     1561 tttattcctc ttttcgaaaa aagtggattt atatgtaagt tagatttata tatactagaa
     1621 gaaacatgca aattgatttc taagtggata aaagaaggta aagaagtgtt gagaatttct
     1681 gttaatgtat cacgtcaaca tctgaatgat aaattgtttt tagaaaaata taagcatata
     1741 tgcaataaat acaatgtacc aacatgtctg atagatttag aacttactga atctattttc
     1801 ttagaaaatc cagaagctat agatataata gaggatattc attctaatgg atttaaatgt
     1861 tctatagacg attttggatt tgggtactca tcattaggga tattaaagga ttttaaagtt
     1921 gatataatta agttagaccg ttcattcttt gttagcaaaa ataatataga ccgtggtaag
     1981 gtagttatta agtctattat tgaacttagc aaaaggctag gtatgaaagt aactgctgaa
     2041 ggaattgaag aattagaaca agttgagttc ctaaaaaatg tgggatgtga ttatattcaa
     2101 ggttatgttt tttcaaaacc attattaatt tctgactttg aaaattttgc atatgaaaat
     2161 aataaaatta aaaatatcca ttattaaatg tacaagataa aaaatttagg caagttatat
     2221 aattaaaaat ataacttgcc ttttttattt atatatttaa taaaaatata tttgcagatt
     2281 ttgtaaaaat aattttcaaa tgttgtaagt tgtggctaaa gctttattgt attattctga
     2341 atatagaaag atagttactg tcttagataa aaactgaaac atacataata atataaaatt
     2401 tgctatatta ataactctaa ttattttgga aggagggaaa atatgataag tgggagaatg
     2461 ttactcatca tgaattttct aaaaggaaaa aataagacaa gttacaagga tattagcaaa
     2521 caacttagta tagaagaaag aaaagttaga tatgatataa ataatttaaa tattgttttg
     2581 cgttcattaa acaagtcagt aatacaaaag atgaacaaag gtgtgttaat tattcctgat
     2641 gacttccaag tagtatgtat aaataataac gaatatgtat tttccttaac tgagcgagta
     2701 tctattatga aaattatatc aatgtttaaa atagataatc taaacttaga aaaattaagt
     2761 aaagaatttc aggtttctag aagttcaatt aaaaatgacc ttaatgtttt gtcaagtgaa
     2821 ttagaaagaa accaaataac tattacttat gataaatctt ttaaaataag tggagaagaa
     2881 gacattatat ataagcaaag attgaacata ttaaaatcgt attcttatct ttttggtaag
     2941 gaaaaatctg atttaagtgt atttgagaag tatttagtga atgtaattga aaaaatattc
     3001 aaagggattt atttgattga tatatataat tggtctatga atttattatt gcaaatggga
     3061 tggactttaa atgatgaatc ttttacatgg tatgtgtcaa acattttcct ttttacatgg
     3121 tatatacatt cagatgaaaa acatccttta gaatctgctt cattaagtga gccgtgtttt
     3181 gaaaataagt ttgaccaaga atttgaaaca attattcaaa aaaagttgac taaggaacaa
     3241 atttttctgt taaagagttt tgtatttttt acaaataaat atgcaagttt aaacgaggat
     3301 atggatttga ttagtacaga aattatagtt caagacctaa tttacaatat gtcagaaata
     3361 ttagagatta gctttaaaga agatatgatt ctttataaag gattactcaa tcatattgcc
     3421 ccattgatag agagaatcaa gcagaatata cagatttatg aggaattact tcatgtaata
     3481 ccagataaat atcaatatgt acttgaagct actaaggttt ctattcaaaa aaacagagtt
     3541 ttaagtcaaa taaagaatga aaatgaaaca atacttttgg caatacattt cttaggaagt
     3601 atacatagaa atgagaggaa taactacaaa aatatattgt tagtttgtgg atttggatat
     3661 ggtgtaattg ctatgttaaa ggatagttta gtaaatgatt accagataaa tatagtagag
     3721 agtattccat catataagtt acaagattat aaagactggg aaagtattga cttcattata
     3781 acaacatcaa agatagtaat agacttgcct aaaacaatta ttgagataaa tccattttta
     3841 caagaagagg attatttgaa gtttgaagaa aaagggataa aaagaaagaa tgtcttaact
     3901 aattatatgt caataaaaaa aaggttggac tttttagaag aagatgccca aaaaagagta
     3961 ttaagtatta tatgtcaaga acttggatac agtgatgaga gaatattatt tagacaactt
     4021 aatttaagtg atttaatagg gattgatacc ataaggataa ttgatggaga tatgaaatgg
     4081 gaagatgctg taaaatttag ttcaaacata cttgctaatt gtgattttgt atcagcacaa
     4141 tatgctgaga atattataga tattttaaaa aatgtgggtt tttatgctgt aaaagataac
     4201 gaatttgctt tactacatgg caatgatagt tcattagtca aagtaagttc gataagttta
     4261 ttaatatgta aagaagcagt tagttttgga gataaaaagg ttaaaatcat attttgccta
     4321 gcaagcagag ataaaaaaga gcaaattcct gcaataatta atctaactaa aatggtttat
     4381 aagactaatt ttattgctat gttagaaagt gcaaagacaa aagaagaagc agaagtttta
     4441 attcataaat atgagaagga ggtcactgta tgaataaatt agttaatgta aaatgttcat
     4501 ttaaaataca tgttaattca aaagaagaag ccattatatc gttagttgat gtagtgtcaa
     4561 aagaaggata tttaatagat aaaaatcaat ttttaaaaga tgttttaaag agagaagaaa
     4621 cattgtcgac ttatattgga catggtatag gtcttcctca tagtcaaagt gtaggtgtta
     4681 aaaactcttg tattacaata ggaaagcttg atactcctat tgaatggaca gaagaaggag
     4741 aaaaagtgga tttaatattt ttgatatcag taacaaaaga caatgaaaat aatcttcatt
     4801 taaagatttt atcaaaatta gcacgtttat tgatgcatga aagttttaga aatcaaatta
     4861 gatgttcaga tgaacaaact gtttataatc ttataaaaga aaaaatagag gaggaagatt
     4921 aaaatgagaa ttttaaagtt tttgcaaaaa catcttatga cagcaacatc ttatatgatt
     4981 ccatttgtgg ttgcaggagg aatattattt gctttatcag taactttaag tggacaagct
     5041 gctgttcctg aaacaggctg gttggctaaa ctgaatcaaa ttggagctgc tggcttggct
     5101 ttattcattc ctatattagg tggatatata gcatttagta tggcagataa accaggatta
     5161 gctccaggta tgataggtgc atatttagca aaagaagtaa atgcaggttt tataggtggt
     5221 atcatagcag gatttatagc aggatttgtt gttttacaat taaagaaaat taaattagct
     5281 cctacaatga gaactttagg ttctatattt atttatcctt tagttggtac attgattaca
     5341 ggtggtataa ttgtattttt aattggagaa cctatagctt cttttatgac atggatgaca
     5401 aactggttaa atggaatgtc tggtgtttct aaaattcctt taggtggaat cttaggagga
     5461 atgatagcct cagatatggg tggccctata aataaggttg ctgctacttt tgcccaaact
     5521 caagttgaca cacttccata tttaatgggt ggagttggcg ttgcaatttg tatacctcca
     5581 attggtttag gattagctac attattgttt ccaaaaaaat ttagcaagga agaaagagat
     5641 tcaggtaaag cttcactatt aatgggatgt gttggaatta cagaaggagc tattccattt
     5701 gcaacatcag atccagttag agtaatacct tgtattatgg ctgggtcgat tgtaggaaat
     5761 attatggctt ttttattagg atgtttaaat catgcaccct ggggaggtct gatagtgtta
     5821 cctgtagttg acaataggtt ggggtatatt gcatcagtat taactggagc agtagttgtt
     5881 gcggtattaa tgaaattagt aaaaaaagac gtgaaagaag atgaagaaat tgaagaagat
     5941 ttagatgaat caattgaatt aatatttgaa gaattataaa tataaatgga aggaatttgt
     6001 ataaaaaagt aaatataaaa ctataaattt aaaggagata agaatatgaa aattgtagca
     6061 gtaacatctt gtcctagtgg agtagcacat acttacatgt cggctgaatc acttgaatta
     6121 tcagccaaaa aatttggtat agaaataaag gttgagactc aaggaagctc tggaatagat
     6181 aatgaattgt cacttaaaga tattgatgaa gcaacttgtg taatattgac taatgatgtt
     6241 gagattagaa atatggaacg ttttaaagga aagaaggtag taagaatgag tgtatctgag
     6301 ataattaaga aatctgatgc attaattaag aaaataaaag atacttttca ataaaaattg
     6361 atttatttta catataactc aaagatgttt ttaaagaaat ttttattaaa agcatctttg
     6421 aaaatatctt aaaaatagaa taaaaggaga tatagtcatg aaaaagttac caataaagac
     6481 tgtcgtgcaa agattactaa acttacaaga agaggggaaa agtgcaactc ttttaggaat
     6541 tggtcctatg tcaccaaact tgttacaagc aagttttgaa ctagcaaaag atgatgattt
     6601 tcctttaatg tttatcgcaa gtagaaatca agtagatgca gatgaactag gtggcggtta
     6661 tgtaaatggt tggaatcagg aaacttttac aaaagatatt aagaaggttg ccgacaaagt
     6721 tggatttgat ggtttatatt atttatgtag agaccatggt gggccatggc aaagagataa
     6781 agagagaaat gaccatttgc ctgttgatga agcaatggag ttaggaaaaa aatcttattt
     6841 agcggacatt gaagcaggtt ttgacctatt gatgattgac cctacaaaag acccatttga
     6901 aattggaaaa gtaattccac tagatgtagt actagaaaga actgtagaat taattgagta
     6961 ttgtgaaaac gagagaaaaa gacttaatct accagacata ggttatgagg ttggtacaga
     7021 ggaaaccaat ggaggtctga cttcaactga gacgtatgaa acatttataa ctagactaaa
     7081 ggttgaactc gataatagag gtttgccaat gccaacattt atagttggtc aaactggtac
     7141 tttaactaga aagacagaac aagtaggaac ttttaatttt agaaatgctt atgatttagc
     7201 tcaaatggct aagaaatatg gagttggttt aaaagagcat aatggcgatt acttagatga
     7261 tgtaacttta ttagaacata taccatctca aattattgct acaaatgtag ctcctcaata
     7321 tggtactgaa gaaactaggg catatttaaa attagcagaa gttgagtgta aattagaaaa
     7381 agagggctta gttgagaaaa cttctaatat cagacatgtt cttcttgtta atgcaattga
     7441 atgtggacgt tggagaaaat gggtagtagg agaacaaaaa aatctaacta ctgaagagat
     7501 atttaaggat gaagttttat ctaatgaaat actagatatt gcaggacatt atacatttaa
     7561 taatgatgat gttaaaaaag aaatagaagt gctttatgat aatttaagta agaataatat
     7621 tgatggtcaa agatttgttg tagaccatat taaacgtcct ttgcgtgatt atgcagaatg
     7681 ctataactta aaaggtgtta ctacgaggat tttaaataaa taataggact tatagtggtg
     7741 agtattgtta tactaggtat ttatagttat aattatactt accactatta aatttaggag
     7801 gactaatatt ttgattaatt taatttttga tgtagatgat actttatata atcaattaac
     7861 gcctttttac actgcatata ataaagtgtt ttcttcaata aaggatattt ctattgaaga
     7921 tttatatatg agtagtagaa agtatagtga tgaggtattt catatgactg aaaatggaga
     7981 aatgccaatc aaagaaatgc atatttatag gataatgaaa gcttttgagg agttgggaaa
     8041 ttctattaca gaaaaagatg cacaaagttt tcaagatgag tatatatatc aacaatcaca
     8101 aattacacta ataccagaag ttgagaggat tttaaatttt tctaaagaaa gaaatattaa
     8161 tctaggaatt ataactaatg gcccatcaaa ccatcaaaga atgaagttaa agcagttaaa
     8221 tattgaaaac tgggttgata aaagtaatat ttttatttct agtgaggttg gattttctaa
     8281 gccagatact aatattttta gagtagctga gaatgttatg aatttagata gagaaaatac
     8341 atattatgtg ggtgattctt atagaaatga tgtattaggt gctaaaaaag ctggttggaa
     8401 gagtatatgg ttgaaccata gaggacatga ggtagaagag ttgttttaca aacctgattt
     8461 tgtaattttg gaacataagg atttgatatc tttatttata aaaatatgta gttataaaaa
     8521 tatgtagtaa aaaaatgtta ataatagaat tgtataaaat aattaataat aactatataa
     8581 aattatatgt ttagattgtg agcaatctat tttatgttaa aaatagatta tttagaagaa
     8641 ggggaaatct taaaaaaatt tgaatatccc ctttttatta tttaattaaa atgaaatagt
     8701 tagaaatata ttttatttag tttagtcaat aacattttgg gattctttat aactacatgt
     8761 taactgttga ataggtttat catatggttt aacccatcct ttattaatac ttaattctgt
     8821 aagtgctgtg tgaccttcta ccatttgagt taatgaagct gaatatatag ctcttaattc
     8881 aggtgtacta cttgtcaatg cagaattaag atacatattg gcagatgctt tagcagatga
     8941 aagcatactt aacattatta ctttatcgtc tatataagta ttgttcttaa ttagattttc
     9001 tatcatattt ctcatgttat ctatacctcc tcagaaatta gtatttcatt ttcaactata
     9061 aattgttgca tagctttaat tcttccttct gttgctaata tactagattc tgattgtctt
     9121 tttaggtctt catctgatat taacatattt attgctcttt gcataagtaa tccgtcagac
     9181 tccattttta taactgctgc taaagatatt ttttcagttt ctgaaagtat tctcatttaa
     9241 tcatctccta tattgtaatt tatgctttaa tagtatgtct ttcttttcaa ggaaataacc
     9301 attacacttt tttacagtat tttatattct ctttatatca aaatttagtc gacctaatat
     9361 attaataata attttgtagg atatttatca ttaaatatct ataaaataaa ttatttgaat
     9421 attcataaag caaaatttat ttgtatgtac ttcttcaaga gtcaatatga gttttttcaa
     9481 aaaattaatt tttatgataa tcattaaggg ctatattttt cttaaagttg tgattatcat
     9541 tattaattta caataaaatt gccgaaaagc cctctccttt aggtgtaggg atgaaaggta
     9601 aggtcttaat ataaaaaaag ttagaataat gcttgtaatc taataccgct actgataccc
     9661 tatatttagg aggtgttagt ttttatgtat aaatctaaca aaaatatagt ttatgattgc
     9721 aaatatcata ttgtattttg ccctaagtat cgtaaacctg ttttagttgg cgaagttgaa
     9781 aagatgttaa aagaaatact accatataaa gcagatgaac ttggagcaga aataatagaa
     9841 atggaaactg ataaagaaca tgtgcactta ttaatatctt gtgaccctca atatggaatt
     9901 cataaagtag taaaaggttt aaaaggcttt agttcgagag tattaagaga gaactttcca
     9961 catttaaagt ctagtatgcc tagcatgtgg actaatagct attttgtagg tactgttggt
    10021 tctgtgagtt tagaagtagt taaacaatat atagaaaatc aacaagttag gacaaagaaa
    10081 tgataaaaac tcatagagtg aaattaaacc taactagaac acaatttgaa ttagtaaggg
    10141 aaaagcaaat ggaaagtgct aactgttgga actacatagt taacttatct aaagaatact
    10201 attttgaaca taaacaatgg attaaaaaga atgatataca aaagttaatc aaaggtaagt
    10261 acaatcttca tagtcaaact attcaagcta tatcagataa atttgatgca aatagaaaga
    10321 ctatatcaga attaagaaaa aaaggtaata ctaaagcaaa atatccatac aagactaaga
    10381 aattttatat aatacctttt aaagctagtg ctattaatag aaatgctaaa ggcaacttaa
    10441 aattatcaat gtcaaaaggc aggtatttag aattagattt taatgttgag aatataaaaa
    10501 ctgctgaaat agtatggcga aatggatatt atttatacta cacttttgac aatgaattaa
    10561 atggagttgt agccaaaggc actaataccg taggtgtaga cttaggggaa atacattcga
    10621 tagctagtgt aacaaatgaa ggtgtagggc ttattctatc taatagagaa ggcagaagta
    10681 ttaaacaatt tagaaataag atgtatgctt atatatctaa aagattaagt aaatgtaaaa
    10741 aaggtagtag acaatcaaag aagttatgga gattaaaaaa taagataaga agtaaaacag
    10801 ataatcagtt aatgaattta tatcatcaaa caactagaaa gtttatagac ttttgtgtag
    10861 agcagaaggt atgtgaaata gttcttgggg atataaaagg ggttgaaaaa gatactaaga
    10921 aaaagaaaag attaaacaga gttaatagac agaaaatatc tcaaatggag tatggtcgaa
    10981 taaaggacta tataaaatat aaagcaaaag agcaaggtat tgaagttaag ttagttaaag
    11041 aaaactacac ttctcaaact tgcccaaagt gttctaaaaa acacaaacca actggtagaa
    11101 cttatagttg tacttgtggt tatgaaactc atagagatat agttggtgct tggaatattt
    11161 taaataaaaa gcataaatat ggtttagtag attttagaat aaatcataag caaccaataa
    11221 atttaaaagt atctaccgtt tgagccatgt gtgggcgaat aactttaagg tagtagtggc
    11281 gaagacaccg tccgaagtag cttggctttg taaccacctc tgttgtactg tttaagtata
    11341 aataagtgtg ttagccacca agaatcccct tgctttagct atggggagtg tgtcaataaa
    11401 atactttaat gaaaaatagc taactttaat tgtaggatat tcttaatata tttgaaataa
    11461 ataaaaatat tgaaggatat aatattcaat tggtatataa ataataaatg atagttaaat
    11521 tttaccttag aggctaatta ggtgtttagt caaagctaat gcctttagaa tacaaatgta
    11581 ttctaaaggc atttttacta tgtattttca tttatattac taaacattat ctatttttat
    11641 atacatttct atgtatttta ttttcatcaa atcggtctat aaactcattt ttttcttcac
    11701 tatatccaat agatataagt gcataaggaa ctaattttaa tggtaagtct aaagtttgtc
    11761 taactttatt taccacttta tttttaggaa atactcctgc ccaacaagca gctagacctt
    11821 gattagtaac ttctaataat aaattttgtg tgcaagcacc taaatcttgt atccatttac
    11881 caggttttaa gaatttatct ctatttccaa gcactactat acataatggt gcaaattcta
    11941 tatgctttgc tctatgctgt gactttgaga gctgtttcag cagttcctta tcatctacta
    12001 taataaattc ccaaggttga gcattttttg atgaaggtgc ttgcatagct gattttagta
    12061 tttcagttat tttatcttct tctatatttt tatctatata tgttcttatt gaacgtctat
    12121 tttttataac ttctaacata cagattctcc tttaaataaa attatttcta tttatataat
    12181 atcattactt taaattttag ctattactta tataaagaa
//
LOCUS       DAJMZY010000119        12039 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.120, whole genome shotgun sequence.
ACCESSION   DAJMZY010000119 DAJMZY010000000
VERSION     DAJMZY010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12039)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12039)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12039
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.120"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            complement(674..1303)
                     /locus_tag="OE968_003222"
     CDS             complement(674..1303)
                     /locus_tag="OE968_003222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine amidotransferase"
                     /protein_id="HCP7220466.1"
                     /translation="MKNRKVYMYVFDTMSDWEVAYLTAELNTGRYFKKGLKPLKVITV
                     GIDKNPIITMGGLKVLPEITVDEFNMESKDLLILPGGNTWLSMNHEIILEKVKEALIQ
                     DSIVAAICGATLGLAKKGLLDVRNHTSNDLEFLKMVIPNYSGEKYYKTESVVSDENLV
                     TASGIAPLEFTFQVLKLLDVFESEALNSWLNLYKTHDSKYFFELMNCNK"
     gene            complement(1382..2344)
                     /locus_tag="OE968_003223"
     CDS             complement(1382..2344)
                     /locus_tag="OE968_003223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017561613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WYL domain-containing protein"
                     /protein_id="HCP7220467.1"
                     /translation="MAKIDNMMSILWMLNSDKKITAKQIAEKLEINIRTVYRYIDVLS
                     ASGVPIISDTGHNGGYSLLNNFTKAPLFFDIEEQKSLLHAALFAKKEGYFLDEALDKS
                     ILKLKMYSNQNQEDILTNHLRALEVIKPIGKVSIESVLKKLENSILKELSVEINYHAG
                     RKAKSKYRIINPYGIVHWNNNWYVVAFCNMRNEVRSFRVDRISEIIETSNTFNRPTEF
                     SASEFFIKGIIPEIKDEQNIIQLVVEGSIDSLDSLSQHWFLGHYLKERTPNKIIFMLE
                     EEVICKYIPNILLPYRKTIQVIEPLSLRKKIIEDLLELIDYYQI"
     gene            complement(3106..6831)
                     /gene="cbpA"
                     /locus_tag="OE968_003224"
     CDS             complement(3106..6831)
                     /gene="cbpA"
                     /locus_tag="OE968_003224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding adhesin CbpA"
                     /protein_id="HCP7220468.1"
                     /translation="MQQKCKKKALSMILSISMGLGSVASFNASNTFADTIEESTNAGN
                     AEGDTNAGNAEGDTNAGNAEGDTNAGNAGGDANAGNAGGDANAGNAGGDANAGNAGGD
                     ANAGNAGGDANAGNAEEDSNAGNAEGDANAGNAEEDANAGNAEEDSNAGNAEEDMNAL
                     VVEEATAEDPTSVGDFKISGGEINVDFKFASGVLTILSGKQMTIQNNNPNTPTTHRIV
                     IPKDVKAELIFDGVNIKTASNSPFTLTPDKDGGAYAHVILQDGSENKLESGDVYYPGM
                     RAGKGTTLTIDDSVVNRDIEGEFIVPEGGKIPRDVTLENGDKLKKGDRLTLLDSNNRG
                     SLKVVGNYYSAGIGGGNTESGGNIIINGGAITAIGQESSRNTGYGAGIGGGGNGSGGD
                     ITINGGTITAKGAYHGAGIGGGYYTTTKNALSPSVVDPSTGSGYSGNITINGGLSYSY
                     GGAHGSAFGDGCVNPGTNRGYRILVTGGTILPYMTGVGDWIFDLSATTGDVIVTGGSL
                     KATTFKSLGGAVAYGDLEKKTKVFMNKISLKYLGQDKVSTTLVDDFKMLIDGKIYPYG
                     APSYTDDQGVLYLWFSDQFKGSEVSVNLVVIDKITGGNIKPDDFYVKDIGSGSQFLKQ
                     YEEFTIDDTPPYLIIKRYDGLPFEEDVEKLFLDWILKDGGIPIITPKGEKLTDKKFMT
                     ISSQRLNEETMEPDTNLGSDDLTKQVDAGKYQLSITSTQFSNVYPFNEAYWGHRAYYK
                     AEIIPADTETSLVVEESKAKTDVFKPTDTFTLNVTISPDKKEGPDCASPRGYVQFYIN
                     GKEYKDPVELKTHNKGSESHNYSTASIEWRPLDSNHHIFTTEQTITVKYIGDDINYIE
                     GSEDEKKLKLDMTNVDVDGDGIPDINIDTDGDGRPDINIDTSGDWKPDINIDTDNTGE
                     WKPSTEGGNGDGIWKPDKNIDTNGDGNPDTDYNRPAIDTDNDGVDDYWKPDKNVDTGS
                     GGYDTGNPNLNKPDPDNGGNSKPDPDNGGNSKPDSGNGGNSKPDSGNGGNSKPDSGNG
                     GNSKPDSGNGGNSKPDPDNGGNSKPDPDNGGNGKPDPDNGGNSKPDPDNGGNSKPDPD
                     NGGNSKPDIDTDGDGKPNINIDIDGDGKPDINIDTDGDGKPDINIDIDGDGKPDINID
                     IDGDGKPDINIDIDGDGKPDINIDTDGDGKPDINIDTDGNGKPDINIDTDESLDSNVG
                     QNVQTGDQSNIMLDLALMFISLFFLIKNLTNKYLRRK"
     gene            7100..7672
                     /locus_tag="OE968_003225"
     CDS             7100..7672
                     /locus_tag="OE968_003225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class B sortase"
                     /protein_id="HCP7220469.1"
                     /translation="MEKLVKILINIICIIALTFSSLSIYIKLSEYKKADEVYTELREN
                     TINNSKHQELYDKNNDYRFWLKINNVNINYPVVQGYNNDFYLTHDFYKNYLPLGSIFM
                     DYRNNFENDKSLIVYGHYMKNKTMFGQLENYTDEVFFKENNLVEINYKVQTYTYEIFS
                     VYTADLINRDYLSIHFNNNDEFKYSLNYIT"
     gene            complement(8672..10297)
                     /locus_tag="OE968_003226"
     CDS             complement(8672..10297)
                     /locus_tag="OE968_003226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012100074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HCP7220470.1"
                     /translation="MYNVIDLFAGAGGLSLGFEMTKKFNMVAFVEKNDNAAKTYLENH
                     PSVKRYCDIKRLDFQDILNSVDKIDVVIGGPPCQGFSNANRQKRKIINGNNELVKLYV
                     DAIDKLKPNVFVMENVKTISSNKHSFYLTKKDKNHIINNLKLNIYNKDSVLYDRTEYI
                     NELFNIISIEDIESYIISNIDLKNLKIIIKKKKDICDYLNKISNYKKVKSTIEKLETR
                     GKMPKWYLELINKVKNILENMLYNRNLSDEQIFYLNLFLDIQNLFLGIYELKSESVIF
                     ENTLDDNKIIAKMDTYIIIDYINASFEYLGYVLNGSALNSIDYGVPQNRERFVLIGAK
                     KDFLKNKKIETPKPIVGENYVTVRDAIGDLAEYEASKGSMDYCFEKNSNNIEKDFYRK
                     IILDSNKIYNHVCTDTRNIALKRFEYINQGNNFHSLPDELKGTYADPERTQNTIYKRL
                     VYDKPSDTVVNVRKSMWIHPIKNRAVSAREAARLQSFPDSYKFLGTKDSVYQQIGNAV
                     PPLLGRVVAEKILNLFNDEPNEYLRDVFEALDG"
     gene            10609..>12039
                     /locus_tag="OE968_003227"
     CDS             10609..>12039
                     /locus_tag="OE968_003227"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220471.1"
                     /translation="MLTTNIHYILDNDICEIYFNKQRLTNSKYYQDNINVLNYIINEK
                     NNNLIINYNDKYIYAIYLLNIAINSYLNNTLNPNNHILTKLDKGMPLLYKGQIVIFKN
                     INNTHITLGHKNKTDTTLIPIDSAYMLITYNGHLEVNSMGKTPASKTFQTKNVLSSLG
                     FSDLKNMTGVINDSTLIILPCKDDISDLVSNIKIKDINNTYKFTELFPCSYISSTGAE
                     TDYPGNHAKQIPLLKFTTNISSAFEIIKSDKSIKNVFIIGDYPIYKHINDFERILNRK
                     RIESVNIVTSNSNISNILDLPNIDNLNIYSWSKDVLLTYSQDFENTSTFQKLWLDKLI
                     NKNICTTSVDSNISDLIHQARKSLYYISKYDFDISIKNSLMMCSYSLLKILENTPFNL
                     DFLEETIKLLNLNIATPSAKLENIKYLISSTSPDLELSALFDDVIVKFERIINELSDN
                     NTKFNTLNKLVSSYKYKTFTPNTPVIL"
BASE COUNT         4015 a         2031 c         1273 g         4720 t
ORIGIN      
        1 attagtttat ttcatctatc atctcaatca tatcatttac taactattat tctaatgagc
       61 atataacatt gaaatttata attatacaac ctaaatgcct cccaatgtac cctcaaaaac
      121 atcatttcct gtaactgaag tataattggt atattttatc actgaaataa aaaaacacta
      181 gtcaataaag actagtattt tcaagtattt tatcattctt tttttaatta ttggagacga
      241 atcatcagaa taatgcccat aatttatcta tatgcaaatt ctaaatttaa aataaagttt
      301 cagatgaatt tactattcta tgctatgata caacagaaaa aactgaaatc tatgagtggt
      361 agcttcatat aatcctagtt cctacagtaa tcaaaactga ggtttattct atatgtaact
      421 aatgataaat tttattatag gagttattag ctctatttgt gttactataa gtagtaatta
      481 tatatatgat aattttttaa cacttttctg ttggctatat agaaagtggt ttagaattta
      541 aatttaaata aaatttaaat tcaccaaaaa gaaatctata ttagaaacca ctactctatt
      601 ccaccagatt gtaatttttt gttctttata tcacaatgct ataccatatt aaattgaaaa
      661 ataaatttta aatttatttg ttacaattca ttaattcaaa aaaatatttt gagtcatgag
      721 ttttgtaaag atttagccat gaatttaatg cttctgattc aaaaacatct aaaagtttca
      781 atacttgaaa cgtaaattcc aacggagcga ttcctgaagc cgtaactaaa ttttcatcac
      841 taactacaga ttccgtttta taatattttt ctccagagta atttggtatt accattttaa
      901 gaaactctaa gtcattactt gtatgatttc taacatctaa tagccctttt ttagctaggc
      961 ctaatgtagc tccacatatg gctgcaacta tagaatcttg tattaaagct tctttaactt
     1021 tttctaatat tatctcatga ttcatggata accaagtatt tccccctggc aaaattaata
     1081 aatccttact ttccatatta aactcatcaa ctgtaatttc aggtaaaact tttaacccac
     1141 ccattgttat aataggattt ttatcaattc ctacagtaat tacttttagt ggctttaatc
     1201 cttttttaaa atatcttcct gtatttaatt cagcagttaa atatgccact tcccaatctg
     1261 acatagtatc aaatacatac atatatactt ttctattttt catctttttt actccttatg
     1321 taattaattt atatatctaa ttataaaata acttaactga catattcagt cagttaagct
     1381 attaaatttg ataataatca attaattcta gtaaatcttc aattattttc ttcctaaggc
     1441 ttagtggttc aattacttgt attgtctttc tataaggtaa aagtatattt ggtatgtact
     1501 tgcatattac ttcctcttcg agcataaata ttattttatt aggtgttctt tctttcaagt
     1561 agtgccctaa aaaccaatgt tggcttaaac tatctaaaga atctatactc ccttctacaa
     1621 ctaattgaat tatattttgt tcatctttta tttcaggtat aattcctttt ataaaaaatt
     1681 cacttgctga aaattctgtc ggtctgttaa atgtatttga tgtttctatg atttcactaa
     1741 tcctatccac tctgaaacta cgtacctcat ttctcatatt acaaaatgca actacgtacc
     1801 aattattatt ccagtgaaca attccatatg gatttataat tctatatttt gattttgctt
     1861 tacgacctgc atgatagttg atttctacag atagctcctt taatatacta ttctccaatt
     1921 ttttaagtac tgattctata gacactttcc caattggttt tattacttca agggctctta
     1981 agtggtttgt taaaatatct tcttggtttt gatttgaata catttttaac tttaatatcg
     2041 atttatctaa tgcttcgtct aagaagtatc cttctttttt agcaaataga gctgcatgaa
     2101 gtagagattt ttgctcttct atatcaaaaa aaagaggtgc tttagtaaaa ttatttaaaa
     2161 ggctataccc accattatga cctgtatctg aaattatagg tactccactc gcagaaagta
     2221 catcaatata tcggtacact gttcttatat ttatttctaa tttttcagct atctgttttg
     2281 ctgtaatttt tttgtcagag tttaacatcc acagtataga catcatattg tcaattttag
     2341 ccatgtagtt tcacctcttt ctatttgtta tataaagtta ttatataact ttttgattga
     2401 ttttttacaa aaaaacatta gtaaactgct aataatttat actaagattt atttcaaata
     2461 tttatagata gtctttttct atagttaagt tatccattaa attacatagt agtatatcca
     2521 ttttagttga tatattttca gctacctccc ttgaatatta ttacaataag tctaaatctt
     2581 ctttcttcca taaatatatt atgaggaaag actatcatct ttaatggttt aatagtataa
     2641 aagatattaa tttaaaaaaa tctattttta tatcagatgg gtattgtttt ttataaaact
     2701 gaaaaaatca cctaatagaa tctatgattt tttaacataa cctccataaa ttagtaccaa
     2761 ttatcacttc aaattcaaat ttttatctga agaatataca atcatatttc catactcaac
     2821 ataatattga gtgtttggct tgtatttaca aattattatt ctaacaaaaa caactataca
     2881 tagattaaaa tcaccttcta aacataatta ttaaaattta attaatgata tcaattccat
     2941 taatctcttt taataaaaaa ttctcttttc tatatgaaaa ttatttcaaa acttttaagt
     3001 taaatacaaa aatgactata aatagatttt tatttacaca aatctattta tagtcactat
     3061 agtttatcca ataaaataat aaaataaata tgtacacaat aaatgttatt tacgtcttaa
     3121 gtatttattt gttagatttt taattaaaaa aaacaagcta atgaacatta atgctaaatc
     3181 tagcattata ttactttgat ctcctgtttg tacattttga cctacattac tatctaaact
     3241 ttcatctgta tctatattta tatctggttt tccattccca tctgtatcta tatttatatc
     3301 cggctttcca tccccatctg tatctatatt tatatccggt tttccatctc catctatatc
     3361 tatatttata tctggttttc catctccatc tatatctata tttatatctg gttttccatc
     3421 tccatctata tctatattta tatctggttt tccatctcca tctgtatcta tatttatatc
     3481 tggttttcca tctccatcta tatctatatt tatattcggt tttccatccc catctgtatc
     3541 tatatctggt ttgctatttc ctccattatc tgggtctggt ttactatttc caccgttatc
     3601 tggatccggt ttgctatttc ctccattatc tggatctggt ttaccattgc caccgttatc
     3661 tggatctggt ttgctatttc ctccgttatc tggatccggt ttgctatttc ctccattacc
     3721 tgaatccggt ttgctatttc ctccattacc tgaatctggt ttgctatttc ctccattacc
     3781 tgaatccggt ttgctatttc ctccattacc tgaatctggt ttgctatttc ctccattatc
     3841 tggatccggc ttgctatttc ctccattatc tggatctggc ttatttagat ttggattacc
     3901 tgtatcataa cctcctgagc cagtatctac atttttatca ggcttccaat aatcatctac
     3961 tccatcatta tctgtatcta ttgctggacg attataatct gtatcagggt ttccatctcc
     4021 attggtatct atatttttat caggtttcca aataccatct ccatttccac cttctgtact
     4081 aggcttccat tcacctgtat tatcagtatc tatgttaata tctggcttcc aatcaccact
     4141 cgtatctata ttgatatctg gccttccatc accatcagtg tctatattta tatccggtat
     4201 tccatcccca tctacatcta catttgtcat atctaacttt aacttctttt catcctcact
     4261 accttcaatg taatttatat catctccaat atattttaca gtaatagttt gttcagtagt
     4321 aaaaatatga tgattgctat ctaaaggtct ccattcaata gatgcagtac tataattatg
     4381 actctcacta cccttattat gagtttttaa ttctactgga tctttatatt cctttccatt
     4441 aatatagaat tgtacgtaac ctcttggaga ggcacaatct ggtccttctt tcttatctgg
     4501 tgaaatagta acatttaatg taaacgtatc tgttggttta aaaacatcag ttttagcttt
     4561 agactcttct acaactaatg aagtttctgt atcagcagga ataatttctg ccttataata
     4621 tgctctatgc ccccaataag cttcattaaa aggatataca tttgaaaact gtgttgatgt
     4681 aatgcttaat tgatattttc cagcatcaac ttgctttgta aggtcatcac ttcctaaatt
     4741 tgtatctggt tccattgttt cctcatttaa acgttgagaa ctaatagtca taaatttttt
     4801 atctgtgagt ttttcacctt taggagtaat tattggaata cccccatctt ttaatatcca
     4861 atctaaaaat aatttttcta catcttcttc aaatggtaat ccatcatatc ttttaataat
     4921 caaatatggt ggagtatcat caatagtaaa ttcttcatat tgctttaaaa attgagaacc
     4981 tgaacctata tctttaacat aaaaatcatc tggttttata tttcctccag taattttatc
     5041 tataacaact aaattaacag atacttcaga tcccttaaat tgatcagaaa accataagta
     5101 aagaacccct tgatcatctg tataactagg tgctccataa ggataaattt ttccatcaat
     5161 tagcatttta aaatcatcaa ctaatgtagt actaacttta tcttgtccta aatactttaa
     5221 agatatttta ttcataaaaa cttttgtttt cttttctaaa tcaccgtatg caactgctcc
     5281 acctaaactt ttgaatgttg ttgcttttaa tgaaccacct gttactataa catctcctgt
     5341 tgtagcactt aggtcaaaaa tccaatctcc cactcctgtc atataaggta aaatcgttcc
     5401 tccagttaca agtatacgat atcctctatt tgttcctgga ttaacacatc catccccaaa
     5461 tgcactacca tgtgcacctc catatgaata ggaaagtcca ccattaattg taatatttcc
     5521 actataacca gaacctgtgc taggatctac tactgaggga cttaatgcat tctttgttgt
     5581 tgtatagtat cctccaccta ttccagctcc atggtatgca cctttagcag ttatagtacc
     5641 accattgatt gtgatatctc caccactacc attaccgcct ccacctattc cagctccata
     5701 tcctgtatta cgactcgatt cttgacctat agcagttata gcaccaccat taataataat
     5761 atttcctcca ctttcagtat ttccaccgcc aatacctgca gaataataat ttccaacaac
     5821 ttttaaactt cctctattat tactatctag tagtgtaagg cgatctcctt tttttaactt
     5881 gtctccattt tctagagtta catctctagg aatttttcca ccctcaggaa ctataaactc
     5941 tccttcaata tctctattta caacagaatc atcaatagtt agagtagtac cttttcctgc
     6001 tctcatacct ggataatata catcacctga ctctagcttg ttttcactac catcttgtaa
     6061 tataacatgt gcatatgcac caccatcttt atctggtgtt aaagtaaatg ggctattaga
     6121 tgcagtttta atatttactc catcaaatat taattcagct tttacatctt taggtataac
     6181 aatcctatgt gttgttggag tatttggatt attattttga attgtcattt gttttccact
     6241 aagaatagtt aaaacgccac ttgcaaattt aaaatcgaca tttatttctc caccactaat
     6301 tttaaagtct cctacagatg taggatcttc tgcagtggct tcttccacaa ctaatgcatt
     6361 catatcttct tctgcatttc ctgcattaga atcttcttct gcatttcctg cattagcatc
     6421 ttcttctgca tttcctgcat tagcatctcc ttctgcattt cctgcattag aatcttcttc
     6481 tgcatttcct gcattagcat cccctcctgc atttcctgca ttagcatccc ctcctgcatt
     6541 tcctgcatta gcatcccctc ctgcatttcc tgcattagca tcccctcctg catttcctgc
     6601 attagcatcc cctcctgcat ttcctgcatt agtatctcct tctgcatttc ctgcattagt
     6661 atctccttct gcatttcctg cattagtatc tccttctgca tttcctgcat tagtactttc
     6721 ttctatagta tctgcgaaag tatttgacgc attaaatgat gctactgatc caagtcccat
     6781 tgagatactt aaaatcattg atagtgcttt ctttttacat ttttgttgca taaattcccc
     6841 ctccccttaa taatttttaa tatacactgt atacatcctt atatacactc taataattct
     6901 taatatacac tgtatacatc cttatatgca ctctaataat ttttaatata tacttaaaac
     6961 ttatatttgt caatgaatat actgtttttt tcaaccttat atattataag tattcattat
     7021 ttgctaaata actacaataa aaattttaat tatataaaat ttatttaatt ttttatataa
     7081 taatactaag gggtaattaa ttgaaaaact agtaaaaata ttaataaata ttatttgcat
     7141 tattgcgcta actttctcta gcctttcgat ttacataaaa ttatctgaat ataaaaaagc
     7201 tgatgaagta tatacggaac tcagagaaaa cactatcaat aatagcaaac atcaagaact
     7261 ttatgataaa aataatgatt atagattctg gcttaaaata aacaacgtaa atataaacta
     7321 tcctgtagta caaggatata acaatgattt ctacctaact catgattttt ataaaaatta
     7381 tcttccttta ggtagtattt tcatggatta tagaaataat tttgaaaatg ataagagttt
     7441 aatagtctat ggtcattata tgaaaaataa aactatgttt ggtcaactag aaaactatac
     7501 tgatgaagta tttttcaaag aaaataactt agtagaaata aattataaag tacaaactta
     7561 tacttatgaa attttttcag tatatactgc tgacttaatt aacagagatt atttaagtat
     7621 acactttaat aataatgatg agtttaaata ttctttgaat tatataacct aaaaatcagt
     7681 acacaaatct gatataaagg tagatatttc agataaaatt ataactttgt atacttgtaa
     7741 ctatgaattt aaagatgctc ttactatagt tcatgctaaa ttaatttcaa aaaagagacc
     7801 tataagtagg tttgtgtaaa tgcagactta tctacagtct tttttgaacg taaaattggt
     7861 aagtatggaa taatatttat attaaacttt tgtaggcaaa gaaatgaaaa atcaaagaga
     7921 aataattatt acagatttag attaccaagc tgaattaaga aagtgtaaaa ctatggagga
     7981 tgtagttggt gaagatagta tataatagct taacttataa attatcttgg tgatattaat
     8041 gaagtttcaa agtatatatt atttattgat ataaataaaa ttaaatctgt ttctaataga
     8101 tgtacctttg tttggagaca aactattgaa gaaatataac taaaatgttg aagtagctac
     8161 ctgactttat tttgaaatgc gaacaagatt ttggcattaa gataatttag aaagaatcac
     8221 tggtacacaa ggatgtgaac ttagaatgaa tagaagtatt caggcataag gagctttcac
     8281 ccaaataaaa catagtatga actttaaaag aattctaatc aaaggcaatc aaaatattct
     8341 ttcagagttt atacctgtag tgttagccta tagtatttct aagtttcaca aataagataa
     8401 tcattaataa atgtagtatg tatattcatc ctctcaaaaa tattttttaa tcttacactt
     8461 tgtaaattat tctattttaa aattgtattt ttataccttt atttcttatg accgttttca
     8521 agctcaaatt ttgcataaat ataaattaat gaaaagcaag taaaaaaaga actgtcgcac
     8581 agcaatttaa aattactcat tcgacagtcc ttatttcgtg gattaatgtt ggataagaat
     8641 cacaagaata atacccacta ttttatttga actatccatc tagtgcttca aacacatctc
     8701 taagatactc atttggttca tcattaaata aatttaatat cttttctgct actactcgac
     8761 ctaataaagg tggtactgca tttcctatct gttgatatac agaatctttt gtacctaaaa
     8821 acttataact atcagggaat gactgcaatc tagccgcctc tcttgcgcta acagctctgt
     8881 ttttaatagg atgtatccac atagattttc ttacatttac aacagtatct gatggcttat
     8941 catatactag tcttttataa atagtatttt gagttctttc tggatcagca taagttcctt
     9001 ttaactcatc tggcaaagaa tgaaaattat ttccttgatt tatatattca aatcttttta
     9061 gtgcgatatt tcttgtatct gtacatacat gattgtatat tttattgcta tccaatatta
     9121 tctttctata aaaatctttt tcaatattat tactattttt ttcaaaacaa taatccatac
     9181 tacctttaga agcctcatat tcagctaaat cgcctattgc atctcttact gtaacataat
     9241 tttctccaac tataggctta ggagtttcta tctttttatt ttttaagaag tctttttttg
     9301 ctcctatcaa tacaaatctt tctctatttt gaggtactcc ataatcaatt gaatttagtg
     9361 cacttccatt taatacatat cctagatact caaaggatgc atttatataa tctattataa
     9421 tgtaagtatc cattttagct ataattttat tatcatcaag tgtattttcg aaaattacag
     9481 attcagattt taactcatat attcctaaaa ataaattttg aatatccaag aataagttca
     9541 aataaaatat ttgttcatct gataaatttc tattatataa catattttct aatatatttt
     9601 ttactttatt tattaattct aaataccatt ttggcatttt tccccttgtt tccaattttt
     9661 ctatggtaga ttttactttc ttataattag atattttatt taaataatca catatatcct
     9721 tttttttctt aataattatt ttcaaatttt ttaagtctat atttgatata atatatgatt
     9781 caatatcttc tatactaata atattaaata attcatttat atactcagtt ctatcatata
     9841 aaacactatc tttattataa atatttaatt ttaaattatt tattatatga tttttatctt
     9901 ttttagtcaa ataaaatgaa tgcttatttg aagatatagt tttgacattt tccattacaa
     9961 atacatttgg ctttaattta tcaatagcat caacatatag cttaactaat tcattatttc
    10021 catttataat ttttcttttt tgtctattag cattagaaaa accttgacat ggcggtcctc
    10081 ctataacaac atctatctta tcgacactgt ttaatatatc ttgaaaatct aatcttttaa
    10141 tatcacaata acgcttaaca ctcggatgat tttcaaggta tgtttttgct gcgttatcat
    10201 ttttttctac aaaagccacc atattaaatt ttttagtcat ttcaaatcct aagctcaaac
    10261 cacctgcacc tgcaaaaaga tctataacat tatacattct gacatacctc acattaactt
    10321 ttattgcagc atatcatatt ttttttcaca tgtcaatttt tgaataatca tttcaaattt
    10381 cttatacttg taatagcttt taataaattc taatattttt acttacacat tatttttctt
    10441 atttatgtct tctggataat ctattcaaat aaataacata atatattttt tatttattta
    10501 tcaatctttt tttatattat ataccatata ttatttttta gtaatataat tataatatag
    10561 aataaaaact attctaataa acaatagtaa ctactaaagg agatttaaat gttaactaca
    10621 aatatccatt atattcttga taatgatata tgtgaaattt attttaataa acaaaggcta
    10681 acaaattcta agtattatca agataatatt aatgtattaa attatattat aaatgaaaaa
    10741 aataataact taattatcaa ttataatgac aaatacatat atgctattta tttgttgaat
    10801 atagctataa actcatactt aaataataca ttaaacccaa ataatcacat tcttacaaaa
    10861 ctcgataaag gtatgcccct gctctacaag ggtcaaatag ttatatttaa aaatataaat
    10921 aatacacaca taactttagg acataaaaat aaaacggata caacacttat acctattgac
    10981 tcggcttata tgcttataac ctataatggt catttagaag tcaattctat gggcaaaact
    11041 ccagcatcta agacttttca aacaaagaat gttctatcat ctttaggttt ttcagactta
    11101 aaaaatatga ctggagtaat aaatgattct acactgatta tattgccttg taaagatgat
    11161 atatctgact tagttagtaa tattaaaata aaagatatta ataatactta taagtttact
    11221 gaactatttc catgttcata tatttcatca actggtgccg aaactgatta tcctggaaat
    11281 cacgctaagc aaataccttt acttaaattt acaactaata tttctagtgc atttgaaatt
    11341 attaaatctg ataagtctat aaaaaatgta tttataatag gtgattatcc aatttataag
    11401 catataaatg attttgaaag aattttaaat agaaaaagga tagaaagtgt aaatattgta
    11461 acctcaaatt caaatataag caatatatta gatttaccaa atatagataa tctaaatata
    11521 tactcttggt ctaaagatgt tctgttaacc tatagccaag attttgaaaa tacctctact
    11581 tttcagaaat tatggctaga taaacttata aataaaaata tatgtactac ttctgttgat
    11641 tctaatatct ctgacttgat acatcaggct agaaaatcac tttattacat atctaagtat
    11701 gattttgata tttccataaa aaactcactt atgatgtgta gttactctct tcttaaaatc
    11761 ttagaaaata caccttttaa cctagatttt ttagaagaaa ctataaagct tttaaattta
    11821 aatatagcaa ctccttcagc gaagctagaa aatataaaat atttaatttc aagtactagc
    11881 ccagatttag aattaagtgc attatttgat gatgttatag tcaaatttga aagaattata
    11941 aatgaattat ctgataataa taccaaattc aatacactaa ataaattagt atcttcatat
    12001 aaatacaaaa catttacacc aaatacacct gttatattg
//
LOCUS       DAJMZY010000120        11103 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.121, whole genome shotgun sequence.
ACCESSION   DAJMZY010000120 DAJMZY010000000
VERSION     DAJMZY010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11103)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11103)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11103
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.121"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            113..313
                     /locus_tag="OE968_003228"
     CDS             113..313
                     /locus_tag="OE968_003228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003723180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HCP7220472.1"
                     /translation="MNNGIVKWFNNEKGFGFISMESGDDVFAHFSAIQTSGFKSLEEG
                     QKVSFDIVKGARGPQAENITIL"
     gene            948..1760
                     /gene="modA"
                     /locus_tag="OE968_003229"
     CDS             948..1760
                     /gene="modA"
                     /locus_tag="OE968_003229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter substrate-binding
                     protein"
                     /protein_id="HCP7220473.1"
                     /translation="MFKKLSVLALAMIISLSITACNSKENKANDESNTKVTTADDSKE
                     KETLFVYSGAGLKKPMDEIAKKFEKENNVKVEYSYAGSAQLIAQIETSHKGDVFIVGS
                     EPIYSKAFEKELVGEHKTVAHHTPAIVVPKGNPANIQKLEDLNKDGVKLILGDKESNA
                     IGKTTQKILEKNNLKSINDNVVSTAATVNEMIVQLTSSKADATIATKDSVFGNEDVEV
                     IEIAQDKNIDQLISAGIVNYSDKKDLANKFINYIESDEAKQIFKKYGFEPVK"
     gene            1770..2561
                     /locus_tag="OE968_003230"
     CDS             1770..2561
                     /locus_tag="OE968_003230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCP7220474.1"
                     /translation="MKNKFFTTLLTGFFAIVFLFIVSPLLMLIIKGISYVPICLKSVE
                     VQYAITLSIKTSLISTIVCLLLAIPVAYFLHITKLPFKKLIIQIINLPMSLPHLVSGI
                     ALLLLFGRMGIGDSIYKIFKLDFIFTKQGIVLAQIFVNLPLTIKILHTSLNESNEKMI
                     FVARTLGCNSWEAFRFIILPNLKTGIISATVMTWSRALGEFGAVAMIAGSTRMKTEII
                     PTSIYLNMSTGDIDIAIGIAVILIFLSLTCLMLFEIFFNREVDKN"
     gene            2563..3258
                     /locus_tag="OE968_003231"
     CDS             2563..3258
                     /locus_tag="OE968_003231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCP7220475.1"
                     /translation="MLKIKNLSLDLPNFKLQENSLNINNHEYFVLLGASGSGKTLFLE
                     TLAGRYPSAKGNVSYKENLISNLPPENRNIGFVYQNFELFPNMNVEDNIRFPLKLRKI
                     PIDEQILKANHLSKLMQIEDIKNRYPKNLSGGEKQRVAFARALIAEPDILLLDEPMSS
                     LDYITKKHISKILKDVYIKYKPTVIHVTHDISEAMFFAHKIGIMNNGKINHIFDLNEE
                     IKNKGESFFYEYI"
     gene            3245..3976
                     /locus_tag="OE968_003232"
     CDS             3245..3976
                     /locus_tag="OE968_003232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220476.1"
                     /translation="MNIFDILRDYLLVQVDKYNLNMDMISIVSKSLSSKEAIGNTKRK
                     DFPIIVGKEIMLEADFKGAKGQAFTSTPSTFEGSLKDILSLDLHDNSHDRSLFIASLN
                     AVMKYLGKTDRTIHCKNNEPEVCAKKFPEFIKMEFGNPKVAIIGYQPAIIDNIKDFFE
                     TRVLDLNPEFVDTIQYNVKIEDGIRDYEDVISWADLVICTGSTLCNNSIINFLSLNKP
                     VYYYGTTIAGASNILGLKRLCFCSK"
     gene            4290..5090
                     /locus_tag="OE968_003233"
     CDS             4290..5090
                     /locus_tag="OE968_003233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HCP7220477.1"
                     /translation="MTFKNKKFTINKYKILSIILVLCLILTAFSSYVNYSHKKFKDYV
                     VFYVQHQDDEVLWAGSAIVNAIKERGKNHVFVVLVSTGCGISVFDKYKKYENLTNIQK
                     SEYRNREFLASLNSLGVIRENIILLPETNTNGNTDFNYMEKIALTFEEKFKNVTHIAH
                     TYKLDDHLQHLKNGSVIQNLYNAGKIKDAKYFVKPKFADKITFNNKIVYKAHSTEDYE
                     KVKNACQQYKIVDELEYREGIGYKSDHKSFDKLLNNKDVPAILHTPNL"
     gene            5629..6345
                     /locus_tag="OE968_003234"
     CDS             5629..6345
                     /locus_tag="OE968_003234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCP7220478.1"
                     /translation="MNQNILVVDDDREIVDAIEFYLRPDNFNVLKAYDGLEALDILIE
                     NDIKLIIMDVMMPNLDGLKTTLKIREKRNIPIILLSAKSEDMDKIIGLNMGADDYITK
                     PFNPLELTARVKSQLRRYINLGDFSNTNNSNDTNYILKSGGLELNTDTKIVSLDGEEI
                     KMTPLEYKILTLLMSRKGKIFSSHEIYENVWNEDAYSCERTIAVHIRRIREKIEINPK
                     EPKYLKVVWGIGYKIEKLNY"
     gene            6314..7903
                     /locus_tag="OE968_003235"
     CDS             6314..7903
                     /locus_tag="OE968_003235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HCP7220479.1"
                     /translation="MVTKLKNLIINDSKAKFILLLLLFLLVSILFEAVYDLNNNFSNI
                     NYYYREFALPYFYFFGTPVHLSKVELEFVCIGIILSSFLLTILCFTLYKKNKQTKVKF
                     LENVINLFSKVKIELTLILTLILLTLRFHAFTSNKMFYNTNLIIYNFIIISIVYIIYE
                     NIKYNNYNLKDMSITYVFFSNLLSMYNKKTINKKLAIVFLISIVVQAIIQYLVLIFFM
                     YIYYAEAIAIVILFTLVNTVFHFYIYNFLSVKFNYINNISKNIKNIENGNLKYKLEVI
                     GDDEISTLAKSINNITGGLETAVDANIKNERMKAELITNVSHDLKTPLTSILSYVDML
                     KNNDFDRETINDYINILDKKSQRLKLLIDDIFEASKLSSGDVEFNITKTDIRELLIQS
                     IVEFEDKIQNSSLDFIIETPEYAVFTMIDGKKTWRVFENLICNILKYSMPNTRVYIDM
                     FIKEENIILTFKNISNDKLNLKPEELIERFRRGDISRKTDGSGLGLSIAQNIIELENA
                     HMEIIIDADLFKVMLTFRKVN"
     gene            complement(8215..9717)
                     /locus_tag="OE968_003236"
     CDS             complement(8215..9717)
                     /locus_tag="OE968_003236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HCP7220480.1"
                     /translation="MGDLYKLQNGTDIRGIAYENDSKEVNLTVEEVKKIAKAFHIWLK
                     EKTKKDKVTVAIGTDSRITGSQFRSTVIETLTNDDCNVIDCEIATTPAMFMTTIMDGY
                     NSDGAIMITASHLPYYYNGLKFFTESGGLEKTDIKEMLDIAVKNDSVDYEEVNKKGEV
                     IVKNLIEDYSNLLIDKIRKGVNSSKNYEKPFSGLKILVDAGNGAGGFFAEKVLHILGA
                     DTTGSQFLNPDGMFPNHIPNPENKEAMESICKAVLDNKSDLGIIFDTDVDRAAIVGKN
                     GKPINKNALIAVISSIVLEEHPKTAIVTDSITSEGLAKFINELQGRHHRFKRGYKNVI
                     NEAIRLNSEGEECHLAIETSGHAALKENYFLDDGAYLIAKILIKVAKLSLEGKTIEEL
                     IENLEEAQEEKEVRIGINKEDFRTYAEDILKDLDSHVKSIDGWSVAPNNFEGIRVNCD
                     ESNGDGWFLLRISLHEPLLALNIESNKIGGAEQIYSKLKLFLEKYDLKGL"
     gene            complement(9827..10492)
                     /locus_tag="OE968_003237"
     CDS             complement(9827..10492)
                     /locus_tag="OE968_003237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HCP7220481.1"
                     /translation="MSIICASIMCADQMKLKEELEALEEAGVKLLHCDVMDGIFVKNL
                     AMGPELLKSISENTTIPLDIHLATETPDKYIDMMSYIKPKYISFHVESSTNVKADIQK
                     LRNYGIGPVLAISPQTSVDKIEEYISLVEGILVMTVNPGFAGQKFNLSVLDKLDKLTE
                     ILKDYDNPPFIEVDGNINKDTIKLMNGKKVDIYVVGTSALFNDKPPISYKDKIEELKE
                     SIK"
     gene            complement(10522..10968)
                     /gene="rpiB"
                     /locus_tag="OE968_003238"
     CDS             complement(10522..10968)
                     /gene="rpiB"
                     /locus_tag="OE968_003238"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose 5-phosphate isomerase B"
                     /protein_id="HCP7220482.1"
                     /translation="MKISIGCDHGGYELKEYIKENLINKGIEVEDVGTNSKESVDFPI
                     YAKKVSQNVQSKKSDLGILCCGTGIGMSIAANKFKGIRAAVVSDCFSAKATREHNNTN
                     VLCLGERVIGKGLAMRIVEEWLNSSYNGERHARRLQMIDDIEKENL"
BASE COUNT         4124 a         1509 c         1395 g         4075 t
ORIGIN      
        1 ctaaaaatta taattaaata gacatttatg ttaatctatg atacaatagt atttgtggta
       61 atacacaagt aaatcaagta tatcttgata taggttaata ggagtatttt taatgaataa
      121 tggaatagta aaatggttta ataatgaaaa aggatttgga tttatatcaa tggaaagtgg
      181 agatgacgta tttgctcatt tctcagctat acaaacttca ggatttaaat cattagaaga
      241 aggtcaaaaa gtaagctttg atatagttaa aggcgctaga ggtcctcaag cagaaaatat
      301 aactatatta taatatatag atttttcgga aagactcttt taagagtctt ttttttattt
      361 acgcattttg taaaaaagga aaaaataact tcaacaaaaa aatacttaaa aataatactt
      421 agtctaaata ctttttataa aataaatctg acaaaaatat atttataaag tatgtactta
      481 aacctacaag tactctttta attagaatat atagtaatat aataatttta gttgtggcac
      541 atcaaaattt tcaactatct cataaataca tactctttct tttgtattca attctgatat
      601 aatactttta gtaatttgtt aataaaaagc aattaaaaca tatctatatg tttcaatgtt
      661 ctattttttc actgaaatat aataaatata aaattagtta aaaagtaaaa aatctacaat
      721 aagttaattt gatttaagtt tttaaattta aaatacttta aagtattaat aaaaattaaa
      781 aataaaataa ctacctatgg aaatgacatt atgaatagat tttttcttaa ctatacataa
      841 caaaacataa caaaacatta taaaacataa caaaaactta gacatcgttt tcttagtatg
      901 atatactaaa aaagaattta cactaattta ataaggggga atatcttatg tttaaaaaac
      961 tttcagtact agctttagct atgattattt cattaagtat tactgcatgt aattctaaag
     1021 aaaacaaagc taatgatgaa tctaatacta aagtgacaac agctgatgat tcaaaagaaa
     1081 aagagactct ttttgtctat tcaggggcag gtttaaagaa accaatggat gaaatagcaa
     1141 aaaaatttga gaaagaaaat aatgtcaaag ttgaatatag ctatgcaggt tctgcacagc
     1201 taatagctca aattgagaca agtcacaaag gagacgtatt tattgttggt tctgaaccaa
     1261 tttattcaaa ggcctttgaa aaagaacttg taggtgaaca taaaacggtt gcacatcata
     1321 cacctgcaat agttgtacct aaaggaaatc cagctaatat tcaaaaattg gaagacttaa
     1381 ataaagatgg agttaaactt attttgggag acaaagagtc taatgctata ggtaagacta
     1441 cacaaaaaat acttgaaaaa aataatttaa aatctataaa tgataatgtt gtctctacag
     1501 ctgcaactgt aaatgaaatg attgtacagt taacatcaag taaagctgat gctacaatag
     1561 ccacaaaaga ttcggtcttt ggtaatgaag atgtagaagt tatagaaatt gcccaagata
     1621 aaaatataga ccaactcata tcagcaggaa tcgtaaacta tagtgataaa aaagatttag
     1681 ctaataaatt tataaattat atagagtcag acgaagctaa acagatattt aaaaaatatg
     1741 gttttgaacc tgttaagtag tgattaaact tgaaaaataa attttttact actctactta
     1801 ctggattttt tgctatagtc tttttgttta ttgtatcacc acttcttatg ttaatcatta
     1861 aagggataag ttatgttcct atatgcttaa aatcagtgga agtacagtat gcaataacac
     1921 ttagtattaa aacatcttta atatctacta tagtatgcct tttattagct attccagtag
     1981 catatttttt acatattact aaattaccat ttaaaaaact gattatacag ataataaatc
     2041 tccctatgtc tcttccacac ttagtatcag gaattgctct tttacttttg tttggaagaa
     2101 tggggattgg agattccatt tataagattt ttaagcttga ttttatattt acaaagcaag
     2161 gtatagtttt agcacaaata tttgtaaatc ttccacttac tattaaaata cttcacactt
     2221 cattaaatga aagtaatgaa aagatgatat ttgttgcacg tacccttgga tgtaatagtt
     2281 gggaagcatt tagatttata attcttccaa atctaaaaac tggaatcata tctgcaactg
     2341 taatgacttg gtcaagagca cttggtgaat ttggtgcagt agctatgata gcaggttcta
     2401 cacgtatgaa aactgaaatt attcctacat ctatatattt aaatatgtct actggtgata
     2461 tagacattgc tatcggaata gctgtaattt tgatatttct ctcacttaca tgcttgatgc
     2521 tttttgagat attttttaat agagaggttg ataagaatta atatgttaaa aataaaaaat
     2581 ttatctcttg atttacctaa ttttaaatta caagaaaata gtttaaatat taataatcat
     2641 gaatactttg ttttattagg agctagtggg tcaggtaaaa ctctatttct agaaacatta
     2701 gcaggaagat atccatctgc taaaggaaat gtatcataca aagaaaattt aatatcaaac
     2761 ttacctccag aaaatagaaa tataggattt gtatatcaaa attttgaatt atttccaaat
     2821 atgaatgttg aagataatat aaggtttcca cttaaattga gaaaaatacc tatagatgaa
     2881 cagattctta aggctaacca cttgtctaaa ttaatgcaga tagaagatat aaaaaatagg
     2941 tatcctaaaa atttaagtgg aggcgaaaag caacgagttg cttttgcacg tgccttaata
     3001 gctgaacctg atatattact tttagatgaa cctatgagtt cattggatta tattacaaaa
     3061 aaacatataa gcaaaatttt gaaggatgtc tacataaaat acaaaccaac agtgattcat
     3121 gttactcatg atatttctga agcaatgttt tttgctcata agataggaat aatgaacaat
     3181 ggaaaaataa atcatatttt tgatttaaat gaagaaataa aaaataaagg agaatctttt
     3241 ttctatgaat atatttgata ttttgagaga ttatctatta gtacaagtcg ataaatataa
     3301 tttaaatatg gatatgataa gtattgtgtc caaatctcta tcttcaaaag aagcaattgg
     3361 aaatactaag cgtaaagatt tcccaattat agttggtaaa gaaataatgc ttgaagctga
     3421 ctttaaagga gctaaaggac aagcatttac ttctactcca tctacatttg aaggttcttt
     3481 aaaagacata ttatcattag atttacatga caattctcat gatagaagtc tttttatagc
     3541 atcattaaat gcagttatga aatacttagg caagacggat agaaccattc attgtaaaaa
     3601 taacgagcca gaggtatgtg caaaaaaatt ccctgagttt ataaaaatgg aatttggtaa
     3661 tccaaaagta gcaattatag gatatcaacc agccataatt gataatatta aggacttttt
     3721 cgaaacaaga gtattagatt taaatcctga atttgtggat actattcaat ataatgttaa
     3781 gattgaagat ggtatacgag attatgaaga tgtaatatct tgggctgatt tagtgatttg
     3841 cacaggaagt acattatgta ataactcaat tataaatttt ctatcactta acaaaccagt
     3901 ttactattat ggaactacga tagctggtgc atcaaatatt ttaggtttaa aaagactctg
     3961 tttttgtagt aaataagcaa tcatatcatc aaggagtaca caaatatata tgtgtactct
     4021 ttaaatttaa aaagttatta cttttattct aagtactaaa gtaaaattct attaaaatga
     4081 atcccgaata aatgtacaat ccctttaaat ctcaattcct atcaatcatt aatattttga
     4141 ttagtcttat acataaatgt tttctttatt ttaaactaat aaaaaaattt tattccatta
     4201 atctactcta tatttttcag catttaagaa ataattttta gtactttgtt tgataatata
     4261 actaagacaa cctttcagga gatgattaaa tgacatttaa gaataaaaaa tttactataa
     4321 ataaatataa aattctatct attattctag ttttatgttt gattttaacc gcttttagta
     4381 gctatgtgaa ttatagtcat aaaaaattta aagattatgt tgtcttctat gttcagcatc
     4441 aagatgatga agtgttgtgg gctgggagtg ctattgttaa tgctataaaa gaaagaggaa
     4501 aaaatcatgt atttgtggtt ttagtatcta ctggatgtgg tatatccgtc tttgataaat
     4561 ataaaaaata tgaaaaccta acaaatatac aaaaatcaga atatagaaat agagaatttt
     4621 tagcttctct taatagcctt ggtgtaataa gggaaaatat aatattatta ccagaaacaa
     4681 atacaaatgg taatactgac ttcaattaca tggaaaaaat tgctcttaca tttgaagaaa
     4741 aatttaaaaa tgtaactcat atagcacata cttataaatt agatgaccat ttacaacatt
     4801 taaaaaatgg ttctgttatc caaaatttat ataatgctgg taaaataaaa gatgctaaat
     4861 attttgtaaa acctaaattt gctgataaaa taacttttaa taataagata gtttataaag
     4921 ctcattctac tgaggactat gaaaaggtta aaaatgcctg tcaacaatac aaaattgttg
     4981 atgaattaga atatagagaa ggtattggct ataagtctga ccataaatca tttgataagt
     5041 tattaaataa taaagatgtt cctgctatac ttcatacacc taatttataa gaaatattta
     5101 ttctttaatt taagttataa aaaggaaatt atttgagatt ttgtgatata gcactttttg
     5161 tgctatacta ctttttctca tacaactatt acccatatct aatttcatca tctcttaaaa
     5221 tatataaaga tatcatcatt aaaacctata agccttatta aatgctttat acatacctac
     5281 attaaactac ctgtttatat taaactacat taaaataaat atttgttata aattcttaat
     5341 aattatgaaa ctcatttgtt atttatattt gttaatatat gtttaaacct aaaaaattaa
     5401 taaaccaaaa taacataaga agtgtgatag attaccctag atattttcat aaacttttac
     5461 cttcagatta atatgggcgt ctatactttt aaatttacta tatgcattga caatatatta
     5521 aaagtactag tttttatttc ataatgaacg ggcttactgt tttctaatac ctctttttgg
     5581 tataaaataa aaattggtta aaaataaaat ttcaaggggg ttaataaatt gaatcaaaat
     5641 atattggttg tagatgatga tagagagata gttgatgcta tagagttcta tttgagacct
     5701 gataacttta atgttttaaa ggcatatgat ggacttgaag cattggacat actaatcgaa
     5761 aatgatatta aattaataat aatggatgta atgatgccca atttagatgg gcttaaaact
     5821 acacttaaaa taagagaaaa aaggaatata ccaataattc tcttatctgc aaaatcagaa
     5881 gatatggaca aaattatagg tcttaatatg ggtgctgatg actatataac taaaccattt
     5941 aatccactag aacttactgc tcgagtaaaa tctcaactta gaaggtatat aaatttaggt
     6001 gattttagta atacaaataa ctcaaatgat actaattata ttctaaaaag tggtggccta
     6061 gagctaaata cagatacaaa aatagtttct ttagatggtg aggaaattaa aatgacacca
     6121 cttgaatata aaatacttac acttcttatg tcacgaaaag gtaaaatttt ctcttctcat
     6181 gagatttatg aaaatgtctg gaatgaggat gcttatagtt gtgagagaac tattgctgtt
     6241 catattagaa gaattagaga aaagattgaa attaatccaa aagaaccaaa atatttaaag
     6301 gtggtgtggg gcattggtta caaaattgaa aaacttaatt attaatgatt ctaaagcaaa
     6361 atttatttta ttattattac tgtttctatt agtttctata ttatttgaag cagtttatga
     6421 tttgaataat aacttttcta atattaatta ttattataga gagtttgctc tcccttattt
     6481 ttattttttc ggtactcctg tacatttgtc aaaagtagaa ttagagtttg tctgcatagg
     6541 tattatatta tcaagttttt tattgactat actatgtttt acattgtata aaaaaaataa
     6601 acaaactaaa gtcaaattct tagagaatgt cataaacctt ttttctaagg taaaaataga
     6661 acttacactt atattaactt tgatactatt aaccttaagg tttcatgcat ttacaagtaa
     6721 taaaatgttt tacaacacta atttaataat ctacaatttt ataattatat ctatagtcta
     6781 tataatatat gaaaatatta aatataataa ctataatcta aaagatatgt ctataacata
     6841 tgtattcttt tcaaacttac ttagtatgta taataaaaaa actataaata aaaaattagc
     6901 tatagtattt ttaatatcta tagttgtaca agctattatc caatatcttg ttttgatatt
     6961 ctttatgtat atatattatg ctgaggcaat agctatagta attttattta cacttgtaaa
     7021 cacagttttt catttttata tatacaactt tttatctgtt aagtttaatt acataaataa
     7081 catatcaaaa aatataaaaa atatagaaaa tggcaattta aagtataaat tagaagttat
     7141 aggagatgat gaaatatcta ctttagccaa aagtataaat aatataacag gcggtcttga
     7201 aactgctgta gatgctaata taaaaaatga aaggatgaag gcagagctta tcacaaacgt
     7261 atctcatgac ttaaaaactc cacttacatc tatattaagc tatgttgata tgttaaaaaa
     7321 taatgacttt gacagagaga ctataaatga ctatataaat attttagata aaaaatcaca
     7381 aagattaaaa ttattaatag atgacatatt tgaagcatct aagctaagta gtggagatgt
     7441 agaatttaat ataacaaaaa ccgatataag agaactttta attcaaagta ttgtagaatt
     7501 tgaagacaaa attcaaaata gcagtttaga ttttataata gaaacacctg aatatgctgt
     7561 ttttaccatg atagatggta aaaaaacttg gagagttttt gagaatctaa tttgcaatat
     7621 actaaaatac tctatgccta acactagggt ctatatagat atgtttataa aggaagaaaa
     7681 tataatatta acgtttaaaa atatttcaaa tgataaacta aatctaaaac cagaagagtt
     7741 aatagaaaga tttagaaggg gtgatatatc tagaaaaaca gatggctctg gtcttggttt
     7801 atcaattgct caaaatataa ttgaattaga aaatgcacac atggaaataa ttatagatgc
     7861 tgatttattt aaggtaatgc ttacttttag aaaagttaat tgatatatta atataaaaat
     7921 atattttaag ttatttaaac aagaaaaaaa cctccttaga ggtctttttc taaatgttgg
     7981 ggtttatatt tacatatttt ttgattatac ctttttggtg tgatattaat acattttaaa
     8041 ttatatttct ctataattca tcacatattt catctctctg tatctataat atcacatagt
     8101 gtttccataa tcagttacat ctctgttacc taagattaca attttgtaat atttgtaatc
     8161 ttaggtacaa atttacattt attcttcaat ataaatatat tctttctatt taccctaaag
     8221 accttttaaa tcatattttt ctaagaaaag ttttaactta gaataaattt gttctgctcc
     8281 gccaatttta tttgattcaa tatttaaagc taataatggt tcatgtagtg atattctaag
     8341 taaaaaccat ccatctccat ttgattcatc acaattaact cttatgcctt caaaattatt
     8401 tggtgctaca gaccatccat caatactctt aacatgagaa tctaaatctt ttaatatatc
     8461 ctctgcatat gttctaaaat cttctttatt aatgcctatt ctaacttctt tctcttcttg
     8521 agcttcttca aggttttcta tcaattcttc tatagtcttt ccttccaagg atagctttgc
     8581 tacttttatt aaaattttag ctattaaata tgccccatca tctaagaaat aattttcttt
     8641 taaagcagca tgtccagacg tttctatagc taaatggcac tcttcacctt cactatttaa
     8701 tcttatagct tcatttatta catttttata tcctctttta aatctatgat gtcttccttg
     8761 taattcattt ataaatttag caagtccttc agaagtaatc gaatctgtta ctatagctgt
     8821 ttttggatgt tcttctaata ctattgatga tataacagct ataagagcat ttttatttat
     8881 tggtttgcca tttttaccta caatagcagc tctgtctaca tctgtatcaa agattattcc
     8941 taggtcgctc ttattatcca acacagcttt acatatgctt tccattgctt ctttgttttc
     9001 gggattaggt atatgatttg ggaacatacc atctgggttc aaaaactgac tacctgtcgt
     9061 atctgctccc agtatgtgta aaactttttc agcaaagaat ccaccagccc catttcctgc
     9121 atcaaccaat atcttaagcc cagaaaaagg cttttcataa tttttacttg aatttacacc
     9181 ttttctaatt ttatctatca ataaattaga ataatcttct attaaatttt ttactataac
     9241 ttcacctttt ttatttactt cctcatagtc tacactatca tttttaacag ctatatccaa
     9301 catctctttt atatcagttt tttctaaacc tccactttct gtgaaaaact ttaaaccatt
     9361 atagtaataa ggtaagtgac ttgctgtaat cataatcgcc ccatcagaat tgtatccatc
     9421 cataatagtt gtcataaaca tagctggagt tgtggcaatc tcacaatcaa ttacattaca
     9481 atcatcatta gttaaagttt caataacagt acttctaaat tggcttcctg ttatcctaga
     9541 atcagttcct atggcaacag ttactttatc tttcttagtc ttttctttta accaaatatg
     9601 aaacgcttta gctatttttt ttacttcttc tacagttagg ttaacttctt tagaatcatt
     9661 ttcatacgct attcctctaa tatcagtacc attttgtagt ttatataggt ctcccataaa
     9721 aaattctcct tactcaacca aaatttttat taaatattat aaaatttctt gtttccacct
     9781 aaatttttac tattaaacag aaacatatta taattttatt acatggttac tttatacttt
     9841 cttttagttc ttctatttta tctttatatg aaattggagg cttatcatta aataaagctg
     9901 aagtaccaac aacatatata tctacttttt taccattcat aagtttaata gtatccttat
     9961 ttatatttcc atcaacctct ataaatggag gattatcata atcttttagt atctctgtaa
    10021 gtttatccaa cttatccaat acagaaagat taaacttttg acctgcaaac cctggattta
    10081 ctgtcattac taagataccc tcaactaaac ttatatattc ttctatttta tccacacttg
    10141 tttgagggct tattgctaac actggcccta taccataatt tcttaacttt tgtatatcag
    10201 cttttacatt tgtacttgat tctacatgaa aagaaatata ttttggcttt atataagaca
    10261 tcatatcaat atatttatct ggagtttctg tggctaagtg tatgtctaaa ggtattgttg
    10321 tattttcact tattgatttt aataactctg gtcccatagc caagttttta acaaatattc
    10381 catccataac atcacaatga agtaatttta cacctgcttc ttcaagagct tctaattcct
    10441 cttttaactt catttggtct gcacacatta ttgaagcaca aataatagac ataacgctcc
    10501 cccttgttgt aaattatata tttataaatt ttctttttct atatcatcaa tcatttgtaa
    10561 tcttcttgca tgtctttctc cattataact tgaatttaac cattcttcaa caattctcat
    10621 tgctaatcct ttcccaataa ctctttctcc taaacaaagt acatttgtat tattgtgttc
    10681 tctagttgcc ttagctgaaa aacagtcaga aacaacagct gctctgattc ctttaaactt
    10741 atttgctgca atagacatac ctattcctgt tccacaacaa agtatgccta aatcagattt
    10801 tttactttga acattttgac ttaccttttt tgcatatatt ggaaaatcta cactttcttt
    10861 tgaatttgta cccacatctt caacttctat acctttattt attaaatttt cctttatata
    10921 ttcctttaat tcataaccac catggtcaca tccaatagat attttcatta aatagcacct
    10981 ctttttataa tttttttgat tactttcaga ctattttata attatcataa aaataaagta
    11041 ttgtaaaaat aaagctgtcc cattgtagaa atttctttct atttttaaga cagctttaat
    11101 tga
//
LOCUS       DAJMZY010000121        10693 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.123, whole genome shotgun sequence.
ACCESSION   DAJMZY010000121 DAJMZY010000000
VERSION     DAJMZY010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10693)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10693)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10693
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.123"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            163..1323
                     /locus_tag="OE968_003239"
     CDS             163..1323
                     /locus_tag="OE968_003239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF819 family protein"
                     /protein_id="HCP7220483.1"
                     /translation="MIETGFVYCSFLVVFVGVIFFMVDKLKWKVFDVINPMLLIYLGS
                     AILGSFGLFAQNEDVGTYQNIITVNFLPLMLVFLLIQCDLRKILKMGPKMLLSFFCAT
                     FTFMLGFVIAFIIFKNSMGADSWKILGAASGSWIGGSSNMIAAANALGVAEEGLSYAI
                     LMGSIGYTVWMSVCLMSVKFGPKFNKWTKCDTSFIDEVTSKLEKENKDNTAPTFVELM
                     ILLSVGFGVASFAQIVSKILPTSGILNETMWVVLVASTVSILLGMTKISKLKGSTLVG
                     NVFMYLLLAATGSKANFFGLSEAPVYIMFGLVVVLVHAISFIGLAKLFKLDLFTCEVG
                     SIANIGGVTTAPMIAGVHNPVLIPVGVLMGLLGNIIGTYCALMVTQILHMLA"
     gene            1666..1827
                     /locus_tag="OE968_003240"
     CDS             1666..1827
                     /locus_tag="OE968_003240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220484.1"
                     /translation="MIIPSRRIQDITLTNLKNGEVTLIELDEIYKKMGFLFVVSEGKL
                     KKIKKENHH"
     gene            2020..2649
                     /locus_tag="OE968_003241"
     CDS             2020..2649
                     /locus_tag="OE968_003241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HCP7220485.1"
                     /translation="MKIVTYNIHKGMDSNNRLTLTKMGLYLKQLDCDVICLQEVLYPQ
                     FLALKAVLNMGGVFATNVKKVNMIYGICTFTTSKMLNSNHFFLTSKKEQRGALCITID
                     AYGRIINVINTHLGLDRQERAKQLDEIIDYRNRLVGIVILCGDFNEKNVFLSMFNDMA
                     ISLNKSYLPTFEKSNSRIDYIFVNKNTELKGYTVEKIYLSDHYPVIGYI"
     gene            2889..4148
                     /locus_tag="OE968_003242"
     CDS             2889..4148
                     /locus_tag="OE968_003242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanW family protein"
                     /protein_id="HCP7220486.1"
                     /translation="MGRRTTRVSRLGKEKKRSVLIVLAALVLIMGGFTYFFNSKFLYN
                     GKIAKNVYIEGVNVSDMTKAEALKAITDKYTPEDLNLAYDGKKYTISPKDIDLKYDTE
                     DVVKDAYESTKKGSYFQNLKKYIDIRVNKANMKIKAEYDEAKLSSKVSSIADSINVKM
                     KNASISVGSGGLSYTDSVVGREFDLAANKESIYNMIKNKEHKTLELKVNLQKPDITTE
                     QVKTVNSVIGQYSTTYSQAVEGRSYNVGLSARKTSDVLLMPGEEFSYNKLTGPSNKAN
                     GYKDAPVIVYGKLEQSAGGGVCQTSSTVYNAALLSGMEITQVTNHSSASTYVPKGRDA
                     TVSDGGLNLKFKNPYKHPVYIKNYAGGGSVSSVIYGNSGDKPNISIEVKQTGQNKYST
                     YRIFKDSSGKVIKKEHISNSSYKELKK"
     gene            4407..5402
                     /locus_tag="OE968_003243"
     CDS             4407..5402
                     /locus_tag="OE968_003243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein kinase"
                     /protein_id="HCP7220487.1"
                     /translation="MYEEVTWLNFIGNRYEVVNSDDVLEINKIYKARDVFYRKNVLIK
                     VIKHNNYICEDFVSNLIDESTALDEINSPYILKIIDVGIHCTEETTLYYVVSEDFNGI
                     GLDELILGNYLHLEAIVNIMIQVLKALEMIHRNHSYHGSLKSSSIIVDTEYNIKICDF
                     GITKANNGVNTRSYGNRRYLCPHQLCINYTDKESDFFATGLILFESIFKKLPFGESNS
                     EEKMLQSIDKGLDWNSIKAINGNTELINVIKRLLGRNNKYTRANDIIIDLSKVMYEKA
                     YIEVEDEKEEEQKQDKVIQVKKEYKSKMRKKLHKKLVVAGLAIVMISMIIISSII"
     gene            5648..6715
                     /locus_tag="OE968_003244"
     CDS             5648..6715
                     /locus_tag="OE968_003244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA ligase RtcB family protein"
                     /protein_id="HCP7220488.1"
                     /translation="MSNIKIIASNKCWIEDIARKQLEDISKLNGILRVVGLPDLHAGK
                     IPVGLAVETKNIIYPHIIGNDIGCGMTLFKTGVLKKKFKKDKWIKSLSKIKDLSDIEI
                     KNTYKEECPILNLGTIGSGNHFVEIQCISEIYNKEQFEQLKFSSDDIMMLVHCGSRNY
                     GEDILKKFYDKDGLEVESEKAIDYIKKHDNALMWAERNREAISKKIMQSIGTSGDVET
                     IFSINHNFIEKREDKFIHRKGAVSSERGAVIIPGSRGSLSYIVMPTENTEISLYSLSH
                     GAGRKWSRSVCKSRLKSKYNKDTIKQTKFKSQIICNDVNLLFQEAPEAYKNIEQIIES
                     LIEYELIQVVATMKPLITYKG"
     gene            7249..9159
                     /locus_tag="OE968_003245"
     CDS             7249..9159
                     /locus_tag="OE968_003245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HCP7220489.1"
                     /translation="MNSNTFERLQLNEVKELIKIHCVSSLGKNLIDKLTPSGNIGVVR
                     RKLAENKEARKIIENSNHIPLEGLFNAGSTIDKIEKGMIIEPVELVNIEDFLRGCRKM
                     KAFMLEKEFYSPTLSSYALNITECKSIEDEINYCIKSNKVDSNASKELKKIRRNIEIT
                     EGKIKDRLNKFITSTVNKKYIQEFIISKRNDRYVIPIKSSYKNEVNGTILDTSSKGNT
                     VFIEPISVSNLSTELTMLKADETIEEYKILSYLTELIFEKISQIKLNIEILSEYDMVF
                     AKAKYSQKIKGITPKINNNGYIKIIKGKHPLLTGDAVPLDFEIGKNYRSLIITGPNAG
                     GKTVTLKTVGLLTLMVQCGFDISAKEGSEFSVFEKVFVDIGDNQSIENALSTFSSHIK
                     NIAEIMSLSNNSTLVLFDEIGSGTEPNEGAGLAISLLEEFYKMGCITIASTHYGEIKK
                     FATLHPEFENAGMMFDKETLEPLYKLTIGKSEDSNALFISKKMGIKNRVLDRAKEYVI
                     DRNYNLDLVKRSKLQSNIEDKNSSEVILNYTDYNVGDKVKLLDEDDFGIVYKPMDKFN
                     NVEVLFNDNFISVNIKRLQLSIKASELYPEGYDLDVLFTSFKERKLEKDIQRGSKKAL
                     KKIQKEIRENRK"
     gene            complement(9222..9845)
                     /gene="ytaF"
                     /locus_tag="OE968_003246"
     CDS             complement(9222..9845)
                     /gene="ytaF"
                     /locus_tag="OE968_003246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation membrane protein YtaF"
                     /protein_id="HCP7220490.1"
                     /translation="MIESILLVTSLCIDAFVTSFGYGVNKVKVPLYSNIIISVVCSAI
                     LAISLFAGTIVRDFLPQNITMLICFFILFLLGSARLIESFFKSYFKKKSIHSKNYNFN
                     MLDLKLNFNVSIEPDVLDTSKSKVLKSAEAFTLALALSLDGLAIGFGSGLVGVNYIQV
                     ILFSLISNIIAVLLGCLLGNMFVKNVNLNLSWLSGLILLVIGFMKIC"
     gene            10033..10677
                     /locus_tag="OE968_003247"
     CDS             10033..10677
                     /locus_tag="OE968_003247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCP7220491.1"
                     /translation="MEQHSKVGNFGDLLKVLLDEKELSMGELSKKSGIDKSTISRIAN
                     NKQKPNINHLEKMAIHLNINLEELLKASGYEFRNSNNQIFNADSDFSNFDDILGFANL
                     INDKNFNGNIEKELSKCKLYVQTDEGKKLLFDNFNKKIDSIEKQGQFTDRLRQMYADF
                     CTDGLTIKKYLLIGSMLLYFVISTDVIPDFVFPIGFMDDLVALNIVTKLLKNDK"
BASE COUNT         4370 a         1056 c         1757 g         3510 t
ORIGIN      
        1 tgtgcaaatc tttattaata tatgtcaata gttaggtata tatgtattta attagcatga
       61 tatagataaa agtatttatt ttaattgtct attatctgaa aaagtcttta cttagaaatc
      121 ataaaaatca aattaattag gaaaagaaag ggtgtgtata atgtgattga gactggattt
      181 gtatattgta gtttcttggt tgtattcgta ggtgtaattt tttttatggt tgataaattg
      241 aaatggaagg tatttgatgt tattaatcca atgcttttaa tatacttagg ttcagctata
      301 cttggatcat ttggtttatt tgcacagaat gaagatgttg gaacgtatca aaacataata
      361 acagtgaact tccttccatt aatgttagtg tttttgttaa ttcaatgtga tttaagaaaa
      421 atattaaaga tggggcctaa aatgttatta tcatttttct gtgctacatt tacatttatg
      481 cttggatttg ttatagcatt cataattttt aaaaattcaa tgggtgcaga ttcatggaaa
      541 attcttgggg cagcatctgg ttcatggata ggtggctcat caaatatgat tgcagcagct
      601 aatgctctag gagttgcaga agaaggactt agttatgcaa tacttatggg ttctatagga
      661 tatacagtat ggatgtctgt ttgtctaatg tctgtgaaat ttggacctaa atttaacaaa
      721 tggacaaagt gcgatacaag ttttatagat gaggttacat caaaacttga aaaagaaaat
      781 aaagataata cagcacctac gtttgtagaa cttatgattt tactttctgt tgggtttgga
      841 gttgcgtctt ttgcacaaat tgtatccaag atacttccaa cttcaggtat acttaatgaa
      901 actatgtggg tagtacttgt tgcatctaca gtatcaatat tattgggtat gacaaaaata
      961 tcaaagctta aagggagtac actggtagga aatgtgttta tgtatttact ccttgcagct
     1021 acaggtagta aagcaaattt ctttggattg tcagaagcac ctgtttacat aatgtttgga
     1081 ttggtagtag tccttgtaca tgctatttca tttatagggc ttgctaaact atttaaactt
     1141 gatttattta cttgtgaagt aggaagtata gctaatatag gaggagtaac tacagctcca
     1201 atgattgctg gggttcacaa tcctgtatta ataccagtag gtgtacttat ggggcttcta
     1261 ggaaatatta tagggactta ttgtgctctt atggtaactc aaatattaca tatgttagct
     1321 taatgaaaat atggtataaa attaataatt taaataagaa aagtcatttc aatttaagca
     1381 gaagctttta ctgaaatggc tttttttgtt tgacaagata atctatttca agaagatgtt
     1441 ttgacatatt tagtgtataa tattgtaaaa tttactaaaa acgagatata tttaattttt
     1501 atattgaatc gaacgtctgt atgatgtata ataaatatac agaacgaatg tttgcggaac
     1561 gggtgttttt tgaatttatt ttaataattt atgaatatat atcagaatgc ataaatatat
     1621 ttaaatataa agattaaaaa gaatttaaag gagtgttgat aacttatgat aattccatca
     1681 agaagaatac aagatataac attaacaaat ttaaaaaatg gtgaagtaac tttaattgaa
     1741 ttggatgaaa tatacaagaa gatgggattt ttatttgttg ttagtgaagg caaattgaaa
     1801 aagataaaaa aggagaatca tcattagaaa tgaatgaaat aataaatatt ataatagttt
     1861 ataaaaccta acttatgtag aatataaata cttaagttag gtttttttgt gataaagttt
     1921 ataagtactc aattttataa gataaataat ggttttaagt gaaaagtaaa taagtttaaa
     1981 ttttagtaag tattatattg cataagaggt gatattatta tgaaaatagt aacctacaat
     2041 attcataaag gtatggattc aaataataga ttaactctaa ctaaaatggg gttatattta
     2101 aaacaattgg attgtgatgt aatttgtttg caagaagtat tatatcctca atttttagct
     2161 ttaaaagctg ttttaaatat gggtggtgtc tttgctacaa atgtaaaaaa agtaaatatg
     2221 atatatggta tttgtacatt tacaacatct aaaatgttaa acagtaatca ttttttctta
     2281 actagcaaaa aagaacaacg gggagctctt tgtataacta tagatgcata tggaagaatt
     2341 ataaatgtaa taaatactca cttgggactt gataggcagg agagagcaaa acaattagac
     2401 gaaataatag actataggaa cagattagtg gggatagtta ttttatgtgg tgattttaat
     2461 gagaaaaatg tctttttaag tatgtttaat gatatggcta tttcactaaa caagtcttac
     2521 ttaccaacat ttgaaaaatc aaactctaga atagattaca tttttgttaa taaaaatact
     2581 gaactaaaag gatacacagt agaaaaaatt tacctgtcag accattatcc tgtaataggt
     2641 tacatttaaa tttcaatata aatgaaatta gttgttataa aataaacaat ttttttgtta
     2701 agaaatagta aaagaaatat aataaaaaat atcaaaaata aaactaatta taagacataa
     2761 atttacaata aagttacatt tgattaaatt ccttgtttaa caaaagctat tcaaatataa
     2821 tctaaggtag ttttgaaatg ggaactctat tatgcaaatt taagctagtg ttaaaatgag
     2881 gtgaagttat gggcagaaga acaacaagag tttcaagatt aggtaaagaa aaaaaacgaa
     2941 gtgttttaat tgtattggca gctttagttc taataatggg tggatttact tattttttta
     3001 acagtaaatt tctgtacaat gggaaaatcg ctaaaaatgt atatatagaa ggagtaaatg
     3061 tatctgatat gactaaagca gaggcattaa aagctataac agataagtat actccagaag
     3121 acttaaatct tgcttatgat gggaaaaaat atacaatatc accaaaagat attgatttaa
     3181 aatatgatac agaagatgtt gtaaaagatg cttatgaaag tacaaaaaaa gggtcctatt
     3241 ttcaaaactt aaaaaaatat attgatataa gagtgaataa ggcaaatatg aagataaaag
     3301 ctgaatatga tgaggcaaaa cttagttcca aagtgtcttc tatagcagat agtataaatg
     3361 ttaagatgaa aaatgcttct attagtgttg gaagtggtgg actaagttat acagactctg
     3421 ttgtaggtag agaatttgat ttggcagcaa ataaagagtc tatatataat atgataaaaa
     3481 ataaagagca taaaacttta gaacttaaag taaatcttca aaaaccagat ataacaactg
     3541 aacaagtaaa aactgtaaat tctgttatag gtcaatattc aactacttat tcacaagctg
     3601 tagagggtag gtcatataat gtaggattat cagcaagaaa aactagtgat gtattattaa
     3661 tgccaggtga agaattttca tacaataaac ttacaggacc tagtaataaa gcaaatggtt
     3721 acaaagatgc acctgttata gtttatggta agctagaaca atcagcagga ggaggtgttt
     3781 gtcaaacatc ttcaacagtt tataatgctg ctcttctttc gggtatggag ataactcaag
     3841 ttacaaatca ttcatctgca tctacttatg tgcctaaagg gagagatgct actgtgagcg
     3901 atggaggatt aaacttaaag tttaaaaatc catataagca tcctgtatat attaaaaatt
     3961 atgcaggtgg aggaagtgta tcatcagtaa tctatggtaa ttctggtgac aaaccaaata
     4021 tatctataga ggtaaaacaa actggtcaga ataaatattc tacatatcga atatttaaag
     4081 attcaagtgg aaaggtcata aaaaaagaac atatatcaaa tagttcttat aaagaattaa
     4141 aaaaatagat aattttttag agaaatattt gtaatataaa agggagtgtc tcaaaatgaa
     4201 ctttttagtt tatgaggcac tctttttctg tgaaatcaaa tatattttca tcatttcaac
     4261 aatacaaaag aagcgtatct ctattttgag acagcctttt ttgtaaaaat taacactatt
     4321 agttcttgtt ttaatattac aatcattaat atatagaaaa tattcctata tattggtata
     4381 attgtaaata gatttagtta tataaaatgt atgaggaggt gacatggttg aattttatag
     4441 gcaatagata tgaggtagta aattctgatg acgttttaga aattaacaaa atctataaag
     4501 ctagagatgt tttttacagg aaaaatgtgt taataaaagt tataaagcac aataattata
     4561 tctgtgaaga ttttgtttca aatttaattg atgaaagtac tgctttagat gagataaact
     4621 ctccttatat actaaaaata atagatgttg ggattcactg tacagaagaa acaacattat
     4681 attatgttgt aagtgaagac tttaatggta tcggactaga tgaattaatt ctaggtaatt
     4741 atcttcattt agaagcaatt gtaaacataa tgatacaagt tttaaaagct ttagaaatga
     4801 tacataggaa tcattcatat catggtagtt taaaatcgag tagtataata gtagatacag
     4861 aatacaatat aaaaatttgt gattttggaa ttacaaaagc aaataatggg gttaatacaa
     4921 gaagctatgg aaacaggaga tatttatgcc cacatcaact atgtataaat tatactgata
     4981 aagaaagtga tttttttgca acaggtctta ttctatttga atctatattt aaaaaattgc
     5041 cttttggaga atcaaattca gaagaaaaaa tgctacaatc tattgataag ggattagatt
     5101 ggaatagtat aaaagcaatt aatggaaata ctgaacttat aaatgttata aaaaggcttc
     5161 ttggaagaaa taataagtat actagagcca atgatattat tattgattta agtaaagtaa
     5221 tgtatgaaaa agcatatata gaagttgaag atgagaaaga agaagagcag aaacaagaca
     5281 aagttataca agttaaaaaa gaatataaaa gtaaaatgag aaaaaaatta cataaaaaac
     5341 ttgttgttgc cggtctagct atagtcatga tttcaatgat tattattagt tccataatat
     5401 aaaaattgta tattaagtat tttaaaatca atgtctataa aggatataca tagaaatttt
     5461 agtgtagtct taaattatga aaggaagtgg ttattatgtt aacaaaaaat aatgaggtat
     5521 taaacgtcta ggagtatttt aacaaatagc cacctgcttt tacagtttag aataaaaaag
     5581 ctgtggctaa aggtcacagc tttttgctac tttttaaagg caggagaata ttaaaaagga
     5641 gcaaattatg agcaatataa aaataatagc aagtaataaa tgttggattg aagatatagc
     5701 aaggaaacaa cttgaagata tttcaaagtt aaatggaatt ttaagagtag taggattacc
     5761 tgacttacat gcaggtaaaa tacctgtagg tttagcagtt gagactaaaa atattattta
     5821 tccacatata attggaaatg atataggatg cggaatgact ttatttaaaa ctggggttct
     5881 aaaaaagaaa tttaaaaaag acaaatggat taagtcactt agtaagatta aagatttgtc
     5941 cgatatagaa ataaaaaaca catataaaga agaatgtcca attttaaatt taggaactat
     6001 agggagtgga aatcattttg tagaaattca atgtataagt gaaatttata ataaagaaca
     6061 atttgaacaa ttaaaatttt catctgatga tattatgatg ttagttcact gtgggtcaag
     6121 aaattatgga gaagatattt taaaaaaatt ttatgataaa gatggacttg aagttgaaag
     6181 tgagaaagct atagattata ttaaaaaaca tgataatgct ttaatgtggg cagagcgtaa
     6241 tcgtgaagct atcagtaaaa aaattatgca gtcaataggt acatctggag atgttgaaac
     6301 aatattctct ataaatcata attttataga gaaaagggaa gataaattta tacatagaaa
     6361 aggtgctgtt tcaagtgaaa gaggagctgt gattatacca ggttcaagag gcagtctatc
     6421 atatatagtt atgcctactg aaaatacaga gatatcttta tattctctat cacatggagc
     6481 aggtagaaaa tggtctcgtt cagtttgtaa atctcgcctt aaaagtaagt ataataaaga
     6541 tactataaaa caaactaaat ttaaaagtca gattatatgt aatgatgtaa atttattatt
     6601 tcaagaagct ccagaggcat ataagaatat agagcagatt attgaaagtt tgatagaata
     6661 tgaacttatt caagtagtgg caactatgaa gccattgatt acttataaag gataattttt
     6721 aaagttaaaa aagattaaaa ttatattata aatagctaat tttatggaac atttaaaagt
     6781 gttttattat tagctatttt tttattttgt agagacgata atttatagag ctaaattctt
     6841 tgatatataa tgattacaaa gttagactgt attggaaaat gcacatacat gaattgatga
     6901 caatataagt gattcccaaa tataaatgaa agtataagct tattttcact ataaaaattt
     6961 tcactgtaca aaaacattaa tgacattatt tttattgaca taaatatata atttatggaa
     7021 taatattaga agcactgata taagtgttta aataagaata gaaaaggaga agtgttttat
     7081 gaaaaaaaat actaacatta atgagtccgg agttaaactt cttaataaat aaggagtttg
     7141 atatataata actccttatt tattaagttg ttcgcaaaat aactattatc aaagtaaatg
     7201 atagggtgat ttaaaagacg ataacttata aataaaggag aaaaaataat gaatagtaat
     7261 acatttgaaa gattacaact aaatgaagtt aaagaattaa taaaaataca ttgtgtaagt
     7321 tcactaggaa aaaatttaat agataaatta actcctagtg ggaatattgg agtagtaaga
     7381 aggaaattag cagaaaataa agaagctaga aagataattg aaaatagtaa tcacatacca
     7441 cttgaaggat tgtttaatgc aggttctaca atagataaaa ttgaaaaagg aatgataata
     7501 gaacctgttg aacttgtaaa tattgaagat tttttaagag gttgtaggaa gatgaaagct
     7561 tttatgttag aaaaagaatt ttattcacct acattaagtt cttatgcctt aaatataaca
     7621 gaatgtaaaa gtatagaaga tgagataaat tactgtataa aatctaataa agttgattct
     7681 aatgctagta aagaattaaa aaagataaga cgaaatatag aaattacaga aggaaagata
     7741 aaagatagat taaataaatt tataacatca actgtaaata aaaagtatat acaagagttt
     7801 ataataagta aaagaaatga tagatatgta ataccaatta aatcttctta taaaaatgaa
     7861 gttaatggta ctatattaga tacatcatca aaaggaaata cggtatttat tgaacctatt
     7921 agtgtttcaa atttaagtac agagttaact atgttaaaag ctgatgaaac tattgaagaa
     7981 tacaaaatat tatcttattt aacagaactt atatttgaga agataagtca gataaaatta
     8041 aatatagaga tactttcaga atacgatatg gtatttgcaa aagctaagta tagtcaaaaa
     8101 ataaaaggaa ttactccaaa aataaataat aatggctata taaaaataat taaaggtaaa
     8161 catccacttc taacaggaga tgcagtacct ttagattttg aaataggcaa aaattataga
     8221 agtcttataa taacaggtcc taatgcagga ggaaaaactg taacccttaa gactgttggt
     8281 ttactaactt taatggttca atgtggattt gatatttctg caaaagaagg tagtgaattt
     8341 agtgtatttg aaaaagtttt tgtagatata ggggataatc aaagtattga aaatgcctta
     8401 agtacttttt catcacatat aaaaaatatt gcagagatta tgagtttatc aaataattct
     8461 actcttgttc tgtttgatga aataggaagt ggaactgaac ctaatgaagg agctggttta
     8521 gcaatatcat tattagaaga gttttacaaa atgggatgta taactatagc atcaactcat
     8581 tatggagaga taaaaaagtt tgctacattg catccagaat ttgaaaatgc tggtatgatg
     8641 tttgataaag aaacgttaga accattgtat aagttaacta ttggaaaatc tgaagatagt
     8701 aatgctcttt ttatttctaa aaaaatggga ataaaaaata gagttttaga tagagctaaa
     8761 gaatatgtaa ttgatagaaa ctacaattta gatttagtta aaagaagtaa gctacaatct
     8821 aatattgaag ataaaaatag ttctgaagtc attttaaact atacagatta taatgtaggg
     8881 gataaggtaa aattactaga tgaagatgat tttggaattg tatataagcc tatggacaag
     8941 tttaataatg tagaagtatt gtttaatgat aattttattt cagtaaatat aaaaagatta
     9001 caacttagca taaaagcatc agaattgtat ccagaagggt atgatttaga tgtattattt
     9061 actagtttta aagaaagaaa attagaaaaa gatattcaaa gaggttcaaa aaaagctctt
     9121 aaaaagattc agaaagaaat tagagagaat agaaaataaa tataaaaagc acaaaagaaa
     9181 gcaatctaaa gagaaaagtt tatctttaga ttgctttctt attaacatat cttcataaat
     9241 ccaatgacta acaagattaa accacttaac caagataagt ttaaatttac gtttttaaca
     9301 aacatatttc ctagtaaaca accaagtaat actgcaatta tatttgatat taaagaaaat
     9361 agaataactt gtatataatt cacacctaca aggccactac caaaaccgat agctaatcca
     9421 tctaaactta aagcaagtgc aagtgtaaat gcttcagcag atttaagcac tttagattta
     9481 cttgtatcta agacatcagg ttcaatactt acattaaaat ttaatttaag gtctaacata
     9541 ttaaaattat aattctttga gtgtatagat tttttcttaa aataagattt aaaaaaactt
     9601 tcaattagtc tagcacttcc taataaaaat aaaataaaga aacatattaa cattgttata
     9661 ttttgaggta aaaagtctct aactattgta cctgcaaaaa gcgatattgc taaaatagct
     9721 gaacaaacta cgctgataat tatatttgaa tataagggaa ctttaacttt atttacgcca
     9781 tatccaaagc ttgtcacaaa ggcatctata caaagagaag taactaataa aattgattca
     9841 atcacagtag attaacatcc tttctcttaa attttgtact tatattagtt atagtattgt
     9901 aaaaatggat aaattgttac agataatcca ataaattgtt gataaaattc caacatcata
     9961 caacacctaa ataacaaaag aatcatatca tataataata taaaaccaat cataataaag
    10021 caggtgaaaa taatggaaca acatagtaag gttgggaatt tcggtgattt gttgaaagtt
    10081 ttattagatg aaaaagaatt atcaatggga gaactaagta aaaaaagtgg aattgataaa
    10141 tctactatat ctcgtatagc taataataaa caaaagccaa atataaatca tttagaaaag
    10201 atggcaatac atttaaatat taacctagaa gaactgttga aagcttcagg atatgaattt
    10261 agaaacagca ataatcaaat atttaatgca gatagtgatt ttagtaactt tgatgatatt
    10321 cttggatttg caaatttaat caatgataag aactttaatg gaaatattga aaaagagtta
    10381 agtaagtgta agttatatgt ccaaacagat gaaggtaaaa aattactttt tgataatttt
    10441 aataaaaaaa tagattctat tgaaaaacaa ggtcaattta cagatagatt aagacaaatg
    10501 tatgctgatt tttgtacaga tggacttaca ataaagaaat atttattgat tggaagtatg
    10561 ctactttact ttgttatatc aacagatgtg attccagact tcgtgttccc aataggattt
    10621 atggatgatt tagtagcatt aaatatagtt acaaaattac ttaaaaatga taagtaagtt
    10681 ttagaatcat att
//
LOCUS       DAJMZY010000122        10589 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.124, whole genome shotgun sequence.
ACCESSION   DAJMZY010000122 DAJMZY010000000
VERSION     DAJMZY010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10589)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10589)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10589
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.124"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            <1..1889
                     /locus_tag="OE968_003248"
     CDS             <1..1889
                     /locus_tag="OE968_003248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HCP7220492.1"
                     /translation="DNDIINDDVILVMSVERLDKIINNILDKKKVIVVRRTFREDKIY
                     NLLSLPQGTNVLIVNDSDETTLETISLFYKIGVTNIRPIPYMNDNNYKNIKIAITPGV
                     PEKVPSFISDIFDLGHRYIDISTFIEIINLLQIDSKEIQSNLVKYSEEIISLDTGIKD
                     KYKELFLKIEELDTILNLSKDGILFTSKDGEINTYNSKVKDILDINEDIYGKYIEDIF
                     VDSLKVLLSEKEILDKVVVFNKKYINVNKKNIYNRDEKMGTYYSLQEITYIKKLEQNL
                     TKKLREKGQIAKYTFKDIKTNSPKMFECIDLAKKVSKSDLSILIRGESGTGKELIAQS
                     IHNNSNRKNQPFIAVNCAAVPENLLESQLFGYDKGTFTGGLKDGKQGLFELANNGTIF
                     LDEIGDMPLELQTKLLRVLQEKQIMPVGSHNVINIDVRIISATNKNLEQMIDNSQFRE
                     DLYYRLNTIPINIPPLRERKEDILIIMEDLINKKLVITPEAKKLIQNYMWKGNIRELQ
                     NVTSYLNIMCEDIVLEKDLPPNLRSSDNKNTSLKLKYSKNDILNILEILILNKESDVG
                     IGRGLILKALLDKNLQITEGKIKKIFEYLKKEELIICSSGRYGSKITQKGEDFYNKLK
                     YKGL"
     gene            2258..3478
                     /locus_tag="OE968_003249"
     CDS             2258..3478
                     /locus_tag="OE968_003249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HCP7220493.1"
                     /translation="MQQALKLKYQTKELGKDFVIESCNSIKPWLINIRRELHKIPELA
                     LEENLTKQKVISYLKEIGIDYMEFTKHNGIMAYILKESADKTICIRADMDALPIEEEN
                     NIPYKSIHSGKMHACGHDAHTTMLLGACKVLHSIKDKLNVNVKFLFQPAEEGFGGAKF
                     LVEDGCLENPKADYIFGLHVMPHIETGLIETKYDTLNASVDTIKISIKGKRAHGAYPE
                     NGIDAIVTASQIVTSLQTIISRNLEPNNAVVLTIGKIYGGDAHNVICEDVKLEGTLRT
                     LNSKTRNFMIDKIAKIVGDTASAFGCVGTLHVSDENYPAVINEKELVDTVISNTKELL
                     GEEKFILRPNPSLGGEDFSFYTEHCKGAFFHLGCKNEEKGLISPLHTSSFNIDEDCLP
                     IGVMMHVMNTLYFN"
     gene            3515..4864
                     /locus_tag="OE968_003250"
     CDS             3515..4864
                     /locus_tag="OE968_003250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCP7220494.1"
                     /translation="MEKAKKLGLFSMILLGINSIIGSGIFLLPGKVYNLAGQNSMFIY
                     IFATLLVLSILLCFAEVGSMFDKKGGAYLYSKKAFGDFIGFEVGTMSWVIRIISWSTL
                     AVGFATALGSFWPESATEYKGYIAAILVTLLSINSLFGIKSTKIMNNVITIAKLVPLI
                     VFIIVGIFFIKFVNIVPSGNVVNSSMGPAIILVFYAFTGFESFIVASGEMENPKKNLP
                     VALITTIFICAIIYILIQIVCMGILGDRLFENSIPIADASSVFVGNYGKVFISVATLI
                     SIFGINIGSSIVTPKCGSSLAEEGSLPAFIGKTNKYGAPYVAIIISLICCIPLVLTGS
                     FEQLAVMSVIARFAQYIPTCLSVIVLRKRTDVKASFKIPFGPVIPIVAILGSLWLLQQ
                     AWAEDISKPITQNRVLIGLGAMLLIAPLYIFMKKNKEIEHKNKSEDSKLYISREKIQ"
     gene            complement(4996..5289)
                     /locus_tag="OE968_003251"
     CDS             complement(4996..5289)
                     /locus_tag="OE968_003251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220495.1"
                     /translation="MISMIMMLIGVLFIVFGIILTAVEIKGKMPGFYGVGQNAVRKNA
                     IGIIAAGIALIFFRNGLDSIDSILTYGVFLVIELVVIGLYFLIRIKYDKDGNL"
     gene            complement(5775..5978)
                     /locus_tag="OE968_003252"
     CDS             complement(5775..5978)
                     /locus_tag="OE968_003252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220496.1"
                     /translation="MSFGKRIEMNNIGVETRGVCTIMCPYTCKMMASSSCNCKNNDYN
                     ARGGSYNTYYNKLIHGQRTPDGM"
     gene            complement(6029..6280)
                     /locus_tag="OE968_003253"
     CDS             complement(6029..6280)
                     /locus_tag="OE968_003253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide maturation system acyl carrier-related
                     protein"
                     /protein_id="HCP7220497.1"
                     /translation="MNYTEKELLLENIFFDVTGINFNKNNNLKKELFFSPSLHIQPRE
                     LLLVFCEVIENFNIKIPEEKLLNRQFTSFDNVLKIINMV"
     gene            complement(6296..7366)
                     /locus_tag="OE968_003254"
     CDS             complement(6296..7366)
                     /locus_tag="OE968_003254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04066 family peptide maturation system
                     protein"
                     /protein_id="HCP7220498.1"
                     /translation="MEKVLIYPFNYNFFTILNHCNKISDIEINSLVSPSGWGLCNKEY
                     NVNNIITKVTNDFQSELKKNSLVWFVDSKENLDLEKFIIPKLKVALKEGKKILYTRDD
                     LNKISRYISHYEFKKINEWNLEKYEIRDIEGISQINTPIIFICGLYGGLDTFDVNIRI
                     GEELRKRGFSILQFGPKKESYLFKMIPIPEFMFDDSISSKTKIINFNHFIKDKEVEAK
                     PDLIIIEVPGELFPFSRKMVGNFGIRAFEISNAVINDCGILCIPSSIYDREYCEELKY
                     FIKGRHGINIDYFSIEKKVIDTYETEVKQKFSYMSLDENFFVEDIEDYEKTFFIHDNK
                     QLLELVDNIVNQLKEYAKVISI"
     gene            complement(7395..8816)
                     /gene="ccpM"
                     /locus_tag="OE968_003255"
     CDS             complement(7395..8816)
                     /gene="ccpM"
                     /locus_tag="OE968_003255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-rich peptide radical SAM maturase CcpM"
                     /protein_id="HCP7220499.1"
                     /translation="MNQKPFIHTFKAGKSYFIYDVNTDKILKVNAAVYNYLNKIEHNL
                     EKESDWNIEIEDEINTLINYGFLKNKRVSKTMHPETKYIKYHIENNLSSIILQVTQNC
                     NLRCDYCIYSGSYSNRVHTNKRMNIDVAKRSIDYLIKNSSQLNEVSVGFYGGEPLLEF
                     DLIKQIVEYVKVVGEGKEIYFNLTTNATLFNEEIIEFFVKNNITTMISLDGGKEIHDK
                     SRKFANTGEGSHDVVLKNVRYIKNKYPEYYKKNITFNTVINSENDYISIDDFISKNET
                     LKDSNFLASTLNNNYSDKEIVSSDEYILGKSYDRFLTLLNKLKFIKDESMSPLSRIER
                     ALLDDFRYEKNIEGRLELPDVWHHGGPCIPGAFRIFVTTDGEFFPCERVSESSKMGMI
                     GNLDSGVDIEKAEKLLNIGKLYEEQCSDCWAYSYCDICIAKIDDTKCNENEIKPHDCD
                     RIRHSTENNMKDYCVLKSLGYQY"
     gene            complement(8838..>10589)
                     /locus_tag="OE968_003256"
     CDS             complement(8838..>10589)
                     /locus_tag="OE968_003256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCP7220500.1"
                     /translation="FFKGVRNCFNMIYLHDKRYLFISMFMAIFQGIVPSISLLVSQNI
                     INNMQTFSKSVKEILVLLIMYLIINIIPSIFQSFYGYYRIKFNKNFEKHIETMMLEKS
                     LTLSLKDFEDDNTYDMINRAQSQKGFNITILSENLISIIRESVSTLSLIVVLSQFQLW
                     LIIVVIVIPVLKSLYSIKLGKEQYDVSVNRTWKERKAWYIDYLLSKGYAYKEIMVFRI
                     GSKLINHYKKLKEDIISQDMNIAKKNFIATLLCTVLDSIVSAGIIGFIIIQGILKKIL
                     IGDATTYIQAVQSIKDNVESIFSLFSSVIQDLFYTDLLFKFLDYNCKEDSIEHIKIFE
                     KIGDINKIELINISYKYNHSSEYSLKNINLTLNKNDPIAILGKNGSGKTTLLKILLGF
                     YDDYEGDILINGKNLKDIEKDEYIRKVSCMFQDYIKYEATLKENVAMGDVYKSNLEEK
                     VKSKLKETKLKPSIYEEDGLETILGTWFGKKQLSMGEWQKVAISRTLMKDADMYIFDE
                     PDSSLDSEAGNELLSLYKKTFENKIGIFITHHIQHAKKITNNIVVLENGKLLESGRHD
                     ELMDKKGVYFNLFCNCK"
BASE COUNT         3999 a         1469 c         1236 g         3885 t
ORIGIN      
        1 atgataatga tattataaat gatgatgtga tattagtaat gtcagtagaa agattagaca
       61 aaattataaa taatatacta gataagaaaa aagtgattgt ggtaagaaga acttttaggg
      121 aagataaaat ttataatcta ctatctttac cacagggtac aaatgttcta atcgtaaatg
      181 attctgatga aactactcta gaaactataa gtttatttta taaaattgga gtgactaata
      241 ttagaccaat tccatatatg aatgataata actataaaaa tataaaaata gctataactc
      301 caggagttcc agaaaaagta cctagcttta tctcagatat atttgattta ggtcacagat
      361 atatagatat ctctacattt atagaaataa taaatttatt acaaattgat tcaaaggaaa
      421 tacaatctaa tctagttaaa tactcagaag aaataataag tttagatact ggtataaaag
      481 ataaatataa ggaattattt ttaaaaatag aagaattaga tacaatcttg aatttatcaa
      541 aagatggtat attatttact tcaaaagatg gtgaaataaa tacatataat agtaaagtaa
      601 aagatatttt agacataaat gaggatatat atggaaaata cattgaggat atatttgtag
      661 atagtttaaa agttttattg agtgagaaag agatactaga taaagttgtc gtattcaata
      721 agaaatatat aaatgtaaat aaaaaaaaca tatacaatag agatgaaaaa atgggcacat
      781 attatagttt acaagaaata acatacataa aaaaattaga acaaaatctc actaaaaaat
      841 taagagaaaa aggacaaata gcaaaatata catttaagga tataaaaaca aatagtccta
      901 aaatgtttga atgtatagat ttagctaaga aggtttctaa atctgattta agcatactta
      961 tcagaggtga aagtggaact ggtaaagaac tcatagctca gtctatacat aacaactcaa
     1021 atagaaaaaa tcaacccttt atagcagtaa attgtgcagc cgttcctgaa aatttattag
     1081 aaagccagct attcggatat gacaagggaa cttttactgg aggtctaaaa gatggaaaac
     1141 aaggattatt tgaacttgct aataatggaa caatattctt agatgaaata ggcgatatgc
     1201 ctttagaatt acaaacaaaa ctacttagag ttcttcaaga aaagcagata atgcctgttg
     1261 gatctcacaa tgtaattaat atagatgtta gaatcatatc tgctacaaat aagaatttag
     1321 aacaaatgat tgataatagc caatttagag aggatttata ttatcgatta aatacaattc
     1381 caataaatat acctcctcta agagaaagaa aagaagacat attaattatt atggaagatt
     1441 taattaataa gaaattagta atcacaccag aagcaaaaaa acttatacaa aactatatgt
     1501 ggaaaggtaa tataagagaa ctccaaaatg ttacatccta tttaaacatt atgtgtgaag
     1561 atattgtatt agagaaagat ttacctccaa acttaaggtc ttcagataac aaaaatacat
     1621 cattaaaact aaaatatagt aagaatgata tattgaatat attagagata ctaattttaa
     1681 ataaggaatc agatgttggt attggtagag gattaatttt aaaagcacta ctcgataaga
     1741 accttcaaat tacagaagga aaaattaaaa aaatatttga atatctaaaa aaagaagaac
     1801 ttataatttg tagttcagga agatatggaa gtaaaataac tcaaaaagga gaagattttt
     1861 acaataaatt aaaatataaa ggtctataaa attataattt atcaaacaaa gaaatctatt
     1921 caggattaaa gtactccttc aataggtttt tttatttttc aagtacccta aaattataat
     1981 ttattttgta cataaataat aggaattaat aggaatagga taattttttt atttcctatt
     2041 ttttttatat aaactagcat ataaaatata ttttcttcaa aataatattt tttactgaaa
     2101 attgaaacta tgcaatcatt ttttatacta tacatataga taaatgatta tatttattca
     2161 atattcttat aaaaaacaaa attctccatc gaaaattatg gcataataat tgcttattat
     2221 attaataaaa caataaaaag caattggagg aataaaaatg caacaggctt tgaaattaaa
     2281 atatcaaacc aaagaattag gaaaagattt tgtaatagaa agttgtaatt ctataaaacc
     2341 atggcttata aacataagaa gagaattaca taaaattcca gaattagctc ttgaagaaaa
     2401 tcttactaaa cagaaggtaa tttcttattt aaaagaaatc ggaattgatt atatggaatt
     2461 tacaaaacac aatggaatta tggcatatat tttaaaagaa agtgcagata aaacgatttg
     2521 tataagagca gatatggatg ctcttcctat tgaagaagaa aacaacatac cttataaatc
     2581 aatacattct ggaaaaatgc atgcttgtgg ccatgatgca catacaacca tgctacttgg
     2641 agcatgtaaa gttttacatt caataaaaga taaacttaat gtaaatgtaa aattcttatt
     2701 tcaaccagca gaagaaggtt ttggaggagc aaaattttta gttgaggatg ggtgtttaga
     2761 aaaccccaag gccgattata tattcggact tcatgttatg ccacatatag aaacaggcct
     2821 tatcgaaaca aaatatgata cattaaatgc tagtgtagac actataaaaa taagtatcaa
     2881 aggtaaaaga gctcatggtg catatcctga aaacggtatt gatgcaatag ttacagcttc
     2941 acaaattgtt acatcattac aaactataat aagtagaaac ttagaaccaa ataatgctgt
     3001 tgttttgact ataggtaaaa tatatggtgg tgatgcacac aatgtaatat gtgaagatgt
     3061 aaaattagaa ggcactttaa gaaccttaaa tagcaaaaca agaaacttta tgattgataa
     3121 aatagctaaa attgttggag atactgcatc tgcatttggt tgtgttggga ctttacatgt
     3181 aagtgatgaa aactatcctg ctgttataaa tgaaaaagaa ttagtagata cagttatatc
     3241 aaatactaaa gaattacttg gagaggaaaa atttatattg agaccaaacc cgtctttagg
     3301 tggtgaagac ttttcttttt acacagaaca ttgtaaagga gcattcttcc atttaggatg
     3361 taaaaatgag gaaaagggct taatttcacc tcttcatacc tctagcttta atatagatga
     3421 agattgttta ccaataggtg ttatgatgca tgtaatgaat actttgtatt ttaattagta
     3481 cagtaattaa taaaagaata ggagataaat taatatggaa aaagctaaga aattaggtct
     3541 atttagtatg atattattag ggattaatag cataataggt tcaggtatat tcttactacc
     3601 aggtaaagtt tataatctag caggtcaaaa cagtatgttt atatacattt ttgctacact
     3661 cttagttcta tcaatacttt tatgttttgc agaagttgga agcatgtttg ataagaaagg
     3721 aggagcatat ctatactcca aaaaagcttt tggagatttt ataggatttg aagttggtac
     3781 aatgtcttgg gttattagaa ttatatcatg gtctactcta gcagtaggat ttgcaacagc
     3841 tttaggttca ttttggccag aatctgccac tgaatacaaa ggttatatag ctgcaatact
     3901 cgtaacacta ctttcaataa atagcttatt tggaattaaa agcacaaaga taatgaataa
     3961 tgtaataact atagctaaat tagtaccatt aatagttttt ataatagttg gaatattttt
     4021 tataaaattt gtaaatattg ttccttcagg aaatgtagtt aactctagta tgggtccagc
     4081 cattatatta gtattttacg catttaccgg ctttgaatca tttattgtgg caagtggaga
     4141 aatggaaaat cctaaaaaaa atcttccagt cgcattaata accacaatat ttatatgtgc
     4201 aataatttat atattaattc aaattgtctg tatgggtata cttggagata gactatttga
     4261 aaacagtatt ccaattgcag atgcttcaag tgtatttgta ggcaattatg gtaaagtttt
     4321 catatctgta gcaacattaa tatctatatt tggtataaat ataggttcat caatagtaac
     4381 tcctaaatgt ggttcttctc tagcagaaga aggttctctt cctgcattta taggaaaaac
     4441 aaataaatat ggtgctccat atgtagcaat aataatatct ttaatttgtt gtataccact
     4501 tgtgctaact ggaagttttg aacaacttgc agtaatgagc gtaattgcaa gatttgctca
     4561 gtacatacca acttgtttat cagtaatagt tttaagaaaa agaacagatg ttaaggcctc
     4621 ttttaagatt ccatttggcc ctgttatacc aatagtagct attttaggta gcttatggtt
     4681 gttacaacaa gcttgggcag aagatatttc aaaacctata actcaaaata gagttttaat
     4741 aggattaggg gcaatgttgt taatagctcc tctatatata tttatgaaaa aaaataagga
     4801 aatcgagcat aaaaataaat cagaagattc taaattatat atttcgagag aaaaaattca
     4861 ataatatttt atactattac ttctcataaa atataataaa tataaaaaaa ttgtagataa
     4921 aactatttta taaaatttat ctacaatttt tttatataaa catatatcaa aatcaaaata
     4981 ttattaattt atactttaaa gattcccatc tttatcatat tttattctta taagaaaata
     5041 taatcctatt actactaact ctatcactaa aaatactcca taggtaagaa ttgaatcaat
     5101 actatctaac ccatttctaa aaaaaattaa tgctatacct gctgctataa tccctatagc
     5161 attttttctt actgcatttt gcccaactcc ataaaaacct ggcatttttc cttttatttc
     5221 gacagcagtt aaaattatcc caaacactat aaataatact ccaataagca tcataatcat
     5281 actaatcatc taattacctc cttcacttaa ggaaatttca atttctaaaa tctaaaataa
     5341 ataatattta ttttttataa taatattgta tatccaatta actattttgg aaattagtac
     5401 caataaataa tgtttaaata ttgaaataat atattaattc taatcaatat tattaatata
     5461 tatatacatt tttacaaata tatttaaaaa ctttactttt aattcttact atttaaataa
     5521 gtataattta ttataataac ttttaattaa tttatacttt taaattgtaa aaatcacccc
     5581 taatcactat atttaccact ataataattg aagaggtgat ttatataaca gatactattt
     5641 atgcagttat tataaaatca cactcttaat tataatcaac tgcatatttt tataataaaa
     5701 ggaaataaag taagaaagat aaatttaatc aaatatgcta aatcaattta atagtatact
     5761 tattactgaa atatttacat tccatcagga gttctttggc catgtatcaa tttattataa
     5821 tatgtattat atgatcctcc tcttgcatta taatcattat tcttgcagtt acaagatgaa
     5881 gatgccatca tcttacaagt ataaggacac ataatagtac aaacacctct tgtctcaaca
     5941 cctatattat tcatttctat tctttttcca aaactcattc atatcctccc cttttctata
     6001 agatcactta ctttatacct ttattaacct ataccatatt gattattttt agaacattat
     6061 caaaactcgt aaattgccta ttcaaaagtt tttcctctgg aatttttata ttaaagtttt
     6121 ctattacctc gcaaaatact aaaagtaatt ctcttggctg tatatgtaaa gacggtgaaa
     6181 aaaataattc tttttttaaa ttgttatttt tattaaaatt aattccagtc acatcaaaaa
     6241 atatattctc tagtagtaat tccttttcag tgtaattcat aattaacctc caattctaaa
     6301 tagatattac tttagcatac tcttttaatt gattcactat attgtccact aattctagta
     6361 attgtttatt atcatgtata aaaaatgttt tttcataatc ttctatatct tcaacaaaaa
     6421 agttttcatc taatgacata tatgaaaatt tttgcttcac ctctgtctca tatgtatcta
     6481 taactttttt ctctatacta aaatagtcta tatttatacc atgtcttcct ttaataaaat
     6541 atttaagttc ttcacaatat tctctatcat atatacttga tggaatacat aatataccac
     6601 aatcatttat tactgcatta gaaatttcaa aagctctaat tccaaaatta ccaaccattt
     6661 ttctagagaa agggaataat tctcctggaa cttctataat tattaaatct ggctttgcct
     6721 ctacctcttt atcttttata aaatggttaa aattaataat ctttgtctta ctacttatcg
     6781 aatcatcaaa cataaactct ggtataggaa tcattttaaa taaatagctc tcttttttag
     6841 ggccaaattg taatattgaa aacccccttt ttcttagttc ttctcctatc cttatattta
     6901 catcaaaagt atctaaccct ccataaagac cacaaataaa tattattggt gtgtttatct
     6961 gtgatatacc ctctatatct cttatttcat atttttctaa attccattca ttaatctttt
     7021 tgaattcata atgagatata tacctagata ttttattaag atcatcacgt gtatataata
     7081 tctttttacc ttcttttaga gctactttta atttaggaat tataaatttt tctaagtcta
     7141 gattttcttt tgaatcaaca aaccatacca aagaattctt tttaagttca ctttgaaaat
     7201 catttgtaac tttagtaata atattattaa cattatactc cttattgcat aacccccagc
     7261 cagaaggact aaccagtgaa ttaatttcta tatctgaaat tttattgcaa tgatttaaaa
     7321 tagtaaaaaa attataatta aatggatata taagtacttt ttccataatc ccatctttcc
     7381 tttcattaga aaatttaata ttgatatcct agagatttca aaacgcagta atctttcata
     7441 ttattttctg tagaatgtct aattctgtca caatcatgtg gttttatttc attttcatta
     7501 catttagtat catcaatctt agctatacat atatcacaat aactataggc ccaacaatca
     7561 gaacattgct cttcatataa ttttcctata tttaaaagtt tttcagcctt ttctatatct
     7621 actccactat ctaaatttcc aatcataccc attttagaac tttcacttac tctctcacat
     7681 ggaaaaaatt ctccatctgt agttacaaat attctaaaag ctcctggtat acatggtcca
     7741 ccatgatgcc acacatctgg taactctaat ctaccttcaa tatttttctc atatctaaaa
     7801 tcatctaata aggctctttc tattcttgat aaaggtgaca tactctcatc ttttataaat
     7861 tttaatttgt tgagtaaagt caagaatcta tcataactct tacctaatat atattcatct
     7921 gatgaaacta tttctttatc agaatagtta ttattaagag tggaagctaa aaagtttgaa
     7981 tcttttaaag tctcattttt agatataaaa tcatctatag aaatgtaatc attttctgaa
     8041 tttatcactg tattaaatgt aatattcttt ttataatatt ctggatattt attttttatg
     8101 taacgtacat tttttaatac aacatcatga gatccttctc ctgtatttgc aaattttcta
     8161 cttttatcat gaatttcttt tcctccatct aaactaatca tagttgttat attatttttt
     8221 acaaagaatt ctattatttc ctcattaaat aaagttgcat ttgtagttag attaaagtat
     8281 atttcctttc cttctccaac tacttttaca tattctacta tctgcttaat caaatcaaac
     8341 tcaagtaagg gttctcctcc ataaaagcca acactaactt catttaattg actagaattc
     8401 ttaatcaaat agtcaatact tctttttgct acatctatat tcattctttt atttgtatga
     8461 actctgttgc tgtatgaacc agaataaatg caatagtcac aacgtaaatt acaattttgg
     8521 gttacttgta aaataataga ggatagatta ttttctatat gatattttat atacttagtt
     8581 tcagggtgca ttgttttact taccctttta ttttttagaa atccataatt aatcaaggta
     8641 ttaatttcgt cttctatttc tatgttccag tcactttctt tttctaaatt atgctcaatt
     8701 ttatttagat aattataaac agcagcattt acctttaaaa tcttatccgt attaacatca
     8761 taaataaaat atgattttcc agctttaaat gtgtgtataa atggtttttg attcattaat
     8821 taacctccct ttaatattta tttgcagtta caaaataaat taaaataaac accctttttg
     8881 tccataagtt catcatgtct tccactttct aacaactttc cattttcaag aactacaata
     8941 ttgttagtta tcttttttgc atgttggata tggtgcgtta taaatattcc aatcttattt
     9001 tcaaatgttt ttttatataa agaaaggagt tcatttcccg cttcagaatc taaagatgaa
     9061 tctggttcat caaaaatgta catatcagca tctttcataa gagttctaga tattgctact
     9121 ttttgccatt cacccataga aagttgcttc ttaccaaacc aggttcctaa aatagtttct
     9181 aatccatctt cctcataaat acttggtttc aatttagttt ctttaagttt acttttaact
     9241 ttttcttcca agttactctt atatacatct cccatggcga cattttcttt taatgtagcc
     9301 tcatatttaa tataatcttg aaacatacaa cttacttttc taatgtattc atctttttca
     9361 atatccttta aattttttcc atttatcaag atgtcacctt cataatcatc ataaaaacct
     9421 aataatattt ttaaaagtgt cgttttacct gaaccatttt ttcctagtat agcaatggga
     9481 tcatttttat ttaaagttaa attaatattt tttaaagaat actctgatga atgattgtat
     9541 ttatatgaaa tatttattaa ctctatttta tttatatccc ctattttttc aaatattttt
     9601 atatgttcaa ttgagtcttc tttacagtta taatctagaa atttaaacag taaatctgta
     9661 taaaaaagat cttgtattac tgaactaaat aacgaaaata ttgattcaac attatccttt
     9721 atagattgaa ctgcttgtat atatgtagtc gcatctccta ttaaaatctt ctttaaaata
     9781 ccttgaatta ttataaatcc tataattcct gcagatacaa ttgaatctaa aactgtacat
     9841 aatagcgtag caataaaatt ctttttagct atattcatat cttgagatat aatatcctct
     9901 tttaattttt tataatgatt aataagttta gaaccaattc taaataccat aatctctttg
     9961 taagcataac cttttgacaa caaataatct atgtaccagg cctttctttc tttccaagtt
    10021 ctgtttacac taacatcata ttgttccttt cctaatttaa tggaatataa tgatttcaat
    10081 acaggaataa caataacaac tattattagc caaagttgaa attgtgataa tacaacaata
    10141 agagaaagtg tagatactga ttctcttatt attgaaataa ggttttcaga tagtatagta
    10201 atattaaatc ctttttgaga ttgagctcta tttatcatgt cataagtatt atcatcctca
    10261 aaatctttta aactcaaagt taaagatttc tctaacatca ttgtttcaat atgtttttca
    10321 aaatttttat taaactttat tctataatat ccataaaaac tttgaaaaat tgaaggaatt
    10381 atatttatga ttaaatacat aattaacaaa actaatattt cttttacact tttcgaaaat
    10441 gtttgcatat tattaatgat attttgactt actaacaaag aaatagatgg aacaatcccc
    10501 tgaaaaattg ccataaacat agagataaat aaatatcttt tatcatgtag ataaatcata
    10561 ttaaaacaat ttcttacacc tttaaaaaa
//
LOCUS       DAJMZY010000123        10429 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.125, whole genome shotgun sequence.
ACCESSION   DAJMZY010000123 DAJMZY010000000
VERSION     DAJMZY010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10429)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10429)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10429
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.125"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            136..447
                     /locus_tag="OE968_003257"
     CDS             136..447
                     /locus_tag="OE968_003257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HCP7220501.1"
                     /translation="MYFTYIIRCKDDSLYTGYTSNIVRRMNEHKLGINSKYTRAKGFE
                     KLEVYFVTNTKSNAMKLEYYIKKLTRNKKLSIIKNPSILINLIDNKEDYIIGKEIEQL
                     T"
     regulatory      540..632
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            732..1526
                     /gene="thiD"
                     /locus_tag="OE968_003258"
     CDS             732..1526
                     /gene="thiD"
                     /locus_tag="OE968_003258"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HCP7220502.1"
                     /translation="MSNYKIPTLTIAGSDSSGGAGIQADLKTFSAIGTYGMSVITAIT
                     AQNTKGVFAVEDLNKKIIKKQIEAVFEDIPPRAVKIGMVSSPEIILEIVENLKKYNPK
                     YLVVDPVMISKSGYYLLKPEAKENLIKYLIPLAYIITPNIPEAEEITGIKIHNVDDMK
                     RVGEEILQLGPKFVLMKGGHLDGEAVDILVGKNIFKVYKSERIDKKNTHGTGCTLSSA
                     ITSYLALGYEITEAVNLSKIYITEAIKRSFDIGHGVGPVHHFYKFE"
     gene            1550..2338
                     /gene="thiM"
                     /locus_tag="OE968_003259"
     CDS             1550..2338
                     /gene="thiM"
                     /locus_tag="OE968_003259"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HCP7220503.1"
                     /translation="MYNLIKDVKKLNPLVIHYTNNVTINDCANVTLAVGASPLMSFSY
                     EEVEEMVSVANSVVINIGTMNSNMLDLFLLAGKAANKYNKPVVLDPVGVFASKARAEL
                     TSRLLNEVKFSVVKGNVSEIKFIGGFNVRGKGVDSFDEEEDSTEIIRKIAEKLECVVV
                     ATGKIDIITNGKGTYKINNGTDKLKGITGTGCMTASLIASFMAVTENILEAATMGVLT
                     MSLSGELANLNNPPIGTFKENLMNAIYQMDIDTLSKNSNIEFLN"
     gene            2361..2993
                     /gene="thiE"
                     /locus_tag="OE968_003260"
     CDS             2361..2993
                     /gene="thiE"
                     /locus_tag="OE968_003260"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HCP7220504.1"
                     /translation="MIDKESLKKCLKLYLVTDSEMLKGRDFYKCLEDAISSGITTVQL
                     REKNASGREFLRKAMKLREITKQYGVKFIINDRVDIALICDADGVHVGQSDIDVREVR
                     KLIGNNKILGVSARTLEEAICAKNDGADYLGVGSIFTTSTKLDAKSASFETVKEIKEK
                     VDMPFVLIGGINLDNIDKLKCLESDGYAIISAILKAEDISKEVEKWTLKI"
     gene            3132..3434
                     /locus_tag="OE968_003261"
     CDS             3132..3434
                     /locus_tag="OE968_003261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCP7220505.1"
                     /translation="MIRILLVCVGGMSSTLLVNKMEKDAKKRNIDCKIWAVGEGDIKS
                     ELDNFDILLLGPQLRFMLDDVKSIVGDRAPVSIIDMVNYGTCNGHAVLNSVLEILK"
     gene            complement(3500..4249)
                     /locus_tag="OE968_003262"
     CDS             complement(3500..4249)
                     /locus_tag="OE968_003262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCP7220506.1"
                     /translation="MLNILWRSMKWRFKNPISFVVTILQPFLWLVLYSSIANQTMNNI
                     NINNYTAFILPGIIVLVVFSSCSSGGIINFIMKNSGSFYRVLIAPISRYSIVLGQLLE
                     AILVSFIEVTILCIVSIFFSVRIESGIGGILLMIVLIFMTAFFLSSLAYSISLLLPNE
                     IVYETIMTAIVLPIFFLSSALFPIESLSGGLKVAVMLNPFTHVINALRSLIFGETILI
                     GDILPVILLFLILCCSSFSLAMWRLKKEMVS"
     gene            complement(4243..5205)
                     /locus_tag="OE968_003263"
     CDS             complement(4243..5205)
                     /locus_tag="OE968_003263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCP7220507.1"
                     /translation="MLAIEIDNLVKEYKNGVKALNGLSFNVNAGEIFSLLGPNGAGKS
                     SLINILTTFYKPTSGNVTMFGKDLVDNPSWIRTQIACVAQQISIDEHLSLMENMVFQS
                     KMYKVEPQIAKQRIDSLIDKFDLSSYLKYPTSSYSGGVKRRLDIAMNMVSSPKILFLD
                     EPTVGMDVDSRKSMWDMLLKIRDEYGTTIFLTTHYLEEAEQLSDNICIMKNGKDLAQG
                     TPSSLRSYIRQNILRITFHNTEDIKKYKDSIKSTGLVKFMSVRENSIFISVNDSRTAF
                     TLINKWLLEHDIEFDAIEIVEPSLEDVFLALTSSKKSLKEEWEC"
     gene            complement(5209..5667)
                     /locus_tag="OE968_003264"
     CDS             complement(5209..5667)
                     /locus_tag="OE968_003264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HCP7220508.1"
                     /translation="MNCKIEIKNIESVTVATMRYNGPMTEATKYFPNVFKAIKGKSNG
                     APFFCYYDVDQKTGVAEMELCVPTAETPNRMGITTKEFPKTKALFFTHTGSYSNLPKT
                     YEMIFKYIHENNIKIQTPWREVFIKGPGMLIKGNPDNYITEIIFPLKEEE"
     gene            6023..6379
                     /locus_tag="OE968_003265"
     CDS             6023..6379
                     /locus_tag="OE968_003265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCP7220509.1"
                     /translation="MNFELDNTTPIYLQIVKYIKRQIVTGELKPGETIPSRREMALNL
                     KVNLNTVQRAYKEMGDMNIINTFKNYQSSVTVDENILKNLKLELINESLSVFIEDMKA
                     INVSKEEVLKIIEDKY"
     gene            6451..7167
                     /locus_tag="OE968_003266"
     CDS             6451..7167
                     /locus_tag="OE968_003266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCP7220510.1"
                     /translation="MIEIKNVSKTYKRMQGLKIRKIEALKNVSFNIEKGKITALLGIN
                     GVGKSTMLKAIAGLINIDSGEIRIDGEKINEKVYNKLAFVPDVQSHFSNTTIKETFEF
                     MEIFYSKWNKEKSKEMMDIFKLDEDEIIDNLSKGNIARVKLILGFCQDPEYILLDEPF
                     TGIDLFKREEFIGVIAQYMEENQAIIITTHEIVEIESLVDEVVILDEGQIITSFNAEE
                     LREREGKSILDKMREVYKNE"
     gene            7160..7984
                     /locus_tag="OE968_003267"
     CDS             7160..7984
                     /locus_tag="OE968_003267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCP7220511.1"
                     /translation="MNKLLYLINVDLRRSNKFYIAYISFFSLITLSLNLFEINKFKNS
                     KFIMNLAIEDFGGIFYGLGILSNLGFIQSILFFGILGLFIYYVFMWKREFFSNNQSIY
                     TLMMLPQNKFKICISKSIALITMIYGFLISQTATLFICKYIFNFIFRNMPIINMNFAK
                     DLYYLNLKSIPIDFISFMAIYVFLLLIAISIVNCCILFIFSYINKFYVILITLLIIAG
                     LYFSTIYINIITLFRKYYNLIGFQFNNLVAGLLSFLIIMFILNGISYLLIKKKVSL"
     gene            7996..9195
                     /locus_tag="OE968_003268"
     CDS             7996..9195
                     /locus_tag="OE968_003268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220512.1"
                     /translation="MKLKSKISILIIFLTLAIYFSIGLLNNEDNLKIKTIKGDSNELD
                     HININFGYALNGYINSYYTINGSNKTKKTELIKLQKDSKNTNNLIDVSSGSDLIAHVG
                     FEMNEESKDINFVIDEKKEDLEKGVFPSEDSDKEIEYEKLDMNNFTRTRYKVDKSTDD
                     YYAKILSSKRYKKYLYVSVLYATSDSSENNKEYSSTIDIIKINPENKKIKTIKSINLS
                     NYFSEKYQNIENIGVSYASKYEDKMYILVNVLNTNIGDNSNSKFHLLEYNLEENKESI
                     MELKTDSKMALAKAKLEANKLYMVMSNDYDNSSITELNLLTYNILDKSLDEDKYVLDN
                     REKRGIRSIEIDSNKIVAYTSRLNSILSWDDKFMLYIINKNSKEIVYEGELQFNSSNS
                     MLEFEIK"
     gene            9204..10016
                     /locus_tag="OE968_003269"
     CDS             9204..10016
                     /locus_tag="OE968_003269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220513.1"
                     /translation="MKDLIRLFEFELKRNIKNYIFIIICCCSFVILNIVKNLNDYNYI
                     IENAVKSEQLTKIGNTIETVNVTGFSSFRNIMGSTELWFMFGIIACICYAFFIWYRDF
                     NGRSKSIYTLIMLPKNRINIYISKLLNILFLVYSYTVVLTISLFIASKLLPRHMLGNV
                     TNYGFVQETIYELKMLLPYSFEILFVEYIFLLIGFVSVVFTSILINKSIYKVSTLISF
                     LFLVIEILVFIISIEFIIPYEYSDVFTVLYSSINIFVCSLISNKLLKQKIDF"
     gene            10027..>10429
                     /locus_tag="OE968_003270"
     CDS             10027..>10429
                     /locus_tag="OE968_003270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220514.1"
                     /translation="MKAKNIGKYTICFIIVCFLMITMTLILSYFNKDKLSVKTLKGNV
                     KDIGRVSVVYTPNISKFSYEEVIISKNGVRNNTNPKSRIRNDYLNIDKKYSDFVNDKG
                     KEFIYKDDLNIGEAYTSVKSDLVQGMNALNDC"
BASE COUNT         4142 a         1118 c         1652 g         3517 t
ORIGIN      
        1 attagattca tgtagagtat gttttataca tatattataa ttaattcttt gaagattgca
       61 tattcaaaat acacaccatt ttttttaatt ctataatata atatttatat atttaatgtt
      121 aggatgtgat ttaaggtgta ttttacatat attataagat gtaaagatga ttctctatac
      181 actggatata ccagtaatat agttagaaga atgaatgaac ataaattagg aattaattca
      241 aaatacacaa gagcaaaggg atttgaaaaa ctagaagttt attttgtgac caacacaaaa
      301 agcaatgcta tgaagttaga atattatata aaaaaattaa ctagaaataa aaaattgtct
      361 ataataaaaa acccaagtat acttataaat ttaattgata ataaagaaga ttatattatt
      421 ggtaaggaaa tagaacaatt aacataaata tttatagtaa cattataatg ggtgcatatg
      481 gtgtaaaaac ttgacaataa atactattgt aatataatga agttataaat atagtaaatt
      541 aaaatagcta ggggagccaa gagctgagag gtataccgac ccttacacct gatctggata
      601 ataccagcgt aggaaagctt agtaaaaatt caagtatgta ttatttgtga tatatgctat
      661 ttctaagcta tacctattgt aggtatagct tttttaatta agttatttaa attaaacttt
      721 aggaggcaac aatgagtaat tataaaatac caacacttac aatagccggc tctgattcat
      781 ctggaggagc tgggattcag gctgatttga aaacgtttag tgcaattggt acttatggta
      841 tgagtgtaat aacagctata acagcacaga atactaaagg agtttttgct gtagaggatt
      901 taaataagaa aataataaaa aaacaaatag aggcagtctt tgaagatata cctccaagag
      961 ctgtaaaaat aggaatggtt tcaagtcctg agattatact tgaaatagtt gagaatctaa
     1021 agaaatacaa tccaaaatat ttggttgtgg acccagtaat gatatctaaa agtggatatt
     1081 atctattaaa gccagaggca aaagaaaact taattaagta tttgatacca cttgcataca
     1141 taattacacc aaatatacca gaggcagaag aaataacagg aataaaaata cataatgtag
     1201 atgatatgaa gagagtagga gaagaaatac tacaacttgg acctaaattt gtacttatga
     1261 aagggggtca tttagatgga gaagcagtgg atattttagt tggtaaaaat atatttaaag
     1321 tttataaaag tgaaagaatt gataaaaaaa atacacatgg aacagggtgc acattatctt
     1381 ctgcaataac atcttatcta gcattaggat atgaaataac agaagcagta aatctaagta
     1441 aaatctatat aacagaagca ataaaaagaa gttttgatat aggtcatgga gtaggaccag
     1501 tacatcattt ttataaattt gagtaataaa aaaatattgg aggtagaata tgtataattt
     1561 aattaaagat gtaaaaaaat taaatccatt ggtaattcat tatactaata atgtaactat
     1621 aaatgattgt gctaatgtaa ctttagctgt aggagcaagt cctcttatga gtttttcata
     1681 tgaggaagta gaagaaatgg taagtgtagc aaactctgta gtaataaata taggaactat
     1741 gaactcaaat atgttggatt tattcctatt agctggaaaa gcagcaaata agtacaataa
     1801 acctgttgtt ttggacccag ttggagtatt tgcaagcaaa gcgagagcag aacttacaag
     1861 tagactttta aatgaagtca aatttagtgt tgttaaaggg aatgtatcag aaataaagtt
     1921 tataggtggc tttaatgtaa ggggtaaagg tgtagattca tttgatgaag aagaagattc
     1981 tactgagata ataagaaaga ttgctgaaaa gcttgaatgt gtagttgtag caactggaaa
     2041 aatagatata ataactaatg gtaaaggtac atataaaata aacaatggaa ctgataaatt
     2101 aaaaggaatt acaggaactg gatgtatgac tgctagcttg attgcaagtt ttatggctgt
     2161 tactgagaat atattagaag cagcaacaat gggtgttctt acaatgtctt taagtgggga
     2221 attagctaat ttaaataatc caccaatagg tacatttaaa gaaaatctta tgaatgctat
     2281 ttatcaaatg gatatagata ctttaagtaa aaattctaat attgaatttt taaattaata
     2341 aagagtaagg gagacttaaa atgattgata aagaatcttt aaaaaaatgt ttaaagttgt
     2401 atttagtaac tgactctgaa atgcttaaag gtagagactt ttataaatgt cttgaagatg
     2461 caatatcttc tggaataaca actgtacaac ttagagaaaa aaatgcttct ggaagagagt
     2521 ttttaagaaa agctatgaaa cttagagaaa taactaaaca atatggtgtt aagtttataa
     2581 taaatgatag agtggatata gcacttattt gtgatgcaga tggagtacat gtaggacaga
     2641 gtgacattga tgttagagag gttagaaagc ttataggaaa caataaaatt ctaggagtat
     2701 cagcaagaac tttagaagaa gctatttgtg caaaaaatga tggcgcagac tatttaggtg
     2761 tagggtctat attcacaaca tctactaaat tagatgcaaa atcagcttcg tttgaaactg
     2821 ttaaagaaat taaagaaaaa gtagacatgc catttgtact aattggaggt ataaatttag
     2881 acaatataga taaacttaaa tgtttagaaa gtgacgggta tgctataata tcagctatat
     2941 taaaagctga agatatctct aaagaagtgg aaaagtggac attaaaaata taaaattggc
     3001 tctggtagtg aaaaaaatgg aaaaatttga tataatctaa gagtaaaatt taagcaatta
     3061 taaatgataa acttttctac atatactttt taatcaagat atatgtagat ttggttaaaa
     3121 aggagctata aatgattagg atattgttag tgtgtgttgg aggcatgtct tctaccctat
     3181 tggtaaataa aatggagaag gatgcaaaaa aaagaaatat agactgtaaa atatgggcag
     3241 ttggagaagg agatataaaa tcggagcttg ataactttga tattttactt cttggaccac
     3301 aacttagatt tatgcttgat gacgtaaagt ctatagttgg agatagagct ccagtatcta
     3361 taatagatat ggtaaactat ggcacttgta atggtcatgc tgtgttaaat tcggttttag
     3421 aaatattaaa ataaataata aaagtggatt ctatataata gagtccattt ttattatttg
     3481 ttattaatag gcttaaaact tagcttacca tttctttttt taatctccac atagcaagtg
     3541 aaaaacttga acagcacaat attaaaaata gtaggataac aggcagtata tctccaataa
     3601 gaatagtctc accaaatatt aagctacgta aagcgttaat aacatgggta aatggattga
     3661 gcatcactgc tacttttaat cctccagata aactttctat agggaaaaga gctgaactta
     3721 aaaagaaaat aggaagtaca attgcagtca taattgtttc ataaactatt tcatttggca
     3781 ataataaact tatagaataa gctagacttg ataaaaagaa ggctgtcata aatatcagta
     3841 ctatcataag taggattcca ccaatgccag attctatcct tactgagaag aatatactta
     3901 ctatacacaa aatagttact tctatgaaag aaactaagat agcttctaat aattgaccaa
     3961 ggacgattga atacctactg ataggtgcaa ttaagactct atagaaactt ccactgttct
     4021 tcattataaa gtttataata ccaccactac tacaagaaga aaacacaacc agtacaatga
     4081 tacctggtag tataaaagca gtataattat tgatatttat attattcata gtttggtttg
     4141 caatagaact ataaagcaca agccaaagaa aaggttgtaa tatagtaact acaaatgaga
     4201 ttggattttt aaaacgccac ttcatactac gccataagat atttaacatt cccattcctc
     4261 ctttaagctt tttttagaac ttgtaagtgc taaaaataca tcttcgagac ttggctctac
     4321 aatttctatt gcatcaaatt ctatatcatg ttctaaaagc catttattta ttaaagtaaa
     4381 agcagttcta ctatcgttta cacttataaa aattgaattt tctcgtacgc tcataaactt
     4441 tactaaacca gtacttttaa ttgaatcttt atattttttt atatcttcag tattatgaaa
     4501 agttatacgt agtatatttt gtctaatgta actacgtaaa cttgatggtg ttccttgtgc
     4561 taaatccttt ccattcttca taatacaaat attatcactc aattgttcag cttcttcaag
     4621 ataatgagta gttagaaata tagttgtgcc atactcatct ctaattttta ataacatatc
     4681 ccacatagat tttcttgaat cgacatccat accaacagtt ggttcatcta aaaataggat
     4741 tttaggagat gataccatat tcatagctat gtccaatcta cgttttacac cccctgaata
     4801 tgatgaagta ggatatttta agtaactaga taagtcaaac ttatcaatta aagagtctat
     4861 tctttgtttt gcaatctgtg gttctacttt atacatttta ctttgaaata ccatattttc
     4921 cataagggat aaatgttcat caatagagat ttgctgtgct acacaagcaa tttgagtacg
     4981 tatccaagaa ggattatcta ctaaatcttt tccaaacatt gttacatttc cagatgtagg
     5041 tttgtaaaag gtagtcaaaa tatttataag agaagattta ccagcaccat taggaccaag
     5101 taaagaaaaa atttctccag catttacatt aaagcttaga ccatttaaag ctttcacacc
     5161 atttttatat tcttttacta aattgtctat ttcaatcgct aacatatatt attcctcctc
     5221 tttaagtgga aatattatct ctgtaatata gttatctggg tttcctttta tcaacatacc
     5281 tggtccttta ataaatactt ctctccaagg agtttgtatt tttatattat tttcatgaat
     5341 atatttaaat atcatttcat acgtttttgg caaattacta taagagcctg tgtgagtaaa
     5401 aaataaagct tttgttttag gaaattcttt tgtagttata cccatacgat ttggagtttc
     5461 agcagttgga acacataatt ccatttctgc aacaccagtt ttttggtcaa catcatagta
     5521 gcaaaagaat ggtgcaccgt tagactttcc ttttatagct ttaaatacat ttggaaaata
     5581 ctttgttgcc tcagtcatag gtccattata acgcatggta gccactgtga ctgattcgat
     5641 atttttgatt tcaattttgc aattcatttg tttacctcct aatgtgtgtt catattctta
     5701 ctagattttt aagcattaat acatataaga ttttgattag ttgaaaacat ataatcttat
     5761 ctcgtttgct tgttttcaag tctaacataa cataaaatat atatcctctc atttgatgct
     5821 ccattttgta aagttattat ttaagcttta ctttagattt tttagcaaat taaaataaag
     5881 caatttataa aataagtatt tacaaattaa gtgtattaat cgtataatac acttaatagg
     5941 atactagata aagtctgaaa taaaggcgta tttttttaaa gtaagtgtac tatcgtatta
     6001 atacactaga ataggaggaa tcatgaattt tgaattagat aatacaactc ccatttattt
     6061 gcaaatagta aagtatataa agagacaaat agtaacagga gagttgaaac caggagagac
     6121 aataccatca agaagagaaa tggcacttaa tctaaaagta aacttaaata cagttcaaag
     6181 agcatataag gagatgggtg atatgaatat aataaatact tttaaaaatt atcaaagcag
     6241 tgtaacagtt gatgaaaata tattaaaaaa tttaaaatta gagcttataa atgaatcact
     6301 atctgttttt atagaagata tgaaagcaat aaatgttagc aaagaagaag ttttaaaaat
     6361 aatagaagat aagtattagt tttttaacaa atagaaaact tagtttagaa agtttattta
     6421 taagcatatt ggatgtggag gatagtaaat atgatagaaa taaagaatgt cagcaaaaca
     6481 tataaaagga tgcaagggct taaaataaga aagatagaag ctttaaaaaa tgtaagtttt
     6541 aatatagaaa agggaaaaat aactgcatta cttggtataa atggtgttgg taaatcaact
     6601 atgttaaaag caatagcagg acttataaac attgatagtg gagaaattcg tatagatgga
     6661 gaaaaaataa atgaaaaagt atacaataaa ttggcttttg ttccagatgt acaatctcac
     6721 tttagcaata caacaataaa agaaacattt gaatttatgg aaatttttta ttcaaagtgg
     6781 aataaagaaa aatcaaaaga aatgatggac atatttaaat tggatgaaga tgaaataatt
     6841 gataacttgt caaaaggaaa cattgcaaga gtaaaattaa tacttggatt ttgccaagac
     6901 ccagagtaca tacttcttga tgaaccattt acaggaattg atttgtttaa gagggaagag
     6961 tttataggag taatagcgca atatatggag gaaaatcaag ccattatcat aactactcat
     7021 gagatagtag agatagaaag tttagttgat gaggttgtaa ttcttgatga agggcagatt
     7081 ataacttcat ttaatgcaga agaattaaga gaaagagaag gtaaatctat attagataag
     7141 atgagggagg tatataagaa tgaataaact tctatatcta ataaatgtag atttgagaag
     7201 aagcaataag ttttatatag cttatatatc atttttttca ttaattacac ttagtttaaa
     7261 tttattcgaa attaataaat ttaaaaattc taaatttatt atgaacttag caatagaaga
     7321 ttttggaggt atattttatg gactagggat acttagtaat cttggtttta tccaaagtat
     7381 attgttcttt gggatattgg gactttttat atactatgtt tttatgtgga aaagagagtt
     7441 cttttcaaat aatcaaagta tttatacact tatgatgtta cctcaaaata agtttaagat
     7501 ttgtatatct aaatcaatag ccttgataac aatgatatat ggttttttga taagtcagac
     7561 agcaacatta tttatatgta aatatatatt taatttcatt tttagaaata tgcctataat
     7621 caatatgaac tttgccaaag atttatatta tttaaacttg aagagtatac caattgattt
     7681 tatctctttt atggctattt atgtattttt actacttata gctatttcta ttgtaaattg
     7741 ctgtatatta tttatctttt cctatataaa taaattttat gtaattttaa tcactttgct
     7801 gattatagca ggcttatatt tttcaacaat atatataaat ataatcactt tatttagaaa
     7861 atattataat cttataggat ttcaatttaa caatttagta gcagggttat taagtttttt
     7921 aattataatg tttattctaa atggaatatc ttatttgcta attaaaaaga aagtatctct
     7981 ttaaggaggg gtggtatgaa attaaaatct aaaatatcta tacttattat atttttgact
     8041 ttagcaatat attttagtat aggtttatta aataatgaag ataatttaaa gataaaaact
     8101 ataaaaggtg actctaatga attagaccat ataaacataa attttggata tgctttgaat
     8161 ggatatataa attcatatta tacaataaat ggaagcaaca aaactaaaaa gactgaatta
     8221 ataaaactac aaaaggatag taagaacaca aataatttaa ttgatgtatc tagtggttca
     8281 gatttaattg ctcatgttgg atttgaaatg aatgaggagt caaaagatat aaactttgtg
     8341 atagatgaga aaaaagaaga tttagaaaaa ggtgtatttc catcagaaga tagtgataaa
     8401 gaaattgaat atgaaaaatt agatatgaat aattttacaa ggacaagata taaagtagat
     8461 aaaagtacag atgattatta tgcaaagata ctatcatcaa aaagatataa aaaatactta
     8521 tatgtatctg tactttatgc tacaagtgat tcatcagaaa ataacaaaga atattcaagt
     8581 actatagata taataaaaat taatccagaa aataaaaaaa tcaagactat aaaaagtata
     8641 aatttaagta attatttttc cgaaaaatac caaaacatag agaacatagg tgtaagttat
     8701 gctagcaaat atgaggataa gatgtatatt ttagtaaatg tactaaatac aaacataggt
     8761 gataatagta attctaaatt tcatttactt gagtataatc ttgaagaaaa taaggaaagc
     8821 ataatggaat taaaaactga tagcaaaatg gctttagcaa aagcaaagtt agaagctaat
     8881 aaattatata tggtaatgtc gaatgattat gataatagtt caattacaga gttaaattta
     8941 cttacctata atatattaga taaaagctta gatgaagata aatatgtttt agataataga
     9001 gaaaaaagag gaattagaag tattgaaatt gattcaaata aaatcgttgc atatacatca
     9061 aggctaaact ctatattatc ttgggatgat aaatttatgc tatatataat aaataaaaat
     9121 tctaaggaaa ttgtatatga aggagaatta caatttaaca gttcaaatag tatgttagaa
     9181 tttgaaataa agtaggtgag ttgatgaaag atttaataag attattcgaa tttgaattaa
     9241 aaagaaatat aaagaattat atatttataa taatttgttg ttgttctttt gtaattttaa
     9301 acatagtaaa aaatttaaat gactataatt acataataga aaatgcagtt aaaagtgaac
     9361 agttaacaaa aatcggaaat acgatagaaa cggtaaatgt tacaggtttc tcaagcttta
     9421 gaaatataat gggttctaca gaattgtggt ttatgtttgg tataattgca tgtatttgct
     9481 atgctttttt tatttggtat agagacttta atggtagaag taaatctata tatacactta
     9541 taatgctacc taaaaataga atcaatattt atatatctaa attattaaat atattatttc
     9601 tagtgtatag ctatacagta gtacttacaa tatctttgtt tattgcaagt aagttgttac
     9661 ctagacatat gcttggtaat gtcacaaact atggttttgt acaagaaaca atatatgagt
     9721 taaaaatgtt acttccatat agctttgaaa tactatttgt agagtatata tttttattga
     9781 taggatttgt atctgtagta tttacatcaa ttcttataaa taaatctatt tataaagtaa
     9841 gcactttaat aagttttcta tttttagtta tagaaatttt agtgtttata atttctatag
     9901 aatttattat accttacgaa tacagtgatg tatttactgt tctatattca agtataaaca
     9961 tatttgtatg tagtcttata tctaataaac ttttgaagca aaagattgac ttttaggagg
    10021 gatattatga aagcaaaaaa tataggaaaa tatacaatat gttttataat agtatgtttt
    10081 ttaatgatta ctatgacctt aatattgagt tattttaata aggataaact atctgtaaaa
    10141 actttaaaag gcaatgtaaa agatataggg agagtaagtg tagtatatac acctaatata
    10201 agcaaatttt cttatgagga ggtaattata agtaaaaatg gagtaagaaa taatacaaac
    10261 ccaaaatcaa gaattagaaa tgattattta aatattgaca aaaaatacag tgactttgtt
    10321 aatgataaag gaaaagaatt tatatataaa gatgatttga atataggaga agcgtatacc
    10381 tctgttaagt ctgatttagt acaaggaatg aatgctttaa atgattgta
//
LOCUS       DAJMZY010000124        10122 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.126, whole genome shotgun sequence.
ACCESSION   DAJMZY010000124 DAJMZY010000000
VERSION     DAJMZY010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10122)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10122)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10122
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.126"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            313..1788
                     /locus_tag="OE968_003271"
     CDS             313..1788
                     /locus_tag="OE968_003271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HCP7220515.1"
                     /translation="MDSEFANAVELSYECAPLLESLKEYSEKDIACFDVPGHVKNRGV
                     AILNKYLGESLMKMDINSSPTMDNVSAPNGIIKNAQDLLAQAYMADEAFFITNGTTQA
                     IHAMILSVIKPGEKVLLPRNIHKSVINALILCGGIPIFIQPEFDEKLGISLNITLEKV
                     RTEIEKDCNIKALFFLNPTYYGVCADLESIIELCHKNNVLVLVDEAHGAHFPFHLDLP
                     PSAISLGADMVAVSIHKTGGALTQSSALLLNRDNVSFEKVLQSINMLQSTSASYLLMA
                     SIDGARVNLVENGEKQLSKALNLSRYAKSKLNKIDGIKVLSTEILKQKGVKFIDETKL
                     CINVKELNLTGFEVYDLLYKNFSIQVELGDSYNILALVSIGTNKSDIDRLVKALSIIA
                     KIYRKESTLNEFNMVQINPIIKLNPREAFYAPKESVEINSCIDRICGESIMAYPPGIP
                     IIAPGELITEEIMEYIIFLKNSNAYLTDVQDKNLDRILVIK"
     gene            1875..2288
                     /gene="speD"
                     /locus_tag="OE968_003272"
     CDS             1875..2288
                     /gene="speD"
                     /locus_tag="OE968_003272"
                     /EC_number="4.1.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylmethionine decarboxylase"
                     /protein_id="HCP7220516.1"
                     /translation="MKFETLGRHILVEYYNCDENVLKDPRLIENFMNDSALNAKATIV
                     DSVFHHFNPWGVSGAVIIAESHLTIHTWPEYGYAAADFFTCGDIDPWKSFELLEQLLK
                     SERSESTEIPRGLTTKIKKYSKKDLGKITHKPEAV"
     gene            2318..3169
                     /gene="speE"
                     /locus_tag="OE968_003273"
     CDS             2318..3169
                     /gene="speE"
                     /locus_tag="OE968_003273"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HCP7220517.1"
                     /translation="MELWYTEEWTENVRFSIKVNKHLFEGKSQFQRIDVFDSDEFGKF
                     LTIDGLMMVTYKDEFIYHEMITHVPMATNLNIKKVLVIGGGDGGTVRELSRYPQIEKI
                     DMVEIDKMVVDVSKEYMDICSCKLDDKRVSLYFEDGVNFVKCAHDKSYDLIIVDSTDP
                     IGPGEGLFSTDFYKDCYRILTDDGILVNQSESPYFDFNAKEMKRANKKLKQIFPISEV
                     YQAHIPTYPSGHWLFGFASKKLNPVKNQDRNGWEKLSLKTKYYNSDIHLGSFMLPQYV
                     KEMLDEE"
     gene            3159..4037
                     /gene="speB"
                     /locus_tag="OE968_003274"
     CDS             3159..4037
                     /gene="speB"
                     /locus_tag="OE968_003274"
                     /EC_number="3.5.3.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatinase"
                     /protein_id="HCP7220518.1"
                     /translation="MKNNFYHMNTFMSMNKNYEESNLIVFGVGFDGTTSNRPGARFAS
                     SSMRKEFYGLETYSPFLDLDLEDYNICDYGDLEISVGSTEQVLKEIYQETYKIVRDSK
                     VPFMIGGEHLVTLPAFKAVHEKYNDIYVIHFDAHTDLREEYNNSKNSHATVIKRIWDI
                     VGDNKIFQFGIRSGTKEEFKFATEEKHTYMEIGGIDTFENIVNMLNGKNIYLTIDLDV
                     LDASVFPGTGTPEPGGVNYREFQEIFKIIKNSNINIVGCDIVELSPDYDTTGVSTVIA
                     CKILRELCLIISDKIK"
     gene            complement(4203..4403)
                     /locus_tag="OE968_003275"
     CDS             complement(4203..4403)
                     /locus_tag="OE968_003275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000809131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HCP7220519.1"
                     /translation="MKNGIVKWFNNEKGFGFISVEGEDDVFVHFSAIQNDGYKTLEEG
                     EKVSFDITQGNRGPQAENVNRI"
     gene            4870..6360
                     /locus_tag="OE968_003276"
     CDS             4870..6360
                     /locus_tag="OE968_003276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HCP7220520.1"
                     /translation="MFQFETQIHKLRHDVLTAIARLGKEDNLTREAMDNIQYEIIKGE
                     KPTYRCCVYKERAIISERVNVSMGLQPGQDKIDLDTMDIEEDEQIIYILEAACDSCPI
                     NEFTVTDICRGCLAHRCKEACKFGAITHVGGMAYINHELCKACGMCKKACQYDAISEV
                     VRPCKSVCPTNALGFDRENMKAMIHEDKCLNCGACMSACPFGAISDKSLIAPVARKLV
                     QKEKMYAVVAPAITGQVEANVTYGQIKNAIKSLGFVDVLEAACGADAVTVHESLEFAE
                     RMEKGEAFMTNSCCPGFVGYIEKTYPNHVGKISSTVSPMIASGRFIKSHEPDAKVVFI
                     GPCTAKKSEAAKKELKGAVDYVLTFEEIMALFEAFDIDLAKCSNEDIDDASIFGRGFG
                     AAGGLTKAIENYLAEKGIGVNFEPVKISGSREIKKTMTMANLGKLEGNFIEGMMCEGG
                     CINGSGKFLSGAKVKATFDRKNSQSTKKSVLANTKIKDFSNINLEK"
     gene            6640..8136
                     /locus_tag="OE968_003277"
     CDS             6640..8136
                     /locus_tag="OE968_003277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HCP7220521.1"
                     /translation="MFEFETQLKRLKHEVLTAVARLSIEENLTKENIEKIPYEIIKGE
                     KARYRCCVYKEREVVLERAQLALSLTPNSKYGDINPDSVSLDTDEQIIYIVEAACDRC
                     PINEFTVTELCRGCLAHRCKEACKFGAISYINGRAYINHDLCKACGMCKSSCQYDAIS
                     EVVRPCKSVCPTGALDFNRNTMKAMIHEDNCINCGACMSACPFGAISDKSLIAPVAKK
                     LAKKENMYAIVAPAITGQIDSNITYGQLKNAIKSLGFVDMIEASCGADAVTVHESNEL
                     IERIKSGDNYMTNSCCPGFFKYIEKMFPDEKDRISSTVSPMVATGRLVKKIDSDAKVV
                     FIGPCTAKKSEATEKSLKDSVDYVLTFEELMALFEAFNIDLSKCSNEDINDGSIFGRG
                     FGASGGLAKSVQNYIAEKGLSFDFEPIKVSGPRQIKKTMTMAKLGRLEGNFIEGMMCE
                     EGCINGAGKFLSGVKAKNTFDRKNGQSTKKSVLSNDKIKEFEDVNLER"
     gene            8270..9184
                     /locus_tag="OE968_003278"
     CDS             8270..9184
                     /locus_tag="OE968_003278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HCP7220522.1"
                     /translation="MRKIVLKDILFLVTTLSIIVILLLVTNITTNSKIKSTNESYLKS
                     DKNDVSQNNIQSSTKNTAFKTTILSTGKSDCILVEIGNKVIMIDTGEDKNGKQIVDRL
                     KEKGINTLDYLILTHLDKDHIGGVDSVLSSVKVKNIIQANYKKDSKQYDEYIDSLKKA
                     DIEPVLLKDNMNIVINSAEINIHPASKSKYESSNDYSIITNISYGAHKFLFAGDAEEE
                     RLSEFINGNTLKYDFVKMPHHGRYDKLTETFLESISPQYAVITCSEKKEPEEGVLKIL
                     ERLNIKTFLTSNGEVVINSDGKTLSVNQ"
     gene            9302..9493
                     /locus_tag="OE968_003279"
     CDS             9302..9493
                     /locus_tag="OE968_003279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220523.1"
                     /translation="MLDRFFGEGGFGGCAWWIIILFFLFLAFQDCWAEMDLCAWIPFL
                     ILLLILCECGDVFDGGCGC"
     gene            9716..10066
                     /locus_tag="OE968_003280"
     CDS             9716..10066
                     /locus_tag="OE968_003280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220524.1"
                     /translation="MAIVDKIFNEIKLMVARLLLGKKYSEYEEKDLVYNTEEEVILIT
                     LKRLVFQGNVNEAEEILFDKAKSVNSENMQYIAIEFYTMLMEKTDEELEAMNFSKQEV
                     YQGIEDIRKVLNLE"
BASE COUNT         4069 a         1046 c         1810 g         3197 t
ORIGIN      
        1 ttaaaaatag taaactcaaa agcttactaa aactcaaaaa agtaaaaaaa ccaaaataat
       61 aaaaaataag aaagtttata aatactaagt tttaaaaaaa ttaatataaa caacaaaaaa
      121 ttaaaaagtt tataaatatt gatatagcta atgtatatgt ttttgagtaa cttcaaaaaa
      181 acacttgtaa aaatgctggg atgttaatat aataaatatc atgagtttaa taaaagtaaa
      241 aataaaaaat agaaataata aataataaat attaaaaata tttgaatata gagaggagat
      301 gaatttgaaa tcatggatag cgagtttgca aatgcagttg aattaagcta tgagtgtgct
      361 ccattattag agtcgttaaa ggaatactca gagaaagata tagcttgttt tgatgtgcct
      421 ggacatgtaa aaaatagagg tgtagctata ttaaataaat atctaggtga aagtctcatg
      481 aaaatggata taaattcatc accaactatg gataatgtat ctgcgccaaa tgggattata
      541 aaaaatgcac aagatttgtt agcacaagca tatatggctg atgaggcatt ctttataacg
      601 aatggcacaa ctcaagcaat acatgcaatg attttgagtg ttataaaacc aggtgaaaaa
      661 gtattacttc caagaaacat acataaatca gtaataaatg cgttaatact ttgtggagga
      721 ataccaatat ttatacaacc agaatttgat gaaaaactag gtataagttt aaatattact
      781 cttgaaaaag ttagaacaga gatagaaaaa gattgtaata taaaagcatt atttttcctt
      841 aatccaactt actatggagt ttgtgcagac cttgagagta ttatagaact atgccataaa
      901 aataatgttt tagtgttagt tgatgaagct catggtgcac attttccatt tcatttagat
      961 ttacctcctt ctgcaataag tttgggagct gacatggtag ctgtaagtat acataaaact
     1021 ggaggagcat tgacacaatc ttcagcactc ttattgaata gagataatgt aagttttgaa
     1081 aaggttcttc aatcaatcaa tatgctacaa tcaacatcag catcttattt gcttatggca
     1141 agtatagatg gtgctagagt taatctagtt gagaatggtg aaaagcaatt gtcaaaagca
     1201 ttaaatctat ctaggtatgc aaaatctaaa ttgaacaaaa ttgatggaat aaaagtttta
     1261 tctacagaaa tattgaaaca aaaaggtgtt aaatttatag atgaaacaaa attgtgtata
     1321 aatgtaaaag aattaaattt gactggattt gaagtatacg atttattata taaaaatttt
     1381 tcaattcaag tagaattggg agattcatat aatatactgg cacttgtgtc cattggaaca
     1441 aataaatcag atatagatag attagtaaag gcactttcta taattgcaaa gatttataga
     1501 aaagaatcaa cattaaatga atttaatatg gttcaaataa atccaattat taaacttaat
     1561 ccaagagaag ctttttatgc accaaaggaa agtgtagaaa tcaattcatg tatagataga
     1621 atttgtggag aatcaataat ggcatatcca ccaggtatac cgattattgc tccaggagaa
     1681 ttgataacag aagaaattat ggagtatatt attttcttaa aaaatagcaa tgcatatctt
     1741 acagatgtac aagataaaaa cttagataga atactagtaa taaaataaat tactttattt
     1801 tgcaagggca agtgtttgtt aagtagagtt tatcaaatag aacttattaa aagtataaag
     1861 gagttggggt tgaaatgaaa tttgaaacac taggaagaca tatactagta gaatactata
     1921 attgtgatga aaacgtactt aaagacccac gtcttataga aaattttatg aatgattcag
     1981 cattaaatgc aaaagcgaca attgtggatt ctgtattcca ccattttaat ccttgggggg
     2041 tttcaggagc tgttataatt gctgaatctc atttgacaat acatacatgg cctgaatatg
     2101 gttatgcagc agcagatttt tttacttgtg gtgatataga cccatggaaa agttttgaat
     2161 tattagagca acttttaaag tctgaaagaa gcgagtctac agaaattcca agaggcttaa
     2221 ctacaaaaat taaaaaatat tcaaaaaaag atttaggtaa gattactcat aaaccagaag
     2281 cagtataaaa catacaagag aaagtgagga ttattatatg gaactttggt atacagaaga
     2341 atggacagaa aatgtaagat tttctataaa agtaaataaa catctatttg aaggaaagtc
     2401 tcaatttcaa aggatagatg tgtttgatag tgatgaattt ggaaaatttc taacaataga
     2461 tggattaatg atggtaacat ataaagatga atttatatac catgagatga taactcatgt
     2521 tcctatggct acaaatttaa acataaagaa agtattagtc ataggtggag gtgatggagg
     2581 tacagtaaga gaattaagcc gttatcctca aatagaaaag attgacatgg ttgaaataga
     2641 taaaatggtt gtagatgtat ctaaagagta tatggatata tgctcatgta aattagatga
     2701 taaaagagtg agtttatatt ttgaagatgg tgttaatttt gttaagtgtg cacatgataa
     2761 atcatatgac ctgataatag tagattcaac tgacccaata ggaccaggtg aagggctttt
     2821 ctcaactgat ttttataagg attgttatag aatactgact gatgatggaa ttttagtaaa
     2881 tcaaagtgaa agtccgtatt ttgactttaa tgctaaagag atgaaaagag ctaataaaaa
     2941 gttaaaacag atatttccaa tatcagaagt ttatcaagca catataccaa catatccatc
     3001 tggtcactgg ttgtttggat ttgcttcaaa aaaacttaat ccagtaaaaa atcaagatag
     3061 aaatggatgg gagaaattaa gtttaaaaac taaatattat aatagtgata tacatttagg
     3121 ttcgtttatg ttacctcaat acgtgaagga gatgctggat gaagaataat ttctatcata
     3181 tgaacacttt tatgagtatg aacaaaaatt atgaagaatc taatcttata gtatttggtg
     3241 ttggatttga tggaactact tctaacagac ctggggctag atttgcaagt agctctatga
     3301 gaaaagaatt ttacggtctt gagacatata gtcctttttt agatttggat ttagaggatt
     3361 ataatatatg tgattatgga gatttagaaa ttagtgttgg aagtacagaa caagtcttaa
     3421 aagaaatcta tcaagagaca tataagattg ttagagattc aaaggtaccc tttatgattg
     3481 gaggagagca tttagttaca ttaccagcct ttaaagcagt acatgaaaag tataatgata
     3541 tatatgtaat tcattttgat gcccatactg atttgaggga agaatataat aatagtaaaa
     3601 attctcatgc aacagtaatt aaaagaatat gggatattgt aggtgataat aaaatatttc
     3661 aatttggtat aaggtctggg acaaaagaag aatttaaatt tgctacagaa gaaaaacaca
     3721 catacatgga aataggagga atagatacgt ttgaaaatat agttaatatg ctaaatggaa
     3781 agaatattta tctaactata gatttagatg tattggatgc atctgtgttt ccaggaacag
     3841 gtacaccaga acctggtggt gtaaattata gagagtttca agagattttt aagattataa
     3901 aaaactctaa tataaatata gttggttgtg acattgtaga gttaagccct gattacgata
     3961 caacaggtgt atcgacagtt atagcttgta aaatcttaag agagttatgc ttaataatat
     4021 ctgataaaat taaatagagt attttatata aatagtatat attataatat aagaagttat
     4081 tttaagtttg acgcttttct aaagtaactt cttatttttg taattaaaaa taaatataat
     4141 aaacaacaaa aaagagccct cgatagctcc ttttctaaaa tatatatatt taaattaaat
     4201 aattatattc tatttacgtt ttcagcttga ggtcctctat taccttgagt tatatcaaag
     4261 ctaacctttt cgccttcttc taaagttttg tatccatcat tttgtatagc tgagaaatgt
     4321 acgaaaacat catcttctcc ctctacagat atgaatccaa atcctttttc attgttaaac
     4381 cattttacta ttccgttttt cattataaga aaacctccgc attattaaaa aatacaaact
     4441 aaaaaaataa gtctgttcta ttaatataac ataaatttta aataaaagca aataaaattt
     4501 ttaaaaaaat taattacttt tagaatttaa taaaaattgt taaattatac agtgagaagt
     4561 attgtaaaat ttgacgaaaa tgtaaatgta gataataaat ttaatatcaa aaaatgtaac
     4621 aaaaaggtat gtaagtaaaa agtaaaatta aaatatataa taaaaaatat tatatattag
     4681 attgaaaagt aaaaataaaa atagtgaaat ttcagaaata tcaataatat tatataataa
     4741 aacaaaaaaa cactatatat attcgataaa ataaaattta aacatataat attttatgta
     4801 tatattaata aaaggacata ttgtgttata atggtatcgt ataaaatcat ttacgggggt
     4861 ggtattaaaa tgtttcaatt tgaaacacaa atacacaaat taagacatga tgttttaact
     4921 gcaatagcta gacttggaaa agaagataac cttaccagag aagcaatgga taatattcag
     4981 tatgaaataa taaaaggtga gaaacctaca tacagatgct gtgtttataa agaaagagct
     5041 ataatatctg agagagtaaa tgtaagtatg gggttacaac caggtcaaga taagatagat
     5101 ttagatacaa tggatataga agaagatgaa caaattatat atattttgga agctgcatgt
     5161 gacagttgtc caataaatga atttacagta acagatattt gtagaggatg tctagcacat
     5221 agatgtaaag aagcttgtaa atttggagct ataacacatg tcggaggaat ggcctatata
     5281 aatcatgaat tatgtaaggc ttgtggaatg tgtaaaaaag cttgtcaata tgatgccatc
     5341 tcagaggttg ttagaccatg taagagtgtt tgtccaacta atgccttagg atttgataga
     5401 gaaaatatga aagctatgat acatgaggat aaatgtttaa actgtggagc atgtatgtca
     5461 gcatgtccat ttggagcaat atctgataag agtttgatag ctcctgtagc tagaaagtta
     5521 gttcaaaaag agaaaatgta tgcggtggta gctccagcta taacaggtca agttgaagca
     5581 aatgttacat atggtcaaat aaaaaatgct ataaaatcac taggatttgt tgatgtatta
     5641 gaagcagctt gtggagcaga tgcagttaca gttcatgaaa gcttagaatt tgctgaaaga
     5701 atggaaaagg gagaagcttt tatgacaaat tcttgttgtc caggatttgt tggttatata
     5761 gaaaaaacat acccaaatca tgtaggaaaa atatcttcta cagtgtctcc tatgatagct
     5821 agtggtagat ttataaaaag tcatgaacca gatgctaaag ttgtattcat aggaccatgt
     5881 acagccaaaa agagtgaggc agctaagaaa gaattaaaag gagctgttga ttatgtactt
     5941 acttttgaag aaataatggc attatttgag gcatttgata tagacttggc taagtgttca
     6001 aatgaagata tagatgatgc atcaattttt ggaagaggtt ttggagctgc tggtggtctt
     6061 acaaaagcta tagaaaatta tcttgctgaa aaaggtattg gtgttaattt tgaacctgta
     6121 aagatttctg gttcaagaga aatcaagaaa actatgacta tggctaattt aggaaagcta
     6181 gaaggtaatt ttatagaagg aatgatgtgt gaaggtggtt gtataaatgg ttctggtaaa
     6241 ttcttatcag gtgcaaaggt taaagccact tttgatagaa aaaattctca atcaactaag
     6301 aaaagtgtct tagcaaatac aaagataaaa gattttagta atataaattt agaaaaataa
     6361 agataataca aagcaacaaa aatacatatt gttaatagag ttgttctaag ttgaggttta
     6421 acttttggac aactctattt ttatttatat atttaattat tgaacaacta aaataaaaat
     6481 tatatacact taaaataaaa attacatata taatattttg tatataactt aacaaagtat
     6541 atgcctatgt tataataatt tatagaaata aataaaaaat acaatataca taatagtaga
     6601 aatatagcaa aaaggtgtga tttataggga ggattactta tgtttgaatt tgaaacgcaa
     6661 ctaaaaaggt taaaacatga agttttaaca gcagtagcaa gactatctat tgaagaaaat
     6721 ttaacaaaag aaaatataga aaaaattcca tatgaaataa ttaaaggaga aaaggcgaga
     6781 tatagatgtt gtgtttataa agagagagaa gtagttcttg aaagggcgca acttgcatta
     6841 agtttaactc caaatagtaa atatggagat ataaatccag attcagttag tttggacaca
     6901 gatgagcaaa ttatatatat agttgaagca gcatgtgata gatgtccaat aaatgaattt
     6961 acagttacag agctttgtag agggtgtttg gctcatagat gtaaggaagc atgtaaattt
     7021 ggggcaattt cttatataaa tgggagagca tatataaatc atgatttatg taaggcttgt
     7081 ggaatgtgca aaagttcatg tcaatatgat gctatatcag aagttgtaag accttgtaaa
     7141 agcgtttgtc caacaggagc tttggatttt aatagaaaca ctatgaaagc aatgatacat
     7201 gaagataatt gtataaattg tggagcatgt atgtcagcat gtccatttgg agcaatatct
     7261 gataagagtt tgatagcacc tgttgcaaaa aaacttgcaa agaaagaaaa tatgtatgca
     7321 atagtagctc cagctataac aggtcaaata gatagtaata ttacatatgg tcagttaaaa
     7381 aatgctataa aatcactggg atttgtagat atgatagaag cttcttgtgg agcagatgca
     7441 gttacagttc atgaaagcaa tgaacttatt gaaagaataa aatcaggaga taattacatg
     7501 acaaattcat gttgtccggg attttttaag tatatagaga agatgttccc agatgaaaaa
     7561 gatagaatat catctacagt gtctcctatg gtagcaacag gaagattagt aaaaaaaata
     7621 gattctgatg ctaaagttgt atttataggt ccatgtacag ctaaaaagag tgaggcaaca
     7681 gagaaaagtt taaaagattc agtagattat gtacttactt ttgaagaact aatggcatta
     7741 tttgaagcat ttaatataga tttatcaaaa tgttcaaatg aagatataaa tgatggttcg
     7801 atttttggaa ggggatttgg agcatctggt ggacttgcca aatcagtaca gaactatatt
     7861 gctgaaaagg ggcttagttt tgattttgaa cctataaaag tatctggtcc aagacaaatt
     7921 aaaaagacaa tgacaatggc taaattggga agattagaag gtaattttat agaaggaatg
     7981 atgtgtgaag aaggttgtat taatggagca ggtaagtttt tatcaggtgt aaaagctaaa
     8041 aatacttttg atagaaaaaa tggacaatct actaaaaaga gtgttttatc taatgataag
     8101 attaaagaat ttgaagatgt aaatttagaa agataattgt tttggtacag tcattttttt
     8161 atcatgccac aaatatgcct aaaatttgcc ctttttatat gtgtatttta cagagttaag
     8221 gttgctatac tataaatatg taataaataa aatttatagg agcttttgga tgaggaaaat
     8281 agtattaaaa gatatcctgt ttttagttac tacattatct ataatagtaa tattattgct
     8341 tgtaacaaat ataactacta atagtaagat aaaatcaacg aatgaatctt atttaaaaag
     8401 tgacaaaaat gatgtgagtc aaaataatat tcagagtagc acaaaaaata ctgcatttaa
     8461 gactactata ttaagtactg gaaagtctga ctgtatattg gttgaaatag gtaacaaagt
     8521 cataatgatt gatacaggag aagataaaaa tggaaaacaa atagtggata ggttaaaaga
     8581 aaaaggaata aatacacttg actatttaat tttaactcat ttagataagg accatatagg
     8641 tggagtagat agtgtgttat ctagtgttaa agtaaagaat attatacaag caaattataa
     8701 gaaagatagt aagcaatatg atgaatatat tgattcactt aaaaaagctg atatagaacc
     8761 agtgctacta aaagataata tgaatattgt aatcaatagt gcagaaataa acatacatcc
     8821 ggcttcaaaa agcaagtacg agagttcaaa tgattattca ataatcacta atataagcta
     8881 tggagcacat aagtttttat ttgcaggaga tgcagaggaa gaaagattgt cagagtttat
     8941 aaatggaaat actttaaaat atgattttgt taaaatgcct catcatggaa gatatgacaa
     9001 attaactgaa acatttttag agtctatttc accccaatat gctgttatta catgttcaga
     9061 gaaaaaagaa ccagaggaag gtgttttaaa aatattggaa agattgaata taaaaacatt
     9121 tttgacttct aatggagagg tagttatcaa tagtgatggt aagacattga gtgtgaatca
     9181 ataatttttt taaaaatatc taaaaaaatt taaaaaaatc attagcaaat attacccctt
     9241 aaacatagta tattttagga gctgaaactc cacatacaaa atgactagga ggtaacatat
     9301 tatgttggat agattttttg gtgaaggcgg atttggtgga tgtgcttggt ggataataat
     9361 attattcttc ttattcttag cattccaaga ttgttgggct gaaatggact tatgtgcatg
     9421 gatacctttc ttaatattat tattaatact ttgtgaatgt ggtgacgttt ttgatggagg
     9481 atgtggatgc taaaaaaatc aatttagatg atttaataaa gcttatggtg ggtataaata
     9541 aaataccaaa ccaatcacaa tctagtgttt gaaggtagtc ggaaatcccc cgctaccttc
     9601 ttttttttat tgttaaaatt tatttttgaa ttatttcatt tacatataat aatttttacg
     9661 ataaagtctg atataattaa aaagaaaata aaatttattt ataggagatg taaaaatggc
     9721 tatagtggat aagattttca atgagataaa acttatggtt gcaagacttt tattgggaaa
     9781 aaaatacagt gaatatgaag aaaaagattt agtgtataat acagaagaag aagttatact
     9841 tataacttta aaaagattag tttttcaggg aaatgtaaac gaagcagaag aaattttatt
     9901 tgataaagct aagagtgtaa atagtgaaaa tatgcagtat atagcaatag aattttatac
     9961 tatgcttatg gaaaaaactg atgaagaatt agaagctatg aatttttcta aacaagaagt
    10021 ttatcaaggt atagaagata ttagaaaagt attgaattta gaataaaaga tatatgaaaa
    10081 tattgaaata aattaatgct aaggtgagaa tattatactt at
//
LOCUS       DAJMZY010000125         9984 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.127, whole genome shotgun sequence.
ACCESSION   DAJMZY010000125 DAJMZY010000000
VERSION     DAJMZY010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9984)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9984)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9984
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.127"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            172..1053
                     /locus_tag="OE968_003281"
     CDS             172..1053
                     /locus_tag="OE968_003281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HCP7220525.1"
                     /translation="MPAYLFDSNSIANIYRVFPISFSFIVTGLYFSYKNNKNNKINFE
                     AVLEDKKNLIFLLSLMFGMYLYLCLSLSIYYTVGNVLILKLYGIKSAIIVLVGNYIAE
                     RYSFRITQIKGYDIKNQIEYVESVKTEYEINKLNDIVYTDLLTGFYNRPFVNQKLSEW
                     TSNHYKFTLCFTDLNSLKPVNDKFGHQFGDKYISTTAQIIKKLINVENSLLFRYGGDE
                     FLFLLQNTSCVEAEKIMININYELSKISNTDEYPYALSISYGLVEWDGISDIETLISK
                     ADSLMYENKLKNKSTLN"
     gene            1244..1411
                     /locus_tag="OE968_003282"
                     /pseudo
     CDS             1244..1411
                     /locus_tag="OE968_003282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418025.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
     gene            complement(1671..4238)
                     /locus_tag="OE968_003283"
     CDS             complement(1671..4238)
                     /locus_tag="OE968_003283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002602373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate, phosphate dikinase"
                     /protein_id="HCP7220526.1"
                     /translation="MIYYVLPLEHKQATIEIVGGKGMSLSKLLTAGIPVPDGFHVTTA
                     SYQIFVETNHIQSRINKLLDGIDSNNTSQLEDVSKKIGELFHNGEMPQEVSDAIKMAY
                     AGLGNISVAVRSSATAEDLPDASFAGQQETYLNIQGEDKVIDSVKRCWASLWTARAIA
                     YRVKNNIKHEIVALAVVVQKLAFSDSSGIMFTLNPINGRRSEMIINAAWGLGEAVVSS
                     LVTPDTIVVDKDSERIISYEVANKEIMTVRTSEGTEETMVPERLRKKYALTRNQVMQL
                     IQLGKKIEKYYQMPMDVEWALEKDKLYIVQARPITVLPPEWVLPEQDVVYTKGSLAEH
                     LPNPVTPLFATLGLEIVNRASELLWIDMFGKSAKKLLPKNGAYTVINGYVYLSAKSNP
                     LLIAIKSLSPRSLRRTLMNSVARWETARKGYEDAIKQWEEKPLHTMNAHQIMEGIQTI
                     FYAACIYFTRIQLTLPAASISETLFTKLFQGAVRRAGITDTSVFLLGFDTIVLQSEKE
                     LWGISEWVKQNNSINLYLQNSPAIKIAEDFMSSVVPVGVSQEVWIEWKNRINKYFKEF
                     GRTAYEFDFAHSTPQETLTPTFESVKTFVEGKGESPFLRQTTFEKRRKHAEEEILQHI
                     GGLRKKLFFKLLHWAQETSPMRENAIYLMGMGHPLIRCMFQEISERFIRGGAISHLDD
                     IYWLTKSELEVLIEQLDKNKSLSDMNGIIPVRKAELKKYMGYVSPSKLPEKNKKTISQ
                     AQQKQKDGKIVLTGIGTSTGVVTAPACVLNSPADFESFQPGSVLVAVTTTPAWTPLFS
                     SASAIVTDIGGPLSHSSIVAREYGIPAVMATHIATRAIKSGQMITVDGLAGTVTFDE"
     gene            complement(4241..4846)
                     /locus_tag="OE968_003284"
     CDS             complement(4241..4846)
                     /locus_tag="OE968_003284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002591427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCP7220527.1"
                     /translation="MPKGIVLTPEQQAERREKIVAVALSLMAENGFQKTSMREIAVLA
                     NMGKSSLYDFFKTKDEIVVYAVEKEIEKTIQQVHRIIDGEPSPQQCLRKIMLNHLRFP
                     EQYRTVLMWLNTESDYLEEEYRKRLKDARYAYQDIIKSVIDNGVTTGIFRKTDTALVT
                     RLLINSMLSISYTSRPLDSSEKMLDETMNIFLHGIMNDGGE"
     gene            complement(5220..6680)
                     /locus_tag="OE968_003285"
     CDS             complement(5220..6680)
                     /locus_tag="OE968_003285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HCP7220528.1"
                     /translation="MFNELKTKENVYKNLINGKWVESNSRKPIEIYSPIDNSLVGKVQ
                     SMTKHEVDEVIKNTKESIKVWAEMPVYKRANIFHKAADLLLENIDEIANILVLEIAKD
                     IKSARAEVERTADFLRYTADVGKNMEGEAISGDNFPGGTRNKMSYVSRVPLGTVLAIS
                     PFNYPVNLSMSKIAPALIGGNAVVLKPATQGAISALHVVEIMRKAGIPDGVLNTITGR
                     GSEIGDYVVTHKGINFINFTGSTEVGQHISKISGMVPLLLELGGKDAAIVLEDADLDF
                     AAKNIVSGAYSYSGQRCTAVKRILVQESVADKLVGKIKPLVEKLTIGNPMDEVVITPL
                     IDNKATDFVQGLVDDALHKGAKLITGNVRKNNLFYPTLLDNVNVDMKIAWEEPFGPVL
                     PIIRVKDINQAIEIANQSEYGLQSSVFTSDIDKAFYIADKLEVGTVQINNKTERGPDH
                     FPFLGVKASGMGTQGVKYSIEAMTRPKAVVVNVREL"
     gene            7034..7612
                     /locus_tag="OE968_003286"
     CDS             7034..7612
                     /locus_tag="OE968_003286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCP7220529.1"
                     /translation="MAKSFTEIEKDNIRKRLISECEINWSKYGYKKTNIDELCSKSGI
                     AKGSFYTFFDSKEKLFFEVLNGIQNRLISSVDEILSNMPPKEGFAKALKMLYRLYDKN
                     PFLYSPNNTDYITLLNKIPKEMLSQLEYSNVQSFYSLIERHNLKLKIEKEKAFGVCNA
                     LLSSLLLKEDIGYDYIEVFDFMVDNLVEHILE"
     gene            7663..7896
                     /locus_tag="OE968_003287"
     CDS             7663..7896
                     /locus_tag="OE968_003287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220530.1"
                     /translation="MIELIQRLNDIIYKINDKLNIHTKLVDPSSELMPLYSMLSIIVS
                     IFLIILGIKVRKKFLIIIAIISIIINILIILDR"
     gene            7905..9155
                     /locus_tag="OE968_003288"
     CDS             7905..9155
                     /locus_tag="OE968_003288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCP7220531.1"
                     /translation="MVKSSNTFNKNFNLMILGQIISLFGASILKFALSLYILDITGKA
                     EIFATILAVSSIPIIVFSPIGGAIADIFNRRNLMVIFDFSSSLTVLILAVFLFNNNGS
                     ILLVGIIMTILSVISTMYQPTVQSSTPLLVDNEHLMNANGIVAGVASLTNIAGPVLGG
                     VLYGVIGINAIIVISCVSFFLSAIMEIFIQIPFIKQEQNSNIIKTIFTDIKDGIVHIC
                     KENRFILKILFLAIAINLFLSSMLIVGIPYIVKITMGASNFLYGLAEGAISFSSLVAA
                     VSIGIFSKHLKITNLHISFIICAVMFIPMAVSVYPFILNTGFPVPFLIFIVSSMLIFF
                     TTTLISIYVITVTQLKTPNELLGKVMSILFAGTAIAMPLGQVMYGKLFDLLSDRVYII
                     ILGVGFITLLIAFVSKITLRNENL"
     gene            9316..9885
                     /locus_tag="OE968_003289"
     CDS             9316..9885
                     /locus_tag="OE968_003289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HCP7220532.1"
                     /translation="MSYMPTLEQAWEILRKYNKEEFHIRHAQIVSGVMRYYAKEYDPE
                     RVEFWEIVGLLHDLDFEMYPDEHCVKQRELMTELDLDKSIIDSTISHGYGLTGSDVKP
                     EQFMEKVLFAVDELTGLIGAAAIMRPSKSVSDLELKSVKKKFKDKSFAAGCSRDVIRS
                     GAEMLGWELDKLIQTTIEAMRSLIPEMAI"
BASE COUNT         3321 a         1724 c         1492 g         3447 t
ORIGIN      
        1 aagtttcatc taattataaa ttggacaatt tttatgttga ttttattcat acaaattaaa
       61 gtaacttata aaatctccac aataaaaaac attttttatt cactaaactg ctccatcatt
      121 ggtttagcaa taaatatatt ttttaggtct ttaatgtcaa tagtgttaaa tatgccagca
      181 tatttatttg atagtaattc tattgcaaat atttacagag tatttcctat atcatttagc
      241 tttatagtta caggactata tttcagttat aaaaataata aaaataataa gattaacttt
      301 gaggcagttt tagaggacaa aaaaaactta attttcttat tgagccttat gtttggaatg
      361 tacttgtatc tatgtttgag tttgtcaata tactatactg ttggaaatgt attgatttta
      421 aaattatatg gaatcaagtc tgccataata gttttggtag gtaactatat tgcagaaaga
      481 tatagcttta gaattactca aataaaaggt tatgatatta aaaatcaaat agaatatgta
      541 gaaagtgtaa agacagagta tgagattaat aaattgaatg atattgtata tacagattta
      601 ctgacaggtt tctacaatag accttttgtg aatcaaaaac tatcagaatg gacatcaaat
      661 cactacaaat ttaccttatg ttttactgat ttaaatagct taaaacctgt aaatgataaa
      721 tttggacacc aatttggtga taaatacata tccactactg ctcaaataat aaaaaaactt
      781 ataaatgtag aaaattcctt actatttaga tatggtggag atgaattttt attcctttta
      841 cagaatacaa gttgtgtaga agcagaaaag ataatgatta atataaatta tgaattatca
      901 aaaataagta ataccgacga gtatccttat gctctttcca taagctatgg attagttgag
      961 tgggatggaa tatccgatat tgaaacttta atatcaaagg cagattcttt gatgtatgaa
     1021 aataagctta aaaataaatc tactttaaac tagctagttc agatattcta caaaatatat
     1081 attataagat agtactaaga atgtcaaaat atatagattt tgcaaatatt gaatacagtt
     1141 tactaatgaa tgcactggat gtaagtgtta gtaaacacct attagatgaa cactttactg
     1201 ttgtttgggc taatgaccgt tattatgaaa tgttcggcta tacctagcta aaaagttaaa
     1261 aatgaccact gtagccgagg gaatagagac tagttttcaa aaagatttct tgcaagaaat
     1321 agactgtgat atgttacaag gatacgtgtt ctctagacct ttaccaataa aagactttga
     1381 aaaacttatg tttcaaaact cctccaatta acaatataaa attgcttatt ataagtgata
     1441 ttattgtatc aacaaataaa ggaattgtct caaaattgat tttttctaat caaattttta
     1501 ttttgagaca ttctcatttt tttgcataag aaaataccca ccaagctacg gtttttctta
     1561 ccgctgttcg gtgggtatta gtagtattat gaaatctgaa aactttaagt attactactt
     1621 ccgctagcgc aatcacaaag gtcgaaagct tcaaagcgaa aataggcttt ttactcatca
     1681 aacgtcaccg tacctgccaa cccgtccacc gttatcattt gtccgctctt aatagctcgt
     1741 gtggcaatgt gtgtagccat aacggctggg atgccatatt cacgtgcgac aatgcttgaa
     1801 tggctaagag gaccaccaat gtccgttaca atcgcacttg cagatgaaaa taatggtgtc
     1861 catgctggag ttgtggtaac tgcaaccaaa acacttccag gttgaaagct ttcaaaatct
     1921 gctggactat tcagtacaca agctggagcc gtcacaacac cagtactggt accaatgccc
     1981 gtcaacacaa ttttcccatc tttctgcttc tgttgtgctt gtgatatagt ttttttgttt
     2041 ttctctggca acttggatgg tgacacataa cccatgtatt ttttaagttc agcttttcga
     2101 acaggtatta tcccgttcat atcagataga gacttgtttt tatccaactg ctctataagt
     2161 acctccaatt ccgattttgt gagccaataa atatcatcta aatgtgaaat agctcctcct
     2221 cgtatgaatc gttctgagat ttcctgaaac atacaacgaa tcagaggatg tcccattccc
     2281 atcaaataaa tagcattttc acgcatagga gaggtttcct gtgcccaatg gagcaactta
     2341 aaaaatagtt ttttacgcaa tccacctatg tgttgtaaaa tctcttcttc tgcatgtttt
     2401 ctacgctttt caaacgtggt ctggcgtaaa aaaggacttt ccccttttcc ttccacaaat
     2461 gtttttacgg attcaaaagt tggtgtaagt gtttcctgcg gtgtggaatg cgcaaaatca
     2521 aactcataag cggtacgacc aaactcttta aagtacttat tgattcgatt tttccattct
     2581 atccatactt cctgtgaaac tccaacaggc acaactgaag acatgaaatc ttctgctatc
     2641 tttattgcag gactgttttg cagataaagg ttgatgctgt tattttgctt tacccattct
     2701 gaaatacccc acaactcctt ttccgattgc agaacaatcg tatcaaaccc aagcaggaaa
     2761 acggaagtat ccgttatacc agcacgtcga actgctcctt gaaataattt tgtaaataat
     2821 gtttcactga tagaagcagc aggcaatgta agctgaatcc ttgtgaaata aatacatgcg
     2881 gcataaaata ttgtctgaat accctccata atttgatggg cgttcatagt atgcaggggc
     2941 ttttcttccc attgtttaat agcatcctca tatccttttc gtgccgtttc ccagcgtgca
     3001 acgctgttca taagtgtcct acgtaaagag cgtggggaaa gggatttgat agcaatcaaa
     3061 agtggatttg atttagcaga aagataaaca tatccattaa taaccgtata tgccccgttt
     3121 tttggtaata attttttcgc acttttacca aacatatcta tccataaaag ctctgatgca
     3181 cggtttacga tttcaagacc aagcgtggcg aacaaaggtg taacaggatt tggcaaatgt
     3241 tctgccaaac ttccctttgt gtatacaaca tcctgttctg gcaataccca ttctggtggc
     3301 agaacagtaa ttggacgagc ctgaacaatg tacaatttat ctttttccag tgcccactct
     3361 acatccatag gcatttgata atacttctca attttctttc caagctgtat cagttgcatt
     3421 acctgattac gagtaagagc atattttttt ctcaaccttt caggaaccat ggtttcttct
     3481 gttccttctg aagtacgaac cgtcataatc tctttatttg ccacttcata cgatataatt
     3541 cgttcggagt ccttatccac tacgattgta tcgggtgtaa ctaagctaga aaccaccgct
     3601 tcaccaagcc cccatgcagc gttaataatc atttcgctac gtctaccatt gattgggttt
     3661 aacgtaaaca taataccaga tgaatcggaa aatgcaagct tttgtactac aacagcaagt
     3721 gcgacaatct cgtgctttat attattcttc acacgataag caatagcacg agctgtccat
     3781 aaggaagccc agcatctctt tacagagtca ataactttat cttcaccttg tatgttaaga
     3841 taagtttcct gctgacctgc aaaagaagcg tcaggtaaat cttcagcagt cgcagacgaa
     3901 cggacagcca ccgatatgtt ccctaatcca gcataagcca ttttaattgc gtccgacact
     3961 tcctgtggca tttctccatt atggaaaagc tcccctattt tcttagatac atcttcaagt
     4021 tggctggtat tattggaatc aataccatct agcagtttat taattcgaga ctgaatatgg
     4081 ttcgtctcaa caaaaatctg gtatgaagca gtcgtaacat gaaaaccgtc tggcacaggg
     4141 atgcctgctg tcaatagttt tgataaagac atcccttttc caccaacaat ttcaatggtt
     4201 gcttgtttat gttccagtgg caagacataa taaatcataa tcattcacct ccatcattca
     4261 taattccgtg cagaaatata ttcattgttt catccaacat tttttccgaa ctatccaatg
     4321 gtcgtgacgt gtagctgatt gataacatgg agttaattaa caaacgtgtc acaagagcgg
     4381 tatccgtttt gcgaaagatg cctgtggtca caccattatc aattaccgat tttataatat
     4441 cttgatatgc ataacgagca tctttaagtc tctttcgata ctcttcttct aaataatcag
     4501 attctgtatt taaccacatc agtacagttc tatactgctc tggaaatcta agatgattaa
     4561 gcatgatttt tctaaggcac tgttgtggtg aaggttcacc atcaataatc ctatgaactt
     4621 gttggatagt tttttctatt tctttctcaa ctgcatatac aacaatctcg tctttcgttt
     4681 tgaaaaaatc gtatagactt gactttccca tgttggctaa aactgcaatt tctctcattg
     4741 atgttttttg gaatccattt tcagccataa gactcaaagc aacagcaact attttttctc
     4801 ggcgttctgc ttgttgttcg ggtgtaagca caattccttt tggcataggg cgatacctcc
     4861 ttttagcgac cactggtcgt ttctttttta tttatcatac agcgaccaac ggtcacttgt
     4921 caaggttaat ttttttcatt gtatatggta ctcgagataa aaatgttcat tttagaaatt
     4981 gctctattta agtagaaata ggcttcatca ttagaaaaca agactataaa tttgagatat
     5041 ttatcatgtt caaatttcat caatatcaaa gtttaagata ttaataaaaa aagaattact
     5101 aagaaataac atataaagat tcaaaaaagg agttgaactt aaaattcaat tacaaaaaat
     5161 caaatttaag acaactcctt tattctttat ctctactatt ctttatctct atttatttat
     5221 tacaactccc taacatttac cactactgcc ttaggtctag tcatagcctc gattgaatac
     5281 ttaacacctt gagttcccat accagatgcc tttacaccta aaaatgggaa gtggtctgga
     5341 cctctttcag tcttattatt tatttgaaca gtaccaactt caagtttatc agctatataa
     5401 aatgccttat caatatcact tgtaaatact gatgattgaa gcccatactc tgattgatta
     5461 gcaatttcaa ttgcttgatt tatatcttta actcttataa ttggaagtac tggaccaaat
     5521 ggttcttccc aagcaatttt catatcaaca tttacattat ctaacaatgt tggatagaat
     5581 aaattatttt ttctaacatt gcctgttatt aactttgctc ctttatgtaa tgcatcatca
     5641 accaaccctt gaacaaaatc agttgcttta ttatctataa gaggagtgat aactacttca
     5701 tccattggat ttccaattgt caacttctct accaatggct ttatttttcc gactaattta
     5761 tccgccacac tctcttgtac taaaattctc tttactgccg tacatctttg tcctgaatat
     5821 gaatacgctc cagatactat attcttagct gcaaaatcta agtctgcatc ttctaatact
     5881 atagccgcat cttttccacc aagctccaat aataatggta ccattccaga tattttagat
     5941 atatgctgac caacttcagt actaccagta aagttaataa aattaattcc tttatgcgtt
     6001 acaacataat ctcctatctc actaccccta cctgtaatag tattaagtac tccatctggt
     6061 atcccagctt ttctcataat ttctaccaca tgaagtgcgc taatagcccc ttgtgtagca
     6121 ggttttaata caactgcatt tccaccaata agtgctggag caatctttga cattgataaa
     6181 tttacaggat aattaaaagg agatatagct aaaacagtac ctaatggaac ccttgaaaca
     6241 taagacatct tatttcttgt tccaccaggg aaattatctc cactaatggc ttcaccctcc
     6301 atattttttc ccacatcagc tgtgtatctt aaaaaatctg ctgttctctc aacttctgcc
     6361 cttgcagatt ttatgtcttt ggctatttca agtaccagta tattagctat ctcatctata
     6421 ttttctaaca ataaatcagc agccttatga aatatattgg ctctcttata tacaggcatt
     6481 tcagcccata cttttatact ctcttttgtg ttttttataa cctcatctac ctcatgtttt
     6541 gtcatagatt gtactttccc aacaagagaa ttatctattg gtgagtaaat ttctattggc
     6601 tttctcgaat tagattctac ccattttcca tttattaaat ttttatatac attttctttt
     6661 gttttaagtt cattaaacat atttttattc ctctctctga tataactttg tgtatttaaa
     6721 ttatagccat ttattcgtta tgtaaacatt tctttttttc ataaacgttt acctataaaa
     6781 aaattttaag ttaacgtttt tctacattct tctattttaa taacatactc gctccaaatc
     6841 tatataggtc acactttaat atcaatatac taatatacca atataccaat ataccaatat
     6901 accaatatac caatataaat attataaaca taaatcactt gacaaattta taagtagaca
     6961 atattatata tctatgactt aaaatatttt taaagtcata gatatcatat atagatagaa
     7021 aggattgata aaaatggcta aaagttttac agaaatagaa aaagacaata taagaaaaag
     7081 actaatttca gaatgtgaaa tcaactggtc taaatatgga tacaaaaaaa ctaatattga
     7141 tgaactttgt tcaaaatcag gaattgcaaa gggttcattc tacacattct ttgattcaaa
     7201 agaaaagtta ttttttgaag tattaaatgg aatccaaaac agacttatat catcagtaga
     7261 tgaaatttta agtaacatgc ctccaaaaga aggctttgca aaagccttaa agatgttgta
     7321 tcgattatat gataaaaacc cattcttata ttcaccaaat aatactgatt acatcacttt
     7381 attgaataag atacctaaag agatgctttc acaacttgaa tacagcaatg tacaaagttt
     7441 ttatagctta attgaaagac ataatctcaa gttaaaaata gagaaagaaa aagcctttgg
     7501 tgtttgcaat gccctactgt caagcctatt gctaaaagaa gatattggat atgactacat
     7561 tgaagtattt gattttatgg tagacaatct tgtagaacac atacttgagt aataatttaa
     7621 aataaatttt ctaaacattt ctttataact aggaggagta atatgattga attaatacaa
     7681 agactaaatg atattattta caaaataaat gataaactaa atatccacac aaaacttgta
     7741 gaccctagca gtgagctcat gccactttac tctatgttat ctataatcgt ttctatattt
     7801 ctaataatat taggtattaa agtaagaaaa aaattcctta taataattgc tattatatca
     7861 attattataa atattttaat aatcttagat aggtaggtac atatatggta aaatcctcga
     7921 acacttttaa taaaaacttc aacttgatga tattaggtca aataatctca ttgtttggtg
     7981 catcaatact taaatttgct ttatctttat acatacttga tataactggt aaagcagaaa
     8041 tatttgctac tatactagca gtatcttcaa tcccaattat agtattctcc cctattggtg
     8101 gagctattgc agatatattc aacagaagaa acttaatggt tatttttgat ttttcaagta
     8161 gtcttacagt actaatctta gcagtattct tattcaacaa taatggttca atattacttg
     8221 taggaattat tatgaccata ttatcagtca taagcacaat gtatcaacca actgttcagt
     8281 caagtacacc ccttttagtt gataatgagc atttaatgaa tgcaaatggt attgtagctg
     8341 gagttgcatc tcttacaaat attgcaggac ctgtattagg aggtgtcttg tatggtgtga
     8401 ttggaattaa tgcaattata gttataagtt gtgtaagttt ctttctatct gcaattatgg
     8461 agatatttat acagattcct tttatcaaac aagagcaaaa cagcaacatt ataaaaacta
     8521 tatttactga tataaaggat ggtattgttc atatatgtaa agaaaataga tttatactaa
     8581 aaatactttt tttagctata gcaataaact tatttttaag ctctatgtta atagttggta
     8641 tcccctatat agtaaaaatc actatgggag ctagtaactt cttatatggt ctagcagaag
     8701 gagcaatttc ttttagttca ctggtagctg ctgttagtat tggtattttc tcaaaacatc
     8761 taaaaatcac taatttgcat atttccttta ttatatgtgc agttatgttc ataccaatgg
     8821 cggtttcagt atatccattt atattaaaca caggatttcc agttccattt ttaatcttta
     8881 tagtatcatc tatgctaata ttttttacaa cgactcttat ctcaatatat gttataacag
     8941 tcacacaatt aaaaactcca aatgaactct taggaaaagt aatgtcaatt ctttttgcag
     9001 gaacagcaat tgcaatgccc cttggtcagg ttatgtatgg taaacttttt gatttattat
     9061 cagatagagt gtacatcatt atactaggag ttggatttat tacattactt atagcatttg
     9121 tatcaaagat aacattgagg aacgaaaatc tttagataca aagaatttag atataaagat
     9181 ttaattttca ctaatttctg aatttaaatg caaaattgtg tatcagtatg ttgacgtttt
     9241 agaaattgat tgatataatc aatggaaaat aaactttata aaaattcaaa atattcagct
     9301 agaggagtga taaaaatgag ttacatgcca actttagaac aagcatggga aatattaaga
     9361 aaatacaata aggaagaatt tcatataaga catgctcaaa ttgtatctgg agttatgaga
     9421 tactatgcaa aggagtacga ccctgaaaga gtagaatttt gggaaatagt tggactttta
     9481 catgatttag attttgaaat gtatcctgat gaacattgtg ttaaacaaag agaattaatg
     9541 acagagcttg atttagataa atcaataatc gattctacaa taagtcatgg atatggatta
     9601 actggttcag atgttaaacc agagcaattt atggagaaag tattatttgc tgtggatgaa
     9661 cttactggtt taattggtgc tgctgcaata atgcgtcctt caaagagcgt ttctgattta
     9721 gaattaaaat ctgttaagaa gaaatttaaa gataaatcat ttgctgctgg ctgttctcga
     9781 gacgttataa gaagtggtgc agaaatgctt ggatgggaac ttgataagct tatccaaaca
     9841 actatagaag ctatgagaag cttgattcca gagatggcaa tatagctcct ccatacatat
     9901 accatagaag ttacatcttt aaagagcatt tctctttttg atgcaacttc tttttatatt
     9961 ttgtagaata aaaagtttaa tatt
//
LOCUS       DAJMZY010000126         9857 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.128, whole genome shotgun sequence.
ACCESSION   DAJMZY010000126 DAJMZY010000000
VERSION     DAJMZY010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9857)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9857)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9857
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.128"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            562..1470
                     /gene="trxB"
                     /locus_tag="OE968_003290"
     CDS             562..1470
                     /gene="trxB"
                     /locus_tag="OE968_003290"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HCP7220533.1"
                     /translation="MVDIIVIGAGPAGLTSAIYAMRAGLSVTVFEKNIYGGQVASTSE
                     VENYPAVQKISGVEFSNNIYNQAVAQGVDIQFDEVEEINLEGKVKVVKTSSGEHKAKA
                     VILANGVERRKLGCAGEQEFTGRGVSYCATCDGAFFKDKEVAIVGGGNTALEDALFLA
                     NNCTKVYLIHRRDSFRGEEVLEKSVKARENIEILYSHGVEKIEGEKTVSKIEVKNLKT
                     EEKRTIDVSGIFIAIGLKPNNKMFENVLDLDEGGYIISDESCTTSVEGVYVAGDSRTK
                     FLRQIITAASDGAIAAVQAANYINVE"
     gene            complement(1560..3383)
                     /gene="typA"
                     /locus_tag="OE968_003291"
     CDS             complement(1560..3383)
                     /gene="typA"
                     /locus_tag="OE968_003291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HCP7220534.1"
                     /translation="MSQKHKIINIAVIAHVDAGKSTLVDAFLSQSGVFRKNEVVKDCV
                     MDSNDLEKERGITIYSKNCAINYEDYKINIVDTPGHSDFSSEVERVMKTVDTVILLVD
                     ASEGPMPQTRFVLQKSLEFGLKPILFINKIDKKDQRAEEVVNEVFDLFVDLNATDEQC
                     EFPIIYGIAKQGIAKLEMDDDSEDLSPLFKTIVNHVEAYPNYDNEPLQFQISALAYDD
                     YVGRLGIGRIYKGTLKNNTQVAICREDSVVSKGKVSKLSVYEGLKQVEVDEATSGEIV
                     VIAGIPDISIGETICDLDSPLPMEMIKIEEPTLSMNFLVNDSPFVGKSGKFVTTRHLK
                     DRLEKELEVNVGLKVEPLDTTDGYKVSGRGELHLSILLENMRREGYEVGVSKPEVLMH
                     KEDGKLMEPIERVVVNCPEVYSGTIINELNMRKGMMESMSIEGDYVKIEFLAPTRGLL
                     GYRSEFINATRGEGTLVRSFEKFEEFKGEIPSRGNGVLIAQGPGVTMGYSLNALSDRA
                     VMFVDPGVEVYEGMIIGMNSRKDDMVVNPCKNKKMSNVRASGSDDAIKLSPPRIFTLE
                     EALEFIEDDELVEITPDSIRLRKRFLNEHDRLRYNKSRQGK"
     gene            3595..3837
                     /locus_tag="OE968_003292"
     CDS             3595..3837
                     /locus_tag="OE968_003292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220535.1"
                     /translation="MLEVTKIIIKYFASESDTFVKEEVCNFEELLKWSHKFIEGKKIE
                     DVLYIKSKENYKVNVIKSLEIKELEIVRKQQIPPYM"
     gene            3985..4176
                     /locus_tag="OE968_003293"
     CDS             3985..4176
                     /locus_tag="OE968_003293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1450 domain-containing protein"
                     /protein_id="HCP7220536.1"
                     /translation="MIRVCPNCSNVDVNKLKTLVGEENVKTGCIGQCRAFKKEAVGII
                     DNELEIKETEAEFFEACKE"
     gene            4467..6968
                     /locus_tag="OE968_003294"
     CDS             4467..6968
                     /locus_tag="OE968_003294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HCP7220537.1"
                     /translation="MSSNKVVESYKITGMTCAACAKAVERVTKKMDGVYDQNVNIATE
                     KLKIEYDNSKVNFDDIKQVVEKAGYGIIKEESNKKIDMKIDGMTCAACAKAVERVVKK
                     LDGVESISVNIATDKANIDYDPSKVKLSQIKAAIEKAGYKPIEEVRNKVDVDEDKLRK
                     EREMKSLFVKFIVAIVFAVPLFYIAMGPMIIKPIGPWPLPEIINPMTNTFNYALIQLI
                     LVIPVMIAGYKFYINGFKSLFSLSPNMDSLVAIGTLAAFLYSLYTTLQIANGQIQGMH
                     HHQLYYESAGIIIALILLGKYLESKSKGKTSEAIKKLMGLQPKTAIVLVDGKEVETPI
                     EEVEIGDILLVKPGTKIPVDGVVIEGYTSVDESMLTGESIPVEKNVGSKVTGASINKN
                     GVIKFKAEKIGGDTALAQIIKLVEDAQGTKAPIAKLADTVSGYFVPIVIAIAVVASLL
                     WFLIGGKDIVFVLTIFISVLVIACPCALGLATPTAIMVGTGKGAENGILIKGGEALES
                     AHKVNTVIFDKTGTITEGKPKVTDIVLNNNVKEEYLIKIASSAEKGSEHPLGEAIVKY
                     GEEKNIKFEKVDNFKAIPGAGIQVTINDESILLGNRKLMNDNNIKLGDLEEKSNILAS
                     QGKTPMYIAVDGNLSGIIAVADVVKESSKKAIEILHDMGIKVAMVTGDNAKTANAIAN
                     QVGIDMVLAEVLPEDKSKEVEKLQNQGKFVAMVGDGINDAPALAKADIGIAIGSGTDV
                     AIESADIVLMKSDLIDVPTAIKLSHETIKNIKQNLFWAFGYNTIGIPVAAGILYVFGG
                     PLLNPMIAAAAMSLSSVSVVSNALRLKNFKAYKRD"
     gene            7128..7796
                     /locus_tag="OE968_003295"
     CDS             7128..7796
                     /locus_tag="OE968_003295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCP7220538.1"
                     /translation="MNSSILVIEDDSNIQELISEFLSAEGYQVDTANDGLEGIQKFKQ
                     GSYDLVILDIMMPNLDGYGVCKMIRKSSSVPIIFLTALNDEGDQLKGFDLECDDYITK
                     PFSFNLLIKRVEAILRRSNKTINDKFIVFEKLKLDLNTYIAEIDGEPIELTLKEFNIL
                     KALIEKYPQVITREGLLDSIWGYDYYGDTRIVDAHIKNIRKKISLPYIKTVKGIGYTL
                     EKDI"
     gene            7780..9057
                     /locus_tag="OE968_003296"
     CDS             7780..9057
                     /locus_tag="OE968_003296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HCP7220539.1"
                     /translation="MRRIFDKWEKLSIKYKLFSITTSLLIALALIIYLILYFLLPSYY
                     HEYKIESLQESLKSLVDSSIHFDTYTLEERLYYMAKDQNLAILLKDNQGKIVYGKNEV
                     VILRYSKYMINSLEDEYRTSIPIYTKDAKDGPYTLELVMPLQPIDEANEVIRKLMPYI
                     ISIAILIAIIGAYIYSIVITKPLINIIESEREQEYRRKDFVATISHELKTPITIISGQ
                     IEGMIYSVGKYKDRDTYLKKSYECTQELKDLVNEMIEVSKSEILEKDLKLVSINISEL
                     LNRLVKRQVFLIEEKHMKTILKIEENLEIKADQERITKAINNIINNAIKYSPEESELI
                     IRLYDKNKRISKKTSNQRVVLEIENTGVTIEKRYLEEIFNPFYRIEKSRSRKTGGSGL
                     GLYIVSQIFKSHGFDYSIKNKENSVVFTVEFKN"
     gene            9458..9679
                     /locus_tag="OE968_003297"
     CDS             9458..9679
                     /locus_tag="OE968_003297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220540.1"
                     /translation="MDRLKRDMKNMKEDLKEGVKKTAYVMKNTAEDLKDDAQGAMVNL
                     EMKKDEMMERYEQKKFSKELEKQMKNEMK"
BASE COUNT         3929 a         1114 c         1661 g         3153 t
ORIGIN      
        1 actacactat attacaaaaa aagtttacaa aactttaatt tgaaaaatgt aattatatgg
       61 tatatcatat aaatataagt aaatagtgct aatatttaaa ctattaatca taattggttc
      121 aacaaaagta tatagttaat aatgtttaat ttgaagaaat tgttagtgtg aaattacata
      181 tatattcaaa ttaaattcat aaatatttca cataataata gtatactgta aacaaaagga
      241 ggtattaaat atgggaatag tacttataac agcagcatta gttttggtta tgtatggact
      301 ttcaattcta tcatatatat cagaaagcaa tatattagaa gacactgtaa atgataacca
      361 ataaggtttt gaattatata aataagtgag aactgtaaat aaaagttaat ttttatttgc
      421 agttttttta tatatatgta aaataaagtt aattaataaa aaataatgtt ttgtttatag
      481 tatatatgga taataatagt aaagtataag aatgatgaga ataatatata agaaataata
      541 atataaagag aggtaaacgt tatggtagat atcattgtaa ttggtgctgg accagcaggt
      601 ttaacttcag caatttatgc tatgagagca gggttaagcg ttacagtatt tgaaaaaaat
      661 atttatggag gtcaagttgc aagtacctct gaggtagaaa attatccagc agttcaaaag
      721 atttctgggg tagaattttc taataatata tacaatcaag cagttgctca aggtgttgat
      781 attcagtttg atgaggttga agagataaat ttagagggaa aagtaaaggt tgtaaaaact
      841 tcttcaggtg aacataaagc aaaggctgtt attcttgcaa atggagttga aagacgtaaa
      901 ttaggttgtg caggggaaca agaatttaca ggtagaggag tatcttactg tgcaacatgt
      961 gatggagcct tttttaaaga taaagaagtt gctatagtag gtggaggaaa tactgcacta
     1021 gaagatgctt tatttttagc taataattgt acaaaagtgt atttaattca cagaagagat
     1081 agttttagag gtgaagaagt gttggagaaa tctgtgaaag caagagagaa tattgagata
     1141 ctttacagtc atggtgtaga aaaaatagaa ggagaaaaga ctgtatcgaa aatagaagta
     1201 aaaaacttaa agactgaaga aaaaagaact atagatgtta gtggtatttt tattgctata
     1261 ggtcttaaac ctaataataa aatgtttgaa aatgttcttg atttggatga aggtggatat
     1321 ataatttcag atgagtcttg tacaacatca gtagaaggtg tatatgtagc aggagatagt
     1381 agaactaagt ttttacgtca aataataaca gcagcatcag atggagctat tgcagccgtt
     1441 caagcagcta attatataaa tgttgaataa tataaatttc aaataaaaat agccatataa
     1501 actgaaataa tttttcagta ctatatggct attttgttaa ttagaggtaa atgtacgttt
     1561 tatttacctt gtctagattt gttatatctt aatctatcat gttcatttaa gaatcttttt
     1621 ctaagtctta tagaatcagg tgtaatttca actaattcat catcttctat aaactctaga
     1681 gcttcttcaa gagtaaatat tctaggagga gataatttta tagcatcatc tgaaccagaa
     1741 gcacgtacgt tactcatttt cttgttttta caaggattga ctaccatatc atcttttctg
     1801 gaattcatac caattatcat accttcgtaa acttctacac cagggtctac aaacattaca
     1861 gctctatcac ttaaggcatt aagagaatac cccatagtaa caccaggtcc ttgtgctatt
     1921 aaaacaccat ttcctcttga aggtatttct cctttaaatt cttcaaattt ttcaaatgaa
     1981 cgaactaaag taccttctcc acgagtagcg tttataaatt cacttcgata tcctaaaaga
     2041 ccacgagtag gtgctaagaa ctctattttt acatagtctc cttctattga catagactcc
     2101 atcatacctt ttctcatgtt taattcattt ataatagtac cagagtaaac ttcaggacag
     2161 tttacaacaa ctctttctat tggttccatt agttttccat cttctttatg cattaaaact
     2221 tcaggtttag aaacaccaac ttcataacct tcacgtctca tattttcaag tagtatagat
     2281 aagtgaagct ctccacgtcc agaaactttg tatccatcag tagtatcaag aggttcaact
     2341 ttaagaccaa catttacttc aagttctttt tcaagtctat ctttcaaatg tctagttgta
     2401 acgaattttc cactttttcc aacgaatgga gagtcgttta ctaagaagtt catagaaaga
     2461 gtaggctctt ctatttttat catttccata ggtagtggac tatctaaatc gcatatagtt
     2521 tcacctatag atatatcagg aataccagct ataacaacta tttctccact agtagcttca
     2581 tcaacttcaa cttgttttaa accttcatac acagaaagtt ttgatacttt tcctttagat
     2641 acaacagaat cttctctaca tatagcaact tgtgtattgt ttttaagagt acctttgtaa
     2701 attctaccta taccaagtct acctacataa tcatcatatg caagagctga tatttggaac
     2761 tgtagaggtt cattatcgta attaggataa gcttcaacgt gatttacaat agttttaaat
     2821 agaggagaaa ggtcttcact atcatcatcc atttcaagtt tagcaatacc ttgtttagca
     2881 ataccatata ttataggaaa ttcgcattgc tcatctgttg catttaagtc tacaaataaa
     2941 tcgaaaactt cattaactac ttcttccgct ctctggtctt ttttatcaat cttgtttata
     3001 aataatattg gttttaaacc gaactctaaa gatttttgta aaacgaatct agtttgaggc
     3061 attgggcctt cactagcatc aactaataga ataactgtgt caacagtttt cataacacgt
     3121 tcaacttcag aagaaaagtc actgtgtcct ggagtatcaa ctatgtttat tttgtaatct
     3181 tcatagttta ttgcacagtt ttttgaatat atagttatgc ctctttcttt ttcaaggtcg
     3241 ttactgtcca taacgcagtc tttaactact tcgttctttc taaaaacacc gctttgagaa
     3301 aggaaagcat caaccaatgt tgattttcca gcgtcaacgt gggctataac tgcgatattt
     3361 ataattttat gtttttgtga catttttgtt gctcccttcg attaaaataa cttattaatt
     3421 atagcacaat atattattag gtacaaggag gaatatatta aattgtatta atatagttta
     3481 aattggataa aactgttagt tttgcatctg aaaattattc tgtttaaaaa aattttttag
     3541 acaaataata accttaatag ataaaaagat taataaaaga gtaaaggatg atatatgttg
     3601 gaagtaacca aaataataat taaatatttt gcaagtgaaa gtgatacttt tgtaaaagaa
     3661 gaagtttgta attttgaaga acttcttaag tggtctcata aatttattga aggtaaaaag
     3721 atagaagatg ttttgtatat aaagtctaaa gaaaactata aagtaaatgt gattaagtct
     3781 ttagaaatta aggaattgga aatagtgaga aaacaacaga taccaccgta catgtagtat
     3841 taataatata taaaattaat atgtaatact cgcaatagga tataaatggt atatatggta
     3901 ataatttata ttaaaaaaac ttttataaag tttatatttg ggtataaaag tattaattag
     3961 acattaatta ggaggaactt aaatatgata agagtatgtc caaactgttc aaatgtggat
     4021 gtaaataagc taaaaacttt ggttggagaa gaaaatgtaa agactggttg tataggtcag
     4081 tgtagagcat ttaaaaaaga agctgttgga ataatagaca atgagcttga aataaaggaa
     4141 acagaagcag agttttttga agcatgtaaa gaataaattt taaataaaat ataaattata
     4201 ataaatagag catctaaatt gtataagcat taaacaattt agatgctcta tttttatata
     4261 tacatttaat tatgagtata cttttctatt aaatacaaat aaatataact aatacattta
     4321 tttattaaaa aaatattgat ttaatatacc tatagggggt ataatgaaaa tatagatttc
     4381 taaataagta atttatcaat attacatatc aaaataaaac gttacaaatt agctgaaaat
     4441 atattgaaag aaaggaagat tttattatga gttcaaataa agtggtagaa agttataaaa
     4501 ttacaggtat gacatgtgca gcttgtgcaa aggcagtaga gagagtaact aagaagatgg
     4561 atggagtata tgaccaaaat gtaaatatag ctactgaaaa acttaaaata gaatatgata
     4621 attctaaggt taattttgat gatataaagc aggttgtaga aaaagcagga tatggaatta
     4681 taaaggaaga aagtaataaa aaaattgata tgaaaattga tggaatgaca tgtgcagctt
     4741 gtgcaaaagc tgtagagaga gtggtaaaaa aattggatgg agtagaaagt attagtgtga
     4801 atattgcaac agataaagct aatatagact atgacccatc aaaagtaaaa ttatctcaaa
     4861 taaaagcagc tattgaaaaa gctggatata aaccaataga agaggtaaga aataaggttg
     4921 atgtggatga agataaattg agaaaagaaa gagaaatgaa gtctttattt gttaaattta
     4981 tagttgcaat agtatttgca gtacctctgt tttatatagc aatgggacct atgataataa
     5041 agcctatagg gccatggcct ttgccagaaa ttataaatcc tatgacaaat acttttaatt
     5101 atgcattaat tcagttaatt ttagtaatac cagtaatgat agctggttat aaattttata
     5161 taaatgggtt taaatcactt ttttctttaa gccctaatat ggattcttta gttgcaatag
     5221 gaacattagc cgcattttta tatagtctat atacgacact acaaatagcc aatggacaaa
     5281 ttcaaggtat gcaccatcat cagttgtatt atgaaagtgc aggaataata atagcactta
     5341 tcttacttgg taaatattta gaatcaaaat caaaaggaaa aacatcagaa gcaattaaaa
     5401 agcttatggg gctacaacct aaaactgcaa tagtgttagt tgatggtaaa gaagttgaaa
     5461 ctcctataga agaagtagag ataggagata tactattagt aaaaccagga actaaaatac
     5521 ccgtggatgg agttgtaata gaaggatata catcagttga tgaatcaatg cttacaggtg
     5581 aaagtatacc agtagaaaag aatgttggaa gtaaggtgac aggagctagt attaataaaa
     5641 atggtgttat taagtttaag gctgaaaaaa ttggtggaga tactgctctt gcccaaataa
     5701 taaagttagt tgaagatgca caaggtacaa aagcacctat tgctaaactt gccgatactg
     5761 tatctggata ttttgtacca atagtaattg caatagctgt agttgcatca ttattgtggt
     5821 ttttaatagg aggaaaagat atagtatttg tacttactat atttatatca gtacttgtaa
     5881 ttgcttgtcc ttgtgcatta ggattagcaa caccaactgc tataatggtt gggactggaa
     5941 agggcgcaga aaatggaatc ttgataaaag gtggagaggc actagaatct gcacataaag
     6001 taaatacagt gatatttgat aagacaggta ctataacaga aggaaagcca aaagtaacag
     6061 atatagtatt aaataataat gtaaaagaag aatatcttat caagattgct tcaagtgcag
     6121 aaaaaggttc agaacatcct cttggagaag caatagttaa gtatggagaa gagaagaata
     6181 taaaatttga aaaagttgat aattttaaag ctataccagg tgctggtata caagttacta
     6241 ttaatgatga aagtatatta cttggaaata gaaagcttat gaatgacaat aatataaagc
     6301 ttggagattt agaagaaaaa tcaaatatat tggcaagcca aggtaaaaca cctatgtata
     6361 tagctgtaga tggaaattta tcaggtataa tagcagttgc agatgtagtc aaagaaagta
     6421 gtaaaaaagc aatagaaata cttcatgata tgggaataaa agttgcaatg gtaactggag
     6481 ataatgcgaa aactgcaaat gctatagcaa atcaagtcgg tatagatatg gttttggcag
     6541 aggttttacc agaagataag tcaaaagaag ttgaaaaact acaaaatcaa ggaaagtttg
     6601 ttgcaatggt aggggatgga ataaatgatg ccccagctct tgcaaaagca gatataggga
     6661 tagcaatagg aagtggaacg gatgtagcca ttgaatctgc ggatatagta cttatgaaga
     6721 gtgatttaat tgatgttcca acagcaatta aacttagtca tgaaactata aaaaatataa
     6781 aacaaaacct attttgggca tttggatata atacaattgg tatacctgta gcagcaggaa
     6841 tattatatgt atttggagga cctttattaa acccaatgat tgcagcagca gcaatgagct
     6901 taagttcagt ttcagtcgta tcaaatgcac ttagacttaa aaacttcaag gcatataaga
     6961 gagattagat taataaatta aataaaatgt atccaaaaga gctatcttta aattaaaagg
     7021 attaatttac aaattaagat agctcttttt tcatgtaaaa ttcacaacaa taagataaaa
     7081 tataagtaat atacgaaatt ttaaataaaa tagaaaggat tgatagaatg aattcgtcaa
     7141 tacttgtaat tgaagatgat tcaaatatac aagagttaat atcagaattt ttaagtgcag
     7201 aaggttatca agttgataca gcaaatgatg ggttggaagg tatacaaaag tttaagcaag
     7261 gaagttatga tttagtaata ttagatataa tgatgccaaa cttagatggt tatggagttt
     7321 gtaaaatgat aagaaagtca tcaagcgttc caattatatt tttaactgct ttaaatgatg
     7381 aaggagacca acttaaaggg tttgacttag aatgtgatga ttatataaca aaaccatttt
     7441 catttaatct tcttataaaa agagtagaag caattttaag gcgaagtaac aagactataa
     7501 atgacaaatt tatagttttt gaaaaattaa aattagattt aaacacatat attgcagaga
     7561 tagatggaga acctatagaa cttacactaa aagagtttaa tatattaaaa gctttgatag
     7621 aaaagtatcc acaagttata actagggaag gtcttttgga tagtatatgg ggttatgact
     7681 attatggaga tactaggatt gttgatgcac atataaaaaa tataagaaaa aaaatatcat
     7741 taccatatat taaaactgta aaaggaatag gatatacact tgagaaggat atttgataag
     7801 tgggaaaagt taagtataaa gtataagtta ttttcaataa cgacatcatt attaatagca
     7861 ttagctttaa taatatatct aattttatat tttttattgc catcatatta tcatgagtat
     7921 aaaattgagt ctcttcaaga aagtttgaaa tctttagtag atagttcaat tcatttcgat
     7981 acatatactt tagaagaaag actttattat atggctaaag accaaaattt ggctatttta
     8041 ttaaaagata accaaggtaa aattgtatat ggtaagaatg aagtagttat tttaagatat
     8101 agtaagtaca tgattaatag tcttgaggat gagtatagaa cttctatacc tatatatact
     8161 aaagatgcaa aagatggtcc atatacttta gaactcgtta tgccattaca accaattgac
     8221 gaagcaaacg aagttataag aaaactaatg ccatacatca tatcaatagc aatattgata
     8281 gcgattattg gagcatatat atattcaatt gtaataacaa agcctcttat aaacataata
     8341 gagagtgaga gagaacagga atatagaagg aaggattttg ttgctacaat atcacatgaa
     8401 ctaaaaactc caataaccat aataagtggt caaattgaag gtatgattta tagtgtaggt
     8461 aagtataagg atagggatac ttatctgaaa aaatcgtatg agtgtacaca agaattaaaa
     8521 gatttagtaa atgaaatgat agaggtttca aaatcagaaa tacttgaaaa agatttgaaa
     8581 ttggtatcaa taaatataag tgaattatta aatagacttg taaagagaca agtattttta
     8641 atagaagaaa aacatatgaa aactatttta aaaatagaag aaaatttgga aattaaagca
     8701 gaccaagaga gaataactaa ggcaatcaat aatataataa ataatgccat aaaatattct
     8761 cctgaagaat cagagcttat aattagactc tatgataaaa ataaacgaat aagtaaaaag
     8821 acttctaatc aaagagtggt tttagaaatt gaaaatactg gtgtaactat cgagaaacgt
     8881 tatttagaag aaatatttaa tccattttat agaatagaaa aatctcgttc aagaaaaact
     8941 ggaggaagtg gacttggact ttatatagtc agccaaattt ttaaaagtca tgggtttgat
     9001 tatagcataa aaaacaaaga aaactctgta gtattcacag tagaatttaa aaattaatta
     9061 cttattataa agaatatata actttcaata atagttcatt ttaaaatcac aaaaaattca
     9121 taatgaaact gtattatata aatataaaga agcttaaaac cataaaatac accaactata
     9181 atgatgagat ttccttacat cctccatata agtcatcatt atagtaaccc aacaattaag
     9241 ttactatgaa tttaaaaaat aacaccgagc atataatcta tgcttagtgt tatttttatt
     9301 ttgaaataaa aaatatttaa tttattgaaa tgtatagatt tagatagttt aaactatatt
     9361 taagacttaa aaattataat tgatattaca aataaatata tgtactttgg gaaaaataaa
     9421 tataggaagt attatattta cagaggaggt agttttgatg gatagattaa aaagagatat
     9481 gaaaaatatg aaagaagatt taaaagaagg tgttaaaaag acagcttatg ttatgaaaaa
     9541 tacagctgaa gatttgaaag atgatgcaca aggtgctatg gtaaacttag aaatgaaaaa
     9601 agatgagatg atggaaagat atgaacaaaa gaaattttct aaagaattag agaagcaaat
     9661 gaagaatgaa atgaaataag cttttattta tgaataacaa attattgtat tcatataaaa
     9721 agtagccagt aatattaaat agtttattta aggaaataga ctttctaaaa ataactgtat
     9781 tagatttaga aagtctattt caaattagtt ttataaatag acataaggat aaagtagatg
     9841 ttatagaact agatttt
//
LOCUS       DAJMZY010000127         9795 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.129, whole genome shotgun sequence.
ACCESSION   DAJMZY010000127 DAJMZY010000000
VERSION     DAJMZY010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9795)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9795)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9795
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.129"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            complement(<1..2030)
                     /locus_tag="OE968_003298"
     CDS             complement(<1..2030)
                     /locus_tag="OE968_003298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF262 domain-containing protein"
                     /protein_id="HCP7220541.1"
                     /translation="MKAGEIEFLSYLEGSNKSFVVPVYQRNYNWKKEQCKRLFDDLED
                     IIDSGFRTHFLGSVVSIYSMGKEYLIIDGQQRVTTVSILLIAMCQIIKEFGESKGIIT
                     TEEQIKECYLINKHSRDKDGKIKLKPIAEDRKAYYELFEEEMNTDRNSNIVSNYLYFY
                     NRIKEDNISIDDLFDAIQKLTIVEIELKNGEDDPQLIFESLNSTGLDLSEADRVRNFV
                     LMGRSSKLQEEFYNNYWYKIEKNTSSNVSSFIRDYLTIKERSIPNKNKVYFSFKRYVS
                     DNGIDIEILLKDLLKFSNYYREISYSCTDDNDVNKVLKRINKLEIFVSYPFILELFDD
                     YNEGIINKKVLVESLNLVECFILRRIVCDVPPNALNKVFMNLGREIKKFSDYKENYSN
                     ILRYIFINKKSSQRFPTDSEFSNAFETKDIYNTKSKNKLYILERLENYNNKEIVDLEN
                     LINNNMLNIEHIMPQTLTNKWKESLGDNYKEIHDKYLHTIGNLTLTGYNSKLSNKTFE
                     EKKEMEDGFKDSRLYLNKYISSIDKWNEEEIKNRTKILLDRAVEIWKYPSVTYEPPSN
                     SENIFTLEDDDVNFTNESIVSFSILGESYKAKNWTEFYEQVALTLYDLDSVRFNSIVD
                     KTYKRDFIDNIKSRDAYKLRKGIKISENIYLETNLNTEAKLNIIRFLLNEFD"
     gene            complement(2411..5746)
                     /locus_tag="OE968_003299"
     CDS             complement(2411..5746)
                     /locus_tag="OE968_003299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HCP7220542.1"
                     /translation="MGNFDFLQKKKNFNSFNTACLEAEKSILVSPSTCATITRRALEL
                     AVKWLYANDSDLVLPYQDNLSTLIHNNSFIELIDYDMLPLLKYIVKLGNLSVHTSANI
                     ERGEAILSLNNLHQFVSWIDYCYSDEYTAEDFNEDLLLHGEEKRTRPDELKNLYERLS
                     SKDKKLEEVIKENEELRKSLTEKRKVNTVNYDFKIDEVSEFETRKRYINIELKLAGWE
                     FGKDIWEEIEVQGMPNESGVGYVDYVLYGENGKPLAVVEAKRTSKDPKIGQQQAKLYA
                     DCLEKRYSQRPVIFLTNGFDMYIWDDYSDRKVYGFYKKSELQLMIDRRKSKKSLSSVT
                     INDEISNRYYQKEAIRAVCEALENKQRKTLLVCATGTGKTRIAISIVDVLSRHNWIKN
                     ILFLADRKALVKQAKKSFTKLLPNLALCNLLDSKDSPEDARMIFSTYPTMMNAIDDTK
                     SKDGKRLFTPGHFDLIIIDESHRSIYKKYKSIFDYFDSYLMGLTATPKDEIDKNTYSV
                     FDMENGVPTYAYEYNKAVEDGYLVDYTSIEFKTKIMEDGIKYDELSDEEKEEYENTFN
                     DDESIGDEIGNNAVNEWLFNSDTIDLVLNKLMTEGLKIEGEEKIGKTIIFAKNTKHAR
                     AIVERFNKLYPKYGGNFVKAVDYSINYVDSIIDDFSDKNKLPQIAVSVDMLDTGIDIP
                     EILNLVFFKKVRSKTKFWQMIGRGTRLCPDLLGVDMDKERFLIFDFCNNFEFFKFNPK
                     GFEGNKTETLTEKLFNIKVSMVKELQDIKYIEGEYAELRKELLEELITSVKALNEDSY
                     IVRMNLSYVHKYKNENVWSNIGAVAQNEIREYISPLITSYSDDELAKRFDVVMYNIQL
                     AYLQNNNASKGIRHVMATAEKLSKLGTIPQIQQQKYTIEKAMTEDFWEDSDIFEVEEV
                     RISLRELIKYLEKSSQKIYYTSFEDMIVAEDRNDSVYNANNLKNYKKKVEYYLNSHKD
                     ELAIFKLRNNKKITKQDVETLEEILLKQLGNCDDYKKEFGDTPVSQLVRRLVGLDREA
                     ANEAFSEFLNNKSFNTKQIHFVKLIVDYVVKNGFIEDNKVLMEDPFRTVGSIIDLFEN
                     HIEERNKLIKTINKIKENASEIG"
     gene            complement(5796..6224)
                     /locus_tag="OE968_003300"
     CDS             complement(5796..6224)
                     /locus_tag="OE968_003300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220543.1"
                     /translation="MVIRNKLSWNSIEEVNRDFGSCLYDLQNFKILYDKEEMPELWAR
                     YIKEGFKSYMVSFLELTKAMLYYKSIDLNIKSKNFYDYLLACEYHNLLPKNSSIVIET
                     LRKLRNDDSHGYDIPQFEDMYELFTENEEVFVSIRNSCKK"
     gene            complement(6214..6594)
                     /locus_tag="OE968_003301"
     CDS             complement(6214..6594)
                     /locus_tag="OE968_003301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HCP7220544.1"
                     /translation="MRNIPNEIKNSIINVFPKENTLAIIIFGSYGTDKHTSESDIDIA
                     WIPIKKVPITELATKTEALRNILDIDVDLKIVTDNYTIALKKAILEGEVIYKSKDFKD
                     YINKFYFENSDVIDILDWRDMYGN"
     gene            complement(6627..6935)
                     /locus_tag="OE968_003302"
     CDS             complement(6627..6935)
                     /locus_tag="OE968_003302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220545.1"
                     /translation="MNQIELDLYHNMVNIYKEADLQCNYKPTRFLQLINNKGALLAAK
                     ELINKEGATEGFTRLWECKRLDLSLEVLVLKEKYKELFTDEEREICINRLKDYGYKFN
                     "
     gene            complement(6980..8140)
                     /locus_tag="OE968_003303"
     CDS             complement(6980..8140)
                     /locus_tag="OE968_003303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HCP7220546.1"
                     /translation="MEYRLNEVFEFIRNGASIKQFDTKFGYPITRIETIANSYIDTNK
                     MGYADIKELGKLEDYLLKNGDILMSHINSEKHLGKSAIYEDINKKIIHGMNLLCLRPD
                     KEVCYPKYLNYFFNSNEFRRQLPRIIKKSVNQASFSVNDLKNLKVDLPEMEAQKDISK
                     VLDKAQELIDKRKEQIEALDELVKSRFIEMFGNFKEQKFVLLKDCTNFIDYRGKTPIL
                     SENGIRIINAKSVGNGVFKYINEYISENTYNSWMKRGFPVAGDVLFVTEGHTFGNVCR
                     IPKDLKKFAMGQRIITIQGDKKILNNAFLAQYMQTKAFRVEIDKYKTGSSAQGIRSKE
                     LQKILIPVPSIELQNKFEEFVNQVDKLKVGIKTSLKELEDNFNSLMQKAFKG"
     gene            complement(8144..9607)
                     /locus_tag="OE968_003304"
     CDS             complement(8144..9607)
                     /locus_tag="OE968_003304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HCP7220547.1"
                     /translation="MITGELRSKVDKIWETFWTGGLTNPLEVIEQFTYLLFIKGLDEV
                     ETKNEAEATLLGVSFEKIFDDEHQHLRWSKFSNEGNSEKMYEIVQNEVFPFIKKLHGN
                     KESAYAKYMGDAIFKIPTPLMLSKIVDGISNLELSKDRDTKGDLYEYLLSKVATAGTN
                     GQFRTPRHIIDMIVRLIKPTPEDIIVDPAAGSAGFLVSSQQYLRDNHSSLFLVQGLKE
                     HFNNGMFYGFDMDRTMLRIGAMNMMLHGVDNPNIEYKDSLSEVNTDKDKFTLVLANPP
                     FKGSLDYEAVSADLLKVTKTKKTELLFLALFLRVLKIGGRCACIVPDGVLFGSTGGHK
                     SIRKEIVDNHKLEAIISMPSGVFKPYAGVSTAIMIFTKTGTGGTDKVWFYDMKADGYS
                     LDDKRNEIKDSDIEDIIKRFDNLDGEVDRKRTEQSFFVDVEEIRENGYDLSINKYKEV
                     VYEEVVYDAPSVIIGRVRELEKEIVDGLEELERMLEV"
BASE COUNT         3061 a         1807 c          877 g         4050 t
ORIGIN      
        1 atatcaaact cattaagtaa aaatctaatt atatttaatt tagcctctgt atttaaattt
       61 gtttctaaat atatattttc tgatatttta ataccttttc ttaatttata tgcatctcta
      121 gacttaatat tatctataaa atctctttta taagtcttgt ctacaatact gttaaacctt
      181 acagaatcca aatcatataa agtaagagca acttgttcat aaaattctgt ccaattttta
      241 gccttatatg actctcctaa tatactaaat gatactatac tttcatttgt aaaattaaca
      301 tcatcatcct ctaacgtaaa tatattttca ctgttacttg gaggttcata tgtaacactt
      361 ggatatttcc aaatttctac agctctatct agtaatatct tagttctatt ttttatttct
      421 tcttcattcc atttatctat agatgaaata tatttattta gataaagcct actatcttta
      481 aatccatctt ccatttcttt cttttcttca aatgttttat tacttagttt tgaattatat
      541 cctgtcaaag ttaaatttcc aattgtatgt aaatatttat catgtatctc cttatagtta
      601 tctcctagtg attccttcca tttatttgtt aatgtctgtg gcattatatg ctctatattt
      661 agcatattat tattgattaa attttctaaa tcaacaattt ctttattatt ataattctct
      721 aacctctcaa gtatatataa cttattcttt gacttagtat tatatatatc tttagtttca
      781 aaagcatttg aaaattcact gtcagtagga aatctttgag atgatttctt atttataaaa
      841 atatatctta atatattaga atagttttct ttataatcac taaatttttt aatttccctt
      901 cctaagttca taaatacttt attcagtgca ttaggaggta catcacatac tattcttctt
      961 aatataaaac attctactaa attaagggat tctacaagta cttttttatt tattatacct
     1021 tcattataat catcaaataa ttctaatata aacggatatg atacaaatat ttcaagtttg
     1081 tttatccttt tcaaaacttt gtttacatca ttatcatcag tacatgaata agatatctct
     1141 ctataatagt tagaaaattt aagtaaatct tttaataaaa tttctatatc tataccatta
     1201 tctgatacat accttttaaa actaaaatat actttatttt tattcggtat acttctctcc
     1261 tttatagtca aatagtctct tataaaacta cttacgttgc tacttgtatt tttttcaatt
     1321 ttataccaat aattattata aaattcctct tgtaacttag agcttctacc cattaacaca
     1381 aagtttctta ctctatcagc ttcacttaaa tctaagccag ttgaatttag actttcaaag
     1441 attaattgag ggtcatcttc accatttttt aactctattt ctactatagt taatttctgt
     1501 atagcatcaa acaaatcatc tattgatata ttatcttctt ttattctatt ataaaaatat
     1561 aaataatttg aaactatatt agaatttcta tctgtattca tttcttcttc aaatagttca
     1621 tagtacgctt ttctatcttc tgctattggt tttaacttta tttttccatc tttatctctt
     1681 gagtgcttgt ttataagata acactcctta atctgttctt ctgttgtaat aattcctttt
     1741 gattccccaa actcttttat tatttgacac atggcaatca ataatattga cacagtagtc
     1801 actctttgtt gtccatctat tattaaatat tcttttccca tactatatat agatacaact
     1861 gaccctaaga aatgagttct aaatccagaa tctattatat cctctaaatc atcaaacaat
     1921 cttttacatt gttctttctt ccagttataa tttctttgat atacaggtac tacaaaactt
     1981 ttgtttgacc cctctaaata actaagaaat tcaatttctc ctgctttcat attaactccc
     2041 cctataagtt aaataaattc cattcataac tccatgtatc tatatattat atcaaaattt
     2101 tgactcataa atgtatatga aagccttatt atataccttt ttatacctgt ttttatttta
     2161 ttaaagtaaa tacatgatta ttctataaaa tatacaaata cttaatttta aaaattatta
     2221 tttaatcttc ttcatgagta attcatagtt atttatcaat taaaaagaga tattgcataa
     2281 ttattcaata cctctctttg tatatttaca ttatccatat ctagttatct atttcaaccc
     2341 aatattagac tacctactaa taaatttatt ctctacatca ttaacaataa ttttgcacta
     2401 aataacatca ttagcctatc tctgatgcat tttctttaat tttatttata gttttaatca
     2461 atttatttct ctcttcaata tgattttcaa ataaatcaat tatacttcca acagttctaa
     2521 atgggtcttc catcaacact ttgttatcct ctataaatcc attcttgact acataatcga
     2581 ctataagttt aacaaaatgt atttgcttag tattaaagct cttattattt aaaaactctg
     2641 aaaaagcttc atttgcagct tctctatcca atcccactag tcttctcact aattggctta
     2701 ctggagtatc tccaaactcc ttcttataat catcacaatt acctaactgt tttaagagta
     2761 tttcctccaa cgtttcaaca tcttgctttg ttatcttttt attatttctt aatttaaata
     2821 ttgctaattc atctttatgg ctatttaaat aatactctac cttcttttta taattcttaa
     2881 gattgtttgc attatataca gaatcatttc tatcttctgc tacaatcata tcttcaaaac
     2941 ttgtataata tatcttttga ctagactttt caagatactt aataagctct cttaatgata
     3001 tacgtacttc ttctacctca aatatatctg aatcttccca aaaatcctct gtcattgctt
     3061 tttcaatagt atatttttgt tgctgaatct gtggtatagt cccaagtttt gaaagttttt
     3121 ctgctgtagc cattacatgc cttatacctt tacttgcatt attattttgt aagtatgcaa
     3181 gttgtatatt atacataact acatcaaatc ttttagccaa ttcatcatca ctatatgaag
     3241 ttatgagtgg tgatatatat tctcttatct cattttgtgc tactgctcca atattgctcc
     3301 aaacattttc atttttatac ttatgtacat aacttaaatt catcctaact atataactat
     3361 cctcatttaa agcttttaca gaagttataa gttcttctaa caattctttt ctaagttctg
     3421 catactcacc ttctatatat ttaatatctt gaagttcttt aaccatactt acctttatat
     3481 taaataattt ttcagtaagt gtttctgttt tatttccctc aaatccttta ggattaaatt
     3541 taaaaaattc aaaattatta caaaaatcaa atattaagaa tctttcctta tccatatcaa
     3601 cacctaataa atctggacat aatctagttc ctctacctat catttgccaa aacttagtct
     3661 tacttctcac tttcttgaaa aaaacaagat ttagtatttc aggtatgtca attcctgtat
     3721 caagcatatc tactgaaact gctatttgag gtaatttatt cttatcagaa aaatcatcta
     3781 ttatagaatc tacataattt atactatagt caactgcttt tacaaagttc ccaccatact
     3841 ttggatacag tttattaaat ctttcaacta ttgccctagc atgctttgta ttctttgcaa
     3901 aaattatagt cttaccaatc ttttcttctc cttctatttt caacccctct gtcattagct
     3961 tatttaaaac taaatctatt gtgtcagaat taaatagcca ctcatttact gcattattcc
     4021 ctatttcgtc tccaatactc tcatcatcat taaatgtatt ttcatattct tccttctctt
     4081 catcagaaag ctcatcatac ttaattccat cttccataat cttagtctta aactcaatac
     4141 tagtataatc tactaaatat ccatcctcga ctgccttatt atactcataa gcatatgtag
     4201 gtactccatt ttccatgtca aaaactgaat aagtattttt atctatctca tcctttggtg
     4261 tagcagtaag acccattaag taagaatcaa aataatcaaa gattgactta tactttttat
     4321 aaatacttct atgcgattca tctattataa ttaaatcaaa atgaccaggt gtaaacaatc
     4381 tctttccatc cttagacttc gtatcatcaa ttgcattcat cattgttgga tatgtagaaa
     4441 atatcatcct agcatcttct gggctgtctt tgctatccaa taaattacat aacgccaagt
     4501 taggtaatag cttagtaaaa ctttttttag cttgctttac caatgctttt ctatctgcta
     4561 gaaataatat atttttaatc caattatgtc ttgaaagtac atcaactata gatatagcaa
     4621 ttcttgtttt tcctgtacca gtagcacata ccaaaagagt tttgcgttgc ttattttcaa
     4681 gagcctcaca tacagcccta atagcttctt tttgataata tctattggat atttcatcat
     4741 ttattgttac agaacttaaa gacttcttac tctttcttct atctatcata agttgtaatt
     4801 ctgatttttt ataaaatcca taaactttcc tatctgaata gtcatcccaa atatacatat
     4861 caaaaccatt agtcaaaaat attaccggtc tttgactata tctcttttcc aaacaatctg
     4921 catataattt agcttgttgt tgaccaattt tcgggtcttt actcgttctt ttcgcctcaa
     4981 ctactgctaa tggcttacca ttttcaccat aaagaacata atctacatat cccacaccac
     5041 tttcattagg cataccttgt acttctattt cttcccatat atcttttcca aattcccaac
     5101 ctgcaagctt taattctata tttatatatc tttttcttgt ctcaaattcg cttacttcgt
     5161 ctatcttgaa atcatagttt acagtattaa cttttctctt ttcagttagt gactttctta
     5221 attcctcatt ttcttttatt acttcttcaa gctttttatc ttttgaactt aatctctcat
     5281 aaagattttt aagttcgtct ggtctcgtcc ttttctcttc cccatgaagt aataaatctt
     5341 cattaaagtc ttctgctgta tattcatctg aataacaata gtctatccaa ctaacaaatt
     5401 gatgcaaatt gttaagtgaa agtattgctt ctcctctctc tatgttcgca ctagtatgta
     5461 cagataaatt acctaattta actatatatt ttaataaagg taacatatca tagtctataa
     5521 gttctataaa actattatta tgaatcaacg tactaagatt atcttgataa ggcaatacta
     5581 aatcactatc attagcatat agccatttta ctgcaagctc taaagctctt cttgttatag
     5641 ttgcacaagt agatgggcta actagtatac ttttttctgc ttctaagcaa gcagtattaa
     5701 aactattgaa atttttcttc ttttgtaaaa aatcaaaatt acccaaggct tttatccccc
     5761 ttttgtccct tagttaaaat aaatctctct aaaaactatt tcttacagct gtttcttata
     5821 ctaacaaata cttcttcatt ttctgtaaac aattcgtaca tatcttcaaa ctgtggtata
     5881 tcatatccat gagaatcatc atttctcaat tttctaagtg tttctataac tatagaagaa
     5941 tttttaggta ataaattgtg atactcacaa gctaaaaggt agtcataaaa gtttttagat
     6001 tttatgttta aatcaattga tttataatac aacattgctt ttgttaattc tagaaatgat
     6061 accatatagc ttttaaagcc ttcttttatg tatctagccc ataactcagg catttcttcc
     6121 ttatcatata agattttgaa gttttgcagg tcatacaagc aagaaccaaa atccctattt
     6181 acttcttcta ttgagttcca agataatttg tttctaatta ccatacatgt ccctccaatc
     6241 taagatatct attacatcac tgttttcaaa atagaattta tttatataat ccttaaaatc
     6301 tttagattta taaataactt caccttctaa aatagctttt ttaagtgcta ttgtataatt
     6361 atctgtaaca atttttaggt ctacatcaat gtctaatata tttcttagag cttctgtctt
     6421 agttgcaagt tctgtaattg gtactttttt gatgggaatc caagctatgt ctatatcact
     6481 ttctgatgta tgtttatctg ttccataact accaaatatt atgattgcta gagtattttc
     6541 ttttggaaat acatttatta ttgagttttt aatctcattt ggtatatttc tcatttaatc
     6601 acctcttgtt tattaggtaa tattgcttaa ttgaatttat atccataatc ttttaatcta
     6661 tttatacata tttctctttc ttcatcagta aacaactctt tatacttttc ttttaatact
     6721 aatacttcta atgataaatc taatctctta cactcccata gccttgtaaa tccttcagta
     6781 gctccttctt tattgattaa ttctttagca gctaataagg ctcctttgtt atttatcagt
     6841 tgtaaaaatc ttgttggctt atagttacat tgtaaatcag cttctttata gatatttacc
     6901 atgttatggt ataaatctag ctctatttga ttcatagatt ttattccccc attttaataa
     6961 ttgtatttta gttgaataac tatcctttaa aagctttttg cattaatgag ttaaagttgt
     7021 cttctagttc ttttagactt gtttttattc ctactttcaa tttgtctact tgattaacaa
     7081 actcttcaaa cttattttga agttctattg atggtactgg tattaatatt ttttgaagtt
     7141 ctttgcttct aattccttgt gcagagctac cagttttata tttatctatt tctaccctaa
     7201 aagcttttgt ttgcatatat tgtgctaaaa aagcattatt taaaattttt ttatctccct
     7261 gaattgttat aatcctttga cccatagcaa acttttttaa atcctttggt atcctacata
     7321 catttccaaa tgtatgacct tctgtaacaa aaagtacatc tccagctact ggaaaacctc
     7381 ttttcatcca agaattatag gtgttttcag atatatattc attaatatat ttaaatacac
     7441 cattccctac agattttgca tttattattc taattccatt ctctgaaaga attggagttt
     7501 taccacgata atcaataaaa tttgtacaat ctttcaataa tacaaacttt tgttccttaa
     7561 aatttccaaa catttcaata aatcttgatt taactaattc atccaatgct tctatttgct
     7621 cttttctttt atctattaac tcttgagctt tatctaaaac ttttgatata tctttttgag
     7681 cttccatttc aggtaaatct acttttaaat tttttaaatc attaactgaa aaacttgctt
     7741 gattaactga tttttttatt atccttggta actgtcttct aaattcatta ctattaaaaa
     7801 aataatttaa atactttgga taacaaactt ctttatctgg tcgtaaacat aaaagattca
     7861 ttccatgtat aattttttta tttatatctt catatattgc acttttccct aaatgttttt
     7921 cactattaat atgtgacatt agtatatctc catttttcaa taaatagtct tctaattttc
     7981 ctaactcttt tatgtcagca tatcccattt tattagtatc aatataagag tttgctatag
     8041 tttctattct tgtaattgga tatccaaatt ttgtatcaaa ttgtttaata ctagccccat
     8101 ttctaataaa ttcaaaaact tcattcaatc tatattccat actctacacc tcaagcattc
     8161 tttctaattc ctctaatcca tctacgattt ccttctctaa ctccctaact ctacctataa
     8221 taacactagg agcatcataa actacttcct catacactac ctctttatac ttattaatag
     8281 ataaatcata cccattctct cttatctctt ccacatcaac aaaaaagctt tgctctgttc
     8341 tttttctatc tacttcacca tcaagattat caaatctctt aataatatcc tctatatcac
     8401 tatcctttat ctcatttctc ttatcatcca aagaataacc atcagctttc atatcataga
     8461 accatacctt atcagttcca cctgttcctg ttttagtaaa tatcattata gctgtagata
     8521 ctcctgcata aggcttaaac actccacttg gcattgatat tatagcttcc aatttatgat
     8581 tatcaactat ttcttttctt atcgatttat gtccacctgt tgaaccaaac aatactccat
     8641 ctggcactat acatgcgcat cttccaccaa tttttaaaac tcttaaaaaa agtgccaaga
     8701 ataataactc tgttttcttt gtcttagtca cttttaataa atctgctgac actgcttcat
     8761 aatctaaact tcccttaaaa ggaggatttg ctaacaccaa tgtaaactta tctttatctg
     8821 tattaacctc cgataaagaa tccttatact ctatattagg attgtcaacg ccatgcaaca
     8881 tcatattcat agcacctatt ctaagcatag ttctatccat atcaaatcca tagaacatac
     8941 cattattaaa atgctccttc agcccttgca ctaagaaaag acttgaatga ttatccctta
     9001 agtattgttg tgatgatact aaaaaacctg ccgaacctgc tgccgggtct actataatat
     9061 cttctggtgt tggtttaata agtcttacta tcatatctat tatgtgtctt ggagtcctaa
     9121 attgaccatt agtacctgct gtagccactt tggataataa atactcatac aaatctccct
     9181 ttgtatctct atccttactt aattctaaat tactaatacc atcaactatt ttagataaca
     9241 taagaggcgt aggaatttta aatattgcat ctcccatgta ctttgcataa gctgattctt
     9301 tatttccatg taattttttt atgaaaggga acacttcatt ttgtactatt tcatacattt
     9361 tttctgaatt tccttcatta gaaaacttac tccaccttaa atgttgatgt tcatcatcaa
     9421 atatcttttc aaaagaaaca cccaaaagag ttgcttctgc ttcatttttt gtttctactt
     9481 catccaatcc tttaataaat aaaagatatg taaattgttc tataacttct aatggattag
     9541 ttaatccacc agtccaaaaa gtctcccaaa tcttgtccac tttactcctt aattctcctg
     9601 taatcatata tgactttccc tccagtgttc ataaaataat ttaaatatat attttagtcg
     9661 tacgccttaa tagttagtgt cttatgttaa atccaagttt ttactacaca attattaaat
     9721 tatttttcct atttacatat tttagctaaa aaactaatgc aatactctta ttttatgatt
     9781 attatatata ccata
//
LOCUS       DAJMZY010000128         9674 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.130, whole genome shotgun sequence.
ACCESSION   DAJMZY010000128 DAJMZY010000000
VERSION     DAJMZY010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9674)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9674)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9674
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.130"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            complement(<1..581)
                     /locus_tag="OE968_003305"
     CDS             complement(<1..581)
                     /locus_tag="OE968_003305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CatB-related O-acetyltransferase"
                     /protein_id="HCP7220548.1"
                     /translation="MTIPSSNKVYPRSNDYQTVYLKNVITRENIEVGDYTIYNDFYND
                     PRDFEKNNVLYHYPINNDKLIIGKFCSIACNAKFLMTSGNHSMKSKSTYTFPIFYEEW
                     KLDINHITDAWDNKGNIIIGNDVWIGYDSIIMSGVNIGDGAIIGTRAVVTNDVPPYSI
                     VGGVPAKIIKKRFNNDTISKLLEIKWWDWPYKK"
     gene            complement(653..1006)
                     /locus_tag="OE968_003306"
     CDS             complement(653..1006)
                     /locus_tag="OE968_003306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase DNA-binding domain-containing protein"
                     /protein_id="HCP7220549.1"
                     /translation="MSTEKRRDNKDRILRTGESQRKDGRYAYKYVYSFGKPQFVYSWK
                     LVPTDKPPKGKRDDISLRDKEKAIQNDLDDSIDTIGKKMTVCQLYAKKNGLRKNIRLN
                     TKKGRHYLMKILNKE"
     gene            complement(1084..1287)
                     /locus_tag="OE968_003307"
     CDS             complement(1084..1287)
                     /locus_tag="OE968_003307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HCP7220550.1"
                     /translation="MNNTDVPIWEKYTLTIEEASKYFRIGEKKLRKLADENLDSGWVI
                     MNSNRIQIKRKQFEKIVDTLDFI"
     gene            complement(1677..1907)
                     /locus_tag="OE968_003308"
     CDS             complement(1677..1907)
                     /locus_tag="OE968_003308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCP7220551.1"
                     /translation="MKPTKEVLPFTIILLAVHGDVNAINGILKHFEHYIIRLSQKTLF
                     DEYGNPYIHVEEETKRMLGTKLITAILRFNLS"
     gene            complement(1909..2316)
                     /locus_tag="OE968_003309"
     CDS             complement(1909..2316)
                     /locus_tag="OE968_003309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HCP7220552.1"
                     /translation="MVDEKTIEHQFDSFCKTVLRNYARDIYDENKRRNDYLVSLESLS
                     LAELSKLSILDDYDSNYICMVSYDYNIRIEDVLMAQAIGKLTKRKQDIILLSFFLNMT
                     NADIATLMDLAENTIHYHKTNALKELKELMEEH"
     gene            complement(2676..3125)
                     /locus_tag="OE968_003310"
     CDS             complement(2676..3125)
                     /locus_tag="OE968_003310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCP7220553.1"
                     /translation="MELIEWNYAYITDLVEFANDKEIAKNLRDNFPHPYREQNARDFV
                     SFCLATPDVKQLSYAIFYQERAIGSISLTFEEDTSINKNAELGYWLARNYWGKGIATN
                     AVKEICKIAFEKYNLNKIHANVYSYNRGSSKVLEKCGFKIEEYCHNS"
     gene            complement(3139..4065)
                     /locus_tag="OE968_003311"
     CDS             complement(3139..4065)
                     /locus_tag="OE968_003311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220554.1"
                     /translation="MSDILSRITNKIGDKNIVDKLSALSKSDLNSLLLEVFDRQANTL
                     TATDILKSYQLNRFTIPSGIDPEEIHALESKLLRKAFNMDIKTIMLSPSAPLGSCSVF
                     GSVDQYNVVSALRGTETLADPSNMLAIIIADKLKRKEENNTIPIHMATTARVIRAQNF
                     VGKGLYSHFGLYCMVSSGIDTGSYTCEKMLLEKHLNYYKDILSEIENVRFSIILRKRN
                     GYKDNDGFFDRMVETIKLIFPNIELSIHNDDVDNNYYKGINFKLSVKQGNETVEIVDG
                     GFVDWTYQMLGNKKERCLISGIGLERFLVAVS"
     gene            complement(4190..4594)
                     /locus_tag="OE968_003312"
                     /pseudo
     CDS             complement(4190..4594)
                     /locus_tag="OE968_003312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433844.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="oxalate:formate antiporter"
     gene            complement(4744..5364)
                     /locus_tag="OE968_003313"
     CDS             complement(4744..5364)
                     /locus_tag="OE968_003313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HCP7220555.1"
                     /translation="MHLIDFMNEDIKKKLVKKTYKKKETILFAEQENEYVILMIDGIA
                     EAFILNVKGNISTIHLYRSGSFFGEMEQFNDGKKPVEIVAFTDCNVYKLHRDDFLNWL
                     RGDFEATKFLIREISSKLVVNAELIEELSSLSVKERLLRCISLHYYRSELNLLTKKQL
                     ASEVNAPIRSINRAINECVQEHLIAYENKRFSVINQREVLKNLPTT"
     gene            complement(5463..6731)
                     /locus_tag="OE968_003314"
                     /pseudo
     CDS             complement(5463..6731)
                     /locus_tag="OE968_003314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331151.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
     gene            6823..7638
                     /locus_tag="OE968_003315"
     CDS             6823..7638
                     /locus_tag="OE968_003315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage integrase family protein"
                     /protein_id="HCP7220556.1"
                     /translation="MVKLSDAKSWAIRMSEDGCAYKSIDNYKRSLKASFFMAIQDDCI
                     RKNPFNFQLSDVLEDTTEPKIALTPEQEMGLLSFMESDKTYCKYYDDVVILLETGLRI
                     SELCGLTLELDMKNKAIMVDHQLLSDTKIGYYVEVPKTTQGKREIPMTERAYQSFERI
                     VERRKNAKAEPIIVDGYQNFLFLKQDGLPKQATHYQSMLRALVKKYNKTHEDKLPKIT
                     PHTFRHTLCTNMANKGMSPNILQYIMGHKNITMTLGYYAHGSFSSSRAEMERL"
     gene            8310..9077
                     /locus_tag="OE968_003316"
     CDS             8310..9077
                     /locus_tag="OE968_003316"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HCP7220557.1"
                     /translation="MKRKVQVKNITIGEGRPKICVPIIGKNKKDIIKEAKELKDACLD
                     IIEWRVDFFENVENIKEVKEVLYELRSYIHDIPLLFTFRSVVEGGEKLISRDYYTTLN
                     KEISNTGLVDLIDVELFMGDEVIDEVVNFAHKKEVKVIISNHDFNKTPKKEEIVSRLC
                     RMQELGADLPKIAVMPQNEKDVLVLLEATNEMFKIYADRPIITMSMSGMGVISRLCGE
                     IFGSALTFGAAKSVSAPGQISFKELNSVLNLLHKSIN"
     gene            complement(9405..>9674)
                     /locus_tag="OE968_003317"
     CDS             complement(9405..>9674)
                     /locus_tag="OE968_003317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220558.1"
                     /translation="KLDKESINKIYNRKIKIEREVNIFEDEDVIINKKVLKFPKSWTK
                     NMQKYWLSENKYPIHSTVIDDDRYKCCNVQYTKNRVIILYYIYNH"
BASE COUNT         3208 a         1559 c         1469 g         3438 t
ORIGIN      
        1 atttttttat atggccaatc ccaccattta atttctaata attttgaaat tgtatcatta
       61 ttaaatctct tttttataat ttttgcaggt actcctccaa caatagaata cggtggaacg
      121 tcattagtaa ctactgctct tgttccaata attgcaccat caccaatatt tacacctgac
      181 ataattatag aatcataacc tatccacaca tcatttccaa ttataatgtt acccttattg
      241 tcccaagcgt ccgttatatg gttgatatcg agtttccatt cttcataaaa gatgggaaaa
      301 gtatatgtgg attttgattt cattgagtga tttccactag tcattagaaa ttttgcatta
      361 catgctattg agcaaaactt accaattatt aatttatcat tgtttatagg gtaatgatac
      421 aatacattgt ttttctcaaa atctcttggg tcattataaa agtcattata tattgtgtaa
      481 tctccaactt ctatattttc ccttgttatt acatttttaa gatatacagt ttgataatca
      541 ttacttcttg gatatacctt atttgaactt ggaatagtca tatttaaatc tctcctttaa
      601 tatatattat gtttttgact attccactac tacaatacat ctcttcacag aatcactcct
      661 tgttaagaat cttcataaga taatggcgtc cttttttagt gttaagtcgg atattctttc
      721 ttagtccatt ctttttagcg tataactgac aaactgtcat tttcttacca atagtgtcaa
      781 tgctatcatc aaggtcattt tgtattgctt tttccttatc ccttaatgat atatcatcac
      841 gttttccctt tgggggttta tcagtaggta caagtttcca agagtaaaca aattgtggtt
      901 taccaaatga atatacatac ttatatgcgt atcttccatc ttttctctgg ctctctccag
      961 ttcttaaaat tctatcttta ttatctcgtc ttttttcagt tgacatgata agaagctcct
     1021 ctcaataacc gaattgagct tgatacgtca tatgaatatt ataacatata aggctcaatt
     1081 tcattagata aagtcaagtg tatcaacgat tttctcaaat tgttttctct ttatttgaat
     1141 gcgattgcta ttcataatga cccagccaga atcaaggttt tcatcagcaa gtttacgtaa
     1201 ttttttctct ccaatacgaa agtattttga cgcttcttca atcgtcaagg tatatttttc
     1261 ccaaataggt acatcagtat tgttcataga atgtatcact cctttctatg ttcgtagttc
     1321 agaagtagat agatggcttt ggtaagctcc attggtattt taaccaatcc cattcttatg
     1381 ggcagaaccg tgtcatacag gtgtatcatt atactgtggt acaggttacg gcaaaacaac
     1441 cgttccaaag gttattcaca aatcactata tagtagctct cttgattaag gtcatggcgt
     1501 atagtatttg ttggctatct gtatcacaaa cgtatctatc tactttattc agttgtcaaa
     1561 gaacagtcgg cattgatttg tctataaaaa atcacaatag cttatgggct tttatagaca
     1621 aataattagt gattctccat gtaccaaata gcttgataca tggagagagg gcgagattaa
     1681 gacaaattaa atctcaaaat agcagtgatt agttttgttc ctagcattcg ctttgtttct
     1741 tcttctacat gaatataggg atttccgtat tcatcaaata aagttttctg tgaaagacga
     1801 atgatatagt gttcaaaatg tttaagtatt ccgtttattg catttacatc gccatgtaca
     1861 gcaagtaaaa taattgtaaa aggtaatact tctttagtag gtttcatttc aatgttcctc
     1921 catgagttct ttcaactctt ttagtgcatt tgttttgtga taatgtatgg tattttctgc
     1981 taaatccatc aatgttgcta tgtcagcatt tgtcatgttg agaaagaatg aaagtagaat
     2041 tatatcttgt tttctttttg taagttttcc gattgcttgt gccattaata catcttcaat
     2101 tcgtatgttg tagtcgtaag aaaccataca gatgtagtta gaatcataat catctaaaat
     2161 actcaattta cttaattctg caagtgacaa agattcgaga gataccaaat aatcatttct
     2221 gcgtttattt tcgtcataaa tatctctagc atagttacgc aaaactgttt tacagaaact
     2281 gtcgaattga tgttcaattg tcttttcatc aaccataaga tttcaccctc tttccatcgc
     2341 aaggagttaa ataaccttgc ttactcctat cacggtggga gggcgttaaa tcttcgataa
     2401 atttcaaaaa aaagagaaaa aaatacacac tctgcctata gggcaaaaat gtgtattctt
     2461 taaaacgtat ttaatttata ttggttgtaa gccaccacca tattgatgta tggaaatatg
     2521 cattggctag cttttcataa aaatacaaag atgcataaga aattaataga ggggaaaaac
     2581 ttattctgtt attaaaaagt aggttaattc taataaatgc tattgcggtc gaattaaact
     2641 atatacatgg caatcaatca tgtttctatt ctttattatg aattgtgaca gtattcttca
     2701 atcttaaaac cacatttttc caatacttta cttgaccctc tattgtagga atatacatta
     2761 gcatgaattt tgttaaggtt gtatttttca aaggcaattt tgcatatttc ttttactgca
     2821 tttgttgcta tccctttgcc ccaatagttc ctagcaagcc agtaacctaa ttcagcattt
     2881 ttattaatag aggtatcttc ttcaaatgtt aggctgatac ttccaatagc cctttcttga
     2941 taaaaaatag catagctaag ttgtttaaca tctggagttg ccaaacaaaa actaacaaaa
     3001 tctctagcgt tttgctccct ataagggtgg gggaagttgt cacgaagatt ctttgcaatt
     3061 tctttatcat tcgcaaactc aactaaatcg gtaatataag cataattcca ctctataagt
     3121 tccatttttc ttctcctttt atgaaacagc tacaagaaat ctttctaagc caataccact
     3181 tatcaaacag cgttcttttt tatttccaag catttgataa gtccagtcaa caaatccacc
     3241 gtcaactatt tcaacggttt catttccttg tttgaccgat aatttgaaat tgataccttt
     3301 ataataatta ttatcaacat catcattatg aattgataac tctatattag gaaaaataag
     3361 tttgatagtt tcaaccattc tgtcgaaaaa tccgtcatta tctttgtatc cgtttctttt
     3421 gcgtagaata atagagaaac gaacattttc tatttcactt aatatatctt tataatagtt
     3481 taagtgcttt tctaacaaca ttttttcaca agtgtaagac cctgtatcta taccagatga
     3541 aaccatacaa tataagccaa aatgtgaata taaaccttta cctacaaaat tttgtgctct
     3601 tattacccta gcagtagtag ccatgtggat aggtatggta ttattttctt cttttctttt
     3661 taatttatca gcaataatta ttgccaacat atttgagggg tctgcaagtg tttctgtccc
     3721 tcgtagagca cttactacat tatattgatc tacggagcca aaaacgctac agctacctaa
     3781 tggagcagag ggagaaagca taatcgtctt gatatccata ttgaatgctt ttctcaataa
     3841 ttttgactcc aaagcatgaa tttcttctgg atctataccg ctagggatag taaatctatt
     3901 tagttggtat gactttagaa tatcagttgc agttaaagta tttgcttgtc tatcaaacac
     3961 ttctaataga agtgagttca aatctgattt tgatagagct gataacttat caactatatt
     4021 cttatcccca attttatttg taattctact taaaatatca ctcatagtta tcctccatac
     4081 tgttactttc aaaataatta tagaatggtt acaacaacta atctaggtca tttgaccaaa
     4141 aatgaaaaaa cactgaatat ttactattca atattttttt actttgggtt tatttgatta
     4201 aatcttgaaa atactgtaat gcaacccttt cagcttcaac ctttcggaca ataggacttt
     4261 gtgataattc ctctcttaac tcaagataca ggttgatagt agcctgcaat gcattaacac
     4321 agcttttata ttcatggtta gcaaccgtct tttctaatgc ttcaatatat tggggtgcgt
     4381 ccaattcaat ttttctaact ccacgaggta atttacctaa gagaagctgt attaatgggg
     4441 caagtactga ttgtcttaaa aaagataaaa aatcaattgt ttcaaatagt tctctacgtc
     4501 caatcttagt gcaagcgtaa tgaacccaaa tccaaaatct atcttcaatc cactgtaagt
     4561 ctggagttgg gaagtatgct tcttttttag tataacacct ctcactttct tttattagct
     4621 atcaatccaa cataattatg cataggagta ttatataatg aaaaaataaa aaaaaatagg
     4681 tcacttgacc cgaaataaaa aagcattgaa taattattat tcaatacttt tttgaaatta
     4741 tacttatgtt gtaggaagat tctttaatac ctctcgctga ttaattacac taaatctttt
     4801 gttttcataa gcaattagat gttcttgtac acattcattt atagcacgat taatgcttct
     4861 aattggagcg tttacttcgc tagcaagctg ttttttggta agcagattta attcacttct
     4921 ataatagtgt aaggatatac acctcagaag tcgttcttta acacttaaag atgataattc
     4981 ttcaattaat tcagcattta caactaattt actagatatt tctcgaatca gaaattttgt
     5041 agcttcaaaa tctcccctta accagtttaa aaaatcatct ctatgaagtt tatatacatt
     5101 acaatctgtg aaagcgacaa tttcaacggg ttttttccca tcattaaatt gttccatttc
     5161 tccaaaaaaa ctaccacttc tataaagatg aatagttgag atgtttcctt tcacatttaa
     5221 gatgaatgct tctgcaatac cgtcaatcat aagaattaca tattcatttt cttgctcagc
     5281 aaaaagaata gtctctttct ttttatacgt ttttttaaca agcttctttt taatatcttc
     5341 attcataaaa tcaattaaat gcatattcat ccctccttac caaatctttg attaaattat
     5401 atcatctttc aattagttag gtaagatagt aaaaatatat ttacatagaa actattccat
     5461 tattattttc cagttgtcat ttttctgcaa agtaagctca aactgagaaa gctgttgaca
     5521 atagaactag taggaatata tgagcgaacc atttcagtat tcaactgttg taggttttca
     5581 gtcagataat tcttcaaacg ttcaattcgt ttgtcctgtg aatcttgcga tgctctaacc
     5641 agtttcatag atagcgtttt accttgtgcc acctgcaaaa aagaccatgc ttcgtcaagg
     5701 tcaactatct tgaagctaga gcggtcagta tgaataaagt ctaatgcaaa ggtactaata
     5761 acaatcaaca tagcaacact aagaagttct attgttgtat attcttcaaa gctagtgttg
     5821 gcatctggca atacgaggtc agcaacttga ataatattca gctgtttctc caagctgata
     5881 gactgcttca catttccgtc accaaacagt agatgtgcaa aatcatagtc tacaaaactt
     5941 tcgatatggt cggctatgct gttactgata gaagtatctt cttttcgtaa ttcatcaatg
     6001 acaagtaata accctcgctg ttcactttgg gttacattgc ggattgcttt tctaagcact
     6061 gggaacttat cactgtcacg actggagata ccagcaagga atgttaggat atcaatcgct
     6121 aaactttcag aatcattttt acggctcaaa atgacgtaag ggtcaagcaa tcctttgttt
     6181 tcatcattac tggttaaatt gacaatgttt atctcatggg ctatttctgg tagcgtttct
     6241 ttccatttgc cgcgttctgc tttagggtca actatgaccg cctgtccgcc gaatagtacc
     6301 gcatagtaaa caagcatatt gttactgaat aatttaccac cacccaatga accgataaac
     6361 gcagacgcta acacattggt aatagaaccc tttacccatt gactagcaag ggcaggtttt
     6421 agatagacat tctttccagt gtccagattg tagccaagat agatatcctc atgttcgcca
     6481 agggtttgtg tcgctccaaa accaagtcca gccaaaaaat ccgaagtgac atattgaata
     6541 taatcattga tgtaacgttt gctgacagga ataaattcgc catgcaatcc caacatatcc
     6601 ccaaagggac gcacgagctt gagtgataag tcgtcgtaaa agtctttgac ttcatcacaa
     6661 cgccttttta gctcgtcaag atcctttgta gatacacgga caacatagct aagtttatac
     6721 atagattctt tacagttaaa agtctgtttt taaaaaaatg tataaattat aaatcaaaat
     6781 atagatacta tcaatgaccc actaggtgca aaaagcattg atatggttaa attatcagac
     6841 gctaaaagct gggctatccg aatgagtgaa gatgggtgtg cttataaatc cattgacaat
     6901 tataagcgct cactgaaagc gtcgtttttc atggcaattc aagacgactg tattagaaag
     6961 aatccattta attttcagtt aagtgatgtt ttggaagata caacagaacc aaaaatcgct
     7021 ctaacaccag aacaggaaat gggcttatta tcctttatgg agagcgataa gacttattgt
     7081 aaatattatg atgatgttgt tatcctctta gaaacaggac tacgcatttc tgaattatgc
     7141 ggtttgactt tagaattgga tatgaaaaat aaagccatta tggtagacca tcaattgttg
     7201 agtgatacta agattggcta ttatgtagaa gttccaaaga ccacacaggg taagcgagaa
     7261 attccaatga ctgaaagagc ttatcaatca tttgaacgta tcgtggaacg gcgtaagaac
     7321 gctaaagcag aaccaatcat tgttgatggt taccagaact tcctatttct taaacaagat
     7381 ggattaccaa aacaagcaac tcattatcaa agcatgttaa gagcgttagt caagaagtat
     7441 aataagaccc atgaggacaa gctaccaaag attacgccac atacctttag gcatacactc
     7501 tgtacaaata tggctaacaa aggaatgagt cctaatatat tgcaatatat tatggggcat
     7561 aaaaacatta ctatgacgct tggctattat gcacatggtt catttagttc ttcgagagct
     7621 gaaatggaac ggttataatc ctagtagtat gactagagtt tactacttat ttactacttt
     7681 tgatggcatt cttatacggt taaatgccaa cttatgcaaa gtatcttcca aaaagaaaat
     7741 gccgatactc cttgtagata caggatatat cgacatttac caacttatga aaagataatc
     7801 aaatttaata taagtttttc aaataaaaag ataccaaatt ctttttcgag aatctatata
     7861 acattactta agcttggttg gggtataaac aattgagtag ctacttttgt atggtgttca
     7921 actttagtca aaactcttaa gtaatgcaaa tgatttagat tcattaatat tcaatctctt
     7981 cataagtagt gaaattcgag ttatttctgc ataattatac tatgatttat agattaattc
     8041 tattagcatc cagaataata ttgtttatat gagtaaaatt taaagaatat tgtgaaaatt
     8101 ataggatgtt aaaataaatt taggtaaaaa agaagtgttt gtatattata gagtaccttt
     8161 tctaaaatat gtgggattgt tttaagaatt agaataaaaa ttatttttaa attagtattt
     8221 ttataatgta tagtattttt aatgtataat taaattgtgc agaaaataga atttaaagtc
     8281 ctatagaatt tctgattatg gaggagaata tgaaaagaaa agttcaagta aaaaatatta
     8341 ctattggaga aggtagacct aaaatttgtg taccaattat tgggaaaaat aaaaaagata
     8401 ttataaaaga ggctaaagag ttaaaagatg catgtttgga tattatagag tggcgagttg
     8461 atttttttga gaatgtagaa aatattaaag aagttaagga agttctctat gaattaagaa
     8521 gttatataca tgatatccct ttattattca catttagaag tgtagtagaa gggggagaaa
     8581 aattaatatc aagagattat tatactactt tgaataaaga aatttctaat acaggtttag
     8641 tagatttaat agatgtagag ttatttatgg gagatgaggt catagatgaa gtagttaatt
     8701 ttgctcataa aaaagaagtg aaagtaatta tatctaatca tgattttaat aaaactccaa
     8761 aaaaagaaga gattgtatct cgtttatgta gaatgcagga attgggcgca gatttaccca
     8821 aaatagctgt tatgccgcaa aatgaaaaag atgtgttagt gctacttgaa gctacaaatg
     8881 aaatgtttaa aatttatgca gatagaccaa taataacaat gtcaatgtca ggaatgggtg
     8941 ttataagtag attgtgtggt gaaatatttg gttctgcatt gacttttgga gctgcaaaaa
     9001 gtgtttcagc accagggcaa atatcattta aagagttaaa ttcagtactt aatctattac
     9061 ataagagtat taattaaatt aattatatag aaatattaga cggtattttt gaagatataa
     9121 attaaatata aaaaactttt cagatagtaa aatttaaatt gggcaattat atctgaaaag
     9181 caactattta gtgtgtattt tgaaagtgat atagaaaatc ttataaatca actatggcat
     9241 atttaaaata tgccattaaa acctactaga cattagatta tagatggtat actagcattt
     9301 ctattattta tagatagtaa gttttcataa taactgtttt atctaaagta gaagatatat
     9361 ttgtattatg tatatttgtc attatttttt tgtaattatg tatattaatg gttatatatg
     9421 taatataata ttatcactct attttttgta tattgtacat tacaacattt atatctatca
     9481 tcatcaatta cagtagaatg tatgggatac ttattttcac ttaaccaata tttttgcata
     9541 ttctttgtcc aagactttgg aaacttcaat actttcttgt ttattataac atcctcatct
     9601 tcaaaaatat taacttctct ttctattttt atttttctgt tgtatatctt attgatagat
     9661 tctttgtcga gttt
//
LOCUS       DAJMZY010000129         9584 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.131, whole genome shotgun sequence.
ACCESSION   DAJMZY010000129 DAJMZY010000000
VERSION     DAJMZY010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9584)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9584)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9584
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.131"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            491..1696
                     /locus_tag="OE968_003318"
     CDS             491..1696
                     /locus_tag="OE968_003318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HCP7220559.1"
                     /translation="MSKKVLIMSASTGGGHNRAALAIKEELTSKTLDGEPIECEIIDS
                     LKLVNNTMDKIISRGYEKSAIYTPKAYGSVYRLSETNLLSKNEFKDNLLITFMAKKFK
                     KLIRSEKPDLIIGTHPFPMIALSTLKKNFNLHNNESNAYTEHFYKHYTNTINVPPLIS
                     VLTDYTTHSTWIQNEIDYYIVGHEYVKELLVFDGVEPSKIRTFGIPVEKSFLSHRDKD
                     IVLSELNLSPDKLTVLLMGGSFGAGNIKETLDELLDTDRDFQILVITGKNESLKEKIE
                     KKLMSRYHDKNVCVLGYTDKMNDILASIDVLVSKPGGLTTTEALLKDVPMIVPYYIPG
                     QEEENLDFLSNCGAALRTTKKYNLSILLKVLIDDPSRLEMLKRNIKSIRKSNSAQNIA
                     NLILNIISG"
     gene            complement(1767..1988)
                     /locus_tag="OE968_003319"
     CDS             complement(1767..1988)
                     /locus_tag="OE968_003319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220560.1"
                     /translation="MKPIMNLEEHNAMKEKRVKKMKSKDKPKYDDFEDISFSNKKKTK
                     KNVRNKNAEFRNNYKNYQYDYEEDFYEPI"
     gene            complement(2129..2728)
                     /gene="recR"
                     /locus_tag="OE968_003320"
     CDS             complement(2129..2728)
                     /gene="recR"
                     /locus_tag="OE968_003320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012634696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HCP7220561.1"
                     /translation="MQVYTGPITRLIEEFSKLPGVGRKTAQRLAFHIINMNTNDVEAL
                     SKAIIDAKREIRYCSICCNITDTDPCSMCSNKSRDSSVICVVEDPRDVAAMERTREFK
                     GQYHVLNGVISPMDGIGPDMLKIKELIQRLGNQEVKEIIMATNPTIEGEATAMYIARL
                     VKPMGIKVTRIAHGLPVGGDLEYADEVTISKALEGRREI"
     gene            complement(2741..3091)
                     /locus_tag="OE968_003321"
     CDS             complement(2741..3091)
                     /locus_tag="OE968_003321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HCP7220562.1"
                     /translation="MAKKGFGGGMMPGGGNMNNLLKQAQKMQENMQKAQQELESKEVE
                     ASVGGGAVTVKVNGKKEVIDITIKPEVVDPDDIEMLQDLVLSAVNQALRNIDDIQASQ
                     MSKVTGGMNIPGLF"
     gene            complement(3150..4787)
                     /gene="dnaX"
                     /locus_tag="OE968_003322"
     CDS             complement(3150..4787)
                     /gene="dnaX"
                     /locus_tag="OE968_003322"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HCP7220563.1"
                     /translation="MHKALYRAYRPQKFEDVIGQDHIIKTLKNQIYSDNIGHAYLFCG
                     TRGTGKTSTAKIFSRAVNCLNKINEEPCNECEICESVLKDNTMDVVEIDAASNNSVDD
                     IRELRESVKYSPANAKYKVYIIDEVHMLSQGAFNALLKTLEEPPSYVIFILATTEPHK
                     IPATILSRCQRYDFKRVTVKDMTLRMKKICEDEGIDIDDKALNLIARNSQGALRDALS
                     ILDQCMSFGESKIDYKDVVELMGSVNIEQLFELSQCIVEQDTKKSLEILNEFVLWGKD
                     IRNLINDLIDHFRNLMVCKVSSELDEIISLPEETIEQLKIQSKNIDINDLIRILNILS
                     ITQDDIKSSSNPRVLVEITIMKIAQPMFDESKEALIKRVENLEKMIELGNFKSEKIGN
                     NKEKEYEVDREIDVKQENVVYEDVKNEDVILIESSWKNILKQIKKDKKMPIYALLSEV
                     KSFNVYSNMLYVIFDDKFDFAKTRLSSQDTINYLEKTIRDVLNRSFNVKIVLTSEVKD
                     INLEVKEKKDIGEEILKNIVSEEILEIKDSIDENESK"
     gene            complement(4864..5128)
                     /gene="ffs"
                     /locus_tag="OE968_003323"
     ncRNA           complement(4864..5128)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="OE968_003323"
                     /product="signal recognition particle sRNA large type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01854"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF01854"
     gene            complement(5166..5257)
                     /locus_tag="OE968_003324"
     tRNA            complement(5166..5257)
                     /locus_tag="OE968_003324"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5221..5223),aa:Ser,seq:gga)
     gene            complement(5258..5713)
                     /locus_tag="OE968_003325"
     CDS             complement(5258..5713)
                     /locus_tag="OE968_003325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HCP7220564.1"
                     /translation="MESSFYMKEALKEAYKAYNKKETPIGAIIVKDNQIIARAHNLTE
                     TLKDSTAHAEILAIKQASEKLGGWRLTDCDLYVTMEPCIMCSGAIVNSRIKKLIIGTR
                     HVKNSYIEKQHEFKLDYFNNNNVKVAFDVLQEECSIILQEFFKALRKRD"
     gene            complement(6034..7305)
                     /gene="serS"
                     /locus_tag="OE968_003326"
     CDS             complement(6034..7305)
                     /gene="serS"
                     /locus_tag="OE968_003326"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HCP7220565.1"
                     /translation="MLDIKRIRENLDDIKKAMERRGEREFDLDAVVELDNKRREILQE
                     VEVMKNELNVNSKKIPQLIKEGKDVTEEKARLKELSDKIKGIDEKVKEVEAKMEYTLM
                     RIPNVPHPEVPQGETDEDNVQIRTWGEPTKFDFEHKAHWDIGTGLGILDFERAGKITG
                     SRFTLYRGLGARLERSLMNFFLNTHTAKHGYTEVLPPFMANRNSFIGTGQLPKFEEDM
                     FKIEGLEYFLIPTAEVPVTNIHANEILDVAELPIKYCAYTPCFRSEAGSAGRDTRGLV
                     RQHQFNKVELVKFVKPEDSYNELESLTHDAETMLQMLGLPYRVVKICTGDLGFTAAFK
                     YDLEVWMPSYNRYVEISSCSNFEDFQARRAGIRFKRDKKSKAEYVHTLNGSGLAIGRC
                     LAAILENYQQADGSVVVPEELRPYMGVDVIK"
     misc_binding    complement(7431..7636)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(7764..8645)
                     /locus_tag="OE968_003327"
     CDS             complement(7764..8645)
                     /locus_tag="OE968_003327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HCP7220566.1"
                     /translation="MNFLSLAKTASTNSNITKRTLENMLDNFSDNIPNIIYAIIVFVI
                     GIYISKIVRRMVSKFLIKYGMSKGVNNFIVYGIYISMLSIISLISLGIIGIQTTSVVA
                     VLGAAGFSIGLAFKEILSNLGSGMIILFFKPFNIGDYIQGSGVEGTVSDIQIFSTVLK
                     TPDNKTIIIPNFQLTSNNIINYTHQNKRRIDFSYNISYDSDIDVVKSILNEIFTNEKR
                     ILNDPKPIIGLNSIGNNTMQIVARPWVKTDDYWDVYFDVMEKVKNKFDENDIKVPFVP
                     SSLLFNNTGNLNTMDKR"
     gene            complement(8657..9166)
                     /locus_tag="OE968_003328"
     CDS             complement(8657..9166)
                     /locus_tag="OE968_003328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HCP7220567.1"
                     /translation="MNSNERRSKLIDILKESKHPVKGGTLAELLNVSRQVIVQDIALI
                     RARGFEIIATPQGYIIYNQPYFTKQIKCKNHKDSKEIYDELKIIVDLGGIIKDVIVNH
                     PTYGQITAELNIYSKMDIDNFMKKVETNEFKQLSVLTECSHIHTIEAIKEETIEAIVK
                     ELKDNGILS"
     gene            complement(9292..9408)
                     /gene="rrf"
                     /locus_tag="OE968_003329"
     rRNA            complement(9292..9408)
                     /gene="rrf"
                     /locus_tag="OE968_003329"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         3057 a         1678 c         1030 g         3819 t
ORIGIN      
        1 ctcagatact attgttatca aaatatctgg ctttatggtt tgtttcttaa tataaattaa
       61 cctactgttt aattttcaat gttcgtgttt atttcttttt ccttttttca aggacaagta
      121 atactatatc atctttatct attctagtca atataatttt ttactttttt taattttttt
      181 atttatcatg tattctttat ctttaatttt taaaacttaa tgctaagtaa acctgtttat
      241 ttcataaaac taatatatat tctatgctct attttccttt ttattctata tttaaatttt
      301 ttatttacaa gaatattttt aatataacat atttgataaa attaatttac atttctttca
      361 cttgtaattt ttgcaatctt gtattagatt aatattaaaa ataatttatc aataacctta
      421 ttcacaaaga cagtttttat atatcaaaat ataatataaa tactatgcta cattttagga
      481 ggattttatt atgagcaaaa aagtattaat aatgtctgct tccactggtg gtgggcataa
      541 tagggctgct ctagctatta aagaagaact tacttccaaa acacttgatg gagagccaat
      601 tgaatgtgaa ataatagata gtttgaaatt agttaataat acaatggata aaataatttc
      661 aagaggatac gaaaaatctg ctatatatac tcccaaagcc tatggaagtg tatatagatt
      721 atctgaaaca aatcttttgt caaaaaatga atttaaagat aatctactaa taacattcat
      781 ggctaaaaaa tttaaaaagc ttattagaag cgaaaaacca gacttgatta taggaacgca
      841 tccttttcca atgattgctc taagtacatt gaaaaaaaac tttaatttac ataataatga
      901 atcaaatgct tacacagagc atttttataa acattataca aataccatta atgttcctcc
      961 gcttatttct gtattaaccg attatactac tcattctaca tggatacaaa atgaaattga
     1021 ttactatatt gttggtcatg aatatgtaaa agaattattg gtgtttgatg gagttgaacc
     1081 gagtaaaatt agaacatttg gaatccctgt tgaaaaatct tttctctctc acagagataa
     1141 agatattgtt ctttctgagt tgaatttatc tcctgataaa ttaactgttt tacttatggg
     1201 gggtagcttt ggggctggaa atataaaaga gacacttgat gaattactgg atactgatag
     1261 agactttcaa atacttgtaa ttactggtaa gaatgaaagc ctaaaagaaa aaatcgaaaa
     1321 aaaacttatg tctcgttatc atgataaaaa tgtatgtgtc cttggataca ctgataagat
     1381 gaatgatatt ttagcttcta tagatgtatt agtaagcaaa cctggtggac ttactacaac
     1441 tgaggctctt ttaaaagatg tacctatgat agttccttat tatataccag gtcaggaaga
     1501 agagaatctt gatttcttat ctaattgtgg tgcagcactt agaactacaa aaaaatataa
     1561 cttgtcaata ttactaaaag ttttaataga tgaccctagc agattagaaa tgctaaaaag
     1621 aaatattaaa tcaataagaa agtcaaattc agcccaaaat atagctaatt taattttaaa
     1681 tataatttct ggttgataaa ataaataaaa tccctatagt atatatatta tctattaggg
     1741 attttttatt ttctaattat ttaatattaa attggctcat aaaagtcttc ttcataatca
     1801 tactgataat ttttataatt atttctaaat tcagcatttt tatttcgtac atttttttta
     1861 gtttttttct tattagaaaa acttatatcc tcaaaatcat catatttagg tttatctttt
     1921 gatttcattt ttttaactct tttttctttc attgcattat gttcttctaa gttcataatt
     1981 ggtttcatgt tgcaccccta tcaaaatttt taaatgattt atacaacaaa ttatacaata
     2041 cagaagaaat ttattcaata aatctaaatc aaaattaatt tgaatttaac tcaaaaaact
     2101 acaaaaatcg aggtattaac ctcgattttt atatttctct tctgccttct agtgcttttg
     2161 atattgtgac ctcatctgca tactctaaat cgcctccaac aggaagacca tgagctatcc
     2221 gagtgacttt gattcccatt ggttttacta acctagcaat atacatggct gtagcttcac
     2281 cttcaatagt aggatttgtt gccattatta tttctttgac ttcctgattg ccaagtcttt
     2341 ggataagttc ctttattttt aacatatctg gtccaattcc atccattgga gaaattactc
     2401 catttaatac atgatactgt cctttaaact ctctcgttct ctccatagct gctacatctc
     2461 ttggatcttc cacaacacat ataacacttg aatctctact tttatttgaa cacatgctac
     2521 atgggtctgt atctgttata ttacaacaaa ttgagcaata tcttatttct ctttttgcat
     2581 ctataatcgc tttagataaa gcttccacat cattagtatt catattaata atatgaaaag
     2641 ccaatctttg agcagtcttt cttcctactc caggaagctt tgaaaattcc tctataagtc
     2701 tcgttatggg acctgtataa acttgcataa ataccaccta ctagaataac ccaggtatat
     2761 tcatacctcc agttacctta ctcatttgac ttgcttgtat atcatcaata tttctcaatg
     2821 cttgatttac tgcacttaaa actaaatctt gtagcatttc tatatcatct ggatcaacta
     2881 cttctggctt gatagttata tctataactt cttttttacc attaactttt acagtaactg
     2941 ctcctccacc aactgaagct tctacttctt tactttctaa ctcttgttga gctttttgca
     3001 tattttcttg cattttttga gcctgcttta acaagttgtt catatttcca ccaccaggca
     3061 tcattccgcc tccaaaacct tttttagcca taaacactat tcctcctaaa cttattttca
     3121 ttttattatt atatcataat agtattttat tatttactct cattttcatc aatactatct
     3181 tttatttcta atatctcttc actcactatg ttctttaata tttcctcacc aatgtccttt
     3241 ttctctttaa cttcaagatt tatatcttta acttctgatg tcagtactat ttttacatta
     3301 aaacttctat ttaaaacatc tcttattgtt ttttctaaat aatttattgt atcttgagag
     3361 ctcagtctag tttttgcaaa atcaaattta tcatcaaata taacatacaa catattagaa
     3421 tatacattaa aactttttac ttcacttaag agtgcgtata ttggcatttt tttatctttt
     3481 ttaatttgtt taagtatatt cttccaagat gactctataa gtataacatc ctcatttttt
     3541 acatcttcat aaactacatt ttcttgtttt acatctattt ctctatcgac ctcatactct
     3601 ttttctttat tattcccaat tttttcagac ttaaagttcc ccagttcaat cattttttct
     3661 aagttctcaa ctctttttat aagagcttct ttactttcat caaacattgg ttgagcaatt
     3721 ttcattatgg ttatttccac taaaaccctt ggatttgaag atgactttat atcatcctga
     3781 gttattgata atatatttaa aatccttatt aaatcattta tatctatatt tttagactga
     3841 attttaagtt gttctatagt ttcttctggt aatgaaatta tttcatccaa ttctgatgaa
     3901 accttacata ccattaaatt tctaaaatga tcaattaagt catttataag atttcttata
     3961 tctttgcccc ataagacaaa ttcatttaat atctcaagag actttttagt gtcctgctct
     4021 acaatacatt gagacaattc aaataattgt tctatattta cgcttcccat taattcaaca
     4081 acatctttat aatctatctt actttctcca aaagacatac attggtctaa tatactaagt
     4141 gcatctctaa gagctccttg agaatttcta gctattaaat taagagcttt atcatctata
     4201 tcaattcctt catcttcaca aatctttttc attctaaggg tcatatcttt aactgtaact
     4261 cttttaaaat cgtatctttg gcatcttgat aaaatggttg caggtatttt gtgaggctct
     4321 gtagttgcta atataaaaat tacatatgat ggaggttcct ctaaggtctt taataatgca
     4381 ttaaaagctc cttgagacaa catatgaact tcatctatta tatatacttt atatttagca
     4441 ttggctggag aatatttcac actttctcta agctctctta tatcatctac actattattt
     4501 gaagctgcat ctatttctac aacatccatt gtattatctt ttaatacaga ttcgcatatc
     4561 tcacactcat tacacggttc ttcatttatt ttattcaaac agtttactgc tcttgaaaaa
     4621 atctttgcag tagatgtttt accagtacct cttgttccac aaaacaaata agcatgtcct
     4681 atattatcac tatatatttg attctttaaa gtcttaataa tatgatcttg accaataaca
     4741 tcttcaaatt tttgtggtct atatgctcta tataatgctt tatgcatctt tttacctctc
     4801 tttagcaaaa ttaataaaaa aatccctcat tatctaaggg attagtcttt tatatattaa
     4861 atgctgtaca ccatctatcg acttaattcc ataggcgtta ccaaaacagt tagctcaact
     4921 taggcacccc cacggcacac aaaagtgatc acttaccgct gcttccttcc ggatctgacg
     4981 gggttcatga gctttcattg cgcaggacct aagcatcaac accacttatt tagggcggcc
     5041 ctacagaaaa taagccttta gatggaattc aatcctgcta tagcggattg caggttacag
     5101 ggcaccgcta cctccccatc tagtacagca aaattacaac catatttaat tactttcatt
     5161 gtttctggcg gagagagtgg gatttgaacc cacgatacag ttttacccat atactcgctt
     5221 tccaggcgag cgccttcgac cactcgacca tctctcctta atctcttttt ctcaatgcct
     5281 taaaaaattc ttgcaatatg atcgagcatt cttcttgcaa aacatcaaaa gctactttta
     5341 cattattatt attaaaataa tctaatttaa actcatgctg tttttctata tatgaatttt
     5401 ttacatgtct tgtccctatt ataagctttt ttattctaga attaactatt gcgccactac
     5461 acattatgca aggttccatt gtaacatata aatcacaatc agtcaacctc caaccaccta
     5521 atttttctga tgcttgtttt atcgctaaaa tttctgcatg tgccgtagag tcttttaacg
     5581 tttctgtaag gttatgagct ctagctatta tttgattatc tttaactata atagcaccta
     5641 ttggtgtttc ttttttatta tatgctttat atgcttcttt taatgcttct ttcatataaa
     5701 atgaactttc cataattcct cccaaaactt ataacaaact tatcttatca taattcattt
     5761 tataattcaa cttaatttta ttttgtttat ttaattatta ctatatatag ctatattttt
     5821 tttaaattag ttctaaaata atttttagat attcatacaa gagtgtttta taaaaatatt
     5881 tagtgtttta tgatgaaaat tctgctgtgt aaattaacat aaaaaaacta tgaaattaat
     5941 atttataata atttcatagt ttttttattt attgtttact cataatatat tctcttcatc
     6001 aaagcatact ctacatatac aattaatata aatttatttt ataacatcaa cacccatata
     6061 aggtcttaat tcttctggaa ctactacaga accatctgcc tgctgataat tttctaatat
     6121 agcagccaaa catcttccta tcgctaatcc agaaccattt aatgtatgaa catattctgc
     6181 ttttgatttt ttatcccttt taaatcttat tcctgctctt cttgcttgga aatcttcaaa
     6241 atttgaacaa gaagatattt ctacatatct attgtagctt ggcatccaaa cttctaaatc
     6301 atatttaaat gcagctgtaa atcccaaatc tcctgtacat atttttacaa ctctatatgg
     6361 aagacctaac atttgtaaca tagtttcagc atcatgagtt aatgattcta attcattata
     6421 agaatcttct ggtttaacaa atttaactaa ttcaacttta ttaaattgat gttgtctaac
     6481 taaacctctt gtatctcttc ctgctgaacc tgcttcagat ctaaaacaag gagtatatgc
     6541 acagtattta attggaagct ctgcaacatc taatatttca ttagcatgta tattagtaac
     6601 aggaacttca gctgttggta ttaagaaata ctctaatcct tctattttaa acatatcttc
     6661 ttcaaattta ggaagttgac cagtccctat aaaactattt ctattggcca taaatggagg
     6721 taagacttcc gtatagccat gcttagctgt atgagtattt aaaaagaaat tcattaaaga
     6781 tctttctaat ctagctccta atcccctata taaagtaaac cttgacccag ttattttccc
     6841 tgctctttca aaatctaaaa tacctagacc tgtacctata tcccaatgcg ctttatgctc
     6901 aaaatcaaat ttagtaggtt ctccccaagt tcttatttga acattgtctt catctgtttc
     6961 accttgtggt acctctggat gaggaacatt tggtattctc attaatgtat attccatttt
     7021 tgcttctact tcttttactt tctcatcaat accttttatc ttatctgata actctttcaa
     7081 tcttgccttt tcttctgtta catcttttcc ttcttttatt aattgaggta tttttttaga
     7141 atttacattt aactcatttt tcataacttc aacttcttga agtatttctc ttcttttatt
     7201 atctaattcc actacagcat caaggtcaaa ttctctttca cctcttcttt ccatagcttt
     7261 tttgatatca tctagatttt ctcttattct tttaatatct aacatattaa ttcctcctaa
     7321 taattttgat aatataagtt ataattccaa cttaatttac aaacattata cttgtaaact
     7381 cttagtttaa acaaatttta aaaataaaaa aagacctccg tttaccctat aaaagggacg
     7441 aaaatctttt atccgcgttg ccaccctaat tgactatact aaaatgtata atcctctcag
     7501 acctataacg taggtaaacg tctagcttta actagaagct ctagagtaga ttcaaaaacc
     7561 attgtaatga gttttcacca tccactcatt ctctgaatac aatctgtttt ttactatttt
     7621 ccttcacagc tttttaacta attgttttat ttgataatca ttatattata tatattaaca
     7681 tctttcaata ctattattca aattttttta gaattttctt taatttttta tattaaattc
     7741 attttttcta tttaattaag accttatctt ttatccattg tatttagatt acctgtatta
     7801 ttaaataata atgaagaagg aacaaatgga acttttatat cattctcatc aaatttattt
     7861 tttacctttt ccattacatc aaagtataca tcccagtaat catcagtttt tacccaaggt
     7921 ctagcaacta tttgcatggt gttatttcct atagagttta gacctattat aggctttgga
     7981 tcatttaata ttcttttttc gtttgtaaaa atttcattta atatagactt aactacatct
     8041 atatcactat catatgaaat attatatgaa aaatctattc ttcttttgtt ttgatgtgtg
     8101 taattaatta tattattact tgtcagttga aaattaggta taattatagt tttattatct
     8161 ggcgtcttaa gaacagtgct aaatatttgt atgtcagaaa ctgtaccttc tacacctgaa
     8221 ccttgaatat aatcacctat attaaatggc ttaaaaaata aaataatcat accagagcct
     8281 aaatttgata atatttcttt aaaagctaaa cctatactaa atccagcagc tcctaacaca
     8341 gctacaactg atgtagtttg tatccctata atacctaagc ttatcaatga tataatagat
     8401 aacatagata tatatattcc atatacaata aaattattta cacctttact cattccatat
     8461 ttgattagaa actttgaaac catccttctt actattttag atatataaat acctatcaca
     8521 aatacaatta ttgcatatat aatatttggt atattatcac taaaattatc gagcatattt
     8581 tctaaagttc tcttagttat attgctattt gttgaggcag tcttagccaa tgataaaaaa
     8641 ttcattcaac tcctccttat gataatattc cgttgtcctt taactctttt actatagctt
     8701 ctatagtttc ttcttttatt gcctcaattg tatgaatatg gctacattct gtcagaaccg
     8761 ataattgttt aaattcattt gtctcaactt tcttcataaa gttgtctata tccattttag
     8821 aataaatatt aagttctgca gttatctgac catatgttgg atgatttaca ataacatctt
     8881 ttataatacc acctaaatct acaattatct ttaattcatc ataaatttct ttagaatcct
     8941 tatgattttt acactttatt tgttttgtaa aatacggttg attatatatt atatatcctt
     9001 gaggtgtagc tattatttca aatcctctag ctcttataag ggctatatct tgaactatta
     9061 cttgcctact tacatttaat agttcagcta gtgttccacc ttttacagga tgcttagatt
     9121 cttttaaaat atctattaat ttacttcttc tttcattaga attcatatta caccttcttt
     9181 ccaaataaaa actttaccta tactatataa ttttatattt tatcttatta taaatcaata
     9241 ttgactttat attctattta atcttaactt ttataataaa taaaaaagac tacgtggcta
     9301 cgtcctactc tcccaggcag tttcccacca agtaccatca gcgctagaga gcttaacttc
     9361 tgtgttcgga atgggaacag gtgtatcctc tctgctattg taaccacata atctttatgc
     9421 ttaatatttc tattaagttt ttaataagtt tctagaatct agtaatacta gtttctttag
     9481 agttagcact ctaaaaacta cacatatatc ttaatgaatg aacatcaaat aaatattggt
     9541 caagtcctcg acctattagt atcgataagc taaatacatt gctg
//
LOCUS       DAJMZY010000130         9434 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.132, whole genome shotgun sequence.
ACCESSION   DAJMZY010000130 DAJMZY010000000
VERSION     DAJMZY010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9434)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9434)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9434
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.132"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            <1..445
                     /locus_tag="OE968_003330"
     CDS             <1..445
                     /locus_tag="OE968_003330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HCP7220568.1"
                     /translation="DIIKIPEELKFCAMIPNFKLSTEKARGVLPKEIPYSDGVFNVSR
                     VALLISALLNKNFDLLKVACQDKLHQDYRGTLIENYNDIVEKSEQLNSIGVFLSGAGP
                     TIMSLIKENDDSFVDNMKNYLQKLKSDWEIKELCCDSNGAVLNII"
     gene            569..1630
                     /locus_tag="OE968_003331"
     CDS             569..1630
                     /locus_tag="OE968_003331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015617764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitronate monooxygenase"
                     /protein_id="HCP7220569.1"
                     /translation="MIIKELIIRDLVAKVPIIQGGMGVGISRSSLAGAVAKLGGVGVI
                     SGVQIGYDEEDFETNTINANLRAIKKHISKAKEISNGGIIGINFMVAMKEYETYVKEA
                     VKAGVDLIISGAGLPNKLPSLVKGSNVKIAPIVSTAKAANVILKMWDRKEKTTADLIV
                     VEGPKAGGHLGYSNEELDNIDSIDYDKEFVEILKVANTYGEKFGRNIPVVAAGGITSS
                     SDVKKYIDMGASGVQVGTRFVATYECDAHENFKMAYINASEEDVHIVKSPVGLPGRAI
                     RNKFIEEVKINRPEIKKCYNCLIPCNPKETPYCISQALINAVKGDVENSLLFCGNDAY
                     KIDKLSTVEDVINELISEL"
     gene            complement(1785..2297)
                     /locus_tag="OE968_003332"
     CDS             complement(1785..2297)
                     /locus_tag="OE968_003332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HCP7220570.1"
                     /translation="MSDFKEILAEEIKNNPFGLIGKDWTLITAENEGKVNTMTASWGG
                     LGVMWGKDVAFVVIRPQRYTKEFIDNTDKFSLTFFDEDFRKELSYCGKVSGREEDKIS
                     QIGFNIEHLNDTPYFKEAKMAIICKKMYSQKLEPQCFIAEGIDGRWYPQKDYHTLYIA
                     EITNVLVKED"
     gene            2817..3752
                     /locus_tag="OE968_003333"
     CDS             2817..3752
                     /locus_tag="OE968_003333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HCP7220571.1"
                     /translation="MIRYYKTIDSKLEKLSFFEDGCWINLVEPNHSEINEISNLLNID
                     VESIESALDEEERSRIDVEDNHTLILIDIPVDESDSNSSHYTTIPLGIILTEEAIVTV
                     CDAQTKILNDFIVGHIKDFFTFKKTRFLLQILHKNAAYYLHYLRKINKMTIIIEREIY
                     KSMKNKELVQLLELEKSLVYFSTSLKSNELVLNKMVRTAGIKKYPDDEDLLEDVIVEN
                     RQALDMAKIYGDILSRIMDAFSAIISNNQNNVMQILTVVTLIFSIPTIISGFFGMNVI
                     NMPFSNNPNGFWIILLITSIICIVITFFMSRNKLL"
     gene            complement(3844..5715)
                     /locus_tag="OE968_003334"
     CDS             complement(3844..5715)
                     /locus_tag="OE968_003334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sel1 repeat family protein"
                     /protein_id="HCP7220572.1"
                     /translation="MKNTKFSIKKIKNISNDPKVVHTKGALLEKMGKMESAIELYKSA
                     ALDNYVKSQYTLGNIYESKKQFKEAEKWYSMAYKSGSEDAAFDLGNMYYKLDGYEYAI
                     YWYEKIANLGYLQAQNNLGVCHFKMKDFVRCEKWLKTAADKNLGKACFNLGVLYTFLE
                     KDDEAYEYYKKGSVLLDDDAKYNLAILNGKKKDNKSTVSLYKQLYKSGHMKGCFNLGM
                     IMEINDNLEDAEKYYKKSADRDDVKSEYRLAYVYDRKEELGDAIYYYEKAIEKNHTLS
                     KYRLANLYNRENEIEKAKTYYKMAAEDDITEAKNNLAGIYFEEKDYENAIKYYEDAIA
                     VGCKSSLENLGDLYYQNQDIEKAISYYSRIPNNVSCQIKLGNIYEDLNNIEEAISWYK
                     KASENGDTRSSYRLGCIYESLGNTKNARKYFEMASSKNHMNARIHLGRIYFREGKLEE
                     SKMMFDTPANENNVYAQHMVGLIYDMFYKDYVNSKFWYEKARAQGCVESIYNLGQIYL
                     KLNDDAEAEKYYKEGIKYGSKKCEYMLAGLYYKKSLDMYISLANEEYDNCEEIVEGFP
                     NLNIDFDEVLIPPFKLQEEVIDEEEYVPIYILNIKESLDSMLEGLETEMIIDEEHDS"
     gene            5905..6831
                     /locus_tag="OE968_003335"
     CDS             5905..6831
                     /locus_tag="OE968_003335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HCP7220573.1"
                     /translation="MNFSNIFIQVAVLFIIILVGYFVRKFNLLDDHCTSKLSTLTMTV
                     FLPSMIISSMQINFDSKMIQKILLLLFTSLIMYIVSIIIAFLLKYILKCNDKKDLGIY
                     QYIVVFSNVAFMGYPVIEAVLGHEAIFYTAIFNLPFNLFSFTLGIYLLSKGSTSRGFS
                     IKSLISPATIAIVIGLFLFVTGLRLPQFINEPLEMLGSITTPISMIIIGSLLANSSAL
                     DCFVNKKLYIVTFIRLLVLPVIVYFILKGWINDKMILAIPVVISSMPAAANTAIMANQ
                     YDSNITLASQCVFFTTLFSVISIPFISILLLS"
     gene            6970..7116
                     /locus_tag="OE968_003336"
     CDS             6970..7116
                     /locus_tag="OE968_003336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220574.1"
                     /translation="MDMDLLFKIVFAIVAIGVSVKIIKTVASLAFKIALILLIILFVY
                     RMFL"
     gene            complement(7221..7745)
                     /locus_tag="OE968_003337"
     CDS             complement(7221..7745)
                     /locus_tag="OE968_003337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCP7220575.1"
                     /translation="MSKPIDITIRPIRREDAQAFNEIRRTYSVMRNTLALMSDRVDKT
                     EAMLASLGENDYMFVAETNNNGEKDVIGFAGLHVNSSPRLRHSAEIGISVAENYQGRG
                     VGKKLMEQLLDIADNWIMLTRVGLEVIVDNEKGLNLYKKLGFEIEGTKKYAVIRDGKF
                     EDVYIMGRYNKNLI"
     gene            complement(7798..8022)
                     /locus_tag="OE968_003338"
     CDS             complement(7798..8022)
                     /locus_tag="OE968_003338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220576.1"
                     /translation="MIIKLTKDNFNFRFKQYEGMFFHAEVVEGMESIRYKITKDKEGT
                     ELKEFGSTHIKDNMIYVPQVEAYIDLNSIK"
     gene            8219..9343
                     /locus_tag="OE968_003339"
     CDS             8219..9343
                     /locus_tag="OE968_003339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3810 domain-containing protein"
                     /protein_id="HCP7220577.1"
                     /translation="MSKKTKYFSLILFPIALLLNFIASKVPNIVEKYYSQFIDKIIVQ
                     ILSKVSGIFPFSLYEITMYIIVISIFLFLCCTLSTIFNKKKKLNIYLKNSILNILSIV
                     SIVYFLFVVLWGINYNRIPLETTLINNYNLKNNTSIQSKQYSVKELTKLYKFLVIKAN
                     ETRKLTLQDKNGIVKSNTDYNGVINRAQLGYDNILDILPGVSGSYSKPKYIISSNLMC
                     YTGITGIYFPFTGEANVNIAIPDLYIPCTVEHEMAHQRGFASEDEANFIAYLTSIKHP
                     NIDFNYSGYILALNYTASALSKVDYNAYVDISAGISDSVRRDLKNESEFWQKYEGKIN
                     EISNEFNNSYLKANSVTEGTQSYGKMVDLLLTYYELYPYN"
BASE COUNT         3253 a         1393 c         1140 g         3648 t
ORIGIN      
        1 tgatattata aaaattcctg aagaacttaa attttgtgca atgataccta attttaagtt
       61 atcaacagaa aaagctagag gtgttttacc aaaggaaata ccatattctg atggggtatt
      121 caatgttagt agagttgctt tactaatatc tgccttacta aacaaaaact ttgacctact
      181 taaagtagct tgtcaagaca aattgcatca agattataga ggaactctaa ttgagaacta
      241 caatgatatt gttgaaaaat ctgaacaatt aaatagtatt ggagtatttt taagtggagc
      301 tggacctact ataatgtctt taataaaaga aaatgatgat agttttgtgg ataatatgaa
      361 aaattaccta caaaaactaa aatctgattg ggaaataaaa gagttatgtt gcgattctaa
      421 tggagctgtt ttaaatataa tataattatc gtcttctata caaaatataa ctactctttt
      481 attataattt gtagtataat aattaggact aggtaataat attaagtatt ataatctagt
      541 tctttaaaca tgtttacatt gaggagggat tatcataaaa gagttaataa ttagagattt
      601 agttgcaaaa gttcctataa ttcaaggtgg aatgggcgtt ggtatatcta ggtcatcact
      661 agctggtgca gttgctaagc ttggtggtgt tggtgtaatt tctggagttc aaattggata
      721 tgatgaggaa gattttgaaa ctaatactat aaatgcaaat ttaagagcta taaaaaaaca
      781 tatttctaag gccaaagaaa tctcaaatgg tggtattatt ggtattaatt ttatggtagc
      841 tatgaaagaa tatgaaacat acgtaaagga agctgttaaa gctggtgtag accttataat
      901 atctggagct ggattaccta ataagctacc atcattagta aagggaagta atgtaaaaat
      961 agcacccata gtttcaactg caaaagctgc taatgtaatt ttaaaaatgt gggatagaaa
     1021 agagaaaact actgctgact taatagttgt tgaaggtcca aaagctggtg gtcaccttgg
     1081 atactctaac gaggaacttg ataacataga ttctatagac tatgataagg aatttgttga
     1141 aattttaaag gttgcaaata cttatggaga aaaatttggt agaaacatac cagtagttgc
     1201 tgctggtggt ataacttcta gtagtgatgt taaaaaatat atagatatgg gtgcaagtgg
     1261 tgtacaagtt ggtacaagat ttgttgctac ttacgaatgt gatgcccatg agaactttaa
     1321 aatggcatac ataaatgcta gtgaagaaga tgttcatata gttaaaagtc ctgtaggtct
     1381 tcctggacgt gccataagaa acaaatttat agaagaagtt aaaataaatc gtccagaaat
     1441 aaagaagtgc tataattgtt tgattccttg taatccaaaa gaaactcctt actgtatttc
     1501 tcaagctcta atcaatgcag ttaaaggaga tgttgaaaat tcacttttat tttgtggaaa
     1561 tgatgcctat aaaattgata aattaagtac tgttgaagat gttatcaatg aattgatttc
     1621 tgaattataa tttaaagaaa actaaattaa aattttatca agctaaggag tttaaatacg
     1681 ttatttatta atctttataa acatatttat gtccttagct tttttgtgtc aatttccttt
     1741 tattgaaatt ttaatttaat tagagatagt attaaccctt ataactaatc ttcttttaca
     1801 agtacattgg ttatttcagc tatatataaa gtatgataat ctttttgtgg ataccatctt
     1861 ccatctatac cttcagcaat aaaacattgg ggttcaagtt tctgactata catttttttg
     1921 catataatag ccattttagc ttccttaaaa taaggtgtat catttaagtg ttctatatta
     1981 aatccaatct gtgatatctt atcctcttct ctaccagata cttttccaca atatgaaagc
     2041 tctttacgaa aatcttcatc aaaaaatgta agagaaaatt tatctgtatt atctataaat
     2101 tccttagtat aacgctgtgg tcttattact acaaaagcaa catcttttcc ccacataact
     2161 ccaagccctc cccagctagc agtcattgta ttcactttac cttcattttc tgctgttata
     2221 agtgtccaat ctttacctat caatccaaat ggattatttt taatctcttc tgccaaaatt
     2281 tctttaaaat cactcatatc tctaataacc tctcattctc ttatatttat attcctttta
     2341 ttttcatgat aaattataaa tgaagtctag ttttgaaaat aaaatacttt tttaaatata
     2401 ttattgcaaa taagtaaata tatatataca ctcttatttt ttaatatatt taataatttc
     2461 actcagaata tatatattct ttactcaaat taaatataac ttatatactt tatgtgtaaa
     2521 ttatggtaaa aatattattt aatcaaatca aaacttgatt tatatacctg gaaaaggtat
     2581 tatattaaag agtgcttaaa atacgcattt cataaatagc tatatataaa ataataaata
     2641 aggagagtga tgggcaatgg atactagtcc gttgcggaga gaatttttta cattttcatc
     2701 acttaataat atctaaaatc aaaactaata catatattca gttatataaa ttagttaatt
     2761 aatagatact attaaatgat gagatttata taaaactgaa taaaggatgt gttgccatga
     2821 taagatatta caaaactata gattcaaaat tagagaaact tagttttttt gaagatggct
     2881 gttggataaa tcttgttgaa cctaatcata gtgaaatcaa cgaaatttct aatttattaa
     2941 atatagatgt agaaagcata gaatctgcac tagatgaaga agaacgctca agaatagatg
     3001 ttgaagacaa tcatactctt atacttatag atataccagt agacgaaagt gactctaatt
     3061 cttctcatta tactacaata cccttaggta ttatactaac tgaagaagct attgtaacag
     3121 tttgtgatgc acaaactaag attttaaatg actttatagt tggtcatatt aaagattttt
     3181 ttacgtttaa aaagactcgc tttttgcttc aaattcttca caaaaatgca gcttattact
     3241 tgcattactt aagaaaaata aataaaatga caatcataat agagcgagaa atttacaaat
     3301 caatgaaaaa caaagaattg gttcaattat tggaattaga aaaatctttg gtatacttct
     3361 ctacctcact aaaatctaat gaacttgttt taaacaaaat ggttagaact gctggtataa
     3421 agaagtatcc agatgatgaa gacctattag aagatgttat agttgaaaat agacaggctc
     3481 ttgatatggc taaaatatat ggagatatat tgagtagaat tatggatgct ttcagtgcaa
     3541 ttataagtaa taatcagaat aatgttatgc aaattttaac agtagttaca ctaattttct
     3601 caatacctac aataatatca ggattctttg gtatgaatgt catcaacatg ccattttcta
     3661 ataacccaaa cggattttgg ataatacttc ttattacctc tataatatgt atagtgatta
     3721 catttttcat gtcaagaaat aagctattat aaaatattaa taaaaaagcc attagaatta
     3781 attgatttac atttatccta atggctttta tatatttaaa tctatataat cttataatac
     3841 tttttaacta tcatgttctt catctataat catttcagtt tcaagccctt ctagcattga
     3901 atctaaactt tcttttatat ttagtatata aattggtaca tactcttctt catctattac
     3961 ctcttcttgc aacttaaatg gaggaattaa tacttcatca aagtctatat ttaaatttgg
     4021 aaagccttct actatctctt cacaattatc gtactcttca tttgctaaag aaatgtacat
     4081 atctaggctc tttttataat aaagacctgc aagcatatac tcacacttct tacttccata
     4141 tttaatacct tctttataat atttctcagc ttctgcgtca tcatttaatt ttaaataaat
     4201 ttgacctaaa ttatatattg attcaacaca accttgtgct ctagcctttt cataccaaaa
     4261 tttagaattt acataatctt tatagaacat atcataaatt aatcctacca tatgttgagc
     4321 atacacatta ttttcattgg caggtgtatc aaacatcatt ttagactctt ccaatttacc
     4381 ttctctaaaa taaattctac ctagatgtat acgagcattc atatggtttt tgctacttgc
     4441 catttcaaaa tactttctag cattttttgt atttcctaag ctctcatata tacaccccaa
     4501 tctataacta gacctcgtat ctccattttc agatgctttc ttataccaac ttattgcttc
     4561 ttcaatatta tttaaatctt catagatatt tcctaatttg atttgacaag atacattatt
     4621 tggaatcctc gaataatacg aaatcgcttt ttctatatct tgattctgat aatataaatc
     4681 ccctagattt tcaagggaac ttttgcatcc aacagctata gcatcctcat aatatttaat
     4741 agcattttca taatcttttt cttcaaaata tatacctgcc agattatttt ttgcttctgt
     4801 tatatcatct tcagcagcca ttttataata agtttttgcc ttctctatct cattttctct
     4861 attatataaa ttagcaagtc tatacttaga aagtgtatga tttttttcta ttgctttctc
     4921 ataataataa attgcatctc ccagctcttc ttttctatca tatacatatg caagcctata
     4981 ctcagacttc acatcatctc tatcagcact ctttttataa tacttctctg catcttctaa
     5041 attatcattt atttccataa tcatacccaa gttaaagcaa cctttcatat gacctgactt
     5101 gtacaactgt ttatataaac ttactgttga tttattatct ttcttttttc catttaatat
     5161 tgctaaatta tattttgcat catcatctaa aagcacagaa ccttttttat agtattcata
     5221 tgcttcatca tctttctcca aaaaagtata taatacccct aaattaaaac aagctttacc
     5281 taaattcttg tctgctgctg tttttaacca tttttcacac cttacaaaat ctttcatttt
     5341 aaaatggcat acacctaaat tattttgtgc ttgtaaataa cctaaatttg ctatcttttc
     5401 ataccaatat atagcatatt catagccatc taacttatag tacatattac ctaaatcaaa
     5461 agcagcatct tcacttccac ttttatatgc cattgaatac cacttttctg cttctttaaa
     5521 ttgtttttta ctttcatata tatttcctaa agtatattga gattttacgt aattatccaa
     5581 tgcagcactc ttatacaact ctattgcgct ttccatctta cccatctttt caaggagggc
     5641 acccttagta tgtacgactt tcgggtcatt agatatattt tttatttttt ttatagaaaa
     5701 ttttgtattt ttcattattc gctacctacc cattttataa aatatattct ctcaaacatt
     5761 attatacatt ataatctaca attaatgcta taatattgaa tttttacctt ttgtcactat
     5821 attgtaacat taaattttaa attttataat cattagattt tattatgtaa ttggtatata
     5881 atgtatatat aggggggaca ttttatgaat ttcagcaata tttttatcca agttgcagtt
     5941 ttatttataa ttattttagt tggatatttt gtcagaaaat tcaacttatt agatgaccac
     6001 tgcacatcta agctttcaac tttgacaatg acagtttttt taccatcaat gataattagc
     6061 tccatgcaaa ttaactttga tagtaaaatg atacaaaaaa tactattgtt attatttaca
     6121 tctttgatta tgtatatagt ttcaattata attgcatttt tattgaaata cattttaaaa
     6181 tgtaatgata aaaaagattt gggaatatac cagtatatag ttgttttttc aaatgttgct
     6241 tttatgggtt atcctgtaat tgaagcagtt ttaggtcatg aagcaatatt ctatactgca
     6301 atattcaatt tgccttttaa cttattttct ttcactttag gaatttatct tttatctaaa
     6361 ggcagtacaa gtagaggttt ttcaataaaa tcacttataa gccctgctac aatagctatt
     6421 gttattggac tttttttatt tgtaacagga cttaggttac cccaatttat aaacgagcca
     6481 cttgagatgt tgggaagtat aactacacca atatccatga ttatcattgg aagcttactt
     6541 gctaattctt cagctctcga ttgttttgtc aacaaaaaat tatatatagt cacttttata
     6601 agattattgg tacttcctgt gattgtgtat tttattctaa aaggatggat aaatgataag
     6661 atgattttag ctataccagt agtaatttct tcaatgcctg ctgctgcaaa tactgctata
     6721 atggctaatc aatatgactc caatataaca ctagcttcac aatgtgtgtt ttttacaaca
     6781 ctattttcag ttatatctat accttttata agtattttac tcttatcttg atttattttt
     6841 ttatgtatta tataataaca tattcaataa attacaaata taaacatttt attgtagtat
     6901 attgatggaa ttttttccta gatatttgtc aataatatct atatgtatta tagaatagga
     6961 ggcttaaata tggatatgga tttactcttt aaaatagtat ttgctatagt tgctataggt
     7021 gtttctgtaa aaatcattaa aactgttgct agtttagctt ttaaaatagc gttgatattg
     7081 ctaataattt tatttgtata tagaatgttt ttgtaaacat ttaaaaataa gttttttaac
     7141 acaatagaga agtaaaatag attatcttta atgtaaattt tttattaaag acactctatt
     7201 ttacttctct attagcttat ttaaattaaa tttttattat atcttcccat aatataaaca
     7261 tcttcaaatt ttccatctct gattacagca tattttttag ttccctctat ttcaaaacct
     7321 agctttttat ataaatttaa tcccttttca ttatccacaa ttacttctaa tcctactcta
     7381 gttaacataa tccaattatc tgctatatct aaaagttgtt ccataagctt cttacctact
     7441 cctcttccct gataattctc tgcaacactt attcctattt ctgcgctatg tctcaatcgt
     7501 ggagaagaat ttacatgtaa cccagcaaaa cctattacat ctttttctcc attattatta
     7561 gtttcagcta caaacatata atcattttct cccaaagaag ctaacatagc ttcagtttta
     7621 tcgactctgt cactcattaa tgccaaagta tttctcataa cactgtatgt tcttctaatt
     7681 tcattaaaag cttgtgcatc ttctcttctt ataggtctta ttgttatatc tataggctta
     7741 ctcatattgg attccccctc aaacataatc tttattttta attaaaattt tacatcttta
     7801 ttttatactg ttcaaatcta tgtatgcttc tacctgaggt acatatatca tattatcttt
     7861 tatatgtgta cttccaaatt cttttaattc tgtaccttct ttatccttag ttattttata
     7921 tctaatggat tccatacctt caactacttc agcatgaaaa aacatacctt catattgttt
     7981 aaatctaaaa ttaaaattgt ctttagtaag ttttattatc atatttttat ctactcctta
     8041 tataattgat atttttctta ttattagttg tatatatact gcttattcat attaatatat
     8101 tataacttat catttattta gtataaagtt ataaatagat atatttatac ttattttaca
     8161 atctttcttc aattgatata taatatgttt atataaacta atgtatgtga ggtgaaatat
     8221 gagcaaaaaa acaaaatatt tttctttaat tctctttcct attgctttgc ttttaaattt
     8281 tatagccagc aaagttccaa atattgttga aaaatattac tcccaattca tagataaaat
     8341 aattgtacaa atattgagta aagtttctgg aattttccca ttttctctct atgagattac
     8401 aatgtacata atagttatat ctatcttctt atttttatgt tgtactttat ctacaatttt
     8461 taataagaaa aaaaaattaa acatatattt aaaaaattcc attttaaata tattatccat
     8521 tgtatcaata gtctactttc tttttgtagt gctttgggga ataaactata ataggattcc
     8581 actagaaacc acacttataa ataactataa tttaaaaaac aatacctcta tccaatcaaa
     8641 acaatatagt gttaaagagc ttactaaatt atataaattc cttgtaatta aagcaaatga
     8701 aactagaaaa ctcacattac aagataaaaa tggtattgta aaatctaata cagattataa
     8761 tggtgtcata aatagagctc aactaggata cgataatatc ttggatatat tacctggtgt
     8821 tagtggtagt tattctaagc ctaagtatat tatttcatca aatctaatgt gctatacagg
     8881 aataactggt atatactttc cttttacagg tgaggcaaat gtaaatatag caatacctga
     8941 cttatatatt ccttgtacag ttgaacatga aatggcacat caaaggggat ttgctagtga
     9001 agatgaggct aattttatag cgtatcttac ttctataaaa caccccaata ttgattttaa
     9061 ctattctgga tatattttag ctttaaatta tactgcttct gctttaagta aggttgatta
     9121 taatgcatat gttgatattt ctgctggcat ttcagattct gtccgtagag atttaaaaaa
     9181 tgaaagtgaa ttttggcaaa aatatgaagg taaaattaat gaaatttcta atgagtttaa
     9241 caattcttac ttaaaagcta atagcgttac tgaaggtact cagagttatg gtaaaatggt
     9301 tgatttattg ctaacttatt atgaattata tccatataac taaacactac aattcaaaat
     9361 tttattcata tacagctgat attaaatcag ctgttttcta tttaaataaa ttatttaact
     9421 tcaagcaatc ttat
//
LOCUS       DAJMZY010000131         9396 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.133, whole genome shotgun sequence.
ACCESSION   DAJMZY010000131 DAJMZY010000000
VERSION     DAJMZY010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9396)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9396)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9396
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.133"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            <1..783
                     /locus_tag="OE968_003340"
     CDS             <1..783
                     /locus_tag="OE968_003340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HCP7220578.1"
                     /translation="IVDSNLDFMKATVNIIENIGIFIPMGIFLPIVCKNLNKKTIIIV
                     IILVSLAFELTQYIFALGSSDIDDVILNSLGGIIGINIYINMNKLFPNDINRFKAIIG
                     TSLVLGVIGLGVISKNYHNLLTFKFRPDRKISKILIEENREIIKDINKDTVDIVGTFE
                     SFKKGIITIKAGSNNKVKRPENLIDSDGNIRIYLNENTKLVSYIITKESKMDIVKYEE
                     FDVKNLDLLRRYDTINVWIDKENQPKDKHGIMASKLLIGLYE"
     gene            898..1683
                     /locus_tag="OE968_003341"
     CDS             898..1683
                     /locus_tag="OE968_003341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220579.1"
                     /translation="MEIIKYILYFFIYSFLGWTVESIGCSIASKRIINRGFLNGPICP
                     VYGFGAVIVISLLGRFNNVVIVFLLGMILTTILEYFTGFILETLFHAKWWDYSDKKFN
                     IKGRVCLKNAIYFGVMSVLIIRFIHPFIKYFVSIIPYRILISMAIITTLWTILDLIVT
                     IITLKKLDIKLNLLDDIITDLNDINVKLDKFDRGEIQALFKTINNDELEVREKINKIN
                     SKLDRIESNIILQKRVIKAFPHIKHKKQQEQLEHFKKIINEKR"
     gene            1975..3294
                     /locus_tag="OE968_003342"
     CDS             1975..3294
                     /locus_tag="OE968_003342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class III-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HCP7220580.1"
                     /translation="MSEITSQMISTEEKKYVAKTQKIPYYPVAFKSGDGAMLYDYEGN
                     EYVDFLASAGSANVGHGNKEISQAVKEQMDDITQYTLAYFHSDPPVKLAEKLVEIAPG
                     DNDKKVLYSATGSACIDAAIKLARGYTGRTKIISMCESYHGSTYGAISISALSTNMRR
                     KMGPLLPEVYHFHYPDKNRTAKECLDEIEYAFAHYLPAEEVAAIFIEPIAGDAGIIVP
                     PVEWVQGLSKICKENGILLVSDEIQQGMGRTGKWFGIENFGVEADLIVLGKSVGGGLP
                     LGAVVGRTEIMQSLDAPAHLFTLAGNTTVCVAALKSIEIIEKENLLQKSIEMGDYIKA
                     GFEKLKEKYDIIGEIRGIGLSIGVDIVKGKGSNEKHPDATAKICYRCIQTGLIMIFLG
                     QSTLRVQPPLVITKEQVDKAMNIIDSAIDDYLNGRIGDEVYEVTQGW"
     gene            complement(3369..3797)
                     /locus_tag="OE968_003343"
     CDS             complement(3369..3797)
                     /locus_tag="OE968_003343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220581.1"
                     /translation="MKDNNNTNKTIQFGEKKASLENNIQKNKNIKLDNTHKVIPYPKN
                     RKKDDKKKGNKKKNTNTSKVNKNNYGHSFFNNKYKYKRKPYVIALYTVILILLAILII
                     TKLTDSTNKGNYSRNTVSDTHKNDIRNIVFNESNNFLICG"
     gene            complement(3888..5264)
                     /gene="hydG"
                     /locus_tag="OE968_003344"
     CDS             complement(3888..5264)
                     /gene="hydG"
                     /locus_tag="OE968_003344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[FeFe] hydrogenase H-cluster radical SAM
                     maturase HydG"
                     /protein_id="HCP7220582.1"
                     /translation="MFINHELINSLLEDAKNSTSDDIEKVLDKADRREKLSYKDIATL
                     LEVEDKKQLDRLFSIAGQIKNEIYGNRVVLFAPLYVSNYCVNECVYCGFSKCNKFKRK
                     KLTMEEIREEVKILEKMGHKRLALEAGEDPKNCDINYILDCLDAIYSTYNENGNIRRV
                     NVNIAATSVDEYKLLKEKGIGTYILFQETYHKPTFIKMHGQSIKNDYYYHLTAFDRAM
                     EAGVDDVGAGVLFGLSDPKFEVLGLMMHNEHLEEKFGVGFHTISFPRLKKAEGMSLED
                     FPHLVSDDMFKKIVAITRLAVPFTGIIMSTRETAEMRNELLKYGVSQISAGSLTGVGG
                     YKAYEDGDNTEQFEVGDHRSPVEVLKELITDGYIPSYCTACYRKGRTGDRFMSLAKSR
                     QIHNVCTPNALTTLNEFLIDYGDEELKIMGKKLIAEEIGKIEREDIRNIVSNNMTALE
                     RGERDLYL"
     gene            complement(5265..6350)
                     /gene="hydE"
                     /locus_tag="OE968_003345"
     CDS             complement(5265..6350)
                     /gene="hydE"
                     /locus_tag="OE968_003345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[FeFe] hydrogenase H-cluster radical SAM
                     maturase HydE"
                     /protein_id="HCP7220583.1"
                     /translation="MTKNKIKYFIDKLYSINSLSFDELLYLIENIDNEEYNFEQNLRN
                     YLYKQASDMRNKHYGNRVYLRGLIELTNYCKNNCYYCGIQSSNKNIIRYRLSLDEILE
                     CCDIGYKIGYRTFVLQGGEDAYFTDDKICEIVSSIKNKYEDCAITLSLGEKSYDSYKK
                     YFLCGADRYLLRHETATDSHYKKLHPPNIELRTRKECLKNLKEIGYQVGAGFMVESPF
                     QNNEDLVRDLLYLKELNPHMVGIGPFIPHHDTIFKDYKHGDLEKTLLMLSITRLLLPK
                     VLLPATTALASINPSGRNAGLLAGCNVIMPNLSPQEFRKQYSLYDNKAFTGQEACEYH
                     QSLEENIKSLGLEVDYSRGDNIEWRRL"
     gene            complement(6386..7594)
                     /gene="hydF"
                     /locus_tag="OE968_003346"
     CDS             complement(6386..7594)
                     /gene="hydF"
                     /locus_tag="OE968_003346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[FeFe] hydrogenase H-cluster maturation GTPase
                     HydF"
                     /protein_id="HCP7220584.1"
                     /translation="MSLNSTPQSVRVHIGLFGKRNAGKSSIINAITNQSAAIVSDIAG
                     TTTDPVFRPMEILPIGPCVLIDTAGLDDVGELGELRIGKSLDVLEKTDIALLVVDCQI
                     GISQEDLSLIEKFNDKNIPHILILNKIDTIKNQSEILNLTKNKVKCPVVSVSSTDKIG
                     IENLKNEIIKVLPKDSTEFKLVSDLIEPNDLIVLVVPIDKAAPKGRLILPQQQVIRDI
                     LDSGAISIVTKEDSLKETLSNLGKKPKLVITDSQVFPQVDKDTPKDIPLTSFSILFAR
                     QKGDLKELINGAYALENLKDGDKILMAEGCTHHRQTDDIGTVKIPNMIRKKTGKNITF
                     EFSSGVSFTEDINKYALVVHCGACMMNRAGMLSRIEKAKSFNVPIVNYGILIAYVKGI
                     LERSLELFNY"
     gene            complement(7609..7860)
                     /locus_tag="OE968_003347"
     CDS             complement(7609..7860)
                     /locus_tag="OE968_003347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003361768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-only hydrogenase system regulator"
                     /protein_id="HCP7220585.1"
                     /translation="MKKVAVISAILEEPKECQFKFNEVVSGFKGIIKGRMGIPCEEEG
                     VSIVCIAVVGEMDTINSLTGKLGNIPHVSVKTSISKKEV"
     gene            complement(8241..9281)
                     /locus_tag="OE968_003348"
     CDS             complement(8241..9281)
                     /locus_tag="OE968_003348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HCP7220586.1"
                     /translation="MNLNLTNTINLMKKYLDIPSPAGYTENAVLEIKKDFENLGLDTI
                     LTKKGALIATLPGEDDSNQITISAHMDTLGAIVKEISSDGTLKYHKVGGGCWAAIEGE
                     NCTVITRKGKKIRGSVVFKYASTHIYGQTKAATERNEETMIIRLDEKVFTKQDVLDLG
                     ISVGDFVCLDHRFEATESGFIKSRYIDNKSAVAMVLEICRYFKENNLTPKHTTNFYIS
                     NYEEIGHGVSKCLPEKTKEFVAIDIAPTGPSQTSSEHGVTIVAKDNLSLYDFNLRNKL
                     VDVAEDNNLDYAVDVFTFYGSDASEAIRWGEDVQIACVGPGTNNSHHYERTHIEAIEN
                     TLKLLINYMLKE"
BASE COUNT         3341 a         1316 c         1331 g         3408 t
ORIGIN      
        1 atagtagata gtaatcttga ctttatgaaa gctactgtaa atattataga aaatataggt
       61 atatttattc ctatgggaat ttttttacct atagtatgta aaaatctaaa taaaaaaact
      121 ataattatag taattatact tgttagccta gcatttgaat taacacaata tatttttgct
      181 cttggaagta gtgatataga tgatgttatt ttaaattcat taggtggcat aattggaatt
      241 aatatttaca taaacatgaa taaattattt cccaatgata ttaacagatt taaggctata
      301 ataggtacta gtttagtttt aggagttata ggattaggag ttatttctaa aaattatcat
      361 aacttactaa cttttaaatt tagacctgat agaaaaatat caaaaatatt aattgaagaa
      421 aatagggaaa taattaaaga tataaataaa gatacagtag atatagttgg gacatttgag
      481 agctttaaaa aaggaataat aactattaaa gcaggttcta ataacaaagt aaagagacca
      541 gagaatttaa ttgattctga tggaaatata agaatttatt taaatgaaaa tacaaaatta
      601 gtatcttata taattaccaa agaatcaaaa atggatatag ttaaatatga ggaatttgat
      661 gtgaagaatt tagatttatt aaggagatat gatactatta atgtttggat tgataaagaa
      721 aatcagccaa aggataaaca tggtattatg gctagtaaat tattaattgg attgtatgaa
      781 taaaatatta aacaagaata aaagaataac aaatataaaa aacgaaaaaa ctatttctat
      841 aattattttt acgttgtgca taaaataaga acattagtga aggagtagag ataaattatg
      901 gagataataa aatatatctt gtactttttt atatattcat ttttaggatg gacagtagaa
      961 agtataggat gttctatagc aagcaaaaga ataatcaaca gaggtttttt aaatggtcca
     1021 atatgccctg tttatggttt tggagcggta attgtgatat cactattggg aagatttaat
     1081 aatgtagtaa tagtatttct attaggaatg attttaacta cgatactaga atattttaca
     1141 ggatttattt tagaaacctt atttcatgct aaatggtggg attattctga caaaaaattc
     1201 aatataaagg gtagagtatg tttaaaaaat gcaatatact ttggtgtaat gtctgtttta
     1261 ataataagat ttatacatcc atttataaaa tattttgtaa gtataattcc atatagaata
     1321 ttaatttcaa tggctataat tacaacactt tggactatac ttgatttgat tgttactatt
     1381 ataacactta aaaaattaga tataaagtta aacttattag acgatataat tacagacctt
     1441 aatgatataa atgtgaaatt ggataaattt gatagaggag aaatacaagc tttatttaaa
     1501 acaataaata acgacgaatt agaagttaga gaaaaaataa acaaaataaa tagtaagttg
     1561 gaccgtatag agtctaatat tattttacaa aaaagagtta taaaagcttt tccacatata
     1621 aaacataaaa aacaacaaga gcaactagaa cattttaaaa aaattattaa tgagaaaagg
     1681 taattataca atttaatgaa gacgaataga ataatggtat ttataagatg attttcagag
     1741 gactctataa aaatagaata gagtccttta ttttttgaaa aataatgttt atttgataaa
     1801 aataaaatat attgtttctg aataacaaat attttgaaaa ttataaaaac atatattgac
     1861 aatttgtgtc aaaaatacta acattaagta tataaagaat tttatatgag aatatcttta
     1921 taaatcgcaa taattttaaa acataaattt atttaaagag gggatgattt gccaatgagc
     1981 gagataacta gtcaaatgat aagtacagaa gaaaaaaaat atgttgctaa aactcaaaag
     2041 ataccttatt atccagtagc atttaaatca ggtgatggtg caatgctata tgattatgaa
     2101 ggtaatgaat atgtagattt tttagcaagt gcaggctctg caaatgtagg tcatggtaat
     2161 aaggaaatct cacaagcagt taaagaacaa atggatgata taacacaata tacacttgca
     2221 tatttccata gtgatcctcc tgtaaaatta gctgagaagc ttgtggaaat agcccctgga
     2281 gataatgata aaaaagtact atacagtgca actggttctg cttgtataga tgctgctata
     2341 aaattagcaa gagggtatac tggaagaaca aagataatat ctatgtgtga atcttatcat
     2401 ggaagtactt atggagctat atctatatct gctttaagta caaatatgag aagaaaaatg
     2461 ggtccattgt taccagaagt ttatcacttc cattatcctg ataaaaatag aacagctaaa
     2521 gaatgtttag atgagataga atatgctttt gcacactatc taccagcaga agaggtagct
     2581 gcaatattta tagagccaat tgcaggagat gcaggaataa tagtgcctcc agtagagtgg
     2641 gtacaaggtt taagtaaaat atgtaaagaa aatggaatat tacttgtaag tgatgaaata
     2701 caacaaggta tgggaagaac aggtaagtgg tttggtatag aaaattttgg tgttgaagca
     2761 gaccttatag ttcttggaaa atctgttgga ggtggattac ctctaggagc agttgttgga
     2821 agaacagaaa taatgcaaag tcttgatgca ccagcacatt tatttacttt agctggaaac
     2881 acaacagtat gtgtggctgc tttaaaatct atagagataa ttgaaaaaga aaacttactt
     2941 caaaagagta tagaaatggg agattatatt aaagcaggat ttgaaaaact aaaagaaaaa
     3001 tacgatataa ttggagaaat aagaggcata ggattatcta taggagttga tatagttaaa
     3061 ggaaaaggtt ctaatgaaaa acatccagat gctacagcta agatatgtta tagatgtata
     3121 caaactggat taataatgat attcttagga caatctactt taagagtgca accacctcta
     3181 gtaataacta aggagcaagt agataaagca atgaatatca tagattctgc aatagatgat
     3241 tatttaaatg gtagaattgg tgatgaagta tatgaagtaa ctcaaggttg gtaaaataaa
     3301 tattaaatga aaataggagt tatctcaatt ttagaaaatt atttctgaaa agagataact
     3361 cttttaagtt acccacaaat aagaaaattg tttgattcat taaagactat atttcggatg
     3421 tcgtttttgt gagtatcaga gacagtatta cgagaataat tacctttatt cgtactatct
     3481 gttaatttag ttataattaa gatagctaaa agaataagaa ttactgtgta taaagcaata
     3541 acatatggtt ttcttttata tttgtatttg ttattgaaaa aagaatggcc ataattattt
     3601 ttatttactt tagatgtatt tgtattcttt ttcttgttac ctttcttttt atcatccttt
     3661 tttctatttt tagggtaagg aatgactttg tgtgtattat caagtttgat atttttattt
     3721 ttttgaatat tgttttccag gctagctttt ttttctccaa attgaatagt tttattggta
     3781 ttgttgttat ctttcaatgt taatctccct cccttaaact ttccctttag ataatattac
     3841 tactaaccta tggaatatac aataaataat atataagtaa taaaatttta taggtataaa
     3901 tctctttctc cacgctctaa ggcagtcata ttgttagata ctatgtttct tatatcttct
     3961 ctttctatct tacctatttc ttctgcgata agttttttac ccataatttt aagttcttca
     4021 tctccataat cgattaaaaa ttcatttaat gtagtaagag catttggtgt acatacatta
     4081 tggatttgtc gacttttagc taagctcatg aatctatcgc cagttctacc tttacgataa
     4141 caagctgtac aataactagg tatatatcca tcagtaatca gttctttaag cacctcaaca
     4201 gggcttctat ggtctccaac ttcgaattgt tctgtattgt caccatcttc atatgcttta
     4261 tatcctccaa cacctgttag agaacctgca ctaatttgtg atacaccata ttttagtaac
     4321 tcatttctca tttcagcagt ttctctagtg gacattatga ttccagtaaa aggaacagct
     4381 aatctagtta tagctactat ttttttgaac atatcgtcag aaactaagtg aggaaaatct
     4441 tctaagctca taccttcagc ttttttcaat ctagggaaag atatagtatg gaaacctaca
     4501 ccaaattttt cctctaagtg ttcgttgtgc atcataagtc ctagaacttc aaatttaggg
     4561 tcagataaac caaataaaac tcctgcacca acatcatcaa caccagcttc catagctcta
     4621 tcaaaagctg ttaaatggta ataatagtca ttttttatag attgaccatg catttttata
     4681 aatgttggtt tgtgataagt ttcttggaat aatatataag ttcctattcc tttttctttt
     4741 agtaatttat actcatctac acttgtagct gctatgttaa cgtttaccct tcttatattt
     4801 ccgttttcat tatatgttga ataaattgca tctaagcaat ctaagatgta atttatatca
     4861 caatttttag ggtcttcacc agcttctaga gcaagtcttt tatgacccat tttttctaat
     4921 attttaacct cttcccttat ctcttccatg gtaagttttt ttcttttaaa tttgttgcat
     4981 ttactaaaac cgcaataaac acattcattt acacagtagt ttgatacata aagaggggca
     5041 aataaaacca ctctattacc atatatttca ttttttattt gcccagctat actaaataat
     5101 ctatctagtt gttttttatc ttctacttca agaagtgtag ctatatcttt ataactaagt
     5161 ttttcccttc tatcagcctt atcaagtacc ttttcaatat catcagaagt tgaatttttt
     5221 gcatcttcta ataaagaatt aataagttca tggtttatga acatttacaa acgcctccat
     5281 tcaatattat caccgcgaga atagtcaact tcaagtccta atgacttgat gttttcttct
     5341 aaactttggt gatattcaca agcttcttga ccagtaaagg ctttgttatc gtaaagagaa
     5401 tattgttttc taaattcttg aggagaaagg tttggcataa ttacattgca accagctaaa
     5461 agacctgcat ttctaccact agggtttata gatgccaagg ctgttgtagc gggtaataaa
     5521 acttttggaa gtagaagtct tgtaattgaa agcataagta atgtcttctc taaatctcca
     5581 tgtttataat ccttaaaaat tgtatcatgg tgtggaatga aaggtcctat tccaaccata
     5641 tgaggattta actcttttag gtataataaa tcacgaacaa ggtcttcgtt gttctgaaat
     5701 ggtgattcaa ccataaatcc agcacctacc tgataaccaa tttctttaag gttttttagg
     5761 cattcttttc tagttctaag ctcaatgttt ggcggatgta attttttata atgactgtct
     5821 gtagcagttt catgtcttaa aagatatcta tctgcaccac ataaaaagta ttttttatac
     5881 gaatcataac tcttttctcc tagtgataga gttatggcac aatcctcata tttatttttt
     5941 atacttgaaa caatttcaca tattttatca tcagtaaaat atgcatcttc accaccttgc
     6001 aaaacgaatg ttctgtatcc tattttataa cctatatcac aacattcaag tatttcatca
     6061 agtgaaagcc tgtatcttat gatattttta ttagaagatt gtattccaca atagtagcaa
     6121 ttatttttac aatagtttgt aagctctata agtcctctca agtagactct atttccataa
     6181 tgtttatttc tcatgtcgct agcttgttta taaagatagt ttcttaaatt ttgttcgaag
     6241 ttatattcct cattgtcgat attttctatt aaatatagta gttcatcaaa acttaatgaa
     6301 ttaatgctgt aaagtttatc tataaagtat ttaatcttat ttttagtcat attcaaatat
     6361 ataattatta agtatagtta aatttttaat aattgaaaag ttcaagtgat ctttccaaaa
     6421 taccttttac atatgctatt aagataccat agtttacaat aggtacattg aaagattttg
     6481 ccttttctat tctagataac attccagctc tattcatcat acaagctcca cagtgaacta
     6541 caagggcata tttatttata tcttcagtga aggatactcc agaactaaat tcaaaagtaa
     6601 tgtttttgcc agttttcttt ctaatcatat taggaatttt tactgttcca atatcatcag
     6661 tttgtctatg atgggtacat ccttcggcca tcaagatttt atcaccatct tttaaatttt
     6721 ctaaagcata agcgccatta atcaattctt taaggtctcc cttttgtcta gcaaacaata
     6781 tagaaaaaga tgtaagagga atatcttttg gtgtatcttt atctacttgt ggaaatactt
     6841 gagagtcagt aataacaagt tttggttttt tgcctaaatt agatagagtt tcttttaaac
     6901 tatcttcttt tgtaactata gaaattgcac cactatccaa aatatctctt ataacttgct
     6961 gttgaggaag tataagtcta ccttttggag ctgctttatc tattggaaca actaaaacaa
     7021 ttaaatcatt tggttcaatt aaatctgata ccaatttgaa ctcagtgcta tccttaggca
     7081 aaacttttat tatttcattt tttaaatttt caattccaat tttatctgtt gatgagacag
     7141 aaacaactgg acatttaact ttatttttag ttaagtttaa aatttctgat tgattcttaa
     7201 tagtatcaat tttgttgaga attagaatat gagggatatt cttatcatta aacttttcaa
     7261 ttagtgacaa atcttcttgt gatataccaa tctggcaatc cactactagt aaagctatgt
     7321 ctgtcttttc taaaacatct agtgatttac ctattctaag ttcaccaagt tcaccaacat
     7381 catcaagacc agcagtatct ataagaacac aaggtcctat aggaaggatt tccattggtc
     7441 taaatactgg gtctgtagta gttccagcaa tatctgagac tattgcagca ctttgatttg
     7501 ttatagcatt tattatgcta gatttacctg catttctttt accaaagaga cctatatgta
     7561 ctcttaccga ttgtggagta gaatttagac tcatttgtac tcaccacctt aaacttcttt
     7621 ttttgatata ctagttttta cagatacatg aggtatgttg cccaatttac cagtcaaact
     7681 attaatagta tccatttcgc caacaactgc tatacatacg attgagacac cttcttcttc
     7741 gcaaggaatg cccattcttc ctttaataat acctttaaaa cctgatacaa cctcattgaa
     7801 tttaaattga cattcttttg gctcttccaa aatagcactt ataactgcaa cctttttcat
     7861 aaatatcctc ctaactcaga aaatatgtct taaacaaatc caaaatcaaa aaacttttct
     7921 ttgtaaagaa aagtttctac aaaagaaaag ttattaatta cacaagtata atgtgctata
     7981 ttaaactatt tccttacaga ttagataact cttttctggt agggttagct tgtaaaaatt
     8041 taatttaaca acaagtaact gaagaaaatt tttatacaat ttatataaat tataataaaa
     8101 attaactaaa gaaaattgaa gttacttata taatagtagt aaattgaaat taagtctata
     8161 gaaaaaccaa tttttgtata aaaataaaaa ttaaagttaa ttatttgtta agaattgact
     8221 ttggtaaaat atataattaa ttattcttta agcatataat ttataagtaa ttttagtgta
     8281 ttttcaatag cttctatatg tgttctttca taatggtgac tattgtttgt tccaggacca
     8341 acacatgcta tttgaacatc ttctccccaa cgaatagctt ctgaagcatc tgaaccatag
     8401 aaagtaaata catcgacagc gtagtctaaa ttattgtctt ctgcaacatc aacaagcttg
     8461 tttcttaaat taaaatcata taatgataaa ttatcttttg caactatagt tacaccatgt
     8521 tcactagatg tttgacttgg tccagtaggt gctatatcta ttgctacaaa ttcttttgtt
     8581 ttttcaggta aacatttaga aacaccatgt ccaatttctt cataattact tatataaaag
     8641 ttagtagtat gcttaggtgt taaattgttt tctttaaaat atctacatat ttcaagaacc
     8701 attgctacag ctgatttatt atctatatat ctagatttta taaaaccaga ttctgtagcc
     8761 tcaaatctat ggtctaggca tacaaaatcc ccaacactta ttcctaaatc taatacatct
     8821 tgctttgtaa atactttttc atcaagtcta ataatcattg tttcttcatt tctttcagtg
     8881 gcagcttttg tttgaccata tatatgagta gaagcatact taaatacaac acttcctctg
     8941 atttttttac cttttctagt tataacagta cagttttctc cctctatagc tgcccaacat
     9001 ccaccaccaa ctttatggta tttaagagta ccatcagatg atatttcttt tactatagct
     9061 ccaagtgtat ccatatgtgc agatattgtt atttgatttg aatcatcttc accaggaaga
     9121 gtagctataa gtgcaccttt ttttgtaaga atagtgtcaa gacctaaatt ttcaaaatct
     9181 tttttgattt ctaaaactgc attttcagta tatccagctg ggcttggaat gtccaaatat
     9241 tttttcatta aatttatagt attagttaaa tttaaattca tattgtttcc tcctaaataa
     9301 atatatttat acaaattata acataaatac aaatgttctg aaaactaaaa ttaaaagaat
     9361 agaatctaaa catatttaaa aaaaaagtat ataaaa
//
LOCUS       DAJMZY010000132         9273 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.134, whole genome shotgun sequence.
ACCESSION   DAJMZY010000132 DAJMZY010000000
VERSION     DAJMZY010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9273)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9273)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9273
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.134"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            414..803
                     /locus_tag="OE968_003349"
     CDS             414..803
                     /locus_tag="OE968_003349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HCP7220587.1"
                     /translation="MEQQDVIDKLRRGELMLMEYLWNKKSILSKKEIIEAMKKRYKWR
                     KSTTEILLKRLVKMKTLKKKRIGFQFSYEVLVTKKEYLNARKEERDISKYDNFFARIF
                     TTIHKRDKMTEEQLKAFIKNMEKIGKI"
     gene            896..1276
                     /locus_tag="OE968_003350"
     CDS             896..1276
                     /locus_tag="OE968_003350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HCP7220588.1"
                     /translation="MGFKKLPDSELKVMKFIWGLEKKVASGEVVEAMKQTYGWNKNTT
                     LTILSKLAKKNYLYSQKTSKCTYYTIAVREKDYLKVETKKFFSFFHNNSLKSFFTALN
                     DEENLSDDKLDMLEEWVKNWEEDE"
     gene            1955..3385
                     /locus_tag="OE968_003351"
     CDS             1955..3385
                     /locus_tag="OE968_003351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HCP7220589.1"
                     /translation="MILNQIFIEAGGIMRNKIIIGITFSLVLLMSGCASKQTAEINVL
                     ATTDLHGVIPYELTSYVKEERKKDKNLTLVDAGDFFDSGEVFGSSMDSYFSARYKDGD
                     NNTESYIETPISKDMKEVGYDVAVLGNHEFISNNKFYLDNMISDFEKQKINILSANTY
                     KKNGDSYTKPYIIKNINTPEGNVKLGILGLTIKEVGERKQWKDGKLVDSKSLELKDQE
                     GYNGELYMNDLVEDAKKWVGIMEKEKPDIIVAVAHTGEKPKKPKNPGNRIQDLAQQVD
                     GIDAIVAGHNHVQIEQHDYKNKSGENVIVTEPGKHGECISKINFKLEKNNDKWNIVDK
                     SSKLIKFEKNQESDKFGEFISSINKVSKDKKEIRLSEVKTPEWDKIYVFKSGTSADDI
                     YKTIGYKWRNISSPKGDDMVQIVVMNNNKPVSYVYGEAEVMPINIKCDESEYKDNVVT
                     IYPNKNDKFKIEKGKQEYSINLKHIQ"
     gene            complement(3533..3883)
                     /locus_tag="OE968_003352"
                     /pseudo
     CDS             complement(3533..3883)
                     /locus_tag="OE968_003352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904812.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
     gene            3878..4399
                     /locus_tag="OE968_003353"
     CDS             3878..4399
                     /locus_tag="OE968_003353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HCP7220590.1"
                     /translation="MFSIGGGYAIILLIQEKVVNQTGWISEKMFTDIITISQMTPGPL
                     AVNTSTFVGLQIGGFWGAVAATLGCVLCGVVISLFLYNFFQKHQNSTYIFEILNGLKS
                     ASLGLIISAAATIIILALFGTNKVYFNSIFEMLNWTALIIFFVTLLIVRKWKINPIVI
                     IIISGILGIFFYL"
     gene            complement(4528..5322)
                     /locus_tag="OE968_003354"
     CDS             complement(4528..5322)
                     /locus_tag="OE968_003354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HCP7220591.1"
                     /translation="MIFCNSFITRKSSMNIVVTHTPIVTTLEMQKAYEPLAKHNVNIF
                     AFDFSGTGKSDGYEKDFSRNSIVKDLDSVITYIEKNYSSNIHLYGNTGIGGMFAQYYA
                     CSDNKLKSFAQFACVDYKNTTGVGYTYLTVKLLNFFFKFLPNFHITVKPPKYKGYNEV
                     YDNEFYKIFEKKNPHIWKNSTKIINTMLECFIAKDSKIKDGVNIPTLVFKTLHDRYFK
                     TQYFDSYYNSLKCKKKLVEINNVHNSYYIDSEKFCQEAYDWFVENQ"
     gene            complement(5546..8974)
                     /gene="uvrA"
                     /locus_tag="OE968_003355"
     CDS             complement(5546..8974)
                     /gene="uvrA"
                     /locus_tag="OE968_003355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HCP7220592.1"
                     /translation="MKINNYKNQSIITNPKKFENKYQDLPKTPIELLKVVQSLVIHGD
                     QGKLYGISFNKQQSDEELLRTIPQMLKRIFEINSNPLTIPRNPKQRLVGMCRDYSLLL
                     VSLLRYRGFEARMRAGFANYFESELTYEDHWLVEYYDTLTKRWIRIDAQIDDIQKNYF
                     QINFDTHDVGKTDGFLTGSEAWIRCRQGHAHQDDFGYNKNWKGWHSVKGNLLHDFNNM
                     IGLELLPWDLWTELSSKKYNQLTRAEKNLLDEMAEILSSGNIKIEDLNLLIEKLPEDY
                     LKSIFSQLKILGISEIKELGNPLELEKKFKFTKSINKSIKNSLCHNKSSIYLKGGRQN
                     NLKDVEVTIPKNQITVITGVSGSGKSSLAFDTIYEEGKRRYFENLSNGAKLSEQLQKP
                     EFDLLQGLTPTIAIEQKKGSQNPRSTVGTLTSIWDYLRMLFVSIGKSYCPYCKIPLEK
                     KNNTKNYCPHCQTIFSKINTSTFNANSHTGACHDCNGLGFTYQVNPQLIVKDPTISIL
                     DGATYYFGKLKGKKPNGNWMVGELYAIAKDKNIDLDIPWNELPRDFIDAILYGTDDKI
                     YEFSFESKGRESKIRRPASGAINHIQRLFRESSSENNTLHQYMNKIPCNTCGGELLCI
                     EARFTTIKGYRFPELTKMTIEQLWNWLCELPNQLQKNELSLVNDILTELKIRVSYLLK
                     VGLSYISTDRTAPTLSGGELQRVRLSSQLGSELVGLTYILDEPSIGLHPRDHNLIIKM
                     IEELRDKGNTVIVVEHDKDTILSADYIIDVGPSAGTKGGFIIAEGTTQEIIKNPNSIT
                     GKYLSTYNKISSQNKIIPSKWLSLKGCHANNLKNIDVEIPLNCMCSITGVSGSGKSSL
                     VFHSLLPALEEKLKQKSIPDKNYTEFTGFDAIDDFILMDQTPIGKSSRSTPATYINIF
                     DEIRSLFAETPQAKQKLLDESYFSFNSKKGQCPNCQGLGKTKIILQYMADQWVTCSEC
                     QGKRYQKEILSIQYKGKTIADILDMEVAEAKTFFSDCSDIYRKLSLLDEVGLGYLKLG
                     QNTLGLSGGESQRIKLAKELGTKTKKRMLYILDEPTTGLHFKDIENLLITFRKLVNEQ
                     HSLLIIEHNTEVIRASDWIIDIGPDSGINGGEIVASGTPDEIKINPNSITGHFI"
BASE COUNT         3315 a         1204 c         1379 g         3375 t
ORIGIN      
        1 agaaaaaata aaactatgaa tattagaaat atattttatt ttatctctaa gtatatatat
       61 tattagccac ctaaaaaact ttcacaaaaa caaaaagagt atatgttttt gataactgga
      121 tgatataact tataactcat tttacaattc ttagttcata tatatttatg ccactaaatt
      181 tctctagttt tgccgattta gttttattct acaactaaaa taatacaata gaattagtta
      241 ttattcaaca ggatagtttg aaagttgaat aattttatag aaatgaataa tattttacgc
      301 ttgaaaaaac agactaaata cgtagaatat ttggtaaaac ttacctgtat taattgcaat
      361 tagaaggttc tattattaat ttaaattaaa attaattcaa ggaagtgaca taaatggaac
      421 aacaagatgt aatagacaaa ctacgtaggg gcgaattaat gctaatggag tatttgtgga
      481 ataaaaagtc tattttatca aaaaaagaaa taatagaagc aatgaaaaag agatataagt
      541 ggaggaaaag tactacagaa attcttttaa aaagattggt aaagatgaaa acattaaaaa
      601 agaagaggat aggttttcag tttagctatg aagtattagt aactaaaaaa gaatatttaa
      661 atgctagaaa agaagaaaga gatataagta aatatgataa tttttttgca cgaatattca
      721 caactataca taaaagagat aagatgacag aagaacaact aaaggcattt ataaaaaata
      781 tggaaaaaat tggaaaaata taatttatat atatcaatta attttaaatt aaatttgtta
      841 taatatttat atatatttta atatgcagaa atttacaaaa aagggggtgc atattatggg
      901 atttaaaaaa ttacctgatt cagaattaaa agtaatgaag tttatctggg gattagaaaa
      961 aaaagtagct tcaggagaag ttgtagaagc tatgaaacaa acttatggtt ggaataaaaa
     1021 tacaacacta acaatattgt ctaagcttgc aaagaaaaac tatttgtatt ctcaaaaaac
     1081 aagcaagtgt acatattata ctatcgctgt aagagaaaaa gattatttaa aagttgaaac
     1141 aaaaaaattc tttagttttt ttcataataa ttctttaaaa agttttttca ctgctttaaa
     1201 tgatgaagaa aatttaagtg atgataaatt agatatgtta gaggaatggg tgaaaaattg
     1261 ggaagaagat gaataaaatg aatgtgatac taaaatgata ctaatatgtt ttatagcgtg
     1321 ttaaaaaata tagaaaatat agaaataata gaagaaaatt aatgtaatag ataaggtttt
     1381 atcagattaa aaagaaaatc aatagaatgg gaataaaata tagaatgcca aaaatccaca
     1441 taaatacagg atttgaggtc tctcttactt ctatgttata ctggtttgat actatcaata
     1501 tttgccagta tcttatggat taataagcaa aaaacatcct gctgaatgat aaattcagcg
     1561 gggtgttttt attttgtttt agaactcctt tgctctgaaa ctcgaagtat ttaacactga
     1621 tgattttgtt atcttttagt tccttttgtg tcatgctctg aaagacaaat tgatacaata
     1681 aaaaagtaat ttcttaatca ttgatggaga tatgtgttta tgttactctt gatggtaatt
     1741 tgagtaatat tgttcatagc tttttatatt cacttaatta gaaaaccatt tggtataatc
     1801 ataaataaac ttgatgatat aatagaaaag atttataatt attagaagta tataaaagta
     1861 ttttatgtct atgaaatgta tgtctataaa acatatagat gacttttgta tattaatgta
     1921 tgaatattga tattatagaa gaattgagtt gtcaatgata ctaaatcaaa tatttataga
     1981 agctggaggg attatgagaa ataaaataat tataggaatt actttttcac ttgtattact
     2041 aatgtctgga tgtgcttcaa aacaaaccgc agaaataaac gtattagcaa ctactgattt
     2101 acatggagtt ataccttatg agttaacttc ttatgtaaaa gaagaaagaa aaaaagataa
     2161 aaatctaact ttagtagatg caggagattt ttttgatagt ggagaagtgt ttggttctag
     2221 catggatagt tattttagtg ctagatataa agatggtgat aataacactg aaagttatat
     2281 tgagacgcct atttcaaaag atatgaaaga ggtaggttat gatgttgcag ttcttgggaa
     2341 tcatgaattt atatccaaca ataaatttta tctagataat atgatatctg attttgagaa
     2401 gcaaaaaata aatattttat cggcaaatac gtataaaaaa aatggagata gttatacaaa
     2461 accatacata ataaaaaata ttaatacacc tgaaggaaac gtaaaactag gaattttagg
     2521 gcttactata aaagaagttg gtgagaggaa acagtggaaa gatggaaaac ttgttgactc
     2581 taagtcttta gaactaaaag accaagaggg ttacaatggt gaattgtata tgaatgattt
     2641 agtagaagat gctaaaaagt gggttggtat aatggaaaaa gagaagcctg acattatagt
     2701 tgctgtggca catacaggtg agaaacctaa gaaacctaaa aacccaggaa atagaataca
     2761 agacttagct caacaagttg atggaattga tgctatagtt gcaggtcata atcatgttca
     2821 aattgagcaa catgattata aaaataaatc aggagaaaat gttatagtta ctgagccagg
     2881 aaagcatggg gaatgtattt ctaagattaa ttttaaatta gaaaaaaaca atgataaatg
     2941 gaatatagtt gacaaatcta gtaaattaat taaatttgaa aaaaatcaag aaagtgataa
     3001 atttggagaa tttatttctt caattaataa agtaagtaaa gataagaaag aaataagatt
     3061 atcagaagta aagactcctg aatgggataa aatatatgtt tttaaatctg gaacatctgc
     3121 agatgatata tataaaacaa taggatataa atggagaaat atatcatctc caaagggtga
     3181 tgacatggtg cagattgttg taatgaataa taataagcct gttagctatg tatatggtga
     3241 agctgaagtt atgccaatta atataaaatg tgatgaatca gagtataaag ataatgttgt
     3301 aactatttat cctaataaaa atgataaatt taaaattgaa aaaggtaaac aagaatatag
     3361 tattaattta aaacatatac aatagaaact tttatcttat ttaagtttag attgtactta
     3421 aaataaagtg tgtattattt taaaaattga tgataattaa aatcacaaca ttaaagaata
     3481 gtacacactt tttatgctaa aaaatagaat gttaaaaaat taaaccttta aattaaagta
     3541 cattgcttat attatccaat attattttca aaggttgtgt aatattttta tccttatgta
     3601 atattgctaa cattttattt tccatatcta tcccatctaa ttcaatcaat cgcaattttt
     3661 tatgtaagag tgaatctaat aataaatttt ctggcaaaat ggttatacct aaccctgctt
     3721 gtgcagcttt aataagtgca aaagaattaa cactttccca aacaggataa gctttttggt
     3781 ttgaaagaga taatacactg tccaaagtat tgcgaatggc acttccttgc tcacgtaaca
     3841 ataacggaaa cgtgcataac tgtcgtagag ataaggcttg tttagtattg gtggtggtta
     3901 tgcaatcata cttttaatcc aagagaaagt agtaaatcaa actggatgga taagtgagaa
     3961 aatgtttaca gatattataa ctatttcaca aatgacacca gggccactgg ctgttaatac
     4021 ttctactttt gttggacttc aaattggagg gttttgggga gcagttgcag ccactttagg
     4081 ttgtgtatta tgtggtgtag taatatctct atttttatat aatttttttc aaaagcatca
     4141 gaactctact tatatatttg aaatattaaa tggtctaaaa tcagcttcat taggtttaat
     4201 tatctcagct gcggctacaa ttataatcct tgcattattt gggacgaata aagtgtactt
     4261 caattctata tttgagatgc taaactggac tgcactaata atcttttttg ttacactact
     4321 gatagtacgt aagtggaaaa ttaatcctat tgtgattata ataataagtg gtatactggg
     4381 aatatttttt tatttataag tttttggtaa gtagaggata tctatttttt tatatcttaa
     4441 atccaaatag ccaataaagt aaggccattt ggatttttaa taaattctga aaagataatc
     4501 agaaacccat ataacattta aattatatca ctggttttct acaaaccaat cataagcttc
     4561 ttggcaaaat ttctcactat ctatatagta actattatga acattattaa tttcaacaag
     4621 tttcttttta cattttagtg aattataata gctatcaaaa tattgggttt taaaatatct
     4681 atcatgaagt gttttaaaga caagagtagg tatgttgact ccatctttta tcttactatc
     4741 ttttgcaata aagcattcta acattgtatt aattatcttt gtactatttt tccaaatatg
     4801 aggatttttc ttttcaaata ttttataaaa ttcattatca tagacttcat tataaccttt
     4861 atatttaggt ggttttactg ttatgtgaaa attaggaaga aacttaaaga aaaagtttaa
     4921 taatttaaca gtgagatagg tatagcctac tcctgttgtg tttttataat caacacaagc
     4981 aaactgagca aaacttttta acttattgtc tgaacatgca taatattgtg caaacatacc
     5041 accaattccc gtattcccat atagatgtat gttggaagaa taattttttt ctatgtatgt
     5101 aatgacagaa tctaagtctt ttacaattga attgcgagaa aaatcttttt catatccatc
     5161 acttttccct gttcctgaaa aatcaaaagc aaatatattt acattatgtt tggcaagtgg
     5221 ttcatatgct ttttgcatct caagcgtagt gacaatagga gtatgtgtaa caacaatatt
     5281 catggatgat tttctggtaa taaatgagtt acaaaaaatc attgtatctc catttggtat
     5341 ttttatatgt ttccaactca tttgattttc ctttctctat tataaaatat aataattttt
     5401 atgttctgtt ttatatatta ttcatatttt atcacagata atatactaaa gttaattttt
     5461 ttattgtaca cctattataa taattcttct ataatataag acattctata attttatatt
     5521 taagttcatg tgtatttaat tgtttttata taaaatgtcc agtaatacta tttggattta
     5581 tttttatttc atcaggagtt ccagaagcaa caatttcccc tccatttatt ccactgtctg
     5641 gacctatatc gataatccaa tcagaagcac gtataacctc tgtattgtgt tcaataatta
     5701 aaagtgaatg ctgttcattt acaagttttc taaaagtaat taacaaattt tctatatctt
     5761 taaaatgaag tccagtagta ggctcatcca atatgtacag cattcgtttt ttagtttttg
     5821 tccctaattc ttttgctaat tttatccttt gagattctcc tccacttaat cctaatgtat
     5881 tttgtccaag ctttagatat ccaagtccca cttcatctaa taaggagagt tttctatata
     5941 tatcagagca atcgctaaaa aatgtttttg cttctgctac ttccatgtca agtatatctg
     6001 caattgtctt tcccttgtat tgtatagaca gtatttcttt ttgatatctc ttaccttgac
     6061 attcactaca agttacccat tggtctgcca tatattgcag aataattttt gttttaccta
     6121 atccttgaca gtttgggcat tgcccctttt tgctattaaa gctaaaatag ctttcatcca
     6181 ataatttttg ttttgcttgt ggagtttcag caaatagaga acgaatttca tcaaaaatat
     6241 tgatatatgt agcaggtgta gaacggctag attttccaat aggtgtttgg tccattaaga
     6301 taaaatcatc aatagcatca aatccagtaa attcagtata atttttatct gggatagatt
     6361 tttgtttcaa tttttcttct agagcaggaa gtaaactgtg aaatacaaga gagctcttac
     6421 cagaaccact aacacctgta atagagcaca tacagtttaa gggaatttct acatcaatat
     6481 tttttaagtt atttgcatgg catcctttta agcttaacca tttacttggt ataattttat
     6541 tttgtgaact tattttattg tatgtgctta aatatttacc tgttatagag tttggatttt
     6601 ttataatttc ttgggttgta ccttctgcaa taatgaaccc cccttttgta ccagcacttg
     6661 ggcctacatc aataatataa tcagcagaca gtattgtatc tttatcgtgt tccacaacta
     6721 taacagtatt acccttatct cttagctctt ctatcatttt gatgattaaa ttatggtctc
     6781 ttgggtgtaa accaatagat ggttcatcta aaatgtaggt taagcctact aattcacttc
     6841 ctagctgact tgataatcgt actctctgca gttctcctcc agataaagtt ggagctgttc
     6901 tatctgttga tatatagcta agacctacct ttaatagata actaactcga atttttaatt
     6961 ctgttaagat atcatttacc aaagagagct catttttttg aagttgattt ggtaattcac
     7021 acaaccaatt ccataactgt tctatcgtca tttttgttag ttcagggaag cgataacctt
     7081 tgattgtagt gaatctagcc tcaatgcaca gcaattcgcc accacatgta ttgcaaggaa
     7141 ttttgttcat atattgatgc aaggtattat tttcagaact agattctcta aaaagtcttt
     7201 gaatgtggtt gattgctcct gaagcaggtc ttctaatctt tgattctcgt ccctttgatt
     7261 caaagctaaa ttcatatatc ttatcgtctg taccatataa gattgcatct ataaaatctc
     7321 ttggtaattc attccaaggt atatctaggt ctatattttt atcttttgct attgcatata
     7381 attcacctac catccaatta ccatttggct ttttcccctt caattttcca aaatagtaag
     7441 tagctccatc taatattgaa atagttgggt cttttacaat caattgagga ttaacttgat
     7501 aggtaaaacc taatccatta caatcgtgac aagctccagt atgggagtta gcattgaagg
     7561 ttgaagtatt tatcttagaa aaaatagttt gacaatgtgg acaataattt tttgtattat
     7621 tctttttttc taatggaatt ttacaatatg gacagtaact ttttccgatt gatacaaata
     7681 acattcttaa ataatcccaa atgcttgtaa gagtaccaac agtagagcga ggattttggc
     7741 ttcctttttt ctgttcgata gctatagtag gggttaatcc ctgaagtaaa tcaaattccg
     7801 gtttttgaag ctgttctgaa agttttgctc cattacttag attttcaaaa taacgtcttt
     7861 ttccttcttc ataaatcgta tcgaaagcta aagaagattt tccactacca cttacacctg
     7921 taataacagt tatttgattt tttggaattg taacctcaac atcctttaaa ttgttttgcc
     7981 ttcctccttt taaatagata gagcttttat tatgacaaag tgaattttta attgatttat
     8041 ttattgattt tgtaaatttg aatttctttt cgagttcaag aggattgcct aattctttta
     8101 tttccgaaat gcctaatatt tttaactgag aaaagattga tttcaaataa tcttcaggca
     8161 atttttctat taacaaatta aggtcttcta tttttatatt tccgcttgat aatatttctg
     8221 ccatttcatc taataaattt ttttctgctc ttgttaattg attgtatttt ttggaactta
     8281 attctgtcca taaatcccat ggaagcaatt ctaaaccaat catattatta aagtcatgta
     8341 gaagattacc ctttacagaa tgccaacctt tccaattttt attatatcca aagtcatctt
     8401 gatgagcatg tccttgccga catcttatcc aggcttctga accagttaaa aaaccatctg
     8461 tttttccgac atcatgagtg tcaaaattaa tttgaaaata atttttttgt atgtcatcta
     8521 tttgtgcatc tattcttatc catctctttg ttagagtatc atagtattct acaagccagt
     8581 ggtcttcata agtaagctca ctttcaaaat aattagcaaa acctgctctc attctagcct
     8641 caaaacctcg atatcttagg agcgatacaa gaagtaaaga ataatctctg cacattccaa
     8701 caagcctttg ttttgggttt cttggaatag ttagtgggtt agaatttatt tcaaatattc
     8761 tttttaacat ttgaggaatt gtacgaagca attcctcatc agattgttgt ttattaaagg
     8821 atataccata taattttcct tggtctccat gaattactag gctttgaacc acttttaata
     8881 actcaattgg agtctttggt aaatcttgat atttattttc aaatttttta ggatttgtga
     8941 tgatgctttg atttttatag ttatttattt tcatttatat ttcacctctc taaatggatg
     9001 atataccctg acatggtgtc atatgcaagg gcaatttaaa ttttttggcc aaaatttaaa
     9061 aataaataaa aaatgataca gtgataaatt gtaatacaaa tatagtttca aattgcatat
     9121 aatataatta tttaataaaa ccattatcta tggaatgtta atgaaatgtt aagatggcat
     9181 tcttgaatat taagaaatag aatactataa tatagtgtga aggattttta gtaaaaaaat
     9241 ttgtaagtgt taatatacat taaaaaatag att
//
LOCUS       DAJMZY010000133         8960 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.135, whole genome shotgun sequence.
ACCESSION   DAJMZY010000133 DAJMZY010000000
VERSION     DAJMZY010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8960)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8960)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8960
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.135"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            275..924
                     /locus_tag="OE968_003356"
                     /pseudo
     CDS             275..924
                     /locus_tag="OE968_003356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429361.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase family
                     protein"
     gene            1465..2820
                     /locus_tag="OE968_003357"
     CDS             1465..2820
                     /locus_tag="OE968_003357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HCP7220593.1"
                     /translation="MDTKISINENMSLGKRFFKYLAPSVVAMWVFSLYTMVDGIFVSK
                     GVGELALAAVNISMPFINFIFAVSLLFSTGASTIIAIYLGKKDIKSANEVFSFNLVSI
                     IILSIIILAITFFNLDRLALFLGATESTIGMVKDYLGIIIFFNGFFIVSYSLEVIIKT
                     DGFPILATVGVIISALTNIILDYLFVIEFGWGVKGAGIATGLSQVFSTIFFLIHFLRK
                     NSTLNFSKFRIDFKTLRKIVFIGFPDSTTELSCGIVVLLFNLSLTKYIGENALIYYSV
                     INYINTLVLMTMMGITQGMQPLTSFYYGAGNIDNVKKLLKMGIKATIIASVAVFAICM
                     AFSGPIVSLFIHPEETMLFNEGVRVFKIFSISFLLVGINVIISGFFVSVEKPSISTVI
                     SLGRGLVIVVLSLISMILIFGGQGIWMTTIVSEFICLILSLVFLKKNFSTLDSNLNKV
                     A"
     gene            complement(2938..3606)
                     /locus_tag="OE968_003358"
     CDS             complement(2938..3606)
                     /locus_tag="OE968_003358"
                     /EC_number="6.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphthine--ammonia ligase"
                     /protein_id="HCP7220594.1"
                     /translation="MKEVLKLADEKFVMSFSGGKDSILALNRMLKKGYKPVALLTTIS
                     EEHGKSWTHNLEYNMLKQVSSNIGLPLLVAECGVEGYEESFERALIKAKNMGATICAY
                     GDIDIESHRKWDTDRCEAVGMKVDLPLWQESREDLVYEFIDSGFCSVVTKVNLKHLGE
                     EFLGKKLTRELVEKIKNAGADPCGEHGEYHTFVVDGPIFKKPVEYEVKGTLIKDGYGY
                     LEIK"
     gene            complement(3673..4101)
                     /locus_tag="OE968_003359"
     CDS             complement(3673..4101)
                     /locus_tag="OE968_003359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HCP7220595.1"
                     /translation="MTKLWAIIFALLAGGSTALEAFINGELGKSTTALVATFISLTVG
                     AIFFLASIIVTGDLKCLVSINGFNYKLLLGGVFGGLIIYFTVKAIPNLGVSNTLILTL
                     VSQVLVGFFIDSVILGQETMHLYKYIGVILLILGTFFIVN"
     gene            4208..4801
                     /locus_tag="OE968_003360"
     CDS             4208..4801
                     /locus_tag="OE968_003360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HCP7220596.1"
                     /translation="MNFCYNCSIDFGGDFMYTNFNIDFNNFNKKENAIKFMLMGVLLI
                     ILGLLCLTFKTLGIKLISWTFGIALLFFAYLNLKNINELKRYATKEEIKPSINIQWVL
                     IIACILLFVFPQKIQSIFSLFLGFYLIFNQLVALVNSKNNPYSKFTTWNIVKILFGIC
                     LILSPLFLSRFIVSIMSFFIILFGLVLFFSGNTARKY"
     gene            4920..5855
                     /locus_tag="OE968_003361"
     CDS             4920..5855
                     /locus_tag="OE968_003361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893027.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HCP7220597.1"
                     /translation="MDKFKYAFDNKRYHTWNYYLRNTFGEKVFKVSINAGFTCPNIDG
                     SLGYGGCTYCSKEGSGDFAGNPKDNLISQFYNIKEMMLKKWPHAKYIGYFQAYTNTYA
                     PLEVLKEKYETILELEDVIGLSISTRPDCLPDDVVEYLSELNKRTNLWVELGLQTIHD
                     STSKIINRGHDYKTFVEGVEKLKSKNIKVVVHIINGLPGEDYNMMMETAKAVGKMGVD
                     GIKIHLLHVIKDTPMEKMLQNGMLTLMEQDEYINLVCDQLEILPETMIIHRLTGDGKR
                     DELVGPIWSLKKWEILNQIDDTLKARNSYQGCKFV"
     gene            complement(6126..7070)
                     /locus_tag="OE968_003362"
     CDS             complement(6126..7070)
                     /locus_tag="OE968_003362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HCP7220598.1"
                     /translation="MGEKSKGYVFIAIAGLLWATLGLFGKFLMGNGLTSEQVAFTRLF
                     FGFIVLGVYSSIRTPQILKISKKGIIYSVIIGIICQAMFNLCYFKAIDIAGVSIAAVL
                     LYTSPLFLAIFSKICYKENITRSKLFSLILCFIGAIMAVTGGRLDFQGLNAFGLLLGV
                     LSAIAYALMPTISKNALKEFSSSTILVYSFLFGAIFMIPSSRPWEILNYAKDLDVLSC
                     MLMLGIVPAALAYIFYAAGISKGVELSVAGVVASVELVGSVIIGCTILGESFSLGKLF
                     GVMLMLISAVVALNLSYDEIRIFYKSNKLKQIEKTESI"
     gene            7388..8818
                     /locus_tag="OE968_003363"
     CDS             7388..8818
                     /locus_tag="OE968_003363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HCP7220599.1"
                     /translation="MNLDLEFYQKILEASHDEICVSDDKGIIIYCNKAFEENYGLKKE
                     DILGKNVSFLEDSGYSTKSPIPIVLKTKTKFSLEQDTQTGKKLIITATPIFDENGNLE
                     FTVENCRDITELNNIKNKLEDTKKQVKKYKSEVETLYRTALRIEDTVIMDGIVMRPII
                     NTVNHVSKTDVSVLLLGESGTGKSSLARYIHHNSNRSNGPFITINCATISPQLLESEL
                     FGYTSGAFTGASTKGKVGLVELANGGTLFLDEIGDIPQNLQAKFLQLIQDRTFTPVGS
                     LKNKKVDIRIISATNVDLVSKVKEKKFREDLYYRLNVIEIKLPPLRERRDNLVEIIKY
                     YFNRYSSDFNLNKTISKEAMDAIANYRFPGNIRELQNIIQKILLTCTDNHITIDDLPN
                     ILTKNIHITNNGNKTHISQINKVIISDSKSTNYKNKNFDTLIKEYEKNIILDAYEKFG
                     SSYKVAKHLEISQSKANRLIRKYTNT"
BASE COUNT         3326 a         1255 c         1125 g         3254 t
ORIGIN      
        1 attcattaaa aaatccattt ttatttacaa tcttatatcc ctttgcatct ctttctaaat
       61 actcttccta aatactcttc aaaactttca tcatctaatc taaatcctat atcactatga
      121 aaaataggtt ttgcatttgg atatagttct attgttttat caaaagtttc gaataccaag
      181 ttattattat tcgattttcc aacagtccac tataaacaat aataagtttg ttgctccaaa
      241 taatgtaaca cttgtagaaa gatgttacag atatataaaa gatagagaat gtagtttttc
      301 tcctaatact attagaaata gaaaaaatat gattaaaaat caaattgaag ttttctttaa
      361 agatatgaaa ttaatagata taactccttc tattttacag tcttatataa ataacatata
      421 caatgagcac atgttaaatt caacaaaaaa ccaagtcgat tttataaaat cagtattgaa
      481 agaatcttat agattaaaag aaatatcaga aaatatttgt gattttgtta caaccccaat
      541 caaaaaaaat agttcaactt ctaagcttta tacaaaacaa aaagctcaat tattattaga
      601 aaaatcaaaa aatattccta taggtatacc aatttttttg atgctaactc ttggattacg
      661 ttttggtgaa gctgtatcac ttatatggtc agatgtagac cttgataaaa aatctcacat
      721 gtaaatcaaa cattagttta tgtatacaat aaaataatct tcaaaggccc taaaacccct
      781 agattcaaaa gaagattatt tgttcctgat gaacttataa gtttgtttaa aggggaaaaa
      841 ttaaaacaaa ataagttaaa attacagggt atattgaaaa atgaatttga tttgatatgc
      901 ttaaataaaa gattcaaccc gtgagttcaa ccaacttttg ttgttcattt taaaaaacta
      961 ttaagagata ataatcctag agatataaaa gtacatgaat taatacatgc aaatgcgact
     1021 ttgatattac tttcaggtac taacataaaa gctatttata aaatattagt acatgcagat
     1081 ataaaaatag ctatgaatat atattccata ttctcactta ttagatgaaa tgaataaaga
     1141 aacatctgaa aatataagca aaatactatt caaataatgt tcagttttat gtcaattaaa
     1201 tgtcactcaa agtgcttttt ttccatttgt cagttaaatg tcacttaaag tacctttttc
     1261 ctatttgtca gttaaatgtc agtaatatat aaataagata tatttataag acccttaaaa
     1321 tcactattat ttaataaaat ttataattat atactatttg ctgttgacat tggtattata
     1381 ccatagttta tcatttatat tagaataaaa ttattaatta atagtttcgt aattttataa
     1441 tagatttaca gggagtgata ataaatggat acaaaaatat ctataaacga aaacatgagt
     1501 ctaggtaaaa gattttttaa atacctagca ccatctgtag ttgcaatgtg ggttttctca
     1561 ctatatacaa tggttgatgg aatatttgta agtaaaggag ttggagaatt agctttagct
     1621 gctgtcaata tatcaatgcc ttttattaat tttatatttg cagtttctct attattttca
     1681 actggtgcat ctaccataat tgcaatctat ctggggaaaa aagatattaa atctgctaac
     1741 gaagtctttt catttaactt agtatcaata attatattat caataattat attagctata
     1801 acttttttta atttagatag attagcacta tttttaggag ctacagaatc tacaattggt
     1861 atggttaaag attatttagg aataataata ttttttaacg gattctttat agtgtcttat
     1921 tctttagaag ttataataaa aactgatggc tttccaatat tagctactgt tggtgtaata
     1981 atatctgctc ttacaaacat catacttgat tacttgtttg taattgaatt tggatggggt
     2041 gtaaaaggtg ctggtattgc aactggtttg tctcaagtct tttctactat tttcttctta
     2101 atacattttt taagaaaaaa ctctactttg aatttttcaa aatttagaat tgattttaag
     2161 acacttagaa aaattgtatt tataggtttt cctgattcaa ctactgaatt aagttgtggt
     2221 atagttgttt tactttttaa cttaagtctt actaaatata ttggagaaaa tgctcttatt
     2281 tattatagtg tcataaatta tataaataca ttagtactta tgactatgat gggtataact
     2341 caaggtatgc aaccacttac tagcttttat tatggtgcag gaaatataga taatgtaaaa
     2401 aaattattaa aaatggggat aaaagccaca ataatagcat cagttgctgt atttgcaatt
     2461 tgtatggctt tttcaggacc aatagtctct ttatttatac atccagaaga aacaatgcta
     2521 ttcaatgaag gagttcgtgt atttaaaata ttctctatat ctttcttatt ggtaggaatt
     2581 aatgtaataa tttctggatt ctttgtatca gtagaaaaac catcaatttc tactgttata
     2641 tctcttggta gagggcttgt aatagttgtt ttaagtctaa tttcaatgat actaatattt
     2701 ggtggacaag gaatatggat gactactatt gtttctgagt ttatatgtct tattttatca
     2761 ttagtttttc taaaaaagaa tttttctaca ttagactcta atctaaataa ggttgcttag
     2821 atgataagag tgacaatata tgaaaatatc taaataaaaa atacctatta tacaatcttg
     2881 caaatattaa acctttgcaa aaattaggat tatataatag gtattttatt tatgtaatta
     2941 ttttatttct aaatatccat agccatcttt tattaaagtt ccttttactt catattctac
     3001 aggtttttta aatattggac catctacgac aaatgtatga tactctccat gttctccaca
     3061 tgggtctgca ccagcatttt ttatcttctc cacaagttct ctagttaatt tttttcctaa
     3121 aaattcctct cctaagtgct ttaagtttac ttttgttaca acactacaaa atccactgtc
     3181 tataaattca tatactaaat cctctctact ctcttgccat aatggtaaat ctactttcat
     3241 accaactgct tcacatctat cagtatccca ttttctatga ctttctatat ctatatctcc
     3301 atatgcacat atcgttgctc ccatgttttt agcttttatt aaagccctct caaagctctc
     3361 ttcatatcct tctacgccac actcagcaac taataaaggt aatcctatgt tgctacttac
     3421 ttgcttaagc atattatatt ctaaattatg tgtccatgac tttccatgtt cttcacttat
     3481 agttgtcaag agtgccacag gcttatatcc ttttttcaac attcgattta atgctaatat
     3541 actatcctta ccaccactaa atgacattac aaatttttca tcagccaatt ttaacacctc
     3601 tttcatctaa ctttgtttta ttaacataat tataccaaat ttttgagttg catagcaaat
     3661 tatattaaat tgttaattca ctataaagaa tgtccctaat attaaaagta taacccctat
     3721 gtatttgtat aaatgcattg tttcttgtcc caaaattacg ctatcaataa aaaatccaac
     3781 taaaacttgg gatacaagag ttaatataag tgtatttgat actcctaaat ttggaattgc
     3841 ctttactgta aaatatatta ttagacctcc aaatactcct cctaataaca acttataatt
     3901 aaaaccattt atagatacta gacactttaa gtcacctgta actattatac ttgccaaaaa
     3961 aaatattgct cctacagtta agcttataaa ggtggccact aatgctgttg tactttttcc
     4021 tagctctcca tttataaaag cttcaagagc tgtagaacca cctgctaata atgcaaatat
     4081 tattgcccat aattttgtca tggacaaacc tccttctata taattctatt aatagaagtt
     4141 tatgatacaa cctattaatt aattactaag tatagtttaa tttttataca ctaggcttta
     4201 tttggatatg aatttctgtt ataattgttc tatcgatttt ggaggtgatt ttatgtacac
     4261 aaattttaat atcgatttta ataactttaa taaaaaagaa aatgctatta aatttatgtt
     4321 aatgggagta ttactcatta tattaggatt attatgcctt acatttaaga cattaggtat
     4381 aaaattaatt tcttggactt ttggtattgc acttttattc tttgcatatt taaatttaaa
     4441 aaatattaat gagttaaaaa gatatgctac taaagaagaa attaaaccct ctattaatat
     4501 ccaatgggtt ctaataattg catgtatatt actttttgta tttcctcaaa aaatacaaag
     4561 catattttca ttatttttag gattttattt aatctttaat caactagtag cacttgtaaa
     4621 tagtaagaat aatccttatt ctaaatttac aacttggaat atagttaaga ttctatttgg
     4681 tatatgcctt atattatctc cacttttttt atctagattt atagtatcga taatgtcttt
     4741 tttcataata ttatttggac tagttctatt tttctctgga aatacagcga gaaaatatta
     4801 attattttct cgctgtattt ttatattact taaaatagaa tttgtttaag ttatctattt
     4861 gtggtaatat gttttttgta caagctcagc gtacaatttt attagaaata ggtgattttt
     4921 tggataaatt taaatatgct tttgataata aaagatatca tacttggaat tactatctta
     4981 gaaatacttt tggagaaaaa gtttttaagg tatctataaa tgcaggattt acttgcccaa
     5041 acattgatgg aagtcttggt tatggcggat gtacctattg tagcaaagaa ggctcaggtg
     5101 attttgctgg aaaccctaaa gataatctta tcagtcaatt ttataatata aaagaaatga
     5161 tgttaaaaaa atggcctcat gcaaagtata ttggctactt tcaagcctat acaaatacgt
     5221 atgctcctct tgaagtttta aaagaaaaat atgagactat attagaactt gaagatgtca
     5281 taggtctttc aatatccaca agacctgact gtttgccaga tgatgttgta gaatacttat
     5341 ctgaactaaa taaaagaacc aatttatggg ttgaacttgg acttcaaaca attcatgatt
     5401 ctacatctaa aattataaat agaggtcatg attataaaac atttgttgaa ggtgttgaaa
     5461 aactaaagtc taaaaatata aaggttgtcg tacacattat aaatggtctt cctggtgaag
     5521 attataatat gatgatggaa acagcaaagg cagttggtaa aatgggtgta gacggtataa
     5581 aaatccatct attgcatgtt ataaaagata ctcctatgga aaagatgtta caaaatggta
     5641 tgttaactct tatggaacaa gatgaatata tcaatcttgt ctgtgaccaa ttagaaatac
     5701 ttcctgaaac tatgataatc catagactca ctggtgatgg taagagggat gaactagtag
     5761 gtcctatatg gagcctaaaa aaatgggaaa ttttaaatca aattgatgat actttaaagg
     5821 ctagaaattc ttatcagggc tgtaagtttg tttaatacaa aataataact atagaaatgg
     5881 ttatataaat atagtccttt ctatagttat ttagtattta caaaacaaaa tattaatttg
     5941 tacatttata caatatataa taaaaaatag atagtctaaa ctgtatctac ttatatttta
     6001 tttgtactgt ccactttatt ctataaaatt tataaatagt tattttttaa taccaaatat
     6061 aatttggtat aatttttgtt ggactctaaa atgtatacca ataaatcctt tttaagtata
     6121 taattctaaa tactttcagt tttttcaatc tgctttaact tgttggactt ataaaatatt
     6181 cttatttcat cataagaaag attaagtgct actactgcag atattaacat caacatcact
     6241 ccaaataact tccctaagga aaaactttct cctaatatag tgcaaccaat tattactgaa
     6301 ccaactaatt ctactgatgc cacaacacct gcaactgaca actctacacc tttagatata
     6361 cctgctgcat aaaaaatata tgcaagtgca gctggaacaa tgcctaacat tagcatacaa
     6421 gataaaacat ctaaatcctt agcataattt aagatttccc aaggtcttga agaaggaatc
     6481 ataaatatag ctccaaataa gaaactgtat actaatattg ttgaacttga aaattccttt
     6541 aaagcatttt tactaatagt tggcataagt gcatatgcta ttgctgataa taccccaagt
     6601 aaaagtccaa aagcgtttaa accttgaaaa tccaaacgtc caccagtcac tgccataatt
     6661 gcaccaataa aacaaagaat aagtgaaaat aatttgcttc tagtaatatt ttctttataa
     6721 catatttttg aaaatattgc taaaaacagt ggtgatgtat atagtaaaac tgctgcaatt
     6781 gatacacccg caatgtcaat tgctttaaaa taacataaat taaacattgc ctgacatata
     6841 atacctatta ttactgaata tataattcct tttttgctta tctttaagat ttgtggtgtc
     6901 cttatagatg aatatacgcc taaaactata aatccaaaaa acaatcttgt aaatgctact
     6961 tgttctgatg tcagtccatt tcccattaaa aactttccaa ataatccaag tgtagcccat
     7021 aataaccctg ctattgctat aaatacatac cctttacttt tttctcccat tttaaattcc
     7081 cttctatttt tatttagtca atttacactc ttctttttaa gcaaaaacta tgccatctta
     7141 aatcaatata tatcgactct aaaaccctag tctttccaat aatactaata aattttcaat
     7201 ttttttatat ttatttttca cttactttaa gttgatttag acttatttta attgtaaaat
     7261 gagttatata taacttattt aaagttaaaa tagactgaaa cttatatata aatatcaaat
     7321 tttaagtata ttaatcaatt aaacctattt taatatatca ttaaaaattt aggaggaaaa
     7381 tataaaaatg aatttagatt tggaatttta tcaaaaaata ttagaagctt cccatgatga
     7441 aatatgtgtt tctgatgata aaggaataat aatatattgt aataaagcat ttgaagaaaa
     7501 ttatggtcta aaaaaagaag atattttagg aaaaaatgtt tcttttttag aagactctgg
     7561 atattcaaca aaaagcccca taccaattgt attaaaaaca aagactaaat tttcactgga
     7621 acaagatact caaacaggga aaaagcttat cataactgct acccctatat ttgatgaaaa
     7681 tggaaactta gaatttactg ttgaaaattg tagagatata actgaactta ataatataaa
     7741 aaataaactt gaagacacaa aaaagcaagt aaaaaaatat aaatctgaag tagaaacact
     7801 atacagaact gcacttagaa ttgaggatac tgtaattatg gacggaatag ttatgagacc
     7861 aatcataaac acagtaaatc atgtttctaa aacggatgta agtgtacttt tattgggtga
     7921 atctggaaca ggaaaaagct cacttgctag atatatacac cacaacagca atagatctaa
     7981 tggcccattt ataacaataa attgtgcaac tatatctcca caacttcttg aatctgaact
     8041 ttttggatat acttcaggtg cttttacagg tgcaagtact aaaggtaaag ttgggctcgt
     8101 agaattagct aatggaggaa ctcttttttt agatgaaata ggagatatac cacaaaatct
     8161 acaggcaaaa tttttgcaat taatacagga tagaactttt actccagttg ggagcttaaa
     8221 aaataaaaag gtcgatataa gaattatatc tgctacaaat gttgatttag tttcaaaagt
     8281 aaaagaaaaa aagtttagag aagatttata ctatagatta aatgttatag aaataaaatt
     8341 gcctcctctt agagaaagaa gggataatct agtggaaatt ataaaatatt attttaatag
     8401 gtactcaagt gacttcaatc taaataaaac tatttctaaa gaagctatgg atgctattgc
     8461 aaattataga ttcccaggca atataagaga attacaaaat ataattcaaa aaatcttgct
     8521 tacttgtaca gataatcata taacaataga tgacttacca aacattctta caaaaaatat
     8581 acatattacc aataatggaa ataaaacaca tatatcccaa attaataagg ttattatatc
     8641 tgactcaaaa tctactaatt ataaaaataa aaattttgac actttaatta aagagtatga
     8701 aaaaaatata attttggatg cttatgaaaa atttggtagt tcttataaag tagccaaaca
     8761 ccttgaaatc tcacagtcta aagccaatag gttaattaga aagtatacta atacttaatt
     8821 ttaaatttga taaataaaaa cttaacacta tttacatatt gtaaatttgg ccatttactg
     8881 ttattatgaa tatggttgaa attatttaaa taaatactgt tgacttagtt tcatatattt
     8941 accattaaac ttttatcata
//
LOCUS       DAJMZY010000134         8797 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.136, whole genome shotgun sequence.
ACCESSION   DAJMZY010000134 DAJMZY010000000
VERSION     DAJMZY010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8797)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8797)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8797
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.136"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     regulatory      125..229
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            439..2913
                     /gene="gcvPA"
                     /locus_tag="OE968_003364"
     CDS             439..2913
                     /gene="gcvPA"
                     /locus_tag="OE968_003364"
                     /EC_number="1.4.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminomethyl-transferring glycine dehydrogenase
                     subunit GcvPA"
                     /protein_id="HCP7220600.1"
                     /translation="MNELKRVSLYNIHKELGAKLVEFAGWEMPLEYEGINKEHEKVRK
                     SAGIFDVSHMGEVQIKGAESEKFIQNLVTNDISALKINDIIYTPMCYENGGVVDDLLI
                     YKFGEEDYLLVINAGNIDKDVAWIIKQSEGYNVDIKNISSEVSQLAIQGPKAEEILQK
                     ITDIDLNSIKFYKSIPSTKVCGCPCLVSRTGYTGEDGFEIYCKNKYVEIIWNEVLKVG
                     GEDICPAGLGCRDTLRFEAALPLYGHEINEHISPIEGGLSIFVKTNKESFIGKSILSK
                     EKESGAKRKLVGFEMQGKGMPRNGYDIRIGDKTVGFVTTGCASPTTGKILGMGIIDSE
                     YAKVGNEIGIAIRKKVVPAVIVKKPFYKKQYKKDNIILNKENKFSYIPATSEDKSKML
                     KVVGLNSVDELFSDIPEEVKLKRDLNLEIGKSELEVSKIVKRLSEENLSLEDLTCFLG
                     AGAYDHYIPSIIKHITSRSEFYTAYTPYQAEISQGTLQVVFEFQSMIAEITGMEIANA
                     SMYDGATAAIEACIMAMNQTRKSKIVVSKTIHPETLSILRTYLQYKDCEIVEIDFCNE
                     YGTTDIEKLKASVDKDTACVLIQTPNFFGIIEEMEEIEKITHENKAMLIMSVDPISLG
                     VLKTPGEIGADIVVGEAQSLGNPLNFGGPYVGFLASKSKYTRKMPGRIVGQSLDVEGK
                     IAYVLTLQTREQHVRREKATSNICSNQALNALVASIYIATMGKEGFKEVGMQSMKKAH
                     YTYNKLVQTGKYKPIFKGKFFKEFAVQGNLNIETINDKLLEENILGGYNLEYNYPELK
                     NSTLLCVTEKRSKEEIDKLVGIMEGL"
     gene            2913..4370
                     /gene="gcvPB"
                     /locus_tag="OE968_003365"
     CDS             2913..4370
                     /gene="gcvPB"
                     /locus_tag="OE968_003365"
                     /EC_number="1.4.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminomethyl-transferring glycine dehydrogenase
                     subunit GcvPB"
                     /protein_id="HCP7220601.1"
                     /translation="MKEYNSLLIDISKKGRKAYSLPKLDIDDIKIENMIDQDMARQSE
                     LNLPEVGELELVRHYTLLSNKNFGVDTGFYPLGSCTMKYNPKINEDMAALPNFTGMHP
                     YQSSDTAQGSLSLMYDLSRRLAEITGMDEVTLQPSAGSHGEFTGLMIIKAYHENRGDH
                     KRTKVIIPDSAHGTNPASAAMANFDVIQIASDKNGAVDINALKEVLNDEVAALMLTNP
                     STLGLFEKNIKEIATLVHEAGGLLYYDGANMNAIMGITRPGDMGFDVVHLNLHKTFST
                     PHGGGGPGAGPVGVKKELVPFLPIPVIERKEDKYVLNYDREKSIGKIKNFYGNFGVLV
                     RAYTYILTMGRDGLKEASEMAVLNANYIKESIKDDYILPIDTLCKHEFVLGGLPRGEA
                     NIKTIDIAKRLLDYGYHPPTMYFPLIINEALMIEPTESESIETLDSFIEAMKSVAKEA
                     KEEPELLKTAPHNTLVKRVDDARAVKKPILTWSQR"
     gene            4793..7150
                     /locus_tag="OE968_003366"
     CDS             4793..7150
                     /locus_tag="OE968_003366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HCP7220602.1"
                     /translation="MDKVNLERYSCDINVGLNKNQLQSRIDDNLINAFDNGKTKTYKQ
                     IFKDNIFTLFNLINIVLVCLLVSVGSFKNTLFIFIAVINTIIGVIQEIRAKRLLDNLS
                     VIVSNKVSVIREKEKKEIDVQELVLDDIMILKTGNQICADSKVLNGKLEVNESLVTGE
                     SDIIIKNKGDFLYSGSFVVSGEAFVRVENIGKDNYANKIANDAKISKKHNSQLRNSLN
                     AILKIVGIIIIPLGIILFAKQHFGNGDSIATSVVGTVAAVNGMIPEGLTLLTSIALAV
                     GTIKLASHKTLVQELYCVETLARVDTLCLDKTGTITEGKMQVDDIVMLEEVDINEIMG
                     NICNSLKDDNATLNAIRDKYNVLDTYKAKNLIPFSSERKYSGVTFENKGTYLLGAFEF
                     IFKEKNKKLRIEVERYSKKGNRVIVLAHSDSYMEDNNIPEDIKPLAFILILDKIRDEA
                     KETLEFFYNEGVDIKIISGDNPITVSEVARKAGLKTASNFIDATTLKNDSDIYKAVDK
                     YSVFGRVSPQQKKQMILALKKQNHTVAMTGDGVNDVLALKEADCSIAMASGSDVTKNV
                     SNLVLLDSNFASMPKVVMEGRKVINNIQRASSLFLVKTIFSFFLSLLTLFFFSRQYPF
                     VPIQLSLIGAVTVGIPSFFLALEANKSRISGNFLLNILKNALPGALCVTVNVIIVYNI
                     VEYLGYSSSVFSTMCAILTGVCGLLILRQQCLPFNKERLFLIVSMTIAFVIGILFLGG
                     LFSFVALSRELILITMALAILMPIMIKVMLFVLDEILETIVPDLN"
     gene            complement(7236..7553)
                     /locus_tag="OE968_003367"
     CDS             complement(7236..7553)
                     /locus_tag="OE968_003367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine/purine nucleoside phosphorylase"
                     /protein_id="HCP7220603.1"
                     /translation="MSEFKNVTAVKKANVYFDGKVSSRVIILPNGERKTLGLMLPGEY
                     TFSTREEEIMEMLAGSMDVKLPGSNEFVTYKEGQKFNVPSDSSFDLKVNEVVDYCCSY
                     IAD"
     gene            8463..8570
                     /locus_tag="OE968_003368"
     CDS             8463..8570
                     /locus_tag="OE968_003368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013483530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCP7220604.1"
                     /translation="MGRHLWNPSYFVATVSENTEEQIRKYINNQKKQVK"
     gene            8572..>8797
                     /locus_tag="OE968_003369"
     CDS             8572..>8797
                     /locus_tag="OE968_003369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCP7220605.1"
                     /translation="MVVVEKAYKFRMYPNKKQQELINKTFGCCRFVYNKYLAKRIDVY
                     KNNKETFTYKQCSSDLTNLKKELKWLKEPDK"
BASE COUNT         3503 a          958 c         1560 g         2776 t
ORIGIN      
        1 taaaagagaa ataattgata ataaaaactt aacaaaaaaa ttaatacata aaaaaaaata
       61 aatataatgt gttgacattt aattgaaata ttcatacaat aaaattgaaa ataaatattt
      121 ccaaatgaga ttagcgagag agtcctttat acgaaaaggc gccgaagaag aaatttaaga
      181 aatgccaatt tttagagaag ctttcaggca aaaatatcgc taattgatgg gactctggag
      241 agacttaagt taagatacta taagtcaccg aagaagcaaa ataatattaa attattaaat
      301 ctttcaggta tacaaacagg gatatatagg ctaggattat tttccatgct gatatatctt
      361 ttttttatga aaaagtacag gaaataatat caaagttact taaatacagt aggtctaatt
      421 ttctagggag ggttatatat gaatgaattg aaaagagtat ctttgtacaa tatacacaaa
      481 gagcttggag caaaacttgt tgaatttgct ggttgggaaa tgcctttaga atatgagggt
      541 ataaataaag agcatgagaa ggtcagaaaa agtgcaggta tatttgatgt atctcatatg
      601 ggagaggtac agataaaggg agcagagtca gaaaaattta tacaaaacct agttacaaat
      661 gatataagcg cattaaagat aaatgatatt atatatacac ctatgtgtta tgaaaatggt
      721 ggagtagttg atgatttatt aatatataaa tttggtgaag aagattattt attagtaata
      781 aatgcaggta atatagataa agatgtagca tggataataa aacaaagtga aggatacaat
      841 gtagatataa aaaatatatc tagtgaagtg agtcaattag caattcaagg acctaaagca
      901 gaagaaattc ttcaaaaaat cacagatata gacttaaact caataaaatt ttataagtca
      961 attccatcaa caaaagtatg tggttgtcct tgtttagttt caagaacagg atatactggg
     1021 gaagatgggt ttgagatata ctgtaaaaat aaatatgtag aaataatttg gaatgaagtt
     1081 ctaaaggttg gaggagaaga tatatgtcca gctggtctag gttgtaggga tactttgaga
     1141 tttgaagcag ctctacctct atatggacat gaaataaatg aacacatatc tccaattgaa
     1201 ggtggtttat ctatctttgt gaaaacaaat aaagaatcat ttattggcaa atcaatttta
     1261 tcaaaagaaa aagaaagtgg agctaaaaga aagttagtag gatttgaaat gcaaggtaaa
     1321 ggaatgccta gaaatggata tgatataagg attggtgata aaacagttgg atttgtaaca
     1381 acaggatgtg catctccaac gacaggaaaa attttaggta tgggaattat agattctgaa
     1441 tatgcaaaag taggaaatga aataggtata gcaatcagaa aaaaagttgt tcctgctgtg
     1501 atagttaaga aaccttttta taaaaaacaa tataaaaaag ataatattat attaaacaaa
     1561 gaaaataaat tttcatatat acctgctaca agtgaagata aatcaaaaat gttaaaagta
     1621 gttggattaa attcggttga tgaattattt tcagatatac cagaagaagt aaaattaaaa
     1681 agagatttaa atttggaaat tggaaaatct gaattagagg taagcaaaat agtaaaaaga
     1741 ttgtcagaag aaaatttaag tttagaagac ttgacttgtt ttcttggtgc tggtgcatat
     1801 gaccattata taccatcaat tataaaacat ataacttcaa gatctgaatt ttatacagca
     1861 tatactccat atcaagctga aataagtcag ggaactttac aagtagtttt tgaatttcaa
     1921 tctatgattg cagaaattac aggtatggaa attgcaaatg catcaatgta tgatggagca
     1981 actgctgcaa tagaagcatg tataatggca atgaatcaga ctagaaaaag taaaatagta
     2041 gtgtcaaaaa ctattcatcc tgaaactttg tcaatattaa gaacttactt acaatataaa
     2101 gattgtgaga tagtagaaat tgacttttgt aatgaatatg gcactacaga tatagaaaaa
     2161 ttaaaagctt ctgtagacaa agatacagca tgtgttctta tacaaactcc taatttcttt
     2221 ggaattattg aagaaatgga agaaatagaa aagataactc atgaaaataa ggctatgtta
     2281 attatgagtg tagacccaat atcattagga gttttaaaaa caccaggtga gataggtgca
     2341 gatattgttg ttggagaagc tcaatcactt ggaaaccctc ttaattttgg aggtccttat
     2401 gtaggatttt tagctagcaa atctaaatat actagaaaaa tgccaggaag aatagttggg
     2461 caaagtttag atgtagaagg taaaattgca tatgtattaa ctttacaaac tagagaacag
     2521 catgtaagaa gagaaaaagc aacttctaat atatgttcaa atcaagcttt aaatgctctt
     2581 gtagcttcaa tatatatagc tactatgggt aaagaaggat ttaaagaggt tggtatgcag
     2641 tctatgaaaa aagcacatta tacttacaat aagcttgtac aaactggaaa atataagcca
     2701 atatttaaag gtaagttttt caaagaattt gctgtacaag gaaatcttaa tatagaaact
     2761 ataaatgata aactcttaga agaaaatata ttaggtggtt ataatttaga atacaattat
     2821 ccagaattaa aaaattcaac tttgctttgt gtgactgaga aaagaagcaa agaggaaata
     2881 gataagttag ttggaataat ggagggatta taatgaaaga atacaatagt ttgttgatag
     2941 atatatctaa aaaaggtagg aaagcatact cacttccaaa gttagatata gatgatataa
     3001 aaatagaaaa tatgattgac caagatatgg caagacaaag tgagttgaat ttgccagaag
     3061 ttggtgaatt agaattagtt agacattata cattattatc aaataaaaac tttggagttg
     3121 atacaggttt ttatcctttg ggttcttgta ctatgaaata taatcctaaa ataaatgaag
     3181 atatggcagc acttccaaac tttactggaa tgcatccata ccaatcttcg gatacagctc
     3241 aaggttctct ttctttgatg tatgatttat caagaagact tgcagaaatt acaggtatgg
     3301 atgaagttac actacaacct tcagcaggtt ctcatggtga gtttacaggg cttatgatta
     3361 taaaagcata tcatgaaaat agaggtgacc ataagagaac caaagtgata attccagatt
     3421 ctgcacatgg aacaaatcca gcaagtgcag ctatggcaaa ctttgatgtg attcaaatag
     3481 catctgataa aaatggagct gtagacataa atgcattaaa agaggttttg aatgatgaag
     3541 tagcagctct tatgcttact aatccaagta ctcttggttt atttgaaaaa aatataaaag
     3601 aaatagctac tcttgtacat gaagcaggag gacttttgta ctatgatggt gcaaacatga
     3661 acgctattat ggggataaca agacctggag atatggggtt tgatgtggtt catcttaatc
     3721 ttcataagac tttttcaact cctcatggag gtggaggtcc aggagctggt cctgttggag
     3781 ttaaaaaaga attagtacct tttttaccaa taccagtaat tgaaagaaaa gaagataagt
     3841 atgtactaaa ttatgataga gaaaaatcta ttgggaaaat taaaaatttc tatggtaatt
     3901 ttggagttct tgtaagagct tacacatata tactaactat gggaagggat ggacttaaag
     3961 aggctagtga aatggcagtt ttaaatgcta attatataaa ggaaagtata aaagatgatt
     4021 atattttgcc aatagatacc ttgtgtaagc atgagtttgt attaggtgga ttgccaagag
     4081 gagaggccaa tataaaaact atcgatattg caaaaagact actagattat ggataccatc
     4141 ctccaacaat gtactttcct cttattataa atgaggcact tatgatagaa cctacagaaa
     4201 gtgagagtat agagacatta gatagtttta tagaagctat gaaaagtgtt gctaaagagg
     4261 caaaggaaga accagaacta ttgaaaactg ctccacataa tactttggtc aaaagagtag
     4321 atgatgcaag ggcagtaaag aaacctatac taacatggtc acaaagataa atagttaaaa
     4381 agtagagatt taaagtataa agagaattaa atttgtaaga aaaagctatc taacttaatc
     4441 tagtttagat agcttttttg tatattagta tgtatggtat tttctatata aagttttaaa
     4501 ttatattagt gcttatatag aatattgata tgatgattat gtatagatat taataagaat
     4561 tgttgaattt atcttgcctt aactttattt actcttttat attaagaaaa acttaactaa
     4621 aatatagcga aattcataaa aatttaggaa atcttaagaa ttataatatt taaatcttta
     4681 gatttatatt ttattatata aactatagaa taataaaata aaaaaattga gaattttata
     4741 atatatttgt agatttgagt ataaaaaagt gctaagttga aaggagtaaa atatggataa
     4801 ggttaattta gaaaggtata gttgtgatat aaatgttggt ttaaataaaa atcaacttca
     4861 aagtagaata gatgataatt taattaatgc atttgataat ggaaaaacca aaacatataa
     4921 acaaattttt aaagacaata tatttacact ttttaatctc ataaatattg ttttagtctg
     4981 tttattagtt tcagttggtt cttttaaaaa taccttattt atatttattg ctgtaattaa
     5041 tactattata ggagtaatac aagagataag agctaaaaga ttattggaca atctatctgt
     5101 tatagtttca aataaggtat ctgtcataag agaaaaagag aaaaaagaga ttgatgtaca
     5161 agaattagta ttagatgata ttatgatttt aaaaacaggt aatcaaattt gtgcagattc
     5221 aaaagtttta aatggaaaat tagaggtaaa tgagtctttg gttacaggtg aatctgatat
     5281 tattataaaa aataaaggcg attttttata ttctggaagt tttgtagttt ctggagaagc
     5341 ttttgtaaga gttgaaaata taggaaaaga taactatgca aataagatag ctaatgatgc
     5401 aaagatttct aaaaaacata attctcaact tagaaattca ttaaatgcaa tattaaaaat
     5461 tgtaggtata ataataattc ctttaggaat tatattgttt gcaaaacaac attttggaaa
     5521 tggagattct atagctacat ctgtagtagg tacagtggca gctgtaaatg gtatgatacc
     5581 agagggatta acattactta cgagcattgc tctagctgta ggaactataa aacttgctag
     5641 tcataaaact ttagtgcaag aactgtactg tgtagagact cttgctagag ttgatacact
     5701 atgtcttgat aagacaggta caattacaga aggtaaaatg caagttgatg atatagtaat
     5761 gttggaagaa gtggatatta atgaaataat ggggaatata tgtaattctc tcaaagatga
     5821 taatgcaaca ctaaatgcaa taagagataa gtataatgtt ttagatacgt ataaagctaa
     5881 gaatttaata ccattttctt cagaaagaaa atacagtggg gttacctttg aaaataaagg
     5941 tacatattta ttaggtgcat ttgagtttat atttaaggaa aaaaataaaa aacttaggat
     6001 agaagttgaa agatattcta aaaaaggaaa cagagtaata gttttagctc atagtgattc
     6061 ttatatggaa gataataata ttcctgaaga tataaagcca ctagctttta tattgatatt
     6121 ggataaaatt agagatgaag ctaaggaaac tttagaattt ttttacaatg aaggtgtaga
     6181 tataaaaatt atatctggtg acaatcctat aacagtaagt gaggtagcta gaaaagcagg
     6241 tcttaaaaca gctagtaatt ttattgatgc aacaacactt aaaaatgata gtgatatata
     6301 caaagcagtt gataaataca gtgtttttgg aagggtaagc ccacaacaga aaaaacaaat
     6361 gattttagca ttaaaaaaac aaaatcatac agtagctatg actggagatg gtgtaaatga
     6421 tgtactagca cttaaagaag cggattgtag cattgccatg gcatctggaa gtgatgttac
     6481 taagaatgtg tctaatttag tcttattaga ttcaaacttt gcatcaatgc caaaggttgt
     6541 tatggaggga agaaaagtaa ttaataacat tcaaagagca tcttctttgt ttttagtaaa
     6601 gacaattttt tcattcttct tgtcgttatt aacattattc ttcttcagta gacagtatcc
     6661 atttgttcct atacaattat cactcattgg ggctgtaaca gtgggtatac catcattctt
     6721 cttagctctt gaagcaaaca aaagtagaat ttcaggaaat tttttactca atatattaaa
     6781 aaatgcttta ccaggagcac tatgtgtgac agtaaatgta attattgttt acaatatagt
     6841 tgaatattta ggttatagtt caagtgtatt ttccacaatg tgtgctatat taactggtgt
     6901 atgtggtctt ttaatattga gacaacaatg tttgccattt aataaagaaa gattattttt
     6961 aatagtaagt atgactattg catttgttat tgggattcta tttttaggtg gattattctc
     7021 atttgtagca ttgagtagag aattaattct cataactatg gcattagcaa tattaatgcc
     7081 aattatgata aaagttatgt tatttgtctt agatgagata ttagagacaa ttgttccaga
     7141 tttaaattaa ttttaaaatg atataaataa gagcagtttt agttgaactg ctctttttag
     7201 atgtgtttaa ttttatgtaa gaatatgtat ttttattaat cagctatata tgagcaacag
     7261 tagtcaacaa cttcattaac ctttaagtca aaacttgaat cactaggaac attaaatttt
     7321 tgcccttctt tataagttac aaactcattg cttccaggca gttttacatc catacttcca
     7381 gcaagcatct ccattatttc ttcttctcta gtagaaaaag tgtattctcc tggcaacatt
     7441 aatcctaaag tttttctttc tccattaggc agtattatta ctctgctact taccttacca
     7501 tcaaaataaa cgtttgcctt ctttactgca gtaacattct taaattcact cattagataa
     7561 aacctccaaa attatttgta catatatatt atataaaaat aatgtaaaaa atgctatata
     7621 tttacaaaaa aatttagtat ttattaaaaa aattaataag aataaaaaag aggtgaaatt
     7681 gcttaaattg ataaaaaata taaaataaat tgcaaagtaa gcaagaaaag aataagttga
     7741 agagttatat attataaata ttaaaaattt tagtattaat aaaaaagata ttacattaat
     7801 atgaaaatat aggagattag aagtgtttga ttaaaaaata gctacacaca cttgtgactt
     7861 tagtcatgag ttagtagcta aaatagtcag catataggga aacttatatg tagagatagg
     7921 atagaaccta tccaatacta cttgaattgc taaaaacccc taaagctaac caaactaaaa
     7981 cataaggatg aaataaacct aagtgtgaaa gttacgaaag tagaaaaaat tggttagatg
     8041 gtataaggtt aaaccctaag tactttaaaa tgggcaatca gcaggtaagc tccgaatagg
     8101 agaaacttca acgactattc ctcttgaggg aagtacacta caagctattg gtagtggaag
     8161 tgggtagacc ttaacggata atgccgaagg ataagatata gtctgtgctt acgtgaaagt
     8221 gtaagaagtt cataagagaa ctgcataggt agtagcgaac ttatgtgaac gacaacctca
     8281 aaaatgataa aagttaagac ttacggttct tatatatgtt atttaaaaat aaatataaaa
     8341 aaacttcaaa atacttgttt taagtaattg tatattttaa tattatgata ggttatgaaa
     8401 aatggaagtt actcatggta gaggatatgc atatagtatg tcaaatatag acagccagta
     8461 ttatggggag acatctttgg aatcctagtt atttcgttgc tactgtatca gaaaatacag
     8521 aggagcagat aagaaaatat attaataatc agaaaaaaca agtaaagtga ggtggtagtg
     8581 gtggaaaaag cttataagtt tagaatgtat ccaaataaaa aacaacaaga gttaattaac
     8641 aaaacttttg gatgttgtag atttgtatat aataagtatc ttgctaaaag aatagatgtt
     8701 tataaaaaca ataaagaaac ttttacttat aaacagtgta gttctgattt aaccaattta
     8761 aaaaaagaat taaaatggct taaggaacct gacaaat
//
LOCUS       DAJMZY010000135         8712 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.137, whole genome shotgun sequence.
ACCESSION   DAJMZY010000135 DAJMZY010000000
VERSION     DAJMZY010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8712)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8712)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8712
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.137"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            304..1320
                     /gene="gap"
                     /locus_tag="OE968_003370"
     CDS             304..1320
                     /gene="gap"
                     /locus_tag="OE968_003370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011948756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HCP7220606.1"
                     /translation="MKIKVGMNGFGRIGRAVLRIAQEELGDNIEIVAINARATTESLA
                     HLFTYDSCYGTFRGEVEAKDEDTLVVNSKEIKILRYNDPEELPWKELGVDIVIESTGL
                     FTQREKAEKHIKAGAKKVIITAPGKNEDITIVIGVNEKEYDNEKHNIISNASCTTNCL
                     APFAKVLDEKFGIVKGLMTTVHSYTNDQRILDKSHKDLRRARAAAESIIPTTTGAAKA
                     VSRVLPQLEGKLNGFSLRVPTPTVSLVDLVCELKENVTSEQVNSVLKDAAEGELKGVL
                     GYCDKPLVSIDYKGDSRSSIIDALSTMVIEDNMVKVVSWYDNEWGYSSRTVDLVKYVA
                     EKLK"
     gene            1715..2884
                     /locus_tag="OE968_003371"
     CDS             1715..2884
                     /locus_tag="OE968_003371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220607.1"
                     /translation="MEKLTDRRQVKAVSMETFIFLILLVVGFGYVGSIMGAGMMFKVI
                     MSTAHALLLETVFLIMAMAVLAGALSALLSEFGVIALINKIFAVFMKPLYGLPGASIA
                     GAITTYLSDNPAIIPFAKDKTFTQYFKQYQVPALCNLGTAFGMGLILTTFMISQGTEY
                     VLPALIGNLGAIIGSVISVRIMLTFTKKFYKYNPEEDKATGTLEKKDEFREIREGNVF
                     QRALDAILEGGKMGVDMGMAIIPGVLVVCTLVMLLTFGPSTDPVTGQEVYTGAAYEGI
                     KLLPVIGDKLGFILEPLFGFTSPEAIAFPITSLGAVGAAMSLVPEFIKSGAITPNDIA
                     VFTAMGMCWSGYLSTHIGMMDALNARQLAGKAILSHTIGGLCAGAAAHFIFTLVG"
     gene            3264..7517
                     /locus_tag="OE968_003372"
     CDS             3264..7517
                     /locus_tag="OE968_003372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyacyl-CoA dehydratase"
                     /protein_id="HCP7220608.1"
                     /translation="MDELFHIGIDVGSTTVKVVVLNNSNNIVHKEYRRHYSDVKKSVK
                     EVLNGIYEKLGDINTTIIITGSGGIGISKKLGVKFVQEVISSTKSIEYFHPETDVVIE
                     LGGEDAKITYLSGGIDQRMNGICAGGTGAFIDQMASLLKTDASGLNELAKGYNVIYPI
                     ASRCGVFAKTDIQPLINDGANQTDIAMSIFNAVVVQTVSVLSCGRKIEGNVAFLGGPL
                     YFLSELREAFKRVLDLKDENIIFPENAQLYIAIGAGLLSVDEDNIQLKSLIEKLDSIK
                     NIEDGEVNLLEPLFKDKNEYEEFSRRHEKEKINYVDINSIKSNCYLGIDAGSTTTKAA
                     LIDEDGRLVYSYYNSNEGNPLKTTIKVINEVYDILPKNIKILSSTVTGYGEGLIKKAL
                     KIDNGEIETIAHYKAAKFFNKDVDFILDIGGQDMKCLKIKDGVIDNIILNEACSSGCG
                     SFLETFASSLSMTIEEFAHEGIYSQNPVDLGSRCTVFMNSRVKQAQKEGASVGDISAG
                     LSYSVIKNALFKVIKIRDLNEIGNNIVVQGGTFYNDLVLRSFEKLIGKNVIRPNISGI
                     MGAFGSALIAKEKYESGYKTSLLSKEELNNIKLEASVTRCKGCSNHCLLTINKFSDNE
                     IFISGNRCEKGEAIYGDKKIGLEKKKPINLFKYKYNRIFRYKPLEKEEAKNGEIGIPR
                     VLNMYEDYPFWFTFFNAMGFRVVLSDRSSKQLYETGITSIASETVCYPGKLVHGHIEN
                     LIAKGIKNIFYPSVTNENKEDSNADNYYNCPVVISYSEVIKNNVENIRNKNINYINPF
                     ISLNDKEKLKKRLYDELSRHFSDIKITKEEVNHAVDKATDEQNLFKMEIQAAGERALK
                     EIKERNMKGIVLCGRPYHIDPEINHGMPELINSLDMAVLTEDSICHLANVQRPLRVVD
                     QWVYHSRLYKAASFVRDKNYLELVQLNSFGCGLDAVTTDQVQEILNEKSKIYTIIKID
                     EGNNLGAAKIRMRSLKAAMFERESKNIDVKNIKVNRIQYAKNNQITNKHTILAPQMSP
                     IHFQFLEKAVNLSGYNIEILKDTDSSVIEEGLRYVNNDACYPAIIVVGQLITALKSGK
                     YDLNNTSVTITQTGGGCRATNYIGFLRKAIYDAGFKDIPVIALSVNGIEDSGIMDNIS
                     LKLINRLFMSVVYGDLLMKVLYRVRPYEKVTGSANALYEKWVDICKSSLVKAKISVFT
                     RNIKDIVKEFDNLEILDIKKPKVGLVGEILVKFHPIANNNLVDILEREGAEAVVPDLT
                     NFFLSCAFNTIYKHTHLEGSRKSRMIGEAFIYITGIYQRVYKKALDKSERFYAPANIK
                     NVAKSTEPVVSLGNQTGEGWLLTGEMVELLNEGVENIICMQPFGCLPNHIIGKGSIKE
                     LKRLYKNANIIPIDYDPSASEVNQLNRIKLMLSKAFKNI"
     gene            7666..8160
                     /locus_tag="OE968_003373"
     CDS             7666..8160
                     /locus_tag="OE968_003373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HCP7220609.1"
                     /translation="MSLVYDVYKSKLGNLYILSEDGFIVSIYIGDEKFNNLKNECIKK
                     GIDIKRSKEDLKEAISQIDDYFNGKRKVFNLNIRIEGTEFQKSVYREMLKIPYGETLC
                     YSDIARNINNPKSVRAIGQASKSNKIPIIIPCHRVVGKKDIGGYMGNHSDLKEILLNL
                     ERQS"
     gene            8276..8653
                     /locus_tag="OE968_003374"
     CDS             8276..8653
                     /locus_tag="OE968_003374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="monooxygenase"
                     /protein_id="HCP7220610.1"
                     /translation="MCDKVIASKYHEKGFNCAESVIKAYNEEFNTDIPVCLGSGLGSG
                     CGVASLCGAVNASNIIIGYVKGRNHEDESTKAKVYAKDLTTTVRKEYGSELCIDLKKD
                     LVACREIMDFAYDSLKETLKKEL"
BASE COUNT         3526 a          910 c         1596 g         2680 t
ORIGIN      
        1 aaattagagg agattcttga agatatatta tttttaaaaa taagtatagt ttaaaaattc
       61 aaaaaaaaga tggcaaaata tgtcccaagg gacattgagt aaaataaatg atttcagctt
      121 atttacacta aaaagtacat actaaatgag gggtaaaata aagaaaaatg atatactaat
      181 tgtcttttga taataaaaaa acatggaatt tgattattta atcaagaaaa agtattgaac
      241 aaatgattta tttagtgtac aataatcatg taaaaacata gtaatggagg gagacatttc
      301 ataatgaaaa ttaaggtagg aatgaacgga tttggaagaa taggaagagc tgtattaaga
      361 atagctcaag aagaattagg agataatata gaaattgtag ccataaatgc aagagcaaca
      421 acagaatctt tggcacattt atttacatat gattcatgct atggaacttt tagaggtgaa
      481 gtagaggcaa aggatgaaga cactctagta gtaaactcta aagagataaa aatattaaga
      541 tataatgacc cagaagaatt accttggaaa gaattggggg ttgatatagt aatagaatca
      601 acaggattat ttacacaaag agaaaaggca gaaaaacata ttaaagcagg agcaaaaaaa
      661 gtaattataa cagctccagg aaaaaatgaa gatataacta tagttatcgg agttaatgag
      721 aaagaatatg ataatgaaaa gcacaatata atttcaaatg catcttgtac tacaaattgt
      781 ctagctcctt ttgctaaagt attggacgaa aaatttggta tagtaaaagg gttaatgact
      841 acagtacatt catatactaa cgatcaaaga atattagata aaagccataa agatttgaga
      901 agagcaagag cagcggctga atctataata cctaccacta caggagcagc aaaagctgtg
      961 tcaagagtac taccacaatt agaaggaaaa ttaaatggtt tttcacttag agtaccaaca
     1021 ccaacagttt cacttgttga tttagtgtgc gaacttaaag aaaacgttac atctgagcaa
     1081 gttaactctg tgttaaaaga tgctgctgaa ggagaattaa aaggtgtttt aggatattgt
     1141 gacaagccac ttgtttctat agattataaa ggagattcaa gatcatctat tatagacgct
     1201 ctatccacaa tggttataga agacaatatg gttaaggtag tttcttggta tgataatgaa
     1261 tggggatatt cttcaagaac tgttgactta gtaaaatatg tagctgaaaa attaaaataa
     1321 tatatatttc ttaaagcaaa ttttaaaaaa attttttaaa aaaattatat aaaactaaaa
     1381 aaaaagatta tgaaaaatat tgaaggaaaa attttttcat aatctttttt ctttcatgca
     1441 aaaagataca agttacaact tatatttgca tattaggtcg ttagagaagt atatatatat
     1501 ttagtaagga atcatacttt ttataaaatg aaagataaga tgtcgaaaac ttgcataaat
     1561 ctgaaaaatt tttattatta aaatactgat ttccatttta aaaatgataa aaaaatgaca
     1621 aataaagttg caaatagtaa tacttataag tataattaaa aaagagaaaa ggttttgtta
     1681 aactttataa caaaaaaaga agggatgatt caaaatggag aagttaacag acaggagaca
     1741 ggttaaggca gtaagcatgg aaaccttcat tttcctaata ttactagtag ttggttttgg
     1801 gtatgttggt agtattatgg gagcaggaat gatgttcaaa gtaataatga gtacagcaca
     1861 tgctttacta ttggagacag ttttcttaat tatggctatg gcagttcttg caggcgcatt
     1921 aagcgcacta ctttcagagt ttggagtaat agcgttaatt aataaaattt tcgctgtatt
     1981 tatgaagcct ttatatggac tacctggtgc tagtatagca ggagctataa caacttattt
     2041 atcagataat ccagctatta taccttttgc taaagataaa acattcacac agtattttaa
     2101 acaataccaa gttccagcat tatgtaactt aggaacagcc tttggtatgg gacttatctt
     2161 aacaacattt atgatttctc aaggtacaga atatgtactt ccagcattaa ttggtaattt
     2221 aggtgcaatt ataggtagtg tcataagtgt tagaataatg ttgacattta ctaagaagtt
     2281 ttataaatac aatccggaag aagataaagc aacaggaaca ttagagaaaa aggatgaatt
     2341 tagagaaatc agagaaggaa atgtatttca aagagcttta gatgcaattc ttgaaggtgg
     2401 taaaatgggg gtagatatgg gaatggctat aattcctgga gtcctagtag tatgtacatt
     2461 ggtgatgtta ttaacttttg gaccatctac agatcctgtt acaggtcaag aagtttatac
     2521 aggagctgca tatgaaggaa taaaattact tccagttatt ggagataaac ttggatttat
     2581 attagaacca ttatttggat ttacatcacc agaggcaata gcattcccta taacttcatt
     2641 gggagctgtt ggcgcagcaa tgtctctagt tccagagttt ataaagtcag gagctataac
     2701 tcctaatgat atagcagtat ttacagctat gggtatgtgt tggagtggat atttaagtac
     2761 acatattggt atgatggatg cattaaatgc tagacagttg gcaggtaaag ctattctttc
     2821 tcatacaata ggtggtttat gtgcaggagc agctgctcac tttatattta cactcgtagg
     2881 ataaatgtaa tcagctaaga taaaaaataa tatacaaaaa atggttgttg atatgtaata
     2941 agaatttaca tatcaacaac catttttttc tgactaaaga taatttataa tacataaaca
     3001 ttaagtggat attagagtta agttatattt atgtaaaaag taacaaaaat ctgtagaaat
     3061 ttatgacaaa atttagtaca ctaactatat gttcttattt aaaatttaag gttagaatta
     3121 ggaattacct agtagagtaa gctttgatta ataaaagaat cataaaataa aaatattagt
     3181 cataaagatt ataaataact tacttaaaat aaagccatag aacttacaaa aattaaaaaa
     3241 gcatataaat atggaggggt acaatggatg aattatttca tataggaatt gatgtaggtt
     3301 ctacaacggt gaaggttgtg gtacttaata atagtaataa tatagttcat aaagaatata
     3361 gaagacatta ttctgatgta aaaaaatcag ttaaagaagt actaaatggt atatatgaaa
     3421 aattgggaga tataaatact accattataa taactggttc aggtggaatt ggaatatcaa
     3481 aaaaattagg tgtaaaattt gttcaggaag ttatatctag tacaaaatca atagagtatt
     3541 ttcatcctga aactgatgtt gtcatagaac ttgggggtga agatgcaaag ataacatatc
     3601 taagtggagg aatagaccaa agaatgaatg gaatatgtgc aggtggcact ggagcattca
     3661 tagaccagat ggcatcactt ttaaagacag atgccagtgg attaaatgaa cttgctaaag
     3721 ggtataatgt tatatatccc atagcttcaa gatgtggtgt ttttgctaaa acagatattc
     3781 aacctcttat aaatgatgga gccaatcaga ctgatatagc aatgagtatt ttcaatgcag
     3841 ttgtcgtaca aactgtgagt gtcctttctt gtggaagaaa aatagaagga aatgttgcgt
     3901 ttttgggtgg tccattgtac tttttatctg aacttagaga agcatttaaa agagtattag
     3961 atttaaaaga tgaaaacata atcttcccag aaaatgcaca actttatatt gctattggag
     4021 caggattatt atcagtagat gaagataata tacaactaaa atctctaata gaaaaattgg
     4081 atagtataaa gaatattgaa gatggagaag taaatttatt agaaccttta tttaaagata
     4141 aaaatgagta tgaagaattt tcaagaagac atgaaaaaga aaaaataaat tatgtggaca
     4201 taaattcaat aaaaagcaat tgttatttag gaattgatgc aggctcaact acaactaaag
     4261 cagcacttat tgatgaggat ggaagacttg tatattctta ttataatagc aatgaaggaa
     4321 atccattaaa aacaaccatt aaagttataa atgaagtata tgatatatta ccaaaaaata
     4381 ttaaaatatt gagttcaact gtaactggat atggagaagg tcttattaaa aaagctctta
     4441 aaatcgataa tggagagata gagactatag cacattacaa agctgctaaa tttttcaaca
     4501 aagatgtaga ttttatactt gatattggtg gtcaagatat gaagtgccta aaaataaaag
     4561 atggagtaat tgataatata atattaaatg aggcttgttc atcaggttgt ggctcatttt
     4621 tagagacatt tgcaagttct ttatctatga caatagaaga atttgcgcat gaaggtattt
     4681 attctcaaaa tcctgtagat ttaggttcaa gatgtactgt atttatgaat tctagagtaa
     4741 aacaagctca aaaagaaggt gcaagtgttg gagatatatc agcagggcta tcttattcag
     4801 taataaaaaa tgctttattt aaagtaataa agattagaga tttaaatgag attggtaata
     4861 atattgttgt acaaggtgga accttttata atgatttggt gcttagaagc tttgaaaaac
     4921 taattggaaa aaatgtaatt agacctaata tttcaggaat tatgggagct tttggttcag
     4981 cacttatagc taaagaaaaa tatgaaagtg gatacaaaac atccttgtta tctaaggaag
     5041 agttgaataa tatcaagcta gaagcaagtg taactagatg taaaggttgt tcaaatcatt
     5101 gtcttcttac aataaataaa ttttctgata atgaaatttt tatttcaggt aatagatgtg
     5161 agaaaggtga agctatttat ggtgataaaa aaataggatt agaaaagaaa aaaccaataa
     5221 atttatttaa gtacaaatac aatagaattt ttagatacaa accattggaa aaagaagaag
     5281 caaaaaatgg ggaaataggg ataccaagag tattaaatat gtatgaagat tatccatttt
     5341 ggtttacttt tttcaatgct atgggcttta gagttgtact ttcagatagg tcatcaaaac
     5401 agttatatga aactggtata actagtattg catctgaaac agtttgttat ccaggaaaat
     5461 tagttcatgg acatatagaa aatttaattg caaaaggtat aaaaaatata ttttatccaa
     5521 gtgtaacaaa tgaaaataaa gaggattcaa atgcagataa ttattataat tgtcctgttg
     5581 taatatcata ttctgaagta ataaaaaaca atgtagagaa tataagaaat aagaacataa
     5641 attatataaa tccatttata agtctaaatg acaaggaaaa attgaagaaa agactctatg
     5701 atgaattatc aagacatttt tctgatataa aaataactaa agaagaagtt aatcatgcag
     5761 ttgataaagc tactgatgaa cagaatttat ttaaaatgga gatacaagca gcaggtgaaa
     5821 gagcacttaa agaaataaaa gaaagaaata tgaaggggat tgtgttatgt ggaagaccat
     5881 atcatataga cccagaaata aatcatggaa tgccagagct tataaattca ttagatatgg
     5941 cagtgcttac tgaagactct atatgtcatt tagccaatgt acaaagacca cttagagttg
     6001 tagaccaatg ggtatatcat tcaagattgt ataaagcagc tagttttgta agagataaaa
     6061 actatttgga acttgttcaa cttaattcat ttggctgtgg attagatgca gtaactacag
     6121 accaggttca agaaatactt aatgaaaaat cgaagatata tactattata aagattgacg
     6181 aaggcaacaa tttaggagca gctaagataa ggatgaggtc cttaaaagca gctatgtttg
     6241 agagagaaag caaaaatata gatgtaaaaa atataaaggt aaacaggata cagtatgcta
     6301 aaaataatca gataacgaac aaacatacta tattagcacc acaaatgtct ccaatacatt
     6361 tccaattcct tgaaaaagct gttaacttaa gtggttataa tatagaaatt ctaaaagata
     6421 ctgatagtag tgtaattgaa gaagggttaa gatatgtaaa taatgatgca tgttatccag
     6481 ctataatagt tgtaggtcag ctaataacag cattaaaatc tggcaaatat gatttaaata
     6541 acacttctgt tactataact cagactggtg gaggttgtag agctacaaat tatattggat
     6601 tcttaagaaa ggctatatac gatgctggat ttaaagatat tcctgtcatt gcacttagtg
     6661 taaatggaat agaagatagt ggtataatgg ataatatatc actaaaatta atcaatagac
     6721 tctttatgtc tgttgtttat ggtgatttgc tgatgaaagt actatataga gtaagaccat
     6781 atgaaaaagt tactggaagt gcaaatgctc tatatgaaaa atgggttgat atatgcaaat
     6841 cttctcttgt taaagcaaaa atttctgtat ttactagaaa tataaaagat atagtaaaag
     6901 aatttgataa tttagagata ctagatatca aaaaaccaaa agtaggtttg gttggagaaa
     6961 tattggtgaa attccatcca attgcaaata ataatttagt agatatatta gagcgagaag
     7021 gtgctgaagc agtcgtgcca gaccttacaa atttcttctt aagttgtgcc tttaatacta
     7081 tatacaaaca cactcattta gaaggaagta gaaagagtag aatgatagga gaagcattta
     7141 tatacataac tggaatatat caaagagtat ataaaaaagc acttgataag agtgagagat
     7201 tttatgctcc agccaatata aaaaatgttg ctaaaagtac agaaccagta gtgtcattag
     7261 gtaatcaaac tggagaaggt tggcttttaa caggtgagat ggttgaatta ttaaatgaag
     7321 gtgtagaaaa cattatttgt atgcaacctt ttggatgttt acctaatcac ataattggta
     7381 agggttctat aaaagaatta aagaggttgt ataaaaatgc aaatataata cctattgatt
     7441 atgacccttc tgcaagtgag gtaaatcaac ttaacaggat aaaacttatg ctttctaagg
     7501 cttttaaaaa tatataagat ttatattttg atatgttaaa agttaatgaa tttaaaaata
     7561 tactctatat taagtatcta taaaaaagag ttatcctatt ttttagggta actctttatt
     7621 agttaaaaaa ttatatgtat actgatatta aaggggggaa gtaatatgag tttagtatat
     7681 gatgtttata aatcaaaatt aggaaatttg tacatattaa gtgaagatgg ttttatagtt
     7741 agtatataca taggagatga aaaatttaat aatttaaaaa atgaatgtat taaaaaagga
     7801 attgatataa agagaagtaa ggaagattta aaggaagcaa taagccagat agatgattac
     7861 tttaatggaa aaagaaaagt ctttaattta aatattcgta ttgaagggac tgaatttcaa
     7921 aaatcagttt atagggaaat gttaaaaata ccttatggag aaacattgtg ttattcagat
     7981 atagcaagaa atataaacaa tccaaaatca gtaagagcaa taggacaagc aagtaaaagt
     8041 aataaaattc caataataat accttgtcat agagtagttg gcaaaaaaga tattggtgga
     8101 tatatgggga atcattctga tttgaaagag atactattaa atttagaaag acagagttaa
     8161 cttagaaaga aatgttttta ttgttaatat ttgatataat aatagtaaaa agaagtattt
     8221 tttacaaaaa caatgaagaa tttattttaa tttataaaaa tgagggggaa ttttaatgtg
     8281 tgataaagtt atagcatcaa aatatcatga gaagggattt aattgtgcag aatcagttat
     8341 aaaagcatat aatgaggaat ttaatacaga tataccagtt tgtttaggaa gtggactggg
     8401 ttcagggtgt ggggttgcta gtttatgtgg tgcagtaaat gcatcaaata taataattgg
     8461 atatgtaaaa ggcagaaacc acgaagatga aagtactaaa gctaaagtat atgctaaaga
     8521 tttaactaca acagtaagaa aagagtatgg ttcagagtta tgtatagacc taaaaaaaga
     8581 tttagttgct tgtagagaaa taatggattt cgcatatgat agtctaaagg aaactttaaa
     8641 aaaagaatta taagaaaata agctatcaag tataaattat ttgatagctt atttttatag
     8701 tcgatactaa at
//
LOCUS       DAJMZY010000136         8666 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.138, whole genome shotgun sequence.
ACCESSION   DAJMZY010000136 DAJMZY010000000
VERSION     DAJMZY010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8666)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8666)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8666
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.138"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            138..1061
                     /locus_tag="OE968_003375"
     CDS             138..1061
                     /locus_tag="OE968_003375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2520 domain-containing protein"
                     /protein_id="HCP7220611.1"
                     /translation="MGSGKVGTSLANYFLSKGYCVSGFYGRNQLSLLESTNLTKTKIY
                     SNLKDIIYENDILFITTSDDSIEIIDKKLSKFNLKHKYICHTSGSLKSSILFCSKKAG
                     ALIYSIHPIFAFSNKNTNIKKMKDICFSIEGDNEQDDLVIQNFIDDLGNQFFIRDKDT
                     SSTYHLANVLVSNLVLSLLDIGVSYFIKLGLSEEESLKAISPLVKKNIENILDNGFTK
                     ALTGPVSRGDITPIRKHLSVLDKKDEDIYKILSLNLLKIIALGNDNSLKGIKNITIEN
                     AIENLISKSEKYKEIYKLLGGKNDEKYHTDF"
     gene            1036..1863
                     /gene="panB"
                     /locus_tag="OE968_003376"
     CDS             1036..1863
                     /gene="panB"
                     /locus_tag="OE968_003376"
                     /EC_number="2.1.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011721175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate
                     hydroxymethyltransferase"
                     /protein_id="HCP7220612.1"
                     /translation="MKNTIQTFKNAKYEGKKLSMLTAYDYSIAKIMDECDINGILIGD
                     SLGMVIKGEENTLSVTIDEIIYHTKAVKNGVKNALIVSDMPFLSYHVSIEDAVKNAGR
                     LIKEGGAHAVKLEGGSNVIKQIESIVNAQIPVMGHLGLTPQSVNSFGGFKVQGNTSET
                     ARQLIEDAKLIEKAGAFSIVLEGVPTKIAEMVTNSISIPTIGIGAGINCDGQILVYQD
                     MLGMFGDFVPKFVKQYANIGDIMKDSIKNYILEVNTGTFPQEKHSFSINESELEKLY"
     gene            1882..2730
                     /locus_tag="OE968_003377"
     CDS             1882..2730
                     /locus_tag="OE968_003377"
                     /EC_number="6.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantoate--beta-alanine ligase"
                     /protein_id="HCP7220613.1"
                     /translation="MLVKEIKLLRNIIKDWRKHGYSIGLVTTMGFLHEGHQSLIKKAV
                     KENDKVVVSVFVNPTQFGPNEDFNSYPRDIDKDFKYCMDSGATVVFNPSPEEMYLKGN
                     CTTINVSGLTDFLCGAKRPVHFGGVCLVVSKFLNIVTPDKAYFGEKDAQQLAVIKRMV
                     KDLNIDTEIIGCPIIRENDGLAKSSRNTYLSEEERKSALILNKSLSLAKEELVKGNLN
                     PENIKELITAKINSEHLAKIDYVEIVDSETLQPVKQIEHSILVAIAVFIGKTRLIDNF
                     TFELNI"
     gene            3141..3323
                     /locus_tag="OE968_003378"
     CDS             3141..3323
                     /locus_tag="OE968_003378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220614.1"
                     /translation="MFKDKIDECVHIMTAYIASLKEYYSFIETQIGDFIKKYGEDVVE
                     LCLHRVMILLCECGLA"
     gene            4155..5069
                     /locus_tag="OE968_003379"
     CDS             4155..5069
                     /locus_tag="OE968_003379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2935 domain-containing protein"
                     /protein_id="HCP7220615.1"
                     /translation="MIDNQKYVILSLELHLFFSRIMKEHALFLEAGFTNKNYNLAMEA
                     DHYKKQFEDLLSYTVSASNGIIRPDILYSEELVTTLTSVAEQKTEEFTGIEINKNITT
                     RELNLQSGVNPQVGQDLVNYVAQLNSDAIRLLDGLINFKERVLDGVLSCTIFTSNYPL
                     LLEHIIHEANLYRYYVVDLENKIDIESKNAKEIELFWDHIMMEHALFMRGLLDPSEGE
                     LINTSNDFAIKFNELIEKTNEMTDSNIKNITEETLNETVEFKDFKEAGASGIEQCKIK
                     SIILPLLADHVLREANHYIRILESYKNM"
     gene            5459..6106
                     /locus_tag="OE968_003380"
     CDS             5459..6106
                     /locus_tag="OE968_003380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate utilization protein"
                     /protein_id="HCP7220616.1"
                     /translation="MIRQTPLEKRYDKLGPHIVTALKKRYFDAYYCKTRNEALQQILD
                     LIPQNHVVSWGGSETLKEMGVQTAVREKGFKVIDRDLAKTPEERTEIMRQALLCDTFL
                     MSSNAISEDGQLFNIDGNGNRVAAMIFGPKNVIVVAGMNKIVKNIDDAIQRTRTIASP
                     AVVQRFQDVNTPCYINGSCIDCTSPESICAYMVTTRISRPAKKIKVILVGENLGL"
     gene            complement(6273..6842)
                     /locus_tag="OE968_003381"
     CDS             complement(6273..6842)
                     /locus_tag="OE968_003381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HCP7220617.1"
                     /translation="MKKFIICIIMFAISVLVLAGCTNDNKIKNEVDSMFNSIKTQDAD
                     TVDKYFPKSGLGNLIYEDKEGFKMYSKNMTWEISDIKNNKDKVTVDLKINNTDMVSIL
                     KKNPPKLGEMMPNPTMKDIDSAKKKEFNITLELVKSGDNYVCKVNQESAMKLLNVITG
                     GGIDYLADYNKDYYKQLDEEQKNYENKNS"
     gene            complement(6847..7746)
                     /locus_tag="OE968_003382"
     CDS             complement(6847..7746)
                     /locus_tag="OE968_003382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HCP7220618.1"
                     /translation="MKLLSKVNNNIRLITQVAFTALTNGYVNGFLEGTIYGGESKKLC
                     VPGLNCYSCPGALGACPIGSLQAVLSSREYKFSFYVVGFLMAFGAFFGRFVCGWLCPF
                     GLVQDLLHKVPFPVKIKKVYGDKYLKYLKYIVLIMFVIILPVAIVNVAGGGNPWFCKW
                     ICPSGTLLGGILLILGNENLRESIGFLFSWKLSILLLILLMSIITYRPFCKYICPLGA
                     IYGFFNPISIYRFKIDKDKCTNCTACQTKCKLDIPIYKDVNSPDCIRCGECIKVCPQN
                     AITTTFSKDKKENNICAKKYRGI"
     gene            complement(7757..7906)
                     /locus_tag="OE968_003383"
     CDS             complement(7757..7906)
                     /locus_tag="OE968_003383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220619.1"
                     /translation="MSNFIKDNKKGISIIAISIIFIALGTYRGETNTVLTKAIMICLE
                     CIGIG"
     gene            complement(7899..8483)
                     /locus_tag="OE968_003384"
     CDS             complement(7899..8483)
                     /locus_tag="OE968_003384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HCP7220620.1"
                     /translation="MKRFFIVVLGCICVLGMISGCSKKESKPVEKNKNNSEWFSNLDT
                     EDVDGNKVTKEIFSNKELTLINVWTTWCGPCVGEMPELEALSKEYESNNSNVAIKGLV
                     VEVDKTDMRTGLSNEEKNLVKDIMKKSDATYQQLTVSEELKKTDFKRVMEFPTTYFVD
                     KKGNFVGEKVVGANSKEDWKKIIDERLKMVKANE"
BASE COUNT         3289 a         1208 c         1125 g         3044 t
ORIGIN      
        1 gatggtatct tgttataaga actatacttt aaatgttttt aattattttg tcttatgtaa
       61 ctcatatcct caggaatgag attagaaatt aagatgttgt atcacaaagt ggaggtgata
      121 ctattaaaat aggctttatt ggttctggaa aagttggaac atctttggca aattattttt
      181 tatcaaaagg ttattgtgtt tcaggctttt atggaaggaa tcaattatct ttattagaat
      241 caacaaattt aacaaaaaca aagatttaca gcaatttgaa agatataatt tatgaaaacg
      301 atatattatt tattacaaca tcagatgatt ctattgaaat tatagacaaa aaactttcca
      361 aatttaattt aaaacataaa tacatttgcc acacaagtgg ctctttaaaa tctagtatat
      421 tgttctgttc aaaaaaagca ggtgcattaa tttattctat ccatcctata tttgcatttt
      481 ccaataaaaa taccaacata aaaaaaatga aagacatttg tttttccata gaaggtgata
      541 atgaacaaga tgatttagtt attcaaaatt tcatagatga tttgggaaac caatttttta
      601 taagagataa ggatacttca tccacttatc atttagctaa tgttttagtt tcaaatttag
      661 tattatcttt actagatata ggagtaagtt actttattaa attaggttta tctgaagagg
      721 aatctttaaa agctatcagt cctttagtaa aaaaaaatat agaaaatata cttgataatg
      781 gctttactaa agctcttact ggtcctgttt ctcgtggaga tataacacca ataagaaaac
      841 atctatctgt attggataaa aaagatgagg atatttacaa aatactatcc ttaaacctac
      901 taaaaataat tgccttagga aatgacaatt cattaaaagg tataaaaaat attactatag
      961 aaaatgcaat cgaaaattta ataagtaaat ctgaaaaata caaagaaatt tacaaacttt
     1021 taggaggaaa aaacgatgaa aaataccata cagactttta agaatgctaa atatgaagga
     1081 aaaaaactat ctatgcttac tgcttatgac tactcaattg caaaaataat ggatgagtgt
     1141 gatataaatg gtattttaat aggagattca ttaggaatgg ttataaaagg tgaagaaaac
     1201 actctatctg ttaccataga tgaaattata tatcatacaa aagctgtaaa aaatggtgta
     1261 aaaaatgcct taatcgtaag tgatatgcct tttctatctt accatgtttc tatagaagat
     1321 gcagttaaaa acgcgggtag acttataaaa gaaggaggag ctcatgctgt aaagttagaa
     1381 ggtggctcaa acgttataaa gcaaatagaa agcattgtaa atgctcaaat acctgtaatg
     1441 gggcatttag gattaactcc tcaatcagta aattcatttg gtgggtttaa ggttcaagga
     1501 aataccagtg aaacagcaag acaacttatt gaagatgcta aattaataga aaaagcaggt
     1561 gcattctcta ttgtccttga aggagtgcct acgaaaatag ctgagatggt aactaattct
     1621 atttcaattc ctacaatagg tataggggca ggaattaact gtgatggaca aattttagtt
     1681 tatcaagata tgttgggaat gtttggagat tttgttccta agtttgtaaa gcagtatgca
     1741 aatataggag atataatgaa agattcaatt aaaaattaca tcctagaagt taatacaggt
     1801 acatttccac aagaaaaaca cagcttttca ataaatgaat ctgagttaga aaaattatac
     1861 taatattaag gatggtacaa aatgcttgta aaagaaatta aattactaag aaatataatc
     1921 aaagattgga gaaaacatgg ctattctata gggcttgtta caacaatggg atttttacat
     1981 gaaggacacc aaagtcttat aaaaaaagct gtaaaagaaa atgataaagt agtagtgagt
     2041 gtatttgtaa atccaactca atttggacca aatgaagatt ttaatagcta tccaagagat
     2101 atagataaag attttaaata ttgtatggat agtggagcaa cagtagtctt taacccatca
     2161 ccagaagaaa tgtatttaaa aggtaattgt actaccatta atgtttctgg acttacagat
     2221 tttctttgtg gagctaaaag acctgttcat tttggaggtg tctgcctagt tgtttcaaag
     2281 tttctaaata tagtaacacc tgataaagct tattttggag agaaggatgc ccaacaatta
     2341 gctgtaatta aaagaatggt caaggattta aacatagata cagaaataat aggctgtcct
     2401 ataattcgtg aaaatgatgg attagcaaaa agttcgagaa atacatatct ctctgaggaa
     2461 gaacgaaaat ctgctctaat attaaataag agcttaagtt tagcaaaaga agaattagta
     2521 aaaggcaatc taaatccaga gaatataaaa gaattaataa cagctaaaat aaattctgaa
     2581 cacttagcaa aaatagacta tgttgaaatt gtagatagtg agacattaca acctgttaag
     2641 caaatagaac attctatact tgtggcaatt gctgtgttta taggaaaaac cagactaatt
     2701 gataatttta catttgagtt aaatatatag tctataattt tatataatat atctaaaaaa
     2761 taatagaata cctaaaaagt aataaattac ctaaaaaata ataaattgct tagaaaataa
     2821 tagattacaa taactaaaat tttaaaatta aattccttaa aagtatgatt aattataatt
     2881 atataagtat attcttatta cacttatatt aatttatatt aaatatctac taactcaaat
     2941 attcataatt aaactttaaa ctggataaat tttcttttaa gaatgaaagt ttatccagtt
     3001 ttgcgattat aataaccagt tttacatatc cacttgtaaa atatatctaa gcaatatatc
     3061 atactatata gatttatgag tgaaataata tctgctattt actgaatatt tttatttttc
     3121 gttttttagg gggattagtt gtgtttaaag ataagattga tgaatgtgtt catataatga
     3181 ctgcatatat tgctagttta aaagaatact attcattcat agaaactcaa attggtgatt
     3241 ttattaaaaa atatggagaa gatgttgtag agttatgtct ccatagagtg atgattctac
     3301 tatgcgaatg tggtttggca taaaattaaa tttattaaaa tgggtaagaa gaatcctata
     3361 taatattctt cttacccatt ttaatatatc aatttcatag cttatcgttt aaaatatttt
     3421 acatccatta ctagacaact ttacattctc tttttaattc tagtatattt aaatcatttt
     3481 agttgctcct tatttattct tattacttgt tttattttat aaataaaata attcttttta
     3541 ataatgtttt ttgttgatat tcctatcaca catccaatta tttatcattg tcttgaaatt
     3601 gtttgcatac ttaatttaat ccaattgaaa caccccagca tagaatcccc tgtaaaatag
     3661 aagttggatt aaatcctaac atctatacag aaaatactac tccaagcaca agcaatataa
     3721 tggaatatat ttatcactta attttttata ctttttaaat cccataccta aagcattaag
     3781 tgcagctatt agaattaata attgttgtgg tataaaatta tgcttgcttc atatttattc
     3841 attttttact ataaaagttc ttgttttaca aaaaacattt gttttgtatc aaaataatac
     3901 ttgtaaatta cataattctc ataaaaattt ctagtattac ttgtactctt aataaataat
     3961 agccaacaag taccttaaat cattatatct atatctaata agaaacacag taagataatt
     4021 ttttcgccca taacttaata aaaactgttg atattagtag caattgaatt tagttaattt
     4081 atttataata tacataaatt taaatattac gaataaagta ttataaatag gatactttct
     4141 aaagggagga aattatgata gataatcaaa aatatgttat tttatcacta gaattacatt
     4201 tatttttttc aagaattatg aaagagcatg ctcttttttt agaagcagga ttcacaaata
     4261 aaaattataa tcttgctatg gaagctgacc actataaaaa gcaatttgaa gatttattat
     4321 catacactgt tagtgctagt aatggtataa ttagacctga tatattatat tcagaagagc
     4381 ttgtaactac tctcacatca gttgcagaac aaaaaacaga agagtttaca gggatagaaa
     4441 taaacaaaaa catcactaca agagaattaa atctacaaag tggtgtaaac ccacaagttg
     4501 gtcaagactt agtgaactat gtagctcaac ttaactctga tgcaataaga ttacttgatg
     4561 ggcttattaa ttttaaagaa agagtcttag atggtgtact atcatgtact atatttacat
     4621 caaactaccc tctacttctt gaacatataa tacatgaagc aaatttatat cgttattatg
     4681 tagttgacct tgaaaataaa atagatattg agtcaaaaaa cgctaaagaa atagaattat
     4741 tctgggacca tattatgatg gaacatgctc tgtttatgag aggattacta gacccctcag
     4801 aaggtgaact aataaatact tcaaatgatt ttgctataaa atttaatgaa ttaattgaaa
     4861 aaacaaacga aatgactgat tctaatatca agaacattac agaagaaact ctaaatgaaa
     4921 ctgttgagtt taaagatttt aaagaagcag gagcatcagg aatagaacag tgtaagataa
     4981 aatctataat attaccactt ttagcagacc atgttttaag agaggcaaat cattatatta
     5041 gaatattgga gagttataaa aacatgtaat taaaaattac ttttaaaata atctttgcat
     5101 atttagataa aataaaggta cagttaactg tacctttatt ttttataaac ttataaaatt
     5161 taaacaagtt attcataaaa taaaataata atcatctata acccacaact ttattttata
     5221 ttaaataaaa agtattagtg attatgtttt ataggtattt ctttattcag ttatttatta
     5281 aaaactaata gtaaatctta tactaatcgc atatttatgt tataactata ttgtaactat
     5341 tttcgtaatc ttaggaaaag attacttata aaattaacct tatacaataa tatatcgtat
     5401 aatcttaatt agcataatag ttacaatatt aaaatttaaa tatgggagtg attttagtat
     5461 gataagacaa acaccattag agaaacgata tgacaagcta ggtcctcata ttgtaacagc
     5521 actcaaaaaa cgttattttg atgcttatta ctgtaaaact agaaatgaag ctttgcaaca
     5581 aattttagat ttaattcctc aaaatcatgt agtatcatgg ggaggatctg aaacacttaa
     5641 agaaatgggc gtacaaactg ctgttagaga gaaaggattt aaagttattg atagagattt
     5701 agcaaaaact ccagaagaaa gaactgaaat tatgcgtcaa gcacttctat gcgatacttt
     5761 tttgatgagt agcaatgcaa ttagtgaaga tggacaactc tttaatattg atggaaatgg
     5821 caatcgtgta gctgcaatga tatttggtcc aaaaaatgtt atagttgtag ctggtatgaa
     5881 taaaattgta aaaaacattg atgatgcaat acaaagaact agaacaattg catctccagc
     5941 agttgttcag cgttttcaag atgtcaatac accatgctat attaatggaa gttgtataga
     6001 ttgcacaagc cctgaaagca tttgtgcata catggttact acaagaatca gtcgtccagc
     6061 aaaaaaaata aaggtaatat tggtaggaga aaatcttggt ctataaaata tacatacatg
     6121 taaatagctc tataaataat aaaatcatat gaaataactt atttctaaaa gtggtagaat
     6181 aaaagcttct acaagacttt cattctacca cttttatatt cttttaattt gtgtttctat
     6241 attattaatt gctccgattt tcatatatat tactaactat ttttattttc ataatttttt
     6301 tgttcttcat caagctgttt ataataatct ttattatagt cagctagata atctatacca
     6361 cctcctgtaa tcacatttaa taatttcatt gcagattctt gattaacttt acaaacataa
     6421 ttatcaccag atttaacaag ctctaatgta atattaaatt cttttttctt tgcagaatca
     6481 atatctttca tagttggatt tggcatcatt tctcctagtt taggaggatt cttttttaaa
     6541 atagaaacca tatcagtatt gttaattttt aaatctacag tcactttatc cttattattc
     6601 tttatatctg aaatttccca agtcatattt ttagaataca ttttaaatcc ttctttatct
     6661 tcgtatataa gattacctaa ccctgatttt gggaaatact tatcaacagt atctgcatct
     6721 tgtgttttta ttgaattaaa catactatcc acttcatttt ttatcttatt atcattagta
     6781 caaccagcta acaccagtac tgatattgca aacattataa tacatataat aaatttcttc
     6841 attaaattat atccccctat acttttttgc acaaatatta ttctcttttt tatcttttga
     6901 aaaagttgta gtaattgcat tttgtggaca aacttttata cattcaccac acctaataca
     6961 gtctggacta tttacatctt tatatattgg tatatcaagc ttacattttg tttgacatgc
     7021 tgtacaattt gtacatttat ctttatcaat tttaaatcta tatattgaaa taggattaaa
     7081 aaaaccatag attgctccta aagggcatat atacttgcaa aatggcctat aagtaatgat
     7141 tgacatcaat aatatcaata gcaaaatact taacttccag ctaaataaaa atcctattga
     7201 ttctcttaaa ttctcatttc ctaaaataag tagtattcct cccaaaagtg ttcctgaagg
     7261 gcaaatccat ttacaaaacc aaggatttcc accccctgct acatttacaa tagcaactgg
     7321 caaaataatt acaaacatta ttaagactat atactttaga tattttagat atttatcacc
     7381 ataaactttt tttatcttta ctggaaaggg tactttatgt agtaaatctt gtacaagtcc
     7441 aaagggacaa agccaaccac aaacaaatct gccaaaaaaa gcaccaaatg ccattaaaaa
     7501 accaacaaca taaaatgaga atttatactc tctgcttgat aaaactgctt gtaatgaacc
     7561 tattggacat gctccaagtg cacctggaca tgaataacaa ttcaatccag gtacacataa
     7621 ttttttactt tctcctccat atatagttcc ttctaaaaat ccatttacat atccatttgt
     7681 taatgctgta aatgcaactt gagtaataag tcttatatta ttatttacct tagataataa
     7741 cttcatccct cttctcctaa ccaataccaa tacactcaag acaaatcata attgctttag
     7801 ttaatactgt atttgtttct ccacgatatg tacctaatgc aataaatata atactaattg
     7861 caataataga aatgcctttt ttattatctt taataaagtt actcattggc ttttaccatt
     7921 tttagtcttt catctataat ttttttccaa tcttccttac tatttgcacc tacaaccttc
     7981 tcacccacaa agtttccttt cttgtctaca aaataagttg ttggaaactc cataactctt
     8041 ttaaaatcag tttttttaag ttcttcagat acagtcaatt gttggtaagt tgcatctgac
     8101 tttttcataa tgtctttaac taaatttttc tcttcatttg aaagaccagt tctcatatca
     8161 gttttatcaa cttctacaac taatcccttt atagctacat tggaattatt actctcatat
     8221 tcttttgata atgcttcaag ctctggcatt tcacccacac atggtccaca ccaagtagtc
     8281 cagacattaa taagagtaag ttctttattt gaaaatatct cttttgttac cttatttcca
     8341 tcaacatcct ccgtatctaa attactaaac cattcactat tattcttgtt tttttctact
     8401 ggcttagatt cttttttgct acatccagaa atcataccta aaacacaaat acatcctaaa
     8461 actactatga aaaacctttt catatctcac actcctagaa tttatatagt atataaaatc
     8521 gctgcttgaa ataaaaataa cttatcttct atattaaagt aattatattt aataaataag
     8581 agctaattta aaaaaagata tacagttaaa atctatttct tttcagacaa aatcttatat
     8641 atatataata gcttgtaaat cttaag
//
LOCUS       DAJMZY010000137         8627 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.139, whole genome shotgun sequence.
ACCESSION   DAJMZY010000137 DAJMZY010000000
VERSION     DAJMZY010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8627)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8627)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8627
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.139"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            166..2025
                     /locus_tag="OE968_003385"
     CDS             166..2025
                     /locus_tag="OE968_003385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HCP7220621.1"
                     /translation="MKRFLRRIILVLFILLIFISFISIKLIHNVGDYGKLINYVGIVR
                     GASQRLTKLEMNHQPNDELIEYIDEILQELITGHGDYGLVITDCNEYNEDLLLLEKKW
                     EDLNIEIKKVRMKEQNNQLLSISEEFFSLANDTVFKIENFSKEKSNYLMTLIIIISII
                     GILACIILILQYSKKMVRLEKLNVDLKNIAYKDELTGVNTIEKFKLDANQNICIHKDK
                     KFAVFYIDFENFKYINDIFGYDYGDMILKRYANLMMNDIGKYEIFAREIADRFVALRC
                     YVDKEDLVVRQRDVDNELINITNEIKNKHSITVVSGICCIEDVNEKLSIDGLINRANF
                     AQKTVKNKPGTNYAFYNDSIRKKMIEENTIKSRIHEAIEKREFIVYLQPKVNLHSQKI
                     NCAEALVRWLTPDKGIISPAIFIPVLEKNFFIALVDKYVFEEVCKWIRKRLDENKPFV
                     QISVNVSRIQFYNTKFVETYSNIQNKYRIPKNTIEIEFTESVAFENQKHLLEIIHDLH
                     ENGFTCSLDDFGKGYSSLSVLKDLPFDVLKLDSMFFKASLDKDKEKIVIKNIVHMLKE
                     LNITTVAEGIECKEQVEFLRDIGCDLVQGFVFYKPMPILEFEKILDKEFVYNS"
     gene            complement(2317..2916)
                     /locus_tag="OE968_003386"
     CDS             complement(2317..2916)
                     /locus_tag="OE968_003386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HCP7220622.1"
                     /translation="MAIELKKGQKINLTKKENSDLGEILVNLNWNQKVQKKGFFGSLR
                     SSNIDLDLGCLFEMKNGVKGAVQALGNAFGSLDNPPFAQLDGNDRTGSNTQGENLRIN
                     GNKIKDIKRILIYAFIYEGVANWSEADGIVTIKQKQDSDLVVKLDEHKNGYNMCSIAL
                     IENVNDETFSVEKVVKYFKGHREMDTEFHWGLKWVAGRK"
     gene            complement(3019..3816)
                     /locus_tag="OE968_003387"
     CDS             complement(3019..3816)
                     /locus_tag="OE968_003387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HCP7220623.1"
                     /translation="MKFKKLLCLLLCLVLTLAVVGCSKAKDDKKIVVGATLVPGGELL
                     EELKPLIKEKGYTLEVKNFDDYILPNEALNNGEIDANLFQHEPYLKEAVKAKGYKIMA
                     GKKLYVCPAILYSYKIKSVDEFKKGDTIAISNNPSSCSKNLRYLESIGLLTLPKGDGL
                     VSPKDIIENPKGIQFKELDIAQIPSSLPDVTAAFIDTTYAVPAGLDAKKNGIYTAPIN
                     DEYANLLAFRTEDKDSEKIKVLQDVLTSDKARSLIEEKYKGIVIPTF"
     regulatory      complement(3929..4034)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            complement(4126..5112)
                     /locus_tag="OE968_003388"
     CDS             complement(4126..5112)
                     /locus_tag="OE968_003388"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HCP7220624.1"
                     /translation="MLLIYNEKTNPYFNLAMEEYLLKNFDEDLFILWRNEPSIIVGKN
                     QNTLSEINLEYIKEYSIPVVRRQSGGGAVFHDLGNINFTFIACNNNNFSDFRRFTQPI
                     IDLLKTLDVNAEFSGRNDLLIDGKKFSGNAQYNYKNKVMHHGTLLFSSEINDLSKALK
                     VKPIKFEGKGIKSVKSRVTNISEHLHSKMDILEFKDAIMDYLSKTNTDNTNYCLSEHD
                     IKQIEKLTKSKYETWDWNFGNSPKYTLSNELKYSGGNVEFNLNVDKGIITSIKFFGDF
                     FGKCDVAFVENKLIGIRHEENALRNTLDSIEINDYFLGADTDILVSGILGVK"
     gene            5596..7326
                     /locus_tag="OE968_003389"
     CDS             5596..7326
                     /locus_tag="OE968_003389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC family protein"
                     /protein_id="HCP7220625.1"
                     /translation="MRNKKINIIFLTTIMFIMSTVMVFAEEDIDTIALANAEKFGILT
                     LIPPLVAIILAFITKNVIISLLIGILSGSFIIKASGINVFATFIQAFLDLVDRALVSL
                     ADPWNAGIILQVLAIGGVINLVAKMGGAKAIAEALAKRAKSAKGTQLITWFLGLLVFF
                     DDYANSLIVGPMMRPVADKMKISREKLAFIIDATAAPVAGLAIISTWIGLEVGLIHDA
                     FESISIDVDAFGIFLNTIPFRFYNILILAFIVISALLLKEFGPMRKAEIKSRSRKISI
                     DLDEGVEELDDLAPKNGVKLSVWNAIIPIGTLIIVALASFYYSGYTSIMGGDDKALIQ
                     LFTNSPYSFEAIKEAFSASDASRALFQSALVASLVAIIMAVVKKIFTISEAIDVWIDG
                     MKSLVITGVILILAWSLSSVIKELGTAKFLIHLLSGSLPPFLLPSLIFGLGAIISFAT
                     GTAYGTMGILMPLAIPLAYSLNPDMSYVIVSTSAVLTGAIFGDHCSPISDTTILSSMG
                     AGCNHIDHVNTQMPYAIFTAVITIVFGYIPAGLGLPIYIVLPVAIAAIFVGIQIIGKK
                     VDEAEIELVE"
     gene            7436..7516
                     /locus_tag="OE968_003390"
     tRNA            7436..7516
                     /locus_tag="OE968_003390"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:7470..7472,aa:Leu,seq:tag)
     gene            7851..8366
                     /locus_tag="OE968_003391"
     CDS             7851..8366
                     /locus_tag="OE968_003391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HXXEE domain-containing protein"
                     /protein_id="HCP7220626.1"
                     /translation="MEKYIWLFPLLFIFHDMEEIIGFGIWLKKNKSMLDKKYPFISKV
                     YENYSTEGMAFAVFEEFILCIIFCILTVITENQYVYLLWLGSFIAYTLHLVIHIGQSI
                     IIRKYIPSLITSIICLPISIWCISKSIYIVDCEMSTTILYSIIGIIIVALNLKFAQSL
                     IGKFTKWMSNI"
BASE COUNT         3110 a         1067 c         1319 g         3131 t
ORIGIN      
        1 aaaattttgt atatatagag gactctaaag atgaactatg taaaacaagg tttatatatt
       61 ctaattgtat agaaaattta ttgtaaacgc atgtatatta ttagaaaaaa tagtttgaag
      121 gtattcaata aacataaaaa acaatatagg ggataaaggt gttttatgaa gagatttttg
      181 aggagaatta tcttagtttt atttattttg ttgattttta taagttttat ttctattaaa
      241 ttaattcata atgttggaga ttatggaaaa ttgattaatt atgttgggat tgttcgtgga
      301 gctagccaac gtctaactaa actagagatg aatcatcaac caaatgatga attaatagaa
      361 tatattgatg aaatcctaca ggagttgatt acagggcatg gagattatgg tttagtaatc
      421 actgattgta atgaatacaa tgaggactta cttttattag aaaaaaagtg ggaagattta
      481 aatattgaaa ttaaaaaagt aagaatgaaa gaacagaata accagttatt aagtataagt
      541 gaagagtttt tttctcttgc aaatgataca gtgtttaaaa tagaaaactt ttctaaagaa
      601 aaaagtaatt acttaatgac tttaataata attatatcta ttataggtat attagcatgt
      661 atcatattga ttttacaata tagtaaaaaa atggttagac tggaaaaatt aaatgtagat
      721 ttaaaaaata ttgcatataa agatgaacta acaggagtaa atactataga aaaatttaaa
      781 ttggatgcaa atcaaaatat ttgtatacat aaggataaga aatttgctgt attctatatt
      841 gattttgaaa actttaaata cattaatgat atatttggat atgattatgg tgacatgata
      901 ctgaaaagat atgctaatct tatgatgaat gacataggga aatatgaaat atttgcaaga
      961 gaaattgcag atagatttgt tgcgttaaga tgctatgtag ataaggaaga tttagtggta
     1021 agacaacgag atgtagacaa tgaactaatt aatataacaa atgaaattaa aaataaacat
     1081 agtattactg ttgttagtgg aatttgttgt attgaagatg taaatgaaaa attaagtata
     1141 gatggtttaa taaatagagc aaattttgca caaaaaactg ttaagaataa accaggtact
     1201 aattatgctt tttataatga cagtattcgt aaaaaaatga ttgaagaaaa tactatcaag
     1261 agtagaatac atgaagctat tgaaaaaaga gaatttatag tttatttaca gcctaaagtt
     1321 aatttacata gtcaaaaaat aaattgtgca gaagctttag ttcgttggct tactccggat
     1381 aaaggtatta tatcgccagc aatatttatt ccagtacttg agaagaattt ttttattgcc
     1441 ttagtagata agtatgtttt tgaggaggtt tgtaaatgga ttagaaagag gttagatgaa
     1501 aataaacctt ttgttcagat atcagttaat gtttcaagaa tacaatttta taacactaaa
     1561 tttgtagaaa cttattccaa tatacaaaat aaatacagga tacctaaaaa tactatagaa
     1621 attgaattta cagagagtgt tgcttttgag aatcaaaaac atcttttgga aattatacat
     1681 gatttgcatg aaaatggatt tacttgttct ttagatgatt ttggaaaagg ttattcgtct
     1741 ttaagtgttt taaaagattt accatttgat gttttaaagc ttgattctat gtttttcaag
     1801 gctagtttag ataaagataa agagaaaata gtaataaaaa atattgtaca tatgttaaaa
     1861 gaacttaata tcacaactgt tgctgagggc attgaatgca aggaacaagt tgaatttctt
     1921 agggatattg ggtgtgattt agttcaggga tttgtatttt ataaaccaat gccaatatta
     1981 gaatttgaaa aaatattgga taaagagttt gtttataata gctaaaatgt actttataaa
     2041 atatgaacta attaagtaaa attattttgt actgaataaa tttttacttt atttacagaa
     2101 taatgattat ttacagaaaa gcgcgaaaag tgtattcctt taagtgtggg atggatagca
     2161 caaatagagg agaaaaaata ttggccatat aagaatgcat aataatataa atatttgaaa
     2221 ggtcagcatt atataaaaat taaaaagaaa ataaataatt tttctataaa aaagagacta
     2281 tgagaaaatt tactcatagt ctcctaaata atgtatttat tttcttcctg caacccattt
     2341 taatccccaa tgaaattcag tatccatttc tctatgacct ttgaagtatt taactacttt
     2401 ttcaacactg aatgtctcat catttacatt ttctatcaat gctattgaac acatattata
     2461 gccattttta tgttcatcaa gtttgacaac taagtctgaa tcttgttttt gtttgattgt
     2521 tacaattcca tcagcttcag accagttagc tacaccttcg tatataaaag cataaataag
     2581 tattcttttt atatctttta ttttattacc atttattctt aaattttctc cttgtgtatt
     2641 acttcctgtt ctgtcatttc catctaattg agcaaaaggt ggattgtcta aactaccaaa
     2701 ggcatttcct aatgcttgaa cagctccttt tacaccattt ttcatctcaa ataggcaacc
     2761 caaatctaaa tctatattac tgcttcttaa agagccaaaa aaaccctttt tttgtacttt
     2821 ttgattccaa tttaaattaa ctaagatttc acctaaatcg ctattttcct tttttgtaag
     2881 gtttattttt tgtccctttt ttaattctat agccatagta atcttcctcc acaaacatag
     2941 atttatttaa atggtagcac ttaataagtc aatattcaac aagattagaa taataatatt
     3001 aaaattatac taaatatact aaaaagtagg aatcacaata cctttgtatt tttcttcaat
     3061 taagcttctt gctttatctg atgtaagaac atcttgtaga actttaatct tttcactgtc
     3121 tttatcttca gttctaaatg ctaaaagatt tgcatactcg tcatttatag gagctgtata
     3181 aattccgttt ttcttggcat caagaccagc aggtacagca taagtagtat ctataaatgc
     3241 agcagtcaca tctggaagag aagatggaat ttgagcaata tctaactctt tgaattgtat
     3301 tccctttgga ttttctatta tgtccttagg actaactaat ccatcccctt taggtaacgt
     3361 taaaagtcca atactttcaa ggtatctaag gttcttagaa caagaagatg ggttattgct
     3421 tattgcaatt gtatctcctt ttttaaattc atcaacagat tttatcttat aagagtaaag
     3481 tattgctggg catacatata gttttttacc agccattatt ttgtaacctt tggccttaac
     3541 agcttctttt agataaggtt catgttgaaa tagatttgca tcaatttcac cattatttaa
     3601 agcttcgttt ggaagtatgt aatcatcaaa gtttttaact tctaaagtat atcctttttc
     3661 tttaataagt ggttttaatt cttctaataa ctctcctcct ggaactaaag tagcaccaac
     3721 aacaattttt ttatcatctt tagctttaga acatccaacc acagctaaag ttaatactag
     3781 acataataac aaacataata attttttgaa tttcatataa attccctcct gaatataatt
     3841 gattagttaa aaataaaata ccattcttta tcacactgca aaataaaaat aagcctgagt
     3901 ttaaactcag gctttaaaag ctaatttaga ctcatctttc agtataatac tgcaggattt
     3961 agcaccaatg tatataaaaa tatactggtt gctgggtttc atagggccag tcccttcacc
     4021 actctggata agaagtatca atttttaatt atgttataaa tattatcatg attttttacg
     4081 tctgtaaaca taattttata aatattttaa aatctttaat gtattttatt taacacctaa
     4141 aattccagaa actagaatat cagtatcagc acctaagaaa tagtcattta tttcaataga
     4201 atccagagta tttctcaaag cattttcttc atgccttata ccaataagtt tattttctac
     4261 aaatgcaaca tcacattttc caaaaaaatc tccaaaaaat tttatactag ttattatgcc
     4321 tttatcaaca tttaaattaa actcaacatt tccaccagaa tattttaatt catttgaaag
     4381 agtatatttt ggtgaattac caaaattcca atcccaagtt tcgtattttg atttagtaag
     4441 cttttctatt tgttttatat catgctcact caaacaataa ttagtattat cagtatttgt
     4501 tttagaaaga taatccatta tagcatcttt aaattctaat atgtccattt ttgaatgtaa
     4561 atgttcactt atattggtta cacgagattt tacagatttt attccttttc cttcaaattt
     4621 tataggttta acctttaatg cttttgagag gtcatttatt tcagatgaaa ataaaagagt
     4681 accatgatgc attactttgt ttttgtagtt gtattgagca tttccagaaa atttcttgcc
     4741 atctataaga aggtcatttc ttccagaaaa ttcggcattg acatctagtg ttttaagtaa
     4801 atctattatg ggctgagtga atcttctgaa atcactaaaa ttattattgt tacaagctat
     4861 aaatgtaaaa tttatatttc ccaaatcatg aaatacagct ccaccaccag actgtctcct
     4921 aacgacaggt atagaatatt cttttatata ttctaaattt atttcagaaa gtgtgttttg
     4981 gttttttcca acaattatag aaggttcatt cctccataaa ataaataagt cttcatcaaa
     5041 attttttaga agatattctt ccattgctaa attaaaataa gggtttgttt tttcattata
     5101 aattaataac attaaagtag ttcctccata gaattgataa aatttttatt atgaatacaa
     5161 ttaattttat aattcgacaa taatataaaa actcctttaa attagaaatt ttaaaaacta
     5221 ccttgcaaag tttaaataaa taatatatac tcaaaatatg tttaataaaa gtgaatagaa
     5281 gggtagaggc gcaataatct atcagtacta ataaggagtt aagcacagag atttattagg
     5341 aaaggagata ttgccgaagt tttataatcg atgctttaag attatattgc tgggggtaca
     5401 tagaaaatat gtacaactgt cacaggttta tttgtggtga gctatcattt aaggaattat
     5461 attatattta tttttactat tgttgatata ttgtaatgtt taagccttga gtgtttacca
     5521 ctcaaggctt ttttagtttt attgtaacat aataccctgt acagttcaca aaattaaaag
     5581 gagagggaga tttatatgag gaacaaaaaa attaatatta tttttctgac gacaatcatg
     5641 ttcataatgt caacagtaat ggtttttgca gaagaagata tagacactat tgcactagcc
     5701 aatgcagaaa aatttgggat tttaacttta ataccaccat tagttgctat aatacttgca
     5761 tttataacta aaaacgtaat aatttcttta cttataggta ttctttctgg tagttttata
     5821 attaaagcta gtggtattaa tgtttttgcg acatttatac aggcattttt agatttagta
     5881 gacagagctt tagtatcttt agcagaccct tggaatgcag ggataatact acaggttttg
     5941 gcaattggag gagtaataaa tcttgttgct aaaatgggag gagctaaagc tatagctgaa
     6001 gcacttgcta aaagagcaaa gtcagcaaaa gggacacagc ttataacatg gtttttgggg
     6061 cttttagtat tctttgatga ttatgccaat tcactaatag taggtcctat gatgagacct
     6121 gttgcagata aaatgaaaat atcgagagaa aagctagcat ttataataga tgccacagca
     6181 gcaccagttg ctggtttagc tataatatct acatggatag gtcttgaggt tggtttaata
     6241 catgatgctt ttgaaagtat aagtatagat gtagatgcat ttggtatatt tttaaataca
     6301 ataccattta gattttacaa tatattaata ttagctttca ttgtaatatc agcattatta
     6361 ttaaaagaat ttggtccaat gagaaaagct gagataaaat ctagaagtag aaaaattagt
     6421 atagaccttg atgaaggcgt agaagagttg gatgatttag ctccaaaaaa tggagtaaaa
     6481 ttgagtgtat ggaatgctat aatcccaata ggaacattga taatagttgc attagcatca
     6541 ttttattata gtggatatac atctataatg ggaggagacg ataaggctct gatacaacta
     6601 tttacaaatt ctccatattc ttttgaagca ataaaagaag catttagtgc atctgatgca
     6661 tctagagcat tattccagtc tgcacttgtt gcaagtttag ttgctattat aatggctgta
     6721 gtaaaaaaga tttttacaat atcagaagca attgatgttt ggatagatgg aatgaaaagt
     6781 ttagtaatca ctggtgtaat attaatactt gcatggtcat taagttcagt aataaaagag
     6841 ttaggtacag ctaaattttt aatacaccta ttatcaggtt cactaccacc attcttatta
     6901 ccaagtttaa tatttggttt aggagcaata atatcttttg ctactggaac agcttatgga
     6961 acaatgggta tacttatgcc acttgcaatt ccattagcat actcattaaa tcctgatatg
     7021 tcttatgtaa tagtaagtac tagtgcagtt ttaacaggtg caatatttgg agaccattgt
     7081 tctccaattt cagatacaac aatactttct tcaatgggag ctggctgtaa tcatatagac
     7141 catgttaaca ctcaaatgcc atatgctata tttacagcag taatcactat tgtatttggg
     7201 tatataccag ctggacttgg attgccaata tatatagtat taccagtggc aatagctgct
     7261 atatttgtag gtattcaaat aattggtaag aaagttgatg aagcggaaat agaacttgta
     7321 gaataaagat ataaataagt ttcacctttt attatcacta ttttgttagt ttttagataa
     7381 ttttaaaaag ttattgaaaa taatggcgaa atatagtaaa ataaaagagt gataagcgga
     7441 tgtggcggaa ttggcagacg cactagactt aggatctagc gccattggcg tgggggttcg
     7501 actcccttca tccgcacttt acagtactta attgtactga aaaaaactgg ggttgctggc
     7561 tttcggagtg ggctatcccg tttttatttt tttgtatata taatagattg gcactttagt
     7621 ataaggtgct ttttttatag gcaaaaacag tacatttatt tctgttttat tatcattcat
     7681 ctattagaat atactttagt taagaatgtg ttaataagca gtgttcacat tcttgataaa
     7741 atgtggaata atatgtattt ttactaagac ggaaatgaaa taattaaacc attaaataat
     7801 attataagat gatgaataag tagataaatc aaattttgta ggaggatatt atggaaaaat
     7861 atatatggtt gtttccatta ctttttattt ttcatgatat ggaagagata ataggttttg
     7921 gaatatggct taaaaaaaat aaatcaatgc ttgataagaa gtatccattt atcagtaaag
     7981 tttatgaaaa ttatagtact gaaggcatgg catttgctgt gtttgaagaa tttattttat
     8041 gcattatttt ctgtatactt acagttataa cagagaatca gtatgtatat ctactatggt
     8101 taggtagttt tatagcatat accttacatt tggtaattca tatagggcag tcaatcataa
     8161 taagaaaata tataccttca cttattacca gtatcatatg cttaccaata agcatttggt
     8221 gtataagtaa gagtatttat atagttgatt gtgaaatgag tacaacaatt ctgtacagta
     8281 taattggcat tataattgta gcattgaatt taaagtttgc acagtcgctg attggaaaat
     8341 ttacaaagtg gatgtcaaac atataaattt tagtttattg gacagttcaa ggaatcagaa
     8401 attggaattt tatagtatta atattttatg gtattaatat aatgtataaa attttatagc
     8461 aatgtatttc ataagtataa agtgactaga attttaagaa atatacaaat tctataaaaa
     8521 ctaaataatt tcaagtatat tttaaaaatc ttatttttca caagtttaaa attgtaaacg
     8581 atttcatcaa gtctatgaat atacttttaa catgttatag taaatct
//
LOCUS       DAJMZY010000138         8436 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.141, whole genome shotgun sequence.
ACCESSION   DAJMZY010000138 DAJMZY010000000
VERSION     DAJMZY010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8436)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8436)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8436
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.141"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            286..1272
                     /locus_tag="OE968_003392"
     CDS             286..1272
                     /locus_tag="OE968_003392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCP7220627.1"
                     /translation="MKKITINDIANLAGVSKSTVSRYLNNKDISDSTKEKIKTIIDEY
                     GYEPNAFAQSLRAKKTYFIGIITPCLDSFVKSKIMMAIDEELKKLKYTSLIINTNRKI
                     RSEIDSISKLASLKVDGIILIGTEITKEHKNEIEKLDIPIVVVGQKVDGINSIVNDDY
                     GAGYKMGQYIANKGYKNIVYLGVDESDISVGLNRKNGVLNGLKDKGYDAKVFYTDFDQ
                     EMSIQRSGEMLESENPDIIICATDNIAIATMKEINKRGKSIPQDISVAGFGGYDVLSI
                     ISPKLTTIKFENKNAGKVAANTIVNLIQERKEPLLKEIKFELIEGESTINKN"
     gene            1441..1589
                     /locus_tag="OE968_003393"
                     /pseudo
     CDS             1441..1589
                     /locus_tag="OE968_003393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423822.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIB"
     gene            1608..3089
                     /locus_tag="OE968_003394"
     CDS             1608..3089
                     /locus_tag="OE968_003394"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HCP7220628.1"
                     /translation="MYKEPKYRTILESTKEELNKLRNISLNDKYKPLFHIHPQHGLLN
                     DPNGLAYYNGKYHVFYQWYPYDATHGMKHWAYVSSDDFVNWNREDVALIPIESYESHG
                     AYSGNAIEVDGKLHMYYTGNIKYSAEDRYAYQNLAIMNKDGKITKYENNPIVSEIPKG
                     YTGHVRDPKVFKRKDKYFMLLGAQTSDKKGVIIVYESKNSIDWNFKGELNVKNIDEDF
                     GYMWECPDYINIDEKDILIFSPQGVEPKGFDYQNIYNVVYAIGNMDLDNLTFEIDTMK
                     ELEKGFDFYAPQTFIKDSQIILFAWAGMGEVLYPTDKNKWAHCLTVPRKLNIKNNKLL
                     QMPVDELIKLRYDETSGQNTIKNNINIIENDENVYELNINIKNIDSNKFGLELFSSQD
                     EGVKLEFNKLGNIVTLDRSNFKKVFGVEYGTNRKEYINIDENTNIKVLADRSILEIFI
                     NEGEVVFTSRIFAKENSNQIRVYSDKIVEYEYTKFKLKQGIEL"
     gene            3115..4086
                     /locus_tag="OE968_003395"
     CDS             3115..4086
                     /locus_tag="OE968_003395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate kinase"
                     /protein_id="HCP7220629.1"
                     /translation="MKKVISIGEALIDFIPNQNGGKLKNVSEFRRVAGGAPANVSAVV
                     AKLGGKSSFISKLGKDAFGDYIIDVLNEVNVNTDYVLRTSKANTGLAFVSLKEDGNRD
                     FSFYRNPSADMLLEADEVKKEWFNNCHILHFCSVDLIDSPMKLAHKKAIEYALESNSI
                     ISFDPNIRLPLWDSEQSCKKAISEFLPFAHIVKISDEELEFITGENDIEKSLHKLFVG
                     NVELVLYTKGKDGVDAYTKKVKGMCKGVKVNAIDTTGAGDSYIGSFLYTLLYKQITLN
                     DIKEMKQETLNEYLEFSNYYAARSTTIKGAISSYATKEEITEFIKNL"
     gene            complement(4342..4944)
                     /locus_tag="OE968_003396"
     CDS             complement(4342..4944)
                     /locus_tag="OE968_003396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HCP7220630.1"
                     /translation="MEVCILMGSPKKKGNTAAILKPFIEELENYNSNIEVIWLYDCKI
                     EPCIACKKCQDNLFDFGCYCKDDVQKIFKKILMCDLIVFATPIYSWYCTSPMKALLDR
                     LVYGMNKYYGNEKGPALWAGKSVALITTCGYRPEKGADIWENGMKRYCKHSQLKYIGM
                     LVERDLGKPNFMNKEKEEHSRQFAKQIYYILSNSIELDNC"
     gene            5225..6436
                     /locus_tag="OE968_003397"
     CDS             5225..6436
                     /locus_tag="OE968_003397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal-dependent decarboxylase"
                     /protein_id="HCP7220631.1"
                     /translation="MYSNEDYKFIEENAPCYIYDETNIIEKCKELKNNILGFDFLYSI
                     KTNPYNKIVKSIAEQGFGADASSTNEVMISSKCGVSKDDIYYSSPGKTEIDIETVLDK
                     CIIIADSITEIELINKISKKHNQKVKIGIRINPDFTMDDDSAKSSKFGIDIEDMSSVF
                     KMLSMCDYVSVVGIHIHIKSQVLDFEKLGHYYEKCFFIALNLNKSKYINIEFINFGSG
                     LGVAYDNLRENPLNLKELSKLTQKIAFTNSNTLKSRLLIESGRFIVCKSGNYYVKIVD
                     IKVSRGKKYLIVKNGLNGFMRPIISNLIENITCGVELEGQEPLYTSNHAFSLSVLNNL
                     KEEEYVNVVGNLCTSLDVIANNVKLKKANIGDLISISNAGSYSYSLSPLLFSSYEFPK
                     QYYKRKDGYIE"
     gene            6504..6701
                     /locus_tag="OE968_003398"
     CDS             6504..6701
                     /locus_tag="OE968_003398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug transporter"
                     /protein_id="HCP7220632.1"
                     /translation="MELWKRNLFVCWIGMFFSSIGMSQIAPILPLYIKQLGVTDVSLI
                     QQYSGIIFGCTFVVAAFFSPI"
     gene            6735..7706
                     /locus_tag="OE968_003399"
     CDS             6735..7706
                     /locus_tag="OE968_003399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCP7220633.1"
                     /translation="MLLRASIGMGIVIFTMAFVQNVYQLLGLRILQGVFTGYATACTT
                     LIATQTDKNHSGWALGTLATASTTGSLIGPTVGGYIESILGLKSTFIITGGLLFVSFI
                     ISILFVVDNFKPKEIKESISIPKEQLNILPNKFLIASIFVTTFITQLALYSIEPIVTI
                     YISQLTNFASNVALIAGLTFSASGLANLLAAQKLGKMSDKIGPQKVLLISLLWAGIIF
                     IPQAFVKTAWQLMLLRFLLGLSVAGLNPSVNSLLKKIAPEEYVGKIFGYNASAQYIGC
                     SSGAFLGGQISAHLGIRTVFFSTSLLLFRNALWMYKFTGLFIKDKTK"
     gene            7893..8270
                     /locus_tag="OE968_003400"
     CDS             7893..8270
                     /locus_tag="OE968_003400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HCP7220634.1"
                     /translation="MTISKIPQAELKVMKFIWEKNDTVTSKETIEAMERKYGWKQTTT
                     LTLLSRLVKKHFLSAEKIDRYTHYTIVVGHKEYLSVETKDFLSNIHDNSLQSLISALH
                     DDEVVDKDMLDLFESHFKNLEEE"
BASE COUNT         3428 a          881 c         1364 g         2763 t
ORIGIN      
        1 ttaagtgttt atcgataagg ctatggttgt aaaaatcata gccttatttt tatattataa
       61 ataaattaga gtatttatca attcatagta gataaaattg aaattaaata taacaacaaa
      121 aaatgaaaat tacaattaat ttaatgttaa agactcaatt atttggatgt ggaatggata
      181 gtacaagtag tatataaaaa gtattgactg gacaaataac tatattttat tttaaatata
      241 taatataatg taataaaata tatcaaatgt agaaggtgat aacctatgaa aaaaataaca
      301 ataaatgata ttgctaactt ggcaggagta tctaaaagta ctgtatcaag atatctaaac
      361 aataaagata tcagtgattc tactaaagag aaaataaaga caataataga tgaatatgga
      421 tatgagccga atgcatttgc tcaaagtttg agagctaaaa aaacatattt tattggtatt
      481 ataacaccgt gtttagattc ttttgtaaaa tctaaaatta tgatggcaat agatgaagaa
      541 ctcaaaaaat taaaatatac atcactaatt attaatacta atagaaaaat aaggtcagaa
      601 atagatagta tatcaaagtt agctagtcta aaagttgatg gaataatact aattggtacc
      661 gaaataacta aagaacataa gaatgaaatt gaaaagttag atataccgat agttgtagtt
      721 ggacaaaaag ttgatggtat caatagcata gtgaatgatg attatggagc aggctataaa
      781 atgggtcaat atattgctaa taaaggttac aaaaacattg tatatttagg tgttgatgaa
      841 agtgatatat cagttggttt aaatagaaaa aatggagtac ttaatgggtt aaaagataaa
      901 gggtatgatg caaaagtatt ttatactgac tttgaccaag aaatgtctat acaaagaagt
      961 ggagaaatgc tagaaagtga aaatccagat ataataatat gtgcaactga taatatagca
     1021 atagcaacaa tgaaagaaat caataagaga ggtaaaagta taccacaaga tatatctgta
     1081 gctggatttg ggggatatga tgtattgtct attataagcc ctaaacttac aacaataaag
     1141 tttgaaaata aaaatgcagg taaagtagca gcaaatacga tagtaaattt aatacaagaa
     1201 agaaaagaac cactattaaa ggagattaaa tttgaattaa tagaaggtga aagtacaata
     1261 aataaaaatt aagatacaca ttacatatat tagtaatgtg tattttttta ctaaaaaaac
     1321 tataattcta aaaattagga aaactttttt gaaagaaata ttgcatctga aataaattta
     1381 tgctaatctt taattaaacc ggtttcgaaa ccggtttaat taaaccgata gaatagcaaa
     1441 atgagtgcaa aaataactga ttgtaacaaa gtatcaaagt aattattgga gtacatagga
     1501 ataaacaaaa tataaaagat gtagcacatt gtgtaataag actaagaatt gttttagata
     1561 gcaataataa agcaaatata aaattataaa agaaaaggaa taaaaatatg tacaaagagc
     1621 ctaaatatag aaccatatta gaatcgacaa aagaagaatt aaataaatta agaaatatat
     1681 ctttaaatga taaatataaa ccactatttc atatacatcc acaacatgga ctacttaatg
     1741 acccaaatgg attagcatat tataatggta agtaccatgt attttatcaa tggtatccat
     1801 atgatgcaac tcatggaatg aagcattggg cttatgtaag ttctgatgat tttgtaaact
     1861 ggaatagaga agatgtagca ttaataccaa tcgaaagtta tgaatctcat ggagcatatt
     1921 caggtaatgc gatagaggta gatggaaaat tgcatatgta ttatacaggg aatataaaat
     1981 atagtgcaga agatagatat gcatatcaaa acttagctat aatgaacaag gatggtaaaa
     2041 taactaaata tgaaaataat ccaatagtaa gtgaaatacc aaaaggatat acaggacatg
     2101 taagagaccc aaaagtattt aaaagaaagg ataaatactt tatgttactt ggagcacaaa
     2161 caagtgataa aaaaggagtt ataatagtat atgaatctaa aaactctata gattggaatt
     2221 ttaaaggaga attaaatgta aaaaacatag atgaagattt tggttacatg tgggaatgtc
     2281 cagattatat taatatagat gaaaaagata tattaatatt ttcaccacaa ggagtagaac
     2341 ctaaaggatt tgattatcaa aatatatata atgtagtata tgctattggt aatatggatt
     2401 tagataattt aacatttgaa atagatacaa tgaaagaact ggaaaaagga tttgatttct
     2461 atgctccaca aacatttata aaggactcac aaataatact atttgcatgg gctggaatgg
     2521 gagaagtttt ataccctaca gataaaaaca aatgggcaca ttgtctaact gttccaagaa
     2581 aattaaatat aaaaaataat aagctattgc aaatgccagt agatgaatta attaaattaa
     2641 gatatgatga aacaagtggg caaaatacta taaagaataa tattaatatt atagaaaatg
     2701 atgaaaatgt atatgagctt aatattaata taaaaaatat tgacagcaat aaatttgggc
     2761 tggaattatt ttcatcacaa gatgaaggtg taaaattaga atttaacaaa ttaggaaaca
     2821 ttgtaacttt agacagaagc aactttaaaa aagttttcgg tgttgaatat ggaacaaata
     2881 gaaaagaata tataaatatt gatgaaaata ctaatatcaa agtactagcg gatagaagta
     2941 ttttagaaat ttttataaat gaaggagaag tagtatttac tagtagaata tttgctaaag
     3001 aaaattctaa tcaaataagg gtttatagtg ataaaatagt agagtatgag tatactaaat
     3061 ttaaattaaa gcaaggtatt gaattataaa aacacattat aaggggtaga aaagatgaaa
     3121 aaagtaatta gtataggaga agctttaata gactttatac ctaatcaaaa tggtggtaaa
     3181 ttaaaaaatg tatcagaatt tagaagagta gcaggaggag ctccagcaaa tgttagtgct
     3241 gttgtagcaa agcttggagg aaaatcgagt tttatatcta agttaggaaa agatgcattt
     3301 ggtgattata taatagatgt attaaatgaa gtaaatgtaa atactgatta tgtattgaga
     3361 acaagtaaag caaatacagg acttgctttt gtatcattaa aagaagatgg taatcgtgat
     3421 ttctcatttt atagaaatcc aagtgcagat atgcttttag aagctgatga agttaaaaaa
     3481 gagtggttta ataattgtca tatcctacat ttttgttcag tagatttaat agatagtcca
     3541 atgaaattag cacataaaaa agcaatagaa tacgcacttg aaagtaatag tataataagc
     3601 tttgacccta atataagatt acctttatgg gatagtgagc aatcttgtaa aaaggcaata
     3661 tcagaatttt taccttttgc tcatattgtt aagatatctg atgaagaatt agaatttata
     3721 acaggagaaa atgatataga aaaatcatta cataaactct ttgtggggaa tgttgaacta
     3781 gtattatata caaaaggaaa agatggagta gatgcataca ctaaaaaagt aaaaggtatg
     3841 tgtaaagggg ttaaagtaaa tgcaatagat acaaccggag caggagattc ttatataggt
     3901 tcatttttat acaccttatt gtataaacaa ataacattga atgatataaa agaaatgaaa
     3961 caagaaacgt taaatgagta tttagaattt tctaattatt atgcagctcg tagtacaact
     4021 attaaaggtg cgataagttc atatgcaaca aaggaagaaa taactgaatt tataaaaaat
     4081 ttatagtagg aatgagtaat aggttttgaa ggaagtaaca tgtaaagagt ttttaaggat
     4141 gtttactatg aaaataatta acatataaaa agcaataagg aggctgtctc aaaatagaga
     4201 taagcctctt tatcattgtt gaaatgataa aaaatatttt aattattgtt actttttaga
     4261 agaatatata tcttatttta aataagcaaa ttatgtaaga tttatttata ttatcaatac
     4321 tttacttgga gtattatgtc tttagcagtt atctaattca attgaattag ataaaatata
     4381 ataaatttgt tttgcaaatt gacgagaatg ttcttctttt tctttattca taaaattagg
     4441 tttacctaaa tcacgttcaa caagcattcc tatatatttt aactgtgaat gcttacagta
     4501 gcgcttcata ccattttccc aaatatcagc acccttttca ggtctatatc cacatgttgt
     4561 aataagtgct actgattttc ctgcccatag agcggggcct ttctcattac catagtattt
     4621 attcattcca tacaccaatc tgtcaagtag tgctttcatt ggagaagtgc agtaccaaga
     4681 ataaattgga gtagcaaaaa caattaaatc acacataaga attttcttga aaattttctg
     4741 aacatcatct ttacaataac atccaaaatc aaataagtta tcctgacact ttttacaagc
     4801 aatacatggc tctattttac aatcatataa ccatattact tcaatatttg aattataatt
     4861 ttctaattcc tcaataaaag gttttaaaat agcagcagta ttaccttttt tcttaggact
     4921 tcccataaga atgcatactt ccatattgat acctccacag tattttaaaa tagtttttag
     4981 tgcttaatat agttttagga tactatgaga atacgttaac aacaatacac tttgtatatt
     5041 tgtaataaaa ttgaaacaaa ttgttttatc aataaaagtt ggaatgtatc tataattaaa
     5101 aatattttag gtatgttttt acatatatgt gtgtagttaa ctatggtaat ttattgtaaa
     5161 attatcttat aggattataa ttgcttaatt tatgattata tttaaaatct tggaggtaaa
     5221 aaatatgtac tcaaatgaag actataaatt tatagaagaa aatgcaccat gttatatata
     5281 tgatgagact aatataattg aaaaatgtaa ggaattgaaa aataatattt taggttttga
     5341 ttttttatat tctataaaaa caaatccata taacaaaatt gtaaaaagca ttgcagagca
     5401 aggttttgga gcagatgctt cttcaactaa tgaagttatg atttcatcaa aatgtggagt
     5461 ttctaaagat gatatttatt attcatcacc aggcaaaaca gagattgata tagaaactgt
     5521 tttagataaa tgcataatta ttgcagatag tattacagaa atagaactta taaataagat
     5581 atctaaaaag cataatcaga aagttaaaat aggaataaga ataaatcctg attttactat
     5641 ggatgatgat agtgctaaat caagcaaatt tggtatagat atagaagata tgagcagtgt
     5701 ttttaagatg ttaagtatgt gtgattatgt atctgtagtt gggattcata tacatattaa
     5761 atctcaggta ttggattttg aaaagttagg acattattat gaaaaatgtt tttttatagc
     5821 tttaaattta aataaaagta agtatattaa tattgaattt ataaattttg gtagtggact
     5881 tggagtagct tatgataatc ttagagaaaa tccacttaat cttaaagagc tttcaaaatt
     5941 aactcaaaag attgctttta ctaattcaaa cacactaaaa tcaagacttc ttattgaatc
     6001 aggacgtttc atagtttgta aatcaggtaa ttattatgtt aaaattgtag atattaaagt
     6061 atcaagaggg aaaaaatatc ttattgtaaa aaatggactt aatggattta tgagacctat
     6121 tatttctaat ttaattgaaa atattacttg tggagtagaa ttagaaggtc aagagccatt
     6181 atatacatca aatcatgcct tttctctttc agtattaaat aatttaaaag aagaagagta
     6241 tgtaaatgtt gttgggaatc tctgtacatc attagatgta attgcaaata atgttaaatt
     6301 gaaaaaagca aacataggag atttgatttc aattagtaat gctggaagtt actcctattc
     6361 tttatcaccg ctattatttt caagttatga atttcctaaa caatattata aaagaaaaga
     6421 tggatatatt gagtaaacaa tagcataaat taataaactt agtattattg aaaaaattta
     6481 aaatgcaggg ggtgtaattc tatatggaat tgtggaaaag aaatttattt gtatgttgga
     6541 taggtatgtt ttttagttct atagggatga gccaaatagc acctatactt ccattatata
     6601 ttaaacagtt gggggtaact gatgttagtt taatacaaca gtattcaggt ataatttttg
     6661 gatgtacctt tgtagtagca gcattctttt cgccaatttg agggaaagct gctgataaat
     6721 atggaagaaa atcaatgctt ttacgtgcaa gtattgggat gggaatagtt atatttacca
     6781 tggcgtttgt tcaaaatgtt tatcagttat taggattaag aatacttcaa ggagttttta
     6841 cgggttatgc tactgcatgt actactctta ttgcaacaca gacagataaa aatcattcag
     6901 gatgggcttt gggtactctt gcaactgcat caactactgg ctcattaatt ggtccaacag
     6961 taggaggata tatagaatca atcttaggtc ttaaaagtac atttattata acaggaggat
     7021 tgttgtttgt atcatttatc atctctattt tatttgtagt agataatttt aaacctaaag
     7081 aaataaaaga atcaatttct atacctaaag aacaattaaa tatattgcca aataaatttt
     7141 taattgcatc tatttttgta accacattca ttactcaact agctttatac tctatagaac
     7201 caattgtaac catatatata tcacaactta caaattttgc atcaaatgta gctttaatag
     7261 ctggattgac attttctgca tcaggattag caaatttatt agcagctcaa aaacttggaa
     7321 aaatgtcgga taaaataggt cctcaaaaag tattgttaat ttcactttta tgggctggga
     7381 ttatatttat accacaagct tttgtaaaaa ctgcatggca actgatgttg ttgagatttt
     7441 tattagggtt gtcagttgca gggcttaatc cttctgttaa cagcttgctt aaaaaaattg
     7501 caccagaaga atatgtggga aaaatatttg gatataatgc atctgcccag tatataggct
     7561 gttcatcagg agcattttta gggggacaaa tatcagcaca tttaggtatt agaacagtat
     7621 ttttttcaac aagtttattg ttgtttagga atgcactttg gatgtataaa tttactggat
     7681 tgtttattaa agataagact aaataatcat actatttaca tttctaattt tatgatgtaa
     7741 aataaatatt ttttatgtaa tttatcatag aattatataa aaaataaccc tatggtaaaa
     7801 attggaaaat attattatcg acaaaatctt tgacttaaaa actatattgc gatagtatta
     7861 atttaataaa agtttgagag gggcgtaagg ttatgacaat ttcaaaaata ccacaagcag
     7921 aattaaaagt tatgaagttt atttgggaaa aaaatgatac agtaacatca aaagaaacta
     7981 ttgaagctat ggaacgaaaa tatggttgga aacaaacaac tacattgaca cttttatcaa
     8041 gacttgttaa aaaacatttt ttaagtgcag aaaaaataga tagatacact cattatacaa
     8101 tagttgttgg acataaggag tatttaagtg ttgagacaaa agatttttta agcaatatac
     8161 acgacaattc tttacagagt ttaatttcag cactacatga tgatgaagtt gttgataaag
     8221 atatgttgga tttatttgaa agtcatttta aaaatttaga agaagagtaa ttatatcagg
     8281 atagaactct aagaatttaa ttaatctatg gctgaaaacc ataaatggta ttatttaatc
     8341 agctactcac tattcataaa gtaatattaa ataggttctc taattagtaa aatgcctaaa
     8401 ataattggaa tagggagtat caagttaaat gatacc
//
LOCUS       DAJMZY010000139         8417 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.142, whole genome shotgun sequence.
ACCESSION   DAJMZY010000139 DAJMZY010000000
VERSION     DAJMZY010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8417)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8417)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8417
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.142"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            288..1301
                     /gene="aroF"
                     /locus_tag="OE968_003401"
     CDS             288..1301
                     /gene="aroF"
                     /locus_tag="OE968_003401"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003452924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HCP7220635.1"
                     /translation="MIVVLKMGADKNEVKKLIEAIGREGVEVNPIDGTELTVLGLVGD
                     TSKIDAKRIEANKVVEKVMHVVEPFKKANRKFHPEPSIINVNGMEIGSKKIAMIAGPC
                     SVETEDQIVSIAKDVKKSGAGFLRGGAFKPRTSPYAFQGLKYDGLDLLKKAKEKTGLP
                     IVTEIMSTQDIDIFEENVDVIQVGARNMQNFDLLKELGKTNKTILLKRGLSATIEEWL
                     MSAEYIMAGGNENVVLCERGIRTFETYTRNTLDLSAILAVKKLSHLPVIVDPSHAAGK
                     SWMVDSLSKAAIAVGADGLIIEVHNDPAHALCDGKQSIKPNEYDELISELKTIASAVG
                     REI"
     gene            1323..2387
                     /locus_tag="OE968_003402"
     CDS             1323..2387
                     /locus_tag="OE968_003402"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HCP7220636.1"
                     /translation="MEEKLLVNLKENSYNIFIKKNILKNIGEEIKKIYFGNKIFIVTD
                     ENIAKLYLDKVKNNLSESGFEIKSLILKSGEETKSFNTLPKIYDSLLDFKLTRKDLII
                     TLGGGVIGDLGGFAAATFLRGISFIQIPTSLLAQVDSSVGGKVGVDLERGKNLVGSFY
                     QPKAVFIDPNVLLSLPEKFYRDGMAEVIKYGCIKDKTFFNKLLSLKNREEVMQHIEYI
                     IHKCCFIKKTVVEADEKDFGDRMLLNFGHTLGHAIEKYYNFTGYTHGEAVAIGMYKIT
                     LESEKIGITKKGTSELIKSILMNYNLPYEIELRDNKSIVDAISLDKKNLGDTLKIILL
                     KDIGESIIYNTTSKFFQEVR"
     gene            2387..3700
                     /gene="aroA"
                     /locus_tag="OE968_003403"
     CDS             2387..3700
                     /gene="aroA"
                     /locus_tag="OE968_003403"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HCP7220637.1"
                     /translation="MGSLKIYPSKLSGDVKIPPSKSMAHRAVICSSLSNGKSRISNID
                     FSDDIIATIRAMTSLGAIIEKKEDILEISGIFSKEGILNRENQLNQPKLTIDCNESGS
                     TLRFLVPISLAFDGVKRFIGRGNLGKRPLDTYYEIFDRQNIKYSYKENQLDLIISGKL
                     KPDEFRVKGNISSQFITGLLFILPTLESDSKIIITTELESKGYLDLTLSTIKDFGVEI
                     INNNYKEFIIKGNQTYKARDYKVEGDYSQGAFYLSADAIGEDISILDLKEDSLQGDSE
                     VVEILSRMGMEILREGNKIKGITNGLNGTLIDASQCPDIIPVLSVVASLSIGRTTIIN
                     AGRLRIKECDRLHAINVELNKLGANIEEKEDSLIIEGVSKLNGGVEVWSHKDHRIAMT
                     LAIASCRCDKPIILKDFECVSKSYPHFFKDFKMLGGRIDEWNMGK"
     gene            3678..4757
                     /gene="aroC"
                     /locus_tag="OE968_003404"
     CDS             3678..4757
                     /gene="aroC"
                     /locus_tag="OE968_003404"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HCP7220638.1"
                     /translation="MSGIWGNNLKVSIFGESHGNAIGINIDGLPSGIELDLDNIDKEM
                     KRRAPGKNSISTSRNESDIPEILSGYFNGRTTGTPLCAIIRNSDTRSKDYGELKNLMR
                     PGHADFTGNVRYSGFNDYRGGGHFSGRITAPLVFCGAICKQILSQKGIEIGAHIKKIK
                     NIEDMSFDYVNISKQQLSNLQTLELPLLDLSKEEAMKNTIIDAKNQGDSVGGIIECAV
                     VGINVGLGNPFFDSVESTLSHLLFSVPAVKGVEFGLGFELADMYGSQSNDEMYYEGNQ
                     VKSKTNNNGGIIGGITTGMPIIFKVAIKPTPSISRQQNTVNIKDKKDDILYIKGRHDP
                     CIVQRAIPVIEAVTAIGIFDLMKGR"
     gene            4760..5956
                     /gene="pheA"
                     /locus_tag="OE968_003405"
     CDS             4760..5956
                     /gene="pheA"
                     /locus_tag="OE968_003405"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HCP7220639.1"
                     /translation="MEDLTRYRNEIDNIDKELIQLFEKRMNTVLEIARHKMKNNTTIL
                     QKDREEKVLSRAVDNLDNKAYSQETVQFFNSIMEISRGLQKRFIDNDGEQKIEFSLDS
                     SNKNFDLSNVNKYKSLKDELNKKNILVGFPGKSGSFTEEALNKFFNKKISKKQFKEFE
                     DVFIALKNKEINYGIIPIENSSTGAISETYDLLRKYGFYIVGEECIKIDQNLIGIKDT
                     KLEDIKEIYSHPQGIGQCSEFLKQNSTWKLIPFNNTATSAELVRKLQDKTKAAIASKK
                     AASIYGLEIISPCINDIANNYTRFVVISNQIHIEEESNKMSVVFSVEHEAGKLYKVLG
                     YFAKNNINMTKIESRPMKNASWRYFFYIDFECSIYNAKVYDLLELIEHNTAYFKFMGV
                     YKNKTE"
     gene            6003..6812
                     /gene="aroE"
                     /locus_tag="OE968_003406"
     CDS             6003..6812
                     /gene="aroE"
                     /locus_tag="OE968_003406"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HCP7220640.1"
                     /translation="MNFFGLVGEKLSHSVSPQIHKRVFEILNIESAYKNFEISKEDIS
                     KLDGAIKLLGIQGVNVTVPYKERIMKYLDFISPEAKRIGAVNTILLRENMLYGYNTDY
                     FGLDSMFKMANIDVQGKVAVILGTGGASKAALTYFIDSGIEKLYVSTRKKDDKKLLNS
                     KAILIDYEELKHIKGDIILNATPVGMYPNVGISPVSKSIIQNFDILIDLIYNPGETEF
                     LRIGNSMGKKTCDGLYMLVGQAIKSQEIWQDTKIDNSILDVIYNELKLEFL"
     gene            6824..7357
                     /locus_tag="OE968_003407"
     CDS             6824..7357
                     /locus_tag="OE968_003407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HCP7220641.1"
                     /translation="MINKTKEKLILIGMPGSGKTTIGKLLAKEYNCSFCDMDDYIIQI
                     SQKSIAELFSEGEDIFRNYETQACRELSISDKTVISTGGGVIKKDINMEILKETGIII
                     FIDRPIQKILEDININSRPLLKNGKDRLYNLYNERINLYKKFSDIEILNDKSLNNAVY
                     NITNAVSENFKFDFKEK"
     gene            7378..8217
                     /locus_tag="OE968_003408"
     CDS             7378..8217
                     /locus_tag="OE968_003408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HCP7220642.1"
                     /translation="MNIVIVGLGVIGGSFAKALKKAGYENVFGVDVDLETLKKAEKAK
                     IIKKGCTTGKELFKKADLIILSIYPRLVVDFLNNNKNFFKKGTIITDTTGIKETLIND
                     VLQIIPDDIDFIFGHPMAGREKKGIDFASEQVFNGANYIITPTGRNNIKNLELVENLI
                     LEIGFKRVKKLTSQKHDEIIAFTSQLPHVMAVALINSDEEGRDTGKFIGDSYRDLTRI
                     ANMNEDLWSELFLGNRDNLLKVIENFESEVNLVKEAIFNNDKNKLIEYFKKSSIRREA
                     LEK"
BASE COUNT         3445 a          844 c         1510 g         2618 t
ORIGIN      
        1 ctatgaaagg aatattaaaa gaactaacag caaaacttta tagctttttt tactttatgt
       61 tctggggctt ttattttagc gctggctatt tcttttacaa aaatatatgt acttcctttc
      121 tggtgaggcc ttattttagt gattttgagc ataagtaaat tttataaaaa tgattatttt
      181 atatatttat ataagattta gtgcttgata gattatttta gagaactcat tagtgagttc
      241 tcttttttat tttaaatata aaattataat attgggaggt agtaaaaatg atagtagtat
      301 taaaaatggg agcagataaa aatgaagtta aaaaattaat tgaggctatt gggagagaag
      361 gagtagaagt taatcccata gatggaacag aattaactgt tttaggttta gttggagata
      421 ctagtaaaat agatgccaaa agaatagaag caaataaggt agttgaaaaa gttatgcatg
      481 tggtagagcc ttttaaaaag gccaatagaa aatttcatcc agaaccttca atcataaatg
      541 ttaatggaat ggaaattggt tcaaagaaaa ttgctatgat agctgggcct tgttctgttg
      601 aaacagaaga ccaaatagta tctatagcta aagatgtgaa aaaatcaggt gcaggatttt
      661 tgagaggtgg agcattcaaa ccaagaacat caccatacgc tttccaagga ttgaaatatg
      721 atggattgga tttattaaaa aaagcaaaag aaaaaacagg gcttcctata gttacagaaa
      781 taatgtcaac acaagatata gatatatttg aagaaaatgt agatgtaatt caagttggag
      841 ctagaaacat gcaaaacttt gatttattaa aagaattagg taaaacaaat aaaacaatac
      901 ttttaaaaag aggattatct gctacaattg aagagtggct aatgtcagca gagtatataa
      961 tggctggagg aaatgaaaat gtagttcttt gtgaaagagg tataagaact tttgaaacat
     1021 atactagaaa tactttggat ttaagtgcaa ttttagctgt gaagaaactt agtcatttac
     1081 cagttatagt tgacccaagt catgcagcag gtaaatcatg gatggttgac tctttatcta
     1141 aggcagcaat tgcagttgga gcagatggtc taataatcga agttcataat gacccagcac
     1201 atgcactttg tgatggaaaa caatcgatta agccaaatga atatgatgaa ttgataagtg
     1261 aattaaagac tatcgcatca gcagttggta gagaaatata atctataaaa ggatggttaa
     1321 acgtggaaga aaaactatta gtaaatttaa aagaaaatag ctacaatata tttattaaaa
     1381 aaaatatact aaagaatata ggagaagaaa taaaaaaaat atattttgga aataagattt
     1441 ttattgtaac tgatgaaaat atagcaaaat tatacttgga taaagtaaaa aataatttaa
     1501 gtgaatctgg atttgaaatt aaatctttaa tattaaaatc tggtgaagaa acaaaatcat
     1561 ttaatactct tcctaaaata tacgatagtt tacttgactt taagttaact agaaaagatt
     1621 tgattattac tttaggagga ggggtaatag gtgatttagg tggatttgca gcagcaactt
     1681 ttttaagagg tataagtttt attcaaattc caacatcttt attagcacaa gttgatagtt
     1741 ctgtaggtgg aaaagttgga gttgaccttg agagaggcaa aaacttagtg ggaagctttt
     1801 accaaccaaa ggctgtgttt atcgacccaa atgtattatt atcacttcca gaaaaattct
     1861 atagagatgg aatggcagaa gttataaaat atggatgtat aaaagacaaa acttttttca
     1921 ataaactttt aagtttaaaa aatagagaag aagtaatgca acatatagaa tacattatac
     1981 ataaatgttg ctttattaaa aaaactgtag ttgaagctga tgaaaaagac tttggagata
     2041 gaatgcttct aaactttggc catacattag gtcatgctat tgagaaatac tacaatttta
     2101 cgggttatac ccatggagaa gctgttgcca taggaatgta taagataact ttagaaagtg
     2161 aaaagatagg aattacaaaa aaagggacat cagaacttat aaaatcaatt ttaatgaatt
     2221 ataatttgcc ttatgagatt gaattaagag ataataaatc tatagtagat gctatatctc
     2281 ttgataaaaa aaatctaggt gatacattaa aaataatact tttaaaagat attggagaga
     2341 gtattatata taatactact tctaaatttt ttcaggaggt aagataatgg gaagtctaaa
     2401 aatatatcca agtaaattat ctggagatgt aaaaatacca ccatcaaaaa gtatggcaca
     2461 tagggcagtt atttgttcat ctctaagcaa tggaaaaagt agaatttcta atatagattt
     2521 ttctgatgat ataatagcta ctataagagc aatgacatca ttaggagcta ttatagaaaa
     2581 gaaagaagat attttagaaa tttcgggaat tttttctaaa gaaggtattt taaatagaga
     2641 gaatcagttg aatcaaccta aattgacaat agattgtaat gaatcaggct ctacattgag
     2701 atttttagta cctatatctt tagcatttga tggtgtaaaa aggtttatag gtagaggaaa
     2761 tcttggaaaa agaccacttg atacttatta tgagatattt gacagacaga atataaaata
     2821 tagttacaaa gaaaatcagt tagatttgat tatatcaggt aagcttaaac cagatgaatt
     2881 tagagtaaaa ggaaatataa gttctcagtt tatcacaggt ttactgttta tattgcctac
     2941 gctagagagt gattcaaaga taataattac tactgagcta gaatctaaag gatatttaga
     3001 tttaactctt tcaacgataa aagattttgg ggtagaaatt ataaacaata actataaaga
     3061 atttattata aaaggaaatc aaacgtataa agcgagagat tataaagtag aaggagatta
     3121 ttctcaagga gcattttatt tatcagcaga tgctatagga gaagatatta gcatattaga
     3181 ccttaaagaa gattctcttc aaggggatag tgaagtagtt gaaattttat ctaggatggg
     3241 aatggaaata ttaagagaag gcaacaaaat aaaaggaata acaaatggtt taaatggtac
     3301 tttgatagat gcatctcaat gcccagatat aatacctgta ttatctgtag tagcatcctt
     3361 aagtataggg aggactacaa taattaatgc tggtaggctt agaattaaag aatgtgatag
     3421 acttcatgca ataaatgttg agttaaataa acttggagca aatatagagg agaaagagga
     3481 tagtttgata atcgaaggag taagcaagtt aaatggtgga gtagaggtgt ggagtcacaa
     3541 agaccataga attgctatga cacttgcaat tgcttcttgt agatgtgata aaccaataat
     3601 attaaaagat tttgagtgtg tatcaaaatc ttatccacat ttttttaaag attttaagat
     3661 gttaggaggt cgaattgatg agtggaatat ggggaaataa tttaaaagta tcaatttttg
     3721 gagaatctca tggaaatgct ataggtataa atatagatgg tcttccttcg gggattgaac
     3781 ttgaccttga taatattgat aaagaaatga agagaagagc acctggaaaa aattctatat
     3841 ctacttcaag aaatgaaagt gatataccag aaattctaag tggatatttt aatggaagaa
     3901 ctacaggaac gccattatgt gcaatcataa gaaatagtga tactcgttca aaagattatg
     3961 gagagcttaa aaacttaatg agaccaggac atgcagattt cacaggtaat gtgagatatt
     4021 ctggatttaa tgactataga ggtggaggtc atttttcagg taggataaca gctccattag
     4081 tattttgtgg ggctatatgt aaacaaattt tatcacaaaa aggaatagag ataggagcac
     4141 acataaaaaa aattaaaaat atagaagata tgagttttga ttatgtaaat atttcaaaac
     4201 aacagttatc aaatttgcaa actttggaac tacctttact tgatttatca aaggaagaag
     4261 ccatgaaaaa tacgattata gatgcaaaaa atcaaggaga ttcagttggt ggtataattg
     4321 agtgtgcagt agtaggtatt aatgtagggc ttggaaatcc attttttgac tctgttgaat
     4381 ctactttatc acatttattg ttttctgttc ctgctgtaaa aggtgtagag tttggtttag
     4441 gttttgaact tgcagatatg tatggctctc aaagtaatga tgaaatgtat tatgaaggaa
     4501 atcaagttaa gagcaaaaca aataacaatg gaggaattat aggagggatt actactggaa
     4561 tgccaataat tttcaaagtg gcaattaagc caactccatc aattagcaga caacaaaaca
     4621 cagttaatat aaaagataaa aaggacgata ttttatatat taaaggcaga catgaccctt
     4681 gtatagttca aagggctata cctgtaatag aagcagtaac agccattgga atttttgatt
     4741 tgatgaaagg acgataataa tggaggattt aacgagatat agaaatgaga ttgacaatat
     4801 agataaagag cttattcaat tatttgaaaa gagaatgaat acagttcttg aaattgccag
     4861 acataaaatg aaaaataaca ctactatact tcaaaaagat agagaagaaa aagtactaag
     4921 tagagccgta gataatttag ataataaagc atattcacaa gaaacggtac agttttttaa
     4981 ttctataatg gaaattagta gaggattaca aaaaagattt atagataatg atggtgagca
     5041 gaaaatcgag tttagtttag attcatcaaa taagaatttt gatttgtcaa atgtaaataa
     5101 atataagtct ttaaaagatg aattaaataa aaaaaatatc ctagtaggct ttcctggaaa
     5161 atcaggttca tttacagaag aagcactaaa taaattcttc aacaaaaaaa tatcaaaaaa
     5221 acaatttaaa gaatttgaag atgttttcat agcacttaaa aataaagaaa taaactatgg
     5281 aataatcccc atagaaaatt catctacagg agctatctct gaaacttatg accttttgag
     5341 aaagtacggt ttttatatag ttggagaaga atgtataaaa atagaccaaa atttaatagg
     5401 gataaaagac acaaagcttg aagatataaa agaaatatat tctcatccac aaggtatagg
     5461 acaatgtagt gaatttttaa aacaaaatag tacatggaaa ttgataccct ttaataacac
     5521 agcaacaagt gcagaacttg taagaaaact tcaagataaa acaaaagcag caattgcaag
     5581 caaaaaagct gcaagtattt atggattaga aataataagt ccttgtataa atgatatagc
     5641 aaacaactat acaagatttg tagtaatcag taatcaaata cacattgaag aagaatcaaa
     5701 caaaatgagt gtagtatttt ctgttgaaca tgaagcagga aaactttata aagtacttgg
     5761 atactttgct aaaaataata taaatatgac aaaaatagaa tcaagaccta tgaaaaatgc
     5821 ctcatggaga tatttctttt atatagattt tgagtgttct atatacaatg ctaaagtgta
     5881 cgatttatta gaattgatag aacataatac agcatatttt aaatttatgg gagtatataa
     5941 aaataaaact gaatagataa gataaatttt tatttaattt ataattatta ggaggtgtaa
     6001 gtatgaattt tttcggtcta gtaggtgaaa aactctctca cagtgtttca cctcaaatcc
     6061 acaagagagt attcgagata ttgaatattg aaagtgctta taaaaacttt gaaatttcaa
     6121 aagaagatat atctaagcta gacggtgcta taaaattatt aggaatacaa ggggtaaatg
     6181 ttactgtacc atataaggag cgtattatga aatatcttga ttttatatca ccagaggcaa
     6241 aacgtatagg agcagttaat acaattttac tcagagaaaa tatgttatat ggttacaata
     6301 cagattactt tggtcttgat agtatgttta aaatggctaa tattgatgtt caaggaaaag
     6361 tagcagttat attaggaact ggaggtgctt ctaaagctgc tcttacatat tttattgatt
     6421 ctggtataga aaagctttat gtttcaacta gaaaaaagga tgataaaaaa ttattaaata
     6481 gtaaagctat attaatagat tatgaagaac ttaaacatat aaaaggagat ataatattaa
     6541 atgctacacc agtaggtatg taccctaatg taggaatttc accagtgtca aaatctatta
     6601 tacaaaattt tgatatatta atagatttaa tttacaatcc tggagaaaca gagtttttaa
     6661 gaattggtaa tagtatgggt aaaaaaactt gtgatggatt atatatgctg gtggggcaag
     6721 caataaaatc tcaggaaatt tggcaagata ctaaaataga taatagtatt ttagatgtta
     6781 tatataatga actaaaatta gaatttttgt aagggagatt gttatgataa ataaaacaaa
     6841 agaaaaattg atattaatag gtatgccagg tagtggaaaa actacaattg gtaaactttt
     6901 ggccaaagaa tataattgta gtttctgtga tatggatgat tatataattc aaatatctca
     6961 aaaaagtata gcagagttgt tttcagaagg agaagatatc tttaggaact atgagactca
     7021 agcatgtaga gaactttcta taagtgataa aacagtgata tctacaggtg gaggtgtaat
     7081 aaaaaaggat attaatatgg aaatactaaa agaaacaggt ataataattt ttattgatag
     7141 acctatacaa aagattttgg aagatataaa tattaattca agaccattat taaaaaacgg
     7201 aaaagataga ttgtataatc tttacaatga gagaataaat ctttataaaa aattttcaga
     7261 tatagagatt ttaaatgata aatcattaaa taatgctgta tataatatta caaatgcagt
     7321 cagtgaaaat tttaaatttg actttaaaga aaaataatct agggggaaat aaaaataatg
     7381 aatattgtta ttgtaggact aggagttata ggaggctctt ttgctaaagc attaaaaaaa
     7441 gctggatatg aaaatgtatt tggagtagat gtagatttag aaactttaaa aaaagcagaa
     7501 aaagcaaaaa tcataaaaaa aggatgtact acaggtaaag agttatttaa aaaagctgat
     7561 ttaattatat tatctatata tcctagatta gttgtagatt ttctaaataa taataaaaac
     7621 ttttttaaaa aagggactat aattactgat actacaggaa taaaagaaac acttatcaat
     7681 gatgtgttgc aaattattcc agatgatata gattttatat ttggacatcc aatggcaggt
     7741 agggaaaaaa agggtattga ttttgcaagt gaacaagttt ttaatggcgc aaattatata
     7801 attactccaa ctggcagaaa caacataaaa aatttagagt tagttgaaaa tttaatttta
     7861 gagattggat ttaaaagagt aaaaaagtta acttcacaaa aacatgatga gattatagct
     7921 tttacttctc agttacctca tgttatggca gttgctctta taaatagtga tgaagaaggt
     7981 agagatacgg gtaaatttat tggagatagt tatagagatt taactagaat tgcaaatatg
     8041 aatgaagact tatggagtga acttttttta ggaaatagag ataatttact aaaagttata
     8101 gaaaactttg aatcagaagt aaatttagta aaagaagcta tatttaacaa tgataaaaat
     8161 aaattaatag agtattttaa aaaatcatca ataagaagag aagctttaga aaaataaata
     8221 ttaatattta agctatatat agatgggtat aaatataagc gatagtgtat ttaattgtat
     8281 taataaatat ggattcaata taattaaata tgctattgat atatttgtac ccttaactat
     8341 tgttatcttt tagatgataa tgatatttat ttaaatactc tttattaaca atttataaaa
     8401 cttaattgta aaaaata
//
LOCUS       DAJMZY010000140         8239 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.143, whole genome shotgun sequence.
ACCESSION   DAJMZY010000140 DAJMZY010000000
VERSION     DAJMZY010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8239)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8239)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8239
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.143"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            133..1191
                     /locus_tag="OE968_003409"
     CDS             133..1191
                     /locus_tag="OE968_003409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium channel family protein"
                     /protein_id="HCP7220643.1"
                     /translation="MNCKWISKIDERKKCHREADSSGYCIFHKENKSDEEIQLMMDTL
                     HKEEISEFNGFVFENEFNAEEILTYNYKILDFSESIFKQKANFKKYIFKKNIIFNYTE
                     FRDKVLFNGCVFLENCDFNRTIFSKHYINDRIFEKVKFKGPDLVVNKVENFPRMDGII
                     FSMCTKFVLKNVEYGKSEYEHGKINYRIARNQATKIGEYEMIGFYYYKERIYSSKIMK
                     RSNYPTFSDYLVEKFFDQIARYTTGYGEKPWNILLVIIAIISVFALLYLFVGIESSNS
                     TLVALDINNIGDYSLSEIFKMYMDLWYFSMATFSTVGYGDMVATSLIGKALAGIEVFF
                     GVTIGAIWASVIIKRMIR"
     gene            1295..2479
                     /locus_tag="OE968_003410"
     CDS             1295..2479
                     /locus_tag="OE968_003410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HCP7220644.1"
                     /translation="MKNALKKIISLAMILVFIIPNYSYADDKSVDKYSKTSILIDQET
                     GRVLYSKEPDMKVPLASLSKMMTFLLAIEAIENKEVKETDKVKIDKSIASVKGSSYKL
                     KDGEEVPLIELMRGLMIVSGNDAAIAIAKHVCKTKEAFVDRMNKKAKEIGMSNTHFLN
                     PNGLPIYDLSNPKKPAKENISTAKDIAILGKYMFDHYEKQVTAITDMETYTNSDRSFE
                     KSNTNALLRIIPEVDGIKTGYTGNAGYCLSFSMVVNKNDKNEKKRRVIGVVLGTNHKN
                     KRTSASLALLKYGKENFNMKKVIDKDSFIGKKYIKGTKELEVTLKAKDELYTILKDDE
                     SIKSEVKIKNIEYPVKKGDTMGIIKYYTNSGDLLGSVDIVSNNSIDNVSLKTKLKMKF
                     AN"
     gene            2686..3399
                     /gene="rpsB"
                     /locus_tag="OE968_003411"
     CDS             2686..3399
                     /gene="rpsB"
                     /locus_tag="OE968_003411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HCP7220645.1"
                     /translation="MSVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIYIIDLQ
                     KTVKKVEEAYKFTKEVAETGKPILFVGTKKQAQDAIKDEAERCGMYFVNERWLGGMLT
                     NHKTIKTRINKLRELEKMEEEGVFNVLPKKEVIKLRAEKEKLEKYLGGIKDMPELPGA
                     MFVVDPRKENIAIQEAHRLGIPVVGIVDTNCDPEQLDFAIPGNDDAIRAVKLITGAMA
                     TAVIEGRQGAEEEVAEDQE"
     gene            3478..4389
                     /locus_tag="OE968_003412"
     CDS             3478..4389
                     /locus_tag="OE968_003412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HCP7220646.1"
                     /translation="MANITAQMVKELRESTGAGMMDCKKALQEAEGNMEKAVDLLREK
                     GLSKAAKKAGRVAAEGLVAIEMNDDNTVASMVEVNSETDFVAKNEDFKVFVKDAACMA
                     LATDKEDIASLLGETHKEGITLQEVLNNRVAKIGEKLDFRRFAKVVTNGQVAGYIHGG
                     GKIGVLVEMETEARDAKVLELGKDVAMQVAAMNPKYVSRDEVDAEYIAHETEVLTQQA
                     LNEGKPANIVEKMVKGRLEKELKEVCLLEQTFVKNPDITVKQLVADVAKAVGSDIKVV
                     KVVRFEVGEGIQKREENFAEEVAKQLK"
     gene            4474..5178
                     /locus_tag="OE968_003413"
     CDS             4474..5178
                     /locus_tag="OE968_003413"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HCP7220647.1"
                     /translation="MDKPMYKRVLLKLSGEALAGERGFGINNDVVNDIAIAIKKIQEI
                     GVEVAVVVGGGNFWRGRTSEGMDRTTADYIGMLATVMNAMALQDALENIDVATRVQTA
                     IDMRQIAEPYIRRRAVRHLEKERVVIFGAGTGNPYFTTDTTAALRAAEMEAEVILLAK
                     NVDAVYDKDPKVHADAKKFTELSYMEVIQKELKVMDSTATSLCMDNKIPIKVFELTTE
                     NIIRAVKGENIGTTVK"
     gene            5204..5761
                     /gene="frr"
                     /locus_tag="OE968_003414"
     CDS             5204..5761
                     /gene="frr"
                     /locus_tag="OE968_003414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HCP7220648.1"
                     /translation="MKLEIHKQLEEKMNGTIDALKFEFGTIRAGRANAQMLDKIRVDY
                     YGTPTPINQIGAISVPEPRILMISPWDKSAMHEIEKAIANSDLGLNPSNDGEVIRLSV
                     PALTEERRKELAKKASKAAEEFKVRIRNERRDANEKIKKMEKGGELTEDELKKAQDEV
                     QKMTDKFIKEIDTLLSKKEKDIMEV"
     gene            5764..5967
                     /locus_tag="OE968_003415"
     CDS             5764..5967
                     /locus_tag="OE968_003415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220649.1"
                     /translation="MKKYYNLLGLHVDEVKQYFDEQNINYTVKSIEGKKDKEKLVVPR
                     VIKISEIGDSVELIITYFSDSLV"
     gene            5996..6730
                     /locus_tag="OE968_003416"
     CDS             5996..6730
                     /locus_tag="OE968_003416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HCP7220650.1"
                     /translation="MNNNIIYDIDLNNIPTHIAIIMDGNGRWAKARFLPRTAGHKAGV
                     ETIRDIVKECSKLGVKHLTLYAFSTENWKRPKLEVDTLMNLLSTYLRNEIAELHQNNV
                     KVTAIGDISALPKTCIRELNSAKELTKNNTGVNLNLALNYGSRADIKNALIDIVKNCE
                     SGKIDINNIDEDIIKNYLSTKSIPDPDLVIRTSGEQRLSNFLLWEVAYSEFYFTDIHW
                     PDFKKEELQKAIYVYQRRDRRFGGLK"
     gene            6743..7522
                     /locus_tag="OE968_003417"
     CDS             6743..7522
                     /locus_tag="OE968_003417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HCP7220651.1"
                     /translation="MLTRIIASLALVPLFLFVVYGGIPLYIAETAIVYIALHEFYKAF
                     KIKDVHPIFIIGYLFSIYLAVKNIFNLPLEYTYAVIFILFLASIIYMLMGKNNVIDVS
                     ITFLGVFYIGVFLDFIIITINGFEKGSIYVWLIFVISFMTDIFAYFSGYLLGKHKLIP
                     KVSPKKTIEGAIGGIIGSTLCCILFGYLFGIDLLQLAIIGSIGSVIAQLGDLFASSIK
                     RYVGIKDYGKIIPGHGGILDRFDSVILVAPFVYSAIKFFIR"
BASE COUNT         3414 a          814 c         1525 g         2486 t
ORIGIN      
        1 aatgaagtag attaaaaatt taaaactaag aatctaatat atattttgta actatttaag
       61 tatataaaat aaaataatat ccaaactaat acaaaatagt aataattgtt ttgtactgga
      121 ggatatatat ttatgaattg taaatggata tctaaaatag atgagagaaa aaaatgtcat
      181 agagaagcag attcttctgg atattgtatc tttcataaag aaaataagtc tgatgaagag
      241 atacaattga tgatggatac tcttcataaa gaagagataa gtgaatttaa tggatttgtt
      301 tttgaaaatg aatttaatgc ggaagaaata ttaacttaca attataaaat actggatttt
      361 tctgaatcca tatttaaaca aaaagcaaat tttaaaaaat atatttttaa aaagaatatt
      421 atttttaact atacagaatt tagagataaa gttttattta atggttgtgt attcttagaa
      481 aactgtgatt ttaatagaac catatttagt aaacactata taaatgaccg tatatttgaa
      541 aaagtgaaat ttaaaggacc tgatttggta gttaataaag tagaaaattt tccacgaatg
      601 gatggaataa tttttagcat gtgtacaaaa tttgtgttaa agaatgttga atatggaaaa
      661 agtgagtatg agcatggcaa gataaattat agaatagcta gaaatcaagc aacaaaaatt
      721 ggagaatatg agatgatagg attttactat tataaggaaa gaatttatag tagtaaaata
      781 atgaaacgtt ctaattatcc taccttcagt gattatttag ttgaaaaatt ttttgaccaa
      841 atagcacgtt acacaacagg ttatggagaa aagccatgga atatattatt agttattata
      901 gcaataataa gtgtttttgc tttattatac ttatttgtag gcatagaaag ttcaaatagc
      961 acacttgtag ctttagatat aaataatata ggtgattact cactaagtga gattttcaaa
     1021 atgtatatgg atttatggta ttttagcatg gctacattta gtacagtagg atatggagat
     1081 atggttgcta caagtttgat tgggaaagca ttggcaggta tagaagtatt ttttggagtt
     1141 acaataggag caatttgggc atctgtgatt attaaaagaa tgataaggta atatttgtgt
     1201 aaatatggat aggtattaat tactagatat aaattggact aaatagggaa aatttaaata
     1261 taaatatact taataatcca agaaggtgaa aaatttgaaa aatgcactaa aaaaaattat
     1321 atcattagcc atgattctag tttttataat accaaattat tcatatgcag atgataaatc
     1381 tgtagacaag tattcaaaaa catctatact tatagaccaa gaaacaggta gagttttata
     1441 tagtaaagaa cctgatatga aggtaccatt agctagttta agtaagatga tgactttttt
     1501 acttgcaata gaagctattg aaaataaaga agtaaaagaa actgataagg taaaaataga
     1561 caaatctatt gcatcagtaa aagggtcaag ttataaactt aaagatggtg aagaagtgcc
     1621 acttatagag cttatgagag gtcttatgat tgtatcagga aatgatgcgg caattgctat
     1681 agcaaaacat gtttgtaaaa cgaaagaagc atttgtagat agaatgaata aaaaagcaaa
     1741 agaaatagga atgagtaata cacattttct aaatccaaat ggtcttccaa tatacgattt
     1801 aagcaacccc aaaaaaccag caaaagaaaa tatctctact gcaaaagata tagctattct
     1861 tggaaaatac atgtttgacc attatgaaaa acaagtaaca gctataactg atatggagac
     1921 atatacaaat tcagatagaa gttttgaaaa aagcaataca aatgcattat taagaattat
     1981 accagaagta gatggtataa aaactggata tactggcaat gctggatatt gcttatcatt
     2041 ttctatggtt gtaaataaaa atgataaaaa tgagaaaaaa cgtagagtaa taggggttgt
     2101 attaggtact aaccataaaa ataaaagaac ctctgcttca ttagctctac tgaaatatgg
     2161 aaaagaaaat ttcaatatga aaaaagtaat tgataaagat agctttattg gtaagaaata
     2221 tataaaagga acgaaagagt tagaggttac attaaaagca aaagatgaac tttatacaat
     2281 attaaaagat gatgaaagta taaagtcaga agttaagatt aaaaatatag agtaccctgt
     2341 taaaaaaggt gatactatgg gtattataaa atattatact aattcaggtg acttacttgg
     2401 aagtgtagat atagtaagta ataatagtat agataacgta tcattaaaaa caaaattaaa
     2461 aatgaaattt gcaaattaaa ttcaaaaaat ggtataaaat acacaaaaaa atataaaaat
     2521 agaaaatatg gaaaaaatat tgttatttct tcacctctgt gatatactac tagaggtgaa
     2581 aaaataaaat aaatcacaca cagcattggg atccttaaaa ggtgcctatt acatggtttt
     2641 ttagggagaa gatcaagctg gaggtataaa accaggaggt aagatatgtc agtaatatca
     2701 atgaaacaat tattagaagc aggtgttcac tttggtcacc aaacaagaag atggaaccct
     2761 aaaatggcta agtatatatt cacagagaga aatggaatat atataatcga cttacaaaaa
     2821 acagttaaaa aagttgaaga agcttacaag ttcactaaag aagtagctga aacaggaaag
     2881 ccaatcttat tcgtaggaac taaaaaacaa gctcaagatg cgataaaaga tgaagctgaa
     2941 agatgtggaa tgtactttgt taatgaaaga tggttaggtg gaatgttaac aaaccacaaa
     3001 actataaaaa caagaataaa taaattaaga gaattagaaa aaatggaaga agaaggcgta
     3061 tttaatgttc ttcctaaaaa agaagttata aaattaagag ctgaaaaaga aaaactagaa
     3121 aaatacttag gtggaataaa agacatgcct gaattaccag gtgcaatgtt cgtagttgac
     3181 ccaagaaaag aaaacatagc tattcaagaa gctcatagat taggtatacc agtagttggt
     3241 atagttgata ctaactgtga cccagaacaa ttagactttg ctataccagg aaatgatgac
     3301 gctataagag ccgtaaaatt aataactggt gctatggcaa cagctgtaat tgaaggtaga
     3361 caaggtgctg aggaagaagt agctgaagac caagaataat aatttgacaa ttaaatggta
     3421 agggtcgccc ttaccattta taatatggaa tagaataagt aggaggaaac ttaaaaaatg
     3481 gctaatataa ctgctcaaat ggtaaaagag ttaagagaaa gtacaggcgc aggaatgatg
     3541 gactgcaaga aagctttaca agaagctgaa ggaaacatgg aaaaagcagt agatttatta
     3601 agagaaaaag gattatcaaa agctgctaaa aaagctggta gagttgctgc tgaaggtcta
     3661 gttgcaatag aaatgaatga tgataataca gttgcttcta tggtagaagt taactcagag
     3721 acagatttcg ttgctaaaaa cgaagacttc aaagtgttcg ttaaagatgc tgcttgtatg
     3781 gcattagcta ctgataaaga agatatagct tctttattag gtgaaactca taaagaagga
     3841 ataactttac aagaagtttt aaataataga gttgcaaaaa taggtgagaa attagacttt
     3901 agaagatttg ctaaagttgt aactaatgga caagttgctg gatacattca cggtggtgga
     3961 aaaataggtg ttcttgttga aatggaaaca gaagctagag atgctaaagt tttagaatta
     4021 ggtaaagatg tagctatgca agttgctgct atgaatccta agtatgtttc aagagatgaa
     4081 gtagatgctg aatacatagc acatgaaaca gaagtattaa ctcaacaagc tttaaatgaa
     4141 ggaaaaccag ctaatatagt tgaaaaaatg gttaaaggaa gattagaaaa agaattaaaa
     4201 gaggtttgtt tattagagca aactttcgtt aaaaatccag atataactgt taaacaatta
     4261 gttgctgatg ttgctaaggc agtaggttct gatataaaag ttgttaaagt tgtgagattc
     4321 gaagttggtg aaggtataca aaagagagaa gaaaactttg cagaagaagt tgctaagcaa
     4381 cttaagtaat aaccaaagag agaacacgca ggtgttctct tttttaaaaa atagaaaaaa
     4441 ttggatatga aggattgaaa taggaggttt ctgatggata aaccaatgta caaaagggta
     4501 ttgttaaaat taagtggaga agcattagca ggagaaagag gttttggtat aaataatgat
     4561 gtagttaatg atattgctat tgctataaaa aaaatacaag aaataggtgt tgaagtagct
     4621 gtagtagtag gtggaggaaa cttctggaga ggcagaacca gtgaaggaat ggacagaact
     4681 actgctgact atataggaat gttagctaca gttatgaatg caatggcgct acaggatgca
     4741 ctagaaaata tagatgttgc tacaagagtt caaactgcta tagacatgag acaaattgca
     4801 gaaccatata taagaagaag agcagttaga cacttagaaa aggaaagagt tgttatattt
     4861 ggtgcaggaa caggaaaccc ttactttaca acagatacaa ctgctgcttt acgtgctgct
     4921 gagatggaag cagaagttat attgttagct aaaaatgttg atgcagtata tgacaaggat
     4981 ccaaaagtac atgcagatgc taagaaattt acagaattaa gttacatgga agttatacag
     5041 aaagaattaa aagtaatgga ttctacagct acatctttat gtatggataa taaaattcca
     5101 ataaaggtat ttgagcttac aacagagaat ataataagag cagtaaaagg cgaaaatata
     5161 ggaactactg taaaataatg aagaatgaag gaggagtaaa attatgaaac tggaaataca
     5221 taagcaatta gaagagaaaa tgaatgggac aattgatgct ttaaagtttg aatttggaac
     5281 tataagagca ggaagagcta atgcacaaat gctagacaaa ataagagttg attattatgg
     5341 aactccaact ccaataaatc aaataggtgc tatatctgta ccagaaccaa gaatattaat
     5401 gatatctcct tgggataaat ctgctatgca tgaaatagaa aaagcgatag ctaactcaga
     5461 cttaggatta aatccatcaa atgatggtga ggttataaga ctttctgtac ctgctttaac
     5521 agaagaaaga agaaaagaat tagctaaaaa agctagtaaa gctgcagaag aatttaaagt
     5581 tagaataaga aatgaaagaa gagacgccaa tgagaaaatt aaaaagatgg aaaaaggcgg
     5641 agaattaact gaagatgaat taaaaaaagc acaagatgaa gttcaaaaaa tgactgataa
     5701 atttataaaa gaaatagata cattattatc taaaaaagaa aaggacataa tggaggtata
     5761 atattgaaaa aatattataa ccttttaggt cttcatgtag atgaggtaaa acaatatttt
     5821 gatgagcaaa atataaatta taccgtaaaa tctattgaag gtaaaaagga taaagaaaaa
     5881 cttgtagttc ctagagttat aaaaatatct gagataggtg atagtgtaga actgataatc
     5941 acatactttt ctgactcctt agtttaagga gtcagaacaa tattggaggc aaaatatgaa
     6001 taacaacatt atatatgata tagacttaaa taacatacct actcatattg ctattataat
     6061 ggatggaaat ggaagatggg caaaagctag atttcttcca agaactgcag gacataaggc
     6121 tggagtagaa actataagag atatagtaaa agaatgctca aaattaggtg ttaagcactt
     6181 aacattatat gcattttcaa cagaaaactg gaaaagaccg aaacttgaag ttgacacact
     6241 tatgaactta ttatctacat acttaagaaa tgaaatagct gaacttcacc aaaacaatgt
     6301 aaaagtaact gctataggag atataagtgc tttaccaaaa acttgtataa gagaattaaa
     6361 ctcagctaag gaactgacaa aaaacaatac aggagttaac ttaaatttag cattaaacta
     6421 cggaagtaga gcagatataa aaaatgctct tatagatata gtaaaaaatt gtgaaagtgg
     6481 taaaatagat ataaacaata ttgatgaaga tattataaaa aactatttaa gcacaaagtc
     6541 tataccagat ccagacttgg taataagaac aagtggtgaa caaagattga gtaacttttt
     6601 actttgggaa gttgcttatt ctgagtttta ctttactgat atacattggc ctgattttaa
     6661 aaaagaagaa ctacagaagg ctatatacgt atatcaaaga agggatagaa gatttggagg
     6721 acttaagtaa ggagattatt ttatgcttac aagaattatt gcttcactag ctctggttcc
     6781 attatttcta tttgttgtat atggaggtat tcctctatat atagctgaga cagcaatagt
     6841 ttatattgca ttgcatgagt tttataaggc atttaaaata aaagatgtac atccaatatt
     6901 cattatagga tatttatttt ctatttattt agctgtaaaa aatattttta atttaccatt
     6961 agaatatact tatgcagtaa tttttatttt atttttagca agtataattt atatgttgat
     7021 gggcaaaaac aatgttatag atgtttcgat tacgttttta ggagtttttt atataggagt
     7081 atttttagat tttataatta taactataaa tggatttgaa aaaggtagta tatatgtatg
     7141 gcttatattt gtgatatctt ttatgacaga tatatttgca tattttagtg gttatttact
     7201 tggaaaacat aagctaattc ctaaagttag tcctaaaaag actatagaag gagctattgg
     7261 aggaataata ggaagtacac tttgttgtat tttatttgga tatttatttg gcattgattt
     7321 gcttcaatta gcgataatag gaagtatagg aagtgtaata gctcaattag gagatttatt
     7381 tgcatcttct ataaagagat atgtagggat aaaggattat ggaaagataa tacctggtca
     7441 tgggggtata ttagatagat ttgatagtgt tatattagtt gcaccttttg tatatagtgc
     7501 gattaaattt tttattagat aaagattggt tggatttaaa agagcaatct ataattgcta
     7561 gtaatgaaaa tagctatgta acttttaaat gcagagatat tctgcagtta ttagttacat
     7621 ggctattttc attgttcaaa aatttagaag accttgggga attgtataag aataggtatt
     7681 actttataat agtatactat atttgtagtg agtatatttt ttatactata actatcatta
     7741 aaaaatattt ttttgtttaa taatttcgat atttttagct atattatata tttataatat
     7801 atatgtataa atgtaactaa tttattatcc atttataaat tttattttta aatataatta
     7861 ataagaaata agtaaattat tggtcttatt acacaaaaat agatataatt taagtaatat
     7921 accaaaaaaa aggaatatat ttacataata tgataaaata aattcaaaga gttaaattgt
     7981 aggtaaatag tattttaatt atttattaaa atatagatta tgtatatgcc aaatttaaaa
     8041 agagacataa agacattata caaatatatt attggggtga tattttataa gaaaagaagt
     8101 gatgcagtaa attaattgag caatttaaaa atgatttaat gatagtgttg atgaatgttt
     8161 aaaaagaaat tttagaaaaa cgtatattgc tgtttgtgtt ggaggtgatg aatttgtata
     8221 atttatagga tataaatga
//
LOCUS       DAJMZY010000141         8115 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.144, whole genome shotgun sequence.
ACCESSION   DAJMZY010000141 DAJMZY010000000
VERSION     DAJMZY010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8115)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8115)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8115
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.144"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            435..2669
                     /locus_tag="OE968_003418"
     CDS             435..2669
                     /locus_tag="OE968_003418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HCP7220652.1"
                     /translation="MQNHNYIKMLNKKVEVLSKELDSRNFKLKTLNEIDFFSKIPNRE
                     FMYQHIDDCISKNIHIGIMLLNIDNFKLFNDIYGYLVGENLLITLTQNLLHFIPESKG
                     IVAYLKGEGFLIVLPNVSNKELNNMGATIIESARELKIKLPNEKEIYSNVTFSIGSTI
                     WNGEPNMTTLMLFNQVYSALKKAKSEGKNRYILFDFKDNSFYNKLENDKEFLSEISHV
                     LQTKQIEVFYQPLYNIKNNTIVGCEALARWRHPIKGLLTPDKFIPLFEQFGLITELDL
                     HLFEENCKNIRRWIDNNDVFVPICCNFSRLHFFNPNFPSMLKGITEKYSVSTSNFSIE
                     ITENILIENTNTIIQQLAELRSYGFSVSMDDFGSGYSSFGMLQNLPFDIIKIDRIFLS
                     HNLNDFKNTTILYSIINIARALGMLTVCEGVETEQHVEFIKSINCDIAQGYYYAKPME
                     CKEFEKLLSKENNSEKMFIKYSDIGKSLIEKIFDGFFIMQDMKKLRANVTEDIQWFDF
                     YNKTEITSFPKVIEHFEKHIKGKKFSILYKSITPHNTESDSLLISGEAVLSDEASEHQ
                     KYSNFYFSANCIISENKLLLAKLHLDLIKTAGYINEFESYSIPKMTNTHLDESNILSQ
                     FYSMLPVGIIRYDLFGDMIITYMNEEMFDIIGYTKEQFFGEMGGNLRAIVHPDDLDFV
                     YKKSLDMIDTNKIEPFLYRFIKRDGQIVTVMYTQCNLSAIDGRSIAQGMYVDVNKIKN
                     LTKI"
     gene            2700..3533
                     /locus_tag="OE968_003419"
     CDS             2700..3533
                     /locus_tag="OE968_003419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HCP7220653.1"
                     /translation="MFKEIFLRTFPGFLIIRDSNYRIIFINDNLKNLIKSYMQDNPLG
                     MTNIEIAKKLPDNIAKFFTDSHNIQLDWEKNYPYDKISNWILEFKKDTTSYWNVLEYK
                     VDVDEKTYIITMANDITKLYEENKRNLHYSITDPLTGAYNRKYLNDRFDIFIGDYIVL
                     IDLDNFKMINDYEGHNVGDKILCDFVSLLNKELINSTSIIRLGGDEFIVIFSSDVDKN
                     YVYSQLEALRENFLKVFSKYKYLSFSYGVDTVKRNLKLTIVELDKKMYKNKKKFDKND
                     Y"
     gene            3773..5506
                     /locus_tag="OE968_003420"
     CDS             3773..5506
                     /locus_tag="OE968_003420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HCP7220654.1"
                     /translation="MSILLKKAPKLAKHIITSFYINRDIDEVLKYLCENVTWIGPGEQ
                     EFLTSFNEIKNYFYAGQDEIPSCDINNDIFETVSEDENRCMVLGRYTVRTKENTQMIL
                     EVNQRCTFEIIEDRGKLLVKHMHISNPYGEMQLDEYFPTKIGTQSYDYLQRLLKEKTE
                     VIEMITNNINGGLKGSNDDNTYSFFYVNEGLPKILGYTYDEFMEMSGGSAVGAVYPPD
                     LPKALEDCERCFAKGPTYSSEYRIRKKDGTLMWVLDSGMKSLNSDGIVKINSIITDIT
                     QLKNIESELKLERERYRIALQNITDIMFEYDIENDTLIKYQRVEIDKKIELENFETKN
                     YSKLLESGKIIHLDDIGKLLEVLHGNLRETIEIRQVNSLTKNEWRWIRVQCSVIYDSD
                     HNPIKTIGVLKDITEDKSKLESLINQAQRDPLTQLYNQRVSQNLIEEYLCSSDSKNND
                     ALLVIDIDDFKTVNDTFGHLEGNEVLVAVSKILLHNTHDKDIVARIGGDEFTIFIKSL
                     TKDLIIKITNDILNDASKIKVKDNHKITLSIGIAFTDDSTKLYKDLFSKADKALYLSK
                     ADGKNCYSTYE"
     repeat_region   5838..6456
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=5967..5995
                     /rpt_unit_seq="atttacataccacttagttaatataaaac"
     gene            complement(6986..7090)
                     /locus_tag="OE968_003421"
     CDS             complement(6986..7090)
                     /locus_tag="OE968_003421"
                     /inference="COORDINATES: protein motif:HMM:NF024729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HCP7220655.1"
                     /translation="MDDYIYYYNNFRYQNRLNSMSPFEFRKYLSTERA"
     gene            7715..7960
                     /locus_tag="OE968_003422"
     CDS             7715..7960
                     /locus_tag="OE968_003422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220656.1"
                     /translation="MNQKKIKISIKMVIIGIFAVIIAFVLSRLFVEYIDELLRSNWQY
                     QLFESESSYIVFANCIMFSNILLEIFLIYICRKFRKI"
BASE COUNT         3271 a          965 c         1059 g         2820 t
ORIGIN      
        1 acttaatttt aataactaaa attaattatg caaaattatt aatatggtat taaattatgt
       61 ataaaaagtt aattatgaat aaaataatta tgcctttgaa aaatcattaa acttaaaatt
      121 aattataaaa aaactctacc ttactaacta tacagctcac aatctatcta tttatgaaaa
      181 aatatgatat aattgcattc aaaaaggaaa tctttcaata tactagaatt taagcattaa
      241 ctaattttat ctaatattat tactaaacta aaaaatattt gtatttgtag cattggagca
      301 agtaacttaa tgtatattca ttttaaatac ttatttaaaa tttagcattt aaattattta
      361 caaattaaca tttaaatact tctagcataa atacagttgt cattaaaatt taaagtatct
      421 tatggaggaa taccatgcaa aatcataatt atataaaaat gttaaataaa aaggtagaag
      481 tattatctaa ggaattagat agtagaaatt ttaaattaaa aaccttaaat gaaatagatt
      541 ttttttctaa aataccaaac agagaattta tgtaccaaca tattgatgac tgtatttcga
      601 aaaatataca tataggaatc atgttattaa atatcgataa ctttaaatta tttaatgata
      661 tatatggata cctagtcgga gaaaatttat taattactct aactcaaaac ctattgcact
      721 ttattccaga atcaaaggga atagtcgctt atttaaaagg agaaggtttt ttaattgtac
      781 ttccaaatgt atcaaataaa gagttaaata atatgggtgc aactattata gagagcgccc
      841 gagaattaaa aataaaactt cctaatgaaa aagaaatata ctccaatgtt acatttagta
      901 tcggcagcac tatctggaat ggtgaaccaa acatgactac tttgatgctt ttcaaccaag
      961 tatatagtgc tttaaaaaag gctaaaagtg aaggtaaaaa tagatacatt ctatttgatt
     1021 ttaaagataa tagtttttac aataaattag aaaatgataa ggagttctta tcagaaatat
     1081 cacatgttct acaaactaaa caaattgaag tattttacca accactttat aatataaaaa
     1141 ataatactat agttggatgt gaggcacttg caagatggag acaccctatt aaaggacttc
     1201 ttactccaga taaatttatt cctttatttg aacagtttgg tctgataacg gaattagatt
     1261 tgcatttatt tgaagagaac tgtaaaaata taagaagatg gattgataac aatgatgttt
     1321 ttgttccaat ttgttgtaac ttttctcgtc ttcatttttt taaccctaat tttccaagta
     1381 tgctaaaagg tattactgaa aagtacagcg tctctacatc aaattttagc attgaaataa
     1441 cagaaaatat attaatagaa aatacaaata caattattca acaactagct gaacttcgtt
     1501 cttatggttt ttctgtatca atggacgatt ttggttctgg atattcatct tttggtatgt
     1561 tgcaaaatct accttttgat ataatcaaaa ttgataggat atttttatct cataatttaa
     1621 atgattttaa aaatacaacc attttgtact ctataataaa cattgcaaga gctcttggga
     1681 tgcttacagt atgtgaaggt gttgaaacag aacaacatgt agaatttatt aaaagtataa
     1741 attgtgatat cgcccaaggt tattattatg caaaacccat ggagtgcaaa gaatttgaaa
     1801 aattactatc taaagagaat aattcagaga aaatgtttat aaaatattct gatataggaa
     1861 aatctttaat agagaagata tttgatggat tttttattat gcaagatatg aaaaaactaa
     1921 gagctaatgt cactgaagac attcaatggt ttgattttta caacaaaact gaaattacat
     1981 cttttcctaa agtaatagag cattttgaaa aacatattaa aggtaaaaaa ttttctattc
     2041 tttacaaaag tataacccca cataatactg aatcagattc attattaatt agtggagaag
     2101 ccgttttatc agatgaagct tctgaacatc aaaaatatag caatttctac tttagtgcaa
     2161 attgtataat ttcagaaaat aaattactct tagcaaaatt acatttggat ttaattaaaa
     2221 ctgctggcta tataaatgaa tttgaatcat attcaatacc taaaatgaca aatacacatc
     2281 ttgatgaaag taatatttta tcacaatttt attcaatgtt gcctgtaggt ataattcgct
     2341 acgatttatt tggtgatatg attattactt atatgaatga agaaatgttt gatattatag
     2401 gttatacaaa agaacagttt tttggtgaga tgggcggaaa tttaagagca attgttcatc
     2461 cagatgattt agactttgtt tataaaaaaa gtttggatat gattgacaca aataaaattg
     2521 aaccattttt atatagattc ataaaacgag atggtcaaat tgtcacagtt atgtatacac
     2581 aatgtaacct ttctgcaatt gatggaaggt cgattgccca gggtatgtat gtagatgtaa
     2641 ataaaataaa aaatttaaca aaaatctagt acaaagtatt ttattttgga gaaattaata
     2701 tgtttaaaga aattttttta agaacttttc caggatttct aattataaga gattctaact
     2761 acagaattat atttataaat gataatttaa aaaatttaat taaaagttat atgcaagata
     2821 atccacttgg aatgactaat atagaaatag ctaagaaact ccctgataat attgctaaat
     2881 tttttacgga ttctcacaat attcaattag attgggaaaa aaattatcct tatgataaaa
     2941 tttcaaattg gattttagag tttaaaaaag atactacaag ctattggaat gttttagaat
     3001 ataaagtaga tgttgatgaa aaaacctaca taattactat ggccaatgat ataacaaaac
     3061 tctatgaaga aaataagaga aatcttcact actcaattac tgacccatta actggagcat
     3121 ataatagaaa atatttaaat gatagatttg acatatttat aggagattat attgtactaa
     3181 ttgacttaga taatttcaaa atgataaatg actatgaagg tcataatgta ggagacaaga
     3241 ttttatgtga ttttgtttca cttttaaata aagaattaat aaattctact tctattataa
     3301 gattaggagg agatgaattt attgttatat tctctagtga tgttgacaaa aattatgttt
     3361 attcacaact agaagcctta agagaaaatt ttttaaaagt attctctaag tataagtatc
     3421 tttcatttag ttatggtgtt gatacagtaa aaagaaattt aaaattgaca atagttgaat
     3481 tggataaaaa aatgtataaa aacaagaaaa aatttgataa aaatgattat taatattgtt
     3541 attttaaaat aaattaaaat tatctttctt tttttaaact tgtacattag tttataaata
     3601 tgtatctata caagatattg acattaagta ctgaagcata tattgtttca gttctttttt
     3661 gttaaaatta acttatttaa caaagatatc atagtttaac aaagctttta atttaaatat
     3721 attgatgtat aatataatta aaatataata gcaaaaagaa aggaggaata tcatgagcat
     3781 actcctaaaa aaagcaccca aattagcaaa acatattata acaagttttt atataaatcg
     3841 ggatattgat gaagtattaa aatacctttg tgaaaatgtt acatggatcg gaccaggaga
     3901 acaggaattt ctcacttctt ttaatgaaat aaaaaattat ttttatgcag gtcaagatga
     3961 aattccttct tgtgatataa ataatgatat atttgaaact gtaagtgaag atgagaatag
     4021 atgtatggta ttaggaagat atactgttcg aactaaagaa aatactcaaa tgattttaga
     4081 ggtaaatcaa cgttgtacat ttgagataat tgaggataga ggaaaattat tagtaaagca
     4141 catgcacata tcaaaccctt atggtgaaat gcaacttgat gaatactttc ccactaaaat
     4201 tggaactcaa agttatgatt atttgcaaag attactaaag gaaaaaacag aagttattga
     4261 aatgattaca aataatatca atggtggctt aaaaggtagc aatgatgata atacatactc
     4321 atttttctat gtcaatgaag gattgcccaa aatattagga tacacatatg atgagttcat
     4381 ggaaatgagt ggtggttcag cagtgggtgc tgtatatcca ccagacttac ctaaagcact
     4441 agaagattgt gaacgatgtt ttgcaaaagg acctacatat tcatctgaat atagaatccg
     4501 aaaaaaagat ggaacattaa tgtgggtatt agattctgga atgaaatcat taaatagtga
     4561 tggcatagta aaaattaata gtattattac tgacataacc caactaaaaa acatagaatc
     4621 tgaactaaaa ttagaaagag agcgatatcg tattgctttg caaaatatta cagatatcat
     4681 gtttgagtat gatattgaaa acgataccct tataaaatat caacgtgtag aaattgacaa
     4741 aaaaattgaa ttagaaaatt ttgaaacaaa aaattactcc aaactattag aatctggtaa
     4801 aattattcac cttgatgata ttggaaaact actagaagta cttcatggaa atcttcgtga
     4861 aacaattgag ataagacaag taaattcatt aactaaaaat gaatggagat ggattcgtgt
     4921 tcaatgttca gttatatatg atagtgacca taaccctatc aaaacaatag gcgttttaaa
     4981 agacataact gaagataaat ctaaattaga aagcttaatt aatcaggctc aacgtgaccc
     5041 actaacacaa ttatataatc aaagagtatc acaaaatctt attgaagagt atctatgtag
     5101 ttctgattcc aaaaataatg atgctctatt agttattgat attgatgatt ttaaaactgt
     5161 aaatgatact tttgggcatt tagagggaaa tgaagtttta gttgctgtat caaaaatact
     5221 attacataac acacatgata aagacatagt tgctcgaatt ggtggagatg aatttacaat
     5281 atttataaaa tcattaacaa aggatttaat aataaaaatt actaatgata ttttaaatga
     5341 tgcaagtaaa ataaaagtaa aggacaatca taaaataaca ttaagtattg gtattgcctt
     5401 cactgatgat tcaactaaat tatataaaga tttattttct aaagctgata aagctcttta
     5461 tctatcaaaa gcagatggca aaaattgtta tagtacatac gaataataaa gctatttata
     5521 cgaccaagaa tgaaccttta aatttaattt catagtctaa caatcaaaga gttgaagcta
     5581 atcttatagc tagtcaacta gttcctagaa aaaatttaaa caatatattt attgatactg
     5641 ctcatttttc taaagagcaa atttatataa aaaattaaac ttttatgtac atacagatac
     5701 taatgataaa cagttatcat tagtatcttc tatcttaaaa caaaatgata atttatctat
     5761 ataaaaaagt gctttgttga cagagttcac ttttttatat aggtacagaa tttaagtata
     5821 aatacatgtt ttattctata cattttagtt aatgtaaaat ttcttgattg tactctctaa
     5881 cttttcaaca ttatactatt tatataccac ttagttaata taaacccctt agctggttct
     5941 agtgcttttt ctatgatttt agtcatattt acataccact tagttaatat aaaaccaatt
     6001 tagatgatgt atatgtgcaa aaggaagaaa taatttacat accacttagt taatataaaa
     6061 cgctactaaa cttgatatac atgaccatta taataataaa tttacatacc acttagttaa
     6121 tataaaactt ccataaaaac atcccctttt tattcttctt ccttatattt acataccact
     6181 tagttaatat aaaacagtct ttttttaatg cagagatgca agaagtttta taatttacat
     6241 accacttact taatataaaa ctatcagtat ttaagtaata atttaagtaa tataggattt
     6301 acataccact tagttaatat aaaacggtca ctacaactta tacttccagt ctaacgattt
     6361 gaatttacat accacttagt taatataaaa catattttgg atttattaat ataaacataa
     6421 ttaaaaaatt tacataccac ttagttaata taaaacccca aaataaactg ggcattttca
     6481 atacttacac atatgcaact ctcttaaatt tgcagtgaac catgagtagt gcaaatgata
     6541 aagcttatca tataccctca acaccttata tttcaagcgt taagctctac tttgtaacaa
     6601 atatcgctca ctgcaaaact atttacattt ttattatatc ataaatatat tatttttgaa
     6661 tatctatacc aatttgtggt ataataaaag caagaagaac tacaatctat ttagacgtag
     6721 agtgaagttc aaatactaat gtttattctt tttgaacttg atttttagtt caaaactaaa
     6781 gtcactcctg cctgtgtgaa ctatacccgc tgttttatac agttaaaaca tgtaaaaata
     6841 gttataaagt actagtgtaa ctcattagta ctctttttat tatattcata taattaatat
     6901 ctatatttta aagtttacta tctaaaaaag agcacgtcaa ataaaaccct agatatttaa
     6961 tttttttaga gatacttaaa ataaattatg ctctctctgt acttaaatat ttcctaaatt
     7021 caaatggaga catagaattt aatctatttt gatatctaaa attattatag tagtatatat
     7081 aatcatctat tgctttaact aattattcat atgtatcaaa tttccttaaa tagtacattt
     7141 ctacctttaa aattccccaa aatccttcca taggagcatt gtcaaggcaa cgaccaactc
     7201 ttgtataata tatgtatatc taacaccatt aagaaatata tattttataa tatatatttc
     7261 ttcatttaat gcacttagaa aagcaaagaa aatacagatt agtacacttt ttagagaaaa
     7321 ataaaattaa tacatctaaa atattaaaaa atactttaga taatctaaag acacatctca
     7381 aagtttttaa ctaaattata aaactaatta caaatgctat gtaacgataa taaataaaaa
     7441 atttacttcg cttaagcgac gtgtcgttga aatatttcat gttgccaact ggttcgtaag
     7501 ttgataagaa aagaacacta attatttaga gttcttttct tagctacaag tggattataa
     7561 tacttttaaa tctgtgagaa aatcatatat aataatgata tgaacaagta aagaaaatac
     7621 aaaaatgaca aaattataaa taaaatatta taaaatcata aggtcataat tgttatattg
     7681 tagaaacaaa gtaaagagag agggtggaga ataaatgaat caaaaaaaaa taaagattag
     7741 tattaaaatg gtaattatag gtatatttgc tgtaattatt gcttttgtat tatccagatt
     7801 attcgttgag tatattgatg aattattaag gtctaattgg caatatcagc tatttgaaag
     7861 tgagagttca tatatagtat ttgccaattg tattatgttc tcgaatatat tattagaaat
     7921 atttttaata tatatttgta gaaaatttag aaaaatctaa tatggtcaac gtatttcgaa
     7981 tcgaatactt catgattatt tagtctattg tgctagttaa agtttaattc ccatataaag
     8041 taaattgatt ttagtaaaac aaatcacccc taagggttag tttatggata agtcatccaa
     8101 atattaactc tttaa
//
LOCUS       DAJMZY010000142         7867 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.145, whole genome shotgun sequence.
ACCESSION   DAJMZY010000142 DAJMZY010000000
VERSION     DAJMZY010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7867)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7867)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7867
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.145"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            271..1689
                     /locus_tag="OE968_003423"
     CDS             271..1689
                     /locus_tag="OE968_003423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium/proton antiporter"
                     /protein_id="HCP7220657.1"
                     /translation="MTELMIISGLVLLICITSSKVLYKFGVPILLIFILLGMLFGSDG
                     MVGIYFDNYELTKQLCSIGLIFIMFFGGFGTNWNMAKPVAIPSILMSSLGVIITAGVT
                     GMFCHMVIGTSLLEGLLIGAIAASTDAASVFAVLRSQKLNLKGSLASLLEVESGSNDP
                     IAYMLTLILLTLMNNSGVELIAPMVIKQIAFGLAIGFILAKLSVYILRHSNFEIEGFY
                     TIFITAIAILSYAFSEYLGGNGYLSVYISGIIIGNSRIPLKKSLVHFFDGISWIMQIM
                     LFFMLGLLSFPSKLPNVFGIAMAISIFMIVIARPLATFIVLAKFKFSNKEKLFISWVG
                     LRGAASVVFAIYAVTQGVAIENDIFHIIFFIALLSVGIQGSLIPTVARKLDLVDDNTP
                     VLKTFNDYDGEISSKLIEVNVDEGNKWANKSIIDSNIPDDILIVMIKRKEQVLIPKGS
                     TIIKTGDILVLSGDRIEELIQL"
     gene            1765..2577
                     /locus_tag="OE968_003424"
     CDS             1765..2577
                     /locus_tag="OE968_003424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HCP7220658.1"
                     /translation="MFSIGMFSKINKITTKTLRYYEDIGLLKPEYVDEFTKYRYYTTE
                     QLPKLHQIITLKQMGLSLAEIKKAVENPEEVENILMNKEKEMLDVIKSEEYKIIKLRN
                     YLMNLKGEVNMNDVIIKSLPKVKVASMRKVLKGYDELFNLFPNVMAEEMMKTGCTCAV
                     PDYCFNIYHDGEYRETDMDVEMCQAINDLKEDTDILKFKELDAVENAVCILHNGPYST
                     LGKTYADAFKWIEDNKYKVVGNPRESYIDGIWNKESEEDWLTEVQIPVKRML"
     gene            3000..3617
                     /locus_tag="OE968_003425"
     CDS             3000..3617
                     /locus_tag="OE968_003425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 domain-containing protein"
                     /protein_id="HCP7220659.1"
                     /translation="MEIFAIGHSNYPYDKLINMIKKYDINCVVDIRETPYSKYNIQYN
                     KEAFNESLRNSGFLYIYMGKEFGAKRTNKDVYTQEGYADFEKVAKEDIFLNGIERLKK
                     GCQMGYRIVLLGAMQEPIRCHRSILVGKVLNKEGFDVKYIMHEGNLAYQEDIEESLLD
                     KYFSDRKQLSIDNLLGSALTREEMIQEGYKLANKEIGYRTEKLGK"
     gene            complement(3774..4226)
                     /locus_tag="OE968_003426"
     CDS             complement(3774..4226)
                     /locus_tag="OE968_003426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220660.1"
                     /translation="MVNLNANNLNVNMVYPISSTAPIRFRRYTVSYLENMENIYLTIA
                     TYFDTLGLGTMNIDKVYGQWAWFTDNIYDLNLFVFVGNYPYQIAKNRYDTFVDILPVA
                     ITSIVNGDRIFLISNPCLLNSKITVRFISSHPTLNRTVDYGNIRDFIF"
     gene            4674..6032
                     /locus_tag="OE968_003427"
     CDS             4674..6032
                     /locus_tag="OE968_003427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HCP7220661.1"
                     /translation="MFIRKNVIKLAIPIMIEQTFVMLLGVFNTMMAGHIGEEAVSAVG
                     MVDSINNIFISVFAALSVGATVVVAQQIGKKDGEKVNETIKQALVSGVILSFTITILM
                     WVFRTGVINLFYGSAEELVKSNAKLYIEFTLFTYPFIATQQIANGLLRGCGDVKKPMY
                     VTMFMNIVNVTLGYILIYGIDLNPLGINLQTPSYGITGAAISIAIARIIGCIVIIRAL
                     FKGNEFISMGKIFPFKIDVETQKSIFNIGIPAGVEQLLFNAGKLIVQVFIVTMGTSAI
                     ASNAIGMSIASIINVIGNALALSATTLVGQYIGRGDIKGAKSTLLYLTKFATICLFIV
                     GAIFIPIAPWISSMYTQNASVIDISTQLIRSDCLAMVIWPISFVLSAGLKGAGDTRYT
                     MMTAVIGMWIFRIFTGYVLGVVLEFGVLGIWIGMYTDWLVRGTLYCLRLRGTKWLKHK
                     VA"
     gene            6305..6685
                     /locus_tag="OE968_003428"
     CDS             6305..6685
                     /locus_tag="OE968_003428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HCP7220662.1"
                     /translation="MINKIGKITLYVNNQEDAKLFWTEKLNFVVTYEKEMGPNMKWVE
                     VAPSKNEFTTFVLYDKNLMMRQNKEINVSHPSIILSTRDINGTYEQMANNEVEVGELM
                     EMPYGRMFSFKDQDGNDYLVREDK"
     gene            6810..7010
                     /locus_tag="OE968_003429"
     CDS             6810..7010
                     /locus_tag="OE968_003429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220663.1"
                     /translation="MFKKMAVLKDIATKIGRKKAYELLEMVEGNDAFVAEVKIKKNGI
                     ESKKEEIMLKDNQKIILEYIEG"
     gene            7206..>7867
                     /locus_tag="OE968_003430"
     CDS             7206..>7867
                     /locus_tag="OE968_003430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCP7220664.1"
                     /translation="MLEIKNLSFNVESNNEELGIINDVSLSFERGKLIVITGPNGGGK
                     STIAKLIMGIEKATSGQIILDGEDITNLSITERAKKGIGYAFQQPPRIKGMTVENLLT
                     LAHGKPLSTDVCCQYLTDVGLCSKDYLNREVDNSLSGGEMKRIEIATLFARDLKVSIF
                     DEPEAGIDLWSFGKLNESFKKIHEESNQTIIIISHQERILELADEIIVLQDGSVKSHG
                     TK"
BASE COUNT         3074 a          771 c         1371 g         2651 t
ORIGIN      
        1 aaaattacta taaaaaatga aatatattaa acaatcaact aaaaaatgaa atattaataa
       61 aaaaaaattc aaattataaa tattaaatga atataattaa aacaaatata taaatttaag
      121 tataacactc acattttaat gtattgtgaa atttttgttg aactttatgt accataactt
      181 ataaaattta tgtcatgtta tatttgaata agtaataaaa ttgtagatgt aaattaatct
      241 acaaaattta tatgaaatgg agttgatgct atgacagaat taatgattat aagtgggtta
      301 gtactattga tttgtataac ttctagcaag gtattgtata aatttggagt accaatatta
      361 ttgattttta tcttactagg gatgttattt gggtctgatg ggatggtagg aatctatttt
      421 gataactatg aactgacaaa acaattatgt tctattggac taatatttat aatgtttttt
      481 ggagggtttg gaacaaactg gaatatggct aaacctgttg ctataccttc tatattaatg
      541 tcttcactgg gtgtaataat tacggctggg gttacaggta tgttttgcca catggtaata
      601 ggaactagtt tacttgaagg tttattaatt ggggcaattg cagcttcaac agatgctgca
      661 tctgtgtttg ctgtgttgcg ttctcaaaaa ctaaacttaa agggttcact tgcatcatta
      721 ttagaagttg aaagtggaag taatgaccca atagcgtata tgttgacact aattcttttg
      781 acattgatga ataattctgg ggtagaactt attgcaccaa tggtaataaa acaaatagct
      841 tttgggttag ctataggatt tatactagca aaattatctg tttatatttt aagacattca
      901 aacttcgaga tagaaggatt ttatactata tttataacag ctattgcaat actttcttat
      961 gcatttagcg agtatcttgg aggaaatgga tatttaagtg tttacatttc aggtattatt
     1021 ataggaaata gtaggatacc tcttaaaaaa agtttggttc atttctttga tggaatttca
     1081 tggattatgc aaataatgtt attctttatg ttaggattgt tatctttccc ttctaagtta
     1141 ccaaatgtat ttggtatagc aatggccata tctatattca tgatagttat tgcaagacca
     1201 ttagcaacat ttatagttct agcaaaattt aaattctcaa ataaagaaaa attattcata
     1261 tcgtgggtag gtcttagagg tgcggcttca gtagtttttg caatttatgc tgttactcaa
     1321 ggagtagcca tagagaatga catattccat ataatatttt ttatagcgtt gctttcagta
     1381 ggaatacaag gttcattgat accaactgta gccagaaagt tggatttagt tgatgataat
     1441 acacctgtat taaaaacatt taatgattat gatggagaaa ttagctctaa acttatcgaa
     1501 gtaaatgttg atgagggtaa taaatgggct aataagagta taatagattc taatatacca
     1561 gacgatatat taatagttat gataaaaaga aaggaacagg ttttaatacc taaaggttca
     1621 accattataa aaacagggga tattttggta ttgagtggag atagaattga agaattaata
     1681 caattataat ttattttgta ttgactttaa cctaagggga aagtttaaac ttaaattaat
     1741 caaatctaat gcgcaggtga tgagatgttt tctataggaa tgttttctaa aataaataaa
     1801 ataactacaa agacattaag gtattatgaa gatatagggt tgttaaaacc agaatatgta
     1861 gatgaattta caaaatatag gtattataca acagagcaat tacctaaatt acatcagata
     1921 ataactttaa aacaaatggg tttatcatta gctgagataa aaaaagctgt agaaaatcct
     1981 gaagaagttg aaaatatttt aatgaataaa gaaaaagaaa tgttggatgt aattaaaagt
     2041 gaagaatata aaataattaa actacgtaat taccttatga atttgaaagg agaagtcaat
     2101 atgaatgatg taattattaa gtctttacca aaagttaaag ttgcttctat gagaaaagtg
     2161 ttaaaggggt atgatgaact ttttaatcta tttccaaatg taatggctga agaaatgatg
     2221 aaaacagggt gtacatgtgc agttcctgat tattgtttta atatatatca tgatggtgaa
     2281 tatagagaga ctgatatgga tgttgaaatg tgtcaagcta taaatgattt aaaggaagat
     2341 acggatatat taaaatttaa agaattagat gcagttgaaa atgcagtttg tatattacac
     2401 aatggtccat attcaacatt aggaaaaact tacgcagatg catttaaatg gatagaggac
     2461 aataaatata aagtggttgg aaatcctaga gaatcttata tagatggtat atggaataaa
     2521 gagagtgaag aagactggtt gacagaagtt cagataccag tgaaacgcat gttataatat
     2581 gtctacaaag tataaataag aataaaaaag gtggtgtctc aaagtaaaca ttttagttta
     2641 tgagacactc tttttcatat gaaatcaagt atatttttat aattacgatt atgaaaaaag
     2701 gcttatctat atttttagac agcctcttat ttttttatta taatagtttt ctaaagatgc
     2761 tctatttata aatttttatt aaagacttta taaataattg tatttaatat acaaaatata
     2821 tataaatatt gatgttttat atataaagtt gtatattttt ttaaggatat aaagtaaaaa
     2881 aatatacaat atcaagaaaa aaagatattg ggtatttaaa gtaatacttt atttaatttt
     2941 aagtaaatcg ggtatctaca tatatagata ctaatttcaa agaataggag ggtgtttata
     3001 tggaaatatt cgcaatagga cattcaaatt atccatatga taagcttatt aatatgataa
     3061 aaaaatatga cataaattgt gtagttgaca ttagagaaac tccatattct aaatataata
     3121 ttcaatacaa taaagaggca tttaacgaat ctcttagaaa ttccggattt ttatatatat
     3181 acatgggaaa agaatttgga gctaaaagaa ctaataaaga tgtatatacg caagaaggtt
     3241 atgcagattt tgagaaagta gcaaaagaag atattttttt aaacggaata gaaagattaa
     3301 aaaagggttg tcaaatgggt tataggatag ttttattagg agctatgcaa gaacctataa
     3361 gatgtcatag aagtatcttg gtgggaaaag tattaaataa agaaggtttt gatgtaaaat
     3421 atataatgca tgaaggaaat ttggcatatc aggaagatat agaggaatca ttactggata
     3481 agtattttag tgatagaaag caactgagta ttgacaattt attagggagt gcattaacga
     3541 gagaagaaat gatacaagaa ggttataagc tagctaataa agaaatagga tatagaactg
     3601 agaaactagg taaataaaaa tatacaagta gataaaatac agtacttatc ttaagtaaaa
     3661 taatattatg aatttataat agctaggcat gatgtgccaa ttaaaaatat tctagttatt
     3721 taataatatc attaaattta gggtattttt taatagcaca tcatgttgca gttttaaaaa
     3781 ataaaatctc taatattgcc ataatcaact gttctattaa gagtaggatg actagatata
     3841 aatctaactg taatttttga atttaacaaa caaggatttg aaattaaaaa tattctatct
     3901 ccattgacaa tagaagtaat agctactggc aaaatatcta caaatgtatc atatctgttt
     3961 ttagcaattt gataaggata atttcctaca aaaacaaata gatttaaatc atatatatta
     4021 tcagtaaacc aagcccattg accataaact ttgtcgatat tcattgtgcc taaaccaagt
     4081 gtatcaaagt atgttgctat agttaaataa atattttcca tgttttctaa atatgaaaca
     4141 gtatatcttc tgaaacgtat gggtgctgtg gaagaaatag gataaaccat atttacattt
     4201 agattatttg catttaaatt aaccaaagta tcacatccta aaattagtct ataaaataca
     4261 atatttaaat ggatgcgatt ttgttacatc taaagtgtaa tattttatat attgaaaaag
     4321 tggtaaaagt ttggatgatt aaataatatt ataaaaaata tataaaatgt acttattgtt
     4381 attgctacac gatagtgata caatattaac gaaatatagc tacttttaat aataacggaa
     4441 aatatttata ttaaattaat aaatatttta aatgtggtat ccataaaaaa taataaacat
     4501 aagataatta taaagatata ctgtgttcaa atgatattaa acaagattta tattatttga
     4561 aagcagtata ttataatgcg aacaatacaa ttctaaactt tgcattgtca atttacagtt
     4621 cgataaacta attaaaaatt aaatttatat aaagagggaa aagaggaata gggatgttta
     4681 taaggaaaaa tgttataaag ttagcaattc ctataatgat agagcagacg tttgtcatgc
     4741 ttttaggagt atttaataca atgatggcag gtcatattgg ggaagaagct gtatctgcag
     4801 ttggaatggt tgattcaata aacaatatat ttatatctgt atttgctgca ctatctgttg
     4861 gagctactgt tgttgtagct caacaaatag gaaaaaaaga tggtgaaaag gtgaatgaaa
     4921 ctattaagca ggctctagtg tctggagtaa tattatcctt tacaataaca atattgatgt
     4981 gggtttttag aactggtgta attaatttat tttatggttc cgcagaagaa ttggtaaaat
     5041 caaatgcaaa attatacata gagtttacat tatttacgta tccatttatt gcgacacaac
     5101 aaatagcaaa tggtctttta agagggtgtg gagatgtaaa gaaacctatg tatgtgacta
     5161 tgtttatgaa tatagtaaat gtaacattag gatatatact tatatatggt attgatttaa
     5221 atcctctagg aataaatttg caaacaccat cctatggcat aacaggtgca gctatatcta
     5281 ttgctatagc tagaataatt ggatgtatag taattataag agctttattt aaaggaaacg
     5341 aatttatatc tatgggtaaa atatttccat ttaagattga tgttgaaact caaaagtcta
     5401 tatttaatat aggaatacca gctggagttg aacaactact ttttaatgca ggtaaattga
     5461 ttgttcaagt atttatagtt actatgggaa catcagcaat tgcatccaat gcaataggaa
     5521 tgtcaattgc atccataata aatgtaattg ggaatgcttt agctttgtct gctacaacct
     5581 tggtgggaca gtatatagga cgtggagata ttaaaggagc taagagtact ttattatatt
     5641 taactaaatt tgcaacaatt tgtttattta tagtaggagc tatatttata ccaattgcac
     5701 cttggatttc aagtatgtat actcaaaatg ctagtgtaat tgacatctca acacaattaa
     5761 ttcgaagtga ttgtttagct atggtaatat ggcctatatc ctttgtatta tcagcagggc
     5821 taaagggagc cggtgatact agatatacaa tgatgactgc agtaataggt atgtggattt
     5881 ttagaatttt tacaggttac gtattggggg ttgtattaga atttggagtg ttaggaattt
     5941 ggataggtat gtatactgat tggcttgtta gagggacttt atattgttta agattaagag
     6001 gaacaaagtg gctaaaacac aaagttgcat agaatatatg aaatcacttt tagatggata
     6061 actctattta gaagtgattt tttatgtagt tattatcata attataagta tgatatataa
     6121 ggtgattaaa ttacataaat aaagcctata atagtatgga tactataaat tatatattga
     6181 gcagaattac ataatttggc gataaatatt agaaatatat atctatagaa aataatatat
     6241 atgggtatat tattaaatat aaaaaatatt aggtatttat ttaataataa aggtgggtat
     6301 tgttatgata aataaaatag gaaaaataac tctctatgta aataatcaag aggatgcaaa
     6361 gttgttttgg acagaaaaat tgaactttgt agtaacttat gaaaaggaaa tgggtccaaa
     6421 tatgaaatgg gtggaagtag caccaagtaa aaatgaattt acaacatttg tgttgtatga
     6481 taaaaatcta atgatgagac aaaacaaaga gataaatgta tctcatccat caataatttt
     6541 aagtacaaga gatattaatg gaacttatga acaaatggca aataacgagg ttgaggttgg
     6601 ggaattaatg gagatgccat atggaaggat gttttctttt aaagaccaag atggaaatga
     6661 ttatttggtc agagaggata aataatttta caaagtatta aatttactca atatctgata
     6721 taattagaga caataattat tataaactag tctaggatta gaattatata attaaaaatt
     6781 aagtgtaaat tttgagtaga ggtgataaaa tgtttaagaa aatggcagta ctaaaagata
     6841 tagcaactaa aataggtcgt aaaaaagctt atgaactatt agaaatggtt gaaggtaatg
     6901 atgcctttgt agctgaggtg aagataaaaa agaatggaat agaatctaaa aaagaagaaa
     6961 ttatgttaaa agataatcaa aaaataatat tagagtatat agaaggctaa tttttaaata
     7021 catataagtt gatatactaa atttctgaga tgagtttaca taaaactcat cttttttact
     7081 tttcaataac tttgttttat tatttaatat acattttatc tgcttagagt tgctgatata
     7141 taaaaattac tgatataata aaagaatgga tattaatgta atattttata gaaaagaggg
     7201 gtattatgct tgaaataaaa aatctttcct ttaatgttga gtctaacaat gaggaactag
     7261 gaataataaa tgatgttagc ctttcatttg agaggggaaa acttattgtt atcacagggc
     7321 caaatggtgg aggaaaatct acaattgcta agcttattat gggaattgaa aaagctacga
     7381 gtggtcagat aattttagat ggagaagata taacaaatct tagtattaca gaaagagcaa
     7441 aaaaaggaat aggatatgca tttcaacaac caccaagaat aaaaggtatg acagttgaaa
     7501 atttacttac acttgctcat ggaaaaccat tgtctactga tgtatgttgc caatatctta
     7561 cagatgttgg attgtgttca aaagactatt taaatcgtga agttgataac tctctttctg
     7621 gaggggaaat gaaaagaatt gagatagcaa ctctttttgc tagagattta aaggtttcta
     7681 tatttgatga acctgaagca gggatagacc tttggagctt tgggaaactc aatgaaagtt
     7741 ttaagaaaat acatgaagag tctaaccaga ctataatcat aatttctcac caagaaagaa
     7801 tattagagtt agctgatgaa ataattgttc tacaagatgg ttcagtaaaa agccatggaa
     7861 caaaaga
//
LOCUS       DAJMZY010000143         7859 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.146, whole genome shotgun sequence.
ACCESSION   DAJMZY010000143 DAJMZY010000000
VERSION     DAJMZY010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7859)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7859)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7859
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.146"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            complement(73..216)
                     /locus_tag="OE968_003431"
     CDS             complement(73..216)
                     /locus_tag="OE968_003431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220665.1"
                     /translation="MSEFLLGVLASLTASFITYIISRKVKSHSGRSDFELDVKIKFNK
                     KRH"
     gene            476..664
                     /locus_tag="OE968_003432"
     CDS             476..664
                     /locus_tag="OE968_003432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220666.1"
                     /translation="MTKTILCDYCNKGINKDDNKYITFHKKSHMKTNICINCALNLID
                     KDKLNENIINNQHDYSKK"
     gene            1366..1887
                     /locus_tag="OE968_003433"
     CDS             1366..1887
                     /locus_tag="OE968_003433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HCP7220667.1"
                     /translation="MDFKIRELINDITQDIIQTYKIQIPIVNINQVVDALGGKVIEDS
                     SLSGYSDGFIRKVDDSFEIVVSPYQPDTRKNFTIAHELGHLFLHMGYGIDDELWNSQD
                     GNQYFRSGNTNKEYQSNEFAAALLMPKHEYKRIMDENTVGNKVDTSKIAEYFNVSSYA
                     ASNRGKWLGYLQW"
     gene            1863..3449
                     /locus_tag="OE968_003434"
     CDS             1863..3449
                     /locus_tag="OE968_003434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220668.1"
                     /translation="MVRIFTMVDDKEYKTQNVNNVHNSAKNENAFNLKKYKEKLQENI
                     NTDIYEKEKEPNHPEVILFFSFDIANSSLYKNINYSGWAKVLSHIIRKLQYRVYENLK
                     AQLWRVLGDEVIFIIVLKNYDEIYKYIDIIFDILTSTAKDIKSGNIFSTLEGFSESEK
                     YLMKLQNIISLKGAAWIAIVSRNPNFNALENNEQYENISAMYDLSNNYKIFEFLGNDI
                     DAGFRISKQTCPERLVLSFELAYILSRKTDILSKLHIITYKKLKGIWKDKLYPIIWYH
                     NKGKNNDIEFDDSFSFDEIEENELVREYFFNKKGESKLLIDSFMFNSVDKALDKILID
                     RNLSDKIEKIGDVISKTNPSYDKNTIDKDYIKVDLMELHCVAVCYNKSTSKILIAKRS
                     DNRNNNASKWEFGCAKASLETSIINTIKDEYEKDFNINIEPITDCTRKDDCQPIPLAI
                     YQVKKSDGLHKGIITLAEIINDYDISKFEPTSKHNELAWIGEDELEDFNENTVPDFKE
                     TLKLAFKKLNENQLQESTNM"
     gene            complement(3513..4031)
                     /locus_tag="OE968_003435"
     CDS             complement(3513..4031)
                     /locus_tag="OE968_003435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220669.1"
                     /translation="MDKKIDIAKFIVNRIDYYIEKSDNKASFLLLLNSAIIGFLFSGK
                     EKIMNHLSISNIRCLEMLFYIVILCIFVISIYFSIMVLKPRNSKIENEYKSIFYYKEI
                     ASLNNEQYKEAFENAFKDEENLINDALVQIKELSLICDKKMYNVKKSVEAFILGGIIL
                     FIYILVVVFNAI"
     gene            complement(4197..4559)
                     /locus_tag="OE968_003436"
     CDS             complement(4197..4559)
                     /locus_tag="OE968_003436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220670.1"
                     /translation="MEDLCMDALVYERFVRAAFSIKLNNLINRSEDLGGLAEADIFRA
                     ANNLHELNEIKIGTGYAIAIFNNEILESCNVSDNDSNRMIELFDRSLIATSREEILDI
                     IREYETYRGRYLTFNWKR"
     gene            complement(4640..5479)
                     /locus_tag="OE968_003437"
     CDS             complement(4640..5479)
                     /locus_tag="OE968_003437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HCP7220671.1"
                     /translation="MKICITVGHSILKSGACTSADGVVNEYQYNKSLAPVLADRFKKE
                     GHKADVIICPEKQFKTKDEEKTYKIPRVNSGGYDLLIELHLNSSGVGAFGTELFYYSE
                     KGKEYAQRVVDKLSKPFIRKKGDKEVGNRGAKLDKSLYILNSSKPTAILIESFFCDNK
                     EDYEKAKKLGHEGIAKLIVEGVLNKNINNEGVKQMYKHTIVYDGEVDKILANVLSWGY
                     SPSKVLVCDIKDYVPGQTENLYVVGGGACEKISSITKEKFIMIKGNDRFDTLYKALDF
                     INR"
     gene            complement(5479..5970)
                     /locus_tag="OE968_003438"
     CDS             complement(5479..5970)
                     /locus_tag="OE968_003438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HCP7220672.1"
                     /translation="MHLKDLDNSRSFLIQKLGGNMNLTIVFLATNIFIKLVILAIAFD
                     TLLGCLRAIKTHQFNSSFGINGGIRKVAMIACIFFLAVVDILTKFNFLFMLPQDWVDF
                     LRLNHLGISEFFSILFILYESVSILKNMYLCGLPVPKKLKDRIGNLLDTMTDELNVKG
                     GSK"
     gene            complement(5978..6196)
                     /locus_tag="OE968_003439"
     CDS             complement(5978..6196)
                     /locus_tag="OE968_003439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220673.1"
                     /translation="MKKIIVICILVLMLIIPTMGEIFIMVENIKLEGLEQNPTSCYIS
                     NPGIMGEAKCDAAYFIIAADFVNNLKVK"
     gene            complement(6296..6478)
                     /locus_tag="OE968_003440"
     CDS             complement(6296..6478)
                     /locus_tag="OE968_003440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015981517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220674.1"
                     /translation="MNINNVVVRILAERILNKGLNPLKNREFELDDVTNTDYRTAVED
                     YIIKQSGVVEGAEPTK"
     gene            complement(6478..6690)
                     /locus_tag="OE968_003441"
     CDS             complement(6478..6690)
                     /locus_tag="OE968_003441"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220675.1"
                     /translation="MKKQVYYNSLDEKEKIIDENSNLYIIEIYETLNENYLVLSSSPA
                     EDKELSYEELENELLIITNELQGGLL"
     gene            complement(6700..7338)
                     /locus_tag="OE968_003442"
     CDS             complement(6700..7338)
                     /locus_tag="OE968_003442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220676.1"
                     /translation="MTTKLTDNASLEELMTTLENVQADFQTGKNNISSALGSPFIGTD
                     KFGTTKTKIETLKNVLVETINSKNVSATSSETFTNLIEKVNWVFQSIEIFSLKNRIQA
                     TIVNTPSIVYNEVSSIKGTLRFTGELQSSKMRADYATAKIEILCGNRKEYFYVTDNTP
                     GASSSLVRFTKDIIVEKGMDIKVQILLTSVGAGNLDGSYAARAEIEELKILR"
     gene            complement(7520..7859)
                     /locus_tag="OE968_003443"
                     /pseudo
     CDS             complement(7520..7859)
                     /locus_tag="OE968_003443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984856.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
BASE COUNT         2843 a         1165 c          878 g         2973 t
ORIGIN      
        1 gtaaattcgt atcaaaaaca aaaaaagaaa ctacaatcta ttagcctaga gtgaagtttc
       61 attaactaaa tattaatgtc gttttttatt aaacttgatt tttacatcaa gctcaaagtc
      121 actcctgcca gagtggcttt ttacttttct ggaaataata tatgtaataa agctagctgt
      181 taaactagct aacactccta gtaaaaattc gctcatttct ccacctcctt ccttttaagg
      241 gatggaatgt agaaaatgaa gctccactct tagattgtag ttccacaaga ttattcttgc
      301 attttaatta taacataatt ttacaattat caaatatcta ttcttcatat tttttattta
      361 tacaatatat tctatattgc aataaaaaac attgttttaa atatatatat acataggtat
      421 atactaaata tgttaaactt aattatagaa aatataaaat gaaaggaata aaaatatgac
      481 taagactata ttatgtgatt actgtaataa aggaataaat aaagatgata ataagtatat
      541 tacttttcat aagaaaagtc atatgaaaac taacatttgt attaattgtg cattaaattt
      601 gatagataaa gataaattaa atgaaaatat tataaataat caacatgatt attcaaagaa
      661 atgaaaaagc actctccata atgaagaatg ctctatataa taatgtttga cttagtaaag
      721 atgtgttggg gttacatatt tactttttta ttatatcata taactttgtg tatgaaaaag
      781 aatttaaatc aattttaagg tgtgttgagt aatgttcttg atagtttata tgttgatgaa
      841 tttcaaaaaa ataagcactc ttataaaaag agtacttttg gtatatattc aagcatttat
      901 ctaatacaat tatagcatgt attatgtttt agtatgataa ttttcgttcg ttttattatt
      961 acaacttcta ctatagtttt catactttaa catcaactaa atgaatttaa ttaagattac
     1021 tagttaatcg ttttttggtt ctttcatatt ctgaaatcta aaattttatt atttgtttat
     1081 tgttattatt taacacatgt tggtatttca acgatttatc ttattgttaa tattcttatt
     1141 gcttccaaag tatatctaat tatttttaag ataatttact aatttttatt ttttcaaaca
     1201 tacattcgac aaaaaacagt ttttatatgg tataattata ttgtataata caaaaggtta
     1261 atgaaaataa ttaatattaa atgtaccaaa aaaaatagtt tttgatataa tgaatattat
     1321 aataaataat tatttaaata aaatattata taaggatgtg attttatgga tttcaaaatc
     1381 agagagctaa ttaatgatat aacccaagat attatccaaa catacaaaat ccaaattcca
     1441 atagtaaata taaatcaagt tgttgatgct ttaggaggca aggtaataga agatagttct
     1501 ttaagtggat actctgatgg atttattaga aaagttgatg attcatttga aatagtggta
     1561 tctccttatc aaccagatac cagaaagaat tttaccattg ctcatgaact tggacattta
     1621 tttttacaca tgggttatgg cattgatgat gaactatgga atagtcaaga tggaaatcag
     1681 tattttagaa gtggcaatac caataaggag tatcaatcca atgaatttgc agcagccttg
     1741 ttgatgccta aacatgaata taaaagaatt atggatgaaa acacagtagg taataaggtc
     1801 gacacttcaa aaattgcaga atactttaat gtttcctctt atgcagcatc taatagaggg
     1861 aaatggttag gatatttaca atggtagatg ataaagaata taaaactcaa aatgtaaata
     1921 atgttcataa ttcagctaaa aacgaaaacg cttttaatct taaaaagtat aaggaaaaac
     1981 ttcaagaaaa tattaatact gatatttatg aaaaagaaaa agaacctaat catccagaag
     2041 tgattttgtt cttttctttt gatatagcta attcatcatt atataaaaat ataaattata
     2101 gcggatgggc taaggtatta tcacatataa ttcgtaagtt acaatataga gtttatgaaa
     2161 accttaaagc acaactttgg agagttcttg gtgatgaggt aattttcatt atcgtactaa
     2221 aaaattatga tgaaatttat aaatacatag atataatctt tgatatttta acaagcactg
     2281 ctaaagatat aaaaagtggt aatatattct ctacactaga aggattttct gaatctgaaa
     2341 aatacttaat gaaacttcaa aatattattt cattaaaagg agcggcctgg attgctatag
     2401 tatcaagaaa tcctaatttt aatgctttag aaaataatga acaatatgaa aatatttctg
     2461 ctatgtacga tttatccaat aattataaaa tatttgagtt cttaggaaat gatattgatg
     2521 ctggtttcag aatatcaaag caaacatgcc cagaaagact tgttcttagt tttgaactag
     2581 cttatatatt atcaagaaaa actgatattt tatctaaatt acatataatt acatataaaa
     2641 aattaaaggg tatctggaaa gataaactat accctatcat ttggtatcat aataaaggaa
     2701 aaaataatga tatagaattt gatgatagtt tttcttttga tgaaatagaa gaaaatgaat
     2761 tggttcgaga atattttttt aataaaaaag gagaaagtaa attactaatt gattctttta
     2821 tgtttaattc tgtagacaag gctttggata aaatacttat agacagaaac cttagtgata
     2881 agattgaaaa aataggtgac gtaatttcta aaacaaaccc cagttatgat aaaaatacaa
     2941 tagataaaga ctatataaaa gtagatttaa tggaattaca ctgtgttgcg gtttgttata
     3001 ataaatcaac ttcaaaaata ttaattgcga aaagaagtga taatagaaat aataatgcga
     3061 gtaaatggga atttggttgt gctaaggcaa gtctagaaac ttcaattata aatactatta
     3121 aagatgaata tgaaaaagat tttaatataa acattgaacc tattactgat tgcacaagaa
     3181 aagatgattg ccaacctata cctctagcaa tttatcaagt taaaaaaagt gatggtttac
     3241 acaaaggcat tataactctc gcagaaataa taaatgatta tgatatttct aaatttgaac
     3301 ccacatcaaa acataatgaa cttgcatgga taggagagga tgaacttgaa gattttaatg
     3361 aaaacacagt acctgatttt aaagaaactt taaaactagc atttaaaaaa ttaaatgaaa
     3421 atcaattaca agaatctaca aatatgtaaa tagtattctt ctatgatttg attctatctt
     3481 catagaggaa tactaaccaa ataaaacatt ttctaaatag cattaaaaac tactacaagt
     3541 atatatataa acaatataat accacctaaa ataaaagctt ctactgactt ttttacatta
     3601 tacattttct tatcacagat taaagataat tcttttattt gaacaagtgc atcattaatc
     3661 aagttttctt cgtctttaaa tgcattttca aatgcttctt tgtactgttc attatttaaa
     3721 gatgctatct ctttataata aaaaatagat ttatattcat tttctatttt agaattcctt
     3781 ggctttaaaa ccataatcga aaaataaatt gaaataacaa atatacataa tataacaatg
     3841 taaaatagca tctctaaaca tctgatatta cttatactta agtgattcat tattttttcc
     3901 ttccctgaaa ataaaaaacc tataattgcg ctatttaata atagtaaaaa actagcttta
     3961 ttatctgatt tttcaatata gtaatcaatt ctatttacta taaacttcgc tatgtctatt
     4021 tttttatcca tgattttact acctcatttc attaaatttt atattgattc aaaattttat
     4081 tttctactta ttatcattga ataaattatt atttggaaat aatcttattg aaataataaa
     4141 aatatgtgaa agaaagtaat aactaactat aattactact tcctaactta aacattctat
     4201 ctcttccaat taaaagtaag atatcgtcct ctataagttt catattctct tataatatcc
     4261 aatatttcct ccctagaagt tgcaattaaa cttctatcaa atagttcaat cattctattg
     4321 ctatcattat cagaaacatt acaagactct aatatctcat tattaaatat tgcaatagca
     4381 tacccagtac ctatttttat ctcatttaat tcatgtaaat tatttgctgc tctaaagata
     4441 tcagcttcag ccaatccacc taaatcttcg cttctattaa tcaagttatt aagtttaata
     4501 ctaaaagctg ctcttacaaa tctctcataa accaatgcat ccatacataa atcctccatt
     4561 atcacaataa tatatttaca ttatattaca ataatagagt tatcacaaca aacaaccact
     4621 tctagttgat aacttttatc tatctattaa taaaatccaa tgctttataa agtgtatcaa
     4681 atctatcatt accttttatc ataataaatt tttctttagt aatagaactt atcttttcac
     4741 atgcgccacc tcctacaaca tataaatttt ccgtctgacc tggtacgtaa tcttttatat
     4801 cacaaactaa aactttgctt ggactatagc cccaactaag cacattcgca agtatcttat
     4861 caacttctcc atcataaaca attgtatgtt tgtacatctg tttaactccc tcattattta
     4921 tatttttatt taatacacct tctacaatta acttagcaat accttcatga cctagtttct
     4981 tagctttctc ataatcttct ttattatcac agaagaaact ttcaattagt attgcagtag
     5041 gtttagaact atttaaaata tataaacttt tatctaattt agcacctcta ttacctactt
     5101 ctttatctcc tttttttctt atgaaaggtt tagacagttt atctaccacc ctctgcgcat
     5161 attccttccc tttttcacta tagtaaaata attctgttcc aaaagctcct acaccacttg
     5221 aatttaaatg caactctata agtaagtcat atcctccact attaactcta ggtattttat
     5281 aagtcttttc ctcgtcctta gttttgaact gcttttctgg gcatattatt acatctgcct
     5341 tatgaccttc ttttttaaat ctatctgcta acactggggc aagagattta ttgtattgat
     5401 actcgttaac tactccatca gcagaagtac atgctccgct ttttaaaata ctgtgtccta
     5461 ctgttataca tattttcatt atttactacc tcctttaaca tttaattcat ctgtcatagt
     5521 atctaataag ttacctattc tatcttttaa ttttttaggc actggtaacc cacacaaata
     5581 catgtttttt aatatactta cactttcata tagaataaat aaaatagaga aaaattcaga
     5641 tattccaaga tgatttagtc gtaagaaatc aacccaatct tgtggtaaca taaataaaaa
     5701 gttaaacttt gtaagaatgt caactactgc tagaaaaaat atacatgcta tcattgcgac
     5761 ttttcttatt ccaccattta ttccaaaact tgagttaaac tgatgtgttt ttattgctct
     5821 taagcaacct aacagtgtat caaatgctat tgctaatatt actaatttta taaatatatt
     5881 tgttgctaaa aaaactattg ttaaattcat atttcctcct aatttttgta ttaaaaagga
     5941 cctagaatta tctaagtcct ttaaatgtat taatttatta ttttaccttt aaattgttaa
     6001 cgaaatctgc agctataata aagtatgctg catcacattt tgcttctccc ataatccctg
     6061 gattagaaat gtaacaactt gttgggtttt gttctagccc ctctagcttt atattttcta
     6121 ccattataaa tatctccccc atagtaggta taattaacat tagaactaga atgcaaatta
     6181 caattatttt cttcattttt caatctcctt ttaatagaat ttttttatta tagataagaa
     6241 taaaaaatat ataactaaaa aaggaaatta tttttaattt atataaaaaa agaacctact
     6301 ttgttggttc tgctccttct actactccac tctgtttaat tatataatcc tctactgctg
     6361 tcctatagtc tgtgttagtt acatcatcta actcaaattc tcgatttttt aaaggattta
     6421 accctttatt taatattctc tctgctaata ttcttactac aacattgttt atattcatta
     6481 caacaatcct ccctgtaatt cattagttat aattaataat tcattttcta attcttcata
     6541 actaagttct ttgtcttctg ctggactact tgataatact aaataatttt catttaaagt
     6601 ttcatatatt tctataatat ataaattaga gttttcatca attatttttt ctttttcatc
     6661 taaagaatta taatatactt gttttttcat aatttattcc taccttaata tttttaattc
     6721 ttctatttct gcacgagctg catatgaacc atctaaattt cctgctccta cagatgttaa
     6781 taatatttgt acttttatat ccatgccctt ctcaacaata atatcttttg taaatcttac
     6841 aagagaagaa gatgcaccag gagtattgtc agtaacataa aagtattctt ttcggtttcc
     6901 acatagtatc tctatttttg ctgttgcata atcagcacgc attttagacg attgaagttc
     6961 gcctgtgaat cttaatgtac cttttatact agatacttca ttgtaaacga tgctaggagt
     7021 gtttacaatt gtagcctgaa ttctattttt taaagaaaaa atttctattg attgaaaaac
     7081 ccagttaact ttttcaatca aattagtaaa tgtttcagat gatgttgctg aaacattttt
     7141 agaattaatt gtctccacta atacattttt taatgtttct atttttgttt tagttgtacc
     7201 aaatttatct gttccaataa aaggactacc caatgcacta gatatattat ttttaccagt
     7261 ttgaaaatca gcttgtacat tttctaatgt agtcataagt tcctctaaac tagcattatc
     7321 agttaacttt gttgtcatat tttcacctcg cttatatcat atctattaaa ttatttacta
     7381 tagtaattcc tttagtcctt tggccactta tttctaccat tatttcttct aataccccat
     7441 ctaacttatt acttgtaaat ctattattag catctgtaat acttatactg gtatctataa
     7501 gctgtatacg gctaatagaa tcctctattt tcttagacga ataagtagtc atttcagaca
     7561 ctctgttatc atccacagtt gcattaataa aatgagtttc tgcatttcca tttatcacat
     7621 agacatttaa ttcaactttt acctcacttc taatttctat agaattatca tctataattt
     7681 taaagtttgt aactacattt tcttttgtag tagcatctat aatatttaca actattctct
     7741 gtgttaacaa accatgtgtt acagttgctt tgaatccact ttctgcatcc tccacccaat
     7801 catcaattgt tatcgtttgg gtagatgcca catttgaacc acctgcgatt aattggtca
//
LOCUS       DAJMZY010000144         7813 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.147, whole genome shotgun sequence.
ACCESSION   DAJMZY010000144 DAJMZY010000000
VERSION     DAJMZY010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7813)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7813)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7813
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.147"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            316..1617
                     /locus_tag="OE968_003444"
     CDS             316..1617
                     /locus_tag="OE968_003444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HCP7220677.1"
                     /translation="MGKSKDVEIEKSILGTILLDNKLSYKLDELNENMFMNDICLEIF
                     KIMKELKKENIVIDVATVKSKIDRKSLAIKTSDVTNLITWGQNFGLDGHIKILKENLA
                     RRSINQNCQNLLHSLNLGENIDTCIYKFESNIKEILDKDTYENDDVNSIAGKVLDFLE
                     NKKDIGFKFGIKLLDTTIGGLFKGELTTIAAKSGVGKTALALQIMLNSFKQGKKTLFI
                     SREMTSEQVFMRNICRVTGVSTRNMKSKEIDENDWKLIVNAIGDLSENNLIYINDKID
                     TISAIRKRIRQVKPDLLIVDYVQLLTSQKSMDKREREVATFSRELKNMTLDFNIPVIQ
                     LSQLNDEMKDSRPYGDRPMRDSKAIYHDSNNVVYIHQLKGSDYEEAVRDIGESEEAVR
                     ASEYRGIKMVDLIVAKCRDGQTRHKHFCYFGDKLHFQELNY"
     gene            1693..1968
                     /locus_tag="OE968_003445"
     CDS             1693..1968
                     /locus_tag="OE968_003445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HCP7220678.1"
                     /translation="MLELRKIIELLEEHKIEVSIPKELHKYSLLEYLELCQQSGGTYF
                     YIKTLEGALKEARNELMIKLFNGKNYMELARMFEMSVINVRHIVRKK"
     gene            3411..3641
                     /locus_tag="OE968_003446"
     CDS             3411..3641
                     /locus_tag="OE968_003446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HCP7220679.1"
                     /translation="MSNKKKKYANILANECVACGSCIKACPRSAISVPCGISAKINRD
                     LCVGCGICEKICPASVIEIITILKEEEGKCHE"
     gene            3634..4215
                     /locus_tag="OE968_003447"
     CDS             3634..4215
                     /locus_tag="OE968_003447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HCP7220680.1"
                     /translation="MNNKKHWYDYLWIFSSIYLILGFVNIIFAWIGLICFFVPLAISI
                     VKGNKAYCNKYCGRGQLFNLLGNKLKLSRNRDIPKFIRSKWFRYGFLTFFMVMFANML
                     FSTYLVFEGSRNFKEVVTLLWTIKMPWQWAYHGTLVSPWVVQFAFGFYSVMLTSTVLG
                     LITMILFKPRSWCVYCPMGTMTQMICKAKSKSI"
     gene            complement(4790..5467)
                     /locus_tag="OE968_003448"
     CDS             complement(4790..5467)
                     /locus_tag="OE968_003448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HCP7220681.1"
                     /translation="MISQNEIDILTHSLPFWDKLTDLQKELLISSANTSHYKKGNPVH
                     CGDSDCIGILIIKSGTVRTYILSDEGREVTLFRLDDGDVCILSASCILKTITFDVYVD
                     AETDCDIIQISSSVFAKLSTENIHAELFSYKLATERFSDVMWAMQQILFMSFDKRLAS
                     FLIDEIAKNGSSTINMTHEQIAKYMGSAREVVSRMLKYFAREGIVSLSRGGIKVLDKD
                     KLRSLTL"
     gene            complement(5656..7020)
                     /locus_tag="OE968_003449"
     CDS             complement(5656..7020)
                     /locus_tag="OE968_003449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HCP7220682.1"
                     /translation="MKESNKRIELLGSAPISKALLSMGLPTMIGMMITALYNLVDAYF
                     VGGLGTSQMGAISVAFPLGQLVVGLGLLFGNGAASYIARLLGHGDNEKAGKVVSTSIY
                     SSIIVGTLVIIVIMIFLNPILKLLGATKSIMPYAISYASIYVVSSIFNIFNVTMTNIV
                     TSEGAAKTTMCAMLLGALLNMILDPIFIYTFGLGVRGASIATAISQIASTLVYVGYIL
                     SKKSIFSFRINECCFSKEIFSEILKIGIPTLIFQLLTSLAITLTNMEATKYGDSVIAG
                     MGAVTRITSLGSLVVFGFIKGFQPIAGYNFGSKNYDRLHIAIKTSILWTTIFCVVLGL
                     ILILFPKSIISQFTSGDILLIENGSKALRANGFSFMLFGFYTVYSTLFLALGKAKEGG
                     FLGMCRQGVCFIPIILIIPVFYGLNGILYAQPIADLMAAIIAGFMSIRLHKELNLLKI
                     NGMH"
     gene            7148..7669
                     /locus_tag="OE968_003450"
     CDS             7148..7669
                     /locus_tag="OE968_003450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HCP7220683.1"
                     /translation="MATIDLIVLGIVKQQPKSAYDIQKAVEYRNISRWVKISTPSIYK
                     KVIQLEQKGYIESKTVKNGKMPEKAVYSLTELGETHFLDLMFDTSSKPINILLDFNAV
                     IVNLNSLTPEKQKLCLNNIEENVQELKKTIEENISIKTEVPDTAKAVLEQQLVLAQAL
                     ETWINSLKDNMGN"
BASE COUNT         3050 a          876 c         1350 g         2537 t
ORIGIN      
        1 tgaattatat tgaacgatat attaataatt ggcagtaagt tatatcaaat aagatattac
       61 tatcaagtag tgaattatat tgaacaatat attaataatt ggtagtaaag tatatcaaat
      121 aagatattgc tattatgtag taaattatat aaaacaatgt atcagaataa atagtatatt
      181 aataatttgt agtatatcat gacgaataat acagtcataa caaatagtga gtcataacaa
      241 ataatgtatt tataattgat aatgtattta aaaatcaaaa tataaaaact tataaggaaa
      301 gagagattaa tttatatggg taaatcaaaa gatgttgaaa tagagaagtc tattttaggc
      361 acaattcttt tagacaataa attaagctat aagctagatg aattaaatga aaacatgttt
      421 atgaatgata tatgtcttga gatatttaaa attatgaaag aacttaaaaa agaaaacata
      481 gtgattgatg tggccactgt gaaatcaaag atagatagaa aatctctagc aataaaaacg
      541 agtgatgtga ctaatctaat tacttggggt cagaattttg gtcttgatgg tcatattaaa
      601 attttaaaag aaaatttagc tagaagaagc ataaatcaaa attgccaaaa ccttttacac
      661 agcctaaacc ttggagaaaa tatcgatact tgtatttaca aatttgaaag taatataaag
      721 gagattttgg acaaggatac ttatgaaaat gatgatgtaa atagtatagc agggaaggtg
      781 cttgattttt tagaaaacaa aaaagatatt ggatttaaat ttggtataaa attacttgat
      841 accactatag gaggtctttt taaaggagag ctaaccacaa tagcagctaa atcgggggtt
      901 gggaagactg ctttggcact tcaaataatg ttaaattcat ttaagcaagg taaaaaaact
      961 ttatttataa gtagagaaat gaccagtgag caagtattta tgagaaatat atgcagagta
     1021 actggtgtaa gtacaaggaa tatgaaatct aaagaaatag atgaaaatga ttggaaactt
     1081 attgtaaatg ctataggtga tttaagcgaa aataacttaa tttatattaa tgataagata
     1141 gatacaatta gtgcaattag aaagaggata aggcaggtaa agccagattt attaatagtg
     1201 gattatgtgc aactccttac atctcagaaa agcatggata agagagaaag ggaggtagct
     1261 actttttcga gagaacttaa aaatatgact ttagatttta atatacctgt aatccaatta
     1321 agtcagttaa atgatgaaat gaaagattca agaccttatg gagatagacc tatgagggat
     1381 agcaaagcca tctaccacga tagcaacaat gtggtttata tacatcaatt aaaggggagt
     1441 gattatgaag aagcagtgag agatattgga gaaagtgagg aggcagttag agcatcagaa
     1501 tacaggggaa ttaagatggt tgatttaata gttgcgaagt gtagagatgg acagactagg
     1561 cataagcatt tttgttactt tggggataag ttacattttc aagaactaaa ttattaggtc
     1621 aataaagtag taataacaag cttattaaaa gtcgggaaat agcaaataga ttataaaata
     1681 tgaggtgaaa atatgttgga attaagaaaa attatagaat tacttgaaga acacaagata
     1741 gaagtaagta ttccaaagga gttacataag tatagtttat tggaatacct tgaattgtgt
     1801 caacaaagtg ggggaacata tttttatatt aaaacactgg aaggggcttt aaaagaggct
     1861 agaaatgagc ttatgattaa attgtttaat gggaaaaatt atatggaatt agcgaggatg
     1921 tttgaaatga gtgttattaa tgtcaggcat attgttagaa aaaaatagat atttttggag
     1981 aatacaagtg tgatatactt ctgaaataga agttattata gttgaaataa aattgtggtt
     2041 aataaattaa agttgtgtat aagtttaaga ttatagagga gtataagtgt gattaacagc
     2101 atgattttgt gaataaaatt gaggatatat atgagttaaa tgtgtgatta ataaggtaag
     2161 gttgtgtata agattatgag tatttaaaag gaggggctat aattaatagt gtagagttgt
     2221 gtgtttgctt aagattatat aataatttaa tagattaaac tatactaata aggtaaaatc
     2281 gtgtgtttag ttaaagctta ttataaaatc ttgatatgtg attaatgatg caatatgtga
     2341 ataaagttaa gattataata gatttaacct gtggctaata gaataaaatt gtgaataaag
     2401 ttaagattat aataggttta acctgtgatt aatagagtaa gagtgtaaat agagataaac
     2461 ttcaatatga gcttaaccta tgattaatag agtaagagtg taaatagaga taaacttcaa
     2521 tatgagctta acctatgatt aatagagtaa gagtgtaaat agagataaac ttcaatatgg
     2581 gtttaacttg tgattaatag agtagggtgt aactaaagat aaacttcaat atgagtttaa
     2641 cttgtgatta atagagtaag gtgcaactaa agataaactt caatatgagc ttaacctatg
     2701 attaatagag taagaatgta aatagagata aacttcaata tgggcttaac ttgtggttaa
     2761 tagagtaaga gtgtaactaa agataaactt caatatgggt ttaacttgtg gttaatagag
     2821 taagaatgta aatagagata aacttcaata tgagcttaac ttgtgattaa tagagtaaga
     2881 gtgtaaatag agataaactt caatatggga ttaacttgtg attaatagag taagagtgta
     2941 actaaagata aacttcaata tgagcttaac ctatgattaa tagagtaaga atgtaaatag
     3001 agataaactt caatatgggt ttaacctgtg gttaatagag tagggtgtaa ctaaagataa
     3061 acttcaatat gagtttaact tgtggctaat agaataagat tgtgaataaa gttatagttt
     3121 tagatgggta ttaacctgtt actaatagaa tatgattagg tgtaaaatta tagagctgta
     3181 taagaaaata ttatagatat attaaatatt agataataaa tatttatata gatacacaaa
     3241 agaaaaggcg atatgaagct aaacttaatg acttcatatc gttttttatt tgaaactcct
     3301 ttgtatttag agtgtgattt ttaatattga ggttttatgt gattaagtca cagataaaaa
     3361 gtaagtatct tgatataatt cttatagatt aataatatag ggaggttatt atgtctaata
     3421 aaaaaaagaa gtatgcaaat attttagcaa atgagtgcgt tgcttgtggt agctgtataa
     3481 aagcatgtcc aagaagtgct atctcagttc catgtggcat tagtgcaaaa attaatagag
     3541 atttatgtgt tggatgtggg atttgtgaaa agatatgtcc agcatctgta attgagatta
     3601 taacaatatt aaaagaggaa gaaggtaagt gtcatgaata ataaaaaaca ttggtatgac
     3661 tatttatgga ttttttcttc aatatatttg atattgggat ttgtaaatat tattttcgct
     3721 tggattgggc taatttgttt ctttgttcca ctagctattt ctattgttaa gggaaataaa
     3781 gcttactgta ataagtattg tggaagaggg caactgttta atttgcttgg aaataaattg
     3841 aagctgtcaa gaaatagaga tattcctaaa tttattagaa gtaagtggtt tagatatggg
     3901 tttttgacat tttttatggt aatgtttgcc aatatgcttt tttcaactta tttagtgttt
     3961 gaaggaagta gaaattttaa agaagtagtg actttgttgt ggactataaa aatgccttgg
     4021 caatgggcgt atcatggaac tttagtttca ccttgggtgg tacagtttgc atttggtttt
     4081 tatagtgtta tgcttacatc aactgttctt ggtttgatta ctatgatatt gtttaaacct
     4141 cgttcatggt gtgtttattg ccctatgggt actatgactc agatgatatg taaggcaaag
     4201 agtaagtcta tatagaaagg ctttatgtga tatttacagt tttgttagag atgagtagta
     4261 ggtttgaata tatatgacaa atatatgagt ataggggcat agatttagtt tgtgtaaggt
     4321 aaactgattt atgcttcttt tttatgtctt agattattgg ctaagtggaa acaatgaatt
     4381 tagatattaa gaattattca gttatttgaa gaaaatagaa taataattaa cattatatga
     4441 atggatattc attacatata agccagttaa tagcaagatt tatttaatat gaaataggtc
     4501 aagtatttaa actaaataag gtcatgacaa ttaatataag tatagatata aaaagattag
     4561 aagttataac ttataaaagg tattctatat aaatagtatg tggaaaatag tcaaattaac
     4621 ttattagaaa caaaaaatat acataaaaaa ataaatgtaa atatcaaata agatactata
     4681 taaaaataga tataagtatc ttttttatta ttgaaattat gaaaatatat ttgatttcac
     4741 acaaaaaaga gtgcctcatg aactaaaaag ttcattttga gacacacttt tacagtgtca
     4801 aagaacgaag tttatcctta tccaatactt ttataccacc acgagataaa gacacaatac
     4861 cttctctagc aaaatatttc aacattctcg atacaacttc tctggcacta cccatatact
     4921 tagcaatttg ctcatgagtc atatttatag tgctactgcc atttttagct atctcatcaa
     4981 ttaaaaaaga tgccaaacgc ttatcaaaac tcataaaaag aatttgttgc atagcccaca
     5041 taacatcaga aaaacgttcg gtagctaatt tatatgaaaa taactctgca tgaatatttt
     5101 ctgtagataa ttttgcaaaa acagaggaac taatctgtat aatatcgcag tccgtttcag
     5161 catctacata gacatcaaaa gttattgttt ttagaataca ggaagctgat aaaatacata
     5221 catctccatc atcaagtcgg aacagtgtaa cctctcgacc ttcatctgaa agtatgtatg
     5281 tacgtactgt tccagacttt ataatcaaaa taccaataca gtcactatca ccacaatgta
     5341 ctggattccc ttttttgtaa tgcgaggtat ttgctgaaga aattaataat tctttttgta
     5401 agtcagtaag tttatcccaa aaaggcaagc tatgtgtaag tatatcgatt tcattttgtg
     5461 aaatcataca atatctcctt tcttaaattg ttataatccc atgatacaag tgaatagata
     5521 aattgacaag tagtttgtta ataggattat ttagtcagat agtaatagta tgatttatgt
     5581 agaaaaaata tgataatata tattcttgct attaatgaga aggtaatatg ttttgatgat
     5641 agtaggtttg tataactaat gcataccgtt tatttttaaa agattaagtt ccttatgtaa
     5701 ccttatagac ataaaaccag caattatagc agccatcaaa tcagctattg gttgtgcata
     5761 taagatacca tttaacccat agaatacagg aataatcaaa attataggga taaaacagac
     5821 accttgtcta cacataccta aaaatccacc ttcctttgct tttcctagtg cgaggaataa
     5881 tgtagaatac actgtataga atccaaatag cataaatgaa aacccatttg ccctaagagc
     5941 tttactacca ttttctatta atagaatgtc accacttgta aattgtgaaa ttatagattt
     6001 tgggaagagt atcaatataa gaccaagcac tacacaaaat attgtagtcc ataatatgga
     6061 agtttttatt gctatatgta atctatcgta gttctttgaa ccaaaattat aaccagcaat
     6121 tggttggaaa ccttttataa aaccaaatac aacaagacta cctaaagacg ttattcgtgt
     6181 tacagcaccc attccagcta tcacagaatc accatacttt gtagcctcca tattagttaa
     6241 tgtaatggca agactagtca ataattgaaa tattaaggta ggtatgccaa tttttaggat
     6301 ttctgaaaaa atttcttttg aaaaacagca ttcgttaatt ctaaaactaa atatactttt
     6361 cttgcttaaa atatatccta cataaacaag tgttgaagca atctgtgaga tagctgttgc
     6421 aatagaagca ccccttaccc ccagaccaaa agtataaatg aatattgggt ctaaaatcat
     6481 attaagcaaa gcacctaata acatagcaca catagttgtt ttagcagctc cttcacttgt
     6541 gacaatatta gtcatagtga cattgaatat attaaaaata gatgacacga cataaatgct
     6601 agcataagat attgcataag gcataatact ttttgtagct cctaacaatt ttaaaattgg
     6661 attgagaaaa atcataatca caataataac taatgtaccc actataatac tactgtaaat
     6721 agatgtactt accacttttc ctgctttttc attatcacca tggcctaaaa gtctggcaat
     6781 atatgaagca gctccatttc caaacaataa tcctaatccc acaacaagct gacctaatgg
     6841 aaatgcaacg gatatagctc ccatttgact tgttccaagt ccacccacaa agtatgcatc
     6901 aaccaaattg tataatgcag ttatcatcat acctatcatg gtaggtaatc ccatagataa
     6961 caatgctttt gagattgggg cagaccctaa taattcaatt cttttgttac tttctttcat
     7021 acttaacact cctcttctat tgacattaag tctaaattat aatactataa attatagtaa
     7081 gtatggaaaa tagtactata atttatagta tttgtcaata gtaagaaaac taaaggagat
     7141 gatttttatg gctacaatag atttaattgt attgggaata gtaaagcaac aacccaagag
     7201 tgcttatgat attcaaaagg cagtggaata caggaatata tcacgttggg ttaaaataag
     7261 tacaccatca atttataaaa aagtaattca attagaacaa aagggatata ttgaaagtaa
     7321 aactgtgaag aatggaaaaa tgccagaaaa agcagtttat tcattaactg aattaggtga
     7381 gacacatttt ttagatttaa tgtttgatac atctagcaaa ccaataaata ttcttttaga
     7441 ttttaatgct gttatagtaa atttaaatag ccttacacca gaaaaacaga aattatgtct
     7501 caataatatt gaagagaatg ttcaagagtt aaagaaaact attgaggaaa atataagtat
     7561 aaagacagaa gtaccagaca cagcaaaagc agtgttggag caacagttgg tgctagcaca
     7621 agcattggaa acctggataa attctttaaa agataatatg ggaaattaga attagagaag
     7681 ctaacttaat aatcattaaa caaaaaccag catatttaat aatgagatat tagaaaaaat
     7741 aaaacaaatg atataaactg aaaagtatat ttaaaataaa gctcacttaa ttgagggaga
     7801 atgttaaact ttt
//
LOCUS       DAJMZY010000145         7673 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.148, whole genome shotgun sequence.
ACCESSION   DAJMZY010000145 DAJMZY010000000
VERSION     DAJMZY010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7673)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7673)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7673
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.148"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            complement(171..1010)
                     /locus_tag="OE968_003451"
     CDS             complement(171..1010)
                     /locus_tag="OE968_003451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HCP7220684.1"
                     /translation="MSDIKNEVSKKTLSKKDVIKSWLRWFFFAQSNYNYERLQSTAFS
                     HSMLPVLKKLYPDKEELKQEVETHLAFFNTEPICGCVIHGITIAMEEEKANGADEISG
                     DGMNAIKTGLMGPLAGIGDTLTQGVITPIVLAVCIGLTEGGASIAGPILFVIAQYIIM
                     TSISFGMWTNGYKYGKKAVESILQGGIVNKVIEGASILGTLVMGGLVGRFINLSTPIS
                     YTSGDFKFSLQTDLLDKIFPGLIPLVLTLLVLFALKKGLSPIKIMFILIVVGAITGIL
                     GLF"
     gene            complement(1034..1792)
                     /locus_tag="OE968_003452"
     CDS             complement(1034..1792)
                     /locus_tag="OE968_003452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCP7220685.1"
                     /translation="MHISLIQAVLIAIFYYLSWSPWLTYVGFFTWNRPLLAGFVTGII
                     LGDPVQGAIIGAGINMIYLGFISAGGAQMGDPAFAGYVGTALAIASKLDVSTAMAIAV
                     PLGTVATVLWIGKMTVNSFFAHWADREVQKGNVDRVAFINIVPPQILLFAMSFIPALL
                     VVYFGPNAIDGMLEVMNDNVLHVFNVIGAMLPALGIAMNLKLIGNKFTMPFFILGILM
                     AVYFKVDIIVISVIGVILALTITSIKYGKDSATS"
     gene            complement(1839..2312)
                     /locus_tag="OE968_003453"
     CDS             complement(1839..2312)
                     /locus_tag="OE968_003453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCP7220686.1"
                     /translation="MSNIALTRIDDRLIHGQVITAWCKITSAKRIVIVDDLVVKDPFI
                     VQVLQMAAPSTVKVEVHDVESGAEVLKSYNGDENLIVLVKYPKTVLGLVNSGVDLKEL
                     NVGGMGAGLGRKSFYKNISVSDEEKEIFRELISKDVKCFIQIVPDAKKIDVGTLL"
     gene            complement(2341..2757)
                     /locus_tag="OE968_003454"
     CDS             complement(2341..2757)
                     /locus_tag="OE968_003454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HCP7220687.1"
                     /translation="MIHMAGIIIATHGNMAKAMLESAELIVGKQENVETLGLNHGDSI
                     DEFSRKLEDGIEKYKDEGVLVLLDFYGGTPFNTSAIIINKFAKVCELECLTGVNLPML
                     LELFLNRDTMKLKDLKNLCEEVGISGIKDVKTVLKL"
     gene            complement(2804..3856)
                     /locus_tag="OE968_003455"
     CDS             complement(2804..3856)
                     /locus_tag="OE968_003455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HCP7220688.1"
                     /translation="MKSVRFYGIRDTRVEDVDVPKILEKDDVIIKVKVAGICGSDISK
                     YSKTGPHMVGEILGHEFSGEVAQVGKEVRSFKIGDRVAVCPAMPCFECDECKKGLYSR
                     CNNVAIIGNKELGGCFAEYTKVKERNLIKIPDEISYETAAALEPVCIAGHGLFRSEAK
                     VGDTVVVLGTGPIGLFSIQWAKIFGSTKIIAVDVFDEKLDLAKELGADICINAKEKNI
                     VEEIKRLTDGDGADIVIESAGTPLTCGQVLLLAKKGGTVLYAGVPYGDVALTREQFEK
                     IVRSELTVKGTWFGNSFPFPGKEWSAGLYHMQKGDMNVEKLVTHRINLEEVPAYFEKV
                     YKRDIFFGKIMINIDN"
     gene            4252..4932
                     /locus_tag="OE968_003456"
     CDS             4252..4932
                     /locus_tag="OE968_003456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HCP7220689.1"
                     /translation="MKKVYQGKTKDVFELDNGNYLLKFKDDVTGKDGVFDPGENSVGL
                     SIDGIGRANLETSVKFFEILNNAGIKTHYVSANLEEATMEVLPAKVFGNGLEVICRYR
                     AVGSFLRRYGSCVEEGAKLDCYVEATLKDDDRCDPLITSEGLEALNIMTQAQFDSMKS
                     MTQKISNIVRDTIAEKGLELYDIKFEFGFYNDEVILIDEIASGNMRVYKDGVIVDPMD
                     LTALLLDK"
     gene            complement(5065..5385)
                     /gene="sugE"
                     /locus_tag="OE968_003457"
     CDS             complement(5065..5385)
                     /gene="sugE"
                     /locus_tag="OE968_003457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000118520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quaternary ammonium compound efflux SMR
                     transporter SugE"
                     /protein_id="HCP7220690.1"
                     /translation="MKWLFLFVAGLFEVFWAFQLKNSHGFSKLTPSILTVVGMIVSFY
                     FLSLALKHLPLGTSYAIWTGIGTVGTAIVGMAILNEPISISRIACIGFIVVGIVGLKL
                     LSTN"
     gene            5767..6594
                     /locus_tag="OE968_003458"
     CDS             5767..6594
                     /locus_tag="OE968_003458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-nitrogen hydrolase family protein"
                     /protein_id="HCP7220691.1"
                     /translation="MNFYKIAVCQMITTENKIENINHAVDMVTEAAINGSKIVVLPEM
                     FNCPYENKYFPKFAEEYPGETTTILSKLAEKHGIYLVSGSIPELEDGKIYNTCYVFDK
                     NGALIGKHRKMHLFDIEVTGKVSFKESDTLTAGNDVTVIDTEYGKVGIAICYDIRFPE
                     LSRLMALKGAEIVILPAAFNMTTGPAHWELSIRMRALDNQIFYVGAAPARNMNASYIA
                     FGNSRISDPWGRIIAQADEKECIIYADIDRDLIPDIRQQLPLLKHRRTDLYELNTLK"
     gene            7416..>7673
                     /locus_tag="OE968_003459"
     CDS             7416..>7673
                     /locus_tag="OE968_003459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HCP7220692.1"
                     /translation="MNNKILVVDDEEGIITLLKDYFEMNGYEVYTAQSGKGALKKISK
                     NPDIILLDINMPEIDGIEVCNRIRDYVSCPILFLTARIENTD"
BASE COUNT         2620 a         1360 c          907 g         2786 t
ORIGIN      
        1 ttctgagata ctttttaaaa tattaaatac tacatatagc ttacataagt ttaaaattta
       61 atctattata aaattaccct aattgccaaa ctttttaata taaattttcc aacatcctac
      121 aaatataatc aatagatata gaatcctaac ttacaccaat atatatttat ttaaaatagt
      181 cctaaaatac ctgtaatagc tcccactact atcagtataa acattatttt tattggagaa
      241 agaccttttt ttaaagcaaa gagtactaat aaagtaagta ccaaaggaat taacccagga
      301 aatatcttat cgagtaaatc cgtttgaaga ctaaatttaa aatcaccact agtataactt
      361 attggtgtag ataaattaat aaacctacct acaagtcccc ccatgactaa ggtacctagt
      421 atagaagccc cttctataac cttatttact attccacctt gaagtatact ttcaacggct
      481 tttttcccat acttatatcc atttgtccac attccaaaag aaattgaagt cattattata
      541 tattgagcta ttacaaataa tataggtcct gcaattgatg ctcctccctc agttaaacca
      601 atacaaacag ccaacactat aggagttata actccttgag ttaaagtatc gccaattccc
      661 gctagtggac ccatcaagcc tgttttgata gcattcatac catctccact tatttcatct
      721 gctccattag ctttttcttc ttccatagct attgttattc catgtataac acatccacat
      781 ataggttctg tgttaaaaaa tgctagatga gtctccactt cttgttttaa ctcttcctta
      841 tctggatata attttttaag tactggcaac attgaatgtg aaaaagctgt tgattgcaat
      901 ctttcataat tgtaattaga ttgtgcaaag aaaaaccatc ttaaccatga ttttattaca
      961 tctttcttgc ttaacgtttt cttagatact tcatttttta tatctgacat aatattttcc
     1021 ccctcacatg tatttaagat gtagcactat cttttccgta cttaattgaa gtaattgtaa
     1081 gagcaagtat tactccaata acagatatta ctattatatc tactttaaaa taaacagcca
     1141 ttagtattcc taatatgaaa aagggcatag taaacttgtt tccaatcaat tttaaattca
     1201 tagcaatccc aagtgctggc aacatagccc caattacatt aaatacatgt aacacattat
     1261 cattcattac ttccaacata ccatctatcg catttggacc aaaataaaca actaataatg
     1321 ctggtataaa actcattgca aataacagta tctgtggtgg tactatattt ataaatgcta
     1381 ctctatcaac attccctttt tgaacctctc tatcagccca atgtgcaaaa aaagaattta
     1441 ctgtcatctt tccaatccaa agtacagttg caacagttcc caatggtaca gctattgcca
     1501 ttgcagtact tacatctagc ttagatgcta tagctaaagc agtacctaca tatcctgcaa
     1561 aagctgggtc ccccatctga gctccccctg ctgatataaa acctagatat atcatattta
     1621 tacctgctcc tataattgct ccttgaacag ggtctcctaa tataattccc gttacaaatc
     1681 cagccaatag aggtctattc catgtaaaaa atccaacata agtcaaccac ggactccaag
     1741 aaagataata aaaaattgct attaatactg cttgaattag tgaaatgtgc atattcttcc
     1801 tccctatttt cttttaaaga tttacaagat agtcttcttt acaataatgt tcctacatca
     1861 attttctttg catctggtac tatttgtata aagcatttaa catcttttga tattagctct
     1921 ctaaatattt ctttttcttc atctgacaca gatatatttt tataaaaact ttttctacca
     1981 agccctgctc ccatacctcc aacattcaat tcctttaaat ctaccccgct atttactaaa
     2041 cctaagacag ttttagggta tttgaccaat actattaaat tttcatctcc attatatgat
     2101 tttaagactt cagcacctga ttctacatca tgtacttcaa ccttaacagt tgatggagct
     2161 gccatttgta aaacttgaac tataaatggg tcctttacta ctaaatcatc cacgattact
     2221 atcctttttg ctgatgtaat cttacaccaa gcagtaataa cttgcccatg tattaatcta
     2281 tcatcaattc ttgttaatgc tatattactc ataattattc ctccagattt ttaatttatt
     2341 ttacaacttt aaaacagttt taacatcttt gattcctgat atcccaactt cctcacataa
     2401 attcttcaag tcttttaact tcatagtatc tctgtttaaa aataactcta aaagcatagg
     2461 taaatttaca cctgtcaaac attctaactc acatacctta gcaaatttat ttattataat
     2521 agcagatgta ttaaatggag ttccgccata aaaatcaagc aatactaaaa ccccttcatc
     2581 cttatatttc tcaattccat cttctaactt tctactaaac tcatctatgc tgtcaccatg
     2641 gtttaatcct aaagtttcta cattttcctg tttgcctact attaattcag cactttctaa
     2701 cattgcttta gccatatttc catgtgtggc tataattatt cctgccatat gaatcatacc
     2761 tttcttaacc ttttttatat ggattattat ttagtactct aatctaatta tctatattaa
     2821 tcattatctt accaaagaaa atatcccttt tgtatacttt ttcaaaataa gctggtactt
     2881 cttctaaatt tattctatgt gttactaatt tttcaacatt catgtcaccc ttttgcatat
     2941 gatacaatcc agcactccat tcttttcctg ggaatggaaa ggagtttcca aaccaagttc
     3001 cctttacagt taattcactt cttactatct tttcaaattg ctctctagtc aaagctacat
     3061 ccccatatgg tacacctgca tacaatactg tacctccctt tttagctagc aacagtactt
     3121 gaccacatgt cagtggagta ccagccgatt caataacaat atctgcacca tctccatcag
     3181 ttaacctttt tatttcttct acaatattct tttcttttgc atttatacaa atatctgccc
     3241 ctaactcttt tgccaagtct aacttctcat caaatacatc cacagctatt atttttgtag
     3301 aaccaaatat ttttgcccat tgtattgaaa ataatcctat tggacctgta ccaagtacta
     3361 caacagtatc tccaacttta gcttctgacc taaaaagacc atgtcctgct atacatactg
     3421 gttctagcgc agcggcagtc tcataactta tctcatctgg tatttttatt aaatttctct
     3481 ctttcacctt tgtatactct gcaaaacaac ctccaagttc tttatttcct attattgcta
     3541 cattattaca tcttgaatac aagccttttt tacattcatc acattcaaaa catggcatag
     3601 ctggacaaac agcaactcta tctcctattt taaaactcct tacttcttta ccaacctgtg
     3661 ccacttctcc agaaaattca tgccctaaaa tttctccaac catatgtgga cctgtctttg
     3721 aatattttga tatatcagaa ccacatattc cagctacttt tactttaatt attacatcat
     3781 ctttttctaa tatttttggt acatccacat cctccactct tgtgtctctt ataccataga
     3841 atctaactga cttcactatt aaccacccct actttttatt tgagaatata tccctattgt
     3901 ttatatgtta aatatctaaa gcaactttca tgccaatata tgtaagcatt gtattcatgc
     3961 attttataaa attatcatta aatgtgtgtc aaagtgtgtc aaaagtttct tatattaaaa
     4021 cttatgtgtg tcaatataaa cgacactaac attttatatt agttctctta ttataagttt
     4081 tataaaatgt actttttttg ttatttttat aaaattgttc ggaaatttcc cttctatttg
     4141 tgatataata ttaaatataa ggtatcaata taaattttca tgcgaatatc agaacttttt
     4201 tgacactaat gccttattca atataataat ttaacttttt ggaggttgtt tatgaaaaaa
     4261 gtgtatcaag gaaagactaa agatgttttt gaattagata atggaaatta cttacttaaa
     4321 tttaaagacg atgtaactgg taaagatgga gtatttgacc caggcgaaaa tagtgtaggt
     4381 ctaagtatag atggaattgg tagagctaat ttagagacat ctgttaagtt ctttgaaatt
     4441 ctaaacaatg ctggaattaa aactcattat gtaagtgcta atttagaaga agcaactatg
     4501 gaagttctac cagcaaaagt ttttggtaat ggattagaag ttatttgtcg ttatagagct
     4561 gttggtagtt tcttacgtcg ttatggttca tgtgttgaag aaggtgctaa actagattgt
     4621 tacgtagaag caactttaaa agatgatgac cgttgtgacc ctcttataac atctgaaggt
     4681 ttagaagctt taaacattat gactcaagct caatttgatt caatgaaaag catgactcaa
     4741 aaaatttcta acatagttcg cgatactata gctgaaaaag gtcttgagct ttatgatatt
     4801 aaatttgaat ttggattcta caatgatgaa gtaatcttaa tagatgaaat agcatctgga
     4861 aatatgcgtg tttataaaga tggtgtaata gttgacccta tggatttaac tgctctttta
     4921 ttagataaat agtatataca tataatttac aaatataata aacttataaa taagataagc
     4981 tatgaagtaa agacttttta aatgttgatt atttttaaac attttctcgc ctttaatttc
     5041 atagcttatt taaattaata tactctaatt agtagataat agctttaacc ctacaattcc
     5101 caccacaata aaacctatac atgcaattct tgatatacta ataggctcat ttaaaatagc
     5161 catgcctaca atagctgtac cgacggtacc aattccagtc catattgcat atgaagttcc
     5221 aagtggaaga tgttttagtg ctaatgacaa aaaataaaaa cttacaatca ttccaacaac
     5281 agtaagtata cttggagtta atttagaaaa tccatgtgaa ttttttagtt gaaaagccca
     5341 aaacacttca aacaaacctg caacaaacaa aaataaccat ttcataaatt catccctctt
     5401 ttcaaatatg tctcttattt ttccaataaa ataacctgag aaatattata aaatatctcc
     5461 caggtttttg tccttccgtg ttcacaacaa aaactatgtt gtgggtttta tctcggacca
     5521 gaccaatcat taataattgc ggaaccctat aaaactctat taattattct attttatcta
     5581 taataatact atcaacatat ataaaaaaag tcaatatatg ggttccatat ataataaaaa
     5641 taacttttat atacctttta atattcttat tcacttctct ccatacccat ttgggtcaat
     5701 ctaagaatat ctaattttta tttaatatgt tataataaca taaaaatatt gaaaggagta
     5761 atttctatga atttctataa aattgcagta tgtcagatga ttactacaga aaataaaatt
     5821 gaaaatatca atcatgctgt agatatggta acagaagctg ccatcaatgg atctaaaatt
     5881 gtagttttgc cagaaatgtt taactgtcca tatgaaaata aatattttcc taaatttgct
     5941 gaagaatatc caggtgaaac aacaacaata ttgagtaaat tagctgagaa acatggaatt
     6001 tatctagttt ctggtagtat tcctgagtta gaagatggaa aaatctataa tacttgctat
     6061 gtatttgata aaaatggagc tctaattgga aaacatcgta aaatgcactt atttgacatt
     6121 gaagttacag gaaaagttag ttttaaagaa tcagatactc ttacagctgg aaatgatgtt
     6181 actgtaatag ataccgaata tggaaaagtt ggtatagcta tttgttatga tattcgtttc
     6241 cctgagttat cacgtttaat ggctcttaaa ggtgctgaaa tcgttatctt gcctgctgca
     6301 tttaatatga ctactggtcc cgcccattgg gagttatcta taagaatgcg tgctttagat
     6361 aatcagatat tctatgttgg tgctgcacct gctagaaata tgaatgcttc ctacatagct
     6421 tttggaaatt caagaatttc agacccttgg ggaagaataa ttgctcaagc tgatgaaaaa
     6481 gaatgtatta tttatgctga cattgataga gatttaattc ctgacataag acaacagtta
     6541 ccacttctta agcacagaag aactgattta tatgaactta atactttgaa ataaaacaga
     6601 acataacccc ataaatcata aattaagtgt taaaaaaatt tatggggttc tcattaattt
     6661 gatttaaaat taatttcata aaaataatac taatattaat ttaattaaat aatactaata
     6721 attactaatg attatgctaa ttatcagcat ttactaattt aatcactatt agttatttct
     6781 tttattaaat atctttactt tttttactta ttatgtcttc tagctttaca tttggattat
     6841 agtatttctt tctattttta gtcacatctt tctattgaat tacttgctta aaacaccaat
     6901 gcacacattc cagacaatgt tcacaattat gtaaaaatct tgctctacct tcttcaatgt
     6961 tgatattatc tctcctagtt gatattatct ttcctaaaat ttcttttaat taaaaaacaa
     7021 cattcgttga tatatcgagt atattttaag caactgaaaa aaacaataat aattgatata
     7081 tcaactaatt aatgtagatt aattcatttt tataatttat atacttttta attaatctac
     7141 ctttttaatt aaaattcttc ctttctattt atccatttta aacttaaatt ataagatttc
     7201 atcagctgtg tttttgcatt ccaataagta ttaaatatca aatatatatt ctattaaaat
     7261 ttctaataat ttcatccttg atttatttaa tatataaaaa tatactaact ttaatgatta
     7321 agttttgaaa tataactaag aatttgagat tttattgaga tttttatact aaagtataca
     7381 tactatacaa gcttaattta gaagggagca ttcttatgaa caataaaata ctcgtcgtag
     7441 atgatgagga aggtataata acactcttaa aagattactt tgaaatgaat ggttatgagg
     7501 tttacactgc tcaaagtgga aaaggcgcat taaaaaaaat atccaaaaat ccagatatta
     7561 ttctacttga tataaacatg cctgaaatag atggaattga agtttgtaat agaattagag
     7621 attatgtatc atgccctatt ctatttctta cagctagaat tgaaaatact gac
//
LOCUS       DAJMZY010000146         7405 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.149, whole genome shotgun sequence.
ACCESSION   DAJMZY010000146 DAJMZY010000000
VERSION     DAJMZY010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7405)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7405)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7405
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.149"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            474..3116
                     /gene="adhE"
                     /locus_tag="OE968_003460"
                     /gene_synonym="adhC"
     CDS             474..3116
                     /gene="adhE"
                     /locus_tag="OE968_003460"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HCP7220693.1"
                     /translation="MEKKEKVVEKSNVEVCSPEIVNSVETLRMRLEEIRLAQKEFATF
                     TQEQVDKIFLAASTAANQQRIPLAKMAVEETGMGIVEDKVIKNHFASEYIYNAYKDTK
                     TCGVIEKDEAFGFTRIAEPVGVLSAVIPTTNPTSTAIFKSLIALKTRNGIIFSPHPRA
                     KNCTIEAARVVHDAAVKAGAPKGLIGWVDVPSIELTNVVMAEADLILATGGPGMVKSA
                     YSSGKPAVGVGPGNVPAIIDESADIKMAVSSILVSKSFDNGMICASEQAVIVPEKIYE
                     EVKKEFKYRGAHFLNKEETEKVGKVVIIDGSLNARIVGQPAHVIAKMADVEVPKTARI
                     IIGEVESVELNEPFAHEKLSPVLAMYKSKSFEDAVAKAEKLVADGGYGHTSSLYADSI
                     NHPERVEKFVNAMKTCRVLVNTPSSQGGIGDLYNFKLAPSLTLGCGSWGGNSVSENVG
                     VKHLLNIKTVAERRENMLWFRAPEKVYFKKGCLGVAAREFKDVMDKKKAFIVTDSFLY
                     NNGYTKKLTDLLDEMGIKHTTFFDVAPDPTLACAREGAKAMADFQPDLIIAVGGGSAM
                     DAGKIMWVMYEHPEVDFQDLAMRFMDIRKRVYVFPKMGEKAYFAAIPTSAGTGSEVTP
                     FAVITDQDSGVKYPLADYELMPNMAIIDADMMMEMPPRLTAASGVDALTHALEAYVSM
                     LRTEPADGLALQAGKIIFEYLPRAYKNGKNDKEAREKMAMASTMAGMSFANAFLGICH
                     SLAHKLGAFHHVQHGVANALLINEVIKFNCAEAPNKMGAFSQYRYPDCIQRYAEFASF
                     AGIKGSTDQEKVDNLIKAIDELKAKVGLPKTIKEAGVEESKFLERLDAMVEQAFDDQC
                     TGANPRYPLMSELKEIYLKVYYGK"
     gene            complement(3476..3817)
                     /locus_tag="OE968_003461"
     CDS             complement(3476..3817)
                     /locus_tag="OE968_003461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220694.1"
                     /translation="MLLILGNLNLNLDFDYRIIREENDDVDIFIDINYRSLDIDTDGS
                     NLFNSRIQFPFVRALILRLNKNNQCMTIHLLRDIDLFSAFANFEVDYTDSIINIKNQN
                     EKVILNKSIKK"
     gene            complement(3844..4515)
                     /locus_tag="OE968_003462"
     CDS             complement(3844..4515)
                     /locus_tag="OE968_003462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCP7220695.1"
                     /translation="MPILETINLGKIYGKKETSVHALKNANLKINKGEFVAIIGPSGS
                     GKSTFLHLVGGLERPSNGTIKVDGKDICCLSDKELARYRRQKVGFVFQQYNLIPVLNV
                     KENIELPLKLDNKKIDKEYIDDLINLLGLNERKNHLPNQLSGGQQQRVAIARALSAKP
                     SIILADEPTGNLDSKTTEEVMDLLKSSIKKYNQTLIIITHNENIARKADRIISIIDGE
                     LKLTL"
     gene            complement(4527..7103)
                     /locus_tag="OE968_003463"
     CDS             complement(4527..7103)
                     /locus_tag="OE968_003463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HCP7220696.1"
                     /translation="MKDNLKIVLRYIKSYKARSLAIVVSIILATSLVVGIGTLSRSAQ
                     QADVDRLKRELGTDHVYFKNIKKNQLKSIKSSKDIKNLGITSYYASTDVNEKLPINIL
                     YANKNYLTSHSKLIKGRFPKASNEVVVEKWILNSMGLKPEINQNLTFKLYQKENPETF
                     KVVGILEDRFIEKKKGQCEIFSNLNESELNDFTTYIEFNEGSDINTNIDNIIKNAMLD
                     EKSIGRNSMLIESTMKNGTLDNSSKYVAIAMSLFAGIVIYSIYVISIYQRVQEYGVLR
                     AIGSTNFRIFKLMLYELFILALIAMPIGICIGMGGAQIFNRSVGNIQFEGNINVTPFV
                     IPDKIILLSIACTILIILIISFFTYLKIRRISPIDAIRKTFGADKNVTKVNYLISKLT
                     LNMSVTKSISAKNIFRNKKGFIIIVLSMSIGGIIVIKDNYKYSFLDVQNKSTQEQTYM
                     NADFILSNVYLNEIGNNTSFKDIKGFNDNQIDKIKNIDGIDKVKTASILNTRIEVNKI
                     NRLDYYEAINSTPYYKLNPLFIKNKTTGKYTLKQKLKGYNDEMIKSLEKYLVSGNINL
                     KKMKKENLAIVYVPEISKTQKYTKTFTPGEGTPAVDIKVGDTIKVKYPKGGMDTGLYE
                     SLKDNYEYLEYEFKVGAIISYPFADNGMYSGDDGVDVITSSEYLKKLTGVDKYNLVYA
                     DLNENANKKKINNLLGKIGSEVPGTTTVDMMVEKENSDKMTSRTMIYSYGIVAIMFII
                     SVLNIINNISYNLTSRTSEFGMLRAIGISERGFKNMILYEGILYGVLSSIITIVSGII
                     IQFKMYYMQGFVSYGLGFSIDYKIYILVILANIIVGILATYIPSRKINKISIVEAINI
                     TE"
BASE COUNT         2611 a         1040 c         1081 g         2673 t
ORIGIN      
        1 gattagaata attttagttt atatattttt taaaactata cagttgttat aaaaagaaaa
       61 attgcataca agtcaaaaat aagtgttatt ttataaaaat acgacaaaaa ttttatttac
      121 tacttataca aataacatgc aaataacata taaaatttaa taagtaaaaa aaatgaaaga
      181 tataaattat cattttagta ttttatttag tcgaagtaaa ttattcaaat gaaatatatc
      241 tcatttagat aaaaaatttt agtaaaagta aaaaaaataa tatatttgtt aaaaaataaa
      301 ttgacaaaat attcagaaaa aaacttcttg acctaagaga gtaaaataaa taaaatctaa
      361 ggtatagaga tgaaatctat aaaattattt taagtataag ttaaaaatat agatgatgca
      421 tttaagatta ataaaaatta gagatgcata attattttag ggaggttttt agtatggaga
      481 aaaaagaaaa ggtagtagaa aaatcaaatg ttgaagtatg tagtcctgaa attgtcaaca
      541 gtgttgaaac attaagaatg agattagaag aaattagatt ggcacaaaaa gaatttgcaa
      601 catttacgca agaacaggta gataagattt tcttagctgc ttcaactgca gctaatcaac
      661 aaagaatacc tctagcaaaa atggcagtgg aagagactgg tatgggtatt gttgaagata
      721 aggttataaa aaaccatttt gcctcagaat atatctataa tgcttataaa gatactaaaa
      781 cttgtggtgt catagaaaaa gatgaagcat ttggttttac aagaattgct gagccagtag
      841 gtgttttatc agcagttata ccaacaacta atcctacatc aactgcaata ttcaaatccc
      901 taatagcact aaaaactaga aatggtataa ttttctctcc tcatccaaga gctaaaaact
      961 gtactataga agcagctaga gttgtacatg atgcagcagt taaggcagga gcaccaaaag
     1021 gacttatagg ttgggtagat gttccttcga ttgaattaac taatgttgtc atggcagagg
     1081 cagaccttat attagctact ggtggacctg gaatggttaa atctgcatac tcttcaggta
     1141 aaccagctgt cggagttggg cctggaaatg tacctgcaat aatagatgag agtgcagata
     1201 taaaaatggc tgtaagttca atcttagtat caaaatcatt cgataatggt atgatatgtg
     1261 cttccgagca agctgtaata gtaccagaaa aaatatatga agaagttaaa aaagaattta
     1321 aatatcgtgg agcacatttc ctaaataaag aagaaactga aaaagtagga aaagtagtaa
     1381 taattgatgg ttcattaaat gccagaatag ttggacaacc agcacatgta atagccaaaa
     1441 tggcggatgt agaagttcca aaaacagcta gaataataat tggtgaagta gaatctgttg
     1501 aattaaatga accttttgca catgaaaaac tttctcctgt acttgcaatg tacaagtcta
     1561 aaagttttga agatgcagtt gctaaagcag aaaaattagt tgcagatgga ggctatggtc
     1621 atacatcttc attatatgca gactctataa atcatccaga gagagtagaa aagtttgtaa
     1681 atgctatgaa gacttgtaga gtattagtta atactccatc atcacaaggt ggtataggtg
     1741 atttatataa ctttaaattg gcaccgtctc ttactcttgg ttgtggttct tggggtggaa
     1801 actcagtatc tgaaaacgtt ggagtaaaac atttgcttaa tatcaagaca gtagctgaaa
     1861 ggagagagaa tatgctttgg ttcagagcac cagaaaaggt ttatttcaaa aaaggatgtt
     1921 taggtgtagc agcaagagaa tttaaggatg ttatggataa aaagaaagca tttatagtaa
     1981 cagattcttt cctatataat aatggatata ctaagaaatt aactgattta ttagatgaga
     2041 tgggaattaa gcatactaca ttctttgatg tagctccaga cccaacatta gcttgtgcaa
     2101 gagaaggagc taaagctatg gctgatttcc aaccagattt aataatagct gtaggtggag
     2161 gaagtgcaat ggatgctggt aagataatgt gggtaatgta tgagcatcca gaagtagatt
     2221 tccaagactt agctatgaga tttatggata taagaaaaag agtatatgta tttcctaaga
     2281 tgggtgaaaa agcgtatttt gctgctatcc caacttcagc aggaactggt tcagaagtaa
     2341 ctccatttgc agttataact gaccaagatt caggtgtaaa gtacccatta gcagattatg
     2401 aattaatgcc aaacatggct ataattgatg ctgatatgat gatggagatg ccaccaagat
     2461 taacagcagc atcaggtgtt gatgctttaa cacatgcatt agaagcatat gtatctatgt
     2521 taagaactga accagctgac ggtctagcac tacaagcagg taaaataata tttgaatatt
     2581 tacctcgtgc atataaaaat ggaaagaatg ataaagaagc aagagaaaaa atggcaatgg
     2641 catctactat ggcaggaatg tcttttgcaa atgccttctt aggaatatgt cactctttag
     2701 cacataaatt aggtgcattc caccatgttc aacacggtgt tgcaaatgca ttattaataa
     2761 atgaagtaat caagttcaat tgtgcagaag ctccaaataa aatgggtgca ttctcacaat
     2821 acagatatcc tgattgcata caaagatatg ctgaatttgc ttcttttgca ggtattaaag
     2881 gaagtacaga ccaagaaaaa gtagataatc ttataaaagc aatagatgaa ctaaaggcaa
     2941 aagtaggtct tcctaagact ataaaagagg ctggagtaga agaatctaaa ttcttagaaa
     3001 gattggatgc tatggttgaa caagcttttg atgaccaatg tacaggtgct aatcctagat
     3061 acccattgat gagtgaatta aaagagatat atctaaaagt ttattatggt aaataatatc
     3121 tattgtgcaa cataggttct attgggtttg tatataaatt attagatttg aatataaata
     3181 gagttttatt agagacacgt agaagtaact ataaataata gattataact taaattctaa
     3241 atggaaatga taaaaagtca gtaatttaat ggtaatttcg aatatgtgta tttaatcaat
     3301 taactttaaa attagtcgga aaattttttt attacatata attttaaagc ataatatata
     3361 aaaaacttta tgaaaaaatt ataaaaatat tcagaaaatt ctattgacta atttatttat
     3421 catgatataa taagtttaga aaagaaaaaa attggggcct attaaggccc ccttactatt
     3481 ttttgataga tttatttaaa attactttct cattttgatt ttttatattt attatagagt
     3541 cagtataatc cacttcaaag ttggcaaaag cagagaataa atctatatct cttaacaaat
     3601 gaattgtcat acattgattg ttcttattta gccttagaat caatgctctt acaaatggaa
     3661 attgtattct agaattaaat aagttagaac catcagtatc tatatctaag ctacgataat
     3721 taatatctat aaatatatct acatcatcat tttcttctct tattattctg tagtcaaaat
     3781 ccaagtttaa atttaaatta cctaaaatca ataacattta aatcctcttt tctataaata
     3841 gttttagagt gttaatttaa gctctccatc tattatagat ataattctat ctgcttttct
     3901 agcaatattt tcattatgtg ttattattat aagggtttgg ttatattttt ttatagaact
     3961 ttttagtaaa tccatgactt cttctgtagt tttactgtcc aaatttcctg ttggttcatc
     4021 tgctaggatt atacttggtt ttgcagataa agcacgtgca atagcaactc tttgctgttg
     4081 accaccagat aattggttgg gaagatgatt tttcctttca ttaagaccca ataaatttat
     4141 aaggtcatca atatattctt tatctatttt tttattgtct aactttagtg gtaattctat
     4201 attttccttt acatttaata caggaattaa gttatactgt tgaaagacaa atcctacctt
     4261 ttgtcttcta tatcttgcta attctttatc tgaaagacaa catatatctt taccatctac
     4321 ctttatagta ccattacttg gtctttcaag accacctact aaatgtagaa atgtactttt
     4381 cccacttcca cttggtccaa ttatagcaac aaattcgcct ttatttattt ttaaatttgc
     4441 attctttagt gcatgtacag atgtttcctt tttcccataa atcttaccta aattaatagt
     4501 ttccaatata ggcataatta tccctcctat tctgtaatgt ttatagcttc aactatacta
     4561 attttattta tctttcttga tggaatatat gtagctagaa taccaacaat tatatttgct
     4621 aaaataacta ggatatatat tttgtaatct attgaaaatc ccaatccata tgatacaaag
     4681 ccctgcatat aatacatttt aaattgtatt ataattcctg acacgatagt aattatactt
     4741 gagagtacac catataatat tccttcataa agtatcatat ttttaaagcc tctctcagag
     4801 ataccaatag ctcttaacat tccaaattca ctagttcttg aagttaagtt ataacttatg
     4861 ttgtttatta tgttaagtac actgattatg aacattattg ctactatacc ataactataa
     4921 atcatagttc tagatgtcat cttatcagaa ttttcttttt ctaccatcat atctactgtt
     4981 gtagttccag gaacttcact tccaatttta cctaaaaggt tatttatttt tttcttgttt
     5041 gcattttcat taaggtctgc ataaactaag ttatacttat ctacaccagt taattttttt
     5101 aggtattcgc tactcgttat tacatctaca ccatcatctc cagagtacat accattatct
     5161 gcaaaaggat aacttataat agctccaact ttaaattcat attctaagta ttcataatta
     5221 tcttttagac tttcataaag ccctgtatcc atcccaccct ttggatattt gacttttata
     5281 gtatcaccta cttttatatc tacagctggt gttccttcac caggagtaaa agtctttgtg
     5341 tatttctgtg ttttagaaat ttctggtaca tatacaatag ctaaattttc ttttttcatt
     5401 tttttcaagt ttatatttcc acttactaag tatttttcta atgactttat catctcatca
     5461 ttataacctt ttagcttttg ctttagtgta tatttgccag tagtcttatt ttttatgaac
     5521 agaggattta gcttataata aggagttgaa tttatagctt cgtagtaatc taatctattt
     5581 attttattta cctctattct tgtgtttaag atactagcag ttttgacttt gtcaattcca
     5641 tctatatttt ttattttatc tatctgatta tcattaaacc cttttatatc tttaaaagaa
     5701 gtattgttac caatttcatt gagataaaca tttgatagaa taaaatctgc attcatatat
     5761 gtttgttctt gagtagattt gttttgcaca tctaaaaaag aatatttata attgtctttt
     5821 atgacgatta tacctcctat actcatagat aatacaatta taatgaaccc ctttttattt
     5881 ctaaagatgt ttttcgcaga tatagatttt gttactgaca tatttaaagt taattttgat
     5941 attaaataat taactttggt tacattttta tcagctccaa aagtttttct gatagcatca
     6001 ataggagaaa ttcttcttat ttttaagtat gtaaagaaac ttataattag tattattagt
     6061 attgtacatg caattgataa gagaattatt ttatctggaa taacaaaagg tgtaacattt
     6121 atatttcctt caaattgaat atttcctaca gacctattaa atatttgtgc acctcccata
     6181 cctatacata tacctatagg cattgctatt agagcaagta tgaaaagttc ataaagcata
     6241 agtttgaaaa tcctaaagtt ggtggaacca atagctctta agacgccata ttcctgtact
     6301 ctttggtata ttgatataac atagatacta tatattacaa taccagcaaa tagactcata
     6361 gcaattgcaa cgtatttact tgaattatct aaagtaccgt ttttcatagt agattctata
     6421 agcattgagt ttcttcctat acttttctca tctaacatag cattttttat tatattgtct
     6481 atgtttgtat ttatatcact gccttcatta aattcaatat aagttgtaaa atcattcagt
     6541 tctgattcat tgagattaga aaaaatttca cattgtccct tttttttctc tataaatcta
     6601 tcttcaagga ttccaacaac tttaaaagtt tctggatttt ctttttgata taatttaaaa
     6661 gtaaggtttt gatttatctc tggttttaag cccatactat ttaaaatcca tttctcgact
     6721 accacctcat tgctagcttt tggaaatcga ccttttataa gtttagaatg actagtcaaa
     6781 taatttttat ttgcatatag tatgtttata ggtaattttt cattaacatc tgtagacgca
     6841 tagtaagatg ttatacccag atttttaata tctttgctag attttatgga ctttaattga
     6901 tttttcttta tatttttaaa gtatacatgg tcagttccaa gctctctttt caatctatct
     6961 acatctgctt gctgagcact tcttgagagg gtaccaatac caacaacgag tgatgtagca
     7021 agaattatac tcacaacaat tgctaaagac ctagctttat aactttttat ataccttagt
     7081 actattttca aattatcttt catatttacc acttcctttc ttaactaaat caattatata
     7141 tttatctaaa atatatagca aagtaagtat tttcaagttt taagtagtta attgtacaaa
     7201 ttcatctgta tttttacaag tttaattaat ctatatgtaa attttaactt tttacataat
     7261 ttttttaaaa tgatataatc cctatataaa ttgtagaggg gagggaaatc atggctaaca
     7321 attttgtatt tcctatagta atactaactt tgtttatatt tagcaatctt ataatgaata
     7381 agtataaatt ttacaaagaa ttaga
//
LOCUS       DAJMZY010000147         7228 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.151, whole genome shotgun sequence.
ACCESSION   DAJMZY010000147 DAJMZY010000000
VERSION     DAJMZY010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7228)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7228)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7228
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.151"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            <1..631
                     /locus_tag="OE968_003464"
     CDS             <1..631
                     /locus_tag="OE968_003464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HCP7220697.1"
                     /translation="YVKEFYKTFDEAKGEYFDGFIITGAPVEQMEFEEVDYWNELEEI
                     MDYSKRKTKSTLYICWAAQASLYKYYNVKKLPLSQKCFGVFKHKVDKDSKIVDGFENE
                     FFAPHSRHTTVNIEALKENKELSIVSHSKEAGPYIITNSRDVFVMGHSEYDKYTLDKE
                     YKRDINKGDKISIPQNYYINDDPSEEPTVKWKKHSELLFRNWIKNYLIQ"
     gene            1119..1562
                     /locus_tag="OE968_003465"
     CDS             1119..1562
                     /locus_tag="OE968_003465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HCP7220698.1"
                     /translation="MDEMSFKKELLELTRDINMKFTTLLSDFYQPLGITAVQALILSE
                     LCEHGEKKISDLGKNLNMTNSNVSVICQRLEKNGFLNRIRDIEDQRIVKVKVTNKSLD
                     IQEHISSSIFDSYFENMTSEKLQDMEDIIEGLEKLNKLLTYIDCK"
     gene            1593..3410
                     /gene="ftsH"
                     /locus_tag="OE968_003466"
     CDS             1593..3410
                     /gene="ftsH"
                     /locus_tag="OE968_003466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HCP7220699.1"
                     /translation="MDEHKPQKRSALYYYTVIIIVVMFLNALIFPSLMDKKMVEIDYG
                     KFLTMLDTGKVKSVEIENNRIAINPSSSKDKNIYITGRMDDPELVDRLKNAKVEFTKV
                     IPKENSPLLSILLTWIIPIGILMLFGNLMMKSMQKRMGGNAMQFGKSNAKMYVSAQSG
                     KRFNDVAGQDEAKEALTEIVDFLHNPEKYKKIGAQMPKGALLVGPPGTGKTLLAKAVA
                     GEANVPFFSISGSEFVEMFVGMGASRIRDLFKQAKEKAPCIVFIDEIDTIGKKRDNGS
                     GLGGNDEREQTLNQLLSEMDGFDGGIGVVILAATNRPDSLDKALLRPGRFDRRIPVEL
                     PDLGGREAILKVHAQNVNVSSDIDYNAIARSTSGASGAELANIVNEAALLAVKSGRDI
                     VEQQDFDESVETVIAGYQRKGAVISDKEKKIIAYHEIGHALVAAMQKHSAPVHKITII
                     PRTSGALGYTMQVAEDESVLMSKEEAIDKITTFTGGRAAEEVIFNTCTSGASNDIEQA
                     TKIARAMVTRLGMSEEFDMVALETVSNQYLGGDTSLACSSDTAAKIDEEVFKIVKACH
                     KNAIEILENNIDKLHELANYLLEKETITGDEFMEILNLN"
     gene            3588..6290
                     /locus_tag="OE968_003467"
     CDS             3588..6290
                     /locus_tag="OE968_003467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase KdpD"
                     /protein_id="HCP7220700.1"
                     /translation="MDRPNPDILLEKIKNEEEKLSRGQLKIFFGYAAGVGKTYSMLES
                     AQNLKKVGVDVVVGYIEPHTRPETLALLDGLEILPVKEIEYKSIKLKEFDLDAALARK
                     PEVILVDEFAHSNVAGLRHTKRWQDIEELLLAGINVYTTVNVQHLESLNDIVEIITNV
                     SVKETIPDKFLDTNTQLELIDVEPDVLLERFNEGKIYKKEQATRAKNNFFIKDNLVAL
                     REIALRKTAERVNKEVQMTRLSKGDVTVIPTSDTLLACISPSPSSAKVIRTASRISDS
                     TFAKWIALYVETPNTARLPFDEQKQLQNNLKLAKKLGGEIIVLHGENIIEQILRIAKL
                     RNVTKIVIGRNHSSNKRFSKRFKKDIVDKLIDEVDYIDIHIIPYKFASDVKYKPKKDK
                     SSIKSKFKISKVDFIKLIFITLMISILAYAVQSMGFIRENILLIYMLGVVLVSMWTKG
                     YSTGIISSVFNIVLLNYFFTAPLYTLSIADSNYIVTLVVFSIVGIITSTLTSKIQHEA
                     ETAAKREENTKMIYQIIKGFLRLSNKDDIVNKGIELLSLSLSRDVICYLNVDKHNKSK
                     LYKKNTNNKDKNDLDSEDEKAVASWVLSNSTVAGNDTDTLPGSKGYYIPIVGMNLTLG
                     VVGISCIDSKLDTEDISLIETIIAQMAIALDREILSEAKENTNLEIERERLRSNLLRA
                     VSHDLRTPLAGISGAVSTIIKNKGTIGQDIIDELLSGVYEDTQWLIRLVENLLSMTKI
                     DEGKLEVKKHSELVEEIISEALQKIKKRIENALIDINIPEQILFVPMDAKLIEQVLIN
                     LIDNSLKYSKEDCKIEINVYEKDDYVWFEVSDNGPGISKELKKHIFDRFFTGEEGAKD
                     SRKGVGLGLSICKSIIQAHKGEIMVENNKDKGSTFKFSLPKENE"
     gene            6324..7022
                     /locus_tag="OE968_003468"
     CDS             6324..7022
                     /locus_tag="OE968_003468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCP7220701.1"
                     /translation="MSKKLILLVEDDKTIRKFISTALLTQDYDVKEAITGKEGISIAV
                     SYSPDVVLLDLGLEDMDGIEVIKAIRQFSNIPIIVVSAREQDRDKVEVFDAGADDYLT
                     KPFSIVELLARVRVAFRHSQVEAQQKDDVKSTFEVDKLLIDFDKRKVIVDDVEVHLTP
                     IEYNILSLLAKYHGKVLTHNFIIKEIWGSVIGNETKSLRVFMATLRRKIEKQPANPRY
                     IITEVGVGYRLNDE"
BASE COUNT         2868 a          793 c         1305 g         2262 t
ORIGIN      
        1 atatgttaaa gaattttata aaacatttga tgaagccaaa ggagagtatt ttgatggctt
       61 tataataaca ggagctccag ttgaacaaat ggagtttgaa gaagttgatt attggaatga
      121 actagaagaa attatggatt attctaagag aaaaactaaa tctacattat atatatgttg
      181 ggcagctcaa gcaagtcttt acaaatacta caatgtaaaa aaacttccac taagtcaaaa
      241 atgttttgga gtatttaagc ataaggtaga taaagatagt aaaatagtag atggatttga
      301 aaatgaattt tttgctccac attcaagaca tactactgta aatattgaag ctttgaaaga
      361 gaataaagag ttgagcattg tgagtcattc taaagaagct ggtccctata taattacaaa
      421 ttcaagagat gtgttcgtaa tgggtcatag cgagtatgac aaatacactc ttgataaaga
      481 atataagagg gatataaata aaggagataa aatatctata cctcaaaatt actatattaa
      541 tgatgaccct tcagaagagc caactgtaaa atggaaaaaa cattcagaat tgttgtttag
      601 aaattggata aaaaactatt tgatacaata aattttaaga gtatataaat gttaactaaa
      661 aaaatataga aatttatagg tataaagtta atcttaatga tactttatac cttatttttt
      721 taaaatttga ccttataata gtagttttat attttaagaa aatcacttta ggtgtatgta
      781 gatagaggtg gctttaattt tatatatggt gcgataatgg gagactaaac ctttatagta
      841 tcaataaatt tgtattttaa cttttaaaag agattaaaaa gggagaaatc agtgtaaaat
      901 atatatagat tttttattaa attttattaa aaatatcctg tataaaatta aatatcaata
      961 agataacaaa atttcaattg aagttacaat attgtaattg acaataaata cttaatacta
     1021 taatatttaa tacattaaac attatagtgt taagtattta ttacagtatg cacttcagcc
     1081 taaatttgaa ataaagtatt ttcgtaggga gcgtttgtat ggatgagatg agttttaaga
     1141 aagagctact agagttgact agagatataa atatgaaatt tacaacttta ttaagtgatt
     1201 tttatcagcc acttggtatt acagcagtgc aagctttgat tttatctgag ttatgtgaac
     1261 atggagagaa aaaaataagc gatttaggga agaacttaaa catgacaaat agtaatgtat
     1321 cagtaatctg tcaaaggctt gaaaaaaatg gctttttaaa tcgcataaga gatatagaag
     1381 accaacgaat tgtaaaagta aaagttacaa ataaatcatt ggatatacaa gaacatattt
     1441 caagtagtat ttttgatagt tattttgaaa atatgaccag tgaaaaattg caagatatgg
     1501 aagatataat agaaggttta gagaaattaa ataaactttt aacttacatt gattgcaaat
     1561 aacataaaaa taatttaaag gagaataaaa ttatggatga acataaaccc caaaaaaggt
     1621 cagcactcta ttattataca gttataataa tagtagtaat gtttttaaat gctttaatat
     1681 ttccaagttt aatggataaa aaaatggttg agattgacta tggaaagttt ctcacaatgt
     1741 tggatacagg aaaggttaaa tctgttgaga tagaaaataa tagaatagca ataaatccat
     1801 ctagtagcaa ggataagaat atatacataa ctggtagaat ggatgaccca gaattggtag
     1861 atagactaaa aaatgcaaaa gtagaattta ctaaggttat tcctaaggaa aattcacctc
     1921 ttttaagtat tttacttaca tggataatac ctataggtat tcttatgcta tttggtaact
     1981 taatgatgaa gtctatgcaa aagcgaatgg gtggtaatgc tatgcaattt ggaaaaagca
     2041 acgccaaaat gtatgtatct gctcaaagtg gaaaaagatt taatgatgta gctggtcaag
     2101 atgaggcaaa agaagcttta actgaaatag tagatttctt acacaatcca gaaaagtata
     2161 aaaagatagg agcacaaatg cctaaaggag cacttttagt aggacctcca ggtacaggaa
     2221 aaacactcct tgcaaaagct gtagcaggtg aagcaaatgt accatttttc tcaatatctg
     2281 gttctgagtt tgttgagatg tttgtaggaa tgggagcttc taggattcgt gatttattta
     2341 aacaagcaaa agaaaaagct ccatgtatag tgtttataga tgagattgat actattggta
     2401 aaaagcgtga taatggaagt ggattaggtg gaaatgatga acgtgaacaa actttaaatc
     2461 agttgttaag tgagatggat ggttttgatg gtggaattgg agtagtaata cttgctgcta
     2521 caaatagacc tgacagtctt gacaaagcat tacttcgtcc aggaagattt gatagacgta
     2581 taccagttga acttccagac cttggaggac gtgaagctat attaaaggta catgctcaaa
     2641 atgtaaatgt aagctcagat atagattata atgcaattgc aaggtctaca tcaggagcat
     2701 caggtgcaga acttgcaaat attgtaaacg aagcagcact tttagcagtt aagtctggca
     2761 gagatatagt agaacaacag gattttgatg aatctgttga aactgtaatt gctgggtatc
     2821 aacgtaaagg agctgtaatt tcagataagg aaaagaaaat tatagcatat catgaaatag
     2881 gtcatgcact tgttgctgct atgcaaaaac attctgcacc tgtccataag attactataa
     2941 tacctagaac ttcaggagca ttgggatata ctatgcaagt tgctgaagat gagagtgtac
     3001 ttatgtctaa agaagaagca attgataaaa taactacttt tacaggtggt cgtgctgctg
     3061 aagaggttat ctttaacact tgtacatcag gagcatcaaa tgatatagaa caagctacta
     3121 aaattgcaag agctatggtt actcgccttg gtatgagtga agagtttgat atggtcgctc
     3181 ttgaaactgt aagcaatcaa tatttaggag gagatacttc tcttgcttgt tcttccgaca
     3241 ctgctgctaa aatagatgaa gaggtattta aaatagtaaa ggcttgtcac aaaaatgcaa
     3301 ttgaaatctt agaaaataat attgataaat tgcatgaact tgctaattat ttattagaaa
     3361 aagaaactat tacaggtgat gagtttatgg aaatacttaa cttaaactaa aatgattata
     3421 cacaagataa aaatgcctat tgttaggcat ttttatttta caactaaatt ttttaaattc
     3481 atatttaaat ctttacataa tcttaatcat taaaaataca tcttaactac aattttatat
     3541 cggaattgat attataatag taatgaatgg tgtaaggagg ttttttaatg gatagaccta
     3601 atcctgatat tctattagaa aaaattaaaa atgaagaaga aaaactaagt agaggtcaat
     3661 taaaaatatt ctttggttat gcagctggag taggaaaaac ctactctatg ttggaatctg
     3721 cacaaaattt aaaaaaagtg ggtgtagatg tagtagttgg atatattgaa ccacacacta
     3781 gaccagaaac attggcttta cttgatggct tggaaattct tcctgtaaag gagatagaat
     3841 ataaatctat aaaactaaaa gaatttgatt tagatgctgc tttagcaaga aaaccagaag
     3901 ttatattagt agatgaattt gcccattcta atgttgctgg gttaaggcat acaaaaagat
     3961 ggcaagatat agaagaattg ctgttagcag gcataaatgt ctacactact gtaaatgtac
     4021 aacatttaga aagtctaaat gacattgttg agataattac aaacgtatca gttaaagaga
     4081 ctataccaga taagtttttg gatacaaata cacagttaga acttatagat gttgaacctg
     4141 atgtacttct tgaaaggttc aatgaaggta agatatataa gaaagaacaa gctactagag
     4201 caaaaaataa tttttttata aaagataacc tggttgcact tagagaaatc gcacttagaa
     4261 aaactgcaga gagagttaat aaagaagttc aaatgaccag actatcaaag ggtgatgtaa
     4321 ctgtaatacc tacatcagat acacttcttg catgtataag tccatctcca tcttcagcaa
     4381 aagttattag aactgcatcc agaatatcag acagtacatt tgcaaaatgg atagctttat
     4441 atgttgaaac tccaaacaca gcaagacttc catttgatga acaaaaacaa ctacaaaata
     4501 acctaaaatt agctaagaaa ttaggtggag aaataattgt tttacatggt gaaaatataa
     4561 tagagcaaat acttagaatt gcaaagctga gaaatgtaac aaaaattgta ataggtagaa
     4621 atcattcaag taataaaaga tttagtaaaa gatttaaaaa agatatagtt gacaaattaa
     4681 ttgatgaagt tgattatata gatatacata taattccata taaatttgcc tcagatgtta
     4741 aatacaaacc taaaaaggat aaatcatcaa taaaatctaa atttaaaatt agcaaagttg
     4801 attttataaa acttatattt attactttga tgataagtat tttagcatat gcagtacaaa
     4861 gcatgggatt tataagagaa aatatattgt taatatatat gttgggtgta gttttagttt
     4921 ctatgtggac taaagggtat agtacaggta taataagttc tgtatttaat atagttcttt
     4981 taaattattt tttcacagca ccattatata cattatctat agcagattca aactatatag
     5041 taacactggt tgtattctca atagtaggta taataactag cactcttacg tctaagatac
     5101 agcatgaagc agaaactgct gctaaaagag aagaaaatac aaaaatgata tatcaaataa
     5161 ttaagggatt tttaagatta tcaaataaag atgatatagt aaacaaaggt atagaacttt
     5221 tgtctcttag cttaagtaga gatgtaattt gttatttaaa tgtagataag cataataaat
     5281 caaagcttta caaaaaaaat actaataata aggataaaaa tgatttggat agtgaagatg
     5341 aaaaagctgt tgcaagttgg gttttatcca attcaacagt agcaggaaat gacacggata
     5401 cacttcctgg ttcaaaggga tactatatac caattgtagg aatgaattta actttaggag
     5461 tagtgggaat atcatgtatt gattcaaaat tggatacaga agatataagc ttaattgaaa
     5521 caataattgc tcaaatggca atagcgcttg atagagaaat cttgtcagaa gctaaagaaa
     5581 ataccaatct tgagattgaa agggaaagat taagaagtaa tcttttaaga gcagtttcgc
     5641 atgaccttag aactccacta gcaggaatat ctggtgcagt aagtacaatt ataaaaaaca
     5701 agggtactat aggtcaagat ataatagatg aattacttag tggtgtatat gaagatactc
     5761 agtggttaat aagacttgtt gaaaatttac ttagtatgac caagatagat gaagggaaat
     5821 tggaagttaa aaaacattct gaactggttg aggaaattat atcagaagcg ttacaaaaaa
     5881 taaaaaaaag aattgaaaat gcacttatag atattaatat accagaacag atattatttg
     5941 ttcctatgga tgcaaaatta atagaacaag ttttaattaa tttaatagat aattctttga
     6001 aatattcaaa ggaagattgt aagatagaga taaatgtata tgagaaagat gattatgttt
     6061 ggtttgaagt atctgataat ggtcctggta tatcaaagga acttaaaaag catatctttg
     6121 acagattttt tactggagaa gaaggagcta aagattccag aaagggtgtt ggacttggat
     6181 tatcaatttg taaatctata attcaagctc ataaaggtga aattatggta gaaaacaata
     6241 aagataaggg ttcaactttt aagtttagtt tgcctaagga aaatgaatag ttttaaattt
     6301 taaaattagt tttggaggaa gaaatgagta aaaaacttat attgttagta gaggatgata
     6361 agacaataag aaaatttata tctactgcac ttttaacaca ggattatgat gtcaaggagg
     6421 ctataactgg aaaagaaggt atatctatag ctgtctcata ttctccagat gttgttcttt
     6481 tagatttagg cttagaagat atggatggaa tagaggtaat aaaagctatc agacaatttt
     6541 caaatatacc aataattgta gtttcagcta gagagcaaga tagagacaag gtagaagtat
     6601 ttgatgcagg ggcagatgat tacttaacaa aaccattctc catagtagag ttattagcaa
     6661 gagtaagagt agcatttaga cattcacaag tagaagctca acaaaaagat gatgttaaat
     6721 ctacgtttga agtagataaa ttattgattg attttgataa aagaaaagtt attgttgatg
     6781 atgttgaagt ccatttgaca cctattgaat ataatattct ttcattactt gcaaagtatc
     6841 atggaaaagt gcttactcat aattttataa taaaagaaat atggggtagt gttataggga
     6901 atgagactaa gtctttaagg gtctttatgg caacgttaag acgaaaaata gaaaaacaac
     6961 ctgcaaaccc aagatatata attacagaag ttggtgtagg atacagatta aatgatgaat
     7021 agttgtaata tattaattat tagattatgt gcttattaat atatattaaa attatatagt
     7081 ttagttaaaa taagaatgaa gtgtatgtgc ttgttgtcag tttagcacat gcattttatt
     7141 ttttagcttt tttagtatca ataatttttt agtatcaata atatgaaata tgttttaaaa
     7201 taagtatata gtgtaatctg taataaaa
//
LOCUS       DAJMZY010000148         7078 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.152, whole genome shotgun sequence.
ACCESSION   DAJMZY010000148 DAJMZY010000000
VERSION     DAJMZY010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7078)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7078)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7078
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.152"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            complement(<1..241)
                     /locus_tag="OE968_003469"
     CDS             complement(<1..241)
                     /locus_tag="OE968_003469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCP7220702.1"
                     /translation="MIAVKKAYKFRMYPNKKQQELINKTFGCCRFVYNKYLAKRIDVY
                     KNDKETFTYKQCSSDLTNLKKELKWLKEPDKFSLQN"
     gene            complement(889..1296)
                     /locus_tag="OE968_003470"
     CDS             complement(889..1296)
                     /locus_tag="OE968_003470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220703.1"
                     /translation="MSKVAKATFYLMIVTIISKILGMGRELVLSSIYGTGLYTESYLT
                     AMNIPNIIFAAIGTAIVTTFIPMYQDISSKQGEKQALKFLNNVLNIIVGICIVVAILG
                     VIFSKQLVSIFAIGFEGERFLLTVKFTKILIKK"
     gene            complement(1770..2654)
                     /locus_tag="OE968_003471"
     CDS             complement(1770..2654)
                     /locus_tag="OE968_003471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HCP7220704.1"
                     /translation="MDTKKENNYENYICVGSSNVSNAMKMYLKEIEEYKMLSAGEEVE
                     LAKEIINSSSVAKEKFINSNYRLVVSIAKRYKRDSIDMLDLIQAGNIGLIKAVEKYDY
                     KKGYKFSTYATWWIKQSITRYIDDCENTIRIPIHLHQRINFVKKKKQELLNVLLREPT
                     IDEIADACGLEVDKVLELLRRDKNVVSLDTPLKEDEDSSLVEFIPSDADFKDVVIHEV
                     EQHNLKEKIEELLTGLGEQEQQVLRMRFGIDDDDPKTLEQIGKVFGVTRERIRQIEAK
                     AIRKLRHPSKLKQLKHFY"
     gene            complement(2945..3421)
                     /locus_tag="OE968_003472"
     CDS             complement(2945..3421)
                     /locus_tag="OE968_003472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction enzyme HsdR N-terminal
                     domain-containing protein"
                     /protein_id="HCP7220705.1"
                     /translation="MSKELVKDRVIKYLIEDLLVPQDMIDTNVELAEFEEGAEGILDI
                     VVNVKDEEDYYAPVMIVQCLDEDVELEGEVLQKQIEFLEEVDNITMSGRLVLTNGDAM
                     MYADWRGEEYDTEAALPTYDIMVKEFHEMEQQVKDLEEHHHHDENCGCGCNHHHEN"
     gene            3687..4862
                     /locus_tag="OE968_003473"
     CDS             3687..4862
                     /locus_tag="OE968_003473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HCP7220706.1"
                     /translation="MKFKKQISSIVVSTMLVLGSMNLSYADGTNVVTLGANLSESQKQ
                     QMLNYFGVKKDQVLVLDVTNAEERQYLQGVATEGQLGKVTISCSYVEPTKKGNGINVK
                     TANLTWVTSSMIASTLTTAGLEDANVIAAAPYPVSGTGALTGIMKAFEDASGKKLDET
                     KKEIASEELVVTGDLGDDIGQEKATGVMNDIKTEIVKNGTKDTNQIANTINNVVNNYN
                     ITITPEQKEQIKGVMKKIADQNYDYNSMKNTLDNVSDNVNEQLKKLGESVKGSGILDT
                     IGGWFSGIGDWFSGLFSGGDKKDLGILNNTNDESLGSDAVINSTEGVQINPQNNTNSN
                     NDSDTNSSKNDTSSNNENNDSSQTNENNTTNNSENQSNNNDSVGFFEKIKNWLSGLF"
     gene            complement(4943..5746)
                     /gene="proC"
                     /locus_tag="OE968_003474"
     CDS             complement(4943..5746)
                     /gene="proC"
                     /locus_tag="OE968_003474"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HCP7220707.1"
                     /translation="MKKIGFIGAGNMASAMIGGIVNSKLVEPNMVIASAYSQGTLDRI
                     DANFGINTTKDSKEVTRTSDIVIVAVKPDIYDDILEEIKDFIDDNKIIVTIAAGKSIK
                     DIESIIGEDKKIVRTMPNTPALVNEAMSSLSINKNINKEDLEAVTEVFNSFGNTEVVP
                     EYLIEAVIGASGSAPAYVFLFIEAIADAAVIAGMPRPQAYKFASQAVMGSAKMVLETG
                     KHPGELKDMVCSPGGTTIEAVKVLEEEGFRASVIKAICACIEKSKKMSE"
     gene            complement(5786..6370)
                     /locus_tag="OE968_003475"
     CDS             complement(5786..6370)
                     /locus_tag="OE968_003475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCP7220708.1"
                     /translation="MNKDIGAKIKQLRTQKQMTLKDMSEKTNLSIGFLSQLERGLTSV
                     ATDSLGKIASVLDVELTYFFMKPKEHKRAVLRSYEKEVFDVENSTFIHYHLSSSLKEK
                     TMLPRLIEILPSKSSEEICCYVHEGEEFVYVLEGTLTVFLGDEQIEMYPGDTIHYNSE
                     KNNHNWVNYTNKVVKILVVSIPNPFEKSDAVKEA"
BASE COUNT         2343 a         1175 c          774 g         2786 t
ORIGIN      
        1 cgttttgtag tgaaaatttg tcaggttctt taagccattt taattctttt tttaaattgg
       61 tcaaatcaga actacactgt ttataagtaa aagtttcttt atcgttttta taaacatcta
      121 ttcttttagc aagatactta ttatatacaa atctacaaca tccaaaagtt ttgttaatta
      181 actcttgttg ttttttattt ggatacattc taaacttata agcttttttc actgctatca
      241 cctcacttta attgtttttt gatacacttt ttaatgattt tatcacattt tatcacattt
      301 aatatattat ataatgctgt ggtaaacaat ttattaatca cctataataa tgttaacaaa
      361 tgtaattatt taaaacaatt atttagaagg ttttatattt aattttaaat aacatattta
      421 agaaccgtaa gtcttaactt ttatcatttt gaggttgtcg ttcacataag ttcgctacta
      481 cctatgcagt tctcttatga acttcttaca ttttcatgta agcacagact atatcttatc
      541 cttcagcatt atccgttaag gtctacccac ttccactacc aatagcttgt agtgtacttc
      601 cctcaagagg aatagtcgtt gaagtttctc ctgttcggag tttacctgct gattgcccat
      661 tttaaagtac ttaggattta accttatacc atctaaccaa ttttttctac tttcgtaact
      721 ttcacactta ggtttatttc atccttatgt tttagtttga ttagctttag gggtttccag
      781 caattcaagt agtattggat aggttctatc ctatctctac atataggttt ccctatatgc
      841 tgactatttt agctactaac tcatgactaa agtcacgagt gtgtgtagct attttttaat
      901 caatatttta gtaaatttta cggtaagtaa aaacctctct ccttcaaatc ctatagcaaa
      961 tatacttaca agttgctttg agaaaataac tcctaatata gctacaacta tgcatatacc
     1021 aactattata tttaaaacat tgtttaaaaa ctttagtgct tgcttttcac cttgtttact
     1081 acttatatct tgatacattg gaataaaagt agtaactata gcagtaccta ttgctgcaaa
     1141 tataatattt ggtatattca tagctgttaa ataactctct gtatataagc ctgtaccata
     1201 aattgatgat aatactaatt ctctacccat tccaagaatc ttagagatta tagtaactat
     1261 catcaaataa aaagttgctt tagctacctt gctcatttta tcactccact tctaacatac
     1321 ctctttttaa tcaagtaaaa tttagctcat tagatataat tctatcaact aatttgcctt
     1381 gcttagccct atcaaaatat aattaacacc tatttcttaa tatatcacaa actacattat
     1441 tcttcatatt tttttatttc tccaataagt tttacatttt tcctatataa attgtatagc
     1501 ttcaattata ttcaaagaaa tggagttgct acccgataac tttaaaagta aaaaacagat
     1561 tttattatct ttttaaacta tattctaaca tattttgtcc atattgagaa attttactaa
     1621 actattatgt actttattaa ataaataaaa taacagcaca cctataaaat acaagtgtgc
     1681 tgttcataaa cagattttat aaaaaaataa ttcctaagta gagattaaca tgctttctca
     1741 tactctcata tataatgtgt ctaaaaatat taataaaaat gttttaattg ttttaactta
     1801 cttggatgtc ttaattttct tattgcttta gcttctatct gtcttattcg ttctctggta
     1861 actccaaata cctttccaat ctgttctagt gttttagggt catcatcatc aattccaaat
     1921 ctcattctta aaacttgctg ttcttgctct ccaagacctg taagtagttc ttctatcttt
     1981 tcttttaaat tatgctgttc aacttcgtgt attacaacat ctttaaaatc agcatctgat
     2041 ggtataaatt caactaaact actatcctca tcttctttta atggagtatc caaagataca
     2101 acatttttat ctcttcttaa taattccaac actttgtcaa cttctaagcc acatgcatct
     2161 gcaatctcat ctatagttgg ctctcttaat aatacattta aaagttcttg tttctttttc
     2221 tttacaaaat ttattctctg atgaagatgt ataggtatcc taatagtatt ttcgcaatcg
     2281 tcgatatatc ttgttatact ttgttttatc caccaagttg cataagtgct aaatttgtat
     2341 ccttttttat aatcgtactt ttctacagct tttataagtc ctatatttcc tgcttgaatt
     2401 aaatccaaca tatcaatact atctctttta tatctctttg ctatgctcac taccaaccta
     2461 taatttgaat ttataaattt ttcttttgct actgaagatg agttgattat ttccttagcc
     2521 agctctacct cttctcctgc tgacaacatt ttgtattcct ctatttcctt taaatacatt
     2581 ttcatcgcat tcgatacatt tgatgaaccc acacaaatat aattttcata attattttct
     2641 tttttagtat ccataatcaa accccttcta ttcatagaat ttgctaaaac aaaaataaat
     2701 aatttaaacc tacataatct acaattacat aatatcccat tctttaaatg aattgttttg
     2761 tatattatgt atacaaattt ataaaaacta tacctataat attattctac ttctaacagc
     2821 aatatcctcc ttatatatat aatttatttt attatatgtt gttatattct tagttttttg
     2881 aatgatatat gtctaaaaaa agactgttta ctaaacagtc tttttttata tatatgctca
     2941 atatttaatt ttcatgatga tgattacatc cacatccaca attttcatca tggtgatgat
     3001 gttcttctaa atcttttacc tgttgttcca tttcatgaaa ctcttttacc attatatcat
     3061 aagttggaag agctgcctca gtatcgtatt cttcccctct ccaatcagcg tacatcatag
     3121 catctccatt agttaaaacc aatctacctg acatagttat attatccact tcttctaaaa
     3181 attctatttg tttttgtaaa acttctcctt ctaactccac atcttcatct aaacattgca
     3241 ctatcattac aggtgcataa taatcttctt catctttaac atttacaaca atatctaaaa
     3301 ttccttctgc accttcttca aattctgcca actcaacatt tgtatcaatc atatcttgag
     3361 gtactaataa atcttctatt aaatatttta ttactctatc ttttactaat tcttttgaca
     3421 tttatttttc tccttccgat tctataacat tatcataatc atttctatat tatagtatac
     3481 tacattaatt gttttttcaa tctcttacaa aaattatttt ttattatctt ccttatattc
     3541 ccttttttat tacaaagttg taatcgcatt gatttaaaaa atagtttata tttagtataa
     3601 tagaaatgta gcacatattt ttattcaata tattaataaa aaaatatatt gaaaatgtaa
     3661 tgtatgttaa atctaggagg aatattatga agtttaaaaa acaaattagt tctattgttg
     3721 tgtctactat gcttgtactt gggagtatga acctttctta tgcagacggt acaaatgtag
     3781 ttacacttgg agctaactta tcagagtctc aaaagcagca aatgcttaat tactttggag
     3841 taaaaaaaga ccaagtctta gttttagatg taacaaatgc agaagaaaga cagtatttac
     3901 aaggtgttgc aacagagggt caacttggaa aagttactat ctcttgctca tacgttgaac
     3961 ctactaaaaa aggaaatgga attaatgtta aaacagcaaa cttaacttgg gtaactagtt
     4021 caatgattgc ttcaaccctt acaacagctg gtcttgaaga tgcaaatgtt attgctgctg
     4081 ctccatatcc tgtaagtggt actggagcat tgacaggaat catgaaagca tttgaggatg
     4141 cttcaggaaa gaaacttgat gaaactaaga aagaaattgc ttctgaagaa ttggtagtta
     4201 caggtgactt aggagatgat atagggcaag aaaaagcaac aggtgtaatg aatgatataa
     4261 aaacagaaat tgtaaaaaat ggtacaaaag ataccaatca aatagcaaat acaataaata
     4321 atgttgtaaa taattacaat attactatta caccagaaca aaaagaacaa attaaaggtg
     4381 taatgaaaaa aatagctgac caaaattacg attacaatag catgaaaaat acactagata
     4441 atgtatcaga taatgtaaat gaacaattaa agaaattagg tgaaagtgtt aagggttctg
     4501 gtatactaga tactattggt ggatggttta gtggaatagg agactggttc tctggtttat
     4561 tctcaggcgg agataaaaaa gatttgggaa tcttaaataa tactaatgat gagtctcttg
     4621 gctctgatgc tgtaataaat tctacagaag gtgttcaaat aaatccacaa aataatacta
     4681 attctaacaa tgatagtgat acaaatagct caaaaaatga tacttcaagt aataatgaaa
     4741 ataacgatag ttctcaaaca aatgaaaaca acacaacaaa taattcagaa aatcaatcaa
     4801 ataataatga ctcagttggt ttctttgaaa aaataaaaaa ttggctttca ggcttatttt
     4861 agaaattaaa caaataaaaa gaattgccta aaatggaaat tttctataaa aggcaattct
     4921 ctttatttac aataaatttt tattactcac tcattttttt agatttttct atacatgcac
     4981 atattgcttt tatcacagaa gctctaaaac cttcttcttc aagtacttta actgcttcta
     5041 tagtagttcc accaggtgaa cataccatat cttttaattc accaggatgt tttcctgtct
     5101 caagtaccat ttttgcagaa cccataacag cctgtgatgc aaacttatat gcttgtggtc
     5161 ttggcattcc tgcaattact gctgcatctg ctatagcttc tataaataaa aatacatatg
     5221 ctggtgcaga accacttgca ccaattacag cttctataag atactctggt actacctcag
     5281 tatttccaaa agaattaaat acttctgtaa ctgcttctaa gtcttctttg tttatatttt
     5341 tatttataga aagagaagac atggcttcat ttacaagagc tggagtattt ggcatagttc
     5401 taactatttt tttatcttct cctataatag actctatatc ttttatagat tttcctgctg
     5461 ctattgtaac tataatttta ttgtcatcta taaagtcttt tatctcttcc aaaatatcat
     5521 catatatatc tggtttaaca gctacaatta ctatatcaga ggttctagtt acttccttcg
     5581 agtcttttgt agtatttatt ccaaaatttg catctattct atcaagagtt ccttgactat
     5641 atgctgatgc tataaccata ttaggttcaa ctaattttga atttactatt ccccctatca
     5701 tagcgcttgc catatttcct gcacctatga atccaatttt tttcacttta gtacctcctt
     5761 attgactaat agtaatcgtt aaaatttaag cttctttaac tgcatcagac ttttcaaatg
     5821 gatttggtat acttactacc aaaattttca ctaccttatt agtatagttg acccaattat
     5881 gattgttctt ttcactatta tagtgtattg tgtctcctgg atacatttct atttgttcat
     5941 ctcccaaaaa cactgtaaga gtaccctcta atacatacac aaattcctca ccttcatgta
     6001 cgtaacaaca aatttcctca ctactcttac ttggaagaat ttcaattaat cttggtagca
     6061 ttgttttttc ctttaaacta gatgataaat gataatgtat aaatgttgag ttttctacat
     6121 caaatacttc tttttcataa cttcttaata cagctctttt atgctctttt ggcttcataa
     6181 aaaagtaagt taattctaca tctagtacac ttgctatttt tcctaaggaa tctgttgcca
     6241 cacttgttaa tcctctttca agttgtgata aaaaaccaat tgacaagttt gttttttcac
     6301 tcatatcctt cagcgtcatt tgcttttgag ttctgagttg ctttattttt gctcctatgt
     6361 ccttattcaa aaccatcacc cctaaataat tttaattttt tcataatata aatacaaaaa
     6421 tataaatata ggtactgaac ctatctttat ttcatttaaa aaaattttta taagtattac
     6481 tataatttat caatcttttt ttgtctacat ttttacgatt atttacgatt tatttttcac
     6541 atatgtatat ttaatcttgc caactaaaga tacatttttt ataagcattt actctttata
     6601 taataaaact taagttgttc atgagtcttc ttctggttta attattaaaa tttcaaatta
     6661 tattattatt tctacacatt attacatcct ttagtacaat tataacataa ttttacaatt
     6721 taatgatatc tattcaatgt ctttttttac tctacaacat attttatttt agagtttaat
     6781 actatatata ttttttatat acagccttgt cattttttag attgtcaaga gttattgaag
     6841 tattttatgt agatttagat tttattttct aatttctcat ttaacaagaa ttgcttatga
     6901 taaaaaataa tatcatctca ataagattct tgtaaatata tctatattct aaatataatt
     6961 tctttttttg tcaaaatttc ttcattcttt aataattaat ttattactta taaaataaac
     7021 taattatcta tacaaatttt ataattttta ataaaataca caaaaaaatt aattttta
//
LOCUS       DAJMZY010000149         7053 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.153, whole genome shotgun sequence.
ACCESSION   DAJMZY010000149 DAJMZY010000000
VERSION     DAJMZY010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7053)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7053)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7053
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.153"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            <1..497
                     /locus_tag="OE968_003476"
     CDS             <1..497
                     /locus_tag="OE968_003476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HCP7220709.1"
                     /translation="NPTHSTNRIYDAVGIARCIRSQAGGGGAKTGLYFIDLNKNSKVT
                     INARCLKAKYNAGVTNRNCDNSGVLVNAVLTPDRVNKRQNGRRIKESGEPMFTLTAQD
                     KHGILKNGDIRRLTPKECFRLQGFPDKYYERAASVCSDSQLYKQAGNAVTANVVYEIA
                     KRMG"
     gene            576..797
                     /locus_tag="OE968_003477"
     CDS             576..797
                     /locus_tag="OE968_003477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220710.1"
                     /translation="MSKYVLRWQKGLLLDERKINYSCGSKEMLKQKAELLAKDDKILL
                     VTIDKVEEVIKDTRSQKMTEYYCDGGIEI"
     gene            794..1798
                     /locus_tag="OE968_003478"
     CDS             794..1798
                     /locus_tag="OE968_003478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HCP7220711.1"
                     /translation="MIIHKFIIHVLDKNSDTPILNDFEGRVSQDMDLFFQKKIKTVSR
                     AKDIRTAVFNDYSNNLIKKCCEQIIYDESSFLNNSKEIAAYLFDVMKLNATLESCDLA
                     ICLYSQKDEKKVAILKLDYNKSYTHSIEFKDDKFNIQMSKNEINIQETKTVKIAALVG
                     LSGMNDEYHLRVLDKDAEKEEANSKFITEFLNATKVKDDKYKTKMFKSTAENWITNAL
                     GNDIKQAEDVRSILNYTLKEKHEIDINNFVDKTIKDDKLKDSFKEHMEEKGLVEGFSI
                     DKKWVDKKLKKRNIKTDNGFEIKGNLTDFEDPMKYTVRQNQNGSIDIVIKNVTFYEEK
                     "
     gene            1880..2209
                     /locus_tag="OE968_003479"
     CDS             1880..2209
                     /locus_tag="OE968_003479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220712.1"
                     /translation="MKIFLLTILLIIICILANYVKNRIYKKSINNLKYKYSVGEKIIY
                     HQINCYYNRMVGCEILEKCYSTKFRKRNTPLYKVKAYVGDNDTTWVIPEWRIECLATT
                     YGEFPKY"
     gene            2246..2617
                     /locus_tag="OE968_003480"
     CDS             2246..2617
                     /locus_tag="OE968_003480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220713.1"
                     /translation="MFNIYKVKIKTKRTLEQVRNQSVDFEYSEKGLKNTLKYYNLIDD
                     LKVIVVKFGDEYCLANYNEEDRKIIMEAHYLLEQDEYTGCYINEYERFKKDWENGNCD
                     GEACMVFSDDEIEIIEKLREG"
     gene            2620..2760
                     /locus_tag="OE968_003481"
     CDS             2620..2760
                     /locus_tag="OE968_003481"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220714.1"
                     /translation="MNKRIKMKKRLIHKKCDERCVNYDFVISNNLITCNVCRMQIQRK
                     YG"
     gene            2875..3216
                     /locus_tag="OE968_003482"
     CDS             2875..3216
                     /locus_tag="OE968_003482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor-like protein"
                     /protein_id="HCP7220715.1"
                     /translation="MANIYCENYNCKNYFEDMCMLERIEINNFKECESYLEGKNELYE
                     LENGYTIHPKDLKMVKSKDYSVEVTHIPTGITVKCRSTNSILKNKNKCLEALEEELTK
                     INSHLELEDLR"
     gene            3342..3749
                     /locus_tag="OE968_003483"
     CDS             3342..3749
                     /locus_tag="OE968_003483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HCP7220716.1"
                     /translation="MKVFLVIDGEPVGKERPRFNLATKRTYTPQKTKDYEELIKWLYQ
                     SKVRHYFTGYIKMTLRCYYSIAKSNSKKIKEQKRNNVLRPNKKPDIDNVVKIIADSLN
                     EIAYKDDTQIVEVVASKYYSDKPRVEVILEDVI"
     gene            3851..4699
                     /locus_tag="OE968_003484"
     CDS             3851..4699
                     /locus_tag="OE968_003484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ORF6C domain-containing protein"
                     /protein_id="HCP7220717.1"
                     /translation="MNENINKEITVLGTLEIEGMKFHNIEGGFGEHKKAMLVKDIAEI
                     HNRESRQINELINKNRKRFKDGKDILDLLGVGLDDTKIKELGFTQQSINSYRGLKNKG
                     LLSGIYILSERGYAKLLKILEDDIAWELYEKLVDGYFSMRKELNNPLLSASKELQAIF
                     MLDKKQEVLETKIENVNEKLENFMDDAPLFNIECECIVKEVKRVATKSLGGHGSKAYK
                     NKSLRGKVYSDIYHQIKREFGVDSYKAIKRCQLDKVLEIVNSYKLPIVFEEEIRLLNS
                     QLSIVS"
     gene            4842..5330
                     /locus_tag="OE968_003485"
     CDS             4842..5330
                     /locus_tag="OE968_003485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220718.1"
                     /translation="MDNNINKKELFKKVEGRLHHYKFLSAEIKNLELDIESRENEIFG
                     CKAIGYGEKVSPTYAFNSTVENEIIKKERDIARLKKLKKDKEIEKKKIENALTCLDIR
                     EEHFFKLFYNSRMKNSMVYISLEMNSDRKTCRCVRERLVYKVMDMLYPRIKENELPLF
                     KN"
     gene            5912..6589
                     /locus_tag="OE968_003486"
     CDS             5912..6589
                     /locus_tag="OE968_003486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bro-N domain-containing protein"
                     /protein_id="HCP7220719.1"
                     /translation="MLKILQEKNVKVMWSKNGEEVWFNANDVGEELGIVNIRDTLRNI
                     DREYKKKFNESTVGDSYTRNFKDKLPNFGTTFVTEEAVYNMSFRSNKPEAKLFTKWVT
                     KTLKQIRIHGYYIATEKDQEWLDIRTEGKKVRKDFTDEIQEFVYYATSQGSNKPQMYY
                     KHFTELVRKKLGIPKGVKRDELNQSELFDIQALERIISMKLPKLIDKDMNYKEVYKKI
                     KELIEMI"
     gene            6652..>7053
                     /locus_tag="OE968_003487"
     CDS             6652..>7053
                     /locus_tag="OE968_003487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCP7220720.1"
                     /translation="MQDVKEKVKQDYIKGMKQKEISAKYDISLNTLKSWIKRYNWASE
                     KKKGAPKNKRGAPIGNKNATGPPGNKNAEKFGFFSKYLPEETRELIQEISIKDKFDIL
                     WEQITIQYAAIIRAQKIMYVKDKEEMIKELKK"
BASE COUNT         2965 a          701 c         1343 g         2044 t
ORIGIN      
        1 ataatccaac tcatagtaca aatagaattt atgatgcagt tggaattgct agatgtatta
       61 gaagtcaggc aggaggtgga ggtgctaaaa caggtctata ctttatagac ttaaataaaa
      121 actctaaagt aacaataaat gctagatgcc ttaaagcaaa atataatgca ggtgtgacaa
      181 atagaaattg tgataatagt ggagttttag ttaatgcagt tttaacgccc gatagggtaa
      241 ataaaagaca aaatggtcgt agaattaaag aaagcggaga accaatgttc acactaacag
      301 ctcaagataa acatggaatt ttgaaaaatg gagatataag aaggttaaca ccaaaggaat
      361 gctttaggtt gcaaggattt ccggataaat attacgaaag agcagcaagt gtatgctcag
      421 atagtcaact gtacaaacaa gcgggaaatg ctgttactgc aaatgttgta tatgaaatag
      481 caaaaagaat gggctaagag ttgcaaaatg tcttttagta tgagtattgt tgaagtgttt
      541 tgtaactctc aaaaatgaaa ataaggggtg aataaatgtc aaagtatgtg cttagatggc
      601 aaaaagggtt attgttggat gaacgtaaga taaattattc ttgtggaagt aaggaaatgt
      661 taaaacaaaa agcagaatta ttagctaaag atgacaagat actgcttgta acaatagata
      721 aagttgaaga agttataaag gatactagaa gtcaaaaaat gactgaatat tattgtgatg
      781 gaggaattga aatatgataa tacacaaatt tataatacat gttttagata agaatagcga
      841 tacaccaata ctaaatgact ttgagggtag ggttagtcaa gatatggatc tattttttca
      901 gaagaagatt aagacagtat caagagctaa agacattaga acagcagtat ttaatgacta
      961 tagtaacaat ttaattaaga agtgttgcga acaaattatt tatgatgaaa gttcattttt
     1021 aaataactct aaagagattg cagcttattt atttgatgtt atgaaattga atgctacatt
     1081 agaatcttgc gacttagcaa tttgtttata ctctcaaaaa gatgaaaaga aagttgctat
     1141 attaaagctt gattacaaca agtcatatac tcattcaatc gagtttaaag atgataaatt
     1201 taatatacaa atgtctaaaa atgaaattaa tatacaagag actaagacag taaaaattgc
     1261 tgctttggtt ggtttgagtg gaatgaatga cgaatatcat cttagggttt tagacaagga
     1321 tgcagaaaag gaagaagcta attctaagtt tattacagag tttctaaatg ctactaaagt
     1381 gaaagatgac aagtacaaga ctaagatgtt taaaagtaca gccgaaaatt ggataactaa
     1441 tgctcttgga aatgatataa aacaggcaga agatgtaaga agtatattaa attatacttt
     1501 gaaagaaaag catgaaattg atataaataa ttttgttgat aaaacaatta aagatgataa
     1561 gttaaaagat agttttaaag aacatatgga agaaaaaggt cttgttgaag gatttagtat
     1621 agataaaaaa tgggttgata aaaagcttaa aaagagaaat ataaaaactg acaatggctt
     1681 tgaaataaaa ggtaacttaa ctgattttga ggacccaatg aaatatacag taagacaaaa
     1741 tcaaaatggg tctatagata tagttattaa gaatgtaaca ttttatgagg aaaagtaggt
     1801 actcatgtga ctattggcta gagaaggaga agtaaataat aagaggatgt aaatttaaac
     1861 tagttaggag gaataactta tgaagatttt tttattgact atactgctaa taattatttg
     1921 tatattagca aattatgtga aaaatcgcat atataaaaaa tctataaata atctaaaata
     1981 taaatattct gtaggggaaa agattatata tcatcaaata aactgttact ataacagaat
     2041 ggttggttgt gaaattttag aaaaatgtta tagtacgaaa tttagaaaaa gaaatacccc
     2101 gctttataaa gtaaaagcat atgtaggtga taacgataca acatgggtta taccagagtg
     2161 gagaattgaa tgtcttgcta cgacttatgg agaatttcct aaatattaaa taataaaaat
     2221 tggctggaga aggagattgt aaattatgtt taacatctat aaagtgaaaa taaagactaa
     2281 aagaacattg gagcaggtaa gaaatcaaag cgtagacttt gagtattcag aaaaaggatt
     2341 aaaaaatact ctgaaatact ataacttgat tgatgattta aaagtaatag tagttaaatt
     2401 tggagatgaa tattgtctag ctaattacaa tgaagaagat agaaaaataa taatggaagc
     2461 acattatctt ttagagcagg atgaatatac tggatgttat ataaatgaat atgaacgatt
     2521 taaaaaagat tgggaaaatg gtaattgtga tggggaagcc tgtatggtat tttcagatga
     2581 tgaaattgag ataattgaga agctaaggga gggttaaata tgaataaaag aattaaaatg
     2641 aaaaaaagat taattcataa aaagtgtgat gaaagatgtg tcaactatga ctttgtaatt
     2701 agcaataacc ttataacttg taatgtgtgt aggatgcaaa tacaaagaaa atatggataa
     2761 agtatgtgaa gagaactata agaaattaag aagtaaatag aataaaatag tcaaggtaag
     2821 tttgtgaatg aaactagaat gttataggct tgacttataa aaggagtgcg ttaaatggct
     2881 aatatatatt gtgaaaatta taattgtaaa aactactttg aagatatgtg tatgcttgaa
     2941 agaattgaaa ttaataactt caaagaatgc gaaagctatc ttgaaggtaa aaatgagcta
     3001 tatgaattag aaaacggata tactatacat cctaaagatt tgaaaatggt gaaaagtaaa
     3061 gattattctg ttgaagttac tcatattcca actggtatta cagtaaaatg ccgttctaca
     3121 aatagtattt taaaaaataa aaataagtgt ttggaagctc tagaagaaga actaacaaaa
     3181 ataaactctc acttagagct agaagattta cgctaaatag gaagtgagct tatgaaacga
     3241 agaagatgca gttggtgtgg taagttattt tatcttgaag aaaaatctaa ggatgtttat
     3301 tgttgtaaag aatgtaggaa gaaggctaag aaggtgaaaa aatgaaagtt tttcttgtaa
     3361 tagatggaga accagttggt aaagaaagac ctagatttaa cttggctact aaaaggacct
     3421 atacaccaca gaaaactaag gactatgaag aattaataaa atggttatat caatctaaag
     3481 ttagacatta ttttactgga tacataaaaa tgactttaag atgttattac tctatagcaa
     3541 aaagtaacag taaaaagatt aaagagcaga aaagaaataa tgtgttaaga cccaataaaa
     3601 aaccagatat tgataatgtg gtcaagatta tagctgattc actcaatgag atagcttata
     3661 aagatgatac gcagattgtt gaggttgtag ctagtaaata ttacagtgat aaaccaagag
     3721 ttgaggttat attagaagat gttatttaac caacggaaaa atccgttcgt tagattaggt
     3781 actcagtttt tcataaaaat gtgaaaaagc tgaatagaga atatatcaaa tggtaaagga
     3841 gagataaatt atgaatgaaa atataaataa agaaataaca gtacttggaa ctttagaaat
     3901 cgagggaatg aaatttcata acattgaggg tggatttgga gaacataaga aagcaatgct
     3961 agtaaaagat atagctgaga tacataatag agaatctaga cagattaatg agcttataaa
     4021 taagaataga aaaagattta aagatggaaa agatatatta gatttgttag gtgtcggttt
     4081 ggacgatacc aaaataaaag aattaggatt tactcaacaa tcaattaatt cttatagagg
     4141 gttaaaaaac aaagggttat tatctgggat ttatatatta tctgaaagag gttatgcaaa
     4201 attattaaaa atattagaag atgatatagc ttgggaatta tatgagaagt tagttgatgg
     4261 atatttctct atgagaaaag aactaaataa tcctctttta agtgcatcaa aggagttaca
     4321 agctatattt atgctagata agaaacaaga agtcttagaa actaaaatag agaatgttaa
     4381 tgagaagtta gagaacttta tggatgatgc accattattc aatatcgagt gtgagtgtat
     4441 tgttaaagag gttaagagag tagcaacaaa atcacttggt ggacatggaa gtaaggctta
     4501 taaaaataaa tctttaagag gtaaagttta tagtgatata taccatcaga ttaaacgaga
     4561 atttggagta gatagttata aggctataaa gcgttgtcaa ttagataaag tattagagat
     4621 tgtaaatagt tataagttac ctatagtgtt tgaagaagaa ataagacttt tgaatagtca
     4681 attatcaatt gtgagttaag acaggaatag atttttctcc tttaaagggg aaaacctgca
     4741 atagttaatt aaaagagaaa aggagtgctt tcacactcca cttgtcaaaa atataaagct
     4801 tttatccaag attattataa cataaacagg agtgtgaaag tatggataat aatattaata
     4861 aaaaagaact atttaaaaaa gtagaaggta gactacatca ttataaattt ttaagtgcag
     4921 aaattaaaaa tcttgaatta gatatagaaa gtagagaaaa tgaaatattt ggttgtaagg
     4981 ctatcgggta tggtgaaaaa gtaagtccaa catatgcttt taattcaact gttgagaatg
     5041 agattataaa aaaagaaaga gatattgcta gattaaaaaa actgaaaaaa gataaagaaa
     5101 tagaaaagaa gaaaatagaa aatgcactta catgcttaga tataagagaa gaacattttt
     5161 ttaaactgtt ttataatagc agaatgaaaa atagtatggt ttatatatcc ttagaaatga
     5221 actcagatag gaaaacatgt agatgtgtaa gggaaagatt agtgtataaa gttatggata
     5281 tgctttatcc aagaattaag gaaaatgaac tcccattatt taaaaattag aaaattcccc
     5341 agtttttccc cagaaattcc cactttattc cctactttct ccccgttttg attaaaaaag
     5401 catgagataa tagtattgtg gaaataaaga tttccctctc aaaacttaat atttgactag
     5461 ggttaaggga ttgccctagt cactatgaac agactaggca gggcatgagg atgctgttag
     5521 ttcaattcta actatgttca atctttagtt tttctatttc aattaatcta cggatacact
     5581 aaaaaatagt atatgaattg agattaaaat ctcatacaat tttgtatctt aattcaaaga
     5641 ctaaaaaccg agtggggctt ggtaacctca ctcaccatgc aagtactggt ttaatctagg
     5701 ttcgattcct ggaacttgct ccctttaata atatgtatcc cccattaaaa aggcttagat
     5761 taacttctag gtctttttta atacaaaaat ttattaaaaa tgcacggcat gcactattca
     5821 gatatgcatg tcatgcatgt ctaaagtcga atatttaata ttttcgatgg ctcaaattga
     5881 ggggtcgaaa ataaaaacag gaggtagtag tatgttgaaa attttacaag agaaaaatgt
     5941 aaaagtaatg tggtccaaaa atggagaaga agtttggttt aatgcaaatg acgtaggaga
     6001 ggaactaggc atagtaaata ttcgtgatac attaagaaat atagatagag aatataaaaa
     6061 gaaatttaat gagtctactg tcggagattc ctacactaga aactttaaag ataaattgcc
     6121 taacttcggt actacttttg ttacagaaga agctgtgtac aatatgtcat ttagaagtaa
     6181 taaaccagaa gcaaagttat ttacaaaatg ggttacaaaa acacttaaac aaattagaat
     6241 acatggttat tatattgcta cagaaaaaga ccaggaatgg ctggatataa ggacagaagg
     6301 caaaaaagta agaaaagatt ttacagatga aatacaagag tttgtatatt atgctactag
     6361 tcaaggtagc aataaacctc agatgtatta taaacatttt actgaacttg taagaaaaaa
     6421 attaggtatt ccaaaaggtg tgaaaagaga tgagttaaat caaagcgaac tatttgatat
     6481 acaagcactt gaaagaatta tatctatgaa attacctaag ttaatagata aagatatgaa
     6541 ttataaagag gtatataaaa agattaagga attaatagaa atgatttaag ggactgtctt
     6601 gatggagggt cttttttaat tcccaaaacg acaaacaaac gaggtggtga tgtgcaagat
     6661 gtcaaagaaa aggtaaaaca agattacata aaaggtatga aacaaaagga aatatcagca
     6721 aagtatgaca ttagtttaaa cactttaaag tcatggataa aaagatacaa ttgggctagt
     6781 gagaaaaaga agggtgcacc taaaaataaa agaggtgcac ccataggtaa taaaaatgcc
     6841 actggtcctc ctggaaataa aaatgctgaa aagtttggtt tcttctcaaa atatctacct
     6901 gaagaaacta gggaattaat acaagaaata tctataaaag ataaatttga tattctttgg
     6961 gaacagataa caattcaata tgcagcaata ataagagcac aaaagataat gtatgttaaa
     7021 gacaaggaag aaatgattaa ggagttaaag aaa
//
LOCUS       DAJMZY010000150         6767 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.154, whole genome shotgun sequence.
ACCESSION   DAJMZY010000150 DAJMZY010000000
VERSION     DAJMZY010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6767)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6767)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6767
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.154"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            <1..853
                     /locus_tag="OE968_003488"
     CDS             <1..853
                     /locus_tag="OE968_003488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220721.1"
                     /translation="KNLKSGVEENFDINLNKSDFKENSWKTLFNKIYKGNLYMVISET
                     NISGSKVNNICILKIDIKNKSYKLLNRFNLGLQNGEQQNINEIKFSIGSKLYLEIVNN
                     KSKNGYIEGHDSYSNFIIYDIEDNTFNISNKFMDNLNKEKNANPKEIGLLSKTKLDYM
                     VKNNKLNLIVTDMSNSITNLVYDINSNEIKLEDYEILDLKVDYNEASSGVRKVKLLDD
                     KIYSISGIKNSISGELKGFKGIVDVVGTKPVKFQVFDMKLKKNIYEAELINGDISLQE
                     KLFFVAN"
     gene            1219..2400
                     /locus_tag="OE968_003489"
     CDS             1219..2400
                     /locus_tag="OE968_003489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HCP7220722.1"
                     /translation="MNKKYIKAGNLIDGTGNSIMQNKGIIIDGDTIVEIEDIRDDLNG
                     YDVYDYLDKTVMPGIMNCHVHLTMEPVGNPKIYYDNVSDVELVVNTIKQLDAYLDSGV
                     TYIRSLGCPKYVDVQLKNLIDKGSIDGPGIVTSGPVICMTGGHGYYFGIESDGVDECR
                     KSARTVLKNGVDCVKIMATGGVTTDGVEPGSPQLTLEEMKAAVDEAIKAGKITATHAQ
                     GRTGIKNAVLAGITSIEHGVYLDDEIIDLMLERGTYLVPTVAAPYFILNAGKESGITE
                     ATLRKCEIVAIPHKESFLKAYKKGIKIAVGSDAGTSYNEHGKTYYEMKLMSDYGMDNM
                     DIIVAATKTASELLRIDKNYGTLEKGKKADVIVVNGNPVENIDVLADVLAVFKLGKKV
                     R"
     gene            complement(2542..3459)
                     /locus_tag="OE968_003490"
     CDS             complement(2542..3459)
                     /locus_tag="OE968_003490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220723.1"
                     /translation="MENNKCREDFRFTQEYEEDYPNTNERYYENYQVADRYYNYPNKY
                     KEPKIKQCCCKKSMREALELLRYDALRPFVNFNQFAFISDFFIVGANLVGIDLSAPPK
                     DNLSGLDGTFERFSACNCDLIDIAGRVSYPIPVPLTLEGLINTIGTIPGVAELIALID
                     AVIPPTIDLGAILDAILAAIIDFILAASTPLANVDLASLCNLKAVAFDITPADYEDFI
                     ASLGYYLDKKHYKECNCNCDCDDCCCNKGILDNLYMSNINNQVTVVAGSLVLTGVEVL
                     GKKNDVIVLGNSNDSRIYFVCVDSIDYIA"
     gene            3712..4506
                     /locus_tag="OE968_003491"
     CDS             3712..4506
                     /locus_tag="OE968_003491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCP7220724.1"
                     /translation="MIEVDKLCKSFTRVVKDDKNKSSIRKLKKVKTKKEEFFAVNNVS
                     FKVMEGEIVGILGPNGAGKTTLLRMLGGILTPTSGSINISGYDYSIDRNSAKKEIGYL
                     SGNTKLYGRLSPRELLTTFASLYEMSKEDIEESIENIVKIMDMSEFIDNRIENLSTGQ
                     TQRTSIARCLIHSPKVYIFDEPTLGLDVLSSASIIDFMKNEKLRGKTVLYSTHYMEEA
                     ETLCDKIFMIHNGKIIASGTPQSLKEESGVNNLRDVFIKLARKEDI"
     gene            4507..6567
                     /locus_tag="OE968_003492"
     CDS             4507..6567
                     /locus_tag="OE968_003492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HCP7220725.1"
                     /translation="MRSKIVKYIFKKEMLDILRDKKTLFMMIVVPLLLYPLLMLLMIQ
                     VMNMSASSMNSKDINIAFNNKPNKVLVSMIEDDNLEKDTKNTSNDKGKIRVLDVDNYK
                     KSLEENKIDAYIKMEEKKSSINYQIYINSSQENSSNALKRIETVLDKYKRFTIEKTLS
                     EKGLDVQATLEPITYSTVDVAKTEEVAGYFLGQILPFILIIGVLLGSIYPAIDVMAGE
                     KERGTLETLFTLPISNLELVMGKYMAVSLSAIVTAILNILSMGLTMAFILVSGGISSQ
                     FGFGNFNYGDLVLPIITTLICICLFSMVVSAISMCVCSLAKSFKDAQNYITPLMLIIM
                     IPSYVSMIPNIVLDRVTAVIPVVNISLLIKSVLSFKSDLNLIALVLASNVAFVILAII
                     LLSKMFNSEEILFGNSKSFSFLEKRSNIKKGSIPTVSDGVILYAVGLVLLIYVGSLVQ
                     IKFGMAGIIMTQFMIISLPLLFAYYIKADFKEVFSLKVPKLKHVFGSIVLWIGGYILI
                     MIITQLILFLFPQNMEVAESLNKALFIKDSVLLNLLAIALLPALCEEMFFRGFIFSSF
                     SKSKDKNKSIKLAIICSGVLFGIMHMDFIRIIPTSILGIIFAYSVYKSGSIFVSMLLH
                     FLNNSVAVVLNHYTTGNITNLYKFVEVDFSNLNVLKFALILLISLILIMLGLRVLDRK
                     SLRN"
BASE COUNT         2644 a          708 c         1085 g         2330 t
ORIGIN      
        1 taaaaattta aaaagtgggg tagaagaaaa ttttgatatt aatttaaata agtctgattt
       61 taaagaaaat agttggaaaa ccttatttaa caaaatatat aaaggtaatt tatatatggt
      121 aattagtgaa actaatattt caggttctaa agtcaataat atttgtatat taaagataga
      181 tataaaaaat aagtcttata aattattaaa tagatttaat ttaggattac agaatggaga
      241 acaacaaaat atcaatgaaa ttaaattttc tattggaagt aaattatact tagaaatagt
      301 aaataataaa agtaaaaatg gatatattga aggacatgat agttactcta actttattat
      361 atatgatata gaagataaca cttttaatat aagtaataaa tttatggata atctaaacaa
      421 agaaaagaat gcaaatccaa aggagattgg cttattaagt aaaactaagc tagattatat
      481 ggtaaaaaac aataaattga atcttatagt tacggatatg agtaattcca taactaatct
      541 tgtttatgat attaattcta atgagattaa attagaagat tatgagatac ttgatttaaa
      601 agtagattat aatgaagcat catctggagt taggaaagtt aagctactgg atgataagat
      661 atattctatt tcaggtatta agaacagtat atcaggagaa ttaaaaggat ttaaagggat
      721 tgttgatgta gtcggaacta agccagtaaa atttcaagta tttgatatga aacttaaaaa
      781 gaatatttat gaagctgagc taataaatgg agatataagt ttacaagaaa agttattttt
      841 tgttgcaaat taagtgttag aattaatttt agaactttaa acttttatat gtatcacaga
      901 taagtataag taagggagtg tctcaaaata aactttttag ctcatgagac acttttttta
      961 tatgaaatca aatatatttt cattgtttag atttattttg ataatgaaaa aaagattatc
     1021 tttattttaa gaaagacatt tatttataat tatatacaaa aatatttttt aatgtttttg
     1081 tgtataatta taacaattta atttatatta atgcacttaa atttgaaata gaatgcttat
     1141 agtggtaaaa ttaattatta gaatattaga aataataaat aaataataca ttgtacttaa
     1201 aagggggaga aatttaagat gaacaaaaaa tatattaaag cagggaattt aattgatgga
     1261 accggaaata gtattatgca aaataagggt ataattattg atggagatac tatagttgaa
     1321 attgaagata taagagatga tttaaatgga tatgatgtgt acgattactt agataaaact
     1381 gttatgccag gcattatgaa ttgtcatgtt cacttgacaa tggagccagt tggaaatcca
     1441 aagatatatt atgataatgt atcagatgta gagcttgtag taaatacgat aaaacaactt
     1501 gatgcttatt tggattcagg agtaacatat attagaagct taggttgtcc caaatatgtg
     1561 gatgtacaac ttaaaaatct tatagacaaa gggtctatag atggtcctgg tatagttact
     1621 tcaggtccag ttatatgtat gacaggaggg catggatatt attttggtat tgaaagtgat
     1681 ggagtggatg aatgtagaaa atcagccaga acagttttaa aaaatggagt agattgtgta
     1741 aagataatgg caactggagg tgtaacaact gatggagttg agccagggtc accacaatta
     1801 actttggagg aaatgaaggc tgctgtagat gaagctataa aagcaggtaa aataactgcc
     1861 acacatgcac aaggaagaac tggtataaaa aatgcagtgc ttgcaggaat tacttctata
     1921 gaacatggtg tttatttaga tgatgaaata attgatttga tgcttgaaag aggaacttac
     1981 ttagttccaa ctgtggctgc accatatttt attctaaatg caggaaaaga aagtggaata
     2041 actgaagcta ctcttagaaa gtgtgagatt gttgccattc cacataaaga gtcattccta
     2101 aaagcatata aaaaaggaat taaaattgca gttggttctg atgcaggaac ttcttataat
     2161 gaacatggaa aaacatatta tgaaatgaaa ctaatgtcag attatggtat ggataatatg
     2221 gatataatag ttgctgctac aaaaacagca tctgaacttt taagaattga taaaaattat
     2281 ggaactctag aaaaaggaaa gaaagcagat gttatagttg taaatggaaa tccagtagag
     2341 aatatagacg tacttgcaga tgtgttagca gtatttaaac ttggtaaaaa agttagataa
     2401 atagtataaa aataaaaaag agtgtctaaa gaaattttta aataattata gacactcttt
     2461 tttattagta ataattaaat cttttatact ttagaaaata gattctattt tatatttaga
     2521 tataactctt taaaatcatt cttatgcaat ataatctata gaatctacac atacaaagta
     2581 tattcttgaa tcattagaat ttccaagtac tataacatca tttttcttac ctagaacttc
     2641 aacaccagtt agaaccaaac taccagctac tacagtaact tgattattta tatttgacat
     2701 ataaagatta tctaggatac ctttattaca acagcaatca tcacaatcgc agttgcaatt
     2761 acattctttg taatgttttt tatcaagata gtaacctaaa gatgctatga aatcttcata
     2821 atctgcaggt gtaatatcaa atgcaacagc tttaagatta cacaatgatg ctaaatctac
     2881 gtttgctaat ggagtagatg cagcaagtat aaaatcaatt atagcagcaa gtattgcatc
     2941 taatatagcc ccaaggtcta tcgtaggagg aataactgca tcaataagtg caattaattc
     3001 agctactcct ggtatagttc ctatagtatt aattaatccc tcaagagtta aagggactgg
     3061 aataggataa gatactctac cagctatatc tattaaatca cagttacaag cagaaaatct
     3121 ttcaaaagta ccatcaagtc cagataaatt atcttttgga ggagctgaaa gatctatacc
     3181 taccaaatta gcacctacta taaagaaatc tgagataaaa gcaaattgat taaagtttac
     3241 aaaaggtctt agagcatcat atcttagaag ttctaatgct tctctcatac tttttttaca
     3301 acaacattgt tttattttag gttctttata tttatttgga taattatagt atctatcagc
     3361 tacttgataa ttttcatagt atctttcatt tgtatttgga taatcttcct catattcttg
     3421 tgtaaatcta aagtcctctc tacatttatt attttccact aaatacactc cttttatatt
     3481 ttaatttaaa tgtatagata attaagctta tctatatagt aatattatat ttataatgta
     3541 aaaaaatgtt acaaaagata ttataaacga ataaaaaata ataatttgcc agataaactt
     3601 gtaaattttt atgaataatc cattctaaaa caaaaaactg tgtataaaaa aggtttatat
     3661 gttatattta tataaatata acatatgaac gagaaaggag tggtttgata aatgattgag
     3721 gtagataaat tgtgtaagtc ttttacaagg gttgtaaaag atgataagaa taaaagttca
     3781 ataagaaagc taaagaaagt aaaaactaaa aaagaagaat tttttgctgt aaataatgtt
     3841 tcatttaaag ttatggaagg tgaaattgtt ggaatattag gtccaaatgg tgcaggaaag
     3901 actacattac ttagaatgtt aggtggcata ttaacaccaa catcaggaag tataaatatt
     3961 tctggatatg attattcaat agatagaaat tcagcaaaaa aagaaatagg ttatctctct
     4021 ggaaatacaa aactatatgg aaggctttct ccgagagaac ttctaacaac ttttgcaagt
     4081 ctatatgaga tgtcaaaaga agatatagaa gaatcaattg aaaatattgt aaaaataatg
     4141 gatatgagtg aatttataga taatagaatt gaaaatctat caactggtca gactcaaaga
     4201 acatctatag ctcgttgttt aatacattct ccaaaagtat atatttttga tgagccaaca
     4261 ctaggtctgg atgttttaag tagtgcatct attatagatt ttatgaagaa tgaaaaacta
     4321 aggggaaaaa ctgttcttta ctcaactcat tatatggaag aagcagaaac tttatgtgac
     4381 aagattttta tgattcacaa tgggaaaata attgcatcag gaacaccaca gagtttaaaa
     4441 gaggaatctg gagtaaataa tttgagagat gtattcataa aacttgccag aaaggaggac
     4501 atttaaatga gaagtaagat tgtaaaatac atatttaaaa aagaaatgtt agacatattg
     4561 agagataaaa agactttatt tatgatgatt gttgtgccac ttcttttata tcctttactt
     4621 atgttattaa tgattcaagt aatgaatatg tctgcaagta gtatgaatag taaggacatt
     4681 aatatagctt ttaataataa acctaataag gttttagtat ccatgattga agatgataat
     4741 ttagaaaaag atactaaaaa tacttcaaat gataaaggca aaataagagt gttagatgta
     4801 gataactata aaaagtcatt agaagaaaat aaaattgatg cttatataaa gatggaagaa
     4861 aaaaaatcat ctataaatta tcaaatatat ataaattctt ctcaagaaaa ttcttctaat
     4921 gcactaaaaa gaattgaaac tgttttggat aaatataaaa gatttaccat agaaaaaact
     4981 ttatctgaaa aaggattaga tgtacaagct actttagaac caataacata tagcactgta
     5041 gatgttgcaa agacggaaga agtggcagga tactttttag gtcagatact tccatttata
     5101 ttaataatag gagttttact aggttcaata tatccagcaa tagatgttat ggctggagaa
     5161 aaggaaagag gtacattaga aacattattt acactgccaa tatcaaactt agaactggtt
     5221 atgggaaaat atatggcagt ttctcttagt gcaatagtaa cagcaatttt aaacatttta
     5281 tctatgggac tgactatggc atttatttta gttagtggag gtattagtag ccaatttggc
     5341 tttggaaact ttaattatgg agacttagtc ttaccaatta taactacttt aatttgcata
     5401 tgtctttttt caatggtagt ttcagcaata agtatgtgtg tatgttcatt agcaaaaagt
     5461 tttaaagatg ctcaaaacta cataacacct cttatgttaa ttattatgat accatcatat
     5521 gtttctatga taccaaatat agtattagat agagtgacag ctgtaatacc tgtagtaaat
     5581 atatctttac ttataaaaag tgtattatct tttaaaagcg atttaaattt aatagcctta
     5641 gttttagcat caaatgtagc ctttgttata ttggcaatca tactactgtc taagatgttc
     5701 aattctgagg aaatactttt tggtaatagt aagagtttct ctttcttaga gaaaagaagt
     5761 aatataaaaa aagggtctat accaactgta agtgatggtg ttattttata tgcagtagga
     5821 ttagttctat tgatttatgt tggttcttta gttcaaatta aatttggtat ggcaggtatt
     5881 ataatgacac aattcatgat aatttcttta ccgttattat ttgcatacta tattaaagct
     5941 gattttaaag aggtatttag cttgaaagtt cccaaattaa agcatgtgtt tgggagcatt
     6001 gttctttgga ttggtggata catacttatt atgattataa cacagctaat tttattctta
     6061 tttcctcaaa atatggaagt tgctgaaagt ttaaataagg ctctttttat caaagatagt
     6121 gttttactga atttactagc aatagcttta ttaccagctt tatgtgaaga aatgtttttt
     6181 aggggattta tattttcttc atttagtaaa tcaaaagata aaaataagtc tatcaagcta
     6241 gctataatat gcagtggggt actatttggt attatgcata tggattttat tagaataatt
     6301 ccaacatcaa tattaggtat tatatttgca tatagtgtgt ataaatctgg ttcaatattt
     6361 gtatcaatgt tattgcattt tttaaataat agtgtagcag ttgtgttaaa tcattataca
     6421 actggaaata taaccaactt atataaattt gttgaagttg atttttcgaa cttaaatgta
     6481 cttaaatttg ccttaattct tctaataagt cttatattaa ttatgttagg attaagagtt
     6541 ttagatagaa agtctttaag aaattaagta taaagttatt atatagatta aaatattaat
     6601 aagcactaaa gtatatggat atatcttgta tataaaaata ctttagtgct attttatata
     6661 ttttaattat atgaattatt tatcgtttca tttatgtaat gaaaatgtta tataaatgaa
     6721 acaataaata atttttattt tagaaattta tatttaaata atcaagt
//
LOCUS       DAJMZY010000151         6755 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.155, whole genome shotgun sequence.
ACCESSION   DAJMZY010000151 DAJMZY010000000
VERSION     DAJMZY010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6755)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6755)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6755
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.155"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            complement(<1..515)
                     /locus_tag="OE968_003493"
     CDS             complement(<1..515)
                     /locus_tag="OE968_003493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2140 domain-containing protein"
                     /protein_id="HCP7220726.1"
                     /translation="MGKVAKILLSLIVIVLVLVGIVVYILTPKERYDVSSQNNKIIDE
                     EYLSKGSYINSMEVVKNPLRMVGKISVSEEEFKNLIYTLMQKHGINELENNFVEMKNG
                     KIKVAGPYKVFGLVNSQYELELRPTLKDGNLVVSLENVKIGKFKLSDKMLEKILSNYN
                     KKVPFEVNGNK"
     gene            807..2471
                     /locus_tag="OE968_003494"
     CDS             807..2471
                     /locus_tag="OE968_003494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--tRNA ligase/YqeY domain fusion
                     protein"
                     /protein_id="HCP7220727.1"
                     /translation="MSNETNSSNFIKNIIINDLETGKHDSIITRFPPEPNGYLHIGHA
                     KSICLNFGLAKEFNGKANLRFDDTNPLKEDVEYVESIKEDVKWLGFDWNELNFASNYF
                     DEMYKRALILIKKGKAYVCDLTQEEMREYRGTLTEPGKESPHRNRTIEENLDLFERMK
                     NGEFKDGEKTLRAKIDMSSPNINLRDPIIYRISHSTHHNTGDKWCIYPMYAFAHPIED
                     AIEGITHSICTLEFEDQRPLYDWFVKECEMENIPRQIEFARLNINNTVMSKRKLKQLV
                     DEGIVDGWDDPRVPTISGIRRKGYTAEALRNFCSEIGVSKVNSTVDSQMLDYFLRENL
                     QPKAPLTMGVLRPLKLIITNYPEDKIEMLEIENNAKDESQGKRLVPFSRELYIEQDDF
                     MEEPVKKYFRFFPGNEVRLKGAYFVKCTDVIKDENGNVVEIHGTYDPETKSGSGFTGR
                     KVKSTIHWVDAKSAIPCEFRLFEPLILDDIPENEGKHFLEQINPNSLEILQGFVEPTQ
                     IKDAKPFDKFQFVRNGFFSIDNKYTTDEKFVFNRIVPLKSSFKPGK"
     gene            complement(2578..3477)
                     /locus_tag="OE968_003495"
     CDS             complement(2578..3477)
                     /locus_tag="OE968_003495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegS/Rv2252/BmrU family lipid kinase"
                     /protein_id="HCP7220728.1"
                     /translation="MKKVKLIYNPNSGEKKILSNLDTIIELYQEKNYLLIPYRLTIKE
                     PVKNAFKEVDSSYEHILIAGGDGTVDLVVNAMKELDIKIPIGILPTGTANDFSNALQI
                     SFDIKEAINEIINSKPKKIDIGKVNNKYFINVASAGMFTDVSQRINTDLKNSFGRISY
                     YIKGIEEALYMRKFKIKVSSEEMYYDGDMYLMLIFNGKTAGNINLAYKAEIDDGYLDV
                     IIFKGMPIPKSIPVLISVLRGDYLDQYNGNEILYFKTKKVHIECEDSLITDIDGEKGP
                     DFPLNIECIKDGIEVMGICSEKS"
     gene            complement(3504..4142)
                     /locus_tag="OE968_003496"
     CDS             complement(3504..4142)
                     /locus_tag="OE968_003496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003356606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate utilization protein"
                     /protein_id="HCP7220729.1"
                     /translation="MDQNLNWLNEKRIEKTIKSLENNNMKGYLVSNKEELLKKIEEIV
                     KAGSLVGCGGSMTLFETGVIDFIREKYNFLDRYAKDIKPEEMKEIYRKSFSADAYFTS
                     TNAITEDGELYNLDGNGNRVAAMIYGPDKVIVIAGVNKIVKDVDEAIKRTKTIAAPAN
                     CKRLSTNTGCKTTGICIDCSSPGRICCSYTLIKRQLTPERIHVIFLNEDFGY"
     gene            complement(4479..5477)
                     /locus_tag="OE968_003497"
     CDS             complement(4479..5477)
                     /locus_tag="OE968_003497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4003 domain-containing protein"
                     /protein_id="HCP7220730.1"
                     /translation="MEQSFINGKVNLLIENYKALNEVKGSWQMGLIQHSCALAFTLKN
                     KKISPRLVEERIELIKKNTGLFSNFRGYNMFYMATLLSFESNPESSFKMILDIYKELK
                     SEKFWGDTYLPLTASIVYENREKMDYLTCISKMKIIYDYMRKKHPFLTSSDDYCNIAL
                     IAIHSKNLDEDLEYIEKCYEFLNENGFYKGNDLQALSQILLFSDDRTMLKCKKTIELK
                     KAFKENDCKMNYYGYPIIGAISLLDYREDEIIEEIKNVSNKLKEEKGFGNWSLGKSNR
                     VMISSAIVASIYADLIRNENNIGSITNNIFLNIVVAIQIACVMAATSAAIASSSSN"
     gene            complement(5575..6150)
                     /locus_tag="OE968_003498"
     CDS             complement(5575..6150)
                     /locus_tag="OE968_003498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220731.1"
                     /translation="MKLKEALITCVVCSVCLTPLLVNGETKIDADHCKESIVNIDTIV
                     KSGKSFNSKYNQGMEDYKNSDEYKLKVQKEKLQNQLGIKIKKLVPITFEVSYYTSLNQ
                     ENGYGAITATGDDLEDGFVANNHLSFGTKIIVDGKLKTVMDRGSSKYFSNSNAIDVFV
                     PKWSNESESEYYDRVNNMGRHYKKGYIIVEE"
     gene            6466..6729
                     /locus_tag="OE968_003499"
     CDS             6466..6729
                     /locus_tag="OE968_003499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220732.1"
                     /translation="MIKNTKQITVEVNEILLQEMSKITNYENNILTDLINESIVNYIL
                     ENKKHNIENKDLEEVIKFYKKENTEKPKSAARAIAEAKTHTLY"
BASE COUNT         2350 a         1043 c          750 g         2612 t
ORIGIN      
        1 atcttatttc cattaacctc aaatggaact tttttattgt agttacttaa tattttttct
       61 agcattttat cacttagttt aaattttcca attttcacat tctcaagact tacaactaag
      121 tttccatcct ttaaagtagg tctcaattca agttcatatt gactatttac caaaccaaat
      181 accttatatg gtcctgctac ctttatttta ccatttttca tttcaacaaa attattttca
      241 agttcattaa ttccatgctt ctgcatcaat gtatatatta aatttttaaa ctcttcctct
      301 gaaacagata tttttccaac cattctaagt ggatttttta ctacctccat agaatttata
      361 tatgagcctt ttgataaata ttcttcatct atgattttat tattttgtga actaacatca
      421 tatctttctt ttggtgtcaa gatatataca acaattccta caagtactaa aacaataaca
      481 attaaactta acaaaatctt tgcaaccttt cccataatcg tctcctttac aaatctgtca
      541 tcagatttaa aataaattta gataactaac ttcacataat attcttaaca atatacatac
      601 tataatacag tcttttaaaa attaattcaa ccaatctaat gttttgtaaa taaactgtaa
      661 aaacatgttt ttagtataaa agttaatatt ttgcataata ctcttaatta cacctttatt
      721 tttttctaat cttggattaa aattaatatt atgcaataca gtgtagtgtt ctgtattata
      781 atcaaattaa ataggaggta tagaatatgt caaatgaaac gaactcatct aactttataa
      841 agaatattat tataaacgac ttagaaacag gaaaacatga cagtatcata actcgttttc
      901 cacctgagcc aaacggatat ttacatattg gtcatgcaaa aagtatatgt cttaattttg
      961 gattagctaa ggagtttaat ggaaaagcta atttaagatt tgatgataca aacccattaa
     1021 aagaggatgt tgaatatgta gagtccataa aagaagatgt aaagtggtta ggatttgatt
     1081 ggaacgagtt aaattttgca tctaactact ttgatgaaat gtataagaga gctttaatac
     1141 taataaaaaa gggtaaagct tatgtatgtg atttgacaca agaggaaatg agagaatatc
     1201 gtggtactct aactgaacca ggaaaagaaa gtcctcatag aaacagaact attgaagaaa
     1261 accttgattt atttgaaaga atgaaaaatg gtgaatttaa agatggtgaa aaaacattaa
     1321 gagccaaaat agatatgtct tctccaaata taaaccttag agacccaatt atatatagaa
     1381 tatctcattc aacacaccat aatacaggag ataaatggtg catatatcct atgtatgctt
     1441 ttgctcatcc aattgaagat gcaattgaag gaataactca ctctatatgt actttagagt
     1501 ttgaagacca aagacctctt tatgattggt ttgttaaaga atgtgagatg gaaaatatac
     1561 ctagacaaat agaatttgct agacttaata taaataatac tgtcatgagt aaaaggaaat
     1621 taaaacaact tgtagatgag ggtattgttg atggttggga tgaccctcgt gttcctacaa
     1681 tatccggaat cagacgtaag ggatatactg cagaagcatt gcgcaatttc tgtagtgaaa
     1741 taggggtatc aaaagttaac tctacggtag atagtcaaat gcttgattat ttcctaagag
     1801 aaaacttaca accaaaggct cctcttacta tgggagtttt aagaccttta aaacttatta
     1861 taactaatta cccagaagat aagattgaga tgcttgaaat agagaataat gctaaagatg
     1921 aatctcaagg aaagagatta gttcctttct ctagagaatt gtatatagaa caagatgatt
     1981 ttatggaaga acctgttaag aaatatttta gatttttccc aggaaatgaa gtccgtttaa
     2041 aaggtgctta ttttgtaaaa tgtactgatg taattaagga tgaaaatgga aatgtagttg
     2101 aaatacatgg tacttatgac cctgaaacta agagtggctc tggctttaca ggacgtaagg
     2161 taaaatctac aatacattgg gttgatgcta aatcagctat cccatgtgaa tttagattat
     2221 ttgaaccatt aattcttgat gatatacctg aaaatgaagg taaacatttc ttagaacaaa
     2281 taaatcctaa ttcattggaa atattacaag gttttgttga acctacacag ataaaagatg
     2341 ctaaaccttt tgataaattc caatttgtta gaaatggatt ctttagtata gataataaat
     2401 atacaactga tgaaaaattt gtatttaata gaatagttcc tctaaaaagt tcttttaaac
     2461 caggtaaata atcttacaat caaaaaatga agacttaaaa tataaattac ttctactata
     2521 aataaactta gttagaagta attttttatt tgagtcttca tcatttactt taaatgatta
     2581 acttttttca ctacagattc ccatgacttc tattccatct tttatgcatt ctatgttaag
     2641 aggaaaatct ggtccttttt ctccgtcaat atctgttata agtgaatctt cacattctat
     2701 atgcaccttt ttagttttaa agtatagtat ttcatttcca ttatattgat ctaaataatc
     2761 acctctaagc acacttatca aaactggtat tgattttggt attggcattc ctttaaaaat
     2821 aattacatcc aaatatccat catctatttc agccttatat gctagattta tatttcctgc
     2881 tgttttgcca ttaaaaatca acataagata catatctcca tcataataca tttcctcaga
     2941 agatactttt atcttaaatt tcctcatata caatgcttct tctattccct ttatataata
     3001 agaaattctt ccaaatgaat tttttaagtc tgtgtttatc ctttgtgata catccgtaaa
     3061 cataccagca cttgcaacat ttataaagta cttattattg actttcccta tgtctatttt
     3121 ctttggtttt gaatttatga tttcatttat agcttctttt atatcaaatg aaatttgaag
     3181 agcatttgaa aaatcatttg cagttcctgt aggcaaaatt ccaattggaa tttttatgtc
     3241 taattctttc attgcattta ctactaaatc tacagtacca tcaccaccag ctatcaatat
     3301 gtgttcataa gaactatcaa cttccttaaa tgcattcttt acaggttctt taatagttaa
     3361 tctatagggt atcaataaat aatttttttc ttgatataat tctatgatag tgtctaaatt
     3421 tgataatatc tttttttcac ctgaattagg attgtatata agttttactt ttttcattat
     3481 ttctccttac tcattttatt cttttagtat ccaaaatctt catttaaaaa aatcacatgt
     3541 attctttctg gtgttaattg tctttttata agtgtataac tacagcatat tcttcctgga
     3601 cttgaacagt ctatacatat accagtagtc ttacatccag tatttgtact taatctttta
     3661 caattggctg gagcagctat tgtttttgtt ctttttatag cttcatctac atctttaact
     3721 attttattta ctcctgctat aactattact ttatcaggtc catatatcat agcagcaact
     3781 ctattcccat tcccatctaa attgtaaagt tctccatcct ctgttatcgc attagtactt
     3841 gtaaaataag catctgcaga aaatgacttt ctatatattt ctttcatttc ttctggtttg
     3901 atatcttttg catatctatc aagaaaatta tatttttctc ttataaaatc aatcactcct
     3961 gtttcaaata aggtcataga acctccacat cctactagag aacctgcttt aactatttct
     4021 tcaatttttt taagaagctc ttctttgtta cttactaaat accctttcat attattgttt
     4081 tccaaagatt ttattgtttt ttctattctt ttttcattaa gccaatttaa attttgatcc
     4141 attttaactt cccccttatt tttaatatgt acttaattat ttataaactt tattttcttt
     4201 ataagtttat tttagtacat ctaaaaaaaa atacaatata aaacttaaat agttttacat
     4261 aattttttcc aaaataactt actcaatcaa aaaaggaaag tagatgtact attctacttt
     4321 ccctatattg tatgtagtat ttattgccta aaatctatat attaattata tgtttcatat
     4381 tatataatat cacagttaat taaaatgtaa tactatcttc tttttaaaca tataaattgt
     4441 attattaaat ttaatatatc caacttcaat aaatcttatt aatttgatga agaagatgct
     4501 atagctgcac ttgttgctgc cattacacat gcaatttgaa tagcaacaac aatatttaaa
     4561 aatatattat tagttataga gcctatatta ttctcatttc gtatcaaatc tgcataaatt
     4621 gaagctacaa tagcagaact aatcattact ctattacttt ttcctaaaga ccaatttcca
     4681 aagccttttt cttctttaag tttatttgaa acatttttta tctcttctat tatttcatct
     4741 tctctataat ctaataatga aattgctcct attattggat atccataata attcatttta
     4801 caatcatttt ctttaaatgc ttttttaagt tcaatagtct ttttacattt aagcatagtt
     4861 ctatcatcac taaataaaag aatttgggat aatgcttgta aatcatttcc tttataaaaa
     4921 ccattttcat ttagaaattc ataacatttt tctatgtatt ctaaatcttc atctaaattt
     4981 tttgaatgaa ttgcaataag tgctatatta caatagtcat cactagaagt tagaaatgga
     5041 tgttttttcc tcatgtaatc atatattatt ttcatttttg atatacatgt aagataatcc
     5101 attttctctc tattttcata aactattgat gctgtaagtg gtaaatatgt atcgccccaa
     5161 aacttttcac ttttaagttc tttgtatata tctaaaatca tcttaaaact actttctgga
     5221 tttgattcaa acgaaagtag tgttgccata taaaacatat tatatcctct aaaattagag
     5281 aataatccag tatttttttt aataagctct attcgttctt ccactaatct aggacttatt
     5341 ttcttgttct taagggtaaa tgcaagtgca caactatgtt gtatcaatcc catttgccaa
     5401 gaacctttaa cttcatttaa tgctttgtaa ttttctatta ataagtttac ttttccattt
     5461 ataaacgatt gttccatatt gccctcctag taatatatct cattgtacta atagttttat
     5521 atttattata tatatattaa atactacaat caatacatat tacttcaaag aacatcattc
     5581 ttcaacaata atgtagcctt ttttgtaatg tcttcccata ttattgactc tatcatagta
     5641 ctctgattca ctttcattac tccatttggg cacaaataca tctattgcat tagaattact
     5701 aaaatactta ctagaccccc tatccataac agtttttaat tttccatcta caataatctt
     5761 agttccaaaa cttaagtgat tgtttgctac aaaaccatct tctaaatcat ctcctgtagc
     5821 agttatcgct ccatatccat tttcttgatt aagacttgtg taataactaa cttcaaaagt
     5881 tataggtact aacttcttta ttttaatacc taactgattt tgtagtttct ccttttgtac
     5941 tttcaactta tactcatcac tatttttata atcttccata ccttgattat acttggaatt
     6001 aaagctttta cctgacttta ctatagtatc tatatttact atagattctt tacaatgatc
     6061 tgcatctatt tttgtttctc catttaccaa taatggagtt aaacatacac tacatacaac
     6121 acatgtaatc aatgcttctt taagcttcat aaattccccc cttattattt tgatatatta
     6181 gcatatttaa tattatatgt ctacatttag atttaaatac cacacccatt tgctttaaga
     6241 agttgtctta tatttaattc accttaaaca cttataaatc ctctatctta gaatcatata
     6301 gaataaagct tttatcatta aatatttttt attaatcttt taaaatctaa aactacttta
     6361 tctaattttc tcttttttag aatttaagaa ttaaaattct ataattttaa aacatattga
     6421 atttattttt ttgagatgat ataattttct taagaggtgg ttgatatgat aaaaaataca
     6481 aaacaaatta cagtagaagt taatgaaatt ttattacaag aaatgtctaa gataactaat
     6541 tacgaaaata atattttgac agatttgata aatgaatcaa ttgtaaatta tattcttgaa
     6601 aacaaaaaac ataatattga aaataaagat ttagaagaag tgattaaatt ttataaaaaa
     6661 gaaaatactg aaaaacctaa aagtgcagca agagctatag ctgaagcaaa aactcatact
     6721 ctgtattaat caaataaaaa agttcctaaa aacta
//
LOCUS       DAJMZY010000152         6701 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.156, whole genome shotgun sequence.
ACCESSION   DAJMZY010000152 DAJMZY010000000
VERSION     DAJMZY010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6701)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6701)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6701
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.156"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            401..1675
                     /locus_tag="OE968_003500"
     CDS             401..1675
                     /locus_tag="OE968_003500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HCP7220733.1"
                     /translation="MQFMDVSKYIEGANLKVKTKNGETVKRIYFNNSATPLVLKNVVD
                     NLNCEIPWLTYINAPGIISEKNTLKYENVRSTILKLIDGDEEKDSVIYVKNATEGINF
                     LAKFFKDENPDKFVITTAMEHMANYLPFKVNFPTKVVGITEKGELDLCQLENILKNYA
                     GNVSLVTVTGASNVTGITTPIYEIARIAHKYGAKILVDIVQVIQHKPFSMMPHECDEH
                     IDFVVFSAHKCYSPLNGGALVGPKKFFEKFNPVLYGSGSTKFVNDNKILYANVPQRFE
                     AGYPEYFGTLAMGKALNTLNKIGLNRISKYERELFLYAKEEMSKIPNIIIYGDKSNNV
                     IIPNISFNISNMYYKDVAKYLVDNFGIETGAGVVGADIYVQKLLGINPKEAYVRFMRE
                     NPVGLVRISLGMYNTFDEVDSFIHAIKTLAFK"
     gene            complement(1882..2199)
                     /gene="trxA"
                     /locus_tag="OE968_003501"
     CDS             complement(1882..2199)
                     /gene="trxA"
                     /locus_tag="OE968_003501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HCP7220734.1"
                     /translation="MVKIINNNEFINEVENKDGLVVVDFFATWCGPCKMLSPIYEALG
                     NEMVEKANFLKVDIDQSIELAQKFEVSTVPTMLIFKDGKPVDRLIGFMPKENLKNKIE
                     SYM"
     gene            2466..3218
                     /locus_tag="OE968_003502"
     CDS             2466..3218
                     /locus_tag="OE968_003502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrmB family transcriptional regulator"
                     /protein_id="HCP7220735.1"
                     /translation="MDNIINELQNIGFTKYESQIYISLLKESPLTGYEISKLSGVPQS
                     KVYENITKLLNNNIIINVGTDPIKYIPINPNELLKNKKKEFDNSMDNLKNSLQILNKS
                     KSVEYVLNIKGDKNILKKAIEMIKNAKQEIIISCPYEEILELKKELLIAYKKNINIEI
                     LLLENKSLKGLDNIHIHGGNKTTLENKMLYKGIILIVDNDEILTGNLSEGSEAISIWT
                     KNSNILYIGVQYIKHEIYISEQIKGGYKNEQN"
     gene            3205..4086
                     /locus_tag="OE968_003503"
     CDS             3205..4086
                     /locus_tag="OE968_003503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HCP7220736.1"
                     /translation="MNKIKIKQVDAFTTIPFGGNPAGVVTDASNISDEIKQNVAKEMN
                     LSETAFVSESNIADFKVQFFTPGLEVDLCGHATIGTFHALLEEGKLNTNKSIFYQETK
                     AGVLSVELKKINNENIFMMEQNTPEFENLDNCRKELAQMIGVHEDRLLEYPIIKVNTG
                     LWWLVFGLKSLDDLKNISPDLNKIKKFSGDNNIIGITPFCIETIDKKCDYHLRSIAPY
                     VGVTEDPVCGTGNACVSSYIVHHNILDKTSFIGEQGNFINRPGKVYVNITRENNDITS
                     VKIGGSAYTILSGEIMY"
     gene            complement(4312..5667)
                     /locus_tag="OE968_003504"
     CDS             complement(4312..5667)
                     /locus_tag="OE968_003504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HCP7220737.1"
                     /translation="MSSTVKKKGKFPMGFYICSTTFSFERAAYYASKYLIYIFLTTAI
                     VHGGLGIDKGQAAIMQANLVAFTYLAPIIGGYISDRWIGARYTIPIGMLIMGVGYYLG
                     SIATTVSMVNAMIILVSIGTAFFKGNVSAVNGQLFDSQEELDTAFSVQYSFVNIGSFI
                     GTIAVGILYLKTFAKNGVLGFSQCFFIAAVLCVIGAIWFIYGWRFLGNAGKRPFKEGV
                     VAEKIEEKDKSPLTSMDKKRIWAIILISFFSVIFWVFWYLTYLAVYDYGAAFVNMNVG
                     GFDVPLAWFDSLNSLVCIVLGPVLGALWFKLASRPQGDMSLFKKTGLGLIFLGLAFLM
                     LVGAEFSRGVGAPETAKASILWIIMFGILLSLGEMLFSPLGNSFVSKYAPKKLLGVLM
                     GVWTFATFIAGKGYGYIYAFTLKFDMIKVYTIIPVILFVAAILLFLSDKTLSRLVEDD
                     K"
BASE COUNT         2587 a          953 c          834 g         2327 t
ORIGIN      
        1 aaaatctttt tttctaatta tatacaatat attttccatt atgttctaat caatttcttt
       61 actattttta caactttatt agtcatattc ataattattt ctaattagtg tttaacattt
      121 tatgtaaaat ttataaaaaa atgtatataa attaaaataa gtgactatac taaaaatatg
      181 atacggataa acaataagtt caacctatct cccccaaaat caagtgagct acagtttccc
      241 ccaactgtag ctcattttcg tgtaatttaa taaacatctc aacaagaatt aattaacaaa
      301 accccttata aaaacataac atatattaaa caagctcttg attaaaactt gagctttttt
      361 aataaaaaac agaatagttt attagataag gggttttttt atgcaattca tggatgtatc
      421 taaatacatt gaaggtgcaa accttaaagt taaaactaaa aatggtgaaa ctgttaaaag
      481 aatatatttt aacaactctg ccactccatt agttttaaaa aacgtagtgg ataacttaaa
      541 ctgtgagatt ccttggctta cttatattaa tgctccagga ataatctcag aaaaaaatac
      601 tttaaaatat gaaaatgtac gctctactat cctcaaactt attgatggag acgaagaaaa
      661 ggattctgtt atttatgtca aaaatgctac agaaggaata aacttcttag caaaattttt
      721 taaagatgaa aatccagata aatttgttat taccacagca atggagcata tggctaatta
      781 cctgcctttt aaagttaatt ttcctacaaa agttgttgga attacagaaa aaggagaact
      841 tgatttatgt caattagaga atatacttaa aaattatgct ggtaatgtat ctctcgttac
      901 agttacagga gctagtaatg tcacaggtat aaccactcct atatatgaaa tagcaagaat
      961 agctcataag tatggtgcaa agatattggt ggatattgtg caagtaattc agcataaacc
     1021 tttttcaatg atgccacatg aatgtgatga gcatatagat tttgttgttt ttagtgctca
     1081 taaatgttat tctccactaa atggaggagc tctggtagga cctaaaaaat tctttgaaaa
     1141 atttaatcct gtactatatg gctcaggttc taccaaattt gtaaatgata acaaaatact
     1201 atatgcaaac gtaccccaac gttttgaagc aggataccca gagtattttg gaactcttgc
     1261 aatgggaaaa gcactgaaca ctttaaataa aattggtcta aacagaattt caaaatacga
     1321 aagagaatta tttttatatg ctaaagaaga aatgagtaaa atacctaata taataatata
     1381 tggagataaa tcaaataatg taattatccc aaatatatct tttaatataa gtaatatgta
     1441 ttacaaagat gtagcaaaat atttagttga taactttgga atagaaactg gagctggagt
     1501 agtaggtgca gatatttatg tacaaaaatt attaggtata aatccaaaag aggcatacgt
     1561 cagatttatg agggaaaatc ctgtaggtct tgttaggata agcttaggaa tgtacaatac
     1621 ttttgatgag gtggatagct ttatacatgc tattaaaact ttggctttta aataagattt
     1681 ttctattctt ttttatcaat aaatagagag tagttttgtt ttcacaaaaa aacaaattat
     1741 atcaacagtc aatttcatta gcaattagac actcatttgt aactatacaa actattttac
     1801 actatacaaa caaaaaactc attacaatga gtttttttgt ttatatatga gatttatttt
     1861 aattacttca atttacttta attacatata tgattcaatt ttgtttttta aattctcctt
     1921 aggcataaaa cctattaatc tatctacagg ttttccatcc ttaaatatta gcatagttgg
     1981 tactgtagat acttcaaatt tctgagctaa ttctatactt tggtctatgt ccaccttcaa
     2041 gaagtttgct ttttcaacca tctcatttcc taaagcttca tatattggtg atagcatctt
     2101 acaaggtcca caccaagtcg caaagaaatc tacaactact aaaccatctt tattttctac
     2161 ttcatttata aattcattat tatttattat ttttaccata atatacatct cctttattat
     2221 cttcttgata ttaatatact acgccctata taacagttca attaggcact tttttgtaac
     2281 cgcctatttt taatagattt aatattatga taaatagatt tataagatta aatatttatg
     2341 agactaaata tttctaatat attttatttt tttcttaata tagttgacat tttttccctt
     2401 aaattataaa atcaaattaa taactacata ggtagttact aatcttttat caaaggagtt
     2461 tctatatgga taatataatt aatgaattac aaaatatagg atttactaaa tacgaatctc
     2521 aaatatacat atcattatta aaggaaagcc ctttaacagg atatgaaata agtaaattat
     2581 caggtgtacc acaatcaaaa gtctatgaaa atataacaaa gctattaaac aataatataa
     2641 ttatcaatgt tggaactgac cctattaagt acataccaat aaaccctaat gaattattaa
     2701 aaaataagaa aaaagaattt gacaattcta tggataatct aaagaatagc ttacagatat
     2761 taaataaaag taaaagtgta gaatacgtat taaacataaa aggagataaa aatatattaa
     2821 aaaaagcaat agaaatgata aaaaatgcaa aacaagaaat tataatttct tgcccttatg
     2881 aagaaattct tgaattaaaa aaagaactcc taattgctta caaaaaaaat attaatattg
     2941 aaatactact tttagaaaac aaaagtctga aaggtcttga taatattcat attcatggag
     3001 gtaataaaac tacacttgaa aataaaatgc tttacaaagg aattattttg attgtagata
     3061 atgatgaaat attgacagga aacttatcag aaggcagtga ggccatttca atttggacaa
     3121 aaaactctaa cattttatat attggagttc aatacataaa acatgaaatt tatatttcag
     3181 aacaaataaa aggaggttat aaaaatgaac aaaattaaga ttaaacaagt tgatgctttt
     3241 acaactatac cttttggtgg aaatcctgct ggtgtcgtta ctgatgcctc taacatttct
     3301 gatgaaatta agcagaatgt ggctaaagaa atgaatttat cagaaactgc atttgtttca
     3361 gagtcaaata ttgcagattt taaagtacaa tttttcacac caggtttaga agttgattta
     3421 tgtggtcatg caacaatagg tactttccat gcacttttgg aagaagggaa gcttaatact
     3481 aataagagta tattttatca agaaacaaaa gctggtgtat tatctgtaga gcttaagaaa
     3541 ataaataatg aaaatatatt tatgatggaa cagaatacac ctgaatttga aaatttagat
     3601 aattgcagaa aagaacttgc acaaatgata ggtgtgcatg aagatagact tcttgaatat
     3661 cctattataa aggtaaatac tggactttgg tggcttgtat ttggtctaaa atctttagat
     3721 gatttaaaaa atatctctcc agatttaaat aaaatcaaaa aatttagtgg tgataataat
     3781 ataattggta taactccatt ttgtatagaa actatagata aaaagtgtga ctaccattta
     3841 agatctatag caccatatgt tggagttaca gaagaccctg tatgtggaac tgggaacgct
     3901 tgcgtatcat cttatatagt acatcacaat attttagata aaactagttt tattggtgag
     3961 caaggtaact ttataaacag acctggaaag gtatatgtaa atataactag agaaaacaat
     4021 gacataactt ctgtaaaaat tggaggaagt gcttatacta ttttaagtgg tgaaattatg
     4081 tattaatccc atacctaata aaaacaaata aaaatactag ctaactaaag ctagtatttt
     4141 tatttgttat ttttatttaa taatcatact ctaacaaata ttataattat atatatcata
     4201 atattgtatt tagaagtaaa attttatttt tattattaat tagttataaa tcaatctaat
     4261 acaacataat tacagtagat taacctataa aacataataa ttgcttacta attatttatc
     4321 atcctcaaca agtctactta atgtcttatc agataagaat aataatatcg ctgcaacaaa
     4381 tagtattact ggaattatag tatatacttt aatcatatca aatttaagag taaatgcata
     4441 tatatatccg tatcctttac cagctataaa agtagcaaat gtccatactc ccataagaac
     4501 acctagaagc ttcttaggtg catacttact tacaaaagag ttaccaagtg gtgagaataa
     4561 catttcacca agacttaaaa gaataccaaa catgattatc catagtatac tagctttagc
     4621 agtttcagga gctccaaccc ctcttgaaaa ttctgcacca acaagcatta agaatgcaag
     4681 acctaagaat attaatccaa gacctgtctt tttaaataaa ctcatatctc cttgtggtct
     4741 actagcaagt ttaaaccata atgctccaag aactggtcct aatactatac atacaagtga
     4801 atttaatgag tcaaaccaag caagaggaac atcaaatcct ccaacattca tgtttacaaa
     4861 tgctgcacca taatcataaa ctgcaagata agttagatac cagaataccc agaaaattac
     4921 agagaagaat gatataagta taatagccca aattctcttc ttatccatgc ttgtaagagg
     4981 agacttatct ttttcttcaa ttttttcagc aactacacct tctttaaaag gtctctttcc
     5041 tgcattccca aggaatctcc atccatatat gaaccatatt gcacctatta cacaaagtac
     5101 agctgctata aagaaacatt gagaaaatcc aagtacacca ttttttgcaa atgttttaag
     5161 gtaaagaata ccaactgcta tagtaccaat aaaagaacct atattaacaa aagaatactg
     5221 tactgaaaat gctgtatcaa gttcttcttg actatcaaaa agctgtccat ttaccgcaga
     5281 tacgttacct ttaaagaatg cagtaccaat tgaaactaag attatcattg catttaccat
     5341 agaaactgta gttgcaatag aaccaagata gtatcctact cccatgataa gcatacctat
     5401 aggtatagta tatctagctc ctatccatct atctgatata tatcccccaa ttataggtgc
     5461 aaggtatgtg aatgcaacaa ggttggcttg cattatagca gcttgtcctt tatctattcc
     5521 aagaccacca tgaactatag ctgttgtaag gaatatatat attaagtact ttgaagcata
     5581 atatgctgct ctttcaaatg agaaagttgt tgagcagata taaaatccca taggaaattt
     5641 acccttcttt tttactgttg agctcataat tttaaatcct ttcttaattg tatttttatt
     5701 ttttacgttt tgtccaaatt ctttctttta tgaaagatat aatattatta ttttgtaaaa
     5761 caatttgtaa ttattattaa gataattgcg catttatttg tagagtacat attctcatgg
     5821 aataaaatta atacacttct taatcataaa tttaaattat ataaattcac tattttcaga
     5881 tatagttata aattaatata ttctcatcta ataccatgaa aaaaccttcg ccatatgcaa
     5941 ttcttatttt ttacgtgata gtattttaca aactaaaatc ccccttttgt agcaacttat
     6001 gtaattacat tttagtgctt ttttaaagga gtctcgaata aagcaacata tattttgttc
     6061 aaataatgtt tttatttatt ttttaaattt atatattact tcactcaacc aattctcaac
     6121 ttaaataact aaactactat ctattcacag attaggctta tttcttacac attagtttat
     6181 aataaacact gtgaatctaa acataaaaac tgttatttta aagtaattac ccatatattc
     6241 gctttgatac tatttattga ggttatactc tttatgtata atatattatt tataaaatac
     6301 ctcaaaatat attattcata aaatacctca aactgaaaac tttttcacga atatttattt
     6361 ttcacctccc cttttttatt tcaccatgta aatcgtacca taaatatgca cttatatgca
     6421 agaaaaaaat ctattaatcg acagtaaata attagaaaaa ttcaaattat atttatcaag
     6481 tatattatat aaaatatttc ctatgaaaat ataaattaaa ttaatgttca gaattgtttt
     6541 tagatatgaa atcttgattt ttttattact ttacttattt gctcaaatat atttttgtat
     6601 gcagtatata ataatcaaat tatacacttc ttataactgc attgatttga aaataatatt
     6661 aataattaat agaataaaaa atttaaatta aatttaaaaa a
//
LOCUS       DAJMZY010000153         6447 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.157, whole genome shotgun sequence.
ACCESSION   DAJMZY010000153 DAJMZY010000000
VERSION     DAJMZY010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6447)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6447)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6447
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.157"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            320..778
                     /locus_tag="OE968_003505"
     CDS             320..778
                     /locus_tag="OE968_003505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HCP7220738.1"
                     /translation="MEFINFVSDKVIDLKMDCKTKEDFFKEIHNKVFDLGFVKEEFGE
                     KILARENVFPTGLNLGDYGVAIPHTDAEYIKEQFISVCTFNEPVVFSSMEDQDEKVPV
                     NLAFVLGLNQPHSQLSVLTELMGIMQNKELVDKLMSSTDKEEVLKTLKSL"
     gene            839..1114
                     /locus_tag="OE968_003506"
     CDS             839..1114
                     /locus_tag="OE968_003506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCP7220739.1"
                     /translation="MKKILVACGAGIATSTVVCDKVERLVKENNIQAEVIQCKIAECA
                     TKQEGADLIVSTTILPTTYNIPAIKATAYITGVNTAALDKKILDALK"
     gene            1173..2447
                     /locus_tag="OE968_003507"
     CDS             1173..2447
                     /locus_tag="OE968_003507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012951111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HCP7220740.1"
                     /translation="MDKLLAVVQYILNMGPTVILPITIVVLGMIFRIKFTKALKSGLT
                     IGIGFVGINLVVNLLTSTLGPAAQGMVERFGLNLTVIDVGWPTTASATWASPVAPILI
                     PVCLLVNLLLLYFNKTKILNVDIWNYWHFIVAGAVGYIVTGSYVWAIFCAILMELLVL
                     FIAEKTAKNVQEFYDLEGIALPTGSTASFAPLGYLVGKFVEKIPGINKIQADPDSIQK
                     RFGIFGEPMMMGIILGIILGALAGYDVAGIFNVGISMGAVMLLMPRMVRILMEGLIPI
                     SESIRDFLQAKYGDRELYIGLDAAVATGHPAVISTALILVPITLFLAVILPGNKVLPF
                     GDLATIPFYMAFIVCFRKGNIVQSVITGTIVIAISLYMATNFADVHTQLLQQANMMPE
                     GTTMVTSIDTGGNLLKWGILKLSQLVSSFGIF"
     gene            2577..3629
                     /locus_tag="OE968_003508"
     CDS             2577..3629
                     /locus_tag="OE968_003508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HCP7220741.1"
                     /translation="MKAAVLHGTNDMRFEDIEIKPCESDEVKIKVMAAGICGSDPPRV
                     LKHWKYPVPAIPGHEFSGVIAEVGKDVKNVKVGDRVVAIPFIPCNECEYCKRGLFSLC
                     DDHGMLGAKSFGAFAEYVNIKATNVLPIGDMNFEDAAMIEPLAVAMHGVLNIGVQVGD
                     TVAVMGSGTMGQLVIQGLKIAGAGTIIAVDISDNKLRESKELGADIIINAKDINPVEK
                     IKELTGGKGVDIALECAGSKITQEQCLLITKKKSKIGFLGIAYSDITLSEEAFENIFR
                     KELELKGFWNSYSAPFPGQEWTKGINLVNEGKIKLKEMVSHRFSLEDTYKAFEMIRDR
                     KEEFNKILILPQGVEK"
     gene            3629..4660
                     /locus_tag="OE968_003509"
     CDS             3629..4660
                     /locus_tag="OE968_003509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012986518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding dehydrogenase"
                     /protein_id="HCP7220742.1"
                     /translation="MKAVVKTKPGYDNVEVLEVEEPKATGDKVKIKVEYSGICGSDIH
                     SFKGEYANIKAPVTLGHEFSGIVVEVGEDVKNIKVGDRVTSETTFATCEKCIYCETKD
                     YNLCPTRKGIGTQVNGSFAEYVLSREESIHVLPENVSLLSAALTEPLACCVHAALEKT
                     TIESSDTVLIIGPGPIGLLLAQVVKSQGATVIMSGVTKDKERLEIAKNLGVDRTVNVM
                     EESLADVVNEMTDGNGVNKGFDCSGFMPAVNEALRLLRKKGTFVQVGIFAKKLNEMDQ
                     EAIIQRELQYIGSRSQKPSSWITALDLMANGKVNTEALVTRTVGLDEFKEGITALMNG
                     EEIKVAVKS"
     gene            4752..5564
                     /locus_tag="OE968_003510"
     CDS             4752..5564
                     /locus_tag="OE968_003510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HCP7220743.1"
                     /translation="MSTLRDHSNNIRKNIIKMVAEAKSGHPGGSLSIADMLTVLYFDK
                     MNVCAENPKMADRDRFVLSKGHAAPALYATLAEKGFFPEEELITLRKFGSKLQGHPDM
                     KKVAGIDMSTGSLGQGLSAANGMALAGKLDNKDYTVYTILGDGEIQEGQIWEAAMTAS
                     HYKLDNLIAFVDLNGLQIDGSNEEVMNVSPVDDKFKSFGWNVIVINGHSFEEIGNAVD
                     EAKKVTGKPTVIIAKTVKGKGVSFMENNAAWHGTAPNAEQAEQALKDLEGGL"
     gene            5567..>6447
                     /locus_tag="OE968_003511"
     CDS             5567..>6447
                     /locus_tag="OE968_003511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HCP7220744.1"
                     /translation="MGIATREAYGQVLKELAENKDIVVLDADLGKATKSISFKEVAPD
                     RFFDMGIAEGDMIGTAAGLATCGKIPFASTFAIFAAGRGYEQIRNSVAYPNLNVKIAA
                     THAGVTVGEDGGSHQAIEDISLMRGIPNMVVLNPADALEARQAILTSIDYNGPVYIRL
                     GRAATPDVNSENYKFEIGKGTVLREGSDITVIATGIMVAKALEAAEELAKEGINVEVV
                     NISTIKPLDEALIKETAKKTGKVVTAEEHSIIGGLGSAVCEALAETKDVVVRRIGVKD
                     VFGQSGTPADLLKHYGLT"
BASE COUNT         2592 a          755 c         1264 g         1836 t
ORIGIN      
        1 cataataaat aattttataa aatagttgtt aaacataaaa aaccatttgt aaaaaacaaa
       61 aaaatcattt ctctaacaaa aaaaaccaca aaaaatataa aaaagtatgg ctagttaagt
      121 gattaacaag taaaaattaa aataaaaatc aaaaaaaatt tatcaatgaa agtcagctaa
      181 aatcctggaa gagagcatta tttttgggaa aacattttct tttgtttcac aaaaaaagcc
      241 actttttggc acacaacatg ctttatataa agtcaagaaa aactaaggta taagacaaag
      301 gcaattagga ggtgtaaata tggagtttat aaattttgta agtgataaag ttatagacct
      361 taaaatggat tgtaaaacga aagaagattt ctttaaagaa atacataata aagtttttga
      421 tttaggcttt gtaaaagaag aatttggaga aaaaatatta gcaagagaaa atgtatttcc
      481 aacaggttta aatttaggag attatggagt agcaatacca catacagatg cagaatatat
      541 taaagagcaa tttatatcag tctgtacttt taatgaacca gtagtgttta gttctatgga
      601 agaccaagat gaaaaagtac ctgtaaattt ggctttcgta ttaggactta atcaaccaca
      661 cagtcaatta tctgtattaa cagaattaat gggaattatg caaaataaag agttagttga
      721 taagttgatg agttctactg ataaagaaga agttttaaag acactaaagt ctttataaaa
      781 ataaaaaagt actaaaaata aaaaatataa aaataaaaat tattaggagg aaataaaaat
      841 gaaaaaaata ttagtagcat gtggagcagg aatagcaaca tcaacagtag tttgtgacaa
      901 ggtagagaga ttagttaagg aaaataatat acaagcagaa gttatacaat gcaaaatagc
      961 tgaatgtgca acaaagcaag aaggagcaga tttaatagta tcaacaacta tactaccaac
     1021 aacttataat ataccagcaa taaaagcaac agcatatata actggagtaa atacagcagc
     1081 attagataaa aaaatattag atgctttaaa ataatcctat catagataca ttgaaataat
     1141 attttataaa acagaaaaag gaggatttat aaatggataa attattagca gtagtacaat
     1201 acattttaaa tatgggaccg acagtaatac taccaataac aattgtagta ctaggaatga
     1261 tatttagaat taagtttaca aaagctttaa agtcaggtct tacaattggt ataggatttg
     1321 tgggtataaa cttagttgta aacctattaa catcaacact agggccagcg gctcaaggaa
     1381 tggttgaaag attcggactt aatttaacag taatagatgt tggttggcca acaacagcat
     1441 cagcaacatg ggcttcacca gttgcaccaa tattaatacc agtttgttta ttagtaaact
     1501 tactattatt atacttcaat aaaacaaaga tattaaacgt tgatatatgg aattattggc
     1561 actttatagt agcaggtgca gttggatata tagtaacagg aagttatgtt tgggctatat
     1621 tctgtgcaat actaatggag ttattagtac tgtttattgc agaaaagaca gcaaaaaatg
     1681 ttcaggagtt ttatgattta gaaggtatag cattaccaac tggttcaaca gcttcatttg
     1741 ctccacttgg atatttagta ggtaaatttg ttgaaaaaat accaggaata aataaaatac
     1801 aagcagaccc agactctata caaaaaagat ttggtatatt tggagaacca atgatgatgg
     1861 ggattatact aggtataata cttggagcac ttgcgggata tgatgtagca ggaatattca
     1921 atgtaggtat atcaatgggt gcagtaatgt tacttatgcc tagaatggtt agaatattaa
     1981 tggaaggttt aattccaatt tcagaatcaa taagagattt cttacaagca aaatatggag
     2041 acagagaact ttatataggt ctggatgcag cagtagcaac tggacatcca gcagttatat
     2101 caacagctct tatacttgtt cctataactt tgttcttagc agttatacta ccaggaaaca
     2161 aagttttacc atttggagac ttagcgacaa taccatttta tatggcattt atagtgtgtt
     2221 ttagaaaagg taatatagtt caatcagtta taacaggaac aatagtaata gctatatcac
     2281 tttatatggc tacaaacttt gcagatgttc atacacaatt attacaacaa gcaaatatga
     2341 tgccagaagg aacaacaatg gttacaagta tagatacagg tggaaacttg ctaaaatggg
     2401 gaatattgaa attatctcaa ttagtttctt catttggaat attctagtat gtagttaata
     2461 gagattactc ttttttagta aagtatgcga aaatttaaca tttagcagct actaaaaaag
     2521 agtaatattt tttataaatt tttaaaaata caaaatacaa gaggaggaga tttatcgtga
     2581 aagcagcagt attacatggc acaaatgata tgagatttga agatatagaa ataaaaccat
     2641 gtgaaagtga tgaagtaaaa ataaaagtta tggcagcagg aatatgtggg tcagatcctc
     2701 caagagtatt aaaacattgg aaatatccag ttccagctat accaggacat gagttttctg
     2761 gagtaattgc tgaagttggt aaggatgtaa aaaatgtaaa agttggagat agagtagttg
     2821 caattccttt tataccttgt aatgaatgtg aatattgtaa aagaggatta ttttcattgt
     2881 gtgatgacca tggaatgtta ggagctaaaa gttttggagc ttttgcagag tatgtaaata
     2941 taaaagctac aaatgtactt ccaataggag atatgaactt tgaagatgct gcaatgatag
     3001 agccactagc agttgctatg catggagtac ttaatatagg tgttcaagtt ggagacactg
     3061 tagctgtaat gggtagtgga acaatggggc agttggtaat acaaggactt aaaatagcag
     3121 gggcaggaac aattatagca gttgatatat ctgataataa attaagagaa tcaaaggaat
     3181 taggggctga tataataatt aatgctaaag atattaaccc agtagaaaaa ataaaagaac
     3241 ttactggtgg aaaaggtgtt gacatagctc ttgaatgtgc aggttcaaaa ataactcaag
     3301 aacaatgttt acttataact aaaaagaaaa gtaagatagg atttttaggg atagcatatt
     3361 cagatataac tttatcagaa gaagcatttg aaaatatatt tagaaaagaa ctagaattaa
     3421 aaggtttttg gaactcttat tctgcaccat ttccaggaca agaatggact aagggaatca
     3481 atctagttaa tgaaggaaag ataaaattaa aagaaatggt atctcataga ttctcacttg
     3541 aagatactta caaagcattt gaaatgataa gagatagaaa agaagaattt aacaaaatat
     3601 taattttacc acaaggggtt gaaaaataat gaaagcagta gttaaaacta aaccaggcta
     3661 tgataatgta gaagttttag aagtagaaga accaaaagct acaggagaca aggttaaaat
     3721 aaaagtagaa tatagtggta tatgtggttc agatatacat tcatttaaag gtgaatatgc
     3781 aaatataaaa gccccagtaa cattaggtca tgaattttct ggaattgttg tagaagtagg
     3841 agaagatgtt aaaaatataa aagtagggga tagagttaca tcagagacta cttttgcaac
     3901 ttgtgagaaa tgtatatatt gtgaaactaa agattataac ttatgcccaa ctagaaaagg
     3961 tattggtact caagtaaatg gaagttttgc tgagtatgta ttatcaagag aagaaagcat
     4021 acatgtactt cctgaaaatg tatctttatt atcagcagcc cttacagagc cactagcttg
     4081 ttgtgttcat gcagctcttg aaaagactac tatagaaagt tctgatacag ttttaataat
     4141 aggaccagga ccaattggtt tattattagc tcaagttgtt aaatctcaag gtgctacagt
     4201 tataatgtct ggtgttacaa aagataagga aagattagaa atagctaaaa atcttggagt
     4261 agatagaact gtaaatgtaa tggaagaaag tttggcagat gtagtgaatg aaatgactga
     4321 tggaaatgga gtaaacaaag gatttgattg ttctgggttt atgccagcag ttaacgaagc
     4381 cttaagactg cttagaaaaa aaggtacttt cgtacaagtt ggaatctttg ctaaaaaatt
     4441 aaatgaaatg gaccaagaag caataatcca aagagagtta caatatatag gaagcaggtc
     4501 tcaaaagcca agttcttgga ttacagcatt agatttaatg gcaaatggga aagtaaatac
     4561 agaagcttta gttactagaa ctgttggttt agacgaattt aaagaaggta ttacagcttt
     4621 aatgaacggg gaagaaataa aagtagcagt aaaatcttaa aaaaacattt gtattatttt
     4681 aaaaaaaatt gtaaaatcta ctgtaggata aaaaaatgta aggtcttaaa aaataacagg
     4741 aggaagaaag tatgagcact cttagagatc attctaataa tattagaaaa aacataataa
     4801 aaatggttgc agaagctaaa agcggacatc caggtggttc attatcaata gctgatatgt
     4861 tgacagtatt atattttgat aagatgaacg tatgtgcaga aaatccaaaa atggctgata
     4921 gagatagatt tgttctatca aaaggtcatg cagcaccagc tttatatgct acattagcag
     4981 aaaaaggatt tttcccagaa gaagaattaa taacactaag aaaatttggt tctaagttac
     5041 aaggtcaccc agacatgaaa aaagtagcag gaatcgatat gtctactggt tctcttggtc
     5101 aagggctatc tgcagcaaat ggtatggcac ttgcaggaaa attagataac aaagactata
     5161 cagtatatac tatattaggt gatggagaaa tccaagaagg tcaaatatgg gaagctgcaa
     5221 tgacagcatc acattacaaa ttagataatt taattgcatt tgttgactta aatggattac
     5281 aaatagatgg ttctaatgaa gaagtaatga atgtaagtcc agtagatgac aaattcaaat
     5341 cttttggatg gaatgtaata gtaataaatg gacattcttt tgaagaaata ggaaatgcag
     5401 ttgatgaagc taaaaaagtt acaggaaaac caactgtaat aatagctaaa acagtaaaag
     5461 gtaaaggtgt ttcatttatg gaaaataatg ctgcatggca tggaacagct ccaaatgcag
     5521 aacaagcaga gcaagcattg aaagatttag aaggaggtct ataggaatgg gaatagcaac
     5581 tagagaagct tacggacaag tgttaaaaga acttgcagaa aataaagata tagtagtatt
     5641 agatgcagat ttaggaaaag ctacaaaaag tatatcattt aaagaagttg ccccagatag
     5701 attttttgac atggggatag cagaaggtga catgattggt acagcagcag gtcttgctac
     5761 ttgtggaaaa ataccttttg cgagtacttt tgcaatattt gcagcaggaa gaggctatga
     5821 gcaaataaga aactctgtag catatccaaa tttaaatgta aaaatagcag ctactcatgc
     5881 aggtgtaaca gtaggtgaag atggtggtag ccatcaagct atagaggata tatctctaat
     5941 gagaggtata ccaaatatgg ttgtattaaa tccagcagat gctttagaag caagacaagc
     6001 tattcttaca tctattgatt ataatggacc tgtttatata agattaggta gagctgcaac
     6061 tcctgatgta aacagtgaaa attataaatt tgaaatagga aaaggaactg ttttaagaga
     6121 aggttctgac ataacagtaa tagctacagg aataatggta gcaaaagcct tagaagcagc
     6181 agaagaactt gctaaagaag gtataaatgt agaagttgtt aatatatcta caataaaacc
     6241 attagatgaa gcattaataa aagaaactgc taagaaaact ggaaaagtag ttacagcaga
     6301 ggagcacagt ataataggtg gtttaggttc agctgtatgt gaagctttag cagaaactaa
     6361 agatgtagta gttagaagaa ttggtgttaa agatgtattt ggtcaatcag gtacaccagc
     6421 tgatttatta aaacactatg gtttaac
//
LOCUS       DAJMZY010000154         6441 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.158, whole genome shotgun sequence.
ACCESSION   DAJMZY010000154 DAJMZY010000000
VERSION     DAJMZY010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6441)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6441)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6441
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.158"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            21..1763
                     /locus_tag="OE968_003512"
     CDS             21..1763
                     /locus_tag="OE968_003512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M3"
                     /protein_id="HCP7220745.1"
                     /translation="MVKSKKKIFVFLILIAVFIIFASYIRNYTNDTKKDSVRGTIPFE
                     KMEYKRPNIQSICENINKCNDKLLTAKTAKEQLNLFNEVDKIYQDFYSTLTIAKIRNN
                     IDSSDEFYSKEYKYLMSKSVDVDMSYKDFQDRFVTSKFSKELEKELGKDTFNYLKNIG
                     KLNSKEVEGLLKKEQDLVVKYEDLLAKSTVSIDGIEVDFEEALSRPNLSPEEYVKIYS
                     DYLKKYNPIFGNIFLELIQTRTEIASKQGFKNYIDYAYMNLNKDYSQEEAKKFRQDVK
                     DYIVPLYREISSKPSDSSIYIKVYKNRSFRKFDKVLEDISPKLKESFDYMKKYDLYDY
                     SSGKNKSPGGYTTYINKYKAPFLFNTWDNSFLGVTSFAHEFGHFYNYYNSINLNNKMQ
                     PSIDVCEVHSTSLEILFYKYFDDFFGKQSEAIKKEHLSIVLNTIIDACLYDEFQEIIY
                     KNPYMSLNDINKLFFDLEEEYGVSNNILREKNAPFWILVSHNFQVPFYYLSYGLASDV
                     SLQIWQLSQEDYRKAVDVYMDFLNQNTDAGFKDVVEKVNLQLPFQNGNLEEISSTLYD
                     YFGIDNPLELKNAS"
     gene            complement(1927..2121)
                     /locus_tag="OE968_003513"
     CDS             complement(1927..2121)
                     /locus_tag="OE968_003513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220746.1"
                     /translation="MKIITIGSSLITVLLFLSTMVCGFWIKNNKVTDASSIKFHMNSA
                     IFTGIFLLISTILLIIYIKK"
     gene            complement(2118..2699)
                     /locus_tag="OE968_003514"
     CDS             complement(2118..2699)
                     /locus_tag="OE968_003514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCP7220747.1"
                     /translation="MKSNDKDARERIIEVTLNLLNEVDDIEEITVRKIAERANVGVGL
                     INYHFKTKDNLLSTAIGDVMSNIIAELYDDSVYTLRPIEDLKNLLKKLCDTGLHYEKV
                     LPFVLNQCITNGDMQAELDIVPMLRKIFGNKKDEMSLRIIALQIILPIQISALSTESF
                     QLYSGINIKNKYERDKFIDILIENIIGEDVDVR"
     gene            2867..3685
                     /locus_tag="OE968_003515"
     CDS             2867..3685
                     /locus_tag="OE968_003515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HCP7220748.1"
                     /translation="MFKIGDFSKLSKISIRMLRHYDEIGLLTPSHTNKTNGYRYYSAD
                     QLSTTNRIHALKDMGFGLYSIKEILTEYNDKESLIKYLNIHHSQVKEQLEDTQKKLLK
                     IETTIKRIGGNDIMKNYDVTIKNFAPKYMMTLRRVIPTYQDEGMLWHQVFLETKDQNV
                     QIEPPKYSKAVFYDTGYKEDYVDVEVQVAVSGKYKDTEHVKFKTVPSVTAATAIVNGN
                     FNQVADACEAIGNWISDNNYDVDGPMFNIYHVSPGNDSNPDNWVTEVCFPVKKK"
     gene            4360..5181
                     /locus_tag="OE968_003516"
     CDS             4360..5181
                     /locus_tag="OE968_003516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002572585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallohydrolase"
                     /protein_id="HCP7220749.1"
                     /translation="MKLKIVGSGGMSIIPSSFCKCKICEEARQKGGRYERLGPSLYID
                     DIKMLIDTPEDIAVACNRQKISEVKHISISHHDPDHVKGIRIVEKIGCDFITGENNPI
                     GFYALPEVIEDINRTNLDCLKYYGNVINCISINETSHVKINNFDIDLINNNPDRNITF
                     YVIKENEKKVIYACCNPKPFTHSDMYFDADVLIISLVSDDGILNDGTKLKDTPFKDEI
                     FTLDEIVEIKNYYRIKKIIITHIDEIWGKSYGYYSELEKKLDNIYFAYDGMEIIV"
     gene            complement(5491..6270)
                     /locus_tag="OE968_003517"
     CDS             complement(5491..6270)
                     /locus_tag="OE968_003517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HCP7220750.1"
                     /translation="MSYKKIAIITGANSGFGKEFLKLLINEEEITEIWAVARNKARLN
                     QLVDEFGSKVKIFSKDLSKIEEVKEIGTFLSKENVCIKYLINNAGFAKFCSYNDLSID
                     ESINMIDLNISAVVALGLICIPYMQKGSHIMNISSQASFQPLPYQNIYSSTKAFIRNY
                     TRALNVELKSKGINAIAVCPGWMSTNLFKRGIVVAEKGTKNFPGIVSPDIVAKKALKD
                     AKKNKDISVYGINTKSSHLLAKLLPQKMMMKVWLMQQHIKE"
BASE COUNT         2421 a          879 c          827 g         2314 t
ORIGIN      
        1 tccatgattg gaggattttt atggttaaat ccaagaagaa aatatttgtt tttctaattt
       61 taattgcagt ttttattata tttgcatcat acataagaaa ttatactaat gatacaaaaa
      121 aagattctgt tagaggaact attccttttg aaaaaatgga atataagcgt cctaatatac
      181 agtcaatttg cgaaaacatt aacaagtgta acgacaaact tttaacagct aaaacagcta
      241 aggaacaatt aaatttattt aatgaagttg ataaaattta tcaggatttt tacagtacac
      301 ttactatagc aaaaattaga aataacatag attcatcaga cgaattttac tctaaggaat
      361 ataagtatct tatgagtaaa tcagtagatg ttgacatgtc atacaaagac tttcaagata
      421 gatttgtaac ttctaaattc tctaaagaat tagaaaaaga acttggaaag gatacattta
      481 attatctaaa gaacattgga aaacttaatt ctaaagaagt tgaaggtttg cttaaaaaag
      541 agcaagacct agttgtaaaa tatgaagatt tattagctaa atctacagta tcaatagatg
      601 gtatagaggt agactttgaa gaagccttgt caagaccaaa tcttagccct gaagaatatg
      661 tgaaaattta ttcagattac ttaaaaaaat acaatcctat atttggtaac atattcttag
      721 aacttataca gacaagaact gaaatagcaa gtaagcaagg atttaagaat tatatagatt
      781 atgcctatat gaacctaaac aaagactatt ctcaagaaga agctaaaaaa tttagacaag
      841 atgtaaaaga ttacatagtt ccattatata gagagatttc atctaaacca tctgattctt
      901 ctatttatat taaagtatat aaaaatcgct catttaggaa gtttgataaa gtacttgaag
      961 atatatctcc aaaactaaaa gagagcttcg actatatgaa aaaatatgac ttgtacgatt
     1021 attcttctgg aaaaaacaaa tcacctggag gatatactac ttatataaat aaatataaag
     1081 cacctttctt gtttaataca tgggacaatt cttttttagg tgttactagt tttgctcatg
     1141 agtttggtca tttttataat tactacaaca gtattaactt aaataataag atgcaaccaa
     1201 gtatagatgt atgtgaagtt cattcaacat ctttagaaat tctattttat aaatattttg
     1261 atgatttttt tggtaaacaa tctgaagcta taaaaaaaga acacttatcg attgttttaa
     1321 atactattat tgatgcttgt ctttatgatg aatttcaaga aattatatac aagaatccat
     1381 atatgagtct aaatgatatc aataaattgt tttttgattt agaggaagaa tatggagttt
     1441 ccaataatat acttagagaa aaaaatgctc ctttttggat acttgtatct cataacttcc
     1501 aagttccttt ttattacttg agttatggtc ttgcatctga tgtatcactt cagatatggc
     1561 aattatcaca agaagattac agaaaagctg ttgatgtata tatggatttt ttaaatcaaa
     1621 atactgatgc tggatttaaa gatgtggtag aaaaggtaaa tttacaatta cctttccaaa
     1681 atggaaattt agaggaaata agctctactt tatatgatta ttttggtata gataatccac
     1741 ttgaactaaa aaatgcttct taatttctaa tactttatac tcactcttaa gatttagtat
     1801 tagattgaaa taagtgatat tttttcacac acaattaatg tttaataaaa ttatatggta
     1861 aagtatcaga aatttttaag actcttgtct ttataatttc tgatacttta tttattaata
     1921 atattattat ttttttatat atataattaa aaggattgtg gaaatcaata aaaatatccc
     1981 tgtaaaaata gcactattca tatggaactt aatagaactt gcatctgtta ccttattatt
     2041 cttaatccag aacccacaaa ccatagttga aagaaaaagt aaaacagtga taagacttga
     2101 accaatagtt ataattttca tcttacatca acatcctctc caataatatt ttctattaaa
     2161 atatcaatga atttatctcg ctcatattta ttctttatat ttataccact gtataactga
     2221 aatgattctg tagataaagc agaaatctgt attggtaaaa taatttgcag ggcaatgatt
     2281 cttagactca tttcatcttt tttatttcca aaaattttac gaagcatagg gacaatatca
     2341 agttctgctt gcatatctcc attggttata cattgattca atacaaaagg aagcactttt
     2401 tcataatgta atccagtatc acacaatttt tttaataaat tttttaaatc ttcaataggt
     2461 cttagagtat atacactatc gtcatatagc tctgctatta tatttgacat cacatctcct
     2521 atggcagtac tcaacaaatt atcctttgtt ttaaaatgat aatttattaa accaactcca
     2581 acatttgcac gctcagcaat ttttctaact gtaatctcct caatatcatc tacttcattt
     2641 aaaagattca atgtaacttc aattatacgt tctctagcat ctttatcatt acttttcata
     2701 atagacctcc aaaacaatta acattttcgg ttctgaacat gttcagtata atattttttt
     2761 catcatatgt caatataatt taattataat tttagttgac tctaacatta tgatatggtt
     2821 tatattaata ttaagctaaa agtaccttta taaaggagac aaaaacatgt ttaagatagg
     2881 cgatttttca aagctaagta aaattagtat tcgtatgtta cgtcattatg atgaaatagg
     2941 acttttaact ccttctcata cgaataaaac taatggatat agatactata gtgcagacca
     3001 actttctact acaaacagaa tccatgcact aaaagatatg ggctttggct tgtattctat
     3061 aaaagaaatt ttgacagaat ataacgataa agaaagtctc ataaaatatc taaatatcca
     3121 ccattctcaa gtaaaagaac aattagaaga tacacagaaa aaactattaa aaatagaaac
     3181 cactattaaa agaattggag gaaatgatat tatgaaaaat tatgatgtaa ctataaagaa
     3241 ttttgcacca aaatatatga tgacacttag aagggttata ccaacttacc aagacgaagg
     3301 aatgttatgg catcaagtat ttttagagac aaaagaccag aatgttcaaa ttgaaccccc
     3361 aaagtattct aaagcagttt tttatgatac tggatataaa gaagattatg tagatgttga
     3421 agtacaagtt gctgtatctg gaaagtataa agatactgaa catgttaaat ttaagactgt
     3481 tccaagtgtg actgctgcaa ctgcaattgt taatggaaat ttcaatcaag ttgcagacgc
     3541 ttgtgaggct attggtaatt ggatatcaga taataactat gatgtggatg gtcctatgtt
     3601 taatatttat catgtaagcc ctggcaacga tagtaatcct gataattggg taacagaggt
     3661 atgcttccca gttaaaaaga agtaattttt atattaattg gataatattt taatttgtta
     3721 gacaaattac ttttagtgtt atgtataaat acctacaatt tgattaggat attatcttaa
     3781 tttgttaaac aaattacttt tagtgttatg tataaatatc tacaatttaa ttaggatatt
     3841 atcttaattt gtcagataaa tcaattataa gattatatac tatccttata ctctagttaa
     3901 atatatttta atcactaata taaattagtt tttttaacaa aacaataaaa gagtaaagta
     3961 caaataattc ctttgtgctc tactcttttt aactttcttt agacaataat acaatgataa
     4021 atataaaaaa ttatatattc cattctatag aaatatgctc accaataaca tgtatgttgt
     4081 taatcaatat attatatcaa attatatcaa aattacataa accttatagg acaatcatat
     4141 cttattacaa gaaaaatgtc ttatccatat tgaataagtc attcagttca tatacaaagt
     4201 caatttcatt gagaaacatt taatatatgt ttataaaaat ttcatactat tctttcatat
     4261 ttacatgtga tataatttat taactcataa ttttgttaat cagttgtgat tgtagattat
     4321 ttatataatc taatatttta agaaggtggt gtaataactt tgaaattaaa aattgttggt
     4381 agtggcggta tgtcaattat tccaagttca ttttgcaaat gcaaaatatg tgaagaagcc
     4441 agacaaaaag gcggaagata tgaacgatta gggccaagtt tatatattga tgatataaaa
     4501 atgctgatag acacacctga agatattgca gtagcttgta acagacaaaa aatatcggaa
     4561 gtaaaacata tttcaatttc tcaccatgac ccagaccatg ttaagggtat tagaattgtc
     4621 gaaaaaatag gatgtgactt tatcacagga gaaaataatc caattggctt ttatgcgctt
     4681 cctgaagtaa ttgaagatat aaaccgaacg aatctcgatt gtcttaaata ttatggtaat
     4741 gttataaatt gcatttctat taatgaaact tcgcatgtaa agataaataa ttttgatatt
     4801 gatttgatta acaataaccc agacaggaat ataaccttct atgttatcaa agagaatgaa
     4861 aaaaaagtca tatatgcctg ctgtaatccc aagccattta ctcatagtga tatgtacttt
     4921 gatgctgatg ttttaataat aagtctagtt tctgatgatg gtatattaaa tgatggtaca
     4981 aaacttaaag acacaccatt taaagatgaa atatttactt tagatgagat tgttgaaatt
     5041 aaaaactatt atagaattaa aaagattatc attacacata ttgacgaaat atggggaaaa
     5101 tcatatggtt attacagtga attagaaaag aaacttgata acatttattt tgcatatgat
     5161 ggtatggaaa ttatagtcta aatcattaag taataagcat aatgcaaaat aagaaaactt
     5221 caatttaaca gtatagttaa actatgtaat atcaacatat ctcagttttt acaaaatatc
     5281 atagtattta tctttataaa atttcaagtc ctacatattt taatacttca atatctaaat
     5341 aaagtaaaat caaaaatata ttttatatac attatagacg gcttatcggc actagataag
     5401 ccgttttgtc acaattatta tttgctcaac aaaacttctc ataatatata acagattgaa
     5461 tctccaactg atacttaatt accgaaactc ttattcctta atatgttgtt gcattaacca
     5521 aaccttcatc atcatttttt gtggcaatag ttttgctaat aaatgactgg attttgtatt
     5581 tataccatac acagaaatat ccttattttt ctttgcatcc ttcaatgctt ttttggcaac
     5641 aatgtctgga gacactatgc ctgggaaatt ttttgtccct ttttcagcta caactatacc
     5701 tctcttaaat agatttgtac tcatccaacc tggacataca gcaattgcat ttatcccttt
     5761 actcttaagt tcaacattta atgctcttgt ataatttctt ataaacgctt tagttgaact
     5821 ataaatattt tgatatggca atggctggaa tgatgcttgt gaagaaatat tcatgatatg
     5881 gcttcccttt tgcatatatg gaatacatat aagtcccaat gctacaacag cactaatatt
     5941 taaatcaatc atattaatag attcatctat acttaaatca ttgtatgaac agaattttgc
     6001 aaaaccagca ttgtttataa ggtattttat acatacattt tctttactta aaaatgtacc
     6061 aatttctttt acttcttcta tttttgataa atcttttgaa aaaattttta ccttacttcc
     6121 aaattcatct actaattgat ttaatctcgc cttgtttctt gcaactgccc atatttctgt
     6181 tatttcttct tcatttatta ataactttag aaactcttta ccaaaaccac tattagcacc
     6241 cgttataatt gcaatcttct tataactcat aattattctc ctttaccata agtttatacg
     6301 ctcaaactgt aaacttattt tttacaaata aaacaccctc tattcagatg ttatattcat
     6361 attatttgag atattatatt tatatcattt tcaataattg ttatatagca taaaaaatag
     6421 tgttaatatt atagaatcgg t
//
LOCUS       DAJMZY010000155         6423 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.159, whole genome shotgun sequence.
ACCESSION   DAJMZY010000155 DAJMZY010000000
VERSION     DAJMZY010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6423)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6423)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6423
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.159"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            169..1494
                     /gene="cdeA"
                     /locus_tag="OE968_003518"
     CDS             169..1494
                     /gene="cdeA"
                     /locus_tag="OE968_003518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MATE transporter CdeA"
                     /protein_id="HCP7220751.1"
                     /translation="MENLFTRKFTTFEFLKFVSPAIISMIFISLYTIIDGIFVSTLVG
                     SDALASINIVLPIINLVCGFGIMMATGGGAIVSIRMGENRQDEANSTFSFIVLFSLIV
                     GILFTVISYFFIKEISILLGATDKLLPYCITYGKVMILCTPFYILKFIFEYFARTDGN
                     SKFSLFLSVIGGVTNIILDYVFIKYFGMGLLGAAVATAIGIILTCVLGIIYFLSNKST
                     LKLRKPKTDFRLIRDTMINGSSEMVTELSTGITTFLFNVVALKLAGENGLAALTIVLY
                     AHFLMTSVYLGFAAGVSPLISYNFGAENSDKLKETFKHSLKFIFISSLLVFIIALVFA
                     PFIVRVFVNPDNTVFKLALQGLKIFAFAFLFVGINIFASGFFTAFHNGKISAIISFSR
                     AFVFIIIGIIILPPMLNMTGLWLTVPFAEVITIFISILFIKKYKCRYKY"
     gene            complement(1589..2383)
                     /locus_tag="OE968_003519"
     CDS             complement(1589..2383)
                     /locus_tag="OE968_003519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCP7220752.1"
                     /translation="MNELKPYIKFFNKNTKLYIIIFMIVGIVMNILPVFILKIFGEAS
                     KTNLSTIVNPILTYITILLFVYGVNIANKDFSGALSIRADRKSCIKAIVIDLIILSFV
                     ISILGIVLIFLSKLFIEIITGYSIELSVLLKRDMIWTSISALIDPSTSSMPLTYLNYF
                     VQICINEICIGFIGVLLGAFTYRVRKVTSITILIGLPILMVIYIVNFATKNMHKMLLY
                     LEKIIYSFQNPFILFGTKVGIIVICIIFIILLLRKAPIKEYANDLL"
     gene            complement(2384..3259)
                     /locus_tag="OE968_003520"
     CDS             complement(2384..3259)
                     /locus_tag="OE968_003520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCP7220753.1"
                     /translation="MSSSIKIENLSHSFKKQNIFNNMSLNFEKNKIYGLLGKNGAGKT
                     TLLNIMVNQLIQNEGEIEILGKNPKEDIKVLEEVCIVREKEFYSPDFKVGQIFEFSSS
                     FYKSYDKGLEKELCKYFDLNTKKKYKQLSRGMKTILSNIIGICSNSAITIFDEPTIGL
                     DAVNRQEFYNIILDSYIKNPRTIIISTHLIDEIDDLLEHVIILNEGKIIIDEEIDVIK
                     QKAHYITGNKEELEKLECIKNIKPKKAFGNAVAYFYYGDFSENDEKILKNSNIDVGYI
                     GLQDMFVNMTKKEEL"
     gene            complement(3263..3631)
                     /locus_tag="OE968_003521"
     CDS             complement(3263..3631)
                     /locus_tag="OE968_003521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCP7220754.1"
                     /translation="MKLVLNNEEPIFIQIARAIEDEILSNGIKEEEQVPSTTELSKLY
                     KINPATVLKGINILVDKNILYKKRGIGMFVSDGAKTIIKEARKENFKHNFVKNLLQEA
                     NKLEINREELVDIIINFKED"
     gene            complement(3814..4473)
                     /gene="deoC"
                     /locus_tag="OE968_003522"
     CDS             complement(3814..4473)
                     /gene="deoC"
                     /locus_tag="OE968_003522"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HCP7220755.1"
                     /translation="MKHILKTVDHTILKATTTWEDIKILCDEAVDMSVASVCIPPSYV
                     KRASEYLKGKIKICTVIGFPLGYQTTATKVFEAKDAIENGADEVDMVVNISDIKNKDY
                     DNIGKEIKEIKKAIGDKVLKVIIETCYLDEDEKIKMCEIVTMSGSDFIKTSTGMGTGG
                     ATLEDIKLMKEHVGKNVKIKAAGGVKSISDAEKFIEAGAERLGTSSICKILKNEDTTD
                     Y"
     gene            complement(4509..5696)
                     /gene="murJ"
                     /locus_tag="OE968_003523"
     CDS             complement(4509..5696)
                     /gene="murJ"
                     /locus_tag="OE968_003523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein biosynthesis integral membrane protein
                     MurJ"
                     /protein_id="HCP7220756.1"
                     /translation="MKQEPCDFSHGRFRTGIIFIGITSVMSAFLQIKENFIVVGFGSI
                     PYNIVIIISIMLSTIFGPYILPIGAVVAMVVQLLFYMFFVKKTNYKYLYYLNFKDDSL
                     IKLLALLSPVFIGVAVNQVNSLVDTTLASTLVKGSIPALTYADRLNGFVTGTFTASIV
                     SVMYPMLSKLSAENNQKKFTSSVKSSINMIIISMIPISVASIFFATPVVRIIFERGAF
                     DARATQMTATALIFYAVGMTAFGLRDILGKVFYSLQDTKTPMVNGIISVGVNIVLDLV
                     LIKPMAHGGLALATSSSSIACILLLFLNLKRKVGYFGQDKIIKATLKSVVASLIMGVL
                     SYFTYKFIFGILGVGTFNEFVSLAISVIVGGGIYTLLMTIFKVEEVDMILNIAKRKLH
                     LKK"
     gene            complement(5773..>6423)
                     /locus_tag="OE968_003524"
     CDS             complement(5773..>6423)
                     /locus_tag="OE968_003524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCP7220757.1"
                     /translation="PSGRYYVSLCCTDVDIEVFENTNNQIGLDLGIKEFCISSCGEFI
                     ENPKYFKKSLNKLAKLQRELSRKTIGSLNRNKARLKVARLQEHIANQRNDFLQKLTTK
                     LIKENDIICIEDLQVKNMIKNHKLSRLISDVSWSEFIRQLEYKANWHGRQIVKVGKFF
                     ASSQICNKCGYKNEEVKNLNIREWICPSCNETHDRDINASRNILKEGLRLITIQNK"
BASE COUNT         2123 a         1010 c          702 g         2588 t
ORIGIN      
        1 cagttagatt ttactaatat aagtttatta attagcatta tactaattta tcttaatatg
       61 attttttgtt gattttaagc tgtttatcgt ataaataaaa tttttcttga ctatatagtt
      121 actatatagc ttattatata tagagagtaa taaaaggagg taaaatttat ggaaaattta
      181 tttacaagaa aattcactac ttttgaattt ctaaaatttg tttctcctgc aattatatcc
      241 atgatattta tatctttgta tacaataata gatggcatct ttgtatcgac attagttggt
      301 tctgatgctc ttgctagtat aaatattgta ctacctataa ttaaccttgt ttgtggattt
      361 ggaataatga tggcaactgg tggaggtgct atcgtttcta tacgtatggg tgaaaataga
      421 caggatgaag ccaactctac attttctttt atagttttgt tttcattgat tgttgggatt
      481 ttattcacag taatctcata tttctttatc aaagaaatat ctattttgct tggtgcaaca
      541 gataagttat taccatattg tataacttat ggtaaagtta tgattttatg tacaccattt
      601 tatattttaa aatttatatt tgagtacttt gcaagaactg atggaaattc taaatttagt
      661 ttatttctat cagtcattgg tggtgtaaca aatataatat tggattatgt atttattaaa
      721 tattttggaa tgggtctttt aggagctgca gttgcaactg ctataggtat tattttaact
      781 tgtgttttag gtattattta cttcttatct aataaatcta cactaaaatt aagaaaacca
      841 aaaaccgatt ttagacttat aagagatact atgataaacg gttcttctga aatggttaca
      901 gaattatcta caggaattac aacattctta tttaatgtag tagctttaaa attagcagga
      961 gaaaatggac ttgctgctct tactatagta ttgtatgctc attttttaat gacatcagtc
     1021 tatctaggat tcgctgctgg agtgtctcca ttaataagct ataattttgg tgctgaaaac
     1081 agtgataaat taaaagaaac atttaaacat tctctaaaat ttatatttat ttcttctctt
     1141 ttagtgttta ttattgcttt agtatttgca ccatttattg ttagggtctt tgtaaatcca
     1201 gataacacag tatttaaact agccttacaa ggattaaaaa tatttgcatt tgcttttttg
     1261 tttgttggta taaatatatt tgcatcagga ttttttacag catttcacaa tggaaaaatt
     1321 tcagctatta tatcttttag tcgtgccttt gtttttataa tcataggaat cataattctt
     1381 cctcctatgt taaacatgac tggattatgg cttacagttc catttgctga ggttataacc
     1441 atatttatat ctattctatt tataaaaaaa tataaatgta gatataagta ttaaaaatta
     1501 atacttaaaa tcaacattta ttaaaactaa taaacctgct ttaaaataca aatttacaaa
     1561 tttgattttt aagcaggttt tattttagtt ataataagtc atttgcatac tctttaattg
     1621 gtgcttttct aagtaataaa attataaata ttatgcaaat aactataatt cctacctttg
     1681 ttccaaataa aataaaagga ttctgaaatg aataaataat tttttctaaa tacaatagca
     1741 ttttatgcat atttttagtt gcaaaattaa ctatataaat taccattaat atcggtaatc
     1801 ctatcaatat agtaatacta gtaacttttc taactctata tgtaaaagct ccaagtaaca
     1861 ctcctataaa acctatacat atttcattta tacatatttg tacaaaataa tttaaataag
     1921 ttagtggcat acttgatgtt gaaggatcta tcagtgctga tatagatgtc caaatcatat
     1981 ctctctttag taaaactgat agttctatac tgtaacctgt tataatttct ataaataact
     2041 tcgataaaaa aatcaaaact atacctaaaa tagaaatcac aaagcttaaa ataattaaat
     2101 ctatgacaat agcttttata caactttttc tatctgctct tatacttaaa gctcctgaaa
     2161 agtctttatt tgctatattt actccataca caaatagcag tatagttata tatgttaaaa
     2221 taggattcac aatcgtggat aaattagttt tagatgcttc tccaaaaatc ttgagaataa
     2281 acactggcaa aatattcata acaattccca caatcataaa tataattata tacaatttag
     2341 tatttttatt aaaaaatttt atatatggct ttaattcatt caattacaat tcctccttct
     2401 tagtcatgtt aacaaacata tcttgtagcc ctatgtatcc tacatcaata tttgaatttt
     2461 taagtatttt ttcatcattt tcactaaaat caccatagta aaaataagca actgcatttc
     2521 caaatgcctt tttaggtttt atatttttta tacattctaa tttttctaac tcttctttat
     2581 ttccagtaat ataatgagct ttttgtttta tgacatcaat ttcttcatct ataataattt
     2641 ttccctcatt taatattatt acatgctcca gtaaatcatc tatttcatca atcaaatgag
     2701 ttgatattat tattgtcctt ggatttttta tataactatc taaaattatg ttataaaact
     2761 cttgtctatt tactgcatcc aaaccaattg ttggctcatc aaatatggtg atagctgaat
     2821 tagaacaaat acctattata tttgaaagta tagttttcat acctcttgac agttgtttat
     2881 actttttttt agtatttaaa tcaaaatatt tgcataattc tttttctaag cctttatcat
     2941 aacttttata aaaactagaa gaaaattcaa atatctgacc tactttaaaa tctggactat
     3001 aaaattcttt ttccctgaca atacaaactt cttccaaaac ttttatatct tcttttgggt
     3061 tctttcctaa tatttctatc tcaccttcat tttgaattaa ctgatttacc attatattta
     3121 ataatgttgt ttttccagct ccattcttac ctaataaacc atatatctta tttttttcaa
     3181 agtttagaga catattatta aaaatatttt gcttcttaaa actgtgagat aaattttcta
     3241 tcttaataga actactcata tattaatcct ccttgaaatt aattataata tcaaccaatt
     3301 cttctctatt tatttctaat ttgttagctt cttgaagtag gttttttaca aaattatgtt
     3361 taaaattttc ttttctagct tcttttataa tagtttttgc accatctgat acaaacatcc
     3421 ctatccccct cttcttatat aaaatatttt tatcaaccaa tatatttata ccttttaata
     3481 ctgtagctgg attaatttta taaagctttg aaagctctgt tgttgatgga acctgttctt
     3541 cttcttttat tccatttgat agtatctcat cttcaattgc tcgtgctatc tgaataaata
     3601 taggttcttc attatttaat actaatttca taggttcctc ctttctccat tagttagtta
     3661 ctcaactaat taactatata acttataata tcttgaaaaa tattttctgt caatactaaa
     3721 taaaaaacag agggaaaatt ccctctgttt tttgttcttt atatttataa ttaaattttg
     3781 atttttgtaa tcctatccca taagttaaaa actttaataa tctgttgtat cttcattttt
     3841 taatatttta catattgagc tagttcctaa cctttctgct cctgcctcta taaatttttc
     3901 tgcatcagaa attgatttaa ctccccctgc agcttttatt tttacatttt ttccaacatg
     3961 ctctttcata agctttatat cttctaaagt agctccacct gttcccattc cagtagatgt
     4021 ttttataaaa tctgaacctg acattgttac tatttcacac atttttattt tttcatcttc
     4081 atctaaataa catgtctcta taatgacttt taatacttta tctcctatag ctttttttat
     4141 ttcttttatt tcttttccta tattatcata atctttattt tttatatctg aaatgtttac
     4201 aaccatatca acttcatctg ctccattttc aatagcatct tttgcttcaa atacttttgt
     4261 agcagtagtt tgatatccca aagggaaccc tatcactgta catatcttta ttttaccttt
     4321 tagatattct gatgctcttt tcacatatga tggtggtatg caaactgatg ctacactcat
     4381 atctacagct tcatcacata aaattttaat atcttcccat gtagttgtag cttttaaaat
     4441 agtatggtct actgttttta atatatgttt cataaaatcc tcctaaattt ataattaata
     4501 taattagatt acttttttaa atgcaatttt ctctttgcaa tattcagtat catatcaacc
     4561 tcttcaactt taaaaatagt cattagtagt gtataaattc cacctccaac tataactgaa
     4621 atagctagtg agacaaactc attaaatgtt cctactccca aaattccaaa tataaattta
     4681 tacgtaaagt atgataaaac acccataatt aaagatgcaa ctaccgattt caaagttgct
     4741 tttattattt tatcttgtcc aaaatatcca acttttctct ttaggttcaa gaagagtaac
     4801 aatatacatg caattgatga tgaactagtt gcaagagcaa gaccaccatg agccattggt
     4861 tttattaaaa ctaagtccaa tactatattt acccctacag atataatccc atttaccata
     4921 ggtgtttttg tgtcttgtaa tgaataaaaa acctttccca aaatatctct taagccaaat
     4981 gcagtcatac caactgcata aaaaattaag gcagttgctg tcatttgggt tgccctcgca
     5041 tcaaaagcac ctctctcaaa aatgattcta acaacaggag ttgcaaaaaa aatagaagca
     5101 actgaaatag gaatcataga aattattatc atatttatac tagatttaac tgaactagta
     5161 aacttctttt gattattttc tgcacttaac ttagataaca taggatacat aacagatact
     5221 attgaagctg taaatgtccc tgtaacaaaa ccatttaatc tatctgcata agtaagtgct
     5281 ggaatgcttc ctttaactaa tgttgaggct aaagttgtat ctaccaatga gttcacttga
     5341 ttaacagcaa cacctataaa tactggtgaa agtaatgcta gtaatttaat aaggctatca
     5401 tctttaaagt ttaagtagta taagtatttg tagttcgttt ttttaacaaa aaacatgtaa
     5461 aagagcagtt gaactaccat agcaaccaca gcaccaattg gaagtatgta tggtccaaat
     5521 atggtactta acattattga aataattatt actatattat agggtatact tccaaatcca
     5581 actacaataa agttctcttt aatttgtaaa aatgctgaca taacacttgt aatacctatg
     5641 aatattattc ctgttctgaa cctcccatga ctaaagtcac agggttcctg cttcatagaa
     5701 ttttgcatac taaaatatgt cttactaatt ctccacaggc tatccccgta gttcctacgg
     5761 ttcttacata cgttatttat tttgaattgt tattagtctt aatccttctt ttaatatatt
     5821 tctacttgca tttatatctc tatcgtgagt ttcattacaa ctaggacaaa tccattctct
     5881 tatatttaag ttcttaactt cctcgttttt atacccacat ttattgcata tttgtgaact
     5941 tgcaaagaat ttacctacct ttacaatttg tctaccatgc caattagcct tgtattctaa
     6001 ttgacgaata aactctgacc atgatacatc agaaattaag cgagatagtt tatgattttt
     6061 aatcatattc tttacttgta aatcttctat gcaaataata tcattctctt ttattaattt
     6121 agtagttaat ttttgtagaa aatcatttct ttgattagct atatgttctt gaagtcttgc
     6181 aacttttaat cttgctttat ttctatttaa actaccgatt gtttttctcg ataattctct
     6241 ttgtaattta gcaagtttgt ttaatgactt cttaaaatac ttaggatttt ctataaattc
     6301 tccacaactt gagatacaaa attctttaat tcctaaatct aaacctatct gattgttagt
     6361 attttcaaat acttcaatat ctacatcagt acagcataat gatacataat atctaccact
     6421 tgg
//
LOCUS       DAJMZY010000156         6301 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.160, whole genome shotgun sequence.
ACCESSION   DAJMZY010000156 DAJMZY010000000
VERSION     DAJMZY010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6301)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6301)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6301
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.160"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            211..1149
                     /locus_tag="OE968_003525"
     CDS             211..1149
                     /locus_tag="OE968_003525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP phosphoribosyltransferase regulatory
                     subunit"
                     /protein_id="HCP7220758.1"
                     /translation="MKFLRIEDEVIYSKKRYKLKREIDKLFLDEEYFQIEPQLFEEYD
                     EFTTINNKIPEESMVKVVNGKVMVLRADITTSIIKSLVPRWEDGLKLKLFYNSSIYKN
                     TVGIKEIRQIGCEYLGEASVEADREVVKLALKILEKYNNNFILEVGSSKYIHGLLEEL
                     NLNKNCENQIKNLLYTKNTHELKVYIEELKIKREVKELLSNILSLQGNLYNVIEKSNK
                     FYCNNKMKQALEELKQVNNLIEECNFLDKARFDLSMITMLDYYEGIMFRGYYPNSYKE
                     ILSGGRYDSLTKEYGKEIPAIGFTLSVDELMKYVYK"
     gene            1171..1797
                     /locus_tag="OE968_003526"
     CDS             1171..1797
                     /locus_tag="OE968_003526"
                     /EC_number="2.4.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP phosphoribosyltransferase"
                     /protein_id="HCP7220759.1"
                     /translation="MDYLTIALAKGRIEGESFKKFKKMGLGDSIDTDTRKLIFKDEEN
                     KIIYIHVKPSDVVTYVEKGVADLGIAGKDTILENETDVYEIYDLGFGKCKFAVAGLKG
                     DSIYREDEYLKVATKYPNIAKKYFKEKGQKIEIIKLNGSVELAPIVGLSDVIVDIVET
                     GNTLKANGLEILEDICNISARIISNRASYRFKYEQIQNIIRLFEELDN"
     gene            1831..2880
                     /gene="hisC"
                     /locus_tag="OE968_003527"
     CDS             1831..2880
                     /gene="hisC"
                     /locus_tag="OE968_003527"
                     /EC_number="2.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate transaminase"
                     /protein_id="HCP7220760.1"
                     /translation="MREKESIRELKGYEPNHVNCKVKLDANEGSKRLFKYLIKEISDS
                     DIDLNLYPEDSYSDLKESIIDYINISGVNKKNLLVGNGSSEIIDLIIHTFVDKDEVIL
                     SFSPSFSMYSIYSQINGSKFIGVESDENLVINIDNVIEKVKENNPKIVIVCNPNNPTG
                     TILKREEIIKLLDSTNSLVVLDEAYMDFGEESMLSDVFKYDNLIVLRTLSKAFGLAGI
                     RTGYMLSNSSLINSVEKVRPPYNLNSLSDFIATRALRNKDVVKAYIKEVKEEREVLYK
                     EMIGMGIKAYKSQANFILFYSEIENLSQKLIDRGVLIRKFGGKLENYYRVTIGDKEEN
                     SMFVGAIRDILKKEK"
     gene            2883..3461
                     /gene="hisB"
                     /locus_tag="OE968_003528"
     CDS             2883..3461
                     /gene="hisB"
                     /locus_tag="OE968_003528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazoleglycerol-phosphate dehydratase HisB"
                     /protein_id="HCP7220761.1"
                     /translation="MRIWKVERNTLETQILVELNIDGSGKAEIDTGIGFLDHMLTLMS
                     FHGKFDLKVICKGDTYVDDHHSVEDIGIAIGEAFKNALGDKKGIRRYSNIYIPMDESL
                     SMVAIDISNRPYLVFNAKFDTQMIGSMSTQCFKEFFRAFVNESRVTLHINLLYGENDH
                     HKIESIFKAFARALKEGSEIVSNEIASSKGVL"
     gene            3463..4068
                     /gene="hisH"
                     /locus_tag="OE968_003529"
     CDS             3463..4068
                     /gene="hisH"
                     /locus_tag="OE968_003529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase subunit
                     HisH"
                     /protein_id="HCP7220762.1"
                     /translation="MNIIVDYGLGNIDSVSRGFRKAGIETKISSDIDEIKQADSLILP
                     GVGAFRDSISALDKLGLIPIIKEHVSKGKFMIGICLGMQLLYEKSYEYGEYEGLGLIK
                     GSIDKLDISLKVPHMGWNNLKFNKANDDILKYINEDDYVYFVHSYYANSSNEELIAFS
                     EYEKKIPAIVRKGNVYGIQFHPEKSGEVGLNILRAYGEMIK"
     gene            4065..4787
                     /gene="hisA"
                     /locus_tag="OE968_003530"
     CDS             4065..4787
                     /gene="hisA"
                     /locus_tag="OE968_003530"
                     /EC_number="5.3.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-(5-phosphoribosyl)-5-[(5-
                     phosphoribosylamino)methylideneamino]imidazole-4-
                     carboxamide isomerase"
                     /protein_id="HCP7220763.1"
                     /translation="MIIFPAIDIKDNKCVRLTQGEFDKVNVYYDNPLEVAYKWKNEGA
                     EYIHIVDLNGARSEFGVNTKIIEDIANNIDIPIQVGGGVRDKEKVKSLINAGVTRVIL
                     GSIAIENLNLVEELVNEYKEKIVVSIDAKDGKVAVRGWEVVSNVDSLTLCKQLEKIGV
                     QTIVYTDISKDGMLQGPNFDIYERIAKETSLNVIASGGVTSIEDVKRLKAMNLYGAII
                     GKALYDKKIDFKEAQQLCLLGE"
     gene            4769..5527
                     /gene="hisF"
                     /locus_tag="OE968_003531"
     CDS             4769..5527
                     /gene="hisF"
                     /locus_tag="OE968_003531"
                     /EC_number="4.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000880088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase subunit
                     HisF"
                     /protein_id="HCP7220764.1"
                     /translation="MLTRRIIPCLDVRNGRVVKGKKFKDIVDVDSPEVLGKFYSDCGA
                     DELVFYDITASNEERKTSLEFVTKVAENINIPFCVGGGVNKLEDFTDILRKGADKVSI
                     NSSAVKNPELIREASLKFGAQCVVLSIDAKKNEEGSWSVYVKGGREKTNLDAIEWAVK
                     GVELGAGEIVVNSMDEDGMKNGYDIELLSKITSLVNVPVIASGGAGKKEDFYEAVNKS
                     NVDGILAASVFHFGEIKINDLKKYLKDMGVEVRL"
     gene            5555..6223
                     /locus_tag="OE968_003532"
     CDS             5555..6223
                     /locus_tag="OE968_003532"
                     /EC_number="3.5.4.19"
                     /EC_number="3.6.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional phosphoribosyl-AMP
                     cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE"
                     /protein_id="HCP7220765.1"
                     /translation="MDNKCNNVYSDEVEKFIRSIKFDDKGLVPVVVQEVVSKDVLMLA
                     YMNKDAIKKTLKDKVACYFSRSRQELWVKGETSGNTQKVVKMSYDCDVDTILLFVEQT
                     GVACHTGNYSCFYRDLFDDSSKMELEVQTNILKELYDLINERKNNPVEGSYTNYLFEK
                     GIDKILKKVGEESSEVIIASKNTDKSELIYEISDLVYHTLVLMIEKGVEIDEIKKELL
                     KRRK"
BASE COUNT         2564 a          538 c         1247 g         1952 t
ORIGIN      
        1 aaatcatcac catcatcata gattaaaggg attgtaatat gaaattaatt catagacaca
       61 agccctgttt ttagtgtaat tggtcttgta tctatgatgg gaagtaattt taagagaaaa
      121 ttatagccat ataggtataa agcctatgtg gcttttttat tgttttaaat ttgcaaatat
      181 aagagtaaat ttaatgaaga gggtgagaat gtgaaatttt tgaggattga agatgaggtt
      241 atttattcta aaaaaagata taaattaaaa agggaaatag ataaactttt tttggatgaa
      301 gaatattttc aaatagaacc acaattattt gaagaatatg atgaatttac aactataaat
      361 aataaaattc cagaagaatc tatggtaaag gttgtaaatg gaaaagtaat ggtacttaga
      421 gctgatataa ctacaagtat aataaaaagc cttgtaccaa gatgggaaga tggtttaaag
      481 cttaagcttt tttataattc atcaatatat aaaaatacag ttggaataaa agagataaga
      541 caaataggtt gtgagtatct aggagaagcc tctgtagaag cagatagaga agtagtgaaa
      601 ttagctctta agatacttga aaaatacaat aataatttta ttctagaggt tgggagtagc
      661 aagtatattc atggtttgtt agaagaatta aatttaaata agaattgtga aaatcaaatt
      721 aaaaatttac tatatacgaa gaacactcat gaactaaaag tatatattga agaattaaaa
      781 attaagcgtg aagtaaaaga gttattatca aatattttaa gtttacaagg gaatttatat
      841 aatgttattg aaaaatcaaa caagttctat tgtaataata agatgaagca agctcttgaa
      901 gaattaaagc aagtaaataa cttgattgag gaatgtaatt ttttagataa ggctagattt
      961 gatttatcaa tgattactat gcttgactat tatgaaggaa ttatgtttag aggatactac
     1021 ccaaactcat ataaagaaat tcttagtggt ggaagatatg attctttaac taaagagtat
     1081 ggaaaagaaa ttccagccat tggatttaca ctaagtgttg atgagttaat gaagtatgta
     1141 tataagtaaa gtttagaagg agggattgct ttggattatt tgactatagc actagcaaaa
     1201 ggacgaattg aaggggaatc atttaaaaaa tttaaaaaaa tgggtctagg agacagtata
     1261 gacacagata cgagaaaact aatttttaaa gatgaagaaa ataaaattat atatatacat
     1321 gtaaagccat cagatgtagt tacatatgtt gaaaaaggag tcgctgacct cggtatagca
     1381 ggtaaagata ctattttaga gaatgagaca gatgtatatg aaatatatga tttaggtttt
     1441 ggaaaatgta aatttgctgt agcaggatta aagggagata gcatatatag agaagatgaa
     1501 tatttaaaag tggcaacaaa gtatcccaat atagcaaaaa agtattttaa agagaaaggt
     1561 caaaaaattg aaataataaa attaaatggt tctgtagaac tagctccaat agtagggttg
     1621 tcagatgtaa ttgtagatat agttgagact ggcaatacac ttaaagcaaa tggtcttgaa
     1681 atattagaag acatatgtaa tataagtgct agaattatat caaatagagc tagctataga
     1741 tttaaatatg aacaaattca gaatataatt cgtttatttg aagaacttga taattaaaat
     1801 ataattgagc tttataagga gggatttaag ttgagagaaa aagaaagcat aagagagtta
     1861 aagggatatg aaccaaatca cgtaaactgt aaagtaaaac ttgatgcaaa tgaaggaagt
     1921 aagaggttgt ttaaatacct tattaaagaa atttcagata gtgatataga tttaaattta
     1981 tatcctgaag attcttatag tgatttgaaa gaatctataa tagattacat aaatatttct
     2041 ggagtaaata agaaaaatct tctagtagga aacggttcaa gtgaaataat tgatttaata
     2101 atacatactt ttgtagataa agatgaagta atattgagtt tctctccaag ttttagtatg
     2161 tattctatat atagtcagat aaatgggtct aaatttatag gtgttgaaag tgatgaaaat
     2221 ttagttataa atatagataa tgtgattgaa aaagtaaagg agaataatcc taaaatagta
     2281 attgtatgta atcctaataa tccaactgga acaatattaa agagggaaga gataataaag
     2341 cttttagatt caactaatag tctagtggtt ttagatgaag catatatgga ttttggagaa
     2401 gaaagcatgt taagtgatgt ttttaagtat gataatctaa tagttcttag aactttatca
     2461 aaggcatttg gattggctgg aataagaaca ggatatatgt tatctaatag tagtttaata
     2521 aattctgttg agaaagtaag acctccatat aatttaaatt cattatcaga ctttattgct
     2581 acaagagcac ttagaaataa agatgtggta aaggcttata taaaggaagt aaaagaggaa
     2641 agagaagttt tatataaaga aatgattggt atgggaatta aagcatataa atcacaagca
     2701 aattttatat tattttattc tgaaatcgaa aatttatcac aaaaacttat tgatagaggt
     2761 gttttaataa gaaaatttgg tggaaagtta gaaaattatt acagagttac aattggtgat
     2821 aaagaagaaa attctatgtt tgttggagct ataagagata ttttgaaaaa ggagaaatag
     2881 gtatgagaat ttggaaggta gaaagaaata ctcttgaaac acagatttta gtagaattaa
     2941 atattgatgg ttctggtaaa gctgaaatag atactggaat aggattttta gaccatatgc
     3001 ttaccttaat gtcatttcat ggcaagttcg atttaaaagt gatttgtaag ggtgatacat
     3061 atgtagatga ccaccatagt gtagaagata taggtatagc tataggtgaa gcatttaaaa
     3121 atgctctagg tgacaaaaaa ggaatacgaa gatattctaa tatctatata cctatggatg
     3181 aatctctatc aatggtagca atagatataa gcaatagacc ttatcttgta tttaatgcta
     3241 aatttgatac ccaaatgatt ggtagtatga gtactcaatg ctttaaagaa ttttttagag
     3301 cttttgtaaa tgaatcgaga gtaacattac atatcaatct cttatatggg gaaaatgacc
     3361 atcataagat agaaagtatt tttaaagcat ttgcaagagc tttaaaagag ggtagtgaaa
     3421 tagtttctaa tgagatagca tcttcaaagg gggttttgta gaatgaatat aatagtagac
     3481 tatggtcttg gaaatataga ttctgtgtct aggggtttta gaaaagctgg aatagaaact
     3541 aaaatttcta gtgatataga tgaaataaaa caggcagatt cacttatact tccaggtgtt
     3601 ggagctttta gagattctat aagtgcctta gataaactag gattgatacc aataataaag
     3661 gagcatgttt ctaagggtaa atttatgata ggtatatgtc taggaatgca attactttat
     3721 gaaaaaagtt atgagtatgg agaatatgaa ggattaggac ttataaaagg aagtattgat
     3781 aaactggata taagtttaaa agtgccacat atgggatgga ataatctaaa atttaataag
     3841 gcaaatgatg atatacttaa atatataaat gaagatgatt atgtatactt cgttcactca
     3901 tattatgcaa attcatcaaa tgaagaacta attgcatttt cagaatatga aaagaaaatc
     3961 cctgctattg ttagaaaagg caatgtatat ggtatacaat ttcatcctga aaaaagtgga
     4021 gaagtagggt taaatatatt aagagcatat ggggagatga taaaatgata atatttccag
     4081 caatagatat aaaagataat aagtgtgtaa gacttacaca aggagaattt gacaaagtaa
     4141 atgtatatta tgataatcca ttagaagtag catataaatg gaaaaatgaa ggagcagaat
     4201 atatacatat agtagattta aatggtgcta gaagtgaatt tggtgtaaat acaaaaataa
     4261 ttgaggacat agcaaacaat atagatatac ctattcaagt tggcggtgga gttagggata
     4321 aggaaaaagt caaaagttta ataaatgctg gtgttactag agtaatatta ggtagtatag
     4381 cgattgaaaa tttgaattta gttgaagaat tggtcaatga atataaagag aaaattgtag
     4441 tttctataga tgctaaagat ggaaaagtag cagttagggg atgggaagtt gtaagcaatg
     4501 tagactcatt aacattatgc aaacaacttg aaaagatagg tgtacaaact attgtttata
     4561 cagatatatc aaaagatggg atgttgcaag gtccaaattt tgacatatat gaaagaatag
     4621 caaaggaaac atcactaaat gttattgctt ctggaggcgt aacttctata gaagacgtaa
     4681 aaagactaaa agctatgaac ttatatggtg caataatagg taaagcgctt tatgataaaa
     4741 agatagactt taaggaggca caacaattat gcttactagg agaataatac cttgtctaga
     4801 tgtgagaaat ggaagagtcg taaagggaaa aaaatttaaa gatatagtag atgttgatag
     4861 tccagaagta cttggaaaat tttatagtga ttgtggtgca gatgaacttg tattctatga
     4921 tataactgca tcaaatgaag agagaaagac atctttagaa tttgtgacaa aagttgcaga
     4981 aaatataaat ataccatttt gtgttggtgg aggagtaaat aaattagaag atttcactga
     5041 tattttaaga aaaggtgctg ataaagtttc tataaattca tcagcagtca aaaatcctga
     5101 attaataagg gaagcttcat taaaatttgg agcacaatgt gttgttttat cgatagatgc
     5161 aaagaaaaat gaagagggtt catggagcgt atacgtaaaa ggtggaagag aaaaaactaa
     5221 tctggatgca attgaatggg ctgttaaagg tgtagaactt ggagcaggag aaatcgttgt
     5281 aaatagtatg gatgaagatg gaatgaaaaa tggatatgat atagaattat tatcaaagat
     5341 aacttcttta gtaaatgtac ctgtcatagc atctggaggc gctggaaaaa aggaagattt
     5401 ttatgaggcg gttaataaat ccaatgtaga tggaatttta gcagcatctg tttttcattt
     5461 tggcgagata aaaataaacg atttaaagaa atatttaaaa gacatgggtg tagaagtaag
     5521 attataagtt aaatactaaa aggagattag aaatatggat aataagtgta acaatgtata
     5581 cagtgatgaa gtagagaaat ttataagaag tataaagttt gatgataaag ggttagtccc
     5641 tgttgttgtt caagaggtag ttagcaaaga tgtactgatg ttagcatata tgaataaaga
     5701 tgctataaag aaaaccttaa aagataaagt agcttgctat tttagtagaa gtagacaaga
     5761 actttgggtt aaaggtgaga catctggtaa tactcaaaaa gtagttaaga tgtcttatga
     5821 ttgtgatgta gatactatac tactttttgt tgaacaaact ggtgtagctt gtcatacagg
     5881 caattattct tgtttttaca gagacttgtt tgatgatagt tcaaaaatgg agcttgaagt
     5941 acaaacaaat atattgaaag aattatatga tttaatcaat gaaagaaaaa ataatccagt
     6001 tgaaggttct tatactaatt atctttttga aaaaggaata gataagattc ttaaaaaagt
     6061 aggtgaagag agtagtgagg taattatagc atcaaaaaat accgataaaa gtgaacttat
     6121 ttacgaaatt agcgatttag tatatcatac attggtttta atgatagaaa aaggtgttga
     6181 aattgatgaa ataaaaaaag aattacttaa aagaagaaaa tagaataaga tagattaatg
     6241 ggtaataaga aaatatacca cttttaataa aaagtggtat attttttatt ttatattttg
     6301 a
//
LOCUS       DAJMZY010000157         6247 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.162, whole genome shotgun sequence.
ACCESSION   DAJMZY010000157 DAJMZY010000000
VERSION     DAJMZY010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6247)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6247)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6247
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.162"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            complement(422..2254)
                     /locus_tag="OE968_003533"
     CDS             complement(422..2254)
                     /locus_tag="OE968_003533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCP7220766.1"
                     /translation="MSRMGRGPMGKSMGAGQKANDFKGTMRKLIAYLSKFKISIILVI
                     VFAIGSASFSIVGPKILGKATTKIFEGLVSKVSGGNVGIDFNAIGKILTFLLFLYLIS
                     ALFSFIQGFIMSGISQKVSYNLRKEISAKLDRLPMKYFDTKTHGEILSRITNDIDTLN
                     QSLNQSMTQLITSVTTMIGVLIMMLSISGIMTLVAVLILPISMFVISRIIKKSQKYFR
                     YQQEYLGNVNGQVEETYSGQTIVKAFNREDEVIEEFDKLNDSLYNSAWKSQFLSGIMQ
                     PLMMFIGNLGYVMVSILGGWLAIKKTIEVGDIQSFIQYVRNFTQPMTQIAQVANLLQS
                     TAAASERVFEFLEEEEEVQIVENAVSIDGLEGKIDFENVNFGYNPNKTIINDFSVNVE
                     PGQKVAIVGPTGAGKTTIVKLLMRFYDVNSGSILIDGHNIKDFNRSELREMFGMVLQD
                     TWLFSGSIMENIRYGKLNATDEEVIEAAKSAHVHRFIKTLPDGYKMKLNEEASNVSQG
                     QKQLLTIARAILADPKILILDEATSSVDTRTEVLIQKAMDNLMEGRTSFVIAHRLSTI
                     RDADMILVMNEGDIVEQGNHEELLKKGGFYANLYNSQFEEDEAM"
     gene            complement(2247..4493)
                     /locus_tag="OE968_003534"
     CDS             complement(2247..4493)
                     /locus_tag="OE968_003534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011009877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCP7220767.1"
                     /translation="MFKLIKYLKKSALSIVIIVCLLVIQAVCDLSLPEYTSNIVNVGI
                     QQGGVENSVPSVIRESELNKITLFMDKSSKDKVLDNYTLLNKKDYVKYKDKYPGLKDE
                     SLYELNTKDKDTIDDLNVIFGKAILIVSGLEGDSKEVKAMKAQLMSKLPPQATQSGDV
                     DIFKLLSAMPKEQLDTLTKEMSKGFESMPESMITQSSVSYVRSEYEKIGIDTEKTQNN
                     YILFTGAKMLGIAMISMVATITVGFLAARVAASVGRNLRSGVFRKVMSFSNTEMNEFS
                     TASLITRSTNDIQQIQMLMVMLLRIVFYAPIMAIGGVIKVLNTNTSMAWIIAVAVVAI
                     LSLIVVLFSVVMPKFKLVQKLVDKLNLVSREIITGIPVIRAFSTEKHEEERFDKANKN
                     LTKTNLFVNRVMTCMMPAMMLIMNLITVLIVWRGAYSVDSGAMQVGDMMAFIQYTMQI
                     IMSFLMISMVSIMLPRASVSATRIDEVLVSDISIKDPEKSEAQEFKEDKKGLVEFKNV
                     SFMYPDAEEPILTNISFTAKPGETTAFIGSTGSGKSTLINLIPRFFDVTEGEILLGGV
                     NIKNVSQHDLREKIGYVPQKGVLFSGTIESNLKYGRKDATDEEMRTAAEIAQATEFID
                     SKPEAFKTEISQGGTNVSGGQKQRLSIARAIAKNPEVYIFDDSFSALDLKTDAALRKA
                     LKSKTAESTVLIVAQRISTILNAEQIIVLNEGEIVGIGTHKELLKNCEVYEQIALSQL
                     SKEELANE"
     gene            complement(4561..5022)
                     /locus_tag="OE968_003535"
     CDS             complement(4561..5022)
                     /locus_tag="OE968_003535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HCP7220768.1"
                     /translation="MNSNSEEKLNDVFLQLMRIYFIRTHFYFDKLGLYHGQPQILFSL
                     KMKDGQSQKELADKRKVKASTTTVMIKRMEKAGLVERKQDEKDQRVSRIFLTDKGLEI
                     CNKVEEFNKELEREFFLGFSEEEKIVLRRLLMQVRDNLKAGCHKHEDEKYF"
     gene            complement(5327..5893)
                     /locus_tag="OE968_003536"
     CDS             complement(5327..5893)
                     /locus_tag="OE968_003536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HCP7220769.1"
                     /translation="MRKLEEILEYNKSFVENKEYEQYVTSKHPNKKIVVLSCMDTRLT
                     ELLPKAMNLKNGDVKLIKNAGATIMHPFGSIMRSVLVAIYEFDVDEVMVVGHHGCGMC
                     NVDTDKLLGKILDRGISNDVILTLRSAGIDTKQWLHGFDSAEESVKDSIDLIKGHPLI
                     PDGIIVHGLIISPETGKLDVVVNGYEDK"
BASE COUNT         2024 a         1123 c          651 g         2449 t
ORIGIN      
        1 tacattagtt taattaactt atatgtaatt atcattttat atttaaccct attcttaaat
       61 ttaagtagtt atttgcatga ttaataaaag taataaaaac atatacttca atataatcat
      121 caactattaa aattaaattc tatttataat aaaatttaaa gaataaaatt aaatatacat
      181 tttgataatc acctccaaca ttttccttac tacatattat aataaaataa acactttgta
      241 aagacataaa attatgtggc tatctcaaaa tatagagaat cctctttttc attgttaaaa
      301 tgataaaaat acactttatt tcatacacaa aagagtgcct tatgaattaa aaagttcatt
      361 ttaaggcacc ctcatttatt ttatcttatt aattacatgt ctatgctaag atagtttttt
      421 gttacattgc ttcatcttct tcaaattgag aattgtaaag attggcatag aatccgcctt
      481 tctttagaag ttcctcatga tttccttgtt caactatatc tccttcattc attacaagaa
      541 tcatatcagc atcacgtata gttgataatc tgtgggctat aacaaaactt gttctacctt
      601 ccataagatt atccatagct ttttgaatca atacttctgt tctagtatcg acagaacttg
      661 tagcttcatc taatattaaa attttaggat cagctaaaat agcacgagct atagtcaata
      721 attgtttttg accttgagaa acattacttg cttcttcatt taatttcatc ttatatccat
      781 ctggtaatgt cttaataaat ctatgaacat gtgcagattt agcagcctct ataacttctt
      841 catctgtagc attcaactta ccatatctta tattttccat aattgaacca ctaaataacc
      901 atgtatcttg aagaaccata ccaaacattt ctctaagctc actacgatta aaatctttaa
      961 tattatgacc atcaatcagt attgaaccgc tattaacatc ataaaatctc attaacagtt
     1021 taactattgt agttttacct gctcctgtag gtccaacaat agcaactttt tgaccaggtt
     1081 caacatttac tgagaaatca tttattatag tcttgtttgg gttatatcca aagttgacat
     1141 tttcaaaatc aattttacct tctaaaccat ctattgaaac tgcattttca acaatttgga
     1201 cttcttcttc ctcttctaaa aactcaaata ctctttcaga agctgctgct gttgattgca
     1261 ataaattggc aacctgtgca atctgagtca ttggctgtgt aaagtttctt acatattgta
     1321 taaatgactg tatgtcacca acctcaattg ttttcttaat tgcaagccaa cctcctaaga
     1381 ttgataccat tacatatccc aagtttccaa taaacatcat aagtggttgc attatacctg
     1441 ataaaaattg agatttccac gctgaattat acaggctatc atttagttta tcaaactctt
     1501 caattacttc atcctcacga ttaaatgctt ttactattgt ttggccactg taagtttcct
     1561 caacttgacc atttacattt cctaaatatt cttgttgata tctaaagtat ttttgtgatt
     1621 tctttattat tcttgaaatt acaaacattg atattggtaa tattaaaact gccactaatg
     1681 tcataattcc acttatagat aacatcatta tcaaaacacc tatcatagtt gttactgatg
     1741 ttataagctg tgtcatactt tgatttaaac tttgatttaa agtatctata tcattcgtaa
     1801 ttctcgataa tatttcacca tgcgtcttag tatcaaaata cttcattggc aatctatcca
     1861 attttgctga aatctctttt cttaaattat aggatacttt ttgagaaatt ccactcatta
     1921 taaatccttg tataaaagag aacagtgcac ttatcaaata aaggaaaagt aaaaaggtta
     1981 agatttttcc aattgcatta aaatctatac ctacgtttcc tccagaaact ttactcacta
     2041 gcccttcaaa tatctttgta gttgcctttc ctaaaatttt tggacctact atagaaaacg
     2101 acgcactacc aatagcaaat acaattacta gaattattga tattttaaat ttagataaat
     2161 atgcaattag ttttcgcata gtccctttaa agtcatttgc tttttgtcct gctcccatag
     2221 attttcccat aggacctctt cccattctac tcattagcta gctcctcctt tgaaagttgt
     2281 gataaagcta tttgctcata aacttcgcaa ttttttagaa gctctttatg tgttcctatt
     2341 ccaactattt cgccctcatt taaaacaatt atctgttctg catttaagat agtactaatt
     2401 ctttgtgcaa ctattagaac tgtactttca gcagtttttg attttaaagc cttacgaaga
     2461 gctgcatcag tttttaagtc aagtgctgaa aaactatcat caaatatata aacttctgga
     2521 ttttttgcta ttgctcttgc aatagaaagt ctttgttttt gacctccaga tacatttgtt
     2581 ccaccttgag aaatttcagt tttaaaagct tccggtttag aatctataaa ttctgtagct
     2641 tgagctattt cagctgctgt tctcatttct tcatctgttg cgtcttttct accatatttt
     2701 aagttggatt ctatagtacc agaaaacaat actccctttt gaggtacata tccaattttt
     2761 tcccttaaat catgttgaga aacatttttt atattaactc caccaagtaa tatttctcct
     2821 tcagtaacat caaagaaacg aggaattaaa tttataagag ttgacttacc actaccagta
     2881 cttcctataa aggcagttgt ttctcctggc tttgctgtaa aagatatatt tgttaatata
     2941 ggttcttctg cgtctggata catgaacgaa acatttttaa attcaacaag acccttttta
     3001 tcttccttaa actcttgtgc ctctgatttt tctgggtctt ttatgcttat atctgacact
     3061 aatacttcat ctatacgtgt agctgaaacg gatgctcttg gaagcataat agataccatt
     3121 gatatcatta agaatgacat tattatttgc attgtatatt gtataaatgc catcatatct
     3181 ccaacttgca ttgctccaga atcaacactg tatgcacctc tccaaactat aagaactgtg
     3241 ataaggttca ttataagcat catagcaggc atcatacatg tcataactct atttacaaaa
     3301 agatttgttt tagttaaatt tttatttgct ttatcaaatc tttcttcttc atgtttttca
     3361 gtactaaaag ctctgataac tggaatacca gtaattattt cacggcttac taagtttaac
     3421 ttatcaacaa gcttttgaac cagtttaaac ttaggcataa ccactgagaa taacactaca
     3481 attaatgata agatagcaac tactgctact gctataatcc aggccattga agtatttgtg
     3541 tttaaaacct ttatcactcc acctatagcc attataggtg catagaatac tattctaagc
     3601 aacataacca tcaacatttg tatctgttga atatcatttg tactacgagt aattaatgaa
     3661 gctgtagaaa attcattcat ttcagtattt gaaaatgaca taacttttct aaatactcca
     3721 cttcttaaat ttctacctac acttgcggct actcttgctg ctaaaaatcc tactgttatt
     3781 gtagctacca tactaatcat tgctatacca agcattttag caccagtaaa taatatataa
     3841 ttattttgag ttttttctgt atcaatacct attttctcat attctgacct tacatatgaa
     3901 acagagcttt gtgttatcat actctctggc atactttcaa agcctttgct catctcttta
     3961 gtcaatgtat ctaactgttc ctttggcatt gctgataaca atttaaatat atcaacatct
     4021 ccactttgag tagcttgtgg tggaagttta ctcattaact gagctttcat agcttttacc
     4081 tctttactat cgccctcaag ccctgatact attaaaatag ctttaccaaa aataacattt
     4141 aaatcatcta tagtgtcttt gtctttagta tttaactcat aaagagattc atcttttaga
     4201 cctgggtact tatctttata cttaacataa tcctttttat tcagcaaagt ataattatct
     4261 agtactttat ccttactact tttatccata aataaagtaa ttttatttaa ttcactctct
     4321 ctaatcacag atggaacaga gttttctact ccaccttgtt gtatacctac atttactata
     4381 ttggatgtgt attctggtaa agaaaggtca cataccgctt gaattaccaa tagacagact
     4441 attattacta ttgataatgc cgatttcttt aaatatttaa ttaatttaaa catacatttc
     4501 ttcccttctg taatattaat tagtctaata acattaaatt gaaaaacatt attttaaact
     4561 ttaaaaatat ttttcatctt catgcttatg acatcctgct tttaaattat ctcgtacttg
     4621 cattagaagt cttctaagta ctattttttc ttcttcacta aatcctaaaa aaaactctct
     4681 ttccaattcc ttgttaaatt cttcaacttt attacatatt tctaaacctt tgtctgtcaa
     4741 aaaaatccta gatactcttt ggtccttttc atcttgtttt ctttccacaa gtccagcttt
     4801 ttccatcctc tttatcataa ctgtagttgt agatgctttt actttccttt tatctgctaa
     4861 ttctttttga ctttgcccat ctttcatctt taaagaaaaa agtatttggg gttgaccatg
     4921 atataagcct aatttatcaa aataaaaatg agttcttata aaatatattc gcattaattg
     4981 caagaaaaca tcatttaatt tttcttcaga attgctattc atacttgccc tccttatttt
     5041 ttatattact tagtcggcta agcattattt tactatactg catgcatttt ttcaatatat
     5101 ttataaaaaa ttcatataaa tttcatttat taaatatttt tatatcatat agttataatt
     5161 ttaataaata atagtaagat ttttaattag tcagctactt atatttttta ttgtaaagct
     5221 taaaataaac cttttcatat attttcaaat aaaaaagttg tcccaaaata aattttgaaa
     5281 caacatctta ttcaacagta tcttgattat ataacattat gatactctac ttatcttcat
     5341 atccatttac aacaacatct aacttcccag tttcaggtga tataattaga ccatgtacaa
     5401 taataccatc tggaattaaa ggatgccctt ttattaaatc aatactatct tttacagatt
     5461 cttctgcaga atcgaatcca tgtaaccatt gttttgtatc aattccagca ctacgaagtg
     5521 taagtattac atcattagat attcctctat ctaaaatttt accaagtaac ttatccgtat
     5581 caacattaca cataccacat ccatgatgcc ctacaaccat aacctcatct acatcaaatt
     5641 cgtaaattgc aactaaaaca cttctcataa tacttccaaa aggatgcatt atagtagctc
     5701 ctgcattttt tattagtttc acatctccat ttttcaaatt catagcctta ggcaaaagct
     5761 cagttaatct tgtatccata caagataaga ctactatttt tttatttgga tgttttgatg
     5821 tcacatattg ttcatattct ttgttctcta caaatgattt attatattct aatatctctt
     5881 caagttttct catatgtaat atcaccctct ttaaaaattt ttttattatt atatcactat
     5941 taaagtacaa tatatacaca tataatttaa tttatattta ttaaattatt ttataagatt
     6001 attactctac tataaatctt gtatataact tgtatttata agtatttgta tatttatttt
     6061 ttataatcta aactaatatt atatattttc attatttttt taattataat ttttttaaaa
     6121 ttttattcta aatgccttac ttataattaa ttttttattt cacctatata taattagatt
     6181 taaaaatgtt taccttacca atataatgat taaactcaaa agtcttattg aaaaattttc
     6241 tatttac
//
LOCUS       DAJMZY010000158         6142 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.163, whole genome shotgun sequence.
ACCESSION   DAJMZY010000158 DAJMZY010000000
VERSION     DAJMZY010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6142)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6142)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6142
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.163"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            complement(472..2607)
                     /gene="rnr"
                     /locus_tag="OE968_003537"
     CDS             complement(472..2607)
                     /gene="rnr"
                     /locus_tag="OE968_003537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HCP7220770.1"
                     /translation="MIPGLKESLLGLINESAYNPLKKEELAEIFDIHSSEMPMFYNFL
                     NELEEDGYICFTKKGKIVSPNQMGYFVGKFVSHKKGFGFVESDVEYTQDLFISSDNIN
                     GAMHNDRVMAEIVVPATEEKRAEGRIVKVIKREITRIVGTFQSSKTFGFVTPDNKKFT
                     KDIYIPKKHFSGAVDNDKVVCEITVWPQEDRKPEGKIIEILGQKGERGVEIDSIIREH
                     GLPEEFPKKVLQEAEAVAVEIPQEEIKRRRDLRDLNIFTIDGDDAKDLDDAISIEVLP
                     NGNFKLGVHIADVTHYVREKNKLDKEALKRATSVYLVDKVIPMLPKTLSNGVCSLNPF
                     EDKLTLSIFMEIDHKGNVVKHEICESVINSKARMTYTEVSDILEKDDEKLKKTFEHVV
                     EDFKNAEILARILMSRREKRGAIDFNFPEAKIILNGKGEVVDIKPYERRISNKIIEEF
                     MLISNETIAEHFYWMGIPFVYRIHETPSLEKMEELSKFISTFGYIIKGDKEEVHPKAL
                     QGIIEKIKGKKEEGAISTIMLRSLKQAKYSPECSGHFGLAAKFYCHFTSPIRRYPDLQ
                     IHRIIKESLNNKISGKRQEQLTTIVDYASVQSSEKERKAELAERDVHDFYKALYMKDK
                     VGQEFEGVVSSVTSFGIFVELDNTIEGLIRLANMNDDYYIYDESSYSVLGERTKKSYK
                     IGDLVKIKVESVNVDFKEIDFEIVEKIEE"
     gene            3200..3814
                     /locus_tag="OE968_003538"
     CDS             3200..3814
                     /locus_tag="OE968_003538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HCP7220771.1"
                     /translation="MEEVIAKIITIENGFKEIENIAKKIVKNNDSKKCYYLSIYLYRS
                     EYYQVRELAVFILGFISVTISEALLFLKDNVSKDENWRVQEILAKSFDYYCSEVGYEK
                     ALPVIKEWLNSDSPNIKRAVTEGLRIWTNRDYFKSNPDVAISLLSSLKEDDSEYLRKS
                     VGNALRDISKKYPDLVKKELDSWDISNKKVEFVYKLASKCILAK"
     gene            3832..4194
                     /locus_tag="OE968_003539"
     CDS             3832..4194
                     /locus_tag="OE968_003539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCP7220772.1"
                     /translation="MKLRDEYTCPLELTHDMIKGKWKSIILWRLRIGPTSLSKLEKEI
                     NGINQKMLLEQLKELIEFGLVDKKTYEGYPLKVEYSLTPIRGKQILDALAIMQDIGIS
                     FMLDNGMEDILKEKGVLK"
     gene            4300..4797
                     /locus_tag="OE968_003540"
     CDS             4300..4797
                     /locus_tag="OE968_003540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbhB/YbcL family Raf kinase inhibitor-like
                     protein"
                     /protein_id="HCP7220773.1"
                     /translation="MKVTSTGIVNGVIEDKYGKRGTQFNEGGMPTYSLPLKFEDAPKN
                     TVSFAVFLEDKDSVPVCGFAWIHWLAVNITKDELNENESVTATDFVQGTTSWHGKLGG
                     LDRLEASVYGGMAPPDRPHVYEIHVFALDTILDLEKGFYMNEFFKAIEGHVLDTFTLK
                     GSYSN"
     gene            5601..>6142
                     /locus_tag="OE968_003541"
     CDS             5601..>6142
                     /locus_tag="OE968_003541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCP7220774.1"
                     /translation="MIAVKKAYKFRIYPNKKQQELINKTFGCCRFVYNKYLAKRIDVY
                     KNDKETFTYKQCSSDLTNLKKELNWLKEPDKFSLQNALKDLDNAYKKFFKEKAGFPKF
                     KSKKINRFSYKTNFTNGNIMYCGQHIKLPKLGMVKVRDKQVPKGRILNATISKEPSGR
                     YYVSLCCTDVDIEAFENTNN"
BASE COUNT         2113 a          900 c          797 g         2332 t
ORIGIN      
        1 tagccacttc tattaagcat ttcttaatta cttatttttc aattagccac ttctattaag
       61 catttctcaa ttacttattt ttcaattagc cacttctatt aagcatttct taattactta
      121 tttttcaatt agccacttct attaagcatt tcttaattac ttatttttca attagccact
      181 tctattaaac atttcttaat tatttatttt tcagttggct ttttctatta aatgtttctt
      241 aattacttat ctttcagtta gctctttcta ttaaacattt ctcaattact tatttttcaa
      301 ttagctactt tcattaaata tttcttaatt atttatcttt cagttaacta tttccattag
      361 atatttctca attacctatt tttatcattt attttataga gtattgtgca ctatatattt
      421 atacatatca taaatactac aacttgttat ctcttatttt agctgtttta tctactcctc
      481 tattttttca actatctcaa agtcaatttc tttaaaatct acattaacac tttcaacctt
      541 tatcttaaca aggtcaccta tcttatatga cttcttagtt ctttctccta aaacactata
      601 agaactctca tcataaatat agtaatcatc attcatattt gcaagtctta tcaacccttc
      661 tatggtatta tctaactcaa caaatattcc aaatgaagtt acgctagata caacaccctc
      721 aaattcttga ccaactttat ccttcatata aagagcctta tagaaatcat gtacatctct
      781 ttcagctaac tctgcctttc tttctttctc ggatgattga acagatgcat aatccactat
      841 agtagtaagc tgttcttgtc tttttccact tattttatta tttaaagatt cttttattat
      901 tctatgaatt tgaaggtcag gatatcttct tattggtgaa gtaaagtgac agtagaattt
      961 agctgctaat ccaaaatgtc cactacattc tggtgagtac ttagcttgtt ttaaagaacg
     1021 aagcattata gtactgatag ctccttcttc ttttttgccc tttattttct ctattatacc
     1081 ttgtaatgct tttggatgta cttcctcttt atcacctttt attatatatc caaatgtaga
     1141 tataaactta ctcaattctt ccattttttc caaagatggt gtctcatgta ttctatacac
     1201 aaacggtatt cccatccagt aaaaatgttc ggcaattgtc tcattactta taagcataaa
     1261 ttcttctatt atcttattag atattcttct ttcatatggc tttatatcta caacttcgcc
     1321 ttttccattt agaattatct ttgcctctgg gaaattgaag tctatagctc ctcttttttc
     1381 ccttcttgac ataagaatcc tagctaaaat ttcagcattt ttaaaatctt caacaacatg
     1441 ttcaaaagtc tttttaagtt tttcatcatc cttttctaat atatcagata cttctgtata
     1501 agtcattcta gcttttgaat ttattacaga ttcacatatt tcatgtttaa ccacatttcc
     1561 tttatggtct atttccataa atatagaaag agttagctta tcttcaaatg gatttaagct
     1621 acatactcca tttgaaagag tttttggcaa cattggaatt actttatcta ctaaataaac
     1681 tgatgtagct ctttttaagg cttccttgtc aagtttattt ttctctctta cataatgtgt
     1741 aacatcagct atgtgaactc ctagtttgaa gtttccatta ggtaatactt ctattgatat
     1801 ggcatcatct aagtcttttg cgtcatctcc atctatagta aatatgttta aatctcttaa
     1861 atctcttctt ctttttatct cttcttgagg aatctcaaca gctacagctt ctgcttcttg
     1921 caatactttc tttggaaatt cttctggaag accatgttct cttattatag aatctatttc
     1981 tacgcctctt tcaccttttt gacctagtat ctctataatt ttgccttctg gttttctatc
     2041 ctcttgtggc catactgtaa tttcacatac taccttatca ttatctactg ctccactaaa
     2101 atgtttttta ggtatatata tatctttagt aaatttcttg ttgtctggtg ttacaaatcc
     2161 aaaagtttta cttgattgga aggtacctac tattctagtt atttctctct ttattacttt
     2221 tactattctt ccttctgctc tcttttcttc agttgcaggt actactattt ctgccataac
     2281 tctatcatta tgcatagcac catttatatt gtcacttgag ataaataaat cctgtgtata
     2341 ttcaacatca gattctacaa atccaaaacc ctttttgtgt gatacaaatt ttccaacaaa
     2401 gtatcccatt tgattgggag atactatttt tcctttttta gtaaagcaga tataaccatc
     2461 ttcttctaat tcatttaaaa aattataaaa cattggcatt tctgatgaat gtatatcaaa
     2521 tatttctgct aattcttctt tttttagagg attatatgca ctttcattta ttaatcctag
     2581 caaactttct ttaagtcctg gtatcatttt tccctcctgt tttacttttc attatattat
     2641 tatttatatt gtcttttata tttcttcaga caaaacattt tttacttatc acataatttt
     2701 ctatattttc ttattattat aagttaaaat tacttattta tatttttgat ttaatgtaat
     2761 ctttgtcata ctaacttcaa acaaattatg atgttttata aattatttgt aaatatcatt
     2821 ataattactt aagttattct ttatcataat tgcttaaatt actctttatc acctaattat
     2881 acaccatcaa ataggattgg taaaatattc atctcatata agtattacta tataataatt
     2941 tattctatta gtatactcaa atcatgtaaa atttatataa ctcaattaat tttttaaata
     3001 caactttata atataaaact tataataaaa gtaaatttat atgttaaatg aggttgattt
     3061 tttattattt tttatttatg ctagtactaa agacttgcaa acgttttttg acaagtcttt
     3121 attttgtcta aattaaacaa acttttttac aaataaatac ataaaattta aactaatcta
     3181 tttattggag gagataaaat tggaagaagt aattgcaaaa attattacta tagaaaatgg
     3241 attcaaagaa attgaaaaca ttgctaaaaa aattgtaaaa aataatgact caaaaaagtg
     3301 ttattatcta tcaatctact tatataggtc agaatattat caagtaagag aattggctgt
     3361 gtttatactt ggttttatat cagtaactat ttctgaagct ttgttatttt taaaagataa
     3421 tgtgagtaaa gatgaaaact ggagagtaca agaaatacta gctaaatcat ttgattatta
     3481 ttgcagtgaa gtaggatatg aaaaggcact tcctgttata aaagaatggc ttaattctga
     3541 tagtccaaac ataaaaaggg ctgtgacaga aggtcttcga atttggacta atagagacta
     3601 ttttaaatct aatcctgacg ttgctatatc actactttct agtttaaaag aagatgatag
     3661 cgaatacttg agaaagtctg taggtaatgc tcttagagat ataagtaaaa aatatccaga
     3721 tttagtaaaa aaagaattag attcatggga tatatcaaat aaaaaagttg agtttgtata
     3781 taagcttgct tcaaaatgta tcttggcaaa gtaaaatgga ggtgaactta tttgaaactt
     3841 cgtgatgagt atacttgccc attagaacta acacatgata tgataaaagg caaatggaaa
     3901 tctattatat tatggagatt acgcatagga ccaacttcct tatcaaaact tgaaaaggaa
     3961 atcaatggta ttaatcaaaa gatgttactt gaacaactta aagaattaat tgaatttggt
     4021 cttgtagata aaaagacata tgaaggttac ccacttaaag tcgaatactc acttacacct
     4081 attcgaggga aacaaatatt ggatgctttg gctataatgc aagatatagg aattagcttt
     4141 atgttggata atggtatgga agatattctt aaggaaaaag gtgttttaaa ataaatagat
     4201 acccacaaaa aagtaagtaa tttaccatta ttttcaactg gtatataatt aaattataga
     4261 tatattctat taatttatta taataggagg taaattatta tgaaagtaac tagtacaggt
     4321 atagtaaatg gtgttataga agataaatat ggtaaaagag gaactcagtt caatgaaggt
     4381 ggtatgccta catattcact acctctaaag tttgaagatg ctccaaagaa tacagtatcc
     4441 tttgctgtat ttttagaaga taaagactct gttcctgtat gtgggtttgc atggatacat
     4501 tggttagctg taaatataac aaaagatgag ttaaatgaaa atgaaagtgt aacagctact
     4561 gattttgtac aagggactac tagttggcat ggtaaactag gaggtcttga cagattagag
     4621 gccagtgtat atggtggaat ggctcctcca gacagacctc atgtctatga aatacatgta
     4681 tttgcacttg atactatcct tgaccttgaa aaaggattct atatgaatga atttttcaaa
     4741 gctattgaag ggcatgtttt agatacattt acactaaaag gaagttattc taattaatta
     4801 ggttgactat agctaatcat taattaaatg atacatttaa ttgatgatta gcttaattgt
     4861 tattagaata ttttctgcac tttatcttaa tatatatttt agttgactgg tattttaatt
     4921 tctattagat tattatcaat ttatataaat tgattaaaaa atagctacgc acactcgtga
     4981 ctttagtcat gagttagtag ctaaaatagt cagcatatag ggaaacttat atgtagagat
     5041 aggatagaac ctatccaata ctacttgaat tgctaaaaac ccctaaagct aaccaaacta
     5101 aaacataagg atgaaataaa cctaagtgtg aaagttacga aagtagaaaa aattggttag
     5161 atggtataag gttaaaccct aagtacttta aaatgggcaa tcagcaggta aactccaaat
     5221 aggagaaact tcaacgacta ttcctcttga gggaagtaca ctacaagtta tcggtagtgg
     5281 aagtgggtag accttagcag ataatgccga aggataagat atagtctgtg cttatgtgaa
     5341 agtgtaagaa gttcataaga gaactgcata ggtagtagcg aacttatgtg aacgacaacc
     5401 tcaaaaatga taaaagttaa gacttacggt tcttatatat gttatttaaa attaaatata
     5461 aaaccttcta aataattgtt ttaaataatt acatttgtta acattattat aggtgattaa
     5521 taaattgttc accacagcat tatataatat attaaatatt aaaatcatta aaaagtgtat
     5581 caaaaaacaa ttaaagtgag gtgatagcag tgaaaaaagc ttataagttt agaatatatc
     5641 ctaataaaaa acagcaagag ttaattaaca aaacttttgg atgttgtagg tttgtatata
     5701 ataaatatct tgctaaaaga atagatgttt ataaaaacga taaagaaact tttacttata
     5761 aacagtgtag ttctgattta accaatttaa aaaaagaatt aaattggctt aaagaacctg
     5821 ataaattttc actacaaaac gccttaaaag atttagataa tgcatataaa aaattcttta
     5881 aagaaaaggc aggatttcct aaatttaaat caaagaaaat taatagattt tcatataaaa
     5941 ctaactttac aaatggaaac attatgtatt gtggtcaaca tataaaacta cctaaacttg
     6001 gtatggttaa ggtaagggat aaacaagtac ctaaagggag aatacttaat gctactatat
     6061 ctaaagaacc aagtggtaga tattatgtat cattatgctg tactgatgta gatattgaag
     6121 catttgaaaa tactaataat ca
//
LOCUS       DAJMZY010000159         6122 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.164, whole genome shotgun sequence.
ACCESSION   DAJMZY010000159 DAJMZY010000000
VERSION     DAJMZY010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6122)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6122)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6122
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.164"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            17..1369
                     /locus_tag="OE968_003542"
     CDS             17..1369
                     /locus_tag="OE968_003542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HCP7220775.1"
                     /translation="MTVTIAGWIILSFLFLGIIIYILYSKANSQKTIEKVAYTDFVTG
                     YSNWRKFELDVTNLLKKTSQNNKYAMVIFDIDKFKAINDIYGHKKGNLILKDIADTLN
                     ELTDINETFARVSADNFNILLTYNKKEDIINIIKKIMANNELVNLSFGIYEIKDKDLS
                     VSVYSDRASLAKSSIKNNSDVNFAFFNDKLREKLLFEDKIEKEMEYALESGQFVMYLQ
                     PKYNIKLDKFCGSEALVRWQYTEKEVIYPGDFIPIFEKNGFIRKIDMYILEQACKEIR
                     SLFDKGISPLPISVNFSRVDFFKKDFIENIVNICDRYKIPYSLIEIEITESSMFGDTD
                     TLFNVSRNLQDIGFIVAMDDFGSGYSSVNMLKNIPLNVIKLDRGFFVYDKDVDKSQIV
                     IKSIVSLIKQLGIRVVAEGIETRSQIEMLKKANCDIVQGYYFSKPLPIKEFEKLVYKI
                     "
     gene            1402..4839
                     /locus_tag="OE968_003543"
     CDS             1402..4839
                     /locus_tag="OE968_003543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing protein"
                     /protein_id="HCP7220776.1"
                     /translation="MIRAKSLKNVLSIVLIFLFTIISFSDFAFKTNVQEEENSKINLR
                     EISLQSSNAIKIKLDSSLSFIKSVANMVSYFNTIDNSKIVPLLANISKESDFQRISIV
                     SPDGISHTSDGKIINVSKYQYFKKAIKGESNISEVVKSPIDGKDTFVIATPVFNKNNK
                     IIGVLYGSYYNDKLAEFIDITSFNSEGYIDIFESSGQFVLKSSHTNKLIKSSSNIYDI
                     FKKASFDDGYSYKKIYEDTKNNKSGFTSYEYKGENRYATYTPIGVNDWYVISVIPQYT
                     VRRNIDKINQLAFSLIFKVFLLFIMLITYIIYKNNKSQKDILKANKEISSITNSIPGG
                     VQKCTLGETCNINFLSDGFIELFGYTREEIKTLFNNDFYSLIHKDDVERIKKEIFKQL
                     YKNKTVELEYRIITKNGNTVWVLDKGELITEPDGKEYFCCVTVDITRTKQLEQEMEQK
                     NLELEMISENVLGGIIITEFNDDFTIKYANSGYLSMIGYTREQLENELKYKACNLVFY
                     EDRKKALESIQHQLNTKGIAVYQHRIRRRDGNIIWVSIKGRLIVDDDGIEKGIWILND
                     ITDLKNAEQKLKINEERFRIALKQTSNTIFEYDIKTKSLLNTSKELDKYNIYKITKNV
                     PYSLVELGVIHKDFSDDFINMYENVINGAKKASCVVKMKLPDENYIWNKVTLTTIFDE
                     DGNPVRAIGIQEDISKQKEAEIRYNQEGKYHSAILSEAMITYEINVSKDTFIKGNESW
                     QKPFGIKPDNNYSQMVKTIANSIVHKDNKETFLNTFLCENLLDAYKNNVTEIKLEYRR
                     MNQENKMIWVICTMHLIKDSITNDIKALAYVKDIDKQKNEEIRLKLKAERDTLTGLYN
                     KGTTEKLINDFLNSEEASLGMHAFLIVDIDNFKSVNDNLGHVFGDKVLFEVSKNLKPI
                     FRKDDIVGRIGGDEFIVFLKNIQSFENIKKKAEKICDIFRNSYTENKKTYKISGTVGI
                     SFVPEHGTVFEELYKKADIALYYAKSKGKDKYALYNDCIYQNELENNISDNNIKLADK
                     CEKSKPVLKEILDSIDNYIYIVNPNTYELLFVNNKVSRLDLEIKLGETCYKSLLKSDR
                     PCNNCPLNGLEENKHSKFKIETNTFGKNISIASWINCIDGEYNCLIECIDSSLYKNK"
     gene            4857..5603
                     /locus_tag="OE968_003544"
     CDS             4857..5603
                     /locus_tag="OE968_003544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HCP7220777.1"
                     /translation="MLNSITLILGIIFTIYYFYLKIVFGGISFSEIFLVVGIVLIIYQ
                     IFKKKIKEKKVFYRVLKIIISIFLIVFVVTESLIIFYPKNSLESKSDYLLILGASVKK
                     TTPSTTLKGRLDTALKYLKINDNCYVVVSGGKGSGEKITEAKAMKDYLIKNGIDKNRI
                     IEEDKSTNTYENFKYSKLKIEEHSQRKLSDLKVKIVTTDFHVLRSKILAYRNGYKNTS
                     FYASKSKLSFVPTYYTREFFALWKTIIFDR"
     gene            complement(5552..5860)
                     /locus_tag="OE968_003545"
     CDS             complement(5552..5860)
                     /locus_tag="OE968_003545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HCP7220778.1"
                     /translation="MNFLKENSTFYFATVEDNKPRVRPFGFIMDYEGKLYFGIEKYKT
                     SYKQLLVNPNIEISTTSKVGKWIRIKGIEKTRYEFISSLFIYYLSKMIVFHNAKNSLV
                     "
BASE COUNT         2557 a          606 c          925 g         2034 t
ORIGIN      
        1 tgaaacaaat gacataataa cagttacaat tgctggatgg attatacttt catttttatt
       61 tttaggtatt ataatttaca tattatattc aaaagcaaat agtcaaaaaa ctatagaaaa
      121 agtagcatat acggattttg taacaggtta ttccaactgg agaaagtttg aattagatgt
      181 tacaaattta ttaaagaaaa catcacaaaa taataaatat gcaatggtca tattcgatat
      241 tgataaattt aaagcaatta atgatatata tggccataaa aagggaaatt taatattaaa
      301 agatattgca gatactttaa atgaattgac tgatatcaat gaaacttttg ctcgtgtaag
      361 tgctgataat ttcaatatat tattaacata taacaaaaaa gaggatataa taaatattat
      421 caaaaagatt atggcaaata atgaacttgt aaacttatct tttggaattt atgaaatcaa
      481 agataaggat ttatctgtaa gtgtatatag tgatagagct tcacttgcaa aatcatcaat
      541 aaaaaataat agtgatgtaa attttgcatt ttttaatgac aaattaagag agaaattatt
      601 atttgaagat aagatagaaa aagaaatgga atatgctctt gaaagtgggc aattcgtaat
      661 gtatttacaa ccaaaataca atattaaatt agataaattt tgtggaagtg aagccctagt
      721 cagatggcaa tatacagaaa aagaggtcat atatccaggt gattttattc ctatatttga
      781 aaaaaatgga tttattagaa agattgatat gtacatatta gaacaagctt gtaaagaaat
      841 ccggtcttta tttgataaag gaatttcacc tttacctata tctgtaaact tctcaagagt
      901 tgattttttt aaaaaagatt ttattgaaaa catagtaaat atatgtgata gatataaaat
      961 accatatagt ttaatagaaa ttgaaattac tgaatctagt atgtttggag atactgatac
     1021 tctatttaat gttagtagaa acctacagga tattggcttt atagttgcaa tggatgattt
     1081 tggctctgga tattcttctg taaatatgct taaaaatata ccattaaatg taataaaatt
     1141 agatagagga ttttttgttt atgataaaga tgttgataag agtcaaattg ttataaaaag
     1201 catagtttct ctcattaagc aattaggaat aagggttgtt gctgaaggaa ttgaaacaag
     1261 aagtcaaata gaaatgttaa aaaaagcaaa ttgtgatatt gttcaaggat attatttttc
     1321 aaaaccatta ccaattaaag aatttgaaaa attagtctat aaaatatagt cagcgagtct
     1381 taaatgggag gtggtgatta agtgataaga gcaaaatcgt taaaaaatgt actgagtatt
     1441 gttttaatat ttttatttac aataatttct ttttctgatt ttgcatttaa aactaatgtc
     1501 caggaagaag aaaatagtaa aattaattta agagaaatat ccctacaaag ttccaatgct
     1561 ataaaaataa aattagatag ttctctatcc tttattaaaa gtgtggcaaa tatggtttct
     1621 tattttaata ctatagataa ctcaaaaata gttccattat tagctaatat atcaaaagaa
     1681 tctgactttc aaagaatctc tattgtatct cctgatggaa taagtcatac cagtgatggc
     1741 aaaattatca atgtgtcaaa gtatcagtat tttaagaaag ctattaaagg agaaagtaat
     1801 atatctgaag ttgtgaaatc tccaattgat ggaaaagata cttttgttat agctactcct
     1861 gtatttaata agaataacaa aataattggt gttttatacg gttcttacta caatgataaa
     1921 ttagctgaat ttatagatat aacaagtttt aatagtgaag ggtacataga tatatttgaa
     1981 tctagtggtc aatttgtttt aaaatcttca catacaaaca aactgattaa gtcaagtagt
     2041 aacatatatg atatatttaa aaaagcttct tttgatgatg gttatagcta taaaaaaata
     2101 tatgaagata caaaaaataa caagagtggc tttacctcat atgaatacaa aggagaaaat
     2161 cgttatgcta cttatacacc cattggtgta aatgactggt atgtaatttc tgtgatacca
     2221 caatatactg taagaagaaa cattgataaa ataaatcaat tagcattttc tcttattttc
     2281 aaggtattct tattgtttat tatgcttata acatatatta tttataaaaa caataaatct
     2341 cagaaagata tactaaaagc taacaaagaa atctcatcta ttacaaatag cattcctgga
     2401 ggagtacaaa agtgtaccct gggtgaaaca tgcaatatta attttttaag tgatggattt
     2461 atagagttgt ttggttatac aagagaagaa ataaaaacat tgtttaataa tgatttttat
     2521 agtttaatac ataaagatga tgttgaaaga ataaaaaaag aaatttttaa acaactttac
     2581 aaaaataaaa ctgttgaatt agaatatagg attataacaa aaaatggtaa tacagtatgg
     2641 gttttagata aaggggagct tataacagaa cctgatggaa aagaatattt ttgttgtgta
     2701 actgtagata ttactagaac aaaacaatta gaacaagaga tggaacaaaa aaatctagaa
     2761 cttgaaatga tatcagaaaa tgttttaggt ggtataatta taacagaatt taatgatgat
     2821 tttactataa aatacgctaa ctctggttat ctttcaatga ttggatatac acgtgaacaa
     2881 ttagaaaatg aacttaaata caaagcttgt aatcttgttt tttatgaaga tagaaagaag
     2941 gctcttgaaa gtatacaaca tcaattaaac acaaaaggaa tagctgtata tcaacataga
     3001 ataagaagaa gagatggtaa tattatttgg gtttctataa aaggaaggct tattgttgat
     3061 gatgatggta ttgaaaaagg tatttggatt ctaaatgata taacagattt aaaaaatgca
     3121 gaacaaaaac ttaaaataaa tgaagaaaga tttagaattg cattaaagca aacatcaaac
     3181 actatatttg agtatgatat aaaaacaaag tcacttttaa atactagtaa agagcttgat
     3241 aaatataata tttataaaat tactaaaaat gttccatatt ctctagtaga attaggagtt
     3301 attcataaag attttagtga tgattttata aatatgtatg aaaatgtaat aaatggagca
     3361 aaaaaagcaa gttgtgtagt taagatgaaa cttccagatg aaaattatat atggaataaa
     3421 gttaccttga ctacgatttt tgatgaagat ggtaatcctg taagagcaat tggtatacag
     3481 gaagatataa gcaaacaaaa ggaagcagag ataagataca atcaagaagg taagtatcat
     3541 tcagctatat tgtcggaagc aatgataact tatgaaataa atgtatcaaa ggatactttt
     3601 atcaaaggaa atgaaagttg gcaaaaacca tttggaatta agcctgacaa taactattct
     3661 caaatggtaa aaactatagc aaatagtatt gtacataaag acaataaaga aacattttta
     3721 aatacatttt tatgtgaaaa cttattggat gcatataaaa ataatgtgac tgaaataaaa
     3781 ttagaatatc gaagaatgaa tcaagaaaat aaaatgattt gggtcatttg tacaatgcac
     3841 ttaataaaag attctattac gaacgatata aaagcacttg cttatgttaa agatattgac
     3901 aagcaaaaaa atgaagaaat tagattaaaa ttaaaagctg aaagagatac tcttacagga
     3961 ttatataata aaggtactac agaaaaattg attaatgatt tcttgaactc tgaggaagca
     4021 agcttaggaa tgcatgcatt tttaattgtt gatatagata attttaaatc tgtgaatgat
     4081 aatttaggac atgtatttgg agataaagta ttatttgaag tttctaaaaa cctaaaacct
     4141 atatttagaa aagatgatat agtaggtaga attggtggag atgaatttat agtattctta
     4201 aaaaatattc agtcttttga gaatatcaaa aagaaagcag aaaaaatatg cgatatattt
     4261 agaaattctt atacagaaaa taaaaagaca tataaaatat ctggaacagt tggaatttca
     4321 tttgtaccag aacatggaac tgtatttgaa gaactttata aaaaagcaga catagcactt
     4381 tattatgcaa agagcaaagg aaaagataag tatgcacttt ataatgattg tatctaccaa
     4441 aatgaacttg aaaataatat aagtgataat aatataaagt tagcagataa atgtgagaaa
     4501 tccaaaccag tacttaaaga aattcttgat tctattgata attatatcta tatagtgaat
     4561 ccaaatactt atgaacttct ttttgtcaat aataaggtgt ctcgtttgga tttagagata
     4621 aaattaggag aaacctgtta taaatcacta ttaaaatctg atagaccatg taataattgc
     4681 cctcttaacg gattagaaga aaataagcat tcaaaattca aaatagagac aaatacattt
     4741 ggtaaaaata tcagtatagc aagttggatt aattgcatag atggagaata caactgtctt
     4801 atagagtgta tagattcttc tttatacaaa aataaataaa aaaggactat gaagatatgt
     4861 taaatagtat aactttgata cttggtataa tatttacaat ttactatttt tatctcaaaa
     4921 tagtttttgg aggaatttca tttagtgaga ttttcttagt tgtaggaatt gtactaatta
     4981 tctatcaaat atttaagaaa aaaattaaag aaaagaaggt tttttatagg gtgttaaaaa
     5041 taataatcag cattttttta atagtatttg tagttactga gagtctaatt attttttatc
     5101 ccaaaaatag tttagaatca aaaagtgatt atctcttaat tttaggagct tctgtaaaaa
     5161 agactacacc aagtacaacc ctgaagggta ggttagacac tgcattgaaa tacctaaaaa
     5221 ttaatgataa ttgttatgtg gtagtatctg gtggtaaagg aagtggagaa aaaataactg
     5281 aggcaaaagc tatgaaagat tatcttataa aaaatggtat agataaaaat aggataatag
     5341 aagaggataa atccacgaat acttatgaga attttaaata ttcaaaattg aagatagaag
     5401 aacatagtca aagaaaacta agcgatttaa aagtaaaaat agtaacaaca gattttcatg
     5461 ttctcagaag taaaatatta gcatatagaa atggatataa aaatacgtct ttttatgcta
     5521 gtaaatcaaa actttcattt gtaccaactt actatacaag agaatttttt gcattatgga
     5581 aaacaatcat ttttgataga taataaataa aaagactaga tataaactca tatctagtct
     5641 tttctattcc cttaattcta atccattttc caactttact tgttgtagaa atttcaatat
     5701 tgggatttac aagtaattgc ttataagaag ttttatattt ttcgattcca aaatataatt
     5761 ttccttcata atccattata aatccaaatg gtcttactct tggtttatta tcttcaactg
     5821 tagcaaaata gaatgttgag ttttctttta aaaaattcat tattttttca tgattaaatc
     5881 ctctttgtat cttatactaa tataatgaat ataaataaaa tattcattat acttaatata
     5941 aatcgatata aaaacaatta caatattata ttgattattc gaaattatat ataaaattca
     6001 gaaaaaattt tagtttacat aacaaaaata aagtcaacta aaattattga ttttagatta
     6061 aagtaccgga ttaagcattt aagtagattt taagcttgat ttgattggaa aggtacaaac
     6121 ta
//
LOCUS       DAJMZY010000160         6118 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.165, whole genome shotgun sequence.
ACCESSION   DAJMZY010000160 DAJMZY010000000
VERSION     DAJMZY010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6118)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6118)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6118
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.165"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            190..1554
                     /locus_tag="OE968_003546"
     CDS             190..1554
                     /locus_tag="OE968_003546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase"
                     /protein_id="HCP7220779.1"
                     /translation="MDIKELVKMQRKYYNTGKTRDISFRIEQLKKLKLVVSQNEEKIL
                     LALKKDLNKSDFEGFMTEVGMFYSELNFAIKNIRKWSKIKRVKSSMVNFPSISKVVPQ
                     PYGVTLIMSPWNYPFQLALIPLVWSLVAGNCVILKPSEYSVSTSSVVKDIVEDTFSKE
                     YVAVVQGSQEESEKLLLERFDYIFFTGSTNVGKIIMKSASEHLTPITLELGGKSPCII
                     LKDANIDLTAKRLTWGKLINAGQTCVAPDYVLVHEDRKNELIEKIKYYTNKYFGDNPC
                     NNEQFPKIINQRHFNRILSLIDKDKIVYGGNYNKETLKIEPTIVDNVNWDDNIMKEEI
                     FGPIFPILTYKDLDEVIQKIIQMPNPLALYIFTKNKYLENKLLEMIPAGGCCINDTVT
                     HIATNYLPFGGIGESGMGSYHGKAGFDTFTHYKSVLKKLNLDVPIRYAPYDNKLIKVL
                     KKIM"
     gene            1693..2859
                     /locus_tag="OE968_003547"
     CDS             1693..2859
                     /locus_tag="OE968_003547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HCP7220780.1"
                     /translation="MKINWNTKYTTIAIYTFIIAASSIIFYLVSSQIDVFSNNLDAIF
                     TTLQPFIIGFAIAYLLNFILKFYEDRIFIKSEKLKKLKQSSKRGLGLLLTYATATLIL
                     YLFMHFVLPQVIESIVGLANDIPMYVNNATKLIDKLMTDLNLDEQYFNLAVDKWNEFV
                     TYIIKFVTDLIPILGSMLKNVASSIWNIVLGLIVSVYLLIDKEKFYGLSKKITYAVFT
                     EKQAARILELTHRSNYTFGRFLGGKILDSFIIGILTFVILTLVKMPYTLLISVIIGIT
                     NIIPFFGPLFGAIPSTLIVMFVSPIKAFWLLLIILIIQQIDGNIIGPKILGDSIGISA
                     FWILFSLLVAGKLLGFIGMVIGVPMFAVIYSIIKDIVESKLDKKGLPTDTSDYM"
     gene            2976..3758
                     /locus_tag="OE968_003548"
     CDS             2976..3758
                     /locus_tag="OE968_003548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HCP7220781.1"
                     /translation="MAFIECKFKSKYTGGETDIIVILPVANGKELFSGKEIYDFEGKF
                     KTLYLFHGLEDDQSSWIRYTNVEHYAKNKNIALVIPRVETSFYTDMAYGHQYFTFVSE
                     ELPKFVRAIFPLSDKREDNFVAGMSMGGYGALKLALSKPKEFSAVASFSGSPDMIHEL
                     ENQQIETNADILFHDFGRPEDARNSENDLLYILKNLKERNEDIPKIYQFCGDRDFLYK
                     NNQMFKKYADSLGVDVEYEECVGGHEWRLWNLWIKKFIDIIG"
     gene            complement(3877..4530)
                     /locus_tag="OE968_003549"
     CDS             complement(3877..4530)
                     /locus_tag="OE968_003549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCP7220782.1"
                     /translation="MSKSEKGKETKASIISAARELFFEQGYHKTTTRQIAERANINLG
                     LISYYFSSKSEIGAIIYEDIRNEMQSLIYNYHEEGTMMMFFLAMNADLCFLLKNEAYR
                     NFYLDIAYEEAILSYQRSVTEMVMKRYVNDKESIEHDELILSCIGILAMKPEIIRVYT
                     SHKYDISSQAVIKHFTKQFLINLGHSTDLCEEILEELSKYYIDIVDNFTPIITRVRT"
     gene            complement(4554..5918)
                     /locus_tag="OE968_003550"
     CDS             complement(4554..5918)
                     /locus_tag="OE968_003550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter family protein"
                     /protein_id="HCP7220783.1"
                     /translation="MLLLIVTCAIYIWIGFYFSKKVKTASDFLIAGRNLPLPILAATI
                     AATSFGGGCLVGGVQWGAERGLWVGMYSTIGAALACFINAFFAGKLRSLSCDITPADY
                     IETRYGHSVFLRAYQSLVTPISILAIMGSQLISFGSVSTAFGIPYDIAVIIGVIVIII
                     YTYTSGMWGVAVSAFIQLAICIVFLPIVAYISLKLVGDNPLLMLQSMVKEPFFPGNKS
                     ISDFMYTVLPLVLGSIFSYESFLRYQCADNAKNAVKSSVIAGFILLFLAFPIGIIGAI
                     GGSLFPNISSVQVLPQMISTTLPPLISVLFLAAILAAIMSTADSLMTSMSAIISRDIY
                     NKLLHPNIEFNDLKNTLKYSQIASALTAIIGAIIALKFDSLLELLFWPAPLCTGVIFA
                     PFVIGLCWKGATKKGAIYAVIVSVILALLNMIGILTVFDRILVPIIGGSITIFIVSKF
                     SKKD"
BASE COUNT         2305 a          759 c          925 g         2129 t
ORIGIN      
        1 ttaaaaaatg tttattttaa aataaattat tttataagct tacttatact taataagggg
       61 ctttttttat tggaagattt atgttatatt gagatgaatt tattatgata taaaaaataa
      121 tgttaggata aatttaaatc tttttctaaa aatgtattaa tataattctt aaagaaagga
      181 tttttaataa tggatataaa agagttagtt aaaatgcaaa gaaaatatta taatacaggt
      241 aaaacaagag atatatcgtt tcgtatagaa cagttgaaga aacttaagtt agttgtatca
      301 caaaatgaag aaaaaatact tttagcacta aagaaagatt taaataaatc ggattttgaa
      361 ggttttatga cagaagtagg catgttttat agtgaattaa actttgctat aaagaatata
      421 agaaaatgga gcaaaataaa aagagttaaa tcaagtatgg ttaattttcc atctatatcc
      481 aaagttgttc cacaacctta tggtgttact ctcataatgt caccttggaa ttatccattt
      541 caattagcac ttataccatt agtttggtca ttagtagcag ggaattgtgt tatattaaaa
      601 ccttctgaat attctgtgtc aacatctagt gtagttaaag acatagtgga agatactttt
      661 tcaaaagaat atgttgcagt tgttcaagga agtcaagaag aaagtgaaaa gttactattg
      721 gaaagatttg attatatatt ttttacagga agtactaatg ttggtaaaat aatcatgaaa
      781 tcagcatcag agcatttaac tcctattact ttagaacttg gaggaaaaag tccttgtatc
      841 attttaaaag atgctaatat agaccttact gccaaaagac ttacttgggg aaaactaata
      901 aatgcaggac aaacctgcgt ggctccagat tatgttttag tgcatgaaga tagaaaaaat
      961 gagttaatag agaaaataaa atattatact aataagtatt ttggagataa tccatgtaat
     1021 aatgagcaat ttcctaaaat cataaatcag agacatttta atcggatatt atctcttatt
     1081 gataaagata agatagtcta tggtggaaat tataataagg agacattaaa gatagagcca
     1141 actatagtag acaatgttaa ttgggatgat aatataatga aggaagaaat atttgggcct
     1201 atatttccca ttttaacata taaagattta gatgaagtaa tacaaaaaat tatacaaatg
     1261 ccaaatccat tggcacttta tatttttaca aaaaataagt acctagaaaa taaactttta
     1321 gaaatgattc cagcaggcgg atgttgtatc aatgatacag ttactcatat agctacgaat
     1381 tacttacctt ttggtggtat tggtgaaagt ggtatgggct catatcatgg aaaagctgga
     1441 ttcgatacat ttactcacta taagagtgtg ttaaaaaaat taaatttgga tgtccctatt
     1501 agatatgctc catacgataa taaattaatt aaggttctta aaaagataat gtaggttata
     1561 ttgtagaata ataaatataa ataaaattga gtatttgtat tctgaatata ttttattttt
     1621 aatttggtat atttgttata aaagtggtga ttttgtgata aaatttaatt atatagaaat
     1681 aaggaggaaa aaatgaaaat taattggaat acaaaataca caacaatagc aatttataca
     1741 tttataatag ctgctagtag tattatattt tatctagtat catcacaaat tgatgtattt
     1801 tctaataatt tagatgctat atttacaaca ttacaacctt ttataatagg atttgctatt
     1861 gcatatcttc ttaattttat tttaaagttt tatgaagaca gaatttttat aaaaagtgag
     1921 aaattaaaaa aactaaaaca aagttcaaaa agaggcttgg gtcttttatt aacatatgca
     1981 acagctacat tgatacttta cttatttatg catttcgtat tgccacaagt aattgagagt
     2041 attgttggac tagcaaatga tatacctatg tatgtaaaca atgcaactaa gcttattgat
     2101 aaattaatga ctgatttaaa tcttgatgag caatacttta atttggcagt tgataagtgg
     2161 aatgagtttg ttacatatat tataaagttt gtaacagatt taatcccaat attaggaagt
     2221 atgttaaaga atgtagcctc tagtatatgg aatattgtac taggattaat tgtttcagta
     2281 tacttattaa ttgataaaga aaaattctat ggattaagca aaaaaataac ttatgcagta
     2341 tttacagaaa aacaagctgc cagaatttta gaattaactc atagaagtaa ctatacattt
     2401 ggaagatttt taggtggcaa aatattagat tcattcatta taggtattct aacatttgta
     2461 atacttacgt tagttaaaat gccatataca ttattaatat cagttataat tggtattaca
     2521 aatattatcc ctttctttgg acctttattt ggagctatac catctacgct aatagtgatg
     2581 tttgtatctc ctataaaagc tttctggtta ttgttgatta tattaataat acaacagata
     2641 gatggaaata ttataggacc taaaatactt ggagattcaa ttggtatatc tgcattttgg
     2701 attttgttct ccttattggt tgcaggaaaa ttattaggtt ttattggaat ggttatagga
     2761 gttccaatgt ttgcagtaat ttattctata attaaggata ttgttgaaag taaattggat
     2821 aaaaagggat taccgacaga tacttccgat tatatgtagc taaaaaatat tatgtataat
     2881 taaaaatata taaattaagc aatatttaaa gcactgagaa agttaaactc ttggtgcttt
     2941 ttagatataa aattattata gaagaggtgt tttttgtggc atttatagaa tgtaaattta
     3001 aatctaaata tactggagga gaaactgata taattgtaat tttgcctgta gcaaatggaa
     3061 aagaactttt tagtggtaaa gagatatatg attttgaagg taaatttaaa acattatact
     3121 tatttcatgg tttagaagat gaccaaagct catggattag atatactaat gtagagcatt
     3181 atgctaaaaa taaaaatata gccctagtaa taccaagagt agaaactagt ttttataccg
     3241 atatggcgta tggacaccaa tattttactt ttgtaagcga ggaattacct aaatttgtta
     3301 gagctatatt tcctttatca gataaaaggg aagataactt tgtagctggt atgtctatgg
     3361 ggggatatgg agctttaaaa ttagcgcttt caaaaccaaa agagttttcg gcagttgcaa
     3421 gtttttctgg ttcgcctgat atgattcatg agttagaaaa tcaacaaata gaaaccaatg
     3481 cagacattct atttcacgat tttggtagac cagaagacgc tagaaatagt gagaatgatt
     3541 tactttacat acttaagaac cttaaagaaa gaaatgaaga tattcctaaa atttatcaat
     3601 tttgtggtga tagagatttt ttatataaaa ataatcagat gtttaaaaaa tatgcagatt
     3661 ctctgggtgt agatgttgaa tatgaagagt gtgtaggggg gcatgaatgg cgtctttgga
     3721 atttatggat aaagaaattt atagatataa ttggatagta cacttatggt attaacaggt
     3781 atactataaa atatctttaa atatgataaa gactgaaatc ctaaaatcaa attatgattt
     3841 taaaatttca gtctctaaga atttaataaa attttattaa gttcttacac gagttattat
     3901 tggagtaaaa ttgtcaacta tatctatata gtatttactc aattcctcta aaatctcttc
     3961 gcataaatcc gtactatgac caagattaat aagaaactgt tttgtaaaat gctttattac
     4021 agcttgagaa gatatatcgt acttgtgtga agtataaact ctaattattt caggtttcat
     4081 agcaagtata ccaatacaag aaagtattaa ttcatcatgt tctatagatt ctttatcatt
     4141 aacatatctt ttcatgacca tttcggttac acttctttga tagcttaaaa tagcttcttc
     4201 ataagctata tccaaataaa aatttctata tgcttcgttt tttagaagga aacaaaggtc
     4261 agcattcata gcaagaaaga acatcatcat agtaccttct tcatggtagt tatagattaa
     4321 agactgcatt tcatttctta tatcttcata tattatagct cctatttcgc ttttacttga
     4381 gaagtaatag cttattagac ctaaatttat attagctctt tctgcaattt gcctagttgt
     4441 tgtcttatga taaccttgct caaaaaataa ttctctagca gcacttataa tactagcttt
     4501 tgtttctttg cccttttctg attttgacat atttactgtg tatacctctc ttttcaatct
     4561 ttttttgaaa atttgctaac tataaatatt gtaatagaac cacctattat aggaaccaaa
     4621 attctgtcaa atacagtaag aataccaatc atatttaata atgccaatat aacacttact
     4681 ataacagcat agatagctcc tttttttgta gcacctttcc agcaaagacc aattacaaat
     4741 ggtgcaaata ttacacctgt acataatgga gctggccaaa acaataattc taataaacta
     4801 tcaaatttaa gtgctatgat tgcacctatt atagctgtca aagctgatgc aatttgagaa
     4861 tactttagag tattttttaa atcattaaat tctatattag gatgtaataa tttgttataa
     4921 atatctcttg atataatagc actcattgag gtcattaatg aatcggcagt agacattatg
     4981 gcagccaata tagcagctaa gaataataca gatattaaag gtggcaaagt agtcgatatc
     5041 atttgaggta aaacctgaac agatgatata tttggaaata aactaccacc aatagctcca
     5101 attattccta tagggaaagc aagaaataat agtataaatc ctgcaattac actactttta
     5161 actgcatttt tagcattatc agcacattga tatcttaaaa aactttcata agaaaatatt
     5221 gagcctaaaa ctaatggtaa aactgtatac ataaaatcac taatcgattt atttcctgga
     5281 aagaatggtt cttttaccat tgattgtaac ataagtaaag ggttgtcgcc aactaatttt
     5341 aagcttatat aagctactat tggcaaaaac actatacaaa tagcaagttg aataaatgct
     5401 gatactgcaa ctccccacat tcctgatgta taagtatata taatgataac tataactcct
     5461 ataattacag ctatatcata aggaatacca aatgcagtag atacagaacc aaaagaaatc
     5521 aattgactac ccataatagc tagtatagat attggtgtta caagactttg ataagctctt
     5581 aaaaatacac tatgaccata tctagtttca atataatcag caggtgttat atcacaagat
     5641 aagcttctta attttcctgc gaaaaatgca tttataaagc aagctaaagc tgcacctata
     5701 gtagaataca ttccaaccca aagtcctctt tcagctcccc attgaactcc accaactaag
     5761 caccctcctc caaaagatgt agcagcaatg gttgcagcta gtataggcaa aggcagattt
     5821 ctacctgcga ttaggaaatc ggatgctgtt ttaacttttt ttgaaaaata aaaaccaatc
     5881 catatgtata ttgcacacgt aacaattaaa agtaacatag tcttttctcc tttataaaat
     5941 attttaataa aatatacaaa atatatttaa aatatatttt atataaaagt agtacgatat
     6001 ttgttttatt ggttttagat taatatagct ataataattt atgatattag atggaaatta
     6061 cgtaaaaata gaaaattgaa aattctgaaa tttttgtata ttgatattta tctcatag
//
LOCUS       DAJMZY010000161         5805 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.166, whole genome shotgun sequence.
ACCESSION   DAJMZY010000161 DAJMZY010000000
VERSION     DAJMZY010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5805)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5805)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5805
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.166"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            176..553
                     /locus_tag="OE968_003551"
     CDS             176..553
                     /locus_tag="OE968_003551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HCP7220784.1"
                     /translation="MMIRKIPQAELKVMKFIWKVDVTVTSKDVIEAMEQKYGWKQTTT
                     LTLLSRLVKRGFLDAQKIDRYTHYTIRVKHKDYLSFETKDFLSNIHDDSLRSLISALH
                     DDENIGKDKLDFLESYFDNLKDE"
     gene            546..1694
                     /locus_tag="OE968_003552"
     CDS             546..1694
                     /locus_tag="OE968_003552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protease"
                     /protein_id="HCP7220785.1"
                     /translation="MNNYMLYVFENLIKTTIVCSLGICLLLFLKRYLFKKFSKRFNYY
                     IWLIIVFRMLLFLFNYTIVYEVKEPKENALGNNITQIDISTDNNLMLYVAYLWLFVTI
                     VIAVYTFIKYTRFKNLVVDVSYDIEDNDINCIYKNLLKELNIKKKIELRGSDELISPA
                     GMGLFKSYIFLPDYPYSKDELTWILKHELMHFKNKDILIKFLVLSVRIIYWFNPLVYV
                     MSNKVNLDCELCCDESVLVECSLKDKKEYALALIKSIKFSKNYNSKILTTEFDKTNLE
                     KRLESIVKKKGKSGILIAVLVFMTSITSFVEVDAQVRIDEGNNGMNNNINEFLLNKTT
                     DKIINIYYKDAPNEIRKFYEDKCELEGKIPRDYDIIEMDMKDYNQLIK"
     gene            1711..2313
                     /locus_tag="OE968_003553"
     CDS             1711..2313
                     /locus_tag="OE968_003553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan-binding protein"
                     /protein_id="HCP7220786.1"
                     /translation="MLTKLRKIVAIMCCLLLTFTSVAFADTSKEKGGSKETVPEKNLD
                     SFTLSGYIYTYENAPQEIRDEHKQNCEEINIDPKPDDEIFVPESANLMNEDNSKGVYA
                     SYTVSYNIGAKTITIMSNEYLTISTTKVIRKGNSGKEVKAAQIMLTLLGYNVGIDSSF
                     GSKTYNAVVSFQKKYGLSADGIIGPATWDKLGRLTDPTLS"
     gene            complement(2406..3428)
                     /locus_tag="OE968_003554"
     CDS             complement(2406..3428)
                     /locus_tag="OE968_003554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HCP7220787.1"
                     /translation="MDYNDLLKSARENFNGTCKVCKICNGLACAGDVPGMGGKGSGSS
                     FIENRKSLEKIKINMRVIHNVSKPDTSIELFGRKMSSPIFAAPVSGTILNMGGKVSEK
                     EYIEPVVRGCSNSGIYAMVGDTNVDTFLLDNLDVLKDNRGNGIVFIKPWNNSKIIDKI
                     RLSEEAGAFAVGVDLDACGLINNQFQENPFSPKTIDEIRELVESTRLPFIIKGIMTVD
                     DALMAVESGASAIIVSNHGGRVLDYTPGTCEVLPDIAKSVKGKITILVDGGVRTGVDV
                     VKMLGLGADAVLMGRPFVTASFGGGLDGVEFFIEKVRNELCETMILTGCQNVKDIDGR
                     VIWNLL"
     gene            complement(3757..3939)
                     /locus_tag="OE968_003555"
     CDS             complement(3757..3939)
                     /locus_tag="OE968_003555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220788.1"
                     /translation="MYKDKSDECIHLMTAYIDSISGYYSFIDTQLEDFMMKYGENIVD
                     SNLHSIMMLLCKWGLS"
     gene            4252..4671
                     /locus_tag="OE968_003556"
     CDS             4252..4671
                     /locus_tag="OE968_003556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3785 domain-containing protein"
                     /protein_id="HCP7220789.1"
                     /translation="MSLYKFIYDDKEYLLKEENCSALINDEENPVQGVSISKIIDILN
                     EAEEVDFDVEYYQEACPLCLEGVKEKKKFFPFLEYHFYIFSKDGEYVISNISVDYKGL
                     SFNKLSRANKVDNSYIVSVIICENCQDYIVQIENCIV"
     gene            4802..>5805
                     /locus_tag="OE968_003557"
     CDS             4802..>5805
                     /locus_tag="OE968_003557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HCP7220790.1"
                     /translation="MEEIDDTILDSMFKLTLNERLLTNNDFIENKIDVVKNLIDCYKT
                     EQNSLMLLKSNFLLALLYGIQGFSEKMKEYILISCKYIDKCLPKDYKFLARFYSQIAI
                     LSLKNEDVNKANLYMDKFNLICDENNFLIEEIIFKSQLIYIKASKCIESSVIIKEIET
                     LYIKIKEINDFNCKKIYFFIIGKIYFLFLDDALIAKVNFLKARKYADLLKDMQVSSLC
                     NIKIGECECSFENYECSMEYFNEVISNKKYRNVNIIQKYRASNNITKILIKTRNYPVA
                     INNLAKSEVYLEKIKNHSLKEVEKFDLFISLAMYYAKSNEKSFEQSICYLDRAKNILN
                     "
BASE COUNT         2320 a          670 c          826 g         1989 t
ORIGIN      
        1 tatgtaaaaa gtaaaatatt taaatagata tattttaaaa tctaactttt aatattgtaa
       61 aaaaattaga aatttaacaa aaagtacaaa aattcacatt tttttcataa agtgtttgac
      121 taaaaaattc acatgttgta gaattaaggt agcaggagtt ttgagggagg tgtaaataat
      181 gataagaaaa ataccacaag cagaactaaa agtaatgaaa ttcatttgga aagtagatgt
      241 tacagtgaca tcaaaagatg ttattgaagc tatggaacaa aaatatggct ggaaacaaac
      301 caccacactg acacttttat ctaggctggt aaaaagagga ttcttagatg ctcaaaaaat
      361 agacagatat acacattaca caataagagt aaaacacaaa gattatttaa gttttgagac
      421 aaaggatttc ctaagtaata tacatgatga ctctttaaga agcttaattt cagcattaca
      481 tgatgatgaa aatataggta aagataagct agattttcta gaaagttatt ttgataattt
      541 aaaggatgaa taattatatg ctatatgttt ttgaaaatct tataaagaca actattgtat
      601 gtagtcttgg tatttgtcta ttattatttt tgaaaagata tttatttaag aagtttagta
      661 agagattcaa ttattatatt tggttgataa tagtctttag aatgttactt tttctattta
      721 attatacaat agtgtatgaa gtaaaagaac ccaaagaaaa tgcattagga aataatatta
      781 cacaaattga tatttctaca gataataatc ttatgctgta tgtagcttat ttatggttat
      841 ttgtaactat agtcattgca gtttatacat ttataaagta tacaagattt aaaaatctag
      901 ttgttgatgt atcttatgat attgaagata atgatataaa ctgtatctac aaaaacttgt
      961 taaaagaatt aaatataaaa aagaaaattg aattaagagg ttctgatgaa ttgataagtc
     1021 cagcaggtat gggattattt aaatcttaca tattcttacc agactatcct tatagtaaag
     1081 atgaactaac ttggattttg aaacatgaat taatgcattt taaaaataaa gatattttaa
     1141 taaagttttt agttttgtct gttagaataa tatattggtt taatccactt gtatatgtaa
     1201 tgagcaataa agtaaatcta gattgtgaat tatgttgtga tgaaagtgtt ttggtagaat
     1261 gttctttaaa agataaaaaa gaatatgcac tagcacttat aaagtcaatt aagtttagta
     1321 aaaattataa tagtaagatt ttgacaaccg agtttgataa gacaaatttg gaaaagagac
     1381 ttgagagtat tgttaaaaag aaaggcaaaa gtggaatact aattgctgtt ttagtattta
     1441 tgacttctat aacatctttt gttgaagttg atgctcaagt tagaattgat gagggtaata
     1501 atggaatgaa taacaatatt aatgaatttt tattgaataa gacgactgat aaaattataa
     1561 atatttatta taaagatgca ccaaatgaaa ttaggaaatt ttatgaagat aaatgcgaat
     1621 tagaaggtaa aatacctaga gactatgaca taatagaaat ggatatgaaa gattataatc
     1681 aattaataaa ataattataa ggaggatttt atgttaacaa aattaagaaa aatagtagct
     1741 attatgtgtt gcttattgct tacttttaca agtgtggcat ttgctgacac aagtaaagag
     1801 aaaggaggaa gtaaagagac tgttccagag aaaaacctag attcttttac tctttctggg
     1861 tatatatata catatgaaaa tgcgccacaa gaaataagag atgaacataa acaaaattgt
     1921 gaagagataa atatagaccc taagccagat gatgagatat ttgttccaga atcagctaat
     1981 ctaatgaatg aggacaatag taaaggtgtt tatgcaagtt atactgtttc ttataatata
     2041 ggtgctaaaa ctataacaat tatgagtaat gagtatttga ctataagtac aacaaaagtt
     2101 atacgaaagg gtaatagcgg aaaagaagta aaagctgcac aaatcatgtt aactttactt
     2161 ggttataatg taggtataga tagttctttt ggaagtaaga catataatgc agttgtaagt
     2221 ttccaaaaaa aatacggttt gtctgcagat ggaataattg gtccagctac ttgggataaa
     2281 ttgggtagac taactgaccc tactctttca taggattaaa atctaaaaat atattaaata
     2341 gtgtctcaat atgatttttc aatttaaatg agacactatt taaatataaa tgttataaaa
     2401 ctattttaca ataaattcca tataactcta ccatctatat ccttaacatt ttgacaacca
     2461 gtcaaaatca tagtctcaca taactcattc ctaaccttct ctataaaaaa ctccacacca
     2521 tcaagaccac cgccaaaaga agcagtaaca aaaggtcttc ccatcaaaac agcatcagca
     2581 cccaatccaa gcatcttaac tacatcaaca ccagtcctaa ctccaccatc aacaagtatt
     2641 gttatctttc cctttacaga cttagctata tctggaagta cctcacaagt accaggagta
     2701 taatcaagta ctcttccacc atgatttgaa acaataatgg cactagcacc agactctaca
     2761 gccatcaaag catcatctac agtcataatt ccttttataa taaaaggtaa tctagtggat
     2821 tcaaccaatt ctctaatctc atcaattgtt ttaggagaaa aaggattttc ttgaaattga
     2881 ttattaataa gtccacaagc atcaaggtct acaccaactg caaaagcacc tgcttcttca
     2941 gacaatctaa ttttatctat tatctttgaa ttattccaag gctttataaa tacaattcca
     3001 tttcccctat tatccttcaa tacatctaaa ttatccagta aaaaagtatc tacattagta
     3061 tcgccaacca tagcataaat tccagaatta gaacaacctc taacaacagg ctctatgtat
     3121 tctttttcgg aaactttacc acccatgttc aatatagtac ctgatacagg tgcagcgaat
     3181 ataggagaac tcatttttct accaaataat tctatggatg tatctggctt tgaaacatta
     3241 tgtatgactc tcatatttat ctttattttt tctagacttt ttctattttc aatgaaagac
     3301 gaaccacttc ctttaccacc cataccagga acatctccag cacaagctaa tccattacaa
     3361 attttacata ctttacatgt tccattaaag ttctctctag ctgattttag taagtcattg
     3421 taatccatac aaaatctctc ctttttataa tattaaaatt gagtattact atattgaaaa
     3481 tatcttaatt gtaaatatag ggatgttatt atgatgagct aaactagata atacatatta
     3541 gatatttttt attgttgtag atagttaaat tatatcatat tagatagtca aattttgaaa
     3601 aaaactaact tatttaagta tacattttga aaaaattaaa aaagctatat atagattttt
     3661 aaagaaatct atatatagct tttaagttta tgtcaatctt ttttgttaat gaataaataa
     3721 tatagaatac aatatacaaa aaagtttctt gaaatgctaa gataatcccc atttacaaag
     3781 caacatcatt atactgtgta aatttgaatc aacaatgttt tcaccatatt tcatcataaa
     3841 atcctctaat tgtgtgtcaa taaatgaata atatccactt atactatcga tgtatgcagt
     3901 cattaagtgt atacattcat cacttttatc tttatacata tatatctccc cctatataca
     3961 atatataaat ttagatacca aatcgtatca tattaaatag ttaagtgtgt aacatctatg
     4021 cagttatata tttatatcat tatattaata actaaagtga gttttgacaa tagattttgg
     4081 gaaactggat gttcaaagtg caaacttgga ttttaaaatc attaattaag atagcgcata
     4141 ggaatatatg tatacataac ttaattataa agattataaa caattacttt tattaacttt
     4201 atttaaatgg tagaataact tggagattaa taattataag gaggatataa tatgagttta
     4261 tataagttta tatatgatga taaggaatat ttattaaaag aggagaactg tagtgcttta
     4321 ataaatgatg aagaaaatcc agttcaagga gtaagtattt caaaaataat tgatatactt
     4381 aatgaagcag aagaagttga ttttgatgta gaatattatc aagaagcatg tccattatgt
     4441 ttagaaggag taaaagaaaa gaaaaaattc tttccttttt tagaatatca cttttatatt
     4501 ttcagtaaag atggagaata tgtaataagc aatatatctg ttgattataa aggactatct
     4561 tttaataaac tatcaagggc aaataaagtt gataatagtt atattgtaag tgtgataatt
     4621 tgcgaaaatt gtcaggatta tatagttcag atagaaaatt gtatagttta gtgtaaagta
     4681 tgtcttaatt taagagaaat ttctaaattg agacatcaac ttttttcaaa aatagtatgg
     4741 aaaattacta aatttatgag ataatgtaag tcggaggtga gttacaatat atagtaaata
     4801 tttggaagag atagatgata caattttaga ttcaatgttt aaactaacct tgaatgaaag
     4861 attattgact aataacgatt ttattgaaaa taaaattgat gtagtaaaga atttaattga
     4921 ttgctataaa actgaacaaa atagtttaat gttattaaaa tcaaattttt tgctagcttt
     4981 attatatggt attcaagggt ttagtgaaaa aatgaaagag tatattttga tttcctgtaa
     5041 atatattgat aaatgcttac ccaaagatta taaattttta gcacgatttt attcacaaat
     5101 agctatttta agtttaaaaa atgaagatgt aaataaggca aatttatata tggataaatt
     5161 taatcttatt tgtgatgaaa ataattttct aattgaagaa attattttta aatcacaact
     5221 tatttacatt aaggcaagta agtgtataga atcttctgta ataattaaag agatagaaac
     5281 gttgtatata aagataaaag aaattaacga ttttaattgt aaaaaaatat atttttttat
     5341 tattggtaaa atatattttt tgtttttgga tgatgctcta attgctaagg taaatttttt
     5401 aaaagcaaga aaatatgcag atttactaaa ggatatgcaa gtatcttcac tatgtaatat
     5461 aaagataggt gagtgtgaat gttcgtttga aaattatgaa tgttccatgg aatatttcaa
     5521 tgaagtaata agcaataaaa agtatagaaa tgtaaatata attcaaaaat atagagcatc
     5581 aaacaacata actaaaatat taataaagac tagaaattat cctgtcgcaa taaataattt
     5641 agcaaaatct gaagtatatc tagaaaaaat taaaaatcat agcttaaaag aagtagagaa
     5701 gtttgattta tttataagtt tagccatgta ttatgcaaaa agtaatgaaa aatcttttga
     5761 acaatcaata tgctatttag atagagctaa aaacatatta aatat
//
LOCUS       DAJMZY010000162         5790 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.167, whole genome shotgun sequence.
ACCESSION   DAJMZY010000162 DAJMZY010000000
VERSION     DAJMZY010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5790)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5790)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5790
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.167"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            complement(<1..1989)
                     /locus_tag="OE968_003558"
     CDS             complement(<1..1989)
                     /locus_tag="OE968_003558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis cyclic di-GMP-binding
                     regulatory protein BcsB"
                     /protein_id="HCP7220791.1"
                     /translation="MKKFIISIISLVLFFSNISLIYKVNADETKVKNYKFERDITIDG
                     VIGSNSTFFEVNKNWDIEEVLLHLNFSKSQILNGDVSSLTVLINNVPIKSIKLNAKTN
                     YKNTLEVLVPKDYIIQGYNEIKIKTYKTISDKICQDDSNTGNWMVIHKESYISIRYKQ
                     KKVENSINEYPYPYAEIENNHKLDTTIVVPDNMTRGETTAVFNLASAFGKITKNDDLK
                     LDVKLYSEMKNWSDDNIIYIGKPENTAEEILDILSIKEQTLLSSNCIIKQVDSPYNKN
                     KKMMVVIGSNEDDLIKASNLLIENRLSNQVLSSSVLVNKETNIKINREQKLNLGHLTL
                     KDLGYSDFLLEGAFNQQALFDVKIPTGKVLDDGSKIILNLRYSDNLDFEKSLVTVSIN
                     DVIVGSKKLDRSHSNNDKLELKIPKDIDNKNYYQVKLTFNLSIKNSNCVTRESNNPWA
                     YVSNNSYLALSMKENETLSFENYPYPFVRDDEFNDLTVIMPDYSGSQAMTWMFRLGVT
                     LGANINSHNGNINVIRGKEFSDKYKDTNIVVFGVPHNNSVIKMLNNNLNIKFDKNYSN
                     FISNDKISFIDDYGKNISTIQLIKSPYNNQKNIMVISSMNEKNLYLGMDYLLNKSKVN
                     DLKGDTLIIDEYGEVEDLAYNLKSKKEVKDSSWNMSINK"
     gene            complement(2012..3268)
                     /locus_tag="OE968_003559"
     CDS             complement(2012..3268)
                     /locus_tag="OE968_003559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003362983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HCP7220792.1"
                     /translation="MRDLNVSEYLFVFSLFSIWSLLLINIILAMGGYIFYFKNFDKEI
                     KEIDEYPMISILVPAHNEAKVIGRTVESLLLLNYPKSKMELIVINDNSSDNSKEILEN
                     IKDRYNNYNFTIINTDSLTGGKGKSNALNIGYTISKGDFIAVYDADNTPDKNALRYLV
                     QTIVMNDELGAVIGKFRTRNKNKNLLTKFINIETLSFQWMSQAGRWQLFNLCTIPGTN
                     FILRRSIIEEIGGWDSKAIAEDTEISFRIYKLGYKIKLVPQSITWEQEPETVKVWIKQ
                     RTRWAKGNIYVLMKYIKNIFKQGRNKIVFDIAYFFSVYFLFLTSVIISDILFVLSISK
                     LVEISIPINFFLIWILSYLLFIIEVSISLTIEKGEATIENIFIVAIMYFTYSQLWLFV
                     AIKGMIEYLKDIIFKREVKWYKTERF"
     gene            complement(3317..4981)
                     /locus_tag="OE968_003560"
     CDS             complement(3317..4981)
                     /locus_tag="OE968_003560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HCP7220793.1"
                     /translation="MMFKIFNKSLLKLVVVLSIVLTISNFSLSSYASEITSSTDKVLI
                     IYDSKKETAYNRDILNIMRTLLGRFSSDIELLKLSNYDGEINKNYYSHIFILGINENS
                     YNNDKNTKNLISSLNSYKGTICWLGYGIENLLEHKKYNLDYVGKTNNIVSVNYRGKSY
                     NLDEHYVFNIVESKDTSNKVIGSINDTLNKYPYIINDKNLFYVSKLDLDGVLFYIFCD
                     SLNDIFNIKTFDKGRIFVRIEDVHAFREPKNLVEIADYLSSKNIPFTIALIPAYVNPK
                     NHKVITLSESPEIVKAIKYMQDKGGTVILHGYTHQYKKEEVSGEGYEFWDGKKDEPLK
                     ENMKIFVKDRVLNGLRVCIENGIYPLAFEAPHYAMESEGYKELKKYFSTYMGQHQNND
                     KKFSTNTYPYIIRDTEEFNIFIPENLGYIDPEDKFTFQNIKENLNKLSIVRGFSGGFF
                     FHSYLNIEYLKNTIEYLEKQNIEFMNLRDFNNWVKVDEIQIRNNGDEIIVNYDKDLDE
                     ITKSDTRFKSISNISKVLIFIVSISVLIFVIIFIYFKRIDKKKFLK"
     gene            complement(4971..>5790)
                     /locus_tag="OE968_003561"
     CDS             complement(4971..>5790)
                     /locus_tag="OE968_003561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HCP7220794.1"
                     /translation="LILALLVFIFLIVGIVILSIRTENKLNVFIMLAIIFFIIMLTYL
                     SNSVVGLITSSIIIFMYTSYILYNNITHNMDVEFISYMWIIATPVSSIIMGNLNKSIN
                     ELQNTNKKLSEQYKELVTIDSETGLRNLKIFYNDVNMEISKSIRHNTDFSLMIVKLPY
                     YGNLQTIFGENKTNKIVKYIGSNIIECTRNEDIIYSLQKDMIGILMPNTSLEGSKVVK
                     DRIKKRIKELNLDLNNRGKYVNIDVKIAFLQYKSSFGDSINFKNIVEEELQYDV"
BASE COUNT         1942 a          908 c          520 g         2420 t
ORIGIN      
        1 cttatttata ctcatattcc aacttgaatc ttttacttct ttcttagatt ttaaattata
       61 agctaaatct tctacctctc cgtattcatc aattatcaat gtatctcctt ttaaatcatt
      121 aactttactt ttattcaaca aataatccat tcctaaatat aagttttttt cattcattga
      181 actaattacc atgatatttt tttgattatt atatggtgat tttattaatt gaatggtaga
      241 aatatttttt ccataatcat caataaagct tatcttatca tttgatataa aattggagta
      301 atttttatcg aattttatat ttaaattatt atttaacatc tttataacag aattattatg
      361 tggcactcca aaaactacaa tattagtatc cttatacttg tcactaaatt cttttcctct
      421 aattacattt atatttccat tatgtgaatt tatattcgca cctaaagtaa cacctaatct
      481 aaacatccaa gtcatagctt gtgaccctga ataatctggc attatcacag ttaaatcatt
      541 aaattcatca tctctaacaa atggatacgg ataattttca aaagataagg tttcattttc
      601 tttcatagat aacgccaaat aagaattatt tgatacatat gcccaaggat tattactctc
      661 tctagtaaca caattcgaat tttttatact caaattaaat gtcaatttaa cttgataata
      721 gtttttatta tctatatctt taggtatttt taattctaac ttatcattat tagaatgtga
      781 cctatccaat tttttacttc ccacaataac atcatttata gacactgtaa ctaaagattt
      841 ttcaaaatct aaattgtcag aatatcttaa atttaagata atctttgaac catcatctaa
      901 taccttaccc gttggtattt tgacatcaaa caaagcttgt tgattaaatg ctccttccaa
      961 caaaaagtca gaatatccta agtcttttaa tgttaaatga cctaaattta atttttgttc
     1021 cctattaatt tttatattag tctctttgtt tacaagtact gatgatgata aaacttggtt
     1081 agaaagtcta ttttctatta ataaatttga tgcctttatt aaatcatctt cattactacc
     1141 aattaccacc atcatcttct tattcttatt gtatggtgaa tctacttgct tgattataca
     1201 gtttgaagat aatagggttt gttcctttat acttaaaata tccaaaattt cttctgctgt
     1261 attttcaggt ttaccaatat atataatatt atcatctgac caatttttca tttctgaata
     1321 taatttaaca tctaacttta aatcatcatt ttttgttatt tttccaaatg ctgatgccaa
     1381 attaaacact gctgtagtct ctcctctagt catattatct ggtactacta tagttgtatc
     1441 taatttatga ttattttcaa tttctgcata tggatacgga tattcattta ttgagttttc
     1501 cacctttttc tgcttatatc taattgatat atatgattct ttgtgaataa ccatccagtt
     1561 cccagtattg gaatcatctt ggcaaatttt atcagatatt gttttgtatg tttttatttt
     1621 tatttcatta tatccttgaa ttatataatc ttttggaact aatacttcta atgtattttt
     1681 ataatttgtc ttagcattta atttaataga ttttattggt acattattta tcaatacagt
     1741 taaacttgaa acatctccat ttaatatttg gctcttacta aaattaagat gcaataaaac
     1801 ttcttcaata tcccaatttt tatttacttc aaaaaaagta ctattacttc ctataacacc
     1861 atcaatagtt atatctcttt caaacttata atttttaact ttagtctcat cagcatttac
     1921 tttgtatata agtgatatat ttgaaaaaaa caatactaaa gatataattg atataataaa
     1981 ttttttcatg ttaattcctc ctgtacatga atcaaaatct ttctgtttta taccatttaa
     2041 cctctctttt aaaaattata tcttttagat actctatcat tccttttata gctacaaaca
     2101 gccatagttg agagtatgta aaatacatta ttgccactat gaatatattt tcaattgttg
     2161 cttcaccttt ttctatagta aggcttatac tcacttctat aataaataaa agataagata
     2221 gtatccatat tagaaaaaag ttaattggaa tagaaatttc tactagttta gatatactta
     2281 aaacaaataa aatatcggat ataattacag atgttaaaaa tagaaaatat acagaaaaaa
     2341 agtaagctat atcaaacaca atcttatttc ttccctgttt aaatatattt tttatatatt
     2401 tcattaatac atatatattc ccttttgccc atctagtacg ttgctttatc cacaccttaa
     2461 cagtttctgg ctcttgttcc catgttatag attgtggtac aagctttatc ttgtatccca
     2521 atttatatat cctaaaactt atttctgtat cttctgcaat tgctttacta tcccatcctc
     2581 caatttcttc tatgatactt ctcctcaata taaagttagt tcctggtatt gtacatagat
     2641 taaaaagttg ccatctacca gcttgtgaca tccattgaaa gcttaatgtt tctatgttta
     2701 taaatttggt taataggttt ttatttttat ttcgagtcct aaatttccca ataacagcac
     2761 ctaattcatc attcattact atagtttgta ctagatatct aagtgcattt ttatctggtg
     2821 tgttatctgc atcataaaca gctataaaat ctccttttga aatcgtatat ccaatattta
     2881 atgcattaga ctttcctttt ccacctgtta aactatctgt atttattata gtgaaattat
     2941 aattgttgta cctatccttt atattttcta aaatttcttt actattatca gaagaattgt
     3001 catttataac aataagttcc atcttactct taggataatt gagtaatagc aaagactcca
     3061 cagttctacc tatcacttta gcttcattat gagcaggaac aagtattgat atcataggat
     3121 attcatcaat ttcttttatt tctttatcaa agtttttaaa ataaaatata tatccaccca
     3181 tagctaaaat aatatttata agcaataaag accatatact aaacagacta aatacgaaca
     3241 aatactctga tacatttaaa tctctcataa atttctccta aaatatttta aaatattgat
     3301 tctaatataa aatcatttat tttaaaaatt tctttttatc tattctctta aaatatataa
     3361 atataatcac aaatattaaa acacttatag atactatgaa tattaaaact ttactaatat
     3421 tggatatgga tttaaatcta gtatcacttt tagttatttc atctaagtcc ttatcatagt
     3481 tgactataat ttcatctcca ttatttctta tttgtatttc atcaactttt acccaattat
     3541 taaaatctct taaattcata aattctatat tctgtttttc taaatattct attgtgtttt
     3601 ttagatactc tatgtttaaa tatgaatgaa agaagaaccc tccactaaaa cctcttacaa
     3661 tggataattt atttaaattt tcttttatat tttgaaaagt aaacttatct tctgggtcta
     3721 tatatcctaa attttcgggt ataaatatat taaactcctc tgtatcccta ataatataag
     3781 gatatgtatt tgtgctaaat tttttatcat tattttgatg ttgccccata taagtagaaa
     3841 aatatttttt taattcttta tatccctctg attccattgc ataatgtggc gcttcaaatg
     3901 caagaggata aattccattc tctatacata ctctaagacc attcaaaact ctatctttga
     3961 caaatatctt catattttct tttaagggtt catctttttt accatcccaa aattcatacc
     4021 cttctccaga aacttcttct ttcttgtatt gatgagtata tccatgcaat atcacagttc
     4081 cacctttatc ttgcatatat tttattgctt tgacaatttc agggctttct gataaagtta
     4141 ttaccttatg atttttagga tttacatatg ctggtattaa tgcaatcgta aatggtatat
     4201 tcttactact taaataatcc gctatctcta caagattttt tggttctcta aaagcatgta
     4261 catcttctat tcttacaaat atacgtcctt tatcaaacgt cttaatatta aaaatatcat
     4321 taagtgaatc gcaaaatata taaaataaaa ctccatctaa atctaatttt gatacataaa
     4381 aaagattttt atcatttatt atatatggat acttatttaa ggtatcatta atacttccta
     4441 ttactttatt acttgtatct tttgattcta caatgttaaa aacataatgt tcatccaagt
     4501 tatatgattt acctctataa tttacactaa ctatattgtt tgtttttcct acatagtcta
     4561 aattgtattt tttatgttcc aaaagatttt ctataccata tcctaaccaa catatagttc
     4621 ctttatatga atttaaggaa ctaatcaagt ttttagtgtt tttatcatta ttatatgagt
     4681 tttcattgat tcctaaaata aatatatgac tgtaataatt tttatttatc tcaccatcat
     4741 agttactcaa ttttaatagc tctatatctg aactaaatct tcccaataga gtcctcataa
     4801 tatttaaaat atctctatta taagctgttt ctttcttaga atcatatatg attaatacct
     4861 tatctgtgct ggaagtaatt tctgatgcat atgaagataa gctaaaattt gatattgtca
     4921 gtactattga taatacaact actaatttta atagactttt attaaatatt ttaaacatca
     4981 tattgaagtt cctcttcaac tatattctta aaatttatac tatctccaaa actactctta
     5041 tattgtaaaa atgcaatttt gacatctata tttacatatt ttcccctatt gtttaaatct
     5101 aaatttaatt cttttatcct tttctttatt ctgtctttaa caacttttga accttccaaa
     5161 gatgtatttg gcattagtat ccctatcata tctttttgta aactataaat tatatcttca
     5221 tttcttgtac attctataat atttgaacca atatatttta ctattttatt agttttgttt
     5281 tcaccaaata tagtctgtag gtttccgtag tatggtaatt ttactatcat aagagaaaaa
     5341 tcagtattat gtctaataga tttacttatc tccatattta catcattata aaaaatcttt
     5401 aaatttctaa gtccagtttc actatcaata gtcactaatt ccttatactg ttcagatagt
     5461 tttttatttg tattttgcaa ttcatttatg cttttgttca gattacccat tataattgaa
     5521 gatactggtg ttgctattat ccacatatat gatataaatt caacatccat attgtgagta
     5581 atattgttat ataaaatata ggatgtatac ataaatataa ttattgaact tgttatcaac
     5641 cccactactg aatttgataa ataagttaac attattataa aaaaaattat tgctaacatt
     5701 atgaacacat tcaatttatt ttctgtccta atcgatagta ttactattcc aacaattaaa
     5761 aatataaaaa cgagcaaagc caatattaat
//
LOCUS       DAJMZY010000163         5766 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.168, whole genome shotgun sequence.
ACCESSION   DAJMZY010000163 DAJMZY010000000
VERSION     DAJMZY010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5766)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5766)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5766
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.168"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            <1..324
                     /locus_tag="OE968_003562"
     CDS             <1..324
                     /locus_tag="OE968_003562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCP7220795.1"
                     /translation="ICIEDLQVKNMIKNHKLSRLISDVSWSEFIRQLEYKANWYGRQI
                     VKVGKFFASSQICNKCGYKNEEVKNLNIREWICPSCNETHDRDINASINILKEGLRLI
                     TIQNK"
     gene            451..1620
                     /locus_tag="OE968_003563"
     CDS             451..1620
                     /locus_tag="OE968_003563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="HCP7220796.1"
                     /translation="MNELCKDEVVEFCNRIKGKVESVAISGVFAPVNKQQEEEVAKWV
                     REILGDIPISLSNEIGNIGILERENGAILNSALSQVGKAVSLGFEKALKDLGIDAQIY
                     FSQNDGTLMNLEYTMKYPIFTIGCGITNSIRGASFLSKVKNAIVLDVGGTTSDLGVLY
                     NGFPRESSIPVTIGGVHTNFRMPDVLTIGLAGGTCVKGEKDNIKIGPESVGYRITEDA
                     IIFGGDTLTLSDVVTKLDMAFEDRKSNVENLDKEYCNEVYKKVILKLEDAVDQMKTSQ
                     DDVELVLTGGGSIIVPEKLKGISNVIRPPHYTAANAIGAALGQISGDVEKVYSLDKMS
                     REDAIEDAKKEAVNKALKAGAKEDTIEVLNIEDVPLAYLPGNALLIKVKVVGDLI"
     gene            complement(1783..2325)
                     /locus_tag="OE968_003564"
     CDS             complement(1783..2325)
                     /locus_tag="OE968_003564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HCP7220797.1"
                     /translation="MKSYIALLRGINISGKNKIIMSELKASFVELGYSEVSTYLNSGN
                     VVFLSDVDDSKVISNTIRLMIKKQFELEIPVFIISQEELKDILNNAPNWWGDNNKEIY
                     DNLIFMFPDLSYDEFYDEVGNPKEEYEKVYHYKNAIFWSFSRKDYKKTNWWSKTASSN
                     VSDKITIRTANTVRKIVGMR"
     gene            complement(2473..2757)
                     /locus_tag="OE968_003565"
     CDS             complement(2473..2757)
                     /locus_tag="OE968_003565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HCP7220798.1"
                     /translation="MAKNTKQTTVHIDETLLKEVKRIGINENKSISQIINESIIDYIL
                     VYRENEDKEKNEHDKNLNETINEFKKEEEKRMQAKSAARAIAEAKKRVLY"
     gene            complement(2820..3584)
                     /locus_tag="OE968_003566"
     CDS             complement(2820..3584)
                     /locus_tag="OE968_003566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HCP7220799.1"
                     /translation="MNNYLKFATYQLIGFTSSIPRLIKIKKNPDKFSLKEKFEFMQKQ
                     AKKSLDIVNIELNIIGKETLPKEPLLFVVNHSSMLDSFILTASVERPIGCVIADEPVW
                     RNIPIFKEWAKLLRCVYVNRKNNREGIKSIAQASQNILTGQSMAVFPEGDLTWIKEPN
                     SLVSEFRSGALKIAYKAKCPIVPLVIKNSKDTYEGYQPIGKINSVPVEVEFLEPIYDH
                     IENPRLKSSVLGENIKNKMINTIENFRKSNKTFKEF"
     gene            complement(3866..4132)
                     /locus_tag="OE968_003567"
     CDS             complement(3866..4132)
                     /locus_tag="OE968_003567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3795 domain-containing protein"
                     /protein_id="HCP7220800.1"
                     /translation="MIESRCGILCYECGYKEKVNCKGCTEIEKPFWGEQCPVKSCCED
                     KNLTHCGLCDTFPCEMLNQFAYDKEQGDDGKRISQCKKWAVLAL"
     gene            complement(4174..4983)
                     /locus_tag="OE968_003568"
     CDS             complement(4174..4983)
                     /locus_tag="OE968_003568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCP7220801.1"
                     /translation="MNKIINNILNTCKQYTYILPHKLLRQYIAHYTISIPDTSIKENL
                     TLIPDASGCMIFKFDKKGIESAFWGATTKTTIVKNDIENVLFRVFVEFRPGGVYYLTG
                     LSQRESTDLKISLEDFNTLFSLEVNSIFERTSTIEELVEQLDMLFLSYLLKSNIVDMT
                     IPILENARKQNSIMSVKNISQISCYSERHLNRIFNNSLGMSVKSYLRLLRINLVLQEI
                     QNNKIPFATLAQDIGYYDQSHFINDFKSICGVNPTTYIKNLSDFYNEKYKF"
     gene            5296..5577
                     /locus_tag="OE968_003569"
     CDS             5296..5577
                     /locus_tag="OE968_003569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220802.1"
                     /translation="MASKQTPRNNLEKFLRIRVLSHTGDKIHIKLPVNFAKRMIENNA
                     LDLFNGKDDVVDGKKVTEILVKAFDYDLTGEVVHLERKNGDIIKVSIVQ"
BASE COUNT         2074 a          730 c          814 g         2148 t
ORIGIN      
        1 atttgcatag aagatttaca agtaaagaat atgattaaaa atcataaact atctcgctta
       61 atttcagatg tatcatggtc agaatttatt cgtcaattag aatacaaggc taattggtat
      121 ggtagacaaa ttgtaaaggt aggtaaattc tttgcaagtt cacaaatatg caataaatgt
      181 gggtataaaa acgaggaagt taagaactta aatataagag aatggatttg tcctagttgt
      241 aatgaaactc acgatagaga tataaatgca agtataaata tattaaaaga aggattaaga
      301 ctaataacaa ttcaaaataa ataacgtatg taagaaccgg aggaactacg gggatagcct
      361 gtggagaatt agtaagacat attttagtat gcaaaattct gtgaagcagg aaccctgtga
      421 ctttagtcat gggaggttca gggtagaaag ataaatgaac tttgtaaaga tgaagttgta
      481 gagttttgca atagaataaa aggtaaagtg gaaagtgttg caataagtgg agtatttgct
      541 ccagtaaata aacaacaaga agaagaagtt gcaaaatggg ttagagaaat tttaggggat
      601 attcctatat ctttatcaaa tgaaataggt aatataggta tattagaaag agaaaatgga
      661 gctattttaa attctgcatt gtctcaagta ggtaaagctg tatctttagg atttgaaaaa
      721 gcacttaaag acttaggtat agatgctcaa atatatttca gtcaaaatga tggaacatta
      781 atgaatttag agtatacaat gaaataccca atttttacaa ttggatgtgg aataacaaat
      841 tctataagag gagcttcctt cttatcaaaa gtaaaaaatg caatagtatt agatgttggt
      901 ggaactacaa gcgacttggg tgtactatat aatggattcc ctagagaatc atctattcca
      961 gttacaattg gaggagtaca tacaaacttt agaatgccag atgttttaac tattggtctt
     1021 gctggtggta catgtgtaaa aggcgaaaaa gataatataa agataggtcc tgaaagtgtg
     1081 ggatatagaa taactgaaga tgcaataata tttggtggag acactctaac tttatcagat
     1141 gttgttacaa aattagatat ggcgtttgaa gatagaaaaa gcaatgttga aaacttagat
     1201 aaagagtatt gtaatgaggt atataagaag gttattttaa aattagaaga tgctgtagac
     1261 caaatgaaga ctagtcaaga tgatgttgaa ttggttttaa ctggtggagg aagtataatt
     1321 gttcctgaaa aactaaaagg cataagcaat gttataagac ctcctcatta tactgctgca
     1381 aatgctattg gtgcagcttt aggacaaata agtggagatg tagaaaaagt atacagttta
     1441 gataaaatgt cgagagaaga tgccatagaa gatgcaaaaa aagaggctgt aaataaagct
     1501 ctaaaagctg gtgctaaaga agatactata gaagtattaa atatagaaga tgttccactt
     1561 gcataccttc ctggtaatgc acttcttata aaagtaaaag ttgttggtga tttaatttaa
     1621 agaataaata taagtatttc cagaattata taaatatttc tggactcatt tttaaactta
     1681 ttttatcaat aaaaacagca taacttttga ctatattctt ataagtttcc gaacagccga
     1741 tatataccta ttttttgagg tttatcggct gtttgttatc ttttatcgca ttccaactat
     1801 ttttcttacc gtatttgctg tacgaattgt aatcttatca cttacatttg aactggcagt
     1861 ctttgaccac caatttgtct ttttataatc tttacgacta aaagaccaaa agatagcatt
     1921 tttataatga tatacttttt catactcttc tttaggattt ccaacctcat cataaaactc
     1981 gtcataagat aagtcaggaa acataaaaat aagattatca tatatttctt tgttgttatc
     2041 tccccaccaa ttaggagcat tatttagtat atcttttaac tcttcttgtg aaataataaa
     2101 aactggtatt tccaattcaa actgtttttt tatcattaat cttattgtat ttgagataac
     2161 cttgctgtca tctacatcac ttaaaaagac aacattacca ctattaaggt atgtagaaac
     2221 ttctgaataa ccaagttcta caaagcttgc ttttaattca gacataatta tcttgttctt
     2281 accacttata ttgatacctc ttaataatgc gatataactt ttcatataat aatttcacct
     2341 ctaaacattc acatttttct atgtagtaca aactggaatt tgcatctttt ataattcttt
     2401 caaaacttct tcatatgtaa tttttttaat ataaaaaaat cggtgcttaa tttgtaccga
     2461 tttttgtttt tcttagtaaa gaactcgttt ttttgcttct gctatagctc tagcagcact
     2521 ttttgcttgc attctttttt cttcttcttt tttaaattca tttattgttt catttagatt
     2581 cttatcatgt tcattttttt ctttatcttc gttttctctg tatactaata tataatctat
     2641 tattgattcg tttattattt gagatatact tttattttca ttaattccta ttctcttaac
     2701 ttccttaagt agagtctcat caatatgaac cgttgtttgc tttgtatttt ttgccacctt
     2761 aatcacctct taaaaaaaat tctaacatta aaattttttt tagtcaataa attttaatat
     2821 taaaattctt taaatgtttt atttgatttt ctaaaatttt ctattgtatt tatcatctta
     2881 ttttttatat tttcacctag tacagaagac tttagtctag gattttcgat atggtcataa
     2941 attggttcta aaaattcgac ttcgacagga acagagttaa ttttaccaat aggttggtat
     3001 ccttcataag tatcttttga attttttatt actagtggaa caatagggca ttttgcttta
     3061 tatgctatct ttaaagctcc acttctaaac tccgaaacca atgaatttgg ttctttaatc
     3121 catgttaaat ctccttctgg aaacactgcc atactttgac ctgtaagtat attttgagag
     3181 gcttgggcta tactctttat accctcacga ttgttttttc tgtttacata tacacatctt
     3241 agtaattttg cccattcttt aaatataggt atatttctcc aaactggttc atctgcaatt
     3301 acacatccaa ttggtctttc tacacttgct gttagtatga agctgtcaag catactagaa
     3361 tgatttacaa caaatagaag tggttctttt ggcagtgttt ccttaccaat tatattaagc
     3421 tctatgttca ctatatctaa agatttttta gcttgttttt gcataaattc aaatttttcc
     3481 tttaagctaa atttatcagg attcttttta attttaataa gcctaggtat agaagatgta
     3541 aaacctataa gttgatatgt agcaaatttt aagtaattat tcataaaatt atctccttaa
     3601 aataaaatta tttattactg taaagatttt aacataaaat aaaatttaag tctattttaa
     3661 ttcaattttg taacatatat tttaaataga cagagattga gattttatat ttccaatttt
     3721 agtaatcaga ttttatcaat aaattactat tctattaatt taattaaata acctttaaat
     3781 ttaattataa aaactgttgc agaaatttct acaacagttt aaaaaattta ccttacaaaa
     3841 acttatttta taacaagaga gtatattata aggctagtac agcccatttt ttgcactgag
     3901 aaattctttt gccatcatca ccttgttctt tgtcatatgc aaattgatta agcatttcac
     3961 atggaaatgt atcacataga ccacaatgtg taaggttttt atcttcacaa caagatttta
     4021 caggacattg ttcaccccaa aatggtttct caatctctgt acaaccttta caattgactt
     4081 tttccttgta tccacattca taacataaaa ttccacatct tgattctatc attttaagtc
     4141 actccttaaa tataaatttt atatgattgt atatcaaaat ttatactttt cattgtaaaa
     4201 atcggacaaa ttttttatat aggttgttgg attaacacca caaatagatt taaaatcatt
     4261 tataaaatga gattggtcgt aataaccaat atcttgtgct aaagttgcaa atggtatttt
     4321 attattttgt atttcttgta atacaaggtt tatacgaagt aatctaaggt atgatttaac
     4381 actcatacca agagaattat taaaaattct atttaaatgt cgttcactat aacaactaat
     4441 ttgtgaaatg tttttaacag acataataga gttttgtttt ctagcatttt caagaattgg
     4501 tatagtcata tctactatat ttgatttcaa taagtatgat aagaataaca tatctaattg
     4561 ttctactaat tcttctatag tacttgttct ttcaaaaatg gaattaacct ctaagctaaa
     4621 taatgtgtta aaatcttcaa gtgaaatttt taaatctgta gattctcttt gagaaagacc
     4681 tgtcaaataa tatactccac ctgggcgaaa ctcaacgaat actctaaaaa gtacattttc
     4741 tatatcattt tttacaatag tagtttttgt tgtggctccc cagaatgcgc tttctatacc
     4801 ttttttgtca aatttaaata tcatacatcc actagcatca ggtattaatg taagattttc
     4861 tttaatactt gtatctggaa tagatattgt atagtgtgct atatactgtc ttaacaattt
     4921 atgtggcaaa atatatgtat actgtttgca ggtatttaaa atgttattga ttattttatt
     4981 cataagtata tcctcctgat atataaaaaa taagtatact aatttatttt ttatataata
     5041 aaccagtttt gttttaattg aaatattcta ataagatatt ttgttaaatt tagatacaat
     5101 aattgtaaag taaaatctca aaatatacaa ttattataaa tcatagatat ttattaaata
     5161 aatatattaa agaagaagga atataaaaca agattagaaa ataatagtgt tactttcata
     5221 ataaatacat ataaagatat ttttaagaat aaaatttatt attaaataaa aaataaagga
     5281 gagtgattta atagtatggc atcaaaacaa acaccaagaa acaatttaga aaagttttta
     5341 agaataagag tattatcaca tacaggcgat aaaatacata taaagttacc tgtaaatttt
     5401 gcaaagagaa tgattgagaa taatgccttg gatttattta atggaaaaga tgatgtagta
     5461 gatggtaaaa aagttactga aatattagtt aaggcatttg actatgattt aactggagaa
     5521 gtagttcact tggagagaaa aaatggagac attattaaag tttcaattgt acaatagaat
     5581 tattttatat gaattttatt tttgaatagt tataaataat tagaaatttg taaaaaagta
     5641 taatatatta ttagtaatgg tacagaatac acatttataa tttatagatg tgtatttttt
     5701 gtttaaaaaa tttaaatata taaaactata aaggttacaa ttttggaaat agatgtaaat
     5761 atatgt
//
LOCUS       DAJMZY010000164         5661 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.169, whole genome shotgun sequence.
ACCESSION   DAJMZY010000164 DAJMZY010000000
VERSION     DAJMZY010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5661)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5661)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5661
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.169"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            387..590
                     /locus_tag="OE968_003570"
     CDS             387..590
                     /locus_tag="OE968_003570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCP7220803.1"
                     /translation="MISYAPLWKLLIDRKIKKMEFVNISGISISVLGRLGNDKSVSMD
                     TMEKICLALDCKIEDVVEIKKSI"
     gene            754..1908
                     /locus_tag="OE968_003571"
     CDS             754..1908
                     /locus_tag="OE968_003571"
                     /EC_number="1.1.1.267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate reductoisomerase"
                     /protein_id="HCP7220804.1"
                     /translation="MKKISILGSTGSIGKQTLDVVRDNRDKFEIVAISANSNIELLLE
                     QIVEFKPKYVTVFEENKALKLKEMLPKNIEIEVLAGMEGLKIISSLDEVDVLLTAVVG
                     MIGLVPTLCAIKKGIDIALANKETLVTAGELVMKEAEKYNVNILPVDSEHSAIFQCLN
                     GENKKNIEKIILTASGGPFRGKKKGELANITKNEALKHPNWSMGRKISIDSSTLMNKG
                     LEVIEARWLFGVEQENIDVVVHPQSIIHSMVQYTDSSIIAQLGCPDMRLPIQYALTYP
                     DRMESSFERMNFSKFSTLTFEEPDLETFPCLKLAYECLKMGGTYSSVLNSANEVLVSE
                     FLEDKIGFYDIPYYIEKTLEVHSSISEPTLEEILETDRWSRAYVANLIKK"
     gene            1921..2925
                     /gene="rseP"
                     /locus_tag="OE968_003572"
     CDS             1921..2925
                     /gene="rseP"
                     /locus_tag="OE968_003572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HCP7220805.1"
                     /translation="MTIIAALILFSIIVLIHELGHFIFAKRSGIKVNEFSIGMGPKIY
                     SVKKDTEYSIRALPIGGYVSMEGEDEEQISPNSFGNKSILQRFSTIVAGPIFNIILAA
                     ILLVPVFLYIGSPTTKLGKIMPDTPAQAVGLQVGDKINKINGNSVKTWDEVANIINTS
                     SGGELKLSITRDGSDKVVNVTPKNNNGKYEIGIQPQREKDFLGSIVNACKTTVDMTKQ
                     MLTFLGQMITGRVPGGIGNAVAGPVGVIGMVSDAARTGIINVVYLAAVISLNLGIVNL
                     LPIPALDGWRILMLLLEAVRGGKKLDPNKEGMINVVGFGALMLFMLFITYKDILRLFQ
                     "
     gene            3107..4162
                     /gene="ispG"
                     /locus_tag="OE968_003573"
                     /gene_synonym="gcpE"
     CDS             3107..4162
                     /gene="ispG"
                     /locus_tag="OE968_003573"
                     /gene_synonym="gcpE"
                     /EC_number="1.17.7.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin-dependent
                     (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase"
                     /protein_id="HCP7220806.1"
                     /translation="MSYERRKTREVSVGTVKIGGENPISIQSMTNTDTRDADATIAQI
                     KRLEEAGCDIVRVAVPDIKAAKNIAKIKSSVNIPIIADIHFDYKLALEAIEQGVDGIR
                     INPGNIGSIERVKMVVEKCKERNLKIRIGVNGGSLEKELLKKYGSATAEALVESAMGH
                     IKILEDLDFHNIVISLKSSDIYKTVDAYELISKKVDYPLHIGITESGSVHKGTIKSSI
                     GVGALLLKGIGDTVRISLTGDPVEEVIVGKQILRSLGLLNDKIKVISCPTCGRCNIDL
                     ISVVNEVEEKIGSMEKNITVAIMGCAVNGPGEAREADIGIAGGKGEGLLFKKGEIVRM
                     IDGNKLVDELLEEIEKL"
     gene            4510..5334
                     /locus_tag="OE968_003574"
     CDS             4510..5334
                     /locus_tag="OE968_003574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220807.1"
                     /translation="MRYKKISSLPILVVALLITGTTTTFSLSTTNSEKTNVYLANTVS
                     TVTKKVSDIQSSKGLVYNENIPLFINNSKIQYDDTPYHWPSNVISLTNSSEKAIMDYE
                     ITCLAYDKNGKPLELYWDAQNVAADGEVGSVGFSPAGVDYGIVTGISPVSPKSYSHTY
                     RKMQQSPPQDIISMFEKQQGKAWVENWLKEWKQMEKEYAKQNAIAPGKNQNDAFLLFD
                     KWKQSTGEHGVKYIISCVKQVTFNDGSVWKNSAYENWLKSFQGKEVSNSVLENYYK"
BASE COUNT         2204 a          550 c         1033 g         1874 t
ORIGIN      
        1 cctatatcat aacttttttc aaattgatta atttttaata aatacaacat tctttctcct
       61 tttattcaaa atataatttt tataaattta ctaatcttta gcttttttaa ttatatattt
      121 acatatgttt atatgatact ataataatgt gttttaaata gatatataat agtaaatatt
      181 ttttatatag ttatgtttta gtaaaataat gagataaata tatataaagt ttaatttttg
      241 aacttatgct tttgttttat tttaacatat ttatatttaa taaactataa ttgaaatcta
      301 tttagataaa taattattta tctaaataga tgaaaatttt ccaaaataga taaaatgtga
      361 tagaatatat tttgcgaggt gataacatga tttcatacgc tccattatgg aaattgttaa
      421 ttgacagaaa aataaagaaa atggaatttg taaatatatc aggtataagt atttctgttt
      481 taggcagact aggaaatgat aaatctgttt ctatggatac aatggagaag atatgtttag
      541 cactagactg taaaatagaa gatgttgtgg aaataaaaaa gagcatttaa taatactaga
      601 atattttata atattccaca aaatacaaaa aataatagat taattttaat ctgtggaata
      661 atatatgaaa tttctatgaa tagtaaaaat aattgtttta gtagtgttat aatgttttga
      721 cagggtatat ttattattag aaaggattat tatatgaaaa agatatcaat tttaggttct
      781 acaggctcta taggtaaaca aactttggat gtagttagag ataatagaga taagtttgag
      841 atagttgcaa tatcagctaa cagtaatatt gaattattgc tagaacagat agtagagttt
      901 aaacctaaat atgtaacagt ttttgaggaa aataaagcat tgaaattaaa agaaatgttg
      961 cctaaaaata tagaaataga agttttagca ggaatggaag gattaaaaat aatatcatca
     1021 cttgatgaag tggatgtcct tttaactgct gtagtaggta tgataggatt agtcccaact
     1081 ctttgtgcta taaagaaggg aatagacata gcattagcga ataaagaaac gttggtaact
     1141 gctggtgaac ttgtaatgaa agaagcagaa aaatacaatg taaatattct tcctgttgat
     1201 agtgaacata gtgctatatt tcaatgtcta aatggagaaa ataaaaaaaa tatagaaaag
     1261 ataatactta cagcatctgg tggtccattt agaggaaaga aaaagggaga acttgcaaat
     1321 ataactaaaa atgaagcttt gaagcatcca aattggagta tgggaagaaa aataagtatt
     1381 gattcttcaa cgcttatgaa taaaggactt gaagtgatag aagctagatg gttatttgga
     1441 gtagaacaag aaaatataga tgtagtagtt cacccacaaa gcataattca ttcaatggtg
     1501 cagtatacag atagctcaat aattgctcaa ttaggatgtc cagatatgag actaccaata
     1561 cagtatgctc ttacatatcc agatagaatg gaaagtagct ttgaaagaat gaatttttca
     1621 aaatttagta ctttaacttt tgaagaacca gatttagaaa cttttccatg tttaaaattg
     1681 gcatatgagt gtttaaaaat gggaggaact tattcctctg ttttaaattc agcaaatgaa
     1741 gttttagtaa gtgaattttt agaggataaa attggtttct atgacatacc atattacata
     1801 gagaagactt tagaagttca tagtagcata agtgaaccaa cattagaaga aatcttagaa
     1861 acagatagat ggagtagagc ttatgttgca aatctgataa aaaaatagga aggtgaattt
     1921 atgactataa tagccgcatt aatactattt agtataattg tattaataca tgagttagga
     1981 cattttatat ttgcaaaaag aagtggtatc aaagtaaatg agttttctat aggtatgggg
     2041 cctaagatat atagtgtaaa aaaagataca gagtattcta taagagcact tccaattggt
     2101 ggatatgtca gcatggaagg tgaagatgaa gaacaaataa gtccaaattc ttttggaaac
     2161 aagtctatat tacaaagatt tagtactatt gtagcaggac caatattcaa tataatatta
     2221 gcagcaatac ttttagttcc agtatttttg tatataggtt ctccaacgac taaattagga
     2281 aagataatgc cagatactcc tgcacaggct gtagggcttc aagtaggaga taagataaat
     2341 aaaattaatg gtaattctgt taagacttgg gatgaagttg caaatataat aaatacttct
     2401 tctggtggag aattaaaact tagtataact agagatggaa gtgataaagt tgtaaatgta
     2461 acacctaaaa ataacaatgg aaagtatgaa atagggattc aaccacaaag agaaaaagac
     2521 tttttggggt caatagtaaa tgcatgtaaa actactgtag atatgacaaa acagatgcta
     2581 acatttctag gtcaaatgat tacaggacgt gtaccaggag ggattggcaa tgctgtagca
     2641 ggaccagtag gtgttattgg tatggtatca gatgctgctc gtacaggcat cataaatgta
     2701 gtgtatttag cagctgtcat aagcttaaat ttaggtatag taaatctatt accaatacca
     2761 gcacttgatg gatggagaat acttatgctg ttactagaag ctgttagagg tggtaaaaaa
     2821 ctcgacccaa ataaagaagg catgataaat gttgttggtt ttggagcttt aatgttattt
     2881 atgcttttta tcacatataa agatatacta agattatttc aatgatttag tttttagaga
     2941 ttttaagaaa ataggctatg tagttttaaa taagaataaa ttaattttta tatatgaaat
     3001 ttattcttat ttaactagat agctttttaa tttataatat acatgtaggt tataatattt
     3061 taatatttaa agagattcaa tataaaataa tatatagagg tggaatatga gttacgagag
     3121 aagaaagacg agagaagtaa gtgtaggaac tgtaaaaata ggaggagaaa atcctataag
     3181 tatacaatct atgacaaata ctgatacaag agatgcagat gctacaatag ctcaaataaa
     3241 gagattagag gaagctggtt gtgatatagt tagagttgct gttcctgata ttaaagctgc
     3301 taaaaatata gcaaagataa agtctagtgt aaatatacca attattgcag atatacattt
     3361 cgattataag ctagcccttg aagctataga acaaggtgtg gatggaataa gaataaatcc
     3421 tggtaatatt ggaagtatag agagagttaa gatggtagtt gagaaatgca aggaaagaaa
     3481 tttaaaaatt agaattggag ttaatggagg ttctttagag aaagaacttt taaaaaagta
     3541 tggctctgca actgctgaag cattagttga aagtgcaatg ggacatatta agattcttga
     3601 agacttagat tttcataata tagttatatc tctaaaatca tccgatattt ataaaactgt
     3661 tgatgcatat gaattaatat caaaaaaagt tgattatcct cttcatattg gaattacaga
     3721 atctggaagt gttcacaaag gaacaataaa gtcttctata ggggtaggag cacttcttct
     3781 taaaggaatt ggagatactg ttagaatatc tttaacaggc gaccctgttg aagaggttat
     3841 tgttggtaaa cagattttaa gaagtttggg acttttaaat gataagatta aagttatatc
     3901 atgccctaca tgtggtagat gtaatataga cttaattagt gttgtaaatg aggttgaaga
     3961 aaagattggt agtatggaaa aaaatatcac tgttgcaatt atgggctgtg ctgtaaatgg
     4021 acctggtgaa gccagagagg cagatatagg tattgctggg ggtaaaggtg aaggtctttt
     4081 atttaaaaag ggtgaaatag ttagaatgat tgatggtaac aaattagttg atgagttgct
     4141 agaagagatt gaaaaattat agtatacaat tcatatatat attaattgac tagattttta
     4201 aatacttttg taataagttt ttatttacag tatttaatta tctagtcatt ttttatttta
     4261 taaacttcat taaatgtaag aaacttatat tctaatttga ctatatatgt atgagttaaa
     4321 tcatattgta aatttataaa attaaaaaaa gatttaatat agtgaaaatt tccatcaata
     4381 gtattgaaac ttgatagtaa ctatgatagg atatagttac tagaacagtt ggtaaattat
     4441 gttaacatag attttaatgt tttggtaaat tgttttatta taagttaata gaaaaagagg
     4501 tgaagaattg tgagatataa aaaaatatct agcttaccta ttttagttgt tgctttgctg
     4561 attactggaa cgacaacaac attttctctt agtacgacca attcagaaaa aacaaatgta
     4621 tacttagcaa atacggtaag tactgtcaca aagaaggtat cagatattca aagtagtaaa
     4681 ggtcttgttt ataatgagaa tattccatta tttataaata atagcaaaat acagtatgat
     4741 gatactccat atcattggcc tagcaatgtt ataagcttaa caaatagcag tgaaaaggca
     4801 attatggatt atgaaattac atgcttagca tatgataaaa atggaaaacc acttgagcta
     4861 tattgggatg ctcaaaatgt ggcagcagat ggcgaagtag gaagtgttgg atttagccca
     4921 gctggtgtag actatggtat tgttacaggc atatctcctg tgtctccaaa atcatattca
     4981 catacttata gaaaaatgca acaatcacca ccacaggata taataagtat gtttgaaaaa
     5041 caacaaggca aggcatgggt agaaaattgg ttgaaagaat ggaaacaaat ggagaaagaa
     5101 tatgcaaagc aaaatgcaat agcaccaggt aagaatcaaa atgatgcctt tctattgttt
     5161 gataaatgga aacaatcaac tggagagcat ggtgtaaagt acattatatc ttgtgtaaaa
     5221 caagtaacat ttaatgatgg tagtgtatgg aaaaactcag catatgagaa ttggttgaaa
     5281 agttttcaag ggaaggaagt ttcaaatagt gtattagaaa attactataa gtaatgttta
     5341 atgatagcaa aatgagtacg aatttaatta atgttaattt aattaaataa ggactatttt
     5401 gtttaaaaat atcagtgtta caagtaaatt tttattgtga caaaatgata tatatacata
     5461 agattataag catgtgtcaa gttttgatac atgctttttt attttgaata tatgttttct
     5521 ataaatttat gattttttag ttatgtaatt ttatatgtga atttttagat ttttatatag
     5581 atagtgaaat aatgtggaag ttttatgttt taaaaatttt agttaaaaca tttattaaaa
     5641 aagataatag aaatgtttta a
//
LOCUS       DAJMZY010000165         5600 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.170, whole genome shotgun sequence.
ACCESSION   DAJMZY010000165 DAJMZY010000000
VERSION     DAJMZY010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5600)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5600)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5600
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.170"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            54..422
                     /locus_tag="OE968_003575"
     CDS             54..422
                     /locus_tag="OE968_003575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HCP7220808.1"
                     /translation="MENLVKIFKALSDETRLNILILVSKRNICQKGISKYLGISDSAV
                     SQHIKILKDVGIITGYKEGYYVLYHINKESFNICVDFINSMLSNSSESFIDVFDVNTI
                     HLGCSKECKSIKKCCKRREK"
     gene            425..796
                     /locus_tag="OE968_003576"
     CDS             425..796
                     /locus_tag="OE968_003576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NifB/NifX family molybdenum-iron cluster-binding
                     protein"
                     /protein_id="HCP7220809.1"
                     /translation="MKVCIPVEENKGLDSKPYGHFGSAPIFVVCDLESGEVKSLDNGD
                     LDHEHGKCQPLKALSGTAVDAVVVGGIGQGAIIKLNGMGIKVYRAEGDTISANLDLLK
                     NGKLVEFPSDHTCSHDGCGHH"
     gene            complement(941..1396)
                     /locus_tag="OE968_003577"
     CDS             complement(941..1396)
                     /locus_tag="OE968_003577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220810.1"
                     /translation="MNINTVQGDSIEVLLRQLGATRISKVSSTLYFIKFDLGDGWEIS
                     YTYNINAKDQYFLQRIEPYPIGRGLFNDEYEIVSFISKDLKKFLNAKNSSNFKTFVEV
                     TRKVNSIIDNVEELFLNYNVDGDDLKTLNKELNDILNDIDYIEKHTKKI"
     gene            complement(1435..2700)
                     /locus_tag="OE968_003578"
     CDS             complement(1435..2700)
                     /locus_tag="OE968_003578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsB/NhaD family transporter"
                     /protein_id="HCP7220811.1"
                     /translation="MEFQQIIAICIFLIVMAAIITEKVNRSVAAVGGALLMIIFNILT
                     LDEGLSHIDFNTIGVLVGMMLFVAVVKNSGLFEYIAIWTAKKAKGDPWKIMICFAIIT
                     AILSAVLDNVTTVLLIGPMTIVITQILGLNPVPFLITQILASNIGGTATLIGDPPNIM
                     IGSAANLSFMDFVINLGPAVIVILAITIICFRFIYGKELVVNERAKNAILKLDEKKSV
                     KDKPLLIKSLILIAFILFGFMFHSTIHIDSSVVALTGASIMLLIGKQDVDEIMAGIEW
                     STILFFMGLFVVVGGLVEVGIINKLAQALIGLTEGHLVFTMLLILWLSAIVSSFLDNI
                     PFVATLIPLILTMQAEGIDVMPLWWATSLGACLGGNGTLIGASANVVLAGIGNKHGHP
                     ISFKEYFKIGFPLMIISIIISTVYLIIKF"
     gene            3170..4621
                     /locus_tag="OE968_003579"
     CDS             3170..4621
                     /locus_tag="OE968_003579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine:cation symporter family protein"
                     /protein_id="HCP7220812.1"
                     /translation="MDFFNGILTSINNAVVFVNNYLWSYILIIMLVVIGIYFTIKTNF
                     VQFRYFIEMFRLLGDGTANKNAKKEGKISSFQAFCISTSSRVGTGNIAGIAIAVVAGG
                     PGAVFWMWLIALIGSASSFVESTLAQIYKVKDGQAFRGGPAYYMEQGLNKKWMGILFS
                     ILITICYGFVFNAVQANTVSLAFNNAFGISKMAMGIGLGILTAIVIFGGVHRVAKVSE
                     IIVPVFAGLYILVALAIVVMNITEIPSVIALIVESAFDFKGMAIGTFMGVVMTGVKRG
                     LFSNEAGMGSAPNAAATAHVTHPVKQGLIQSLGVFTDTIIICSCTAFMVLLYSGYSSS
                     GATGIELAQEALTHHIGPVGNIFIAVCIFLFAFSSIVGNYYYGESNMEFMSGSKTKLN
                     VFRVFVVGMVLFGSLTQVDVVWNLADLFMALMAIINLIAIALLGKYAFIALKDYTSQK
                     KSGIKDPVFIADEIEGLEKVSEWHRELSEEHLG"
     gene            complement(4819..5460)
                     /locus_tag="OE968_003580"
     CDS             complement(4819..5460)
                     /locus_tag="OE968_003580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007491147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing protein"
                     /protein_id="HCP7220813.1"
                     /translation="MTDNYIFDSYNNLVDGLSAYLGEGYEFILYKFNGVHYSINKIAN
                     GKYNTVKEGDIITDFDLALINKLENDADGDFISYFNRNKLGEPLKSTDIVIRGVDNKI
                     IGLLCIHFYLNTPLTRIIGSYIPEHNAMQSAPVLENIVEDTDEVILKSYQDAKVIVEN
                     DSNISSNDKNKSIVSILNESGIFKIKDSVVKVADLMGLSKNTIYMHLRNLNKN"
BASE COUNT         2038 a          705 c          831 g         2026 t
ORIGIN      
        1 attaagagta ctataattta attaagtaat tacttaatca aaacgaggta cttatggaaa
       61 acttggttaa aatatttaaa gcattgagtg atgaaactag acttaacata cttatattag
      121 tatccaagag aaatatatgt caaaagggga tttctaaata tctagggatt tcagattctg
      181 ctgtttcaca acatataaaa atattaaaag atgttgggat aataacagga tataaagaag
      241 gatactatgt tttatatcat attaataaag aatcatttaa tatatgtgta gattttataa
      301 attctatgtt aagtaattct agtgaaagct ttatagatgt atttgatgta aatacaatac
      361 atctaggatg cagtaaagaa tgtaaatcta taaaaaaatg ttgtaagaga agggagaaat
      421 aataatgaaa gtatgtatac cagtagagga gaataaagga ttggatagta aaccatatgg
      481 acattttggt tctgctccaa tttttgttgt gtgtgattta gaaagtggag aagttaaatc
      541 tttagataat ggagatttag atcatgaaca tggaaaatgt caaccattaa aagcattgtc
      601 agggacagct gtagatgcag tagttgttgg aggaatagga caaggagcta taattaaatt
      661 aaatggaatg ggaataaaag tttacagagc agaaggtgat actataagtg ctaatttaga
      721 cttacttaaa aatggaaaat tagtagaatt tccatcagac catacttgct cacatgacgg
      781 atgtggacat cattaaaaaa aaacagctga tgaaatatat acttcatcag ctattttttc
      841 ttttaataaa tacgatttta ttcttttaaa accaaaattt agatttttat attttttgta
      901 gtatccttaa taatatttca agtttacaag tttactactt ttagattttt tttgtatgtt
      961 tttctatata gtcaatatca tttaatatgt cattgagttc tttattaagt gtttttaaat
     1021 catcaccatc tacattgtag tttaaaaata gttcctctac attatcaatg atagaattga
     1081 cttttctagt aacttcaaca aatgtcttaa agttactact atttttagca tttagaaatt
     1141 tttttaaatc ctttgatata aatgatacta tttcatattc atcattaaat agacctctac
     1201 caataggata tggttcaatt ctctgtaaaa aatattggtc tttagcatta atattataag
     1261 tataagatat ttcccaaccg tctcctaaat caaacttgat aaaatataat gtactactta
     1321 cttttgatat tcttgtggca ccaagctgtc ttaaaagaac ttcaatcgaa tcaccttgaa
     1381 cagtattaat attcatatat acacatcccc tttagtatta ttatactata ttttttaaaa
     1441 ttttataatt aaataaacag tagatataat aatagatata atcataagtg gaaaacctat
     1501 tttgaaatac tccttaaaag agataggatg accgtgttta ttacctatac ctgctagtac
     1561 aacattagca gatgctccta ttagtgttcc atttcctcca agacaagctc caagagatgt
     1621 tgcccaccat agtggcatta catcaatacc ttcagcttgc atagtcaaaa taagaggaat
     1681 tagtgttgca acaaatggaa tattatctaa gaaagaagag actatagctg acaaccataa
     1741 tatcaacaac attgtaaata caagatgtcc ttctgtaagt ccaatcaatg cttgagccaa
     1801 tttgtttatt atcccaactt ctactaatcc accaactact acaaataatc ccataaagaa
     1861 taaaattgta gaccattcaa tacctgccat aatttcatct acatcttgtt ttcctattaa
     1921 aagcattata gatgctcctg tcagtgctac aacagaagaa tctatgtgga ttgtactgtg
     1981 aaacataaaa ccaaaaagta tgaatgctat taatataagg ctttttataa gtagaggttt
     2041 atctttaaca gatttttttt catctagttt taatattgca tttttagctc tttcattcac
     2101 aacaagttct tttccataaa taaatctaaa gcatattata gttatagcaa gtattactat
     2161 aacagcagga cctaaattta ttacaaaatc cataaaacta agattggcag cactaccaat
     2221 cataatattt ggagggtctc ctataagagt agctgttcct cctatatttg aagctaaaat
     2281 ctgtgttatt aaaaatggaa ctggattaag tcctaatatt tgtgtaataa ctatagtcat
     2341 tggtccaata agtaagacgg ttgtaacatt atctaataca gctgataaaa tagctgttat
     2401 aatagcaaag caaatcatta tcttccatgg gtcaccctta gctttctttg cagtccagat
     2461 agctatatat tcaaataacc ccgagttttt gacaacagct acaaatagca tcataccaac
     2521 taatacacca atagtattga aatctatatg gcttaatcct tcatcaagtg taagtatatt
     2581 gaatattatc attaatagtg caccaccaac agctgctacg gatctgttta ccttttctgt
     2641 aataatagct gccataacta ttaaaaatat acatatagct attatttgtt gaaattccat
     2701 aatataagta cctccatttg tattattttg tgcctaatgc tagtactata tatagtatta
     2761 cttttttatt gttttttcaa tggatgtatg aaagtatatt atttaacaaa gtttttgaga
     2821 aattgacaga atttaaagaa aatttttgtt atttaaataa attttaaaat tattccattg
     2881 ataataatat taaacgacaa acgaaaaaat atacccttta aactagaatt tattgtatct
     2941 aataacaatt ataaaatatt aaatatatct atattataaa aacaataaaa aaaggtttga
     3001 tttgaatata aaactgcaat atattaaaaa aattattcat tttaaacctt gtaatttgat
     3061 tttataaata ttataattaa attaatgaat ttttaacaag gaattattca tttttttgat
     3121 tttaagattt attgagaaaa caaaactaaa taggggggta attaatataa tggatttttt
     3181 caatggtatt ttaacgagta ttaacaatgc agtagtattt gtaaacaatt acttatggtc
     3241 gtatatctta attataatgt tagttgtaat tggtatttac tttactatta aaacaaattt
     3301 tgtacaattc agatatttta tagaaatgtt tagacttctg ggtgatggta cagcgaataa
     3361 aaatgcaaaa aaggaaggaa aaatctcttc atttcaagca ttttgtataa gtacatcttc
     3421 aagagttgga actggaaata tagctggaat agcaattgca gtggtagcag gaggacctgg
     3481 tgctgtattt tggatgtggc ttatagcatt aattggttct gcatcaagct ttgttgagag
     3541 tacattagct cagatttaca aagtgaaaga tggtcaagct tttagaggtg gaccagcgta
     3601 ttatatggaa caaggtctaa ataaaaaatg gatgggtatt ttattctcaa tacttataac
     3661 tatatgttat ggttttgtat ttaatgcagt tcaagcaaat actgtttcac ttgcatttaa
     3721 taatgcattt ggaataagta aaatggctat gggaataggt cttggaattt taactgcaat
     3781 agttattttt ggtggagtgc atagagttgc aaaagtttct gaaataatag ttcctgtatt
     3841 tgcaggatta tatatattag ttgctttggc tatagttgta atgaatataa cagagatacc
     3901 aagtgttata gcattgatag ttgaaagtgc atttgatttt aaaggaatgg cgattggtac
     3961 atttatggga gttgtaatga ctggagtgaa gagaggtcta ttttctaatg aagcaggtat
     4021 gggtagtgct cctaatgctg ctgcaacagc acatgtaact catcctgtaa aacaaggttt
     4081 aattcaatct ttaggtgttt ttacagatac tataataata tgtagttgta cagcattcat
     4141 ggtattatta tattcaggtt atagtagtag tggagcaact ggaattgaat tagctcaaga
     4201 agctttaact catcatatag gaccagttgg aaatatattt atagcagttt gtatattctt
     4261 gtttgcattt agttctatag ttggtaatta ctattatggt gaatcaaata tggagtttat
     4321 gagtggaagt aagactaaac ttaatgtatt tagagttttt gttgtaggta tggttttatt
     4381 tggttcactt actcaagtgg atgtagtttg gaatcttgca gacttattta tggcattgat
     4441 ggcgataata aacttaatag caatagcact tttaggaaaa tatgcattta ttgctttaaa
     4501 agattataca agtcaaaaaa aatcaggaat aaaagaccct gtgtttattg cagatgaaat
     4561 agaaggccta gaaaaggtat cagagtggca tagggaatta tctgaggaac atttaggata
     4621 aaaaatagta taaaattata aaaccatttt gaaagactag agtatgtata tactttatat
     4681 gaatataata ttgaattaat ttatattact ggaattttta attccagtaa tattttttta
     4741 attacaagga tattatgatg acttaaagac tgtggaaaac tcttttttag ttttcattat
     4801 taatattaat tgacaaattt agtttttatt taaatttctt aagtgcatat aaatcgtatt
     4861 ttttgataat cccattaagt ctgcaacttt aacaacagaa tccttaattt taaaaatacc
     4921 actttcattt aaaatagaaa caatagattt atttttatca ttgctagata tattagaatc
     4981 attttcaaca attacctttg catcttggta tgattttaaa attacttcat cagtatcttc
     5041 tacgatattt tctaaaacag gagcactttg catagcatta tgttccggaa tatatgaacc
     5101 aattattctt gttagtggtg tattaagata aaaatgtatg cagagtagac cgattatttt
     5161 attatcaact ccccttatca ctatatctgt tgattttaaa ggttcaccta gtttgtttct
     5221 attaaaataa ctgataaaat ctccatcagc atcattttcg agtttattaa tgagtgccaa
     5281 atcaaaatca gttataatat ctccttcttt tacagtatta tatttaccat tagctatttt
     5341 atttattgaa tagtgtactc cattaaattt atataaaata aactcgtatc cttctcctaa
     5401 atacgcagat aatccatcca ctagattgtt ataagaatcg aaaatatagt tatcagtcat
     5461 gttaaaagtc atatgttacc tcctaagaaa tatcttaata tcatattaac atataaaatg
     5521 aatttaataa aatatatttc agtgaaataa taaatataat gaaaaaaaaa ctattgactg
     5581 aaaaatattt cagtgatatt
//
LOCUS       DAJMZY010000166         5584 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.171, whole genome shotgun sequence.
ACCESSION   DAJMZY010000166 DAJMZY010000000
VERSION     DAJMZY010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5584)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5584)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5584
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.171"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            198..704
                     /locus_tag="OE968_003581"
     CDS             198..704
                     /locus_tag="OE968_003581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase"
                     /protein_id="HCP7220814.1"
                     /translation="MGFREVKIEELQFNPFTKIGKEWLLITAGDSEKFNTMTASWGGV
                     GVYWGKNVVTTYIRPQRYTKEFVDSNDTFTIAFFDETYREALNICGTISGRDINKIEK
                     AGLTPYFVDDTVAFEEANMIIVCKKLYHGNMPPENFDAKENDKKWYPEKDYHTMYISE
                     IIKVLVKE"
     gene            1117..1785
                     /locus_tag="OE968_003582"
     CDS             1117..1785
                     /locus_tag="OE968_003582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220815.1"
                     /translation="MENITSYFTTILCVFICLSSVFIFTQLARVFINKKKINQKIKSR
                     NGFRYDRDFIEARREEIHIKDNNNNKNKSNNKKLKEEKVFKYDNGDLYKGEFVDGKKN
                     GFGIYIFSGKEKYEGLWKDDKMHGIGKYTYRDGSIYTGEFKYGLKNGLGKLTYPNNDI
                     YKGYFLDNKKNGKGVLYKNDGNKQAGIWEDDEQCKSLDFKDLNNNKINNVYQNRLNNN
                     KLKV"
     gene            1944..2450
                     /locus_tag="OE968_003583"
     CDS             1944..2450
                     /locus_tag="OE968_003583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HCP7220816.1"
                     /translation="MKEYVVVDLETTGLDPYKGCEIIEIGITEIKNEQIVKNYSRLIK
                     PKGIISSFITELTHISNEMVENEEPLELVLPRFRKYIGDRTIIAHNAKFDLKFLNYYL
                     RMLDLEPINNYICTVELLKKCKSYKGKNKKLETACAYYNIENINAHRADSDTLATAKL
                     FLKIKDEY"
     gene            2578..3594
                     /locus_tag="OE968_003584"
     CDS             2578..3594
                     /locus_tag="OE968_003584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase domain-containing protein"
                     /protein_id="HCP7220817.1"
                     /translation="MGYYNDNDNNKIRRKKISNNKDSNKKSKHSYTSANKKNKSPNTS
                     SSKRMSEKVDSQNLIKRDRDSFTRDNVRPLNTDYNQRERRRVEYKQREKKLKSKKRKK
                     QKRIRIVRALLSIMLVALIIFSVAGAIFTVSAIKGSPEVTKKLIRSKYISSEVVSIKQ
                     MPNDLKHAIVSIEDERFYKHKGVDVISLVRSVLNNVFTDTTQGASTIDMQVSKNLLTS
                     NDKTMKRKIRDMYNAKQMNKIMTKDEILEAYLNNMYLGKNAYGAAKGAEVYFGKKVSE
                     LNLAECAMLAGMTNNPARYIDHGEAKKRQVIVLYKMHQLGYITDKEYRIAKADDTPFK
                     SEID"
     gene            3948..4652
                     /locus_tag="OE968_003585"
     CDS             3948..4652
                     /locus_tag="OE968_003585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="B3/4 domain-containing protein"
                     /protein_id="HCP7220818.1"
                     /translation="MKKFVIEDAFWNLFPSAKIGVVICNDIDNSIKDEDYKKIILKGE
                     EEALKYLEDSEFSNNQVIKVWREAFKKFKTKKGARSSIEALLKRVHNGNNIGTINPLV
                     DIYNFISLKYALPCGGEDIDKFIGDIRLTRAIGNEEFIPLGTDENSFPYEGEIIYKDD
                     GGAICRCWNWREAVRTMLTEDTNNAFLCIELVDESRFKEFENALNELAKIVQEKLGGN
                     CKISILDIDNKEVSVD"
     gene            4947..5426
                     /locus_tag="OE968_003586"
     CDS             4947..5426
                     /locus_tag="OE968_003586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HCP7220819.1"
                     /translation="MSNKLIKNLLSGILQILFFLLGLVIVVGGFKSFMYLCFSGEATL
                     QGTIYGILMFILGVSYFIIIKSLIEVLGSSEYSLFVKENVKRFRIIGYLLLLNSLIEF
                     ISTFGTTGKGMRFLDLGFGFYFTVPVFVYFITSLMSFVIADGFVKAIKIKEDNDLTI"
BASE COUNT         2334 a          475 c          921 g         1854 t
ORIGIN      
        1 tttataatca atatatttta tctatatttt acacttataa aatatgaaaa ctacttattg
       61 cgaaagtaat tgatttgttg tattataatt tacatgaatt atgtaggaca atcaaaagtc
      121 agtattataa gagtacatat attcaaattt ttaacaatta atttatataa ttaaaaaatg
      181 aagggtagga tgaagtcatg ggttttagag aagtaaaaat tgaggaatta cagtttaatc
      241 catttactaa gattggcaaa gaatggttac ttataacagc tggtgattca gaaaagttta
      301 acacaatgac tgctagctgg ggtggtgttg gagtctattg gggtaaaaat gttgttacaa
      361 cttacataag accacagaga tatacaaaag aatttgtaga tagtaatgat acatttacaa
      421 ttgccttctt tgatgaaacg tatagagaag ctttaaatat ttgtggcact atttctggta
      481 gagatataaa taaaatagaa aaagcaggac ttacaccata ttttgtggat gatacggtag
      541 cttttgaaga agctaatatg attatagtat gtaaaaagct atatcatggt aatatgccac
      601 cagaaaactt tgatgctaaa gaaaatgata aaaaatggta tccagagaaa gactatcata
      661 ctatgtacat ttcagaaatt ataaaagttc ttgtaaaaga ataattataa taaaaaatat
      721 atgaaaagaa cttattataa gtaaatgact gtgctttctt atctgatatc taagtagatg
      781 ctactaacta aataaatatt aattttaaat aaatactatt ataaaaaaga tgaactatat
      841 ttactatagt tcatcttttt atttatataa gcacttatat aagtagagat ttatttgaat
      901 aaaagtattt atttgaaata tttgagtata ctttataagt atttttatgc taactagaaa
      961 cacttaattt atggcatttg tacttgattt attttaatgt aaataatttc aaagttaatt
     1021 ttattcaata tagtactata aaagtataaa taacatttaa taaaaatata tattatatta
     1081 ggtattttaa ataaattttt taaagggtga ttttttatgg aaaatataac tagttatttt
     1141 acaacaatac tatgtgtatt tatatgctta tcatctgtat ttatatttac tcaactagct
     1201 agagtattta ttaataagaa gaagattaat caaaaaatta aatcaagaaa cggatttagg
     1261 tatgatagag attttattga agccagaaga gaagaaatac atataaagga taacaataat
     1321 aataaaaata agagtaacaa taagaaatta aaggaagaaa aagtatttaa atacgataat
     1381 ggtgatttat ataaaggtga gtttgttgat ggaaagaaaa atggatttgg aatatatatt
     1441 ttttcaggta aggaaaagta tgaaggatta tggaaagatg acaagatgca tggaatagga
     1501 aaatatactt atagagatgg ttcaatatat acaggtgaat ttaaatacgg attaaaaaat
     1561 ggtttgggaa aattaacata tcccaataat gacatttata agggatattt tttagataat
     1621 aagaaaaatg gtaagggtgt attatataaa aatgatggaa ataaacaagc aggaatatgg
     1681 gaagatgatg aacaatgtaa aagtttagat tttaaagatt taaataataa taaaataaat
     1741 aatgtttatc aaaatagatt aaataacaat aaattaaaag tttaattatt ctaataaaaa
     1801 aatctttatt tatgatggaa tataggatat atctatgttg taatttgtaa aatcttccta
     1861 tatcatataa aattaagtat tgattagtct attacataaa tatagaatat aaatatatcc
     1921 atttaataat aaggagaaga gatatgaaag agtatgtagt tgtggattta gaaactacag
     1981 gattagatcc atataaaggt tgtgaaataa tagaaatagg aataacagaa ataaaaaatg
     2041 aacaaattgt aaaaaactat tcaaggttga taaaacctaa ggggataatt tcttcattta
     2101 taacagaatt gacacatata agtaatgaaa tggtagaaaa tgaagaacca ctagaattag
     2161 ttttacctag atttagaaaa tacataggtg atagaactat aattgcacac aatgcgaaat
     2221 ttgatttaaa atttttaaat tactatctta gaatgttaga tttagaacca ataaacaatt
     2281 atatatgtac agtagagtta ttaaaaaaat gtaaaagtta taaaggaaaa aacaagaaac
     2341 ttgaaacagc ttgtgcttat tacaacatag agaatataaa tgctcataga gctgacagtg
     2401 atacattagc aactgcaaaa ctatttttga aaataaaaga tgaatattaa ttataaatat
     2461 agagaaaatt agtgaaaata tcctttataa aattgaccct taagcttaca attttgttct
     2521 ttgatttatt ttgtagaaca atgtataatg taccttatat gaagaaggga gactaaaatg
     2581 ggttattaca atgataatga taataataaa ataagacgta aaaaaattag taacaacaaa
     2641 gatagtaata aaaaatctaa acattcttat acttcggcaa ataaaaaaaa taaaagtcct
     2701 aatacaagtt ccagtaaaag aatgagtgaa aaagtagatt cacagaatct tataaaaaga
     2761 gatagagata gttttacaag agataatgta agacctttaa atacagatta caatcaaaga
     2821 gaaagaagaa gagtcgagta taaacaaaga gagaaaaaat taaaaagtaa aaaaagaaaa
     2881 aaacaaaaaa ggattagaat agttagggca ttattatcta ttatgttagt tgcactaatt
     2941 atattttcag tggcaggtgc aatatttaca gtttcagcta taaaagggtc accagaagtt
     3001 actaaaaagt taattaggtc taaatatata agtagtgagg ttgtaagtat aaaacaaatg
     3061 ccaaatgatt taaaacatgc aatagtttcc atagaagatg agagatttta taagcataaa
     3121 ggagtagatg ttatttctct agttaggtca gtattaaaca atgtgtttac agatacaaca
     3181 caaggtgcaa gtactataga tatgcaagtt tcaaaaaacc tgcttactag taatgataaa
     3241 actatgaagc ggaaaataag ggatatgtat aatgctaagc agatgaataa gattatgact
     3301 aaggatgaaa ttcttgaagc atatttaaat aatatgtatc taggtaaaaa tgcatatgga
     3361 gctgcaaagg gagctgaagt ctactttggt aaaaaagtta gtgaattaaa tttagctgag
     3421 tgtgctatgt tagctggtat gacaaataat cctgcaaggt atattgacca tggagaggct
     3481 aagaagagac aagtgattgt actgtataag atgcatcagc ttggttatat aactgataag
     3541 gagtatagaa tagcaaaagc tgatgacact ccatttaaat cagaaattga ttaaaattgt
     3601 aagaatatag tattttcaat agtttaaaca aacaaaaatg taataaaaaa ggtgatttgc
     3661 cacccatttg ccaccataat tataatctaa tggcaaattg ttttaatgta caaactagat
     3721 aatagaatat tgtcttaaat gctatattat gctaaaattt aattgtattt tgtaaattaa
     3781 aaaacttata atttagtttt ctagggttcc gcattttata atggtcaggt ccaagagaaa
     3841 acgcgcaatt gttgtgtaca cggaaggata aaagcctggg agatatttaa gaatatttct
     3901 ataggctttt ttatttttac atattttaaa tttgaggagg ttttctaatg aaaaaatttg
     3961 ttattgagga tgcattttgg aatctatttc ctagtgcaaa aattggagtt gttatttgta
     4021 atgatataga taactctata aaagatgaag actataagaa aataattttg aagggagaag
     4081 aagaagcatt aaaatacttg gaggactcag aatttagcaa caaccaagtg attaaagtat
     4141 ggagagaagc atttaaaaaa tttaaaacga aaaaaggagc aaggtcttct attgaagcat
     4201 tattaaaaag agttcataat ggaaataata taggaactat taacccttta gtggatatct
     4261 acaattttat ctcattaaaa tatgcattac cttgtggagg ggaggatata gataaattta
     4321 taggagatat taggctaact agagcaattg gtaatgagga gtttatccca ctagggacag
     4381 atgaaaattc atttccatat gaaggagaaa taatttataa agatgatggt ggagcaattt
     4441 gtagatgttg gaattggcgt gaagcagtga gaacaatgct tactgaagat actaacaatg
     4501 cctttttatg cattgaatta gtagatgaaa gtagatttaa agaatttgaa aatgctttaa
     4561 atgaattagc taaaatagtt caagaaaaat tgggtgggaa ttgtaaaatt tcaattttag
     4621 atattgataa taaagaggta tcagtggatt aatatggagg tgctgttgta atggactatt
     4681 ctagttataa agatacttat atttagggta agaaggtcta ttttagatat aacgattatc
     4741 aaaggatata atatagaaaa taaaaatgta gaatataaaa agcctttaaa ataagaaaaa
     4801 aatgtatttt aaaggctttt attatactct tttttatttg cataattaac aataaaaata
     4861 tattgttaat tataatattt ttatttaaaa acgatataat ataatgtatt atactatata
     4921 taaaatattt taaaggagtt ggcatgatgt ctaataaact tataaaaaat ttactaagtg
     4981 gtatattaca aattttattt tttcttttag gattagtaat tgttgtagga ggatttaaaa
     5041 gttttatgta cctctgtttt agtggagaag caactctaca aggtactatt tatggaatat
     5101 taatgtttat tttaggtgta tcatatttta tcattataaa atcattgata gaagtattag
     5161 gtagttctga atatagccta tttgtaaaag agaatgtaaa aagatttagg attattggat
     5221 atcttttgct tttaaactct ctaattgagt ttatttcaac ttttggtact actggaaaag
     5281 gaatgagatt tctagattta ggatttggat tttattttac tgttccagta tttgtatatt
     5341 ttataacttc tctgatgagt tttgtaattg cagatggatt tgtaaaggca ataaagataa
     5401 aagaggataa tgatttaact atttaggtgt gacactttaa tatataggag ataaataacc
     5461 cgaaaagagt gactaactag taatttaaaa taaaatatat tagggtataa tacataaact
     5521 ataatgctaa aattaaaaga ttataatact aaaatataat tatgttttaa ttaaaataaa
     5581 gaac
//
LOCUS       DAJMZY010000167         5525 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.172, whole genome shotgun sequence.
ACCESSION   DAJMZY010000167 DAJMZY010000000
VERSION     DAJMZY010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5525)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5525)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5525
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.172"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            50..166
                     /gene="rrf"
                     /locus_tag="OE968_003587"
     rRNA            50..166
                     /gene="rrf"
                     /locus_tag="OE968_003587"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            complement(380..1564)
                     /locus_tag="OE968_003588"
     CDS             complement(380..1564)
                     /locus_tag="OE968_003588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HCP7220820.1"
                     /translation="MLSKRLNFITPSYTIGISSKVKEMESNGVKVINLSIGEPDFNVP
                     NNAKSYGIDSLNKDYTKYDLVPGLKILREEICKKLIEENNCNYSIDEIVVSSGAKNSI
                     TNTLLALTDEGDEVLLPKPYWVSYPEMIKLVNAVPVFIDTKKENGFKLTKEELEKSIT
                     DKTKILVINNPSNPTGSVYTKDELIEIVDVCIQNKIYILADEIYEKICYTGEFTSIAS
                     LSEEAKDITITINGFSKSAAMTGLRLGYTASNKTIAKAMSSIQGHLISHPSLTAQYIA
                     YGALKDCSIDIDNMVKTYKSRRDLIKSKLDSIDNVGYVNPNGAFYIFIDLSKVSEKFE
                     YKDSFSIEFCNQFLEEYNVAVVPGIAFGMDKYIRISYACSENTFLSGLDKLKEFVYKI
                     MA"
     gene            1937..4288
                     /locus_tag="OE968_003589"
     CDS             1937..4288
                     /locus_tag="OE968_003589"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside triphosphate reductase"
                     /protein_id="HCP7220821.1"
                     /translation="MVEFVKKRDGRVIPFNEDRITRAIFLAATNVAEREGIVPDYKLS
                     EQLTQEVIKFLNHKYSESVPSVEDIQDSVVKVLIETGHAKTSEEYIIYRTERSRIRNS
                     KTRLMKAIEEITFEDAEDADIKRENANINGNTAMGTMLQYGSTVSKEFCKTHILKPEH
                     SFAHDNGDIHIHDMDFLNMGTLTCCQIDVKKLFNGGFSTGHGFLREPQDIISYGALAA
                     IAIQSNQNDQHGGQSIPFFDYGLAEGVYKTFKKFYIGNLAKALKLFKGIENNDVIKNI
                     VYNTEKETNQKVGLKRDELYLNLEKEKLIQTFDIDDELVNKMQNFAFEESYRETDKKT
                     YQSMEAFIHNLNTMHSRAGAQVPFSSVNFGTDTSEEGRMVTKNLLLSQERGLGNGETP
                     IFPILIFKVKEGINLNPEDPNYDLFKLSCRVSAKRLFPNFSFLDAPFNAKYYKKGEPD
                     TEATYMGCRTRVLSNVCGSETVSGRGNISFTTVNLPRLGIKHGIINNEKANLDGFFEE
                     LDEKINLIIEQLLERLEVQGNKKMKNFPFLMGQGVWKGSDDLGPEDTLKEVIKQGTLT
                     IGFIGLAECLIALIGKHHGESKEAQELGLKIVSHMRHKMDEATDKYKLNFSLMGTPAE
                     GLSGRFTKIDKKVYGEIKGITDKEYYTNSFHVPVYYNISAYDKIEIEAPYHELTNAGH
                     ITYVELDGDPSDNLEAFETVIKAMKDLGIGYGSINHPVDRDPICGFSGVITSNICPVC
                     GRNEDESDIKFERIRRITGYLVGTVDRFNNAKKAEVRDRVKHR"
     gene            4310..4849
                     /gene="nrdG"
                     /locus_tag="OE968_003590"
     CDS             4310..4849
                     /gene="nrdG"
                     /locus_tag="OE968_003590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HCP7220822.1"
                     /translation="MKIRMSSTISYDSIVDGPGLRMVIWTQGCIHNCKECHNPQTHDL
                     CGGFYMDTEEIINKVKSLKLQKGITLSGGEPFLQPEPLEEIAKEAKINGLDVWSYTGF
                     TFEQLLDKKNRAYFKNLNLLKQIDILVDGKFIAEKKDISLKFRGSSNQRIIDVQKSLK
                     YKQVFLVEQYMKDDLSIAE"
BASE COUNT         2151 a          625 c          888 g         1861 t
ORIGIN      
        1 ttctataaac ttattaaaaa cttaatagaa atattaagca taaagattat gtggttacaa
       61 tagcagagag gatacacctg ttcccattcc gaacacagaa gttaagctct ctagcgctga
      121 tggtacttgg tgggaaactg cctgggagag taggacgtag ccacgtaatt tttttgttat
      181 aataaattta gaatttaact tatatagttt aatttgataa tttgatgaaa aaaataaaag
      241 acttattgat ttttaaatct ataggtcttt tattttttat ctaacattta aattaagttg
      301 ttgaatatat cttatattac ttaccttata tattaattat cattaataca ttatatctaa
      361 ttactattca tctaaattat tatgccatta ttttatatac aaattctttt aatttatcta
      421 atccagataa gaaagtattt tcactgcaag cataggatat acgaatatat ttatccatac
      481 caaatgctat gccaggaaca actgcaacat tatattcttc taaaaattga ttacaaaatt
      541 ctatagaaaa actatcttta tattcaaatt tctcagatac tttagaaaga tctataaata
      601 tatagaatgc gccatttgga ttcacatatc ctacattatc aatagagtct agttttgatt
      661 taattaaatc tcttcttgat ttatatgttt taaccatatt gtctatgtca attgagcaat
      721 ctttcaaggc tccataggct atgtattgtg ctgttagact tgggtgagat ataagatgtc
      781 cttgtataga actcattgct ttagcaatcg ttttattaga tgcagtatat cctaatctta
      841 atccagtcat tgcagctgac ttagaaaaac catttatagt tattgttata tctttagctt
      901 cttcgcttaa tgatgcaatt gatgtaaatt caccagtgta gcatattttt tcatatattt
      961 catctgctaa aatatatatt ttattttgta tgcatacatc tactatttct attaattcat
     1021 cttttgtata aacactacca gtaggatttg aaggattgtt tattacaaga atttttgttt
     1081 tatctgttat agatttttca agttcttctt ttgttaactt aaatccattt tcttttttag
     1141 tatcaataaa aactggaaca gcattaacta acttaatcat ttcaggataa ctaacccaat
     1201 aaggctttgg taataagact tcatctcctt cgtctgttaa agctagtaaa gtatttgtta
     1261 ttgagttttt tgctccactt gatacaacta tttcgtctat tgaatagtta cagttatttt
     1321 cttcaataag ttttttacag atttcctctc taagtatttt taatcctgga actaaatcat
     1381 atttagtgta atctttattt aaagaatcaa taccataaga ttttgcgtta ttaggtacat
     1441 taaaatcggg ttctcctata ctaagattta ttactttaac tccattactt tccatttctt
     1501 taactttaga actaatacct attgtgtagg atggtgttat aaagtttagt ctttttgata
     1561 acataaaatg cctcctttta aattattatt tatattatac gacaaattta aagaatttac
     1621 ataaggaaat ttgtagatat atacattaat atatataata gcctacactt tttgcctaaa
     1681 attagtgtaa aaaaaagaga aaaaaatttt aactttcaaa gttgttagaa acgctactgt
     1741 tcaaaatatc cacatagtat ttgcaatgat ttgcgcaagt ttgactatta tgtacaaatt
     1801 tggtaatctt aatatagcaa ttattaagat aatcccttta acttagttga aggggatttt
     1861 tttagactta acatactaca tatagtggta tggggattaa taaaatacaa tatatagtaa
     1921 caggaggttt ttttaattgg ttgaattcgt aaaaaaaaga gatggaagag taattccatt
     1981 taatgaagat agaataacaa gagctatatt tttagcagca acgaatgttg cagaaagaga
     2041 aggaatagta cctgattata aattatctga gcaattaact caagaagtaa taaagttttt
     2101 aaatcataaa tactcagaat cagttccaag tgttgaagat atacaagatt ctgtagttaa
     2161 ggttcttata gaaactggcc atgcaaaaac tagtgaagaa tatataatat acagaactga
     2221 aagaagtaga ataagaaatt caaaaacaag gttgatgaag gcaatagagg aaattacctt
     2281 tgaagatgca gaagatgctg atataaaaag agaaaatgca aatattaatg gtaatacagc
     2341 aatgggaact atgttacaat atggaagcac tgtatctaaa gaattttgta aaacacatat
     2401 attaaaacca gagcattctt ttgctcatga taatggagat atacacatac atgatatgga
     2461 ttttttaaat atgggaacat taacttgttg tcaaatagat gttaaaaaac tattcaatgg
     2521 tggattttca acaggacatg gctttttaag agagccacaa gatataataa gttatggtgc
     2581 attagctgca attgctatac aaagcaatca aaacgatcaa catggaggtc aaagtatacc
     2641 atttttcgat tatggattgg ctgaaggtgt atataagaca tttaagaaat tctacatagg
     2701 aaatttagct aaagcattaa agttatttaa aggaattgaa aataatgatg tgataaagaa
     2761 catagtatat aatacagaga aagaaacaaa tcaaaaagtt ggtcttaaga gagatgaatt
     2821 gtatctaaac ttagaaaaag agaaattaat acagactttt gatatagatg atgaacttgt
     2881 aaataagatg caaaactttg catttgaaga atcgtataga gaaactgata aaaaaacata
     2941 tcaatctatg gaagcattta tacacaatct aaacacaatg cactctagag caggtgcaca
     3001 ggtaccattt tcaagtgtaa acttcggaac agatacttct gaagaaggaa gaatggtaac
     3061 taagaatctt ctattatctc aagaaagagg tttaggtaat ggagagacac caatttttcc
     3121 aattttaata tttaaggtca aagaaggcat aaatttaaat cctgaagacc ctaattatga
     3181 tttatttaaa ttatcatgca gagtatcagc taaaagacta ttccctaatt ttagtttttt
     3241 agatgcgcct tttaatgcaa aatattataa aaaaggtgaa ccagatacag aagctacata
     3301 tatgggttgt agaacaagag tacttagtaa tgtgtgtggt tcagaaacag ttagtggtag
     3361 aggaaacata tcttttacta cagtaaattt accaagattg ggtataaaac atggtattat
     3421 aaataatgaa aaggctaatt tagacggttt ctttgaagaa ttagatgaga agataaactt
     3481 aattatagaa caattattgg agcgccttga ggtacaagga aataaaaaga tgaagaattt
     3541 tccattctta atggggcaag gtgtatggaa aggttctgat gatttaggac cagaagatac
     3601 actaaaagaa gtaataaaac aaggaacatt gacaattgga tttataggtt tagcagagtg
     3661 ccttattgct cttataggta aacatcatgg agaaagtaaa gaagctcaag aattaggatt
     3721 aaaaatagtg tcacatatga gacataaaat ggatgaagca acggacaaat ataaattaaa
     3781 tttctcctta atgggtactc cagcagaagg tctttcaggt aggtttacta aaatagataa
     3841 aaaagtttat ggagaaatta aaggtatcac agataaagaa tattatacta attcattcca
     3901 tgtaccagtt tattacaata taagtgcata tgataaaatt gagatagaag ctccatacca
     3961 tgaattgact aatgcaggtc atataacata tgtagagtta gatggagatc catctgataa
     4021 tttagaagct tttgaaactg ttataaaagc tatgaaagat ttgggtatag gatatggaag
     4081 tataaatcat cctgtagata gagacccaat atgcggtttt tcaggtgtaa taacaagtaa
     4141 tatatgccct gtatgtggaa gaaatgaaga tgaaagtgat atcaaattcg aaagaataag
     4201 aagaataaca ggatatttag ttggtacagt tgatagattt aataatgcta aaaaagcaga
     4261 agtaagagat agagtaaaac atagatagtt ttatttgggg gaataagtta tgaaaataag
     4321 aatgtcatct actataagtt atgacagcat agttgatgga ccaggattaa gaatggtaat
     4381 atggacccaa ggatgtattc ataattgtaa agagtgccat aatcctcaga cacatgattt
     4441 atgtggagga ttttatatgg atacagaaga aattataaat aaagtcaaat cattgaaatt
     4501 acaaaaaggc attacgctat caggaggaga accattttta caaccagaac cattagaaga
     4561 aatagcaaaa gaagctaaaa taaatgggtt agatgtatgg tcatatactg gatttacgtt
     4621 tgaacaactg ttagataaaa aaaatagagc gtattttaaa aatttaaatt tactaaagca
     4681 aattgatatt ttagtggatg gaaaatttat agctgaaaaa aaagatataa gcttaaagtt
     4741 tagagggtca tcaaatcaaa ggataattga tgttcaaaaa agtttgaaat ataaacaagt
     4801 gtttttggtt gagcaatata tgaaggatga tttatctata gcagaataaa atataaataa
     4861 acaggattaa atatatgcat atatttaatc ctgtttattt tcatataata tttcaagctt
     4921 gtataatgta acaattaaac caaaagactc attgtatatt tgaaattaag ttttttatag
     4981 tttataggtg ttttatgtgg attacgaatg atatagtatt gatacattat ttaatagatt
     5041 cttatgccaa gaaacaatta atttatagaa attcttaatt gttacaatat aaatatctag
     5101 atatgttata agatactgat aaataattta taaagtttat taatctaata ttgtgtgtga
     5161 atattaagtg gtcaagtagt ctaaaaaatg aaaaagattt aaaaaagtgt tttaactaaa
     5221 cacataagtg ttaaattcat gtataagtat aggttagata cataagaaat aattatgtaa
     5281 tatctatctt tgtaaaaaaa tattaaattt tgtaatttgt ggataaatat gtttataatg
     5341 tggataatat ttaatgtaat aagttaaagc aatatgaatc aactgtttat aatgtggata
     5401 atattataaa tgtatgaata attgcagtat ttaaaaacaa aaaaagttaa aaaagttgtt
     5461 gactctaaaa gaaaaagttg gtatagtaat acttgtcctc aagaaaaggg caaacaaata
     5521 aagca
//
LOCUS       DAJMZY010000168         5485 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.173, whole genome shotgun sequence.
ACCESSION   DAJMZY010000168 DAJMZY010000000
VERSION     DAJMZY010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5485)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5485)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5485
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.173"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            <1..967
                     /locus_tag="OE968_003591"
     CDS             <1..967
                     /locus_tag="OE968_003591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HCP7220823.1"
                     /translation="SNDKVFEEFLYKHISSLCKKIKLGINQSPIMAQDIKIKYPFAFE
                     LANIAKKTIEKDLKIEINEDEVANIALHIGGAVERASYNNKDKVFKTIIVCTSGIGTS
                     MLIKAKLENIFKEKLEILKIIPSYLVEYIKVIDVDFVISTVPIEVGDVPVINISPILS
                     EKEIRLIEKYIETGNIYLDLDIKSLFDSELFFTDLVFKRKEEVIDFMASKLVQKGYID
                     EDMKKSYFEREKIATTEIGNMVTIPHGAIGKIFDNKIAIGILKKPISWEISDVRLIIM
                     LALDKDKILDYEVIFSKIYKRVDSIAKVISICENSSFEKFVNLFN"
     gene            1134..2051
                     /gene="pfkB"
                     /locus_tag="OE968_003592"
     CDS             1134..2051
                     /gene="pfkB"
                     /locus_tag="OE968_003592"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HCP7220824.1"
                     /translation="MIYTVTLNPSIDYIVKLDELKTGSTNRVKEEYVYPGGKGINVSR
                     ILKELGNDNTSLGFISGFTGEYIIRTLEEKELKTDFIKIKSGFSRINVKIKALKETEI
                     NGQGPNIDDEDIDTLYKKLDKLNQDDILILAGSIPSTLDEKLYENIMARLEKKNIKVV
                     VDATKNLLLNVLKYKPFLIKPNNDELEELFGVKLNSIEDMVKYARRLKEMGAINVLVS
                     MGKDGALLITEEDEVLISDVPKGKVKNSVGAGDSMVAGFISGYLNTGKYDYALKLGAA
                     SGSATAFSYDLAKREYIDKLVNEISVKKF"
     gene            2088..4007
                     /locus_tag="OE968_003593"
     CDS             2088..4007
                     /locus_tag="OE968_003593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HCP7220825.1"
                     /translation="MKIIDLLDEKSIKLNLNSKTKSEAIEELVDLVANSGNLNDKENY
                     KKAILAREEMSTTGIGEGVAIPHAKNSSVTKACIAAAVSKEGIDYESFDGSLSNLFFM
                     IAAPDGANNTHLEVLSRLSTILMDEDFRNKLINSSSEKEFKEIIDKKEREKFSEEYQD
                     EKVAEKNIIDTKENDANKYPKVLAVTACPTGIAHTFMAAESLNKMAENKGVSIKVETN
                     GSAGVKNKLTKDEIENATCIIVAADKNVEMARFNGKKVIKTKVADGIHKAEELIDKAV
                     NGDAPIYHGGDGSHNESNEESESGFRKVYKHLMNGVSNMLPFVIGGGILIAIAFLLDD
                     YTINPSNFGSNTPIAAFFKGIGDKAFGFMLPVLAGYIAYSISDRPAFVVGFVGGALAG
                     DGGSGFLGALLAGFIAGYLVEGLKKIFSVLPASLEGIKPVLLYPLLGTLLMGIIMTFL
                     VIPPVTAINNAMVGFLNGLGGTSKIVLGLVLGGMMAVDMGGPVNKAAYVFGVASLESG
                     QFEIMAAVMAGGMVPPLAIALATTFFKNRFTKEERDSGKVNYVMGLSFVTEGAIPFAA
                     GDPLHVIPACVGGSAVAGALSMLFNAALRAPHGGVFVIPVVTHPFAYILAIAVGALVG
                     MMLLALLKKPLNQEV"
     gene            4503..>5485
                     /locus_tag="OE968_003594"
     CDS             4503..>5485
                     /locus_tag="OE968_003594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HCP7220826.1"
                     /translation="MIFTIIFYKKGRLCLLNLQSKWVNFLKPTYVSDEIKRKKLQVII
                     FFSITYGLSYSLGLLAICFNHLIDSEILAQFMMILPLSSVSIAKFYTEGRNNDKYNFY
                     SSVILFFIIYFFIFIIESLKLISINQFQLMYLMLILISSLCVIVYSYKITSLYIFKNF
                     KIGILLFFYFLFSQIIFGLIISDNQFDYKNFLNYILLPIISLVYIYPFLCEEYGWRSF
                     LQSILFDRFGKKIGIVMVGTCWSLWHLPLQFTLYSPQTPIIGAIANLIYGIGLSIFLG
                     YVYMKTKNIWFCSIMHVLINSLGLIFNDSEIIINYHSIIQRLIFILLFYTP"
BASE COUNT         2127 a          535 c          958 g         1865 t
ORIGIN      
        1 aagtaatgat aaggtatttg aagagttttt atataagcat attagtagtt tatgtaaaaa
       61 aataaagtta ggtataaatc aatcacctat aatggctcaa gatataaaaa taaaatatcc
      121 atttgctttt gaactagcta atatagctaa aaagacaata gaaaaagatt tgaagataga
      181 aattaatgaa gatgaagttg caaacatagc tctacatata ggaggagcag ttgaaagagc
      241 atcttataat aataaagata aggttttcaa aactataata gtttgtactt caggcatagg
      301 cacatcaatg ttaataaaag ctaaattaga gaatatattt aaggaaaaat tagaaatact
      361 aaagattatt ccttcatact tagttgaata tataaaagtt atagatgttg attttgtaat
      421 atctactgtt cctattgaag taggagatgt gccagtaata aatatatctc caattttaag
      481 tgagaaagaa attagattaa ttgaaaaata tatagaaaca ggaaatatat acctagattt
      541 agatataaaa agcctgtttg atagtgaatt gttttttact gatttggtgt ttaaaaggaa
      601 agaagaagtt atagatttta tggcaagtaa acttgtacaa aagggctata tagatgagga
      661 tatgaaaaaa tcttactttg agagagaaaa aatagcaaca acagaaatag ggaatatggt
      721 aactatacca catggagcta ttggaaaaat ttttgataat aaaatagcaa ttggtatatt
      781 aaagaagcct atttcttggg aaatatcaga tgttcgttta ataataatgt tagcccttga
      841 taaagataaa atattagatt atgaagtaat attttcaaaa atatataaaa gagtagattc
      901 tatagcaaaa gttataagta tatgtgaaaa tagtagtttt gaaaaatttg taaatttatt
      961 taattagatg ggtagtattg tatatacacc tgtaaatttg gataatataa aactaaataa
     1021 gataaaaacg ataaatttct cttttaatta agagaaattt tttgactttc aaggatatta
     1081 atataaagtt aagatataaa cataaagcaa ataaataaaa aagaggtggc aatatgattt
     1141 atacagtgac attaaatcca tcaatagatt atatagttaa gctagatgag ctaaagacag
     1201 gaagtacaaa tcgtgtaaaa gaagaatacg tttatccagg aggaaaaggt ataaatgtat
     1261 ctcgcatact taaggaactt ggaaatgata atacatcttt aggttttata agtggtttta
     1321 ctggagaata tataataaga acattggaag aaaaagaatt gaagacagat tttataaaga
     1381 taaaaagtgg tttttcaaga ataaatgtaa aaataaaggc gttaaaggaa actgagatta
     1441 atggacaagg tccaaatata gatgatgaag acattgatac tttatataaa aaacttgata
     1501 agctaaatca agatgatatt ttaatattgg caggaagtat accatctact ttagatgaaa
     1561 aactatacga aaatataatg gctagattag aaaaaaagaa tataaaagtt gtagtagatg
     1621 caactaaaaa tcttcttctt aatgttttaa aatacaaacc ttttctaatt aagcctaata
     1681 acgacgaatt agaagaacta tttggtgtta aattaaattc aattgaagac atggtaaaat
     1741 atgctagaag gttaaaggaa atgggagcta taaatgtctt ggtatcaatg ggaaaagatg
     1801 gagcattgtt gattacagag gaagatgaag tgcttataag tgatgttcca aaaggaaaag
     1861 taaaaaattc tgtaggagca ggtgattcaa tggtagcagg atttatatct gggtatttga
     1921 atactgggaa atatgattat gctcttaaat tgggagcagc ttcaggtagt gcaactgctt
     1981 tttcatatga cttagccaaa agagaataca ttgataaatt ggtaaatgaa atatctgtaa
     2041 agaagtttta aaatattaaa aaatatatag aaaggtaatt aatatttatg aaaattatag
     2101 atttattaga tgaaaagtca attaagttaa atttaaattc aaaaaccaaa tcagaagcaa
     2161 tagaagaatt agtagatttg gtcgcaaata gtggaaattt aaatgataaa gaaaactaca
     2221 aaaaagcaat tttggctcgt gaagaaatga gtacaacagg aattggagaa ggtgtagcta
     2281 tacctcatgc taaaaattct tcagttacta aagcttgtat agcagcagca gtgtcaaaag
     2341 aaggtataga ttatgaatcg tttgacggaa gtttatcaaa tctatttttt atgatagctg
     2401 caccagacgg agctaacaat actcatcttg aagtattatc aagattatct acaatactta
     2461 tggatgaaga ctttagaaat aaacttataa attcaagctc tgaaaaagaa tttaaggaaa
     2521 taatagataa aaaggaaaga gaaaaattca gtgaagaata tcaagatgag aaagtggctg
     2581 aaaaaaatat aatagatact aaagagaatg atgctaataa gtatcctaag gttttagcag
     2641 taacagcatg tccaactgga atagcacata catttatggc agctgaaagt ttaaataaaa
     2701 tggcagaaaa caaaggtgta tcaataaaag tagaaactaa tggttcagca ggtgttaaaa
     2761 ataagcttac aaaagatgaa atagaaaatg caacatgtat aatagtggca gcagataaaa
     2821 atgttgagat ggctagattt aatggcaaaa aagtcataaa aactaaggtg gctgatggta
     2881 tacacaaagc ggaagaactt atagacaagg ctgtaaatgg agatgctcca atttaccatg
     2941 gaggagatgg aagtcacaac gaatcaaatg aagaaagtga aagtggattt agaaaagtat
     3001 acaaacactt aatgaatggt gtatctaata tgttaccatt tgttattggt ggagggatac
     3061 ttatagcgat agccttttta cttgatgatt atactattaa cccttcaaac tttggttcaa
     3121 atacacctat agcagcattt tttaaaggaa taggagataa agcttttgga tttatgttac
     3181 ctgtacttgc tggatatata gcatactcta tatctgatag accagcgttt gttgtaggat
     3241 ttgtaggagg tgctctagca ggtgatggtg gttcaggctt tttaggtgca ctacttgcag
     3301 gttttatagc aggttattta gtagaagggc ttaagaaaat atttagtgta ctaccagctt
     3361 cattggaagg aataaaacca gtattgttat atcctttact tggaacactt ttgatgggaa
     3421 ttataatgac atttttagta atacctccag ttacagcaat taataatgca atggttggat
     3481 ttttaaatgg tttaggtgga acttcaaaaa tagttttagg attagtatta ggtggaatga
     3541 tggctgtgga tatgggtgga cctgtaaata aagcagcata tgtatttgga gttgcatcac
     3601 ttgaatcagg gcagtttgaa ataatggcag cagtaatggc tggtggtatg gttccgccac
     3661 ttgctatagc tcttgcaact acatttttta agaatagatt tactaaagaa gaaagagatt
     3721 ctggtaaagt taattatgta atgggattat catttgttac tgaaggagct ataccttttg
     3781 cagctggaga cccacttcat gttataccag cttgtgttgg aggttcagca gtggcaggag
     3841 cacttagtat gttgttcaac gcagctcttc gtgcacctca tggaggagta tttgttatac
     3901 cagtggttac ccatccattt gcatatatat tagctatagc tgtaggtgct ttggttggaa
     3961 tgatgctttt agcattactt aaaaaaccat taaatcaaga agtatagcaa ttaaaggata
     4021 ttcaagaact taaaatatga tgttttataa aaattaatat attgctgaat tattttaaaa
     4081 taaggatttt atgaggctgt tatataacga tttgtaattg ttatcttgac agtcttttat
     4141 ttttatataa gtaaaataag tgtgttttgc tttatttgta tttaaattgt ttttaagtta
     4201 gaatataaag aaaattatat attattttaa tattcactcg aactagaaaa taatatttgt
     4261 tgtatttttt gtatataaaa atatattgta atattaaaaa aataatagta aactgattgc
     4321 ataaaaatga tttttatata aattttaaac agaagaataa atttctaacg aaattggata
     4381 tttcttctgt aaatacatat tcaaaaaaag aattataaga gtttagtcag cagtcgtgta
     4441 agtaataagg actttataaa tatatagaaa tataatgata tgagtataag tagaaaaatt
     4501 ttatgatttt tacaattatt ttttataaaa aagggaggtt atgtttgttg aatttacaat
     4561 caaaatgggt aaacttttta aagccaacat atgtcagtga tgaaataaaa agaaaaaaac
     4621 tacaagttat aatatttttt tctataactt atggtttatc ttattcacta ggtttattag
     4681 caatatgttt taatcattta atagattcag aaattttagc tcaatttatg atgatattgc
     4741 cattatcttc agtttctatt gcaaaatttt acacagaggg aagaaataat gataaatata
     4801 atttctattc atcagtaata ttatttttta ttatttactt ttttatattt attattgaat
     4861 cattaaagtt aataagtatt aatcaatttc aattaatgta tcttatgtta attttaataa
     4921 gtagtttatg tgttattgtt tattcttata aaataacaag tttatatatt tttaaaaatt
     4981 ttaagatagg tattttgcta tttttttact ttttgttttc tcaaattatt tttggattaa
     5041 taataagtga taatcaattt gattataaga atttcttgaa ttatattctt cttcctataa
     5101 tatcattagt atacatttat ccttttttat gtgaagagta tggttggaga tcttttttgc
     5161 aaagtatttt atttgataga tttggcaaaa aaatagggat tgtaatggta ggcacttgtt
     5221 ggagtttatg gcacttacct ttacaattta cactatatag tcctcaaact ccaataattg
     5281 gagctatagc caatttgata tatggtattg gactttctat atttttaggt tatgtttata
     5341 tgaaaactaa gaacatatgg ttttgctcta taatgcatgt tctaattaat agcttaggat
     5401 taatttttaa tgattctgaa ataattatta attaccatag tattatacaa agattgatat
     5461 ttatactatt attttatact ccttt
//
LOCUS       DAJMZY010000169         5450 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.174, whole genome shotgun sequence.
ACCESSION   DAJMZY010000169 DAJMZY010000000
VERSION     DAJMZY010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5450)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5450)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5450
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.174"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            complement(1005..2084)
                     /locus_tag="OE968_003595"
     CDS             complement(1005..2084)
                     /locus_tag="OE968_003595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HCP7220827.1"
                     /translation="MILITLCILVAVFVLAFAGLRLIAPTIIRTSHKIEAPGIDRMEM
                     VEIGGIQQALYIRGQNADNPIILWVHGGPGNSMMPFLHLYQYEWENDFTVVNWDQRNV
                     GKTYFANDPAAVLQTMSAERVLQDVHEVTAYLKQEFNKEKIILIGHSWGTVLGTMAVQ
                     TYPEDYSAYIGIAQTVNMVDNERVGYEKTLEMVKAAGKQKDIKALEAIAPYPPAKYGP
                     SYLAALMTVRTYQSKYGLSINMDLGNIISILATPYYSLRELKNTAIVNPNAIDNQGDV
                     LRFLVEEADIRNYGVDYQVPVYYIMGENDYNSPYLPAKKFFDEIVAPDKQIFFIPDAD
                     HLPFLSKKAEFDCVLLEEIAPKLAK"
     gene            complement(2168..2824)
                     /locus_tag="OE968_003596"
     CDS             complement(2168..2824)
                     /locus_tag="OE968_003596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCP7220828.1"
                     /translation="MTRKNNPKQAIENIITISAKLFAEKGYDKTSMQNIVDASGMSKG
                     GIFHHFSSKEDIFNVVMERRFEQIIETVNQWLGEMHGLTAKEKLRSLVRRHLTDEVIK
                     ESSNMITSAIESPHIILAFTQDNLKKLAPILANVLREGIEDRSIITEFPDECAEVILL
                     LFNFWCDTDVFQGDFPTLRKRFQFLQFLMRQIGVDILEDEIIESINIFYERKPMGQVE
                     "
     gene            3146..3352
                     /locus_tag="OE968_003597"
     CDS             3146..3352
                     /locus_tag="OE968_003597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220829.1"
                     /translation="MISHAAEICKKYKMPFIIFPTIEKKSIEEWVNIGANMLCFAQDT
                     TFITYVINQLLSFYNEIVPIQKQH"
     gene            complement(3505..3933)
                     /locus_tag="OE968_003598"
     CDS             complement(3505..3933)
                     /locus_tag="OE968_003598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HCP7220830.1"
                     /translation="MSKIYIVYWSGTGNTEKMANFVAEGVKLKGKTPEVLDVSLLKPS
                     DLKEEDKFALGCPSMGAEQLEEGYMEPFVSELESMVSGKQIGLFGSYGWGNCEWMRDW
                     EERMQNAGATIIGGEGITAMEDPNEEAKDECIELGKTLAE"
     gene            complement(4409..5347)
                     /locus_tag="OE968_003599"
     CDS             complement(4409..5347)
                     /locus_tag="OE968_003599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family peptidase"
                     /protein_id="HCP7220831.1"
                     /translation="MNKRMKLIPYEINENLRGAKNKFPYGIKQMNARGMWDEGYTGKN
                     IVVGIIDTGCDISHPLLKGKIIGGANFSDDSNGNKNIYEDFNGHGTHVAGIIAASNYN
                     NEVMGVAPDCKLLIAKALNKDGTGTYQSIINAINFAVNNKVDIISMSLGGNKDDKNLK
                     NAVMQAVKNNISVVCAAGNNGDGDSSTSEYSYPASYAEVIEVGAINENYLVEKFSNSN
                     TTIDLVAPGRNIISTYMDNKLAIMSGTSMSAPYVSGSLALIKEWAREEFERDLDEAEL
                     YAQLIKCTRALGIPRTEQGNGYLYLNLYKYKNNSKR"
BASE COUNT         1674 a         1072 c          678 g         2026 t
ORIGIN      
        1 tcataatttt cctttttatt gcatatataa ataactgtat ataacattgt ccaatactat
       61 atagaaatac atctaagaaa gaatattatt aaattgttcc aattaatatt atttttctta
      121 tagaaataaa aaactgttgg attcttttag aaaaattatt ttttacatac cttttttgct
      181 taaatagtct atcttctcag ctattttgta tatacactct tctagttcat gattttattt
      241 taatatcttg cttatattgc tgaaataatt aaattctttt atctatcata ttgtctctta
      301 tatcacaaac atattgtttc ttatatcaca aaaatgaaag cattcttata tcttcaatat
      361 ataaacctgc tttttttaat cttgtaataa atataggata ctctatattc tcttcctaga
      421 aataactaat accacttatt tttctatcat atagaaagta ataaatcttt ttcttaataa
      481 aattcaatag taagtggaat aaaattttat atgaataaga acattataaa aatactttat
      541 acaatagtca ataaaagata ttagcttcaa attgtgttga agttgtatta tttaaagtgg
      601 aaaagcaaat aaaaaagaaa taatggtata agtagaaaaa tatacttaaa acaaggcgaa
      661 gcctctcttg tatctaaatc aagtagagaa ttaaatctaa aaaagaaaat aaatataaaa
      721 gatgactcct gtacattaca agaatcatct tatggtttca taatcactcc atggttttta
      781 actgtctgat ataaaggtct cagttcactc atagcatgac caccttttcc gattgctgac
      841 cccgtcactt atggacaaaa tgtccataag tgatagtcct ctcttaaaac cctctaaata
      901 gatatatctc aagcacctca ttgaaaccag ttgctggaaa caaactgaag cgttctggaa
      961 tagtaaaaga aattgccacc atatccacgt tactgtccta gttgttactt tgctaacttc
     1021 ggagcgattt cctctaacaa tacgcagtca aattctgcct ttttgctaag aaatggcaga
     1081 tggtctgcat ctggtataaa aaaaatctgt ttgtctggcg ccactatttc atcaaaaaat
     1141 ttcttcgctg gaagataggg gctattatag tcattttctc ccatgatgta gtatacaggg
     1201 acctgatagt caactccata atttcttatg tcagcttctt ccactaaaaa ccgcaataca
     1261 tcaccttgat tgtcaatcgc atttggattg acaatggccg tattttttaa ctctctcaat
     1321 gaataatatg gggttgccag tatactgatt atattgccca aatccatatt tatagaaagc
     1381 ccatacttgc tttggtatgt tcttactgtc ataagagctg ccaaatagct tggaccatat
     1441 tttgctggcg gatatggtgc aatagcttcc agcgccttga tatctttttg cttccctgca
     1501 gctttcacca tttcaagtgt cttttcatag cccacgcgct cattgtccac catattaaca
     1561 gtctgcgcaa tcccaatgta cgcgctgtaa tcctccggat aggtttgcac agccatagtt
     1621 cccagcactg ttccccagct atgacctata aggataattt tctccttgtt gaactcttgc
     1681 ttcaaatatg ctgtcacctc atggacgtct tgcagaacac gctccgcgct catggtctgc
     1741 aaaactgctg ccggatcgtt cgcaaagtat gttttgccta cgtttcgctg atcccagttc
     1801 accacagtaa aatcattttc ccactcatac tggtacagat gtaaaaatgg catcattgaa
     1861 ttaccaggac ccccatgaac ccaaaggatg atggggttgt ctgcgttttg tccccggata
     1921 tataacgcct gctgtatgcc gccgatctcc accatttcca tgcggtcgat tccaggagct
     1981 tctattttat ggcttgtacg tataatcgtg ggggctatca gacgcaaacc ggcaaacgcc
     2041 agaacaaaaa cagcaactag tatgcaaagt gtgattaata tcattttaag taccttcttt
     2101 catgaatttt tttagccata gatatctcct ctaacattaa aaaaagtatg ttgctatttt
     2161 agttttgtta ctctacctgt cccattggtt tcctttcata aaaaatatta attgattcta
     2221 taatctcatc ttccaggata tcaactccta tttgtctcat aagaaactgt aagaattgaa
     2281 accgtttacg aagtgtagga aagtccccct gaaatacatc tgtatcacac caaaagttaa
     2341 agagcagcaa aattacctct gcgcattcat ctgggaactc tgtgatgatg cttctatcct
     2401 ctatgccttc tcgtaaaaca tttgctaata ttggtgctag ttttttcaaa ttatcctgtg
     2461 taaatgccag tatgatatgc ggactttcta tcgcgcttgt aatcatgtta ctagattctt
     2521 ttatcacctc atccgttaaa tgccgcctaa ctaaacttct aagcttctct tttgctgtaa
     2581 gtccatgcat ttcaccgagc cattgattta ctgtctctat tatctgttca aagcgccttt
     2641 ccatgaccac attaaaaata tcttcttttg aactgaagtg atgaaaaatt ccgccctttg
     2701 acattcccga agcatcaaca atattttgca tacttgtttt gtcgtatcct ttttcagcaa
     2761 acaactttgc agaaatggta atgatatttt caatagcttg ctttggattg ttctttctag
     2821 tcattatata actccttctt attaaaaacc gactgttggt ttttattata taagctattc
     2881 ctgcttctgt caagtaacat tgtgtttatg gcaaaacaat aaggtttggt ggttagacag
     2941 gtattaatta gactaatgcg actttcccct agatggaacc cttggtaaat ttgcaatctt
     3001 taccggcttt gattatatct gtaagcaagg caggtatggc cacgcctgcc ctgtttgacc
     3061 ctcggatatt cattcctatc cctcctctcc ttagccatta caccaaaacg ccgctcattg
     3121 tctccaatgg cggcgtttta aagatatgat ttctcatgct gctgaaatat gcaaaaaata
     3181 taagatgccc tttattattt ttcctacaat agaaaagaaa agtattgaag aatgggttaa
     3241 tattggagca aatatgcttt gttttgcaca agatactacc tttatcactt atgttatcaa
     3301 tcaattatta tctttttata atgagattgt accaattcaa aaacaacatt aaattataaa
     3361 tctaatttta tattaaaaga gactaatatt ttatctatct ctattaagga tattttctta
     3421 tgtatcataa tattagtctc tcttattatt atatactgct atcatcatta gttgttattt
     3481 atactatttt tataatatac aaatttattc agctaacgtt ttgcctaatt ctatacactc
     3541 atcttttgct tcttcatttg ggtcttccat tgctgtaatt ccttctccac caataattgt
     3601 agcaccagca ttttgcatac gttcttccca gtctctcatc cattcacaat ttccccatcc
     3661 atatgaacca aataatccaa tctgtttacc tgataccata gattctaatt ctgaaacaaa
     3721 tggctccata tacccctctt ctagttgctc tgctcccata gatgggcaac ctaatgcaaa
     3781 tttatcttct tcttttaaat cacttggttt cagtaagctc acatctaaaa cttctggtgt
     3841 cttacctttt aacttcacac cttcagccac aaaatttgcc attttttcag tatttcctgt
     3901 tccactccaa taaacaatat atattttact catttttacc tcctgtagta ttttttaatt
     3961 aatcaatagt tagttatagc taactaacat ctaaaaaaca aaagatttct ttatctgaaa
     4021 tctctttatt tttctaaata tagaatatca tagttgatat tgaaattcaa tacttattga
     4081 taatatttat catttatatt ttatattcat tttataatat caaaacactg tatcgtattt
     4141 ctaatctttc atagaaaaat ttctaactta tagtactttt gcatctctta taaatctttt
     4201 atatgtataa gtacatagaa aaacacacct tttccagatg tgctatctat aatatcgtat
     4261 atttattttt caattctaac tagctaatat gtttataaat tttatcactt aataccttta
     4321 tacattgatg taaaatctta cacctaagta atttttatta tttgtctcga ctctatataa
     4381 tatagctatt ttatcatcaa atcaaaaatt atcttttact attattcttg tatttataga
     4441 gatttaaata taagtatcca tttccttgtt ccgttctagg tattccaagc gctctcgtac
     4501 attttattaa ttgtgcatac agttcagctt catctaaatc tctttcaaac tcctctcttg
     4561 cccattcttt aattagtgct aatgagcctg atacgtatgg tgcactcata ctagtaccac
     4621 tcataatagc aagtttatta tccatataag ttgatataat atttcttcct ggagctacca
     4681 aatctattgt agtatttgaa ttactaaact tttcaaccaa atagttctca tttattgcac
     4741 ctacttctat tacctcagca taactggctg gataactata ctcacttgta ctagaatcac
     4801 catctccatt attacctgct gcacacacta cagaaatatt attttttact gcttgcatga
     4861 cagcattttt taaattctta tcatctttgt ttcccccaag agacatagat ataatatcaa
     4921 ccttgttatt tacagcaaag ttaatagcat taattatact ttgatatgtt ccggtaccat
     4981 ctttatttaa tgcttttgct attaataatt tacaatctgg agctactccc ataacttcat
     5041 tattataatt agatgcagct ataatacccg ccacatgagt tccatgacca ttaaaatcct
     5101 catatatatt tttatttcca ttactgtcat cactaaaatt tgcaccacca attatttttc
     5161 cttttaaaag aggatgagat atatcacaac ctgtatctat tataccaact acaatatttt
     5221 taccagtata accttcatcc cacattcccc tagcattcat ttgttttatt ccatatggga
     5281 atttattttt tgcacctctt agattttcat ttatttcata tggaattagt ttcattcttt
     5341 tattcatcat atatcctcct aaaaatttta ttgcttataa aaatcatgaa ttttatttta
     5401 taataggttt ataaatcaaa ttaaaaccta tatctactta tttatattta
//
LOCUS       DAJMZY010000170         5394 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.175, whole genome shotgun sequence.
ACCESSION   DAJMZY010000170 DAJMZY010000000
VERSION     DAJMZY010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5394)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5394)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5394
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.175"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            338..1864
                     /locus_tag="OE968_003600"
     CDS             338..1864
                     /locus_tag="OE968_003600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HCP7220832.1"
                     /translation="MNESYWFLNSSPKEYNKLGENIKTDCLIVGGGITGLTTAYLLAK
                     EGKKVVLVEADKIGYGTSGRNTGKVTCQHDIFYSKIEKKYGLDKAKSYYNANNEALNL
                     VEQIIEENNIKCDFKRETSFVFTEKEDTIKDIKDEYRTCKKIGINCEYHETIENIPLD
                     IKGAISFTNQGQFNPKKYIDGLAKAAVNLGLKIYENTPVVDLEKGKICRVKTREDNII
                     EAENVIISSHSPWYDGLNFYFAKEYAERAYLMVAVLENKLADGMFISIDDPSITFRQY
                     NDGSENLLIFGGGDHKVGQGGTEKEIFDDLEHYGKEVFKVKDFKGKWSAQDNMSFDNV
                     PYIGYINKREDNIYVATGFSKWGITNGTAAGIIIKDLIINNNSDYKDTFNPSRLGSYF
                     SKDFIKENANVAINYVSGKLKIGSGDMPKNNGEGKIVNIDGKRYGVYKDDNGDFYIVD
                     TTCTHLGCELNFNSEEKTWDCPCHGSRFDYKGNILEGPALKPLKLYGHGDNDVNPKLL
                     "
     gene            1892..2449
                     /locus_tag="OE968_003601"
     CDS             1892..2449
                     /locus_tag="OE968_003601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220833.1"
                     /translation="MNKLLKPITILLYIVYILSAVFFVANKEYGSLGLVAISLVGTFI
                     LSFINKQTERLLSKELYIMLALFIMFSSLLGTCFNFYDINYYDDFLHLWSGIISCIVA
                     FSIIKYFYTQREISKMSKVFLVIFLFMFSMGVASLWEIGEFLMDTFVGTTTQAGGLED
                     TMIDMVDALIGTIITIPFIVKKSNI"
     gene            2971..4014
                     /locus_tag="OE968_003602"
     CDS             2971..4014
                     /locus_tag="OE968_003602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220834.1"
                     /translation="MLKKWFGIVKKRQKSESAKEEGEVILKNEKILSEEKLIDEEGVV
                     VNIDNEILTKVEVVNDDNEIEEKIIEEDWLISENTIKLDDKEAIINDKNIELCKKEVQ
                     VESEKIGLNKFEGLDQNENYNLEKNVIEEKKVSECLTEEDLEYIKEIKIKRGKSIKAI
                     NLYTKEEWVFDTHIQCSKKLKVPLGYIRENLKYGYMDYFGDAINYLSEVLNIDEYCKS
                     EWSYLDNSKSPSEIFNILNNKIFSIRLSNEKRNEILTNDKIEALKMNYRFECIDEEYD
                     EYFKKYKSIIKRGGKKKVELVNKKGDILEIFKSLEECAIYLQKEKNEVIQMLKYGDTK
                     VGRNFIRYSLRSI"
     gene            4125..5266
                     /locus_tag="OE968_003603"
                     /pseudo
     CDS             4125..5266
                     /locus_tag="OE968_003603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440250.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
BASE COUNT         2279 a          446 c          947 g         1722 t
ORIGIN      
        1 tttttataga gagattgtta tattacatat cagaaaaata ttaaactaac taaatcaata
       61 aaaaagttgg tggataacaa tttataattg ttagcacaac atcatcttat gtattgaaat
      121 ctaaaatatc ctcattttta cttagcataa atactattaa ttaagaaaat aatatagaaa
      181 ttataaatat atataagttt agtctggtgt ataaaacaag aaaactaagt gatttttaat
      241 ttaacttttt attaagctta ttttttatac tatttataat aaataaactc catgatggga
      301 aaactattac tatttaatat gtaaaggagt attttaaatg aatgaatcat attggttttt
      361 aaactcaagt ccaaaagaat ataacaaatt aggtgaaaat ataaaaacag attgtcttat
      421 agtaggtggt ggaataactg gattgacaac tgcatattta ttagcaaaag aaggtaaaaa
      481 agtagtgctt gttgaggctg ataaaatagg atatggaact tctggaagga atactggtaa
      541 ggtaacttgt cagcatgata tattttactc taagatagag aaaaaatatg gattagataa
      601 agcaaaatca tattataatg caaataatga agctttaaat ttagttgaac aaataataga
      661 agaaaacaat ataaaatgtg attttaaaag ggaaacttct tttgtattta cagaaaaaga
      721 ggatactata aaggatatta aagatgaata tcgtacatgt aaaaaaatag gaataaattg
      781 tgagtatcat gaaactatag aaaatattcc attagatata aagggggcta ttagttttac
      841 taatcaaggt caatttaacc caaagaagta tattgatgga ttggcaaaag cagcagtaaa
      901 tttagggcta aaaatatatg aaaatacacc agtagtagac cttgaaaaag gaaaaatatg
      961 tagggttaaa acaagagagg ataatataat agaagctgag aatgttataa tttcatctca
     1021 tagtccatgg tatgatggat tgaattttta ttttgcaaaa gaatatgcag agcgtgctta
     1081 tttaatggtt gcagttttgg aaaataaatt agcagatggt atgtttataa gtatagatga
     1141 cccatcaata acttttagac aatataatga tggaagtgaa aatttactga tttttggagg
     1201 aggagaccat aaagttggtc agggaggaac tgagaaagaa atatttgatg atttagagca
     1261 ttatggtaaa gaagtcttta aggtaaaaga ttttaagggg aaatggtctg ctcaagacaa
     1321 tatgagtttt gacaatgttc cttatattgg ttatatcaac aaaagagaag acaatattta
     1381 tgtagctaca gggttctcta aatggggaat tactaatgga actgctgctg gaataataat
     1441 aaaagatttg ataataaata ataattctga ttataaagat acttttaatc catccagatt
     1501 aggtagctac ttttcaaaag attttataaa ggaaaatgca aacgtagcaa taaattatgt
     1561 aagtggaaaa ttaaaaatag gtagtggaga tatgcctaaa aataatggag aaggaaagat
     1621 tgttaatatt gatggaaaaa gatatggtgt atataaggat gataatggag atttttatat
     1681 tgtagacact acatgtactc atttaggatg tgaacttaat ttcaacagtg aagaaaaaac
     1741 atgggactgt ccatgtcatg gttctagatt tgactataag ggaaatatac ttgaaggacc
     1801 agctcttaag ccattaaaac tttatggaca tggtgataat gatgttaatc ctaagttatt
     1861 ataaaattat ttttaggaag gtaaagtgta tatgaataaa cttttaaagc caataactat
     1921 actattgtat atagtttata ttttatctgc cgtatttttt gtagcaaaca aagaatatgg
     1981 aagtctaggt ctggtagcaa ttagtttagt tggtactttc attttgagtt ttataaataa
     2041 gcaaacggaa agattattga gtaaagaatt atatataatg cttgctttat ttataatgtt
     2101 ttcatcattg ttaggtactt gttttaattt ttatgatata aattattatg atgatttttt
     2161 gcatttatgg tcaggtataa tatcttgtat tgtggctttt tctataatta aatactttta
     2221 tacacaaaga gagataagta aaatgagtaa agtgttttta gttatatttt tatttatgtt
     2281 tagtatggga gtagcgagtt tatgggaaat aggtgaattt ttaatggata cttttgttgg
     2341 gactactaca caggccggag ggttagaaga tactatgatt gatatggtag atgctttaat
     2401 aggcacaatt ataactattc cttttatagt aaaaaaatct aatatatagt tttaaatttt
     2461 ttatattaat tataatggat ttaattaatc atgttgagtt tcaaggtcta tatgattaat
     2521 taaatccatt tttgttattt ataattatta ttgaatatat ttttacatat aagatataag
     2581 gtgatagata gaaattgttg gattatgtaa ataattaata tataatacca ttatgggcaa
     2641 taaatacaaa tcaaatgata atatagtcta tttatgtaaa tgttatattg tatactaagt
     2701 ataatagtaa gttttttgat agtggtgtag aaagtaaaaa tctactagcc taaattgatg
     2761 tatggattag tttaggaaca gtaattgcat atcttaagtt tgatgtcatg ttgggctact
     2821 agaaataggt catctttttc acttgaatat cttttcttta aacatggaga gtatcatatc
     2881 aaaaacatat gaaaattaag tgatttataa gaacagtaat attttatatg atagtataga
     2941 atagtaataa agtattagga ggaacattga gtgttaaaaa agtggtttgg tattgtgaaa
     3001 aaaagacaaa aaagtgagtc agcaaaagaa gaaggtgaag taatattaaa aaacgaaaaa
     3061 atattatctg aagaaaagtt gatagatgaa gaaggagttg tagttaatat tgataatgaa
     3121 atattaacta aagtagaagt agtaaatgat gataatgaaa tagaagaaaa aataatagaa
     3181 gaagattggt taattagtga aaataccata aaattagatg ataaagaagc aattattaat
     3241 gataaaaaca tagaattatg taaaaaagaa gttcaagttg aaagtgaaaa aataggttta
     3301 aataagtttg aaggacttga ccaaaatgaa aattataatc tagaaaaaaa tgttattgaa
     3361 gaaaaaaaag taagtgaatg tttgacagaa gaagatttag agtacataaa agaaattaaa
     3421 ataaaaagag gaaaaagtat aaaagctata aacttgtata ctaaagaaga gtgggttttt
     3481 gacactcata tacagtgtag taaaaaactc aaagttccat tagggtacat aagagaaaat
     3541 ttaaaatatg gatatatgga ttactttgga gatgcaataa attatttaag tgaagtatta
     3601 aatatagatg aatactgcaa aagtgaatgg agctatctcg ataatagcaa atctccatct
     3661 gagatattta atattctaaa caataaaata tttagtataa ggctttctaa tgaaaaaaga
     3721 aatgaaattt tgacaaatga taaaattgaa gcattaaaaa tgaattatag atttgaatgt
     3781 attgatgaag aatatgatga atattttaaa aaatataagt ctataatcaa aagaggtgga
     3841 aagaaaaaag ttgaattagt aaataaaaaa ggtgacattt tagaaatatt taagtcttta
     3901 gaagaatgtg ccatttattt gcaaaaggaa aagaatgaag ttatacaaat gttaaaatat
     3961 ggagatacaa aagtaggaag aaactttata aggtatagtt tgagaagtat ttaatttcat
     4021 tttaaattca taagagtttc atttctgatt cacacattta atattatttt aatgtaaaat
     4081 aataaaggtg aagtattgca caattaaaat taaggagggt attaatgtct gaagaaaaaa
     4141 atccaaaaga aaatacatta gatgaatcta aaaattcaga taatgtaaat tctaaaaaag
     4201 atgatgtgtc agatgaaaaa aatactgata acaaagttaa aaaaagggaa ataaagctaa
     4261 acaacaaaac acttaaagct attgtagcaa ttgttgcagt aggagctata tgtttaggtg
     4321 gaggctatgt ttttggcaaa gaagctggaa gaaaattgcc tgctacttca aaacactata
     4381 atagcagtga ggtagtagct actattgggg ataaaaaata acaggtgaaa tgttaagaaa
     4441 gagaatggag ccattatttt atttaaatgc aaaaactact atgactgatg acgaaatacg
     4501 ttcatatgaa tcaaatatga ttgaaactat gattacatct gatatattat cctctgaagc
     4561 agcaaaagag aaaataagta taactaatga ccaactagat gctcagtata ataatttaat
     4621 gagtagtata gaatcagcaa tgggaatgac taaagaagag tttttaaaac agtttgattt
     4681 gactgaaaaa tatataaaag atgatatgaa aaaagagcta gtagcatcaa aatatttaaa
     4741 tgaaaaatca aaagttactg ataaagaagc agagaactat tacaataaaa acaagagcaa
     4801 ttatttacaa gttagagctt cacatatttt aataaaaact gttgatgata aaggtaagca
     4861 agttagtagt agcaaaaaag ctgaacttaa gaaagaagct gaagaaatac ttaaaaaagc
     4921 ccaagctggg gaagattttg ctactctagc taaaaaatac tctgaagata gtagtgcaga
     4981 atcaggtgga gatttaggtt tctttggtaa aggtcagatg gtggaatctt ttgaaaaagc
     5041 agcctttgca ttgaagaagg gagaggtatc taacaaactt gtagaaagtg attatggata
     5101 tcatataatt aagaaaactg atgaaaaata tcagccattt gaagaggtaa aatcagattt
     5161 agtaagcagt ttaacatcag aaaaacaaaa cctacttata caaaatctaa aagaaaaata
     5221 taatgttaaa attacagata aatatcaaat gaaagctaaa gaatagataa agtcaattta
     5281 ttaaaaaaaa gaaaaattaa ctgtatggat aaaagctatt tttactctta atatagagag
     5341 tataaaatag cttttattat tttgcaataa aatctattta tatatatgaa gtga
//
LOCUS       DAJMZY010000171         5066 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.176, whole genome shotgun sequence.
ACCESSION   DAJMZY010000171 DAJMZY010000000
VERSION     DAJMZY010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5066)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5066)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5066
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.176"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            100..711
                     /locus_tag="OE968_003604"
     CDS             100..711
                     /locus_tag="OE968_003604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA pyrophosphatase"
                     /protein_id="HCP7220835.1"
                     /translation="MINDIKNKFKNYKPYINGYKNMKRASVLIPIVEINNTHYILFEV
                     RSKNLKHQPSEISFPGGKIESGETPYEAVIRETCEELGTFSDNIEVISSLDLLITPVK
                     FIIHPYLGYIKNINNLNINKDEVDHTFLVPIKYLLENPPNTYSNTVKVFPDENLPYGS
                     IPNQKDYKFESGSYPILFYKYKDYVIWGMTAKILENFLNFLSE"
     gene            1009..1347
                     /locus_tag="OE968_003605"
     CDS             1009..1347
                     /locus_tag="OE968_003605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3784 domain-containing protein"
                     /protein_id="HCP7220836.1"
                     /translation="MFAVGFVVIIALAFFILSVLLFNGKASMLLAGYNSMSKKEKARY
                     DKKKLCRSSSIVTFIVSIMLFIMAFLGYRIESGQMDEKKMVPFSIIFIIVILSSVFFN
                     ILYSNKKCKK"
     gene            complement(1754..3190)
                     /gene="miaB"
                     /locus_tag="OE968_003606"
     CDS             complement(1754..3190)
                     /gene="miaB"
                     /locus_tag="OE968_003606"
                     /EC_number="2.8.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (N6-isopentenyl
                     adenosine(37)-C2)-methylthiotransferase MiaB"
                     /protein_id="HCP7220837.1"
                     /translation="MSKRKQVTIPIEKIQEQDKYIEQIHRQNEEYFNRTGKRKLVFTQ
                     TFGCQMNEHDSEKLCSMLEEMGYQMSMMVEESDLIIYNTCAVRENAELKVYGNLGQLK
                     HLKGKNPDMKIAVCGCMMQQPHVVEELRKKYKHVDLIFGTHNLYKFPQLLTESINSDK
                     MLVDVWDVDGEVIEGLRSNRKFELKAFVNIMYGCNNFCTYCIVPYTRGRERSRTPEDI
                     INEIKELVANGTKEITLLGQNVDSYGKTLENPVSFSELLRKVNDIEGIERVRFMTSHP
                     KDISDEVIYAIRDCDKVCEFLHLPIQCGSSSLLKKMNRHYTKEYYLEIIEKAKKEVPG
                     IAFSTDLMIGFPGETEEDLLDTLDVVEKVRYDSAFTFIYSKRQGTPAAKMENQIPEDI
                     KHDRFNRVLEAVNRISAEINDGYKDRIVEVLVEGRSKNNENKFAGRTRQNKLVNFEGG
                     NDDLIGKLVMVKITEPRTFSLNGILVNN"
     gene            complement(3438..4898)
                     /locus_tag="OE968_003607"
     CDS             complement(3438..4898)
                     /locus_tag="OE968_003607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp28"
                     /protein_id="HCP7220838.1"
                     /translation="MKFYKRILTLTLSISFVFANIQLVDAISSVEKIQGKNKYEIAGK
                     IADKNAYKTAYKTAYKTAILINTSNSIADGLSASGLAGALNAPILLTEKNTIPTETSA
                     RLKNVSKVYIIGGTYSISTSVENSLKSKKMKVVRIKGNDRIKTSYNVAKEINSIKKVN
                     TVMLTNAYKGEADAISIASVAARDKAPIILTNGQSIPFSTSGLKSYVIGGTASMSTTL
                     VNNTKSTRLGGSTRFETNKAIINKFYKDAREFYIAGAYELTNALVGSSLSKHGPMVLV
                     NDGSNKSILKNAKKITSIGYIDSNIVQQCLNITNGIGDINTGVVKNVKPTTKTIKDGM
                     YKVGKDISAGEYLITSNSGSYASYYEVTSDSTGNADSILSNDIFSGTRYITLKNGQYI
                     KIEDSTMTLAKYAKAQKAKNGKFGNGMYKIGLEIPAGEYIIMSNSSDAYYEVRNDSLG
                     NAEGIVTNDTFSGRRYITVEEDQYLILNDCYLIENE"
BASE COUNT         1720 a          763 c          550 g         2033 t
ORIGIN      
        1 agatagttac tatatcttat aattagataa atcataatta tatattattg ttaaaactca
       61 attatataat ttttaataat attattttag gaggtaaaaa tgataaacga tattaaaaat
      121 aaattcaaaa attacaaacc atatataaat ggatacaaga atatgaagag agcatctgtt
      181 ttaattccaa tagtagaaat aaataacaca cactatatat tatttgaagt tcgctcaaaa
      241 aatttgaagc atcaacctag tgaaatttct tttccaggtg gtaaaataga atcaggtgag
      301 actccatatg aagctgttat tagagaaact tgtgaggaac ttggaacttt tagtgacaat
      361 atagaagtaa tatcaagtct tgacctcctt ataacaccag taaagtttat catacatcca
      421 tacttaggat atataaaaaa tattaataat ttaaatataa acaaggatga agttgaccat
      481 acttttttgg ttcctataaa atatctttta gagaatcctc caaatactta tagtaatact
      541 gtaaaagttt ttccagacga aaatctacca tatggttcaa ttccaaacca aaaagattat
      601 aaatttgaaa gtggaagtta tcctattctg ttttataaat ataaagatta tgtaatttgg
      661 ggaatgacag caaaaatact agaaaacttt ttaaattttt tatcagaata acactcataa
      721 taaatcatca aaacttttac ataagaaatt tataaaagtt tctaaattta acaattctaa
      781 aatatcaata actatatttt gtagcacttt tttattttat tattgtttga atatttgatg
      841 gttttcaatg caatttcaac ataaatacta tgtattagtg tatactgttg atgaattaaa
      901 gtatgataat ctatttaata aagtatgaag taaatgattt taatgtgcct ttatggtaaa
      961 attactaata agtaataaaa ttaattaaaa tatatggagg tgcttataat gtttgctgta
     1021 ggatttgttg ttataattgc acttgccttt ttcattttaa gtgtactatt atttaatgga
     1081 aaagccagta tgctactagc aggttataac tctatgagta agaaagaaaa agcacgatac
     1141 gataaaaaaa aattatgtag aagttctagc attgttactt ttattgtctc tataatgcta
     1201 tttattatgg cgtttttggg atatagaata gagagtggtc aaatggacga aaaaaaaatg
     1261 gttccctttt ctataatatt tataatagtc atactttcca gtgtattttt taatatcctc
     1321 tactctaaca aaaaatgtaa aaaataaata gttgtaagtt gagcagttaa ttataaaaga
     1381 ttgactgctt tttcatgtat attgactact cttattaaat attttaacat ttaaaaatct
     1441 atgtaaaaat aatgaatata gtacaaactt ctaataatga ttttaccttt gtggttacag
     1501 tccactatat ataatttaat atgataacag ggaattacta atgacaacta ggtaagcttt
     1561 tataaaatat aataaaacaa aaatagatgt acaatgaaat tatatcttat atcaaattta
     1621 tttttattaa tagcaaaaac ttacattagc ataacatatg acaaattcgc ttaaaataaa
     1681 aatttttaat ataatttgtt ctatagtaca tctattttga ttagtttaca taattttatt
     1741 attttgtaca atattaatta tttactaata tcccatttaa tgaaaaagtt ctaggttcag
     1801 taatttttac cataactaat ttaccaatta aatcatcatt tccaccttcg aaatttacga
     1861 gtttattttg tctagttcta ccagcaaact tattttcatt atttttactt cttccttcaa
     1921 ctagaacttc aactattcta tctttatatc catcatttat ttctgcagaa atcctattta
     1981 cagcttctaa caccctatta aatctatcat gctttatatc ttctggtatt tgattttcca
     2041 ttttagcagc aggagttccc tgtcttttag aataaataaa tgtaaaagct gaatcatatc
     2101 taactttttc aaccacatct aaagtgtcca ataaatcttc ttctgtttct cctgggaaac
     2161 caatcattaa gtctgtagaa aaagcaatac ctggaacttc ctttttagct ttttctatta
     2221 tttctaaata atattccttt gtataatgtc tattcatttt tttcaaaagg ctactgcttc
     2281 cacattgtat tggtagatgt aaaaactcac acaccttatc acaatctcta attgcgtata
     2341 ttacttcatc agatatatct tttggatgag atgtcataaa tcgaaccctt tcaattcctt
     2401 ctatatcatt cacttttctt aaaagttctg agaatgaaac tggattttca agtgtcttac
     2461 cataagaatc tacattttgt ccaagtaaag tgatttcttt cgttccattt gcaacaagct
     2521 cttttatctc gttaattata tcttcaggag ttctacttct ttctcttcct cttgtgtatg
     2581 ggactataca atatgtgcag aaattattgc atccatacat tatatttaca aatgctttta
     2641 attcaaattt tctattactt ctaagacctt ctattacttc tccatccaca tcccatacat
     2701 ccactaacat tttgtcagaa tttattgatt ctgtaagtaa ttgcggaaat ttatatagat
     2761 tatgtgttcc aaatataagg tctacatgtt tatatttttt tcttaattcc tctacaacat
     2821 gtggttgttg catcatacat ccacatacag ctattttcat atctggattt tttcctttta
     2881 gatgttttaa ttgtcctaag ttaccataca cttttagctc tgcattttct ctaactgcac
     2941 aggtgttata tattattaaa tcactttctt caaccatcat tgacatttgg tatcccatct
     3001 cttctaacat tgaacataat ttttctgaat catgttcatt catttgacac ccgaaggttt
     3061 gagtaaacac gagttttctc tttccagttc tgttgaagta ttcttcattt tgtctgtgta
     3121 tttgttctat atatttatct tgttcttgta ttttctctat aggtattgtt acttgttttc
     3181 ttttgctcac gtctattcct cctagttaat ttcttatatt acacataacc ttaattatat
     3241 caaataagaa aaatctttta aagatattat tatttttcta gttgtgtttt aatagtaaat
     3301 ctaatgattt atatatacta tatttctaaa atataaaatc atataattat tataataata
     3361 aaaagatgtt ttaaattaaa acttaaaaca cctttcctta aataaaatat atgatttact
     3421 attaaataca attacatcta ttcattttca attaaataac aatcatttaa tattaaatat
     3481 tgatcttcct caaccgttat atatcttctt cctgaaaaag tatcattagt aactattccc
     3541 tctgcattac ctaagctatc atttctaact tcataatatg catcagaaga atttgacatt
     3601 ataatatatt ctccagcagg aatttctaat ccaattttat acataccatt tccaaactta
     3661 ccattcttgg ccttctgggc tttagcatac tttgctaatg tcattgttga atcctcaatt
     3721 ttaatatatt gaccattctt taaggtgata tatctagtcc cactaaaaat atcatttgaa
     3781 agtatactat cagcattacc tgtactatca cttgtaactt cataataaga agcataactt
     3841 cctgagtttg aagttattaa gtattcacct gctgagatat cttttccaac cttatacatt
     3901 ccatctttta tagtctttgt agtaggttta acatttttta caaccccagt attaatatct
     3961 ccaattccat ttgttatatt taaacactgt tgtactatat ttgaatctat atatcctata
     4021 gaagttatct tcttagcatt ttttaaaatg cttttattgc taccatcgtt aactaaaacc
     4081 attggaccat gttttgataa agaagatcct acaagtgcat ttgttaattc ataagctcca
     4141 gctatataaa actctctagc atccttataa aacttattta ttattgcttt attagtttca
     4201 aaacgagtac tcccccctag tctagtagat ttagtattgt ttactaaagt ggtactcatt
     4261 gaagctgttc ctcctattac ataagacttt aaaccactag ttgaaaaagg tatactttgt
     4321 ccattagtaa gaattattgg tgctttatct cttgctgcta cagatgcaat acttatagca
     4381 tctgcttctc ctttatatgc attggttagc ataacagtat tgactttttt tattgaattt
     4441 atttcttttg caacattata acttgttttt attctgtcat ttcccttaat tcttacaact
     4501 ttcattttct tagattttaa tgaattttcg acagatgtac taatagaata tgttcctcca
     4561 attatataaa cttttgatac attttttaat cttgcagatg tctcagttgg tatagtattt
     4621 ttttcagtta atagtatagg ggcatttaaa gctcctgcta gtccacttgc acttaatcca
     4681 tctgcaatag agttactagt attaattaat atagcagttt tatatgcagt tttatatgca
     4741 gttttatatg catttttatc tgctatttta cctgctattt catacttatt ttttccttgt
     4801 attttttcta cagatgatat tgcatctact aattgaatat ttgcaaatac aaaagaaata
     4861 cttaaagtca atgttaatat tcttttatag aatttcataa taaaattgtc cccctcataa
     4921 taaattttta atatataaat acatattctt aaattagtta tgtacttaac aaacttatgt
     4981 aaaattgcaa attatattaa gtatattaca aataaatatt aatacaatta ttcatttagc
     5041 tataattgta tttacattta tattaa
//
LOCUS       DAJMZY010000172         4951 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.177, whole genome shotgun sequence.
ACCESSION   DAJMZY010000172 DAJMZY010000000
VERSION     DAJMZY010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4951)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4951)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4951
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.177"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            478..1338
                     /locus_tag="OE968_003608"
     CDS             478..1338
                     /locus_tag="OE968_003608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HCP7220839.1"
                     /translation="MKIIQILNNNVALVKRGKNEIIVFVKGIGFKKRVGQVINENEIE
                     RTYILDSYDMLEHFSYLLQNSDSNNIVLINEIIEYGEKALNIKASDYLSLTLLDHLEF
                     LLKRCEKNQFIKSPLVWNVKRFYPKHFEIGMHALKLIGDSKGINLPDDEAVSIALHFV
                     NMEVNKESHDSTIVELRTLADIVSIIKYHFNVELDETSTNYMRFTTHLQYFIQRIMSD
                     EASIDEDNSIDLYKQVSQLYPKSFGSVQKIRKYIKSQFNVDISISEETYLMLHINRVT
                     QRLEAKSDEI"
     gene            1328..3199
                     /locus_tag="OE968_003609"
     CDS             1328..3199
                     /locus_tag="OE968_003609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HCP7220840.1"
                     /translation="MKYKDLNENIIKLIGGKENIKSVAHCVTRLRFTLNDRSIAQTEE
                     IKKLKGVIDVVSNDVAYQIIIGTHVVDVYNEFMSMIGLSSSESSIKSERKKGIRGIKG
                     IFNSIFVVVSETMTSVIEVLLAAGILASILALLNMSGILQSDSPTYQILDTLRSATFH
                     FLPVLIAIASAKRLNVNPYIAVVLAVTLLSSSIDGVEGLSLFGINLQATTYANSFIPI
                     LLGVWAMGIIIEGLKKILPKALHYFLVPVLSLIITLSVTLTVFGPIGMWIGDGLNYAC
                     MFLIDTLGNWSVVALYAALQPLLIVFGAANFTMPISLNSVTTLGYDPIFMGAATISDI
                     AVCGAMFGYFLKTRNKEQKQLFGTVSFSALMGVTEPSVFGVFMKYRRPFVAVMIGGGI
                     GGLIAGLAQVKTYGMVWGLAALPTYLVGGEVSNFTFMIISVVVSFVAATAASYLLGIP
                     SDEKEEVKGDNEKELELIINENNSRTISIGNVAKGQVIALGEVNDKAFSSGALGKGVG
                     VIPSESKSTVISPVDGTITIVFPTKHAYGIVTDEGLEILIHIGIDTVNLDGKFFESLV
                     TQNQRVKKGDALAVFESDKIIEEGFDSTIITVVTNTSDYLDVISSNDESEELLTVIV"
     gene            3219..4673
                     /locus_tag="OE968_003610"
     CDS             3219..4673
                     /locus_tag="OE968_003610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HCP7220841.1"
                     /translation="MNIKDTFFWGGSIAAHQCEGSWDSDNKGPAIMDFVTKGSYETPR
                     VITDKIEEKLDYPSHNGIDFYNRYKEDIALFKEMGFSALRISIDWSRIFPNGDDENPN
                     ELGIKYYEGLIDTLIENNIEPIVTLYHFELPMNLVHKYGSWNNRKLIDLYLKYSETVI
                     RRFDDKVKYWVTFNEMNHIDPQTEHSDIFTYMIAGIKYSEIENKVQTLANVGYNMTLA
                     GVKVAKLAREINPNNKIGCVFGLNPIYPYNCNPSNVLNAFLDNDRDYYQIDAMCNGKF
                     PQYKLKEYEKNNITIEVTDEDKKAFKEGKLDFIGLNYYFSSVSTPKENLSGDKSLFGG
                     IQNPYLEQSKWGWAIDPIGLRFTLNYIYRKYQLPILITENGLGAYDKIEEDGTINDDY
                     RIEYLSKHLSQMKSAIEEDNVECFGYLMWGPIDLVSATTGQMSKRYGFIYVDLDDEGK
                     GSFKRYKKKSFDWYKEVIKSNGEVLDFSTDIVVG"
BASE COUNT         1907 a          521 c          900 g         1623 t
ORIGIN      
        1 aactaaattt gaagctttac ctattaatat atcttaatag tgattaaata aaactaaact
       61 taagacttta tatgttaata tatcttaaga atttatttgt taacatacag ttcattatat
      121 ttaaaagcat tactatgata attcataata gtaaaataga taatggttca gacaatatta
      181 taaatattag tgacggtaaa atagtatcaa tttagtatat aaaccttgtc agataatcgc
      241 ataacagagc ttgtagttat agaataaaaa aatatctagg aaaccgttga cagatttata
      301 tggatagtat aacatataga atatgaaatt aaacaaaaaa gaattttaat tatggcgacg
      361 tagtcataat tttgagtatg ttactgatta gcaggcagaa ctcaagtata tatgtgaaaa
      421 atagagggat actctataca tatatgcttg agttcttttt attgaaagga ggaatatatg
      481 aaaataattc agattttaaa taataatgta gccttagtaa aaagaggtaa aaatgaaatt
      541 attgtatttg ttaaaggaat tggctttaaa aaaagagtgg gacaagtaat aaatgaaaat
      601 gaaatagaga gaacatatat actagattca tacgatatgc tagaacactt tagttatcta
      661 ctacaaaact cagactccaa taatatagtt cttattaatg aaataattga atatggtgag
      721 aaagctttaa atataaaggc aagtgattat ctaagcttaa ccttactaga ccatttagag
      781 tttttactta aaagatgtga aaagaatcaa tttataaaaa gtcctttggt atggaatgtt
      841 aaaagatttt atccaaagca ttttgaaatt ggaatgcatg cactaaaatt aattggtgat
      901 agtaagggaa ttaatcttcc tgatgatgag gcagtatcaa tagcacttca ttttgtaaat
      961 atggaggtaa ataaagagtc tcatgatagt acaattgtag agttgagaac tttagcagat
     1021 atagtttcta taataaaata tcattttaat gtagagctag atgaaacttc aacaaattat
     1081 atgagattta ctactcatct acagtacttt atccaaagaa ttatgtcgga tgaagcttca
     1141 atagatgaag ataattctat agatttatat aaacaagtaa gtcaacttta tccaaagtca
     1201 tttggaagtg ttcaaaagat aagaaaatat ataaaatcac aatttaatgt cgatatatct
     1261 ataagtgaag aaacttattt aatgttgcat ataaataggg tgactcaaag actggaggca
     1321 aaatcagatg aaatataaag atttaaatga aaatataata aaacttatag ggggaaaaga
     1381 aaatataaag tcggtagcgc attgtgttac tcgtttaaga tttactttaa atgataggag
     1441 tatcgctcaa acagaagaaa ttaaaaaatt aaaaggagta attgatgtag tttctaatga
     1501 tgttgcttat caaattataa taggtactca tgttgtagat gtatataacg agtttatgtc
     1561 tatgataggt ttaagttcaa gtgaatcaag tataaaaagt gaaagaaaaa agggaattag
     1621 aggtatcaaa ggtatattta attccatctt tgtggtagtc tcagagacta tgacttcagt
     1681 aattgaagta ctacttgcag ctggtatact tgcaagtata ttagcacttt taaatatgtc
     1741 tggcatactt cagagtgaca gtcctacata tcaaatatta gatacattaa gaagtgctac
     1801 atttcacttc ttaccagtat taattgcaat agcatcagca aaaagactta atgtaaatcc
     1861 ctatatagca gtagtgttag cagttacgtt attatcttca tcaatagatg gtgtagaagg
     1921 attaagttta tttggtataa atttacaggc tacaacttat gcaaacagtt ttattccaat
     1981 acttttagga gtatgggcaa tgggaattat aattgaaggt ttgaaaaaaa tattacctaa
     2041 agcattacac tattttttag ttccagtgtt atctttaata ataactctat cagttacatt
     2101 aactgtattt ggacctattg gtatgtggat tggtgatgga ttaaactatg catgtatgtt
     2161 tttaattgat acattgggta attggagtgt tgttgcactg tatgcagctt tacaaccact
     2221 cttaatagtt tttggtgcag caaactttac tatgcctata tctttaaatt ctgtgacaac
     2281 attggggtat gacccaattt ttatgggcgc tgcaacaata tctgatattg cagtttgtgg
     2341 tgcaatgttt ggatatttct taaaaactag gaataaagaa caaaaacaac tatttggtac
     2401 agtaagtttt agtgcactta tgggagttac agaaccttca gtgtttggtg tgtttatgaa
     2461 atatagaaga ccatttgtag cagtaatgat aggtggaggt ataggtggtt taatagcagg
     2521 tttagctcaa gttaaaacat atggaatggt ttggggatta gctgcattac caacgtatct
     2581 tgttggagga gaggtatcta actttacatt tatgataata agtgtagtag tatcatttgt
     2641 agcagcaaca gcagcttcct atttactagg aataccttca gatgaaaaag aagaagttaa
     2701 gggtgataat gaaaaagaat tagaactaat aatcaacgag aacaattcaa gaactattag
     2761 tattggaaat gttgcaaaag gtcaggtaat tgcacttggg gaagttaatg acaaagcatt
     2821 ttcctctgga gcattaggta aaggggttgg agttatacct agtgaatcaa aatcaactgt
     2881 tatatctcct gtagatggaa ctataactat agtatttcca actaaacatg catatggtat
     2941 agtgactgat gaaggattag aaatattaat tcatattggg atagatactg taaacttaga
     3001 tggaaaattc tttgaaagtc ttgtaacaca aaatcaaagg gttaaaaaag gagatgcttt
     3061 agcagtattt gaatctgata aaattataga ggaaggcttt gattctacta taataactgt
     3121 agttacaaat actagcgatt atttagatgt aatctcatca aatgatgaat cagaagaatt
     3181 attaactgta atagtataaa ttttaggagg gaaaattcat gaatattaaa gatacatttt
     3241 tctggggagg aagtattgca gcccatcaat gtgaaggttc atgggatagt gataacaaag
     3301 gacctgcaat tatggacttt gtaactaagg gctcttatga aacgccaaga gtaattactg
     3361 ataaaataga agaaaaatta gattatccat ctcataatgg aatagatttt tataatagat
     3421 ataaagaaga tatagcttta tttaaagaaa tgggatttag tgcattaaga atatctatag
     3481 attggtcaag aatttttcca aatggagatg atgaaaatcc taatgaatta gggattaaat
     3541 actatgaagg tctgatagat acattaatag aaaataatat agaacctatt gtaacactat
     3601 atcattttga attacctatg aatttagtac ataaatatgg ttcatggaat aacagaaaac
     3661 ttatagattt gtatttaaag tacagtgaga ctgtaataag aagatttgat gataaggtaa
     3721 agtactgggt tacatttaat gagatgaacc atattgaccc tcaaacagag cactcggata
     3781 tttttactta tatgatagca ggtattaagt atagtgaaat agaaaataag gttcaaacat
     3841 tggcaaatgt agggtataat atgactttgg cgggtgtaaa ggttgcaaag ttggctagag
     3901 aaatcaatcc caacaataaa attggatgtg tatttggact aaatccaatt tatccataca
     3961 attgtaatcc tagtaatgtg ttaaatgcat ttttagataa tgaccgtgat tattatcaaa
     4021 ttgatgcaat gtgcaatggg aagtttccac aatataaatt aaaagaatat gaaaaaaata
     4081 atataactat tgaagtgact gatgaagaca aaaaagcatt taaagaaggt aagttagatt
     4141 ttataggact taattattat ttttcaagtg tatctactcc aaaagaaaat ttatcaggtg
     4201 ataaatcttt atttggtggg attcaaaatc catatttgga acaaagtaag tgggggtggg
     4261 caatagaccc tataggttta agatttacct tgaactatat ttacagaaag tatcaattac
     4321 ctatcttaat tacagaaaat ggtttagggg catatgataa aatcgaagaa gatggaacta
     4381 taaatgatga ttatagaatt gaatatttaa gtaagcatct atctcaaatg aagtctgcaa
     4441 ttgaagaaga taatgttgaa tgttttggat atttgatgtg gggaccaatt gatttagtca
     4501 gtgcaactac aggtcagatg agtaagagat atggatttat ctatgttgac ttagatgatg
     4561 aaggcaaagg aagttttaag agatataaga aaaaatcatt tgattggtac aaagaagtaa
     4621 taaaatctaa tggagaagtt ttagattttt ctacggatat agtagtaggg taggaataag
     4681 ataaatagaa gttaggaact aatgttaatt agtgtctagt aaagcattta aaatagagta
     4741 tagggtcttt aaagtaaagt gtgtattctt cttaaaaata atggcaatta aaattactat
     4801 aaaaaggaga atacacattt tttattttta tacttaagta aatatttaga catattcata
     4861 gtataattta ctcattatat aaaaatagta tgatttactc actatataac tttataaatt
     4921 ttctggaaaa atgtcagaat atattgacaa a
//
LOCUS       DAJMZY010000173         4900 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.178, whole genome shotgun sequence.
ACCESSION   DAJMZY010000173 DAJMZY010000000
VERSION     DAJMZY010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4900)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4900)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4900
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.178"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            complement(984..1202)
                     /locus_tag="OE968_003611"
     CDS             complement(984..1202)
                     /locus_tag="OE968_003611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCP7220842.1"
                     /translation="MSVLLKTKIKSYREKNLMTQGELAKSVGVRRETIVHLENGRYNP
                     SLKLAMDIAKVFDTTVEELFEFIEENNI"
     gene            complement(1203..1610)
                     /locus_tag="OE968_003612"
     CDS             complement(1203..1610)
                     /locus_tag="OE968_003612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220843.1"
                     /translation="MSKQQTGIKSTLISEILGISYCIGATLVNKYFFKGSSIEYLPII
                     IWVLAMGAQWVYNKKYDDLIDEASKCILSRVNDIAIKVLFFSVAIVSIFLVTLDINVS
                     NLNIGMSLLVILFIQSLLKLILFIYFDRKGIYN"
     gene            complement(1696..2184)
                     /locus_tag="OE968_003613"
     CDS             complement(1696..2184)
                     /locus_tag="OE968_003613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3841 domain-containing protein"
                     /protein_id="HCP7220844.1"
                     /translation="MKFYTIQTLEFWNNNKNNKYLSNDYSFILEDFDIPYKWMYSQMT
                     NRIYEFDDSMIWVWTKRPDLRCSGYLEKGKKGVLLEIEISEDNVLLSEFDLWHLPLMD
                     ITVELYEDEQIEKKVSWERIFDLELCSKLNEVNIEDLTLQGVTSKVPLSNVKLIKEFV
                     AK"
     gene            complement(2389..3510)
                     /locus_tag="OE968_003614"
     CDS             complement(2389..3510)
                     /locus_tag="OE968_003614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HCP7220845.1"
                     /translation="MKEKLEEKSKIIKTSKEYKRTIIEEKDREWTQKLNDILSRGDFS
                     NEKLDKIKDLIPKEILTSENVGEVVTEDGYAKPEYDEVFKSLFTLNNDYDLLANFIND
                     ILKDAPYANRNIKQFTQIKRIIKVETDPTINYIGEKRPRLDILAEDEERNHINIEMQR
                     ALEEDYLERAEYYLSRVHGRKLEEGKEYKEIGKTVGIHILNHVKYNHIEDYVNCLRLT
                     MDGHPDIFSSKTALYFIELPKIRKSSCIANRVLIWGKLIDNPSHIDIRILSKTDYVIK
                     RALDRLKELGSNEDYLLNLKRGAYIMNKSRNFKEEIFQEGIEKGIEKGIEKGIAKGKR
                     EEKFNIIIKLKNKGYNLSEICDIIDDLNKSEVEKVYNQN"
     gene            complement(3883..4053)
                     /locus_tag="OE968_003615"
     CDS             complement(3883..4053)
                     /locus_tag="OE968_003615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220846.1"
                     /translation="MDSNNNTIKSTVKKGISFGSCLAMIISYTAWKSIPWAIFHGLMS
                     WIYVLYYWVKYA"
     gene            complement(4225..4668)
                     /locus_tag="OE968_003616"
     CDS             complement(4225..4668)
                     /locus_tag="OE968_003616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCP7220847.1"
                     /translation="MIEIKTIEINKKSQIDLLILADPCEEMIDKYLNKGTMYALYDNK
                     ELTCIAVVNEISKEICELKNIATYEHFQNMGYASKMIYHLLDVYSKKYSSMVVGTSES
                     GVPFYEKFGFVYSHKIKNFFVDNYPEPIFEGELQCVDMLYLSYNF"
BASE COUNT         1637 a          780 c          420 g         2063 t
ORIGIN      
        1 aagtatattt ggaagtaatt tcatatttat ttaacttaat ttttttgtga taaaataatt
       61 ctaattttca tatagatatt attataaatt ttctagttta tggagttatt cattctataa
      121 ttcacaaata tgtatttttt aatctattaa actattcatt ttctggctta taagcatgga
      181 cttcttatct ataagcttgg tttttcatct aataagttat ttattcttta atctatgagc
      241 ttgatttttc atctataagt catttatttt ttaatctata agtttagttc ttcatctata
      301 aatcatttat tttttaatct ataagtttgg tttttcatct ataaataagt catttatttt
      361 ttaatctata agtttagttc ttcatctata aatcattcat tttttaatct ataagcttgg
      421 tttttaccta taattaattc attctctaat ctataagctt ggtttttatt tataagtcat
      481 ttattctcta atctataagc ttggttttta tttataagtc atttattctc taatctataa
      541 gcttacttct taatctataa gtcatttatt ctctaatcta taagcttact tcttaatcta
      601 taaatcattc attttttaat ctattagctt gttttttacc tataattaat tcattctcta
      661 atctataagc tttctttttc atctataaat cattcattct ttaatctatg agcttggttt
      721 ttcatctata agtcatttat tctctaatct ataagctttc tttttcatct ataaatcatt
      781 cattctttaa tccattagct tggtttttca tctataagtc atttattctc taatctataa
      841 gcttacttct taatctataa atcattcact ctttaatcca ttagcttggt ttttcatcta
      901 taagtcattt attctctaat ctataagctt ggttttttac ctataattaa ttcattctct
      961 aatgcataag taatacatga aatttaaata ttattttctt caataaattc aaacaactct
     1021 tctacagttg tatcaaatac cttagcaata tccattgcca gttttaaaga aggattgtag
     1081 cgaccatttt ctaaatgtac aatagtttca cgtcttactc ctactgactt tgcaagttca
     1141 ccttgtgtca taaggttctt ttctctatag gatttaattt ttgtctttag taatactgac
     1201 acctaattgt atatcccctt tctgtcaaaa tatataaata gaattaactt caacaaggat
     1261 tgaataaaca aaatgactaa taaagacatt cctatattta aatttgacac atttatgtcc
     1321 aaagttacaa gaaatataga tactatagct acagaaaaaa acaatacttt tattgcaata
     1381 tcattaactc ttgatagtat acattttgat gcctcatcaa ttaaatcatc atacttttta
     1441 ttatagaccc actgagctcc catagctaat acccaaataa ttataggaag atattcaata
     1501 ctacttcctt taaaaaaata cttatttact aatgtagctc caatacaata agaaattccc
     1561 aatatttctg aaataagtgt tgatttaata ccagtttgtt gtttagacat ataaaatccc
     1621 ccttaaaaag ttatgtattt ataacacctc ttgttataaa tatataactt ttttgaataa
     1681 atttcaataa aaatattatt ttgcaacaaa ttcttttatt aattttacat tagatagagg
     1741 cactttagat gtcactcctt gcaatgtcaa atcttctata ttaacttcat ttaattttga
     1801 acacagttct aagtcaaata ttctttccca acttaccttc ttttcaattt gttcatcttc
     1861 ataaagctct acagtaatat ccattaaagg taaatgccat aaatcaaatt ctgataataa
     1921 cacattgtct tcacttattt ctatttcaag taaaacacct ttttttcctt tttctaaata
     1981 accactacat cttaaatcag gtctcttcgt ccaaacccat atcatactat catcaaattc
     2041 atatattcta tttgtcattt gactatacat ccatttgtat ggaatatcaa agtcttctaa
     2101 tataaaagaa taatcatttg atagatattt attgttttta ttgttattcc aaaattctaa
     2161 agtctgtata gtataaaatt tcatatataa atcaacccct ttgtttttct ataagaagga
     2221 gatggttcaa acttttattt tgaattatct cctttattta tacacctctt tgtacctatt
     2281 atttatatat ctctttatat ctaccatatt taaataacaa agttttatat taatttaaat
     2341 ttaaaagagg aagctttgta tttatctagt gccatctcaa tcatagtatt agttttgatt
     2401 atagactttt tcaacctctg atttattcaa atcatctata atatcgcata tttcactcaa
     2461 attgtatcct ttatttttta attttatgat gatattaaat ttctcttctc ttttcccttt
     2521 tgcaatacct ttttcgatac ctttttcgat acctttttca ataccttctt gaaaaatttc
     2581 ttctttaaaa tttctacttt tattcataat atacgcacct ctctttaaat ttaataaata
     2641 gtcctcatta ctacctaatt cttttaatct atcaagtgct cttttaataa cataatccgt
     2701 tttagatagt attctaatat ctatatgaga aggattatca ataagtttac cccatattag
     2761 aactctgttt gctatacaac tggatttacg aatttttgga agttctataa aatataatgc
     2821 agttttacta gaaaaaatat ctggatgccc gtccattgtt aatctcaggc aatttacata
     2881 atcttctatg tgattatatt ttacatgatt tagtatatgt attccaacag tttttccaat
     2941 ttctttatat tctttacctt cttctaactt tctaccatgt acacgactaa gataatattc
     3001 agctctttcc aaataatcct cttcaagagc tctttgcatc tcaatattta tatggttacg
     3061 ttcttcatct tcagccaaaa tatcaagtct aggtcttttc tcaccaatgt aattaattgt
     3121 tgggtcggtt tcaaccttaa ttattctttt tatttgagtg aactgtttga tattcctatt
     3181 agcatatgga gcatctttga ggatatcatt tataaaattt gcaagtaaat cgtaatcatt
     3241 atttaaagta aacaatgatt taaatacctc atcatactca ggcttagcat acccatcttc
     3301 agttacaact tctccaacat tttcactagt caatatttct tttggaatta aatccttgat
     3361 tttatctaat ttttcattag aaaaatcacc tctactaagt atgtcattta atttttgggt
     3421 ccattctctg tccttttctt caattatagt tcgtttatac tcttttgatg ttttaataat
     3481 cttagatttt tcttctaatt tttctttcat atcaacacct cttttttatt attacccatt
     3541 tcttcatacc aaagtctgaa cttctaagta aaatttgcat tattgaaata agaaccttat
     3601 aaacttatat atcattacta aagttaagac tttaaagaga agcacttaga ttacaataga
     3661 ttttagatag ctttcttttt aaaactattg ttgataaatg aatgaatata agggtatgta
     3721 ttaaaataga gatactcatc tttttcattg tttaagtaat gaaaatatat tttatttaat
     3781 acaaaaaaga gtgccttata aactaaaagt tcacttcgag acactccctt acattttgtt
     3841 tcttaaactt tacaatatta catacttatt tattaattta atctatgcat acttaaccca
     3901 ataataaagt acatatatcc aactcattaa gccatgaaaa atagcccatg gaatagattt
     3961 ccatgcagta taagaaataa tcattgctaa acaagaacca aaagaaatac cctttttaac
     4021 agttgatttt atagtattat tatttgaatc cataattaat cctccaaaat tcaaaataaa
     4081 caagttatta tatatcttat ttgaatctaa tacaatataa cagcttctaa ataaattata
     4141 ctcttattat acataattta taaattataa ttccgataat tatatgaatt aattaattat
     4201 attaacctaa aaatattatc ctatctaaaa gttatatgat agatacaaca tgtcaacaca
     4261 ttgtaattct ccttcaaaga ttggttctgg ataattatct acaaaaaagt ttttaatttt
     4321 atgtgaataa acaaatccaa acttctcata aaaaggaact ccactttcag atgtaccaac
     4381 aaccattgat gaatattttt tactataaac atctaaaaga tgataaatca tctttgaggc
     4441 ataacccata ttttgaaaat gctcatatgt agcaatgttt tttaattcac atatttcttt
     4501 ggaaatttca tttacaactg ctatacaagt aagttcttta ttatcataca atgcgtacat
     4561 agttccttta ttgagatatt tatcaatcat ttcttcacat gggtcagcta atattaaaag
     4621 gtcaatttga ctttttttat ttatttctat agtttttatt tctatcataa gttctccacc
     4681 ctcactttat tcaaacctta atttaacaaa cttcttacag tacttattta gttcattttg
     4741 atatatattt ttacttttta aaatatagtg ataattccct agaatattaa tattaataat
     4801 aaattataat atcagctcta gcaattacct agaatatcaa tactaatatt catctataat
     4861 attagttcta gcaattacct agaatatcaa tattaatatt
//
LOCUS       DAJMZY010000174         4829 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.179, whole genome shotgun sequence.
ACCESSION   DAJMZY010000174 DAJMZY010000000
VERSION     DAJMZY010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4829)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4829)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4829
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.179"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            44..339
                     /locus_tag="OE968_003617"
                     /pseudo
     CDS             44..339
                     /locus_tag="OE968_003617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427875.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            747..1436
                     /locus_tag="OE968_003618"
     CDS             747..1436
                     /locus_tag="OE968_003618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCP7220848.1"
                     /translation="MDILLVEDDKNIREMVYDFLISENYSVKTAIDGNTAIEIFKNYS
                     FDIILLDLMLPKSSGFEVLKYIRSVSVVPVIITTAKDSDTDKMLGLNLGADDYITKPF
                     SIVELLARIKANIRRATVYSSSRNSQDMVIRYKDLIINISKYVVSKNGIDLNLTHTEF
                     EIVKLLATNQGRAFSKEQLYNAIWKEPYYGNENVLNTHINRLRNKLSDGIEKNNYIKT
                     LWGIGYKMEEE"
     gene            1436..2353
                     /locus_tag="OE968_003619"
     CDS             1436..2353
                     /locus_tag="OE968_003619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HCP7220849.1"
                     /translation="MELFLVVISIVLFALYLKERNKSKKMESDYKYINSRLRDITNDD
                     EINYILVPSDISIVKETAVDINKLVEKFYSRQINYNRSEKAILQIFTNISHDLRTPIT
                     VLKGYIEMLYLQSQKEELSSSMRAIVEKMQTNSNELVNSINNLFNMAKIQSGDMILNL
                     QKSNLTQLCHEIILEFYDLLDKENFNVEVNIEDRPIYANVDTEALQRILKNLIDNAIK
                     YGSDGRFLGISLYEKEKHVFIDIEDKGSGISETEKEHIFTRAYTADRKKGNGLGLAIS
                     QGLANSMGGSIYVNSRPNVKTVFTVKLKS"
     gene            2426..3352
                     /locus_tag="OE968_003620"
     CDS             2426..3352
                     /locus_tag="OE968_003620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCP7220850.1"
                     /translation="MNYIIETHQLKKIYKDKAVVNAVNIHVKKGEIYGFVGPNGAGKS
                     TVMKMLLNLVNPNSGEIVMFGKKVAETDFEILKKIGTIIENPYLYENLTAKQNLDLHC
                     EYMGYYNKEHISEVLECVGLSKQSNKKVSKYSLGMKQRLAIARAILTKPELLILDEPI
                     NALDPEGIREMRELFRKLNTDYGITIFISSHILSEVEQIADTIGIIQDGKLIKEISMS
                     DIHKYQTDYVEVDVDNVELAGYLLEKEFGIKDFKITSESCIEIYDLRKDVKEISKIFI
                     QNQIGINSIGRKQSSLEDYFFQTTGTGGKETL"
     gene            3349..4029
                     /locus_tag="OE968_003621"
     CDS             3349..4029
                     /locus_tag="OE968_003621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCP7220851.1"
                     /translation="MIHLMKLELKKVGLKRYFLFSMLGIFLCMFFVFTGLNDKSTSIY
                     DYDVTFRTISLFFCFYYIILFAVLNVAYIINEYTNKTILILFSYPLDRKKLILSKLLL
                     ITTLMISSMIVGYICCFTFVVVLDKYFNLVIGDFHISILSYWIPGAIKSIIVFCSLGI
                     WTFVVGMIRKSIPVTLVSSIIFINLRQFILAGTNTTQDSLISVFIIVGITVIGIYYIL
                     NHKVTEID"
     gene            4127..4462
                     /locus_tag="OE968_003622"
                     /pseudo
     CDS             4127..4462
                     /locus_tag="OE968_003622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427885.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
BASE COUNT         1826 a          503 c          779 g         1721 t
ORIGIN      
        1 tatttttata gtagtagtta attattaata aggaggggtc aaaatgccta gcatgattat
       61 ggaagttgta ggagtactat ttatagctat tggattaatc ttgacattca ttgaaataaa
      121 aggaaatttc ccttcttttt atggttttgg tcaaaattaa aatgctgtag gtattatagc
      181 agcaggaatt gctttaattt tctttagaaa tggcatagat acatagattc tatagctact
      241 tatggtgtat ttttagcaat agaacttgtt gtaatagttg catatttctt aataagaaaa
      301 aaatttacta aagaagataa acatttaaga actaattaac taaattatct actataaaat
      361 tggaaaatta aaaacaaata aaagtttgtt tttaattatt taaaatccaa atttgattat
      421 ttttaaagaa actatgttct gtataaaact agaatgtggt ttctttttta tgtataaaat
      481 attttttagc aaaagttaaa aggtgtttta taatataaaa tagttaattg tagatgttaa
      541 taaaagaaaa ttatgtatat tttagataaa gataagagag tatactatat tttaattctt
      601 ttttcaataa agcttattga aaagaacttt aacttagaag agtatcacca aattgcagat
      661 acaatatcat aagcagttat ttattgacaa ccctttttaa taaatatatc atttgaagta
      721 tactgacgaa aaggagttga ataataatgg acatcttatt ggttgaagat gataagaata
      781 ttcgagaaat ggtatacgat tttctgatta gtgagaatta ctctgttaaa actgccattg
      841 atggaaatac agctattgaa atatttaaaa attattcatt tgatattatt ttactggact
      901 tgatgttacc aaagtctagt ggttttgaag tattaaaata tatacgaagt gtgagtgttg
      961 ttcctgttat tattactact gcgaaagata gtgacacaga taaaatgcta gggcttaatc
     1021 taggtgcaga tgattatatt acaaagcctt tttcaatcgt agaattgctt gcaagaatta
     1081 aagctaatat tagacgtgca acagtgtata gcagttcaag aaactctcaa gatatggtta
     1141 ttcggtataa ggatttgatt ataaacatat caaaatatgt agtttcaaag aatggaattg
     1201 acttaaactt aacacataca gaatttgaaa ttgttaaatt actagcgact aatcaaggac
     1261 gtgctttttc aaaggaacaa ttatacaacg ctatttggaa agaaccttat tatggaaatg
     1321 aaaatgtgct aaatactcat attaacaggt taagaaataa attgtctgat ggtatagaaa
     1381 aaaataatta tattaaaact ctttggggaa ttggctacaa aatggaggaa gaataatgga
     1441 gttattttta gttgtaattt cgattgtact atttgctctc tacttaaaag aacgaaataa
     1501 atcaaagaaa atggaaagtg attataagta tatcaattca agacttcgtg acataacaaa
     1561 tgatgatgaa attaattata ttttagtacc atctgatatt tcgattgtaa aagaaacagc
     1621 agtagatata aataaacttg ttgaaaagtt ttacagcagg caaattaatt ataatagaag
     1681 tgaaaaagcg atattgcaaa tatttacaaa catatcacac gatttacgaa ctcccatcac
     1741 agtattaaag ggttatattg aaatgctata tcttcaaagt caaaaagaag aattatcttc
     1801 ttcaatgaga gcaattgtgg aaaaaatgca aacaaattca aatgagcttg ttaattcaat
     1861 aaataacctg tttaatatgg caaaaatcca atctggagat atgatattaa atcttcaaaa
     1921 atccaatcta acacaattat gtcatgagat tattttagag ttttatgatt tgctagataa
     1981 agaaaacttt aatgttgaag ttaatattga agatagacct atatatgcaa atgttgacac
     2041 agaagcatta caacgtatac tcaaaaattt aattgataat gctataaaat atggttcaga
     2101 tggtagattt ttagggattt cactatatga aaaggaaaaa catgttttta tagatattga
     2161 ggataaaggt tcaggtattt ctgaaactga aaaagagcat attttcacaa gagcttatac
     2221 tgctgacaga aaaaaaggca atggtttagg tttggctatt tctcaagggc ttgcaaactc
     2281 tatgggaggt tcaatttatg taaatagtag acctaatgta aaaacagttt ttacggtaaa
     2341 attgaaaagt tagaaaaaag ttagatttaa aagagagaaa agacaatttt attttgtata
     2401 ctgtttttag aaaggaggga gtatgatgaa ctatatcata gagacccatc aattaaagaa
     2461 aatatataaa gataaagctg ttgttaatgc tgttaatatt catgtgaaaa agggagaaat
     2521 ttatggattt gttggaccaa acggggcagg taaaagtaca gtaatgaaaa tgttgctaaa
     2581 tcttgttaat ccaaattctg gagaaatagt tatgttcggt aagaaagtgg cagaaactga
     2641 ttttgaaata ttaaaaaaga ttggtactat tattgaaaat ccgtatttat atgagaattt
     2701 gactgctaaa cagaatcttg atttacactg tgaatatatg ggttattata acaaagaaca
     2761 tatatcagag gtattggaat gtgtcggatt gtcaaagcaa tcaaacaaga aagtttcaaa
     2821 atattcttta gggatgaaac aacgtcttgc aatagctaga gcaattctta ctaaaccaga
     2881 attattgatt cttgatgaac ctataaatgc actcgaccca gaggggataa gagaaatgcg
     2941 agaattattc cgtaagttaa atacagatta tggaataact atatttattt ctagtcatat
     3001 tctttcagag gtagaacaaa ttgcggacac tattggaatt attcaagatg gtaaacttat
     3061 taaagaaatt tctatgtcag atatacacaa atatcaaaca gattatgttg aagtagatgt
     3121 agataatgtg gagcttgctg gatacttgtt agaaaaagaa tttggaataa aagactttaa
     3181 aattacttcg gaaagttgta ttgaaatata tgatttacga aaagatgtaa aagaaatatc
     3241 caaaatattt attcaaaatc aaattggtat aaatagcatt ggacgtaaac aaagttcttt
     3301 agaagattac ttcttccaaa ctacaggtac aggaggtaaa gaaacactat gatacattta
     3361 atgaaactag agctaaaaaa agttgggcta aaaagatatt ttttattttc aatgctgggg
     3421 attttcttat gtatgttttt tgtctttact ggattgaatg ataaatctac ttcaatatat
     3481 gattatgatg ttacatttag gacaatcagt ttatttttct gtttttacta tattatatta
     3541 tttgctgtgt tgaatgtggc atatataata aatgaatata caaataaaac aatcttgatt
     3601 ttattctctt atccacttga ccgtaaaaaa cttattttat caaagttact tttgattacg
     3661 actcttatga tatcatcaat gatagttgga tatatctgtt gttttacatt cgttgttgtg
     3721 ttggataagt attttaattt agttattgga gattttcata tttcaatttt atcttattgg
     3781 ataccaggag caattaaaag tattattgta ttttgctcat taggtatatg gacattcgtt
     3841 gttggaatga taagaaaatc aatacctgtt acccttgtca gttcaattat ttttatcaat
     3901 ttaagacaat ttattttagc tggtacaaat acaactcaag acagtttgat ttctgttttt
     3961 attatagttg gtataactgt gattggtata tattatatac taaatcataa agttactgaa
     4021 attgactaga tactgtggat aggagggtag ttattaattg tatcttcttg ggataataat
     4081 gatttgctat tatatcagct attattaata ttattagagt tttaataata ttgcacaacc
     4141 atttgaagtt gagccaaagc ttgatgaatt aattgaatgg tactatagtc agagtgaagt
     4201 atctattaaa gttatagctg aatttcatta tagatttgaa ttgatacatc catttcaaga
     4261 tggtaatggt cgcataggta gatttgttat gctaaaacag atgttagaaa ataatcttcc
     4321 tataaaaatt gtatcttggg atagtgagga attgtataga aactccttaa attcttgtag
     4381 tttaggtaat tatgtccctt taattgaata tttatcaagt ttagaagatt ttagagaagt
     4441 atataaaatg ttatggaaat aattgtttgc agcaaaaaaa gtttttatat aaatatattt
     4501 ttatctatgc tatttaacgc taatttctta gttattctta gcttggacta tacccactat
     4561 tttaactata taaaatagtg gatatagttt aactatctct ttataactat ttttatgtat
     4621 cttagttgtt tcttaatatg gggacagttc ataaaactaa aagtgatttt taattttatc
     4681 atttataatt taccattaca tcagaaaaat gcttatcatt agaattttca taaaaggtac
     4741 ctattttttt caattaactg aatcaattct attagtctta atctttcata tttcaaattg
     4801 ataatataag aaaataaaaa ataaaaaat
//
LOCUS       DAJMZY010000175         4764 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.180, whole genome shotgun sequence.
ACCESSION   DAJMZY010000175 DAJMZY010000000
VERSION     DAJMZY010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4764)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4764)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4764
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.180"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            <1..183
                     /locus_tag="OE968_003623"
     CDS             <1..183
                     /locus_tag="OE968_003623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HCP7220852.1"
                     /translation="VSQMRFFDKVESKNLYTFNIYTNLLIVLNDDSYNELREEPIFKD
                     VIEKILDMEKMLKNKE"
     gene            complement(603..1124)
                     /locus_tag="OE968_003624"
     CDS             complement(603..1124)
                     /locus_tag="OE968_003624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCP7220853.1"
                     /translation="MKFKRLRTSENKLCYKAMELYKISFPFHEQRKSSLQEEILKNKE
                     YQFNLIYDKNQFVGIILCWETDDFIYVEHFCIFPEMRNNRYGQRALELLNKKGKTIIL
                     EIDLPIDEISIYRKAFYERVKYKTNNYEHIHPPYHEKFNGHNLIVMSYPEKLSKMEYD
                     KFNHYLRNNVMSF"
     gene            1480..2277
                     /locus_tag="OE968_003625"
     CDS             1480..2277
                     /locus_tag="OE968_003625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HCP7220854.1"
                     /translation="MEKREKRIIISSLLSVSILMGLVSIYSILNKEDIILTVKGQEQK
                     VSSFKKTVEELLDEQGIKYNSEDKINPSLDTELKDDMKIKVVKVTKSKKEEIEKIPFD
                     TKHVNDSNLLKGKSKVYQEGQEGEKKLVYNLTYHDGKLVKKVLSKEVISKEPTTKIIK
                     YGTKEKVLIASRGANIRGGKHMKVVATAYAGDTITSTGTTPRWGVIAVDPRVIPYGTK
                     VYIPKLGMTFVAEDCGGAIKGNRIDIFMNSEGKASNWGRKSIDIYLH"
     gene            2387..2977
                     /locus_tag="OE968_003626"
     CDS             2387..2977
                     /locus_tag="OE968_003626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HCP7220855.1"
                     /translation="MKIVCLGDSLTYGFGVSRSNSWTNIVNKETRLEIVNKGINGDTT
                     SGMLARFNEDVVKNSPDIVFIMGGTNDFIAGAGNEIINSNIMAMVHQSYSKNIIPIIG
                     IPLKPDIPNVREDWSCFTDFNIVSQNLESYSYWIKKFCMTFNTNFVDFYSEYNKNMEL
                     EGYKKLYFDGLHPTKEGHRIMADIFINSINKYIEEL"
     gene            3043..4740
                     /locus_tag="OE968_003627"
     CDS             3043..4740
                     /locus_tag="OE968_003627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HCP7220856.1"
                     /translation="MDYTKTYEEWIKGSYFDEDTKLELENIKNNEKEIEDRFYKDLEF
                     GTAGLRGIIEAGTNRINKYTVRRATFGLANYILENTTKEETSRGVVIAHDNRHKSRQF
                     CIESANTLAACGIKAYIFDSLRTTPELSFAVRSLNAIAGIVITASHNPPEYNGYKVYW
                     EDGAQVMPEIANAITEKVNSIHDYSTIPTLTEANKNLVVLLDESQDTKFIEAVKSQII
                     RKDLVKNVGKSFKIVYTPLCGTGNVPIRRALKEVGFENIIVVPEEENPDPNFAGLDYP
                     NPEEKKALNRGILLAKEKGADLVIATDPDCDRVGVAVKTTTGEYALLTGNQIGGMLTH
                     YIIEGLKENNKLKENPTIIKTIVTSEFGADIAKANNVDVLNVLTGFKFIGEKIKLFEQ
                     NKNRSYVFGYEESYGYLVGTHARDKDGVVSSLLISEMAAFYYSKGMSLYDGLIELYKK
                     YGFFKEQTISLTLKGIEGVEKIKEIISYFRENQIDYINSIKVVDKKDYKNGIDNLPKS
                     DVLKYFLEDESWVAIRPSGTEPKLKFYIAVKGASDIEADKKIQGLKKYIDDMVEKLK"
BASE COUNT         1926 a          491 c          805 g         1542 t
ORIGIN      
        1 gtaagtcaaa tgagattttt tgataaggta gagtctaaaa atttatatac ttttaatata
       61 tatacaaact tgttaattgt acttaatgat gatagttata atgagcttag agaagaacca
      121 atttttaagg atgtaattga aaagatttta gatatggaaa aaatgttgaa aaataaagaa
      181 taagtaaaaa tttaatatag gacttaaaga ttaatcaaat taaaagaaag tgtttcaaaa
      241 taaaaatttg aatcaccttt tttgtcggtc ttaaacagtt atttagaaaa atagaggttt
      301 caaaatagaa atctgaatta tctgtattat tacacaaaaa tagaaaccta aatttataaa
      361 aatagaataa agtttgttat ataaaatgta attttgtcta taaaatctca cttgttttct
      421 taactttaag cgtgaaaaag agaatgtatc atgaattttt tagttcatga tgcatccttc
      481 tttgtatgaa atccaatata tctttattat ttaaacaatg gaaaagagcc ttatttctat
      541 tttgagacat ctcttttatt taattatgaa gttttataca gttcaataaa taggaattat
      601 atttagaaac tcatgacatt atttcttaga tagtgattaa atttatcata ttccatttta
      661 gataactttt ctgggtaaga cattacaatc aggttatgcc cattaaattt ttcatggtat
      721 ggtggatgaa tgtgttcata attatttgtc ttatatttta ctctttcata gaacgccttg
      781 cgataaattg aaatctcatc aattggaagg tcaatttcta aaataatagt ttttcctttc
      841 ttatttaaaa gctctaacgc tctttgtcca tatctattat tgcgcatttc tggaaaaatg
      901 cagaaatgtt ctacatagat aaagtcatct gtttcccaac ataaaattat gccgacaaac
      961 tggtttttat cataaattaa attgaactga tattctttat ttttcaaaat ttcttcttgc
     1021 aaagaagatt ttctttgttc atgaaatggg aaactaattt tatataattc catagccttg
     1081 taacataatt tattttcact ggttcttaac cgtttaaatt tcactttact cctcctaatc
     1141 acgaaaattc caatttattt atgagttcat tttaccatag tcagtatttg catacaatgt
     1201 gttttaagtt gagtgtcatt tctttctttt atttatgctt atatctcata gactaagaga
     1261 taattgctta agacataact aaaaactatt atattaagct ttgataatct aaaaacagta
     1321 tatttatgga cttttctagg tctaaaagta atcttaataa ttttagaagt tacaaaaaag
     1381 ttacataaat ttggaaagct ataatataca tatataatat aaggttaaaa ctgtaatgaa
     1441 taatattaat ttaaaatttg aacatggaag gagattatta tggagaaaag agaaaagagg
     1501 ataataatat catctttatt aagtgtatca attttaatgg gtttggtaag tatatattct
     1561 atattaaata aagaagacat aattttaact gttaagggtc aagagcaaaa agtatcttcc
     1621 tttaagaaaa cagttgagga acttttggat gaacagggta taaagtataa ttctgaagat
     1681 aagattaatc caagtttaga tacagaacta aaagatgata tgaaaataaa agttgttaag
     1741 gtaactaaaa gtaaaaaaga agagattgaa aaaattccat ttgatacaaa gcatgtaaat
     1801 gatagtaatt tgttaaaagg aaaatctaaa gtttatcaag aaggtcaaga aggagaaaaa
     1861 aaactagtct ataatttaac ttaccatgat ggaaagttag tcaaaaaagt cttatcaaaa
     1921 gaagtaatat ctaaggagcc aactacaaaa attataaaat atggaactaa agaaaaagta
     1981 ctaatagcat caagaggagc aaatataaga ggaggcaaac atatgaaagt ggttgccact
     2041 gcatatgcag gagatacaat aacatctact ggtacaactc caagatgggg tgttattgca
     2101 gttgacccac gtgtaatacc atatggaaca aaagtatata tacctaaact gggtatgact
     2161 tttgtagcag aagattgtgg aggtgcaatt aaaggtaata gaatagacat ttttatgaac
     2221 agtgaaggaa aagcttcaaa ttggggaagg aaaagtatag atatatatct acattaaatt
     2281 agtgaataga ataactttac ttgaaggaca aaaaagtata aaatatgaat taactaaact
     2341 gttagattat tcttaaaaca taaaaatata tctaaggggg gataagatga aaatagtatg
     2401 cttaggagac agtttaacgt atggatttgg agtatcacga agtaattcat ggacaaacat
     2461 tgtaaataaa gagactcgat tagaaatagt aaataagggt ataaatggtg atacaacaag
     2521 tggtatgtta gctaggttta atgaagatgt tgtaaaaaat tctcctgata tagtttttat
     2581 aatgggtggc accaatgatt ttattgctgg tgcgggaaat gaaattatta attctaatat
     2641 aatggctatg gtgcatcagt catattcaaa aaatattata cctataatag gtataccatt
     2701 aaaaccagat attccaaatg ttagggaaga ttggagttgt tttactgatt ttaatatagt
     2761 atctcaaaac ttagaatcat atagttattg gataaaaaaa ttttgtatga catttaatac
     2821 taatttcgta gatttttatt cagaatataa taaaaatatg gaactagaag gatataaaaa
     2881 attatatttt gatgggttac atccaaccaa agagggtcat agaataatgg cagacatttt
     2941 tattaattca attaataagt atatagaaga gttatagatt acattaaaat gcttgtttat
     3001 gcgtcagttg caataaatac atacagtaga gaggggttta ttatggatta tactaaaact
     3061 tatgaagagt ggataaaggg ttcatatttt gatgaagata caaagctaga gttggagaat
     3121 ataaaaaata atgaaaaaga aatagaggat agattctata aggatttaga atttgggact
     3181 gcgggtctta gaggaataat tgaagcagga acgaatagaa taaataagta cacagttaga
     3241 agagctactt ttggattggc aaactatata ttagaaaaca caacaaaaga agaaacaagt
     3301 agaggagtag taatagctca tgataataga cacaagtcta gacaattctg tatagaatct
     3361 gcaaatactt tggcagcatg tggtataaaa gcatatatat ttgatagttt gagaactact
     3421 ccagaattat cttttgctgt tagaagctta aatgcaatcg ctggtatagt cataacagca
     3481 agccataatc ctccagaata taatggatat aaggtatact gggaagatgg agcacaagtt
     3541 atgccagaga ttgcaaatgc aataacagag aaagtaaata gtatacatga ttatagtaca
     3601 ataccaacct taacggaagc taataaaaat ttggtagttt tgttggacga atcacaagat
     3661 actaaattta tagaagcagt gaaaagccaa attataagaa aagatttagt taaaaatgta
     3721 ggtaaaagct ttaagatagt ttatacacct ctttgtggaa cagggaatgt tccaataaga
     3781 agagcattga aagaagttgg ttttgaaaat ataattgtag ttccagaaga agaaaatcca
     3841 gacccaaatt ttgcagggct tgattatcca aatccagaag agaaaaaagc tttaaataga
     3901 ggtatattac tcgcaaaaga aaaaggagca gaccttgtaa tagcaactga cccagattgt
     3961 gatagagtag gtgtagcagt aaaaactact acaggtgagt atgctttact tacaggaaat
     4021 caaattggtg gtatgctgac acattatata atagaaggat taaaagaaaa taataaatta
     4081 aaagaaaatc ctacaataat aaaaaccata gttacatcag aatttggagc agatatagct
     4141 aaagcaaata atgttgatgt attaaatgtt cttacaggtt ttaaatttat tggtgaaaaa
     4201 ataaaattat ttgaacaaaa taaaaataga agttatgtat ttggatatga agaaagttat
     4261 ggttacttag ttgggactca tgctagagat aaagatggtg tagtttcttc attgttaata
     4321 tctgaaatgg cagcatttta ctattcaaaa ggtatgagtt tatatgatgg tttaatagaa
     4381 ctttataaaa agtatggatt tttcaaagaa cagactatat ctttgacttt aaaaggtata
     4441 gaaggtgtag aaaagataaa agaaataata tcttatttta gagaaaatca aattgattat
     4501 ataaatagta ttaaagtagt tgataaaaaa gattataaaa atggtataga taatcttcct
     4561 aaatctgatg ttttaaaata ctttttggaa gatgaatctt gggtagctat aagaccatct
     4621 ggaacagaac caaaacttaa attttacata gctgtaaaag gagctagtga tattgaagca
     4681 gataaaaaga ttcaaggttt gaaaaagtat atagatgaca tggtcgaaaa attaaaataa
     4741 aatattatta ttttataaga taat
//
LOCUS       DAJMZY010000176         4721 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.181, whole genome shotgun sequence.
ACCESSION   DAJMZY010000176 DAJMZY010000000
VERSION     DAJMZY010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4721)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4721)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4721
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.181"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            142..1293
                     /locus_tag="OE968_003628"
     CDS             142..1293
                     /locus_tag="OE968_003628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HCP7220857.1"
                     /translation="MEIYLDNSATTKPYQEVIDKMVYALNTEYGNPSSVHRKGVEVEK
                     AIKEVRQDIAKSLGAKEKEIYFTSGGTECNNTIIRGITSLNKKRKNHIISTNIEHPSV
                     LNTLKDLEEDGFEVTYLEVGKDGKINIEDLKNAIKSTTCLVSMMHVNNEIGTIQPIGE
                     VGKYLKGLKEKIYFHVDAIQSYGKINFRLSKYNIDFMSVSAHKFHGPKGIGFMYIKEN
                     NRLKPMLTGGGQEIGIRSGTENVPGIYGLGEAVRILNKDLDVVISKVNNLKNILKNEI
                     IDNIEDIKINSPEDGVCHILNVSFRGTKGEVLLHYLEQKGIYVSTGSACSSKKKGSYV
                     LNAIGLTNEEINGTIRFSLSDMNTEEEMLEAVKVLKESICDLRSIMKRK"
     gene            1339..2514
                     /gene="thiI"
                     /locus_tag="OE968_003629"
     CDS             1339..2514
                     /gene="thiI"
                     /locus_tag="OE968_003629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HCP7220858.1"
                     /translation="MVYNILIVKYGEIGVKGKNRYIFENRLIRNIRNMLKPIGRFNVY
                     KEYGRIYVDLEDYDYEEVIEEVRKVFGIVGVCPGVRAKKDYDTLKEIALKMLEEKIEA
                     GYKTFKVESRRGDKSFGLTSQEMSMDIGGYLLSKVGDRINVDVRNPEVKIKCEYREFH
                     TMVYSDTIPGYGGLPLGTNGRAMSLLSGGIDSPVATWMVAKRGMEVEAVHFHSYPFTS
                     ERSQEKVKDLAKILAKYCGRVRLHKVNILEIQKAIGENCNEEEATILSRRFMMRIAQR
                     LSEKRHCDALITGESIGQVASQTIQGLTCTNAVVDLPVFRPLIAMDKSDIVDIAKKIG
                     TFETSILPEEDCCSVFSPRKPVTKPRLEKIEKSETALDIEKLVQDAIDKIEVEDIEF"
     gene            2670..3473
                     /locus_tag="OE968_003630"
     CDS             2670..3473
                     /locus_tag="OE968_003630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HCP7220859.1"
                     /translation="MNKKGFTLIELLVVISIIGILVIVAVPALFRNIEKSKAVTCLSN
                     RENIKTQIVIAMAEESSKGKNEVMKEVLENKDGKYFETEPKCKSGGIYSATFDDGYDG
                     ITGIESIAKVYVTCTKHPDGVEMARDIHQSMKDLIASFSQDPSIIPGASKGNDDFRKY
                     LLDNKYKNGWPTIPDEFKAKYGLSKDTLYIQPYAYSPTKSDATVVVFANNKTGGNWYT
                     SLVYDYDEGRWYKGKNGISVAGRSWDVDTDSVKSVKTEIHSKEGWGPLN"
     gene            3716..4357
                     /locus_tag="OE968_003631"
     CDS             3716..4357
                     /locus_tag="OE968_003631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase"
                     /protein_id="HCP7220860.1"
                     /translation="MNNNFQDNQTINLIQSRRSIRKFTTEQISDEQVNTLLHCAFAAP
                     SGCNKQPWHITVVQDQKLLKEISDDTLSRIHEVSNVEINKNFKLFYGAPTVLFISYDE
                     SSSWAPYDIGILTGNITTAAQALGLGSCIIGMVRGLFTPVEQGDIEGLVSVLDKEDVK
                     ESESIKMKFDTNKKYRELLDIPEGYSVPFGIAVGIPDGNLPNAREVVYKVSRV"
BASE COUNT         1895 a          449 c          918 g         1459 t
ORIGIN      
        1 aagtgaaaaa actagctttt catgaaataa tattttataa tttaagattg tctttttaat
       61 aaagattaac aaaaaaaata ctataattag tggtataata gttagagttg aagattttaa
      121 ataaaggtag gtgtaattaa gttggaaata tacttagaca atagcgcaac tacaaaacct
      181 tatcaagaag ttatagataa aatggtttat gcacttaata cggaatatgg aaatccttct
      241 tctgtccata gaaaaggtgt agaagttgaa aaagctataa aagaagtaag acaagatata
      301 gctaaatctc taggagcgaa agaaaaggag atttatttta catcaggtgg tacagagtgt
      361 aataatacta taataagagg tattactagt ttaaataaaa aaagaaaaaa tcacataata
      421 tctactaaca tagaacatcc ttctgtttta aatacattaa aagatttaga agaagatggt
      481 tttgaagtaa cttatttaga ggtcggaaaa gatgggaaaa taaatataga ggatttaaaa
      541 aatgcgataa agtcaactac atgcttagta agcatgatgc atgttaacaa tgaaatagga
      601 actatacagc caataggtga agttggaaag tatttgaagg gtttaaaaga aaaaatttat
      661 ttccatgttg atgctattca gtcatatgga aaaattaatt ttagactatc taaatacaat
      721 atagatttta tgagtgtaag tgcacataaa tttcatggtc caaagggaat tggatttatg
      781 tatataaaag aaaataatcg ccttaagcct atgttaacag gtggtggtca ggaaattgga
      841 attaggtcgg gaacagaaaa tgtacctgga atatatggtc ttggagaagc tgttagaata
      901 ctaaacaaag atttagatgt tgttatttcg aaagtaaata acttaaaaaa tatattaaaa
      961 aatgaaataa ttgataatat agaagatata aaaattaatt ctccagaaga tggagtatgt
     1021 catatattaa atgtatcatt tagagggaca aaaggagaag ttttacttca ttacttagag
     1081 caaaagggta tttatgtatc aactggctct gcatgttctt ctaaaaagaa aggtagttac
     1141 gtattaaatg ctataggtct tacaaatgaa gaaataaatg gaacaataag atttagttta
     1201 tctgatatga atacagaaga agaaatgtta gaagctgtga aagttttgaa agaatcaatt
     1261 tgtgacttaa ggtcaataat gaaaagaaaa taaagaatac tgtatagata gtgataataa
     1321 attagtttaa gaggtgaaat ggtgtataat atattaatag taaagtatgg agaaattgga
     1381 gtaaaaggaa agaatagata tatatttgag aataggctta taagaaacat aagaaatatg
     1441 ttaaaaccaa ttggaagatt taatgtatat aaagagtatg gaagaatata tgttgattta
     1501 gaagactatg attatgaaga agtaattgaa gaagttagaa aagtatttgg gatagtgggt
     1561 gtgtgccctg gagtaagagc taaaaaagat tatgatacat taaaagaaat agctttaaaa
     1621 atgttagaag aaaaaataga ggctggatat aaaactttta aggtagagtc aagaagagga
     1681 gataagtctt tcgggttgac ttctcaagaa atgagtatgg atataggtgg atacttatta
     1741 tcaaaggtag gagataggat taatgttgat gtaagaaatc cagaagttaa aataaagtgc
     1801 gaatacagag aatttcatac tatggtctat agtgatacta tacctggata tggtggattg
     1861 ccacttggaa cgaatggtag agctatgtct cttttatcag gaggtataga tagcccagta
     1921 gctacatgga tggttgcaaa aagaggtatg gaagtagagg cagttcactt tcatagttat
     1981 ccatttacaa gtgaaaggtc acaggaaaaa gttaaggatt tagctaaaat actggcaaaa
     2041 tactgtggta gagtaaggct tcataaagtt aatatcttag aaatacaaaa agcaattggc
     2101 gagaattgta atgaagaaga agctactatt ctttcaagaa gatttatgat gaggatagca
     2161 cagagacttt ctgaaaaaag acattgtgat gctttaatta caggtgaaag tattgggcag
     2221 gttgcatctc aaactataca aggacttact tgtactaatg ccgttgtaga cttaccagtg
     2281 tttagaccac ttatagcaat ggataaatca gatatagttg atatagccaa aaaaataggg
     2341 acttttgaaa catctatatt gcctgaagaa gattgttgta gtgtattttc tcctagaaag
     2401 cccgtcacta aacctagatt agagaaaata gaaaaatctg aaacagcact tgacattgaa
     2461 aaattagtac aggatgctat tgacaaaata gaggtagagg atattgagtt ttagcataca
     2521 agttatttaa ttactaaatt gaatattgag tatattagta gttctgtaag tatattagta
     2581 gttctgttga aaggatttat gtagacaatt tattaatatg tagtatttaa aaataagtac
     2641 tataatttta tttaatggga atgattatta tgaataaaaa gggttttaca ctaattgaat
     2701 tgttagtagt tatatctata ataggcattt tagttatagt agctgttcca gcattgttta
     2761 gaaatataga aaaaagtaaa gcagttacat gtctttctaa tagagaaaat ataaagactc
     2821 aaattgttat tgcaatggct gaggaatcaa gtaaaggcaa gaatgaagtc atgaaagagg
     2881 tattagaaaa caaagatggt aagtactttg aaacagaacc aaagtgtaag tcaggtggaa
     2941 tatattcagc aacgtttgat gatggttatg atggaataac tggaatagaa agcattgcaa
     3001 aagtgtatgt tacttgtaca aaacatccag atggtgttga aatggctagg gatatacatc
     3061 aaagtatgaa agatttgatt gcatcatttt cacaagaccc ttctataata ccaggagcct
     3121 caaagggtaa tgatgatttt agaaaatatt tattagacaa taaatataaa aatgggtggc
     3181 ctacaattcc agatgaattt aaggcaaaat atggattaag taaggataca ctatatatac
     3241 aaccatatgc atatagtcct actaaatctg atgctactgt agttgtattt gcaaataata
     3301 agactggggg taattggtat acttccctag tttacgatta tgatgaaggt agatggtata
     3361 aaggtaaaaa tggtatttct gttgcaggta ggtcatggga tgttgacaca gatagtgtta
     3421 agtctgtaaa aacagagatt cattctaaag agggatgggg tcctttaaat taatatatca
     3481 tgttttatta atctggtatt gattaaacta tagaaaagag cagtttctat agatgacgaa
     3541 taccagattt tcatttatat atataattga gatatattaa aagtgtttat atttttaagt
     3601 cttcacatac aagctaaaaa taattataat aatattgtaa agaaatttaa ttataagatt
     3661 aattttctga agatttagta tttgtactaa gaaatacata aaaaggggaa tagatatgaa
     3721 taataatttt caagacaacc aaacaataaa tttaatacaa agtcgtagaa gtatacgaaa
     3781 atttacgaca gaacaaatta gtgatgagca agtaaacaca ttattacact gtgcatttgc
     3841 agcaccttca ggatgtaata aacagccttg gcacataact gttgtgcaag accagaaact
     3901 tttaaaagag attagtgatg atactttatc taggattcat gaggtgagta atgttgagat
     3961 aaataaaaac tttaagttat tttatggtgc tccaaccgtt ttatttattt cttatgatga
     4021 aagtagttca tgggctccat atgatatagg aatacttaca gggaatataa caacagctgc
     4081 acaagcacta gggcttggaa gttgtataat aggaatggtt agaggtttat ttacacctgt
     4141 tgaacaaggg gatattgaag gtcttgtgag tgtattggat aaagaagatg taaaagaatc
     4201 agagtcaata aagatgaagt ttgatacaaa taaaaaatac agagaactac ttgatatacc
     4261 agaagggtat tctgtaccat ttggtattgc tgtaggtatt ccagatggaa atttaccaaa
     4321 tgctagagag gtagtttata aagtttccag agtttaggat aaagtattgc aagaaccaat
     4381 cagttacttg aagaattaaa ccagtaatat acaaataaat tgatggaaga ggaagctatt
     4441 taaaaagtag tttagatttt tcgttgtaaa ataattaaat aaagaataag gtgataagta
     4501 ttttatttat tatcttattc ttttttattt ttgttttgta gaatgataaa aataaggatt
     4561 aagtgtaata aaatagaaaa caagtatgtt aattttaagt atatgcttta aaatttatcc
     4621 aagttaaaaa tttaagatat cttttcagta taatggaaaa aatgtcaaaa tattgaaata
     4681 gggaaaaaat agtgatataa taagaaaaaa tagagaaaaa a
//
LOCUS       DAJMZY010000177         4662 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.182, whole genome shotgun sequence.
ACCESSION   DAJMZY010000177 DAJMZY010000000
VERSION     DAJMZY010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4662)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4662)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4662
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.182"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     repeat_region   143..1292
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=209..237
                     /rpt_unit_seq="atttacataccacatagttaatataaaac"
     gene            1939..3210
                     /locus_tag="OE968_003632"
     CDS             1939..3210
                     /locus_tag="OE968_003632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HCP7220861.1"
                     /translation="MLKVLKGNIIFTKTSETFTVFENSYIILEKGKVKGIFKEIPKEY
                     KNLKVVDYTDKLIIPGMNDLHAHASQFKNLGMAMDKELLPWLETYTFPEESNYKDIEY
                     ATKMYKKFVKELWKSGTTRIAVFATVHKEASMKLMDIFKEVGLGAYVGKVNMNMNCPD
                     TLLENTQDSITDTEEIINKYSDTDSIVKPIITPRFIPSCTSELLKGLGDLCLKYNIPI
                     QSHLSENYDEIEWVRSLEPESKFYGDAYNRYNLFGQTPTLMAHCVHCSQDEIDLMREN
                     NVMAVHCPASNFNVGSGAMPIRKLIDNNIRLALGSDISGGHTLSIFKAMVSAIQLSKL
                     YWVNSGKKYNFLSLSEAFYIATKSGGSFFGKVGSFEEGYDFDALIIDDSNLNHDNYSI
                     LERLERFIYVGDDRNIIHRYVCGKLIEEPNI"
     gene            complement(3850..4605)
                     /locus_tag="OE968_003633"
     CDS             complement(3850..4605)
                     /locus_tag="OE968_003633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1835 domain-containing protein"
                     /protein_id="HCP7220862.1"
                     /translation="MAHICFEDICYLLLKEAMKLKLIPHNKIVLFEDDLSIGNIFDVN
                     NYELRENIFKIRNVFENNPKLLFKPDLLEDRKLSKCRNIIIWCANNPKDLCGVYYVVS
                     KFQDKNIKIALVDEKKTEDALIRYSFTSEMSPEDFPFFLDKTLEIGFNEKLEFKNKWD
                     VLVKENSIFRALVGNEIKSVEETYFDKYILRNISDKWQPLIEVVANCMFEDEMRVKDW
                     FILWRLEKMASLKIVKIKGSKGDFYSDKEIRKV"
BASE COUNT         1788 a          643 c          513 g         1718 t
ORIGIN      
        1 attctacttt tatattttaa tcattaaaac taaagtcaat gttatctggt aattatttac
       61 tacaaatgct aaaaaataat tatattttaa aggataaaat gctgtataaa ttattggggt
      121 attttaccta tacttgttgc aaatttacat accacgtagt taatataaaa caagatgttt
      181 ttaaaaataa acttaatata gatattgaat ttacatacca catagttaat ataaaacttt
      241 aatcatatat cagataggtc acaacttaag agtgatttac ataccacata gttaatataa
      301 aacaacttct catattccag ataattgtta ttttacgaaa tttacatacc acatagttaa
      361 tataaaacct gtagatttgc ctgtttcgat attgctcatg tgtgaattta cataccacat
      421 agttaatata aaactctctt gtttcttctg ttaattttat tataccttca ttatttacat
      481 accacatagt taatataaaa cgcgttatat tgttgtataa aaccgattaa agttcaattt
      541 acataccaca tagttaatat aaaacttgca acatattgtt ttatcgttgc tgggtcttta
      601 aaaccattta cataccacat agttaatata aaactaagcg atattagaga gcgcaaggca
      661 tagcggagca aatttacata ccacatagtt aatataaaac tttaatttta accaccccct
      721 ttcactaata aaaaaagatt tacataccac atagttaata taaaacaaga cgctatacaa
      781 gaggtaattt gaaagcaatc taatttacat accacatagt taatataaaa cgttgcatat
      841 gtatgtctaa gagcatgaaa tttaatttta tttacatacc acatagttaa tataaaactt
      901 ctattaagtg taagcaaaac gcttggaata tgaaatttac ataccacata gttaatataa
      961 aacttataca caaatacaac ttgaagaagc gctaaagaga tttacatacc acatagttaa
     1021 tataaaacct aatgagtaca tagataaacg tacaggagag gttaatttac ataccacata
     1081 gttaatataa aacgttgata attttcgttt gtatactttt tataatttaa aatttacata
     1141 ccacatagtt aatataaaac ataaagattt agaaaaagaa aaagttaaaa ttttggaatt
     1201 tacataccac atagttaata taaaactttt cctgttaagt tgatgtttgc aactttaact
     1261 gctatttaca taccacatag ttaatataaa accccaaaat aaactaagta ttttcagtac
     1321 ttacacacat acaactctct caaatttgca gtgaaccatg agtagtgcaa ttgataacat
     1381 ttatcacaca ccctcaatcc cttacattgc aactgttaaa ccctacttta tcaaaaatat
     1441 cgctcactgc aaaatttata tatttttatt atatcataaa attcaaacta taaaattaaa
     1501 atggaataat ttatcaattt aagaacacct acatatttgt aaatacttac tatattatct
     1561 attctaataa ttcttcttct agctggaact aatataaaaa tcatctctga aagattagga
     1621 catactaata taaaaataac tatgaataga tattttcttg ttttaaacga tatggataaa
     1681 aaagcttctg aaaatataat caaagttctc tttaaataac attccatttt atgtaagtag
     1741 gcattatatt tttcttaaat gtcacttaaa tgtcagttat atataataat agtaaacaac
     1801 tgtatttcac taatatttgc tattatctaa tagtatttat agtttagatt tgatataata
     1861 catgtggtaa aattttgatt tgtaaaacaa aattttacct acatatatta aaacaaattt
     1921 aaaactaagg agacctatat gttaaaagta ttaaaaggaa atataatttt tacaaaaact
     1981 tcagaaactt tcacagtatt tgaaaatagt tatattatac tggaaaaagg taaagtaaag
     2041 ggaatattta aagagatacc taaggaatac aaaaacctaa aagtagtaga ttacactgat
     2101 aagcttataa tacctggtat gaatgacctc catgcccatg cctctcaatt taaaaatctt
     2161 ggaatggcta tggataaaga gcttttgcca tggcttgaaa cttatacatt tccagaagaa
     2221 tcaaattata aagatataga atatgcaaca aaaatgtata aaaaatttgt aaaagaactt
     2281 tggaaatctg gaactacaag aatagcagtg tttgcaacag tacataaaga agcctctatg
     2341 aaacttatgg atatattcaa agaagttggt cttggagcat acgttggtaa agtaaatatg
     2401 aatatgaatt gccctgatac tttattagaa aacactcagg attctattac tgatacagaa
     2461 gaaattataa ataagtatag tgatacagat tctattgtaa aaccaataat aacacctaga
     2521 tttataccaa gctgtacaag tgaactttta aaaggtttag gagatttatg tttaaaatat
     2581 aatattccta ttcaatcaca cttatctgaa aattatgatg agattgaatg ggttagaagt
     2641 ctagaacctg aatctaaatt ctatggagat gcatataata gatataattt atttggtcaa
     2701 actcctactt taatggctca ttgtgttcat tgttctcagg atgaaataga tttaatgaga
     2761 gaaaataatg ttatggcagt tcactgtcca gcttctaact ttaatgttgg tagtggtgct
     2821 atgcctatca gaaaattaat cgataataat attagattag cacttggatc agatataagc
     2881 ggtggacata cattgtcaat atttaaagca atggtatctg caatacaatt atctaaatta
     2941 tattgggtta attctggtaa gaagtataat ttcttatctt tatctgaggc tttttatatt
     3001 gcaaccaaaa gtggtggaag tttctttgga aaagttggta gctttgaaga aggttatgat
     3061 tttgatgcat tgattattga tgattcaaat ttaaatcatg acaattattc tatacttgaa
     3121 agacttgaaa gatttatcta tgttggtgat gatagaaata tcattcatag atatgtatgt
     3181 ggaaaactaa ttgaagaacc taatatataa ttataataaa aattttaatt atatattatg
     3241 gttaatttat acaactataa ttaataaaag agtatatttt aaatctaaaa gctataggtt
     3301 gaaacatact ctttttattt tgtttattta tagctttagt tattaatcat atataaatct
     3361 acaaaacgta ttcctagtaa cttatatttt ttgatatcta caatcataag actatattat
     3421 tggattcata cctcaaaaat attgccttct gaacattatt atattcaaag ctatgttaat
     3481 ttacaatgat atatcctaac atgtattgat taaaaaaaat taaaacttgc ttttcatctc
     3541 ctatatctaa agaagtggta tttagaataa actattgtaa tattaaagtt gaaattttct
     3601 agtttattta ctctatagca ccatatttta atactattaa gtaaaaatgt agttaaaata
     3661 tatactaata tccctgaaat aagtatttct tttttattta gcacacttat tcgtaaggta
     3721 ttagttatta tatttccaaa ttatagaata aatattatac ttattgctaa ttataatatt
     3781 aatactgtta agatattttt cttcatagtt atacccatta tttaatacaa tttattataa
     3841 attcaatttt taaacttttc ttatctcctt atcagaataa aaatcccctt tacttccttt
     3901 tatttttact atttttaaac ttgccatctt ctctaatctc caaagtataa accaatcttt
     3961 tacacgcatt tcatcttcaa acatacagtt tgcaaccact tcaattaaag gttgccattt
     4021 gtcactgata tttcttaata tatatttatc aaaataagtt tcttcaacac ttttaatttc
     4081 gttacctact aatgctctaa aaatagaatt ttctttaact aacacatccc atttattttt
     4141 aaattctagt ttttcattaa agccaatttc tagtgtctta tctaaaaaga atggaaaatc
     4201 ttctggagac atttcactgg taaatgaata tctaattaga gcatcttctg tctttttttc
     4261 atctactaat gcaatcttta tatttttatc ttgaaactta ctcactacat aatatactcc
     4321 acacaaatct tttgggttat ttgcacacca tattattata tttctacatt ttgataattt
     4381 cctatcttct aacaaatctg gcttgaataa tagtttcgga ttattttcaa aaacatttct
     4441 aatcttaaaa atattttctc ttaattcgta gttatttaca tcaaaaatat tacctattga
     4501 taaatcatct tcaaataata caattttatt atgtggtatt aactttaact tcattgcttc
     4561 ttttaataac aaataacaaa tatcctcaaa gcatatatgt gccataaaat tcacctcttt
     4621 taaaattaac aatttatttt attataatat ataaactgta at
//
LOCUS       DAJMZY010000178         4594 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.183, whole genome shotgun sequence.
ACCESSION   DAJMZY010000178 DAJMZY010000000
VERSION     DAJMZY010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4594)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4594)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4594
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.183"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            complement(441..2828)
                     /gene="cadA"
                     /locus_tag="OE968_003634"
     CDS             complement(441..2828)
                     /gene="cadA"
                     /locus_tag="OE968_003634"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HCP7220863.1"
                     /translation="MEANNSIKKEFILGGLNCAHCAEEINNKVSKLQEVKSSNLNFIN
                     KKLTVNIKESFNEDTTIEKIIDIIDSTDPGLDIQISSKENAASKTSIKKELILGGLNC
                     AHCAEEINNKVSKLKEVESSNLNFVNKKLTVNISNNFEEDDVINKIKEIINSTEPGLD
                     IQVGSTDKVKGRTTEKSGAVNDTNKKELIPLIIGALVYIFGIYQTATGYESQFSNIVF
                     IVAYVIVGGDVLLRAIRNISKGRVFDENFLMALATVGALTIGELSEAVGVMLFYKVGE
                     YLQGVAVGKSRKSITSLMQIRPDYANLKVNSEVKVVSPEEVNVGDIIVVKPGEKVPLD
                     GVVVDGVSMLDTSALTGESVLREVEKGDEILSGVINKNALLSIEVTKSFGESTVSKIL
                     DLVENSSIKKSKTENFISKFSRYYTPIVVIAALLIAFVPPLVISGEVFSDWLYRGLIF
                     LVVSCPCALVLSIPLSFFSGIGFASKNGILIKGSNYLEALRSVDTVVFDKTGTLTKGV
                     FNVTKLNPEGISEEELLEYAAIAEVNSNHPIAKSILSYYNKKIDLDTIDSYEEIAAYG
                     IRVKHNGNFILAGNEKLMKKENISYSSAKEVGTVVYIAVDKVYRGYIVISDEVKEDSK
                     NAIRSLKEIGVKEVVMLTGDNEKVAKNIAQELELDTVYSNLLPNEKVDRLEDLYEGRT
                     EKEKIAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVLMTDEPSKISKAIEIA
                     NKTNKIVWQNIIFALGVKIIVMILGAGGVATMWEAIFADVGVALIAVVNAMRAMR"
     gene            complement(2851..3216)
                     /locus_tag="OE968_003635"
     CDS             complement(2851..3216)
                     /locus_tag="OE968_003635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCP7220864.1"
                     /translation="MREEINDCNCNIVHEEIVTEAKSTMPDEEMLYDLAELFKVFGDT
                     TRVKILYALFANEMCVCDIASLLNMTHSAISHQLRVLKQARLVKFRREGKTVYYSLDD
                     SHISQIFDCGLNHIRETYK"
     gene            3415..4263
                     /locus_tag="OE968_003636"
     CDS             3415..4263
                     /locus_tag="OE968_003636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220865.1"
                     /translation="MSNKKKKDLDTSYMPYLDPANYADYITNEEIPQDELRNDPQISN
                     GYTKIPNNQNINNLYPNNVNHYPKSSNSPNNLPNTNNTSGNMNYNTSATNNMPNNMNN
                     NTGMPNNMSNNMNSNMGMPNNMPNNMNSNMGMPNNMPNNMNSNMGMPNNVPNNMNSNM
                     GMPNNMSNNMNSNMGMPNNMSGNMNNNMYGNTGMPNNMNSNMGYNMNNTMGIPNFSCN
                     QNMPPNVLMMIPGVICHNTMQGMPVVMPSTMPPNIYPTPYGSSNMSVQGIPQATNIEE
                     FDEEEM"
BASE COUNT         1567 a          797 c          498 g         1732 t
ORIGIN      
        1 cttaaaaata attcgtcaat actttttaaa attatttttt aaaaatattt actttcttat
       61 attacataat ttattgaatg gcagtcatac tgttggttta gagtatttta acacacacat
      121 tttgttgtaa aaattacaac tattaatata atatatatac aatcataagt attataattt
      181 ttatgaatct aatttaaact taatataaac ttattaataa accttctatg tctaaatttt
      241 aaaattacaa tataaaagct ctacactaaa taaatacatt aaataaacat aatggataat
      301 gaatataaat ttatatatgc aaagcgctcc aataaaaagg taccaataaa gttaaaagaa
      361 acttattgat acctttcatt attacatact tcaatatata attataagtt ttttaaatag
      421 tatggattta catttatccc ttatctcata gctctcatag catttactac tgctataagt
      481 gccacaccta catcagcaaa tatagcttcc cacatagtag ctactcctcc agcacctagt
      541 atcataacta taatttttac tcctagagca aatattatgt tttgccacac tatcttatta
      601 gtcttgtttg ctatttcaat tgctttagat atcttgctag gctcatctgt cataagcact
      661 acatctgcag cttcaatagc agcatctgaa cctaagcctc ccatagctat accaacatca
      721 gcacgagcta atactggagc atcatttatt ccatcaccta caaacgctat tttctctttt
      781 tcagttcttc cttcatataa atcttctaat ctatctacct tttcattagg aagtaaattt
      841 gagtaaactg tatccaattc taattcttga gcaatatttt ttgctacttt ctcattatct
      901 ccagttaaca ttacaacttc ttttacccct atttctttta agcttcttat ggcattttta
      961 ctatcttctt ttacttcatc agagataact atataacctc tatatacttt atcaacagca
     1021 atatagacta ctgtgcctac ttctttagct gatgaataag atatattttc ttttttcata
     1081 agtttctcat tacctgctaa tataaaattg ccattatgct ttactctaat tccataagct
     1141 gctatttcct cataactgtc tattgtatct aaatcaattt ttttattata gtaacttaat
     1201 atggactttg ctattggatg atttgaattt acctccgcaa tagctgcata ttctaataat
     1261 tcttcttctg atataccttc aggatttaac ttagttacat tgaacacacc tttagtaagt
     1321 gttcctgttt tatcaaatac tactgtatct acacttctta aagcttctaa atagttactt
     1381 cctttaataa ggataccatt tttagatgca aacccaattc cactaaaaaa actaagtggt
     1441 attgataaaa ctaatgcaca agggcaagaa acgactaaga atatcaatcc tctatataac
     1501 caatcactaa atacctcacc tgagattaca agtggtggca caaatgctat taataaagca
     1561 gctattacta ctattggagt atagtatctt gaaaacttag atataaagtt ttctgtcttt
     1621 gattttttaa tgctagaatt ttcaacaagg tcaagaatct tagaaactgt tgattctcca
     1681 aaactctttg taacttcaat actcaataaa gcatttttat ttataacacc tgataagatt
     1741 tcatctcctt tttcaacttc tctcagcact gactctcctg tgagtgcaga agtatctaac
     1801 atagaaactc catctactac tacaccatct aatggtactt tttcaccagg ttttactact
     1861 attatatcac ctacatttac ctcttctggt gacaccacct taacttcaga attaactttt
     1921 agatttgcat agtctggtct tatttgcata agtgaagtta tagactttct ggatttacca
     1981 actgcaacac cttgtaaata ctctcctact ttatagaaaa gcataacccc tactgcttct
     2041 gataactccc ctattgttaa tgctcctact gttgctagag ccatcaaaaa gttctcatca
     2101 aatactcttc cttttgatat atttcttatt gctcttaaaa gcacatcacc acctactatt
     2161 acataggcaa ctataaatac tatattgcta aactgacttt cataacctgt agctgtttga
     2221 tatataccaa atatatatac aagtgctcca attataagtg gaattaattc tttcttattt
     2281 gtatcattta cagctcctga tttttcagta gttctccctt ttactttgtc agtagaccct
     2341 acttgtatat caagccctgg ctctgttgaa tttattattt cttttatttt atttataaca
     2401 tcatcctctt caaagttatt acttatattt actgtaagtt ttttatttac aaagtttaaa
     2461 ttagaagatt caacttcttt taatttagaa actttgttat taatctcttc tgcacaatga
     2521 gcacagttta atcctcctaa tataagctct tttttaattg atgttttact agctgcattt
     2581 tctttagaac ttatttgtat atcaagacct ggatctgttg aatctattat atctattatc
     2641 ttttctatag tagtatcctc attaaaactt tcctttatat ttactgtaag ttttttattt
     2701 ataaaattta aattggaaga tttaacttct tgtagtttag aaactttatt attaatctcc
     2761 tctgcacagt gagcacaatt taatcctcct agtataaatt cttttttaat tgaattattt
     2821 gcttccatat atattcactc ctctcattta tcatttataa gtctctctaa tatgatttaa
     2881 tccacaatca aatatctgac ttatatgact atcatctaat gagtaataca ctgtttttcc
     2941 ttctcttcta aactttacta atctagcctg ctttaatact ctaagttgat gagatattgc
     3001 agaatgagtc atatttaata aactcgctat atcacataca cacatttcat ttgcaaataa
     3061 tgcatataat atctttactc tagtagtatc cccaaatact ttaaataatt ctgctaaatc
     3121 atataacatt tcttcatctg gcatagttga tttagcctct gttactattt cttcatgtac
     3181 tatattacaa ttacaatcat ttatctcttc tctcattttt aatcctccat tattttaata
     3241 tatgaataac tgttcatatg ttcattatat gttatcattt ctaaatttgc aacaataatt
     3301 tttattaatt taatataaat agaatgcaca tattataaac ttttttaata tatatattat
     3361 tagaataagt ttttgtaaac ttttttatag ttttctagga ggtgcaagtt taatatgagt
     3421 aacaagaaaa aaaaggattt agatactagt tacatgcctt acttagaccc agcgaactat
     3481 gcagattata ttactaatga agaaattccc caagatgaat tgagaaatga ccctcaaatt
     3541 tctaatggtt atacaaaaat acctaataac cagaacataa ataacctata tcctaataat
     3601 gtaaatcatt atcctaaaag tagtaattct ccaaacaact tgcctaacac aaataataca
     3661 tccggaaata tgaattacaa tacatctgct acaaataata tgcctaataa catgaataat
     3721 aatacgggta tgcctaataa tatgtctaac aatatgaata gtaatatggg tatgcctaac
     3781 aatatgccta ataacatgaa tagtaatatg ggtatgccta acaatatgcc taataatatg
     3841 aatagtaaca tgggcatgcc taacaatgtg cctaataaca tgaatagtaa tatgggtatg
     3901 cctaacaata tgtctaataa tatgaatagt aatatgggca tgcctaacaa tatgtctggc
     3961 aatatgaata acaatatgta tggtaataca ggtatgccta ataacatgaa cagtaatatg
     4021 gggtataata tgaacaatac tatgggtatt cctaacttct catgtaatca aaatatgcct
     4081 cctaatgtac ttatgatgat accaggagtt atatgtcata atacaatgca aggtatgcct
     4141 gtagttatgc ctagtactat gcctcctaat atatatccta ctccttatgg ttctagtaat
     4201 atgtctgtac aaggtatacc acaagctact aatattgagg aatttgatga ggaagaaatg
     4261 taatatatat ttttttaagt aagttgtata aaacattaat aattgaccat aataataaat
     4321 gtattcctca taatattccc ccaatattat tataggtata gaaagttgac tgaatatgcg
     4381 cttattcggt caacagatat taacataatc taataagata aacatagaaa aagtcagata
     4441 aaatttaatt ttatctgact ttttcattta aaaatgctct cttgtgttgg tgattcagaa
     4501 tagtatggta ctcgtatttg agactaatat tggcaaacaa cataaagaaa aatataaatt
     4561 ttttataata aactgtataa aattttaata attg
//
LOCUS       DAJMZY010000179         4480 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.184, whole genome shotgun sequence.
ACCESSION   DAJMZY010000179 DAJMZY010000000
VERSION     DAJMZY010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4480)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4480)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4480
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.184"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            <1..1861
                     /locus_tag="OE968_003637"
     CDS             <1..1861
                     /locus_tag="OE968_003637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HCP7220866.1"
                     /translation="STKDTEVKAKYTEIKILGTGDLHSILTDSMVSYVNEEREKNKNL
                     LMVDAGDFYGTQSREMWEWSSGKKLINIKRNGRAEYDDIIKSSKDEVPIVKDMAKLKY
                     DAVVLGDNEFVSNDKQSLDKLVSDFKNNNMPLVSANIYEQSGENYVQPYVMKNIKTDE
                     GNVKVGILGLTIKEVGETLGLEDFEKDKKARELGEQADYKGKLYANDLVEDAKKWIKV
                     MEKESPDIIVAVVHSGEEPKTDRNPGNRIKELATTVDGIDAIVAGHTHEKIDEHKYKN
                     KSGDEVIVTQPGWHGDRVSEINFKLNKENGKWDIKEKSSKLKIIDKEVSIVATADLHS
                     HFSDKLTVDLVNERSNPIEPVVVDAGDFLDPQTDEMTQWYKEWKSIRDNNSDKTISRC
                     PMVMDMNQGMYDAVVLGNHEFVSEKDEFWSDERLLDAVIEDFEQVAISVLSANIYRQS
                     GKNYVKPYIIKDVETSEGNVKVGILGLTIKEVGKGLKNVNLQEQFQYKDKLYANDLVE
                     DAKKWVKVMKKKKPDIIVAVVHSGEEPKNPKHPGNRIKELATTVDGIDAIVASHTHEK
                     IDEHEYKNKSGEKVIVTQPGEHGKYYSKITFKVNKEKGSWIINDKFSKTIEVE"
     gene            2262..4166
                     /locus_tag="OE968_003638"
     CDS             2262..4166
                     /locus_tag="OE968_003638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HCP7220867.1"
                     /translation="MKIKFIIVASIIFLIVLLVGCQSTKDTEINVLATSDLHSIIPDN
                     LISYVEEERKYDENLLMVDAGDFFDMQSGEMNKWFTGQKLVRFKDGIPEYKKIAEPRE
                     GEVPLAKKMAKLKYDAVTFGNHEFVSNDKQSLDKLVSDFKNNNIPLVSANVYEQSGEN
                     YVKPYVMKNINTDKGTVKVGILGLTIKEVGERSRFKSFEQDKKARELGEQPQYKGKLY
                     ANDLVEDANKWVKVMEKKEKPDIIVAIVHSGEEPKNPKNPGNRIKELATTVEGIDAIV
                     AGHTHEKIEQHTYKNNSGEEVIVTQPGAHGNSISKINFKLDKKNDKWFIKDKYSELKI
                     FGKEVNIITTSSLNPKFSDEMAVNLFNERDRDVQPIFIDTGDFLNTNTKEMTKWAKEW
                     QYNENKGIYKKINEWPIVYLGYDAVVLGSHEFTEDKETFEEKKSTLDYIIENFEEMKI
                     PVLSANIYDESGENYVKPYIIHNVETREGNIKVGVLGLTTTDKDEEDLSSSSLSKDSK
                     TSKIPEETGKLYTNNLVKDASEWVKVMQKESPDVIVAVVHSDNNSTLKNPSSEVKKLA
                     MSVDGIDAIVVGHTKNKVEEHIYKNKSGDEVIVTQSGEDCYSKISLELRKENGKWNII
                     NKYSKAIKMK"
BASE COUNT         1897 a          457 c          833 g         1293 t
ORIGIN      
        1 aagtacaaaa gatacagaag ttaaagcaaa atatacagaa attaaaatat taggtacagg
       61 tgatttgcat tcaattttga cagactctat ggtttcatat gtaaatgagg aaagggaaaa
      121 gaataaaaat ctgcttatgg tagatgcggg agatttctat ggtacacaaa gtagagaaat
      181 gtgggaatgg tcttctggaa aaaagttaat taatattaaa agaaatggta gagcagagta
      241 tgatgacata attaagagta gtaaagatga agtacctata gttaaagata tggcaaagtt
      301 gaaatatgat gctgtagttt tgggagataa tgaatttgtt tcaaatgata agcaaagtct
      361 tgataaacta gtttctgatt ttaaaaataa taatatgcca ttggtatcag caaatatata
      421 tgaacaatct ggagaaaatt atgtacaacc atatgtaatg aaaaatatta agacagatga
      481 gggcaatgta aaagttggaa tactaggtct tactataaaa gaagtagggg aaacccttgg
      541 tcttgaggat tttgaaaagg ataaaaaagc tagagagctt ggagaacaag ctgattacaa
      601 aggaaaatta tatgcaaatg atttagtaga agatgcaaag aaatggataa aagttatgga
      661 aaaagaaagt ccagacataa tagttgcagt tgtacactca ggggaagaac ctaaaacaga
      721 tagaaatcca ggaaatagaa taaaagagtt agcaactaca gtggatggaa tagatgcaat
      781 tgtagctggt catactcatg aaaaaataga tgaacacaaa tataaaaata aatctggaga
      841 tgaagtaatt gttacacaac caggttggca tggagataga gtatcagaga ttaatttcaa
      901 attaaataaa gagaatggaa agtgggacat aaaggaaaag tctagtaaat taaaaataat
      961 tgataaagaa gtaagtatag ttgctactgc agatttacat tcacatttct ctgataaatt
     1021 aacagttgac cttgttaatg aacgtagtaa cccaattgaa cctgttgtag tagatgcagg
     1081 cgacttctta gaccctcaaa cagatgaaat gactcaatgg tataaagagt ggaaaagtat
     1141 aagagataat aatagtgata aaacgattag tagatgccca atggtcatgg atatgaatca
     1201 gggaatgtat gatgcagtag tacttggaaa tcatgaattt gtatccgaaa aagatgaatt
     1261 ttggtcagat gaacgccttt tagatgctgt tatagaggat tttgaacagg tggcaatttc
     1321 tgtgttatcg gcaaatatat ataggcaatc tggtaaaaat tatgttaaac catatattat
     1381 aaaagatgtg gagacgagtg aaggtaatgt aaaagtagga atattgggac ttactataaa
     1441 agaagtaggt aaaggtctta aaaatgtaaa cttacaagag caatttcaat ataaggataa
     1501 attgtatgca aatgatttag tggaagatgc aaagaaatgg gtaaaagtta tgaaaaagaa
     1561 aaaaccagat ataatagttg cagttgtaca ttcaggagaa gaaccaaaaa atccaaaaca
     1621 tccaggaaat agaataaaag aactagcaac tacagtagat ggaatagatg caattgttgc
     1681 tagtcatact catgaaaaaa tagatgagca tgaatataaa aataagtctg gagaaaaagt
     1741 tatagtgaca caaccaggtg agcatggtaa atattattct aaaattacct ttaaagtaaa
     1801 taaagaaaag ggttcgtgga ttattaatga taaattcagt aaaacaattg aggttgaata
     1861 actttataaa atttatagat aaagtaaatt atctgatatt gacatgatat ataagataaa
     1921 gtttctaata ttagtataat gcataatgtg aaatatttta ataataagag aataaacaag
     1981 acaaataaaa atattttaac atgtaagata tagtatgaac tattatacta atgcttactt
     2041 tataatttga acatgttaga ataagtctta tttgaaaatt ttagtgtatt agagtaagta
     2101 ttattttacc agtaaaaaat attgagaact atatgtagat ttgcttaaaa aggaatttac
     2161 atatagttct tttcgtataa taaatagtac aatcttatat ggtaaagata aagtgtgata
     2221 ttaaatttta ttatcatcca aaatctaagg aggagtctct tatgaaaata aaatttatta
     2281 tagtagcatc aataatattt ttaatagtat tacttgtggg gtgtcaaagt actaaagaca
     2341 cagaaatcaa tgtactcgcc acaagtgatt tacattcaat tattccagat aatttaattt
     2401 cctatgtaga agaggagaga aaatatgatg agaatctact tatggtagat gcaggagatt
     2461 tttttgacat gcaaagtggt gagatgaata agtggtttac tggtcaaaaa ttagtaagat
     2521 ttaaagatgg gataccagag tacaaaaaaa tagctgaacc acgtgaagga gaagttccat
     2581 tggctaaaaa aatggcaaag ctgaagtatg atgcagttac atttgggaat catgaatttg
     2641 tatctaatga caagcagagc cttgataaat tggtttctga ttttaaaaat aacaatatac
     2701 cattagtatc agcaaacgta tatgaacaat ctggagaaaa ctacgtaaag ccatatgtaa
     2761 tgaaaaatat aaatactgac aagggaactg taaaggttgg tatacttggt ctgactataa
     2821 aagaagtagg ggaacgttca aggtttaaaa gttttgaaca agataaaaag gctagagaac
     2881 ttggggaaca acctcaatac aaagggaaat tatatgcaaa tgatttagta gaagatgcaa
     2941 ataagtgggt aaaggttatg gaaaaaaaag aaaagccaga tataatagtt gccattgtac
     3001 actcaggtga agagccaaaa aatcctaaaa atccaggaaa tagaataaaa gaactagcaa
     3061 caactgtaga gggaatagat gctattgtag caggtcatac acatgaaaaa atagaacagc
     3121 atacatataa aaataattct ggtgaagaag taatagtaac acagcctgga gctcatggta
     3181 atagtatatc aaagattaat tttaagttgg ataagaagaa tgataagtgg tttataaaag
     3241 acaaatatag tgaattaaag atttttggaa aggaagtaaa tataattaca acttctagtc
     3301 tgaatccaaa attttcagat gaaatggcag ttaatttgtt taatgaaaga gatagagatg
     3361 ttcaacctat atttatagat actggagatt ttttaaatac taatacaaaa gaaatgacta
     3421 agtgggctaa agagtggcaa tacaatgaaa ataaaggcat ctataaaaaa ataaatgaat
     3481 ggccaattgt atatcttggt tatgatgctg tagtacttgg tagccatgaa tttacagagg
     3541 ataaagagac ttttgaggaa aaaaaatcta cattggatta tattatagaa aactttgaag
     3601 aaatgaagat accagtatta tcagctaata tatatgatga atctggagaa aattatgtaa
     3661 aaccttatat aattcataat gtagaaacta gggaaggaaa tataaaggtt ggagtattag
     3721 gtcttactac tactgataag gatgaagaag acttaagtag ctcaagctta agcaaagact
     3781 caaagacttc gaaaattcct gaagaaacag gaaagttata tactaataat ctagtaaaag
     3841 atgcaagcga atgggtaaaa gttatgcaaa aggaaagtcc tgatgtgatt gttgcagttg
     3901 tacattcaga taataatagt actctaaaaa atccaagtag tgaagtcaaa aaacttgcaa
     3961 tgtcagtaga tggaatagat gctattgttg taggtcatac gaaaaataag gtagaagaac
     4021 atatttacaa aaataagtct ggggatgagg ttatagtaac acaatctgga gaagattgtt
     4081 attcaaaaat aagtcttgaa ctaagaaaag aaaatggcaa gtggaatatc ataaacaaat
     4141 atagtaaagc aataaaaatg aagtgaattt attgatatat aaaccattat taacactgat
     4201 ttttataata taataaatac tgattctata atataattaa cactactttt tataatgtca
     4261 tcaacactga ttctataata taattaatac tactttttta aatataatca atactgattc
     4321 cataatataa ttaacactac ttttttaaat ataatcaata ctgattctac aatattatta
     4381 atactacttt ttataatata atcaacacta ctttttacaa tataatcaat actgattcta
     4441 taatataatt aacactactt tttaaatata atcaatatcg
//
LOCUS       DAJMZY010000180         4404 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.185, whole genome shotgun sequence.
ACCESSION   DAJMZY010000180 DAJMZY010000000
VERSION     DAJMZY010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4404)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4404)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4404
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.185"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            156..4289
                     /locus_tag="OE968_003639"
     CDS             156..4289
                     /locus_tag="OE968_003639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014466370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF11 domain-containing protein"
                     /protein_id="HCP7220868.1"
                     /translation="MATVSGQIVFDRNRSATIDSGDSGIANIPVVLQDIATGVRLVVL
                     TDASGNYVFTNVPNGNYRIVEAFGTTGGVPTPGNFATAIVGPVPIAEMPPISPPIGST
                     NLDGTTPNTLLITVAGSDITNQNILNGPVIYTPIENILDSCVSVSNINLITDADNGTF
                     GFFPPGTPSNTGPEIEPYPNVTPDFTYVVPDPTKFTPLDGEYTVQNIMTNAMSNVIGA
                     WWRIADHTTGNETGRMMVVNGFNPGAVFFKSTVQVTPNTNYLFSTWILNLFKVTGYPP
                     PQLGVRIFDQNNNILYQATLGAQIPVNTNAPEWKEVGTVINSQNNNQLTVEFFSEGES
                     AIGNDYAIDDVSLREIAVPTFTPIKTSNTETANVGDIITYTVTLDNTCDSPLTNVFFR
                     DLIPNGLEFIPGTVTVDGVSVPGVDPNTGFSLPDIGGGTGVEVTFDVVVESIPNPNPT
                     NNIANIDYSYTPVEGGIPNDFSVDSNPVPVEVISADIEVTKLSEPTIVNPGEELIYTI
                     KVVNNGPFPSENVVLTDDVPASIINPEYSLDGGVTFQPWTGSLNIGTLEVGETRVIII
                     RGIVNPSTVGIITNTAVVSSTTADPNLNNNTSTIETEVNLLADILVMKTAEPNSAVPG
                     TLLRYTIQVENLGPANAENVILNDDIPASIINPEYSLDGGASFQPWNGSLNIGTLNSG
                     ISLTVLIQGTVSLNSSEYIVNTATVSSTTPDPDLSNNISTIITPVNPQAGISIIKVAD
                     EDVAVPGEEFVYTIEIFNEGPSNATNVVLTDDIPDVILNPEYSLDGGATFQPWNGSLN
                     IGTVAPGQLIRIIIKGLVSSTATGDITNTAEVSADVPEPVTDSSTVTTPIVPSADIEV
                     IKTSNMDTAVPEETFSYTITVTNLGPSAAQSIVLTDDIPDVILNPEYSLDGGVTFQPW
                     NGNLSIGTLDAGEIRSIIIRGTVSQTAVGTIINTATISSPTPDPNPDNNTSTDETDIS
                     PLADISVIKGNEPVAIPGGRFIYGIEIANAGPSFAENVTLTDNIPASILNPEYSIDNG
                     VTFQPWNGSLNIGTLDAGEIRNIIIRGTVSQTAIGTIINTATVSSTTPDPNLNNNTST
                     SEAEVSSSADISVVKRSNQTVVVPGDVLDYTIEVRNAGPSTAQNVTLTDNIPASILSP
                     EYSIDNGVTFQPWNGSLSIGTLDAGEIRNIIIRGIVSQTAIGTIINTATVSSTTPDPN
                     PDNNTSTSEIDISSSADISVIKLANKTEACVGEQIDFVIVVSNAGPENAQNVTLIDNV
                     SDKLKKAVFSLDRGVSFQPWTGSLNIGTLPAGTLRVIILRGIIKSTCLDRLTNIAEVT
                     STTPDSNLNNNISRVQVEIKQFCCNDCGCKDCCCNCCCNDCGCKNCCCNCCKNDFWC"
BASE COUNT         1678 a          663 c          778 g         1285 t
ORIGIN      
        1 ataaaatata aaaaaattga tattgcaaat aaaaaaaata catattagat gttatagaaa
       61 aaaagcgcac ttataggctt aaaatgtcac ataaaagagt tttaaagaat aatatattat
      121 gaacacaaat tttgtaatca caaaggagtg ataatatggc aacagtatca ggacaaatag
      181 tttttgatag aaatagaagt gctaccattg attctggaga ctcaggaata gccaatatac
      241 cagttgtatt acaagatata gcaactggag ttagacttgt ggttctcaca gatgcatcag
      301 gaaattatgt ttttactaat gttccaaatg gtaactatag aattgtagaa gcttttggaa
      361 ctacaggagg agtaccaaca ccagggaatt ttgcaacagc gatagtaggt ccagttccaa
      421 ttgcagaaat gccacctatt agtcctccta ttggttcaac aaacttagat ggtacaacac
      481 ctaacacact attaataaca gtagcaggtt cagatataac aaatcaaaat atattaaatg
      541 ggcctgtgat ttatacacct atagagaata tattggattc ttgcgtatct gtatctaata
      601 taaaccttat tacagatgca gataacggaa cattcggttt ttttccacca ggtacaccaa
      661 gtaatacagg acctgaaata gaaccttacc caaatgtgac gccagatttt acgtatgttg
      721 taccagaccc aactaagttt acacctttag atggagaata tacagtacaa aatattatga
      781 caaatgcaat gagtaatgtt ataggagctt ggtggcgtat tgctgaccat actacaggaa
      841 atgaaacagg aagaatgatg gtggtaaatg gttttaatcc tggagctgta ttttttaaat
      901 caacagtaca agttacacct aacactaatt atttatttag cacttggatt ttaaaccttt
      961 ttaaggtaac aggatatcca ccaccacagc taggtgtaag aatatttgac caaaataata
     1021 atatactata tcaagcaaca ttaggagctc aaattccagt taatacaaac gcaccagaat
     1081 ggaaagaagt aggtactgtg attaattctc aaaataataa tcaacttaca gtagaatttt
     1141 ttagtgaagg agaaagcgcc attggaaatg attatgctat agatgatgtt tctttaagag
     1201 aaatagctgt tccaactttt actccaataa aaacaagtaa cacagaaact gctaatgtag
     1261 gtgatataat cacatataca gttacattag ataatacttg tgatagccct ttaactaatg
     1321 tattttttag ggatttaatt ccaaatggtt tagagtttat acctggaact gtaacggttg
     1381 atggagtatc tgtaccagga gtagacccta atacaggttt ctcacttcca gatattggag
     1441 gaggaacagg ggttgaagta acttttgatg ttgtggttga aagtattcct aacccaaatc
     1501 ctactaataa tatagctaat atagattact cctatacacc tgtagaaggc ggtataccaa
     1561 atgatttttc agtagattct aatccagttc ctgttgaagt aatatcagca gatattgaag
     1621 ttacaaaatt atctgaacct actatagtga atccaggaga ggaattaata tacactataa
     1681 aagtagtaaa taatggacca ttcccatctg aaaatgtggt tttaacagat gatgtaccag
     1741 cttctattat aaatccagag tattcattag atggaggagt aacttttcaa ccatggactg
     1801 gaagtttaaa tatagggaca ttagaagtag gagagacaag agttattata attaggggta
     1861 ttgtaaatcc atcaacagta ggaattataa caaatacagc tgtagtatct tcaactacag
     1921 cagacccaaa ccttaataat aatacatcta caatagagac agaagtgaat ttattagcag
     1981 atattttagt aatgaaaaca gcagaaccta attcagctgt tccaggtact ttattgagat
     2041 atactattca agtagaaaac ttaggaccag caaatgctga aaatgtaata ttaaatgatg
     2101 atattccagc ttctattata aatccagaat attcattgga tggaggagca agttttcaac
     2161 catggaatgg aagtcttaat ataggaactt taaactctgg aatttcatta acagttttaa
     2221 ttcaaggaac agttagttta aattcttcag aatatatagt aaatacagca acagtttctt
     2281 caactacacc tgacccagat ttaagcaaca atatatctac cattattaca ccagttaacc
     2341 cacaagcagg tatttctatt ataaaagtag ctgacgagga tgtagctgtt ccaggagaag
     2401 aatttgtata tacaattgaa atttttaatg aaggaccatc taatgctacg aatgtagttt
     2461 taacagatga tataccagat gttattttaa atccagaata ttcattggat ggaggagcaa
     2521 ctttccaacc atggaatgga agtcttaata taggtacagt tgcaccaggg caattaataa
     2581 gaattatcat aaagggatta gtaagttcaa ctgctacagg agatattact aatacagcag
     2641 aagtaagtgc agatgtacca gaaccagtta cggattcatc aacagtgaca actcctatag
     2701 ttccatcagc agatatagaa gtaataaaaa ctagcaatat ggatacagca gttccagaag
     2761 aaactttcag ttatactata acagttacaa atttaggacc atctgctgca caaagtatcg
     2821 ttttgacaga tgatatacca gatgttattt taaatccaga gtattcattg gatggaggag
     2881 taactttcca accatggaat ggaaatctta gtataggcac tttggatgct ggagaaataa
     2941 gaagtattat aataagagga acagtgagcc agacagcagt aggtacaatt ataaatacag
     3001 caacaataag ttcacctaca cctgacccaa atccagataa taatacttca acagatgaaa
     3061 cagatataag tccattagca gatatttctg tgataaaagg caacgaacca gttgctatac
     3121 caggaggaag atttatttat ggaattgaaa ttgcaaatgc aggaccatct tttgcagaga
     3181 acgtaacttt aacagataat ataccagctt ctattttaaa tccagagtac tcaatagata
     3241 atggagtgac tttccaacca tggaatggaa gccttaatat aggtacttta gatgctggag
     3301 agataagaaa tatcataata aggggaacag taagtcaaac agcaataggt acaattataa
     3361 atacagcaac agtaagttca actacacctg acccaaatct aaataacaat acttcaacat
     3421 cagaagcaga ggtaagttca tcagcagata tttctgtagt aaaacgaagc aatcagactg
     3481 ttgttgtacc aggagatgta ctagactata caattgaggt gagaaatgca ggaccgtcta
     3541 ctgctcagaa cgtaacttta acagataata taccagcttc tattttaagt ccagaatatt
     3601 caatagataa tggagtgact tttcaaccat ggaatggaag tcttagtata ggcactttag
     3661 atgctggaga gataagaaat atcataataa ggggaatagt aagtcaaaca gcaataggta
     3721 caattataaa tacagcaaca gtaagttcaa ctacacctga cccaaatcca gataataata
     3781 cttcaacatc agaaatagat ataagttcat cagcagatat ttctgtaata aaattagcaa
     3841 ataaaacaga agcatgtgta ggagagcaaa tagattttgt aatagtagta tcaaatgcag
     3901 gaccagaaaa tgctcaaaat gttactttaa tagacaatgt ttcagataag cttaagaaag
     3961 cagtattttc acttgataga ggtgtaagtt tccaaccatg gactggaagt cttaatatag
     4021 gtacactacc agctggaact ttaagagtga ttatattaag aggaattata aaatcaacat
     4081 gtcttgatag attaacaaat attgcagaag ttacttcaac aacaccagat tcaaacctta
     4141 acaataatat atcaagagtg caagtagaaa taaaacaatt ttgttgtaat gattgtggtt
     4201 gtaaagattg ttgctgtaat tgttgttgca atgattgtgg ttgtaaaaat tgttgctgta
     4261 attgttgtaa aaatgacttt tggtgttgat tttataaaat aattttgtat accttaaatt
     4321 aaactgaaat aaaaaataaa ttcacatatg agtaaaatat tttataaata ttaataaatt
     4381 ttctatcttt gatatggacc acat
//
LOCUS       DAJMZY010000181         4309 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.186, whole genome shotgun sequence.
ACCESSION   DAJMZY010000181 DAJMZY010000000
VERSION     DAJMZY010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4309)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4309)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4309
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.186"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            231..1310
                     /locus_tag="OE968_003640"
     CDS             231..1310
                     /locus_tag="OE968_003640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HCP7220869.1"
                     /translation="MPELLKNMYNRESLYEVAVAIQSVYNSFKVDEFIKSTMDETWNN
                     LELKARCRKISMSLGMYLPEDYKEALSILEKSVTGFYFAFFFPDFVEVYGQDDINWDL
                     SISALERNTEYWSSEFAVRAFIIKDEERMMAQMRKWSKHKSEHVRRLASEGCRPQLPW
                     GQAISKFKKDPTPVLPILEQLKTDTSTYVQKSVANNLNDISKTHPDLVISIAKDWYGK
                     NKSTNWIVKHGCRTLLKKGNRDVLALFGYDDTTSINLQDFTLETTSISIGEDLTFSFN
                     ILAKKATKTRLEYGIDYIKSNGKRNRKIFKISEVSLKENEKKSYMKKHSFADVSVRKH
                     YPGIHSIAIIINGIEKDKLDFELGI"
     gene            1634..2002
                     /locus_tag="OE968_003641"
     CDS             1634..2002
                     /locus_tag="OE968_003641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HCP7220870.1"
                     /translation="MDVYSFWNDTLAQDAVKIRKYFHENAYINWHDTNEHFTLEEFII
                     ANCEYPDKWNGKVEKVLEFGNLVITVTHVYAINKPLSFHVVSFISLKDDKIISIDEYW
                     GEDNDVPQWRLDKHIGKPIK"
     gene            2119..2922
                     /locus_tag="OE968_003642"
     CDS             2119..2922
                     /locus_tag="OE968_003642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HCP7220871.1"
                     /translation="MEEKYILSDRGKVYYWIKESNSVFAKNLIFLPGLTANHHLFDFQ
                     IQYFSKNHNVLVWDAPAHGKSRPYLDFSYSNLVEELKVILDKQNMKKVVLIGQSAGGF
                     VAQSFIVKYPNMVEGLMMIGTCPYGTDYYSKSDIFWLKQTEWMLKLFPDKFLRNIISK
                     MCGATSEGRRSMMKMLEGYEKKELCHLMYLGFAGFIPEIQDLNIHCPVCLVVGDKDKT
                     GKVRKYNEQWHNKTGYPLHIIKNASHNVNVDKPNELNQIMDIFIKQLNI"
     gene            3307..4197
                     /locus_tag="OE968_003643"
     CDS             3307..4197
                     /locus_tag="OE968_003643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HCP7220872.1"
                     /translation="MIESIPAKQILQKVKFDNTRWFGIDYNMNLYRGCSHGCIYCDSR
                     STIYNIENFDKVRYKENVIEILSKELRSKRKKGVVGIGAMSDTYNPFEKQLCITKQAL
                     DLISENHFGVSIDTKSSLVVRDIPILQKIKKNNSAIVKLTITTANDELSKKIEPYVNP
                     SSVRFEAVKELNDSGIFCGILLTPMLPFLTDTKDEIRAIVEKAHKANAKFIYCMYGVT
                     MRSGQREFFYEHLRDISPKLVFKYQKTYGLNYVCTVQNKDCCEKLLREECARYGILTD
                     MKDIIKAYKRSESYTQIKFF"
BASE COUNT         1649 a          471 c          806 g         1383 t
ORIGIN      
        1 cagtaaagta taaaattcta ttactataat aaaagataga actagaagtc tttatgaaag
       61 tgggaaaagt atttatataa ataaattcat atagtttata gtttaatagt aggaaatatc
      121 gtatgagtaa gaatattgta ttttacataa agatttagca atatgacaca ctgttgtcgt
      181 gttctgtagg atatgattaa taaatcagat atgaaaggag agtgagtaat atgccagaat
      241 tactaaaaaa tatgtataat cgtgagtcac tttatgaagt tgcagtagct atccaatcag
      301 tttacaactc atttaaggta gacgagttca taaaatctac aatggatgag acatggaata
      361 acttagaatt aaaagccaga tgtcgaaaga taagcatgag tttaggaatg tatttaccag
      421 aagactataa ggaagctctt tccattcttg aaaaatcagt tacaggtttt tattttgctt
      481 ttttctttcc agattttgtt gaagtttatg ggcaggacga cataaattgg gatttatcta
      541 taagtgcatt agaaagaaat actgagtatt ggtcttcaga atttgctgta agagcattta
      601 tcatcaagga tgaagaacgt atgatggcac agatgcgtaa atggtctaag cataagagcg
      661 aacatgtacg aagacttgca agtgaaggtt gtcgtcccca gttgccttgg ggacaagcaa
      721 tatccaaatt taaaaaagac cctacacctg tgctacctat attggagcaa cttaaaacag
      781 atacatcaac gtatgtacaa aagagtgttg ctaataatct aaatgatatc tcaaaaacac
      841 atccagattt agtcataagc attgcaaagg attggtacgg taaaaataaa tctactaact
      901 ggattgtaaa gcatggttgt agaactctac taaaaaaagg aaatcgtgat gtattagccc
      961 tttttggata tgatgatact acttctataa atcttcagga ctttacttta gaaacaacgt
     1021 ctatttctat tggagaggat ttaacttttt catttaatat tttagcaaaa aaagcgacaa
     1081 aaacaaggct cgagtacgga attgattata ttaaatctaa tggaaaaagg aataggaaga
     1141 tatttaaaat atcggaggtt tcattaaaag aaaatgagaa aaagtcatat atgaaaaaac
     1201 attcatttgc agatgtaagt gtaaggaaac attatccagg tatacactcg attgctatta
     1261 ttattaatgg tatagaaaaa gataaacttg attttgaatt aggtatataa ttttactaac
     1321 agaataatct atatcagata ctttgctaaa cttatataat atattttact aaatttatat
     1381 taggtagttt actacttgtt tactgaattt aaatacaaag aaatacaggt gctaatccct
     1441 gcccattaaa ggaatatgag cataacacaa aagtagaact tatcaattct gttacgggta
     1501 tagtagtaaa tccatagaat cacaattaga agatgaagtg taaaaaataa gttagtgttg
     1561 attttagttg ctagtgatat tgaatagtta tacaatagct atataaatta gaatttgtag
     1621 aggagaaatg taaatggatg tatatagttt ttggaatgac actttagcac aagatgctgt
     1681 taagataaga aaatattttc atgaaaatgc ttatattaat tggcatgata caaatgagca
     1741 ttttacttta gaagaattta ttattgcaaa ttgtgagtat cctgataaat ggaatggtaa
     1801 agtagaaaag gtgctagaat ttggaaattt agtaattaca gtgacacatg tttatgcaat
     1861 aaataaacca ctatcatttc atgtcgtttc atttatcagc cttaaagatg ataagattat
     1921 ttctattgat gaatattggg gagaggataa tgatgtgcca cagtggagat tagataaaca
     1981 tattggaaag ccaataaaat agtttttgtt ctgttttata actgaaattt tgataacatt
     2041 tgatattttg atttgtcatt ggtcaacata gtcgttagtg taataattta aaaaagtaga
     2101 atttggagag tgaacactat ggaagaaaaa tacatcttat ctgaccgagg gaaagtatat
     2161 tattggataa aagaaagtaa tagtgtgttt gcaaagaact taattttttt gccaggacta
     2221 acagcaaatc atcatctttt tgatttccaa atacagtact tttcaaaaaa tcataatgta
     2281 ttggtatggg acgctcctgc tcatggaaaa tcaagacctt acttagattt ctcatattct
     2341 aacttggtag aagaattgaa agtaatttta gataaacaaa atatgaaaaa ggttgtactt
     2401 atagggcaat cggcaggggg atttgtggca cagtccttta ttgtaaaata tccaaatatg
     2461 gtagaaggac taatgatgat tggaacttgt ccatatggaa ctgactatta tagtaagtca
     2521 gatattttct ggttaaaaca gactgaatgg atgttaaagt tattcccaga taaatttttg
     2581 cgaaacataa tatctaagat gtgtggagct acgtctgaag gcagaaggag tatgatgaaa
     2641 atgttagaag gctacgaaaa aaaagaactg tgtcatctca tgtatctggg atttgctggg
     2701 ttcataccag aaattcaaga cttaaatata cattgtccag tttgtttggt ggttggagat
     2761 aaagacaaga cgggtaaagt gagaaaatat aatgagcagt ggcacaacaa gactgggtat
     2821 ccattgcaca ttataaaaaa tgcttcacat aatgtaaatg tcgataaacc taatgaacta
     2881 aatcagatta tggatatatt tattaagcaa ttaaatatat aaaaattaca tactcattag
     2941 gtaaattatg tagtatatgt gtttatagat ggttatagaa ataaatatgt aataaactac
     3001 ttaacactta aaaagtggat ttgtccagag cataatacaa agcatgatat ataaattttt
     3061 aagcgaaata catcaaaaga agtattagaa ttagtggaga taaaacagct attagagatt
     3121 ataaataaat agttttaaag gtactacgaa tatagaggaa ggtaaatcat acgttattca
     3181 aggattataa atgattagtt taaaagtact atcggacagg tctctgcata tttaaacctt
     3241 agtaaaggta gttaaagtag tagtttaaaa actaaaaaat tatataaagg aattaggtat
     3301 aagaaaatga ttgagagtat accagcaaaa caaattttac aaaaagtgaa atttgacaat
     3361 acaagatggt ttggaattga ctataatatg aatctctatc gtggttgttc tcatggatgt
     3421 atatattgtg atagccgtag cacaatatac aacatagaga attttgacaa agttagatat
     3481 aaagaaaatg tgatagagat tttaagtaaa gaattgcgtt caaaaagaaa aaaaggggta
     3541 gtaggcattg gagctatgtc tgacacatat aatccttttg aaaagcaact ttgtattaca
     3601 aagcaggcac tagatttgat ttcggaaaat cattttggag tgtctattga tactaaaagt
     3661 agtttggtgg ttagagatat accgattttg cagaaaatta aaaaaaataa ttctgctatt
     3721 gtaaagttga ctataaccac tgcaaatgat gaattatcaa agaaaataga accttatgta
     3781 aatccaagtt ctgtacgatt tgaggcagtg aaagaactta atgattctgg aattttttgt
     3841 ggtatattat tgactcctat gcttccattt ttgactgata ctaaagatga aatacgagca
     3901 attgtagaaa aagcacacaa ggctaatgca aaatttattt attgtatgta tggtgtaaca
     3961 atgcgtagtg gtcagcgaga gtttttttat gagcatttaa gagatatatc accaaaattg
     4021 gtatttaaat atcagaaaac atatggttta aactatgtat gtactgtaca aaataaagat
     4081 tgttgtgaga agttgttaag agaagaatgt gcacgttatg gtattttgac ggatatgaaa
     4141 gatattataa aagcgtacaa gaggtcggag tcatatactc aaataaaatt tttttaagat
     4201 aggctttgga tgagatataa tagtggtgat tgatgtgttg atattatagt tgattgttag
     4261 agaggatatt atagatgaat attagtatta atattttagg taattgcta
//
LOCUS       DAJMZY010000182         4141 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.187, whole genome shotgun sequence.
ACCESSION   DAJMZY010000182 DAJMZY010000000
VERSION     DAJMZY010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4141)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4141)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4141
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.187"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            complement(<1..1114)
                     /locus_tag="OE968_003644"
     CDS             complement(<1..1114)
                     /locus_tag="OE968_003644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor domain-containing phosphodiesterase"
                     /protein_id="HCP7220873.1"
                     /translation="MTGRNKSFTLITILFLTSLFLTMGYIYIEDTKHLLMSEAKIHIK
                     EVAVQGSQLAQRQIEKDLDVLNIFSNYYASNPDIPNEEKMKNLLDEMENQKFYTMAIV
                     DINGNAENTKGDKFSVKDREFFKNSIKGKKYVSSPYVDEVNKSIKKIAISVPLLNNDK
                     VVGVLYCTYNINTLMKLINISFYENNSISYVVKNDGTIILHPQGDSLSKNIYKLLEQD
                     NDIQEVNRLKKELQENKTGATVLNMLEERRYLGYATMDNGNSENNYIKDWNLIFSIPE
                     TVVFSNSKQIINRAVYAVLSIVLIFVAIIFYIIYIKKSNEKEILSLAYEDKVTYIGNQ
                     NKFYRECSKYLLDKPSLNYIIVYFDINNFKMINDTFG"
     gene            complement(1390..4044)
                     /gene="adhE"
                     /locus_tag="OE968_003645"
                     /gene_synonym="adhC"
     CDS             complement(1390..4044)
                     /gene="adhE"
                     /locus_tag="OE968_003645"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HCP7220874.1"
                     /translation="MAHKEQVIIENKKENEVMSVGLDTVNNVESLVKKLAKIREAQKI
                     FATYSQEQVDKIFLAASLAANKQRVPLAIMAQKETGMGIAEDKVIKNHYASEYIYNAY
                     KETKTCGVIEKDEAFGMTKIAEPIGVIAAVVPTTNPTSTAIFKALLALKTRNGIIFSP
                     HPRAKNSTIEAAKVVLEAAVLAGAPEGIIGWIDEPSLELTTTVMKEVDLTLATGGPGM
                     VKSAYSSGKPAIGVGAGNTPAIIDDSADIKTAVNSILVSKTFDNGMICASEQSVIVLE
                     NIYNEVKKEFKERGAYLLDKDETEKIRNIILVNGGLNSKIVGQTACTIAKLAGFEVPV
                     DTKVLIGEVESVEIEEAFAHEKLSPVLAMYKASDFDDAVRKAEKLVEDGGFGHTSSLY
                     IDDVNQREKLDKFTSAMKTCRILINTPSSQGGIGDLYNFKLAPSLTLGCGSWGGNSVS
                     ENVGVKHLLNIKTVAERRENMLWFRAPEKVYFKKGCLGVALKELKDVMNKKRAFIVTD
                     TFLYNNGYTKAVTDLLDEMNIKYTTFFEVEPDPTLECAKIGAKAMREFNPDVIISIGG
                     GSAMDAGKIMWTLYEHPDVDFQDLAMRFMDIRKRVYTFPKMGEKANFVAIPTSAGTGS
                     EVTPFAVITDQDTGVKYPLADYELMPNMAIVDSDMMMNMPKSLTSASGIDALTHALEA
                     YVSMLATDYTNGLALQAIKSIFEYLPRAYDNGAKDPEAREKMANASTMAGMAFANAFL
                     GVCHSMAHKLGAFHHVPHGVANALLITEVMKFNSSDAPKKMGAFSQYKYPEALKRYAE
                     IASFLGLKGNSDEEKFQSLLVAIEDLKLKVGIPKSIKEFGVEESKFMDSIDEMVIQAF
                     DDQCTGANPRYPLMNEIKDMYLNSYYGR"
BASE COUNT         1318 a          738 c          468 g         1617 t
ORIGIN      
        1 atccaaaagt atcattaatc atcttaaagt tattaatatc aaaatatact ataatataat
       61 ttaaagatgg tttatctaaa agatacttac tacattctct ataaaattta ttttgatttc
      121 ctatatatgt aactttatct tcataagcca aacttaatat ttctttttca ttagattttt
      181 ttatataaat tatataaaaa ataattgcaa caaatattaa tacaatagat aacactgcat
      241 atacagctct gttgattatt tgttttgaat tactaaatac aacagtttct ggaattgaaa
      301 aaattaaatt ccagtctttt atataattat tttcactatt cccattatcc atagtggcat
      361 accctaaata tcttctttct tccaacatat ttaatacagt tgcacctgtt ttattttctt
      421 gcaattcttt ttttaatcta tttacttctt gaatatcatt atcctgttct aacaatttat
      481 aaatattttt tgataggcta tccccttgtg gatgaaggat aattgtacca tcatttttta
      541 caacataaga tatactatta ttttcataaa aagatatatt aataagtttc atcagagtat
      601 tgatattgta agtacaatat aaaactccaa ctactttatc attatttaat aatggtactg
      661 aaatagcaat cttctttata gacttattta cttcatcaac atatggactt gaaacatact
      721 tcttaccttt aattgagttt ttgaaaaatt ctctatcttt cactgaaaac ttatcacctt
      781 tggtattttc agcattacca tttatatcaa ctattgccat agtgtaaaat ttttgatttt
      841 ccatttcatc taaaagattt ttcatttttt cctcattagg tatatctgga tttgaagcat
      901 aatagttaga aaaaatattt aaaacatcta aatctttttc aatttgtctt tgtgctagtt
      961 gagagccttg tactgcaact tcttttatat gtatttttgc ctctgacata agaagatgtt
     1021 ttgtatcttc tatatagata taccccattg tcaaaaataa tgatgttaaa aaaagaattg
     1081 taattaatgt aaaactttta tttctccctg tcattcgact cctcccctaa ttagtcaata
     1141 cttcatatag ataatatatc ctttttatac caattcatca tttatattgt atataactat
     1201 tcttaaatgt tacacataaa atcaacataa taaccataaa aacattcttt tattattata
     1261 ataacactat ttaattgaat tttaaattaa agaataaaaa ctatccattt tctcaaacaa
     1321 aaaaactctt atacaataaa actttgtttt atgtataaga gtttttattt tatctatttt
     1381 atagcaaact tatcttccat aatatgaatt taaatacata tcttttattt cattcataag
     1441 tggatatctt ggatttgctc ctgtacattg gtcatcaaat gcttgaatta ccatttcatc
     1501 tattgaatcc ataaacttag attcttcaac gccaaactct tttatagatt taggaatacc
     1561 aactttaagt tttaaatctt caatagctac caataaactt tggaatttct cttcatcaga
     1621 atttcctttt aatcctaaaa atgaagctat ttcagcatat ctctttaatg cttctggata
     1681 tttatattga gagaatgctc ccattttctt tggtgcatct gaagaattaa atttcataac
     1741 ttctgttatc aaaagagcat ttgcaacacc atgtggtaca tggtggaaag cacctaattt
     1801 atgagccata gagtgacaaa cacccaaaaa tgcatttgca aaagccatac ctgccattgt
     1861 agaagcattt gccatttttt ctctagcttc tgggtctttt gcaccattat catatgcacg
     1921 tggaagatat tcaaatatac tcttaatagc ttgtaaagct aatccatttg tataatcggt
     1981 tgcaagcata gatacatatg cttctaatgc atgagttaaa gcatctatac cagaagcaga
     2041 tgttaagctt tttggcatat tcatcatcat atcagaatca actatagcca tatttggcat
     2101 cagttcataa tctgctaatg gatattttac tcctgtatct tggtcagtta taacagcaaa
     2161 tggtgttact tctgaaccag tacctgctga tgttggtata gctacaaaat tagctttttc
     2221 acccatttta gggaatgtat ataccctttt tcttatatcc ataaatctca tagctaggtc
     2281 ttggaaatct acatctggat gctcatacaa tgtccacatt atctttcctg catccattgc
     2341 acttcctcca cctatagata ttattacatc tggattaaat tctctcatag ctttagcgcc
     2401 tatcttagca cattccaaag ttgggtctgg ttctacttca aagaatgtag tgtacttaat
     2461 attcatttca tctaataaat cagtaactgc tttagtatat ccattattgt aaaggaatgt
     2521 atctgttaca ataaaagctc tcttcttatt cattacatct ttaagttctt ttaatgctac
     2581 tcctaaacaa ccttttttga aataaacttt ttctggtgct ctaaaccaaa gcatattttc
     2641 tctcctctca gctactgttt taatattaag taaatgctta actcctacat tttcagatac
     2701 tgaatttcca ccccaagacc cacatcctaa agtaagagaa ggagctagtt taaaattata
     2761 taagtcccct ataccacctt gagaagaagg agtattaatt aaaattctac aagttttcat
     2821 ggctgaagta aacttatcaa gtttttctct ttgatttaca tcatcaatat ataatgaaga
     2881 tgtatgccca aatccaccat cttctactaa tttttctgct tttctaactg catcatcaaa
     2941 atcacttgcc ttgtacattg caagtactgg tgaaagtttc tcatgagcaa aagcttcttc
     3001 tatttcaact gattctactt cacctattaa aaccttagta tctactggga cttcaaagcc
     3061 tgcaagtttt gctatagtac aagctgtttg cccaactatt ttagaattta atcctccatt
     3121 tactaaaatt atatttctta ttttttctgt ttcatcttta tctaataaat aagcaccacg
     3181 ctctttaaat tcttttttga cttcattgta tatattttct aatactataa ccgattgttc
     3241 agaagcacat atcataccat tgtcaaaagt cttagataca agaattgagt ttacagcagt
     3301 ttttatatct gcactatcat caattattgc tggagtatta cctgcaccaa ctccaatagc
     3361 tggttttcca gatgaatatg ctgatttaac cattccagga cctcctgtag caagggtcaa
     3421 atccacttct ttcataacag ttgtagttaa ttctaaagat ggctcatcta tccatcctat
     3481 tataccttca ggagctccag ctaaaacagc agcctcaaga acaacttttg cagcctctat
     3541 agtagaattt tttgctcttg gatgtggaga gaaaattatt ccatttctag tttttaaagc
     3601 taaaagtgct ttaaagatag cagtagaagt tggattagtt gtaggtacaa ctgctgcaat
     3661 aacacctatt ggttcagcaa ttttagtcat accaaatgct tcgtctttct ctataacacc
     3721 acaagtttta gtttctttat atgcattata tatatactct gaggcataat gattctttat
     3781 aaccttatct tcagcaattc ccataccagt ttctttttgt gccattatag ctagaggaac
     3841 tctttgctta ttagctgcca aagatgctgc taaaaaaatt ttatctacct gctcttgact
     3901 atatgtagca aatatttttt gagcttctct gatttttgct agttttttaa ctaagctttc
     3961 aacgttattt acagtatcta aaccaactga cataacttca ttttcttttt tattttctat
     4021 tattacttgt tctttatgag ccattttaac aacctcctga gatagttttt tatttattat
     4081 gttaatttat taacattata gcatttactt ttcctatttt caagttattt ttttaacatt
     4141 t
//
LOCUS       DAJMZY010000183         4106 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.188, whole genome shotgun sequence.
ACCESSION   DAJMZY010000183 DAJMZY010000000
VERSION     DAJMZY010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4106)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4106)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4106
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.188"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            6..404
                     /locus_tag="OE968_003646"
     CDS             6..404
                     /locus_tag="OE968_003646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HCP7220875.1"
                     /translation="MIKKIEHVVITNNNIENYINFYKKFGFSSKEMSKNYKLNARNIK
                     INLNIKGYKFLPYVKNLQASRDNLCFKINTNIDEPKKYLEQNEIQIKRGIVECTGVFG
                     NMKSIYLKKTNGNLIELSNHRITESKPWKI"
     gene            392..1330
                     /locus_tag="OE968_003647"
     CDS             392..1330
                     /locus_tag="OE968_003647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HCP7220876.1"
                     /translation="MENLILSINVVLPLFLTMSLGYVLKKLGLFDTHTLNKMNNVCFK
                     SFLPLLLFFNIYNTDLDGSLNFRLMAVAVIIIFSIFLILVFIIPKIEKDNKTRGALIQ
                     GVFRSNFVIFGIPVTISLFGDKSIGVTSLLIAVIVPMFNVLSVVILEIFRGGKVNIKH
                     MIKSVLTNPLIIASFIGLTMLILNINIPTFLHKTIGDISKIATPLSLIILGGSFSFSA
                     IKGHINPIILGVCGKLILVPAIFLPISIFLGFRNVELASLMIMLSAPTAVSSFTMAQQ
                     MDSDSELAGQIVVFTSGFSIITVFLIIFILKQNNLI"
     gene            complement(1714..1938)
                     /gene="secG"
                     /locus_tag="OE968_003648"
     CDS             complement(1714..1938)
                     /gene="secG"
                     /locus_tag="OE968_003648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HCP7220877.1"
                     /translation="MSNILMGVQVVLGILLVISIMPQDSKNALPSEFGGEGSQAYFKP
                     KGKQAFLARVTKITAVLFFINALALLIVKK"
     gene            complement(2531..3823)
                     /gene="eno"
                     /locus_tag="OE968_003649"
     CDS             complement(2531..3823)
                     /gene="eno"
                     /locus_tag="OE968_003649"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HCP7220878.1"
                     /translation="MSVIELVYAREVLDSRGNPTVEVEVVLEDGAMGRAIVPSGASTG
                     AFEAVELRDGDKGRYLGKGVETAVANVNEIIAPEIEGMDAFDQPAIDAIMIELDGTPN
                     KGKLGANAILGVSMAVARAAADEIGLPLFQYLGGVNAKQLPVPMMNILNGGEHADNNV
                     DVQEFMILPVGACCFKEGLRMGAEVFHSLKKVLGEKGLACGVGDEGGFAPNLGSNREA
                     LELIVEAITKAGYKPGEDVMLGLDVAATEMYNKETKKYVLAGEGKELTAAEMVALYED
                     WSNNFPIITIEDGLDEEDWDGWKLLTEKLGNKLQLVGDDLFVTNTERLEKGIENGVAN
                     SILVKVNQIGTITETLDAIEMAKRAGYTAVISHRSGETEDSTIADLAVAVNAGQIKTG
                     APSRTDRVAKYNQLLRIEEMVGEQARYCGLKSFYNLKK"
BASE COUNT         1417 a          659 c          459 g         1571 t
ORIGIN      
        1 ttgccatgat aaaaaaaata gaacatgtgg tcattactaa taataatata gaaaattata
       61 tcaattttta taaaaaattt ggtttttcat ctaaagaaat gagcaaaaat tataaactta
      121 atgctagaaa tattaagata aatcttaaca taaaaggtta taaattttta ccttatgtta
      181 aaaatttaca agcaagtaga gataacttat gttttaaaat aaacacaaat attgatgagc
      241 caaaaaaata cttagaacaa aatgagattc aaattaagcg aggaattgta gaatgtacag
      301 gtgtctttgg taatatgaaa tctatttatt tgaaaaaaac taatggaaat ttaattgaat
      361 tatcaaatca tagaatcacg gagagtaaac cttggaaaat ttaatcctat caataaatgt
      421 tgttcttcct ttgtttctca caatgtcact tggatatgtt ctaaaaaaat taggtctatt
      481 tgatactcat actttaaata aaatgaataa tgtctgcttc aagtctttct tgccattatt
      541 attatttttt aatatataca atacagattt agatggttct cttaatttta ggcttatggc
      601 tgtagctgtt ataattattt tttcaatctt cttaatctta gtctttatta ttcctaaaat
      661 tgaaaaagat aataagacaa ggggtgcatt aatacaaggt gtatttcgta gcaatttcgt
      721 tatatttggt attcctgtga caatttcact atttggcgat aagagtattg gagtcacatc
      781 tttattaatt gcagttattg tacctatgtt taatgtatta tctgttgtaa ttcttgaaat
      841 ttttagaggt ggcaaagtaa atataaaaca tatgattaaa agcgtcttaa caaatccact
      901 cataatcgcc tcttttatag gattgacaat gctaatttta aatattaata tacctacatt
      961 tttacacaaa actattggtg atatttctaa aatagctact cctttatcac ttataattct
     1021 aggtggctct tttagttttt ctgctataaa ggggcatata aaccccatta tattgggcgt
     1081 atgtggaaaa cttatacttg tacctgctat atttttacca attagcattt ttcttggatt
     1141 tagaaatgta gaattagctt cacttatgat aatgttatct gctccaactg cagtttcttc
     1201 atttacaatg gcacaacaga tggattctga cagtgaatta gctggacaaa ttgtagtatt
     1261 tacttctgga ttttctataa ttacagtatt tttaataata tttattttaa agcagaataa
     1321 tcttatttaa tgatatttga taacacaaat tggtattatg agaaacatat ataaaatcga
     1381 tttaattgcg taaaaacata ttattatact atttttacta tataatataa ctttgtgtat
     1441 attatctcat taaacatggt gaaagtagtg ttgctatata ttttttagtt tgaaaaaaat
     1501 atataaatac aaacaatata taaatacaaa taataaacgc caacaaatag tcaatctata
     1561 aaataaaaac tggactaatc atataaaatc attagtccag cttttatttt acgtactttt
     1621 tatgttgatg tacttttatt aaaaactaaa tttaattttt aaatgtctag caaatgcact
     1681 aattaaataa tggccagtta ttcaacaata tcactacttc ttaactataa gtaatgccaa
     1741 tgcatttata aaaaataata ctgctgttat ctttgtaact ctagcaagaa atgcttgttt
     1801 tccttttggt ttaaagtaag cttggcttcc ttctccacca aattctgaag gtaaagcatt
     1861 cttagaatct tgaggcatta tgctaattac tagtaaaatc cctagtacta cttgcacacc
     1921 cattaaaatg ttgctcattc ttgcccctcc tatctgttta ttacttaaat ttcattactc
     1981 tttagtgtat cacaataata tagccatttc aagactatta tgctataaat aacatacaaa
     2041 aaaatatatt gttactataa tatattacta tattctcaat ataaaaatga ataaaactta
     2101 gaagagaaaa ctatttaaat taatgcataa attaacactt aaaataatct actctcattg
     2161 tatatattat aaatagccac caaaataaaa caatcatttt aaaatattga tataactttt
     2221 aatttcaaca taatttaaaa taaataatcc acatttagca ataatacttt aatgacaatt
     2281 atgattaaat caaaatatgt cttcactttt attttttaat aaaaacctcc tatgcaatta
     2341 gataaaaatg agatagaaac atttattcat attttttctg aatctatgaa taaaattaag
     2401 taataaaata taaaaaagga taagtgaatt gaaaaatcaa ttaacactta tctcttttat
     2461 atcttataag atgagcttaa atatcttata ttctctcttc attaatcttt tttagtaacc
     2521 attttaataa ctattttttt aagttataga aagattttaa tccacaatat ctagcttgct
     2581 ctccaaccat ttcttctatt cttaataatt ggttgtactt agcaactcta tcagttcttg
     2641 atggagcacc agtttttatt tgaccagcat ttactgcaac agctaaatct gctatagtag
     2701 aatcttcagt ttctcctgat ctgtgagata taacagcagt atatcctgct ctcttagcca
     2761 tttctatagc atctaaagtt tcagttattg tacctatttg attaacttta actaatatag
     2821 agttagctac tccattttca attccttttt ctaatctctc tgtgttagta acaaataagt
     2881 cgtcaccaac taattgtaat ttatttccta atttttcagt taataatttc catccatccc
     2941 aatcttcttc gtctaaacca tcttctatag ttattattgg gaagttgttt gaccaatctt
     3001 catataaagc aaccatttca gcagcagtta actcttttcc ttctcctgct aaaacgtatt
     3061 ttttagtttc tttgttgtac atttctgtag cagcaacgtc aagacctaac ataacgtctt
     3121 cacctggctt atatccagct tttgttatag cttcaactat taattctaaa gcttctctgt
     3181 ttgaacctaa gtttggagca aatccacctt cgtcacctac accacaagct aatccttttt
     3241 ctcctaaaac tttctttaac gaatggaata cttctgctcc cattcttaaa ccttctttga
     3301 aacaacaagc tcctactggt aatatcataa attcttgaac atcaacgttg ttatcagcat
     3361 gctctccacc gtttaatatg ttcatcattg gaacaggtaa ttgtttagca tttactccac
     3421 ctaggtattg gaataatggt aaacctattt catcagcagc tgctctagct actgccattg
     3481 aaacacctaa tatagcatta gctcctaatt tacctttgtt tggagttcca tctaattcta
     3541 tcatgattgc atctatagct ggttggtcaa atgcatccat tccttctatt tcaggtgcta
     3601 ttatttcatt tacgttagca acagctgttt ctacaccttt tcctaagtat cttcccttat
     3661 ctccatctct taattcaaca gcttcaaaag ctcctgtaga tgctcctgat ggaactattg
     3721 ctcttcccat tgctccatct tctaatacta cttcaacttc tacagttgga tttcctcttg
     3781 agtctaatac ttctctagca tatactaatt caataactga catttgtata tctcccttcg
     3841 attttctatt agttaaattt tcatttactg taaacatccg tctactattt taatctactt
     3901 tctatattat agtacataaa gttgcttttg aaaattaggt acaaatttat ttgatgggta
     3961 aatttgtaaa agttcctatt tttattttat tttttataat attttaattt atataatata
     4021 aaaaaacttg tctaaaatcc aaaaccaatc ttaaatacac aaatattata actagattta
     4081 aaacattaaa cataaaatgt acaact
//
LOCUS       DAJMZY010000184         4078 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.189, whole genome shotgun sequence.
ACCESSION   DAJMZY010000184 DAJMZY010000000
VERSION     DAJMZY010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4078)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4078)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4078
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.189"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            <1..1226
                     /locus_tag="OE968_003650"
     CDS             <1..1226
                     /locus_tag="OE968_003650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220879.1"
                     /translation="CIYLDKKYRCNGKIYYKMTPPISISFKADIGCVEEIDNEDDNLA
                     LDYDNAILEVHGYKIISITINTLSEFSVEGYINDDCIKSKNSYVEYVDFNIINLDKIP
                     GKLIKYNDKVYAGRIEFDINDYVVTIDKRYDYRKELKSELKSKSGAIITHIGRIRRKD
                     GRIFRTNNTINLLDRISTALSFMCGRYVGFCLAKGYRSGNEVYRIWNENQISPFRYVP
                     TWSDTLSNYYNMEKYISLMCKKLEDFYYGSAIKSVVDWYIESLGSATMENNIISVQIA
                     LETLSYVILVEQNKILTDEVFDCNLASKNIRLLLDTCKIPYGKHELNIFDNIIKNKFD
                     DGVDLVIYLRNSIVHPSRKTHRAVLEVEDIWNIISIGTRYIELVLLFILGYRGEYSNR
                     LVERCYGEVEVVPWN"
     misc_binding    1312..1574
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            1700..2503
                     /locus_tag="OE968_003651"
     CDS             1700..2503
                     /locus_tag="OE968_003651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HCP7220880.1"
                     /translation="MKNILKKVGIFTIMLGLLGGVVGCSKPDNEKDKDASKESKKEVV
                     VGFDNTFVPMGFLDEKGDTVGFDVDLAKETFKRLGMEVKFQPIDWSMKETELNDSKTV
                     DVLWNGYSITDERKKIVSYTEPYLQNKQIIVTLSDSKINSKADLKDKEVGTQQGSTAL
                     DAVEKDKDFMNSLKGGAPVLYDTYDKALRDLEIGRTSAVVGDEVLIRYYMGQKGEDKY
                     KVLKDDFGLEDYVVATSKENPELCEKINETLKEMKKDGTFDKIYDKWFK"
     gene            2541..3152
                     /locus_tag="OE968_003652"
     CDS             2541..3152
                     /locus_tag="OE968_003652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HCP7220881.1"
                     /translation="MLQGLEIVIAMFCITLIVSIPLGIGVAFLRLSKNKLVSGITQCY
                     ILIMRGTPLLLQMIVIFYGLPLLGIVFDRFTAGVVAFFLNYAAYFAEIFRGGIQSIDR
                     GQYEASKVLGFDKFTMYKRVIFPQVFKRILAPISNEVITLVKDTSLVYILGLNDILRI
                     SQIAMNREASLLPLFEAGAIYLIFVAILTKGFELLEKKYSYYR"
     gene            3184..3855
                     /locus_tag="OE968_003653"
     CDS             3184..3855
                     /locus_tag="OE968_003653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HCP7220882.1"
                     /translation="MLKIKNLNKSFKKNRVLKDISFELEEGQIGVLLGKSGAGKTTIL
                     RCINGLEEFDSGEIIIDNEVIKNKRDMAKIRGKIGMVFQNFNLFPHMTVLENIIESPV
                     NVFKVPRKEAEERARELLRLVDLEDKLNSYPFELSGGQQQRVAIARSCALMPKVLCFD
                     EPTSALDIDTIQRVVNIMNRLKDKGMTILIITHDVVFSNNVADKIISIKDGIVENVQI
                     KEKIV"
BASE COUNT         1614 a          388 c          750 g         1326 t
ORIGIN      
        1 tttgcatata tttagataaa aaatatagat gtaatgggaa aatttattat aaaatgacac
       61 ctccaatatc tataagtttt aaagcagaca taggttgtgt tgaagagata gacaatgaag
      121 atgacaattt agctttagat tatgataatg ctattcttga agttcatgga tataaaatta
      181 tttctataac aataaatact ttaagtgaat ttagtgtaga aggttatatc aatgatgact
      241 gcataaaatc taagaactcc tatgttgaat atgtagattt taatataata aacttagata
      301 aaatacctgg aaaactcatt aaatacaatg ataaggtata cgcaggtaga attgaatttg
      361 atataaatga ttatgttgta actatagaca agcgatatga ttatagaaaa gaattaaaat
      421 cagaattaaa gtctaaatct ggagcaataa taactcatat aggtaggatt agaagaaaag
      481 atggtagaat ttttagaaca aataatacaa taaatctttt agataggata tcaacagctt
      541 tgagttttat gtgtggaaga tatgtagggt tttgtttggc caaagggtat agaagtggta
      601 atgaagttta tagaatatgg aatgaaaatc aaatatctcc ttttagatat gtaccaacat
      661 ggtcagatac actttcaaat tattataata tggaaaaata tataagcctt atgtgtaaaa
      721 agctagaaga tttttattat ggttctgcta taaagagtgt tgttgattgg tacatagaat
      781 ctcttggaag tgctaccatg gaaaacaata taatatctgt acaaattgca cttgaaactt
      841 tgtcatatgt aattctagtg gaacaaaata agatacttac agatgaagta tttgactgta
      901 atttggcatc taaaaatata agactcttac ttgatacatg taagatacca tatggtaaac
      961 atgaattaaa tatatttgat aatataataa aaaataaatt tgatgatgga gtggatttag
     1021 ttatttattt aagaaatagc atagttcatc caagtagaaa gactcataga gctgtgttag
     1081 aggttgaaga tatttggaat ataatttcaa taggaacgag atatattgaa cttgttttac
     1141 tctttatttt aggttataga ggagaatatt caaacagatt agtagaaaga tgttatggtg
     1201 aagtggaagt tgtaccttgg aactagattt ttatatttat tttaaaatat atattgacat
     1261 atattgcctt atgctataaa atcaatatca taataataat tcagaataac attaaatgct
     1321 aagaaaagaa atagtaaaag tagttaatct taaacagaga gtttccgatt ggtgagagga
     1381 gcaatagatt ttactttgaa cacatctttg agcaggactc tgaaagagta gaaatacttt
     1441 attaggagat ttccggaatc cttgcacccg ttatagtgct agagtataat aattttattg
     1501 tacttaaaga ggttagtgtc gtgaggcatt aatgaacaga ggtggaacca cgagagttaa
     1561 ctcccgtcct ctagcagaag ctagaggcgg gagtttttta atataatttt ttaagcgcgc
     1621 agagaattat attgcaatag atacactttt taaaaaataa tcaaaatatt ttaaaaatta
     1681 aaaggcgagg gagaatatta tgaaaaatat attaaaaaaa gtaggaatat ttacaattat
     1741 gttaggttta ttaggtggag ttgtaggttg ttcaaaacca gataatgaaa aagataagga
     1801 tgcttcaaag gaatctaaaa aagaagtagt tgtagggttt gataatacgt ttgtaccaat
     1861 gggattttta gatgaaaagg gagatacagt aggatttgac gtagacttag ctaaagaaac
     1921 atttaaaaga cttggaatgg aagttaagtt tcagcctata gattggtcaa tgaaagaaac
     1981 tgaattaaat gattcaaaaa ctgtagatgt attatggaat ggatattcta taacagacga
     2041 aagaaagaaa atagtatcat atacagaacc atatttacaa aataagcaga taatagttac
     2101 tctaagtgac tcaaaaataa attcaaaagc tgatttaaaa gataaagaag ttggaacaca
     2161 acaaggttca acagcacttg atgcagtgga aaaggataaa gattttatga atagcttaaa
     2221 aggtggagca ccagttcttt atgatactta tgataaagca cttagagatt tagagatagg
     2281 tagaactagt gcagttgttg gtgatgaagt tttaattaga tactatatgg gacaaaaggg
     2341 tgaagacaaa tacaaggtat taaaagacga ttttggatta gaagattatg ttgtagcaac
     2401 ttctaaagaa aatccagaac tttgtgagaa aataaatgaa acattaaaag aaatgaaaaa
     2461 agatggaact tttgacaaga tttatgataa gtggtttaaa tagaagataa gttagctgtt
     2521 aagaaggggg cactaaaggc atgttacaag gtttagagat agttatagca atgttttgta
     2581 taacattgat agtatcaatt ccattgggga ttggagttgc atttttaaga ttatcaaaga
     2641 ataaattagt aagtggtatt acacaatgtt atatattgat aatgagaggt acacctttac
     2701 ttttgcaaat gatagtcata ttttacggat tacctctttt aggaattgta tttgacagat
     2761 ttacagctgg agtagtagct ttcttcttaa attatgcagc atattttgca gaaatattta
     2821 gaggtggaat acagtcaatc gatagaggac aatatgaagc ttcaaaagta ctaggatttg
     2881 ataagtttac tatgtataag agagtaatct ttccacaagt ttttaaaaga atactagcac
     2941 ctatttcaaa tgaagtaatc acattagtaa aagatacatc tttagtatat atattaggat
     3001 taaatgatat tttaagaata tctcaaatag caatgaacag ggaagcaagt ctgttaccat
     3061 tatttgaggc aggagcgata tatcttatat ttgtagctat acttactaag ggatttgaat
     3121 tacttgaaaa aaaatattct tattatagat aaagttacaa tattatagga ggaggttttt
     3181 tatatgttga aaatcaaaaa cttaaataaa tcatttaaaa aaaatagagt acttaaagat
     3241 atttcttttg agttagaaga aggtcagatt ggagttttac ttggtaagtc tggtgcagga
     3301 aagaccacaa tattaaggtg tataaatggt cttgaagaat ttgatagtgg agagattata
     3361 atagataatg aggtaataaa aaataagaga gatatggcaa aaatacgagg aaaaataggt
     3421 atggtttttc aaaatttcaa cttatttcct catatgacag tccttgaaaa tataattgaa
     3481 tccccagtta atgtttttaa agttcctaga aaagaggctg aagagagggc tagagaactt
     3541 ttaagattag ttgatttaga agataaatta aattcttatc catttgaatt gtcaggagga
     3601 cagcaacaga gagttgctat agctaggtca tgtgcattga tgccaaaagt cctttgtttt
     3661 gatgaaccta cttctgcact tgatattgat actattcaaa gagtagtcaa tataatgaac
     3721 agacttaaag acaaaggtat gacaatatta ataattacac atgatgttgt cttctcaaat
     3781 aatgttgcag ataaaattat aagtataaaa gatggtatag tagaaaatgt tcaaataaaa
     3841 gaaaaaattg tttagagttt tataaatata aactagggta gaattttata atataaataa
     3901 agggcaagta aaatcaaata tactatgccc ttttgttatc tcaaaattta atcttatatt
     3961 ttatgtttaa gttacattat aatttataat aaaaataaaa ggactattta aatatataat
     4021 gtgaataatg tttaataatt tgaaatatga taatttttta tgttgaaagc ttataatg
//
LOCUS       DAJMZY010000185         3915 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.190, whole genome shotgun sequence.
ACCESSION   DAJMZY010000185 DAJMZY010000000
VERSION     DAJMZY010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3915)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3915)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3915
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.190"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            67..939
                     /locus_tag="OE968_003654"
     CDS             67..939
                     /locus_tag="OE968_003654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCP7220883.1"
                     /translation="MEMKIAVSNLSKRFGKKQALDNINLEIDSGMFGLLGRNGAGKTT
                     FMRILATLLSKTEGSIHMCGVPIENTKEIRNMVGYLPQDFSMYPNMTVYKAMDYLAVL
                     SDIPLRKRRKIIAKLLSKVNLTNYQNVKVKSLSGGMNRRLGIAQALIHNPRVLIVDEP
                     TAGLDPEERIRFRNLLCEIANDRIVILSTHIVGDIEATCENVAILNSGKVIYNGSTEA
                     LAKLAEGKVYSIEVDKKDIENIKSRFIVIGMLTHGGKAILRIISDDKPFETAVNCNPT
                     IEDGYMLIMGGDNI"
     gene            936..2225
                     /locus_tag="OE968_003655"
     CDS             936..2225
                     /locus_tag="OE968_003655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCP7220884.1"
                     /translation="MNLFIKECKNILKSMIYYIFIVVLVFFYISQLGSSVSNDVSKNI
                     PNDGNPLVAPQKVENIEEYYSVHNQYPYGQKESMKTEKVIPNATINLIREYQKNTYTT
                     YPTGVVKYIKLDQNKTKTIEKYIEEITGKSISEINSLWKTDESIKIDYSKVSLERFEE
                     IMQRVDDILGGGSAYAFDKLQRFGVVPVTYDEAMKNYNYTIQKDKVSNGYARIFCDYI
                     GIVLSIFPVFVAVFMSLKDKRSRMREIIYSKQVSSCKIVLSRYFALVFMMILPVLILG
                     MKDLLPLIFFAKDKGISIDNLAFIKYTLWWILPTLMIVTAVGMSITILTDTPVAIIVQ
                     LIWWLYSINSTGLKGDYSTMGLMIRHNSVLNGDIIIQNFNQIMINRIVISLGALVLVL
                     LAIFLYEQKRRGNLDVWAKFSKLFSSNKRKLQIKHFN"
     gene            2155..2799
                     /locus_tag="OE968_003656"
     CDS             2155..2799
                     /locus_tag="OE968_003656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCP7220885.1"
                     /translation="MFGQSFQNCLVLIKENFKLSTLTNLICSIILLCMIPLIQGVANL
                     DRISTAICLENYVAIIGIVMLVPVFSLEQSKEIDEIVSSKALSQVIVQLIRILMSIIG
                     IVVLIIGFVNVLIYLGCNFPVVEYIIGSFASAMFIGSLGMFFSNLFNNTIIGYMISIG
                     YLILNMMTKGKYVGKFFIMSMSQGSFDEKYWLILGSVVLIIASLLIKPVKRKIR"
     gene            complement(3066..3529)
                     /locus_tag="OE968_003657"
                     /pseudo
     CDS             complement(3066..3529)
                     /locus_tag="OE968_003657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861860.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
BASE COUNT         1466 a          463 c          601 g         1385 t
ORIGIN      
        1 tgaaaataca gtaaaaattt ataaaaataa aattctataa aattgtttct gggggtgtat
       61 ttatatatgg aaatgaaaat agcagtatcc aatcttagta aaagatttgg gaaaaaacaa
      121 gctcttgata atataaatct tgaaatcgac agtggtatgt ttggtctttt aggaagaaat
      181 ggagcaggaa aaaccacatt tatgagaatt ttagccactt tattatcaaa aacagaaggt
      241 tcaatacata tgtgtggagt tcctattgag aatactaagg aaattagaaa tatggttggt
      301 tatttgccac aagacttttc aatgtatcct aacatgacag tatataaagc aatggattat
      361 ttagcagttt tatcggatat accactaaga aaaagaagaa aaattatagc aaagttatta
      421 agcaaagtaa accttactaa ttatcaaaat gtgaaagtaa aatctttatc tggaggtatg
      481 aatagaaggc ttgggatagc acaagcatta attcataatc ccagagtttt aatagtagat
      541 gagccgacag caggtcttga cccagaagaa cgtataagat ttagaaattt actatgcgaa
      601 attgcaaatg atagaatcgt tattttatct acacatattg ttggagatat agaagctaca
      661 tgtgaaaacg tagctatatt gaatagtgga aaagtcatat acaatggctc aacagaagca
      721 ttagcaaaac tagctgaagg gaaagtatat agtattgaag tagataaaaa agatattgaa
      781 aatataaaaa gtagatttat agttatagga atgttgactc atggtggaaa ggctatactt
      841 aggattatat cagatgataa accttttgag acagcagtaa attgtaatcc aactattgaa
      901 gatggctata tgcttataat gggaggagat aatatatgaa tctatttata aaagaatgta
      961 aaaatatatt aaagagtatg atatattata tttttattgt agttttagtt tttttctata
     1021 tttctcaact tggaagttca gtttcaaatg atgtaagtaa aaatattcct aatgatggaa
     1081 atccattagt tgctccacaa aaagtagaga atattgagga atattactct gtacacaatc
     1141 aatatccata tggtcaaaaa gaatctatga aaacagaaaa agtcattcca aatgcaacta
     1201 taaacctaat tagagaatat caaaaaaaca catatacaac gtatccaaca ggggtagtta
     1261 agtatataaa attagaccaa aataaaacga agaccataga aaaatatata gaagaaataa
     1321 ctggtaaaag tattagcgaa ataaattcac tttggaaaac tgatgaaagt ataaaaatag
     1381 attattctaa agtatctctt gaaagatttg aagaaataat gcaaagagta gacgacattt
     1441 taggaggagg gtctgcatat gcttttgaca agttacaaag atttggagta gttccagtta
     1501 cctatgatga agctatgaag aattacaact atacaataca aaaagataaa gttagtaatg
     1561 ggtatgcaag aattttttgc gattatatag gtatagtttt aagtatattt ccagtatttg
     1621 tggcagtttt tatgtcactt aaagataagc gttcaagaat gagagagatt atttattcaa
     1681 aacaagtatc ttcatgcaaa atagttttat caagatattt tgcacttgtc tttatgatga
     1741 tattgcctgt attaatttta ggtatgaaag atttacttcc tttgattttc tttgctaaag
     1801 ataaaggtat atctattgat aacttagcat ttataaaata tacattatgg tggatactac
     1861 caactcttat gatagttaca gctgtaggaa tgagtattac tatattaaca gatacaccag
     1921 tagcaattat tgtgcaatta atttggtggc tttacagtat aaattctaca ggactcaaag
     1981 gtgattattc aacaatgggg ctaatgataa gacataatag tgtattaaat ggggatatta
     2041 ttatacaaaa cttcaatcaa attatgatta atagaattgt gataagtttg ggagcattgg
     2101 tgcttgtttt gttagctata ttcttatatg agcaaaaaag aagggggaat cttgatgttt
     2161 gggcaaagtt ttcaaaactg tttagttcta ataaaagaaa acttcaaatt aagcacttta
     2221 actaatttaa tatgttcaat tatattgcta tgtatgattc ctctaataca aggagtagct
     2281 aatttagaca gaatttcaac agctatatgt ttagaaaatt atgttgcaat aatagggata
     2341 gtaatgttgg tacctgtatt ttcgctagag caatcaaaag aaattgatga gatagtatct
     2401 tcaaaagcat tatctcaagt tattgtacaa ttaattagga tactgatgtc aattataggt
     2461 atagtggtat taatcatagg ttttgtaaat gttttaatat atcttggatg taattttcca
     2521 gtagttgagt atattattgg aagtttcgca tcagctatgt ttataggaag tttaggaatg
     2581 tttttctcaa atttatttaa taatacaatc ataggttata tgatatctat aggatattta
     2641 attttaaata tgatgactaa aggcaagtat gttggaaaat tttttataat gtctatgagt
     2701 caaggtagtt ttgatgagaa atattggctg atacttggaa gtgttgtgtt gataattgca
     2761 tctctcttaa taaaaccagt aaaaaggaag attagataat aaaatgagag cttagataaa
     2821 ataaaggtaa tgcaaataaa aagtacattt atgaaatata aatctatttt tatatacaca
     2881 aacctactta caatctcttt atgtatgtag atagatttat atatccgtag tataaaatat
     2941 atatgtatac cgaattttat caaaagctct caaatttata tttcaaagac acttattgct
     3001 atgacctaca catatgtatt ttttcatttt aattgttgta ttaacaatag gactattgtt
     3061 ataaactatt gatacctcat aacaaaaaat tctccatctc ctaaatgcgt tttttgtacc
     3121 ttagtctcaa ctattttaaa tccttgagac tcataacatt ttacagctct catgttccag
     3181 gttcttacat ttaatacaat tggtttagta ctatatttat ttctacattc ttgtaatcct
     3241 aggctaatta tttctttacc aattcccatt ccacaataat tcggtttcaa ccaataccaa
     3301 agaatacaga gcttccttca tctaataagt ttataaaacc tatcaattct ttattgtcat
     3361 ttataaaact tataaaattt tttcttttat cttcttttgc tagtgaaaaa ttcttctttt
     3421 taatttcctc ccatggaggt agattgtata ttgaatattt accttcatat ttccaattag
     3481 taacttcaat agcatgttct tcagtaaatt taactttatt taaattcata tgtcctccta
     3541 ttaaaatatt taaggtaatt aatggtattt taaagtttta gaaaataagt aaaactattt
     3601 atatttatcc ataaaatctt taaaaatttt actaacaatt cttgtaccct gtacttttta
     3661 ttggattcac agaagactat aaactaattt tgaatcacct tctaattcaa aaacatcacg
     3721 atatatataa tttcttagct tgattaaatt ctgttaaatc cgtttcttat agttgtataa
     3781 tcaacatcaa tatctttatg tgtattagtt aatttattgg ttttaggaac ttattattaa
     3841 tatattgtat ttgctccaat aatccaagta gtaggtaaat tataggcaaa ttatcaaatg
     3901 tatatctatc catgc
//
LOCUS       DAJMZY010000186         3686 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.191, whole genome shotgun sequence.
ACCESSION   DAJMZY010000186 DAJMZY010000000
VERSION     DAJMZY010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3686)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3686)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3686
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.191"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            261..620
                     /locus_tag="OE968_003658"
     CDS             261..620
                     /locus_tag="OE968_003658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002583503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCP7220886.1"
                     /translation="MKLRESYTCPLELVHDIIKGKWKTIIIFQLRNGKCSFSELHHSI
                     AGITQKMLLEQLRELKHFGLIDKKTYDGYPLKVEYFLTGQGEKMLSAIKIMQEIGIDY
                     MVEHGMTEILDEKGICY"
     gene            710..1261
                     /locus_tag="OE968_003659"
     CDS             710..1261
                     /locus_tag="OE968_003659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HCP7220887.1"
                     /translation="MKKALLIIDVQNDYFPNGKCQLYKPEIALNTIKDLLKIFRKQNL
                     PIIYIRHESIHGTFFNPNTNGVQIHNDIKPLDTETVIVKHYPNSFYETNLQNKLVEIE
                     VTKLVVCGMMTHMCIDTTIRAAKDYGYEITLISNGCATKELKWNGVNIPADTVQSIFM
                     ASLNQKFANVITSTEFLSNEITR"
     gene            1245..1610
                     /locus_tag="OE968_003660"
     CDS             1245..1610
                     /locus_tag="OE968_003660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009291267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCP7220888.1"
                     /translation="MKLRDEYTCPLELIHDMIKGKWKPIILWRLRLGATSLSKLENDI
                     DGITQKMLLEHLKELIDYGFVDKKTFSGYPLHVEYFLTEDMGNQILEALRIMQHIGIE
                     YLRKNGMENELTEKHVIPD"
     gene            1698..2198
                     /locus_tag="OE968_003661"
     CDS             1698..2198
                     /locus_tag="OE968_003661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015393784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbhB/YbcL family Raf kinase inhibitor-like
                     protein"
                     /protein_id="HCP7220889.1"
                     /translation="MYISSIGISNGIIEKKYGSHGVQFNENDVPTYSIPFKIENAPDK
                     TVSFAFILEDKDAYPVTGFIWVHWLGANLTRSELKENESQTAKDFIQGANSWTSILGN
                     QQTREQTSCYGGMAPPDKAHIYELHVFALDKLLDLKNGFYLNELYQEMEGHILEEAVL
                     KGLYEK"
     gene            2188..2703
                     /locus_tag="OE968_003662"
     CDS             2188..2703
                     /locus_tag="OE968_003662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016285890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HCP7220890.1"
                     /translation="MKSKPVKVGLRTIKTVLSAFLCFLIDSLRASSVPFYAVIASILC
                     IQPDMENSLSVAKNRELSTIIGGILGMLFLLMERIFLPIQPEILRELTLSILLIPIIN
                     LSVLLKQKKGTFLTCVVFLCVTVTHEKDISPIWFAWNRIVDTSLGIGISLAVNSFPFH
                     KFKVGGTMGKY"
     gene            2697..2978
                     /locus_tag="OE968_003663"
     CDS             2697..2978
                     /locus_tag="OE968_003663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HCP7220891.1"
                     /translation="MLIVEFTEKEDAVFQQAVEWLSSKLAYTPASFNQQKKGFDIDPL
                     TRTFTNEEGTSIYLTAKEFDLLYFLSSHKGQVFTKEQIYEKVWGYDNFY"
     gene            3346..3570
                     /locus_tag="OE968_003664"
     CDS             3346..3570
                     /locus_tag="OE968_003664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008393106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220892.1"
                     /translation="MIGIKKRDIKKALKAGAKAGGSSYADVLADIEATIDEVMNSTDP
                     EVQANFKKYFGNKRPTPEEYIYKITKKTRV"
     gene            3592..>3686
                     /locus_tag="OE968_003665"
     CDS             3592..>3686
                     /locus_tag="OE968_003665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006863419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HCP7220893.1"
                     /translation="MKNEMWVLCPICNNKTRTKVREDTELINFPL"
BASE COUNT         1329 a          501 c          721 g         1135 t
ORIGIN      
        1 ttccccatag aataccttat cgcctaaatc attacgagaa agcccagctt tttcacgggc
       61 ttctctgatt gccagcccta gcggtctgaa atcaaaagta tgtgtttctt ttgtttttct
      121 cattttaaat caccatacat gagtttatac ttcatggttc gtatttagaa tgtgttaaaa
      181 gtgcatatat tagggtaata aaatatgttt tgaaatattg agcttaaaca tgtaagatat
      241 ttcacatagg agatgataaa atgaaactta gagaaagcta tacatgtcca ttagaacttg
      301 ttcatgatat tataaaggga aaatggaaaa cgataattat ttttcaactt agaaatggaa
      361 aatgctcttt ttccgaactc catcacagta tagcaggaat tactcaaaaa atgctattgg
      421 aacaactgcg tgaattaaaa cactttggct taattgataa aaaaacatat gatggatatc
      481 ctctaaaagt agaatacttt ttaactggac agggagaaaa gatgctatca gcaattaaga
      541 taatgcaaga aattggtata gattacatgg tagagcatgg tatgacagaa atccttgatg
      601 aaaaaggaat ttgttattaa actctatcat atacacgaaa aagtaagtaa tttacttaga
      661 aactattatc ttatattatt taattagaat taagagagga tatgagagta tgaaaaaagc
      721 attacttatt attgatgtgc agaatgatta ttttcctaat ggaaagtgcc agttgtataa
      781 accagagatt gcgttgaata caataaaaga tttattgaaa atttttagaa agcaaaactt
      841 gccaattatt tacattcgcc atgagtctat ccatggaaca ttttttaatc caaatacaaa
      901 tggtgtacaa atccataatg atattaaacc attagataca gaaacagtta ttgttaaaca
      961 ttatccaaat agtttttatg aaacgaattt gcaaaacaaa ctggtagaga ttgaggtaac
     1021 gaaattggtt gtttgtggaa tgatgacaca tatgtgtatt gacacaacta taagagctgc
     1081 caaagattat ggctatgaga ttacactaat atcaaatggt tgtgcgacca aggaattaaa
     1141 atggaatgga gtcaatatcc cagcagatac agttcaaagc atatttatgg cttctttaaa
     1201 tcagaaattt gctaatgtta ttacaagcac ggagtttttg tcaaatgaaa ttacgagatg
     1261 aatatacatg tcctttggaa ttaattcatg atatgataaa gggaaaatgg aagccaatta
     1321 ttttatggcg cttacgatta ggtgctactt cattatctaa attagagaat gatattgatg
     1381 gaattacaca aaaaatgctt ttggaacatt taaaggaact tatagattat ggatttgttg
     1441 ataaaaaaac attttctggt tatccacttc atgtcgagta ttttttgacg gaagatatgg
     1501 gaaatcaaat actagaagca ttacgaatta tgcaacatat agggattgaa tatttaagga
     1561 aaaatggaat ggaaaatgaa ttaactgaga aacacgtgat tccagactaa tacctacaaa
     1621 aaagtgggta atttacgttt tgcttcctct ttgttaatat atatctgtaa ttaaacgata
     1681 tacaaggagg aaaatttatg tatatttcaa gtataggaat ttctaatgga attattgaaa
     1741 aaaaatatgg tagtcatgga gtgcaattca atgaaaatga tgtgccaacg tattcaattc
     1801 cgttcaaaat tgaaaatgca ccagataaaa cggtttcctt tgcctttata ctggaagata
     1861 aagacgcata tccagtgacg ggttttatat gggtgcattg gttaggagct aatctaacaa
     1921 gaagtgaatt aaaggaaaac gaaagccaga cagcaaagga ctttatacaa ggtgcgaata
     1981 gctggacaag catattgggg aatcagcaaa ccagagaaca gacaagctgt tatggtggaa
     2041 tggcaccacc agataaagca catatttatg agcttcatgt atttgccctt gataaactgc
     2101 ttgatttaaa aaacggattt tatcttaatg aactctatca agaaatggag gggcacatcc
     2161 ttgaagaagc tgtactaaaa gggttgtatg aaaagtaagc ctgttaaagt tggattgcgg
     2221 acaattaaga cggtactttc tgcgttcctt tgttttttga tagatagctt aagagcttca
     2281 agtgttcctt tttatgcagt gattgcgtct atactgtgca tacagccaga tatggaaaac
     2341 agtttgagcg ttgctaaaaa cagggaactt tcaacaatta tcggcggtat actgggaatg
     2401 ctctttttgc ttatggaaag aatttttttg cccattcagc cagaaatact tcgggaattg
     2461 actttatcta ttttattgat tccaatcatc aatctgtctg tactgttgaa acagaaaaaa
     2521 ggaacatttt taacgtgcgt tgtattctta tgcgtaacag taacacatga gaaagatata
     2581 agtcctattt ggttcgcatg gaataggatt gttgacactt cattagggat tggtatttca
     2641 ctggcagtaa actctttccc ctttcataaa tttaaggtag gtggtactat gggaaaatac
     2701 tgattgttga atttactgaa aaagaggacg ctgttttcca acaagcggtg gaatggctgt
     2761 cctctaaact tgcttacacc cctgcttctt ttaatcagca gaaaaaagga tttgatatag
     2821 acccattaac ccgtaccttt accaacgaag agggaacgtc tatatatctg actgctaaag
     2881 aatttgacct actatatttc ctttccagcc acaaaggaca ggtgttcaca aaagaacaga
     2941 tttatgaaaa ggtatgggga tatgacaatt tttattagtc tggcaataat gaagaaaaaa
     3001 gaattttaga aaagtgaggt gtgcttatgg atttatctat tttggtagta gtattgatat
     3061 tgggtgtggg tattccttta agaaataagg caatcaaaaa atacagataa aatatgaaaa
     3121 agaaaggaaa aatgaaaaaa tatgaatatt tagaaattga ttatactgcg aaaggtgttg
     3181 tattcctttg caccgataaa cataaggaag ttataaatag ctatgcagaa aatgggtatc
     3241 gctatgcggg ttcgtgccta cagaaattga cgcaaaaggc tgtatgcgaa agatagattt
     3301 aatttttgaa aaagaagatt aacgtatttt agggagttgg ttcttgtgat aggaattaaa
     3361 aaacgagata ttaaaaaagc attgaaagct ggtgcaaagg ctggtggttc ttcgtatgct
     3421 gatgttttgg ctgatattga agcaacgatt gatgaagtta tgaacagcac cgacccagaa
     3481 gtgcaggcaa atttcaaaaa gtattttgga aataaacgcc ctacaccaga ggaatatatc
     3541 tataaaatca cgaagaaaac acgagtttaa agaattagta agggtggttc tgtgaaaaat
     3601 gaaatgtggg tattatgtcc tatttgcaat aataagacac gaactaaagt gcgagaagat
     3661 acggaattga taaattttcc tttgtt
//
LOCUS       DAJMZY010000187         3539 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.192, whole genome shotgun sequence.
ACCESSION   DAJMZY010000187 DAJMZY010000000
VERSION     DAJMZY010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3539)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3539)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3539
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.192"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            93..1469
                     /locus_tag="OE968_003666"
     CDS             93..1469
                     /locus_tag="OE968_003666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk family potassium uptake protein"
                     /protein_id="HCP7220894.1"
                     /translation="MKTIVRRLILYADGMRPTQIMVSGFAAIIVIGALLLTLPIASQS
                     GESIGLLNALFTATSAVCVTGLVMVDTATYWSLFGQIVIITLIQIGGLGFMTVATMFS
                     LMARKKIQLRERLLIQESLNQADLSGLVRLTRFVLIITITIEGIGALVLSTVFIPQFG
                     LSKGIWYSVFHAISAFCNAGFDLMGSVSGPFTSLNSYVNNFTVSMTVCALIVLGGLGF
                     PVVLDIVRKRRFSKLNVHSKVVLFSTATLIFVGALFIFLIEFNQKATMADLPLKGKVL
                     SAIFQSVTARTAGFNTLDLATLRESSVFVMIILMFIGASPASTGGGIKTTTLAVLIIT
                     VRSFLSGKSDIEAFERRLAPSTIKKSLGIFVISISAVIFGTLIISITQPNFTLVQSAF
                     EVTSALATVGSSLAGTPNLNALGKIIIIIFMFMGRVGSLTLFMAILSGGRRKSQPIRY
                     AEGKIMVG"
     gene            1756..2427
                     /locus_tag="OE968_003667"
     CDS             1756..2427
                     /locus_tag="OE968_003667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HCP7220895.1"
                     /translation="MKQYIVIGCGRFGSSVASTMHLLGHQVMAIDKNEDSVQSISDKV
                     THSLIVDVTDEQALRSLGLGNFDVAVVAIGSDIRASIMATLIAKEMGVELIICKAKDE
                     LQAKVLYKIGADRVVFPERDMGVRVAHNLVSDNILDHIELDPEYSIVEIVTPNSWVGK
                     TLIELELRARYEITVLAIKTGKNINVTPSPDEELTAGSILVIIGQNTSITAITSGNKG
                     IIRRR"
     gene            2616..3413
                     /locus_tag="OE968_003668"
     CDS             2616..3413
                     /locus_tag="OE968_003668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HCP7220896.1"
                     /translation="MITNINSKDNEKLKYTRALLKSKNRNKESKFIIEGYRIVMLALE
                     CMANLDYVFINEEFENKKEHVKLLEDLDKKNTKIYKTTNKNFKELVDTENTQGIIGVV
                     SFKKKKLSESINKKDKFVLILDRIQDPGNMGTIIRTADSAGVDAIIALKGCVDIYNPK
                     VIRSTMGSIFDVNIIDASQDETVDMLKSLDFNIVSSYLNTENFYDKIDYGSKVALVIG
                     NEANGINEELVSKSDILVKIPIYGKAESLNAAISSAILMYEIKKYLI"
BASE COUNT         1338 a          397 c          664 g         1140 t
ORIGIN      
        1 taatagaata ataatttaga ggaaagctct aaaaataaac aaattaaggg tcttaacagt
       61 agtgatttta tgttaaggag gtataaagaa agttgaaaac aatagttaga agacttattc
      121 tctacgcaga tggaatgcgt cctactcaaa taatggtatc tgggtttgct gcgattattg
      181 taatcggagc attgttgtta acactcccga tagcgtcgca gagtggagag agtataggct
      241 tattaaatgc tctatttacg gctacttcag cggtttgtgt tactggtcta gttatggtag
      301 atacagcaac ttattggagt ttatttggac agatagttat aataacattg atacaaattg
      361 gtggtcttgg atttatgacc gtagccacaa tgttttcact tatggcacga aaaaaaatac
      421 aactaagaga aagattatta atacaagagt cattaaatca agctgattta tcgggacttg
      481 taagacttac aagatttgta ttaataataa ccataacaat agagggaata ggtgcactgg
      541 ttttatcaac tgtctttatt ccacaatttg gtttgtctaa agggatatgg tatagtgtat
      601 ttcacgcaat atcagcgttt tgtaatgccg gatttgactt gatgggcagt gtaagtggcc
      661 catttacatc gttaaattct tatgtaaaca actttacagt atcaatgact gtttgcgcac
      721 ttatagtgct tggagggcta ggattccctg ttgtacttga tattgtaaga aaaagaagat
      781 tttcaaaatt aaatgtgcat tctaaggttg tattgttttc aactgctaca cttatttttg
      841 tgggtgcatt atttattttt cttatagaat ttaatcaaaa agctactatg gcggacttgc
      901 ctttaaaggg aaaagtacta tcagcaatat ttcaatcagt aacagcaaga actgctggtt
      961 ttaatacgct tgatttagct actttacgag aaagtagtgt atttgtaatg ataattttga
     1021 tgtttattgg agcatcacct gcatcaactg gtgggggtat aaaaacaaca acactagctg
     1081 ttttaatcat tacagttaga agttttctat caggaaaatc agatatagaa gcttttgaaa
     1141 gaagattagc tccatcaact ataaaaaaat ctcttggtat atttgtaatc agtatatcag
     1201 cagttatttt tggaacattg attatttcaa taactcagcc taattttaca ttagttcaat
     1261 cagcttttga ggttacatca gcacttgcta cagttggttc aagtttagct ggaactccaa
     1321 acttaaatgc tttaggtaag attataataa taatctttat gtttatgggt agagttggtt
     1381 ctcttacttt atttatggct atactttctg gtggtagaag aaagagtcaa ccaatcagat
     1441 atgcagaagg taaaattatg gttggttaag ttaccaagga gtaatataaa tttataatgg
     1501 atttagagta gcactgtaaa tctgttgata aaataaatga gcctagatgt aattatatga
     1561 agaaataaaa tcgactaacg aacaaaatta attaatgaaa taaaaaaaca gggaaataaa
     1621 atacaaataa aaaggtaaat caaaattaaa ttaatctgtg tatataaaat tatatattgt
     1681 gtataagttt tgtatgtgta aacaattaat ttaagagata ttatataaat tgtgtattag
     1741 ggaggaagtt tcgagatgaa gcaatatata gtcattgggt gtgggagatt tggaagttca
     1801 gttgcgtcta ctatgcatct tttaggacat caagtaatgg caatagacaa aaatgaagat
     1861 tcagttcaaa gtatatctga caaggtaacc cattcactta tagtggatgt tactgatgag
     1921 caagcgttaa ggtcattagg tttaggtaac tttgatgtag cagtagttgc aataggttct
     1981 gatataaggg catctataat ggcgactctt atagccaaag aaatgggtgt agagttgata
     2041 atatgtaagg caaaggatga attacaagct aaagtgcttt ataaaattgg cgcagataga
     2101 gttgtatttc cagaaagaga tatgggagta agagttgcac acaatttagt ttcagataat
     2161 atattagacc atattgaact tgacccagag tattcaattg ttgaaatcgt aactccaaat
     2221 agttgggttg gcaagacact tatagagctt gaattaagag ctagatatga gataactgta
     2281 cttgctataa aaacaggtaa aaatataaat gttacacctt ctccagatga ggaacttaca
     2341 gccggaagta tcctagttat aatcggtcaa aatactagta taacagcgat aacatctgga
     2401 aataagggga taattagaag aagataattt actatttaat atatatttaa ttgcaatgaa
     2461 agtagatagt atcatataat tatgaatagt tatatgatac tattttttta atcgaaggta
     2521 gtatttattt gtaagattag ataaagagaa attaaattaa aagtaaggag gctgtgctaa
     2581 tataaaaatt tataagttat tagcatttag ataaaatgat tacaaatata aacagtaagg
     2641 ataatgaaaa gttaaagtat acaagagcac tattaaaatc aaagaatagg aataaagagt
     2701 caaagttcat aatagaggga tacagaatag taatgcttgc acttgaatgt atggcaaacc
     2761 ttgattatgt atttatcaat gaagaatttg aaaataagaa agaacatgta aaactattag
     2821 aagatttgga taaaaaaaac acaaagatat acaagactac taataaaaac tttaaagaat
     2881 tagtggatac agaaaatact caaggaataa taggtgtagt ttcatttaag aaaaaaaaat
     2941 taagtgaaag tataaataaa aaagataaat ttgtattgat tttagacaga atacaagacc
     3001 caggaaatat ggggactata ataaggactg ctgattctgc tggagtagat gccataatag
     3061 cactaaaggg atgtgtcgat atatacaacc caaaagtaat taggtctact atgggttcta
     3121 tttttgatgt gaatataatt gatgcttcac aagatgaaac tgtggacatg cttaaatcat
     3181 tggattttaa tatagtttca agttacttaa atacagaaaa tttttatgac aaaatagatt
     3241 atggctcaaa agtagcattg gtgataggaa acgaagcaaa tggaataaat gaagaacttg
     3301 tatcaaagtc tgatattttg gttaagatac ctatatatgg taaagccgag tcgttaaatg
     3361 ctgcgataag ctctgctata ctgatgtatg aaataaaaaa atacttaatt taatgtattg
     3421 taataaatat aatgtcatgt tataatcttg aattaaatag tagagtatca aaaatagtca
     3481 atatatatta aaaaaataat taaattaatt atatattaga tgtatattat ataaaaaat
//
LOCUS       DAJMZY010000188         3480 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.193, whole genome shotgun sequence.
ACCESSION   DAJMZY010000188 DAJMZY010000000
VERSION     DAJMZY010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3480)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3480)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3480
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.193"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            22..1107
                     /locus_tag="OE968_003669"
     CDS             22..1107
                     /locus_tag="OE968_003669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HCP7220897.1"
                     /translation="MRKYMNKFKLKRSILISLIILIFIFIVYFVSIELKDRSLVNNQY
                     KGKIKSANLSVDYEINQVMKDIDKLGLNTVNVPIIINVESINSDIMSIDNNSKEKAIK
                     LIKKLNKKGISTILEAYPWIENGKLYETDWNPINKKRFFYTWQNAILNELIIDVANPL
                     DVNVLNIGSNFVHLEEYQQNWGEIIDFVQSKFDGFVTYRTNWWYTKKDDLSSKLFYEQ
                     KLNNNFFDKLDFISIAAYFELSNKPVNTVDELISALHSSTVNNRGQNIKQEIYNLYKA
                     HRKPIFFGELGFSNRESASSQPWNHTPSKAVNGEEQARCFEAYKKVFENEDWINGFSV
                     FCVGKIDDEKNFYPSKESIKVIKSWYE"
     gene            1161..2285
                     /gene="wecB"
                     /locus_tag="OE968_003670"
     CDS             1161..2285
                     /gene="wecB"
                     /locus_tag="OE968_003670"
                     /EC_number="5.1.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase
                     (non-hydrolyzing)"
                     /protein_id="HCP7220898.1"
                     /translation="MNDIKVMTVFGTRPEAIKVAPLIKELEKRENIKSIVCVTAQHRE
                     MLDQVIETFNINVDYDLDIMEKGQSLNDITCKILNKLPLILNKENPNIILVHGDTTTT
                     LATSLTAFYNKTLVGHIEAGLRTYDKYSPFPEELNRQLTGIIADMHFAPTNLARKNLI
                     SEGKPNNNIFVTGNTAIDALKMTIKENYNHPIIDEIGNDRMILLTSHRRENLGKPMKN
                     IFRAIKRIVDDFEDVQIVYPIHLNPKIRTIADEIFGKFPEKIHIIEPLDVADFHNFLN
                     KSYMIMTDSGGMQEEAPSLGKPVLVLRDKTERTEGIEAKTLKLVGTNEDRIYNSVSDL
                     LINKDNYVQMSKASNPYGDGNASKYIVDIIIKKFNCKYLN"
     gene            2363..3337
                     /locus_tag="OE968_003671"
     CDS             2363..3337
                     /locus_tag="OE968_003671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HCP7220899.1"
                     /translation="MARKLIKNLGKSKSVKRVKLLFKKIFITVFIVASIVAIFNITKY
                     FEELYKVRDLKSTKIEYYMDVADEAGDGKVQLSWKALLAIDMVIHDEDLSNIKKKDTL
                     DIGEKFIVEDKNDKGEKVYKVKKFNKVLSELKFDSSQKSRARKYMKDLEYTYLGNKQL
                     DSSDEKIKFIKKLEDSAIREYIDYGILPSITIGQAILESGWGNSKLTKQSNNLFGIKA
                     DKAWKGKSVEISTSEHYNEKIVASFRSYNSLQDSVKDHSLFLINNKRYRKHGLFEAKD
                     YISQAQSLENAGYSTAEDKKGNRIYAELLIDVIRSYNLQLIDNKVETK"
BASE COUNT         1459 a          336 c          604 g         1081 t
ORIGIN      
        1 attttaaaag aggtatataa tttgaggaaa tatatgaata aatttaaatt aaaaagaagt
       61 attttaatct cattaataat cttaattttt atatttatag tttactttgt aagtattgag
      121 ttaaaagata ggagtctagt aaataatcaa tataaaggta agattaaatc ggccaattta
      181 tctgtagatt atgaaataaa tcaagttatg aaggatatag ataaattggg attgaataca
      241 gtaaatgtac ctataattat aaatgtagag tccattaatt ctgatattat gtcaatagat
      301 aataatagta aagaaaaggc aattaagtta ataaaaaaat taaataaaaa aggtatttca
      361 acaatattag aggcatatcc atggattgaa aatggaaaat tgtatgagac tgactggaac
      421 cctataaata aaaaaagatt tttttatact tggcaaaatg ccatattaaa tgaacttata
      481 attgatgtag caaatccact ggatgtaaat gttttaaata ttggttctaa ttttgtacat
      541 ttggaagaat atcaacaaaa ttggggtgaa ataatagatt ttgtacaatc caaatttgac
      601 ggttttgtaa cgtacagaac taattggtgg tatacaaaaa aagatgattt aagtagtaag
      661 ttgttttatg aacaaaagct gaacaataat ttttttgata agttagattt tatatctata
      721 gcagcatatt ttgagttaag taataaacct gttaatacag tggatgaatt aatttctgcc
      781 ttacactcat ctactgtaaa caatagagga caaaatataa aacaagaaat atataacctt
      841 tataaagctc atagaaaacc tatatttttt ggagaattag gtttttcaaa tagagaaagt
      901 gcaagttctc agccgtggaa tcatactcct tcaaaagctg taaatggcga agaacaagca
      961 aggtgttttg aggcatataa gaaagttttt gaaaatgaag actggataaa tggtttttct
     1021 gtgttttgtg taggtaaaat agatgacgaa aaaaattttt acccatcaaa agagagtata
     1081 aaagttatta agtcttggta tgaataattt tgaaagtgta gaatttatat agattaaata
     1141 gatgattagg agagacataa atgaatgaca tcaaggttat gactgtattt ggaactagac
     1201 ctgaagctat caaagtagca cctttaataa aggaacttga aaaaagagag aatataaaaa
     1261 gtattgtttg cgttacagct caacatagag aaatgcttga ccaagttata gaaaccttta
     1321 atataaatgt agactatgat ttggatataa tggaaaaagg acaaagcctg aatgatataa
     1381 catgtaagat tttaaataaa cttcccttga ttttaaacaa ggaaaatcca aatataatat
     1441 tggtacatgg agatacaacc acaactctag ctacaagttt gactgcattt tataataaaa
     1501 ctcttgttgg tcatatagaa gctgggctta gaacctatga taaatattct ccttttccag
     1561 aggagttaaa tagacaactt acaggtatta ttgctgatat gcactttgct cctactaatt
     1621 tggctagaaa aaacttgatt tctgaaggaa aacctaataa taatatattt gtaactggta
     1681 atactgctat tgatgcttta aagatgacaa taaaagaaaa ctataatcat cctataattg
     1741 atgagattgg taacgatagg atgattttac taacctctca cagaagagaa aatttgggta
     1801 aacctatgaa aaatatattt agagctataa agcgaatagt agatgacttt gaagatgtac
     1861 agatagtata tcccatacat ttaaatccta aaatacgaac tatagctgat gagatatttg
     1921 gaaaatttcc tgaaaaaatt catattatag agcctttaga tgtagctgat tttcataact
     1981 ttttaaataa atcttatatg ataatgactg atagtggagg aatgcaggaa gaagctccat
     2041 cattaggtaa gccagtcctt gtgttgcgtg ataaaacaga aagaacagaa ggaattgaag
     2101 caaagacact taaattagta ggtactaatg aagatagaat atataattca gtgagcgatt
     2161 tattaataaa taaagataac tatgttcaga tgagtaaagc atctaatcca tatggagatg
     2221 gaaatgcaag caaatatata gtggatataa taattaaaaa atttaattgc aaatatttaa
     2281 attagataag acctaaaaca ttaactaatt gatataagat ttatgataat attaaggaat
     2341 acaattttta agggggagta atatggctag aaaattaata aaaaatttgg gtaaaagtaa
     2401 aagtgtaaag agagtgaaac ttttatttaa gaagattttt attactgtat tcatagtagc
     2461 aagtatagtt gctattttta atataacgaa atattttgag gaattataca aagtaaggga
     2521 tttaaaaagt actaaaattg aatactatat ggatgtggct gatgaagcag gagatggaaa
     2581 ggtccaatta agttggaagg ccttacttgc tatagacatg gtaatacatg atgaagattt
     2641 aagtaatata aaaaagaaag acacattgga tataggggaa aagtttatag tagaagataa
     2701 aaatgataaa ggcgaaaagg tgtataaggt aaaaaagttt aataaggtat taagcgaatt
     2761 gaaatttgac tcttctcaaa aaagtagagc aagaaaatac atgaaagatt tagaatacac
     2821 ataccttgga aataaacaat tagatagtag tgatgaaaaa attaaattta taaagaagtt
     2881 agaagactca gctataagag aatatattga ttatggaata ttgccctcta taacaattgg
     2941 acaagctata ttagaatctg gttggggaaa ttctaaactt acaaaacaga gtaataattt
     3001 atttggtata aaagcagata aagcatggaa aggaaaaagt gtagaaattt caacttcaga
     3061 gcattataat gaaaaaattg tagctagttt taggtcgtat aattcattac aagattctgt
     3121 caaagaccac agtttatttt taattaataa taaaagatat agaaaacatg gattgtttga
     3181 ggcaaaagat tatattagtc aagctcaatc attagaaaat gcaggatata gtacagcaga
     3241 agataaaaaa ggaaatcgta tatatgcaga gctattaata gatgttatta ggagttataa
     3301 tttgcaattg atagataata aagttgagac aaaataattg ttaactttat atgaggagat
     3361 aacaagataa gattcttttc tacaaaaaga atagaaaaat tgtaaaaaaa actaaaaaaa
     3421 tgtattgact tgttatttaa aaggtgatat tattattact gtactcgaaa gagaacaaaa
//
LOCUS       DAJMZY010000189         3466 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.194, whole genome shotgun sequence.
ACCESSION   DAJMZY010000189 DAJMZY010000000
VERSION     DAJMZY010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3466)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3466)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3466
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.194"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            complement(<1..781)
                     /locus_tag="OE968_003672"
     CDS             complement(<1..781)
                     /locus_tag="OE968_003672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HCP7220900.1"
                     /translation="MISNKMQTLVANSSVIRAMFEEGKKLSDIYGEENVFDFSIGNPS
                     VEPPETIKAVINDILNEESPNLVHGYMNNSGYEDVRDAIAEHINKKDGLNLTRENLIM
                     TCGAAGGLNIILKTLLNPGDEVIAFAPYFGEYKNYTENYDGKLIEVPTNIETFEPDLD
                     ALKNAITPKTRALIINTPNNPTGVIYSEELLKNLGELLDSKQKEFNTSIYLISDEPYR
                     EIIYDGAKVPCVLKYYRNSFIGYSYSKSLSLPGERIGYIVAN"
     gene            1087..1533
                     /locus_tag="OE968_003673"
     CDS             1087..1533
                     /locus_tag="OE968_003673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HCP7220901.1"
                     /translation="MDFKNLQYESLSYIICNLQKNFKLYCEKCLKPYKLTNGLYFYLI
                     YINKNRNCSLNDVSTEFEVDKAHTTRTISRLEQDGYIEKIQNPNDSRAFQLRVTDKGE
                     EVLGDIKNIFSKWDNHIKKEFSDTEYKELVKNLHVVKDIKTAVEEE"
     gene            1535..2629
                     /locus_tag="OE968_003674"
     CDS             1535..2629
                     /locus_tag="OE968_003674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH:flavin oxidoreductase"
                     /protein_id="HCP7220902.1"
                     /translation="MYCNLLKPIKIGNLELKNRVSFAPTSMGLKLEEKIKKFSDIAKS
                     GVALITLGDVSIRPSFHKVAISLSDEDGVMKYKKIVDEIHNSGAKVSAQLFCSDYDVN
                     LIKDTMNMGITSHDEIKKIMNDGVKDYITNMPKEEIKNIINLFKVTALNAKKAGFDMI
                     QIHGDRLVGSFSSSIFNNRNDEYGRTCDNRSRFASEIISSIRDEVKDIPIDYKFAIRQ
                     ENPHYGNAGVLLSEVEYFVKKFESLGVNSFHVTLANHSKLEDTIPTNNHPYFKEEGCF
                     LYLADEVKKHTNLPVCGVGKLSSPDFIESIISNNRVDMVSMSRQLLADRNWLQKVKDG
                     RVDEIKKCCYCNKKCADALQTRSQFGCILD"
     gene            2717..3247
                     /locus_tag="OE968_003675"
     CDS             2717..3247
                     /locus_tag="OE968_003675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HCP7220903.1"
                     /translation="MKSLVLYSSLTGNTKKIAYTIYDEIQEEKDIKDVNELVDYSIDY
                     ENYDIVFLGYWVDKGICDKNSKQVLENIHNKKIALFGTMGASKKGSYGASIIEKIESI
                     IPKDNEILGSFICQGKIAEGLKAKYKEMLKLSPDNEHIRQQLNNHEESQSHPDEQEIY
                     EASMFAKNMMIKASIV"
BASE COUNT         1377 a          384 c          539 g         1166 t
ORIGIN      
        1 cattagcaac aatatatcct atacgttcac caggtagaga taatgattta ctataagagt
       61 atcctataaa tgaatttcta tagtatttta gtacacaagg aactttggca ccatcataaa
      121 ttatttctct atatggctca tcagaaatta ggtatatgct tgtattaaat tctttttgtt
      181 ttgaatccaa taattctcca agatttttta ataattcttc agaatatatg acaccagtag
      241 gattatttgg agtgtttatt attaaagctc ttgtttttgg agtaatagca ttttttagag
      301 catctaaatc tggctcaaaa gtctctatat ttgtaggaac ttctattaat tttccatcat
      361 agttttctgt ataattttta tactcaccaa aatacggtgc aaaagcaata acttcatcac
      421 caggatttaa aagagttttt aaaataatat ttagaccacc agcagcacca caagtcataa
      481 ttaaattttc tcttgtaaga tttaatccat cttttttatt tatgtgttca gcaatagcat
      541 ctcttacatc ctcatatcct gagttgttca tatatccatg aactaaattt ggagattctt
      601 catttaaaat atcatttata actgctttaa tagtctctgg aggttcaaca cttggatttc
      661 ctatactaaa atcaaaaaca ttttcctcac cataaatatc agaaagtttc tttccttctt
      721 caaacatagc tcttataaca gaactatttg caactaaagt ttgcatttta ttagatatca
      781 tatgtaacac tcctttttat agatttatat tgcttatgta tatattacca tatttttact
      841 gaatttagac aattttcgaa aaattacttg tttgaaaata taaactttta tataaaatat
      901 atttatgtac agtacatatt aaaaattcca atttctaatt ttatcatgat tattttatat
      961 aatagttttt taaagaatta ataaaacata gatttagaga ataaaatatt cttgactata
     1021 ttaattgttt aatataatat agttgatata gtcaaacata ttataattat agaagggaaa
     1081 tttaagatgg attttaaaaa tttacagtat gaaagtttgt catatattat ttgtaacttg
     1141 caaaaaaact ttaaacttta ttgtgaaaaa tgtttaaaac catataaact tacgaatggt
     1201 ctatatttct atttaattta tattaataaa aataggaatt gttctttgaa tgatgtttct
     1261 acagaatttg aagttgataa agctcataca acaagaacta tatctaggtt agaacaagat
     1321 ggatacatag aaaaaatcca aaaccctaat gatagtagag cttttcagtt gagagtaaca
     1381 gataagggtg aggaagtatt aggggatata aaaaacatat tttcaaagtg ggataatcac
     1441 ataaaaaaag agttctcgga tacagaatat aaggaactgg taaagaattt acatgtggta
     1501 aaggatataa aaacagctgt ggaggaagaa taggatgtat tgtaatttat taaaaccaat
     1561 taaaattgga aatttggaat taaaaaatag agtatctttt gcacctacaa gcatgggtct
     1621 taaattggaa gaaaaaatta aaaagttttc tgatattgct aagtcaggag tagctctgat
     1681 tactctagga gatgtatcta ttagacctag ttttcataag gtagctataa gcctatcgga
     1741 tgaagatgga gtcatgaaat acaagaaaat tgtagatgaa atacacaatt ctggtgcaaa
     1801 ggtatcagca caactatttt gttcagatta tgatgttaat ttaattaaag atactatgaa
     1861 tatgggaatt acttcacatg atgagataaa aaaaataatg aatgacggag taaaagatta
     1921 cataacaaat atgcccaaag aagaaattaa aaatattata aatttattta aagtaacagc
     1981 attgaatgca aaaaaagcag gttttgacat gattcaaatt catggtgata ggcttgtagg
     2041 aagtttttca tcaagtatat ttaataatag aaatgatgaa tatggtagaa cgtgtgataa
     2101 tagaagtaga tttgcaagcg aaataattag tagtatccga gatgaagtta aggacattcc
     2161 aatagactat aaatttgcaa taagacaaga aaatcctcat tatggaaatg caggagtttt
     2221 actttcggaa gttgagtatt ttgttaaaaa atttgaatcc ctaggtgtaa acagttttca
     2281 tgtaacactt gcaaatcatt caaaattaga agatactata ccaaccaata atcatcctta
     2341 ctttaaagaa gaaggctgtt ttttatattt agctgatgaa gtaaagaaac acacaaatct
     2401 tccagtatgt ggggttggaa aattgtctag cccagatttt atagaaagta ttatttcaaa
     2461 taatagagta gatatggttt ctatgtcaag acaattacta gcagatagga attggttaca
     2521 gaaagtaaaa gatggaagag tagatgagat taaaaagtgc tgttattgta ataagaagtg
     2581 tgcagatgct ttacaaacac gctctcagtt tggatgtata ctagattaga atatccttat
     2641 aaaaataaat aatttgttaa ggttaatata tttttggtga tttagataag tatttagata
     2701 aagaggagga gacatcatga aaagtttagt tttatattca agtttaactg gaaatactaa
     2761 aaagattgct tatactatat atgatgaaat tcaagaagaa aaagacatta aagatgtaaa
     2821 tgaattagtt gattatagta ttgactatga aaattatgat atagtattct taggctattg
     2881 ggtggacaag ggaatttgtg ataaaaattc aaaacaagtg cttgaaaata ttcacaataa
     2941 aaagatagca ctatttggaa caatgggagc aagtaaaaaa ggaagttatg gagctagtat
     3001 aatagaaaag atagaatcaa ttatcccaaa agataatgaa atattaggtt cattcatatg
     3061 tcaaggtaag atagcagaag gattgaaagc aaaatataaa gagatgttaa aactttctcc
     3121 tgacaacgaa catattcgcc aacaattaaa taaccatgag gaatctcaaa gtcatccaga
     3181 tgaacaagaa atatatgaag ccagtatgtt tgcaaaaaat atgatgatta aagctagtat
     3241 tgtgtagtag ttaaacaata agttcatata agatatagaa taaataattt agtaaaaaag
     3301 tatagcaaat aatttgctat gcttttttta tgaaatcaaa aaaataataa aaatacttga
     3361 ctgtaaacct tgtttataca ttattttata gaaaataaga tagttttaaa tataaaaaaa
     3421 gatatattat tgaaaggaga tattattgta tgaaaactta taaaag
//
LOCUS       DAJMZY010000190         3373 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.195, whole genome shotgun sequence.
ACCESSION   DAJMZY010000190 DAJMZY010000000
VERSION     DAJMZY010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3373)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3373)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3373
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.195"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            complement(93..458)
                     /locus_tag="OE968_003676"
                     /pseudo
     CDS             complement(93..458)
                     /locus_tag="OE968_003676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423610.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
     gene            complement(479..1558)
                     /locus_tag="OE968_003677"
     CDS             complement(479..1558)
                     /locus_tag="OE968_003677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF917 domain-containing protein"
                     /protein_id="HCP7220904.1"
                     /translation="MRFLTEESVDKIAVGAAVLGTGGGGDPYVGKLVAKQAIKKYGPV
                     KVISLDELDDDALVVPVSGMGSPVITIEKLLSEVELTTPLEIMEKLLNRKVDVIIPIE
                     IGGINSLMPIAVAAKKGLPILDADSMGRAFPEAQMVTFYLEGYEASPAVMSDEKGNSA
                     ILYPVDGIWSERLARTLTVEMGGSSSISDYNLSGAQVKKAAIGNTLTIAETIGGFLLE
                     NKSDSKGAVENILKELRGYKLFEGKVIDIKRELKGGFTRGHAFFAGINEYDGEYSILF
                     QNENLIAKKGDTPLCITPDLIAVLDLETGFPITTERIKYGSRVMVVAFPCNEKWRTEK
                     GIETVGPGYFGYDVEYKTVEELQGK"
     gene            complement(1612..2901)
                     /locus_tag="OE968_003678"
     CDS             complement(1612..2901)
                     /locus_tag="OE968_003678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytosine permease"
                     /protein_id="HCP7220905.1"
                     /translation="MEEEKINYALEQIPENQKRGWVAMFSVLVAIGVDLSSVILGAEL
                     AQSMPMKQAILSVIVGSFFSAILYTTCSLVGSSTSLSTSMITKYVFGEAGAKIFSLVI
                     GVSLLGWFGVQVGFFAQNAQIIIKDIFNLDVSMQILSLIGGLLMMSTAIYGYKAMEKL
                     SVYSVPFLLVLMMLTIFLAFRANGISVDDNMKSTMTFAGGVSLSMSIIIVGAIVSPDI
                     SRWAKSRRDCALSSFLGIQFGNAFMIIVSIVLVKCMGTSDIMRIFITLGIAIPGIIVL
                     TLAQWTTNTSNVYSASLSIALVLKKAPEKVLTIVLGIIATLLAVFGIYEGFIGFLNLL
                     GIVIAPVGGVYTAEYYIVKQELKGFDKGVLYKPIVKRSIVSWIIGILITYLSTYGFIT
                     LTTIAPLDGFIAGFVVQSIIGKVLCSTKNKQEIDKAV"
     misc_binding    complement(3064..3275)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
BASE COUNT         1110 a          678 c          371 g         1214 t
ORIGIN      
        1 tatcctatct ctacatatag gtttccctat atgctgacta ttttagctac taactcatga
       61 ctaaagtcac gagtgtgcgt agctattttt taatcaaact catatccacc agataccaat
      121 attgaatcta attctatttt ttctcttaag tcttctggcc aatctataaa tggaagaatg
      181 gcagtagtgg ctggctttcc tattcttatc atagccacat tattaagtct ttttctttct
      241 acaatagcat ttgtacaatg agttgtacca agcatagcat attttattaa tgaatggtca
      301 atcttacttt catctataac tttttttaag gcattgtaaa caccagtttc aacatctttt
      361 gtagttgcca ccttaactga atgaattact tttaattccc catccagtat acaagcatct
      421 gtatttgttc ctccaacgtc aattcctaca cgatacatca aaatttcctc ctaaactttt
      481 attttccttg taattcttct actgttttat attccacatc atatccaaag tatccaggtc
      541 caactgtctc aattcctttt tctgttctcc atttttcatt acaaggaaaa gctactacca
      601 taacacgaga gccatatttt attctctctg tagttattgg aaatccagtt tctaaatcta
      661 atactgctat taaatctggt gtaatacaaa gtggtgtatc accttttttg gcaattaaat
      721 tctcattttg gaataatata gaatactctc catcatactc attaatccca gcaaaaaagg
      781 catgtcctct agtaaatcca cctttcaact ctctcttaat atcaattact tttccttcaa
      841 ataacttgta tccacgcaat tcttttagta tattctcaac agcacctttt gaatcagatt
      901 tattttcaag taaaaaccct cctatagttt cagctattgt aagagtatta cctatagcag
      961 cttttttaac ttgagctcca cttaaattat agtcactaat agaagaactt cctcccattt
     1021 ctacagttaa agttctagct aatctttctg accaaattcc atccacagga taaaggatgg
     1081 cagaattacc tttttcatca gacattacgg caggagatgc ctcatatcct tcaagataaa
     1141 aagttaccat ttgagcttca gggaaagctc tacccataga atctgcatct aagataggaa
     1201 gtcctttttt agcagcaact gctataggca taagtgagtt tatccctcct atttctatag
     1261 gaattataac atccactttt ctatttaata atttctccat tatttctaaa ggggtagtta
     1321 actcaacttc tgaaagtaat ttttctattg taattacagg agaacccata ccagatactg
     1381 gaactaccaa agcatcatca tcaagttcat ctaaacttat tacttttaca ggaccatact
     1441 ttttaatggc ttgttttgca accaatttac ctacatatgg gtcacctcca cctccagttc
     1501 caagcactgc tgcaccaact gctattttat ctacactttc ttctgttaaa aatctcatgt
     1561 tactttctcc tcatatttct aatttatttt atactttata aacaaatttc tttatactgc
     1621 tttgtctatt tcttgcttat tttttgttga acaaagcact tttccaataa tagattgtac
     1681 tacaaaccct gctataaaac catctaaagg tgctatagta gtaagagtta taaatccata
     1741 tgttgaaagg taagttatta atataccaat tatccaagac actattgaac gtttaactat
     1801 tggtttatat aatactcctt tatcaaagcc tttaagttct tgctttacta tgtaatattc
     1861 tgctgtatat acaccaccaa caggtgcaat tacaattcca agtaaattta aaaatcctat
     1921 aaaaccttca tatattccaa atacagccaa taatgttgct ataataccaa ggactatagt
     1981 taatactttc tcaggagcct tcttaagtac aagagctata cttaatgatg ctgaatatac
     2041 attacttgta tttgtagtcc attgtgctaa tgtaagtact attatacctg gtatagcaat
     2101 tcctaatgta ataaaaattc tcataatatc tgaagttccc atacatttta ctaatactat
     2161 cgaaactatt atcataaaag catttccaaa ttgtattccc aaaaagcttg aaagagcaca
     2221 gtctcttcta cttttagccc aacgacttat atcaggagat acaattgcac caactattat
     2281 tatactcatt gacagagaaa ctccacctgc aaatgtcata gtagatttca tattatcatc
     2341 aactgaaatt ccatttgctc taaaagctaa gaatatagtt agcatcataa gaactaataa
     2401 aaatggtact gaatacacac tcaacttctc cattgcctta tatccataaa ttgcagtact
     2461 catcatcaag agaccaccta ttaggcttaa aatctgcata cttacatcta aattaaatat
     2521 atcttttatt attatctgtg cattttgagc aaagaaacct acttgaactc caaaccaacc
     2581 taatagagaa acccctataa ctagagaaaa tatttttgct ccagcttctc caaatacata
     2641 ctttgttatc atagatgtag ataaacttgt agatgagcca accaaagagc atgtagtata
     2701 caaaattgca gaaaaaaatg aaccaacaat tactgacaat attgcttgtt tcattggcat
     2761 actctgtgcc aactcagcgc ctaaaataac agatgataaa tccacaccta ttgctactaa
     2821 aactgaaaac atagctaccc aaccacgttt ttgattctct ggaatctgtt ccagagcata
     2881 gttaattttt tcttcttcca ttttcatccc tccatttaaa tcgtaaaact actgacctta
     2941 gcatatttta caattttcta atttataaat ttattaacta tcatattttt ataattttca
     3001 tttaatatat agttttaaat tttctgaaat aagtttataa taaaaaacgc ctcttggaaa
     3061 aatccaagag acgaatataa atccgtgtta ccactcttat tagtaaaaat taattttact
     3121 cactcatttt cttaaggcga attaaaccac tattctaaca taattacaat agtattctcc
     3181 aaagtccttt tcacataaat tccaatatta gttctcagcc aaatctaact ctctgtaaaa
     3241 ttcctttatg ctactttctt cttctacgaa tatataatat tgatttgtag ttaatttatg
     3301 atttatatca taatatatat gcaatatttt gtcaacttaa aaagtcaatt acttgcattt
     3361 tttagtttta tat
//
LOCUS       DAJMZY010000191         3323 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.196, whole genome shotgun sequence.
ACCESSION   DAJMZY010000191 DAJMZY010000000
VERSION     DAJMZY010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3323)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3323)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3323
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.196"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            complement(79..255)
                     /locus_tag="OE968_003679"
     CDS             complement(79..255)
                     /locus_tag="OE968_003679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220906.1"
                     /translation="MFRDKMDKCTHMLTAYIGSSYDYCDFIDTQLDDFILEYGEKVVE
                     SCLHQVMVLVSKYN"
     regulatory      complement(309..398)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            complement(578..778)
                     /locus_tag="OE968_003680"
     CDS             complement(578..778)
                     /locus_tag="OE968_003680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCP7220907.1"
                     /translation="MPKFTCNLKKYRQLKELTQEQLAEKVGVRRETIMRLEAGKYNPS
                     LKLAIDISKIVDTPIDELFIFD"
     gene            complement(780..1130)
                     /locus_tag="OE968_003681"
     CDS             complement(780..1130)
                     /locus_tag="OE968_003681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3796 domain-containing protein"
                     /protein_id="HCP7220908.1"
                     /translation="MIQKKFFMGFCGFLGFLSLRYFSSGNVADLTYIGFFAFFSNFII
                     SKINGDKADERYVQDEKAAMAFTGQLAIIELFILWCITIVSRNIELMCVLLSITYAIT
                     LNVYAIKLYILEEK"
     gene            1292..1481
                     /locus_tag="OE968_003682"
                     /pseudo
     CDS             1292..1481
                     /locus_tag="OE968_003682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890498.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1958..2128)
                     /locus_tag="OE968_003683"
     CDS             complement(1958..2128)
                     /locus_tag="OE968_003683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220909.1"
                     /translation="MHVYQPKTSEYLLNTYAKSYLSSIVFLFDYITKNESGYAFFIID
                     FPFLSLDIFYKF"
     gene            complement(2517..3011)
                     /locus_tag="OE968_003684"
     CDS             complement(2517..3011)
                     /locus_tag="OE968_003684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HCP7220910.1"
                     /translation="MKNKKGFTLVELLVVIAIIGILAIVALPALFKNIEKAKIAKLEA
                     DISAIKSASLSYYADESKYTDGGMISWVKKDGKIIINGGFKDDPLADKIENLGMPYNG
                     SYLLMSSPGHEKYLELSILPEGEISKSGLDKLKSDYGSSIDIMNEQNKIDIVIKFLND
                     KSNT"
BASE COUNT         1304 a          436 c          371 g         1212 t
ORIGIN      
        1 atttaaacat tttatattac caatatatta atgtaaatgt agataaaact aaaaagggtt
       61 ttctagaaaa aaatctgtct aattatactt acttaccaat accatcactt gatgcaagca
      121 agattccaca actttttctc cgtactctaa tataaaatca tctaactgtg tatctataaa
      181 atcacaataa tcatatgaac taccaatata agcagttaac atatgtgtac atttatccat
      241 tttatctcta aacataatgt atttatcccc ctaaaaaact ttcatgaaaa acaaaaagaa
      301 aatatctttt tggcaactgg ctgacataac ttattttata agcgttagtc cctatagctt
      361 tgcgtcacta aatttctcta gttttgccga tttagtttta ttctacagat taataataca
      421 atagaattag ttattattca acatatctag ctgaaaaatt aataaattta tatatgaacg
      481 ttaaattatc tgaaaaaata aaaagcccct ctgtcaggag tgacttaaaa attgaattta
      541 agtttgtatt taaaacacat ttttaataat gcaaaaacta atcaaaaata aacaattcat
      601 caataggtgt atctactatt tttgatatat ctattgctaa tttcaaagaa ggattatact
      661 ttcctgcttc taaacgcata atggtttctc ttctaactcc tactttttct gctaattgtt
      721 cttgagttaa ttcttttaat tgtctatatt tttttaggtt acaagtgaat ttaggcatat
      781 tatttttcct ctaaaatata aagttttata gcataaacat ttaaagtgat tgcatatgta
      841 attgatagta aaacacacat taattctata ttcctagaca ctatagtaat acaccataaa
      901 atgaataatt ctataatagc aagctgtcct gtaaatgcca tagctgcttt ttcatcttgt
      961 acataccttt catctgcttt atcaccattt atttttgata taataaagtt tgagaaaaaa
     1021 gcaaaaaatc caatatatgt aaggtcagca acattgccag atgaaaaata tctaagactt
     1081 aaaaatccaa ggaaaccaca aaaacccata aaaaattttt tctgaatcat tttttatcct
     1141 ccttagtaat tttaaaagag atatatttat atctttatga tacaaatata tctcttttat
     1201 attcttttgt caatagaaaa tcagtattat acaatatttg tactgcacca taattgttag
     1261 agcaaaaatc tactgcttga gatgtttatg tatgactaaa tatgatttta atttcaaatt
     1321 aaaagtagct aaattttatt tgaatagaga aggaagagat attttaatag taaaacaata
     1381 tggagtttat aaccattctc aagttgaaag atgggttaat atattaggag agtgtgcact
     1441 aaaaataaaa aaaattttct atactatatg gttcaagtta gatgttataa actatatgat
     1501 gataactaaa tatagtgtac aataaatcgc taagtatttt ggaataaaca atagcacagt
     1561 tatagcaaca tgaaaataaa aatttttaca tagtggtgtt gatgcctttt ctaaaatgaa
     1621 aggaagacca taatgaataa aaacaaaaac actaaagaaa aaataaatta acaagagaac
     1681 aagaattaga atatgaaaat aaatttttaa aagatgagct tgagttttta aaaaagatgt
     1741 gtgcctcagg gaagccacat taaaaaacag tggtatcatt attaatcaaa agaaagttag
     1801 atgtattatc aaaaaattag aacttaaatg catagcattt tttcataaat cacataaata
     1861 taactcctat aaatgtataa ttggaaaagt aaaaaataat aaaacaaata gaagatttaa
     1921 aatatcaata gcatatcaga aaataacaaa tgatatgcta gaatttataa aatatatcta
     1981 atgataaaaa tggaaaatca attataaaaa aggcatatcc cgattcattt tttgttatat
     2041 agtcaaataa gaatactata gatgaaagat acgattttgc atatgtatta agtaagtatt
     2101 ctgatgtttt tggttgatac acatgcaata aagaagttgt gtttgcagat aaattagcaa
     2161 aactatagta taagttgcaa caataaagaa aatgaaaatt atcatactaa agcataaggc
     2221 atgttacaat tttattagat aggacattaa catacattaa agtacttttt attataaaga
     2281 gtacttattt ttttgaaatt cattaatgta taaactatca agaatattac tcaacataat
     2341 ttaaaaacaa cttgaatagg tatttttaaa ttatgtgata taataaaaaa tagaagtgta
     2401 tgccaataca cttctgtaat tataactaag cattctattc ttgaggagtg cttttttcat
     2461 ttctccaaac aagattgttt atttcatcag caattattaa ataaaattta ttgtatttaa
     2521 gtattcgatt tatcatttaa aaattttatt acaatatcta ttttgttttg ctcgttcatt
     2581 atgtctattg aacttccata atcacttttt aatttatcta gaccactttt gcttatttct
     2641 ccttctggaa gtatacttaa ttctagatat ttttcatgac caggagatga cattaataga
     2701 tatgaaccat tataaggcat acctaaattt tctattttat ctgctaatgg gtcatcttta
     2761 aagccaccat ttattattat ttttccatct ttctttaccc atgatatcat tcctccatca
     2821 gtatattttg attcatctgc atagtagcta agagacgcac tttttattgc acttatatca
     2881 gcttcaagtt tagctatctt tgctttttct atatttttaa ataatgctgg aagtgctact
     2941 attgccaata ttcctattat agcaattact actaataatt ccactagagt aaatcctttt
     3001 ttatttttca tttatttccc ctccatataa aattaataat atataaattt ttattttgtt
     3061 gatttctact ttctatattt taccatatat agacaaaaaa atcactttct atgacaaata
     3121 tactattatt ttacaattta tggaaatgat ttaaaatgac atttcttgtt agaaaagata
     3181 taagaaatgg attaaaataa agaaaactac agtcatatca atgtcaataa tattatttaa
     3241 aagcagatga aaataaaaag aggactcaga aaataatgtc tatttaatta tacttactta
     3301 ccaataccat aacttgatat aaa
//
LOCUS       DAJMZY010000192         3316 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.197, whole genome shotgun sequence.
ACCESSION   DAJMZY010000192 DAJMZY010000000
VERSION     DAJMZY010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3316)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3316)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3316
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.197"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            complement(258..434)
                     /locus_tag="OE968_003685"
     CDS             complement(258..434)
                     /locus_tag="OE968_003685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220911.1"
                     /translation="MFRDKMDRCTHMLTAYIGSSYDYCDFIDTQLDDFILEYGENVVE
                     SCLHQVMVLVSKYN"
     regulatory      complement(488..584)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            1381..1782
                     /locus_tag="OE968_003686"
     CDS             1381..1782
                     /locus_tag="OE968_003686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNHCP domain-containing protein"
                     /protein_id="HCP7220912.1"
                     /translation="MNYKNRKRAYYQENSCMDNFICKNCGCLVVPEGAGTQHRNHCPH
                     CLHSLHVDIIPGDRAADCDANMEPIGVWVRKNGEWAIIHRCTRCGHLSSNRIAADDNS
                     VKLMSIALKPLAQPPFPLERIIEKLEKEETE"
     gene            1779..2846
                     /gene="rsgA"
                     /locus_tag="OE968_003687"
     CDS             1779..2846
                     /gene="rsgA"
                     /locus_tag="OE968_003687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HCP7220913.1"
                     /translation="MNGMKQINLQDYGLNRNFITQSMEYHDLYLARIISQEKNFYQAV
                     CVNGVLFAEVSGKLRFEATIQSDFPTVGDFVMLDRCNNKNGNAIIHHVLHRKSLFVRK
                     AAGKVNEEQVVAANIDIVFLCMSLNKDFNIHRLERYLSLTWESGAIPVVVLTKSDLCD
                     NVHRKLQVVNSIALGVDVVVTSSIEPDGYKQISKYIKPGCTVALLGSSGVGKSSLINC
                     LMGGEFLNTKEIRIDDDKGRHATTRRELFLISGGGIVIDTPGMRELGMWDVSEGLDKS
                     FADIEAYFGKCHFRNCTHTSEPGCAIWEAIAHQELSPKRWESYRRLKTEAVFADNKSE
                     YLAKKEKKFKNISKINKKIRR"
BASE COUNT         1191 a          410 c          544 g         1171 t
ORIGIN      
        1 tttgttaatc taatccttca aactaaaaaa tcatttatat ttacagaatt tcattttaag
       61 agatgtttat tttcacatag ataagagaat ttaagttctc atatttatta tttgatacaa
      121 atttacatct ttattatatg tattttaaat aaaaaataaa attatgaata ctagaaatct
      181 atcttaatta gctttctaac ataaggctat ttaaagtaga taaaactaaa aagggttctc
      241 tagaaaacca aatctattta attatactta cttactaata ccatcacttg atgcaaacaa
      301 gattctacca cattttctcc gtactctagt ataaaatcat ctagttgtgt atctataaaa
      361 tcacaataat catatgaact accaatataa gcagtcaaca tatgtgtaca tctatccatt
      421 ttatctctaa acatatatat tattatcccc ctaaaaaact ttcataaaaa caaaaagaat
      481 atctcttttt ggcaactggc tgacataact catagtttat tttataagcg ttagtcccta
      541 tagctttgcg tcactaaatt tctctagttt tgccgattta gttttattct acaattacaa
      601 taatacaata gaattgctta ttattcaata tacttatttg aaaattaaat aaatttacaa
      661 atatgaacgt tattttatat caaaaaaaat agactatgca tgtagaatat atggaaaaac
      721 ttgattgtag gttttgtatg aaaagacagt tgttattaat ttaagtgaga taaattgagc
      781 aacaggcata aaatgagaaa acaaataata gcagttaatt tttattatta atactaggtg
      841 aacattaaat ttcaaaatac cactagattt tatagaataa gaaaatgaga caaacataaa
      901 tatatgaata tattaaatta tacttgaaca tacttatatt ttatgataaa atttcaataa
      961 taattattag tgaaggagtg tcttgcctga tgtcagagtt atatataatg gtaaccaaca
     1021 aataaatagt tggagacgca tatgggttct gtttaatcag aatttttaag tgtatttttg
     1081 atacatttga ttgttgtgtc ttactctgcc tttatagata actaacatta gacaacaaat
     1141 aataatatta catattactt tgttaaattg tggtgtagtg ggctttaatc tgctacactt
     1201 ttattaattt tacacagtat tattttgaat ataattatgt tgaaatagaa gatactaaat
     1261 tttctagtcc acaggggttt tctgtttttg tgtaggtaaa tatgtatacc acataaaaag
     1321 gcagatataa atacctgtgg actttttttg tagaaaatac acgatacgga ggaaataaaa
     1381 atgaattata aaaatagaaa acgagcttat tatcaggaaa attcctgtat ggataacttt
     1441 atttgcaaaa attgtggttg ccttgtagtt cctgaaggag ctggtacaca acatagaaat
     1501 cattgtccac attgtttaca tagtcttcat gtagatatca ttcctggtga ccgtgctgca
     1561 gattgtgatg ctaatatgga acctattgga gtgtgggtga gaaaaaatgg tgagtgggca
     1621 attattcatc gttgtacacg ctgtggacat cttagttcta atcgtattgc agctgatgat
     1681 aattcagtga aattaatgtc aattgcatta aaaccactgg cacagccccc tttcccacta
     1741 gaaagaatca ttgaaaagtt ggaaaaggag gaaacagaat gaatggtatg aaacaaatca
     1801 atttacaaga ctatggtcta aatagaaatt ttattactca aagtatggaa tatcatgatt
     1861 tataccttgc tcggattatc tcgcaggaaa agaactttta tcaagctgta tgtgtaaatg
     1921 gtgtactgtt tgcagaggtt tcaggaaagc tgcgttttga ggctactata caatctgatt
     1981 ttcccacagt tggtgatttc gttatgttgg atcgttgcaa taataaaaat ggtaatgcta
     2041 ttattcatca tgtgcttcat agaaaaagct tgtttgtgcg taaggctgct ggaaaggtaa
     2101 atgaggagca ggtggttgca gctaatattg acattgtttt tttgtgcatg tcactgaata
     2161 aggattttaa cattcataga ttggagaggt atctgtcttt aacatgggaa agtggagcta
     2221 tcccagtagt agtacttact aaatcagact tatgtgacaa tgtgcatcgt aaattacaag
     2281 tagttaattc tatagccttg ggtgtagatg tagttgttac ctcatctata gagccagatg
     2341 gttataaaca gatttctaag tatattaaac caggctgtac tgttgcctta cttggttctt
     2401 caggagttgg aaaatcttca ttaattaatt gtctgatggg tggagaattt ttaaatacaa
     2461 aggaaattcg catagatgat gataaaggaa gacatgccac gactagacga gagctatttt
     2521 taatttcagg tggtggtatt gttattgaca caccaggtat gagagagttg ggaatgtggg
     2581 atgtttcaga aggtttagat aaaagttttg cagatataga agcttatttc ggaaaatgtc
     2641 attttcgtaa ttgtactcac acctcagaac caggctgtgc tatctgggaa gctattgctc
     2701 atcaagaact ttcgcctaaa agatgggaat cctatcgtag gcttaaaact gaagcagtat
     2761 ttgcagacaa taaaagcgaa tacttagcaa aaaaagaaaa gaaatttaaa aatatctcaa
     2821 aaataaataa gaagattaga agataagtgt agtttttttg ttcattctat gagtctatat
     2881 actattaata tattaaattt gccatcaatt tgttacttta atgtgatttt gatggcaaat
     2941 ttggtttgtg gtattattta aagcaattta ttaatttttt taataaagtt tgatttttta
     3001 tatgatgata tatacatgtg ataatgtata catatttgtt acgataggct cctttataaa
     3061 gaggtcttat gtaagataag aaaaggcata tttatactaa tacataatag agtatatgct
     3121 tatgtatgat agagatgttt cttaagagca aaactgcaat attgctaatt tataaagtaa
     3181 aaatatatga attataaaat acaaataata tatttataaa aattattgtt ttaatttata
     3241 ataaaaattt tttgttgaaa ataatgctcg aacctataaa actattaact aatatttgta
     3301 aatgtatact tttgat
//
LOCUS       DAJMZY010000193         3315 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.198, whole genome shotgun sequence.
ACCESSION   DAJMZY010000193 DAJMZY010000000
VERSION     DAJMZY010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3315)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3315)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3315
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.198"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            complement(85..954)
                     /locus_tag="OE968_003688"
     CDS             complement(85..954)
                     /locus_tag="OE968_003688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HCP7220914.1"
                     /translation="MVIIKAIELYKKLDLEFNIKNINDDWSFMNFENDFITPEFRKKY
                     IGLVLDNAQNINKVYTTTFPDKEIIKQVIDKDEKDILIFSHHAMGYIASDEGFPFHDI
                     PLSYMEEMKNRRISFYVLHSPLDNYSDYSTSVSFAKAMGLEIVKPFCKYDDKIEVGVI
                     CKTSLKSIEEIKELIKKSVGHDVKLYDYGDSVLKDGLVAIAAGGGSYPFVAREVAELG
                     INLYITGFTKPLKHFEPVLEFHQIAKDNLINVIGATHYSTEKFACMGMVDYFKNLGLE
                     SEFLQGKYYLEDL"
     gene            complement(1258..1728)
                     /locus_tag="OE968_003689"
     CDS             complement(1258..1728)
                     /locus_tag="OE968_003689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase/bleomycin resistance/dioxygenase
                     family protein"
                     /protein_id="HCP7220915.1"
                     /translation="MKYQVSLLAVKDIEVSKKFYKELFEQEIELDLGKNVTFKGGFAI
                     QEDFAWLTGINPDTIIQKSNNMELYFEVDDFDEFIEKLNYYKDVEFVHKPLKHEWQQR
                     VVRIYDPDKHIIEIGESMEVIARRYLSEGYSVEETSKIIQHPIKFVKQCENSKE"
     gene            complement(2462..2851)
                     /locus_tag="OE968_003690"
     CDS             complement(2462..2851)
                     /locus_tag="OE968_003690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HCP7220916.1"
                     /translation="MTIKKLPQSELKIMKFIWKSDSKVTSRDIVLGMEQKYQWKQTTT
                     LTLLSRLVVKRFLNSQKIDKYTHYEVLIKEKEYIGVETRDFFRNIHDSSIKSLLLSLH
                     ENINLSKDDILLIEEWIKNLKEEEKDV"
BASE COUNT         1085 a          536 c          255 g         1439 t
ORIGIN      
        1 aaaacactgg ataaataggt aaaaaaataa acagttagta aaataaattt ttactaactg
       61 tttattttta ttgtttaata tgtcctataa atcctctaag taatactttc cttgcaaaaa
      121 ttctgattct aaacctagat ttttaaaata atcgaccatg cccatacacg caaatttttc
      181 tgtagaataa tgagtagcac ctataacatt aattaaatta tcttttgcta tttgatggaa
      241 ctctaatact ggttcaaaat gttttaaagg cttagtaaac ccagtaatat atagatttat
      301 accaagttca gcaacttctc ttgctacaaa tggataactt cctccccctg ctgcaatagc
      361 aactaaacca tcttttaata cagaatctcc ataatcatac aatttcacat catgaccaac
      421 agatttttta attaattcct taatctcttc tattgatttt agtgatgttt tacatataac
      481 tcctacttca attttatcgt catatttaca aaatggtttg actatttcta aacccatagc
      541 ttttgcaaaa ctaacagaag ttgaatagtc actatagttg tctagtggag aatgtaatac
      601 ataaaaagaa attctacgat ttttcatctc ttccatataa gatagtggta tgtcgtgaaa
      661 tggaaaacct tcatctgatg ctatgtatcc cattgcatga tgtgaaaaaa ttaaaatatc
      721 tttttcatct ttatctataa cttgcttaat tatttcttta tcaggaaaag tagttgtgta
      781 tactttatta atattttgag cattatctaa tactaatcct atgtattttt ttctaaattc
      841 tggagtaata aaatcatttt caaaattcat aaaactccaa tcatcattaa tatttttaat
      901 attaaattct aaatctaatt ttttataaag ttcaattgcc ttaataataa ccactccttt
      961 ataataatat tgaattacta catattaata tagaaatttc cgataataaa ctttatacgt
     1021 ttaagtattc ctacttcaaa ttaaaaatat tataaatatt caaatttatt aatatatttt
     1081 aatattatat ttattttttc tttattaata ttccccttat ttttatttat tttttcttta
     1141 ttaatatttt ctttatttta atttaattta tgacatttgt caaatactag tcctatatat
     1201 tatcttgaat tagttctatt acaattaatt tctactaaat aattataatt taaacaatca
     1261 ttccttacta ttttcacact gctttacaaa tttaattgga tgttgaatta ttttagaagt
     1321 ttcttctaca gagtatccct cagataaata tcttctagct ataacttcca tagactctcc
     1381 tatctcaata atatgcttat ccgggtcata aatacgcact actctttgtt gccattcatg
     1441 ttttagtggc ttatggacaa actctacatc tttataataa ttgagttttt caataaattc
     1501 gtcaaaatca tcaacctcaa aataaagttc catattattt gatttttgta taattgtatc
     1561 tggattaatc cctgtaagcc atgcgaagtc ttcttgtata gcaaatcctc ctttaaatgt
     1621 tacattttta cctaagtcca attcaatttc ttgctcaaat aattctttgt aaaatttttt
     1681 tgatacttca atatccttca ctgctaataa tgaaacctga tatttcataa attttcctcc
     1741 taatttttta tttctatttt ttcagtatct tctattaaca tttttttctc tatctcttca
     1801 gtacctttta ttaatccttt atttttactt ttttagtatc ttctattaac acttttgttt
     1861 ctacctcttc agtatcttat atcaatcttt tattttttca atatcttcta ttaacacttt
     1921 tatctctatc tattcagtac tttctatcaa tcttttgttt ttattttttc aatatcttct
     1981 attaatactt ttgtttctac ctcttcagta tcttatatca atcttttatt ttttcaatat
     2041 cttctgttaa cacttttatc tctatctctt taatatctta tattaatcct ttatttttat
     2101 tttttcaata tcatcattaa ttcctattta ttttatcatc ttaaatacga aaacactgtg
     2161 tcatatttgc aaaatatata ttatcatcta tattaaagct tcacaattta tatttaaaaa
     2221 ttctctttaa ttacactacc tctatttaaa aagctacctt aattatactt ataagtaaag
     2281 gtagcttttt aaatttaatt aaatagaata tccactatta atttttattt aatttattta
     2341 gattcacatt atagtatcat aatccactta taatcatttg tcatattact taagtagact
     2401 aatatattac ataaatacac ttacatacac tttatattga tgctataaga aatacgtttg
     2461 cttatacgtc tttctcctct tcttttagat tttttatcca ctcttcaata agtaagatat
     2521 catctttgct caaattaata ttttcatgta atgacaacaa taaacttttt atagaagaat
     2581 catgaatatt tctaaaaaaa tctcttgtct caactcctat gtattccttt tctttaatta
     2641 aaacttcata atgcgtatat ttatctatct tttgagaatt tagaaatctt tttactacta
     2701 atctagataa aagagtcaaa gttgtcgttt gtttccattg atatttttgc tccattccta
     2761 aaacaatatc tctagatgtt actttggaat ctgatttcca tataaatttc attatcttta
     2821 attctgattg tggcaacttt tttatagtca tgataaaacc ttgctactca gaatatagac
     2881 aagcaatatc cataataaaa tttttcgatt aaatacatct tatacggatt tatataagct
     2941 cagacttata agatattttt caatcttaat cctaaattta gctatttgta cacggtaaat
     3001 atatataaat aatgtcaaaa ttctcttgta ttatattgct taattttatg aaatattttg
     3061 tactcagcta tctattttgg atacttgtcc agtagctctc ctttctttta aactctttga
     3121 ttttaaatat ttgtatttca gtaaatccta cttcctaaat tttttattta ctacaactta
     3181 ttactgaact tcctacttcc taaacttttt atttactaca acttattact gaacttctca
     3241 cttactaaat ttcttactta ctataaatta taactaaact tctcacttac taaatttctt
     3301 acttactata aatta
//
LOCUS       DAJMZY010000194         3313 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.199, whole genome shotgun sequence.
ACCESSION   DAJMZY010000194 DAJMZY010000000
VERSION     DAJMZY010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3313)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3313)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3313
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.199"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            <1..849
                     /locus_tag="OE968_003691"
     CDS             <1..849
                     /locus_tag="OE968_003691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HCP7220917.1"
                     /translation="ITYFIERGNSFIQEFLYDEYGKMTDIQEGHFRINNKEQGWGKVP
                     FIPFKNNEKCVSDLTFYKSLIDIYDNNISTLADNLDEIQEVIYVLKEYPGTSLQEFID
                     NIRYYKSIKVDGGGGVDKLEINIPVEAKKELLDRLEKNIIIFGQGVNPESQNTGDKSG
                     VALKFLYSLLDLKCSKTEKKFKKAIRELLWFVCEYLKISGSKSYDYKTVQITFNHSMI
                     INEAEKIDMAAKSTGIVSDETIVSNHPWVEDVNDELERLKKQEDTQKEYDDLIPNNQD
                     GVIDET"
     gene            839..2332
                     /locus_tag="OE968_003692"
     CDS             839..2332
                     /locus_tag="OE968_003692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HCP7220918.1"
                     /translation="MKHKDYWRKRFEQLEEAQNNKSVKYYLELEKQYKLAINSIEKDI
                     LAWYNRFAKNEGISLLEAKKLLNTRELEEFKWSVEEYIKYGKENAINQKWMKELENAS
                     ARVHITRLEALKLQIQQQVEVLYGNELDGIDKLMRDIYTSGYYHTAFNVQQGVNVGWS
                     LMSLDTNRINKIISKPWAIDGLNFSERIWGKYRPTLVNELHTKLTQSIIRGENPKNLV
                     NDFAKRFNVSKSQAKNLIMTESAFFASASRKDCFSDLEVEKYEIIATLDLRTSNICRE
                     LDGKIFDMKDYQVGITAPPFHCRCRTTTAPWFEDEEGYRAARGEDGKTYYVPSSMKYN
                     EWYEKYVKNNSKQTGAKYTKGDIEWNIRREEEAELYYDNIRNRKDDISKISKNTNWSE
                     KSIGQIKNHIFYNTHIMRDGTRRMLDSDYSMSVAWQRLINGTYEDIDILLLKHEYLES
                     IFEKKYNISNLEAHRMTEKKHDWYKELIKQKGEFEEDDCLNELIRKE"
     gene            2298..2540
                     /locus_tag="OE968_003693"
     CDS             2298..2540
                     /locus_tag="OE968_003693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220919.1"
                     /translation="MIVLMNLLEKNNEYVIYSYGYEENKLDGRIKIYLDDFYNYEIIK
                     ESKDEHISKSATLKAISKLIKAAKNNDLKKEMSYQC"
     gene            2611..2805
                     /locus_tag="OE968_003694"
     CDS             2611..2805
                     /locus_tag="OE968_003694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015981492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220920.1"
                     /translation="MYILTQVIAVVCVVQIFINCIANVNVGILCNKLKEKNEANIDKV
                     SDEILKRVGEELNESLDKSL"
     gene            2850..>3313
                     /locus_tag="OE968_003695"
     CDS             2850..>3313
                     /locus_tag="OE968_003695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage scaffolding protein"
                     /protein_id="HCP7220921.1"
                     /translation="MDWLKELLEGIKIENNKIDVVSLQKSIEKKIKETTITQEDYTNL
                     ETQLNTANETIKKFEGGMTKEDVENLKTTYETDKKTLEETYKKEIEEKDFNYWLGDAF
                     KSVKCRDEIALKAHLDIEALRNSKDRQKAFEEQINPLKQDKDYLFNATLEGE"
BASE COUNT         1432 a          311 c          597 g          973 t
ORIGIN      
        1 ataacttact ttattgaaag aggtaatagt tttattcaag aatttttata tgatgaatat
       61 ggaaaaatga ctgatataca agaaggtcat tttagaataa ataacaaaga acagggatgg
      121 ggtaaagttc catttatacc ttttaaaaat aatgaaaagt gtgtctcaga tttaactttc
      181 tataaatcat taatagatat atatgacaat aatatttcta cactagcaga taacttagat
      241 gaaatacaag aggttattta tgtattaaaa gaatatccag gaacaagtct acaagagttt
      301 atagataata taagatacta taaatcaatt aaagtagatg gtggaggtgg agttgataaa
      361 ctagagataa atataccagt tgaagctaaa aaggagcttc ttgatagatt ggaaaagaat
      421 ataattatct ttggtcaagg agttaatcca gaatctcaaa acacaggtga caaatcgggt
      481 gtagcactta aatttttata ttcactactt gacttaaaat gttctaagac tgaaaagaag
      541 tttaaaaaag caattagaga gcttttatgg tttgtgtgtg agtatttaaa gataagtggt
      601 agtaagagct atgattataa aacagttcaa attactttta atcactctat gataataaat
      661 gaagctgaaa agatagatat ggcagctaaa tcaactggaa ttgtatcaga tgaaactatt
      721 gtttctaacc atccttgggt cgaggatgtt aatgacgaac ttgagagact taaaaaacag
      781 gaagatactc aaaaagagta tgatgattta attcctaata atcaagatgg tgttatagat
      841 gaaacataaa gattattgga gaaagagatt tgaacaatta gaagaagctc aaaataacaa
      901 aagtgtaaaa tattatcttg aattagaaaa gcaatataaa ctagctataa atagtataga
      961 aaaagatata ttagcatggt acaacagatt tgccaaaaat gaaggaatat ctttattaga
     1021 agctaagaaa ctactaaata caagagaact agaagagttt aaatggagtg ttgaagaata
     1081 tattaaatat ggtaaagaaa atgctataaa tcaaaagtgg atgaaagagt tagaaaatgc
     1141 tagtgcaaga gttcatataa caaggcttga agctttaaag ttacaaatac agcaacaagt
     1201 agaagtttta tatggaaatg aacttgatgg tattgataaa ctaatgagag atatttatac
     1261 aagtggatac tatcatacag cttttaatgt tcaacaagga gtaaacgttg gttggagttt
     1321 aatgagtctt gatactaata gaataaataa aattatctct aaaccatggg caatagatgg
     1381 attaaacttt agtgaaagaa tttggggtaa gtatagacct actttagtaa atgaactaca
     1441 tactaagcta actcaatcaa ttattagagg tgaaaatcca aaaaatttag taaatgactt
     1501 tgctaagaga tttaatgtat ctaaatcaca agctaagaat ttgataatga ctgaatcagc
     1561 tttctttgca tcagcaagta gaaaagattg ttttagtgat ttagaagtag agaaatatga
     1621 gattattgct acattagatt taagaacttc aaatatatgc agagagttag atggaaaaat
     1681 atttgatatg aaagattatc aagttggaat aacagctcca ccatttcatt gtcgttgtag
     1741 gacaacaaca gctccttggt tcgaggatga agaaggctat agagcagcaa gaggagaaga
     1801 tggaaaaaca tattatgtac catctagtat gaagtataat gagtggtatg agaagtatgt
     1861 taaaaataat agtaaacaaa ctggtgcaaa atatactaaa ggtgatatcg agtggaatat
     1921 aagaagagaa gaagaagcag aactatatta cgataatatt agaaatagaa aagatgatat
     1981 ttccaaaata tcaaagaata caaattggtc agaaaaaagt ataggtcaaa ttaaaaatca
     2041 tattttctac aatactcata taatgagaga tggaactaga cgtatgttgg attctgacta
     2101 tagtatgtca gttgcttggc aaagacttat aaatggtaca tacgaagata ttgatattct
     2161 cttattaaaa catgaatacc ttgaaagtat atttgagaaa aagtataata taagtaactt
     2221 agaagcccat agaatgactg agaaaaagca tgattggtat aaagaattaa ttaaacagaa
     2281 aggagagttt gaagaagatg attgtcttaa tgaacttatt agaaaagaat aatgaatatg
     2341 ttatatatag ttatggatat gaagaaaata agcttgatgg aagaataaaa atatatttag
     2401 atgattttta taattatgaa ataataaaag agtcaaaaga tgaacatata agtaaatcag
     2461 caacgttaaa agctatttct aaacttataa aagctgctaa aaataacgat ttgaaaaaag
     2521 aaatgagtta tcaatgttag aagcacttac tgaacaataa attagtaggt gcttttatta
     2581 tgtaaaagtt taaaaaagta ggtgatttta atgtatatat taactcaagt tatagctgta
     2641 gtttgtgtag tacaaatctt tattaattgt attgctaatg tcaatgtagg tattctttgc
     2701 aataaattaa aagaaaaaaa tgaagctaat atagataaag tttctgatga aattctaaag
     2761 agagtaggag aagaattaaa tgaatcacta gacaaaagtc tttaaagact ttttttattg
     2821 tgtaaaaaat gaaaggagat atttaaaaga tggattggtt aaaagaattg ctagaaggaa
     2881 taaaaataga aaataacaaa attgatgtag tttctcttca aaaatctata gaaaagaaaa
     2941 taaaagagac tacaattact caagaagatt atacaaatct tgaaacacag cttaatacag
     3001 ctaatgaaac tattaaaaag tttgaaggag gtatgacaaa agaagatgta gagaatctaa
     3061 aaacaactta tgaaactgat aagaaaactt tggaagaaac ttacaaaaaa gaaattgaag
     3121 aaaaagattt taattactgg ttaggtgatg cttttaaatc tgttaaatgt agagatgaaa
     3181 tagcattaaa agctcattta gatatagaag cactaagaaa tagtaaagac agacaaaaag
     3241 cttttgaaga gcaaataaat cctttgaaac aggataaaga ttatttgttt aatgcaacac
     3301 tagaaggtga aga
//
LOCUS       DAJMZY010000195         3299 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.200, whole genome shotgun sequence.
ACCESSION   DAJMZY010000195 DAJMZY010000000
VERSION     DAJMZY010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3299)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3299)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3299
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.200"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            244..1611
                     /locus_tag="OE968_003696"
     CDS             244..1611
                     /locus_tag="OE968_003696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase"
                     /protein_id="HCP7220922.1"
                     /translation="MGLKEFDFIEESIDMLRTMSPTLETISDEIEEYFENILDEKNQE
                     YINVTSRIKSESSLREKIIRNRYLKKYGEASNLIHNVSDLIGLRIECRFIEDENKIYR
                     LLRRYFNKTDDKINYYNKENKNIKLKLSERQPNKQKNGFEIYKIDGVFAYLDREVKFE
                     LQIKSLVNVFWSEIEHKIIYKNNTYLLADKFIKDMMDSIKNNLTMIDNQLLSIYKNFH
                     SGKSFNMKVSKKEIEKLFAKLVYDAFSEKMNKSIGFVVDFKKPCETILNYSFNKQDIS
                     DEVLGNFMLDEFARLNEIVNKDIDFNEQIEFEREPTFDDKFCKDLGNHFRSRLNTEFP
                     WNLFFRILFEIEPYNNTKDFENFVEFIKENVLLEENREQLLCQFEEDSKLIIEDIYDC
                     IFNSISEIDSVEILYNYNLEKINFTSSEIINCICREYECYGEYLEEKEKLMNTFKEKI
                     IQIFE"
     gene            1636..2244
                     /locus_tag="OE968_003697"
     CDS             1636..2244
                     /locus_tag="OE968_003697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor guanylyltransferase"
                     /protein_id="HCP7220923.1"
                     /translation="MRHFSNIYELSKIILEEAICIEKTGVILAGGRNSRMGRDKAFLE
                     LHDKLFIEIAIEAFKNFDELIIISNNEELYSKYDIKVYNDIVKDVGPIGGIYTALEYA
                     KYDIVTIACDMPYLNNQIVERIANKMNDKSVISVTNGKLQPLCSGYKKSIINKVSLCI
                     RENDLKLRSFIDKIDKSYIYFDEEDLFLNVNTVDEYEKLTKV"
     gene            2292..2663
                     /locus_tag="OE968_003698"
     CDS             2292..2663
                     /locus_tag="OE968_003698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HCP7220924.1"
                     /translation="MNLLKCDSWAVILNNSDKESKAYKILDELKRNMYKVVAIDEEKK
                     PIEGIDVYECLKDVPHNIDVVAIIDKQSKMDVILEEVELLDIQNMWFEKGSFSEMMIK
                     KTKDLKLNIEYNLSLYDELTR"
     gene            2842..3180
                     /locus_tag="OE968_003699"
     CDS             2842..3180
                     /locus_tag="OE968_003699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HCP7220925.1"
                     /translation="MLIVTTEKVEGKKISKVLGLVRGSTIRAKHVGKDIGASFKNLVG
                     GELTGYNEMLTEARQIAIGRMVEDAEAKGANAVIAFRLSSASVMQGAAEMLAYGTAVV
                     LEDDNSILEK"
BASE COUNT         1406 a          248 c          573 g         1072 t
ORIGIN      
        1 ttttcttact cattccttaa aattactcat ttagtttaat aactctcatt tcatatgtaa
       61 agttggtaaa aaaattaaaa ttaaaagtaa aaaactaaat aaattaatgt taatttgaaa
      121 tatatatgaa ggtttttgga gaatacttac ttatgatagg aaaaaatgtt aaaataatag
      181 tgtaatcaaa tataaaggac tgaaataatt aacagttatt aaatattagg agtgtaaaaa
      241 tttatgggat taaaagaatt tgattttatt gaagagtcta ttgatatgtt gaggacaatg
      301 tcaccaacat tagaaactat atcagatgaa atagaagagt attttgaaaa tatcttggat
      361 gaaaagaatc aagaatatat aaatgtaacc tctagaataa aatcagaatc aagtttaaga
      421 gaaaagataa ttagaaatag atatttaaaa aaatatggag aagcaagtaa tcttattcat
      481 aatgtttctg acttaatagg cctaagaatt gagtgtagat ttattgagga tgaaaacaaa
      541 atatatagac ttttgagaag atattttaat aaaacagatg acaaaataaa ctattataat
      601 aaagagaata agaatattaa attaaaacta tctgagagac aacccaataa gcaaaaaaat
      661 ggatttgaaa tatataaaat agatggagtt tttgcgtatt tagatagaga agtaaaattt
      721 gaacttcaaa ttaaatctct tgtaaatgtg ttttggagtg aaatagaaca taaaataatt
      781 tataaaaaca atacatattt acttgctgat aaatttataa aggatatgat ggactctata
      841 aagaataatc ttactatgat agataatcag cttttaagta tttataaaaa ctttcattca
      901 gggaagtctt ttaatatgaa agtaagtaaa aaagaaattg aaaaattatt tgcgaaacta
      961 gtctatgacg ctttttctga aaagatgaat aaaagtatag gttttgttgt agattttaaa
     1021 aaaccatgtg agactatatt gaactattct tttaataaac aagatataag tgatgaagtt
     1081 ttaggtaatt ttatgcttga tgagtttgca agattaaatg aaattgtaaa caaggatata
     1141 gattttaatg agcaaataga atttgaaaga gaaccaacat ttgatgataa gttttgtaaa
     1201 gacctaggaa atcattttag aagtagatta aacacagaat ttccatggaa cctatttttt
     1261 agaatattat ttgaaataga gccatataac aataccaaag actttgaaaa ctttgtagag
     1321 tttataaaag aaaatgtgct actagaagaa aatagggagc aattattatg ccaatttgaa
     1381 gaagatagca aacttataat tgaagatata tatgattgta tatttaatag tataagtgag
     1441 attgatagtg ttgaaatttt atataactat aatcttgaaa aaataaactt tacatcaagt
     1501 gaaatcataa attgtatatg tagagaatat gagtgttatg gtgaatactt agaagaaaaa
     1561 gaaaagctta tgaatacatt taaagaaaag attattcaaa tctttgagta ataggtcaat
     1621 gctgaagtgg cgctaatgcg ccatttttca aatatatatg aattaagtaa aattattttg
     1681 gaggaggcga tttgtataga gaaaacaggt gtaattttgg cagggggaag aaattctaga
     1741 atgggtagag ataaagcctt tttagagtta catgataagc tttttattga aattgcaata
     1801 gaagcattta aaaactttga tgagttgata ataatatcta ataatgaaga attatattct
     1861 aaatacgata ttaaagttta taatgatata gtaaaagatg ttggtccaat tggaggaata
     1921 tatactgctc ttgaatatgc aaagtatgat atagttacaa ttgcatgtga tatgccatat
     1981 ctaaataatc aaatagtcga aagaatagct aataaaatga atgataaaag tgtgatttca
     2041 gtgacaaatg gaaagttaca accattgtgt tctggatata aaaagagtat aataaataaa
     2101 gtatctttat gtataaggga aaatgattta aagctcagaa gctttataga taaaatagat
     2161 aaaagttata tatactttga tgaagaagat ttatttttaa atgtaaacac tgttgatgag
     2221 tatgaaaaat taactaaagt ttaattagct atggttgtaa aatagagtag gatttatatg
     2281 gaggagagtt tatgaattta cttaaatgcg attcttgggc agtaatatta aataatagcg
     2341 ataaagaaag taaagcatat aaaatattag atgaacttaa aaggaatatg tacaaagttg
     2401 ttgctataga tgaagagaaa aaacctattg aaggaataga tgtgtatgaa tgtttaaaag
     2461 atgttccaca caatattgat gttgtagcta ttattgataa acaatctaag atggatgtga
     2521 ttttagaaga agtagagctt ttggatatac aaaatatgtg gtttgaaaaa ggaagcttta
     2581 gtgaaatgat gattaaaaag actaaagatt taaaattaaa tatagaatat aatttaagtt
     2641 tatatgatga gttgactaga taaaattata tatcttaata ataaaaatat aattagttaa
     2701 taaaacatat tattttatag tatagattgg ttaataaaag tacagattgg ttaatgaaac
     2761 attaaattac aatatttgtt aaaaaaattg tgagttacat gatataatgt attaaatagg
     2821 atactaagga gttgatatat tatgttaata gtaactacag aaaaagtaga aggtaaaaag
     2881 atatcaaagg ttttaggatt agtgagagga agtacaataa gagcaaaaca tgttggaaaa
     2941 gatataggag caagttttaa gaatcttgtt ggaggagaac ttactggata taatgaaatg
     3001 ctcactgaag caagacaaat tgccataggt agaatggttg aagatgcaga agctaaaggt
     3061 gcaaacgcag taatagcatt tagactgtct tcagcttcag ttatgcaagg ggcagcagaa
     3121 atgcttgctt atggaacagc agttgtttta gaagatgata atagtattct tgaaaaataa
     3181 aatataaata gttaaaaaga ggcatctttt aaaaatttta tggatgcctt tttttatttg
     3241 aaaaaactaa tttgagaaga aattttaact attatgacaa taaaattagg gtgatatta
//
LOCUS       DAJMZY010000196         3209 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.201, whole genome shotgun sequence.
ACCESSION   DAJMZY010000196 DAJMZY010000000
VERSION     DAJMZY010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3209)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3209)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3209
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.201"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            25..756
                     /locus_tag="OE968_003700"
     CDS             25..756
                     /locus_tag="OE968_003700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCP7220926.1"
                     /translation="MIRKKVYILISIAICDDESYMLNHLKENIELYMKQKNLLYNIEL
                     FNKVEDLLCNHEKFNIVFLDIQMEEINGMQAARKLRSYGNECFIIFVTVLNEFVFDAF
                     EVDAINYLIKPLSNEKLYKTLDKIVTKLDDNESNYITIQKGYSYWKLKLADILYCEVI
                     KRKIYVHLKKETVDYYETIENLERSLPTNFFRCHRSYIINLQYVYGYENGNAVMESGD
                     RIPVSRLRQQIFSKVMLEFMKNRRI"
     gene            758..2116
                     /locus_tag="OE968_003701"
     CDS             758..2116
                     /locus_tag="OE968_003701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HCP7220927.1"
                     /translation="MINLFSSDLFLKYSFLFSFIVYRILMVIVQYYFLISFTNVNSKF
                     WCFILYSIISIFLIIINTYFNLYNLFSSQILFFLMTFLFVKYIIKQSTVLSIVSTLLV
                     YLIEQLVYGFTAPLNYLIFTSDINTDIYKFDINMGLSSLITIIIAGFIYWYSSKKFNI
                     KVMNFDKYIAILMIPLLLIILFMQSFEYSSNINIDTSLGIVKLLLNTSITEEIQAFLF
                     SIIGTICVFFSLFTFKKLIQALEDDKERAIMNQQIHAQKNYIEEAKSRLSQTISFRHD
                     FNNHLAIVNGLLKKDQILKAQDYLNKLEKVTSDLSFSCNTQNIVIDALFNNKLSIAKQ
                     LGIEVDCEVIIPQSTNMNDFDLCIVFANAIDNAIKACRVVDKQNRYLKLSTKLEGGFF
                     MIEIKNSYNPINNYTSGSGIGLLNIKEIAKKYQGAISIDKTSDYFQINVLLVISLHCA
                     SI"
     gene            2155..2640
                     /locus_tag="OE968_003702"
     CDS             2155..2640
                     /locus_tag="OE968_003702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220928.1"
                     /translation="MYLNRESLIYRNEEVTKMKVGNINGQAPITNGLDSCQSEVQGLE
                     QKKKSLQDEIEKVRSDKSIDGETAKLKIEALKKEMEEIENKIQELKGNKAKKTNKEEN
                     NVSEVNNNLLERKKEPSNNENVKQLYDVFERSNVDEQWDNTYRVLQDDKNLKVKFNRP
                     I"
     gene            complement(2903..3139)
                     /locus_tag="OE968_003703"
     CDS             complement(2903..3139)
                     /locus_tag="OE968_003703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220929.1"
                     /translation="MLLTHIYFNGQFKQTIELYKQAFNATVKTLIEDSCYLLIVHNEI
                     VIHNKFLILNDFGNKNGVSISEGYQPTDKIQTAS"
BASE COUNT         1266 a          323 c          454 g         1166 t
ORIGIN      
        1 taactttata taataattag aataatgata agaaagaagg tgtatatatt gatttcaatt
       61 gccatttgtg atgatgaatc ctatatgcta aatcatttaa aggaaaatat agaattatac
      121 atgaagcaga agaatttatt atataatata gagcttttta ataaagtaga agatttacta
      181 tgcaatcatg aaaagtttaa tattgtattt ttagatatac agatggaaga gattaacgga
      241 atgcaggcag ctagaaaatt aaggtcatat ggtaatgagt gctttataat tttcgttaca
      301 gttttaaatg aatttgtatt tgatgctttt gaagtagatg ctataaatta tctgataaaa
      361 cctctatcta atgagaaact atataaaact ttggataaaa tagttacaaa acttgatgat
      421 aatgaaagta attatatcac aatacaaaaa ggttattcat attggaaatt aaaacttgct
      481 gatattttat attgtgaagt tataaaaaga aagatttatg ttcatttaaa gaaagagact
      541 gtagattatt atgagactat tgaaaattta gagagaagtt taccaacaaa tttttttagg
      601 tgtcatcgta gttatataat caatttacaa tatgtatatg gatatgaaaa tggtaatgca
      661 gttatggaaa gtggagatag aatacctgtt tctagactac gtcaacaaat attttcaaaa
      721 gttatgcttg agttcatgaa aaataggagg atataagatg attaatttat tttcttccga
      781 tttattttta aagtacagtt ttttattttc ttttattgta tatagaattt taatggtaat
      841 agtgcaatac tattttctaa tcagttttac aaatgttaat tcaaaatttt ggtgttttat
      901 tttatattcg ataatttcaa tttttttaat cattataaat acatatttta atttatataa
      961 tttattttct tcacagattc tattttttct tatgactttt ttatttgtaa agtacataat
     1021 aaaacaatct actgttttat ctatagtatc aactttgtta gtatatttaa ttgaacaatt
     1081 agtatatgga tttacagctc cattaaatta cttgatattt actagtgata taaatacaga
     1141 tatttataaa tttgatataa atatgggact atcttcttta attactatta taatagctgg
     1201 atttatatat tggtatagtt ctaaaaagtt taatattaag gtcatgaact ttgataaata
     1261 tatagcaatt ttgatgattc cattgttgct tataatatta tttatgcaat catttgaata
     1321 tagttcaaat ataaatatag atacaagtct tgggattgta aagctgctat taaatacttc
     1381 tataactgaa gaaattcaag cttttctttt ttctataatt ggaactatat gtgtattttt
     1441 ttctctattt acctttaaga aactaattca agctctcgaa gatgacaagg agagggcaat
     1501 tatgaatcaa cagattcatg ctcaaaaaaa ctatattgaa gaagcgaaat cacgattatc
     1561 acaaactata tcctttagac atgattttaa taatcattta gctattgtca atggattgtt
     1621 gaaaaaagac caaattttaa aagcacaaga ttatttaaat aagcttgaaa aagtaacaag
     1681 tgacctatca ttttcttgta atacacagaa tattgttatt gatgctcttt tcaacaataa
     1741 attaagtata gcaaaacaat taggcataga ggtagattgt gaagtaatta taccccaaag
     1801 cactaacatg aacgattttg acctatgtat agtgtttgct aatgctattg acaatgcaat
     1861 taaagcttgt agagttgtag ataaacaaaa taggtattta aagctttcca ctaagttaga
     1921 gggtggattt tttatgatag aaataaaaaa tagctataat ccaataaata attatacaag
     1981 tggctcaggt ataggtcttt taaatataaa agaaattgct aaaaaatatc aaggggctat
     2041 aagtatagat aagacatcag attattttca aataaatgta ttgctggtta tttcattaca
     2101 ttgcgctagt atttgataac aatttcattg aaaatagtat ttgtaagcta tattatgtac
     2161 ttgaatagag aaagtttgat atatagaaat gaggaggtta ctaaaatgaa agttggaaat
     2221 ataaatggtc aagcaccaat tacaaatggt ttagatagtt gtcaaagtga ggtacaaggc
     2281 ttagaacaaa agaaaaaatc attacaggat gaaatagaga aagtaagaag tgataaaagt
     2341 attgatggtg aaacagccaa attaaaaata gaagctttaa aaaaagaaat ggaagagatt
     2401 gaaaataaaa ttcaagagtt aaaaggaaat aaagcaaaaa aaacaaataa agaagaaaat
     2461 aatgtttcag aagtaaataa taatctatta gagagaaaaa aagaaccttc taataatgaa
     2521 aatgtaaaac aattatatga tgtttttgaa agaagcaatg tagacgaaca atgggataat
     2581 acttatcgtg ttctccaaga tgataaaaac ttaaaagtaa aatttaatag acctatatag
     2641 tttatttata aaaatagtta atattttaat tatcaccact ttttagaaga atacacactt
     2701 tattttaaag acccacatat ttatttacag ttagcacatt tatatgtggt tttataacta
     2761 ttatttacaa gtctatattg ataactttta catagtatat aatgtttaaa tacttattca
     2821 aatttatcta tacataaaca aaaaaagaga ttttaaaatc tctttttaga ttgttgactt
     2881 atggcttttt gatttaataa aatcaagaag ccgtttgaat tttatctgtt ggctgatacc
     2941 cttctgatat tgaaacacca tttttgtttc caaaatcgtt taaaattaag aacttattat
     3001 gaatgactat ttcattatga acaataagca gataacatga atcttcaatc aatgttttaa
     3061 cagtagcatt aaatgcttgc ttatacagtt ctatcgtttg tttgaactgt ccattaaagt
     3121 aaatatgagt caataacata actatatcta cacaaattaa tataaatttt ttatactgta
     3181 cattatctaa ctgttgatta tctgtatta
//
LOCUS       DAJMZY010000197         3092 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.202, whole genome shotgun sequence.
ACCESSION   DAJMZY010000197 DAJMZY010000000
VERSION     DAJMZY010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3092)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3092)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3092
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.202"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            complement(519..1271)
                     /locus_tag="OE968_003704"
     CDS             complement(519..1271)
                     /locus_tag="OE968_003704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TSUP family transporter"
                     /protein_id="HCP7220930.1"
                     /translation="MFSVIFLCIGGFLAAFVDSIAGGGGLISMPVLMAIGVPVHLAIG
                     TNKFAASAGCISSAYRYAKSGKINNNLLKKLVPFTIIGSVLGVRCVLSISEEILNVLV
                     VAMILIVAIYTFISKNLGQEDNFEAVNKKNLRLGMLMALIMGFYDGFFGPGTGTFLTF
                     GFIKIYGYDFLHASANTKILNLTSNITSLLLFMINGQVDYKIAIVFALVMIMGAYVGA
                     KVAIKKGSKMIKPIFLVMALFMVVKLVYQTLV"
     gene            complement(1330..2985)
                     /locus_tag="OE968_003705"
     CDS             complement(1330..2985)
                     /locus_tag="OE968_003705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCP7220931.1"
                     /translation="MVDFIESNNEVQKFDWGEVMWIHEPSKTQFNRLSAGIVRFFPGN
                     CQEKHFHLSEEQLLYVIQGEGIQIIDGKKVNIKETSIVYCPPYSEHEIINTGKIDLVI
                     LITYVPHKFSSLRQIPIVFSENNIQELVNVNIIENLANQISNILKLRISVYDLKYKEI
                     FETKKENKFCDICKNIKPCTKKLVKSINNDNFEKVYHCEYGVSSLEIPIVLEENIVGY
                     IECGNFIVYKSIYIDKNLSELSSSSGIDIKYINKIYNEFPLNPKSRLYVLKENLLMMS
                     EFIQEIAKRNFFENQLSIKDEEILKSRKENIRLEEALKKANSRLLEEEYIINPIDMFN
                     NSSKEYPFELELYIEKEIKNMNLEGVYNLIDTNKLRYNDVRDTIQEMIFVLSRTVLRD
                     LEDLKLISYLRNKYNKKISLVNSDEDLWNVLFEFSKECIDKNRAFWRKDKGNLIENIN
                     EYIKKYYKENINLNSISDVFFISPNYLSSIFNERNKVSITEYINLLRIEESKKYLLDR
                     SMSVSDICKKVGFNNSSYFSQIFKKFNSITPNEYRKNMLDNKY"
BASE COUNT         1070 a          510 c          257 g         1255 t
ORIGIN      
        1 tagccttgtt aaatatagat ttgaatatga atttaaagtt atgtaaaatt aaaaatacag
       61 gaatgaaaat tccattcctg tataaaatct aacttttgag tctcagtaca atcttatttt
      121 gagacaatct tttttgtttt atattttctt atatttaaaa tataacgcat atcttatgca
      181 acatattcat atttttcttt atattctttc atcgcatcat tccaagcgtc ttgtactgtt
      241 acacctcttt tattagcaat tttttgtgcc agttcaatta tcttcatagc tcttcttgat
      301 atgttcataa acattcctcc tacaaattac catatatttc atatatataa atcaaggtta
      361 tatttttatg atatataatc cttctattgt aagattacag tttatatgtg tattatatat
      421 gaactatatt agaagataat tagaattttt ataaagctat atgattagat taaatataaa
      481 agctttacaa ttacttataa atttaaaaag tctataaact aaactaatgt ttgatatacc
      541 aattttacga ccataaataa tgccattact aaaaatattg gttttatcat ctttgaacct
      601 ttctttatag caactttagc acctacataa gctcccatta tcatcactaa tgcaaacact
      661 atagcaattt tataatctac ttgaccattt atcatgaata ataacaatga agttatatta
      721 cttgttaagt ttaatatttt tgtatttgca gaagcatgta aaaaatcata tccatatatt
      781 tttataaatc caaaagtcaa aaaagttcct gtacctggac caaaaaaacc atcataaaaa
      841 cccattataa gagccataag catccctagt cttaaatttt tcttattaac agcttcaaaa
      901 ttatcttctt gacctaaatt tttagaaata aaggtgtaaa tagccactat taaaatcata
      961 gccacaacca aaacatttaa tatctcttca cttattgata atacacatct cacacctaga
     1021 acactaccaa taatagtaaa tggtactaat ttttttaaaa ggttgttatt aatttttcca
     1081 gactttgcat atctataggc actacttata catcctgctg atgctgcaaa tttatttgta
     1141 ccaatggcaa gatgtactgg cactccaatt gccataagaa caggcatgct tataagtcct
     1201 cctcctcctg ctatagaatc tacaaaagca gctaaaaacc cccctataca taaaaaaata
     1261 actgaaaaca taaaattcct ccatcattct ctttcaattt ttcttacaat atatattata
     1321 taatcttatt taatacttat tatccagcat attctttcta tattcatttg gagttatact
     1381 attaaacttc ttaaatattt gtgaaaaata actactgtta ttaaaaccta ctttcttaca
     1441 aatatcacta acactcatgc ttctatctaa cagatatttt ttagattctt ctatcctaag
     1501 aagatttata tactcagtta ttgaaacttt atttctttca ttaaaaatag aactcaaata
     1561 atttggactt ataaaaaaaa catctgatat actattcaaa tttatatttt ctttataata
     1621 tttttttata tattcgttta tattttcaat tagatttcct ttatcttttc tccaaaatgc
     1681 tctattctta tcaatacact ctttggaaaa ttcaaataat acattccata aatcttcatc
     1741 actgtttaca agtgatattt ttttattata tttatttctt aaataagata taagttttaa
     1801 atcctctaaa tctctaagca ctgttctaga caatacaaat atcatttcct gaatagtatc
     1861 tctaacatca ttatatctta atttgtttgt atctattaga ttataaacac cttctaaatt
     1921 catattttta atttcttttt caatataaag ttctaattca aagggatatt cttttgaaga
     1981 attattgaac atatctatcg gattaataat atactcttct tctaataatc tactatttgc
     2041 ttttttaagt gcctcttcaa gtcttatatt ttcttttcta ctcttcaata tctcctcatc
     2101 ttttatacta agttgatttt caaaaaaatt cctcttagct atttcctgaa taaattcaga
     2161 catcattaat aaattttctt ttaatacata taatctactt ttaggattta atggaaattc
     2221 attgtaaatt ttgtttatgt attttatatc aataccagaa ctacttgata attcagataa
     2281 atttttatct atataaatag acttatatac tataaaatta ccacattcta tatatccaac
     2341 tatattttct tctaatacta taggtatctc taaactggaa acaccatact cacaatgata
     2401 cactttttca aagttatcat tatttatgct tttaacaagt tttttagtac acggttttat
     2461 atttttacaa atatcgcaaa atttattttc tttcttagtc tcaaatattt ctttatactt
     2521 taagtcatat acagatattc taagcttcaa tatattagat atttgatttg caagattttc
     2581 aattatgttt acattaacta actcctgtat attgttttca gaaaatacta taggtatttg
     2641 tctcaaactc gaaaatttat gaggaacata agtaattaat attactaaat caattttacc
     2701 agtgtttata atttcatgtt ctgaatatgg tgggcaataa actatagatg tttcctttat
     2761 attgaccttt ttaccatcaa ttatttgtat tccttctccc tgaatcacat ataaaagctg
     2821 ttcttcactt aaatgaaaat gcttttcttg gcagtttccc ggaaaaaatc ttacaattcc
     2881 agcactaagt ctattgaatt gtgtttttga tggttcgtgt atccacataa cctctcccca
     2941 atcaaatttt tgtacttcat tatttgactc aataaaatcc accataaact cacctcgtag
     3001 tttttgtcta aatatttttt cttcccttct tatattaaaa taatatcatc atcattaact
     3061 ttcattacta taaaatcatc atactctttt aa
//
LOCUS       DAJMZY010000198         2980 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.203, whole genome shotgun sequence.
ACCESSION   DAJMZY010000198 DAJMZY010000000
VERSION     DAJMZY010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2980)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2980)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2980
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.203"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            <1..849
                     /locus_tag="OE968_003706"
     CDS             <1..849
                     /locus_tag="OE968_003706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HCP7220932.1"
                     /translation="VTYFVERGNSFVQEFLYDEYGKMTDIQEGHFRINNKEQGWGKVP
                     FISFKNNEKCVSDLTFYKSLIDIYDNNISTLADNLDEIQEVIYVLKEYPGTSLQEFID
                     NIRYYKSIKVDGGGGVDKLEINIPVEAKKELLDRLEKNIIIFGQGVNPESQNTGDKSG
                     VALKFLYSLLDLKCSKTEKKFKKAIRELLWFVCEYLKISGSKSYDYKTVQITFNHSMI
                     INEAEKIDMAAKSTGIVSDETIVSNHPWVEDVNDELERLKKQEDTQKEYDDLIPNNQD
                     GVIDET"
     gene            839..2236
                     /locus_tag="OE968_003707"
     CDS             839..2236
                     /locus_tag="OE968_003707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HCP7220933.1"
                     /translation="MKHKDYWRKRFEQLEEAQNNKSVKYYLELEKQYKLAMNSIEKDI
                     LAWYNRFAKNEGISLLEAKKLLNTRELEEFKWSVEEYIRHGKENAINQKWMKELENAS
                     ARVHITRLEALKLQIQQQVEVLYGNELDSVDKLMRDIYTSGYYHTAFNVQQGVNVGWS
                     LMSLDTNRINKVISKPWTSDGLNFSERIWGKHRPALINELHTKLTQSIIRGENPKNLV
                     NDFAKSFNVSKSQAKNLIMTESAFFASASRKDCFNDLDVEKYEIIATLDLRTSNICRE
                     LDGKVFDMKDYQVGITAPPFHCRCRTTTAPWFEDEEGYRAAKGEDGKTYYVPSSMKYN
                     EWYEKYVKHNSILEIKNSAIIDSIKEDIKNGKYNLNIHDGKQGKHLKEHNNYIEGRSY
                     LTITKEEAQELVNKHAGNGIIKFNRSGEWDKKELIEVDKNIGVNVNNITGEKTLTNKF
                     KIHYSKTGTHIVPAL"
     gene            2251..2451
                     /locus_tag="OE968_003708"
     CDS             2251..2451
                     /locus_tag="OE968_003708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220934.1"
                     /translation="MKLWEYVGKNVQITCVDKQIIRGKCDGYTQALDNEPEIASISIA
                     RDGYGIEVYENEIESIENINKE"
     gene            2517..>2980
                     /locus_tag="OE968_003709"
     CDS             2517..>2980
                     /locus_tag="OE968_003709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage scaffolding protein"
                     /protein_id="HCP7220935.1"
                     /translation="MDWLKELLEGIKIEDNKIDVASLQKSIEKKIKETTITQEDYTNL
                     ETQLNTANETIKKFEGGMTKEDVENLKTTYETDKKTLEETYKKEIEEKDFNYWLNDAF
                     KSIKCRDEIALKAHLDIEALRNSKDRQKAFEEQINPLKQDKDYLFNATLEGE"
BASE COUNT         1288 a          288 c          561 g          843 t
ORIGIN      
        1 gtaacttact ttgttgaaag aggtaatagt tttgttcaag aatttttata tgatgaatat
       61 ggaaaaatga ctgatataca agaaggtcat tttagaataa ataacaaaga acagggatgg
      121 ggtaaagttc catttatatc ttttaaaaat aatgaaaagt gtgtctcaga tttaactttc
      181 tataaatcat taatagatat atatgacaat aatatttcta cactagcaga taacttagat
      241 gaaatacaag aggttattta tgtattaaaa gaatatccag gaacaagtct acaagagttt
      301 atagataata taagatacta taaatcaatt aaagtagatg gtggaggtgg agttgataaa
      361 ctagagataa atataccagt tgaagctaaa aaggagcttc ttgatagatt agaaaagaat
      421 ataattatct ttggtcaagg agttaatcca gaatctcaaa acacaggtga caaatcgggt
      481 gtagcactta aatttttata ttcattactg gaccttaaat gttctaagac tgaaaagaag
      541 tttaaaaaag caattagaga gcttttatgg tttgtgtgtg agtatttaaa gataagtggt
      601 agtaagagct atgattataa aacagttcaa attactttta atcactctat gataataaat
      661 gaagctgaaa agatagatat ggcagctaaa tcaactggaa ttgtatcaga tgaaactatt
      721 gtttctaacc atccttgggt cgaggatgta aatgacgaac ttgagagact taaaaaacag
      781 gaagatactc aaaaagagta tgatgattta attcctaata atcaagatgg tgttatagat
      841 gaaacataaa gattattgga ggaagagatt tgaacaatta gaagaagctc aaaataacaa
      901 aagtgtaaaa tattatcttg aattagaaaa gcaatataaa ctagctatga atagtataga
      961 aaaagatata ttagcatggt acaacagatt tgccaaaaat gaaggaatat ctttattaga
     1021 agctaagaaa ctactaaata caagagaact agaagagttt aaatggagtg tcgaagaata
     1081 tattagacat ggtaaagaaa atgctataaa tcaaaagtgg atgaaagagt tagaaaatgc
     1141 tagtgcaaga gttcatataa caagacttga agctttaaag ttacaaatac agcaacaagt
     1201 agaagtttta tatggaaatg aattagatag tgttgataaa ctaatgagag atatttatac
     1261 aagtggatac tatcatacag cttttaatgt tcaacaagga gtaaacgttg gttggagttt
     1321 aatgagtctt gatactaata gaataaataa agttatctct aaaccatgga ctagtgatgg
     1381 attaaatttt agtgaaagga tttggggcaa acatagacct gctttaatta atgagttaca
     1441 cactaaattg acacaatcaa ttattagagg tgagaatcca aaaaatctag tcaatgactt
     1501 tgctaagagc tttaatgtat ctaaatcaca agctaagaat ttaataatga ctgaatcagc
     1561 tttctttgca tcagcaagta gaaaagattg ttttaatgat ttagatgtag agaaatatga
     1621 gattattgct acattagatt taagaacttc aaatatatgc agagagttag atggaaaagt
     1681 atttgatatg aaagattatc aagttggaat aacagctcca ccatttcatt gtcgttgtag
     1741 gacaacaaca gctccttggt ttgaggatga agaaggttac agagcagcaa aaggagaaga
     1801 tggaaaaaca tattatgtac catctagtat gaagtataat gagtggtatg agaagtatgt
     1861 taaacataat agtatcttag aaataaaaaa tagtgctata atagatagca taaaagaaga
     1921 tattaaaaat ggtaaatata atttaaatat tcatgatggg aaacaaggaa aacatttaaa
     1981 agagcataat aattatatag aaggaagaag ctatttaact ataacaaaag aagaagctca
     2041 agaacttgtg aataagcatg ctggcaatgg aatcataaaa tttaatcgaa gtggagaatg
     2101 ggataaaaaa gaacttatag aagttgataa gaatataggg gtcaatgtta ataatattac
     2161 gggtgaaaaa actcttacaa ataagtttaa gatacattat tccaaaactg gaacacatat
     2221 agtaccagct ttataaggag gaaaaataaa atgaaattat gggaatatgt agggaaaaat
     2281 gttcaaataa cttgtgtaga taagcaaata ataagaggaa agtgtgatgg atatacacaa
     2341 gctttagata atgaaccaga aatagcaagt atatcaatag ctagggatgg ttatggaatt
     2401 gaagtttatg aaaatgaaat agaatctatc gaaaatataa ataaggaatg actaagcatg
     2461 tacttaaaaa taagtagatg cttttatttt gtaaaaaatg aaaggagaaa tttaaaatgg
     2521 attggttaaa agaattgcta gaaggaataa aaatagagga taacaagatt gatgtagctt
     2581 ctttacaaaa gtctatagaa aagaaaataa aagagactac aattactcaa gaagattata
     2641 caaatcttga aacacagctt aatacagcta atgaaactat taaaaagttt gaaggaggta
     2701 tgacaaaaga agatgtagag aatctaaaaa caacttatga aactgataag aaaactttgg
     2761 aagaaaccta caaaaaagaa attgaagaaa aggactttaa ttactggtta aatgatgctt
     2821 ttaagtctat taaatgtagg gatgaaatag cgttaaaagc tcatttagat atagaagcac
     2881 taagaaatag taaagataga caaaaagctt ttgaagagca aataaaccct ttgaaacagg
     2941 ataaagatta tttgtttaat gcaacactag aaggtgaaga
//
LOCUS       DAJMZY010000199         2957 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.204, whole genome shotgun sequence.
ACCESSION   DAJMZY010000199 DAJMZY010000000
VERSION     DAJMZY010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2957)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2957)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2957
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.204"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            complement(1046..2602)
                     /locus_tag="OE968_003710"
                     /pseudo
     CDS             complement(1046..2602)
                     /locus_tag="OE968_003710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860844.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein CwpV"
BASE COUNT          678 a          566 c          367 g         1346 t
ORIGIN      
        1 cttttaatgt tgcttttgat gcttctaaat tttctgctgt tacttttcct actagttttg
       61 ttacttctgc tattttttct tctgcttttg tctttgcttc ttctttagcc tgtgatgatt
      121 ctaatgcagt tatctcactt tgtacttttg ctatatctcc atatcctgca aaactttgaa
      181 cttctgattc tgtccaccct gctgcctttg cttcttctat tgcatcagtt gccgctttta
      241 atgttgcttt tgatgcttct aaattttctg ctgttacttt tcctactagt tttgttactt
      301 ctgctatttt ttcttctgct tttgtctttg ctgcttcttt agcctgtgat tctaattcag
      361 ttatctcact ttgtactttt gctatatctt catatcctac aaaactttga atttctgatt
      421 ctgtccatcc tgctgccttt gcttcttcta ttgcatcagt tgccgctttt aatgttactt
      481 ttgatgcttc taaattttct gctgttactt ttcctactag ttttgttact tctgctattt
      541 tttcttctgc ttttgtcttt gcttcttctt tagcctgtga tgattctaat gcagctatct
      601 caccttgtac tgttgctata tcttcatatc ctgcaaaact ttgaacttct gattctgtcc
      661 atcctgctgc ctttgcttct tctattgcat cagttgctgc ttttaatgtt acttttgatg
      721 cttctaaatt atctgctgtt acttttccta ctagttttgt tacttctgct attttttctt
      781 ctgcttttgt ctttgctgct tctttagcct gtgattctaa ttcagttatc tcactttgta
      841 cttttgctat atctccatat cctttaaagc tttgaacttc tgattctgtc caccctgctt
      901 tccttgcttc ttctattgca tcagttgctg cttttaatgt tacttttgat gcttctaaat
      961 tatctgctgt tacttttcct actagttttg ttacctctgc tattttttct tctgcttttg
     1021 tctttgtttt tgacttatcg cttggttttg atgaagaact tcctcctcca tgtgaagagc
     1081 ctccacttga tgaacttcct cctgaagagt tagaacttgg actatttcca cttattgttg
     1141 gagaattatc tcccttaaca ctacttattg tacctttatt atctatagta gtccctttag
     1201 aattatttgt aactgtagtt atcttaccac cattagtcac ttttacttga cttgctccag
     1261 atgctactgt taaactacca atctcacctt tagaattatt ttctatcttg gctccatttt
     1321 tatcattaac ctttaagtta gttatttttc catagttaac aaaagttcca tcttttacat
     1381 catctataac tacatcatcc acttttgcat agttatttac atctccatta ggcatgttga
     1441 tagttacagt ctttgtatat gtaccattta agtttactgt tactgcttta tcagtttgta
     1501 ttgtaaatgc ttctttaacc tcactagttg gcttaaagtt tataacatca ttagcagtag
     1561 ctttatctat agctgatttt aattcagaaa ttgttttagc ttcaactgtt tttacttctt
     1621 gtaatgactt catttcatta aatgctgtct cattaccatt cccaccaact ttagttatct
     1681 tatcaaaact cttagagtta actagagatt tttgtgaagc tgataagttc tttccaacta
     1741 aaactactgg tgattgattt ttagcaccta atacacctac tgctagtgca tctataagtt
     1801 ggtcttgttt attcatacca tctttagtta cataagcatt ttttaaatct gtctttttat
     1861 aaaattcttt tattactttt gcatttgtat catttctatc tgttccacct agtcttgtac
     1921 tatttggtag tttattttta acagcttcag aaattgaact ctctccacct actacataag
     1981 attgagttat tccagcatct tttataaatt tgtctgcaac tgctgttcca tttttagaat
     2041 cagcaagtat tactggcata ttgttttgtg cagctggtgc tcctacactt acagcatctg
     2101 caagtccttt ttcaccatta actacagcta ttttcttaac atcacttata gcatctaatt
     2161 tctttgctaa ttctaaggat gtttgatatc tctcagctcc agagattctc tcaaaagata
     2221 tttttaaatc ttttatttct ttttctatat ttgtacttaa tacagaagtt ccacctatta
     2281 agtatacttt tttagctttt aatctttgta tttctgcttt cgtcttatca tttaatttat
     2341 ctttacttgt taaaagtatt ggagcatttt ttgcttttgc aaatggtgtt gcagatagag
     2401 catctgctat agatgagtcg tttacgatta ctacctcatc agcatttttc catccatctt
     2461 gacttatttt aacagcagtt tcatatcttt cttgccctgt taaatttgtt gccacagttt
     2521 gtgcactagc tatgcctgct gttgaacttc cagctatcat tgtaactgta agcattgcag
     2581 caatcttctt tggtattttc attttatttt cttccccctt gtccatttga tattacttaa
     2641 ttttttaact ttgttcccgt tctaattcta aaggatactt aatatctaat tttaaagagg
     2701 tttctaacta taatgatttc ataattaatt tgtaattatt ttgttacatt gcagtcatta
     2761 tgtaaggaat aaagaaattt tcttattgat tgaaaaattt gtaaatttat attttaaggt
     2821 aagtttgatt tttatgttaa tgaattgtta taaaaaatag ggttttgtat aaaaaaagta
     2881 gcctttatga attaaagtgc tactcttttt acaaataaat tttattattt atacttgtaa
     2941 ttatatatta aataacc
//
LOCUS       DAJMZY010000200         2853 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.205, whole genome shotgun sequence.
ACCESSION   DAJMZY010000200 DAJMZY010000000
VERSION     DAJMZY010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2853)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2853)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2853
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.205"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            192..1469
                     /gene="hflX"
                     /locus_tag="OE968_003711"
     CDS             192..1469
                     /gene="hflX"
                     /locus_tag="OE968_003711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HCP7220936.1"
                     /translation="MDMAKKGITVGLNINNKSEDFNELMIELENLCSACDIDVVGSIT
                     QNAKQVNRAFYIGTGKVEEILNLIKKENIEIVIFYNELSTSQLKNLEEKLNCEIIDRT
                     ALILDIFAQRAKTREAKLQVEVASLKYMLPRLIGSNENLGRQSGGVGTKNRGSGEKKL
                     ELDRRRIEEKITSLNRELDDLKFQRETQRSMRRKSNLPNVALVGYTNAGKSSIMNKLV
                     DIFKNSEEKKVFEKNMLFATLETSVRNIVLANNKEFLLSDTVGFVSNLPHDLVKAFRS
                     TLEEACEADVLLHVIDISNPSYKSHIKVTEDTLKQIGADGIPMIHVYNKIDLIDVDVL
                     DRILDSIDKEGIFVSVKKDINIDKMIKCICDSIFKDYVRCKFLIPYDKGHVVSYFNEN
                     MSIINTEYREDGAILDVECSNIEYNKYKKYALE"
     gene            1702..2199
                     /locus_tag="OE968_003712"
     CDS             1702..2199
                     /locus_tag="OE968_003712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HCP7220937.1"
                     /translation="MDAETLMKKYMVDDDSRKQAIFASIFVMQNKLQTTCDKLDPELT
                     MKQWLLLAIADSVDETLTLTKLGELMGCSRQNVKKLAIALEKKGFIQIEQNEKDSRAI
                     CLVTKDRVQEYSKKVRGMQEKVLQLLFEDFTEKEVEQLFFGIMKLSIGIENVKNYVEN
                     NDVGE"
     gene            2249..2773
                     /locus_tag="OE968_003713"
     CDS             2249..2773
                     /locus_tag="OE968_003713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HCP7220938.1"
                     /translation="MKNVVVIYKSKYGSTKKYAKWLSELLSCDIFETKNINIEKVMKY
                     DTIILGGGLYACNIAGISFLKKNYKELQKKNLVVFGVGAAPYDDEVIKKLREVNFKDE
                     LNKIPCFYCRGAWDETKMSFIDYTLCSFFKKSIAKKERQGLKPAEAPLLSGEAFDWCN
                     KENLTPILDYIREL"
BASE COUNT         1190 a          254 c          509 g          900 t
ORIGIN      
        1 atttgggagg aggtgtaaga aagtgatttt ttatataaga ttgagaaaat aatgcacgat
       61 tatggttatt ataatagtaa ataagaagtg tcatttaagg ataagataaa aagcaaaatt
      121 cttgatgaat ttaattatag agccataatc tcgtgctata gattaaataa aaaatagcag
      181 ataaggagaa tatggatatg gcgaaaaaag gaataacagt aggattaaac ataaataata
      241 aatctgagga ctttaatgaa ctaatgattg aacttgaaaa cttatgttca gcatgtgata
      301 ttgatgttgt agggagtata actcaaaatg caaagcaggt taatagagca ttttacattg
      361 ggacaggtaa agttgaggaa atattaaact taataaagaa agaaaatata gagatagtta
      421 tattttacaa tgaactttct acatcacaac taaaaaatct tgaagaaaag cttaattgtg
      481 aaattataga tagaacggca ttgatacttg atatatttgc acaaagggca aaaactagag
      541 aagctaaact tcaagtagaa gtagcaagtt taaaatatat gttaccaaga cttataggtt
      601 caaatgaaaa tttaggacgt caaagtggtg gagttggtac taaaaataga ggttctggtg
      661 agaaaaaatt agaacttgac cgtagaagaa tagaagaaaa gataacatct ttaaataggg
      721 agttggatga tttaaaattc caaagagaaa ctcaaagaag tatgagaaga aaatcaaatc
      781 ttccaaatgt agctctagtc gggtatacaa atgctggtaa atcttcaata atgaataaac
      841 tagtagatat atttaaaaac tctgaagaaa agaaagtgtt tgagaaaaac atgttatttg
      901 ctacacttga aacttctgtc agaaatatag ttcttgcaaa taacaaagaa tttttattat
      961 ctgatactgt tggttttgta agtaatctac cacatgactt agtaaaagca tttaggtcaa
     1021 cattagaaga agcatgtgag gcagacgtac tgttacatgt tattgatatt tcaaatccaa
     1081 gctataaaag tcatattaaa gtgacagaag atactttaaa acaaataggt gcagatggta
     1141 tacctatgat acatgtgtat aataaaattg atttaataga tgtagacgta ttggatagaa
     1201 ttttagatag tattgataaa gaaggtatat ttgtttcagt taaaaaagat ataaatatag
     1261 ataaaatgat aaaatgtatt tgtgatagca tatttaaaga ttatgtaaga tgtaagttct
     1321 taattccata tgataaaggt catgtagttt cttattttaa cgaaaatatg agcattataa
     1381 atacagaata cagagaagat ggagctattt tagatgtaga atgtagcaat atagaatata
     1441 ataagtataa aaagtatgct ttagagtaaa ttttgaaaaa cttattatag cctaaaatat
     1501 atttaattta taatttatta taaattgatt gtaaatatga ttttatgaaa cggtatagcc
     1561 ataatgctat gccgttttgc catttataat aaaaataaat ttattgacat aatagtaact
     1621 aattactata atataaagta attagttact atttaaaatt atcaaaaaat taaaatctaa
     1681 gataaagaga agtgtataat aatggatgca gaaactttaa tgaaaaaata tatggtagat
     1741 gatgatagta gaaaacaagc tatatttgca agtatatttg taatgcaaaa taaacttcaa
     1801 actacatgtg ataaattaga cccagaatta acaatgaaac aatggttact tttagctatt
     1861 gcggactctg tagatgaaac tcttacatta accaaacttg gagaattaat ggggtgctca
     1921 agacaaaatg taaaaaaact agctattgct ttagaaaaga aaggttttat acaaattgag
     1981 cagaatgaaa aagattcaag agctatctgt cttgtgacaa aagatagagt gcaagagtat
     2041 tctaaaaaag taagaggtat gcaggaaaaa gtattacagc ttttatttga agattttaca
     2101 gagaaagaag tggaacagtt attttttgga attatgaaat taagtatagg aattgaaaat
     2161 gtgaaaaatt atgtagaaaa taatgacgtt ggagaataag caagtatcaa atcaactttg
     2221 tatgacatca gagaggggga taatttatat gaaaaatgta gtagtgattt ataagagtaa
     2281 gtatggttca acaaaaaaat atgctaaatg gctttcagaa ttattgtctt gtgatatttt
     2341 tgaaactaag aatattaata tagaaaaggt tatgaagtat gatacgatta ttttaggagg
     2401 aggtctttat gcttgtaata tagcgggaat ttctttctta aaaaaaaatt ataaagaatt
     2461 gcagaaaaaa aatttagtag tatttggcgt aggagctgct ccatatgatg atgaagtaat
     2521 aaagaaatta agagaagtaa attttaagga tgaattaaac aaaattcctt gcttttattg
     2581 tcgtggggca tgggatgaga caaaaatgtc ttttatagat tatactcttt gtagtttttt
     2641 taaaaaatct atagctaaaa aagaacgtca aggtcttaaa ccagcagaag cacctttatt
     2701 gtctggagaa gcatttgatt ggtgtaataa agaaaattta actccaatac ttgattatat
     2761 aagagaactt taagaggtat atatttataa ttatttatta tctaaagtta gatttcatag
     2821 aaacttacta gacattattt ataaaataat att
//
LOCUS       DAJMZY010000201         2837 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.206, whole genome shotgun sequence.
ACCESSION   DAJMZY010000201 DAJMZY010000000
VERSION     DAJMZY010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2837)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2837)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2837
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.206"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            292..795
                     /locus_tag="OE968_003714"
     CDS             292..795
                     /locus_tag="OE968_003714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MogA/MoaB family molybdenum cofactor
                     biosynthesis protein"
                     /protein_id="HCP7220939.1"
                     /translation="MFNVAIITLSDKGYEGKREDITGKKLTEFVENTGAYKVTEYVLI
                     KDDKEMLKENIIRLCNSNKIDLILTNGGTGFSKRDITPEATKEVLEKEIPGLSEYMRM
                     KSTEITKKAILSRGVSGIRNNSIIINLPGSPKGAVENLSFIIDVLDHGIEVLRGEATE
                     CATKKSE"
     gene            842..1801
                     /gene="moaA"
                     /locus_tag="OE968_003715"
     CDS             842..1801
                     /gene="moaA"
                     /locus_tag="OE968_003715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP 3',8-cyclase MoaA"
                     /protein_id="HCP7220940.1"
                     /translation="MIDKYGRKIDYLRISLTDKCNLRCVYCMPPDVKFDKNYINENLS
                     FEDYKFIIKAMAEQGITKIRFTGGEPLLYPKLNELIKFTKEECGINNIGMTTNAIGLS
                     DRIFELEKCGLNKVNISLDSLKEYKYKSVTRGGNLKDVLKSIESCLNLGIKVKLNCVA
                     ISGFNDDELKDFMFLTVKSPIDVRFIELMPLGEANRVYKKGYFNVKEMIEKIYGLYKV
                     KNDEKSTAEYYMFKGAKGRIGIITPLSCSFCNTCNRIRLTSSGAIKLCLHSKEEIDIK
                     PFLHKPLLFRESMKDIIKQKPEKHHLIENKCSDTNRRMYEIGG"
     gene            1805..2275
                     /gene="moaC"
                     /locus_tag="OE968_003716"
     CDS             1805..2275
                     /gene="moaC"
                     /locus_tag="OE968_003716"
                     /EC_number="4.6.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic pyranopterin monophosphate synthase MoaC"
                     /protein_id="HCP7220941.1"
                     /translation="MLTHINEKGYAKMVDISEKDDTKRTAVATATITLSKEALEKVKN
                     GQIKKGDVLSVAQVAGIMGAKNTSSNIPMCHQIKLVGCDLEFDVDDSMSAIKIYATCK
                     SLGKTGVEMEALNACSLAALTIYDMCKAVDKKMVISNIHLVEKTGGKSGDFKFE"
     gene            2311..2742
                     /locus_tag="OE968_003717"
     CDS             2311..2742
                     /locus_tag="OE968_003717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MOSC domain-containing protein"
                     /protein_id="HCP7220942.1"
                     /translation="MAKVVSINISEKKGVIKVPVQCAELKINHGIVGDAHAGNWHRQI
                     SLLGKESIDKMKMKGFDQLKYGDFAENVTTEGIEVFSLPVGTKLRIGQCEVEVTQIGK
                     KCHNGCEIKKLTGDCVMPREGIFVKVLKEGIINVNDSIDVI"
BASE COUNT         1187 a          254 c          541 g          855 t
ORIGIN      
        1 tttgtagaga aaaatatgga caatgttata ataattatag aaattaaaag tacttacatt
       61 cattatgtat gtgacatgta taattagttt tatatttaat acagttttga agtaatatct
      121 tcattttgag aacgttggaa taataaaaaa tgtattatta taggtgatat aaataaaaaa
      181 taaatataat atgttatatt gctgatagaa aagagaataa aagaaaatag gttttattaa
      241 aagagatttt tatttatagg acttaatcaa tgtatagagg ggtgagaaca tatgtttaat
      301 gttgcaatta taacacttag tgataaagga tatgaaggaa aaagagaaga tataacagga
      361 aaaaagttaa ctgaatttgt tgaaaataca ggagcttata aagttactga atatgtactt
      421 ataaaagatg ataaggaaat gctaaaggaa aatattataa gactttgtaa tagtaataaa
      481 atagatttaa ttcttacaaa tggaggtact ggtttttcaa aaagagatat aaccccagaa
      541 gcaactaagg aagtgttgga aaaagaaata ccaggtctga gcgaatatat gagaatgaaa
      601 tccacagaaa ttactaaaaa ggccatacta agtaggggtg taagtggaat aagaaataat
      661 tctataataa taaatttacc tggaagtcct aaaggtgcag ttgaaaatct aagttttata
      721 attgatgttt tagaccatgg catagaagtt ttaagaggag aagctacaga atgtgccact
      781 aaaaaaagtg aatagtatat aatctagata gataaaaaat agacaaagag gtagataaag
      841 tatgattgat aagtatggaa gaaaaataga ctaccttcgt atttcactta cagataagtg
      901 taatttaagg tgtgtttatt gtatgccacc agatgtaaaa tttgataaaa attatataaa
      961 tgaaaatcta agctttgaag actacaagtt tattataaag gctatggctg aacaaggtat
     1021 aacaaaaatt agatttactg gaggagaacc tcttttatat cctaaattaa atgagcttat
     1081 aaaatttaca aaagaagaat gtggaataaa taacatagga atgaccacta atgctattgg
     1141 gctttctgat agaatctttg agcttgaaaa atgtggctta aataaagtta atataagttt
     1201 agattctttg aaggaatata agtataaatc cgtaacaaga ggaggaaact taaaagatgt
     1261 cttaaaatcg attgaatctt gtttaaactt aggtataaaa gtaaagttaa attgcgttgc
     1321 tataagtggg tttaatgatg atgagcttaa agattttatg tttttaacag ttaaatcacc
     1381 aattgatgta agatttatag agcttatgcc attaggtgag gctaatagag tttataagaa
     1441 gggttatttt aatgtaaaag aaatgattga aaaaatatat ggtttatata aagtcaaaaa
     1501 tgatgaaaaa agtacagcag aatattatat gtttaaagga gctaaaggaa gaataggaat
     1561 tataactcca ttaagctgtt cattttgtaa cacttgtaat cgtattagac ttacttctag
     1621 tggtgcaata aaattatgtc tacattcaaa agaagaaata gatataaaac catttttaca
     1681 taaaccattg ttatttagag aatctatgaa agatataata aaacaaaaac cagaaaaaca
     1741 tcatttaata gaaaataaat gtagtgatac aaataggcgt atgtatgaaa ttggaggata
     1801 agtaatgtta acacatataa atgaaaaagg gtatgccaag atggtggaca taagtgaaaa
     1861 agatgatact aaaagaacgg ccgtagctac agctacaatt actcttagta aggaagcatt
     1921 agaaaaagta aaaaatggtc agataaaaaa aggagacgta ttgtctgtag ctcaagttgc
     1981 aggtataatg ggagctaaaa atacatcttc aaacatacca atgtgccatc agattaaatt
     2041 agttggatgt gatttagaat ttgatgtaga tgattctatg tctgctatta agatatacgc
     2101 aacctgtaaa tctcttggga aaactggagt agaaatggaa gctttaaatg catgttcttt
     2161 agcagcactt acaatttatg atatgtgtaa agcagttgat aaaaaaatgg ttataagtaa
     2221 tatccatctt gtagagaaga ctggtggaaa atcaggagat tttaagttcg agtaaattaa
     2281 taatatattg ggttaaaatt tggaggaaat atggcgaagg tagtgtcaat aaatataagt
     2341 gagaaaaaag gtgtaattaa agttcctgta caatgtgcag agctaaaaat aaatcatggg
     2401 atagttggag atgcacatgc aggaaactgg catcgtcaga taagcttact tggaaaagaa
     2461 agcatagata aaatgaaaat gaaaggcttt gaccaattaa aatatggaga ttttgctgaa
     2521 aatgtaacta cagaagggat agaagttttt tccctgcctg ttggtacaaa gttaagaata
     2581 gggcaatgtg aagttgaagt aactcaaata gggaaaaaat gtcacaatgg atgcgaaatt
     2641 aagaaattga caggtgactg tgtgatgcca cgagaaggaa tttttgtaaa ggttctaaaa
     2701 gaaggaatta taaatgtgaa tgattcaata gatgtaatct aatgaagtca ctattaaaat
     2761 ataattataa gtaaatacta ttaagattta aatatatatt ttaagagaga attaatttta
     2821 ataaaatatt ttagtta
//
LOCUS       DAJMZY010000202         2725 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.207, whole genome shotgun sequence.
ACCESSION   DAJMZY010000202 DAJMZY010000000
VERSION     DAJMZY010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2725)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2725)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2725
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.207"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            <1..1563
                     /locus_tag="OE968_003718"
     CDS             <1..1563
                     /locus_tag="OE968_003718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HCP7220943.1"
                     /translation="AFFEFTSVIICFNKSIKYEKIGLFELFKISFENSIKLLYPKNIL
                     LFIFVILIIPLVNTVLISGFIGKIQIPEYILDYIKSDIILNIIYMIFLLIIYISVIRW
                     IFSIHEITLNTENFKRARKESVNLIKGKIIRTIIYSLILSLVVAIIGYAIYHSGIIFI
                     GIWTKYCTDMEFLKNVFINRCIAFEEYFRLILSIFIFILDIGFISATYYQYKGVNISK
                     NNIKKEKKSISKIVFNLVLILLISYIESVAFSSHINGMFNTSFSFYTTAIAHRAGAEM
                     APENTLAAIEEASHAKADYAEIDVQETKDGELIVLHDSNFKRTTGVDKNVWDVNYNEV
                     KTYDAGSFYYYGKGYYDEKFVGEKIPTLKEMIKYSKGKVKLLIEIKLNGHEKGDVVKK
                     VVQLIKENNFENQCIVASMDKTILQKVKKLDENLLTCYFMAIAYGDFSKLNYVDIYGI
                     ESTFVNKTVVEKIHKMNKKIFVWTVNSDSLIEKMLDLNVDSIITDNPYLIESAIYWKK
                     NGFISQVSDYLF"
     gene            1885..2469
                     /locus_tag="OE968_003719"
     CDS             1885..2469
                     /locus_tag="OE968_003719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HCP7220944.1"
                     /translation="MTEREKMLAGELYDCGDIELLTQWHKAKDLVRDYNQTDSLDLEK
                     KEKILNELLGGKGKNLWITAPYYVDYGNNIYFGNNCEVNMNCTFLDDNKIIIGDNALI
                     APNVQIYTAFHPTNAGDRFGNAKEDGSFEFCKTQTAPVTIGDNVWIGGGAIIMPGVTI
                     GDNVVIGAGSIVTKDIPSNMIAYGNPCRIIRENK"
BASE COUNT         1061 a          255 c          427 g          982 t
ORIGIN      
        1 gcattttttg aatttacctc tgtaattatt tgttttaata aatcgataaa atatgaaaaa
       61 atagggttat ttgaactctt taaaatatca tttgagaact ctataaaatt gttatatcct
      121 aaaaatatac tattatttat atttgtgata ttaataattc cattagtaaa tacagtttta
      181 atttcagggt ttataggaaa aatacaaata ccagagtaca tattagatta tataaagtct
      241 gatataattt taaatataat ctatatgatt tttcttttaa taatatatat ttcggttatt
      301 agatggattt ttagcattca tgagataact ttaaatacag aaaattttaa aagagcaaga
      361 aaagaaagtg ttaatcttat aaagggaaag attataagaa caattattta ttcattaata
      421 ttatctttag tagtagctat tattggatat gcgatttatc atagtggaat tatatttata
      481 ggcatatgga ctaaatattg tactgatatg gaatttttga agaatgtatt tataaataga
      541 tgtattgcat ttgaagaata ttttagattg attttatcaa tattcatttt tatattggac
      601 attggattta tctcagcaac ttattatcaa tataaaggag taaatatttc taaaaataat
      661 attaaaaaag agaaaaaatc tatatcaaaa attgttttta atttagtatt aatattattg
      721 atttcttata tagagtcagt tgcattttct tcacatataa atggtatgtt taatacgtca
      781 ttttcatttt atacaacagc aattgctcat agagcaggag ctgaaatggc tccagagaat
      841 actttggcag caatagaaga agcttcacat gctaaagctg attatgcaga aatagatgtt
      901 caagaaacta aagatggaga acttattgta cttcatgatt caaactttaa gagaactaca
      961 ggagtagata aaaatgtttg ggatgtaaat tataatgaag taaagacata tgatgcggga
     1021 agcttttatt attatggaaa aggttattat gatgaaaagt ttgttgggga aaagatacca
     1081 acactcaaag aaatgataaa atattctaaa ggtaaggtga aattattaat agaaataaaa
     1141 cttaatggac atgaaaaggg agacgtagta aaaaaagttg ttcagttaat taaagaaaat
     1201 aattttgaaa atcaatgtat agttgcatct atggataaaa ctatattaca aaaagtaaaa
     1261 aaactggatg agaatttact gacatgctat tttatggcaa ttgcatatgg tgatttttca
     1321 aagttaaatt atgttgatat atatggaatt gaatcaactt ttgttaataa aacagtagta
     1381 gaaaagattc ataaaatgaa caaaaaaatc ttcgtttgga ctgttaatag tgacagttta
     1441 attgagaaaa tgcttgacct aaatgtagat agtattatta cagataatcc ataccttata
     1501 gagagtgcaa tttattggaa gaaaaatgga tttattagtc aagtgtcaga ttatttattt
     1561 taaatattct ataattgtat tatccagtaa aagagatatt attaaaatca ataatatctc
     1621 tttttaacat aaataaggtt gttaaattaa ggctattctt ataaaaattg tgtttatcag
     1681 atataaataa ggaataaaag taaaaaaatt gctatgacat tattacaatt aaaagagttt
     1741 taatatgata gagaggtaga ttgtcaactg tatatttaat aaattttatt atttattaga
     1801 ttttatataa gtaaaatata tagatatata aatcttatgc tagaatatat atgaaaaaca
     1861 atatagattt ggagggttaa aagcatgaca gagcgagaaa aaatgttggc aggagaactt
     1921 tacgattgtg gtgatattga gttgttaact caatggcata aagcaaaaga cctagtaaga
     1981 gattataacc aaacagattc cttggatttg gaaaaaaaag aaaaaatatt aaatgagtta
     2041 cttggtggta agggtaaaaa cttatggatt actgcaccgt attatgtaga ttatggaaat
     2101 aatatttatt ttggaaataa ttgtgaagtc aatatgaatt gtacgttttt agatgataat
     2161 aaaattatca ttggggataa tgcactaatc gcaccaaacg tacaaatata tactgcattt
     2221 catccaacta atgctggtga tagatttggt aatgccaaag aagatggttc atttgaattt
     2281 tgtaaaactc aaacagctcc agttactatt ggagataatg tttggattgg cgggggtgct
     2341 attatcatgc caggtgttac tattggagat aatgtagtta taggtgcagg aagtattgtt
     2401 acaaaagata ttccaagtaa tatgattgca tacggaaatc catgccgtat tattcgagaa
     2461 aataaataaa gttaaatttt cttgcaaaat ctcaaaaaac acctttctta ctttatacat
     2521 agggtatttt ctaatacttt cacatccata ttcatttgtt aaatttttgt ggaatgtagt
     2581 ttttatcact tctatcttac atttccacca tttttttata aaagtcattc ctttatagat
     2641 ttatttataa tagtatatat tctatttgat gtttgaataa gcacttattt ttaagtaaaa
     2701 tactaacttc taggttagta tttta
//
LOCUS       DAJMZY010000203         2560 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.208, whole genome shotgun sequence.
ACCESSION   DAJMZY010000203 DAJMZY010000000
VERSION     DAJMZY010000203.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2560)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2560)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2560
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.208"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            636..2432
                     /locus_tag="OE968_003720"
     CDS             636..2432
                     /locus_tag="OE968_003720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002594337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HCP7220945.1"
                     /translation="MKPTMEILTKLQENSKKNHDEVFTRLYRYLLRPDIYYVAYQHLY
                     SNKGAGTKGVTDDTADGFSEIYIENIIEALKNEMYQPKPVRRTYIKKSNGKMRPLGLP
                     VFTDKLIQEAIRMILEAIYEPIFSDYSHGFRPARSCHTALAQIKKEFTGARWFIEGDI
                     KGCFDNINHAVLVEIINQKIKDARFLKLIRSFLKAGYMEDWKYHKTYSGCPQGGIISP
                     ILANIYLNELDRHVMKIKKEFDVATKARYTPEYTKLVGLRQRLHNKIKNSNGIEREKL
                     IEEYKSATAQMLKLPAKQCDDKKIKYVRYADDFLIAVNGNRQDCEKIKQELTEFISTT
                     LKMELSQEKTLITHSNTPARFLGYDVRVRRDQQIKPKGKFKTRSMNNKVELSIPFKDK
                     IEKFLFSNGIVKQRSDNGKLEPIHRPQLLNRTDLEIVTIYNAELRGICNYYGLASNFN
                     KLIYFNYLMEYSCLKTLAGKHRSKVSKIRAMYKDGTGKWAIPYETKTVIKKMYFANYA
                     DCKGKKFTDIVPQTAKNYSHDVTTLESRLKAKICEVCGCTESDRYEIHHVNKVKNLKG
                     KSEWEKIMIAKRRKTIVVCHKCHMAIHHGEKK"
BASE COUNT          977 a          439 c          533 g          611 t
ORIGIN      
        1 ttagaagtag attaaagaaa gggggacaga aaaaaaaggc actaccccgt aagataacac
       61 gggaaaccac ctgcctaacc gaaaggtgaa aactgtacgg gaaaatagca cggcaggaaa
      121 gcagaaagtt gttcaaagac aatagagcac gactgaactg caaggttaag tgaatatgag
      181 gataaaacta gatttgttga atgtgagttc caaacctctg ttacgtgtgg acacaggaaa
      241 cttgtctgaa acctgtggta tgagtaacgc tgaaaataaa tgcctttcag tgggttatca
      301 attaactcat acggtacgct ggagaaccag tagtaacgga acgaaagcat atccgacaat
      361 tcacaccagc ctactacttt cgtcaactgg agattaccta aaccagaatg cctacaatgg
      421 ctatgtgtaa tgctcttgta gtgataaatc acaaggctat gctaagtgag atgacgctga
      481 aaatctggca aggtaacgga gctttcatag tagtctgaga accctgaaaa gacagggaaa
      541 gccgtaaaat cggatacggg aaaaccgttc acatggcgaa ggaaagcagt cttagcgaat
      601 taaaattaga aattgattag ggaggaaaac ctcaaatgaa accaacaatg gagattttaa
      661 ccaaattaca ggaaaattca aaaaagaacc atgatgaagt atttacaagg ctctatcgat
      721 atttactccg tccagatata tactatgttg catatcaaca cctctactcc aacaaaggag
      781 caggaacaaa gggtgtaaca gacgacacag cggacggttt tagcgaaata tatattgaaa
      841 atatcattga agccttaaaa aatgaaatgt atcaaccaaa accagtaaga cgtacataca
      901 tcaaaaaatc aaatggcaaa atgcgtccct taggactgcc tgtctttact gataagctga
      961 tacaggaagc aatacgcatg atattagaag caatctatga gcctattttt tcagactact
     1021 ctcacggttt ccgaccagca agaagttgtc atactgctct tgctcaaata aaaaaagaat
     1081 ttacaggagc acgctggttt atagagggcg acataaaagg gtgctttgat aacatcaatc
     1141 atgcggtact tgtggaaatt atcaatcaga aaattaaaga tgcacgtttt ctgaaactca
     1201 ttcgttcatt cttaaaggca ggttatatgg aagattggaa ataccacaaa acatatagcg
     1261 gttgccctca aggtggcatc atttcgccta ttcttgcgaa tatctacctt aatgaattag
     1321 accgtcacgt aatgaagata aagaaagagt ttgatgtggc aacaaaggca cgttatacac
     1381 cagaatatac aaaactggta ggactacgcc aaagattaca caacaaaatt aaaaatagca
     1441 acggtataga aagagaaaag ctgattgaag aatataaatc tgcaacggct caaatgctta
     1501 aactaccagc gaagcaatgt gacgacaaga aaataaaata tgtgcgttac gctgatgatt
     1561 tcctaatagc tgtgaatggc aatcgacagg attgtgagaa gattaagcaa gaacttacag
     1621 aatttataag taccacatta aaaatggaac ttagtcaaga aaaaactctg attacacaca
     1681 gtaatactcc tgctcgtttt ctcggatatg atgtcagagt acgccgtgac cagcagatta
     1741 aaccaaaagg aaaattcaaa acccgttcta tgaataacaa ggtggaattg agtattccat
     1801 tcaaagacaa gatagagaaa tttttatttt caaatggaat tgtaaagcag aggtcagaca
     1861 atgggaaatt agaacctata caccgaccac aactgcttaa taggacagat ttggaaatag
     1921 tgactattta taatgcagaa ttaagaggta tctgtaatta ttatgggttg gcaagcaatt
     1981 ttaacaagct aatctatttc aattatctta tggaatatag ctgtttgaaa acacttgcag
     2041 gaaagcaccg ttccaaagtt tctaaaatta gagctatgta taaagacggt acaggcaaat
     2101 gggctattcc ttatgaaact aaaacagtaa taaagaaaat gtattttgcg aattatgctg
     2161 actgcaaagg aaagaagttt actgatattg ttccacaaac agctaaaaat tattcccatg
     2221 acgtaacaac attagaaagc cgattaaagg cgaagatatg tgaagtatgt gggtgtacgg
     2281 aaagtgacag atacgaaatt catcatgtaa acaaggttaa aaaccttaaa ggaaaatcag
     2341 aatgggaaaa gataatgata gccaaaagac ggaaaacaat cgtggtatgc cacaagtgtc
     2401 acatggctat acatcatggc gaaaagaaat aacctgtaac ggagcaaaga tggagagccg
     2461 tgtgcattga gaaatgcaag cacggttcgg ggagaggact gcacaaacct accctagaaa
     2521 taaggaaagg cggtgctttc ctactctact atgtgggaaa
//
LOCUS       DAJMZY010000204         2515 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.209, whole genome shotgun sequence.
ACCESSION   DAJMZY010000204 DAJMZY010000000
VERSION     DAJMZY010000204.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2515)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2515)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2515
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.209"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            166..1785
                     /locus_tag="OE968_003721"
     CDS             166..1785
                     /locus_tag="OE968_003721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HCP7220946.1"
                     /translation="MNIVISLIGGLGLFLYGMSLMGEGLQKSAGDKLKKIIELLTSNV
                     VMGVLVGTVVTGIIQSSSATTVMVVGFVNAGIMNLSQAIGVIMGANIGTTVTAQLVSF
                     NLEGIAPIALGIGILFYLFTSNQKTKHLSEILIGFGILFTGMEFMKDAVAPLAEYKAF
                     TDALLYFSKNPVLGILAGFAITGIVQSSSASMGMLIALASQGILPLSSALPILYGDNI
                     GTCVTSLLSSVGASRNARRAAVMHLSFNVIGTIIFMLVLNKPISAIVTHFDPTDTARQ
                     IANAHTLFNLTNVIILLPFSKYIVKLANRLIPIKETESEIVNNTKYLDERMFSTPSIA
                     LGNTVQEVVRMGHKATNSLEHSIAGFLNKSNEDINKAFESEKVVNKLQKDILNYLLKL
                     SKEPLRDDEHFRTDLLFNTVNDIERVSDHAENIAELAMSVKEMNISFSDSAIREIYEI
                     YNKTITNFKDALIVLDVKDFELANKVLEVENEVNYLEKTFRNSHMIRLNNGSCTIDAG
                     VLYLDLLTNLERISDHSTNIVKQVLKLKQKI"
     gene            2159..2353
                     /locus_tag="OE968_003722"
     CDS             2159..2353
                     /locus_tag="OE968_003722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HCP7220947.1"
                     /translation="MINYMVEIIYSEKISEVENMLKIENIQYEFTSRDGFIFFGFYDM
                     TDAYRFETLCSDEKIRFKRI"
BASE COUNT          935 a          292 c          370 g          918 t
ORIGIN      
        1 aacaacaact taaaaattta acattctctt aacgtatact taacaaaaca ttaatatttt
       61 tattgacaaa atttgttatt ctatattatg gaaacaataa attttagtta ataaagttta
      121 taattcagat aaaaaaatta ttaatttctt aagggaggaa atatcgtgaa tatagtaatt
      181 agccttatcg gtggacttgg actttttctt tacggaatga gtttaatggg agaaggttta
      241 caaaaatcag caggagacaa attaaaaaaa attattgaac tcttaacaag taatgttgtt
      301 atgggtgtac tggtaggtac agtcgttaca ggtattatac aaagttcaag tgctactact
      361 gttatggttg taggatttgt aaatgcaggt ataatgaatc taagtcaagc tattggtgta
      421 ataatggggg caaatatagg tactacagtt actgctcaat tagtttcatt taatcttgaa
      481 ggaattgcac caattgcttt aggtataggt attttattct atttatttac atcaaatcaa
      541 aaaacaaagc atttatctga gatacttata ggttttggta tattatttac aggaatggag
      601 tttatgaaag atgcagtagc tccacttgct gaatacaaag cattcactga tgcactttta
      661 tattttagta aaaatcctgt attaggtata ttggcaggat ttgccataac tggtattgtt
      721 caaagttcaa gtgcatctat gggtatgtta atagcactag cttctcaagg aatacttcct
      781 ctatcatctg ctttacctat tctttatgga gataatatag gtacttgtgt tacttcactt
      841 ttatcaagtg ttggtgcaag tagaaatgct cgacgtgcag ctgtaatgca tttaagtttt
      901 aatgtaattg gtacaataat atttatgctt gttttaaata aacctatatc agccatagtt
      961 actcattttg acccaactga tacagctaga caaatagcaa atgcacatac tttatttaat
     1021 cttacaaatg ttataatatt attaccattt tctaaataca tagttaaatt agcaaataga
     1081 cttataccta ttaaagaaac tgaatcagaa atagtaaata atactaagta cttagatgaa
     1141 aggatgttta gcactccatc tatagcactt ggtaatactg tacaagaagt tgtaagaatg
     1201 ggtcataaag ctacaaactc tttggaacat tcaattgcag gatttttaaa taagagcaat
     1261 gaagatatta ataaagcttt tgagtcagaa aaagttgtca ataagttaca gaaagatata
     1321 ttgaactatt tgttaaaact ttctaaagaa cctcttagag atgatgaaca ctttagaaca
     1381 gatttgcttt ttaatactgt aaatgacatt gaaagagtct ctgaccatgc agaaaatata
     1441 gctgaattgg ccatgagtgt taaggaaatg aacattagtt tttctgatag tgcgataaga
     1501 gaaatatacg aaatatacaa taagacaatt actaatttta aggatgcctt aatagtttta
     1561 gatgttaaag attttgagtt agcaaataaa gttttagaag ttgaaaatga agtaaattat
     1621 ttagaaaaaa cttttagaaa ttcacatatg attagactaa ataatggaag ttgtacaatt
     1681 gatgctggtg tactttatct tgacttactt actaatctag aaagaatttc tgaccactca
     1741 acaaatatag taaaacaagt actaaaactt aaacaaaaaa tatagtgatt atttttatat
     1801 ataatcttaa tcaatgagaa gtaagaagct atagataatg cttatatcat ttatggtttc
     1861 ttatttttta tgtaatactc aaatttttat agtattctct tattattaaa caatttctgc
     1921 ctagaatatt ccatatatat atgacttctt tcataaaact tgaactgccc ataactaaag
     1981 tcacaagtat acataactat tttttaatca attataacca atatttgttt tatttatctt
     2041 cattttaatt cttcattcaa taatgtaata agattatttt ttatttggat actattatat
     2101 catctaaata tgttattata tatttggata ttttcatatt aataggaggg attctacaat
     2161 gataaattat atggtagaaa ttatatatag cgaaaaaata agcgaagtag aaaacatgtt
     2221 gaaaattgaa aatatacaat atgaatttac ttctcgtgat ggctttatat tttttggttt
     2281 ttatgatatg acagacgcat atagatttga gactttatgt tcagatgaaa aaattcgatt
     2341 taaaagaata taatagataa aaaagtacat atttctaaac tatttgtttt tcaaatttag
     2401 gttgtgtttt aatgtagtgt tgatattata aacaatttta ataataaaaa agtagggaca
     2461 ttatattaat atgctcctac tttttactca tacttattaa tattatttat caaaa
//
LOCUS       DAJMZY010000205         2462 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.210, whole genome shotgun sequence.
ACCESSION   DAJMZY010000205 DAJMZY010000000
VERSION     DAJMZY010000205.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2462)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2462)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2462
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.210"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            complement(563..1114)
                     /locus_tag="OE968_003723"
     CDS             complement(563..1114)
                     /locus_tag="OE968_003723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCP7220948.1"
                     /translation="MSINTVIAKNLNRLRNERNLSLGQLAELSGVSKVMLSQIEKGDS
                     NPTVNTIWKIASGLNVPYTAILEQPQNETFIVSKTDIDVQVSENKDYRLYCYYPNTPT
                     RNFELFQMELEEGHSYTSVGHSEKSQEYIMIIEGQLKLEVNDSIYQLRENDSICFSAE
                     SIHTYHNQGEKTLKAVIINYYPV"
     gene            1305..2267
                     /locus_tag="OE968_003724"
     CDS             1305..2267
                     /locus_tag="OE968_003724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase family protein"
                     /protein_id="HCP7220949.1"
                     /translation="MRVLNNVTEAIGNTHMLHLSKIADEFGVQGNIYAKMEYLNPGFS
                     KKDRVALQMITEAENAGLLVPGQAVVELTSGNTGTGLAIACACKGYKFIACMSKGNSM
                     ERARMMKALGAEVVLVDQMPNSVHGQVSGEDLALVEIEAQKIAKERNAFRADQFNLEA
                     CNHAHEKYTAEEMWEQLDGNIDVFVDFLGSGSTFAGCSKTLKKHNSSIKCYVVEPETA
                     AIYSGKEITDQGHKIQGGGYSMDLPLVDKKLIDGYIQVTDEEATDVARKLAKLEGVFA
                     GFSSGANVCAAIKLLKSSEKGKNIVLTLNDSGLKYLSTDLYEEL"
BASE COUNT          944 a          263 c          411 g          844 t
ORIGIN      
        1 ctattcaatt atttaacctc ttaaattata tttagatata ggagtcttat gataaaagta
       61 agcttatgtg ttatttgtag taaatataaa gtgcatatag tgataaaaca aaagtttcat
      121 ataaatgaag aaaaaaatat aaaataattt atttaactac ttaaaaataa actaaaaggg
      181 ataataaaat agcttttagt ttatggtaat agaggtattt aaaaagagtg cataagcact
      241 ccaattgtga gaaatacata cacaaatcat tattacaaca atgaaaaatg tacatataag
      301 agacgttttg tatttgtttt aagtgataat attttaatac taactaaata attatcacaa
      361 tggtaaaaaa gaaaaaggag tattttgtac tccatttgtc aaaaatataa aacttttata
      421 taagcttatt ataacataat tgataaaagt gtaaagatat ataatgaatt tataaagaaa
      481 aataaaataa aaaagataaa tcctaatcaa aggatttatc tttttgtata gaaaataatt
      541 attctattat taaatggcat ggctaaactg gataataatt tattattact gctttcaatg
      601 ttttttctcc ttgattatgg tatgtatgaa ttgattcagc tgaaaaacaa atagagtcat
      661 tttctctaag ttgataaata gagtcattta cttctaattt taattgacct tctataatca
      721 taatatattc ctgtgatttt tcagaatgac caacagatgt ataactatga ccttcttcta
      781 attccatttg aaataattcg aagtttctag ttggtgtatt gggataataa caataaagac
      841 gataatcttt attttctgaa acttgtacat ctatatcagt ttttgataca ataaaagttt
      901 cattttgagg ttgttccagt attgcagtat atggaacatt tagtccactt gcaattttcc
      961 aaattgtgtt tactgttggg tttgagtctc ccttttcaat ttgagaaagc attactttac
     1021 ttacgccaga taattcagca agttgaccta gacttaagtt acgttcatta cgtaatctat
     1081 ttaaattttt agcaataaca gtattaatac tcatagtagc tccttaaaat gtaaattatt
     1141 gacaaatata atttacgaat gtataattta tttaacatta tttataattt acaaatgtat
     1201 aatataatga acgttaaata cactgtacat ccgtaatata aattatactg cataaagagt
     1261 tgtttttcaa cggatgatag ttgagagatt aagggggaat tgtaatgcgt gtacttaata
     1321 atgttacaga ggctataggc aatactcata tgttacattt atccaaaata gcagatgaat
     1381 ttggagttca aggtaatatt tatgcaaaga tggaatactt aaatccggga tttagtaaaa
     1441 aggaccgtgt agcattacaa atgattaccg aagcagaaaa tgcaggttta ttagttccag
     1501 gtcaagcagt tgtggaatta acaagtggta atactggaac aggactagca atagcttgtg
     1561 catgtaaagg atataaattt atagcgtgta tgtcaaaagg aaattctatg gaaagagcaa
     1621 gaatgatgaa agctttaggt gctgaagtag ttcttgtaga ccaaatgcct aattcagttc
     1681 atggacaggt atctggtgaa gatttggcac ttgtagaaat tgaggctcaa aaaatagcaa
     1741 aagaaagaaa tgcatttaga gcagaccaat ttaatttaga agcttgtaat catgcacatg
     1801 aaaagtatac agcagaagaa atgtgggaac aattggatgg aaatattgat gtatttgtag
     1861 attttcttgg aagtggtagt acttttgcag gatgttcaaa aacacttaaa aaacataatt
     1921 cttctatcaa atgttatgtt gttgaacctg aaacagcagc aatttattca ggtaaagaaa
     1981 taactgacca agggcataaa atacaaggtg gaggatattc tatggatttg ccattagtag
     2041 acaagaaact tattgatggt tatattcaag ttacagacga ggaggcaact gatgtagcaa
     2101 gaaaattagc taaattagaa ggtgtatttg caggattttc ttcaggggca aatgtatgtg
     2161 cagcaattaa gttgttaaag agcagtgaaa aaggaaaaaa tatagtttta actcttaatg
     2221 atagtggttt aaaatattta agtactgatt tatatgaaga attgtaataa tagcacaata
     2281 gttatgcaat gttttttaaa ttaagtatat agatttaaat tataaaaagt atctcaatgt
     2341 aaattttgaa agttataaag gagatacttt tttattttgt aaatatggag tatcctactt
     2401 ataagtatta agctatatag atattgatga ttagctatgc aataaaaaag agtatgtgtt
     2461 tt
//
LOCUS       DAJMZY010000206         2405 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.211, whole genome shotgun sequence.
ACCESSION   DAJMZY010000206 DAJMZY010000000
VERSION     DAJMZY010000206.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2405)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2405)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2405
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.211"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            50..1675
                     /locus_tag="OE968_003725"
     CDS             50..1675
                     /locus_tag="OE968_003725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCP7220950.1"
                     /translation="MLQVTGVGLRFGDKELFKDVNLKFTKGNCYGIIGANGAGKSTFL
                     KILSGEIEPNTGSISITDKERMSVLKQDHFEYEEETVLNVVIRGHERLWNIMKEKDAL
                     YMKEDFNEEDGIKAAELEGEFAELDGWDAETNAEKILMGLGITKDMHYKQMKELVGGE
                     KVKVLLAQSLFGKPEILLMDEPTNHLDFKSINWLNNFIMDLEESIVIIVSHDRHFLNQ
                     ICTNIVDVDFGKIQMYVGNYDFWYESSQLALQLAKDQNKKTEEKIAQLKEFIARFSSN
                     ASKAKQATSRKKQLEKLEVEDIQPSRRRYPYVGFTPAREIGNEVLEVHNLTKTIDGVK
                     VLDNVSFRLDRDDKVVFMGDEIATTALFNIVMGELEPDSGEYKWGVTTSQDYLPKNHN
                     KFFDGVEYSLVDWLRQFSEEKSESFIRGFLGRMLFSGEEALKEAQVISGGEKVRCMLS
                     KLMLSNANVLVLDDPTNHLDLESITSVNKGLEKFPGVLLFTSHDHEFISTIANRIIEI
                     TPNGIMDRKMDFDEYLESKEIQDQLAKMYGKDK"
     gene            1874..2350
                     /locus_tag="OE968_003726"
     CDS             1874..2350
                     /locus_tag="OE968_003726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220951.1"
                     /translation="MVKKRLVAVVISLAMISVGNFSYAHSGGHNSSGDHHNKNKSELT
                     RYYCGGHSAHQHNKGFCPYASTKENSGVTISSVHNEKNHKNYFAEKGYNKGYEDGCKG
                     LYNLSVTEAKSDNLYEKEILKSSYEKGYLIGYNEYKAKKVDDVMKKMLDIPMLASI"
BASE COUNT          961 a          243 c          467 g          734 t
ORIGIN      
        1 agttttatga taaaataaat tatgagcaaa aagaaaggaa aatatattaa tgttacaagt
       61 tacaggtgtt ggacttagat ttggtgataa ggaactattt aaagatgtta acttaaaatt
      121 cactaaaggt aattgctatg gaataatagg agctaatggt gcgggaaaat ctactttttt
      181 aaaaatatta tcaggagaaa tagagcctaa tacaggtagt atatctataa ctgataaaga
      241 aagaatgtca gttttaaaac aggaccactt tgaatatgaa gaagaaactg ttttaaatgt
      301 tgttataaga ggtcatgaga gactttggaa cataatgaaa gaaaaagatg cattgtatat
      361 gaaggaagac tttaatgaag aagatgggat aaaagctgcc gaacttgaag gtgagtttgc
      421 agagcttgac ggatgggatg cagaaactaa tgctgagaaa atacttatgg gtcttggcat
      481 aacgaaagat atgcattaca aacaaatgaa ggaactagtt ggtggggaaa aggttaaggt
      541 attgttagca caatcacttt ttggtaagcc tgaaatacta ttaatggacg aacctacaaa
      601 ccacttagat tttaaatcaa taaactggtt aaataatttt ataatggatt tagaagaatc
      661 tatagttata atagtatcac atgatagaca tttcctaaat caaatatgta ctaatatagt
      721 tgacgtagat tttggtaaaa tacaaatgta cgttggaaac tatgatttct ggtatgagtc
      781 aagtcaattg gctttacaac tggctaagga ccaaaataaa aagactgaag aaaagatagc
      841 tcaattaaag gaatttatag ctagatttag ttctaatgct tcaaaggcta aacaagcaac
      901 atcaagaaag aaacagttag agaaattaga agttgaagat atacaaccat caagaagaag
      961 atatccatat gtaggattta cacctgcaag agaaattggg aatgaagttt tagaagtaca
     1021 caatttaact aaaactatag atggggttaa ggttcttgat aatgtgtcat ttagattgga
     1081 tagagatgat aaagtagtat ttatgggaga tgaaatagct actactgcac ttttcaacat
     1141 agttatggga gaacttgaac cagacagtgg agagtataaa tggggagtaa ctacttctca
     1201 agattatctt ccaaaaaatc ataataagtt ttttgacgga gtagaatatt ctttggttga
     1261 ctggcttaga cagttctctg aagaaaaaag tgaaagtttt ataagaggat ttttaggtag
     1321 aatgttattc tcaggtgaag aagcattaaa agaagctcaa gttatatctg gaggagaaaa
     1381 ggttagatgt atgcttagta agctaatgct ttcaaatgca aatgtacttg tattagatga
     1441 ccctaccaac cacttagacc tagaaagtat aacttctgta aataaaggac ttgaaaagtt
     1501 cccaggagtg cttttattta cttctcatga ccatgaattt atatctacta tagcaaatag
     1561 aattatagag ataactccaa atggaataat ggatagaaaa atggactttg atgagtattt
     1621 agaaagtaaa gagatacaag accaattagc taaaatgtat ggaaaagata aataattatt
     1681 agtataaaac cttttaatat ttgagacatg ctatgcatga gtgtgtaaat ttttaatcaa
     1741 atattaggag gttttttatg ttgtttaaac atgtttatta gcagaataga gtaatatttt
     1801 gtatattaag aatttaaata taatatagta gatgatataa taaaaatata taacattttg
     1861 gggggaatag attatggtta agaaaaggtt agtagctgta gtaattagtt tagctatgat
     1921 tagtgtaggg aatttttcat atgctcactc aggagggcat aattcatcag gagatcatca
     1981 taataaaaat aaatcagagt taacacgtta ttattgtgga ggacattcag cacatcaaca
     2041 caataaaggt ttttgtcctt atgctagtac aaaagaaaat tctggagtaa caatatcttc
     2101 agtacataac gaaaaaaatc ataaaaacta ttttgcagaa aaagggtata ataaaggtta
     2161 tgaagatggg tgtaaagggc tttataattt aagtgtcaca gaagccaaat ctgataattt
     2221 atatgaaaaa gagattttaa aaagttcata tgaaaaagga tatttaattg gatacaatga
     2281 atataaagca aaaaaagtag atgatgtaat gaagaagatg ttagatattc caatgttagc
     2341 aagtatataa taatatagta tttaaaaaga tattttctat aagggaatat cttttttatt
     2401 gtaaa
//
LOCUS       DAJMZY010000207         2333 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.212, whole genome shotgun sequence.
ACCESSION   DAJMZY010000207 DAJMZY010000000
VERSION     DAJMZY010000207.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2333)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2333)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2333
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.212"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            <1..1746
                     /locus_tag="OE968_003727"
     CDS             <1..1746
                     /locus_tag="OE968_003727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HCP7220952.1"
                     /translation="FSLYHSIEHIKIISHTGTIRSETQKVVKQELNNERNDDLIKRLD
                     NILIKLRTGNGENGFQRCDNKEFQQKLNQMDSMWESMKKEIIKVRNGASGDKLYKLSE
                     EYSVLSNQIVFISEKHSNAKLYSFATALFIYLIFSTISLLIWEYYNKKRFKRIFYTDN
                     LTKIKNQVAFENRAIEILHNASNKEYVLLNIDIDNFKYINDTHGYEYGDKVLIIVAAA
                     LSKTFNIKETCARIGSDNFVILAKYRDSLLEDIREMLTNAIISELDMNVTQTISYCIG
                     AYLVEIDNLGYKSINSIMDKANIAHKVSKTRGISSTVWYNENLLKQLQMENSIYNYMY
                     KAIENEEFHMYLQPKFQISSLNVVSAEALVRWFSPELGFLSPDEFIPLFEKSGFIIEL
                     DFYMLKKACSFVRKTFMKKNQYTYPIAVNFSRVTIYQNSFYQRFLDTVKEYEIPFKYI
                     EIEVTESAFNEISQPVISILEELKKLGFLISMDDFGSGYSSLSLLCSLSINGLKLDKS
                     LLKETFNREKVYSIIQCIIEMSHRIGMSVVCEGIETKKDLEFLNTVKCDVGQGFYFSK
                     PIEEKEFFNKYVTKK"
     gene            complement(1834..>2333)
                     /locus_tag="OE968_003728"
     CDS             complement(1834..>2333)
                     /locus_tag="OE968_003728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220953.1"
                     /translation="IAKIPFVKKDNSNFNYTNYYMEFEDIPEYYEVNFNNYLYIITRF
                     SFIPDGTEIFFTWEEIHCWDEKVATEKTFINGETLVDSYNFPNNEVKDYIQKRESLYI
                     ETKKYYEEKGLKIERHALGSEDGEYVELTNDSILYLLDIEAVEIREQSKNIEEFLYKY
                     KKRFK"
BASE COUNT          868 a          266 c          337 g          862 t
ORIGIN      
        1 ttttctctat atcacagtat agagcatatt aaaattataa gtcacactgg tactattcgc
       61 agtgaaactc aaaaggttgt taagcaagaa ttgaataatg aaagaaatga tgacttgata
      121 aaacgactgg ataatattct gataaagcta agaacaggta atggagaaaa tggatttcaa
      181 agatgtgata ataaagaatt tcaacaaaaa ctaaatcaaa tggattctat gtgggaatct
      241 atgaagaaag aaattataaa agttagaaat ggtgcttcag gtgataaatt atataaattg
      301 agtgaagagt attctgtgtt gtctaatcaa attgttttta tatctgaaaa acactctaat
      361 gcaaaattgt attcttttgc tactgcacta tttatttatc ttatattctc aacaataagt
      421 cttttaattt gggaatatta taataaaaaa aggtttaaaa gaatatttta tactgataat
      481 ttaacaaaaa taaaaaatca ggttgcattt gaaaacagag cgattgaaat tttgcacaat
      541 gcatctaaca aagagtatgt actgctaaat attgatattg acaattttaa atatattaat
      601 gatacacatg gatatgaata tggagataaa gttctaataa tagttgcagc tgcactttct
      661 aaaactttta atatcaaaga aacttgtgca agaattggtt cagataattt tgtaatactt
      721 gcaaaatata gagattctct tttagaggat attcgggaaa tgctaactaa tgctataatc
      781 tctgaattag atatgaatgt aactcaaact atatcttatt gtataggagc gtacttagtt
      841 gaaattgata atttaggtta taaatccatc aattctataa tggataaggc aaatattgca
      901 cacaaggtaa gtaaaacaag aggaatttcc tccacagtat ggtataatga aaatctgtta
      961 aaacagttac aaatggaaaa tagtatttat aattatatgt ataaagcgat agaaaatgaa
     1021 gaatttcata tgtatttgca acctaaattt caaatatctt ctttaaatgt tgtaagcgca
     1081 gaagctcttg taagatggtt ttctccagaa cttggttttt tatcaccaga tgaatttatt
     1141 ccattgtttg aaaaaagtgg atttattatt gaattggact tttatatgtt aaaaaaagcg
     1201 tgttcatttg taagaaaaac gtttatgaaa aaaaatcaat atacatatcc gattgcagtt
     1261 aatttttcaa gggttactat ttaccaaaat agtttttatc aaaggttttt agatactgtt
     1321 aaagaatatg aaattccttt taagtatata gagatagagg taactgaaag tgcttttaat
     1381 gaaatatctc aaccagttat ttcaatttta gaggaactta aaaagttagg atttttaatt
     1441 tcaatggatg attttggttc aggatactct tcattaagtc ttttatgttc tctatctatt
     1501 aatggattga agttagataa aagcttactt aaagaaacct ttaaccggga gaaagtatat
     1561 agtattattc aatgtattat tgaaatgtca catcgtatag gcatgtctgt tgtatgtgaa
     1621 ggtattgaaa ctaaaaaaga cttggaattt ttaaatacag ttaaatgtga tgtaggacaa
     1681 gggttttatt tttctaaacc gatagaagaa aaagaatttt ttaacaaata tgtaactaaa
     1741 aaataatata attattttta tcagtctata cattgagtca ttttatatct cgttaaatga
     1801 ctcaatgtac tgttatgtat tttaaaatat aaattattta aaacgttttt tatacttata
     1861 tagaaattct tctatatttt ttgattgttc tcttatttca actgcttcta tatctagtaa
     1921 ataaagtata gaatcatttg taagttcaac atattcacca tcttctgaac cgagtgcatg
     1981 tctctcaatt tttaatcctt tttcttcata atattttttt gtttctatat ataatgattc
     2041 tcgcttttgt atgtagtctt tcacttcatt atttggaaag ttatatgaat ccactaatgt
     2101 ttcgccattt ataaaagttt tctcggtagc aactttttca tcccaacaat ggatttcttc
     2161 ccaagtaaaa aatatctcag ttccatctgg aatgaatgaa aacctggtaa taatatataa
     2221 ataattattg aaatttactt cataatattc aggaatatct tcaaattcca tatagtaatt
     2281 tgtataatta aaattactat tatctttttt tacaaagggt atttttgcaa taa
//
LOCUS       DAJMZY010000208         2269 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.213, whole genome shotgun sequence.
ACCESSION   DAJMZY010000208 DAJMZY010000000
VERSION     DAJMZY010000208.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2269)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2269)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2269
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.213"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     misc_binding    38..269
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            377..1858
                     /locus_tag="OE968_003729"
     CDS             377..1858
                     /locus_tag="OE968_003729"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HCP7220954.1"
                     /translation="MYYSSTRGTEEKVTASQAIIKGISNDGGLYVPSEFPNVKNELIN
                     LVNLTYSQIAFFVLSKFLCDFTEDEIKNCIENAYDEKFDCSSIAPLNKVNDTYFLELY
                     HGPTLAFKDMALTIMPHLLKTSIKKDNLEKDVVILTATSGDTGKAALEGFKDIDKIKI
                     IVFFPEDGVSPVQKLQMKTQTGKNTYVVGIKGNFDDAQSGVKKIFSDKEFNQKLLDNN
                     YILSSANSINIGRLLPQVAYYFYSYMKLVSNSDINLNDKINFVVPTGNFGNILAGYYA
                     KQMGLPINKLICASNDNNVLYDFFKTGVYDKNRTLKLTTSPSMDILISSNLERLLFEI
                     SNRNTDIVNKLLSDLSDKGVYKISDDMEKNLASFYGEYSNEEEVKSTINNVFKNYNYL
                     IDTHTAVAYNCYEKYKKETSDNTKTVIVSTASPFKFSEDVLKSIDCDFKDLDDFAIID
                     RLSSISKIDIPKPIKNLKNAEILHKDIYEKDELKLAIKKFLKV"
     gene            1868..>2269
                     /locus_tag="OE968_003730"
     CDS             1868..>2269
                     /locus_tag="OE968_003730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HCP7220955.1"
                     /translation="MLEIIVPATSANIGPGFDCLGIALNIYNKFYVEEIESGLEIEGC
                     EDAYKNENNLVYTSMKYFFDRVKPEKIPAGIKIKIQSEVPICRGLGSSASCIVAGVIA
                     ANALSGANLDKNQLLNIASEIEGHPDNVAPAI"
BASE COUNT          884 a          263 c          361 g          761 t
ORIGIN      
        1 ttttataaac tagaataatt aataatatta agaatattga aaggcattga ttaggaagag
       61 taaatctgaa tcgattacca gagaaggaaa ctactagctg aaatgtttcc ctaattagaa
      121 ggattgaaaa ctacctagga gcttctatcc gaagttatct taatgatttt agtaggaata
      181 gacgttttta ttacttgcgt taaagtatca agtggatttt ttaaaatcaa tttgggtgga
      241 accgcgggaa acagattctc gtcccttttt tagggatgag ggtctttttt tattacctaa
      301 attcagtttt taaaatattc tgtatctaat ttaattagct aattaaaaat ttaaaatata
      361 tggaggatta taaaaaatgt attattcaag tacgagaggc accgaagaaa aagtaactgc
      421 atcacaagca ataataaaag gaatatcaaa tgatggtggt ctttatgttc caagtgaatt
      481 tcccaatgta aaaaatgaac ttataaattt agtaaattta acgtattctc agatagcatt
      541 ttttgtactt agtaaatttt tatgtgattt tactgaagat gaaattaaaa attgtataga
      601 aaatgcatat gatgaaaagt ttgattgtag tagtatagct ccattaaata aagtaaatga
      661 tacttatttc ttagaactat atcacggtcc aactttagca tttaaagata tggcacttac
      721 tataatgcct catcttctta aaacatctat aaagaaagat aatttagaga aagatgttgt
      781 gattcttact gctacatctg gagatacagg taaagctgca cttgagggat ttaaagatat
      841 agataaaata aagataattg tattcttccc agaagatggt gtaagcccag tacaaaaact
      901 tcaaatgaaa actcaaactg gaaaaaatac atatgtagtt ggtataaaag gaaattttga
      961 tgatgcacaa tcaggtgtaa agaagatttt ttctgataaa gaatttaatc aaaaactatt
     1021 ggataataat tatatattat cttctgcaaa ttcaattaat ataggaagac ttcttccaca
     1081 agttgcatac tatttttatt catatatgaa attagttagc aatagtgata taaatttaaa
     1141 tgataaaata aattttgttg tcccaactgg taattttggt aatattctag ctggatatta
     1201 tgccaaacaa atgggtcttc caataaacaa attaatatgt gcatcaaatg ataataatgt
     1261 tctttatgat ttctttaaaa ctggtgtata tgataaaaat agaacattga aattaactac
     1321 ttctccttct atggatatat taatttcaag taatttagaa cgattactgt ttgaaatatc
     1381 aaatagaaat actgatattg taaataagct tttatcagac cttagtgata aaggagtcta
     1441 caaaataagt gatgatatgg aaaaaaattt agcctcattc tatggagaat attcaaatga
     1501 agaagaagtt aaaagcacga taaacaatgt gtttaaaaat tataattatt tgatagatac
     1561 tcatactgct gttgcataca attgttatga aaaatataaa aaagaaactt ctgataacac
     1621 aaaaactgtt attgtaagta ctgcaagtcc attcaagttt tctgaagatg ttctaaagtc
     1681 tatagattgt gattttaaag accttgatga ctttgctata attgatagat tatcaagtat
     1741 ttctaaaata gatattccaa aacctattaa aaatcttaaa aatgcagaaa tactacataa
     1801 agatatttat gaaaaagatg aattaaaact agctataaaa aaattcttaa aggtataggt
     1861 gattattatg ttagagatta tagttcctgc aacaagtgct aatataggtc caggatttga
     1921 ttgtcttgga attgcgttaa atatatacaa taaattttat gttgaagaaa ttgaaagtgg
     1981 tcttgaaata gaaggttgtg aagatgctta caaaaacgaa aacaacttag tttatacatc
     2041 tatgaagtac ttttttgata gagttaaacc agaaaaaata cctgctggta tcaaaataaa
     2101 aatccaaagt gaagtaccta tatgtagagg tcttggcagt agtgcctctt gtatagtagc
     2161 tggagttata gctgcaaatg ctctatcagg tgctaattta gataaaaatc aattactaaa
     2221 tatagcttca gaaatagaag gtcacccaga taatgttgct cctgctatt
//
LOCUS       DAJMZY010000209         2258 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.214, whole genome shotgun sequence.
ACCESSION   DAJMZY010000209 DAJMZY010000000
VERSION     DAJMZY010000209.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2258)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2258)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2258
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.214"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            complement(73..681)
                     /locus_tag="OE968_003731"
     CDS             complement(73..681)
                     /locus_tag="OE968_003731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HCP7220956.1"
                     /translation="MEKDFFRKNGIDLAKSILGKYLIRKYENKVIVTKIIETEAYMGV
                     NDKGAHVYGNKKTDRTKPLYLDGGHIYVYLIYGMYNCLNLSANIENVPECVLIRGVEP
                     ITSLDEISMNRYNKAYTELSKYQVKNITNGPGKLCKALKIDRSLNSKSIMGEELYISD
                     FYYDDKGKKVFSKDELDIKTSKRINIDYAEEAKDFLWRFYIE"
     gene            complement(790..>2258)
                     /locus_tag="OE968_003732"
     CDS             complement(790..>2258)
                     /locus_tag="OE968_003732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="PAS domain-containing sensor histidine kinase"
                     /protein_id="HCP7220957.1"
                     /translation="SFKCVSSDLVDMTLEQYFETFNIDFFDNREFKRLNLTQEKKAEI
                     VSYNDTANCIVNFVMSDSEGEEHVEEVRVGDYWSDNKLFKLLTFRDITKEINILRTVN
                     EQKIIYEKLLDVIPEAIFLEDLSTSRVLYTNRAFRELFGISSDVLGVTTQKYRNILVK
                     KYINNLNIGEREKSIHIVNENNHIKEVKMISRTLYFGQKRSRVRIIKDLSVQRESERL
                     KKALIKQRQYDQMKMEFYANISHELKTPLNNIYSSVQLIENLYKKGKIIDFQDILKEH
                     IKITKQNMFRLLRLIDNIINISQVKSDIYKIKAVNFDIIDITERIVTSISSYAKSKGI
                     DLIFDTDEETVMVGLDPESIERIILNILSNAIKFTLEGGEILVGIYKKDETVEIIIKD
                     TGVGIDKEKLNDIFNRFKQIENSGISNEFGSGIGLCLTKSLIEIQNGKIYIDSKVGEG
                     TNVKVIFPIKEVVEEVYDNSNYNDNIEKFEIEFFDIYK"
BASE COUNT          719 a          387 c          181 g          971 t
ORIGIN      
        1 attctataaa aaaataagat acatacctat aaaatacctt cctatagata catatcttac
       61 ctatataaaa acttattcta tataaaaacg ccataaaaaa tcttttgctt cttctgcata
      121 atctatattt atacgtttac tagtttttat atctaactca tctttactaa atactttttt
      181 tcctttatca tcataataaa aatcacttat atataattct tcacccatta tactcttact
      241 atttagactt ctatctattt ttaaagcttt gcaaagtttt cctggtccgt tagtaatatt
      301 ttttacttga tatttactca actcagtgta agctttgttg tatctattca tagatatctc
      361 atctaaagaa gttataggct ctacccctct tattaataca cactctggca cattttctat
      421 atttgcagat aaattcaagc aattatacat accataaatt aaataaacat atatatgtcc
      481 accatctaaa tataatggct tagttctatc tgtcttttta ttgccatata catgtgctcc
      541 tttatcattt acacccatgt atgcttctgt ctctatgatt ttggtaacaa ttactttatt
      601 ttcatatttc cttattagat atttacctaa tattgatttg gctaaatcaa ttccattttt
      661 tctaaaaaaa tccttttcca aaatttcacc tcataaaatt tatttaaaac gcatcaaata
      721 caactaaagt aataaataaa attaactctt attaatgtga tatatataaa caataaattt
      781 agacatttat tatttatata tatcaaaaaa ttctatctca aacttttcaa tattatcatt
      841 gtaatttgaa ttatcatata cttcttcaac aacctcttta attgggaata taacttttac
      901 attagttcct tctcctacct tactatctat gtaaatcttc ccattttgaa tttcaatcaa
      961 tgattttgta aggcataaac ctataccact tccaaattca tttgatatac cactgttttc
     1021 aatttgttta aatcgattaa atatatcatt taatttttct ttgtctatgc ccactccagt
     1081 atcttttata attatctcta ctgtttcgtc ttttttatat atacctacaa ggatttctcc
     1141 tccttctaaa gtaaatttta tagcatttga taatatattt agtattattc tttctatcga
     1201 ttctgggtca agccctacca taacagtttc ttcatctgta tcaaaaatta aatctattcc
     1261 tttagactta gcataactac taatagatgt aactattctt tctgttatgt caataatatc
     1321 aaaattaact gctttaatct tatatatgtc tgacttaact tgagaaatat ttattatatt
     1381 atctattaat ctcaataatc taaacatatt ttgtttagtt atttttatat gttcttttag
     1441 tatatcctga aaatcaatta tttttccttt tttataaagg ttttcaataa gttgaactga
     1501 actatatata ttatttaaag gtgtcttaag ttcatgagat atattagcat aaaactccat
     1561 cttcatttgg tcatactgtc tttgttttat taatgctttt ttaagtcttt cagactctct
     1621 ttgcacactt aaatctttaa taattctcac tctacttctt ttctgtccaa agtataatgt
     1681 tcttgatatc atttttactt ctttaatgtg attattttca tttactatat ggatactctt
     1741 ctctctttct cctatattta aattgtttat gtattttttt actaatatat ttctatattt
     1801 ttgtgttgta actcctaata catcactaga aattccgaac aactctctaa aggctctatt
     1861 tgtatatagt actcttgatg tacttaaatc ctcaagaaaa atagcctctg gtataacatc
     1921 cagtaatttt tcatatatta ttttttgttc atttactgtt ctaagaatat ttatctcttt
     1981 agttatatct ctaaatgtaa gcaatttaaa gagtttatta tctgaccaat agtctccaac
     2041 tctaacttct tcaacatgct cttcaccttc tgagtcagac atcacaaaat taactataca
     2101 gtttgctgtg tcattgtaac ttactatttc agctttcttt tcttgtgtta gatttaatct
     2161 tttaaattcc ctattgtcaa agaaatctat gttaaaagtt tcaaaatatt gttctaatgt
     2221 catatcgact aaatcacttg aaacacattt aaaactct
//
LOCUS       DAJMZY010000210         2210 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.215, whole genome shotgun sequence.
ACCESSION   DAJMZY010000210 DAJMZY010000000
VERSION     DAJMZY010000210.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2210)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2210)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2210
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.215"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            complement(8..184)
                     /locus_tag="OE968_003733"
     CDS             complement(8..184)
                     /locus_tag="OE968_003733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220958.1"
                     /translation="MFGNKMDKCTHVLTAYISSSYDYCNFLDTQLDDFILEYGENVVE
                     SCLHQVMVLVSKYN"
     regulatory      complement(239..336)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            562..945
                     /locus_tag="OE968_003734"
                     /pseudo
     CDS             562..945
                     /locus_tag="OE968_003734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431032.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
     regulatory      1299..1392
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            1475..1960
                     /locus_tag="OE968_003735"
     CDS             1475..1960
                     /locus_tag="OE968_003735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HCP7220959.1"
                     /translation="MISELMLKNFRKSSINFKTKIKLNLREKPDINSLKLKSIPEGKI
                     VKLKCVDGIWAEVESNYDKGWLLYKYLERLSNAKNNSNDTIKNRKKNYIGNIRTNGLS
                     LELRNDRTLESKVITTIPDGFKVEVCYSVGKWARVNINKNEKRYSGYVYNQYIEEHLS
                     L"
BASE COUNT          960 a          218 c          302 g          730 t
ORIGIN      
        1 tgtctatcta attatactta cttaccaata ccattacttg gtgtaaacaa gactctacta
       61 cattttctcc gtactctaat ataaaatcat ctaactgtgt atctaaaaaa ttacaataat
      121 catacgaact gctaatataa gcagtcaata catgtgtaca tttatccatt ttatttccaa
      181 acatataaat tattatcccc ctaaaaaact ttcataaaaa caaaaagaac actatctctt
      241 tggcaactgg ctgacataac tcataagata tttatataag tcttagtccc tatagctttg
      301 cgtcactaaa tttctctagt tttgccgatt tagttttatt ctacaactaa aataatacaa
      361 tagaattagt tattattcaa caggattgtt tgaaagttaa ataaatttat agatatgaac
      421 attattttac acttaaaaac agactaaaca cgtagagtac ctggtaaaaa ttaaatatag
      481 tttttgttct aaaaagctcc tattataatt taagctagat aaatttgaag aagtgacata
      541 aattgaaaga aggaatatat tatgctaaat aaaaaattac cagatacaga attaaaaatt
      601 atgaaatgca tatggcatac tggttataaa actgtaatat caaaagatgt tgcagatgaa
      661 atagaaaaaa catatggttg gaagcataca actacaatta tacttttagc tagattaacc
      721 aaaaaaggtt ttttaatatc atagagaatt gggaggcatg tacactatac agtattaata
      781 aaagagagag aatatctcaa aatagaggga aaaagagttt ttagaggttt acataacaat
      841 cctttatcag aattaatttc aaaattacat gatggagaag aaataactga agaaaaaata
      901 atagaaatag gaagttggat aaaaagctgg aaatataaag attaataaat aaaaggtagc
      961 taataatata agtgctacct tttttatgtg gataatattg gtgataagtt gtggaaaact
     1021 tatataaaaa ttgtggataa agtgttttgc tgacatttta ctgacaaaag ttaaaaaaat
     1081 aaatgttata tattgtaaaa tgttgaaaaa tagccatata tataaaatat aagtaacact
     1141 atagataaat tactgtcttt tatattgact ataaagaaca gtaattgaat aaatataaag
     1201 atattttttg attattatta attaaaaatt taatttatat ttaaataata taaaatttga
     1261 ggtaatatta ttttttaatt gttcaaatta tgttattatt cagatatagg caatattaga
     1321 taaatctaat gacgcaaaac tatagggact aaaatcttta tgtaataaag gtcatgtcag
     1381 ccagttgcca aaaagataat aattcttttt gttaaaagta tttttagagt tatatatttt
     1441 aataacttaa tatttggcaa gaggagggct taagatgata tctgaattaa tgttaaaaaa
     1501 ttttcgcaaa tctagcatca attttaagac taaaattaaa ttgaatttaa gagaaaaacc
     1561 agacataaat agtttgaaat taaaaagtat accagaaggt aaaattgtta agttaaagtg
     1621 tgtagatgga atatgggcag aagttgagag taattatgac aaaggttggt tactttataa
     1681 atatttagaa agattaagta atgctaaaaa caatagtaat gatacaataa aaaatagaaa
     1741 aaagaattac ataggaaata taagaacaaa tggattaagt ttagaactta gaaatgatag
     1801 aacattagaa tctaaagtta taactacaat ccctgatggt tttaaagttg aagtatgtta
     1861 tagcgttgga aaatgggcaa gagttaatat caataaaaat gaaaaacgat attctggata
     1921 tgtatataat caatacatag aagagcattt aagtttataa tacgatacta gcaagcttta
     1981 aatatattaa taaatcgcaa aaaagaatcc cattaatggg attctttttt gtagaaacat
     2041 tataacagaa ctaaagagaa taaattaact aatttatttt tattataaag taattataaa
     2101 tggtaaattt aattgaaagt agatttaact tatactttat acaccaagta tcataaatta
     2161 atactacttt gaaaaatctt aaaaaaagta aaagttatga taataaaaat
//
LOCUS       DAJMZY010000211         2205 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.216, whole genome shotgun sequence.
ACCESSION   DAJMZY010000211 DAJMZY010000000
VERSION     DAJMZY010000211.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2205)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2205)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2205
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.216"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            complement(137..1429)
                     /gene="brnQ"
                     /locus_tag="OE968_003736"
     CDS             complement(137..1429)
                     /gene="brnQ"
                     /locus_tag="OE968_003736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HCP7220960.1"
                     /translation="MGEKQINFKDVIVIGFALFAMFFGAGNLIFPPYLGVLSGSSWLI
                     AFIGFLFADGGLALLAVIAATKFNGDTSKMFSRAGKGLSIALGCAMVICIGPLLAIPR
                     TAATTYEMGILPTIGSGISPVIFSIVFFALVLVLTIRPSKVVDIVGSILTPALLIALA
                     VLIVKGIISPLGEIRDSSLIQNVFAEGITQGYQTMDALAASVFASIIIMSVIAKGYTG
                     EKEKMKATISAGVIAVIGMALVYGGLCYLGATVSQQYGQDVQQTALIVAITAALLGTT
                     GKILLAIIVALACLTTAIGLSSAAGQYFSTLTDGKLKYEHIVIVVCVFSAIISNFGVS
                     TIIQFSSPILSMVYPATITLVILALFSNKIKNDNVFKCAAYMALLVSVLTVATSFGVK
                     IPLVNSLPFASLGFNWIVPVVIAGIIGNFIPSKSSKTA"
BASE COUNT          731 a          360 c          250 g          864 t
ORIGIN      
        1 aataaatttt taaatttatc aaataggatt aataatgttc ttttatctac aataatttaa
       61 taattctttt aaatataaaa aggaattgcc tatataattt aaaggcaatt ccataattat
      121 caattagttt ttattattat gcagttttac tgcttttaga tggaataaag tttcctatta
      181 ttcctgctat tacaactgga actatccagt taaatcctaa tgaagcaaat ggtaagctat
      241 taactagagg aatttttaca ccaaaacttg ttgcaactgt taatacactt actaataatg
      301 ccatgtatgc agcacatttg aacacgttgt catttttaat tttattacta aataatgcta
      361 gtataactag agttatagtt gctggatata ccatacttag tataggagaa gagaattgta
      421 ttattgtact tactccaaag tttgatatga ttgcactaaa tacacaaact actataacta
      481 tatgctcata ctttaatttt ccatctgtaa gtgttgagaa atattgacca gctgctgaag
      541 aaagacctat agctgttgtt aaacatgcta atgcaactat aatagccaat aaaattttac
      601 ctgtagttcc aagtaaagct gctgttattg caactattaa agctgtttgt tgaacatctt
      661 gtccatattg ttgagacaca gttgctccaa gataacataa tccaccataa actaatgcca
      721 ttcctattac tgcaattaca cctgcactta ttgtggcttt catcttttct ttctcacctg
      781 tataaccttt agctattact gacatgatta taattgatgc aaatacacta gctgccaatg
      841 catccattgt ttgataacct tgagttatac cttctgcaaa tacattttgt attaaagaac
      901 tgtctcttat ttctcctaat ggagatatga tacctttaac tattaatact gctaaagcta
      961 taagtaaagc tggagttaat attgacccaa ctatatctac aacttttgat ggtcttattg
     1021 ttaaaaccaa tactagagca aagaatacta tagagaatat tactgggctt attccagaac
     1081 ctattgtagg taatataccc atttcataag ttgttgctgc tgttctaggt attgctaaaa
     1141 gtggccctat acagattacc attgcacatc ctaatgcaat acttaatcct ttgcctgctc
     1201 ttgagaacat cttcgatgtg tctccattga acttagttgc tgctataact gctaataatg
     1261 ccaaaccacc atctgcaaaa aggaatccta tgaaagctat tagccaacta cttccagata
     1321 aaactcctag atatggaggg aagattaagt tccctgcacc aaaaaacatt gcaaatagtg
     1381 caaatccaat tacaattaca tctttaaaat tgatttgttt ctcacccatt taaagcaccc
     1441 ccatttgaat tttactacct tttactaaaa aataagtcca atctcttcat taaatgaaaa
     1501 ccttttgacg agattttatt taattataca tttttgactt aaatttgtca attatgtttc
     1561 ataatttata aaatcttcac aatatttaat acaactttct taattaaaca aaatcaacct
     1621 gtatacttta aacacagttg gttttttgtt ttttctctaa tttttcttga taaaattaat
     1681 tattctgaat aattaaaata ttaagatttt ttagattatt cgatttgtta ttaagtgtat
     1741 tgctttatat actgtatata tcactctcct tttttacatt catataatct ttttaattca
     1801 atttaaattt taaatatttt gtgtttatta tataatctga aaaaaaagca gtcaatagca
     1861 tttttaattt ttttaatttt caaaattatg attcttaaaa aatcgttttc cttttgtcat
     1921 agcacctatt tacgttaatt cttgtagtat tttgtattta ttttgctaaa ttgacagtta
     1981 actttattcg ttttttattc tatttatgta gatttgcctc ttgtttttta gtcttaaaat
     2041 cattttttct gaaaattcct tattatgatt tatcaactta tttttcttca tatcaattac
     2101 tttctaactt ccaacttact taaactttgc agttgctagt attcacgttt acatacttat
     2161 ctgtcataat taactaaaaa ttcttaatat atctctcaat gaaaa
//
LOCUS       DAJMZY010000212         1986 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.217, whole genome shotgun sequence.
ACCESSION   DAJMZY010000212 DAJMZY010000000
VERSION     DAJMZY010000212.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1986)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1986)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1986
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.217"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            84..200
                     /gene="rrf"
                     /locus_tag="OE968_003737"
     rRNA            84..200
                     /gene="rrf"
                     /locus_tag="OE968_003737"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            207..281
                     /locus_tag="OE968_003738"
     tRNA            207..281
                     /locus_tag="OE968_003738"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:239..241,aa:Asn,seq:gtt)
     gene            286..360
                     /locus_tag="OE968_003739"
     tRNA            286..360
                     /locus_tag="OE968_003739"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:319..321,aa:Glu,seq:ttc)
     gene            366..441
                     /locus_tag="OE968_003740"
     tRNA            366..441
                     /locus_tag="OE968_003740"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:399..401,aa:Val,seq:tac)
     gene            447..523
                     /locus_tag="OE968_003741"
     tRNA            447..523
                     /locus_tag="OE968_003741"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:481..483,aa:Asp,seq:gtc)
     gene            534..608
                     /locus_tag="OE968_003742"
     tRNA            534..608
                     /locus_tag="OE968_003742"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:566..568,aa:Thr,seq:tgt)
     gene            623..707
                     /locus_tag="OE968_003743"
     tRNA            623..707
                     /locus_tag="OE968_003743"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:657..659,aa:Tyr,seq:gta)
     gene            717..790
                     /locus_tag="OE968_003744"
     tRNA            717..790
                     /locus_tag="OE968_003744"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:749..751,aa:Gly,seq:tcc)
     gene            801..877
                     /locus_tag="OE968_003745"
     tRNA            801..877
                     /locus_tag="OE968_003745"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:835..837,aa:Arg,seq:tct)
     gene            887..962
                     /locus_tag="OE968_003746"
     tRNA            887..962
                     /locus_tag="OE968_003746"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:920..922,aa:Gln,seq:ttg)
     gene            974..1049
                     /locus_tag="OE968_003747"
     tRNA            974..1049
                     /locus_tag="OE968_003747"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1007..1009,aa:Lys,seq:ttt)
     gene            1052..1140
                     /locus_tag="OE968_003748"
     tRNA            1052..1140
                     /locus_tag="OE968_003748"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1086..1088,aa:Ser,seq:tga)
     gene            1158..1248
                     /locus_tag="OE968_003749"
     tRNA            1158..1248
                     /locus_tag="OE968_003749"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1192..1194,aa:Ser,seq:gct)
     gene            1257..1333
                     /locus_tag="OE968_003750"
     tRNA            1257..1333
                     /locus_tag="OE968_003750"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1291..1293,aa:Pro,seq:tgg)
     gene            1419..1494
                     /locus_tag="OE968_003751"
     tRNA            1419..1494
                     /locus_tag="OE968_003751"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1452..1454,aa:Trp,seq:cca)
     gene            1555..1631
                     /locus_tag="OE968_003752"
     tRNA            1555..1631
                     /locus_tag="OE968_003752"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1589..1591,aa:Pro,seq:tgg)
     gene            1638..1714
                     /locus_tag="OE968_003753"
     tRNA            1638..1714
                     /locus_tag="OE968_003753"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1672..1674,aa:Ile,seq:gat)
     gene            1718..1793
                     /locus_tag="OE968_003754"
     tRNA            1718..1793
                     /locus_tag="OE968_003754"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1751..1753,aa:Phe,seq:gaa)
     gene            1801..1877
                     /locus_tag="OE968_003755"
     tRNA            1801..1877
                     /locus_tag="OE968_003755"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1835..1837,aa:Met,seq:cat)
BASE COUNT          517 a          452 c          531 g          486 t
ORIGIN      
        1 taactctaaa aaaaaataaa aaaagtattg acaaaaatag taaaaaatgt taatattata
       61 cttgtcctag caacaagaaa aaatgtggtt ataatagcgg aggagataca cctgtttcca
      121 ttccgaacac agaagttaag ttctctagcg ctgatggtac ttggtgggaa actgcctggg
      181 agagtaggac atagccacgt gaatgttcca aggtagctca acggtggagc aaccggctgt
      241 taaccggtag gctgtgggtt cgagccccac ccttggagcc attatggctc gttggtcaag
      301 aggttaagac accgcccttt cacggcggta acaggggttc aattccccta cgagtcacca
      361 tttgtgggat catagctcag ctgggagagc acctgcctta caagcagggg gtcacaggtt
      421 cgagccctgt tggtcccacc atttgcggcc tggtagttca gttggttaga atgccagcct
      481 gtcacgctgg aggtcgaggg ttcgagcccc ttccaggtcg ccaaaataaa aatgctggtg
      541 tggctcaacg gtagagcagc tgacttgtaa tcagcaggtt gtaggttcga ttcctatcac
      601 cagctccatg taaaactaat acggaggatt tcccgagcgg ccaaaggggg cagactgtaa
      661 atctgttgtc atcgacttcg gtggttcgaa tccaccatcc tccaccaatt aaatatgcgg
      721 gtgtagctca atggtagagt tctggccttc caagccagct gtgagggttc gatccccttc
      781 acccgctcca aagaaagcgt gggtgcatag ctcagctgga tagagcaacg cccttctaag
      841 gcgtgtgtcc ggggttcgaa tccctgtgcg ctcaccacat atatattggg gattagccaa
      901 gtcggtaagg cacatgactt tgactcatgt atgcgtaggt tcgagtcctg catccccagc
      961 caaataaaaa tatggtctat tagctcagtc ggtagagcac ctgactttta atcagggtgt
     1021 cccgcgttcg agtcgcggat agatcaccaa tggagaggtg tccgagtggt ttaaggagct
     1081 ggtcttgaaa accagtgact tcgaaagggg ccgtgggttc gaatcccacc ctctccgcca
     1141 aaaaaatgac tgaatttgga gaagtactca agtggctcaa gaggatcccc tgctaaggga
     1201 ttaggctggg taaccggtgc gagggttcga atccctcctt ctccgccatt caaaaacgag
     1261 gtgtagcgca gtttggtagc gcacatggtt tgggaccatg gggccggggg ttcgagtccc
     1321 ttcacctcga ccaacttaag cttttagttc agttggttag agtgcccaac tcatggctag
     1381 taattctagg gtttgagtcc atgaaggtta ttcttcatag gggtgtagct cagttggtag
     1441 agcgtcggtc tccaaaaccg tgcgccgggg gttcgagtcc ctccacccct gccaaataaa
     1501 aaggacttga aaaaagttgg attttagagt agtataagat agtaaataag atttcgaggt
     1561 gtagcgcagt ttggtagcgc acatggtttg ggaccatggg gccgggggtt cgagtccctt
     1621 cacctcgacc aagaaaaggg cctatagctc aggtggttag agcgcacgcc tgataagcgt
     1681 gaggtcgctg gttcgagtcc agctaggccc accatttgcc cagatagctc agtcggtaga
     1741 gcaggggact gaaaatcccc gtgtcggtgg ttcgattccg cctctgggca ccaggaatac
     1801 ggcggtatag cttagttggc tagagcgttc ggttcatacc cgaaaggtca taggttcgac
     1861 tcctattacc gctaccatct aactatatca ataaagaact ttgaaaatta aacagtaggt
     1921 taatttataa acaagaaaca aaccataaag ccagatattt tgataacaat agtatctgag
     1981 cctgat
//
LOCUS       DAJMZY010000213         1971 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.218, whole genome shotgun sequence.
ACCESSION   DAJMZY010000213 DAJMZY010000000
VERSION     DAJMZY010000213.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1971)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1971)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1971
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.218"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            complement(86..1174)
                     /locus_tag="OE968_003756"
     CDS             complement(86..1174)
                     /locus_tag="OE968_003756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220961.1"
                     /translation="MSDKVNMKNIICIAGAYLATAIGSGFATGQEILQFFASQGYMGL
                     IGALISMVLFSFLGAEVITRGRELKLKEPTRIYTFYCGKILGKFYEWFSPIFLFGILI
                     VMISGAGSTLTEYYGINPYLGRVLMAVATLITVSMGLEKLVSILGRIGPVIAVFTIAV
                     GLISLFKHFDGLSMVGEAMKNIEVTKASESPIVSGVIYNTLNIIVMIVFLTGMGASIE
                     SKKDAFWGGLLGGIVFMTAGIVMYLAMISDIGNLYMKEIPSLYLADNISPIVGVCFSV
                     ALILGIYTTAVPLLWSVTNRIVEDEHPKFKLVTTVIAILACIGGFLPFGKLVNILYPY
                     TGYMGLLILVCMVYKAITCRKKSTQSQE"
     gene            complement(1459..>1971)
                     /locus_tag="OE968_003757"
     CDS             complement(1459..>1971)
                     /locus_tag="OE968_003757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding response regulator"
                     /protein_id="HCP7220962.1"
                     /translation="GLEVIEKTSHLSKKINFVVITAFNYFEYAQKALRLNVKDILLKP
                     LDMKEFTKSVEKIIGYQYTNNDLLNEILEYINLNYSNDLKLNDCARLFLTNPSNISRI
                     FKSNLNTTFISYLNHIRIEKSIELLENTTKSINEIAEIVGYNSLNNFYKNFKIEKGMT
                     PKVYKLNTKN"
BASE COUNT          695 a          319 c          200 g          757 t
ORIGIN      
        1 ttttgcaatt tatttaacta ttttgacttt ttaaattcgg attatataaa aaattttttt
       61 aaataaaaac tattaataag tggctctatt cctgactttg tgttgatttt tttctacatg
      121 taattgcttt atacaccata cagactaaaa ttaaaagccc catataacct gtatatggat
      181 ataaaatgtt tactaattta ccaaacggta aaaaacctcc tatacaagcc aaaatagcta
      241 ttactgttgt taccaattta aatttaggat gttcatcttc aacaattcta ttggttacag
      301 accataaaag tggaacagct gttgtataga tacctaatat taatgcaact gaaaaacata
      361 cacctacaat cggagatata ttatctgcta aataaagtga tggtatttct ttcatataca
      421 aatttcctat atctgaaatc atagccaaat acataactat accagcagtc ataaacacta
      481 ttccacctaa taaacctccc caaaaagcat cctttttact ttcaatagaa gctcccattc
      541 ctgttaaaaa aacaatcatt acaataatat ttaatgtatt atatattaca ccagaaacga
      601 ttggactttc tgatgctttt gtaacttcaa tatttttcat agcttctcca accatagata
      661 aaccgtcaaa atgcttaaac aagcttatta atccaacagc aattgtaaat actgctatca
      721 ctggtccaat acgtccaagt atgcttacta atttttctaa acccatagac actgtaatta
      781 aagtagcaac agccatcaat actcttccta agtaaggatt tataccatag tattcagtta
      841 aagttgagcc tgcacctgaa atcattacta taagaatccc aaataaaaat attggactaa
      901 accattcgta aaattttcct aaaatcttcc cacaataaaa agtgtaaatt cttgttggtt
      961 ctttaagttt taattctcta cctctagtta taacttcagc accaagaaat gaaaacaata
     1021 ccattgatat taatgctcca attaaaccca tatacccttg tgaggcaaaa aattgtagaa
     1081 tttcttgacc agtagcaaac ccagaaccaa ttgctgttgc tagataagcg cctgcaatac
     1141 agataatatt tttcatattc actttgtctg acatattaaa ttacctccat tataaagtta
     1201 ccttccttta agaaatataa actctcagta aattaaatga aaattctgtc tttttgaaac
     1261 agtatttaat tcactttttt tattttgtat atctttttct ttttatttat atatattttt
     1321 ttatataaat aggtacagct tttataaggt ttaatattat taaatatgtt taaagcgctt
     1381 taatttttat cataattaaa gtatacttat tcagacacac tcaaacaatt atctatattg
     1441 actttttatt tatcaatttc aatttttagt gttcagttta taaacttttg gagtcattcc
     1501 tttttctatc ttaaagtttt tataaaagtt atttaggcta ttatatccaa ctatttctgc
     1561 aatctcattt atactttttg tagtattttc aagtaactca atagattttt ctattcttat
     1621 atgatttaga tatgatataa aagttgtatt taaattactt ttaaaaatcc tagatatatt
     1681 agatggattg gttaaaaata atctagcaca atcatttaac tttaagtcat tgctatagtt
     1741 tagatttata tattccagta tctcatttaa taaatcatta ttggtatatt gatatccaat
     1801 aattttttct acagacttag taaattcttt catatccaat ggtttaagga gtatatcttt
     1861 tacatttaat ctcaaagctt tttgagcata ttcaaaatag ttaaatgcag ttattactac
     1921 aaagtttatt tttttagata aatgagatgt tttttctatt acttctaacc c
//
LOCUS       DAJMZY010000214         1958 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.219, whole genome shotgun sequence.
ACCESSION   DAJMZY010000214 DAJMZY010000000
VERSION     DAJMZY010000214.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1958)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1958)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1958
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.219"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            680..1147
                     /locus_tag="OE968_003758"
     CDS             680..1147
                     /locus_tag="OE968_003758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HCP7220963.1"
                     /translation="MITKFFSNILSVFLYFLLSLLGVAGIIFLCMIPMFLYDFSSDKV
                     IALIARILYFSDYFIVILFLIFIINSTKYSPFVLENVKRFKVMGFCLLINTIIECING
                     YNLNTNNIRIFGTDSGGISPLMVISFIFALMCFVIAETFDKAIKIKEDNDLTI"
     gene            1158..1373
                     /locus_tag="OE968_003759"
     CDS             1158..1373
                     /locus_tag="OE968_003759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCP7220964.1"
                     /translation="MAIVVNLDVMMAKRKISLKELAEKIDITNANLSILKTGKAKAIR
                     FTTLNEICKALDCQPGDILEYVEDEND"
BASE COUNT          744 a          219 c          210 g          785 t
ORIGIN      
        1 aaaatatcta ttatataaat atccactctt atgtttgaaa tccgtcatat agttttatcc
       61 ttcttatctt ttatatcaat aacttttttt aataaaattg acaaaactaa agtaaaaaac
      121 cttattgata atgaaacaaa tgatactata agttctgata ttatagtaat tgcatataaa
      181 tagacatcat aaaaataata taatattgtc actataaaat taaatgtaaa aatctcaaat
      241 ctaactaaat acacatatag gtatttttta agtttttagg tatttcttct gaaaatgatt
      301 tattgattga taccaattta cataatcttt ttaatataaa caatgataca atatatggga
      361 cagcacatat gtatatagct acttatatta cagttggcat attcgtattt gtaatgctta
      421 taccaatttt aaaatacacc atcagtacta atagtattaa aataatctat aataaagtta
      481 aaattattcc aattagtaca atattattta atattttaca actcatatcc ttttttatat
      541 aaatttacca ccttatacat tcttattttt agtgtatatt acaatggttt tatatattat
      601 atcaatattt tattattgaa attcaataaa ttatatatta taatcaataa tatactttat
      661 ataaaggaga tgatatttta tgattacaaa attttttagt aatatattat cagtatttct
      721 atattttcta ttatcacttt taggagttgc tggtataata ttcttatgta tgatacctat
      781 gtttttatat gattttagtt ctgacaaagt aattgcttta attgcaagaa tactatattt
      841 ttctgactac tttatagtca tcttattctt gatatttata attaatagta ctaagtattc
      901 cccattcgta cttgaaaatg taaaaaggtt taaagtaatg ggattttgtt tattgataaa
      961 cactataatt gaatgtatca atggttataa tttaaatact aataatataa gaatttttgg
     1021 aactgatagt ggcggtatct caccacttat ggttatctct tttatatttg cactaatgtg
     1081 ctttgtaatt gcagaaacat ttgataaagc tataaaaata aaagaagata atgatttaac
     1141 gatatagagg tgatgttatg gcaatagtag ttaacctaga tgtaatgatg gcaaaaagaa
     1201 aaatatcact taaagaattg gcagaaaaaa tagatattac aaatgcaaat ttatcaattt
     1261 taaaaactgg aaaagcaaaa gctattagat ttaccactct aaacgaaatt tgcaaagctt
     1321 tagactgtca gccaggtgat atacttgaat atgtagaaga tgaaaatgat taaaaaagag
     1381 tgtttagaaa cactcttttt tattatacta tatgattttt attcttttac tatattattg
     1441 acattaatat taactttgtt taaagtcata acaaaatatg ttctaagaaa gaaactgttc
     1501 ctttatctat ttgttatcca ttacctataa gaactgtatc acactaaata atacttttaa
     1561 attgataatt ttaccacaga ttcctatata cattcttttc tacataatat ttatttaaac
     1621 tgttagcaaa acatggaact ttttcattta cttatacctc catttatatt attgcatagc
     1681 ttatagctat gtgttataaa ttacattatt gatgatttta tctaacattt gtaatctttt
     1741 agatactctt tgaagttaca acactgttat actctaatta agtaaactaa atctgataca
     1801 agttggtgat tatatgaaaa gaaaactttc aacctatttt aaaggatata ttttaggttt
     1861 atgtatagca tttttattat ttacttttat attaaaaaaa ttaattatag aaaatatcat
     1921 tggaataata attggaactg gaattgcatt tttactga
//
LOCUS       DAJMZY010000215         1954 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.220, whole genome shotgun sequence.
ACCESSION   DAJMZY010000215 DAJMZY010000000
VERSION     DAJMZY010000215.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1954)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1954)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1954
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.220"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            complement(<1..230)
                     /locus_tag="OE968_003760"
     CDS             complement(<1..230)
                     /locus_tag="OE968_003760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HCP7220965.1"
                     /translation="MEELKDFLERQLNKKINIYPYENQKLDASSHLVTFNNAIYVIDF
                     LDKNNLDNLKGNFYLIYQSHIDFEYLKNIFYN"
     gene            complement(260..1369)
                     /gene="ugpC"
                     /locus_tag="OE968_003761"
     CDS             complement(260..1369)
                     /gene="ugpC"
                     /locus_tag="OE968_003761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003242648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HCP7220966.1"
                     /translation="MSEVILKNISKLYSNGFNAVKNINIDIKDKEFIVLVGPSGCGKS
                     TTLRMIAGLEEISEGELYIGDKLVNDIEPKDRDIAMVFQNYALYPHLSVYENMAFALK
                     LRKLPKDEIDKKVKEAAKILDLLPLLNKKPKTLSGGQRQRVALGRAIVRNPKVFLMDE
                     PLSNLDAKLRTAMRTEITKLHQQLGTTFIYVTHDQVEAMTMADRIVVMKDGVVQQIAT
                     PQDVYDYPANIFVAGFIGAPQMNFIDVILIEENDEIYAQNEHIKLKLNKEKHYDLIKD
                     NYINNEVVIGIRPEDIHVEDTFIKSNPDTCFKSRIEIKELMGAETYAHLKLGENTITI
                     RFDSKNRINVGDDLTLSVDNSRVHIFDKETTLAIR"
     gene            1803..>1954
                     /locus_tag="OE968_003762"
     CDS             1803..>1954
                     /locus_tag="OE968_003762"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220967.1"
                     /translation="MNLKKKEKIVKPVLKKLTEIVLNILSKKILNYAIYAISVLIVTK
                     VVINID"
BASE COUNT          672 a          238 c          238 g          806 t
ORIGIN      
        1 aaattataaa aaatattttt tagatattca aagtctatat gagattggta aattaaataa
       61 aagttgcctt ttaaattatc gagattattt ttatctagaa aatcaataac ataaatagca
      121 ttattgaaag taactaaatg gctactagca tctaactttt ggttttcata tggatagata
      181 tttatttttt tattaagctg tctttctaaa aaatctttta actcttccat aaagtctcct
      241 taaaaataag attatattct tatcttatag ctaaagtagt ttctttgtca aatatgtgta
      301 ctctactatt gtcaactgaa agtgttaagt catcaccaac attaattctg tttttactgt
      361 caaatctaat tgttatcgta ttttcgccta gttttaagtg agcataagtt tctgctccca
      421 taagttcttt tatttcaatt cttgatttaa aacaagtatc tggattagat ttaataaaag
      481 tatcttctac atgaatatct tctggtctga tacctataac aacttcatta ttaatataat
      541 tgtcttttat taaatcatag tgtttttctt tattcaattt aagcttaata tgttcatttt
      601 gtgcataaat ttcatcattt tcttctatta atattacatc aataaaattc atctgtggtg
      661 ctccaataaa tcctgcaaca aatatattag ctggataatc gtatacatct tgtggagttg
      721 caatctgctg aactactcca tccttcatta ctacgattct atcagccata gtcatagctt
      781 caacttggtc gtgtgttaca tagataaatg tagttccaag ctgttggtgt agcttagtta
      841 tctctgttct catagcagtt ctaagttttg catctaagtt ggatagaggt tcatccatta
      901 agaatacctt aggatttcta actattgcac gtcctaaggc aaccctttgt ctttgtcctc
      961 cagataatgt tttaggtttt ttatttaaaa gaggtagtaa gtctaatatt ttagcagctt
     1021 ctttaacttt tttgtctatt tcatctttag gcaattttct aagtttaagt gcaaatgcca
     1081 tgttttcgta aacagataag tggggatata aagcatagtt ttgaaaaacc atagctatat
     1141 ctctatcttt tggttctata tcattgacaa gtttatctcc aatgtatagt tctccttcag
     1201 agatttcttc aagaccagca atcattctaa gtgtagtcga tttaccacaa ccagatggtc
     1261 ctactaaaac gataaattct ttatctttaa tgtctatatt tatatttttt actgcattaa
     1321 atccatttga gtaaagtttt gatatatttt ttaaaattac ttctgacata atatcctcct
     1381 tgatatttaa attttaatta tatagtatca aattttttta ttatattaaa tgtgtaaaat
     1441 gactaaatgt atttgtttaa tatgtatagt tagtttttat attaagattt attataattt
     1501 agaaaatata ttttaatttt tttaattttt atgtataata atatatatat tttttagatt
     1561 aacaatatgg gatttaaatt attttttaat ttataatgaa ataatattat attagtagtt
     1621 ttggttaaca atgaggagtt tataaataag gtcatataag ttaaattata tcgattttat
     1681 ttaaataacc ccatatttat taattattag aaatatattt taattattga ctaaataata
     1741 aatactgtaa tataatggaa atacagttta ataaatataa aaagagaaag agggaatttt
     1801 aaatgaattt gaagaaaaaa gagaaaatag ttaagcctgt tttaaagaag cttacagaaa
     1861 tagtattaaa tatattatca aaaaaaatat taaactatgc tatatatgca atttctgttt
     1921 tgatagtaac aaaagttgtt ataaatatag attt
//
LOCUS       DAJMZY010000216         1938 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.221, whole genome shotgun sequence.
ACCESSION   DAJMZY010000216 DAJMZY010000000
VERSION     DAJMZY010000216.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1938)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1938)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1938
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.221"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            complement(101..1279)
                     /locus_tag="OE968_003763"
     CDS             complement(101..1279)
                     /locus_tag="OE968_003763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HCP7220968.1"
                     /translation="MKYHIFLIITTILIIELCNIYICKIASFRNKNITIHKNYKYIFL
                     IKPLTFLIIIFTKLPLPLYYILFYIVSHKLLLSRKSSTNNHFIPNMAVISFCILHLIT
                     VSTISLVKNTSPDIIFANMTYKLISILIASILDFILWYSMNKIKEHIYIITQNQIEFS
                     LFLKFIWFTLGYILFDSIQITFAPPSSLTSYFILGSNILLILQLIIFINHIYSIEKNI
                     YLEKEHNRLKMIKQEQLLKVNLLKKKANIDELTSAYNRKFAFEKIQHYIDNNLLFSLI
                     YIDLDKLKTINDTYGHLAGDNYIINFSSIVIENLGIDDIFARIGGDEFIVIMPKSNEN
                     TTKEFIEKISKIMDNTISFSYGIVEVSSENKMTVEEIINIADIRMYTNKQNNHKRNNN
                     "
BASE COUNT          709 a          187 c          251 g          791 t
ORIGIN      
        1 attaatcatt atgtccagat atttaaaaaa attataatga tagagataat aagataaaaa
       61 acatagtgag actacaagta agctcatgta aatattcatt ttagttattg ttccttttat
      121 gattattttg tttattagtg tacattctaa tatcagcaat attaataatt tcttctacag
      181 tcattttgtt ttcgctagaa acttctacaa taccatagct aaaagatatc gtattatcca
      241 taattttact tattttctct ataaattctt ttgtggtgtt ttcattagat ttaggcataa
      301 taactataaa ctcatctcct cctattctag caaatatgtc atctattcct aagttttcaa
      361 taactatact tgagaagtta ataatatagt tatccccagc taaatgtcca tatgtatcat
      421 ttatcgtctt taatttatcc aaatcgatat atatcaatga aaataataaa ttgttatcaa
      481 tgtaatgctg tattttttca aaagcaaatt ttcgattata tgctgatgtt aattcatcaa
      541 tgttggcttt tttctttaat aaatttactt ttagtaattg ttcttgtttt atcattttta
      601 gtctattatg ttctttttcc aaataaatat ttttttcaat ggaatatata tgattgatga
      661 atataattag ttgtaagatt aataatatgt tacttcccaa tataaagtag gaagttagag
      721 aacttggtgg agcaaatgta atttgtatac tatcaaataa tatatatcct aaagtgaacc
      781 agataaattt taaaaataga ctgaactcta tttgattttg agttattata taaatatgct
      841 cttttatttt attcatagag taccataaga taaaatctaa aatagaagct attaaaatac
      901 taattaactt ataggtcata tttgcaaata ttatatctgg acttgtattt ttaacaagtg
      961 atattgtact tacagtaata aggtgtaaaa tacaaaaact tattactgcc atattgggaa
     1021 taaaatggtt gttagtagaa ctttttctgc ttaagagcaa tttatgactt actatgtaaa
     1081 acaatatata atatagtggt aatggtaatt ttgtgaatat tattatcaag aaggttaatg
     1141 gttttattaa aaaaatatat ttgtaattct tatgtatagt tatatttttg tttctaaaag
     1201 atgctatttt gcatatgtaa atgttacata gttcgattat taatatagta gttatgatta
     1261 aaaatatatg gtatttcata gtacatcctc ttttaaagtg aaattgtatt tacttaaaat
     1321 agattagatt ttatatattc tattttacag tttttattta ggtacatgca aagagcttat
     1381 tatggatacc ttctttttta ttgcatgtgt ctgtgttata taaaatttaa aaagtattat
     1441 atcttaatat acagtatgta tgataactat gtgtccaaat atagtaatta tgtatggaaa
     1501 gtataatagt tatgtgtata agtatagtaa ttacatatag catgtatgat gactatgtgt
     1561 ccaagtatag taattatata tagtatatat gataactatg tgtataagta tagtaattac
     1621 atatagtatg tatgataatg tgtccaagta tagtaattat atagtatgta tgataactat
     1681 atgtccaagt atagtataat tacacatagc aaatataata gttatgtgtc caagtatagt
     1741 aattacatat agtatgtatg ataactatat gtccacgtat agtataatta catatagtaa
     1801 atatagtagt tatgtgtcca agtgtagtaa ttatatatag catgtataat aactatgtgt
     1861 ataaagtata gtaattacat atagcaagta taatagttat gtgtccaagt atagtaatta
     1921 tatatagtaa gtataata
//
LOCUS       DAJMZY010000217         1805 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.222, whole genome shotgun sequence.
ACCESSION   DAJMZY010000217 DAJMZY010000000
VERSION     DAJMZY010000217.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1805)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1805)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1805
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.222"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            complement(<1..92)
                     /locus_tag="OE968_003764"
     CDS             complement(<1..92)
                     /locus_tag="OE968_003764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011058338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220969.1"
                     /translation="MKDKWILCPVCGNKTRLKIRADTELKNFPL"
     gene            complement(131..418)
                     /locus_tag="OE968_003765"
     CDS             complement(131..418)
                     /locus_tag="OE968_003765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015574378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220970.1"
                     /translation="MSTLIIGFIVAGVLLIAEYLLCTKFRSPLWGGIIPLLILAGTIY
                     VFASGRIPFERPYIFPFVVVNTLFFGDWGTGRDKYKKIKQTEMEKMKAKDI"
     gene            complement(421..717)
                     /locus_tag="OE968_003766"
     CDS             complement(421..717)
                     /locus_tag="OE968_003766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009460866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2089 family protein"
                     /protein_id="HCP7220971.1"
                     /translation="MELDKIPQWILALEQEDATFLKNFALKSGSLKEIAKMYGVSYPT
                     VRLRLDKLIQKIEMCDQQEEEPFQTFIKGLAVDSRIDVETAKIIIEKYKKEKEK"
     gene            complement(806..1711)
                     /locus_tag="OE968_003767"
     CDS             complement(806..1711)
                     /locus_tag="OE968_003767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HCP7220972.1"
                     /translation="MFKKNKKQTENVKEKKVRTVKVGTHKKSVIALWVVLIASVSFGV
                     YKNFTAIDMHTVHETETIQLRLTDTNGIENFVKNFAKSYYTWNNSKEAIEARTQAISG
                     YLTKELQALNTDTIRKDIPVSSAVNGVQIWSVTQADENQFSVIFTVEQLITENGSTKT
                     VRSAYEVTVYVDGSGNMVLTKNPTITSIPVKSGYTPKAKESDGTVDAVTTDEINEFLT
                     TFFKLYPTATAKELSYYVNEGVLKPIGKDYVFSELVNPIYNRIDSQVTVSVAVKYLDQ
                     QTKATQVSQFDLVLEKSGSNWKIIK"
BASE COUNT          485 a          397 c          300 g          623 t
ORIGIN      
        1 aatagtggga aatttttaag ctctgtgtcc gctctaattt tcaacctcgt tttattaccg
       61 caaactggac ataaaatcca tttatctttc aataatgcgt tcctcctatc taagtataca
      121 gttttgtaat ttatatatct ttagctttca tcttttccat ttcagtttgc tttatctttt
      181 tatatttatc cctgccagta ccccaatctc caaaaaataa agtattgact acaacaaacg
      241 ggaaaatata tggtctttca aatggtattc tgccacttgc aaaaacatat attgttcctg
      301 ccaagataag caagggaata atacctcccc aaagaggact tctaaatttt gtgcagagaa
      361 gatactctgc aattaataaa actcctgcaa caataaagcc aataattaat gtactcatgg
      421 ttatttctcc ttttcttttt tatatttttc aataattatc tttgcagttt ccacgtcaat
      481 tcgagaatca accgctaacc ctttaataaa agtttggaaa ggttcttctt cctgctggtc
      541 gcacatttca attttttgaa ttaatttgtc taaacgtaat cgaacagtag ggtaagatac
      601 cccatacatt ttcgctattt cctttaatga accggattta agtgcgaagt ttttaagaaa
      661 agtagcgtcc tcttgctcta aggcaagaat ccattgaggg attttatcaa gctccaaaaa
      721 cacaactcct ttcatattat ctttaacaat attcagtata tcataaataa aattaaagtc
      781 aataagaatt taaacatcaa aataattatt ttataatctt ccagttgctc ccgctttttt
      841 ccagcaccaa atcaaattgt gatacctgcg ttgcctttgt ctgctggtcg aggtacttca
      901 cagccacgga aaccgtcact tgactgtcga tgcggttgta gatgggattt accagttccg
      961 agaatacata atctttcccg ataggcttta acacgccctc atttacataa taggacagct
     1021 ctttagcggt tgcggttggg tagagcttaa agaacgtcgt cagaaattcg ttgatttcgt
     1081 ccgtcgtcac agcgtccacc gttccgtcgc tttcctttgc ctttggcgtg tagccggatt
     1141 tcacgggtat gctggtaatg gtcggattct tcgtgagaac catgtttcca gagccatcca
     1201 catagaccgt gacttcatag gcggagcgta ccgtcttcgt gcttccattc tccgtgatta
     1261 actgttccac agtgaagatc acggagaact ggttttcatc cgcctgcgtg acagaccata
     1321 tctgtacccc attgaccgcc gaagacactg gaatatcctt gcggatggta tcggtattaa
     1381 gtgcctgcaa ttcctttgtc agataaccgc tgattgcctg cgtccttgct tcaatagctt
     1441 ctttgctgtt attccatgtg taataggact tcgcaaagtt cttcacgaaa ttttcaatcc
     1501 cgttggtatc ggtaagtctt aactgtatgg tttctgtttc atgtacggtg tgcatatcaa
     1561 tagcggtaaa attcttatat accccaaaac tcacgcttgc gataagcact acccacaatg
     1621 caatcacaga ttttttatgt gtaccgactt tcacagtacg cactttcttt tctttgacat
     1681 tctctgtctg tttcttattc ttcttaaaca tattttctaa gtcctttctt ttattttact
     1741 cgtcctgcac cgattaagtg ttgttgccag taactattat ttaagtctgc atatcctatc
     1801 ggatt
//
LOCUS       DAJMZY010000218         1673 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.223, whole genome shotgun sequence.
ACCESSION   DAJMZY010000218 DAJMZY010000000
VERSION     DAJMZY010000218.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1673)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1673)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1673
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.223"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            167..367
                     /locus_tag="OE968_003768"
     CDS             167..367
                     /locus_tag="OE968_003768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003723180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HCP7220973.1"
                     /translation="MNNGIVKWFNNEKGFGFISMEGRDDVFAHFSAIQTSGFKSLEEG
                     QQVSFDIVKGARGPQAENITIL"
     gene            complement(531..743)
                     /locus_tag="OE968_003769"
     CDS             complement(531..743)
                     /locus_tag="OE968_003769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220974.1"
                     /translation="MVCKIFITLKTILPKTQIIVTTHSPHILQIDSKEEMIVLDMAES
                     DNVYKKELKLGEYGVLGWTNEGLYLH"
     gene            1118..1300
                     /locus_tag="OE968_003770"
     CDS             1118..1300
                     /locus_tag="OE968_003770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="HCP7220975.1"
                     /translation="MFKFYNNATLMFLPGTNIKTISERLGHADIKITMNSYSQFLEEM
                     DREAFENLSKILFIVF"
     gene            1371..>1673
                     /locus_tag="OE968_003771"
     CDS             1371..>1673
                     /locus_tag="OE968_003771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220976.1"
                     /translation="MNIIKSITLLLTLLIVILMTGCSPRESASEVAKKYIDKMNSGDY
                     ETAYSLLSKDSKKKISIENLEEFQNILVSTKRIISYKIGKEKIIKKYKHDGKEYKNV"
BASE COUNT          662 a          192 c          227 g          592 t
ORIGIN      
        1 gcaatgtaaa acgtttaaat atatttttaa tattaagaat aattaaaatg ttaactaaaa
       61 aatataatta agtagacatt tctattaatc tatgatacaa tagtatttgt ggtaatacac
      121 aattaaatca agtatatctt gatataggtt aataggagta tttttaatga ataatggaat
      181 agtgaaatgg tttaataatg aaaaaggatt cggttttata tcaatggaag gtagagatga
      241 tgtgtttgct catttctcag ctatacaaac ttcaggattt aaatcattag aagaaggtca
      301 acaagtaagc tttgatatag ttaaaggtgc tagaggtcct caagcagaaa atataactat
      361 attataatat atagattttt cgggaaagac tctttttaga gtcttttttt attgttaata
      421 tatgtaagat aatcattggt gaagtaaata aggtatattg agtaatgttc ttgatagttt
      481 atatgctaat gaatttcaaa aaaataagca ctcctataaa aagagtgctc ttaatgtaaa
      541 tataaacctt cattggtcca gcctaatacc ccgtattctc caagttttaa ctctttttta
      601 tatacattat cactttcagc catatctaac acaatcattt cttctttaga atcaatttgt
      661 aaaatatgag gactgtgtgt tgtgacaatt atttgtgttt ttgggagaat tgtttttaat
      721 gtaataaaaa ttttacatac cacatagttg atataaaact taagactagc agactcataa
      781 gcaattagtt gcctctcttt acataccaca tagttgatat aaaacctaga ggctctcaga
      841 gaagttataa gatgtttagt aactttacat accacatagt tgatataaaa ctccaaaata
      901 aacttagcat ctccaatgtt tacacatata caatgctctt aaaattgcag tgaacgcgca
      961 atattgcaat tgataatact tatcatatat tctcaatacc ttatatttca actgctaaac
     1021 ctcaatttat cacaaatatc gctcactgca aaatttctat atttttatta tatcatagca
     1081 tataattaat attttcaatt aatttttaca tttaattatg tttaaattct ataataatgc
     1141 aactttaatg tttcttcctg gaactaatat aaaaactatt tcagaaagat taggtcatgc
     1201 agatataaaa ataactatga atagctactc tcagttttta gaagagatgg acagagaagc
     1261 atttgaaaat ttgagcaaaa tactatttat tgtattttaa agaagatgac ttattcaata
     1321 tttgatgcta gaatataatt aataaaaatt taattatagg tgattgtatt atgaatatta
     1381 ttaaaagcat aactttactc ttaacattat taattgtgat attaatgaca ggctgttccc
     1441 caagagaaag tgctagtgaa gttgcaaaaa aatatattga taagatgaac tctggtgact
     1501 atgaaacagc atatagttta ttaagtaaag atagtaaaaa aaaaattagt atagaaaatc
     1561 ttgaagaatt tcaaaatatt ttagttagta caaaaagaat aattagttat aaaataggta
     1621 aagaaaaaat cataaaaaaa tataaacatg atggaaaaga atataaaaat gtt
//
LOCUS       DAJMZY010000219         1668 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.224, whole genome shotgun sequence.
ACCESSION   DAJMZY010000219 DAJMZY010000000
VERSION     DAJMZY010000219.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1668)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1668)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1668
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.224"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     misc_binding    624..887
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            1038..1589
                     /locus_tag="OE968_003772"
     CDS             1038..1589
                     /locus_tag="OE968_003772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan transporter"
                     /protein_id="HCP7220977.1"
                     /translation="MKTNTKKLTLNAILLAMGLLIHQITPAIGLPMKPDVPLAMLFVI
                     LVLNRDDYKTCLIAGIVTGIFTALTSSFPGGQIPNVIDKTLTANIVFLLMNISYNMPF
                     IKKLAKKTQDTVVVAIIMPIGTLVSGTIFLLAAQAIVGLPGASFTALFLAVVLPAVLI
                     NLVAGIFLFKIVSLSIRRVSYQA"
BASE COUNT          697 a          161 c          255 g          555 t
ORIGIN      
        1 gtaaagttga aaaaacgaag tataagaact aaaaagtatg gatatcaaac tataaataaa
       61 tataaaagac aaaacgcaag aagacataat atcctaacaa aattaatatt gttcataata
      121 gtcatatttt tggttatagt tttagtagtg ctaatattta ttaaaagaaa gaagaaaaaa
      181 ttttactaaa aataattaaa agaatatcat ttttttaatc attggtatct atttaataat
      241 atgatgtaat taaaatggag taatattctg tttcaaagga ggcatataaa tacaggaatg
      301 agtattaaat gatggttaat taagtaaatt tattgataaa tgtacttaat taactttgaa
      361 gaatttaatt cctcatgaat caaaatataa aattacatca acagttattc acaaaattaa
      421 tataagaaga attagagcca aagagcagac tattagacca ttaaagtaat tattcataga
      481 attttgtata tgaaaagaaa tgtatagtat aatttacttt ttttataaaa aatagattac
      541 aaaatatatt ttttataaaa aggtattgac attttttaga aaaaagaata ttattatttt
      601 aaaacaaaat tcaatacaat aaattaaatc ctatgacaag gaagagtagt taaatttagg
      661 ttcagtatag agagctgagg atggtggaat cttagcaaga aaaaatttga tgaatggccc
      721 ttagaggaat aaattgaaat catagttttg agagtagact ttatcgtcag tcgcacgtta
      781 tagcgaataa ggtatgtaag tacctgataa tgagatgtat gaaaattgaa ttttatatta
      841 atttttatat aatttaggtg gcaacgcgga taatctccgt cctattagtt taggacggag
      901 ttttttattt tactgaaaat ttaaaagata gaaggtggtg agaaagatgt tatgaatttc
      961 aaaagctaaa gatgatgata tagtaggttg gcaaaaaaat aaattgaaaa ttaaaaaaat
     1021 aggaggaagt acaaaaaatg aaaacaaata caaaaaaatt aactttaaat gcaatacttt
     1081 tagcgatggg attattaata catcaaatca caccagctat aggattacca atgaagccag
     1141 atgtaccact agcaatgtta tttgtaatat tggttttaaa tagagatgat tataaaactt
     1201 gtttgatagc gggtatagta acaggaatat ttacagcact tacatcaagt tttccgggag
     1261 gtcaaattcc taatgtaata gataaaactc ttacagcaaa tatagtattt ttattaatga
     1321 atattagtta taatatgcct tttataaaaa aattagctaa gaaaacacaa gatactgtag
     1381 tagttgcaat aataatgcca ataggaactc ttgtaagtgg aactatcttt ttattagcag
     1441 ctcaagctat agttggtctt ccaggggctt catttacagc tttattctta gcagtagtat
     1501 taccagctgt tttaataaat ctagttgcag gaatattttt attcaagatt gttagtctat
     1561 caataagaag agttagttat caagcttaaa cacgaaataa tattttactt tataaagcat
     1621 tataataact aaataacata agaataaagt agattataac tattttat
//
LOCUS       DAJMZY010000220         1479 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.226, whole genome shotgun sequence.
ACCESSION   DAJMZY010000220 DAJMZY010000000
VERSION     DAJMZY010000220.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1479)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1479)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1479
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.226"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            <1..489
                     /locus_tag="OE968_003773"
     CDS             <1..489
                     /locus_tag="OE968_003773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HCP7220978.1"
                     /translation="DTTKTELTSNIETAKTELNTKIDQLIAGGSNVAYTQRVAIDDWV
                     EDAESGFKATVTHSLLTQRIVVNIIDATTKENIVPNFKIVDDNSIEIRSEVKVELNVY
                     VINGNAETHFINATVDDNRVSEMTTYSSKKIEDRLVNIEEKVNGGLSNIATSVNELIT
                     YC"
     gene            506..>1479
                     /locus_tag="OE968_003774"
     CDS             506..>1479
                     /locus_tag="OE968_003774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220979.1"
                     /translation="MQTEWNFNYANYVQNVSLPPGRYKLECWGACGGAVDTSDWTDCA
                     KGGYSKGEIVFKKRTNLQICVGQSGYEKVSEGSSLTRSGFNGAGAAGKVTTGSFAYSK
                     YGGGATDIRLYHPSATWGNTESLLSRILVAGGGGGMKNNFASARSIGHGGGYVGVNGV
                     GRDRDFCGGGSQYQGGTSYDTEEYHGSLGKGGYGNIGIGGGGGWYGGAGSYSNECGGG
                     GSGYALNKDSYKVPGYIPTPEYYLENIVMTTGGNTTKADGYAKITLLQALPFLTVSSY
                     NSTQATFKADHTDPALLTKIEWFIDDVLKETITTNLTEEKTINYTLED"
BASE COUNT          523 a          191 c          334 g          431 t
ORIGIN      
        1 gatacaacta aaacagaatt aacaagcaac atagaaactg ctaaaacaga gttaaatact
       61 aaaatcgacc aattaatcgc aggtggctca aatgttgcat acactcaaag ggtcgcaatt
      121 gatgattggg ttgaggatgc agaaagtgga ttcaaagcaa ctgtaacaca tagtttatta
      181 acacagagaa tagttgtaaa tattatagat gctactacaa aagaaaatat agttccaaat
      241 tttaaaatag ttgatgataa ttcaattgag attagaagtg aagtaaaagt tgagttaaat
      301 gtctatgtga taaatggaaa tgcagaaact cattttataa atgcaactgt agatgataac
      361 agagtatctg aaatgactac ttattcatct aagaaaatag aggacagatt ggttaatata
      421 gaagaaaagg taaatggtgg tttatctaat attgcaacaa gtgtaaatga gttgataact
      481 tattgttaga gaggagagtg agaaaatgca gactgaatgg aattttaatt atgctaatta
      541 tgtacaaaat gtttcattgc cacctgggcg atataaatta gaatgttggg gtgcttgtgg
      601 tggtgctgtc gatacaagcg attggactga ttgtgcaaaa ggtggttatt caaaaggtga
      661 gattgtattt aaaaaaagaa ctaatctaca aatttgtgtc ggtcaatccg gttatgagaa
      721 agtttctgaa ggttcaagcc ttactagaag tggttttaac ggtgcaggcg ctgctggcaa
      781 agttactact ggtagctttg cttattctaa atacggtggt ggagcaactg atataagact
      841 ttatcatcct agtgcaactt ggggtaacac cgaaagtttg ctttcacgca tacttgttgc
      901 aggcggtgga ggaggtatga aaaataattt tgcttctgct cgttctattg gtcatggtgg
      961 tggttatgta ggtgttaatg gagttggtcg tgacagagat ttttgtggcg gtggttctca
     1021 ataccaaggt ggaacaagtt acgacacaga agaataccat ggttcattag gaaaaggagg
     1081 ttatggtaac ataggaatag gtggtggagg gggttggtac ggtggtgctg gttcttattc
     1141 taatgaatgt ggaggtggtg gaagtggtta cgcactaaat aaagatagtt ataaggtacc
     1201 cggatatata ccaacacctg aatattatct tgaaaatata gtcatgacta ctggaggtaa
     1261 tactactaaa gcagatggtt atgctaaaat aacattacta caagcattgc catttttaac
     1321 agtatcttct tataattcta cacaggcaac atttaaagcc gaccacacag accctgcatt
     1381 acttacaaag atagaatggt ttatagatga tgtactaaaa gaaactataa caacaaattt
     1441 aacagaagag aaaacaatta attatacatt agaagataa
//
LOCUS       DAJMZY010000221         1462 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.227, whole genome shotgun sequence.
ACCESSION   DAJMZY010000221 DAJMZY010000000
VERSION     DAJMZY010000221.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1462)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1462)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1462
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.227"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            <1..425
                     /locus_tag="OE968_003775"
     CDS             <1..425
                     /locus_tag="OE968_003775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCP7220980.1"
                     /translation="ALDLIWNVFEEFESPDYCDEGITTFHQFIEYNSIIEKIKEKTLF
                     FWGCFDSKKLIGVLAIRNLNHICMLFVDKNYHKHGVAKKLMTTGIQYCICNKFNLTEI
                     TVNSSPYAVEVYHKLGFKDTAVEQIVDGIRFTPMKLLI"
     gene            complement(794..1351)
                     /locus_tag="OE968_003776"
     CDS             complement(794..1351)
                     /locus_tag="OE968_003776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCP7220981.1"
                     /translation="MRVSREIVIQATSDIVNKDGLNKVSLKVIAEKLGIRTPSLYNHI
                     ESLDDLLLEVAHKGMREMNSQMIKAAIGNFGDTAIKCISIAYFNFIISNPGVYETIQW
                     ATWHGNNETLEIFDEYKSLLEKLILSCNLNTKNTGEVLNLIMSVLHGYSTLQLGKSFL
                     SKEEAIKGLVDSIDTVLLGIHKKYD"
BASE COUNT          518 a          209 c          154 g          581 t
ORIGIN      
        1 atgcattaga cttaatctgg aacgtatttg aagaatttga atctccagat tattgtgatg
       61 aaggaattac gacatttcat caatttatag aatataactc tattattgaa aaaatcaaag
      121 aaaaaactct cttcttttgg ggttgttttg actctaaaaa acttattgga gtcttagcta
      181 ttagaaattt aaatcatata tgtatgttat ttgtagataa aaactatcat aaacatggtg
      241 ttgcaaaaaa attaatgact acaggcatac aatactgtat ttgtaataaa tttaatttaa
      301 ctgaaataac tgtaaattca tcaccttatg ctgttgaagt ttatcataaa ttaggattta
      361 aagatactgc tgttgagcaa attgttgacg gtatacgttt tacacctatg aaattgttaa
      421 tataataaat taaataaaaa gcaaagtctc ttaaatattt tatagttact ttgcttttaa
      481 accaagattt aaaataatac tatctttttt gttttttaat aatatacttt aaaatcctta
      541 ctaatatgaa ctataattta ttttttgata tcctttttga ttaacatata aattaattca
      601 attattaaac ataaactatg ttgtttctct ttatatctct tctttgtaaa caatattggg
      661 catttgaaaa taaatattct taaaatatac tgttctcctg ttgattttcc tttggtacaa
      721 atgataaaaa tttaatttac atgccccata atgaagtgtt caataaataa gttaaaataa
      781 tttatttacc tccttaatca tattttttat gaatacctaa taacacagta tcaatagaat
      841 cgactaaacc ttttatagct tcttctttac tcaaaaatga tttcccaagt tgcaaagtcg
      901 aataaccatg aagtacactc attattaagt ttaatacttc acctgtattc tttgtattta
      961 gattacaaga aagaataagt ttttctaata aggatttata ttcatcaaag atttctaatg
     1021 tttcattatt tccatgccaa gtagcccact gaattgtttc ataaacacca ggattagaaa
     1081 ttataaaatt aaagtatgct atacttatac actttatagc tgtatctcca aaatttccaa
     1141 tagccgcctt tatcatttga ctattcatct ctctcattcc tttatgagct acttcaagta
     1201 ataaatcatc tagactttct atatgattgt acaaagatgg tgtacgtatt cctagctttt
     1261 ctgcaataac ttttaaagaa actttgttaa gcccatcttt attaactata tctgatgtag
     1321 cttgtataac tatttctcta ctaacacgca tgattttccc tctttcattt aaaattaatt
     1381 actttattag tttaactaat ctaattagtt tcgtcaatta ttgtaattta taaaattctt
     1441 tatactatta taaaatcttg ac
//
LOCUS       DAJMZY010000222         1393 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.229, whole genome shotgun sequence.
ACCESSION   DAJMZY010000222 DAJMZY010000000
VERSION     DAJMZY010000222.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1393)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1393)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1393
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.229"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            240..1067
                     /locus_tag="OE968_003777"
     CDS             240..1067
                     /locus_tag="OE968_003777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AIM24 family protein"
                     /protein_id="HCP7220982.1"
                     /translation="MDLSKKVKILENASDGKSEFEILEFEKLEGASSPLMAMGLYFAR
                     EAGLKARQIKIKLNNSSIKTEAGALYYYKGNISSETKIGGVGGLFKKGISGALTNESM
                     MKPVYKGTGEVYLEPSFRHYLFMSLDNDSIIVDKGLFYCCSDTIEVKAFTQKNFSSAL
                     LGGEGFFQIELSGTGVIVLECVVPQSEIVEYELKNGEELKVDGNFAIARTSGVNFSVT
                     KSDKSLIGSALNGEGFLNTFTGSGTVWLAPTQVMYEKLSFGAMPTNDNMNNKVSKQK"
BASE COUNT          524 a          152 c          211 g          506 t
ORIGIN      
        1 ataattttaa catgcccata aaatataata cccacaaatg ataaataata ctcaaaatgt
       61 ctattgaaat aactatacat ccttaaataa cttaacttaa atctaaacat ttcaaaaact
      121 tcttaaaaat atgtaaaaat ttgatgataa agtagcgatt ttttcaaaaa aaatgtaata
      181 tagagttata tcttataata ttttagagat aaattttatc atagtgggga gaaatttgta
      241 tggatttaag caaaaaagta aaaattttag aaaatgcatc agatggcaaa agcgaatttg
      301 agatattaga atttgaaaaa cttgagggag cttctagccc attaatggca atgggattat
      361 attttgctag agaagctggt ttgaaagcta gacaaattaa gataaaatta aataattcat
      421 caataaaaac agaagctggt gcattatact attataaagg aaatatatct tctgaaacta
      481 agattggtgg tgttggaggt ctttttaaaa aaggaatatc aggagcactt actaatgaat
      541 caatgatgaa acctgtatac aaaggtactg gagaagttta tttggaacct tcttttagac
      601 attatttatt tatgagtctt gataatgatt ctataattgt tgataaagga ttattctatt
      661 gttgctctga tacaatagaa gtaaaagcat ttacacaaaa gaacttctca tctgctttac
      721 ttggtggtga aggcttcttc caaatagaat taagtggtac tggtgtaatc gttctggaat
      781 gtgttgtacc tcaaagtgaa attgtagagt atgaattgaa aaatggtgaa gaattaaagg
      841 tagatggtaa ctttgcaata gcaagaacat ctggtgttaa tttttctgtt acaaaatcag
      901 ataaatcttt aattggttct gctttaaatg gtgaaggttt cttaaataca tttactggta
      961 gtggtacagt ttggctagct ccaactcaag taatgtatga aaaactaagt tttggagcaa
     1021 tgcctactaa tgataatatg aataataaag tttctaagca aaaatagttg ttttataaat
     1081 atttattaaa tcattattga ttttataaag tcactataaa ttttattaga ttattataaa
     1141 atcagagtgt ggaaatattt atgtgtattc tttaaataaa aatttccaca ttctgtaaag
     1201 ttattatact tgatatataa aattcaattt aggaacatag tctaacattt ataaacatat
     1261 taaggtaatg atttctcttg gtagttattc tcatatctta ttctttgatt atatttatct
     1321 tattcctagc ccttatgtca tattatattt cttatcttat tatttataat tagcattaac
     1381 ttatctaaaa tct
//
LOCUS       DAJMZY010000223         1393 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.230, whole genome shotgun sequence.
ACCESSION   DAJMZY010000223 DAJMZY010000000
VERSION     DAJMZY010000223.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1393)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1393)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1393
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.230"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            complement(272..763)
                     /locus_tag="OE968_003778"
     CDS             complement(272..763)
                     /locus_tag="OE968_003778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfbM family protein"
                     /protein_id="HCP7220983.1"
                     /translation="MGMIGCYTKISEENVFKLQQAEENLQDFVFEDANENSTINIDKA
                     WHAIHFTLTGCPFGGDDDNIFSKLVLSGNILMEIDGEFPVMLITANDVKKLSKAMNSL
                     EEQAFRKRFNINEMLENNIYPVMNDESEDDFFEYVWANLIELKKFIQEASNDGLAVIF
                     FIM"
BASE COUNT          535 a          183 c          122 g          553 t
ORIGIN      
        1 atccaaaaga attactggat ataataggat agggtattta gccttttaag ataaataaaa
       61 atatctgcaa ctatatattg caaaaattta aaactaattt atatatgcta atataaatat
      121 ttataaagac ataagacaaa tttacctaca gatttaaatt taacttatat attttaaaag
      181 gctaatataa tatgtatttt cttctataca atcaaaaggc ttcatatcta agatatgtga
      241 tgacactaat attcacaatt tttagtaatt atcacattat aaaaaatatt acagctagtc
      301 catcattaga tgcttcttgt ataaactttt taagctcaat tagatttgcc catacatatt
      361 caaaaaaatc atcttcactc tcatcattca taacaggata aatattattt tctaacatct
      421 cattaatatt aaatcttttt ctaaatgctt gttcttccaa actgttcatt gcttttgata
      481 gtttttttac atcatttgct gtaatcaaca tgacaggaaa ttctccatca atttccataa
      541 gtatgtttcc acttagtact aatttgctaa atatattatc atcatctcca ccaaaaggac
      601 aacctgtcaa agtaaagtga atggcatgcc atgctttatc aatattgata gtactatttt
      661 cgttggcatc ttcaaaaaca aaatcttgta aattttcttc tgcttgctgt aatttaaaaa
      721 cattctcttc acttatttta gtataacatc ctatcattcc cataattaca ttcctcctaa
      781 gtagcgtttt tttaattgta acttataatt aaacttagtt acaataaaat atattgagaa
      841 aagtattatt tcatcttaaa tttaaatacc tatattatca actaaaattc tgtgtttata
      901 gcgtaagtat tattttttcc taaaaattaa atgaatcaga ggttctatag gcaatattga
      961 ctataaataa gaactattac tttttaaaaa aaatttaaga aattatactg tagaatcatg
     1021 ctctacttat tagctttaaa taaaaaataa atcatgttct caaattaaat aataaataac
     1081 aataaattta aattttaaac tataagagtt tctgaagtgt taataagcat accaataatt
     1141 atatgtgtaa gaatttgatt taatagatat gaataatttt tacattaatt ataaatatat
     1201 taacctattg ttataaattc taaaaaagaa aagttatctt aaataaaaaa taagtgtatc
     1261 ttaaatttta aatgatacac ttatttttat attgaaatta tattttttaa tatctattct
     1321 taattaggta tttttaaatt atctgtttac attaaatatt tcttaattac ttatctttca
     1381 gctagctttt tct
//
LOCUS       DAJMZY010000224         1374 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.231, whole genome shotgun sequence.
ACCESSION   DAJMZY010000224 DAJMZY010000000
VERSION     DAJMZY010000224.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1374)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1374)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1374
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.231"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            201..539
                     /locus_tag="OE968_003779"
     CDS             201..539
                     /locus_tag="OE968_003779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCP7220984.1"
                     /translation="MANIGKIIGDRIKVYRTKLGYSQEFLAEKAGLHPTYIGQIERAE
                     TNTSINIIMKIATALDIPLELLFANIITTEGVDNSVPLECYEMINKLTEKEQIAMLEL
                     IKCIIKYKEI"
     gene            561..878
                     /locus_tag="OE968_003780"
     CDS             561..878
                     /locus_tag="OE968_003780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCP7220985.1"
                     /translation="MNYIGKRLKEERKKANLTSKEFANMVGVSPWYITQIESGKKNPS
                     LKTFIKFVNILNISADVLIKDITSTGKTYLENDINEELKDLNSRELNLISQIIDIIKK
                     NKI"
     gene            1028..>1374
                     /locus_tag="OE968_003781"
     CDS             1028..>1374
                     /locus_tag="OE968_003781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220986.1"
                     /translation="MIVIEGSDKFKIAKEYIDVEYTLFSKVTFRYEKLKFKDNAELEK
                     IKMFKYKNGYIPNKLNLSFGYGFSSYKKQIIRETVDTLRLTEIFSSENIEDIKFIKDG
                     TKKLEISIEKVVK"
BASE COUNT          599 a          133 c          204 g          438 t
ORIGIN      
        1 tatgaaatta tgaaaatatt tctctaatta aaaatatgat ttatccatat ttgtttattg
       61 tagatacaga ctatacaaaa ataaatagca cttatttcag tataaaaaca tatatagtct
      121 atatttagac taaaaaagta taaatagtct atataaaaca acttaaacta tgaatataat
      181 ctaaagtgga gggataataa ttggcaaata taggaaaaat aataggagat agaataaaag
      241 tctatagaac aaaattggga tatagtcaag agtttctagc agaaaaggca ggtttacatc
      301 caacatatat tggtcagatt gaaagagctg agacaaatac atctatcaat attataatga
      361 aaattgctac tgctttagac ataccacttg aattgttatt tgcaaatatt attacaacag
      421 aaggcgttga taactctgta cctttagaat gttatgaaat gattaataaa ttaactgaaa
      481 aagaacaaat tgcaatgcta gagttaataa agtgcatcat taaatacaaa gaaatataag
      541 tgagggaaat agtaacaata atgaattata taggtaaaag acttaaagaa gaacggaaaa
      601 aagcaaattt aacttcaaaa gaatttgcaa atatggttgg agtatcgcct tggtatataa
      661 ctcaaatcga aagtggtaaa aagaatccaa gtcttaaaac attcataaaa tttgtaaata
      721 tattaaatat ttctgcagat gttcttataa aagatattac ttccactgga aaaacatatt
      781 tagaaaatga tataaatgaa gagttaaaag acttaaattc aagagaacta aatctgatat
      841 cacagattat agacatcata aaaaagaata aaatataatt ctttatattt tatataaaaa
      901 aaaaggttat ttgaaataaa taaccttttt ttgtcttttt gtgttaacat tgtcttatag
      961 tgctaatgag tactattaga ccatgttcta tggccttatt ttaatataaa acgattggag
     1021 ataggctatg attgtgattg aaggtagcga taaatttaag attgcaaaag aatatattga
     1081 tgtagaatat actcttttta gcaaagtaac ttttaggtat gaaaagttga aatttaaaga
     1141 taatgctgaa ttggaaaaaa ttaagatgtt taaatataaa aatggctaca tccctaataa
     1201 attaaacctt tcttttggat atggattctc ttcttataaa aagcaaataa ttagagaaac
     1261 tgtagatact ttaagattga cagaaatttt ttcaagcgag aacatagaag atattaaatt
     1321 tataaaagat ggtacaaaaa aattagaaat tagcatagag aaagttgtga aatt
//
LOCUS       DAJMZY010000225         1337 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.232, whole genome shotgun sequence.
ACCESSION   DAJMZY010000225 DAJMZY010000000
VERSION     DAJMZY010000225.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1337)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1337)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1337
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.232"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            27..101
                     /locus_tag="OE968_003782"
     tRNA            27..101
                     /locus_tag="OE968_003782"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:59..61,aa:Thr,seq:tgt)
     gene            116..200
                     /locus_tag="OE968_003783"
     tRNA            116..200
                     /locus_tag="OE968_003783"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:150..152,aa:Tyr,seq:gta)
     gene            210..293
                     /locus_tag="OE968_003784"
     tRNA            210..293
                     /locus_tag="OE968_003784"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:244..246,aa:Leu,seq:tag)
     gene            323..399
                     /locus_tag="OE968_003785"
     tRNA            323..399
                     /locus_tag="OE968_003785"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:357..359,aa:Arg,seq:tct)
     gene            407..482
                     /locus_tag="OE968_003786"
     tRNA            407..482
                     /locus_tag="OE968_003786"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:440..442,aa:Gln,seq:ttg)
     gene            571..659
                     /locus_tag="OE968_003787"
     tRNA            571..659
                     /locus_tag="OE968_003787"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:605..607,aa:Ser,seq:tga)
     gene            663..738
                     /locus_tag="OE968_003788"
     tRNA            663..738
                     /locus_tag="OE968_003788"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:696..698,aa:Phe,seq:gaa)
     gene            745..818
                     /locus_tag="OE968_003789"
     tRNA            745..818
                     /locus_tag="OE968_003789"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:779..781,aa:Met,seq:cat)
     gene            833..909
                     /locus_tag="OE968_003790"
     tRNA            833..909
                     /locus_tag="OE968_003790"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:867..869,aa:Ile,seq:cat)
     gene            933..1009
                     /locus_tag="OE968_003791"
     tRNA            933..1009
                     /locus_tag="OE968_003791"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:967..969,aa:Pro,seq:tgg)
     gene            1017..1093
                     /locus_tag="OE968_003792"
     tRNA            1017..1093
                     /locus_tag="OE968_003792"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1051..1053,aa:His,seq:gtg)
     gene            1102..1177
                     /locus_tag="OE968_003793"
     tRNA            1102..1177
                     /locus_tag="OE968_003793"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1135..1137,aa:Lys,seq:ttt)
     gene            1185..1258
                     /locus_tag="OE968_003794"
     tRNA            1185..1258
                     /locus_tag="OE968_003794"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1217..1219,aa:Cys,seq:gca)
     gene            1265..1336
                     /locus_tag="OE968_003795"
     tRNA            1265..1336
                     /locus_tag="OE968_003795"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1297..1299,aa:Asn,seq:gtt)
BASE COUNT          320 a          309 c          355 g          353 t
ORIGIN      
        1 ccccttccag gtcgccaaaa taaaatgctg gtgtggctca acggtagagc agctgacttg
       61 taatcagcag gttgtaggtt cgattcctat caccagctcc atgtaaaatt aatacggagg
      121 atttcccgag cggccaaagg gggcagactg taaatctgtt gtcatcgact tcggtggttc
      181 gaatccacca tcctccacca aaaaaatgcg cggatgtggc ggaattggca gacgcactag
      241 acttaggatc tagcgccatt ggcgtggggg ttcgactccc ttcatccgca ccatttttgt
      301 ttgatataca tatatatatt gtgggtgcat agctcagctg gatagagcaa cgcccttcta
      361 aggcgtgtgt ccggggttcg aatccctgtg cgctcaccac atatattggg gattagccaa
      421 gtcggtaagg cacatgactt tgactcatgt atgcgtaggt tcgagtcctg catccccagc
      481 caaatgatgt attactaagc tatatttgaa ttatttttat tttaaatata gttaggttca
      541 attttagaat aagtttaagt atccgaatgt ggagaggtgt ccgagtggtt taaggagctg
      601 gtcttgaaaa ccagtgactt cgaaaggggc cgtgggttcg aatcccaccc tctccgccaa
      661 atgcccagat agctcagtcg gtagagcagg ggactgaaaa tccccgtgtc ggtggttcga
      721 ttccgcctct gggcaccaaa atatggcggt atagcttagt tggctagagc gttcggttca
      781 tacccgaaag gtcataggtt cgactcctat taccgctact aaaatttaat gtgggccatt
      841 agctcagttg gttagagcgc ccggctcata accggtaggt ctggggttcg agtccctgat
      901 ggcccaccac attaaattaa ttaatataaa ttcgaggtgt agcgcagttt ggtagcgcac
      961 atggtttggg accatggggc cgggggttcg agtcccttca cctcgaccaa tataaggtgg
     1021 gtatagctca gttggttaga gcgccagatt gtggctctgg aggtcgtgag ttcgactctc
     1081 attatccacc ccaattcata tggtctatta gctcagtcgg tagagcacct gacttttaat
     1141 cagggtgtcc cgcgttcgag tcgcggatag atcaccaaaa aggtggcgac atagccaagt
     1201 ggtaaggcag tggactgcaa ctccttgatc cccagttcga atctgggtgt cgcctccaaa
     1261 atattccaag gtagctcaac ggtggagcaa ccggctgtta accggtaggc tgtgggttcg
     1321 agccccaccc ttggagc
//
LOCUS       DAJMZY010000226         1301 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.233, whole genome shotgun sequence.
ACCESSION   DAJMZY010000226 DAJMZY010000000
VERSION     DAJMZY010000226.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1301)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1301)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1301
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.233"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            <1..>1301
                     /locus_tag="OE968_003796"
     rRNA            <1..>1301
                     /locus_tag="OE968_003796"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          349 a          280 c          391 g          281 t
ORIGIN      
        1 agctgaggcc gaaaggcgta ggtgatggac aacaggttga tattcctgta ctaccgataa
       61 ccgtttgaga gaagggatga cacagtagga taagctaagc acactgttgg ttatgtgtgc
      121 ccaagcattg aggcagtcaa agtaggcaaa tccgctttga taatgctggg atgtgatggg
      181 gagcgaaatt tagtagcgaa gtagctgatt tcacactgtc aagaaaagtc tctatcgagg
      241 ttaaaggtac ccgtaccgca aaccgacaca ggtgggtgag gagagtatcc taaggccagc
      301 gagagaactg ttgttaagga actcggcaaa atgaccccgt aacttaggga taaggggtgc
      361 caccatcagg tggccgcaga gaataggccc aagcgactgt ttaccaaaaa cataggtttc
      421 tgctaagtcg caagacgatg tataggagct gacgcctgcc cggtgctgga aggttaaggg
      481 gatctgttag agcaatcgaa gcagtgaact taagccccag taaacggcgg ccgtaactat
      541 aacggtccta aggtagcgaa attccttgtc gggtaagttc cgacccgcac gaaaggcgta
      601 acgatttggg cactgtctca acaacagact cggtgaaatt gtaattccgg tgaagatgcc
      661 ggatacctgc gacaggacgg aaagacccca tggagcttta ctgtagcttg acattgggtc
      721 ttggtactac atgtacagga taggtgggag gctttgaaac caggacgcca gttttggcgg
      781 agccatcctt gggataccac ccttgtagta ctgggactct aaccataggc catgaatctg
      841 gtcttgggac actgtcaggt gggcagtttg actggggcgg tcgcctccca aaaggtaacg
      901 gaggcgctca aaggttctct cagtacggtc ggaaatcgta cgtagagtgt aaaggcaaaa
      961 gagagcttga ttgcaagaca tacaggtcga gcaaggatga aaatcggact tagtgatccg
     1021 gtggttctgc gtggaagggc catcgctcaa cggataaaag ctaccctggg gataacaggc
     1081 ttatctcccc caagagtcca catcgacggg gaggtttggc acctcgatgt cggctcatca
     1141 catcctgggg ctgtagtagg tcccaagggt tgggctgttc gcccattaaa gtggtacgcg
     1201 agctgggttc agaacgtcgt gagacagttc ggtccctatc cgtcgcaggc gtaggaaatt
     1261 tgagaagacc tgtccttagt acgagaggac cgggatggac g
//
LOCUS       DAJMZY010000227         1290 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.234, whole genome shotgun sequence.
ACCESSION   DAJMZY010000227 DAJMZY010000000
VERSION     DAJMZY010000227.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1290)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1290)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1290
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.234"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            complement(<1..1288)
                     /locus_tag="OE968_003797"
     rRNA            complement(<1..1288)
                     /locus_tag="OE968_003797"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          281 a          369 c          251 g          389 t
ORIGIN      
        1 gccaacattc tcactcccat actgtccaca tgtccttacg gtcatgcttc aacccgtatg
       61 ggaagctccc ctacccatca ttactgatgc cgtagcttcg gtagtaagtt ttagccccgg
      121 aaatcttcgg cgcaggatca ctcgaccagt gagctattac gcactctttg aatgagtggc
      181 tgcttctaag ccaacatcct ggttgtctgt gcaatcccac atcctttacc acttaactta
      241 catttaggga ccttagctga cgatctgggc tgttgccctt tcgactatga atcttatcac
      301 ccacagtctg actcccaagt ataagatgac ggcattcgga gtttgatagt cttcggtagg
      361 tgcaataccc cctaggacat tcagtgctct acctccgtat ctctcacctt gaggctagcc
      421 ctaaagctat ttcggggaga accagctatc tccgggctcg attggaattt caccgctacc
      481 cacaagtcat ccccgagctt ttcaacgctc gtgggttcgg acctccacga aattttactt
      541 tcgcttcatc ctgctcatgg gtaggtcgcc cggtttcggg tctacgtcaa gtaactgaac
      601 gctcagttaa aactcgcttt cgctacggct ccgcacctta agtgcttaac cttgctactt
      661 aacgtaactc gttggcccgt tctacaaaaa gtacgcggtc acacaagaaa tgtgcttcca
      721 cagcttgtaa gtgcagggtt tcaggttcta tttcactccc ctcccggggt tcttttcacc
      781 tttccctcac ggtactatac gctatcggtc actaggtagt atttagcctt ggagggtggt
      841 ccctcctgct tcccacaggg tttcacgtgt cccgtggtac tctggatcat atctaaagtc
      901 ttctcgttta acatacagga ctattacctt ctgtggtggg tctttccaaa cctcttcaat
      961 tacgatacct cttcgttatg atatgtccgc aaccccaata aagaaaactt tattggtttg
     1021 ggctaatccg cgttcgctcg ccgctactta cggaatcgaa tttctttctc ttccttcagg
     1081 tacttagatg tttcagttcc ctgagttccc ctcattaagc tatgtattca cttaatgata
     1141 cttagacatt actctaagtg agtttcctca ttcggaaatc ttcggatcaa agtttacgtg
     1201 caactccccg aagcttatcg cagcttatca cgtccttcat cggctcctag tgccaaggca
     1261 tccgccctgc acccttaata acttgaccag
//
LOCUS       DAJMZY010000228         1289 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.235, whole genome shotgun sequence.
ACCESSION   DAJMZY010000228 DAJMZY010000000
VERSION     DAJMZY010000228.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1289)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1289)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1289
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.235"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            71..1183
                     /locus_tag="OE968_003798"
     CDS             71..1183
                     /locus_tag="OE968_003798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HCP7220987.1"
                     /translation="MNAFIRKRNKNYVVYLEFEDEKTGKRKQKNMGTFDKKREASKRL
                     NEVKESLYNDGFLVPSEITVSEFLLDFLNKYSENISLATYNNYVSICKNYINPSIGKY
                     KIQDLHPVHIQNYIDKLSYKLNPQSIKIHINILKLAIKRAYRLKLIKENVMDSIEAPR
                     YKKFKNEIYDREQMIKLLDLAKNTEMELPINLAIGLGLRISEVLGLTWDNIDFEENTI
                     TVNKITSRINGSVILKEPKTESSVRKISSPKELMSLLKEYKIKQNKNLLKSSIRNNNN
                     LLFFNKKCEPIAEDVMSKKFKRFLEKNELPHIRFHDLRHSHVTLLINSKVPIKVISER
                     VGHSNISTTLSVYSHVLKEMDKEASDKISESLFNAN"
BASE COUNT          548 a          131 c          174 g          436 t
ORIGIN      
        1 tatttcaaaa ttattttgtg atatatatat gttataataa atgtataaaa ttttgattgg
       61 tgggttatat atgaatgcat ttattagaaa aagaaataaa aactatgttg tttacctgga
      121 atttgaagat gaaaaaacag gtaaaagaaa acaaaaaaat atgggtactt ttgataaaaa
      181 aagggaagca agtaaaagac taaatgaggt aaaagaaagc ttatataatg atggtttttt
      241 agtaccaagc gaaattacag tgtcagaatt tctattagat tttctaaata aatatagtga
      301 aaatatatct ttagctacat ataataatta tgttagtatt tgtaagaatt acattaatcc
      361 atctattgga aaatataaaa tacaagactt acatccggtt cacatacaaa actacataga
      421 taaactatct tataaactaa atcctcaatc aattaagatt catataaata tattgaaact
      481 tgcaataaaa agagcttata gactcaaatt aataaaagaa aatgttatgg atagtataga
      541 ggctccaaga tataaaaaat ttaaaaatga gatttatgat agagaacaaa tgataaaatt
      601 attagattta gcaaaaaata cagaaatgga attacctatt aatttggcta ttggattagg
      661 tcttagaatt tcagaagttt taggtctaac ttgggataat attgattttg aagaaaatac
      721 aataacagta aataagataa cttcccgaat taatggttct gttattctca aagagccaaa
      781 gacagaaagc tctgttagaa aaatatcttc tcccaaagaa ttaatgtctt tattaaaaga
      841 atataaaata aaacagaata aaaatttatt aaaatcttcc attagaaata ataataattt
      901 gttgtttttc aataagaaat gtgaacctat tgctgaagat gttatgagta aaaaatttaa
      961 aagattttta gaaaagaatg aattacctca tattagattc catgatttaa gacactcaca
     1021 tgttacttta cttataaatt ctaaagtacc tataaaggtt atatccgaga gagtaggaca
     1081 ctcaaatata agtactactc taagcgttta ttctcatgta cttaaagaaa tggataagga
     1141 ggcttctgac aaaatttctg aaagtttatt taatgctaat taatattaat ttatcttagc
     1201 tttaaattag cttagcttat tgagatagat tcattaatat taaatgtatc tatctcaaat
     1261 taataactac ttaaataatc tgttttatt
//
LOCUS       DAJMZY010000229         1274 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.236, whole genome shotgun sequence.
ACCESSION   DAJMZY010000229 DAJMZY010000000
VERSION     DAJMZY010000229.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1274)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1274)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1274
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.236"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            <1..171
                     /locus_tag="OE968_003799"
     CDS             <1..171
                     /locus_tag="OE968_003799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HCP7220988.1"
                     /translation="MSWEDEENLIVRISQIETRLLSIDGVLDITNTMINDVKSNLTID
                     SNSIVVRGEVVG"
     gene            164..781
                     /locus_tag="OE968_003800"
     CDS             164..781
                     /locus_tag="OE968_003800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YmfQ family protein"
                     /protein_id="HCP7220989.1"
                     /translation="MDKEINLINYLPQILQDKEEYIKVFNVENKEIKTLHEKLNDLSS
                     DQFLEDLTPSGIKRWEKIMSITPKSNESLEDRRFRIFSKYISKLPYSERFLRNWLDSI
                     VGEGNYELTINNATYNIHLESDARNQDWFEEVHSFVSSIKPCNMTLDYTRVLVSKDNY
                     MNFGITTLIGQEITIYPWSPPDIETYGEIDVLTGNGVGYQEITIF"
     gene            793..>1274
                     /locus_tag="OE968_003801"
     CDS             793..>1274
                     /locus_tag="OE968_003801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HCP7220990.1"
                     /translation="MAIDKSYYTIITDVGKAKIANASVTGNKVGFVKIQLGDGGGSEY
                     TPTESQTALKNVVWEGNIGNTTTDETAPNCIILESLIPSSVGGFMIREIGYLDDENNL
                     IAISKYKECYKPSIEQGAVVDMKVKTVLIVSNVNNIELKIDPTIIFATLKDIQDLETK
                     "
BASE COUNT          522 a          141 c          244 g          367 t
ORIGIN      
        1 atgagttggg aagatgaaga aaacttaata gtccgtatat ctcaaattga aactagatta
       61 cttagtatag atggagtgtt agatattaca aacacaatga taaatgatgt taaatctaat
      121 ctaacaatag atagtaacag tatagtagtg agaggtgagg tagttggata aagagattaa
      181 tctaataaat tacttaccac aaattctaca agataaagaa gaatatataa aagtatttaa
      241 tgtagaaaac aaagaaataa aaacactaca tgaaaaatta aatgacctat caagtgacca
      301 gtttttagag gatttaactc caagtggtat aaaaagatgg gaaaagataa tgtctataac
      361 tcctaaaagt aatgagagtt tagaagatag aaggtttagg atttttagta aatatataag
      421 taaactacct tactcagaga gatttttaag gaactggcta gatagtatag ttggagaagg
      481 caattatgaa ttaactatta ataatgctac ttataatata catcttgaaa gtgatgctag
      541 aaatcaagat tggtttgagg aggttcattc ttttgtaagt agtattaaac cttgcaacat
      601 gactttagat tacactagag tgcttgtaag taaagacaat tatatgaatt ttggtataac
      661 aaccctaata ggtcaagaaa taactatata cccttggagt ccaccagata tagaaactta
      721 tggagaaatt gatgtattaa ctggcaatgg agttggatac caagagataa caatatttta
      781 ggaggtgata tattggctat agataaaagt tattacacta taattacaga tgtagggaaa
      841 gcaaagatag caaatgcaag tgtcacaggt aataaagtgg gatttgtaaa aattcaactt
      901 ggtgatggag gagggagtga atatactcca actgagagtc agacagctct caaaaatgtg
      961 gtatgggaag gcaatatcgg aaatacaact acagatgaaa ctgcaccaaa ttgtataata
     1021 ttagagagtt taataccatc aagtgtaggc gggtttatga taagagaaat aggatattta
     1081 gatgatgaaa ataatttaat tgccatttct aaatacaaag agtgttataa accttctata
     1141 gaacaaggtg cagtggtaga catgaaggtt aaaactgtgc ttattgtatc taatgtaaat
     1201 aatatagaac ttaaaattga cccaacaata atctttgcaa cactcaaaga tatacaagac
     1261 ttagaaacta aaat
//
LOCUS       DAJMZY010000230         1270 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.237, whole genome shotgun sequence.
ACCESSION   DAJMZY010000230 DAJMZY010000000
VERSION     DAJMZY010000230.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1270)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1270)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1270
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.237"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            <1..1121
                     /locus_tag="OE968_003802"
     CDS             <1..1121
                     /locus_tag="OE968_003802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HCP7220991.1"
                     /translation="EEYKNKYFTGNKIVLSINSFDNKELYYHETENILNLINEIDKLT
                     SSKIFKTIEDKNDLALESYYSSVIEGAFSTRKIAKSIIRGKMKPSNKSEYMIYNNHRA
                     LEYGLDNLDKLYSHKFIYDLHHILGENCLDSEEYEYRTEKVYVCDSKGEIIHTGLEPL
                     KIYDFMSKLIDFMENSKVSNLIKSAIIHFYFVYVHPFSDGNGRTSRALSYLYLIDKGY
                     DTFKDFSISYMISKNRTKYYKAILDVENKGNNLTVFIEFMLKSIIQSINEMRNMHDRK
                     SLESILKEELFENDITLSATEEHILKYICNKDNYSMTLENYIKKNKSRYLKAGIKEIE
                     LVDQLMEVFNNLEEIEILSKEKNIYKVNDKYLKMLDID"
BASE COUNT          548 a          110 c          194 g          418 t
ORIGIN      
        1 tagaagaata caaaaacaaa tactttactg gaaataaaat cgtactttct ataaatagtt
       61 ttgataataa agaactatac tatcatgaaa ctgaaaatat attaaattta ataaatgaaa
      121 tagataaatt aacatcaagt aagatattta aaacaataga agataaaaat gatttggcac
      181 tagagtctta ttattctagt gtaatagaag gtgctttttc aactagaaag attgcaaaat
      241 ctataattag aggaaagatg aaaccaagta ataaaagtga atatatgatt tacaataatc
      301 atagagcctt agaatatgga ttagacaact tagataaatt atatagtcac aaatttatat
      361 atgatttgca tcatatattg ggcgaaaact gcttggattc agaagaatat gagtatagaa
      421 ctgaaaaagt atatgtatgt gattcaaaag gtgagattat acatacaggg cttgaacctt
      481 tgaagatata tgactttatg agtaaattaa tagattttat ggaaaatagc aaagtaagta
      541 atttaattaa aagtgctata attcattttt actttgtata tgttcatcct tttagtgatg
      601 gtaatggaag aacatcaaga gccttatcat atctatattt gattgataaa ggatatgata
      661 ctttcaagga tttttcaata tcatatatga tatctaaaaa cagaactaag tattataagg
      721 ctatacttga tgtagaaaac aaaggaaata atttaactgt atttatagaa tttatgctca
      781 agtctataat acaatctatt aatgagatgc gtaatatgca tgatagaaaa tctttagaaa
      841 gtatattaaa agaagaattg tttgaaaatg acataactct atcagcaaca gaagaacata
      901 tattaaaata tatttgcaat aaagataact attctatgac attagaaaat tatataaaaa
      961 agaataaaag tagatactta aaggctggaa taaaggaaat tgaattagtt gaccagttga
     1021 tggaagtgtt taataatctt gaagagatag agattttgtc taaagaaaaa aatatatata
     1081 aagttaatga taagtactta aaaatgcttg atatagacta atttagataa tctggagagg
     1141 gaatatatga ataataagaa aaaggcattt ttgatttctg gggctataaa cgtaatttca
     1201 ttaattattg ttttttcatt gtttcattat aatattatag aaaatagtac acaaaatatg
     1261 ataataactg
//
LOCUS       DAJMZY010000231         1247 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.238, whole genome shotgun sequence.
ACCESSION   DAJMZY010000231 DAJMZY010000000
VERSION     DAJMZY010000231.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1247)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1247)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1247
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.238"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            50..541
                     /locus_tag="OE968_003803"
     CDS             50..541
                     /locus_tag="OE968_003803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220992.1"
                     /translation="MYENNKVIYNLERCEKLEKTLYLSQFNTYKNFKLASKKTVINSL
                     ETYVYNMNINNISLVDTIECISLEDEQLTGKKLILVGDIDIDAILDYAGNKRNRNSSK
                     KNTFKLKIPFSTFIQMPRKIENKDKINLKYLIQDITSSILDDNLFISVTAIISYENSS
                     KIE"
     gene            569..>1247
                     /locus_tag="OE968_003804"
     CDS             569..>1247
                     /locus_tag="OE968_003804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220993.1"
                     /translation="MRITKTTFNDVFSSDANESIIKVEKYVDKKCASVFEILTYTIIV
                     TNTNRYKTGNIFFKDYISKYIEFINNTVKVNGIIKRGLDPQQGFYIGRIDASCKKIIS
                     FKSVVLPNSAHRIIKNSANIYYYYKCNLDKFPTRISIESNRVYTNVNKIVFKQLNISN
                     TLKAPKNLRDILKVNVNSKIFDVKPMKNLINKGSNLKLCNLIVFGCIEVEIDYSCKNR
                     SNFKTVNK"
BASE COUNT          548 a          102 c          178 g          419 t
ORIGIN      
        1 atttttatga atagtattaa tatatagata cagggagatt gatgcgatta tgtatgaaaa
       61 taataaggta atatacaacc ttgaaagatg tgaaaaacta gaaaagactc tttatttatc
      121 tcaatttaat acatataaaa attttaaatt agcttctaaa aaaactgtaa taaattcatt
      181 agagacatat gtttacaata tgaatattaa caatataagt cttgttgata ctatagaatg
      241 tatatcatta gaagatgaac aacttacagg aaagaagttg attttagttg gtgatataga
      301 tattgatgca atattagatt atgcaggaaa taaaagaaat agaaattcta gtaaaaaaaa
      361 tacatttaaa ttaaaaatac cctttagtac atttatacaa atgcctagaa agatagaaaa
      421 taaagataaa attaatttaa agtatcttat acaagatatt acttcatcta ttttagatga
      481 taatttattt attagtgtta ctgcaattat aagttatgaa aatagttcca agatagagta
      541 atctttaaat tatagaaagg tggatgcaat gagaataacg aaaactactt ttaatgatgt
      601 attttcaagt gatgcaaatg aaagtattat aaaagtagaa aaatatgttg ataaaaaatg
      661 tgcatctgta tttgagattt tgacctacac tattattgtt acaaatacaa ataggtacaa
      721 aactggaaat atatttttca aagattatat ttctaaatat atagagttta taaataatac
      781 tgtaaaagtt aatggcatta taaaacgtgg attagaccca cagcaaggtt tttacatagg
      841 gagaatagat gcaagttgta aaaaaataat atcttttaag agtgtagttt taccaaattc
      901 tgcacatagg attataaaga atagtgctaa tatatactat tattataagt gtaatctaga
      961 taaattccca acaagaatat caatagaaag taatagagtt tatactaatg taaataaaat
     1021 tgtattcaaa caattgaata taagtaatac tttaaaagct cctaaaaatc taagagatat
     1081 attaaaagta aatgtaaata gtaaaatatt tgatgttaaa cctatgaaaa atcttataaa
     1141 caaaggtagt aatttgaaat tatgtaactt gatagttttt gggtgtatag aagttgaaat
     1201 agactatagt tgtaaaaata ggagtaattt taaaacagta aataagt
//
LOCUS       DAJMZY010000232         1191 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.240, whole genome shotgun sequence.
ACCESSION   DAJMZY010000232 DAJMZY010000000
VERSION     DAJMZY010000232.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1191)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1191)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1191
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.240"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            67..798
                     /locus_tag="OE968_003805"
     CDS             67..798
                     /locus_tag="OE968_003805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220994.1"
                     /translation="MLSKKNVSLIILVIILSLLTAIFIFNNKNTNNKLKEVTKNNEEI
                     VPKNLEGLSIEQLIEIRDKAIDKNLEGLREFGEDSVKKRKDSILNFEFGLVAFVNKNY
                     SNLTEKEKLIRQINIVNYENSINDIMDPSGSFFELANQNYQVNEFLLKNGKDYKEWSY
                     EGLDFLIDHLEELCKFVDFDVKDVIDIIDPTIKTDLSEEQKKSLNDKLKKISSSDTLS
                     EEVKKEIKNWENNLNNLNMNKNNSN"
     gene            complement(955..1161)
                     /locus_tag="OE968_003806"
     CDS             complement(955..1161)
                     /locus_tag="OE968_003806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7220995.1"
                     /translation="MSKYSSLWEYFKKNNSQSFKLTFEEIKDIAGIEIDHSFLKYKKE
                     LNEYGYQVGKISLKEKTVIFDKIG"
BASE COUNT          497 a          127 c          147 g          420 t
ORIGIN      
        1 atgttatctt cataaacaaa tttatttttc acaagtacaa tacttattta aaaaaggagg
       61 tttaatatgt taagtaaaaa aaatgtaagt ttaattattt tagtaataat tttaagttta
      121 ttaactgcta tatttatttt caataataaa aatactaaca ataaattgaa agaagttact
      181 aagaataatg aagaaatagt acctaaaaac ttagaaggtt taagtataga acaattaata
      241 gagattagag ataaagccat tgataaaaat ttagaaggtc ttagggaatt tggagaagat
      301 tcagtaaaaa aacgtaaaga ttcaatttta aactttgaat ttggattagt agcttttgtt
      361 aacaagaatt atagcaactt aacagaaaaa gagaaattaa taagacaaat taatattgtt
      421 aactatgaaa actctataaa tgatataatg gatccttcag gttcattctt tgaattagca
      481 aatcagaatt accaagtgaa tgagtttcta ttaaaaaacg gaaaagatta taaagaatgg
      541 tcatatgaag gtctagattt tctaattgat catctagaag aactgtgcaa atttgttgat
      601 tttgatgtaa aagatgtaat agatattatt gatcctacaa taaaaacaga cctttcagag
      661 gaacaaaaga aatctttgaa tgataaatta aagaaaatat cttcaagtga tactttaagt
      721 gaagaagtta aaaaggagat aaaaaactgg gaaaacaatt taaataattt aaatatgaat
      781 aaaaataatt ctaattaatt ttctcataag aaaaatgctt atatcgtgat aatgtgaaat
      841 gtacataatt ataaacaaaa aaggggctgt gacactaaaa aatagtgcta cgcccttttt
      901 tatttgtaat aatcatcaat acaaattatt ttattatatg taattattta tgtcttaacc
      961 aattttatcg aaaataacag tcttctcttt taaagagatt tttcctactt gatatccata
     1021 ttcatttaat tcctttttat atttcaaaaa cgaatggtct atctctatcc cagcaatatc
     1081 ttttatttct tcaaaagtta atttaaacga ttgactattg tttttcttaa aatattccca
     1141 taaagaacta tatttactca tcttatatca ctccttttaa aatcatatct t
//
LOCUS       DAJMZY010000233         1155 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.241, whole genome shotgun sequence.
ACCESSION   DAJMZY010000233 DAJMZY010000000
VERSION     DAJMZY010000233.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1155)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1155)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1155
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.241"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            complement(431..898)
                     /locus_tag="OE968_003807"
     CDS             complement(431..898)
                     /locus_tag="OE968_003807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HCP7220996.1"
                     /translation="MKFLNVLIVVEDIEKSKKFYYDVLGLKVICDFGENVVLEGNISL
                     QEKKLWLEFINKSDSEVKFNGNDAELYFEEDYFDTFVERLSTMRDIDYVHLAIEHRWG
                     QRAIRFYDLDGHIIEVGETMSSVCRRFLDSGLSIDEVAKRMDVTVEYIESVLE"
BASE COUNT          447 a          185 c           74 g          449 t
ORIGIN      
        1 attttttgtc tttaagaaca ataataatat tattatttat gtttcttatt taaacattat
       61 tttatttgaa atatttatta aataaataaa ctaaaactac aattttcact atatttttaa
      121 tttgttcaat taaattttaa cataattaca taaaatagta tatatgattc tacagcttga
      181 tagtaagtat aattatcttt tataagctaa tacttatatt tttctaaatt taaatcatcc
      241 aataaatatt aaattctatt ataatatgta aggaaaatca tgcacttttt aaaaatccaa
      301 ataaaattat aacaaatatt atattctgta tcttacaaaa acaaaaactg taagtaaatt
      361 tgtttccata caagtttact tacagccctt acttctatac aaaatatagt tttactttaa
      421 tataatccat ctattctaaa actgattcaa tatattcgac agttacatcc attcttttag
      481 ctacctcatc tattgaaaga ccactatcta aaaaacgtct acacacagat gacatagttt
      541 ctccaacctc aataatatgc ccatctaaat cataaaatct aattgctctt tgaccccacc
      601 tatgctctat agctagatga acataatcta tatctctcat tgtactcaat ctttcaacaa
      661 aagtatcaaa ataatcttcc tcaaaataca gctcagcatc atttccattg aacttaactt
      721 cactgtcact cttattaata aactctaacc aaagcttttt ttcttgtaat gatatattcc
      781 cttctaatac aacattttct ccaaaatcac agattacctt taaccccaaa acatcataat
      841 aaaacttttt tgatttctca atatcttcaa ctactattaa aacatttaaa aacttcatat
      901 tacctcctta atatacacat actttattta taatatataa ttagaattaa actataaagg
      961 tttcaataag gtctagtata aagaaaaaaa ttataagtct tattgaaata gttaagttaa
     1021 ttgtatcata taatataaat tttaatcttg taaaaaacag acacattcat acttttaggt
     1081 ttaaatctat atgtattctt attaattttg ctaaaactgt tatttttgta gactatttta
     1141 gattactgaa atatc
//
LOCUS       DAJMZY010000234         1144 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.242, whole genome shotgun sequence.
ACCESSION   DAJMZY010000234 DAJMZY010000000
VERSION     DAJMZY010000234.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1144)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1144)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1144
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.242"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            complement(686..1126)
                     /locus_tag="OE968_003808"
     CDS             complement(686..1126)
                     /locus_tag="OE968_003808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SufBD protein"
                     /protein_id="HCP7220997.1"
                     /translation="MKNLNLLINKLYSKNHNEAYKTFLFLENESLKSNITYCFFDSFL
                     EMIDNENSYIRTRGLLLISANAQWDIDNKIEINIDSILSHIVDKKPSVSRMFIKSIPN
                     ITKYKENLINRIKMELSNADISIYNNNMKPLVEKDINDTLSNIS"
BASE COUNT          406 a          144 c           81 g          513 t
ORIGIN      
        1 tgttatagca tcagcaattt ctttcatttt tattcccacc tttgctttta tgtaaaactc
       61 aatatattat ataatttaat ttatataatt taatttatat aatttaatat attattttca
      121 ttaattatat acctcaataa atttctataa aaatagtatc attttagtat catcatttat
      181 ttaatacatt atgtattccg tttagattta gttatccgaa aacttagata actagcttga
      241 aatttctaca gattattaca tactttattg taattatatc ataatgttat aattacatat
      301 tatcaaatta cacactatct tttattcata tagatattat catccttgtg tatatattgt
      361 caaagaaaac atttaattta caacatattt tatatcatat catctaaact attatataca
      421 ccttatctaa ttcacacatt aacactattg tactttttct aaaaattttt aaataaaaat
      481 gacagcttta atttattatt ttaaaactgc cattaaactg taaatattcc cttttagtat
      541 acaaaatttt acctttatgt taatatattt tacttatata aatttttcat aattaattta
      601 tacatataaa ttagcaccat tgttgtttta ttatcttagt tataaataat tgtaactaga
      661 taatattcaa tttctatatt aatatttaac taatattaga taatgtatcg tttatatcct
      721 tttctactaa tggtttcata ttattattat aaatacttat atctgcatta cttaattcca
      781 tttttatgcg attaataaga ttttctttat actttgtaat attaggtatg gatttaataa
      841 acattcttga tacagaaggt tttttatcta cgatatgact tagtatacta tctatattta
      901 tttcaatttt attatcaata tcccactgag catttgcaga gattaataac aatccccttg
      961 ttcgaatata tgagttttcg ttatcaatca tttctaggaa tgagtcaaaa aaacaatatg
     1021 taatatttga ttttaaactt tcattttcta agaataaaaa agttttatat gcttcattat
     1081 gattttttga atataattta ttaataagta aattgagatt cttcaatctt ctcatctccc
     1141 tcat
//
LOCUS       DAJMZY010000235         1115 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.243, whole genome shotgun sequence.
ACCESSION   DAJMZY010000235 DAJMZY010000000
VERSION     DAJMZY010000235.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1115)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1115)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1115
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.243"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            256..957
                     /locus_tag="OE968_003809"
     CDS             256..957
                     /locus_tag="OE968_003809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4253 domain-containing protein"
                     /protein_id="HCP7220998.1"
                     /translation="MSIEDLYDFECVPLNNEIDIDVLFEKMIEDGKEKEYTPIIVIDE
                     KVGLLRKNIDMITKEYGSLENYREYCLTKYNEIDVNQFFDFRKSEISELLKELIDLED
                     DFYDYKHFRPIMNIDIFHEYNKVYIAKIPTIKPYEVFAYIPIGGFNDCPRDEEHIAIA
                     KYWYEKHGIFPIAIGCDTVQYSVKNLTKDGKKFDDLCIELVFYCEDIIIQGYETLKAL
                     KDVLKRSTIVLFWWD"
BASE COUNT          440 a           99 c          174 g          402 t
ORIGIN      
        1 acgaattgtt acaaaattac ttattattaa ccatgaacat ttgttttgtg ctatcatatt
       61 tatataaggg aattgtcata aaaaatatct tgttcataca gttttatata gaaaaaagaa
      121 atgaatcttt tctttatata agtatatttt gtaaattgcc tctatattta tagtttaaat
      181 aatagtggta ttaaaaatct gacaacaaaa ataaaacttt caaaaaatta aatctaaaaa
      241 gaataggaga taaatatgag tattgaagat ttatatgatt ttgaatgtgt tcctttgaac
      301 aatgagattg atattgatgt tttatttgaa aagatgatag aagatggaaa agaaaaagaa
      361 tatacaccaa ttatagtcat tgatgaaaaa gtagggctat taagaaaaaa tatagatatg
      421 attactaaag agtatggttc tcttgaaaac tatagagagt attgtttaac aaaatataat
      481 gaaattgatg taaatcaatt ttttgatttt aggaagagtg agatttcaga attattaaag
      541 gagctaattg atttagaaga tgatttttat gattataaac attttagacc cattatgaat
      601 atagatatat ttcatgaata taacaaagtt tacatagcta aaattccaac aattaaacca
      661 tatgaagtat ttgcatacat acctattggc ggatttaatg attgtcctag agatgaagaa
      721 catatagcta ttgcaaaata ttggtatgaa aagcatggaa tctttccaat cgcaattgga
      781 tgtgatacag ttcaatattc tgtaaaaaat ttaactaaag atggtaaaaa atttgatgac
      841 ttatgtattg aattagtatt ttattgtgag gatattatta tacaagggta tgaaacctta
      901 aaggctctta aggatgtatt aaaacgctct acaatagtgc ttttttggtg ggattgatat
      961 tctatcattt agatagtatt aaattgttag tcaccaagaa tccacttgct ttagttatag
     1021 ggagtgtgtc aaactaggtt tttatacaca gtgtagcata gtaatatgtt taaattacaa
     1081 aggttaaaaa aatactttaa tatttttaat attat
//
LOCUS       DAJMZY010000236         1098 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.245, whole genome shotgun sequence.
ACCESSION   DAJMZY010000236 DAJMZY010000000
VERSION     DAJMZY010000236.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1098)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1098)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1098
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.245"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            complement(225..971)
                     /gene="cdtR"
                     /locus_tag="OE968_003810"
     CDS             complement(225..971)
                     /gene="cdtR"
                     /locus_tag="OE968_003810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family response regulator CdtR"
                     /protein_id="HCP7220999.1"
                     /translation="MDILIFDNDVCFGMKLKEKINNILIKEGFDNDVVRLYHNANLLL
                     KELTEKNKVRIYFIVVDAKYKISNELCDGLWIAQKIRESDYISPIIFLTNHIEMILGI
                     FDYRLEVMDFILKHDMEIAESKIKACIKIAHKRYIKEKNYRSNFFTIYSDFSLWKISF
                     DEVIYFETSTIPHKIKLVTTSRIFEFYKSLKSLPDLDACFIRVHKSFVVNKYHIVSLD
                     LKKNNIKMSNGHICRISNTYRNILKNIIKT"
BASE COUNT          401 a          135 c          115 g          447 t
ORIGIN      
        1 ttttaaagag actatttcgt acttttatga tttaatgagc tatcttatcg aatcataatc
       61 taggaacaat tgttataata tctaatagta gttatatatg atatagtcag tatgtgtttt
      121 ttcacaatat gattattata tagaggattc ttagggatta ctctttttgt ataaaaaaga
      181 gatggttcaa atttttatct tgagacatct cctttttcta tttattatgt tttaataata
      241 ttctttaaaa tatttctata tgtattagat atacgacata tatggccatt actcatttta
      301 atattatttt tctttaggtc gagagaaaca atatgatatt tattaactac aaaagattta
      361 tgtacacgga taaagcatgc atctaaatct ggtaaagact ttaaactttt atagaattca
      421 aatattctag aagtagtcac taattttatt ttatgtggaa tagtgcttgt ttcaaaatat
      481 ataacttcat caaatgaaat tttccatagt gagaaatctg aatagatagt aaaaaaatta
      541 gagcgataat ttttttcttt aatgtatctt ttgtgagcaa ttttaataca agcttttatt
      601 ttactttcag caatttccat atcatgtttt agtataaagt ccataacttc taacctataa
      661 tcgaagatcc ctaaaatcat ttctatatga tttgtaagaa atatgattgg actaatataa
      721 tctgattctc taattttttg tgctatccat aatccatcac ataattcatt acttatctta
      781 tattttgcgt ctacaactat aaaatatatt cttactttat ttttttcagt aagctctttt
      841 aataacaaat ttgcattatg atataatctt acaacatcat tatcaaaacc ttcttttatt
      901 aaaatattat ttattttttc ttttagtttc attccaaaac aaacatcatt atcaaagatt
      961 aatatatcca ctaaataccc tcctataaaa aattcaaaag taaaaaaaca aaagtatttt
     1021 atagaaaata cataaaataa cactaggaga taaataagat taaggatagt tagaattaag
     1081 gtatatttat gcttgttt
//
LOCUS       DAJMZY010000237         1076 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.246, whole genome shotgun sequence.
ACCESSION   DAJMZY010000237 DAJMZY010000000
VERSION     DAJMZY010000237.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1076)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1076)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1076
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.246"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            complement(211..>1076)
                     /locus_tag="OE968_003811"
     CDS             complement(211..>1076)
                     /locus_tag="OE968_003811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011988116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_except=(pos:complement(469..471),aa:Sec)
                     /transl_table=11
                     /product="glycine/betaine/sarcosine/D-proline family
                     reductase selenoprotein B"
                     /protein_id="HCP7221000.1"
                     /translation="PIMTKLGLKLVRGEEIGPPEEEGYIMRGIRKNFFHELRGSERAI
                     DMLVKKMKGESFETEYPMPEFDRVTPMKPVKDLSKIKLALVTSGGIVPIDNPDKIESS
                     SATKYGIYDLTDMDSMSNKEFTTIHGGYDRAYVLENPNLVVPLDVVRELEKEGVIGEL
                     VDYFITTTGTGTSVGNSKRFGEEFSKKLLEDDVDAVILTSTUGTCTRCGATMVKEIER
                     AGIAVVHICTVVPISLTIGANRIVPAVGIPYPLGNPMLGEEESKKIRKNIVLKALNAL
                     TEDIEEQTVFE"
BASE COUNT          325 a          204 c          119 g          428 t
ORIGIN      
        1 gttccaaaat gtaataatct cgcttttcat agtatatcta atttgaattt gtgtatcaat
       61 attataataa actaatttat cacttttata aatttaattt taaaaaatgc aaatttcgaa
      121 tttacctaat aaaaaaaaga tatcgtaaaa taattttaaa aaattatttt ttgatatctt
      181 tttttatttc agtgttgtgt tgtattttta ttattcaaat actgtttgtt cttctatatc
      241 ttctgttagt gcatttaaag cttttaaaac tatattcttt ctaatttttt tactttcctc
      301 ttctcctaac ataggatttc caagtggata tggtatccct actgctggaa caattctatt
      361 agctcctatt gtaagtgata ttggtactac tgtacatata tgaacaactg ctataccagc
      421 tctctcaatc tcttttacca tcgttgctcc acaacgagta caagtacctc atgtagaagt
      481 taaaattaca gcatctacat catcttctaa caatttttta gaaaactctt ctccaaatct
      541 cttagaattg ccaacactcg ttcctgttcc tgtagtagtt ataaaataat ctactaattc
      601 tccaattaca ccttcttttt caagctctct aactacatct agtggtacaa ctaaatttgg
      661 attttcaagg acatatgctc tgtcataccc cccatgtata gttgtaaatt ctttatttga
      721 catagaatcc atatctgtta aatcgtaaat tccatattta gtagcacttg aagattcaat
      781 tttgtctgga ttatcaattg gaactatccc tccagaagtt actagggcaa gttttatctt
      841 agataaatct ttaacaggtt tcataggtgt aactctatca aattcaggca ttggatactc
      901 agtttcaaag ctttcccctt tcatcttttt aaccaacata tcaattgctc tttcagaccc
      961 tctaagttca tggaagaaat tttttcttat tcctctcatt atatatcctt cctcttcagg
     1021 aggtcctatt tcctcacctc taaccaattt aagacctagt tttgtcatta ttggaa
//
LOCUS       DAJMZY010000238         1068 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.247, whole genome shotgun sequence.
ACCESSION   DAJMZY010000238 DAJMZY010000000
VERSION     DAJMZY010000238.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1068)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1068)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1068
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.247"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            285..578
                     /locus_tag="OE968_003812"
     CDS             285..578
                     /locus_tag="OE968_003812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HCP7221001.1"
                     /translation="MGFPETFKALSDPIRREILVMLRENKMSAGEISEKFNMTNATIS
                     YHLSQLKKAGLIFETKYKNFIFYEINISVFEEVMLWFSQFMEKGEKDNEKSDK"
     gene            559..>1068
                     /locus_tag="OE968_003813"
     CDS             559..>1068
                     /locus_tag="OE968_003813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1648 domain-containing protein"
                     /protein_id="HCP7221002.1"
                     /translation="MKKAINKQFILSTLICFIPFIVSIYFYNRLPNEVAIHFDNYGNP
                     DNYAPKVIAAFGVPLLMLCIHLYTWFRLENEPKKANFSNVIQNLSKWGVAILSVIIQI
                     MMVLYSTGVSLESNFYTGLILGIIVILFGNYLPKCKRNYSVGIILPWTLNDEDNWNKT
                     HHLAGWIWLI"
BASE COUNT          404 a          108 c          171 g          385 t
ORIGIN      
        1 tacttttaat ttaaaattaa aagtattgtt atatatataa gtacctcagt cattaggttt
       61 ttgctttaac aattatggtg caatacactt ttgttaagtt aaaaaaatta gataaagtaa
      121 gattaaataa aagcgactta agtaaattga gaatcttaat atgaaaattt tcaataaata
      181 tttagaaata actatttaga aaaaattcta aatagttatt gaaataaaat ggatgttatg
      241 ttatattcta tttagatgaa attctaaata gcgaggtgat ggtgttgggg tttccagaaa
      301 cattcaaagc tctttcagac cctataagaa gagaaatatt ggttatgttg agggagaata
      361 aaatgtcagc aggagaaatt agtgaaaaat ttaatatgac gaatgctaca atttcttatc
      421 atctatctca actaaaaaag gcaggactca tatttgaaac aaagtataag aactttattt
      481 tctacgaaat aaatatttca gttttcgaag aggttatgct ttggttttcg caatttatgg
      541 agaagggaga aaaagataat gaaaaaagcg ataaataaac aatttatttt atctacttta
      601 atatgtttta taccatttat tgtatcaata tatttttata atagattacc aaatgaagtt
      661 gcaattcatt ttgataatta tggaaatcca gataattatg ctccaaaggt tatagcagct
      721 tttggtgtac cattgttaat gctatgtatc catttgtata catggtttag acttgagaat
      781 gagcctaaga aagctaattt ttcaaatgtt atacaaaatt tatcaaaatg gggagttgct
      841 atactttcag taattataca aataatgatg gttttatatt caacaggagt tagtttggag
      901 tctaattttt atacaggatt aattttagga ataatagtta ttttatttgg aaactatctt
      961 cctaaatgta aacgaaatta ctcagtagga ataattttac catggactct taatgatgaa
     1021 gataattgga ataagacaca ccatttagct ggatggattt ggcttatt
//
LOCUS       DAJMZY010000239         1041 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.248, whole genome shotgun sequence.
ACCESSION   DAJMZY010000239 DAJMZY010000000
VERSION     DAJMZY010000239.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1041)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1041)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1041
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.248"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            223..600
                     /locus_tag="OE968_003814"
     CDS             223..600
                     /locus_tag="OE968_003814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HCP7221003.1"
                     /translation="MKEEILIEKLLRVELIVMEYLWKKDTLMPKKKIVKEIKQIYGWH
                     KSTIKILLKRLVDKRYLARYIINFQSYYKIIIDNKEYYTFKKKVLKSSKSIKIMHSLT
                     TIHKNVSKEKLDLLDEYYRNLKE"
     gene            705..1041
                     /locus_tag="OE968_003815"
                     /pseudo
     CDS             705..1041
                     /locus_tag="OE968_003815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430377.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
BASE COUNT          476 a           86 c          153 g          326 t
ORIGIN      
        1 tagcgattta gtgctattct acaactaaaa taatacaata gagctattta ttgtttggta
       61 gcattgtttg caaattaaac aaatttatat atatgaatat tattttacgt ttaaaaaaac
      121 agactaaata tgtagaatat ttggtaaaac ttacctctag tttttgtctt aaaaagctcc
      181 tattattaat ttaagttaga agaattaagg aagtgacata aattgaaaga agaaatatta
      241 atagaaaaat tattaagagt agaattaata gtaatggagt atttatggaa aaaagacact
      301 ctaatgccta aaaaaaaaat tgtaaaagaa ataaaacaga tttatggatg gcataaaagt
      361 acaataaaaa tactactaaa aaggctagtt gataaaaggt atttggctag atatattata
      421 aattttcaat cttattataa aataataata gataataaag aatattatac ttttaagaaa
      481 aaggtactaa aatctagtaa aagcataaaa ataatgcatt cacttaccac tatacataaa
      541 aatgtaagta aagagaagtt agacctatta gatgagtatt atagaaactt aaaagaatga
      601 tatagtaaaa atcgaatgta attatttacc ttaattcctt tgtttgtaaa actttattga
      661 tatagaattt gacatataca taaattggta aagggatgta tactatgaaa attagtaaat
      721 taccagaagc ggaattaaaa gttatgagat atatttggga atcagaaaag gtattaatac
      781 caagagaaat caccaagtct atggaacaaa aatatgaatg gaaagataca actatattta
      841 cagtattaaa aagattacta aagaagagag tttttagaag cggagaaaat agataagtgt
      901 acacactata atgtattagt aaaaaaaaat aatatcagag attttaaaca aaagaatttt
      961 taaagaatac acataaaaat tcaatattaa gtttaatgtc agcactatgt agtaaggatg
     1021 atgaagtaga tggtgatatt t
//
LOCUS       DAJMZY010000240         1014 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.249, whole genome shotgun sequence.
ACCESSION   DAJMZY010000240 DAJMZY010000000
VERSION     DAJMZY010000240.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1014)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1014)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1014
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.249"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            344..676
                     /locus_tag="OE968_003816"
     CDS             344..676
                     /locus_tag="OE968_003816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HCP7221004.1"
                     /translation="MNTREMKEYRGFYNKKLSETDEFFRVFGSLDDKTYSEGAISKKN
                     KELMGLAISILSRCDECICYHIEGCINSGASKDEIIEAIKIGVIGGGSITYPNARFAI
                     KILEEFNI"
BASE COUNT          404 a           75 c          144 g          391 t
ORIGIN      
        1 taatattcct ttttataata tctttgtaat ctttgtaatt gtaatactac catttgtata
       61 ttcttatttg atgtataaaa tttcaggtaa aaataactaa tataattaat cactataata
      121 atgtttggat aagaataata tatttcagaa ctgagataga taataaagaa attactgaga
      181 tttctatttt agttctgaaa aaatcttact tatatgataa cttattgaga tttcaaaaaa
      241 taatataaat taggctaatg aacataaaat gaaaatttgt atttaatatt gaaaatataa
      301 gtacagtgtg atactcttat aagaaaaaaa taggaggtag aagatgaata ctagagaaat
      361 gaaagaatat aggggatttt acaataaaaa attaagtgaa acagatgagt tttttagagt
      421 atttggaagc cttgatgata agacttattc agaaggggct ataagtaaaa aaaataagga
      481 attaatggga ctagctattt caattttaag ccgatgtgat gagtgtattt gttatcatat
      541 tgagggttgt attaattctg gagcaagtaa agatgaaatt atagaagcta taaaaatagg
      601 tgtaattggt ggagggtcta ttacatatcc aaacgcaaga tttgcaataa aaattttaga
      661 agaatttaat atataatttt gatacacgta gtttatttag actaataata atagtctatt
      721 taagcctttg aaattaagct ttattttcta agttcacttc ttattaagtt tttagaattg
      781 catatataaa tataaatttt taaataatat agtagtttta aattatttac atcatagatt
      841 gtattgagaa tagtatattg tcattattaa atcttttata cattttttat tttaaataaa
      901 ttgaatatta aggtgattat atttacatat ttgtattttt atgaactaga atattcttta
      961 taaattcata gcagttttaa tagataactt tttcagatag attaaacaaa gttt
//
LOCUS       DAJMZY010000241         1013 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.250, whole genome shotgun sequence.
ACCESSION   DAJMZY010000241 DAJMZY010000000
VERSION     DAJMZY010000241.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1013)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1013)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1013
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.250"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            <1..513
                     /locus_tag="OE968_003817"
     CDS             <1..513
                     /locus_tag="OE968_003817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7221005.1"
                     /translation="NLLYKKDDSLKVNRYFVVENNKYKLLLYESFKKEFGINSMDLAQ
                     LKLNDFGLKYFKEVDLILKKAIAINPTDSKLYYAQACNYMNFDGFPGYSDTTYNALDS
                     INKSLKYLDKNDSDYKKNASNIYNLKGVILMFHKRFDEAQQYLNKALYFNKDNKDPKY
                     NLNTIKKHLN"
     gene            complement(737..901)
                     /locus_tag="OE968_003818"
     CDS             complement(737..901)
                     /locus_tag="OE968_003818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7221006.1"
                     /translation="MFGKPKESVRFLDFNDVAEKFGEKKAVAIFDAIAGKKSKEHIIK
                     DIEKLVKNEV"
BASE COUNT          401 a          142 c           89 g          381 t
ORIGIN      
        1 aaccttcttt ataaaaaaga tgattctcta aaagtaaata gatattttgt agttgaaaat
       61 aacaaataca agctattatt gtatgaaagt ttcaaaaaag aatttggtat taatagtatg
      121 gaccttgctc aacttaagct taatgatttt ggactaaaat actttaaaga agttgacctt
      181 atactaaaaa aagctattgc tattaatcct actgattcaa agctttatta tgcccaagca
      241 tgtaattata tgaattttga tggatttcct ggttattcag atacaacata taatgcttta
      301 gattcaatta ataaatcttt aaagtattta gataaaaatg attctgacta caaaaaaaat
      361 gcaagtaata tatataactt aaaaggagtt attcttatgt ttcacaaaag atttgatgaa
      421 gcacaacaat atttaaataa agccttatac tttaacaaag ataataaaga cccaaaatat
      481 aatctaaata caataaaaaa acatctaaac tagatattta atttttgaat ttataaaata
      541 tttttttatg tataattcag cactgaatca taatctctac taaactaatt acaagtttaa
      601 attataaaga cttatttcta tataaatatt actctataac aataagtttc ttatttaaat
      661 tttaaaatat tatctaaaaa tcataaaaaa gaaggtataa agagctaccc tcaagctcaa
      721 tataccttat aaatatctaa acttcatttt ttactaattt ttctatatct ttgataatat
      781 gttctttaga tttttttcca gctatggcat caaaaattgc aacagccttt ttctctccaa
      841 acttttctgc tacatcatta aagtctaaaa atctaacact ttcttttggt ttaccaaaca
      901 tataacacct ctcatacatt tttatatatt tattataact tctatagact tatttttcac
      961 caataaacgt tagacaaatt agtcccttta tttttttaaa ctagctttac ctt
//
LOCUS       DAJMZY010000242          983 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.252, whole genome shotgun sequence.
ACCESSION   DAJMZY010000242 DAJMZY010000000
VERSION     DAJMZY010000242.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 983)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 983)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..983
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.252"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            57..311
                     /locus_tag="OE968_003819"
     CDS             57..311
                     /locus_tag="OE968_003819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7221007.1"
                     /translation="MENKDFKLTICIFAFVIGVVVLFCCIGLGEFSAEHIIQQNGGIM
                     DTDQYNIYLDQSISQYRNFGSILALLGGIGILFDKYIRKY"
     gene            356..679
                     /locus_tag="OE968_003820"
     CDS             356..679
                     /locus_tag="OE968_003820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7221008.1"
                     /translation="MATEIFTVKITPLEAQKMIKENLDADLVFSDSYNLGDDKFILIT
                     TFEKYYARNNSDAGLIVVYENTTGKTVIKATSTGSAIGILKIDWGAGGNLLKRVKNIL
                     ADYII"
BASE COUNT          408 a           78 c          156 g          341 t
ORIGIN      
        1 taatataaaa tctagtaaaa ataatcaaat aaatttagct tatgagaggg ataactatgg
       61 aaaataagga ttttaaatta acaatatgta tatttgcttt tgtaattgga gtagtagtat
      121 tattctgttg tataggttta ggtgaattta gtgcagagca tattattcaa caaaatggtg
      181 gaatcatgga tactgaccaa tataatattt atctagacca atctatttct caatatagaa
      241 attttggttc tatattagct ctgttaggag gaatagggat attgtttgat aaatatatca
      301 gaaaatacta gagattatgt tttgtctaaa ataaattctt atgaggagat aaaaaatggc
      361 aacagaaata tttactgtaa aaattacacc cttagaggca caaaaaatga taaaagaaaa
      421 tcttgatgca gatttagttt ttagtgattc ttataattta ggagatgata aatttatact
      481 aattacaact tttgagaagt attatgcaag aaataatagt gatgcaggat taatagtagt
      541 ttatgaaaat accacaggaa aaacagttat taaagctact tcaacaggca gtgcaattgg
      601 aattttaaaa attgattggg gtgcaggtgg aaatttactt aaaagagtaa aaaacatact
      661 tgctgattat attatttaat tattttatct aactgataat atgtcaagaa aatctcgtaa
      721 aagaggttaa gaacattttt ataatatata gataaataag aatttgaagg taaagttttt
      781 aaggtataaa gaaaaataat ataataaaac gaattggctt tataattctt tataaggcaa
      841 agagcacatt tctttatata attgttggat attaaataat atgtaaatac accatttaca
      901 tataaaaatt taattaatat gttaagagaa aatgaaatgg aaattactaa aaaatatttt
      961 taaattggat aatggttgat att
//
LOCUS       DAJMZY010000243          960 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.253, whole genome shotgun sequence.
ACCESSION   DAJMZY010000243 DAJMZY010000000
VERSION     DAJMZY010000243.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 960)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 960)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..960
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.253"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            complement(<1..>960)
                     /locus_tag="OE968_003821"
     CDS             complement(<1..>960)
                     /locus_tag="OE968_003821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="PAS domain-containing sensor histidine kinase"
                     /protein_id="HCP7221009.1"
                     /translation="EFINILKVGCLVLVFVSILGVVNLKIQKFQIVLLNLSIINMSTF
                     IYLTISKVKKLRISPILIFYSAFVILDYFIRNIFSDINWNMIIILINVCISMFNLLYL
                     LNKLDSNIEHYKLIKDLTYFVFFTTIICFVAISKINIVDSDRLIGVIYLLLCNHTYYV
                     YVYSLNNRVVYPYYELDSINKKLSKKSEQLGKINLAIEKDMIIQRTLKNYIDQRKELL
                     RQALDTIPNVWIVTDYDFNISYTNNKFKDEFSKDMNNYYKILTFIKEDEKVAEKLKKF
                     DNDISIIDKLVELNDKIYLLSLSNNKDESNYLISLNDITNEIK"
BASE COUNT          352 a          126 c           73 g          409 t
ORIGIN      
        1 attttgattt catttgtaat atcatttaaa cttattaagt aattgctttc atctttatta
       61 ttacttaaac ttaacaaata aattttatca tttaactcta ccagtttatc aattatactt
      121 atatcgttat caaatttctt caatttttca gcaacttttt catcttcctt tataaaagtt
      181 aatattttat aataattatt catatccttt gaaaattcat ctttaaattt attatttgtg
      241 taacttatat taaaatcata gtctgttact atccatacat ttggtattgt atccagagct
      301 tgtctaagta attcttttct ctggtctatg tagtttttta atgttctttg tataatcata
      361 tccttttcta ttgctaaatt tatctttcct aattgctctg actttttact taatttttta
      421 ttgattgaat caagttcata atatggatac actactctat tattaagact gtatacatat
      481 acataataag tatggttaca taatagtaaa tatattactc ctattaatct atctgaatct
      541 actatattaa tcttagaaat tgctacaaaa catataatag ttgtaaaaaa aacaaaatat
      601 gttaaatctt ttattaactt atagtgctca atgttactat caagtttatt caacaaatat
      661 agtaaattaa acatagatat acaaacatta attaatataa taatcatatt ccagttaata
      721 tcactaaaaa tatttcttat aaagtaatct aatatcacaa aagcactata aaaaattagt
      781 attgggctta ttcttagttt ttttacttta gaaatggtta agtatataaa agtagacata
      841 ttaattatgc ttaagttaag caatacaatt tggaattttt gaatttttaa atttactact
      901 cctaaaatac ttacaaaaac taatacaaga caccctactt tcaatatatt tataaattca
//
LOCUS       DAJMZY010000244          918 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.254, whole genome shotgun sequence.
ACCESSION   DAJMZY010000244 DAJMZY010000000
VERSION     DAJMZY010000244.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 918)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 918)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..918
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.254"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            <1..744
                     /locus_tag="OE968_003822"
     CDS             <1..744
                     /locus_tag="OE968_003822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HCP7221010.1"
                     /translation="LNTNKKLLEKSKNAKNYNYVKLAYKSIYLCFEKIQNYEMSMKYF
                     KMYYELKMMYIKARNRNYIDSLNYRHEYIEKEINNMRKVKLDLDKKKYVDHLTSAYNR
                     TFLNDFLEKQEVSEYCTAFMIDVDYFKEYNDTYGHYNGDIALKNITIIIKKYLKKDML
                     MIRYGGEEFLILSVCKDYKKSKIFGRKLCRIVKKFLNNNLTVSIGIDTCKNSSIDIKE
                     IIENADKALYKAKESGRNRCLHYHDFKNF"
     gene            771..>918
                     /locus_tag="OE968_003823"
     CDS             771..>918
                     /locus_tag="OE968_003823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7221011.1"
                     /translation="MKRSLIEDLKRNINKIEYDMLTKFYLNLTDLNYILDYHKDLLNT
                     KLEDN"
BASE COUNT          418 a           66 c          141 g          293 t
ORIGIN      
        1 ttaaacacaa ataaaaaact ccttgaaaaa tctaaaaatg ctaaaaatta taattatgtg
       61 aagttagcat acaagagtat atatttgtgt tttgaaaaga ttcaaaatta tgaaatgagt
      121 atgaaatact ttaaaatgta ttatgagtta aaaatgatgt atataaaagc tcgaaataga
      181 aattatatag attccttaaa ttatagacat gagtatatag aaaaagaaat aaataacatg
      241 agaaaagtaa aacttgattt agataaaaaa aagtatgttg accatttgac aagtgcatat
      301 aatagaactt ttttgaacga ttttttagaa aaacaagaag ttagtgaata ttgcacagca
      361 tttatgatag atgtagatta ctttaaagaa tacaatgata cttatggaca ctataatgga
      421 gatattgctc ttaaaaatat aactataata ataaaaaaat atctaaaaaa agacatgctt
      481 atgataaggt atggtggaga agaatttctg atattatctg tatgtaaaga ttataaaaaa
      541 agtaaaatat ttggaagaaa attatgtagg attgtaaaga aatttttaaa caataatttg
      601 acagttagta ttggcattga tacatgtaaa aatagtagta tagatataaa agaaataatt
      661 gaaaatgctg ataaagcttt atataaagca aaggaaagtg gtagaaatag atgtttgcat
      721 tatcatgatt ttaagaattt ttaactgttg aaataggatt ggtgatttac ttgaaaagga
      781 gtttaataga agatttaaag agaaatataa acaagataga atacgatatg ttgactaaat
      841 tctatctaaa tttgacagat ttaaactaca tcttggatta tcacaaagac cttttaaata
      901 caaaattaga agataata
//
LOCUS       DAJMZY010000245          915 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.255, whole genome shotgun sequence.
ACCESSION   DAJMZY010000245 DAJMZY010000000
VERSION     DAJMZY010000245.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 915)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 915)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..915
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.255"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            118..816
                     /locus_tag="OE968_003824"
     CDS             118..816
                     /locus_tag="OE968_003824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HCP7221012.1"
                     /translation="MEKKYFEIHGVPSILWGNPSSKLYIYIHGQCGNKEEAEAFANIA
                     VPHECQVLSVDLPEHGERKREKNSFNPWHVVPELVSIMEYAKCHWNQISLYANSIGAW
                     FSMLSFEKENLRECIFVSPILDMQQLISNMMLWANVSEEQLKHELIIPTSFGHTLSWE
                     YLQYVKQHPITQWNIPTKILYGKHDELTEIGVVEKFVEKFNCNLTIVENGKHWFNTPQ
                     ELNSLYEWLNTLVK"
BASE COUNT          354 a          111 c          134 g          316 t
ORIGIN      
        1 ttaaattagt tttaatacta atataattag tattatatta aattctatat tacaacatta
       61 ttttatagtt tgattaattt aataatcact aatatatcaa actgaaagga gatttttatg
      121 gaaaaaaaat atttcgaaat tcatggagtt ccttcaatcc tttggggaaa tccttcaagt
      181 aaattatata tttacataca tggacaatgt ggcaataaag aggaggctga agcttttgct
      241 aatattgcag ttccacatga gtgtcaagtt ttaagtgttg atttgcctga acatggagaa
      301 cgtaaaagag aaaaaaattc atttaaccca tggcatgttg ttccagaatt agtatctatt
      361 atggaatatg caaagtgcca ctggaatcaa atttcgttat atgcaaatag cattggagca
      421 tggtttagta tgttaagctt tgaaaaagag aacttaagag agtgtatttt tgtatctcca
      481 attctagata tgcaacagct catttcaaat atgatgctct gggcaaatgt atcagaagaa
      541 cagcttaaac atgaactaat tatcccaact tcatttgggc atactctttc atgggaatat
      601 ctacaatatg taaaacaaca tcctatcact caatggaata taccaacaaa aatattatat
      661 ggtaaacatg atgaacttac tgaaatcggt gttgtagaga aatttgtaga aaagtttaat
      721 tgcaacctta ctattgtaga aaatggcaaa cattggttta acacaccaca agaattaaat
      781 tcattatatg aatggttaaa tactttagtt aaataaaaaa taattatatt attaatatga
      841 ttaaattatt tataaatgtt atttaattaa ttttatttta gcattattaa aataactaca
      901 taaagaataa attag
//
LOCUS       DAJMZY010000246          897 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.256, whole genome shotgun sequence.
ACCESSION   DAJMZY010000246 DAJMZY010000000
VERSION     DAJMZY010000246.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 897)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 897)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..897
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.256"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            64..>897
                     /locus_tag="OE968_003825"
     CDS             64..>897
                     /locus_tag="OE968_003825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CorA family divalent cation transporter"
                     /protein_id="HCP7221013.1"
                     /translation="MYILNLNTRETIEDFRDKFYVAENSYLILSAPKNLKLLKETLDI
                     DEITFNDCLKFDEITKLDLFDNYDFLSLNTFELRDGEAVIEEVNMYLSDNFILVVVNE
                     EHFLFEFVKNIILKNSQLEKNPVINLFKINYLILREVIKNGFESLEKVEELILQIEDE
                     MMDNINKNHVSRISDVRGLTRIIVKNTRPLLYIGDRIVKENIRYLKYSNVKKYNLENF
                     QGIDFGIDKLYNFALSTRELADKLLDIYSSRVGEKTNNLITKLTLLTAISAPLTIITG
                     IY"
BASE COUNT          372 a           76 c          138 g          311 t
ORIGIN      
        1 aataattaca gtaaggatta taaaaaattt ttagaatgta aattgaaatt taggagtaga
       61 tgtatgtata tactgaattt aaatacaaga gagactattg aagattttag agataaattt
      121 tatgtagcag aaaattctta tcttatatta agtgctccaa aaaatttaaa attgcttaag
      181 gaaactttgg atatagatga aataactttt aatgattgtc ttaaatttga tgaaataacc
      241 aaacttgatt tatttgataa ttacgatttt ttaagcctaa atacatttga actaagagat
      301 ggagaagctg ttatagaaga ggtaaatatg tatttatcag ataattttat attggttgta
      361 gtgaatgaag aacacttttt atttgaattt gtaaaaaata ttattttgaa gaactctcaa
      421 cttgaaaaaa atccagttat taatctattt aagataaact acttgattct tagagaagtt
      481 ataaaaaatg gttttgagtc tttggaaaaa gttgaagagt taattcttca aatagaagat
      541 gaaatgatgg acaacattaa taagaatcat gtatctagaa taagtgatgt aagaggatta
      601 acaagaatta tagttaagaa tactagacct cttttgtata ttggggatag aatagttaag
      661 gaaaatataa gatatttaaa atattcaaat gtaaaaaaat ataatttaga aaattttcaa
      721 ggtatagatt ttggaattga caaattatac aatttcgcat tgtcaacacg agagttagca
      781 gataaattat tagatattta ttcttccaga gtaggtgaga aaacaaataa cttaattaca
      841 aaattaacct tgttaacagc catatcagca ccacttacaa ttataactgg tatatat
//
LOCUS       DAJMZY010000247          868 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.257, whole genome shotgun sequence.
ACCESSION   DAJMZY010000247 DAJMZY010000000
VERSION     DAJMZY010000247.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 868)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 868)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..868
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.257"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            <1..828
                     /locus_tag="OE968_003826"
     CDS             <1..828
                     /locus_tag="OE968_003826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase"
                     /protein_id="HCP7221014.1"
                     /translation="KNNYNKIRKIFKLYALEISKNFERDCLNSFQNLKQISDRGLSLG
                     EKYIEESFKKGIETIVSFGIITIDIDTFKSVYCEKYLDFKRLFNNLNKTFIIPNKNKK
                     NGHASFLEIESTIKKMSNYLYNDCFKIHYAVVDALIENRITAVHSYIDEESIKKSNAL
                     FNNYKDGFIGKADECKVVKQIITLNPYREDVYEFLVKEDGDFSKEIERLTEFLGYDIR
                     EYKASLMDIYINELMESDENDVENAKEKIEKYARYIGCSDENLYVARVNAIYTFANA"
BASE COUNT          369 a           65 c          145 g          289 t
ORIGIN      
        1 aaaaataatt ataataagat aaggaaaatc tttaaattat atgctttaga aatatctaaa
       61 aactttgaaa gagattgttt aaatagtttt caaaatctaa agcaaatatc tgatagaggt
      121 ttaagtttag gagaaaaata tatagaagag tcttttaaga aaggaattga gactatagta
      181 agttttggaa ttataactat agatatcgat acctttaaaa gtgtttattg tgaaaaatat
      241 ttagatttta agagactttt taataatttg aataaaactt ttattatacc aaataaaaat
      301 aaaaaaaatg gccacgcgag cttcttagaa atagaatcga caataaagaa aatgagcaat
      361 tatttataca atgattgttt taaaattcat tatgctgttg tagatgccct tatagaaaat
      421 cgtataactg cggtacattc ttatattgat gaagaatcta taaaaaaatc taatgcctta
      481 tttaataatt ataaagatgg ttttattggg aaggctgacg aatgcaaagt agtaaaacaa
      541 ataataactt taaatccata tagggaagat gtatacgaat ttttggtaaa agaagatgga
      601 gattttagta aggaaattga gagattgact gaatttttag gctatgatat aagagaatat
      661 aaagcgtcat taatggatat ttatataaat gagttaatgg agagcgatga aaatgatgtt
      721 gaaaatgcaa aagaaaagat tgaaaaatat gctagatata ttggatgtag tgatgagaat
      781 ttatatgtag caagagttaa tgccatatat acttttgcaa atgcataatt ttattaaaca
      841 ttaaatatta gatgttcgat tatataaa
//
LOCUS       DAJMZY010000248          855 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.258, whole genome shotgun sequence.
ACCESSION   DAJMZY010000248 DAJMZY010000000
VERSION     DAJMZY010000248.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 855)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 855)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..855
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.258"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            128..748
                     /locus_tag="OE968_003827"
     CDS             128..748
                     /locus_tag="OE968_003827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HCP7221015.1"
                     /translation="MQYIQELLDLTQNYWVLATIIGLLSAFIESFIPALPLVAIVTAN
                     AAIQGLFIGCLLSWIGSGLGTTSLFLLISRFNDSKLFNKLRNSKTEKAISWMDKQGFK
                     LLFIAYACPFMPGCLVTIASAFGKKDLKDFVPAMLAGKFVMFIVISYVASDIEGFITS
                     PLKIASFILLVFLSWKIGNRVNKNLENHNYDFHHKKHHNDKDDKMI"
BASE COUNT          311 a           89 c          142 g          313 t
ORIGIN      
        1 tataccttaa ctgtaaactt atatagatta tttacttttt aatattagat tcattttttg
       61 agattggtat ataataaaca tatagagtat ataataatag ttaaagttaa aaaaggggaa
      121 aagcaatatg cagtatatac aagaactact tgatttgact caaaattatt gggtgttagc
      181 cacaataatc ggcttattaa gtgcatttat agaaagcttt ataccagcct taccacttgt
      241 tgctatagtt acagcaaatg ctgcaataca aggattattt attggatgtt tgttatcatg
      301 gattggctca ggacttggga caacttcatt attcttatta ataagcagat ttaatgatag
      361 taagcttttt aataagttga gaaatagtaa aactgaaaaa gcaataagtt ggatggataa
      421 acagggattt aagttattat ttatagcgta tgcctgtcca tttatgcccg gttgtttagt
      481 tactatcgca tcagcttttg gtaaaaaaga tttaaaagat tttgtgccag caatgttggc
      541 aggaaaattt gtaatgttta tagttataag ttacgtggca agtgatatag aaggttttat
      601 aacaagtcct ttaaagatag catcatttat attattggtg tttttgtcat ggaagattgg
      661 aaatagagta aataaaaatc ttgaaaatca taattatgat ttccatcata aaaaacatca
      721 caatgataaa gatgataaaa tgatttagct tgtacgaaat aaaacgtatc ttaaaatgat
      781 ttagtactaa attattttaa gatacgtttt attttttgta ttaaggtaca aaatttttag
      841 ttcttttgta aacta
//
LOCUS       DAJMZY010000249          851 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.259, whole genome shotgun sequence.
ACCESSION   DAJMZY010000249 DAJMZY010000000
VERSION     DAJMZY010000249.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 851)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 851)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..851
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.259"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            37..801
                     /locus_tag="OE968_003828"
     CDS             37..801
                     /locus_tag="OE968_003828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HCP7221016.1"
                     /translation="MFAEERIQAILNILKKEGRVTVKELSSKFNVTEDCIRKDLKNIE
                     KISSIRRIYGGAVLARETLENQDTKDRKEINIPTKKIIAEKAFNLIEDRETIFLDIST
                     INILLAKLLAESNKKVTLVTNMLDILNVVTSKPNNLNIISTGGLLNLSLDGFVGTPTI
                     EFISKYKFDKTFMGSCGVDVFNSSLTTFEIEDGLTKKAIINSSKKVFIVMEDKKFKFD
                     GNFKFAHLEDISSIITEKTPTPDIVDILSEFNVNVL"
BASE COUNT          349 a           85 c          135 g          282 t
ORIGIN      
        1 tttactataa tactatattg cgaaaagagg tagaaaatgt ttgcagaaga aagaatccaa
       61 gctatattaa atatcctaaa aaaagaaggt agagttactg tcaaagagct cagttctaaa
      121 tttaatgtta cagaagattg tataagaaaa gatttaaaaa atatagaaaa gatttcttca
      181 ataagaagaa tttatggagg agctgtacta gctagagaaa cactagagaa tcaggataca
      241 aaagacagaa aagaaattaa tattccaaca aagaaaataa tagcagaaaa agcatttaat
      301 ttaattgaag atagagaaac tatattttta gatatctcta caattaacat cttgcttgcg
      361 aagttgttag ctgaaagtaa taaaaaagta acacttgtta caaatatgct ggatatacta
      421 aatgtagtta cttcaaaacc aaataattta aatataattt ccactggagg tttattaaat
      481 ctcagtttag acggttttgt cggtactcca actatagagt ttatatcgaa atataagttt
      541 gataagactt ttatgggaag ttgtggagta gatgtattca actcttcact tacaactttt
      601 gaaattgaag atggtcttac gaagaaggct ataataaatt caagtaaaaa agtatttata
      661 gttatggaag ataaaaagtt taaatttgat ggaaatttca agtttgctca tttagaagat
      721 attagttcta taattacaga aaaaacgcct actcctgata tagtagatat tttatcagaa
      781 tttaatgtaa atgttttata agtttaatta tatgttttat aggatttctt ataaatataa
      841 atttttattt g
//
LOCUS       DAJMZY010000250          809 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.260, whole genome shotgun sequence.
ACCESSION   DAJMZY010000250 DAJMZY010000000
VERSION     DAJMZY010000250.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 809)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 809)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..809
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.260"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            65..442
                     /locus_tag="OE968_003829"
     CDS             65..442
                     /locus_tag="OE968_003829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HCP7221017.1"
                     /translation="MTITKIPPAELKVMKFIWSSDFTVASKDVIEAMEKLYNWKQTTT
                     LTLLSRLVNKQFLSARKIDRHTHYTVLIGEEEYLHFETKTFLDNMHGSSIESFMKSLF
                     KKGVNEEELNSVEKWVKDIKKDE"
BASE COUNT          317 a           62 c          126 g          304 t
ORIGIN      
        1 gactcgaaaa gtctattaat atagtattta attatgtaga agtttgagag gagtgtaaaa
       61 tcatatgact attactaaga taccaccagc agaattaaaa gtcatgaaat ttatttggag
      121 ttcagatttt acagtagcat caaaagatgt cattgaagct atggaaaaac tatataattg
      181 gaagcaaact acaacactaa cacttttatc aagattagta aataagcaat tcttaagtgc
      241 aagaaaaatt gatagacata cacattatac agttcttatt ggagaagaag agtatttaca
      301 ttttgaaaca aaaacttttt tagataatat gcatggaagt tctattgaga gttttatgaa
      361 atccttgttc aaaaaggggg taaatgaaga agaattgaac tctgttgaaa aatgggttaa
      421 agatattaaa aaagatgaat aatttggtgt agttaattat cataaaataa atagttttta
      481 caataattag ttaaatgaat caaatataaa gttttatgta aaatttgtga tttttataaa
      541 tatttttgtc ttgttattta atattaatac aataagtttg atgtaaaatc aaacctgttt
      601 gaatttaatt tatattgggt ttgtcattaa tattatttta gtttgatatt gtatacgaat
      661 ttaaaagtca gaatttttgt atattaatca tgtaaattaa ttgttttaga tataaagggc
      721 ataattttat ttttgttttg attatttcta gggtaagata agtatacaat agattgtatt
      781 aaacatgctt atattgatag atttgagat
//
LOCUS       DAJMZY010000251          808 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.261, whole genome shotgun sequence.
ACCESSION   DAJMZY010000251 DAJMZY010000000
VERSION     DAJMZY010000251.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 808)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 808)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..808
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.261"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            <1..326
                     /locus_tag="OE968_003830"
     CDS             <1..326
                     /locus_tag="OE968_003830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HCP7221018.1"
                     /translation="FSNILDNAIEACNKIDSGNRVICVKGDVMQNFYLIRVENTKMNK
                     IITKNGDILTDKKGSLHGLGIKSVKNSVNKYGGNVVIEYDDKKFVVKIAIPLRNVKKA
                     VNHVI"
BASE COUNT          349 a           29 c          131 g          299 t
ORIGIN      
        1 tattttcaaa tattttagac aatgcaattg aggcatgtaa taaaattgat agtggaaata
       61 gagttatttg tgttaaaggt gatgttatgc aaaattttta tttaataaga gttgaaaata
      121 ctaagatgaa taagattatt actaaaaatg gagatatttt gacagacaaa aaaggttctc
      181 ttcatggact tggaataaaa agtgtaaaaa actctgtaaa taagtatggt ggtaatgttg
      241 taattgaata tgatgataaa aaatttgtag ttaaaattgc tattccactt agaaatgtga
      301 agaaagcagt taatcatgtg atttaaatgt atataaattt gatgtgtaga aatttaatat
      361 ataagaatta atgtataaaa gtgatgcata gaagtttaat atataagaat taatgtataa
      421 aagtgatgta tagaagttta atatataaga attaatgtat aaaagtgatg tatagaagtt
      481 taatatataa gaatttaata tgtataaaag tgatgcataa aagtttaata tataggaatt
      541 taatatgtat aaaagtgatg cataaaagtt taatatatag gaatttaata tgtataaaag
      601 tgatgcatag aaatttaata tataagaatt taatatgtat aaatgtggtg catagaagtt
      661 taatgtaaaa atttggtgta taagaattta atatatatat atttatttta atatataaat
      721 tgaagatata taattaaatc atataatgac atttgtatat tagaattgtt tattgattat
      781 tagaaacttt taaggttaga aagtttat
//
LOCUS       DAJMZY010000252          756 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.263, whole genome shotgun sequence.
ACCESSION   DAJMZY010000252 DAJMZY010000000
VERSION     DAJMZY010000252.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 756)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 756)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..756
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.263"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            <1..372
                     /locus_tag="OE968_003831"
     CDS             <1..372
                     /locus_tag="OE968_003831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCP7221019.1"
                     /translation="DFLQKLSTKLIKENDIICIEDLQVKNMIKNHKLSRLISDVSWSE
                     FIRQLEYKANWYGRQIVKVGKFFASSQICNKCGYKNEEVKDLNIREWICPSCNETHDR
                     DINASINILKEGLRLITIQNK"
BASE COUNT          321 a           82 c          103 g          250 t
ORIGIN      
        1 gattttctac aaaaactatc tactaaatta ataaaagaga atgatattat ttgcatagaa
       61 gatttacaag taaagaatat gattaaaaat cataaactat ctcgcttaat ttcagatgta
      121 tcatggtcag aatttattcg tcaattagaa tacaaggcta attggtatgg tagacaaatt
      181 gtaaaggtag gtaaattctt tgcaagttca caaatatgca ataaatgtgg gtataaaaac
      241 gaggaagtga aggacttaaa tataagagaa tggatttgtc ctagttgtaa tgaaactcac
      301 gatagagata taaatgcaag tataaatata ttaaaagaag gattaagact aataacaatt
      361 caaaataaat aacttatgta agaaccgtag gaactacggg gattgcctgt ggagaattag
      421 taagacatat tttagtatgc aaaattctat gaagcaggaa ccctgtgact ttagtcatgg
      481 gaggttcagt ttagcttaaa acttacttat ctatttcagt ttctattaga attattatta
      541 gactcattaa aataaaagca ctaatataac taataatata tgttaaattc attaactcta
      601 cataaagttt tacaatctaa atgaaataca ataatctgca taaaattcaa tagcttatat
      661 aaaatttaat aatttatata aacattatca atctatataa aatttagtaa tttatataaa
      721 tattatcaac ctatataaaa tttaataact tatata
//
LOCUS       DAJMZY010000253          736 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.264, whole genome shotgun sequence.
ACCESSION   DAJMZY010000253 DAJMZY010000000
VERSION     DAJMZY010000253.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 736)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 736)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..736
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.264"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            <1..624
                     /locus_tag="OE968_003832"
     CDS             <1..624
                     /locus_tag="OE968_003832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HCP7221020.1"
                     /translation="AYYRRMQMRKEQDPEGYKVYGLGEWGETGGAILKNYVIHEFTTE
                     FEYFDNMRLSQDFGFNHANVVLRIGFKDGELYICNEIYVHEMDTSEIIKIANSIGLEK
                     TLFMYCDSAEPDRIKMWKNAGYKAKGVKKGPGSVKAQIDYLKQLRIHVHPSCTNTIKE
                     IQQWKWKQDERTGLYLDEPVEFMDDAMAALRYSIDNKLKNNGISFLK"
BASE COUNT          305 a           83 c          147 g          201 t
ORIGIN      
        1 gcttactaca gaagaatgca aatgagaaaa gagcaagacc cagaagggta caaagtctat
       61 ggtcttggag aatggggaga aactggtgga gcaatactta aaaattatgt tatacatgaa
      121 tttactacag aatttgagta ttttgacaat atgaggttat cacaagactt tggatttaac
      181 catgcaaatg tagtacttag aattggcttt aaggatggag agttatatat atgtaacgaa
      241 atatatgtac atgaaatgga tacctcagaa atcataaaga ttgcaaatag tataggttta
      301 gaaaagactc tatttatgta ctgtgatagt gctgaaccag atagaattaa gatgtggaag
      361 aatgcaggat ataaagctaa aggagttaaa aaagggccag gaagtgttaa agctcaaata
      421 gattatttga aacaattaag aatacatgta catcctagtt gcactaatac cataaaagaa
      481 atacaacaat ggaaatggaa acaagacgaa agaactggat tatatcttga tgaaccagtt
      541 gagtttatgg atgatgcaat ggctgctctt agatattcta tagataataa gcttaaaaat
      601 aatggaataa gcttcttaaa gtaaaggagg tgttaaatat ttatataagt gaaacagatt
      661 taataaaagt tcagttaaaa aaagagagca cctttaacct agtaaaagtc atagaacact
      721 acatcttaaa acatag
//
LOCUS       DAJMZY010000254          736 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.265, whole genome shotgun sequence.
ACCESSION   DAJMZY010000254 DAJMZY010000000
VERSION     DAJMZY010000254.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 736)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 736)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..736
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.265"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            <1..624
                     /locus_tag="OE968_003833"
     CDS             <1..624
                     /locus_tag="OE968_003833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HCP7221021.1"
                     /translation="AYYRRMQMRKEQDPEGYKVYGLGEWGETGGAILKNYVIHEFPTE
                     SEYFDNMRLSQDFGFNHANVVLRIGFKDGELYICNEIYAHEMDTSEIIKIANSIGLEK
                     TLFMYCDSAEPDRIKMWKSAGYKAKGVKKGPGSVKAQIDYLKQLRIHVHPSCTNTIKE
                     IQQWKWKQDERTGLYLDEPVEFMDDAMAALRYSIDNKLKNNGISFLK"
BASE COUNT          304 a           85 c          149 g          198 t
ORIGIN      
        1 gcttactaca gaagaatgca aatgagaaaa gagcaagacc cagaagggta caaagtctat
       61 ggtcttggag aatggggaga aactggtgga gcaatactta aaaattatgt tatacatgaa
      121 tttcctacag aatctgagta ttttgacaat atgaggttat cacaagactt tggatttaac
      181 catgcaaatg tagtacttag aattggcttt aaggatggag agttatatat atgtaacgaa
      241 atatatgcac atgaaatgga tacctcagaa atcataaaga ttgcaaatag tataggttta
      301 gaaaagactc tatttatgta ctgtgatagt gctgaaccag atagaattaa gatgtggaag
      361 agtgcaggat ataaagctaa aggagttaaa aaaggaccag gaagtgttaa agctcaaata
      421 gattatttga aacaattaag aatacatgta catcctagtt gcactaatac cataaaagaa
      481 atacaacaat ggaaatggaa acaagatgaa agaactggat tatatcttga tgaaccagtt
      541 gagtttatgg atgatgcaat ggctgcgctt agatattcta tagataataa gcttaaaaat
      601 aatggaataa gcttcttaaa gtaaaggagg tgttaaatat ttatataagt gaaacagatt
      661 taataaaagt tcagttaaaa aaagagagca ccattaacct agtaaaagtc atagaacact
      721 acatcttaaa gcatag
//
LOCUS       DAJMZY010000255          732 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.266, whole genome shotgun sequence.
ACCESSION   DAJMZY010000255 DAJMZY010000000
VERSION     DAJMZY010000255.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 732)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 732)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..732
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.266"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            119..259
                     /locus_tag="OE968_003834"
     CDS             119..259
                     /locus_tag="OE968_003834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7221022.1"
                     /translation="MEKSNTTVTKKEKIEDIGMKLEHLLSEDITFYELLLEILYKEKE
                     EN"
     gene            complement(256..627)
                     /locus_tag="OE968_003835"
     CDS             complement(256..627)
                     /locus_tag="OE968_003835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCP7221023.1"
                     /translation="MESLGDRIANLRKELDINQKELATKVGITEASLSRYENNLREPK
                     SEIIVRLAKALETSTDYLLGVNDNTKISKEDKLIIENLSVSEKTKKLLEKIYSLEKED
                     REAIEKMIDNAYLKRFLKEEN"
BASE COUNT          263 a           87 c           86 g          296 t
ORIGIN      
        1 tttggataat caaaatatat tttataaaat caaaatacaa ttacataaac tttattaaaa
       61 atttgttggg aatttctgac taacattaag aacgtaagtt tgttggggga tggtatatgt
      121 ggaaaagtca aacactactg ttacaaaaaa agaaaaaatt gaagatatag gaatgaaatt
      181 agaacattta ttgagtgaag atattacttt ttatgaatta ttacttgaga ttttgtataa
      241 agaaaaagaa gagaattaat tctcttcttt aaggaatctt tttaaatagg cattatcaat
      301 cattttttct atagcttctc tatcttcttt ttcaagagaa tatatttttt ctaagagctt
      361 ttttgttttt tcacttactg ataagttctc tatgattaat ttatcttctt tgcttatttt
      421 tgtattatca tttacgccta ataaataatc tgttgatgtt tctaatgctt ttgctaatct
      481 aactattatt tcacttttag gttctcttaa attattttca taacgtgaca agctagcctc
      541 agttataccg actttagtag caagttcttt ttgatttata tctaattctt ttcgtagatt
      601 tgctattcta tctcctaaac tttccatatg tacatcactc cttaccgaaa ttataagtta
      661 ttttgataaa aagtaaaata aaattaccaa aaatataaaa aaaaaaggtt aaaataataa
      721 aatatattga aa
//
LOCUS       DAJMZY010000256          697 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.267, whole genome shotgun sequence.
ACCESSION   DAJMZY010000256 DAJMZY010000000
VERSION     DAJMZY010000256.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 697)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 697)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..697
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.267"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            136..618
                     /locus_tag="OE968_003836"
     CDS             136..618
                     /locus_tag="OE968_003836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HCP7221024.1"
                     /translation="MYNNIKNILKENHITFEEYDHEPILSFEKAKEIREKLQYTGVES
                     KSLFIKDRSGNYYIFVTTEGKKLDPKTIKNVLGGKVSICSKEELTQKTQCLPGCVSPF
                     GYEKNISLVIDQDIFNHDKIIFSPGIPEKTFIITASGFKKVINNINNTTYKYIYINEF
                     "
BASE COUNT          321 a           66 c           81 g          229 t
ORIGIN      
        1 ttatcttata acctatttta tataatttat tcctaaaaca tgtgaatgtt ttttatgata
       61 gtttgaagaa attataaaat cactttataa ttgaatatta tatataaatt aatttaaata
      121 tagaaaggaa aatatatgta caacaatatc aaaaatattt taaaagaaaa tcatataacg
      181 tttgaagaat atgaccatga acctatttta tcatttgaaa aagctaaaga aataagagaa
      241 aaattacaat atactggagt agaaagtaaa agtttattta taaaagatag gtctggaaat
      301 tactatatat ttgtaaccac agaaggaaaa aaattagatc caaaaactat aaaaaatgtt
      361 ttaggtggaa aagtatctat atgttcaaaa gaagaattaa cacaaaaaac acaatgtttg
      421 cctggatgtg tatctccttt tggatatgag aaaaatatct ctcttgtaat agatcaagat
      481 atatttaacc atgataaaat aatcttttca ccagggatac cagaaaagac atttattatt
      541 acagctagtg gatttaaaaa agtaataaat aatataaaca atacaactta taaatatata
      601 tatattaatg aattttaatc ataattgtaa attagagaaa ataacattag aaatcatgct
      661 taactatagt gtaaataaat tatattcaac acaaaag
//
LOCUS       DAJMZY010000257          644 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.271, whole genome shotgun sequence.
ACCESSION   DAJMZY010000257 DAJMZY010000000
VERSION     DAJMZY010000257.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 644)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 644)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..644
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.271"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
BASE COUNT          204 a          142 c          120 g          178 t
ORIGIN      
        1 atgatagcat tgaaggatga gactaatcca attgaggagt ggcagcatat agaacagcta
       61 aagggtagtg ctgaaggaag catacgatac cccgcatgga atgggataat atcacaggag
      121 gtactagact acctttcatc ctacataaat agacgcatat aagtacgcat ttaagcataa
      181 acacgcacta tgccgttctt ctcatgtata tatatataca ggcaacacgc agatataggt
      241 gcgacgtgaa cagtgagctg tatgtgcgca gctcgcgttg cattttcgga agcgctcgtt
      301 ttcggaaacg ctttgaagtt cctattccga agttcctatt ctctagaaag tataggaact
      361 tcagagcgct ttgaaaacca aaagcgcttt gaagacgcac tttgaaaaat ccaaaaacgc
      421 accgcaccgt aactactaca ccgcgaatac tgtgccctga aacattgctc aaaagtatct
      481 ctttgctata tatctctgtg ctatatccct atataaccta cccatccacc tttcgctcct
      541 tgaacttgca tctaaactcg acctctacat tttttatgtt tatctctagt attactcttt
      601 agacaaaaaa attgtagtaa gaactattca tagagtgaat cgaa
//
LOCUS       DAJMZY010000258          590 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.273, whole genome shotgun sequence.
ACCESSION   DAJMZY010000258 DAJMZY010000000
VERSION     DAJMZY010000258.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 590)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 590)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..590
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.273"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            163..447
                     /locus_tag="OE968_003837"
     CDS             163..447
                     /locus_tag="OE968_003837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7221025.1"
                     /translation="MLVYNKSFYPNDIFPRLDFSKIKKQLKLIDNDLSDFGSICIIEK
                     EHYTISVNSIGEINVYYDLEYENKVYRIVYEIEKLFKSQVGRFSISTYRN"
BASE COUNT          258 a           41 c           88 g          203 t
ORIGIN      
        1 atattttact aatatacatt taaaaattac aatttaaagc attaaaaaat aaatttgtat
       61 tttgttttat ataaagtaat ttgaaaaata tggaaaaatt gattagtaca ttattaatta
      121 gggtataaaa tggtgtaaat agaatgataa ggggtggatg aaatgcttgt atataataaa
      181 agtttttatc ctaatgacat atttccaaga ttagattttt caaaaataaa aaaacagtta
      241 aaattgatag ataatgacct gtcagatttt ggaagcatat gtataataga aaaagaacat
      301 tatacgataa gtgtaaacag tataggtgaa ataaatgtgt actatgattt agagtacgaa
      361 aataaggtgt atagaatagt ttatgagatt gaaaagttat ttaaatctca agttggaagg
      421 tttagcatat ctacatacag aaattgataa ttaaaaaagt agaaattaaa aaacttaata
      481 ctaaagatat agataaatat atgaggtaac agctagagag agttgttacc ctttttaaat
      541 actaagtata tattattctt attaattttt tgtaaattca ctaaaagacc
//
LOCUS       DAJMZY010000259          577 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.275, whole genome shotgun sequence.
ACCESSION   DAJMZY010000259 DAJMZY010000000
VERSION     DAJMZY010000259.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 577)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 577)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..577
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.275"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            <1..>577
                     /locus_tag="OE968_003838"
     rRNA            <1..>577
                     /locus_tag="OE968_003838"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          154 a          121 c          190 g          112 t
ORIGIN      
        1 caggatggac ccgcgtctga ttagctagtt ggtaaggtaa cggcttacca aggcgacgat
       61 cagtagccga cctgagaggg tgatcggcca cattggaact gagacacggt ccaaactcct
      121 acgggaggca gcagtgggga atattgcaca atgggcgaaa gcctgatgca gcaacgccgc
      181 gtgagtgatg aaggccttcg ggtcgtaaaa ctctgtcctc aaggaagata atgacggtac
      241 ttgaggagga agccccggct aactacgtgc cagcagccgc ggtaatacgt agggggctag
      301 cgttatccgg atttactggg cgtaaagggt gcgtaggcgg tctttcaagt caggagtgaa
      361 aggctacggc tcaaccgtag taagctcttg aaactgggag acttgagtgc aggagaggag
      421 agtggaattc ctagtgtagc ggtgaaatgc gtagatatta ggaggaacac cagttgcgaa
      481 ggcggctctc tggactgtaa ctgacgctga ggcacgaaag cgtggggagc aaacaggatt
      541 agataccctg gtagtccacg ctgtaaacga tgagtac
//
LOCUS       DAJMZY010000260          544 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.276, whole genome shotgun sequence.
ACCESSION   DAJMZY010000260 DAJMZY010000000
VERSION     DAJMZY010000260.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 544)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 544)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..544
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.276"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
BASE COUNT          237 a           24 c           60 g          223 t
ORIGIN      
        1 aaagtattta catgtttttt ctatatattt tataagtttt aggtatggaa aattactaaa
       61 taaaaattag attaatgatt atgatagtat agataaagtt tattcttttt attaatagaa
      121 attgttgtat aaaaataata aaagtgagga gagtgatatt taaataaaaa aattttaata
      181 agtattggta atatagtttt tagggatgat tattttatgt aaaaagttgt tatttgtaaa
      241 gataaatata gaaaatatta taagtattga tttagtgata atctaaaagg tgagaattgt
      301 aataaaaaga gaacatatcc ttcaaatgga tgtaaactta taaataacat tattacaaga
      361 gatttattat acatatactg caactattaa ttagaattta tactgtattt gtatttaaat
      421 aaaaacacaa ataatattat tgtaaaaatt tattatattt caaatttaaa gatatttttt
      481 aatacaaaat ttttgtataa taataataat tattatttaa tctaaatata tctatatttt
      541 atac
//
LOCUS       DAJMZY010000261          533 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.277, whole genome shotgun sequence.
ACCESSION   DAJMZY010000261 DAJMZY010000000
VERSION     DAJMZY010000261.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 533)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 533)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..533
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.277"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            <1..>533
                     /locus_tag="OE968_003839"
     CDS             <1..>533
                     /locus_tag="OE968_003839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase large subunit"
                     /protein_id="HCP7221026.1"
                     /translation="RAMKGSAGSGKSVNVAQDYILKLGDKKYQGANLLVVRKSEATHK
                     YSTYAELTGAINRIYGKQADKYWKTTLNPLEIKSKVTGNSIIFRGVNDAKQREKLKSI
                     NFSKGKLTWVWCEEATELMESDIDILDDRLRGILTNPNLYYQMTFTFNPVSATHWIKR
                     KYFDYKNDDIFTHHSTYL"
BASE COUNT          214 a           69 c           96 g          154 t
ORIGIN      
        1 agagcaatga aaggttcagc agggagtgga aaatctgtta atgtagcaca agactatata
       61 ctaaagttag gagataagaa gtatcaagga gctaatctat tagtagttag aaagtcagaa
      121 gctacacata agtattcaac gtatgcagag cttacaggag ctataaatcg tatttatggt
      181 aaacaagctg ataagtattg gaaaactact ttaaatcctt tagaaattaa gagtaaagtt
      241 actggtaact ctataatttt cagaggagtt aatgatgcaa aacaaagaga aaaattaaaa
      301 tcaattaact tctcgaaagg aaaattaaca tgggtttggt gtgaagaagc tacagaactt
      361 atggaaagtg acatagacat actagatgac cgtttaagag gtattttaac taatcctaac
      421 ctatactatc aaatgacatt tacatttaat ccagtctcag ctactcattg gataaaaaga
      481 aagtattttg actataaaaa tgatgatata tttactcatc atagtactta tct
//
LOCUS       DAJMZY010000262          440 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.280, whole genome shotgun sequence.
ACCESSION   DAJMZY010000262 DAJMZY010000000
VERSION     DAJMZY010000262.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 440)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.280"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            complement(<1..>440)
                     /locus_tag="OE968_003840"
     CDS             complement(<1..>440)
                     /locus_tag="OE968_003840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HCP7221027.1"
                     /translation="EEYYYGNTDVNNKRRYYLLDGAKVDDFTKVNNKAINNYHKLLVD
                     QKVGYSVGNPIVFNADDDNLTKLLNDLLGEEFDDTITELYLNASNKGVEWLHPYINRK
                     GEFKYVIIPAEEAIPIWDSKRQRELVAFIRFYYIEDIDGNKIKRV"
BASE COUNT          135 a           84 c           45 g          176 t
ORIGIN      
        1 actcttttta ttttatttcc atctatatct tcaatataat aaaacctaat aaatgcaact
       61 aattccctct gtcttttact atcccaaata ggaattgctt cttcagctgg aattattaca
      121 tatttaaact caccttttct attaatatat ggatgtaacc attcaacccc tttattacta
      181 gcattgagat atagttctgt tattgtatcg tcaaactctt ctcctagtaa gtcatttaaa
      241 agcttagtga gattatcatc atctgcatta aatactatgg gatttccgac actatagcct
      301 accttttggt caactaaaag cttatggtag ttgttaattg ctttattatt aactttagta
      361 aaatcatcaa ccttagctcc atctaagaga taatatcttc tcttattgtt tacatcagta
      421 ttaccataat agtattcttc
//
LOCUS       DAJMZY010000263          436 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.281, whole genome shotgun sequence.
ACCESSION   DAJMZY010000263 DAJMZY010000000
VERSION     DAJMZY010000263.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 436)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 436)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..436
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.281"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
BASE COUNT          177 a           33 c           60 g          166 t
ORIGIN      
        1 gagaaatact ataaactata aacaagaaat atcttttcta agagcatatt gtacaatatg
       61 ctcttaattt agttatatag atttaatata aataatgtat tttttgtaga tgatttatgt
      121 aagatttatg accaatttgt gtatgatttg tgttctttaa tcatgacaat attatattgt
      181 aaaaaataaa tttaataaaa aatgacttgg aatttatatt ctaggtcttt tttatataaa
      241 aatttaataa gtttcaaatg ttggtaactt tgacagtaga aaacgtctat tgagataacg
      301 aggattctaa ttgaggggga gagatattag cacttaaagt agtatatgca acagatataa
      361 tctttacaaa agtaatttga attaaaatgt aaatataaag aataattaaa aaaatatcgc
      421 aattatttgt ttttca
//
LOCUS       DAJMZY010000264          421 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.283, whole genome shotgun sequence.
ACCESSION   DAJMZY010000264 DAJMZY010000000
VERSION     DAJMZY010000264.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 421)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.283"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            188..304
                     /gene="rrf"
                     /locus_tag="OE968_003841"
     rRNA            188..304
                     /gene="rrf"
                     /locus_tag="OE968_003841"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            310..398
                     /locus_tag="OE968_003842"
     tRNA            310..398
                     /locus_tag="OE968_003842"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:344..346,aa:Leu,seq:taa)
BASE COUNT          140 a           71 c           89 g          121 t
ORIGIN      
        1 attcattaag atatatgtgc agtttttaga gtgctaactc tatattttta aacttgtcaa
       61 aacttatgga tttttaatag ttttataagg caaaaaatcg aataaaaaaa gtattgacac
      121 aataagacaa agatgttatt ataatacttg tcttagaaaa aaagttaaat gaaaatttag
      181 acaataatct ggttataata gcagagagga tacacctgtt cccattccga acacagaagt
      241 taagctctct agcgctgatg gtacttggtg ggaaactgcc tgggagagta ggacatagcc
      301 aggtgatgtg ccgaagtggc ggaactggca gacgcacagg acttaaaatc ctgcgggact
      361 tacctctcgt accggttcga ttccggtctt cggcaccaca aattattgtg ggccattagc
      421 t
//
LOCUS       DAJMZY010000265          410 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.284, whole genome shotgun sequence.
ACCESSION   DAJMZY010000265 DAJMZY010000000
VERSION     DAJMZY010000265.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 410)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 410)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..410
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.284"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            complement(<1..>410)
                     /locus_tag="OE968_003843"
     CDS             complement(<1..>410)
                     /locus_tag="OE968_003843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HCP7221028.1"
                     /translation="RVILNDYINTFFYNYNFEYNIKEFENGGDLLKKYPNNVDIIFMD
                     IDLNDENGFNVSKEIKKFDESVRIIFVSSSNKYIKKGYEIGVYRYLEKPLKYSLFKEA
                     ISSYLKECYKNEAILSIKCKCKIYFIKVDDILYL"
BASE COUNT          143 a           58 c           33 g          176 t
ORIGIN      
        1 ctaaatataa aatatcatct acctttatga aatatatctt gcatttacat tttatagata
       61 aaatagcttc atttttgtag cattctttta aatatgatga tattgcttct ttaaatagag
      121 agtattttaa gggcttctct aaatatctat aaactcctat ctcataacct ttctttatgt
      181 atttatttga tgaggataca aatataattc ttacactttc atcaaatttt ttgatttctt
      241 ttgaaacatt aaatccattt tcatcattta agtctatatc cataaatatg atatcaacat
      301 tattaggata cttttttaat aaatcgcctc cattttcaaa ctctttgata ttgtattcaa
      361 aattgtaatt ataaaaaaag gtatttatat aatcatttag aattaccctc
//
LOCUS       DAJMZY010000266          405 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.285, whole genome shotgun sequence.
ACCESSION   DAJMZY010000266 DAJMZY010000000
VERSION     DAJMZY010000266.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 405)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 405)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..405
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.285"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            <1..215
                     /locus_tag="OE968_003844"
     CDS             <1..215
                     /locus_tag="OE968_003844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HCP7221029.1"
                     /translation="IGSHPSFQLFHDLVTMFNISVDEYFYPAEKVAKSTARRQIETSL
                     DLLSDNELKIIQGTIDGILNSRENKK"
BASE COUNT          125 a           73 c           68 g          139 t
ORIGIN      
        1 atatcggttc acacccaagt tttcaattat tccatgattt agttaccatg ttcaatatat
       61 cggttgatga atatttctat ccagcagaga aagttgcaaa aagcacagct cgccgtcaga
      121 tagaaacatc acttgattta ttgagtgata acgaattaaa aattattcaa ggtacgattg
      181 acggtatctt gaacagcagg gagaataaga agtaatcagc ttcttgtttt ccccgttttc
      241 tttttagcca tatttcttca agacttattt gttgatctgc tttgcaggaa acaaataaga
      301 gccgacaatc tataagttac aataacctac aaattatcgg ctctgcgtct tagcgtctgg
      361 ctctttgata atagttactt ttccatgctt tatattgatt aaagt
//
LOCUS       DAJMZY010000267          381 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.287, whole genome shotgun sequence.
ACCESSION   DAJMZY010000267 DAJMZY010000000
VERSION     DAJMZY010000267.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 381)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 381)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..381
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.287"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            87..>381
                     /locus_tag="OE968_003845"
     CDS             87..>381
                     /locus_tag="OE968_003845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComEC/Rec2 family competence protein"
                     /protein_id="HCP7221030.1"
                     /translation="MGVIIIQIRRPLLIILMFVVAISFIITNNTKNDEELNDKIITIQ
                     GVVKGKIEKKRYNQYKVGVFLINDYTKNKNLKIGQKVNITGKFKSLDKMKYDDF"
BASE COUNT          164 a           30 c           55 g          132 t
ORIGIN      
        1 cttttgacgt atttttttgt ttagataaca atttatcttg tttaaaaatt ttctatttga
       61 aaataatcta aataatatac ttttatatgg gagtgattat aattcaaata agaagaccat
      121 tattaattat attaatgttt gtggtagcta tatcatttat cattacaaat aacacaaaaa
      181 acgacgaaga acttaatgat aagataataa ctatacaagg agttgtcaaa ggaaaaattg
      241 aaaagaaaag atacaatcag tacaaggtag gggtttttct aataaatgat tatacaaaaa
      301 ataaaaattt gaagattggt cagaaagtta atattacagg taaattcaaa agtttagata
      361 aaatgaagta tgatgatttt g
//
LOCUS       DAJMZY010000268          381 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.288, whole genome shotgun sequence.
ACCESSION   DAJMZY010000268 DAJMZY010000000
VERSION     DAJMZY010000268.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 381)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 381)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..381
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.288"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            complement(<1..>381)
                     /locus_tag="OE968_003846"
     rRNA            complement(<1..>381)
                     /locus_tag="OE968_003846"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT           89 a          107 c           87 g           98 t
ORIGIN      
        1 tgtactaccc attgtagcac gtgtgtagcc ctaagcataa ggggcatgat gatttgacgt
       61 catccccacc ttcctccagg ttatccctgg cagtctctct agagtgccca acttaatgat
      121 ggcaactaaa gacaagggtt gcgctcgttg cgggacttaa cccaacatct cacgacacga
      181 gctgacgaca accatgcacc acctgtcacc aatgtccccg aagggaactc tccgattaag
      241 gagatgtcat tgggatgtca agcttaggta aggttcttcg cgttgcttcg aattaaacca
      301 catgctccgc tacttgtgcg ggtccccgtc aattcctttg agtttcactc ttgcgagcgt
      361 acttcccagg cggagtactt a
//
LOCUS       DAJMZY010000269          364 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.291, whole genome shotgun sequence.
ACCESSION   DAJMZY010000269 DAJMZY010000000
VERSION     DAJMZY010000269.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 364)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 364)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..364
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.291"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            168..284
                     /gene="rrf"
                     /locus_tag="OE968_003847"
     rRNA            168..284
                     /gene="rrf"
                     /locus_tag="OE968_003847"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            291..362
                     /locus_tag="OE968_003848"
     tRNA            291..362
                     /locus_tag="OE968_003848"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:323..325,aa:Asn,seq:gtt)
BASE COUNT          117 a           61 c           78 g          108 t
ORIGIN      
        1 attcattaag atatatgtgc agtttttaga gtgttaactc tatgtaaagt actaacttca
       61 attgatgaag tatatatcgt aaaaacaatt actatttagt acttcaaaac tattgacatt
      121 taaaaataaa gatgttaata taatacttgt cttataaata ggcaatatgt ggttataata
      181 gcaaagagga tacacctgtt cccattccga acacagaagt taagctcttt agcgctgatg
      241 gtacttggtg ggaaactgcc tgggagagta ggacgtagcc acgtgaatat tccaaggtag
      301 ctcaatggtg gagcaaccgg ctgttaaccg gtaggctgtg ggttcgagcc ccacccttgg
      361 agcc
//
LOCUS       DAJMZY010000270          363 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.293, whole genome shotgun sequence.
ACCESSION   DAJMZY010000270 DAJMZY010000000
VERSION     DAJMZY010000270.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 363)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 363)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..363
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.293"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            <1..208
                     /locus_tag="OE968_003849"
     CDS             <1..208
                     /locus_tag="OE968_003849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HCP7221031.1"
                     /translation="IKKFFNTSGMKYRELGLKDIVKTESDDKLLEILVSDGMLIKRPL
                     LLDGKNVLLGFKEDVWKSTLLKED"
BASE COUNT          151 a           27 c           53 g          132 t
ORIGIN      
        1 tataaagaaa ttttttaata caagtggtat gaaatataga gaattgggtc ttaaagatat
       61 tgtaaaaact gaatctgatg ataaactttt agaaatattg gtaagtgatg gtatgcttat
      121 taaaagacca ttacttttgg atggtaaaaa tgtattattg ggttttaaag aagatgtatg
      181 gaaaagtact ttgctaaaag aagattagga agagataggt gtgttgatta aaattattaa
      241 ttaatacacc tataaattta tgtattaaat ctaatcttta taaatattaa ttagcaaatt
      301 caaatcaaaa aaattcatat caacaaacat attacttctt attacaaatt atatcatatg
      361 ttt
//
LOCUS       DAJMZY010000271          357 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.denovo.295, whole genome shotgun sequence.
ACCESSION   DAJMZY010000271 DAJMZY010000000
VERSION     DAJMZY010000271.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 357)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 357)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..357
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.denovo.295"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            complement(<1..>357)
                     /locus_tag="OE968_003850"
     CDS             complement(<1..>357)
                     /locus_tag="OE968_003850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HCP7221032.1"
                     /translation="IVNSKYNLDINVTTQNIIETETYQSTYIFYLGELDSKADFDFRL
                     QLCSDLLPHIIKDNAENKFLNLFDLIRYKTLDLINEDNILNKLIDFNKIKSIDEELLY
                     TGIKFINNDLNISKTST"
BASE COUNT          137 a           38 c           34 g          148 t
ORIGIN      
        1 agtagatgtc ttagaaatat ttaaatcatt atttataaat tttattcctg tatatagaag
       61 ttcttcgtca atagatttaa tcttattaaa atctattaat ttattgagta tattatcctc
      121 attaattaaa tctaaagttt tatatctaat aaggtcaaac aaatttaaaa acttattttc
      181 agcgttgtct tttataatat gaggtagtaa atcagaacat aactgtaatc taaaatcaaa
      241 atcagcttta ctatctaatt caccaagata aaaaatataa gtactttgat aagtttcagt
      301 ttcaattata ttttgtgtag ttacattaat atctaagtta tatttagaat ttactat
//
LOCUS       DAJMZY010000272        16235 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.guided.093, whole genome shotgun sequence.
ACCESSION   DAJMZY010000272 DAJMZY010000000
VERSION     DAJMZY010000272.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16235)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16235)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16235
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.guided.093"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            complement(<1..632)
                     /locus_tag="OE968_003851"
     CDS             complement(<1..632)
                     /locus_tag="OE968_003851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HCP7221033.1"
                     /translation="MKLGLCLEGGGAKGAYQAGVVKALYDGGINKFYSISGTSIGAIN
                     GYYLYTGNVDNLEKMWTNIKDIQNGNVKIVNNTVDNSPAIDNLRELDDSNIEEMNFYV
                     NYVEVDNKVVSEKIVDVSKMPRNEAIISISYSGLLPSNPNATLGFKEQFVKDVQEGIY
                     DGFKLDGGLIRSALIEPLIGDNVDKIILISTKYNYELPEDIKKVYDEDKI"
     gene            complement(663..1961)
                     /locus_tag="OE968_003852"
     CDS             complement(663..1961)
                     /locus_tag="OE968_003852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M18 family aminopeptidase"
                     /protein_id="HCP7221034.1"
                     /translation="MDSINFAKNLIDFIYDSPSSFHAVKSTKEILDKNGFEELVLNQR
                     WNLRVGGKYYVTKNLSAIVAFVVNSEDIERDGFRIIGSHSDSPTFSIKPNAEIEAEKS
                     YLKLNTECYGGAILSTWLDRPLGIAGRVVLKGDSILKPNERLIDFKKPICIIPNLAIH
                     LNRSINDGHSYNKQKDMLPLVGMLNDTLEKDNFLIKQIASNLDVNMDDIIDFDLFLYE
                     FEKGSLIGANDEFISIGRQDNLAMVHASLNALVNTKGQHGVNVMAVFDNEEVGSSTKQ
                     GADSNMLLNILERICISMGKDREGFFESIYSSFMISSDLAHAIHPNIPEKHDPTNKPI
                     MGKGPVIKINASQAYTSDGYSIAIYKNICREANVEYQEFVNRSDERGGSTIGPISSTH
                     IDIPSVDVGSPILAMHSIRELGNVEDHYSIYKTFSKFFEI"
     gene            complement(1978..4242)
                     /locus_tag="OE968_003853"
     CDS             complement(1978..4242)
                     /locus_tag="OE968_003853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3553 domain-containing protein"
                     /protein_id="HCP7221035.1"
                     /translation="MNLDTLNPAQREAVEKTEGPVLILAGAGSGKTKVLTTRIAYLIE
                     DKGVQAPNILAITFTNKAANEMRERVEQNIGPETKDMWISTFHSCCVRILRKDINKIG
                     YNRSFVIYDSADQVTLVKDCLKELNLSDKVFEPKAVISAISGAKDKLYTPKQFKDINM
                     ADNRMVKIADIYALYQDRLKRNSALDFDDLILKTVELFKANDEVLAYYRSRFRYIMVD
                     EYQDTSKAQYELIKLLAREHQNICVVGDDDQSIYGWRGADIRNILEFEKDYDNVHVVK
                     LEQNYRSTQVILDAANKVISNNIERKRKKLWSEKKEGELIKIQLTGSEIEEADFIADS
                     IAQIARKENRPYKDFAVLYRANAQARPVEDALNRSQIPYNIYGGTKFYERKEIKDLLA
                     YLRVIQNPQDDISIKRIINVPRRGIGLRTIEKIEDRANLKQESIYSVLIDIETNSDIS
                     TKARASISGFVDIIGTLRTIKEVYPVSKLIEKVLDTTGYMDELVEIRNKNEKDLTGKG
                     EEAQDRIDNLREFISIALEFESSNDDTYENKDLETFLTSIALTSESNDEEDNDRVSLM
                     TIHTSKGLEFPVVFLTGMEEGLFPISRAIKSMSDSQIEEERRLCYVGITRAKEELYMS
                     LTEKRTLYGKTNVAIASRFMEELPEECIERLYKVKKELSYSKASYNMLDKYTKKYMST
                     ISKSKVADKVNATIKDSNKETNPDDIKLGSKVHHPKFGVGTVVSIIGTDVTIAFDQQG
                     IKKINKEYTTLNIL"
     gene            complement(4497..5315)
                     /locus_tag="OE968_003854"
     CDS             complement(4497..5315)
                     /locus_tag="OE968_003854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HCP7221036.1"
                     /translation="MFKINNLTYQYEKNTNALLNINMDFSKGNVIGIIGSNGSGKSTL
                     FMNLMGILKPTSGEILFKEEKLKYDKRSLYNLRKNVGIVFQDPEKQIFYSKVYDDIAF
                     AMRNIGMDEKTIKERINKALVAVNGIDFIDRPVHFLSYGQKKRVAIASVIAMENEIVL
                     LDEPTAGLDPVSTRSIVDIIKGLNKNNIKIVISSHDMNLMYEICDYIYVLDKGILIDE
                     GKAENVFINENNIIQAGLESPWLVKVHRNMNLPLFKKEEDLYKYWKERELNTNK"
     gene            complement(5308..6006)
                     /gene="cbiQ"
                     /locus_tag="OE968_003855"
     CDS             complement(5308..6006)
                     /gene="cbiQ"
                     /locus_tag="OE968_003855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ECF transporter T component CbiQ"
                     /protein_id="HCP7221037.1"
                     /translation="MLIIDKYAYTNRLSKVNPNKKVAIGVIFLIASMVIQNIFILSGI
                     MILMSILVVCVAGIDLKNYLKLLRIPMYFLFLSIGITLVNISFNKADLLYSFEFFSFN
                     VGISKASIDMSIHVLFRAMSCLTCVYFCILTTPFNQLIFFFKKLHLPDTFVELSMLIY
                     RFIFIFLEEFSEIYKSQELRFGYINLKTSYKSLGILGSMLYKRLMTRYDDMCISLDIK
                     LYDGKFHIVGDNDV"
     gene            complement(6009..6287)
                     /locus_tag="OE968_003856"
     CDS             complement(6009..6287)
                     /locus_tag="OE968_003856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     substrate-binding protein"
                     /protein_id="HCP7221038.1"
                     /translation="MSAKTKTNILLLLLVVALIIFPLLVNSGAEYGGADGQAESEITK
                     INPNYKPWFSSPYEPPSGEIESLLFSAQAALGAGVIGYILGLQKGKRS"
     gene            complement(6277..7029)
                     /locus_tag="OE968_003857"
     CDS             complement(6277..7029)
                     /locus_tag="OE968_003857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006440549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter permease"
                     /protein_id="HCP7221039.1"
                     /translation="MKQNIKLGVIAALMLIILTPVTSNAMHIMEGYLPVKWSIAWGVI
                     FIPFFLFGLKSIGKIVKQDPKKKVLLALCGAFVFVLSALKIPSVTGSCSHPTGVGLGA
                     IMFGPSVMFVLGTIVLIFQALLLAHGGITTLGANAFSMAIIGPIVSFLIFKALKKKDG
                     NNAIPVFLAAAIGDLATYTITSIQLALAFPDPSGGVMASAIKFLGIFFMTQIPIAIAE
                     GILTVIVYNLITENGEKSILENNDKGVKANEC"
     regulatory      complement(7211..7403)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            complement(7535..9307)
                     /locus_tag="OE968_003858"
     CDS             complement(7535..9307)
                     /locus_tag="OE968_003858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitric oxide reductase activation-like protein"
                     /protein_id="HCP7221040.1"
                     /translation="MKWIYDDYEFENRANNLSWTIAGDYNESIDISEKDYSSKEIGLY
                     FAIIAGARRKYVDWDIVKKYLTNRIRKGYNKDIILGLIQVILNTIVEEKVIKDRPGIE
                     DIRRNAYKDIVSRFTKIHNDNIMDKIKYTFVLYSMDKHPALDSMTRRIVNDIRNIDTN
                     QDIMEILKALDVIYLTYFEYILNGEENSLIDENNVESVEVNFDTFADFMYEELYSDEE
                     ENIIESDIDSISSSMLVEGVGDFDDSKCSNSADRVIYVDEDTANKIYSKIEHYYGKTY
                     LSKGEIKKIETQNCRNVHEGCRIHFTDGVLRSECNNVFQLKYVTRQKENNLGKFREHA
                     RMYRQQIKRLKESLSRILIEENAKSRVYSDCGTILANRAWRVGRSNNNKIFYKDIENE
                     KGKYVIDILLDASGSQSRNQGNVAIQAYIIANALTEVGIPNRVMGFSSFLDYTILKRF
                     KDYDDSIKNSENIFEYFCAGNNRDGLAIKSICSGLINRDEENKILIVLSDGRPNDVKI
                     GKSSERTLRGEKAYRGIVGLRDTANEVRKARKQNILVLGVFTGKESELEAERLIYGND
                     FIYSRDITRFSDVVSMYLKKIIRN"
     gene            complement(9321..10250)
                     /locus_tag="OE968_003859"
     CDS             complement(9321..10250)
                     /locus_tag="OE968_003859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HCP7221041.1"
                     /translation="MDIIDNLRVQGVDEKLIEDVLYFRNYYGLEKDLEYRVTKSKTYF
                     YGKDILSMCIAAILEEENILLSGPKATGKNLLADNLGEIFNRPQWNTSFHINTDSSTL
                     IGTDTFIDNEVKLRRGSVYECAINGGFGVFDEINMAKNDAIVVVHSALDYRRIIDVPG
                     YERVNLHPATRFIGTMNYEYAGTKELNEALVSRFMVIDIPPIEEDKLMMILKNEFSDA
                     DEEKLIHFAGIFLDLQLKSQNGEISSKAIDLRGLMASLKTIRRGLKPTLAINMGLTGK
                     TFDVYEKEMVGDVIKTRIPNKWESIDVFPISHI"
     gene            10479..10667
                     /locus_tag="OE968_003860"
     CDS             10479..10667
                     /locus_tag="OE968_003860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCP7221042.1"
                     /translation="MEYMSCPEVAKKWGISERRVQKLCEESRIPGVSKLGYMWLIPKN
                     AEKPVDGRTKRRKEVQYE"
     gene            10660..11361
                     /locus_tag="OE968_003861"
     CDS             10660..11361
                     /locus_tag="OE968_003861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCP7221043.1"
                     /translation="MNSVLIIDDDKELCALMKKCVEQENLSAITAHGGAEGLHLVDKN
                     RHTLSLVILDIMMPDIDGFQVLKKIRETSNIPVIMLTAKNDEDDKVSGLRLGADDYLT
                     KPFSINELMARVNSLIRRYTMLNPAFITDTDFIIINGMIIDKTNRIVSVNNIPVQLTS
                     KEFDLLAFLASNKGRVFTKKQIYTQVWEEEYAFDDSNIMSFISKLRKKIEPDPNHPFY
                     ILTVRGVGYRFNKEA"
     gene            11363..12286
                     /locus_tag="OE968_003862"
     CDS             11363..12286
                     /locus_tag="OE968_003862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HCP7221044.1"
                     /translation="MNTSVYLLLILALSLIIIAYLVSVLLRVRIQLTLIKDALEDIKN
                     GNLNRRILTDENDITKQICYDINEIAINSQFQLIQQKQSEQAYKQLMTSLSHDVKTPL
                     ASLVGYLEAVESKIVVGEEKDEYIHVASNKAHYLKNFVENLFEWVKLDSKEQVFHFDI
                     FDLNELSRNIISDWIPVLESSHFEYEFDIPEIEYFLRIDANAYTRIINNLLQNIITHS
                     SGNKMTLRIFENKEQAQIIITDNGKGISSDNLPHIFERLYQCDHSRASKGNGLGLAIA
                     KELINAHKGNITANSTPGMGTEFTILLPKAL"
     gene            12443..13366
                     /locus_tag="OE968_003863"
     CDS             12443..13366
                     /locus_tag="OE968_003863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019639192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCP7221045.1"
                     /translation="MNDFVIETKQLTKIYGNQTVVDKVNLHVKKGRIYGLLGRNGAGK
                     TTIMKMILGLTSITYGEVDVFGENIKGREKQVYPRIGAIIETPGFYPNLTGTENLEIF
                     AKLRGTAAPNSVKRALEIVGLPYKNKKLFSKYSLGMKQRLGIANAILHDPELLVLDEP
                     TNGLDPIGIAEMRKFIRDLSVEHGKTILISSHILSEISLLADDIGIIDHGVLLEESSM
                     SELEKKNSKYILLQVSDIPKTSLILERQFNTKDYSVQDDYTLHLYNTNLDMGEINKAL
                     VMQNVTVISSQLCNDTLEDYFKKITGGEGIA"
     gene            13359..14096
                     /locus_tag="OE968_003864"
     CDS             13359..14096
                     /locus_tag="OE968_003864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCP7221046.1"
                     /translation="MLKLIQTEFLKLRRRKLIWLMLLSALIMPFFALLYFNYFGKTGV
                     EPIKFYKWSAFGYTLWIILPVVLGIFCTMLIHEENQYDMLKQLWIVPISKMGYFFSKF
                     FVVLIYSICFMLITAVASVLFSVLSGYVVFSWASILYLLKKCLEIGVITAFVMLPILA
                     IATSQKGYILPICITLVYAFSGFVIMTINMYLHPLSSMGVIIMRNKDIPGLIFSQEIN
                     VPLAFLCICIWSIVSVLFANIALGRRK"
     gene            14107..14880
                     /locus_tag="OE968_003865"
     CDS             14107..14880
                     /locus_tag="OE968_003865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCP7221047.1"
                     /translation="MWKLLWAECQKIRRSKIVWITVFASIMIAVIVFAGGQDVYNDPD
                     LHYGLKSVYDGSRYIDNAGWYMDAVQPWSTFFVLPAVIALLGSYIICREEEEDTIKSL
                     RLIPINETNLTIAKMIITFIFSILLYLLLFTITFLTESVLHFSDLSTKLVLSCMKEYF
                     LDGIGVFFAISPIIALVSRMKKGYWLALVFTEVYSIAGLFAGMSNVLQTFFPIAAIFN
                     ISGYYITTGEKIMGSIMSLLLCACLSAFILKGLKHNEKN"
     gene            complement(15421..16029)
                     /locus_tag="OE968_003866"
     CDS             complement(15421..16029)
                     /locus_tag="OE968_003866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HCP7221048.1"
                     /translation="MSVINSFILQYGLISVFVLIMIEYACFPLPSEVVLPLCGAIAAR
                     NHFGFLTILILSIIAGILGSIFCYTVGNWGGKSIINKIIEICPKAKKGIFASQDYFNK
                     YSSISVCVCRLIPLCRTYISFIAGIAGQNIITFVISSIVGITIWNTSLISIGYIFSES
                     WVRIMSHYNDYKFLVLIIPISIIFIGFVIKSFIHKKHHKIRL"
BASE COUNT         5245 a         2823 c         2062 g         6105 t
ORIGIN      
        1 attattttat cttcatcata tactttttta atatcttctg gcaactcata attatatttt
       61 gtggatatta aaataatttt atccacatta tccccaatta atggttcaat taatgcactc
      121 ctaattaaac ctccatctaa tttgaaacca tcataaattc cttcttgcac atctttcaca
      181 aattgttctt taaatccaag agttgcgttt ggatttgatg gtaacaaccc actgtatgaa
      241 atgctgataa tggcttcatt acgaggcatt tttgatacat caacaatctt ttctgatact
      301 actttattat caacttcaac ataattaaca taaaagttca tttcttctat attactatca
      361 tctagttccc ttaggttgtc tatagcagga gaattatcca cagtattatt tactattttt
      421 acatttccat tctggatatc ttttatattt gtccacattt tctccaagtt atcaacattc
      481 cctgtgtaca aataatatcc atttattgct cctattgatg tccctgaaat cgaataaaat
      541 ttatttattc ctccatcata caaggcttta actactcctg cttgataagc cccttttgct
      601 cctccacctt ctaaacataa tcctaatttc atagtctcat ctccaaattg tttatcttat
      661 atttatattt caaaaaactt actaaatgtt ttatatatac tatagtggtc ctcaacattt
      721 cctaattctc ttatagaatg cattgctaaa attggacttc ccacatccac agatggtata
      781 tctatatgag tagaagatat tggacctata gtacttcctc ctctttcatc tgacctatta
      841 acaaattctt gatactcaac attagcttct ctacatatat ttttataaat agctatagaa
      901 tatccatcac tagtatacgc ctgactagca tttatcttta taaccggacc ttttcccatt
      961 attggtttat tagttgggtc atgcttttct ggaatgtttg gatgaatagc atgagctaaa
     1021 tctgatgata tcataaaaga tgaataaata gactcaaaga atccctctct atccttaccc
     1081 attgatatac aaattctctc caatatattt aacaacatgt ttgaatctgc accttgttta
     1141 gtagagctac caacttcttc attgtcaaat acagccatta catttacacc atgttgacct
     1201 ttagtattaa caagagcatt caaactagca tgtaccattg caagattatc ttgtctccca
     1261 atagatataa attcatcatt agcccctatt aaacttcctt tttcaaattc atataaaaat
     1321 aaatcaaaat ctataatatc gtccatattt acatctaagt tagatgctat ttgctttata
     1381 agaaaattat ctttttctaa tgtatcattt aacatcccaa ctaaaggtaa catatctttt
     1441 tgcttattat atgaatgacc atcatttata cttctattta aatgtattgc tagatttggt
     1501 attatacaaa ttggcttttt aaagtctata agcctttcat ttggttttaa tatactatca
     1561 ccttttaaaa ctactctacc agctatccca agaggtctat ccaaccatgt acttaatatt
     1621 gctcctccat agcattctgt atttaacttc aaataagatt tttcagcttc tatttctgca
     1681 tttggtttaa tactaaatgt aggagaatct gaatgagagc ctattattct aaatccatct
     1741 ctttctatat cttctgaatt tactacaaaa gctactatag ctgataaatt cttagtaaca
     1801 taatactttc caccaactct tagattccat ctttgattca aaactaattc ttcaaatcca
     1861 tttttatcta agatttcctt agtactcttg actgcatgaa aagacgacgg actatcatat
     1921 atgaagtcta ttaagttttt agcaaagttt atactatcca ttcctcattt acctccatta
     1981 taaaatattt agtgttgtat attctttatt tattttttta attccctgtt ggtcaaaagc
     2041 tatagtaaca tctgtaccaa ttatagaaac cactgtccca accccaaatt taggatgatg
     2101 taccttagaa ccaagtttta tatcatctgg attagtttct ttattagaat cttttattgt
     2161 agcattaact ttatctgcaa ctttagattt gcttatagta ctcatatact ttttagtata
     2221 tttatctaac atattataac ttgctttaga atagcttagt tcttttttta ctttgtacaa
     2281 tctttctata cattcttctg gcagttcttc cataaatctt gaagctattg caacatttgt
     2341 tttaccatat aatgttctct tctctgtcaa tgacatatat agctcttctt tagctctagt
     2401 tataccaaca taacaaagtc ttctctcttc ttctatttgt gaatcactca tagattttat
     2461 agctcttgat ataggaaata acccttcttc catacctgtt aaaaacacaa cagggaactc
     2521 taaaccttta gatgtatgaa ttgtcataag cgaaacccta tcattgtctt cttcatcatt
     2581 tgattcagat gtaagtgcta tacttgttag gaatgtctct aagtctttat tttcataagt
     2641 atcatcatta ctactttcaa actccaaagc tatagaaata aattctctca aattatcaat
     2701 tctgtcttga gcttcttcac ctttgcctgt taaatctttt tcatttttat ttcttatctc
     2761 tacaagctcg tccatatatc ctgtagtgtc caagactttt tctataagtt tgctaacagg
     2821 ataaacttct tttatagttc taagagtccc tataatatca acaaatccac ttatacttgc
     2881 ccttgcctta gtagatatat ctgaatttgt ttctatatca attaatactg agtatatact
     2941 ttcctgtttt aagttagctc tatcttcaat tttttctatg gttctaagcc ctatacctct
     3001 tctaggaaca tttataatcc tttttataga tatatcatct tgtggatttt gaataactct
     3061 taaatacgcc aacaaatcct ttatttcttt tctctcatag aattttgtac caccatatat
     3121 attgtatgga atttgacttc tatttaaagc gtcctctaca ggtcttgcct gtgcatttgc
     3181 tctataaagt actgcaaaat ccttataagg tctattttct tttctagcta tttgtgcaat
     3241 tgaatcagca atgaaatcag cctcttctat ttcactacca gttaattgta tctttataag
     3301 ttctccttct tttttttcac tccaaagctt ttttcttttt ctttctatat tattagatat
     3361 aactttatta gctgcatcta atatcacttg tgtagaccta taattttgtt ccaactttac
     3421 aacatgtaca ttgtcataat ctttctcaaa ttcaagtatg tttcttatat ctgcacctct
     3481 ccatccataa atactttggt catcatctcc aacaacacaa atattttgat gttctcttgc
     3541 taataatttt atcaattcat attgagcttt acttgtatct tggtactcat ctaccattat
     3601 gtatctaaat ctacttctgt aatatgctaa cacttcatca ttagccttga aaagttctac
     3661 agttttaagt attaaatcat caaagtcaag tgcactattt ctttttaaac ggtcttgata
     3721 tagcgcataa atatctgcaa tcttaaccat tctattatct gccatattga tatctttaaa
     3781 ctgctttgga gtataaagtt tatcttttgc tcctgaaatt gcacttataa ctgcttttgg
     3841 ttcaaacact ttatcactta aatttaattc ttttagacag tctttaacca atgtaacttg
     3901 gtctgctgaa tcataaatta caaaacttct attgtaacca atcttattta tatcttttct
     3961 tagtatacga acacagcaag aatggaatgt acttatccac atatccttag tttcaggacc
     4021 tatattttgt tcaactctct ctctcatttc atttgcagct ttgtttgtaa atgttatagc
     4081 taatatattt ggtgcttgta cacctttatc ttctataaga tatgctattc ttgttgttaa
     4141 taccttagtt ttacctgaac cagcaccagc cagtataagt actggacctt cagtcttttc
     4201 tactgcttct ctttgagcag gatttaatgt atctaaattc atatttctcc tcctgttaac
     4261 agccataaat atattttaat ctaaaatatg aattacttca aattataatt atgtattata
     4321 ttaatagatt atttccaata tattacaatt aaataacatt tttccatata atttatttca
     4381 ttgtttaata aaaaaaataa ccttatgatt tggggaatca taaggcacct ttaaggggtc
     4441 taggttaagg gttattatat ataaatctat ttttttaaaa taggtttagg gcttaattat
     4501 ttatttgtat taagttctct ttccttccaa tacttataca aatcttcttc tttcttaaat
     4561 aagggtaaat tcatatttct atgtactttt actaaccatg gggattctag gccagcttgt
     4621 ataatattat tttcatttat aaacacattt tctgcttttc cttcatcaat caaaatcccc
     4681 ttatccaata catatatgta atcacatatt tcatacatta aattcatatc atgactggat
     4741 attactattt ttatattatt tttatttaat ccctttatta tatctacaat agacctagta
     4801 cttactgggt ctaaaccagc tgtaggttca tcaagtaata caatttcatt ttccattgct
     4861 ataactgatg ctattgccac tctttttttc tgtccatagc taagaaaatg tactggcctg
     4921 tctataaaat ctattccatt aacagctact agagctttgt ttattctctc tttaattgtt
     4981 ttttcatcca taccaatgtt tctcattgca aaggctatat catcatatac ttttgaataa
     5041 aaaatttgtt tttctgggtc ttggaacaca atacctacat tttttctaag gttgtataaa
     5101 cttctcttat catattttaa cttttcttct ttaaaaagaa tttctccaga tgtaggcttt
     5161 aatataccca ttaaattcat aaataatgtt gattttcctg aaccatttga acctattata
     5221 cctataacat ttccctttga aaaatccata ttaatgttta atagtgcatt ggtatttttt
     5281 tcatattgat acgttaaatt atttatttta aacatcatta tcccctacta tgtgaaattt
     5341 accatcatac aattttatgt ctaatgatat acacatatca tcataccttg tcataagtct
     5401 tttgtacagc atacttccaa gaatacctaa ggatttatat gaagttttta aatttatata
     5461 tccaaatctt agctcttgtg acttgtatat ttctgaaaat tcttctaaaa atatgaatat
     5521 aaacctatat attaacattg ataactcgac aaaagtgtca ggtaaatgaa gttttttaaa
     5581 aaagaatatt aattgattaa aaggtgttgt aagtatacaa aaatacacac aagtcaaaca
     5641 agacatcgct ctaaataaca catgaataga catgtcaata gacgcctttg atattcctac
     5701 attaaaacta aaaaattcaa aactatataa taaatctgct ttattaaaag atatatttac
     5761 aagagttatt cctatactaa gaaataaaaa gtacattggt attctaagta attttaaata
     5821 attttttaaa tctattccag ccacacaaac aaccaaaata ctcattaaaa tcataattcc
     5881 acttaaaata aatatatttt gtattaccat agaagcaatc agaaaaatta ctcctatggc
     5941 tacttttttg tttggattta ctttactcaa tctatttgta tatgcatatt tatcaattat
     6001 aagcatgatt aacttctctt tcctttttga agacctaata tgtatcctat tacaccagcc
     6061 cctaaagctg cttgtgcaga gaataataaa ctttctattt ctccacttgg tggctcatat
     6121 ggactgctaa accatggttt gtaatttgga tttatcttag taatttcact ttcagcttga
     6181 ccatctgctc ctccatattc agcacctgag ttgacaagta atgggaatat aataagagct
     6241 actactaata aaagtaataa tatgttagtt tttgttttag cactcattag ctttaactcc
     6301 tttatcatta ttttctagta tgcttttttc tccgttttct gtaattaaat tatatacaat
     6361 tacagtaagt ataccttctg ctattgctat tggtatttga gtcataaaga aaattcctaa
     6421 aaatttaatt gctgaagcca ttaccccacc tgatgggtct gggaaagcca gtgctaattg
     6481 tattgaagtt attgtatatg tggctaagtc tcctattgct gctgcaagaa atactggaat
     6541 agcattattt ccatcttttt tctttaaagc cttaaatatt aggaatgata cgattggccc
     6601 tattatcgcc attgaaaaag cattagctcc taaagtagtt attcctccat gtgctaataa
     6661 caatgcttgg aatattaaaa ctatagttcc aagaacaaac attacgcttg gtccaaacat
     6721 tattgctcca agacctacac cagtaggatg tgaacaactt cctgttactg aaggtatttt
     6781 tagtgctgat aatacaaaca caaatgctcc acataaagct aataatactt tctttttagg
     6841 gtcttgcttt actattttac ctattgattt taatccgaat aagaaaaatg gtataaatat
     6901 aactccccat gctatagacc attttactgg taagtaacct tccattatat gcattgcatt
     6961 tgatgtaact ggagttaaaa tgattaacat aagtgcagct ataaccccta atttaatatt
     7021 ctgtttcatc ttagtatccc tctctccctt tctaataatt aaaacataat aatacatgtc
     7081 tgatttattt aataaaataa aaaagcctaa ctcgatggtt aggcttctaa ttttccacaa
     7141 tctaaataca aacacataaa acaaacatat ctgtataatt attataagaa actttctcca
     7201 tccccgaaga aattacttta atattttagg caggtctcct gacttagctt catcctactc
     7261 ctcttccttc ccatgagata taaaaaatat catcatagtg gctaacaaaa gtttcgtctg
     7321 catcacagta gcgggggctg taaaggaatt taaccttttt ccctattaat cttgcttaaa
     7381 gaacctataa tattatatat ttaattttta aattcttctt aaattatttt ctatataaat
     7441 cattgtatac cttttctgtg aaaatttcta cattttttat aaattttatt catttttata
     7501 tttttatgta tataaattct tttttgtaag tttattaatt tctaattatc ttctttaaat
     7561 acattgaaac tacatcagaa aatctagtta tatctcttga atatataaaa tcatttccat
     7621 atattaatct ttcagcttca agttctgatt cttttcctgt aaatactcct aatactaata
     7681 tattttgctt tctagctttt ctcacttcat tggctgtatc tctcaaacca actatacccc
     7741 tataagcctt ttctcctctt aatgttctct cactactttt tcctatcttt acatcatttg
     7801 gtcttccatc actgagaact atcaggattt tattttcttc atctctattt attagaccac
     7861 tacatataga ttttattgcc aaaccatctc tattattacc agcacaaaaa tattcaaata
     7921 tattttcact attttttata ctatcatcat aatctttaaa tctttttaat attgtatagt
     7981 ctaaaaaact agaaaatccc atcactctat ttggtatgcc aacttctgtt agagcatttg
     8041 caattatgta agcttgaatt gccacatttc cctgatttct actttgagag ccacttgcat
     8101 ccaataatat atcaataacg tatttccctt tttcattttc tatatcttta taaaatattt
     8161 tattattatt acttctacca actctccaag ctctattggc taatatagta ccacaatcag
     8221 aatatactct acttttagca ttttcttcta ttaaaattct tgatagactt tcttttaatc
     8281 tctttatttg ctgtctatac attctagcat gttctctaaa ttttcctaaa ttattttctt
     8341 tttgtcttgt tacatatttt agttgaaata cattattaca ctcacttcta agaactccat
     8401 ctgtaaagtg tattctacaa ccttcatgaa catttctaca attttgtgtc tcaatttttt
     8461 taatttcacc tttactcaaa taagtttttc cataataatg ttctattttt gaatatatct
     8521 tatttgcagt gtcttcatca acatatataa ctcggtctgc tgaattgcta catttagaat
     8581 catcaaaatc ccctacacct tctacaagca tggatgaaga tattgaatct atatcacttt
     8641 caataatatt ttcttcttca tcactataaa gttcttcata catgaaatca gcaaatgtat
     8701 caaaatttac ttctacactt tctacattat tttcatcaat aagactattt tcttctccat
     8761 ttaatatgta ttcaaaataa gttaaatata taacatctaa tgcttttaaa atctccataa
     8821 tatcttgatt ggtatctata tttcttatat cattaactat tcttctagtc atactatcta
     8881 atgctgggtg cttgtccata ctataaagta caaatgtgta tttaatttta tccataatat
     8941 tatcattgtg tattttggta aaacgtgaaa caatatcttt ataagcattt cttcttatgt
     9001 cttctatccc tggcctatct ttaatgacct tttcttcaac tattgtattt aatataactt
     9061 gaattagacc cagtataata tctttgttgt atccttttct tattctattt gtaagatatt
     9121 ttttaactat atcccaatct acatactttc ttctagcacc tgcaattatt gcaaaatata
     9181 gacctatttc ttttgaagag taatcttttt ctgatatatc tatactttca ttgtaatcac
     9241 cagctattgt ccatgataag ttattagctc tattttcaaa ttcataatca tcatatatcc
     9301 atttcataat ctcacctata ttaaatatga cttattggaa acacatctat actctcccat
     9361 ttattaggta ttctagtttt aattacatct ccaaccattt ctttctcata tacatcaaaa
     9421 gtctttcctg taagtcccat attaattgca agagttggtt ttaatcctct tcttatagtc
     9481 ttaagagatg ccataagacc acgtaaatca atagctttac tagatatctc tccattttga
     9541 gacttcaatt gtaaatctaa aaatattcct gcaaagtgta ttagtttttc ttcatcagca
     9601 tctgaaaatt cattttttaa aatcatcatt aacttatctt cttctatagg aggaatatct
     9661 attaccataa atctagatac cagtgcttca ttaagttctt ttgttcctgc atattcataa
     9721 ttcatagtcc caataaatct tgttgctgga tgtagattga ctctctcata cccaggtaca
     9781 tcaattattc ttctatagtc taaagctgaa tgtaccacaa ctatagcatc attttttgcc
     9841 atattaattt catcaaacac cccaaaacct ccattaatag cacactcata aactgagcct
     9901 cttctaagtt taacttcatt gtctataaat gtatctgtac ctataagtgt tgaactgtct
     9961 gtatttatat gaaatgatgt attccactga ggtctattaa atatttcccc tagattatca
    10021 gcaagtaagt tttttcccgt tgcctttggt cccgataata atatattttc ttcttctaaa
    10081 atagctgcta tacacataga caagatatct ttaccataaa aataagtttt agactttgtt
    10141 actctgtatt ctaaatcttt ttctaatcca taataatttc taaaatacag tacatcttca
    10201 ataagttttt catctacccc ttgcaccctt agattatcta ttatatccat atttttaccc
    10261 cttttatata aatagtattt gtttcatttc ttatcaccat tttagcataa aaggatataa
    10321 gctaaaattg attttttaat ctcccccatt ttaagtaaaa ccatgcacca ttttatcact
    10381 acaaaattaa gagtactact tactgatatt tcttgatttt attcgtctat acgtatataa
    10441 tatatactga taaattatga ggaaaggatg attgaaatat ggaatatatg tcttgcccag
    10501 aagtagcaaa aaaatggggt atttctgaaa gaagagtaca aaaactatgt gaagaaagtc
    10561 gcataccagg agtttcaaaa ctcgggtata tgtggctgat accaaagaac gcagaaaagc
    10621 ctgttgatgg tagaacaaaa agaagaaagg aagtacaata tgaatagcgt tttgattata
    10681 gatgatgaca aagaactttg tgctcttatg aaaaaatgtg ttgagcaaga aaatttatct
    10741 gctattactg cacatggtgg tgcagaaggt ctacatttag tcgataaaaa tagacacaca
    10801 ctctctcttg taattttgga cataatgatg ccagatatag acggttttca agttctgaaa
    10861 aaaattagag aaacaagtaa tattccagta attatgctta ctgctaaaaa tgacgaggat
    10921 gataaagttt ccggactacg tttaggtgct gacgattacc taacaaaacc gttcagcata
    10981 aacgaactta tggctcgtgt caattctctt attcgtcggt atactatgct aaaccctgct
    11041 tttataacag acacagattt cataataata aatggcatga ttattgacaa gacaaaccga
    11101 attgtttctg tcaataatat tcctgttcaa cttacaagca aagaatttga tttacttgct
    11161 tttctggctt ctaataaggg acgggtgttt accaaaaaac agatttatac acaagtatgg
    11221 gaagaagaat atgcttttga cgatagtaac atcatgtctt tcatcagtaa attgagaaaa
    11281 aagattgaac cagaccccaa ccatccattt tatattttga cagttcgtgg tgtcggttat
    11341 cgttttaata aggaggctta acatgaatac aagtgtctat ctgcttttga tattggctct
    11401 tagcctgatt attatagcgt accttgtttc tgtcctgcta cgtgtccgaa tacaacttac
    11461 acttataaaa gatgctttag aggatataaa aaatggaaac cttaatcgac gtattttaac
    11521 agatgaaaac gacattacaa aacaaatttg ctatgatatt aacgaaatag caatcaatag
    11581 ccaatttcaa cttattcagc aaaaacaatc agaacaagcc tacaaacagc taatgacaag
    11641 tctctcccat gatgtaaaaa ctccacttgc ttctttggtc ggttatttgg aagcagtaga
    11701 aagtaaaatt gttgtaggag aggaaaaaga cgagtatatc catgttgcgt ctaataaggc
    11761 tcattactta aagaattttg tagaaaatct atttgaatgg gtaaaattgg attctaagga
    11821 acaagttttt cattttgata tttttgactt gaatgaatta tcccgtaata ttatatctga
    11881 ttggatacct gttttagaaa gcagtcattt tgaatatgaa tttgatatac cagaaataga
    11941 gtacttctta cgtatagacg caaatgcata tacccgtatc attaataacc tattacaaaa
    12001 tattattacc catagtagtg gaaacaaaat gacattgaga atttttgaaa acaaagagca
    12061 agctcaaatt ataataacag ataatgggaa aggtatatct tcagacaatc tcccacatat
    12121 ttttgaaagg ttgtaccaat gcgaccattc acgagcttca aagggaaatg gtttaggctt
    12181 ggcgattgca aaggaactta ttaacgctca taagggaaat attaccgcca acagcactcc
    12241 cggtatggga acagaattta caatattgct tcctaaagcc ctgtaaaagt acgaggcttt
    12301 cttactctaa aacaagataa aagcaagatt atggcaaggt tttggcaagg ttcatgtttt
    12361 ataattctaa ttgtagttga ttttgacgtt gtatcaacta tcttttgtag aaacaaattt
    12421 attaaaagtg aggaaattat atatgaatga ttttgtgatt gaaacaaagc aacttacaaa
    12481 aatttatggg aatcaaacag tagttgacaa agtcaatctc catgtaaaaa aaggccgaat
    12541 atatggtctg ttaggacgca acggagctgg gaaaaccaca attatgaaaa tgattttagg
    12601 attgacttca atcacgtatg gcgaggtaga tgtatttgga gagaatatta agggacgtga
    12661 aaaacaagta tatccccgta tcggtgcaat tatcgaaacg ccaggatttt atcctaatct
    12721 gacaggaacg gagaacttgg agatttttgc aaaactgcgt ggtacagccg cccctaattc
    12781 tgtaaaaaga gcattggaaa ttgtaggctt accttataaa aataaaaagc tgtttagtaa
    12841 atattcactt ggcatgaaac agcgacttgg tattgccaac gctatcctgc atgacccaga
    12901 actgttagtt ttagatgagc caaccaatgg tcttgaccct attggtattg cggagatgag
    12961 aaagtttatt agggacttga gcgttgagca tggaaagaca attcttattt ccagtcatat
    13021 tctttcagaa atctcattgt tggctgatga tattggaatt atcgaccacg gtgttctttt
    13081 ggaagaaagt agtatgagtg aactagaaaa gaaaaacagt aaatatatcc tgctacaagt
    13141 ttcagatatt ccgaagacat cacttatttt agagcgtcaa tttaacacga aggattattc
    13201 cgttcaagat gactacacgt tacaccttta taacactaat ctggatatgg gtgaaatcaa
    13261 taaagcactt gtaatgcaga atgtaactgt tattagttct caactttgta atgatacttt
    13321 agaggactac tttaaaaaaa tcacaggagg agagggcatt gcttaaactt attcaaacag
    13381 aatttcttaa actgcgtcgt aggaaactta tttggctgat gttgttgtct gctctcatta
    13441 tgccgttttt cgcactacta tacttcaatt attttggtaa aacaggtgtt gagccaataa
    13501 agttttataa atggtctgca tttggttata cactttggat tattttgcct gttgttttgg
    13561 gtatattttg caccatgctt atacacgaag aaaaccagta tgatatgctc aaacagcttt
    13621 ggattgtacc tattagtaaa atgggatact tttttagtaa atttttcgtt gttttgattt
    13681 actctatttg ttttatgctg attacagccg ttgcttctgt gttatttagt gtactttctg
    13741 gatatgtcgt atttagctgg gcaagcattt tatatttgtt gaaaaaatgt ttagaaattg
    13801 gtgtaatcac tgcttttgta atgttgccga ttttggcaat cgctacatct caaaaaggat
    13861 acattctccc aatttgtatc acattggtat atgccttttc cggttttgtt ataatgacaa
    13921 taaatatgta tttacaccca ttatccagta tgggagttat tatcatgaga aataaagaca
    13981 ttccaggtct tatattttca caggaaatta atgtcccatt agcatttctt tgtatttgta
    14041 tttggagtat tgtatcagta ttgtttgcaa atattgcact aggaagaaga aagtgaggtg
    14101 tagataatgt ggaaattact ttgggctgaa tgtcaaaaaa ttcgtcgttc aaaaattgtt
    14161 tggattacag tttttgcatc cattatgata gcagtcatag tttttgcagg ggggcaggat
    14221 gtatataatg acccagattt acattatggc ttaaagagcg tttatgacgg ttcacggtat
    14281 atagacaatg caggttggta tatggacgca gtacaacctt ggtcaacttt ttttgttctt
    14341 cctgctgtca ttgccctatt aggaagctat attatttgtc gtgaagaaga ggaggacact
    14401 attaaatccc tgcgtcttat tcccataaat gaaacaaatt taaccatagc aaaaatgatt
    14461 attactttta tattcagtat acttctttat ttgttactct ttactataac atttttgact
    14521 gaatccgttt tacatttttc cgatttatcg acaaaattgg ttttaagttg catgaaagag
    14581 tattttcttg atggcatagg tgtattcttt gcaatttctc ccattattgc cttggtatcg
    14641 cgcatgaaaa aaggatattg gcttgcatta gtattcacag aagtttattc tattgctgga
    14701 ctatttgcgg gtatgtcaaa tgtcttacaa accttttttc ctattgcggc aatatttaat
    14761 atttctggat actatataac tactggagaa aaaattatgg ggagtatcat gagtttatta
    14821 ctttgtgcct gcctttctgc atttatactt aaagggctaa aacacaatga aaaaaattga
    14881 aataggtata tcaaaatgaa aaagataaaa aaactgatta ttctaattgt attcttgttt
    14941 ctttttggca tgttacactg ttatactgaa tggaaattca acaataaccc acctaaaggg
    15001 gtaatagaaa gaataaatga gtggactgat aagattggac tggattagta acttatgtta
    15061 attatagtga atgtaatatt agcaagttat tgtttcgtat tttaatacta taactttaaa
    15121 tatttggttt taatcttcca aacgaatata aaaaaactgt cacagaggca acatattttt
    15181 gaatatttat aaagtggtag ttttgatttt caaagctacc gccttttctt ctatataagc
    15241 aaacttatcc tcaacaaagt gtaaaacatg gtgcatttta agaaaaaagt accacagaca
    15301 caagcaataa aagaaacgcc gagaacctac aaaaacgtag tgcttatgca gatttacgac
    15361 gccttctatt ttctcaaccg tcttaatgac cttgtacaaa agaaattttt ctaatatttt
    15421 ttataatctt atcttgtgat gttttttatg tataaatgac ttaataacaa atccaataaa
    15481 aattatggat attggtataa ttagaacgag gaatttataa tcattataat gtgacattat
    15541 tcttacccaa ctctcagaaa aaatatatcc tatactgatt aatgaagtat tccatatggt
    15601 tattcccacg atagatgata ttacaaaagt tataatattt tgacctgcta tacctgctat
    15661 aaaagatatg tatgttctac ataaagggat taatctacat acacaaacag aaatagaaga
    15721 gtatttatta aaataatctt gagatgcaaa tattcctttc tttgcctttg gacatatctc
    15781 tattatttta tttatgatag atttacctcc ccaatttccc actgtataac aaaatatcga
    15841 accaagtata cctgcaatta tacttaaaat taaaattgtc agaaatccaa aatgatttct
    15901 tgcagcaatt gctccacata aaggtaaaac aacttcgcta ggtaatggaa aacaagcata
    15961 ctcaatcata attaatacaa atacagagat taatccatat tgtaaaataa aactattgat
    16021 tacagacact tacttatcta tctcctttct tatttaaagg ttttaagggt acatgttcta
    16081 aggattctca ccctatattt aaagaatcaa tctctttaaa ctattatatg tatttacaca
    16141 aagcatttat aacatacttt aaaaatagta ccttaaaata agaaacttaa taaataaaaa
    16201 aagattacgt ggctacgtcc tactctccca ggcag
//
LOCUS       DAJMZY010000273        10968 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.guided.122, whole genome shotgun sequence.
ACCESSION   DAJMZY010000273 DAJMZY010000000
VERSION     DAJMZY010000273.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10968)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10968)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10968
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.guided.122"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            <1..294
                     /locus_tag="OE968_003867"
     CDS             <1..294
                     /locus_tag="OE968_003867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HCP7221049.1"
                     /translation="LGAKDILEDGKIHDDYRIDYLRSHINACKLAIEDGVEMIGYCPW
                     SFTDLLSSSQGFNKRYGLVYINRTDHEILDLKRIKKDSFYWYKEVIENNGIVK"
     gene            322..1170
                     /locus_tag="OE968_003868"
     CDS             322..1170
                     /locus_tag="OE968_003868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HCP7221050.1"
                     /translation="MYITKVLNNSLLLAKDDNDEEIILMGKGIGHNYKAGSELNEKDI
                     EKIFVLHDENIKKSIIQLATEIDAEYFGIAQMIIAYGIEKYNLKLMNHIYLALTDHIA
                     FAVRRFKEGIMIENHYLFEIKEFNPKEYDIGKYAITVFKEVLGLDLPEEEIGNIAGHF
                     INAQQDNPYSDRNKRSAKIVNAILQIVHYHFSIVYNKESFYYRRFVMHLKAFSQRFLA
                     NEPSREKIDFIYEQVQKNCKEEYECVKKVGAYMYKEYSRELPRQEELYLMIHIHKILG
                     ELCENS"
     gene            1672..2364
                     /locus_tag="OE968_003869"
     CDS             1672..2364
                     /locus_tag="OE968_003869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003020373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCP7221051.1"
                     /translation="MNKVLIIDDDKDLCILLKKSISIEQIEANYCHSGRDGLVELSKQ
                     DYQLVVLDVMMPGMDGFETMEQIRKYSSIPILMLTSKSDNYSKVHGLRAGADDYLTKP
                     FEITEFTARVLSLIRRYTRFNPKNEEPQQLSFKGLLIDLDQHTVTTNGEPMLLPPKEF
                     GVLLYCARHQGKILTKQQIYEAVWGEPYVYDDSNIMAIISRLRKKIELDPSSPIYLQT
                     IKGIGYQFNTEV"
     gene            2361..3296
                     /locus_tag="OE968_003870"
     CDS             2361..3296
                     /locus_tag="OE968_003870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HCP7221052.1"
                     /translation="MKMDEQTIILFLLLLSIGLLFLSIFAFSKLGHIHKRLKDIEEIL
                     ADVQIGDENRKILIKPCDVMAPLVYQLNEIVYDYENKLLSLKKSDKASKQLMTSLSHD
                     VRTPLTTLIGYLDAVHSGIVIEQEREEYLEIARRRAYDLKDYIDVLFDWFRLNSDEFT
                     LSIESVEIAELSRNILKDWIPIFHEKKLNFEIDIPENRLMVNLDPDGYSRVVNNLVQN
                     VLAHSKARQIKITMSEDSRMVLLRVEDDGVGIARENLPHIFERLYKCDKGRSEKGSGL
                     GLSIVSQMVERMGGQVSVESEIGKYTVFTVSLPLI"
     gene            3444..4367
                     /locus_tag="OE968_003871"
     CDS             3444..4367
                     /locus_tag="OE968_003871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013273760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCP7221053.1"
                     /translation="MNNLIIETKNLTKQYGAQKSVSNLNIHVQKGRIYGLLGRNGAGK
                     TTTMKMLLGLTKPTTGEIKIFGQDIHNNEKKLLPRIGCLIESPGFYPNLTGTENLKIF
                     ARLRGIPKKNAVESALDVVGLPNNDKKLFSQYSLGMKQRLAIALAIMHDPQLLILDEP
                     INGLDPIGIAEVRTFIRDLCTERGKTILISSHILSEIALLADDIGIIDHGILLEEESL
                     AQLEEKNSKYIHFAVSDAAQAARLLETQLNLKNFKVADNYNIMLYDTDVSVAEINRAF
                     ILNNIEVSESHLCEDTLEDYFKKVTGGEGIA"
     gene            4351..5121
                     /locus_tag="OE968_003872"
     CDS             4351..5121
                     /locus_tag="OE968_003872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCP7221054.1"
                     /translation="MKELLDIISCEFSKLKRLKFILISILGACLFPIPATILIAKDNL
                     PFEQLFKLVVNFGYFLLLPIVLSIVASQLFFIERDNDVLKNLATVPVPKGKLALAKLA
                     VLLFISLFYSVAGLGATIIGGFIVGIVEGVAVKLGMSIAFGIMFFVTVLPVVVLIVYF
                     NRSYIFSIILSFVYAIFNFSISLNIINFEPNNPLLSVLPAPVIMRWWMAFWGDPTGEY
                     TVLRQPYLLSTPACVGILCLITIIAVLLICMIYKKQEN"
     gene            5131..5913
                     /locus_tag="OE968_003873"
     CDS             5131..5913
                     /locus_tag="OE968_003873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCP7221055.1"
                     /translation="MLDIITTEFQKIKRYNILWIGVVAVLFSALLAVFQVVSSHGSDP
                     LTYESFANGVIWNNFSLSFPFGITLIGGYLINREYTDQTLKNILTVPISLRKLLVGKL
                     IAVGGITVLLSLFSFLCTFILGLLFCNINISVILVVKSLVQILSVNLYCYVAVLPIIA
                     YFGRKQNAFLTGVGIAFVYGFCGVFVAGRNLTDFYPITAGLGLVGYNNGAGTVYQPLI
                     GAMTLIVILILTTILLVFTPNYDKVMTISKKKGIKHKKYSHK"
     gene            6290..6826
                     /locus_tag="OE968_003874"
     CDS             6290..6826
                     /locus_tag="OE968_003874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rubrerythrin family protein"
                     /protein_id="HCP7221056.1"
                     /translation="MNLKGTKTEKNLMAGFAGESEARNKYTYYASKARKEGYNQIAAI
                     FEETANNEKEHAKLWFKLLHDGMPSTEENLKDAAAGENYEWTDMYAKFAKEAREEGFD
                     KIAYLFEAVGKIEKEHEERYLKLLENLNEGKIFKRDEEVVWQCQNCGHVYVGTEAPEK
                     CPVCDHPKAYFNIKAENY"
     gene            6858..7247
                     /locus_tag="OE968_003875"
     CDS             6858..7247
                     /locus_tag="OE968_003875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HCP7221057.1"
                     /translation="MKFSKQRELILNEILNNPVHPTADYLYENLKKDNPNLSLGTVYR
                     NLAQLTEHGFIRKVSIPGYPDRFDGRIDNHYHIICEVCGEVYDLESEVLNNLQELISE
                     ETDIKITSYNISFKGICNNCKRCSQVG"
     gene            7284..7670
                     /locus_tag="OE968_003876"
     CDS             7284..7670
                     /locus_tag="OE968_003876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="desulfoferrodoxin"
                     /protein_id="HCP7221058.1"
                     /translation="MCSEQKFFICETCGNLVGMIQSGGVPIFCCGKPMKELVPNTTDA
                     AVEKHVPVIEVDGNNVTVKVSSTTHPMTKEHHIAWVYLMTEQGGQRKCLAVDGEPVVK
                     FALNDDDKVISAYAYCNLHGLWKAEL"
     gene            7797..9239
                     /locus_tag="OE968_003877"
     CDS             7797..9239
                     /locus_tag="OE968_003877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HCP7221059.1"
                     /translation="MSIYKCSVCGYIYDESKNDKTWDELSEDWECPVCTKGRSYFGKI
                     STVYYEEDEKIAEDIVEDESKLNTEKEGDLNYLSTYLRRDDEVEKHMDIIHEMAVTGK
                     SIIEPMRTKLPVISWDDILIMGAQLNPLPLNEHDEVNTTTIIGKKAKKPMIIENPVYI
                     SHMSFGALSKELKIALAKGAAQNKTAMCSGEGGILPEEKEASYKYIFEYVPNKYSVTE
                     ENLKNSDAIEIKIGQGTKPGMGGHLPGEKVTEEIAKVRNKPVGQDVISPSCFEEIQSK
                     EDLKKLVDELREVSEGRPIGVKISAGHIEKDMEFIAYAKPDFVTIDGRGGATGASPKL
                     LKDATSIPTIFALYRARKYIDTHGLDIDLVITGGLRISTDFAKAIAMGADAVAIASSA
                     LMAAACQQYRICGSGKCPVGVATQDEELRKRLHIENSANRVANFLNVSLEELKTFARI
                     SGHKDIHDLSVDDLYTVNSEISNYTNIQHV"
     gene            9536..10351
                     /locus_tag="OE968_003878"
     CDS             9536..10351
                     /locus_tag="OE968_003878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HCP7221060.1"
                     /translation="MERLKIQVLVDNNTYIDRYFVGEPAVSYYIEIDGNRILFDSGYS
                     DVFISNAEKLNIDLGNLTHVVFSHGHNDHTRGIQFLENRYDLSTVELISHPNCFIPRK
                     HGEKSIGAPFSAEEIKNIFMYNPKDKPFNLSKNCVFLGEIPSINDFEKRAKIGKCKIG
                     DLWEDDYVLDDSAIVCKTDKGIFIVTGCSHSGICNIVEYAKKVCGDDRVIGILGGFHL
                     FELNNRLDSTIQYLDKEEIRMLYPCHCVSFKVKAKMNEILNINEVGVGLTISI"
BASE COUNT         3967 a         1345 c         2044 g         3612 t
ORIGIN      
        1 ctaggagcta aagatatatt agaagatgga aaaattcatg atgactatcg tatagactat
       61 ttaagaagtc atataaatgc atgtaaacta gctattgaag atggtgtaga gatgattgga
      121 tattgtccat ggtcatttac agacctttta agttcttctc aaggttttaa taagcgttat
      181 ggacttgttt atataaatag aactgaccat gaaattttag atttaaaaag aatcaagaaa
      241 gatagttttt actggtataa agaagttata gagaacaatg gaatagtaaa ataaacataa
      301 atatatattg agggttttag tatgtacatt acaaaggtat taaataattc gttgctactt
      361 gcaaaggatg ataatgatga agaaataata ttgatgggga aaggcattgg ccataattat
      421 aaggccgggt ctgagttaaa tgaaaaagat atagaaaaga tttttgttct tcatgatgaa
      481 aatataaaaa agagtattat acaattggca acagaaatag atgcagaata ttttggtata
      541 gctcaaatga taattgcata tggaatagaa aaatataact taaaacttat gaaccatata
      601 tatttggcct taactgacca cattgccttt gcagtgagac gttttaaaga aggtataatg
      661 attgaaaatc actatttgtt cgaaatcaag gaatttaatc caaaagagta tgatatagga
      721 aaatatgcta ttactgtttt taaggaggtt cttggtttag acctaccaga agaagagatt
      781 ggtaatatag caggccattt tataaatgca caacaagata atccttatag tgatagaaat
      841 aagagaagtg ctaaaattgt aaatgctatt ttgcaaatag ttcattatca cttttctatt
      901 gtatataata aagagtcatt ttattatagg agatttgtaa tgcatctaaa ggccttttca
      961 caaagatttc tggctaatga accatcaaga gaaaaaatag attttatata tgagcaagtt
     1021 caaaaaaatt gtaaggaaga gtatgaatgt gtgaaaaagg taggagctta tatgtataag
     1081 gaatactcca gagaattacc aagacaagag gagttatatt tgatgattca tattcataag
     1141 attttaggag aattatgcga aaatagttag aatatcttaa tatgctagta atattataaa
     1201 aaattaaaaa ttaactgcac tttaaatatg aataattgca ttacttaagg gggttgtctt
     1261 aaaattgatt tttttaatta aatttgaagc tcaactcctt ttttaaacct ttatatcatt
     1321 acaactttaa tgtttatacg cctgtacttc agatgtatat ctacttttta catttctcaa
     1381 catgcaaatc taccattctg tatatagtaa atgtattatc atgtttgttt tattcaagca
     1441 cacttataat acgcttgatt ttttcacaat gatgaaatat actaatgggt gttataggta
     1501 taagaatcgc attacacttg aagaagtaag tgataaatga gatataaatc ctcatatgat
     1561 aaactactat ttcattgagg aacatattct aagtgatgtc aagatactac aatatgacta
     1621 aattcctagt gataaaaaag tctacgaatg agtgtagaaa ggggaactaa gatgaataaa
     1681 gttttaatta tagatgatga taaagatctt tgtattttgt taaaaaagag tatttcaatt
     1741 gaacagattg aagcaaacta ttgccattct gggagagatg gactggttga actttcaaaa
     1801 caagattatc agttagtagt tctagatgtg atgatgccag gtatggatgg ttttgaaact
     1861 atggaacaaa tacgaaaata tagcagtatt cctatcttaa tgctgacatc aaaaagtgat
     1921 aattacagca aagtgcatgg attgcgagct ggtgcagatg actatctaac caaaccattt
     1981 gaaattacag aatttactgc tcgtgtactg tctttaatcc gacgttacac ccgttttaat
     2041 ccaaaaaatg aggagccaca gcaactttct ttcaaaggtt tgttgattga ccttgaccag
     2101 catacagtta ctaccaatgg cgaacctatg ttgcttccac ccaaggaatt tggtgtactt
     2161 ctttactgtg caaggcatca gggtaagatt ttgacaaaac agcagattta tgaagccgtg
     2221 tggggtgagc catatgtata tgatgacagc aatatcatgg ctattatcag tcgcctaaga
     2281 aaaaaaattg aactagaccc atcatctccc atctatttgc aaacaataaa aggaattggg
     2341 tatcaattca acacggaggt atgaaaatgg atgaacaaac gataattctt ttcttactct
     2401 tgctgtcgat tggtctactt tttctttcca tatttgcttt ttccaagctt gggcatattc
     2461 acaaacgctt aaaagatata gaggagatac tcgctgatgt acaaattgga gacgaaaatc
     2521 gtaaaatact aattaagcca tgtgatgtta tggctccatt ggtttatcag cttaatgaga
     2581 ttgtctacga ttatgaaaat aagttacttt ctctgaaaaa gtcggataaa gctagcaaac
     2641 aacttatgac aagtttatct catgatgttc gtacaccatt aacaactctg attggttatc
     2701 tggatgctgt acacagtggt atagttatcg aacaagagcg ggaggaatac cttgaaatcg
     2761 ctaggcgtag agcctacgac ctcaaggatt acattgatgt tctttttgac tggtttcggt
     2821 tgaactctga tgaatttacg ctgtcaatag aatctgtgga aattgcagag ttgtcacgca
     2881 atattttgaa agactggatt cctatattcc atgaaaagaa actgaatttt gaaattgata
     2941 ttccagaaaa tcgactaatg gtaaacctcg acccagatgg atattcccgt gtggtcaata
     3001 atctggttca aaatgttctt gctcacagta aggctcggca aatcaagatt accatgagtg
     3061 aggattccag aatggtatta ctccgtgttg aggatgatgg tgttgggatt gccagagaaa
     3121 atttaccaca tatttttgag cgactgtata agtgtgataa aggacgttca gaaaaaggaa
     3181 gtggtcttgg tctatctatt gtcagtcaaa tggtggagcg aatgggtggt caggtttccg
     3241 tagaaagtga gattggaaag tataccgtat ttacagtgag cttaccatta atataaaatt
     3301 gtttttcccc catgtgacat gtatacacag ggggattttt tgtaagttat aaagttgcaa
     3361 ggttaataca aggttgttgc aaggttaatg taagattgag gtggtatgat aactttaata
     3421 aacaaaggag gcttttatta tttatgaata atttaattat tgaaacaaaa aatctcacta
     3481 agcaatatgg tgctcaaaag agcgtttcta atttgaatat tcacgttcag aaaggtcgca
     3541 tttacggatt gctaggaaga aacggtgcgg gtaagacgac aactatgaaa atgttattgg
     3601 gcctaacaaa accaactact ggagaaatta aaatatttgg tcaggacatt cacaataacg
     3661 agaagaagct tcttcctcga attggatgtt tgattgaatc accagggttt tatcctaatc
     3721 tgacaggaac agaaaatctc aaaatctttg caaggcttag aggaatacca aaaaaaaatg
     3781 cagtagaatc agcactggat gtagtcggtt tgccaaacaa tgacaaaaag ttattttctc
     3841 aatactctct tggtatgaaa cagaggttgg cgattgctct tgccattatg catgacccac
     3901 aactgttgat tttggacgag cctatcaatg gacttgatcc tattggtatt gcagaagtaa
     3961 gaacgtttat tcgtgatctc tgcacagaac gaggtaaaac tattttgatt tccagtcaca
     4021 ttctttctga aattgccttg ttggcagatg acattggcat tattgaccat ggtattttgt
     4081 tggaggaaga aagtcttgcc caattagaag aaaaaaacag taaatacata cattttgctg
     4141 tatctgatgc agcacaggca gcaaggcttc tggaaaccca acttaacctg aaaaatttca
     4201 aagtagcaga taattacaat attatgctat atgatacaga tgtttctgtt gcagaaataa
     4261 atcgtgcttt cattctaaac aacattgagg tatcagaatc tcatttatgc gaagatactc
     4321 ttgaagatta cttcaagaaa gtaacagggg gtgaaggaat tgcttgatat aatttcatgt
     4381 gaattttcaa aactcaagcg gttaaaattt atactgattt ctattttagg tgcttgctta
     4441 tttccaattc ccgcaacaat tttgattgca aaggacaact tgccctttga gcaattgttc
     4501 aaattagttg tcaattttgg atatttcttg ctattaccaa ttgtattaag tattgttgct
     4561 agccaactat tttttataga aagagataat gatgtattaa aaaatcttgc aacagtgcca
     4621 gtgccaaaag gaaaactggc tctggcaaaa ttggctgtgt tgctgtttat atcattgttc
     4681 tactctgttg cagggttagg agctactatc attggaggtt tcattgttgg aatagtagag
     4741 ggggttgctg taaaattagg aatgagcatt gcttttggaa ttatgttttt tgttactgta
     4801 cttcctgttg tggtactcat tgtatatttc aatcgcagct atattttttc tattatactt
     4861 tcttttgtat atgctatttt caattttagt atatccttaa atattatcaa ttttgaacca
     4921 aataacccac tattaagcgt attacctgct cctgttataa tgcgttggtg gatggcattt
     4981 tggggagatc ccactggcga atacacggta cttagacagc catatttgct ctcaactcct
     5041 gcttgtgtag gtattttatg tttgataacc attatagcag tcctgctgat ttgtatgata
     5101 tacaaaaagc aggagaatta ggaggtatct atgcttgata taattactac agaatttcaa
     5161 aaaataaaaa gatataatat tctatggatt ggtgttgttg ctgttctgtt ttcagcacta
     5221 ttggcagttt ttcaggttgt aagttcacac ggcagtgacc ctctaacgta tgagagcttt
     5281 gcaaacggag ttatctggaa taatttcagt cttagttttc catttgggat tacacttatt
     5341 ggaggatatc ttattaaccg tgaatataca gaccaaacct taaaaaacat cctaactgtt
     5401 cctatttcat tacgcaaatt gctagtggga aaattaattg cggttggagg aattactgta
     5461 ttgttaagtc ttttcagctt cttatgcaca tttattttgg ggttgttatt ttgcaatatc
     5521 aatatatctg ttatactcgt tgtaaaatcc ttagttcaga ttttgtctgt taatctgtat
     5581 tgttatgttg ctgttttgcc gattattgct tattttggtc gtaaacaaaa tgcatttctg
     5641 acgggtgtag ggattgcatt tgtatacggt ttttgtggtg tgtttgttgc tggaagaaat
     5701 ctgacagact tttatccaat cacagcaggt cttggtctag ttggatacaa caatggtgct
     5761 ggtactgttt atcagccact tatcggtgct atgactttga ttgtaattct aatcttgaca
     5821 actattctac ttgtatttac acctaattat gataaagtta tgaccatatc taagaaaaaa
     5881 gggataaagc ataaaaagta ttctcataaa taacataaat attgtttcta ttatttaagt
     5941 tgctagacag tgaaaagaaa aaatctgtcg tacagtggct atatgctcat gtattcaaga
     6001 agctacagtt ttgatttttc ataactgtag cttctttttg tatttattaa atcacgacta
     6061 tcataatact tgcaataggt atagtaacaa gagagagtac tgtcatatgt gttttatata
     6121 ttacattaag tatattctaa aatatatgtt ttaaataata tatttgaaaa taggaatatt
     6181 taaataaaaa aaataatatt atatatagtt gacaaaaatt ggcaaatgat atactatata
     6241 aatatagaaa tagtaatcat tactattatt aaaaagggag gaattaatta tgaacttaaa
     6301 aggaactaaa acagaaaaga atttaatggc aggatttgca ggagagtcag aagcaagaaa
     6361 taaatataca tactacgctt caaaagcaag aaaagaaggt tataatcaaa tagctgctat
     6421 atttgaagaa actgctaaca atgaaaagga acatgctaaa ttatggttta aacttttaca
     6481 tgatggtatg ccttcaacag aggaaaattt aaaggatgca gcagcaggtg aaaactatga
     6541 atggactgat atgtatgcaa aatttgctaa agaagctaga gaagaaggat ttgacaagat
     6601 agcttattta tttgaagctg ttggaaaaat agagaaagag catgaagaaa gatacttaaa
     6661 gcttttagaa aacttaaatg aaggaaaaat atttaaaaga gatgaagaag ttgtttggca
     6721 atgtcaaaac tgtggtcatg tgtatgtagg tactgaagca ccagaaaaat gcccagtatg
     6781 tgaccatcca aaagcatatt ttaatataaa agctgaaaat tattaaaaat tatcattatt
     6841 aaaaaggaat gttaactatg aaattttcta aacaacgaga actgatttta aatgaaatat
     6901 taaataatcc ggttcatcct actgcggatt acctatatga aaacttaaaa aaagataatc
     6961 cgaatttaag cttaggaact gtgtatagaa atttagctca gctaacggaa catggcttta
     7021 taagaaaggt tagtattcca gggtatccag atagatttga tggtcgaata gataatcact
     7081 atcatatcat atgtgaagta tgtggagagg tatacgattt agaatccgaa gttcttaata
     7141 atttacaaga attaatatct gaggagacag acataaaaat aacatcttat aacataagtt
     7201 ttaaagggat ttgtaataat tgtaaaaggt gtagccaagt aggttagttt tcaaattcta
     7261 aaaataatta atgaggtgag tttatgtgta gtgaacaaaa attttttata tgtgagactt
     7321 gtggaaacct tgtaggaatg atacaaagtg gtggtgtacc tattttctgt tgtggaaaac
     7381 ctatgaagga acttgttcct aatacaacag atgcagcagt tgaaaaacat gtacctgtaa
     7441 ttgaagtgga tggaaataat gttactgtta aagtaagtag cacaactcat ccaatgacta
     7501 aagaacatca tatagcatgg gtgtatctta tgactgaaca aggtggtcaa cgcaaatgtc
     7561 tagcagtaga tggagaacct gtagttaaat ttgctttgaa tgatgatgat aaagtgattt
     7621 ctgcctatgc ttactgtaat ttacatggat tatggaaggc tgaactgtaa tatttaaata
     7681 aattgagtca aaaaggaggc tataaatgta ttttcataca aatagcctcc tataaattta
     7741 tataaattca agttttaatt ttgtttaatg tcaatataat ataaggagaa aataatatgt
     7801 caatttataa atgtagtgtt tgtggatata tttatgatga atctaagaat gataaaacat
     7861 gggatgaatt aagtgaagat tgggaatgcc ctgtatgtac aaaaggtcgt agttattttg
     7921 gaaagataag tactgtttac tatgaagaag atgaaaagat agcagaagac atagttgaag
     7981 atgaatctaa attaaatact gaaaaagagg gagatttaaa ttacttaagt acatatttaa
     8041 gaagagatga tgaagttgag aaacatatgg atataattca cgaaatggct gttacaggaa
     8101 aatctataat agaacctatg agaactaaac taccagtaat ttcttgggat gatattttaa
     8161 ttatgggtgc tcaattaaat ccattacctt taaatgagca tgatgaagta aatacaacaa
     8221 caataatagg aaaaaaagca aagaaaccta tgattataga aaatccagtt tatatttccc
     8281 acatgtcatt tggagctttg tctaaagaac taaaaatagc tttagcaaag ggtgcagccc
     8341 aaaataagac agctatgtgt agtggtgaag gaggtatatt accagaagag aaggaagctt
     8401 catacaagta tatttttgag tatgtaccaa ataaatatag tgtaactgaa gaaaatctta
     8461 aaaattctga tgctatagag ataaaaattg gtcaaggaac aaaacctggt atgggaggtc
     8521 atcttcctgg cgaaaaagta actgaagaaa tagcaaaagt aagaaataag cctgtaggtc
     8581 aagatgtaat aagtccatct tgttttgagg aaatacaatc caaagaggat ttaaagaaac
     8641 ttgtagatga acttagagaa gtttcagaag ggcgtccaat aggtgttaaa atttcagcag
     8701 gtcatattga aaaagatatg gaatttatag cttatgctaa acctgatttt gtaactattg
     8761 atggtcgtgg tggagctact ggagcaagtc caaagttgct taaagatgca acttcaattc
     8821 caacaatatt tgctctttat cgtgctagaa aatacataga tacacatgga ttagatatag
     8881 atttggttat aacaggtggg cttcgtatat ctactgattt tgctaaggca attgctatgg
     8941 gggctgatgc agttgctatt gcaagttctg ctcttatggc agcggcgtgt caacaatatc
     9001 gtatatgtgg ttctggtaag tgtcctgtag gagtagctac tcaggatgag gaattgagaa
     9061 aaagattaca tatagaaaat agtgctaata gagtggcaaa ctttttaaat gtaagtttag
     9121 aagaacttaa gacttttgct agaatttctg gtcataaaga tatacatgat ttaagtgttg
     9181 atgatttata tactgttaac tctgaaatat caaattatac aaacatacag catgtataga
     9241 ttgaagtttg aaactattag attttagaca gctataaaag taaatgataa atatatttta
     9301 taaaagagag tgtcttaaaa tgaacttttt agttcataag tcactctttt ttgtatgaag
     9361 ccaaatatat ttatcatttt agcaatgaaa aagaatctta tctctttatt ttgagataga
     9421 ctccttctat ttatgaaaat taaagatatt aaattgtaaa atattctgtg atgtcgtact
     9481 attaaactaa agattctgta ctttaaagta aataaaaatt taaggagtga ttattatgga
     9541 aagattgaag atacaagttt tagtcgacaa taatacttat attgatagat actttgttgg
     9601 agaaccagca gtaagctatt atattgagat tgatggaaat aggattttgt ttgactcagg
     9661 gtattcagat gtattcatat caaacgctga aaaattaaat atagatttag gaaatttaac
     9721 tcatgttgtt ttttctcatg ggcataatga ccatacaaga ggtatccagt ttttagaaaa
     9781 taggtatgat ttatctacag ttgaacttat ttcacatcct aactgtttta tacctagaaa
     9841 acatggagag aaaagcatag gagctccatt ttctgctgag gaaattaaaa atatttttat
     9901 gtataatcct aaggataagc catttaatct aagcaagaat tgtgtgtttt taggtgaaat
     9961 accttctata aatgattttg aaaaaagagc taaaattggt aaatgtaaaa taggagattt
    10021 gtgggaagat gattatgttt tagatgattc tgctatagtt tgtaaaactg ataaaggtat
    10081 ttttattgtt acaggatgtt ctcatagtgg aatttgtaat atagtagagt atgctaaaaa
    10141 ggtatgtgga gatgatagag ttattggtat actaggtggt tttcatcttt ttgaattgaa
    10201 taataggtta gatagtacaa tacaatattt ggataaagaa gaaataagaa tgttgtaccc
    10261 ttgtcactgt gtttctttta aggtaaaagc gaagatgaat gaaatattga atataaatga
    10321 agttggagta gggctgacca taagtatata gtatttgaaa gtatataaga tttaagttga
    10381 aggttaaaaa gatattttct atagaaaata tcttttttgt tacgtttatt ttaagagaaa
    10441 tcaatatact tttatatgaa atattgtaaa aaaatttatt tttaatgaga atatattttc
    10501 attaataaac aattttatta tgtattaata atgttagaat aaatataaat aaatcaaagt
    10561 tacttacatt acagtatatt ttttcacaaa atatattgat ttattctttt aaagtttgat
    10621 aattccaatg aatgtaataa aagaaggaat tttatactat actattatta ttataaaata
    10681 ataaagaaaa aattatataa taataaagaa aaaatgtata atatttaaca ttaaaaaaga
    10741 tatttcataa aattaaaaaa caaagtgaat ttgaatacta tttaaaaaat aaaataaata
    10801 tataaaaaat atttaatata aaggtagaaa taagttgaaa atgtaaagtc attggaaaaa
    10861 tatagttgaa tttaatgagc aaaaatgtta ttgttttatc aataaagtgt taaaataaaa
    10921 acttttaata tcattttagg gaggatgatt tcatgcaaaa aagtgtaa
//
LOCUS       DAJMZY010000274         8463 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.guided.140, whole genome shotgun sequence.
ACCESSION   DAJMZY010000274 DAJMZY010000000
VERSION     DAJMZY010000274.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8463)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8463)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8463
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.guided.140"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            complement(<1..109)
                     /locus_tag="OE968_003879"
     CDS             complement(<1..109)
                     /locus_tag="OE968_003879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate dehydratase"
                     /protein_id="HCP7221061.1"
                     /translation="MKRKVQVKNITIGEGRPKICVPIIGKNKKDIIKEAK"
     gene            complement(781..1596)
                     /locus_tag="OE968_003880"
     CDS             complement(781..1596)
                     /locus_tag="OE968_003880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage integrase family protein"
                     /protein_id="HCP7221062.1"
                     /translation="MVKLSDAKSWAIRMSEDGCAYKSIDNYKRSLKASFFMAIQDDCI
                     RKNPFNFQLSDVLEDTTEPKIALTPEQEMGLLSFMESDKTYCKYYDDVVILLETGLRI
                     SELCGLTLELDMKNKAIMVDHQLLSDTKIGYYVEVPKTTQGKREIPMTERAYQSFERI
                     VERRKNAKAEPIIVDGYQNFLFLKQDGLPKQATHYQSMLRALVKKYNKTHEDKLPKIT
                     PHTFRHTLCTNMANKGMSPNILQYIMGHKNITMTLGYYAHGSFSSSRAEMERL"
     gene            1688..2956
                     /locus_tag="OE968_003881"
                     /pseudo
     CDS             1688..2956
                     /locus_tag="OE968_003881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331151.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
     gene            3055..3675
                     /locus_tag="OE968_003882"
     CDS             3055..3675
                     /locus_tag="OE968_003882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HCP7221063.1"
                     /translation="MHLIDFMNEDIKKKLVKKTYKKKETILFAEQENEYVILMIDGIA
                     EAFILNVKGNISTIHLYRSGSFFGEMEQFNDGKKPVEIVAFTDCNVYKLHRDDFLNWL
                     RGDFEATKFLIREISSKLVVNAELIEELSSLSVKERLLRCISLHYYRSELNLLTKKQL
                     ASEVNAPIRSINRAINECVQEHLIAYENKRFSVINQREVLKNLPTT"
     gene            3825..4229
                     /locus_tag="OE968_003883"
                     /pseudo
     CDS             3825..4229
                     /locus_tag="OE968_003883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433844.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="oxalate:formate antiporter"
     gene            4354..5280
                     /locus_tag="OE968_003884"
     CDS             4354..5280
                     /locus_tag="OE968_003884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCP7221064.1"
                     /translation="MSDILSRITNKIGDKNIVDKLSALSKSDLNSLLLEVFDRQANTL
                     TATDILKSYQLNRFTIPSGIDPEEIHALESKLLRKAFNMDIKTIMLSPSAPLGSCSVF
                     GSVDQYNVVSALRGTETLADPSNMLAIIIADKLKRKEENNTIPIHMATTARVIRAQNF
                     VGKGLYSHFGLYCMVSSGIDTGSYTCEKMLLEKHLNYYKDILSEIENVRFSIILRKRN
                     GYKDNDGFFDRMVETIKLIFPNIELSIHNDDVDNNYYKGINFKLSVKQGNETVEIVDG
                     GFVDWTYQMLGNKKERCLISGIGLERFLVAVS"
     gene            5294..5743
                     /locus_tag="OE968_003885"
     CDS             5294..5743
                     /locus_tag="OE968_003885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCP7221065.1"
                     /translation="MELIEWNYAYITDLVEFANDKEIAKNLRDNFPHPYREQNARDFV
                     SFCLATPDVKQLSYAIFYQERAIGSISLTFEEDTSINKNAELGYWLARNYWGKGIATN
                     AVKEICKIAFEKYNLNKIHANVYSYNRGSSKVLEKCGFKIEEYCHNS"
     gene            6103..6510
                     /locus_tag="OE968_003886"
     CDS             6103..6510
                     /locus_tag="OE968_003886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HCP7221066.1"
                     /translation="MVDEKTIEHQFDSFCKTVLRNYARDIYDENKRRNDYLVSLESLS
                     LAELSKLSILDDYDSNYICMVSYDYNIRIEDVLMAQAIGKLTKRKQDIILLSFFLNMT
                     NADIATLMDLAENTIHYHKTNALKELKELMEEH"
     gene            6512..6742
                     /locus_tag="OE968_003887"
     CDS             6512..6742
                     /locus_tag="OE968_003887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCP7221067.1"
                     /translation="MKPTKEVLPFTIILLAVHGDVNAINGILKHFEHYIIRLSQKTLF
                     DEYGNPYIHVEEETKRMLGTKLITAILRFNLS"
     gene            7132..7335
                     /locus_tag="OE968_003888"
     CDS             7132..7335
                     /locus_tag="OE968_003888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HCP7221068.1"
                     /translation="MNNTDVPIWEKYTLTIEEASKYFRIGEKKLRKLADENLDSGWVI
                     MNSNRIQIKRKQFEKIVDTLDFI"
     gene            7413..7766
                     /locus_tag="OE968_003889"
     CDS             7413..7766
                     /locus_tag="OE968_003889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase DNA-binding domain-containing protein"
                     /protein_id="HCP7221069.1"
                     /translation="MSTEKRRDNKDRILRTGESQRKDGRYAYKYVYSFGKPQFVYSWK
                     LVPTDKPPKGKRDDISLRDKEKAIQNDLDDSIDTIGKKMTVCQLYAKKNGLRKNIRLN
                     TKKGRHYLMKILNKE"
     gene            7838..>8463
                     /locus_tag="OE968_003890"
     CDS             7838..>8463
                     /locus_tag="OE968_003890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CatB-related O-acetyltransferase"
                     /protein_id="HCP7221070.1"
                     /translation="MTIPSSNKVYPRSNDYQTVYLKNVITRENIEVGDYTIYNDFYND
                     PRDFEKNNVLYHYPINNDKLIIGKFCSIACNAKFLMTSGNHSMKSKSTYTFPIFYEEW
                     KLDINHITDAWDNKGNIIIGNDVWIGYDSIIMSGVNIGDGAIIGTRAVVTNDVPPYSI
                     VGGVPAKIIKKRFNNDTISKLLEIKWWDWPYKKIQSNIKHIQSGNIDK"
BASE COUNT         2981 a         1278 c         1440 g         2764 t
ORIGIN      
        1 ctttagcctc ttttataata tcttttttat ttttcccaat aattggtaca caaattttag
       61 gtctaccttc tccaatagta atatttttta cttgaacttt tcttttcata ttctcctcca
      121 taatcagaaa ttctatagga ctttaaattc tattttctgc acaatttaat tatacattaa
      181 aaatactata cattataaaa atactaattt aaaaataatt tttattctaa ttcttaaaac
      241 aatcccacat attttagaaa aggtactcta taatatacaa acacttcttt tttacctaaa
      301 tttattttaa catcctataa ttttcacaat attctttaaa ttttactcat ataaacaata
      361 ttattctgga tgctaataga attaatctat aaatcatagt ataattatgc agaaataact
      421 cgaatttcac tacttatgaa gagattgaat attaatgaat ctaaatcatt tgcattactt
      481 aagagttttg actaaagttg aacaccatac aaaagtagct actcaattgt ttatacccca
      541 accaagctta agtaatgtta tatagattct cgaaaaagaa tttggtatct ttttatttga
      601 aaaacttata ttaaatttga ttatcttttc ataagttggt aaatgtcgat atatcctgta
      661 tctacaagga gtatcggcat tttctttttg gaagatactt tgcataagtt ggcatttaac
      721 cgtataagaa tgccatcaaa agtagtaaat aagtagtaaa ctctagtcat actactagga
      781 ttataaccgt tccatttcag ctctcgaaga actaaatgaa ccatgtgcat aatagccaag
      841 cgtcatagta atgtttttat gccccataat atattgcaat atattaggac tcattccttt
      901 gttagccata tttgtacaga gtgtatgcct aaaggtatgt ggcgtaatct ttggtagctt
      961 gtcctcatgg gtcttattat acttcttgac taacgctctt aacatgcttt gataatgagt
     1021 tgcttgtttt ggtaatccat cttgtttaag aaataggaag ttctggtaac catcaacaat
     1081 gattggttct gctttagcgt tcttacgccg ttccacgata cgttcaaatg attgataagc
     1141 tctttcagtc attggaattt ctcgcttacc ctgtgtggtc tttggaactt ctacataata
     1201 gccaatctta gtatcactca acaattgatg gtctaccata atggctttat ttttcatatc
     1261 caattctaaa gtcaaaccgc ataattcaga aatgcgtagt cctgtttcta agaggataac
     1321 aacatcatca taatatttac aataagtctt atcgctctcc ataaaggata ataagcccat
     1381 ttcctgttct ggtgttagag cgatttttgg ttctgttgta tcttccaaaa catcacttaa
     1441 ctgaaaatta aatggattct ttctaataca gtcgtcttga attgccatga aaaacgacgc
     1501 tttcagtgag cgcttataat tgtcaatgga tttataagca cacccatctt cactcattcg
     1561 gatagcccag cttttagcgt ctgataattt aaccatatca atgctttttg cacctagtgg
     1621 gtcattgata gtatctatat tttgatttat aatttataca tttttttaaa aacagacttt
     1681 taactgtaaa gaatctatgt ataaacttag ctatgttgtc cgtgtatcta caaaggatct
     1741 tgacgagcta aaaaggcgtt gtgatgaagt caaagacttt tacgacgact tatcactcaa
     1801 gctcgtgcgt ccctttgggg atatgttggg attgcatggc gaatttattc ctgtcagcaa
     1861 acgttacatc aatgattata ttcaatatgt cacttcggat tttttggctg gacttggttt
     1921 tggagcgaca caaacccttg gcgaacatga ggatatctat cttggctaca atctggacac
     1981 tggaaagaat gtctatctaa aacctgccct tgctagtcaa tgggtaaagg gttctattac
     2041 caatgtgtta gcgtctgcgt ttatcggttc attgggtggt ggtaaattat tcagtaacaa
     2101 tatgcttgtt tactatgcgg tactattcgg cggacaggcg gtcatagttg accctaaagc
     2161 agaacgcggc aaatggaaag aaacgctacc agaaatagcc catgagataa acattgtcaa
     2221 tttaaccagt aatgatgaaa acaaaggatt gcttgaccct tacgtcattt tgagccgtaa
     2281 aaatgattct gaaagtttag cgattgatat cctaacattc cttgctggta tctccagtcg
     2341 tgacagtgat aagttcccag tgcttagaaa agcaatccgc aatgtaaccc aaagtgaaca
     2401 gcgagggtta ttacttgtca ttgatgaatt acgaaaagaa gatacttcta tcagtaacag
     2461 catagccgac catatcgaaa gttttgtaga ctatgatttt gcacatctac tgtttggtga
     2521 cggaaatgtg aagcagtcta tcagcttgga gaaacagctg aatattattc aagttgctga
     2581 cctcgtattg ccagatgcca acactagctt tgaagaatat acaacaatag aacttcttag
     2641 tgttgctatg ttgattgtta ttagtacctt tgcattagac tttattcata ctgaccgctc
     2701 tagcttcaag atagttgacc ttgacgaagc atggtctttt ttgcaggtgg cacaaggtaa
     2761 aacgctatct atgaaactgg ttagagcatc gcaagattca caggacaaac gaattgaacg
     2821 tttgaagaat tatctgactg aaaacctaca acagttgaat actgaaatgg ttcgctcata
     2881 tattcctact agttctattg tcaacagctt tctcagtttg agcttacttt gcagaaaaat
     2941 gacaactgga aaataataat ggaatagttt ctatgtaaat atatttttac tatcttacct
     3001 aactaattga aagatgatat aatttaatca aagatttggt aaggagggat gaatatgcat
     3061 ttaattgatt ttatgaatga agatattaaa aagaagcttg ttaaaaaaac gtataaaaag
     3121 aaagagacta ttctttttgc tgagcaagaa aatgaatatg taattcttat gattgacggt
     3181 attgcagaag cattcatctt aaatgtgaaa ggaaacatct caactattca tctttataga
     3241 agtggtagtt tttttggaga aatggaacaa tttaatgatg ggaaaaaacc cgttgaaatt
     3301 gtcgctttca cagattgtaa tgtatataaa cttcatagag atgatttttt aaactggtta
     3361 aggggagatt ttgaagctac aaaatttctg attcgagaaa tatctagtaa attagttgta
     3421 aatgctgaat taattgaaga attatcatct ttaagtgtta aagaacgact tctgaggtgt
     3481 atatccttac actattatag aagtgaatta aatctgctta ccaaaaaaca gcttgctagc
     3541 gaagtaaacg ctccaattag aagcattaat cgtgctataa atgaatgtgt acaagaacat
     3601 ctaattgctt atgaaaacaa aagatttagt gtaattaatc agcgagaggt attaaagaat
     3661 cttcctacaa cataagtata atttcaaaaa agtattgaat aataattatt caatgctttt
     3721 ttatttcggg tcaagtgacc tatttttttt tattttttca ttatataata ctcctatgca
     3781 taattatgtt ggattgatag ctaataaaag aaagtgagag gtgttatact aaaaaagaag
     3841 catacttccc aactccagac ttacagtgga ttgaagatag attttggatt tgggttcatt
     3901 acgcttgcac taagattgga cgtagagaac tatttgaaac aattgatttt ttatcttttt
     3961 taagacaatc agtacttgcc ccattaatac agcttctctt aggtaaatta cctcgtggag
     4021 ttagaaaaat tgaattggac gcaccccaat atattgaagc attagaaaag acggttgcta
     4081 accatgaata taaaagctgt gttaatgcat tgcaggctac tatcaacctg tatcttgagt
     4141 taagagagga attatcacaa agtcctattg tccgaaaggt tgaagctgaa agggttgcat
     4201 tacagtattt tcaagattta atcaaataaa cccaaagtaa aaaaatattg aatagtaaat
     4261 attcagtgtt ttttcatttt tggtcaaatg acctagatta gttgttgtaa ccattctata
     4321 attattttga aagtaacagt atggaggata actatgagtg atattttaag tagaattaca
     4381 aataaaattg gggataagaa tatagttgat aagttatcag ctctatcaaa atcagatttg
     4441 aactcacttc tattagaagt gtttgataga caagcaaata ctttaactgc aactgatatt
     4501 ctaaagtcat accaactaaa tagatttact atccctagcg gtatagatcc agaagaaatt
     4561 catgctttgg agtcaaaatt attgagaaaa gcattcaata tggatatcaa gacgattatg
     4621 ctttctccct ctgctccatt aggtagctgt agcgtttttg gctccgtaga tcaatataat
     4681 gtagtaagtg ctctacgagg gacagaaaca cttgcagacc cctcaaatat gttggcaata
     4741 attattgctg ataaattaaa aagaaaagaa gaaaataata ccatacctat ccacatggct
     4801 actactgcta gggtaataag agcacaaaat tttgtaggta aaggtttata ttcacatttt
     4861 ggcttatatt gtatggtttc atctggtata gatacagggt cttacacttg tgaaaaaatg
     4921 ttgttagaaa agcacttaaa ctattataaa gatatattaa gtgaaataga aaatgttcgt
     4981 ttctctatta ttctacgcaa aagaaacgga tacaaagata atgacggatt tttcgacaga
     5041 atggttgaaa ctatcaaact tatttttcct aatatagagt tatcaattca taatgatgat
     5101 gttgataata attattataa aggtatcaat ttcaaattat cggtcaaaca aggaaatgaa
     5161 accgttgaaa tagttgacgg tggatttgtt gactggactt atcaaatgct tggaaataaa
     5221 aaagaacgct gtttgataag tggtattggc ttagaaagat ttcttgtagc tgtttcataa
     5281 aaggagaaga aaaatggaac ttatagagtg gaattatgct tatattaccg atttagttga
     5341 gtttgcgaat gataaagaaa ttgcaaagaa tcttcgtgac aacttccccc acccttatag
     5401 ggagcaaaac gctagagatt ttgttagttt ttgtttggca actccagatg ttaaacaact
     5461 tagctatgct attttttatc aagaaagggc tattggaagt atcagcctaa catttgaaga
     5521 agatacctct attaataaaa atgctgaatt aggttactgg cttgctagga actattgggg
     5581 caaagggata gcaacaaatg cagtaaaaga aatatgcaaa attgcctttg aaaaatacaa
     5641 ccttaacaaa attcatgcta atgtatattc ctacaataga gggtcaagta aagtattgga
     5701 aaaatgtggt tttaagattg aagaatactg tcacaattca taataaagaa tagaaacatg
     5761 attgattgcc atgtatatag tttaattcga ccgcaatagc atttattaga attaacctac
     5821 tttttaataa cagaataagt ttttcccctc tattaatttc ttatgcatct ttgtattttt
     5881 atgaaaagct agccaatgca tatttccata catcaatatg gtggtggctt acaaccaata
     5941 taaattaaat acgttttaaa gaatacacat ttttgcccta taggcagagt gtgtattttt
     6001 ttctcttttt tttgaaattt atcgaagatt taacgccctc ccaccgtgat aggagtaagc
     6061 aaggttattt aactccttgc gatggaaaga gggtgaaatc ttatggttga tgaaaagaca
     6121 attgaacatc aattcgacag tttctgtaaa acagttttgc gtaactatgc tagagatatt
     6181 tatgacgaaa ataaacgcag aaatgattat ttggtatctc tcgaatcttt gtcacttgca
     6241 gaattaagta aattgagtat tttagatgat tatgattcta actacatctg tatggtttct
     6301 tacgactaca acatacgaat tgaagatgta ttaatggcac aagcaatcgg aaaacttaca
     6361 aaaagaaaac aagatataat tctactttca ttctttctca acatgacaaa tgctgacata
     6421 gcaacattga tggatttagc agaaaatacc atacattatc acaaaacaaa tgcactaaaa
     6481 gagttgaaag aactcatgga ggaacattga aatgaaacct actaaagaag tattaccttt
     6541 tacaattatt ttacttgctg tacatggcga tgtaaatgca ataaacggaa tacttaaaca
     6601 ttttgaacac tatatcattc gtctttcaca gaaaacttta tttgatgaat acggaaatcc
     6661 ctatattcat gtagaagaag aaacaaagcg aatgctagga acaaaactaa tcactgctat
     6721 tttgagattt aatttgtctt aatctcgccc tctctccatg tatcaagcta tttggtacat
     6781 ggagaatcac taattatttg tctataaaag cccataagct attgtgattt tttatagaca
     6841 aatcaatgcc gactgttctt tgacaactga ataaagtaga tagatacgtt tgtgatacag
     6901 atagccaaca aatactatac gccatgacct taatcaagag agctactata tagtgatttg
     6961 tgaataacct ttggaacggt tgttttgccg taacctgtac cacagtataa tgatacacct
     7021 gtatgacacg gttctgccca taagaatggg attggttaaa ataccaatgg agcttaccaa
     7081 agccatctat ctacttctga actacgaaca tagaaaggag tgatacattc tatgaacaat
     7141 actgatgtac ctatttggga aaaatatacc ttgacgattg aagaagcgtc aaaatacttt
     7201 cgtattggag agaaaaaatt acgtaaactt gctgatgaaa accttgattc tggctgggtc
     7261 attatgaata gcaatcgcat tcaaataaag agaaaacaat ttgagaaaat cgttgataca
     7321 cttgacttta tctaatgaaa ttgagcctta tatgttataa tattcatatg acgtatcaag
     7381 ctcaattcgg ttattgagag gagcttctta tcatgtcaac tgaaaaaaga cgagataata
     7441 aagatagaat tttaagaact ggagagagcc agagaaaaga tggaagatac gcatataagt
     7501 atgtatattc atttggtaaa ccacaatttg tttactcttg gaaacttgta cctactgata
     7561 aacccccaaa gggaaaacgt gatgatatat cattaaggga taaggaaaaa gcaatacaaa
     7621 atgaccttga tgatagcatt gacactattg gtaagaaaat gacagtttgt cagttatacg
     7681 ctaaaaagaa tggactaaga aagaatatcc gacttaacac taaaaaagga cgccattatc
     7741 ttatgaagat tcttaacaag gagtgattct gtgaagagat gtattgtagt agtggaatag
     7801 tcaaaaacat aatatatatt aaaggagaga tttaaatatg actattccaa gttcaaataa
     7861 ggtatatcca agaagtaatg attatcaaac tgtatatctt aaaaatgtaa taacaaggga
     7921 aaatatagaa gttggagatt acacaatata taatgacttt tataatgacc caagagattt
     7981 tgagaaaaac aatgtattgt atcattaccc tataaacaat gataaattaa taattggtaa
     8041 gttttgctca atagcatgta atgcaaaatt tctaatgact agtggaaatc actcaatgaa
     8101 atcaaaatcc acatatactt ttcccatctt ttatgaagaa tggaaactcg atatcaacca
     8161 tataacggac gcttgggaca ataagggtaa cattataatt ggaaatgatg tgtggatagg
     8221 ttatgattct ataattatgt caggtgtaaa tattggtgat ggtgcaatta ttggaacaag
     8281 agcagtagtt actaatgacg ttccaccgta ttctattgtt ggaggagtac ctgcaaaaat
     8341 tataaaaaag agatttaata atgatacaat ttcaaaatta ttagaaatta aatggtggga
     8401 ttggccatat aaaaaaattc aatcaaacat taagcatatt caatcaggaa atattgataa
     8461 att
//
LOCUS       DAJMZY010000275         7296 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.guided.150, whole genome shotgun sequence.
ACCESSION   DAJMZY010000275 DAJMZY010000000
VERSION     DAJMZY010000275.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7296)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7296)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7296
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.guided.150"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            278..1231
                     /gene="blaCDD"
                     /locus_tag="OE968_003891"
     CDS             278..1231
                     /gene="blaCDD"
                     /locus_tag="OE968_003891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDD family class D beta-lactamase"
                     /protein_id="HCP7221071.1"
                     /translation="MKRKKNFIWIAILLVGVVMVMYYVGKKHNDINQKTDKNYIKSEL
                     NKSELNKSKIENNDKNKKEKINMVDYSDCFEGISGGAIFYNTKNKEYNIYNKELIETR
                     RSPCSTFKIVSTLIGLEKGVINSKESVMGYDGTEYPNKNWNKNLSLEEAFKESCVWYY
                     KKLIDKVDAKSVQNILDDLKYGNCDISEWEGDLKNGKGHLNGFWLESSLQISPKEQVQ
                     TMAKIFEGDTNFKKEHINILRDIMKIDINDKNINVYGKTGTGFDEKNKRVDAWFVGML
                     EREGDTYYFAIKSDDSNKEITGPKVKEIAINIIKKYYSVRE"
     gene            1575..2258
                     /locus_tag="OE968_003892"
     CDS             1575..2258
                     /locus_tag="OE968_003892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCP7221072.1"
                     /translation="MEILKCENLTKIYGSNQTRVTALNNVNLSVQKGDFVSIVGASGS
                     GKSTLLHLLGGVDRPTSGKIYVEDTEISSLKEEALAVFRRRKVGLIYQFYNLIPTLDV
                     RKNILLPMLLDKRKVDEDRFSEIVSILGLSDRLNHLPSQLSGGQQQRVSIARSLIYRP
                     AILLADEPTGNLDRKNSEEIVDLLNLSNKRFNQTILLITHDEKIALEANRIVTMEDGV
                     IVSEKVVKK"
     gene            2255..4915
                     /locus_tag="OE968_003893"
     CDS             2255..4915
                     /locus_tag="OE968_003893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCP7221073.1"
                     /translation="MNILQEYTLDFVRRNKRSSIAIMLAILLTTTMMSSLCGLLYTMW
                     TDFIRLSIEKEGNWHGELFDYTYGSDLPLIENFSSVDDVMVKGQWYVGKINDEKRDYI
                     IYRNATSEYWNSMPEKDTIIEGRRPNNANEIALSKQYFENNPSVKIGDKITLPIGYRI
                     LNGKPLEPIAPKSKGESFKKISEATLTIVGKVDVSTSSVIPAYTALGYLDKTSIKPND
                     SITVYLRFKNIRDTYKELPKLAKSLGWKTNEYGKYNLKYNSNYLLKMLVFSPEQKASM
                     SSISKFSTPIMYLTIAIFTVAVFVMVIYNAFSLSANARLTQLGILSSVGASPKQIKRS
                     VVFEGFLLTIIPLPIGLFLGWLLCNRLIVYVNSVNYHTDVPEVVFTYGIPAFLPAVLL
                     TIVTVWISALIPARKVSKISPIEAIRQGDSVKIKKSHKYSLGKIFGIEGELASNALRA
                     RKKSYRTATISLTLSFLLLTCFLHIIANQEGAKAVYGSDNYKDQRDIAVYLENSEPIE
                     SAFIEKLDNTEGVKSSLYYQKMSASTWLTEKDASKELAKNGGFKSIVSSKKYSPIERD
                     GKFRIISNIIGLDDKSFTEYCRQISVDPKLFYNTKNPTSIVYNKEEDINRSTRRNKVY
                     IDYLNLSIGDNIKLNEKVYDEDKGDYTYNMKVGAITSTLPKIVDTSSKYTLMQIVPMS
                     MVQEISKNYDEVSRLRSNRLIGVFKVNNREDIPRVREKLESIYNKDYGSGDYSIEDVL
                     ESEKQKASGIKTMNLIVGFITGLLAMIGLSNVLATVSGNIRSRRQEFAMLRSVGLSPE
                     GIKKMLILEGLFLGITPLLLSIPVQIGIVYAFLRINEIYFIEYLPFAPISTIIGFTIL
                     ILFIVIASYMTGYKQLKNENIVESIKNETI"
     gene            complement(5096..6277)
                     /locus_tag="OE968_003894"
     CDS             complement(5096..6277)
                     /locus_tag="OE968_003894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HCP7221074.1"
                     /translation="MKTPRNINSTVVFIIFCLIVTFLLSVILTTITSFNEYNVLSKAL
                     GASYEYNPKSTESILKSLKNSSDKDFKTGNEILSKHGYSKSTFWSKNFFYFLVISFGI
                     ISTMATVIYIIKHRTNKQKLSRINNLTQYLEEVNLGKESVLLRCEDEFSHLEDEIYKT
                     VGELRCSKEFALKERQTLSDNLADIAHQLKTPITSMSLMAQLLSENCPDEEIDYINRL
                     TNQISRLERLVSSLLTLSKLDASTLIFESKLIDVHSLLTYAIEPIEGSLREKHQTFTI
                     EASPSVEFEIDINWTLEALLNILKNCSEHIEDGGYIVAYYSQNPLYVEIIIEDNGKGF
                     AQEELPYIFNRFYRGKNASKDSIGIGLALSKSIIERQNGTLHAENCHNGGARFIIKFY
                     T"
     gene            complement(6277..6939)
                     /locus_tag="OE968_003895"
     CDS             complement(6277..6939)
                     /locus_tag="OE968_003895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCP7221075.1"
                     /translation="MAKILLLEDDDTITFGIKTSLEKKNHTVCCYNTIAEAKKNFDKT
                     IDLILLDLNLPDGIGYEFCQYVKSIEDTPVIFLTVRDDEKDIIRGLDMGADDYVVKPF
                     LLSVLQSRINAVLRRTHSNTNNTITCENISLNKVEVKAYLDNVEVPLTAGEYKLLLSL
                     MENKNRAMTRTKLLEMLWDVDGNFVNDNTLTVTIKRLREKLKNPPCIKTLRGIGYRME
                     DS"
     gene            complement(7071..>7296)
                     /locus_tag="OE968_003896"
     CDS             complement(7071..>7296)
                     /locus_tag="OE968_003896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCP7221076.1"
                     /translation="MFDEIQGMFEIGKNDRSIRHDIEIPTLMYSSIFTLTGFFNLLSV
                     TGKSYLNNFNIDEEKFIETTLALLIDSIKA"
BASE COUNT         2718 a          919 c         1157 g         2502 t
ORIGIN      
        1 attgtaatat ttaaatatta caatagtaag ttttaaatgt ggaatcaatt attatatcac
       61 aaattaaaag gaggacagga tgttattaat agttacctaa ttatcttcgc aataggttta
      121 atcaacataa ttgtactagg tgaagaaaat ataagagata cagctattca tttagtcttg
      181 tttcttataa gtagaaccta gattggagta tattacaaat aatgtctact attttaatag
      241 taggttataa atttaaatat gggagatgat ataaattatg aaaagaaaaa agaattttat
      301 ttggatagct atcttattgg ttggtgtagt tatggtaatg tattatgtag ggaaaaaaca
      361 taacgatata aatcaaaaaa ctgataagaa ttatataaaa tctgaattaa ataagtctga
      421 attaaataaa tccaaaattg aaaacaatga taaaaacaaa aaagaaaaaa ttaatatggt
      481 tgactatagt gattgttttg aaggtattag tggaggagct attttttata atactaaaaa
      541 taaagaatat aatatatata acaaagaatt aattgaaaca agaaggtcac catgttctac
      601 ttttaaaata gtttcaactt taattggttt agaaaaaggg gtaataaact caaaagaatc
      661 agttatggga tatgatggta cagagtatcc aaataaaaat tggaataaaa atcttagttt
      721 agaagaggca tttaaggagt cttgtgtttg gtattacaaa aaattgatag ataaagttga
      781 tgctaaatct gtccaaaaca ttttagatga tttaaagtat gggaattgcg atattagcga
      841 atgggaaggc gatttaaaaa atggaaaggg acatttaaat ggattttggt tagaatcttc
      901 attacaaata tctccaaaag aacaagtgca aacaatggca aaaatatttg agggagatac
      961 aaactttaaa aaagagcata ttaatatttt aagagatatt atgaaaatag atataaatga
     1021 taaaaacata aatgtatatg gaaaaactgg aacaggattt gatgaaaaaa ataaacgtgt
     1081 ggatgcatgg tttgttggta tgctagagcg tgaaggtgac acctattatt ttgctattaa
     1141 atcagatgat tccaataaag aaattacagg gccaaaggta aaggaaattg caattaatat
     1201 aattaagaaa tattatagtg taagggaata aacttaattt tatttgtaaa tattatttac
     1261 ctatagtctg taatatttat taaataattt tactaaattg agtctatata gagcaaaact
     1321 cctttagtac ataaaatact tgctattgat tattaaattg aatacctata gatttaaagt
     1381 taataccttt taaagactat gtaatatatt aaaagtataa ataaaatata ttgcatagtt
     1441 tttgttttat attataattt taaataatgt gcaaaaacta aacaatattt ttaatagtaa
     1501 tttatatttg tattcatgtc actataatgt cattttaggt tgctaaaatt taaccataaa
     1561 ggagatgatt gtatatggaa atattaaaat gtgaaaatct cacaaaaata tatggttcaa
     1621 atcaaaccag agtgacagcc cttaataatg taaatttatc agttcaaaaa ggtgattttg
     1681 tatccattgt aggagcatct ggttctggca aatctacatt gttacatctg cttgggggag
     1741 tagatagacc tacatctgga aagatttatg ttgaagatac agaaatatca agtttaaagg
     1801 aagaagctct tgcagttttt agacgtagaa aagtaggtct tatttatcaa ttttataatc
     1861 ttatacctac ccttgatgtt agaaaaaata tattattacc catgttactt gataaaagaa
     1921 aggtggatga ggatagattc tctgagattg tatctatatt gggattatct gatagattaa
     1981 accatcttcc aagtcaactt tcaggtggac aacaacaaag ggtatctata gctagaagtt
     2041 taatctatag accagctatt ttattagcag atgagccaac tggtaatctt gatagaaaaa
     2101 attcagaaga aattgtagac ttgttaaact tatcaaataa acgatttaat cagacaatac
     2161 ttcttattac tcatgatgag aaaatagcac tagaggcaaa tcgtattgta actatggaag
     2221 atggagtgat tgtctctgaa aaggtggtga agaaatgaat attcttcaag aatacacctt
     2281 agactttgta cgacgcaata aacgtagtag tatagctata atgttagcta tattacttac
     2341 tacaaccatg atgtcttctt tgtgtggact gttgtatacc atgtggacag attttataag
     2401 actttcaatt gagaaagaag gtaactggca tggtgaattg tttgactata cttatggaag
     2461 tgacttacca ttaattgaaa atttttcttc agttgatgat gtaatggtaa aaggacaatg
     2521 gtatgtaggc aaaattaatg atgagaaaag agattatata atttatagaa atgctacatc
     2581 agagtattgg aattctatgc cagaaaagga tactataata gagggtcgtc gaccaaataa
     2641 tgctaatgaa attgcattat caaaacaata ttttgagaat aatccaagtg taaaaattgg
     2701 tgataaaatt actctcccaa taggatatag aatcttaaat ggaaagcctc ttgaacccat
     2761 agccccaaaa tcgaaagggg aaagttttaa aaaaatttca gaggctacat tgacaatagt
     2821 aggaaaggta gatgtttcta cttcatcagt aatacctgca tatacagctc ttggatatct
     2881 tgataaaaca agtataaaac ctaatgatag tataactgtg tacttgcgat ttaaaaatat
     2941 aagagacacg tataaggaac ttccaaaact tgctaaatca ttgggatgga agactaatga
     3001 atatggaaaa tacaatctta aatacaatag taattatctt ttaaagatgt tagtcttttc
     3061 accagaacag aaagcatcta tgagtagtat atcaaaattt tcaactccta ttatgtatct
     3121 tacaatagca atttttacag tagccgtgtt tgtaatggtg atttacaacg cgttttcact
     3181 gtctgcaaat gctagactta ctcagttagg gatattatct agtgttggtg catcaccaaa
     3241 acaaattaaa aggtctgtag tgtttgaagg ctttttactg acaattatac cattaccaat
     3301 aggtttattt ttaggatggt tattgtgtaa taggcttata gtttatgtta attcagttaa
     3361 ttatcatact gatgttccag aagtggtatt tacttatggt attcctgctt ttctgccagc
     3421 agttttactt acaatagtaa cagtctggat ttctgcactt ataccagcac gaaaagtatc
     3481 aaagatatct cctatagaag caatacgaca aggagatagt gttaaaatca aaaagtcgca
     3541 taaatattca ttaggaaaga tatttggaat agaaggagaa cttgcatcaa acgcactacg
     3601 tgctcgtaaa aaatcttatc gtactgcaac aatatcttta acattatctt ttttattact
     3661 tacatgtttt ttgcatataa ttgcaaatca agaaggagca aaagctgttt atggaagtga
     3721 taattataag gaccaaagag atatagcagt ttatttggaa aatagtgaac ctatagagtc
     3781 tgctttcatt gaaaaattag ataatacaga aggtgtaaaa agttcactat attatcaaaa
     3841 aatgtctgct tccacttggc tgactgaaaa agatgcatca aaagaacttg cgaaaaatgg
     3901 aggatttaaa agtatagttt catctaaaaa atactctcct atagaacgtg atggcaagtt
     3961 tcgtataatt tcaaatataa ttgggcttga tgataagagt tttacagaat attgtaggca
     4021 aatttctgta gacccaaagt tattttataa tacaaaaaat ccaacctcaa ttgtatataa
     4081 taaggaggaa gatattaatc gtagtacacg tagaaataaa gtatatatag attatttaaa
     4141 tctttcaata ggagataaca ttaaattaaa tgaaaaagta tatgacgaag ataaagggga
     4201 ttatacttac aacatgaaag tgggagctat tacaagcaca cttcctaaaa tagtagatac
     4261 tagttcaaag tatacattaa tgcaaatagt tccaatgtct atggtacagg aaatatctaa
     4321 aaattatgat gaagtaagta ggttacgttc aaataggctg ataggagtat ttaaagtaaa
     4381 taatcgtgag gacattccta gagtaagaga aaaattagag tccatttata ataaagacta
     4441 tggttcagga gattatagta ttgaggatgt tttagaaagt gaaaaacaaa aggctagtgg
     4501 aataaagacc atgaatttaa tagtaggctt tattacaggt ttattggcta tgattggatt
     4561 atcaaatgta cttgctacag tgtcaggaaa tattagaagt agacgacaag agtttgctat
     4621 gttgcgttct gttggattat ctccagaagg cataaaaaag atgcttattt tggaaggttt
     4681 attcttagga attacaccat tactacttag tattcctgtg caaataggaa tagtgtatgc
     4741 ttttctacgt ataaatgaaa tatattttat agagtattta ccatttgcac ctatatctac
     4801 aataataggt tttactatat tgatactttt tattgtaata gcatcatata tgacaggata
     4861 caagcagttg aagaatgaaa atatagtaga atctataaaa aatgaaacaa tataaacaaa
     4921 atctatttga acttatttaa aggtttcgat ttaagactac ttacaagtat agggatagtt
     4981 aagttgtttg tttaataaaa ccttaaatgt aaatagaagt atattactaa aacaatagat
     5041 aacatagaat atagatatag ctggattata ggtattttac ctataatcca gcattttatg
     5101 tgtaaaattt aattatgaat cttgcaccac cattatggca attttctgca tgtagagtac
     5161 cattttgacg ttctataata gactttgata gagcaagccc tataccaata ctgtccttac
     5221 tagcattttt accacgataa aatctattaa aaatatatgg aagttcttcc tgagcaaacc
     5281 ccttaccatt atcttctatg ataatctcaa catatagagg attttgacta taataagcaa
     5341 ctatatatcc accatcttct atatgctcac tacaattttt aagaatattt aaaagagctt
     5401 ctaaagtcca attaatatcg atttcaaatt ctaccgaagg agaagcctcg atagtaaatg
     5461 tctgatgttt ttctcttaaa gaaccttcta taggctcaat tgcataagta agaagagaat
     5521 gtacatctat aagtttgctt tcaaatatta aagtacttgc atccaatttt gataatgtaa
     5581 gtaaagatga aactagtctc tcaagtcttg agatttgatt tgtaagtctg ttaatataat
     5641 ctatttcttc atctggacaa ttttctgaaa gtaattgtgc cataagtgac atagaagtaa
     5701 ttggagtctt aagttgatga gcaatatctg caagattatc tgaaagagtt tgtctttctt
     5761 ttaaagcaaa ttcttttgaa caacgaagtt ccccaactgt tttatatatc tcatcttcaa
     5821 ggtgagaaaa ttcatcttca catcgtaaaa gtacagactc ttttcctaaa ttcacttctt
     5881 ctaagtattg agtaagattg tttattctac tcagtttttg cttatttgtt ctatgtttga
     5941 ttatatatat aactgtagcc attgttgaaa ttataccaaa cgatatcact agaaaataaa
     6001 aaaagttttt actccaaaat gtacttttag aatatccatg ttttgataaa atttcatttc
     6061 ctgttttaaa atccttatca ctagaatttt tcagtgattt tagtatactt tctgtagact
     6121 taggattgta ctcatatgat gcaccaagag ccttagacag tacattgtat tcattaaaag
     6181 aagttatagt tgttagaatt acactcaata aaaaagttac aattaagcag aatattataa
     6241 aaacaactgt actgttgata tttcttggag ttttcactag ctgtcctcca ttctatatcc
     6301 tatgcctctt aacgttttta tacaaggtgg attttttaat ttttctctaa gacgttttat
     6361 tgtaacagta agagtgttat catttacgaa attaccatct acatcccaga gcatttctag
     6421 taactttgta cgagtcatag ctctattttt attttccata agacttagaa gaagtttata
     6481 ttctcctgct gtcaaaggta cttcaacatt atctaaatat gctttgactt caaccttatt
     6541 caagcttata ttttcacatg taatagtatt gttagtattt gaatgagttc ttctaagaac
     6601 tgcattaatt ctggactgaa gtactgagag caaaaacggt ttaaccacat agtcatctgc
     6661 acccatatct aatccacgta taatgtcttt ttcatcatca cggactgtca aaaatatcac
     6721 tggagtatct tctatacttt taacatattg gcaaaactcg tatccaatac catcaggtag
     6781 atttaaatca agcagaatta aatcaatagt tttatcaaaa ttttttttag cttcagcaat
     6841 cgtattataa caacatacag tgtgattttt cttttcaagg gaagttttta ttccaaatgt
     6901 aattgtatca tcatcttcta aaagaagtat tttagccatt tacttttaat cctttcagta
     6961 atttagttat tccattaact aagttattag ttttatgttt aatatttttt atattagaga
     7021 tagaaaaaat tatcatttaa gtatataaac tttaatttat aaacttaggt ttatgcttta
     7081 attgaatcta ttaaaagagc aagagttgtt tcaataaatt tttcctcatc tatattaaag
     7141 ttgttcaggt atgattttcc tgttacagat agtaaattaa aaaatcctgt aagtgtaaat
     7201 attgatgaat acataagagt aggtatttca atatcatgcc taatacttct atcatttttt
     7261 ccaatttcaa acattccttg tatttcatca aacata
//
LOCUS       DAJMZY010000276         6288 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.guided.161, whole genome shotgun sequence.
ACCESSION   DAJMZY010000276 DAJMZY010000000
VERSION     DAJMZY010000276.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6288)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6288)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6288
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.guided.161"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            9..710
                     /locus_tag="OE968_003897"
     CDS             9..710
                     /locus_tag="OE968_003897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanG-Cd-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HCP7221077.1"
                     /translation="MNENILIVDDEKEIADLIEVYLKNEGFTVYKFYTGKEALECIES
                     KNLDMAILDIMLPDIDGFHICQKIREKYYYPIIMLTAKIEDIDKIMGLTIGADDYITK
                     PFNPLEVVARVKTQLRRYMRYNNSYEQQSIIVNEYDIKGLIINKETHKCSLFGKEVAL
                     TPIEFSILWYLCEHQGKVVPSEELFEAVWGEKYLDNNNTVMAHIGRLREKIHEPSKNP
                     KFIKTVWGVGYTIEK"
     gene            760..1842
                     /locus_tag="OE968_003898"
     CDS             760..1842
                     /locus_tag="OE968_003898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HCP7221078.1"
                     /translation="MRTALMAFIAIIFIWILYSFILYGKFSIWIVSFFENAFRMEYKA
                     ALNLYQQIFRNSMELFMILAMVIVFFIIFRVYLNWFTKYFSEINQGIDSLIKEDVGEV
                     ALSPELLAIEKKINSIKHILEQRKFETQMAEQRKNELIVYLAHDLKTPLTSVIGYLTL
                     LRDESQISEELRKKYLSISLDKAERLEDLINEFFEITRFNLSNISLEYSTVSLTRMLE
                     QLTYEFKPTLMSKNLKYTLNVTPNMMIRCDVNKMQRVFDNLLRNAVYYSFEDTTIEIT
                     AVQEDDYIKLKFINHSNTIPEEKLERIFEQFYRLDTSRNSNSGRAGLGLAIAKEIVEL
                     HNGTITAHSENNIITFKVIIPIVGNL"
     gene            2103..3203
                     /gene="vanG"
                     /locus_tag="OE968_003899"
     CDS             2103..3203
                     /gene="vanG"
                     /locus_tag="OE968_003899"
                     /EC_number="6.3.2.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-serine ligase VanG"
                     /protein_id="HCP7221079.1"
                     /translation="MNNKKIAVIFGGNSTEYDVSLQSAFAVLENLNTEKYDIIPIGIT
                     REGNWYHYIGDYNNIQNNTWFERDTDIIPVIVSQNRVKNGIIEFLIPDAVSQNHIPNS
                     AIESCENDIKYTKLDFVFPVLHGKNGEDGTVQGLFELAGIQVIGCGTLSSALCMDKDK
                     SHKLVHSEGIKVPKSILLKYSDKFNVAELSKDLTYPLFIKPVRAGSSFGISKIYKKEE
                     LQVAVDLAFEHDNEVIIEENIDGFEVGCAVLGNNDLLVGRVDEIELSKGFFDYTEKYT
                     LKSSKIHMPARIDLDCEKRIQETAKIIYRTLGCSGFARVDMFLTPSGEIIFNEVNTIP
                     GFTSHSRYPNMMKGIGLSFEEILDKIIEVYIK"
     gene            3200..4006
                     /locus_tag="OE968_003900"
     CDS             3200..4006
                     /locus_tag="OE968_003900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HCP7221080.1"
                     /translation="MMNNILLDKNKEDKMTNTILLTKDKVYDGNLILVNAFLPVKTSE
                     DIDLIPVDTRFPSILMKREATNILQNILKSICGINEIVPVSGYRTAEEQQDIYSSSLR
                     DNGKDFTKKFVALPNHSEHQTGLAIDLGLKKEVIDFICPEFPYNGICNEFRKAALHYG
                     FIERYQCKKEEITGISQEPWHFRYVGYPHSEIINKMNLALEEYIEYIKRFSYTNCLKI
                     EDKEKIIEIFYVPIHTKEEVRISIPEQCVYQISGNNKDGFIVTFWRNRKD"
     gene            4024..6162
                     /gene="vanT"
                     /locus_tag="OE968_003901"
     CDS             4024..6162
                     /gene="vanT"
                     /locus_tag="OE968_003901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine racemase VanT catalytic subunit"
                     /protein_id="HCP7221081.1"
                     /translation="MIRNKSYAGLDYFRIIAALLIIAIHTSPLLSYSKMADFVLTSII
                     ARIAVPFFFMLSGFFLISTYNYNCNKLKSFLKNVLFIYGIAIVIYIPLNIYTGYFSMN
                     NLVPNIIKDIVFDGTLYHLWYLPASIIGASIAYFLVKKLGLKYSLVITIVIYVIGMFG
                     DSYYGFLEKIPLLKNLYGYIFEVSDYTRNGIFFAPVFFILGGIISNKSNYMSTKNSLI
                     GFLISFLLMLCEGMFLHKLGVQRHDSMYIMLLPCMYFLFTALTFLKGSRARLLRTSSL
                     IIYIIHPMMIVVIRMFSKIFGIQTVLVDNSLIHYIVVSIASFIASIIIILILKPLKKD
                     LKGEHKVNTNRAWIEIDLNNLEHNVKMIQKAMPEDCELMAVVKANAYGHSAFEVATCA
                     NQIGVKAFAVATIDEGIDLRRYGILGEILILGYTNPIRAKELHKYNLTQSVIDLNHAI
                     SLNKQKYNIKSHIKIDTGMHRLGFDVNDVRSILKAFKLKYLDICGIFTHLCVSDSLKD
                     EDVDFTNKQIECFYKLIDFLLKKGIKIPKVHIQSSYGFFNYPNLKCNYVRIGIALYGI
                     LSFPNDTTKLQLDLRPVLSLKSQVILIRKIQKDDSFGYGRVFIASRDSVIAILSIGYA
                     DGIPRNLSCGKSYVIINGCRAAIVGRICMDQLAVDITDIPNVEVGNTAIIIGRDNLSE
                     LSVSEVANNSCSISNELLSRVGRRLNVIKK"
BASE COUNT         2312 a          710 c         1099 g         2167 t
ORIGIN      
        1 aataatctat gaacgaaaat attttgattg tggatgatga aaaagaaata gcagatttaa
       61 ttgaagtata tttaaaaaat gaaggtttta cagtatacaa gttttataca ggtaaggaag
      121 ctctagaatg tattgaatct aaaaatttgg atatggctat tttagatatt atgcttcctg
      181 atattgatgg atttcatatt tgccagaaaa ttcgagaaaa atactattat cctatcatta
      241 tgttaacagc taaaattgaa gatatagaca agataatggg tttaaccata ggtgctgatg
      301 attatataac aaagccattt aaccctttgg aagttgttgc aagagtaaag acacaattaa
      361 gaagatatat gcgatataat aattcttatg aacaacagtc gataattgtt aatgagtatg
      421 atattaaagg attgattatc aataaagaaa cacataaatg tagtttattt gggaaagaag
      481 tagcattaac accgattgaa ttttctattc tttggtattt atgtgaacat caaggaaaag
      541 tggttccttc tgaagaattg tttgaagctg tatggggaga aaaatatctt gataataata
      601 acacagttat ggctcatata gggcgattac gtgaaaaaat tcatgaacct tctaaaaacc
      661 cgaaatttat aaaaactgta tggggagtag gttatacaat tgaaaagtaa aaatattaaa
      721 gtcaatcctg actttactca agtgagaaat aaaattttta tgagaacagc tttaatggca
      781 tttatagcca ttattttcat atggatttta tattctttta tattgtatgg taagttttct
      841 atctggatag tatcattctt tgaaaatgct tttcgtatgg aatataaagc tgcattgaat
      901 ttatatcagc agattttccg taatagtatg gagctcttca tgatactagc tatggtgatt
      961 gtgtttttta taatattccg tgtttattta aattggttta caaaatattt tagtgaaata
     1021 aatcaaggta ttgactctct tatcaaagaa gatgttggag aagtggcttt atctccagag
     1081 ttattggcaa tagaaaagaa aataaactca attaaacata tacttgaaca acgtaaattt
     1141 gagacacaaa tggcagaaca acgtaagaat gaacttattg tttatcttgc acatgattta
     1201 aaaacaccac ttacatcagt tatagggtat ctgacactac ttcgagatga aagtcagatt
     1261 tctgaagaac tgcgaaaaaa atatttatct atttcgttgg ataaggcaga gcgtcttgaa
     1321 gatttaatta atgaattctt tgaaattaca aggtttaatt tatcaaatat atcacttgaa
     1381 tacagtacag taagcttaac tcgtatgctt gaacaactaa catatgagtt taaacctact
     1441 ttgatgagta agaatttaaa atatacactg aatgttacac caaatatgat gataaggtgt
     1501 gatgttaata aaatgcaacg tgtatttgat aacttattac gaaatgctgt ttattatagt
     1561 tttgaagata ctactattga aataacagct gtacaggagg atgattatat aaagcttaaa
     1621 tttataaatc atagcaatac gattccagag gaaaaacttg agcgtatttt tgaacaattt
     1681 tacaggttgg atacatctcg taattcaaac agtggtagag ctgggttggg acttgctata
     1741 gctaaagaaa tagtggagct tcataacggg acaataacag ctcatagcga gaacaatata
     1801 attaccttta aggttattat tccgattgta ggaaatttgt aagaatttaa gtataaaaaa
     1861 ataggaaatt ctttaggata aataaataaa gagcactctt gttattgata taattactgt
     1921 atcaaaacaa gagtgctttt attttgatac agtaattata tcaatagaaa aatgtgaaaa
     1981 tatattatgt ggaacagatg caattgtaag tgaaggttga ttggatttga aatagaaaaa
     2041 gtattttaac atgtttctgt agattgtata aaaataaata aatcaacaaa ggagaatcaa
     2101 agatgaataa taaaaaaatt gcagttatat ttggtggaaa ctcaacagaa tatgatgtat
     2161 cattacaatc agcttttgca gtacttgaga atttgaatac ggaaaaatat gatattatac
     2221 caattggaat tacaagggag ggtaattggt atcattatat tggagattat aataatatcc
     2281 agaataacac ttggtttgaa agggatactg atataattcc agttattgtt tcgcagaacc
     2341 gtgtcaaaaa tggtattatt gaatttttaa ttcctgatgc tgtttctcag aatcatattc
     2401 caaatagtgc tattgaatca tgtgaaaatg atattaaata cactaaactt gattttgtgt
     2461 ttcctgtact gcatggaaaa aatggagaag atggaacagt gcaggggtta tttgaattgg
     2521 caggtataca ggttattgga tgtggtactc tttcttcagc attatgtatg gacaaagaca
     2581 aatcacataa acttgttcat tcagaaggta ttaaagtacc aaaatcaata ttactaaaat
     2641 actcagataa atttaatgtg gctgaactgt caaaagactt aacttatcca ttatttataa
     2701 aacctgtgcg tgcaggttca tcatttggta ttagtaaaat ttataaaaaa gaagagttac
     2761 aagtagcagt agacttggct tttgaacatg ataatgaagt aataattgag gaaaatattg
     2821 atggttttga ggtagggtgt gcagttttag gaaacaatga cttacttgtt ggaagagtag
     2881 atgaaataga attgtcaaaa ggattttttg attatacaga aaaatataca ttgaaaagtt
     2941 caaaaattca tatgccagct agaattgatt tggattgtga gaaaagaata caagagacag
     3001 caaaaattat ttatagaact cttggatgtt ctggatttgc tagagtagat atgtttttaa
     3061 ctccatctgg tgaaattatt tttaatgaag tcaatacaat tcctggcttt acttctcata
     3121 gtcgttatcc aaatatgatg aaaggtattg gactgtcttt tgaagaaata ttggacaaga
     3181 taattgaggt gtacataaaa tgatgaataa tattttatta gataaaaata aagaagataa
     3241 aatgacaaat actatcttat tgactaaaga taaagtttat gatgggaatc taattctagt
     3301 aaatgctttt ttaccagtta aaacatctga agatatagat ttaattcctg tagatacaag
     3361 gtttccaagt attcttatga aacgtgaagc tacaaacatt ttacaaaata ttttaaaaag
     3421 tatatgtgga ataaatgaaa tagtacctgt aagtggatat cgtactgcag aggaacaaca
     3481 agatatatat tcaagttctc tgcgtgacaa tggaaaagac tttactaaaa agtttgtagc
     3541 acttccaaat cacagtgaac atcagacagg gcttgctatt gatttagggt taaagaaaga
     3601 agttatagat tttatctgcc ctgaatttcc ttataatggt atttgtaatg agtttcgtaa
     3661 ggcagcacta cattatggtt ttatagagcg ttatcagtgt aaaaaagaag aaataacagg
     3721 aatatctcaa gaaccatggc attttcgtta tgtgggatat ccgcattctg agattatcaa
     3781 taaaatgaat ctcgctcttg aagaatatat agaatatatt aagagatttt cgtatacaaa
     3841 ttgtttaaaa atagaagata aagaaaaaat tatagaaatc ttttatgtgc ctattcatac
     3901 taaagaagaa gtgagaatct ctatacctga acaatgtgta tatcaaatat cgggtaacaa
     3961 taaggatggt tttattgtga cattttggag aaatagaaag gactaagaaa tggaggaaca
     4021 agaatgatta ggaataaatc ttatgcaggg cttgattatt ttaggattat agctgcatta
     4081 cttataattg caattcatac atctccatta ttatcatata gtaaaatggc tgactttgtg
     4141 ttaactagta taattgctcg tattgctgtg ccattctttt ttatgctatc aggctttttt
     4201 ctaatttcaa catataatta taattgtaat aaactgaaat cttttctaaa aaatgtatta
     4261 tttatttacg ggatagctat tgtaatttat attcccttaa atatttacac tggatatttt
     4321 tccatgaata atttagtgcc caatattatt aaggacattg tatttgatgg gactttatat
     4381 catttatggt atcttcctgc atcaattatt ggtgcaagta ttgcatactt tcttgtaaaa
     4441 aaactaggtt taaagtactc actagtaatc actattgtta tttatgtaat tggtatgttt
     4501 ggtgatagtt attatggttt tttagaaaaa ataccactat taaagaattt atatgggtat
     4561 atttttgaag tatcagatta tacacgaaat ggtatatttt ttgcacctgt atttttcata
     4621 cttggtggaa taatatctaa taaatctaat tatatgtcaa ctaaaaatag cttgattgga
     4681 tttcttatat cattcttact tatgttatgt gagggaatgt ttttacataa actaggggta
     4741 cagcgtcatg atagcatgta tattatgtta ttgccatgta tgtatttctt atttacagcc
     4801 ttaacatttt tgaaaggttc tcgagctagg ttattgcgaa catcatcatt aattatttat
     4861 attatacatc ctatgatgat tgttgttatt cgtatgtttt ctaaaatatt cggaatacaa
     4921 actgtcttgg ttgacaatag ccttattcat tatatagtgg taagtatagc atcttttata
     4981 gcttctataa ttattatatt gattcttaaa cctctaaaaa aagacttgaa aggagaacat
     5041 aaggtaaata ccaatagagc ttggattgaa attgatttaa ataatttgga acataatgta
     5101 aagatgatac aaaaagctat gccagaagat tgtgaattga tggcagttgt aaaagctaat
     5161 gcctatggtc atagtgcttt tgaagtagcg acttgtgcaa accaaatagg tgtaaaagca
     5221 tttgcagtag caacaataga tgaggggatt gatttacgtc gatatggaat actaggagaa
     5281 atattgattc ttggatatac taacccaata agggcaaagg aacttcataa atacaatctt
     5341 acacagagtg ttattgacct taatcatgct atctctttaa acaaacagaa atacaacata
     5401 aaatcacaca ttaaaattga tacaggtatg cacagactgg gttttgatgt taatgatgtg
     5461 aggtcaattt taaaggcatt taaattaaaa tacttagata tatgtggcat atttacacac
     5521 ttgtgtgttt cagatagtct gaaagatgaa gatgtagact ttacaaataa acaaattgaa
     5581 tgtttttata agttaattga ttttctgtta aaaaaaggta taaaaattcc taaagtacat
     5641 attcaaagta gttatggttt ttttaattat cccaatctta agtgtaatta tgtaagaatt
     5701 ggaattgcat tatacgggat attaagtttt ccaaatgata cgactaaatt gcaacttgat
     5761 ttacgacctg ttttatcctt aaaatcacaa gtaattctta ttagaaaaat acaaaaagat
     5821 gatagttttg gatatggaag agtctttatt gcaagcagag atagcgtaat tgctatatta
     5881 tctattggct atgccgatgg tatacctaga aatttatcct gtggaaaaag ttacgtaata
     5941 ataaatggtt gtagagcagc aatagtgggt cgaatttgca tggaccaact tgctgttgat
     6001 attacagata tacctaatgt agaagttggt aatacggcaa taataatagg aagagataat
     6061 ttatctgaat tatctgtttc tgaagttgca aataactcat gtagtatatc gaatgaatta
     6121 ttgagcagag taggaagaag gttaaatgtt ataaagaagt aactcaatta aatagtaata
     6181 tttgttgtac tgtgtaattt attttactct gactagacat ttttagtaat attatgtcta
     6241 atatatattt tttataactt acatgacaat ttaagttata aaaaggtg
//
LOCUS       DAJMZY010000277         1425 bp    DNA     linear   BCT 07-OCT-2022
DEFINITION  TPA_asm: Clostridioides difficile isolate
            dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3
            SAMN31175469-rid15559633.guided.228, whole genome shotgun sequence.
ACCESSION   DAJMZY010000277 DAJMZY010000000
VERSION     DAJMZY010000277.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN31175469
            Sequence Read Archive: SRR21823174
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1425)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1425)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-OCT-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001444953.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001444953.1
            Genome Coverage       :: 72x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/07/2022 08:32:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,903
            CDSs (total)                      :: 3,817
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 86
            rRNAs                             :: 8, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 20 of 52
            Pseudo Genes (incomplete)         :: 27 of 52
            Pseudo Genes (internal stop)      :: 14 of 52
            Pseudo Genes (multiple problems)  :: 7 of 52
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1425
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN31175469-rid15559633.guided.228"
                     /isolate="dcd42a57-d39b-44fd-b8a8-6fb5051aa1c3"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2015-10-30"
                     /collected_by="UNIVERSITE LAVAL"
     gene            259..975
                     /locus_tag="OE968_003902"
     CDS             259..975
                     /locus_tag="OE968_003902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCP7221082.1"
                     /translation="MNSYNILVVEDEKEIADAIEIYLLNQGYNVFKGYNGLEGLKVIE
                     NQEIHLAIVDIMMPKMDGITLTMKLRENYNFPVIMLSAKSEEVDKIMGLNIGADDYVT
                     KPFKPLELLARVNSQLRRYTKYLNMVGNKEQKVESDDSVFAIGGLELNENTKEVSIDG
                     KYIKTTPIEFKILSLLMRNAGRVFSADEIYERVWNENAVNTDTVMVHVRNIREKIEID
                     PKNPKYLKVVWGVGYKIEKI"
     gene            950..>1425
                     /locus_tag="OE968_003903"
     CDS             950..>1425
                     /locus_tag="OE968_003903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HCP7221083.1"
                     /translation="MDTKLKKFKDKYIVTIIVFILMLSASLGMISQYSTIQASAKGGA
                     ENPFEQESFVDSIYKGSYVLYHNMKEEQEGKMIQPSKLFINEETMNYIKNVSKEKDTY
                     DGSETYYTDDSINADFNENFENWEHFIKASGKNLKYYLVDKESNFEFFNDNKELGVL"
BASE COUNT          618 a          120 c          251 g          436 t
ORIGIN      
        1 attttaaata tatttaaatc tttagaaaat ctttagaaaa gtatatgtaa tatcttaagt
       61 ttttaatttt aatattaagt atataaaaca aaatgaaaaa atattaaatt taaactagaa
      121 ggaggtttct aagatggaca ttaaatacaa ataaccagaa caaaagatat aaatatatat
      181 ataaatggaa aaacttctat catattgtat aatcatatat gtaaagaaaa tttataaatt
      241 aatataaagg agattagaat gaattcatat aatattttgg tggtagaaga tgaaaaggag
      301 atagcagatg ctatagaaat atatctatta aatcaaggat ataatgtttt taagggatac
      361 aatggattag aaggtcttaa ggttatagaa aaccaagaaa tacatttagc tatagttgat
      421 ataatgatgc ctaaaatgga tggtataaca cttacaatga agcttagaga aaactataat
      481 tttccagtaa taatgctatc tgcaaaatca gaagaagttg acaaaataat ggggcttaat
      541 ataggagcag acgattatgt aacaaaacct tttaagccat tagaactatt ggctagagtt
      601 aattcacaac ttagaaggta cactaagtat ctaaacatgg ttggaaataa agagcaaaag
      661 gtagaaagtg acgatagtgt gtttgcaata ggcggattag aattaaatga aaatacaaaa
      721 gaagttagta ttgatggaaa gtatataaaa acaactccta tagaatttaa aatactaagt
      781 ttacttatga gaaatgcagg aagagttttt tctgctgatg aaatatatga aagagtttgg
      841 aatgagaatg ctgtaaatac agatacagtt atggtacatg tgaggaatat aagggaaaag
      901 atagaaattg acccaaaaaa tcctaaatat ttaaaggtgg tgtggggtgt tggatacaaa
      961 attgaaaaaa tttaaagata aatatatagt tactattata gtttttatac ttatgttatc
     1021 agcatcatta ggtatgatta gtcaatattc tactatacaa gcaagtgcta aaggtggagc
     1081 agagaatcca tttgaacagg aaagctttgt agatagtata tataaaggaa gttatgtttt
     1141 atatcataat atgaaggaag aacaagaagg taagatgata caaccatcaa agctatttat
     1201 caatgaagaa actatgaact atataaaaaa tgtaagtaaa gaaaaagata cttatgatgg
     1261 ttcagaaact tattatacag atgatagtat taatgcagat tttaatgaaa actttgaaaa
     1321 ttgggagcat ttcattaaag cgtcaggaaa gaatttaaag tactatttag ttgataaaga
     1381 aagcaatttt gaatttttta atgataataa agaattagga gtact
//
